# Parameters
data_name = "Erf"
task_idxs = "0-213,216-278"
homer_root = "/srv/scratch/msharmin/mouse_hem/with_tfd/full_mouse50/Naive_scans"
modisco_root = "/srv/scratch/msharmin/mouse_hem/with_tfd/full_mouse50/Naive_modisco2019"

from matlas.modisco_report import call_motifDB_to_be_displayed, display_comparative_cell_types

load data from labcluster

Using TensorFlow backend.
2019-07-25 23:43:39,666 [WARNING] git-lfs not installed

homer_matches, modisco_matches = call_motifDB_to_be_displayed(task_idxs, homer_root, modisco_root)

display_comparative_cell_types(data_name, homer_matches, modisco_matches)

TF-MoDISco is using the TensorFlow backend.

CISBP ID of Erf: M5398_1.02

Shared Cell types both TF-MoDISco and Homer finds Erf

Cell type	Modisco	Homer
embryo_posterior part (E9.5, WT)	Significance: 8.85513e-05	Significance: 0.0023526999999999997
Erythroblasts	Significance: 0.00057415	Significance: 0.00055136
embryo_3rd rhombomere (E8.5, deltaC)	Significance: 8.08204e-05	Significance: 0.0034422
embryo_5th rhombomere(e9.5, wt)	Significance: 1.97811e-05	Significance: 0.00335796

Unique Cell types only TF-MoDISco finds Erf

Cell type	Modisco	Homer
mixed embryonic mouse limb(E14.5)	Significance: 3.4873200000000004e-05	absent
mixed embryonic mouse limb(E11.5)	Significance: 3.30956e-05	absent
embryonic facial prominence(e14.5)	Significance: 1.14848e-05	absent
murine mammary adenocarcinoma cell line(3134 cell line)	Significance: 7.39288e-05	absent
B220+CD43+ B cells	Significance: 4.19113e-05	absent
bone marrow-derived macrophages(Lipid A stimulation 120min)	Significance: 0.00013758	absent
CH12.LX cell line	Significance: 6.44342e-05	absent
dendritic cell(100 ng/mL Lipopolysaccharide, 2hours)	Significance: 8.84317e-05	absent
cholinergic motor neuron cell line MN1 treated with 10 nM methyltrienolone	Significance: 8.21541e-05	absent
MN1 cell line	Significance: 0.000376308	absent
3T3-L1	Significance: 9.34942e-05	absent
embryo_3rd rhombomere (E8.5, deltaA)	Significance: 3.73605e-05	absent
Tfr (CD4+CD44+CXCR5+PD1+CD25+) WT	Significance: 2.58014e-05	absent
embryo_3rd rhombomere (E8.5, wt)	Significance: 5.7880699999999996e-05	absent
Tfr (CD4+CD44+CXCR5+PD1+CD25+) MUT	Significance: 0.000114625	absent
embryo_posterior part(E8.5, deltaA)	Significance: 1.2916e-05	absent
embryo_posterior part (E8.5, deltaC)	Significance: 3.77048e-05	absent
neural progenitor cells(F129)	Significance: 0.000208968	absent
BMDCs(dendritic cell)	Significance: 0.00011108	absent
neural progenitor cells(G4)	Significance: 0.000257799	absent
neural progenitor cells(Ch13)	Significance: 0.00017508200000000002	absent
neural progenitor cells(mE6)	Significance: 0.000277999	absent
ES cells (E14)	Significance: 3.29305e-05	absent
Granule Neuron Progenitors (wt)	Significance: 0.00029062	absent
placenta	Significance: 0.00010749799999999999	absent
pancreas	Significance: 2.74362e-05	absent
fibroblast/NIH-3T3	Significance: 9.091370000000001e-05	absent
Liver (Adult 8 weeks)	Significance: 5.37342e-05	absent
Whole Brain (adult-8wks)	Significance: 6.01576e-05	absent
mouse embryo fibroblasts/3T3-L1	Significance: 5.6287e-05	absent
CLP	Significance: 0.00017297900000000003	absent
Kidney(adult-8wks)	Significance: 1.91466e-05	absent
Liver(adult-8wks)	Significance: 9.49125e-05	absent
E14 ES cells	Significance: 0.000638989	absent
Embryonic Stem Cells(v6.5)	Significance: 0.00022060099999999998	absent
Mus musculus C57BL/6 adipocyte was differentiated from 3T3-L1 (Day 8)	Significance: 0.000281759	absent
Cerebellum	Significance: 6.86178e-05	absent
Mesoderm(E11.5)	Significance: 1.57271e-05	absent
mixed embryonic mouse forebrain(E14.5)	Significance: 8.9585e-05	absent
hindbrain embryo(E14.5)	Significance: 0.000411681	absent
mixed embryonic mouse midbrain(E14.5)	Significance: 0.000867332	absent
midbrain(P0)	Significance: 0.000302017	absent
Whole Brain(E14.5)	Significance: 0.000258357	absent
telencephalon tissue	Significance: 5.55259e-05	absent

Unique Cell types only Homer finds Erf

Cell type	Modisco	Homer
NK cells (spleen)	absent	Significance: 4.52592e-05
memory TCR SV40-I CD8 T cells isolated D7 from established tumors (without listeria immunization)	absent	Significance: 6.259560000000001e-05
memory TCR SV40-I CD8 T cells isolated D14 from established tumors (without listeria immunization)	absent	Significance: 1.3508299999999999e-05
ES_derived Definitive Endoderm	absent	Significance: 0.00347481
blue cone photoreceptors/NrlKO	absent	Significance: 0.00137055
Tfh (CD4+CD44+CXCR5+PD1+CD25-) Mut	absent	Significance: 3.9388e-06
embryo_5th rhombomere(E8.5, deltaC)	absent	Significance: 0.0033713000000000003
testis	absent	Significance: 3.70451e-05
Activated primary T regulatory cells, isolated ex vivo	absent	Significance: 0.00041903400000000004
ILC2 (Nippo infected)	absent	Significance: 3.4038699999999996e-05
Th2 (Nippo infected)	absent	Significance: 1.71675e-05
heart tissue(P0)	absent	Significance: 0.000116631
WT retina	absent	Significance: 0.00324175
Retina(newborn 1 day)	absent	Significance: 0.0017445999999999998
ILC2(WT)	absent	Significance: 3.8767600000000005e-05
CD4-positive helper(adult-8wks, Activated primary CD4 effector cells)	absent	Significance: 7.64721e-05
CD4-positive, CD25-positive, alpha-beta regulatory T cell(adult-8wks)	absent	Significance: 0.00010340200000000001
Activated primary T regulatory cells(adult-8wks)	absent	Significance: 8.39315e-07
Naive CD8+ T cell	absent	Significance: 0.000197445
midbrain embryo(E11.5)	absent	Significance: 0.0464584
TCR SV40-I CD8 T cells isolated D5 from early malignant lesions	absent	Significance: 7.46203e-05
TCR SV40-I CD8 T cells isolated D7 from early malignant lesions	absent	Significance: 0.000422716