In [1]:
# Parameters
data_name = "Ascl1"
task_idxs = "0-213,216-278"
homer_root = "/srv/scratch/msharmin/mouse_hem/with_tfd/full_mouse50/Naive_scans"
modisco_root = "/srv/scratch/msharmin/mouse_hem/with_tfd/full_mouse50/Naive_modisco2019"
overwrite = False
In [2]:
from matlas.reports import collect_motifDB_to_be_displayed, display_comparative_cell_types

load data from labcluster

Using TensorFlow backend.
2019-08-23 10:57:28,815 [WARNING] git-lfs not installed
In [3]:
homer_matches, modisco_matches = collect_motifDB_to_be_displayed(task_idxs, homer_root, modisco_root, 
                                                              overwrite=False)

TF-MoDISco is using the TensorFlow backend.
In [4]:
display_comparative_cell_types(data_name, homer_matches, modisco_matches)
Ascl1: Motif: M08748_2.00



Forward PWM

Reverse PWM

Shared Cell types both TF-MoDISco and Homer finds Ascl1: #29

Cell typeModiscoHomer
wES;limb;E11.5;D;En

Pattern: metacluster_0/pattern_6

Significance: 0.0483264

Pattern: motif12.motif

Significance: 0.055476599999999994

wES;FaceP;E14.5;D;En

Pattern: metacluster_0/pattern_1

Significance: 0.0389066

Pattern: motif5.motif

Significance: 0.000668694

proB;A;CL

Pattern: metacluster_1/pattern_3

Significance: 0.00386494

Pattern: motif15.motif

Significance: 0.0447655

preB;A;CL

Pattern: metacluster_1/pattern_4

Significance: 0.000748541

Pattern: motif12.motif

Significance: 0.0441852

wES;NRL_Tube;E11.5;D;En

Pattern: metacluster_1/pattern_5

Significance: 0.0157804

Pattern: motif15.motif

Significance: 0.0231393

SKLTL_Muscle;8wks;D;En

Pattern: metacluster_1/pattern_12

Significance: 0.030669

Pattern: motif10.motif

Significance: 0.047757

prePLSM_B;A;GEO

Pattern: metacluster_1/pattern_20

Significance: 0.0277177

Pattern: motif22.motif

Significance: 0.037337999999999996

plasmaB;A;CL

Pattern: metacluster_1/pattern_5

Significance: 0.0031644999999999998

Pattern: motif9.motif

Significance: 0.0211859

preB_BMD;A;GEO

Pattern: metacluster_1/pattern_5

Significance: 0.000741695

Pattern: motif9.motif

Significance: 0.0110289

B;B220_CD43;A;GEO

Pattern: metacluster_1/pattern_9

Significance: 0.000985574

/

Pattern: metacluster_1/pattern_18

Significance: 0.0480864

Pattern: motif11.motif

Significance: 0.054654999999999995

NPC;F129;A;GEO

Pattern: metacluster_1/pattern_5

Significance: 0.00454242

Pattern: motif10.motif

Significance: 0.026306200000000002

NPC;G4;A;GEO

Pattern: metacluster_1/pattern_5

Significance: 0.00194302

Pattern: motif9.motif

Significance: 0.00487407

NPC;Ch13;A;GEO

Pattern: metacluster_1/pattern_9

Significance: 0.00493079

Pattern: motif13.motif

Significance: 0.00997731

NPC;mE6;A;GEO

Pattern: metacluster_1/pattern_7

Significance: 0.00166986

Pattern: motif11.motif

Significance: 0.0115942

iPV_NRN;A;GEO

Pattern: metacluster_1/pattern_3

Significance: 0.00184636

Pattern: motif3.motif

Significance: 0.016744799999999997

ISP;A;CL

Pattern: metacluster_1/pattern_4

Significance: 0.001035

Pattern: motif14.motif

Significance: 0.039109500000000005

G_NRN_P;A;GEO

Pattern: metacluster_1/pattern_0

Significance: 0.0511291

Pattern: motif5.motif

Significance: 0.029681400000000004

Muscle;A;CL

Pattern: metacluster_1/pattern_16

Significance: 0.0202558

