# Parameters
data_name = "CD4+CD8-TCR+CD69-CD24-CD25-;B2defM;A;CL"
modisco_root = "/srv/scratch/msharmin/mouse_hem/with_tfd/full_mouse50/Naive_modisco2019"
tomtom_report_root = "http://mitra.stanford.edu/kundaje/msharmin/report/tomtom_outs/cells"
task_dir = "task_36-naivegw"
perf_file = "/srv/scratch/msharmin/mouse_hem/with_tfd/full_mouse50/fineFactorized/task_36-naivegw/NaiveauPRC.txt"
homer_root = "/srv/scratch/msharmin/mouse_hem/with_tfd/full_mouse50/Naive_scans"
reportfile = "/mnt/lab_data/kundaje/msharmin/annotations/filtering samples_MS2.xlsx"
sheetname = "filter23"

from matlas.reports import display_metadata

load data from labcluster

Using TensorFlow backend.
2019-08-30 18:47:59,166 [WARNING] git-lfs not installed

display_metadata(data_name, perf_file, reportfile, sheetname)

Sample Information

MetaData Name	Description
Cell type	CD4+CD8-TCRhi CD69lo CD24lo CD25- (B2m def mice)
Cell Group	T cells
Experiment Name	ATAC
Experiment Group	Casellas Lab

Pipeline Output

replicate	Naïve overlap peaks	IDR peaks	TSS enrichment (< 8 is very poor <10 is low)	Final number of unique mapping, dup-filtered, chrM filtered reads	Number of reads in called peak regions	Fraction of reads in called peak regions	Number of reads in promoter regions	Fraction of reads in promoter regions	Number of reads in enhancer regions	Fraction of reads in enhancer regions
rep1	106135	85197	12.9989	46290913	8795035	0.1901	5835900	0.1261	15900853	0.3436

Modelling Metadata

Metric	Value
auPRC	0.5791
Calibrated Recall at 50% FDR	0.213
Number of Positive Examples in Test Data	89237
Number of Negative Examples in Test Data	7981614
Imbalance Ratio in Test Data	0.0111
Test Chromosomes	chr2, chr3, chr19

from matlas.reports import display_paiwise_pattern_comparison
from matlas.reports import display_denovo_patterns

display_denovo_patterns(data_name, modisco_root=modisco_root)

TF-MoDISco is using the TensorFlow backend.

The following two links show list of Denovo Patterns and corresponding Motifs discovered by TF-MoDISco

Click here for Denovo Patterns by TF-MoDISco: #20

Pattern Name	TF Name(s)	Modisco
metacluster_1/pattern_0 # seqlets: 5827 SequenceContrib ScoresHyp_Contrib Scores	Erg, Ets1, Fli1, Etv2, Elk4, Etv4, Elk1, Gabpa, Etv5, Elk3, Fev, Spi1, Etv6, Etv3, XP_911724.4, Etv1, Elf2, Elf1, Elf4, Spib, Ehf, Elf5, Elf3, Spdef, Irf8, Spic, Irf4, Stat3, Stat4, Zscan10
metacluster_1/pattern_1 # seqlets: 4941 SequenceContrib ScoresHyp_Contrib Scores	Sp2, Sp4, Sp3, Klf3, Sp1, E2f4, Klf4, Klf6, Klf7, Klf8, Klf1, Klf12, Egr1, Zbtb17, Egr2, E2f1, Klf5, Zfp281, Sp5, Zfx, Zfp740, Egr3, Sall4, Zbtb1
metacluster_1/pattern_2 # seqlets: 3742 SequenceContrib ScoresHyp_Contrib Scores	Ctcf, Ctcfl
metacluster_1/pattern_3 # seqlets: 1363 SequenceContrib ScoresHyp_Contrib Scores	Nrf1
metacluster_1/pattern_4 # seqlets: 1336 SequenceContrib ScoresHyp_Contrib Scores	Nfyb, Nfyc, Nfya, Foxi1, Pbx3
metacluster_1/pattern_5 # seqlets: 1162 SequenceContrib ScoresHyp_Contrib Scores	Irf1, Irf2, Prdm1, Stat1, Irf7, Irf3, Irf9, Stat2, Batf3
metacluster_1/pattern_6 # seqlets: 882 SequenceContrib ScoresHyp_Contrib Scores	Runx1, Runx2, Runx3, Cbfb
metacluster_1/pattern_7 # seqlets: 836 SequenceContrib ScoresHyp_Contrib Scores
metacluster_1/pattern_8 # seqlets: 785 SequenceContrib ScoresHyp_Contrib Scores	Taf1, Yy1, Rfx1, Zfp42, Mxi1, Usf2
metacluster_1/pattern_9 # seqlets: 674 SequenceContrib ScoresHyp_Contrib Scores	Usf1, Tfec, Tfe3, Tfeb, Arntl, Mitf, Srebf1, Bhlhe40, Clock, Mlx, Arnt, Srebf2, Npas2, Tcfl5, Creb3l2, Mycn, Max, Bhlhe41, Creb1, Atf1, Atf7, Hlf, Myc, Jdp2, Atf2, Dbp, Xbp1, Mlxip
metacluster_1/pattern_10 # seqlets: 657 SequenceContrib ScoresHyp_Contrib Scores	Zfp143, Thap11, Tbx2
metacluster_1/pattern_11 # seqlets: 588 SequenceContrib ScoresHyp_Contrib Scores	Tcf7l2, Lef1, Tcf3, Tcf7l1, Tcf7
metacluster_1/pattern_12 # seqlets: 557 SequenceContrib ScoresHyp_Contrib Scores	Crem, Creb5, Atf3, Fosl2, Nfil3, Jun, Tef
metacluster_1/pattern_13 # seqlets: 279 SequenceContrib ScoresHyp_Contrib Scores	Rfx3, Rfx2, Rfx4, Rfx7, Rfx6
metacluster_1/pattern_14 # seqlets: 237 SequenceContrib ScoresHyp_Contrib Scores	Ets2
metacluster_1/pattern_15 # seqlets: 144 SequenceContrib ScoresHyp_Contrib Scores	Zbtb33
metacluster_1/pattern_16 # seqlets: 130 SequenceContrib ScoresHyp_Contrib Scores	Nfkb2, Nfkb1, Rela, Relb, Rel
metacluster_1/pattern_17 # seqlets: 110 SequenceContrib ScoresHyp_Contrib Scores	Nfib, Nfia, Nfic
metacluster_1/pattern_18 # seqlets: 95 SequenceContrib ScoresHyp_Contrib Scores	Mef2a, Mef2c, Mef2d
metacluster_1/pattern_19 # seqlets: 50 SequenceContrib ScoresHyp_Contrib Scores

