In [1]:
# Parameters
data_name = "Tcf21"
task_idxs = "0-213,216-278"
homer_root = "/srv/scratch/msharmin/mouse_hem/with_tfd/full_mouse50/Naive_scans"
modisco_root = "/srv/scratch/msharmin/mouse_hem/with_tfd/full_mouse50/Naive_modisco2019"
overwrite = False
In [2]:
from matlas.reports import collect_motifDB_to_be_displayed, display_comparative_cell_types

load data from labcluster

Using TensorFlow backend.
2019-08-23 11:42:25,105 [WARNING] git-lfs not installed
In [3]:
homer_matches, modisco_matches = collect_motifDB_to_be_displayed(task_idxs, homer_root, modisco_root, 
                                                              overwrite=False)

TF-MoDISco is using the TensorFlow backend.
In [4]:
display_comparative_cell_types(data_name, homer_matches, modisco_matches)
Tcf21: Motif: M02819_2.00



Forward PWM

Reverse PWM

Shared Cell types both TF-MoDISco and Homer finds Tcf21: #37

Cell typeModiscoHomer
wES;limb;E14.5;D;En

Pattern: metacluster_1/pattern_1

Significance: 0.0130232

Pattern: motif5.motif

Significance: 0.00020696

wES;limb;E11.5;D;En

Pattern: metacluster_0/pattern_6

Significance: 0.00561416

/

Pattern: metacluster_0/pattern_7

Significance: 0.042116100000000004

Pattern: motif12.motif

Significance: 0.046874400000000004

wES;Fr_lmb;E11.5;D;En

Pattern: metacluster_1/pattern_3

Significance: 0.014180799999999999

Pattern: motif6.motif

Significance: 0.0222502

wES;Hnd_lmb;E11.5;D;En

Pattern: metacluster_0/pattern_2

Significance: 0.0389655

Pattern: motif11.motif

Significance: 0.048824900000000004

wES;FaceP;E14.5;D;En

Pattern: metacluster_0/pattern_1

Significance: 0.0410005

Pattern: motif5.motif

Significance: 0.00109481

proB;A;CL

Pattern: metacluster_1/pattern_3

Significance: 0.00365131

Pattern: motif15.motif

Significance: 0.027501799999999996

preB;A;CL

Pattern: metacluster_1/pattern_4

Significance: 0.044007599999999994

Pattern: motif12.motif

Significance: 0.025872500000000003

wES;FaceP;E11.5;D;En

Pattern: metacluster_1/pattern_2

Significance: 0.0137363

Pattern: motif7.motif

Significance: 0.035414

wES;NRL_Tube;E11.5;D;En

Pattern: metacluster_1/pattern_5

Significance: 0.00692029

Pattern: motif15.motif

Significance: 0.0241832

SKLTL_Muscle;8wks;D;En

Pattern: metacluster_1/pattern_12

Significance: 0.0255789

Pattern: motif10.motif

Significance: 0.0324522

prePLSM_B;A;GEO

Pattern: metacluster_1/pattern_20

Significance: 0.0170757

Pattern: motif22.motif

Significance: 0.034938800000000006

plasmaB;A;CL

Pattern: metacluster_1/pattern_5

Significance: 0.051625800000000006

Pattern: motif9.motif

Significance: 0.0113916

preB_BMD;A;GEO

Pattern: metacluster_1/pattern_5

Significance: 0.012340100000000001

Pattern: motif9.motif

Significance: 0.029994

B;B220_CD43;A;GEO

Pattern: metacluster_1/pattern_9

Significance: 0.018102700000000003

Pattern: motif11.motif

Significance: 0.018524799999999998

3T3-L1;D;En

Pattern: metacluster_1/pattern_12

Significance: 0.0431836

Pattern: motif15.motif

Significance: 0.056063699999999994

ePyramidal_NRN;A;GEO

Pattern: metacluster_1/pattern_2

Significance: 0.00198918

Pattern: motif4.motif

Significance: 0.00138713

eCortical_NRN;A;GEO

Pattern: metacluster_1/pattern_3

Significance: 0.00329082

Pattern: motif4.motif

Significance: 0.000803223

G_NRN_P;A;GEO

Pattern: metacluster_1/pattern_0

