In [1]:
# Parameters
data_name = "Nr2f6"
task_idxs = "0-213,216-278"
homer_root = "/srv/scratch/msharmin/mouse_hem/with_tfd/full_mouse50/Naive_scans"
modisco_root = "/srv/scratch/msharmin/mouse_hem/with_tfd/full_mouse50/Naive_modisco2019"
overwrite = False
In [2]:
from matlas.reports import collect_motifDB_to_be_displayed, display_comparative_cell_types

load data from labcluster

Using TensorFlow backend.
2019-08-23 11:25:42,647 [WARNING] git-lfs not installed
In [3]:
homer_matches, modisco_matches = collect_motifDB_to_be_displayed(task_idxs, homer_root, modisco_root, 
                                                              overwrite=False)

TF-MoDISco is using the TensorFlow backend.
In [4]:
display_comparative_cell_types(data_name, homer_matches, modisco_matches)
Nr2f6: Motif: M00811_2.00



Forward PWM

Reverse PWM

Shared Cell types both TF-MoDISco and Homer finds Nr2f6: #18

Cell typeModiscoHomer
wES;5th_Rhmbmr;E8.5;A;GEO

Pattern: metacluster_0/pattern_5

Significance: 0.0066077

Pattern: motif17.motif

Significance: 0.0230551

npES;5th_Rhmbmr_delA;E8.5;A;GEO

Pattern: metacluster_0/pattern_14

Significance: 0.045429199999999996

/

Pattern: metacluster_0/pattern_17

Significance: 0.056746300000000006

Pattern: motif18.motif

Significance: 0.0472517

wES;posterior;1;E9.5;A;GEO

Pattern: metacluster_1/pattern_12

Significance: 0.0063415

Pattern: motif8.motif

Significance: 0.0582553

wES;posterior;2;E9.5;A;GEO

Pattern: metacluster_0/pattern_8

Significance: 0.0027523000000000005

/

Pattern: metacluster_0/pattern_15

Significance: 0.0531196

Pattern: motif9.motif

Significance: 0.0366152

LVR;8wks;D;En

Pattern: metacluster_0/pattern_0

Significance: 0.017383000000000003

Pattern: motif2.motif

Significance: 0.010003100000000001

wES;5th_Rhmbmr;E9.5;A;GEO

Pattern: metacluster_0/pattern_10

Significance: 0.0129572

Pattern: motif9.motif

Significance: 0.043267599999999996

ES;ZhBTc4;1;D;GEO

Pattern: metacluster_1/pattern_11

Significance: 0.00756166

Pattern: motif14.motif

Significance: 0.0254546

LRG_INTSTN;8wks;D;En

Pattern: metacluster_1/pattern_2

Significance: 0.0363508

Pattern: motif3.motif

Significance: 0.027571

Adipocyte_3T3-L1D;C57BL6;D8;D;En

Pattern: metacluster_1/pattern_9

Significance: 0.0440797

Pattern: motif10.motif

Significance: 0.0312688

LVR;8wks;D;GEO

Pattern: metacluster_1/pattern_0

Significance: 0.021425299999999998

/

Pattern: metacluster_1/pattern_17

Significance: 0.0283709

Pattern: motif1.motif

Significance: 0.022453400000000002

wES;MSDRM;E11.5;D;En

Pattern: metacluster_0/pattern_11

Significance: 0.046885

Pattern: motif19.motif

Significance: 0.05950219999999999

SML_INTSTN;A;CL

Pattern: metacluster_0/pattern_3

Significance: 0.0564344

Pattern: motif5.motif

Significance: 0.00719121

LRG_INTSTN;A;CL

Pattern: metacluster_0/pattern_1

Significance: 5.65837e-05

Pattern: motif2.motif

Significance: 0.0060986999999999994

placenta;A;CL

Pattern: metacluster_0/pattern_11

Significance: 0.0438811

Pattern: motif12.motif

Significance: 8.981010000000001e-08

npES;ZHBTC4;Brg1fl_fl;untreat;A;GEO

Pattern: metacluster_1/pattern_23

Significance: 0.0501153

Pattern: motif32.motif

Significance: 0.0510919

npES;3rd_Rhmbmr_delA;E8.5;A;GEO

Pattern: metacluster_0/pattern_15

Significance: 0.0194509

/

Pattern: metacluster_0/pattern_17

Significance: 0.054755899999999996

Pattern: motif20.motif

Significance: 3.0958e-07

npES;3rd_Rhmbmr_delC;E8.5;A;GEO

Pattern: metacluster_0/pattern_13

Significance: 0.0542436

/

Pattern: metacluster_0/pattern_16

Significance: 0.043111500000000004

Pattern: motif15.motif

Significance: 0.03524

KDNY;8wks;D;En

Pattern: metacluster_1/pattern_1

Significance: 0.00518681

Pattern: motif2.motif

Significance: 0.024997

Unique Cell types only TF-MoDISco finds Nr2f6: #41

Cell typeModiscoHomer
T_MLD;TCR_SV40-I_CD8+;D28;A;GEO

Pattern: metacluster_1/pattern_17

Significance: 0.00535031

Absent
wES;limb;E11.5;D;En

Pattern: metacluster_0/pattern_16

Significance: 0.015604900000000001

Absent
wES;Hnd_lmb;E11.5;D;En

Pattern: metacluster_0/pattern_15

Significance: 0.0161815

/

Pattern: metacluster_0/pattern_22

Significance: 0.00429113

/

Pattern: metacluster_0/pattern_23

