In [1]:
# Parameters
data_name = "Nr5a2"
task_idxs = "0-213,216-278"
homer_root = "/srv/scratch/msharmin/mouse_hem/with_tfd/full_mouse50/Naive_scans"
modisco_root = "/srv/scratch/msharmin/mouse_hem/with_tfd/full_mouse50/Naive_modisco2019"
overwrite = False
In [2]:
from matlas.reports import collect_motifDB_to_be_displayed, display_comparative_cell_types

load data from labcluster

Using TensorFlow backend.
2019-08-23 11:26:13,862 [WARNING] git-lfs not installed
In [3]:
homer_matches, modisco_matches = collect_motifDB_to_be_displayed(task_idxs, homer_root, modisco_root, 
                                                              overwrite=False)

TF-MoDISco is using the TensorFlow backend.
In [4]:
display_comparative_cell_types(data_name, homer_matches, modisco_matches)
Nr5a2: Motif: M08158_2.00



Forward PWM

Reverse PWM

Shared Cell types both TF-MoDISco and Homer finds Nr5a2: #20

Cell typeModiscoHomer
wES;5th_Rhmbmr;E8.5;A;GEO

Pattern: metacluster_0/pattern_5

Significance: 0.0283994

Pattern: motif17.motif

Significance: 0.0537982

npES;5th_Rhmbmr_delA;E8.5;A;GEO

Pattern: metacluster_0/pattern_17

Significance: 0.0414579

Pattern: motif18.motif

Significance: 0.0520577

LVR;8wks;D;En

Pattern: metacluster_0/pattern_0

Significance: 0.033660300000000004

Pattern: motif2.motif

Significance: 0.0587388

npES;ZHBTC4;Brg1fl_fl;untreat;A;GEO

Pattern: metacluster_1/pattern_23

Significance: 0.00200655

Pattern: motif32.motif

Significance: 0.00221071

ES;ZhBTc4;1;D;GEO

Pattern: metacluster_1/pattern_11

Significance: 0.00016041799999999998

Pattern: motif14.motif

Significance: 0.05855369999999999

ES;ZhBTc4;2;D;GEO

Pattern: metacluster_1/pattern_12

Significance: 0.0008257830000000001

Pattern: motif12.motif

Significance: 0.00874741

ES;D0;D;GEO

Pattern: metacluster_0/pattern_10

Significance: 0.000135945

Pattern: motif14.motif

Significance: 0.00196337

Adipocyte_3T3-L1D;C57BL6;D8;D;En

Pattern: metacluster_1/pattern_9

Significance: 0.055358500000000005

Pattern: motif10.motif

Significance: 0.03994330000000001

LVR;8wks;D;GEO

Pattern: metacluster_1/pattern_0

Significance: 0.0407739

/

Pattern: metacluster_1/pattern_17

Significance: 0.00139546

Pattern: motif1.motif

Significance: 0.0520078

/

Pattern: motif5.motif

Significance: 0.0444551

LRG_INTSTN;8wks;D;En

Pattern: metacluster_1/pattern_2

Significance: 0.0432236

Pattern: motif3.motif

Significance: 0.0232902

Adrenal;A;CL

Pattern: metacluster_1/pattern_0

Significance: 0.000180489

/

Pattern: metacluster_1/pattern_15

Significance: 0.000379226

Pattern: motif2.motif

Significance: 0.0009040119999999999

wES;MSDRM;E11.5;D;En

Pattern: metacluster_0/pattern_11

Significance: 0.036392400000000005

Pattern: motif19.motif

Significance: 0.05950219999999999

ES;ZhBTc4;untreated;A;GEO

Pattern: metacluster_1/pattern_10

Significance: 0.011352600000000001

Pattern: motif19.motif

Significance: 0.00188247

npES;ZHBTC4;doxyc;treat;A;GEO

Pattern: metacluster_0/pattern_13

Significance: 0.000566501

Pattern: motif14.motif

Significance: 0.00917006

ES;E14;D;En

Pattern: metacluster_1/pattern_15

Significance: 0.00119229

/

Pattern: metacluster_1/pattern_19

Significance: 0.0417673

Pattern: motif23.motif

Significance: 0.0585054

ES;C57BL_6J;R1;D;En

Pattern: metacluster_1/pattern_13

Significance: 0.00157595

Pattern: motif22.motif

Significance: 0.031004000000000004

npES;3rd_Rhmbmr_delA;E8.5;A;GEO

Pattern: metacluster_0/pattern_15

Significance: 0.0366153

/

Pattern: metacluster_0/pattern_17

Significance: 0.05270419999999999

Pattern: motif20.motif

Significance: 0.0582139

ES;129S1_SVImJ_CJ7;D;En

