<!-- ============================================
     ::DATATOOL:: Generated from "pcassay.asn"
     ::DATATOOL:: by application DATATOOL version 2.3.1
     ::DATATOOL:: on 01/17/2012 23:05:10
     ============================================ -->

<!-- ============================================ -->
<!-- This section is mapped from module "NCBI-PCAssay"
================================================= -->

<!--
 $Id: pcassay.asn 282508 2011-05-11 22:47:31Z ywang $
 ===========================================================================

                            PUBLIC DOMAIN NOTICE
               National Center for Biotechnology Information

  This software/database is a "United States Government Work" under the
  terms of the United States Copyright Act.  It was written as part of
  the author's official duties as a United States Government employee and
  thus cannot be copyrighted.  This software/database is freely available
  to the public for use. The National Library of Medicine and the U.S.
  Government have not placed any restriction on its use or reproduction.

  Although all reasonable efforts have been taken to ensure the accuracy
  and reliability of the software and data, the NLM and the U.S.
  Government do not and cannot warrant the performance or results that
  may be obtained by using this software or data. The NLM and the U.S.
  Government disclaim all warranties, express or implied, including
  warranties of performance, merchantability or fitness for any particular
  purpose.

  Please cite the author in any work or product based on this material.

 ===========================================================================

 Authors:  NCBI Structure Group

 File Description:
      ASN.1 definitions for PubChem biological assay data database

 ===========================================================================
-->

<!-- Elements referenced from other modules:
          Pub FROM NCBI-Pub,
          BioSource FROM NCBI-BioSource,
          Date,
          Object-id FROM NCBI-General,
          PC-ID,
          PC-Source,
          PC-XRefData FROM NCBI-PCSubstance -->
<!-- ============================================ -->

<!--
 EXPORTS ;
 Container for multiple Assay Data Submissions
-->
<!ELEMENT PC-AssayContainer (PC-AssaySubmit*)>

<!-- Container for Data Depositions and Assay Definitions -->
<!ELEMENT PC-AssaySubmit (
        PC-AssaySubmit_assay, 
        PC-AssaySubmit_data?, 
        PC-AssaySubmit_revoke?)>
<!-- Assay Description or pre-existing Identifier -->
<!ELEMENT PC-AssaySubmit_assay (
        PC-AssaySubmit_assay_aid | 
        PC-AssaySubmit_assay_aid-source | 
        PC-AssaySubmit_assay_descr | 
        PC-AssaySubmit_assay_aidver)>

<!--   Assay Identifier -->
<!ELEMENT PC-AssaySubmit_assay_aid (%INTEGER;)>

<!--   External Assay Identifier -->
<!ELEMENT PC-AssaySubmit_assay_aid-source (PC-Source)>

<!--   Assay Description (new or updated) -->
<!ELEMENT PC-AssaySubmit_assay_descr (PC-AssayDescription)>

<!--   Assay Identifier/Version (for internal use) -->
<!ELEMENT PC-AssaySubmit_assay_aidver (PC-ID)>

<!-- Assay Data Deposition (vector) -->
<!ELEMENT PC-AssaySubmit_data (PC-AssayResults*)>

<!-- List of SID's whose data is to be suppressed -->
<!ELEMENT PC-AssaySubmit_revoke (PC-AssaySubmit_revoke_E*)>


<!ELEMENT PC-AssaySubmit_revoke_E (%INTEGER;)>

<!--
 Container for multiple Assay Result Sets
 PC-AssayResultsSet ::= SEQUENCE OF PC-AssayResults
 Assay Results provided for a given Substance tested, with respect to the results types defined in the 
   referenced Assay Description
-->
<!ELEMENT PC-AssayResults (
        PC-AssayResults_sid, 
        PC-AssayResults_sid-source?, 
        PC-AssayResults_version?, 
        PC-AssayResults_comment?, 
        PC-AssayResults_outcome?, 
        PC-AssayResults_rank?, 
        PC-AssayResults_data?, 
        PC-AssayResults_url?, 
        PC-AssayResults_xref?, 
        PC-AssayResults_date?)>

<!--
 Internal/External Tracking Information
 Tested Substance ID/Version  [Either valid ID or, 
   if "sid-source" is used, this is a "0" value]
   Note: A valid ID is greater than "0"
-->
<!ELEMENT PC-AssayResults_sid (%INTEGER;)>

<!--
 External Identifier for this Substance
   Note: May be used in-lieu of "sid"
   Note: This is non-optional if "sid" is "0"
-->
<!ELEMENT PC-AssayResults_sid-source (PC-Source)>

