In [1]:
# Parameters
data_name = "Hoxa1"
task_idxs = "0-213,216-278"
homer_root = "/srv/scratch/msharmin/mouse_hem/with_tfd/full_mouse50/Naive_scans"
modisco_root = "/srv/scratch/msharmin/mouse_hem/with_tfd/full_mouse50/Naive_modisco2019"
overwrite = False
In [2]:
from matlas.reports import collect_motifDB_to_be_displayed, display_comparative_cell_types

load data from labcluster

Using TensorFlow backend.
2019-08-23 11:11:48,502 [WARNING] git-lfs not installed
In [3]:
homer_matches, modisco_matches = collect_motifDB_to_be_displayed(task_idxs, homer_root, modisco_root, 
                                                              overwrite=False)

TF-MoDISco is using the TensorFlow backend.
In [4]:
display_comparative_cell_types(data_name, homer_matches, modisco_matches)
Hoxa1: Motif: M00450_2.00



Forward PWM

Reverse PWM

Shared Cell types both TF-MoDISco and Homer finds Hoxa1: #24

Cell typeModiscoHomer
wES;limb;E11.5;D;En

Pattern: metacluster_0/pattern_3

Significance: 3.56695e-05

Pattern: motif4.motif

Significance: 0.039374099999999995

/

Pattern: motif8.motif

Significance: 0.0290743

wES;Hnd_lmb;E11.5;D;En

Pattern: metacluster_0/pattern_3

Significance: 2.2063000000000002e-05

Pattern: motif3.motif

Significance: 0.0187877

wES;FaceP;E14.5;D;En

Pattern: metacluster_0/pattern_7

Significance: 0.0319054

Pattern: motif14.motif

Significance: 0.0544563

BL_CN_PHT_RCPTR;A;GEO

Pattern: metacluster_1/pattern_18

Significance: 0.0310638

Pattern: motif13.motif

Significance: 0.013153999999999999

wES;3rd_Rhmbmr;E8.5;A;GEO

Pattern: metacluster_0/pattern_21

Significance: 0.0173422

Pattern: motif16.motif

Significance: 0.0150715

wES;5th_Rhmbmr;E8.5;A;GEO

Pattern: metacluster_0/pattern_9

Significance: 0.00552438

/

Pattern: metacluster_0/pattern_25

Significance: 0.00385457

Pattern: motif4.motif

Significance: 0.050742199999999994

npES;5th_Rhmbmr_delA;E8.5;A;GEO

Pattern: metacluster_0/pattern_11

Significance: 0.00720406

/

Pattern: metacluster_0/pattern_20

Significance: 0.0127158

Pattern: motif20.motif

Significance: 0.023571900000000003

wES;posterior;1;E8.5;A;GEO

Pattern: metacluster_0/pattern_11

Significance: 0.00753441

/

Pattern: metacluster_0/pattern_18

Significance: 0.00347908

Pattern: motif6.motif

Significance: 0.006337

npES;posterior_delA;E8.5;A;GEO

Pattern: metacluster_0/pattern_5

Significance: 0.0201988

Pattern: motif5.motif

Significance: 0.0351814

npES;posterior_delC;E8.5;A;GEO

Pattern: metacluster_0/pattern_6

Significance: 2.61743e-07

/

Pattern: metacluster_0/pattern_7

Significance: 0.0125961

Pattern: motif7.motif

Significance: 0.0451659

BCK_SKN;A;GEO

Pattern: metacluster_0/pattern_6

Significance: 0.00296525

Pattern: motif9.motif

Significance: 0.0063939999999999995

iVIP_NRN;A;GEO

Pattern: metacluster_1/pattern_6

Significance: 0.0359829

Pattern: motif3.motif

Significance: 0.0156438

G_NRN_P;A;GEO

Pattern: metacluster_1/pattern_14

Significance: 0.0029430999999999997

Pattern: motif13.motif

Significance: 0.00847391

wES;WHL_BRN;E14.5;D;GEO

Pattern: metacluster_0/pattern_0

