In [1]:
# Parameters
data_name = "Sox4"
task_idxs = "0-213,216-278"
homer_root = "/srv/scratch/msharmin/mouse_hem/with_tfd/full_mouse50/Naive_scans"
modisco_root = "/srv/scratch/msharmin/mouse_hem/with_tfd/full_mouse50/Naive_modisco2019"
overwrite = False
In [2]:
from matlas.reports import collect_motifDB_to_be_displayed, display_comparative_cell_types
load data from labcluster
Using TensorFlow backend.
2019-08-23 11:36:20,552 [WARNING] git-lfs not installed
In [3]:
homer_matches, modisco_matches = collect_motifDB_to_be_displayed(task_idxs, homer_root, modisco_root, 
                                                              overwrite=False)
TF-MoDISco is using the TensorFlow backend.
In [4]:
display_comparative_cell_types(data_name, homer_matches, modisco_matches)
Sox4: Motif: M09410_2.00



Forward PWM

Reverse PWM

Shared Cell types both TF-MoDISco and Homer finds Sox4: #21

Cell typeModiscoHomer
ENDRM_ESD;A;GEO

Pattern: metacluster_1/pattern_5

Significance: 0.00674688

Pattern: motif9.motif

Significance: 0.029236500000000002

npES;3rd_Rhmbmr_delA;E8.5;A;GEO

Pattern: metacluster_0/pattern_2

Significance: 0.006281

Pattern: motif3.motif

Significance: 0.00187683

wES;3rd_Rhmbmr;E8.5;A;GEO

Pattern: metacluster_0/pattern_1

Significance: 0.00888291

Pattern: motif2.motif

Significance: 0.0201657

npES;3rd_Rhmbmr_delC;E8.5;A;GEO

Pattern: metacluster_0/pattern_1

Significance: 0.00728594

Pattern: motif3.motif

Significance: 0.00051925

npES;5th_Rhmbmr_delC;E8.5;A;GEO

Pattern: metacluster_1/pattern_2

Significance: 0.0091527

Pattern: motif8.motif

Significance: 0.00670202

wES;5th_Rhmbmr;E9.5;A;GEO

Pattern: metacluster_0/pattern_3

Significance: 0.00452083

/

Pattern: metacluster_0/pattern_10

Significance: 0.045826

Pattern: motif3.motif

Significance: 0.00293655

wES;5th_Rhmbmr;E8.5;A;GEO

Pattern: metacluster_0/pattern_3

Significance: 0.0100903

Pattern: motif3.motif

Significance: 0.0289586

npES;5th_Rhmbmr_delA;E8.5;A;GEO

Pattern: metacluster_0/pattern_3

Significance: 0.00732673

/

Pattern: metacluster_0/pattern_17

Significance: 0.056746300000000006

Pattern: motif4.motif

Significance: 0.00114587

wES;posterior;1;E9.5;A;GEO

Pattern: metacluster_1/pattern_4

Significance: 0.00560447

Pattern: motif6.motif

Significance: 0.0253197

wES;posterior;2;E9.5;A;GEO

Pattern: metacluster_0/pattern_3

Significance: 0.00938326

Pattern: motif3.motif

Significance: 0.00062266

wES;posterior;1;E8.5;A;GEO

Pattern: metacluster_0/pattern_3

Significance: 0.0138143

Pattern: motif8.motif

Significance: 0.051841

npES;posterior_delC;E8.5;A;GEO

Pattern: metacluster_0/pattern_3

Significance: 0.0102737

Pattern: motif4.motif

Significance: 0.00369568

NPC;F129;A;GEO

Pattern: metacluster_1/pattern_4

Significance: 0.00747998

Pattern: motif14.motif

Significance: 0.027494099999999997

NPC;Ch13;A;GEO

Pattern: metacluster_1/pattern_4

Significance: 0.00318825

Pattern: motif4.motif

Significance: 0.0139929

NPC;mE6;A;GEO

Pattern: metacluster_1/pattern_3

Significance: 0.00552389

Pattern: motif7.motif

Significance: 0.0189149

