In [1]:
# Parameters
data_name = "Neurod2"
task_idxs = "0-213,216-278"
homer_root = "/srv/scratch/msharmin/mouse_hem/with_tfd/full_mouse50/Naive_scans"
modisco_root = "/srv/scratch/msharmin/mouse_hem/with_tfd/full_mouse50/Naive_modisco2019"
overwrite = False
In [2]:
from matlas.reports import collect_motifDB_to_be_displayed, display_comparative_cell_types

load data from labcluster

Using TensorFlow backend.
2019-08-23 11:22:00,218 [WARNING] git-lfs not installed
In [3]:
homer_matches, modisco_matches = collect_motifDB_to_be_displayed(task_idxs, homer_root, modisco_root, 
                                                              overwrite=False)

TF-MoDISco is using the TensorFlow backend.
In [4]:
display_comparative_cell_types(data_name, homer_matches, modisco_matches)
Neurod2: Motif: M08770_2.00



Forward PWM

Reverse PWM

Shared Cell types both TF-MoDISco and Homer finds Neurod2: #30

Cell typeModiscoHomer
wES;limb;E14.5;D;En

Pattern: metacluster_1/pattern_1

Significance: 0.05664119999999999

Pattern: motif5.motif

Significance: 0.00020696

wES;limb;E11.5;D;En

Pattern: metacluster_0/pattern_6

Significance: 0.00770948

Pattern: motif12.motif

Significance: 0.055476599999999994

wES;FaceP;E14.5;D;En

Pattern: metacluster_0/pattern_1

Significance: 0.0410005

Pattern: motif5.motif

Significance: 0.00149561

wES;NRL_Tube;E11.5;D;En

Pattern: metacluster_1/pattern_5

Significance: 2.6924200000000002e-05

Pattern: motif15.motif

Significance: 0.0293269

SKLTL_Muscle;8wks;D;En

Pattern: metacluster_1/pattern_12

Significance: 0.0163444

Pattern: motif10.motif

Significance: 0.023071

preB_BMD;A;GEO

Pattern: metacluster_1/pattern_5

Significance: 0.0147785

Pattern: motif9.motif

Significance: 0.017527

B;B220_CD43;A;GEO

Pattern: metacluster_1/pattern_9

Significance: 0.0270797

Pattern: motif11.motif

Significance: 0.0037476999999999996

MTR_NRN_MN1;methyl3;D;En

Pattern: metacluster_0/pattern_12

Significance: 0.00208927

Pattern: motif10.motif

Significance: 0.0353035

NPC;F129;A;GEO

Pattern: metacluster_1/pattern_5

Significance: 0.00641608

Pattern: motif10.motif

Significance: 0.0362397

NPC;G4;A;GEO

Pattern: metacluster_1/pattern_5

Significance: 0.0112142

Pattern: motif9.motif

Significance: 0.00922498

NPC;mE6;A;GEO

Pattern: metacluster_1/pattern_7

Significance: 0.0178967

Pattern: motif11.motif

Significance: 0.018741099999999997

ePyramidal_NRN;A;GEO

Pattern: metacluster_1/pattern_2

Significance: 1.2460999999999998e-07

Pattern: motif4.motif

Significance: 0.00921175

eCortical_NRN;A;GEO

Pattern: metacluster_1/pattern_3

Significance: 1.3937e-05

Pattern: motif4.motif

Significance: 1.8416400000000002e-05

BRN;FRNTL_CRTX;A;CL

Pattern: metacluster_1/pattern_12

Significance: 4.988e-06

Pattern: motif15.motif

Significance: 0.000582149

BRN;SNSR_MTR_CRTX;A;CL

Pattern: metacluster_1/pattern_6

Significance: 2.68822e-06

Pattern: motif7.motif

Significance: 9.18442e-07

BRN;CRBLM;A;CL

Pattern: metacluster_0/pattern_7

Significance: 2.74288e-05

Pattern: motif7.motif

Significance: 0.00388088

