# Parameters
data_name = "MCRPHG;A;CL"
modisco_root = "/srv/scratch/msharmin/mouse_hem/with_tfd/full_mouse50/Naive_modisco2019"
tomtom_report_root = "http://mitra.stanford.edu/kundaje/msharmin/report/tomtom_outs/cells"
task_dir = "task_44-naivegw"
perf_file = "/srv/scratch/msharmin/mouse_hem/with_tfd/full_mouse50/fineFactorized/task_44-naivegw/NaiveauPRC.txt"
homer_root = "/srv/scratch/msharmin/mouse_hem/with_tfd/full_mouse50/Naive_scans"
reportfile = "/mnt/lab_data/kundaje/msharmin/annotations/filtering samples_MS2.xlsx"
sheetname = "filter23"

from matlas.reports import display_metadata

load data from labcluster

Using TensorFlow backend.
2019-08-30 18:50:18,780 [WARNING] git-lfs not installed

display_metadata(data_name, perf_file, reportfile, sheetname)

Sample Information

MetaData Name	Description
Cell type	macrophage
Cell Group	Other Immune Cells
Experiment Name	ATAC
Experiment Group	Casellas Lab

Pipeline Output

replicate	Naïve overlap peaks	IDR peaks	TSS enrichment (< 8 is very poor <10 is low)	Final number of unique mapping, dup-filtered, chrM filtered reads	Number of reads in called peak regions	Fraction of reads in called peak regions	Number of reads in promoter regions	Fraction of reads in promoter regions	Number of reads in enhancer regions	Fraction of reads in enhancer regions
rep1	172038	135395	11.9041	61426065	19759225	0.3218	9431275	0.1536	26338818	0.4289

Modelling Metadata

Metric	Value
auPRC	0.6318
Calibrated Recall at 50% FDR	0.211
Number of Positive Examples in Test Data	156524
Number of Negative Examples in Test Data	7914327
Imbalance Ratio in Test Data	0.0194
Test Chromosomes	chr2, chr3, chr19

from matlas.reports import display_paiwise_pattern_comparison
from matlas.reports import display_denovo_patterns

display_denovo_patterns(data_name, modisco_root=modisco_root)

TF-MoDISco is using the TensorFlow backend.

The following two links show list of Denovo Patterns and corresponding Motifs discovered by TF-MoDISco

Click here for Denovo Patterns by TF-MoDISco: #23

Pattern Name	TF Name(s)	Modisco
metacluster_1/pattern_0 # seqlets: 7661 SequenceContrib ScoresHyp_Contrib Scores	Spi1, Spib, Irf8, Irf4, Spic, Elf3, Etv2, Prdm1, Irf3, Ehf, Etv4, Irf2, Etv6, Irf1, Ets1, Elf5, Elf4, Etv3, Elf2
metacluster_1/pattern_1 # seqlets: 6498 SequenceContrib ScoresHyp_Contrib Scores	Ctcf, Ctcfl
metacluster_1/pattern_2 # seqlets: 2389 SequenceContrib ScoresHyp_Contrib Scores	Fos, Fosl1, Jund, Fosl2, Batf, Fosb, Junb, Atf3, Jun, Jdp2, Bach2, Mafa, Mafk, Nfe2l2, Bach1, Nfe2, Mafb, Mafg, Maf, Maff
metacluster_1/pattern_3 # seqlets: 2176 SequenceContrib ScoresHyp_Contrib Scores	Stat2, Irf7, Stat1, Zscan10, Irf9
metacluster_1/pattern_4 # seqlets: 1454 SequenceContrib ScoresHyp_Contrib Scores	Sp4, Sp2, Klf3, Sp3, Sp1, Klf6, E2f4, Klf7, Klf4, Klf8, Klf12, Klf1, Egr1, Egr2, Zbtb17, E2f1, Klf5, Sp5, Zfp281, Zfp740, Egr3, Zfx, Zbtb1
metacluster_1/pattern_5 # seqlets: 1047 SequenceContrib ScoresHyp_Contrib Scores	Cebpb, Cebpa, Cebpd, Dbp, Cebpg, Hlf, Nfil3, Atf4, Ddit3, Cebpe, Tef
metacluster_1/pattern_6 # seqlets: 996 SequenceContrib ScoresHyp_Contrib Scores	Mitf, Tfec, Srebf1, Usf1, Bhlhe40, Tfe3, Usf2, Mlx, Tfeb, Arntl, Clock, Npas2, Srebf2, Tcfl5, Bhlhe41, Arnt, Creb3l2
metacluster_1/pattern_7 # seqlets: 795 SequenceContrib ScoresHyp_Contrib Scores	Atf2, Atf7, Creb1, Creb5, Atf1, Crem
metacluster_1/pattern_8 # seqlets: 729 SequenceContrib ScoresHyp_Contrib Scores	Nrf1
metacluster_1/pattern_9 # seqlets: 684 SequenceContrib ScoresHyp_Contrib Scores	Nfyc, Nfyb, Nfya, Foxi1, Pbx3
metacluster_1/pattern_10 # seqlets: 676 SequenceContrib ScoresHyp_Contrib Scores	Thap11, Zfp143, Tbx2
metacluster_1/pattern_11 # seqlets: 687 SequenceContrib ScoresHyp_Contrib Scores
metacluster_1/pattern_12 # seqlets: 323 SequenceContrib ScoresHyp_Contrib Scores	Gabpa, Fli1, Erg, Elk1, Elk4, Elk3, Elf1, Etv5, Etv1, Fev, XP_911724.4
metacluster_1/pattern_13 # seqlets: 253 SequenceContrib ScoresHyp_Contrib Scores	Nr1d2, Rorc, Nr1d1, Nfatc1
metacluster_1/pattern_14 # seqlets: 193 SequenceContrib ScoresHyp_Contrib Scores	Mef2d, Mef2c, Mef2a
metacluster_1/pattern_15 # seqlets: 190 SequenceContrib ScoresHyp_Contrib Scores	Taf1, Yy1, Zfp42, Rfx1, Wt1
metacluster_1/pattern_16 # seqlets: 172 SequenceContrib ScoresHyp_Contrib Scores	Rfx2, Rfx3, Rfx4, Rfx7, Rfx6, Sox2
metacluster_1/pattern_17 # seqlets: 111 SequenceContrib ScoresHyp_Contrib Scores	Runx1, Runx2, Cbfb, Runx3
metacluster_1/pattern_18 # seqlets: 77 SequenceContrib ScoresHyp_Contrib Scores
metacluster_1/pattern_19 # seqlets: 52 SequenceContrib ScoresHyp_Contrib Scores	Nfia
metacluster_1/pattern_20 # seqlets: 47 SequenceContrib ScoresHyp_Contrib Scores
metacluster_1/pattern_21 # seqlets: 46 SequenceContrib ScoresHyp_Contrib Scores
metacluster_1/pattern_22 # seqlets: 44 SequenceContrib ScoresHyp_Contrib Scores	Zbtb33

