In [1]:
# Parameters
data_name = "Nkx6-1"
task_idxs = "0-213,216-278"
homer_root = "/srv/scratch/msharmin/mouse_hem/with_tfd/full_mouse50/Naive_scans"
modisco_root = "/srv/scratch/msharmin/mouse_hem/with_tfd/full_mouse50/Naive_modisco2019"
overwrite = False
In [2]:
from matlas.reports import collect_motifDB_to_be_displayed, display_comparative_cell_types

load data from labcluster

Using TensorFlow backend.
2019-08-23 11:24:49,884 [WARNING] git-lfs not installed
In [3]:
homer_matches, modisco_matches = collect_motifDB_to_be_displayed(task_idxs, homer_root, modisco_root, 
                                                              overwrite=False)

TF-MoDISco is using the TensorFlow backend.
In [4]:
display_comparative_cell_types(data_name, homer_matches, modisco_matches)
Nkx6-1: Motif: M00466_2.00



Forward PWM

Reverse PWM

Shared Cell types both TF-MoDISco and Homer finds Nkx6-1: #14

Cell typeModiscoHomer
wES;limb;E11.5;D;En

Pattern: metacluster_0/pattern_3

Significance: 0.00893137

/

Pattern: metacluster_0/pattern_5

Significance: 0.029466000000000003

Pattern: motif4.motif

Significance: 0.0564384

/

Pattern: motif8.motif

Significance: 0.027076299999999998

wES;Hnd_lmb;E11.5;D;En

Pattern: metacluster_0/pattern_1

Significance: 0.0142892

/

Pattern: metacluster_0/pattern_3

Significance: 0.0167381

Pattern: motif3.motif

Significance: 0.056808800000000007

BCK_SKN;A;GEO

Pattern: metacluster_0/pattern_6

Significance: 0.042794099999999995

Pattern: motif9.motif

Significance: 0.0530314

RTN;D1;D;En

Pattern: metacluster_0/pattern_3

Significance: 0.029169099999999996

Pattern: motif2.motif

Significance: 0.042199400000000005

wES;RTN;E11.5;D;En

Pattern: metacluster_0/pattern_1

Significance: 0.0509216

Pattern: motif3.motif

Significance: 0.054024699999999995

iVIP_NRN;A;GEO

Pattern: metacluster_1/pattern_6

Significance: 0.035117699999999995

Pattern: motif3.motif

Significance: 0.045032199999999994

G_NRN_P;A;GEO

Pattern: metacluster_1/pattern_14

Significance: 0.05381609999999999

Pattern: motif13.motif

Significance: 0.0436039

wES;MSDRM;E11.5;D;En

Pattern: metacluster_0/pattern_5

Significance: 0.00500802

Pattern: motif2.motif

Significance: 0.0463649

Muller;P12;D;En

Pattern: metacluster_1/pattern_5

Significance: 0.0214238

Pattern: motif4.motif

Significance: 0.0149477

wES;WHL_BRN;E14.5;D;GEO

Pattern: metacluster_0/pattern_0

Significance: 0.0409713

Pattern: motif2.motif

Significance: 0.04298180000000001

wES.Fr_BRN;E14.4;D;En

Pattern: metacluster_0/pattern_2

Significance: 0.041387400000000005

Pattern: motif2.motif

Significance: 0.0438853

wES;Hnd_BRN;E14.5;D;En

Pattern: metacluster_0/pattern_3

Significance: 0.0239296

/

Pattern: metacluster_0/pattern_8

Significance: 0.04881

Pattern: motif3.motif

Significance: 0.0256959

Md_BRN;D;En

Pattern: metacluster_1/pattern_3

Significance: 0.0203949

Pattern: motif14.motif

Significance: 0.055678399999999996

wES;WHL_BRN;E14.5;D;En

Pattern: metacluster_1/pattern_0

Significance: 0.0280269

Pattern: motif2.motif

Significance: 0.0380707

Unique Cell types only TF-MoDISco finds Nkx6-1: #16

Cell typeModiscoHomer
wES;5th_Rhmbmr;E8.5;A;GEO

Pattern: metacluster_0/pattern_25

Significance: 0.039114499999999996

Absent
npES;5th_Rhmbmr_delA;E8.5;A;GEO

Pattern: metacluster_0/pattern_11

Significance: 0.050239599999999995

/

Pattern: metacluster_0/pattern_20

Significance: 0.00837683

Absent
wES;Fr_lmb;E11.5;D;En

Pattern: metacluster_1/pattern_4

Significance: 0.029044099999999996

/

Pattern: metacluster_1/pattern_13

Significance: 0.0219951

Absent
wES;posterior;2;E9.5;A;GEO

Pattern: metacluster_0/pattern_21

Significance: 0.052224099999999996

Absent
wES;FaceP;E14.5;D;En

Pattern: metacluster_0/pattern_7

Significance: 0.0322059

Absent
wES;posterior;1;E8.5;A;GEO

Pattern: metacluster_0/pattern_18

Significance: 0.0471229

Absent
npES;posterior_delA;E8.5;A;GEO

Pattern: metacluster_0/pattern_5

Significance: 0.037955800000000005

/

Pattern: metacluster_0/pattern_6

Significance: 0.0260274

Absent
npES;posterior_delC;E8.5;A;GEO

Pattern: metacluster_0/pattern_6

Significance: 0.0146656

Absent
CRBL_GRNL_Precrsr;A;GEO

Pattern: metacluster_0/pattern_6

Significance: 0.0195241

Absent
NPC;G4;A;GEO

Pattern: metacluster_1/pattern_18

Significance: 0.049647500000000004

Absent
ThMS_MEC;Aire++;A;GEO

Pattern: metacluster_1/pattern_13

Significance: 0.046988999999999996

Absent
Fr_BRN;P0;D;En

Pattern: metacluster_1/pattern_10

Significance: 0.036181300000000007

Absent
Hnd_BRN;P0;D;En

Pattern: metacluster_1/pattern_6

Significance: 0.033262099999999996

Absent
wES;Md_BRN;E14.4;D;En

Pattern: metacluster_0/pattern_6

Significance: 0.0496017

Absent
npES;3rd_Rhmbmr_delA;E8.5;A;GEO

Pattern: metacluster_0/pattern_16

Significance: 0.0189707

Absent
npES;3rd_Rhmbmr_delC;E8.5;A;GEO

Pattern: metacluster_0/pattern_14

Significance: 0.045574800000000006

Absent
Unique Cell types only Homer finds Nkx6-1: #3

Cell typeModiscoHomer
wES.CRNL_NRL_CRST;E10.5;A;GEOAbsent

Pattern: motif3.motif

Significance: 0.0369695

KDNY;P0;D;EnAbsent

Pattern: motif4.motif

Significance: 0.019231

Melanotrope;A;GEOAbsent

Pattern: motif17.motif

Significance: 0.028077800000000003