Click here for Motifs by TF-MoDISco: #142

TF Name	Pattern(s)
Erg	Pattern Name Modisco Significance metacluster_1/pattern_0 0.000991736 metacluster_1/pattern_14 0.042299800000000005
Ets1	Pattern Name Modisco Significance metacluster_1/pattern_0 0.000991736 metacluster_1/pattern_7 0.0443844 metacluster_1/pattern_14 0.0115288
Fli1	Pattern Name Modisco Significance metacluster_1/pattern_0 0.00101768 metacluster_1/pattern_14 0.042299800000000005
Etv2	Pattern Name Modisco Significance metacluster_1/pattern_0 2.45437e-05 metacluster_1/pattern_14 0.0115288
Elk4	Pattern Name Modisco Significance metacluster_1/pattern_0 0.00107283 metacluster_1/pattern_14 0.0599438
Etv4	Pattern Name Modisco Significance metacluster_1/pattern_0 0.0010647999999999999
Elk1	Pattern Name Modisco Significance metacluster_1/pattern_0 0.00107283
Gabpa	Pattern Name Modisco Significance metacluster_1/pattern_0 0.0010647999999999999
Etv5	Pattern Name Modisco Significance metacluster_1/pattern_0 0.00035459699999999995
Elk3	Pattern Name Modisco Significance metacluster_1/pattern_0 0.0010647999999999999
Fev	Pattern Name Modisco Significance metacluster_1/pattern_0 0.000783408
Spi1	Pattern Name Modisco Significance metacluster_1/pattern_0 0.051172 metacluster_1/pattern_14 0.0534962
Etv6	Pattern Name Modisco Significance metacluster_1/pattern_0 0.000964335 metacluster_1/pattern_14 0.0314718
Etv3	Pattern Name Modisco Significance metacluster_1/pattern_0 0.0010647999999999999
XP_911724.4	Pattern Name Modisco Significance metacluster_1/pattern_0 0.0010647999999999999
Etv1	Pattern Name Modisco Significance metacluster_1/pattern_0 0.00121407
Elf2	Pattern Name Modisco Significance metacluster_1/pattern_0 0.00779534 metacluster_1/pattern_14 0.03932940000000001
Elf1	Pattern Name Modisco Significance metacluster_1/pattern_0 0.00262069
Elf4	Pattern Name Modisco Significance metacluster_1/pattern_0 0.00453066
Spib	Pattern Name Modisco Significance metacluster_1/pattern_0 0.00493136 metacluster_1/pattern_5 0.00274814
Ehf	Pattern Name Modisco Significance metacluster_1/pattern_0 0.00779534
Elf5	Pattern Name Modisco Significance metacluster_1/pattern_0 0.025013099999999996 metacluster_1/pattern_14 0.0314718
Elf3	Pattern Name Modisco Significance metacluster_1/pattern_0 0.021092700000000002 metacluster_1/pattern_14 0.042299800000000005
Spdef	Pattern Name Modisco Significance metacluster_1/pattern_0 0.018027
Irf8	Pattern Name Modisco Significance metacluster_1/pattern_0 0.0240158 metacluster_1/pattern_5 2.55128e-06
Spic	Pattern Name Modisco Significance metacluster_1/pattern_0 0.05955560000000001
Irf4	Pattern Name Modisco Significance metacluster_1/pattern_0 0.0255606 metacluster_1/pattern_5 0.0481705
Stat3	Pattern Name Modisco Significance metacluster_1/pattern_0 0.051172
Stat4	Pattern Name Modisco Significance metacluster_1/pattern_0 0.050425199999999996
Zscan10	Pattern Name Modisco Significance metacluster_1/pattern_0 0.050425199999999996
Sp2	Pattern Name Modisco Significance metacluster_1/pattern_1 4.35784e-06 metacluster_1/pattern_8 0.000126722 metacluster_1/pattern_12 0.00233514 metacluster_1/pattern_15 0.00285543
Sp4	Pattern Name Modisco Significance metacluster_1/pattern_1 0.00128071 metacluster_1/pattern_8 0.0508835
Sp3	Pattern Name Modisco Significance metacluster_1/pattern_1 5.9100300000000006e-06 metacluster_1/pattern_8 0.00482555 metacluster_1/pattern_12 0.043067900000000006 metacluster_1/pattern_15 0.00616209
Klf3	Pattern Name Modisco Significance metacluster_1/pattern_1 1.5641400000000002e-05 metacluster_1/pattern_8 0.057522699999999996
Sp1	Pattern Name Modisco Significance metacluster_1/pattern_1 0.00035822800000000004 metacluster_1/pattern_8 0.00482555 metacluster_1/pattern_12 0.00799383 metacluster_1/pattern_15 0.03302940000000001
E2f4	Pattern Name Modisco Significance metacluster_1/pattern_1 0.0004556
Klf4	Pattern Name Modisco Significance metacluster_1/pattern_1 0.00873906
Klf6	Pattern Name Modisco Significance metacluster_1/pattern_1 0.00047851699999999997
Klf7	Pattern Name Modisco Significance metacluster_1/pattern_1 0.00047851699999999997
Klf8	Pattern Name Modisco Significance metacluster_1/pattern_1 0.000680465
Klf1	Pattern Name Modisco Significance metacluster_1/pattern_1 0.031750099999999996