Click here for Motifs by TF-MoDISco: #147

TF Name	Pattern(s)
Spi1	Pattern Name Modisco Significance metacluster_1/pattern_0 0.00303171 metacluster_1/pattern_3 0.008117000000000001 metacluster_1/pattern_11 0.00891111 metacluster_1/pattern_13 0.0388971
Spib	Pattern Name Modisco Significance metacluster_1/pattern_0 4.08549e-11 metacluster_1/pattern_3 8.608e-07 metacluster_1/pattern_13 0.023193000000000002
Irf8	Pattern Name Modisco Significance metacluster_1/pattern_0 3.9634300000000004e-07 metacluster_1/pattern_3 3.77672e-15
Irf4	Pattern Name Modisco Significance metacluster_1/pattern_0 5.28371e-06 metacluster_1/pattern_3 0.0326039 metacluster_1/pattern_13 0.023193000000000002
Spic	Pattern Name Modisco Significance metacluster_1/pattern_0 0.00486297 metacluster_1/pattern_11 0.00206876
Elf3	Pattern Name Modisco Significance metacluster_1/pattern_0 0.0580664
Etv2	Pattern Name Modisco Significance metacluster_1/pattern_0 0.00958651 metacluster_1/pattern_12 0.042360300000000004
Prdm1	Pattern Name Modisco Significance metacluster_1/pattern_0 0.00958651 metacluster_1/pattern_3 0.00386173
Irf3	Pattern Name Modisco Significance metacluster_1/pattern_0 0.0104884 metacluster_1/pattern_3 0.000681744
Ehf	Pattern Name Modisco Significance metacluster_1/pattern_0 0.021223500000000003 metacluster_1/pattern_12 0.0242813
Etv4	Pattern Name Modisco Significance metacluster_1/pattern_0 0.021223500000000003 metacluster_1/pattern_12 0.018215900000000004 metacluster_1/pattern_13 0.0263301
Irf2	Pattern Name Modisco Significance metacluster_1/pattern_0 0.024373699999999998 metacluster_1/pattern_3 0.0113699
Etv6	Pattern Name Modisco Significance metacluster_1/pattern_0 0.0501549 metacluster_1/pattern_12 0.029810000000000003 metacluster_1/pattern_13 0.023193000000000002
Irf1	Pattern Name Modisco Significance metacluster_1/pattern_0 0.024373699999999998 metacluster_1/pattern_3 1.02706e-05
Ets1	Pattern Name Modisco Significance metacluster_1/pattern_0 0.0580664 metacluster_1/pattern_12 0.0115254
Elf5	Pattern Name Modisco Significance metacluster_1/pattern_0 0.0387776 metacluster_1/pattern_12 0.0314308
Elf4	Pattern Name Modisco Significance metacluster_1/pattern_0 0.0580664 metacluster_1/pattern_12 0.029810000000000003
Etv3	Pattern Name Modisco Significance metacluster_1/pattern_0 0.0580664 metacluster_1/pattern_12 0.029567400000000004
Elf2	Pattern Name Modisco Significance metacluster_1/pattern_0 0.0580664 metacluster_1/pattern_12 0.035716000000000005 metacluster_1/pattern_13 0.023193000000000002
Ctcf	Pattern Name Modisco Significance metacluster_1/pattern_1 2.00493e-15
Ctcfl	Pattern Name Modisco Significance metacluster_1/pattern_1 3.86141e-07
Fos	Pattern Name Modisco Significance metacluster_1/pattern_2 4.64369e-07
Fosl1	Pattern Name Modisco Significance metacluster_1/pattern_2 0.009759499999999999
Jund	Pattern Name Modisco Significance metacluster_1/pattern_2 0.009759499999999999 metacluster_1/pattern_13 0.0598125
Fosl2	Pattern Name Modisco Significance metacluster_1/pattern_2 0.050574 metacluster_1/pattern_7 0.0201107 metacluster_1/pattern_13 0.0598125
Batf	Pattern Name Modisco Significance metacluster_1/pattern_2 0.0190062 metacluster_1/pattern_13 0.042746
Fosb	Pattern Name Modisco Significance metacluster_1/pattern_2 0.00028498900000000003 metacluster_1/pattern_13 0.023193000000000002
Junb	Pattern Name Modisco Significance metacluster_1/pattern_2 0.030732599999999995 metacluster_1/pattern_13 0.023193000000000002
Atf3	Pattern Name Modisco Significance metacluster_1/pattern_2 0.000327321 metacluster_1/pattern_7 0.00479348 metacluster_1/pattern_13 0.023193000000000002
Jun	Pattern Name Modisco Significance metacluster_1/pattern_2 0.047782599999999995 metacluster_1/pattern_7 0.046176999999999996 metacluster_1/pattern_13 0.023193000000000002
Jdp2	Pattern Name Modisco Significance metacluster_1/pattern_2 0.000407175 metacluster_1/pattern_7 0.00168716 metacluster_1/pattern_13 0.0388971
Bach2	Pattern Name Modisco Significance metacluster_1/pattern_2 0.00518615
Mafa	Pattern Name Modisco Significance metacluster_1/pattern_2 0.00681553
Mafk	Pattern Name Modisco Significance metacluster_1/pattern_2 0.009759499999999999
Nfe2l2	Pattern Name Modisco Significance metacluster_1/pattern_2 0.013099000000000001
Bach1	Pattern Name Modisco Significance metacluster_1/pattern_2 0.0117015
Nfe2	Pattern Name Modisco Significance metacluster_1/pattern_2 0.0117015
Mafb	Pattern Name Modisco Significance metacluster_1/pattern_2 0.021782
Mafg	Pattern Name Modisco Significance metacluster_1/pattern_2 0.021782