<!--
 Version identifier for this AID-SID Result
   Note: Incoming data should set this to be "0"
-->
<!ELEMENT PC-AssayResults_version (%INTEGER;)>

<!--
 Data Annotation/Qualifier and URL to further Depositor Information
 Annotation or qualifier for this Result
-->
<!ELEMENT PC-AssayResults_comment (#PCDATA)>
<!--
 Assay Result Data for this Sample
   Note: Users need populate only those "tid"s, for which there is data, in any order.
 Assay Outcome
-->
<!ELEMENT PC-AssayResults_outcome (%INTEGER;)>

<!--
    inactive	-    Substance is considered Inactive
    active	-    Substance is considered Active
    inconclusive	-    Substance is Inconclusive
    unspecified	-    Substance Outcome is Unspecified
    probe	-    Substance Outcome is Unspecified
-->
<!ATTLIST PC-AssayResults_outcome value (
        inactive |
        active |
        inconclusive |
        unspecified |
        probe
        ) #IMPLIED >


<!--
 Rank of Assay Outcome (for result ordering)
   Note: Larger numbers are more active
-->
<!ELEMENT PC-AssayResults_rank (%INTEGER;)>

<!-- Assay Data Reported for this SID (vector) -->
<!ELEMENT PC-AssayResults_data (PC-AssayData*)>

<!-- Depositor provided URL for this Result -->
<!ELEMENT PC-AssayResults_url (#PCDATA)>

<!--
 annotated Cross-Reference Information
 to be removed, 
 instead regulard TID will be generated
 which are then annotated by xref type
-->
<!ELEMENT PC-AssayResults_xref (PC-AnnotatedXRef*)>

<!-- Pubchem Release Date -->
<!ELEMENT PC-AssayResults_date (Date)>

<!-- Assay Readouts/Results for a Tested Substance -->
<!ELEMENT PC-AssayData (
        PC-AssayData_tid, 
        PC-AssayData_value)>

<!--
 Assay Result Field Type ID (TID)
   Note: Result Field ID's must be greater than "0"
-->
<!ELEMENT PC-AssayData_tid (%INTEGER;)>
<!-- Assay Result, must be the same type as defined for TID -->
<!ELEMENT PC-AssayData_value (
        PC-AssayData_value_ival | 
        PC-AssayData_value_fval | 
        PC-AssayData_value_bval | 
        PC-AssayData_value_sval)>

<!ELEMENT PC-AssayData_value_ival (%INTEGER;)>

<!ELEMENT PC-AssayData_value_fval (%REAL;)>

<!ELEMENT PC-AssayData_value_bval EMPTY>
<!ATTLIST PC-AssayData_value_bval value ( true | false ) #REQUIRED >


<!ELEMENT PC-AssayData_value_sval (#PCDATA)>

<!--
 Assay Description provided by an Organization that describes the assay/protocol performed and defines the 
   measured end-points and parameters to be stored.  An Assay Description is not a database table.  You can 
   define as many Result Definitions as needed and they need not be used by all Substances tested.
 Assay Descriptions can be modified on both description text and Result Definitions after initial submission
 as desired, and such udpates will be tracked in PubChem
-->
<!ELEMENT PC-AssayDescription (
        PC-AssayDescription_aid, 
        PC-AssayDescription_aid-source?, 
        PC-AssayDescription_name, 
        PC-AssayDescription_description?, 
        PC-AssayDescription_protocol?, 
        PC-AssayDescription_comment?, 
        PC-AssayDescription_xref?, 
        PC-AssayDescription_results?, 
        PC-AssayDescription_pub?, 
        PC-AssayDescription_revision?, 
        PC-AssayDescription_target?, 
        PC-AssayDescription_activity-outcome-method?, 
        PC-AssayDescription_dr?, 
        PC-AssayDescription_substance-type?, 
        PC-AssayDescription_grant-number?, 
        PC-AssayDescription_project-category?, 
        PC-AssayDescription_is-panel?, 
        PC-AssayDescription_assay-group?, 
        PC-AssayDescription_panel-info?, 
        PC-AssayDescription_is-mlp-late-stage?, 
        PC-AssayDescription_categorized-comment?)>

<!--
 Internal/External Tracking Information
 Assay Description ID/Version  [Either valid ID
   or, if "aid-source" is used, a "0" dummy value]
   Note: Version is for internal use (only?)
   Note: A valid ID is greater than "0"
-->
<!ELEMENT PC-AssayDescription_aid (PC-ID)>

