In [1]:
# Parameters
data_name = "Nfatc1"
task_idxs = "0-213,216-278"
homer_root = "/srv/scratch/msharmin/mouse_hem/with_tfd/full_mouse50/Naive_scans"
modisco_root = "/srv/scratch/msharmin/mouse_hem/with_tfd/full_mouse50/Naive_modisco2019"
overwrite = False
In [2]:
from matlas.reports import collect_motifDB_to_be_displayed, display_comparative_cell_types

load data from labcluster

Using TensorFlow backend.
2019-08-23 11:22:19,496 [WARNING] git-lfs not installed
In [3]:
homer_matches, modisco_matches = collect_motifDB_to_be_displayed(task_idxs, homer_root, modisco_root, 
                                                              overwrite=False)

TF-MoDISco is using the TensorFlow backend.
In [4]:
display_comparative_cell_types(data_name, homer_matches, modisco_matches)
Nfatc1: Motif: M09360_2.00



Forward PWM

Reverse PWM

Shared Cell types both TF-MoDISco and Homer finds Nfatc1: #3

Cell typeModiscoHomer
Th17;CD4+;A;CL

Pattern: metacluster_1/pattern_6

Significance: 0.030676599999999995

Pattern: motif16.motif

Significance: 0.00316063

Tfr;CD4+CD44+CXCR5+PD1+CD25+;A;CL

Pattern: metacluster_1/pattern_13

Significance: 0.012790799999999998

Pattern: motif17.motif

Significance: 0.0433963

wCH12_drug;A;CL

Pattern: metacluster_1/pattern_16

Significance: 0.0210784

Pattern: motif19.motif

Significance: 0.050415499999999995

Unique Cell types only TF-MoDISco finds Nfatc1: #25

Cell typeModiscoHomer
memT_tmrD_lstr;TCR_SV40-I_CD8+;D7;A;GEO

Pattern: metacluster_1/pattern_13

Significance: 0.00547504

Absent
memT_tmrD_lstr;TCR_SV40-I_CD8+;D14;A;GEO

Pattern: metacluster_0/pattern_16

Significance: 7.11725e-05

Absent
memT_tmrD;TCR_SV40-I_CD8+;D7;A;GEO

Pattern: metacluster_1/pattern_8

Significance: 0.0165852

Absent
416B;HMTP_SPNSN;CD34+;D;En

Pattern: metacluster_1/pattern_13

Significance: 0.0121479

Absent
B;B220_CD43;A;GEO

Pattern: metacluster_1/pattern_28

Significance: 0.0116774

Absent
DC_LPS;2h;A;GEO

Pattern: metacluster_1/pattern_16

Significance: 0.0423662

Absent
ENDRM_ESD;A;GEO

Pattern: metacluster_1/pattern_14

Significance: 0.0194678

Absent
Tfh;A;CL

Pattern: metacluster_1/pattern_15

Significance: 0.0219297

Absent
Tfh_mut;A;CL

Pattern: metacluster_1/pattern_7

Significance: 0.00055478

Absent
NPC;G4;A;GEO

Pattern: metacluster_1/pattern_15

Significance: 0.033191000000000005

Absent
MCRPHG;A;CL

Pattern: metacluster_1/pattern_13

Significance: 0.042746

Absent
iPV_NRN;A;GEO

Pattern: metacluster_1/pattern_5

Significance: 0.047738199999999995

Absent
pMeg;A;En

Pattern: metacluster_1/pattern_16

Significance: 0.0280117

/

Pattern: metacluster_1/pattern_20

Significance: 0.0228452

Absent
DC_LPS;4h;A;En

Pattern: metacluster_1/pattern_7

Significance: 0.05954109999999999

Absent
ILC2precrsr;A;CL

Pattern: metacluster_1/pattern_18

Significance: 0.0455048

Absent
apTreg;D;GEO

Pattern: metacluster_1/pattern_4

Significance: 0.051769

Absent
aB_LPS+IL4+Oligomycin_24h;A;CL

Pattern: metacluster_1/pattern_5

Significance: 0.047808300000000005

Absent
FBRBLST;8wks;D;En

Pattern: metacluster_1/pattern_21

Significance: 0.0567519

Absent
ES;E14;A;GEO

Pattern: metacluster_0/pattern_12

Significance: 0.0465259

Absent
ES;F1216;A;GEO

Pattern: metacluster_0/pattern_11

Significance: 0.0394626

Absent
ES;v6.5;A;GEO

Pattern: metacluster_1/pattern_5

Significance: 0.027247399999999998

Absent
ILC2_AbxGRMFree;A;GEO

Pattern: metacluster_1/pattern_8

Significance: 0.054228399999999996

Absent
416B_MP;CD34+;D;En

Pattern: metacluster_1/pattern_14

Significance: 0.04277569999999999

Absent
TExh_SPLND;CD8+;A;GEO

Pattern: metacluster_1/pattern_17

Significance: 0.0376661

Absent
T_MLD;TCR_SV40-I_CD8+;D5;A;GEO

Pattern: metacluster_1/pattern_10

Significance: 0.00261318

Absent
Unique Cell types only Homer finds Nfatc1: #5

Cell typeModiscoHomer
Mammary_GLND;A;GEOAbsent

Pattern: motif1.motif

Significance: 0.054676800000000005

BCK_SKN;A;GEOAbsent

Pattern: motif4.motif

Significance: 0.053963599999999994

T_SPLND_blstCLTRD;CD4+;D;GEOAbsent

Pattern: motif14.motif

Significance: 0.053394500000000004

NK;IL2+IL12+;A;CLAbsent

Pattern: motif6.motif

Significance: 0.0316884

TSLEC_SPLND;CD8+A;GEOAbsent

Pattern: motif22.motif

Significance: 0.0497699