# Parameters
data_name = "ILC2precrsr;A;CL"
modisco_root = "/srv/scratch/msharmin/mouse_hem/with_tfd/full_mouse50/Naive_modisco2019"
tomtom_report_root = "http://mitra.stanford.edu/kundaje/msharmin/report/tomtom_outs/cells"
task_dir = "task_81-naivegw"
perf_file = "/srv/scratch/msharmin/mouse_hem/with_tfd/full_mouse50/fineFactorized/task_81-naivegw/NaiveauPRC.txt"
homer_root = "/srv/scratch/msharmin/mouse_hem/with_tfd/full_mouse50/Naive_scans"
reportfile = "/mnt/lab_data/kundaje/msharmin/annotations/filtering samples_MS2.xlsx"
sheetname = "filter23"

from matlas.reports import display_metadata

load data from labcluster

Using TensorFlow backend.
2019-08-30 18:58:45,862 [WARNING] git-lfs not installed

display_metadata(data_name, perf_file, reportfile, sheetname)

Sample Information

MetaData Name	Description
Cell type	ILC2 precursor
Cell Group	Other Immune Cells
Experiment Name	ATAC
Experiment Group	Casellas Lab

Pipeline Output

replicate	Naïve overlap peaks	IDR peaks	TSS enrichment (< 8 is very poor <10 is low)	Final number of unique mapping, dup-filtered, chrM filtered reads	Number of reads in called peak regions	Fraction of reads in called peak regions	Number of reads in promoter regions	Fraction of reads in promoter regions	Number of reads in enhancer regions	Fraction of reads in enhancer regions
rep1	135065	109925	12.5716	46970013	11754990	0.2504	7617609	0.1622	15550122	0.3312

Modelling Metadata

Metric	Value
auPRC	0.5847
Calibrated Recall at 50% FDR	0.207
Number of Positive Examples in Test Data	121656
Number of Negative Examples in Test Data	7949195
Imbalance Ratio in Test Data	0.0151
Test Chromosomes	chr2, chr3, chr19

from matlas.reports import display_paiwise_pattern_comparison
from matlas.reports import display_denovo_patterns

display_denovo_patterns(data_name, modisco_root=modisco_root)

TF-MoDISco is using the TensorFlow backend.

The following two links show list of Denovo Patterns and corresponding Motifs discovered by TF-MoDISco

Click here for Denovo Patterns by TF-MoDISco: #19

Pattern Name	TF Name(s)	Modisco
metacluster_1/pattern_0 # seqlets: 5183 SequenceContrib ScoresHyp_Contrib Scores	Ctcf, Ctcfl
metacluster_1/pattern_1 # seqlets: 4517 SequenceContrib ScoresHyp_Contrib Scores	Ets1, Erg, Fli1, Etv4, Etv2, Elk1, Gabpa, Elk4, Etv5, Spi1, Elk3, Etv6, Fev, XP_911724.4, Elf2, Etv3, Etv1, Spib, Elf1, Elf4, Ehf, Elf5, Irf8, Irf4, Elf3, Spic, Spdef, Zscan10, Stat3
metacluster_1/pattern_2 # seqlets: 3413 SequenceContrib ScoresHyp_Contrib Scores	Sp2, Sp3, Sp1, Klf3, Zfx, Klf6, Sp4, Wt1, Zbtb17, Sp5, Klf1, Egr1, Klf5, Maz, Zfp281, Klf15, Usf2, E2f4, Klf7, Klf4, Klf12, Klf8, Mxi1, Nr1h4, E2f1, Egr2, Sall4, Srebf2, Tfap2c, Rfx1
metacluster_1/pattern_3 # seqlets: 1321 SequenceContrib ScoresHyp_Contrib Scores	Nrf1
metacluster_1/pattern_4 # seqlets: 1275 SequenceContrib ScoresHyp_Contrib Scores	Nfyb, Nfyc, Nfya, Foxi1, Pbx3
metacluster_1/pattern_5 # seqlets: 1267 SequenceContrib ScoresHyp_Contrib Scores	Irf1, Irf2, Irf7, Prdm1, Stat1, Stat2, Batf3, Irf3, Irf9
metacluster_1/pattern_6 # seqlets: 1200 SequenceContrib ScoresHyp_Contrib Scores	Gata4, Gata3, Gata1, Gata2, Mecom, Tal1, Gata6
metacluster_1/pattern_7 # seqlets: 955 SequenceContrib ScoresHyp_Contrib Scores
metacluster_1/pattern_8 # seqlets: 933 SequenceContrib ScoresHyp_Contrib Scores	Atf1, Creb1, Usf1, Atf7, Tfec, Jdp2, Atf2, Bhlhe40, Srebf1, Mitf, Tfe3, Crem, Creb5, Tfeb, Arntl, Xbp1, Mlx, Creb3l2, Clock, Rxrb, Dbp, Atf3, Tef, Hlf, Jun, Npas2, Nfil3, Cebpb, Mafb, Fosl2, Tcfl5
metacluster_1/pattern_9 # seqlets: 740 SequenceContrib ScoresHyp_Contrib Scores	Zfp143, Thap11, Tbx2
metacluster_1/pattern_10 # seqlets: 577 SequenceContrib ScoresHyp_Contrib Scores
metacluster_1/pattern_11 # seqlets: 545 SequenceContrib ScoresHyp_Contrib Scores	Rfx3, Rfx2, Rfx4, Rfx7, Rfx6, Sox2
metacluster_1/pattern_12 # seqlets: 542 SequenceContrib ScoresHyp_Contrib Scores	Runx1, Runx2, Cbfb, Runx3
metacluster_1/pattern_13 # seqlets: 461 SequenceContrib ScoresHyp_Contrib Scores	Nfkb2, Nfkb1, Rela, Relb, Rel
metacluster_1/pattern_14 # seqlets: 454 SequenceContrib ScoresHyp_Contrib Scores	Taf1, Yy1, Zfp42
metacluster_1/pattern_15 # seqlets: 243 SequenceContrib ScoresHyp_Contrib Scores
metacluster_1/pattern_16 # seqlets: 159 SequenceContrib ScoresHyp_Contrib Scores
metacluster_1/pattern_17 # seqlets: 113 SequenceContrib ScoresHyp_Contrib Scores	Nfia, Nfib, Nfic
metacluster_1/pattern_18 # seqlets: 108 SequenceContrib ScoresHyp_Contrib Scores	Fos, Fosl1, Jund, Fosb, Batf, Junb, Mafk, Bach2, Mafa, Maff, Nfe2l2, Nfatc1