Maf	Pattern Name Modisco Significance metacluster_1/pattern_2 0.0296281
Maff	Pattern Name Modisco Significance metacluster_1/pattern_2 0.0297733
Stat2	Pattern Name Modisco Significance metacluster_1/pattern_3 0.00368333
Irf7	Pattern Name Modisco Significance metacluster_1/pattern_3 0.004683
Stat1	Pattern Name Modisco Significance metacluster_1/pattern_3 0.00577965
Zscan10	Pattern Name Modisco Significance metacluster_1/pattern_3 0.00861557
Irf9	Pattern Name Modisco Significance metacluster_1/pattern_3 0.0113699
Sp4	Pattern Name Modisco Significance metacluster_1/pattern_4 0.00131222 metacluster_1/pattern_15 0.0554783
Sp2	Pattern Name Modisco Significance metacluster_1/pattern_4 6.348049999999999e-06 metacluster_1/pattern_15 0.000196708 metacluster_1/pattern_22 0.00459682
Klf3	Pattern Name Modisco Significance metacluster_1/pattern_4 6.348049999999999e-06 metacluster_1/pattern_15 0.0554783
Sp3	Pattern Name Modisco Significance metacluster_1/pattern_4 9.4455e-06 metacluster_1/pattern_15 0.00230657 metacluster_1/pattern_22 0.0210026
Sp1	Pattern Name Modisco Significance metacluster_1/pattern_4 0.000456535 metacluster_1/pattern_15 0.000248553 metacluster_1/pattern_22 0.00861558
Klf6	Pattern Name Modisco Significance metacluster_1/pattern_4 0.000403571
E2f4	Pattern Name Modisco Significance metacluster_1/pattern_4 0.000403571
Klf7	Pattern Name Modisco Significance metacluster_1/pattern_4 0.000403571
Klf4	Pattern Name Modisco Significance metacluster_1/pattern_4 0.00861131
Klf8	Pattern Name Modisco Significance metacluster_1/pattern_4 0.000626525
Klf12	Pattern Name Modisco Significance metacluster_1/pattern_4 0.00861131
Klf1	Pattern Name Modisco Significance metacluster_1/pattern_4 0.0332293
Egr1	Pattern Name Modisco Significance metacluster_1/pattern_4 0.0302502
Egr2	Pattern Name Modisco Significance metacluster_1/pattern_4 0.033326 metacluster_1/pattern_15 0.0260923
Zbtb17	Pattern Name Modisco Significance metacluster_1/pattern_4 0.00944787 metacluster_1/pattern_12 0.039552199999999996 metacluster_1/pattern_15 0.0118262 metacluster_1/pattern_22 0.051789699999999994
E2f1	Pattern Name Modisco Significance metacluster_1/pattern_4 0.0161377
Klf5	Pattern Name Modisco Significance metacluster_1/pattern_4 0.018576699999999998
Sp5	Pattern Name Modisco Significance metacluster_1/pattern_4 0.0187459
Zfp281	Pattern Name Modisco Significance metacluster_1/pattern_4 0.033326
Zfp740	Pattern Name Modisco Significance metacluster_1/pattern_4 0.040631400000000005
Egr3	Pattern Name Modisco Significance metacluster_1/pattern_4 0.041667199999999995
Zfx	Pattern Name Modisco Significance metacluster_1/pattern_4 0.05484580000000001 metacluster_1/pattern_15 0.00433036 metacluster_1/pattern_22 0.035924300000000006
Zbtb1	Pattern Name Modisco Significance metacluster_1/pattern_4 0.05775790000000001
Cebpb	Pattern Name Modisco Significance metacluster_1/pattern_5 0.00714947
Cebpa	Pattern Name Modisco Significance metacluster_1/pattern_5 0.00763158 metacluster_1/pattern_7 0.0586466
Cebpd	Pattern Name Modisco Significance metacluster_1/pattern_5 0.00999219
Dbp	Pattern Name Modisco Significance metacluster_1/pattern_5 0.0560054
Cebpg	Pattern Name Modisco Significance metacluster_1/pattern_5 0.0170536
Hlf	Pattern Name Modisco Significance metacluster_1/pattern_5 0.00319918
Nfil3	Pattern Name Modisco Significance metacluster_1/pattern_5 0.00337946 metacluster_1/pattern_7 0.04674280000000001
Atf4	Pattern Name Modisco Significance metacluster_1/pattern_5 0.0230418
Ddit3	Pattern Name Modisco Significance metacluster_1/pattern_5 0.014235499999999998
Cebpe	Pattern Name Modisco Significance metacluster_1/pattern_5 0.0140874
Tef	Pattern Name Modisco Significance metacluster_1/pattern_5 0.0357772
Mitf	Pattern Name Modisco Significance metacluster_1/pattern_6 0.0116726
Tfec	Pattern Name Modisco Significance metacluster_1/pattern_6 0.0141007
Srebf1	Pattern Name Modisco Significance metacluster_1/pattern_6 0.0068334
Usf1	Pattern Name Modisco Significance metacluster_1/pattern_6 0.0254166
Bhlhe40	Pattern Name Modisco Significance metacluster_1/pattern_6 0.0252379
Tfe3	Pattern Name Modisco Significance metacluster_1/pattern_6 0.0165978
Usf2	Pattern Name Modisco Significance metacluster_1/pattern_6 0.0194168 metacluster_1/pattern_12 0.039552199999999996
Mlx	Pattern Name Modisco Significance metacluster_1/pattern_6 0.0383926
Tfeb	Pattern Name Modisco Significance metacluster_1/pattern_6 0.00993503
Arntl	Pattern Name Modisco Significance metacluster_1/pattern_6 0.028758299999999997
Clock	Pattern Name Modisco Significance metacluster_1/pattern_6 0.00561913
