Use the GS De Novo Assembler to generate assembly results from 454 Sequencing data sets. Quick Start Documentation New Assembly Project Create a new Assembly project. Read Help Browse the help topics about using this application. Open an Assembly Project Open a previously created Assembly project. Support Open a browser and navigate to the Roche support site. Reopen a Recent Project Open one of the most recent projects you were working with. Click on the link to select a project from the list.