In [1]:
# Parameters
data_name = "Nr4a2"
task_idxs = "0-213,216-278"
homer_root = "/srv/scratch/msharmin/mouse_hem/with_tfd/full_mouse50/Naive_scans"
modisco_root = "/srv/scratch/msharmin/mouse_hem/with_tfd/full_mouse50/Naive_modisco2019"
overwrite = False
In [2]:
from matlas.reports import collect_motifDB_to_be_displayed, display_comparative_cell_types

load data from labcluster

Using TensorFlow backend.
2019-08-23 11:25:55,754 [WARNING] git-lfs not installed
In [3]:
homer_matches, modisco_matches = collect_motifDB_to_be_displayed(task_idxs, homer_root, modisco_root, 
                                                              overwrite=False)

TF-MoDISco is using the TensorFlow backend.
In [4]:
display_comparative_cell_types(data_name, homer_matches, modisco_matches)
Nr4a2: Motif: M09323_2.00



Forward PWM

Reverse PWM

Shared Cell types both TF-MoDISco and Homer finds Nr4a2: #18

Cell typeModiscoHomer
wES;5th_Rhmbmr;E8.5;A;GEO

Pattern: metacluster_0/pattern_5

Significance: 0.00369894

Pattern: motif17.motif

Significance: 0.0208571

npES;5th_Rhmbmr_delA;E8.5;A;GEO

Pattern: metacluster_0/pattern_14

Significance: 0.0288577

/

Pattern: metacluster_0/pattern_17

Significance: 0.0170547

Pattern: motif18.motif

Significance: 0.021411700000000002

LVR;8wks;D;En

Pattern: metacluster_0/pattern_0

Significance: 0.017383000000000003

Pattern: motif2.motif

Significance: 0.017292500000000002

wES;posterior;2;E9.5;A;GEO

Pattern: metacluster_0/pattern_8

Significance: 0.00114171

/

Pattern: metacluster_0/pattern_15

Significance: 0.0189712

Pattern: motif9.motif

Significance: 0.051748699999999995

ES;ZhBTc4;1;D;GEO

Pattern: metacluster_1/pattern_11

Significance: 0.0425396

Pattern: motif14.motif

Significance: 0.0400087

ES;ZhBTc4;2;D;GEO

Pattern: metacluster_1/pattern_12

Significance: 0.0394704

Pattern: motif12.motif

Significance: 0.0465482

ES;D0;D;GEO

Pattern: metacluster_0/pattern_10

Significance: 0.0350154

Pattern: motif14.motif

Significance: 0.024712599999999998

Adipocyte_3T3-L1D;C57BL6;D8;D;En

Pattern: metacluster_1/pattern_9

Significance: 0.00936991

Pattern: motif10.motif

Significance: 0.00991026

LVR;8wks;D;GEO

Pattern: metacluster_1/pattern_0

Significance: 0.018159599999999998

Pattern: motif1.motif

Significance: 0.023449599999999998

LRG_INTSTN;8wks;D;En

Pattern: metacluster_1/pattern_2

Significance: 0.058385900000000004

Pattern: motif3.motif

Significance: 0.027571

wES;MSDRM;E11.5;D;En

Pattern: metacluster_0/pattern_11

Significance: 0.051011400000000005

Pattern: motif19.motif

Significance: 0.0199543

placenta;A;CL

Pattern: metacluster_0/pattern_11

Significance: 0.00904131

Pattern: motif12.motif

Significance: 0.015707299999999997

npES;ZHBTC4;doxyc;treat;A;GEO

Pattern: metacluster_0/pattern_13

Significance: 0.0366399

Pattern: motif14.motif

Significance: 0.0293774

npES;ZHBTC4;Brg1fl_fl;untreat;A;GEO

Pattern: metacluster_1/pattern_23

Significance: 0.0108415

Pattern: motif32.motif

Significance: 0.0279337

npES;3rd_Rhmbmr_delA;E8.5;A;GEO

Pattern: metacluster_0/pattern_15

Significance: 0.00376565

/

Pattern: metacluster_0/pattern_17

Significance: 0.0204259

Pattern: motif20.motif

Significance: 0.0188915

ES;129S1_SVImJ_CJ7;D;En

Pattern: metacluster_1/pattern_9

Significance: 0.0450084

Pattern: motif18.motif

Significance: 0.0480607

npES;3rd_Rhmbmr_delC;E8.5;A;GEO

Pattern: metacluster_0/pattern_13

Significance: 0.0232477

/

Pattern: metacluster_0/pattern_16

Significance: 0.014550200000000001

Pattern: motif15.motif

Significance: 0.03524

KDNY;8wks;D;En

Pattern: metacluster_1/pattern_1