Click here for Motifs by TF-MoDISco: #150

TF Name	Pattern(s)
Ctcf	Pattern Name Modisco Significance metacluster_1/pattern_0 1.07877e-15 metacluster_1/pattern_2 0.0373611
Ctcfl	Pattern Name Modisco Significance metacluster_1/pattern_0 3.3206600000000003e-07 metacluster_1/pattern_2 0.00271971
Ets1	Pattern Name Modisco Significance metacluster_1/pattern_1 0.00110189
Erg	Pattern Name Modisco Significance metacluster_1/pattern_1 0.00110189
Fli1	Pattern Name Modisco Significance metacluster_1/pattern_1 0.00110189 metacluster_1/pattern_2 0.038612400000000005
Etv4	Pattern Name Modisco Significance metacluster_1/pattern_1 0.00110189
Etv2	Pattern Name Modisco Significance metacluster_1/pattern_1 4.78044e-05
Elk1	Pattern Name Modisco Significance metacluster_1/pattern_1 0.00124395
Gabpa	Pattern Name Modisco Significance metacluster_1/pattern_1 0.00110189
Elk4	Pattern Name Modisco Significance metacluster_1/pattern_1 0.00129937
Etv5	Pattern Name Modisco Significance metacluster_1/pattern_1 0.000447575
Spi1	Pattern Name Modisco Significance metacluster_1/pattern_1 0.035345
Elk3	Pattern Name Modisco Significance metacluster_1/pattern_1 0.00110189
Etv6	Pattern Name Modisco Significance metacluster_1/pattern_1 0.000973186
Fev	Pattern Name Modisco Significance metacluster_1/pattern_1 0.00098848
XP_911724.4	Pattern Name Modisco Significance metacluster_1/pattern_1 0.00110189
Elf2	Pattern Name Modisco Significance metacluster_1/pattern_1 0.00829722 metacluster_1/pattern_15 0.0549754
Etv3	Pattern Name Modisco Significance metacluster_1/pattern_1 0.00110189
Etv1	Pattern Name Modisco Significance metacluster_1/pattern_1 0.00135857
Spib	Pattern Name Modisco Significance metacluster_1/pattern_1 0.00241008 metacluster_1/pattern_5 0.0112113
Elf1	Pattern Name Modisco Significance metacluster_1/pattern_1 0.0030614
Elf4	Pattern Name Modisco Significance metacluster_1/pattern_1 0.00491194
Ehf	Pattern Name Modisco Significance metacluster_1/pattern_1 0.00952298
Elf5	Pattern Name Modisco Significance metacluster_1/pattern_1 0.027644
Irf8	Pattern Name Modisco Significance metacluster_1/pattern_1 0.012934999999999999 metacluster_1/pattern_5 2.1532e-05
Irf4	Pattern Name Modisco Significance metacluster_1/pattern_1 0.015706499999999998 metacluster_1/pattern_5 0.0112113
Elf3	Pattern Name Modisco Significance metacluster_1/pattern_1 0.018035699999999998
Spic	Pattern Name Modisco Significance metacluster_1/pattern_1 0.048226099999999994
Spdef	Pattern Name Modisco Significance metacluster_1/pattern_1 0.0210907
Zscan10	Pattern Name Modisco Significance metacluster_1/pattern_1 0.0371856
Stat3	Pattern Name Modisco Significance metacluster_1/pattern_1 0.0380635
Sp2	Pattern Name Modisco Significance metacluster_1/pattern_2 1.1342299999999999e-18 metacluster_1/pattern_14 7.68218e-05
Sp3	Pattern Name Modisco Significance metacluster_1/pattern_2 1.87263e-12 metacluster_1/pattern_14 0.000998209
Sp1	Pattern Name Modisco Significance metacluster_1/pattern_2 0.00039617300000000004 metacluster_1/pattern_14 7.68218e-05
Klf3	Pattern Name Modisco Significance metacluster_1/pattern_2 3.33519e-09 metacluster_1/pattern_14 0.0242417
Zfx	Pattern Name Modisco Significance metacluster_1/pattern_2 0.00178037 metacluster_1/pattern_14 0.00551004
Klf6	Pattern Name Modisco Significance metacluster_1/pattern_2 1.548e-06
Sp4	Pattern Name Modisco Significance metacluster_1/pattern_2 0.003993399999999999 metacluster_1/pattern_14 0.0562625
Wt1	Pattern Name Modisco Significance metacluster_1/pattern_2 3.41287e-05 metacluster_1/pattern_14 0.031439499999999995
Zbtb17	Pattern Name Modisco Significance metacluster_1/pattern_2 3.69276e-05 metacluster_1/pattern_14 0.0128358
Sp5	Pattern Name Modisco Significance metacluster_1/pattern_2 4.35924e-05
Klf1	Pattern Name Modisco Significance metacluster_1/pattern_2 0.000119321
Egr1	Pattern Name Modisco Significance metacluster_1/pattern_2 0.00524218
Klf5	Pattern Name Modisco Significance metacluster_1/pattern_2 0.000267975
Maz	Pattern Name Modisco Significance metacluster_1/pattern_2 0.000519604 metacluster_1/pattern_14 0.027449599999999998
Zfp281	Pattern Name Modisco Significance metacluster_1/pattern_2 0.0012905
Klf15	Pattern Name Modisco Significance metacluster_1/pattern_2 0.0005646890000000001