WHL_BRN;8wks;D;GEO

Pattern: metacluster_1/pattern_2

Significance: 3.18527e-06

/

Pattern: metacluster_1/pattern_10

Significance: 0.00166683

Pattern: motif2.motif

Significance: 0.005037

wES;WHL_BRN;E14.5;D;GEO

Pattern: metacluster_0/pattern_2

Significance: 2.9969100000000003e-07

Pattern: motif13.motif

Significance: 0.00177863

CRBL_GRNL_Precrsr;A;GEO

Pattern: metacluster_0/pattern_0

Significance: 2.69745e-07

Pattern: motif2.motif

Significance: 6.804860000000001e-06

RTN;D1;D;En

Pattern: metacluster_0/pattern_4

Significance: 2.6086099999999997e-06

Pattern: motif16.motif

Significance: 0.00895866

wES;RTN;E11.5;D;En

Pattern: metacluster_0/pattern_3

Significance: 3.4697199999999997e-06

Pattern: motif14.motif

Significance: 0.00460232

CRBLM;D;En

Pattern: metacluster_1/pattern_1

Significance: 1.72855e-06

Pattern: motif2.motif

Significance: 0.00871669

wES;MSDRM;E11.5;D;En

Pattern: metacluster_0/pattern_1

Significance: 0.000121628

Pattern: motif4.motif

Significance: 0.00242625

wES.Fr_BRN;E14.4;D;En

Pattern: metacluster_0/pattern_4

Significance: 6.45075e-11

Pattern: motif11.motif

Significance: 5.744359999999999e-08

Fr_BRN;P0;D;En

Pattern: metacluster_1/pattern_4

Significance: 0.00010771399999999999

/

Pattern: metacluster_1/pattern_15

Significance: 0.0005160830000000001

Pattern: motif7.motif

Significance: 7.69324e-07

Hnd_BRN;P0;D;En

Pattern: metacluster_1/pattern_3

Significance: 3.17943e-06

Pattern: motif8.motif

Significance: 0.0057712

wES;Md_BRN;E11.5;D;En

Pattern: metacluster_0/pattern_4

Significance: 0.00190359

Pattern: motif19.motif

Significance: 0.0117685

Md_BRN;D;En

Pattern: metacluster_1/pattern_5

Significance: 6.86542e-08

Pattern: motif15.motif

Significance: 0.00048278599999999997

wES;WHL_BRN;E14.5;D;En

Pattern: metacluster_1/pattern_5

Significance: 0.020850599999999997

/

Pattern: metacluster_1/pattern_6

Significance: 2.37345e-06

Pattern: motif10.motif

Significance: 0.00529895

WHL_BRN;8wks;D;En

Pattern: metacluster_1/pattern_4

Significance: 1.57746e-07

/

Pattern: metacluster_1/pattern_11

Significance: 0.0118303

Pattern: motif2.motif

Significance: 4.99049e-06

Unique Cell types only TF-MoDISco finds Neurod2: #36

Cell typeModiscoHomer
wES;Fr_lmb;E11.5;D;En

Pattern: metacluster_1/pattern_3

Significance: 0.018165200000000003

Absent
proB;A;CL

Pattern: metacluster_1/pattern_3

Significance: 0.0183299

Absent
preB;A;CL

Pattern: metacluster_1/pattern_4

Significance: 0.0148602

Absent
B1_B;A;CL

Pattern: metacluster_1/pattern_18

Significance: 0.04648819999999999

Absent
plasmaB;A;CL

Pattern: metacluster_1/pattern_5

Significance: 0.0235673

Absent
MN1;D;En

Pattern: metacluster_1/pattern_16

Significance: 0.0019285

Absent
GCN_PHT_RCPTR;A;GEO

Pattern: metacluster_1/pattern_13

Significance: 5.01621e-07

Absent
BL_CN_PHT_RCPTR;A;GEO

Pattern: metacluster_1/pattern_12

Significance: 1.71545e-05

Absent
CN_PHT_RCPTR;A;GEO

Pattern: metacluster_1/pattern_13

Significance: 8.491339999999999e-07

Absent
wES;3rd_Rhmbmr;E8.5;A;GEO

