In [1]:
# Parameters
data_name = "Hivep1"
task_idxs = "0-213,216-278"
homer_root = "/srv/scratch/msharmin/mouse_hem/with_tfd/full_mouse50/Naive_scans"
modisco_root = "/srv/scratch/msharmin/mouse_hem/with_tfd/full_mouse50/Naive_modisco2019"
In [2]:
from matlas.modisco_report import call_motifDB_to_be_displayed, display_comparative_cell_types
load data from labcluster
Using TensorFlow backend.
2019-07-26 00:17:16,664 [WARNING] git-lfs not installed
In [3]:
homer_matches, modisco_matches = call_motifDB_to_be_displayed(task_idxs, homer_root, modisco_root)
In [4]:
display_comparative_cell_types(data_name, homer_matches, modisco_matches)
TF-MoDISco is using the TensorFlow backend.

CISBP ID of Hivep1: M6544_1.02

Shared Cell types both TF-MoDISco and Homer finds Hivep1
Cell typeModiscoHomer
Unique Cell types only TF-MoDISco finds Hivep1
Cell typeModiscoHomer
NK cells (liver), CD19-CD3ε-NKp46+DX5+Trail-

Significance: 0.00620988

absent
CD4+CD8-TCRhi CD69hi CD24hi CD25-(B2m def mice)

Significance: 0.000277928

absent
CD4-CD8+ TCRhi CD69lo CD24lo (MHCII def mice)

Significance: 0.00070818

absent
Blast-cultured splenic CD4+ T-cells

Significance: 0.00010844700000000001

absent
Spleen CD8+ T cell (Exhausted)

Significance: 0.000210523

absent
naive transgenic TCR SV40-I CD8 T cells

Significance: 0.00127118

absent
naive CD4+ T (CD4+ CD44-CD62L- CD25-) MUT

Significance: 0.000866867

absent
Unique Cell types only Homer finds Hivep1
Cell typeModiscoHomer
CD4+CD8-TCRhi CD25+ Foxp3+absent

Significance: 0.000523276

ILC2(WT)absent

Significance: 0.000502458

CD4-positive helper(adult-8wks, Activated primary CD4 effector cells)absent

Significance: 0.000443098

aB LPSabsent

Significance: 0.00641608

Regulatory T cells CD4+,CD25+absent

Significance: 0.00058467

aB LPS+a-d-dextranabsent

Significance: 0.00107108

ILC2 precursorabsent

Significance: 7.56237e-05

Activated primary CD4 effector cells, isolated ex vivoabsent

Significance: 0.000573654

mouse spleen B cells, CD43-,CD11b- (immature B cells)absent

Significance: 0.00029518700000000003

CH12.LX cell lineabsent

Significance: 0.00031239

Tfh (CD4+CD44+CXCR5+PD1+CD25-) WTabsent

Significance: 0.00711244

Act B cell 24habsent

Significance: 0.011518299999999999

ch12 med14 mtabsent

Significance: 0.0006888780000000001