In [1]:
# Parameters
data_name = "Pax6"
task_idxs = "0-213,216-278"
homer_root = "/srv/scratch/msharmin/mouse_hem/with_tfd/full_mouse50/Naive_scans"
modisco_root = "/srv/scratch/msharmin/mouse_hem/with_tfd/full_mouse50/Naive_modisco2019"
overwrite = False
In [2]:
from matlas.reports import collect_motifDB_to_be_displayed, display_comparative_cell_types

load data from labcluster

Using TensorFlow backend.
2019-08-23 11:27:20,099 [WARNING] git-lfs not installed
In [3]:
homer_matches, modisco_matches = collect_motifDB_to_be_displayed(task_idxs, homer_root, modisco_root, 
                                                              overwrite=False)

TF-MoDISco is using the TensorFlow backend.
In [4]:
display_comparative_cell_types(data_name, homer_matches, modisco_matches)
Pax6: Motif: M09217_2.00



Forward PWM

Reverse PWM

Shared Cell types both TF-MoDISco and Homer finds Pax6: #23

Cell typeModiscoHomer
wES;limb;E11.5;D;En

Pattern: metacluster_0/pattern_3

Significance: 0.00037004599999999996

Pattern: motif4.motif

Significance: 0.0149416

wES;Fr_lmb;E11.5;D;En

Pattern: metacluster_1/pattern_13

Significance: 0.000279442

Pattern: motif5.motif

Significance: 0.0327343

wES;Hnd_lmb;E11.5;D;En

Pattern: metacluster_0/pattern_3

Significance: 0.00025361599999999997

Pattern: motif3.motif

Significance: 0.0121487

wES;FaceP;E14.5;D;En

Pattern: metacluster_0/pattern_7

Significance: 0.029881

Pattern: motif14.motif

Significance: 0.047305

wES;FaceP;E11.5;D;En

Pattern: metacluster_1/pattern_4

Significance: 0.0389334

Pattern: motif3.motif

Significance: 0.0422324

MTR_NRN_MN1;methyl3;D;En

Pattern: metacluster_0/pattern_3

Significance: 0.0449756

Pattern: motif6.motif

Significance: 0.00983451

MN1;D;En

Pattern: metacluster_1/pattern_9

Significance: 0.058918700000000004

Pattern: motif9.motif

Significance: 0.0205497

BL_CN_PHT_RCPTR;A;GEO

Pattern: metacluster_1/pattern_18

Significance: 0.025704200000000003

Pattern: motif13.motif

Significance: 0.013153999999999999

wES;3rd_Rhmbmr;E8.5;A;GEO

Pattern: metacluster_0/pattern_21

Significance: 0.00117921

/

Pattern: metacluster_0/pattern_29

Significance: 0.013824200000000002

Pattern: motif16.motif

Significance: 0.0145399

BCK_SKN;A;GEO

Pattern: metacluster_0/pattern_6

Significance: 0.000320532

Pattern: motif9.motif

Significance: 0.00678937

iVIP_NRN;A;GEO

Pattern: metacluster_1/pattern_6

Significance: 0.055126699999999994

Pattern: motif3.motif

Significance: 0.0209787

G_NRN_P;A;GEO

Pattern: metacluster_1/pattern_14

Significance: 0.00246929

Pattern: motif13.motif

Significance: 0.00847391

wES;WHL_BRN;E14.5;D;GEO

Pattern: metacluster_0/pattern_0

Significance: 0.00033555900000000003

Pattern: motif2.motif

Significance: 0.00739831

CRBL_GRNL_Precrsr;A;GEO

Pattern: metacluster_0/pattern_6

Significance: 0.00178193

/

Pattern: metacluster_0/pattern_10

Significance: 1.05507e-07

Pattern: motif6.motif

Significance: 0.0165333

RTN;D1;D;En

Pattern: metacluster_0/pattern_3

Significance: 0.00154164

/

Pattern: metacluster_0/pattern_18

Significance: 0.0024835

/

Pattern: metacluster_0/pattern_22

Significance: 0.000851828

Pattern: motif2.motif

Significance: 0.00545761

wES;RTN;E11.5;D;En

Pattern: metacluster_0/pattern_1

Significance: 0.000879637

/

Pattern: metacluster_0/pattern_11

Significance: 9.26515e-07

Pattern: motif3.motif

Significance: 0.00723907

Muller;P12;D;En

Pattern: metacluster_1/pattern_5

Significance: 0.00243484

Pattern: motif4.motif

Significance: 0.00476655

wES.Fr_BRN;E14.4;D;En

Pattern: metacluster_0/pattern_2

Significance: 0.00030598

Pattern: motif2.motif

Significance: 0.00482473

Fr_BRN;P0;D;En

