In [1]:
# Parameters
data_name = "Nr2c1"
task_idxs = "0-213,216-278"
homer_root = "/srv/scratch/msharmin/mouse_hem/with_tfd/full_mouse50/Naive_scans"
modisco_root = "/srv/scratch/msharmin/mouse_hem/with_tfd/full_mouse50/Naive_modisco2019"
overwrite = False
In [2]:
from matlas.reports import collect_motifDB_to_be_displayed, display_comparative_cell_types

load data from labcluster

Using TensorFlow backend.
2019-08-23 11:25:28,276 [WARNING] git-lfs not installed
In [3]:
homer_matches, modisco_matches = collect_motifDB_to_be_displayed(task_idxs, homer_root, modisco_root, 
                                                              overwrite=False)

TF-MoDISco is using the TensorFlow backend.
In [4]:
display_comparative_cell_types(data_name, homer_matches, modisco_matches)
Nr2c1: Motif: M02399_2.00



Forward PWM

Reverse PWM

Shared Cell types both TF-MoDISco and Homer finds Nr2c1: #14

Cell typeModiscoHomer
wES;5th_Rhmbmr;E8.5;A;GEO

Pattern: metacluster_0/pattern_5

Significance: 0.00563165

Pattern: motif17.motif

Significance: 0.027722000000000004

npES;5th_Rhmbmr_delA;E8.5;A;GEO

Pattern: metacluster_0/pattern_14

Significance: 0.0378903

/

Pattern: metacluster_0/pattern_17

Significance: 0.032108199999999996

Pattern: motif13.motif

Significance: 0.0435385

/

Pattern: motif18.motif

Significance: 0.050027499999999996

wES;posterior;1;E9.5;A;GEO

Pattern: metacluster_1/pattern_12

Significance: 0.00517368

Pattern: motif8.motif

Significance: 0.0582553

wES;posterior;2;E9.5;A;GEO

Pattern: metacluster_0/pattern_8

Significance: 0.00617084

/

Pattern: metacluster_0/pattern_15

Significance: 0.0286616

Pattern: motif9.motif

Significance: 0.0333923

LVR;8wks;D;En

Pattern: metacluster_0/pattern_0

Significance: 0.00462124

Pattern: motif2.motif

Significance: 0.000330375

LRG_INTSTN;8wks;D;En

Pattern: metacluster_1/pattern_2

Significance: 0.016498699999999998

Pattern: motif3.motif

Significance: 0.00639785

Adipocyte_3T3-L1D;C57BL6;D8;D;En

Pattern: metacluster_1/pattern_9

Significance: 0.055358500000000005

Pattern: motif10.motif

Significance: 0.03994330000000001

LVR;8wks;D;GEO

Pattern: metacluster_1/pattern_0

Significance: 0.00257734

Pattern: motif1.motif

Significance: 0.00175503

wES;MSDRM;E11.5;D;En

Pattern: metacluster_0/pattern_11

Significance: 0.021913400000000003

Pattern: motif19.motif

Significance: 0.05950219999999999

placenta;A;CL

Pattern: metacluster_0/pattern_11

Significance: 0.052517799999999996

Pattern: motif12.motif

Significance: 0.00173103

npES;3rd_Rhmbmr_delA;E8.5;A;GEO

Pattern: metacluster_0/pattern_15

Significance: 0.0455279

/

Pattern: metacluster_0/pattern_17

Significance: 0.0316957

Pattern: motif20.motif

Significance: 0.000813956

wES;3rd_Rhmbmr;E8.5;A;GEO

Pattern: metacluster_0/pattern_14

Significance: 0.0468825

/

Pattern: metacluster_0/pattern_17

Significance: 0.046472

Pattern: motif20.motif

Significance: 0.0516384

npES;3rd_Rhmbmr_delC;E8.5;A;GEO

Pattern: metacluster_0/pattern_13

Significance: 0.0542436

/

Pattern: metacluster_0/pattern_16

Significance: 0.0442209

Pattern: motif15.motif