Significance: 0.048980699999999995

Absent
memT_tmrD_lstr;TCR_SV40-I_CD8+;D14;A;GEO

Pattern: metacluster_0/pattern_17

Significance: 0.017946200000000002

Absent
memT_tmrD;TCR_SV40-I_CD8+;D14;A;GEO

Pattern: metacluster_1/pattern_16

Significance: 0.058513800000000005

Absent
STMCH;P0;D;En

Pattern: metacluster_1/pattern_11

Significance: 0.023400099999999997

Absent
416B;HMTP_SPNSN;CD34+;D;En

Pattern: metacluster_1/pattern_18

Significance: 0.0258322

Absent
BL_CN_PHT_RCPTR;A;GEO

Pattern: metacluster_1/pattern_18

Significance: 0.059325800000000005

Absent
CN_PHT_RCPTR;A;GEO

Pattern: metacluster_1/pattern_10

Significance: 0.056640699999999995

Absent
wES;3rd_Rhmbmr;E8.5;A;GEO

Pattern: metacluster_0/pattern_14

Significance: 0.053231600000000004

/

Pattern: metacluster_0/pattern_17

Significance: 0.0491816

Absent
Tfr_mut;CD4+CD44+CXCR5+PD1+CD25+;A;CL

Pattern: metacluster_1/pattern_17

Significance: 0.0217628

Absent
npES;5th_Rhmbmr_delC;E8.5;A;GEO

Pattern: metacluster_1/pattern_8

Significance: 0.029656799999999997

Absent
largeDPprecrsr;CD4+CD8+CD69-;A;CL

Pattern: metacluster_1/pattern_17

Significance: 0.0256502

Absent
smallDPprecrsor;CD4+CD8+CD69-;A;CL

Pattern: metacluster_1/pattern_15

Significance: 0.041874800000000004

Absent
CD4+CD8intTCR+CD69+CD24+;B2defM;A;CL

Pattern: metacluster_1/pattern_14

Significance: 0.0269621

Absent
wES;posterior;1;E8.5;A;GEO

Pattern: metacluster_0/pattern_21

Significance: 0.00407756

/

Pattern: metacluster_0/pattern_24

Significance: 0.0376525

Absent
npES;posterior_delA;E8.5;A;GEO

Pattern: metacluster_0/pattern_13

Significance: 0.014282399999999999

Absent
npES;posterior_delC;E8.5;A;GEO

Pattern: metacluster_0/pattern_20

Significance: 0.04088119999999999

/

Pattern: metacluster_0/pattern_21

Significance: 0.007474

/

Pattern: metacluster_0/pattern_22

Significance: 0.00931672

Absent
BCK_SKN;A;GEO

Pattern: metacluster_0/pattern_22

Significance: 0.0208166

Absent
CD4+CD8-TCR+CD25-Foxp3+;A;CL

Pattern: metacluster_1/pattern_23

Significance: 0.0268551

Absent
CD4+CD8-TCR+CD25+Foxp3+;A;CL

Pattern: metacluster_1/pattern_14

Significance: 0.058740999999999995

Absent
wES.CRNL_NRL_CRST;E10.5;A;GEO

Pattern: metacluster_0/pattern_18

Significance: 0.0549306

Absent
ES;E14;A;CL

Pattern: metacluster_1/pattern_10

Significance: 0.0392403

Absent
ThMS_MEC;Aire++;A;GEO

Pattern: metacluster_1/pattern_16

Significance: 0.00975293

Absent
Melanotrope;A;GEO

Pattern: metacluster_0/pattern_13

Significance: 0.05986469999999999

Absent
Muscle;A;CL

Pattern: metacluster_1/pattern_21

Significance: 0.00505748

Absent
Adrenal;A;CL

Pattern: metacluster_1/pattern_15

Significance: 0.054765499999999995

Absent
ES;D0;D;GEO

Pattern: metacluster_0/pattern_10

Significance: 0.0123557

Absent
416B_MP;CD34+;D;GEO

Pattern: metacluster_1/pattern_19

Significance: 0.00748905

Absent
ES;E14;D;En

Pattern: metacluster_1/pattern_15

Significance: 0.017243

Absent
ES;C57BL_6J;R1;D;En

Pattern: metacluster_1/pattern_13

Significance: 0.025706299999999998

Absent
KDNY;P0;D;En

Pattern: metacluster_1/pattern_23

Significance: 0.0214039

Absent
wES;LVR;E11.5;D.;En

Pattern: metacluster_1/pattern_15

Significance: 3.7709000000000005e-07

Absent
ES;J1;A;CL

Pattern: metacluster_1/pattern_12

Significance: 0.0355361

Absent
LVR;P0;D;En

Pattern: metacluster_1/pattern_10

Significance: 0.013108600000000002

Absent
ES;129SV_Jae_C57BL6J;A;GEO

Pattern: metacluster_1/pattern_15

Significance: 0.0276707

Absent
Heart;8wks;D;En

Pattern: metacluster_0/pattern_16

Significance: 0.039612699999999994

Absent
ILC2+IL33+IL25;A;GEO

Pattern: metacluster_1/pattern_13

Significance: 0.057447000000000005

Absent
416B_MP;CD34+;D;En

Pattern: metacluster_1/pattern_20

Significance: 0.039663199999999996

Absent
T_LCMV;CD8+;D35;A;GEO

Pattern: metacluster_1/pattern_16

Significance: 0.00513376

Absent
T_MLD;TCR_SV40-I_CD8+;D7;A;GEO

Pattern: metacluster_1/pattern_10

Significance: 0.054307100000000004

Absent
Unique Cell types only Homer finds Nr2f6: #2

Cell typeModiscoHomer
DC_BMD;A;CLAbsent

Pattern: motif13.motif

Significance: 0.026657099999999996

ES;ZhBTc4;untreated;A;GEOAbsent

Pattern: motif19.motif

Significance: 0.053002