# --- full sequence ---- --- best 1 domain ---- --- domain number estimation ---- # target name accession query name accession E-value score bias E-value score bias exp reg clu ov env dom rep inc description of target #------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ ----- --- --- --- --- --- --- --- --- --------------------- Glyco_transf_49 PF13896.6 CBK19536.2 - 5.1e-21 75.4 7.1 1.2e-16 61.1 3.7 2.4 1 1 1 2 2 2 2 Glycosyl-transferase for dystroglycan PyrI_C PF02748.15 CBK19536.2 - 0.24 11.3 3.8 0.25 11.3 1.0 2.2 2 0 0 2 2 2 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain Ribosomal_L7Ae PF01248.26 CBK19539.2 - 0.0034 17.1 0.0 0.0062 16.2 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Cas9_C PF18525.1 CBK19539.2 - 0.14 12.3 0.0 0.2 11.9 0.0 1.1 1 0 0 1 1 1 0 Cas9 C-terminal domain RNase_P_pop3 PF08228.11 CBK19542.2 - 0.093 12.8 0.0 0.2 11.7 0.0 1.5 1 0 0 1 1 1 0 RNase P subunit Pop3 Glyco_transf_49 PF13896.6 CBK19543.2 - 2.8e-09 36.8 3.4 5.8e-09 35.7 0.4 2.4 2 1 0 2 2 2 1 Glycosyl-transferase for dystroglycan FBA_1 PF07734.13 CBK19543.2 - 0.00045 20.2 1.0 0.0015 18.5 0.5 2.0 1 1 1 2 2 2 2 F-box associated Pyr_redox_2 PF07992.14 CBK19544.2 - 3e-37 128.5 0.0 5e-37 127.7 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 CBK19544.2 - 1.2e-33 115.6 0.6 2e-33 114.9 0.6 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 CBK19544.2 - 1.5e-15 57.5 0.0 3.1e-15 56.5 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 CBK19544.2 - 2.7e-11 43.3 0.0 3.8e-11 42.8 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 CBK19544.2 - 0.073 11.8 0.0 0.64 8.6 0.0 2.0 2 0 0 2 2 2 0 HI0933-like protein Glyco_hydro_44 PF12891.7 CBK19545.2 - 0.026 14.4 0.0 0.041 13.8 0.0 1.2 1 0 0 1 1 1 0 Glycoside hydrolase family 44 DDDD PF10161.9 CBK19545.2 - 0.3 10.9 1.7 1.8 8.4 0.1 2.4 2 0 0 2 2 2 0 Putative mitochondrial precursor protein Glyco_transf_90 PF05686.12 CBK19546.2 - 0.092 11.6 0.0 0.14 11.0 0.0 1.2 1 0 0 1 1 1 0 Glycosyl transferase family 90 Pterin_bind PF00809.22 CBK19547.2 - 1.6e-88 296.6 0.9 2.3e-88 296.0 0.9 1.3 1 0 0 1 1 1 1 Pterin binding enzyme HPPK PF01288.20 CBK19547.2 - 5.2e-37 126.8 0.0 9.6e-37 125.9 0.0 1.5 1 0 0 1 1 1 1 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) Glutaredoxin PF00462.24 CBK19547.2 - 1.1e-17 64.0 0.0 3.7e-17 62.3 0.0 2.0 2 0 0 2 2 2 1 Glutaredoxin GST_N_2 PF13409.6 CBK19547.2 - 0.014 15.7 0.0 0.034 14.4 0.0 1.7 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain PEP_mutase PF13714.6 CBK19547.2 - 0.019 14.4 0.2 0.41 10.1 0.1 2.6 2 0 0 2 2 2 0 Phosphoenolpyruvate phosphomutase Thioredoxin_2 PF13098.6 CBK19547.2 - 0.094 13.2 0.1 0.47 10.9 0.0 2.2 3 0 0 3 3 3 0 Thioredoxin-like domain FYRN PF05964.14 CBK19548.2 - 2.3e-06 27.3 0.1 5.8e-06 26.1 0.1 1.7 1 0 0 1 1 1 1 F/Y-rich N-terminus FYRC PF05965.14 CBK19548.2 - 7.1e-06 26.1 0.0 1.5e-05 25.1 0.0 1.5 1 0 0 1 1 1 1 F/Y rich C-terminus DUF35_N PF12172.8 CBK19548.2 - 0.0024 17.7 2.3 0.0051 16.7 2.3 1.5 1 0 0 1 1 1 1 Rubredoxin-like zinc ribbon domain (DUF35_N) CpXC PF14353.6 CBK19548.2 - 0.26 11.3 1.6 11 6.1 0.2 2.5 2 0 0 2 2 2 0 CpXC protein zf-ribbon_3 PF13248.6 CBK19548.2 - 1.3 8.5 3.6 17 5.0 1.1 2.8 2 1 0 2 2 2 0 zinc-ribbon domain Cation_ATPase_C PF00689.21 CBK19549.2 - 1.4e-42 145.5 9.4 1.4e-42 145.5 9.4 2.1 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 CBK19549.2 - 2.8e-37 128.0 3.7 2.8e-37 128.0 3.7 2.4 3 0 0 3 3 3 1 E1-E2 ATPase Cation_ATPase PF13246.6 CBK19549.2 - 2.7e-16 59.4 0.0 6e-16 58.3 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 CBK19549.2 - 1.1e-14 55.2 0.0 5.3e-11 43.2 0.0 2.4 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 CBK19549.2 - 0.028 14.1 0.3 0.028 14.1 0.3 2.4 4 0 0 4 4 4 0 haloacid dehalogenase-like hydrolase RIBIOP_C PF04950.12 CBK19550.2 - 2e-77 260.5 0.0 2.2e-77 260.4 0.0 1.0 1 0 0 1 1 1 1 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal WD40 PF00400.32 CBK19552.2 - 5.3e-23 80.9 12.8 5.9e-07 30.1 0.0 5.4 5 0 0 5 5 5 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBK19552.2 - 4.9e-06 26.8 0.3 0.0069 16.7 0.0 3.2 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 CBK19552.2 - 0.017 13.8 0.0 0.99 8.0 0.0 2.1 2 0 0 2 2 2 0 Nucleoporin Nup120/160 Ala_racemase_N PF01168.20 CBK19553.2 - 3.2e-14 53.1 0.0 4e-14 52.8 0.0 1.1 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain D-ser_dehydrat PF14031.6 CBK19553.2 - 0.0031 18.1 0.0 0.016 15.9 0.0 2.0 2 1 0 2 2 2 1 Putative serine dehydratase domain Mito_fiss_reg PF05308.11 CBK19553.2 - 0.26 11.4 0.0 0.35 10.9 0.0 1.1 1 0 0 1 1 1 0 Mitochondrial fission regulator RRM_1 PF00076.22 CBK19554.2 - 2.5e-08 33.6 0.3 1.7e-07 31.0 0.0 2.5 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TPR_MLP1_2 PF07926.12 CBK19554.2 - 0.0012 18.8 4.4 0.0012 18.8 4.4 3.4 2 1 1 3 3 3 2 TPR/MLP1/MLP2-like protein CSTF2_hinge PF14327.6 CBK19554.2 - 0.041 14.3 0.0 0.12 12.9 0.0 1.7 1 0 0 1 1 1 0 Hinge domain of cleavage stimulation factor subunit 2 BRE1 PF08647.11 CBK19554.2 - 0.11 12.6 18.5 0.72 10.0 1.4 3.4 2 1 1 3 3 3 0 BRE1 E3 ubiquitin ligase MitMem_reg PF13012.6 CBK19554.2 - 0.19 12.1 2.7 1.2 9.6 0.2 2.9 3 0 0 3 3 3 0 Maintenance of mitochondrial structure and function LMBR1 PF04791.16 CBK19554.2 - 0.39 9.6 6.2 0.71 8.7 6.2 1.4 1 0 0 1 1 1 0 LMBR1-like membrane protein FapA PF03961.13 CBK19554.2 - 2 6.9 17.0 1.8 7.1 4.6 2.2 1 1 1 2 2 2 0 Flagellar Assembly Protein A POR_N PF01855.19 CBK19555.2 - 2.3e-64 217.3 0.2 3.8e-64 216.6 0.2 1.3 1 0 0 1 1 1 1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg POR PF01558.18 CBK19555.2 - 2.8e-28 99.2 0.0 5.6e-28 98.2 0.0 1.6 1 0 0 1 1 1 1 Pyruvate ferredoxin/flavodoxin oxidoreductase PFOR_II PF17147.4 CBK19555.2 - 2.3e-14 53.5 0.3 1.3e-13 51.1 0.1 2.4 2 0 0 2 2 2 1 Pyruvate:ferredoxin oxidoreductase core domain II EKR PF10371.9 CBK19555.2 - 4e-11 42.5 0.0 1.2e-10 41.0 0.0 1.9 1 0 0 1 1 1 1 Domain of unknown function TPP_enzyme_C PF02775.21 CBK19555.2 - 1.3e-08 34.8 1.2 5.8e-08 32.7 0.2 2.6 2 1 1 3 3 3 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Fer4_9 PF13187.6 CBK19555.2 - 3.1e-05 24.1 15.0 0.011 15.9 2.1 3.5 3 0 0 3 3 3 2 4Fe-4S dicluster domain Fer4_7 PF12838.7 CBK19555.2 - 6e-05 23.5 20.0 0.00011 22.8 14.3 3.4 2 1 2 4 4 4 3 4Fe-4S dicluster domain Fer4 PF00037.27 CBK19555.2 - 8.2e-05 22.2 12.3 0.00076 19.2 1.6 4.1 4 0 0 4 4 4 2 4Fe-4S binding domain Fer4_16 PF13484.6 CBK19555.2 - 0.00014 22.7 17.1 0.003 18.5 2.7 3.5 3 0 0 3 3 3 2 4Fe-4S double cluster binding domain Fer4_8 PF13183.6 CBK19555.2 - 0.00067 20.1 12.7 0.025 15.0 10.2 3.0 2 1 0 2 2 2 1 4Fe-4S dicluster domain Fer4_10 PF13237.6 CBK19555.2 - 0.0011 19.0 15.2 0.15 12.2 0.7 3.7 3 0 0 3 3 3 2 4Fe-4S dicluster domain Fer4_21 PF14697.6 CBK19555.2 - 0.01 15.9 13.1 0.01 15.9 13.1 3.2 2 1 0 2 2 2 0 4Fe-4S dicluster domain Transketolase_C PF02780.20 CBK19555.2 - 0.015 15.2 0.0 0.082 12.8 0.0 2.1 2 0 0 2 2 2 0 Transketolase, C-terminal domain Fer4_17 PF13534.6 CBK19555.2 - 0.045 14.3 19.1 0.096 13.2 11.9 3.3 2 1 0 2 2 2 0 4Fe-4S dicluster domain Fer4_6 PF12837.7 CBK19555.2 - 0.048 13.7 30.3 0.03 14.4 4.9 4.5 4 0 0 4 4 4 0 4Fe-4S binding domain Pyr_redox PF00070.27 CBK19555.2 - 0.22 12.1 0.6 18 6.0 0.0 3.2 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Fer4_18 PF13746.6 CBK19555.2 - 1.5 9.0 9.2 2.3 8.4 0.2 3.1 3 0 0 3 3 3 0 4Fe-4S dicluster domain SH3_9 PF14604.6 CBK19556.2 - 4.3e-17 61.7 0.2 1.5e-15 56.7 0.1 2.4 2 0 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.28 CBK19556.2 - 3.6e-15 55.3 0.1 8.5e-15 54.1 0.1 1.7 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 CBK19556.2 - 3.6e-12 45.8 0.0 9.1e-12 44.5 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain BAR PF03114.18 CBK19556.2 - 7.5e-08 32.3 6.7 1.3e-06 28.3 6.9 2.5 1 1 1 2 2 2 1 BAR domain BAR_3 PF16746.5 CBK19556.2 - 0.00076 19.3 2.7 0.0012 18.6 2.7 1.3 1 0 0 1 1 1 1 BAR domain of APPL family WbqC PF08889.11 CBK19556.2 - 0.0056 16.6 1.5 0.16 11.8 0.2 2.2 2 0 0 2 2 2 1 WbqC-like protein family DUF3037 PF11236.8 CBK19556.2 - 0.04 14.3 0.7 0.13 12.7 0.2 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF3037) Sec34 PF04136.15 CBK19556.2 - 0.079 12.8 1.5 0.15 12.0 0.2 2.2 2 1 1 3 3 3 0 Sec34-like family Rtt106 PF08512.12 CBK19557.2 - 3.5e-12 46.6 0.1 1.8e-11 44.3 0.0 1.9 2 0 0 2 2 2 1 Histone chaperone Rttp106-like HLH PF00010.26 CBK19558.2 - 2.4e-13 49.8 3.0 2.9e-13 49.6 1.2 2.2 3 0 0 3 3 3 1 Helix-loop-helix DNA-binding domain GATase_7 PF13537.6 CBK19558.2 - 1.4e-09 37.9 0.0 8.4e-09 35.4 0.0 2.1 1 1 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.6 CBK19558.2 - 4.1e-05 23.8 0.0 9.2e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain Asn_synthase PF00733.21 CBK19558.2 - 0.024 14.3 0.1 0.036 13.7 0.1 1.2 1 0 0 1 1 1 0 Asparagine synthase PAS_9 PF13426.7 CBK19558.2 - 0.043 14.1 0.0 0.13 12.5 0.0 1.8 1 0 0 1 1 1 0 PAS domain Paramyx_P_V_C PF03210.13 CBK19558.2 - 0.043 13.6 0.1 0.079 12.8 0.1 1.4 1 0 0 1 1 1 0 Paramyxovirus P/V phosphoprotein C-terminal NPV_P10 PF05531.12 CBK19558.2 - 0.26 11.8 0.9 9.1 6.8 0.0 2.8 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein Asn_synthase PF00733.21 CBK19559.2 - 0.022 14.4 0.0 0.022 14.4 0.0 1.1 1 0 0 1 1 1 0 Asparagine synthase PUF PF00806.19 CBK19560.2 - 4e-37 123.8 2.4 1.9e-05 24.1 0.0 7.5 7 0 0 7 7 7 7 Pumilio-family RNA binding repeat CPL PF08144.11 CBK19560.2 - 0.0002 21.7 0.7 5.9 7.2 0.0 4.1 2 1 2 4 4 4 3 CPL (NUC119) domain DUF3683 PF12447.8 CBK19560.2 - 0.13 12.4 0.8 0.63 10.2 0.2 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF3683) PLN_propep PF16485.5 CBK19560.2 - 0.16 11.7 1.1 20 5.0 0.0 3.3 3 0 0 3 3 3 0 Protealysin propeptide Aph-1 PF06105.12 CBK19561.2 - 2.5e-40 138.3 22.1 3e-40 138.1 22.1 1.0 1 0 0 1 1 1 1 Aph-1 protein TPR_8 PF13181.6 CBK19562.2 - 0.0014 18.7 1.6 20 5.7 0.0 4.6 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.28 CBK19562.2 - 0.0033 17.2 0.7 5.4 7.0 0.0 3.7 4 0 0 4 4 4 2 Tetratricopeptide repeat ANAPC3 PF12895.7 CBK19562.2 - 0.0078 16.4 1.0 2.5 8.4 0.0 3.7 3 1 0 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.17 CBK19562.2 - 0.018 15.1 1.1 10 6.5 0.2 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_19 PF14559.6 CBK19562.2 - 0.027 15.0 0.6 45 4.6 0.0 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF1282 PF06930.12 CBK19562.2 - 0.033 14.0 1.1 0.071 12.9 0.5 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1282) TPR_10 PF13374.6 CBK19562.2 - 0.25 11.3 1.7 61 3.7 0.1 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.17 CBK19563.2 - 0.0063 16.5 0.1 1.2 9.4 0.0 3.2 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.6 CBK19563.2 - 0.0085 16.7 0.2 0.53 11.0 0.0 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.6 CBK19563.2 - 0.0093 15.6 4.8 0.21 11.3 0.2 3.0 3 0 0 3 3 3 2 TPR repeat TPR_1 PF00515.28 CBK19563.2 - 0.057 13.3 1.8 3.5 7.6 0.1 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_16 PF13432.6 CBK19563.2 - 0.099 13.3 0.0 0.22 12.2 0.0 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat FAM176 PF14851.6 CBK19564.2 - 0.2 11.3 6.7 3.2 7.4 1.0 2.1 1 1 1 2 2 2 0 FAM176 family WD40 PF00400.32 CBK19572.2 - 7.3e-15 55.1 9.5 6e-08 33.2 0.4 5.3 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBK19572.2 - 6.9e-10 39.1 0.0 0.18 12.1 0.0 4.3 3 1 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 CBK19572.2 - 0.061 13.2 0.1 20 5.0 0.1 3.1 2 1 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A TAF PF02969.17 CBK19573.2 - 2.8e-05 24.2 0.2 5.4e-05 23.3 0.2 1.4 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) Histone PF00125.24 CBK19573.2 - 0.044 14.1 0.4 0.097 13.0 0.4 1.6 1 0 0 1 1 1 0 Core histone H2A/H2B/H3/H4 TFIID-31kDa PF02291.15 CBK19573.2 - 0.049 13.7 0.0 0.096 12.8 0.0 1.5 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit EF-hand_6 PF13405.6 CBK19574.2 - 4.4e-15 54.2 5.2 0.00052 19.7 0.0 4.2 4 0 0 4 4 4 4 EF-hand domain EF-hand_7 PF13499.6 CBK19574.2 - 4.2e-14 52.7 3.9 9e-08 32.5 0.3 3.1 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_1 PF00036.32 CBK19574.2 - 1.2e-12 46.3 2.3 2.3e-05 23.6 0.1 4.0 4 0 0 4 4 4 2 EF hand EF-hand_8 PF13833.6 CBK19574.2 - 1.7e-05 24.6 3.6 0.13 12.1 0.1 3.5 4 0 0 4 4 4 2 EF-hand domain pair EF-hand_5 PF13202.6 CBK19574.2 - 3.1e-05 23.3 4.3 0.15 11.6 0.0 4.5 5 0 0 5 5 5 2 EF hand EF-hand_10 PF14788.6 CBK19574.2 - 0.036 13.9 0.8 1.4 8.8 0.1 2.6 2 0 0 2 2 2 0 EF hand YppF PF14178.6 CBK19574.2 - 0.063 13.2 0.4 1.9 8.4 0.0 3.0 3 1 0 4 4 4 0 YppF-like protein PMBR PF09373.10 CBK19574.2 - 0.12 12.5 0.3 0.97 9.7 0.0 2.5 3 0 0 3 3 3 0 Pseudomurein-binding repeat HEAT PF02985.22 CBK19576.2 - 0.0012 18.9 0.6 0.18 12.2 0.0 3.4 3 0 0 3 3 3 2 HEAT repeat Raptor_N PF14538.6 CBK19577.2 - 3.6e-30 104.9 0.0 6e-30 104.1 0.0 1.3 1 0 0 1 1 1 1 Raptor N-terminal CASPase like domain Peptidase_C14 PF00656.22 CBK19577.2 - 0.0012 18.8 0.0 0.0017 18.3 0.0 1.2 1 0 0 1 1 1 1 Caspase domain Fer4 PF00037.27 CBK19579.2 - 1.7e-13 49.8 15.8 6.1e-09 35.3 3.4 2.4 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.7 CBK19579.2 - 1.8e-12 47.6 8.0 4.4e-12 46.4 8.0 1.7 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_10 PF13237.6 CBK19579.2 - 6.4e-11 42.2 18.9 3.6e-07 30.2 11.2 2.2 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_9 PF13187.6 CBK19579.2 - 6.8e-10 39.0 8.0 1.7e-09 37.7 8.0 1.7 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_16 PF13484.6 CBK19579.2 - 1.1e-09 39.0 3.8 0.00015 22.7 0.1 2.4 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_21 PF14697.6 CBK19579.2 - 1.5e-08 34.6 4.8 0.0012 19.0 1.3 2.5 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_8 PF13183.6 CBK19579.2 - 5.6e-08 33.1 4.1 0.00043 20.7 0.1 2.3 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_6 PF12837.7 CBK19579.2 - 1.9e-07 30.8 16.8 0.00025 21.0 5.1 2.4 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_2 PF12797.7 CBK19579.2 - 1.1e-06 28.4 11.8 0.0036 17.3 2.7 2.6 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_4 PF12800.7 CBK19579.2 - 7.6e-06 26.0 11.0 0.00038 20.7 1.8 2.7 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_17 PF13534.6 CBK19579.2 - 0.00018 22.0 12.6 0.0068 16.9 11.3 2.4 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_3 PF12798.7 CBK19579.2 - 0.0032 18.3 16.3 0.019 15.8 4.0 2.8 2 0 0 2 2 2 2 4Fe-4S binding domain c-SKI_SMAD_bind PF08782.10 CBK19579.2 - 0.0066 16.6 6.1 0.42 10.9 1.2 2.5 1 1 1 2 2 2 2 c-SKI Smad4 binding domain Fer4_13 PF13370.6 CBK19579.2 - 0.0085 16.6 13.8 0.37 11.4 2.0 2.4 2 0 0 2 2 2 2 4Fe-4S single cluster domain of Ferredoxin I Fer4_18 PF13746.6 CBK19579.2 - 0.083 13.1 9.7 6.5 7.0 1.2 2.3 1 1 1 2 2 2 0 4Fe-4S dicluster domain ETF_QO PF05187.13 CBK19579.2 - 0.73 10.0 4.5 1.3 9.1 2.9 1.9 1 1 1 2 2 2 0 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S Fer4_22 PF17179.4 CBK19579.2 - 1.6 9.6 12.2 3 8.8 1.6 2.4 1 1 2 3 3 2 0 4Fe-4S dicluster domain Fer4_15 PF13459.6 CBK19579.2 - 2.7 8.8 12.1 12 6.7 4.9 3.0 2 1 0 2 2 2 0 4Fe-4S single cluster domain RCC1 PF00415.18 CBK19580.2 - 0.00028 21.5 0.2 0.91 10.2 0.0 2.8 2 2 0 2 2 2 2 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 CBK19580.2 - 0.038 13.8 0.0 3.5 7.5 0.0 2.6 3 0 0 3 3 3 0 Regulator of chromosome condensation (RCC1) repeat TPR_10 PF13374.6 CBK19580.2 - 0.063 13.2 0.2 0.13 12.1 0.2 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat Metallophos PF00149.28 CBK19581.2 - 1.2e-11 45.5 0.0 1.5e-11 45.2 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 CBK19581.2 - 3.9e-06 27.2 0.0 8.6e-06 26.0 0.0 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos_3 PF14582.6 CBK19581.2 - 3.6e-05 23.2 0.0 4.4e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 Metallophosphoesterase, calcineurin superfamily Ala_racemase_N PF01168.20 CBK19581.2 - 0.16 11.6 0.0 0.79 9.3 0.0 1.9 2 0 0 2 2 2 0 Alanine racemase, N-terminal domain DAGAT PF03982.13 CBK19582.2 - 6.6e-23 81.1 0.0 1.7e-22 79.7 0.0 1.6 1 1 0 1 1 1 1 Diacylglycerol acyltransferase MgtE PF01769.16 CBK19582.2 - 0.3 11.5 4.0 0.58 10.5 4.0 1.4 1 0 0 1 1 1 0 Divalent cation transporter Steroid_dh PF02544.16 CBK19583.2 - 1.2e-53 181.2 1.4 1.2e-53 181.2 1.4 1.8 2 1 0 2 2 2 1 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1295 PF06966.12 CBK19583.2 - 2.9e-06 27.0 1.4 3.7e-06 26.6 0.3 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1295) TadE PF07811.12 CBK19583.2 - 0.65 10.3 0.1 0.65 10.3 0.1 2.9 4 0 0 4 4 4 0 TadE-like protein BP28CT PF08146.12 CBK19584.2 - 7.4e-32 110.4 2.6 2.1e-31 108.9 0.5 3.1 3 0 0 3 3 3 1 BP28CT (NUC211) domain U3snoRNP10 PF12397.8 CBK19584.2 - 4.3e-10 39.9 1.9 4.3e-10 39.9 1.9 7.4 7 2 1 8 8 8 1 U3 small nucleolar RNA-associated protein 10 HEAT_2 PF13646.6 CBK19584.2 - 0.15 12.5 2.8 3.9 7.9 0.1 4.0 4 0 0 4 4 4 0 HEAT repeats AI-2E_transport PF01594.16 CBK19584.2 - 0.57 9.3 6.4 0.37 9.9 0.0 3.4 4 0 0 4 4 4 0 AI-2E family transporter HEAT_EZ PF13513.6 CBK19584.2 - 0.74 10.4 6.5 0.73 10.4 0.1 4.2 4 0 0 4 4 4 0 HEAT-like repeat SAM_decarbox PF01536.16 CBK19585.2 - 1.8e-78 264.0 0.0 2.9e-78 263.4 0.0 1.3 1 0 0 1 1 1 1 Adenosylmethionine decarboxylase PPTA PF01239.22 CBK19585.2 - 5.6e-28 95.8 11.4 3.1e-10 39.5 0.1 4.7 4 0 0 4 4 4 4 Protein prenyltransferase alpha subunit repeat PWI PF01480.17 CBK19586.2 - 0.032 14.6 0.0 0.073 13.4 0.0 1.6 1 0 0 1 1 1 0 PWI domain OST3_OST6 PF04756.13 CBK19587.2 - 4.7e-42 144.3 0.0 6e-42 144.0 0.0 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family L6_membrane PF05805.12 CBK19587.2 - 0.25 10.9 2.6 2.8 7.5 0.2 2.4 1 1 1 2 2 2 0 L6 membrane protein BRCA2 PF00634.18 CBK19588.2 - 8.5e-121 393.3 64.7 7.1e-06 25.6 0.3 21.6 17 3 4 21 21 21 20 BRCA2 repeat BRCA-2_OB1 PF09103.10 CBK19588.2 - 8.7e-24 83.8 0.0 4.6e-23 81.5 0.0 2.4 1 1 0 1 1 1 1 BRCA2, oligonucleotide/oligosaccharide-binding, domain 1 BRCA-2_helical PF09169.10 CBK19588.2 - 3.6e-06 26.8 0.3 1.1e-05 25.1 0.2 1.9 1 1 0 1 1 1 1 BRCA2, helical DUF4088 PF13317.6 CBK19588.2 - 9.5 5.7 12.1 1.1e+02 2.2 0.2 5.8 1 1 3 6 6 6 0 Protein of unknown function (DUF4088) Lung_7-TM_R PF06814.13 CBK19589.2 - 2.3e-41 142.0 23.8 2.6e-41 141.8 23.8 1.0 1 0 0 1 1 1 1 Lung seven transmembrane receptor GpcrRhopsn4 PF10192.9 CBK19589.2 - 0.036 13.5 25.6 0.0082 15.6 22.0 1.6 1 1 1 2 2 2 0 Rhodopsin-like GPCR transmembrane domain Bac_export_2 PF01312.19 CBK19589.2 - 0.19 10.9 11.0 0.31 10.2 11.0 1.3 1 0 0 1 1 1 0 FlhB HrpN YscU SpaS Family Adap_comp_sub PF00928.21 CBK19592.2 - 6.5e-59 199.4 0.1 9.1e-59 199.0 0.1 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 CBK19592.2 - 2.4e-05 24.3 0.0 4.3e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain BRK PF07533.16 CBK19592.2 - 0.13 12.0 0.0 0.4 10.3 0.0 1.8 2 0 0 2 2 2 0 BRK domain RIFIN PF02009.16 CBK19593.2 - 0.095 12.6 0.4 0.16 11.8 0.4 1.3 1 0 0 1 1 1 0 Rifin ABC2_membrane PF01061.24 CBK19594.2 - 2.3e-06 27.2 3.3 3.1e-06 26.8 3.3 1.1 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.27 CBK19595.2 - 0.0012 19.3 0.0 0.0023 18.5 0.0 1.4 1 0 0 1 1 1 1 ABC transporter RPOL_N PF14700.6 CBK19596.2 - 1.9e-21 76.9 0.0 2.5e-21 76.5 0.0 1.1 1 0 0 1 1 1 1 DNA-directed RNA polymerase N-terminal RNA_pol PF00940.19 CBK19597.2 - 6.9e-159 529.1 0.0 2e-158 527.6 0.0 1.7 1 1 0 1 1 1 1 DNA-dependent RNA polymerase RPOL_N PF14700.6 CBK19597.2 - 4.7e-21 75.5 0.0 6.8e-21 75.0 0.0 1.2 1 0 0 1 1 1 1 DNA-directed RNA polymerase N-terminal Epimerase PF01370.21 CBK19598.2 - 7.2e-26 91.1 0.0 9.6e-26 90.7 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 CBK19598.2 - 3e-24 86.0 0.1 3.1e-23 82.7 0.1 2.1 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 CBK19598.2 - 1.2e-13 50.8 0.0 1.8e-13 50.2 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain 3Beta_HSD PF01073.19 CBK19598.2 - 4.7e-11 42.2 0.0 6.8e-11 41.7 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 CBK19598.2 - 2.1e-09 36.9 0.0 2.9e-08 33.2 0.0 2.5 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.12 CBK19598.2 - 3e-05 23.3 0.0 0.0002 20.6 0.0 2.2 2 1 0 2 2 2 1 Male sterility protein NAD_binding_10 PF13460.6 CBK19598.2 - 0.051 13.5 0.0 0.076 12.9 0.0 1.2 1 0 0 1 1 1 0 NAD(P)H-binding Prefoldin_2 PF01920.20 CBK19599.2 - 4.8e-05 23.3 0.1 5e-05 23.2 0.1 1.1 1 0 0 1 1 1 1 Prefoldin subunit WD40 PF00400.32 CBK19600.2 - 7.9e-38 127.8 22.7 8.6e-08 32.7 0.3 11.9 12 0 0 12 12 12 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBK19600.2 - 8.1e-26 90.2 0.1 0.02 15.2 0.0 9.0 3 2 5 9 9 9 6 Anaphase-promoting complex subunit 4 WD40 domain Utp12 PF04003.12 CBK19600.2 - 1.5e-18 67.0 0.1 2.4e-18 66.4 0.1 1.3 1 0 0 1 1 1 1 Dip2/Utp12 Family Ge1_WD40 PF16529.5 CBK19600.2 - 1.1e-05 24.6 0.2 2.5 7.0 0.0 4.8 4 2 1 5 5 5 3 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 CBK19600.2 - 7e-05 22.8 0.3 1.2 8.9 0.0 5.0 4 2 2 6 6 6 2 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 CBK19600.2 - 0.0014 18.0 0.0 0.31 10.3 0.0 3.4 4 0 0 4 4 4 1 WD40-like domain Caldesmon PF02029.15 CBK19600.2 - 0.1 11.3 50.2 0.15 10.8 50.2 1.1 1 0 0 1 1 1 0 Caldesmon BUD22 PF09073.10 CBK19600.2 - 0.76 9.1 53.0 1.1 8.5 53.0 1.1 1 0 0 1 1 1 0 BUD22 DUF4045 PF13254.6 CBK19600.2 - 1.1 8.9 30.7 1.5 8.3 30.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) Hid1 PF12722.7 CBK19600.2 - 1.4 7.0 26.0 1.9 6.5 26.0 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Presenilin PF01080.17 CBK19600.2 - 3.7 6.2 32.9 5.7 5.6 32.9 1.1 1 0 0 1 1 1 0 Presenilin Ribosomal_S17 PF00366.20 CBK19601.2 - 5.7e-28 96.8 0.4 9.5e-28 96.1 0.4 1.4 1 0 0 1 1 1 1 Ribosomal protein S17 Ribosomal_S17_N PF16205.5 CBK19601.2 - 3.1e-25 88.3 0.3 3.1e-25 88.3 0.3 1.6 2 0 0 2 2 2 1 Ribosomal_S17 N-terminal Syndecan PF01034.20 CBK19602.2 - 0.86 9.6 2.8 1.4 8.8 2.8 1.3 1 0 0 1 1 1 0 Syndecan domain GAPT PF11770.8 CBK19602.2 - 5.3 6.9 5.1 48 3.8 2.2 2.4 2 1 1 3 3 3 0 GRB2-binding adapter (GAPT) DUF1295 PF06966.12 CBK19604.2 - 9e-32 110.5 11.0 1.1e-31 110.1 11.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) DUF1634 PF07843.11 CBK19604.2 - 0.051 13.6 2.8 6.1 7.0 0.2 2.9 3 1 0 3 3 3 0 Protein of unknown function (DUF1634) Glyco_transf_41 PF13844.6 CBK19605.2 - 4.3e-48 163.9 0.1 9.5e-30 103.4 0.0 2.0 1 1 1 2 2 2 2 Glycosyl transferase family 41 Cyclin_C PF02984.19 CBK19606.2 - 1.8e-07 31.2 0.6 2.6e-07 30.8 0.6 1.3 1 0 0 1 1 1 1 Cyclin, C-terminal domain Cyclin_N PF00134.23 CBK19606.2 - 0.0054 16.5 0.5 0.29 10.9 0.1 2.3 2 0 0 2 2 2 2 Cyclin, N-terminal domain AAA PF00004.29 CBK19607.2 - 4.2e-77 257.0 0.0 5.7e-48 162.7 0.0 2.2 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CBK19607.2 - 7.9e-14 51.2 2.8 1.3e-11 44.1 0.1 4.1 4 2 1 5 5 4 1 AAA+ lid domain Vps4_C PF09336.10 CBK19607.2 - 2.9e-10 40.0 0.0 0.00034 20.5 0.0 2.9 2 0 0 2 2 2 2 Vps4 C terminal oligomerisation domain RuvB_N PF05496.12 CBK19607.2 - 2.4e-08 33.9 0.0 0.00011 22.0 0.0 2.7 3 0 0 3 3 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 CBK19607.2 - 2.8e-07 30.8 0.0 8.8e-05 22.7 0.0 2.5 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 CBK19607.2 - 1.4e-06 28.3 0.3 0.0033 17.4 0.1 3.3 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 CBK19607.2 - 2.2e-06 28.1 0.0 0.0011 19.4 0.0 3.5 2 2 1 3 3 3 1 AAA ATPase domain AAA_22 PF13401.6 CBK19607.2 - 2.5e-06 27.8 0.1 0.015 15.5 0.0 3.5 3 1 0 3 3 2 1 AAA domain AAA_14 PF13173.6 CBK19607.2 - 3.2e-05 24.0 0.0 0.0033 17.5 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 CBK19607.2 - 0.0011 18.6 0.8 1.3 8.6 0.1 2.7 3 0 0 3 3 3 2 AAA domain AAA_33 PF13671.6 CBK19607.2 - 0.0029 17.8 0.0 0.048 13.8 0.0 2.3 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 CBK19607.2 - 0.0031 17.9 0.0 0.047 14.1 0.0 2.6 3 0 0 3 3 2 1 RNA helicase Sigma54_activat PF00158.26 CBK19607.2 - 0.0064 16.2 0.0 0.067 12.9 0.0 2.6 2 1 0 2 2 2 1 Sigma-54 interaction domain Mg_chelatase PF01078.21 CBK19607.2 - 0.012 15.0 0.1 0.026 13.9 0.1 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI TIP49 PF06068.13 CBK19607.2 - 0.016 14.4 0.0 0.057 12.6 0.0 1.8 2 0 0 2 2 2 0 TIP49 P-loop domain ATPase PF06745.13 CBK19607.2 - 0.019 14.3 0.1 0.26 10.6 0.0 2.2 2 0 0 2 2 2 0 KaiC Zeta_toxin PF06414.12 CBK19607.2 - 0.02 14.2 0.0 0.045 13.0 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin AAA_18 PF13238.6 CBK19607.2 - 0.022 15.3 0.0 0.079 13.5 0.0 1.9 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 CBK19607.2 - 0.031 14.8 0.0 0.071 13.6 0.0 1.7 1 0 0 1 1 1 0 ABC transporter IstB_IS21 PF01695.17 CBK19607.2 - 0.035 13.9 0.0 0.087 12.6 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein ATPase_2 PF01637.18 CBK19607.2 - 0.045 13.7 0.0 0.29 11.0 0.0 2.0 1 1 1 2 2 2 0 ATPase domain predominantly from Archaea NB-ARC PF00931.22 CBK19607.2 - 0.051 12.8 0.0 0.19 10.9 0.0 1.9 2 0 0 2 2 2 0 NB-ARC domain AAA_7 PF12775.7 CBK19607.2 - 0.067 12.7 0.0 0.16 11.4 0.0 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_24 PF13479.6 CBK19607.2 - 0.068 12.9 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain Sigma54_activ_2 PF14532.6 CBK19607.2 - 0.11 12.6 0.0 0.91 9.6 0.0 2.3 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_28 PF13521.6 CBK19607.2 - 0.13 12.5 0.0 0.3 11.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.15 CBK19607.2 - 0.14 12.0 0.0 0.37 10.7 0.0 1.7 2 0 0 2 2 2 0 Rad17 P-loop domain NACHT PF05729.12 CBK19607.2 - 0.15 12.0 0.0 0.74 9.7 0.0 2.1 2 0 0 2 2 2 0 NACHT domain TsaE PF02367.17 CBK19607.2 - 0.18 11.8 0.0 0.31 11.0 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ODV-E18 PF10717.9 CBK19608.2 - 0.0011 18.7 0.1 0.0023 17.8 0.1 1.5 1 0 0 1 1 1 1 Occlusion-derived virus envelope protein ODV-E18 TRP PF06011.12 CBK19608.2 - 0.0021 16.9 0.1 0.0025 16.6 0.1 1.0 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel Phage_holin_3_6 PF07332.11 CBK19608.2 - 0.017 15.2 0.5 0.024 14.7 0.5 1.2 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III DUF5385 PF17359.2 CBK19608.2 - 0.031 13.8 1.9 0.05 13.2 1.9 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5385) YodL PF14191.6 CBK19608.2 - 0.052 14.4 0.0 0.084 13.7 0.0 1.3 1 0 0 1 1 1 0 YodL-like Tail_tube PF10618.9 CBK19608.2 - 0.063 13.2 0.1 0.1 12.5 0.1 1.4 1 0 0 1 1 1 0 Phage tail tube protein Pox_EPC_I2-L1 PF12575.8 CBK19608.2 - 0.071 13.3 1.7 0.13 12.5 1.7 1.4 1 0 0 1 1 1 0 Poxvirus entry protein complex L1 and I2 RBP_receptor PF14752.6 CBK19608.2 - 0.14 10.7 0.2 0.15 10.6 0.2 1.1 1 0 0 1 1 1 0 Retinol binding protein receptor OAD_gamma PF04277.13 CBK19608.2 - 0.19 12.4 0.4 0.19 12.4 0.4 1.5 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain SecG PF03840.14 CBK19608.2 - 5.9 7.1 10.5 0.38 10.9 4.0 2.3 2 1 1 3 3 3 0 Preprotein translocase SecG subunit SHMT PF00464.19 CBK19609.2 - 3e-175 582.6 0.0 3.5e-175 582.4 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Beta_elim_lyase PF01212.21 CBK19609.2 - 0.00027 20.3 0.0 0.00051 19.4 0.0 1.5 1 0 0 1 1 1 1 Beta-eliminating lyase SHMT PF00464.19 CBK19610.2 - 3.5e-175 582.4 0.0 4.2e-175 582.1 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Beta_elim_lyase PF01212.21 CBK19610.2 - 0.0003 20.2 0.0 0.00057 19.2 0.0 1.5 1 0 0 1 1 1 1 Beta-eliminating lyase LRR_8 PF13855.6 CBK19611.2 - 0.0088 15.8 0.2 0.38 10.5 0.0 2.9 2 1 1 3 3 3 1 Leucine rich repeat DHHC PF01529.20 CBK19612.2 - 5.8e-06 26.4 22.1 0.00011 22.3 22.1 2.0 1 1 0 1 1 1 1 DHHC palmitoyltransferase ADH_N PF08240.12 CBK19612.2 - 0.011 15.6 0.7 0.013 15.3 0.7 1.2 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-like domain RecR PF02132.15 CBK19612.2 - 0.012 15.2 2.6 0.027 14.0 2.6 1.5 1 0 0 1 1 1 0 RecR protein FH2 PF02181.23 CBK19613.2 - 0.0025 17.0 0.1 0.0031 16.7 0.1 1.0 1 0 0 1 1 1 1 Formin Homology 2 Domain YtxH PF12732.7 CBK19613.2 - 0.0064 17.0 0.9 0.0088 16.6 0.9 1.2 1 0 0 1 1 1 1 YtxH-like protein WXG100 PF06013.12 CBK19613.2 - 0.0089 16.2 0.2 0.011 16.0 0.2 1.1 1 0 0 1 1 1 1 Proteins of 100 residues with WXG ApoLp-III PF07464.11 CBK19613.2 - 0.012 15.8 0.4 0.016 15.3 0.4 1.2 1 0 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) Sec8_exocyst PF04048.14 CBK19613.2 - 0.019 14.8 0.8 0.027 14.3 0.8 1.3 1 1 0 1 1 1 0 Sec8 exocyst complex component specific domain DUF2990 PF11693.8 CBK19613.2 - 0.039 14.1 0.9 1.6 9.0 0.1 2.1 1 1 0 2 2 2 0 Protein of unknown function (DUF2990) Tape_meas_lam_C PF09718.10 CBK19613.2 - 0.36 11.0 3.3 2.1 8.5 3.3 1.9 1 1 0 1 1 1 0 Lambda phage tail tape-measure protein (Tape_meas_lam_C) Pkinase PF00069.25 CBK19614.2 - 2.3e-78 263.2 0.0 2.6e-78 263.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBK19614.2 - 2.7e-43 148.1 0.0 3.3e-43 147.8 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CBK19614.2 - 2.7e-06 26.9 0.0 4.5e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.22 CBK19614.2 - 4.7e-05 23.1 0.2 7.6e-05 22.4 0.2 1.2 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.14 CBK19614.2 - 0.00039 19.8 0.1 0.00053 19.4 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 CBK19614.2 - 0.00063 18.8 0.1 0.0013 17.7 0.1 1.4 2 0 0 2 2 2 1 Haspin like kinase domain APH PF01636.23 CBK19614.2 - 0.0048 16.8 0.1 0.042 13.8 0.1 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family YukC PF10140.9 CBK19614.2 - 0.12 11.2 0.3 0.4 9.5 0.0 1.7 1 1 1 2 2 2 0 WXG100 protein secretion system (Wss), protein YukC Glyco_transf_92 PF01697.27 CBK19615.2 - 3e-13 50.0 0.5 3e-13 50.0 0.5 1.6 2 0 0 2 2 2 1 Glycosyltransferase family 92 Glyco_tranf_2_4 PF13704.6 CBK19615.2 - 0.0099 16.4 0.1 0.19 12.3 0.0 2.7 3 0 0 3 3 3 1 Glycosyl transferase family 2 Lon_C PF05362.13 CBK19616.2 - 1.1e-70 237.3 0.0 5e-59 199.3 0.0 2.9 3 0 0 3 3 3 2 Lon protease (S16) C-terminal proteolytic domain AAA PF00004.29 CBK19616.2 - 7.8e-24 84.6 0.0 2.4e-23 83.0 0.0 1.9 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) ChlI PF13541.6 CBK19616.2 - 2.4e-08 33.9 0.0 5.7e-08 32.6 0.0 1.6 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase LON_substr_bdg PF02190.16 CBK19616.2 - 2.8e-08 33.9 0.1 7.7e-08 32.5 0.0 1.8 2 0 0 2 2 1 1 ATP-dependent protease La (LON) substrate-binding domain AAA_5 PF07728.14 CBK19616.2 - 1.4e-06 28.3 0.0 5.7e-06 26.4 0.0 2.2 2 1 0 2 2 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 CBK19616.2 - 8.3e-06 26.0 0.0 2.1e-05 24.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_23 PF13476.6 CBK19616.2 - 1.6e-05 25.5 2.7 0.001 19.6 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_PrkA PF08298.11 CBK19616.2 - 6.3e-05 22.0 0.0 0.00013 21.0 0.0 1.4 1 0 0 1 1 1 1 PrkA AAA domain AAA_16 PF13191.6 CBK19616.2 - 0.00011 22.6 0.0 0.00046 20.6 0.0 2.1 1 0 0 1 1 1 1 AAA ATPase domain TIP49 PF06068.13 CBK19616.2 - 0.00014 21.2 1.6 0.00019 20.8 0.1 1.9 2 0 0 2 2 2 1 TIP49 P-loop domain RuvB_N PF05496.12 CBK19616.2 - 0.00022 21.0 0.0 0.0008 19.2 0.0 1.9 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_7 PF12775.7 CBK19616.2 - 0.0027 17.2 0.3 0.039 13.5 0.0 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_33 PF13671.6 CBK19616.2 - 0.0047 17.1 0.0 0.014 15.5 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 CBK19616.2 - 0.0054 17.0 3.0 0.17 12.1 0.2 3.6 3 1 0 3 3 2 1 AAA domain NACHT PF05729.12 CBK19616.2 - 0.0098 15.8 0.2 0.093 12.6 0.0 2.7 4 0 0 4 4 4 1 NACHT domain RNA_helicase PF00910.22 CBK19616.2 - 0.01 16.2 0.0 0.03 14.7 0.0 1.8 1 0 0 1 1 1 0 RNA helicase AAA_18 PF13238.6 CBK19616.2 - 0.011 16.3 0.0 0.034 14.7 0.0 1.9 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 CBK19616.2 - 0.017 15.1 0.0 0.054 13.4 0.0 1.8 2 0 0 2 2 1 0 RsgA GTPase IstB_IS21 PF01695.17 CBK19616.2 - 0.018 14.8 0.0 0.047 13.4 0.0 1.7 1 0 0 1 1 1 0 IstB-like ATP binding protein TsaE PF02367.17 CBK19616.2 - 0.022 14.8 0.0 0.053 13.5 0.0 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_19 PF13245.6 CBK19616.2 - 0.023 15.0 0.0 0.34 11.2 0.0 2.7 3 0 0 3 3 3 0 AAA domain AAA_6 PF12774.7 CBK19616.2 - 0.029 13.3 0.1 0.1 11.5 0.1 1.9 2 0 0 2 2 2 0 Hydrolytic ATP binding site of dynein motor region AAA_25 PF13481.6 CBK19616.2 - 0.03 13.9 0.8 0.17 11.4 0.1 2.3 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 CBK19616.2 - 0.031 14.0 0.1 0.082 12.6 0.0 1.7 2 0 0 2 2 1 0 AAA domain Mg_chelatase PF01078.21 CBK19616.2 - 0.035 13.5 0.1 0.14 11.5 0.0 2.0 2 0 0 2 2 1 0 Magnesium chelatase, subunit ChlI DUF815 PF05673.13 CBK19616.2 - 0.043 13.0 0.0 0.38 9.9 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) ABC_tran PF00005.27 CBK19616.2 - 0.045 14.3 0.3 0.15 12.6 0.0 2.0 2 0 0 2 2 2 0 ABC transporter Cytidylate_kin PF02224.18 CBK19616.2 - 0.052 13.3 0.4 0.14 11.9 0.0 1.8 2 0 0 2 2 1 0 Cytidylate kinase Parvo_NS1 PF01057.17 CBK19616.2 - 0.059 12.4 0.0 0.14 11.2 0.0 1.5 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_14 PF13173.6 CBK19616.2 - 0.092 12.8 0.0 0.31 11.1 0.0 2.0 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 CBK19616.2 - 0.13 12.5 0.0 0.39 11.0 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 CBK19616.2 - 0.14 11.9 0.0 0.26 11.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain CCDC158 PF15921.5 CBK19616.2 - 2.2 6.0 7.8 0.59 7.9 5.0 1.3 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 158 DnaJ_C PF01556.18 CBK19617.2 - 1.4e-26 93.4 0.0 2e-26 92.9 0.0 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 CBK19617.2 - 0.00022 21.3 0.1 0.00034 20.7 0.1 1.3 1 0 0 1 1 1 1 DnaJ domain CK_II_beta PF01214.18 CBK19618.2 - 5e-72 241.5 1.4 5.9e-72 241.3 1.4 1.1 1 0 0 1 1 1 1 Casein kinase II regulatory subunit Collagen PF01391.18 CBK19619.2 - 0.00042 20.0 26.4 0.033 14.0 2.4 3.3 3 0 0 3 3 3 3 Collagen triple helix repeat (20 copies) GREB1 PF15782.5 CBK19619.2 - 2.7 5.0 31.9 3.5 4.6 31.9 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer DUF4407 PF14362.6 CBK19619.2 - 9.2 5.5 32.5 19 4.5 32.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Myb_DNA-binding PF00249.31 CBK19620.2 - 1.5e-05 25.1 0.0 6.7e-05 23.0 0.0 2.0 2 0 0 2 2 2 1 Myb-like DNA-binding domain U-box PF04564.15 CBK19620.2 - 0.0039 17.3 0.1 0.0076 16.4 0.1 1.5 1 0 0 1 1 1 1 U-box domain Atrophin-1 PF03154.15 CBK19620.2 - 0.2 9.9 2.4 0.26 9.5 2.4 1.0 1 0 0 1 1 1 0 Atrophin-1 family EB1 PF03271.17 CBK19621.2 - 3.8e-09 36.6 0.4 1.2e-08 35.1 0.4 1.9 1 0 0 1 1 1 1 EB1-like C-terminal motif CH PF00307.31 CBK19621.2 - 6.8e-08 32.7 0.1 2.1e-07 31.1 0.0 1.8 2 0 0 2 2 2 1 Calponin homology (CH) domain CH_2 PF06294.11 CBK19621.2 - 8.8e-07 29.0 0.1 4.4e-06 26.7 0.0 2.1 2 0 0 2 2 2 1 CH-like domain in sperm protein CAMSAP_CH PF11971.8 CBK19621.2 - 0.00068 19.4 0.0 0.0019 18.0 0.0 1.7 1 0 0 1 1 1 1 CAMSAP CH domain Prefoldin_2 PF01920.20 CBK19621.2 - 0.046 13.7 2.7 0.058 13.4 1.6 1.7 1 1 0 1 1 1 0 Prefoldin subunit FlxA PF14282.6 CBK19621.2 - 0.064 13.2 0.5 0.13 12.2 0.5 1.5 1 0 0 1 1 1 0 FlxA-like protein bZIP_1 PF00170.21 CBK19621.2 - 0.14 12.3 1.5 0.28 11.3 1.5 1.5 1 0 0 1 1 1 0 bZIP transcription factor Tropomyosin_1 PF12718.7 CBK19621.2 - 0.45 10.7 6.3 0.73 10.0 6.3 1.2 1 0 0 1 1 1 0 Tropomyosin like HALZ PF02183.18 CBK19621.2 - 0.75 10.1 6.6 13 6.1 1.8 3.2 3 0 0 3 3 3 0 Homeobox associated leucine zipper Rho_Binding PF08912.11 CBK19621.2 - 6.5 7.6 7.0 1.5 9.7 2.5 2.1 2 0 0 2 2 2 0 Rho Binding SWIM PF04434.17 CBK19622.2 - 1.3e-06 28.0 0.1 3.4e-06 26.6 0.1 1.8 1 0 0 1 1 1 1 SWIM zinc finger MULE PF10551.9 CBK19622.2 - 0.018 15.5 0.0 0.059 13.8 0.0 1.9 1 0 0 1 1 1 0 MULE transposase domain PRCC PF10253.9 CBK19622.2 - 0.29 11.9 6.4 0.52 11.1 6.4 1.4 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting Mucin PF01456.17 CBK19622.2 - 0.4 10.7 35.8 0.71 9.9 35.8 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein Med3 PF11593.8 CBK19622.2 - 1.5 7.9 29.5 2.6 7.1 29.5 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal TFIIA PF03153.13 CBK19622.2 - 7.1 6.5 5.4 10 6.0 5.4 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit WD40 PF00400.32 CBK19623.2 - 0.00076 20.2 0.3 6.3 7.8 0.0 4.0 4 0 0 4 4 4 1 WD domain, G-beta repeat Mto2_bdg PF12808.7 CBK19623.2 - 0.01 16.1 2.2 0.014 15.7 0.9 1.8 1 1 1 2 2 2 0 Micro-tubular organiser Mto1 C-term Mto2-binding region RasGAP_C PF03836.15 CBK19623.2 - 0.016 15.4 1.5 0.016 15.4 1.5 1.6 2 0 0 2 2 2 0 RasGAP C-terminus SOGA PF11365.8 CBK19623.2 - 0.05 14.7 4.7 0.23 12.6 4.7 2.1 1 1 0 1 1 1 0 Protein SOGA Jnk-SapK_ap_N PF09744.9 CBK19623.2 - 0.052 13.8 4.7 0.098 12.9 4.7 1.4 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 ApoLp-III PF07464.11 CBK19623.2 - 0.057 13.5 3.3 0.33 11.0 3.8 1.9 1 1 1 2 2 2 0 Apolipophorin-III precursor (apoLp-III) Cnn_1N PF07989.11 CBK19623.2 - 0.057 13.6 5.4 0.06 13.5 2.6 2.3 1 1 1 2 2 2 0 Centrosomin N-terminal motif 1 DUF4510 PF14971.6 CBK19623.2 - 0.087 13.2 0.2 0.15 12.4 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4510) CorA PF01544.18 CBK19623.2 - 0.096 12.0 0.8 0.16 11.3 0.8 1.3 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein MbeD_MobD PF04899.12 CBK19623.2 - 0.11 12.7 0.3 0.11 12.7 0.3 1.8 2 0 0 2 2 1 0 MbeD/MobD like Swi5 PF07061.11 CBK19623.2 - 0.11 12.6 3.2 0.25 11.4 3.2 1.6 1 0 0 1 1 1 0 Swi5 SlyX PF04102.12 CBK19623.2 - 0.15 12.7 2.9 0.37 11.4 2.9 1.6 1 1 0 1 1 1 0 SlyX Csm1_N PF18504.1 CBK19623.2 - 0.22 11.9 7.3 2.7 8.4 6.8 2.5 1 1 1 2 2 2 0 Csm1 N-terminal domain ZapB PF06005.12 CBK19623.2 - 0.28 11.7 9.6 2.7 8.5 0.8 2.3 1 1 1 2 2 2 0 Cell division protein ZapB dCache_2 PF08269.11 CBK19623.2 - 0.42 9.7 4.0 0.52 9.4 0.9 2.4 2 1 1 3 3 3 0 Cache domain bZIP_2 PF07716.15 CBK19623.2 - 0.8 9.8 7.5 1.5 8.9 1.4 2.4 1 1 1 2 2 2 0 Basic region leucine zipper BST2 PF16716.5 CBK19623.2 - 1 10.0 6.1 2.1 9.0 5.1 2.0 1 1 1 2 2 2 0 Bone marrow stromal antigen 2 DivIC PF04977.15 CBK19623.2 - 1.2 9.0 7.3 4.7 7.1 1.9 2.4 1 1 1 2 2 2 0 Septum formation initiator bZIP_1 PF00170.21 CBK19623.2 - 6.4 7.0 10.9 0.32 11.1 0.6 2.5 2 1 1 3 3 2 0 bZIP transcription factor Fer2 PF00111.27 CBK19624.2 - 2.5e-06 27.4 0.1 4.3e-06 26.6 0.1 1.4 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Cytochrome_C7 PF14522.6 CBK19624.2 - 0.0045 17.0 0.5 0.26 11.3 0.1 1.6 1 1 1 2 2 2 2 Cytochrome c7 and related cytochrome c GSu_C4xC__C2xCH PF09698.10 CBK19624.2 - 1.2 10.0 5.9 0.55 11.0 3.0 1.9 2 0 0 2 2 2 0 Geobacter CxxxxCH...CXXCH motif (GSu_C4xC__C2xCH) Transcrip_reg PF01709.20 CBK19625.2 - 2.7e-61 207.1 0.1 3.5e-61 206.7 0.1 1.0 1 0 0 1 1 1 1 Transcriptional regulator Methyltransf_25 PF13649.6 CBK19626.2 - 8.2e-12 45.7 0.0 3e-11 43.9 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain PrmA PF06325.13 CBK19626.2 - 3.1e-11 43.2 0.0 4.5e-11 42.7 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_11 PF08241.12 CBK19626.2 - 1.3e-08 35.3 0.0 4.7e-08 33.6 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 CBK19626.2 - 3.6e-07 30.1 0.0 7.4e-07 29.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 CBK19626.2 - 6.4e-07 29.1 0.0 1e-06 28.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_18 PF12847.7 CBK19626.2 - 3.8e-06 26.9 0.0 6e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 CBK19626.2 - 6e-06 25.8 0.1 8.2e-06 25.3 0.1 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.6 CBK19626.2 - 1.1e-05 25.4 0.0 1.7e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.16 CBK19626.2 - 3.8e-05 23.5 0.1 7.6e-05 22.5 0.1 1.4 1 0 0 1 1 1 1 Met-10+ like-protein PRMT5 PF05185.16 CBK19626.2 - 0.0001 22.2 0.0 0.00015 21.7 0.0 1.2 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase PRMT5_C PF17286.2 CBK19626.2 - 0.00021 21.2 0.0 0.00032 20.6 0.0 1.2 1 0 0 1 1 1 1 PRMT5 oligomerisation domain TehB PF03848.14 CBK19626.2 - 0.0024 17.3 0.0 0.0046 16.4 0.0 1.4 1 0 0 1 1 1 1 Tellurite resistance protein TehB Methyltransf_9 PF08003.11 CBK19626.2 - 0.0026 16.8 0.0 0.0042 16.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_12 PF08242.12 CBK19626.2 - 0.016 15.9 0.0 0.04 14.7 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Cons_hypoth95 PF03602.15 CBK19626.2 - 0.03 14.0 0.0 0.048 13.3 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical protein 95 PCMT PF01135.19 CBK19626.2 - 0.032 14.0 0.1 0.055 13.2 0.1 1.4 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) GidB PF02527.15 CBK19626.2 - 0.039 13.3 0.0 0.062 12.6 0.0 1.3 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G Methyltransf_24 PF13578.6 CBK19626.2 - 0.057 14.4 0.0 0.1 13.6 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Peptidase_C2 PF00648.21 CBK19627.2 - 1.7e-32 112.6 0.0 2.7e-32 112.0 0.0 1.2 1 0 0 1 1 1 1 Calpain family cysteine protease PNTB PF02233.16 CBK19628.2 - 7.8e-170 565.7 14.4 7.8e-170 565.7 14.4 2.2 2 0 0 2 2 2 2 NAD(P) transhydrogenase beta subunit AlaDh_PNT_C PF01262.21 CBK19628.2 - 2.4e-63 213.3 0.8 4.9e-63 212.3 0.8 1.6 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain AlaDh_PNT_N PF05222.15 CBK19628.2 - 1.8e-43 148.1 0.6 6.3e-43 146.3 0.2 2.1 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, N-terminal domain PNTB_4TM PF12769.7 CBK19628.2 - 3.6e-32 110.7 2.8 3.6e-32 110.7 2.8 4.5 4 0 0 4 4 4 1 4TM region of pyridine nucleotide transhydrogenase, mitoch 2-Hacid_dh_C PF02826.19 CBK19628.2 - 0.00035 20.0 0.9 0.41 10.0 0.0 3.4 3 1 0 3 3 3 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Pyr_redox PF00070.27 CBK19628.2 - 0.002 18.6 0.2 0.0074 16.8 0.2 2.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 CBK19628.2 - 0.0052 16.1 0.5 0.014 14.7 0.2 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase TPP_enzyme_M PF00205.22 CBK19628.2 - 0.0058 16.4 0.2 2 8.1 0.1 3.4 2 1 1 3 3 3 1 Thiamine pyrophosphate enzyme, central domain NAD_binding_8 PF13450.6 CBK19628.2 - 0.025 14.8 2.3 0.74 10.1 0.5 3.5 3 0 0 3 3 3 0 NAD(P)-binding Rossmann-like domain Ribosomal_L13 PF00572.18 CBK19629.2 - 1.3e-08 35.2 0.0 3.2e-08 33.9 0.0 1.7 1 1 0 1 1 1 1 Ribosomal protein L13 Rhomboid PF01694.22 CBK19630.2 - 1.7e-08 34.6 16.4 2.4e-08 34.1 16.4 1.2 1 0 0 1 1 1 1 Rhomboid family C_GCAxxG_C_C PF09719.10 CBK19630.2 - 0.15 12.3 0.1 0.23 11.8 0.1 1.3 1 0 0 1 1 1 0 Putative redox-active protein (C_GCAxxG_C_C) ATP_bind_3 PF01171.20 CBK19631.2 - 3.9e-16 59.3 0.0 5.9e-16 58.7 0.0 1.3 1 0 0 1 1 1 1 PP-loop family Spc7 PF08317.11 CBK19632.2 - 0.00033 19.6 43.7 0.00033 19.6 43.7 7.2 2 1 7 9 9 9 3 Spc7 kinetochore protein Golgin_A5 PF09787.9 CBK19632.2 - 0.00046 19.7 28.8 0.00046 19.7 28.8 6.6 2 1 6 8 8 8 2 Golgin subfamily A member 5 WEMBL PF05701.11 CBK19632.2 - 0.0048 15.7 224.1 0.024 13.4 115.7 4.0 2 1 2 4 4 4 3 Weak chloroplast movement under blue light Auto_anti-p27 PF06677.12 CBK19632.2 - 0.074 13.2 1.0 0.14 12.4 1.0 1.4 1 0 0 1 1 1 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) TPR_MLP1_2 PF07926.12 CBK19632.2 - 4 7.5 250.2 0.079 13.0 19.6 11.1 2 1 9 11 11 11 0 TPR/MLP1/MLP2-like protein CAF1 PF04857.20 CBK19633.2 - 9e-59 199.2 0.0 1.4e-58 198.6 0.0 1.3 1 0 0 1 1 1 1 CAF1 family ribonuclease NCBP3 PF10309.9 CBK19633.2 - 0.04 13.8 0.1 0.097 12.5 0.1 1.7 1 0 0 1 1 1 0 Nuclear cap-binding protein subunit 3 Piwi PF02171.17 CBK19634.2 - 3.1e-73 246.7 0.0 4.4e-73 246.2 0.0 1.2 1 0 0 1 1 1 1 Piwi domain PAZ PF02170.22 CBK19634.2 - 4.3e-12 46.0 5.9 5.1e-12 45.8 3.7 2.0 2 0 0 2 2 2 1 PAZ domain ArgoL1 PF08699.10 CBK19634.2 - 5.7e-05 22.7 0.1 0.00017 21.2 0.0 1.8 2 0 0 2 2 2 1 Argonaute linker 1 domain ArgoN PF16486.5 CBK19634.2 - 0.00024 21.7 0.3 0.00069 20.2 0.3 1.8 1 0 0 1 1 1 1 N-terminal domain of argonaute PP2C PF00481.21 CBK19637.2 - 7.2e-17 61.9 0.0 8.6e-17 61.6 0.0 1.0 1 0 0 1 1 1 1 Protein phosphatase 2C Clathrin PF00637.20 CBK19638.2 - 2e-17 63.4 12.0 2.1e-11 43.9 1.5 2.8 2 1 0 2 2 2 2 Region in Clathrin and VPS TPR_2 PF07719.17 CBK19638.2 - 0.17 12.1 2.2 24 5.3 0.1 4.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_11 PF13414.6 CBK19638.2 - 0.33 10.7 1.4 1.4 8.7 0.8 2.4 2 0 0 2 2 2 0 TPR repeat ANAPC3 PF12895.7 CBK19638.2 - 0.82 9.9 7.2 30 4.9 0.1 4.8 4 2 0 5 5 5 0 Anaphase-promoting complex, cyclosome, subunit 3 PPR PF01535.20 CBK19638.2 - 2.2 8.7 4.6 17 5.9 0.1 4.4 5 0 0 5 5 5 0 PPR repeat zf-C3H2C3 PF17122.5 CBK19639.2 - 1.7e-07 31.1 10.0 3e-07 30.4 10.0 1.4 1 0 0 1 1 1 1 Zinc-finger zf-C3HC4_2 PF13923.6 CBK19639.2 - 5.4e-05 22.9 9.1 5.4e-05 22.9 9.1 1.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CBK19639.2 - 8.8e-05 22.4 3.9 0.00021 21.3 3.7 1.8 1 1 0 1 1 1 1 RING-type zinc-finger zf-RING_2 PF13639.6 CBK19639.2 - 0.0019 18.5 7.3 0.0019 18.5 7.3 1.6 2 0 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.6 CBK19639.2 - 0.0062 16.5 7.6 0.013 15.4 7.6 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.7 CBK19639.2 - 0.016 15.4 7.4 0.033 14.5 7.4 1.6 1 0 0 1 1 1 0 RING-H2 zinc finger domain VPS11_C PF12451.8 CBK19639.2 - 0.026 14.8 0.1 0.038 14.2 0.1 1.3 1 0 0 1 1 1 0 Vacuolar protein sorting protein 11 C terminal zf-C3HC4 PF00097.25 CBK19639.2 - 1.6 8.7 11.9 0.057 13.3 5.9 1.8 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_1 PF14446.6 CBK19639.2 - 6.3 6.8 11.7 87 3.2 11.7 2.7 1 1 0 1 1 1 0 Prokaryotic RING finger family 1 RPN1_RPN2_N PF17781.1 CBK19640.2 - 2.1e-28 99.6 0.5 3.5e-28 98.9 0.5 1.3 1 0 0 1 1 1 1 RPN1/RPN2 N-terminal domain PC_rep PF01851.22 CBK19640.2 - 1.4e-05 25.3 4.7 0.47 11.0 0.0 5.9 6 0 0 6 6 6 2 Proteasome/cyclosome repeat HEAT_2 PF13646.6 CBK19640.2 - 3.9e-05 24.0 0.3 0.00018 21.8 0.3 2.2 1 0 0 1 1 1 1 HEAT repeats Arm PF00514.23 CBK19640.2 - 0.36 10.9 3.1 1.3 9.2 0.1 3.2 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat XRN_N PF03159.18 CBK19642.2 - 6.8e-81 271.3 0.0 8.6e-81 270.9 0.0 1.1 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus XRN_M PF17846.1 CBK19642.2 - 6.6e-57 193.4 0.8 1.3e-29 103.4 0.2 2.2 1 1 1 2 2 2 2 Xrn1 helical domain Ribosom_S12_S23 PF00164.25 CBK19643.2 - 4.2e-48 161.7 1.9 5.1e-48 161.4 1.9 1.2 1 0 0 1 1 1 1 Ribosomal protein S12/S23 Ribosomal_L27A PF00828.19 CBK19644.2 - 9.5e-23 81.3 0.0 1.3e-22 80.8 0.0 1.2 1 0 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A Fibrillarin PF01269.17 CBK19645.2 - 8.4e-105 348.9 0.0 1e-104 348.6 0.0 1.0 1 0 0 1 1 1 1 Fibrillarin GCD14 PF08704.10 CBK19645.2 - 6.5e-05 22.7 0.1 0.00012 21.8 0.1 1.4 1 1 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit PCMT PF01135.19 CBK19645.2 - 0.076 12.8 0.0 0.13 12.0 0.0 1.4 1 1 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Pro_isomerase PF00160.21 CBK19647.2 - 2.4e-48 164.4 0.0 4.7e-48 163.4 0.0 1.5 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD WD40 PF00400.32 CBK19647.2 - 6.4e-08 33.1 0.0 0.08 13.8 0.0 3.8 3 0 0 3 3 3 2 WD domain, G-beta repeat SAP PF02037.27 CBK19647.2 - 2.6e-06 27.1 0.0 4.1e-06 26.4 0.0 1.3 1 0 0 1 1 1 1 SAP domain BUD22 PF09073.10 CBK19647.2 - 4 6.7 23.2 5.9 6.1 23.2 1.1 1 0 0 1 1 1 0 BUD22 zf-GRF PF06839.12 CBK19648.2 - 7.5e-17 61.2 3.6 7.5e-17 61.2 3.6 2.7 2 1 0 2 2 2 1 GRF zinc finger zf-CCHC PF00098.23 CBK19648.2 - 3.8e-07 29.9 0.3 8e-07 28.9 0.3 1.6 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.6 CBK19648.2 - 0.013 15.4 2.1 0.025 14.6 2.1 1.5 1 0 0 1 1 1 0 Zinc knuckle Topoisom_bac PF01131.20 CBK19649.2 - 8.9e-69 232.5 0.0 2e-68 231.3 0.0 1.5 2 0 0 2 2 2 1 DNA topoisomerase Toprim PF01751.22 CBK19649.2 - 6.1e-14 52.1 0.0 1.3e-13 51.1 0.0 1.5 1 0 0 1 1 1 1 Toprim domain DZR PF12773.7 CBK19649.2 - 0.0093 16.0 5.1 0.13 12.3 1.2 3.1 1 1 2 3 3 3 2 Double zinc ribbon Zn-ribbon_8 PF09723.10 CBK19649.2 - 0.46 10.6 8.0 10 6.3 0.0 4.1 2 1 1 3 3 3 0 Zinc ribbon domain zf-C4_Topoisom PF01396.19 CBK19649.2 - 3.8 7.4 8.5 15 5.5 0.5 3.2 2 1 0 2 2 2 0 Topoisomerase DNA binding C4 zinc finger OSK PF17182.4 CBK19650.2 - 0.027 13.7 0.2 0.049 12.9 0.2 1.4 1 0 0 1 1 1 0 OSK domain MORN PF02493.20 CBK19651.2 - 7.9e-08 31.8 33.4 0.00029 20.6 0.2 6.8 7 0 0 7 7 7 4 MORN repeat MORN_2 PF07661.13 CBK19651.2 - 1.6e-06 27.7 5.7 1.5 9.3 0.0 7.1 7 0 0 7 7 7 2 MORN repeat variant Nup35_RRM PF05172.13 CBK19651.2 - 0.015 15.2 0.0 0.038 13.9 0.0 1.6 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif DUF5122 PF17164.4 CBK19651.2 - 0.073 13.4 0.1 9.5 6.6 0.0 3.2 2 1 1 3 3 3 0 Domain of unknown function (DUF5122) beta-propeller F-box-like PF12937.7 CBK19652.2 - 0.00024 20.9 0.1 0.0005 19.9 0.1 1.6 1 0 0 1 1 1 1 F-box-like BCDHK_Adom3 PF10436.9 CBK19653.2 - 1.2e-15 57.7 0.1 2.2e-15 56.9 0.1 1.3 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 CBK19653.2 - 1.8e-11 44.5 0.0 4.6e-06 27.1 0.0 2.3 2 0 0 2 2 2 2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 CBK19653.2 - 0.00037 20.3 0.0 0.0007 19.4 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DnaB_2 PF07261.11 CBK19653.2 - 0.11 12.3 0.0 0.28 11.0 0.0 1.8 1 0 0 1 1 1 0 Replication initiation and membrane attachment SNF2_N PF00176.23 CBK19654.2 - 9.4e-57 192.3 1.6 1.9e-56 191.3 0.5 1.8 1 1 1 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 CBK19654.2 - 1.4e-20 73.7 0.0 3.7e-20 72.3 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain FYRN PF05964.14 CBK19654.2 - 1.3e-13 50.6 0.4 2.4e-13 49.7 0.4 1.5 1 0 0 1 1 1 1 F/Y-rich N-terminus ResIII PF04851.15 CBK19654.2 - 4e-08 33.4 0.0 1.2e-07 31.9 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Myb_DNA-binding PF00249.31 CBK19654.2 - 0.0009 19.4 5.4 1.3 9.3 1.2 4.4 4 0 0 4 4 4 2 Myb-like DNA-binding domain DEAD PF00270.29 CBK19654.2 - 0.0015 18.4 0.0 0.003 17.4 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase SWI2_SNF2 PF18766.1 CBK19654.2 - 0.0071 16.0 0.0 0.022 14.4 0.0 1.8 1 0 0 1 1 1 1 SWI2/SNF2 ATPase HDA2-3 PF11496.8 CBK19654.2 - 0.028 13.6 0.2 0.16 11.1 0.2 2.2 1 1 0 1 1 1 0 Class II histone deacetylase complex subunits 2 and 3 RNA_pol_Rpb5_C PF01191.19 CBK19655.2 - 8.7e-33 112.0 0.2 1.7e-32 111.1 0.2 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb5, C-terminal domain RNA_pol_Rpb5_N PF03871.14 CBK19655.2 - 1.9e-18 66.8 2.3 2.8e-18 66.2 0.7 2.0 1 1 1 2 2 2 1 RNA polymerase Rpb5, N-terminal domain Pyr_excise PF03013.14 CBK19655.2 - 0.078 13.0 0.0 0.17 11.9 0.0 1.6 1 0 0 1 1 1 0 Pyrimidine dimer DNA glycosylase Pkinase PF00069.25 CBK19656.2 - 1.6e-43 149.0 0.4 2e-42 145.4 0.4 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBK19656.2 - 4.1e-27 95.1 0.0 5.2e-27 94.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 CBK19656.2 - 8.8e-09 34.8 0.1 1.1e-08 34.4 0.1 1.1 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 CBK19656.2 - 1.1e-05 24.8 0.1 1.6e-05 24.4 0.1 1.1 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CBK19656.2 - 0.00019 21.5 0.0 0.00029 20.8 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 CBK19656.2 - 0.0024 16.7 0.1 0.0044 15.9 0.0 1.4 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 CBK19656.2 - 0.0037 16.6 0.0 0.008 15.5 0.0 1.5 1 1 0 1 1 1 1 Kinase-like Choline_kinase PF01633.20 CBK19656.2 - 0.09 12.3 0.3 0.13 11.9 0.3 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase YukC PF10140.9 CBK19656.2 - 0.091 11.6 0.0 0.17 10.7 0.0 1.4 1 1 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukC DUF2462 PF09495.10 CBK19657.2 - 4.2e-12 46.6 16.9 4.2e-12 46.6 16.9 2.0 1 1 1 2 2 2 1 Protein of unknown function (DUF2462) RPOL_N PF14700.6 CBK19657.2 - 5.5 6.3 15.8 0.11 11.9 7.7 1.8 1 1 1 2 2 2 0 DNA-directed RNA polymerase N-terminal AAA_lid_9 PF17871.1 CBK19657.2 - 7.8 6.5 13.4 0.1 12.5 3.1 2.2 2 1 0 2 2 2 0 AAA lid domain DEAD PF00270.29 CBK19658.2 - 5.9e-48 162.9 0.3 4.2e-46 156.9 0.0 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CBK19658.2 - 4e-31 107.6 0.3 2.3e-30 105.2 0.1 2.4 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 CBK19658.2 - 1.8e-05 24.8 0.0 5.3e-05 23.3 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit UTP25 PF06862.12 CBK19658.2 - 0.0014 17.5 0.0 0.075 11.8 0.0 2.2 2 0 0 2 2 2 2 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 TFIIB PF00382.19 CBK19658.2 - 0.042 13.9 0.0 0.13 12.4 0.0 1.8 1 0 0 1 1 1 0 Transcription factor TFIIB repeat PX PF00787.24 CBK19659.2 - 0.016 15.1 0.6 0.046 13.7 0.0 2.0 2 0 0 2 2 2 0 PX domain TFIIE-A_C PF11521.8 CBK19659.2 - 0.028 14.7 4.1 0.082 13.2 4.1 1.7 1 0 0 1 1 1 0 C-terminal general transcription factor TFIIE alpha Tma16 PF11176.8 CBK19659.2 - 0.25 11.2 4.0 3.6 7.4 0.1 3.2 3 0 0 3 3 3 0 Translation machinery-associated protein 16 RseA_N PF03872.13 CBK19660.2 - 0.11 13.0 0.1 0.18 12.3 0.1 1.2 1 0 0 1 1 1 0 Anti sigma-E protein RseA, N-terminal domain UPF0542 PF15086.6 CBK19660.2 - 0.12 12.3 1.7 0.64 10.0 0.2 2.3 2 0 0 2 2 2 0 Uncharacterised protein family UPF0542 DUF1460 PF07313.12 CBK19660.2 - 0.19 11.1 0.0 0.75 9.1 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1460) SieB PF14163.6 CBK19660.2 - 3.6 7.1 5.1 2.5 7.6 0.1 2.4 2 0 0 2 2 2 0 Super-infection exclusion protein B Pro_isomerase PF00160.21 CBK19662.2 - 1.4e-13 51.4 0.0 1.6e-13 51.3 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Acetate_kinase PF00871.17 CBK19663.2 - 0.028 13.1 0.1 0.032 12.9 0.1 1.1 1 0 0 1 1 1 0 Acetokinase family SUKH_5 PF14567.6 CBK19663.2 - 0.051 13.3 0.2 0.072 12.8 0.2 1.2 1 1 0 1 1 1 0 SMI1-KNR4 cell-wall Vps52 PF04129.12 CBK19664.2 - 2.9e-14 52.7 2.2 3.6e-14 52.4 2.2 1.0 1 0 0 1 1 1 1 Vps52 / Sac2 family DDRGK PF09756.9 CBK19665.2 - 1.5e-34 119.3 29.7 1.5e-34 119.3 29.7 2.0 2 0 0 2 2 2 1 DDRGK domain AHD PF17793.1 CBK19665.2 - 0.01 15.6 0.4 1.7 8.5 0.1 2.6 2 0 0 2 2 2 0 ANC1 homology domain (AHD) HTH_DeoR PF08220.12 CBK19665.2 - 0.019 14.7 0.3 0.81 9.5 0.0 2.7 3 0 0 3 3 3 0 DeoR-like helix-turn-helix domain HTH_24 PF13412.6 CBK19665.2 - 0.019 14.5 0.3 1.2 8.7 0.0 2.7 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding DUF3107 PF11305.8 CBK19665.2 - 0.19 12.0 2.4 0.19 12.0 0.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3107) DUF3987 PF13148.6 CBK19665.2 - 2 7.3 15.8 4.3 6.2 15.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) RPN7 PF10602.9 CBK19666.2 - 4.7e-34 117.6 4.3 8.9e-34 116.7 4.3 1.5 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.27 CBK19666.2 - 8.3e-12 45.5 0.4 3.6e-11 43.5 0.0 2.3 2 1 0 2 2 2 1 PCI domain TPR_2 PF07719.17 CBK19666.2 - 0.00022 21.1 0.2 0.036 14.2 0.1 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.6 CBK19666.2 - 0.0016 18.3 0.0 0.016 15.2 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.28 CBK19666.2 - 0.0023 17.7 0.6 0.045 13.6 0.3 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 CBK19666.2 - 0.026 14.8 0.0 0.054 13.8 0.0 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_6 PF13174.6 CBK19666.2 - 0.027 15.1 0.2 0.22 12.2 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.6 CBK19666.2 - 0.029 14.6 0.5 0.095 13.0 0.5 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat Ribosomal_L4 PF00573.22 CBK19667.2 - 2.3e-32 112.2 0.6 2.7e-32 112.0 0.6 1.1 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family MMS1_N PF10433.9 CBK19668.2 - 1.1e-118 397.0 0.0 1.6e-118 396.5 0.0 1.3 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.15 CBK19668.2 - 1.1e-84 284.6 0.0 1.6e-83 280.7 0.0 2.2 2 0 0 2 2 2 1 CPSF A subunit region MCM PF00493.23 CBK19669.2 - 9.5e-97 322.5 0.0 1.5e-96 321.8 0.0 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_lid PF17855.1 CBK19669.2 - 1.2e-24 86.5 0.1 2.4e-24 85.6 0.1 1.5 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_OB PF17207.3 CBK19669.2 - 7.4e-21 74.3 0.3 1.6e-20 73.2 0.3 1.5 1 0 0 1 1 1 1 MCM OB domain Mg_chelatase PF01078.21 CBK19669.2 - 6.6e-06 25.6 0.0 6.7e-05 22.4 0.0 2.2 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 CBK19669.2 - 0.00032 20.6 0.0 0.0019 18.1 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 CBK19669.2 - 0.0022 18.0 0.0 0.0044 17.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.26 CBK19669.2 - 0.094 12.4 0.0 0.29 10.8 0.0 1.7 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_2 PF07724.14 CBK19669.2 - 0.13 12.4 0.0 0.26 11.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) DEAD PF00270.29 CBK19670.2 - 1.8e-48 164.7 0.0 3.4e-48 163.7 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CBK19670.2 - 2.1e-26 92.4 0.0 6.6e-25 87.6 0.0 2.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 CBK19670.2 - 4.5e-05 23.5 0.0 0.00014 21.9 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit SecA_DEAD PF07517.14 CBK19670.2 - 0.0038 16.5 0.0 0.024 13.9 0.0 2.3 1 1 0 1 1 1 1 SecA DEAD-like domain COE1_DBD PF16422.5 CBK19671.2 - 0.14 11.6 0.0 0.2 11.0 0.0 1.2 1 0 0 1 1 1 0 Transcription factor COE1 DNA-binding domain AAA PF00004.29 CBK19672.2 - 0.00016 22.1 0.1 0.00073 20.0 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Glyco_tranf_2_3 PF13641.6 CBK19673.2 - 0.17 11.8 0.0 0.21 11.5 0.0 1.2 1 0 0 1 1 1 0 Glycosyltransferase like family 2 PEX11 PF05648.14 CBK19674.2 - 0.021 14.3 0.2 0.033 13.6 0.2 1.4 1 0 0 1 1 1 0 Peroxisomal biogenesis factor 11 (PEX11) He_PIG PF05345.12 CBK19675.2 - 9.9e-10 38.5 16.3 0.0006 19.9 1.0 4.0 3 0 0 3 3 3 3 Putative Ig domain Phage_lysozyme PF00959.19 CBK19676.2 - 0.022 15.2 0.8 0.036 14.5 0.8 1.5 1 1 0 1 1 1 0 Phage lysozyme Bac_rhamnosid6H PF17389.2 CBK19676.2 - 0.095 11.9 3.2 0.086 12.1 2.3 1.4 1 1 1 2 2 2 0 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain DUF812 PF05667.11 CBK19676.2 - 0.2 10.5 24.5 0.25 10.2 24.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) MAD PF05557.13 CBK19676.2 - 0.36 9.2 26.2 0.63 8.3 26.2 1.3 1 1 0 1 1 1 0 Mitotic checkpoint protein TMF_TATA_bd PF12325.8 CBK19676.2 - 2.8 8.2 26.9 0.96 9.7 14.7 3.0 1 1 2 3 3 3 0 TATA element modulatory factor 1 TATA binding DivIC PF04977.15 CBK19676.2 - 3 7.7 22.4 1.2 9.0 5.5 3.4 2 1 1 3 3 3 0 Septum formation initiator UPF0242 PF06785.11 CBK19676.2 - 6.7 6.8 25.5 7.9 6.5 18.1 2.1 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus CENP-F_leu_zip PF10473.9 CBK19676.2 - 8 6.5 29.1 12 5.9 7.2 2.9 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 KLRAQ PF10205.9 CBK19676.2 - 8.3 6.7 22.4 4.7 7.5 10.6 2.6 1 1 2 3 3 3 0 Predicted coiled-coil domain-containing protein HIP1_clath_bdg PF16515.5 CBK19676.2 - 8.5 7.1 28.2 1.5 9.5 17.2 2.6 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Fez1 PF06818.15 CBK19676.2 - 9.6 6.6 25.9 1.7e+02 2.6 0.6 2.0 1 1 1 2 2 2 0 Fez1 Kinesin PF00225.23 CBK19677.2 - 3e-97 325.5 0.0 6.4e-97 324.5 0.0 1.4 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 CBK19677.2 - 2.3e-25 89.3 0.0 1.3e-24 86.8 0.0 2.0 2 0 0 2 2 2 1 Microtubule binding Helo_like_N PF17111.5 CBK19677.2 - 0.017 14.5 2.7 0.036 13.4 1.6 2.0 2 1 1 3 3 3 0 Fungal N-terminal domain of STAND proteins ATG16 PF08614.11 CBK19677.2 - 0.044 14.0 1.8 0.089 13.0 0.8 1.9 2 1 0 2 2 2 0 Autophagy protein 16 (ATG16) Ribosomal_L29 PF00831.23 CBK19677.2 - 0.048 13.6 0.3 0.52 10.3 0.1 2.5 1 1 1 2 2 2 0 Ribosomal L29 protein DUF1192 PF06698.11 CBK19677.2 - 0.056 13.5 3.0 0.13 12.3 0.1 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1192) BST2 PF16716.5 CBK19677.2 - 0.075 13.6 0.8 13 6.5 0.1 2.8 2 1 0 2 2 2 0 Bone marrow stromal antigen 2 CREPT PF16566.5 CBK19677.2 - 0.2 11.8 0.6 0.36 11.0 0.6 1.3 1 0 0 1 1 1 0 Cell-cycle alteration and expression-elevated protein in tumour Lzipper-MIP1 PF14389.6 CBK19677.2 - 0.65 10.3 3.2 2.4 8.5 2.9 2.2 1 1 1 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 ZapB PF06005.12 CBK19677.2 - 1 9.9 3.4 16 6.0 3.4 2.7 1 1 0 1 1 1 0 Cell division protein ZapB ETF_alpha PF00766.19 CBK19678.2 - 4.2e-14 52.3 0.5 6.5e-14 51.7 0.5 1.3 1 0 0 1 1 1 1 Electron transfer flavoprotein FAD-binding domain Kinesin PF00225.23 CBK19679.2 - 1.2e-32 113.2 0.0 1.2e-32 113.2 0.0 3.4 4 1 0 4 4 4 1 Kinesin motor domain Microtub_bd PF16796.5 CBK19679.2 - 1.4e-28 99.7 0.0 1.4e-28 99.7 0.0 2.5 3 0 0 3 3 3 1 Microtubule binding Dsh_C PF12316.8 CBK19679.2 - 0.5 10.8 7.4 1.4 9.3 7.4 1.8 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal Mto2_bdg PF12808.7 CBK19679.2 - 2.6 8.4 64.3 0.18 12.1 4.6 7.6 5 1 1 6 6 6 0 Micro-tubular organiser Mto1 C-term Mto2-binding region Kinesin PF00225.23 CBK19680.2 - 6e-36 124.0 0.6 6.6e-36 123.9 0.6 1.0 1 0 0 1 1 1 1 Kinesin motor domain Thioredoxin_6 PF13848.6 CBK19681.2 - 4.7e-18 65.7 0.0 2.3e-13 50.4 0.0 2.1 2 0 0 2 2 2 2 Thioredoxin-like domain Thioredoxin PF00085.20 CBK19681.2 - 1.8e-17 63.2 0.0 1.1e-16 60.7 0.1 2.0 2 0 0 2 2 2 1 Thioredoxin OST3_OST6 PF04756.13 CBK19681.2 - 7.4e-07 28.8 0.1 1.2e-06 28.1 0.1 1.3 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family TraF PF13728.6 CBK19681.2 - 0.00015 21.7 0.0 0.00025 20.9 0.0 1.3 1 0 0 1 1 1 1 F plasmid transfer operon protein Thioredoxin_2 PF13098.6 CBK19681.2 - 0.00053 20.4 0.3 0.023 15.2 0.2 3.2 3 1 0 3 3 3 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 CBK19681.2 - 0.0037 17.5 0.1 0.29 11.5 0.1 2.8 1 1 1 2 2 2 1 Thioredoxin-like Thioredoxin_7 PF13899.6 CBK19681.2 - 0.046 13.9 0.0 0.34 11.1 0.0 2.3 2 0 0 2 2 2 0 Thioredoxin-like Thioredoxin_4 PF13462.6 CBK19681.2 - 0.051 13.7 0.4 0.13 12.4 0.3 1.6 1 1 0 1 1 1 0 Thioredoxin ERp29_N PF07912.13 CBK19681.2 - 0.072 13.2 0.2 0.51 10.5 0.2 2.4 2 1 0 2 2 2 0 ERp29, N-terminal domain Thioredoxin_3 PF13192.6 CBK19681.2 - 0.14 12.2 0.0 0.31 11.1 0.0 1.6 1 0 0 1 1 1 0 Thioredoxin domain S4 PF01479.25 CBK19682.2 - 1.8e-12 46.8 0.4 1.8e-12 46.8 0.4 2.2 2 0 0 2 2 2 1 S4 domain zf-DBF PF07535.12 CBK19682.2 - 0.11 12.6 0.0 0.26 11.4 0.0 1.6 1 0 0 1 1 1 0 DBF zinc finger CoA_binding PF02629.19 CBK19683.2 - 7.8e-30 103.4 1.3 7.8e-30 103.4 1.3 2.5 3 0 0 3 3 3 1 CoA binding domain Ligase_CoA PF00549.19 CBK19683.2 - 2.3e-23 82.7 0.1 4.6e-23 81.7 0.1 1.5 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.6 CBK19683.2 - 7.1e-10 38.8 0.0 1.5e-09 37.8 0.0 1.5 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.6 CBK19683.2 - 0.00011 22.6 0.0 0.00024 21.6 0.0 1.6 1 0 0 1 1 1 1 CoA binding domain GFO_IDH_MocA PF01408.22 CBK19683.2 - 0.031 15.1 0.1 0.085 13.7 0.1 1.7 2 0 0 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold SseB PF07179.12 CBK19683.2 - 0.16 12.2 0.0 0.25 11.6 0.0 1.3 1 0 0 1 1 1 0 SseB protein N-terminal domain RRM_1 PF00076.22 CBK19684.2 - 1.1e-33 114.8 0.0 2.7e-16 59.1 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 CBK19684.2 - 0.063 13.3 0.1 0.56 10.3 0.0 2.3 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif CDC27 PF09507.10 CBK19684.2 - 0.12 11.8 56.6 0.15 11.4 56.6 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Asp-B-Hydro_N PF05279.11 CBK19684.2 - 6.7 6.7 53.6 9.9 6.2 53.6 1.3 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Ribosomal_L21e PF01157.18 CBK19685.2 - 3.2e-43 145.7 4.7 5.5e-43 144.9 4.7 1.4 1 0 0 1 1 1 1 Ribosomal protein L21e DUF5506 PF17611.2 CBK19685.2 - 0.0093 15.9 0.3 0.016 15.1 0.3 1.4 1 1 0 1 1 1 1 Family of unknown function (DUF5506) Put_Phosphatase PF06888.12 CBK19685.2 - 0.066 12.6 0.0 0.085 12.2 0.0 1.1 1 0 0 1 1 1 0 Putative Phosphatase Response_reg PF00072.24 CBK19685.2 - 0.14 12.3 0.0 0.27 11.4 0.0 1.4 1 0 0 1 1 1 0 Response regulator receiver domain MSP1b PF03429.13 CBK19685.2 - 0.18 9.9 0.0 0.2 9.7 0.0 1.1 1 0 0 1 1 1 0 Major surface protein 1B TNFR_16_TM PF18422.1 CBK19685.2 - 0.42 10.6 3.5 0.81 9.7 3.5 1.4 1 0 0 1 1 1 0 Tumor necrosis factor receptor member 16 trans-membrane domain MFS_1 PF07690.16 CBK19688.2 - 8.9e-35 120.2 21.1 1.3e-34 119.7 21.1 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 CBK19688.2 - 4.9e-10 38.9 15.4 6.9e-10 38.4 15.4 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_3 PF05977.13 CBK19688.2 - 0.0025 16.3 2.8 0.0046 15.4 2.8 1.3 1 0 0 1 1 1 1 Transmembrane secretion effector Holin_9 PF16936.5 CBK19688.2 - 1.2 9.3 4.9 0.27 11.4 0.4 2.2 2 0 0 2 2 2 0 Putative holin Thioredoxin PF00085.20 CBK19690.2 - 1.3e-37 127.9 0.0 4.2e-19 68.5 0.0 3.9 4 0 0 4 4 4 3 Thioredoxin Thioredoxin_6 PF13848.6 CBK19690.2 - 9.7e-30 103.8 0.0 1.5e-20 73.8 0.0 3.2 3 0 0 3 3 3 3 Thioredoxin-like domain OST3_OST6 PF04756.13 CBK19690.2 - 4.2e-11 42.8 0.0 4.3e-06 26.3 0.0 2.8 3 1 1 4 4 4 2 OST3 / OST6 family, transporter family ERp29_N PF07912.13 CBK19690.2 - 7.1e-05 23.0 0.3 0.018 15.2 0.0 3.7 4 1 0 4 4 4 1 ERp29, N-terminal domain Thioredoxin_2 PF13098.6 CBK19690.2 - 0.00055 20.4 0.1 0.37 11.3 0.1 3.4 3 0 0 3 3 3 1 Thioredoxin-like domain Thioredoxin_7 PF13899.6 CBK19690.2 - 0.0016 18.6 0.1 0.016 15.4 0.1 2.4 2 0 0 2 2 2 1 Thioredoxin-like Thioredoxin_3 PF13192.6 CBK19690.2 - 0.0048 16.9 0.0 0.36 10.9 0.0 2.8 3 0 0 3 3 3 1 Thioredoxin domain Thioredoxin_8 PF13905.6 CBK19690.2 - 0.0071 16.6 0.0 0.42 11.0 0.0 2.8 2 0 0 2 2 2 1 Thioredoxin-like Glutaredoxin PF00462.24 CBK19690.2 - 0.05 13.8 1.0 18 5.6 0.0 3.0 2 1 0 2 2 2 0 Glutaredoxin PAP2 PF01569.21 CBK19691.2 - 1e-23 83.6 0.4 1.5e-23 83.0 0.4 1.2 1 0 0 1 1 1 1 PAP2 superfamily YqfD PF06898.11 CBK19691.2 - 0.12 11.2 0.0 0.18 10.6 0.0 1.2 1 0 0 1 1 1 0 Putative stage IV sporulation protein YqfD ATP-synt_I PF03899.15 CBK19691.2 - 0.13 12.6 2.3 4.7 7.7 0.1 2.5 2 1 1 3 3 3 0 ATP synthase I chain CTD_bind PF04818.13 CBK19692.2 - 3.1e-11 43.9 1.0 7.9e-11 42.6 0.1 2.1 2 1 0 2 2 2 1 RNA polymerase II-binding domain. DUF1286 PF06939.11 CBK19692.2 - 0.058 13.7 0.4 0.13 12.5 0.2 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1286) GCN5L1 PF06320.13 CBK19692.2 - 0.13 12.4 0.2 0.21 11.7 0.2 1.2 1 0 0 1 1 1 0 GCN5-like protein 1 (GCN5L1) IPK PF03770.16 CBK19693.2 - 2.4e-34 119.0 0.1 4e-34 118.2 0.1 1.4 1 1 0 1 1 1 1 Inositol polyphosphate kinase Transket_pyr PF02779.24 CBK19693.2 - 0.011 15.4 0.0 0.014 15.1 0.0 1.1 1 0 0 1 1 1 0 Transketolase, pyrimidine binding domain DUF2634 PF10934.8 CBK19693.2 - 0.013 15.6 0.2 0.018 15.1 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2634) WD40 PF00400.32 CBK19694.2 - 5.1e-29 99.9 5.1 2.7e-07 31.2 0.5 5.4 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBK19694.2 - 3e-12 46.7 0.0 0.024 14.9 0.0 5.2 2 1 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 CBK19694.2 - 5.7e-05 22.0 0.3 0.00094 17.9 0.1 2.5 1 1 2 4 4 4 1 Nucleoporin Nup120/160 CUT PF02376.15 CBK19694.2 - 0.016 15.3 0.1 0.032 14.4 0.1 1.5 1 0 0 1 1 1 0 CUT domain PALB2_WD40 PF16756.5 CBK19694.2 - 0.024 13.6 0.0 0.82 8.5 0.0 2.3 2 0 0 2 2 2 0 Partner and localizer of BRCA2 WD40 domain Ge1_WD40 PF16529.5 CBK19694.2 - 0.063 12.2 0.2 1.8 7.4 0.0 2.5 2 1 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein IL10 PF00726.17 CBK19696.2 - 0.0011 18.5 0.0 0.026 14.0 0.0 2.4 2 0 0 2 2 2 2 Interleukin 10 DCB PF16213.5 CBK19697.2 - 7.1e-16 58.4 1.0 1.3e-15 57.5 1.0 1.4 1 0 0 1 1 1 1 Dimerisation and cyclophilin-binding domain of Mon2 Sec7_N PF12783.7 CBK19697.2 - 0.017 15.0 1.1 0.91 9.4 0.1 2.3 2 0 0 2 2 2 0 Guanine nucleotide exchange factor in Golgi transport N-terminal SET PF00856.28 CBK19699.2 - 6.5e-18 65.7 0.4 8.9e-18 65.2 0.4 1.3 1 0 0 1 1 1 1 SET domain DnaJ PF00226.31 CBK19700.2 - 2.9e-26 91.4 0.8 1.5e-25 89.0 0.2 2.2 2 0 0 2 2 2 1 DnaJ domain TPR_1 PF00515.28 CBK19700.2 - 1.5e-06 27.8 1.6 2.5e-06 27.0 0.2 2.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 CBK19700.2 - 5.1e-05 23.8 0.5 0.00029 21.4 0.1 2.3 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 CBK19700.2 - 6.1e-05 22.8 0.5 0.00032 20.6 0.3 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 CBK19700.2 - 0.00013 21.9 2.2 0.00014 21.8 0.2 2.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 CBK19700.2 - 0.00026 21.6 0.3 0.003 18.2 0.0 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 CBK19700.2 - 0.0003 20.8 0.1 0.00067 19.7 0.1 1.5 1 0 0 1 1 1 1 Fis1 C-terminal tetratricopeptide repeat TPR_19 PF14559.6 CBK19700.2 - 0.00059 20.3 0.1 0.0016 18.9 0.0 1.8 2 0 0 2 2 1 1 Tetratricopeptide repeat Coatomer_E PF04733.14 CBK19700.2 - 0.00064 19.2 0.5 0.00082 18.9 0.5 1.2 1 0 0 1 1 1 1 Coatomer epsilon subunit TPR_12 PF13424.6 CBK19700.2 - 0.0027 17.9 0.1 0.026 14.8 0.0 2.1 2 0 0 2 2 2 1 Tetratricopeptide repeat RLL PF10036.9 CBK19700.2 - 0.0034 17.3 1.5 0.0043 16.9 1.5 1.1 1 0 0 1 1 1 1 RNA transcription, translation and transport factor protein TPR_7 PF13176.6 CBK19700.2 - 0.0049 16.8 0.0 0.022 14.8 0.0 2.1 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_11 PF13414.6 CBK19700.2 - 0.02 14.6 0.1 0.15 11.8 0.0 2.4 2 1 1 3 3 3 0 TPR repeat Ribonuc_P_40 PF08584.11 CBK19700.2 - 0.037 13.3 0.1 0.1 11.9 0.0 1.6 1 1 0 2 2 2 0 Ribonuclease P 40kDa (Rpp40) subunit YfdX PF10938.8 CBK19700.2 - 0.047 13.6 0.6 0.18 11.7 0.0 2.0 2 0 0 2 2 2 0 YfdX protein TPR_10 PF13374.6 CBK19700.2 - 0.073 13.0 0.1 0.15 12.0 0.1 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_6 PF13174.6 CBK19700.2 - 0.09 13.5 1.8 0.3 11.8 0.2 2.5 2 1 1 3 3 3 0 Tetratricopeptide repeat DUF1771 PF08590.10 CBK19700.2 - 0.65 10.4 0.1 0.65 10.4 0.1 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF1771) Rhodanese PF00581.20 CBK19701.2 - 0.024 15.1 0.0 0.048 14.2 0.0 1.5 1 1 0 1 1 1 0 Rhodanese-like domain Ribosomal_S8e PF01201.22 CBK19702.2 - 3.4e-35 121.2 0.1 4.4e-35 120.8 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein S8e Dynamin_M PF01031.20 CBK19703.2 - 2e-68 230.7 0.2 3e-68 230.1 0.2 1.3 1 0 0 1 1 1 1 Dynamin central region Dynamin_N PF00350.23 CBK19703.2 - 1.8e-52 177.8 0.0 4.3e-52 176.6 0.0 1.7 1 0 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.23 CBK19703.2 - 0.00048 20.2 0.1 0.003 17.6 0.1 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 CBK19703.2 - 0.083 12.4 0.2 6.3 6.3 0.1 2.3 2 0 0 2 2 2 0 Ferrous iron transport protein B DUF4203 PF13886.6 CBK19704.2 - 3.6e-36 124.7 29.8 4.1e-36 124.5 29.8 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4203) MadM PF03818.13 CBK19704.2 - 0.12 12.3 0.7 0.12 12.3 0.7 3.5 4 1 1 5 5 5 0 Malonate/sodium symporter MadM subunit DUF308 PF03729.13 CBK19704.2 - 8.5 6.8 29.6 0.067 13.5 5.3 3.4 3 1 0 3 3 3 0 Short repeat of unknown function (DUF308) FANCI_S4 PF14678.6 CBK19705.2 - 6.2e-32 110.7 1.1 9.9e-32 110.0 1.1 1.3 1 0 0 1 1 1 1 FANCI solenoid 4 C6_DPF PF10170.9 CBK19705.2 - 0.022 15.1 0.1 0.043 14.2 0.1 1.5 1 0 0 1 1 1 0 Cysteine-rich domain Myb_DNA-binding PF00249.31 CBK19706.2 - 3.4e-37 126.4 19.2 8.3e-14 51.5 1.0 3.6 3 1 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 CBK19706.2 - 4.9e-33 113.2 14.9 2.1e-13 50.3 0.2 3.2 1 1 2 3 3 3 3 Myb-like DNA-binding domain SLIDE PF09111.10 CBK19706.2 - 0.00035 20.6 0.1 0.36 10.9 0.0 3.1 1 1 2 3 3 3 1 SLIDE MADF_DNA_bdg PF10545.9 CBK19706.2 - 0.0024 18.2 12.1 0.15 12.4 0.1 4.0 2 2 1 4 4 4 2 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_7 PF15963.5 CBK19706.2 - 0.0056 16.5 0.3 0.2 11.6 0.0 2.5 3 0 0 3 3 3 1 Myb DNA-binding like SANT_DAMP1_like PF16282.5 CBK19706.2 - 0.021 15.0 1.6 0.34 11.1 0.0 2.8 2 1 1 3 3 3 0 SANT/Myb-like domain of DAMP1 Collagen PF01391.18 CBK19706.2 - 0.087 12.6 2.8 0.17 11.6 2.8 1.4 1 0 0 1 1 1 0 Collagen triple helix repeat (20 copies) Rap1_C PF11626.8 CBK19706.2 - 0.27 11.3 5.5 1.2 9.2 1.0 3.0 1 1 1 2 2 2 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain Myb_DNA-bind_4 PF13837.6 CBK19706.2 - 0.7 10.3 11.3 7.8 7.0 0.6 3.8 3 2 0 3 3 3 0 Myb/SANT-like DNA-binding domain V-SNARE_C PF12352.8 CBK19707.2 - 2.6e-07 30.8 0.6 2.6e-07 30.8 0.6 3.0 3 0 0 3 3 3 1 Snare region anchored in the vesicle membrane C-terminus V-SNARE PF05008.15 CBK19707.2 - 3.5e-07 30.5 2.1 3.5e-07 30.5 2.1 2.6 2 1 1 3 3 3 1 Vesicle transport v-SNARE protein N-terminus DUF745 PF05335.13 CBK19707.2 - 0.0016 18.2 13.7 0.23 11.1 1.2 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF745) Sec20 PF03908.13 CBK19707.2 - 0.012 15.5 6.0 0.018 14.9 0.2 3.2 1 1 1 3 3 3 0 Sec20 DUF5089 PF17002.5 CBK19707.2 - 0.035 14.0 14.2 0.29 11.0 0.4 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF5089) DUF1192 PF06698.11 CBK19707.2 - 0.046 13.8 0.3 0.098 12.7 0.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1192) Bcr-Abl_Oligo PF09036.10 CBK19707.2 - 0.15 12.1 0.4 0.43 10.6 0.1 1.9 2 0 0 2 2 2 0 Bcr-Abl oncoprotein oligomerisation domain XhlA PF10779.9 CBK19707.2 - 0.19 12.0 12.7 0.18 12.1 1.3 4.0 3 1 1 4 4 4 0 Haemolysin XhlA Spectrin PF00435.21 CBK19707.2 - 0.19 12.2 2.9 0.2 12.2 1.0 2.0 1 1 0 1 1 1 0 Spectrin repeat Syntaxin-6_N PF09177.11 CBK19707.2 - 0.33 11.5 4.3 0.68 10.5 3.0 2.2 1 1 1 2 2 2 0 Syntaxin 6, N-terminal KxDL PF10241.9 CBK19707.2 - 0.36 11.1 13.0 4.8 7.5 0.7 4.2 3 1 2 5 5 5 0 Uncharacterized conserved protein CHDCT2 PF08074.11 CBK19707.2 - 0.62 10.2 5.9 0.26 11.5 1.1 2.1 1 1 1 2 2 2 0 CHDCT2 (NUC038) domain SNARE PF05739.19 CBK19707.2 - 1 9.4 9.2 0.31 11.1 3.7 2.6 2 0 0 2 2 2 0 SNARE domain Potass_KdpF PF09604.10 CBK19707.2 - 1.1 9.3 4.6 2.1 8.4 4.6 1.4 1 0 0 1 1 1 0 F subunit of K+-transporting ATPase (Potass_KdpF) Fib_alpha PF08702.10 CBK19707.2 - 2.2 8.5 11.0 0.69 10.1 6.9 2.2 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family DUF2203 PF09969.9 CBK19707.2 - 8.7 7.1 7.4 54 4.5 7.4 2.3 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) AP_endonuc_2 PF01261.24 CBK19709.2 - 8.1e-30 103.8 0.0 1.1e-29 103.4 0.0 1.2 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel DUF2052 PF09747.9 CBK19709.2 - 8.4 6.5 13.5 1.6 8.8 8.3 2.0 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) XPG_I PF00867.18 CBK19710.2 - 1.3e-29 102.4 0.4 1.3e-29 102.4 0.4 2.0 2 0 0 2 2 2 1 XPG I-region XPG_N PF00752.17 CBK19710.2 - 4.3e-24 84.9 0.5 1.2e-23 83.5 0.2 2.0 2 0 0 2 2 2 1 XPG N-terminal domain 5_3_exonuc PF01367.20 CBK19710.2 - 2.4e-06 28.0 0.4 2.4e-05 24.8 0.0 2.7 3 0 0 3 3 3 1 5'-3' exonuclease, C-terminal SAM fold 5_3_exonuc_N PF02739.16 CBK19710.2 - 2.3e-05 24.3 0.1 0.0003 20.7 0.1 2.2 1 1 0 1 1 1 1 5'-3' exonuclease, N-terminal resolvase-like domain XRN_N PF03159.18 CBK19710.2 - 0.00037 20.0 1.0 0.00037 20.0 1.0 2.1 2 1 0 2 2 2 1 XRN 5'-3' exonuclease N-terminus NEMP PF10225.9 CBK19710.2 - 0.057 13.1 0.0 0.097 12.3 0.0 1.3 1 0 0 1 1 1 0 NEMP family Peptidase_C1 PF00112.23 CBK19711.2 - 6.5e-17 62.4 0.0 9.1e-17 61.9 0.0 1.2 1 0 0 1 1 1 1 Papain family cysteine protease PolyA_pol_RNAbd PF12627.7 CBK19714.2 - 0.0044 16.7 0.3 0.013 15.3 0.3 1.8 1 0 0 1 1 1 1 Probable RNA and SrmB- binding site of polymerase A Aa_trans PF01490.18 CBK19716.2 - 6.6e-22 77.8 19.0 8.2e-22 77.5 19.0 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 CBK19716.2 - 0.0004 19.5 15.6 0.00053 19.1 15.6 1.1 1 0 0 1 1 1 1 Tryptophan/tyrosine permease family FUSC PF04632.12 CBK19716.2 - 0.54 8.7 4.7 0.78 8.2 4.7 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF4787 PF16029.5 CBK19717.2 - 2e-19 69.4 10.1 2.5e-19 69.1 10.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4787) Glyco_hydro_20 PF00728.22 CBK19718.2 - 4.5e-68 230.2 0.0 5.3e-64 216.8 0.0 2.3 2 0 0 2 2 2 2 Glycosyl hydrolase family 20, catalytic domain DEAD PF00270.29 CBK19718.2 - 5.4e-43 146.8 0.0 8.5e-43 146.1 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CBK19718.2 - 6.4e-26 90.9 0.0 1.4e-25 89.7 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SPRY PF00622.28 CBK19718.2 - 1.3e-21 76.9 0.3 2.8e-21 75.8 0.3 1.6 1 0 0 1 1 1 1 SPRY domain ResIII PF04851.15 CBK19718.2 - 9.3e-07 29.0 0.0 0.00069 19.7 0.0 2.5 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Hat1_N PF10394.9 CBK19719.2 - 3e-24 86.1 0.0 5.7e-24 85.2 0.0 1.5 1 0 0 1 1 1 1 Histone acetyl transferase HAT1 N-terminus Glycohydro_20b2 PF14845.6 CBK19719.2 - 0.014 16.0 0.5 0.096 13.3 0.0 2.2 2 0 0 2 2 2 0 beta-acetyl hexosaminidase like zf-H2C2_2 PF13465.6 CBK19720.2 - 8.2e-07 29.2 6.2 8.2e-07 29.2 6.2 3.1 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2 PF00096.26 CBK19720.2 - 3.6e-06 27.1 18.2 0.0043 17.4 6.0 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_5 PF13909.6 CBK19720.2 - 7.8e-05 22.3 22.8 0.00033 20.4 8.5 2.7 2 1 0 2 2 2 2 C2H2-type zinc-finger domain zf-C2H2_4 PF13894.6 CBK19720.2 - 0.015 16.1 14.6 0.32 12.0 4.7 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger OrsD PF12013.8 CBK19720.2 - 0.11 13.0 11.0 0.21 12.0 1.3 2.2 2 0 0 2 2 2 0 Orsellinic acid/F9775 biosynthesis cluster protein D MMR_HSR1_Xtn PF16897.5 CBK19721.2 - 1.3e-40 137.7 1.0 2e-40 137.1 1.0 1.3 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain TGS PF02824.21 CBK19721.2 - 2.1e-23 82.1 0.0 4.1e-23 81.2 0.0 1.5 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.23 CBK19721.2 - 9.6e-20 70.8 0.0 2.1e-19 69.7 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 CBK19721.2 - 9.3e-11 41.5 0.2 9.3e-10 38.2 0.0 2.2 2 0 0 2 2 2 1 Ferrous iron transport protein B MeaB PF03308.16 CBK19721.2 - 0.0038 16.2 0.1 0.0092 15.0 0.1 1.6 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB Dynamin_N PF00350.23 CBK19721.2 - 0.0047 17.0 1.5 0.34 11.0 0.0 2.5 2 1 1 3 3 3 2 Dynamin family HSP70 PF00012.20 CBK19722.2 - 9.6e-47 159.5 13.3 3.1e-46 157.8 1.5 2.3 2 1 0 2 2 2 2 Hsp70 protein MreB_Mbl PF06723.13 CBK19722.2 - 1.7e-09 37.0 0.3 6e-08 31.9 0.1 2.7 2 1 0 2 2 2 1 MreB/Mbl protein DUF1786 PF08735.10 CBK19722.2 - 0.0011 18.3 0.0 0.0022 17.3 0.0 1.4 1 0 0 1 1 1 1 Putative pyruvate format-lyase activating enzyme (DUF1786) OmpH PF03938.14 CBK19722.2 - 0.0042 17.4 4.8 0.017 15.5 4.8 2.1 1 0 0 1 1 1 1 Outer membrane protein (OmpH-like) PilM_2 PF11104.8 CBK19722.2 - 0.0082 15.2 0.1 0.032 13.3 0.3 1.8 2 0 0 2 2 2 1 Type IV pilus assembly protein PilM; DUF3135 PF11333.8 CBK19722.2 - 0.067 13.4 5.1 0.16 12.3 5.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3135) PXA PF02194.15 CBK19722.2 - 0.08 12.9 0.2 0.39 10.7 0.1 2.1 2 0 0 2 2 2 0 PXA domain DUF4199 PF13858.6 CBK19722.2 - 0.6 10.5 11.5 3.1 8.2 4.2 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF4199) SURF2 PF05477.11 CBK19722.2 - 1 9.0 5.2 1.9 8.2 5.2 1.4 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) MscS_TM PF12794.7 CBK19723.2 - 0.65 8.8 5.0 1 8.2 5.0 1.2 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 DUF2201_N PF13203.6 CBK19723.2 - 0.83 9.2 6.3 1 8.9 6.1 1.3 1 1 0 1 1 1 0 Putative metallopeptidase domain DUF1682 PF07946.14 CBK19723.2 - 2.4 7.3 16.5 2.7 7.1 16.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) RNB PF00773.19 CBK19725.2 - 2.9e-93 312.8 0.2 4.8e-93 312.0 0.2 1.3 1 0 0 1 1 1 1 RNB domain OB_Dis3 PF17849.1 CBK19725.2 - 1.9e-21 75.9 0.0 5.8e-21 74.3 0.0 1.9 2 0 0 2 2 2 1 Dis3-like cold-shock domain 2 (CSD2) Rrp44_CSD1 PF17216.3 CBK19725.2 - 6.9e-15 55.1 0.3 2e-14 53.5 0.1 1.8 2 0 0 2 2 2 1 Rrp44-like cold shock domain Rrp44_S1 PF17215.3 CBK19725.2 - 8.6e-10 38.4 0.0 2.4e-09 37.0 0.0 1.8 1 0 0 1 1 1 1 S1 domain CSD2 PF17876.1 CBK19725.2 - 1.6e-07 31.4 0.2 8.6e-06 25.8 0.0 3.1 3 0 0 3 3 3 1 Cold shock domain GOLD_2 PF13897.6 CBK19725.2 - 9.5 6.7 8.3 0.34 11.4 0.5 2.2 2 0 0 2 2 2 0 Golgi-dynamics membrane-trafficking Aldo_ket_red PF00248.21 CBK19726.2 - 3.6e-65 220.1 0.0 6.1e-65 219.3 0.0 1.3 1 1 0 1 1 1 1 Aldo/keto reductase family Ras PF00071.22 CBK19727.2 - 4.5e-65 218.2 1.1 5.7e-65 217.9 1.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CBK19727.2 - 1.1e-33 116.0 0.7 2.1e-33 115.1 0.7 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CBK19727.2 - 1.7e-18 66.7 0.4 2.1e-18 66.4 0.4 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 CBK19727.2 - 1.9e-06 27.4 0.2 2.4e-06 27.1 0.2 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 CBK19727.2 - 1.3e-05 24.9 0.7 3.7e-05 23.4 0.1 1.9 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 CBK19727.2 - 4.4e-05 23.4 0.2 0.24 11.3 0.1 2.3 1 1 0 2 2 2 2 RsgA GTPase SRPRB PF09439.10 CBK19727.2 - 0.0007 19.1 0.3 0.0011 18.4 0.3 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 CBK19727.2 - 0.00079 19.5 0.2 0.0016 18.5 0.2 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 CBK19727.2 - 0.0043 16.6 0.1 0.017 14.7 0.1 1.9 1 1 0 1 1 1 1 Ferrous iron transport protein B G-alpha PF00503.20 CBK19727.2 - 0.0071 15.5 2.5 1.4 8.0 0.6 2.7 1 1 1 2 2 2 2 G-protein alpha subunit AAA_7 PF12775.7 CBK19727.2 - 0.0088 15.6 0.4 0.017 14.6 0.4 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region MCM PF00493.23 CBK19727.2 - 0.013 14.6 0.1 0.021 13.9 0.1 1.5 1 1 0 1 1 1 0 MCM P-loop domain AAA_5 PF07728.14 CBK19727.2 - 0.018 15.0 0.0 0.032 14.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 CBK19727.2 - 0.073 13.2 0.1 0.1 12.7 0.1 1.6 1 1 0 1 1 1 0 AAA domain AAA_24 PF13479.6 CBK19727.2 - 0.084 12.6 2.0 0.067 12.9 0.5 1.8 2 1 0 2 2 2 0 AAA domain TPP_enzyme_M PF00205.22 CBK19727.2 - 0.13 12.0 0.0 0.23 11.2 0.0 1.4 1 0 0 1 1 1 0 Thiamine pyrophosphate enzyme, central domain Ribosomal_S21e PF01249.18 CBK19728.2 - 9.9e-34 115.3 0.0 1.1e-33 115.2 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S21e CNTF PF01110.17 CBK19729.2 - 0.09 12.1 0.0 0.11 11.9 0.0 1.0 1 0 0 1 1 1 0 Ciliary neurotrophic factor ASCH PF04266.14 CBK19730.2 - 1.8e-14 54.2 0.0 4.7e-14 52.9 0.0 1.6 1 1 0 1 1 1 1 ASCH domain Stc1 PF12898.7 CBK19730.2 - 0.0011 19.5 1.1 0.0022 18.5 1.1 1.5 1 0 0 1 1 1 1 Stc1 domain UPF0565 PF10561.9 CBK19731.2 - 4.4e-23 81.9 1.9 1.7e-13 50.4 0.3 2.0 1 1 1 2 2 2 2 Uncharacterised protein family UPF0565 PGM_PMM_I PF02878.16 CBK19732.2 - 2.7e-34 117.8 0.0 5.7e-34 116.8 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.16 CBK19732.2 - 4.7e-22 78.5 0.0 1.1e-21 77.3 0.0 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_III PF02880.16 CBK19732.2 - 1.6e-14 54.1 0.1 6.9e-14 52.0 0.1 2.0 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_IV PF00408.20 CBK19732.2 - 1.5e-06 28.2 0.0 3.6e-06 27.0 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain Post_transc_reg PF13797.6 CBK19732.2 - 0.016 15.1 1.1 8 6.4 0.5 2.9 3 0 0 3 3 3 0 Post-transcriptional regulator DUF1349 PF07081.11 CBK19733.2 - 3e-55 186.7 0.2 3.4e-55 186.5 0.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1349) GH43_C2 PF17851.1 CBK19733.2 - 5.4e-07 29.5 0.0 8.4e-07 28.9 0.0 1.3 1 0 0 1 1 1 1 Beta xylosidase C-terminal Concanavalin A-like domain DUF5054 PF16477.5 CBK19736.2 - 1.3e-37 130.2 0.3 3.1e-37 128.9 0.3 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF5054) Trefoil PF00088.18 CBK19736.2 - 0.00025 20.8 2.8 0.00025 20.8 2.8 2.5 2 0 0 2 2 2 1 Trefoil (P-type) domain DUF1217 PF06748.12 CBK19736.2 - 0.027 14.5 0.0 0.046 13.