Npas2	Pattern Name Modisco Significance metacluster_1/pattern_6 0.0120418
Srebf2	Pattern Name Modisco Significance metacluster_1/pattern_6 0.0166616
Tcfl5	Pattern Name Modisco Significance metacluster_1/pattern_6 0.025986099999999998
Bhlhe41	Pattern Name Modisco Significance metacluster_1/pattern_6 0.04132519999999999
Arnt	Pattern Name Modisco Significance metacluster_1/pattern_6 0.0425872
Creb3l2	Pattern Name Modisco Significance metacluster_1/pattern_6 0.053600800000000004
Atf2	Pattern Name Modisco Significance metacluster_1/pattern_7 0.00117127
Atf7	Pattern Name Modisco Significance metacluster_1/pattern_7 0.000383137
Creb1	Pattern Name Modisco Significance metacluster_1/pattern_7 0.0201107
Creb5	Pattern Name Modisco Significance metacluster_1/pattern_7 0.000441931
Atf1	Pattern Name Modisco Significance metacluster_1/pattern_7 0.0319505
Crem	Pattern Name Modisco Significance metacluster_1/pattern_7 0.0130111
Nrf1	Pattern Name Modisco Significance metacluster_1/pattern_8 4.925899999999999e-07
Nfyc	Pattern Name Modisco Significance metacluster_1/pattern_9 3.59726e-08
Nfyb	Pattern Name Modisco Significance metacluster_1/pattern_9 3.59726e-08
Nfya	Pattern Name Modisco Significance metacluster_1/pattern_9 3.59726e-08
Foxi1	Pattern Name Modisco Significance metacluster_1/pattern_9 4.44778e-06
Pbx3	Pattern Name Modisco Significance metacluster_1/pattern_9 9.89e-06
Thap11	Pattern Name Modisco Significance metacluster_1/pattern_10 4.6510200000000004e-21
Zfp143	Pattern Name Modisco Significance metacluster_1/pattern_10 1.63313e-20
Tbx2	Pattern Name Modisco Significance metacluster_1/pattern_10 4.29228e-14
Gabpa	Pattern Name Modisco Significance metacluster_1/pattern_12 0.00418695
Fli1	Pattern Name Modisco Significance metacluster_1/pattern_12 0.0115254 metacluster_1/pattern_13 0.0388971
Erg	Pattern Name Modisco Significance metacluster_1/pattern_12 0.0115254 metacluster_1/pattern_13 0.0388971
Elk1	Pattern Name Modisco Significance metacluster_1/pattern_12 0.00418695
Elk4	Pattern Name Modisco Significance metacluster_1/pattern_12 0.00437295
Elk3	Pattern Name Modisco Significance metacluster_1/pattern_12 0.00236884
Elf1	Pattern Name Modisco Significance metacluster_1/pattern_12 0.00181956
Etv5	Pattern Name Modisco Significance metacluster_1/pattern_12 0.00382864
Etv1	Pattern Name Modisco Significance metacluster_1/pattern_12 0.00567679
Fev	Pattern Name Modisco Significance metacluster_1/pattern_12 0.00437295
XP_911724.4	Pattern Name Modisco Significance metacluster_1/pattern_12 0.0368601
Nr1d2	Pattern Name Modisco Significance metacluster_1/pattern_13 0.00798777
Rorc	Pattern Name Modisco Significance metacluster_1/pattern_13 0.023193000000000002
Nr1d1	Pattern Name Modisco Significance metacluster_1/pattern_13 0.042746
Nfatc1	Pattern Name Modisco Significance metacluster_1/pattern_13 0.042746
Mef2d	Pattern Name Modisco Significance metacluster_1/pattern_14 7.94064e-11
Mef2c	Pattern Name Modisco Significance metacluster_1/pattern_14 2.3940000000000002e-09
Mef2a	Pattern Name Modisco Significance metacluster_1/pattern_14 0.00043209300000000004
Taf1	Pattern Name Modisco Significance metacluster_1/pattern_15 7.66053e-06
Yy1	Pattern Name Modisco Significance metacluster_1/pattern_15 7.66053e-06
Zfp42	Pattern Name Modisco Significance metacluster_1/pattern_15 0.0118262
Rfx1	Pattern Name Modisco Significance metacluster_1/pattern_15 0.012349899999999999 metacluster_1/pattern_16 9.92628e-08
Wt1	Pattern Name Modisco Significance metacluster_1/pattern_15 0.017417
Rfx2	Pattern Name Modisco Significance metacluster_1/pattern_16 0.028394799999999998
Rfx3	Pattern Name Modisco Significance metacluster_1/pattern_16 0.00107123
Rfx4	Pattern Name Modisco Significance metacluster_1/pattern_16 4.24803e-05
Rfx7	Pattern Name Modisco Significance metacluster_1/pattern_16 0.000526916
Rfx6	Pattern Name Modisco Significance metacluster_1/pattern_16 0.00025409099999999996
Sox2	Pattern Name Modisco Significance metacluster_1/pattern_16 0.0495025
Runx1	Pattern Name Modisco Significance metacluster_1/pattern_17 0.00539473 metacluster_1/pattern_18 0.00294625
Runx2	Pattern Name Modisco Significance metacluster_1/pattern_17 0.0278893 metacluster_1/pattern_18 0.00158821
Cbfb	Pattern Name Modisco Significance metacluster_1/pattern_17 0.00144051 metacluster_1/pattern_18 0.00456477
Runx3	Pattern Name Modisco Significance metacluster_1/pattern_17 0.0225185 metacluster_1/pattern_18 0.0366288
Nfia	Pattern Name Modisco Significance metacluster_1/pattern_19 1.14931e-05
Zbtb33	Pattern Name Modisco Significance metacluster_1/pattern_22 1.37486e-07