<!--
 External Identifier for this Assay Description
   Note: May be used in-lieu of "aid"
   Note: This is non-optional if "aid" ID is "0"
-->
<!ELEMENT PC-AssayDescription_aid-source (PC-Source)>

<!--
 Assay Description Information
 Short Assay Name (for display purposes)
-->
<!ELEMENT PC-AssayDescription_name (#PCDATA)>

<!-- Description of Assay -->
<!ELEMENT PC-AssayDescription_description (PC-AssayDescription_description_E*)>


<!ELEMENT PC-AssayDescription_description_E (#PCDATA)>

<!-- Procedure used to generate results -->
<!ELEMENT PC-AssayDescription_protocol (PC-AssayDescription_protocol_E*)>


<!ELEMENT PC-AssayDescription_protocol_E (#PCDATA)>

<!-- Comments or additional information -->
<!ELEMENT PC-AssayDescription_comment (PC-AssayDescription_comment_E*)>


<!ELEMENT PC-AssayDescription_comment_E (#PCDATA)>

<!-- Annotated Cross-Reference Information -->
<!ELEMENT PC-AssayDescription_xref (PC-AnnotatedXRef*)>

<!--
 Allowed Assay Result Types
 Result Definitions (vector)
-->
<!ELEMENT PC-AssayDescription_results (PC-ResultType*)>

<!--
 Additional Information
 Depositor provided publications for this assay
-->
<!ELEMENT PC-AssayDescription_pub (Pub*)>

<!-- Revision identifier for textual description -->
<!ELEMENT PC-AssayDescription_revision (%INTEGER;)>

<!-- Target information -->
<!ELEMENT PC-AssayDescription_target (PC-AssayTargetInfo*)>
<!-- Assay Outcome Qualifier -->
<!ELEMENT PC-AssayDescription_activity-outcome-method (%INTEGER;)>

<!--
    other	-    All Other Type
    screening	-    Primary Screen Assay
    confirmatory	-    Confirmatory Assay
    summary	-    Probe Summary Assay
-->
<!ATTLIST PC-AssayDescription_activity-outcome-method value (
        other |
        screening |
        confirmatory |
        summary
        ) #IMPLIED >


<!-- Dose-Response Attribution -->
<!ELEMENT PC-AssayDescription_dr (PC-AssayDRAttr*)>

<!-- to distinguish the type of substance used in the screening -->
<!ELEMENT PC-AssayDescription_substance-type (%INTEGER;)>
<!ATTLIST PC-AssayDescription_substance-type value (
        small-molecule |
        nucleotide |
        other
        ) #IMPLIED >


<!--
 Grant and project category information
 grant proposal number
 required for 'MLSCN' & 'MLPCN' projects
-->
<!ELEMENT PC-AssayDescription_grant-number (PC-AssayDescription_grant-number_E*)>


<!ELEMENT PC-AssayDescription_grant-number_E (#PCDATA)>

<!--
 to distinguish projects funded through MLSCN, MLPCN or other
 mlscn: assay depositions from MLSCN screen center
 mlpcn: assay depositions from MLPCN screen center
 mlscn-ap: assay depositions from MLSCN assay provider
 mlpcn-ap: assay depositions from MLPCN assay provider
 required for 'MLSCN' & 'MLPCN' projects
 journal-article: to be deprecated; replaced by option 7,8 & 9 to better characterize data from literature 
 literature-extracted: data from literature, extracted by curators
 literature-author: data from literature, submitted by author of articles
 literature-publisher: data from literature, submitted by journals/publishers
 rnaigi: RNAi screenings from RNAi Global Initiative 
-->
<!ELEMENT PC-AssayDescription_project-category (%INTEGER;)>

<!--
    journal-article	-  to be deprecated
-->
<!ATTLIST PC-AssayDescription_project-category value (
        mlscn |
        mlpcn |
        mlscn-ap |
        mlpcn-ap |
        journal-article |
        assay-vendor |
        literature-extracted |
        literature-author |
        literature-publisher |
        rnaigi |
        other
        ) #IMPLIED >


<!--
 annotation to indicate whether an assay is a panel, e.g. containing multiple components, or belongs to a group    
 annotation for panel assay, e.g. to indicate that this assay
 contains multiple members/components. 
 A panel assay can be one assay reporting readouts for
 many targets, or reporting readouts for different
 cell lines, or different organisms
 examples such as bioassay containing kinase profiling data
 or bioassay containing cytoxicity data for multiple cell lines
 or bioassay containing screening data from different stages, 
 such as primary screening, follow ups
-->
<!ELEMENT PC-AssayDescription_is-panel EMPTY>
<!ATTLIST PC-AssayDescription_is-panel value ( true | false ) #REQUIRED >


