# FREQS A 0.325 C 0.175 G 0.175 T 0.325
    A   R   G   C   Y   T   K   M   S   W   N   X
A   8   2  -5 -15 -16 -18 -11  -3 -10  -5  -1 -29
R   1   1   3 -14 -16 -17  -7  -7  -5  -8  -1 -29
G  -8   2  11 -14 -15 -16  -2 -11  -1 -12  -1 -29
C -16 -15 -14  11   1  -8 -11  -2  -1 -12  -1 -29
Y -17 -16 -14   3   1   0  -7  -7  -5  -8  -1 -29
T -18 -16 -15  -5   1   8  -3 -11 -10  -5  -1 -29
K -13  -7  -1  -9  -6  -3  -2 -11  -5  -8  -1 -29
M  -3  -6  -9  -1  -7 -13 -11  -2  -5  -8  -1 -29
S -12  -6  -1  -1  -6 -12  -6  -6  -1 -12  -1 -29
W  -5  -7 -10 -10  -7  -5  -7  -7 -10  -5  -1 -29
N  -1  -1  -1  -1  -1  -1  -1  -1  -1  -1  -1 -29
X -29 -29 -29 -29 -29 -29 -29 -29 -29 -29 -29 -29