In [1]:
# Parameters
data_name = "Tcf12"
task_idxs = "0-213,216-278"
homer_root = "/srv/scratch/msharmin/mouse_hem/with_tfd/full_mouse50/Naive_scans"
modisco_root = "/srv/scratch/msharmin/mouse_hem/with_tfd/full_mouse50/Naive_modisco2019"
overwrite = False
In [2]:
from matlas.reports import collect_motifDB_to_be_displayed, display_comparative_cell_types

load data from labcluster

Using TensorFlow backend.
2019-08-23 11:42:12,689 [WARNING] git-lfs not installed
In [3]:
homer_matches, modisco_matches = collect_motifDB_to_be_displayed(task_idxs, homer_root, modisco_root, 
                                                              overwrite=False)

TF-MoDISco is using the TensorFlow backend.
In [4]:
display_comparative_cell_types(data_name, homer_matches, modisco_matches)
Tcf12: Motif: M08762_2.00



Forward PWM

Reverse PWM

Shared Cell types both TF-MoDISco and Homer finds Tcf12: #32

Cell typeModiscoHomer
wES;limb;E14.5;D;En

Pattern: metacluster_1/pattern_1

Significance: 0.05664119999999999

Pattern: motif5.motif

Significance: 0.024444999999999998

wES;limb;E11.5;D;En

Pattern: metacluster_0/pattern_6

Significance: 0.0366082

Pattern: motif12.motif

Significance: 0.026376099999999996

wES;Fr_lmb;E11.5;D;En

Pattern: metacluster_1/pattern_3

Significance: 0.0164632

Pattern: motif6.motif

Significance: 0.0222502

wES;FaceP;E14.5;D;En

Pattern: metacluster_0/pattern_1

Significance: 0.0568121

Pattern: motif5.motif

Significance: 0.051902300000000005

proB;A;CL

Pattern: metacluster_1/pattern_3

Significance: 0.021928200000000002

Pattern: motif15.motif

Significance: 0.0457243

preB;A;CL

Pattern: metacluster_1/pattern_4

Significance: 0.0140918

Pattern: motif12.motif

Significance: 0.04511130000000001

wES;FaceP;E11.5;D;En

Pattern: metacluster_1/pattern_2

Significance: 0.0522668

Pattern: motif7.motif

Significance: 0.0175865

wES;NRL_Tube;E11.5;D;En

Pattern: metacluster_1/pattern_5

Significance: 0.00507416

Pattern: motif15.motif

Significance: 0.0546436

SKLTL_Muscle;8wks;D;En

Pattern: metacluster_1/pattern_12

Significance: 0.0255789

Pattern: motif10.motif

Significance: 0.0498593

prePLSM_B;A;GEO

Pattern: metacluster_1/pattern_20

Significance: 0.032773199999999995

Pattern: motif22.motif

Significance: 0.023848599999999998

plasmaB;A;CL

Pattern: metacluster_1/pattern_5

Significance: 0.00663135

Pattern: motif9.motif

Significance: 0.022834200000000002

preB_BMD;A;GEO

Pattern: metacluster_1/pattern_5

Significance: 0.010160700000000002

Pattern: motif9.motif

Significance: 0.017527

B;B220_CD43;A;GEO

Pattern: metacluster_1/pattern_9

Significance: 0.015346200000000003

Pattern: motif11.motif

Significance: 0.014593700000000001

largeDPprecrsr;CD4+CD8+CD69-;A;CL

Pattern: metacluster_1/pattern_5

Significance: 0.0106137

Pattern: motif18.motif

Significance: 0.0420829

smallDPprecrsor;CD4+CD8+CD69-;A;CL

Pattern: metacluster_1/pattern_4

Significance: 0.013636500000000001

Pattern: motif13.motif

Significance: 0.017336700000000003

NPC;F129;A;GEO

Pattern: metacluster_1/pattern_5

Significance: 0.046899699999999996

Pattern: motif10.motif

Significance: 0.058119000000000004

NPC;G4;A;GEO

Pattern: metacluster_1/pattern_5

Significance: 0.014310900000000001

Pattern: motif9.motif

Significance: 0.024250599999999997

NPC;Ch13;A;GEO