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1217) Taxilin PF09728.9 CBK19737.2 - 8.7e-07 28.4 37.1 0.00038 19.7 15.4 2.0 1 1 1 2 2 2 2 Myosin-like coiled-coil protein ECM11 PF15463.6 CBK19737.2 - 0.00019 22.0 14.0 0.00048 20.7 14.0 1.8 1 1 0 1 1 1 1 Extracellular mutant protein 11 ATG16 PF08614.11 CBK19737.2 - 0.00079 19.7 33.0 0.026 14.7 21.7 2.2 1 1 1 2 2 2 1 Autophagy protein 16 (ATG16) SHE3 PF17078.5 CBK19737.2 - 0.0028 17.4 13.7 0.0028 17.4 13.7 2.3 1 1 1 2 2 2 1 SWI5-dependent HO expression protein 3 Fib_alpha PF08702.10 CBK19737.2 - 0.0059 16.8 15.5 0.0059 16.8 15.5 2.2 1 1 1 2 2 2 1 Fibrinogen alpha/beta chain family Bacillus_HBL PF05791.11 CBK19737.2 - 0.0079 16.0 14.5 0.061 13.1 3.1 2.2 1 1 1 2 2 2 1 Bacillus haemolytic enterotoxin (HBL) DivIC PF04977.15 CBK19737.2 - 0.008 15.9 4.5 0.008 15.9 4.5 4.1 1 1 3 4 4 4 1 Septum formation initiator DUF1664 PF07889.12 CBK19737.2 - 0.012 15.7 8.3 0.012 15.7 8.3 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DUF4200 PF13863.6 CBK19737.2 - 0.014 15.8 7.6 0.014 15.8 7.6 2.8 1 1 1 2 2 1 0 Domain of unknown function (DUF4200) Fez1 PF06818.15 CBK19737.2 - 0.021 15.3 14.7 0.021 15.3 14.7 2.1 1 1 1 2 2 2 0 Fez1 BLOC1_2 PF10046.9 CBK19737.2 - 0.028 14.7 24.6 0.052 13.8 11.9 2.8 1 1 2 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 AAA_13 PF13166.6 CBK19737.2 - 0.03 13.0 25.7 0.036 12.7 25.7 1.0 1 0 0 1 1 1 0 AAA domain Lebercilin PF15619.6 CBK19737.2 - 0.063 12.9 33.9 2.5 7.7 33.9 2.3 1 1 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease Seryl_tRNA_N PF02403.22 CBK19737.2 - 0.16 12.2 27.0 0.58 10.4 5.4 2.6 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain CREPT PF16566.5 CBK19737.2 - 0.2 11.8 27.3 0.44 10.7 6.9 2.2 1 1 1 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour FadA PF09403.10 CBK19737.2 - 0.2 12.2 33.5 0.64 10.5 16.7 3.6 1 1 3 4 4 4 0 Adhesion protein FadA Mod_r PF07200.13 CBK19737.2 - 0.24 11.5 30.3 0.34 11.0 8.8 2.5 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein GAS PF13851.6 CBK19737.2 - 0.27 10.6 34.0 0.8 9.0 23.7 2.3 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding DUF641 PF04859.12 CBK19737.2 - 0.27 11.5 24.5 0.061 13.7 13.9 2.6 1 1 1 2 2 1 0 Plant protein of unknown function (DUF641) Spectrin PF00435.21 CBK19737.2 - 0.28 11.7 21.9 1 9.9 9.4 2.6 1 1 2 3 3 3 0 Spectrin repeat DUF3549 PF12069.8 CBK19737.2 - 0.3 10.1 10.4 0.096 11.7 7.5 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3549) NACHT_N PF17100.5 CBK19737.2 - 0.48 10.2 18.8 0.52 10.1 8.1 2.1 1 1 1 2 2 2 0 N-terminal domain of NWD NACHT-NTPase WXG100 PF06013.12 CBK19737.2 - 0.55 10.5 8.9 0.84 9.9 2.7 3.2 2 1 1 3 3 3 0 Proteins of 100 residues with WXG KASH_CCD PF14662.6 CBK19737.2 - 0.61 9.9 34.5 2.1 8.2 34.5 1.9 1 1 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH NPV_P10 PF05531.12 CBK19737.2 - 0.66 10.5 0.1 0.66 10.5 0.1 2.9 1 1 2 3 3 3 0 Nucleopolyhedrovirus P10 protein DUF5082 PF16888.5 CBK19737.2 - 0.74 10.1 22.9 0.55 10.5 4.4 2.9 1 1 1 2 2 2 0 Domain of unknown function (DUF5082) FAD-SLDH PF12318.8 CBK19737.2 - 0.77 9.8 4.8 1.7 8.7 0.8 2.2 2 0 0 2 2 2 0 Membrane bound FAD containing D-sorbitol dehydrogenase OmpH PF03938.14 CBK19737.2 - 0.84 10.0 33.7 0.52 10.6 11.4 2.7 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) Laminin_II PF06009.12 CBK19737.2 - 0.93 9.5 20.2 0.03 14.3 8.8 2.2 2 0 0 2 2 2 0 Laminin Domain II YkyA PF10368.9 CBK19737.2 - 0.97 9.1 34.8 0.39 10.3 20.2 2.3 1 1 1 2 2 2 0 Putative cell-wall binding lipoprotein DUF664 PF04978.12 CBK19737.2 - 1 9.7 5.1 2.6 8.5 0.9 3.1 1 1 2 3 3 2 0 Protein of unknown function (DUF664) Rho_Binding PF08912.11 CBK19737.2 - 1.1 10.1 33.9 2.8 8.8 4.8 3.7 1 1 2 3 3 3 0 Rho Binding YabA PF06156.13 CBK19737.2 - 1.2 9.8 28.3 1 10.0 3.8 3.1 1 1 2 3 3 3 0 Initiation control protein YabA DUF3450 PF11932.8 CBK19737.2 - 1.4 8.2 26.4 0.22 10.8 3.9 2.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) GAT PF03127.14 CBK19737.2 - 1.5 9.2 17.7 30 5.0 8.0 3.6 1 1 1 2 2 2 0 GAT domain Com_YlbF PF06133.11 CBK19737.2 - 1.7 9.3 32.4 1.7 9.3 6.3 3.2 1 1 2 3 3 3 0 Control of competence regulator ComK, YlbF/YmcA DUF4407 PF14362.6 CBK19737.2 - 1.8 7.9 22.2 4.7 6.5 22.2 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Rx_N PF18052.1 CBK19737.2 - 1.8 8.9 14.2 2 8.7 1.7 2.8 2 1 0 2 2 2 0 Rx N-terminal domain DUF812 PF05667.11 CBK19737.2 - 3 6.6 32.6 1.6 7.5 7.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF812) Spc7 PF08317.11 CBK19737.2 - 3.3 6.5 34.4 2.4 7.0 17.5 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein TPR_MLP1_2 PF07926.12 CBK19737.2 - 3.4 7.7 36.7 10 6.2 22.4 2.8 1 1 2 3 3 3 0 TPR/MLP1/MLP2-like protein SlyX PF04102.12 CBK19737.2 - 3.5 8.3 24.3 0.14 12.8 2.0 4.1 1 1 3 4 4 4 0 SlyX KxDL PF10241.9 CBK19737.2 - 3.6 7.9 21.4 0.28 11.5 7.9 3.1 1 1 2 3 3 3 0 Uncharacterized conserved protein Csm1_N PF18504.1 CBK19737.2 - 4.6 7.7 28.4 0.2 12.0 3.3 3.5 2 1 1 3 3 3 0 Csm1 N-terminal domain PEARLI-4 PF05278.12 CBK19737.2 - 4.7 6.7 20.9 5.4 6.5 20.1 1.5 1 1 0 1 1 1 0 Arabidopsis phospholipase-like protein (PEARLI 4) DUF3584 PF12128.8 CBK19737.2 - 4.8 4.6 26.9 24 2.3 25.6 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3584) NRBF2 PF08961.10 CBK19737.2 - 5.3 6.6 22.3 2.2 7.8 7.5 2.5 1 1 0 2 2 2 0 Nuclear receptor-binding factor 2, autophagy regulator TMPIT PF07851.13 CBK19737.2 - 5.3 6.2 24.7 6.1 6.0 4.9 2.1 1 1 1 2 2 2 0 TMPIT-like protein FUSC PF04632.12 CBK19737.2 - 5.4 5.4 5.0 7.5 5.0 4.6 1.3 1 1 0 1 1 1 0 Fusaric acid resistance protein family Sulfatase_C PF14707.6 CBK19737.2 - 5.6 7.7 9.4 1.9 9.3 1.4 2.8 1 1 2 3 3 3 0 C-terminal region of aryl-sulfatase DUF745 PF05335.13 CBK19737.2 - 5.8 6.6 23.7 0.87 9.3 17.2 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF745) UPF0242 PF06785.11 CBK19737.2 - 6 6.9 32.5 22 5.1 15.2 2.6 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus HemX PF04375.14 CBK19737.2 - 6.3 6.0 23.7 0.84 8.9 7.6 2.1 1 1 1 2 2 2 0 HemX, putative uroporphyrinogen-III C-methyltransferase ADIP PF11559.8 CBK19737.2 - 6.9 6.7 31.1 0.58 10.2 6.6 2.9 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding Plk4_PB2 PF18409.1 CBK19737.2 - 7.5 7.3 13.0 7e+02 0.9 13.0 2.5 1 1 0 1 1 1 0 Polo-like Kinase 4 Polo Box 2 GAGA_bind PF06217.12 CBK19737.2 - 7.8 6.7 13.9 8.8 6.5 13.9 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family DUF3452 PF11934.8 CBK19737.2 - 8.5 5.9 8.2 12 5.5 3.6 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF3452) TMEM192 PF14802.6 CBK19737.2 - 9 5.3 9.8 4.3 6.4 0.7 2.4 2 0 0 2 2 2 0 TMEM192 family zf-C4pol PF14260.6 CBK19737.2 - 9.3 6.8 7.5 2.3 8.8 2.5 2.5 1 1 1 2 2 2 0 C4-type zinc-finger of DNA polymerase delta SLC35F PF06027.12 CBK19738.2 - 1.9e-64 218.0 26.0 2.3e-64 217.8 26.0 1.0 1 0 0 1 1 1 1 Solute carrier family 35 EamA PF00892.20 CBK19738.2 - 1.4e-11 44.7 31.1 1.1e-08 35.4 10.2 2.1 2 0 0 2 2 2 2 EamA-like transporter family CRT-like PF08627.10 CBK19738.2 - 3.1e-10 39.5 18.5 3.3e-09 36.1 18.6 2.2 1 1 0 1 1 1 1 CRT-like, chloroquine-resistance transporter-like Mg_trans_NIPA PF05653.14 CBK19738.2 - 2e-05 23.9 5.3 2e-05 23.9 5.3 2.3 1 1 1 2 2 2 1 Magnesium transporter NIPA EmrE PF13536.6 CBK19738.2 - 0.00043 20.0 15.5 0.0017 18.0 16.0 1.8 1 1 0 1 1 1 1 Putative multidrug resistance efflux transporter TPT PF03151.16 CBK19738.2 - 0.12 11.7 20.0 0.15 11.4 20.0 1.1 1 0 0 1 1 1 0 Triose-phosphate Transporter family Nuc_sug_transp PF04142.15 CBK19738.2 - 0.33 10.1 22.7 0.057 12.6 18.5 1.7 1 1 1 2 2 2 0 Nucleotide-sugar transporter TMEM234 PF10639.9 CBK19738.2 - 1.4 9.0 9.2 3 7.9 0.1 3.0 2 2 0 2 2 2 0 Putative transmembrane family 234 Wzy_C PF04932.15 CBK19738.2 - 8.2 6.0 10.8 0.54 9.9 0.2 3.1 3 1 0 3 3 3 0 O-Antigen ligase WD40 PF00400.32 CBK19740.2 - 6.9e-12 45.7 9.5 4.3e-05 24.2 0.1 6.2 6 0 0 6 6 6 4 WD domain, G-beta repeat Pyr_redox_2 PF07992.14 CBK19741.2 - 1.3e-59 201.9 0.2 1.7e-59 201.5 0.2 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 CBK19741.2 - 7.3e-18 64.9 8.2 2e-17 63.5 0.9 3.2 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 CBK19741.2 - 1.1e-12 47.9 0.1 1.4e-11 44.3 0.0 2.2 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 CBK19741.2 - 1.6e-09 38.0 0.0 4.4e-09 36.6 0.0 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain NAD_binding_8 PF13450.6 CBK19741.2 - 2.2e-08 34.2 0.3 0.0022 18.2 0.0 2.9 3 0 0 3 3 2 2 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 CBK19741.2 - 1.2e-06 27.5 4.5 0.0053 15.5 0.1 3.8 3 1 1 4 4 4 2 HI0933-like protein Lycopene_cycl PF05834.12 CBK19741.2 - 1.5e-05 24.3 2.9 0.099 11.7 0.1 3.0 2 1 1 3 3 3 2 Lycopene cyclase protein Rhodanese PF00581.20 CBK19741.2 - 3.9e-05 24.1 0.0 0.0017 18.9 0.0 3.1 3 1 0 3 3 3 1 Rhodanese-like domain DAO PF01266.24 CBK19741.2 - 7.9e-05 22.4 2.0 0.019 14.5 0.1 3.7 4 0 0 4 4 4 1 FAD dependent oxidoreductase NAD_binding_7 PF13241.6 CBK19741.2 - 0.00012 22.5 0.5 0.059 13.8 0.1 2.6 2 0 0 2 2 2 1 Putative NAD(P)-binding DUF1188 PF06690.11 CBK19741.2 - 0.00056 19.5 0.1 0.0013 18.3 0.0 1.6 2 0 0 2 2 1 1 Protein of unknown function (DUF1188) AlaDh_PNT_C PF01262.21 CBK19741.2 - 0.00077 18.8 1.1 0.014 14.7 0.1 2.4 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.18 CBK19741.2 - 0.00085 19.3 0.1 0.0014 18.5 0.1 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_9 PF13454.6 CBK19741.2 - 0.00099 19.1 2.1 9.4 6.2 0.2 4.1 3 1 1 4 4 4 0 FAD-NAD(P)-binding TrkA_N PF02254.18 CBK19741.2 - 0.0035 17.6 0.3 0.033 14.4 0.0 2.5 2 0 0 2 2 2 1 TrkA-N domain K_oxygenase PF13434.6 CBK19741.2 - 0.0042 16.3 0.1 0.0091 15.2 0.0 1.6 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Shikimate_DH PF01488.20 CBK19741.2 - 0.0064 16.6 0.1 0.014 15.5 0.1 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Amino_oxidase PF01593.24 CBK19741.2 - 0.01 15.2 2.3 1.7 7.8 0.1 3.0 2 1 0 3 3 3 0 Flavin containing amine oxidoreductase NAD_binding_2 PF03446.15 CBK19741.2 - 0.02 15.1 0.1 0.042 14.0 0.1 1.5 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase ApbA PF02558.16 CBK19741.2 - 0.02 14.5 0.2 0.84 9.3 0.1 2.7 2 1 0 2 2 2 0 Ketopantoate reductase PanE/ApbA FAD_binding_3 PF01494.19 CBK19741.2 - 0.057 12.7 0.1 0.12 11.6 0.1 1.5 1 0 0 1 1 1 0 FAD binding domain AdoHcyase_NAD PF00670.21 CBK19741.2 - 0.068 13.2 0.6 0.43 10.6 0.1 2.1 2 0 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain FAD_binding_2 PF00890.24 CBK19741.2 - 0.076 12.1 3.3 0.84 8.6 0.1 2.8 3 0 0 3 3 3 0 FAD binding domain RAP PF08373.10 CBK19741.2 - 0.1 12.7 0.0 0.2 11.8 0.0 1.4 1 0 0 1 1 1 0 RAP domain 2-Hacid_dh_C PF02826.19 CBK19741.2 - 0.12 11.8 0.0 0.3 10.4 0.0 1.7 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.14 CBK19741.2 - 0.29 10.7 2.3 0.45 10.1 0.2 2.3 3 0 0 3 3 3 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain DNA_pol_E_B PF04042.16 CBK19742.2 - 1.3e-06 28.0 0.0 1.7e-06 27.6 0.0 1.1 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B MFS_1 PF07690.16 CBK19744.2 - 8.2e-22 77.6 23.8 1.1e-12 47.6 0.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily UNC-93 PF05978.16 CBK19744.2 - 2.6e-15 56.5 6.8 2.6e-15 56.5 6.8 2.4 2 1 0 2 2 2 1 Ion channel regulatory protein UNC-93 MFS_2 PF13347.6 CBK19744.2 - 4.8e-07 28.7 22.6 0.00097 17.8 0.1 2.9 1 1 2 3 3 3 2 MFS/sugar transport protein Cytochrom_B561 PF03188.16 CBK19744.2 - 0.011 15.9 0.4 0.011 15.9 0.4 3.1 3 0 0 3 3 3 0 Eukaryotic cytochrome b561 YccF PF03733.13 CBK19744.2 - 0.1 13.4 0.3 0.1 13.4 0.3 4.5 4 1 1 5 5 5 0 Inner membrane component domain RRM_1 PF00076.22 CBK19746.2 - 5.3e-18 64.6 0.0 8.9e-18 63.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCHC PF00098.23 CBK19746.2 - 0.00055 19.9 3.6 0.00088 19.2 3.6 1.3 1 0 0 1 1 1 1 Zinc knuckle RRM_5 PF13893.6 CBK19746.2 - 0.0014 18.2 0.0 0.002 17.7 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RNA_bind PF08675.11 CBK19746.2 - 0.017 15.1 0.1 0.044 13.8 0.1 1.7 1 1 0 1 1 1 0 RNA binding domain zf-CCHC_3 PF13917.6 CBK19746.2 - 0.023 14.7 2.1 0.038 13.9 2.1 1.4 1 0 0 1 1 1 0 Zinc knuckle BRAP2 PF07576.12 CBK19746.2 - 0.042 14.1 0.0 0.06 13.6 0.0 1.2 1 0 0 1 1 1 0 BRCA1-associated protein 2 Nup35_RRM_2 PF14605.6 CBK19746.2 - 0.047 13.7 0.0 0.085 12.9 0.0 1.4 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif DUF1866 PF08952.11 CBK19746.2 - 0.075 12.9 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1866) RRM_occluded PF16842.5 CBK19746.2 - 0.082 12.8 0.0 0.15 12.0 0.0 1.4 1 1 0 1 1 1 0 Occluded RNA-recognition motif Zfx_Zfy_act PF04704.13 CBK19746.2 - 0.26 10.4 1.0 4.8 6.2 0.2 2.0 1 1 1 2 2 2 0 Zfx / Zfy transcription activation region PWI PF01480.17 CBK19747.2 - 7.2e-23 80.7 0.2 1.4e-22 79.7 0.2 1.5 1 0 0 1 1 1 1 PWI domain LPD22 PF18834.1 CBK19747.2 - 0.0039 17.4 0.5 0.0073 16.5 0.5 1.3 1 0 0 1 1 1 1 Large polyvalent protein associated domain 22 IHABP4_N PF16174.5 CBK19747.2 - 0.0093 16.6 12.9 0.018 15.7 12.9 1.4 1 0 0 1 1 1 1 Intracellular hyaluronan-binding protein 4 N-terminal RSRP PF17069.5 CBK19747.2 - 7.8 6.0 44.4 13 5.2 44.4 1.4 1 0 0 1 1 1 0 Arginine/Serine-Rich protein 1 ABC_tran PF00005.27 CBK19748.2 - 3.8e-47 160.3 1.2 1.7e-23 83.6 0.0 3.2 3 0 0 3 3 3 2 ABC transporter AAA_21 PF13304.6 CBK19748.2 - 9.7e-17 61.7 7.9 3e-05 24.0 0.0 4.4 3 1 0 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 CBK19748.2 - 9.1e-14 51.4 1.3 1.2e-05 24.8 0.0 4.2 4 0 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 CBK19748.2 - 3.7e-08 33.0 0.1 0.01 15.5 0.0 3.3 3 0 0 3 3 3 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 CBK19748.2 - 1.1e-07 31.9 0.0 0.0084 16.0 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase ABC_tran_Xtn PF12848.7 CBK19748.2 - 7.9e-07 29.0 3.3 7.9e-07 29.0 3.3 2.5 4 0 0 4 4 1 1 ABC transporter AAA_22 PF13401.6 CBK19748.2 - 1.1e-05 25.8 0.7 1.9 8.8 0.0 4.7 3 1 0 3 3 3 2 AAA domain AAA_16 PF13191.6 CBK19748.2 - 1.1e-05 25.9 0.6 0.093 13.1 0.0 2.7 2 1 0 2 2 2 2 AAA ATPase domain AAA_15 PF13175.6 CBK19748.2 - 5.4e-05 23.1 9.1 1 9.0 0.0 5.1 3 1 1 5 5 5 1 AAA ATPase domain AAA_24 PF13479.6 CBK19748.2 - 5.6e-05 23.0 0.1 0.081 12.6 0.0 3.1 3 0 0 3 3 3 1 AAA domain MMR_HSR1 PF01926.23 CBK19748.2 - 6.3e-05 23.0 0.2 0.069 13.2 0.0 3.6 4 0 0 4 4 3 1 50S ribosome-binding GTPase RNA_helicase PF00910.22 CBK19748.2 - 0.00012 22.4 0.0 0.68 10.3 0.0 2.7 2 0 0 2 2 2 2 RNA helicase AAA_25 PF13481.6 CBK19748.2 - 0.00016 21.3 0.0 0.35 10.4 0.0 3.1 3 0 0 3 3 3 2 AAA domain NACHT PF05729.12 CBK19748.2 - 0.0002 21.3 0.0 0.93 9.4 0.0 2.8 2 0 0 2 2 2 2 NACHT domain NB-ARC PF00931.22 CBK19748.2 - 0.00039 19.7 0.9 0.11 11.7 0.0 3.4 4 1 0 4 4 3 1 NB-ARC domain DUF87 PF01935.17 CBK19748.2 - 0.00097 19.3 9.5 0.54 10.3 0.1 4.2 3 1 1 4 4 4 1 Helicase HerA, central domain MeaB PF03308.16 CBK19748.2 - 0.0011 18.0 0.1 0.26 10.2 0.0 2.6 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_5 PF07728.14 CBK19748.2 - 0.0015 18.5 0.4 1.6 8.7 0.0 3.7 4 0 0 4 4 3 1 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 CBK19748.2 - 0.0023 18.5 1.8 6.3 7.4 0.0 3.8 4 0 0 4 4 3 0 AAA domain AAA_30 PF13604.6 CBK19748.2 - 0.0043 16.8 0.0 1.4 8.6 0.0 2.7 2 1 0 2 2 2 1 AAA domain SbcCD_C PF13558.6 CBK19748.2 - 0.0054 16.9 0.4 0.34 11.2 0.1 3.4 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit MIP-T3_C PF17749.1 CBK19748.2 - 0.0061 16.5 8.8 0.13 12.3 2.2 2.6 2 0 0 2 2 2 1 Microtubule-binding protein MIP-T3 C-terminal region AAA_33 PF13671.6 CBK19748.2 - 0.0083 16.3 0.0 4.7 7.4 0.0 2.9 3 0 0 3 3 2 0 AAA domain AAA_28 PF13521.6 CBK19748.2 - 0.0088 16.3 0.3 3.5 7.9 0.0 2.9 3 0 0 3 3 2 1 AAA domain NTPase_1 PF03266.15 CBK19748.2 - 0.0091 15.9 0.0 3.5 7.5 0.0 2.7 2 0 0 2 2 2 1 NTPase FlxA PF14282.6 CBK19748.2 - 0.01 15.8 3.5 0.01 15.8 3.5 2.5 2 0 0 2 2 2 0 FlxA-like protein AAA_7 PF12775.7 CBK19748.2 - 0.013 15.0 0.0 3.6 7.1 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region SRP54 PF00448.22 CBK19748.2 - 0.013 15.1 0.0 3 7.4 0.0 2.5 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA PF00004.29 CBK19748.2 - 0.014 15.8 3.6 5.9 7.3 0.0 4.0 3 2 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) Roc PF08477.13 CBK19748.2 - 0.019 15.2 0.0 2.6 8.3 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_23 PF13476.6 CBK19748.2 - 0.037 14.5 18.2 2.2 8.8 0.0 4.5 5 0 0 5 5 4 0 AAA domain ThylakoidFormat PF11264.8 CBK19748.2 - 0.053 13.2 0.3 0.14 11.9 0.3 1.6 1 0 0 1 1 1 0 Thylakoid formation protein Pox_A32 PF04665.12 CBK19748.2 - 0.11 11.9 0.9 13 5.1 0.0 2.6 3 0 0 3 3 2 0 Poxvirus A32 protein OmpH PF03938.14 CBK19748.2 - 0.31 11.4 11.6 0.26 11.6 4.6 2.4 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) DUF4407 PF14362.6 CBK19748.2 - 0.56 9.5 3.8 11 5.2 0.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) DUF148 PF02520.17 CBK19748.2 - 1.7 8.8 5.6 0.44 10.7 0.4 2.3 2 0 0 2 2 2 0 Domain of unknown function DUF148 GrpE PF01025.19 CBK19748.2 - 2.4 7.8 11.7 0.14 11.8 1.6 2.4 2 0 0 2 2 2 0 GrpE Seryl_tRNA_N PF02403.22 CBK19748.2 - 3.3 8.0 19.2 0.033 14.4 3.2 2.7 3 0 0 3 3 2 0 Seryl-tRNA synthetase N-terminal domain MerR-DNA-bind PF09278.11 CBK19748.2 - 4.4 7.9 9.3 2.1 8.9 4.4 2.5 2 0 0 2 2 2 0 MerR, DNA binding HAUS6_N PF14661.6 CBK19748.2 - 4.4 6.8 6.8 0.56 9.8 1.8 1.9 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus Helo_like_N PF17111.5 CBK19748.2 - 5.2 6.4 9.7 9.8 5.5 1.5 3.0 3 0 0 3 3 3 0 Fungal N-terminal domain of STAND proteins Atg14 PF10186.9 CBK19748.2 - 6.9 5.6 6.6 6 5.8 1.0 2.1 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 HSP70 PF00012.20 CBK19749.2 - 6e-269 893.3 12.1 6.8e-269 893.1 12.1 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 CBK19749.2 - 1.2e-14 53.9 1.6 3e-13 49.3 0.2 2.6 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.16 CBK19749.2 - 0.00041 20.1 0.0 0.0011 18.8 0.0 1.8 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain BcrAD_BadFG PF01869.20 CBK19749.2 - 0.004 16.7 0.0 0.24 10.9 0.0 2.7 2 1 1 3 3 3 2 BadF/BadG/BcrA/BcrD ATPase family FtsA PF14450.6 CBK19749.2 - 0.032 14.7 9.4 0.24 11.9 0.3 3.7 3 3 0 3 3 3 0 Cell division protein FtsA Peptidase_M22 PF00814.25 CBK19749.2 - 0.14 11.8 0.8 0.93 9.1 0.0 2.3 2 0 0 2 2 2 0 Glycoprotease family RMI1_C PF16099.5 CBK19749.2 - 0.33 10.8 2.2 0.42 10.5 0.0 2.3 2 1 0 2 2 2 0 Recq-mediated genome instability protein 1, C-terminal OB-fold Phasin PF05597.11 CBK19749.2 - 3 7.9 11.9 0.16 12.0 5.5 2.2 3 0 0 3 3 3 0 Poly(hydroxyalcanoate) granule associated protein (phasin) TMPIT PF07851.13 CBK19749.2 - 6.1 6.0 8.3 11 5.1 8.3 1.4 1 0 0 1 1 1 0 TMPIT-like protein CRAL_TRIO PF00650.20 CBK19750.2 - 2.4e-10 40.4 0.1 0.00044 20.0 0.0 2.2 2 0 0 2 2 2 2 CRAL/TRIO domain PH PF00169.29 CBK19750.2 - 0.00039 20.9 0.5 0.00076 20.0 0.5 1.5 1 0 0 1 1 1 1 PH domain T3SS_needle_reg PF09025.10 CBK19750.2 - 0.056 13.4 0.0 0.1 12.6 0.0 1.3 1 0 0 1 1 1 0 YopR, type III needle-polymerisation regulator PH_11 PF15413.6 CBK19750.2 - 1.3 9.5 4.2 0.49 10.8 1.6 1.7 2 0 0 2 2 2 0 Pleckstrin homology domain Melibiase_2 PF16499.5 CBK19751.2 - 2.3e-73 246.8 4.7 3.2e-73 246.4 4.7 1.2 1 0 0 1 1 1 1 Alpha galactosidase A Melibiase_C PF17801.1 CBK19751.2 - 2.4e-17 62.8 0.0 6.7e-17 61.3 0.0 1.8 1 0 0 1 1 1 1 Alpha galactosidase C-terminal beta sandwich domain Melibiase PF02065.18 CBK19751.2 - 2.5e-05 23.4 0.0 5.4e-05 22.3 0.0 1.5 1 0 0 1 1 1 1 Melibiase Melibiase_2_C PF17450.2 CBK19751.2 - 0.0048 17.1 0.0 0.011 15.9 0.0 1.6 1 0 0 1 1 1 1 Alpha galactosidase A C-terminal beta sandwich domain PAP_central PF04928.17 CBK19752.2 - 6.7e-47 159.5 0.3 2.2e-45 154.6 0.3 2.2 1 1 0 1 1 1 1 Poly(A) polymerase central domain PAP_RNA-bind PF04926.15 CBK19752.2 - 1.8e-16 60.3 0.9 7.4e-13 48.5 1.2 2.4 1 1 1 2 2 2 2 Poly(A) polymerase predicted RNA binding domain NTP_transf_2 PF01909.23 CBK19752.2 - 6.5e-05 23.2 0.0 0.00019 21.6 0.0 1.9 1 0 0 1 1 1 1 Nucleotidyltransferase domain NB-ARC PF00931.22 CBK19752.2 - 0.059 12.6 0.0 0.1 11.7 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain RRM_1 PF00076.22 CBK19753.2 - 3.5e-17 62.0 0.2 6e-15 54.8 0.1 2.1 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CBK19753.2 - 2.5e-07 30.7 0.1 0.00022 21.3 0.1 2.5 2 1 0 2 2 2 2 RNA recognition motif RL PF17797.1 CBK19753.2 - 0.1 12.6 0.0 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 RL domain Ras PF00071.22 CBK19754.2 - 1.4e-59 200.3 0.0 1.8e-59 200.0 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CBK19754.2 - 6e-37 126.5 0.0 8.7e-37 126.0 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CBK19754.2 - 2.3e-14 53.2 0.1 3e-14 52.8 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 CBK19754.2 - 1.1e-07 31.5 0.0 1.4e-07 31.1 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 CBK19754.2 - 4.2e-05 23.6 0.0 6.1e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 CBK19754.2 - 9.5e-05 22.0 0.1 0.00053 19.6 0.1 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 CBK19754.2 - 0.0002 21.3 0.0 0.45 10.4 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase Gtr1_RagA PF04670.12 CBK19754.2 - 0.00052 19.4 0.1 0.00067 19.1 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region FeoB_N PF02421.18 CBK19754.2 - 0.0038 16.8 0.1 0.11 12.1 0.1 2.2 1 1 0 1 1 1 1 Ferrous iron transport protein B AAA_22 PF13401.6 CBK19754.2 - 0.0058 16.9 0.0 0.12 12.7 0.0 2.6 1 1 1 2 2 2 1 AAA domain AAA_7 PF12775.7 CBK19754.2 - 0.0074 15.8 0.0 0.014 14.9 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_24 PF13479.6 CBK19754.2 - 0.024 14.4 0.2 0.03 14.0 0.2 1.5 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 CBK19754.2 - 0.032 14.7 0.0 0.25 11.8 0.0 2.4 1 1 1 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 CBK19754.2 - 0.077 13.4 0.0 0.15 12.4 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain AAA_5 PF07728.14 CBK19754.2 - 0.092 12.8 0.0 0.55 10.2 0.0 2.1 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) TniB PF05621.11 CBK19754.2 - 0.12 11.8 0.0 0.39 10.1 0.0 1.8 2 1 1 3 3 3 0 Bacterial TniB protein AAA_33 PF13671.6 CBK19754.2 - 0.14 12.3 0.0 0.19 11.9 0.0 1.2 1 0 0 1 1 1 0 AAA domain Got1 PF04178.12 CBK19755.2 - 5.2e-12 46.2 13.0 7.1e-12 45.7 12.2 1.7 2 1 0 2 2 2 1 Got1/Sft2-like family DUF308 PF03729.13 CBK19755.2 - 0.0039 17.5 5.9 0.0039 17.5 5.9 2.4 1 1 0 2 2 2 1 Short repeat of unknown function (DUF308) DUF373 PF04123.13 CBK19755.2 - 0.014 14.9 3.5 0.016 14.6 3.5 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF373) DUF1788 PF08747.11 CBK19755.2 - 0.21 11.6 0.6 0.37 10.8 0.3 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF1788) Prefoldin_2 PF01920.20 CBK19756.2 - 9.8e-13 48.0 4.4 1.2e-12 47.7 4.4 1.1 1 0 0 1 1 1 1 Prefoldin subunit DUF4200 PF13863.6 CBK19756.2 - 0.0065 16.9 2.0 0.026 14.9 0.2 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4200) CdvA PF18822.1 CBK19756.2 - 0.021 14.7 3.3 0.75 9.6 0.2 2.1 2 0 0 2 2 2 0 CdvA-like coiled-coil domain DUF5531 PF17671.1 CBK19756.2 - 0.07 13.0 0.3 0.079 12.8 0.3 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5531) AAA_9 PF12781.7 CBK19756.2 - 0.19 10.8 3.1 4.9 6.2 0.4 2.0 2 0 0 2 2 2 0 ATP-binding dynein motor region FIN1 PF17300.2 CBK19756.2 - 0.33 10.4 3.8 1.5 8.3 3.6 1.9 1 1 0 1 1 1 0 Filaments in between nuclei protein-1 Uso1_p115_C PF04871.13 CBK19756.2 - 0.49 10.8 5.7 5 7.5 5.8 2.0 1 1 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region Ribosomal_S25 PF03297.15 CBK19757.2 - 2.6e-22 78.9 0.2 3.1e-22 78.7 0.2 1.1 1 0 0 1 1 1 1 S25 ribosomal protein AbiEi_4 PF13338.6 CBK19757.2 - 0.0087 16.2 0.1 0.014 15.5 0.1 1.4 1 0 0 1 1 1 1 Transcriptional regulator, AbiEi antitoxin Rhodanese PF00581.20 CBK19758.2 - 7.6e-21 74.6 0.0 3.1e-11 43.8 0.0 2.2 2 0 0 2 2 2 2 Rhodanese-like domain WD40 PF00400.32 CBK19759.2 - 0.83 10.6 2.8 61 4.7 0.0 4.0 4 1 0 4 4 4 0 WD domain, G-beta repeat DSHCT PF08148.12 CBK19760.2 - 2.9e-41 140.9 0.1 5.7e-41 139.9 0.1 1.5 1 0 0 1 1 1 1 DSHCT (NUC185) domain DEAD PF00270.29 CBK19760.2 - 3.3e-16 59.5 0.0 7.5e-16 58.4 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 CBK19760.2 - 0.00026 21.1 0.1 0.0011 19.0 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 CBK19760.2 - 0.0099 16.2 0.0 0.027 14.8 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 CBK19760.2 - 0.028 14.7 0.7 0.7 10.2 0.0 3.2 3 1 0 3 3 3 0 AAA domain VWA PF00092.28 CBK19761.2 - 5.3e-26 91.9 0.7 7.1e-26 91.5 0.7 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 CBK19761.2 - 1.1e-14 55.0 0.1 1.9e-14 54.2 0.1 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.6 CBK19761.2 - 0.00019 21.4 0.0 0.00039 20.4 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain TIG PF01833.24 CBK19761.2 - 0.0016 18.5 0.0 0.0034 17.4 0.0 1.6 1 0 0 1 1 1 1 IPT/TIG domain Anth_Ig PF05587.13 CBK19761.2 - 0.004 17.4 0.1 0.031 14.6 0.1 2.2 1 1 0 1 1 1 1 Anthrax receptor extracellular domain TIG_plexin PF17960.1 CBK19761.2 - 0.0045 17.0 0.0 0.01 15.8 0.0 1.5 1 0 0 1 1 1 1 TIG domain OAD_gamma PF04277.13 CBK19761.2 - 0.042 14.4 0.1 0.087 13.4 0.1 1.5 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain DUF2201 PF09967.9 CBK19761.2 - 0.11 12.6 0.0 0.22 11.7 0.0 1.5 1 0 0 1 1 1 0 VWA-like domain (DUF2201) ICMT PF04140.14 CBK19761.2 - 0.27 11.7 1.4 22 5.5 0.0 2.3 2 0 0 2 2 2 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family Ribosomal_L15e PF00827.17 CBK19762.2 - 2.9e-80 268.5 8.4 2.2e-79 265.6 8.4 1.9 1 1 0 1 1 1 1 Ribosomal L15 DUF1647 PF07801.11 CBK19763.2 - 0.057 13.2 1.1 0.54 10.0 1.1 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1647) Ribosomal_L22 PF00237.19 CBK19764.2 - 3.8e-33 113.8 0.2 6.1e-33 113.1 0.2 1.3 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e POR_N PF01855.19 CBK19766.2 - 2.4e-58 197.6 0.1 4.4e-58 196.8 0.1 1.4 1 0 0 1 1 1 1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg POR PF01558.18 CBK19766.2 - 1.3e-28 100.3 0.3 3.3e-28 98.9 0.3 1.7 1 0 0 1 1 1 1 Pyruvate ferredoxin/flavodoxin oxidoreductase PFOR_II PF17147.4 CBK19766.2 - 6e-13 49.0 0.0 1.9e-12 47.4 0.0 1.9 1 0 0 1 1 1 1 Pyruvate:ferredoxin oxidoreductase core domain II EKR PF10371.9 CBK19766.2 - 1.5e-09 37.5 0.0 5e-09 35.8 0.0 1.9 1 0 0 1 1 1 1 Domain of unknown function Fer4_7 PF12838.7 CBK19766.2 - 7.2e-09 36.1 7.0 7.2e-09 36.1 7.0 2.2 2 0 0 2 2 1 1 4Fe-4S dicluster domain Fer4_16 PF13484.6 CBK19766.2 - 9e-09 36.1 15.5 1.2e-07 32.5 6.4 2.6 1 1 1 2 2 2 2 4Fe-4S double cluster binding domain TPP_enzyme_C PF02775.21 CBK19766.2 - 2.1e-08 34.1 0.4 7.1e-08 32.4 0.4 1.9 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Fer4_10 PF13237.6 CBK19766.2 - 9.1e-08 32.1 7.7 0.0024 18.0 0.9 2.7 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4 PF00037.27 CBK19766.2 - 3e-07 30.0 18.9 0.00013 21.6 1.4 3.0 3 0 0 3 3 3 2 4Fe-4S binding domain Fer4_9 PF13187.6 CBK19766.2 - 6.1e-07 29.5 19.0 3e-06 27.3 8.4 2.5 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_6 PF12837.7 CBK19766.2 - 4.2e-05 23.4 19.4 0.0023 17.9 3.0 3.0 3 0 0 3 3 3 2 4Fe-4S binding domain Fer4_21 PF14697.6 CBK19766.2 - 8.4e-05 22.6 15.3 0.0026 17.8 15.3 2.9 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_8 PF13183.6 CBK19766.2 - 0.0001 22.7 6.6 0.0001 22.7 6.6 2.2 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_2 PF12797.7 CBK19766.2 - 0.00016 21.5 19.3 0.0068 16.4 3.5 3.2 3 0 0 3 3 3 2 4Fe-4S binding domain Fer4_17 PF13534.6 CBK19766.2 - 0.0029 18.1 12.4 0.012 16.2 11.1 2.6 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_13 PF13370.6 CBK19766.2 - 0.044 14.3 11.0 0.62 10.7 1.2 3.1 2 0 0 2 2 2 0 4Fe-4S single cluster domain of Ferredoxin I Fer4_18 PF13746.6 CBK19766.2 - 0.071 13.3 11.7 0.47 10.7 9.4 2.7 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_4 PF12800.7 CBK19766.2 - 0.34 11.5 18.9 0.042 14.4 3.5 3.0 3 0 0 3 3 2 0 4Fe-4S binding domain Fer4_3 PF12798.7 CBK19766.2 - 1.9 9.6 22.2 1.3 10.1 6.6 2.8 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_15 PF13459.6 CBK19766.2 - 2 9.2 8.2 14 6.5 0.7 2.9 2 0 0 2 2 2 0 4Fe-4S single cluster domain Collagen PF01391.18 CBK19768.2 - 0.001 18.8 2.6 0.0019 17.9 2.6 1.3 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) Torus PF16131.5 CBK19768.2 - 0.048 14.4 0.8 2.1 9.1 0.1 2.4 2 0 0 2 2 2 0 Torus domain Fcf2 PF08698.11 CBK19769.2 - 1.9e-22 79.4 0.4 3.7e-22 78.5 0.4 1.5 1 0 0 1 1 1 1 Fcf2 pre-rRNA processing AMP-binding PF00501.28 CBK19770.2 - 1.9e-73 247.5 0.0 2.3e-73 247.2 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme UQ_con PF00179.26 CBK19771.2 - 1.7e-13 50.5 0.7 2.5e-13 49.9 0.7 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme SopD PF11047.8 CBK19771.2 - 0.011 15.0 0.1 0.012 14.8 0.1 1.1 1 0 0 1 1 1 0 Salmonella outer protein D BTB PF00651.31 CBK19772.2 - 8.8e-06 25.9 0.2 1.3e-05 25.4 0.2 1.4 1 1 0 1 1 1 1 BTB/POZ domain Skp1_POZ PF03931.15 CBK19772.2 - 0.0011 19.1 0.8 0.0029 17.8 0.8 1.7 1 1 0 1 1 1 1 Skp1 family, tetramerisation domain Cystatin PF00031.21 CBK19773.2 - 5.9e-05 23.3 0.0 6.8e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 Cystatin domain VPS13_C PF16909.5 CBK19774.2 - 7.6e-10 38.9 0.1 1.5e-09 37.9 0.1 1.5 1 0 0 1 1 1 1 Vacuolar-sorting-associated 13 protein C-terminal Chorein_N PF12624.7 CBK19775.2 - 1e-14 54.7 1.9 1.2e-14 54.4 1.9 1.1 1 0 0 1 1 1 1 N-terminal region of Chorein or VPS13 NifU PF01106.17 CBK19776.2 - 7.6e-06 26.0 0.0 1.3e-05 25.2 0.0 1.3 1 0 0 1 1 1 1 NifU-like domain MCU PF04678.13 CBK19776.2 - 0.17 12.0 1.7 0.17 11.9 1.7 1.1 1 0 0 1 1 1 0 Mitochondrial calcium uniporter eIF-6 PF01912.18 CBK19777.2 - 7e-74 247.5 1.8 8e-74 247.3 0.8 1.6 2 0 0 2 2 2 1 eIF-6 family ApbA PF02558.16 CBK19777.2 - 6.8e-22 77.7 0.1 2.1e-21 76.1 0.0 1.8 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.11 CBK19777.2 - 4.5e-18 65.7 0.1 8.7e-18 64.7 0.1 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal PAS_8 PF13188.7 CBK19777.2 - 0.06 13.4 0.0 0.15 12.2 0.0 1.6 1 0 0 1 1 1 0 PAS domain CH PF00307.31 CBK19779.2 - 0.0003 20.9 0.0 0.00043 20.4 0.0 1.3 1 0 0 1 1 1 1 Calponin homology (CH) domain CAMSAP_CH PF11971.8 CBK19779.2 - 0.03 14.1 0.1 0.072 12.9 0.0 1.7 1 1 0 1 1 1 0 CAMSAP CH domain HSP70 PF00012.20 CBK19781.2 - 3e-61 207.4 0.0 3.9e-61 207.0 0.0 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 CBK19781.2 - 6.1e-15 54.9 0.0 1.3e-14 53.8 0.0 1.4 1 1 0 1 1 1 1 MreB/Mbl protein PilM_2 PF11104.8 CBK19781.2 - 0.0017 17.5 0.0 0.76 8.7 0.0 2.2 1 1 1 2 2 2 2 Type IV pilus assembly protein PilM; DDR PF08841.10 CBK19781.2 - 0.0038 16.3 0.2 0.73 8.8 0.0 2.7 2 1 1 3 3 3 2 Diol dehydratase reactivase ATPase-like domain MutL PF13941.6 CBK19781.2 - 0.096 11.3 0.0 0.27 9.8 0.0 1.6 2 0 0 2 2 2 0 MutL protein Actin PF00022.19 CBK19781.2 - 0.14 10.7 0.0 12 4.4 0.0 2.1 2 0 0 2 2 2 0 Actin Carboxyl_trans PF01039.22 CBK19782.2 - 4.9e-190 632.4 0.1 5.8e-190 632.1 0.1 1.0 1 0 0 1 1 1 1 Carboxyl transferase domain MdcE PF06833.11 CBK19782.2 - 0.0093 15.5 0.0 0.03 13.8 0.0 1.8 3 0 0 3 3 3 1 Malonate decarboxylase gamma subunit (MdcE) MSC PF09402.10 CBK19783.2 - 8.1e-08 32.1 9.4 5.1e-07 29.5 9.3 2.0 1 1 0 1 1 1 1 Man1-Src1p-C-terminal domain cEGF PF12662.7 CBK19783.2 - 0.032 14.1 0.2 0.032 14.1 0.2 2.5 3 0 0 3 3 3 0 Complement Clr-like EGF-like EB PF01683.18 CBK19783.2 - 0.048 14.0 8.2 0.048 14.0 8.2 1.8 2 0 0 2 2 2 0 EB module hEGF PF12661.7 CBK19783.2 - 1.8 9.3 9.1 0.93 10.2 6.0 2.3 2 0 0 2 2 2 0 Human growth factor-like EGF Tme5_EGF_like PF09064.10 CBK19783.2 - 1.8 8.5 8.1 1.7 8.6 1.3 2.5 1 1 1 2 2 2 0 Thrombomodulin like fifth domain, EGF-like ARID PF01388.21 CBK19784.2 - 2.8e-14 53.6 0.0 4.7e-14 52.8 0.0 1.3 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain zf-CW PF07496.15 CBK19784.2 - 9.3e-13 48.0 1.1 3.5e-12 46.1 1.0 2.0 2 0 0 2 2 2 1 CW-type Zinc Finger Ribosomal_L13e PF01294.18 CBK19785.2 - 1.8e-74 249.5 0.5 2.4e-74 249.1 0.5 1.2 1 0 0 1 1 1 1 Ribosomal protein L13e WD40 PF00400.32 CBK19786.2 - 0.0019 19.0 0.1 0.025 15.4 0.0 2.7 3 0 0 3 3 3 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBK19786.2 - 0.0039 17.5 0.0 0.0056 17.0 0.0 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 4 WD40 domain HSP70 PF00012.20 CBK19787.2 - 1.5e-100 337.2 3.1 8.5e-100 334.7 3.1 1.8 1 1 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 CBK19787.2 - 4.1e-11 42.3 0.0 1.5e-10 40.4 0.0 1.9 2 1 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.16 CBK19787.2 - 0.0001 22.1 0.1 0.00045 20.0 0.0 1.9 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain FtsA PF14450.6 CBK19787.2 - 0.018 15.4 0.1 12 6.3 0.0 2.9 3 0 0 3 3 3 0 Cell division protein FtsA ABC_tran PF00005.27 CBK19788.2 - 4.9e-49 166.4 0.0 4.1e-28 98.6 0.0 2.4 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 CBK19788.2 - 1e-43 150.0 32.2 6.8e-27 94.8 14.1 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.19 CBK19788.2 - 4.3e-07 29.6 3.3 0.011 15.2 0.0 4.0 3 1 1 4 4 4 1 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 CBK19788.2 - 6.2e-05 23.1 1.0 0.33 11.1 0.1 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase Dynamin_N PF00350.23 CBK19788.2 - 6.5e-05 23.1 0.2 0.046 13.8 0.0 3.3 3 0 0 3 3 3 1 Dynamin family AAA_16 PF13191.6 CBK19788.2 - 0.00028 21.3 0.1 0.12 12.7 0.0 2.8 2 1 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.6 CBK19788.2 - 0.00043 20.0 0.1 1.3 8.8 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.6 CBK19788.2 - 0.00057 20.4 0.3 0.45 11.0 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 CBK19788.2 - 0.0023 17.5 0.8 0.014 14.9 0.1 2.2 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 CBK19788.2 - 0.0068 16.3 0.3 1.7 8.5 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase Chordopox_A13L PF05961.11 CBK19788.2 - 0.0076 16.5 2.4 0.96 9.7 0.4 3.3 2 0 0 2 2 2 1 Chordopoxvirus A13L protein AAA PF00004.29 CBK19788.2 - 0.021 15.2 0.6 1.5 9.2 0.0 3.0 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) DUF87 PF01935.17 CBK19788.2 - 0.023 14.8 5.1 1 9.4 0.3 2.4 2 0 0 2 2 2 0 Helicase HerA, central domain T2SSE PF00437.20 CBK19788.2 - 0.027 13.5 0.0 0.12 11.5 0.0 1.9 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_30 PF13604.6 CBK19788.2 - 0.027 14.2 4.1 2 8.1 0.1 3.2 4 0 0 4 4 4 0 AAA domain RNA_helicase PF00910.22 CBK19788.2 - 0.037 14.4 1.1 4.5 7.7 0.0 3.5 3 0 0 3 3 3 0 RNA helicase IstB_IS21 PF01695.17 CBK19788.2 - 0.047 13.4 2.0 24 4.6 0.1 3.7 4 0 0 4 4 4 0 IstB-like ATP binding protein AAA_7 PF12775.7 CBK19788.2 - 0.049 13.2 0.6 4.2 6.8 0.1 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_21 PF13304.6 CBK19788.2 - 0.049 13.4 0.0 11 5.7 0.0 3.0 3 0 0 3 3 3 0 AAA domain, putative AbiEii toxin, Type IV TA system DEAD PF00270.29 CBK19788.2 - 0.095 12.5 0.3 6.1 6.6 0.1 2.9 2 1 0 2 2 2 0 DEAD/DEAH box helicase KAP_NTPase PF07693.14 CBK19788.2 - 0.1 11.8 0.0 0.3 10.3 0.0 1.8 2 0 0 2 2 2 0 KAP family P-loop domain AAA_22 PF13401.6 CBK19788.2 - 0.12 12.7 2.8 7.1 6.9 0.2 3.2 2 1 0 2 2 2 0 AAA domain PRK PF00485.18 CBK19788.2 - 0.12 12.0 1.3 1.1 9.0 0.1 2.4 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family Zeta_toxin PF06414.12 CBK19788.2 - 0.15 11.3 1.5 2.3 7.4 0.1 2.4 2 0 0 2 2 2 0 Zeta toxin NACHT PF05729.12 CBK19788.2 - 0.15 12.0 0.1 0.15 12.0 0.1 2.7 3 0 0 3 3 3 0 NACHT domain ATPase PF06745.13 CBK19788.2 - 0.2 10.9 0.5 0.47 9.8 0.0 1.8 2 0 0 2 2 2 0 KaiC MeaB PF03308.16 CBK19788.2 - 0.22 10.5 1.9 4.1 6.3 0.0 2.2 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_18 PF13238.6 CBK19788.2 - 0.29 11.7 0.7 1.2 9.7 0.0 2.3 2 0 0 2 2 2 0 AAA domain IIGP PF05049.13 CBK19788.2 - 0.29 10.1 1.3 1.7 7.6 0.1 2.2 2 0 0 2 2 2 0 Interferon-inducible GTPase (IIGP) NTPase_1 PF03266.15 CBK19788.2 - 1.1 9.1 3.9 16 5.3 0.2 3.6 4 0 0 4 4 4 0 NTPase CNDH2_C PF16858.5 CBK19789.2 - 0.012 15.5 7.0 0.016 15.1 7.0 1.1 1 0 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term FAIM1 PF06905.13 CBK19789.2 - 0.015 15.0 1.0 0.021 14.5 1.0 1.2 1 0 0 1 1 1 0 Fas apoptotic inhibitory molecule (FAIM1) DUF3334 PF11813.8 CBK19789.2 - 0.037 13.7 1.6 0.053 13.3 1.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3334) BSP_II PF05432.11 CBK19789.2 - 0.054 13.2 17.5 0.081 12.6 17.5 1.3 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) DUF2052 PF09747.9 CBK19789.2 - 0.089 12.9 12.7 0.13 12.4 12.7 1.2 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) CDC45 PF02724.14 CBK19789.2 - 0.37 9.0 8.3 0.4 8.9 8.3 1.1 1 0 0 1 1 1 0 CDC45-like protein Na_trans_assoc PF06512.13 CBK19789.2 - 0.44 10.8 10.8 0.51 10.6 10.8 1.1 1 0 0 1 1 1 0 Sodium ion transport-associated Hid1 PF12722.7 CBK19789.2 - 0.64 8.1 3.1 0.7 8.0 3.1 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Nop14 PF04147.12 CBK19789.2 - 2.1 6.4 17.1 2.5 6.2 17.1 1.0 1 0 0 1 1 1 0 Nop14-like family BUD22 PF09073.10 CBK19789.2 - 2.5 7.3 15.1 3.1 7.0 15.1 1.1 1 0 0 1 1 1 0 BUD22 SDA1 PF05285.12 CBK19789.2 - 3 7.2 17.5 3.8 6.8 17.5 1.1 1 0 0 1 1 1 0 SDA1 DUF4065 PF13274.6 CBK19789.2 - 4.5 8.2 8.5 1.2 10.0 5.1 1.9 2 1 0 2 2 2 0 Protein of unknown function (DUF4065) TFIIS_M PF07500.14 CBK19790.2 - 1.6e-22 80.1 1.5 2.7e-22 79.4 1.5 1.4 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS), central domain RRM_1 PF00076.22 CBK19792.2 - 1e-05 25.3 0.0 1.5e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Pkinase PF00069.25 CBK19793.2 - 1.9e-44 152.0 0.2 4.5e-25 88.5 0.1 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CBK19793.2 - 1.9e-17 63.4 0.0 1.9e-14 53.6 0.1 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 CBK19793.2 - 0.00041 19.8 0.0 0.19 11.0 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.14 CBK19793.2 - 0.00084 18.7 0.0 0.0015 18.0 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 CBK19793.2 - 0.0063 16.1 0.4 0.01 15.4 0.4 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.23 CBK19793.2 - 0.013 15.5 0.0 0.02 14.9 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family FTA2 PF13095.6 CBK19793.2 - 0.019 14.6 0.1 0.034 13.7 0.1 1.4 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Pkinase_fungal PF17667.1 CBK19793.2 - 0.024 13.4 0.0 0.033 13.0 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase HSP70 PF00012.20 CBK19794.2 - 1.2e-75 254.9 0.0 1.5e-75 254.6 0.0 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 CBK19794.2 - 1.7e-16 60.0 0.1 7.3e-15 54.6 0.0 2.3 2 1 0 2 2 2 2 MreB/Mbl protein DDR PF08841.10 CBK19794.2 - 0.00041 19.5 0.7 0.031 13.3 0.0 2.6 3 0 0 3 3 3 2 Diol dehydratase reactivase ATPase-like domain PilM_2 PF11104.8 CBK19794.2 - 0.0031 16.6 0.0 1.9 7.4 0.0 2.2 1 1 0 2 2 2 2 Type IV pilus assembly protein PilM; 14-3-3 PF00244.20 CBK19795.2 - 1.9e-84 282.6 4.4 2.1e-84 282.5 4.4 1.0 1 0 0 1 1 1 1 14-3-3 protein TPR_21 PF09976.9 CBK19795.2 - 0.012 15.3 0.1 5.5 6.7 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat-like domain Helicase_C_2 PF13307.6 CBK19796.2 - 2.8e-52 177.3 0.1 1.5e-51 175.0 0.0 2.2 3 0 0 3 3 3 1 Helicase C-terminal domain DEAD_2 PF06733.15 CBK19796.2 - 1.7e-45 154.8 0.1 4.9e-45 153.3 0.1 1.8 2 0 0 2 2 2 1 DEAD_2 HBB PF06777.11 CBK19796.2 - 8.7e-07 28.8 0.1 3.9e-06 26.7 0.0 2.0 2 0 0 2 2 2 1 Helical and beta-bridge domain ResIII PF04851.15 CBK19796.2 - 0.0038 17.2 0.2 2.2 8.3 0.0 2.5 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit DEAD PF00270.29 CBK19796.2 - 0.03 14.1 0.0 1.2 8.9 0.0 2.4 2 0 0 2 2 2 0 DEAD/DEAH box helicase SUB1_ProdP9 PF18213.1 CBK19796.2 - 0.086 12.7 0.0 0.59 10.0 0.0 2.3 2 0 0 2 2 2 0 SUB1 protease Prodomain ProdP9 AAA_22 PF13401.6 CBK19796.2 - 0.13 12.6 0.0 31 4.8 0.0 2.6 2 0 0 2 2 2 0 AAA domain PhoH PF02562.16 CBK19796.2 - 0.15 11.5 0.2 7.1 6.0 0.0 2.3 2 0 0 2 2 2 0 PhoH-like protein zf-C2H2 PF00096.26 CBK19797.2 - 1.4e-27 94.5 68.5 9.9e-06 25.7 1.9 8.4 8 0 0 8 8 8 8 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CBK19797.2 - 3.5e-23 80.3 64.4 0.00056 20.5 0.7 8.4 8 0 0 8 8 8 8 C2H2-type zinc finger zf-H2C2_2 PF13465.6 CBK19797.2 - 3.3e-15 55.7 71.8 2.4e-05 24.6 1.3 9.1 9 1 0 9 9 9 5 Zinc-finger double domain FOXP-CC PF16159.5 CBK19797.2 - 1.5e-08 35.1 26.9 0.1 13.3 0.1 7.0 3 3 5 8 8 8 4 FOXP coiled-coil domain zf-C2H2_8 PF15909.5 CBK19797.2 - 3.8e-07 30.3 37.2 0.01 16.1 8.8 4.9 1 1 2 4 4 4 4 C2H2-type zinc ribbon PyrI_C PF02748.15 CBK19797.2 - 3.4e-05 23.7 22.6 0.03 14.2 2.5 4.4 3 1 2 5 5 5 3 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-C2H2_11 PF16622.5 CBK19797.2 - 9.9e-05 22.0 21.7 0.28 11.0 0.1 6.1 6 0 0 6 6 6 3 zinc-finger C2H2-type zf-C2H2_6 PF13912.6 CBK19797.2 - 0.0053 16.7 44.5 0.036 14.1 2.1 7.2 8 0 0 8 8 8 3 C2H2-type zinc finger zf_Hakai PF18408.1 CBK19797.2 - 0.006 16.3 14.5 0.79 9.5 0.1 5.3 5 0 0 5 5 5 2 C2H2 Hakai zinc finger domain zf-H2C2_5 PF13909.6 CBK19797.2 - 0.046 13.5 0.0 0.046 13.5 0.0 10.0 9 2 0 9 9 8 0 C2H2-type zinc-finger domain zf-C2H2_aberr PF17017.5 CBK19797.2 - 0.11 12.6 34.7 0.055 13.6 7.2 5.8 2 2 4 6 6 6 0 Aberrant zinc-finger DUF2757 PF10955.8 CBK19797.2 - 0.56 10.5 8.8 2.4 8.5 0.1 3.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2757) Ogr_Delta PF04606.12 CBK19797.2 - 0.65 10.0 18.0 1.4 9.0 0.9 4.2 3 1 1 4 4 4 0 Ogr/Delta-like zinc finger zf_C2H2_ZHX PF18387.1 CBK19797.2 - 0.68 9.6 20.2 12 5.6 0.8 5.6 5 0 0 5 5 5 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-C2H2_jaz PF12171.8 CBK19797.2 - 0.71 10.2 51.9 0.51 10.7 2.2 8.2 8 0 0 8 8 8 0 Zinc-finger double-stranded RNA-binding zf-CHCC PF10276.9 CBK19797.2 - 1.6 8.8 11.5 11 6.1 0.5 3.7 3 0 0 3 3 3 0 Zinc-finger domain zf-FCS PF06467.14 CBK19797.2 - 3.8 7.5 23.1 4.9 7.2 0.5 5.0 4 2 1 5 5 5 0 MYM-type Zinc finger with FCS sequence motif SIR2 PF02146.17 CBK19798.2 - 1.6e-32 112.9 0.0 1.7e-32 112.8 0.0 1.0 1 0 0 1 1 1 1 Sir2 family Nudix_N_2 PF14803.6 CBK19798.2 - 0.0037 17.1 1.8 0.11 12.4 0.3 2.3 2 0 0 2 2 2 1 Nudix N-terminal zf-ribbon_3 PF13248.6 CBK19798.2 - 0.0078 15.6 4.8 0.14 11.6 0.2 2.3 2 0 0 2 2 2 2 zinc-ribbon domain zf-NADH-PPase PF09297.11 CBK19798.2 - 0.02 14.5 0.2 0.02 14.5 0.2 2.2 2 1 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain zinc_ribbon_2 PF13240.6 CBK19798.2 - 0.021 14.6 3.0 0.4 10.5 0.1 2.3 2 0 0 2 2 2 0 zinc-ribbon domain DZR PF12773.7 CBK19798.2 - 0.022 14.7 1.7 0.046 13.7 1.7 1.5 1 1 0 1 1 1 0 Double zinc ribbon Zn-ribbon_8 PF09723.10 CBK19798.2 - 0.032 14.4 3.6 0.058 13.5 3.6 1.5 1 0 0 1 1 1 0 Zinc ribbon domain zinc_ribbon_9 PF14369.6 CBK19798.2 - 0.13 12.6 4.8 2.8 8.3 0.2 2.3 2 0 0 2 2 2 0 zinc-ribbon HemS PF05171.12 CBK19799.2 - 0.08 12.9 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 Haemin-degrading HemS.ChuX domain He_PIG PF05345.12 CBK19801.2 - 1.7e-10 40.9 23.5 2.6e-06 27.5 1.7 4.9 4 1 0 4 4 4 3 Putative Ig domain DUF11 PF01345.18 CBK19801.2 - 7.7e-08 32.5 0.0 0.02 15.2 0.0 3.5 2 1 1 3 3 3 2 Domain of unknown function DUF11 DUF3185 PF11381.8 CBK19801.2 - 0.011 15.7 1.2 0.051 13.6 1.2 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3185) TMEM238 PF15125.6 CBK19801.2 - 0.013 15.6 2.4 0.03 14.5 2.4 1.6 1 0 0 1 1 1 0 TMEM238 protein family Tme5_EGF_like PF09064.10 CBK19801.2 - 0.022 14.7 0.7 9.8 6.2 0.1 3.3 3 0 0 3 3 3 0 Thrombomodulin like fifth domain, EGF-like HRM PF02793.22 CBK19801.2 - 0.052 13.9 8.9 14 6.1 0.2 4.3 4 0 0 4 4 4 0 Hormone receptor domain Neurensin PF14927.6 CBK19801.2 - 0.091 12.5 1.2 0.17 11.6 1.2 1.4 1 0 0 1 1 1 0 Neurensin DUF3040 PF11239.8 CBK19801.2 - 0.15 12.4 1.2 0.33 11.3 1.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3040) DUF4245 PF14030.6 CBK19801.2 - 0.32 11.0 4.2 0.67 10.0 4.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4245) CPW_WPC PF09717.10 CBK19801.2 - 0.72 10.9 5.9 4.8 8.2 0.0 3.6 4 0 0 4 4 4 0 Plasmodium falciparum domain of unknown function (CPW_WPC) FAP PF07174.11 CBK19801.2 - 6.3 6.2 36.8 11 5.4 36.8 1.3 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) TFIIA PF03153.13 CBK19802.2 - 0.024 14.7 10.0 0.027 14.5 10.0 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Presenilin PF01080.17 CBK19802.2 - 2.2 7.0 4.5 2.6 6.7 4.5 1.1 1 0 0 1 1 1 0 Presenilin BET PF17035.5 CBK19803.2 - 4.6e-19 68.4 2.9 8.4e-19 67.5 2.9 1.5 1 0 0 1 1 1 1 Bromodomain extra-terminal - transcription regulation Bromodomain PF00439.25 CBK19803.2 - 3.9e-07 30.0 0.1 1.3e-06 28.4 0.0 2.0 2 0 0 2 2 2 1 Bromodomain GreA_GreB_N PF03449.15 CBK19803.2 - 0.074 13.2 2.4 4.1 7.6 0.5 2.6 2 0 0 2 2 2 0 Transcription elongation factor, N-terminal DASH_Dad3 PF08656.10 CBK19803.2 - 0.16 12.1 0.8 0.42 10.7 0.8 1.8 1 1 0 1 1 1 0 DASH complex subunit Dad3 Seryl_tRNA_N PF02403.22 CBK19803.2 - 0.2 11.9 6.1 0.17 12.1 2.4 2.2 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain FAM199X PF15814.5 CBK19803.2 - 2.5 7.1 7.3 0.064 12.3 0.3 1.8 1 1 0 2 2 2 0 Protein family FAM199X SPT16 PF08644.11 CBK19804.2 - 2.2e-44 151.3 0.4 2.2e-44 151.3 0.4 2.5 2 0 0 2 2 2 1 FACT complex subunit (SPT16/CDC68) Peptidase_M24 PF00557.24 CBK19804.2 - 4.6e-25 88.5 0.0 8.4e-25 87.7 0.0 1.4 1 0 0 1 1 1 1 Metallopeptidase family M24 Rtt106 PF08512.12 CBK19804.2 - 7.3e-15 55.2 0.2 2.5e-14 53.5 0.2 1.9 1 0 0 1 1 1 1 Histone chaperone Rttp106-like Fer2_4 PF13510.6 CBK19804.2 - 0.036 14.1 0.1 4.1 7.5 0.0 2.5 2 0 0 2 2 2 0 2Fe-2S iron-sulfur cluster binding domain bPH_2 PF03703.14 CBK19804.2 - 0.14 12.4 1.1 0.5 10.6 0.0 2.4 2 0 0 2 2 2 0 Bacterial PH domain Prefoldin_2 PF01920.20 CBK19805.2 - 2.6e-14 53.0 9.6 3e-14 52.8 9.6 1.1 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin PF02996.17 CBK19805.2 - 0.012 15.5 10.8 0.058 13.3 3.5 2.1 1 1 1 2 2 2 0 Prefoldin subunit DUF3450 PF11932.8 CBK19805.2 - 0.016 14.5 5.6 0.12 11.7 0.5 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) Golgin_A5 PF09787.9 CBK19805.2 - 0.068 12.6 8.9 0.09 12.2 8.9 1.1 1 0 0 1 1 1 0 Golgin subfamily A member 5 Med30 PF11315.8 CBK19805.2 - 0.07 13.3 6.9 0.52 10.5 0.8 2.1 2 0 0 2 2 2 0 Mediator complex subunit 30 AAA_11 PF13086.6 CBK19805.2 - 0.071 12.9 2.2 0.082 12.7 2.2 1.0 1 0 0 1 1 1 0 AAA domain HA2 PF04408.23 CBK19805.2 - 0.17 12.2 1.5 0.3 11.4 0.7 1.8 1 1 1 2 2 2 0 Helicase associated domain (HA2) Lipoprotein_20 PF13942.6 CBK19805.2 - 0.18 11.7 5.4 0.1 12.5 0.8 2.0 2 0 0 2 2 2 0 YfhG lipoprotein FANCI_S4 PF14678.6 CBK19805.2 - 0.22 10.6 4.3 1.2 8.2 4.3 1.9 1 1 0 1 1 1 0 FANCI solenoid 4 DASH_Dad3 PF08656.10 CBK19805.2 - 0.34 11.0 4.6 0.71 10.0 4.6 1.8 1 1 0 1 1 1 0 DASH complex subunit Dad3 DUF3671 PF12420.8 CBK19805.2 - 0.35 11.0 3.7 0.98 9.5 0.7 2.1 2 0 0 2 2 2 0 Protein of unknown function Sas10_Utp3 PF04000.15 CBK19805.2 - 0.43 11.2 5.2 4.9 7.8 0.7 2.2 2 0 0 2 2 2 0 Sas10/Utp3/C1D family DUF1043 PF06295.12 CBK19805.2 - 0.45 10.5 7.4 0.36 10.8 2.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1043) DUF5320 PF17253.2 CBK19805.2 - 0.59 11.2 5.1 11 7.2 0.9 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5320) FapA PF03961.13 CBK19805.2 - 0.63 8.6 11.7 3.3 6.2 11.7 1.8 1 1 0 1 1 1 0 Flagellar Assembly Protein A COG2 PF06148.11 CBK19805.2 - 1.5 8.9 8.3 44 4.2 8.3 2.1 1 1 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 Med21 PF11221.8 CBK19805.2 - 1.9 8.7 9.6 3.8 7.7 3.0 2.1 2 0 0 2 2 2 0 Subunit 21 of Mediator complex Dzip-like_N PF13815.6 CBK19805.2 - 2.4 8.1 8.4 1.6 8.7 1.8 2.1 2 0 0 2 2 2 0 Iguana/Dzip1-like DAZ-interacting protein N-terminal YabA PF06156.13 CBK19805.2 - 4.1 8.1 11.3 47 4.7 11.4 2.1 1 1 0 1 1 1 0 Initiation control protein YabA LMBR1 PF04791.16 CBK19805.2 - 4.6 6.0 4.4 2.9 6.7 0.5 1.7 1 1 0 1 1 1 0 LMBR1-like membrane protein Spc24 PF08286.11 CBK19805.2 - 5 7.4 15.3 5.6 7.3 1.7 2.1 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 Mannosyl_trans PF05007.13 CBK19807.2 - 1.1e-52 179.5 30.4 1.1e-52 179.5 30.4 2.2 2 1 0 2 2 2 1 Mannosyltransferase (PIG-M) GT87 PF09594.10 CBK19807.2 - 5e-09 36.2 5.7 5e-09 36.2 5.7 1.8 1 1 0 1 1 1 1 Glycosyltransferase family 87 PIG-U PF06728.13 CBK19807.2 - 1.1e-05 24.7 36.5 2.8e-05 23.4 36.5 1.6 1 1 0 1 1 1 1 GPI transamidase subunit PIG-U DUF1772 PF08592.11 CBK19807.2 - 0.1 12.9 5.8 0.96 9.8 0.4 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1772) Adap_comp_sub PF00928.21 CBK19808.2 - 2.1e-25 89.6 0.0 3e-25 89.1 0.0 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 CBK19808.2 - 0.00018 21.4 0.4 0.00031 20.7 0.4 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain DUF2076 PF09849.9 CBK19808.2 - 0.061 13.4 4.8 0.086 12.9 4.8 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) Ribosomal_L34e PF01199.18 CBK19809.2 - 5.2e-27 94.0 7.5 5.2e-27 94.0 7.5 3.0 2 1 0 2 2 2 1 Ribosomal protein L34e FYVE PF01363.21 CBK19809.2 - 0.00017 21.7 3.6 0.0003 20.9 3.6 1.5 1 1 0 1 1 1 1 FYVE zinc finger MscS_TM PF12794.7 CBK19809.2 - 0.93 8.3 3.4 0.22 10.4 0.3 1.5 2 0 0 2 2 2 0 Mechanosensitive ion channel inner membrane domain 1 NAD_kinase PF01513.21 CBK19810.2 - 9.3e-55 185.9 0.0 1.5e-54 185.2 0.0 1.2 1 0 0 1 1 1 1 ATP-NAD kinase CX9C PF16860.5 CBK19811.2 - 0.19 11.8 1.0 0.23 11.5 0.2 1.6 2 0 0 2 2 2 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, Radical_SAM PF04055.21 CBK19812.2 - 1.8e-23 83.8 0.0 3.4e-23 82.9 0.0 1.4 1 0 0 1 1 1 1 Radical SAM superfamily PTPA PF03095.15 CBK19813.2 - 1e-91 307.5 0.0 1.2e-91 307.3 0.0 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein DUF4816 PF16086.5 CBK19814.2 - 0.083 12.8 3.7 2.4 8.1 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4816) CoA_transf_3 PF02515.17 CBK19814.2 - 0.13 11.4 0.0 0.13 11.4 0.0 1.1 1 0 0 1 1 1 0 CoA-transferase family III CDI PF02234.19 CBK19814.2 - 0.23 11.7 2.9 0.92 9.7 0.0 2.2 2 0 0 2 2 2 0 Cyclin-dependent kinase inhibitor Proteasome PF00227.26 CBK19815.2 - 5.5e-40 136.9 0.0 6.3e-40 136.7 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit CS PF04969.16 CBK19816.2 - 1.4e-10 42.0 0.5 2.7e-10 41.1 0.5 1.5 1 0 0 1 1 1 1 CS domain Mt_ATP-synt_D PF05873.12 CBK19816.2 - 0.0093 15.8 2.7 0.021 14.7 0.9 2.0 1 1 1 2 2 2 1 ATP synthase D chain, mitochondrial (ATP5H) Apyrase PF06079.11 CBK19816.2 - 0.017 14.3 0.7 0.021 14.1 0.7 1.1 1 0 0 1 1 1 0 Apyrase TAP42 PF04177.12 CBK19817.2 - 8.1e-25 87.6 13.8 9.2e-25 87.4 13.8 1.0 1 0 0 1 1 1 1 TAP42-like family SF3A3 PF16837.5 CBK19817.2 - 0.1 13.1 0.2 1.5 9.4 0.2 2.2 2 0 0 2 2 2 0 Pre-mRNA-splicing factor SF3A3, of SF3a complex, Prp9 DUF1104 PF06518.11 CBK19817.2 - 0.32 11.4 8.9 0.12 12.7 5.8 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1104) Ribosomal_60s PF00428.19 CBK19818.2 - 1.4e-22 80.1 15.1 1.6e-22 79.9 15.1 1.0 1 0 0 1 1 1 1 60s Acidic ribosomal protein RNA_pol_3_Rpc31 PF11705.8 CBK19818.2 - 0.9 9.7 7.9 1.2 9.4 7.9 1.1 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 FAINT PF04385.15 CBK19819.2 - 0.005 16.9 1.6 0.0053 16.8 1.6 1.0 1 0 0 1 1 1 1 Domain of unknown function, DUF529 Bombinin PF05298.11 CBK19820.2 - 0.00066 19.4 0.2 0.0012 18.5 0.0 1.5 1 1 0 1 1 1 1 Bombinin IFT43 PF15305.6 CBK19820.2 - 0.00074 19.7 0.1 0.001 19.3 0.1 1.2 1 0 0 1 1 1 1 Intraflagellar transport protein 43 Methyltransf_8 PF05148.15 CBK19822.2 - 4e-63 213.2 0.1 5.8e-63 212.7 0.1 1.1 1 0 0 1 1 1 1 Hypothetical methyltransferase Methyltransf_11 PF08241.12 CBK19822.2 - 2.2e-05 25.0 0.1 0.00032 21.3 0.0 2.5 2 1 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 CBK19822.2 - 0.00057 19.5 0.0 0.062 12.9 0.0 2.3 1 1 1 2 2 2 2 Methyltransferase small domain Methyltransf_25 PF13649.6 CBK19822.2 - 0.0042 17.8 0.1 2 9.1 0.0 3.1 2 1 0 2 2 2 1 Methyltransferase domain Ribosomal_L5_C PF00673.21 CBK19823.2 - 1.5e-20 73.1 0.0 2.4e-20 72.5 0.0 1.3 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.19 CBK19823.2 - 1.9e-18 66.5 0.3 3.8e-18 65.6 0.1 1.6 2 0 0 2 2 2 1 Ribosomal protein L5 HTH_ABP1_N PF18107.1 CBK19823.2 - 0.013 15.2 0.4 0.071 12.8 0.1 2.0 2 0 0 2 2 2 0 Fission yeast centromere protein N-terminal domain Dyp_perox PF04261.12 CBK19824.2 - 3.4e-59 200.5 0.0 3.7e-59 200.4 0.0 1.1 1 0 0 1 1 1 1 Dyp-type peroxidase family GTP_EFTU PF00009.27 CBK19825.2 - 3.9e-33 114.6 0.2 2e-32 112.3 0.0 2.3 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain IF-2 PF11987.8 CBK19825.2 - 2.1e-19 69.6 0.0 5.9e-19 68.2 0.0 1.8 1 0 0 1 1 1 1 Translation-initiation factor 2 GTP_EFTU_D4 PF14578.6 CBK19825.2 - 7e-14 51.5 0.9 1.4e-08 34.5 0.3 2.8 2 0 0 2 2 2 2 Elongation factor Tu domain 4 GTP_EFTU_D2 PF03144.25 CBK19825.2 - 6.5e-11 42.5 14.4 2.7e-10 40.5 0.1 4.4 5 0 0 5 5 5 2 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 CBK19825.2 - 2.2e-08 34.2 0.2 3.9e-07 30.1 0.0 3.2 3 0 0 3 3 3 1 50S ribosome-binding GTPase ATP_bind_1 PF03029.17 CBK19825.2 - 4.4e-05 23.4 0.0 0.00019 21.3 0.0 2.2 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein Roc PF08477.13 CBK19825.2 - 0.00049 20.3 0.0 0.0011 19.1 0.0 1.6 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase RsgA_GTPase PF03193.16 CBK19825.2 - 0.00059 19.8 0.2 0.014 15.3 0.1 2.6 1 1 1 2 2 2 1 RsgA GTPase Ras PF00071.22 CBK19825.2 - 0.003 17.2 0.0 0.016 14.8 0.0 2.2 1 1 0 1 1 1 1 Ras family AAA_22 PF13401.6 CBK19825.2 - 0.096 13.0 0.1 0.096 13.0 0.1 2.6 3 1 0 3 3 3 0 AAA domain SRPRB PF09439.10 CBK19825.2 - 0.1 12.0 0.1 0.1 12.0 0.1 2.7 2 1 0 2 2 1 0 Signal recognition particle receptor beta subunit AAA_16 PF13191.6 CBK19825.2 - 0.51 10.7 0.0 0.51 10.7 0.0 4.2 4 1 1 5 5 5 0 AAA ATPase domain Fer2_3 PF13085.6 CBK19826.2 - 1.5e-33 115.0 0.1 2.6e-33 114.3 0.1 1.4 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer4_8 PF13183.6 CBK19826.2 - 1.7e-08 34.8 7.3 1.7e-08 34.8 7.3 2.3 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_17 PF13534.6 CBK19826.2 - 1.9e-08 34.7 6.5 1.9e-08 34.7 6.5 2.0 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_10 PF13237.6 CBK19826.2 - 2.5e-07 30.7 3.4 2.5e-07 30.7 3.4 2.1 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer2 PF00111.27 CBK19826.2 - 0.00012 21.9 0.4 0.00012 21.9 0.4 2.0 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fer4_7 PF12838.7 CBK19826.2 - 0.003 18.1 4.8 0.003 18.1 4.8 2.7 2 2 0 2 2 2 1 4Fe-4S dicluster domain Fer4_9 PF13187.6 CBK19826.2 - 0.028 14.6 7.9 0.028 14.6 7.9 2.5 2 1 0 2 2 2 0 4Fe-4S dicluster domain Herpes_UL51 PF04540.13 CBK19826.2 - 0.12 12.1 0.0 0.2 11.4 0.0 1.3 1 0 0 1 1 1 0 Herpesvirus UL51 protein Fer4_13 PF13370.6 CBK19826.2 - 0.96 10.0 6.2 10 6.8 0.4 3.4 3 0 0 3 3 3 0 4Fe-4S single cluster domain of Ferredoxin I Got1 PF04178.12 CBK19827.2 - 7.7e-05 23.1 9.2 7.7e-05 23.1 9.2 2.0 1 1 1 2 2 2 1 Got1/Sft2-like family Peptidase_A24 PF01478.18 CBK19827.2 - 1.1 9.7 5.5 1.9 9.0 0.5 2.2 1 1 1 2 2 2 0 Type IV leader peptidase family TRAP_alpha PF03896.16 CBK19829.2 - 4.7e-10 39.1 5.7 5.4e-10 38.9 5.7 1.1 1 0 0 1 1 1 1 Translocon-associated protein (TRAP), alpha subunit Ribosomal_S5_C PF03719.15 CBK19830.2 - 7.1e-26 89.5 0.0 1.2e-25 88.8 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain Ribosomal_S5 PF00333.20 CBK19830.2 - 3.5e-25 87.8 2.1 6.9e-25 86.8 2.1 1.5 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain PRR20 PF15708.5 CBK19830.2 - 0.018 15.0 2.5 0.025 14.5 1.1 1.8 2 0 0 2 2 2 0 Proline-rich protein family 20 dCMP_cyt_deam_1 PF00383.23 CBK19831.2 - 4.8e-18 64.9 0.1 6.2e-16 58.1 0.1 2.3 1 1 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 CBK19831.2 - 2e-14 53.5 0.0 2.2e-12 46.9 0.0 2.1 1 1 0 1 1 1 1 MafB19-like deaminase Bd3614-deam PF14439.6 CBK19831.2 - 3.7e-06 27.1 0.5 0.00016 21.8 0.5 2.2 1 1 0 1 1 1 1 Bd3614-like deaminase APOBEC2 PF18772.1 CBK19831.2 - 0.00086 19.4 0.0 0.0017 18.5 0.0 1.4 2 0 0 2 2 2 1 APOBEC2 SNAD4 PF18750.1 CBK19831.2 - 0.001 19.1 0.1 0.0024 18.0 0.0 1.6 2 0 0 2 2 2 1 Secreted Novel AID/APOBEC-like Deaminase 4 NAD1 PF18778.1 CBK19831.2 - 0.0015 18.6 0.1 0.0029 17.7 0.0 1.5 2 0 0 2 2 2 1 Novel AID APOBEC clade 1 APOBEC3 PF18771.1 CBK19831.2 - 0.0025 18.0 0.2 0.013 15.6 0.0 1.9 2 0 0 2 2 2 1 APOBEC3 NAD2 PF18782.1 CBK19831.2 - 0.022 14.9 0.0 0.04 14.0 0.0 1.4 1 0 0 1 1 1 0 Novel AID APOBEC clade 2 Dus PF01207.17 CBK19832.2 - 5.5e-48 163.6 0.0 7.3e-31 107.4 0.0 2.3 2 1 0 2 2 2 2 Dihydrouridine synthase (Dus) DUF4349 PF14257.6 CBK19833.2 - 0.0022 17.5 5.2 0.003 17.0 5.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4349) EMP24_GP25L PF01105.24 CBK19833.2 - 0.0042 17.0 8.0 0.023 14.7 8.0 1.8 1 1 0 1 1 1 1 emp24/gp25L/p24 family/GOLD GOLD_2 PF13897.6 CBK19833.2 - 0.0046 17.5 1.9 0.0096 16.4 0.0 2.0 2 0 0 2 2 2 1 Golgi-dynamics membrane-trafficking AAA_23 PF13476.6 CBK19833.2 - 0.018 15.6 5.1 0.02 15.4 5.1 1.1 1 0 0 1 1 1 0 AAA domain DUF4107 PF13389.6 CBK19833.2 - 0.046 13.9 0.2 0.06 13.5 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4107) TMPIT PF07851.13 CBK19833.2 - 0.23 10.7 9.7 0.29 10.3 9.7 1.1 1 0 0 1 1 1 0 TMPIT-like protein Atg14 PF10186.9 CBK19833.2 - 0.52 9.3 10.1 0.67 9.0 10.1 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 GvpG PF05120.12 CBK19833.2 - 0.53 10.3 8.1 0.89 9.6 8.1 1.3 1 0 0 1 1 1 0 Gas vesicle protein G DUF4201 PF13870.6 CBK19833.2 - 0.56 9.9 17.8 0.26 11.0 14.2 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) UPF0242 PF06785.11 CBK19833.2 - 1.4 9.0 14.7 0.6 10.2 1.6 2.1 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus DUF16 PF01519.16 CBK19833.2 - 3.4 8.2 13.4 4.7 7.8 5.8 2.1 1 1 1 2 2 2 0 Protein of unknown function DUF16 TEX13 PF15186.6 CBK19833.2 - 7.1 6.3 12.2 11 5.6 12.2 1.3 1 1 0 1 1 1 0 Testis-expressed sequence 13 protein family Aminotran_1_2 PF00155.21 CBK19835.2 - 1.4e-37 129.8 0.0 1.8e-37 129.4 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 CBK19835.2 - 0.017 14.4 0.0 0.041 13.2 0.0 1.7 2 0 0 2 2 2 0 Beta-eliminating lyase Topoisom_I PF01028.20 CBK19836.2 - 0.071 12.3 0.0 0.12 11.6 0.0 1.3 1 0 0 1 1 1 0 Eukaryotic DNA topoisomerase I, catalytic core Helicase_IV_N PF12462.8 CBK19836.2 - 0.14 12.1 0.0 0.16 11.9 0.0 1.2 1 1 0 1 1 1 0 DNA helicase IV / RNA helicase N terminal TPR_1 PF00515.28 CBK19837.2 - 4.2e-14 51.7 12.5 5.8e-05 22.7 0.1 5.7 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_2 PF07719.17 CBK19837.2 - 2.1e-13 49.3 12.7 0.00094 19.1 0.1 5.7 5 1 1 6 6 5 4 Tetratricopeptide repeat TPR_8 PF13181.6 CBK19837.2 - 4.4e-09 35.8 10.9 0.0042 17.2 0.2 6.0 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_12 PF13424.6 CBK19837.2 - 1.1e-07 32.1 5.0 0.0054 17.0 0.9 4.2 3 2 2 5 5 5 4 Tetratricopeptide repeat TPR_16 PF13432.6 CBK19837.2 - 4.8e-07 30.3 1.4 0.0028 18.2 0.8 3.5 2 1 0 3 3 3 1 Tetratricopeptide repeat ANAPC3 PF12895.7 CBK19837.2 - 6.4e-06 26.3 5.0 0.0012 19.0 1.3 3.5 3 0 0 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.6 CBK19837.2 - 2.7e-05 23.9 0.4 0.36 10.9 0.0 4.3 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_9 PF13371.6 CBK19837.2 - 9e-05 22.5 0.3 0.76 10.0 0.4 3.3 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_10 PF13374.6 CBK19837.2 - 0.0011 18.8 0.5 2.1 8.3 0.6 3.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.6 CBK19837.2 - 0.0034 18.1 0.6 63 4.8 0.0 4.7 3 2 2 5 5 5 0 Tetratricopeptide repeat TPR_19 PF14559.6 CBK19837.2 - 0.0067 16.9 4.8 1.4 9.5 0.0 3.6 4 0 0 4 4 4 2 Tetratricopeptide repeat SPO22 PF08631.10 CBK19837.2 - 0.037 13.5 1.0 0.64 9.4 0.1 2.5 2 1 1 3 3 3 0 Meiosis protein SPO22/ZIP4 like PknG_TPR PF16918.5 CBK19837.2 - 0.043 12.5 0.0 2 7.1 0.0 2.2 1 1 1 2 2 2 0 Protein kinase G tetratricopeptide repeat TPR_11 PF13414.6 CBK19837.2 - 0.043 13.5 1.1 0.043 13.5 1.1 3.3 4 1 1 5 5 5 0 TPR repeat TPR_3 PF07720.12 CBK19837.2 - 0.12 12.4 0.2 0.12 12.4 0.2 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_17 PF13431.6 CBK19837.2 - 0.2 12.1 2.2 4.1 8.0 0.0 3.5 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.6 CBK19837.2 - 1.7 9.4 7.6 81 4.2 0.0 5.1 5 0 0 5 5 5 0 Tetratricopeptide repeat adh_short PF00106.25 CBK19839.2 - 4.2e-53 179.7 2.8 5.4e-53 179.4 2.8 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CBK19839.2 - 1.1e-40 139.7 0.2 1.3e-40 139.4 0.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CBK19839.2 - 2.8e-14 53.4 0.5 4e-14 52.9 0.5 1.1 1 0 0 1 1 1 1 KR domain THF_DHG_CYH_C PF02882.19 CBK19839.2 - 0.0019 17.6 0.3 0.0047 16.3 0.3 1.7 1 1 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Ldh_1_N PF00056.23 CBK19839.2 - 0.0019 18.3 0.4 0.0019 18.3 0.4 2.0 2 1 0 2 2 2 1 lactate/malate dehydrogenase, NAD binding domain Polysacc_synt_2 PF02719.15 CBK19839.2 - 0.0047 16.1 0.1 0.0074 15.4 0.1 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein GDP_Man_Dehyd PF16363.5 CBK19839.2 - 0.005 16.3 0.1 0.0075 15.7 0.1 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 CBK19839.2 - 0.0065 15.9 0.2 0.012 15.1 0.1 1.5 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Ubie_methyltran PF01209.18 CBK19839.2 - 0.011 15.0 0.2 0.025 13.9 0.1 1.6 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family Ribosomal_S6e PF01092.19 CBK19840.2 - 1e-56 190.3 0.0 1e-56 190.3 0.0 1.5 2 0 0 2 2 2 1 Ribosomal protein S6e Nicastrin PF05450.15 CBK19841.2 - 5.2e-11 42.5 0.0 1.1e-09 38.2 0.0 2.2 1 1 0 1 1 1 1 Nicastrin Peptidase_M28 PF04389.17 CBK19841.2 - 0.00015 21.6 0.0 0.00025 20.8 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 Not3 PF04065.15 CBK19842.2 - 2.8e-18 66.2 5.2 4.3e-18 65.6 5.2 1.2 1 0 0 1 1 1 1 Not1 N-terminal domain, CCR4-Not complex component NOT2_3_5 PF04153.18 CBK19842.2 - 1.3e-09 38.2 0.3 4.9e-09 36.4 0.0 2.2 2 0 0 2 2 2 1 NOT2 / NOT3 / NOT5 family RD3 PF14473.6 CBK19842.2 - 0.013 15.3 1.0 0.03 14.2 1.0 1.6 1 0 0 1 1 1 0 RD3 protein V_ATPase_I PF01496.19 CBK19842.2 - 0.056 11.4 0.3 0.074 11.0 0.3 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family EMP70 PF02990.16 CBK19843.2 - 6.5e-134 447.4 20.3 6.5e-134 447.4 20.3 1.6 2 0 0 2 2 2 1 Endomembrane protein 70 LPP PF04728.13 CBK19844.2 - 0.0031 17.9 0.2 0.0048 17.2 0.2 1.3 1 0 0 1 1 1 1 Lipoprotein leucine-zipper CSN5_C PF18323.1 CBK19844.2 - 0.027 15.4 0.8 0.029 15.3 0.8 1.1 1 0 0 1 1 1 0 Cop9 signalosome subunit 5 C-terminal domain DLP_helical PF18709.1 CBK19844.2 - 0.045 13.0 2.8 0.044 13.0 2.8 1.0 1 0 0 1 1 1 0 Dynamin-like helical domain Atg14 PF10186.9 CBK19844.2 - 0.15 11.1 2.0 0.15 11.1 2.0 1.0 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 PIEZO PF15917.5 CBK19844.2 - 0.27 10.7 4.8 0.26 10.7 4.8 1.0 1 0 0 1 1 1 0 Piezo LMBR1 PF04791.16 CBK19844.2 - 1.1 8.1 2.5 1 8.2 2.5 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein BPL_N PF09825.9 CBK19846.2 - 2.4e-52 178.3 0.1 2.7e-52 178.1 0.1 1.0 1 0 0 1 1 1 1 Biotin-protein ligase, N terminal GATase_3 PF07685.14 CBK19846.2 - 0.00023 20.8 0.0 0.00032 20.3 0.0 1.1 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain DJ-1_PfpI PF01965.24 CBK19846.2 - 0.029 14.2 0.0 0.044 13.6 0.0 1.2 1 0 0 1 1 1 0 DJ-1/PfpI family P66_CC PF16563.5 CBK19846.2 - 0.15 11.7 0.1 0.23 11.1 0.1 1.2 1 0 0 1 1 1 0 Coiled-coil and interaction region of P66A and P66B with MBD2 HrpB7 PF09486.10 CBK19847.2 - 0.0033 17.8 7.3 0.0033 17.8 7.3 4.6 1 1 2 4 4 4 1 Bacterial type III secretion protein (HrpB7) DUF327 PF03885.13 CBK19847.2 - 0.0093 15.9 10.7 0.0093 15.9 10.7 3.7 1 1 2 3 3 3 1 Protein of unknown function (DUF327) HsbA PF12296.8 CBK19847.2 - 0.095 13.1 3.8 1 9.8 0.1 2.9 3 0 0 3 3 3 0 Hydrophobic surface binding protein A Fez1 PF06818.15 CBK19847.2 - 1.2 9.6 55.0 4.4 7.7 16.6 3.2 1 1 1 2 2 2 0 Fez1 Golgin_A5 PF09787.9 CBK19847.2 - 1.2 8.5 65.7 0.7 9.3 20.8 3.1 1 1 2 3 3 3 0 Golgin subfamily A member 5 Tropomyosin_1 PF12718.7 CBK19847.2 - 1.4 9.0 65.7 0.33 11.1 28.3 3.7 2 1 2 4 4 4 0 Tropomyosin like ERM PF00769.19 CBK19847.2 - 2.9 7.6 61.2 1.3 8.7 34.2 2.6 1 1 1 2 2 2 0 Ezrin/radixin/moesin family PDDEXK_1 PF12705.7 CBK19848.2 - 2e-06 27.9 0.1 0.0002 21.4 0.1 2.0 1 1 1 2 2 2 2 PD-(D/E)XK nuclease superfamily CitMHS PF03600.16 CBK19849.2 - 1.1e-48 166.0 34.2 1.1e-48 166.0 34.2 2.4 2 1 1 3 3 3 1 Citrate transporter Na_sulph_symp PF00939.19 CBK19849.2 - 1.2e-12 47.6 39.2 3.6e-07 29.6 17.4 3.0 1 1 1 2 2 2 2 Sodium:sulfate symporter transmembrane region ArsB PF02040.15 CBK19849.2 - 4.1e-11 42.9 28.9 6.1e-11 42.3 28.9 1.1 1 0 0 1 1 1 1 Arsenical pump membrane protein Sdh5 PF03937.16 CBK19849.2 - 0.17 11.9 0.3 0.56 10.2 0.1 1.9 2 0 0 2 2 2 0 Flavinator of succinate dehydrogenase Orf78 PF06024.12 CBK19849.2 - 6.5 7.1 5.6 17 5.7 0.0 3.7 4 0 0 4 4 4 0 Orf78 (ac78) Mur_ligase_M PF08245.12 CBK19851.2 - 2.1e-10 40.9 0.1 3e-10 40.4 0.1 1.4 1 0 0 1 1 1 1 Mur ligase middle domain zf-RING_2 PF13639.6 CBK19852.2 - 2.6e-08 34.1 1.2 4.2e-08 33.4 1.2 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 CBK19852.2 - 9.7e-07 28.7 1.8 1.6e-06 27.9 1.8 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_11 PF17123.5 CBK19852.2 - 8.7e-05 22.2 4.3 0.00017 21.3 1.8 2.3 2 0 0 2 2 2 1 RING-like zinc finger zf-rbx1 PF12678.7 CBK19852.2 - 0.00015 22.0 0.8 0.00035 20.8 0.8 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 CBK19852.2 - 0.00063 19.6 1.1 0.0012 18.7 1.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 CBK19852.2 - 0.00097 18.9 3.7 0.0035 17.1 3.7 1.9 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 CBK19852.2 - 0.002 17.9 0.6 0.0035 17.2 0.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CBK19852.2 - 0.0036 17.3 2.6 0.01 15.8 0.2 2.4 2 0 0 2 2 2 1 RING-type zinc-finger Prok-RING_1 PF14446.6 CBK19852.2 - 0.01 15.8 2.3 0.023 14.6 0.1 2.2 1 1 1 2 2 2 0 Prokaryotic RING finger family 1 PHD PF00628.29 CBK19852.2 - 0.021 14.7 0.9 0.052 13.4 0.9 1.7 1 1 1 2 2 2 0 PHD-finger Prok-RING_4 PF14447.6 CBK19852.2 - 0.026 14.4 1.3 0.055 13.3 1.3 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf_CopZ PF18423.1 CBK19852.2 - 0.042 13.8 0.2 0.11 12.5 0.1 1.8 2 0 0 2 2 1 0 Zinc binding domain zf-ANAPC11 PF12861.7 CBK19852.2 - 0.043 13.9 0.1 0.082 13.0 0.1 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3H2C3 PF17122.5 CBK19852.2 - 0.87 9.7 5.1 0.47 10.5 0.5 2.2 2 0 0 2 2 2 0 Zinc-finger CTU2 PF10288.9 CBK19852.2 - 6.3 7.1 6.0 47 4.3 6.0 2.4 1 1 0 1 1 1 0 Cytoplasmic tRNA 2-thiolation protein 2 CDC45 PF02724.14 CBK19852.2 - 8.6 4.5 7.6 12 4.0 7.6 1.1 1 0 0 1 1 1 0 CDC45-like protein UPF0113_N PF17833.1 CBK19853.2 - 3.3e-30 104.5 0.2 5e-30 103.9 0.2 1.3 1 0 0 1 1 1 1 UPF0113 Pre-PUA domain UPF0113 PF03657.13 CBK19853.2 - 1.8e-24 85.8 0.0 4.5e-24 84.5 0.0 1.6 2 0 0 2 2 2 1 UPF0113 PUA domain PP1 PF07430.11 CBK19853.2 - 0.001 19.1 0.0 0.0022 18.0 0.0 1.5 1 0 0 1 1 1 1 Phloem filament protein PP1 cystatin-like domain PUA PF01472.20 CBK19853.2 - 0.1 12.6 0.0 0.17 11.8 0.0 1.3 1 0 0 1 1 1 0 PUA domain SNase PF00565.17 CBK19854.2 - 0.00036 21.0 0.0 0.00045 20.7 0.0 1.1 1 0 0 1 1 1 1 Staphylococcal nuclease homologue TUDOR PF00567.24 CBK19854.2 - 0.1 12.6 0.0 1.3 9.1 0.0 2.3 3 0 0 3 3 3 0 Tudor domain Ras PF00071.22 CBK19855.2 - 1.4e-52 177.6 0.0 1.7e-52 177.3 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CBK19855.2 - 1.9e-30 105.5 0.0 3.7e-30 104.6 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CBK19855.2 - 3.4e-13 49.4 0.0 3.8e-13 49.2 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 CBK19855.2 - 2.8e-05 23.6 0.0 3.5e-05 23.3 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 CBK19855.2 - 6.1e-05 22.6 0.0 0.00059 19.4 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 CBK19855.2 - 0.00067 19.7 0.0 0.0013 18.8 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 CBK19855.2 - 0.0027 18.1 0.0 0.0047 17.3 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain TniB PF05621.11 CBK19855.2 - 0.016 14.7 0.0 0.03 13.7 0.0 1.5 1 0 0 1 1 1 0 Bacterial TniB protein RsgA_GTPase PF03193.16 CBK19855.2 - 0.032 14.1 0.1 2.7 7.9 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase PduV-EutP PF10662.9 CBK19855.2 - 0.054 13.2 0.0 2.9 7.6 0.0 2.1 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_7 PF12775.7 CBK19855.2 - 0.071 12.6 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region MMR_HSR1_Xtn PF16897.5 CBK19855.2 - 0.071 13.1 0.0 0.14 12.2 0.0 1.6 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain G-alpha PF00503.20 CBK19855.2 - 0.076 12.2 0.6 0.15 11.2 0.6 1.9 1 1 0 1 1 1 0 G-protein alpha subunit ATP_bind_1 PF03029.17 CBK19855.2 - 0.08 12.7 0.1 0.19 11.5 0.0 1.6 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein DEAD PF00270.29 CBK19856.2 - 1.5e-31 109.5 0.0 2.6e-31 108.7 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CBK19856.2 - 2.7e-26 92.1 0.0 9.9e-26 90.3 0.0 2.1 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Phage_terminase PF10668.9 CBK19856.2 - 0.024 14.6 0.2 0.11 12.6 0.0 2.1 2 0 0 2 2 2 0 Phage terminase small subunit ELMO_CED12 PF04727.13 CBK19857.2 - 1.1e-33 116.8 0.3 2.4e-33 115.7 0.0 1.6 2 0 0 2 2 2 1 ELMO/CED-12 family Glyco_transf_20 PF00982.21 CBK19858.2 - 1.4e-79 268.0 0.0 1.8e-79 267.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.16 CBK19858.2 - 2.4e-45 154.5 0.1 7.4e-45 152.9 0.1 1.8 1 1 0 1 1 1 1 Trehalose-phosphatase Coatomer_WDAD PF04053.14 CBK19859.2 - 4.4e-111 372.1 0.1 2.8e-109 366.1 0.0 2.1 2 0 0 2 2 2 2 Coatomer WD associated region WD40 PF00400.32 CBK19859.2 - 3.7e-37 125.7 11.6 8.9e-08 32.7 0.0 7.6 8 0 0 8 8 8 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBK19859.2 - 2e-11 44.0 0.4 0.043 14.1 0.0 6.1 5 1 2 7 7 7 5 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 CBK19859.2 - 0.00011 21.1 1.1 0.47 9.0 0.0 3.7 3 1 1 4 4 4 2 Nucleoporin Nup120/160 BBS2_Mid PF14783.6 CBK19859.2 - 0.0012 18.9 0.0 1.3 9.1 0.0 3.8 2 2 0 2 2 2 1 Ciliary BBSome complex subunit 2, middle region Frtz PF11768.8 CBK19859.2 - 0.011 14.1 0.0 0.54 8.5 0.0 2.8 3 0 0 3 3 3 0 WD repeat-containing and planar cell polarity effector protein Fritz Acyltransferase PF01553.21 CBK19860.2 - 2.5e-07 30.4 0.0 3.6e-06 26.6 0.0 2.4 1 1 0 1 1 1 1 Acyltransferase DIX PF00778.17 CBK19860.2 - 0.0002 21.1 0.0 0.00058 19.7 0.0 1.8 1 0 0 1 1 1 1 DIX domain SDA1 PF05285.12 CBK19860.2 - 0.083 12.3 9.2 0.13 11.7 9.2 1.1 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 CBK19860.2 - 0.26 9.5 12.0 0.37 8.9 12.0 1.1 1 0 0 1 1 1 0 Nop14-like family Spc7_N PF15402.6 CBK19860.2 - 0.27 9.4 11.5 0.39 8.9 11.5 1.1 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 DUF908 PF06012.12 CBK19860.2 - 1.3 8.4 8.8 1.7 8.0 8.0 1.6 2 0 0 2 2 2 0 Domain of Unknown Function (DUF908) DUF1387 PF07139.11 CBK19860.2 - 3.5 7.3 10.1 5.7 6.6 10.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) BUD22 PF09073.10 CBK19860.2 - 3.7 6.8 17.5 5.7 6.2 17.5 1.2 1 0 0 1 1 1 0 BUD22 CDC45 PF02724.14 CBK19860.2 - 3.7 5.7 8.7 5.6 5.1 8.7 1.1 1 0 0 1 1 1 0 CDC45-like protein MDFI PF15316.6 CBK19860.2 - 8.6 6.4 7.5 16 5.5 7.5 1.3 1 0 0 1 1 1 0 MyoD family inhibitor DnaJ PF00226.31 CBK19861.2 - 1.6e-07 31.3 1.5 1.7e-07 31.3 0.1 1.7 2 0 0 2 2 2 1 DnaJ domain PC4 PF02229.16 CBK19862.2 - 1.3e-18 66.3 0.0 2.3e-18 65.5 0.0 1.4 1 0 0 1 1 1 1 Transcriptional Coactivator p15 (PC4) Ribosomal_L34e PF01199.18 CBK19863.2 - 5.2e-27 94.0 7.5 5.2e-27 94.0 7.5 3.0 2 1 0 2 2 2 1 Ribosomal protein L34e FYVE PF01363.21 CBK19863.2 - 0.00017 21.7 3.6 0.0003 20.9 3.6 1.5 1 1 0 1 1 1 1 FYVE zinc finger MscS_TM PF12794.7 CBK19863.2 - 0.93 8.3 3.4 0.22 10.4 0.3 1.5 2 0 0 2 2 2 0 Mechanosensitive ion channel inner membrane domain 1 Clat_adaptor_s PF01217.20 CBK19864.2 - 0.0002 21.3 0.4 0.00033 20.6 0.4 1.2 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Adap_comp_sub PF00928.21 CBK19864.2 - 0.032 13.6 0.0 0.054 12.8 0.0 1.3 1 0 0 1 1 1 0 Adaptor complexes medium subunit family Phage_Mu_Gam PF07352.12 CBK19866.2 - 0.00011 22.1 2.4 0.00016 21.6 2.4 1.2 1 0 0 1 1 1 1 Bacteriophage Mu Gam like protein GCP_C_terminal PF04130.13 CBK19866.2 - 0.0027 17.2 0.4 0.0031 17.0 0.4 1.2 1 0 0 1 1 1 1 Gamma tubulin complex component C-terminal OmpH PF03938.14 CBK19866.2 - 0.0049 17.2 1.4 0.0062 16.9 1.4 1.2 1 0 0 1 1 1 1 Outer membrane protein (OmpH-like) DUF5446 PF17522.2 CBK19866.2 - 0.0085 16.2 0.4 0.017 15.3 0.4 1.6 1 0 0 1 1 1 1 Family of unknown function (DUF5446) Phasin PF05597.11 CBK19866.2 - 0.0089 16.0 1.3 0.014 15.4 1.3 1.3 1 0 0 1 1 1 1 Poly(hydroxyalcanoate) granule associated protein (phasin) Sds3 PF08598.11 CBK19866.2 - 0.01 15.8 1.4 0.014 15.4 1.4 1.2 1 0 0 1 1 1 0 Sds3-like Mt_ATP-synt_D PF05873.12 CBK19866.2 - 0.014 15.3 1.4 0.019 14.8 1.4 1.2 1 0 0 1 1 1 0 ATP synthase D chain, mitochondrial (ATP5H) Cnl2_NKP2 PF09447.10 CBK19866.2 - 0.062 13.5 0.3 0.14 12.3 0.3 1.6 1 0 0 1 1 1 0 Cnl2/NKP2 family protein Gln-synt_N PF03951.19 CBK19866.2 - 0.079 12.7 0.0 0.16 11.7 0.0 1.7 1 0 0 1 1 1 0 Glutamine synthetase, beta-Grasp domain DUF4337 PF14235.6 CBK19866.2 - 0.087 12.9 2.1 0.12 12.4 2.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) TMPIT PF07851.13 CBK19866.2 - 0.13 11.5 3.2 0.15 11.2 3.2 1.1 1 0 0 1 1 1 0 TMPIT-like protein DUF853 PF05872.12 CBK19866.2 - 0.15 10.7 0.3 0.17 10.5 0.3 1.0 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) DUF883 PF05957.13 CBK19866.2 - 0.21 12.2 1.8 0.43 11.2 1.8 1.5 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF883) THOC7 PF05615.13 CBK19866.2 - 0.49 10.7 7.1 1.2 9.5 7.2 1.6 1 1 0 1 1 1 0 Tho complex subunit 7 Peptidase_C97 PF05903.14 CBK19868.2 - 5.1e-32 110.8 0.0 7.3e-32 110.3 0.0 1.1 1 0 0 1 1 1 1 PPPDE putative peptidase domain TFIIS_C PF01096.18 CBK19869.2 - 3.9e-19 68.2 6.6 6.8e-19 67.4 6.6 1.4 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS) TFIIS_M PF07500.14 CBK19869.2 - 5.9e-15 55.7 0.1 1e-14 55.0 0.1 1.4 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS), central domain UPF0167 PF03691.14 CBK19869.2 - 0.054 13.3 1.6 0.11 12.3 0.9 1.8 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0167) Zn_Tnp_IS1595 PF12760.7 CBK19869.2 - 0.15 12.0 2.6 0.19 11.7 1.1 2.0 2 0 0 2 2 2 0 Transposase zinc-ribbon domain TPR_1 PF00515.28 CBK19869.2 - 0.32 10.9 1.4 0.67 9.9 1.4 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat Baculo_LEF5_C PF11792.8 CBK19869.2 - 0.4 10.4 2.3 1.6 8.4 2.3 1.9 1 1 0 1 1 1 0 Baculoviridae late expression factor 5 C-terminal domain Acetyltransf_1 PF00583.25 CBK19870.2 - 3.8e-15 56.1 0.0 5.2e-15 55.7 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 CBK19870.2 - 2.6e-10 40.6 0.0 4.1e-10 40.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 CBK19870.2 - 1.2e-08 35.0 0.0 1.5e-08 34.6 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 CBK19870.2 - 1.6e-07 31.2 0.0 2.4e-07 30.6 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 CBK19870.2 - 3.2e-05 24.0 0.1 0.00013 22.1 0.0 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_15 PF17013.5 CBK19870.2 - 6.2e-05 22.6 0.4 6.5e-05 22.5 0.4 1.3 1 0 0 1 1 1 1 Putative acetyl-transferase SMC_N PF02463.19 CBK19871.2 - 1.9e-14 53.6 8.7 3.9e-08 33.0 9.1 3.1 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 CBK19871.2 - 1e-11 45.2 0.0 4.9e-11 43.0 0.0 2.3 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 CBK19871.2 - 0.029 14.2 1.6 0.085 12.7 0.0 2.4 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system DUF3993 PF13158.6 CBK19871.2 - 0.23 11.7 3.1 0.47 10.7 0.7 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3993) UPF0167 PF03691.14 CBK19871.2 - 1.1 9.1 6.0 0.52 10.1 0.0 3.2 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0167) tRNA-synt_2b PF00587.25 CBK19872.2 - 1.5e-33 116.2 0.0 8.1e-33 113.9 0.0 2.1 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 CBK19872.2 - 1.1e-15 57.5 0.0 3.5e-15 55.9 0.0 1.9 1 0 0 1 1 1 1 Anticodon binding domain Holin_2-3 PF13272.6 CBK19872.2 - 0.18 12.1 0.0 0.36 11.2 0.0 1.4 1 0 0 1 1 1 0 Putative 2/3 transmembrane domain holin Abhydrolase_2 PF02230.16 CBK19873.2 - 5.1e-33 114.7 0.0 6.5e-33 114.4 0.0 1.1 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_3 PF07859.13 CBK19873.2 - 4.3e-05 23.5 0.0 0.00011 22.1 0.0 1.7 2 0 0 2 2 2 1 alpha/beta hydrolase fold FSH1 PF03959.13 CBK19873.2 - 0.00048 19.9 0.0 0.0011 18.7 0.0 1.7 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.7 CBK19873.2 - 0.00052 20.7 0.0 0.00066 20.3 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 CBK19873.2 - 0.0027 17.4 0.0 0.0063 16.2 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 CBK19873.2 - 0.029 13.6 0.0 0.14 11.4 0.0 1.9 2 0 0 2 2 2 0 Serine aminopeptidase, S33 DUF2974 PF11187.8 CBK19873.2 - 0.044 13.3 0.0 0.058 12.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Ureide_permease PF07168.11 CBK19873.2 - 0.079 11.7 0.0 0.11 11.2 0.0 1.1 1 0 0 1 1 1 0 Ureide permease AXE1 PF05448.12 CBK19873.2 - 0.087 11.5 0.0 0.12 11.0 0.0 1.2 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) Esterase_phd PF10503.9 CBK19873.2 - 0.098 12.1 0.1 0.61 9.5 0.1 2.0 1 1 0 1 1 1 0 Esterase PHB depolymerase DLH PF01738.18 CBK19873.2 - 0.12 11.9 0.1 0.16 11.5 0.1 1.2 1 0 0 1 1 1 0 Dienelactone hydrolase family DUF3530 PF12048.8 CBK19873.2 - 0.23 10.8 0.0 0.36 10.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3530) CDC50 PF03381.15 CBK19874.2 - 1.7e-68 231.2 0.0 2.5e-68 230.6 0.0 1.2 1 1 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family DUF241 PF03087.14 CBK19875.2 - 0.022 14.6 1.4 0.024 14.5 1.4 1.0 1 0 0 1 1 1 0 Arabidopsis protein of unknown function BAH PF01426.18 CBK19876.2 - 0.00031 20.6 0.0 0.00053 19.8 0.0 1.4 1 1 0 1 1 1 1 BAH domain Ribosomal_L22 PF00237.19 CBK19876.2 - 0.03 14.5 0.0 0.076 13.3 0.0 1.6 1 0 0 1 1 1 0 Ribosomal protein L22p/L17e tRNA-synt_1c PF00749.21 CBK19877.2 - 2e-99 332.4 1.8 2.8e-99 332.0 1.8 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.18 CBK19877.2 - 1.8e-36 125.6 0.2 3.6e-36 124.6 0.2 1.5 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain GST_C_3 PF14497.6 CBK19877.2 - 2.4e-06 27.7 0.1 2.8e-05 24.2 0.0 2.4 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain tRNA-synt_1e PF01406.19 CBK19877.2 - 0.01 15.2 0.1 0.022 14.1 0.1 1.5 1 0 0 1 1 1 0 tRNA synthetases class I (C) catalytic domain GST_C_2 PF13410.6 CBK19877.2 - 0.011 15.7 0.0 0.029 14.4 0.0 1.7 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 CBK19877.2 - 0.013 15.7 0.0 0.039 14.2 0.0 1.8 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain hSac2 PF12456.8 CBK19878.2 - 0.021 14.5 0.3 0.57 9.9 0.0 2.8 1 1 2 3 3 3 0 Inositol phosphatase LRR_4 PF12799.7 CBK19878.2 - 0.13 12.7 2.6 4.5 7.8 0.1 3.8 3 2 1 4 4 4 0 Leucine Rich repeats (2 copies) Sec63 PF02889.16 CBK19879.2 - 1.1e-110 368.9 8.5 2.1e-67 227.0 1.1 2.3 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.29 CBK19879.2 - 1.2e-49 168.4 2.2 2.4e-24 86.0 0.0 2.9 3 0 0 3 3 3 2 DEAD/DEAH box helicase ResIII PF04851.15 CBK19879.2 - 7e-28 97.8 0.0 1e-13 51.6 0.0 2.6 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Helicase_C PF00271.31 CBK19879.2 - 9.2e-14 51.7 0.0 6.5e-05 23.3 0.0 4.0 2 2 0 2 2 2 2 Helicase conserved C-terminal domain AAA_22 PF13401.6 CBK19879.2 - 1e-09 38.8 2.8 6.6e-05 23.2 0.0 3.3 3 0 0 3 3 3 2 AAA domain AAA PF00004.29 CBK19879.2 - 0.00011 22.7 1.5 0.082 13.3 0.0 3.5 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.6 CBK19879.2 - 0.0015 18.9 1.6 2.2 8.6 0.0 2.7 2 0 0 2 2 2 2 AAA domain UvrD-helicase PF00580.21 CBK19879.2 - 0.0027 17.3 3.0 0.84 9.1 0.0 3.3 3 0 0 3 3 3 1 UvrD/REP helicase N-terminal domain T2SSE PF00437.20 CBK19879.2 - 0.0076 15.3 0.0 0.69 8.9 0.0 2.4 2 0 0 2 2 2 1 Type II/IV secretion system protein PhoH PF02562.16 CBK19879.2 - 0.032 13.7 0.1 0.87 9.0 0.0 2.6 2 0 0 2 2 2 0 PhoH-like protein DUF2075 PF09848.9 CBK19879.2 - 0.054 12.7 0.0 5.7 6.1 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) HhH-GPD PF00730.25 CBK19880.2 - 1.3e-20 73.8 0.0 2.1e-20 73.2 0.0 1.3 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 CBK19880.2 - 4.6e-09 35.7 0.1 1.4e-08 34.1 0.1 1.8 2 0 0 2 2 2 1 Helix-hairpin-helix motif zf-4CXXC_R1 PF10497.9 CBK19881.2 - 0.0034 17.6 15.5 0.0057 16.9 15.5 1.4 1 0 0 1 1 1 1 Zinc-finger domain of monoamine-oxidase A repressor R1 DUF4790 PF16037.5 CBK19881.2 - 0.048 14.1 0.0 0.15 12.5 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4790) zf-RING_2 PF13639.6 CBK19882.2 - 3.5e-06 27.2 14.9 7.9e-06 26.1 14.9 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 CBK19882.2 - 6.9e-05 22.6 13.9 0.00013 21.8 13.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CBK19882.2 - 0.00016 21.6 17.0 0.00031 20.6 17.0 1.5 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 CBK19882.2 - 0.074 12.9 15.1 3.1 7.7 15.7 2.4 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 CBK19882.2 - 0.25 11.4 15.2 0.54 10.3 15.2 1.6 1 0 0 1 1 1 0 RING-type zinc-finger zf-C3HC4 PF00097.25 CBK19882.2 - 0.35 10.8 15.5 0.87 9.5 15.5 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 CBK19882.2 - 0.53 10.2 19.5 0.13 12.2 16.2 1.8 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) GAS PF13851.6 CBK19883.2 - 0.002 17.5 13.7 0.002 17.5 13.7 6.2 1 1 5 6 6 6 4 Growth-arrest specific micro-tubule binding CENP-F_leu_zip PF10473.9 CBK19883.2 - 0.0039 17.2 131.0 0.5 10.4 20.7 6.8 1 1 6 7 7 7 4 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF4201 PF13870.6 CBK19883.2 - 0.17 11.6 93.8 0.029 14.1 24.0 6.1 1 1 3 5 5 5 0 Domain of unknown function (DUF4201) ATG16 PF08614.11 CBK19883.2 - 0.26 11.5 137.3 0.37 11.0 24.3 6.2 1 1 3 5 5 5 0 Autophagy protein 16 (ATG16) Spc7 PF08317.11 CBK19883.2 - 0.35 9.7 120.0 0.34 9.7 22.0 5.4 1 1 2 4 4 4 0 Spc7 kinetochore protein Fez1 PF06818.15 CBK19883.2 - 4.3 7.7 113.3 1.7 9.1 18.6 5.5 1 1 4 5 5 5 0 Fez1 DUF3338 PF11819.8 CBK19884.2 - 0.055 13.5 0.0 0.065 13.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3338) FAM76 PF16046.5 CBK19884.2 - 0.22 10.8 0.4 0.24 10.7 0.4 1.1 1 0 0 1 1 1 0 FAM76 protein Glyco_hydro_20 PF00728.22 CBK19885.2 - 1.6e-76 258.0 10.2 5.6e-76 256.2 10.2 1.8 1 1 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.6 CBK19885.2 - 1.1e-21 78.0 0.3 1.6e-19 70.9 0.3 2.6 1 1 0 1 1 1 1 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.15 CBK19885.2 - 6.9e-07 30.1 0.0 1.4e-06 29.1 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 dUTPase PF00692.19 CBK19886.2 - 8.9e-38 128.9 0.0 8.8e-37 125.7 0.0 2.0 1 1 0 1 1 1 1 dUTPase ANP PF00212.18 CBK19886.2 - 0.3 11.3 0.2 0.3 11.3 0.2 2.5 2 1 1 3 3 3 0 Atrial natriuretic peptide tRNA-synt_1 PF00133.22 CBK19887.2 - 7.7e-219 727.9 0.0 1e-218 727.5 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 CBK19887.2 - 2.5e-23 82.7 0.0 5.3e-23 81.7 0.0 1.5 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 CBK19887.2 - 5.7e-15 55.0 0.9 2.5e-05 23.2 0.0 3.2 3 0 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1e PF01406.19 CBK19887.2 - 0.00014 21.3 0.0 0.00083 18.8 0.0 2.2 2 0 0 2 2 2 1 tRNA synthetases class I (C) catalytic domain MutS_V PF00488.21 CBK19888.2 - 2.1e-71 239.9 0.4 4.6e-71 238.8 0.4 1.6 1 0 0 1 1 1 1 MutS domain V S1-P1_nuclease PF02265.16 CBK19888.2 - 5.6e-37 127.9 0.0 8.7e-37 127.3 0.0 1.3 1 0 0 1 1 1 1 S1/P1 Nuclease MutS_I PF01624.20 CBK19888.2 - 3e-29 101.5 0.0 2.6e-28 98.5 0.0 2.5 1 1 0 1 1 1 1 MutS domain I MutS_III PF05192.18 CBK19888.2 - 4.9e-23 82.4 4.6 1.2e-22 81.1 1.1 2.6 2 0 0 2 2 2 1 MutS domain III MutS_II PF05188.17 CBK19888.2 - 3.2e-14 53.4 0.0 7.6e-14 52.2 0.0 1.7 1 0 0 1 1 1 1 MutS domain II MutS_IV PF05190.18 CBK19888.2 - 4.5e-09 36.5 0.0 1.2e-08 35.2 0.0 1.8 1 0 0 1 1 1 1 MutS family domain IV AAA_23 PF13476.6 CBK19888.2 - 0.28 11.7 2.8 0.56 10.7 1.2 2.4 2 1 0 2 2 2 0 AAA domain DUF1296 PF06972.11 CBK19888.2 - 0.45 10.7 2.0 1.1 9.4 2.