In [1]:
# Parameters
data_name = "Tcfec"
task_idxs = "0-213,216-278"
homer_root = "/srv/scratch/msharmin/mouse_hem/with_tfd/full_mouse50/Naive_scans"
modisco_root = "/srv/scratch/msharmin/mouse_hem/with_tfd/full_mouse50/Naive_modisco2019"
In [2]:
from matlas.modisco_report import call_motifDB_to_be_displayed, display_comparative_cell_types
load data from labcluster
Using TensorFlow backend.
2019-07-26 02:34:50,354 [WARNING] git-lfs not installed
In [3]:
homer_matches, modisco_matches = call_motifDB_to_be_displayed(task_idxs, homer_root, modisco_root)
In [4]:
display_comparative_cell_types(data_name, homer_matches, modisco_matches)
TF-MoDISco is using the TensorFlow backend.

CISBP ID of Tcfec: M0201_1.02

Shared Cell types both TF-MoDISco and Homer finds Tcfec
Cell typeModiscoHomer
bone marrow-derived macrophages (Unstimulated)

Significance: 1.41962e-05

Significance: 5.93822e-05

Primary bone marrow derived dendritic cells (DCs, control vector)

Significance: 1.0266700000000001e-05

Significance: 0.00633782

ch12 wt with drug

Significance: 2.3731700000000002e-05

Significance: 0.014727200000000003

Undifferentiated mouse embryonic stem cells (ZhBTc4)

Significance: 6.14599e-06

Significance: 0.000714563

Unique Cell types only TF-MoDISco finds Tcfec
Cell typeModiscoHomer
MPP

Significance: 0.00257659

absent
NK cells (spleen)

Significance: 3.54712e-05

absent
Large Intestine (adult-8wks)

Significance: 5.43244e-05

absent
mature B cells

Significance: 9.81238e-05

absent
Act B cell

Significance: 5.5858e-05

absent
skeletal muscle tissue(adult-8wks)

Significance: 1.59663e-05

absent
Splenic B cell

Significance: 9.99581e-05

absent
Bone marrow derived pre-B cell

Significance: 7.07674e-05

absent
B220+CD43+ B cells

Significance: 0.000113328

absent
aB LPS+IL4

Significance: 6.44973e-05

absent
aB LPS+IL21

Significance: 0.000126563

absent
aB LPS+a-d-dextran

Significance: 0.00011159

absent
mast cells

Significance: 2.7006100000000002e-05

absent
dendritic cell(100 ng/mL Lipopolysaccharide, 6hours)

Significance: 6.66079e-05

absent
eosinphils (ex-vivo, BalbC)

Significance: 6.88521e-05

absent
dendritic cell(100 ng/mL Lipopolysaccharide, 2hours)

Significance: 2.88369e-05

absent
neutrophils

Significance: 2.34244e-05

absent
NIH3T3

Significance: 3.80627e-05

absent
embryo_posterior part(E8.5, deltaA)

Significance: 8.468729999999999e-05

absent
embryo_posterior part (E8.5, deltaC)

Significance: 0.000162332

absent
CD4-CD8+ TCRhi CD69lo CD24lo (MHCII def mice)

Significance: 7.65188e-05

absent
BMDCs(dendritic cell)

Significance: 6.26216e-05

absent
macrophage

Significance: 0.00042762

absent
DN3a

Significance: 7.060270000000001e-05

absent
vasoactive intestinal peptide-positive (VIP) inhibitory neurons

Significance: 5.73504e-05

absent
ES cells (E14)

Significance: 0.000102347

absent
Adipose

Significance: 0.00010930899999999999

absent
dendritic in vitro differentiated cells

Significance: 1.62909e-05

absent
Brain- Medulla Oblongata

Significance: 5.22146e-05

absent
Undifferentiated mouse embryonic stem cells (ZhBTc4)

Significance: 2.09739e-05

absent
restingB

Significance: 6.18209e-05

absent
Embryonic day 0 (stem cell, ES-CJ7)

Significance: 7.54241e-05

absent
Long Term HSC

Significance: 0.00011541700000000001

absent
fibroblast/NIH-3T3

Significance: 3.91508e-05

absent
Liver (Adult 8 weeks)

Significance: 3.48721e-05

absent
gamma delta TCR Marco

Significance: 6.11546e-05

absent
gamma delta TCR M/S -/-

Significance: 0.00015047

absent
Lung (adult-8wks)

Significance: 6.86638e-05

absent
Blast-cultured splenic CD4+ T-cells

Significance: 5.96135e-05

absent
Whole Brain (E14.5)

Significance: 0.00572893

absent
ILC2

Significance: 8.876790000000001e-05

absent
Mus musculus strain 129S1/SVImJ ES-CJ7 stem cell male embryo

Significance: 1.96149e-05

absent
ch12 wt

Significance: 5.50358e-05

absent
ch12 med14 mt

Significance: 0.000119307

absent
Fibroblast/NIH3T3

Significance: 9.380280000000001e-05

absent
mouse embryo fibroblasts/3T3-L1

Significance: 0.000113076

absent
kidney (P0)

Significance: 8.3069e-05

absent
Liver(E14.5)

Significance: 0.000163511

absent
liver(P0)

Significance: 6.2989e-05

absent
lung(P0)

Significance: 5.48753e-05

absent
cerebellar granule cell precursors(wt)

Significance: 8.54024e-05

absent
CD4-positive, CD25-positive, alpha-beta regulatory T cell(adult-8wks)

Significance: 0.000115479

absent
Mesoderm(E11.5)

Significance: 3.1461500000000004e-05

absent
Muller cell(P12)

Significance: 7.68075e-05

absent
mixed mouse hindbrain(P0)

Significance: 3.19426e-05

absent
midbrain(P0)

Significance: 4.66457e-05

absent
Unique Cell types only Homer finds Tcfec
Cell typeModiscoHomer
CD4+CD8-TCRhi CD69hi CD24hi CD25-(B2m def mice)absent

Significance: 0.00221045

ILC3(WT)absent

Significance: 0.000473045

bone marrow-derived macrophages(Lipid A stimulation 120min)absent

Significance: 0.00248849

NCR+ILC3+IL23absent

Significance: 0.00078248

ZHBTC4 ES doxycycline-treatedabsent

Significance: 0.00342794