<!--
 annotation for assay gruop information, e.g. this 
 assay belongs to a group of assay associated by 
 a unique name, e.g. the value assigned to 'assay-group',  
 assays belonging to this group can be 
 retrieved using this unique name
 it is depositor's responsibility to make the name 
 distinct if necessary
 this can be used as the mechanism to specify 'related bioassays'
 before hand so it is not necessary to update the descriptions of
 related assays when new group member submitted to PubChem 
-->
<!ELEMENT PC-AssayDescription_assay-group (PC-AssayDescription_assay-group_E*)>


<!ELEMENT PC-AssayDescription_assay-group_E (#PCDATA)>

<!--
 for 'panel' type of bioassay only
 store assay panel member information
-->
<!ELEMENT PC-AssayDescription_panel-info (PC-AssayPanel)>

<!-- verification for 'late-stage-data' deposition -->
<!ELEMENT PC-AssayDescription_is-mlp-late-stage EMPTY>
<!ATTLIST PC-AssayDescription_is-mlp-late-stage value ( true | false ) #REQUIRED >


<!-- to report categorized description/comment by associating with a category title  -->
<!ELEMENT PC-AssayDescription_categorized-comment (PC-CategorizedComment*)>

<!--
 Description for Panel Assay
 Describe general information about the panel, and link to information for each panel member 
-->
<!ELEMENT PC-AssayPanel (
        PC-AssayPanel_name, 
        PC-AssayPanel_descr?, 
        PC-AssayPanel_member?)>

<!-- short name for the panel, such as 'Kinase Profiling' -->
<!ELEMENT PC-AssayPanel_name (#PCDATA)>

<!-- short description of this panel -->
<!ELEMENT PC-AssayPanel_descr (#PCDATA)>

<!-- store panel member information -->
<!ELEMENT PC-AssayPanel_member (PC-AssayPanelMember*)>

<!-- Specific information about each panel member(or component), such as target, cell line name, cross-reference ...  -->
<!ELEMENT PC-AssayPanelMember (
        PC-AssayPanelMember_mid, 
        PC-AssayPanelMember_name?, 
        PC-AssayPanelMember_description?, 
        PC-AssayPanelMember_protocol?, 
        PC-AssayPanelMember_comment?, 
        PC-AssayPanelMember_target?, 
        PC-AssayPanelMember_xref?, 
        PC-AssayPanelMember_activity-outcome-method?, 
        PC-AssayPanelMember_dr?, 
        PC-AssayPanelMember_categorized-comment?)>

<!--
 ID for panel member 
 if a kinase panel with 300 kinases, ID will range from 1 to 300  
 TIDs of the same panel member to be grouped based on panel member ID
-->
<!ELEMENT PC-AssayPanelMember_mid (%INTEGER;)>

<!-- short name for this panel member  -->
<!ELEMENT PC-AssayPanelMember_name (#PCDATA)>

<!--
 description about specifics of this panel member
 such as about cell line, or target information 
-->
<!ELEMENT PC-AssayPanelMember_description (#PCDATA)>

<!-- Specific procedure used to generate results for the panel member -->
<!ELEMENT PC-AssayPanelMember_protocol (PC-AssayPanelMember_protocol_E*)>


<!ELEMENT PC-AssayPanelMember_protocol_E (#PCDATA)>

<!-- Comments or additional information -->
<!ELEMENT PC-AssayPanelMember_comment (PC-AssayPanelMember_comment_E*)>


<!ELEMENT PC-AssayPanelMember_comment_E (#PCDATA)>

<!-- often provided for profiling assays across protein families -->
<!ELEMENT PC-AssayPanelMember_target (PC-AssayTargetInfo*)>

<!-- annotated Cross-Reference Information -->
<!ELEMENT PC-AssayPanelMember_xref (PC-AnnotatedXRef*)>
<!-- Assay Outcome Qualifier -->
<!ELEMENT PC-AssayPanelMember_activity-outcome-method (%INTEGER;)>

<!--
    other	-    All Other Type
    screening	-    Primary Screen Assay
    confirmatory	-    Confirmatory Assay
    summary	-    Probe Summary Assay
-->
<!ATTLIST PC-AssayPanelMember_activity-outcome-method value (
        other |
        screening |
        confirmatory |
        summary
        ) #IMPLIED >


