In [1]:
# Parameters
data_name = "Cebpe"
task_idxs = "0-213,216-278"
homer_root = "/srv/scratch/msharmin/mouse_hem/with_tfd/full_mouse50/Naive_scans"
modisco_root = "/srv/scratch/msharmin/mouse_hem/with_tfd/full_mouse50/Naive_modisco2019"
overwrite = False
In [2]:
from matlas.reports import collect_motifDB_to_be_displayed, display_comparative_cell_types
load data from labcluster
Using TensorFlow backend.
2019-08-23 11:00:06,762 [WARNING] git-lfs not installed
In [3]:
homer_matches, modisco_matches = collect_motifDB_to_be_displayed(task_idxs, homer_root, modisco_root, 
                                                              overwrite=False)
TF-MoDISco is using the TensorFlow backend.
In [4]:
display_comparative_cell_types(data_name, homer_matches, modisco_matches)
Cebpe: Motif: M08836_2.00



Forward PWM

Reverse PWM

Shared Cell types both TF-MoDISco and Homer finds Cebpe: #40

Cell typeModiscoHomer
416B;HMTP_SPNSN;CD34+;D;En

Pattern: metacluster_1/pattern_4

Significance: 0.00828349

Pattern: motif6.motif

Significance: 0.014257399999999998

AML;D;En

Pattern: metacluster_1/pattern_2

Significance: 0.0108331

Pattern: motif3.motif

Significance: 0.000243405

MCRPHG_BMD.UnStmltd;A;GEO

Pattern: metacluster_1/pattern_7

Significance: 0.00167285

Pattern: motif11.motif

Significance: 0.000827049

MCRPHG_BMD.LPD_Stmltd;A;GEO

Pattern: metacluster_1/pattern_6

Significance: 0.012392100000000001

Pattern: motif10.motif

Significance: 0.00806914

DC_LPS;6h;A;GEO

Pattern: metacluster_1/pattern_4

Significance: 0.0194114

Pattern: motif5.motif

Significance: 0.0012214

/

Pattern: motif11.motif

Significance: 0.049469400000000004

BSPHL;A;CL

Pattern: metacluster_1/pattern_3

Significance: 0.00640504

Pattern: motif6.motif

Significance: 0.000463251

ESNPHL_ex-vivo_BlbC;A;CL

Pattern: metacluster_0/pattern_2

Significance: 0.0102375

Pattern: motif9.motif

Significance: 0.0217183

DC_LPS;2h;A;GEO

Pattern: metacluster_1/pattern_5

Significance: 0.0188762

Pattern: motif6.motif

Significance: 0.00122822

NTRPHL;A;CL

Pattern: metacluster_1/pattern_4

Significance: 0.0157049

Pattern: motif3.motif

Significance: 0.0343681

DC_pBMD;A;GEO

Pattern: metacluster_1/pattern_1

Significance: 0.0140937

Pattern: motif2.motif

Significance: 0.0169534

NIH3T3;D;En

Pattern: metacluster_1/pattern_4

Significance: 0.010640100000000001

Pattern: motif5.motif

Significance: 0.0006889999999999999

3T3-L1;D;En

Pattern: metacluster_1/pattern_9

Significance: 0.028773700000000003

Pattern: motif9.motif

Significance: 0.03675730000000001

DC_BMD;A;CL

Pattern: metacluster_1/pattern_7

Significance: 0.000768802

Pattern: motif11.motif

Significance: 0.00118959

MCRPHG;A;CL

Pattern: metacluster_1/pattern_5

Significance: 0.0140874

Pattern: motif7.motif

Significance: 0.0009075719999999999

Adrenal;A;CL

Pattern: metacluster_1/pattern_4

Significance: 0.019524400000000004

Pattern: motif7.motif

Significance: 0.000749903

Mammary_BptfKO;A;GEO

Pattern: metacluster_0/pattern_3

Significance: 0.0035400999999999996

Pattern: motif13.motif

Significance: 0.000634536

placenta;A;CL

Pattern: metacluster_0/pattern_8

Significance: 0.0115658

Pattern: motif9.motif

Significance: 0.0275053

pMeg;A;En

Pattern: metacluster_1/pattern_2

Significance: 0.0105794

Pattern: motif3.motif

Significance: 6.3215e-05

MegP;A;En

Pattern: metacluster_1/pattern_3

Significance: 0.023309599999999996

Pattern: motif4.motif

Significance: 0.000617996

pCMP;A;CL

Pattern: metacluster_1/pattern_11

Significance: 0.00759377

Pattern: motif9.motif

Significance: 0.0192577

DC_LPS;4h;A;En

Pattern: metacluster_1/pattern_5

Significance: 0.00291506

Pattern: motif6.motif

Significance: 0.00812723

pGMP;A;En

Pattern: metacluster_1/pattern_2

Significance: 0.00733784

Pattern: motif3.motif

Significance: 0.000208155

DC;A;En

Pattern: metacluster_1/pattern_5

Significance: 0.0174324

Pattern: motif5.motif

Significance: 9.213e-05

NIH3T3_FBROBLST;D;GEO

Pattern: metacluster_1/pattern_7

Significance: 0.00349334

Pattern: motif5.motif

Significance: 0.000555206

LVR;8wks;D;GEO

Pattern: metacluster_1/pattern_1

Significance: 0.012402700000000001

Pattern: motif3.motif

Significance: 0.000268388

LNG;8wks;D;GEO

Pattern: metacluster_0/pattern_2

Significance: 0.0133221