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1296) zf-LITAF-like PF10601.9 CBK19889.2 - 1.1e-10 41.6 9.5 4.8e-06 26.7 2.6 2.2 1 1 1 2 2 2 2 LITAF-like zinc ribbon domain Zn_Tnp_IS1595 PF12760.7 CBK19889.2 - 0.024 14.6 1.6 1.6 8.7 0.1 2.3 2 0 0 2 2 2 0 Transposase zinc-ribbon domain Ribosomal_L32p PF01783.23 CBK19889.2 - 0.29 11.4 1.1 0.76 10.1 0.1 2.0 2 0 0 2 2 2 0 Ribosomal L32p protein family HRM PF02793.22 CBK19890.2 - 1.2e-08 35.1 5.6 5.1e-07 29.9 2.2 2.6 2 1 0 2 2 2 2 Hormone receptor domain RINGv PF12906.7 CBK19890.2 - 0.075 13.2 1.9 0.1 12.8 0.4 2.0 2 0 0 2 2 2 0 RING-variant domain UDPG_MGDP_dh_N PF03721.14 CBK19891.2 - 6.3e-39 133.5 0.1 1.6e-38 132.2 0.0 1.7 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh PF00984.19 CBK19891.2 - 1.1e-23 83.2 0.0 2.5e-23 82.1 0.0 1.6 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain UDPG_MGDP_dh_C PF03720.15 CBK19891.2 - 2.5e-22 79.3 0.5 9e-22 77.5 0.5 1.9 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain NAD_binding_2 PF03446.15 CBK19891.2 - 8.4e-06 26.0 0.3 6.7e-05 23.1 0.0 2.6 3 1 0 3 3 3 1 NAD binding domain of 6-phosphogluconate dehydrogenase 2-Hacid_dh_C PF02826.19 CBK19891.2 - 0.00057 19.3 0.3 0.27 10.6 0.0 2.4 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.18 CBK19891.2 - 0.0013 18.7 0.9 0.0062 16.4 0.0 2.5 3 1 0 3 3 3 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Runt PF00853.19 CBK19891.2 - 0.046 13.3 0.6 0.55 9.8 0.1 2.2 1 1 0 2 2 2 0 Runt domain Pyr_redox PF00070.27 CBK19891.2 - 0.18 12.4 1.2 1.2 9.8 0.4 2.7 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase UQ_con PF00179.26 CBK19892.2 - 7.6e-48 161.7 0.0 1e-47 161.3 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme DNAJ_related PF12339.8 CBK19892.2 - 0.077 13.2 0.1 0.11 12.7 0.1 1.2 1 0 0 1 1 1 0 DNA-J related protein ArfGap PF01412.18 CBK19893.2 - 2.6e-35 121.0 0.0 2.6e-35 121.0 0.0 2.1 3 0 0 3 3 3 1 Putative GTPase activating protein for Arf FoP_duplication PF13865.6 CBK19893.2 - 0.067 13.8 0.2 0.067 13.8 0.2 3.6 3 1 0 3 3 3 0 C-terminal duplication domain of Friend of PRMT1 Ribosomal_L44 PF00935.19 CBK19894.2 - 3e-32 110.9 13.1 3e-32 110.9 13.1 1.5 2 0 0 2 2 2 1 Ribosomal protein L44 NOB1_Zn_bind PF08772.11 CBK19894.2 - 0.017 15.2 1.9 0.017 15.2 1.9 1.9 1 1 0 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like Ribosomal_L33 PF00471.20 CBK19894.2 - 0.033 14.6 3.0 0.033 14.6 3.0 3.1 2 1 1 3 3 3 0 Ribosomal protein L33 HNH_5 PF14279.6 CBK19894.2 - 0.1 12.5 0.4 0.1 12.5 0.4 2.3 2 0 0 2 2 2 0 HNH endonuclease Melibiase_2 PF16499.5 CBK19895.2 - 1.2e-120 402.0 10.0 1.4e-120 401.8 10.0 1.0 1 0 0 1 1 1 1 Alpha galactosidase A Melibiase_C PF17801.1 CBK19895.2 - 8.9e-17 60.9 0.0 2.3e-16 59.6 0.0 1.7 1 0 0 1 1 1 1 Alpha galactosidase C-terminal beta sandwich domain Melibiase PF02065.18 CBK19895.2 - 3.9e-05 22.8 0.3 8.4e-05 21.7 0.1 1.6 2 0 0 2 2 2 1 Melibiase Melibiase_2_C PF17450.2 CBK19895.2 - 0.00011 22.3 0.0 0.00023 21.3 0.0 1.5 1 0 0 1 1 1 1 Alpha galactosidase A C-terminal beta sandwich domain Glyco_hydro_97 PF10566.9 CBK19895.2 - 0.065 12.5 0.1 0.099 11.9 0.1 1.2 1 0 0 1 1 1 0 Glycoside hydrolase 97 LRR_8 PF13855.6 CBK19897.2 - 0.0011 18.7 7.6 0.4 10.5 0.1 4.3 3 1 2 5 5 5 3 Leucine rich repeat hSac2 PF12456.8 CBK19897.2 - 0.034 13.8 0.3 4 7.2 0.0 3.4 1 1 3 4 4 4 0 Inositol phosphatase DNA_pol_B_2 PF03175.13 CBK19898.2 - 1.9e-15 56.7 10.4 1.8e-13 50.2 6.3 2.5 2 1 0 2 2 2 2 DNA polymerase type B, organellar and viral TPT PF03151.16 CBK19899.2 - 1.1e-32 113.6 27.0 1.3e-32 113.4 27.0 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 CBK19899.2 - 1e-10 41.9 38.2 7.9e-06 26.1 15.1 2.1 2 0 0 2 2 2 2 EamA-like transporter family DUF2633 PF11119.8 CBK19899.2 - 0.12 12.3 0.4 0.46 10.4 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2633) Sas10_Utp3 PF04000.15 CBK19900.2 - 7.6e-08 32.9 0.4 9.4e-08 32.6 0.4 1.2 1 0 0 1 1 1 1 Sas10/Utp3/C1D family EF-hand_14 PF17959.1 CBK19900.2 - 0.034 14.5 0.1 0.053 13.9 0.0 1.3 1 1 0 1 1 1 0 EF-hand domain Methyltransf_1N PF02870.15 CBK19900.2 - 0.1 13.4 0.0 0.15 12.9 0.0 1.3 1 0 0 1 1 1 0 6-O-methylguanine DNA methyltransferase, ribonuclease-like domain WES_acyltransf PF03007.16 CBK19901.2 - 4.9e-06 26.5 0.0 1.4e-05 25.0 0.0 1.6 2 0 0 2 2 2 1 Wax ester synthase-like Acyl-CoA acyltransferase domain AATase PF07247.12 CBK19901.2 - 0.043 12.4 0.0 0.14 10.7 0.0 1.7 1 1 0 2 2 2 0 Alcohol acetyltransferase Exo70 PF03081.15 CBK19902.2 - 3.1e-06 26.5 1.2 3.4e-06 26.3 1.2 1.0 1 0 0 1 1 1 1 Exo70 exocyst complex subunit DUF5407 PF17401.2 CBK19902.2 - 0.3 11.4 2.2 0.19 12.0 0.4 1.6 2 0 0 2 2 2 0 Family of unknown function (DUF5407) Beach PF02138.18 CBK19903.2 - 6e-91 304.6 0.1 8.5e-91 304.1 0.1 1.2 1 0 0 1 1 1 1 Beige/BEACH domain PH_BEACH PF14844.6 CBK19903.2 - 9.4e-08 32.1 0.0 2.2e-07 30.9 0.0 1.6 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH dUTPase PF00692.19 CBK19905.2 - 1.8e-38 131.1 0.0 1.8e-37 127.9 0.0 2.0 1 1 0 1 1 1 1 dUTPase Ribosomal_S25 PF03297.15 CBK19906.2 - 5.2e-28 97.2 1.2 5.2e-28 97.2 1.2 2.0 2 0 0 2 2 2 1 S25 ribosomal protein AbiEi_4 PF13338.6 CBK19906.2 - 0.09 13.0 0.1 0.19 11.9 0.1 1.5 1 0 0 1 1 1 0 Transcriptional regulator, AbiEi antitoxin YjbH PF06082.11 CBK19906.2 - 0.16 10.7 0.6 0.24 10.2 0.6 1.2 1 0 0 1 1 1 0 Exopolysaccharide biosynthesis protein YbjH Adaptin_N PF01602.20 CBK19907.2 - 9.3e-89 298.3 11.7 1.1e-88 298.1 11.7 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptin_C PF02296.16 CBK19907.2 - 1.9e-14 53.8 0.0 6e-14 52.2 0.0 1.9 1 0 0 1 1 1 1 Alpha adaptin AP2, C-terminal domain Alpha_adaptinC2 PF02883.20 CBK19907.2 - 1.8e-09 37.9 0.0 4e-09 36.8 0.0 1.6 1 0 0 1 1 1 1 Adaptin C-terminal domain Nop14 PF04147.12 CBK19907.2 - 3.4e-05 22.3 28.4 5.7e-05 21.6 28.4 1.4 1 0 0 1 1 1 1 Nop14-like family BUD22 PF09073.10 CBK19907.2 - 0.00039 19.9 19.3 0.00062 19.2 19.3 1.3 1 0 0 1 1 1 1 BUD22 SDA1 PF05285.12 CBK19907.2 - 0.00086 18.8 29.2 0.0015 18.0 29.2 1.4 1 0 0 1 1 1 1 SDA1 HEAT_2 PF13646.6 CBK19907.2 - 0.0011 19.3 0.4 0.26 11.7 0.0 3.7 3 1 1 4 4 3 1 HEAT repeats B2-adapt-app_C PF09066.10 CBK19907.2 - 0.096 12.8 0.0 0.33 11.0 0.0 1.9 1 0 0 1 1 1 0 Beta2-adaptin appendage, C-terminal sub-domain RTP1_C1 PF10363.9 CBK19907.2 - 0.11 12.7 1.4 0.32 11.2 0.2 2.5 2 0 0 2 2 1 0 Required for nuclear transport of RNA pol II C-terminus 1 CobT PF06213.12 CBK19907.2 - 0.28 10.5 34.9 0.62 9.4 34.9 1.5 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Cnd1 PF12717.7 CBK19907.2 - 0.29 11.2 11.5 2.9 7.9 0.4 4.0 4 1 0 4 4 3 0 non-SMC mitotic condensation complex subunit 1 Nop25 PF09805.9 CBK19907.2 - 0.32 11.5 18.7 0.93 10.0 18.7 1.9 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) Utp14 PF04615.13 CBK19907.2 - 0.4 9.2 20.4 0.79 8.2 20.4 1.4 1 0 0 1 1 1 0 Utp14 protein CDC45 PF02724.14 CBK19907.2 - 0.67 8.2 28.5 1.1 7.5 28.5 1.2 1 0 0 1 1 1 0 CDC45-like protein DUF913 PF06025.12 CBK19907.2 - 0.73 8.8 7.9 0.45 9.4 5.0 2.0 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) CNDH2_C PF16858.5 CBK19907.2 - 0.79 9.5 16.4 0.58 10.0 14.1 1.9 2 0 0 2 2 2 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term DUF2151 PF10221.9 CBK19907.2 - 0.9 8.1 8.4 1.5 7.4 8.4 1.3 1 0 0 1 1 1 0 Cell cycle and development regulator Zip PF02535.22 CBK19907.2 - 1.6 7.9 3.7 3.1 6.9 3.7 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter DUF2722 PF10846.8 CBK19907.2 - 2.9 6.7 14.6 4.6 6.1 14.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Presenilin PF01080.17 CBK19907.2 - 3.2 6.4 5.7 6.5 5.4 5.7 1.5 1 0 0 1 1 1 0 Presenilin DUF4746 PF15928.5 CBK19907.2 - 5 6.5 19.5 9.4 5.6 19.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) NPR3 PF03666.13 CBK19907.2 - 5.5 5.7 9.9 10 4.8 9.9 1.4 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Vfa1 PF08432.10 CBK19907.2 - 6.3 7.1 16.8 2.1 8.7 13.4 1.9 2 0 0 2 2 1 0 AAA-ATPase Vps4-associated protein 1 CCDC53 PF10152.9 CBK19907.2 - 7.3 7.0 10.5 15 6.0 8.6 2.2 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex CDC27 PF09507.10 CBK19907.2 - 9.9 5.4 22.4 17 4.6 22.4 1.3 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 UCH PF00443.29 CBK19908.2 - 7e-15 55.2 0.0 9.5e-15 54.8 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 CBK19908.2 - 0.051 13.2 0.1 0.084 12.5 0.1 1.3 1 0 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase TRAPPC-Trs85 PF12739.7 CBK19909.2 - 2e-27 96.2 8.3 1.5e-23 83.5 6.9 2.4 1 1 1 2 2 2 2 ER-Golgi trafficking TRAPP I complex 85 kDa subunit Gryzun PF07919.12 CBK19909.2 - 1.4e-05 24.1 0.0 2.1e-05 23.5 0.0 1.1 1 0 0 1 1 1 1 Gryzun, putative trafficking through Golgi TRAPPC9-Trs120 PF08626.11 CBK19909.2 - 0.00015 19.3 0.7 0.002 15.6 0.1 2.1 2 0 0 2 2 2 2 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit BatD PF13584.6 CBK19909.2 - 0.04 12.7 0.0 0.062 12.1 0.0 1.1 1 0 0 1 1 1 0 Oxygen tolerance MORN PF02493.20 CBK19910.2 - 1.6e-10 40.3 6.1 0.01 15.7 1.3 5.5 5 0 0 5 5 5 4 MORN repeat DUF4954 PF16314.5 CBK19911.2 - 5.8e-10 38.0 0.1 7.4e-10 37.6 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4954) APG6_N PF17675.1 CBK19912.2 - 0.003 18.1 35.1 0.0076 16.8 22.9 2.2 1 1 1 2 2 2 2 Apg6 coiled-coil region DUF4763 PF15960.5 CBK19912.2 - 0.019 14.2 35.1 0.12 11.7 17.0 2.6 1 1 1 3 3 3 0 Domain of unknown function (DUF4763) MAD PF05557.13 CBK19912.2 - 0.078 11.3 27.0 0.12 10.7 27.0 1.3 1 0 0 1 1 1 0 Mitotic checkpoint protein HAP1_N PF04849.13 CBK19912.2 - 0.28 10.4 29.4 0.37 9.9 29.4 1.1 1 0 0 1 1 1 0 HAP1 N-terminal conserved region Fib_alpha PF08702.10 CBK19912.2 - 0.42 10.8 21.8 0.44 10.7 15.3 3.1 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family GCSF PF16647.5 CBK19912.2 - 0.87 9.4 7.6 0.58 10.0 5.4 1.8 1 1 1 2 2 2 0 Granulocyte colony-stimulating factor Laminin_II PF06009.12 CBK19912.2 - 1.5 8.8 22.7 8.5 6.4 13.1 2.3 1 1 1 2 2 2 0 Laminin Domain II Atg14 PF10186.9 CBK19912.2 - 2 7.4 30.0 0.69 8.9 6.7 2.2 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 ADIP PF11559.8 CBK19912.2 - 2.4 8.2 34.0 2.6 8.1 13.3 2.3 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding LMBR1 PF04791.16 CBK19912.2 - 3 6.6 11.9 3.7 6.3 11.9 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein BRE1 PF08647.11 CBK19912.2 - 3.1 7.9 27.9 0.13 12.4 15.9 2.8 1 1 2 3 3 3 0 BRE1 E3 ubiquitin ligase Seryl_tRNA_N PF02403.22 CBK19912.2 - 3.1 8.1 19.8 6.3 7.1 2.2 3.2 1 1 2 3 3 3 0 Seryl-tRNA synthetase N-terminal domain DUF4400 PF14348.6 CBK19912.2 - 3.5 7.1 11.5 0.46 9.9 1.2 2.7 1 1 2 3 3 3 0 Domain of unknown function (DUF4400) Filament PF00038.21 CBK19912.2 - 3.6 7.1 27.7 0.98 8.9 13.0 2.2 1 1 1 2 2 2 0 Intermediate filament protein Osmo_CC PF08946.10 CBK19912.2 - 4 7.8 9.5 4.8 7.5 1.8 3.3 3 0 0 3 3 3 0 Osmosensory transporter coiled coil HAUS-augmin3 PF14932.6 CBK19912.2 - 4.4 6.8 31.9 1.2 8.6 9.7 2.2 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 3 Spc7 PF08317.11 CBK19912.2 - 4.6 6.0 28.8 3.2 6.6 15.5 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein DUF724 PF05266.14 CBK19912.2 - 4.7 7.0 22.9 5.9 6.7 10.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF724) DUF16 PF01519.16 CBK19912.2 - 8.2 7.0 20.9 21 5.7 8.9 2.4 1 1 1 2 2 2 0 Protein of unknown function DUF16 DUF4600 PF15372.6 CBK19912.2 - 8.5 6.8 23.0 0.15 12.5 10.8 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4600) Ribosomal_S13 PF00416.22 CBK19913.2 - 3.2e-36 124.6 0.3 3.5e-36 124.4 0.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S13/S18 DUF2746 PF10874.8 CBK19913.2 - 0.0021 18.4 0.0 0.0027 18.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2746) Period_C PF12114.8 CBK19913.2 - 0.079 12.5 0.0 0.095 12.3 0.0 1.1 1 0 0 1 1 1 0 Period protein 2/3C-terminal region ATG16 PF08614.11 CBK19914.2 - 0.32 11.2 28.8 0.25 11.6 4.7 2.8 2 1 1 3 3 3 0 Autophagy protein 16 (ATG16) DivIC PF04977.15 CBK19914.2 - 0.37 10.6 16.3 1.3 8.9 0.4 3.9 3 1 1 4 4 4 0 Septum formation initiator PRKG1_interact PF15898.5 CBK19914.2 - 1.2 10.1 26.4 0.098 13.6 11.0 3.2 3 0 0 3 3 3 0 cGMP-dependent protein kinase interacting domain DUF724 PF05266.14 CBK19914.2 - 1.8 8.3 15.2 0.52 10.1 4.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF724) FAM76 PF16046.5 CBK19914.2 - 5.8 6.2 18.8 0.55 9.5 0.8 2.6 3 1 0 3 3 3 0 FAM76 protein KASH_CCD PF14662.6 CBK19914.2 - 6.9 6.4 26.1 0.13 12.1 6.5 3.1 2 1 0 2 2 2 0 Coiled-coil region of CCDC155 or KASH UPF0242 PF06785.11 CBK19914.2 - 8.3 6.5 20.3 3.8 7.6 5.0 2.4 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus PP2C PF00481.21 CBK19915.2 - 2.8e-30 105.8 0.1 4.7e-30 105.1 0.1 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C DUF4200 PF13863.6 CBK19915.2 - 1.7 9.0 4.2 30 5.0 1.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) MMR_HSR1 PF01926.23 CBK19917.2 - 3.1e-25 88.5 0.0 6.3e-25 87.5 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP1_OBG PF01018.22 CBK19917.2 - 3.5e-24 85.2 4.7 1.3e-18 67.1 1.3 2.5 1 1 1 2 2 2 2 GTP1/OBG FeoB_N PF02421.18 CBK19917.2 - 1.2e-14 54.1 0.0 2.3e-14 53.2 0.0 1.5 1 0 0 1 1 1 1 Ferrous iron transport protein B Arf PF00025.21 CBK19917.2 - 9.5e-08 31.7 0.0 2.4e-07 30.4 0.0 1.6 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 CBK19917.2 - 0.00056 19.5 0.0 0.44 10.0 0.0 2.8 2 1 0 2 2 2 2 Elongation factor Tu GTP binding domain MeaB PF03308.16 CBK19917.2 - 0.0014 17.7 0.1 0.022 13.8 0.0 2.2 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB Ras PF00071.22 CBK19917.2 - 0.0056 16.3 0.0 0.03 13.9 0.0 2.1 1 1 0 1 1 1 1 Ras family NOG1 PF06858.14 CBK19917.2 - 0.0081 15.9 0.1 0.018 14.8 0.1 1.6 1 0 0 1 1 1 1 Nucleolar GTP-binding protein 1 (NOG1) MMR_HSR1_Xtn PF16897.5 CBK19917.2 - 0.0096 15.9 0.0 0.028 14.4 0.0 1.7 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain Dynamin_N PF00350.23 CBK19917.2 - 0.011 15.8 0.7 1.6 8.8 0.0 2.6 2 1 1 3 3 3 0 Dynamin family PCRF PF03462.18 CBK19917.2 - 0.034 14.0 0.5 0.055 13.3 0.5 1.3 1 0 0 1 1 1 0 PCRF domain RsgA_GTPase PF03193.16 CBK19917.2 - 0.044 13.7 0.0 12 5.8 0.0 2.4 2 0 0 2 2 2 0 RsgA GTPase Roc PF08477.13 CBK19917.2 - 0.096 12.9 0.4 13 6.0 0.0 3.1 3 1 1 4 4 4 0 Ras of Complex, Roc, domain of DAPkinase Ploopntkinase3 PF18751.1 CBK19917.2 - 0.13 12.2 0.0 0.21 11.5 0.0 1.3 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 Topoisom_I_N PF02919.15 CBK19918.2 - 0.67 9.4 4.5 1 8.8 4.5 1.2 1 0 0 1 1 1 0 Eukaryotic DNA topoisomerase I, DNA binding fragment Ferlin_C PF16165.5 CBK19918.2 - 1.7 8.5 8.8 3.1 7.7 8.8 1.3 1 0 0 1 1 1 0 Ferlin C-terminus Macoilin PF09726.9 CBK19918.2 - 4.8 5.6 17.2 7.1 5.1 17.2 1.2 1 0 0 1 1 1 0 Macoilin family Adap_comp_sub PF00928.21 CBK19919.2 - 2.4e-81 273.0 0.0 3e-81 272.7 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 CBK19919.2 - 3.5e-09 36.7 0.2 6.3e-09 35.9 0.2 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain muHD PF10291.9 CBK19919.2 - 0.0028 17.2 0.0 0.0044 16.5 0.0 1.3 1 0 0 1 1 1 1 Muniscin C-terminal mu homology domain Longin PF13774.6 CBK19919.2 - 0.062 13.4 0.1 0.14 12.2 0.1 1.6 1 0 0 1 1 1 0 Regulated-SNARE-like domain TMEM208_SND2 PF05620.11 CBK19920.2 - 9.4e-10 38.5 0.5 1.1e-09 38.4 0.5 1.0 1 0 0 1 1 1 1 SRP-independent targeting protein 2/TMEM208 AgrB PF04647.15 CBK19920.2 - 0.0053 16.1 0.3 0.0068 15.7 0.3 1.1 1 0 0 1 1 1 1 Accessory gene regulator B DUF5531 PF17671.1 CBK19920.2 - 0.042 13.7 0.1 0.049 13.5 0.1 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5531) PAP2 PF01569.21 CBK19921.2 - 1.3e-21 76.8 4.0 8.3e-21 74.2 2.6 2.4 2 1 0 2 2 2 1 PAP2 superfamily CDC27 PF09507.10 CBK19922.2 - 1.1 8.6 49.3 0.019 14.4 23.6 2.1 2 0 0 2 2 2 0 DNA polymerase subunit Cdc27 IMS PF00817.20 CBK19923.2 - 1.5e-36 125.7 0.0 2.4e-36 125.0 0.0 1.4 1 0 0 1 1 1 1 impB/mucB/samB family HHH_5 PF14520.6 CBK19923.2 - 0.015 15.8 0.0 0.076 13.6 0.0 2.0 2 0 0 2 2 2 0 Helix-hairpin-helix domain IMS_C PF11799.8 CBK19923.2 - 0.019 15.6 0.1 0.04 14.6 0.1 1.4 1 0 0 1 1 1 0 impB/mucB/samB family C-terminal domain Cdd1 PF11731.8 CBK19923.2 - 0.071 13.4 0.0 0.16 12.2 0.0 1.6 1 0 0 1 1 1 0 Pathogenicity locus mCpol PF18182.1 CBK19923.2 - 0.074 13.4 0.0 0.21 12.0 0.0 1.7 1 0 0 1 1 1 0 minimal CRISPR polymerase domain BRCT PF00533.26 CBK19924.2 - 0.0021 18.4 0.0 0.0027 18.0 0.0 1.3 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain LIG3_BRCT PF16759.5 CBK19924.2 - 0.0063 16.8 0.0 0.009 16.3 0.0 1.2 1 0 0 1 1 1 1 DNA ligase 3 BRCT domain BRCT_2 PF16589.5 CBK19924.2 - 0.0064 16.9 0.0 0.0083 16.5 0.0 1.2 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain PTCB-BRCT PF12738.7 CBK19924.2 - 0.014 15.3 0.0 0.022 14.7 0.0 1.4 1 0 0 1 1 1 0 twin BRCT domain CVNH PF08881.10 CBK19924.2 - 0.073 13.8 0.0 0.082 13.6 0.0 1.1 1 0 0 1 1 1 0 CVNH domain SF1-HH PF16275.5 CBK19926.2 - 1.2e-22 80.3 1.5 2e-22 79.6 0.1 2.1 2 0 0 2 2 2 1 Splicing factor 1 helix-hairpin domain KH_1 PF00013.29 CBK19926.2 - 1.4e-09 37.6 1.0 3e-09 36.6 1.0 1.6 1 0 0 1 1 1 1 KH domain zf-CCHC PF00098.23 CBK19926.2 - 0.0055 16.7 3.1 0.0088 16.1 3.1 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-C2H2_10 PF16588.5 CBK19926.2 - 0.028 14.2 1.5 0.052 13.3 1.5 1.4 1 0 0 1 1 1 0 C2H2 zinc-finger zinc_ribbon_2 PF13240.6 CBK19926.2 - 0.047 13.4 0.2 0.096 12.4 0.2 1.5 1 0 0 1 1 1 0 zinc-ribbon domain zf-CCHC_3 PF13917.6 CBK19926.2 - 0.061 13.3 1.4 0.16 11.9 1.4 1.7 1 0 0 1 1 1 0 Zinc knuckle RNase_H2_suC PF08615.11 CBK19927.2 - 5.2e-10 39.6 0.1 3.5e-08 33.7 0.0 2.1 1 1 1 2 2 2 2 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) Cpn60_TCP1 PF00118.24 CBK19928.2 - 3e-149 497.8 10.4 3.4e-149 497.6 10.4 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family MORN PF02493.20 CBK19929.2 - 4.8e-05 23.0 16.6 0.043 13.7 0.4 5.3 4 1 0 4 4 4 3 MORN repeat LRR_8 PF13855.6 CBK19929.2 - 0.029 14.1 5.7 0.75 9.6 0.1 3.8 4 0 0 4 4 4 0 Leucine rich repeat Thr_synth_N PF14821.6 CBK19930.2 - 6.3e-23 80.8 0.1 1.6e-22 79.5 0.0 1.7 2 0 0 2 2 2 1 Threonine synthase N terminus Carboxyl_trans PF01039.22 CBK19931.2 - 5e-190 632.4 0.1 5.8e-190 632.1 0.1 1.0 1 0 0 1 1 1 1 Carboxyl transferase domain MdcE PF06833.11 CBK19931.2 - 0.0094 15.5 0.0 0.03 13.8 0.0 1.8 3 0 0 3 3 3 1 Malonate decarboxylase gamma subunit (MdcE) DUF3718 PF12514.8 CBK19932.2 - 2.1 8.5 4.9 32 4.8 0.2 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3718) Ribosomal_L13e PF01294.18 CBK19933.2 - 2.8e-41 141.4 0.0 4e-41 140.8 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L13e SIR2 PF02146.17 CBK19934.2 - 1.2e-54 185.0 0.0 2.4e-54 183.9 0.0 1.5 2 0 0 2 2 2 1 Sir2 family IF-2B PF01008.17 CBK19935.2 - 0.018 14.3 0.1 0.033 13.4 0.1 1.4 1 0 0 1 1 1 0 Initiation factor 2 subunit family FdsD PF11390.8 CBK19935.2 - 0.065 13.6 0.3 4.8 7.6 0.2 3.0 3 0 0 3 3 3 0 NADH-dependant formate dehydrogenase delta subunit FdsD DUF4704 PF15787.5 CBK19935.2 - 2.4 7.3 20.1 0.0086 15.3 2.2 3.8 4 0 0 4 4 4 0 Domain of unknown function (DUF4704) Flt3_lig PF02947.14 CBK19936.2 - 0.036 14.2 0.0 0.06 13.5 0.0 1.3 1 0 0 1 1 1 0 flt3 ligand LETM1 PF07766.13 CBK19937.2 - 1.3e-56 191.9 0.0 2.2e-56 191.2 0.0 1.4 1 0 0 1 1 1 1 LETM1-like protein YL1 PF05764.13 CBK19938.2 - 3.6e-07 30.6 14.0 8.1e-07 29.4 14.0 1.5 1 0 0 1 1 1 1 YL1 nuclear protein zf-HIT PF04438.16 CBK19938.2 - 0.00011 21.9 3.1 0.00027 20.7 0.3 2.3 2 0 0 2 2 2 1 HIT zinc finger YL1_C PF08265.11 CBK19938.2 - 0.19 11.5 1.7 0.28 11.0 0.1 2.1 3 0 0 3 3 3 0 YL1 nuclear protein C-terminal domain Vps39_2 PF10367.9 CBK19939.2 - 3.3e-18 66.1 1.2 1.1e-17 64.5 1.2 1.9 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 Vps39_1 PF10366.9 CBK19939.2 - 6.6e-10 39.2 0.0 3.2e-09 37.0 0.0 2.3 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 1 PPR PF01535.20 CBK19939.2 - 0.00079 19.5 0.0 0.26 11.6 0.0 3.8 4 0 0 4 4 4 1 PPR repeat Clathrin PF00637.20 CBK19939.2 - 0.0029 17.5 0.0 0.21 11.5 0.0 3.0 3 0 0 3 3 3 1 Region in Clathrin and VPS WASH_WAHD PF11945.8 CBK19939.2 - 0.13 11.7 0.0 0.21 11.1 0.0 1.2 1 0 0 1 1 1 0 WAHD domain of WASH complex PPR_2 PF13041.6 CBK19939.2 - 0.17 12.1 0.0 5.5 7.3 0.0 2.6 2 0 0 2 2 2 0 PPR repeat family Ribosomal_L23 PF00276.20 CBK19940.2 - 1.1e-15 57.8 2.6 3.9e-15 56.0 2.6 1.7 1 1 0 1 1 1 1 Ribosomal protein L23 IL31 PF15209.6 CBK19940.2 - 0.049 13.4 0.2 0.059 13.2 0.2 1.1 1 0 0 1 1 1 0 Interleukin 31 MFS_1 PF07690.16 CBK19941.2 - 1.5e-09 37.3 32.5 3.5e-08 32.8 13.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DmpG_comm PF07836.11 CBK19941.2 - 0.058 12.9 0.2 0.14 11.7 0.0 1.7 2 0 0 2 2 2 0 DmpG-like communication domain TBP PF00352.21 CBK19942.2 - 8e-56 186.0 0.1 9e-28 96.1 0.0 2.1 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.8 CBK19942.2 - 7.3e-08 32.4 0.0 0.0084 16.2 0.0 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF3378) ADH_zinc_N PF00107.26 CBK19943.2 - 8.9e-15 54.8 0.6 5.7e-14 52.2 0.1 2.1 2 1 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 CBK19943.2 - 4e-09 36.3 0.0 7.4e-09 35.5 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 CBK19943.2 - 0.00083 20.4 0.0 0.0015 19.6 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_2 PF16884.5 CBK19943.2 - 0.0039 17.1 0.0 0.0086 16.0 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase Tubulin PF00091.25 CBK19943.2 - 0.026 14.7 0.1 0.043 14.0 0.1 1.3 1 0 0 1 1 1 0 Tubulin/FtsZ family, GTPase domain Glycos_transf_N PF04413.16 CBK19943.2 - 0.16 11.6 0.0 0.23 11.1 0.0 1.2 1 0 0 1 1 1 0 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) Synaptobrevin PF00957.21 CBK19944.2 - 1.3e-30 105.0 2.1 1.3e-30 105.0 2.1 1.5 2 0 0 2 2 2 1 Synaptobrevin Longin PF13774.6 CBK19944.2 - 1.1e-20 73.4 0.2 1.8e-20 72.7 0.2 1.3 1 0 0 1 1 1 1 Regulated-SNARE-like domain GP41 PF00517.17 CBK19944.2 - 0.0025 17.7 0.1 0.0035 17.3 0.1 1.2 1 0 0 1 1 1 1 Retroviral envelope protein Nyv1_N PF09426.10 CBK19944.2 - 0.053 13.5 0.1 0.098 12.7 0.1 1.4 1 0 0 1 1 1 0 Vacuolar R-SNARE Nyv1 N terminal MSC PF09402.10 CBK19944.2 - 0.071 12.6 0.4 0.095 12.1 0.4 1.1 1 0 0 1 1 1 0 Man1-Src1p-C-terminal domain Phage_GPO PF05929.11 CBK19944.2 - 0.1 12.2 0.2 0.14 11.8 0.2 1.2 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase DUF2433 PF10360.9 CBK19944.2 - 0.13 12.4 1.3 0.47 10.6 1.3 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2433) OppC_N PF12911.7 CBK19944.2 - 1.1 9.3 3.8 2.2 8.3 3.8 1.4 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C SieB PF14163.6 CBK19945.2 - 3.1 7.3 3.9 6.2 6.3 3.9 1.5 1 0 0 1 1 1 0 Super-infection exclusion protein B TPR_2 PF07719.17 CBK19946.2 - 1e-11 44.0 17.1 5.6e-05 22.9 0.3 5.3 5 1 1 6 6 5 3 Tetratricopeptide repeat TPR_16 PF13432.6 CBK19946.2 - 2.2e-09 37.8 10.3 2e-07 31.6 3.1 4.0 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.28 CBK19946.2 - 3.1e-09 36.3 14.5 2.3e-05 24.0 0.5 4.6 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_14 PF13428.6 CBK19946.2 - 3.2e-08 33.7 8.3 0.018 15.9 0.7 4.2 3 1 1 4 4 3 3 Tetratricopeptide repeat TPR_9 PF13371.6 CBK19946.2 - 5.9e-08 32.8 2.4 2.4e-07 30.8 1.5 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.6 CBK19946.2 - 1.4e-07 31.9 8.9 1.7e-05 25.3 4.3 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 CBK19946.2 - 2.3e-07 30.8 9.3 0.00039 20.4 1.1 4.1 4 0 0 4 4 4 2 Fis1 C-terminal tetratricopeptide repeat TPR_12 PF13424.6 CBK19946.2 - 3.5e-06 27.2 10.1 0.002 18.4 0.7 4.0 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.6 CBK19946.2 - 2.3e-05 23.9 15.3 0.0015 18.2 1.7 4.0 4 0 0 4 4 4 2 TPR repeat SRP_TPR_like PF17004.5 CBK19946.2 - 5.5e-05 23.2 7.6 0.047 13.7 0.8 3.0 3 1 0 3 3 3 2 Putative TPR-like repeat TPR_8 PF13181.6 CBK19946.2 - 0.00026 21.0 10.8 0.087 13.1 0.1 5.2 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_7 PF13176.6 CBK19946.2 - 0.00048 20.0 1.0 6.2 7.1 0.0 4.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.6 CBK19946.2 - 0.00055 20.4 5.1 0.84 10.4 0.1 4.4 3 0 0 3 3 3 2 Tetratricopeptide repeat ANAPC3 PF12895.7 CBK19946.2 - 0.02 15.1 4.4 0.02 15.1 4.4 3.9 2 1 2 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 DUF4843 PF16132.5 CBK19946.2 - 0.077 12.6 0.0 0.18 11.4 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4843) TPR_17 PF13431.6 CBK19946.2 - 0.079 13.4 8.8 32 5.2 0.1 5.1 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_18 PF13512.6 CBK19946.2 - 0.36 10.9 6.3 0.36 10.9 1.5 2.5 2 1 1 3 3 3 0 Tetratricopeptide repeat Diphthami_syn_2 PF01902.17 CBK19947.2 - 1.8e-40 138.8 0.0 3.7e-40 137.8 0.0 1.5 1 1 0 1 1 1 1 Diphthamide synthase tRNA_Me_trans PF03054.16 CBK19947.2 - 0.051 12.4 0.1 0.15 10.8 0.1 1.7 2 0 0 2 2 2 0 tRNA methyl transferase DUF601 PF04642.12 CBK19947.2 - 0.18 11.3 0.0 0.26 10.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF601 KH_1 PF00013.29 CBK19949.2 - 6.8e-43 144.3 16.9 3.5e-16 58.8 0.2 3.5 3 0 0 3 3 3 3 KH domain KH_4 PF13083.6 CBK19949.2 - 1.7e-08 34.2 2.3 0.038 13.9 0.0 3.4 3 0 0 3 3 3 3 KH domain KH_2 PF07650.17 CBK19949.2 - 2.5e-07 30.4 6.8 0.0066 16.3 0.0 3.9 2 1 0 3 3 3 3 KH domain KH_5 PF13184.6 CBK19949.2 - 0.00046 20.2 2.0 1.9 8.6 0.1 3.7 3 0 0 3 3 3 2 NusA-like KH domain MOEP19 PF16005.5 CBK19949.2 - 0.027 14.5 0.2 3.1 7.9 0.1 3.0 3 0 0 3 3 3 0 KH-like RNA-binding domain HemN_C PF06969.16 CBK19949.2 - 0.062 13.4 0.0 0.12 12.4 0.0 1.4 1 0 0 1 1 1 0 HemN C-terminal domain Band_7 PF01145.25 CBK19951.2 - 2.5e-16 60.2 0.2 4.5e-16 59.4 0.2 1.5 1 0 0 1 1 1 1 SPFH domain / Band 7 family Methyltransf_23 PF13489.6 CBK19951.2 - 0.076 12.8 0.0 0.14 11.9 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain Band_7_1 PF13421.6 CBK19951.2 - 0.093 12.4 0.1 0.15 11.8 0.1 1.3 1 0 0 1 1 1 0 SPFH domain-Band 7 family Imm68 PF15583.6 CBK19951.2 - 0.12 12.6 0.0 0.9 9.7 0.0 2.1 2 0 0 2 2 2 0 Immunity protein 68 NGP1NT PF08153.12 CBK19952.2 - 1e-45 155.0 0.4 3.5e-45 153.4 0.4 1.9 1 0 0 1 1 1 1 NGP1NT (NUC091) domain MMR_HSR1 PF01926.23 CBK19952.2 - 4.4e-19 68.7 0.4 3.2e-15 56.2 0.0 2.9 2 1 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.18 CBK19952.2 - 2.3e-06 27.3 0.2 1.8e-05 24.3 0.0 2.4 3 0 0 3 3 3 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 CBK19952.2 - 1.2e-05 25.2 0.0 4.6e-05 23.4 0.0 1.9 1 1 0 1 1 1 1 RsgA GTPase Arf PF00025.21 CBK19952.2 - 0.004 16.6 0.6 0.23 10.9 0.0 2.6 2 1 0 2 2 2 1 ADP-ribosylation factor family Roc PF08477.13 CBK19952.2 - 0.0096 16.1 0.1 5.5 7.2 0.0 2.6 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase cobW PF02492.19 CBK19952.2 - 0.052 13.1 0.0 0.38 10.3 0.0 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain MRPL52 PF18699.1 CBK19952.2 - 1.9 8.7 9.1 1.1 9.5 0.6 2.6 2 0 0 2 2 2 0 Mitoribosomal protein mL52 Dynamin_N PF00350.23 CBK19952.2 - 2.7 8.0 10.6 7.6 6.6 4.4 4.1 2 2 0 2 2 2 0 Dynamin family Ribosomal_L36e PF01158.18 CBK19953.2 - 1.7e-27 95.5 7.8 1.9e-27 95.3 7.8 1.0 1 0 0 1 1 1 1 Ribosomal protein L36e Dak2 PF02734.17 CBK19953.2 - 0.043 13.7 0.2 0.047 13.6 0.2 1.1 1 0 0 1 1 1 0 DAK2 domain D5_N PF08706.11 CBK19953.2 - 0.11 12.8 2.0 0.12 12.6 2.0 1.1 1 0 0 1 1 1 0 D5 N terminal like Ribosomal_L13e PF01294.18 CBK19954.2 - 7.8e-36 123.6 0.1 2.3e-35 122.1 0.1 1.7 1 1 0 1 1 1 1 Ribosomal protein L13e HSP70 PF00012.20 CBK19955.2 - 4.8e-74 249.6 0.0 6.9e-74 249.1 0.0 1.1 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 CBK19955.2 - 5.1e-13 48.5 0.0 1.5e-10 40.4 0.0 2.3 2 0 0 2 2 2 2 MreB/Mbl protein DDR PF08841.10 CBK19955.2 - 0.076 12.0 0.0 3.8 6.4 0.0 2.2 2 0 0 2 2 2 0 Diol dehydratase reactivase ATPase-like domain tRNA-synt_2b PF00587.25 CBK19956.2 - 6.7e-39 133.7 0.1 1.1e-38 133.0 0.1 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.22 CBK19956.2 - 9.7e-24 83.7 4.7 1.9e-23 82.8 4.7 1.4 1 0 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain L_lactis_ph-MCP PF06673.11 CBK19956.2 - 0.31 10.0 4.7 0.51 9.3 4.7 1.3 1 0 0 1 1 1 0 Lactococcus lactis bacteriophage major capsid protein RRM_1 PF00076.22 CBK19957.2 - 1.9e-10 40.4 0.8 3.3e-10 39.7 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Patatin PF01734.22 CBK19958.2 - 1.1e-14 55.2 3.8 8.3e-13 49.0 2.5 2.5 2 1 0 2 2 2 1 Patatin-like phospholipase DHHC PF01529.20 CBK19959.2 - 8e-23 81.0 13.7 8e-23 81.0 13.7 1.4 1 1 0 1 1 1 1 DHHC palmitoyltransferase zf-ribbon_3 PF13248.6 CBK19959.2 - 0.01 15.2 4.6 0.01 15.2 4.6 2.7 3 0 0 3 3 3 0 zinc-ribbon domain DUF35_N PF12172.8 CBK19959.2 - 0.031 14.2 3.9 0.1 12.5 3.9 1.9 1 0 0 1 1 1 0 Rubredoxin-like zinc ribbon domain (DUF35_N) CDC24_OB3 PF17244.2 CBK19959.2 - 0.29 10.8 2.2 0.34 10.6 2.2 1.1 1 0 0 1 1 1 0 Cell division control protein 24, OB domain 3 C1_1 PF00130.22 CBK19959.2 - 0.53 10.2 12.3 1.3 9.0 7.8 2.4 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-tcix PF14952.6 CBK19959.2 - 1.4 8.6 6.2 2.8 7.6 6.2 1.6 1 0 0 1 1 1 0 Putative treble-clef, zinc-finger, Zn-binding AAA PF00004.29 CBK19960.2 - 5.7e-38 130.3 0.4 1.4e-37 129.0 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CBK19960.2 - 1.5e-13 50.3 0.5 3.1e-13 49.3 0.5 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_2 PF07724.14 CBK19960.2 - 2.4e-07 31.0 0.0 4.6e-07 30.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) Prot_ATP_ID_OB PF16450.5 CBK19960.2 - 4e-07 29.9 0.0 8.8e-07 28.8 0.0 1.6 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_16 PF13191.6 CBK19960.2 - 2.3e-06 28.1 2.1 1.6e-05 25.3 0.1 2.5 2 1 0 2 2 2 1 AAA ATPase domain AAA_5 PF07728.14 CBK19960.2 - 2.6e-06 27.5 0.5 8.4e-05 22.6 0.0 3.2 2 2 1 3 3 2 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 CBK19960.2 - 6.1e-05 23.3 1.6 0.0045 17.3 0.0 2.6 2 1 1 3 3 2 1 AAA domain AAA_7 PF12775.7 CBK19960.2 - 0.00014 21.4 0.0 0.00028 20.5 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region RuvB_N PF05496.12 CBK19960.2 - 0.00027 20.7 0.1 0.0011 18.7 0.1 2.1 2 1 0 2 2 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_24 PF13479.6 CBK19960.2 - 0.00034 20.4 0.0 0.00058 19.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.13 CBK19960.2 - 0.0006 19.1 0.8 0.028 13.7 0.0 2.4 2 1 0 2 2 2 1 TIP49 P-loop domain ATPase_2 PF01637.18 CBK19960.2 - 0.0011 18.9 0.7 0.64 9.9 0.0 2.8 2 1 1 3 3 3 1 ATPase domain predominantly from Archaea Sigma54_activat PF00158.26 CBK19960.2 - 0.0019 17.9 0.1 0.011 15.5 0.1 2.2 1 1 0 1 1 1 1 Sigma-54 interaction domain IstB_IS21 PF01695.17 CBK19960.2 - 0.0026 17.5 0.0 0.0062 16.3 0.0 1.7 2 0 0 2 2 1 1 IstB-like ATP binding protein AAA_18 PF13238.6 CBK19960.2 - 0.004 17.7 0.1 0.014 16.0 0.0 2.0 2 0 0 2 2 1 1 AAA domain AAA_33 PF13671.6 CBK19960.2 - 0.0055 16.9 0.0 0.011 15.9 0.0 1.6 1 1 0 1 1 1 1 AAA domain ATPase PF06745.13 CBK19960.2 - 0.0067 15.8 0.2 0.026 13.9 0.0 1.9 2 1 0 2 2 2 1 KaiC Mg_chelatase PF01078.21 CBK19960.2 - 0.011 15.2 0.0 0.026 13.9 0.0 1.7 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.22 CBK19960.2 - 0.011 16.2 0.0 0.27 11.7 0.0 2.6 2 0 0 2 2 2 0 RNA helicase AAA_14 PF13173.6 CBK19960.2 - 0.014 15.4 0.0 0.044 13.8 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_3 PF07726.11 CBK19960.2 - 0.062 13.2 0.0 0.14 12.0 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF815 PF05673.13 CBK19960.2 - 0.072 12.2 0.1 0.36 10.0 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF815) PhoH PF02562.16 CBK19960.2 - 0.084 12.3 0.1 0.19 11.1 0.1 1.6 1 0 0 1 1 1 0 PhoH-like protein TsaE PF02367.17 CBK19960.2 - 0.087 12.8 0.0 0.17 11.9 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Zeta_toxin PF06414.12 CBK19960.2 - 0.1 11.9 0.0 0.23 10.7 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin Bac_DnaA PF00308.18 CBK19960.2 - 0.11 12.3 0.0 0.3 10.9 0.0 1.7 2 0 0 2 2 2 0 Bacterial dnaA protein AAA_11 PF13086.6 CBK19960.2 - 0.12 12.2 0.2 0.87 9.3 0.0 2.2 2 0 0 2 2 2 0 AAA domain Hydin_ADK PF17213.3 CBK19960.2 - 0.14 12.5 0.0 0.28 11.5 0.0 1.5 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain NPV_P10 PF05531.12 CBK19960.2 - 0.15 12.5 0.8 2.2 8.8 0.5 2.3 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein AAA_25 PF13481.6 CBK19960.2 - 0.2 11.2 0.3 0.57 9.7 0.0 1.9 3 0 0 3 3 1 0 AAA domain FlxA PF14282.6 CBK19960.2 - 0.47 10.5 2.8 3.7 7.6 1.2 2.4 2 0 0 2 2 2 0 FlxA-like protein HSP70 PF00012.20 CBK19961.2 - 5.6e-11 41.4 0.0 7.3e-11 41.0 0.0 1.2 1 0 0 1 1 1 1 Hsp70 protein tRNA-synt_2b PF00587.25 CBK19962.2 - 6.6e-39 133.7 0.1 1e-38 133.1 0.1 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.22 CBK19962.2 - 5.7e-18 65.1 1.8 1.1e-17 64.2 1.8 1.4 1 0 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain LRRFIP PF09738.9 CBK19962.2 - 0.11 12.0 2.0 0.18 11.3 2.0 1.2 1 0 0 1 1 1 0 LRRFIP family Gpr1_Fun34_YaaH PF01184.19 CBK19963.2 - 0.022 14.3 1.7 0.022 14.3 1.7 1.0 1 0 0 1 1 1 0 GPR1/FUN34/yaaH family MBOAT PF03062.19 CBK19963.2 - 0.034 13.5 1.9 0.036 13.4 1.9 1.1 1 0 0 1 1 1 0 MBOAT, membrane-bound O-acyltransferase family VHS PF00790.19 CBK19965.2 - 1.4e-06 28.2 0.0 2.4e-06 27.4 0.0 1.4 1 0 0 1 1 1 1 VHS domain Ago_hook PF10427.9 CBK19966.2 - 6.1 7.4 15.0 19 5.7 1.6 3.8 2 2 1 3 3 3 0 Argonaute hook Phage_stabilise PF11134.8 CBK19969.2 - 0.023 13.6 0.0 0.024 13.5 0.0 1.1 1 0 0 1 1 1 0 Phage stabilisation protein CSD PF00313.22 CBK19969.2 - 0.031 14.1 0.1 0.046 13.6 0.1 1.3 1 0 0 1 1 1 0 'Cold-shock' DNA-binding domain RRM_1 PF00076.22 CBK19970.2 - 5.1e-66 218.4 0.1 6.1e-19 67.6 0.0 4.6 5 0 0 5 5 5 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 CBK19970.2 - 3.9e-10 39.4 0.0 0.023 14.3 0.0 4.4 3 1 1 4 4 4 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 CBK19970.2 - 5.1e-07 29.5 0.0 0.13 12.1 0.0 4.1 5 0 0 5 5 5 2 Occluded RNA-recognition motif Limkain-b1 PF11608.8 CBK19970.2 - 5.4e-05 23.2 0.1 4.4 7.5 0.0 4.8 4 1 0 4 4 4 2 Limkain b1 Nup35_RRM_2 PF14605.6 CBK19970.2 - 0.00023 21.1 0.0 0.77 9.8 0.1 3.5 3 0 0 3 3 3 1 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.11 CBK19970.2 - 0.00096 19.2 0.1 1.4 9.0 0.0 4.1 3 1 1 4 4 4 1 RNA binding motif RL PF17797.1 CBK19970.2 - 0.017 15.1 0.1 13 5.9 0.0 3.3 4 0 0 4 4 4 0 RL domain RRM_8 PF11835.8 CBK19970.2 - 0.1 12.8 0.3 0.77 10.0 0.0 2.5 3 0 0 3 3 3 0 RRM-like domain Macoilin PF09726.9 CBK19970.2 - 1 7.8 12.8 1.4 7.4 4.5 2.1 2 0 0 2 2 2 0 Macoilin family Apt1 PF10351.9 CBK19970.2 - 7.5 5.3 16.9 0.59 8.9 3.2 2.2 2 0 0 2 2 2 0 Golgi-body localisation protein domain Zip PF02535.22 CBK19970.2 - 7.7 5.6 5.5 14 4.7 0.5 2.1 2 0 0 2 2 2 0 ZIP Zinc transporter RRM_1 PF00076.22 CBK19971.2 - 5.7e-05 22.8 0.0 0.00015 21.5 0.0 1.7 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-C2H2_10 PF16588.5 CBK19971.2 - 0.049 13.4 1.7 0.081 12.7 1.7 1.3 1 0 0 1 1 1 0 C2H2 zinc-finger Ribosomal_S9 PF00380.19 CBK19972.2 - 5.7e-31 107.5 0.3 6.6e-31 107.4 0.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S9/S16 Peptidase_M1_N PF17900.1 CBK19973.2 - 0.0002 21.6 0.1 0.00053 20.2 0.0 1.7 2 0 0 2 2 2 1 Peptidase M1 N-terminal domain DUF2271 PF10029.9 CBK19976.2 - 0.039 13.6 0.0 0.048 13.3 0.0 1.2 1 0 0 1 1 1 0 Predicted periplasmic protein (DUF2271) Osmo_CC PF08946.10 CBK19976.2 - 0.046 14.0 0.0 0.093 13.0 0.0 1.5 1 1 0 1 1 1 0 Osmosensory transporter coiled coil DJ-1_PfpI PF01965.24 CBK19977.2 - 1.2e-44 152.0 0.3 1.4e-44 151.8 0.3 1.0 1 0 0 1 1 1 1 DJ-1/PfpI family ThiJ_like PF17124.5 CBK19977.2 - 0.033 13.9 0.0 0.044 13.5 0.0 1.3 1 0 0 1 1 1 0 ThiJ/PfpI family-like GATase_3 PF07685.14 CBK19977.2 - 0.078 12.6 0.0 0.18 11.3 0.0 1.6 2 0 0 2 2 2 0 CobB/CobQ-like glutamine amidotransferase domain LRR_8 PF13855.6 CBK19978.2 - 1.1e-05 25.1 2.1 0.00024 20.8 0.2 3.0 2 1 1 3 3 3 1 Leucine rich repeat LRR_4 PF12799.7 CBK19978.2 - 0.0022 18.4 2.9 3 8.4 0.3 3.8 2 1 2 4 4 4 2 Leucine Rich repeats (2 copies) Pax7 PF12360.8 CBK19978.2 - 0.05 13.8 0.1 0.19 11.9 0.1 2.0 1 0 0 1 1 1 0 Paired box protein 7 LRR_1 PF00560.33 CBK19978.2 - 0.4 11.4 2.2 39 5.3 0.0 4.2 3 1 0 3 3 3 0 Leucine Rich Repeat DUF563 PF04577.14 CBK19979.2 - 5.2e-16 59.4 0.1 7e-16 59.0 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF563) Proteasome PF00227.26 CBK19980.2 - 7e-32 110.4 0.1 9.9e-32 110.0 0.1 1.2 1 0 0 1 1 1 1 Proteasome subunit Metallophos PF00149.28 CBK19981.2 - 5.2e-35 121.8 0.1 6.8e-35 121.4 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 CBK19981.2 - 0.0015 18.9 0.6 0.0037 17.7 0.6 1.6 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain NTPase_I-T PF01931.18 CBK19982.2 - 1.1e-56 191.1 0.0 1.3e-56 190.9 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF84 DnaJ PF00226.31 CBK19983.2 - 2.5e-17 62.8 0.2 5.1e-17 61.7 0.2 1.6 1 0 0 1 1 1 1 DnaJ domain Sec63 PF02889.16 CBK19983.2 - 2.1e-11 43.5 0.4 2.9e-11 43.0 0.4 1.2 1 0 0 1 1 1 1 Sec63 Brl domain EphA2_TM PF14575.6 CBK19983.2 - 0.035 15.0 0.4 4 8.4 0.0 3.3 3 0 0 3 3 3 0 Ephrin type-A receptor 2 transmembrane domain SLATT_5 PF18160.1 CBK19983.2 - 0.51 9.6 2.5 0.55 9.5 0.2 2.2 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain family 5 SIT PF15330.6 CBK19983.2 - 1.2 9.6 0.0 1.2 9.6 0.0 2.8 3 1 1 4 4 4 0 SHP2-interacting transmembrane adaptor protein, SIT ER_lumen_recept PF00810.18 CBK19984.2 - 5.3e-32 111.7 4.5 5.3e-32 111.7 4.5 2.6 3 0 0 3 3 3 1 ER lumen protein retaining receptor 6PGD PF00393.19 CBK19986.2 - 1.7e-49 168.7 0.0 2.3e-49 168.3 0.0 1.1 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.15 CBK19986.2 - 2.7e-18 66.6 0.0 4.6e-18 65.9 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase EF-hand_7 PF13499.6 CBK19987.2 - 9.5e-07 29.2 0.1 0.029 14.8 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 CBK19987.2 - 0.0054 16.6 2.7 1.6 8.9 0.1 2.4 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.32 CBK19987.2 - 0.014 14.9 2.1 0.43 10.2 0.1 2.3 2 0 0 2 2 2 0 EF hand EF-hand_5 PF13202.6 CBK19987.2 - 0.038 13.5 0.3 0.038 13.5 0.3 1.9 2 0 0 2 2 2 0 EF hand EssA PF10661.9 CBK19987.2 - 0.047 13.5 0.4 0.063 13.1 0.4 1.2 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein EssA Fib_alpha PF08702.10 CBK19988.2 - 0.0067 16.6 11.3 0.0067 16.6 11.3 5.5 3 1 1 5 5 5 2 Fibrinogen alpha/beta chain family bMG6 PF17962.1 CBK19988.2 - 0.016 15.3 3.9 0.038 14.1 0.3 3.2 2 0 0 2 2 2 0 Bacterial macroglobulin domain 6 PRELI PF04707.14 CBK19989.2 - 5e-29 101.1 0.0 5.8e-29 100.9 0.0 1.0 1 0 0 1 1 1 1 PRELI-like family PRELI PF04707.14 CBK19990.2 - 3.5e-24 85.4 0.1 4.2e-24 85.2 0.1 1.0 1 0 0 1 1 1 1 PRELI-like family EF-hand_1 PF00036.32 CBK19991.2 - 4.3e-35 116.6 11.7 1.5e-08 33.5 0.1 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 CBK19991.2 - 3.4e-30 104.3 8.3 1.2e-14 54.5 0.9 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 CBK19991.2 - 1.3e-27 94.1 11.8 2.4e-07 30.0 0.2 4.4 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.6 CBK19991.2 - 2.2e-27 92.6 5.5 4.8e-08 32.3 0.0 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 CBK19991.2 - 6.8e-24 83.5 9.0 4.7e-12 45.6 0.7 3.2 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_9 PF14658.6 CBK19991.2 - 2.1e-14 53.6 0.6 1.1e-07 32.1 0.1 2.1 2 0 0 2 2 2 2 EF-hand domain SPARC_Ca_bdg PF10591.9 CBK19991.2 - 4.4e-13 49.5 1.6 2.5e-06 27.8 0.1 2.2 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_11 PF08976.11 CBK19991.2 - 4.9e-11 43.4 0.7 0.0002 22.2 0.1 2.2 1 1 1 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 CBK19991.2 - 6.5e-08 32.5 5.8 0.0017 18.3 0.7 2.4 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand Dockerin_1 PF00404.18 CBK19991.2 - 6.9e-07 29.4 5.9 0.00011 22.3 0.6 3.3 2 1 1 3 3 3 2 Dockerin type I domain UPF0154 PF03672.13 CBK19991.2 - 2.6e-06 27.4 0.0 0.004 17.1 0.0 2.4 2 0 0 2 2 2 2 Uncharacterised protein family (UPF0154) Caleosin PF05042.13 CBK19991.2 - 6.7e-05 22.9 0.6 0.47 10.4 0.0 3.3 1 1 2 3 3 3 2 Caleosin related protein TerB PF05099.13 CBK19991.2 - 0.00016 21.7 0.4 0.061 13.3 0.1 2.3 1 1 1 2 2 2 1 Tellurite resistance protein TerB MotA_activ PF09114.10 CBK19991.2 - 0.00074 19.6 0.1 0.0023 18.0 0.0 1.8 1 1 1 2 2 2 1 Transcription factor MotA, activation domain SurA_N_2 PF13623.6 CBK19991.2 - 0.0043 16.9 4.8 0.0049 16.7 0.8 2.2 1 1 0 2 2 2 1 SurA N-terminal domain RNA_pol_Rpb4 PF03874.16 CBK19991.2 - 0.011 16.1 0.9 5.8 7.3 0.1 2.3 1 1 1 2 2 2 0 RNA polymerase Rpb4 DUF2666 PF10869.8 CBK19991.2 - 0.015 15.5 1.5 0.071 13.3 0.3 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2666) Syntaxin PF00804.25 CBK19991.2 - 0.015 14.9 1.2 0.81 9.3 0.2 2.2 1 1 0 2 2 2 0 Syntaxin EFhand_Ca_insen PF08726.10 CBK19991.2 - 0.018 15.1 0.7 0.21 11.7 0.0 2.4 2 0 0 2 2 2 0 Ca2+ insensitive EF hand UBA_6 PF18039.1 CBK19991.2 - 0.028 14.3 0.0 9.5 6.2 0.0 2.4 2 0 0 2 2 2 0 UBA-like domain OB_RNB PF08206.11 CBK19991.2 - 0.028 14.1 0.1 2.8 7.7 0.0 2.5 2 0 0 2 2 2 0 Ribonuclease B OB domain DUF5580 PF17743.1 CBK19991.2 - 0.048 12.2 0.0 0.083 11.4 0.0 1.3 1 1 0 1 1 1 0 Family of unknown function (DUF5580) Adenine_glyco PF03352.13 CBK19991.2 - 0.06 13.1 0.8 2.9 7.6 0.1 2.1 1 1 1 2 2 2 0 Methyladenine glycosylase SurA_N_3 PF13624.6 CBK19991.2 - 0.062 13.1 3.2 0.11 12.3 0.7 2.0 1 1 1 2 2 2 0 SurA N-terminal domain DUF1007 PF06226.13 CBK19991.2 - 0.084 12.9 0.9 2.7 7.9 0.2 2.6 1 1 2 3 3 3 0 Protein of unknown function (DUF1007) SCO1-SenC PF02630.14 CBK19991.2 - 0.15 12.0 1.6 0.36 10.8 0.5 2.1 1 1 1 2 2 2 0 SCO1/SenC RloB PF13707.6 CBK19991.2 - 1.2 9.3 5.2 9.5 6.4 0.9 2.2 1 1 1 2 2 2 0 RloB-like protein Ribosomal_L36e PF01158.18 CBK19992.2 - 1.7e-27 95.5 7.8 1.9e-27 95.3 7.8 1.0 1 0 0 1 1 1 1 Ribosomal protein L36e Dak2 PF02734.17 CBK19992.2 - 0.043 13.7 0.2 0.047 13.6 0.2 1.1 1 0 0 1 1 1 0 DAK2 domain D5_N PF08706.11 CBK19992.2 - 0.11 12.8 2.0 0.12 12.6 2.0 1.1 1 0 0 1 1 1 0 D5 N terminal like Ribosomal_L13e PF01294.18 CBK19993.2 - 7.8e-36 123.6 0.1 2.3e-35 122.1 0.1 1.7 1 1 0 1 1 1 1 Ribosomal protein L13e SecE PF00584.20 CBK19994.2 - 1.5e-15 56.9 0.0 1.6e-15 56.7 0.0 1.0 1 0 0 1 1 1 1 SecE/Sec61-gamma subunits of protein translocation complex Acetyltransf_10 PF13673.7 CBK19995.2 - 1.7e-15 57.1 0.0 2e-15 56.8 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 CBK19995.2 - 3.5e-08 33.7 0.0 6.4e-08 32.8 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 CBK19995.2 - 5.5e-08 33.1 0.1 8.2e-08 32.6 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 CBK19995.2 - 0.0054 16.8 0.0 0.22 11.6 0.0 2.2 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain AstA PF04958.12 CBK19995.2 - 0.06 11.9 0.0 1.5 7.2 0.0 2.0 1 1 1 2 2 2 0 Arginine N-succinyltransferase beta subunit Oxygenase-NA PF09859.9 CBK19997.2 - 0.11 12.0 0.3 0.26 10.8 0.3 1.6 1 1 0 1 1 1 0 Oxygenase, catalysing oxidative methylation of damaged DNA NIF3 PF01784.18 CBK19998.2 - 1.7e-52 178.5 0.0 2e-52 178.3 0.0 1.0 1 0 0 1 1 1 1 NIF3 (NGG1p interacting factor 3) OTU PF02338.19 CBK19999.2 - 2.1e-09 37.9 0.0 2.9e-09 37.5 0.0 1.2 1 0 0 1 1 1 1 OTU-like cysteine protease Peptidase_C65 PF10275.9 CBK19999.2 - 0.00079 18.9 0.3 0.012 15.0 0.3 2.1 1 1 0 1 1 1 1 Peptidase C65 Otubain Adaptin_N PF01602.20 CBK20000.2 - 4.2e-76 256.6 12.2 4.2e-76 256.6 12.2 1.7 2 0 0 2 2 2 1 Adaptin N terminal region Cnd1 PF12717.7 CBK20000.2 - 2.1e-13 50.7 5.9 2.6e-12 47.1 0.9 2.5 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 CBK20000.2 - 7e-06 25.9 5.7 0.034 14.4 0.1 5.4 6 1 1 7 7 5 1 HEAT repeat Vac14_Fab1_bd PF12755.7 CBK20000.2 - 0.00027 21.5 1.1 0.15 12.7 0.1 3.7 3 1 0 3 3 3 1 Vacuolar 14 Fab1-binding region HEAT_2 PF13646.6 CBK20000.2 - 0.00041 20.7 2.5 0.27 11.7 0.1 4.1 3 1 1 4 4 4 2 HEAT repeats HEAT_EZ PF13513.6 CBK20000.2 - 0.0016 18.9 0.9 0.54 10.8 0.0 4.3 4 1 1 5 5 4 1 HEAT-like repeat RTP1_C1 PF10363.9 CBK20000.2 - 0.0031 17.7 4.0 0.0098 16.1 0.3 3.5 3 1 0 4 4 4 1 Required for nuclear transport of RNA pol II C-terminus 1 Nipped-B_C PF12830.7 CBK20000.2 - 0.0035 17.3 0.2 0.026 14.4 0.1 2.2 2 0 0 2 2 2 1 Sister chromatid cohesion C-terminus API5 PF05918.11 CBK20000.2 - 0.0038 16.1 0.9 0.0038 16.1 0.9 2.3 2 1 0 2 2 1 1 Apoptosis inhibitory protein 5 (API5) Proteasom_PSMB PF10508.9 CBK20000.2 - 0.049 12.1 0.1 0.049 12.1 0.1 2.9 3 1 0 3 3 3 0 Proteasome non-ATPase 26S subunit Lbh PF15317.6 CBK20000.2 - 0.1 13.4 4.4 0.28 12.0 4.4 1.7 1 0 0 1 1 1 0 Cardiac transcription factor regulator, Developmental protein HEAT_UF PF18817.1 CBK20000.2 - 0.11 12.8 1.2 7.7 6.9 0.0 3.6 3 1 1 4 4 4 0 Repeat of uncharacterized protein PH0542 RIX1 PF08167.12 CBK20000.2 - 0.13 12.0 0.7 5.4 6.7 0.1 3.7 2 1 1 3 3 3 0 rRNA processing/ribosome biogenesis Arm PF00514.23 CBK20000.2 - 0.17 12.0 0.2 2.7 8.1 0.1 3.2 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat Histone PF00125.24 CBK20002.2 - 6.7e-53 178.5 2.8 7.5e-53 178.4 2.8 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 CBK20002.2 - 0.00011 22.5 0.1 0.00015 22.0 0.1 1.3 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 CBK20002.2 - 0.0005 20.2 0.1 0.00098 19.2 0.1 1.5 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold PAF PF15715.5 CBK20002.2 - 0.0011 19.6 0.9 0.0013 19.4 0.9 1.1 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CBFD_NFYB_HMF PF00808.23 CBK20002.2 - 0.019 15.2 0.0 0.039 14.2 0.0 1.5 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-T_C PF15511.6 CBK20003.2 - 2.6e-08 34.0 0.1 3.2e-08 33.7 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TAF PF02969.17 CBK20003.2 - 5.2e-05 23.3 0.1 8.2e-05 22.7 0.1 1.5 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) Histone PF00125.24 CBK20003.2 - 6.4e-05 23.3 0.1 9.8e-05 22.7 0.1 1.4 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 CBK20003.2 - 0.00022 21.5 0.1 0.0003 21.1 0.1 1.4 1 1 0 1 1 1 1 CENP-S protein CBFD_NFYB_HMF PF00808.23 CBK20003.2 - 0.00093 19.4 0.1 0.0017 18.6 0.0 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 CBK20003.2 - 0.01 15.9 0.0 0.012 15.7 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 CBK20003.2 - 0.025 14.6 0.0 0.036 14.1 0.0 1.2 1 0 0 1 1 1 0 Bromodomain associated CLPTM1 PF05602.12 CBK20004.2 - 4.3e-129 431.3 5.0 5.4e-129 431.0 5.0 1.1 1 0 0 1 1 1 1 Cleft lip and palate transmembrane protein 1 (CLPTM1) PQ-loop PF04193.14 CBK20004.2 - 0.00023 20.9 5.0 0.088 12.6 0.9 2.7 2 0 0 2 2 2 2 PQ loop repeat Glyco_transf_49 PF13896.6 CBK20005.2 - 3.1e-06 26.8 0.2 3.3e-06 26.7 0.2 1.2 1 1 0 1 1 1 1 Glycosyl-transferase for dystroglycan zf-ribbon_3 PF13248.6 CBK20006.2 - 0.11 12.0 0.9 0.23 10.9 0.3 1.9 2 0 0 2 2 2 0 zinc-ribbon domain Ribosomal_S27e PF01667.17 CBK20006.2 - 1.1 9.0 4.6 0.41 10.4 0.6 2.0 1 1 1 2 2 2 0 Ribosomal protein S27 Transketolase_N PF00456.21 CBK20007.2 - 3.3e-132 440.5 0.0 4.2e-132 440.2 0.0 1.1 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.24 CBK20007.2 - 1.7e-41 141.9 0.0 3.5e-41 140.8 0.0 1.6 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 CBK20007.2 - 1.6e-12 47.4 0.1 3.4e-12 46.3 0.1 1.6 1 0 0 1 1 1 1 Transketolase, C-terminal domain DXP_synthase_N PF13292.6 CBK20007.2 - 7.6e-05 22.1 0.0 0.00018 20.8 0.0 1.6 1 1 1 2 2 2 1 1-deoxy-D-xylulose-5-phosphate synthase E1_dh PF00676.20 CBK20007.2 - 0.035 13.0 0.0 0.079 11.9 0.0 1.6 1 0 0 1 1 1 0 Dehydrogenase E1 component Kelch_1 PF01344.25 CBK20007.2 - 0.19 11.3 2.6 32 4.2 0.0 3.4 3 0 0 3 3 3 0 Kelch motif Choline_kinase PF01633.20 CBK20008.2 - 3.6e-36 124.7 0.0 5.2e-36 124.2 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.23 CBK20008.2 - 1.1e-07 32.0 0.0 1.7e-07 31.4 0.0 1.3 1 1 0 1 1 1 1 Phosphotransferase enzyme family Pkinase PF00069.25 CBK20009.2 - 1.8e-73 247.1 0.0 2.1e-73 247.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBK20009.2 - 3.1e-30 105.3 0.0 4e-30 105.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 CBK20009.2 - 0.0012 17.9 0.1 0.0027 16.7 0.0 1.6 1 1 1 2 2 2 1 Haspin like kinase domain Kdo PF06293.14 CBK20009.2 - 0.013 14.9 0.1 0.02 14.2 0.1 1.4 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CBK20009.2 - 0.02 14.8 0.0 0.032 14.2 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family NDK PF00334.19 CBK20010.2 - 3.6e-56 188.9 0.0 4.1e-56 188.7 0.0 1.0 1 0 0 1 1 1 1 Nucleoside diphosphate kinase OST-HTH PF12872.7 CBK20010.2 - 0.16 11.8 0.0 0.48 10.3 0.0 1.7 2 0 0 2 2 2 0 OST-HTH/LOTUS domain LNS2 PF08235.13 CBK20011.2 - 5.3e-67 225.6 0.0 6.9e-67 225.2 0.0 1.1 1 0 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) tRNA_bind PF01588.20 CBK20012.2 - 6.6e-28 96.7 0.0 2.9e-27 94.6 0.0 2.0 2 0 0 2 2 2 1 Putative tRNA binding domain zf-C2H2_2 PF12756.7 CBK20013.2 - 1.9e-21 76.3 1.9 5e-21 74.9 1.9 1.6 1 1 0 1 1 1 1 C2H2 type zinc-finger (2 copies) CLP1_P PF16575.5 CBK20014.2 - 8.2e-35 120.3 0.0 1.3e-34 119.7 0.0 1.3 1 0 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop Clp1 PF06807.14 CBK20014.2 - 4.4e-18 65.8 0.0 8e-18 65.0 0.0 1.4 1 0 0 1 1 1 1 Pre-mRNA cleavage complex II protein Clp1 CLP1_N PF16573.5 CBK20014.2 - 1.7e-14 53.8 0.0 4.3e-14 52.5 0.0 1.7 2 0 0 2 2 2 1 N-terminal beta-sandwich domain of polyadenylation factor E1_FCCH PF16190.5 CBK20014.2 - 0.18 12.0 0.0 0.88 9.8 0.0 2.0 2 0 0 2 2 2 0 Ubiquitin-activating enzyme E1 FCCH domain Metallophos PF00149.28 CBK20015.2 - 2.2e-35 123.0 0.0 2.7e-35 122.7 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 CBK20015.2 - 6e-11 42.6 1.2 1.2e-10 41.6 1.2 1.5 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain Metallophos_2 PF12850.7 CBK20015.2 - 0.088 13.0 0.0 0.16 12.2 0.0 1.4 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain 60KD_IMP PF02096.20 CBK20016.2 - 6.7e-35 120.4 0.0 1.3e-34 119.5 0.0 1.5 1 0 0 1 1 1 1 60Kd inner membrane protein Glutaredoxin PF00462.24 CBK20017.2 - 4.7e-13 49.1 0.0 7.1e-13 48.6 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin Rubredoxin_C PF18267.1 CBK20017.2 - 0.02 14.8 0.0 0.025 14.5 0.0 1.1 1 0 0 1 1 1 0 Rubredoxin NAD+ reductase C-terminal domain EST1_DNA_bind PF10373.9 CBK20018.2 - 2.9e-20 72.9 3.1 5.2e-20 72.1 3.1 1.4 1 0 0 1 1 1 1 Est1 DNA/RNA binding domain TPR_17 PF13431.6 CBK20018.2 - 3.3e-05 24.0 0.1 0.00017 21.7 0.1 2.3 1 0 0 1 1 1 1 Tetratricopeptide repeat EST1 PF10374.9 CBK20018.2 - 0.0046 17.6 9.0 1.2 9.8 1.6 3.9 3 1 1 4 4 4 2 Telomerase activating protein Est1 TPR_11 PF13414.6 CBK20018.2 - 0.14 11.8 0.0 0.34 10.6 0.0 1.6 1 0 0 1 1 1 0 TPR repeat Usp PF00582.26 CBK20019.2 - 1.3e-14 54.9 0.0 4.4e-14 53.2 0.0 1.8 1 1 0 1 1 1 1 Universal stress protein family Aminotran_1_2 PF00155.21 CBK20020.2 - 1.3e-58 199.0 0.0 1.5e-58 198.7 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II HATPase_c_5 PF14501.6 CBK20020.2 - 0.0065 16.4 0.0 0.013 15.4 0.0 1.5 1 0 0 1 1 1 1 GHKL domain Romo1 PF10247.9 CBK20020.2 - 0.023 15.1 0.2 0.051 13.9 0.2 1.5 1 0 0 1 1 1 0 Reactive mitochondrial oxygen species modulator 1 Ribosomal_L5_C PF00673.21 CBK20021.2 - 4.4e-20 71.6 0.0 7.7e-20 70.9 0.0 1.4 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.19 CBK20021.2 - 1e-19 70.6 0.2 1.9e-19 69.7 0.2 1.5 1 0 0 1 1 1 1 Ribosomal protein L5 HTH_ABP1_N PF18107.1 CBK20021.2 - 0.037 13.8 0.4 0.15 11.8 0.1 2.0 2 0 0 2 2 2 0 Fission yeast centromere protein N-terminal domain Peptidase_A22B PF04258.13 CBK20022.2 - 5.9e-28 98.2 22.3 9.7e-28 97.5 22.3 1.3 1 1 0 1 1 1 1 Signal peptide peptidase CoxIIa PF08113.11 CBK20022.2 - 0.29 11.0 4.8 1.4 8.8 4.8 2.2 1 0 0 1 1 1 0 Cytochrome c oxidase subunit IIa family Tubulin PF00091.25 CBK20023.2 - 1.5e-68 230.9 0.0 2.8e-68 230.0 0.0 1.5 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 CBK20023.2 - 1.4e-38 131.9 0.0 2.3e-38 131.2 0.0 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 CBK20023.2 - 1.5e-07 31.7 0.0 3.4e-07 30.6 0.0 1.6 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_2 PF13809.6 CBK20023.2 - 0.028 13.6 0.1 0.11 11.7 0.0 1.9 2 0 0 2 2 2 0 Tubulin like Tubulin_3 PF14881.6 CBK20023.2 - 0.03 14.0 0.0 0.06 13.0 0.0 1.5 1 0 0 1 1 1 0 Tubulin domain Glyco_hydro_18 PF00704.28 CBK20024.2 - 2.4e-84 283.8 3.7 3.3e-84 283.3 3.7 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 DUF3149 PF11346.8 CBK20024.2 - 0.83 9.3 4.8 1.7 8.3 4.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3149) DUF563 PF04577.14 CBK20025.2 - 5.2e-16 59.4 0.1 7e-16 59.0 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF563) Proteasome PF00227.26 CBK20026.2 - 7.7e-32 110.3 0.1 9.9e-32 110.0 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Metallophos PF00149.28 CBK20027.2 - 6.8e-35 121.4 0.0 8.8e-35 121.1 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 CBK20027.2 - 0.0015 18.9 0.6 0.0037 17.7 0.6 1.6 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain Dimer_Tnp_hAT PF05699.14 CBK20028.2 - 0.00061 19.5 0.1 0.0014 18.3 0.1 1.7 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DUF659 PF04937.15 CBK20028.2 - 0.0058 16.5 0.3 0.013 15.3 0.3 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) zinc_ribbon_12 PF11331.8 CBK20028.2 - 0.23 11.3 2.1 0.38 10.6 0.9 2.0 2 0 0 2 2 2 0 Probable zinc-ribbon domain Mito_carr PF00153.27 CBK20029.2 - 6.6e-62 205.5 8.1 1.3e-22 79.5 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein CytB6-F_Fe-S PF08802.10 CBK20029.2 - 0.8 9.8 8.7 1.8 8.7 0.0 3.3 3 0 0 3 3 3 0 Cytochrome B6-F complex Fe-S subunit ER_lumen_recept PF00810.18 CBK20030.2 - 8.7e-35 120.7 7.4 8.7e-35 120.7 7.4 2.5 3 0 0 3 3 3 1 ER lumen protein retaining receptor DUF3981 PF13139.6 CBK20030.2 - 2.5 8.5 7.1 1.6 9.2 0.0 3.2 1 1 1 3 3 3 0 Domain of unknown function (DUF3981) FH2 PF02181.23 CBK20031.2 - 3e-75 253.7 0.0 3.8e-75 253.3 0.0 1.1 1 0 0 1 1 1 1 Formin Homology 2 Domain IMD PF08397.11 CBK20031.2 - 0.13 11.6 0.3 0.47 9.8 0.0 1.9 2 0 0 2 2 2 0 IRSp53/MIM homology domain Opi1 PF08618.10 CBK20031.2 - 0.29 10.3 6.8 1.2 8.4 0.7 2.2 2 0 0 2 2 2 0 Transcription factor Opi1 CCDC53 PF10152.9 CBK20031.2 - 0.53 10.7 17.4 0.39 11.1 0.3 3.4 3 0 0 3 3 3 0 Subunit CCDC53 of WASH complex Acyltransferase PF01553.21 CBK20032.2 - 1.6e-10 40.7 0.0 2.2e-10 40.3 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase NARP1 PF12569.8 CBK20033.2 - 1.1e-90 305.0 11.1 7.7e-90 302.2 3.2 2.6 2 1 0 2 2 2 2 NMDA receptor-regulated protein 1 TPR_14 PF13428.6 CBK20033.2 - 2.9e-06 27.6 1.4 4.2 8.5 0.1 6.6 7 2 2 9 9 7 2 Tetratricopeptide repeat TPR_16 PF13432.6 CBK20033.2 - 6.9e-05 23.4 5.7 0.093 13.4 0.1 5.0 5 1 0 5 5 5 1 Tetratricopeptide repeat TPR_19 PF14559.6 CBK20033.2 - 0.00022 21.7 10.9 0.96 10.0 0.1 5.2 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_12 PF13424.6 CBK20033.2 - 0.0012 19.0 6.5 2.9 8.2 0.0 5.0 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.28 CBK20033.2 - 0.0047 16.7 12.7 0.062 13.1 0.1 5.9 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_8 PF13181.6 CBK20033.2 - 0.013 15.7 11.2 0.43 10.9 0.1 5.6 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_17 PF13431.6 CBK20033.2 - 0.029 14.8 10.1 1.5 9.4 0.1 4.9 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_2 PF07719.17 CBK20033.2 - 0.038 14.1 21.6 0.19 11.9 0.3 7.6 9 0 0 9 9 9 0 Tetratricopeptide repeat TPR_6 PF13174.6 CBK20033.2 - 0.1 13.2 6.6 50 4.8 0.0 5.9 5 0 0 5 5 5 0 Tetratricopeptide repeat AF-4 PF05110.13 CBK20033.2 - 2.2 6.2 8.9 3.2 5.7 8.9 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein GTP_EFTU PF00009.27 CBK20034.2 - 3.6e-59 199.6 0.1 6.8e-59 198.7 0.1 1.5 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 CBK20034.2 - 2.4e-38 130.6 0.1 1.4e-37 128.2 0.0 2.4 3 0 0 3 3 3 1 Elongation factor G, domain IV EFG_II PF14492.6 CBK20034.2 - 9.5e-30 102.5 0.0 2.5e-29 101.2 0.0 1.8 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.24 CBK20034.2 - 1.9e-27 95.1 0.1 4.7e-27 93.9 0.1 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 CBK20034.2 - 6.4e-12 45.7 0.1 3.1e-11 43.5 0.0 2.3 3 0 0 3 3 3 1 Elongation factor Tu domain 2 RF3_C PF16658.5 CBK20034.2 - 7.2e-05 22.6 0.0 0.00018 21.3 0.0 1.6 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain MMR_HSR1 PF01926.23 CBK20034.2 - 0.0037 17.3 0.0 0.0099 16.0 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.16 CBK20034.2 - 0.023 14.0 0.1 0.088 12.1 0.0 1.9 2 0 0 2 2 2 0 AIG1 family SBDS_C PF09377.10 CBK20034.2 - 0.05 13.6 0.0 0.34 10.9 0.0 2.3 2 0 0 2 2 2 0 SBDS protein C-terminal domain NNMT_PNMT_TEMT PF01234.17 CBK20035.2 - 0.0029 16.8 0.0 0.0077 15.4 0.0 1.6 2 0 0 2 2 2 1 NNMT/PNMT/TEMT family Methyltransf_31 PF13847.6 CBK20035.2 - 0.01 15.6 0.0 0.01 15.6 0.0 1.1 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.6 CBK20035.2 - 0.021 14.7 0.0 0.024 14.5 0.0 1.1 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_8 PF05148.15 CBK20035.2 - 0.024 14.5 0.0 0.029 14.2 0.0 1.1 1 0 0 1 1 1 0 Hypothetical methyltransferase Methyltransf_11 PF08241.12 CBK20035.2 - 0.037 14.7 0.0 0.064 13.9 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Ubie_methyltran PF01209.18 CBK20035.2 - 0.042 13.2 0.0 0.051 12.9 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family LRR_8 PF13855.6 CBK20036.2 - 8.3e-06 25.5 1.5 0.00025 20.7 0.2 3.0 2 1 1 3 3 3 1 Leucine rich repeat LRR_4 PF12799.7 CBK20036.2 - 0.0015 18.8 2.2 3.2 8.3 0.3 3.9 2 1 2 4 4 4 2 Leucine Rich repeats (2 copies) Pax7 PF12360.8 CBK20036.2 - 0.053 13.7 0.1 0.2 11.8 0.1 2.0 1 0 0 1 1 1 0 Paired box protein 7 LRR_1 PF00560.33 CBK20036.2 - 0.18 12.5 1.6 42 5.3 0.0 4.4 3 1 0 3 3 3 0 Leucine Rich Repeat DJ-1_PfpI PF01965.24 CBK20037.2 - 1.2e-44 152.0 0.3 1.4e-44 151.8 0.3 1.0 1 0 0 1 1 1 1 DJ-1/PfpI family ThiJ_like PF17124.5 CBK20037.2 - 0.033 13.9 0.0 0.044 13.5 0.0 1.3 1 0 0 1 1 1 0 ThiJ/PfpI family-like GATase_3 PF07685.14 CBK20037.2 - 0.078 12.6 0.0 0.18 11.3 0.0 1.6 2 0 0 2 2 2 0 CobB/CobQ-like glutamine amidotransferase domain TP_methylase PF00590.20 CBK20038.2 - 5.7e-21 75.4 0.0 7.6e-21 75.0 0.0 1.2 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases MMS1_N PF10433.9 CBK20038.2 - 0.044 12.4 0.0 0.069 11.8 0.0 1.2 1 0 0 1 1 1 0 Mono-functional DNA-alkylating methyl methanesulfonate N-term Peptidase_M1_N PF17900.1 CBK20041.2 - 0.00055 20.2 0.0 0.0013 19.0 0.0 1.6 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain Peptidase_M1 PF01433.20 CBK20041.2 - 0.0007 19.2 0.0 0.0011 18.6 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M1 domain Ank_2 PF12796.7 CBK20042.2 - 9.4e-22 77.4 7.6 2.4e-12 47.3 0.5 3.4 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CBK20042.2 - 2.3e-21 75.9 3.1 1.1e-09 38.6 0.0 4.0 4 1 0 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 CBK20042.2 - 3.6e-14 51.5 7.9 0.00059 20.1 0.1 5.8 6 0 0 6 6 6 3 Ankyrin repeat Ank_5 PF13857.6 CBK20042.2 - 4.9e-14 52.2 8.3 0.00047 20.4 0.3 5.7 3 2 2 5 5 5 5 Ankyrin repeats (many copies) Ank PF00023.30 CBK20042.2 - 2.3e-10 40.4 4.3 0.014 15.8 0.7 4.3 4 0 0 4 4 4 3 Ankyrin repeat Peptidase_C98 PF15499.6 CBK20043.2 - 0.047 13.1 0.5 0.095 12.2 0.5 1.5 1 0 0 1 1 1 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase DUF2935 PF11155.8 CBK20043.2 - 0.8 10.0 4.0 18 5.7 1.1 3.6 2 1 1 3 3 3 0 Domain of unknown function (DUF2935) Syja_N PF02383.18 CBK20044.2 - 9.4e-58 196.0 0.0 1.1e-57 195.8 0.0 1.0 1 0 0 1 1 1 1 SacI homology domain HTH_29 PF13551.6 CBK20044.2 - 0.076 13.0 0.1 0.19 11.8 0.1 1.5 2 0 0 2 2 2 0 Winged helix-turn helix Lyase_1 PF00206.20 CBK20045.2 - 7.7e-88 294.9 0.0 9.7e-88 294.5 0.0 1.1 1 0 0 1 1 1 1 Lyase FumaraseC_C PF10415.9 CBK20045.2 - 3.2e-17 62.7 0.1 1.4e-16 60.6 0.0 2.2 2 0 0 2 2 2 1 Fumarase C C-terminus SspK PF08176.12 CBK20046.2 - 0.11 12.8 0.2 0.17 12.2 0.2 1.3 1 0 0 1 1 1 0 Small acid-soluble spore protein K family Aa_trans PF01490.18 CBK20047.2 - 1.6e-21 76.5 16.9 1.7e-21 76.4 16.9 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein SdpI PF13630.6 CBK20047.2 - 0.14 12.3 0.4 0.14 12.3 0.4 3.4 1 1 1 2 2 2 0 SdpI/YhfL protein family Sec23_trunk PF04811.15 CBK20049.2 - 1.1e-20 74.3 0.0 1.8e-20 73.6 0.0 1.3 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.15 CBK20049.2 - 4.9e-12 45.6 0.1 1e-11 44.6 0.1 1.6 1 0 0 1 1 1 1 Sec23/Sec24 helical domain zf-Sec23_Sec24 PF04810.15 CBK20049.2 - 1.1e-11 44.6 2.3 2.8e-11 43.3 2.3 1.8 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Sec23_BS PF08033.12 CBK20049.2 - 5.4e-09 36.7 0.0 1.2e-08 35.6 0.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain DDE_Tnp_4 PF13359.6 CBK20051.2 - 1.5e-10 40.9 0.0 2.6e-10 40.2 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease Tsg PF04668.12 CBK20051.2 - 0.048 14.3 0.3 0.12 13.0 0.3 1.8 1 0 0 1 1 1 0 Twisted gastrulation (Tsg) protein conserved region NADH-u_ox-rdase PF10785.9 CBK20052.2 - 4.9e-10 40.0 0.1 5.5e-10 39.8 0.1 1.0 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit MOZ_SAS PF01853.18 CBK20055.2 - 9.9e-79 263.2 2.5 1.4e-78 262.7 2.5 1.2 1 0 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 CBK20055.2 - 5.4e-20 70.8 2.6 5.4e-20 70.8 2.6 1.9 2 0 0 2 2 2 1 MYST family zinc finger domain Acetyltransf_7 PF13508.7 CBK20055.2 - 0.0023 18.3 0.0 0.0049 17.3 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain zf-C2H2_4 PF13894.6 CBK20055.2 - 0.22 12.4 3.7 0.71 10.9 3.7 2.0 1 0 0 1 1 1 0 C2H2-type zinc finger SNAP PF14938.6 CBK20056.2 - 9e-16 58.1 12.7 4.4e-13 49.3 12.7 3.2 1 1 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_12 PF13424.6 CBK20056.2 - 1.6e-07 31.5 10.3 0.0059 16.9 1.6 4.1 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 CBK20056.2 - 0.00026 20.9 17.6 0.0024 17.9 1.7 6.2 7 1 1 8 8 7 1 Tetratricopeptide repeat TPR_1 PF00515.28 CBK20056.2 - 0.007 16.1 2.1 0.007 16.1 2.1 4.9 5 1 1 6 6 6 1 Tetratricopeptide repeat TPR_8 PF13181.6 CBK20056.2 - 0.024 14.8 6.0 2 8.8 2.4 5.0 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_16 PF13432.6 CBK20056.2 - 0.13 13.0 6.5 2.1 9.1 0.4 4.2 3 2 0 4 4 3 0 Tetratricopeptide repeat PPR PF01535.20 CBK20056.2 - 0.18 12.1 0.2 9.7 6.7 0.0 3.7 3 0 0 3 3 3 0 PPR repeat TPR_7 PF13176.6 CBK20056.2 - 0.21 11.7 5.4 6.5 7.0 1.1 4.1 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_11 PF13414.6 CBK20056.2 - 0.97 9.2 4.2 1 9.1 2.3 2.1 2 0 0 2 2 2 0 TPR repeat TPR_14 PF13428.6 CBK20056.2 - 1.5 9.8 14.0 12 7.0 0.0 5.3 7 0 0 7 7 6 0 Tetratricopeptide repeat TPR_10 PF13374.6 CBK20056.2 - 1.7 8.6 5.9 40 4.2 0.6 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat RecQ_Zn_bind PF16124.5 CBK20057.2 - 0.0035 18.0 0.2 0.0037 18.0 0.2 1.2 1 0 0 1 1 1 1 RecQ zinc-binding LSM PF01423.22 CBK20058.2 - 5.9e-15 54.7 0.3 1.2e-14 53.7 0.3 1.6 1 0 0 1 1 1 1 LSM domain PBP_sp32 PF07222.12 CBK20058.2 - 0.065 12.7 1.2 0.13 11.7 1.2 1.4 1 0 0 1 1 1 0 Proacrosin binding protein sp32 Astro_capsid_p PF12226.8 CBK20058.2 - 0.16 11.1 5.9 0.28 10.3 5.9 1.3 1 0 0 1 1 1 0 Turkey astrovirus capsid protein CENP-B_dimeris PF09026.10 CBK20058.2 - 0.71 10.3 6.5 1.7 9.1 6.5 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain SKIP_SNW PF02731.15 CBK20059.2 - 1.7e-61 206.6 0.3 1.7e-61 206.6 0.3 2.6 2 0 0 2 2 2 1 SKIP/SNW domain Pkinase PF00069.25 CBK20060.2 - 1.7e-59 201.4 0.0 2.1e-59 201.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBK20060.2 - 3.6e-32 111.7 0.0 5.4e-32 111.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase PH PF00169.29 CBK20060.2 - 7.6e-06 26.4 0.0 1.4e-05 25.6 0.0 1.4 1 0 0 1 1 1 1 PH domain Pkinase_fungal PF17667.1 CBK20060.2 - 0.0021 16.9 0.1 0.038 12.8 0.0 2.0 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 CBK20060.2 - 0.0051 16.2 0.0 0.0076 15.6 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Nudix_N_2 PF14803.6 CBK20060.2 - 0.092 12.7 2.9 0.56 10.2 0.1 2.5 2 0 0 2 2 2 0 Nudix N-terminal APH PF01636.23 CBK20060.2 - 0.15 12.0 0.1 3.6 7.4 0.0 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family PH_9 PF15410.6 CBK20060.2 - 0.18 12.1 0.6 5.7 7.3 0.6 2.5 1 1 0 1 1 1 0 Pleckstrin homology domain Acetyltransf_1 PF00583.25 CBK20061.2 - 0.00042 20.5 0.0 0.00076 19.7 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.7 CBK20061.2 - 0.0075 16.4 0.0 0.011 15.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 CBK20061.2 - 0.01 16.5 0.0 0.017 15.8 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain UPF0227 PF05728.12 CBK20061.2 - 0.14 12.1 0.0 0.22 11.5 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) Bot1p PF12298.8 CBK20062.2 - 2.1e-05 24.8 0.1 2.1e-05 24.8 0.1 2.9 2 2 1 3 3 3 1 Eukaryotic mitochondrial regulator protein HTH_29 PF13551.6 CBK20062.2 - 0.013 15.6 0.0 0.79 9.8 0.1 2.7 2 0 0 2 2 2 0 Winged helix-turn helix HTH_23 PF13384.6 CBK20062.2 - 0.019 14.8 0.0 0.067 13.0 0.0 1.9 1 0 0 1 1 1 0 Homeodomain-like domain HTH_28 PF13518.6 CBK20062.2 - 0.025 14.7 0.0 0.13 12.4 0.0 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain Borrelia_P83 PF05262.11 CBK20062.2 - 1.2 7.5 11.6 2 6.8 11.6 1.3 1 0 0 1 1 1 0 Borrelia P83/100 protein Plasmodium_Vir PF05795.11 CBK20062.2 - 1.6 8.1 6.8 2.5 7.4 6.8 1.4 1 0 0 1 1 1 0 Plasmodium vivax Vir protein TRAP_alpha PF03896.16 CBK20062.2 - 1.7 7.7 0.0 1.7 7.7 0.0 3.0 2 1 0 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit DUF4407 PF14362.6 CBK20062.2 - 3 7.1 7.7 4.8 6.4 7.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Hydin_ADK PF17213.3 CBK20062.2 - 3 8.1 8.9 7.3 6.8 8.9 1.6 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain Presenilin PF01080.17 CBK20062.2 - 6.2 5.5 10.5 10 4.8 10.5 1.3 1 0 0 1 1 1 0 Presenilin THF_DHG_CYH_C PF02882.19 CBK20063.2 - 4.8e-71 237.3 1.0 7.1e-71 236.7 1.0 1.3 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.23 CBK20063.2 - 1.4e-40 138.2 0.5 2e-40 137.7 0.5 1.3 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain AlaDh_PNT_C PF01262.21 CBK20063.2 - 0.018 14.3 1.7 0.031 13.6 1.7 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain ANAPC4_WD40 PF12894.7 CBK20064.2 - 6.4e-10 39.2 0.5 2.3 8.6 0.2 5.1 3 1 2 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 CBK20064.2 - 0.0051 17.6 0.0 31 5.7 0.0 4.9 6 0 0 6 6 6 0 WD domain, G-beta repeat Nup160 PF11715.8 CBK20064.2 - 0.0075 15.0 0.1 2.1 6.9 0.0 2.2 2 0 0 2 2 2 2 Nucleoporin Nup120/160 DPPIV_N PF00930.21 CBK20064.2 - 0.17 10.6 0.0 1.3 7.7 0.0 2.0 1 1 1 2 2 2 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region WD40_like PF17005.5 CBK20064.2 - 0.18 11.1 0.2 19 4.5 0.0 2.8 2 1 1 3 3 3 0 WD40-like domain Coatomer_WDAD PF04053.14 CBK20064.2 - 0.23 10.5 0.1 1.9 7.5 0.0 2.1 2 0 0 2 2 2 0 Coatomer WD associated region HSP70 PF00012.20 CBK20065.2 - 9.4e-27 93.4 0.0 1.1e-25 90.0 0.0 1.9 1 1 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 CBK20065.2 - 0.016 14.0 0.6 0.04 12.7 0.6 1.7 1 1 0 1 1 1 0 MreB/Mbl protein StbA PF06406.11 CBK20065.2 - 0.11 11.7 0.1 0.27 10.4 0.0 1.7 2 0 0 2 2 2 0 StbA protein DnaJ_C PF01556.18 CBK20067.2 - 1.7e-36 125.6 0.0 2.6e-36 124.9 0.0 1.3 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 CBK20067.2 - 2.6e-21 75.5 0.3 4.4e-21 74.8 0.3 1.4 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 CBK20067.2 - 1.2e-14 54.4 21.0 3.3e-14 53.0 21.0 1.8 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 CBK20067.2 - 0.0006 19.7 12.1 0.14 12.1 2.6 2.6 2 0 0 2 2 2 2 Tryptophan RNA-binding attenuator protein inhibitory protein HypA PF01155.19 CBK20067.2 - 3.7 7.6 13.2 0.54 10.3 1.8 2.4 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA GDP_Man_Dehyd PF16363.5 CBK20068.2 - 2.2e-52 178.5 0.0 2.7e-52 178.2 0.0 1.0 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 CBK20068.2 - 3.4e-46 157.7 0.0 4.1e-46 157.4 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 CBK20068.2 - 2.4e-11 43.3 0.0 1.3e-09 37.6 0.0 2.8 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.19 CBK20068.2 - 3.7e-11 42.5 0.0 5.2e-11 42.1 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 CBK20068.2 - 8.4e-09 35.0 0.1 5.7e-08 32.3 0.1 2.1 1 1 0 1 1 1 1 Male sterility protein RmlD_sub_bind PF04321.17 CBK20068.2 - 8.3e-08 31.7 0.0 1.2e-07 31.2 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.6 CBK20068.2 - 1.4e-06 28.4 0.0 2.7e-06 27.4 0.0 1.5 1 0 0 1 1 1 1 NAD(P)H-binding adh_short PF00106.25 CBK20068.2 - 8.1e-06 25.4 0.0 1.3e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 CBK20068.2 - 0.00048 20.1 0.0 0.001 19.0 0.0 1.5 1 1 0 1 1 1 1 KR domain NmrA PF05368.13 CBK20068.2 - 0.023 14.3 0.0 0.08 12.5 0.0 1.8 2 0 0 2 2 2 0 NmrA-like family adh_short_C2 PF13561.6 CBK20068.2 - 0.038 13.5 0.0 0.07 12.7 0.0 1.4 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase Histone_H2A_C PF16211.5 CBK20069.2 - 3.3e-15 55.5 0.0 5.5e-15 54.8 0.0 1.4 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 CBK20069.2 - 2.4e-13 50.6 0.0 4e-13 49.8 0.0 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 CBK20069.2 - 1.4e-05 25.2 0.0 2e-05 24.8 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 CBK20070.2 - 4.5e-20 72.4 0.2 5.5e-20 72.1 0.2 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 CBK20070.2 - 1.8e-05 24.9 0.2 3.7e-05 23.9 0.0 1.5 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone ADH_zinc_N_2 PF13602.6 CBK20071.2 - 5.8e-11 43.6 0.0 2.6e-10 41.5 0.0 1.9 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 CBK20071.2 - 1.3e-09 37.9 0.3 3.6e-09 36.5 0.2 1.7 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 CBK20071.2 - 9.7e-09 35.3 0.0 1.8e-08 34.4 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase NAD_binding_10 PF13460.6 CBK20071.2 - 0.00048 20.1 0.0 0.00063 19.7 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding DNA_processg_A PF02481.15 CBK20071.2 - 0.098 11.9 0.1 0.16 11.2 0.1 1.2 1 0 0 1 1 1 0 DNA recombination-mediator protein A Glyco_hydro_18 PF00704.28 CBK20072.2 - 4.9e-84 282.7 3.2 6.4e-84 282.3 3.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 DUF3149 PF11346.8 CBK20072.2 - 0.0084 15.7 2.4 0.018 14.6 2.4 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3149) Tubulin PF00091.25 CBK20073.2 - 1.5e-68 230.9 0.0 2.8e-68 230.0 0.0 1.5 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 CBK20073.2 - 1.4e-38 131.9 0.0 2.3e-38 131.2 0.0 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 CBK20073.2 - 1.5e-07 31.7 0.0 3.4e-07 30.6 0.0 1.6 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_2 PF13809.6 CBK20073.2 - 0.028 13.6 0.1 0.11 11.7 0.0 1.9 2 0 0 2 2 2 0 Tubulin like Tubulin_3 PF14881.6 CBK20073.2 - 0.03 14.0 0.0 0.06 13.0 0.0 1.5 1 0 0 1 1 1 0 Tubulin domain MFS_1 PF07690.16 CBK20074.2 - 3e-21 75.7 71.4 2.4e-18 66.2 49.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 CBK20074.2 - 0.00041 19.0 15.0 0.00041 19.0 15.0 3.3 2 1 1 3 3 3 1 MFS/sugar transport protein UPF0640 PF15114.6 CBK20074.2 - 0.12 12.2 0.5 0.43 10.4 0.2 2.1 2 0 0 2 2 2 0 Uncharacterised protein family UPF0640 Nitroreductase PF00881.24 CBK20075.2 - 7.6e-24 84.7 0.0 2.7e-11 43.8 0.0 2.1 1 1 1 2 2 2 2 Nitroreductase family TM1586_NiRdase PF14512.6 CBK20075.2 - 4e-07 29.8 0.0 0.0045 16.6 0.0 2.1 2 0 0 2 2 2 2 Putative TM nitroreductase Nitroreductase PF00881.24 CBK20076.2 - 1.6e-06 28.3 0.0 2e-06 28.0 0.0 1.1 1 0 0 1 1 1 1 Nitroreductase family TM1586_NiRdase PF14512.6 CBK20076.2 - 0.18 11.3 0.0 0.2 11.2 0.0 1.0 1 0 0 1 1 1 0 Putative TM nitroreductase Proteasome PF00227.26 CBK20077.2 - 1e-53 181.7 0.4 1.5e-53 181.1 0.4 1.3 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 CBK20077.2 - 3.5e-11 42.6 0.1 6.4e-11 41.7 0.1 1.5 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature DUF1206 PF06724.11 CBK20077.2 - 0.04 14.0 0.1 0.14 12.2 0.1 2.0 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1206) DUF805 PF05656.14 CBK20077.2 - 1.1 9.7 11.2 0.18 12.2 6.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF805) MgtE PF01769.16 CBK20077.2 - 3.5 8.0 15.7 15 6.0 11.3 2.4 2 0 0 2 2 2 0 Divalent cation transporter DUF4013 PF13197.6 CBK20077.2 - 7.9 6.3 16.3 3.4 7.5 11.8 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4013) Methyltransf_7 PF03492.15 CBK20078.2 - 0.044 13.0 0.2 0.067 12.4 0.2 1.3 1 0 0 1 1 1 0 SAM dependent carboxyl methyltransferase Ribosomal_L38e PF01781.18 CBK20079.2 - 9e-31 105.8 4.2 1.3e-30 105.3 4.2 1.2 1 0 0 1 1 1 1 Ribosomal L38e protein family Laminin_II PF06009.12 CBK20079.2 - 0.096 12.7 1.1 0.14 12.2 0.5 1.6 1 1 1 2 2 2 0 Laminin Domain II DHO_dh PF01180.21 CBK20080.2 - 4.1e-50 170.7 0.0 5.4e-50 170.3 0.0 1.1 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase SURF2 PF05477.11 CBK20081.2 - 9.7e-32 110.5 0.6 1e-31 110.5 0.6 1.0 1 0 0 1 1 1 1 Surfeit locus protein 2 (SURF2) DUF1743 PF08489.11 CBK20081.2 - 0.0061 16.6 0.1 0.0077 16.3 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1743) DUF2870 PF11069.8 CBK20081.2 - 0.038 14.4 1.0 0.23 11.9 0.5 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2870) Mac PF12464.8 CBK20081.2 - 0.085 13.1 0.2 0.085 13.1 0.2 1.9 2 1 0 2 2 2 0 Maltose acetyltransferase LEDGF PF11467.8 CBK20081.2 - 0.13 11.9 5.0 0.33 10.6 0.6 2.1 2 0 0 2 2 2 0 Lens epithelium-derived growth factor (LEDGF) PHO4 PF01384.20 CBK20082.2 - 3.9e-115 384.5 27.0 5.4e-115 384.0 27.0 1.2 1 0 0 1 1 1 1 Phosphate transporter family DUF2048 PF09752.9 CBK20082.2 - 1.1e-61 209.0 0.0 2.1e-61 208.0 0.0 1.5 1 1 0 1 1 1 1 Abhydrolase domain containing 18 Abhydrolase_6 PF12697.7 CBK20082.2 - 6e-05 23.7 0.0 0.00013 22.7 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family He_PIG PF05345.12 CBK20083.2 - 2.1e-18 66.3 37.1 1.4e-05 25.2 1.8 6.5 5 0 0 5 5 5 5 Putative Ig domain PA14 PF07691.12 CBK20083.2 - 5.7e-17 61.9 0.4 1.7e-10 40.9 0.0 3.3 3 0 0 3 3 3 2 PA14 domain DUF11 PF01345.18 CBK20083.2 - 2.8e-05 24.3 4.3 0.43 10.9 0.0 6.4 6 1 1 7 7 7 1 Domain of unknown function DUF11 GLEYA PF10528.9 CBK20083.2 - 0.12 12.8 10.3 0.2 12.1 0.4 4.5 3 0 0 3 3 3 0 GLEYA domain Stevor PF17410.2 CBK20083.2 - 0.14 11.7 0.6 0.24 10.9 0.6 1.3 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame F5_F8_type_C PF00754.25 CBK20083.2 - 1 9.5 8.4 0.058 13.5 2.5 2.0 2 0 0 2 2 2 0 F5/8 type C domain PCI PF01399.27 CBK20085.2 - 0.013 15.9 2.1 0.018 15.6 0.1 2.2 2 1 0 2 2 2 0 PCI domain FSA_C PF10479.9 CBK20085.2 - 0.4 8.8 9.0 0.64 8.1 9.0 1.2 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus Herpes_capsid PF06112.11 CBK20085.2 - 1.7 8.7 11.4 3.9 7.5 11.4 1.6 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein Cyclin_N PF00134.23 CBK20086.2 - 0.00014 21.6 0.0 0.00022 20.9 0.0 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain Adenylsucc_synt PF00709.21 CBK20087.2 - 4.2e-167 556.3 0.0 4.8e-167 556.1 0.0 1.0 1 0 0 1 1 1 1 Adenylosuccinate synthetase Collagen PF01391.18 CBK20088.2 - 3.4e-05 23.5 5.7 3.4e-05 23.5 5.7 3.8 3 2 0 3 3 3 1 Collagen triple helix repeat (20 copies) Pkinase PF00069.25 CBK20089.2 - 1.2e-75 254.3 0.0 1.6e-75 253.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBK20089.2 - 4.4e-39 134.3 0.0 6.3e-39 133.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PX PF00787.24 CBK20089.2 - 3.9e-10 39.7 0.2 1.7e-09 37.7 0.0 2.1 2 0 0 2 2 2 1 PX domain Kinase-like PF14531.6 CBK20089.2 - 3.2e-06 26.7 0.0 4.5e-05 22.9 0.0 2.1 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 CBK20089.2 - 0.00053 18.9 0.0 0.001 17.9 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase FTA2 PF13095.6 CBK20089.2 - 0.00067 19.3 0.1 0.31 10.6 0.1 2.3 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Pkinase_C PF00433.24 CBK20089.2 - 0.015 16.0 1.7 0.04 14.6 1.7 1.8 1 0 0 1 1 1 0 Protein kinase C terminal domain APH PF01636.23 CBK20089.2 - 0.074 13.0 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family PrmA PF06325.13 CBK20091.2 - 1.8e-10 40.7 0.0 2.5e-10 40.2 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.6 CBK20091.2 - 1.1e-07 32.4 0.0 2.7e-07 31.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CBK20091.2 - 1.1e-05 25.3 0.0 1.9e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 CBK20091.2 - 0.00028 20.5 0.0 0.00044 19.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_11 PF08241.12 CBK20091.2 - 0.00034 21.2 0.0 0.00092 19.8 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Cons_hypoth95 PF03602.15 CBK20091.2 - 0.00044 19.9 0.0 0.00079 19.1 0.0 1.4 1 1 0 1 1 1 1 Conserved hypothetical protein 95 DOT1 PF08123.13 CBK20091.2 - 0.00079 19.0 0.0 0.0011 18.5 0.0 1.2 1 0 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_4 PF02390.17 CBK20091.2 - 0.0019 17.7 0.0 0.0031 17.0 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_23 PF13489.6 CBK20091.2 - 0.0043 16.9 0.0 0.0067 16.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.7 CBK20091.2 - 0.0063 16.5 0.0 0.018 15.0 0.0 1.7 1 1 1 2 2 2 1 Methyltransferase domain PCMT PF01135.19 CBK20091.2 - 0.0066 16.2 0.0 0.01 15.6 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_12 PF08242.12 CBK20091.2 - 0.0076 17.0 0.0 0.015 16.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 CBK20091.2 - 0.025 13.9 0.0 0.034 13.4 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_32 PF13679.6 CBK20091.2 - 0.026 14.5 0.0 0.047 13.7 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain tRNA_U5-meth_tr PF05958.11 CBK20091.2 - 0.026 13.5 0.0 0.035 13.1 0.0 1.1 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase PRMT5 PF05185.16 CBK20091.2 - 0.045 13.6 0.0 0.078 12.8 0.0 1.3 1 0 0 1 1 1 0 PRMT5 arginine-N-methyltransferase Homeobox_KN PF05920.11 CBK20092.2 - 5.3e-14 51.8 0.8 1.1e-13 50.8 0.8 1.6 1 0 0 1 1 1 1 Homeobox KN domain Homeodomain PF00046.29 CBK20092.2 - 2.6e-08 33.6 0.4 4.6e-08 32.8 0.3 1.5 1 1 0 1 1 1 1 Homeodomain Proteasome PF00227.26 CBK20093.2 - 1.3e-32 112.9 0.0 1.5e-32 112.6 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 CBK20093.2 - 2.9e-12 46.0 1.3 1.3e-10 40.7 0.0 2.6 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature Shufflon_N PF04917.12 CBK20093.2 - 0.015 14.8 0.0 0.02 14.3 0.0 1.2 1 0 0 1 1 1 0 Bacterial shufflon protein, N-terminal constant region Radical_SAM_C PF16199.5 CBK20094.2 - 6.9e-30 102.9 0.0 1.5e-29 101.8 0.0 1.6 1 0 0 1 1 1 1 Radical_SAM C-terminal domain Radical_SAM PF04055.21 CBK20094.2 - 1.3e-16 61.4 0.1 2.9e-15 57.0 0.1 2.5 3 0 0 3 3 3 1 Radical SAM superfamily Acetyltransf_1 PF00583.25 CBK20094.2 - 5.4e-12 46.0 0.1 1.1e-11 45.0 0.1 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 CBK20094.2 - 4.8e-05 23.3 0.1 0.00011 22.1 0.1 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 CBK20094.2 - 0.0023 18.3 0.0 0.0044 17.4 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 CBK20094.2 - 0.15 12.1 0.0 0.39 10.7 0.0 1.7 2 0 0 2 2 2 0 FR47-like protein CDC27 PF09507.10 CBK20095.2 - 0.6 9.4 26.9 1 8.7 26.9 1.3 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 CDK2AP PF09806.9 CBK20095.2 - 0.98 9.4 10.2 1.5 8.8 10.2 1.2 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein Neur_chan_memb PF02932.16 CBK20095.2 - 1.4 8.9 6.7 1.8 8.6 6.7 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Menin PF05053.13 CBK20095.2 - 3.6 5.8 8.5 4.1 5.6 8.5 1.2 1 0 0 1 1 1 0 Menin Ndc1_Nup PF09531.10 CBK20095.2 - 6.4 5.3 7.6 7.5 5.1 7.6 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Hid1 PF12722.7 CBK20095.2 - 7.4 4.6 14.5 8.5 4.4 14.5 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein WD40 PF00400.32 CBK20096.2 - 9.4e-24 83.3 21.0 1.5e-05 25.7 0.1 8.4 8 0 0 8 8 8 6 WD domain, G-beta repeat Ge1_WD40 PF16529.5 CBK20096.2 - 5.3e-06 25.6 1.6 0.94 8.4 0.0 4.2 3 2 1 4 4 4 3 WD40 region of Ge1, enhancer of mRNA-decapping protein ANAPC4_WD40 PF12894.7 CBK20096.2 - 7.2e-05 23.0 0.0 13 6.2 0.0 5.2 4 2 2 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain Nucleoporin_N PF08801.11 CBK20096.2 - 0.0035 16.1 0.2 0.032 13.0 0.1 2.4 2 1 0 2 2 2 1 Nup133 N terminal like PDZ_6 PF17820.1 CBK20096.2 - 0.029 14.2 0.0 0.061 13.2 0.0 1.5 1 0 0 1 1 1 0 PDZ domain PDZ_2 PF13180.6 CBK20096.2 - 0.16 12.3 0.0 0.33 11.3 0.0 1.5 1 0 0 1 1 1 0 PDZ domain WD40 PF00400.32 CBK20097.2 - 5.8e-17 61.8 2.7 5.2e-05 23.9 0.7 5.3 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBK20097.2 - 0.0015 18.8 0.9 1.8 8.9 0.2 3.8 1 1 3 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 CBK20097.2 - 0.0075 15.0 0.2 0.44 9.1 0.1 2.1 2 0 0 2 2 2 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 CBK20097.2 - 0.029 13.1 0.3 0.4 9.4 0.0 2.2 3 0 0 3 3 3 0 Nup133 N terminal like YecM PF06185.12 CBK20097.2 - 0.14 11.8 0.0 0.36 10.5 0.0 1.6 2 0 0 2 2 2 0 YecM protein RNase_T PF00929.24 CBK20098.2 - 4.1e-18 66.5 0.0 5.8e-18 66.0 0.0 1.2 1 0 0 1 1 1 1 Exonuclease Maf PF02545.14 CBK20098.2 - 4.8e-17 62.3 0.0 1e-16 61.3 0.0 1.5 1 0 0 1 1 1 1 Maf-like protein TFIIF_alpha PF05793.12 CBK20098.2 - 0.15 10.6 14.4 0.19 10.3 14.4 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Ribosomal_L31e PF01198.19 CBK20099.2 - 6.3e-31 106.4 0.3 8e-31 106.1 0.3 1.1 1 0 0 1 1 1 1 Ribosomal protein L31e VPS9 PF02204.18 CBK20100.2 - 1.9e-28 98.7 0.0 3e-28 98.1 0.0 1.2 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain OmpH PF03938.14 CBK20100.2 - 0.03 14.7 1.1 0.048 14.0 1.1 1.4 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) SseC PF04888.12 CBK20100.2 - 0.047 13.3 0.6 0.062 12.9 0.6 1.1 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family DUF5601 PF18151.1 CBK20100.2 - 0.093 13.1 0.0 0.25 11.7 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF5601) DEAD PF00270.29 CBK20101.2 - 1.2e-43 148.9 0.0 1.9e-43 148.2 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CBK20101.2 - 2.9e-26 92.0 0.0 6.5e-26 90.9 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain GUCT PF08152.12 CBK20101.2 - 2.5e-21 75.8 0.0 8.2e-21 74.1 0.0 1.9 1 0 0 1 1 1 1 GUCT (NUC152) domain ERCC3_RAD25_C PF16203.5 CBK20101.2 - 0.052 12.8 0.0 0.082 12.1 0.0 1.2 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase CMS1 PF14617.6 CBK20101.2 - 0.1 11.9 0.0 0.21 10.9 0.0 1.4 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit ResIII PF04851.15 CBK20101.2 - 0.19 11.8 0.0 0.42 10.6 0.0 1.6 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit RRM_1 PF00076.22 CBK20102.2 - 1.8e-57 191.1 6.4 1e-13 50.9 0.0 4.3 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.18 CBK20102.2 - 2.6e-17 62.7 0.0 8.4e-17 61.1 0.0 1.9 1 0 0 1 1 1 1 Poly-adenylate binding protein, unique domain RRM_3 PF08777.11 CBK20102.2 - 6.3e-08 32.6 7.2 0.00055 19.9 0.1 4.2 4 0 0 4 4 4 3 RNA binding motif Clathrin_lg_ch PF01086.17 CBK20102.2 - 0.038 14.0 0.4 0.038 14.0 0.4 2.0 2 0 0 2 2 2 0 Clathrin light chain Nup35_RRM_2 PF14605.6 CBK20102.2 - 0.1 12.6 4.3 7.6 6.6 0.0 4.0 5 0 0 5 5 5 0 Nup53/35/40-type RNA recognition motif NUSAP PF16006.5 CBK20102.2 - 5.6 6.6 9.9 0.041 13.6 1.2 1.8 2 0 0 2 2 2 0 Nucleolar and spindle-associated protein LRR_4 PF12799.7 CBK20104.2 - 0.00086 19.7 1.3 3 8.4 0.2 4.3 1 1 3 4 4 4 2 Leucine Rich repeats (2 copies) RNA_pol_Rpb4 PF03874.16 CBK20106.2 - 1e-08 35.5 0.0 1.6e-08 34.9 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb4 Na_Ca_ex PF01699.24 CBK20107.2 - 2.4e-17 63.3 16.6 2.4e-17 63.3 16.6 2.2 2 0 0 2 2 2 1 Sodium/calcium exchanger protein YfhO PF09586.10 CBK20107.2 - 0.3 9.3 6.6 0.064 11.5 0.4 2.2 2 1 1 3 3 3 0 Bacterial membrane protein YfhO SMC_N PF02463.19 CBK20108.2 - 2.1e-18 66.6 12.1 3.4e-18 65.9 12.1 1.4 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 CBK20108.2 - 6.8e-06 26.1 2.5 1.1e-05 25.4 2.5 1.3 1 1 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system CENP-K PF11802.8 CBK20108.2 - 0.0068 16.0 2.9 0.0068 16.0 2.9 2.3 2 0 0 2 2 2 1 Centromere-associated protein K SbcCD_C PF13558.6 CBK20108.2 - 0.0089 16.2 0.0 0.024 14.9 0.0 1.7 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit Cas_APE2256 PF09651.10 CBK20108.2 - 0.014 15.3 0.0 0.052 13.5 0.0 2.1 1 1 0 1 1 1 0 CRISPR-associated protein (Cas_APE2256) ATR13 PF16829.5 CBK20108.2 - 0.017 15.4 0.1 0.05 13.9 0.1 1.8 2 0 0 2 2 2 0 Avirulence protein ATR13, RxLR effector DUF4407 PF14362.6 CBK20108.2 - 0.09 12.1 18.2 2.4 7.4 15.4 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Snapin_Pallidin PF14712.6 CBK20108.2 - 0.24 11.8 19.5 1.7 9.2 5.9 3.5 3 0 0 3 3 3 0 Snapin/Pallidin ABC_tran PF00005.27 CBK20108.2 - 0.78 10.3 9.9 27 5.3 9.9 2.7 1 1 0 1 1 1 0 ABC transporter CCDC92 PF14916.6 CBK20108.2 - 0.83 9.5 12.8 1.6 8.5 3.2 2.6 2 0 0 2 2 2 0 Coiled-coil domain of unknown function Exonuc_VII_L PF02601.15 CBK20108.2 - 1.1 8.8 12.3 1.5 8.3 12.3 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit Seryl_tRNA_N PF02403.22 CBK20108.2 - 1.9 8.8 25.5 5.9 7.2 11.1 2.6 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Allexi_40kDa PF05549.11 CBK20108.2 - 2.1 7.8 13.1 2.5 7.5 2.7 2.2 2 0 0 2 2 2 0 Allexivirus 40kDa protein GPHR_N PF12537.8 CBK20108.2 - 6.4 6.9 5.7 15 5.8 1.6 3.3 3 1 0 3 3 3 0 The Golgi pH Regulator (GPHR) Family N-terminal SMC_N PF02463.19 CBK20109.2 - 1.3e-19 70.6 0.1 1.3e-19 70.6 0.1 1.9 2 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 CBK20109.2 - 1.6e-15 58.2 27.5 5.1e-14 53.3 27.5 2.3 1 1 0 1 1 1 1 AAA domain AAA_15 PF13175.6 CBK20109.2 - 5.3e-09 36.3 8.7 7.9e-09 35.7 8.7 1.2 1 0 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 CBK20109.2 - 4.2e-08 32.8 0.0 1.1e-07 31.5 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_21 PF13304.6 CBK20109.2 - 1.4e-05 25.1 0.1 3.5e-05 23.8 0.1 1.9 1 1 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system MMR_HSR1 PF01926.23 CBK20109.2 - 0.0031 17.6 0.1 0.018 15.1 0.0 2.1 2 0 0 2 2 2 1 50S ribosome-binding GTPase ABC_tran PF00005.27 CBK20109.2 - 0.0061 17.1 4.5 0.014 15.9 0.0 2.8 2 1 0 2 2 2 1 ABC transporter CENP-K PF11802.8 CBK20109.2 - 0.0081 15.8 15.2 0.013 15.0 15.2 1.3 1 0 0 1 1 1 1 Centromere-associated protein K MukB PF04310.12 CBK20109.2 - 0.07 12.9 0.1 0.59 9.9 0.0 2.3 3 0 0 3 3 3 0 MukB N-terminal RsgA_GTPase PF03193.16 CBK20109.2 - 0.1 12.5 0.3 0.33 10.8 0.0 2.0 2 1 0 2 2 2 0 RsgA GTPase AAA_27 PF13514.6 CBK20109.2 - 0.23 11.0 5.4 0.35 10.4 0.0 2.8 2 1 1 3 3 3 0 AAA domain DUF745 PF05335.13 CBK20109.2 - 0.26 11.0 5.3 0.49 10.1 5.