<!-- Dose-Response Attribution within the panel member -->
<!ELEMENT PC-AssayPanelMember_dr (PC-AssayDRAttr*)>

<!-- to report categorized description/comment by associating with a category title  -->
<!ELEMENT PC-AssayPanelMember_categorized-comment (PC-CategorizedComment*)>

<!--
 Definition for Categorized description/comment 
 This field is added to provide flexibility for depositors to present textual description/comments in a desirable way 
 and to facilitate information validation by the depositor and data exchange with PubChem 
-->
<!ELEMENT PC-CategorizedComment (
        PC-CategorizedComment_title, 
        PC-CategorizedComment_comment)>

<!-- title for the description/comment -->
<!ELEMENT PC-CategorizedComment_title (#PCDATA)>

<!-- description/comment content -->
<!ELEMENT PC-CategorizedComment_comment (PC-CategorizedComment_comment_E*)>


<!ELEMENT PC-CategorizedComment_comment_E (#PCDATA)>

<!--
  Assay Dose-response attribute information used to define a set of readouts
    as being part of a dose-response curve (for curve plotting/analysis)
-->
<!ELEMENT PC-AssayDRAttr (
        PC-AssayDRAttr_id, 
        PC-AssayDRAttr_descr?, 
        PC-AssayDRAttr_dn?, 
        PC-AssayDRAttr_rn?, 
        PC-AssayDRAttr_type?)>

<!--
 Unique dose-response test set identifier
   Note: A valid ID is greater than "0"
-->
<!ELEMENT PC-AssayDRAttr_id (%INTEGER;)>

<!-- Dose-Response Curve Description (used as curve title) -->
<!ELEMENT PC-AssayDRAttr_descr (#PCDATA)>

<!-- Dose Axis Description (used as axis name) -->
<!ELEMENT PC-AssayDRAttr_dn (#PCDATA)>

<!-- Response Axis Description (used as axis name) -->
<!ELEMENT PC-AssayDRAttr_rn (#PCDATA)>

<!ELEMENT PC-AssayDRAttr_type (%INTEGER;)>

<!--
    experimental	-  dose-response data points measured directly by experiment
    calculated	-  dose-response data points derived from fitted curve
-->
<!ATTLIST PC-AssayDRAttr_type value (
        experimental |
        calculated
        ) #IMPLIED >


<!--
 Molecular target information provides by organization describes the functionality of the target, 
 facilitates the linking between PubChem bioassays, and the linking between target molecule to other NCBI resources
-->
<!ELEMENT PC-AssayTargetInfo (
        PC-AssayTargetInfo_name, 
        PC-AssayTargetInfo_mol-id, 
        PC-AssayTargetInfo_molecule-type?, 
        PC-AssayTargetInfo_organism?, 
        PC-AssayTargetInfo_descr?, 
        PC-AssayTargetInfo_comment?)>

<!-- Molecular name of target -->
<!ELEMENT PC-AssayTargetInfo_name (#PCDATA)>

<!-- NCBI database identifier of the target molecule -->
<!ELEMENT PC-AssayTargetInfo_mol-id (%INTEGER;)>
<!-- Assay Target Type -->
<!ELEMENT PC-AssayTargetInfo_molecule-type (%INTEGER;)>

<!--
    protein	-  mol-id: NCBI Protein GI 
    dna	-  mol-id: NCBI Nucleotide GI
    rna	-  mol-id: NCBI Nucleotide GI
    gene	-  mol-id: NCBI Gene ID
    biosystem	-  mol-id: NCBI BioSystems ID
-->
<!ATTLIST PC-AssayTargetInfo_molecule-type value (
        protein |
        dna |
        rna |
        gene |
        biosystem |
        other
        ) #IMPLIED >


<!-- Target Organism -->
<!ELEMENT PC-AssayTargetInfo_organism (BioSource)>

<!-- Target Description  (e.g., cellular functionality and location) -->
<!ELEMENT PC-AssayTargetInfo_descr (#PCDATA)>

<!-- Comments or Additional Information -->
<!ELEMENT PC-AssayTargetInfo_comment (PC-AssayTargetInfo_comment_E*)>


<!ELEMENT PC-AssayTargetInfo_comment_E (#PCDATA)>

<!-- Annotated Cross-Reference (XRef) Information to allow the XRef to be qualified, as to its meaning or context -->
<!ELEMENT PC-AnnotatedXRef (
        PC-AnnotatedXRef_xref, 
        PC-AnnotatedXRef_comment?, 
        PC-AnnotatedXRef_type?)>