Pattern: motif3.motif

Significance: 0.00119101

416B_MP;CD34+;D;GEO

Pattern: metacluster_1/pattern_4

Significance: 0.00384607

Pattern: motif6.motif

Significance: 0.000587579

NIH3T3_FBROBLST;D;En

Pattern: metacluster_1/pattern_3

Significance: 0.00909036

Pattern: motif4.motif

Significance: 0.000250349

FBRBLST;8wks;D;En

Pattern: metacluster_1/pattern_3

Significance: 0.0164147

Pattern: motif6.motif

Significance: 0.000449285

LVR;8wks;D;En

Pattern: metacluster_0/pattern_2

Significance: 0.015452700000000002

Pattern: motif3.motif

Significance: 4.48141e-05

NTRPHL;A;GEO

Pattern: metacluster_0/pattern_3

Significance: 0.0245851

/

Pattern: metacluster_0/pattern_12

Significance: 0.00137413

Pattern: motif5.motif

Significance: 7.55801e-05

wES;LVR;E11.5;D.;En

Pattern: metacluster_1/pattern_9

Significance: 0.00511826

Pattern: motif15.motif

Significance: 0.0132621

LVR;P0;D;En

Pattern: metacluster_1/pattern_5

Significance: 0.00607455

Pattern: motif9.motif

Significance: 0.000859115

LNG;8wks;D;En

Pattern: metacluster_0/pattern_2

Significance: 0.014602

Pattern: motif2.motif

Significance: 0.000235917

LNG;P0;D;En

Pattern: metacluster_1/pattern_4

Significance: 0.008731399999999999

Pattern: motif4.motif

Significance: 0.00034285699999999996

Mammary_GLND;A;GEO

Pattern: metacluster_1/pattern_5

Significance: 0.00742201

Pattern: motif10.motif

Significance: 0.012872999999999999

Adipocyte_3T3-L1D;C57BL6;D8;D;En

Pattern: metacluster_1/pattern_1

Significance: 0.00992973

Pattern: motif2.motif

Significance: 0.000353461

Adipose;D;En

Pattern: metacluster_0/pattern_0

Significance: 0.0330464

/

Pattern: metacluster_0/pattern_1

Significance: 0.016669999999999997

Pattern: motif1.motif

Significance: 0.00011763399999999999

416B_MP;CD34+;D;En

Pattern: metacluster_1/pattern_4

Significance: 0.0031292

Pattern: motif6.motif

Significance: 0.000539757

Muller;P12;D;En

Pattern: metacluster_1/pattern_8

Significance: 0.034084699999999996

Pattern: motif15.motif

Significance: 0.0009759860000000001

Unique Cell types only TF-MoDISco finds Cebpe: #22

Cell typeModiscoHomer
MPP;A;CL

Pattern: metacluster_1/pattern_16

Significance: 0.00938405

Absent
SKLTL_Muscle;8wks;D;En

Pattern: metacluster_1/pattern_6

Significance: 0.031833

Absent
3134_mammaryADNCRCNM;D;En

Pattern: metacluster_0/pattern_12

Significance: 0.014475

Absent
MEL;D;En

Pattern: metacluster_1/pattern_16

Significance: 0.0208143

Absent
MEL_Znc_di-cl;24h;D;En

Pattern: metacluster_1/pattern_20

Significance: 0.0017362999999999999

Absent
MTR_NRN_MN1;methyl3;D;En

Pattern: metacluster_0/pattern_16

Significance: 0.0509482

/

Pattern: metacluster_0/pattern_17

Significance: 0.05902090000000001

Absent
ESNPHL_SPLND_BlbCA;CL

Pattern: metacluster_0/pattern_8

Significance: 0.00614202

Absent
SKN_EPTHL;A;GEO

Pattern: metacluster_0/pattern_11

Significance: 0.004517

Absent
BCK_SKN;A;GEO

Pattern: metacluster_0/pattern_14

Significance: 0.00142516

Absent
ES;MEF;A;CL

Pattern: metacluster_1/pattern_11

Significance: 0.029355400000000004

Absent
Corticotrope;A;GEO

Pattern: metacluster_0/pattern_21

Significance: 0.00126768

Absent
LNG;A;CL

Pattern: metacluster_1/pattern_8

Significance: 0.0136465

Absent
Muscle;A;CL

Pattern: metacluster_1/pattern_11

Significance: 0.0176832

Absent
Heart;D;En

Pattern: metacluster_0/pattern_12

Significance: 0.00469509

Absent
Mammary;A;CL

Pattern: metacluster_0/pattern_11

Significance: 0.0253405

Absent
BRN;FRNTL_CRTX;A;CL

Pattern: metacluster_1/pattern_19

Significance: 0.0408574

Absent
BRN;PTMN;A;CL

Pattern: metacluster_1/pattern_21

Significance: 0.059602999999999996

Absent
3134_mammaryADNCRCNM;D;GE

Pattern: metacluster_1/pattern_14

Significance: 0.021092

Absent
3T3-L1;FBRBLST;D;En

Pattern: metacluster_1/pattern_9

Significance: 0.027476

Absent
KDNY;8wks;D;En

Pattern: metacluster_1/pattern_12

Significance: 0.0329246

Absent
wES;LNG;E14.5;D;En

Pattern: metacluster_1/pattern_12

Significance: 0.00122203

Absent
Heart;8wks;D;En

Pattern: metacluster_0/pattern_10

Significance: 0.00191948

Absent
Unique Cell types only Homer finds Cebpe: #2

Cell typeModiscoHomer
restingB;A;CLAbsent

Pattern: motif15.motif

Significance: 0.0587057

aB_LPS+IL21;A;CLAbsent

Pattern: motif15.motif

Significance: 0.0557476