Significance: 0.03524

KDNY;8wks;D;En

Pattern: metacluster_1/pattern_1

Significance: 0.00204697

Pattern: motif2.motif

Significance: 0.00330829

Unique Cell types only TF-MoDISco finds Nr2c1: #23

Cell typeModiscoHomer
T_MLD;TCR_SV40-I_CD8+;D28;A;GEO

Pattern: metacluster_1/pattern_17

Significance: 0.0497493

Absent
wES;Hnd_lmb;E11.5;D;En

Pattern: metacluster_0/pattern_22

Significance: 0.00794168

/

Pattern: metacluster_0/pattern_23

Significance: 0.0348624

Absent
memT_tmrD_lstr;TCR_SV40-I_CD8+;D14;A;GEO

Pattern: metacluster_0/pattern_17

Significance: 0.0547492

Absent
memT_tmrD;TCR_SV40-I_CD8+;D14;A;GEO

Pattern: metacluster_1/pattern_16

Significance: 0.0340649

Absent
Tfr_mut;CD4+CD44+CXCR5+PD1+CD25+;A;CL

Pattern: metacluster_1/pattern_17

Significance: 0.0441314

Absent
wES;posterior;1;E8.5;A;GEO

Pattern: metacluster_0/pattern_21

Significance: 0.00494288

/

Pattern: metacluster_0/pattern_24

Significance: 0.00408212

Absent
npES;posterior_delC;E8.5;A;GEO

Pattern: metacluster_0/pattern_20

Significance: 0.000111141

/

Pattern: metacluster_0/pattern_21

Significance: 0.0340864

/

Pattern: metacluster_0/pattern_22

Significance: 0.010694

Absent
CD4+CD8-TCR+CD25-Foxp3+;A;CL

Pattern: metacluster_1/pattern_23

Significance: 0.036932599999999996

Absent
CD4+CD8-TCR+CD25+Foxp3+;A;CL

Pattern: metacluster_1/pattern_14

Significance: 0.025530200000000003

Absent
SML_INTSTN;A;CL

Pattern: metacluster_0/pattern_3

Significance: 0.0168373

Absent
LRG_INTSTN;A;CL

Pattern: metacluster_0/pattern_1

Significance: 0.0504685

Absent
ThMS_MEC;Aire++;A;GEO

Pattern: metacluster_1/pattern_16

Significance: 0.0198708

Absent
Muscle;A;CL

Pattern: metacluster_1/pattern_21

Significance: 0.0420103

Absent
npES;ZHBTC4;Brg1fl_fl;untreat;A;GEO

Pattern: metacluster_1/pattern_23

Significance: 0.058991499999999995

Absent
ES;E14;D;En

Pattern: metacluster_1/pattern_15

Significance: 0.0283107

Absent
KDNY;P0;D;En

Pattern: metacluster_1/pattern_23

Significance: 0.0270548

Absent
wES;LVR;E11.5;D.;En

Pattern: metacluster_1/pattern_15

Significance: 0.012175700000000001

Absent
ES;J1;A;CL

Pattern: metacluster_1/pattern_12

Significance: 0.0402121

Absent
LVR;P0;D;En

Pattern: metacluster_1/pattern_10

Significance: 0.00386846

Absent
ES;129SV_Jae_C57BL6J;A;GEO

Pattern: metacluster_1/pattern_15

Significance: 0.0249739

Absent
Heart;8wks;D;En

Pattern: metacluster_0/pattern_16

Significance: 0.04919

Absent
Heart;P0;D;En

Pattern: metacluster_1/pattern_19

Significance: 0.05511459999999999

Absent
T_LCMV;CD8+;D35;A;GEO

Pattern: metacluster_1/pattern_16

Significance: 0.0499487

Absent
Unique Cell types only Homer finds Nr2c1: #5

Cell typeModiscoHomer
ES;v6.5;A;GEOAbsent

Pattern: motif19.motif

Significance: 0.036617800000000006

ES;ZhBTc4;2;D;GEOAbsent

Pattern: motif12.motif

Significance: 0.0391728

DC_BMD;A;CLAbsent

Pattern: motif13.motif

Significance: 0.026607799999999997

npES;ZHBTC4;doxyc;treat;A;GEOAbsent

Pattern: motif14.motif

Significance: 0.0293774

wES;5th_Rhmbmr;E9.5;A;GEOAbsent

Pattern: motif9.motif

Significance: 0.05306469999999999