ES;E14;A;CL

Pattern: metacluster_1/pattern_3

Significance: 0.0080676

Pattern: motif7.motif

Significance: 0.00206934

ES;ZhBTc4;1;D;GEO

Pattern: metacluster_1/pattern_7

Significance: 0.0107973

Pattern: motif20.motif

Significance: 0.0037567

ES;ZhBTc4;2;D;GEO

Pattern: metacluster_1/pattern_5

Significance: 0.00547122

Pattern: motif7.motif

Significance: 0.00990351

wES;RTN;E11.5;D;En

Pattern: metacluster_0/pattern_5

Significance: 0.00784392

Pattern: motif13.motif

Significance: 0.00501142

wES;Hnd_BRN;E11.5;D;En

Pattern: metacluster_0/pattern_2

Significance: 0.00859767

Pattern: motif7.motif

Significance: 0.00211327

wES;Md_BRN;E11.5;D;En

Pattern: metacluster_0/pattern_3

Significance: 0.0123243

Pattern: motif6.motif

Significance: 0.0286289

Unique Cell types only TF-MoDISco finds Sox4: #53

Cell typeModiscoHomer
wES;limb;E14.5;D;En

Pattern: metacluster_1/pattern_18

Significance: 0.00282207

Absent
wES;limb;E11.5;D;En

Pattern: metacluster_0/pattern_12

Significance: 0.0227202

/

Pattern: metacluster_0/pattern_16

Significance: 0.041598699999999995

Absent
wES;Fr_lmb;E11.5;D;En

Pattern: metacluster_1/pattern_15

Significance: 0.0510168

Absent
wES;Hnd_lmb;E11.5;D;En

Pattern: metacluster_0/pattern_11

Significance: 0.0253696

/

Pattern: metacluster_0/pattern_15

Significance: 0.059132699999999996

/

Pattern: metacluster_0/pattern_22

Significance: 0.031083600000000003

Absent
wES;FaceP;E14.5;D;En

Pattern: metacluster_0/pattern_18

Significance: 0.0217241

Absent
wES;FaceP;E11.5;D;En

Pattern: metacluster_1/pattern_6

Significance: 0.024011599999999998

Absent
wES;NRL_Tube;E11.5;D;En

Pattern: metacluster_1/pattern_2

Significance: 0.0111242

Absent
smallDPprecrsor;CD4+CD8+CD69-;A;CL

Pattern: metacluster_1/pattern_15

Significance: 0.0487423

Absent
CD4+CD8intTCR+CD69+CD24+;B2defM;A;CL

Pattern: metacluster_1/pattern_14

Significance: 0.0549653

Absent
npES;posterior_delA;E8.5;A;GEO

Pattern: metacluster_0/pattern_3

Significance: 0.0286314

/

Pattern: metacluster_0/pattern_13

Significance: 0.0496935

Absent
BCK_SKN;A;GEO

Pattern: metacluster_0/pattern_22

Significance: 0.0500223

/

Pattern: metacluster_0/pattern_23

Significance: 0.00394355

Absent
wES.CRNL_NRL_CRST;E10.5;A;GEO

Pattern: metacluster_0/pattern_15

Significance: 0.00531263

/

Pattern: metacluster_0/pattern_18

Significance: 0.024550799999999998

Absent
NPC;G4;A;GEO

Pattern: metacluster_1/pattern_4

Significance: 0.0159309

Absent
iVIP_NRN;A;GEO

Pattern: metacluster_1/pattern_18

Significance: 0.00316299

/

Pattern: metacluster_1/pattern_22

Significance: 0.04721090000000001

Absent
G_NRN_P;A;GEO

Pattern: metacluster_1/pattern_17

Significance: 0.00329485

Absent
ES;ZhBTc4;untreated;A;GEO

Pattern: metacluster_1/pattern_4

Significance: 0.0178269

Absent
npES;ZHBTC4;doxyc;treat;A;GEO

Pattern: metacluster_0/pattern_5

Significance: 0.0223138

Absent
npES;ZHBTC4;Brg1fl_fl;untreat;A;GEO

Pattern: metacluster_1/pattern_11

Significance: 0.0165061

Absent
ES;JM8.N4;Asynch;A;GEO

Pattern: metacluster_0/pattern_10

Significance: 0.00742897