Significance: 0.00451803

Pattern: motif5.motif

Significance: 0.0309927

/

Pattern: motif15.motif

Significance: 0.043247100000000004

Muscle;A;CL

Pattern: metacluster_1/pattern_16

Significance: 0.00369349

Pattern: motif19.motif

Significance: 0.021330500000000002

Heart;D;En

Pattern: metacluster_0/pattern_8

Significance: 0.0114646

Pattern: motif13.motif

Significance: 0.0192508

BRN;FRNTL_CRTX;A;CL

Pattern: metacluster_1/pattern_12

Significance: 0.00303067

Pattern: motif15.motif

Significance: 0.0009417989999999999

BRN;SNSR_MTR_CRTX;A;CL

Pattern: metacluster_1/pattern_6

Significance: 0.00365897

Pattern: motif7.motif

Significance: 0.00378886

BRN;CRBLM;A;CL

Pattern: metacluster_0/pattern_7

Significance: 0.00931554

Pattern: motif7.motif

Significance: 0.042650400000000005

WHL_BRN;8wks;D;GEO

Pattern: metacluster_1/pattern_2

Significance: 0.00430031

/

Pattern: metacluster_1/pattern_10

Significance: 0.0303171

Pattern: motif2.motif

Significance: 0.011592100000000001

wES;WHL_BRN;E14.5;D;GEO

Pattern: metacluster_0/pattern_2

Significance: 0.00532617

Pattern: motif13.motif

Significance: 0.00235794

KDNY;P0;D;En

Pattern: metacluster_1/pattern_9

Significance: 0.0502586

Pattern: motif15.motif

Significance: 0.0246565

LNG;P0;D;En

Pattern: metacluster_1/pattern_11

Significance: 0.047616399999999996

Pattern: motif18.motif

Significance: 0.0081999

wES;LNG;E14.5;D;En

Pattern: metacluster_1/pattern_6

Significance: 0.028576

Pattern: motif13.motif

Significance: 0.033272699999999995

CRBL_GRNL_Precrsr;A;GEO

Pattern: metacluster_0/pattern_0

Significance: 0.0412381

Pattern: motif2.motif

Significance: 0.026379700000000002

RTN;D1;D;En

Pattern: metacluster_0/pattern_4

Significance: 0.0352204

Pattern: motif16.motif

Significance: 0.0535591

wES;MSDRM;E11.5;D;En

Pattern: metacluster_0/pattern_1

Significance: 0.00142355

Pattern: motif4.motif

Significance: 0.030499099999999998

wES.Fr_BRN;E14.4;D;En

Pattern: metacluster_0/pattern_4

Significance: 0.00386533

Pattern: motif11.motif

Significance: 0.00239801

Fr_BRN;P0;D;En

Pattern: metacluster_1/pattern_4

Significance: 0.00335417

/

Pattern: metacluster_1/pattern_15

Significance: 0.0214356

Pattern: motif7.motif

Significance: 0.00175947

Hnd_BRN;P0;D;En

Pattern: metacluster_1/pattern_3

Significance: 0.00635107

Pattern: motif8.motif

Significance: 0.028760400000000005

wES;WHL_BRN;E14.5;D;En

Pattern: metacluster_1/pattern_6

Significance: 0.00439687

Pattern: motif10.motif

Significance: 0.026516200000000004

WHL_BRN;8wks;D;En

Pattern: metacluster_1/pattern_4

Significance: 0.00338792

Pattern: motif2.motif

Significance: 0.0202894

wES;Telenchephalon;D;En

Pattern: metacluster_1/pattern_3

Significance: 0.00205832

Pattern: motif4.motif

Significance: 0.035250800000000006

Unique Cell types only TF-MoDISco finds Tcf21: #36

Cell typeModiscoHomer
NIH3T3;D;En

Pattern: metacluster_1/pattern_8

Significance: 0.0159248

Absent
MTR_NRN_MN1;methyl3;D;En

Pattern: metacluster_0/pattern_12

Significance: 0.0487504

Absent
GCN_PHT_RCPTR;A;GEO

Pattern: metacluster_1/pattern_13

Significance: 0.0123666

Absent
BL_CN_PHT_RCPTR;A;GEO

Pattern: metacluster_1/pattern_12

Significance: 0.012298700000000001

Absent
CN_PHT_RCPTR;A;GEO

Pattern: metacluster_1/pattern_13

Significance: 0.0101008

