In [1]:
# Parameters
data_name = "Twist1"
task_idxs = "0-213,216-278"
homer_root = "/srv/scratch/msharmin/mouse_hem/with_tfd/full_mouse50/Naive_scans"
modisco_root = "/srv/scratch/msharmin/mouse_hem/with_tfd/full_mouse50/Naive_modisco2019"
overwrite = False
In [2]:
from matlas.reports import collect_motifDB_to_be_displayed, display_comparative_cell_types

load data from labcluster

Using TensorFlow backend.
2019-08-23 11:46:31,301 [WARNING] git-lfs not installed
In [3]:
homer_matches, modisco_matches = collect_motifDB_to_be_displayed(task_idxs, homer_root, modisco_root, 
                                                              overwrite=False)

TF-MoDISco is using the TensorFlow backend.
In [4]:
display_comparative_cell_types(data_name, homer_matches, modisco_matches)
Twist1: Motif: M08766_2.00



Forward PWM

Reverse PWM

Shared Cell types both TF-MoDISco and Homer finds Twist1: #17

Cell typeModiscoHomer
wES;limb;E14.5;D;En

Pattern: metacluster_1/pattern_1

Significance: 2.0155599999999998e-18

Pattern: motif5.motif

Significance: 0.00730577

wES;limb;E11.5;D;En

Pattern: metacluster_0/pattern_6

Significance: 8.3018e-05

/

Pattern: metacluster_0/pattern_7

Significance: 4.45452e-19

Pattern: motif4.motif

Significance: 0.00016136

/

Pattern: motif12.motif

Significance: 0.000388593

wES;Fr_lmb;E11.5;D;En

Pattern: metacluster_1/pattern_3

Significance: 1.23435e-07

/

Pattern: metacluster_1/pattern_6

Significance: 1.40126e-17

Pattern: motif5.motif

Significance: 9.042229999999999e-05

/

Pattern: motif6.motif

Significance: 0.0222502

wES;Hnd_lmb;E11.5;D;En

Pattern: metacluster_0/pattern_2

Significance: 5.88523e-18

/

Pattern: metacluster_0/pattern_3

Significance: 0.0425793

Pattern: motif3.motif

Significance: 0.00016051799999999998

/

Pattern: motif11.motif

Significance: 0.0007053560000000001

LNG;P0;D;En

Pattern: metacluster_1/pattern_11

Significance: 0.00501808

Pattern: motif18.motif

Significance: 0.033139

wES;LNG;E14.5;D;En

Pattern: metacluster_1/pattern_6

Significance: 0.00472124

Pattern: motif13.motif

Significance: 0.0164539

wES;FaceP;E14.5;D;En

Pattern: metacluster_0/pattern_1

Significance: 6.97427e-08

/

Pattern: metacluster_0/pattern_7

Significance: 0.032775599999999995

/

Pattern: metacluster_0/pattern_8

Significance: 3.9213499999999997e-13

Pattern: motif5.motif

Significance: 0.00316468

wES;FaceP;E11.5;D;En

Pattern: metacluster_1/pattern_2

Significance: 9.61692e-18

/

Pattern: metacluster_1/pattern_4

Significance: 2.39586e-13

Pattern: motif3.motif

Significance: 4.61911e-08

/

Pattern: motif7.motif

Significance: 0.0005305490000000001

wES;NRL_Tube;E11.5;D;En

Pattern: metacluster_1/pattern_5

Significance: 0.00599965

Pattern: motif15.motif

Significance: 0.028370299999999998

CRBL_GRNL_Precrsr;A;GEO

Pattern: metacluster_0/pattern_0

Significance: 0.0505661

/

Pattern: metacluster_0/pattern_6

Significance: 0.019024

Pattern: motif2.motif

Significance: 0.0273952

wES.CRNL_NRL_CRST;E10.5;A;GEO

Pattern: metacluster_0/pattern_5

Significance: 4.7348e-14

/

Pattern: metacluster_0/pattern_7

Significance: 0.0228078

Pattern: motif3.motif

Significance: 0.00553084

/

Pattern: motif13.motif

Significance: 0.0356778

RTN;D1;D;En

Pattern: metacluster_0/pattern_3