Usf2	Pattern Name Modisco Significance metacluster_1/pattern_2 0.0019660999999999997 metacluster_1/pattern_8 0.0321325
E2f4	Pattern Name Modisco Significance metacluster_1/pattern_2 0.00228187
Klf7	Pattern Name Modisco Significance metacluster_1/pattern_2 0.00265485
Klf4	Pattern Name Modisco Significance metacluster_1/pattern_2 0.00339955 metacluster_1/pattern_18 0.0467816
Klf12	Pattern Name Modisco Significance metacluster_1/pattern_2 0.00520652
Klf8	Pattern Name Modisco Significance metacluster_1/pattern_2 0.0054412
Mxi1	Pattern Name Modisco Significance metacluster_1/pattern_2 0.00562692 metacluster_1/pattern_14 0.042598699999999996
Nr1h4	Pattern Name Modisco Significance metacluster_1/pattern_2 0.012335299999999999
E2f1	Pattern Name Modisco Significance metacluster_1/pattern_2 0.0131196
Egr2	Pattern Name Modisco Significance metacluster_1/pattern_2 0.0131196 metacluster_1/pattern_14 0.05466939999999999
Sall4	Pattern Name Modisco Significance metacluster_1/pattern_2 0.028307
Srebf2	Pattern Name Modisco Significance metacluster_1/pattern_2 0.042113199999999996 metacluster_1/pattern_8 0.014016899999999999
Tfap2c	Pattern Name Modisco Significance metacluster_1/pattern_2 0.0479588
Rfx1	Pattern Name Modisco Significance metacluster_1/pattern_2 0.0488507 metacluster_1/pattern_11 2.24071e-09 metacluster_1/pattern_14 0.0128358
Nrf1	Pattern Name Modisco Significance metacluster_1/pattern_3 2.41982e-07
Nfyb	Pattern Name Modisco Significance metacluster_1/pattern_4 2.82345e-11
Nfyc	Pattern Name Modisco Significance metacluster_1/pattern_4 1.38004e-10
Nfya	Pattern Name Modisco Significance metacluster_1/pattern_4 2.9422500000000003e-09
Foxi1	Pattern Name Modisco Significance metacluster_1/pattern_4 6.23105e-06
Pbx3	Pattern Name Modisco Significance metacluster_1/pattern_4 8.64545e-06
Irf1	Pattern Name Modisco Significance metacluster_1/pattern_5 6.494849999999999e-16
Irf2	Pattern Name Modisco Significance metacluster_1/pattern_5 0.000745087
Irf7	Pattern Name Modisco Significance metacluster_1/pattern_5 5.56788e-05
Prdm1	Pattern Name Modisco Significance metacluster_1/pattern_5 5.7887100000000004e-05
Stat1	Pattern Name Modisco Significance metacluster_1/pattern_5 5.7887100000000004e-05
Stat2	Pattern Name Modisco Significance metacluster_1/pattern_5 0.00215208
Batf3	Pattern Name Modisco Significance metacluster_1/pattern_5 0.00215208
Irf3	Pattern Name Modisco Significance metacluster_1/pattern_5 0.00217773
Irf9	Pattern Name Modisco Significance metacluster_1/pattern_5 0.00221592
Gata4	Pattern Name Modisco Significance metacluster_1/pattern_6 0.00921178
Gata3	Pattern Name Modisco Significance metacluster_1/pattern_6 0.0561466
Gata1	Pattern Name Modisco Significance metacluster_1/pattern_6 0.019524
Gata2	Pattern Name Modisco Significance metacluster_1/pattern_6 0.00456395
Mecom	Pattern Name Modisco Significance metacluster_1/pattern_6 0.00655018
Tal1	Pattern Name Modisco Significance metacluster_1/pattern_6 0.00921178
Gata6	Pattern Name Modisco Significance metacluster_1/pattern_6 0.032845
Atf1	Pattern Name Modisco Significance metacluster_1/pattern_8 0.0207475
Creb1	Pattern Name Modisco Significance metacluster_1/pattern_8 0.0056437
Usf1	Pattern Name Modisco Significance metacluster_1/pattern_8 0.011561700000000001
Atf7	Pattern Name Modisco Significance metacluster_1/pattern_8 0.00848165
Tfec	Pattern Name Modisco Significance metacluster_1/pattern_8 0.026954099999999998
Jdp2	Pattern Name Modisco Significance metacluster_1/pattern_8 0.0124279 metacluster_1/pattern_18 0.000818048
Atf2	Pattern Name Modisco Significance metacluster_1/pattern_8 0.00899812
Bhlhe40	Pattern Name Modisco Significance metacluster_1/pattern_8 0.0481111
Srebf1	Pattern Name Modisco Significance metacluster_1/pattern_8 0.014223900000000001
Mitf	Pattern Name Modisco Significance metacluster_1/pattern_8 0.0177299
Tfe3	Pattern Name Modisco Significance metacluster_1/pattern_8 0.026954099999999998
Crem	Pattern Name Modisco Significance metacluster_1/pattern_8 0.0124279
Creb5	Pattern Name Modisco Significance metacluster_1/pattern_8 0.0068223
Tfeb	Pattern Name Modisco Significance metacluster_1/pattern_8 0.014223900000000001
Arntl	Pattern Name Modisco Significance metacluster_1/pattern_8 0.0371106
