In [1]:
# Parameters
data_name = "Pknox2"
task_idxs = "0-213,216-278"
homer_root = "/srv/scratch/msharmin/mouse_hem/with_tfd/full_mouse50/Naive_scans"
modisco_root = "/srv/scratch/msharmin/mouse_hem/with_tfd/full_mouse50/Naive_modisco2019"
overwrite = False
In [2]:
from matlas.reports import collect_motifDB_to_be_displayed, display_comparative_cell_types

load data from labcluster

Using TensorFlow backend.
2019-08-23 11:28:21,759 [WARNING] git-lfs not installed
In [3]:
homer_matches, modisco_matches = collect_motifDB_to_be_displayed(task_idxs, homer_root, modisco_root, 
                                                              overwrite=False)

TF-MoDISco is using the TensorFlow backend.
In [4]:
display_comparative_cell_types(data_name, homer_matches, modisco_matches)
Pknox2: Motif: M03270_2.00



Forward PWM

Reverse PWM

Shared Cell types both TF-MoDISco and Homer finds Pknox2: #8

Cell typeModiscoHomer
largeDPprecrsr;CD4+CD8+CD69-;A;CL

Pattern: metacluster_1/pattern_5

Significance: 0.0209517

Pattern: motif18.motif

Significance: 0.0588486

proB;A;CL

Pattern: metacluster_1/pattern_3

Significance: 0.00930468

Pattern: motif15.motif

Significance: 0.0142208

preB_BMD;A;GEO

Pattern: metacluster_1/pattern_5

Significance: 0.024110299999999998

Pattern: motif9.motif

Significance: 0.028002199999999998

plasmaB;A;CL

Pattern: metacluster_1/pattern_5

Significance: 0.00220067

Pattern: motif9.motif

Significance: 0.0113916

DP;A;CL

Pattern: metacluster_1/pattern_10

Significance: 0.013592600000000002

Pattern: motif17.motif

Significance: 0.0474719

B;B220_CD43;A;GEO

Pattern: metacluster_1/pattern_9

Significance: 0.0219765

Pattern: motif11.motif

Significance: 0.0315226

ISP;A;CL

Pattern: metacluster_1/pattern_4

Significance: 0.0469596

Pattern: motif14.motif

Significance: 0.039109500000000005

Muscle;A;CL

Pattern: metacluster_1/pattern_16

Significance: 0.03435119999999999

Pattern: motif19.motif

Significance: 0.013110499999999999

Unique Cell types only TF-MoDISco finds Pknox2: #13

Cell typeModiscoHomer
wES;5th_Rhmbmr;E8.5;A;GEO

Pattern: metacluster_0/pattern_12

Significance: 0.010460899999999999

Absent
smallDPprecrsor;CD4+CD8+CD69-;A;CL

Pattern: metacluster_1/pattern_4

Significance: 0.013636500000000001

Absent
wES;posterior;2;E9.5;A;GEO

Pattern: metacluster_0/pattern_9

Significance: 0.048601

/

Pattern: metacluster_0/pattern_13

Significance: 0.0286546

Absent
wES;posterior;1;E8.5;A;GEO

Pattern: metacluster_0/pattern_10

Significance: 0.027538599999999996

Absent
BRN;PTMN;A;CL

Pattern: metacluster_1/pattern_15

Significance: 0.032563

Absent
npES;posterior_delC;E8.5;A;GEO

Pattern: metacluster_0/pattern_9

Significance: 0.041798300000000004

Absent
Heart;P0;D;En

Pattern: metacluster_1/pattern_15

Significance: 0.0327039

Absent
wES;Md_BRN;E11.5;D;En

Pattern: metacluster_0/pattern_4

Significance: 0.0531658

Absent
DP3b;A;CL

Pattern: metacluster_1/pattern_3

Significance: 0.029129900000000004

Absent
wES;Md_BRN;E14.4;D;En

Pattern: metacluster_0/pattern_4

Significance: 0.046441199999999995

Absent
npES;3rd_Rhmbmr_delA;E8.5;A;GEO

Pattern: metacluster_0/pattern_24

Significance: 0.020783700000000002

Absent
wES;3rd_Rhmbmr;E8.5;A;GEO

Pattern: metacluster_0/pattern_10

Significance: 0.0317823

/

Pattern: metacluster_0/pattern_19

Significance: 0.00740572

Absent
npES;5th_Rhmbmr_delC;E8.5;A;GEO

Pattern: metacluster_1/pattern_21

Significance: 0.033488199999999996

Absent
Unique Cell types only Homer finds Pknox2: #12

Cell typeModiscoHomer
LNG;P0;D;EnAbsent

Pattern: motif18.motif

Significance: 0.010174299999999999

preB;A;CLAbsent

Pattern: motif12.motif

Significance: 0.0130493

Heart;8wks;D;EnAbsent

Pattern: motif11.motif

Significance: 0.0380921

SKLTL_Muscle;8wks;D;EnAbsent

Pattern: motif10.motif

Significance: 0.0180193

NPC;F129;A;GEOAbsent

Pattern: motif10.motif

Significance: 0.0307268

NPC;G4;A;GEOAbsent

Pattern: motif9.motif

Significance: 0.050468

NPC;Ch13;A;GEOAbsent

Pattern: motif13.motif

Significance: 0.0224112

NPC;mE6;A;GEOAbsent

Pattern: motif11.motif

Significance: 0.0227774

DP3a;A;CLAbsent

Pattern: motif12.motif

Significance: 0.0212048

G_NRN_P;A;GEOAbsent

Pattern: motif5.motif

Significance: 0.0189871

ThMS_MEC;Aire++;A;GEOAbsent

Pattern: motif12.motif

Significance: 0.0100377

Heart;D;EnAbsent

Pattern: motif13.motif

Significance: 0.054621800000000005