Klf12	Pattern Name Modisco Significance metacluster_1/pattern_1 0.0121331
Egr1	Pattern Name Modisco Significance metacluster_1/pattern_1 0.0421782
Zbtb17	Pattern Name Modisco Significance metacluster_1/pattern_1 0.00460312
Egr2	Pattern Name Modisco Significance metacluster_1/pattern_1 0.033979 metacluster_1/pattern_8 0.0508835
E2f1	Pattern Name Modisco Significance metacluster_1/pattern_1 0.00915582
Klf5	Pattern Name Modisco Significance metacluster_1/pattern_1 0.011325299999999998
Zfp281	Pattern Name Modisco Significance metacluster_1/pattern_1 0.0202285
Sp5	Pattern Name Modisco Significance metacluster_1/pattern_1 0.020424599999999998
Zfx	Pattern Name Modisco Significance metacluster_1/pattern_1 0.026437400000000003 metacluster_1/pattern_8 0.00373064 metacluster_1/pattern_12 0.0114432 metacluster_1/pattern_15 0.0011835
Zfp740	Pattern Name Modisco Significance metacluster_1/pattern_1 0.0421782
Egr3	Pattern Name Modisco Significance metacluster_1/pattern_1 0.0457559
Sall4	Pattern Name Modisco Significance metacluster_1/pattern_1 0.0523688
Zbtb1	Pattern Name Modisco Significance metacluster_1/pattern_1 0.0537304
Ctcf	Pattern Name Modisco Significance metacluster_1/pattern_2 5.735370000000001e-15
Ctcfl	Pattern Name Modisco Significance metacluster_1/pattern_2 6.25238e-08
Nrf1	Pattern Name Modisco Significance metacluster_1/pattern_3 2.23413e-09
Nfyb	Pattern Name Modisco Significance metacluster_1/pattern_4 7.226269999999999e-14
Nfyc	Pattern Name Modisco Significance metacluster_1/pattern_4 3.9074300000000006e-10
Nfya	Pattern Name Modisco Significance metacluster_1/pattern_4 1.1546700000000001e-08
Foxi1	Pattern Name Modisco Significance metacluster_1/pattern_4 3.1545799999999997e-06
Pbx3	Pattern Name Modisco Significance metacluster_1/pattern_4 4.79861e-06
Irf1	Pattern Name Modisco Significance metacluster_1/pattern_5 3.50134e-12
Irf2	Pattern Name Modisco Significance metacluster_1/pattern_5 0.00093268
Prdm1	Pattern Name Modisco Significance metacluster_1/pattern_5 0.000112859
Stat1	Pattern Name Modisco Significance metacluster_1/pattern_5 0.00012366700000000002
Irf7	Pattern Name Modisco Significance metacluster_1/pattern_5 0.000141117
Irf3	Pattern Name Modisco Significance metacluster_1/pattern_5 0.00183897
Irf9	Pattern Name Modisco Significance metacluster_1/pattern_5 0.00274814
Stat2	Pattern Name Modisco Significance metacluster_1/pattern_5 0.00316481
Batf3	Pattern Name Modisco Significance metacluster_1/pattern_5 0.0107084
Runx1	Pattern Name Modisco Significance metacluster_1/pattern_6 0.00121217
Runx2	Pattern Name Modisco Significance metacluster_1/pattern_6 0.00871647
Runx3	Pattern Name Modisco Significance metacluster_1/pattern_6 0.00365566
Cbfb	Pattern Name Modisco Significance metacluster_1/pattern_6 0.00535626
Taf1	Pattern Name Modisco Significance metacluster_1/pattern_8 3.2952300000000002e-06
Yy1	Pattern Name Modisco Significance metacluster_1/pattern_8 7.065130000000001e-06
Rfx1	Pattern Name Modisco Significance metacluster_1/pattern_8 0.012642 metacluster_1/pattern_12 0.026961400000000003 metacluster_1/pattern_13 3.69651e-10
Zfp42	Pattern Name Modisco Significance metacluster_1/pattern_8 0.012642
Mxi1	Pattern Name Modisco Significance metacluster_1/pattern_8 0.0508835
Usf2	Pattern Name Modisco Significance metacluster_1/pattern_8 0.051330799999999996 metacluster_1/pattern_9 0.00515726 metacluster_1/pattern_12 1.62125e-05
Usf1	Pattern Name Modisco Significance metacluster_1/pattern_9 0.00933855 metacluster_1/pattern_12 0.00583914
Tfec	Pattern Name Modisco Significance metacluster_1/pattern_9 0.00118041
Tfe3	Pattern Name Modisco Significance metacluster_1/pattern_9 0.00118041
Tfeb	Pattern Name Modisco Significance metacluster_1/pattern_9 0.000340158
Arntl	Pattern Name Modisco Significance metacluster_1/pattern_9 0.00903571
Mitf	Pattern Name Modisco Significance metacluster_1/pattern_9 0.0007131430000000001
Srebf1	Pattern Name Modisco Significance metacluster_1/pattern_9 0.028482900000000002
Bhlhe40	Pattern Name Modisco Significance metacluster_1/pattern_9 0.0074838000000000005
Clock	Pattern Name Modisco Significance metacluster_1/pattern_9 0.0276853
Mlx	Pattern Name Modisco Significance metacluster_1/pattern_9 0.00865515