Absent
wES;3rd_Rhmbmr;E8.5;A;GEO

Pattern: metacluster_0/pattern_10

Significance: 0.0179902

/

Pattern: metacluster_0/pattern_22

Significance: 0.030987

Absent
npES;5th_Rhmbmr_delC;E8.5;A;GEO

Pattern: metacluster_1/pattern_21

Significance: 0.024956799999999998

Absent
wES;5th_Rhmbmr;E9.5;A;GEO

Pattern: metacluster_0/pattern_15

Significance: 0.00477327

/

Pattern: metacluster_0/pattern_22

Significance: 0.00250015

/

Pattern: metacluster_0/pattern_24

Significance: 0.0149825

Absent
wES;5th_Rhmbmr;E8.5;A;GEO

Pattern: metacluster_0/pattern_12

Significance: 0.00640593

/

Pattern: metacluster_0/pattern_22

Significance: 0.022395500000000002

Absent
npES;5th_Rhmbmr_delA;E8.5;A;GEO

Pattern: metacluster_0/pattern_5

Significance: 0.0564985

Absent
wES;posterior;1;E9.5;A;GEO

Pattern: metacluster_1/pattern_5

Significance: 0.00824153

Absent
wES;posterior;2;E9.5;A;GEO

Pattern: metacluster_0/pattern_9

Significance: 0.000472465

Absent
wES;posterior;1;E8.5;A;GEO

Pattern: metacluster_0/pattern_10

Significance: 0.00577138

Absent
npES;posterior_delA;E8.5;A;GEO

Pattern: metacluster_0/pattern_8

Significance: 0.00123196

Absent
npES;posterior_delC;E8.5;A;GEO

Pattern: metacluster_0/pattern_9

Significance: 0.00425531

Absent
wES.CRNL_NRL_CRST;E10.5;A;GEO

Pattern: metacluster_0/pattern_5

Significance: 0.017681

Absent
NPC;mE6;A;GEO

Pattern: metacluster_1/pattern_7

Significance: 0.0436622

Absent
iPV_NRN;A;GEO

Pattern: metacluster_1/pattern_3

Significance: 0.0562696

Absent
ISP;A;CL

Pattern: metacluster_1/pattern_4

Significance: 0.0241647

Absent
Corticotrope;A;GEO

Pattern: metacluster_0/pattern_17

Significance: 0.00452775

Absent
LNG;A;CL

Pattern: metacluster_1/pattern_20

Significance: 0.048874400000000005

Absent
BRN;OLFTRY_BLB;A;CL

Pattern: metacluster_0/pattern_13

Significance: 0.0571362

Absent
NIH3T3_FBROBLST;D;GEO

Pattern: metacluster_1/pattern_9

Significance: 0.0332898

Absent
NIH3T3_FBROBLST;D;En

Pattern: metacluster_1/pattern_8

Significance: 0.018043599999999996

Absent
FBRBLST;8wks;D;En

Pattern: metacluster_1/pattern_15

Significance: 0.0554293

Absent
wCH12_drug;A;CL

Pattern: metacluster_1/pattern_17

Significance: 0.0461203

Absent
3T3-L1;FBRBLST;D;En

Pattern: metacluster_1/pattern_14

Significance: 0.0424763

Absent
LNG;8wks;D;En

Pattern: metacluster_0/pattern_17

Significance: 0.0206591

Absent
Heart;8wks;D;En

Pattern: metacluster_0/pattern_11

Significance: 0.027679900000000004

Absent
RTN;A;GEO

Pattern: metacluster_0/pattern_6

Significance: 0.0114589

Absent
wES;RTN;E11.5;D;En

Pattern: metacluster_0/pattern_3

Significance: 0.0433916

Absent
CRBLM;D;En

Pattern: metacluster_1/pattern_1

Significance: 0.010073

Absent
wES;Hnd_BRN;E11.5;D;En

Pattern: metacluster_0/pattern_4

Significance: 0.0094257

Absent
wES;Hnd_BRN;E14.5;D;En

Pattern: metacluster_0/pattern_12

Significance: 0.00577686

Absent
wES;Md_BRN;E11.5;D;En

Pattern: metacluster_0/pattern_4

Significance: 0.0531658

Absent
Md_BRN;D;En

Pattern: metacluster_1/pattern_5

Significance: 0.0117818

Absent
Unique Cell types only Homer finds Tcf21: #3

Cell typeModiscoHomer
NPC;F129;A;GEOAbsent

Pattern: motif10.motif

Significance: 0.0206951

NPC;Ch13;A;GEOAbsent

Pattern: motif13.motif

Significance: 0.0159378

DP3a;A;CLAbsent

Pattern: motif12.motif

Significance: 0.0264931