In [1]:
# Parameters
data_name = "Ascl2"
task_idxs = "0-213,216-278"
homer_root = "/srv/scratch/msharmin/mouse_hem/with_tfd/full_mouse50/Naive_scans"
modisco_root = "/srv/scratch/msharmin/mouse_hem/with_tfd/full_mouse50/Naive_modisco2019"
overwrite = False
In [2]:
from matlas.reports import collect_motifDB_to_be_displayed, display_comparative_cell_types

load data from labcluster

Using TensorFlow backend.
2019-08-23 10:57:28,793 [WARNING] git-lfs not installed
In [3]:
homer_matches, modisco_matches = collect_motifDB_to_be_displayed(task_idxs, homer_root, modisco_root, 
                                                              overwrite=False)

TF-MoDISco is using the TensorFlow backend.
In [4]:
display_comparative_cell_types(data_name, homer_matches, modisco_matches)
Ascl2: Motif: M08744_2.00



Forward PWM

Reverse PWM

Shared Cell types both TF-MoDISco and Homer finds Ascl2: #33

Cell typeModiscoHomer
wES;limb;E14.5;D;En

Pattern: metacluster_1/pattern_1

Significance: 0.05664119999999999

Pattern: motif5.motif

Significance: 0.0009455010000000001

wES;limb;E11.5;D;En

Pattern: metacluster_0/pattern_6

Significance: 0.00561416

Pattern: motif12.motif

Significance: 0.052213999999999997

wES;FaceP;E14.5;D;En

Pattern: metacluster_0/pattern_1

Significance: 0.020716299999999997

Pattern: motif5.motif

Significance: 0.00189872

proB;A;CL

Pattern: metacluster_1/pattern_3

Significance: 0.00020194900000000001

Pattern: motif15.motif

Significance: 0.0371213

preB;A;CL

Pattern: metacluster_1/pattern_4

Significance: 0.000188536

Pattern: motif12.motif

Significance: 0.029691500000000003

wES;NRL_Tube;E11.5;D;En

Pattern: metacluster_1/pattern_5

Significance: 0.00132614

Pattern: motif15.motif

Significance: 0.0241832

SKLTL_Muscle;8wks;D;En

Pattern: metacluster_1/pattern_12

Significance: 0.0036209000000000002

Pattern: motif10.motif

Significance: 0.015125

prePLSM_B;A;GEO

Pattern: metacluster_1/pattern_20

Significance: 0.00784307

Pattern: motif22.motif

Significance: 0.046882599999999996

plasmaB;A;CL

Pattern: metacluster_1/pattern_5

Significance: 0.00026624

Pattern: motif9.motif

Significance: 0.042888699999999995

preB_BMD;A;GEO

Pattern: metacluster_1/pattern_5

Significance: 4.1499700000000005e-05

Pattern: motif9.motif

Significance: 0.00020936400000000002

B;B220_CD43;A;GEO

Pattern: metacluster_1/pattern_9

Significance: 6.80293e-05

/

Pattern: metacluster_1/pattern_18

Significance: 0.0480864

Pattern: motif11.motif

Significance: 0.0284198

largeDPprecrsr;CD4+CD8+CD69-;A;CL

Pattern: metacluster_1/pattern_5

Significance: 0.00219487

Pattern: motif18.motif

Significance: 0.0415592

smallDPprecrsor;CD4+CD8+CD69-;A;CL

Pattern: metacluster_1/pattern_4

Significance: 0.00548716

Pattern: motif13.motif

Significance: 0.0372527

NPC;F129;A;GEO

Pattern: metacluster_1/pattern_5

Significance: 0.00454242

Pattern: motif10.motif

Significance: 0.0159364

NPC;G4;A;GEO

Pattern: metacluster_1/pattern_5

Significance: 0.00244065

Pattern: motif9.motif

Significance: 0.000551766

NPC;Ch13;A;GEO

Pattern: metacluster_1/pattern_9

Significance: 0.00347651

Pattern: motif13.motif

Significance: 0.00689822

NPC;mE6;A;GEO

Pattern: metacluster_1/pattern_7

Significance: 0.00043653699999999997

Pattern: motif11.motif

Significance: 0.0115942

DP;A;CL

Pattern: metacluster_1/pattern_10

Significance: 0.00614442

Pattern: motif17.motif