Arnt	Pattern Name Modisco Significance metacluster_1/pattern_9 0.0471462
Srebf2	Pattern Name Modisco Significance metacluster_1/pattern_9 0.0034162 metacluster_1/pattern_12 0.0362792
Npas2	Pattern Name Modisco Significance metacluster_1/pattern_9 0.00429053
Tcfl5	Pattern Name Modisco Significance metacluster_1/pattern_9 0.00798086
Creb3l2	Pattern Name Modisco Significance metacluster_1/pattern_9 0.0209984
Mycn	Pattern Name Modisco Significance metacluster_1/pattern_9 0.011581399999999999
Max	Pattern Name Modisco Significance metacluster_1/pattern_9 0.0135347
Bhlhe41	Pattern Name Modisco Significance metacluster_1/pattern_9 0.0161567
Creb1	Pattern Name Modisco Significance metacluster_1/pattern_9 0.028482900000000002 metacluster_1/pattern_12 0.00233514
Atf1	Pattern Name Modisco Significance metacluster_1/pattern_9 0.018794599999999998 metacluster_1/pattern_12 0.0179243
Atf7	Pattern Name Modisco Significance metacluster_1/pattern_9 0.0199777 metacluster_1/pattern_12 0.000554584
Hlf	Pattern Name Modisco Significance metacluster_1/pattern_9 0.022927200000000002 metacluster_1/pattern_12 0.0276078
Myc	Pattern Name Modisco Significance metacluster_1/pattern_9 0.024591
Jdp2	Pattern Name Modisco Significance metacluster_1/pattern_9 0.0363905 metacluster_1/pattern_12 0.00103252
Atf2	Pattern Name Modisco Significance metacluster_1/pattern_9 0.041092699999999996 metacluster_1/pattern_12 0.00183645
Dbp	Pattern Name Modisco Significance metacluster_1/pattern_9 0.040766000000000004
Xbp1	Pattern Name Modisco Significance metacluster_1/pattern_9 0.0483735
Mlxip	Pattern Name Modisco Significance metacluster_1/pattern_9 0.058016
Zfp143	Pattern Name Modisco Significance metacluster_1/pattern_10 9.63309e-22
Thap11	Pattern Name Modisco Significance metacluster_1/pattern_10 4.44222e-21
Tbx2	Pattern Name Modisco Significance metacluster_1/pattern_10 8.78241e-14
Tcf7l2	Pattern Name Modisco Significance metacluster_1/pattern_11 3.56943e-05
Lef1	Pattern Name Modisco Significance metacluster_1/pattern_11 0.0317892
Tcf3	Pattern Name Modisco Significance metacluster_1/pattern_11 3.96961e-05
Tcf7l1	Pattern Name Modisco Significance metacluster_1/pattern_11 0.000713926
Tcf7	Pattern Name Modisco Significance metacluster_1/pattern_11 0.013709299999999999
Crem	Pattern Name Modisco Significance metacluster_1/pattern_12 0.0106932
Creb5	Pattern Name Modisco Significance metacluster_1/pattern_12 0.00103252
Atf3	Pattern Name Modisco Significance metacluster_1/pattern_12 0.0106932
Fosl2	Pattern Name Modisco Significance metacluster_1/pattern_12 0.013346100000000001
Nfil3	Pattern Name Modisco Significance metacluster_1/pattern_12 0.0354263
Jun	Pattern Name Modisco Significance metacluster_1/pattern_12 0.0420618
Tef	Pattern Name Modisco Significance metacluster_1/pattern_12 0.0514626
Rfx3	Pattern Name Modisco Significance metacluster_1/pattern_13 0.00105156
Rfx2	Pattern Name Modisco Significance metacluster_1/pattern_13 0.0421297
Rfx4	Pattern Name Modisco Significance metacluster_1/pattern_13 8.01275e-05
Rfx7	Pattern Name Modisco Significance metacluster_1/pattern_13 0.00060019
Rfx6	Pattern Name Modisco Significance metacluster_1/pattern_13 0.0008888930000000001
Ets2	Pattern Name Modisco Significance metacluster_1/pattern_14 0.0506171
Zbtb33	Pattern Name Modisco Significance metacluster_1/pattern_15 7.60047e-06
Nfkb2	Pattern Name Modisco Significance metacluster_1/pattern_16 7.26064e-05
Nfkb1	Pattern Name Modisco Significance metacluster_1/pattern_16 0.00021202
Rela	Pattern Name Modisco Significance metacluster_1/pattern_16 0.00122823
Relb	Pattern Name Modisco Significance metacluster_1/pattern_16 0.00276198
Rel	Pattern Name Modisco Significance metacluster_1/pattern_16 0.00869417
Nfib	Pattern Name Modisco Significance metacluster_1/pattern_17 1.6690400000000003e-06
Nfia	Pattern Name Modisco Significance metacluster_1/pattern_17 1.05522e-05
Nfic	Pattern Name Modisco Significance metacluster_1/pattern_17 0.00512136
Mef2a	Pattern Name Modisco Significance metacluster_1/pattern_18 5.01379e-05
Mef2c	Pattern Name Modisco Significance metacluster_1/pattern_18 2.5819599999999996e-09
Mef2d	Pattern Name Modisco Significance metacluster_1/pattern_18 2.5819599999999996e-09

