In [1]:
# Parameters
data_name = "Tcf4"
task_idxs = "0-213,216-278"
homer_root = "/srv/scratch/msharmin/mouse_hem/with_tfd/full_mouse50/Naive_scans"
modisco_root = "/srv/scratch/msharmin/mouse_hem/with_tfd/full_mouse50/Naive_modisco2019"
overwrite = False
In [2]:
from matlas.reports import collect_motifDB_to_be_displayed, display_comparative_cell_types

load data from labcluster

Using TensorFlow backend.
2019-08-23 11:42:38,570 [WARNING] git-lfs not installed
In [3]:
homer_matches, modisco_matches = collect_motifDB_to_be_displayed(task_idxs, homer_root, modisco_root, 
                                                              overwrite=False)

TF-MoDISco is using the TensorFlow backend.
In [4]:
display_comparative_cell_types(data_name, homer_matches, modisco_matches)
Tcf4: Motif: M08775_2.00



Forward PWM

Reverse PWM

Shared Cell types both TF-MoDISco and Homer finds Tcf4: #20

Cell typeModiscoHomer
wES;limb;E14.5;D;En

Pattern: metacluster_1/pattern_1

Significance: 0.0595285

Pattern: motif5.motif

Significance: 0.00866069

wES;limb;E11.5;D;En

Pattern: metacluster_0/pattern_6

Significance: 0.052622300000000004

Pattern: motif12.motif

Significance: 0.029273200000000003

wES;Fr_lmb;E11.5;D;En

Pattern: metacluster_1/pattern_3

Significance: 0.0171961

Pattern: motif6.motif

Significance: 0.0280082

largeDPprecrsr;CD4+CD8+CD69-;A;CL

Pattern: metacluster_1/pattern_5

Significance: 0.00104629

Pattern: motif18.motif

Significance: 0.027719099999999997

wES;FaceP;E14.5;D;En

Pattern: metacluster_0/pattern_1

Significance: 0.055013900000000004

Pattern: motif5.motif

Significance: 0.010923299999999999

wES;FaceP;E11.5;D;En

Pattern: metacluster_1/pattern_2

Significance: 0.0588384

Pattern: motif7.motif

Significance: 0.0298514

smallDPprecrsor;CD4+CD8+CD69-;A;CL

Pattern: metacluster_1/pattern_4

Significance: 0.00173917

Pattern: motif13.motif

Significance: 0.026623599999999997

SKLTL_Muscle;8wks;D;En

Pattern: metacluster_1/pattern_12

Significance: 0.03340119999999999

Pattern: motif10.motif

Significance: 0.0350165

prePLSM_B;A;GEO

Pattern: metacluster_1/pattern_20

Significance: 0.0596758

Pattern: motif22.motif

Significance: 0.048148500000000004

NPC;F129;A;GEO

Pattern: metacluster_1/pattern_5

Significance: 0.0362909

/

Pattern: metacluster_1/pattern_23

Significance: 0.0558234

Pattern: motif10.motif

Significance: 0.05376469999999999

plasmaB;A;CL

Pattern: metacluster_1/pattern_5

Significance: 0.000386173

Pattern: motif9.motif

Significance: 0.0211859

preB_BMD;A;GEO

Pattern: metacluster_1/pattern_5

Significance: 0.0013341

Pattern: motif9.motif

Significance: 0.0329378

NPC;G4;A;GEO

Pattern: metacluster_1/pattern_5

Significance: 0.0107399

Pattern: motif9.motif

Significance: 0.024250599999999997

NPC;mE6;A;GEO

Pattern: metacluster_1/pattern_7

Significance: 0.010267499999999999

Pattern: motif11.motif

Significance: 0.05519450000000001

DP;A;CL

Pattern: metacluster_1/pattern_10

Significance: 0.00101402

Pattern: motif17.motif

Significance: 0.0328666

DP3b;A;CL

Pattern: metacluster_1/pattern_3

Significance: 0.00342266

Pattern: motif7.motif

Significance: 0.0585529

ISP;A;CL

Pattern: metacluster_1/pattern_4

Significance: 0.0070572000000000005

Pattern: motif14.motif

Significance: 0.019340200000000002

CRBL_GRNL_Precrsr;A;GEO

Pattern: metacluster_0/pattern_0

Significance: 0.058225599999999995

Pattern: motif2.motif

Significance: 0.0423809

wES;MSDRM;E11.5;D;En

Pattern: metacluster_0/pattern_1

Significance: 0.0238908

Pattern: motif4.motif

Significance: 0.0586575

Heart;D;En

Pattern: metacluster_0/pattern_8

Significance: 0.050513800000000005

Pattern: motif13.motif

Significance: 0.040031

Unique Cell types only TF-MoDISco finds Tcf4: #37

Cell typeModiscoHomer
proB;A;CL

Pattern: metacluster_1/pattern_3

Significance: 0.00207037

Absent
preB;A;CL

Pattern: metacluster_1/pattern_4

Significance: 0.0030674

Absent
wES;NRL_Tube;E11.5;D;En

