In [1]:
# Parameters
data_name = "Rxra"
task_idxs = "0-213,216-278"
homer_root = "/srv/scratch/msharmin/mouse_hem/with_tfd/full_mouse50/Naive_scans"
modisco_root = "/srv/scratch/msharmin/mouse_hem/with_tfd/full_mouse50/Naive_modisco2019"
overwrite = False
In [2]:
from matlas.reports import collect_motifDB_to_be_displayed, display_comparative_cell_types

load data from labcluster

Using TensorFlow backend.
2019-08-23 11:33:10,080 [WARNING] git-lfs not installed
In [3]:
homer_matches, modisco_matches = collect_motifDB_to_be_displayed(task_idxs, homer_root, modisco_root, 
                                                              overwrite=False)

TF-MoDISco is using the TensorFlow backend.
In [4]:
display_comparative_cell_types(data_name, homer_matches, modisco_matches)
Rxra: Motif: M09306_2.00



Forward PWM

Reverse PWM

Shared Cell types both TF-MoDISco and Homer finds Rxra: #25

Cell typeModiscoHomer
LRG_INTSTN;8wks;D;En

Pattern: metacluster_1/pattern_2

Significance: 1.25942e-05

Pattern: motif3.motif

Significance: 0.000366395

npES;3rd_Rhmbmr_delA;E8.5;A;GEO

Pattern: metacluster_0/pattern_15

Significance: 0.0194509

/

Pattern: metacluster_0/pattern_17

Significance: 0.0204259

Pattern: motif20.motif

Significance: 3.71626e-07

wES;3rd_Rhmbmr;E8.5;A;GEO

Pattern: metacluster_0/pattern_14

Significance: 0.053231600000000004

/

Pattern: metacluster_0/pattern_17

Significance: 0.026598300000000002

Pattern: motif12.motif

Significance: 0.0448941

npES;3rd_Rhmbmr_delC;E8.5;A;GEO

Pattern: metacluster_0/pattern_13

Significance: 0.0542436

/

Pattern: metacluster_0/pattern_16

Significance: 0.014999700000000001

/

Pattern: metacluster_0/pattern_18

Significance: 0.050287599999999995

Pattern: motif15.motif

Significance: 0.03524

wES;5th_Rhmbmr;E9.5;A;GEO

Pattern: metacluster_0/pattern_10

Significance: 0.0146909

Pattern: motif9.motif

Significance: 0.030509699999999997

wES;5th_Rhmbmr;E8.5;A;GEO

Pattern: metacluster_0/pattern_5

Significance: 0.00660366

/

Pattern: metacluster_0/pattern_24

Significance: 0.0497766

Pattern: motif17.motif

Significance: 0.0391305

npES;5th_Rhmbmr_delA;E8.5;A;GEO

Pattern: metacluster_0/pattern_14

Significance: 0.0460619

/

Pattern: metacluster_0/pattern_17

Significance: 0.0176712

Pattern: motif18.motif

Significance: 7.59551e-07

wES;posterior;1;E9.5;A;GEO

Pattern: metacluster_1/pattern_12

Significance: 0.00555084

Pattern: motif8.motif

Significance: 0.048524300000000006

wES;posterior;2;E9.5;A;GEO

Pattern: metacluster_0/pattern_8

Significance: 0.0572819

/

Pattern: metacluster_0/pattern_15

Significance: 0.0182479

Pattern: motif9.motif

Significance: 0.029793200000000002

SML_INTSTN;A;CL

Pattern: metacluster_0/pattern_3

Significance: 1.10026e-05

Pattern: motif5.motif

Significance: 0.00626326

LRG_INTSTN;A;CL

Pattern: metacluster_0/pattern_1

Significance: 4.51962e-05

Pattern: motif2.motif

Significance: 0.00531345

npES;ZHBTC4;doxyc;treat;A;GEO

Pattern: metacluster_0/pattern_13

Significance: 0.000217455

Pattern: motif14.motif

Significance: 0.00506632

npES;ZHBTC4;Brg1fl_fl;untreat;A;GEO

Pattern: metacluster_1/pattern_23

Significance: 0.0317265

Pattern: motif32.motif

Significance: 0.0510919

Adrenal;A;CL

Pattern: metacluster_1/pattern_0

Significance: 0.000343055

/

Pattern: metacluster_1/pattern_15

Significance: 0.054765499999999995

Pattern: motif2.motif

Significance: 2.00159e-05

placenta;A;CL

Pattern: metacluster_0/pattern_11

Significance: 0.054093499999999996

Pattern: motif12.motif

Significance: 1.1398299999999999e-08

ES;ZhBTc4;1;D;GEO

Pattern: metacluster_1/pattern_11

Significance: 0.00814486

Pattern: motif14.motif

Significance: 0.029466700000000002

ES;ZhBTc4;2;D;GEO

Pattern: metacluster_1/pattern_12

Significance: 0.000136738

Pattern: motif12.motif

Significance: 0.00420516

ES;D0;D;GEO

Pattern: metacluster_0/pattern_10

Significance: 0.014266399999999999

Pattern: motif14.motif

Significance: 0.00899205

LVR;8wks;D;GEO

Pattern: metacluster_1/pattern_0

Significance: 5.32854e-07

/

Pattern: metacluster_1/pattern_17

Significance: 0.0165078

Pattern: motif1.motif

Significance: 3.4483499999999996e-05

ES;129S1_SVImJ_CJ7;D;En

Pattern: metacluster_1/pattern_9

Significance: 0.0479774

Pattern: motif18.motif