Xbp1	Pattern Name Modisco Significance metacluster_1/pattern_8 0.00963197
Mlx	Pattern Name Modisco Significance metacluster_1/pattern_8 0.00963197
Creb3l2	Pattern Name Modisco Significance metacluster_1/pattern_8 0.0558247
Clock	Pattern Name Modisco Significance metacluster_1/pattern_8 0.0118641
Rxrb	Pattern Name Modisco Significance metacluster_1/pattern_8 0.0217175
Dbp	Pattern Name Modisco Significance metacluster_1/pattern_8 0.0217175
Atf3	Pattern Name Modisco Significance metacluster_1/pattern_8 0.0459559 metacluster_1/pattern_18 0.000348073
Tef	Pattern Name Modisco Significance metacluster_1/pattern_8 0.026954099999999998
Hlf	Pattern Name Modisco Significance metacluster_1/pattern_8 0.026954099999999998
Jun	Pattern Name Modisco Significance metacluster_1/pattern_8 0.0273215 metacluster_1/pattern_18 4.475469999999999e-06
Npas2	Pattern Name Modisco Significance metacluster_1/pattern_8 0.0310981
Nfil3	Pattern Name Modisco Significance metacluster_1/pattern_8 0.0321325
Cebpb	Pattern Name Modisco Significance metacluster_1/pattern_8 0.0571749
Mafb	Pattern Name Modisco Significance metacluster_1/pattern_8 0.0459559 metacluster_1/pattern_18 0.051607400000000005
Fosl2	Pattern Name Modisco Significance metacluster_1/pattern_8 0.046725800000000005 metacluster_1/pattern_18 3.7844499999999997e-07
Tcfl5	Pattern Name Modisco Significance metacluster_1/pattern_8 0.0571749
Zfp143	Pattern Name Modisco Significance metacluster_1/pattern_9 1.3269799999999999e-21
Thap11	Pattern Name Modisco Significance metacluster_1/pattern_9 2.0166699999999998e-19
Tbx2	Pattern Name Modisco Significance metacluster_1/pattern_9 1.24378e-13
Rfx3	Pattern Name Modisco Significance metacluster_1/pattern_11 0.000631364
Rfx2	Pattern Name Modisco Significance metacluster_1/pattern_11 0.0111439
Rfx4	Pattern Name Modisco Significance metacluster_1/pattern_11 5.91058e-05
Rfx7	Pattern Name Modisco Significance metacluster_1/pattern_11 0.000529718
Rfx6	Pattern Name Modisco Significance metacluster_1/pattern_11 0.000691787
Sox2	Pattern Name Modisco Significance metacluster_1/pattern_11 0.0554679
Runx1	Pattern Name Modisco Significance metacluster_1/pattern_12 0.00597807
Runx2	Pattern Name Modisco Significance metacluster_1/pattern_12 0.04063169999999999
Cbfb	Pattern Name Modisco Significance metacluster_1/pattern_12 0.00155154
Runx3	Pattern Name Modisco Significance metacluster_1/pattern_12 0.0245803
Nfkb2	Pattern Name Modisco Significance metacluster_1/pattern_13 2.7581900000000003e-06
Nfkb1	Pattern Name Modisco Significance metacluster_1/pattern_13 5.38546e-05
Rela	Pattern Name Modisco Significance metacluster_1/pattern_13 0.00030370799999999997
Relb	Pattern Name Modisco Significance metacluster_1/pattern_13 0.00030370799999999997
Rel	Pattern Name Modisco Significance metacluster_1/pattern_13 0.0190649
Taf1	Pattern Name Modisco Significance metacluster_1/pattern_14 3.30994e-06
Yy1	Pattern Name Modisco Significance metacluster_1/pattern_14 3.30994e-06
Zfp42	Pattern Name Modisco Significance metacluster_1/pattern_14 0.0128358
Nfia	Pattern Name Modisco Significance metacluster_1/pattern_17 0.000128272
Nfib	Pattern Name Modisco Significance metacluster_1/pattern_17 0.000128272
Nfic	Pattern Name Modisco Significance metacluster_1/pattern_17 0.0166785
Fos	Pattern Name Modisco Significance metacluster_1/pattern_18 1.14592e-07
Fosl1	Pattern Name Modisco Significance metacluster_1/pattern_18 0.0455048
Jund	Pattern Name Modisco Significance metacluster_1/pattern_18 0.026554599999999998
Fosb	Pattern Name Modisco Significance metacluster_1/pattern_18 0.000317871
Batf	Pattern Name Modisco Significance metacluster_1/pattern_18 0.000317871
Junb	Pattern Name Modisco Significance metacluster_1/pattern_18 0.000348073
Mafk	Pattern Name Modisco Significance metacluster_1/pattern_18 0.0484017
Bach2	Pattern Name Modisco Significance metacluster_1/pattern_18 0.00477614
Mafa	Pattern Name Modisco Significance metacluster_1/pattern_18 0.013110900000000002
Maff	Pattern Name Modisco Significance metacluster_1/pattern_18 0.0132854
Nfe2l2	Pattern Name Modisco Significance metacluster_1/pattern_18 0.0164293
Nfatc1	Pattern Name Modisco Significance metacluster_1/pattern_18 0.0455048