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF745) FUSC-like PF12805.7 CBK20109.2 - 0.47 9.5 10.7 0.1 11.6 7.2 1.4 1 1 0 1 1 1 0 FUSC-like inner membrane protein yccS PI_PP_I PF18363.1 CBK20109.2 - 0.54 10.5 5.0 0.61 10.3 0.3 2.8 1 1 1 2 2 2 0 Phosphoinositide phosphatase insertion domain MALT1_Ig PF18703.1 CBK20109.2 - 1.1 9.3 5.6 0.3 11.1 0.2 2.7 2 1 1 3 3 3 0 MALT1 Ig-like domain DUF4407 PF14362.6 CBK20109.2 - 1.7 8.0 5.1 2.5 7.4 5.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Fer2_3 PF13085.6 CBK20110.2 - 2.2e-33 114.5 0.1 3.8e-33 113.7 0.1 1.4 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer4_17 PF13534.6 CBK20110.2 - 1.7e-08 34.9 6.5 1.7e-08 34.9 6.5 2.1 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_8 PF13183.6 CBK20110.2 - 2e-08 34.5 7.7 2e-08 34.5 7.7 2.4 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_10 PF13237.6 CBK20110.2 - 2.3e-07 30.8 3.4 2.3e-07 30.8 3.4 2.2 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer2 PF00111.27 CBK20110.2 - 0.00035 20.5 0.4 0.00035 20.5 0.4 2.1 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fer4_7 PF12838.7 CBK20110.2 - 0.0033 18.0 5.1 0.0033 18.0 5.1 2.8 2 2 0 2 2 2 1 4Fe-4S dicluster domain Fer4_9 PF13187.6 CBK20110.2 - 0.029 14.5 8.2 0.029 14.5 8.2 2.6 2 1 0 2 2 2 0 4Fe-4S dicluster domain Herpes_UL51 PF04540.13 CBK20110.2 - 0.11 12.2 0.0 0.18 11.5 0.0 1.3 1 0 0 1 1 1 0 Herpesvirus UL51 protein Sec6 PF06046.13 CBK20111.2 - 2.9e-06 25.9 0.3 7.8e-06 24.5 0.0 1.7 2 0 0 2 2 2 1 Exocyst complex component Sec6 Phage_GP20 PF06810.11 CBK20111.2 - 0.0064 16.3 3.0 0.011 15.6 3.0 1.3 1 0 0 1 1 1 1 Phage minor structural protein GP20 Aldo_ket_red PF00248.21 CBK20111.2 - 0.011 15.0 0.2 0.022 14.0 0.1 1.4 1 1 0 1 1 1 0 Aldo/keto reductase family Zw10 PF06248.13 CBK20111.2 - 0.018 13.6 4.0 0.023 13.3 4.0 1.1 1 0 0 1 1 1 0 Centromere/kinetochore Zw10 DUF16 PF01519.16 CBK20111.2 - 0.024 15.1 3.3 0.024 15.1 3.3 2.1 1 1 1 2 2 2 0 Protein of unknown function DUF16 DUF724 PF05266.14 CBK20111.2 - 0.027 14.3 0.5 0.046 13.6 0.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF724) Sigma70_ner PF04546.13 CBK20111.2 - 0.068 13.0 1.7 0.19 11.6 1.8 1.8 1 1 0 1 1 1 0 Sigma-70, non-essential region PRKG1_interact PF15898.5 CBK20111.2 - 0.096 13.6 3.7 0.27 12.2 3.7 1.8 1 0 0 1 1 1 0 cGMP-dependent protein kinase interacting domain NPV_P10 PF05531.12 CBK20111.2 - 0.16 12.5 6.6 3 8.4 3.2 3.0 1 1 3 4 4 4 0 Nucleopolyhedrovirus P10 protein HrpJ PF07201.11 CBK20111.2 - 0.17 12.2 3.0 1.2 9.4 0.1 2.4 2 0 0 2 2 2 0 HrpJ-like domain COG2 PF06148.11 CBK20111.2 - 0.23 11.6 4.1 0.7 10.0 3.5 2.1 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 ABC_tran_CTD PF16326.5 CBK20111.2 - 0.4 11.0 2.3 0.73 10.1 0.3 2.4 3 0 0 3 3 3 0 ABC transporter C-terminal domain Baculo_PEP_C PF04513.12 CBK20111.2 - 0.53 10.3 6.9 1.2 9.2 6.6 1.7 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF4094 PF13334.6 CBK20111.2 - 0.64 10.5 4.0 0.5 10.8 0.6 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4094) Mod_r PF07200.13 CBK20111.2 - 1.1 9.4 7.3 9.6 6.3 5.9 2.2 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein DUF5344 PF17279.2 CBK20111.2 - 1.3 9.7 6.6 3 8.5 0.9 3.2 2 1 2 4 4 4 0 Family of unknown function (DUF5344) E2F_CC-MB PF16421.5 CBK20111.2 - 1.4 9.3 9.1 2.9 8.3 0.2 3.7 2 1 2 4 4 3 0 E2F transcription factor CC-MB domain Syntaxin-6_N PF09177.11 CBK20111.2 - 8.7 7.0 7.6 17 6.1 3.4 3.0 2 2 0 2 2 2 0 Syntaxin 6, N-terminal Ribosomal_S3Ae PF01015.18 CBK20112.2 - 1.9e-84 282.3 2.9 2.5e-84 281.9 2.9 1.1 1 0 0 1 1 1 1 Ribosomal S3Ae family SUI1 PF01253.22 CBK20112.2 - 0.0012 19.3 0.4 0.0059 17.1 0.2 2.2 1 1 1 2 2 2 1 Translation initiation factor SUI1 Abhydro_lipase PF04083.16 CBK20112.2 - 0.021 14.4 0.1 0.067 12.8 0.0 1.9 2 0 0 2 2 2 0 Partial alpha/beta-hydrolase lipase region DUF3395 PF11875.8 CBK20112.2 - 0.068 13.1 0.1 0.26 11.2 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3395) DUF4407 PF14362.6 CBK20113.2 - 0.29 10.5 4.4 0.41 10.0 4.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) EMC3_TMCO1 PF01956.16 CBK20113.2 - 0.65 9.7 6.2 1.2 8.8 6.2 1.6 1 1 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like HAUS6_N PF14661.6 CBK20113.2 - 0.87 9.1 9.8 0.12 11.9 4.4 1.9 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus OEP PF02321.18 CBK20113.2 - 1.8 8.3 9.9 3.8 7.3 9.9 1.4 1 0 0 1 1 1 0 Outer membrane efflux protein DUF1216 PF06746.11 CBK20113.2 - 2.6 8.1 6.5 2.3 8.2 1.0 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1216) DUF4140 PF13600.6 CBK20113.2 - 3.5 8.1 6.9 7.2 7.1 4.4 2.5 2 1 1 3 3 3 0 N-terminal domain of unknown function (DUF4140) Synaptobrevin PF00957.21 CBK20114.2 - 0.00057 19.6 2.2 0.00065 19.5 1.7 1.3 1 1 0 1 1 1 1 Synaptobrevin SNARE PF05739.19 CBK20114.2 - 0.00064 19.7 1.8 0.0028 17.6 0.4 2.1 2 0 0 2 2 2 1 SNARE domain T2SSF PF00482.23 CBK20114.2 - 0.0057 16.6 0.1 0.0069 16.3 0.1 1.1 1 0 0 1 1 1 1 Type II secretion system (T2SS), protein F Cauli_AT PF03233.13 CBK20114.2 - 0.0088 16.0 1.6 0.01 15.8 1.6 1.1 1 0 0 1 1 1 1 Aphid transmission protein DUF2959 PF11172.8 CBK20114.2 - 0.012 15.8 1.0 0.014 15.5 1.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2959) HXXSHH PF07586.11 CBK20114.2 - 0.018 14.6 1.8 0.02 14.5 1.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1552) DUF3375 PF11855.8 CBK20114.2 - 0.022 13.7 4.5 0.025 13.5 4.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3375) Orf78 PF06024.12 CBK20114.2 - 0.034 14.4 1.3 0.039 14.2 0.9 1.4 1 1 0 1 1 1 0 Orf78 (ac78) DUF4519 PF15012.6 CBK20114.2 - 0.036 14.2 0.2 0.036 14.2 0.2 1.7 2 0 0 2 2 1 0 Domain of unknown function (DUF4519) DUF4404 PF14357.6 CBK20114.2 - 0.041 14.5 3.8 0.058 14.0 3.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4404) HGD-D PF06050.13 CBK20114.2 - 0.042 13.6 0.2 0.049 13.4 0.2 1.1 1 0 0 1 1 1 0 2-hydroxyglutaryl-CoA dehydratase, D-component DUF4407 PF14362.6 CBK20114.2 - 0.054 12.8 2.0 0.072 12.4 2.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) CASP_C PF08172.12 CBK20114.2 - 0.062 12.6 3.9 0.077 12.3 3.9 1.1 1 0 0 1 1 1 0 CASP C terminal HIP1_clath_bdg PF16515.5 CBK20114.2 - 0.08 13.6 10.1 0.16 12.6 10.1 1.5 1 1 0 1 1 1 0 Clathrin-binding domain of Huntingtin-interacting protein 1 MCU PF04678.13 CBK20114.2 - 0.083 13.0 1.6 0.091 12.8 1.6 1.1 1 0 0 1 1 1 0 Mitochondrial calcium uniporter Spc29 PF17082.5 CBK20114.2 - 0.11 12.4 3.6 0.13 12.1 3.6 1.1 1 0 0 1 1 1 0 Spindle Pole Component 29 DUF812 PF05667.11 CBK20114.2 - 0.12 11.2 11.1 0.14 11.0 11.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF812) Peptidase_C65 PF10275.9 CBK20114.2 - 0.14 11.5 1.6 0.16 11.4 1.6 1.0 1 0 0 1 1 1 0 Peptidase C65 Otubain Mis14 PF08641.12 CBK20114.2 - 0.26 11.6 5.1 0.34 11.2 5.1 1.2 1 0 0 1 1 1 0 Kinetochore protein Mis14 like PEP-utilisers_N PF05524.13 CBK20114.2 - 0.27 11.4 3.3 2.8 8.2 3.3 2.0 1 1 0 1 1 1 0 PEP-utilising enzyme, N-terminal DUF1664 PF07889.12 CBK20114.2 - 0.28 11.2 3.8 0.23 11.5 2.2 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) DUF3435 PF11917.8 CBK20114.2 - 0.31 9.9 3.7 0.34 9.8 3.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3435) RmuC PF02646.16 CBK20114.2 - 0.39 9.8 6.3 0.51 9.4 6.3 1.2 1 0 0 1 1 1 0 RmuC family PCRF PF03462.18 CBK20114.2 - 0.44 10.4 6.2 0.5 10.2 6.2 1.0 1 0 0 1 1 1 0 PCRF domain XhlA PF10779.9 CBK20114.2 - 0.68 10.2 10.7 2.8 8.2 2.8 2.2 1 1 1 2 2 2 0 Haemolysin XhlA DUF16 PF01519.16 CBK20114.2 - 0.72 10.4 8.8 10 6.7 8.8 2.0 1 1 0 1 1 1 0 Protein of unknown function DUF16 DUF4298 PF14131.6 CBK20114.2 - 0.79 9.7 4.7 4.5 7.3 0.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4298) HSCB_C PF07743.13 CBK20114.2 - 1.2 9.7 7.5 0.79 10.3 2.2 1.9 1 1 1 2 2 2 0 HSCB C-terminal oligomerisation domain DUF745 PF05335.13 CBK20114.2 - 1.2 8.8 5.7 1.4 8.6 5.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF745) FapA PF03961.13 CBK20114.2 - 1.4 7.5 6.2 1.5 7.3 6.2 1.0 1 0 0 1 1 1 0 Flagellar Assembly Protein A DASH_Dad4 PF08650.10 CBK20114.2 - 1.9 8.5 5.7 2.5 8.1 2.0 2.1 2 0 0 2 2 2 0 DASH complex subunit Dad4 Phage_holin_6_1 PF09682.10 CBK20114.2 - 2.1 8.8 8.4 1.1 9.7 0.8 2.1 2 0 0 2 2 2 0 Bacteriophage holin of superfamily 6 (Holin_LLH) Nup54 PF13874.6 CBK20114.2 - 2.6 8.1 8.8 8.6 6.5 8.8 1.7 1 1 0 1 1 1 0 Nucleoporin complex subunit 54 DUF948 PF06103.11 CBK20114.2 - 3.4 8.0 12.3 2.6 8.4 0.1 2.7 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) SlyX PF04102.12 CBK20114.2 - 4 8.1 10.2 2.3 8.9 2.2 2.3 1 1 1 2 2 2 0 SlyX UPF0242 PF06785.11 CBK20114.2 - 5.2 7.1 9.7 6.5 6.8 9.7 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus EMP24_GP25L PF01105.24 CBK20114.2 - 5.6 6.9 8.2 48 3.8 8.2 2.0 1 1 0 1 1 1 0 emp24/gp25L/p24 family/GOLD TB2_DP1_HVA22 PF03134.19 CBK20115.2 - 1e-05 25.4 1.5 1e-05 25.4 1.5 2.5 1 1 1 2 2 2 1 TB2/DP1, HVA22 family PigN PF04987.14 CBK20115.2 - 0.00023 20.1 1.5 0.00026 20.0 1.5 1.0 1 0 0 1 1 1 1 Phosphatidylinositolglycan class N (PIG-N) PNP_UDP_1 PF01048.20 CBK20117.2 - 2.1e-32 112.3 0.1 2.5e-32 112.0 0.1 1.0 1 0 0 1 1 1 1 Phosphorylase superfamily W2 PF02020.18 CBK20118.2 - 0.0038 17.3 0.3 0.0038 17.3 0.3 2.7 2 0 0 2 2 2 1 eIF4-gamma/eIF5/eIF2-epsilon Abhydrolase_9_N PF15420.6 CBK20118.2 - 0.24 11.4 0.9 0.48 10.4 0.9 1.4 1 0 0 1 1 1 0 Alpha/beta-hydrolase family N-terminus UAA PF08449.11 CBK20119.2 - 1.3e-32 113.2 11.6 1.5e-32 113.0 11.6 1.0 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.20 CBK20119.2 - 0.00015 21.9 6.5 0.00015 21.9 6.5 2.1 2 0 0 2 2 2 1 EamA-like transporter family CRT-like PF08627.10 CBK20119.2 - 0.00051 19.1 3.3 0.00051 19.1 3.3 1.9 1 1 1 2 2 2 1 CRT-like, chloroquine-resistance transporter-like Nuc_sug_transp PF04142.15 CBK20119.2 - 0.037 13.2 4.4 0.057 12.6 4.4 1.4 1 1 0 1 1 1 0 Nucleotide-sugar transporter ASFV_J13L PF05568.11 CBK20119.2 - 0.25 11.1 0.4 0.54 10.0 0.4 1.5 1 0 0 1 1 1 0 African swine fever virus J13L protein bZIP_1 PF00170.21 CBK20120.2 - 2.9e-07 30.5 11.7 6.1e-07 29.4 11.7 1.5 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 CBK20120.2 - 0.00011 22.2 13.5 0.00014 21.8 12.9 1.6 1 1 0 1 1 1 1 Basic region leucine zipper OrfB_IS605 PF01385.19 CBK20120.2 - 0.11 12.7 1.5 0.2 11.9 1.5 1.4 1 0 0 1 1 1 0 Probable transposase Acetyltransf_1 PF00583.25 CBK20121.2 - 2e-11 44.2 0.0 2.5e-11 43.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 CBK20121.2 - 1.6e-09 38.0 0.0 2.3e-09 37.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 CBK20121.2 - 1.8e-09 37.6 0.0 1.9e-09 37.6 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 CBK20121.2 - 1.7e-08 34.3 0.0 2.1e-08 34.0 0.0 1.1 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 CBK20121.2 - 9.9e-05 22.4 0.0 0.00013 22.0 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_15 PF17013.5 CBK20121.2 - 0.00094 18.7 0.3 0.011 15.2 0.3 2.0 1 1 0 1 1 1 1 Putative acetyl-transferase Acetyltransf_3 PF13302.7 CBK20121.2 - 0.0087 16.7 0.0 0.011 16.4 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain GNAT_acetyltran PF12746.7 CBK20121.2 - 0.034 13.7 0.0 0.043 13.4 0.0 1.1 1 0 0 1 1 1 0 GNAT acetyltransferase Acetyltransf_8 PF13523.6 CBK20121.2 - 0.056 13.1 0.0 0.083 12.6 0.0 1.3 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Gly_acyl_tr_C PF08444.10 CBK20121.2 - 0.12 12.6 0.0 0.26 11.5 0.0 1.5 1 1 1 2 2 2 0 Aralkyl acyl-CoA:amino acid N-acyltransferase, C-terminal region V-ATPase_H_C PF11698.8 CBK20122.2 - 4e-36 123.7 4.6 2.7e-33 114.5 0.0 3.2 3 0 0 3 3 3 2 V-ATPase subunit H V-ATPase_H_N PF03224.14 CBK20122.2 - 6.4e-21 74.9 10.0 7.2e-20 71.5 2.3 2.4 2 0 0 2 2 2 2 V-ATPase subunit H LINES_N PF14694.6 CBK20122.2 - 0.018 14.5 2.6 0.062 12.8 0.2 2.3 2 0 0 2 2 2 0 Lines N-terminus AAA PF00004.29 CBK20123.2 - 1.1e-36 126.2 0.0 2.2e-36 125.2 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CBK20123.2 - 6.6e-08 32.2 0.0 1.4e-07 31.1 0.0 1.5 1 0 0 1 1 1 1 AAA+ lid domain AAA_33 PF13671.6 CBK20123.2 - 1.2e-05 25.5 0.0 5.6e-05 23.3 0.0 2.1 2 1 1 3 3 2 1 AAA domain AAA_22 PF13401.6 CBK20123.2 - 2.1e-05 24.8 0.2 0.0021 18.3 0.1 3.0 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.6 CBK20123.2 - 2.1e-05 25.0 0.0 0.0019 18.6 0.0 2.4 1 1 1 2 2 2 1 AAA ATPase domain RuvB_N PF05496.12 CBK20123.2 - 4e-05 23.4 0.0 0.0001 22.1 0.0 1.7 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 CBK20123.2 - 4.9e-05 23.3 0.2 0.00049 20.1 0.2 2.6 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) TIP49 PF06068.13 CBK20123.2 - 7e-05 22.2 0.1 0.00023 20.5 0.0 1.7 1 1 1 2 2 2 1 TIP49 P-loop domain AAA_18 PF13238.6 CBK20123.2 - 0.00015 22.3 0.0 0.00064 20.3 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_2 PF07724.14 CBK20123.2 - 0.00023 21.3 0.0 0.00094 19.3 0.0 1.9 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_14 PF13173.6 CBK20123.2 - 0.00023 21.2 0.1 0.0028 17.7 0.0 2.2 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.21 CBK20123.2 - 0.0011 18.4 0.1 0.0022 17.4 0.1 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_6 PF12774.7 CBK20123.2 - 0.0014 17.7 0.1 0.092 11.7 0.0 2.7 2 1 1 3 3 3 1 Hydrolytic ATP binding site of dynein motor region AAA_24 PF13479.6 CBK20123.2 - 0.0014 18.3 0.1 0.0056 16.4 0.0 2.0 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 CBK20123.2 - 0.0016 18.2 0.0 0.003 17.3 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein RNA_helicase PF00910.22 CBK20123.2 - 0.0018 18.6 0.5 0.023 15.1 0.0 2.8 3 0 0 3 3 3 1 RNA helicase AAA_28 PF13521.6 CBK20123.2 - 0.0029 17.9 0.0 0.0061 16.8 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_7 PF12775.7 CBK20123.2 - 0.0036 16.8 0.1 0.011 15.2 0.1 1.9 2 1 0 2 2 1 1 P-loop containing dynein motor region DUF815 PF05673.13 CBK20123.2 - 0.004 16.3 0.0 0.019 14.1 0.0 2.1 1 1 1 2 2 2 1 Protein of unknown function (DUF815) TsaE PF02367.17 CBK20123.2 - 0.0046 16.9 0.0 0.0095 15.9 0.0 1.5 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE TniB PF05621.11 CBK20123.2 - 0.0057 16.1 0.0 2.7 7.4 0.0 2.4 1 1 0 2 2 2 1 Bacterial TniB protein IPT PF01745.16 CBK20123.2 - 0.0073 15.7 0.0 0.013 14.9 0.0 1.4 1 0 0 1 1 1 1 Isopentenyl transferase NACHT PF05729.12 CBK20123.2 - 0.0092 15.9 0.4 0.041 13.8 0.1 2.4 3 1 0 3 3 3 1 NACHT domain Sigma54_activ_2 PF14532.6 CBK20123.2 - 0.01 15.9 0.0 0.031 14.4 0.0 1.8 1 0 0 1 1 1 0 Sigma-54 interaction domain Parvo_NS1 PF01057.17 CBK20123.2 - 0.011 14.8 0.0 0.021 13.9 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_17 PF13207.6 CBK20123.2 - 0.014 15.8 0.1 0.055 13.9 0.0 2.1 2 0 0 2 2 1 0 AAA domain CPT PF07931.12 CBK20123.2 - 0.019 14.8 0.0 0.035 13.9 0.0 1.4 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein AAA_25 PF13481.6 CBK20123.2 - 0.02 14.4 0.0 0.056 13.0 0.0 1.7 2 0 0 2 2 2 0 AAA domain Sigma54_activat PF00158.26 CBK20123.2 - 0.022 14.5 0.0 0.051 13.3 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_3 PF07726.11 CBK20123.2 - 0.025 14.4 0.0 0.054 13.4 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 CBK20123.2 - 0.026 14.4 0.3 0.12 12.2 0.0 2.1 2 1 1 3 3 3 0 Rad17 P-loop domain Zeta_toxin PF06414.12 CBK20123.2 - 0.046 13.0 0.1 0.27 10.5 0.0 2.2 3 0 0 3 3 3 0 Zeta toxin SKI PF01202.22 CBK20123.2 - 0.076 13.1 0.0 0.36 11.0 0.0 2.1 2 0 0 2 2 2 0 Shikimate kinase PhoH PF02562.16 CBK20123.2 - 0.11 12.0 0.0 0.23 10.9 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein FKBP_C PF00254.28 CBK20124.2 - 1e-33 115.5 0.0 1.1e-32 112.3 0.0 2.2 2 0 0 2 2 2 1 FKBP-type peptidyl-prolyl cis-trans isomerase Shisa PF13908.6 CBK20124.2 - 0.34 11.1 1.4 0.63 10.3 1.4 1.4 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator Enolase_C PF00113.22 CBK20125.2 - 2.7e-118 394.5 0.0 3.8e-118 394.0 0.0 1.1 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.16 CBK20125.2 - 5.1e-54 182.0 0.0 9.2e-54 181.1 0.0 1.5 1 0 0 1 1 1 1 Enolase, N-terminal domain MR_MLE_C PF13378.6 CBK20125.2 - 1.7e-06 27.8 0.0 3e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 Enolase C-terminal domain-like MAAL_C PF07476.11 CBK20125.2 - 0.00037 19.7 0.0 0.00059 19.1 0.0 1.2 1 0 0 1 1 1 1 Methylaspartate ammonia-lyase C-terminus Prokineticin PF06607.11 CBK20125.2 - 0.08 13.3 0.5 7.1 7.0 0.0 2.5 2 0 0 2 2 2 0 Prokineticin Pre-PUA PF17832.1 CBK20126.2 - 5.6e-11 43.0 0.9 1.8e-10 41.4 0.1 2.3 2 0 0 2 2 2 1 Pre-PUA-like domain SUI1 PF01253.22 CBK20126.2 - 3.8e-08 33.7 1.5 4.3e-08 33.6 0.3 1.7 2 0 0 2 2 2 1 Translation initiation factor SUI1 DUF1947 PF09183.10 CBK20126.2 - 0.17 12.2 1.3 0.56 10.5 0.2 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF1947) IPK PF03770.16 CBK20128.2 - 1.1e-07 31.9 0.0 2.1e-07 31.0 0.0 1.5 1 1 0 1 1 1 1 Inositol polyphosphate kinase DnaJ_CXXCXGXG PF00684.19 CBK20129.2 - 2.4e-05 24.6 23.1 0.0002 21.6 22.7 2.7 1 1 1 2 2 2 2 DnaJ central domain DUF5351 PF17302.2 CBK20129.2 - 0.066 13.4 30.2 1.4 9.2 2.9 4.6 4 0 0 4 4 4 0 Family of unknown function (DUF5351) Anti-TRAP PF15777.5 CBK20129.2 - 1 9.4 21.1 93 3.1 13.8 3.8 1 1 1 2 2 2 0 Tryptophan RNA-binding attenuator protein inhibitory protein DUF3439 PF11921.8 CBK20129.2 - 2.4 8.1 8.8 7.2 6.6 8.8 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF3439) DUF1356 PF07092.12 CBK20129.2 - 5.8 6.1 12.7 1.9 7.7 2.5 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1356) Peptidase_M99_C PF17129.4 CBK20130.2 - 0.068 13.4 0.1 0.3 11.3 0.1 2.1 1 0 0 1 1 1 0 C-terminal domain of metallo-carboxypeptidase ABC_tran PF00005.27 CBK20132.2 - 2.3e-73 245.2 0.0 1.5e-37 129.1 0.0 2.7 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 CBK20132.2 - 2.2e-57 194.8 14.7 2.4e-29 102.9 1.1 2.3 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.19 CBK20132.2 - 9.4e-12 44.8 1.0 0.00054 19.5 0.1 4.3 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 CBK20132.2 - 2.8e-11 44.1 0.0 0.00034 21.1 0.0 3.1 2 1 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 CBK20132.2 - 9.4e-11 42.1 1.7 0.00094 19.5 0.2 4.2 2 2 1 3 3 3 2 AAA domain AAA PF00004.29 CBK20132.2 - 1.3e-08 35.3 0.1 0.0012 19.3 0.0 4.2 2 2 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.6 CBK20132.2 - 1.5e-08 34.2 0.3 0.0038 16.9 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 CBK20132.2 - 1.8e-08 34.5 0.0 0.0095 15.8 0.0 2.6 2 0 0 2 2 2 2 RsgA GTPase AAA_21 PF13304.6 CBK20132.2 - 3.6e-08 33.6 0.7 0.84 9.4 0.2 4.3 3 1 1 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system G-alpha PF00503.20 CBK20132.2 - 1e-06 28.2 0.3 0.045 12.9 0.0 2.9 3 0 0 3 3 3 2 G-protein alpha subunit ABC_ATPase PF09818.9 CBK20132.2 - 2.2e-06 26.7 0.7 0.025 13.4 0.0 3.0 3 0 0 3 3 3 2 Predicted ATPase of the ABC class AAA_25 PF13481.6 CBK20132.2 - 4.1e-06 26.5 0.5 0.43 10.1 0.0 3.8 4 0 0 4 4 4 2 AAA domain AAA_30 PF13604.6 CBK20132.2 - 7.3e-06 25.8 1.0 0.28 10.9 0.2 3.8 2 2 1 3 3 2 2 AAA domain AAA_5 PF07728.14 CBK20132.2 - 1.7e-05 24.8 0.5 1.8 8.6 0.0 4.3 4 0 0 4 4 4 1 AAA domain (dynein-related subfamily) SbcCD_C PF13558.6 CBK20132.2 - 2.2e-05 24.6 4.2 0.066 13.5 0.8 3.8 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_18 PF13238.6 CBK20132.2 - 2.6e-05 24.8 0.4 0.73 10.4 0.0 4.0 4 0 0 4 4 4 2 AAA domain AAA_23 PF13476.6 CBK20132.2 - 6.2e-05 23.6 8.0 0.031 14.8 0.0 3.2 3 0 0 3 3 3 2 AAA domain IstB_IS21 PF01695.17 CBK20132.2 - 9.3e-05 22.2 0.1 1.5 8.5 0.0 3.8 4 0 0 4 4 3 1 IstB-like ATP binding protein Rad17 PF03215.15 CBK20132.2 - 9.4e-05 22.4 0.0 0.063 13.2 0.0 2.6 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_7 PF12775.7 CBK20132.2 - 0.00014 21.4 1.6 0.083 12.4 0.0 2.7 3 0 0 3 3 2 2 P-loop containing dynein motor region MMR_HSR1 PF01926.23 CBK20132.2 - 0.00024 21.2 0.1 0.59 10.2 0.0 3.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase RNA_helicase PF00910.22 CBK20132.2 - 0.00043 20.6 0.0 1.5 9.3 0.0 3.3 3 0 0 3 3 2 1 RNA helicase PRK PF00485.18 CBK20132.2 - 0.00062 19.6 0.3 0.51 10.1 0.1 2.7 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family NB-ARC PF00931.22 CBK20132.2 - 0.00095 18.4 0.1 1.1 8.4 0.0 2.7 2 0 0 2 2 2 2 NB-ARC domain DEAD PF00270.29 CBK20132.2 - 0.0013 18.5 0.5 0.57 9.9 0.1 3.6 2 2 0 2 2 2 1 DEAD/DEAH box helicase AAA_24 PF13479.6 CBK20132.2 - 0.0014 18.4 0.3 1 9.1 0.1 3.2 2 2 0 2 2 2 1 AAA domain Sigma54_activat PF00158.26 CBK20132.2 - 0.0022 17.7 0.0 4.6 6.9 0.0 3.4 3 0 0 3 3 3 0 Sigma-54 interaction domain AAA_33 PF13671.6 CBK20132.2 - 0.0023 18.1 0.5 2.2 8.4 0.1 2.9 2 1 0 2 2 2 1 AAA domain PhoH PF02562.16 CBK20132.2 - 0.0037 16.7 0.4 4.9 6.5 0.0 3.6 4 0 0 4 4 3 0 PhoH-like protein MeaB PF03308.16 CBK20132.2 - 0.0046 16.0 0.1 0.71 8.8 0.0 2.4 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB ATP_bind_1 PF03029.17 CBK20132.2 - 0.0053 16.6 0.5 0.39 10.5 0.0 2.7 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein Roc PF08477.13 CBK20132.2 - 0.0075 16.5 0.0 4 7.7 0.0 3.5 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase DUF87 PF01935.17 CBK20132.2 - 0.0076 16.4 3.7 0.25 11.4 0.0 3.2 3 0 0 3 3 3 1 Helicase HerA, central domain AAA_15 PF13175.6 CBK20132.2 - 0.011 15.5 6.1 0.82 9.3 0.0 2.8 3 0 0 3 3 2 0 AAA ATPase domain Mg_chelatase PF01078.21 CBK20132.2 - 0.012 15.0 0.0 1 8.7 0.0 2.5 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI Zeta_toxin PF06414.12 CBK20132.2 - 0.018 14.4 0.0 6.4 6.0 0.0 2.6 2 0 0 2 2 2 0 Zeta toxin NTPase_1 PF03266.15 CBK20132.2 - 0.023 14.6 0.2 6.4 6.7 0.0 3.0 3 0 0 3 3 2 0 NTPase DUF815 PF05673.13 CBK20132.2 - 0.026 13.7 0.0 1.9 7.6 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF815) NACHT PF05729.12 CBK20132.2 - 0.027 14.4 0.1 2.2 8.2 0.1 2.7 2 0 0 2 2 2 0 NACHT domain KAP_NTPase PF07693.14 CBK20132.2 - 0.028 13.7 0.0 0.8 8.9 0.0 2.7 2 0 0 2 2 2 0 KAP family P-loop domain MoaE PF02391.17 CBK20132.2 - 0.03 14.6 0.8 6.2 7.1 0.1 3.7 3 1 0 3 3 2 0 MoaE protein MoeA_C PF03454.15 CBK20132.2 - 0.032 14.4 0.0 3.8 7.8 0.1 3.3 3 0 0 3 3 2 0 MoeA C-terminal region (domain IV) AAA_14 PF13173.6 CBK20132.2 - 0.055 13.5 0.0 27 4.8 0.0 3.2 3 0 0 3 3 2 0 AAA domain APS_kinase PF01583.20 CBK20132.2 - 0.071 13.0 0.1 6.2 6.7 0.0 2.6 2 0 0 2 2 2 0 Adenylylsulphate kinase MCM PF00493.23 CBK20132.2 - 0.077 12.1 0.0 0.69 9.0 0.0 2.3 2 0 0 2 2 2 0 MCM P-loop domain MobB PF03205.14 CBK20132.2 - 0.078 12.9 0.1 5.2 7.0 0.1 2.7 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B ATP-synt_ab PF00006.25 CBK20132.2 - 0.1 12.2 0.1 5.7 6.5 0.0 2.4 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_19 PF13245.6 CBK20132.2 - 0.11 12.8 5.3 4.9 7.5 0.3 4.3 3 2 0 3 3 2 0 AAA domain CDC45 PF02724.14 CBK20132.2 - 0.12 10.7 3.8 0.19 10.0 3.8 1.2 1 0 0 1 1 1 0 CDC45-like protein AAA_28 PF13521.6 CBK20132.2 - 0.13 12.5 0.3 5.8 7.1 0.0 2.6 2 0 0 2 2 2 0 AAA domain T2SSE PF00437.20 CBK20132.2 - 0.37 9.8 2.9 0.78 8.7 0.1 2.5 3 0 0 3 3 2 0 Type II/IV secretion system protein AcetylCoA_hyd_C PF13336.6 CBK20133.2 - 3.1e-43 147.4 0.0 4.8e-43 146.8 0.0 1.3 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain AcetylCoA_hydro PF02550.15 CBK20133.2 - 1.1e-36 126.7 0.0 2.9e-36 125.3 0.0 1.7 2 0 0 2 2 2 1 Acetyl-CoA hydrolase/transferase N-terminal domain CoA_trans PF01144.23 CBK20133.2 - 0.085 12.2 0.1 0.27 10.6 0.0 1.8 2 0 0 2 2 2 0 Coenzyme A transferase Ribosomal_L19e PF01280.20 CBK20134.2 - 2.1e-57 193.2 11.9 2.7e-57 192.9 11.9 1.1 1 0 0 1 1 1 1 Ribosomal protein L19e Arm PF00514.23 CBK20135.2 - 1.4e-41 139.3 12.4 1.4e-12 47.2 0.2 8.5 8 0 0 8 8 8 8 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 CBK20135.2 - 2.5e-11 43.8 0.0 2e-07 31.3 0.0 4.2 4 0 0 4 4 4 1 HEAT-like repeat HEAT PF02985.22 CBK20135.2 - 0.00015 21.7 0.1 0.061 13.6 0.0 4.1 3 0 0 3 3 3 1 HEAT repeat HEAT_2 PF13646.6 CBK20135.2 - 0.0003 21.1 0.0 0.061 13.7 0.0 3.2 2 1 0 2 2 2 1 HEAT repeats Atx10homo_assoc PF09759.9 CBK20135.2 - 0.00076 19.5 0.3 0.13 12.3 0.1 3.2 3 0 0 3 3 3 1 Spinocerebellar ataxia type 10 protein domain Peptidase_A22B PF04258.13 CBK20136.2 - 9.6e-76 255.0 12.7 1.1e-75 254.8 12.7 1.0 1 0 0 1 1 1 1 Signal peptide peptidase SPP PF06550.11 CBK20136.2 - 3.6e-05 23.4 16.6 4.2e-05 23.2 10.0 2.6 1 1 1 2 2 2 2 Signal-peptide peptidase, presenilin aspartyl protease DUF5392 PF17370.2 CBK20136.2 - 1.3 9.1 4.5 1.9 8.6 0.1 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5392) UPF0016 PF01169.19 CBK20137.2 - 8.5e-36 122.1 24.7 1.4e-20 73.4 6.0 2.1 2 0 0 2 2 2 2 Uncharacterized protein family UPF0016 CRC_subunit PF08624.10 CBK20137.2 - 0.096 13.1 0.0 0.3 11.5 0.0 1.7 2 0 0 2 2 2 0 Chromatin remodelling complex Rsc7/Swp82 subunit IF4E PF01652.18 CBK20138.2 - 6.6e-44 149.5 0.1 8.1e-44 149.2 0.1 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E AAA PF00004.29 CBK20139.2 - 1.3e-39 135.7 0.0 2.3e-39 134.8 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CBK20139.2 - 7.3e-18 64.1 0.1 1.4e-17 63.2 0.1 1.4 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 CBK20139.2 - 3.1e-06 27.7 0.4 3.6e-05 24.2 0.1 2.5 2 1 0 2 2 2 1 AAA ATPase domain AAA_5 PF07728.14 CBK20139.2 - 7.1e-06 26.1 0.0 3.9e-05 23.7 0.0 2.4 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 CBK20139.2 - 4e-05 23.4 0.0 0.00012 21.9 0.0 1.8 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain TIP49 PF06068.13 CBK20139.2 - 0.00021 20.6 0.0 0.00041 19.7 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_22 PF13401.6 CBK20139.2 - 0.00056 20.2 0.0 0.26 11.5 0.0 3.0 1 1 2 3 3 3 1 AAA domain AAA_2 PF07724.14 CBK20139.2 - 0.00096 19.3 0.0 0.0028 17.8 0.0 1.7 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) RNA_helicase PF00910.22 CBK20139.2 - 0.0056 17.1 0.0 0.013 15.9 0.0 1.7 1 0 0 1 1 1 1 RNA helicase Vps4_C PF09336.10 CBK20139.2 - 0.024 14.7 0.2 0.074 13.1 0.0 1.9 2 0 0 2 2 2 0 Vps4 C terminal oligomerisation domain IstB_IS21 PF01695.17 CBK20139.2 - 0.033 13.9 0.0 0.13 12.0 0.0 2.0 3 0 0 3 3 3 0 IstB-like ATP binding protein Rad17 PF03215.15 CBK20139.2 - 0.041 13.8 0.0 0.071 13.0 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_18 PF13238.6 CBK20139.2 - 0.062 13.8 0.0 0.12 12.9 0.0 1.6 2 0 0 2 2 1 0 AAA domain AAA_33 PF13671.6 CBK20139.2 - 0.069 13.3 0.0 0.12 12.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 CBK20139.2 - 0.078 13.0 0.0 0.15 12.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 CBK20139.2 - 0.091 12.7 0.0 0.2 11.6 0.0 1.6 1 0 0 1 1 1 0 NACHT domain Mg_chelatase PF01078.21 CBK20139.2 - 0.12 11.7 0.1 0.29 10.5 0.0 1.6 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI MSA-2c PF12238.8 CBK20139.2 - 0.14 12.2 0.0 0.28 11.2 0.0 1.4 1 0 0 1 1 1 0 Merozoite surface antigen 2c AAA_3 PF07726.11 CBK20139.2 - 0.14 12.0 0.0 0.25 11.2 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) TsaE PF02367.17 CBK20139.2 - 0.16 11.9 0.0 0.65 10.0 0.0 1.9 1 1 1 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE SNARE PF05739.19 CBK20140.2 - 5.6e-08 32.6 0.1 1.6e-07 31.2 0.1 1.8 1 0 0 1 1 1 1 SNARE domain DUF812 PF05667.11 CBK20140.2 - 0.00034 19.7 13.5 0.00049 19.1 13.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF812) DUF948 PF06103.11 CBK20140.2 - 0.00036 20.7 12.4 0.12 12.6 3.0 3.4 3 1 1 4 4 4 3 Bacterial protein of unknown function (DUF948) TMPIT PF07851.13 CBK20140.2 - 0.0026 17.1 0.4 0.0026 17.1 0.4 2.3 2 0 0 2 2 2 1 TMPIT-like protein UPF0242 PF06785.11 CBK20140.2 - 0.0053 16.9 17.4 0.0076 16.4 1.0 2.2 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0242) N-terminus YkyA PF10368.9 CBK20140.2 - 0.0065 16.2 6.2 0.0065 16.2 6.2 2.5 2 1 0 2 2 2 1 Putative cell-wall binding lipoprotein CREPT PF16566.5 CBK20140.2 - 0.0095 16.1 2.2 0.0095 16.1 2.2 2.5 2 1 0 2 2 2 1 Cell-cycle alteration and expression-elevated protein in tumour DUF5089 PF17002.5 CBK20140.2 - 0.011 15.7 7.0 0.011 15.7 7.0 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF5089) UPF0184 PF03670.13 CBK20140.2 - 0.012 16.0 0.9 0.012 16.0 0.9 3.5 2 2 2 4 4 4 0 Uncharacterised protein family (UPF0184) Spc7 PF08317.11 CBK20140.2 - 0.013 14.4 1.8 0.013 14.4 1.8 2.5 2 1 0 2 2 2 0 Spc7 kinetochore protein FmiP_Thoc5 PF09766.9 CBK20140.2 - 0.076 12.3 9.4 0.22 10.8 0.5 2.4 2 1 0 2 2 2 0 Fms-interacting protein/Thoc5 SlyX PF04102.12 CBK20140.2 - 0.078 13.6 1.1 0.078 13.6 1.1 3.7 2 2 2 4 4 4 0 SlyX DDE_Tnp_1_2 PF13586.6 CBK20140.2 - 0.15 12.4 1.4 0.26 11.7 0.3 1.9 2 0 0 2 2 1 0 Transposase DDE domain Laminin_II PF06009.12 CBK20140.2 - 0.25 11.4 14.2 0.04 13.9 2.5 2.9 2 1 0 2 2 2 0 Laminin Domain II TssC PF17541.2 CBK20140.2 - 0.27 10.0 9.3 0.093 11.5 3.8 2.0 2 0 0 2 2 2 0 Type VI secretion system, TssC, VipB DASH_Duo1 PF08651.10 CBK20140.2 - 0.29 10.9 12.0 0.3 10.9 1.1 4.1 3 1 1 4 4 4 0 DASH complex subunit Duo1 Cluap1 PF10234.9 CBK20140.2 - 0.31 10.4 16.4 0.093 12.1 2.4 2.1 2 0 0 2 2 2 0 Clusterin-associated protein-1 KMP11 PF03037.16 CBK20140.2 - 0.39 11.5 9.4 1 10.2 1.0 2.7 2 1 0 2 2 2 0 Kinetoplastid membrane protein 11 IFT57 PF10498.9 CBK20140.2 - 0.39 9.6 19.8 0.71 8.8 3.0 2.3 2 0 0 2 2 2 0 Intra-flagellar transport protein 57 DUF1798 PF08807.10 CBK20140.2 - 0.63 10.2 6.2 1.2 9.3 2.4 2.3 2 0 0 2 2 2 0 Bacterial domain of unknown function (DUF1798) COG5 PF10392.9 CBK20140.2 - 0.69 10.1 6.9 1.8 8.8 0.4 2.6 2 1 0 2 2 2 0 Golgi transport complex subunit 5 NPV_P10 PF05531.12 CBK20140.2 - 0.86 10.1 13.1 0.4 11.2 3.2 3.2 3 1 0 3 3 3 0 Nucleopolyhedrovirus P10 protein Mgr1 PF08602.10 CBK20140.2 - 0.98 8.2 9.9 0.17 10.6 3.3 2.0 2 0 0 2 2 2 0 Mgr1-like, i-AAA protease complex subunit AIP3 PF03915.13 CBK20140.2 - 1 8.4 16.9 0.86 8.6 6.5 2.1 2 0 0 2 2 2 0 Actin interacting protein 3 MCU PF04678.13 CBK20140.2 - 1.4 9.0 11.6 2 8.5 0.1 2.6 2 1 1 3 3 3 0 Mitochondrial calcium uniporter HAUS-augmin3 PF14932.6 CBK20140.2 - 1.5 8.4 14.9 0.17 11.4 1.1 2.4 2 1 0 2 2 2 0 HAUS augmin-like complex subunit 3 HemX PF04375.14 CBK20140.2 - 1.5 8.0 11.2 0.19 11.0 0.9 2.2 2 0 0 2 2 2 0 HemX, putative uroporphyrinogen-III C-methyltransferase Sec34 PF04136.15 CBK20140.2 - 1.7 8.5 11.1 0.39 10.6 1.5 3.0 2 1 0 2 2 2 0 Sec34-like family T3SSipB PF16535.5 CBK20140.2 - 1.7 9.1 13.7 0.16 12.4 0.5 2.5 2 1 0 2 2 2 0 Type III cell invasion protein SipB ArsR PF09824.9 CBK20140.2 - 1.9 8.1 8.3 2.2 7.8 0.8 2.9 2 1 1 3 3 3 0 ArsR transcriptional regulator V_ATPase_I PF01496.19 CBK20140.2 - 2 6.2 12.4 0.94 7.3 0.9 2.0 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family DUF745 PF05335.13 CBK20140.2 - 2.6 7.7 15.5 0.026 14.3 3.3 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF745) Nup54 PF13874.6 CBK20140.2 - 2.8 8.1 16.8 2.9 8.0 2.2 3.3 2 1 1 3 3 3 0 Nucleoporin complex subunit 54 KxDL PF10241.9 CBK20140.2 - 3.2 8.1 24.2 2 8.7 2.0 4.2 2 2 2 4 4 4 0 Uncharacterized conserved protein Mod_r PF07200.13 CBK20140.2 - 3.3 7.8 17.5 5.2 7.2 7.8 2.5 2 1 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein LXG PF04740.12 CBK20140.2 - 4 7.1 19.2 5.2 6.7 4.4 2.7 2 2 0 2 2 2 0 LXG domain of WXG superfamily AKNA PF12443.8 CBK20140.2 - 5.3 7.8 12.8 12 6.6 1.7 3.8 2 2 2 4 4 4 0 AT-hook-containing transcription factor Methyltrn_RNA_4 PF09936.9 CBK20140.2 - 9.8 6.0 7.6 4.3 7.1 0.4 2.7 2 1 1 3 3 3 0 SAM-dependent RNA methyltransferase NESP55 PF06390.12 CBK20141.2 - 0.0091 15.6 8.7 0.0096 15.5 8.7 1.2 1 0 0 1 1 1 1 Neuroendocrine-specific golgi protein P55 (NESP55) DNA_pol_phi PF04931.13 CBK20141.2 - 1.5 6.8 9.3 1.6 6.7 9.3 1.1 1 0 0 1 1 1 0 DNA polymerase phi Presenilin PF01080.17 CBK20141.2 - 5.3 5.7 7.8 5.9 5.5 7.8 1.0 1 0 0 1 1 1 0 Presenilin CobT PF06213.12 CBK20141.2 - 7.5 5.9 11.5 8.6 5.7 11.5 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Trypan_PARP PF05887.11 CBK20141.2 - 7.5 6.5 16.3 12 5.9 16.3 1.5 1 1 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) RRN3 PF05327.11 CBK20142.2 - 7.8e-63 212.9 6.7 7.9e-61 206.3 6.7 2.0 1 1 0 1 1 1 1 RNA polymerase I specific transcription initiation factor RRN3 WD40 PF00400.32 CBK20143.2 - 7.5e-17 61.4 2.6 9.4e-06 26.3 0.1 5.6 5 0 0 5 5 5 3 WD domain, G-beta repeat Collagen PF01391.18 CBK20143.2 - 1.8e-06 27.6 9.0 3e-06 26.9 9.0 1.3 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) ANAPC4_WD40 PF12894.7 CBK20143.2 - 1.5e-05 25.2 0.1 0.022 15.1 0.0 3.9 2 1 4 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain Urm1 PF09138.11 CBK20144.2 - 9e-24 83.7 0.3 9.2e-24 83.6 0.3 1.0 1 0 0 1 1 1 1 Urm1 (Ubiquitin related modifier) ThiS PF02597.20 CBK20144.2 - 2.5e-05 24.8 0.1 3e-05 24.6 0.1 1.1 1 0 0 1 1 1 1 ThiS family RRP14 PF15459.6 CBK20145.2 - 7.6e-18 64.9 2.8 7.6e-18 64.9 2.8 2.6 3 0 0 3 3 3 1 60S ribosome biogenesis protein Rrp14 DUF1993 PF09351.10 CBK20145.2 - 0.1 12.7 2.1 0.14 12.3 2.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1993) DUF4735 PF15882.5 CBK20145.2 - 0.23 10.9 3.3 0.28 10.6 3.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4735) DUF1318 PF07027.12 CBK20145.2 - 0.82 10.1 7.7 0.38 11.2 1.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1318) Vps39_2 PF10367.9 CBK20145.2 - 2.7 8.5 5.8 25 5.4 1.7 2.2 1 1 1 2 2 2 0 Vacuolar sorting protein 39 domain 2 Rep-A_N PF04057.12 CBK20146.2 - 7.8e-10 38.7 0.3 1.2e-09 38.1 0.3 1.3 1 0 0 1 1 1 1 Replication factor-A protein 1, N-terminal domain tRNA_anti-codon PF01336.25 CBK20146.2 - 5.6e-06 26.3 0.0 1.1e-05 25.4 0.0 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain TFIIA PF03153.13 CBK20146.2 - 0.2 11.6 26.0 0.24 11.4 26.0 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SOG2 PF10428.9 CBK20146.2 - 1.1 8.4 12.4 1.3 8.1 12.4 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein PAT1 PF09770.9 CBK20146.2 - 4.3 5.5 24.3 5.5 5.1 24.3 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Rep_fac-A_C PF08646.10 CBK20147.2 - 3e-37 127.6 0.6 3.5e-37 127.4 0.6 1.0 1 0 0 1 1 1 1 Replication factor-A C terminal domain Ribosomal_L7Ae PF01248.26 CBK20148.2 - 3.9e-21 74.6 0.6 6.8e-21 73.8 0.6 1.4 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Efg1 PF10153.9 CBK20148.2 - 0.57 10.6 3.8 0.46 10.9 1.8 1.9 2 0 0 2 2 2 0 rRNA-processing protein Efg1 He_PIG PF05345.12 CBK20149.2 - 2.8e-06 27.4 6.3 0.0025 18.0 0.3 3.1 3 0 0 3 3 3 2 Putative Ig domain Pox_EPC_I2-L1 PF12575.8 CBK20149.2 - 0.17 12.1 1.0 0.51 10.6 1.0 1.8 1 0 0 1 1 1 0 Poxvirus entry protein complex L1 and I2 He_PIG PF05345.12 CBK20150.2 - 0.00096 19.3 0.2 0.0033 17.6 0.2 2.0 1 0 0 1 1 1 1 Putative Ig domain DUF2561 PF10812.8 CBK20150.2 - 0.0035 17.4 1.5 0.0051 16.9 0.4 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF2561) DUF898 PF05987.13 CBK20150.2 - 0.0084 15.2 0.1 0.015 14.4 0.1 1.3 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF898) EphA2_TM PF14575.6 CBK20150.2 - 0.067 14.1 0.6 0.13 13.2 0.6 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Myc_target_1 PF15179.6 CBK20150.2 - 0.28 11.1 1.3 3.6 7.5 0.3 2.2 2 0 0 2 2 2 0 Myc target protein 1 Synaptobrevin PF00957.21 CBK20150.2 - 0.39 10.5 8.3 0.77 9.6 8.3 1.5 1 0 0 1 1 1 0 Synaptobrevin DEAD PF00270.29 CBK20151.2 - 3.3e-40 137.7 0.3 5.2e-40 137.1 0.3 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CBK20151.2 - 2.4e-26 92.3 0.2 7e-25 87.5 0.0 2.5 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 CBK20151.2 - 2.8e-09 37.2 0.0 7.9e-09 35.7 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Astro_capsid_p PF12226.8 CBK20151.2 - 0.028 13.6 10.6 0.057 12.6 10.6 1.5 1 0 0 1 1 1 0 Turkey astrovirus capsid protein GRASP55_65 PF04495.14 CBK20151.2 - 0.16 12.3 0.3 0.43 10.9 0.1 1.8 2 0 0 2 2 2 0 GRASP55/65 PDZ-like domain Nop14 PF04147.12 CBK20151.2 - 0.28 9.4 11.4 0.059 11.6 8.1 1.5 2 0 0 2 2 2 0 Nop14-like family mRNA_triPase PF02940.15 CBK20152.2 - 3.7e-09 36.6 1.8 1e-08 35.2 1.8 1.8 1 1 0 1 1 1 1 mRNA capping enzyme, beta chain Nkap_C PF06047.11 CBK20152.2 - 0.024 14.7 0.0 0.06 13.5 0.0 1.6 1 1 0 1 1 1 0 NF-kappa-B-activating protein C-terminal domain Ribosomal_L3 PF00297.22 CBK20153.2 - 2.1e-19 69.8 4.5 2e-16 60.0 0.7 3.1 1 1 1 3 3 3 3 Ribosomal protein L3 MTS PF05175.14 CBK20154.2 - 0.00045 19.8 0.0 0.00059 19.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.6 CBK20154.2 - 0.073 13.8 0.0 0.11 13.3 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Sec16_C PF12931.7 CBK20155.2 - 3.5e-06 26.9 0.3 1.7e-05 24.6 0.3 2.0 1 1 0 1 1 1 1 Sec23-binding domain of Sec16 ANAPC4_WD40 PF12894.7 CBK20155.2 - 0.00048 20.4 2.0 1.4 9.3 0.2 3.4 1 1 2 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 CBK20155.2 - 0.002 18.9 4.6 0.027 15.3 0.0 4.1 4 0 0 4 4 4 1 WD domain, G-beta repeat DUF512 PF04459.12 CBK20155.2 - 0.059 12.6 0.0 0.16 11.2 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF512) Fe-S_biosyn PF01521.20 CBK20156.2 - 9e-13 48.4 0.0 1.2e-12 48.0 0.0 1.2 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis UPF0547 PF10571.9 CBK20156.2 - 0.043 13.9 0.2 0.11 12.5 0.2 1.8 1 0 0 1 1 1 0 Uncharacterised protein family UPF0547 EGF_alliinase PF04863.13 CBK20157.2 - 0.053 13.9 0.7 0.076 13.4 0.7 1.3 1 0 0 1 1 1 0 Alliinase EGF-like domain WD40 PF00400.32 CBK20158.2 - 3.9e-06 27.5 0.6 0.013 16.3 0.2 2.9 2 0 0 2 2 2 2 WD domain, G-beta repeat LisH_TPL PF17814.1 CBK20158.2 - 1.8e-05 24.3 0.1 3.7e-05 23.3 0.1 1.6 1 0 0 1 1 1 1 LisH-like dimerisation domain LisH PF08513.11 CBK20158.2 - 0.044 13.8 0.0 0.15 12.1 0.0 2.0 2 0 0 2 2 2 0 LisH Nucleoporin_N PF08801.11 CBK20158.2 - 0.052 12.3 0.0 2.3 6.9 0.0 2.1 1 1 1 2 2 2 0 Nup133 N terminal like DUF4082 PF13313.6 CBK20158.2 - 0.074 13.1 0.1 0.28 11.2 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4082) TFIID_NTD2 PF04494.15 CBK20158.2 - 0.12 12.6 0.6 0.21 11.8 0.1 1.6 2 0 0 2 2 2 0 WD40 associated region in TFIID subunit, NTD2 domain DASH_Dad2 PF08654.10 CBK20159.2 - 1.3e-08 35.1 0.2 1.3e-08 35.1 0.2 1.0 1 0 0 1 1 1 1 DASH complex subunit Dad2 Histone PF00125.24 CBK20160.2 - 4.5e-20 72.4 0.2 5.5e-20 72.1 0.2 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 CBK20160.2 - 1.8e-05 24.9 0.2 3.7e-05 23.9 0.0 1.5 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone_H2A_C PF16211.5 CBK20161.2 - 3.3e-15 55.5 0.0 5.5e-15 54.8 0.0 1.4 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 CBK20161.2 - 2.4e-13 50.6 0.0 4e-13 49.8 0.0 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 CBK20161.2 - 1.4e-05 25.2 0.0 2e-05 24.8 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone GDP_Man_Dehyd PF16363.5 CBK20162.2 - 7.4e-47 160.4 0.0 8.7e-47 160.1 0.0 1.0 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 CBK20162.2 - 1.5e-42 145.7 0.0 1.8e-42 145.5 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 CBK20162.2 - 1.5e-09 37.5 0.0 8.1e-08 31.7 0.0 2.7 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.19 CBK20162.2 - 2.3e-09 36.7 0.0 3.1e-09 36.2 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 CBK20162.2 - 6.7e-06 26.1 0.0 1.2e-05 25.3 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding adh_short PF00106.25 CBK20162.2 - 1.5e-05 24.5 0.0 2.6e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase RmlD_sub_bind PF04321.17 CBK20162.2 - 6.5e-05 22.2 0.0 9.4e-05 21.6 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 CBK20162.2 - 0.00016 20.9 0.2 0.0016 17.6 0.2 2.3 1 1 0 1 1 1 1 Male sterility protein KR PF08659.10 CBK20162.2 - 0.0011 18.9 0.0 0.0043 17.0 0.0 1.8 1 1 0 1 1 1 1 KR domain NmrA PF05368.13 CBK20162.2 - 0.017 14.7 0.0 0.074 12.6 0.0 1.9 2 0 0 2 2 2 0 NmrA-like family adh_short_C2 PF13561.6 CBK20162.2 - 0.084 12.4 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase UQ_con PF00179.26 CBK20163.2 - 1.9e-52 176.6 0.0 2.1e-52 176.5 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 CBK20163.2 - 0.031 14.0 0.0 0.039 13.7 0.0 1.2 1 0 0 1 1 1 0 Prokaryotic E2 family B RWD PF05773.22 CBK20163.2 - 0.037 14.3 0.0 0.047 14.0 0.0 1.3 1 0 0 1 1 1 0 RWD domain UEV PF05743.13 CBK20163.2 - 0.11 12.4 0.0 0.17 11.8 0.0 1.3 1 0 0 1 1 1 0 UEV domain WAPL PF07814.13 CBK20165.2 - 0.013 14.3 0.0 0.022 13.5 0.0 1.5 1 0 0 1 1 1 0 Wings apart-like protein regulation of heterochromatin ACT_7 PF13840.6 CBK20165.2 - 0.022 14.6 0.9 6.6 6.6 0.0 2.9 2 0 0 2 2 2 0 ACT domain Arm PF00514.23 CBK20165.2 - 0.25 11.4 0.1 0.25 11.4 0.1 2.9 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat Cpn60_TCP1 PF00118.24 CBK20166.2 - 5.1e-135 450.9 2.5 5.7e-135 450.7 2.5 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family ARPC4 PF05856.12 CBK20167.2 - 3.1e-54 183.1 1.0 3.6e-54 182.8 1.0 1.1 1 0 0 1 1 1 1 ARP2/3 complex 20 kDa subunit (ARPC4) DnaJ PF00226.31 CBK20168.2 - 9.5e-15 54.5 0.0 2.6e-14 53.1 0.0 1.8 1 0 0 1 1 1 1 DnaJ domain GYF_2 PF14237.6 CBK20168.2 - 0.00053 19.7 0.0 0.0013 18.5 0.0 1.7 1 0 0 1 1 1 1 GYF domain 2 DUF3425 PF11905.8 CBK20168.2 - 0.0079 16.2 0.7 0.19 11.7 0.7 2.8 1 1 0 1 1 1 1 Domain of unknown function (DUF3425) MRVI1 PF05781.12 CBK20168.2 - 0.049 12.3 0.0 0.099 11.3 0.0 1.4 1 0 0 1 1 1 0 MRVI1 protein zf-DNL PF05180.12 CBK20169.2 - 1.6e-30 104.8 0.7 2.2e-30 104.4 0.7 1.2 1 0 0 1 1 1 1 DNL zinc finger NLBH PF05211.12 CBK20169.2 - 0.0036 16.9 0.0 0.0048 16.5 0.0 1.1 1 0 0 1 1 1 1 Neuraminyllactose-binding hemagglutinin precursor (NLBH) HNH_5 PF14279.6 CBK20169.2 - 0.048 13.5 0.7 0.09 12.7 0.0 1.8 2 0 0 2 2 2 0 HNH endonuclease RNA_pol_Rpb2_2 PF04561.14 CBK20169.2 - 0.094 12.3 0.0 0.1 12.2 0.0 1.2 1 0 0 1 1 1 0 RNA polymerase Rpb2, domain 2 zf-ZPR1 PF03367.13 CBK20169.2 - 0.25 11.2 3.0 0.55 10.1 0.9 2.1 1 1 0 2 2 2 0 ZPR1 zinc-finger domain GDE_C PF06202.14 CBK20170.2 - 9.6e-85 284.8 0.1 1.7e-84 284.0 0.1 1.3 1 0 0 1 1 1 1 Amylo-alpha-1,6-glucosidase hGDE_central PF14702.6 CBK20170.2 - 1.1e-30 107.2 1.0 1.3e-14 54.5 0.3 2.2 2 0 0 2 2 2 2 Central domain of human glycogen debranching enzyme hDGE_amylase PF14701.6 CBK20170.2 - 9.7e-22 77.6 0.0 1.5e-21 77.0 0.0 1.2 1 0 0 1 1 1 1 Glycogen debranching enzyme, glucanotransferase domain Glyco_hydro_100 PF12899.7 CBK20170.2 - 0.062 12.0 2.1 3.1 6.4 0.1 2.3 2 0 0 2 2 2 0 Alkaline and neutral invertase V-ATPase_H_C PF11698.8 CBK20171.2 - 3.4e-05 23.9 2.0 0.00015 21.9 0.2 2.3 2 0 0 2 2 2 1 V-ATPase subunit H DUF3361 PF11841.8 CBK20171.2 - 7.4e-05 22.7 2.6 0.034 14.1 0.2 2.2 1 1 1 2 2 2 2 Domain of unknown function (DUF3361) Fes1 PF08609.10 CBK20171.2 - 0.00029 21.6 1.7 0.018 15.9 0.4 2.6 2 0 0 2 2 2 1 Nucleotide exchange factor Fes1 Arm PF00514.23 CBK20171.2 - 0.0016 18.4 4.6 2.7 8.2 0.0 4.1 5 0 0 5 5 5 2 Armadillo/beta-catenin-like repeat HEAT PF02985.22 CBK20171.2 - 0.0017 18.5 0.5 1.9 8.9 0.0 3.7 4 0 0 4 4 3 1 HEAT repeat DRIM PF07539.12 CBK20171.2 - 0.0019 16.6 0.2 0.0019 16.6 0.2 2.0 1 1 1 2 2 2 1 Down-regulated in metastasis HEAT_2 PF13646.6 CBK20171.2 - 0.0039 17.5 0.1 0.035 14.5 0.0 2.5 2 1 1 3 3 3 1 HEAT repeats DUF913 PF06025.12 CBK20171.2 - 0.016 14.2 0.4 0.083 11.9 0.4 2.3 1 1 0 1 1 1 0 Domain of Unknown Function (DUF913) FPL PF09758.9 CBK20171.2 - 0.026 14.6 1.5 0.047 13.7 0.5 2.0 1 1 1 2 2 2 0 Uncharacterised conserved protein RICTOR_V PF14668.6 CBK20171.2 - 0.043 14.0 0.0 0.78 10.0 0.0 2.8 1 1 2 3 3 3 0 Rapamycin-insensitive companion of mTOR, domain 5 Atx10homo_assoc PF09759.9 CBK20171.2 - 0.065 13.3 0.4 0.93 9.6 0.1 2.4 2 0 0 2 2 2 0 Spinocerebellar ataxia type 10 protein domain UNC45-central PF11701.8 CBK20171.2 - 0.12 12.3 2.2 4.6 7.2 1.1 2.8 2 1 0 2 2 2 0 Myosin-binding striated muscle assembly central Clat_adaptor_s PF01217.20 CBK20173.2 - 7.4e-35 119.9 3.9 8.3e-35 119.8 3.9 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain ATG16 PF08614.11 CBK20174.2 - 0.024 14.9 40.8 0.071 13.3 26.0 2.8 2 1 0 2 2 2 0 Autophagy protein 16 (ATG16) HALZ PF02183.18 CBK20174.2 - 0.048 13.9 1.1 0.048 13.9 1.1 5.2 5 0 0 5 5 5 0 Homeobox associated leucine zipper Jnk-SapK_ap_N PF09744.9 CBK20174.2 - 0.12 12.6 39.4 4.9 7.3 4.3 3.6 2 1 0 2 2 2 0 JNK_SAPK-associated protein-1 MtrB PF05440.12 CBK20174.2 - 0.34 11.3 1.3 30 5.1 0.2 2.6 2 0 0 2 2 2 0 Tetrahydromethanopterin S-methyltransferase subunit B PIN_9 PF18477.1 CBK20174.2 - 0.47 10.8 8.1 0.095 13.0 3.0 2.2 2 0 0 2 2 2 0 PIN like domain ADIP PF11559.8 CBK20174.2 - 0.59 10.2 46.5 3.4 7.7 10.1 3.7 2 2 2 4 4 4 0 Afadin- and alpha -actinin-Binding DUF812 PF05667.11 CBK20174.2 - 0.7 8.7 37.2 9.4 5.0 36.7 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF812) FPP PF05911.11 CBK20174.2 - 0.79 7.8 36.8 0.37 8.9 16.3 2.8 1 1 2 3 3 3 0 Filament-like plant protein, long coiled-coil DUF4201 PF13870.6 CBK20174.2 - 1.2 8.8 39.3 0.29 10.8 1.8 3.5 2 1 1 3 3 3 0 Domain of unknown function (DUF4201) UPF0242 PF06785.11 CBK20174.2 - 1.2 9.2 43.9 0.078 13.1 6.9 3.3 2 1 1 3 3 3 0 Uncharacterised protein family (UPF0242) N-terminus IFT20 PF14931.6 CBK20174.2 - 1.5 9.0 34.1 0.044 14.0 6.2 4.0 2 2 1 3 3 3 0 Intraflagellar transport complex B, subunit 20 CENP-F_leu_zip PF10473.9 CBK20174.2 - 1.9 8.5 43.7 0.099 12.7 9.6 4.3 2 1 2 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 GrpE PF01025.19 CBK20174.2 - 3.5 7.2 28.7 2.4 7.8 1.3 4.2 2 1 1 4 4 4 0 GrpE DUF724 PF05266.14 CBK20174.2 - 3.8 7.3 26.1 0.81 9.5 13.6 3.0 2 1 0 2 2 2 0 Protein of unknown function (DUF724) LPP PF04728.13 CBK20174.2 - 5.9 7.4 9.3 9 6.8 1.1 3.6 3 1 0 3 3 3 0 Lipoprotein leucine-zipper FlaC_arch PF05377.11 CBK20174.2 - 7.5 7.0 17.2 22 5.5 0.3 4.3 4 1 0 4 4 4 0 Flagella accessory protein C (FlaC) RRM_2 PF04059.12 CBK20175.2 - 0.17 12.1 0.0 0.29 11.4 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif 2 Macoilin PF09726.9 CBK20175.2 - 1.7 7.1 4.9 1.9 6.9 4.9 1.1 1 0 0 1 1 1 0 Macoilin family Ribosomal_S8e PF01201.22 CBK20176.2 - 3.4e-35 121.2 0.1 4.4e-35 120.8 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein S8e ECH_2 PF16113.5 CBK20177.2 - 3.7e-28 99.0 0.0 4.6e-28 98.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_1 PF00378.20 CBK20177.2 - 4.8e-06 26.1 0.0 6.8e-06 25.6 0.0 1.3 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase zf-RING_4 PF14570.6 CBK20178.2 - 1.6e-18 66.2 16.8 4.1e-18 64.9 16.8 1.7 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-C3HC4_3 PF13920.6 CBK20178.2 - 2.3e-05 24.2 12.3 2.3e-05 24.2 12.3 2.3 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CBK20178.2 - 0.0015 18.8 14.2 0.0049 17.2 14.2 1.9 1 0 0 1 1 1 1 Ring finger domain Prok-RING_4 PF14447.6 CBK20178.2 - 0.0059 16.4 3.7 0.0059 16.4 3.7 2.8 2 1 1 3 3 3 1 Prokaryotic RING finger family 4 RRM_1 PF00076.22 CBK20178.2 - 0.0082 15.9 0.0 0.38 10.6 0.0 2.5 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Rad50_zn_hook PF04423.14 CBK20178.2 - 0.7 9.8 4.1 1.4 8.8 0.2 2.5 2 0 0 2 2 2 0 Rad50 zinc hook motif zf-RING_5 PF14634.6 CBK20178.2 - 0.8 9.7 15.2 1 9.4 12.1 2.5 2 0 0 2 2 2 0 zinc-RING finger domain DZR PF12773.7 CBK20178.2 - 2 8.5 11.6 46 4.2 10.0 3.0 2 1 0 2 2 2 0 Double zinc ribbon MORN PF02493.20 CBK20180.2 - 1.7e-08 33.8 17.6 0.0017 18.1 0.1 6.3 7 1 0 7 7 7 3 MORN repeat Nucleotid_trans PF03407.16 CBK20181.2 - 8e-30 104.4 0.1 1.3e-29 103.8 0.1 1.2 1 0 0 1 1 1 1 Nucleotide-diphospho-sugar transferase DUF4860 PF16152.5 CBK20181.2 - 0.092 12.6 0.0 0.22 11.4 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4860) Aminotran_1_2 PF00155.21 CBK20182.2 - 1.3e-90 304.2 0.0 1.5e-90 304.0 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II GHMP_kinases_N PF00288.26 CBK20183.2 - 1.6e-08 34.7 0.0 3.1e-08 33.7 0.0 1.5 1 0 0 1 1 1 1 GHMP kinases N terminal domain Myb_DNA-binding PF00249.31 CBK20184.2 - 5.8e-28 96.8 9.7 4.7e-15 55.5 0.8 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 CBK20184.2 - 5e-22 77.9 7.8 1e-14 54.5 0.7 3.0 2 1 1 3 3 3 2 Myb-like DNA-binding domain SLIDE PF09111.10 CBK20184.2 - 8.6e-05 22.5 0.1 0.006 16.6 0.0 2.6 1 1 1 2 2 2 1 SLIDE Myb_DNA-bind_4 PF13837.6 CBK20184.2 - 0.0049 17.2 10.0 0.0097 16.3 1.8 3.0 2 1 0 2 2 2 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 CBK20184.2 - 0.036 14.4 3.6 0.49 10.7 0.7 2.6 2 0 0 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_3 PF12776.7 CBK20184.2 - 0.17 12.8 3.8 9.6 7.3 0.1 2.9 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain Connexin43 PF03508.13 CBK20184.2 - 1.5 8.5 3.4 0.95 9.1 0.3 2.3 2 0 0 2 2 2 0 Gap junction alpha-1 protein (Cx43) Myb_DNA-bind_5 PF13873.6 CBK20184.2 - 6.3 7.0 10.3 2.7 8.2 0.2 3.2 3 1 0 3 3 3 0 Myb/SANT-like DNA-binding domain PAP_assoc PF03828.19 CBK20185.2 - 3e-15 56.2 0.5 5.8e-15 55.3 0.5 1.5 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 CBK20185.2 - 0.0014 18.9 0.0 0.003 17.8 0.0 1.6 1 0 0 1 1 1 1 Nucleotidyltransferase domain Polbeta PF18765.1 CBK20185.2 - 0.019 15.0 1.1 0.055 13.6 0.1 2.0 2 0 0 2 2 2 0 Polymerase beta, Nucleotidyltransferase PRP38 PF03371.15 CBK20187.2 - 8.9e-55 185.2 0.3 1.3e-54 184.7 0.0 1.4 2 0 0 2 2 2 1 PRP38 family TPR_2 PF07719.17 CBK20188.2 - 0.0057 16.7 0.0 0.99 9.7 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 CBK20188.2 - 0.0078 16.9 2.0 0.19 12.6 0.0 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 CBK20188.2 - 0.05 14.1 0.1 0.14 12.6 0.1 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat DUF4366 PF14283.6 CBK20188.2 - 2.1 8.4 4.3 30 4.6 2.5 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF4366) zinc_ribbon_6 PF14599.6 CBK20190.2 - 3.2e-14 52.7 0.2 3.2e-14 52.7 0.2 1.4 2 0 0 2 2 1 1 Zinc-ribbon zf-RING_2 PF13639.6 CBK20190.2 - 1.6e-06 28.3 1.4 1.6e-06 28.3 1.4 2.3 2 1 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.7 CBK20190.2 - 8.1e-06 26.0 1.1 8.1e-06 26.0 1.1 1.9 3 0 0 3 3 2 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 CBK20190.2 - 1.3e-05 24.9 5.5 2.2e-05 24.2 1.4 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CBK20190.2 - 2.8e-05 24.0 7.2 3.9e-05 23.5 1.7 2.2 2 0 0 2 2 2 1 zinc-RING finger domain Prok-RING_4 PF14447.6 CBK20190.2 - 0.00016 21.5 2.2 0.0004 20.2 0.3 2.0 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 CBK20190.2 - 0.00019 21.3 2.4 0.00019 21.3 2.4 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 CBK20190.2 - 0.00026 20.8 5.0 0.00031 20.5 0.8 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C2H2 PF00096.26 CBK20190.2 - 0.0053 17.2 0.9 2.9 8.5 0.5 2.5 2 0 0 2 2 2 1 Zinc finger, C2H2 type PHD PF00628.29 CBK20190.2 - 0.0066 16.3 4.0 0.11 12.4 1.5 2.4 2 0 0 2 2 2 1 PHD-finger zinc_ribbon_16 PF17034.5 CBK20190.2 - 0.0095 16.1 2.2 0.011 15.9 0.3 1.9 1 1 0 1 1 1 1 Zinc-ribbon like family DZR PF12773.7 CBK20190.2 - 0.014 15.4 0.9 0.037 14.1 0.9 1.8 1 1 0 1 1 1 0 Double zinc ribbon Zn_ribbon_17 PF17120.5 CBK20190.2 - 0.015 14.9 3.4 0.029 14.0 1.1 2.4 2 1 0 2 2 2 0 Zinc-ribbon, C4HC2 type TackOD1 PF18551.1 CBK20190.2 - 0.018 14.7 0.8 0.023 14.4 0.8 1.2 1 0 0 1 1 1 0 Thaumarchaeal output domain 1 CpXC PF14353.6 CBK20190.2 - 0.061 13.4 1.1 0.6 10.2 0.1 2.0 2 0 0 2 2 2 0 CpXC protein zf-RING-like PF08746.11 CBK20190.2 - 0.12 12.7 1.0 0.12 12.7 1.0 2.0 2 0 0 2 2 2 0 RING-like domain FANCL_C PF11793.8 CBK20190.2 - 0.16 12.2 4.0 0.5 10.6 1.3 2.5 2 1 0 2 2 2 0 FANCL C-terminal domain zf-RING_UBOX PF13445.6 CBK20190.2 - 0.32 11.1 7.9 0.11 12.6 2.7 2.6 2 1 0 2 2 2 0 RING-type zinc-finger zf_UBZ PF18439.1 CBK20190.2 - 0.51 10.0 5.4 0.89 9.2 0.0 2.6 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger zf-C3HC4_4 PF15227.6 CBK20190.2 - 0.58 10.4 6.0 0.31 11.2 2.3 2.1 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-C3H2C3 PF17122.5 CBK20190.2 - 0.69 10.0 8.2 2.2 8.4 2.8 2.5 2 1 0 2 2 2 0 Zinc-finger Peptidase_M48 PF01435.18 CBK20191.2 - 8.8e-37 126.8 0.2 8.8e-37 126.8 0.2 1.5 2 0 0 2 2 2 1 Peptidase family M48 Peptidase_M48_N PF16491.5 CBK20191.2 - 5.1e-18 65.6 3.6 5.1e-18 65.6 3.6 1.6 2 0 0 2 2 2 1 CAAX prenyl protease N-terminal, five membrane helices DAGK_prokar PF01219.19 CBK20191.2 - 0.026 14.4 0.1 0.026 14.4 0.1 2.3 2 0 0 2 2 2 0 Prokaryotic diacylglycerol kinase SprT-like PF10263.9 CBK20191.2 - 0.064 13.1 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 SprT-like family Peptidase_M56 PF05569.11 CBK20191.2 - 0.11 11.7 6.4 0.59 9.3 0.1 2.4 1 1 1 2 2 2 0 BlaR1 peptidase M56 PK PF00224.21 CBK20192.2 - 2.8e-128 427.7 2.6 7e-128 426.4 0.6 2.0 1 1 1 2 2 2 1 Pyruvate kinase, barrel domain PK_C PF02887.16 CBK20192.2 - 6.3e-11 42.5 0.5 1.4e-10 41.4 0.5 1.6 1 0 0 1 1 1 1 Pyruvate kinase, alpha/beta domain COMM_domain PF07258.14 CBK20192.2 - 1.5e-08 34.6 0.0 3.9e-08 33.3 0.0 1.7 1 0 0 1 1 1 1 COMM domain HpcH_HpaI PF03328.14 CBK20192.2 - 0.006 15.7 0.0 0.012 14.8 0.0 1.5 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family MIT PF04212.18 CBK20193.2 - 0.0002 21.3 0.0 0.00045 20.2 0.0 1.6 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain Ribosomal_L27e PF01777.18 CBK20194.2 - 8.4e-22 77.3 7.5 8.4e-22 77.3 7.5 1.7 2 0 0 2 2 2 1 Ribosomal L27e protein family KOW PF00467.29 CBK20194.2 - 4.2e-06 26.5 0.3 7.6e-06 25.7 0.3 1.5 1 0 0 1 1 1 1 KOW motif DUF974 PF06159.13 CBK20195.2 - 1.4e-08 34.8 0.0 2e-08 34.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF974) LRR_4 PF12799.7 CBK20196.2 - 3.1e-05 24.2 4.2 0.073 13.5 1.1 3.6 2 1 2 4 4 4 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CBK20196.2 - 0.00012 21.8 5.7 0.0002 21.1 1.0 3.0 3 0 0 3 3 3 1 Leucine rich repeat DUF3915 PF13054.6 CBK20196.2 - 0.091 12.7 0.0 0.19 11.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3915) NUC129 PF08157.11 CBK20196.2 - 0.12 12.8 0.0 0.3 11.5 0.0 1.6 1 0 0 1 1 1 0 NUC129 domain LRR_1 PF00560.33 CBK20196.2 - 0.35 11.6 3.5 37 5.4 0.1 4.8 5 1 0 5 5 5 0 Leucine Rich Repeat LRR_4 PF12799.7 CBK20197.2 - 2.1e-15 56.5 21.8 1.4e-06 28.6 2.6 4.6 4 0 0 4 4 4 4 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 CBK20197.2 - 1.9e-10 40.5 0.7 1e-05 25.1 0.0 2.7 2 1 1 3 3 3 3 Leucine-rich repeat LRR_8 PF13855.6 CBK20197.2 - 4e-09 36.1 27.5 3.1e-07 30.1 8.0 4.8 2 1 1 4 4 4 3 Leucine rich repeat LRR_6 PF13516.6 CBK20197.2 - 1.3e-06 27.9 19.4 0.063 13.4 0.4 7.0 7 0 0 7 7 7 3 Leucine Rich repeat LRR_1 PF00560.33 CBK20197.2 - 0.0034 17.7 21.2 1 10.2 0.2 6.7 5 2 0 5 5 5 2 Leucine Rich Repeat CbiQ PF02361.16 CBK20197.2 - 0.13 11.9 0.6 0.16 11.5 0.6 1.1 1 0 0 1 1 1 0 Cobalt transport protein LRR_2 PF07723.13 CBK20197.2 - 1.3 9.8 7.3 94 3.9 0.1 4.9 5 0 0 5 5 5 0 Leucine Rich Repeat HSP70 PF00012.20 CBK20198.2 - 2.3e-35 121.9 0.2 8.5e-34 116.7 0.2 2.0 1 1 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 CBK20198.2 - 9.4e-08 31.2 0.0 2.4e-06 26.6 0.0 2.7 2 1 0 2 2 2 1 MreB/Mbl protein DDR PF08841.10 CBK20198.2 - 0.047 12.7 0.0 0.18 10.8 0.0 1.8 2 0 0 2 2 2 0 Diol dehydratase reactivase ATPase-like domain MutL PF13941.6 CBK20198.2 - 0.071 11.7 0.1 0.21 10.1 0.0 1.7 2 0 0 2 2 2 0 MutL protein FtsA PF14450.6 CBK20198.2 - 0.19 12.1 1.6 7.9 7.0 0.4 3.5 3 2 0 3 3 3 0 Cell division protein FtsA Glyco_transf_49 PF13896.6 CBK20200.2 - 0.0001 21.8 2.3 0.00011 21.7 2.3 1.1 1 0 0 1 1 1 1 Glycosyl-transferase for dystroglycan GrpB PF04229.14 CBK20200.2 - 0.075 13.2 0.1 0.099 12.8 0.1 1.3 1 0 0 1 1 1 0 GrpB protein Clathrin_lg_ch PF01086.17 CBK20202.2 - 1.3e-20 74.4 18.5 1.6e-20 74.1 18.5 1.1 1 0 0 1 1 1 1 Clathrin light chain GCIP PF13324.6 CBK20202.2 - 0.74 9.4 6.8 1.1 8.8 6.8 1.2 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting MORN PF02493.20 CBK20203.2 - 4.6e-56 183.5 114.4 4.7e-05 23.0 0.3 19.0 19 0 0 19 19 19 18 MORN repeat HSP70 PF00012.20 CBK20203.2 - 1.7e-23 82.7 0.0 3e-23 81.9 0.0 1.3 1 0 0 1 1 1 1 Hsp70 protein SGL PF08450.12 CBK20203.2 - 0.095 12.3 0.3 0.22 11.0 0.3 1.6 1 0 0 1 1 1 0 SMP-30/Gluconolactonase/LRE-like region Filament PF00038.21 CBK20204.2 - 0.00014 21.6 33.1 0.00014 21.6 33.1 3.0 1 1 1 2 2 2 1 Intermediate filament protein KASH_CCD PF14662.6 CBK20204.2 - 0.00054 19.8 0.8 0.00054 19.8 0.8 5.6 1 1 3 4 4 3 2 Coiled-coil region of CCDC155 or KASH ATG16 PF08614.11 CBK20204.2 - 0.00057 20.2 106.3 0.26 11.5 11.4 6.1 1 1 6 7 7 7 3 Autophagy protein 16 (ATG16) ADIP PF11559.8 CBK20204.2 - 0.00069 19.7 97.2 0.0091 16.1 12.1 6.5 2 2 5 7 7 7 3 Afadin- and alpha -actinin-Binding Lebercilin PF15619.6 CBK20204.2 - 0.00071 19.3 7.7 0.00071 19.3 7.7 4.8 1 1 2 4 4 4 1 Ciliary protein causing Leber congenital amaurosis disease SHE3 PF17078.5 CBK20204.2 - 0.0077 16.0 7.4 0.0077 16.0 7.4 6.0 1 1 2 4 4 4 1 SWI5-dependent HO expression protein 3 TMF_DNA_bd PF12329.8 CBK20204.2 - 0.0093 15.9 17.0 0.0093 15.9 17.0 9.2 3 2 6 9 9 9 1 TATA element modulatory factor 1 DNA binding TolA_bind_tri PF16331.5 CBK20204.2 - 0.014 15.5 3.6 0.014 15.5 3.6 8.1 4 2 3 7 7 6 0 TolA binding protein trimerisation DUF745 PF05335.13 CBK20204.2 - 0.17 11.6 72.8 1.2 8.8 21.2 5.3 2 1 1 4 4 4 0 Protein of unknown function (DUF745) GAS PF13851.6 CBK20204.2 - 1 8.7 104.0 0.16 11.3 21.5 5.3 1 1 3 5 5 5 0 Growth-arrest specific micro-tubule binding Golgin_A5 PF09787.9 CBK20204.2 - 3.7 6.9 105.3 0.15 11.5 28.4 4.1 1 1 3 4 4 4 0 Golgin subfamily A member 5 Spc7 PF08317.11 CBK20204.2 - 4 6.2 107.5 2 7.2 21.1 5.2 1 1 4 5 5 5 0 Spc7 kinetochore protein DUF4407 PF14362.6 CBK20204.2 - 4.5 6.5 73.7 0.067 12.5 18.7 4.2 1 1 3 4 4 4 0 Domain of unknown function (DUF4407) Ribosomal_L4 PF00573.22 CBK20205.2 - 1.7e-39 135.5 0.1 3.2e-39 134.6 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Ribos_L4_asso_C PF14374.6 CBK20205.2 - 1e-22 80.0 1.6 4.2e-22 78.0 1.5 2.1 2 0 0 2 2 2 1 60S ribosomal protein L4 C-terminal domain Ribonuc_P_40 PF08584.11 CBK20205.2 - 0.051 12.8 0.0 0.11 11.8 0.0 1.4 1 0 0 1 1 1 0 Ribonuclease P 40kDa (Rpp40) subunit Ribosomal_L2_C PF03947.18 CBK20206.2 - 1.4e-45 154.6 1.6 2.1e-45 154.0 1.6 1.2 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 CBK20206.2 - 1.2e-14 54.0 0.1 3.4e-14 52.6 0.0 1.9 2 0 0 2 2 2 1 Ribosomal Proteins L2, RNA binding domain HSP70 PF00012.20 CBK20207.2 - 3.9e-198 659.4 4.8 4.7e-198 659.2 4.8 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 CBK20207.2 - 3e-21 75.6 0.0 2.6e-17 62.6 0.0 2.3 2 0 0 2 2 2 2 MreB/Mbl protein FtsA PF14450.6 CBK20207.2 - 0.00098 19.5 1.8 1.1 9.8 0.1 3.5 3 2 0 3 3 3 2 Cell division protein FtsA DUF4852 PF16144.5 CBK20207.2 - 0.0021 18.2 1.0 0.0074 16.4 0.1 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF4852) Hydantoinase_A PF01968.18 CBK20207.2 - 0.006 15.9 0.3 0.058 12.6 0.0 2.2 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase DUF4524 PF15025.6 CBK20207.2 - 0.1 12.3 0.2 0.69 9.6 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4524) Vps53_N PF04100.12 CBK20208.2 - 9.3e-70 235.5 9.3 2.4e-68 230.8 9.3 2.0 1 1 0 1 1 1 1 Vps53-like, N-terminal Vps54_N PF10475.9 CBK20208.2 - 0.00045 19.6 5.2 0.00045 19.6 5.2 1.5 2 0 0 2 2 2 1 Vacuolar-sorting protein 54, of GARP complex Laminin_II PF06009.12 CBK20208.2 - 0.0011 19.0 3.6 0.0011 19.0 3.6 2.0 1 1 1 2 2 2 1 Laminin Domain II XhlA PF10779.9 CBK20208.2 - 0.015 15.5 8.8 0.023 14.9 2.8 3.4 3 0 0 3 3 3 0 Haemolysin XhlA DUF2884 PF11101.8 CBK20208.2 - 0.096 12.2 7.2 0.032 13.7 4.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2884) PRT_C PF08372.10 CBK20208.2 - 0.11 12.2 0.2 0.19 11.5 0.2 1.4 1 0 0 1 1 1 0 Plant phosphoribosyltransferase C-terminal Laminin_I PF06008.14 CBK20208.2 - 0.15 11.7 9.4 0.028 14.2 5.4 1.9 2 0 0 2 2 2 0 Laminin Domain I SKA2 PF16740.5 CBK20208.2 - 0.26 11.1 7.6 4.7 7.0 2.5 3.8 2 1 2 4 4 4 0 Spindle and kinetochore-associated protein 2 ING PF12998.7 CBK20208.2 - 0.34 11.5 5.0 0.92 10.1 5.0 1.8 1 0 0 1 1 1 0 Inhibitor of growth proteins N-terminal histone-binding Sec5 PF15469.6 CBK20208.2 - 0.38 10.5 4.2 0.85 9.4 4.2 1.7 1 1 0 1 1 1 0 Exocyst complex component Sec5 Leu_zip PF15294.6 CBK20208.2 - 0.56 9.7 9.0 0.064 12.8 4.5 1.8 2 0 0 2 2 2 0 Leucine zipper DUF948 PF06103.11 CBK20208.2 - 0.63 10.3 3.3 1 9.7 1.2 2.4 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) Atg14 PF10186.9 CBK20208.2 - 0.88 8.6 6.3 1.5 7.8 6.3 1.4 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Spc7 PF08317.11 CBK20208.2 - 1 8.2 14.9 0.015 14.2 7.7 1.6 2 0 0 2 2 2 0 Spc7 kinetochore protein DUF1664 PF07889.12 CBK20208.2 - 1.7 8.7 5.7 12 5.9 5.4 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) Baculo_PEP_C PF04513.12 CBK20208.2 - 3.5 7.7 5.7 27 4.8 0.9 2.4 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus V_ATPase_I PF01496.19 CBK20208.2 - 3.7 5.3 7.4 5.4 4.8 7.4 1.5 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family SOGA PF11365.8 CBK20208.2 - 9.1 7.5 9.7 1.3 10.2 0.3 3.1 2 1 1 3 3 3 0 Protein SOGA Histone_H2A_C PF16211.5 CBK20209.2 - 9.7e-16 57.2 0.0 1.5e-15 56.6 0.0 1.3 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 CBK20209.2 - 6.4e-13 49.2 0.0 9.6e-13 48.6 0.0 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 CBK20209.2 - 9.6e-06 25.8 0.0 1.3e-05 25.4 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 CBK20210.2 - 9.4e-18 64.8 0.1 1.1e-17 64.6 0.1 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 CBK20210.2 - 0.051 13.9 0.0 0.092 13.0 0.0 1.4 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 CBK20210.2 - 0.13 12.7 0.0 0.25 11.8 0.0 1.5 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A Proteasome PF00227.26 CBK20211.2 - 6.4e-17 61.7 0.0 6.9e-17 61.6 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Lys PF00062.20 CBK20211.2 - 0.048 13.9 0.0 0.059 13.6 0.0 1.1 1 0 0 1 1 1 0 C-type lysozyme/alpha-lactalbumin family SF1-HH PF16275.5 CBK20212.2 - 2.8e-23 82.4 1.7 7.7e-23 81.0 1.7 1.8 1 1 0 1 1 1 1 Splicing factor 1 helix-hairpin domain KH_1 PF00013.29 CBK20212.2 - 3.1e-10 39.7 1.5 6.9e-10 38.6 1.4 1.7 1 1 0 1 1 1 1 KH domain HrpB7 PF09486.10 CBK20212.2 - 0.06 13.7 1.8 0.52 10.7 0.2 2.3 2 0 0 2 2 2 0 Bacterial type III secretion protein (HrpB7) zf-C2H2_10 PF16588.5 CBK20212.2 - 1.2 9.0 3.7 0.51 10.1 0.8 1.9 2 0 0 2 2 2 0 C2H2 zinc-finger IF-2B PF01008.17 CBK20213.2 - 1.4e-43 149.1 0.2 1.7e-43 148.9 0.2 1.1 1 0 0 1 1 1 1 Initiation factor 2 subunit family PRKCSH-like PF12999.7 CBK20215.2 - 3.3e-20 72.6 19.4 3.6e-20 72.5 19.4 1.0 1 0 0 1 1 1 1 Glucosidase II beta subunit-like Sod_Fe_C PF02777.18 CBK20217.2 - 1.7e-39 134.1 0.3 1.7e-39 134.1 0.3 1.7 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 CBK20217.2 - 2.5e-19 69.5 4.8 1.2e-18 67.3 4.8 2.0 1 1 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain DUF3418 PF11898.8 CBK20217.2 - 0.16 10.6 0.0 0.18 10.4 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3418) Aminotran_5 PF00266.19 CBK20219.2 - 5.6e-35 121.0 0.1 9.8e-35 120.2 0.1 1.3 1 1 0 1 1 1 1 Aminotransferase class-V DENN PF02141.21 CBK20220.2 - 2.1e-18 66.9 8.2 3.7e-18 66.1 8.2 1.4 1 1 0 1 1 1 1 DENN (AEX-3) domain Peptidase_M41 PF01434.18 CBK20221.2 - 6e-57 192.6 0.3 9.5e-57 191.9 0.3 1.3 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 CBK20221.2 - 9.5e-44 149.0 0.0 2e-43 148.0 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CBK20221.2 - 1.1e-13 50.7 0.0 3.9e-13 49.0 0.0 2.0 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 CBK20221.2 - 9.4e-05 22.4 0.0 0.0004 20.4 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 CBK20221.2 - 0.00097 19.6 0.0 0.048 14.0 0.1 2.4 1 1 1 2 2 2 1 AAA ATPase domain AAA_2 PF07724.14 CBK20221.2 - 0.001 19.2 0.1 0.0041 17.2 0.0 2.1 2 0 0 2 2 1 1 AAA domain (Cdc48 subfamily) TIP49 PF06068.13 CBK20221.2 - 0.001 18.3 0.4 0.0059 15.9 0.1 2.1 1 1 1 2 2 2 1 TIP49 P-loop domain RuvB_N PF05496.12 CBK20221.2 - 0.004 16.9 0.0 0.011 15.5 0.0 1.7 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 CBK20221.2 - 0.0082 16.4 0.1 0.17 12.1 0.1 2.5 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.6 CBK20221.2 - 0.013 15.5 0.0 0.037 14.1 0.0 1.8 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 CBK20221.2 - 0.018 14.4 0.0 0.046 13.1 0.0 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_17 PF13207.6 CBK20221.2 - 0.037 14.4 0.3 0.18 12.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain PhoH PF02562.16 CBK20221.2 - 0.058 12.8 0.0 0.19 11.2 0.0 1.8 1 0 0 1 1 1 0 PhoH-like protein ATPase PF06745.13 CBK20221.2 - 0.061 12.7 0.7 0.82 9.0 0.0 2.3 2 0 0 2 2 2 0 KaiC IstB_IS21 PF01695.17 CBK20221.2 - 0.088 12.5 0.0 0.18 11.5 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_24 PF13479.6 CBK20221.2 - 0.1 12.3 0.5 1.2 8.8 0.1 2.7 2 1 1 3 3 3 0 AAA domain AAA_11 PF13086.6 CBK20221.2 - 0.1 12.3 0.0 0.2 11.4 0.0 1.6 1 1 0 1 1 1 0 AAA domain VAPB_antitox PF02697.14 CBK20221.2 - 5.6 7.8 6.0 11 6.9 0.4 3.5 3 1 1 4 4 4 0 Putative antitoxin UNC-93 PF05978.16 CBK20222.2 - 6.3e-21 74.7 12.0 6.3e-21 74.7 12.0 2.4 2 1 0 2 2 2 1 Ion channel regulatory protein UNC-93 MFS_1 PF07690.16 CBK20222.2 - 2.9e-11 42.9 33.3 3.9e-11 42.5 33.3 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily UFD1 PF03152.14 CBK20223.2 - 4.6e-48 162.9 0.3 5.8e-48 162.6 0.3 1.0 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 U1snRNP70_N PF12220.8 CBK20224.2 - 0.52 11.0 5.0 10 6.8 0.3 2.6 2 1 0 2 2 2 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal ENT PF03735.14 CBK20224.2 - 0.86 9.7 6.3 1.8 8.7 0.7 2.7 2 0 0 2 2 2 0 ENT domain DUF4140 PF13600.6 CBK20224.2 - 3.5 8.1 8.3 3.3 8.2 0.1 2.8 3 0 0 3 3 3 0 N-terminal domain of unknown function (DUF4140) Spc24 PF08286.11 CBK20224.2 - 4.4 7.6 15.6 1.8e+02 2.4 15.6 2.6 1 1 0 1 1 1 0 Spc24 subunit of Ndc80 DUF948 PF06103.11 CBK20224.2 - 6.2 7.2 6.6 5.1 7.4 1.9 2.7 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) KOG2701 PF09762.9 CBK20225.2 - 2.2e-24 86.7 0.0 2.5e-24 86.5 0.0 1.1 1 0 0 1 1 1 1 Coiled-coil domain-containing protein (DUF2037) Ndc80_HEC PF03801.13 CBK20225.2 - 0.13 11.9 0.0 0.2 11.3 0.0 1.4 1 0 0 1 1 1 0 HEC/Ndc80p family FYVE PF01363.21 CBK20226.2 - 8e-16 57.9 6.1 8e-16 57.9 6.1 2.3 2 1 0 2 2 2 2 FYVE zinc finger NOA36 PF06524.12 CBK20226.2 - 8.7 5.6 12.4 1.4 8.1 3.9 2.1 2 0 0 2 2 2 0 NOA36 protein Thymidylat_synt PF00303.19 CBK20227.2 - 2.6e-110 367.8 0.0 3.6e-110 367.3 0.0 1.2 1 0 0 1 1 1 1 Thymidylate synthase DHFR_1 PF00186.19 CBK20227.2 - 7.9e-38 129.7 0.1 1.2e-37 129.1 0.1 1.2 1 0 0 1 1 1 1 Dihydrofolate reductase 40S_S4_C PF16121.5 CBK20227.2 - 0.071 12.8 0.0 0.21 11.3 0.0 1.7 1 0 0 1 1 1 0 40S ribosomal protein S4 C-terminus Intron_maturas2 PF01348.21 CBK20227.2 - 0.11 12.5 0.0 0.37 10.7 0.0 1.9 2 0 0 2 2 2 0 Type II intron maturase DUF2012 PF09430.10 CBK20229.2 - 0.00044 20.4 0.0 0.0013 18.8 0.0 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF2012) Peptidase_M99_C PF17129.4 CBK20229.2 - 0.078 13.2 0.8 0.32 11.2 0.1 2.3 2 0 0 2 2 2 0 C-terminal domain of metallo-carboxypeptidase DnaJ_CXXCXGXG PF00684.19 CBK20230.2 - 4.4e-05 23.8 24.7 0.00033 21.0 24.8 2.5 1 1 0 1 1 1 1 DnaJ central domain DUF5351 PF17302.2 CBK20230.2 - 4.6 7.5 27.2 1.6 9.0 2.9 4.7 4 0 0 4 4 4 0 Family of unknown function (DUF5351) Pkinase PF00069.25 CBK20232.2 - 2.8e-56 190.8 0.0 3.5e-56 190.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBK20232.2 - 5.4e-22 78.3 0.0 1.9e-21 76.5 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 CBK20232.2 - 0.021 13.8 0.0 0.027 13.4 0.0 1.1 1 0 0 1 1 1 0 Haspin like kinase domain Kinase-like PF14531.6 CBK20232.2 - 0.15 11.4 0.0 0.26 10.5 0.0 1.4 1 1 0 1 1 1 0 Kinase-like DMA PF03474.14 CBK20232.2 - 0.19 11.4 0.1 0.45 10.1 0.1 1.6 1 0 0 1 1 1 0 DMRTA motif DEAD PF00270.29 CBK20233.2 - 1.6e-40 138.8 0.1 4.3e-40 137.3 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CBK20233.2 - 3e-29 101.6 0.0 6.8e-29 100.4 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 CBK20233.2 - 8.4e-06 25.9 0.0 2.1e-05 24.6 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Metallophos PF00149.28 CBK20234.2 - 6.6e-25 88.8 0.1 1.3e-24 87.9 0.1 1.5 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase LRR_8 PF13855.6 CBK20235.2 - 0.098 12.4 19.9 0.12 12.2 1.0 7.9 8 3 0 8 8 8 0 Leucine rich repeat F-box PF00646.33 CBK20235.2 - 0.15 12.0 3.6 0.41 10.6 0.3 2.9 2 0 0 2 2 2 0 F-box domain LRR_4 PF12799.7 CBK20235.2 - 0.45 11.0 36.2 0.49 10.9 0.6 8.4 7 2 3 10 10 10 0 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 CBK20235.2 - 0.68 10.1 28.7 10 6.4 0.1 10.7 11 0 0 11 11 11 0 Leucine Rich repeat MFS_1 PF07690.16 CBK20236.2 - 0.012 14.6 0.0 0.012 14.6 0.0 1.0 1 0 0 1 1 1 0 Major Facilitator Superfamily cwf21 PF08312.12 CBK20237.2 - 2.9e-07 30.5 8.2 8.2e-07 29.1 8.2 1.8 1 0 0 1 1 1 1 cwf21 domain XG_FTase PF03254.13 CBK20237.2 - 0.11 11.1 0.0 0.11 11.1 0.0 2.9 3 0 0 3 3 3 0 Xyloglucan fucosyltransferase GREB1 PF15782.5 CBK20237.2 - 3.3 4.7 30.4 4.3 4.3 30.4 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer EMP24_GP25L PF01105.24 CBK20238.2 - 2.6e-21 76.4 1.8 3e-21 76.2 1.8 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD AOX PF01786.17 CBK20239.2 - 8.8e-61 205.2 0.0 1.2e-60 204.8 0.0 1.1 1 0 0 1 1 1 1 Alternative oxidase Peptidase_M16 PF00675.20 CBK20240.2 - 8.6e-44 149.1 0.0 1.9e-43 148.0 0.0 1.6 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 CBK20240.2 - 4.6e-28 98.5 0.0 9.3e-28 97.5 0.0 1.5 1 0 0 1 1 1 1 Peptidase M16 inactive domain Peptidase_M44 PF03410.13 CBK20240.2 - 0.12 11.0 0.0 0.74 8.3 0.0 2.0 1 1 0 1 1 1 0 Metallopeptidase from vaccinia pox Gtr1_RagA PF04670.12 CBK20240.2 - 0.19 11.0 0.0 0.33 10.3 0.0 1.3 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region RRM_1 PF00076.22 CBK20241.2 - 8.6e-18 63.9 0.0 1e-17 63.7 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 CBK20241.2 - 7.5e-07 28.8 0.0 9.8e-07 28.4 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 CBK20241.2 - 0.16 12.0 0.8 0.74 9.9 0.1 2.0 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif DUF4523 PF15023.6 CBK20241.2 - 0.2 11.5 0.0 0.24 11.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4523) NifU_N PF01592.16 CBK20242.2 - 1.1e-52 177.5 0.1 1.3e-52 177.3 0.1 1.0 1 0 0 1 1 1 1 NifU-like N terminal domain DUF4061 PF13270.6 CBK20243.2 - 4.2e-07 30.2 0.6 5.7e-07 29.8 0.6 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4061) IF4E PF01652.18 CBK20244.2 - 7.9e-36 123.2 0.0 1e-35 122.9 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E 14-3-3 PF00244.20 CBK20245.2 - 2.9e-71 239.5 7.5 3.3e-71 239.3 7.5 1.0 1 0 0 1 1 1 1 14-3-3 protein EspA PF03433.13 CBK20245.2 - 0.03 14.2 0.1 0.081 12.8 0.0 1.4 1 1 0 1 1 1 0 EspA-like secreted protein FlaF PF07309.11 CBK20245.2 - 0.043 13.8 0.2 0.14 12.2 0.2 1.8 1 0 0 1 1 1 0 Flagellar protein FlaF Virulence_fact PF13769.6 CBK20245.2 - 0.053 13.8 1.0 22 5.4 0.0 3.1 3 0 0 3 3 3 0 Virulence factor TPR_8 PF13181.6 CBK20245.2 - 0.39 11.1 8.8 17 5.9 0.0 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.17 CBK20245.2 - 2.5 8.4 4.5 4.1 7.8 0.2 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat ERCC4 PF02732.15 CBK20247.2 - 1e-18 68.1 0.0 1.7e-18 67.3 0.0 1.4 1 0 0 1 1 1 1 ERCC4 domain Ribosomal_L11_N PF03946.14 CBK20248.2 - 7.4e-18 64.2 0.5 1.2e-17 63.5 0.5 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.19 CBK20248.2 - 2.9e-17 62.9 0.1 4.6e-17 62.3 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain GHMP_kinases_C PF08544.13 CBK20249.2 - 5.6e-09 36.2 0.0 1.4e-08 34.9 0.0 1.7 1 0 0 1 1 1 1 GHMP kinases C terminal GHMP_kinases_N PF00288.26 CBK20249.2 - 1.5e-07 31.5 0.0 2.6e-07 30.8 0.0 1.4 1 0 0 1 1 1 1 GHMP kinases N terminal domain Pkinase PF00069.25 CBK20252.2 - 3.8e-17 62.5 0.0 4.7e-17 62.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBK20252.2 - 1.7e-10 40.7 0.0 1.7e-10 40.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase PEP-utilizers PF00391.23 CBK20253.2 - 2.3e-18 65.7 1.1 3.2e-18 65.2 0.4 1.6 2 0 0 2 2 2 1 PEP-utilising enzyme, mobile domain Spermine_synth PF01564.17 CBK20254.2 - 7.4e-08 32.0 0.0 1.2e-07 31.4 0.0 1.3 1 0 0 1 1 1 1 Spermine/spermidine synthase domain Methyltransf_25 PF13649.6 CBK20254.2 - 0.00015 22.4 0.0 0.00034 21.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CBK20254.2 - 0.0061 17.3 0.0 0.012 16.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 CBK20254.2 - 0.0064 16.0 0.0 0.01 15.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_24 PF13578.6 CBK20254.2 - 0.014 16.4 0.0 0.035 15.1 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase domain RrnaAD PF00398.20 CBK20254.2 - 0.031 13.4 0.1 0.12 11.4 0.0 1.9 1 1 1 2 2 2 0 Ribosomal RNA adenine dimethylase CHASE2 PF05226.11 CBK20254.2 - 0.034 13.9 0.0 0.054 13.2 0.0 1.4 1 0 0 1 1 1 0 CHASE2 domain TRAM_2 PF18693.1 CBK20254.2 - 0.06 13.5 1.5 0.32 11.2 1.5 2.2 1 1 0 1 1 1 0 TRAM domain Methyltransf_3 PF01596.17 CBK20254.2 - 0.21 10.7 1.7 0.25 10.5 0.9 1.4 1 1 0 1 1 1 0 O-methyltransferase RRM_1 PF00076.22 CBK20255.2 - 2.2e-13 49.8 0.0 3.5e-13 49.1 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 CBK20255.2 - 0.0087 16.1 3.7 0.015 15.3 3.7 1.4 1 0 0 1 1 1 1 RNA binding motif RRM_5 PF13893.6 CBK20255.2 - 0.044 13.4 0.1 0.075 12.6 0.1 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Trypan_PARP PF05887.11 CBK20255.2 - 0.27 11.2 1.8 0.48 10.4 1.8 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) ETRAMP PF09716.10 CBK20256.2 - 0.2 11.7 0.1 5.7 7.1 0.0 2.5 3 0 0 3 3 3 0 Malarial early transcribed membrane protein (ETRAMP) DUF3273 PF11677.8 CBK20256.2 - 0.28 10.5 6.4 0.39 10.0 6.4 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3273) PA28_beta PF02252.18 CBK20257.2 - 9.2e-43 145.4 0.2 1.1e-42 145.2 0.2 1.0 1 0 0 1 1 1 1 Proteasome activator pa28 beta subunit Carboxyl_trans PF01039.22 CBK20258.2 - 4.9e-190 632.4 0.1 5.8e-190 632.1 0.1 1.0 1 0 0 1 1 1 1 Carboxyl transferase domain MdcE PF06833.11 CBK20258.2 - 0.0093 15.5 0.0 0.03 13.8 0.0 1.8 3 0 0 3 3 3 1 Malonate decarboxylase gamma subunit (MdcE) Glyco_transf_49 PF13896.6 CBK20259.2 - 1.9e-29 103.1 0.5 2e-24 86.6 0.3 2.1 1 1 1 2 2 2 2 Glycosyl-transferase for dystroglycan Shisa PF13908.6 CBK20260.2 - 0.00018 21.8 4.4 0.00018 21.8 4.4 2.0 2 1 0 2 2 2 1 Wnt and FGF inhibitory regulator Glycophorin_A PF01102.18 CBK20260.2 - 0.0057 16.9 1.1 0.012 15.9 1.1 1.5 1 0 0 1 1 1 1 Glycophorin A TMEM154 PF15102.6 CBK20260.2 - 0.015 15.2 0.4 0.029 14.3 0.4 1.5 1 0 0 1 1 1 0 TMEM154 protein family LRRC37AB_C PF14914.6 CBK20260.2 - 0.02 14.8 0.9 0.041 13.8 0.9 1.5 1 0 0 1 1 1 0 LRRC37A/B like protein 1 C-terminal domain EphA2_TM PF14575.6 CBK20260.2 - 0.037 14.9 0.1 0.087 13.7 0.1 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain ODV-E18 PF10717.9 CBK20260.2 - 0.084 12.8 2.1 0.17 11.8 2.1 1.5 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 SP_C-Propep PF08999.10 CBK20260.2 - 0.09 12.6 1.6 0.17 11.7 1.6 1.4 1 0 0 1 1 1 0 Surfactant protein C, N terminal propeptide DUF929 PF06053.11 CBK20260.2 - 0.12 11.6 1.7 0.2 10.9 1.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF929) Peptidase_C4 PF00863.19 CBK20260.2 - 0.16 11.3 0.1 0.22 10.8 0.1 1.1 1 0 0 1 1 1 0 Peptidase family C4 DUF5385 PF17359.2 CBK20260.2 - 0.59 9.7 1.1 0.81 9.2 1.1 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5385) Glyco_hydro_63N PF16923.5 CBK20261.2 - 9.5e-19 68.4 0.0 1e-18 68.2 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 63 N-terminal domain Glyco_hydro_63 PF03200.16 CBK20262.2 - 8e-136 453.7 2.1 2.1e-135 452.3 2.1 1.5 1 1 0 1 1 1 1 Glycosyl hydrolase family 63 C-terminal domain zf-C3HC4_3 PF13920.6 CBK20263.2 - 2.1e-09 37.1 11.1 2.9e-09 36.6 11.1 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CBK20263.2 - 4e-09 36.7 11.3 5.5e-09 36.2 11.3 1.2 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 CBK20263.2 - 8.2e-09 35.3 11.5 1.2e-08 34.8 11.5 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 CBK20263.2 - 1.2e-08 34.8 3.4 1.2e-08 34.8 3.4 2.1 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 CBK20263.2 - 2.3e-08 33.7 11.5 3.8e-08 33.0 11.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-P11 PF03854.14 CBK20263.2 - 4.5e-06 26.2 8.2 7.4e-06 25.5 4.8 2.2 2 0 0 2 2 2 1 P-11 zinc finger zf-C3HC4 PF00097.25 CBK20263.2 - 2e-05 24.4 12.7 3.4e-05 23.6 12.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.6 CBK20263.2 - 0.00024 20.9 3.8 0.00036 20.3 3.8 1.3 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-RING_4 PF14570.6 CBK20263.2 - 0.00031 20.5 8.6 0.00047 19.9 8.6 1.2 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain Prok-RING_4 PF14447.6 CBK20263.2 - 0.00043 20.1 12.6 0.0017 18.2 12.7 1.8 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-rbx1 PF12678.7 CBK20263.2 - 0.00044 20.5 11.7 0.0015 18.8 11.7 1.8 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_4 PF15227.6 CBK20263.2 - 0.0095 16.1 12.3 0.036 14.2 12.3 2.0 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-UDP PF14569.6 CBK20263.2 - 0.02 15.0 5.8 0.029 14.5 5.8 1.3 1 0 0 1 1 1 0 Zinc-binding RING-finger FYVE PF01363.21 CBK20263.2 - 0.13 12.4 11.5 0.65 10.2 11.5 2.0 1 1 0 1 1 1 0 FYVE zinc finger PHD PF00628.29 CBK20263.2 - 0.14 12.1 9.3 0.24 11.3 9.3 1.4 1 1 0 1 1 1 0 PHD-finger zf-RING_11 PF17123.5 CBK20263.2 - 0.16 11.8 10.9 0.87 9.4 8.7 2.4 2 0 0 2 2 2 0 RING-like zinc finger IBR PF01485.21 CBK20263.2 - 0.38 11.0 11.2 0.069 13.4 5.3 2.1 1 1 1 2 2 2 0 IBR domain, a half RING-finger domain FYVE_2 PF02318.16 CBK20263.2 - 0.71 10.1 13.1 0.25 11.6 7.7 2.0 1 1 1 2 2 2 0 FYVE-type zinc finger DZR PF12773.7 CBK20263.2 - 0.96 9.5 9.3 10 6.2 1.9 2.2 1 1 1 2 2 2 0 Double zinc ribbon OrfB_Zn_ribbon PF07282.11 CBK20263.2 - 1 9.3 6.7 16 5.5 0.1 2.2 1 1 1 2 2 2 0 Putative transposase DNA-binding domain Zn-ribbon_8 PF09723.10 CBK20263.2 - 1.9 8.7 8.7 1.1 9.4 5.5 2.1 1 1 1 2 2 2 0 Zinc ribbon domain zf-B_box PF00643.24 CBK20263.2 - 2.1 8.6 11.8 0.8 9.9 6.4 2.3 2 1 0 2 2 2 0 B-box zinc finger Zn_Tnp_IS91 PF14319.6 CBK20263.2 - 5.4 7.1 11.2 44 4.2 11.2 2.1 1 1 0 1 1 1 0 Transposase zinc-binding domain zf-ANAPC11 PF12861.7 CBK20263.2 - 5.9 7.0 9.9 24 5.1 9.9 1.9 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger RecR PF02132.15 CBK20263.2 - 7.1 6.3 13.4 0.24 11.0 1.9 3.0 2 1 1 3 3 3 0 RecR protein LRR_6 PF13516.6 CBK20264.2 - 1.8e-07 30.7 0.0 1.2e-05 24.9 0.0 3.1 3 0 0 3 3 3 1 Leucine Rich repeat LRR_1 PF00560.33 CBK20264.2 - 0.0086 16.5 0.3 0.57 10.9 0.0 3.4 4 0 0 4 4 4 1 Leucine Rich Repeat LRR_9 PF14580.6 CBK20264.2 - 0.06 12.8 2.1 0.41 10.1 0.4 2.0 1 1 1 2 2 2 0 Leucine-rich repeat SWIM PF04434.17 CBK20264.2 - 5.6 6.7 5.0 0.88 9.3 0.4 2.0 2 0 0 2 2 2 0 SWIM zinc finger AAA PF00004.29 CBK20265.2 - 2.9e-29 102.2 0.0 1.4e-27 96.8 0.0 2.1 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 CBK20265.2 - 8.8e-09 35.8 0.1 5.9e-08 33.1 0.1 2.1 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 CBK20265.2 - 3.6e-06 27.6 0.0 5.9e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 CBK20265.2 - 8.6e-06 26.2 0.1 3.9e-05 24.1 0.1 2.2 1 1 0 1 1 1 1 AAA ATPase domain DUF815 PF05673.13 CBK20265.2 - 4.6e-05 22.7 0.0 0.0016 17.7 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_14 PF13173.6 CBK20265.2 - 4.8e-05 23.4 0.0 7.4e-05 22.8 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.14 CBK20265.2 - 6.5e-05 22.9 0.0 0.0012 18.9 0.0 2.1 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) NACHT PF05729.12 CBK20265.2 - 0.00012 22.0 0.1 0.00055 19.9 0.1 2.0 1 1 0 1 1 1 1 NACHT domain RNA_helicase PF00910.22 CBK20265.2 - 0.00069 20.0 0.0 0.0015 18.9 0.0 1.6 1 0 0 1 1 1 1 RNA helicase AAA_33 PF13671.6 CBK20265.2 - 0.00094 19.4 0.0 0.0018 18.4 0.0 1.6 2 0 0 2 2 1 1 AAA domain Cytidylate_kin PF02224.18 CBK20265.2 - 0.00096 18.9 0.0 0.0038 17.0 0.0 1.8 1 1 0 2 2 2 1 Cytidylate kinase AAA_28 PF13521.6 CBK20265.2 - 0.0011 19.2 0.0 0.0019 18.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain Rad17 PF03215.15 CBK20265.2 - 0.0014 18.6 1.2 0.0057 16.6 0.1 2.3 2 1 1 3 3 3 1 Rad17 P-loop domain TsaE PF02367.17 CBK20265.2 - 0.0018 18.3 0.0 0.003 17.6 0.0 1.3 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_30 PF13604.6 CBK20265.2 - 0.0018 18.0 0.0 0.003 17.3 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_11 PF13086.6 CBK20265.2 - 0.0026 17.6 0.0 0.0042 16.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 CBK20265.2 - 0.0026 17.5 0.0 0.0051 16.6 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein RuvB_N PF05496.12 CBK20265.2 - 0.0027 17.5 0.1 0.01 15.6 0.0 1.8 1 1 1 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_7 PF12775.7 CBK20265.2 - 0.0028 17.2 0.0 0.0045 16.5 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region Mg_chelatase PF01078.21 CBK20265.2 - 0.0029 17.0 0.0 0.013 14.9 0.0 1.8 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI TIP49 PF06068.13 CBK20265.2 - 0.0093 15.2 0.0 0.013 14.8 0.0 1.2 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_24 PF13479.6 CBK20265.2 - 0.0097 15.6 0.0 0.03 14.0 0.0 1.9 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.6 CBK20265.2 - 0.0097 16.2 0.1 0.043 14.1 0.1 2.0 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.6 CBK20265.2 - 0.019 15.4 0.0 0.03 14.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 CBK20265.2 - 0.021 15.3 0.0 0.039 14.5 0.0 1.4 1 0 0 1 1 1 0 ABC transporter AAA_2 PF07724.14 CBK20265.2 - 0.022 14.9 0.0 0.059 13.5 0.0 1.7 1 1 0 1 1 1 0 AAA domain (Cdc48 subfamily) ATPase_2 PF01637.18 CBK20265.2 - 0.025 14.5 0.0 0.48 10.3 0.0 2.1 1 1 1 2 2 2 0 ATPase domain predominantly from Archaea Viral_helicase1 PF01443.18 CBK20265.2 - 0.03 14.1 0.0 0.047 13.4 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_25 PF13481.6 CBK20265.2 - 0.033 13.8 0.0 0.066 12.