Significance: 0.05111280000000001

/

Pattern: metacluster_0/pattern_4

Significance: 0.0540564

Pattern: motif16.motif

Significance: 0.0535591

eCortical_NRN;A;GEO

Pattern: metacluster_1/pattern_3

Significance: 0.0431375

Pattern: motif4.motif

Significance: 0.040052

wES;MSDRM;E11.5;D;En

Pattern: metacluster_0/pattern_1

Significance: 9.38297e-05

/

Pattern: metacluster_0/pattern_5

Significance: 0.0577434

Pattern: motif4.motif

Significance: 0.020804800000000002

wES;WHL_BRN;E14.5;D;GEO

Pattern: metacluster_0/pattern_0

Significance: 0.058830999999999994

Pattern: motif13.motif

Significance: 0.0461893

3T3-L1;D;En

Pattern: metacluster_1/pattern_12

Significance: 1.90716e-17

Pattern: motif15.motif

Significance: 0.0345231

KDNY;P0;D;En

Pattern: metacluster_1/pattern_9

Significance: 0.00022769

Pattern: motif15.motif

Significance: 0.039407

Unique Cell types only TF-MoDISco finds Twist1: #45

Cell typeModiscoHomer
proB;A;CL

Pattern: metacluster_1/pattern_3

Significance: 0.05686889999999999

Absent
prePLSM_B;A;GEO

Pattern: metacluster_1/pattern_20

Significance: 0.0241417

Absent
plasmaB;A;CL

Pattern: metacluster_1/pattern_5

Significance: 0.0381466

Absent
MCRPHG_BMD.UnStmltd;A;GEO

Pattern: metacluster_1/pattern_11

Significance: 0.0592695

Absent
NIH3T3;D;En

Pattern: metacluster_1/pattern_8

Significance: 1.17009e-19

Absent
MTR_NRN_MN1;methyl3;D;En

Pattern: metacluster_0/pattern_12

Significance: 0.0462225

/

Pattern: metacluster_0/pattern_15

Significance: 0.056114699999999997

Absent
npES;3rd_Rhmbmr_delA;E8.5;A;GEO

Pattern: metacluster_0/pattern_16

Significance: 0.059417099999999994

Absent
wES;3rd_Rhmbmr;E8.5;A;GEO

Pattern: metacluster_0/pattern_10

Significance: 0.00808613

/

Pattern: metacluster_0/pattern_21

Significance: 0.00117921

/

Pattern: metacluster_0/pattern_22

Significance: 2.27607e-14

Absent
npES;3rd_Rhmbmr_delC;E8.5;A;GEO

Pattern: metacluster_0/pattern_14

Significance: 0.00107841

/

Pattern: metacluster_0/pattern_20

Significance: 6.01437e-07

Absent
npES;5th_Rhmbmr_delC;E8.5;A;GEO

Pattern: metacluster_1/pattern_23

Significance: 2.22915e-11

Absent
wES;5th_Rhmbmr;E9.5;A;GEO

Pattern: metacluster_0/pattern_15

Significance: 0.035518400000000006

/

Pattern: metacluster_0/pattern_21

Significance: 0.000101261

/

Pattern: metacluster_0/pattern_22

Significance: 0.00879633

/

Pattern: metacluster_0/pattern_24

Significance: 8.885210000000001e-10

Absent
wES;5th_Rhmbmr;E8.5;A;GEO

Pattern: metacluster_0/pattern_12

Significance: 0.00705909

/

Pattern: metacluster_0/pattern_22

Significance: 1.91213e-11

/

Pattern: metacluster_0/pattern_25

Significance: 0.013960399999999998

/

Pattern: metacluster_0/pattern_28

Significance: 0.023191999999999997

Absent
npES;5th_Rhmbmr_delA;E8.5;A;GEO

Pattern: metacluster_0/pattern_5

Significance: 0.0564985

/

Pattern: metacluster_0/pattern_20

Significance: 0.00837683

Absent
wES;posterior;1;E9.5;A;GEO

Pattern: metacluster_1/pattern_5

Significance: 0.000141998

Absent
wES;posterior;2;E9.5;A;GEO

Pattern: metacluster_0/pattern_9

Significance: 0.00117585

/

Pattern: metacluster_0/pattern_21

Significance: 1.6215e-07

Absent
wES;posterior;1;E8.5;A;GEO

Pattern: metacluster_0/pattern_10

Significance: 0.00545791

/