Pattern: metacluster_1/pattern_5

Significance: 0.00829602

Absent
B1_B;A;CL

Pattern: metacluster_1/pattern_19

Significance: 0.0345565

Absent
B;B220_CD43;A;GEO

Pattern: metacluster_1/pattern_9

Significance: 0.00143812

Absent
wES;3rd_Rhmbmr;E8.5;A;GEO

Pattern: metacluster_0/pattern_10

Significance: 0.0168477

Absent
npES;3rd_Rhmbmr_delC;E8.5;A;GEO

Pattern: metacluster_0/pattern_24

Significance: 0.0232627

Absent
wES;5th_Rhmbmr;E9.5;A;GEO

Pattern: metacluster_0/pattern_15

Significance: 0.0130227

Absent
wES;5th_Rhmbmr;E8.5;A;GEO

Pattern: metacluster_0/pattern_12

Significance: 0.020958

/

Pattern: metacluster_0/pattern_22

Significance: 0.0369166

Absent
wES;posterior;1;E9.5;A;GEO

Pattern: metacluster_1/pattern_5

Significance: 0.0450088

Absent
wES;posterior;2;E9.5;A;GEO

Pattern: metacluster_0/pattern_9

Significance: 0.0191048

/

Pattern: metacluster_0/pattern_25

Significance: 0.048389800000000004

Absent
wES;posterior;1;E8.5;A;GEO

Pattern: metacluster_0/pattern_10

Significance: 0.0260655

Absent
npES;posterior_delA;E8.5;A;GEO

Pattern: metacluster_0/pattern_8

Significance: 0.0236675

Absent
npES;posterior_delC;E8.5;A;GEO

Pattern: metacluster_0/pattern_9

Significance: 0.030219599999999996

Absent
wES.CRNL_NRL_CRST;E10.5;A;GEO

Pattern: metacluster_0/pattern_5

Significance: 0.05230599999999999

Absent
NPC;Ch13;A;GEO

Pattern: metacluster_1/pattern_9

Significance: 0.0296252

/

Pattern: metacluster_1/pattern_17

Significance: 0.0260098

Absent
iPV_NRN;A;GEO

Pattern: metacluster_1/pattern_3

Significance: 0.03686969999999999

Absent
iVIP_NRN;A;GEO

Pattern: metacluster_1/pattern_0

Significance: 0.05146799999999999

Absent
Corticotrope;A;GEO

Pattern: metacluster_0/pattern_17

Significance: 0.04170530000000001

Absent
LNG;A;CL

Pattern: metacluster_1/pattern_20

Significance: 0.026104900000000004

Absent
Melanotrope;A;GEO

Pattern: metacluster_0/pattern_8

Significance: 0.014206299999999998

Absent
BRN;OLFTRY_BLB;A;CL

Pattern: metacluster_0/pattern_13

Significance: 0.00899823

Absent
WHL_BRN;8wks;D;GEO

Pattern: metacluster_1/pattern_10

Significance: 0.023891299999999997

Absent
wCH12_drug;A;CL

Pattern: metacluster_1/pattern_17

Significance: 0.00882521

Absent
KDNY;P0;D;En

Pattern: metacluster_1/pattern_9

Significance: 0.0542102

Absent
LNG;8wks;D;En

Pattern: metacluster_0/pattern_17

Significance: 0.052623300000000005

Absent
Heart;8wks;D;En

Pattern: metacluster_0/pattern_11

Significance: 0.021912099999999997

Absent
RTN;D1;D;En

Pattern: metacluster_0/pattern_4

Significance: 0.0265156

Absent
wES;RTN;E11.5;D;En

Pattern: metacluster_0/pattern_3

Significance: 0.0365281

Absent
Fr_BRN;P0;D;En

Pattern: metacluster_1/pattern_15

Significance: 0.0214356

Absent
Hnd_BRN;P0;D;En

Pattern: metacluster_1/pattern_3

Significance: 0.0504011

Absent
wES;Hnd_BRN;E11.5;D;En

Pattern: metacluster_0/pattern_4

Significance: 0.020774900000000002

Absent
wES;Hnd_BRN;E14.5;D;En

Pattern: metacluster_0/pattern_7

Significance: 0.037435699999999995

Absent
wES;Md_BRN;E14.4;D;En

Pattern: metacluster_0/pattern_4

Significance: 0.0249197

Absent
wES;Md_BRN;E11.5;D;En

Pattern: metacluster_0/pattern_4

Significance: 0.0401004

Absent
wES;WHL_BRN;E14.5;D;En

Pattern: metacluster_1/pattern_5

Significance: 0.0375987

Absent
WHL_BRN;8wks;D;En

Pattern: metacluster_1/pattern_11

Significance: 0.037914300000000005

Absent
Unique Cell types only Homer finds Tcf4: #6

Cell typeModiscoHomer
wES;Hnd_lmb;E11.5;D;EnAbsent

Pattern: motif11.motif

Significance: 0.048824900000000004

LNG;P0;D;EnAbsent

Pattern: motif18.motif

Significance: 0.030110599999999998

wES;LNG;E14.5;D;EnAbsent

Pattern: motif13.motif

Significance: 0.0248011

A20;B-lymphoma;D;EnAbsent

Pattern: motif13.motif

Significance: 0.059223300000000006

DP3a;A;CLAbsent

Pattern: motif12.motif

Significance: 0.025635900000000003

3T3-L1;D;EnAbsent

Pattern: motif15.motif

Significance: 0.056063699999999994