<!-- Cross-Reference Information -->
<!ELEMENT PC-AnnotatedXRef_xref (PC-XRefData)>

<!-- Annotation qualifier describing Cross-Reference meaning -->
<!ELEMENT PC-AnnotatedXRef_comment (#PCDATA)>

<!ELEMENT PC-AnnotatedXRef_type (%INTEGER;)>

<!--
    pcit	-  primary PMID/citation directly associated with the current assay data 
    pgene	-  gene encoding the protein assay target
-->
<!ATTLIST PC-AnnotatedXRef_type value (
        pcit |
        pgene
        ) #IMPLIED >


<!-- Definition of Allowed Result Types for a given Assay -->
<!ELEMENT PC-ResultType (
        PC-ResultType_tid, 
        PC-ResultType_name, 
        PC-ResultType_description?, 
        PC-ResultType_type, 
        PC-ResultType_constraints?, 
        PC-ResultType_unit?, 
        PC-ResultType_sunit?, 
        PC-ResultType_transform?, 
        PC-ResultType_stransform?, 
        PC-ResultType_tc?, 
        PC-ResultType_ac?, 
        PC-ResultType_panel-info?, 
        PC-ResultType_annot?)>

<!--
 Tracking or Description Information
 Assay Result Field Type ID (TID)
-->
<!ELEMENT PC-ResultType_tid (%INTEGER;)>

<!-- Result Field Name (short name for display) -->
<!ELEMENT PC-ResultType_name (#PCDATA)>

<!-- Result Field Description -->
<!ELEMENT PC-ResultType_description (PC-ResultType_description_E*)>


<!ELEMENT PC-ResultType_description_E (#PCDATA)>
<!--
 Result Data Type and Validation Information
 Result Data Type
-->
<!ELEMENT PC-ResultType_type (%INTEGER;)>
<!ATTLIST PC-ResultType_type value (
        float |
        int |
        bool |
        string
        ) #IMPLIED >

<!--
 Allowed Values, used for validating incoming data
 If type is "float"
-->
<!ELEMENT PC-ResultType_constraints (
        PC-ResultType_constraints_fset | 
        PC-ResultType_constraints_fmin | 
        PC-ResultType_constraints_fmax | 
        PC-ResultType_constraints_frange | 
        PC-ResultType_constraints_iset | 
        PC-ResultType_constraints_imin | 
        PC-ResultType_constraints_imax | 
        PC-ResultType_constraints_irange | 
        PC-ResultType_constraints_sset)>

<!--   Allowed values must be equal to one of these -->
<!ELEMENT PC-ResultType_constraints_fset (PC-ResultType_constraints_fset_E*)>


<!ELEMENT PC-ResultType_constraints_fset_E (%REAL;)>

<!--   Allowed values (x) must be [ fmin <= x ] -->
<!ELEMENT PC-ResultType_constraints_fmin (%REAL;)>

<!--   Allowed values (x) must be [ x <= fmax ] -->
<!ELEMENT PC-ResultType_constraints_fmax (%REAL;)>

<!--   Minimum/Maximum Range [ min <= x <= max ] -->
<!ELEMENT PC-ResultType_constraints_frange (PC-RealMinMax)>

<!--
 If type is "int"
   Allowed values must be equal to one of these
-->
<!ELEMENT PC-ResultType_constraints_iset (PC-ResultType_constraints_iset_E*)>


<!ELEMENT PC-ResultType_constraints_iset_E (%INTEGER;)>

<!--   Allowed values (x) must be [ imin <= x ] -->
<!ELEMENT PC-ResultType_constraints_imin (%INTEGER;)>

<!--   Allowed values (x) must be [ x <= imax ] -->
<!ELEMENT PC-ResultType_constraints_imax (%INTEGER;)>

<!--   Minimum/Maximum Range [ min <= x <= max ] -->
<!ELEMENT PC-ResultType_constraints_irange (PC-IntegerMinMax)>

<!--
 If type is "string"
   Allowed values must be equal to one of these
-->
<!ELEMENT PC-ResultType_constraints_sset (PC-ResultType_constraints_sset_E*)>


<!ELEMENT PC-ResultType_constraints_sset_E (#PCDATA)>
<!--
 Unit information provides the units for the values reported for this TID.  For example, if the values 
   reported for this TID are a concentration, e.g., micro-molar, setting the unit "um" allows PubChem to 
   know that the value, e.g., "1.3", is actually "1.3 uM".  This also allows PubChem to properly report the 
   units when displaying the reported values for this TID.  If the enumerated units provided below are 
   insufficient, you may represent the units as a string in the optional "sunit" field (see below).
 Units for Value
-->
<!ELEMENT PC-ResultType_unit (%INTEGER;)>