display_paiwise_pattern_comparison(data_name, modisco_root, homer_root)

Number of CISBP TFs obtained by TF-MoDISco and Homer

Shared TFs between TF-MoDISco and Homer: #113

TF Name	Modisco	Homer
Mitf	Pattern Name Modisco Significance metacluster_1/pattern_6 0.0116726	Pattern Name Homer Significance motif6.motif 0.00381072
Npas2	Pattern Name Modisco Significance metacluster_1/pattern_6 0.0120418	Pattern Name Homer Significance motif6.motif 0.00109715
Elk1	Pattern Name Modisco Significance metacluster_1/pattern_12 0.00418695	Pattern Name Homer Significance motif1.motif 0.021468599999999997
Klf7	Pattern Name Modisco Significance metacluster_1/pattern_4 0.000403571	Pattern Name Homer Significance motif4.motif 0.000118905
Mef2a	Pattern Name Modisco Significance metacluster_1/pattern_14 0.00043209300000000004	Pattern Name Homer Significance motif18.motif 0.000376064
Srebf1	Pattern Name Modisco Significance metacluster_1/pattern_6 0.0068334	Pattern Name Homer Significance motif6.motif 0.00465811
Elf1	Pattern Name Modisco Significance metacluster_1/pattern_12 0.00181956	Pattern Name Homer Significance motif1.motif 0.0380806
Klf5	Pattern Name Modisco Significance metacluster_1/pattern_4 0.018576699999999998	Pattern Name Homer Significance motif4.motif 0.00625162
Etv6	Pattern Name Modisco Significance metacluster_1/pattern_0 0.0501549 metacluster_1/pattern_12 0.029810000000000003 metacluster_1/pattern_13 0.023193000000000002	Pattern Name Homer Significance motif1.motif 0.024378
Sp5	Pattern Name Modisco Significance metacluster_1/pattern_4 0.0187459	Pattern Name Homer Significance motif4.motif 0.0218393
Irf8	Pattern Name Modisco Significance metacluster_1/pattern_0 3.9634300000000004e-07 metacluster_1/pattern_3 3.77672e-15	Pattern Name Homer Significance motif1.motif 4.85947e-09
Creb5	Pattern Name Modisco Significance metacluster_1/pattern_7 0.000441931	Pattern Name Homer Significance motif6.motif 0.0352913
E2f1	Pattern Name Modisco Significance metacluster_1/pattern_4 0.0161377	Pattern Name Homer Significance motif4.motif 0.00606308
Irf3	Pattern Name Modisco Significance metacluster_1/pattern_0 0.0104884 metacluster_1/pattern_3 0.000681744	Pattern Name Homer Significance motif1.motif 0.00661858
Jdp2	Pattern Name Modisco Significance metacluster_1/pattern_2 0.000407175 metacluster_1/pattern_7 0.00168716 metacluster_1/pattern_13 0.0388971	Pattern Name Homer Significance motif3.motif 0.000656127 motif6.motif 0.0352913 motif7.motif 0.021690900000000003
Ctcfl	Pattern Name Modisco Significance metacluster_1/pattern_1 3.86141e-07	Pattern Name Homer Significance motif2.motif 0.000905566
Batf	Pattern Name Modisco Significance metacluster_1/pattern_2 0.0190062 metacluster_1/pattern_13 0.042746	Pattern Name Homer Significance motif3.motif 5.33401e-05
Bhlhe41	Pattern Name Modisco Significance metacluster_1/pattern_6 0.04132519999999999	Pattern Name Homer Significance motif6.motif 0.00486866
Erg	Pattern Name Modisco Significance metacluster_1/pattern_12 0.0115254 metacluster_1/pattern_13 0.0388971	Pattern Name Homer Significance motif1.motif 0.021468599999999997
Jund	Pattern Name Modisco Significance metacluster_1/pattern_2 0.009759499999999999 metacluster_1/pattern_13 0.0598125	Pattern Name Homer Significance motif3.motif 0.0211252
Atf4	Pattern Name Modisco Significance metacluster_1/pattern_5 0.0230418	Pattern Name Homer Significance motif7.motif 0.027051599999999995
Etv2	Pattern Name Modisco Significance metacluster_1/pattern_0 0.00958651 metacluster_1/pattern_12 0.042360300000000004	Pattern Name Homer Significance motif1.motif 0.00368454
Elf4	Pattern Name Modisco Significance metacluster_1/pattern_0 0.0580664 metacluster_1/pattern_12 0.029810000000000003	Pattern Name Homer Significance motif1.motif 0.0236002
Junb	Pattern Name Modisco Significance metacluster_1/pattern_2 0.030732599999999995 metacluster_1/pattern_13 0.023193000000000002	Pattern Name Homer Significance motif3.motif 0.0557779
Etv4	Pattern Name Modisco Significance metacluster_1/pattern_0 0.021223500000000003 metacluster_1/pattern_12 0.018215900000000004 metacluster_1/pattern_13 0.0263301	Pattern Name Homer Significance motif1.motif 0.0534211
Creb3l2	Pattern Name Modisco Significance metacluster_1/pattern_6 0.053600800000000004	Pattern Name Homer Significance motif6.motif 0.0352913
Maff	Pattern Name Modisco Significance metacluster_1/pattern_2 0.0297733	Pattern Name Homer Significance motif3.motif 0.00260117
Nrf1	Pattern Name Modisco Significance metacluster_1/pattern_8 4.925899999999999e-07	Pattern Name Homer Significance motif12.motif 4.84606e-07
Klf1	Pattern Name Modisco Significance metacluster_1/pattern_4 0.0332293	Pattern Name Homer Significance motif4.motif 0.026062000000000002
Elf3	Pattern Name Modisco Significance metacluster_1/pattern_0 0.0580664	Pattern Name Homer Significance motif1.motif 0.028714
Irf1	Pattern Name Modisco Significance metacluster_1/pattern_0 0.024373699999999998 metacluster_1/pattern_3 1.02706e-05	Pattern Name Homer Significance motif1.motif 0.0250834
Tbx2	Pattern Name Modisco Significance metacluster_1/pattern_10 4.29228e-14	Pattern Name Homer Significance motif5.motif 9.95074e-05
Spi1	Pattern Name Modisco Significance metacluster_1/pattern_0 0.00303171 metacluster_1/pattern_3 0.008117000000000001 metacluster_1/pattern_11 0.00891111 metacluster_1/pattern_13 0.0388971	Pattern Name Homer Significance motif1.motif 0.00264434
Elk4	Pattern Name Modisco Significance metacluster_1/pattern_12 0.00437295	Pattern Name Homer Significance motif1.motif 0.0344824
Usf1	Pattern Name Modisco Significance metacluster_1/pattern_6 0.0254166	Pattern Name Homer Significance motif6.motif 0.00440191
Etv5	Pattern Name Modisco Significance metacluster_1/pattern_12 0.00382864	Pattern Name Homer Significance motif1.motif 0.0534211