display_paiwise_pattern_comparison(data_name, modisco_root, homer_root)

Number of CISBP TFs obtained by TF-MoDISco and Homer

Shared TFs between TF-MoDISco and Homer: #55

TF Name	Modisco	Homer
Elf3	Pattern Name Modisco Significance metacluster_1/pattern_1 0.018035699999999998	Pattern Name Homer Significance motif2.motif 0.0344628
Etv6	Pattern Name Modisco Significance metacluster_1/pattern_1 0.000973186	Pattern Name Homer Significance motif2.motif 0.00908634
XP_911724.4	Pattern Name Modisco Significance metacluster_1/pattern_1 0.00110189	Pattern Name Homer Significance motif2.motif 0.00384439
Taf1	Pattern Name Modisco Significance metacluster_1/pattern_14 3.30994e-06	Pattern Name Homer Significance motif21.motif 9.614600000000001e-06
Foxi1	Pattern Name Modisco Significance metacluster_1/pattern_4 6.23105e-06	Pattern Name Homer Significance motif16.motif 0.00462789
Nfya	Pattern Name Modisco Significance metacluster_1/pattern_4 2.9422500000000003e-09	Pattern Name Homer Significance motif16.motif 0.00392264
Elf2	Pattern Name Modisco Significance metacluster_1/pattern_1 0.00829722 metacluster_1/pattern_15 0.0549754	Pattern Name Homer Significance motif2.motif 0.0352546
Irf7	Pattern Name Modisco Significance metacluster_1/pattern_5 5.56788e-05	Pattern Name Homer Significance motif20.motif 0.0326189
Irf2	Pattern Name Modisco Significance metacluster_1/pattern_5 0.000745087	Pattern Name Homer Significance motif20.motif 0.0092345
Gabpa	Pattern Name Modisco Significance metacluster_1/pattern_1 0.00110189	Pattern Name Homer Significance motif2.motif 0.00297519
Stat1	Pattern Name Modisco Significance metacluster_1/pattern_5 5.7887100000000004e-05	Pattern Name Homer Significance motif20.motif 0.0351421
Ctcfl	Pattern Name Modisco Significance metacluster_1/pattern_0 3.3206600000000003e-07 metacluster_1/pattern_2 0.00271971	Pattern Name Homer Significance motif1.motif 0.00254958
Gata3	Pattern Name Modisco Significance metacluster_1/pattern_6 0.0561466	Pattern Name Homer Significance motif18.motif 0.028250400000000002 motif25.motif 0.00697623
Nfkb1	Pattern Name Modisco Significance metacluster_1/pattern_13 5.38546e-05	Pattern Name Homer Significance motif28.motif 0.00171803
Klf7	Pattern Name Modisco Significance metacluster_1/pattern_2 0.00265485	Pattern Name Homer Significance motif3.motif 0.018082400000000002
Ehf	Pattern Name Modisco Significance metacluster_1/pattern_1 0.00952298	Pattern Name Homer Significance motif2.motif 0.0123071
Fli1	Pattern Name Modisco Significance metacluster_1/pattern_1 0.00110189 metacluster_1/pattern_2 0.038612400000000005	Pattern Name Homer Significance motif2.motif 0.00297519
Nrf1	Pattern Name Modisco Significance metacluster_1/pattern_3 2.41982e-07	Pattern Name Homer Significance motif17.motif 0.00315484
Elk1	Pattern Name Modisco Significance metacluster_1/pattern_1 0.00124395	Pattern Name Homer Significance motif2.motif 0.00297519
Elk3	Pattern Name Modisco Significance metacluster_1/pattern_1 0.00110189	Pattern Name Homer Significance motif2.motif 0.00291517
Irf1	Pattern Name Modisco Significance metacluster_1/pattern_5 6.494849999999999e-16	Pattern Name Homer Significance motif20.motif 0.00349918
Stat2	Pattern Name Modisco Significance metacluster_1/pattern_5 0.00215208	Pattern Name Homer Significance motif20.motif 0.028652099999999996
Tbx2	Pattern Name Modisco Significance metacluster_1/pattern_9 1.24378e-13	Pattern Name Homer Significance motif7.motif 1.83083e-05
Irf3	Pattern Name Modisco Significance metacluster_1/pattern_5 0.00217773	Pattern Name Homer Significance motif20.motif 0.044754300000000004
Etv3	Pattern Name Modisco Significance metacluster_1/pattern_1 0.00110189	Pattern Name Homer Significance motif2.motif 0.00384439
Fev	Pattern Name Modisco Significance metacluster_1/pattern_1 0.00098848	Pattern Name Homer Significance motif2.motif 0.000256781
Nfkb2	Pattern Name Modisco Significance metacluster_1/pattern_13 2.7581900000000003e-06	Pattern Name Homer Significance motif28.motif 0.00309821