Significance: 0.00161743

Pattern: motif2.motif

Significance: 0.00339586

CRBL_GRNL_Precrsr;A;GEO

Pattern: metacluster_0/pattern_6

Significance: 0.00837561

Pattern: motif6.motif

Significance: 0.011233799999999999

RTN;D1;D;En

Pattern: metacluster_0/pattern_3

Significance: 0.00223737

Pattern: motif2.motif

Significance: 0.0037329999999999998

wES;RTN;E11.5;D;En

Pattern: metacluster_0/pattern_1

Significance: 0.00182144

Pattern: motif3.motif

Significance: 0.00382739

Muller;P12;D;En

Pattern: metacluster_1/pattern_5

Significance: 0.00324348

Pattern: motif4.motif

Significance: 0.00511187

wES.Fr_BRN;E14.4;D;En

Pattern: metacluster_0/pattern_2

Significance: 0.00235711

Pattern: motif2.motif

Significance: 0.00277144

Fr_BRN;P0;D;En

Pattern: metacluster_1/pattern_10

Significance: 0.027206099999999997

Pattern: motif10.motif

Significance: 0.0165168

wES;Hnd_BRN;E14.5;D;En

Pattern: metacluster_0/pattern_3

Significance: 0.0567813

/

Pattern: metacluster_0/pattern_8

Significance: 0.00514135

Pattern: motif3.motif

Significance: 0.0151553

wES;Md_BRN;E14.4;D;En

Pattern: metacluster_0/pattern_6

Significance: 0.00229844

Pattern: motif6.motif

Significance: 0.0132139

Md_BRN;D;En

Pattern: metacluster_1/pattern_3

Significance: 0.00829087

Pattern: motif14.motif

Significance: 0.00433512

wES;WHL_BRN;E14.5;D;En

Pattern: metacluster_1/pattern_0

Significance: 0.00137662

Pattern: motif2.motif

Significance: 0.003173

Unique Cell types only TF-MoDISco finds Hoxa1: #12

Cell typeModiscoHomer
wES;Fr_lmb;E11.5;D;En

Pattern: metacluster_1/pattern_13

Significance: 8.08942e-05

Absent
wES;posterior;2;E9.5;A;GEO

Pattern: metacluster_0/pattern_21

Significance: 0.0183759

Absent
ES;E14;A;GEO

Pattern: metacluster_0/pattern_19

Significance: 0.0412209

Absent
NPC;G4;A;GEO

Pattern: metacluster_1/pattern_18

Significance: 0.043767

Absent
iPV_NRN;A;GEO

Pattern: metacluster_1/pattern_7

Significance: 0.0293974

Absent
wES;MSDRM;E11.5;D;En

Pattern: metacluster_0/pattern_5

Significance: 0.00065895

Absent
Hnd_BRN;P0;D;En

Pattern: metacluster_1/pattern_6

Significance: 0.00483101

Absent
npES;ZHBTC4;Brg1fl_fl;untreat;A;GEO

Pattern: metacluster_1/pattern_21

Significance: 0.0590965

Absent
npES;3rd_Rhmbmr_delA;E8.5;A;GEO

Pattern: metacluster_0/pattern_16

Significance: 0.00270223

Absent
npES;3rd_Rhmbmr_delC;E8.5;A;GEO

Pattern: metacluster_0/pattern_14

Significance: 0.00420043

Absent
npES;5th_Rhmbmr_delC;E8.5;A;GEO

Pattern: metacluster_1/pattern_17

Significance: 0.00581348

Absent
wES;5th_Rhmbmr;E9.5;A;GEO

Pattern: metacluster_0/pattern_6

Significance: 0.0193444

Absent
Unique Cell types only Homer finds Hoxa1: #5

Cell typeModiscoHomer
LRG_INTSTN;8wks;D;EnAbsent

Pattern: motif4.motif

Significance: 0.0510414

wES.CRNL_NRL_CRST;E10.5;A;GEOAbsent

Pattern: motif3.motif

Significance: 0.0360655

Melanotrope;A;GEOAbsent

Pattern: motif17.motif

Significance: 0.011949

CN_PHT_RCPTR;A;GEOAbsent

Pattern: motif8.motif

Significance: 0.012446899999999999

KDNY;P0;D;EnAbsent

Pattern: motif4.motif

Significance: 0.0358894