Sp3	Pattern Name Modisco Significance metacluster_1/pattern_4 9.4455e-06 metacluster_1/pattern_15 0.00230657 metacluster_1/pattern_22 0.0210026	Pattern Name Homer Significance motif4.motif 0.000118905
Nfe2	Pattern Name Modisco Significance metacluster_1/pattern_2 0.0117015	Pattern Name Homer Significance motif3.motif 0.00456125
Atf2	Pattern Name Modisco Significance metacluster_1/pattern_7 0.00117127	Pattern Name Homer Significance motif6.motif 0.0378425 motif7.motif 0.0287393
Cebpg	Pattern Name Modisco Significance metacluster_1/pattern_5 0.0170536	Pattern Name Homer Significance motif7.motif 0.0199293
Dbp	Pattern Name Modisco Significance metacluster_1/pattern_5 0.0560054	Pattern Name Homer Significance motif7.motif 0.00204127
Tfeb	Pattern Name Modisco Significance metacluster_1/pattern_6 0.00993503	Pattern Name Homer Significance motif6.motif 0.00109715
Klf8	Pattern Name Modisco Significance metacluster_1/pattern_4 0.000626525	Pattern Name Homer Significance motif4.motif 0.00017992599999999998
Etv3	Pattern Name Modisco Significance metacluster_1/pattern_0 0.0580664 metacluster_1/pattern_12 0.029567400000000004	Pattern Name Homer Significance motif1.motif 0.0205183
Arntl	Pattern Name Modisco Significance metacluster_1/pattern_6 0.028758299999999997	Pattern Name Homer Significance motif6.motif 0.00287187
Hlf	Pattern Name Modisco Significance metacluster_1/pattern_5 0.00319918	Pattern Name Homer Significance motif7.motif 0.00443615
Bach1	Pattern Name Modisco Significance metacluster_1/pattern_2 0.0117015	Pattern Name Homer Significance motif3.motif 0.00966214
Cebpd	Pattern Name Modisco Significance metacluster_1/pattern_5 0.00999219	Pattern Name Homer Significance motif7.motif 0.000556371
Prdm1	Pattern Name Modisco Significance metacluster_1/pattern_0 0.00958651 metacluster_1/pattern_3 0.00386173	Pattern Name Homer Significance motif1.motif 0.015419299999999999
Zfp42	Pattern Name Modisco Significance metacluster_1/pattern_15 0.0118262	Pattern Name Homer Significance motif13.motif 0.00930373
Fli1	Pattern Name Modisco Significance metacluster_1/pattern_12 0.0115254 metacluster_1/pattern_13 0.0388971	Pattern Name Homer Significance motif1.motif 0.0213679
Irf2	Pattern Name Modisco Significance metacluster_1/pattern_0 0.024373699999999998 metacluster_1/pattern_3 0.0113699	Pattern Name Homer Significance motif1.motif 0.021468599999999997
E2f4	Pattern Name Modisco Significance metacluster_1/pattern_4 0.000403571	Pattern Name Homer Significance motif4.motif 0.000945537
Maf	Pattern Name Modisco Significance metacluster_1/pattern_2 0.0296281	Pattern Name Homer Significance motif3.motif 0.00404352
Cebpa	Pattern Name Modisco Significance metacluster_1/pattern_5 0.00763158 metacluster_1/pattern_7 0.0586466	Pattern Name Homer Significance motif7.motif 0.000109517
Ehf	Pattern Name Modisco Significance metacluster_1/pattern_0 0.021223500000000003 metacluster_1/pattern_12 0.0242813	Pattern Name Homer Significance motif1.motif 0.0550177
Thap11	Pattern Name Modisco Significance metacluster_1/pattern_10 4.6510200000000004e-21	Pattern Name Homer Significance motif5.motif 8.08383e-07
Mlx	Pattern Name Modisco Significance metacluster_1/pattern_6 0.0383926	Pattern Name Homer Significance motif6.motif 0.00486866
Elf5	Pattern Name Modisco Significance metacluster_1/pattern_0 0.0387776 metacluster_1/pattern_12 0.0314308	Pattern Name Homer Significance motif1.motif 0.038185500000000004
Taf1	Pattern Name Modisco Significance metacluster_1/pattern_15 7.66053e-06	Pattern Name Homer Significance motif13.motif 2.44017e-05
Tfec	Pattern Name Modisco Significance metacluster_1/pattern_6 0.0141007	Pattern Name Homer Significance motif6.motif 0.00109715
XP_911724.4	Pattern Name Modisco Significance metacluster_1/pattern_12 0.0368601	Pattern Name Homer Significance motif1.motif 0.021468599999999997
Sp4	Pattern Name Modisco Significance metacluster_1/pattern_4 0.00131222 metacluster_1/pattern_15 0.0554783	Pattern Name Homer Significance motif4.motif 0.00625162
Atf1	Pattern Name Modisco Significance metacluster_1/pattern_7 0.0319505	Pattern Name Homer Significance motif6.motif 0.019933799999999998
Mafg	Pattern Name Modisco Significance metacluster_1/pattern_2 0.021782	Pattern Name Homer Significance motif3.motif 0.00213735
Mafb	Pattern Name Modisco Significance metacluster_1/pattern_2 0.021782	Pattern Name Homer Significance motif3.motif 0.00865364
Fosl1	Pattern Name Modisco Significance metacluster_1/pattern_2 0.009759499999999999	Pattern Name Homer Significance motif3.motif 0.0280289
Zfp143	Pattern Name Modisco Significance metacluster_1/pattern_10 1.63313e-20	Pattern Name Homer Significance motif5.motif 2.34771e-06
Irf4	Pattern Name Modisco Significance metacluster_1/pattern_0 5.28371e-06 metacluster_1/pattern_3 0.0326039 metacluster_1/pattern_13 0.023193000000000002	Pattern Name Homer Significance motif1.motif 1.61245e-07
Creb1	Pattern Name Modisco Significance metacluster_1/pattern_7 0.0201107	Pattern Name Homer Significance motif6.motif 0.0352913
Mef2c	Pattern Name Modisco Significance metacluster_1/pattern_14 2.3940000000000002e-09	Pattern Name Homer Significance motif18.motif 0.000658382
Jun	Pattern Name Modisco Significance metacluster_1/pattern_2 0.047782599999999995 metacluster_1/pattern_7 0.046176999999999996 metacluster_1/pattern_13 0.023193000000000002	Pattern Name Homer Significance motif3.motif 3.36391e-05
Mafk	Pattern Name Modisco Significance metacluster_1/pattern_2 0.009759499999999999	Pattern Name Homer Significance motif3.motif 0.00162569
Usf2	Pattern Name Modisco Significance metacluster_1/pattern_6 0.0194168 metacluster_1/pattern_12 0.039552199999999996	Pattern Name Homer Significance motif6.motif 0.00270027 motif16.motif 0.028991500000000003
Zbtb17	Pattern Name Modisco Significance metacluster_1/pattern_4 0.00944787 metacluster_1/pattern_12 0.039552199999999996 metacluster_1/pattern_15 0.0118262 metacluster_1/pattern_22 0.051789699999999994	Pattern Name Homer Significance motif4.motif 0.00566159
