In [1]:
# Parameters
data_name = "Gata2"
task_idxs = "0-213,216-278"
homer_root = "/srv/scratch/msharmin/mouse_hem/with_tfd/full_mouse50/Naive_scans"
modisco_root = "/srv/scratch/msharmin/mouse_hem/with_tfd/full_mouse50/Naive_modisco2019"
overwrite = False
In [2]:
from matlas.reports import collect_motifDB_to_be_displayed, display_comparative_cell_types

load data from labcluster

Using TensorFlow backend.
2019-08-23 11:09:49,500 [WARNING] git-lfs not installed
In [3]:
homer_matches, modisco_matches = collect_motifDB_to_be_displayed(task_idxs, homer_root, modisco_root, 
                                                              overwrite=False)

TF-MoDISco is using the TensorFlow backend.
In [4]:
display_comparative_cell_types(data_name, homer_matches, modisco_matches)
Gata2: Motif: M09121_2.00



Forward PWM

Reverse PWM

Shared Cell types both TF-MoDISco and Homer finds Gata2: #19

Cell typeModiscoHomer
MegP;A;En

Pattern: metacluster_1/pattern_6

Significance: 8.81725e-05

Pattern: motif7.motif

Significance: 0.0199889

pCMP;A;CL

Pattern: metacluster_1/pattern_5

Significance: 0.000120291

Pattern: motif7.motif

Significance: 0.00708975

LVR;P0;D;En

Pattern: metacluster_1/pattern_7

Significance: 0.00306285

Pattern: motif13.motif

Significance: 0.0015115

wES;LVR;E11.5;D.;En

Pattern: metacluster_1/pattern_5

Significance: 0.00587196

Pattern: motif3.motif

Significance: 0.00267104

SKN_EPTHL;A;GEO

Pattern: metacluster_0/pattern_6

Significance: 0.000171281

Pattern: motif14.motif

Significance: 0.0312132

Heart;P0;D;En

Pattern: metacluster_1/pattern_13

Significance: 1.2791e-06

Pattern: motif13.motif

Significance: 0.0009592610000000001

STMCH;P0;D;En

Pattern: metacluster_1/pattern_17

Significance: 0.000192681

Pattern: motif13.motif

Significance: 0.05758919999999999

LNG_TRM_HSC;A;CL

Pattern: metacluster_1/pattern_10

Significance: 0.00025077

Pattern: motif14.motif

Significance: 0.0452765

416B;HMTP_SPNSN;CD34+;D;En

Pattern: metacluster_1/pattern_11

Significance: 2.5381e-06

Pattern: motif11.motif

Significance: 0.0115936

Erythroid;Ter119+;A;GEO

Pattern: metacluster_0/pattern_7

Significance: 0.00413452

Pattern: motif8.motif

Significance: 0.000267705

AML;AE9a;A;GEO

Pattern: metacluster_1/pattern_3

Significance: 1.3186300000000001e-05

Pattern: motif3.motif

Significance: 0.000134467

Mast;A;CL

Pattern: metacluster_0/pattern_7

Significance: 2.77427e-05

Pattern: motif6.motif

Significance: 0.000397235

BSPHL;A;CL

Pattern: metacluster_1/pattern_8

Significance: 3.58763e-05

Pattern: motif7.motif

Significance: 1.2641700000000001e-05

416B_MP;CD34+;D;GEO

Pattern: metacluster_1/pattern_12

Significance: 2.88396e-05

Pattern: motif12.motif

Significance: 0.0154953

EP;c-kit+CD71+Ter119+;D;En

Pattern: metacluster_1/pattern_8

Significance: 0.00770678

Pattern: motif5.motif

Significance: 0.0217265

416B_MP;CD34+;D;En

Pattern: metacluster_1/pattern_13

Significance: 3.57476e-05

Pattern: motif9.motif

Significance: 0.017726

MEF.GATA-1-ER;D;En

Pattern: metacluster_1/pattern_9

Significance: 0.00423063

Pattern: motif4.motif

Significance: 0.00790946

MEL;D;En

Pattern: metacluster_1/pattern_7

Significance: 4.46975e-05

Pattern: motif4.motif

Significance: 6.282829999999999e-07

MegEP;A;CL

Pattern: metacluster_1/pattern_2

Significance: 0.0006231580000000001

Pattern: motif2.motif

Significance: 1.5261e-05

Unique Cell types only TF-MoDISco finds Gata2: #41

Cell typeModiscoHomer
proB;A;CL

Pattern: metacluster_1/pattern_11

Significance: 0.00600526

Absent
iNKT;A;GEO

Pattern: metacluster_1/pattern_19

Significance: 0.00521405

Absent
