In [1]:
# Parameters
data_name = "Esrra"
task_idxs = "0-213,216-278"
homer_root = "/srv/scratch/msharmin/mouse_hem/with_tfd/full_mouse50/Naive_scans"
modisco_root = "/srv/scratch/msharmin/mouse_hem/with_tfd/full_mouse50/Naive_modisco2019"
overwrite = False
In [2]:
from matlas.reports import collect_motifDB_to_be_displayed, display_comparative_cell_types

load data from labcluster

Using TensorFlow backend.
2019-08-23 11:05:21,647 [WARNING] git-lfs not installed
In [3]:
homer_matches, modisco_matches = collect_motifDB_to_be_displayed(task_idxs, homer_root, modisco_root, 
                                                              overwrite=False)

TF-MoDISco is using the TensorFlow backend.
In [4]:
display_comparative_cell_types(data_name, homer_matches, modisco_matches)
Esrra: Motif: M00183_2.00



Forward PWM

Reverse PWM

Shared Cell types both TF-MoDISco and Homer finds Esrra: #17

Cell typeModiscoHomer
wES;5th_Rhmbmr;E8.5;A;GEO

Pattern: metacluster_0/pattern_5

Significance: 0.0371827

Pattern: motif17.motif

Significance: 0.0585855

npES;5th_Rhmbmr_delA;E8.5;A;GEO

Pattern: metacluster_0/pattern_17

Significance: 0.0490172

Pattern: motif18.motif

Significance: 0.0486814

LVR;8wks;D;En

Pattern: metacluster_0/pattern_0

Significance: 0.0589813

Pattern: motif2.motif

Significance: 0.0323212

npES;ZHBTC4;Brg1fl_fl;untreat;A;GEO

Pattern: metacluster_1/pattern_23

Significance: 0.000170542

Pattern: motif32.motif

Significance: 0.000605877

ES;ZhBTc4;1;D;GEO

Pattern: metacluster_1/pattern_11

Significance: 0.00665896

Pattern: motif14.motif

Significance: 0.0200965

ES;ZhBTc4;2;D;GEO

Pattern: metacluster_1/pattern_12

Significance: 0.00246512

Pattern: motif12.motif

Significance: 0.00364064

ES;D0;D;GEO

Pattern: metacluster_0/pattern_10

Significance: 0.00323272

Pattern: motif14.motif

Significance: 0.0283921

Adipocyte_3T3-L1D;C57BL6;D8;D;En

Pattern: metacluster_1/pattern_9

Significance: 0.05160940000000001

Pattern: motif10.motif

Significance: 0.0257789

LVR;8wks;D;GEO

Pattern: metacluster_1/pattern_0

Significance: 0.0505556

/

Pattern: metacluster_1/pattern_17

Significance: 0.0314123

Pattern: motif1.motif

Significance: 0.0524308

/

Pattern: motif5.motif

Significance: 0.054644399999999996

wES;MSDRM;E11.5;D;En

Pattern: metacluster_0/pattern_11

Significance: 0.0567341

Pattern: motif19.motif

Significance: 0.05950219999999999

ES;ZhBTc4;untreated;A;GEO

Pattern: metacluster_1/pattern_10

Significance: 0.00798045

Pattern: motif19.motif

Significance: 0.000626754

npES;ZHBTC4;doxyc;treat;A;GEO

Pattern: metacluster_0/pattern_13

Significance: 0.00294427

Pattern: motif14.motif

Significance: 0.00399023

ES;E14;D;En

Pattern: metacluster_1/pattern_15

Significance: 0.00127931

/

Pattern: metacluster_1/pattern_19

Significance: 0.0130183

Pattern: motif23.motif

Significance: 0.0585054

ES;C57BL_6J;R1;D;En

Pattern: metacluster_1/pattern_13

Significance: 0.00599943

Pattern: motif22.motif

Significance: 0.011923999999999999

Adrenal;A;CL

Pattern: metacluster_1/pattern_0

Significance: 0.00353731

/

Pattern: metacluster_1/pattern_15

