In [1]:
# Parameters
data_name = "Irf6"
task_idxs = "0-213,216-278"
homer_root = "/srv/scratch/msharmin/mouse_hem/with_tfd/full_mouse50/Naive_scans"
modisco_root = "/srv/scratch/msharmin/mouse_hem/with_tfd/full_mouse50/Naive_modisco2019"
overwrite = False
In [2]:
from matlas.reports import collect_motifDB_to_be_displayed, display_comparative_cell_types

load data from labcluster

Using TensorFlow backend.
2019-08-23 11:14:13,297 [WARNING] git-lfs not installed
In [3]:
homer_matches, modisco_matches = collect_motifDB_to_be_displayed(task_idxs, homer_root, modisco_root, 
                                                              overwrite=False)

TF-MoDISco is using the TensorFlow backend.
In [4]:
display_comparative_cell_types(data_name, homer_matches, modisco_matches)
Irf6: Motif: M00176_2.00



Forward PWM

Reverse PWM

Shared Cell types both TF-MoDISco and Homer finds Irf6: #5

Cell typeModiscoHomer
LNG;8wks;D;En

Pattern: metacluster_0/pattern_12

Significance: 0.0449449

Pattern: motif16.motif

Significance: 0.015287

LNG;P0;D;En

Pattern: metacluster_1/pattern_17

Significance: 0.0306916

Pattern: motif3.motif

Significance: 0.0441214

aB;CD180;A;CL

Pattern: metacluster_1/pattern_5

Significance: 0.04703

Pattern: motif3.motif

Significance: 0.0485718

gamma_delta_TCR_M-S-;A;CL

Pattern: metacluster_0/pattern_6

Significance: 0.0436972

Pattern: motif2.motif

Significance: 0.0358153

mem_precrsrT_SPLND;CD8+;A;GEO

Pattern: metacluster_1/pattern_4

Significance: 0.0279233

Pattern: motif7.motif

Significance: 0.014318700000000002

Unique Cell types only TF-MoDISco finds Irf6: #25

Cell typeModiscoHomer
wES;NRL_Tube;E11.5;D;En

Pattern: metacluster_1/pattern_25

Significance: 0.033236199999999994

Absent
STMCH;P0;D;En

Pattern: metacluster_1/pattern_13

Significance: 0.0112056

Absent
preB_BMD;A;GEO

Pattern: metacluster_1/pattern_4

Significance: 0.0483924

Absent
aB_LPS+IL4;A;CL

Pattern: metacluster_1/pattern_4

Significance: 0.05710610000000001

Absent
Mast;A;CL

Pattern: metacluster_0/pattern_12

Significance: 0.050429

Absent
ESNPHL_ex-vivo_BlbC;A;CL

Pattern: metacluster_0/pattern_12

Significance: 0.0205915

Absent
ESNPHL_SPLND_BlbCA;CL

Pattern: metacluster_0/pattern_10

Significance: 0.0297238

Absent
ROD_PHT_RCPTR_RTN;A;GEO

Pattern: metacluster_0/pattern_21

Significance: 0.035768400000000006

Absent
BCK_SKN;A;GEO

Pattern: metacluster_0/pattern_21

Significance: 0.055287

Absent
ES;MEF;A;CL

Pattern: metacluster_1/pattern_18

Significance: 0.041638999999999995

Absent
LNG;A;CL

Pattern: metacluster_1/pattern_15

Significance: 0.042370599999999994

Absent
Muscle;A;CL

Pattern: metacluster_1/pattern_20

Significance: 0.0297966

Absent
Heart;D;En

Pattern: metacluster_0/pattern_15

Significance: 0.022809700000000002

Absent
Mammary;A;CL

Pattern: metacluster_0/pattern_15

Significance: 0.023242099999999998

Absent
testis;A;CL

Pattern: metacluster_0/pattern_16

Significance: 0.0334594

Absent
