In [1]:
# Parameters
data_name = "Nr2f1"
task_idxs = "0-213,216-278"
homer_root = "/srv/scratch/msharmin/mouse_hem/with_tfd/full_mouse50/Naive_scans"
modisco_root = "/srv/scratch/msharmin/mouse_hem/with_tfd/full_mouse50/Naive_modisco2019"
overwrite = False
In [2]:
from matlas.reports import collect_motifDB_to_be_displayed, display_comparative_cell_types

load data from labcluster

Using TensorFlow backend.
2019-08-23 11:25:36,514 [WARNING] git-lfs not installed
In [3]:
homer_matches, modisco_matches = collect_motifDB_to_be_displayed(task_idxs, homer_root, modisco_root, 
                                                              overwrite=False)

TF-MoDISco is using the TensorFlow backend.
In [4]:
display_comparative_cell_types(data_name, homer_matches, modisco_matches)
Nr2f1: Motif: M00822_2.00



Forward PWM

Reverse PWM

Shared Cell types both TF-MoDISco and Homer finds Nr2f1: #18

Cell typeModiscoHomer
wES;5th_Rhmbmr;E8.5;A;GEO

Pattern: metacluster_0/pattern_5

Significance: 0.0066077

Pattern: motif11.motif

Significance: 0.05044

/

Pattern: motif17.motif

Significance: 0.030675599999999997

npES;5th_Rhmbmr_delA;E8.5;A;GEO

Pattern: metacluster_0/pattern_14

Significance: 0.0516151

/

Pattern: metacluster_0/pattern_17

Significance: 0.00011116799999999999

Pattern: motif18.motif

Significance: 3.66729e-05

wES;posterior;1;E9.5;A;GEO

Pattern: metacluster_1/pattern_12

Significance: 0.00573574

Pattern: motif8.motif

Significance: 0.0582553

wES;posterior;2;E9.5;A;GEO

Pattern: metacluster_0/pattern_8

Significance: 0.00865584

/

Pattern: metacluster_0/pattern_15

Significance: 0.000225089

Pattern: motif9.motif

Significance: 0.0366152

LVR;8wks;D;En

Pattern: metacluster_0/pattern_0

Significance: 1.91669e-05

Pattern: motif2.motif

Significance: 2.46488e-05

LRG_INTSTN;8wks;D;En

Pattern: metacluster_1/pattern_2

Significance: 0.000736256

Pattern: motif3.motif

Significance: 0.00200131

ES;D0;D;GEO

Pattern: metacluster_0/pattern_10

Significance: 0.0440455

Pattern: motif14.motif

Significance: 0.04648719999999999

Adipocyte_3T3-L1D;C57BL6;D8;D;En

Pattern: metacluster_1/pattern_9

Significance: 2.5738900000000003e-07

Pattern: motif10.motif

Significance: 2.57663e-07

LVR;8wks;D;GEO

Pattern: metacluster_1/pattern_0

Significance: 1.53308e-05

Pattern: motif1.motif

Significance: 9.68532e-05

placenta;A;CL

Pattern: metacluster_0/pattern_11

Significance: 3.49718e-06

Pattern: motif12.motif

Significance: 5.6007799999999996e-05

SML_INTSTN;A;CL

Pattern: metacluster_0/pattern_3

Significance: 0.0007364439999999999

Pattern: motif5.motif

Significance: 0.0208642

LRG_INTSTN;A;CL

Pattern: metacluster_0/pattern_1

Significance: 0.00247447

Pattern: motif2.motif

Significance: 0.033912199999999997

wES;MSDRM;E11.5;D;En

Pattern: metacluster_0/pattern_11

Significance: 0.0567341

Pattern: motif14.motif

Significance: 0.057638199999999994

/

Pattern: motif19.motif

Significance: 8.49684e-05

npES;ZHBTC4;doxyc;treat;A;GEO

Pattern: metacluster_0/pattern_13

Significance: 0.0502091

Pattern: motif14.motif

Significance: 0.026618799999999998

npES;ZHBTC4;Brg1fl_fl;untreat;A;GEO

Pattern: metacluster_1/pattern_23

Significance: 0.059992899999999995

Pattern: motif32.motif

Significance: 0.029148700000000003

npES;3rd_Rhmbmr_delA;E8.5;A;GEO

Pattern: metacluster_0/pattern_15

Significance: 0.0194509

/

Pattern: metacluster_0/pattern_17

Significance: 0.000203721

Pattern: motif20.motif

Significance: 4.85399e-05

npES;3rd_Rhmbmr_delC;E8.5;A;GEO

Pattern: metacluster_0/pattern_13

Significance: 0.032228700000000006

/

Pattern: metacluster_0/pattern_16

Significance: 2.07775e-05

Pattern: motif15.motif

Significance: 0.03524

KDNY;8wks;D;En

Pattern: metacluster_1/pattern_1

Significance: 2.1252600000000004e-05

Pattern: motif2.motif

Significance: 0.00018245900000000002