display_paiwise_pattern_comparison(data_name, modisco_root, homer_root)

Number of CISBP TFs obtained by TF-MoDISco and Homer

Shared TFs between TF-MoDISco and Homer: #62

TF Name	Modisco	Homer
Elk4	Pattern Name Modisco Significance metacluster_1/pattern_0 0.00107283 metacluster_1/pattern_14 0.0599438	Pattern Name Homer Significance motif2.motif 5.70936e-07
Elk3	Pattern Name Modisco Significance metacluster_1/pattern_0 0.0010647999999999999	Pattern Name Homer Significance motif2.motif 9.03309e-05
Elf5	Pattern Name Modisco Significance metacluster_1/pattern_0 0.025013099999999996 metacluster_1/pattern_14 0.0314718	Pattern Name Homer Significance motif2.motif 0.043332800000000005
Zfp143	Pattern Name Modisco Significance metacluster_1/pattern_10 9.63309e-22	Pattern Name Homer Significance motif5.motif 4.01693e-07
Klf8	Pattern Name Modisco Significance metacluster_1/pattern_1 0.000680465	Pattern Name Homer Significance motif3.motif 0.00072964
Sp5	Pattern Name Modisco Significance metacluster_1/pattern_1 0.020424599999999998	Pattern Name Homer Significance motif18.motif 0.0346749
Fev	Pattern Name Modisco Significance metacluster_1/pattern_0 0.000783408	Pattern Name Homer Significance motif2.motif 0.00324036
Sp2	Pattern Name Modisco Significance metacluster_1/pattern_1 4.35784e-06 metacluster_1/pattern_8 0.000126722 metacluster_1/pattern_12 0.00233514 metacluster_1/pattern_15 0.00285543	Pattern Name Homer Significance motif3.motif 0.00861135
Nfyc	Pattern Name Modisco Significance metacluster_1/pattern_4 3.9074300000000006e-10	Pattern Name Homer Significance motif8.motif 7.4377e-06
Sall4	Pattern Name Modisco Significance metacluster_1/pattern_1 0.0523688	Pattern Name Homer Significance motif18.motif 0.0399691
Ets1	Pattern Name Modisco Significance metacluster_1/pattern_0 0.000991736 metacluster_1/pattern_7 0.0443844 metacluster_1/pattern_14 0.0115288	Pattern Name Homer Significance motif2.motif 1.4743599999999999e-05
Elf4	Pattern Name Modisco Significance metacluster_1/pattern_0 0.00453066	Pattern Name Homer Significance motif2.motif 0.00168351
Pbx3	Pattern Name Modisco Significance metacluster_1/pattern_4 4.79861e-06	Pattern Name Homer Significance motif8.motif 0.000819128
Tcf7	Pattern Name Modisco Significance metacluster_1/pattern_11 0.013709299999999999	Pattern Name Homer Significance motif17.motif 0.050937199999999995
Klf7	Pattern Name Modisco Significance metacluster_1/pattern_1 0.00047851699999999997	Pattern Name Homer Significance motif3.motif 0.00072964
Nfyb	Pattern Name Modisco Significance metacluster_1/pattern_4 7.226269999999999e-14	Pattern Name Homer Significance motif8.motif 5.5477300000000004e-08
Ctcfl	Pattern Name Modisco Significance metacluster_1/pattern_2 6.25238e-08	Pattern Name Homer Significance motif1.motif 0.000879726
Etv6	Pattern Name Modisco Significance metacluster_1/pattern_0 0.000964335 metacluster_1/pattern_14 0.0314718	Pattern Name Homer Significance motif2.motif 0.00256126
Yy1	Pattern Name Modisco Significance metacluster_1/pattern_8 7.065130000000001e-06	Pattern Name Homer Significance motif15.motif 6.2407e-05
Klf1	Pattern Name Modisco Significance metacluster_1/pattern_1 0.031750099999999996	Pattern Name Homer Significance motif3.motif 0.0412843
Taf1	Pattern Name Modisco Significance metacluster_1/pattern_8 3.2952300000000002e-06	Pattern Name Homer Significance motif15.motif 0.00132524
Ctcf	Pattern Name Modisco Significance metacluster_1/pattern_2 5.735370000000001e-15	Pattern Name Homer Significance motif1.motif 0.000448166
Etv2	Pattern Name Modisco Significance metacluster_1/pattern_0 2.45437e-05 metacluster_1/pattern_14 0.0115288	Pattern Name Homer Significance motif2.motif 0.00025646
Elf1	Pattern Name Modisco Significance metacluster_1/pattern_0 0.00262069	Pattern Name Homer Significance motif2.motif 0.013055500000000001
Klf6	Pattern Name Modisco Significance metacluster_1/pattern_1 0.00047851699999999997	Pattern Name Homer Significance motif3.motif 0.00717762
Etv5	Pattern Name Modisco Significance metacluster_1/pattern_0 0.00035459699999999995	Pattern Name Homer Significance motif2.motif 1.5335900000000002e-07
Spic	Pattern Name Modisco Significance metacluster_1/pattern_0 0.05955560000000001	Pattern Name Homer Significance motif2.motif 0.0181753
Tbx2	Pattern Name Modisco Significance metacluster_1/pattern_10 8.78241e-14	Pattern Name Homer Significance motif5.motif 5.2521e-05
Klf4	Pattern Name Modisco Significance metacluster_1/pattern_1 0.00873906	Pattern Name Homer Significance motif3.motif 0.0109953
Erg	Pattern Name Modisco Significance metacluster_1/pattern_0 0.000991736 metacluster_1/pattern_14 0.042299800000000005	Pattern Name Homer Significance motif2.motif 7.60197e-07
Klf5	Pattern Name Modisco Significance metacluster_1/pattern_1 0.011325299999999998	Pattern Name Homer Significance motif3.motif 0.00412531