Pattern: metacluster_0/pattern_18

Significance: 0.00111408

Absent
npES;posterior_delA;E8.5;A;GEO

Pattern: metacluster_0/pattern_8

Significance: 0.00013022

Absent
npES;posterior_delC;E8.5;A;GEO

Pattern: metacluster_0/pattern_9

Significance: 0.00039116199999999997

Absent
BCK_SKN;A;GEO

Pattern: metacluster_0/pattern_6

Significance: 0.057437

Absent
iVIP_NRN;A;GEO

Pattern: metacluster_1/pattern_0

Significance: 0.022297099999999997

Absent
G_NRN_P;A;GEO

Pattern: metacluster_1/pattern_0

Significance: 0.055184199999999996

/

Pattern: metacluster_1/pattern_14

Significance: 0.0145987

Absent
ES;MEF;A;CL

Pattern: metacluster_1/pattern_16

Significance: 1.43353e-17

Absent
LNG;A;CL

Pattern: metacluster_1/pattern_20

Significance: 0.0258278

Absent
Heart;D;En

Pattern: metacluster_0/pattern_8

Significance: 0.00723974

Absent
pMeg;A;En

Pattern: metacluster_1/pattern_6

Significance: 0.05985309999999999

Absent
BRN;FRNTL_CRTX;A;CL

Pattern: metacluster_1/pattern_12

Significance: 0.031653

Absent
BRN;SNSR_MTR_CRTX;A;CL

Pattern: metacluster_1/pattern_6

Significance: 0.021000799999999997

Absent
NIH3T3_FBROBLST;D;GEO

Pattern: metacluster_1/pattern_9

Significance: 1.7452300000000002e-23

Absent
LNG;8wks;D;GEO

Pattern: metacluster_0/pattern_21

Significance: 0.00836789

Absent
WHL_BRN;8wks;D;GEO

Pattern: metacluster_1/pattern_2

Significance: 0.05159009999999999

/

Pattern: metacluster_1/pattern_10

Significance: 0.0438213

Absent
NIH3T3_FBROBLST;D;En

Pattern: metacluster_1/pattern_8

Significance: 5.998880000000001e-22

Absent
FBRBLST;8wks;D;En

Pattern: metacluster_1/pattern_15

Significance: 4.9860599999999995e-19

Absent
3T3-L1;FBRBLST;D;En

Pattern: metacluster_1/pattern_14

Significance: 6.541419999999999e-18

Absent
LNG;8wks;D;En

Pattern: metacluster_0/pattern_17

Significance: 0.00128509

Absent
Heart;8wks;D;En

Pattern: metacluster_0/pattern_11

Significance: 0.0183927

Absent
Adipocyte_3T3-L1D;C57BL6;D8;D;En

Pattern: metacluster_1/pattern_16

Significance: 3.51179e-19

Absent
wES;RTN;E11.5;D;En

Pattern: metacluster_0/pattern_1

Significance: 0.028504200000000004

/

Pattern: metacluster_0/pattern_3

Significance: 0.042715699999999995

Absent
Muller;P12;D;En

Pattern: metacluster_1/pattern_5

Significance: 0.056050499999999996

Absent
wES.Fr_BRN;E14.4;D;En

Pattern: metacluster_0/pattern_2

Significance: 0.0568052

Absent
Fr_BRN;P0;D;En

Pattern: metacluster_1/pattern_4

Significance: 0.052090599999999994

/

Pattern: metacluster_1/pattern_10

Significance: 0.054692

/

Pattern: metacluster_1/pattern_15

Significance: 0.0264842

Absent
wES;Hnd_BRN;E11.5;D;En

Pattern: metacluster_0/pattern_4

Significance: 0.00497956

Absent
wES;Hnd_BRN;E14.5;D;En

Pattern: metacluster_0/pattern_8

Significance: 0.0326978

Absent
wES;Md_BRN;E14.4;D;En

Pattern: metacluster_0/pattern_6

Significance: 0.0385351

Absent
Md_BRN;D;En

Pattern: metacluster_1/pattern_3

Significance: 0.018080099999999998

Absent
wES;Telenchephalon;D;En

Pattern: metacluster_1/pattern_3

Significance: 0.0393204

Absent
Unique Cell types only Homer finds Twist1: #2

Cell typeModiscoHomer
B;B220_CD43;A;GEOAbsent

Pattern: motif11.motif

Significance: 0.0485336

ePyramidal_NRN;A;GEOAbsent

Pattern: motif4.motif

Significance: 0.00878299