In [1]:
# Parameters
data_name = "Gata3"
task_idxs = "0-213,216-278"
homer_root = "/srv/scratch/msharmin/mouse_hem/with_tfd/full_mouse50/Naive_scans"
modisco_root = "/srv/scratch/msharmin/mouse_hem/with_tfd/full_mouse50/Naive_modisco2019"
overwrite = False
In [2]:
from matlas.reports import collect_motifDB_to_be_displayed, display_comparative_cell_types

load data from labcluster

Using TensorFlow backend.
2019-08-23 11:09:50,111 [WARNING] git-lfs not installed
In [3]:
homer_matches, modisco_matches = collect_motifDB_to_be_displayed(task_idxs, homer_root, modisco_root, 
                                                              overwrite=False)

TF-MoDISco is using the TensorFlow backend.
In [4]:
display_comparative_cell_types(data_name, homer_matches, modisco_matches)
Gata3: Motif: M09552_2.00



Forward PWM

Reverse PWM

Shared Cell types both TF-MoDISco and Homer finds Gata3: #23

Cell typeModiscoHomer
STMCH;P0;D;En

Pattern: metacluster_1/pattern_17

Significance: 0.0351324

Pattern: motif13.motif

Significance: 0.018770099999999998

416B;HMTP_SPNSN;CD34+;D;En

Pattern: metacluster_1/pattern_11

Significance: 0.0090759

Pattern: motif11.motif

Significance: 0.05652669999999999

Erythroid;Ter119+;A;GEO

Pattern: metacluster_0/pattern_7

Significance: 0.0100316

Pattern: motif8.motif

Significance: 0.047604

AML;AE9a;A;GEO

Pattern: metacluster_1/pattern_3

Significance: 0.00963149

Pattern: motif3.motif

Significance: 0.00412102

Mast;A;CL

Pattern: metacluster_0/pattern_7

Significance: 0.0379499

Pattern: motif6.motif

Significance: 0.0424321

BSPHL;A;CL

Pattern: metacluster_1/pattern_8

Significance: 0.04175209999999999

Pattern: motif7.motif

Significance: 0.048181800000000004

MEF.GATA-1-ER;D;En

Pattern: metacluster_1/pattern_9

Significance: 0.029416900000000003

Pattern: motif4.motif

Significance: 0.0122237

MEL;D;En

Pattern: metacluster_1/pattern_7

Significance: 0.037860000000000005

Pattern: motif4.motif

Significance: 0.00687266

SKN_EPTHL;A;GEO

Pattern: metacluster_0/pattern_6

Significance: 0.039887599999999995

Pattern: motif14.motif

Significance: 0.00564225

LRG_INTSTN;A;CL

Pattern: metacluster_0/pattern_12

Significance: 0.0354103

Pattern: motif6.motif

Significance: 0.053671500000000004

MegEP;A;CL

Pattern: metacluster_1/pattern_2

Significance: 0.0439756

Pattern: motif2.motif

Significance: 0.042435

pErythroblast;A;En

Pattern: metacluster_1/pattern_9

Significance: 0.047190499999999996

Pattern: motif11.motif

Significance: 0.00329359

MegP;A;En

Pattern: metacluster_1/pattern_6

Significance: 0.019768

Pattern: motif7.motif

Significance: 0.0156363

pCMP;A;CL

Pattern: metacluster_1/pattern_5

Significance: 0.00776433

Pattern: motif7.motif

Significance: 0.0451515

LNG_TRM_HSC;A;CL

Pattern: metacluster_1/pattern_10

Significance: 0.012228600000000001

Pattern: motif14.motif

Significance: 0.051117199999999995

ILC2precrsr;A;CL

Pattern: metacluster_1/pattern_6

Significance: 0.0561466

Pattern: motif18.motif

Significance: 0.028250400000000002

/

Pattern: motif25.motif

Significance: 0.00697623

416B_MP;CD34+;D;GEO

Pattern: metacluster_1/pattern_12

Significance: 0.0112804

Pattern: motif12.motif

Significance: 0.052749000000000004

ILC2;A;CL

Pattern: metacluster_1/pattern_5

Significance: 0.039488300000000004

Pattern: motif19.motif

Significance: 0.000109616

wES;LVR;E11.5;D.;En

Pattern: metacluster_1/pattern_5

Significance: 0.0541107

Pattern: motif3.motif

Significance: 0.057259500000000005

LVR;P0;D;En

Pattern: metacluster_1/pattern_7

Significance: 0.05555319999999999

Pattern: motif13.motif

Significance: 0.0228304

Heart;P0;D;En

Pattern: metacluster_1/pattern_13

Significance: 0.0135944

Pattern: motif13.motif

Significance: 0.028301999999999997

EP;c-kit+CD71+Ter119+;D;En

Pattern: metacluster_1/pattern_8

Significance: 0.00770678

Pattern: motif5.motif

Significance: 0.0528317

416B_MP;CD34+;D;En