Nfya	Pattern Name Modisco Significance metacluster_1/pattern_4 1.1546700000000001e-08	Pattern Name Homer Significance motif8.motif 4.02441e-06
Gabpa	Pattern Name Modisco Significance metacluster_1/pattern_0 0.0010647999999999999	Pattern Name Homer Significance motif2.motif 0.00256126
Sp3	Pattern Name Modisco Significance metacluster_1/pattern_1 5.9100300000000006e-06 metacluster_1/pattern_8 0.00482555 metacluster_1/pattern_12 0.043067900000000006 metacluster_1/pattern_15 0.00616209	Pattern Name Homer Significance motif3.motif 0.00717762
Sp4	Pattern Name Modisco Significance metacluster_1/pattern_1 0.00128071 metacluster_1/pattern_8 0.0508835	Pattern Name Homer Significance motif3.motif 0.046269
Foxi1	Pattern Name Modisco Significance metacluster_1/pattern_4 3.1545799999999997e-06	Pattern Name Homer Significance motif8.motif 0.00134469
Nrf1	Pattern Name Modisco Significance metacluster_1/pattern_3 2.23413e-09	Pattern Name Homer Significance motif7.motif 0.00144549
Lef1	Pattern Name Modisco Significance metacluster_1/pattern_11 0.0317892	Pattern Name Homer Significance motif17.motif 0.0166305
E2f1	Pattern Name Modisco Significance metacluster_1/pattern_1 0.00915582	Pattern Name Homer Significance motif3.motif 0.0167046
Tcf7l2	Pattern Name Modisco Significance metacluster_1/pattern_11 3.56943e-05	Pattern Name Homer Significance motif17.motif 0.032283299999999994
Elk1	Pattern Name Modisco Significance metacluster_1/pattern_0 0.00107283	Pattern Name Homer Significance motif2.motif 5.90452e-05
Elf2	Pattern Name Modisco Significance metacluster_1/pattern_0 0.00779534 metacluster_1/pattern_14 0.03932940000000001	Pattern Name Homer Significance motif2.motif 0.0374263
Egr1	Pattern Name Modisco Significance metacluster_1/pattern_1 0.0421782	Pattern Name Homer Significance motif3.motif 0.00665238
Ehf	Pattern Name Modisco Significance metacluster_1/pattern_0 0.00779534	Pattern Name Homer Significance motif2.motif 0.00452826
Tcf3	Pattern Name Modisco Significance metacluster_1/pattern_11 3.96961e-05	Pattern Name Homer Significance motif17.motif 0.0166305
Elf3	Pattern Name Modisco Significance metacluster_1/pattern_0 0.021092700000000002 metacluster_1/pattern_14 0.042299800000000005	Pattern Name Homer Significance motif2.motif 0.0295632
E2f4	Pattern Name Modisco Significance metacluster_1/pattern_1 0.0004556	Pattern Name Homer Significance motif3.motif 0.0100418
Thap11	Pattern Name Modisco Significance metacluster_1/pattern_10 4.44222e-21	Pattern Name Homer Significance motif5.motif 4.32113e-07
Zbtb33	Pattern Name Modisco Significance metacluster_1/pattern_15 7.60047e-06	Pattern Name Homer Significance motif16.motif 0.00156018
Rela	Pattern Name Modisco Significance metacluster_1/pattern_16 0.00122823	Pattern Name Homer Significance motif18.motif 0.0346749
XP_911724.4	Pattern Name Modisco Significance metacluster_1/pattern_0 0.0010647999999999999	Pattern Name Homer Significance motif2.motif 2.08234e-05
Etv3	Pattern Name Modisco Significance metacluster_1/pattern_0 0.0010647999999999999	Pattern Name Homer Significance motif2.motif 1.71918e-05
Klf3	Pattern Name Modisco Significance metacluster_1/pattern_1 1.5641400000000002e-05 metacluster_1/pattern_8 0.057522699999999996	Pattern Name Homer Significance motif3.motif 0.00171358
Fli1	Pattern Name Modisco Significance metacluster_1/pattern_0 0.00101768 metacluster_1/pattern_14 0.042299800000000005	Pattern Name Homer Significance motif2.motif 2.3733299999999998e-06
Zfp281	Pattern Name Modisco Significance metacluster_1/pattern_1 0.0202285	Pattern Name Homer Significance motif18.motif 0.0567534
Etv1	Pattern Name Modisco Significance metacluster_1/pattern_0 0.00121407	Pattern Name Homer Significance motif2.motif 3.89215e-07
Etv4	Pattern Name Modisco Significance metacluster_1/pattern_0 0.0010647999999999999	Pattern Name Homer Significance motif2.motif 0.00178697
Tcf7l1	Pattern Name Modisco Significance metacluster_1/pattern_11 0.000713926	Pattern Name Homer Significance motif17.motif 0.026615100000000003
Egr2	Pattern Name Modisco Significance metacluster_1/pattern_1 0.033979 metacluster_1/pattern_8 0.0508835	Pattern Name Homer Significance motif3.motif 0.0198773
Spdef	Pattern Name Modisco Significance metacluster_1/pattern_0 0.018027	Pattern Name Homer Significance motif2.motif 0.054351699999999996
Sp1	Pattern Name Modisco Significance metacluster_1/pattern_1 0.00035822800000000004 metacluster_1/pattern_8 0.00482555 metacluster_1/pattern_12 0.00799383 metacluster_1/pattern_15 0.03302940000000001	Pattern Name Homer Significance motif3.motif 0.037433499999999995 motif18.motif 0.0346749
Klf12	Pattern Name Modisco Significance metacluster_1/pattern_1 0.0121331	Pattern Name Homer Significance motif3.motif 0.0100418