Significance: 0.002876

ES;C57BL_6J;R1;D;En

Pattern: metacluster_1/pattern_13

Significance: 0.015365100000000001

Pattern: motif22.motif

Significance: 0.000371962

KDNY;8wks;D;En

Pattern: metacluster_1/pattern_1

Significance: 0.052090599999999994

Pattern: motif2.motif

Significance: 9.599120000000001e-05

LVR;8wks;D;En

Pattern: metacluster_0/pattern_0

Significance: 8.444370000000001e-07

Pattern: motif2.motif

Significance: 2.46488e-05

Adipocyte_3T3-L1D;C57BL6;D8;D;En

Pattern: metacluster_1/pattern_9

Significance: 4.864560000000001e-05

Pattern: motif10.motif

Significance: 6.42241e-05

wES;MSDRM;E11.5;D;En

Pattern: metacluster_0/pattern_11

Significance: 0.015616399999999999

Pattern: motif19.motif

Significance: 4.21619e-07

Unique Cell types only TF-MoDISco finds Rxra: #31

Cell typeModiscoHomer
T_MLD;TCR_SV40-I_CD8+;D28;A;GEO

Pattern: metacluster_1/pattern_17

Significance: 0.0433176

Absent
wES;limb;E11.5;D;En

Pattern: metacluster_0/pattern_16

Significance: 0.058220100000000004

Absent
wES;Hnd_lmb;E11.5;D;En

Pattern: metacluster_0/pattern_22

Significance: 0.0198445

/

Pattern: metacluster_0/pattern_23

Significance: 0.0140815

Absent
memT_tmrD_lstr;TCR_SV40-I_CD8+;D14;A;GEO

Pattern: metacluster_0/pattern_17

Significance: 0.0252319

Absent
memT_tmrD;TCR_SV40-I_CD8+;D14;A;GEO

Pattern: metacluster_1/pattern_16

Significance: 0.05942240000000001

Absent
STMCH;P0;D;En

Pattern: metacluster_1/pattern_11

Significance: 0.00548274

Absent
416B;HMTP_SPNSN;CD34+;D;En

Pattern: metacluster_1/pattern_18

Significance: 0.0331756

Absent
MEL;D;En

Pattern: metacluster_1/pattern_13

Significance: 0.0546433

Absent
Tfr_mut;CD4+CD44+CXCR5+PD1+CD25+;A;CL

Pattern: metacluster_1/pattern_17

Significance: 0.0579774

Absent
npES;5th_Rhmbmr_delC;E8.5;A;GEO

Pattern: metacluster_1/pattern_8

Significance: 0.00776046

Absent
wES;posterior;1;E8.5;A;GEO

Pattern: metacluster_0/pattern_21

Significance: 0.0505392

/

Pattern: metacluster_0/pattern_24

Significance: 0.0376525

Absent
npES;posterior_delA;E8.5;A;GEO

Pattern: metacluster_0/pattern_13

Significance: 0.00296889

Absent
npES;posterior_delC;E8.5;A;GEO

Pattern: metacluster_0/pattern_20

Significance: 0.0307166

/

Pattern: metacluster_0/pattern_21

Significance: 0.029841000000000003

/

Pattern: metacluster_0/pattern_22

Significance: 0.0407977

Absent
CD4+CD8-TCR+CD25-Foxp3+;A;CL

Pattern: metacluster_1/pattern_23

Significance: 0.043972699999999997

Absent
CD4+CD8-TCR+CD25+Foxp3+;A;CL

Pattern: metacluster_1/pattern_14

Significance: 0.0520505

Absent
ThMS_MEC;Aire++;A;GEO

Pattern: metacluster_1/pattern_16

Significance: 0.00237246

Absent
Muscle;A;CL

Pattern: metacluster_1/pattern_21

Significance: 0.0367901

Absent
pCMP;A;CL

Pattern: metacluster_1/pattern_16

Significance: 0.0345097

Absent
416B_MP;CD34+;D;GEO

Pattern: metacluster_1/pattern_19

Significance: 0.00748905

Absent
ES;E14;D;En

Pattern: metacluster_1/pattern_15

Significance: 0.010334999999999999

/

Pattern: metacluster_1/pattern_19

Significance: 0.0125492

Absent
KDNY;P0;D;En

Pattern: metacluster_1/pattern_23

Significance: 0.00020060599999999998

Absent
wES;LVR;E11.5;D.;En

Pattern: metacluster_1/pattern_15

Significance: 0.044206800000000004

Absent
ES;J1;A;CL

Pattern: metacluster_1/pattern_12

Significance: 0.0222415

Absent
LVR;P0;D;En

Pattern: metacluster_1/pattern_10

Significance: 0.054486400000000004

Absent
ES;129SV_Jae_C57BL6J;A;GEO

Pattern: metacluster_1/pattern_15

Significance: 0.0249739

Absent
Heart;8wks;D;En

Pattern: metacluster_0/pattern_16

Significance: 0.0284946

Absent
Heart;P0;D;En

Pattern: metacluster_1/pattern_19

Significance: 0.00671941

Absent
naiveT;CD8+;A;GEO

Pattern: metacluster_1/pattern_11

Significance: 0.0528096

Absent
416B_MP;CD34+;D;En

Pattern: metacluster_1/pattern_20

Significance: 2.6458300000000003e-07

Absent
T_LCMV;CD8+;D35;A;GEO

Pattern: metacluster_1/pattern_16

Significance: 0.040009300000000005

Absent
naiveT;trnsgncTCR_SV40-I_CD8;A;GEO

Pattern: metacluster_0/pattern_10

Significance: 0.033262599999999996

Absent
Unique Cell types only Homer finds Rxra: #2

Cell typeModiscoHomer
DC_BMD;A;CLAbsent

Pattern: motif13.motif

Significance: 0.026607799999999997

ES;ZhBTc4;untreated;A;GEOAbsent

Pattern: motif19.motif

Significance: 0.053002