Significance: 0.053396900000000004

ISP;A;CL

Pattern: metacluster_1/pattern_4

Significance: 2.91808e-05

Pattern: motif14.motif

Significance: 0.026755

eCortical_NRN;A;GEO

Pattern: metacluster_1/pattern_3

Significance: 0.0313766

Pattern: motif4.motif

Significance: 0.040052

Muscle;A;CL

Pattern: metacluster_1/pattern_16

Significance: 0.00190421

Pattern: motif19.motif

Significance: 0.0571202

Heart;D;En

Pattern: metacluster_0/pattern_8

Significance: 0.0201797

Pattern: motif13.motif

Significance: 0.054621800000000005

BRN;SNSR_MTR_CRTX;A;CL

Pattern: metacluster_1/pattern_6

Significance: 0.0586231

Pattern: motif7.motif

Significance: 0.024844

KDNY;P0;D;En

Pattern: metacluster_1/pattern_9

Significance: 0.042651999999999995

Pattern: motif15.motif

Significance: 0.039407

LNG;P0;D;En

Pattern: metacluster_1/pattern_11

Significance: 0.0348297

Pattern: motif18.motif

Significance: 0.010174299999999999

wES;LNG;E14.5;D;En

Pattern: metacluster_1/pattern_6

Significance: 0.0493116

Pattern: motif13.motif

Significance: 0.00840535

CRBL_GRNL_Precrsr;A;GEO

Pattern: metacluster_0/pattern_0

Significance: 0.0126471

Pattern: motif2.motif

Significance: 0.00532083

RTN;D1;D;En

Pattern: metacluster_0/pattern_4

Significance: 0.00043172699999999997

Pattern: motif16.motif

Significance: 0.013178

wES;MSDRM;E11.5;D;En

Pattern: metacluster_0/pattern_1

Significance: 0.00805674

Pattern: motif4.motif

Significance: 0.00787646

wES.Fr_BRN;E14.4;D;En

Pattern: metacluster_0/pattern_4

Significance: 0.018045500000000003

Pattern: motif11.motif

Significance: 0.017396400000000003

Fr_BRN;P0;D;En

Pattern: metacluster_1/pattern_15

Significance: 0.00133614

Pattern: motif7.motif

Significance: 0.0248193

wES;Md_BRN;E11.5;D;En

Pattern: metacluster_0/pattern_4

Significance: 0.00629364

Pattern: motif19.motif

Significance: 0.0373476

WHL_BRN;8wks;D;En

Pattern: metacluster_1/pattern_4

Significance: 0.0412116

/

Pattern: metacluster_1/pattern_11

Significance: 0.0176842

Pattern: motif2.motif

Significance: 0.0339913

Unique Cell types only TF-MoDISco finds Ascl2: #45

Cell typeModiscoHomer
wES;Fr_lmb;E11.5;D;En

Pattern: metacluster_1/pattern_3

Significance: 0.026837599999999996

Absent
B1_B;A;CL

Pattern: metacluster_1/pattern_18

Significance: 0.04648819999999999

/

Pattern: metacluster_1/pattern_19

Significance: 0.0345565

Absent
MTR_NRN_MN1;methyl3;D;En

Pattern: metacluster_0/pattern_12

Significance: 0.0462225

Absent
MN1;D;En

Pattern: metacluster_1/pattern_16

Significance: 0.0454603

Absent
GCN_PHT_RCPTR;A;GEO

Pattern: metacluster_1/pattern_13

Significance: 0.0506879

Absent
BL_CN_PHT_RCPTR;A;GEO

Pattern: metacluster_1/pattern_12

Significance: 0.0313468

Absent
CN_PHT_RCPTR;A;GEO

Pattern: metacluster_1/pattern_13

Significance: 0.017409

Absent
npES;3rd_Rhmbmr_delA;E8.5;A;GEO

Pattern: metacluster_0/pattern_24

Significance: 0.05041369999999999

Absent
wES;3rd_Rhmbmr;E8.5;A;GEO

Pattern: metacluster_0/pattern_10

Significance: 0.00111234

Absent
npES;5th_Rhmbmr_delC;E8.5;A;GEO

Pattern: metacluster_1/pattern_21

Significance: 0.0259594

Absent
wES;5th_Rhmbmr;E9.5;A;GEO

Pattern: metacluster_0/pattern_15

Significance: 8.904440000000001e-05

/

Pattern: metacluster_0/pattern_22

Significance: 0.049591

Absent
wES;5th_Rhmbmr;E8.5;A;GEO

Pattern: metacluster_0/pattern_12

Significance: 0.00363478

/