Unique TF-MoDISco TFs: #80

TF Name	Modisco	Homer
Runx1	Pattern Name Modisco Significance metacluster_1/pattern_6 0.00121217	Absent
Nfkb2	Pattern Name Modisco Significance metacluster_1/pattern_16 7.26064e-05	Absent
Stat4	Pattern Name Modisco Significance metacluster_1/pattern_0 0.050425199999999996	Absent
Tfeb	Pattern Name Modisco Significance metacluster_1/pattern_9 0.000340158	Absent
Batf3	Pattern Name Modisco Significance metacluster_1/pattern_5 0.0107084	Absent
Irf1	Pattern Name Modisco Significance metacluster_1/pattern_5 3.50134e-12	Absent
Mef2d	Pattern Name Modisco Significance metacluster_1/pattern_18 2.5819599999999996e-09	Absent
Bhlhe40	Pattern Name Modisco Significance metacluster_1/pattern_9 0.0074838000000000005	Absent
Irf8	Pattern Name Modisco Significance metacluster_1/pattern_0 0.0240158 metacluster_1/pattern_5 2.55128e-06	Absent
Spi1	Pattern Name Modisco Significance metacluster_1/pattern_0 0.051172 metacluster_1/pattern_14 0.0534962	Absent
Egr3	Pattern Name Modisco Significance metacluster_1/pattern_1 0.0457559	Absent
Nfil3	Pattern Name Modisco Significance metacluster_1/pattern_12 0.0354263	Absent
Irf9	Pattern Name Modisco Significance metacluster_1/pattern_5 0.00274814	Absent
Hlf	Pattern Name Modisco Significance metacluster_1/pattern_9 0.022927200000000002 metacluster_1/pattern_12 0.0276078	Absent
Stat2	Pattern Name Modisco Significance metacluster_1/pattern_5 0.00316481	Absent
Rfx2	Pattern Name Modisco Significance metacluster_1/pattern_13 0.0421297	Absent
Mef2c	Pattern Name Modisco Significance metacluster_1/pattern_18 2.5819599999999996e-09	Absent
Irf7	Pattern Name Modisco Significance metacluster_1/pattern_5 0.000141117	Absent
Irf4	Pattern Name Modisco Significance metacluster_1/pattern_0 0.0255606 metacluster_1/pattern_5 0.0481705	Absent
Tfe3	Pattern Name Modisco Significance metacluster_1/pattern_9 0.00118041	Absent
Relb	Pattern Name Modisco Significance metacluster_1/pattern_16 0.00276198	Absent
Arntl	Pattern Name Modisco Significance metacluster_1/pattern_9 0.00903571	Absent
Rfx4	Pattern Name Modisco Significance metacluster_1/pattern_13 8.01275e-05	Absent
Nfkb1	Pattern Name Modisco Significance metacluster_1/pattern_16 0.00021202	Absent
Stat1	Pattern Name Modisco Significance metacluster_1/pattern_5 0.00012366700000000002	Absent
Tcfl5	Pattern Name Modisco Significance metacluster_1/pattern_9 0.00798086	Absent
Mitf	Pattern Name Modisco Significance metacluster_1/pattern_9 0.0007131430000000001	Absent
Rfx1	Pattern Name Modisco Significance metacluster_1/pattern_8 0.012642 metacluster_1/pattern_12 0.026961400000000003 metacluster_1/pattern_13 3.69651e-10	Absent
Creb3l2	Pattern Name Modisco Significance metacluster_1/pattern_9 0.0209984	Absent
Atf7	Pattern Name Modisco Significance metacluster_1/pattern_9 0.0199777 metacluster_1/pattern_12 0.000554584	Absent
Mxi1	Pattern Name Modisco Significance metacluster_1/pattern_8 0.0508835	Absent
Rel	Pattern Name Modisco Significance metacluster_1/pattern_16 0.00869417	Absent
Atf1	Pattern Name Modisco Significance metacluster_1/pattern_9 0.018794599999999998 metacluster_1/pattern_12 0.0179243	Absent
Zfp740	Pattern Name Modisco Significance metacluster_1/pattern_1 0.0421782	Absent
Tef	Pattern Name Modisco Significance metacluster_1/pattern_12 0.0514626	Absent
Creb1	Pattern Name Modisco Significance metacluster_1/pattern_9 0.028482900000000002 metacluster_1/pattern_12 0.00233514	Absent
Creb5	Pattern Name Modisco Significance metacluster_1/pattern_12 0.00103252	Absent
Crem	Pattern Name Modisco Significance metacluster_1/pattern_12 0.0106932	Absent
Zfx	Pattern Name Modisco Significance metacluster_1/pattern_1 0.026437400000000003 metacluster_1/pattern_8 0.00373064 metacluster_1/pattern_12 0.0114432 metacluster_1/pattern_15 0.0011835	Absent
Irf3	Pattern Name Modisco Significance metacluster_1/pattern_5 0.00183897	Absent