Pattern: metacluster_1/pattern_9

Significance: 0.0430599

/

Pattern: metacluster_1/pattern_17

Significance: 0.0260098

Pattern: motif13.motif

Significance: 0.0224112

NPC;mE6;A;GEO

Pattern: metacluster_1/pattern_7

Significance: 0.0342872

Pattern: motif11.motif

Significance: 0.0251742

DP;A;CL

Pattern: metacluster_1/pattern_10

Significance: 0.013592600000000002

Pattern: motif17.motif

Significance: 0.033786699999999996

iPV_NRN;A;GEO

Pattern: metacluster_1/pattern_3

Significance: 0.000106758

Pattern: motif3.motif

Significance: 0.0128835

DP3b;A;CL

Pattern: metacluster_1/pattern_3

Significance: 0.0172262

Pattern: motif7.motif

Significance: 0.0585529

ISP;A;CL

Pattern: metacluster_1/pattern_4

Significance: 0.013942700000000002

Pattern: motif14.motif

Significance: 0.020434599999999997

Muscle;A;CL

Pattern: metacluster_1/pattern_16

Significance: 0.00190421

Pattern: motif19.motif

Significance: 0.013110499999999999

Heart;D;En

Pattern: metacluster_0/pattern_8

Significance: 0.0376882

Pattern: motif13.motif

Significance: 0.056486800000000004

KDNY;P0;D;En

Pattern: metacluster_1/pattern_9

Significance: 0.042651999999999995

Pattern: motif15.motif

Significance: 0.0503232

LNG;P0;D;En

Pattern: metacluster_1/pattern_11

Significance: 0.0412994

Pattern: motif18.motif

Significance: 0.016452500000000002

CRBL_GRNL_Precrsr;A;GEO

Pattern: metacluster_0/pattern_0

Significance: 0.05196619999999999

Pattern: motif2.motif

Significance: 0.054386699999999996

RTN;D1;D;En

Pattern: metacluster_0/pattern_4

Significance: 0.0280297

Pattern: motif16.motif

Significance: 0.041657599999999996

wES;MSDRM;E11.5;D;En

Pattern: metacluster_0/pattern_1

Significance: 0.0214325

Pattern: motif4.motif

Significance: 0.0319843

wES.Fr_BRN;E14.4;D;En

Pattern: metacluster_0/pattern_4

Significance: 0.036475

Pattern: motif11.motif

Significance: 0.035080599999999997

wES;Md_BRN;E11.5;D;En

Pattern: metacluster_0/pattern_4

Significance: 0.030710900000000003

Pattern: motif19.motif

Significance: 0.05435449999999999

Unique Cell types only TF-MoDISco finds Tcf12: #38

Cell typeModiscoHomer
GCN_PHT_RCPTR;A;GEO

Pattern: metacluster_1/pattern_13

Significance: 0.0307514

Absent
CN_PHT_RCPTR;A;GEO

Pattern: metacluster_1/pattern_13

Significance: 0.0518774

Absent
wES;3rd_Rhmbmr;E8.5;A;GEO

Pattern: metacluster_0/pattern_10

Significance: 0.0273226

Absent
npES;3rd_Rhmbmr_delC;E8.5;A;GEO

Pattern: metacluster_0/pattern_24

Significance: 0.040982599999999994

Absent
npES;5th_Rhmbmr_delC;E8.5;A;GEO

Pattern: metacluster_1/pattern_21

Significance: 0.00270262

Absent
wES;5th_Rhmbmr;E9.5;A;GEO

Pattern: metacluster_0/pattern_15

Significance: 0.011713600000000001

/

Pattern: metacluster_0/pattern_24

Significance: 0.0356286

Absent
wES;5th_Rhmbmr;E8.5;A;GEO

Pattern: metacluster_0/pattern_12

Significance: 0.0355944

/

Pattern: metacluster_0/pattern_22

Significance: 0.0325345

Absent
npES;5th_Rhmbmr_delA;E8.5;A;GEO

Pattern: metacluster_0/pattern_5

Significance: 0.0452741

Absent
wES;posterior;1;E9.5;A;GEO

Pattern: metacluster_1/pattern_5

Significance: 0.0308452

Absent
wES;posterior;2;E9.5;A;GEO

Pattern: metacluster_0/pattern_9

Significance: 0.00963377

/

Pattern: metacluster_0/pattern_25

Significance: 0.0433015

Absent
wES;posterior;1;E8.5;A;GEO