Significance: 0.010793

Pattern: motif2.motif

Significance: 0.024848099999999998

Unique Cell types only TF-MoDISco finds Nr4a2: #30

Cell typeModiscoHomer
T_MLD;TCR_SV40-I_CD8+;D28;A;GEO

Pattern: metacluster_1/pattern_17

Significance: 0.00045515400000000004

Absent
wES;Hnd_lmb;E11.5;D;En

Pattern: metacluster_0/pattern_22

Significance: 0.016012799999999997

/

Pattern: metacluster_0/pattern_23

Significance: 0.014075999999999998

Absent
memT_tmrD_lstr;TCR_SV40-I_CD8+;D14;A;GEO

Pattern: metacluster_0/pattern_17

Significance: 0.00178523

Absent
memT_tmrD;TCR_SV40-I_CD8+;D14;A;GEO

Pattern: metacluster_1/pattern_16

Significance: 0.00202895

Absent
wES;3rd_Rhmbmr;E8.5;A;GEO

Pattern: metacluster_0/pattern_14

Significance: 0.020679

/

Pattern: metacluster_0/pattern_17

Significance: 0.0381952

Absent
Tfr_mut;CD4+CD44+CXCR5+PD1+CD25+;A;CL

Pattern: metacluster_1/pattern_17

Significance: 0.00178199

Absent
npES;5th_Rhmbmr_delC;E8.5;A;GEO

Pattern: metacluster_1/pattern_8

Significance: 0.0287789

Absent
wES;posterior;1;E9.5;A;GEO

Pattern: metacluster_1/pattern_12

Significance: 0.00332383

Absent
wES;posterior;1;E8.5;A;GEO

Pattern: metacluster_0/pattern_21

Significance: 0.027414499999999998

/

Pattern: metacluster_0/pattern_24

Significance: 0.000764496

Absent
npES;posterior_delA;E8.5;A;GEO

Pattern: metacluster_0/pattern_13

Significance: 0.0389891

Absent
npES;posterior_delC;E8.5;A;GEO

Pattern: metacluster_0/pattern_20

Significance: 0.00142347

/

Pattern: metacluster_0/pattern_21

Significance: 0.0467303

/

Pattern: metacluster_0/pattern_22

Significance: 0.0143561

/

Pattern: metacluster_0/pattern_24

Significance: 0.029586400000000002

Absent
CD4+CD8-TCR+CD25-Foxp3+;A;CL

Pattern: metacluster_1/pattern_23

Significance: 0.00738164

Absent
CD4+CD8-TCR+CD25+Foxp3+;A;CL

Pattern: metacluster_1/pattern_14

Significance: 0.00187003

Absent
SML_INTSTN;A;CL

Pattern: metacluster_0/pattern_3

Significance: 0.0564344

Absent
LRG_INTSTN;A;CL

Pattern: metacluster_0/pattern_1

Significance: 0.050881300000000004

Absent
ThMS_MEC;Aire++;A;GEO

Pattern: metacluster_1/pattern_16

Significance: 0.0254849

Absent
Muscle;A;CL

Pattern: metacluster_1/pattern_21

Significance: 0.000642274

Absent
Melanotrope;A;GEO

Pattern: metacluster_0/pattern_13

Significance: 0.0162363

Absent
Adrenal;A;CL

Pattern: metacluster_1/pattern_0

Significance: 0.05411669999999999

Absent
ES;E14;D;En

Pattern: metacluster_1/pattern_15

Significance: 0.053954300000000004

Absent
ES;C57BL_6J;R1;D;En

Pattern: metacluster_1/pattern_13

Significance: 0.04683180000000001

Absent
KDNY;P0;D;En

Pattern: metacluster_1/pattern_23

Significance: 0.0214039

Absent
wES;LVR;E11.5;D.;En

Pattern: metacluster_1/pattern_15

Significance: 0.0174173

Absent
ES;J1;A;CL

Pattern: metacluster_1/pattern_12

Significance: 0.00849126

Absent
LVR;P0;D;En

Pattern: metacluster_1/pattern_10

Significance: 0.0503598

Absent
ES;129SV_Jae_C57BL6J;A;GEO

Pattern: metacluster_1/pattern_15

Significance: 0.0320177

Absent
Heart;8wks;D;En

Pattern: metacluster_0/pattern_16

Significance: 0.0142391

Absent
Heart;P0;D;En

Pattern: metacluster_1/pattern_19

Significance: 0.0386468

Absent
ILC2+IL33+IL25;A;GEO

Pattern: metacluster_1/pattern_13

Significance: 0.031053700000000004

Absent
T_LCMV;CD8+;D35;A;GEO

Pattern: metacluster_1/pattern_16

Significance: 0.00041971

Absent
Unique Cell types only Homer finds Nr4a2: #2

Cell typeModiscoHomer
DC_BMD;A;CLAbsent

Pattern: motif13.motif

Significance: 0.0152345

ES;ZhBTc4;untreated;A;GEOAbsent

Pattern: motif19.motif

Significance: 0.026808299999999997