Arnt	Pattern Name Modisco Significance metacluster_1/pattern_6 0.0425872	Pattern Name Homer Significance motif6.motif 0.0382702
Ctcf	Pattern Name Modisco Significance metacluster_1/pattern_1 2.00493e-15	Pattern Name Homer Significance motif2.motif 0.00046181900000000003
Ets1	Pattern Name Modisco Significance metacluster_1/pattern_0 0.0580664 metacluster_1/pattern_12 0.0115254	Pattern Name Homer Significance motif1.motif 0.018053200000000002
Nfil3	Pattern Name Modisco Significance metacluster_1/pattern_5 0.00337946 metacluster_1/pattern_7 0.04674280000000001	Pattern Name Homer Significance motif7.motif 0.0115333
Sp2	Pattern Name Modisco Significance metacluster_1/pattern_4 6.348049999999999e-06 metacluster_1/pattern_15 0.000196708 metacluster_1/pattern_22 0.00459682	Pattern Name Homer Significance motif4.motif 0.000142048
Nfe2l2	Pattern Name Modisco Significance metacluster_1/pattern_2 0.013099000000000001	Pattern Name Homer Significance motif3.motif 0.00478157
Tfe3	Pattern Name Modisco Significance metacluster_1/pattern_6 0.0165978	Pattern Name Homer Significance motif6.motif 0.00109715
Mef2d	Pattern Name Modisco Significance metacluster_1/pattern_14 7.94064e-11	Pattern Name Homer Significance motif18.motif 0.000264419
Klf12	Pattern Name Modisco Significance metacluster_1/pattern_4 0.00861131	Pattern Name Homer Significance motif4.motif 0.013132099999999999
Srebf2	Pattern Name Modisco Significance metacluster_1/pattern_6 0.0166616	Pattern Name Homer Significance motif6.motif 0.0169815
Fos	Pattern Name Modisco Significance metacluster_1/pattern_2 4.64369e-07	Pattern Name Homer Significance motif3.motif 1.1934299999999999e-06
Spic	Pattern Name Modisco Significance metacluster_1/pattern_0 0.00486297 metacluster_1/pattern_11 0.00206876	Pattern Name Homer Significance motif1.motif 0.00031793
Elf2	Pattern Name Modisco Significance metacluster_1/pattern_0 0.0580664 metacluster_1/pattern_12 0.035716000000000005 metacluster_1/pattern_13 0.023193000000000002	Pattern Name Homer Significance motif1.motif 0.0273358
Cebpe	Pattern Name Modisco Significance metacluster_1/pattern_5 0.0140874	Pattern Name Homer Significance motif7.motif 0.0009075719999999999
Klf3	Pattern Name Modisco Significance metacluster_1/pattern_4 6.348049999999999e-06 metacluster_1/pattern_15 0.0554783	Pattern Name Homer Significance motif4.motif 0.000118905
Spib	Pattern Name Modisco Significance metacluster_1/pattern_0 4.08549e-11 metacluster_1/pattern_3 8.608e-07 metacluster_1/pattern_13 0.023193000000000002	Pattern Name Homer Significance motif1.motif 8.92479e-08
Zbtb1	Pattern Name Modisco Significance metacluster_1/pattern_4 0.05775790000000001	Pattern Name Homer Significance motif4.motif 0.0195291
Tcfl5	Pattern Name Modisco Significance metacluster_1/pattern_6 0.025986099999999998	Pattern Name Homer Significance motif6.motif 0.0352913
Egr2	Pattern Name Modisco Significance metacluster_1/pattern_4 0.033326 metacluster_1/pattern_15 0.0260923	Pattern Name Homer Significance motif4.motif 0.0274207
Mafa	Pattern Name Modisco Significance metacluster_1/pattern_2 0.00681553	Pattern Name Homer Significance motif3.motif 0.00404352
Bhlhe40	Pattern Name Modisco Significance metacluster_1/pattern_6 0.0252379	Pattern Name Homer Significance motif6.motif 0.017928
Egr1	Pattern Name Modisco Significance metacluster_1/pattern_4 0.0302502	Pattern Name Homer Significance motif4.motif 0.0257955
Klf4	Pattern Name Modisco Significance metacluster_1/pattern_4 0.00861131	Pattern Name Homer Significance motif4.motif 0.014823099999999999
Bach2	Pattern Name Modisco Significance metacluster_1/pattern_2 0.00518615	Pattern Name Homer Significance motif3.motif 0.000957647
Tef	Pattern Name Modisco Significance metacluster_1/pattern_5 0.0357772	Pattern Name Homer Significance motif7.motif 0.000611502
Fosb	Pattern Name Modisco Significance metacluster_1/pattern_2 0.00028498900000000003 metacluster_1/pattern_13 0.023193000000000002	Pattern Name Homer Significance motif3.motif 0.000312114
Elk3	Pattern Name Modisco Significance metacluster_1/pattern_12 0.00236884	Pattern Name Homer Significance motif1.motif 0.042335000000000005
Yy1	Pattern Name Modisco Significance metacluster_1/pattern_15 7.66053e-06	Pattern Name Homer Significance motif13.motif 0.00037183699999999997
Fosl2	Pattern Name Modisco Significance metacluster_1/pattern_2 0.050574 metacluster_1/pattern_7 0.0201107 metacluster_1/pattern_13 0.0598125	Pattern Name Homer Significance motif3.motif 1.1934299999999999e-06
Cebpb	Pattern Name Modisco Significance metacluster_1/pattern_5 0.00714947	Pattern Name Homer Significance motif7.motif 4.71162e-05
Crem	Pattern Name Modisco Significance metacluster_1/pattern_7 0.0130111	Pattern Name Homer Significance motif6.motif 0.0352913
Clock	Pattern Name Modisco Significance metacluster_1/pattern_6 0.00561913	Pattern Name Homer Significance motif6.motif 0.00135512
Atf3	Pattern Name Modisco Significance metacluster_1/pattern_2 0.000327321 metacluster_1/pattern_7 0.00479348 metacluster_1/pattern_13 0.023193000000000002	Pattern Name Homer Significance motif3.motif 0.000312114 motif6.motif 0.0417656
Etv1	Pattern Name Modisco Significance metacluster_1/pattern_12 0.00567679	Pattern Name Homer Significance motif1.motif 0.0580067
Gabpa	Pattern Name Modisco Significance metacluster_1/pattern_12 0.00418695	Pattern Name Homer Significance motif1.motif 0.058708
Atf7	Pattern Name Modisco Significance metacluster_1/pattern_7 0.000383137	Pattern Name Homer Significance motif6.motif 0.0578857 motif7.motif 0.0218706
Klf6	Pattern Name Modisco Significance metacluster_1/pattern_4 0.000403571	Pattern Name Homer Significance motif4.motif 0.00107881
Sp1	Pattern Name Modisco Significance metacluster_1/pattern_4 0.000456535 metacluster_1/pattern_15 0.000248553 metacluster_1/pattern_22 0.00861558	Pattern Name Homer Significance motif4.motif 0.00533096

