Namespace(genes='/oak/stanford/groups/akundaje/soumyak/refs/gencode/hg38/hg38.gencode.protein_coding.tss.bed', list='/oak/stanford/groups/akundaje/projects/neuro-variants/variant_summary/ldsc/encode_2024/K562_bias/encode_2024.LV.adipocyte.H.mean.variant_scores.tsv', out_prefix='/oak/stanford/groups/akundaje/projects/neuro-variants/variant_annotations/ldsc/encode_2024/K562_bias/encode_2024.LV.adipocyte.H', peaks='/oak/stanford/groups/akundaje/projects/neuro-variants/data/processed/encode_2024/peaks/overlap/encode_2024.LV.adipocyte.H.overlap.peaks.bed.gz', schema='chrombpnet') Namespace(genes='/oak/stanford/groups/akundaje/soumyak/refs/gencode/hg38/hg38.gencode.protein_coding.tss.bed', list='/oak/stanford/groups/akundaje/projects/neuro-variants/variant_summary/ldsc/encode_2024/K562_bias/encode_2024.LV.adipocyte.H.mean.variant_scores.tsv', out_prefix='/oak/stanford/groups/akundaje/projects/neuro-variants/variant_annotations/ldsc/encode_2024/K562_bias/encode_2024.LV.adipocyte.H', peaks='/oak/stanford/groups/akundaje/projects/neuro-variants/data/processed/encode_2024/peaks/overlap/encode_2024.LV.adipocyte.H.overlap.peaks.bed.gz', schema='chrombpnet') chr pos end allele1 allele2 variant_id 1620045 chr1 11007 11008 G C chr1:11008:G:C 1620046 chr1 11011 11012 G C chr1:11012:G:C 1620047 chr1 13109 13110 A G chr1:13110:A:G 1620048 chr1 13115 13116 G T chr1:13116:G:T 1620049 chr1 13117 13118 G A chr1:13118:G:A Variants table shape: (4542891, 6) annotating with closest genes 0 1 2 3 4 5 6 7 8 9 10 \ 0 chr1 11007 11008 G C chr1:11008:G:C chr1 65419 65420 OR4F5 0 1 chr1 11007 11008 G C chr1:11008:G:C chr1 451677 451678 OR4F29 0 2 chr1 11007 11008 G C chr1:11008:G:C chr1 686653 686654 OR4F16 0 3 chr1 11011 11012 G C chr1:11012:G:C chr1 65419 65420 OR4F5 0 4 chr1 11011 11012 G C chr1:11012:G:C chr1 451677 451678 OR4F29 0 11 12 13 14 0 + ENSG00000186092.7 protein_coding 54412 1 - ENSG00000284733.2 protein_coding 440670 2 - ENSG00000284662.2 protein_coding 675646 3 + ENSG00000186092.7 protein_coding 54408 4 - ENSG00000284733.2 protein_coding 440666 Closest genes table shape: (13628673, 15) annotating with peak overlap chr pos end allele1 allele2 variant_id 0 chr1 817097 817098 A G chr1:817098:A:G 1 chr1 817212 817213 G T chr1:817213:G:T 2 chr1 817236 817237 A C chr1:817237:A:C 3 chr1 1019789 1019790 A G chr1:1019790:A:G 4 chr1 1033564 1033565 A G chr1:1033565:A:G Peak overlap table shape: (11665, 6) chr pos allele1 allele2 variant_id logfc.mean logfc.mean.pval \ 0 chr10 14744 C A chr10:14744:C:A -0.003952 0.352545 1 chr10 15391 G A chr10:15391:G:A -0.005112 0.240131 2 chr10 15394 A G chr10:15394:A:G 0.007963 0.153247 3 chr10 15479 A G chr10:15479:A:G -0.000419 0.721962 4 chr10 17274 C G chr10:17274:C:G -0.001016 0.740224 abs_logfc.mean abs_logfc.mean.pval jsd.mean ... \ 0 0.003952 0.395016 0.009659 ... 1 0.005263 0.268574 0.013323 ... 2 0.007963 0.135386 0.017014 ... 3 0.001625 0.754370 0.009312 ... 4 0.001341 0.778849 0.007744 ... quantile_change.mean.pval abs_quantile_change.mean \ 0 0.402976 0.004065 1 0.479897 0.003280 2 0.515483 0.003926 3 0.804555 0.000899 4 0.730697 0.001380 abs_quantile_change.mean.pval closest_gene_1 gene_distance_1 \ 0 0.451219 TUBB8 59419 1 0.522921 TUBB8 58772 2 0.465907 TUBB8 58769 3 0.837788 TUBB8 58684 4 0.767225 TUBB8 56889 closest_gene_2 gene_distance_2 closest_gene_3 gene_distance_3 \ 0 ZMYND11 115345 DIP2C 674924 1 ZMYND11 114698 DIP2C 674277 2 ZMYND11 114695 DIP2C 674274 3 ZMYND11 114610 DIP2C 674189 4 ZMYND11 112815 DIP2C 672394 peak_overlap 0 False 1 False 2 False 3 False 4 False [5 rows x 38 columns] Annotation table shape: (4542891, 38) DONE Done Annotating