Max	Pattern Name Modisco Significance metacluster_1/pattern_9 0.0135347	Absent
Mef2a	Pattern Name Modisco Significance metacluster_1/pattern_18 5.01379e-05	Absent
Srebf2	Pattern Name Modisco Significance metacluster_1/pattern_9 0.0034162 metacluster_1/pattern_12 0.0362792	Absent
Rfx6	Pattern Name Modisco Significance metacluster_1/pattern_13 0.0008888930000000001	Absent
Myc	Pattern Name Modisco Significance metacluster_1/pattern_9 0.024591	Absent
Cbfb	Pattern Name Modisco Significance metacluster_1/pattern_6 0.00535626	Absent
Atf3	Pattern Name Modisco Significance metacluster_1/pattern_12 0.0106932	Absent
Zbtb1	Pattern Name Modisco Significance metacluster_1/pattern_1 0.0537304	Absent
Prdm1	Pattern Name Modisco Significance metacluster_1/pattern_5 0.000112859	Absent
Runx3	Pattern Name Modisco Significance metacluster_1/pattern_6 0.00365566	Absent
Irf2	Pattern Name Modisco Significance metacluster_1/pattern_5 0.00093268	Absent
Srebf1	Pattern Name Modisco Significance metacluster_1/pattern_9 0.028482900000000002	Absent
Mycn	Pattern Name Modisco Significance metacluster_1/pattern_9 0.011581399999999999	Absent
Zscan10	Pattern Name Modisco Significance metacluster_1/pattern_0 0.050425199999999996	Absent
Ets2	Pattern Name Modisco Significance metacluster_1/pattern_14 0.0506171	Absent
Runx2	Pattern Name Modisco Significance metacluster_1/pattern_6 0.00871647	Absent
Bhlhe41	Pattern Name Modisco Significance metacluster_1/pattern_9 0.0161567	Absent
Nfic	Pattern Name Modisco Significance metacluster_1/pattern_17 0.00512136	Absent
Stat3	Pattern Name Modisco Significance metacluster_1/pattern_0 0.051172	Absent
Jun	Pattern Name Modisco Significance metacluster_1/pattern_12 0.0420618	Absent
Npas2	Pattern Name Modisco Significance metacluster_1/pattern_9 0.00429053	Absent
Nfia	Pattern Name Modisco Significance metacluster_1/pattern_17 1.05522e-05	Absent
Usf2	Pattern Name Modisco Significance metacluster_1/pattern_8 0.051330799999999996 metacluster_1/pattern_9 0.00515726 metacluster_1/pattern_12 1.62125e-05	Absent
Mlx	Pattern Name Modisco Significance metacluster_1/pattern_9 0.00865515	Absent
Zfp42	Pattern Name Modisco Significance metacluster_1/pattern_8 0.012642	Absent
Atf2	Pattern Name Modisco Significance metacluster_1/pattern_9 0.041092699999999996 metacluster_1/pattern_12 0.00183645	Absent
Rfx3	Pattern Name Modisco Significance metacluster_1/pattern_13 0.00105156	Absent
Tfec	Pattern Name Modisco Significance metacluster_1/pattern_9 0.00118041	Absent
Fosl2	Pattern Name Modisco Significance metacluster_1/pattern_12 0.013346100000000001	Absent
Clock	Pattern Name Modisco Significance metacluster_1/pattern_9 0.0276853	Absent
Arnt	Pattern Name Modisco Significance metacluster_1/pattern_9 0.0471462	Absent
Jdp2	Pattern Name Modisco Significance metacluster_1/pattern_9 0.0363905 metacluster_1/pattern_12 0.00103252	Absent
Mlxip	Pattern Name Modisco Significance metacluster_1/pattern_9 0.058016	Absent
Nfib	Pattern Name Modisco Significance metacluster_1/pattern_17 1.6690400000000003e-06	Absent
Xbp1	Pattern Name Modisco Significance metacluster_1/pattern_9 0.0483735	Absent
Spib	Pattern Name Modisco Significance metacluster_1/pattern_0 0.00493136 metacluster_1/pattern_5 0.00274814	Absent
Rfx7	Pattern Name Modisco Significance metacluster_1/pattern_13 0.00060019	Absent
Usf1	Pattern Name Modisco Significance metacluster_1/pattern_9 0.00933855 metacluster_1/pattern_12 0.00583914	Absent
Dbp	Pattern Name Modisco Significance metacluster_1/pattern_9 0.040766000000000004	Absent
Zbtb17	Pattern Name Modisco Significance metacluster_1/pattern_1 0.00460312	Absent

Unique Homer TFs: #2

TF Name	Modisco	Homer
Wt1	Absent	Pattern Name Homer Significance motif18.motif 0.0346749
E2f6	Absent	Pattern Name Homer Significance motif3.motif 0.0431205