Pattern: metacluster_1/pattern_9

Significance: 0.0007413010000000001

Pattern: motif18.motif

Significance: 0.00369652

placenta;A;CL

Pattern: metacluster_0/pattern_11

Significance: 0.055096400000000004

Pattern: motif12.motif

Significance: 0.05183340000000001

KDNY;8wks;D;En

Pattern: metacluster_1/pattern_1

Significance: 0.0594962

Pattern: motif2.motif

Significance: 0.0514163

Unique Cell types only TF-MoDISco finds Nr5a2: #31

Cell typeModiscoHomer
T_MLD;TCR_SV40-I_CD8+;D28;A;GEO

Pattern: metacluster_1/pattern_17

Significance: 0.0548582

Absent
wES;Hnd_lmb;E11.5;D;En

Pattern: metacluster_0/pattern_22

Significance: 0.0494844

/

Pattern: metacluster_0/pattern_23

Significance: 0.0383703

Absent
memT_tmrD_lstr;TCR_SV40-I_CD8+;D14;A;GEO

Pattern: metacluster_0/pattern_17

Significance: 0.017946200000000002

Absent
memT_tmrD;TCR_SV40-I_CD8+;D14;A;GEO

Pattern: metacluster_1/pattern_16

Significance: 0.046637

Absent
416B;HMTP_SPNSN;CD34+;D;En

Pattern: metacluster_1/pattern_18

Significance: 0.000184832

Absent
wES;3rd_Rhmbmr;E8.5;A;GEO

Pattern: metacluster_0/pattern_17

Significance: 0.038312900000000004

Absent
Tfr_mut;CD4+CD44+CXCR5+PD1+CD25+;A;CL

Pattern: metacluster_1/pattern_17

Significance: 0.038095300000000006

Absent
npES;3rd_Rhmbmr_delC;E8.5;A;GEO

Pattern: metacluster_0/pattern_16

Significance: 0.043111500000000004

Absent
wES;posterior;1;E9.5;A;GEO

Pattern: metacluster_1/pattern_12

Significance: 0.0176727

Absent
wES;posterior;2;E9.5;A;GEO

Pattern: metacluster_0/pattern_8

Significance: 0.0572819

/

Pattern: metacluster_0/pattern_15

Significance: 0.0531196

Absent
wES;posterior;1;E8.5;A;GEO

Pattern: metacluster_0/pattern_21

Significance: 0.049201800000000004

/

Pattern: metacluster_0/pattern_24

Significance: 0.0527789

Absent
npES;posterior_delC;E8.5;A;GEO

Pattern: metacluster_0/pattern_20

Significance: 0.0328065

/

Pattern: metacluster_0/pattern_21

Significance: 0.0467303

Absent
CD4+CD8-TCR+CD25-Foxp3+;A;CL

Pattern: metacluster_1/pattern_23

Significance: 0.0268551

Absent
CD4+CD8-TCR+CD25+Foxp3+;A;CL

Pattern: metacluster_1/pattern_14

Significance: 0.04833540000000001

Absent
iPV_NRN;A;GEO

Pattern: metacluster_1/pattern_8

Significance: 0.03764869999999999

Absent
ES;E14;A;CL

Pattern: metacluster_1/pattern_16

Significance: 0.037056

Absent
SML_INTSTN;A;CL

Pattern: metacluster_0/pattern_3

Significance: 0.0477116

Absent
LRG_INTSTN;A;CL

Pattern: metacluster_0/pattern_1

Significance: 0.0298936

Absent
Melanotrope;A;GEO

Pattern: metacluster_0/pattern_13

Significance: 0.0493394

Absent
Muscle;A;CL

Pattern: metacluster_1/pattern_21

Significance: 0.0498601

Absent
416B_MP;CD34+;D;GEO

Pattern: metacluster_1/pattern_19

Significance: 0.000206446

Absent
KDNY;P0;D;En

Pattern: metacluster_1/pattern_23

Significance: 0.0446582

Absent
wES;LVR;E11.5;D.;En

Pattern: metacluster_1/pattern_15

Significance: 0.0320219

Absent
ES;J1;A;CL

Pattern: metacluster_1/pattern_12

Significance: 0.00193194

Absent
LVR;P0;D;En

Pattern: metacluster_1/pattern_10

Significance: 0.0503598

Absent
ES;129SV_Jae_C57BL6J;A;GEO

Pattern: metacluster_1/pattern_15

Significance: 0.0111925

Absent
Heart;8wks;D;En

Pattern: metacluster_0/pattern_16

Significance: 0.015126599999999999

Absent
Heart;P0;D;En

Pattern: metacluster_1/pattern_19

Significance: 0.00513681

Absent
ILC2+IL33+IL25;A;GEO

Pattern: metacluster_1/pattern_13

Significance: 0.051454

Absent
416B_MP;CD34+;D;En

Pattern: metacluster_1/pattern_20

Significance: 0.000253812

Absent
T_LCMV;CD8+;D35;A;GEO

Pattern: metacluster_1/pattern_16

Significance: 0.0553677

Absent
No Cell types only Homer finds Nr5a2