Pattern: metacluster_1/pattern_13

Significance: 0.0076208

Pattern: motif9.motif

Significance: 0.017726

Unique Cell types only TF-MoDISco finds Gata3: #39

Cell typeModiscoHomer
proB;A;CL

Pattern: metacluster_1/pattern_11

Significance: 0.0327449

Absent
iNKT;A;GEO

Pattern: metacluster_1/pattern_19

Significance: 0.024988099999999996

/

Pattern: metacluster_1/pattern_22

Significance: 0.0406429

Absent
B;B220_CD43;A;GEO

Pattern: metacluster_1/pattern_24

Significance: 0.0343038

Absent
ESNPHL_ex-vivo_BlbC;A;CL

Pattern: metacluster_0/pattern_18

Significance: 0.035041199999999995

Absent
ESNPHL_SPLND_BlbCA;CL

Pattern: metacluster_0/pattern_15

Significance: 0.015272899999999999

Absent
ENDRM_ESD;A;GEO

Pattern: metacluster_1/pattern_13

Significance: 0.034452699999999996

Absent
MTR_NRN_MN1;methyl3;D;En

Pattern: metacluster_0/pattern_14

Significance: 0.0549867

Absent
MN1;D;En

Pattern: metacluster_1/pattern_20

Significance: 0.011371700000000002

Absent
aNonTfh;A;CL

Pattern: metacluster_1/pattern_20

Significance: 0.031261000000000004

Absent
Tfr_mut;CD4+CD44+CXCR5+PD1+CD25+;A;CL

Pattern: metacluster_1/pattern_20

Significance: 0.0200353

Absent
wES;5th_Rhmbmr;E8.5;A;GEO

Pattern: metacluster_0/pattern_26

Significance: 0.024202900000000003

Absent
CD4+CD8intTCR+CD69+CD24+;B2defM;A;CL

Pattern: metacluster_1/pattern_16

Significance: 0.0207879

Absent
npES;posterior_delA;E8.5;A;GEO

Pattern: metacluster_0/pattern_18

Significance: 0.0350017

Absent
BCK_SKN;A;GEO

Pattern: metacluster_0/pattern_19

Significance: 0.00705486

Absent
CD4+CD8-TCR+CD25-Foxp3+;A;CL

Pattern: metacluster_1/pattern_17

Significance: 0.0213202

Absent
Erythroblast;A;CL

Pattern: metacluster_1/pattern_9

Significance: 0.05420030000000001

Absent
DP3a;A;CL

Pattern: metacluster_1/pattern_15

Significance: 0.010493

Absent
SML_INTSTN;A;CL

Pattern: metacluster_0/pattern_16

Significance: 0.0549068

Absent
Heart;D;En

Pattern: metacluster_0/pattern_17

Significance: 0.037737400000000004

Absent
placenta;A;CL

Pattern: metacluster_0/pattern_17

Significance: 0.0317356

Absent
EPP;A;En

Pattern: metacluster_1/pattern_9

Significance: 0.0416448

Absent
STMCH;A;CL

Pattern: metacluster_1/pattern_23

Significance: 0.0341394

Absent
LVR;8wks;D;GEO

Pattern: metacluster_1/pattern_19

Significance: 0.028785500000000002

Absent
LNG;8wks;D;GEO

Pattern: metacluster_0/pattern_22

Significance: 0.038000400000000004

Absent
SHRT_TRM_HSC;A;CL

Pattern: metacluster_1/pattern_14

Significance: 0.013833700000000003

Absent
T_SPLND_blstCLTRD;CD4+;D;GEO

Pattern: metacluster_1/pattern_13

Significance: 0.053014

Absent
apCD4Eff;D;GEO

Pattern: metacluster_1/pattern_16

Significance: 0.04399190000000001

Absent
NCR+ILC3;A;CL

Pattern: metacluster_1/pattern_18

Significance: 0.0136797

Absent
ILC2_Nippo;A;CL

Pattern: metacluster_1/pattern_10

Significance: 0.0446921

Absent
NCR+ILC3+IL23;A;CL

Pattern: metacluster_1/pattern_16

Significance: 0.045524199999999994

Absent
Th2_nippo;A;CL

Pattern: metacluster_1/pattern_10

Significance: 0.0450086

Absent
LNG;8wks;D;En

Pattern: metacluster_0/pattern_22

Significance: 0.038990199999999996

Absent
Heart;8wks;D;En

Pattern: metacluster_0/pattern_18

Significance: 0.0526533

Absent
Adipose;D;En

Pattern: metacluster_0/pattern_24

Significance: 0.05776749999999999

Absent
ILC2+IL33+IL25;A;GEO

Pattern: metacluster_1/pattern_9

Significance: 0.05540790000000001

Absent
ILC2;A;GEO

Pattern: metacluster_1/pattern_10

Significance: 0.00418936

Absent
ILC3;A;GEO

Pattern: metacluster_1/pattern_19

Significance: 0.012286700000000001

Absent
abTreg;CD4+_CD25+;8wks;D;En

Pattern: metacluster_1/pattern_16

Significance: 0.0214655

Absent
ILC2_AbxGRMFree;A;GEO

Pattern: metacluster_1/pattern_14

Significance: 0.044791000000000004

Absent
Unique Cell types only Homer finds Gata3: #1

Cell typeModiscoHomer
MEL_Znc_di-cl;24h;D;EnAbsent

Pattern: motif6.motif

Significance: 0.043162900000000004