In [1]:
# Parameters
data_name = "Atoh1"
task_idxs = "0-213,216-278"
homer_root = "/srv/scratch/msharmin/mouse_hem/with_tfd/full_mouse50/Naive_scans"
modisco_root = "/srv/scratch/msharmin/mouse_hem/with_tfd/full_mouse50/Naive_modisco2019"
overwrite = False
In [2]:
from matlas.reports import collect_motifDB_to_be_displayed, display_comparative_cell_types
load data from labcluster
Using TensorFlow backend.
2019-08-23 10:58:13,986 [WARNING] git-lfs not installed
In [3]:
homer_matches, modisco_matches = collect_motifDB_to_be_displayed(task_idxs, homer_root, modisco_root, 
                                                              overwrite=False)
TF-MoDISco is using the TensorFlow backend.
In [4]:
display_comparative_cell_types(data_name, homer_matches, modisco_matches)
Atoh1: Motif: M08779_2.00



Forward PWM

Reverse PWM

Shared Cell types both TF-MoDISco and Homer finds Atoh1: #40

Cell typeModiscoHomer
wES;limb;E14.5;D;En

Pattern: metacluster_1/pattern_1

Significance: 0.0420713

Pattern: motif5.motif

Significance: 0.00129591

wES;limb;E11.5;D;En

Pattern: metacluster_0/pattern_6

Significance: 0.0148067

Pattern: motif12.motif

Significance: 0.0530845

wES;Fr_lmb;E11.5;D;En

Pattern: metacluster_1/pattern_3

Significance: 0.015485399999999998

Pattern: motif6.motif

Significance: 0.0565482

wES;FaceP;E14.5;D;En

Pattern: metacluster_0/pattern_1

Significance: 0.048110900000000005

Pattern: motif5.motif

Significance: 0.005372

proB;A;CL

Pattern: metacluster_1/pattern_3

Significance: 0.00637636

Pattern: motif15.motif

Significance: 0.0467884

preB;A;CL

Pattern: metacluster_1/pattern_4

Significance: 0.00382797

Pattern: motif12.motif

Significance: 0.034868

wES;FaceP;E11.5;D;En

Pattern: metacluster_1/pattern_2

Significance: 0.0550774

Pattern: motif7.motif

Significance: 0.054980499999999995

wES;NRL_Tube;E11.5;D;En

Pattern: metacluster_1/pattern_5

Significance: 0.013963

Pattern: motif15.motif

Significance: 0.0336151

SKLTL_Muscle;8wks;D;En

Pattern: metacluster_1/pattern_12

Significance: 0.03340119999999999

Pattern: motif10.motif

Significance: 0.026440699999999998

preB_BMD;A;GEO

Pattern: metacluster_1/pattern_5

Significance: 0.004901399999999999

Pattern: motif9.motif

Significance: 0.00578686

B;B220_CD43;A;GEO

Pattern: metacluster_1/pattern_9

Significance: 0.00684493

Pattern: motif11.motif

Significance: 0.037994400000000005

MTR_NRN_MN1;methyl3;D;En

Pattern: metacluster_0/pattern_12

Significance: 0.0462225

Pattern: motif10.motif

Significance: 0.0353035

3T3-L1;D;En

Pattern: metacluster_1/pattern_12

Significance: 0.05251619999999999

Pattern: motif15.motif

Significance: 0.056063699999999994

NPC;F129;A;GEO

Pattern: metacluster_1/pattern_5

Significance: 0.0116466

Pattern: motif10.motif

Significance: 0.0211572

NPC;G4;A;GEO

Pattern: metacluster_1/pattern_5

Significance: 0.00362525

Pattern: motif9.motif

Significance: 0.00507529

NPC;Ch13;A;GEO

Pattern: metacluster_1/pattern_9

Significance: 0.0296252

Pattern: motif13.motif

Significance: 0.00944001

NPC;mE6;A;GEO

Pattern: metacluster_1/pattern_7

Significance: 0.00537982

Pattern: motif11.motif

Significance: 0.018741099999999997

ePyramidal_NRN;A;GEO

Pattern: metacluster_1/pattern_2

Significance: 0.00107827

Pattern: motif4.motif

Significance: 0.016925400000000004

eCortical_NRN;A;GEO

Pattern: metacluster_1/pattern_3

Significance: 0.00121069

Pattern: motif4.motif