<!--
    ppt	-  Parts per Thousand
    ppm	-  Parts per Million
    ppb	-  Parts per Billion
    mm	-  milliM
    um	-  microM
    nm	-  nanoM
    pm	-  picoM
    fm	-  femtoM
    mgml	-  milligrams per mL
    ugml	-  micrograms per mL
    ngml	-  nanograms per mL
    pgml	-  picograms per mL
    fgml	-  femtograms per mL
    m	-  Molar
    percent	-  Percent
    ratio	-  Ratio
    sec	-  Seconds
    rsec	-  Reciprocal Seconds
    min	-  Minutes
    rmin	-  Reciprocal Minutes
    day	-  Days
    rday	-  Reciprocal Days
    ml-min-kg	-  milliliter / minute / kilogram
    l-kg	-  liter / kilogram
    hr-ng-ml	-  hour * nanogram / milliliter
    cm-sec	-  centimeter / second
    mg-kg	-  milligram / kilogram
-->
<!ATTLIST PC-ResultType_unit value (
        ppt |
        ppm |
        ppb |
        mm |
        um |
        nm |
        pm |
        fm |
        mgml |
        ugml |
        ngml |
        pgml |
        fgml |
        m |
        percent |
        ratio |
        sec |
        rsec |
        min |
        rmin |
        day |
        rday |
        ml-min-kg |
        l-kg |
        hr-ng-ml |
        cm-sec |
        mg-kg |
        none |
        unspecified
        ) #IMPLIED >


<!--
 ATTENTION: sunit field is DEPRECATED. It is no longer
            supported and remains for legacy data only.
 Unit Type (as a String)
-->
<!ELEMENT PC-ResultType_sunit (#PCDATA)>
<!--
 Value Transform information qualifies the values reported for this TID.  For example, if the values
   reported for this TID are "-Log10 GI50", you may want to consider setting
   the "nlog" value below.  In doing so, PubChem would know that the value, e.g., "5.0" 
   is actually "1.0e-5".  If the transformation applied is not listed, you may represent
   this transformation as a string in the "stransform" (see below) for eventual inclusion 
   in the enumerated transform list below.


 ATTENTION: transform field is DEPRECATED. It is no longer
            supported and remains for legacy data only.
 Value Type Details
-->
<!ELEMENT PC-ResultType_transform (%INTEGER;)>

<!--
    linear	-  Linear Scale (x)
    ln	-  Natural Log Scale (ln x)
    log	-  Log Base 10 Scale (log10 x)
    reciprocal	-  Reciprocal Scale (1/x)
    negative	-  Negative Linear Scale (-x)
    nlog	-  Negative Log Base 10 Scale (-log10 x)
    nln	-  Negative Natural Log Scane (-ln x)
-->
<!ATTLIST PC-ResultType_transform value (
        linear |
        ln |
        log |
        reciprocal |
        negative |
        nlog |
        nln
        ) #IMPLIED >


<!--
 ATTENTION: stransform field is DEPRECATED. It is no longer
            supported and remains for legacy data only.
 Value Transform Type (as a String)
-->
<!ELEMENT PC-ResultType_stransform (#PCDATA)>

<!-- Tested concentration attribute -->
<!ELEMENT PC-ResultType_tc (PC-ConcentrationAttr)>

<!--
 if true, indicates that this TID field 
 provides active concentration summary by 
 reporting the concentration which produces 
 50% of the maximum possible biological response
 such as IC50, EC50, AC50, GI50 etc. 
 or by reporting constant parameters such as Ki, 
 that based on which the activity outcome in this assay is called   
-->
<!ELEMENT PC-ResultType_ac EMPTY>
<!ATTLIST PC-ResultType_ac value ( true | false ) #REQUIRED >


<!--
 needed for panel assay only
 each panel member may have a number of TID columns reported
 such TIDs are grouped by panel member ID, see PC-AssayPanelMemberInfo
-->
<!ELEMENT PC-ResultType_panel-info (PC-AssayPanelTestResult)>

<!--
 treat substance associated cross-reference as regular TID
 web servers would make a link 
 to the corresponding record in Entrez databases
 treat substance associated target information as regular TID
 for example, for RNAi screening data, each 'substance' may
 correspond to a specific gene target
-->
<!ELEMENT PC-ResultType_annot (%INTEGER;)>

