In [1]:
# Parameters
data_name = "Hoxa2"
task_idxs = "0-213,216-278"
homer_root = "/srv/scratch/msharmin/mouse_hem/with_tfd/full_mouse50/Naive_scans"
modisco_root = "/srv/scratch/msharmin/mouse_hem/with_tfd/full_mouse50/Naive_modisco2019"
overwrite = False
In [2]:
from matlas.reports import collect_motifDB_to_be_displayed, display_comparative_cell_types

load data from labcluster

Using TensorFlow backend.
2019-08-23 11:12:11,254 [WARNING] git-lfs not installed
In [3]:
homer_matches, modisco_matches = collect_motifDB_to_be_displayed(task_idxs, homer_root, modisco_root, 
                                                              overwrite=False)

TF-MoDISco is using the TensorFlow backend.
In [4]:
display_comparative_cell_types(data_name, homer_matches, modisco_matches)
Hoxa2: Motif: M09566_2.00



Forward PWM

Reverse PWM

Shared Cell types both TF-MoDISco and Homer finds Hoxa2: #28

Cell typeModiscoHomer
wES;limb;E11.5;D;En

Pattern: metacluster_0/pattern_3

Significance: 0.00103406

/

Pattern: metacluster_0/pattern_5

Significance: 0.023523699999999998

Pattern: motif4.motif

Significance: 0.0373674

/

Pattern: motif8.motif

Significance: 0.0346987

wES;Hnd_lmb;E11.5;D;En

Pattern: metacluster_0/pattern_1

Significance: 0.00885692

/

Pattern: metacluster_0/pattern_3

Significance: 0.000302751

Pattern: motif3.motif

Significance: 0.044849400000000005

wES;FaceP;E14.5;D;En

Pattern: metacluster_0/pattern_7

Significance: 0.0324214

Pattern: motif14.motif

Significance: 0.0578678

BL_CN_PHT_RCPTR;A;GEO

Pattern: metacluster_1/pattern_18

Significance: 0.021761900000000004

Pattern: motif13.motif

Significance: 0.0129012

wES;3rd_Rhmbmr;E8.5;A;GEO

Pattern: metacluster_0/pattern_21

Significance: 0.0594183

Pattern: motif16.motif

Significance: 0.0150715

wES;5th_Rhmbmr;E8.5;A;GEO

Pattern: metacluster_0/pattern_9

Significance: 8.87115e-06

/

Pattern: metacluster_0/pattern_25

Significance: 0.00751961

Pattern: motif4.motif

Significance: 0.00239477

npES;5th_Rhmbmr_delA;E8.5;A;GEO

Pattern: metacluster_0/pattern_11

Significance: 7.76169e-07

/

Pattern: metacluster_0/pattern_20

Significance: 0.0291515

Pattern: motif20.motif

Significance: 0.030394

wES;posterior;1;E8.5;A;GEO

Pattern: metacluster_0/pattern_11

Significance: 6.76119e-05

/

Pattern: metacluster_0/pattern_18

Significance: 0.00350555

Pattern: motif6.motif

Significance: 3.25814e-06

npES;posterior_delA;E8.5;A;GEO

Pattern: metacluster_0/pattern_5

Significance: 1.01814e-05

/

Pattern: metacluster_0/pattern_6

Significance: 0.053237400000000004

Pattern: motif5.motif

Significance: 5.27217e-05

npES;posterior_delC;E8.5;A;GEO

Pattern: metacluster_0/pattern_6

Significance: 0.0455219

/

Pattern: metacluster_0/pattern_7

Significance: 0.000324343

Pattern: motif7.motif

Significance: 0.00366646

BCK_SKN;A;GEO

Pattern: metacluster_0/pattern_6

Significance: 0.00578856

Pattern: motif9.motif

Significance: 0.00928262

NPC;F129;A;GEO

Pattern: metacluster_1/pattern_16

Significance: 0.047054

Pattern: motif7.motif

Significance: 0.0580236

iVIP_NRN;A;GEO

Pattern: metacluster_1/pattern_6

Significance: 0.038720300000000006

Pattern: motif3.motif

Significance: 0.020620199999999998

G_NRN_P;A;GEO

Pattern: metacluster_1/pattern_14

Significance: 0.00442032

Pattern: motif13.motif

Significance: 0.016236700000000003

ThMS_MEC;Aire++;A;GEO

Pattern: metacluster_1/pattern_13

Significance: 0.0036038000000000003

Pattern: motif15.motif

Significance: 0.00983139

wES;WHL_BRN;E14.5;D;GEO

Pattern: metacluster_0/pattern_0

Significance: 0.00342094

Pattern: motif2.motif

Significance: 0.00571133

KDNY;P0;D;En

Pattern: metacluster_1/pattern_3

Significance: 0.027190499999999996

Pattern: motif4.motif

Significance: 0.0358894

CRBL_GRNL_Precrsr;A;GEO