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 CBK20265.2 - 0.037 13.7 0.0 0.08 12.6 0.0 1.5 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA_13 PF13166.6 CBK20265.2 - 0.037 12.7 0.0 0.054 12.1 0.0 1.2 1 0 0 1 1 1 0 AAA domain KAP_NTPase PF07693.14 CBK20265.2 - 0.042 13.1 0.1 2 7.6 0.0 2.1 1 1 1 2 2 2 0 KAP family P-loop domain AAA_3 PF07726.11 CBK20265.2 - 0.052 13.4 0.0 0.39 10.6 0.0 2.1 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) DnaB_C PF03796.15 CBK20265.2 - 0.057 12.7 0.0 0.2 11.0 0.0 1.8 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain NTPase_1 PF03266.15 CBK20265.2 - 0.057 13.3 0.0 0.17 11.8 0.0 1.7 2 0 0 2 2 2 0 NTPase PduV-EutP PF10662.9 CBK20265.2 - 0.08 12.7 0.0 0.19 11.5 0.0 1.6 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_6 PF12774.7 CBK20265.2 - 0.11 11.5 0.1 0.33 9.9 0.0 1.8 2 1 0 2 2 2 0 Hydrolytic ATP binding site of dynein motor region ATPase PF06745.13 CBK20265.2 - 0.12 11.7 0.1 1 8.7 0.0 2.0 1 1 1 2 2 2 0 KaiC PhoH PF02562.16 CBK20265.2 - 0.15 11.5 0.0 0.35 10.3 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein NB-ARC PF00931.22 CBK20265.2 - 0.16 11.1 0.0 0.24 10.6 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain DUF2075 PF09848.9 CBK20265.2 - 0.17 11.1 0.0 0.23 10.7 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Pinin_SDK_memA PF04696.13 CBK20266.2 - 3e-15 56.4 3.0 3e-15 56.4 3.0 6.2 1 1 1 3 3 3 1 pinin/SDK/memA/ protein conserved region RSB_motif PF16294.5 CBK20266.2 - 0.00088 19.5 0.6 0.00088 19.5 0.6 6.6 2 2 1 3 3 3 1 RNSP1-SAP18 binding (RSB) motif Ureide_permease PF07168.11 CBK20267.2 - 0.15 10.8 2.3 0.27 10.0 2.3 1.3 1 0 0 1 1 1 0 Ureide permease DUF945 PF06097.11 CBK20267.2 - 0.3 10.2 0.2 0.38 9.8 0.2 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF945) ABC_membrane PF00664.23 CBK20268.2 - 3.9e-59 200.6 36.1 2.3e-34 119.3 13.1 2.4 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 CBK20268.2 - 1.1e-52 178.2 0.5 1.9e-29 102.9 0.0 2.8 3 0 0 3 3 2 2 ABC transporter SMC_N PF02463.19 CBK20268.2 - 5e-09 35.9 13.7 0.0081 15.6 0.5 4.7 4 1 1 5 5 5 3 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 CBK20268.2 - 2.9e-07 30.6 0.2 0.0012 18.7 0.0 3.1 3 0 0 3 3 3 2 RsgA GTPase MMR_HSR1 PF01926.23 CBK20268.2 - 7.5e-07 29.2 1.4 0.011 15.8 0.0 3.2 3 0 0 3 3 3 2 50S ribosome-binding GTPase Dynamin_N PF00350.23 CBK20268.2 - 5.7e-05 23.2 4.0 0.012 15.7 0.0 3.4 3 0 0 3 3 3 1 Dynamin family AAA_16 PF13191.6 CBK20268.2 - 0.00019 21.9 0.3 0.74 10.2 0.0 3.1 3 0 0 3 3 3 2 AAA ATPase domain AAA_29 PF13555.6 CBK20268.2 - 0.00036 20.2 0.3 0.34 10.7 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_21 PF13304.6 CBK20268.2 - 0.0031 17.4 0.4 6.6 6.5 0.0 3.6 2 1 1 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 CBK20268.2 - 0.0034 17.9 15.5 0.01 16.4 0.0 3.8 4 0 0 4 4 3 1 AAA domain AAA_24 PF13479.6 CBK20268.2 - 0.0051 16.6 0.0 0.042 13.6 0.0 2.5 2 1 0 2 2 2 1 AAA domain DUF815 PF05673.13 CBK20268.2 - 0.0071 15.5 0.1 1.6 7.9 0.1 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_22 PF13401.6 CBK20268.2 - 0.0081 16.4 0.0 2.4 8.4 0.0 2.9 2 1 0 2 2 2 1 AAA domain Sec62 PF03839.16 CBK20268.2 - 0.012 15.1 0.2 0.034 13.7 0.2 1.7 1 0 0 1 1 1 0 Translocation protein Sec62 Zeta_toxin PF06414.12 CBK20268.2 - 0.023 14.0 0.0 4.2 6.6 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin AAA PF00004.29 CBK20268.2 - 0.04 14.3 0.3 19 5.7 0.0 3.2 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) DUF87 PF01935.17 CBK20268.2 - 0.056 13.5 3.5 0.57 10.2 0.1 2.7 3 0 0 3 3 2 0 Helicase HerA, central domain AIG1 PF04548.16 CBK20268.2 - 0.06 12.7 0.4 2.5 7.4 0.0 2.6 2 0 0 2 2 2 0 AIG1 family Roc PF08477.13 CBK20268.2 - 0.13 12.5 0.2 17 5.6 0.1 3.1 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_15 PF13175.6 CBK20268.2 - 0.2 11.3 5.1 0.37 10.5 0.1 2.9 3 0 0 3 3 3 0 AAA ATPase domain Abhydrolase_9_N PF15420.6 CBK20268.2 - 4.8 7.1 9.4 1.9 8.5 0.9 3.2 3 1 0 3 3 3 0 Alpha/beta-hydrolase family N-terminus SRP54 PF00448.22 CBK20270.2 - 4.8e-53 179.7 0.0 8.9e-53 178.8 0.0 1.5 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SRP-alpha_N PF04086.13 CBK20270.2 - 5.9e-42 144.6 8.2 9.1e-42 144.0 8.2 1.2 1 0 0 1 1 1 1 Signal recognition particle, alpha subunit, N-terminal SRP54_N PF02881.19 CBK20270.2 - 3.8e-09 36.6 0.3 1.7e-08 34.6 0.3 2.2 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain MeaB PF03308.16 CBK20270.2 - 2.4e-06 26.7 0.0 9.7e-06 24.7 0.0 1.9 1 1 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB CbiA PF01656.23 CBK20270.2 - 1.7e-05 24.9 3.7 0.0062 16.6 0.0 3.1 3 1 0 3 3 3 2 CobQ/CobB/MinD/ParA nucleotide binding domain NTPase_1 PF03266.15 CBK20270.2 - 0.00011 22.1 0.0 0.12 12.2 0.0 2.8 2 1 0 2 2 2 2 NTPase AAA_16 PF13191.6 CBK20270.2 - 0.00048 20.6 0.0 0.0013 19.1 0.0 1.8 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 CBK20270.2 - 0.00049 20.4 0.0 0.0013 19.1 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 CBK20270.2 - 0.0066 16.2 0.0 0.012 15.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain DAP3 PF10236.9 CBK20270.2 - 0.0084 15.3 0.9 0.012 14.9 0.1 1.6 2 0 0 2 2 2 1 Mitochondrial ribosomal death-associated protein 3 CoA_binding_2 PF13380.6 CBK20270.2 - 0.026 15.0 0.0 5.2 7.6 0.0 2.5 2 0 0 2 2 2 0 CoA binding domain AAA_33 PF13671.6 CBK20270.2 - 0.062 13.5 0.0 0.16 12.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_31 PF13614.6 CBK20270.2 - 0.074 13.0 0.0 0.31 10.9 0.0 2.1 1 1 0 1 1 1 0 AAA domain GAGA_bind PF06217.12 CBK20270.2 - 0.25 11.6 4.3 0.37 11.0 4.3 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family FKBP_N PF01346.18 CBK20270.2 - 0.3 12.1 3.2 21 6.2 3.4 2.7 2 1 1 3 3 2 0 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase DUF4247 PF14042.6 CBK20270.2 - 0.37 11.5 4.2 0.79 10.4 4.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4247) SPATA3 PF15662.5 CBK20270.2 - 1.8 9.2 13.6 0.33 11.6 10.1 1.5 1 1 0 1 1 1 0 Spermatogenesis-associated protein 3 family DUF3807 PF12720.7 CBK20270.2 - 4.5 7.5 12.1 7.3 6.8 12.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) DnaJ PF00226.31 CBK20271.2 - 9.2e-29 99.4 6.0 9.2e-29 99.4 6.0 3.1 3 0 0 3 3 2 1 DnaJ domain TPR_2 PF07719.17 CBK20271.2 - 2.8e-19 67.6 11.2 7.6e-05 22.5 0.1 7.8 6 1 1 7 7 7 4 Tetratricopeptide repeat TPR_1 PF00515.28 CBK20271.2 - 7.5e-17 60.4 17.9 0.0076 16.0 0.2 7.4 6 1 1 7 7 7 5 Tetratricopeptide repeat TPR_8 PF13181.6 CBK20271.2 - 2e-14 52.5 14.0 0.00081 19.4 0.0 7.4 6 2 2 8 8 7 3 Tetratricopeptide repeat TPR_16 PF13432.6 CBK20271.2 - 4.2e-14 52.9 0.0 0.0018 18.9 0.0 4.4 4 0 0 4 4 3 3 Tetratricopeptide repeat TPR_14 PF13428.6 CBK20271.2 - 3.8e-12 45.9 0.1 0.037 14.8 0.0 5.5 5 1 1 6 6 6 2 Tetratricopeptide repeat ANAPC3 PF12895.7 CBK20271.2 - 3.4e-11 43.2 18.1 0.00036 20.7 0.1 5.1 3 2 2 5 5 5 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.6 CBK20271.2 - 8.9e-11 41.9 9.6 0.014 15.6 0.1 5.6 5 1 0 5 5 4 3 Tetratricopeptide repeat TPR_6 PF13174.6 CBK20271.2 - 2.2e-09 37.3 8.4 0.047 14.3 0.0 6.8 8 0 0 8 8 6 2 Tetratricopeptide repeat TPR_19 PF14559.6 CBK20271.2 - 1.1e-08 35.4 15.4 0.0065 16.9 0.0 5.6 6 1 0 6 6 4 3 Tetratricopeptide repeat TPR_7 PF13176.6 CBK20271.2 - 7.5e-07 28.7 8.5 0.013 15.4 0.1 5.7 5 1 0 5 5 5 1 Tetratricopeptide repeat TPR_10 PF13374.6 CBK20271.2 - 1.9e-05 24.3 8.0 0.0026 17.6 0.5 4.6 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_9 PF13371.6 CBK20271.2 - 3.3e-05 23.9 0.3 0.47 10.6 0.0 4.4 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_17 PF13431.6 CBK20271.2 - 7.4e-05 22.9 6.2 0.19 12.2 0.0 5.0 6 0 0 6 6 4 2 Tetratricopeptide repeat TPR_MalT PF17874.1 CBK20271.2 - 0.015 14.6 2.4 0.64 9.3 0.0 3.2 3 1 1 4 4 4 0 MalT-like TPR region TPR_20 PF14561.6 CBK20271.2 - 0.021 15.1 13.1 1.3 9.4 1.5 4.8 4 2 2 6 6 6 0 Tetratricopeptide repeat Wzy_C_2 PF11846.8 CBK20271.2 - 0.023 14.6 0.0 0.11 12.4 0.0 2.0 1 1 0 1 1 1 0 Virulence factor membrane-bound polymerase, C-terminal ANAPC5 PF12862.7 CBK20271.2 - 0.029 14.4 1.0 4.2 7.5 0.6 3.5 3 1 0 3 3 3 0 Anaphase-promoting complex subunit 5 FlbT PF07378.11 CBK20271.2 - 0.042 13.9 6.0 1 9.5 0.8 3.8 3 1 1 4 4 3 0 Flagellar protein FlbT Erf4 PF10256.9 CBK20271.2 - 0.054 13.6 0.2 1.7 8.8 0.0 3.0 3 0 0 3 3 3 0 Golgin subfamily A member 7/ERF4 family TPR_11 PF13414.6 CBK20271.2 - 0.22 11.2 10.6 8.2 6.2 0.1 5.7 5 1 1 6 6 6 0 TPR repeat Alkyl_sulf_dimr PF14863.6 CBK20271.2 - 0.24 11.8 6.4 1.4 9.4 1.7 3.5 3 2 0 3 3 3 0 Alkyl sulfatase dimerisation TPR_4 PF07721.14 CBK20271.2 - 0.27 12.0 1.7 2.6 8.9 0.0 3.0 3 0 0 3 3 2 0 Tetratricopeptide repeat ADP_ribosyl_GH PF03747.14 CBK20271.2 - 0.54 9.9 3.2 1.3 8.6 2.9 1.9 1 1 0 1 1 1 0 ADP-ribosylglycohydrolase TPR_3 PF07720.12 CBK20271.2 - 1.3 9.1 10.2 18 5.4 1.1 5.8 7 0 0 7 7 6 0 Tetratricopeptide repeat DUF4810 PF16068.5 CBK20271.2 - 2.6 8.7 0.0 2.6 8.7 0.0 3.9 4 2 1 5 5 4 0 Domain of unknown function (DUF4810) Thioredoxin_8 PF13905.6 CBK20271.2 - 4 7.8 6.7 2.8 8.4 1.2 2.8 2 0 0 2 2 2 0 Thioredoxin-like T3SS_needle_E PF08988.10 CBK20271.2 - 5.5 7.2 6.6 1.8 8.8 1.8 2.7 3 0 0 3 3 2 0 Type III secretion system, cytoplasmic E component of needle FAM131 PF15010.6 CBK20271.2 - 6.8 6.5 7.0 0.62 9.9 0.2 2.1 2 0 0 2 2 2 0 Putative cell signalling MTBP_N PF14918.6 CBK20271.2 - 9.4 5.6 11.0 5.5 6.4 0.3 3.4 3 1 0 3 3 3 0 MDM2-binding DUF1771 PF08590.10 CBK20272.2 - 7.9e-20 71.0 8.8 1.3e-19 70.3 8.8 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1771) Smr PF01713.21 CBK20272.2 - 4e-08 33.5 0.0 8.7e-08 32.4 0.0 1.5 1 0 0 1 1 1 1 Smr domain Methyltransf_24 PF13578.6 CBK20272.2 - 0.021 15.8 0.0 0.032 15.3 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain OmpH PF03938.14 CBK20272.2 - 0.068 13.5 3.9 0.11 12.9 3.9 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF4175 PF13779.6 CBK20272.2 - 0.57 8.0 3.7 0.77 7.6 3.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Paralemmin PF03285.15 CBK20272.2 - 4.4 6.8 13.8 0.078 12.6 5.3 2.0 2 0 0 2 2 2 0 Paralemmin Vps54_N PF10475.9 CBK20273.2 - 0.00019 20.8 0.3 0.0006 19.2 0.0 1.8 2 0 0 2 2 2 1 Vacuolar-sorting protein 54, of GARP complex WXG100 PF06013.12 CBK20273.2 - 2.8 8.2 5.2 13 6.1 0.9 2.2 2 0 0 2 2 2 0 Proteins of 100 residues with WXG Vps54 PF07928.12 CBK20274.2 - 7.7e-31 107.3 6.5 1.2e-30 106.7 1.6 2.3 2 0 0 2 2 2 1 Vps54-like protein DUF1485 PF07364.12 CBK20274.2 - 0.018 14.3 0.1 0.15 11.3 0.0 2.1 1 1 1 2 2 2 0 Metallopeptidase family M81 LRR_8 PF13855.6 CBK20275.2 - 0.0079 15.9 3.3 9.1 6.1 0.1 4.1 3 1 1 4 4 4 2 Leucine rich repeat Trypan_PARP PF05887.11 CBK20275.2 - 0.048 13.6 2.7 0.11 12.5 2.7 1.5 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) GBP PF02263.19 CBK20276.2 - 7.9e-37 126.9 0.0 1e-36 126.5 0.0 1.1 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain MFS_1 PF07690.16 CBK20277.2 - 6.6e-44 150.3 23.2 1.1e-31 110.1 13.9 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 CBK20277.2 - 4.8e-12 45.5 26.2 8.6e-12 44.6 26.1 1.5 1 1 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.13 CBK20277.2 - 5.2e-06 25.2 4.0 5.2e-06 25.2 4.0 1.6 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) AXH PF08517.12 CBK20277.2 - 2 9.0 5.4 25 5.4 0.1 3.2 4 0 0 4 4 4 0 Ataxin-1 and HBP1 module (AXH) NUC153 PF08159.12 CBK20278.2 - 7.7e-11 41.6 0.3 1.6e-10 40.6 0.3 1.6 1 0 0 1 1 1 1 NUC153 domain ANAPC4_WD40 PF12894.7 CBK20278.2 - 9.3e-06 25.9 0.0 0.012 15.8 0.0 2.6 1 1 1 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain Wyosine_form PF08608.12 CBK20279.2 - 7.8e-19 67.8 0.0 1.9e-18 66.5 0.0 1.7 1 0 0 1 1 1 1 Wyosine base formation Radical_SAM PF04055.21 CBK20279.2 - 1.3e-17 64.7 1.6 1.8e-17 64.2 0.1 2.1 2 1 0 2 2 2 1 Radical SAM superfamily DnaB_bind PF10410.9 CBK20279.2 - 0.047 13.9 0.0 0.18 12.0 0.0 2.0 2 0 0 2 2 2 0 DnaB-helicase binding domain of primase DUF668 PF05003.12 CBK20279.2 - 0.097 13.1 0.1 0.23 11.9 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF668) Na_sulph_symp PF00939.19 CBK20280.2 - 8.5e-78 262.5 36.8 1e-77 262.2 36.8 1.0 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CitMHS PF03600.16 CBK20280.2 - 3.7e-44 151.1 48.1 1.8e-40 139.0 14.0 2.4 1 1 1 2 2 2 2 Citrate transporter DctM PF06808.12 CBK20280.2 - 1.6e-06 27.3 30.8 2.6e-06 26.5 13.7 2.3 2 0 0 2 2 2 2 Tripartite ATP-independent periplasmic transporter, DctM component tRNA-synt_2d PF01409.20 CBK20281.2 - 2.2e-83 279.5 0.0 3.1e-83 279.0 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) PheRS_DBD1 PF18552.1 CBK20281.2 - 7e-19 67.3 0.2 1.5e-18 66.3 0.2 1.6 1 0 0 1 1 1 1 PheRS DNA binding domain 1 PheRS_DBD3 PF18553.1 CBK20281.2 - 3.2e-16 59.4 0.0 8.5e-16 58.0 0.0 1.7 1 0 0 1 1 1 1 PheRS DNA binding domain 3 tRNA_synthFbeta PF17759.1 CBK20281.2 - 5.9e-07 29.1 0.0 0.00084 18.8 0.0 2.3 2 0 0 2 2 2 2 Phenylalanyl tRNA synthetase beta chain CLM domain tRNA-synt_2 PF00152.20 CBK20281.2 - 0.00034 19.8 0.2 0.00088 18.4 0.0 1.8 2 0 0 2 2 2 1 tRNA synthetases class II (D, K and N) MarR PF01047.22 CBK20281.2 - 0.0018 18.2 0.0 0.006 16.5 0.0 1.9 1 0 0 1 1 1 1 MarR family RNR_Alpha PF17975.1 CBK20282.2 - 2.3e-40 137.1 0.1 4.9e-40 136.1 0.1 1.6 1 0 0 1 1 1 1 Ribonucleotide reductase alpha domain Ribonuc_red_lgC PF02867.15 CBK20282.2 - 2.6e-10 39.4 0.0 0.0022 16.6 0.0 3.3 3 0 0 3 3 3 3 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.21 CBK20282.2 - 0.00023 21.1 0.0 0.00053 19.9 0.0 1.7 1 0 0 1 1 1 1 Ribonucleotide reductase, all-alpha domain LAP1C PF05609.12 CBK20283.2 - 0.19 10.8 16.0 0.22 10.6 16.0 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) TFIIF_alpha PF05793.12 CBK20283.2 - 0.3 9.6 31.0 0.35 9.4 31.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) RRM_1 PF00076.22 CBK20284.2 - 3.9e-05 23.4 0.0 0.00013 21.8 0.0 1.9 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 CBK20284.2 - 0.029 14.2 0.0 0.041 13.7 0.0 1.2 1 0 0 1 1 1 0 Occluded RNA-recognition motif Ribosomal_S27e PF01667.17 CBK20285.2 - 2e-24 85.0 4.7 2.7e-24 84.6 4.7 1.2 1 0 0 1 1 1 1 Ribosomal protein S27 IBR PF01485.21 CBK20285.2 - 0.0035 17.5 1.4 0.0047 17.1 1.4 1.2 1 0 0 1 1 1 1 IBR domain, a half RING-finger domain TF_Zn_Ribbon PF08271.12 CBK20285.2 - 0.015 14.8 3.2 0.024 14.1 3.2 1.3 1 0 0 1 1 1 0 TFIIB zinc-binding zf-NADH-PPase PF09297.11 CBK20285.2 - 0.076 12.7 1.2 0.12 12.1 0.0 1.9 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain Acetyltransf_1 PF00583.25 CBK20286.2 - 8.4e-16 58.3 0.0 1.1e-15 57.9 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 CBK20286.2 - 4.5e-11 42.8 0.0 5.7e-11 42.4 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 CBK20286.2 - 5.2e-09 36.4 0.0 7.8e-09 35.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 CBK20286.2 - 6.5e-07 29.2 0.0 1e-06 28.6 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 CBK20286.2 - 0.00065 19.8 0.0 0.0012 18.9 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_15 PF17013.5 CBK20286.2 - 0.0049 16.4 0.1 0.0076 15.7 0.1 1.3 1 0 0 1 1 1 1 Putative acetyl-transferase Acetyltransf_3 PF13302.7 CBK20286.2 - 0.024 15.3 0.0 0.04 14.6 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain PanZ PF12568.8 CBK20286.2 - 0.068 12.9 0.1 0.099 12.4 0.1 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain, PanZ MORN PF02493.20 CBK20287.2 - 1.1e-09 37.6 8.7 0.036 14.0 0.2 4.5 4 0 0 4 4 4 3 MORN repeat DUF3887 PF13026.6 CBK20287.2 - 0.031 15.1 0.0 0.13 13.1 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3887) HSP70 PF00012.20 CBK20288.2 - 3e-13 48.8 0.0 5.4e-13 48.0 0.0 1.3 1 1 0 1 1 1 1 Hsp70 protein Histone PF00125.24 CBK20289.2 - 2.3e-52 176.8 3.8 2.7e-52 176.6 3.8 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 CBK20289.2 - 0.00011 22.5 0.1 0.00018 21.8 0.1 1.4 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 CBK20289.2 - 0.00051 20.1 0.1 0.0011 19.0 0.1 1.5 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold PAF PF15715.5 CBK20289.2 - 0.0014 19.2 0.8 0.0018 18.9 0.8 1.2 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CBFD_NFYB_HMF PF00808.23 CBK20289.2 - 0.0098 16.2 0.1 0.02 15.2 0.1 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-T_C PF15511.6 CBK20290.2 - 2.6e-08 34.0 0.1 3.2e-08 33.7 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TAF PF02969.17 CBK20290.2 - 5.2e-05 23.3 0.1 8.2e-05 22.7 0.1 1.5 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) Histone PF00125.24 CBK20290.2 - 6.4e-05 23.3 0.1 9.8e-05 22.7 0.1 1.4 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 CBK20290.2 - 0.00022 21.5 0.1 0.0003 21.1 0.1 1.4 1 1 0 1 1 1 1 CENP-S protein CBFD_NFYB_HMF PF00808.23 CBK20290.2 - 0.00093 19.4 0.1 0.0017 18.6 0.0 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 CBK20290.2 - 0.01 15.9 0.0 0.012 15.7 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 CBK20290.2 - 0.025 14.6 0.0 0.036 14.1 0.0 1.2 1 0 0 1 1 1 0 Bromodomain associated SMN PF06003.12 CBK20291.2 - 1.4e-13 50.8 3.8 4.7e-08 32.6 0.2 2.1 1 1 1 2 2 2 2 Survival motor neuron protein (SMN) TUDOR PF00567.24 CBK20291.2 - 2.4e-05 24.3 1.7 0.011 15.8 0.2 3.0 1 1 2 3 3 3 2 Tudor domain Tudor_3 PF18115.1 CBK20291.2 - 0.03 14.2 0.2 0.15 12.0 0.0 2.2 2 0 0 2 2 2 0 DNA repair protein Crb2 Tudor domain APC_u15 PF16636.5 CBK20291.2 - 2.5 8.6 8.5 1.2 9.6 4.4 2.2 2 0 0 2 2 2 0 Unstructured region on APC between APC_crr regions 5 and 6 Mitoc_mL59 PF18126.1 CBK20292.2 - 4.9e-08 33.3 0.8 4.9e-08 33.3 0.8 2.9 2 1 0 2 2 2 1 Mitochondrial ribosomal protein mL59 Borrelia_P83 PF05262.11 CBK20292.2 - 0.41 9.1 17.2 0.48 8.9 17.2 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein XRN_M PF17846.1 CBK20292.2 - 1.2 8.0 8.7 1.4 7.7 8.7 1.2 1 0 0 1 1 1 0 Xrn1 helical domain Pkinase PF00069.25 CBK20293.2 - 1.6e-26 93.3 0.0 2.8e-20 72.8 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CBK20293.2 - 6.8e-20 71.4 0.0 5.7e-17 61.9 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 CBK20293.2 - 1 8.0 3.2 3.2 6.4 3.2 1.9 1 1 0 1 1 1 0 Fungal protein kinase RCC1 PF00415.18 CBK20294.2 - 2.6e-28 98.4 11.9 2.4e-08 34.4 0.0 6.8 6 1 0 6 6 6 4 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 CBK20294.2 - 6.9e-16 57.6 28.3 1.1e-05 25.0 0.1 6.5 7 0 0 7 7 7 5 Regulator of chromosome condensation (RCC1) repeat DUF3783 PF12646.7 CBK20294.2 - 0.13 12.3 0.0 1.4 9.0 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3783) TFB6 PF17110.5 CBK20294.2 - 0.22 11.2 3.0 0.34 10.6 3.0 1.2 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH Acylphosphatase PF00708.18 CBK20295.2 - 3.2e-07 30.7 0.0 4.2e-07 30.3 0.0 1.2 1 0 0 1 1 1 1 Acylphosphatase WD40 PF00400.32 CBK20296.2 - 1.2e-19 70.3 2.1 0.00035 21.3 0.1 5.7 4 1 0 4 4 4 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBK20296.2 - 8e-07 29.3 0.0 0.00023 21.4 0.0 3.6 2 2 2 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain DUF3123 PF11321.8 CBK20296.2 - 0.0024 18.5 1.6 5 7.8 0.0 3.3 2 1 0 3 3 3 2 Protein of unknown function (DUF3123) WD40_like PF17005.5 CBK20296.2 - 0.0044 16.4 0.0 0.0076 15.6 0.0 1.4 1 0 0 1 1 1 1 WD40-like domain Coatomer_WDAD PF04053.14 CBK20296.2 - 0.024 13.7 0.0 0.034 13.2 0.0 1.1 1 0 0 1 1 1 0 Coatomer WD associated region Frtz PF11768.8 CBK20296.2 - 0.026 12.9 0.1 1.5 7.0 0.0 2.5 1 1 1 3 3 3 0 WD repeat-containing and planar cell polarity effector protein Fritz Sad1_UNC PF07738.13 CBK20297.2 - 0.00032 20.7 0.2 0.67 10.0 0.0 4.0 3 0 0 3 3 3 2 Sad1 / UNC-like C-terminal TES PF08034.11 CBK20297.2 - 0.066 13.5 0.1 0.44 10.9 0.0 2.4 2 0 0 2 2 2 0 Trematode eggshell synthesis protein DNA_pol_B_2 PF03175.13 CBK20298.2 - 2.8e-16 59.5 13.5 2.4e-13 49.8 8.4 2.3 2 0 0 2 2 2 2 DNA polymerase type B, organellar and viral Vac14_Fig4_bd PF11916.8 CBK20299.2 - 9.2e-12 45.0 0.2 1.7e-11 44.1 0.2 1.4 1 0 0 1 1 1 1 Vacuolar protein 14 C-terminal Fig4p binding Cnd1 PF12717.7 CBK20299.2 - 1.3e-08 35.1 3.8 0.022 14.8 0.1 3.6 2 2 1 3 3 3 3 non-SMC mitotic condensation complex subunit 1 CLASP_N PF12348.8 CBK20299.2 - 9.7e-08 31.8 0.1 6.8e-07 29.1 0.0 2.3 2 1 1 3 3 3 1 CLASP N terminal HEAT_2 PF13646.6 CBK20299.2 - 1.9e-07 31.3 1.1 0.083 13.3 0.0 3.8 3 1 0 3 3 3 3 HEAT repeats HEAT PF02985.22 CBK20299.2 - 4.6e-06 26.4 2.1 0.16 12.3 0.1 5.1 6 0 0 6 6 6 1 HEAT repeat RasGEF_N_2 PF14663.6 CBK20299.2 - 0.00079 19.8 1.1 1.6 9.2 0.1 3.5 3 0 0 3 3 3 2 Rapamycin-insensitive companion of mTOR RasGEF_N domain Dopey_N PF04118.14 CBK20299.2 - 0.00099 18.3 1.8 0.43 9.7 0.4 2.7 1 1 2 3 3 3 2 Dopey, N-terminal HEAT_EZ PF13513.6 CBK20299.2 - 0.0029 18.1 0.5 1.3 9.6 0.0 3.1 3 0 0 3 3 3 1 HEAT-like repeat ParcG PF10274.9 CBK20299.2 - 0.007 16.5 3.7 0.39 10.8 0.0 3.7 2 2 1 4 4 4 1 Parkin co-regulated protein Proteasom_PSMB PF10508.9 CBK20299.2 - 0.039 12.5 0.4 4.5 5.7 0.1 2.2 2 0 0 2 2 2 0 Proteasome non-ATPase 26S subunit NopRA1 PF16201.5 CBK20299.2 - 0.045 13.3 0.1 9.3 5.8 0.0 2.7 2 1 0 3 3 3 0 Nucleolar pre-ribosomal-associated protein 1 Vac14_Fab1_bd PF12755.7 CBK20300.2 - 2.9e-32 111.1 0.3 9.7e-32 109.5 0.2 1.8 2 0 0 2 2 2 1 Vacuolar 14 Fab1-binding region HEAT PF02985.22 CBK20300.2 - 2.2e-08 33.6 0.1 0.00028 20.9 0.0 3.5 4 0 0 4 4 4 2 HEAT repeat Tti2 PF10521.9 CBK20300.2 - 4.4e-05 23.2 0.0 5.9e-05 22.8 0.0 1.2 1 1 0 1 1 1 1 Tti2 family HEAT_EZ PF13513.6 CBK20300.2 - 0.00046 20.6 0.0 0.0017 18.8 0.0 1.8 2 0 0 2 2 2 1 HEAT-like repeat HEAT_2 PF13646.6 CBK20300.2 - 0.0027 18.1 0.0 0.15 12.5 0.0 2.2 1 1 1 2 2 2 2 HEAT repeats PPL4 PF18188.1 CBK20300.2 - 0.012 15.6 0.7 0.02 14.8 0.4 1.6 2 0 0 2 2 2 0 Prim-pol 4 TAF6_C PF07571.13 CBK20300.2 - 0.016 15.5 0.1 0.45 10.9 0.0 2.1 1 1 0 2 2 2 0 TAF6 C-terminal HEAT repeat domain CLASP_N PF12348.8 CBK20300.2 - 0.018 14.6 0.0 0.023 14.3 0.0 1.2 1 0 0 1 1 1 0 CLASP N terminal Adaptin_N PF01602.20 CBK20300.2 - 0.019 13.6 0.2 0.34 9.4 0.1 1.9 1 1 1 2 2 2 0 Adaptin N terminal region Cnd1 PF12717.7 CBK20300.2 - 0.039 14.0 0.0 0.34 10.9 0.0 2.0 1 1 1 2 2 2 0 non-SMC mitotic condensation complex subunit 1 WAPL PF07814.13 CBK20300.2 - 0.11 11.2 0.3 0.17 10.6 0.3 1.2 1 0 0 1 1 1 0 Wings apart-like protein regulation of heterochromatin Thioredoxin PF00085.20 CBK20301.2 - 7.4e-27 93.3 0.1 1.9e-26 92.1 0.0 1.6 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_2 PF13098.6 CBK20301.2 - 1.1e-05 25.9 0.0 3.4e-05 24.2 0.0 1.8 1 1 0 1 1 1 1 Thioredoxin-like domain WD40 PF00400.32 CBK20301.2 - 2.7e-05 24.8 0.3 0.00014 22.5 0.0 2.4 2 0 0 2 2 2 1 WD domain, G-beta repeat Thioredoxin_8 PF13905.6 CBK20301.2 - 0.001 19.4 0.0 0.43 11.0 0.0 2.7 1 1 1 2 2 2 2 Thioredoxin-like TraF PF13728.6 CBK20301.2 - 0.0036 17.1 0.0 0.0057 16.5 0.0 1.2 1 0 0 1 1 1 1 F plasmid transfer operon protein OST3_OST6 PF04756.13 CBK20301.2 - 0.012 15.0 0.0 0.019 14.3 0.0 1.2 1 0 0 1 1 1 0 OST3 / OST6 family, transporter family Thioredoxin_7 PF13899.6 CBK20301.2 - 0.015 15.4 0.1 0.037 14.2 0.1 1.6 1 1 0 1 1 1 0 Thioredoxin-like Thioredoxin_9 PF14595.6 CBK20301.2 - 0.022 14.5 0.0 0.035 13.9 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin Thioredoxin_3 PF13192.6 CBK20301.2 - 0.044 13.8 0.0 0.085 12.9 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin domain HyaE PF07449.11 CBK20301.2 - 0.09 12.8 0.0 0.17 11.9 0.0 1.3 1 0 0 1 1 1 0 Hydrogenase-1 expression protein HyaE Thioredoxin_6 PF13848.6 CBK20301.2 - 0.15 12.0 0.0 0.25 11.2 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin-like domain Arf PF00025.21 CBK20302.2 - 5.6e-60 201.8 0.0 6.3e-60 201.6 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.20 CBK20302.2 - 1.8e-13 50.4 0.1 1.9e-10 40.4 0.0 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.22 CBK20302.2 - 1.1e-11 44.5 0.0 8.9e-10 38.4 0.0 2.1 1 1 1 2 2 2 1 Ras family Roc PF08477.13 CBK20302.2 - 4.2e-10 39.9 0.0 3.6e-09 36.9 0.0 2.2 2 1 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 CBK20302.2 - 2.1e-08 34.3 0.0 6.9e-08 32.6 0.0 1.8 1 1 1 2 2 2 1 50S ribosome-binding GTPase SRPRB PF09439.10 CBK20302.2 - 8.4e-07 28.6 0.0 1.1e-06 28.2 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 CBK20302.2 - 9.6e-07 28.4 0.0 1.8e-06 27.5 0.0 1.4 1 1 1 2 2 2 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 CBK20302.2 - 9.2e-05 22.1 0.0 0.013 15.0 0.0 2.3 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain cobW PF02492.19 CBK20302.2 - 0.027 14.1 0.1 0.42 10.2 0.0 2.0 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Septin PF00735.18 CBK20302.2 - 0.044 13.0 0.1 8.6 5.5 0.0 2.6 2 1 1 3 3 3 0 Septin AAA_29 PF13555.6 CBK20302.2 - 0.063 13.0 0.0 0.17 11.7 0.0 1.7 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_23 PF13476.6 CBK20302.2 - 0.071 13.6 0.0 0.09 13.3 0.0 1.2 1 0 0 1 1 1 0 AAA domain PduV-EutP PF10662.9 CBK20302.2 - 0.21 11.3 0.0 0.76 9.5 0.0 1.9 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Glyco_transf_8 PF01501.20 CBK20303.2 - 1.4e-12 47.8 0.5 2.9e-09 36.8 0.2 2.0 2 0 0 2 2 2 2 Glycosyl transferase family 8 Mannosyl_trans3 PF11051.8 CBK20303.2 - 0.00044 19.7 0.0 0.00059 19.3 0.0 1.2 1 0 0 1 1 1 1 Mannosyltransferase putative Ribosomal_L7Ae PF01248.26 CBK20303.2 - 0.15 11.8 0.0 0.24 11.1 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family HSP70 PF00012.20 CBK20304.2 - 1.6e-17 62.9 0.0 1.3e-16 59.9 0.0 1.9 1 1 0 1 1 1 1 Hsp70 protein MMR_HSR1_Xtn PF16897.5 CBK20306.2 - 9.1e-38 128.5 0.3 2e-37 127.4 0.3 1.6 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain MMR_HSR1 PF01926.23 CBK20306.2 - 4.4e-20 71.9 0.0 1.2e-19 70.5 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase TGS PF02824.21 CBK20306.2 - 3.8e-15 55.7 0.0 7.2e-15 54.8 0.0 1.5 1 0 0 1 1 1 1 TGS domain FeoB_N PF02421.18 CBK20306.2 - 1.4e-09 37.6 0.0 2.8e-09 36.7 0.0 1.5 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 CBK20306.2 - 5.4e-05 23.3 0.2 0.02 14.9 0.0 2.7 3 0 0 3 3 3 2 Dynamin family GPAT_N PF14829.6 CBK20306.2 - 0.035 14.1 0.2 0.078 13.0 0.2 1.5 1 0 0 1 1 1 0 Glycerol-3-phosphate acyltransferase N-terminal Roc PF08477.13 CBK20306.2 - 0.05 13.8 0.0 0.29 11.4 0.0 2.3 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase AAA_28 PF13521.6 CBK20306.2 - 0.051 13.8 0.1 0.27 11.5 0.1 2.2 2 0 0 2 2 2 0 AAA domain Proteasome PF00227.26 CBK20307.2 - 1.3e-52 178.0 0.0 1.6e-52 177.8 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 CBK20307.2 - 5.2e-14 51.6 0.2 1e-13 50.6 0.2 1.5 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature DUF3842 PF12953.7 CBK20307.2 - 0.097 13.1 0.5 1.4 9.3 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3842) CS PF04969.16 CBK20308.2 - 8.6e-11 42.7 0.1 6.2e-10 40.0 0.1 2.1 1 1 0 1 1 1 1 CS domain Ras PF00071.22 CBK20309.2 - 2.5e-59 199.5 0.4 2.9e-59 199.3 0.4 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CBK20309.2 - 2.4e-33 114.9 0.1 3.4e-33 114.4 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CBK20309.2 - 6.6e-16 58.3 0.0 8e-16 58.0 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 CBK20309.2 - 4.7e-07 29.4 0.1 5.9e-07 29.1 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 CBK20309.2 - 7.4e-06 26.0 0.1 1.1e-05 25.5 0.1 1.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 CBK20309.2 - 1.3e-05 24.8 0.2 0.00023 20.7 0.2 2.0 1 1 0 1 1 1 1 Ferrous iron transport protein B GTP_EFTU PF00009.27 CBK20309.2 - 0.00034 20.2 0.0 0.002 17.7 0.0 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain TniB PF05621.11 CBK20309.2 - 0.0041 16.5 0.0 0.0067 15.8 0.0 1.4 1 0 0 1 1 1 1 Bacterial TniB protein RsgA_GTPase PF03193.16 CBK20309.2 - 0.0054 16.7 0.0 3.4 7.5 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase SRPRB PF09439.10 CBK20309.2 - 0.016 14.7 0.0 0.018 14.5 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit ATPase_2 PF01637.18 CBK20309.2 - 0.056 13.3 0.1 0.072 13.0 0.1 1.4 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea PduV-EutP PF10662.9 CBK20309.2 - 0.073 12.8 0.0 1.6 8.5 0.0 2.2 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation DHHC PF01529.20 CBK20310.2 - 9.6e-38 129.3 11.9 9.6e-38 129.3 11.9 1.4 2 0 0 2 2 2 1 DHHC palmitoyltransferase CARM1 PF11531.8 CBK20310.2 - 1 9.6 3.5 1.6 8.9 0.9 2.1 1 1 1 2 2 2 0 Coactivator-associated arginine methyltransferase 1 N terminal WD40 PF00400.32 CBK20311.2 - 2e-24 85.4 17.9 7.8e-07 29.7 0.3 6.9 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBK20311.2 - 2.7e-14 53.2 1.0 4.8e-06 26.8 0.0 4.9 2 2 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Frtz PF11768.8 CBK20311.2 - 0.0028 16.0 0.0 0.44 8.8 0.0 2.4 2 0 0 2 2 2 2 WD repeat-containing and planar cell polarity effector protein Fritz Ge1_WD40 PF16529.5 CBK20311.2 - 0.011 14.7 0.1 10 5.0 0.0 3.8 3 2 1 5 5 5 0 WD40 region of Ge1, enhancer of mRNA-decapping protein DUF4930 PF16284.5 CBK20311.2 - 0.045 13.7 0.0 0.088 12.8 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4930) IKI3 PF04762.12 CBK20311.2 - 0.11 10.4 0.9 2.4 6.0 0.1 2.6 3 0 0 3 3 3 0 IKI3 family WD40 PF00400.32 CBK20312.2 - 8.2e-06 26.5 1.3 5.9e-05 23.8 0.7 2.5 2 0 0 2 2 2 1 WD domain, G-beta repeat PQQ_3 PF13570.6 CBK20312.2 - 0.0051 17.3 1.5 0.43 11.1 0.1 2.4 2 0 0 2 2 2 2 PQQ-like domain HSP70 PF00012.20 CBK20313.2 - 1.7e-65 221.4 0.0 4.3e-65 220.1 0.0 1.5 1 1 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 CBK20313.2 - 8.8e-11 41.2 0.1 0.00011 21.2 0.0 3.0 3 0 0 3 3 3 2 MreB/Mbl protein DDR PF08841.10 CBK20313.2 - 0.0099 14.9 0.0 0.86 8.5 0.0 2.2 2 0 0 2 2 2 2 Diol dehydratase reactivase ATPase-like domain Band_7 PF01145.25 CBK20314.2 - 3.2e-23 82.6 1.5 3.2e-23 82.6 1.5 1.4 2 0 0 2 2 2 1 SPFH domain / Band 7 family Carboxyl_trans PF01039.22 CBK20315.2 - 1.9e-138 462.2 0.0 2.3e-138 461.9 0.0 1.0 1 0 0 1 1 1 1 Carboxyl transferase domain CRAL_TRIO PF00650.20 CBK20316.2 - 2.1e-26 92.6 0.2 3.3e-26 91.9 0.2 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 CBK20316.2 - 0.03 14.5 0.0 0.05 13.8 0.0 1.3 1 0 0 1 1 1 0 Divergent CRAL/TRIO domain RNA_pol_Rpb2_6 PF00562.28 CBK20317.2 - 4.9e-111 371.6 0.0 1.2e-110 370.2 0.0 1.6 1 1 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 CBK20317.2 - 4.8e-33 114.4 0.0 7.2e-33 113.8 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_3 PF04565.16 CBK20317.2 - 1.6e-27 95.5 0.0 3.1e-27 94.6 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_7 PF04560.20 CBK20317.2 - 6.1e-23 81.0 0.1 1.5e-22 79.7 0.1 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_2 PF04561.14 CBK20317.2 - 1e-22 80.7 0.1 1.6e-22 80.1 0.1 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpa2_4 PF06883.12 CBK20317.2 - 1.1e-14 54.1 0.0 2.9e-14 52.8 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase I, Rpa2 specific domain RNA_pol_Rpb2_4 PF04566.13 CBK20317.2 - 0.021 15.1 0.0 0.048 14.0 0.0 1.7 1 0 0 1 1 1 0 RNA polymerase Rpb2, domain 4 UL45 PF05473.12 CBK20318.2 - 0.015 15.0 0.1 0.015 15.0 0.1 3.9 3 1 0 3 3 3 0 UL45 protein, carbohydrate-binding C-type lectin-like Mito_carr PF00153.27 CBK20319.2 - 1.5e-27 95.3 6.2 1.6e-09 37.6 0.1 5.0 3 2 2 5 5 5 5 Mitochondrial carrier protein Ribosomal_S11 PF00411.19 CBK20320.2 - 8.3e-47 158.2 1.2 1e-46 157.8 1.2 1.1 1 0 0 1 1 1 1 Ribosomal protein S11 CBM_25 PF03423.13 CBK20320.2 - 0.014 15.6 0.1 0.042 14.1 0.1 1.7 2 0 0 2 2 2 0 Carbohydrate binding domain (family 25) DUF2252 PF10009.9 CBK20320.2 - 0.048 12.7 0.0 0.058 12.5 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2252) Condensin2nSMC PF12422.8 CBK20321.2 - 7.5e-18 65.1 2.0 7.6e-17 61.9 0.1 2.4 3 0 0 3 3 3 1 Condensin II non structural maintenance of chromosomes subunit Cnd1 PF12717.7 CBK20321.2 - 5.5e-06 26.5 1.8 0.003 17.6 0.2 3.0 1 1 2 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 CBK20321.2 - 6e-06 26.1 0.9 0.67 10.4 0.0 4.3 4 0 0 4 4 4 2 HEAT repeat Adaptin_N PF01602.20 CBK20321.2 - 0.0099 14.5 0.3 0.07 11.7 0.0 1.9 1 1 1 2 2 2 1 Adaptin N terminal region Toxin_4 PF00706.17 CBK20321.2 - 0.053 13.9 0.0 0.091 13.2 0.0 1.3 1 0 0 1 1 1 0 Anenome neurotoxin RNA_pol_A_bac PF01000.26 CBK20322.2 - 3.9e-25 88.4 0.5 1.8e-24 86.3 0.0 2.2 2 1 1 3 3 3 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.24 CBK20322.2 - 1.6e-19 69.0 0.0 2.8e-19 68.3 0.0 1.4 1 1 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Fer4_9 PF13187.6 CBK20322.2 - 0.015 15.4 0.3 0.046 13.9 0.3 1.8 1 0 0 1 1 1 0 4Fe-4S dicluster domain RNA_pol_L_2 PF13656.6 CBK20322.2 - 0.046 13.5 0.0 3.2 7.6 0.0 2.5 2 0 0 2 2 2 0 RNA polymerase Rpb3/Rpb11 dimerisation domain ETF_QO PF05187.13 CBK20322.2 - 0.13 12.4 0.2 0.51 10.5 0.0 2.0 2 0 0 2 2 2 0 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S G-patch PF01585.23 CBK20323.2 - 1.2e-11 44.2 4.0 2.7e-11 43.2 4.0 1.6 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 CBK20323.2 - 0.00065 19.7 0.9 0.00065 19.7 0.9 1.8 2 0 0 2 2 2 1 G-patch domain AAA_34 PF13872.6 CBK20324.2 - 2.4e-110 368.2 0.0 4.3e-110 367.3 0.0 1.4 1 0 0 1 1 1 1 P-loop containing NTP hydrolase pore-1 Helicase_C_4 PF13871.6 CBK20324.2 - 1e-78 264.8 0.1 6.9e-77 258.8 0.4 2.8 2 1 0 2 2 2 1 C-terminal domain on Strawberry notch homologue MIS13 PF08202.11 CBK20324.2 - 0.0044 16.3 0.4 0.0044 16.3 0.4 1.9 2 0 0 2 2 2 1 Mis12-Mtw1 protein family Helicase_C PF00271.31 CBK20324.2 - 0.036 14.4 0.1 0.1 12.9 0.1 1.8 1 0 0 1 1 1 0 Helicase conserved C-terminal domain VASP_tetra PF08776.11 CBK20324.2 - 0.085 12.4 0.2 0.18 11.4 0.2 1.5 1 0 0 1 1 1 0 VASP tetramerisation domain ORC_WH_C PF18137.1 CBK20324.2 - 0.3 11.1 1.9 0.27 11.3 0.1 1.8 2 0 0 2 2 2 0 Origin recognition complex winged helix C-terminal DUF4570 PF15134.6 CBK20324.2 - 0.7 9.9 5.2 0.38 10.8 0.8 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4570) E3_UFM1_ligase PF09743.9 CBK20325.2 - 1.6e-74 251.0 3.5 2.6e-74 250.3 3.1 1.5 2 0 0 2 2 2 1 E3 UFM1-protein ligase 1 HTH_24 PF13412.6 CBK20325.2 - 0.0034 16.9 0.9 0.033 13.8 0.1 2.8 3 0 0 3 3 3 1 Winged helix-turn-helix DNA-binding HTH_27 PF13463.6 CBK20325.2 - 0.068 13.7 0.7 17 6.0 0.1 3.0 3 0 0 3 3 3 0 Winged helix DNA-binding domain HTH_11 PF08279.12 CBK20325.2 - 0.089 12.8 0.3 0.45 10.5 0.0 2.3 2 0 0 2 2 2 0 HTH domain UPF0193 PF05250.11 CBK20325.2 - 0.12 12.2 0.1 0.21 11.3 0.1 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0193) DUF413 PF04219.12 CBK20326.2 - 0.074 13.1 0.0 0.27 11.3 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function, DUF WD40 PF00400.32 CBK20327.2 - 5.6e-47 156.8 18.2 1.2e-10 41.8 0.1 7.2 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBK20327.2 - 4.1e-10 39.8 4.5 0.0063 16.8 0.0 5.5 2 2 4 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 CBK20327.2 - 1.3e-06 27.4 6.9 0.015 14.0 0.1 5.0 3 1 1 5 5 5 3 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 CBK20327.2 - 8.3e-06 25.0 0.3 0.04 12.9 0.0 3.6 2 1 2 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein PQQ_2 PF13360.6 CBK20327.2 - 0.0064 16.1 1.7 0.083 12.5 0.0 2.3 2 1 0 2 2 2 1 PQQ-like domain DUF1513 PF07433.11 CBK20327.2 - 0.0094 15.1 0.3 0.97 8.4 0.1 3.0 1 1 3 4 4 4 1 Protein of unknown function (DUF1513) Cytochrom_D1 PF02239.16 CBK20327.2 - 0.02 13.5 0.0 0.94 7.9 0.0 2.9 2 2 1 3 3 3 0 Cytochrome D1 heme domain PQQ_3 PF13570.6 CBK20327.2 - 0.075 13.5 0.7 18 6.0 0.1 3.8 3 1 0 3 3 3 0 PQQ-like domain Ribosomal_L37e PF01907.19 CBK20328.2 - 3.1e-27 94.5 11.2 3.1e-27 94.5 11.2 1.6 2 0 0 2 2 2 1 Ribosomal protein L37e HypA PF01155.19 CBK20328.2 - 0.034 14.1 0.6 0.047 13.7 0.6 1.2 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-RING_10 PF16685.5 CBK20328.2 - 0.09 12.9 1.9 0.12 12.5 1.9 1.2 1 0 0 1 1 1 0 zinc RING finger of MSL2 LRR_6 PF13516.6 CBK20329.2 - 8.8e-09 34.7 0.2 0.00054 19.8 0.2 2.8 2 0 0 2 2 2 2 Leucine Rich repeat LRR_8 PF13855.6 CBK20329.2 - 0.00017 21.3 3.9 0.63 9.8 0.2 3.4 2 1 1 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 CBK20329.2 - 0.00098 19.5 9.3 0.0032 17.8 0.9 3.2 1 1 1 2 2 2 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 CBK20329.2 - 0.56 11.0 10.3 6.3 7.8 0.8 4.1 3 1 1 4 4 4 0 Leucine Rich Repeat Ovate PF04844.13 CBK20330.2 - 0.047 13.7 0.9 0.083 12.9 0.1 1.9 1 1 1 2 2 2 0 Transcriptional repressor, ovate WD40 PF00400.32 CBK20332.2 - 5.9e-09 36.4 1.4 0.12 13.3 0.0 3.8 3 0 0 3 3 3 3 WD domain, G-beta repeat NT5C PF06941.12 CBK20334.2 - 7.6e-11 42.2 0.1 9.3e-11 41.9 0.1 1.2 1 0 0 1 1 1 1 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C) HAD_2 PF13419.6 CBK20334.2 - 0.0016 18.6 0.0 0.0027 17.8 0.0 1.5 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Trehalose_PPase PF02358.16 CBK20334.2 - 0.073 12.2 0.0 0.11 11.6 0.0 1.2 1 0 0 1 1 1 0 Trehalose-phosphatase zf-Tim10_DDP PF02953.15 CBK20335.2 - 4.9e-11 42.1 0.7 6.6e-11 41.7 0.7 1.3 1 0 0 1 1 1 1 Tim10/DDP family zinc finger Pro_isomerase PF00160.21 CBK20336.2 - 8.6e-44 149.6 0.1 9.6e-44 149.4 0.1 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD S_100 PF01023.19 CBK20337.2 - 0.0088 15.7 0.3 0.068 12.9 0.0 2.2 2 0 0 2 2 2 1 S-100/ICaBP type calcium binding domain Adap_comp_sub PF00928.21 CBK20338.2 - 2.4e-81 273.0 0.0 3e-81 272.7 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 CBK20338.2 - 3.5e-09 36.7 0.2 6.3e-09 35.9 0.2 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain muHD PF10291.9 CBK20338.2 - 0.0028 17.2 0.0 0.0044 16.5 0.0 1.3 1 0 0 1 1 1 1 Muniscin C-terminal mu homology domain Longin PF13774.6 CBK20338.2 - 0.062 13.4 0.1 0.14 12.2 0.1 1.6 1 0 0 1 1 1 0 Regulated-SNARE-like domain TRAPPC9-Trs120 PF08626.11 CBK20339.2 - 2.7e-13 48.3 0.1 2.4e-09 35.2 0.0 2.5 3 0 0 3 3 3 2 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit GATase_6 PF13522.6 CBK20340.2 - 1.1e-12 48.3 0.0 4.9e-12 46.2 0.0 2.0 1 1 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.6 CBK20340.2 - 7.7e-11 42.0 0.0 2.4e-10 40.4 0.0 1.8 1 1 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.6 CBK20340.2 - 5e-05 22.3 0.0 7.2e-05 21.8 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Pribosyltran PF00156.27 CBK20340.2 - 0.0025 17.3 0.0 0.0042 16.6 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain GATase_2 PF00310.21 CBK20340.2 - 0.0028 16.4 0.1 0.22 10.2 0.0 2.5 2 1 1 3 3 3 2 Glutamine amidotransferases class-II Cwf_Cwc_15 PF04889.12 CBK20341.2 - 7.1e-38 130.7 23.2 1.8e-35 122.9 23.2 2.0 1 1 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein RD3 PF14473.6 CBK20341.2 - 0.011 15.5 1.5 0.02 14.7 1.5 1.4 1 0 0 1 1 1 0 RD3 protein Hid1 PF12722.7 CBK20341.2 - 0.13 10.4 4.5 0.15 10.2 4.5 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein YL1 PF05764.13 CBK20341.2 - 0.17 11.9 13.1 0.22 11.6 13.1 1.2 1 0 0 1 1 1 0 YL1 nuclear protein CDC45 PF02724.14 CBK20341.2 - 6.7 4.9 10.4 7.3 4.7 10.4 1.1 1 0 0 1 1 1 0 CDC45-like protein Vps39_2 PF10367.9 CBK20342.2 - 1e-20 74.2 1.4 2.6e-20 72.9 0.0 2.3 3 0 0 3 3 3 1 Vacuolar sorting protein 39 domain 2 Clathrin PF00637.20 CBK20342.2 - 0.00019 21.3 3.4 0.00032 20.6 0.3 2.5 3 0 0 3 3 3 1 Region in Clathrin and VPS Rdx PF10262.9 CBK20342.2 - 0.08 13.2 0.2 0.29 11.4 0.0 2.1 2 0 0 2 2 2 0 Rdx family CNH PF00780.22 CBK20343.2 - 1e-20 74.5 0.0 1.7e-20 73.8 0.0 1.3 1 0 0 1 1 1 1 CNH domain HPS3_N PF14761.6 CBK20343.2 - 0.046 13.3 1.6 0.17 11.4 0.0 2.7 3 1 1 4 4 4 0 Hermansky-Pudlak syndrome 3 TPR_1 PF00515.28 CBK20343.2 - 0.19 11.6 0.7 0.66 9.9 0.1 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat He_PIG PF05345.12 CBK20344.2 - 5e-16 58.6 31.3 5.3e-05 23.3 0.1 5.6 5 1 0 5 5 5 4 Putative Ig domain DUF11 PF01345.18 CBK20344.2 - 1.3e-07 31.8 0.7 0.85 10.0 0.0 4.5 2 2 0 3 3 3 3 Domain of unknown function DUF11 I-set PF07679.16 CBK20344.2 - 1.4e-05 25.0 7.6 2.1 8.5 0.1 4.5 4 0 0 4 4 4 3 Immunoglobulin I-set domain HRM PF02793.22 CBK20344.2 - 0.0033 17.7 15.0 0.73 10.2 0.3 5.2 5 0 0 5 5 5 2 Hormone receptor domain ComP_DUS PF16732.5 CBK20344.2 - 0.052 14.4 3.0 45 5.0 0.0 3.9 4 0 0 4 4 4 0 Type IV minor pilin ComP, DNA uptake sequence receptor DUF2207 PF09972.9 CBK20344.2 - 0.089 11.5 0.0 0.16 10.7 0.0 1.4 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF3185 PF11381.8 CBK20344.2 - 0.09 12.8 4.8 0.25 11.4 4.8 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3185) cEGF PF12662.7 CBK20344.2 - 0.64 10.0 7.0 3.2 7.8 0.0 3.6 3 0 0 3 3 3 0 Complement Clr-like EGF-like Arch_flagellin PF01917.16 CBK20344.2 - 2.4 8.3 10.0 9.6 6.4 4.5 3.4 2 1 0 2 2 2 0 Archaebacterial flagellin DUF5305 PF17231.2 CBK20344.2 - 4.8 6.5 6.5 0.92 8.9 0.1 2.9 4 0 0 4 4 4 0 Family of unknown function (DUF5305) DEAD_2 PF06733.15 CBK20345.2 - 2.4e-10 40.3 4.4 2.5e-10 40.3 2.5 1.8 2 0 0 2 2 2 1 DEAD_2 ResIII PF04851.15 CBK20345.2 - 1.2e-07 32.0 0.0 1.4e-07 31.6 0.0 1.1 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 CBK20345.2 - 0.00067 19.5 0.0 0.00078 19.3 0.0 1.1 1 0 0 1 1 1 1 DEAD/DEAH box helicase T2SSE PF00437.20 CBK20345.2 - 0.02 14.0 0.0 0.026 13.6 0.0 1.1 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_11 PF13086.6 CBK20345.2 - 0.047 13.5 0.0 0.053 13.3 0.0 1.1 1 0 0 1 1 1 0 AAA domain DEAD_2 PF06733.15 CBK20346.2 - 2.4e-20 72.9 0.1 3.5e-20 72.4 0.1 1.2 1 0 0 1 1 1 1 DEAD_2 Hormone_1 PF00103.20 CBK20346.2 - 0.005 16.6 0.1 0.007 16.1 0.1 1.2 1 0 0 1 1 1 1 Somatotropin hormone family YAF2_RYBP PF17219.3 CBK20346.2 - 0.17 11.5 0.0 0.34 10.5 0.0 1.5 1 0 0 1 1 1 0 Yaf2/RYBP C-terminal binding motif Helicase_C_2 PF13307.6 CBK20347.2 - 7.2e-38 130.4 0.0 1e-37 130.0 0.0 1.2 1 0 0 1 1 1 1 Helicase C-terminal domain PAD_porph PF04371.15 CBK20348.2 - 6e-123 410.2 0.0 6.8e-123 410.0 0.0 1.0 1 0 0 1 1 1 1 Porphyromonas-type peptidyl-arginine deiminase DBP10CT PF08147.12 CBK20349.2 - 5.4e-15 55.4 4.3 1.6e-14 53.9 4.3 1.9 1 0 0 1 1 1 1 DBP10CT (NUC160) domain DEAD PF00270.29 CBK20351.2 - 9.5e-31 106.9 0.0 2.1e-26 92.8 0.0 3.6 3 1 0 3 3 3 2 DEAD/DEAH box helicase Helicase_C PF00271.31 CBK20351.2 - 1.1e-24 86.9 0.3 8e-24 84.1 0.0 2.4 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ERCC3_RAD25_C PF16203.5 CBK20351.2 - 0.00039 19.7 0.0 0.00076 18.8 0.0 1.4 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase SRPRB PF09439.10 CBK20352.2 - 7.6e-27 93.9 0.0 9.9e-27 93.5 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Arf PF00025.21 CBK20352.2 - 6.7e-09 35.4 0.0 9.6e-09 34.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 CBK20352.2 - 2.5e-06 27.7 0.0 3.8e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Gtr1_RagA PF04670.12 CBK20352.2 - 1.5e-05 24.5 0.0 1.8e-05 24.2 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.20 CBK20352.2 - 0.00069 18.9 0.1 0.43 9.7 0.0 2.1 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.22 CBK20352.2 - 0.0028 17.3 0.0 0.0042 16.7 0.0 1.2 1 0 0 1 1 1 1 Ras family GTP_EFTU PF00009.27 CBK20352.2 - 0.0045 16.6 0.0 0.045 13.3 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain CdiA_C PF18451.1 CBK20352.2 - 0.11 12.7 0.0 0.19 12.0 0.0 1.4 1 0 0 1 1 1 0 Contact-dependent growth inhibition CdiA C-terminal domain TIM PF00121.18 CBK20353.2 - 3.1e-83 278.9 0.7 3.9e-83 278.6 0.1 1.5 2 0 0 2 2 2 1 Triosephosphate isomerase Gp_dh_C PF02800.20 CBK20353.2 - 2.3e-67 225.5 0.0 1.4e-66 222.9 0.0 2.1 2 0 0 2 2 2 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 CBK20353.2 - 1.6e-34 118.2 0.0 4e-34 117.0 0.0 1.7 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain CutC PF03932.14 CBK20353.2 - 0.042 13.3 0.0 0.091 12.2 0.0 1.5 1 0 0 1 1 1 0 CutC family Rib_5-P_isom_A PF06026.14 CBK20354.2 - 9.7e-62 207.6 0.2 1.2e-61 207.4 0.2 1.1 1 0 0 1 1 1 1 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) DeoRC PF00455.22 CBK20354.2 - 0.0017 18.4 0.2 0.0054 16.7 0.0 1.8 2 0 0 2 2 2 1 DeoR C terminal sensor domain VID27_PH PF17747.1 CBK20355.2 - 0.0035 17.6 0.2 0.0036 17.6 0.2 1.1 1 0 0 1 1 1 1 VID27 PH-like domain eIF3_N PF09440.10 CBK20355.2 - 0.14 12.6 0.0 0.21 12.0 0.0 1.3 1 0 0 1 1 1 0 eIF3 subunit 6 N terminal domain eIF3_N PF09440.10 CBK20356.2 - 3.2e-13 50.3 0.2 1.6e-12 48.0 0.0 2.2 2 1 0 2 2 2 1 eIF3 subunit 6 N terminal domain GHMP_kinases_C PF08544.13 CBK20357.2 - 7.9e-09 35.8 0.2 1.5e-08 34.8 0.2 1.5 1 1 0 1 1 1 1 GHMP kinases C terminal CSTF2_hinge PF14327.6 CBK20357.2 - 0.12 12.9 0.0 0.2 12.1 0.0 1.4 1 0 0 1 1 1 0 Hinge domain of cleavage stimulation factor subunit 2 TYW3 PF02676.14 CBK20358.2 - 4.4e-55 186.4 0.0 5.6e-55 186.0 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase TYW3 He_PIG PF05345.12 CBK20360.2 - 4.5e-05 23.6 0.1 0.00014 21.9 0.1 1.9 1 0 0 1 1 1 1 Putative Ig domain Sushi PF00084.20 CBK20360.2 - 0.27 11.9 3.1 0.39 11.4 0.3 2.5 2 0 0 2 2 2 0 Sushi repeat (SCR repeat) LRR_4 PF12799.7 CBK20361.2 - 0.00025 21.3 3.4 0.082 13.4 0.6 3.4 3 1 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CBK20361.2 - 0.0019 18.0 1.7 0.23 11.2 0.6 2.7 2 0 0 2 2 2 2 Leucine rich repeat Actin PF00022.19 CBK20362.2 - 4.1e-139 463.7 0.0 4.1e-138 460.4 0.0 1.9 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.13 CBK20362.2 - 0.0087 14.9 0.0 0.03 13.1 0.0 1.9 2 0 0 2 2 2 1 MreB/Mbl protein Methyltransf_29 PF03141.16 CBK20362.2 - 0.043 12.4 0.0 0.058 11.9 0.0 1.2 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase POR_N PF01855.19 CBK20363.2 - 2.2e-72 243.5 0.4 6.3e-72 242.0 0.1 1.9 2 0 0 2 2 2 1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg FAD_binding_1 PF00667.20 CBK20363.2 - 1.8e-41 142.2 0.0 3.2e-41 141.4 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 CBK20363.2 - 2.9e-25 89.2 0.1 7e-25 87.9 0.1 1.7 1 0 0 1 1 1 1 Flavodoxin POR PF01558.18 CBK20363.2 - 2.2e-22 80.0 0.0 5.9e-22 78.6 0.0 1.8 1 0 0 1 1 1 1 Pyruvate ferredoxin/flavodoxin oxidoreductase EKR PF10371.9 CBK20363.2 - 8.7e-19 67.1 0.6 2.2e-18 65.8 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function PFOR_II PF17147.4 CBK20363.2 - 7.2e-12 45.5 0.0 2.5e-11 43.8 0.0 2.0 1 0 0 1 1 1 1 Pyruvate:ferredoxin oxidoreductase core domain II Fer4_7 PF12838.7 CBK20363.2 - 5.1e-08 33.4 8.1 2.5e-07 31.2 8.3 2.3 1 1 0 1 1 1 1 4Fe-4S dicluster domain TPP_enzyme_C PF02775.21 CBK20363.2 - 2.5e-07 30.6 0.1 5.8e-07 29.4 0.1 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Fer4_16 PF13484.6 CBK20363.2 - 2.8e-07 31.3 10.5 2e-05 25.4 11.7 2.7 1 1 1 2 2 2 2 4Fe-4S double cluster binding domain NAD_binding_1 PF00175.21 CBK20363.2 - 3.2e-07 31.0 0.0 1.1e-06 29.2 0.0 2.0 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Fer4_9 PF13187.6 CBK20363.2 - 5.5e-07 29.7 11.4 0.0026 17.9 1.6 2.8 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4 PF00037.27 CBK20363.2 - 2.4e-06 27.1 23.7 0.00023 20.8 5.5 3.5 3 0 0 3 3 3 2 4Fe-4S binding domain Fer4_10 PF13237.6 CBK20363.2 - 1.4e-05 25.1 8.9 1.4e-05 25.1 8.9 2.3 3 0 0 3 3 1 1 4Fe-4S dicluster domain Fer4_21 PF14697.6 CBK20363.2 - 0.00024 21.2 14.8 0.0024 18.0 14.8 2.6 1 1 0 1 1 1 1 4Fe-4S dicluster domain Transketolase_C PF02780.20 CBK20363.2 - 0.00041 20.2 0.6 0.0018 18.1 0.1 2.3 2 0 0 2 2 2 1 Transketolase, C-terminal domain Fer4_6 PF12837.7 CBK20363.2 - 0.00052 20.0 6.7 0.00052 20.0 6.7 3.6 3 0 0 3 3 3 2 4Fe-4S binding domain Fer4_17 PF13534.6 CBK20363.2 - 0.00083 19.8 11.5 0.019 15.5 2.0 3.5 3 0 0 3 3 2 2 4Fe-4S dicluster domain Fer4_2 PF12797.7 CBK20363.2 - 0.0075 16.3 18.5 0.017 15.2 2.7 3.5 3 0 0 3 3 3 2 4Fe-4S binding domain Fer4_18 PF13746.6 CBK20363.2 - 0.035 14.3 5.7 1.5 9.1 0.8 3.0 3 0 0 3 3 2 0 4Fe-4S dicluster domain Fer4_8 PF13183.6 CBK20363.2 - 0.04 14.3 13.3 0.23 11.9 13.1 2.5 1 1 2 3 3 3 0 4Fe-4S dicluster domain Fer4_15 PF13459.6 CBK20363.2 - 0.79 10.5 7.6 10 6.9 0.3 3.0 2 0 0 2 2 2 0 4Fe-4S single cluster domain Fer4_22 PF17179.4 CBK20363.2 - 4.3 8.3 9.0 5 8.0 2.2 3.0 2 0 0 2 2 2 0 4Fe-4S dicluster domain GTP_EFTU PF00009.27 CBK20364.2 - 2.4e-54 183.8 0.0 3.6e-54 183.3 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 CBK20364.2 - 3.2e-40 136.9 0.0 7.9e-40 135.7 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 CBK20364.2 - 9.5e-08 32.3 0.0 2.7e-07 30.9 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 CBK20364.2 - 0.00011 22.3 0.1 0.0022 18.1 0.1 2.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase Glyco_hydro_35 PF01301.19 CBK20365.2 - 5.3e-98 328.5 1.4 6.8e-98 328.2 1.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 Glyco_hydro_42 PF02449.15 CBK20365.2 - 3.3e-11 43.2 0.2 7.7e-11 41.9 0.1 1.7 2 0 0 2 2 2 1 Beta-galactosidase ArfGap PF01412.18 CBK20366.2 - 3.3e-34 117.5 0.7 6.8e-34 116.5 0.7 1.5 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf RGS PF00615.19 CBK20366.2 - 0.062 13.6 0.0 0.13 12.6 0.0 1.5 1 0 0 1 1 1 0 Regulator of G protein signaling domain RRM_1 PF00076.22 CBK20367.2 - 6.9e-12 45.0 0.0 1.3e-11 44.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PI3K_1B_p101 PF10486.9 CBK20367.2 - 1.9 6.1 20.2 2.5 5.8 20.2 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit DUF2723 PF11028.8 CBK20368.2 - 5.4e-13 49.2 4.6 1.5e-12 47.8 4.6 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF2723) Actin PF00022.19 CBK20369.2 - 3.5e-138 460.6 0.0 9.1e-138 459.3 0.0 1.6 1 1 0 1 1 1 1 Actin AAA PF00004.29 CBK20369.2 - 1.7e-41 141.7 0.0 4.7e-41 140.3 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CBK20369.2 - 5.1e-11 42.2 0.3 1.1e-10 41.1 0.3 1.5 1 0 0 1 1 1 1 AAA+ lid domain AAA_2 PF07724.14 CBK20369.2 - 8.6e-06 26.0 0.0 1.8e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) IstB_IS21 PF01695.17 CBK20369.2 - 2.3e-05 24.2 0.0 4.4e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_16 PF13191.6 CBK20369.2 - 0.00027 21.4 0.1 0.001 19.5 0.1 1.9 1 1 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.14 CBK20369.2 - 0.00058 19.9 0.1 0.0061 16.6 0.1 2.6 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 CBK20369.2 - 0.0081 16.4 0.5 0.42 10.9 0.5 2.9 2 1 0 2 2 2 1 AAA domain AAA_33 PF13671.6 CBK20369.2 - 0.0088 16.2 0.0 0.029 14.5 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 CBK20369.2 - 0.012 15.2 0.0 0.023 14.2 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_18 PF13238.6 CBK20369.2 - 0.017 15.7 0.0 0.056 14.0 0.0 1.9 2 0 0 2 2 1 0 AAA domain Sigma54_activ_2 PF14532.6 CBK20369.2 - 0.021 14.9 0.0 0.053 13.6 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain TIP49 PF06068.13 CBK20369.2 - 0.032 13.4 0.0 0.053 12.7 0.0 1.2 1 0 0 1 1 1 0 TIP49 P-loop domain Mg_chelatase PF01078.21 CBK20369.2 - 0.046 13.1 0.0 0.091 12.1 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.22 CBK20369.2 - 0.15 12.5 0.0 0.39 11.1 0.0 1.7 1 0 0 1 1 1 0 RNA helicase ABC_tran PF00005.27 CBK20369.2 - 0.17 12.4 0.0 0.42 11.1 0.0 1.6 1 0 0 1 1 1 0 ABC transporter AAA_30 PF13604.6 CBK20369.2 - 0.19 11.4 0.0 0.33 10.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain ANAPC4_WD40 PF12894.7 CBK20370.2 - 1.5e-05 25.2 0.0 0.076 13.3 0.0 3.7 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 CBK20370.2 - 0.15 13.0 0.1 4.8 8.2 0.0 3.3 4 0 0 4 4 4 0 WD domain, G-beta repeat MFS_1 PF07690.16 CBK20371.2 - 7.7e-27 94.1 41.0 2.4e-26 92.5 32.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MORN PF02493.20 CBK20372.2 - 0.0015 18.3 18.5 0.063 13.2 0.0 5.3 5 0 0 5 5 5 2 MORN repeat Orn_Arg_deC_N PF02784.16 CBK20373.2 - 4.5e-53 180.2 0.0 1.6e-52 178.4 0.0 1.7 2 0 0 2 2 2 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.22 CBK20373.2 - 1.3e-08 34.9 0.0 1.7e-08 34.6 0.0 1.4 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain Ala_racemase_N PF01168.20 CBK20373.2 - 0.00057 19.6 0.0 0.001 18.8 0.0 1.3 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain Ins134_P3_kin_N PF17927.1 CBK20373.2 - 0.12 12.8 0.1 0.37 11.2 0.0 1.9 1 1 0 1 1 1 0 Inositol 1,3,4-trisphosphate 5/6-kinase pre-ATP-grasp domain Pkinase PF00069.25 CBK20374.2 - 3.4e-31 108.6 1.4 5.1e-27 94.9 0.8 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CBK20374.2 - 2.2e-18 66.5 0.1 4.5e-18 65.5 0.1 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CBK20374.2 - 0.018 13.8 4.6 0.023 13.5 0.2 2.1 2 0 0 2 2 2 0 Fungal protein kinase Kdo PF06293.14 CBK20374.2 - 0.024 14.0 0.2 0.05 12.9 0.2 1.5 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CBK20374.2 - 0.037 13.9 0.1 3.6 7.4 0.1 2.2 2 0 0 2 2 2 0 Phosphotransferase enzyme family CCSAP PF15748.5 CBK20374.2 - 1.7 8.8 8.5 2.6 8.2 8.5 1.2 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated MCM PF00493.23 CBK20375.2 - 2.6e-86 288.4 0.0 4.1e-86 287.7 0.0 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 CBK20375.2 - 3.2e-25 88.4 0.6 6.2e-25 87.5 0.6 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 CBK20375.2 - 4.7e-24 84.6 0.4 8.7e-24 83.8 0.4 1.5 1 0 0 1 1 1 1 MCM AAA-lid domain AAA_5 PF07728.14 CBK20375.2 - 1.4e-07 31.6 0.0 4.5e-07 29.9 0.0 2.0 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 CBK20375.2 - 4.4e-07 29.5 0.3 0.0023 17.4 0.0 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.26 CBK20375.2 - 0.00052 19.8 0.1 0.0018 18.0 0.1 1.9 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_3 PF07726.11 CBK20375.2 - 0.0056 16.5 0.1 0.058 13.3 0.0 2.6 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 CBK20375.2 - 0.036 13.8 0.2 0.19 11.5 0.0 2.2 2 1 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 CBK20375.2 - 0.048 14.0 0.0 0.24 11.8 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain TrwB_AAD_bind PF10412.9 CBK20375.2 - 0.057 12.3 0.0 0.15 11.0 0.0 1.6 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain DUF1940 PF09155.10 CBK20375.2 - 0.066 13.3 0.5 0.12 12.4 0.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1940) AAA_lid_2 PF17863.1 CBK20375.2 - 0.12 12.3 0.1 0.39 10.6 0.1 1.8 1 0 0 1 1 1 0 AAA lid domain AAA PF00004.29 CBK20375.2 - 0.16 12.4 0.3 0.79 10.2 0.1 2.2 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Cadherin PF00028.17 CBK20376.2 - 1.7e-80 265.5 17.4 6.1e-11 42.6 0.5 14.2 14 0 0 14 14 14 12 Cadherin domain TIG PF01833.24 CBK20376.2 - 1.2e-50 169.5 64.2 5.6e-11 42.4 0.9 14.2 13 0 0 13 13 13 10 IPT/TIG domain Cadherin_4 PF17803.1 CBK20376.2 - 1.8e-10 41.3 31.5 0.0086 16.7 0.1 10.9 11 0 0 11 11 11 5 Bacterial cadherin-like domain Big_9 PF17963.1 CBK20376.2 - 1.1e-07 32.4 34.3 0.034 14.9 0.1 11.2 12 0 0 12 12 12 2 Bacterial Ig domain UPF0242 PF06785.11 CBK20376.2 - 0.011 15.8 0.8 0.042 14.0 0.8 1.9 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Ephrin_rec_like PF07699.13 CBK20376.2 - 1.6 8.5 7.1 2.2 8.1 0.6 2.9 2 0 0 2 2 2 0 Putative ephrin-receptor like Cadherin PF00028.17 CBK20377.2 - 8.9e-09 35.7 0.2 2.7e-05 24.5 0.0 2.9 2 1 0 2 2 2 2 Cadherin domain EpmC PF04315.12 CBK20378.2 - 6.6e-22 77.9 6.2 46 3.7 0.0 26.3 31 0 0 31 31 31 2 Elongation factor P hydroxylase ApeC PF16977.5 CBK20378.2 - 1.9e-05 24.7 318.8 0.38 10.6 1.7 39.4 8 8 6 39 39 39 36 C-terminal domain of apextrin SUB1_ProdP9 PF18213.1 CBK20379.2 - 0.071 13.0 0.1 0.14 12.0 0.1 1.5 1 0 0 1 1 1 0 SUB1 protease Prodomain ProdP9 Roc PF08477.13 CBK20380.2 - 5.5e-05 23.4 0.1 0.0011 19.1 0.0 2.3 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase SNARE PF05739.19 CBK20382.2 - 2.2e-11 43.6 1.5 3.3e-11 43.0 1.5 1.3 1 0 0 1 1 1 1 SNARE domain Prominin PF05478.11 CBK20382.2 - 0.012 13.6 1.2 0.014 13.4 1.2 1.0 1 0 0 1 1 1 0 Prominin PgaD PF13994.6 CBK20382.2 - 0.021 14.9 0.0 0.021 14.9 0.0 1.2 1 0 0 1 1 1 0 PgaD-like protein Histone_HNS PF00816.21 CBK20382.2 - 0.023 15.5 0.3 0.029 15.2 0.3 1.1 1 0 0 1 1 1 0 H-NS histone family Synaptobrevin PF00957.21 CBK20382.2 - 0.041 13.7 3.3 0.052 13.4 3.3 1.2 1 0 0 1 1 1 0 Synaptobrevin RIFIN PF02009.16 CBK20382.2 - 0.079 12.8 3.2 0.083 12.8 3.2 1.0 1 0 0 1 1 1 0 Rifin Neurensin PF14927.6 CBK20382.2 - 0.089 12.5 0.2 0.1 12.3 0.2 1.1 1 0 0 1 1 1 0 Neurensin DUF4668 PF15701.5 CBK20382.2 - 0.093 12.6 0.2 0.12 12.3 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4668) DUF4366 PF14283.6 CBK20382.2 - 0.095 12.7 0.7 0.16 12.0 0.7 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4366) DUF5345 PF17280.2 CBK20382.2 - 0.11 12.5 1.6 0.23 11.4 1.4 1.6 1 1 1 2 2 2 0 Family of unknown function (DUF5345) Epiglycanin_C PF14654.6 CBK20382.2 - 0.14 12.2 0.2 0.17 12.0 0.2 1.2 1 0 0 1 1 1 0 Mucin, catalytic, TM and cytoplasmic tail region MPS-4 PF17523.2 CBK20382.2 - 0.3 11.2 1.9 0.37 10.9 1.9 1.3 1 1 0 1 1 1 0 MinK-related peptide, potassium channel accessory sub-unit protein 4 FeoB_associated PF12669.7 CBK20382.2 - 3.2 8.2 6.7 0.3 11.5 2.2 1.6 2 0 0 2 2 2 0 FeoB-associated Cys-rich membrane protein NapE PF06796.11 CBK20382.2 - 4.2 7.0 6.3 11 5.7 6.3 1.7 1 1 0 1 1 1 0 Periplasmic nitrate reductase protein NapE Trypan_PARP PF05887.11 CBK20384.2 - 0.0023 17.9 8.5 0.0032 17.4 8.5 1.2 1 0 0 1 1 1 1 Procyclic acidic repetitive protein (PARP) LRR_8 PF13855.6 CBK20384.2 - 0.0033 17.2 3.7 0.22 11.3 0.0 3.2 2 1 1 3 3 3 2 Leucine rich repeat SpoU_methylase PF00588.19 CBK20387.2 - 2.8e-25 89.1 0.0 4.8e-25 88.4 0.0 1.4 1 0 0 1 1 1 1 SpoU rRNA Methylase family zf-C2H2 PF00096.26 CBK20388.2 - 2.4e-18 65.5 52.5 0.00013 22.2 0.3 8.1 7 1 1 8 8 8 6 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CBK20388.2 - 2.8e-14 52.6 51.8 0.017 15.9 2.9 8.2 7 1 1 8 8 8 6 C2H2-type zinc finger zf-H2C2_2 PF13465.6 CBK20388.2 - 2.9e-11 43.2 44.7 0.0023 18.3 0.7 7.5 8 0 0 8 8 8 4 Zinc-finger double domain zf-C2H2_8 PF15909.5 CBK20388.2 - 9.3e-05 22.7 22.3 0.049 13.9 7.6 3.9 1 1 3 4 4 4 3 C2H2-type zinc ribbon FOXP-CC PF16159.5 CBK20388.2 - 0.00011 22.8 22.3 0.028 15.0 0.1 5.9 4 1 2 6 6 6 3 FOXP coiled-coil domain zf-C2H2_aberr PF17017.5 CBK20388.2 - 0.0035 17.5 17.3 0.11 12.6 2.5 4.9 1 1 3 5 5 5 3 Aberrant zinc-finger zf-met PF12874.7 CBK20388.2 - 0.033 14.6 37.1 0.2 12.1 2.0 8.1 8 0 0 8 8 8 0 Zinc-finger of C2H2 type zf-met2 PF12907.7 CBK20388.2 - 0.1 12.7 0.0 0.1 12.7 0.0 4.1 4 0 0 4 4 4 0 Zinc-binding ALAD PF00490.21 CBK20388.2 - 0.64 9.1 2.1 1.2 8.2 1.2 1.8 2 0 0 2 2 2 0 Delta-aminolevulinic acid dehydratase zinc_ribbon_15 PF17032.5 CBK20388.2 - 2.9 8.7 21.0 0.82 10.5 1.8 4.1 2 1 1 3 3 3 0 zinc-ribbon family DUF3510 PF12022.8 CBK20389.2 - 4.7e-10 39.9 0.3 7.6e-10 39.3 0.3 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3510) DUF5062 PF16691.5 CBK20389.2 - 0.087 13.0 0.1 0.14 12.3 0.1 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF5062) Ribosomal_L6e PF01159.19 CBK20390.2 - 5.8e-23 81.5 0.2 3.3e-22 79.1 0.2 1.9 1 1 0 1 1 1 1 Ribosomal protein L6e Myb_DNA-binding PF00249.31 CBK20391.2 - 1.6e-43 146.6 19.9 6.8e-13 48.6 1.3 5.7 5 1 0 5 5 5 5 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 CBK20391.2 - 1.3e-38 131.1 11.6 2.1e-13 50.3 0.6 5.6 1 1 4 5 5 5 5 Myb-like DNA-binding domain SLIDE PF09111.10 CBK20391.2 - 1.5e-06 28.2 9.1 0.011 15.7 0.1 4.7 3 1 2 5 5 5 3 SLIDE Myb_DNA-bind_2 PF08914.11 CBK20391.2 - 0.0012 19.0 3.1 0.52 10.5 0.8 4.0 3 1 0 3 3 3 1 Rap1 Myb domain Rap1_C PF11626.8 CBK20391.2 - 0.0059 16.7 0.7 0.5 10.5 0.0 3.6 3 1 1 4 4 4 1 TRF2-interacting telomeric protein/Rap1 - C terminal domain AbiJ_NTD5 PF18865.1 CBK20391.2 - 0.011 15.5 0.0 0.14 12.0 0.0 2.7 3 0 0 3 3 3 0 AbiJ N-terminal domain 5 Myb_DNA-bind_4 PF13837.6 CBK20391.2 - 0.062 13.7 15.2 1.1 9.6 0.1 4.8 5 0 0 5 5 5 0 Myb/SANT-like DNA-binding domain Cas6b_C PF17262.2 CBK20391.2 - 0.098 12.8 0.3 0.53 10.4 0.6 2.0 2 0 0 2 2 2 0 Cas6b C-terminal domain Rsd_AlgQ PF04353.13 CBK20392.2 - 0.016 15.2 0.0 0.019 14.9 0.0 1.2 1 0 0 1 1 1 0 Regulator of RNA polymerase sigma(70) subunit, Rsd/AlgQ DUF2157 PF09925.9 CBK20392.2 - 0.026 14.3 0.0 0.037 13.8 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2157) HSBP1 PF06825.12 CBK20392.2 - 0.036 13.9 0.8 0.063 13.1 0.3 1.6 2 0 0 2 2 2 0 Heat shock factor binding protein 1 CYSTM PF12734.7 CBK20392.2 - 0.044 14.1 0.0 0.071 13.4 0.0 1.3 1 0 0 1 1 1 0 Cysteine-rich TM module stress tolerance Fcf1 PF04900.12 CBK20393.2 - 1.2e-37 128.3 1.7 1.2e-37 128.3 1.7 1.8 2 0 0 2 2 2 1 Fcf1 PIN_9 PF18477.1 CBK20393.2 - 1.2e-12 48.1 0.5 2.5e-12 47.1 0.0 1.7 2 0 0 2 2 2 1 PIN like domain WHIM1 PF15612.6 CBK20393.2 - 0.027 14.0 0.0 0.054 13.1 0.0 1.5 1 0 0 1 1 1 0 WSTF, HB1, Itc1p, MBD9 motif 1 Cpn60_TCP1 PF00118.24 CBK20394.2 - 4.3e-164 546.8 0.3 4.9e-164 546.6 0.3 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family PHO4 PF01384.20 CBK20396.2 - 3.6e-105 351.8 23.3 1.8e-67 227.8 8.9 2.8 1 1 1 2 2 2 2 Phosphate transporter family Shisa PF13908.6 CBK20396.2 - 0.025 14.8 0.0 0.048 13.9 0.0 1.4 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator LapA_dom PF06305.11 CBK20396.2 - 0.053 13.3 0.0 0.053 13.3 0.0 4.9 5 1 0 5 5 5 0 Lipopolysaccharide assembly protein A domain tRNA-synt_1g PF09334.11 CBK20397.2 - 1.4e-147 491.6 0.0 1.8e-147 491.2 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 CBK20397.2 - 5e-09 35.0 0.5 0.00029 19.3 0.0 3.1 2 1 1 3 3 3 2 tRNA synthetases class I (I, L, M and V) DZR PF12773.7 CBK20397.2 - 0.053 13.6 6.0 0.28 11.2 6.0 2.4 1 1 0 1 1 1 0 Double zinc ribbon GST_C_2 PF13410.6 CBK20397.2 - 0.31 11.1 2.4 0.38 10.8 0.1 2.3 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain zinc_ribbon_9 PF14369.6 CBK20397.2 - 1.1 9.6 4.9 0.3 11.4 1.1 2.1 2 0 0 2 2 2 0 zinc-ribbon RecR PF02132.15 CBK20397.2 - 3.9 7.1 5.0 7.1 6.3 0.6 2.7 2 0 0 2 2 2 0 RecR protein Cnd3 PF12719.7 CBK20398.2 - 9.4e-19 67.7 5.2 1.5e-17 63.7 1.5 2.6 2 0 0 2 2 2 2 Nuclear condensing complex subunits, C-term domain HEAT PF02985.22 CBK20398.2 - 0.00068 19.7 1.3 8.5 6.9 0.0 4.6 4 0 0 4 4 4 2 HEAT repeat LRR_8 PF13855.6 CBK20399.2 - 0.015 15.1 0.7 0.12 12.2 0.2 2.3 2 1 0 2 2 2 0 Leucine rich repeat Sialidase PF02973.16 CBK20399.2 - 0.031 13.8 0.3 0.21 11.1 0.0 2.1 1 1 0 2 2 2 0 Sialidase, N-terminal domain hSac2 PF12456.8 CBK20399.2 - 0.055 13.2 0.5 7 6.4 0.0 3.1 1 1 3 4 4 4 0 Inositol phosphatase DnaJ PF00226.31 CBK20402.2 - 4.3e-14 52.4 0.1 1.9e-13 50.3 0.1 2.1 2 0 0 2 2 2 1 DnaJ domain TPR_8 PF13181.6 CBK20402.2 - 1.5e-12 46.6 0.8 0.071 13.4 0.0 6.5 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_1 PF00515.28 CBK20402.2 - 9.2e-10 37.9 0.6 0.049 13.5 0.0 4.5 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_9 PF13371.6 CBK20402.2 - 5.8e-08 32.8 0.0 6.1e-05 23.1 0.0 3.3 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 CBK20402.2 - 1e-07 31.5 0.0 2.3 8.5 0.0 6.2 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_19 PF14559.6 CBK20402.2 - 9.4e-06 26.1 0.0 0.053 14.0 0.0 3.2 2 1 2 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 CBK20402.2 - 7.9e-05 22.9 0.0 0.027 14.7 0.0 3.9 2 2 2 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.6 CBK20402.2 - 0.00035 21.1 0.0 11 7.1 0.0 4.6 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_15 PF13429.6 CBK20402.2 - 0.012 14.9 0.0 3.1 6.9 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.6 CBK20402.2 - 0.013 16.1 0.4 0.89 10.3 0.0 4.1 5 0 0 5 5 4 0 Tetratricopeptide repeat ANAPC3 PF12895.7 CBK20402.2 - 0.02 15.1 0.1 8.1 6.8 0.1 3.5 3 1 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.6 CBK20402.2 - 0.056 13.8 0.1 1.2e+02 3.5 0.1 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat RPN7 PF10602.9 CBK20402.2 - 0.12 12.1 0.4 7.1 6.3 0.2 3.1 2 1 1 3 3 3 0 26S proteasome subunit RPN7 Ribophorin_I PF04597.14 CBK20403.2 - 5e-122 408.3 3.4 5.7e-122 408.1 3.4 1.0 1 0 0 1 1 1 1 Ribophorin I DEAD PF00270.29 CBK20404.2 - 5e-16 59.0 0.0 7e-16 58.5 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 CBK20404.2 - 1.9e-05 24.8 0.0 3.8e-05 23.7 0.0 1.4 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 CBK20404.2 - 0.0025 18.1 0.1 0.023 14.9 0.1 2.4 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 CBK20404.2 - 0.18 11.5 0.0 13 5.5 0.0 2.2 2 0 0 2 2 2 0 AAA domain Ribosomal_L14 PF00238.19 CBK20405.2 - 1.3e-35 122.1 0.0 1.5e-35 121.9 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e tRNA-synt_1 PF00133.22 CBK20407.2 - 2.2e-33 115.4 0.0 1.9e-21 76.0 0.0 2.9 2 1 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.11 CBK20407.2 - 1.5e-20 73.3 1.0 1.8e-10 40.1 0.0 3.3 3 0 0 3 3 3 2 tRNA synthetases class I (M) Anticodon_1 PF08264.13 CBK20407.2 - 2.1e-10 40.8 0.1 7.1e-10 39.0 0.0 1.9 1 1 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.19 CBK20407.2 - 6.8e-10 38.8 0.0 1.6e-09 37.5 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1f PF01921.18 CBK20407.2 - 0.063 12.2 0.0 0.11 11.3 0.0 1.3 1 0 0 1 1 1 0 tRNA synthetases class I (K) CIA30 PF08547.12 CBK20408.2 - 2.3e-19 70.0 0.0 2.7e-19 69.7 0.0 1.0 1 0 0 1 1 1 1 Complex I intermediate-associated protein 30 (CIA30) Med6 PF04934.14 CBK20409.2 - 8.3e-16 58.0 2.7 3.2e-10 39.9 0.2 2.5 1 1 1 2 2 2 2 MED6 mediator sub complex component DUF4795 PF16043.5 CBK20410.2 - 0.059 13.0 2.3 0.096 12.3 2.3 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) GHL5 PF14872.6 CBK20411.2 - 0.071 11.1 0.3 0.074 11.1 0.3 1.0 1 0 0 1 1 1 0 Hypothetical glycoside hydrolase 5 Tom22 PF04281.13 CBK20413.2 - 6.1e-08 32.5 0.3 5.9e-07 29.4 0.0 1.9 1 1 1 2 2 2 1 Mitochondrial import receptor subunit Tom22 DUF4710 PF15828.5 CBK20413.2 - 0.066 13.3 1.1 0.071 13.2 0.2 1.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4710) Pkinase PF00069.25 CBK20414.2 - 5.5e-60 203.0 0.0 6.7e-60 202.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBK20414.2 - 8.9e-33 113.7 0.0 1.5e-32 112.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CBK20414.2 - 9.4e-10 38.3 0.0 1.3e-09 37.9 0.0 1.1 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 CBK20414.2 - 0.015 15.2 0.0 0.54 10.1 0.0 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 CBK20414.2 - 0.25 10.1 0.0 0.36 9.6 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase EF-hand_7 PF13499.6 CBK20415.2 - 2.5e-09 37.5 13.3 0.00013 22.3 3.8 3.0 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 CBK20415.2 - 8.3e-09 34.6 4.1 0.0025 17.3 0.2 3.3 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.6 CBK20415.2 - 2.9e-08 33.0 10.1 0.00012 21.7 0.8 3.4 4 0 0 4 4 4 2 EF-hand domain EF-hand_1 PF00036.32 CBK20415.2 - 4e-08 32.2 12.1 0.0001 21.6 1.1 3.8 5 0 0 5 5 5 2 EF hand EF-hand_8 PF13833.6 CBK20415.2 - 7.2e-08 32.2 5.8 0.037 13.9 0.4 4.4 3 1 1 4 4 4 3 EF-hand domain pair EF-hand_9 PF14658.6 CBK20415.2 - 3.5e-05 24.0 0.0 0.0032 17.8 0.0 2.2 2 0 0 2 2 2 1 EF-hand domain SPARC_Ca_bdg PF10591.9 CBK20415.2 - 0.00035 20.9 1.4 0.56 10.5 0.1 2.5 2 2 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region Gp_dh_C PF02800.20 CBK20416.2 - 1.2e-28 99.7 0.0 1.8e-28 99.1 0.0 1.2 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 CBK20416.2 - 1.5e-25 89.5 0.0 2.7e-25 88.6 0.0 1.4 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DapB_N PF01113.20 CBK20416.2 - 0.019 15.1 0.0 0.098 12.8 0.0 2.0 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus ADH_zinc_N PF00107.26 CBK20416.2 - 0.075 13.0 0.0 0.19 11.7 0.0 1.8 2 0 0 2 2 2 0 Zinc-binding dehydrogenase F420_oxidored PF03807.17 CBK20416.2 - 0.08 13.5 0.0 7.2 7.3 0.0 2.3 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent COPI_assoc PF08507.10 CBK20417.2 - 7.7e-15 55.1 10.1 1e-14 54.7 10.1 1.1 1 0 0 1 1 1 1 COPI associated protein DUF2207 PF09972.9 CBK20417.2 - 0.00088 18.2 1.3 0.00088 18.2 1.3 2.2 1 1 1 2 2 2 1 Predicted membrane protein (DUF2207) PRA1 PF03208.19 CBK20417.2 - 0.0037 16.9 4.0 0.0087 15.7 3.6 1.9 1 1 0 1 1 1 1 PRA1 family protein DUF2304 PF10066.9 CBK20417.2 - 0.022 15.0 1.9 0.022 15.0 1.9 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2304) Claudin_2 PF13903.6 CBK20417.2 - 0.58 9.9 6.4 0.064 13.0 0.5 2.0 1 1 1 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction Promethin PF16015.5 CBK20417.2 - 3.1 7.8 9.9 0.61 10.0 1.2 2.9 3 0 0 3 3 3 0 Promethin MBOAT PF03062.19 CBK20418.2 - 1.1e-26 94.0 19.5 1.5e-26 93.6 19.5 1.1 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.6 CBK20418.2 - 1.8e-05 24.9 2.8 1.8e-05 24.9 2.8 2.0 2 0 0 2 2 2 1 Membrane bound O-acyl transferase family GWT1 PF06423.12 CBK20418.2 - 1.9 8.6 7.5 0.25 11.4 2.8 1.8 2 0 0 2 2 2 0 GWT1 Na_Ca_ex PF01699.24 CBK20420.2 - 3.7e-13 49.7 11.6 5e-13 49.3 11.6 1.2 1 0 0 1 1 1 1 Sodium/calcium exchanger protein EF-hand_7 PF13499.6 CBK20420.2 - 1.4e-12 47.9 1.2 3.2e-12 46.7 1.2 1.7 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 CBK20420.2 - 2.4e-09 36.1 1.2 0.00051 19.4 0.2 2.8 2 1 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 CBK20420.2 - 5.2e-09 35.3 2.9 0.00046 19.9 0.1 3.0 2 1 1 3 3 3 2 EF-hand domain EF-hand_8 PF13833.6 CBK20420.2 - 4.5e-08 32.8 0.3 1.4e-07 31.2 0.3 1.9 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.6 CBK20420.2 - 0.0035 16.8 0.2 0.37 10.4 0.0 2.4 2 0 0 2 2 2 1 EF hand SAP PF02037.27 CBK20420.2 - 0.016 14.9 0.1 0.72 9.7 0.0 2.6 2 0 0 2 2 2 0 SAP domain SPARC_Ca_bdg PF10591.9 CBK20420.2 - 0.053 13.8 0.1 0.094 13.0 0.1 1.5 1 0 0 1 1 1 0 Secreted protein acidic and rich in cysteine Ca binding region RRP7 PF12923.7 CBK20421.2 - 7e-08 32.6 0.6 1.2e-07 31.9 0.6 1.4 1 0 0 1 1 1 1 Ribosomal RNA-processing protein 7 (RRP7) C-terminal domain RRM_1 PF00076.22 CBK20421.2 - 0.0015 18.3 0.1 0.025 14.4 0.0 2.3 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_Rrp7 PF17799.1 CBK20421.2 - 0.13 12.0 0.0 0.3 10.9 0.0 1.5 1 1 0 1 1 1 0 Rrp7 RRM-like N-terminal domain BRCT PF00533.26 CBK20422.2 - 2.9e-09 37.2 0.0 4.5e-09 36.6 0.0 1.3 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 CBK20422.2 - 0.00044 20.2 0.1 0.00065 19.6 0.1 1.3 1 0 0 1 1 1 1 twin BRCT domain SSPI PF14098.6 CBK20422.2 - 0.1 12.8 3.2 0.21 11.7 2.8 1.8 2 0 0 2 2 2 0 Small, acid-soluble spore protein I GILT PF03227.16 CBK20423.2 - 4.4e-26 91.2 1.7 7.2e-26 90.5 1.7 1.3 1 0 0 1 1 1 1 Gamma interferon inducible lysosomal thiol reductase (GILT) DUF1604 PF07713.13 CBK20424.2 - 2e-27 94.8 0.7 2e-27 94.8 0.7 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF1604) Stealth_CR2 PF11380.8 CBK20426.2 - 2.5e-44 149.9 1.6 8.6e-44 148.1 0.4 2.1 2 0 0 2 2 2 1 Stealth protein CR2, conserved region 2 Stealth_CR1 PF17101.5 CBK20426.2 - 4.8e-13 48.6 0.3 1.2e-12 47.3 0.3 1.7 1 0 0 1 1 1 1 Stealth protein CR1, conserved region 1 Notch PF00066.17 CBK20426.2 - 1.4e-12 47.8 32.2 2.5e-07 31.0 11.2 2.4 2 0 0 2 2 2 2 LNR domain DUF167 PF02594.16 CBK20427.2 - 4.6e-22 77.9 0.1 6.5e-22 77.5 0.1 1.2 1 0 0 1 1 1 1 Uncharacterised ACR, YggU family COG1872 Msap1 PF17077.5 CBK20427.2 - 0.11 11.7 0.1 0.14 11.3 0.1 1.1 1 0 0 1 1 1 0 Mitotic spindle associated protein SHE1 Exo_endo_phos PF03372.23 CBK20428.2 - 5.8e-19 68.5 0.0 1.1e-18 67.7 0.0 1.4 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Cullin PF00888.22 CBK20429.2 - 1e-07 31.0 2.4 1.2e-07 30.8 2.4 1.2 1 0 0 1 1 1 1 Cullin family Suppressor_P21 PF11479.8 CBK20429.2 - 0.087 13.0 2.3 0.26 11.5 0.4 2.9 1 1 1 2 2 2 0 RNA silencing suppressor P21 C-terminal domain Cullin PF00888.22 CBK20430.2 - 6.9e-10 38.2 0.4 1.1e-09 37.6 0.0 1.4 2 0 0 2 2 2 1 Cullin family Cullin_Nedd8 PF10557.9 CBK20430.2 - 4e-08 33.2 2.0 5.3e-08 32.8 0.8 1.8 2 0 0 2 2 2 1 Cullin protein neddylation domain FolB PF02152.18 CBK20430.2 - 0.023 15.2 0.3 0.042 14.4 0.3 1.4 1 0 0 1 1 1 0 Dihydroneopterin aldolase Oxidored_q4 PF00507.19 CBK20431.2 - 0.51 10.5 10.5 7.7 6.8 6.0 2.4 1 1 1 2 2 2 0 NADH-ubiquinone/plastoquinone oxidoreductase, chain 3 GILT PF03227.16 CBK20432.2 - 2.2e-20 72.9 0.8 4.4e-20 71.9 0.8 1.5 1 1 1 2 2 2 1 Gamma interferon inducible lysosomal thiol reductase (GILT) ubiquitin PF00240.23 CBK20433.2 - 4.2e-35 119.3 0.5 4.6e-35 119.2 0.5 1.0 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 CBK20433.2 - 1.2e-16 60.3 0.6 1.3e-16 60.1 0.6 1.0 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 CBK20433.2 - 3.2e-06 27.5 0.1 1.3e-05 25.6 0.1 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain Ubiquitin_4 PF18036.1 CBK20433.2 - 0.0012 18.9 0.3 1.2 9.3 0.1 2.0 2 0 0 2 2 2 2 Ubiquitin-like domain TBK1_ULD PF18396.1 CBK20433.2 - 0.0015 18.4 0.0 0.0017 18.2 0.0 1.2 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain Ubiquitin_5 PF18037.1 CBK20433.2 - 0.0021 18.4 0.1 0.0024 18.2 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 CBK20433.2 - 0.003 17.7 0.1 0.0062 16.6 0.1 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 CBK20433.2 - 0.0096 16.5 0.1 0.011 16.3 0.1 1.1 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain Sde2_N_Ubi PF13019.6 CBK20433.2 - 0.028 14.3 0.0 0.031 14.1 0.0 1.1 1 0 0 1 1 1 0 Silencing defective 2 N-terminal ubiquitin domain Fucokinase PF07959.12 CBK20434.2 - 4.1e-43 147.8 0.0 6.1e-43 147.3 0.0 1.2 1 0 0 1 1 1 1 L-fucokinase GHMP_kinases_C PF08544.13 CBK20434.2 - 7.4e-07 29.4 0.0 2e-06 28.0 0.0 1.7 1 0 0 1 1 1 1 GHMP kinases C terminal GHMP_kinases_N PF00288.26 CBK20434.2 - 4.1e-05 23.7 0.5 0.00012 22.2 0.5 1.8 1 0 0 1 1 1 1 GHMP kinases N terminal domain LSM PF01423.22 CBK20435.2 - 1.8e-16 59.6 0.2 2.1e-16 59.3 0.2 1.1 1 0 0 1 1 1 1 LSM domain Pkinase PF00069.25 CBK20436.2 - 5.5e-60 203.0 0.0 1.1e-59 202.0 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBK20436.2 - 1.5e-22 80.1 0.0 3.1e-22 79.1 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 CBK20436.2 - 0.0028 17.0 0.4 0.0052 16.2 0.4 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CBK20436.2 - 0.032 14.2 0.1 0.054 13.4 0.1 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family SBP_bac_3 PF00497.20 CBK20437.2 - 1.5e-07 31.1 0.0 0.0053 16.2 0.0 2.2 2 0 0 2 2 2 2 Bacterial extracellular solute-binding proteins, family 3 NIF PF03031.18 CBK20438.2 - 2.8e-50 170.1 0.1 3.5e-50 169.8 0.1 1.1 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase HAD PF12710.7 CBK20438.2 - 0.00052 20.5 0.0 0.0059 17.0 0.0 2.1 1 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cofilin_ADF PF00241.20 CBK20439.2 - 1.7e-26 92.4 0.3 1.9e-26 92.2 0.3 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein CHASE2 PF05226.11 CBK20439.2 - 0.041 13.6 0.0 0.041 13.6 0.0 1.1 1 0 0 1 1 1 0 CHASE2 domain PfkB PF00294.24 CBK20440.2 - 0.00027 20.4 0.0 0.0046 16.3 0.0 2.2 1 1 1 2 2 2 2 pfkB family carbohydrate kinase NDUF_B7 PF05676.13 CBK20441.2 - 8.2e-24 83.1 3.0 8.8e-24 83.0 3.0 1.0 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) Chordopox_G3 PF06129.12 CBK20442.2 - 0.025 15.3 0.2 0.026 15.2 0.2 1.1 1 0 0 1 1 1 0 Chordopoxvirus G3 protein Transket_pyr PF02779.24 CBK20444.2 - 6.1e-46 156.3 0.0 8.4e-46 155.9 0.0 1.2 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 CBK20444.2 - 5.3e-44 149.1 0.1 1.4e-43 147.7 0.0 1.7 2 0 0 2 2 2 1 Transketolase, C-terminal domain PFOR_II PF17147.4 CBK20444.2 - 0.0099 16.2 0.0 0.026 14.8 0.0 1.8 1 0 0 1 1 1 1 Pyruvate:ferredoxin oxidoreductase core domain II Na_H_Exchanger PF00999.21 CBK20445.2 - 6.1e-15 54.9 19.0 7.8e-15 54.5 19.0 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Trypan_PARP PF05887.11 CBK20447.2 - 0.0035 17.3 5.9 0.0051 16.8 5.9 1.2 1 0 0 1 1 1 1 Procyclic acidic repetitive protein (PARP) LRR_8 PF13855.6 CBK20447.2 - 0.64 9.8 4.4 3.9 7.3 0.3 2.9 2 1 1 3 3 3 0 Leucine rich repeat Beach PF02138.18 CBK20448.2 - 1.8e-85 286.7 0.0 2.2e-85 286.4 0.0 1.1 1 0 0 1 1 1 1 Beige/BEACH domain PH_BEACH PF14844.6 CBK20448.2 - 5.5e-12 45.7 0.0 1e-11 44.8 0.0 1.5 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH Ras PF00071.22 CBK20449.2 - 1e-65 220.3 1.1 1.2e-65 220.1 1.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CBK20449.2 - 2.8e-36 124.4 0.8 4e-36 123.9 0.1 1.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CBK20449.2 - 1.4e-17 63.7 0.3 1.8e-17 63.3 0.3 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 CBK20449.2 - 7.8e-07 28.7 0.2 9.3e-07 28.4 0.2 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 CBK20449.2 - 3.8e-06 26.9 0.6 0.047 13.6 0.2 2.2 1 1 1 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 CBK20449.2 - 0.00014 21.9 0.0 0.00039 20.5 0.0 1.7 1 1 1 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 CBK20449.2 - 0.00024 20.7 0.3 0.00051 19.6 0.3 1.5 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA PF00004.29 CBK20449.2 - 0.0018 18.7 0.1 0.098 13.1 0.0 2.2 1 1 1 2 2 2 1 ATPase family associated with various cellular activities (AAA) SRPRB PF09439.10 CBK20449.2 - 0.0022 17.4 0.1 0.0028 17.1 0.1 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit FeoB_N PF02421.18 CBK20449.2 - 0.0047 16.5 0.1 0.026 14.1 0.1 1.9 1 1 0 1 1 1 1 Ferrous iron transport protein B AAA_22 PF13401.6 CBK20449.2 - 0.024 14.9 0.0 0.09 13.1 0.0 2.2 1 1 0 1 1 1 0 AAA domain GbpA_2 PF18416.1 CBK20449.2 - 0.037 14.3 0.5 6.2 7.2 0.1 2.7 2 1 1 3 3 3 0 N-acetylglucosamine binding protein domain 2 AAA_16 PF13191.6 CBK20449.2 - 0.04 14.3 0.0 0.061 13.7 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain AAA_7 PF12775.7 CBK20449.2 - 0.047 13.2 0.0 0.48 9.9 0.0 2.0 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_29 PF13555.6 CBK20449.2 - 0.061 13.1 0.0 0.15 11.8 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain TniB PF05621.11 CBK20449.2 - 0.09 12.2 0.0 0.23 10.8 0.0 1.6 2 0 0 2 2 2 0 Bacterial TniB protein AAA_5 PF07728.14 CBK20449.2 - 0.15 12.0 0.1 0.29 11.2 0.1 1.7 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) UPRTase PF14681.6 CBK20450.2 - 3.6e-59 199.7 0.0 4.2e-59 199.5 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.27 CBK20450.2 - 3.4e-06 26.7 0.0 6.4e-06 25.8 0.0 1.6 2 0 0 2 2 2 1 Phosphoribosyl transferase domain Pkinase PF00069.25 CBK20451.2 - 8.7e-56 189.2 0.3 1e-55 189.0 0.3 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBK20451.2 - 1.3e-25 90.2 0.4 2.1e-25 89.5 0.4 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 CBK20451.2 - 0.00084 18.4 0.4 0.0012 17.8 0.4 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 CBK20451.2 - 0.0036 16.7 0.1 0.0079 15.6 0.0 1.6 2 0 0 2 2 2 1 Kinase-like RIO1 PF01163.22 CBK20451.2 - 0.007 16.0 0.3 0.012 15.2 0.3 1.3 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.14 CBK20451.2 - 0.062 12.6 0.2 0.12 11.7 0.2 1.5 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Cpn10 PF00166.21 CBK20452.2 - 3.1e-24 84.8 0.0 4.2e-24 84.4 0.0 1.1 1 0 0 1 1 1 1 Chaperonin 10 Kd subunit SoxG PF04268.12 CBK20452.2 - 0.14 12.3 0.0 0.2 11.8 0.0 1.2 1 0 0 1 1 1 0 Sarcosine oxidase, gamma subunit family MBF1 PF08523.10 CBK20453.2 - 1.3e-14 54.4 2.1 2.4e-14 53.6 2.1 1.5 1 0 0 1 1 1 1 Multiprotein bridging factor 1 HTH_3 PF01381.22 CBK20453.2 - 2.9e-13 49.6 0.2 4.4e-13 49.1 0.2 1.3 1 0 0 1 1 1 1 Helix-turn-helix HTH_31 PF13560.6 CBK20453.2 - 2.4e-07 31.0 0.0 5.2e-07 29.9 0.0 1.5 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_25 PF13413.6 CBK20453.2 - 0.00022 21.0 0.0 0.00038 20.3 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_19 PF12844.7 CBK20453.2 - 0.0013 18.7 0.1 0.0025 17.8 0.1 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_37 PF13744.6 CBK20453.2 - 0.018 15.0 0.2 0.048 13.6 0.1 1.7 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_26 PF13443.6 CBK20453.2 - 0.051 14.0 0.1 0.079 13.4 0.1 1.3 1 0 0 1 1 1 0 Cro/C1-type HTH DNA-binding domain HTH_38 PF13936.6 CBK20453.2 - 0.054 13.3 0.0 0.17 11.7 0.0 1.8 2 0 0 2 2 2 0 Helix-turn-helix domain ADK_lid PF05191.14 CBK20455.2 - 0.065 13.2 0.6 0.065 13.2 0.6 2.4 3 0 0 3 3 3 0 Adenylate kinase, active site lid Lactamase_B PF00753.27 CBK20459.2 - 1.4e-19 70.9 0.0 1.9e-19 70.5 0.0 1.1 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 CBK20459.2 - 0.0019 17.7 0.1 0.0025 17.4 0.1 1.4 1 1 0 1 1 1 1 Beta-lactamase superfamily domain RMMBL PF07521.12 CBK20459.2 - 0.039 13.9 0.1 0.069 13.1 0.1 1.3 1 0 0 1 1 1 0 Zn-dependent metallo-hydrolase RNA specificity domain Ribosomal_S6e PF01092.19 CBK20460.2 - 1e-56 190.3 0.0 1e-56 190.3 0.0 1.5 2 0 0 2 2 2 1 Ribosomal protein S6e MutS_III PF05192.18 CBK20461.2 - 3.2e-21 76.4 1.1 3.2e-21 76.4 1.1 1.7 2 1 0 2 2 2 1 MutS domain III MutS_V PF00488.21 CBK20462.2 - 3.7e-33 115.1 0.0 7.9e-33 114.1 0.0 1.5 1 1 0 1 1 1 1 MutS domain V DUF4821 PF16092.5 CBK20462.2 - 0.068 12.8 0.0 0.094 12.3 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4821) Nitroreductase PF00881.24 CBK20463.2 - 3.7e-21 75.9 0.0 1.7e-18 67.2 0.0 2.1 1 1 0 1 1 1 1 Nitroreductase family TM1586_NiRdase PF14512.6 CBK20463.2 - 3.2e-07 30.2 0.0 1.7e-06 27.8 0.0 1.8 1 1 0 1 1 1 1 Putative TM nitroreductase Pro_isomerase PF00160.21 CBK20464.2 - 4.5e-45 153.8 0.1 5.2e-45 153.5 0.1 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD PAP2_C PF14360.6 CBK20465.2 - 5.6e-10 39.6 7.5 2.8e-08 34.1 7.5 2.7 1 1 0 1 1 1 1 PAP2 superfamily C-terminal Cad PF03596.13 CBK20465.2 - 0.01 15.8 2.4 0.016 15.1 2.4 1.4 1 1 0 1 1 1 0 Cadmium resistance transporter PAP2 PF01569.21 CBK20465.2 - 0.039 13.7 4.2 0.15 11.9 2.4 2.3 2 1 0 2 2 2 0 PAP2 superfamily RRM_2 PF04059.12 CBK20466.2 - 2.9e-29 101.1 0.5 5e-29 100.4 0.5 1.3 1 0 0 1 1 1 1 RNA recognition motif 2 Cnd2 PF05786.14 CBK20467.2 - 1.6e-35 123.0 0.3 1.9e-35 122.8 0.3 1.1 1 0 0 1 1 1 1 Condensin complex subunit 2 CNDH2_N PF06278.11 CBK20467.2 - 0.00071 19.8 0.2 0.0016 18.7 0.2 1.5 1 1 0 1 1 1 1 Condensin II complex subunit CAP-H2 or CNDH2, N-terminal DUF4912 PF16258.5 CBK20468.2 - 0.075 13.3 0.0 0.09 13.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4912) Pan3_PK PF18101.1 CBK20469.2 - 1.1e-46 158.3 0.0 1.6e-46 157.7 0.0 1.3 1 0 0 1 1 1 1 Pan3 Pseudokinase domain Pkinase PF00069.25 CBK20469.2 - 1.2e-08 34.6 0.0 2.3e-08 33.8 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBK20469.2 - 4.9e-05 22.7 0.0 9.1e-05 21.9 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase INCENP_ARK-bind PF03941.15 CBK20470.2 - 2.5e-05 24.1 0.0 5.3e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 Inner centromere protein, ARK binding region SAP PF02037.27 CBK20470.2 - 0.0043 16.8 0.0 0.0078 16.0 0.0 1.5 1 0 0 1 1 1 1 SAP domain GDP_Man_Dehyd PF16363.5 CBK20471.2 - 3.2e-156 519.9 0.0 3.6e-156 519.7 0.0 1.0 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 CBK20471.2 - 2.9e-70 236.5 0.0 4e-70 236.0 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 CBK20471.2 - 0.00015 20.9 0.0 0.00045 19.4 0.0 1.6 2 0 0 2 2 2 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 CBK20471.2 - 0.0021 17.3 0.0 0.0041 16.3 0.0 1.4 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein NmrA PF05368.13 CBK20471.2 - 0.13 11.8 0.0 0.19 11.2 0.0 1.2 1 0 0 1 1 1 0 NmrA-like family adh_short PF00106.25 CBK20471.2 - 0.18 11.3 0.0 0.31 10.5 0.0 1.4 1 0 0 1 1 1 0 short chain dehydrogenase zf-TRAF PF02176.18 CBK20472.2 - 0.045 14.4 9.1 0.079 13.7 7.4 2.2 2 0 0 2 2 2 0 TRAF-type zinc finger MCR PF18509.1 CBK20472.2 - 0.089 12.4 0.2 0.19 11.3 0.2 1.6 1 0 0 1 1 1 0 Magnetochrome domain Asp-B-Hydro_N PF05279.11 CBK20472.2 - 0.7 9.9 13.7 0.92 9.5 13.7 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region PFK PF00365.20 CBK20473.2 - 4.3e-40 137.8 0.0 4.9e-38 131.1 0.0 2.2 2 0 0 2 2 2 2 Phosphofructokinase Helicase_C_3 PF13625.6 CBK20473.2 - 0.16 12.1 0.0 0.32 11.1 0.0 1.4 1 0 0 1 1 1 0 Helicase conserved C-terminal domain UQ_con PF00179.26 CBK20474.2 - 1.5e-31 108.9 1.6 7.3e-30 103.4 1.6 2.0 1 1 0 1 1 1 1 Ubiquitin-conjugating enzyme ATP_transf PF09830.9 CBK20475.2 - 5.8e-15 55.2 0.0 6.3e-15 55.1 0.0 1.0 1 0 0 1 1 1 1 ATP adenylyltransferase MAP70 PF07058.11 CBK20476.2 - 0.035 12.9 0.0 0.044 12.5 0.0 1.1 1 0 0 1 1 1 0 Microtubule-associated protein 70 DnaJ_C PF01556.18 CBK20477.2 - 6e-37 127.0 0.1 7.8e-37 126.6 0.1 1.1 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 CBK20477.2 - 3.1e-29 100.9 3.7 5.8e-29 100.0 3.7 1.5 1 0 0 1 1 1 1 DnaJ domain RPT PF13446.6 CBK20477.2 - 0.05 13.5 0.0 0.18 11.7 0.0 1.8 1 1 1 2 2 2 0 A repeated domain in UCH-protein LprI PF07007.12 CBK20477.2 - 0.13 12.9 0.1 0.22 12.2 0.1 1.3 1 0 0 1 1 1 0 Lysozyme inhibitor LprI PE_PPE_C PF12484.8 CBK20477.2 - 0.19 12.7 2.2 3.6 8.6 0.1 2.6 3 0 0 3 3 3 0 Polymorphic PE/PPE proteins C terminal Aa_trans PF01490.18 CBK20478.2 - 5.3e-38 130.8 31.7 6e-38 130.6 31.7 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein NiFe_hyd_3_EhaA PF17367.2 CBK20478.2 - 0.0091 16.1 1.9 0.0091 16.1 1.9 3.4 3 0 0 3 3 3 1 NiFe-hydrogenase-type-3 Eha complex subunit A GAD-like PF08887.11 CBK20478.2 - 0.092 12.5 0.1 1 9.2 0.0 2.3 2 0 0 2 2 2 0 GAD-like domain Copine PF07002.16 CBK20479.2 - 3.9e-16 59.2 0.0 6.3e-16 58.5 0.0 1.3 1 1 0 1 1 1 1 Copine EcKinase PF02958.20 CBK20479.2 - 0.071 12.4 0.0 0.092 12.0 0.0 1.1 1 0 0 1 1 1 0 Ecdysteroid kinase Copine PF07002.16 CBK20480.2 - 1.4e-08 34.5 0.1 1.6e-08 34.3 0.1 1.0 1 0 0 1 1 1 1 Copine PSP1 PF04468.12 CBK20481.2 - 7.2e-25 87.1 3.4 1.1e-24 86.5 2.6 1.7 2 0 0 2 2 2 1 PSP1 C-terminal conserved region Mito_carr PF00153.27 CBK20482.2 - 5.4e-50 167.3 5.3 7.8e-22 77.0 0.2 3.5 3 1 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 CBK20482.2 - 0.0081 15.4 0.4 0.12 11.5 0.0 2.5 2 1 1 3 3 3 1 Gammaproteobacterial serine protease Ank_4 PF13637.6 CBK20483.2 - 0.024 15.2 0.0 0.036 14.6 0.0 1.3 1 0 0 1 1 1 0 Ankyrin repeats (many copies) DUF2204 PF09970.9 CBK20485.2 - 0.17 11.5 0.0 0.22 11.1 0.0 1.1 1 0 0 1 1 1 0 Nucleotidyl transferase of unknown function (DUF2204) FoP_duplication PF13865.6 CBK20486.2 - 3.5e-09 37.1 8.3 3.5e-09 37.1 8.3 2.4 1 1 1 2 2 2 1 C-terminal duplication domain of Friend of PRMT1 Thioredoxin PF00085.20 CBK20487.2 - 0.035 14.1 0.0 0.051 13.6 0.0 1.4 1 1 0 1 1 1 0 Thioredoxin FliJ PF02050.16 CBK20488.2 - 0.0036 17.5 44.8 0.014 15.6 12.0 3.3 1 1 2 3 3 3 2 Flagellar FliJ protein PKcGMP_CC PF16808.5 CBK20488.2 - 0.0036 17.1 4.2 0.0058 16.5 0.6 3.3 2 0 0 2 2 2 1 Coiled-coil N-terminus of cGMP-dependent protein kinase KASH_CCD PF14662.6 CBK20488.2 - 0.0076 16.1 49.0 0.51 10.2 27.7 3.4 2 1 0 2 2 2 2 Coiled-coil region of CCDC155 or KASH CENP-F_leu_zip PF10473.9 CBK20488.2 - 0.028 14.5 52.3 0.25 11.3 6.7 3.2 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ATG16 PF08614.11 CBK20488.2 - 0.033 14.4 46.5 0.88 9.8 13.4 3.2 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) HMMR_N PF15905.5 CBK20488.2 - 0.046 13.2 51.8 0.031 13.7 26.7 2.8 1 1 2 3 3 3 0 Hyaluronan mediated motility receptor N-terminal DUF3584 PF12128.8 CBK20488.2 - 0.048 11.2 40.0 0.077 10.5 40.