Pattern: metacluster_1/pattern_10

Significance: 0.021721400000000002

Pattern: motif10.motif

Significance: 0.0165168

wES;Hnd_BRN;E14.5;D;En

Pattern: metacluster_0/pattern_3

Significance: 0.0239296

/

Pattern: metacluster_0/pattern_8

Significance: 0.00187854

Pattern: motif3.motif

Significance: 0.0105771

wES;Md_BRN;E14.4;D;En

Pattern: metacluster_0/pattern_6

Significance: 0.000428084

Pattern: motif6.motif

Significance: 0.015593000000000001

Md_BRN;D;En

Pattern: metacluster_1/pattern_3

Significance: 0.00110348

Pattern: motif14.motif

Significance: 0.00284529

wES;WHL_BRN;E14.5;D;En

Pattern: metacluster_1/pattern_0

Significance: 0.000262199

Pattern: motif2.motif

Significance: 0.00693675

Unique Cell types only TF-MoDISco finds Pax6: #25

Cell typeModiscoHomer
preB;A;CL

Pattern: metacluster_1/pattern_19

Significance: 0.00032229

/

Pattern: metacluster_1/pattern_20

Significance: 0.000397901

Absent
aB;A;GEO

Pattern: metacluster_1/pattern_23

Significance: 0.000437722

/

Pattern: metacluster_1/pattern_25

Significance: 0.00263991

Absent
GC_B;A;CL

Pattern: metacluster_1/pattern_8

Significance: 0.00016398

Absent
preB_BMD;A;GEO

Pattern: metacluster_1/pattern_14

Significance: 0.00013147

Absent
B;B220_CD43;A;GEO

Pattern: metacluster_1/pattern_19

Significance: 4.8461800000000004e-05

Absent
npES;3rd_Rhmbmr_delA;E8.5;A;GEO

Pattern: metacluster_0/pattern_16

Significance: 0.00223894

Absent
npES;3rd_Rhmbmr_delC;E8.5;A;GEO

Pattern: metacluster_0/pattern_14

Significance: 0.00195994

Absent
wES;5th_Rhmbmr;E9.5;A;GEO

Pattern: metacluster_0/pattern_21

Significance: 0.0346034

Absent
wES;5th_Rhmbmr;E8.5;A;GEO

Pattern: metacluster_0/pattern_22

Significance: 0.046337800000000005

/

Pattern: metacluster_0/pattern_25

Significance: 0.00413228

Absent
npES;5th_Rhmbmr_delA;E8.5;A;GEO

Pattern: metacluster_0/pattern_20

Significance: 0.00741547

Absent
wES;posterior;2;E9.5;A;GEO

Pattern: metacluster_0/pattern_21

Significance: 0.000718534

Absent
wES;posterior;1;E8.5;A;GEO

Pattern: metacluster_0/pattern_18

Significance: 0.00464817

Absent
npES;posterior_delA;E8.5;A;GEO

Pattern: metacluster_0/pattern_6

Significance: 0.053784900000000004

Absent
npES;posterior_delC;E8.5;A;GEO

Pattern: metacluster_0/pattern_6

Significance: 0.000908238

Absent
NPC;G4;A;GEO

Pattern: metacluster_1/pattern_18

Significance: 0.0309618

Absent
NPC;mE6;A;GEO

Pattern: metacluster_1/pattern_9

Significance: 0.0403923

Absent
iPV_NRN;A;GEO

Pattern: metacluster_1/pattern_7

Significance: 0.033007199999999993

Absent
npES;ZHBTC4;Brg1fl_fl;untreat;A;GEO

Pattern: metacluster_1/pattern_21

Significance: 0.0346939

Absent
aB_LPS+IL4+Oligomycin_24h;A;CL

Pattern: metacluster_1/pattern_24

Significance: 0.00372978

Absent
ES;C57BL_6J;R1;D;En

Pattern: metacluster_1/pattern_19

Significance: 0.033016199999999996

Absent
KDNY;8wks;D;En

Pattern: metacluster_1/pattern_16

Significance: 6.54438e-05

/

Pattern: metacluster_1/pattern_18

Significance: 0.00564423

Absent
ES;E14;A;GEO

Pattern: metacluster_0/pattern_19

Significance: 0.038042599999999996

Absent
ES;v6.5;A;GEO

Pattern: metacluster_1/pattern_16

Significance: 0.0399505

Absent
wES;MSDRM;E11.5;D;En

Pattern: metacluster_0/pattern_5

Significance: 0.00629848

Absent
Hnd_BRN;P0;D;En

Pattern: metacluster_1/pattern_6

Significance: 0.000579601

Absent
Unique Cell types only Homer finds Pax6: #3

Cell typeModiscoHomer
wES.CRNL_NRL_CRST;E10.5;A;GEOAbsent

Pattern: motif3.motif

Significance: 0.0394848

CN_PHT_RCPTR;A;GEOAbsent

Pattern: motif8.motif

Significance: 0.012446899999999999

Melanotrope;A;GEOAbsent

Pattern: motif17.motif

Significance: 0.011949