Significance: 0.00379565

G_NRN_P;A;GEO

Pattern: metacluster_1/pattern_0

Significance: 0.011631299999999999

Pattern: motif5.motif

Significance: 0.019644799999999997

/

Pattern: motif15.motif

Significance: 0.0253346

Muscle;A;CL

Pattern: metacluster_1/pattern_16

Significance: 0.0237036

Pattern: motif19.motif

Significance: 0.0362691

BRN;FRNTL_CRTX;A;CL

Pattern: metacluster_1/pattern_12

Significance: 0.00706569

Pattern: motif15.motif

Significance: 0.0393953

BRN;SNSR_MTR_CRTX;A;CL

Pattern: metacluster_1/pattern_6

Significance: 0.00922273

Pattern: motif7.motif

Significance: 0.00170297

BRN;CRBLM;A;CL

Pattern: metacluster_0/pattern_7

Significance: 0.0044845

Pattern: motif7.motif

Significance: 0.045477

WHL_BRN;8wks;D;GEO

Pattern: metacluster_1/pattern_2

Significance: 0.00746995

/

Pattern: metacluster_1/pattern_10

Significance: 0.00485099

Pattern: motif2.motif

Significance: 0.0149484

wES;WHL_BRN;E14.5;D;GEO

Pattern: metacluster_0/pattern_2

Significance: 0.0160636

Pattern: motif13.motif

Significance: 0.0192426

LNG;P0;D;En

Pattern: metacluster_1/pattern_11

Significance: 0.0348297

Pattern: motif18.motif

Significance: 0.0474267

Heart;8wks;D;En

Pattern: metacluster_0/pattern_11

Significance: 0.0142942

Pattern: motif11.motif

Significance: 0.04500440000000001

CRBL_GRNL_Precrsr;A;GEO

Pattern: metacluster_0/pattern_0

Significance: 0.0131967

Pattern: motif2.motif

Significance: 0.0011741

RTN;D1;D;En

Pattern: metacluster_0/pattern_4

Significance: 0.013191299999999998

Pattern: motif16.motif

Significance: 0.013178

wES;RTN;E11.5;D;En

Pattern: metacluster_0/pattern_3

Significance: 0.0288719

Pattern: motif14.motif

Significance: 0.0161852

wES;MSDRM;E11.5;D;En

Pattern: metacluster_0/pattern_1

Significance: 0.00362686

Pattern: motif4.motif

Significance: 0.0152844

wES.Fr_BRN;E14.4;D;En

Pattern: metacluster_0/pattern_4

Significance: 0.00269394

Pattern: motif11.motif

Significance: 0.000601061

Fr_BRN;P0;D;En

Pattern: metacluster_1/pattern_4

Significance: 0.01162

/

Pattern: metacluster_1/pattern_15

Significance: 0.0229053

Pattern: motif7.motif

Significance: 0.000882557

Hnd_BRN;P0;D;En

Pattern: metacluster_1/pattern_3

Significance: 0.028291300000000002

Pattern: motif8.motif

Significance: 0.0571092

wES;Md_BRN;E11.5;D;En

Pattern: metacluster_0/pattern_4

Significance: 0.0488336

Pattern: motif19.motif

Significance: 0.0275536

Md_BRN;D;En

Pattern: metacluster_1/pattern_5

Significance: 0.00774431

Pattern: motif15.motif

Significance: 0.0008345039999999999

wES;WHL_BRN;E14.5;D;En

Pattern: metacluster_1/pattern_5

Significance: 0.00582292

/

Pattern: metacluster_1/pattern_6

Significance: 0.009175399999999998

Pattern: motif10.motif

Significance: 0.023558199999999998

WHL_BRN;8wks;D;En

Pattern: metacluster_1/pattern_4

Significance: 0.0016822

/

Pattern: metacluster_1/pattern_11

Significance: 0.0163973

Pattern: motif2.motif

Significance: 0.013868200000000002

wES;Telenchephalon;D;En

Pattern: metacluster_1/pattern_3

Significance: 0.00108377

Pattern: motif4.motif

Significance: 0.0167893

Unique Cell types only TF-MoDISco finds Atoh1: #35

Cell typeModiscoHomer
prePLSM_B;A;GEO

Pattern: metacluster_1/pattern_20

Significance: 0.028562200000000003

Absent
plasmaB;A;CL

Pattern: metacluster_1/pattern_5

Significance: 0.0092976

Absent
NIH3T3;D;En

Pattern: metacluster_1/pattern_8

Significance: 0.05587999999999999

Absent
MN1;D;En