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) TPR_MLP1_2 PF07926.12 CBK20488.2 - 0.066 13.3 55.5 0.27 11.3 24.9 3.6 1 1 2 3 3 3 0 TPR/MLP1/MLP2-like protein TACC_C PF05010.14 CBK20488.2 - 0.068 12.9 44.6 0.52 10.1 24.5 3.2 1 1 1 2 2 2 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal PSD2 PF07624.11 CBK20488.2 - 0.072 12.9 4.1 0.19 11.5 0.7 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF1585) MAD PF05557.13 CBK20488.2 - 0.22 9.8 49.8 0.92 7.8 41.5 2.1 1 1 1 2 2 2 0 Mitotic checkpoint protein DUF4407 PF14362.6 CBK20488.2 - 0.36 10.1 37.4 2.7 7.2 23.9 3.0 1 1 2 3 3 3 0 Domain of unknown function (DUF4407) Filament PF00038.21 CBK20488.2 - 0.47 10.0 45.0 1.1 8.8 29.0 2.1 1 1 1 2 2 2 0 Intermediate filament protein Fez1 PF06818.15 CBK20488.2 - 0.65 10.4 46.4 0.11 12.9 19.7 2.5 1 1 1 2 2 2 0 Fez1 DUF812 PF05667.11 CBK20488.2 - 0.89 8.4 47.3 0.95 8.3 10.0 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF812) Prefoldin_2 PF01920.20 CBK20488.2 - 1 9.4 48.1 0.043 13.8 10.3 5.2 1 1 3 5 5 5 0 Prefoldin subunit MscS_porin PF12795.7 CBK20488.2 - 1 8.9 46.2 1.1 8.8 31.8 2.9 1 1 2 3 3 3 0 Mechanosensitive ion channel porin domain ABC_tran_CTD PF16326.5 CBK20488.2 - 1 9.6 50.2 2.6 8.4 4.5 5.1 1 1 4 5 5 5 0 ABC transporter C-terminal domain DUF745 PF05335.13 CBK20488.2 - 1.2 8.9 31.6 0.32 10.7 14.0 2.6 1 1 0 2 2 2 0 Protein of unknown function (DUF745) Sec8_exocyst PF04048.14 CBK20488.2 - 1.2 9.0 27.9 0.37 10.7 3.5 4.1 1 1 3 4 4 4 0 Sec8 exocyst complex component specific domain Exonuc_VII_L PF02601.15 CBK20488.2 - 1.2 8.6 36.9 0.4 10.2 14.6 2.1 1 1 1 2 2 2 0 Exonuclease VII, large subunit Spc7 PF08317.11 CBK20488.2 - 1.2 7.9 50.5 3.9 6.3 26.7 3.1 1 1 3 4 4 4 0 Spc7 kinetochore protein Golgin_A5 PF09787.9 CBK20488.2 - 1.4 8.3 48.3 31 3.9 28.8 2.6 1 1 1 2 2 2 0 Golgin subfamily A member 5 TMF_DNA_bd PF12329.8 CBK20488.2 - 1.4 8.9 51.1 0.68 10.0 5.9 5.0 1 1 4 5 5 4 0 TATA element modulatory factor 1 DNA binding GAS PF13851.6 CBK20488.2 - 1.6 8.0 49.2 4 6.7 11.3 3.6 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding FUSC PF04632.12 CBK20488.2 - 1.9 6.9 8.7 2.3 6.7 8.7 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family CCDC-167 PF15188.6 CBK20488.2 - 2 8.8 41.8 0.1 13.0 8.5 4.9 1 1 4 5 5 5 0 Coiled-coil domain-containing protein 167 DUF1664 PF07889.12 CBK20488.2 - 2.1 8.4 24.0 3.7 7.6 0.8 3.3 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) Baculo_PEP_C PF04513.12 CBK20488.2 - 2.3 8.3 12.9 4.6 7.3 7.9 3.1 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DivIC PF04977.15 CBK20488.2 - 2.6 7.9 44.1 0.34 10.7 2.2 5.7 1 1 6 7 7 7 0 Septum formation initiator FPP PF05911.11 CBK20488.2 - 2.9 6.0 46.6 10 4.1 17.8 2.1 1 1 1 2 2 2 0 Filament-like plant protein, long coiled-coil APG6_N PF17675.1 CBK20488.2 - 3.8 8.0 59.2 1.9 9.0 25.1 3.6 1 1 2 3 3 3 0 Apg6 coiled-coil region ADIP PF11559.8 CBK20488.2 - 4.2 7.4 47.2 1 9.4 17.4 3.9 1 1 3 4 4 4 0 Afadin- and alpha -actinin-Binding DUF1515 PF07439.11 CBK20488.2 - 4.3 7.4 15.3 2.1 8.4 1.1 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1515) Occludin_ELL PF07303.13 CBK20488.2 - 5.2 7.9 34.8 1.6 9.5 2.3 4.2 1 1 2 3 3 2 0 Occludin homology domain EzrA PF06160.12 CBK20488.2 - 5.3 5.1 47.0 0.39 8.9 16.9 3.2 1 1 2 3 3 3 0 Septation ring formation regulator, EzrA THOC7 PF05615.13 CBK20488.2 - 6.1 7.1 45.0 0.43 10.9 15.1 3.7 1 1 2 3 3 3 0 Tho complex subunit 7 OmpH PF03938.14 CBK20488.2 - 7 7.0 54.7 37 4.6 23.2 3.7 1 1 2 3 3 3 0 Outer membrane protein (OmpH-like) Cep57_MT_bd PF06657.13 CBK20488.2 - 9.2 6.8 37.0 2 8.9 8.9 4.8 2 2 1 4 4 4 0 Centrosome microtubule-binding domain of Cep57 DUF3361 PF11841.8 CBK20489.2 - 0.04 13.9 8.0 0.59 10.1 1.5 3.0 1 1 0 2 2 2 0 Domain of unknown function (DUF3361) Ras PF00071.22 CBK20490.2 - 7.4e-15 54.9 0.2 8.3e-15 54.7 0.2 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CBK20490.2 - 7.4e-12 45.6 0.1 8.6e-12 45.3 0.1 1.0 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CBK20490.2 - 0.018 14.5 0.1 0.021 14.3 0.1 1.0 1 0 0 1 1 1 0 ADP-ribosylation factor family zf-C3HC4_4 PF15227.6 CBK20491.2 - 4.4e-07 30.0 12.3 1.4e-06 28.4 12.3 1.9 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.6 CBK20491.2 - 2.8e-06 27.1 12.2 5.9e-06 26.1 12.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CBK20491.2 - 0.00012 21.9 13.8 0.00029 20.7 13.8 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CBK20491.2 - 0.00038 20.4 9.7 0.0012 18.9 9.7 1.9 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 CBK20491.2 - 0.00097 18.9 12.5 0.00097 18.9 12.5 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 CBK20491.2 - 0.0017 18.2 11.8 0.0034 17.2 11.8 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 CBK20491.2 - 0.0025 17.7 15.0 0.0031 17.4 13.3 2.1 1 1 1 2 2 2 1 zinc-RING finger domain RTT107_BRCT_5 PF16770.5 CBK20491.2 - 0.0026 17.6 0.0 0.0076 16.1 0.0 1.8 1 0 0 1 1 1 1 Regulator of Ty1 transposition protein 107 BRCT domain zf-RING_10 PF16685.5 CBK20491.2 - 0.0031 17.6 10.4 0.007 16.5 10.4 1.6 1 0 0 1 1 1 1 zinc RING finger of MSL2 zf-RING_2 PF13639.6 CBK20491.2 - 0.0076 16.6 14.1 0.0089 16.3 12.7 2.0 2 0 0 2 2 2 1 Ring finger domain zf-RING_6 PF14835.6 CBK20491.2 - 0.01 15.7 7.8 0.024 14.5 7.8 1.6 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-UDP PF14569.6 CBK20491.2 - 0.011 15.8 0.2 0.049 13.8 0.3 2.0 2 0 0 2 2 1 0 Zinc-binding RING-finger zf-RING_4 PF14570.6 CBK20491.2 - 2.5 7.9 10.6 9.8 6.1 10.6 2.0 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain S1-P1_nuclease PF02265.16 CBK20492.2 - 1.2e-15 58.0 0.1 1.5e-15 57.8 0.1 1.1 1 0 0 1 1 1 1 S1/P1 Nuclease BPL_LplA_LipB PF03099.19 CBK20495.2 - 2.2e-16 59.9 0.3 4e-16 59.1 0.3 1.4 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family BPL_C PF02237.17 CBK20495.2 - 2.6e-09 36.9 0.0 5.9e-09 35.7 0.0 1.6 1 0 0 1 1 1 1 Biotin protein ligase C terminal domain TPR_14 PF13428.6 CBK20496.2 - 7.1e-08 32.6 3.0 0.0014 19.3 0.2 4.0 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 CBK20496.2 - 4.3e-05 23.3 5.6 0.015 15.3 0.1 3.9 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 CBK20496.2 - 5.4e-05 23.6 2.2 0.015 15.8 0.1 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 CBK20496.2 - 0.00012 21.7 5.2 0.012 15.4 0.1 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.6 CBK20496.2 - 0.0014 18.7 0.8 0.94 9.7 0.0 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat ANAPC3 PF12895.7 CBK20496.2 - 0.0034 17.6 5.8 0.25 11.6 1.9 3.0 3 0 0 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_20 PF14561.6 CBK20496.2 - 0.0084 16.4 2.0 0.046 14.0 0.0 2.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.6 CBK20496.2 - 0.0085 16.7 2.3 0.32 11.7 0.1 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 CBK20496.2 - 0.021 15.0 3.4 0.067 13.4 0.1 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 CBK20496.2 - 0.048 13.7 2.4 1.6 8.9 0.2 3.3 3 0 0 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat TPR_17 PF13431.6 CBK20496.2 - 0.12 12.8 2.3 1.4 9.5 0.0 3.5 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_16 PF13432.6 CBK20496.2 - 0.18 12.5 0.3 0.92 10.2 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_11 PF13414.6 CBK20496.2 - 1.7 8.4 6.6 0.87 9.3 0.1 3.4 3 1 1 4 4 4 0 TPR repeat UFD1 PF03152.14 CBK20497.2 - 3.8e-05 23.2 0.0 4.5e-05 23.0 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 Pkinase PF00069.25 CBK20498.2 - 1.8e-36 125.8 0.0 2e-36 125.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBK20498.2 - 1.4e-12 47.4 0.0 1.7e-12 47.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PIP49_C PF12260.8 CBK20498.2 - 0.016 14.8 0.0 0.026 14.2 0.0 1.2 1 0 0 1 1 1 0 Protein-kinase domain of FAM69 Seadorna_VP7 PF07387.11 CBK20498.2 - 0.019 14.0 0.0 0.026 13.6 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Choline_kinase PF01633.20 CBK20498.2 - 0.078 12.6 0.7 0.1 12.1 0.7 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase LHH PF14411.6 CBK20498.2 - 0.088 13.0 0.1 0.15 12.3 0.1 1.3 1 0 0 1 1 1 0 A nuclease of the HNH/ENDO VII superfamily with conserved LHH APH PF01636.23 CBK20498.2 - 0.093 12.6 0.0 0.14 12.1 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family AP4E_app_platf PF14807.6 CBK20498.2 - 0.098 13.0 0.0 0.8 10.1 0.0 2.0 2 0 0 2 2 2 0 Adaptin AP4 complex epsilon appendage platform DUF1725 PF08333.11 CBK20498.2 - 1.6 8.5 4.2 8.6 6.2 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1725) He_PIG PF05345.12 CBK20499.2 - 1.6e-12 47.4 17.5 6.1e-05 23.1 0.0 6.6 7 0 0 7 7 7 4 Putative Ig domain PA14 PF07691.12 CBK20499.2 - 1.4e-11 44.4 0.1 0.00016 21.5 0.0 2.9 3 0 0 3 3 3 2 PA14 domain GLEYA PF10528.9 CBK20499.2 - 0.022 15.1 2.1 4.8 7.7 0.5 3.6 2 1 0 2 2 2 0 GLEYA domain HRM PF02793.22 CBK20499.2 - 0.13 12.5 0.3 0.34 11.2 0.3 1.6 1 0 0 1 1 1 0 Hormone receptor domain RabGAP-TBC PF00566.18 CBK20500.2 - 5.8e-49 166.7 0.5 1e-48 165.9 0.5 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain GDI PF00996.18 CBK20501.2 - 9.3e-172 571.4 1.1 1.2e-171 571.1 1.1 1.0 1 0 0 1 1 1 1 GDP dissociation inhibitor Amino_oxidase PF01593.24 CBK20501.2 - 0.0085 15.4 0.0 0.019 14.3 0.0 1.6 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase Pyr_redox PF00070.27 CBK20501.2 - 0.021 15.4 0.0 0.53 10.9 0.0 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 CBK20501.2 - 0.04 14.1 0.0 0.078 13.2 0.0 1.4 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 CBK20501.2 - 0.071 12.3 0.0 0.13 11.5 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain Pkinase PF00069.25 CBK20502.2 - 1.8e-50 171.8 0.2 8.5e-50 169.6 0.2 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBK20502.2 - 4.7e-25 88.3 0.0 6.9e-25 87.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CBK20502.2 - 0.045 13.1 0.3 0.071 12.4 0.3 1.5 1 1 0 1 1 1 0 Kinase-like PHD PF00628.29 CBK20503.2 - 6.7e-12 45.1 10.8 1e-11 44.5 8.2 2.4 2 0 0 2 2 2 1 PHD-finger SET PF00856.28 CBK20503.2 - 0.00014 22.3 0.1 0.037 14.4 0.0 2.7 2 1 0 2 2 2 1 SET domain Prok-RING_1 PF14446.6 CBK20503.2 - 0.0054 16.6 1.3 0.014 15.4 1.3 1.7 1 0 0 1 1 1 1 Prokaryotic RING finger family 1 PHD_2 PF13831.6 CBK20503.2 - 0.0097 15.4 3.5 0.0097 15.4 3.5 2.1 2 0 0 2 2 2 1 PHD-finger Glyco_hydro_36 PF17167.4 CBK20503.2 - 0.085 11.5 0.1 0.12 11.0 0.1 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase 36 superfamily, catalytic domain Zf_RING PF16744.5 CBK20503.2 - 0.11 12.6 0.5 0.11 12.6 0.5 2.2 3 0 0 3 3 3 0 KIAA1045 RING finger zf-RING_2 PF13639.6 CBK20503.2 - 0.23 11.8 7.4 0.79 10.1 7.4 2.0 1 1 0 1 1 1 0 Ring finger domain Ribosomal_S13_N PF08069.12 CBK20504.2 - 2.7e-29 101.0 0.3 6.9e-29 99.7 0.1 1.8 2 0 0 2 2 2 1 Ribosomal S13/S15 N-terminal domain Ribosomal_S15 PF00312.22 CBK20504.2 - 7.1e-16 58.2 0.8 9.1e-16 57.8 0.8 1.2 1 0 0 1 1 1 1 Ribosomal protein S15 GrpE PF01025.19 CBK20505.2 - 2.2e-38 131.5 0.1 2.9e-38 131.2 0.1 1.0 1 0 0 1 1 1 1 GrpE DUF2913 PF11140.8 CBK20505.2 - 0.00047 19.9 0.3 0.0008 19.2 0.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2913) Prefoldin PF02996.17 CBK20505.2 - 0.0012 18.8 7.1 0.0013 18.6 2.8 2.6 3 0 0 3 3 3 1 Prefoldin subunit YojJ PF10372.9 CBK20505.2 - 0.0082 16.2 0.1 0.015 15.4 0.1 1.4 1 0 0 1 1 1 1 Bacterial membrane-spanning protein N-terminus Lge1 PF11488.8 CBK20505.2 - 0.011 15.9 2.6 0.011 15.9 2.6 1.7 2 0 0 2 2 2 0 Transcriptional regulatory protein LGE1 CHDCT2 PF08074.11 CBK20505.2 - 0.013 15.7 0.0 0.025 14.7 0.0 1.5 1 0 0 1 1 1 0 CHDCT2 (NUC038) domain CCDC-167 PF15188.6 CBK20505.2 - 0.017 15.5 1.0 0.033 14.5 1.0 1.4 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 167 Myosin_tail_1 PF01576.19 CBK20505.2 - 0.023 12.6 2.9 0.03 12.1 2.9 1.0 1 0 0 1 1 1 0 Myosin tail YabA PF06156.13 CBK20505.2 - 0.031 14.9 0.2 0.05 14.2 0.2 1.4 1 0 0 1 1 1 0 Initiation control protein YabA FlxA PF14282.6 CBK20505.2 - 0.063 13.3 1.9 0.11 12.4 1.9 1.4 1 0 0 1 1 1 0 FlxA-like protein Spc24 PF08286.11 CBK20505.2 - 0.083 13.1 1.0 0.11 12.7 1.0 1.3 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 FapA PF03961.13 CBK20505.2 - 0.2 10.2 1.8 6.9 5.2 0.8 2.0 2 0 0 2 2 2 0 Flagellar Assembly Protein A DivIC PF04977.15 CBK20505.2 - 0.49 10.2 2.5 0.86 9.4 2.5 1.4 1 0 0 1 1 1 0 Septum formation initiator MFS_1 PF07690.16 CBK20506.2 - 2.9e-16 59.3 31.2 2.9e-16 59.3 31.2 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.16 CBK20506.2 - 1.1e-05 25.2 15.8 1.1e-05 25.2 15.8 3.1 3 1 0 3 3 3 1 Ion channel regulatory protein UNC-93 Ins134_P3_kin PF05770.11 CBK20507.2 - 6.2e-19 68.3 0.0 8.6e-19 67.8 0.0 1.2 1 0 0 1 1 1 1 Inositol 1,3,4-trisphosphate 5/6-kinase ATP-grasp domain Ins134_P3_kin_N PF17927.1 CBK20507.2 - 0.00072 19.9 0.0 0.0015 18.9 0.0 1.5 1 0 0 1 1 1 1 Inositol 1,3,4-trisphosphate 5/6-kinase pre-ATP-grasp domain AAA_2 PF07724.14 CBK20508.2 - 5.7e-54 182.8 0.0 4.6e-52 176.6 0.0 2.9 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_lid_9 PF17871.1 CBK20508.2 - 9.7e-37 125.1 2.7 9.7e-37 125.1 2.7 3.2 3 0 0 3 3 2 1 AAA lid domain AAA PF00004.29 CBK20508.2 - 4.6e-27 95.0 0.2 2.5e-15 57.1 0.0 3.3 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.9 CBK20508.2 - 2.4e-21 75.6 2.0 9.5e-21 73.7 0.2 2.9 2 0 0 2 2 2 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.14 CBK20508.2 - 2.5e-16 59.9 0.9 1e-10 41.8 0.0 3.5 3 1 0 3 3 2 2 AAA domain (dynein-related subfamily) Clp_N PF02861.20 CBK20508.2 - 3.7e-13 49.4 0.1 5.3e-05 23.3 0.0 3.5 3 0 0 3 3 3 2 Clp amino terminal domain, pathogenicity island component AAA_16 PF13191.6 CBK20508.2 - 3.5e-12 47.0 8.3 5.2e-06 27.0 0.0 5.1 4 2 1 6 6 4 2 AAA ATPase domain AAA_22 PF13401.6 CBK20508.2 - 4.3e-12 46.5 0.1 0.00075 19.8 0.0 4.7 2 2 0 2 2 2 2 AAA domain AAA_14 PF13173.6 CBK20508.2 - 8.9e-08 32.2 1.2 0.012 15.6 0.0 3.5 4 0 0 4 4 2 2 AAA domain IstB_IS21 PF01695.17 CBK20508.2 - 1.1e-07 31.8 0.0 0.018 14.8 0.0 2.7 2 0 0 2 2 2 2 IstB-like ATP binding protein TniB PF05621.11 CBK20508.2 - 2.7e-07 30.2 0.1 0.0023 17.3 0.1 4.0 2 1 0 2 2 2 1 Bacterial TniB protein Sigma54_activat PF00158.26 CBK20508.2 - 6.5e-07 29.2 0.0 0.00016 21.4 0.0 2.8 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_7 PF12775.7 CBK20508.2 - 9e-07 28.6 0.0 0.0079 15.7 0.0 2.8 2 1 0 2 2 2 2 P-loop containing dynein motor region Roc PF08477.13 CBK20508.2 - 2e-05 24.8 0.0 0.38 11.0 0.0 2.8 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase NACHT PF05729.12 CBK20508.2 - 3.9e-05 23.6 0.0 0.19 11.6 0.0 2.7 2 0 0 2 2 2 2 NACHT domain RuvB_N PF05496.12 CBK20508.2 - 5.4e-05 23.0 1.6 0.17 11.6 0.0 4.1 3 1 0 3 3 2 1 Holliday junction DNA helicase RuvB P-loop domain ATPase_2 PF01637.18 CBK20508.2 - 5.7e-05 23.1 11.1 0.62 9.9 0.1 5.0 4 1 2 6 6 5 3 ATPase domain predominantly from Archaea RNA_helicase PF00910.22 CBK20508.2 - 9.2e-05 22.8 0.0 0.37 11.2 0.0 3.2 3 0 0 3 3 2 1 RNA helicase DUF815 PF05673.13 CBK20508.2 - 0.00021 20.6 0.1 0.028 13.6 0.0 2.7 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_25 PF13481.6 CBK20508.2 - 0.00022 20.9 0.2 0.13 11.8 0.0 3.6 4 0 0 4 4 3 1 AAA domain AAA_28 PF13521.6 CBK20508.2 - 0.00023 21.5 1.3 1.4 9.1 0.0 4.0 4 0 0 4 4 3 1 AAA domain AAA_33 PF13671.6 CBK20508.2 - 0.00035 20.8 0.0 0.79 9.9 0.0 3.8 3 0 0 3 3 3 1 AAA domain RsgA_GTPase PF03193.16 CBK20508.2 - 0.0013 18.7 0.5 2.5 8.0 0.0 3.0 3 0 0 3 3 2 2 RsgA GTPase TsaE PF02367.17 CBK20508.2 - 0.0017 18.4 0.0 4.2 7.4 0.0 3.1 3 0 0 3 3 3 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE Zeta_toxin PF06414.12 CBK20508.2 - 0.0018 17.6 0.0 0.14 11.4 0.0 2.8 2 0 0 2 2 2 1 Zeta toxin Mg_chelatase PF01078.21 CBK20508.2 - 0.0021 17.5 0.0 2.4 7.5 0.0 3.1 2 1 1 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_24 PF13479.6 CBK20508.2 - 0.0027 17.5 0.0 3.2 7.4 0.0 3.3 3 0 0 3 3 3 1 AAA domain AAA_19 PF13245.6 CBK20508.2 - 0.0028 18.0 0.9 1.8 8.9 0.1 4.3 4 1 1 5 5 4 1 AAA domain AAA_18 PF13238.6 CBK20508.2 - 0.0035 17.9 7.7 0.35 11.4 0.0 3.9 4 1 1 5 5 2 2 AAA domain ResIII PF04851.15 CBK20508.2 - 0.0042 17.1 0.0 0.32 11.0 0.0 3.5 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit AAA_3 PF07726.11 CBK20508.2 - 0.0055 16.6 0.0 4.2 7.2 0.0 3.2 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) NTPase_1 PF03266.15 CBK20508.2 - 0.012 15.5 0.0 5.9 6.8 0.0 2.8 2 0 0 2 2 2 0 NTPase SRP54 PF00448.22 CBK20508.2 - 0.013 15.1 4.3 0.35 10.5 0.0 3.6 4 0 0 4 4 4 0 SRP54-type protein, GTPase domain DNA_pol3_delta2 PF13177.6 CBK20508.2 - 0.014 15.1 0.0 0.36 10.6 0.0 2.7 2 0 0 2 2 2 0 DNA polymerase III, delta subunit PhoH PF02562.16 CBK20508.2 - 0.017 14.6 0.1 0.99 8.8 0.0 3.1 3 0 0 3 3 3 0 PhoH-like protein T2SSE PF00437.20 CBK20508.2 - 0.022 13.9 0.0 0.074 12.1 0.0 1.9 1 0 0 1 1 1 0 Type II/IV secretion system protein Ras PF00071.22 CBK20508.2 - 0.062 12.9 0.1 23 4.6 0.0 3.3 3 0 0 3 3 3 0 Ras family AAA_29 PF13555.6 CBK20508.2 - 0.097 12.4 0.0 21 4.9 0.0 2.6 2 0 0 2 2 2 0 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 CBK20508.2 - 0.16 12.1 0.2 18 5.5 0.0 3.7 4 0 0 4 4 3 0 50S ribosome-binding GTPase AAA_23 PF13476.6 CBK20508.2 - 0.22 12.0 0.0 0.22 12.0 0.0 4.8 3 1 0 3 3 2 0 AAA domain DUF87 PF01935.17 CBK20508.2 - 0.42 10.7 6.8 0.58 10.2 0.0 3.7 4 0 0 4 4 4 0 Helicase HerA, central domain ABC_tran PF00005.27 CBK20508.2 - 1.7 9.2 8.1 2.4 8.7 0.0 3.7 4 2 0 4 4 2 0 ABC transporter Arf PF00025.21 CBK20510.2 - 4.1e-65 218.5 0.1 4.7e-65 218.3 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.20 CBK20510.2 - 6.9e-15 55.0 4.3 2e-09 37.1 0.4 2.1 1 1 1 2 2 2 2 G-protein alpha subunit Roc PF08477.13 CBK20510.2 - 3e-12 46.8 0.2 4.2e-12 46.3 0.2 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 CBK20510.2 - 6.9e-11 42.0 0.0 8.4e-11 41.7 0.0 1.1 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 CBK20510.2 - 1.1e-09 38.0 0.0 1.4e-09 37.6 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 CBK20510.2 - 2e-09 37.1 0.0 2.8e-09 36.7 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 CBK20510.2 - 3.1e-07 30.5 0.0 4.2e-07 30.1 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 CBK20510.2 - 0.0012 18.5 0.0 0.0048 16.4 0.0 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.18 CBK20510.2 - 0.014 15.0 0.2 0.047 13.2 0.1 1.9 1 1 0 1 1 1 0 Ferrous iron transport protein B AIG1 PF04548.16 CBK20510.2 - 0.048 13.0 0.0 0.087 12.1 0.0 1.4 1 0 0 1 1 1 0 AIG1 family cobW PF02492.19 CBK20510.2 - 0.057 13.0 0.1 0.85 9.2 0.0 2.0 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain MeaB PF03308.16 CBK20510.2 - 0.11 11.4 0.0 0.3 10.0 0.0 1.6 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB PduV-EutP PF10662.9 CBK20510.2 - 0.15 11.8 0.2 0.22 11.3 0.2 1.7 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation WD40 PF00400.32 CBK20512.2 - 1e-10 42.0 5.9 0.0002 22.1 0.0 4.4 4 0 0 4 4 4 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBK20512.2 - 1.2e-05 25.5 0.0 0.34 11.2 0.0 3.3 1 1 2 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 CBK20512.2 - 0.12 11.7 0.0 2.6 7.3 0.0 2.3 2 1 0 2 2 2 0 WD40-like domain WD40 PF00400.32 CBK20513.2 - 5.6e-47 156.8 18.2 1.2e-10 41.8 0.1 7.2 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBK20513.2 - 4.1e-10 39.8 4.5 0.0063 16.8 0.0 5.5 2 2 4 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 CBK20513.2 - 1.3e-06 27.4 6.9 0.015 14.0 0.1 5.0 3 1 1 5 5 5 3 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 CBK20513.2 - 8.3e-06 25.0 0.3 0.04 12.9 0.0 3.6 2 1 2 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein PQQ_2 PF13360.6 CBK20513.2 - 0.0064 16.1 1.7 0.083 12.5 0.0 2.3 2 1 0 2 2 2 1 PQQ-like domain DUF1513 PF07433.11 CBK20513.2 - 0.0094 15.1 0.3 0.97 8.4 0.1 3.0 1 1 3 4 4 4 1 Protein of unknown function (DUF1513) Cytochrom_D1 PF02239.16 CBK20513.2 - 0.02 13.5 0.0 0.94 7.9 0.0 2.9 2 2 1 3 3 3 0 Cytochrome D1 heme domain PQQ_3 PF13570.6 CBK20513.2 - 0.075 13.5 0.7 18 6.0 0.1 3.8 3 1 0 3 3 3 0 PQQ-like domain Ribosomal_L37e PF01907.19 CBK20514.2 - 3.6e-27 94.3 11.2 3.6e-27 94.3 11.2 1.6 2 0 0 2 2 2 1 Ribosomal protein L37e HypA PF01155.19 CBK20514.2 - 0.015 15.3 0.2 0.02 14.9 0.2 1.2 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-RING_10 PF16685.5 CBK20514.2 - 0.07 13.3 1.5 0.097 12.8 1.5 1.2 1 0 0 1 1 1 0 zinc RING finger of MSL2 Actin PF00022.19 CBK20515.2 - 4.1e-139 463.7 0.0 4.1e-138 460.4 0.0 1.9 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.13 CBK20515.2 - 0.0087 14.9 0.0 0.03 13.1 0.0 1.9 2 0 0 2 2 2 1 MreB/Mbl protein Methyltransf_29 PF03141.16 CBK20515.2 - 0.043 12.4 0.0 0.058 11.9 0.0 1.2 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase POR_N PF01855.19 CBK20516.2 - 2.2e-72 243.5 0.4 6.3e-72 242.0 0.1 1.9 2 0 0 2 2 2 1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg FAD_binding_1 PF00667.20 CBK20516.2 - 3.8e-42 144.3 0.0 6.8e-42 143.5 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 CBK20516.2 - 2.8e-25 89.2 0.1 7e-25 87.9 0.1 1.7 1 0 0 1 1 1 1 Flavodoxin POR PF01558.18 CBK20516.2 - 2.2e-22 80.0 0.0 5.9e-22 78.6 0.0 1.8 1 0 0 1 1 1 1 Pyruvate ferredoxin/flavodoxin oxidoreductase EKR PF10371.9 CBK20516.2 - 8.6e-19 67.1 0.6 2.2e-18 65.8 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function PFOR_II PF17147.4 CBK20516.2 - 7.2e-12 45.5 0.0 2.5e-11 43.8 0.0 2.0 1 0 0 1 1 1 1 Pyruvate:ferredoxin oxidoreductase core domain II Fer4_7 PF12838.7 CBK20516.2 - 5.1e-08 33.4 8.1 2.5e-07 31.2 8.3 2.3 1 1 0 1 1 1 1 4Fe-4S dicluster domain TPP_enzyme_C PF02775.21 CBK20516.2 - 2.5e-07 30.6 0.1 5.8e-07 29.4 0.1 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Fer4_16 PF13484.6 CBK20516.2 - 2.8e-07 31.3 10.5 2e-05 25.4 11.7 2.7 1 1 1 2 2 2 2 4Fe-4S double cluster binding domain NAD_binding_1 PF00175.21 CBK20516.2 - 3.2e-07 31.0 0.0 1.1e-06 29.2 0.0 2.0 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Fer4_9 PF13187.6 CBK20516.2 - 5.5e-07 29.7 11.4 0.0026 17.9 1.6 2.8 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4 PF00037.27 CBK20516.2 - 2.4e-06 27.1 23.7 0.00023 20.8 5.5 3.5 3 0 0 3 3 3 2 4Fe-4S binding domain Fer4_10 PF13237.6 CBK20516.2 - 1.4e-05 25.1 8.9 1.4e-05 25.1 8.9 2.3 3 0 0 3 3 1 1 4Fe-4S dicluster domain Fer4_21 PF14697.6 CBK20516.2 - 0.00024 21.2 14.8 0.0024 18.0 14.8 2.6 1 1 0 1 1 1 1 4Fe-4S dicluster domain Transketolase_C PF02780.20 CBK20516.2 - 0.00043 20.2 0.6 0.0018 18.1 0.1 2.3 2 0 0 2 2 2 1 Transketolase, C-terminal domain Fer4_6 PF12837.7 CBK20516.2 - 0.00052 20.0 6.7 0.00052 20.0 6.7 3.6 3 0 0 3 3 3 2 4Fe-4S binding domain Fer4_17 PF13534.6 CBK20516.2 - 0.00083 19.8 11.5 0.019 15.5 2.0 3.5 3 0 0 3 3 2 2 4Fe-4S dicluster domain Fer4_2 PF12797.7 CBK20516.2 - 0.0075 16.3 18.5 0.017 15.2 2.7 3.5 3 0 0 3 3 3 2 4Fe-4S binding domain Fer4_18 PF13746.6 CBK20516.2 - 0.036 14.3 5.7 1.5 9.1 0.8 3.0 3 0 0 3 3 2 0 4Fe-4S dicluster domain Fer4_8 PF13183.6 CBK20516.2 - 0.04 14.4 13.3 0.23 11.9 13.1 2.5 1 1 2 3 3 3 0 4Fe-4S dicluster domain Fer4_15 PF13459.6 CBK20516.2 - 0.79 10.5 7.6 10 6.9 0.3 3.0 2 0 0 2 2 2 0 4Fe-4S single cluster domain Fer4_22 PF17179.4 CBK20516.2 - 4.3 8.3 9.0 5 8.0 2.2 3.0 2 0 0 2 2 2 0 4Fe-4S dicluster domain PseudoU_synth_1 PF01416.20 CBK20517.2 - 1.7e-11 44.5 0.0 3.4e-11 43.6 0.0 1.5 1 0 0 1 1 1 1 tRNA pseudouridine synthase DUF2344 PF10105.9 CBK20517.2 - 0.062 13.1 0.0 0.086 12.7 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2344) DUF1883 PF08980.10 CBK20517.2 - 0.17 11.8 0.0 2 8.4 0.0 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF1883) GTP_EFTU PF00009.27 CBK20518.2 - 2.4e-54 183.8 0.0 3.6e-54 183.3 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 CBK20518.2 - 3.2e-40 136.9 0.0 7.9e-40 135.7 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 CBK20518.2 - 9.5e-08 32.3 0.0 2.7e-07 30.9 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 CBK20518.2 - 0.00011 22.3 0.1 0.0022 18.1 0.1 2.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase Glyco_hydro_35 PF01301.19 CBK20519.2 - 7.3e-108 360.9 1.9 9.2e-108 360.6 1.9 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 Glyco_hydro_42 PF02449.15 CBK20519.2 - 3.7e-14 52.9 0.1 1.5e-12 47.6 0.1 2.4 1 1 0 1 1 1 1 Beta-galactosidase Cellulase PF00150.18 CBK20519.2 - 0.06 12.8 0.2 0.16 11.4 0.0 1.7 2 0 0 2 2 2 0 Cellulase (glycosyl hydrolase family 5) NIF PF03031.18 CBK20520.2 - 2.8e-38 131.2 1.3 2.2e-37 128.2 1.3 2.0 1 1 0 1 1 1 1 NLI interacting factor-like phosphatase Pkinase PF00069.25 CBK20521.2 - 1.3e-34 119.8 0.0 1.6e-34 119.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBK20521.2 - 3.6e-09 36.3 0.0 5.7e-09 35.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 CBK20521.2 - 0.039 13.9 0.0 9.1 6.1 0.1 2.4 1 1 1 2 2 2 0 Phosphotransferase enzyme family FTA2 PF13095.6 CBK20521.2 - 0.13 11.8 0.0 0.22 11.1 0.0 1.3 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Pkinase_fungal PF17667.1 CBK20521.2 - 0.17 10.7 0.0 0.19 10.5 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Thioredoxin PF00085.20 CBK20522.2 - 0.00074 19.5 0.0 0.0008 19.4 0.0 1.0 1 0 0 1 1 1 1 Thioredoxin Sep15_SelM PF08806.11 CBK20522.2 - 0.096 12.9 0.0 0.11 12.6 0.0 1.2 1 0 0 1 1 1 0 Sep15/SelM redox domain Thioredoxin PF00085.20 CBK20523.2 - 0.00012 22.0 0.1 0.00022 21.2 0.1 1.4 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_7 PF13899.6 CBK20523.2 - 0.044 14.0 0.3 0.09 13.0 0.1 1.6 2 0 0 2 2 2 0 Thioredoxin-like Thioredoxin_2 PF13098.6 CBK20523.2 - 0.048 14.1 0.2 0.12 12.9 0.0 1.7 2 0 0 2 2 2 0 Thioredoxin-like domain PLU-1 PF08429.11 CBK20523.2 - 0.094 11.9 0.1 0.11 11.6 0.1 1.1 1 0 0 1 1 1 0 PLU-1-like protein EF-hand_7 PF13499.6 CBK20524.2 - 9.1e-14 51.7 0.3 2.2e-06 28.0 0.1 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 CBK20524.2 - 5.6e-12 44.6 0.9 5.1e-06 26.0 0.1 3.0 2 1 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.32 CBK20524.2 - 9.8e-11 40.4 0.2 8.2e-05 21.9 0.0 3.0 2 0 0 2 2 2 2 EF hand EF-hand_5 PF13202.6 CBK20524.2 - 3.3e-08 32.6 2.3 0.0093 15.4 0.1 3.2 2 1 1 3 3 3 2 EF hand EF-hand_8 PF13833.6 CBK20524.2 - 0.00021 21.0 3.7 1.6 8.7 0.0 3.8 4 1 0 4 4 4 2 EF-hand domain pair EF-hand_9 PF14658.6 CBK20524.2 - 0.0018 18.5 0.1 0.075 13.4 0.0 2.3 2 0 0 2 2 2 1 EF-hand domain EF-hand_11 PF08976.11 CBK20524.2 - 0.0062 17.4 0.0 0.0081 17.0 0.0 1.3 1 0 0 1 1 1 1 EF-hand domain Dockerin_1 PF00404.18 CBK20524.2 - 0.014 15.6 0.2 2.1 8.6 0.0 2.4 2 0 0 2 2 2 0 Dockerin type I domain Caleosin PF05042.13 CBK20524.2 - 0.033 14.1 0.3 4.8 7.1 0.1 2.2 1 1 1 2 2 2 0 Caleosin related protein DUF5580 PF17743.1 CBK20524.2 - 0.17 10.4 0.2 0.36 9.3 0.0 1.5 2 0 0 2 2 2 0 Family of unknown function (DUF5580) Got1 PF04178.12 CBK20525.2 - 6e-24 84.6 14.4 8.1e-24 84.2 14.1 1.3 1 1 0 1 1 1 1 Got1/Sft2-like family DUF2070 PF09843.9 CBK20525.2 - 1.1 7.5 11.4 1.2 7.3 11.4 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) RAI16-like PF10257.9 CBK20527.2 - 0.00013 21.0 0.1 0.00021 20.3 0.1 1.3 1 0 0 1 1 1 1 Retinoic acid induced 16-like protein FANCI_S4 PF14678.6 CBK20527.2 - 0.027 13.6 0.8 0.064 12.4 0.7 1.6 1 1 1 2 2 2 0 FANCI solenoid 4 Nnf1 PF03980.14 CBK20527.2 - 0.08 13.3 1.2 0.098 13.0 1.2 1.3 1 1 0 1 1 1 0 Nnf1 Enolase_C PF00113.22 CBK20528.2 - 7.1e-148 491.6 0.1 1.1e-147 491.0 0.1 1.3 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.16 CBK20528.2 - 4.4e-56 188.6 0.3 7.3e-56 187.9 0.3 1.4 1 0 0 1 1 1 1 Enolase, N-terminal domain MR_MLE_C PF13378.6 CBK20528.2 - 3e-09 36.8 0.0 5.1e-09 36.0 0.0 1.3 1 0 0 1 1 1 1 Enolase C-terminal domain-like MAAL_C PF07476.11 CBK20528.2 - 1.8e-05 24.0 0.1 3e-05 23.3 0.1 1.3 1 0 0 1 1 1 1 Methylaspartate ammonia-lyase C-terminus HMA PF00403.26 CBK20528.2 - 0.73 10.3 5.3 53 4.4 0.0 4.2 5 0 0 5 5 5 0 Heavy-metal-associated domain Alpha-amylase PF00128.24 CBK20529.2 - 0.074 12.6 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 Alpha amylase, catalytic domain Thioredoxin_7 PF13899.6 CBK20530.2 - 5.4e-09 36.1 0.0 8.4e-09 35.5 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like Spec3 PF15795.5 CBK20530.2 - 4.6e-08 33.5 22.2 4.7e-07 30.3 17.2 2.7 2 1 0 2 2 2 1 Ectodermal ciliogenesis protein Thioredoxin PF00085.20 CBK20530.2 - 0.015 15.3 0.0 0.022 14.8 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin FtsK_4TM PF13491.6 CBK20530.2 - 0.033 13.9 6.1 0.052 13.2 6.1 1.2 1 0 0 1 1 1 0 4TM region of DNA translocase FtsK/SpoIIIE Thioredoxin_2 PF13098.6 CBK20530.2 - 0.044 14.2 0.0 0.071 13.6 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin-like domain DUF3810 PF12725.7 CBK20530.2 - 0.16 11.3 0.8 0.2 10.9 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) ICMT PF04140.14 CBK20531.2 - 1.7e-21 76.5 1.0 1.7e-21 76.5 1.0 2.2 2 0 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 CBK20531.2 - 1.3e-09 38.4 2.3 1.3e-09 38.4 2.3 3.2 4 0 0 4 4 4 1 Phospholipid methyltransferase Frag1 PF10277.9 CBK20531.2 - 7.9e-09 35.4 14.3 7.9e-09 35.4 14.3 3.2 3 1 1 4 4 4 1 Frag1/DRAM/Sfk1 family DUF1295 PF06966.12 CBK20531.2 - 0.00031 20.3 1.7 0.00065 19.3 0.7 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF1295) Ada_Zn_binding PF02805.16 CBK20531.2 - 0.0072 16.3 0.0 0.018 15.0 0.0 1.6 1 0 0 1 1 1 1 Metal binding domain of Ada VHP PF02209.19 CBK20531.2 - 0.62 10.2 2.9 0.86 9.7 0.0 2.7 3 0 0 3 3 3 0 Villin headpiece domain DUF3810 PF12725.7 CBK20531.2 - 7.6 5.8 15.3 0.21 10.9 0.6 3.5 3 1 0 3 3 3 0 Protein of unknown function (DUF3810) DAP3 PF10236.9 CBK20532.2 - 3.4e-22 79.0 0.0 6.7e-22 78.1 0.0 1.4 1 1 0 1 1 1 1 Mitochondrial ribosomal death-associated protein 3 AAA_16 PF13191.6 CBK20532.2 - 0.00028 21.3 0.0 0.0012 19.3 0.0 2.1 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 CBK20532.2 - 0.0031 17.8 0.1 0.035 14.4 0.1 2.3 1 1 0 1 1 1 1 AAA domain ATPase_2 PF01637.18 CBK20532.2 - 0.041 13.8 0.0 0.18 11.7 0.0 2.0 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_14 PF13173.6 CBK20532.2 - 0.06 13.4 0.0 0.19 11.7 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 CBK20532.2 - 0.06 13.3 0.0 1.6 8.8 0.0 2.5 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_23 PF13476.6 CBK20532.2 - 0.11 13.0 0.1 0.39 11.2 0.0 1.9 1 1 1 2 2 2 0 AAA domain Actin PF00022.19 CBK20533.2 - 5.5e-94 315.1 0.0 2.6e-93 312.9 0.0 1.7 1 1 0 1 1 1 1 Actin Collagen PF01391.18 CBK20534.2 - 6.9e-31 105.8 107.0 7.5e-10 38.4 27.1 4.2 1 1 3 4 4 4 4 Collagen triple helix repeat (20 copies) ABC_cobalt PF09819.9 CBK20535.2 - 0.035 14.2 2.0 0.047 13.8 2.0 1.3 1 0 0 1 1 1 0 ABC-type cobalt transport system, permease component DUF1673 PF07895.11 CBK20535.2 - 4.4 7.0 15.3 1.3 8.7 3.2 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1673) Ycf1 PF05758.12 CBK20535.2 - 5.9 4.6 9.0 5.9 4.6 9.0 1.1 1 0 0 1 1 1 0 Ycf1 DUF2070 PF09843.9 CBK20535.2 - 9.4 4.4 9.5 11 4.1 9.5 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) DUF4407 PF14362.6 CBK20536.2 - 0.01 15.3 37.2 0.0065 15.9 19.6 2.1 1 1 1 2 2 2 1 Domain of unknown function (DUF4407) XhlA PF10779.9 CBK20536.2 - 0.013 15.7 1.1 0.013 15.7 1.1 4.1 3 2 2 5 5 4 0 Haemolysin XhlA Tropomyosin PF00261.20 CBK20536.2 - 0.43 9.9 53.9 7.1 5.9 25.8 2.8 1 1 1 2 2 2 0 Tropomyosin Tropomyosin_1 PF12718.7 CBK20536.2 - 0.56 10.4 58.1 0.25 11.5 23.9 3.1 1 1 1 2 2 2 0 Tropomyosin like ADIP PF11559.8 CBK20536.2 - 0.97 9.5 54.0 0.19 11.8 17.3 3.2 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding Spc7 PF08317.11 CBK20536.2 - 1.5 7.6 52.7 7.5 5.3 30.9 2.5 1 1 2 3 3 3 0 Spc7 kinetochore protein Laminin_II PF06009.12 CBK20536.2 - 1.7 8.6 26.5 2.4 8.2 10.2 2.6 2 1 0 2 2 2 0 Laminin Domain II Baculo_PEP_C PF04513.12 CBK20536.2 - 2 8.5 12.1 0.84 9.7 3.6 2.7 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Chrome_Resist PF09828.9 CBK20536.2 - 2.8 8.4 9.2 0.43 11.0 1.1 2.8 1 1 2 3 3 3 0 Chromate resistance exported protein HMMR_N PF15905.5 CBK20536.2 - 3 7.2 56.2 3.6 7.0 40.8 2.0 1 1 1 2 2 2 0 Hyaluronan mediated motility receptor N-terminal Mga PF05043.13 CBK20536.2 - 3.1 8.5 18.9 0.18 12.4 7.0 3.5 2 2 2 4 4 4 0 Mga helix-turn-helix domain Mod_r PF07200.13 CBK20536.2 - 3.3 7.8 53.7 0.3 11.2 20.5 3.6 1 1 2 3 3 3 0 Modifier of rudimentary (Mod(r)) protein RPW8 PF05659.11 CBK20536.2 - 4 7.1 19.9 0.37 10.5 6.9 3.3 1 1 1 3 3 3 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 FlaC_arch PF05377.11 CBK20536.2 - 4.5 7.7 32.3 1.4 9.3 7.4 5.0 3 1 2 5 5 5 0 Flagella accessory protein C (FlaC) Filament PF00038.21 CBK20536.2 - 4.8 6.7 53.1 1.9 8.0 25.9 2.3 1 1 1 2 2 2 0 Intermediate filament protein CLZ PF16526.5 CBK20536.2 - 5.9 7.3 45.0 1.8 9.0 5.4 4.0 3 1 1 4 4 4 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF5082 PF16888.5 CBK20536.2 - 7.7 6.8 39.6 4.8 7.5 11.2 3.2 2 1 0 2 2 2 0 Domain of unknown function (DUF5082) ERM PF00769.19 CBK20536.2 - 8.4 6.1 62.4 0.14 11.9 28.4 2.2 1 1 1 2 2 2 0 Ezrin/radixin/moesin family HrpB7 PF09486.10 CBK20536.2 - 8.5 6.7 35.4 9.3 6.6 11.5 3.2 1 1 0 2 2 2 0 Bacterial type III secretion protein (HrpB7) DUF1664 PF07889.12 CBK20536.2 - 9.2 6.3 26.3 0.48 10.5 5.7 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) Nuc_sug_transp PF04142.15 CBK20537.2 - 4.1e-06 26.2 0.4 4.1e-06 26.2 0.4 2.1 2 1 0 2 2 2 1 Nucleotide-sugar transporter PUNUT PF16913.5 CBK20537.2 - 0.00038 19.8 10.2 0.00038 19.8 10.2 1.7 1 1 1 2 2 2 1 Purine nucleobase transmembrane transport EamA PF00892.20 CBK20537.2 - 0.0052 17.0 8.8 0.0052 17.0 8.8 3.6 2 2 0 2 2 2 1 EamA-like transporter family SDH_alpha PF03313.15 CBK20538.2 - 1.9e-78 263.8 5.4 2.2e-78 263.5 5.4 1.1 1 0 0 1 1 1 1 Serine dehydratase alpha chain SDH_beta PF03315.15 CBK20538.2 - 2.7e-17 63.6 0.2 1.1e-08 35.6 0.1 2.5 1 1 1 2 2 2 2 Serine dehydratase beta chain MmgE_PrpD PF03972.14 CBK20538.2 - 0.0055 15.3 3.3 0.0072 14.9 3.3 1.1 1 0 0 1 1 1 1 MmgE/PrpD family HalX PF08663.10 CBK20538.2 - 0.12 12.7 0.6 0.23 11.8 0.6 1.4 1 0 0 1 1 1 0 HalX domain PCRF PF03462.18 CBK20539.2 - 6.7e-45 153.3 0.0 1.3e-44 152.4 0.0 1.5 1 0 0 1 1 1 1 PCRF domain RF-1 PF00472.20 CBK20539.2 - 4.2e-35 120.2 0.2 9.9e-35 119.0 0.2 1.6 1 0 0 1 1 1 1 RF-1 domain C1_1 PF00130.22 CBK20540.2 - 9.6e-07 28.6 4.5 1.7e-06 27.8 4.5 1.4 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) C1_2 PF03107.16 CBK20540.2 - 0.00056 20.2 4.5 0.00094 19.4 4.5 1.4 1 0 0 1 1 1 1 C1 domain DZR PF12773.7 CBK20540.2 - 0.22 11.5 2.8 0.37 10.9 2.8 1.3 1 0 0 1 1 1 0 Double zinc ribbon Pkinase PF00069.25 CBK20541.2 - 7.8e-42 143.4 0.3 1e-41 143.0 0.3 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBK20541.2 - 4.1e-35 121.3 0.1 5.9e-35 120.8 0.1 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 CBK20541.2 - 1.6e-06 27.6 0.0 2.4e-06 27.1 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 CBK20541.2 - 6.5e-06 25.3 0.2 1.4e-05 24.2 0.2 1.6 1 1 0 1 1 1 1 Haspin like kinase domain RIO1 PF01163.22 CBK20541.2 - 0.00068 19.3 0.0 0.0017 18.0 0.0 1.7 1 0 0 1 1 1 1 RIO1 family Pkinase_fungal PF17667.1 CBK20541.2 - 0.0035 16.2 0.0 0.0052 15.6 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 CBK20541.2 - 0.0075 16.2 0.0 0.012 15.5 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family PKD_3 PF16820.5 CBK20541.2 - 0.056 13.2 0.0 0.14 11.9 0.0 1.6 1 0 0 1 1 1 0 PKD-like domain LRR_6 PF13516.6 CBK20542.2 - 1.6e-24 83.8 16.7 0.047 13.7 0.1 12.1 13 0 0 13 13 13 7 Leucine Rich repeat LRR_4 PF12799.7 CBK20542.2 - 5.8e-09 36.1 33.4 0.0012 19.2 3.1 8.7 3 2 7 10 10 10 6 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CBK20542.2 - 1.4e-07 31.1 24.2 0.14 12.0 0.0 9.7 7 2 3 10 10 10 3 Leucine rich repeat LRR_1 PF00560.33 CBK20542.2 - 0.00022 21.3 25.0 15 6.6 0.0 9.8 9 3 0 9 9 9 2 Leucine Rich Repeat F-box PF00646.33 CBK20542.2 - 0.044 13.7 0.1 0.15 12.0 0.1 1.9 1 0 0 1 1 1 0 F-box domain LRR_9 PF14580.6 CBK20542.2 - 0.3 10.6 5.2 0.54 9.7 1.2 3.3 3 2 1 4 4 4 0 Leucine-rich repeat zf-MYND PF01753.18 CBK20543.2 - 1.1e-07 31.8 13.0 1.1e-07 31.8 13.0 2.8 3 0 0 3 3 3 1 MYND finger zf-HIT PF04438.16 CBK20543.2 - 7.4e-05 22.5 8.0 7.4e-05 22.5 8.0 3.1 3 0 0 3 3 3 1 HIT zinc finger C5HCH PF17982.1 CBK20543.2 - 0.022 14.9 6.1 0.022 14.9 6.1 2.7 2 0 0 2 2 2 0 NSD Cys-His rich domain Ldh_1_N PF00056.23 CBK20544.2 - 4.9e-23 81.8 0.0 1.1e-22 80.7 0.0 1.6 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.18 CBK20544.2 - 6.1e-20 71.8 0.0 8.3e-20 71.4 0.0 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain vATP-synt_AC39 PF01992.16 CBK20546.2 - 9.4e-100 334.4 0.1 1.1e-99 334.2 0.1 1.0 1 0 0 1 1 1 1 ATP synthase (C/AC39) subunit HTH_WhiA PF02650.14 CBK20546.2 - 0.16 12.3 0.0 0.41 11.0 0.0 1.7 1 0 0 1 1 1 0 WhiA C-terminal HTH domain S4 PF01479.25 CBK20547.2 - 9.6e-13 47.6 0.0 1.8e-12 46.8 0.0 1.5 1 0 0 1 1 1 1 S4 domain Ribosomal_S4 PF00163.19 CBK20547.2 - 3.9e-06 27.7 1.0 6.1e-06 27.1 1.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain Filament PF00038.21 CBK20549.2 - 1.5e-16 60.9 283.5 2e-05 24.4 50.2 10.7 2 1 9 11 11 11 7 Intermediate filament protein Spc7 PF08317.11 CBK20549.2 - 2e-09 36.8 336.8 0.0047 15.9 28.8 13.3 1 1 13 14 14 13 11 Spc7 kinetochore protein Tropomyosin PF00261.20 CBK20549.2 - 8e-05 22.1 32.0 8e-05 22.1 32.0 12.5 2 2 8 11 11 8 1 Tropomyosin DUF3584 PF12128.8 CBK20549.2 - 0.00016 19.4 115.3 0.00043 18.0 48.8 6.7 1 1 4 6 6 6 3 Protein of unknown function (DUF3584) Med9 PF07544.13 CBK20549.2 - 0.0012 18.8 6.1 0.0012 18.8 6.1 19.8 6 3 13 20 20 13 1 RNA polymerase II transcription mediator complex subunit 9 Atg14 PF10186.9 CBK20549.2 - 0.0013 17.9 22.4 0.0013 17.9 22.4 11.9 2 2 11 13 13 12 4 Vacuolar sorting 38 and autophagy-related subunit 14 DUF4201 PF13870.6 CBK20549.2 - 0.0017 18.2 27.1 0.0017 18.2 27.1 16.7 3 3 9 14 14 13 3 Domain of unknown function (DUF4201) HalX PF08663.10 CBK20549.2 - 0.0033 17.7 4.8 0.0033 17.7 4.8 22.2 6 4 12 22 22 17 1 HalX domain DUF1664 PF07889.12 CBK20549.2 - 0.0041 17.2 3.9 0.0041 17.2 3.9 17.2 3 1 13 19 19 19 5 Protein of unknown function (DUF1664) HrpB7 PF09486.10 CBK20549.2 - 0.0046 17.4 15.7 0.0046 17.4 15.7 15.1 2 1 10 15 15 14 4 Bacterial type III secretion protein (HrpB7) Fib_alpha PF08702.10 CBK20549.2 - 0.0051 17.0 14.3 0.0051 17.0 14.3 15.3 2 1 11 14 14 13 5 Fibrinogen alpha/beta chain family Bacillus_HBL PF05791.11 CBK20549.2 - 0.0064 16.3 4.0 0.0064 16.3 4.0 16.9 5 2 13 18 18 18 6 Bacillus haemolytic enterotoxin (HBL) ATG16 PF08614.11 CBK20549.2 - 0.29 11.3 350.7 0.2 11.8 23.2 15.1 1 1 13 14 14 13 0 Autophagy protein 16 (ATG16) G-patch PF01585.23 CBK20550.2 - 2.3e-10 40.2 1.1 3.9e-10 39.5 1.1 1.4 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 CBK20550.2 - 5.9e-07 29.5 2.3 8.6e-07 29.0 2.1 1.5 1 1 0 1 1 1 1 G-patch domain GCFC PF07842.12 CBK20551.2 - 2.1e-12 47.3 3.8 3.1e-12 46.7 0.1 2.9 2 2 0 2 2 2 1 GC-rich sequence DNA-binding factor-like protein Pox_H7 PF04787.12 CBK20551.2 - 0.013 16.0 0.1 0.51 10.9 0.0 2.4 2 0 0 2 2 2 0 Late protein H7 DUF2098 PF09871.9 CBK20551.2 - 0.16 12.3 6.1 0.052 13.9 1.5 2.4 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2098) DUF3993 PF13158.6 CBK20551.2 - 1.1 9.5 4.4 2.5 8.3 0.4 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3993) Ribosomal_L18A PF01775.17 CBK20552.2 - 2e-41 140.9 0.3 2.9e-41 140.4 0.3 1.2 1 0 0 1 1 1 1 Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A Ribosomal_S5_C PF03719.15 CBK20553.2 - 6e-26 89.7 0.0 9.9e-26 89.0 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain Ribosomal_S5 PF00333.20 CBK20553.2 - 2.9e-25 88.0 2.1 6e-25 87.0 2.1 1.5 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain PRR20 PF15708.5 CBK20553.2 - 0.049 13.5 3.2 0.064 13.2 1.7 1.8 2 0 0 2 2 2 0 Proline-rich protein family 20 DUF4919 PF16266.5 CBK20554.2 - 0.0015 18.5 0.0 0.4 10.6 0.0 2.5 2 0 0 2 2 2 2 Domain of unknown function (DUF4919) TPR_19 PF14559.6 CBK20554.2 - 0.074 13.6 1.1 34 5.1 0.0 3.9 3 1 1 5 5 5 0 Tetratricopeptide repeat Coatomer_E PF04733.14 CBK20554.2 - 0.086 12.2 0.6 1.7 8.0 0.2 2.4 2 1 1 3 3 3 0 Coatomer epsilon subunit HSP70 PF00012.20 CBK20555.2 - 8.1e-100 334.7 0.0 1e-99 334.4 0.0 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 CBK20555.2 - 7.3e-19 67.7 0.1 5.3e-17 61.6 0.2 2.7 2 1 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.16 CBK20555.2 - 0.0083 15.9 0.1 0.017 14.8 0.1 1.6 1 1 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain Ketoacyl-synt_C PF02801.22 CBK20555.2 - 0.17 11.9 0.0 11 6.0 0.0 2.3 2 0 0 2 2 2 0 Beta-ketoacyl synthase, C-terminal domain Peptidase_C1 PF00112.23 CBK20556.2 - 7.9e-67 225.5 0.1 1.1e-66 225.1 0.1 1.2 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 CBK20556.2 - 4.2e-09 36.7 0.7 7.9e-09 35.8 0.7 1.5 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.15 CBK20556.2 - 1.2e-06 27.6 0.7 0.012 14.4 0.4 2.1 2 0 0 2 2 2 2 Peptidase C1-like family zf-RING_4 PF14570.6 CBK20557.2 - 2.9e-14 52.6 13.2 9.2e-14 51.0 13.2 1.9 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain RRM_1 PF00076.22 CBK20557.2 - 3.6e-08 33.1 0.0 5.8e-08 32.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-C3HC4_3 PF13920.6 CBK20557.2 - 2.4e-05 24.1 12.8 8.7e-05 22.3 12.8 2.0 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) RRM_occluded PF16842.5 CBK20557.2 - 0.00057 19.7 0.0 0.0015 18.4 0.0 1.7 1 1 0 1 1 1 1 Occluded RNA-recognition motif Torus PF16131.5 CBK20557.2 - 0.0022 18.7 4.5 0.0051 17.5 4.5 1.6 1 0 0 1 1 1 1 Torus domain zf-CCCH_2 PF14608.6 CBK20557.2 - 0.0027 18.1 3.0 0.0049 17.3 1.2 2.6 2 0 0 2 2 2 1 RNA-binding, Nab2-type zinc finger zf-UDP PF14569.6 CBK20557.2 - 0.0044 17.1 5.3 0.011 15.8 5.3 1.7 1 0 0 1 1 1 1 Zinc-binding RING-finger Nup35_RRM_2 PF14605.6 CBK20557.2 - 0.08 13.0 0.1 0.61 10.1 0.0 2.2 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif zf-C3HC4_2 PF13923.6 CBK20557.2 - 0.36 10.7 19.8 0.082 12.8 16.0 2.0 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) DUF2034 PF10356.9 CBK20558.2 - 1.4e-12 47.4 0.3 8.2e-08 31.9 0.0 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF2034) Mrr_cat PF04471.12 CBK20558.2 - 4e-07 30.0 0.0 5.8e-07 29.5 0.0 1.1 1 0 0 1 1 1 1 Restriction endonuclease Mrr_cat_2 PF13156.6 CBK20558.2 - 0.04 13.8 0.1 0.79 9.6 0.0 2.0 1 1 1 2 2 2 0 Restriction endonuclease ATP-synt_ab PF00006.25 CBK20559.2 - 1.2e-65 221.1 0.0 1.7e-65 220.7 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 CBK20559.2 - 6.3e-10 39.4 0.4 1.1e-09 38.6 0.4 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain HAS-barrel PF09378.10 CBK20559.2 - 0.028 14.6 0.1 0.066 13.4 0.1 1.7 1 0 0 1 1 1 0 HAS barrel domain Pkinase PF00069.25 CBK20560.2 - 1.3e-48 165.7 0.0 1.7e-48 165.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBK20560.2 - 9.7e-30 103.7 0.0 1.2e-29 103.4 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CBK20560.2 - 3.7e-08 33.0 0.0 5.5e-08 32.5 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 CBK20560.2 - 1.3e-06 27.4 0.0 1.7e-06 27.1 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 CBK20560.2 - 0.02 14.8 0.2 0.074 13.0 0.0 1.8 2 0 0 2 2 2 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 CBK20560.2 - 0.04 12.8 0.0 0.052 12.5 0.0 1.1 1 0 0 1 1 1 0 Haspin like kinase domain PBD PF00786.28 CBK20561.2 - 7.7e-06 26.2 0.0 1.6e-05 25.1 0.0 1.6 1 0 0 1 1 1 1 P21-Rho-binding domain Pkinase PF00069.25 CBK20561.2 - 3.8e-05 23.2 1.8 0.0002 20.8 1.2 2.3 2 1 0 2 2 2 1 Protein kinase domain SHQ1 PF04925.15 CBK20561.2 - 0.0065 16.1 0.2 0.046 13.3 0.0 2.0 2 0 0 2 2 2 1 SHQ1 protein E1-E2_ATPase PF00122.20 CBK20563.2 - 5.4e-18 65.2 0.0 5.7e-17 61.8 0.0 2.4 1 1 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.26 CBK20563.2 - 4.3e-16 59.8 0.0 1.4e-08 35.3 0.0 2.4 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 CBK20563.2 - 4.2e-06 26.7 0.0 9.6e-06 25.6 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_C PF00689.21 CBK20563.2 - 7.8e-05 22.5 9.2 7.8e-05 22.5 9.2 2.4 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Glycos_transf_2 PF00535.26 CBK20564.2 - 2.3e-16 60.1 0.0 3.5e-16 59.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 CBK20564.2 - 9.4e-06 25.7 0.0 2.3e-05 24.4 0.0 1.6 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 CBK20564.2 - 0.092 12.2 0.0 0.15 11.5 0.0 1.3 1 0 0 1 1 1 0 Glycosyltransferase like family 2 MORN PF02493.20 CBK20565.2 - 7.9e-09 34.9 83.4 0.02 14.8 0.5 15.2 14 0 0 14 14 14 8 MORN repeat ABC2_membrane PF01061.24 CBK20566.2 - 1.8e-39 135.4 16.7 2.2e-39 135.0 16.7 1.1 1 0 0 1 1 1 1 ABC-2 type transporter ABC2_membrane_3 PF12698.7 CBK20566.2 - 0.0015 17.7 11.6 0.0015 17.7 11.6 2.0 1 1 1 2 2 2 1 ABC-2 family transporter protein s48_45 PF07422.13 CBK20566.2 - 0.2 12.2 2.4 0.41 11.2 2.4 1.5 1 0 0 1 1 1 0 Sexual stage antigen s48/45 domain NPV_P10 PF05531.12 CBK20567.2 - 0.31 11.5 16.4 0.21 12.1 1.0 3.8 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Baculo_PEP_C PF04513.12 CBK20567.2 - 2 8.5 18.6 5.5 7.0 1.9 3.1 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Ion_trans_2 PF07885.16 CBK20569.2 - 7.1e-06 25.9 0.8 2.3e-05 24.2 0.8 1.9 1 0 0 1 1 1 1 Ion channel BK_channel_a PF03493.18 CBK20569.2 - 8.8e-05 22.6 0.0 0.00037 20.6 0.0 1.9 1 1 0 1 1 1 1 Calcium-activated BK potassium channel alpha subunit Ion_trans PF00520.31 CBK20569.2 - 0.065 12.4 9.1 0.35 10.1 0.0 2.2 2 0 0 2 2 2 0 Ion transport protein SBDS PF01172.18 CBK20570.2 - 4.2e-27 94.1 0.1 8.1e-27 93.1 0.1 1.5 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein SBDS_C PF09377.10 CBK20570.2 - 4e-24 84.8 1.9 7.2e-24 84.0 1.9 1.4 1 0 0 1 1 1 1 SBDS protein C-terminal domain zf-C2H2_jaz PF12171.8 CBK20570.2 - 0.0038 17.5 1.6 0.0087 16.3 1.6 1.7 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding Ras PF00071.22 CBK20571.2 - 3e-48 163.5 0.1 4.1e-48 163.1 0.1 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CBK20571.2 - 3.4e-30 104.7 0.0 7.1e-30 103.7 0.0 1.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CBK20571.2 - 9e-16 57.8 0.3 3e-15 56.1 0.3 1.7 1 1 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 CBK20571.2 - 2e-06 27.8 0.8 0.00039 20.4 0.0 2.1 1 1 1 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 CBK20571.2 - 2.4e-06 27.3 0.1 7.5e-06 25.6 0.1 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 CBK20571.2 - 0.00055 19.4 0.1 0.0016 17.9 0.0 1.7 1 1 1 2 2 2 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 CBK20571.2 - 0.00073 19.6 0.0 0.0011 19.0 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 CBK20571.2 - 0.0074 15.8 0.2 0.072 12.6 0.2 2.1 1 1 0 1 1 1 1 Ferrous iron transport protein B Chordopox_A33R PF05966.12 CBK20571.2 - 0.011 15.0 0.1 0.024 13.9 0.1 1.5 1 1 0 1 1 1 0 Chordopoxvirus A33R protein Gtr1_RagA PF04670.12 CBK20571.2 - 0.062 12.6 0.0 0.091 12.1 0.0 1.4 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region INSC_LBD PF16748.5 CBK20571.2 - 0.062 12.8 0.0 0.12 11.8 0.0 1.5 1 0 0 1 1 1 0 Inscuteable LGN-binding domain ABC_tran PF00005.27 CBK20571.2 - 0.15 12.6 0.0 0.42 11.1 0.0 1.8 1 1 0 1 1 1 0 ABC transporter He_PIG PF05345.12 CBK20572.2 - 0.0028 17.8 0.2 0.023 14.9 0.1 2.6 2 0 0 2 2 2 1 Putative Ig domain DUF4448 PF14610.6 CBK20572.2 - 0.038 13.8 0.1 0.64 9.8 0.1 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF4448) RIFIN PF02009.16 CBK20572.2 - 0.16 11.8 0.5 0.25 11.2 0.5 1.2 1 0 0 1 1 1 0 Rifin TMEM154 PF15102.6 CBK20572.2 - 0.19 11.6 0.0 0.41 10.5 0.0 1.6 1 0 0 1 1 1 0 TMEM154 protein family HSP70 PF00012.20 CBK20573.2 - 2.2e-67 227.6 0.0 3.8e-67 226.9 0.0 1.3 1 1 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 CBK20573.2 - 3.6e-10 39.2 0.0 1.3e-08 34.0 0.0 2.3 2 0 0 2 2 2 2 MreB/Mbl protein TCR PF03638.15 CBK20575.2 - 6e-23 80.9 57.6 2.4e-11 43.7 26.9 2.7 2 0 0 2 2 2 2 Tesmin/TSO1-like CXC domain, cysteine-rich domain SWIB PF02201.18 CBK20575.2 - 1.1e-12 47.7 0.1 2.6e-12 46.4 0.1 1.7 1 0 0 1 1 1 1 SWIB/MDM2 domain MSL2-CXC PF16682.5 CBK20575.2 - 3.7 7.7 47.0 3.6 7.8 17.4 2.8 2 1 0 2 2 2 0 CXC domain of E3 ubiquitin-protein ligase MSL2 SWIB PF02201.18 CBK20576.2 - 6.7e-28 96.4 0.0 8.2e-28 96.1 0.0 1.1 1 0 0 1 1 1 1 SWIB/MDM2 domain Ribosomal_S17 PF00366.20 CBK20577.2 - 1.5e-24 85.8 0.5 1.9e-24 85.5 0.5 1.1 1 0 0 1 1 1 1 Ribosomal protein S17 NUDIX PF00293.28 CBK20578.2 - 8.8e-11 42.0 0.0 8.8e-11 42.0 0.0 1.1 1 0 0 1 1 1 1 NUDIX domain EF-hand_1 PF00036.32 CBK20579.2 - 1.2e-13 49.6 2.1 7.9e-07 28.2 0.3 3.9 4 0 0 4 4 4 2 EF hand EF-hand_6 PF13405.6 CBK20579.2 - 2.2e-13 49.0 1.9 7.3e-06 25.5 0.1 3.7 4 0 0 4 4 4 3 EF-hand domain EF-hand_8 PF13833.6 CBK20579.2 - 2.5e-11 43.3 0.6 2.3e-07 30.6 0.0 2.5 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_7 PF13499.6 CBK20579.2 - 3.3e-10 40.3 0.1 0.00062 20.2 0.0 2.9 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.6 CBK20579.2 - 2e-07 30.2 2.8 5.1e-05 22.6 0.9 3.9 4 0 0 4 4 4 1 EF hand Caleosin PF05042.13 CBK20579.2 - 0.013 15.5 0.2 0.29 11.1 0.1 2.2 1 1 1 2 2 2 0 Caleosin related protein zf-MIZ PF02891.20 CBK20579.2 - 0.027 14.2 1.9 0.059 13.1 0.4 2.1 2 0 0 2 2 2 0 MIZ/SP-RING zinc finger XPA_N PF01286.18 CBK20579.2 - 0.77 9.9 3.0 0.39 10.8 0.5 1.8 2 0 0 2 2 2 0 XPA protein N-terminal Orn_Arg_deC_N PF02784.16 CBK20580.2 - 1.3e-39 136.1 0.0 1.8e-39 135.6 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.22 CBK20580.2 - 3.7e-10 39.9 0.0 4.4e-10 39.7 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain PseudoU_synth_1 PF01416.20 CBK20581.2 - 2.7e-05 24.6 0.0 8.3e-05 23.0 0.0 1.8 2 1 0 2 2 2 1 tRNA pseudouridine synthase DUF2344 PF10105.9 CBK20581.2 - 0.019 14.8 0.0 0.03 14.2 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2344) PI_PP_C PF18365.1 CBK20582.2 - 0.022 14.7 0.2 0.06 13.3 0.2 1.6 1 1 1 2 2 2 0 Phosphoinositide phosphatase C-terminal domain Ribonuc_red_lgN PF00317.21 CBK20583.2 - 0.035 14.1 0.1 0.061 13.3 0.1 1.3 1 0 0 1 1 1 0 Ribonucleotide reductase, all-alpha domain DUF4647 PF15504.6 CBK20583.2 - 0.043 12.9 3.5 0.048 12.8 3.5 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4647) Rho_Binding PF08912.11 CBK20583.2 - 0.13 13.1 4.6 1.9 9.4 4.0 2.5 1 1 0 1 1 1 0 Rho Binding Ribosomal_60s PF00428.19 CBK20584.2 - 3.9e-19 69.0 11.0 5.5e-19 68.5 11.0 1.2 1 0 0 1 1 1 1 60s Acidic ribosomal protein HEXIM PF15313.6 CBK20584.2 - 0.0063 16.7 0.0 0.0083 16.3 0.0 1.1 1 0 0 1 1 1 1 Hexamethylene bis-acetamide-inducible protein Cytomega_UL84 PF06284.11 CBK20584.2 - 2.1 6.7 3.2 2.3 6.6 3.2 1.1 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein DAP3 PF10236.9 CBK20585.2 - 3.4e-22 79.0 0.0 6.7e-22 78.1 0.0 1.4 1 1 0 1 1 1 1 Mitochondrial ribosomal death-associated protein 3 AAA_16 PF13191.6 CBK20585.2 - 0.00028 21.3 0.0 0.0012 19.3 0.0 2.1 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 CBK20585.2 - 0.0031 17.8 0.1 0.035 14.4 0.1 2.3 1 1 0 1 1 1 1 AAA domain ATPase_2 PF01637.18 CBK20585.2 - 0.041 13.8 0.0 0.18 11.7 0.0 2.0 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_14 PF13173.6 CBK20585.2 - 0.06 13.4 0.0 0.19 11.7 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 CBK20585.2 - 0.06 13.3 0.0 1.6 8.8 0.0 2.5 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_23 PF13476.6 CBK20585.2 - 0.11 13.0 0.1 0.39 11.2 0.0 1.9 1 1 1 2 2 2 0 AAA domain Aldo_ket_red PF00248.21 CBK20586.2 - 4.1e-43 147.7 0.0 6.1e-43 147.1 0.0 1.2 1 0 0 1 1 1 1 Aldo/keto reductase family Terminase_2 PF03592.16 CBK20586.2 - 0.11 13.0 0.1 0.21 12.0 0.1 1.4 1 0 0 1 1 1 0 Terminase small subunit SBDS PF01172.18 CBK20587.2 - 3.2e-12 46.4 0.4 6.4e-12 45.4 0.4 1.5 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein SBDS_C PF09377.10 CBK20587.2 - 1.9e-09 37.5 0.4 3e-09 36.9 0.4 1.3 1 0 0 1 1 1 1 SBDS protein C-terminal domain PPP4R2 PF09184.11 CBK20587.2 - 0.06 12.9 0.5 0.11 12.0 0.2 1.5 1 1 1 2 2 2 0 PPP4R2 Band_7 PF01145.25 CBK20589.2 - 1.1e-36 126.5 2.5 1.1e-36 126.5 2.5 2.1 2 1 0 2 2 2 1 SPFH domain / Band 7 family Band_7_1 PF13421.6 CBK20589.2 - 0.00042 20.1 0.2 0.00074 19.3 0.2 1.6 1 1 0 1 1 1 1 SPFH domain-Band 7 family CBS PF00571.28 CBK20590.2 - 1.3e-15 57.6 0.3 0.00093 19.6 0.0 4.7 4 1 0 4 4 4 4 CBS domain AAA_12 PF13087.6 CBK20591.2 - 8.9e-59 198.5 0.1 1.1e-57 194.9 0.0 2.5 2 1 0 2 2 2 1 AAA domain AAA_11 PF13086.6 CBK20591.2 - 5.5e-45 154.2 6.9 2.3e-26 93.2 0.2 3.0 2 1 1 3 3 3 2 AAA domain UPF1_Zn_bind PF09416.10 CBK20591.2 - 7.7e-36 123.4 6.1 1.8e-35 122.2 6.1 1.7 1 0 0 1 1 1 1 RNA helicase (UPF2 interacting domain) AAA_30 PF13604.6 CBK20591.2 - 1.2e-14 54.4 0.0 2.3e-13 50.3 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 CBK20591.2 - 1.5e-09 38.4 0.0 4.8e-09 36.7 0.0 1.9 1 1 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 CBK20591.2 - 1.1e-07 31.8 0.0 0.0073 16.1 0.0 3.1 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase UvrD-helicase PF00580.21 CBK20591.2 - 0.00086 18.9 0.9 0.15 11.6 0.0 3.1 3 0 0 3 3 3 1 UvrD/REP helicase N-terminal domain PhoH PF02562.16 CBK20591.2 - 0.05 13.1 0.0 0.38 10.2 0.0 2.4 2 0 0 2 2 2 0 PhoH-like protein MLVIN_C PF18697.1 CBK20591.2 - 0.091 12.9 0.0 0.27 11.4 0.0 1.7 1 0 0 1 1 1 0 Murine leukemia virus (MLV) integrase (IN) C-terminal domain Prok-RING_2 PF14445.6 CBK20591.2 - 0.36 11.0 3.0 1.1 9.4 3.0 1.8 1 0 0 1 1 1 0 Prokaryotic RING finger family 2 Zf_RING PF16744.5 CBK20591.2 - 0.46 10.6 5.2 0.29 11.3 1.6 2.4 2 0 0 2 2 2 0 KIAA1045 RING finger PHD_Oberon PF07227.11 CBK20591.2 - 4.9 7.0 9.3 2.5 8.0 4.7 2.8 3 0 0 3 3 3 0 PHD - plant homeodomain finger protein AAA PF00004.29 CBK20592.2 - 1.2e-43 148.7 0.2 5.4e-43 146.6 0.0 2.2 3 0 0 3 3 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CBK20592.2 - 1.9e-10 40.4 0.2 4.4e-10 39.2 0.2 1.7 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 CBK20592.2 - 1.4e-06 28.4 0.0 5.7e-06 26.4 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 CBK20592.2 - 3.3e-06 27.6 0.1 0.00012 22.5 0.0 2.5 1 1 1 2 2 2 1 AAA ATPase domain AAA_2 PF07724.14 CBK20592.2 - 1.9e-05 24.8 0.1 5.1e-05 23.5 0.0 1.7 2 0 0 2 2 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 CBK20592.2 - 0.00012 22.4 0.2 0.011 16.0 0.0 2.5 1 1 1 2 2 2 1 AAA domain RuvB_N PF05496.12 CBK20592.2 - 0.00015 21.6 0.0 0.00033 20.4 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain TIP49 PF06068.13 CBK20592.2 - 0.0011 18.2 0.5 0.002 17.4 0.0 1.6 2 0 0 2 2 1 1 TIP49 P-loop domain DivIC PF04977.15 CBK20592.2 - 0.0013 18.5 2.7 0.003 17.3 2.7 1.6 1 0 0 1 1 1 1 Septum formation initiator AAA_33 PF13671.6 CBK20592.2 - 0.0015 18.7 1.1 0.0025 18.0 0.0 1.9 2 0 0 2 2 1 1 AAA domain Prot_ATP_ID_OB PF16450.5 CBK20592.2 - 0.0018 18.2 0.0 0.0055 16.6 0.0 1.8 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain TMF_TATA_bd PF12325.8 CBK20592.2 - 0.0032 17.7 1.5 0.0098 16.1 1.5 1.8 1 0 0 1 1 1 1 TATA element modulatory factor 1 TATA binding IstB_IS21 PF01695.17 CBK20592.2 - 0.0037 17.0 0.0 0.0072 16.1 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_18 PF13238.6 CBK20592.2 - 0.0047 17.5 0.1 0.015 15.9 0.0 2.0 2 0 0 2 2 1 1 AAA domain AAA_7 PF12775.7 CBK20592.2 - 0.0065 16.0 0.0 0.013 15.0 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region PhoH PF02562.16 CBK20592.2 - 0.0066 15.9 0.0 0.13 11.6 0.0 2.3 2 0 0 2 2 2 1 PhoH-like protein AAA_28 PF13521.6 CBK20592.2 - 0.011 15.9 0.8 0.039 14.2 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.6 CBK20592.2 - 0.012 15.7 0.0 0.025 14.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.6 CBK20592.2 - 0.012 15.4 0.9 0.29 10.9 0.0 2.3 2 0 0 2 2 2 0 AAA domain Mg_chelatase PF01078.21 CBK20592.2 - 0.013 14.9 0.1 0.028 13.8 0.1 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 CBK20592.2 - 0.014 15.2 0.0 0.031 14.1 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) APG6_N PF17675.1 CBK20592.2 - 0.023 15.2 2.6 0.057 13.9 2.6 1.6 1 0 0 1 1 1 0 Apg6 coiled-coil region AAA_24 PF13479.6 CBK20592.2 - 0.024 14.3 0.0 0.066 12.9 0.0 1.9 2 0 0 2 2 1 0 AAA domain Zeta_toxin PF06414.12 CBK20592.2 - 0.025 13.9 1.4 0.083 12.2 0.0 2.2 2 0 0 2 2 2 0 Zeta toxin ATPase PF06745.13 CBK20592.2 - 0.028 13.7 0.3 0.19 11.1 0.0 2.4 3 0 0 3 3 3 0 KaiC UPF0242 PF06785.11 CBK20592.2 - 0.03 14.5 2.9 0.053 13.6 2.9 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus RNA_helicase PF00910.22 CBK20592.2 - 0.032 14.6 0.0 0.068 13.6 0.0 1.6 1 0 0 1 1 1 0 RNA helicase TsaE PF02367.17 CBK20592.2 - 0.032 14.2 0.0 0.064 13.3 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Sigma54_activat PF00158.26 CBK20592.2 - 0.035 13.8 0.0 0.11 12.1 0.0 1.8 2 0 0 2 2 1 0 Sigma-54 interaction domain NACHT PF05729.12 CBK20592.2 - 0.036 14.0 0.0 0.67 9.8 0.0 2.3 1 1 0 2 2 2 0 NACHT domain Parvo_NS1 PF01057.17 CBK20592.2 - 0.045 12.8 0.0 0.093 11.8 0.0 1.4 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 DUF815 PF05673.13 CBK20592.2 - 0.046 12.9 0.0 0.083 12.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_25 PF13481.6 CBK20592.2 - 0.062 12.9 0.0 0.19 11.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain Nuc_deoxyrib_tr PF05014.15 CBK20592.2 - 0.089 12.8 0.0 0.19 11.7 0.0 1.6 1 0 0 1 1 1 0 Nucleoside 2-deoxyribosyltransferase APT PF03440.14 CBK20592.2 - 0.095 12.7 0.0 0.25 11.4 0.0 1.7 1 0 0 1 1 1 0 Aerolysin/Pertussis toxin (APT) domain AAA_13 PF13166.6 CBK20592.2 - 0.11 11.2 0.2 3.7 6.1 0.1 2.1 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 CBK20592.2 - 0.17 12.4 0.3 1.1 9.7 0.0 2.3 2 0 0 2 2 2 0 ABC transporter DUF2968 PF11180.8 CBK20592.2 - 0.18 11.4 3.0 0.34 10.5 3.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) AAA_17 PF13207.6 CBK20592.2 - 0.26 11.7 2.0 0.58 10.6 0.0 2.4 2 1 0 2 2 2 0 AAA domain FlaC_arch PF05377.11 CBK20592.2 - 0.3 11.5 4.4 0.64 10.5 3.3 2.1 2 0 0 2 2 1 0 Flagella accessory protein C (FlaC) MnmE_helical PF12631.7 CBK20593.2 - 0.0084 16.3 0.2 0.014 15.6 0.2 1.3 1 0 0 1 1 1 1 MnmE helical domain Baculo_PEP_C PF04513.12 CBK20593.2 - 0.01 15.9 0.6 0.05 13.6 0.7 1.9 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Bap31_Bap29_C PF18035.1 CBK20593.2 - 0.013 15.5 2.1 0.054 13.5 0.3 2.4 2 0 0 2 2 2 0 Bap31/Bap29 cytoplasmic coiled-coil domain JAKMIP_CC3 PF16034.5 CBK20593.2 - 0.027 14.4 0.2 0.034 14.1 0.2 1.3 1 0 0 1 1 1 0 JAKMIP CC3 domain DUF724 PF05266.14 CBK20593.2 - 0.029 14.2 3.2 0.053 13.4 3.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF724) Spc7 PF08317.11 CBK20593.2 - 0.056 12.3 7.1 0.026 13.4 4.7 1.5 2 0 0 2 2 2 0 Spc7 kinetochore protein FapA PF03961.13 CBK20593.2 - 0.075 11.6 2.1 0.13 10.8 2.1 1.3 1 0 0 1 1 1 0 Flagellar Assembly Protein A COG5 PF10392.9 CBK20593.2 - 0.16 12.2 6.6 2.8 8.1 2.2 2.9 2 1 1 3 3 3 0 Golgi transport complex subunit 5 Atg14 PF10186.9 CBK20593.2 - 0.23 10.5 4.2 0.39 9.8 4.2 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF948 PF06103.11 CBK20593.2 - 0.33 11.2 2.4 6.3 7.1 0.2 2.5 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) Mod_r PF07200.13 CBK20593.2 - 0.61 10.2 7.1 0.17 12.0 3.4 2.0 2 1 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein YlqD PF11068.8 CBK20593.2 - 1.1 9.7 6.2 0.23 11.9 2.5 1.7 2 0 0 2 2 2 0 YlqD protein DivIC PF04977.15 CBK20593.2 - 1.1 9.0 5.2 10 6.0 1.9 2.6 1 1 1 2 2 2 0 Septum formation initiator XhlA PF10779.9 CBK20593.2 - 5.2 7.4 6.6 4 7.7 1.1 2.7 1 1 1 2 2 2 0 Haemolysin XhlA YabA PF06156.13 CBK20593.2 - 5.3 7.7 7.0 6.7 7.4 3.6 2.6 2 1 0 2 2 1 0 Initiation control protein YabA Snapin_Pallidin PF14712.6 CBK20593.2 - 6.1 7.3 8.1 0.72 10.3 2.2 2.3 2 1 1 3 3 3 0 Snapin/Pallidin bZIP_2 PF07716.15 CBK20593.2 - 6.2 7.0 5.6 4.4 7.5 2.2 2.2 2 0 0 2 2 2 0 Basic region leucine zipper Aldo_ket_red PF00248.21 CBK20594.2 - 3.7e-06 26.4 0.0 4.3e-06 26.1 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family TT_ORF1 PF02956.14 CBK20594.2 - 6.5 5.3 7.0 8 5.0 7.0 1.1 1 0 0 1 1 1 0 TT viral orf 1 Pkinase PF00069.25 CBK20595.2 - 1.9e-63 214.3 0.0 3.1e-63 213.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBK20595.2 - 3.3e-41 141.3 0.0 5e-41 140.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.28 CBK20595.2 - 1.9e-07 31.3 0.2 1.3e-06 28.6 0.0 2.2 2 0 0 2 2 2 1 P21-Rho-binding domain Kinase-like PF14531.6 CBK20595.2 - 1.1e-05 24.9 0.0 0.001 18.5 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Pkinase_fungal PF17667.1 CBK20595.2 - 1.8e-05 23.7 0.0 4.5e-05 22.4 0.0 1.6 2 0 0 2 2 2 1 Fungal protein kinase Haspin_kinase PF12330.8 CBK20595.2 - 0.00015 20.9 2.1 0.065 12.2 0.0 2.1 2 0 0 2 2 2 2 Haspin like kinase domain APH PF01636.23 CBK20595.2 - 0.0095 15.9 0.0 0.019 14.9 0.0 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 CBK20595.2 - 0.017 14.2 0.2 0.028 13.5 0.2 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 MMACHC PF16690.5 CBK20596.2 - 4.4e-11 42.8 0.4 4.3e-10 39.6 0.4 1.9 1 1 0 1 1 1 1 Methylmalonic aciduria and homocystinuria type C family KH_1 PF00013.29 CBK20597.2 - 4.4e-10 39.2 2.1 5.3e-10 39.0 2.1 1.0 1 0 0 1 1 1 1 KH domain KH_2 PF07650.17 CBK20597.2 - 0.033 14.0 0.2 0.05 13.4 0.2 1.4 1 1 0 1 1 1 0 KH domain Fuseless PF15993.5 CBK20598.2 - 0.035 13.3 0.0 0.046 12.9 0.0 1.1 1 0 0 1 1 1 0 Fuseless LRR19-TM PF15176.6 CBK20598.2 - 0.069 13.1 0.0 0.12 12.4 0.0 1.4 1 0 0 1 1 1 0 Leucine-rich repeat family 19 TM domain WD40 PF00400.32 CBK20599.2 - 4.7e-06 27.2 0.5 0.0037 18.1 0.2 2.7 2 0 0 2 2 2 2 WD domain, G-beta repeat WD40_like PF17005.5 CBK20599.2 - 0.0033 16.8 2.7 0.014 14.8 2.7 1.8 1 1 0 1 1 1 1 WD40-like domain Nup160 PF11715.8 CBK20599.2 - 0.017 13.8 0.1 0.053 12.2 0.0 1.7 2 0 0 2 2 2 0 Nucleoporin Nup120/160 NTR PF01759.21 CBK20599.2 - 0.028 14.2 0.0 0.071 12.9 0.0 1.7 1 1 1 2 2 2 0 UNC-6/NTR/C345C module Ribosomal_S9 PF00380.19 CBK20601.2 - 1.3e-29 103.2 0.1 1.4e-29 103.0 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S9/S16 LapA_dom PF06305.11 CBK20602.2 - 0.049 13.5 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain AICARFT_IMPCHas PF01808.18 CBK20603.2 - 3.2e-83 279.6 0.1 4.3e-83 279.2 0.1 1.2 1 0 0 1 1 1 1 AICARFT/IMPCHase bienzyme MGS PF02142.22 CBK20603.2 - 8.7e-27 93.2 0.0 2.5e-26 91.7 0.0 1.9 1 0 0 1 1 1 1 MGS-like domain WD40 PF00400.32 CBK20604.2 - 2.2e-10 40.9 14.1 6.2e-05 23.7 0.7 5.1 5 0 0 5 5 5 3 WD domain, G-beta repeat WD40_like PF17005.5 CBK20604.2 - 0.00013 21.4 0.4 0.0003 20.2 0.4 1.6 1 1 0 1 1 1 1 WD40-like domain tRNA-synt_2 PF00152.20 CBK20605.2 - 1.2e-78 264.4 0.1 2.8e-78 263.2 0.1 1.5 1 1 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA-synt_2d PF01409.20 CBK20605.2 - 0.0013 18.3 0.4 0.25 10.8 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) YhfZ_C PF14503.6 CBK20605.2 - 0.19 11.3 0.0 0.3 10.6 0.0 1.2 1 0 0 1 1 1 0 YhfZ C-terminal domain UQ_con PF00179.26 CBK20606.2 - 4.5e-35 120.3 0.0 9.6e-35 119.3 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Hamartin PF04388.12 CBK20606.2 - 0.033 12.9 10.7 0.042 12.5 10.7 1.0 1 0 0 1 1 1 0 Hamartin protein Membralin PF09746.9 CBK20606.2 - 0.057 12.5 2.4 0.063 12.3 2.4 1.1 1 0 0 1 1 1 0 Tumour-associated protein Presenilin PF01080.17 CBK20606.2 - 0.28 9.9 12.4 0.34 9.6 12.4 1.1 1 0 0 1 1 1 0 Presenilin SID-1_RNA_chan PF13965.6 CBK20606.2 - 0.45 8.9 2.1 0.5 8.7 2.1 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Neur_chan_memb PF02932.16 CBK20606.2 - 0.46 10.5 2.3 0.59 10.1 2.3 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region SLC12 PF03522.15 CBK20606.2 - 1.3 8.0 11.6 1.7 7.6 11.6 1.1 1 0 0 1 1 1 0 Solute carrier family 12 FAM60A PF15396.6 CBK20606.2 - 1.3 9.0 12.8 1.8 8.5 12.8 1.2 1 0 0 1 1 1 0 Protein Family FAM60A Atrophin-1 PF03154.15 CBK20606.2 - 3 6.0 13.8 4 5.6 13.8 1.0 1 0 0 1 1 1 0 Atrophin-1 family Hydin_ADK PF17213.3 CBK20606.2 - 3.1 8.0 8.8 4.4 7.5 8.8 1.1 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain NPR3 PF03666.13 CBK20606.2 - 4.2 6.0 16.1 5.3 5.7 16.1 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Zip PF02535.22 CBK20606.2 - 4.7 6.3 7.7 6.2 5.9 7.7 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter TFIIF_alpha PF05793.12 CBK20606.2 - 8.9 4.8 30.2 12 4.4 30.2 1.0 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Alpha-amylase PF00128.24 CBK20608.2 - 0.0086 15.7 0.0 0.01 15.4 0.0 1.1 1 0 0 1 1 1 1 Alpha amylase, catalytic domain Amidohydro_3 PF07969.11 CBK20609.2 - 4.7e-06 26.3 0.3 1.9e-05 24.4 0.3 1.9 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_1 PF01979.20 CBK20609.2 - 0.00056 19.3 0.0 0.00089 18.7 0.0 1.5 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_1 PF01979.20 CBK20610.2 - 2.2e-11 43.7 0.0 3.3e-11 43.1 0.0 1.4 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 CBK20610.2 - 7.7e-11 42.1 0.0 9.1e-11 41.9 0.0 1.2 1 0 0 1 1 1 1 Amidohydrolase family ADH_zinc_N PF00107.26 CBK20611.2 - 3.7e-29 101.3 0.0 6.9e-29 100.5 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 CBK20611.2 - 8.6e-20 72.2 0.0 2.3e-19 70.8 0.0 1.7 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 CBK20611.2 - 9.1e-10 38.4 2.2 4.8e-09 36.1 0.3 2.8 2 2 1 3 3 3 1 Alcohol dehydrogenase GroES-like domain ADH_N_2 PF16884.5 CBK20611.2 - 0.16 11.9 0.0 0.35 10.8 0.0 1.5 1 0 0 1 1 1 0 N-terminal domain of oxidoreductase Proteasome PF00227.26 CBK20612.2 - 8.7e-53 178.6 0.1 1.2e-52 178.1 0.1 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 CBK20612.2 - 1.1e-14 53.8 0.7 1.5e-14 53.4 0.1 1.6 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature CofC PF01983.16 CBK20612.2 - 0.092 11.9 1.5 0.14 11.3 1.5 1.2 1 0 0 1 1 1 0 Guanylyl transferase CofC like Abhydro_lipase PF04083.16 CBK20613.2 - 1.9e-10 40.1 0.0 4.5e-10 39.0 0.0 1.6 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Hydrolase_4 PF12146.8 CBK20613.2 - 2.2e-06 27.1 0.1 0.00056 19.3 0.1 2.5 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 CBK20613.2 - 2.4e-06 28.3 0.0 6e-06 27.0 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 CBK20613.2 - 0.0007 19.3 3.6 0.0042 16.8 1.4 2.5 2 1 0 2 2 2 1 alpha/beta hydrolase fold BAAT_C PF08840.11 CBK20613.2 - 0.0033 17.4 0.0 0.008 16.1 0.0 1.6 1 0 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Peptidase_S9 PF00326.21 CBK20613.2 - 0.021 14.3 0.0 0.053 13.0 0.0 1.6 1 0 0 1 1 1 0 Prolyl oligopeptidase family UDPGP PF01704.18 CBK20614.2 - 2.3e-12 46.3 0.0 3.8e-12 45.6 0.0 1.2 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase Sec1 PF00995.23 CBK20615.2 - 1.1e-14 54.6 0.0 1.1e-14 54.6 0.0 1.0 1 0 0 1 1 1 1 Sec1 family Sec1 PF00995.23 CBK20616.2 - 3.5e-41 142.1 0.3 4.9e-41 141.6 0.3 1.1 1 0 0 1 1 1 1 Sec1 family EF-hand_4 PF12763.7 CBK20618.2 - 2.8e-78 258.6 0.0 1.1e-16 60.6 0.0 5.2 5 0 0 5 5 5 5 Cytoskeletal-regulatory complex EF hand EF-hand_7 PF13499.6 CBK20618.2 - 1.9e-25 89.1 9.0 6.7e-05 23.3 0.1 4.8 4 0 0 4 4 4 4 EF-hand domain pair EF-hand_1 PF00036.32 CBK20618.2 - 1.8e-18 64.6 13.5 0.012 15.1 0.1 7.8 8 0 0 8 8 8 4 EF hand EF-hand_6 PF13405.6 CBK20618.2 - 5.9e-15 53.9 15.0 0.56 10.3 0.1 8.2 8 0 0 8 8 8 4 EF-hand domain EF-hand_8 PF13833.6 CBK20618.2 - 4e-12 45.8 0.8 0.39 10.6 0.0 4.3 4 0 0 4 4 4 4 EF-hand domain pair ArAE_2 PF10334.9 CBK20618.2 - 4.4e-08 33.2 10.3 1.9 8.3 0.0 5.2 4 1 1 5 5 5 4 Aromatic acid exporter family member 2 Na_trans_assoc PF06512.13 CBK20618.2 - 3.5e-07 30.7 10.7 0.69 10.2 0.0 5.2 2 1 0 3 3 3 2 Sodium ion transport-associated EF-hand_5 PF13202.6 CBK20618.2 - 3.8e-07 29.3 24.2 0.51 9.9 0.1 7.3 8 0 0 8 8 8 4 EF hand End3 PF12761.7 CBK20618.2 - 7.4e-05 23.0 20.9 8.7 6.5 0.1 6.5 6 0 0 6 6 6 1 Actin cytoskeleton-regulatory complex protein END3 FAM176 PF14851.6 CBK20618.2 - 0.00035 20.2 20.9 0.85 9.3 0.4 5.5 6 0 0 6 6 5 3 FAM176 family VCBS PF13517.6 CBK20618.2 - 0.0028 18.2 6.7 48 4.7 0.1 4.3 4 0 0 4 4 4 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella Secretin_N PF03958.17 CBK20618.2 - 0.01 16.2 0.6 1.8e+02 2.6 0.0 4.4 4 0 0 4 4 4 0 Bacterial type II/III secretion system short domain DUF5414 PF17435.2 CBK20618.2 - 0.042 13.5 0.0 1.6e+02 1.8 0.0 3.9 4 0 0 4 4 4 0 Family of unknown function (DUF5414) DUF2052 PF09747.9 CBK20618.2 - 0.38 10.8 61.2 0.21 11.7 3.2 6.6 6 0 0 6 6 5 0 Coiled-coil domain containing protein (DUF2052) FG-GAP PF01839.23 CBK20618.2 - 1 9.6 6.0 1.7e+02 2.4 0.1 4.1 4 0 0 4 4 4 0 FG-GAP repeat Spt5_N PF11942.8 CBK20618.2 - 1.5 9.8 44.7 1.4 10.0 1.2 6.1 6 0 0 6 6 5 0 Spt5 transcription elongation factor, acidic N-terminal VSG_B PF13206.6 CBK20618.2 - 2.9 7.0 6.9 8 5.6 6.9 1.7 1 0 0 1 1 1 0 Trypanosomal VSG domain BHD_2 PF10404.9 CBK20618.2 - 6.5 7.8 34.4 17 6.4 1.8 5.7 5 0 0 5 5 5 0 Rad4 beta-hairpin domain 2 Ureide_permease PF07168.11 CBK20619.2 - 4.8e-07 28.9 13.8 0.00025 19.9 9.0 2.3 2 1 0 2 2 2 2 Ureide permease Sugar_transport PF06800.12 CBK20619.2 - 0.00084 18.8 1.6 0.00084 18.8 1.6 2.9 3 0 0 3 3 3 1 Sugar transport protein Totivirus_coat PF05518.11 CBK20619.2 - 3.1 5.7 8.9 4.1 5.3 8.9 1.1 1 0 0 1 1 1 0 Totivirus coat protein CCT PF06203.14 CBK20620.2 - 2.1e-16 59.7 15.8 3.1e-16 59.1 15.8 1.3 1 0 0 1 1 1 1 CCT motif CCT_2 PF09425.10 CBK20620.2 - 0.00086 19.1 2.5 0.0022 17.9 2.5 1.7 1 0 0 1 1 1 1 Divergent CCT motif DUF2169 PF09937.9 CBK20620.2 - 0.038 13.5 0.0 0.058 12.8 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2169) B56 PF01603.20 CBK20621.2 - 7.3e-123 410.6 3.1 3.6e-122 408.3 0.7 2.0 2 0 0 2 2 2 2 Protein phosphatase 2A regulatory B subunit (B56 family) PH PF00169.29 CBK20621.2 - 0.095 13.2 0.1 0.38 11.3 0.0 2.0 2 0 0 2 2 2 0 PH domain NADH_B2 PF14813.6 CBK20622.2 - 3.9e-06 26.6 3.7 5.4e-06 26.1 3.7 1.2 1 0 0 1 1 1 1 NADH dehydrogenase 1 beta subcomplex subunit 2 RRM_2 PF04059.12 CBK20623.2 - 5.4e-25 87.4 0.3 9.4e-25 86.7 0.3 1.4 1 0 0 1 1 1 1 RNA recognition motif 2 ANAPC4_WD40 PF12894.7 CBK20624.2 - 4.7e-06 26.8 0.0 7e-05 23.1 0.0 2.7 2 2 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 CBK20624.2 - 0.00026 21.7 0.1 0.03 15.2 0.0 2.9 3 0 0 3 3 3 1 WD domain, G-beta repeat PQQ PF01011.21 CBK20624.2 - 0.0051 16.7 0.0 0.32 11.0 0.0 2.8 2 0 0 2 2 2 1 PQQ enzyme repeat ELYS-bb PF16687.5 CBK20624.2 - 0.01 14.5 0.0 0.014 14.0 0.0 1.1 1 0 0 1 1 1 0 beta-propeller of ELYS nucleoporin ESCRT-II PF05871.12 CBK20625.2 - 1.5e-31 109.5 0.0 1.9e-31 109.2 0.0 1.1 1 0 0 1 1 1 1 ESCRT-II complex subunit Cytochrom_B_C PF00032.17 CBK20625.2 - 0.02 15.2 0.9 0.049 13.9 0.8 1.7 2 0 0 2 2 2 0 Cytochrome b(C-terminal)/b6/petD Git3 PF11710.8 CBK20625.2 - 0.14 12.0 5.5 0.12 12.1 3.9 1.7 2 0 0 2 2 2 0 G protein-coupled glucose receptor regulating Gpa2 Nucleoporin_C PF03177.14 CBK20625.2 - 0.16 10.7 0.0 0.19 10.4 0.0 1.2 1 0 0 1 1 1 0 Non-repetitive/WGA-negative nucleoporin C-terminal LAT PF15234.6 CBK20626.2 - 0.0024 17.7 0.6 0.0039 17.0 0.6 1.3 1 0 0 1 1 1 1 Linker for activation of T-cells 7TM_GPCR_Srd PF10317.9 CBK20626.2 - 0.0028 16.9 0.9 1.8 7.7 0.2 2.3 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srd Trypan_PARP PF05887.11 CBK20626.2 - 0.01 15.8 0.1 0.01 15.8 0.1 1.9 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) FAM176 PF14851.6 CBK20626.2 - 0.97 9.1 2.2 0.71 9.5 0.3 1.7 2 0 0 2 2 2 0 FAM176 family DUF2187 PF09953.9 CBK20628.2 - 0.00053 19.9 0.6 0.0012 18.8 0.6 1.6 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2187) HAS-barrel PF09378.10 CBK20628.2 - 0.0041 17.2 4.5 0.22 11.7 0.3 3.1 1 1 2 3 3 3 2 HAS barrel domain CAMSAP_CKK PF08683.11 CBK20628.2 - 0.026 14.7 0.0 0.043 13.9 0.0 1.3 1 0 0 1 1 1 0 Microtubule-binding calmodulin-regulated spectrin-associated Sod_Cu PF00080.20 CBK20629.2 - 5.1e-33 114.2 0.6 5.9e-33 114.0 0.6 1.0 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) HSP20 PF00011.21 CBK20630.2 - 2.5e-10 40.4 0.0 2.6e-10 40.3 0.0 1.0 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 CBK20630.2 - 0.016 14.7 0.0 0.02 14.5 0.0 1.4 1 1 0 1 1 1 0 HSP20-like domain found in ArsA UQ_con PF00179.26 CBK20631.2 - 1.2e-43 148.1 0.0 1.8e-43 147.5 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 CBK20631.2 - 0.0089 15.7 0.0 0.013 15.2 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 CBK20631.2 - 0.073 13.4 0.0 0.11 12.8 0.0 1.5 1 0 0 1 1 1 0 RWD domain MeaB PF03308.16 CBK20632.2 - 1.5e-82 276.5 0.0 3.9e-82 275.2 0.0 1.6 1 1 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB cobW PF02492.19 CBK20632.2 - 4e-07 29.8 0.2 1.7e-06 27.8 0.2 1.9 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain ATP_bind_1 PF03029.17 CBK20632.2 - 6.4e-06 26.1 0.0 1.5e-05 24.9 0.0 1.6 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_30 PF13604.6 CBK20632.2 - 0.00068 19.4 0.0 0.0012 18.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain CbiA PF01656.23 CBK20632.2 - 0.0007 19.6 0.0 0.0016 18.5 0.0 1.6 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_18 PF13238.6 CBK20632.2 - 0.0012 19.3 0.1 0.0046 17.5 0.1 2.0 2 0 0 2 2 1 1 AAA domain AAA_29 PF13555.6 CBK20632.2 - 0.0014 18.3 0.0 0.0031 17.2 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.6 CBK20632.2 - 0.0021 18.4 0.1 0.026 14.8 0.0 2.2 2 0 0 2 2 2 1 AAA domain CLP1_P PF16575.5 CBK20632.2 - 0.003 17.4 0.0 0.0089 15.8 0.0 1.8 1 0 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop IstB_IS21 PF01695.17 CBK20632.2 - 0.0031 17.3 0.0 0.0054 16.5 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein SRP54 PF00448.22 CBK20632.2 - 0.0037 16.9 0.1 0.049 13.3 0.1 2.2 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain Thymidylate_kin PF02223.17 CBK20632.2 - 0.0042 16.8 0.0 0.0073 16.0 0.0 1.4 1 0 0 1 1 1 1 Thymidylate kinase AAA_24 PF13479.6 CBK20632.2 - 0.0063 16.3 0.0 0.012 15.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.27 CBK20632.2 - 0.0078 16.7 0.2 0.021 15.4 0.0 1.7 2 0 0 2 2 1 1 ABC transporter NTPase_1 PF03266.15 CBK20632.2 - 0.01 15.7 0.0 0.024 14.5 0.0 1.6 1 0 0 1 1 1 0 NTPase Glyco_trans_4_4 PF13579.6 CBK20632.2 - 0.025 15.0 0.0 0.13 12.7 0.0 2.1 1 1 0 1 1 1 0 Glycosyl transferase 4-like domain GTP_EFTU PF00009.27 CBK20632.2 - 0.027 14.0 0.0 2.8 7.4 0.0 2.3 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 CBK20632.2 - 0.034 14.2 0.0 0.12 12.4 0.0 2.0 1 1 0 1 1 1 0 50S ribosome-binding GTPase FtsK_SpoIIIE PF01580.18 CBK20632.2 - 0.049 13.0 0.0 0.083 12.2 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA PF00004.29 CBK20632.2 - 0.06 13.8 0.1 0.16 12.4 0.0 1.8 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) MobB PF03205.14 CBK20632.2 - 0.061 13.2 0.1 0.2 11.5 0.0 1.9 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B ParA PF10609.9 CBK20632.2 - 0.068 12.6 0.1 0.39 10.1 0.0 1.9 2 0 0 2 2 2 0 NUBPL iron-transfer P-loop NTPase ArsA_ATPase PF02374.15 CBK20632.2 - 0.075 12.2 1.3 0.12 11.5 0.3 1.7 2 0 0 2 2 2 0 Anion-transporting ATPase Mg_chelatase PF01078.21 CBK20632.2 - 0.11 11.8 0.0 0.22 10.9 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_23 PF13476.6 CBK20632.2 - 0.13 12.7 0.0 0.22 12.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 CBK20632.2 - 0.14 12.5 0.1 0.63 10.5 0.0 2.1 2 0 0 2 2 2 0 RNA helicase APS_kinase PF01583.20 CBK20632.2 - 0.15 12.0 0.0 0.26 11.2 0.0 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase Asp-B-Hydro_N PF05279.11 CBK20633.2 - 0.6 10.1 34.5 0.72 9.9 34.5 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region SLC12 PF03522.15 CBK20633.2 - 4.4 6.2 12.7 5.5 5.9 12.7 1.1 1 0 0 1 1 1 0 Solute carrier family 12 RRM_1 PF00076.22 CBK20634.2 - 1.4e-23 82.5 1.5 9e-20 70.3 0.3 3.1 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Suf PF05843.14 CBK20634.2 - 6.7e-05 23.0 18.5 0.00046 20.3 18.5 2.0 1 1 0 1 1 1 1 Suppressor of forked protein (Suf) RRM_7 PF16367.5 CBK20634.2 - 0.00063 19.8 1.1 2.6 8.2 0.1 3.6 3 1 0 3 3 3 2 RNA recognition motif Nup35_RRM_2 PF14605.6 CBK20634.2 - 0.00083 19.3 0.3 0.0028 17.6 0.1 2.0 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif Nup35_RRM PF05172.13 CBK20634.2 - 0.0091 15.9 0.1 0.018 15.0 0.1 1.5 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif CCDC71L PF15374.6 CBK20634.2 - 4.9 6.3 14.1 0.13 11.5 7.7 1.6 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 71L Ribosomal_S28e PF01200.18 CBK20635.2 - 1.1e-30 105.4 1.0 1.2e-30 105.3 1.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S28e DUF3850 PF12961.7 CBK20635.2 - 0.034 14.2 0.0 0.85 9.7 0.0 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF3850) GNT-I PF03071.15 CBK20636.2 - 1.9e-33 115.9 0.0 2.5e-33 115.5 0.0 1.1 1 0 0 1 1 1 1 GNT-I family PTN13_u3 PF16599.5 CBK20636.2 - 0.1 12.6 4.0 0.16 12.0 4.0 1.2 1 0 0 1 1 1 0 Unstructured linker region on PTN13 protein between PDZ LSM PF01423.22 CBK20637.2 - 1e-13 50.8 0.0 1.4e-13 50.3 0.0 1.3 1 0 0 1 1 1 1 LSM domain Mito_carr PF00153.27 CBK20638.2 - 3e-69 229.0 2.4 3e-22 78.3 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein RRM_1 PF00076.22 CBK20639.2 - 3.1e-18 65.3 0.0 4.2e-18 64.9 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 CBK20639.2 - 0.013 15.4 0.0 0.015 15.1 0.0 1.2 1 0 0 1 1 1 0 Occluded RNA-recognition motif Bromodomain PF00439.25 CBK20640.2 - 1.2e-17 63.8 0.2 1.9e-17 63.1 0.2 1.3 1 0 0 1 1 1 1 Bromodomain Nucleolin_bd PF16725.5 CBK20640.2 - 0.17 11.6 0.2 0.32 10.7 0.2 1.4 1 0 0 1 1 1 0 Nucleolin binding domain ABC_tran PF00005.27 CBK20641.2 - 9.5e-34 116.9 0.0 1.6e-15 57.9 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 CBK20641.2 - 1.3e-13 50.9 1.7 0.0011 18.4 0.0 4.1 3 1 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 CBK20641.2 - 2.3e-13 50.6 1.8 0.0041 17.0 0.0 4.2 2 2 1 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system RLI PF04068.15 CBK20641.2 - 1.3e-11 44.1 3.4 1.3e-11 44.1 3.4 1.9 2 0 0 2 2 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI Fer4 PF00037.27 CBK20641.2 - 4e-08 32.7 3.0 4e-08 32.7 3.0 2.2 2 0 0 2 2 1 1 4Fe-4S binding domain AAA_15 PF13175.6 CBK20641.2 - 1.3e-06 28.4 0.0 0.15 11.7 0.0 3.4 3 0 0 3 3 3 2 AAA ATPase domain Fer4_6 PF12837.7 CBK20641.2 - 8.3e-06 25.7 2.0 8.3e-06 25.7 2.0 2.4 2 0 0 2 2 2 1 4Fe-4S binding domain AAA_16 PF13191.6 CBK20641.2 - 1.4e-05 25.5 0.0 0.2 12.0 0.0 2.6 2 1 0 2 2 2 2 AAA ATPase domain AAA PF00004.29 CBK20641.2 - 5.7e-05 23.6 0.0 0.33 11.4 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 CBK20641.2 - 7.1e-05 22.8 0.1 0.028 14.4 0.1 3.2 2 1 1 3 3 3 1 Rad17 P-loop domain RsgA_GTPase PF03193.16 CBK20641.2 - 0.00011 22.2 0.2 0.42 10.5 0.0 2.9 2 0 0 2 2 2 2 RsgA GTPase NACHT PF05729.12 CBK20641.2 - 0.00011 22.2 0.5 0.051 13.5 0.0 2.6 3 0 0 3 3 2 1 NACHT domain AAA_29 PF13555.6 CBK20641.2 - 0.00012 21.8 0.1 0.64 9.8 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain SRP54 PF00448.22 CBK20641.2 - 0.00015 21.5 1.4 0.045 13.4 0.0 2.2 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_22 PF13401.6 CBK20641.2 - 0.00022 21.5 0.0 0.11 12.7 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_23 PF13476.6 CBK20641.2 - 0.0003 21.3 0.1 0.075 13.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain Fer4_7 PF12838.7 CBK20641.2 - 0.00039 21.0 1.3 0.00039 21.0 1.3 2.3 1 1 2 3 3 2 2 4Fe-4S dicluster domain Fer4_2 PF12797.7 CBK20641.2 - 0.00059 19.8 0.7 0.00059 19.8 0.7 2.4 2 0 0 2 2 2 1 4Fe-4S binding domain AAA_24 PF13479.6 CBK20641.2 - 0.0012 18.6 0.7 0.41 10.3 0.0 2.6 2 1 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 CBK20641.2 - 0.0018 18.6 0.0 3.2 8.2 0.0 2.8 2 0 0 2 2 2 1 RNA helicase AAA_30 PF13604.6 CBK20641.2 - 0.002 17.9 0.1 0.38 10.4 0.0 2.6 2 0 0 2 2 2 1 AAA domain Fer4_10 PF13237.6 CBK20641.2 - 0.0027 17.8 1.4 0.0027 17.8 1.4 2.4 1 1 1 2 2 2 2 4Fe-4S dicluster domain AAA_33 PF13671.6 CBK20641.2 - 0.0028 17.8 0.0 1.6 8.9 0.0 2.6 2 0 0 2 2 2 1 AAA domain TsaE PF02367.17 CBK20641.2 - 0.0032 17.5 0.0 0.13 12.3 0.0 2.4 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE SbcCD_C PF13558.6 CBK20641.2 - 0.004 17.4 0.0 0.52 10.6 0.0 2.9 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit Fer4_16 PF13484.6 CBK20641.2 - 0.0049 17.8 0.2 0.0049 17.8 0.2 2.3 2 0 0 2 2 1 1 4Fe-4S double cluster binding domain Fer4_9 PF13187.6 CBK20641.2 - 0.0051 17.0 10.7 0.0094 16.1 10.7 1.5 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_21 PF14697.6 CBK20641.2 - 0.0083 16.2 11.1 0.022 14.9 11.1 1.7 1 1 0 1 1 1 1 4Fe-4S dicluster domain Thymidylate_kin PF02223.17 CBK20641.2 - 0.013 15.2 0.1 2.1 8.0 0.0 2.5 2 0 0 2 2 2 0 Thymidylate kinase AAA_5 PF07728.14 CBK20641.2 - 0.015 15.3 0.6 1.2 9.1 0.0 2.9 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) AAA_28 PF13521.6 CBK20641.2 - 0.021 15.1 1.7 2.4 8.4 0.0 2.8 3 0 0 3 3 2 0 AAA domain AAA_18 PF13238.6 CBK20641.2 - 0.032 14.8 0.0 7.7 7.1 0.0 2.5 2 0 0 2 2 2 0 AAA domain DUF815 PF05673.13 CBK20641.2 - 0.034 13.3 0.2 2.3 7.3 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_7 PF12775.7 CBK20641.2 - 0.042 13.4 0.1 1.2 8.6 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region VirE PF05272.11 CBK20641.2 - 0.055 13.2 0.0 7.3 6.3 0.0 2.3 2 0 0 2 2 2 0 Virulence-associated protein E AAA_13 PF13166.6 CBK20641.2 - 0.11 11.1 0.5 0.22 10.1 0.0 1.7 2 0 0 2 2 1 0 AAA domain AAA_19 PF13245.6 CBK20641.2 - 0.12 12.8 0.2 1.5 9.