In [1]:
# Parameters
data_name = "Klf16"
task_idxs = "0-213,216-278"
homer_root = "/srv/scratch/msharmin/mouse_hem/with_tfd/full_mouse50/Naive_scans"
modisco_root = "/srv/scratch/msharmin/mouse_hem/with_tfd/full_mouse50/Naive_modisco2019"
In [2]:
from matlas.modisco_report import call_motifDB_to_be_displayed, display_comparative_cell_types
load data from labcluster
Using TensorFlow backend.
2019-07-26 00:39:21,090 [WARNING] git-lfs not installed
In [3]:
homer_matches, modisco_matches = call_motifDB_to_be_displayed(task_idxs, homer_root, modisco_root)
In [4]:
display_comparative_cell_types(data_name, homer_matches, modisco_matches)
TF-MoDISco is using the TensorFlow backend.

CISBP ID of Klf16: M5593_1.02

Shared Cell types both TF-MoDISco and Homer finds Klf16
Cell typeModiscoHomer
Unique Cell types only TF-MoDISco finds Klf16
Cell typeModiscoHomer
TCR SV40-I CD8 T cells isolated D35 from early malignant lesions

Significance: 1.71653e-06

absent
CD25CCR6 DN CD4 (memory CD4+ T cell)

Significance: 1.40814e-06

absent
embryo hindlimb buds (E11.5)

Significance: 1.6737099999999998e-06

absent
proB cells

Significance: 1.7276900000000001e-06

absent
preB cells

Significance: 3.0825e-06

absent
memory TCR SV40-I CD8 T cells isolated D35 from established tumors (with listeria immunization)

Significance: 1.9012000000000001e-06

absent
Invariant NKT (iNKT) cells

Significance: 1.77049e-06

absent
Act B cell

Significance: 6.553610000000001e-07

absent
Mouse hematopoietic suspension cell line positive for CD34(416B cell line)

Significance: 1.08251e-06

absent
dendritic cell(100 ng/mL Lipopolysaccharide, 6hours)

Significance: 6.73199e-07

absent
basophils

Significance: 7.361079999999999e-07

absent
Tfh (CD4+CD44+CXCR5+PD1+CD25-) WT

Significance: 9.79801e-07

absent
embryo_5th rhombomere(E8.5, deltaC)

Significance: 1.03123e-05

absent
CD4+CD8+ CD69lo large (DP precursors)

Significance: 6.51995e-06

absent
CD4+CD8+ CD69lo small (DP precursors)

Significance: 3.2900199999999995e-06

absent
adult skin epithelia

Significance: 0.00018554900000000002

absent
DN3b

Significance: 1.3456999999999999e-06

absent
Granule Neuron Progenitors (wt)

Significance: 4.35749e-06

absent
Thymus MECs (Aire+/+)

Significance: 1.41759e-06

absent
Lung

Significance: 1.7531200000000001e-06

absent
Heart

Significance: 2.67177e-06

absent
Adipose

Significance: 3.7606e-07

absent
placenta

Significance: 5.84064e-06

absent
stomach

Significance: 1.79137e-06

absent
dendritic in vitro differentiated cells

Significance: 1.15541e-06

absent
Long Term HSC

Significance: 2.5452000000000002e-06

absent
ILC2 (Nippo infected)

Significance: 2.2865700000000003e-06

absent
ch12 with quintuple mt

Significance: 2.26692e-06

absent
ch12 wt

Significance: 3.1259100000000003e-06

absent
ch12 wt with drug

Significance: 3.26654e-06

absent
CLP

Significance: 3.1478500000000003e-06

absent
kidney (P0)

Significance: 1.6937200000000001e-06

absent
ESC(129SV/Jae/C57BL6J)

Significance: 6.80289e-06

absent
Adipose tissue

Significance: 1.3019399999999998e-06

absent
ILC3(WT)

Significance: 8.899989999999999e-07

absent
ILC3_AbxGermFree

Significance: 1.2358700000000001e-06

absent
central memory TCR SV40-I CD8 T cells

Significance: 7.002519999999999e-07

absent
Unique Cell types only Homer finds Klf16
Cell typeModiscoHomer
Eye- Neural retinaabsent

Significance: 2.69959e-05

Brain- Frontal Cortexabsent

Significance: 0.0118324

ILC2(WT)absent

Significance: 0.000890492

CD4-positive helper(adult-8wks, Activated primary CD4 effector cells)absent

Significance: 0.015452100000000002

Naive splenic CD4+ T-cellsabsent

Significance: 0.00105555

aB aCD40+IL4absent

Significance: 0.00929462

mast cellsabsent

Significance: 0.0603971