Pattern: metacluster_0/pattern_10

Significance: 0.0259443

Absent
npES;posterior_delA;E8.5;A;GEO

Pattern: metacluster_0/pattern_8

Significance: 0.016771099999999997

Absent
npES;posterior_delC;E8.5;A;GEO

Pattern: metacluster_0/pattern_9

Significance: 0.023395

Absent
wES.CRNL_NRL_CRST;E10.5;A;GEO

Pattern: metacluster_0/pattern_5

Significance: 0.05230599999999999

Absent
iVIP_NRN;A;GEO

Pattern: metacluster_1/pattern_0

Significance: 0.055333600000000004

/

Pattern: metacluster_1/pattern_23

Significance: 0.035108099999999996

Absent
G_NRN_P;A;GEO

Pattern: metacluster_1/pattern_0

Significance: 0.00845114

Absent
Corticotrope;A;GEO

Pattern: metacluster_0/pattern_17

Significance: 0.0432914

Absent
LNG;A;CL

Pattern: metacluster_1/pattern_20

Significance: 0.031094

Absent
Melanotrope;A;GEO

Pattern: metacluster_0/pattern_8

Significance: 0.018688299999999998

Absent
npES;ZHBTC4;Brg1fl_fl;untreat;A;GEO

Pattern: metacluster_1/pattern_7

Significance: 0.0581386

Absent
BRN;OLFTRY_BLB;A;CL

Pattern: metacluster_0/pattern_13

Significance: 0.0134452

Absent
BRN;FRNTL_CRTX;A;CL

Pattern: metacluster_1/pattern_12

Significance: 0.031653

Absent
BRN;SNSR_MTR_CRTX;A;CL

Pattern: metacluster_1/pattern_6

Significance: 0.0586231

Absent
ES;ZhBTc4;2;D;GEO

Pattern: metacluster_1/pattern_9

Significance: 0.045941699999999995

Absent
WHL_BRN;8wks;D;GEO

Pattern: metacluster_1/pattern_2

Significance: 0.0588839

/

Pattern: metacluster_1/pattern_10

Significance: 0.0258066

Absent
wES;WHL_BRN;E14.5;D;GEO

Pattern: metacluster_0/pattern_2

Significance: 0.00808333

Absent
wCH12_drug;A;CL

Pattern: metacluster_1/pattern_17

Significance: 0.0378463

Absent
LNG;8wks;D;En

Pattern: metacluster_0/pattern_17

Significance: 0.0286185

Absent
Heart;8wks;D;En

Pattern: metacluster_0/pattern_11

Significance: 0.0324286

Absent
wES;RTN;E11.5;D;En

Pattern: metacluster_0/pattern_3

Significance: 0.0354625

Absent
Fr_BRN;P0;D;En

Pattern: metacluster_1/pattern_4

Significance: 0.055504899999999996

/

Pattern: metacluster_1/pattern_15

Significance: 0.0280822

Absent
Hnd_BRN;P0;D;En

Pattern: metacluster_1/pattern_3

Significance: 0.054037

Absent
wES;Hnd_BRN;E11.5;D;En

Pattern: metacluster_0/pattern_4

Significance: 0.013313499999999999

Absent
wES;Hnd_BRN;E14.5;D;En

Pattern: metacluster_0/pattern_7

Significance: 0.055456200000000004

/

Pattern: metacluster_0/pattern_12

Significance: 0.0463375

Absent
wES;Md_BRN;E14.4;D;En

Pattern: metacluster_0/pattern_4

Significance: 0.0335872

Absent
Md_BRN;D;En

Pattern: metacluster_1/pattern_5

Significance: 0.0217792

Absent
wES;WHL_BRN;E14.5;D;En

Pattern: metacluster_1/pattern_5

Significance: 0.041712099999999995

/

Pattern: metacluster_1/pattern_6

Significance: 0.057750800000000005

Absent
WHL_BRN;8wks;D;En

Pattern: metacluster_1/pattern_11

Significance: 0.0506764

Absent
Unique Cell types only Homer finds Tcf12: #5

Cell typeModiscoHomer
wES;Hnd_lmb;E11.5;D;EnAbsent

Pattern: motif11.motif

Significance: 0.048824900000000004

wES;LNG;E14.5;D;EnAbsent

Pattern: motif13.motif

Significance: 0.0143565

A20;B-lymphoma;D;EnAbsent

Pattern: motif13.motif

Significance: 0.026335

DP3a;A;CLAbsent

Pattern: motif12.motif

Significance: 0.0322484

3T3-L1;D;EnAbsent

Pattern: motif15.motif

Significance: 0.0411286