Pattern: metacluster_0/pattern_10

Significance: 0.00832723

Absent
npES;5th_Rhmbmr_delC;E8.5;A;GEO

Pattern: metacluster_1/pattern_21

Significance: 0.0101271

Absent
wES;5th_Rhmbmr;E9.5;A;GEO

Pattern: metacluster_0/pattern_15

Significance: 0.000263041

/

Pattern: metacluster_0/pattern_22

Significance: 5.4441300000000003e-05

Absent
wES;5th_Rhmbmr;E8.5;A;GEO

Pattern: metacluster_0/pattern_12

Significance: 0.00809087

/

Pattern: metacluster_0/pattern_22

Significance: 0.03938130000000001

Absent
npES;5th_Rhmbmr_delA;E8.5;A;GEO

Pattern: metacluster_0/pattern_5

Significance: 0.0452741

Absent
wES;posterior;1;E9.5;A;GEO

Pattern: metacluster_1/pattern_5

Significance: 0.000678804

Absent
wES;posterior;2;E9.5;A;GEO

Pattern: metacluster_0/pattern_9

Significance: 3.5132800000000004e-05

Absent
wES;posterior;1;E8.5;A;GEO

Pattern: metacluster_0/pattern_10

Significance: 0.00158966

Absent
npES;posterior_delA;E8.5;A;GEO

Pattern: metacluster_0/pattern_8

Significance: 0.00013022

Absent
npES;posterior_delC;E8.5;A;GEO

Pattern: metacluster_0/pattern_9

Significance: 0.00132272

Absent
ISP;A;CL

Pattern: metacluster_1/pattern_4

Significance: 0.0532009

Absent
G_NRN_P;A;GEO

Pattern: metacluster_1/pattern_0

Significance: 5.5438e-08

Absent
Corticotrope;A;GEO

Pattern: metacluster_0/pattern_17

Significance: 0.00633318

Absent
LNG;A;CL

Pattern: metacluster_1/pattern_20

Significance: 0.0138773

Absent
Muscle;A;CL

Pattern: metacluster_1/pattern_16

Significance: 0.0184132

Absent
Heart;D;En

Pattern: metacluster_0/pattern_8

Significance: 0.0132882

Absent
Melanotrope;A;GEO

Pattern: metacluster_0/pattern_8

Significance: 0.026027999999999996

Absent
BRN;OLFTRY_BLB;A;CL

Pattern: metacluster_0/pattern_13

Significance: 0.0128032

Absent
LNG;8wks;D;GEO

Pattern: metacluster_0/pattern_21

Significance: 0.0505402

Absent
KDNY;P0;D;En

Pattern: metacluster_1/pattern_9

Significance: 0.058551099999999995

Absent
LNG;8wks;D;En

Pattern: metacluster_0/pattern_17

Significance: 0.0338861

Absent
Heart;8wks;D;En

Pattern: metacluster_0/pattern_11

Significance: 0.0183927

Absent
RTN;A;GEO

Pattern: metacluster_0/pattern_6

Significance: 8.63439e-08

Absent
wES;Hnd_BRN;E11.5;D;En

Pattern: metacluster_0/pattern_4

Significance: 0.00042635599999999997

Absent
wES;Hnd_BRN;E14.5;D;En

Pattern: metacluster_0/pattern_7

Significance: 0.0177056

/

Pattern: metacluster_0/pattern_12

Significance: 8.74216e-06

Absent
wES;Md_BRN;E14.4;D;En

Pattern: metacluster_0/pattern_4

Significance: 0.00474469

Absent
wES;Telenchephalon;D;En

Pattern: metacluster_1/pattern_3

Significance: 1.0055899999999999e-06

Absent
Unique Cell types only Homer finds Neurod2: #5

Cell typeModiscoHomer
LNG;P0;D;EnAbsent

Pattern: motif18.motif

Significance: 0.0247202

wES;LNG;E14.5;D;EnAbsent

Pattern: motif13.motif

Significance: 0.0339809

wES;FaceP;E11.5;D;EnAbsent

Pattern: motif7.motif

Significance: 0.0531342

NPC;Ch13;A;GEOAbsent

Pattern: motif13.motif

Significance: 0.021347900000000003

DP3a;A;CLAbsent

Pattern: motif12.motif

Significance: 0.0453284