Unique TF-MoDISco TFs: #34

TF Name	Modisco	Homer
Fev	Pattern Name Modisco Significance metacluster_1/pattern_12 0.00437295	Absent
Irf9	Pattern Name Modisco Significance metacluster_1/pattern_3 0.0113699	Absent
Stat2	Pattern Name Modisco Significance metacluster_1/pattern_3 0.00368333	Absent
Zfp281	Pattern Name Modisco Significance metacluster_1/pattern_4 0.033326	Absent
Sox2	Pattern Name Modisco Significance metacluster_1/pattern_16 0.0495025	Absent
Cbfb	Pattern Name Modisco Significance metacluster_1/pattern_17 0.00144051 metacluster_1/pattern_18 0.00456477	Absent
Rfx4	Pattern Name Modisco Significance metacluster_1/pattern_16 4.24803e-05	Absent
Nfyb	Pattern Name Modisco Significance metacluster_1/pattern_9 3.59726e-08	Absent
Runx3	Pattern Name Modisco Significance metacluster_1/pattern_17 0.0225185 metacluster_1/pattern_18 0.0366288	Absent
Runx2	Pattern Name Modisco Significance metacluster_1/pattern_17 0.0278893 metacluster_1/pattern_18 0.00158821	Absent
Rfx3	Pattern Name Modisco Significance metacluster_1/pattern_16 0.00107123	Absent
Zscan10	Pattern Name Modisco Significance metacluster_1/pattern_3 0.00861557	Absent
Zfx	Pattern Name Modisco Significance metacluster_1/pattern_4 0.05484580000000001 metacluster_1/pattern_15 0.00433036 metacluster_1/pattern_22 0.035924300000000006	Absent
Nfia	Pattern Name Modisco Significance metacluster_1/pattern_19 1.14931e-05	Absent
Egr3	Pattern Name Modisco Significance metacluster_1/pattern_4 0.041667199999999995	Absent
Nfatc1	Pattern Name Modisco Significance metacluster_1/pattern_13 0.042746	Absent
Rfx7	Pattern Name Modisco Significance metacluster_1/pattern_16 0.000526916	Absent
Rorc	Pattern Name Modisco Significance metacluster_1/pattern_13 0.023193000000000002	Absent
Zfp740	Pattern Name Modisco Significance metacluster_1/pattern_4 0.040631400000000005	Absent
Stat1	Pattern Name Modisco Significance metacluster_1/pattern_3 0.00577965	Absent
Nfya	Pattern Name Modisco Significance metacluster_1/pattern_9 3.59726e-08	Absent
Pbx3	Pattern Name Modisco Significance metacluster_1/pattern_9 9.89e-06	Absent
Nfyc	Pattern Name Modisco Significance metacluster_1/pattern_9 3.59726e-08	Absent
Rfx2	Pattern Name Modisco Significance metacluster_1/pattern_16 0.028394799999999998	Absent
Rfx1	Pattern Name Modisco Significance metacluster_1/pattern_15 0.012349899999999999 metacluster_1/pattern_16 9.92628e-08	Absent
Nr1d1	Pattern Name Modisco Significance metacluster_1/pattern_13 0.042746	Absent
Zbtb33	Pattern Name Modisco Significance metacluster_1/pattern_22 1.37486e-07	Absent
Ddit3	Pattern Name Modisco Significance metacluster_1/pattern_5 0.014235499999999998	Absent
Runx1	Pattern Name Modisco Significance metacluster_1/pattern_17 0.00539473 metacluster_1/pattern_18 0.00294625	Absent
Foxi1	Pattern Name Modisco Significance metacluster_1/pattern_9 4.44778e-06	Absent
Wt1	Pattern Name Modisco Significance metacluster_1/pattern_15 0.017417	Absent
Rfx6	Pattern Name Modisco Significance metacluster_1/pattern_16 0.00025409099999999996	Absent
Nr1d2	Pattern Name Modisco Significance metacluster_1/pattern_13 0.00798777	Absent
Irf7	Pattern Name Modisco Significance metacluster_1/pattern_3 0.004683	Absent

Unique Homer TFs: #11

TF Name	Modisco	Homer
Mlxip	Absent	Pattern Name Homer Significance motif6.motif 0.054835300000000003
Mycn	Absent	Pattern Name Homer Significance motif6.motif 0.0417656
Max	Absent	Pattern Name Homer Significance motif6.motif 0.0578857
E2f7	Absent	Pattern Name Homer Significance motif4.motif 0.014823099999999999
Klf15	Absent	Pattern Name Homer Significance motif4.motif 0.00533405
Xbp1	Absent	Pattern Name Homer Significance motif6.motif 0.0147644
Myc	Absent	Pattern Name Homer Significance motif6.motif 0.0553403
Mypop	Absent	Pattern Name Homer Significance motif7.motif 0.0537601
Bcl6	Absent	Pattern Name Homer Significance motif1.motif 0.028714
E2f6	Absent	Pattern Name Homer Significance motif4.motif 0.056587599999999995
Hey2	Absent	Pattern Name Homer Significance motif6.motif 0.0363384