# hmmscan :: search sequence(s) against a profile database # HMMER 3.0 (March 2010); http://hmmer.org/ # Copyright (C) 2010 Howard Hughes Medical Institute. # Freely distributed under the GNU General Public License (GPLv3). # - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - # query sequence file: H1.5.fa # target HMM database: /N/dc2/projects/marinovg/genomes/PFam/PFam27.0/Pfam-A.hmm # output directed to file: H1.5.PFam-27-A # per-seq hits tabular output: H1.5.hmmscan.tblout # number of worker threads: 16 # - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - Query: histone_H1.5_[Homo_sapiens]gi|4885381|ref|NP_005313.1 [L=226] Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.1e-22 79.8 1.8 1.1e-22 79.8 1.3 2.1 2 Linker_histone linker histone H1 and H5 family Domain annotation for each model (and alignments): >> Linker_histone linker histone H1 and H5 family # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 79.8 1.3 7.6e-27 1.1e-22 3 77 .] 41 112 .. 39 112 .. 0.96 2 ? -3.3 1.5 0.64 9.4e+03 34 39 .. 149 154 .. 123 185 .. 0.58 Alignments for each domain: == domain 1 score: 79.8 bits; conditional E-value: 7.6e-27 --HHHHHHHHCCCCCCCTSEEHHHHHHHHHC.CTCCCCCSTTHHHHHHHHHHHHHH CS Linker_histone 3 ppyseMiveaikalkerkGsSvqaikKyiea.nykveinasnlasllklaLkkgvk 57 pp+se+i++a++a+ker+G S +a+kK ++a y+ve+n+ s++kl Lk++v+ histone_H1.5_[Homo_sapiens]gi|4885381|ref|NP_005313.1 41 PPVSELITKAVAASKERNGLSLAALKKALAAgGYDVEKNN----SRIKLGLKSLVS 92 9******************************889988888....************ PP CTSEE-TT..TTTSEEEESS CS Linker_histone 58 sGeLvqvkgtGasGsfklak 77 +G+Lvq+kgtGasGsfkl+k histone_H1.5_[Homo_sapiens]gi|4885381|ref|NP_005313.1 93 KGTLVQTKGTGASGSFKLNK 112 ******************97 PP == domain 2 score: -3.3 bits; conditional E-value: 0.64 CTCCCC CS Linker_histone 34 nykvei 39 + v++ histone_H1.5_[Homo_sapiens]gi|4885381|ref|NP_005313.1 149 KKAVKK 154 322222 PP Internal pipeline statistics summary: ------------------------------------- Query sequence(s): 1 (226 residues) Target model(s): 14831 (2610332 nodes) Passed MSV filter: 1050 (0.0707977); expected 296.6 (0.02) Passed bias filter: 290 (0.0195536); expected 296.6 (0.02) Passed Vit filter: 59 (0.00397815); expected 14.8 (0.001) Passed Fwd filter: 24 (0.00161823); expected 0.1 (1e-05) Initial search space (Z): 14831 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] # CPU time: 0.29u 0.45s 00:00:00.74 Elapsed: 00:00:01.94 # Mc/sec: 304.09 //