Elf1	Pattern Name Modisco Significance metacluster_1/pattern_1 0.0030614	Pattern Name Homer Significance motif2.motif 0.000860636
Sp4	Pattern Name Modisco Significance metacluster_1/pattern_2 0.003993399999999999 metacluster_1/pattern_14 0.0562625	Pattern Name Homer Significance motif3.motif 0.018082400000000002
Yy1	Pattern Name Modisco Significance metacluster_1/pattern_14 3.30994e-06	Pattern Name Homer Significance motif21.motif 8.05242e-05
Nfyb	Pattern Name Modisco Significance metacluster_1/pattern_4 2.82345e-11	Pattern Name Homer Significance motif16.motif 0.00102295
Ets1	Pattern Name Modisco Significance metacluster_1/pattern_1 0.00110189	Pattern Name Homer Significance motif2.motif 0.00291517
Erg	Pattern Name Modisco Significance metacluster_1/pattern_1 0.00110189	Pattern Name Homer Significance motif2.motif 0.00297519
Spdef	Pattern Name Modisco Significance metacluster_1/pattern_1 0.0210907	Pattern Name Homer Significance motif2.motif 0.035889599999999994
Elf5	Pattern Name Modisco Significance metacluster_1/pattern_1 0.027644	Pattern Name Homer Significance motif2.motif 0.056979300000000004
Egr1	Pattern Name Modisco Significance metacluster_1/pattern_2 0.00524218	Pattern Name Homer Significance motif3.motif 0.0424836
Etv2	Pattern Name Modisco Significance metacluster_1/pattern_1 4.78044e-05	Pattern Name Homer Significance motif2.motif 2.14222e-05
Ctcf	Pattern Name Modisco Significance metacluster_1/pattern_0 1.07877e-15 metacluster_1/pattern_2 0.0373611	Pattern Name Homer Significance motif1.motif 0.00035926 motif6.motif 0.0557558
Relb	Pattern Name Modisco Significance metacluster_1/pattern_13 0.00030370799999999997	Pattern Name Homer Significance motif28.motif 0.00346558
Etv5	Pattern Name Modisco Significance metacluster_1/pattern_1 0.000447575	Pattern Name Homer Significance motif2.motif 0.000860636
Elk4	Pattern Name Modisco Significance metacluster_1/pattern_1 0.00129937	Pattern Name Homer Significance motif2.motif 0.00297519
Klf8	Pattern Name Modisco Significance metacluster_1/pattern_2 0.0054412	Pattern Name Homer Significance motif3.motif 0.018082400000000002
Prdm1	Pattern Name Modisco Significance metacluster_1/pattern_5 5.7887100000000004e-05	Pattern Name Homer Significance motif20.motif 0.000902604
Klf12	Pattern Name Modisco Significance metacluster_1/pattern_2 0.00520652	Pattern Name Homer Significance motif3.motif 0.018082400000000002
Zfp42	Pattern Name Modisco Significance metacluster_1/pattern_14 0.0128358	Pattern Name Homer Significance motif21.motif 0.0017309
Elf4	Pattern Name Modisco Significance metacluster_1/pattern_1 0.00491194	Pattern Name Homer Significance motif2.motif 0.022509499999999998
Etv1	Pattern Name Modisco Significance metacluster_1/pattern_1 0.00135857	Pattern Name Homer Significance motif2.motif 0.00356836
Nfyc	Pattern Name Modisco Significance metacluster_1/pattern_4 1.38004e-10	Pattern Name Homer Significance motif16.motif 0.00392264
Pbx3	Pattern Name Modisco Significance metacluster_1/pattern_4 8.64545e-06	Pattern Name Homer Significance motif16.motif 0.00462789
Zfp143	Pattern Name Modisco Significance metacluster_1/pattern_9 1.3269799999999999e-21	Pattern Name Homer Significance motif7.motif 5.69566e-08
Thap11	Pattern Name Modisco Significance metacluster_1/pattern_9 2.0166699999999998e-19	Pattern Name Homer Significance motif7.motif 3.2445599999999996e-08
Etv4	Pattern Name Modisco Significance metacluster_1/pattern_1 0.00110189	Pattern Name Homer Significance motif2.motif 0.00297519
Irf8	Pattern Name Modisco Significance metacluster_1/pattern_1 0.012934999999999999 metacluster_1/pattern_5 2.1532e-05	Pattern Name Homer Significance motif20.motif 0.0463577
Spi1	Pattern Name Modisco Significance metacluster_1/pattern_1 0.035345	Pattern Name Homer Significance motif2.motif 0.0344628
Rela	Pattern Name Modisco Significance metacluster_1/pattern_13 0.00030370799999999997	Pattern Name Homer Significance motif28.motif 0.015071200000000002

