# FREQS A 0.315 C 0.185 G 0.185 T 0.315
    A   R   G   C   Y   T   K   M   S   W   N   X
A   8   2  -5 -15 -17 -18 -12  -3 -10  -5  -1 -30
R   0   1   3 -15 -16 -17  -7  -7  -5  -8  -1 -30
G  -8   2  11 -14 -15 -16  -2 -11  -1 -12  -1 -30
C -16 -15 -14  11   1  -8 -11  -2  -1 -12  -1 -30
Y -17 -16 -15   3   1   0  -7  -7  -5  -8  -1 -30
T -18 -17 -15  -5   1   8  -3 -12 -10  -5  -1 -30
K -13  -7  -1 -10  -6  -3  -2 -12  -5  -8  -1 -30
M  -3  -6 -10  -1  -7 -13 -11  -2  -5  -8  -1 -30
S -12  -7  -1  -1  -7 -12  -7  -7  -1 -12  -1 -30
W  -5  -7 -10 -10  -7  -5  -7  -7 -10  -5  -1 -30
N  -1  -1  -1  -1  -1  -1  -1  -1  -1  -1  -1 -30
X -30 -30 -30 -30 -30 -30 -30 -30 -30 -30 -30 -30