B;B220_CD43;A;GEO

Pattern: metacluster_1/pattern_24

Significance: 0.0020706999999999995

Absent
ESNPHL_ex-vivo_BlbC;A;CL

Pattern: metacluster_0/pattern_18

Significance: 0.00014345299999999998

Absent
ESNPHL_SPLND_BlbCA;CL

Pattern: metacluster_0/pattern_15

Significance: 1.3955599999999999e-05

Absent
ENDRM_ESD;A;GEO

Pattern: metacluster_1/pattern_13

Significance: 7.9691e-08

Absent
MTR_NRN_MN1;methyl3;D;En

Pattern: metacluster_0/pattern_14

Significance: 0.00205139

Absent
MN1;D;En

Pattern: metacluster_1/pattern_20

Significance: 0.00482364

Absent
aNonTfh;A;CL

Pattern: metacluster_1/pattern_20

Significance: 0.0152119

Absent
Tfr_mut;CD4+CD44+CXCR5+PD1+CD25+;A;CL

Pattern: metacluster_1/pattern_20

Significance: 0.00295287

Absent
wES;5th_Rhmbmr;E8.5;A;GEO

Pattern: metacluster_0/pattern_26

Significance: 3.8893300000000006e-07

Absent
CD4+CD8intTCR+CD69+CD24+;B2defM;A;CL

Pattern: metacluster_1/pattern_16

Significance: 0.00453237

Absent
npES;posterior_delA;E8.5;A;GEO

Pattern: metacluster_0/pattern_18

Significance: 3.19498e-07

Absent
BCK_SKN;A;GEO

Pattern: metacluster_0/pattern_19

Significance: 0.00522549

Absent
Erythroblast;A;CL

Pattern: metacluster_1/pattern_9

Significance: 0.00021865

Absent
SML_INTSTN;A;CL

Pattern: metacluster_0/pattern_16

Significance: 2.1020500000000003e-05

Absent
LRG_INTSTN;A;CL

Pattern: metacluster_0/pattern_12

Significance: 5.52983e-06

Absent
Heart;D;En

Pattern: metacluster_0/pattern_17

Significance: 1.28072e-05

Absent
placenta;A;CL

Pattern: metacluster_0/pattern_17

Significance: 0.000113566

Absent
EPP;A;En

Pattern: metacluster_1/pattern_9

Significance: 0.00348398

Absent
STMCH;A;CL

Pattern: metacluster_1/pattern_23

Significance: 0.0341394

Absent
pErythroblast;A;En

Pattern: metacluster_1/pattern_9

Significance: 0.00297866

Absent
LVR;8wks;D;GEO

Pattern: metacluster_1/pattern_19

Significance: 0.000126539

Absent
LNG;8wks;D;GEO

Pattern: metacluster_0/pattern_22

Significance: 2.18835e-06

Absent
SHRT_TRM_HSC;A;CL

Pattern: metacluster_1/pattern_14

Significance: 0.00011075600000000001

Absent
T_SPLND_blstCLTRD;CD4+;D;GEO

Pattern: metacluster_1/pattern_13

Significance: 0.00118051

Absent
apCD4Eff;D;GEO

Pattern: metacluster_1/pattern_16

Significance: 0.00242891

Absent
ILC2precrsr;A;CL

Pattern: metacluster_1/pattern_6

Significance: 0.00456395

Absent
NCR+ILC3;A;CL

Pattern: metacluster_1/pattern_18

Significance: 0.00279298

Absent
ILC2_Nippo;A;CL

Pattern: metacluster_1/pattern_10

Significance: 0.00226441

Absent
NCR+ILC3+IL23;A;CL

Pattern: metacluster_1/pattern_16

Significance: 1.82762e-05

Absent
ILC2;A;CL

Pattern: metacluster_1/pattern_5

Significance: 8.93134e-05

Absent
Th2_nippo;A;CL

Pattern: metacluster_1/pattern_10

Significance: 0.00044055900000000004

Absent
LNG;8wks;D;En

Pattern: metacluster_0/pattern_22

Significance: 1.20744e-06

Absent
Heart;8wks;D;En

Pattern: metacluster_0/pattern_18

Significance: 4.61057e-06

Absent
Adipose;D;En

Pattern: metacluster_0/pattern_24

Significance: 0.0482961

Absent
ILC2+IL33+IL25;A;GEO

Pattern: metacluster_1/pattern_9

Significance: 0.000137911

Absent
ILC2;A;GEO

Pattern: metacluster_1/pattern_10

Significance: 0.00861308

Absent
ILC3;A;GEO

Pattern: metacluster_1/pattern_19

Significance: 4.95992e-05

Absent
abTreg;CD4+_CD25+;8wks;D;En

Pattern: metacluster_1/pattern_16

Significance: 0.013819

Absent
ILC2_AbxGRMFree;A;GEO

Pattern: metacluster_1/pattern_14

Significance: 0.00021019099999999998

Absent
Unique Cell types only Homer finds Gata2: #1

Cell typeModiscoHomer
MEL_Znc_di-cl;24h;D;EnAbsent

Pattern: motif6.motif

Significance: 0.0138071