Pattern: metacluster_1/pattern_16

Significance: 0.0423956

Absent
GCN_PHT_RCPTR;A;GEO

Pattern: metacluster_1/pattern_13

Significance: 0.00466227

Absent
BL_CN_PHT_RCPTR;A;GEO

Pattern: metacluster_1/pattern_12

Significance: 0.00393104

Absent
CN_PHT_RCPTR;A;GEO

Pattern: metacluster_1/pattern_13

Significance: 0.00350207

Absent
wES;3rd_Rhmbmr;E8.5;A;GEO

Pattern: metacluster_0/pattern_10

Significance: 0.05550419999999999

/

Pattern: metacluster_0/pattern_22

Significance: 0.04364

Absent
npES;5th_Rhmbmr_delC;E8.5;A;GEO

Pattern: metacluster_1/pattern_21

Significance: 0.024956799999999998

Absent
wES;5th_Rhmbmr;E9.5;A;GEO

Pattern: metacluster_0/pattern_15

Significance: 0.038727

/

Pattern: metacluster_0/pattern_22

Significance: 0.00208825

/

Pattern: metacluster_0/pattern_24

Significance: 0.0233345

Absent
wES;5th_Rhmbmr;E8.5;A;GEO

Pattern: metacluster_0/pattern_12

Significance: 0.0281122

/

Pattern: metacluster_0/pattern_22

Significance: 0.03938130000000001

Absent
npES;5th_Rhmbmr_delA;E8.5;A;GEO

Pattern: metacluster_0/pattern_5

Significance: 0.042304900000000006

Absent
wES;posterior;1;E9.5;A;GEO

Pattern: metacluster_1/pattern_5

Significance: 0.0192295

Absent
wES;posterior;2;E9.5;A;GEO

Pattern: metacluster_0/pattern_9

Significance: 0.010449

Absent
wES;posterior;1;E8.5;A;GEO

Pattern: metacluster_0/pattern_10

Significance: 0.0259443

Absent
npES;posterior_delA;E8.5;A;GEO

Pattern: metacluster_0/pattern_8

Significance: 0.0069666

Absent
npES;posterior_delC;E8.5;A;GEO

Pattern: metacluster_0/pattern_9

Significance: 0.0369575

Absent
wES.CRNL_NRL_CRST;E10.5;A;GEO

Pattern: metacluster_0/pattern_5

Significance: 0.0541784

Absent
iVIP_NRN;A;GEO

Pattern: metacluster_1/pattern_0

Significance: 0.043401

Absent
ISP;A;CL

Pattern: metacluster_1/pattern_4

Significance: 0.015440899999999999

Absent
Corticotrope;A;GEO

Pattern: metacluster_0/pattern_17

Significance: 0.00562627

Absent
LNG;A;CL

Pattern: metacluster_1/pattern_20

Significance: 0.00479334

Absent
Melanotrope;A;GEO

Pattern: metacluster_0/pattern_8

Significance: 0.0137314

Absent
Heart;D;En

Pattern: metacluster_0/pattern_8

Significance: 0.0376882

Absent
BRN;OLFTRY_BLB;A;CL

Pattern: metacluster_0/pattern_13

Significance: 0.00475906

Absent
LNG;8wks;D;GEO

Pattern: metacluster_0/pattern_21

Significance: 0.039289300000000006

Absent
NIH3T3_FBROBLST;D;En

Pattern: metacluster_1/pattern_8

Significance: 0.0477471

Absent
wCH12_drug;A;CL

Pattern: metacluster_1/pattern_17

Significance: 0.028972700000000004

Absent
KDNY;P0;D;En

Pattern: metacluster_1/pattern_9

Significance: 0.048015300000000004

Absent
LNG;8wks;D;En

Pattern: metacluster_0/pattern_17

Significance: 0.0206591

Absent
RTN;A;GEO

Pattern: metacluster_0/pattern_6

Significance: 0.00483377

Absent
CRBLM;D;En

Pattern: metacluster_1/pattern_1

Significance: 0.0023749

Absent
wES;Hnd_BRN;E11.5;D;En

Pattern: metacluster_0/pattern_4

Significance: 0.049417800000000005

Absent
wES;Hnd_BRN;E14.5;D;En

Pattern: metacluster_0/pattern_7

Significance: 0.00757783

/

Pattern: metacluster_0/pattern_12

Significance: 0.00959725

Absent
wES;Md_BRN;E14.4;D;En

Pattern: metacluster_0/pattern_4

Significance: 0.00548342

Absent
Unique Cell types only Homer finds Atoh1: #2

Cell typeModiscoHomer
wES;LNG;E14.5;D;EnAbsent

Pattern: motif13.motif

Significance: 0.0143565

DP3a;A;CLAbsent

Pattern: motif12.motif

Significance: 0.031463200000000004