# Parameters
data_name = "Sfpi1"
task_idxs = "0-213,216-278"
homer_root = "/srv/scratch/msharmin/mouse_hem/with_tfd/full_mouse50/Naive_scans"
modisco_root = "/srv/scratch/msharmin/mouse_hem/with_tfd/full_mouse50/Naive_modisco2019"

from matlas.modisco_report import call_motifDB_to_be_displayed, display_comparative_cell_types

load data from labcluster

Using TensorFlow backend.
2019-07-26 01:59:28,733 [WARNING] git-lfs not installed

homer_matches, modisco_matches = call_motifDB_to_be_displayed(task_idxs, homer_root, modisco_root)

display_comparative_cell_types(data_name, homer_matches, modisco_matches)

TF-MoDISco is using the TensorFlow backend.

CISBP ID of Sfpi1: M6122_1.02

Shared Cell types both TF-MoDISco and Homer finds Sfpi1

Cell type	Modisco	Homer
MPP	Significance: 2.99964e-05	Significance: 2.06779e-05
proB cells	Significance: 1.3672399999999998e-06	Significance: 0.000108436
preB cells	Significance: 1.8586400000000002e-05	Significance: 0.00020234700000000002
immature B cells	Significance: 2.1303699999999997e-05 Significance: 0.012971799999999999	Significance: 2.57656e-05
mature B cells	Significance: 1.01434e-05	Significance: 0.000182058
Act B cell	Significance: 2.9221900000000002e-05 Significance: 0.00386914	Significance: 1.1177e-05
B1 B cells	Significance: 3.47786e-06	Significance: 0.000169755
GC B cells	Significance: 3.54204e-06 Significance: 0.00279707	Significance: 1.388e-05
Pre-PB	Significance: 2.06362e-06	Significance: 1.1467e-05
Splenic B cell	Significance: 2.53444e-05	Significance: 0.00039962900000000003
Bone marrow derived pre-B cell	Significance: 7.29566e-09	Significance: 3.97353e-06
B220+CD43+ B cells	Significance: 1.44756e-07	Significance: 7.61895e-06
bone marrow-derived macrophages(Lipid A stimulation 120min)	Significance: 1.85303e-07 Significance: 0.0882797	Significance: 9.57107e-06
Murine B-lymphoma cell line(A20 cell line)	Significance: 6.19328e-08	Significance: 0.000208696
dendritic cell(100 ng/mL Lipopolysaccharide, 6hours)	Significance: 4.4840300000000006e-08	Significance: 1.83202e-06
dendritic cell(100 ng/mL Lipopolysaccharide, 2hours)	Significance: 2.77625e-08	Significance: 1.07372e-05
Primary bone marrow derived dendritic cells (DCs, control vector)	Significance: 1.5167700000000003e-06 Significance: 0.0999597	Significance: 5.1997199999999995e-09
acute myeloid leukemia	Significance: 1.9833700000000004e-06	Significance: 2.75786e-06
MEL-GATA-1-ER cell line	Significance: 6.2802e-07	Significance: 4.25316e-05
MEL cell line	Significance: 4.36681e-08	Significance: 3.26738e-07
MEL cell line treated with 125 uM zinc dichloride for 24 hours	Significance: 1.1365899999999999e-05	Significance: 5.454939999999999e-09
BMDCs(dendritic cell)	Significance: 2.3963e-08	Significance: 2.26952e-07
macrophage	Significance: 3.1526800000000004e-07 Significance: 0.0109336	Significance: 8.95345e-08
Megakaryocyte primary cell	Significance: 6.4799600000000004e-09 Significance: 0.0874848	Significance: 5.5878e-08
Megakaryocyte progenitor cell	Significance: 3.0664999999999998e-06	Significance: 1.6127400000000002e-07
Common myeloid progenitor primary cell	Significance: 4.21912e-07 Significance: 0.00380859	Significance: 2.00819e-05
dendritic cell(100 ng/mL Lipopolysaccharide, 4hours)	Significance: 1.32604e-06	Significance: 1.41535e-06
Granulocyte monocyte progenitor primary cell	Significance: 2.4208400000000003e-08 Significance: 0.0504078	Significance: 1.8518299999999997e-08
dendritic in vitro differentiated cells	Significance: 7.42979e-07	Significance: 4.62847e-07
gamma delta TCR Marco	Significance: 1.2292899999999999e-05 Significance: 0.00241422	Significance: 9.163589999999999e-06
ch12 wt	Significance: 1.21481e-07	Significance: 0.000538517
CLP	Significance: 2.5874400000000003e-06 Significance: 0.00293303	Significance: 7.432309999999999e-07

Unique Cell types only TF-MoDISco finds Sfpi1

Cell type	Modisco	Homer
spleen(adult-8wks)	Significance: 2.5075300000000004e-05	absent
aBCD180	Significance: 2.80169e-05	absent
plasma cells	Significance: 3.0285200000000002e-09	absent
aB LPS	Significance: 2.12838e-06	absent
aB LPS+IL4	Significance: 1.67516e-05	absent
bone marrow-derived macrophages (Unstimulated)	Significance: 2.82724e-06 Significance: 0.0981184	absent
aB LPS+a-d-dextran	Significance: 1.3540699999999999e-05	absent
Ckit Mice cells AE9a (AML)	Significance: 0.09285089999999999	absent
mast cells	Significance: 1.14863e-05	absent
basophils	Significance: 7.19395e-06	absent
eosinphils (ex-vivo, BalbC)	Significance: 0.0970227	absent
eosinophils (isolated from spleens, BalbC)	Significance: 9.808129999999999e-05 Significance: 0.0951209	absent
neutrophils	Significance: 6.226669999999999e-06 Significance: 0.091843	absent
mouse spleen B cells, CD43-,CD11b- (immature B cells)	Significance: 1.60719e-09	absent
CH12.LX cell line	Significance: 4.33907e-09	absent
Act B cell 24h with oligomycin	Significance: 7.82439e-09	absent
ch12 med14 mt	Significance: 1.3878100000000001e-06	absent
Short Term HSC	Significance: 1.91888e-05	absent

Unique Cell types only Homer finds Sfpi1

Cell type	Modisco	Homer
MZ B cells	absent	Significance: 2.17632e-06
ch12 with quintuple mt	absent	Significance: 0.00036287900000000003
mouse spleen B cells, CD43-,CD11b- (immature B cells)	absent	Significance: 4.87557e-05
ch12 wt with drug	absent	Significance: 0.000624448