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.6 CBK20641.2 - 0.12 12.4 0.0 12 5.9 0.0 2.9 3 0 0 3 3 2 0 AAA domain MMR_HSR1 PF01926.23 CBK20641.2 - 0.13 12.3 1.3 14 5.8 0.0 2.9 3 0 0 3 3 2 0 50S ribosome-binding GTPase DUF359 PF04019.12 CBK20641.2 - 0.14 11.8 0.1 0.44 10.2 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF359) Fer4_8 PF13183.6 CBK20641.2 - 0.15 12.6 0.3 0.15 12.6 0.3 2.2 2 0 0 2 2 1 0 4Fe-4S dicluster domain NB-ARC PF00931.22 CBK20641.2 - 0.18 11.0 0.0 12 5.0 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain TrwB_AAD_bind PF10412.9 CBK20641.2 - 0.23 10.3 0.4 8.1 5.2 0.1 2.1 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain NTPase_1 PF03266.15 CBK20641.2 - 1.1 9.1 4.9 8.1 6.3 0.0 3.2 4 0 0 4 4 3 0 NTPase Fer4_4 PF12800.7 CBK20641.2 - 3.8 8.3 15.1 0.14 12.7 3.2 2.5 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_3 PF12798.7 CBK20641.2 - 7.4 7.8 14.2 0.085 13.8 4.2 2.5 2 1 0 2 2 1 0 4Fe-4S binding domain EMG1 PF03587.14 CBK20642.2 - 4.8e-61 205.8 0.0 5.4e-61 205.7 0.0 1.0 1 0 0 1 1 1 1 EMG1/NEP1 methyltransferase ThiF PF00899.21 CBK20643.2 - 1.2e-06 28.1 0.0 1.5e-06 27.7 0.0 1.1 1 0 0 1 1 1 1 ThiF family ThiF PF00899.21 CBK20644.2 - 8.9e-29 100.6 0.0 1.1e-28 100.3 0.0 1.0 1 0 0 1 1 1 1 ThiF family UDPG_MGDP_dh_N PF03721.14 CBK20644.2 - 6e-05 22.7 0.0 7.2e-05 22.4 0.0 1.1 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 2-Hacid_dh_C PF02826.19 CBK20644.2 - 0.00024 20.5 0.0 0.00027 20.4 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain FAD_binding_3 PF01494.19 CBK20644.2 - 0.0054 16.0 0.2 0.0068 15.7 0.2 1.1 1 0 0 1 1 1 1 FAD binding domain Shikimate_DH PF01488.20 CBK20644.2 - 0.016 15.2 0.0 0.02 14.9 0.0 1.2 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Ldh_1_N PF00056.23 CBK20644.2 - 0.018 15.1 0.1 0.028 14.5 0.1 1.3 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain Sacchrp_dh_NADP PF03435.18 CBK20644.2 - 0.026 14.8 0.0 0.03 14.6 0.0 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain PHD_Oberon PF07227.11 CBK20644.2 - 0.031 14.2 0.0 0.045 13.6 0.0 1.2 1 0 0 1 1 1 0 PHD - plant homeodomain finger protein PglD_N PF17836.1 CBK20644.2 - 0.031 14.9 0.0 0.04 14.6 0.0 1.3 1 0 0 1 1 1 0 PglD N-terminal domain ApbA PF02558.16 CBK20644.2 - 0.04 13.6 0.0 0.053 13.2 0.0 1.2 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Pyr_redox_2 PF07992.14 CBK20644.2 - 0.055 12.7 0.0 0.061 12.5 0.0 1.1 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.18 CBK20644.2 - 0.087 13.1 0.0 0.11 12.7 0.0 1.2 1 0 0 1 1 1 0 TrkA-N domain ELFV_dehydrog PF00208.21 CBK20644.2 - 0.11 12.2 0.1 0.13 12.0 0.1 1.1 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase DUF647 PF04884.14 CBK20645.2 - 5.3e-28 98.3 0.9 7.9e-28 97.7 0.9 1.3 1 0 0 1 1 1 1 Vitamin B6 photo-protection and homoeostasis DUF1860 PF08949.10 CBK20646.2 - 0.11 12.2 0.2 0.21 11.3 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1860) MORN PF02493.20 CBK20647.2 - 0.0023 17.7 21.3 0.066 13.1 1.4 7.4 6 0 0 6 6 6 3 MORN repeat MORN PF02493.20 CBK20648.2 - 9.4e-11 41.0 36.1 0.0028 17.4 0.9 7.9 8 0 0 8 8 8 5 MORN repeat DUF902 PF06001.13 CBK20648.2 - 0.13 12.7 2.5 0.4 11.2 0.1 2.8 3 0 0 3 3 3 0 Domain of Unknown Function (DUF902) ABC_tran PF00005.27 CBK20649.2 - 2.1e-31 109.3 0.0 3.9e-31 108.4 0.0 1.5 2 0 0 2 2 2 1 ABC transporter SMC_N PF02463.19 CBK20649.2 - 0.00023 20.7 0.4 0.22 11.0 0.1 2.2 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 CBK20649.2 - 0.0006 19.8 0.0 0.001 19.0 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_29 PF13555.6 CBK20649.2 - 0.00069 19.3 0.1 0.0014 18.3 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_21 PF13304.6 CBK20649.2 - 0.0024 17.7 4.5 0.027 14.3 1.1 2.4 1 1 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 CBK20649.2 - 0.0055 17.1 0.2 0.0087 16.5 0.2 1.4 1 1 0 1 1 1 1 AAA ATPase domain MMR_HSR1 PF01926.23 CBK20649.2 - 0.014 15.5 0.1 0.025 14.7 0.1 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_33 PF13671.6 CBK20649.2 - 0.029 14.5 0.1 0.065 13.4 0.1 1.6 1 1 0 1 1 1 0 AAA domain SbcCD_C PF13558.6 CBK20649.2 - 0.048 13.9 0.4 1.1 9.6 0.4 2.3 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_30 PF13604.6 CBK20649.2 - 0.054 13.2 0.0 0.11 12.2 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_23 PF13476.6 CBK20649.2 - 0.055 14.0 0.3 0.055 14.0 0.3 1.7 2 1 0 2 2 1 0 AAA domain Roc PF08477.13 CBK20649.2 - 0.094 12.9 0.0 0.17 12.1 0.0 1.3 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase AAA_15 PF13175.6 CBK20649.2 - 0.099 12.3 0.0 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain Dynamin_N PF00350.23 CBK20649.2 - 0.1 12.6 0.5 0.23 11.5 0.5 1.5 1 0 0 1 1 1 0 Dynamin family FtsK_SpoIIIE PF01580.18 CBK20649.2 - 0.11 11.8 0.1 0.2 11.0 0.1 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_22 PF13401.6 CBK20649.2 - 0.15 12.3 0.2 0.4 10.9 0.1 1.7 2 0 0 2 2 2 0 AAA domain SRPRB PF09439.10 CBK20649.2 - 0.16 11.4 0.0 0.25 10.7 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Ribosomal_L10 PF00466.20 CBK20650.2 - 3.8e-20 71.9 0.2 9.8e-20 70.6 0.2 1.6 1 0 0 1 1 1 1 Ribosomal protein L10 RL10P_insert PF17777.1 CBK20650.2 - 8.5e-18 64.1 0.1 2.8e-17 62.5 0.1 1.9 2 0 0 2 2 2 1 Insertion domain in 60S ribosomal protein L10P Mito_carr PF00153.27 CBK20650.2 - 5e-17 61.6 0.2 2.1e-09 37.2 0.1 2.5 2 0 0 2 2 2 2 Mitochondrial carrier protein Ribosomal_60s PF00428.19 CBK20650.2 - 2.5e-11 44.0 6.2 5e-11 43.0 6.2 1.5 1 0 0 1 1 1 1 60s Acidic ribosomal protein WD40 PF00400.32 CBK20651.2 - 3.5e-20 72.0 4.3 3.4e-07 30.9 0.1 4.2 4 0 0 4 4 4 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBK20651.2 - 9.3e-08 32.3 0.1 0.00019 21.6 0.0 3.1 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 CBK20651.2 - 1.5e-05 25.0 0.1 0.015 15.2 0.0 2.2 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 CBK20651.2 - 0.0048 16.3 0.0 1.2 8.4 0.0 2.5 3 0 0 3 3 3 2 WD40-like domain Nup160 PF11715.8 CBK20651.2 - 0.017 13.8 0.0 0.03 13.0 0.0 1.3 1 0 0 1 1 1 0 Nucleoporin Nup120/160 Med17 PF10156.9 CBK20651.2 - 0.048 12.4 5.1 0.063 12.0 5.1 1.2 1 0 0 1 1 1 0 Subunit 17 of Mediator complex ELM2 PF01448.24 CBK20651.2 - 0.053 14.3 0.1 6.5 7.6 0.0 2.5 2 1 0 2 2 2 0 ELM2 domain FAM176 PF14851.6 CBK20651.2 - 0.066 12.9 5.8 0.1 12.2 5.8 1.3 1 0 0 1 1 1 0 FAM176 family SDA1 PF05285.12 CBK20651.2 - 0.39 10.1 11.7 0.46 9.9 11.7 1.1 1 0 0 1 1 1 0 SDA1 Tma16 PF11176.8 CBK20651.2 - 0.44 10.4 7.1 0.7 9.8 7.1 1.2 1 0 0 1 1 1 0 Translation machinery-associated protein 16 TRAP_alpha PF03896.16 CBK20651.2 - 1.2 8.3 5.3 1.4 8.0 5.3 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Nop14 PF04147.12 CBK20651.2 - 1.7 6.8 13.6 1.9 6.6 13.6 1.0 1 0 0 1 1 1 0 Nop14-like family UL11 PF11094.8 CBK20651.2 - 2.9 7.8 5.6 7.9 6.5 5.6 1.7 1 0 0 1 1 1 0 Membrane-associated tegument protein Ribosomal_60s PF00428.19 CBK20651.2 - 4.8 7.8 15.4 10 6.8 15.4 1.5 1 0 0 1 1 1 0 60s Acidic ribosomal protein PI3K_1B_p101 PF10486.9 CBK20651.2 - 5.4 4.7 6.8 6.9 4.3 6.8 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit RRN3 PF05327.11 CBK20651.2 - 8.4 4.8 8.0 9.9 4.6 8.0 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 SIR2 PF02146.17 CBK20652.2 - 9.1e-54 182.0 0.0 1.1e-53 181.7 0.0 1.1 1 0 0 1 1 1 1 Sir2 family MORN PF02493.20 CBK20654.2 - 5.8e-10 38.5 10.5 0.0002 21.1 0.1 3.7 3 0 0 3 3 3 3 MORN repeat MORN_2 PF07661.13 CBK20654.2 - 0.016 15.3 4.6 0.57 10.6 0.2 3.1 3 0 0 3 3 3 0 MORN repeat variant OCRE PF17780.1 CBK20654.2 - 0.38 10.8 4.7 4.6 7.3 0.0 3.1 3 0 0 3 3 3 0 OCRE domain Guanylate_cyc_2 PF09778.9 CBK20655.2 - 3.2e-22 78.9 0.3 4.7e-22 78.4 0.3 1.2 1 0 0 1 1 1 1 Guanylylate cyclase Peptidase_C39_2 PF13529.6 CBK20655.2 - 0.012 16.2 0.1 0.042 14.4 0.1 2.0 1 1 0 2 2 2 0 Peptidase_C39 like family Peptidase_C70 PF12385.8 CBK20655.2 - 0.15 12.0 0.0 0.22 11.5 0.0 1.4 1 0 0 1 1 1 0 Papain-like cysteine protease AvrRpt2 RRM_1 PF00076.22 CBK20656.2 - 5.8e-11 42.1 0.0 8.7e-11 41.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 CBK20656.2 - 0.085 12.5 0.0 0.09 12.4 0.0 1.1 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CHORD PF04968.12 CBK20657.2 - 1.6e-48 163.2 32.5 1.1e-24 86.9 9.6 2.8 2 1 1 3 3 3 2 CHORD DEC-1_N PF04625.13 CBK20657.2 - 0.0088 15.1 8.1 0.011 14.8 8.1 1.1 1 0 0 1 1 1 1 DEC-1 protein, N-terminal region DUF4813 PF16072.5 CBK20657.2 - 0.067 12.8 20.1 0.12 12.0 20.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4813) BTK PF00779.19 CBK20657.2 - 0.65 9.9 23.6 0.91 9.4 0.2 5.6 6 1 0 6 6 6 0 BTK motif PRCC PF10253.9 CBK20657.2 - 0.69 10.7 4.6 0.91 10.3 4.6 1.2 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting SAP130_C PF16014.5 CBK20657.2 - 8.7 5.3 12.7 11 4.9 12.7 1.1 1 0 0 1 1 1 0 Histone deacetylase complex subunit SAP130 C-terminus Ank_4 PF13637.6 CBK20658.2 - 4.6e-11 43.0 0.3 1.6e-07 31.8 0.0 2.3 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 CBK20658.2 - 6e-11 42.4 0.0 1.6e-10 41.0 0.0 1.8 1 1 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 CBK20658.2 - 6.6e-09 36.2 0.1 7.5e-08 32.9 0.0 2.0 1 1 0 2 2 2 1 Ankyrin repeats (3 copies) Ank PF00023.30 CBK20658.2 - 5.9e-08 32.8 0.0 4.4e-07 30.0 0.1 2.3 3 0 0 3 3 3 1 Ankyrin repeat Ank_3 PF13606.6 CBK20658.2 - 1.6e-05 24.9 0.0 0.0017 18.7 0.0 2.8 2 0 0 2 2 2 1 Ankyrin repeat TPR_1 PF00515.28 CBK20658.2 - 0.00032 20.4 0.3 0.0038 17.0 0.2 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.6 CBK20658.2 - 0.00084 19.2 0.1 0.011 15.7 0.0 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.17 CBK20658.2 - 0.003 17.6 1.8 0.02 15.0 0.1 2.7 3 0 0 3 3 2 1 Tetratricopeptide repeat Cytochrom_B562 PF07361.11 CBK20658.2 - 0.0072 17.0 0.1 0.065 13.9 0.0 2.2 2 0 0 2 2 2 1 Cytochrome b562 TPR_12 PF13424.6 CBK20658.2 - 0.0075 16.5 0.0 0.065 13.5 0.0 2.4 3 0 0 3 3 3 1 Tetratricopeptide repeat DUF2385 PF09539.10 CBK20658.2 - 0.04 14.4 0.4 0.1 13.2 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2385) TPR_8 PF13181.6 CBK20658.2 - 0.063 13.5 0.2 1.6 9.1 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_11 PF13414.6 CBK20658.2 - 0.079 12.7 0.0 0.65 9.7 0.0 2.3 2 0 0 2 2 2 0 TPR repeat DUF1657 PF07870.11 CBK20658.2 - 0.096 12.6 1.7 3.3 7.7 0.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1657) DUF4810 PF16068.5 CBK20658.2 - 0.11 13.0 0.2 0.51 10.9 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4810) PPR PF01535.20 CBK20658.2 - 0.29 11.5 2.6 3.4 8.1 0.1 3.6 4 0 0 4 4 4 0 PPR repeat UBD PF16455.5 CBK20659.2 - 7.7e-08 32.5 0.0 1.1e-07 32.0 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-binding domain PurS PF02700.14 CBK20659.2 - 0.047 13.9 0.1 0.12 12.6 0.1 1.6 1 0 0 1 1 1 0 Phosphoribosylformylglycinamidine (FGAM) synthase Swi3 PF07962.12 CBK20660.2 - 0.12 12.4 0.0 0.13 12.3 0.0 1.0 1 0 0 1 1 1 0 Replication Fork Protection Component Swi3 MMS1_N PF10433.9 CBK20661.2 - 1.2e-15 57.1 0.0 1.6e-15 56.8 0.0 1.1 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.15 CBK20662.2 - 4.6e-12 45.9 0.0 5.1e-12 45.7 0.0 1.0 1 0 0 1 1 1 1 CPSF A subunit region Sigma70_r4 PF04545.16 CBK20662.2 - 0.038 13.5 0.0 0.069 12.7 0.0 1.4 1 0 0 1 1 1 0 Sigma-70, region 4 DUF2281 PF10047.9 CBK20663.2 - 0.09 13.5 1.1 0.09 13.5 1.1 2.4 3 1 0 3 3 3 0 Protein of unknown function (DUF2281) PIN_6 PF17146.4 CBK20664.2 - 2.2e-05 24.8 0.0 2.5e-05 24.7 0.0 1.1 1 0 0 1 1 1 1 PIN domain of ribonuclease HSP70 PF00012.20 CBK20665.2 - 5.6e-237 787.7 20.3 1.2e-190 634.7 3.3 2.0 1 1 1 2 2 2 2 Hsp70 protein MreB_Mbl PF06723.13 CBK20665.2 - 1.5e-19 70.0 1.7 1.1e-17 63.9 0.6 2.2 2 0 0 2 2 2 2 MreB/Mbl protein Hydantoinase_A PF01968.18 CBK20665.2 - 0.0013 18.0 4.0 0.038 13.2 0.2 2.8 3 0 0 3 3 3 2 Hydantoinase/oxoprolinase FtsA PF14450.6 CBK20665.2 - 0.011 16.2 5.6 0.38 11.2 0.1 3.7 3 2 0 3 3 3 0 Cell division protein FtsA DUF1464 PF07318.12 CBK20665.2 - 0.012 14.8 0.3 0.33 10.1 0.0 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF1464) LRR_8 PF13855.6 CBK20666.2 - 2.7e-06 27.1 0.5 0.0042 16.8 0.0 3.5 3 1 0 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 CBK20666.2 - 0.0096 16.3 4.0 7 7.2 0.6 4.4 1 1 3 4 4 4 2 Leucine Rich repeats (2 copies) MA3 PF02847.17 CBK20667.2 - 2.7e-14 53.1 0.7 7.5e-14 51.7 0.7 1.8 1 0 0 1 1 1 1 MA3 domain MIF4G PF02854.19 CBK20667.2 - 1.5e-12 47.6 2.4 1.5e-12 47.6 2.4 1.7 2 0 0 2 2 2 1 MIF4G domain YCII PF03795.14 CBK20668.2 - 1.1e-08 35.4 0.0 1.4e-08 35.0 0.0 1.1 1 0 0 1 1 1 1 YCII-related domain Tom7 PF08038.12 CBK20669.2 - 5.2e-10 38.8 0.5 5.5e-10 38.7 0.5 1.1 1 0 0 1 1 1 1 TOM7 family Ribosomal_L25p PF01386.19 CBK20669.2 - 0.089 13.3 0.0 0.089 13.3 0.0 1.0 1 0 0 1 1 1 0 Ribosomal L25p family Spc7 PF08317.11 CBK20670.2 - 0.0029 16.6 19.9 0.0031 16.4 19.9 1.0 1 0 0 1 1 1 1 Spc7 kinetochore protein GOLGA2L5 PF15070.6 CBK20670.2 - 0.0055 15.4 18.7 0.0061 15.3 18.7 1.0 1 0 0 1 1 1 1 Putative golgin subfamily A member 2-like protein 5 DUF3584 PF12128.8 CBK20670.2 - 0.01 13.4 15.3 0.012 13.2 15.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Hemerythrin PF01814.23 CBK20670.2 - 0.013 16.1 2.9 0.019 15.6 2.9 1.3 1 0 0 1 1 1 0 Hemerythrin HHE cation binding domain EMP24_GP25L PF01105.24 CBK20670.2 - 0.025 14.5 7.7 0.025 14.5 7.7 2.0 1 1 1 2 2 2 0 emp24/gp25L/p24 family/GOLD TolA_bind_tri PF16331.5 CBK20670.2 - 0.029 14.4 12.1 0.029 14.4 12.1 2.2 1 1 1 2 2 2 0 TolA binding protein trimerisation Pex19 PF04614.12 CBK20670.2 - 0.037 13.8 11.9 0.046 13.5 11.9 1.1 1 0 0 1 1 1 0 Pex19 protein family KASH_CCD PF14662.6 CBK20670.2 - 0.041 13.7 21.2 0.049 13.5 21.2 1.1 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH TMPIT PF07851.13 CBK20670.2 - 0.061 12.6 13.8 0.071 12.4 13.8 1.1 1 0 0 1 1 1 0 TMPIT-like protein TINF2_N PF14973.6 CBK20670.2 - 0.072 13.4 9.7 0.091 13.1 8.6 1.6 1 1 1 2 2 2 0 TERF1-interacting nuclear factor 2 N-terminus DUF812 PF05667.11 CBK20670.2 - 0.15 10.9 16.6 0.19 10.6 16.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) DUF4795 PF16043.5 CBK20670.2 - 0.16 11.6 16.9 0.22 11.1 15.3 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4795) YscO PF07321.12 CBK20670.2 - 0.19 11.7 25.1 0.18 11.8 24.0 1.4 1 1 0 1 1 1 0 Type III secretion protein YscO HAUS-augmin3 PF14932.6 CBK20670.2 - 0.2 11.2 18.2 0.24 11.0 18.2 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 LemA PF04011.12 CBK20670.2 - 0.24 11.3 8.7 0.34 10.8 8.7 1.2 1 0 0 1 1 1 0 LemA family DUF2203 PF09969.9 CBK20670.2 - 0.31 11.8 10.1 0.61 10.8 10.0 1.6 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) RRN3 PF05327.11 CBK20670.2 - 0.31 9.5 12.0 0.34 9.4 12.0 1.0 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 FUSC PF04632.12 CBK20670.2 - 0.33 9.4 3.0 0.38 9.3 3.0 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family Abi_C PF14355.6 CBK20670.2 - 0.34 11.0 1.3 5.9 7.1 0.1 2.2 1 1 0 2 2 2 0 Abortive infection C-terminus Z1 PF10593.9 CBK20670.2 - 0.36 10.3 6.5 0.4 10.1 6.5 1.1 1 0 0 1 1 1 0 Z1 domain DUF3450 PF11932.8 CBK20670.2 - 0.36 10.1 17.3 0.43 9.8 17.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) ATP11 PF06644.11 CBK20670.2 - 0.4 10.4 8.6 0.44 10.3 8.6 1.1 1 0 0 1 1 1 0 ATP11 protein MMR1 PF08505.10 CBK20670.2 - 0.74 10.1 12.3 0.79 10.0 12.3 1.1 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein Mod_r PF07200.13 CBK20670.2 - 0.74 9.9 21.2 0.95 9.6 21.2 1.1 1 0 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein RasGAP_C PF03836.15 CBK20670.2 - 0.76 9.9 12.6 2.1 8.5 12.5 1.6 1 1 0 1 1 1 0 RasGAP C-terminus BID PF06393.11 CBK20670.2 - 0.8 9.2 9.4 1.2 8.6 9.4 1.2 1 0 0 1 1 1 0 BH3 interacting domain (BID) CorA PF01544.18 CBK20670.2 - 0.83 8.9 8.8 0.26 10.6 0.7 2.0 1 1 1 2 2 2 0 CorA-like Mg2+ transporter protein TssO PF17561.2 CBK20670.2 - 0.85 9.7 9.6 1 9.5 7.8 1.8 1 1 1 2 2 2 0 Type VI secretion system, TssO Rootletin PF15035.6 CBK20670.2 - 0.94 9.5 23.1 0.21 11.6 13.6 2.2 1 1 1 2 2 2 0 Ciliary rootlet component, centrosome cohesion Nup88 PF10168.9 CBK20670.2 - 0.95 7.2 17.8 1.1 7.0 17.8 1.1 1 0 0 1 1 1 0 Nuclear pore component Laminin_II PF06009.12 CBK20670.2 - 0.95 9.5 10.8 1.3 9.0 10.8 1.3 1 0 0 1 1 1 0 Laminin Domain II HemX PF04375.14 CBK20670.2 - 1 8.6 13.6 1.2 8.4 13.6 1.1 1 0 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase Atg14 PF10186.9 CBK20670.2 - 1 8.4 15.6 1.2 8.1 15.6 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF4208 PF13907.6 CBK20670.2 - 1.1 9.8 9.3 1.1 9.7 5.8 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4208) Golgin_A5 PF09787.9 CBK20670.2 - 1.2 8.6 22.6 1.4 8.3 22.6 1.1 1 0 0 1 1 1 0 Golgin subfamily A member 5 FapA PF03961.13 CBK20670.2 - 1.2 7.7 15.2 1.3 7.6 15.2 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A Seryl_tRNA_N PF02403.22 CBK20670.2 - 1.2 9.4 15.9 1.8 8.8 15.9 1.4 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain PMC2NT PF08066.12 CBK20670.2 - 1.3 9.8 7.2 2.7 8.8 7.2 1.6 1 1 0 1 1 1 0 PMC2NT (NUC016) domain Tho2 PF11262.8 CBK20670.2 - 1.4 8.0 13.0 1.7 7.7 13.0 1.1 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 YabA PF06156.13 CBK20670.2 - 1.7 9.3 20.6 4.5 8.0 20.6 1.9 1 1 0 1 1 1 0 Initiation control protein YabA CENP-Q PF13094.6 CBK20670.2 - 1.7 8.8 24.1 2.9 8.1 24.1 1.4 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit OmpH PF03938.14 CBK20670.2 - 1.9 8.8 19.6 2.9 8.2 19.6 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Rgp1 PF08737.10 CBK20670.2 - 2 7.5 9.9 2.3 7.3 9.9 1.0 1 0 0 1 1 1 0 Rgp1 Exonuc_VII_L PF02601.15 CBK20670.2 - 2 7.9 10.9 2.2 7.8 10.9 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit L31 PF09784.9 CBK20670.2 - 2.2 8.8 6.8 1.3 9.5 0.4 2.1 1 1 1 2 2 2 0 Mitochondrial ribosomal protein L31 DUF1664 PF07889.12 CBK20670.2 - 2.3 8.3 12.1 2.6 8.1 8.4 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) ParB PF08775.10 CBK20670.2 - 2.6 8.5 11.0 1.1 9.8 3.7 2.0 1 1 1 2 2 2 0 ParB family APG6_N PF17675.1 CBK20670.2 - 3 8.4 29.4 9.1 6.8 29.4 1.7 1 1 0 1 1 1 0 Apg6 coiled-coil region Bud13 PF09736.9 CBK20670.2 - 3.1 8.2 11.7 3.8 7.9 11.7 1.1 1 0 0 1 1 1 0 Pre-mRNA-splicing factor of RES complex Nop53 PF07767.11 CBK20670.2 - 3.2 7.1 19.1 3.5 6.9 19.1 1.1 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) DUF802 PF05650.11 CBK20670.2 - 3.3 8.2 5.5 3.2 8.3 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF802) SPX PF03105.19 CBK20670.2 - 3.5 7.5 13.0 4.5 7.1 13.0 1.2 1 0 0 1 1 1 0 SPX domain TMEM215 PF15746.5 CBK20670.2 - 3.9 6.9 5.2 4.1 6.8 5.2 1.1 1 0 0 1 1 1 0 TMEM215 family Ax_dynein_light PF10211.9 CBK20670.2 - 4.2 7.3 24.0 6.3 6.7 20.6 2.0 1 1 1 2 2 2 0 Axonemal dynein light chain eIF-4B PF06273.11 CBK20670.2 - 4.3 6.3 13.7 4.5 6.2 13.7 1.1 1 0 0 1 1 1 0 Plant specific eukaryotic initiation factor 4B LPP PF04728.13 CBK20670.2 - 4.7 7.7 9.9 0.33 11.4 3.4 2.1 2 1 0 2 2 2 0 Lipoprotein leucine-zipper V_ATPase_I PF01496.19 CBK20670.2 - 4.7 5.0 12.3 5.1 4.9 12.3 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Fmp27_WPPW PF10359.9 CBK20670.2 - 5.2 5.8 14.2 6.2 5.6 14.2 1.0 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain DUF4407 PF14362.6 CBK20670.2 - 5.2 6.3 10.3 6.7 6.0 10.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) TEX13 PF15186.6 CBK20670.2 - 6.6 6.4 16.9 3.2 7.4 9.9 2.0 1 1 1 2 2 2 0 Testis-expressed sequence 13 protein family DUF1366 PF07104.11 CBK20670.2 - 9.3 6.0 11.8 1.3 8.8 5.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1366) PPDK_N PF01326.19 CBK20671.2 - 3.3e-75 253.4 0.0 3.8e-75 253.2 0.0 1.0 1 0 0 1 1 1 1 Pyruvate phosphate dikinase, PEP/pyruvate binding domain PEP-utilizers PF00391.23 CBK20672.2 - 2.2e-21 75.4 0.1 4.2e-21 74.5 0.1 1.5 1 0 0 1 1 1 1 PEP-utilising enzyme, mobile domain DUF563 PF04577.14 CBK20673.2 - 1.1e-14 55.1 0.0 2.2e-14 54.1 0.0 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF563) UBA_4 PF14555.6 CBK20674.2 - 3.7e-15 55.4 0.2 7.3e-15 54.5 0.2 1.5 1 0 0 1 1 1 1 UBA-like domain Rhodanese PF00581.20 CBK20675.2 - 1.4e-08 35.2 0.1 2.7e-08 34.3 0.1 1.5 1 1 0 1 1 1 1 Rhodanese-like domain HA2 PF04408.23 CBK20676.2 - 1.5e-16 60.6 0.0 1.5e-16 60.6 0.0 3.5 4 1 0 4 4 4 1 Helicase associated domain (HA2) Helicase_C PF00271.31 CBK20676.2 - 5e-11 42.9 0.4 6.9e-10 39.3 0.0 2.7 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DEAD PF00270.29 CBK20676.2 - 9.8e-08 32.0 0.4 2.4e-07 30.7 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.6 CBK20676.2 - 0.0001 22.6 0.0 0.00032 21.0 0.0 1.8 1 0 0 1 1 1 1 AAA domain OB_NTP_bind PF07717.16 CBK20676.2 - 0.00046 20.5 0.0 0.0012 19.1 0.0 1.8 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold AAA_19 PF13245.6 CBK20676.2 - 0.0062 16.9 0.0 0.015 15.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 CBK20676.2 - 0.01 14.9 0.0 0.02 14.0 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein ATPase PF06745.13 CBK20676.2 - 0.021 14.2 0.0 0.021 14.2 0.0 2.1 2 0 0 2 2 2 0 KaiC PhoH PF02562.16 CBK20676.2 - 0.11 12.0 0.0 0.22 10.9 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein DUF913 PF06025.12 CBK20676.2 - 0.37 9.7 12.6 0.16 10.9 0.2 2.8 3 0 0 3 3 3 0 Domain of Unknown Function (DUF913) Galactosyl_T PF01762.21 CBK20677.2 - 6.4e-35 120.7 0.0 8.8e-35 120.3 0.0 1.2 1 0 0 1 1 1 1 Galactosyltransferase DAGK_cat PF00781.24 CBK20678.2 - 7e-21 74.1 0.0 1.1e-20 73.5 0.0 1.3 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain DUF4379 PF14311.6 CBK20679.2 - 1.4e-59 198.2 44.0 4e-20 71.9 5.1 5.9 6 0 0 6 6 6 5 Probable Zinc-ribbon domain DnaJ PF00226.31 CBK20679.2 - 0.035 14.2 0.1 13 6.0 0.0 3.1 3 0 0 3 3 3 0 DnaJ domain DUF3797 PF12677.7 CBK20679.2 - 0.13 12.1 1.6 1 9.3 0.0 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF3797) HMG_box PF00505.19 CBK20680.2 - 0.019 15.3 0.1 0.029 14.8 0.1 1.4 1 1 0 1 1 1 0 HMG (high mobility group) box CdiI_3 PF18616.1 CBK20680.2 - 0.036 13.9 0.0 0.049 13.5 0.0 1.3 1 1 0 1 1 1 0 CDI immunity proteins HMG_box PF00505.19 CBK20681.2 - 4e-13 49.6 2.7 4.7e-13 49.4 2.7 1.1 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 CBK20681.2 - 2.2e-09 37.8 4.7 2.5e-09 37.6 4.7 1.1 1 0 0 1 1 1 1 HMG-box domain HMG_box_5 PF14887.6 CBK20681.2 - 0.068 13.1 2.4 0.09 12.8 2.4 1.3 1 1 0 1 1 1 0 HMG (high mobility group) box 5 DUF2740 PF10872.8 CBK20681.2 - 0.072 13.0 0.1 0.1 12.5 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2740) dCMP_cyt_deam_1 PF00383.23 CBK20683.2 - 4.6e-09 36.1 0.2 6.5e-09 35.6 0.2 1.3 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 CBK20683.2 - 5.5e-07 29.4 0.1 1.2e-06 28.3 0.1 1.6 1 1 0 1 1 1 1 MafB19-like deaminase Ribosomal_L13e PF01294.18 CBK20685.2 - 7.8e-36 123.6 0.1 2.3e-35 122.1 0.1 1.7 1 1 0 1 1 1 1 Ribosomal protein L13e AAA PF00004.29 CBK20686.2 - 1.9e-42 144.8 0.0 3.5e-42 144.0 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CBK20686.2 - 1.1e-10 41.2 0.5 2.1e-10 40.2 0.5 1.5 1 0 0 1 1 1 1 AAA+ lid domain Prot_ATP_ID_OB PF16450.5 CBK20686.2 - 5.2e-07 29.5 0.8 5.2e-07 29.5 0.8 1.7 2 0 0 2 2 1 1 Proteasomal ATPase OB C-terminal domain AAA_2 PF07724.14 CBK20686.2 - 4.6e-06 26.9 0.3 2.3e-05 24.6 0.0 2.2 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 CBK20686.2 - 5.3e-06 26.5 1.1 0.00025 21.0 0.1 3.5 3 1 0 3 3 3 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 CBK20686.2 - 5.6e-06 26.7 0.5 0.0094 16.2 0.1 2.4 1 1 1 2 2 2 2 AAA domain DUF815 PF05673.13 CBK20686.2 - 0.0001 21.5 0.0 0.00027 20.2 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF815) NB-ARC PF00931.22 CBK20686.2 - 0.00028 20.1 0.0 0.38 9.9 0.0 2.5 2 0 0 2 2 2 2 NB-ARC domain AAA_16 PF13191.6 CBK20686.2 - 0.00032 21.1 0.1 0.0067 16.8 0.1 2.2 1 1 1 2 2 2 1 AAA ATPase domain RNA_helicase PF00910.22 CBK20686.2 - 0.0018 18.6 0.0 0.0058 17.0 0.0 1.9 1 0 0 1 1 1 1 RNA helicase ATPase PF06745.13 CBK20686.2 - 0.0024 17.3 0.3 0.32 10.3 0.1 2.5 1 1 0 2 2 2 1 KaiC RuvB_N PF05496.12 CBK20686.2 - 0.0026 17.5 0.0 0.0066 16.2 0.0 1.7 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 CBK20686.2 - 0.0037 17.8 0.4 0.027 15.0 0.0 2.5 2 1 0 2 2 2 1 AAA domain AAA_33 PF13671.6 CBK20686.2 - 0.0058 16.8 0.1 0.087 13.0 0.0 2.3 2 0 0 2 2 2 1 AAA domain TIP49 PF06068.13 CBK20686.2 - 0.014 14.6 0.0 0.03 13.5 0.0 1.6 1 0 0 1 1 1 0 TIP49 P-loop domain TsaE PF02367.17 CBK20686.2 - 0.021 14.8 0.0 0.038 14.0 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE IstB_IS21 PF01695.17 CBK20686.2 - 0.023 14.4 0.0 0.044 13.5 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_24 PF13479.6 CBK20686.2 - 0.024 14.3 0.3 0.083 12.6 0.3 2.0 1 1 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 CBK20686.2 - 0.038 13.7 0.2 0.14 11.8 0.0 1.9 2 1 0 2 2 2 0 Sigma-54 interaction domain NACHT PF05729.12 CBK20686.2 - 0.041 13.8 0.3 0.17 11.8 0.1 2.1 2 0 0 2 2 2 0 NACHT domain AAA_25 PF13481.6 CBK20686.2 - 0.054 13.1 1.1 0.93 9.0 0.2 2.5 1 1 1 2 2 2 0 AAA domain PhoH PF02562.16 CBK20686.2 - 0.062 12.7 0.1 0.34 10.4 0.1 2.1 2 0 0 2 2 2 0 PhoH-like protein AAA_3 PF07726.11 CBK20686.2 - 0.068 13.0 0.0 0.18 11.7 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.21 CBK20686.2 - 0.077 12.4 0.0 0.15 11.4 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Zeta_toxin PF06414.12 CBK20686.2 - 0.085 12.1 0.1 0.21 10.8 0.1 1.6 1 0 0 1 1 1 0 Zeta toxin AAA_7 PF12775.7 CBK20686.2 - 0.11 12.0 0.2 0.29 10.6 0.0 1.7 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_28 PF13521.6 CBK20686.2 - 0.15 12.3 0.0 0.36 11.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain DUF1129 PF06570.11 CBK20687.2 - 0.0029 17.1 0.1 0.0037 16.8 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1129) DUF3611 PF12263.8 CBK20687.2 - 0.021 14.7 0.3 0.027 14.4 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3611) CKS PF01111.19 CBK20688.2 - 6.4e-35 119.2 0.4 8.5e-35 118.8 0.4 1.2 1 0 0 1 1 1 1 Cyclin-dependent kinase regulatory subunit DENN PF02141.21 CBK20689.2 - 0.11 12.5 1.6 0.23 11.4 0.8 1.9 2 0 0 2 2 2 0 DENN (AEX-3) domain ArfGap PF01412.18 CBK20691.2 - 1.1e-24 86.7 0.3 2.2e-24 85.8 0.3 1.5 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf DTHCT PF08070.11 CBK20691.2 - 0.023 15.4 15.1 0.023 15.4 15.1 5.7 1 1 4 5 5 5 0 DTHCT (NUC029) region IRF-2BP1_2 PF11261.8 CBK20691.2 - 0.052 13.1 0.5 0.1 12.2 0.5 1.4 1 0 0 1 1 1 0 Interferon regulatory factor 2-binding protein zinc finger WD40 PF00400.32 CBK20692.2 - 5.1e-07 30.3 2.4 0.34 11.9 0.1 3.3 3 0 0 3 3 3 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBK20692.2 - 1.8e-05 24.9 0.1 0.0046 17.2 0.0 2.3 1 1 2 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain Coatomer_WDAD PF04053.14 CBK20692.2 - 0.015 14.4 0.1 0.021 13.9 0.1 1.2 1 0 0 1 1 1 0 Coatomer WD associated region Kri1_C PF12936.7 CBK20694.2 - 2.5e-29 101.3 1.0 2.5e-29 101.3 1.0 2.6 1 1 2 3 3 3 1 KRI1-like family C-terminal RRN3 PF05327.11 CBK20694.2 - 0.15 10.5 13.4 0.14 10.7 13.4 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 PDCD2_C PF04194.13 CBK20694.2 - 3 7.9 14.5 4 7.5 14.0 1.6 1 1 0 1 1 1 0 Programmed cell death protein 2, C-terminal putative domain AAA_11 PF13086.6 CBK20694.2 - 7 6.3 13.8 0.52 10.1 4.5 2.0 2 0 0 2 2 2 0 AAA domain DUF913 PF06025.12 CBK20694.2 - 8.2 5.3 7.2 12 4.7 7.2 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) DUF5385 PF17359.2 CBK20695.2 - 0.02 14.5 0.7 0.02 14.5 0.7 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5385) HD_assoc PF13286.6 CBK20695.2 - 0.033 14.7 1.4 0.038 14.5 0.2 1.7 2 0 0 2 2 2 0 Phosphohydrolase-associated domain HSP90 PF00183.18 CBK20696.2 - 5.7e-197 655.7 58.4 5.7e-197 655.7 58.4 2.4 1 1 1 2 2 2 1 Hsp90 protein HATPase_c PF02518.26 CBK20696.2 - 5.7e-11 42.9 0.2 1.2e-10 41.8 0.2 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 CBK20696.2 - 4.6e-08 33.0 0.1 4.6e-08 33.0 0.1 2.8 3 0 0 3 3 3 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase UvrD_C PF13361.6 CBK20697.2 - 0.00012 21.6 4.2 0.00022 20.7 0.7 2.6 2 1 1 3 3 3 1 UvrD-like helicase C-terminal domain CortBP2 PF09727.9 CBK20697.2 - 0.25 11.3 1.8 0.86 9.5 0.1 2.1 2 0 0 2 2 2 0 Cortactin-binding protein-2 HisK_N PF09385.10 CBK20697.2 - 0.25 11.3 2.8 2.5 8.1 0.0 2.5 2 0 0 2 2 2 0 Histidine kinase N terminal DUF1160 PF06648.11 CBK20697.2 - 0.68 9.9 3.5 1.2 9.2 0.5 2.6 3 1 0 3 3 3 0 Protein of unknown function (DUF1160) PDDEXK_1 PF12705.7 CBK20698.2 - 2e-15 57.4 0.4 1.9e-14 54.2 0.4 1.9 1 1 0 1 1 1 1 PD-(D/E)XK nuclease superfamily Cas_Cas4 PF01930.17 CBK20698.2 - 0.059 13.5 0.1 0.1 12.7 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function DUF83 TOPRIM_C PF16898.5 CBK20698.2 - 0.099 12.9 0.0 0.24 11.7 0.0 1.8 1 0 0 1 1 1 0 C-terminal associated domain of TOPRIM HSP90 PF00183.18 CBK20700.2 - 6.6e-219 728.1 28.3 8.6e-219 727.7 28.3 1.1 1 0 0 1 1 1 1 Hsp90 protein HATPase_c PF02518.26 CBK20700.2 - 2.1e-15 57.2 0.1 3.9e-15 56.3 0.1 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 CBK20700.2 - 1.1e-10 41.5 0.1 2.7e-10 40.2 0.1 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF4746 PF15928.5 CBK20700.2 - 0.0018 17.8 10.6 0.0018 17.8 10.6 2.7 3 1 0 3 3 3 1 Domain of unknown function (DUF4746) Sulfatase_C PF14707.6 CBK20700.2 - 0.049 14.4 0.1 0.2 12.4 0.1 2.1 1 0 0 1 1 1 0 C-terminal region of aryl-sulfatase DUF913 PF06025.12 CBK20700.2 - 3.1 6.7 6.1 10 5.0 6.1 1.8 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) KH_8 PF17903.1 CBK20701.2 - 3.4e-32 110.4 0.1 8.1e-32 109.2 0.1 1.7 1 0 0 1 1 1 1 Krr1 KH1 domain ABC_membrane PF00664.23 CBK20702.2 - 7.4e-50 170.1 26.8 2.2e-25 89.9 15.2 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 CBK20702.2 - 1.7e-45 154.9 0.0 1.6e-26 93.5 0.0 2.9 2 1 0 2 2 2 2 ABC transporter SMC_N PF02463.19 CBK20702.2 - 1.9e-08 34.0 2.2 0.0014 18.1 0.0 4.1 3 1 0 4 4 4 1 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 CBK20702.2 - 8.4e-05 22.6 3.4 0.087 12.9 0.1 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase DEAD PF00270.29 CBK20702.2 - 0.00019 21.3 0.0 0.088 12.6 0.0 2.7 2 1 0 2 2 2 1 DEAD/DEAH box helicase AAA_7 PF12775.7 CBK20702.2 - 0.00026 20.6 0.7 0.12 11.8 0.2 2.5 2 0 0 2 2 2 1 P-loop containing dynein motor region DUF87 PF01935.17 CBK20702.2 - 0.00033 20.8 5.2 0.26 11.4 0.1 2.5 2 0 0 2 2 2 2 Helicase HerA, central domain AAA_29 PF13555.6 CBK20702.2 - 0.00036 20.2 0.2 0.24 11.2 0.0 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain Dynamin_N PF00350.23 CBK20702.2 - 0.00077 19.6 0.4 0.073 13.1 0.0 3.1 3 0 0 3 3 3 1 Dynamin family RsgA_GTPase PF03193.16 CBK20702.2 - 0.00085 19.3 0.1 0.28 11.1 0.0 2.5 2 0 0 2 2 2 1 RsgA GTPase AAA_25 PF13481.6 CBK20702.2 - 0.0018 17.9 0.3 0.17 11.4 0.1 2.6 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 CBK20702.2 - 0.0023 18.3 0.7 0.27 11.6 0.4 3.5 2 1 1 3 3 3 1 AAA ATPase domain cobW PF02492.19 CBK20702.2 - 0.0039 16.8 0.9 0.072 12.7 0.0 2.4 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.6 CBK20702.2 - 0.0055 16.4 1.5 3.4 7.4 0.2 2.8 3 0 0 3 3 3 2 AAA domain Zeta_toxin PF06414.12 CBK20702.2 - 0.0062 15.8 0.9 0.099 11.9 0.1 2.3 2 0 0 2 2 2 1 Zeta toxin DnaB_C PF03796.15 CBK20702.2 - 0.0099 15.2 0.1 0.031 13.6 0.1 1.8 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain NB-ARC PF00931.22 CBK20702.2 - 0.01 15.1 0.6 0.7 9.0 0.0 2.5 2 1 0 2 2 2 1 NB-ARC domain ATP_bind_1 PF03029.17 CBK20702.2 - 0.011 15.6 3.8 1.2 8.9 1.3 2.4 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein T2SSE PF00437.20 CBK20702.2 - 0.012 14.7 0.0 1 8.4 0.0 2.5 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA PF00004.29 CBK20702.2 - 0.018 15.5 2.2 2.7 8.4 0.0 3.4 3 1 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) FtsK_SpoIIIE PF01580.18 CBK20702.2 - 0.02 14.3 0.4 6.7 6.0 0.2 2.5 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_22 PF13401.6 CBK20702.2 - 0.028 14.7 4.4 4.2 7.6 0.1 3.7 3 1 0 3 3 2 0 AAA domain TsaE PF02367.17 CBK20702.2 - 0.032 14.2 0.5 0.41 10.6 0.1 2.5 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Ploopntkinase3 PF18751.1 CBK20702.2 - 0.07 13.0 1.4 7.3 6.5 0.0 3.3 3 0 0 3 3 3 0 P-loop Nucleotide Kinase3 IstB_IS21 PF01695.17 CBK20702.2 - 0.078 12.7 1.2 12 5.6 0.0 3.7 4 0 0 4 4 4 0 IstB-like ATP binding protein AAA_23 PF13476.6 CBK20702.2 - 0.11 13.0 0.2 1.9 8.9 0.0 2.3 2 0 0 2 2 2 0 AAA domain MobB PF03205.14 CBK20702.2 - 0.11 12.4 0.9 1.5 8.7 0.1 2.4 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B NACHT PF05729.12 CBK20702.2 - 0.13 12.2 2.6 1.9 8.4 0.1 3.3 3 0 0 3 3 3 0 NACHT domain Pox_A32 PF04665.12 CBK20702.2 - 0.14 11.6 2.7 1.5 8.2 0.2 2.7 3 0 0 3 3 2 0 Poxvirus A32 protein TrwB_AAD_bind PF10412.9 CBK20702.2 - 0.2 10.5 0.6 13 4.5 0.1 2.3 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain Septin PF00735.18 CBK20702.2 - 0.33 10.2 1.0 8.9 5.5 0.1 2.2 2 0 0 2 2 2 0 Septin RNA_helicase PF00910.22 CBK20702.2 - 0.34 11.3 1.0 61 4.1 0.0 3.2 3 0 0 3 3 3 0 RNA helicase Pkinase PF00069.25 CBK20703.2 - 7.4e-42 143.5 0.0 9.4e-42 143.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBK20703.2 - 4.5e-34 117.9 0.0 6.4e-34 117.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CBK20703.2 - 3.2e-07 29.5 0.0 5e-07 28.9 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 CBK20703.2 - 0.013 14.5 0.0 0.021 13.8 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain ENTH PF01417.20 CBK20704.2 - 8.8e-14 51.6 0.0 1.3e-09 38.1 0.0 2.1 2 0 0 2 2 2 2 ENTH domain ANTH PF07651.16 CBK20704.2 - 0.00016 20.8 0.0 0.094 11.7 0.0 2.1 2 0 0 2 2 2 2 ANTH domain VHS PF00790.19 CBK20704.2 - 0.00082 19.2 0.0 0.0022 17.8 0.0 1.7 2 0 0 2 2 2 1 VHS domain DUF764 PF05561.11 CBK20704.2 - 0.0032 17.3 0.0 0.0061 16.4 0.0 1.4 1 0 0 1 1 1 1 Borrelia burgdorferi protein of unknown function (DUF764) HEAT PF02985.22 CBK20704.2 - 0.009 16.2 0.0 0.043 14.1 0.0 2.2 3 0 0 3 3 3 1 HEAT repeat Adaptin_N PF01602.20 CBK20704.2 - 0.028 13.0 0.1 1.8 7.1 0.1 2.0 2 0 0 2 2 2 0 Adaptin N terminal region Nucleoporin_FG PF13634.6 CBK20704.2 - 0.32 11.8 13.7 0.48 11.3 3.7 2.4 1 1 1 2 2 2 0 Nucleoporin FG repeat region PC_rep PF01851.22 CBK20705.2 - 5.6e-06 26.5 12.2 0.0093 16.4 0.3 4.6 5 0 0 5 5 5 2 Proteasome/cyclosome repeat HEAT_2 PF13646.6 CBK20705.2 - 9.2e-05 22.8 0.1 0.22 11.9 0.0 4.7 3 2 2 5 5 5 2 HEAT repeats ANAPC3 PF12895.7 CBK20705.2 - 0.0063 16.7 2.6 0.1 12.9 0.2 2.6 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 HEAT_2 PF13646.6 CBK20706.2 - 1.2e-09 38.4 0.1 2.2e-09 37.6 0.1 1.5 1 0 0 1 1 1 1 HEAT repeats HEAT PF02985.22 CBK20706.2 - 0.00013 22.0 0.1 1.9 9.0 0.0 3.3 3 0 0 3 3 3 2 HEAT repeat HEAT_EZ PF13513.6 CBK20706.2 - 0.98 10.0 5.5 7.9 7.1 0.1 3.1 2 1 1 3 3 3 0 HEAT-like repeat RRM_1 PF00076.22 CBK20708.2 - 9.2e-08 31.8 0.0 0.00013 21.7 0.0 2.8 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Red1 PF07964.11 CBK20708.2 - 0.02 13.1 4.4 0.027 12.7 4.4 1.1 1 0 0 1 1 1 0 Rec10 / Red1 RXT2_N PF08595.11 CBK20708.2 - 0.06 13.4 5.1 0.12 12.4 5.1 1.4 1 0 0 1 1 1 0 RXT2-like, N-terminal FAM176 PF14851.6 CBK20708.2 - 0.13 12.0 4.5 0.25 11.0 4.5 1.4 1 0 0 1 1 1 0 FAM176 family TFIIE-A_C PF11521.8 CBK20708.2 - 0.24 11.7 8.7 5 7.5 7.4 2.6 2 0 0 2 2 2 0 C-terminal general transcription factor TFIIE alpha Tim54 PF11711.8 CBK20708.2 - 0.72 8.6 6.3 0.96 8.2 6.3 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Metallophos PF00149.28 CBK20709.2 - 9.8e-21 75.2 0.0 1.4e-20 74.7 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase RuvX PF03652.15 CBK20710.2 - 2.5e-24 86.2 0.0 3e-24 85.9 0.0 1.1 1 0 0 1 1 1 1 Holliday junction resolvase TAXi_C PF14541.6 CBK20711.2 - 2.7e-18 66.3 0.0 5.9e-18 65.2 0.0 1.5 2 0 0 2 2 2 1 Xylanase inhibitor C-terminal Asp PF00026.23 CBK20711.2 - 2.8e-09 36.8 0.0 3.7e-09 36.4 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 CBK20711.2 - 0.02 15.1 1.2 0.035 14.4 1.2 1.4 1 0 0 1 1 1 0 Xylanase inhibitor N-terminal CBS PF00571.28 CBK20712.2 - 2.2e-28 98.5 0.4 2e-10 41.0 0.0 3.2 3 0 0 3 3 3 3 CBS domain Complex1_LYR PF05347.15 CBK20713.2 - 3.6e-05 23.7 0.0 6.8e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 Complex 1 protein (LYR family) UFD1 PF03152.14 CBK20714.2 - 6.8e-49 165.7 0.0 8.4e-49 165.4 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 CDC48_2 PF02933.17 CBK20714.2 - 1.9e-06 27.5 0.2 1.4e-05 24.8 0.2 2.1 2 0 0 2 2 2 1 Cell division protein 48 (CDC48), domain 2 eIF-1a PF01176.19 CBK20714.2 - 0.072 12.9 0.0 0.22 11.4 0.0 1.8 1 0 0 1 1 1 0 Translation initiation factor 1A / IF-1 DUF4134 PF13572.6 CBK20715.2 - 0.005 17.1 0.1 0.0066 16.7 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4134) COX7B PF05392.11 CBK20716.2 - 0.084 12.6 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 Cytochrome C oxidase chain VIIB Fibrillarin PF01269.17 CBK20717.2 - 1.1e-104 348.5 0.0 1.3e-104 348.3 0.0 1.0 1 0 0 1 1 1 1 Fibrillarin GCD14 PF08704.10 CBK20717.2 - 1.3e-05 25.0 0.1 2.6e-05 24.0 0.1 1.4 1 1 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit XPG_I PF00867.18 CBK20718.2 - 3.1e-19 69.1 0.0 5.4e-19 68.3 0.0 1.4 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.17 CBK20718.2 - 0.00026 21.4 0.0 0.00044 20.7 0.0 1.4 1 0 0 1 1 1 1 XPG N-terminal domain TPR_1 PF00515.28 CBK20718.2 - 0.0051 16.6 0.1 0.0092 15.8 0.1 1.4 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_14 PF13428.6 CBK20718.2 - 0.057 14.3 0.1 0.2 12.5 0.1 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_8 PF13181.6 CBK20718.2 - 0.14 12.5 0.1 0.28 11.5 0.1 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat DUF846 PF05832.12 CBK20719.2 - 3.1e-43 147.1 12.4 4e-43 146.8 12.4 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF846) GP41 PF00517.17 CBK20719.2 - 0.033 14.1 0.3 0.052 13.4 0.3 1.3 1 0 0 1 1 1 0 Retroviral envelope protein DUF5056 PF16479.5 CBK20719.2 - 0.1 12.8 0.1 0.1 12.8 0.1 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF5056) JTB PF05439.12 CBK20719.2 - 0.38 10.8 0.2 0.38 10.8 0.2 2.0 3 0 0 3 3 3 0 Jumping translocation breakpoint protein (JTB) DUF2784 PF10861.8 CBK20719.2 - 1.3 9.1 9.4 0.26 11.3 1.0 2.4 2 0 0 2 2 2 0 Protein of Unknown function (DUF2784) Bud13 PF09736.9 CBK20720.2 - 1.7e-39 135.5 13.0 3.1e-39 134.7 13.0 1.4 1 1 0 1 1 1 1 Pre-mRNA-splicing factor of RES complex Ribosomal_S8 PF00410.19 CBK20720.2 - 0.65 9.9 3.6 0.25 11.3 1.0 1.6 2 0 0 2 2 2 0 Ribosomal protein S8 DUF334 PF03904.13 CBK20720.2 - 5.5 6.5 8.0 7.2 6.1 8.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF334) ThiF PF00899.21 CBK20722.2 - 1.1e-91 306.5 0.0 2.9e-62 210.2 0.0 2.5 2 1 0 2 2 2 2 ThiF family UBA_e1_thiolCys PF10585.9 CBK20722.2 - 5.4e-71 239.5 0.1 1.1e-70 238.5 0.1 1.5 1 0 0 1 1 1 1 Ubiquitin-activating enzyme active site E1_FCCH PF16190.5 CBK20722.2 - 3.7e-26 91.1 0.0 9.9e-26 89.7 0.0 1.8 1 0 0 1 1 1 1 Ubiquitin-activating enzyme E1 FCCH domain E1_4HB PF16191.5 CBK20722.2 - 5.8e-18 64.8 0.0 2.1e-17 63.1 0.0 2.1 1 0 0 1 1 1 1 Ubiquitin-activating enzyme E1 four-helix bundle E1_UFD PF09358.10 CBK20722.2 - 2.2e-07 31.5 0.0 4.4e-07 30.5 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin fold domain Shikimate_DH PF01488.20 CBK20722.2 - 0.0084 16.2 0.9 2.1 8.4 0.1 2.4 2 0 0 2 2 2 2 Shikimate / quinate 5-dehydrogenase Plasmod_dom_1 PF09715.10 CBK20722.2 - 0.033 14.3 0.0 0.082 13.0 0.0 1.7 1 0 0 1 1 1 0 Plasmodium protein of unknown function (Plasmod_dom_1) Pyr_redox_2 PF07992.14 CBK20722.2 - 0.054 12.7 0.1 0.1 11.8 0.1 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Rhodanese PF00581.20 CBK20724.2 - 0.042 14.4 0.0 0.077 13.5 0.0 1.4 1 0 0 1 1 1 0 Rhodanese-like domain RNA_pol_L_2 PF13656.6 CBK20725.2 - 1e-26 92.5 0.0 1.2e-26 92.2 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.24 CBK20725.2 - 5.6e-09 35.3 0.0 6.8e-09 35.0 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Topoisom_bac PF01131.20 CBK20726.2 - 6.1e-91 305.5 0.0 7.7e-91 305.1 0.0 1.1 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.22 CBK20726.2 - 1.2e-17 64.0 0.0 2.1e-17 63.2 0.0 1.4 1 0 0 1 1 1 1 Toprim domain ADK_lid PF05191.14 CBK20726.2 - 0.83 9.7 3.3 2.1 8.4 0.1 2.8 2 0 0 2 2 2 0 Adenylate kinase, active site lid ACPS PF01648.20 CBK20727.2 - 4.7e-09 36.4 0.0 8.4e-09 35.6 0.0 1.4 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily Glyco_transf_49 PF13896.6 CBK20728.2 - 2.5e-21 76.4 1.9 4.3e-15 55.9 1.4 2.5 1 1 1 2 2 2 2 Glycosyl-transferase for dystroglycan Methyltr_RsmB-F PF01189.17 CBK20729.2 - 4.6e-33 114.5 0.1 3.7e-31 108.3 0.1 3.1 1 1 0 1 1 1 1 16S rRNA methyltransferase RsmB/F Zip PF02535.22 CBK20729.2 - 0.0047 16.2 0.9 0.0062 15.8 0.9 1.1 1 0 0 1 1 1 1 ZIP Zinc transporter FtsJ PF01728.19 CBK20729.2 - 0.025 14.7 0.0 0.063 13.4 0.0 1.7 1 0 0 1 1 1 0 FtsJ-like methyltransferase RNA_pol_Rpc4 PF05132.14 CBK20729.2 - 0.042 14.3 6.0 0.082 13.3 6.0 1.5 1 0 0 1 1 1 0 RNA polymerase III RPC4 Cytomega_UL84 PF06284.11 CBK20729.2 - 0.089 11.2 1.1 0.13 10.7 1.1 1.2 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein RGP PF03214.13 CBK20729.2 - 0.19 10.9 0.1 0.29 10.2 0.1 1.2 1 0 0 1 1 1 0 Reversibly glycosylated polypeptide RR_TM4-6 PF06459.12 CBK20729.2 - 0.22 11.3 16.2 0.36 10.6 16.2 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 GAGA_bind PF06217.12 CBK20729.2 - 0.29 11.4 5.1 0.5 10.6 5.1 1.3 1 0 0 1 1 1 0 GAGA binding protein-like family SLC12 PF03522.15 CBK20729.2 - 0.69 8.9 6.5 1.1 8.2 6.5 1.2 1 0 0 1 1 1 0 Solute carrier family 12 Hid1 PF12722.7 CBK20729.2 - 0.87 7.6 7.0 1.3 7.1 7.0 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein FGF-BP1 PF06473.12 CBK20729.2 - 1.2 9.0 10.7 2.1 8.1 10.7 1.3 1 0 0 1 1 1 0 FGF binding protein 1 (FGF-BP1) RNA_polI_A34 PF08208.11 CBK20729.2 - 1.9 8.5 18.6 3.9 7.5 18.6 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 Myb_DNA-binding PF00249.31 CBK20730.2 - 1.3e-13 50.9 12.2 2.2e-12 46.9 0.7 3.8 3 1 0 3 3 3 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 CBK20730.2 - 2.4e-06 27.7 8.6 1.3e-05 25.4 1.2 2.8 2 0 0 2 2 2 2 Myb-like DNA-binding domain LAP1C PF05609.12 CBK20730.2 - 0.45 9.5 5.4 0.59 9.2 5.4 1.2 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Myb_DNA-bind_7 PF15963.5 CBK20730.2 - 8 6.4 10.5 0.27 11.1 0.2 3.3 2 1 2 4 4 4 0 Myb DNA-binding like SPESP1 PF15754.5 CBK20730.2 - 9.5 5.3 12.4 0.042 13.0 2.2 1.9 2 0 0 2 2 2 0 Sperm equatorial segment protein 1 TRM13 PF05206.14 CBK20731.2 - 3.4e-55 187.4 2.5 4.2e-49 167.4 0.2 2.3 1 1 1 2 2 2 2 Methyltransferase TRM13 RNase_HII PF01351.18 CBK20731.2 - 1.4e-17 64.2 0.0 2.7e-17 63.3 0.0 1.5 1 0 0 1 1 1 1 Ribonuclease HII zf-TRM13_CCCH PF11722.8 CBK20731.2 - 1.9e-09 37.1 1.9 1.9e-09 37.1 1.9 3.0 3 0 0 3 3 3 1 CCCH zinc finger in TRM13 protein zf-U11-48K PF05253.12 CBK20731.2 - 3.9e-09 36.2 0.6 3.9e-09 36.2 0.6 2.3 2 0 0 2 2 2 1 U11-48K-like CHHC zinc finger Methyltransf_32 PF13679.6 CBK20731.2 - 0.00091 19.2 2.2 0.00091 19.2 2.2 2.3 2 1 0 2 2 2 1 Methyltransferase domain zf-C3Hc3H PF13891.6 CBK20731.2 - 0.021 15.2 0.3 0.021 15.2 0.3 3.0 3 0 0 3 3 3 0 Potential DNA-binding domain Methyltransf_12 PF08242.12 CBK20731.2 - 0.036 14.8 0.0 0.17 12.6 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase domain RNase_HII PF01351.18 CBK20732.2 - 2e-24 86.6 0.0 2.5e-24 86.3 0.0 1.1 1 0 0 1 1 1 1 Ribonuclease HII Rad51 PF08423.11 CBK20733.2 - 0.00028 20.2 0.0 0.00034 20.0 0.0 1.1 1 0 0 1 1 1 1 Rad51 Herpes_UL7 PF01677.16 CBK20733.2 - 0.091 12.5 0.5 0.14 11.9 0.5 1.2 1 0 0 1 1 1 0 Herpesvirus UL7 like CwfJ_C_1 PF04677.15 CBK20734.2 - 1.5e-27 95.9 0.1 3.3e-27 94.8 0.1 1.5 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 CwfJ_C_2 PF04676.14 CBK20734.2 - 7.3e-05 23.6 2.3 8.5e-05 23.4 0.6 2.0 2 0 0 2 2 2 1 Protein similar to CwfJ C-terminus 2 Phage_base_V PF04717.12 CBK20734.2 - 0.012 15.6 0.0 0.04 13.8 0.0 1.9 2 0 0 2 2 2 0 Type VI secretion system, phage-baseplate injector Pkinase PF00069.25 CBK20736.2 - 7.2e-66 222.2 0.0 8.4e-66 222.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBK20736.2 - 5.2e-31 107.9 0.0 6.5e-31 107.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 CBK20736.2 - 0.00046 19.2 0.4 0.00073 18.6 0.4 1.4 1 1 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 CBK20736.2 - 0.00059 19.3 0.0 0.00094 18.6 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CBK20736.2 - 0.0062 16.5 0.0 0.012 15.6 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 CBK20736.2 - 0.085 12.2 0.0 0.15 11.4 0.0 1.4 1 0 0 1 1 1 0 Kinase-like FTA2 PF13095.6 CBK20736.2 - 0.093 12.3 0.3 2.6 7.6 0.0 2.2 2 1 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 GCP_N_terminal PF17681.1 CBK20737.2 - 8.7e-37 127.4 0.6 1.3e-36 126.8 0.6 1.3 1 0 0 1 1 1 1 Gamma tubulin complex component N-terminal GCP_C_terminal PF04130.13 CBK20737.2 - 7e-22 78.3 10.7 1.1e-21 77.6 10.7 1.3 1 0 0 1 1 1 1 Gamma tubulin complex component C-terminal Pkinase PF00069.25 CBK20738.2 - 4.3e-53 180.4 0.0 9.4e-53 179.3 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBK20738.2 - 5.9e-30 104.4 0.0 1.4e-25 90.0 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase LSM PF01423.22 CBK20738.2 - 3e-14 52.5 0.1 6.7e-14 51.3 0.1 1.6 1 0 0 1 1 1 1 LSM domain APH PF01636.23 CBK20738.2 - 2.3e-05 24.5 0.0 0.0015 18.5 0.0 2.2 2 0 0 2 2 2 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 CBK20738.2 - 6.6e-05 22.0 0.1 0.00011 21.3 0.1 1.3 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 CBK20738.2 - 0.027 13.8 0.0 0.048 13.0 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 CBK20738.2 - 0.029 14.0 0.0 0.056 13.0 0.0 1.5 1 0 0 1 1 1 0 RIO1 family Pox_ser-thr_kin PF05445.11 CBK20738.2 - 0.097 11.6 0.0 0.17 10.8 0.0 1.4 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase SecY PF00344.20 CBK20739.2 - 5.6e-66 222.9 9.5 8e-66 222.4 9.5 1.2 1 0 0 1 1 1 1 SecY translocase Plug_translocon PF10559.9 CBK20739.2 - 1.2e-17 63.4 0.1 4.1e-17 61.7 0.1 2.0 1 0 0 1 1 1 1 Plug domain of Sec61p TMEM220 PF15071.6 CBK20739.2 - 0.35 11.7 3.0 9 7.1 0.5 3.1 2 0 0 2 2 2 0 Transmembrane family 220, helix DUF1430 PF07242.11 CBK20739.2 - 2.9 8.2 7.1 18 5.6 1.1 3.6 3 1 0 3 3 3 0 Protein of unknown function (DUF1430) Ribosomal_S8 PF00410.19 CBK20740.2 - 6.4e-21 74.6 0.0 1e-20 74.0 0.0 1.3 1 1 0 1 1 1 1 Ribosomal protein S8 Pribosyltran PF00156.27 CBK20741.2 - 6.1e-27 94.1 0.0 7.2e-27 93.9 0.0 1.1 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 CBK20741.2 - 0.16 11.4 0.1 0.71 9.3 0.1 1.8 1 1 1 2 2 2 0 Uracil phosphoribosyltransferase BPL_LplA_LipB PF03099.19 CBK20742.2 - 0.13 12.2 0.0 0.37 10.7 0.0 1.7 1 1 0 1 1 1 0 Biotin/lipoate A/B protein ligase family KH_6 PF15985.5 CBK20743.2 - 4.3e-11 43.0 1.4 9.5e-11 41.9 1.4 1.5 1 0 0 1 1 1 1 KH domain ECR1_N PF14382.6 CBK20743.2 - 3.5e-09 36.3 0.8 6.7e-09 35.4 0.1 1.8 2 0 0 2 2 2 1 Exosome complex exonuclease RRP4 N-terminal region CpcD PF01383.21 CBK20743.2 - 0.02 15.2 0.0 0.052 13.8 0.0 1.7 1 0 0 1 1 1 0 CpcD/allophycocyanin linker domain Archease PF01951.16 CBK20744.2 - 1.3e-35 122.7 0.0 1.6e-35 122.4 0.0 1.1 1 0 0 1 1 1 1 Archease protein family (MTH1598/TM1083) Ribosomal_L39 PF00832.20 CBK20745.2 - 1.9e-21 75.4 10.9 2.2e-21 75.2 10.9 1.1 1 0 0 1 1 1 1 Ribosomal L39 protein PTPlike_phytase PF14566.6 CBK20746.2 - 7.2e-30 104.2 0.2 7.2e-30 104.2 0.2 1.8 2 1 0 2 2 2 1 Inositol hexakisphosphate RecQ_Zn_bind PF16124.5 CBK20746.2 - 0.0027 18.4 0.8 0.0061 17.3 0.2 2.0 2 0 0 2 2 2 1 RecQ zinc-binding Y_phosphatase3 PF13350.6 CBK20746.2 - 0.092 12.7 0.2 0.48 10.4 0.0 2.0 1 1 0 2 2 2 0 Tyrosine phosphatase family DUF1647 PF07801.11 CBK20746.2 - 1.1 8.9 5.2 0.28 10.9 0.8 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1647) RRM_1 PF00076.22 CBK20749.2 - 0.00015 21.5 0.0 0.00056 19.7 0.0 2.0 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Rab5ip PF07019.12 CBK20750.2 - 4.6e-10 40.0 7.0 6e-10 39.6 7.0 1.2 1 0 0 1 1 1 1 Rab5-interacting protein (Rab5ip) PetG PF02529.15 CBK20750.2 - 5.6 6.9 7.3 2.4 8.1 0.5 2.4 1 1 1 2 2 2 0 Cytochrome B6-F complex subunit 5 Med27 PF11571.8 CBK20752.2 - 0.097 13.0 6.2 0.2 12.1 6.2 1.4 1 1 1 2 2 2 0 Mediator complex subunit 27 CFC PF09443.10 CBK20752.2 - 0.63 9.9 7.3 3.6 7.5 2.2 2.2 2 0 0 2 2 2 0 Cripto_Frl-1_Cryptic (CFC) AMP-binding PF00501.28 CBK20753.2 - 2.7e-42 144.9 0.0 3.8e-42 144.4 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme DnaJ PF00226.31 CBK20754.2 - 1.4e-25 89.2 1.4 1.6e-25 89.0 0.1 1.8 2 0 0 2 2 2 1 DnaJ domain zf-C2H2_jaz PF12171.8 CBK20754.2 - 7.6e-06 26.1 0.3 1.4e-05 25.2 0.3 1.5 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 CBK20754.2 - 0.00035 20.9 0.2 0.00078 19.8 0.2 1.6 1 0 0 1 1 1 1 Zinc-finger of C2H2 type BshC PF10079.9 CBK20754.2 - 0.00041 19.2 0.9 0.00056 18.8 0.9 1.3 1 0 0 1 1 1 1 Bacillithiol biosynthesis BshC zf-C2H2_4 PF13894.6 CBK20754.2 - 0.023 15.5 0.1 0.066 14.1 0.1 1.8 1 0 0 1 1 1 0 C2H2-type zinc finger RPT PF13446.6 CBK20754.2 - 0.026 14.4 0.0 0.089 12.7 0.0 1.9 2 0 0 2 2 2 0 A repeated domain in UCH-protein zf-C2H2_6 PF13912.6 CBK20754.2 - 0.049 13.6 0.2 0.096 12.7 0.2 1.4 1 0 0 1 1 1 0 C2H2-type zinc finger DUF4407 PF14362.6 CBK20754.2 - 1.1 8.6 13.0 1.7 8.0 13.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF1764 PF08576.10 CBK20754.2 - 2 9.4 10.9 1.9 9.4 9.0 2.0 1 1 1 2 2 2 0 Eukaryotic protein of unknown function (DUF1764) WBP-1 PF11669.8 CBK20754.2 - 2 9.1 4.3 1.1 9.9 0.2 2.3 1 1 1 2 2 2 0 WW domain-binding protein 1 Presenilin PF01080.17 CBK20754.2 - 3.6 6.3 5.6 4.4 6.0 5.6 1.2 1 0 0 1 1 1 0 Presenilin Ribosomal_S13 PF00416.22 CBK20755.2 - 3.2e-36 124.6 0.3 3.5e-36 124.4 0.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S13/S18 DUF2746 PF10874.8 CBK20755.2 - 0.0021 18.4 0.0 0.0027 18.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2746) Period_C PF12114.8 CBK20755.2 - 0.079 12.5 0.0 0.095 12.3 0.0 1.1 1 0 0 1 1 1 0 Period protein 2/3C-terminal region Vps16_C PF04840.12 CBK20756.2 - 3.6e-13 49.3 6.7 1.5e-12 47.3 6.7 1.9 1 1 0 1 1 1 1 Vps16, C-terminal region Mito_carr PF00153.27 CBK20757.2 - 3e-54 180.9 2.3 4.6e-19 68.1 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein NMD3 PF04981.13 CBK20758.2 - 9.3e-57 192.3 0.4 1.2e-56 191.9 0.4 1.1 1 0 0 1 1 1 1 NMD3 family CDC45 PF02724.14 CBK20760.2 - 0.00015 20.2 11.9 0.00015 20.2 11.9 1.1 1 0 0 1 1 1 1 CDC45-like protein ASD2 PF08687.11 CBK20760.2 - 0.00088 18.9 11.6 0.0012 18.5 11.6 1.1 1 0 0 1 1 1 1 Apx/Shroom domain ASD2 SPX PF03105.19 CBK20760.2 - 0.0063 16.5 18.0 0.0072 16.3 18.0 1.1 1 0 0 1 1 1 1 SPX domain Astro_capsid_p PF12226.8 CBK20760.2 - 0.033 13.4 11.7 0.045 12.9 11.7 1.2 1 0 0 1 1 1 0 Turkey astrovirus capsid protein Plasmodium_Vir PF05795.11 CBK20760.2 - 0.052 13.0 13.5 0.068 12.6 13.5 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein SURF2 PF05477.11 CBK20760.2 - 0.058 13.1 19.2 0.088 12.5 19.2 1.3 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) DUF4746 PF15928.5 CBK20760.2 - 0.24 10.8 7.2 0.3 10.5 7.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) NPR3 PF03666.13 CBK20760.2 - 0.25 10.1 15.6 0.39 9.4 15.6 1.4 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Presenilin PF01080.17 CBK20760.2 - 0.29 9.8 17.5 0.35 9.6 17.5 1.1 1 0 0 1 1 1 0 Presenilin SAPS PF04499.15 CBK20760.2 - 1.1 8.0 13.7 1.2 7.8 13.7 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein BUD22 PF09073.10 CBK20760.2 - 1.1 8.5 34.8 1.4 8.2 34.8 1.1 1 0 0 1 1 1 0 BUD22 V_ATPase_I PF01496.19 CBK20760.2 - 3.1 5.6 6.2 4 5.2 6.2 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family SLC12 PF03522.15 CBK20760.2 - 3.3 6.6 13.5 4.1 6.3 13.5 1.1 1 0 0 1 1 1 0 Solute carrier family 12 Macoilin PF09726.9 CBK20760.2 - 3.9 5.9 26.2 5 5.6 26.2 1.1 1 0 0 1 1 1 0 Macoilin family Nop14 PF04147.12 CBK20760.2 - 4.5 5.4 28.7 5.8 5.0 28.7 1.0 1 0 0 1 1 1 0 Nop14-like family MAJIN PF15077.6 CBK20760.2 - 5.1 6.8 10.1 7.9 6.2 10.1 1.2 1 0 0 1 1 1 0 Membrane-anchored junction protein Apt1 PF10351.9 CBK20760.2 - 6.1 5.6 30.7 7.6 5.3 30.7 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Neur_chan_memb PF02932.16 CBK20760.2 - 7.2 6.6 14.8 9.9 6.1 14.8 1.5 1 1 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Smg8_Smg9 PF10220.9 CBK20760.2 - 7.5 4.7 20.0 9.1 4.4 20.0 1.0 1 0 0 1 1 1 0 Smg8_Smg9 RAP1 PF07218.11 CBK20760.2 - 8.2 4.6 27.5 10 4.2 27.5 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Raftlin PF15250.6 CBK20760.2 - 9 4.9 14.6 11 4.7 14.6 1.1 1 0 0 1 1 1 0 Raftlin NOA36 PF06524.12 CBK20760.2 - 9.2 5.5 14.4 13 5.0 14.4 1.2 1 0 0 1 1 1 0 NOA36 protein Zip PF02535.22 CBK20760.2 - 9.8 5.3 11.6 15 4.7 11.6 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter Actin PF00022.19 CBK20761.2 - 2.6e-88 296.4 0.0 1.6e-87 293.8 0.0 1.8 1 1 0 1 1 1 1 Actin Kinesin PF00225.23 CBK20762.2 - 1.9e-103 345.9 0.8 2.7e-103 345.4 0.8 1.2 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 CBK20762.2 - 6.1e-22 78.2 0.0 7.3e-21 74.7 0.0 2.3 1 1 0 1 1 1 1 Microtubule binding AAA_22 PF13401.6 CBK20762.2 - 0.063 13.5 0.1 0.61 10.4 0.0 2.4 2 1 0 2 2 2 0 AAA domain Csm1_N PF18504.1 CBK20762.2 - 0.12 12.8 4.2 27 5.2 0.1 3.6 3 0 0 3 3 3 0 Csm1 N-terminal domain Med4 PF10018.9 CBK20762.2 - 0.36 10.5 4.0 1.4 8.5 2.4 2.3 2 0 0 2 2 2 0 Vitamin-D-receptor interacting Mediator subunit 4 DUF4200 PF13863.6 CBK20762.2 - 0.68 10.3 0.0 0.68 10.3 0.0 2.9 3 1 0 3 3 3 0 Domain of unknown function (DUF4200) Peptidase_C1 PF00112.23 CBK20763.2 - 9.8e-73 244.8 5.4 1.5e-72 244.2 5.4 1.3 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 CBK20763.2 - 5.2e-09 36.4 1.8 9.2e-09 35.6 1.8 1.4 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.15 CBK20763.2 - 0.00033 19.5 3.4 0.24 10.2 1.0 2.2 2 0 0 2 2 2 2 Peptidase C1-like family DUF3343 PF11823.8 CBK20763.2 - 0.034 13.6 1.0 5 6.7 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3343) DUF167 PF02594.16 CBK20764.2 - 0.018 15.2 0.0 0.039 14.1 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised ACR, YggU family COG1872 SepSecS PF05889.13 CBK20765.2 - 1.9e-123 412.0 0.0 2.3e-123 411.8 0.0 1.0 1 0 0 1 1 1 1 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS Beta_elim_lyase PF01212.21 CBK20765.2 - 0.026 13.8 0.0 0.033 13.5 0.0 1.2 1 0 0 1 1 1 0 Beta-eliminating lyase DUF2002 PF09400.10 CBK20765.2 - 0.12 12.4 0.0 0.26 11.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2002) WD40 PF00400.32 CBK20766.2 - 1.9e-43 145.6 26.2 1.1e-08 35.5 0.0 11.8 12 0 0 12 12 12 9 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBK20766.2 - 8.5e-18 64.5 1.6 7.6e-05 22.9 0.0 6.6 4 3 3 7 7 7 4 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 CBK20766.2 - 2.7e-07 30.2 3.5 0.083 12.2 0.1 3.8 3 1 1 4 4 4 3 WD40-like domain Utp12 PF04003.12 CBK20766.2 - 3.5e-07 30.5 0.2 9.7e-07 29.1 0.2 1.7 1 0 0 1 1 1 1 Dip2/Utp12 Family Nup160 PF11715.8 CBK20766.2 - 3e-05 22.9 4.1 0.73 8.4 0.0 6.0 6 1 1 7 7 7 1 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 CBK20766.2 - 0.0013 17.6 0.8 4.2 6.0 0.0 3.8 2 2 2 4 4 4 2 Nup133 N terminal like ELYS-bb PF16687.5 CBK20766.2 - 0.014 14.1 0.0 0.056 12.0 0.0 1.9 1 1 1 2 2 2 0 beta-propeller of ELYS nucleoporin Ge1_WD40 PF16529.5 CBK20766.2 - 0.017 14.1 0.5 27 3.6 0.0 4.3 3 1 2 5 5 5 0 WD40 region of Ge1, enhancer of mRNA-decapping protein TSA PF03249.13 CBK20767.2 - 0.01 14.7 0.0 0.014 14.3 0.0 1.1 1 0 0 1 1 1 0 Type specific antigen Peptidase_M3 PF01432.20 CBK20768.2 - 1.8e-37 129.7 0.0 2.4e-37 129.3 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M3 MADF_DNA_bdg PF10545.9 CBK20768.2 - 0.06 13.7 0.1 2.2 8.7 0.2 2.4 2 0 0 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like MORN PF02493.20 CBK20769.2 - 1.2e-07 31.2 7.1 0.00038 20.2 0.4 3.5 4 0 0 4 4 4 2 MORN repeat LRR_8 PF13855.6 CBK20769.2 - 0.022 14.5 8.1 0.56 10.0 1.3 3.8 4 1 0 4 4 4 0 Leucine rich repeat LRR_6 PF13516.6 CBK20769.2 - 0.37 11.0 4.4 4.4 7.6 0.1 3.6 3 0 0 3 3 3 0 Leucine Rich repeat Sad1_UNC PF07738.13 CBK20770.2 - 9.1e-08 32.2 0.0 0.026 14.5 0.0 4.5 3 0 0 3 3 3 2 Sad1 / UNC-like C-terminal TIG PF01833.24 CBK20770.2 - 0.00041 20.4 33.1 0.98 9.5 0.2 13.1 10 0 0 10 10 10 4 IPT/TIG domain FeoB_N PF02421.18 CBK20770.2 - 0.25 10.8 1.5 0.79 9.2 0.5 2.4 2 0 0 2 2 2 0 Ferrous iron transport protein B Big_3_5 PF16640.5 CBK20770.2 - 0.27 11.5 22.9 0.21 11.8 0.5 7.0 5 0 0 5 5 5 0 Bacterial Ig-like domain (group 3) Ras PF00071.22 CBK20771.2 - 7.9e-61 204.4 0.0 9e-61 204.2 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CBK20771.2 - 8.4e-35 119.6 0.0 1.1e-34 119.2 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CBK20771.2 - 7.8e-15 54.8 0.0 8.8e-15 54.6 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 CBK20771.2 - 0.00012 22.1 0.0 0.00016 21.7 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 CBK20771.2 - 0.00041 19.8 0.0 0.00047 19.6 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 CBK20771.2 - 0.22 11.4 0.1 17 5.3 0.0 2.4 1 1 2 3 3 3 0 RsgA GTPase UQ_con PF00179.26 CBK20772.2 - 2e-36 124.7 0.0 2.4e-36 124.4 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 CBK20772.2 - 6.2e-05 22.7 0.0 7.4e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 CBK20772.2 - 0.24 11.7 0.6 0.41 10.9 0.6 1.4 1 1 0 1 1 1 0 RWD domain BSMAP PF12280.8 CBK20773.2 - 0.01 16.1 1.1 0.014 15.6 1.1 1.2 1 0 0 1 1 1 0 Brain specific membrane anchored protein EptA_B_N PF08019.12 CBK20773.2 - 0.031 14.2 4.1 0.024 14.5 2.7 1.5 1 1 0 1 1 1 0 Phosphoethanolamine transferase EptA/EptB DUF1211 PF06736.11 CBK20773.2 - 0.29 11.6 4.4 0.34 11.4 2.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1211) DUF2976 PF11190.8 CBK20773.2 - 0.39 10.6 5.8 0.11 12.3 1.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2976) FeoB_associated PF12669.7 CBK20773.2 - 0.42 11.1 10.5 3.1 8.3 0.7 3.1 2 1 1 3 3 3 0 FeoB-associated Cys-rich membrane protein LMBR1 PF04791.16 CBK20774.2 - 8.5e-16 57.9 0.3 1.1e-15 57.6 0.3 1.0 1 0 0 1 1 1 1 LMBR1-like membrane protein DUF2207 PF09972.9 CBK20774.2 - 0.0013 17.5 1.6 0.0018 17.1 1.6 1.3 1 1 0 1 1 1 1 Predicted membrane protein (DUF2207) DUF334 PF03904.13 CBK20774.2 - 0.012 15.1 0.5 0.012 15.1 0.5 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF334) SPC25 PF06703.11 CBK20774.2 - 0.16 11.7 0.5 0.35 10.6 0.5 1.7 1 1 0 1 1 1 0 Microsomal signal peptidase 25 kDa subunit (SPC25) ThiF PF00899.21 CBK20776.2 - 3.5e-42 144.4 0.1 7.3e-42 143.4 0.1 1.5 1 0 0 1 1 1 1 ThiF family Sacchrp_dh_NADP PF03435.18 CBK20776.2 - 4e-05 23.9 3.0 0.00011 22.5 1.3 2.4 2 1 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain Sec8_exocyst PF04048.14 CBK20776.2 - 0.0068 16.3 1.3 0.53 10.2 0.2 3.0 3 0 0 3 3 3 1 Sec8 exocyst complex component specific domain UDPG_MGDP_dh_N PF03721.14 CBK20776.2 - 0.023 14.3 0.1 0.043 13.4 0.1 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain ApbA PF02558.16 CBK20776.2 - 0.033 13.8 0.0 0.076 12.7 0.0 1.7 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA AlaDh_PNT_C PF01262.21 CBK20776.2 - 0.035 13.4 0.1 0.42 9.9 0.0 2.2 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_3 PF01494.19 CBK20776.2 - 0.039 13.2 0.7 0.31 10.2 0.0 2.1 2 0 0 2 2 2 0 FAD binding domain 2-Hacid_dh_C PF02826.19 CBK20776.2 - 0.04 13.3 0.0 0.099 12.0 0.0 1.6 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Ribosomal_S26e PF01283.19 CBK20776.2 - 0.052 14.0 0.4 0.14 12.7 0.4 1.6 1 0 0 1 1 1 0 Ribosomal protein S26e NAD_binding_7 PF13241.6 CBK20776.2 - 0.067 13.6 0.5 0.57 10.7 0.2 2.6 2 1 0 2 2 2 0 Putative NAD(P)-binding Peptidase_S9 PF00326.21 CBK20777.2 - 5.9e-22 78.2 0.0 1.4e-20 73.7 0.0 2.0 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 CBK20777.2 - 1.2e-07 31.7 0.2 2.1e-07 30.9 0.2 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 CBK20777.2 - 1.4e-06 27.8 0.0 7.5e-05 22.1 0.0 2.1 1 1 1 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 CBK20777.2 - 2.9e-06 28.1 0.0 3.3e-06 27.9 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF2920 PF11144.8 CBK20777.2 - 0.048 12.8 0.0 0.073 12.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2920) Peptidase_S15 PF02129.18 CBK20777.2 - 0.066 12.8 0.0 0.67 9.5 0.0 2.0 1 1 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) Het-C PF07217.11 CBK20777.2 - 0.073 11.6 0.0 0.1 11.1 0.0 1.2 1 0 0 1 1 1 0 Heterokaryon incompatibility protein Het-C Esterase PF00756.20 CBK20777.2 - 0.094 12.3 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 Putative esterase PA28_beta PF02252.18 CBK20778.2 - 2.1e-21 76.1 0.0 2.2e-21 76.0 0.0 1.0 1 0 0 1 1 1 1 Proteasome activator pa28 beta subunit PRP38 PF03371.15 CBK20779.2 - 1.1e-38 132.9 0.0 2.1e-38 131.9 0.0 1.5 1 0 0 1 1 1 1 PRP38 family Plasmodium_Vir PF05795.11 CBK20779.2 - 0.055 12.9 8.8 0.092 12.1 8.8 1.3 1 0 0 1 1 1 0 Plasmodium vivax Vir protein TUDOR PF00567.24 CBK20779.2 - 0.071 13.1 0.1 0.42 10.7 0.0 2.2 2 0 0 2 2 2 0 Tudor domain DUF1899 PF08953.11 CBK20780.2 - 5e-16 58.3 0.0 1.4e-15 56.9 0.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF1899) WD40_4 PF16300.5 CBK20780.2 - 1.8e-12 47.0 0.2 3.3e-12 46.1 0.2 1.5 1 0 0 1 1 1 1 Type of WD40 repeat WD40 PF00400.32 CBK20780.2 - 8.4e-12 45.4 0.6 0.00071 20.3 0.0 4.6 5 0 0 5 5 5 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBK20780.2 - 5.8e-05 23.3 0.0 0.0031 17.8 0.0 2.8 2 1 1 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain CCDC-167 PF15188.6 CBK20780.2 - 0.0049 17.2 0.7 0.0082 16.5 0.7 1.3 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 167 Ge1_WD40 PF16529.5 CBK20780.2 - 0.23 10.4 0.1 3.6 6.5 0.3 2.7 1 1 2 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein VHP PF02209.19 CBK20781.2 - 4.3e-13 49.1 3.6 7.8e-13 48.3 3.6 1.4 1 0 0 1 1 1 1 Villin headpiece domain MqsA_antitoxin PF15731.5 CBK20781.2 - 0.034 14.2 0.0 0.036 14.2 0.0 1.2 1 0 0 1 1 1 0 Antitoxin component of bacterial toxin-antitoxin system, MqsA AbLIM_anchor PF16182.5 CBK20781.2 - 0.045 13.6 0.3 0.06 13.2 0.3 1.2 1 0 0 1 1 1 0 Putative adherens-junction anchoring region of AbLIM VGCC_beta4Aa_N PF12052.8 CBK20781.2 - 0.21 11.7 2.5 0.51 10.5 2.5 1.7 1 0 0 1 1 1 0 Voltage gated calcium channel subunit beta domain 4Aa N terminal LIM PF00412.22 CBK20782.2 - 8.8e-10 38.7 12.5 8.7e-09 35.5 6.6 2.4 2 0 0 2 2 2 2 LIM domain DUF1272 PF06906.11 CBK20782.2 - 0.021 14.9 9.5 0.029 14.4 1.7 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1272) zf-MYND PF01753.18 CBK20782.2 - 0.13 12.4 9.2 0.58 10.3 2.8 2.5 2 1 0 2 2 2 0 MYND finger zf_UBZ PF18439.1 CBK20782.2 - 2.8 7.6 8.0 9.4 5.9 0.2 3.4 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger VHP PF02209.19 CBK20783.2 - 1.6e-14 53.6 1.2 1.6e-14 53.6 1.2 2.4 2 0 0 2 2 2 1 Villin headpiece domain PAP2 PF01569.21 CBK20784.2 - 1.5e-06 28.0 5.8 3.7e-06 26.8 1.2 2.8 2 1 0 2 2 2 1 PAP2 superfamily DUF212 PF02681.14 CBK20784.2 - 0.03 14.4 0.1 0.065 13.4 0.1 1.6 1 1 1 2 2 2 0 Divergent PAP2 family ArfGap PF01412.18 CBK20785.2 - 3.2e-43 146.5 2.4 3.2e-43 146.5 2.4 1.9 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf HC2 PF07382.11 CBK20785.2 - 0.016 15.3 7.5 0.016 15.3 7.5 2.2 2 0 0 2 2 2 0 Histone H1-like nucleoprotein HC2 PBP1_TM PF14812.6 CBK20785.2 - 9.6 6.7 15.9 24 5.4 0.5 2.8 1 1 1 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF2871 PF11070.8 CBK20786.2 - 3.9 7.8 9.6 6.9 7.0 1.8 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2871) Aa_trans PF01490.18 CBK20787.2 - 6.9e-55 186.4 31.3 8.9e-55 186.0 31.3 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 CBK20787.2 - 2.1e-07 30.3 29.7 4.5e-07 29.3 29.7 1.6 1 1 0 1 1 1 1 Tryptophan/tyrosine permease family CENP-T_C PF15511.6 CBK20788.2 - 2.6e-08 34.0 0.1 3.2e-08 33.7 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TAF PF02969.17 CBK20788.2 - 5.2e-05 23.3 0.1 8.2e-05 22.7 0.1 1.5 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) Histone PF00125.24 CBK20788.2 - 6.4e-05 23.3 0.1 9.8e-05 22.7 0.1 1.4 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 CBK20788.2 - 0.00022 21.5 0.1 0.0003 21.1 0.1 1.4 1 1 0 1 1 1 1 CENP-S protein CBFD_NFYB_HMF PF00808.23 CBK20788.2 - 0.00093 19.4 0.1 0.0017 18.6 0.0 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 CBK20788.2 - 0.01 15.9 0.0 0.012 15.7 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 CBK20788.2 - 0.025 14.6 0.0 0.036 14.1 0.0 1.2 1 0 0 1 1 1 0 Bromodomain associated Histone PF00125.24 CBK20789.2 - 6.7e-53 178.5 2.8 7.5e-53 178.4 2.8 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 CBK20789.2 - 0.00011 22.5 0.1 0.00015 22.0 0.1 1.3 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 CBK20789.2 - 0.0005 20.2 0.1 0.00098 19.2 0.1 1.5 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold PAF PF15715.5 CBK20789.2 - 0.0011 19.6 0.9 0.0013 19.4 0.9 1.1 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CBFD_NFYB_HMF PF00808.23 CBK20789.2 - 0.019 15.2 0.0 0.039 14.2 0.0 1.5 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone EF-hand_6 PF13405.6 CBK20790.2 - 0.00019 21.1 0.4 0.00054 19.7 0.4 1.8 1 0 0 1 1 1 1 EF-hand domain EF-hand_1 PF00036.32 CBK20790.2 - 0.00029 20.1 0.1 0.00073 18.9 0.1 1.7 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.6 CBK20790.2 - 0.0003 21.2 1.2 0.00093 19.6 1.1 1.9 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_11 PF08976.11 CBK20790.2 - 0.00082 20.2 0.2 0.0076 17.1 0.2 2.3 2 0 0 2 2 2 1 EF-hand domain DUF3867 PF12983.7 CBK20790.2 - 0.0052 16.9 0.4 0.011 15.7 0.4 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF3867) Pkinase PF00069.25 CBK20791.2 - 8.4e-68 228.6 0.0 1.1e-67 228.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBK20791.2 - 1.2e-32 113.3 0.0 2.3e-32 112.3 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CBK20791.2 - 1.3e-06 27.9 0.0 2.1e-06 27.3 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 CBK20791.2 - 0.089 12.7 0.0 0.14 12.0 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family HSP70 PF00012.20 CBK20792.2 - 3.3e-18 65.2 0.0 5.8e-18 64.4 0.0 1.3 1 1 0 1 1 1 1 Hsp70 protein Actin PF00022.19 CBK20792.2 - 0.0013 17.4 0.0 0.0021 16.7 0.0 1.3 1 0 0 1 1 1 1 Actin HA2 PF04408.23 CBK20793.2 - 4.9e-19 68.6 0.0 1.3e-18 67.3 0.0 1.7 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 CBK20793.2 - 1.1e-15 57.7 0.0 2.6e-15 56.5 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 CBK20793.2 - 7.2e-12 45.6 0.0 3.3e-11 43.5 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 CBK20793.2 - 4.3e-07 29.9 0.1 1.1e-06 28.6 0.1 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 CBK20793.2 - 0.00028 21.1 0.1 0.00096 19.4 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 CBK20793.2 - 0.00059 19.6 0.0 0.001 18.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain Flavi_DEAD PF07652.14 CBK20793.2 - 0.00061 19.8 0.1 0.0011 18.9 0.1 1.4 1 0 0 1 1 1 1 Flavivirus DEAD domain AAA_19 PF13245.6 CBK20793.2 - 0.0042 17.4 0.1 0.0088 16.4 0.1 1.5 1 0 0 1 1 1 1 AAA domain ResIII PF04851.15 CBK20793.2 - 0.035 14.1 0.0 1.5 8.8 0.0 2.4 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit PhoH PF02562.16 CBK20793.2 - 0.066 12.6 0.1 0.13 11.7 0.1 1.4 1 0 0 1 1 1 0 PhoH-like protein AAA_23 PF13476.6 CBK20793.2 - 0.37 11.3 4.1 2.1 8.8 0.0 2.5 2 0 0 2 2 2 0 AAA domain Clat_adaptor_s PF01217.20 CBK20794.2 - 1.1e-44 151.8 7.7 1.2e-44 151.6 7.7 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain GDE_C PF06202.14 CBK20794.2 - 0.058 12.3 0.1 0.066 12.1 0.1 1.2 1 0 0 1 1 1 0 Amylo-alpha-1,6-glucosidase MYO10_CC PF16735.5 CBK20794.2 - 0.11 12.6 0.0 0.11 12.6 0.0 1.8 2 0 0 2 2 2 0 Unconventional myosin-X coiled coil domain EF-hand_13 PF17958.1 CBK20795.2 - 0.00095 18.9 0.0 0.1 12.4 0.0 2.6 2 0 0 2 2 2 1 EF-hand domain EF-hand_5 PF13202.6 CBK20795.2 - 0.0013 18.2 0.5 0.0029 17.0 0.5 1.7 1 0 0 1 1 1 1 EF hand EF-hand_1 PF00036.32 CBK20795.2 - 0.0014 18.1 0.5 0.004 16.6 0.5 1.8 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 CBK20795.2 - 0.0031 17.3 0.1 0.011 15.6 0.1 2.0 1 0 0 1 1 1 1 EF-hand domain EF-hand_7 PF13499.6 CBK20795.2 - 0.0089 16.5 0.2 0.024 15.1 0.0 1.9 2 0 0 2 2 2 1 EF-hand domain pair ATG27 PF09451.10 CBK20796.2 - 0.003 17.4 0.9 0.024 14.5 0.9 2.3 1 1 0 1 1 1 1 Autophagy-related protein 27 LapA_dom PF06305.11 CBK20796.2 - 0.11 12.4 0.4 0.2 11.5 0.4 1.3 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain EGF_2 PF07974.13 CBK20796.2 - 0.65 10.4 11.0 4.5 7.7 11.0 2.5 1 1 0 1 1 1 0 EGF-like domain Defensin_like PF10868.8 CBK20796.2 - 1.4 9.8 10.6 0.51 11.1 7.9 1.7 2 0 0 2 2 2 0 Cysteine-rich antifungal protein 2, defensin-like AP2 PF00847.20 CBK20797.2 - 0.14 12.4 1.0 0.26 11.5 1.0 1.5 1 0 0 1 1 1 0 AP2 domain TFIID_20kDa PF03847.13 CBK20798.2 - 6.7e-09 36.1 0.0 9.5e-09 35.6 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A Dus PF01207.17 CBK20799.2 - 1.6e-45 155.6 0.0 2.2e-45 155.1 0.0 1.1 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) zf-CCCH PF00642.24 CBK20799.2 - 1.8e-06 27.7 6.9 0.00032 20.5 0.2 2.9 3 0 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 CBK20799.2 - 0.00015 21.5 9.4 0.0027 17.5 0.4 3.6 3 0 0 3 3 3 2 CCCH-type zinc finger zf_CCCH_4 PF18345.1 CBK20799.2 - 0.94 9.6 7.4 0.78 9.9 0.6 2.8 2 0 0 2 2 2 0 Zinc finger domain Cyclin PF08613.11 CBK20800.2 - 5.4e-23 82.1 4.9 8e-23 81.6 4.9 1.2 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 CBK20800.2 - 1.8e-08 34.2 0.2 2.5e-08 33.7 0.2 1.2 1 0 0 1 1 1 1 Cyclin, N-terminal domain HMG_box_2 PF09011.10 CBK20802.2 - 1.3e-12 48.1 0.9 2.8e-12 47.1 0.9 1.6 1 0 0 1 1 1 1 HMG-box domain HMG_box PF00505.19 CBK20802.2 - 8.1e-12 45.4 0.3 1.8e-11 44.3 0.3 1.6 1 0 0 1 1 1 1 HMG (high mobility group) box zf-C2H2 PF00096.26 CBK20802.2 - 0.011 16.1 7.4 0.027 14.9 1.1 2.6 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2_8 PF15909.5 CBK20802.2 - 0.017 15.4 0.1 0.047 14.0 0.1 1.7 1 0 0 1 1 1 0 C2H2-type zinc ribbon zf-C2H2_aberr PF17017.5 CBK20802.2 - 0.031 14.4 1.8 0.051 13.7 0.2 2.0 2 0 0 2 2 2 0 Aberrant zinc-finger DUF4994 PF16385.5 CBK20802.2 - 0.065 13.2 0.2 0.17 11.8 0.2 1.8 1 0 0 1 1 1 0 Domain of unknown function Dpy19 PF10034.9 CBK20802.2 - 0.089 11.0 0.1 0.13 10.4 0.1 1.1 1 0 0 1 1 1 0 Q-cell neuroblast polarisation DUF2877 PF11392.8 CBK20802.2 - 0.12 13.1 0.3 0.28 11.9 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2877) DUF4047 PF13256.6 CBK20802.2 - 0.18 12.0 5.5 0.19 11.9 1.4 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4047) MCR_beta PF02241.18 CBK20802.2 - 0.18 11.4 0.0 0.3 10.6 0.0 1.2 1 0 0 1 1 1 0 Methyl-coenzyme M reductase beta subunit, C-terminal domain zf-C2H2_4 PF13894.6 CBK20802.2 - 1.2 10.1 5.8 0.39 11.7 1.2 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger zf-H2C2_5 PF13909.6 CBK20802.2 - 9.3 6.1 7.4 0.62 9.9 1.2 2.1 2 0 0 2 2 2 0 C2H2-type zinc-finger domain zf-C2H2 PF00096.26 CBK20803.2 - 2.6e-11 43.3 4.5 9.6e-07 28.9 0.4 2.8 3 0 0 3 3 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 CBK20803.2 - 1.6e-10 40.9 9.7 4.8e-06 26.8 0.1 3.1 3 0 0 3 3 3 2 Zinc-finger double domain zf_Hakai PF18408.1 CBK20803.2 - 4.6e-10 39.0 2.7 3.7e-05 23.3 0.2 2.4 2 0 0 2 2 2 2 C2H2 Hakai zinc finger domain zf-C2H2_4 PF13894.6 CBK20803.2 - 1e-07 32.2 3.9 0.00018 22.1 0.4 3.0 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_8 PF15909.5 CBK20803.2 - 0.0008 19.7 1.0 0.0063 16.8 0.5 1.9 1 1 0 1 1 1 1 C2H2-type zinc ribbon zf-C2H2_aberr PF17017.5 CBK20803.2 - 0.0012 19.0 3.3 0.26 11.4 0.6 2.1 1 1 1 2 2 2 2 Aberrant zinc-finger zf-C2H2_6 PF13912.6 CBK20803.2 - 0.0025 17.8 1.1 0.0025 17.8 1.1 2.9 3 0 0 3 3 3 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 CBK20803.2 - 0.0026 18.0 4.2 0.099 13.0 0.3 3.0 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding zf-C2HC_2 PF13913.6 CBK20803.2 - 0.0066 16.3 0.3 0.59 10.1 0.0 2.6 2 0 0 2 2 2 1 zinc-finger of a C2HC-type zf-met PF12874.7 CBK20803.2 - 0.015 15.6 5.1 1.4 9.4 0.0 3.0 3 0 0 3 3 3 0 Zinc-finger of C2H2 type CHORD PF04968.12 CBK20803.2 - 0.018 15.8 3.1 1.6 9.5 0.3 2.3 1 1 1 2 2 2 0 CHORD DUF1644 PF07800.12 CBK20803.2 - 0.038 14.1 2.6 0.048 13.7 2.2 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1644) Ogr_Delta PF04606.12 CBK20803.2 - 0.075 13.0 2.5 0.87 9.6 0.1 2.4 1 1 1 2 2 2 0 Ogr/Delta-like zinc finger zf-RRN7 PF11781.8 CBK20803.2 - 0.078 12.7 3.3 0.87 9.3 0.4 2.5 2 0 0 2 2 2 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 zf-Di19 PF05605.12 CBK20803.2 - 0.14 12.4 5.8 1.9 8.8 1.9 2.7 1 1 2 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding EF1G PF00647.19 CBK20805.2 - 6.2e-37 125.9 0.9 7.4e-37 125.7 0.1 1.5 2 0 0 2 2 2 1 Elongation factor 1 gamma, conserved domain SR-25 PF10500.9 CBK20805.2 - 0.25 10.9 6.5 0.38 10.3 6.5 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein ORC5_C PF14630.6 CBK20805.2 - 0.33 10.4 1.8 0.61 9.6 1.3 1.5 1 1 1 2 2 2 0 Origin recognition complex (ORC) subunit 5 C-terminus GST_C PF00043.25 CBK20805.2 - 2 8.7 4.5 2.4 8.4 0.0 2.4 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain Mo25 PF08569.11 CBK20806.2 - 2e-75 254.2 10.5 2.3e-75 254.0 10.5 1.0 1 0 0 1 1 1 1 Mo25-like SIL1 PF16782.5 CBK20806.2 - 1.1e-05 24.8 0.2 1.8e-05 24.1 0.2 1.3 1 0 0 1 1 1 1 Nucleotide exchange factor SIL1 TFIIA_gamma_N PF02268.16 CBK20806.2 - 0.05 13.6 0.0 0.14 12.2 0.0 1.7 1 0 0 1 1 1 0 Transcription initiation factor IIA, gamma subunit, helical domain Ribosomal_L5e PF17144.4 CBK20807.2 - 9.9e-77 256.5 1.3 2e-76 255.5 1.3 1.5 1 0 0 1 1 1 1 Ribosomal large subunit proteins 60S L5, and 50S L18 Ribosomal_L18_c PF14204.6 CBK20807.2 - 5e-31 107.5 5.9 1.1e-30 106.4 5.9 1.6 1 0 0 1 1 1 1 Ribosomal L18 C-terminal region STI1 PF17830.1 CBK20808.2 - 2.9e-17 62.3 6.1 8.9e-17 60.8 6.1 1.9 1 0 0 1 1 1 1 STI1 domain TPR_1 PF00515.28 CBK20808.2 - 0.0018 18.0 5.2 0.19 11.6 0.7 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat PMEI PF04043.15 CBK20808.2 - 0.0045 17.4 1.3 0.011 16.1 1.3 1.7 1 1 0 1 1 1 1 Plant invertase/pectin methylesterase inhibitor TPR_2 PF07719.17 CBK20808.2 - 0.0073 16.3 8.1 0.029 14.5 1.2 3.1 3 0 0 3 3 2 1 Tetratricopeptide repeat HipN PF18253.1 CBK20808.2 - 0.0087 15.7 0.0 0.019 14.7 0.0 1.5 1 0 0 1 1 1 1 Hsp70-interacting protein N N-terminal domain TPR_16 PF13432.6 CBK20808.2 - 0.018 15.7 6.6 0.2 12.3 0.5 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_9 PF13371.6 CBK20808.2 - 0.02 15.0 1.7 0.1 12.8 1.3 2.5 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.6 CBK20808.2 - 0.15 12.4 8.3 1 9.7 0.4 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF1682 PF07946.14 CBK20808.2 - 0.49 9.5 11.0 1 8.5 11.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) Endonuc_Holl PF10107.9 CBK20808.2 - 2.6 7.9 7.9 4.7 7.0 7.9 1.4 1 0 0 1 1 1 0 Endonuclease related to archaeal Holliday junction resolvase Pinin_SDK_memA PF04696.13 CBK20808.2 - 8.3 6.5 21.2 20 5.2 21.2 1.6 1 0 0 1 1 1 0 pinin/SDK/memA/ protein conserved region CybS PF05328.12 CBK20809.2 - 6.7e-10 38.8 0.5 8.5e-10 38.4 0.5 1.1 1 0 0 1 1 1 1 CybS, succinate dehydrogenase cytochrome B small subunit AMP-binding PF00501.28 CBK20810.2 - 1.2e-83 281.1 0.0 1.6e-83 280.7 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Cas_Cas2CT1978 PF09707.10 CBK20810.2 - 0.013 15.5 0.0 0.055 13.5 0.0 2.1 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Cas2CT1978) Thump_like PF18096.1 CBK20810.2 - 0.12 12.3 0.0 0.38 10.7 0.0 1.8 1 0 0 1 1 1 0 THUMP domain-like Myb_DNA-binding PF00249.31 CBK20813.2 - 8.2e-44 147.6 15.0 5.7e-15 55.2 2.0 3.2 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 CBK20813.2 - 6e-36 122.5 8.1 5.9e-14 52.1 0.0 3.3 1 1 2 3 3 3 3 Myb-like DNA-binding domain SLIDE PF09111.10 CBK20813.2 - 2.4e-12 46.9 0.1 0.00051 20.0 0.0 3.4 2 1 1 3 3 3 3 SLIDE Myb_DNA-bind_7 PF15963.5 CBK20813.2 - 3.6e-05 23.6 2.3 0.011 15.6 0.3 2.9 1 1 2 3 3 3 2 Myb DNA-binding like Rap1_C PF11626.8 CBK20813.2 - 0.00045 20.2 3.3 3 8.0 0.0 3.3 1 1 1 2 2 2 2 TRF2-interacting telomeric protein/Rap1 - C terminal domain SANT_DAMP1_like PF16282.5 CBK20813.2 - 0.0012 19.0 1.8 0.15 12.3 0.0 3.1 3 0 0 3 3 3 1 SANT/Myb-like domain of DAMP1 Myb_DNA-bind_2 PF08914.11 CBK20813.2 - 0.0014 18.7 0.1 7 6.9 0.0 3.4 2 1 1 3 3 3 1 Rap1 Myb domain Myb_DNA-bind_4 PF13837.6 CBK20813.2 - 0.013 15.8 10.6 0.78 10.2 0.9 3.9 4 1 0 4 4 4 0 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 CBK20813.2 - 0.067 13.5 1.3 0.93 9.9 1.1 2.7 3 0 0 3 3 3 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_5 PF13873.6 CBK20813.2 - 6.7 6.9 11.7 41 4.3 0.1 4.0 3 1 1 4 4 4 0 Myb/SANT-like DNA-binding domain STELLO PF03385.17 CBK20814.2 - 5.4e-14 51.8 0.1 1e-13 50.9 0.1 1.5 1 0 0 1 1 1 1 STELLO glycosyltransferases zf-B_box PF00643.24 CBK20815.2 - 0.00016 21.8 11.0 0.00016 21.8 11.0 2.4 2 0 0 2 2 2 1 B-box zinc finger CEBP_ZZ PF16366.5 CBK20815.2 - 0.00053 20.2 11.5 0.0025 18.0 10.5 2.3 2 1 0 2 2 2 1 Cytoplasmic polyadenylation element-binding protein ZZ domain zf-C3HC4_3 PF13920.6 CBK20815.2 - 0.012 15.4 10.3 0.012 15.4 10.3 2.5 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) REV PF00424.18 CBK20815.2 - 0.032 14.3 0.5 0.061 13.3 0.5 1.4 1 0 0 1 1 1 0 REV protein (anti-repression trans-activator protein) Cofilin_ADF PF00241.20 CBK20815.2 - 0.039 13.8 0.4 0.066 13.0 0.4 1.4 1 0 0 1 1 1 0 Cofilin/tropomyosin-type actin-binding protein zf-RING_5 PF14634.6 CBK20815.2 - 0.04 13.9 13.8 0.46 10.5 10.6 2.7 2 0 0 2 2 2 0 zinc-RING finger domain Zn_Tnp_IS91 PF14319.6 CBK20815.2 - 0.084 12.9 8.0 0.22 11.6 8.0 1.7 1 0 0 1 1 1 0 Transposase zinc-binding domain PHF5 PF03660.14 CBK20815.2 - 0.11 12.8 6.3 0.11 12.7 4.2 2.0 2 0 0 2 2 2 0 PHF5-like protein Transposase_24 PF03004.14 CBK20815.2 - 0.15 12.2 0.1 0.15 12.2 0.1 2.2 1 1 1 2 2 2 0 Plant transposase (Ptta/En/Spm family) ZZ PF00569.17 CBK20815.2 - 0.23 11.3 15.4 0.079 12.8 11.2 2.1 2 0 0 2 2 2 0 Zinc finger, ZZ type zf-UBP PF02148.19 CBK20815.2 - 0.23 11.8 8.8 0.59 10.5 8.8 1.7 1 0 0 1 1 1 0 Zn-finger in ubiquitin-hydrolases and other protein zf-C3HC4 PF00097.25 CBK20815.2 - 0.68 9.9 18.2 0.17 11.8 13.3 2.4 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) HD_3 PF13023.6 CBK20816.2 - 2.1e-42 144.8 0.0 2.6e-42 144.6 0.0 1.0 1 0 0 1 1 1 1 HD domain HD_2 PF12917.7 CBK20816.2 - 1.6e-15 57.3 0.0 2.2e-15 56.9 0.0 1.2 1 0 0 1 1 1 1 HD containing hydrolase-like enzyme HD PF01966.22 CBK20816.2 - 0.0032 17.7 0.0 0.016 15.4 0.0 1.9 1 1 0 1 1 1 1 HD domain RTC PF01137.21 CBK20817.2 - 8.3e-54 182.1 0.0 9.4e-54 181.9 0.0 1.0 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase RTC_insert PF05189.13 CBK20817.2 - 3.6e-29 101.3 0.0 5.4e-29 100.7 0.0 1.3 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain Pro_isomerase PF00160.21 CBK20818.2 - 1.6e-49 168.2 0.0 3.4e-49 167.1 0.0 1.6 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD zf-NOSIP PF15906.5 CBK20818.2 - 1.8e-09 37.6 0.1 6.3e-09 35.9 0.1 1.9 2 0 0 2 2 2 1 Zinc-finger of nitric oxide synthase-interacting protein Rtf2 PF04641.12 CBK20818.2 - 4e-09 36.2 11.3 5.4e-09 35.8 8.9 2.4 2 1 0 2 2 2 1 Rtf2 RING-finger U-box PF04564.15 CBK20818.2 - 0.019 15.1 0.0 0.078 13.2 0.0 2.1 1 1 1 2 2 2 0 U-box domain zf-Nse PF11789.8 CBK20818.2 - 0.072 12.9 0.1 0.32 10.9 0.1 2.1 1 1 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit DASH_Spc19 PF08287.11 CBK20818.2 - 0.089 12.7 7.0 0.15 12.0 7.0 1.2 1 0 0 1 1 1 0 Spc19 Rhamno_transf PF11316.8 CBK20819.2 - 0.034 13.5 0.0 0.038 13.4 0.0 1.1 1 0 0 1 1 1 0 Putative rhamnosyl transferase FHA PF00498.26 CBK20820.2 - 2e-19 69.7 0.0 4.6e-19 68.5 0.0 1.7 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 CBK20820.2 - 1.1e-07 32.1 0.1 0.0092 16.3 0.0 2.7 1 1 2 3 3 3 2 Inner membrane component of T3SS, cytoplasmic domain Peptidase_C13 PF01650.18 CBK20821.2 - 2.1e-10 40.5 3.3 3.1e-10 40.0 3.3 1.2 1 0 0 1 1 1 1 Peptidase C13 family TCTP PF00838.17 CBK20821.2 - 0.0042 17.5 0.2 0.009 16.4 0.2 1.6 1 0 0 1 1 1 1 Translationally controlled tumour protein FixQ PF05545.11 CBK20822.2 - 0.033 14.1 2.1 0.034 14.1 0.0 2.0 2 0 0 2 2 2 0 Cbb3-type cytochrome oxidase component FixQ EGF PF00008.27 CBK20822.2 - 0.12 12.7 4.5 0.28 11.5 4.5 1.6 1 0 0 1 1 1 0 EGF-like domain EGF_Tenascin PF18720.1 CBK20822.2 - 0.13 12.3 4.8 0.39 10.8 4.8 1.8 1 0 0 1 1 1 0 Tenascin EGF domain EGF_2 PF07974.13 CBK20822.2 - 1.2 9.6 7.6 2.5 8.5 7.6 1.6 1 0 0 1 1 1 0 EGF-like domain Pkinase PF00069.25 CBK20823.2 - 2.9e-25 89.2 0.0 3.6e-25 88.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBK20823.2 - 3.4e-12 46.2 0.0 4e-12 46.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CBK20823.2 - 4.6e-06 25.7 0.0 5.6e-06 25.4 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Ribosomal_S4 PF00163.19 CBK20823.2 - 0.057 14.3 0.3 0.78 10.7 0.2 2.3 2 0 0 2 2 2 0 Ribosomal protein S4/S9 N-terminal domain Kinase-like PF14531.6 CBK20823.2 - 0.09 12.1 0.0 1.3 8.3 0.0 2.0 1 1 1 2 2 2 0 Kinase-like Scramblase PF03803.15 CBK20824.2 - 3.6e-52 176.9 0.0 5.2e-52 176.3 0.0 1.2 1 0 0 1 1 1 1 Scramblase Nuc_sug_transp PF04142.15 CBK20825.2 - 3.9e-95 318.6 22.1 4.4e-95 318.5 22.1 1.0 1 0 0 1 1 1 1 Nucleotide-sugar transporter EamA PF00892.20 CBK20825.2 - 2.1e-10 40.9 33.1 3.1e-08 33.9 4.7 2.4 2 1 0 2 2 2 2 EamA-like transporter family UAA PF08449.11 CBK20825.2 - 1.4e-05 24.4 22.1 3.5e-05 23.2 19.3 3.1 1 1 0 1 1 1 1 UAA transporter family TPT PF03151.16 CBK20825.2 - 0.031 13.6 19.0 0.034 13.5 1.3 2.2 1 1 1 2 2 2 0 Triose-phosphate Transporter family TM_helix PF05552.12 CBK20825.2 - 0.04 13.9 4.3 1 9.4 3.9 2.7 2 0 0 2 2 2 0 Conserved TM helix DUF2663 PF10864.8 CBK20825.2 - 6.5 7.2 13.0 0.71 10.3 0.1 3.4 3 1 0 3 3 3 0 Protein of unknown function (DUF2663) VPS13 PF16908.5 CBK20826.2 - 6e-44 150.6 10.5 1.6e-23 83.7 0.0 3.5 4 0 0 4 4 4 2 Vacuolar sorting-associated protein 13, N-terminal Chorein_N PF12624.7 CBK20826.2 - 3.3e-36 123.9 1.8 3.3e-36 123.9 1.8 2.8 2 0 0 2 2 2 1 N-terminal region of Chorein or VPS13 VPS13_mid_rpt PF16910.5 CBK20826.2 - 1.2e-19 70.7 7.0 2.5e-19 69.7 1.8 4.1 4 0 0 4 4 4 1 Repeating coiled region of VPS13 VPS13_C PF16909.5 CBK20827.2 - 4.4e-63 212.3 7.4 4.7e-58 195.9 0.4 2.5 2 0 0 2 2 2 2 Vacuolar-sorting-associated 13 protein C-terminal PX PF00787.24 CBK20827.2 - 0.003 17.5 0.8 0.0066 16.4 0.8 1.6 1 0 0 1 1 1 1 PX domain ATG_C PF09333.11 CBK20827.2 - 0.026 14.8 0.1 0.62 10.5 0.1 2.8 3 0 0 3 3 3 0 Autophagy-related protein C terminal domain He_PIG PF05345.12 CBK20828.2 - 1.3e-26 92.6 48.2 1e-06 28.8 1.7 8.7 8 0 0 8 8 8 7 Putative Ig domain S-AdoMet_synt_C PF02773.16 CBK20829.2 - 2.8e-69 231.4 0.1 8.3e-69 229.9 0.0 1.8 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M PF02772.16 CBK20829.2 - 4.2e-48 162.6 0.0 1.1e-47 161.2 0.0 1.7 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.20 CBK20829.2 - 4.7e-43 145.9 0.3 4.7e-43 145.9 0.3 1.6 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, N-terminal domain AdoMet_Synthase PF01941.19 CBK20829.2 - 0.025 13.4 0.7 1.8 7.2 0.1 2.2 2 0 0 2 2 2 0 S-adenosylmethionine synthetase (AdoMet synthetase) WW PF00397.26 CBK20830.2 - 0.00025 21.0 2.1 0.00038 20.5 2.1 1.3 1 0 0 1 1 1 1 WW domain Acyltransferase PF01553.21 CBK20831.2 - 2.3e-21 75.8 0.0 5.2e-21 74.7 0.0 1.6 1 0 0 1 1 1 1 Acyltransferase AhpC-TSA PF00578.21 CBK20832.2 - 5.3e-37 126.5 0.0 7.1e-37 126.1 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 CBK20832.2 - 1.5e-12 47.5 0.0 2e-12 47.0 0.0 1.1 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.9 CBK20832.2 - 1.1e-10 41.2 0.0 2.2e-10 40.2 0.0 1.5 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin PGK PF00162.19 CBK20833.2 - 3.6e-151 503.4 2.8 4.1e-151 503.2 2.8 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase GCP_C_terminal PF04130.13 CBK20834.2 - 0.043 13.3 0.0 0.053 13.0 0.0 1.1 1 0 0 1 1 1 0 Gamma tubulin complex component C-terminal Cullin PF00888.22 CBK20836.2 - 2.7e-11 42.8 1.3 7e-11 41.5 0.1 2.0 2 0 0 2 2 2 1 Cullin family HlyIII PF03006.20 CBK20836.2 - 0.0035 17.1 0.3 0.0059 16.3 0.3 1.3 1 0 0 1 1 1 1 Haemolysin-III related Ribosomal_S25 PF03297.15 CBK20836.2 - 0.048 13.9 0.0 0.15 12.3 0.0 1.8 1 0 0 1 1 1 0 S25 ribosomal protein Ribosomal_S13 PF00416.22 CBK20837.2 - 3.2e-36 124.6 0.3 3.5e-36 124.4 0.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S13/S18 DUF2746 PF10874.8 CBK20837.2 - 0.0021 18.4 0.0 0.0027 18.