placenta;A;CL

Pattern: metacluster_0/pattern_19

Significance: 0.058231399999999996

Absent
NRV;Eye-OPTC;A;CL

Pattern: metacluster_0/pattern_13

Significance: 0.0133799

Absent
BRN;OLFTRY_BLB;A;CL

Pattern: metacluster_0/pattern_18

Significance: 0.00917767

Absent
BRN;CRBLM;A;CL

Pattern: metacluster_0/pattern_13

Significance: 0.0435769

Absent
gamma_delta_TCR;A;CL

Pattern: metacluster_1/pattern_5

Significance: 0.031078500000000002

Absent
aB_LPS+IL4_24h;A;CL

Pattern: metacluster_0/pattern_5

Significance: 0.0396359

Absent
wCH12_drug;A;CL

Pattern: metacluster_1/pattern_8

Significance: 0.0529094

Absent
wES;LVR;E11.5;D.;En

Pattern: metacluster_1/pattern_22

Significance: 0.0141446

Absent
wES;LNG;E14.5;D;En

Pattern: metacluster_1/pattern_19

Significance: 0.0176641

Absent
Heart;8wks;D;En

Pattern: metacluster_0/pattern_15

Significance: 0.0422796

Absent
Unique Cell types only Homer finds Irf6: #24

Cell typeModiscoHomer
T_MLD;TCR_SV40-I_CD8+;D28;A;GEOAbsent

Pattern: motif6.motif

Significance: 0.016159299999999998

memT;CD4+;A;CLAbsent

Pattern: motif2.motif

Significance: 0.042099300000000006

memT_tmrD_lstr;TCR_SV40-I_CD8+;D14;A;GEOAbsent

Pattern: motif10.motif

Significance: 0.031549

iNKT;A;GEOAbsent

Pattern: motif9.motif

Significance: 0.0373914

Tfh_LCMV;A;CLAbsent

Pattern: motif2.motif

Significance: 0.026092400000000005

aNonTfh;A;CLAbsent

Pattern: motif2.motif

Significance: 0.0482175

aNonTfh_mut;A;CLAbsent

Pattern: motif2.motif

Significance: 0.0178467

Tfr_mut;CD4+CD44+CXCR5+PD1+CD25+;A;CLAbsent

Pattern: motif2.motif

Significance: 0.047956099999999995

naiveT;CD4+_CD44-_CD62L-_CD25-;A;CLAbsent

Pattern: motif2.motif

Significance: 0.0366449

naiveT_mut;CD4+_CD44-_CD62L-_CD25-;A;CLAbsent

Pattern: motif2.motif

Significance: 0.0292329

smallDPprecrsor;CD4+CD8+CD69-;A;CLAbsent

Pattern: motif2.motif

Significance: 0.0455617

CD4+CD8-TCR+CD69+CD24+CD25-;B2defM;A;CLAbsent

Pattern: motif2.motif

Significance: 0.0456645

CD4+CD8-TCR+CD25+Foxp3-;A;CLAbsent

Pattern: motif15.motif

Significance: 0.0580731

CD4+CD8-TCR+CD25-Foxp3+;A;CLAbsent

Pattern: motif2.motif

Significance: 0.0367418

CD4+CD8-TCR+CD25+Foxp3+;A;CLAbsent

Pattern: motif6.motif

Significance: 0.0456457

DP;A;CLAbsent

Pattern: motif2.motif

Significance: 0.027464799999999998

ThMS_MEC;Aire++;A;GEOAbsent

Pattern: motif8.motif

Significance: 0.036453

restingB;A;CLAbsent

Pattern: motif3.motif

Significance: 0.0582323

NCR+ILC3+IL23;A;CLAbsent

Pattern: motif13.motif

Significance: 0.050186699999999994

ILC2;A;CLAbsent

Pattern: motif2.motif

Significance: 0.055530600000000006

NK_LVRD;CD19-CD3e-NKp46+DX+Trail-;A;GEOAbsent

Pattern: motif5.motif

Significance: 0.014495699999999999

ILC3;A;GEOAbsent

Pattern: motif8.motif

Significance: 0.0123398

TSLEC_SPLND;CD8+A;GEOAbsent

Pattern: motif9.motif

Significance: 0.00790914

T_MLD;TCR_SV40-I_CD8+;D21;A;GEOAbsent

Pattern: motif7.motif

Significance: 0.011317200000000001