Pattern: metacluster_0/pattern_22

Significance: 0.0513558

Absent
npES;5th_Rhmbmr_delA;E8.5;A;GEO

Pattern: metacluster_0/pattern_5

Significance: 0.0452741

Absent
wES;posterior;1;E9.5;A;GEO

Pattern: metacluster_1/pattern_5

Significance: 0.011461399999999998

Absent
wES;posterior;2;E9.5;A;GEO

Pattern: metacluster_0/pattern_9

Significance: 0.000266427

Absent
wES;posterior;1;E8.5;A;GEO

Pattern: metacluster_0/pattern_10

Significance: 0.00176085

Absent
npES;posterior_delA;E8.5;A;GEO

Pattern: metacluster_0/pattern_8

Significance: 0.00249592

Absent
npES;posterior_delC;E8.5;A;GEO

Pattern: metacluster_0/pattern_9

Significance: 0.00425531

Absent
ePyramidal_NRN;A;GEO

Pattern: metacluster_1/pattern_2

Significance: 0.0580247

Absent
iPV_NRN;A;GEO

Pattern: metacluster_1/pattern_3

Significance: 0.0505649

Absent
DP3b;A;CL

Pattern: metacluster_1/pattern_3

Significance: 0.00430314

Absent
iVIP_NRN;A;GEO

Pattern: metacluster_1/pattern_0

Significance: 0.0542832

Absent
G_NRN_P;A;GEO

Pattern: metacluster_1/pattern_0

Significance: 0.023873099999999998

Absent
Corticotrope;A;GEO

Pattern: metacluster_0/pattern_17

Significance: 0.000101477

Absent
LNG;A;CL

Pattern: metacluster_1/pattern_20

Significance: 0.00173806

Absent
Melanotrope;A;GEO

Pattern: metacluster_0/pattern_8

Significance: 0.000309683

Absent
BRN;OLFTRY_BLB;A;CL

Pattern: metacluster_0/pattern_13

Significance: 0.00179519

Absent
BRN;FRNTL_CRTX;A;CL

Pattern: metacluster_1/pattern_12

Significance: 0.0519653

Absent
BRN;CRBLM;A;CL

Pattern: metacluster_0/pattern_7

Significance: 0.030789099999999996

Absent
LNG;8wks;D;GEO

Pattern: metacluster_0/pattern_21

Significance: 0.0521226

Absent
WHL_BRN;8wks;D;GEO

Pattern: metacluster_1/pattern_10

Significance: 0.00119183

Absent
wES;WHL_BRN;E14.5;D;GEO

Pattern: metacluster_0/pattern_2

Significance: 0.019853799999999998

Absent
wCH12_drug;A;CL

Pattern: metacluster_1/pattern_17

Significance: 0.000591276

Absent
LNG;8wks;D;En

Pattern: metacluster_0/pattern_17

Significance: 0.0338861

Absent
Heart;8wks;D;En

Pattern: metacluster_0/pattern_11

Significance: 0.032792400000000006

Absent
RTN;A;GEO

Pattern: metacluster_0/pattern_6

Significance: 0.012208799999999999

Absent
wES;RTN;E11.5;D;En

Pattern: metacluster_0/pattern_3

Significance: 0.00387334

Absent
CRBLM;D;En

Pattern: metacluster_1/pattern_1

Significance: 0.021581799999999998

Absent
Hnd_BRN;P0;D;En

Pattern: metacluster_1/pattern_3

Significance: 0.00656769

Absent
wES;Hnd_BRN;E11.5;D;En

Pattern: metacluster_0/pattern_4

Significance: 0.00279616

Absent
wES;Hnd_BRN;E14.5;D;En

Pattern: metacluster_0/pattern_7

Significance: 0.000733385

Absent
wES;Md_BRN;E14.4;D;En

Pattern: metacluster_0/pattern_4

Significance: 0.00474469

Absent
Md_BRN;D;En

Pattern: metacluster_1/pattern_5

Significance: 0.017989599999999998

Absent
wES;WHL_BRN;E14.5;D;En

Pattern: metacluster_1/pattern_5

Significance: 0.000803475

/

Pattern: metacluster_1/pattern_6

Significance: 0.046442699999999996

Absent
wES;Telenchephalon;D;En

Pattern: metacluster_1/pattern_3

Significance: 0.033100599999999994

Absent
Unique Cell types only Homer finds Ascl2: #3

Cell typeModiscoHomer
A20;B-lymphoma;D;EnAbsent

Pattern: motif13.motif

Significance: 0.0362904

wES;FaceP;E11.5;D;EnAbsent

Pattern: motif7.motif

Significance: 0.0532775

DP3a;A;CLAbsent

Pattern: motif12.motif

Significance: 0.00959585