Significance: 0.00536373

Pattern: motif2.motif

Significance: 0.022544099999999997

placenta;A;CL

Pattern: metacluster_0/pattern_11

Significance: 0.0562887

Pattern: motif12.motif

Significance: 0.05183340000000001

ES;129S1_SVImJ_CJ7;D;En

Pattern: metacluster_1/pattern_9

Significance: 0.00724286

Pattern: motif18.motif

Significance: 0.00594773

Unique Cell types only TF-MoDISco finds Esrra: #26

Cell typeModiscoHomer
T_MLD;TCR_SV40-I_CD8+;D28;A;GEO

Pattern: metacluster_1/pattern_17

Significance: 0.0336213

Absent
wES;Hnd_lmb;E11.5;D;En

Pattern: metacluster_0/pattern_22

Significance: 0.0526048

/

Pattern: metacluster_0/pattern_23

Significance: 0.039338099999999994

Absent
memT_tmrD_lstr;TCR_SV40-I_CD8+;D14;A;GEO

Pattern: metacluster_0/pattern_17

Significance: 0.0235926

Absent
memT_tmrD;TCR_SV40-I_CD8+;D14;A;GEO

Pattern: metacluster_1/pattern_16

Significance: 0.058513800000000005

Absent
416B;HMTP_SPNSN;CD34+;D;En

Pattern: metacluster_1/pattern_18

Significance: 0.000566855

Absent
npES;3rd_Rhmbmr_delA;E8.5;A;GEO

Pattern: metacluster_0/pattern_17

Significance: 0.049759899999999996

Absent
Tfr_mut;CD4+CD44+CXCR5+PD1+CD25+;A;CL

Pattern: metacluster_1/pattern_17

Significance: 0.038095300000000006

Absent
npES;3rd_Rhmbmr_delC;E8.5;A;GEO

Pattern: metacluster_0/pattern_16

Significance: 0.0442209

Absent
wES;posterior;1;E9.5;A;GEO

Pattern: metacluster_1/pattern_12

Significance: 0.0248822

Absent
wES;posterior;2;E9.5;A;GEO

Pattern: metacluster_0/pattern_8

Significance: 0.0202853

/

Pattern: metacluster_0/pattern_15

Significance: 0.0531196

Absent
wES;posterior;1;E8.5;A;GEO

Pattern: metacluster_0/pattern_21

Significance: 0.0528722

Absent
npES;posterior_delC;E8.5;A;GEO

Pattern: metacluster_0/pattern_20

Significance: 0.028584699999999998

/

Pattern: metacluster_0/pattern_24

Significance: 0.039072699999999995

Absent
CD4+CD8-TCR+CD25-Foxp3+;A;CL

Pattern: metacluster_1/pattern_23

Significance: 0.043972699999999997

Absent
ES;E14;A;CL

Pattern: metacluster_1/pattern_16

Significance: 0.042943699999999994

Absent
SML_INTSTN;A;CL

Pattern: metacluster_0/pattern_3

Significance: 0.0585793

Absent
Muscle;A;CL

Pattern: metacluster_1/pattern_21

Significance: 0.0267154

Absent
416B_MP;CD34+;D;GEO

Pattern: metacluster_1/pattern_19

Significance: 0.0187401

Absent
KDNY;P0;D;En

Pattern: metacluster_1/pattern_23

Significance: 0.0446582

Absent
KDNY;8wks;D;En

Pattern: metacluster_1/pattern_1

Significance: 0.030906700000000002

Absent
wES;LVR;E11.5;D.;En

Pattern: metacluster_1/pattern_15

Significance: 0.0404143

Absent
ES;J1;A;CL

Pattern: metacluster_1/pattern_12

Significance: 0.000156777

Absent
ES;129SV_Jae_C57BL6J;A;GEO

Pattern: metacluster_1/pattern_15

Significance: 0.0101698

Absent
Heart;8wks;D;En

Pattern: metacluster_0/pattern_16

Significance: 0.0198443

Absent
Heart;P0;D;En

Pattern: metacluster_1/pattern_19

Significance: 0.00412353

Absent
416B_MP;CD34+;D;En

Pattern: metacluster_1/pattern_20

Significance: 0.012229

Absent
T_LCMV;CD8+;D35;A;GEO

Pattern: metacluster_1/pattern_16

Significance: 0.0338077

Absent
No Cell types only Homer finds Esrra