Unique TF-MoDISco TFs: #95

TF Name	Modisco	Homer
Irf9	Pattern Name Modisco Significance metacluster_1/pattern_5 0.00221592	Absent
Rel	Pattern Name Modisco Significance metacluster_1/pattern_13 0.0190649	Absent
Crem	Pattern Name Modisco Significance metacluster_1/pattern_8 0.0124279	Absent
Runx3	Pattern Name Modisco Significance metacluster_1/pattern_12 0.0245803	Absent
Clock	Pattern Name Modisco Significance metacluster_1/pattern_8 0.0118641	Absent
Runx2	Pattern Name Modisco Significance metacluster_1/pattern_12 0.04063169999999999	Absent
Gata1	Pattern Name Modisco Significance metacluster_1/pattern_6 0.019524	Absent
Mitf	Pattern Name Modisco Significance metacluster_1/pattern_8 0.0177299	Absent
Tal1	Pattern Name Modisco Significance metacluster_1/pattern_6 0.00921178	Absent
Gata2	Pattern Name Modisco Significance metacluster_1/pattern_6 0.00456395	Absent
Junb	Pattern Name Modisco Significance metacluster_1/pattern_18 0.000348073	Absent
Cebpb	Pattern Name Modisco Significance metacluster_1/pattern_8 0.0571749	Absent
Nfic	Pattern Name Modisco Significance metacluster_1/pattern_17 0.0166785	Absent
Klf4	Pattern Name Modisco Significance metacluster_1/pattern_2 0.00339955 metacluster_1/pattern_18 0.0467816	Absent
Zfx	Pattern Name Modisco Significance metacluster_1/pattern_2 0.00178037 metacluster_1/pattern_14 0.00551004	Absent
Cbfb	Pattern Name Modisco Significance metacluster_1/pattern_12 0.00155154	Absent
Jund	Pattern Name Modisco Significance metacluster_1/pattern_18 0.026554599999999998	Absent
Spic	Pattern Name Modisco Significance metacluster_1/pattern_1 0.048226099999999994	Absent
Fosb	Pattern Name Modisco Significance metacluster_1/pattern_18 0.000317871	Absent
Zbtb17	Pattern Name Modisco Significance metacluster_1/pattern_2 3.69276e-05 metacluster_1/pattern_14 0.0128358	Absent
Irf4	Pattern Name Modisco Significance metacluster_1/pattern_1 0.015706499999999998 metacluster_1/pattern_5 0.0112113	Absent
Rfx2	Pattern Name Modisco Significance metacluster_1/pattern_11 0.0111439	Absent
Mafk	Pattern Name Modisco Significance metacluster_1/pattern_18 0.0484017	Absent
Rxrb	Pattern Name Modisco Significance metacluster_1/pattern_8 0.0217175	Absent
Gata6	Pattern Name Modisco Significance metacluster_1/pattern_6 0.032845	Absent
Rfx3	Pattern Name Modisco Significance metacluster_1/pattern_11 0.000631364	Absent
Rfx1	Pattern Name Modisco Significance metacluster_1/pattern_2 0.0488507 metacluster_1/pattern_11 2.24071e-09 metacluster_1/pattern_14 0.0128358	Absent
Mafa	Pattern Name Modisco Significance metacluster_1/pattern_18 0.013110900000000002	Absent
Nfib	Pattern Name Modisco Significance metacluster_1/pattern_17 0.000128272	Absent
Creb3l2	Pattern Name Modisco Significance metacluster_1/pattern_8 0.0558247	Absent
Klf5	Pattern Name Modisco Significance metacluster_1/pattern_2 0.000267975	Absent
Sox2	Pattern Name Modisco Significance metacluster_1/pattern_11 0.0554679	Absent
Rfx4	Pattern Name Modisco Significance metacluster_1/pattern_11 5.91058e-05	Absent
E2f4	Pattern Name Modisco Significance metacluster_1/pattern_2 0.00228187	Absent
Nr1h4	Pattern Name Modisco Significance metacluster_1/pattern_2 0.012335299999999999	Absent
Srebf2	Pattern Name Modisco Significance metacluster_1/pattern_2 0.042113199999999996 metacluster_1/pattern_8 0.014016899999999999	Absent
Mlx	Pattern Name Modisco Significance metacluster_1/pattern_8 0.00963197	Absent
Mxi1	Pattern Name Modisco Significance metacluster_1/pattern_2 0.00562692 metacluster_1/pattern_14 0.042598699999999996	Absent
Mecom	Pattern Name Modisco Significance metacluster_1/pattern_6 0.00655018	Absent
Wt1	Pattern Name Modisco Significance metacluster_1/pattern_2 3.41287e-05 metacluster_1/pattern_14 0.031439499999999995	Absent
Tfe3	Pattern Name Modisco Significance metacluster_1/pattern_8 0.026954099999999998	Absent
Batf3	Pattern Name Modisco Significance metacluster_1/pattern_5 0.00215208	Absent
Creb1	Pattern Name Modisco Significance metacluster_1/pattern_8 0.0056437	Absent
Srebf1	Pattern Name Modisco Significance metacluster_1/pattern_8 0.014223900000000001	Absent
Creb5	Pattern Name Modisco Significance metacluster_1/pattern_8 0.0068223	Absent
Tef	Pattern Name Modisco Significance metacluster_1/pattern_8 0.026954099999999998	Absent
E2f1	Pattern Name Modisco Significance metacluster_1/pattern_2 0.0131196	Absent
Batf	Pattern Name Modisco Significance metacluster_1/pattern_18 0.000317871	Absent
Sp2	Pattern Name Modisco Significance metacluster_1/pattern_2 1.1342299999999999e-18 metacluster_1/pattern_14 7.68218e-05	Absent