Unique Cell types only TF-MoDISco finds Nr2f1: #27

Cell typeModiscoHomer
T_MLD;TCR_SV40-I_CD8+;D28;A;GEO

Pattern: metacluster_1/pattern_17

Significance: 0.000635437

Absent
wES;Hnd_lmb;E11.5;D;En

Pattern: metacluster_0/pattern_22

Significance: 0.0261276

/

Pattern: metacluster_0/pattern_23

Significance: 2.1715500000000002e-05

Absent
memT_tmrD_lstr;TCR_SV40-I_CD8+;D14;A;GEO

Pattern: metacluster_0/pattern_17

Significance: 0.025642200000000004

Absent
memT_tmrD;TCR_SV40-I_CD8+;D14;A;GEO

Pattern: metacluster_1/pattern_16

Significance: 0.058513800000000005

Absent
STMCH;P0;D;En

Pattern: metacluster_1/pattern_11

Significance: 0.0159485

Absent
wES;3rd_Rhmbmr;E8.5;A;GEO

Pattern: metacluster_0/pattern_14

Significance: 0.053231600000000004

/

Pattern: metacluster_0/pattern_17

Significance: 0.000861498

Absent
Tfr_mut;CD4+CD44+CXCR5+PD1+CD25+;A;CL

Pattern: metacluster_1/pattern_17

Significance: 0.037069599999999994

Absent
npES;5th_Rhmbmr_delC;E8.5;A;GEO

Pattern: metacluster_1/pattern_8

Significance: 0.03642

Absent
wES;posterior;1;E8.5;A;GEO

Pattern: metacluster_0/pattern_21

Significance: 0.0208419

/

Pattern: metacluster_0/pattern_24

Significance: 3.81924e-05

Absent
npES;posterior_delA;E8.5;A;GEO

Pattern: metacluster_0/pattern_13

Significance: 0.04924269999999999

Absent
npES;posterior_delC;E8.5;A;GEO

Pattern: metacluster_0/pattern_20

Significance: 4.04955e-05

/

Pattern: metacluster_0/pattern_21

Significance: 0.00178441

/

Pattern: metacluster_0/pattern_22

Significance: 0.0120389

/

Pattern: metacluster_0/pattern_24

Significance: 0.0356856

Absent
CD4+CD8-TCR+CD25-Foxp3+;A;CL

Pattern: metacluster_1/pattern_23

Significance: 0.0032435000000000003

Absent
CD4+CD8-TCR+CD25+Foxp3+;A;CL

Pattern: metacluster_1/pattern_14

Significance: 0.0520505

Absent
ThMS_MEC;Aire++;A;GEO

Pattern: metacluster_1/pattern_16

Significance: 0.00237246

Absent
Muscle;A;CL

Pattern: metacluster_1/pattern_21

Significance: 0.000534618

Absent
Adrenal;A;CL

Pattern: metacluster_1/pattern_0

Significance: 0.0368734

/

Pattern: metacluster_1/pattern_15

Significance: 0.054765499999999995

Absent
pCMP;A;CL

Pattern: metacluster_1/pattern_16

Significance: 0.054515999999999995

Absent
KDNY;P0;D;En

Pattern: metacluster_1/pattern_23

Significance: 0.00159204

Absent
wES;LVR;E11.5;D.;En

Pattern: metacluster_1/pattern_15

Significance: 1.4976199999999999e-05

Absent
ES;J1;A;CL

Pattern: metacluster_1/pattern_12

Significance: 0.05152230000000001

Absent
ES;E14;A;GEO

Pattern: metacluster_0/pattern_18

Significance: 0.0546383

Absent
LVR;P0;D;En

Pattern: metacluster_1/pattern_10

Significance: 0.000627175

Absent
Heart;8wks;D;En

Pattern: metacluster_0/pattern_16

Significance: 0.015126599999999999

Absent
Heart;P0;D;En

Pattern: metacluster_1/pattern_19

Significance: 0.0386468

Absent
ILC2+IL33+IL25;A;GEO

Pattern: metacluster_1/pattern_13

Significance: 0.057447000000000005

Absent
T_LCMV;CD8+;D35;A;GEO

Pattern: metacluster_1/pattern_16

Significance: 0.0005813319999999999

Absent
naiveT;trnsgncTCR_SV40-I_CD8;A;GEO

Pattern: metacluster_0/pattern_10

Significance: 0.056688199999999994

Absent
Unique Cell types only Homer finds Nr2f1: #8

Cell typeModiscoHomer
LNG;8wks;D;EnAbsent

Pattern: motif8.motif

Significance: 0.0523127

ES;ZhBTc4;1;D;GEOAbsent

Pattern: motif14.motif

Significance: 0.0200965

ES;ZhBTc4;2;D;GEOAbsent

Pattern: motif12.motif

Significance: 0.0465482

DC_BMD;A;CLAbsent

Pattern: motif13.motif

Significance: 0.029620999999999998

ROD_PHT_RCPTR;A;GEOAbsent

Pattern: motif9.motif

Significance: 0.0599058

ES;ZhBTc4;untreated;A;GEOAbsent

Pattern: motif19.motif

Significance: 0.026808299999999997

ES;129S1_SVImJ_CJ7;D;EnAbsent

Pattern: motif18.motif

Significance: 0.0491168

wES;5th_Rhmbmr;E9.5;A;GEOAbsent

Pattern: motif9.motif

Significance: 0.048542699999999994