After an assembly has been performed on a project, the assembly computation can be repeated on that project, with the same Read Data or after addition or removal of one or more files, with the same assembly parameter settings or with different ones by pressing the Start button. If the “Incremental De Novo assembler analysis” checkbox on the Computation sub-tab of the Parameters tab is checked, this re-analysis will take much less time than the initial analysis, since only some data will be re-computed. Changes to some parameter settings (such as those on the Input and Computation sub-tabs of the Project Tab) will have no effect on reads already included in the prior assembly computation.