# species: Homo sapiens # support: EXP, IMP, ISS, ISM, TAS, IEA, IDA, IGI, ISO, IGC, NAS, IPI, IEP, ISA, RCA, IC # associations retrieved on: 2017-08-16 15:03:30-04 # gofunc built on: 2016-02-08 14:16:26.444801-05 # gene associations file: ftp://ftp.geneontology.org/pub/go/gene-associations/gene_association.goa_human.gz # revision: 12/09/2015 $ # downloaded on: 2015-12-22 08:03:12-05 # GO DAG files from: http://archive.geneontology.org/latest-full/go_201512-termdb-tables.tar.gz # downloaded on: 2015-12-22 05:43:21-05 # translation required: yes # translation info: # authority: ensembl # synergizer db built on: 2015-11-17 14:24:21.26681-05 # synergizer db built from: Ensembl Genes 82 / Metazoa Mart / Plant Mart # namespace: hgnc_symbol # coverage: 99.6% # size of "genespace": 18111 # number of attributes: 19424 # NOTE: the last record consists of all the entities in the # "genespace" that are not associated with any attribute (for # the requested support). # Original number of entities in query: 69 # Number of entities in query: 69 # Total number of entities: 18112 # Original total number of entities: 18111 # Entities not in default gene space: 1 # Total number of attributes: 19424 # Translation required: yes # Translation coverage: 0.995719 # Mode: unordered # Number of simulations: 1000 # Adjusted P-value cutoff: 0.05 # Over/under: over # Evidence codes: EXP, IMP, ISS, ISM, TAS, IEA, IDA, IGI, ISO, IGC, NAS, IPI, IEP, ISA, RCA, IC OVERREPRESENTED ATTRIBUTES N X LOD P P_adj attrib ID attrib name 7 12 2.59501897729769 6.64288499630241e-15 <0.001 GO:0005833 hemoglobin complex 7 14 2.46027224877987 2.86134823904846e-14 <0.001 GO:0005344 oxygen transporter activity 4 8 2.43998319606058 1.33461377542426e-08 <0.001 GO:0006782 protoporphyrinogen IX biosynthetic process 7 15 2.40589050714468 5.34893990750905e-14 <0.001 GO:0015671 oxygen transport 4 10 2.28023420124226 3.98085620309595e-08 <0.001 GO:0046501 protoporphyrinogen IX metabolic process 7 18 2.27453934655612 2.62156285321985e-13 <0.001 GO:0015669 gas transport 4 20 1.87542277380262 8.92435002304452e-07 0.001 GO:0006783 heme biosynthetic process 7 36 1.86498144266991 6.51506888738058e-11 <0.001 GO:0019825 oxygen binding 5 29 1.79737962662397 7.65978237390208e-08 <0.001 GO:0042168 heme metabolic process 4 25 1.76034778806356 2.29687119907362e-06 0.002 GO:0006779 porphyrin-containing compound biosynthetic process 4 28 1.70354786554855 3.6857767000849e-06 0.009 GO:0033014 tetrapyrrole biosynthetic process 5 37 1.67446949630519 2.74605673695375e-07 <0.001 GO:0006778 porphyrin-containing compound metabolic process 6 45 1.66892360087876 1.77397413484313e-08 <0.001 GO:0003954 NADH dehydrogenase activity 6 45 1.66892360087876 1.77397413484313e-08 <0.001 GO:0008137 NADH dehydrogenase (ubiquinone) activity 6 45 1.66892360087876 1.77397413484313e-08 <0.001 GO:0050136 NADH dehydrogenase (quinone) activity 5 45 1.57870489468789 7.51752423239228e-07 0.001 GO:0006120 mitochondrial electron transport, NADH to ubiquinone 5 46 1.56808769773982 8.4094858444081e-07 0.001 GO:0005747 mitochondrial respiratory chain complex I 5 46 1.56808769773982 8.4094858444081e-07 0.001 GO:0030964 NADH dehydrogenase complex 5 46 1.56808769773982 8.4094858444081e-07 0.001 GO:0045271 respiratory chain complex I 6 59 1.53682908294888 9.41171196077484e-08 <0.001 GO:0016655 oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor 6 61 1.5208415987398 1.15292328587327e-07 <0.001 GO:0098803 respiratory chain complex 5 58 1.45749242645697 2.71347907508008e-06 0.004 GO:0033013 tetrapyrrole metabolic process 5 59 1.44942556531873 2.95600956630087e-06 0.008 GO:0042440 pigment metabolic process 8 122 1.33530650182299 1.9938633690172e-08 <0.001 GO:0020037 heme binding 6 93 1.32235326818681 1.43854316882916e-06 0.001 GO:0016651 oxidoreductase activity, acting on NAD(P)H 6 96 1.30764017818054 1.73397141020755e-06 0.001 GO:0042542 response to hydrogen peroxide 8 131 1.30222697509182 3.48637019595302e-08 <0.001 GO:0046906 tetrapyrrole binding 6 100 1.28876017824814 2.20318191983633e-06 0.002 GO:0098800 inner mitochondrial membrane protein complex 9 159 1.27112702834581 8.9143046626293e-09 <0.001 GO:0005506 iron ion binding 7 126 1.25526039072286 5.02991348782402e-07 <0.001 GO:0022904 respiratory electron transport chain 7 128 1.24800355717137 5.59759060095928e-07 0.001 GO:0022900 electron transport chain 6 117 1.21650560347418 5.49511281034914e-06 0.01 GO:0072562 blood microparticle 6 126 1.18257540462466 8.42428963361342e-06 0.016 GO:0098798 mitochondrial protein complex 7 164 1.13442605479483 2.95564554142229e-06 0.008 GO:0044455 mitochondrial membrane part 7 167 1.12615872834904 3.3333222071996e-06 0.009 GO:0044445 cytosolic part 13 415 1.02005494500031 4.80441280511501e-09 <0.001 GO:0010035 response to inorganic substance 9 316 0.956991033762869 3.02241984268479e-06 0.008 GO:0006979 response to oxidative stress 8 289 0.940569501687037 1.37205891099867e-05 0.023 GO:0010038 response to metal ion 9 359 0.899093958729915 8.49047866912403e-06 0.016 GO:0042493 response to drug 10 410 0.890654554709558 3.27123277596286e-06 0.009 GO:0005743 mitochondrial inner membrane 10 442 0.856482568648088 6.35252547835957e-06 0.012 GO:0019866 organelle inner membrane 11 573 0.785998142020602 9.97013824576692e-06 0.019 GO:0031966 mitochondrial membrane 12 665 0.762308645127939 7.03683392065732e-06 0.013 GO:0016491 oxidoreductase activity 14 961 0.673403011082671 1.28046511013291e-05 0.023 GO:0055114 oxidation-reduction process 23 2056 0.599775627574231 1.07755620963157e-06 0.001 GO:0042221 response to chemical 24 2202 0.593450886844611 9.1402852551817e-07 0.001 GO:0044281 small molecule metabolic process