Pattern: motif19.motif

Significance: 0.056336000000000004

Heart;D;En

Pattern: metacluster_0/pattern_8

Significance: 0.040332400000000004

Pattern: motif13.motif

Significance: 0.020553000000000002

KDNY;P0;D;En

Pattern: metacluster_1/pattern_9

Significance: 0.050886400000000005

Pattern: motif15.motif

Significance: 0.057573599999999996

LNG;P0;D;En

Pattern: metacluster_1/pattern_11

Significance: 0.0493423

Pattern: motif18.motif

Significance: 0.00712961

CRBL_GRNL_Precrsr;A;GEO

Pattern: metacluster_0/pattern_0

Significance: 0.035700699999999995

Pattern: motif2.motif

Significance: 9.334939999999999e-06

RTN;D1;D;En

Pattern: metacluster_0/pattern_4

Significance: 0.0199604

Pattern: motif16.motif

Significance: 0.0207705

wES;MSDRM;E11.5;D;En

Pattern: metacluster_0/pattern_1

Significance: 0.000905346

Pattern: motif4.motif

Significance: 0.00153668

wES.Fr_BRN;E14.4;D;En

Pattern: metacluster_0/pattern_4

Significance: 0.00382625

Pattern: motif11.motif

Significance: 0.0075612

Fr_BRN;P0;D;En

Pattern: metacluster_1/pattern_15

Significance: 0.0264842

Pattern: motif7.motif

Significance: 0.0356722

wES;Md_BRN;E11.5;D;En

Pattern: metacluster_0/pattern_4

Significance: 0.0104798

Pattern: motif19.motif

Significance: 0.0117685

wES;WHL_BRN;E14.5;D;En

Pattern: metacluster_1/pattern_5

Significance: 0.00101168

/

Pattern: metacluster_1/pattern_6

Significance: 0.039148800000000004

Pattern: motif10.motif

Significance: 0.0179583

WHL_BRN;8wks;D;En

Pattern: metacluster_1/pattern_4

Significance: 0.027168400000000002

/

Pattern: metacluster_1/pattern_11

Significance: 0.0121899

Pattern: motif2.motif

Significance: 0.0414552

Unique Cell types only TF-MoDISco finds Ascl1: #48

Cell typeModiscoHomer
memT;CD4+;A;CL

Pattern: metacluster_1/pattern_22

Significance: 0.0504013

Absent
wES;Fr_lmb;E11.5;D;En

Pattern: metacluster_1/pattern_3

Significance: 0.014949700000000002

Absent
B1_B;A;CL

Pattern: metacluster_1/pattern_19

Significance: 0.0345565

Absent
Mast;A;CL

Pattern: metacluster_0/pattern_11

Significance: 0.05455019999999999

Absent
MTR_NRN_MN1;methyl3;D;En

Pattern: metacluster_0/pattern_12

Significance: 0.031558499999999996

Absent
MN1;D;En

Pattern: metacluster_1/pattern_16

Significance: 0.029279400000000004

Absent
GCN_PHT_RCPTR;A;GEO

Pattern: metacluster_1/pattern_13

Significance: 0.00902299

Absent
BL_CN_PHT_RCPTR;A;GEO

Pattern: metacluster_1/pattern_12

Significance: 0.03723030000000001

Absent
CN_PHT_RCPTR;A;GEO

Pattern: metacluster_1/pattern_13

Significance: 0.017409

Absent
wES;3rd_Rhmbmr;E8.5;A;GEO

Pattern: metacluster_0/pattern_10

Significance: 0.00924542

Absent
npES;5th_Rhmbmr_delC;E8.5;A;GEO

Pattern: metacluster_1/pattern_21

Significance: 0.0244431

Absent
wES;5th_Rhmbmr;E9.5;A;GEO

Pattern: metacluster_0/pattern_15

Significance: 0.0039352

Absent
largeDPprecrsr;CD4+CD8+CD69-;A;CL

Pattern: metacluster_1/pattern_5

Significance: 0.0037844000000000003

Absent
smallDPprecrsor;CD4+CD8+CD69-;A;CL

Pattern: metacluster_1/pattern_4

Significance: 0.00966459

Absent
wES;5th_Rhmbmr;E8.5;A;GEO

Pattern: metacluster_0/pattern_12

Significance: 0.039423

Absent
npES;5th_Rhmbmr_delA;E8.5;A;GEO

Pattern: metacluster_0/pattern_5

Significance: 0.0579643

Absent
wES;posterior;1;E9.5;A;GEO