<!--
    pmid	-  PubMed ID
    mmdb	-  MMDB ID
    url	-  indicate  TID data is a url that provides supplementary information
    protein-gi	-  GenBank General ID (GI) for a Protein
    nucleotide-gi	-  GenBank General ID (GI) for a Nucleotide 
    taxonomy	-  Taxonomy ID for an Organism
    mim	-  MIM, Mendelian Inheritance in Man, ID 
    gene	-  Entrez Gene ID
    probe	-  Entrez Probe ID
    aid	-  PubChem BioAssay ID, may be used in 'Summary' assay
    sid	-  PubChem Substance ID, may be used in 'Summary' assay 
    cid	-  PubChem Compound ID 
    protein-target-gi	-  GenBank General ID (GI) for a Protein target
    biosystems-target-id	-  NCBI BioSystems ID 
    target-name	-  target name
    target-descr	-  brief target description 
    target-tax-id	-  NCBI Taxonomy ID for target molecule 
    gene-target-id	-  NCBI Gene ID for a gene target 
    dna-nucleotide-target-gi	-  GenBank General ID (GI) for a DNA Nucleotide target 
    rna-nucleotide-target-gi	-  GenBank General ID (GI) for a RNA Nucleotide target 
-->
<!ATTLIST PC-ResultType_annot value (
        pmid |
        mmdb |
        url |
        protein-gi |
        nucleotide-gi |
        taxonomy |
        mim |
        gene |
        probe |
        aid |
        sid |
        cid |
        protein-target-gi |
        biosystems-target-id |
        target-name |
        target-descr |
        target-tax-id |
        gene-target-id |
        dna-nucleotide-target-gi |
        rna-nucleotide-target-gi
        ) #IMPLIED >


<!ELEMENT PC-AssayPanelTestResult (
        PC-AssayPanelTestResult_mid, 
        PC-AssayPanelTestResult_readout-annot?)>

<!--
 panel member ID, see PC-AssayPanelMemberInfo
 track association between a group of TIDs and panel member
-->
<!ELEMENT PC-AssayPanelTestResult_mid (%INTEGER;)>

<!ELEMENT PC-AssayPanelTestResult_readout-annot (%INTEGER;)>

<!--
    regular	-  to indicate this TID column is a regular readout
    outcome	-  to indicate this TID column is  "outcome" of the particular panel member
    score	-  to indicate this TID column reports activity score of the particular panel member
         to be used for neighboring assays
    ac	-  to indicate this TID column is "active concentration"   
         'outcome' and 'ac' type of TID are to be used for data analysis 
         across members of panel
         or across multiple assays including other panel assays
-->
<!ATTLIST PC-AssayPanelTestResult_readout-annot value (
        regular |
        outcome |
        score |
        ac
        ) #IMPLIED >


<!--The concentration attribute is to indicate that the readout under this test result field is biological concentration-response data, the attribute provides the value and unit of the tested concentration -->
<!ELEMENT PC-ConcentrationAttr (
        PC-ConcentrationAttr_concentration, 
        PC-ConcentrationAttr_unit, 
        PC-ConcentrationAttr_dr-id?)>

<!ELEMENT PC-ConcentrationAttr_concentration (%REAL;)>
<!-- Units for Concentration -->
<!ELEMENT PC-ConcentrationAttr_unit (%INTEGER;)>

<!--
    um	-  microM
-->
<!ATTLIST PC-ConcentrationAttr_unit value (
        um
        ) #IMPLIED >


<!-- Dose-Response Attribution ID (if applicable) -->
<!ELEMENT PC-ConcentrationAttr_dr-id (%INTEGER;)>

<!-- Mininum and Maximum Constraints on an Integer Value (used for validating incoming data) -->
<!ELEMENT PC-IntegerMinMax (
        PC-IntegerMinMax_min, 
        PC-IntegerMinMax_max)>

<!-- Minimum Value Allowed -->
<!ELEMENT PC-IntegerMinMax_min (%INTEGER;)>

<!-- Maximum Value Allowed -->
<!ELEMENT PC-IntegerMinMax_max (%INTEGER;)>

<!-- Mininum and Maximum Constraints on a Real Value (used for validating incoming data) -->
<!ELEMENT PC-RealMinMax (
        PC-RealMinMax_min, 
        PC-RealMinMax_max)>

<!-- Minimum Value Allowed -->
<!ELEMENT PC-RealMinMax_min (%REAL;)>

<!-- Maximum Value Allowed -->
<!ELEMENT PC-RealMinMax_max (%REAL;)>