Xbp1	Pattern Name Modisco Significance metacluster_1/pattern_8 0.00963197	Absent
Tfeb	Pattern Name Modisco Significance metacluster_1/pattern_8 0.014223900000000001	Absent
Sp5	Pattern Name Modisco Significance metacluster_1/pattern_2 4.35924e-05	Absent
Usf2	Pattern Name Modisco Significance metacluster_1/pattern_2 0.0019660999999999997 metacluster_1/pattern_8 0.0321325	Absent
Tfec	Pattern Name Modisco Significance metacluster_1/pattern_8 0.026954099999999998	Absent
Nfil3	Pattern Name Modisco Significance metacluster_1/pattern_8 0.0321325	Absent
Tcfl5	Pattern Name Modisco Significance metacluster_1/pattern_8 0.0571749	Absent
Runx1	Pattern Name Modisco Significance metacluster_1/pattern_12 0.00597807	Absent
Klf15	Pattern Name Modisco Significance metacluster_1/pattern_2 0.0005646890000000001	Absent
Tfap2c	Pattern Name Modisco Significance metacluster_1/pattern_2 0.0479588	Absent
Atf1	Pattern Name Modisco Significance metacluster_1/pattern_8 0.0207475	Absent
Sall4	Pattern Name Modisco Significance metacluster_1/pattern_2 0.028307	Absent
Zscan10	Pattern Name Modisco Significance metacluster_1/pattern_1 0.0371856	Absent
Hlf	Pattern Name Modisco Significance metacluster_1/pattern_8 0.026954099999999998	Absent
Klf3	Pattern Name Modisco Significance metacluster_1/pattern_2 3.33519e-09 metacluster_1/pattern_14 0.0242417	Absent
Rfx6	Pattern Name Modisco Significance metacluster_1/pattern_11 0.000691787	Absent
Egr2	Pattern Name Modisco Significance metacluster_1/pattern_2 0.0131196 metacluster_1/pattern_14 0.05466939999999999	Absent
Gata4	Pattern Name Modisco Significance metacluster_1/pattern_6 0.00921178	Absent
Dbp	Pattern Name Modisco Significance metacluster_1/pattern_8 0.0217175	Absent
Jdp2	Pattern Name Modisco Significance metacluster_1/pattern_8 0.0124279 metacluster_1/pattern_18 0.000818048	Absent
Bhlhe40	Pattern Name Modisco Significance metacluster_1/pattern_8 0.0481111	Absent
Maz	Pattern Name Modisco Significance metacluster_1/pattern_2 0.000519604 metacluster_1/pattern_14 0.027449599999999998	Absent
Arntl	Pattern Name Modisco Significance metacluster_1/pattern_8 0.0371106	Absent
Klf1	Pattern Name Modisco Significance metacluster_1/pattern_2 0.000119321	Absent
Sp3	Pattern Name Modisco Significance metacluster_1/pattern_2 1.87263e-12 metacluster_1/pattern_14 0.000998209	Absent
Jun	Pattern Name Modisco Significance metacluster_1/pattern_8 0.0273215 metacluster_1/pattern_18 4.475469999999999e-06	Absent
Bach2	Pattern Name Modisco Significance metacluster_1/pattern_18 0.00477614	Absent
Nfe2l2	Pattern Name Modisco Significance metacluster_1/pattern_18 0.0164293	Absent
Fos	Pattern Name Modisco Significance metacluster_1/pattern_18 1.14592e-07	Absent
Usf1	Pattern Name Modisco Significance metacluster_1/pattern_8 0.011561700000000001	Absent
Klf6	Pattern Name Modisco Significance metacluster_1/pattern_2 1.548e-06	Absent
Spib	Pattern Name Modisco Significance metacluster_1/pattern_1 0.00241008 metacluster_1/pattern_5 0.0112113	Absent
Zfp281	Pattern Name Modisco Significance metacluster_1/pattern_2 0.0012905	Absent
Stat3	Pattern Name Modisco Significance metacluster_1/pattern_1 0.0380635	Absent
Maff	Pattern Name Modisco Significance metacluster_1/pattern_18 0.0132854	Absent
Mafb	Pattern Name Modisco Significance metacluster_1/pattern_8 0.0459559 metacluster_1/pattern_18 0.051607400000000005	Absent
Rfx7	Pattern Name Modisco Significance metacluster_1/pattern_11 0.000529718	Absent
Fosl2	Pattern Name Modisco Significance metacluster_1/pattern_8 0.046725800000000005 metacluster_1/pattern_18 3.7844499999999997e-07	Absent
Sp1	Pattern Name Modisco Significance metacluster_1/pattern_2 0.00039617300000000004 metacluster_1/pattern_14 7.68218e-05	Absent
Atf2	Pattern Name Modisco Significance metacluster_1/pattern_8 0.00899812	Absent
Fosl1	Pattern Name Modisco Significance metacluster_1/pattern_18 0.0455048	Absent
Atf7	Pattern Name Modisco Significance metacluster_1/pattern_8 0.00848165	Absent
Npas2	Pattern Name Modisco Significance metacluster_1/pattern_8 0.0310981	Absent
Nfatc1	Pattern Name Modisco Significance metacluster_1/pattern_18 0.0455048	Absent
Nfia	Pattern Name Modisco Significance metacluster_1/pattern_17 0.000128272	Absent
Atf3	Pattern Name Modisco Significance metacluster_1/pattern_8 0.0459559 metacluster_1/pattern_18 0.000348073	Absent

Unique Homer TFs: #2

TF Name	Modisco	Homer
Max	Absent	Pattern Name Homer Significance motif2.motif 0.049177
Zbtb33	Absent	Pattern Name Homer Significance motif15.motif 0.00418928