Pattern: metacluster_1/pattern_5

Significance: 0.000141998

Absent
wES;posterior;2;E9.5;A;GEO

Pattern: metacluster_0/pattern_9

Significance: 0.019825799999999998

Absent
wES;posterior;1;E8.5;A;GEO

Pattern: metacluster_0/pattern_10

Significance: 0.0259443

Absent
npES;posterior_delA;E8.5;A;GEO

Pattern: metacluster_0/pattern_8

Significance: 0.00013022

Absent
npES;posterior_delC;E8.5;A;GEO

Pattern: metacluster_0/pattern_9

Significance: 0.0343984

Absent
DP;A;CL

Pattern: metacluster_1/pattern_10

Significance: 0.011750299999999998

Absent
ePyramidal_NRN;A;GEO

Pattern: metacluster_1/pattern_2

Significance: 0.023866099999999998

Absent
DP3b;A;CL

Pattern: metacluster_1/pattern_3

Significance: 0.010946

Absent
iVIP_NRN;A;GEO

Pattern: metacluster_1/pattern_0

Significance: 0.0522673

Absent
eCortical_NRN;A;GEO

Pattern: metacluster_1/pattern_3

Significance: 0.0280027

Absent
Corticotrope;A;GEO

Pattern: metacluster_0/pattern_5

Significance: 0.0586765

/

Pattern: metacluster_0/pattern_17

Significance: 0.00452775

Absent
LNG;A;CL

Pattern: metacluster_1/pattern_20

Significance: 0.00099943

Absent
Melanotrope;A;GEO

Pattern: metacluster_0/pattern_8

Significance: 0.00139484

Absent
BRN;OLFTRY_BLB;A;CL

Pattern: metacluster_0/pattern_13

Significance: 0.00179519

Absent
BRN;FRNTL_CRTX;A;CL

Pattern: metacluster_1/pattern_12

Significance: 0.031653

Absent
BRN;SNSR_MTR_CRTX;A;CL

Pattern: metacluster_1/pattern_6

Significance: 0.021315200000000003

Absent
BRN;CRBLM;A;CL

Pattern: metacluster_0/pattern_7

Significance: 0.0475142

Absent
WHL_BRN;8wks;D;GEO

Pattern: metacluster_1/pattern_2

Significance: 0.04693730000000001

/

Pattern: metacluster_1/pattern_10

Significance: 0.00242779

Absent
wES;WHL_BRN;E14.5;D;GEO

Pattern: metacluster_0/pattern_2

Significance: 0.047767199999999996

Absent
wCH12_drug;A;CL

Pattern: metacluster_1/pattern_17

Significance: 0.00270586

Absent
LNG;8wks;D;En

Pattern: metacluster_0/pattern_17

Significance: 0.044673000000000004

Absent
Heart;8wks;D;En

Pattern: metacluster_0/pattern_11

Significance: 0.0132296

Absent
RTN;A;GEO

Pattern: metacluster_0/pattern_6

Significance: 0.0147593

Absent
wES;RTN;E11.5;D;En

Pattern: metacluster_0/pattern_3

Significance: 0.011102899999999999

Absent
CRBLM;D;En

Pattern: metacluster_1/pattern_1

Significance: 0.0251562

Absent
naiveT;CD8+;A;GEO

Pattern: metacluster_1/pattern_14

Significance: 0.0451214

Absent
Hnd_BRN;P0;D;En

Pattern: metacluster_1/pattern_3

Significance: 0.015091

Absent
wES;Hnd_BRN;E11.5;D;En

Pattern: metacluster_0/pattern_4

Significance: 0.0171541

Absent
wES;Hnd_BRN;E14.5;D;En

Pattern: metacluster_0/pattern_7

Significance: 0.00103674

Absent
wES;Md_BRN;E14.4;D;En

Pattern: metacluster_0/pattern_4

Significance: 0.00718998

Absent
Md_BRN;D;En

Pattern: metacluster_1/pattern_5

Significance: 0.00271571

Absent
wES;Telenchephalon;D;En

Pattern: metacluster_1/pattern_3

Significance: 0.0230834

Absent
Unique Cell types only Homer finds Ascl1: #3

Cell typeModiscoHomer
wES;limb;E14.5;D;EnAbsent

Pattern: motif5.motif

Significance: 0.019468799999999998

wES;LNG;E14.5;D;EnAbsent

Pattern: motif13.motif

Significance: 0.028333999999999998

DP3a;A;CLAbsent

Pattern: motif12.motif

Significance: 0.0197804