Pattern: metacluster_0/pattern_6

Significance: 0.00730664

Pattern: motif6.motif

Significance: 0.017838200000000002

RTN;D1;D;En

Pattern: metacluster_0/pattern_3

Significance: 0.00272056

Pattern: motif2.motif

Significance: 0.00545761

wES;RTN;E11.5;D;En

Pattern: metacluster_0/pattern_1

Significance: 0.00242006

Pattern: motif3.motif

Significance: 0.00585722

wES;MSDRM;E11.5;D;En

Pattern: metacluster_0/pattern_0

Significance: 0.013307

/

Pattern: metacluster_0/pattern_5

Significance: 0.0535627

Pattern: motif2.motif

Significance: 0.000220841

Muller;P12;D;En

Pattern: metacluster_1/pattern_5

Significance: 0.00401703

Pattern: motif4.motif

Significance: 0.010807899999999999

wES.Fr_BRN;E14.4;D;En

Pattern: metacluster_0/pattern_2

Significance: 0.0038116

Pattern: motif2.motif

Significance: 0.00482473

Fr_BRN;P0;D;En

Pattern: metacluster_1/pattern_10

Significance: 0.0286139

Pattern: motif10.motif

Significance: 0.0165168

wES;Hnd_BRN;E14.5;D;En

Pattern: metacluster_0/pattern_8

Significance: 0.00784446

Pattern: motif3.motif

Significance: 0.018954

wES;Md_BRN;E14.4;D;En

Pattern: metacluster_0/pattern_6

Significance: 0.005486199999999999

Pattern: motif6.motif

Significance: 0.0172428

Md_BRN;D;En

Pattern: metacluster_1/pattern_3

Significance: 0.013717700000000003

Pattern: motif14.motif

Significance: 0.012265

wES;WHL_BRN;E14.5;D;En

Pattern: metacluster_1/pattern_0

Significance: 0.00290756

Pattern: motif2.motif

Significance: 0.00621698

Unique Cell types only TF-MoDISco finds Hoxa2: #19

Cell typeModiscoHomer
MPP;A;CL

Pattern: metacluster_1/pattern_21

Significance: 0.00185469

Absent
wES;Fr_lmb;E11.5;D;En

Pattern: metacluster_1/pattern_4

Significance: 0.0178847

/

Pattern: metacluster_1/pattern_13

Significance: 0.000917315

Absent
wES;posterior;1;E9.5;A;GEO

Pattern: metacluster_1/pattern_9

Significance: 0.00145106

Absent
KDNY;8wks;D;En

Pattern: metacluster_1/pattern_19

Significance: 0.024327200000000004

Absent
wES;NRL_Tube;E11.5;D;En

Pattern: metacluster_1/pattern_4

Significance: 0.00366935

Absent
Adipose;D;En

Pattern: metacluster_0/pattern_22

Significance: 0.0159639

Absent
NPC;G4;A;GEO

Pattern: metacluster_1/pattern_18

Significance: 0.0452283

Absent
LNG_TRM_HSC;A;CL

Pattern: metacluster_1/pattern_20

Significance: 0.010979299999999999

Absent
NPC;mE6;A;GEO

Pattern: metacluster_1/pattern_9

Significance: 0.055491

Absent
AML;D;En

Pattern: metacluster_1/pattern_18

Significance: 0.030783799999999997

Absent
iPV_NRN;A;GEO

Pattern: metacluster_1/pattern_7

Significance: 0.014942400000000002

Absent
NIH3T3_FBROBLST;D;En

Pattern: metacluster_1/pattern_20

Significance: 0.0217304

Absent
LRG_INTSTN;A;CL

Pattern: metacluster_0/pattern_11

Significance: 0.055524800000000006

Absent
Hnd_BRN;P0;D;En

Pattern: metacluster_1/pattern_6

Significance: 0.0104587

Absent
CLP;A;CL

Pattern: metacluster_1/pattern_21

Significance: 0.056897

Absent
npES;3rd_Rhmbmr_delA;E8.5;A;GEO

Pattern: metacluster_0/pattern_16

Significance: 0.0105947

Absent
npES;3rd_Rhmbmr_delC;E8.5;A;GEO

Pattern: metacluster_0/pattern_14

Significance: 0.013260299999999997

Absent
npES;5th_Rhmbmr_delC;E8.5;A;GEO

Pattern: metacluster_1/pattern_17

Significance: 7.43736e-05

Absent
wES;5th_Rhmbmr;E9.5;A;GEO

Pattern: metacluster_0/pattern_6

Significance: 0.000408861

Absent
Unique Cell types only Homer finds Hoxa2: #5

Cell typeModiscoHomer
BRN;OLFTRY_BLB;A;CLAbsent

Pattern: motif7.motif

Significance: 0.03359430000000001

LRG_INTSTN;8wks;D;EnAbsent

Pattern: motif4.motif

Significance: 0.0510414

wES.CRNL_NRL_CRST;E10.5;A;GEOAbsent

Pattern: motif3.motif

Significance: 0.0537414

Melanotrope;A;GEOAbsent

Pattern: motif17.motif

Significance: 0.0132613

CN_PHT_RCPTR;A;GEOAbsent

Pattern: motif8.motif

Significance: 0.012729899999999999