Absent
Mammary;A;CL

Pattern: metacluster_0/pattern_10

Significance: 0.00574347

Absent
ES;JM8.N4;Mitosis;A;GEO

Pattern: metacluster_0/pattern_7

Significance: 0.011164

Absent
Mammary_BptfKO;A;GEO

Pattern: metacluster_0/pattern_9

Significance: 0.00452942

Absent
SPNL_CHRD;A;CL

Pattern: metacluster_1/pattern_6

Significance: 0.0183864

Absent
NRV;Eye-OPTC;A;CL

Pattern: metacluster_0/pattern_2

Significance: 0.019172099999999997

Absent
BRN;OLFTRY_BLB;A;CL

Pattern: metacluster_0/pattern_17

Significance: 0.0128291

Absent
BRN;PTMN;A;CL

Pattern: metacluster_1/pattern_16

Significance: 0.032793699999999995

Absent
BRN;MDL_OBLNGT;A;CL

Pattern: metacluster_1/pattern_4

Significance: 0.052629300000000004

Absent
BRN;SNSR_MTR_CRTX;A;CL

Pattern: metacluster_1/pattern_17

Significance: 0.0168666

Absent
ES;D0;D;GEO

Pattern: metacluster_0/pattern_9

Significance: 0.0237088

Absent
WHL_BRN;8wks;D;GEO

Pattern: metacluster_1/pattern_18

Significance: 0.0507983

Absent
wES;WHL_BRN;E14.5;D;GEO

Pattern: metacluster_0/pattern_6

Significance: 0.0210546

Absent
ES;E14;D;En

Pattern: metacluster_1/pattern_5

Significance: 0.039042

Absent
FBRBLST;8wks;D;En

Pattern: metacluster_1/pattern_11

Significance: 0.0074639

Absent
ES;J1;A;CL

Pattern: metacluster_1/pattern_4

Significance: 0.00316364

Absent
ES;E14;A;GEO

Pattern: metacluster_0/pattern_10

Significance: 0.038549099999999996

Absent
ES;F1216;A;GEO

Pattern: metacluster_0/pattern_7

Significance: 0.00203124

Absent
ES;129SV_Jae_C57BL6J;A;GEO

Pattern: metacluster_1/pattern_6

Significance: 0.015140200000000001

Absent
ES;v6.5;A;GEO

Pattern: metacluster_1/pattern_13

Significance: 0.0344262

Absent
Mammary_GLND;A;GEO

Pattern: metacluster_1/pattern_9

Significance: 0.00681352

Absent
CRBL_GRNL_Precrsr;A;GEO

Pattern: metacluster_0/pattern_15

Significance: 0.0409972

Absent
Adipose;D;En

Pattern: metacluster_0/pattern_19

Significance: 0.00131923

Absent
RTN;D1;D;En

Pattern: metacluster_0/pattern_5

Significance: 0.0034955

Absent
wES;MSDRM;E11.5;D;En

Pattern: metacluster_0/pattern_3

Significance: 0.0161301

/

Pattern: metacluster_0/pattern_11

Significance: 0.0439421

Absent
Muller;P12;D;En

Pattern: metacluster_1/pattern_7

Significance: 0.00667259

Absent
wES.Fr_BRN;E14.4;D;En

Pattern: metacluster_0/pattern_8

Significance: 0.0184473

Absent
Fr_BRN;P0;D;En

Pattern: metacluster_1/pattern_6

Significance: 0.0156827

Absent
Hnd_BRN;P0;D;En

Pattern: metacluster_1/pattern_12

Significance: 0.0128161

Absent
wES;Hnd_BRN;E14.5;D;En

Pattern: metacluster_0/pattern_4

Significance: 0.00994247

Absent
wES;Md_BRN;E14.4;D;En

Pattern: metacluster_0/pattern_2

Significance: 0.0165352

Absent
Md_BRN;D;En

Pattern: metacluster_1/pattern_7

Significance: 0.016016100000000002

Absent
wES;WHL_BRN;E14.5;D;En

Pattern: metacluster_1/pattern_3

Significance: 0.00438866

Absent
WHL_BRN;8wks;D;En

Pattern: metacluster_1/pattern_15

Significance: 0.0135286

Absent
wES;Telenchephalon;D;En

Pattern: metacluster_1/pattern_17

Significance: 0.0271597

Absent
No Cell types only Homer finds Sox4