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2746) Period_C PF12114.8 CBK20837.2 - 0.079 12.5 0.0 0.095 12.3 0.0 1.1 1 0 0 1 1 1 0 Period protein 2/3C-terminal region SUR7 PF06687.12 CBK20838.2 - 0.053 13.2 0.0 0.082 12.5 0.0 1.3 1 0 0 1 1 1 0 SUR7/PalI family Tricorn_C1 PF14684.6 CBK20838.2 - 0.16 12.0 0.5 0.74 9.9 0.1 2.2 2 0 0 2 2 2 0 Tricorn protease C1 domain Lipase_3 PF01764.25 CBK20839.2 - 2.3e-11 43.8 0.0 6.7e-11 42.2 0.0 1.8 1 1 0 1 1 1 1 Lipase (class 3) Lactamase_B_3 PF13483.6 CBK20840.2 - 6e-17 62.0 0.0 7.9e-17 61.6 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_2 PF12706.7 CBK20840.2 - 2.3e-12 46.8 0.0 3.2e-12 46.4 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 CBK20840.2 - 0.00064 19.8 1.4 0.0016 18.5 1.1 1.9 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily zf-H2C2_5 PF13909.6 CBK20842.2 - 4.3e-24 83.9 19.8 1.2e-05 24.9 0.2 5.6 5 0 0 5 5 5 5 C2H2-type zinc-finger domain zf-H2C2_2 PF13465.6 CBK20842.2 - 8.2e-21 73.4 38.1 2.1e-06 27.9 0.4 7.1 8 0 0 8 8 8 4 Zinc-finger double domain zf-C2H2 PF00096.26 CBK20842.2 - 3.2e-18 65.1 35.7 2.4e-05 24.6 0.7 5.8 6 0 0 6 6 6 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CBK20842.2 - 1e-08 35.3 28.3 0.17 12.8 0.6 5.6 5 0 0 5 5 5 5 C2H2-type zinc finger OrsD PF12013.8 CBK20842.2 - 0.00019 21.8 18.5 4.8 7.7 0.1 5.3 3 2 2 5 5 5 5 Orsellinic acid/F9775 biosynthesis cluster protein D zf-C2H2_8 PF15909.5 CBK20842.2 - 0.045 14.0 15.5 0.33 11.3 2.3 4.1 2 1 3 5 5 5 0 C2H2-type zinc ribbon zf-C2H2_aberr PF17017.5 CBK20842.2 - 0.056 13.6 13.9 1.2 9.3 0.5 4.3 4 1 0 4 4 4 0 Aberrant zinc-finger FOXP-CC PF16159.5 CBK20842.2 - 0.27 11.9 10.1 13 6.4 0.1 4.6 2 1 3 5 5 5 0 FOXP coiled-coil domain zf-C2H2_11 PF16622.5 CBK20842.2 - 4 7.3 9.6 4.8 7.0 0.9 3.5 3 0 0 3 3 3 0 zinc-finger C2H2-type DUF711 PF05167.12 CBK20843.2 - 7.8e-10 38.2 0.8 8e-10 38.2 0.8 1.1 1 0 0 1 1 1 1 Uncharacterised ACR (DUF711) TadZ_N PF16968.5 CBK20843.2 - 0.0061 16.3 0.0 0.0082 15.8 0.0 1.2 1 0 0 1 1 1 1 Pilus assembly protein TadZ N-terminal Phage_HK97_TLTM PF06120.11 CBK20843.2 - 0.007 15.6 0.0 0.0081 15.4 0.0 1.1 1 0 0 1 1 1 1 Tail length tape measure protein DUF4885 PF16226.5 CBK20843.2 - 0.11 11.6 0.1 0.14 11.1 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4885) Spore_YpjB PF09577.10 CBK20843.2 - 0.12 12.1 0.1 0.17 11.7 0.1 1.2 1 0 0 1 1 1 0 Sporulation protein YpjB (SpoYpjB) Complex1_LYR PF05347.15 CBK20843.2 - 0.19 11.8 0.2 4 7.6 0.0 2.2 2 0 0 2 2 2 0 Complex 1 protein (LYR family) DUF711 PF05167.12 CBK20844.2 - 5.2e-36 124.4 0.0 6.5e-36 124.1 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised ACR (DUF711) IHO1 PF15771.5 CBK20845.2 - 0.93 8.2 8.4 1.3 7.7 8.4 1.2 1 0 0 1 1 1 0 Interactor of HORMAD1 protein 1 Ribosomal_L35Ae PF01247.18 CBK20846.2 - 1.4e-34 118.1 1.7 1.6e-34 118.0 1.7 1.0 1 0 0 1 1 1 1 Ribosomal protein L35Ae Bromodomain PF00439.25 CBK20847.2 - 2.2e-17 62.9 0.8 5e-17 61.7 0.5 1.8 2 0 0 2 2 2 1 Bromodomain Acetyltransf_10 PF13673.7 CBK20847.2 - 5.3e-09 36.1 0.1 9.4e-09 35.3 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 CBK20847.2 - 4.5e-08 33.3 0.0 7.6e-08 32.6 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 CBK20847.2 - 9.2e-06 26.0 0.2 1.8e-05 25.1 0.2 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 CBK20847.2 - 0.054 13.6 0.7 0.11 12.6 0.7 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Y_phosphatase2 PF03162.13 CBK20848.2 - 4.4e-35 120.7 0.5 4.8e-35 120.6 0.5 1.0 1 0 0 1 1 1 1 Tyrosine phosphatase family SAM_decarbox PF01536.16 CBK20848.2 - 0.042 12.9 0.0 0.055 12.5 0.0 1.1 1 0 0 1 1 1 0 Adenosylmethionine decarboxylase zf-C3HC4_3 PF13920.6 CBK20849.2 - 5.7e-07 29.3 13.1 5.7e-07 29.3 13.1 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CBK20849.2 - 6.2e-06 26.0 14.8 1.6e-05 24.7 14.8 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 CBK20849.2 - 2.1e-05 24.2 13.5 2.1e-05 24.2 13.5 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CBK20849.2 - 4.1e-05 23.8 13.2 4.1e-05 23.8 13.2 2.1 2 0 0 2 2 2 1 Ring finger domain Prok-RING_4 PF14447.6 CBK20849.2 - 4.1e-05 23.3 11.2 9.8e-05 22.1 11.2 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-rbx1 PF12678.7 CBK20849.2 - 0.00016 21.9 8.0 0.00043 20.5 8.0 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 CBK20849.2 - 0.00054 19.9 13.3 0.00054 19.9 13.3 2.6 2 1 1 3 3 3 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 CBK20849.2 - 0.0011 19.0 10.5 0.0011 19.0 10.5 2.1 2 0 0 2 2 2 1 RING-type zinc-finger zf-ANAPC11 PF12861.7 CBK20849.2 - 0.0011 18.9 3.0 0.0024 17.9 3.0 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_6 PF14835.6 CBK20849.2 - 0.0025 17.7 3.2 0.0025 17.7 3.2 1.8 2 0 0 2 2 2 1 zf-RING of BARD1-type protein zf-Nse PF11789.8 CBK20849.2 - 0.043 13.6 8.6 0.079 12.8 8.6 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4_4 PF15227.6 CBK20849.2 - 9.1 6.5 21.2 0.22 11.7 10.8 3.1 2 2 1 3 3 3 0 zinc finger of C3HC4-type, RING AAA PF00004.29 CBK20850.2 - 9e-36 123.2 0.0 3e-35 121.5 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 CBK20850.2 - 1.9e-05 25.1 0.3 0.0011 19.4 0.0 3.0 1 1 0 3 3 3 1 AAA ATPase domain AAA_lid_3 PF17862.1 CBK20850.2 - 5.6e-05 22.9 0.1 0.29 11.0 0.0 2.6 2 0 0 2 2 2 2 AAA+ lid domain AAA_5 PF07728.14 CBK20850.2 - 0.0011 19.0 0.0 0.0024 17.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) RNA_helicase PF00910.22 CBK20850.2 - 0.0021 18.4 0.0 0.0047 17.3 0.0 1.7 1 0 0 1 1 1 1 RNA helicase AAA_22 PF13401.6 CBK20850.2 - 0.0029 17.9 0.9 0.38 11.0 0.0 3.5 2 1 2 4 4 4 1 AAA domain AAA_2 PF07724.14 CBK20850.2 - 0.0034 17.5 0.0 0.006 16.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) Rad17 PF03215.15 CBK20850.2 - 0.0097 15.8 0.0 0.05 13.5 0.0 2.2 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_14 PF13173.6 CBK20850.2 - 0.013 15.5 0.0 0.027 14.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 CBK20850.2 - 0.018 14.9 0.0 0.59 10.0 0.0 2.6 1 1 1 2 2 2 0 NACHT domain AAA_29 PF13555.6 CBK20850.2 - 0.021 14.6 0.0 0.048 13.4 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF815 PF05673.13 CBK20850.2 - 0.033 13.3 0.0 0.052 12.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_7 PF12775.7 CBK20850.2 - 0.043 13.3 0.0 0.1 12.1 0.0 1.7 1 1 0 1 1 1 0 P-loop containing dynein motor region RsgA_GTPase PF03193.16 CBK20850.2 - 0.05 13.5 0.0 0.098 12.6 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase ABC_tran PF00005.27 CBK20850.2 - 0.067 13.7 0.0 0.17 12.4 0.0 1.7 1 0 0 1 1 1 0 ABC transporter AAA_33 PF13671.6 CBK20850.2 - 0.073 13.2 0.0 0.16 12.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain TIP49 PF06068.13 CBK20850.2 - 0.076 12.2 0.0 0.12 11.5 0.0 1.2 1 0 0 1 1 1 0 TIP49 P-loop domain IstB_IS21 PF01695.17 CBK20850.2 - 0.089 12.5 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein RuvB_N PF05496.12 CBK20850.2 - 0.13 12.0 0.0 0.25 11.1 0.0 1.5 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_23 PF13476.6 CBK20850.2 - 0.19 12.2 0.0 0.35 11.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 CBK20850.2 - 0.19 11.4 0.1 1.2 8.9 0.1 2.0 1 1 0 1 1 1 0 Sigma-54 interaction domain Bax1-I PF01027.20 CBK20851.2 - 3.7e-27 95.5 21.3 4.2e-27 95.3 21.3 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 DUF4131 PF13567.6 CBK20851.2 - 0.43 10.2 2.9 0.85 9.3 2.9 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) Bax1-I PF01027.20 CBK20852.2 - 2.6e-06 27.4 4.7 3e-06 27.2 4.7 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 DUF2207 PF09972.9 CBK20852.2 - 0.1 11.4 1.4 0.093 11.5 1.4 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) OST3_OST6 PF04756.13 CBK20852.2 - 0.14 11.5 3.5 0.15 11.4 3.5 1.0 1 0 0 1 1 1 0 OST3 / OST6 family, transporter family FtsX PF02687.21 CBK20852.2 - 0.33 11.5 6.9 0.5 10.9 6.9 1.2 1 0 0 1 1 1 0 FtsX-like permease family Sigma_reg_N PF13800.6 CBK20852.2 - 5.2 7.4 7.7 5.6 7.3 0.7 2.1 2 0 0 2 2 2 0 Sigma factor regulator N-terminal zf-RING_2 PF13639.6 CBK20853.2 - 8.2e-15 54.9 5.0 1.6e-14 53.9 5.0 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 CBK20853.2 - 2.3e-12 46.4 1.4 2.3e-12 46.4 1.4 2.1 3 0 0 3 3 2 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 CBK20853.2 - 3.1e-10 39.7 6.1 5e-10 39.1 6.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) PA PF02225.22 CBK20853.2 - 6.9e-10 38.8 0.0 1.1e-09 38.2 0.0 1.3 1 0 0 1 1 1 1 PA domain zf-C3HC4 PF00097.25 CBK20853.2 - 1.6e-08 34.3 4.7 2.7e-08 33.5 4.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CBK20853.2 - 2.9e-08 33.6 3.7 8e-08 32.2 0.7 2.3 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 CBK20853.2 - 3.4e-08 33.3 3.5 5.4e-08 32.7 3.5 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.7 CBK20853.2 - 6.6e-08 32.7 4.3 1.6e-07 31.5 4.3 1.6 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_3 PF13920.6 CBK20853.2 - 3.8e-06 26.6 2.8 6.2e-06 26.0 2.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 CBK20853.2 - 9.4e-06 25.6 1.7 3.7e-05 23.7 1.7 1.9 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_ribbon_17 PF17120.5 CBK20853.2 - 0.00011 21.7 2.9 0.0002 20.9 2.9 1.4 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type Prok-RING_4 PF14447.6 CBK20853.2 - 0.00016 21.4 2.9 0.00029 20.6 2.9 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 CBK20853.2 - 0.0069 16.5 3.8 0.015 15.4 3.8 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.6 CBK20853.2 - 0.011 15.5 3.1 0.019 14.7 3.1 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain FANCL_C PF11793.8 CBK20853.2 - 0.019 15.1 2.7 0.064 13.4 2.4 2.0 1 1 0 1 1 1 0 FANCL C-terminal domain TMEM43 PF07787.12 CBK20853.2 - 0.027 13.9 0.1 0.036 13.5 0.1 1.2 1 0 0 1 1 1 0 Transmembrane protein 43 Prok-RING_1 PF14446.6 CBK20853.2 - 0.03 14.2 4.8 0.53 10.3 1.5 2.3 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 RINGv PF12906.7 CBK20853.2 - 0.039 14.1 2.2 0.1 12.7 2.2 1.7 1 1 0 1 1 1 0 RING-variant domain zf-RING-like PF08746.11 CBK20853.2 - 0.046 14.0 3.4 0.078 13.3 3.4 1.4 1 0 0 1 1 1 0 RING-like domain PHD PF00628.29 CBK20853.2 - 0.065 13.1 3.2 0.15 12.0 3.2 1.6 1 1 0 1 1 1 0 PHD-finger zf-Nse PF11789.8 CBK20853.2 - 0.21 11.4 2.9 0.43 10.4 2.9 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-C3H2C3 PF17122.5 CBK20853.2 - 0.9 9.6 4.9 2.2 8.4 4.9 1.7 1 1 0 1 1 1 0 Zinc-finger Collagen PF01391.18 CBK20854.2 - 7.9e-29 99.2 110.0 2.4e-08 33.6 26.0 4.3 1 1 3 4 4 4 4 Collagen triple helix repeat (20 copies) DNA_pol_B_2 PF03175.13 CBK20855.2 - 2.2e-16 59.8 13.0 7.5e-14 51.4 8.9 2.3 2 0 0 2 2 2 2 DNA polymerase type B, organellar and viral zf-C3HC4_3 PF13920.6 CBK20856.2 - 4.3e-09 36.1 14.1 1.2e-08 34.6 10.5 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CBK20856.2 - 3.6e-07 29.9 12.0 3.6e-07 29.9 12.0 3.1 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CBK20856.2 - 8.6e-06 25.7 8.1 8.6e-06 25.7 8.1 3.2 2 2 1 3 3 3 1 RING-type zinc-finger zf-RING_2 PF13639.6 CBK20856.2 - 8.4e-05 22.8 19.5 0.00045 20.5 12.9 2.7 2 1 0 2 2 2 1 Ring finger domain zf-C3HC4_4 PF15227.6 CBK20856.2 - 0.00054 20.1 6.8 0.00054 20.1 6.8 2.7 2 1 0 2 2 2 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 CBK20856.2 - 0.00095 19.0 15.6 0.0057 16.5 11.1 3.0 2 1 1 3 3 3 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 CBK20856.2 - 0.001 19.0 18.2 0.0017 18.3 12.6 3.3 3 1 0 3 3 3 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 CBK20856.2 - 0.0016 18.2 19.1 0.0048 16.7 12.6 3.4 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) Pox_MCEL PF03291.16 CBK20856.2 - 0.05 12.7 0.0 0.061 12.4 0.0 1.1 1 0 0 1 1 1 0 mRNA capping enzyme zf-ANAPC11 PF12861.7 CBK20856.2 - 0.8 9.8 7.8 2.6 8.2 7.9 1.9 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-Di19 PF05605.12 CBK20856.2 - 0.91 9.9 10.4 0.37 11.1 1.6 3.3 3 0 0 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding zf-C3HC4_3 PF13920.6 CBK20858.2 - 5.7e-08 32.5 8.7 9.4e-08 31.8 8.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CBK20858.2 - 3.4e-06 26.8 11.0 8.5e-06 25.5 11.0 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 CBK20858.2 - 3.8e-06 26.6 8.5 6.6e-06 25.9 8.5 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 CBK20858.2 - 2.5e-05 24.0 10.4 2.5e-05 24.0 10.4 1.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CBK20858.2 - 0.00019 21.7 13.0 0.00019 21.7 11.7 1.8 2 0 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.6 CBK20858.2 - 0.0018 18.2 11.4 0.0018 18.2 9.8 1.9 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 CBK20858.2 - 0.0029 17.6 12.7 0.016 15.2 5.5 2.8 3 1 0 3 3 3 2 RING-type zinc-finger zf-rbx1 PF12678.7 CBK20858.2 - 0.017 15.4 8.2 0.042 14.2 8.2 1.6 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-RING_10 PF16685.5 CBK20858.2 - 0.033 14.3 5.8 0.057 13.6 5.8 1.4 1 0 0 1 1 1 0 zinc RING finger of MSL2 Zf_RING PF16744.5 CBK20858.2 - 1.2 9.3 8.5 0.24 11.5 3.0 2.3 1 1 1 2 2 2 0 KIAA1045 RING finger zf-RING_4 PF14570.6 CBK20858.2 - 1.6 8.6 18.9 0.13 12.1 12.3 2.5 2 2 1 3 3 3 0 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.6 CBK20858.2 - 5.5 7.2 15.8 6.9 6.9 11.9 3.2 3 1 1 4 4 4 0 zinc finger of C3HC4-type, RING Peptidase_C13 PF01650.18 CBK20860.2 - 2.4e-58 197.6 0.1 3.4e-58 197.2 0.1 1.1 1 0 0 1 1 1 1 Peptidase C13 family Peptidase_C14 PF00656.22 CBK20860.2 - 8.4e-05 22.6 0.1 0.0002 21.4 0.1 1.5 1 1 0 1 1 1 1 Caspase domain DUF3242 PF11586.8 CBK20860.2 - 0.00047 19.9 1.2 0.0013 18.5 0.7 2.1 1 1 1 2 2 2 1 Protein of unknown function (DUF3242) PHD PF00628.29 CBK20861.2 - 1e-05 25.3 8.0 1e-05 25.3 8.0 4.2 3 1 2 5 5 5 1 PHD-finger zf-C2H2 PF00096.26 CBK20861.2 - 0.0068 16.8 4.6 0.0068 16.8 4.6 5.1 5 0 0 5 5 5 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CBK20861.2 - 0.036 14.9 4.9 0.036 14.9 4.9 6.2 5 0 0 5 5 5 0 C2H2-type zinc finger zf-met PF12874.7 CBK20861.2 - 0.2 12.1 0.2 0.2 12.1 0.2 3.7 3 0 0 3 3 3 0 Zinc-finger of C2H2 type GAGA PF09237.11 CBK20861.2 - 4.6 7.1 8.3 0.2 11.5 1.8 2.1 2 0 0 2 2 2 0 GAGA factor Rad50_zn_hook PF04423.14 CBK20861.2 - 7.7 6.4 6.5 0.97 9.3 1.5 2.1 2 0 0 2 2 2 0 Rad50 zinc hook motif Mrr_cat PF04471.12 CBK20862.2 - 4.8e-09 36.2 0.2 2.3e-08 34.0 0.0 2.1 2 0 0 2 2 2 1 Restriction endonuclease YqhG PF11079.8 CBK20862.2 - 0.0059 15.6 0.3 0.0098 14.9 0.3 1.3 1 0 0 1 1 1 1 Bacterial protein YqhG of unknown function UPF0102 PF02021.17 CBK20862.2 - 0.024 14.8 1.0 0.08 13.2 0.0 2.3 2 1 0 2 2 2 0 Uncharacterised protein family UPF0102 Nup54 PF13874.6 CBK20862.2 - 0.2 11.7 6.0 0.59 10.2 2.1 2.2 2 0 0 2 2 2 0 Nucleoporin complex subunit 54 CitG PF01874.16 CBK20862.2 - 0.44 10.2 2.7 0.28 10.8 0.5 1.6 2 0 0 2 2 2 0 ATP:dephospho-CoA triphosphoribosyl transferase YpjP PF14005.6 CBK20862.2 - 1 9.4 6.7 0.29 11.2 3.5 1.7 2 0 0 2 2 2 0 YpjP-like protein adh_short PF00106.25 CBK20863.2 - 1.2e-52 178.3 0.0 1.4e-52 178.0 0.0 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CBK20863.2 - 2.3e-39 135.3 0.0 3.7e-39 134.7 0.0 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CBK20863.2 - 2.2e-13 50.5 0.0 3.1e-13 50.0 0.0 1.1 1 0 0 1 1 1 1 KR domain THF_DHG_CYH_C PF02882.19 CBK20863.2 - 0.006 15.9 0.1 0.043 13.1 0.0 2.1 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 3HCDH_N PF02737.18 CBK20863.2 - 0.1 12.5 0.0 0.14 12.0 0.0 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Ribosomal_L13 PF00572.18 CBK20864.2 - 1.7e-11 44.4 0.1 1.8e-09 37.9 0.1 2.3 1 1 0 1 1 1 1 Ribosomal protein L13 FAD_binding_2 PF00890.24 CBK20865.2 - 4e-121 405.0 3.1 5.3e-121 404.6 3.1 1.2 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.20 CBK20865.2 - 2.4e-44 150.4 1.8 3.5e-44 149.9 1.8 1.3 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term Thi4 PF01946.17 CBK20865.2 - 5.1e-06 25.9 0.1 0.0067 15.7 0.1 2.6 3 0 0 3 3 3 2 Thi4 family GIDA PF01134.22 CBK20865.2 - 5.4e-05 22.4 0.9 0.003 16.7 1.0 2.2 2 0 0 2 2 2 1 Glucose inhibited division protein A Pyr_redox_2 PF07992.14 CBK20865.2 - 0.0001 21.6 0.3 0.00029 20.2 0.2 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 CBK20865.2 - 0.00023 20.9 0.4 0.00039 20.1 0.4 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 CBK20865.2 - 0.00023 20.5 0.2 0.00041 19.7 0.2 1.4 1 0 0 1 1 1 1 FAD binding domain NAD_binding_7 PF13241.6 CBK20865.2 - 0.019 15.4 0.0 0.8 10.2 0.0 2.4 2 0 0 2 2 2 0 Putative NAD(P)-binding HI0933_like PF03486.14 CBK20865.2 - 0.029 13.1 1.6 0.051 12.3 0.3 2.0 3 0 0 3 3 3 0 HI0933-like protein NodZ PF05830.11 CBK20866.2 - 3.1e-05 23.0 0.0 8.1e-05 21.6 0.0 1.6 2 0 0 2 2 2 1 Nodulation protein Z (NodZ) XG_FTase PF03254.13 CBK20866.2 - 0.00023 20.0 0.7 0.011 14.4 0.0 2.4 3 0 0 3 3 3 2 Xyloglucan fucosyltransferase MORN PF02493.20 CBK20867.2 - 1.5e-10 40.3 44.7 0.038 13.9 0.3 10.7 12 0 0 12 12 12 6 MORN repeat LRR_8 PF13855.6 CBK20867.2 - 1.5e-05 24.7 0.0 0.28 11.0 0.0 3.1 3 0 0 3 3 3 2 Leucine rich repeat EndoU_bacteria PF14436.6 CBK20867.2 - 0.022 15.1 0.3 0.048 14.0 0.3 1.5 1 0 0 1 1 1 0 Bacterial EndoU nuclease RCC1 PF00415.18 CBK20868.2 - 3.2e-31 107.7 0.8 1.8e-09 38.0 0.0 5.2 5 0 0 5 5 5 3 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 CBK20868.2 - 3.9e-31 106.2 24.9 6.8e-07 28.9 0.0 8.4 8 0 0 8 8 8 7 Regulator of chromosome condensation (RCC1) repeat HECT PF00632.25 CBK20869.2 - 7.4e-65 219.4 0.0 8.9e-65 219.2 0.0 1.0 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) TPR_14 PF13428.6 CBK20870.2 - 0.0019 18.9 13.2 2.7 9.1 0.0 7.0 6 1 2 8 8 8 2 Tetratricopeptide repeat Suf PF05843.14 CBK20870.2 - 0.0048 16.9 5.2 1.9 8.4 0.1 3.6 3 1 0 3 3 3 2 Suppressor of forked protein (Suf) TPR_2 PF07719.17 CBK20870.2 - 0.069 13.3 3.2 2.4 8.5 0.1 4.8 5 0 0 5 5 5 0 Tetratricopeptide repeat Presenilin PF01080.17 CBK20870.2 - 1.8 7.3 4.3 2.6 6.7 4.3 1.1 1 0 0 1 1 1 0 Presenilin Mob1_phocein PF03637.17 CBK20871.2 - 7.2e-54 182.3 2.1 1e-53 181.9 2.1 1.2 1 0 0 1 1 1 1 Mob1/phocein family IZUMO PF15005.6 CBK20873.2 - 0.014 15.9 0.7 0.024 15.1 0.1 1.7 2 0 0 2 2 2 0 Izumo sperm-egg fusion, Ig domain-associated ApoA-II PF04711.13 CBK20873.2 - 0.048 13.8 0.0 0.16 12.1 0.0 1.8 1 0 0 1 1 1 0 Apolipoprotein A-II (ApoA-II) DUF4239 PF14023.6 CBK20873.2 - 0.65 9.7 2.0 4.7 6.9 0.1 2.1 1 1 0 2 2 2 0 Protein of unknown function (DUF4239) Trypan_PARP PF05887.11 CBK20873.2 - 0.7 9.9 54.2 0.091 12.7 7.2 3.0 2 1 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) DUF4200 PF13863.6 CBK20873.2 - 5.3 7.5 8.1 21 5.6 0.3 3.4 3 1 0 3 3 3 0 Domain of unknown function (DUF4200) TMEM117 PF15113.6 CBK20874.2 - 0.2 10.6 0.0 0.31 9.9 0.0 1.2 1 0 0 1 1 1 0 TMEM117 protein family Methyltransf_28 PF02636.17 CBK20875.2 - 2.7e-25 89.5 0.0 3.4e-25 89.2 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Lyase_1 PF00206.20 CBK20876.2 - 3.1e-89 299.5 0.0 1e-88 297.8 0.0 1.7 2 0 0 2 2 2 1 Lyase FumaraseC_C PF10415.9 CBK20876.2 - 1.3e-19 70.4 0.0 4e-19 68.8 0.0 1.9 1 0 0 1 1 1 1 Fumarase C C-terminus Thioredoxin PF00085.20 CBK20878.2 - 1.9e-05 24.6 0.0 2.4e-05 24.3 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_6 PF13848.6 CBK20878.2 - 0.1 12.5 0.0 0.12 12.3 0.0 1.1 1 0 0 1 1 1 0 Thioredoxin-like domain GTP_EFTU PF00009.27 CBK20879.2 - 9.9e-58 194.9 0.0 1.4e-57 194.4 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 CBK20879.2 - 2.5e-28 98.6 0.0 5e-28 97.6 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 CBK20879.2 - 8.3e-17 61.4 3.0 1.9e-16 60.2 3.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 CBK20879.2 - 4e-05 23.7 0.0 7.7e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase cobW PF02492.19 CBK20879.2 - 0.034 13.7 0.2 0.12 12.0 0.0 1.8 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain RsgA_GTPase PF03193.16 CBK20879.2 - 0.042 13.8 0.0 0.12 12.2 0.0 1.8 2 0 0 2 2 2 0 RsgA GTPase PduV-EutP PF10662.9 CBK20879.2 - 0.14 11.9 0.1 10 5.9 0.0 2.7 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation Oxidored_q6 PF01058.22 CBK20880.2 - 5.4e-23 81.3 0.0 8.2e-23 80.7 0.0 1.3 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit Secapin PF17521.2 CBK20880.2 - 0.038 13.8 0.6 0.14 12.0 0.0 2.2 2 0 0 2 2 2 0 Honey bee peptides Complex1_LYR_2 PF13233.6 CBK20881.2 - 4.5e-10 40.1 0.5 5.5e-10 39.9 0.5 1.2 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.15 CBK20881.2 - 0.03 14.4 0.4 0.073 13.1 0.4 1.7 1 0 0 1 1 1 0 Complex 1 protein (LYR family) SNF2_N PF00176.23 CBK20882.2 - 3.8e-41 141.0 0.0 5.1e-41 140.5 0.0 1.1 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 CBK20882.2 - 7.6e-14 52.0 0.0 1.7e-13 50.8 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 CBK20882.2 - 0.00083 19.4 0.0 0.0015 18.6 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 CBK20882.2 - 0.0024 17.7 0.0 0.0052 16.6 0.0 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase HDA2-3 PF11496.8 CBK20882.2 - 0.069 12.3 0.1 1.3 8.2 0.1 2.4 1 1 0 1 1 1 0 Class II histone deacetylase complex subunits 2 and 3 LRR_6 PF13516.6 CBK20883.2 - 6.4e-14 50.8 6.3 0.023 14.8 0.1 7.5 8 0 0 8 8 8 4 Leucine Rich repeat LRR_4 PF12799.7 CBK20883.2 - 1.7e-06 28.3 4.8 1.1 9.8 0.2 6.5 4 2 2 6 6 6 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 CBK20883.2 - 1.9e-05 24.5 0.4 24 6.0 0.0 6.6 6 0 0 6 6 6 2 Leucine Rich Repeat LRR_8 PF13855.6 CBK20883.2 - 7.3e-05 22.5 5.8 13 5.7 0.5 6.5 4 3 0 4 4 4 2 Leucine rich repeat CLIP PF12032.8 CBK20883.2 - 0.14 12.5 0.1 32 4.9 0.0 2.6 2 0 0 2 2 2 0 Regulatory CLIP domain of proteinases Aha1_N PF09229.11 CBK20884.2 - 8.4e-19 68.1 0.2 1.5e-18 67.3 0.2 1.3 1 0 0 1 1 1 1 Activator of Hsp90 ATPase, N-terminal DUF2744 PF10910.8 CBK20884.2 - 0.14 12.2 0.1 0.18 11.8 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2744) ComZ PF10815.8 CBK20884.2 - 0.15 12.1 0.2 8.8 6.4 0.0 2.2 2 0 0 2 2 2 0 ComZ Ribosomal_L14 PF00238.19 CBK20885.2 - 7e-35 119.8 0.0 7.6e-35 119.6 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e ICMT PF04140.14 CBK20886.2 - 3.3e-22 78.7 0.1 3.3e-22 78.7 0.1 1.8 2 1 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 CBK20886.2 - 3.1e-09 37.2 1.3 3.1e-09 37.2 1.3 2.3 2 0 0 2 2 2 1 Phospholipid methyltransferase DUF1295 PF06966.12 CBK20886.2 - 0.0035 16.9 0.5 0.0035 16.9 0.5 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF1295) PrgI PF12666.7 CBK20886.2 - 0.064 14.0 0.5 0.064 14.0 0.5 2.4 3 0 0 3 3 3 0 PrgI family protein Phage_holin_3_6 PF07332.11 CBK20886.2 - 0.11 12.5 1.2 0.24 11.5 0.2 1.8 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III Holin_SPP1 PF04688.13 CBK20886.2 - 2.4 8.4 5.8 0.49 10.6 2.1 1.8 2 0 0 2 2 2 0 SPP1 phage holin UL141 PF16758.5 CBK20887.2 - 0.12 12.1 0.0 0.21 11.3 0.0 1.4 1 0 0 1 1 1 0 Herpes-like virus membrane glycoprotein UL141 LRR_9 PF14580.6 CBK20889.2 - 8.5e-05 22.1 0.2 0.014 14.9 0.0 2.3 2 0 0 2 2 2 2 Leucine-rich repeat LRR_8 PF13855.6 CBK20889.2 - 0.06 13.1 2.8 0.18 11.6 0.2 2.9 2 2 2 4 4 4 0 Leucine rich repeat MORN PF02493.20 CBK20889.2 - 0.11 12.5 14.6 0.48 10.4 0.9 4.2 5 0 0 5 5 5 0 MORN repeat Nup96 PF12110.8 CBK20890.2 - 1.8e-22 79.8 0.0 3.4e-22 78.9 0.0 1.4 1 0 0 1 1 1 1 Nuclear protein 96 LRR_2 PF07723.13 CBK20890.2 - 2.1 9.1 4.9 2.2 9.1 0.0 3.4 4 0 0 4 4 4 0 Leucine Rich Repeat Rad60-SLD PF11976.8 CBK20891.2 - 0.0074 16.1 0.5 0.015 15.1 0.5 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF4813 PF16072.5 CBK20891.2 - 0.088 12.5 26.0 0.15 11.7 26.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4813) Nuc_sug_transp PF04142.15 CBK20892.2 - 1.3e-07 31.1 3.5 1.7e-07 30.7 3.5 1.1 1 0 0 1 1 1 1 Nucleotide-sugar transporter TraX PF05857.11 CBK20892.2 - 0.033 14.3 6.1 0.033 14.3 5.5 1.4 1 1 0 1 1 1 0 TraX protein EamA PF00892.20 CBK20892.2 - 1.3 9.2 11.7 2.7 8.2 7.2 3.0 1 1 1 2 2 2 0 EamA-like transporter family tRNA_anti-codon PF01336.25 CBK20893.2 - 1.3e-07 31.5 0.1 2.5e-07 30.6 0.1 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain RMI2 PF16100.5 CBK20893.2 - 0.00084 19.2 0.0 0.0013 18.5 0.0 1.3 1 0 0 1 1 1 1 RecQ-mediated genome instability protein 2 CDC24_OB3 PF17244.2 CBK20893.2 - 0.0089 15.8 0.2 0.011 15.5 0.2 1.3 1 1 0 1 1 1 1 Cell division control protein 24, OB domain 3 RRM_1 PF00076.22 CBK20895.2 - 5.7e-14 51.7 0.0 1.3e-13 50.6 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ubiquitin_2 PF14560.6 CBK20896.2 - 6.2e-22 77.9 0.0 1.1e-21 77.1 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-like domain CAP_GLY PF01302.25 CBK20896.2 - 1.1e-21 76.6 2.2 1.9e-21 75.8 2.2 1.4 1 0 0 1 1 1 1 CAP-Gly domain ubiquitin PF00240.23 CBK20896.2 - 3.9e-06 26.5 0.0 2.4e-05 24.0 0.0 2.2 1 1 0 1 1 1 1 Ubiquitin family FGAR-AT_linker PF18072.1 CBK20896.2 - 0.13 12.8 0.0 10 6.7 0.0 2.6 2 0 0 2 2 2 0 Formylglycinamide ribonucleotide amidotransferase linker domain DUF563 PF04577.14 CBK20897.2 - 2e-20 73.9 0.0 3.2e-20 73.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF563) Mpv17_PMP22 PF04117.12 CBK20897.2 - 0.00099 19.3 1.7 0.0057 16.9 1.6 2.2 1 1 1 2 2 2 1 Mpv17 / PMP22 family Ribosomal_L1 PF00687.21 CBK20898.2 - 5.5e-44 150.3 5.8 6.9e-44 150.0 5.8 1.0 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family zf-TRAF_2 PF15965.5 CBK20898.2 - 0.081 13.4 1.5 0.44 11.0 0.5 2.2 2 0 0 2 2 2 0 TRAF-like zinc-finger PX PF00787.24 CBK20899.2 - 1.2e-22 80.0 0.2 2.6e-22 78.9 0.2 1.6 1 0 0 1 1 1 1 PX domain Vps5 PF09325.10 CBK20899.2 - 1.3e-20 73.9 2.9 3.1e-20 72.7 2.9 1.6 1 0 0 1 1 1 1 Vps5 C terminal like Syntaxin_2 PF14523.6 CBK20899.2 - 0.061 13.7 3.9 0.84 10.0 0.2 3.2 1 1 1 2 2 2 0 Syntaxin-like protein Tape_meas_lam_C PF09718.10 CBK20899.2 - 0.085 13.0 0.8 28 4.9 0.1 3.7 3 0 0 3 3 3 0 Lambda phage tail tape-measure protein (Tape_meas_lam_C) DUF948 PF06103.11 CBK20899.2 - 0.12 12.6 1.6 8.9 6.7 0.0 2.8 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF948) BLOC1_2 PF10046.9 CBK20899.2 - 0.31 11.3 5.1 0.67 10.3 0.7 3.3 2 2 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 FAP PF07174.11 CBK20899.2 - 0.4 10.1 17.5 0.68 9.3 17.5 1.3 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) Clat_adaptor_s PF01217.20 CBK20900.2 - 9.2e-34 116.4 5.4 1.1e-33 116.2 5.4 1.1 1 0 0 1 1 1 1 Clathrin adaptor complex small chain NADPH_Ox PF08414.10 CBK20900.2 - 0.0058 16.9 0.0 0.051 13.9 0.0 2.1 2 0 0 2 2 2 1 Respiratory burst NADPH oxidase Mon1 PF03164.14 CBK20900.2 - 0.088 11.9 0.4 0.12 11.4 0.4 1.2 1 0 0 1 1 1 0 Trafficking protein Mon1 FYVE PF01363.21 CBK20902.2 - 2.7e-18 65.8 9.5 2.7e-18 65.8 9.5 1.8 2 0 0 2 2 2 1 FYVE zinc finger F-box PF00646.33 CBK20902.2 - 0.014 15.2 0.3 0.047 13.6 0.3 2.0 1 0 0 1 1 1 0 F-box domain FYVE_2 PF02318.16 CBK20902.2 - 0.96 9.7 6.8 3.2 8.0 6.8 1.9 1 0 0 1 1 1 0 FYVE-type zinc finger HECT PF00632.25 CBK20903.2 - 3.9e-61 207.2 0.0 8.4e-61 206.1 0.0 1.5 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Ribosomal_L7Ae PF01248.26 CBK20904.2 - 1.1e-21 76.3 0.3 1.5e-21 75.9 0.3 1.2 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Mpv17_PMP22 PF04117.12 CBK20905.2 - 7.1e-17 61.4 5.7 1.5e-16 60.4 5.7 1.5 1 0 0 1 1 1 1 Mpv17 / PMP22 family WD40 PF00400.32 CBK20906.2 - 1.6e-22 79.4 6.4 1.9e-07 31.7 0.2 5.8 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBK20906.2 - 0.00051 20.3 0.0 0.99 9.7 0.0 4.0 4 0 0 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain DUF5122 PF17164.4 CBK20906.2 - 0.91 9.9 5.5 0.56 10.5 0.3 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF5122) beta-propeller FYVE PF01363.21 CBK20907.2 - 1.5e-14 53.9 5.4 1.5e-14 53.9 5.4 1.9 2 0 0 2 2 2 1 FYVE zinc finger DUF3376 PF11856.8 CBK20907.2 - 0.0038 16.3 0.1 0.0052 15.8 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3376) Tab2_like PF06485.11 CBK20907.2 - 0.15 11.5 0.0 0.2 11.2 0.0 1.3 1 0 0 1 1 1 0 RNA-binding protein Tab2/Atab2 zf-CRD PF17979.1 CBK20907.2 - 0.57 10.3 5.3 0.64 10.1 3.3 2.0 2 0 0 2 2 2 0 Cysteine rich domain with multizinc binding regions Pkinase PF00069.25 CBK20909.2 - 4.8e-27 95.0 0.1 7.2e-27 94.4 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBK20909.2 - 2.2e-23 82.8 0.0 3.2e-23 82.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 CBK20909.2 - 0.0002 20.7 0.0 0.00038 19.9 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CBK20909.2 - 0.028 14.4 0.0 0.15 11.9 0.0 1.9 1 1 1 2 2 2 0 Phosphotransferase enzyme family FTA2 PF13095.6 CBK20909.2 - 0.04 13.5 0.1 1.9 8.0 0.0 2.2 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 UEV PF05743.13 CBK20909.2 - 0.057 13.3 0.0 0.1 12.5 0.0 1.4 1 0 0 1 1 1 0 UEV domain Pkinase_fungal PF17667.1 CBK20909.2 - 0.1 11.4 0.0 0.16 10.7 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Snf7 PF03357.21 CBK20911.2 - 1.4e-09 37.8 22.5 1.4e-09 37.8 22.5 1.9 1 1 1 2 2 2 1 Snf7 Erf4 PF10256.9 CBK20911.2 - 0.0018 18.4 0.7 0.0032 17.5 0.6 1.4 1 1 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family TPR_MLP1_2 PF07926.12 CBK20911.2 - 0.0047 17.0 14.3 0.085 12.9 9.4 2.7 2 1 0 2 2 2 1 TPR/MLP1/MLP2-like protein Spectrin PF00435.21 CBK20911.2 - 0.012 16.1 13.0 0.62 10.6 5.9 2.6 1 1 1 2 2 2 0 Spectrin repeat DUF948 PF06103.11 CBK20911.2 - 0.02 15.1 9.6 8.1 6.8 9.6 2.6 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) Noelin-1 PF12308.8 CBK20911.2 - 0.028 14.4 13.7 0.84 9.6 1.2 3.3 1 1 2 3 3 3 0 Neurogenesis glycoprotein DUF3813 PF12758.7 CBK20911.2 - 0.031 14.6 4.8 0.098 13.0 0.0 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF3813) SPOUT_MTase_2 PF14419.6 CBK20911.2 - 0.083 12.2 0.2 0.13 11.6 0.2 1.3 1 0 0 1 1 1 0 AF2226-like SPOUT RNA Methylase fused to THUMP LIAS_N PF16881.5 CBK20911.2 - 0.2 12.1 0.1 0.2 12.1 0.1 2.2 2 1 0 2 2 2 0 N-terminal domain of lipoyl synthase of Radical_SAM family ANAPC4 PF12896.7 CBK20911.2 - 0.42 10.1 5.0 2.7 7.4 0.6 2.3 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 4 FAM76 PF16046.5 CBK20911.2 - 0.62 9.4 14.1 0.92 8.8 14.1 1.2 1 0 0 1 1 1 0 FAM76 protein DUF1706 PF08020.11 CBK20911.2 - 1 9.2 6.5 0.58 10.1 0.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1706) TPR_20 PF14561.6 CBK20911.2 - 1.3 9.4 7.6 0.15 12.4 1.6 2.5 2 2 0 2 2 2 0 Tetratricopeptide repeat Snapin_Pallidin PF14712.6 CBK20911.2 - 3 8.3 16.3 43 4.6 7.5 3.9 1 1 2 3 3 3 0 Snapin/Pallidin T3SSipB PF16535.5 CBK20911.2 - 4.8 7.7 18.0 9.8 6.6 1.6 2.2 1 1 1 2 2 2 0 Type III cell invasion protein SipB DUF883 PF05957.13 CBK20911.2 - 6.3 7.5 11.4 0.58 10.8 0.4 2.8 3 1 0 3 3 2 0 Bacterial protein of unknown function (DUF883) YtxH PF12732.7 CBK20911.2 - 6.4 7.4 12.2 0.48 11.0 3.1 2.7 1 1 1 2 2 2 0 YtxH-like protein Baculo_p24 PF05073.12 CBK20911.2 - 9.1 6.0 10.6 81 2.9 10.6 2.1 1 1 0 1 1 1 0 Baculovirus P24 capsid protein SYF2 PF08231.12 CBK20911.2 - 9.7 6.6 14.2 2.4e+02 2.1 13.9 2.4 1 1 0 1 1 1 0 SYF2 splicing factor PI3_PI4_kinase PF00454.27 CBK20912.2 - 9.6e-27 94.4 0.7 8.6e-20 71.6 0.3 2.0 1 1 1 2 2 2 2 Phosphatidylinositol 3- and 4-kinase RCC1 PF00415.18 CBK20913.2 - 4.2e-22 78.5 8.3 4.4e-11 43.2 1.0 3.4 3 1 0 3 3 3 3 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 CBK20913.2 - 1.7e-14 53.2 16.2 2.7e-07 30.2 5.3 2.3 2 0 0 2 2 2 2 Regulator of chromosome condensation (RCC1) repeat TssR PF17643.1 CBK20914.2 - 0.084 10.8 0.0 0.093 10.7 0.0 1.1 1 0 0 1 1 1 0 Type VI secretion system, TssR TFCD_C PF12612.8 CBK20915.2 - 5.5e-07 29.6 0.2 2.4e-06 27.5 0.1 2.3 2 0 0 2 2 2 1 Tubulin folding cofactor D C terminal Cnd1 PF12717.7 CBK20915.2 - 0.0061 16.6 0.1 0.018 15.1 0.1 1.9 1 0 0 1 1 1 1 non-SMC mitotic condensation complex subunit 1 TAF6_C PF07571.13 CBK20915.2 - 0.032 14.6 0.4 26 5.2 0.0 3.8 3 0 0 3 3 3 0 TAF6 C-terminal HEAT repeat domain HEAT PF02985.22 CBK20915.2 - 0.16 12.3 0.2 1.1e+02 3.4 0.0 4.8 5 0 0 5 5 5 0 HEAT repeat HEAT_2 PF13646.6 CBK20915.2 - 0.21 12.0 0.6 23 5.5 0.1 4.0 4 1 0 4 4 4 0 HEAT repeats RRM_1 PF00076.22 CBK20916.2 - 7.3e-08 32.1 0.0 1.1e-07 31.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DDE_3 PF13358.6 CBK20916.2 - 0.08 12.7 0.1 0.13 12.1 0.1 1.2 1 0 0 1 1 1 0 DDE superfamily endonuclease Orn_DAP_Arg_deC PF00278.22 CBK20917.2 - 2.8e-15 56.3 0.0 5.3e-15 55.4 0.0 1.3 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain Orn_Arg_deC_N PF02784.16 CBK20917.2 - 0.036 13.4 0.0 0.1 11.9 0.0 1.7 1 1 0 1 1 1 0 Pyridoxal-dependent decarboxylase, pyridoxal binding domain ETF_alpha PF00766.19 CBK20917.2 - 0.13 12.3 0.0 0.24 11.4 0.0 1.4 1 0 0 1 1 1 0 Electron transfer flavoprotein FAD-binding domain Mob1_phocein PF03637.17 CBK20918.2 - 8.6e-56 188.6 0.1 8.6e-56 188.6 0.1 2.0 2 0 0 2 2 2 1 Mob1/phocein family PRY PF13765.6 CBK20918.2 - 7 6.4 6.4 40 3.9 0.5 3.5 3 0 0 3 3 3 0 SPRY-associated domain WBS_methylT PF12589.8 CBK20919.2 - 8.4e-16 58.5 3.9 1.3e-15 57.9 3.9 1.3 1 0 0 1 1 1 1 Methyltransferase involved in Williams-Beuren syndrome Methyltransf_11 PF08241.12 CBK20919.2 - 2.9e-10 40.7 0.0 5.4e-10 39.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CBK20919.2 - 9.8e-10 39.0 0.0 2e-09 38.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 CBK20919.2 - 0.00045 20.1 0.0 0.00067 19.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CBK20919.2 - 0.00073 20.2 0.2 0.0022 18.7 0.0 2.0 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 CBK20919.2 - 0.041 13.7 0.0 0.062 13.1 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain GnsAB_toxin PF08178.11 CBK20919.2 - 0.046 13.7 0.0 0.095 12.6 0.0 1.4 1 0 0 1 1 1 0 GnsA/GnsB toxin of bacterial toxin-antitoxin system SMN PF06003.12 CBK20919.2 - 9.6 5.4 9.2 13 5.0 9.2 1.2 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) DUF1279 PF06916.13 CBK20920.2 - 5.9e-05 23.5 0.2 9.9e-05 22.8 0.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1279) GRP PF07172.11 CBK20920.2 - 8.7 7.1 20.2 2.8 8.7 16.6 1.9 2 0 0 2 2 2 0 Glycine rich protein family IBN_N PF03810.19 CBK20923.2 - 1.5e-14 53.6 0.0 4.4e-14 52.1 0.0 1.9 1 0 0 1 1 1 1 Importin-beta N-terminal domain CHD5 PF04420.14 CBK20923.2 - 0.021 14.7 0.1 0.075 12.9 0.1 2.0 1 0 0 1 1 1 0 CHD5-like protein Ribosomal_L22e PF01776.17 CBK20924.2 - 1.3e-18 67.3 0.1 1.5e-18 67.2 0.1 1.0 1 0 0 1 1 1 1 Ribosomal L22e protein family RNA_pol_Rpc4 PF05132.14 CBK20925.2 - 0.52 10.7 5.6 13 6.2 1.8 2.3 2 0 0 2 2 2 0 RNA polymerase III RPC4 C2 PF00168.30 CBK20926.2 - 4.2e-10 39.8 0.0 7.2e-10 39.1 0.0 1.4 1 0 0 1 1 1 1 C2 domain DUF4436 PF14494.6 CBK20927.2 - 0.12 11.7 0.0 0.14 11.4 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4436) Peptidase_S24 PF00717.23 CBK20928.2 - 2.5e-08 33.8 0.1 3.3e-08 33.4 0.1 1.2 1 0 0 1 1 1 1 Peptidase S24-like WD40 PF00400.32 CBK20929.2 - 3.5e-19 68.8 16.8 1e-05 26.2 0.1 6.9 6 2 1 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBK20929.2 - 8.5e-06 26.0 2.9 0.041 14.2 0.0 4.5 4 1 1 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Ribosomal_L2_C PF03947.18 CBK20930.2 - 1.4e-45 154.6 1.6 2.1e-45 154.0 1.6 1.2 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 CBK20930.2 - 1.2e-14 54.0 0.1 3.4e-14 52.6 0.0 1.9 2 0 0 2 2 2 1 Ribosomal Proteins L2, RNA binding domain DHHC PF01529.20 CBK20931.2 - 2.2e-19 69.9 10.4 3.7e-19 69.2 10.4 1.4 1 0 0 1 1 1 1 DHHC palmitoyltransferase Cys_rich_CPCC PF14206.6 CBK20931.2 - 0.24 11.2 6.9 0.27 11.1 5.7 1.7 2 0 0 2 2 2 0 Cysteine-rich CPCC zf-HIT PF04438.16 CBK20931.2 - 0.48 10.3 7.5 1.4 8.8 7.5 1.8 1 0 0 1 1 1 0 HIT zinc finger ubiquitin PF00240.23 CBK20932.2 - 2.5e-34 116.8 0.5 3.6e-34 116.3 0.5 1.3 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_S30 PF04758.14 CBK20932.2 - 7.5e-27 93.3 7.4 1.3e-26 92.5 7.4 1.3 1 0 0 1 1 1 1 Ribosomal protein S30 Rad60-SLD PF11976.8 CBK20932.2 - 7.1e-16 57.8 0.6 1e-15 57.3 0.6 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 CBK20932.2 - 2.4e-05 24.7 0.1 9.1e-05 22.8 0.1 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain DUF2407 PF10302.9 CBK20932.2 - 0.00013 22.5 0.4 0.00023 21.7 0.4 1.4 1 1 0 1 1 1 1 DUF2407 ubiquitin-like domain Sde2_N_Ubi PF13019.6 CBK20932.2 - 0.001 18.9 0.3 0.0018 18.2 0.3 1.4 1 1 0 1 1 1 1 Silencing defective 2 N-terminal ubiquitin domain TBK1_ULD PF18396.1 CBK20932.2 - 0.0063 16.4 0.0 0.0093 15.9 0.0 1.3 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain Ubiquitin_5 PF18037.1 CBK20932.2 - 0.0078 16.6 0.0 0.015 15.6 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 CBK20932.2 - 0.0094 16.0 0.3 0.025 14.7 0.3 1.9 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_4 PF18036.1 CBK20932.2 - 0.26 11.4 5.2 4.9 7.3 0.2 2.5 3 0 0 3 3 3 0 Ubiquitin-like domain DUF4988 PF16378.5 CBK20933.2 - 0.16 11.6 0.0 1 9.0 0.0 2.2 3 0 0 3 3 3 0 Domain of unknown function AAA_5 PF07728.14 CBK20935.2 - 2.9e-56 189.3 0.0 3.2e-13 49.9 0.0 7.7 8 0 0 8 8 7 5 AAA domain (dynein-related subfamily) AAA_7 PF12775.7 CBK20935.2 - 4.6e-16 58.9 0.4 0.0039 16.7 0.0 6.0 6 0 0 6 6 6 4 P-loop containing dynein motor region AAA_3 PF07726.11 CBK20935.2 - 5.5e-12 45.7 0.0 1.9e-07 31.0 0.0 3.4 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 CBK20935.2 - 2.6e-11 43.7 0.0 0.0039 17.2 0.0 5.7 4 0 0 4 4 4 2 AAA domain Dynein_heavy PF03028.15 CBK20935.2 - 8.1e-10 38.8 0.0 1.1e-05 25.4 0.0 4.3 3 0 0 3 3 3 1 Dynein heavy chain region D6 P-loop domain AAA_22 PF13401.6 CBK20935.2 - 1.3e-09 38.4 2.4 0.36 11.1 0.0 7.2 7 2 0 7 7 6 2 AAA domain Sigma54_activat PF00158.26 CBK20935.2 - 8.3e-08 32.1 0.0 0.0047 16.6 0.0 4.6 5 0 0 5 5 5 2 Sigma-54 interaction domain AAA PF00004.29 CBK20935.2 - 1.7e-06 28.5 0.0 0.052 14.0 0.0 4.8 4 0 0 4 4 4 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 CBK20935.2 - 3.2e-06 27.6 0.0 3.3 8.1 0.0 5.5 5 0 0 5 5 5 1 AAA ATPase domain AAA_33 PF13671.6 CBK20935.2 - 0.00029 21.0 0.0 2.1 8.5 0.0 4.2 5 0 0 5 5 4 1 AAA domain AAA_24 PF13479.6 CBK20935.2 - 0.016 14.9 0.0 19 4.9 0.0 4.1 3 0 0 3 3 3 0 AAA domain RNA_helicase PF00910.22 CBK20935.2 - 0.035 14.5 4.0 4.4 7.7 0.0 5.0 4 0 0 4 4 4 0 RNA helicase AAA_18 PF13238.6 CBK20935.2 - 0.04 14.5 2.6 44 4.6 0.0 5.4 5 0 0 5 5 4 0 AAA domain Viral_helicase1 PF01443.18 CBK20935.2 - 0.066 13.0 0.0 2.2 8.0 0.0 3.1 3 0 0 3 3 3 0 Viral (Superfamily 1) RNA helicase AAA_30 PF13604.6 CBK20935.2 - 0.077 12.7 0.0 15 5.3 0.0 4.1 5 0 0 5 5 4 0 AAA domain DUF4600 PF15372.6 CBK20935.2 - 0.14 12.6 11.4 0.053 14.0 5.9 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4600) DUF3755 PF12579.8 CBK20935.2 - 0.14 11.8 2.1 0.31 10.7 0.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3755) ABC_tran PF00005.27 CBK20935.2 - 0.15 12.5 0.0 41 4.7 0.0 3.2 2 0 0 2 2 2 0 ABC transporter ERp29 PF07749.12 CBK20935.2 - 0.35 11.8 4.1 3.3 8.7 0.0 3.4 2 0 0 2 2 2 0 Endoplasmic reticulum protein ERp29, C-terminal domain FtsX PF02687.21 CBK20936.2 - 1.9e-05 25.0 8.4 1.9e-05 25.0 8.4 5.0 4 1 0 4 4 4 1 FtsX-like permease family YwcE PF17368.2 CBK20936.2 - 4.6 8.0 11.0 0.11 13.1 1.3 2.8 2 0 0 2 2 2 0 Spore morphogenesis and germination YwcE IP_trans PF02121.18 CBK20937.2 - 7.3e-08 32.3 1.4 9.4e-08 31.9 1.4 1.2 1 0 0 1 1 1 1 Phosphatidylinositol transfer protein IP_trans PF02121.18 CBK20938.2 - 3.3e-56 190.6 0.0 4.1e-56 190.3 0.0 1.0 1 0 0 1 1 1 1 Phosphatidylinositol transfer protein UEV PF05743.13 CBK20939.2 - 9.5e-08 31.9 0.3 1.9e-07 30.9 0.1 1.7 2 0 0 2 2 2 1 UEV domain EzrA PF06160.12 CBK20939.2 - 4.1e-05 22.0 0.2 5.6e-05 21.5 0.2 1.3 1 0 0 1 1 1 1 Septation ring formation regulator, EzrA bZIP_1 PF00170.21 CBK20939.2 - 0.01 15.9 0.3 0.054 13.6 0.2 2.2 2 0 0 2 2 2 0 bZIP transcription factor APG6_N PF17675.1 CBK20939.2 - 0.016 15.7 3.2 0.016 15.7 3.2 1.7 2 0 0 2 2 2 0 Apg6 coiled-coil region V_ATPase_I PF01496.19 CBK20939.2 - 0.12 10.3 1.3 0.15 10.0 1.3 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4215 PF13948.6 CBK20939.2 - 0.19 12.2 8.1 0.22 12.0 0.2 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4215) ZapB PF06005.12 CBK20939.2 - 0.24 11.9 3.2 0.5 10.9 2.4 2.0 1 1 0 1 1 1 0 Cell division protein ZapB BST2 PF16716.5 CBK20939.2 - 0.39 11.3 5.6 0.38 11.3 3.9 1.9 2 0 0 2 2 2 0 Bone marrow stromal antigen 2 KxDL PF10241.9 CBK20939.2 - 3.3 8.1 7.5 20 5.5 0.1 3.2 2 1 1 3 3 3 0 Uncharacterized conserved protein WXG100 PF06013.12 CBK20939.2 - 9.1 6.6 11.3 2.1 8.7 3.0 2.9 2 1 1 3 3 3 0 Proteins of 100 residues with WXG Glyco_transf_49 PF13896.6 CBK20940.2 - 0.00013 21.4 0.9 0.00014 21.4 0.8 1.2 1 1 0 1 1 1 1 Glycosyl-transferase for dystroglycan HECT PF00632.25 CBK20941.2 - 1.1e-26 94.0 0.0 1.4e-26 93.7 0.0 1.0 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Uteroglobin PF01099.17 CBK20941.2 - 0.1 12.9 0.0 0.19 12.1 0.0 1.4 1 0 0 1 1 1 0 Uteroglobin family Lectin_leg-like PF03388.13 CBK20942.2 - 1.4e-32 112.9 0.5 2.1e-32 112.3 0.5 1.2 1 0 0 1 1 1 1 Legume-like lectin family Lectin_legB PF00139.19 CBK20942.2 - 5.3e-07 29.4 0.3 1.3e-06 28.2 0.1 1.7 2 0 0 2 2 2 1 Legume lectin domain Bact_lectin PF18483.1 CBK20942.2 - 8.8e-05 22.6 2.3 0.00014 21.9 2.3 1.3 1 0 0 1 1 1 1 Bacterial lectin GvpL_GvpF PF06386.11 CBK20942.2 - 0.059 13.3 1.6 0.096 12.6 1.6 1.2 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF Prominin PF05478.11 CBK20942.2 - 0.14 10.1 1.2 0.2 9.5 1.2 1.2 1 0 0 1 1 1 0 Prominin TMPIT PF07851.13 CBK20942.2 - 0.16 11.1 3.7 0.21 10.8 3.7 1.1 1 0 0 1 1 1 0 TMPIT-like protein Collectrin PF16959.5 CBK20942.2 - 0.18 11.5 1.4 0.38 10.5 1.4 1.6 1 1 0 1 1 1 0 Renal amino acid transporter DUF1664 PF07889.12 CBK20942.2 - 0.19 11.8 4.6 0.39 10.8 4.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Spc7 PF08317.11 CBK20942.2 - 0.26 10.1 7.7 0.36 9.7 7.7 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF1351 PF07083.11 CBK20942.2 - 0.37 10.5 5.9 0.66 9.7 5.9 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1351) DUF3223 PF11523.8 CBK20942.2 - 1.7 9.5 4.8 13 6.7 0.4 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3223) Muted PF14942.6 CBK20942.2 - 2 8.7 9.8 3.7 7.9 9.8 1.4 1 0 0 1 1 1 0 Organelle biogenesis, Muted-like protein DUF1451 PF07295.11 CBK20942.2 - 6 6.9 6.7 4.9 7.2 1.9 2.2 1 1 1 2 2 2 0 Zinc-ribbon containing domain CRAL_TRIO PF00650.20 CBK20943.2 - 1e-24 87.1 0.3 1.9e-24 86.2 0.3 1.4 1 0 0 1 1 1 1 CRAL/TRIO domain EMP24_GP25L PF01105.24 CBK20943.2 - 0.051 13.5 0.0 0.089 12.7 0.0 1.3 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD Prp18 PF02840.15 CBK20944.2 - 7.3e-43 146.0 0.0 7.3e-43 146.0 0.0 1.4 2 0 0 2 2 2 1 Prp18 domain Xpo1 PF08389.12 CBK20945.2 - 0.013 15.6 1.5 0.019 15.0 0.5 1.8 2 0 0 2 2 2 0 Exportin 1-like protein Bromodomain PF00439.25 CBK20947.2 - 1.9e-10 40.6 0.0 4.2e-10 39.6 0.0 1.6 1 0 0 1 1 1 1 Bromodomain DDT PF02791.17 CBK20947.2 - 0.07 13.5 0.0 0.21 11.9 0.0 1.8 2 0 0 2 2 2 0 DDT domain Mit_proteolip PF08039.11 CBK20949.2 - 0.057 13.9 0.0 0.086 13.3 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial proteolipid Mito_fiss_reg PF05308.11 CBK20950.2 - 0.12 12.5 0.4 0.14 12.2 0.4 1.1 1 0 0 1 1 1 0 Mitochondrial fission regulator PRIMA1 PF16101.5 CBK20950.2 - 0.61 10.1 7.1 0.9 9.6 7.1 1.4 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 CAP_N PF01213.19 CBK20950.2 - 2 7.8 6.3 2.6 7.5 6.3 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal DNA_pol_B_2 PF03175.13 CBK20951.2 - 2.2e-17 63.1 12.4 8e-15 54.6 8.3 2.4 2 0 0 2 2 2 2 DNA polymerase type B, organellar and viral DNA_pol_B_2 PF03175.13 CBK20952.2 - 5.5e-14 51.9 7.5 5.5e-14 51.9 7.5 1.7 2 0 0 2 2 2 1 DNA polymerase type B, organellar and viral POR_N PF01855.19 CBK20953.2 - 1.1e-58 198.7 0.1 1.9e-58 198.0 0.1 1.3 1 0 0 1 1 1 1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg POR PF01558.18 CBK20953.2 - 2.2e-28 99.5 0.5 4.8e-28 98.4 0.5 1.6 1 0 0 1 1 1 1 Pyruvate ferredoxin/flavodoxin oxidoreductase PFOR_II PF17147.4 CBK20953.2 - 6.3e-15 55.3 0.1 2.1e-14 53.6 0.1 2.0 1 0 0 1 1 1 1 Pyruvate:ferredoxin oxidoreductase core domain II Fer4_16 PF13484.6 CBK20953.2 - 1.2e-10 42.1 15.2 3.7e-08 34.2 8.7 2.8 1 1 1 2 2 2 2 4Fe-4S double cluster binding domain Fer4_7 PF12838.7 CBK20953.2 - 1.6e-09 38.2 6.7 5.9e-09 36.4 6.7 2.1 1 0 0 1 1 1 1 4Fe-4S dicluster domain EKR PF10371.9 CBK20953.2 - 6e-09 35.6 0.0 1.9e-08 33.9 0.0 1.9 1 0 0 1 1 1 1 Domain of unknown function TPP_enzyme_C PF02775.21 CBK20953.2 - 2e-08 34.1 0.2 5.8e-08 32.7 0.2 1.8 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Fer4_9 PF13187.6 CBK20953.2 - 3.5e-08 33.5 6.0 0.0022 18.1 1.0 2.7 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4 PF00037.27 CBK20953.2 - 5.2e-08 32.4 18.7 1.8e-05 24.3 1.3 3.2 3 0 0 3 3 3 2 4Fe-4S binding domain Fer4_21 PF14697.6 CBK20953.2 - 9.9e-08 32.0 7.6 0.0017 18.5 1.0 2.9 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_10 PF13237.6 CBK20953.2 - 1.8e-07 31.1 7.8 0.0032 17.5 1.0 2.8 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_6 PF12837.7 CBK20953.2 - 2.5e-06 27.3 19.3 2.3e-05 24.3 2.7 3.1 3 0 0 3 3 3 2 4Fe-4S binding domain Fer4_8 PF13183.6 CBK20953.2 - 3e-05 24.4 6.4 0.00015 22.1 6.5 2.2 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_18 PF13746.6 CBK20953.2 - 0.00086 19.5 3.6 0.42 10.8 0.4 2.8 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_2 PF12797.7 CBK20953.2 - 0.00097 19.1 22.7 0.02 15.0 4.3 3.2 3 0 0 3 3 3 2 4Fe-4S binding domain Fer4_17 PF13534.6 CBK20953.2 - 0.0011 19.4 12.2 0.011 16.2 11.1 2.8 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_13 PF13370.6 CBK20953.2 - 0.0012 19.3 8.5 0.11 13.0 1.3 3.4 3 0 0 3 3 3 2 4Fe-4S single cluster domain of Ferredoxin I Fer4_4 PF12800.7 CBK20953.2 - 0.0054 17.2 17.8 0.0079 16.6 1.4 3.1 3 0 0 3 3 2 2 4Fe-4S binding domain Glycos_transf_N PF04413.16 CBK20953.2 - 0.09 12.4 0.0 0.65 9.6 0.0 2.3 2 0 0 2 2 2 0 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) Transketolase_C PF02780.20 CBK20953.2 - 0.095 12.6 0.0 0.32 10.9 0.0 1.9 1 0 0 1 1 1 0 Transketolase, C-terminal domain BrkDBD PF09607.10 CBK20953.2 - 0.14 12.0 0.3 0.97 9.3 0.1 2.4 2 0 0 2 2 2 0 Brinker DNA-binding domain Fer4_15 PF13459.6 CBK20953.2 - 1.1 10.0 9.5 8.6 7.2 1.4 3.0 2 0 0 2 2 2 0 4Fe-4S single cluster domain Fer4_3 PF12798.7 CBK20953.2 - 2.6 9.2 19.4 7.9 7.7 5.7 2.8 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_22 PF17179.4 CBK20953.2 - 9.2 7.2 12.5 13 6.7 0.2 3.5 2 1 2 4 4 4 0 4Fe-4S dicluster domain RabGAP-TBC PF00566.18 CBK20954.2 - 8.2e-10 38.7 0.8 8.2e-10 38.7 0.8 2.8 3 1 0 3 3 3 1 Rab-GTPase-TBC domain Osmo_CC PF08946.10 CBK20954.2 - 0.036 14.3 1.9 6 7.2 0.5 3.4 3 0 0 3 3 3 0 Osmosensory transporter coiled coil DUF1664 PF07889.12 CBK20954.2 - 0.058 13.4 5.6 0.34 10.9 0.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Baculo_PEP_C PF04513.12 CBK20954.2 - 1.1 9.4 9.4 0.55 10.3 3.3 2.7 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus BLOC1_2 PF10046.9 CBK20954.2 - 1.5 9.2 8.7 0.48 10.7 1.8 2.7 2 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 RSS_P20 PF11757.8 CBK20954.2 - 4.1 7.9 8.6 0.88 10.1 0.9 3.2 2 1 1 3 3 3 0 Suppressor of RNA silencing P21-like N-terminal domain Lectin_leg-like PF03388.13 CBK20955.2 - 1.6e-37 129.0 0.9 2.2e-37 128.6 0.9 1.1 1 0 0 1 1 1 1 Legume-like lectin family Bact_lectin PF18483.1 CBK20955.2 - 1.5e-08 34.9 0.9 2.7e-08 34.1 0.9 1.4 1 0 0 1 1 1 1 Bacterial lectin Lectin_legB PF00139.19 CBK20955.2 - 3.2e-08 33.4 0.1 6.6e-08 32.4 0.1 1.5 1 1 0 1 1 1 1 Legume lectin domain Plus-3 PF03126.18 CBK20955.2 - 0.17 12.4 0.5 5.5 7.6 0.2 3.1 3 1 0 3 3 3 0 Plus-3 domain PTEN_C2 PF10409.9 CBK20956.2 - 4.2e-10 39.5 0.0 6.6e-10 38.9 0.0 1.2 1 0 0 1 1 1 1 C2 domain of PTEN tumour-suppressor protein ADP_ribosyl_GH PF03747.14 CBK20957.2 - 3.3e-56 191.2 0.5 3.8e-56 191.0 0.5 1.0 1 0 0 1 1 1 1 ADP-ribosylglycohydrolase Gly-zipper_Omp PF13488.6 CBK20957.2 - 0.089 12.8 4.1 5.1 7.2 0.9 2.5 2 0 0 2 2 2 0 Glycine zipper MFS_1 PF07690.16 CBK20958.2 - 8.4e-09 34.8 8.4 1.1e-08 34.5 8.4 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Yip1 PF04893.17 CBK20958.2 - 9.3 5.9 16.0 13 5.5 9.8 2.4 1 1 1 2 2 2 0 Yip1 domain ubiquitin PF00240.23 CBK20960.2 - 2.5e-34 116.8 0.5 3.6e-34 116.3 0.5 1.3 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_S30 PF04758.14 CBK20960.2 - 7.5e-27 93.3 7.4 1.3e-26 92.5 7.4 1.3 1 0 0 1 1 1 1 Ribosomal protein S30 Rad60-SLD PF11976.8 CBK20960.2 - 7.1e-16 57.8 0.6 1e-15 57.3 0.6 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 CBK20960.2 - 2.4e-05 24.7 0.1 9.1e-05 22.8 0.1 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain DUF2407 PF10302.9 CBK20960.2 - 0.00013 22.5 0.4 0.00023 21.7 0.4 1.4 1 1 0 1 1 1 1 DUF2407 ubiquitin-like domain Sde2_N_Ubi PF13019.6 CBK20960.2 - 0.001 18.9 0.3 0.0018 18.2 0.3 1.4 1 1 0 1 1 1 1 Silencing defective 2 N-terminal ubiquitin domain TBK1_ULD PF18396.1 CBK20960.2 - 0.0063 16.4 0.0 0.0093 15.9 0.0 1.3 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain Ubiquitin_5 PF18037.1 CBK20960.2 - 0.0078 16.6 0.0 0.015 15.6 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 CBK20960.2 - 0.0094 16.0 0.3 0.025 14.7 0.3 1.9 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_4 PF18036.1 CBK20960.2 - 0.26 11.4 5.2 4.9 7.3 0.2 2.5 3 0 0 3 3 3 0 Ubiquitin-like domain PH PF00169.29 CBK20961.2 - 3.4e-17 62.8 0.2 3.7e-17 62.7 0.2 1.0 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 CBK20961.2 - 9e-06 26.1 3.5 0.00037 20.9 3.5 2.0 1 1 0 1 1 1 1 Pleckstrin homology domain PH_8 PF15409.6 CBK20961.2 - 0.0002 21.6 0.1 0.00026 21.2 0.1 1.1 1 0 0 1 1 1 1 Pleckstrin homology domain PH_6 PF15406.6 CBK20961.2 - 0.00098 19.4 0.1 0.0015 18.8 0.0 1.4 1 1 0 1 1 1 1 Pleckstrin homology domain PH_9 PF15410.6 CBK20961.2 - 0.0017 18.7 0.3 0.032 14.6 0.3 2.0 1 1 0 1 1 1 1 Pleckstrin homology domain PH_13 PF16652.5 CBK20961.2 - 0.0064 16.3 0.0 0.0067 16.3 0.0 1.2 1 0 0 1 1 1 1 Pleckstrin homology domain PH_2 PF08458.10 CBK20961.2 - 0.028 14.8 0.0 0.031 14.6 0.0 1.1 1 0 0 1 1 1 0 Plant pleckstrin homology-like region Pex14_N PF04695.13 CBK20962.2 - 0.021 15.5 4.0 0.021 15.5 4.0 2.0 1 1 1 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region cNMP_binding PF00027.29 CBK20963.2 - 1.1e-08 35.0 0.0 2.7e-08 33.8 0.0 1.6 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Exo_endo_phos PF03372.23 CBK20963.2 - 0.00024 20.7 0.1 0.00036 20.1 0.1 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Dymeclin PF09742.9 CBK20964.2 - 5.4e-05 21.8 0.1 6e-05 21.7 0.1 1.0 1 0 0 1 1 1 1 Dyggve-Melchior-Clausen syndrome protein DUF2357 PF09823.9 CBK20965.2 - 0.0073 15.6 0.6 0.0083 15.4 0.6 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF2357) He_PIG PF05345.12 CBK20967.2 - 0.0014 18.7 0.5 0.0048 17.1 0.1 2.1 2 0 0 2 2 2 1 Putative Ig domain NifU PF01106.17 CBK20968.2 - 0.03 14.5 0.2 0.049 13.8 0.2 1.3 1 0 0 1 1 1 0 NifU-like domain DUF2012 PF09430.10 CBK20968.2 - 0.11 12.7 0.0 0.28 11.3 0.0 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2012) UEV PF05743.13 CBK20969.2 - 0.00021 21.2 0.1 0.0003 20.6 0.1 1.2 1 0 0 1 1 1 1 UEV domain Asn_synthase PF00733.21 CBK20969.2 - 0.078 12.6 0.1 0.14 11.7 0.0 1.4 2 0 0 2 2 2 0 Asparagine synthase Maf1 PF09174.10 CBK20971.2 - 1.2e-24 87.4 0.3 1.4e-24 87.2 0.3 1.1 1 0 0 1 1 1 1 Maf1 regulator DnaB PF00772.21 CBK20971.2 - 0.13 12.4 0.0 0.2 11.8 0.0 1.3 1 0 0 1 1 1 0 DnaB-like helicase N terminal domain TPR_1 PF00515.28 CBK20972.2 - 4.3e-44 146.6 26.6 2.1e-07 30.5 0.0 9.6 9 0 0 9 9 9 7 Tetratricopeptide repeat TPR_2 PF07719.17 CBK20972.2 - 6.6e-39 128.9 19.6 2.3e-05 24.2 0.9 9.6 9 0 0 9 9 9 7 Tetratricopeptide repeat TPR_11 PF13414.6 CBK20972.2 - 1.1e-32 111.5 14.8 1e-08 34.7 0.2 7.9 6 2 3 9 9 9 4 TPR repeat TPR_17 PF13431.6 CBK20972.2 - 7.1e-23 79.3 11.3 7.4e-06 26.0 0.0 8.3 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_16 PF13432.6 CBK20972.2 - 7.2e-19 68.2 1.4 4.1e-05 24.1 0.0 5.5 4 1 0 5 5 5 3 Tetratricopeptide repeat TPR_8 PF13181.6 CBK20972.2 - 7.3e-18 63.2 19.0 0.0032 17.6 0.0 8.8 9 0 0 9 9 8 5 Tetratricopeptide repeat TPR_14 PF13428.6 CBK20972.2 - 2.7e-14 52.6 8.4 0.24 12.3 0.0 8.9 5 3 5 10 10 9 3 Tetratricopeptide repeat TPR_12 PF13424.6 CBK20972.2 - 1.5e-12 47.6 20.6 4.3e-07 30.1 0.2 7.1 3 3 4 7 7 7 3 Tetratricopeptide repeat STI1 PF17830.1 CBK20972.2 - 5.9e-12 45.3 5.7 2.4e-10 40.2 1.2 3.4 4 0 0 4 4 2 1 STI1 domain TPR_9 PF13371.6 CBK20972.2 - 6.1e-11 42.3 3.1 0.0074 16.4 0.2 5.3 3 3 2 5 5 5 2 Tetratricopeptide repeat TPR_19 PF14559.6 CBK20972.2 - 2e-09 37.8 10.3 0.0029 18.1 0.0 6.3 5 2 2 7 7 6 3 Tetratricopeptide repeat DUF3147 PF11345.8 CBK20972.2 - 6e-06 26.6 21.8 7.9e-05 23.0 7.5 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF3147) TPR_7 PF13176.6 CBK20972.2 - 5.8e-05 22.8 2.2 17 5.7 0.0 6.3 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_20 PF14561.6 CBK20972.2 - 7e-05 23.1 1.3 4.8 7.6 0.0 4.0 3 1 0 3 3 3 1 Tetratricopeptide repeat BTAD PF03704.17 CBK20972.2 - 0.0053 17.2 7.4 2.2 8.7 0.1 4.3 2 1 2 4 4 4 1 Bacterial transcriptional activator domain TPR_10 PF13374.6 CBK20972.2 - 0.0068 16.2 20.1 0.16 11.9 0.0 7.5 8 0 0 8 8 8 1 Tetratricopeptide repeat CCDC53 PF10152.9 CBK20972.2 - 0.011 16.2 6.9 1.3 9.5 2.3 2.5 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex DUF4315 PF14193.6 CBK20972.2 - 0.041 13.9 3.2 0.067 13.2 1.3 2.5 2 0 0 2 2 1 0 Domain of unknown function (DUF4315) Fis1_TPR_C PF14853.6 CBK20972.2 - 0.05 13.7 7.4 3.7 7.7 0.1 4.5 4 1 1 5 5 4 0 Fis1 C-terminal tetratricopeptide repeat DUF1129 PF06570.11 CBK20972.2 - 1.9 8.0 7.9 0.31 10.5 3.8 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) Hum_adeno_E3A PF05393.11 CBK20972.2 - 2.1 8.4 6.3 9.5 6.3 6.5 2.0 1 1 0 1 1 1 0 Human adenovirus early E3A glycoprotein DUF3040 PF11239.8 CBK20972.2 - 2.5 8.4 5.4 15 6.0 0.0 4.6 5 0 0 5 5 5 0 Protein of unknown function (DUF3040) MIT PF04212.18 CBK20972.2 - 6.4 6.9 16.5 7.1 6.8 0.1 5.7 6 1 0 6 6 5 0 MIT (microtubule interacting and transport) domain RRM_1 PF00076.22 CBK20974.2 - 1.1e-27 95.6 2.4 2.3e-13 49.8 0.2 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CBK20974.2 - 3.7e-05 23.8 0.2 0.015 15.4 0.0 2.7 2 2 0 2 2 2 2 RNA recognition motif RNA_bind PF08675.11 CBK20974.2 - 0.00022 21.2 0.0 0.0012 18.8 0.0 2.2 2 1 0 2 2 2 1 RNA binding domain Nup35_RRM_2 PF14605.6 CBK20974.2 - 0.0032 17.4 0.1 0.034 14.2 0.1 2.2 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.11 CBK20974.2 - 0.011 15.8 0.3 0.03 14.3 0.2 1.8 2 1 0 2 2 2 0 RNA binding motif PHM7_cyt PF14703.6 CBK20974.2 - 0.013 15.7 0.0 8.9 6.5 0.0 3.0 2 1 1 3 3 3 0 Cytosolic domain of 10TM putative phosphate transporter OB_RNB PF08206.11 CBK20974.2 - 0.03 14.0 0.4 9.4 6.0 0.1 2.5 2 0 0 2 2 2 0 Ribonuclease B OB domain RL PF17797.1 CBK20974.2 - 0.053 13.5 0.1 0.091 12.7 0.1 1.4 1 0 0 1 1 1 0 RL domain Clathrin PF00637.20 CBK20976.2 - 2.4e-08 34.0 3.8 4e-05 23.5 0.1 3.8 4 1 0 4 4 4 2 Region in Clathrin and VPS Vps39_1 PF10366.9 CBK20976.2 - 2.7e-05 24.4 2.8 0.00021 21.5 0.5 2.7 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 1 Vps39_2 PF10367.9 CBK20976.2 - 0.0037 17.7 0.0 0.065 13.7 0.0 2.7 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 2 TPR_14 PF13428.6 CBK20976.2 - 0.0069 17.1 0.6 3.9 8.6 0.0 4.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 CBK20976.2 - 0.093 12.6 0.0 1.9 8.4 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat LSM PF01423.22 CBK20977.2 - 2e-16 59.4 0.9 2e-16 59.4 0.9 1.5 2 0 0 2 2 2 1 LSM domain SM-ATX PF14438.6 CBK20977.2 - 0.0081 16.3 0.0 0.014 15.5 0.0 1.4 1 0 0 1 1 1 1 Ataxin 2 SM domain Alpha_adaptin_C PF02296.16 CBK20977.2 - 0.13 12.5 1.0 0.29 11.3 0.1 1.8 2 0 0 2 2 2 0 Alpha adaptin AP2, C-terminal domain PAP2_C PF14360.6 CBK20978.2 - 1.2e-16 61.0 3.3 1.2e-16 61.0 3.3 3.5 3 0 0 3 3 3 1 PAP2 superfamily C-terminal PAP2 PF01569.21 CBK20978.2 - 0.00027 20.7 3.3 0.00027 20.7 3.3 2.8 2 1 1 3 3 3 1 PAP2 superfamily PAP2_3 PF14378.6 CBK20978.2 - 0.0031 17.2 0.6 0.0031 17.2 0.6 2.7 3 0 0 3 3 3 1 PAP2 superfamily DUF2981 PF11200.8 CBK20978.2 - 0.0059 16.4 0.8 0.0059 16.4 0.8 2.2 2 1 1 3 3 3 1 Protein of unknown function (DUF2981) ATP-grasp_5 PF13549.6 CBK20979.2 - 1.9e-56 191.0 0.7 3.1e-56 190.3 0.1 1.7 2 0 0 2 2 2 1 ATP-grasp domain Succ_CoA_lig PF13607.6 CBK20979.2 - 3.6e-39 133.7 0.0 6e-38 129.8 0.0 2.8 3 0 0 3 3 3 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.6 CBK20979.2 - 2.7e-22 79.4 0.1 7.5e-22 78.0 0.1 1.8 1 0 0 1 1 1 1 CoA binding domain CoA_binding PF02629.19 CBK20979.2 - 3.1e-08 34.2 2.6 9.3e-08 32.7 2.6 1.8 1 0 0 1 1 1 1 CoA binding domain mIF3 PF14877.6 CBK20979.2 - 0.02 14.6 0.1 0.043 13.5 0.1 1.5 1 0 0 1 1 1 0 Mitochondrial translation initiation factor Prefoldin PF02996.17 CBK20980.2 - 3.9e-12 46.1 2.9 5.3e-12 45.7 2.9 1.2 1 0 0 1 1 1 1 Prefoldin subunit DpnI_C PF17726.1 CBK20980.2 - 0.04 14.1 0.9 0.11 12.7 0.2 2.0 2 0 0 2 2 2 0 Dam-replacing HTH domain Prefoldin_2 PF01920.20 CBK20980.2 - 0.42 10.6 7.7 18 5.3 7.7 2.3 1 1 0 1 1 1 0 Prefoldin subunit DUF489 PF04356.12 CBK20980.2 - 0.6 10.1 5.0 3.7 7.5 5.0 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF489) AAA PF00004.29 CBK20981.2 - 7.6e-13 49.0 0.3 3e-12 47.1 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) BRCT PF00533.26 CBK20981.2 - 6.2e-07 29.7 0.0 5.5e-06 26.7 0.0 2.6 3 0 0 3 3 3 1 BRCA1 C Terminus (BRCT) domain RuvB_N PF05496.12 CBK20981.2 - 1.8e-06 27.8 0.0 3.1e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain Rad17 PF03215.15 CBK20981.2 - 2.4e-06 27.6 0.0 4.9e-06 26.6 0.0 1.6 1 1 0 1 1 1 1 Rad17 P-loop domain Zeta_toxin PF06414.12 CBK20981.2 - 0.00055 19.3 0.1 0.0013 18.1 0.0 1.6 2 0 0 2 2 2 1 Zeta toxin AAA_16 PF13191.6 CBK20981.2 - 0.00076 19.9 0.0 0.0017 18.8 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain NTPase_1 PF03266.15 CBK20981.2 - 0.00095 19.1 0.1 0.0052 16.7 0.0 2.1 1 1 1 2 2 2 1 NTPase RNA_helicase PF00910.22 CBK20981.2 - 0.001 19.4 0.0 0.0028 18.0 0.0 1.9 1 1 0 1 1 1 1 RNA helicase AAA_18 PF13238.6 CBK20981.2 - 0.001 19.6 0.1 0.0068 17.0 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 CBK20981.2 - 0.0018 18.4 0.0 0.0042 17.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.6 CBK20981.2 - 0.0021 18.1 0.0 0.0049 16.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 CBK20981.2 - 0.0025 17.5 0.1 0.0097 15.6 0.0 1.9 2 0 0 2 2 2 1 AAA domain PTCB-BRCT PF12738.7 CBK20981.2 - 0.0043 17.0 0.0 0.02 14.8 0.0 2.2 2 0 0 2 2 2 1 twin BRCT domain AAA_6 PF12774.7 CBK20981.2 - 0.0047 15.9 0.0 0.0075 15.3 0.0 1.4 1 0 0 1 1 1 1 Hydrolytic ATP binding site of dynein motor region AAA_22 PF13401.6 CBK20981.2 - 0.0064 16.8 0.0 0.014 15.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.6 CBK20981.2 - 0.0065 16.7 0.0 0.029 14.6 0.0 1.9 2 0 0 2 2 2 1 AAA domain TIP49 PF06068.13 CBK20981.2 - 0.0099 15.1 0.0 0.044 13.0 0.0 1.9 2 0 0 2 2 2 1 TIP49 P-loop domain NB-ARC PF00931.22 CBK20981.2 - 0.019 14.1 0.0 0.04 13.1 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain AAA_7 PF12775.7 CBK20981.2 - 0.028 14.0 0.0 0.056 12.9 0.0 1.5 1 1 0 1 1 1 0 P-loop containing dynein motor region DNA_pol3_delta PF06144.13 CBK20981.2 - 0.028 14.2 0.5 0.093 12.5 0.0 2.0 3 0 0 3 3 2 0 DNA polymerase III, delta subunit AAA_5 PF07728.14 CBK20981.2 - 0.034 14.2 0.0 0.073 13.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_17 PF13207.6 CBK20981.2 - 0.04 14.3 0.1 0.18 12.2 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_11 PF13086.6 CBK20981.2 - 0.045 13.5 0.5 0.58 9.9 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 CBK20981.2 - 0.059 13.1 0.0 0.1 12.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 CBK20981.2 - 0.081 13.4 1.4 0.26 11.8 0.1 2.4 1 1 1 2 2 2 0 ABC transporter SKI PF01202.22 CBK20981.2 - 0.092 12.9 0.2 0.32 11.1 0.0 2.0 2 1 1 3 3 2 0 Shikimate kinase Sigma54_activ_2 PF14532.6 CBK20981.2 - 0.096 12.8 0.0 0.71 10.0 0.0 2.3 1 1 0 1 1 1 0 Sigma-54 interaction domain TsaE PF02367.17 CBK20981.2 - 0.1 12.6 0.0 0.19 11.8 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE NACHT PF05729.12 CBK20981.2 - 0.15 12.0 0.1 0.48 10.3 0.0 2.1 2 1 0 2 2 1 0 NACHT domain RecX PF02631.16 CBK20982.2 - 0.069 13.6 4.4 0.087 13.3 4.4 1.1 1 0 0 1 1 1 0 RecX family UPF0242 PF06785.11 CBK20982.2 - 0.078 13.1 5.3 0.083 13.0 5.3 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Seryl_tRNA_N PF02403.22 CBK20982.2 - 0.26 11.5 7.2 0.27 11.5 6.5 1.4 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain E1_dh PF00676.20 CBK20982.2 - 0.36 9.7 4.2 0.24 10.3 2.7 1.4 1 1 1 2 2 2 0 Dehydrogenase E1 component TBCC_N PF16752.5 CBK20982.2 - 0.4 11.1 6.8 0.38 11.2 5.7 1.5 1 1 0 1 1 1 0 Tubulin-specific chaperone C N-terminal domain Ribosomal_60s PF00428.19 CBK20983.2 - 1.6e-15 57.5 15.0 1.8e-15 57.3 15.0 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein DUF3824 PF12868.7 CBK20983.2 - 0.0059 17.3 2.0 0.0067 17.1 2.0 1.0 1 0 0 1 1 1 1 Domain of unknwon function (DUF3824) FYDLN_acid PF09538.10 CBK20983.2 - 0.041 14.5 4.4 0.045 14.4 4.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) Myc_N PF01056.18 CBK20983.2 - 0.14 12.1 3.8 0.14 12.0 3.8 1.1 1 0 0 1 1 1 0 Myc amino-terminal region OCC1 PF15506.6 CBK20983.2 - 0.21 11.7 3.1 0.29 11.3 3.1 1.2 1 0 0 1 1 1 0 OCC1 family DNA_pol_phi PF04931.13 CBK20983.2 - 0.21 9.6 3.6 0.18 9.8 3.6 1.0 1 0 0 1 1 1 0 DNA polymerase phi Cytomega_UL84 PF06284.11 CBK20983.2 - 0.32 9.4 3.7 0.31 9.5 3.7 1.0 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein MscS_TM PF12794.7 CBK20983.2 - 6 5.6 5.1 6.9 5.4 5.1 1.1 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 GMP_synt_C PF00958.22 CBK20984.2 - 6.6e-43 144.7 0.0 1.6e-42 143.4 0.0 1.7 1 0 0 1 1 1 1 GMP synthase C terminal domain GATase PF00117.28 CBK20984.2 - 2.4e-34 118.8 0.0 3.5e-34 118.2 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I NAD_synthase PF02540.17 CBK20984.2 - 2.9e-09 36.4 0.1 4.3e-05 22.7 0.1 2.4 2 0 0 2 2 2 2 NAD synthase Peptidase_C26 PF07722.13 CBK20984.2 - 1.3e-06 28.4 0.2 4e-06 26.7 0.2 1.9 1 1 0 1 1 1 1 Peptidase C26 tRNA_Me_trans PF03054.16 CBK20984.2 - 0.0008 18.3 0.3 0.0035 16.2 0.2 1.9 2 0 0 2 2 2 1 tRNA methyl transferase ThiI PF02568.14 CBK20984.2 - 0.0046 16.6 0.1 0.012 15.2 0.1 1.7 2 0 0 2 2 2 1 Thiamine biosynthesis protein (ThiI) SNO PF01174.19 CBK20984.2 - 0.0077 16.1 0.0 0.071 13.0 0.0 2.2 2 0 0 2 2 2 1 SNO glutamine amidotransferase family QueC PF06508.13 CBK20984.2 - 0.018 14.5 0.0 0.79 9.2 0.0 2.2 1 1 0 1 1 1 0 Queuosine biosynthesis protein QueC Alg6_Alg8 PF03155.15 CBK20985.2 - 1.3e-123 413.5 25.1 1.7e-123 413.2 25.1 1.0 1 0 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family GT87 PF09594.10 CBK20985.2 - 1.2e-05 25.1 5.1 1.2e-05 25.1 5.1 1.7 2 0 0 2 2 2 1 Glycosyltransferase family 87 LRR_4 PF12799.7 CBK20986.2 - 0.0033 17.8 20.0 0.63 10.6 0.1 6.6 3 2 4 7 7 7 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CBK20986.2 - 0.0069 16.1 8.7 0.081 12.7 0.0 4.8 4 2 1 5 5 5 2 Leucine rich repeat DNA_pol_B_2 PF03175.13 CBK20987.2 - 1.3e-16 60.5 13.5 4.9e-14 52.1 9.4 2.4 2 0 0 2 2 2 2 DNA polymerase type B, organellar and viral DNA_pol_B_2 PF03175.13 CBK20988.2 - 9e-17 61.1 12.8 3.1e-14 52.7 8.7 2.3 2 0 0 2 2 2 2 DNA polymerase type B, organellar and viral He_PIG PF05345.12 CBK20989.2 - 9.1e-18 64.2 25.6 5e-05 23.4 0.1 5.1 5 0 0 5 5 5 4 Putative Ig domain DUF11 PF01345.18 CBK20989.2 - 6.8e-06 26.3 0.0 0.97 9.8 0.0 4.4 2 2 1 3 3 3 2 Domain of unknown function DUF11 I-set PF07679.16 CBK20989.2 - 0.00092 19.2 6.6 2.5 8.2 0.1 4.4 4 0 0 4 4 4 2 Immunoglobulin I-set domain DUF3185 PF11381.8 CBK20989.2 - 0.084 12.9 4.8 0.24 11.4 4.8 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3185) FeS_assembly_P PF01883.19 CBK20989.2 - 0.18 12.0 0.3 10 6.4 0.0 3.1 3 0 0 3 3 3 0 Iron-sulfur cluster assembly protein HRM PF02793.22 CBK20989.2 - 0.35 11.2 13.0 5.2 7.4 0.1 5.1 5 0 0 5 5 5 0 Hormone receptor domain Arch_flagellin PF01917.16 CBK20989.2 - 2.7 8.1 9.2 8.3 6.6 4.3 3.3 2 1 0 2 2 2 0 Archaebacterial flagellin CPW_WPC PF09717.10 CBK20989.2 - 8.1 7.5 8.2 9.7 7.3 0.1 3.8 4 0 0 4 4 4 0 Plasmodium falciparum domain of unknown function (CPW_WPC) Peptidase_S8 PF00082.22 CBK20990.2 - 1.7e-40 139.2 1.7 2.1e-40 138.9 1.7 1.1 1 0 0 1 1 1 1 Subtilase family PAP2_C PF14360.6 CBK20991.2 - 4.3e-16 59.2 1.6 4.3e-16 59.2 1.6 3.3 3 0 0 3 3 3 1 PAP2 superfamily C-terminal PAP2 PF01569.21 CBK20991.2 - 3.3e-07 30.2 0.7 3.3e-07 30.2 0.7 3.0 3 0 0 3 3 3 1 PAP2 superfamily PAP2_3 PF14378.6 CBK20991.2 - 0.00031 20.5 3.9 0.00031 20.5 3.9 2.5 2 1 0 2 2 2 1 PAP2 superfamily Caps_synth_CapC PF14102.6 CBK20991.2 - 0.34 11.4 5.6 0.094 13.1 0.7 2.4 3 0 0 3 3 3 0 Capsule biosynthesis CapC Peptidase_M50B PF13398.6 CBK20991.2 - 4 7.0 9.5 9.2 5.8 0.2 3.0 3 0 0 3 3 3 0 Peptidase M50B-like RDD PF06271.12 CBK20991.2 - 7.9 6.7 13.4 0.092 12.9 2.5 2.6 2 2 0 2 2 2 0 RDD family Vip3A_N PF12495.8 CBK20992.2 - 0.33 10.8 6.3 1.2 9.0 0.1 2.4 2 0 0 2 2 2 0 Vegetative insecticide protein 3A N terminal Med25 PF11232.8 CBK20992.2 - 0.35 10.8 4.2 2.3 8.2 0.6 2.6 2 0 0 2 2 2 0 Mediator complex subunit 25 PTOV activation and synapsin 2 SARAF PF06682.12 CBK20993.2 - 1.4e-52 179.4 0.1 1.7e-52 179.1 0.1 1.1 1 0 0 1 1 1 1 SOCE-associated regulatory factor of calcium homoeostasis zf-NF-X1 PF01422.17 CBK20994.2 - 2.6e-11 43.3 283.0 6.3e-07 29.3 13.9 15.5 15 0 0 15 15 15 11 NF-X1 type zinc finger MORN PF02493.20 CBK20995.2 - 5.7e-07 29.1 35.1 3.6e-06 26.5 1.2 5.9 6 1 0 6 6 6 4 MORN repeat MORN_2 PF07661.13 CBK20995.2 - 0.021 15.0 16.3 0.78 10.2 0.8 4.4 4 0 0 4 4 4 0 MORN repeat variant DUF4064 PF13273.6 CBK20996.2 - 0.00097 19.4 0.0 0.026 14.8 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF4064) DUF4448 PF14610.6 CBK20996.2 - 0.0049 16.7 0.1 0.005 16.6 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) MFS_2 PF13347.6 CBK20996.2 - 0.017 13.7 0.0 0.028 13.0 0.0 1.3 1 0 0 1 1 1 0 MFS/sugar transport protein FeoB_associated PF12669.7 CBK20996.2 - 0.028 14.8 2.4 0.044 14.2 2.4 1.3 1 0 0 1 1 1 0 FeoB-associated Cys-rich membrane protein CcmH PF03918.14 CBK20996.2 - 0.039 13.2 0.0 0.065 12.5 0.0 1.3 1 0 0 1 1 1 0 Cytochrome C biogenesis protein DUF485 PF04341.12 CBK20996.2 - 0.068 13.1 0.3 0.3 11.1 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function, DUF485 DUF2754 PF10953.8 CBK20996.2 - 0.17 12.1 0.3 0.17 12.1 0.3 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2754) ABC2_membrane_3 PF12698.7 CBK20996.2 - 0.29 10.2 3.3 0.77 8.8 3.3 1.9 1 1 0 1 1 1 0 ABC-2 family transporter protein DUF5305 PF17231.2 CBK20996.2 - 0.58 9.5 2.3 0.47 9.8 0.9 1.6 1 1 0 1 1 1 0 Family of unknown function (DUF5305) MGC-24 PF05283.11 CBK20996.2 - 4.7 7.6 13.7 0.39 11.2 1.1 2.1 1 1 1 2 2 2 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin Collectrin PF16959.5 CBK20996.2 - 5.8 6.7 5.5 0.46 10.3 0.5 1.8 2 0 0 2 2 2 0 Renal amino acid transporter XPG_I PF00867.18 CBK20997.2 - 2.5e-27 95.1 0.0 1.2e-26 92.8 0.0 2.3 1 0 0 1 1 1 1 XPG I-region XPG_I_2 PF12813.7 CBK20997.2 - 0.00019 21.0 0.0 0.00045 19.8 0.0 1.7 1 0 0 1 1 1 1 XPG domain containing DUF1043 PF06295.12 CBK20997.2 - 0.094 12.7 0.1 0.094 12.7 0.1 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1043) XPG_N PF00752.17 CBK20998.2 - 2.8e-29 101.5 0.0 3.9e-29 101.1 0.0 1.2 1 0 0 1 1 1 1 XPG N-terminal domain XRN_N PF03159.18 CBK20998.2 - 0.0015 18.1 0.0 0.0015 18.0 0.0 1.1 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus PS_Dcarbxylase PF02666.15 CBK20999.2 - 1.4e-52 178.2 0.0 2.3e-52 177.5 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase Fe-ADH PF00465.19 CBK21000.2 - 6.2e-77 258.9 0.0 6.9e-77 258.7 0.0 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.6 CBK21000.2 - 2.3e-06 27.5 0.1 0.0045 16.7 0.0 2.2 2 0 0 2 2 2 2 Iron-containing alcohol dehydrogenase CbiK PF06180.11 CBK21000.2 - 0.0052 16.1 0.0 0.008 15.5 0.0 1.3 1 0 0 1 1 1 1 Cobalt chelatase (CbiK) DHQ_synthase PF01761.20 CBK21000.2 - 0.035 13.3 0.1 0.16 11.1 0.1 2.1 2 0 0 2 2 2 0 3-dehydroquinate synthase HSP70 PF00012.20 CBK21001.2 - 3.4e-66 223.7 2.7 3.8e-66 223.6 2.7 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 CBK21001.2 - 5.1e-12 45.2 0.4 4.6e-11 42.1 0.1 2.3 2 1 0 2 2 2 1 MreB/Mbl protein baeRF_family5 PF18846.1 CBK21001.2 - 0.24 11.6 1.6 0.28 11.4 0.1 1.8 3 0 0 3 3 3 0 Bacterial archaeo-eukaryotic release factor family 5 ToxB_N PF18224.1 CBK21001.2 - 2.3 8.2 5.5 3.4 7.7 1.1 3.1 2 2 1 3 3 3 0 ToxB N-terminal domain E1-E2_ATPase PF00122.20 CBK21002.2 - 3.4e-51 173.3 0.0 3.4e-51 173.3 0.0 2.8 3 0 0 3 3 3 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 CBK21002.2 - 6.5e-49 166.1 0.3 6.5e-49 166.1 0.3 1.9 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 CBK21002.2 - 1.7e-20 74.2 1.1 6.9e-20 72.2 1.1 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 CBK21002.2 - 5.3e-16 58.1 0.6 1.9e-15 56.3 0.0 2.2 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 CBK21002.2 - 9.3e-15 54.5 0.0 1.8e-14 53.6 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 CBK21002.2 - 0.0001 22.1 0.8 0.00045 20.0 0.4 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 CBK21002.2 - 0.0032 17.9 0.1 0.012 16.0 0.1 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase ADK PF00406.22 CBK21003.2 - 5e-27 94.9 0.0 6.2e-27 94.5 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase ADK_lid PF05191.14 CBK21003.2 - 1.5e-14 53.7 0.9 2.4e-14 53.0 0.9 1.3 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_17 PF13207.6 CBK21003.2 - 2.7e-05 24.6 0.0 4.1e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain GFA PF04828.14 CBK21003.2 - 0.067 13.5 0.1 2.4 8.6 0.0 2.2 1 1 1 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme SAS-6_N PF16531.5 CBK21004.2 - 7.8e-14 52.0 2.1 8.5e-14 51.9 0.4 2.0 2 0 0 2 2 2 1 Centriolar protein SAS N-terminal GAS PF13851.6 CBK21004.2 - 0.02 14.2 44.7 0.18 11.1 11.6 3.4 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding DUF2935 PF11155.8 CBK21004.2 - 0.22 11.9 8.0 0.2 12.0 1.3 3.0 1 1 0 2 2 2 0 Domain of unknown function (DUF2935) Raptor_N PF14538.6 CBK21004.2 - 1.2 9.1 5.2 1.8 8.5 0.2 2.7 3 0 0 3 3 3 0 Raptor N-terminal CASPase like domain DUF4686 PF15742.5 CBK21004.2 - 2.7 7.1 50.8 0.095 11.8 30.9 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4686) DUF3584 PF12128.8 CBK21004.2 - 3.5 5.0 50.0 0.054 11.0 34.7 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) CENP-F_leu_zip PF10473.9 CBK21004.2 - 4.6 7.3 47.6 0.027 14.5 18.0 3.7 2 1 2 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DHR10 PF18595.1 CBK21004.2 - 4.8 7.3 55.3 2.1 8.4 36.1 3.8 1 1 2 3 3 3 0 Designed helical repeat protein 10 domain Filament PF00038.21 CBK21004.2 - 4.9 6.6 40.2 2.3 7.7 20.4 3.0 1 1 1 2 2 2 0 Intermediate filament protein DUF3450 PF11932.8 CBK21004.2 - 5.2 6.3 45.0 0.23 10.7 21.5 3.1 1 1 2 3 3 3 0 Protein of unknown function (DUF3450) Phage_GP20 PF06810.11 CBK21004.2 - 5.5 6.8 38.0 6.1 6.6 19.6 3.3 1 1 2 3 3 3 0 Phage minor structural protein GP20 TFIIA PF03153.13 CBK21004.2 - 7.6 6.4 22.2 11 5.9 22.2 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit dCache_1 PF02743.18 CBK21004.2 - 9.8 5.9 13.5 0.99 9.1 2.7 2.6 2 0 0 2 2 2 0 Cache domain COG6 PF06419.11 CBK21005.2 - 1e-58 199.1 14.2 1.7e-54 185.2 13.6 2.2 2 0 0 2 2 2 2 Conserved oligomeric complex COG6 LRR_8 PF13855.6 CBK21006.2 - 0.0013 18.4 4.9 1.8 8.4 0.0 5.9 7 1 0 7 7 7 2 Leucine rich repeat RRM_1 PF00076.22 CBK21007.2 - 0.00012 21.8 0.0 0.00022 21.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) eIF2A PF08662.11 CBK21008.2 - 6.6e-35 120.8 0.0 3.8e-33 115.0 0.0 2.9 2 1 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A ANAPC4_WD40 PF12894.7 CBK21008.2 - 3.4e-05 24.0 0.1 1.6 9.1 0.0 5.4 3 1 2 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain RRM_1 PF00076.22 CBK21008.2 - 0.00068 19.4 0.0 0.0016 18.2 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Cwf_Cwc_15 PF04889.12 CBK21008.2 - 0.0015 18.3 0.7 0.0025 17.6 0.7 1.2 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein Coatomer_WDAD PF04053.14 CBK21008.2 - 0.0042 16.2 0.0 0.93 8.5 0.0 2.9 1 1 2 3 3 3 2 Coatomer WD associated region WD40 PF00400.32 CBK21008.2 - 0.13 13.2 6.4 1.2 10.2 0.1 4.7 6 0 0 6 6 6 0 WD domain, G-beta repeat GST_C_2 PF13410.6 CBK21008.2 - 0.28 11.3 1.3 4.2 7.5 0.1 3.1 4 0 0 4 4 4 0 Glutathione S-transferase, C-terminal domain TFIIIC_delta PF12657.7 CBK21008.2 - 0.34 10.8 2.5 54 3.6 0.5 4.4 3 2 1 4 4 4 0 Transcription factor IIIC subunit delta N-term Cation_efflux PF01545.21 CBK21009.2 - 5.8e-49 166.5 10.8 6.9e-49 166.3 10.8 1.1 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 CBK21009.2 - 2.9e-15 56.2 1.8 4.6e-15 55.5 1.8 1.3 1 0 0 1 1 1 1 Dimerisation domain of Zinc Transporter Asp23 PF03780.13 CBK21009.2 - 0.036 14.5 1.3 0.099 13.1 1.3 1.7 1 0 0 1 1 1 0 Asp23 family, cell envelope-related function TspO_MBR PF03073.15 CBK21009.2 - 3.4 7.7 9.8 9.8 6.2 9.7 2.0 1 1 0 1 1 1 0 TspO/MBR family Aa_trans PF01490.18 CBK21010.2 - 3.9e-30 104.9 24.5 4.4e-30 104.7 24.5 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Cytochrom_B_C PF00032.17 CBK21010.2 - 9.5 6.6 11.3 2.6 8.4 0.6 3.4 2 1 0 2 2 2 0 Cytochrome b(C-terminal)/b6/petD RTP1_C1 PF10363.9 CBK21011.2 - 1.8e-25 89.3 0.4 1.5e-24 86.3 0.1 2.7 3 0 0 3 3 3 1 Required for nuclear transport of RNA pol II C-terminus 1 MMS19_C PF12460.8 CBK21011.2 - 0.0005 19.3 2.6 0.00056 19.1 0.7 1.9 2 0 0 2 2 2 1 RNAPII transcription regulator C-terminal Adaptin_N PF01602.20 CBK21011.2 - 0.002 16.8 0.6 0.014 14.0 0.1 2.2 2 0 0 2 2 2 1 Adaptin N terminal region RTP1_C2 PF10304.9 CBK21011.2 - 0.0044 16.7 0.5 0.012 15.3 0.5 1.8 1 0 0 1 1 1 1 Required for nuclear transport of RNA pol II C-terminus 2 HEAT PF02985.22 CBK21011.2 - 0.0053 16.9 3.4 10 6.7 0.0 5.2 4 1 0 4 4 4 1 HEAT repeat HEAT_2 PF13646.6 CBK21011.2 - 0.021 15.2 9.2 0.039 14.4 0.1 3.5 3 1 0 3 3 3 0 HEAT repeats ParcG PF10274.9 CBK21011.2 - 0.027 14.6 0.0 0.069 13.3 0.0 1.7 1 0 0 1 1 1 0 Parkin co-regulated protein HEAT_EZ PF13513.6 CBK21011.2 - 0.032 14.7 2.0 2.2 8.9 0.0 3.4 3 0 0 3 3 3 0 HEAT-like repeat Sugar_tr PF00083.24 CBK21012.2 - 1.4e-36 126.4 19.7 3.2e-35 121.9 19.7 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CBK21012.2 - 4e-12 45.7 18.6 5.2e-12 45.4 18.6 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.6 CBK21012.2 - 7.7e-08 31.3 15.4 0.00019 20.2 0.4 2.1 1 1 1 2 2 2 2 MFS/sugar transport protein Ribosomal_L30 PF00327.20 CBK21013.2 - 1.2e-20 73.1 1.8 2.7e-20 72.0 1.8 1.6 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e Ribosomal_L30_N PF08079.12 CBK21013.2 - 7.1e-18 64.6 7.3 1.4e-17 63.7 7.3 1.5 1 0 0 1 1 1 1 Ribosomal L30 N-terminal domain DivIVA PF05103.13 CBK21013.2 - 0.22 11.6 5.4 0.36 10.9 5.4 1.4 1 0 0 1 1 1 0 DivIVA protein Ribosomal_L19e PF01280.20 CBK21015.2 - 2.1e-57 193.2 11.9 2.7e-57 192.9 11.9 1.1 1 0 0 1 1 1 1 Ribosomal protein L19e PP2C PF00481.21 CBK21016.2 - 9.4e-32 110.6 0.0 1.5e-31 110.0 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 CBK21016.2 - 2.9e-08 33.6 0.0 6.3e-08 32.5 0.0 1.5 1 1 0 1 1 1 1 Protein phosphatase 2C B12-binding_2 PF02607.17 CBK21016.2 - 0.17 12.3 0.3 1.6 9.2 0.2 2.2 2 0 0 2 2 2 0 B12 binding domain Thymidylate_kin PF02223.17 CBK21017.2 - 3.8e-44 150.6 0.0 4.3e-44 150.4 0.0 1.0 1 0 0 1 1 1 1 Thymidylate kinase PRK PF00485.18 CBK21017.2 - 0.0049 16.6 0.0 0.0076 16.0 0.0 1.2 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_35 PF14516.6 CBK21017.2 - 0.019 13.8 0.0 0.023 13.6 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain AAA_18 PF13238.6 CBK21017.2 - 0.039 14.5 0.0 0.064 13.8 0.0 1.7 1 1 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 CBK21017.2 - 0.073 13.0 0.0 0.1 12.5 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_22 PF13401.6 CBK21017.2 - 0.16 12.2 0.0 0.3 11.4 0.0 1.8 1 1 0 1 1 1 0 AAA domain NTF2 PF02136.20 CBK21020.2 - 3.6e-14 53.4 0.0 4.1e-14 53.2 0.0 1.1 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain Adaptin_N PF01602.20 CBK21021.2 - 2.3e-121 405.9 9.3 2.7e-121 405.7 9.3 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 CBK21021.2 - 7.4e-61 204.9 10.3 3.5e-57 193.0 0.2 3.6 3 1 0 4 4 4 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 CBK21021.2 - 1e-16 61.1 3.8 1.7e-05 25.1 0.0 5.3 3 1 2 5 5 5 3 HEAT repeats HEAT PF02985.22 CBK21021.2 - 3.4e-08 33.0 10.6 0.73 10.3 0.0 7.6 7 0 0 7 7 7 3 HEAT repeat Cnd3 PF12719.7 CBK21021.2 - 6.9e-08 32.0 3.9 4.7e-05 22.7 0.3 2.4 2 0 0 2 2 2 2 Nuclear condensing complex subunits, C-term domain CLASP_N PF12348.8 CBK21021.2 - 0.00013 21.6 0.1 0.17 11.5 0.0 3.2 2 1 1 3 3 3 2 CLASP N terminal Arm PF00514.23 CBK21021.2 - 0.0058 16.6 1.4 16 5.7 0.1 4.6 6 0 0 6 6 6 1 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 CBK21021.2 - 0.024 15.2 7.2 4.3 7.9 0.0 5.3 6 1 1 7 7 7 0 HEAT-like repeat HEAT_PBS PF03130.16 CBK21021.2 - 0.11 13.2 0.1 16 6.6 0.0 3.5 2 0 0 2 2 2 0 PBS lyase HEAT-like repeat RRN3 PF05327.11 CBK21021.2 - 2.9 6.3 6.6 8.3 4.8 6.6 1.8 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Peptidase_M24 PF00557.24 CBK21022.2 - 9.4e-51 172.5 0.1 1.4e-50 171.9 0.1 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.16 CBK21022.2 - 2.4e-27 95.1 0.0 5.4e-27 94.0 0.0 1.6 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain DUF3793 PF12672.7 CBK21022.2 - 0.12 12.4 0.1 0.22 11.6 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3793) C2 PF00168.30 CBK21024.2 - 0.055 13.8 0.1 0.09 13.1 0.1 1.3 1 0 0 1 1 1 0 C2 domain VPS38 PF17649.1 CBK21024.2 - 0.27 10.1 3.5 0.67 8.8 3.6 1.8 1 1 0 1 1 1 0 Vacuolar protein sorting 38 MazG-like PF12643.7 CBK21026.2 - 7.8e-10 38.9 0.0 1.2e-09 38.2 0.0 1.3 1 0 0 1 1 1 1 MazG-like family MazG PF03819.17 CBK21026.2 - 1.7e-06 28.1 0.0 3.7e-06 27.0 0.0 1.7 1 1 0 1 1 1 1 MazG nucleotide pyrophosphohydrolase domain MitMem_reg PF13012.6 CBK21027.2 - 1.3e-22 80.4 4.8 1.9e-22 79.8 2.4 2.1 2 0 0 2 2 2 1 Maintenance of mitochondrial structure and function JAB PF01398.21 CBK21027.2 - 4.5e-20 71.8 0.3 9.4e-20 70.8 0.0 1.7 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease CUE PF02845.16 CBK21027.2 - 0.059 13.1 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 CUE domain HJURP_C PF12347.8 CBK21027.2 - 0.068 13.2 0.0 0.2 11.7 0.0 1.8 1 0 0 1 1 1 0 Holliday junction regulator protein family C-terminal repeat AAA_assoc_2 PF16193.5 CBK21027.2 - 0.15 12.4 0.4 0.3 11.4 0.4 1.6 1 1 0 1 1 1 0 AAA C-terminal domain CAMP_factor PF07373.11 CBK21027.2 - 0.15 11.6 1.1 0.29 10.7 0.4 1.8 2 0 0 2 2 2 0 CAMP factor (Cfa) WD40 PF00400.32 CBK21028.2 - 1.4e-24 85.9 5.2 0.00073 20.3 0.0 6.3 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBK21028.2 - 8.6e-09 35.6 0.1 0.093 13.0 0.1 4.7 1 1 4 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 CBK21028.2 - 1.7e-05 23.7 4.5 0.11 11.1 0.3 3.4 1 1 3 4 4 4 3 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 CBK21028.2 - 0.02 13.6 0.6 1.2 7.7 0.1 3.1 1 1 2 3 3 3 0 Nup133 N terminal like Nbas_N PF15492.6 CBK21028.2 - 0.065 12.5 0.0 3.8 6.8 0.0 2.8 2 1 1 3 3 3 0 Neuroblastoma-amplified sequence, N terminal Hira PF07569.11 CBK21028.2 - 0.13 12.0 2.5 9.7 5.8 0.0 3.7 1 1 2 4 4 4 0 TUP1-like enhancer of split Ras PF00071.22 CBK21029.2 - 1.1e-49 168.1 0.5 1.3e-49 168.0 0.5 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CBK21029.2 - 8.7e-32 109.9 0.2 1.3e-31 109.3 0.2 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CBK21029.2 - 6.1e-13 48.6 0.1 8e-13 48.2 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 CBK21029.2 - 1e-05 25.6 0.0 1.4e-05 25.1 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 CBK21029.2 - 3.6e-05 23.2 0.2 5.1e-05 22.7 0.2 1.3 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 CBK21029.2 - 0.00011 22.1 0.0 0.28 11.1 0.0 2.1 2 0 0 2 2 2 2 RsgA GTPase SRPRB PF09439.10 CBK21029.2 - 0.00023 20.7 0.1 0.0089 15.5 0.0 2.0 1 1 1 2 2 2 2 Signal recognition particle receptor beta subunit Glucodextran_N PF09137.11 CBK21029.2 - 0.043 13.4 0.1 0.051 13.1 0.1 1.1 1 0 0 1 1 1 0 Glucodextranase, domain N AAA_33 PF13671.6 CBK21029.2 - 0.12 12.5 0.0 0.23 11.6 0.0 1.5 1 1 0 1 1 1 0 AAA domain eIF-5_eIF-2B PF01873.17 CBK21030.2 - 1.3e-33 115.3 0.0 2.7e-33 114.3 0.0 1.5 1 0 0 1 1 1 1 Domain found in IF2B/IF5 zf-LITAF-like PF10601.9 CBK21030.2 - 0.044 14.1 1.9 0.1 12.9 1.9 1.6 1 0 0 1 1 1 0 LITAF-like zinc ribbon domain SelP_N PF04592.14 CBK21030.2 - 0.096 12.1 9.2 0.14 11.6 9.2 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Neur_chan_memb PF02932.16 CBK21030.2 - 0.17 11.9 2.2 0.2 11.7 2.2 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Hep_59 PF07052.11 CBK21030.2 - 0.86 10.4 7.5 1.1 10.1 5.9 1.9 2 0 0 2 2 2 0 Hepatocellular carcinoma-associated antigen 59 DUF2387 PF09526.10 CBK21030.2 - 1.1 9.4 3.8 0.52 10.5 0.3 2.2 2 1 0 3 3 3 0 Probable metal-binding protein (DUF2387) DUF3797 PF12677.7 CBK21030.2 - 1.5 8.7 5.6 7.2 6.6 0.1 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF3797) ALMT PF11744.8 CBK21030.2 - 2.7 6.7 4.4 3.7 6.3 4.4 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter Zip PF02535.22 CBK21030.2 - 8.4 5.5 5.4 11 5.2 5.4 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter IBN_N PF03810.19 CBK21031.2 - 9.9e-05 22.2 1.8 0.0027 17.6 0.0 3.7 3 1 1 4 4 4 1 Importin-beta N-terminal domain HEAT PF02985.22 CBK21031.2 - 0.012 15.8 0.0 0.21 12.0 0.0 3.4 1 0 0 1 1 1 0 HEAT repeat Xpo1 PF08389.12 CBK21031.2 - 0.21 11.7 0.1 0.21 11.7 0.1 4.9 6 2 0 6 6 6 0 Exportin 1-like protein Peptidase_C1 PF00112.23 CBK21032.2 - 4.2e-69 233.0 2.3 8.8e-69 231.9 2.3 1.6 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 CBK21032.2 - 4.8e-08 33.3 4.8 1.1e-07 32.1 4.8 1.7 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) GAS PF13851.6 CBK21033.2 - 0.00079 18.8 95.3 0.053 12.9 13.1 8.1 6 2 2 8 8 8 5 Growth-arrest specific micro-tubule binding Cast PF10174.9 CBK21033.2 - 0.0019 16.5 29.8 0.0019 16.5 29.8 3.4 3 0 0 3 3 3 1 RIM-binding protein of the cytomatrix active zone DUF4201 PF13870.6 CBK21033.2 - 0.0085 15.8 22.0 0.0085 15.8 22.0 7.0 5 2 3 8 8 8 2 Domain of unknown function (DUF4201) YabA PF06156.13 CBK21033.2 - 0.014 16.0 2.8 0.014 16.0 2.8 8.4 6 2 3 9 9 9 0 Initiation control protein YabA Cnn_1N PF07989.11 CBK21033.2 - 0.016 15.3 4.9 0.016 15.3 4.9 8.8 6 1 2 8 8 8 0 Centrosomin N-terminal motif 1 TUDOR PF00567.24 CBK21033.2 - 0.092 12.8 0.2 0.092 12.8 0.2 3.1 4 0 0 4 4 4 0 Tudor domain Spc42p PF11544.8 CBK21033.2 - 0.16 12.0 0.2 0.16 12.0 0.2 6.3 5 1 0 5 5 5 0 Spindle pole body component Spc42p FUSC PF04632.12 CBK21033.2 - 1.1 7.8 16.2 1.1 7.8 3.3 3.4 1 1 2 4 4 4 0 Fusaric acid resistance protein family EzrA PF06160.12 CBK21033.2 - 9.8 4.2 73.6 0.078 11.1 30.0 4.2 3 1 0 3 3 3 0 Septation ring formation regulator, EzrA HSP20 PF00011.21 CBK21034.2 - 3.4e-12 46.4 0.0 3.6e-12 46.3 0.0 1.0 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 CBK21034.2 - 0.069 12.7 0.0 0.09 12.3 0.0 1.4 1 1 0 1 1 1 0 HSP20-like domain found in ArsA Mito_carr PF00153.27 CBK21035.2 - 1.2e-55 185.4 2.3 4.2e-18 65.1 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Fuseless PF15993.5 CBK21035.2 - 0.072 12.3 0.4 0.17 11.0 0.1 1.7 1 1 1 2 2 2 0 Fuseless Sulf_transp PF04143.14 CBK21036.2 - 9.1e-35 120.7 25.5 1e-34 120.5 25.5 1.0 1 0 0 1 1 1 1 Sulphur transport DUF1182 PF06681.13 CBK21036.2 - 0.071 12.7 1.1 0.16 11.5 1.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1182) AOX PF01786.17 CBK21036.2 - 0.097 12.2 0.1 0.17 11.5 0.1 1.3 1 0 0 1 1 1 0 Alternative oxidase IF-2B PF01008.17 CBK21038.2 - 2.7e-37 128.5 0.0 3.2e-37 128.3 0.0 1.1 1 0 0 1 1 1 1 Initiation factor 2 subunit family DUF676 PF05057.14 CBK21039.2 - 4.6e-21 75.3 0.0 8.3e-21 74.5 0.0 1.4 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Palm_thioest PF02089.15 CBK21039.2 - 0.00078 19.4 0.0 0.0012 18.8 0.0 1.3 1 0 0 1 1 1 1 Palmitoyl protein thioesterase PGAP1 PF07819.13 CBK21039.2 - 0.014 15.1 0.1 0.041 13.6 0.1 1.9 1 1 0 1 1 1 0 PGAP1-like protein ESP PF16590.5 CBK21039.2 - 0.071 13.4 0.0 0.21 11.8 0.0 1.8 1 0 0 1 1 1 0 Exocrine gland-secreting peptide zf-RanBP PF00641.18 CBK21039.2 - 0.16 11.3 3.0 0.35 10.2 3.0 1.5 1 0 0 1 1 1 0 Zn-finger in Ran binding protein and others Phosphodiest PF01663.22 CBK21040.2 - 5.8e-05 22.8 2.3 0.0018 18.0 0.2 2.0 1 1 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 CBK21040.2 - 0.035 13.5 0.3 0.093 12.1 0.3 1.7 1 1 0 1 1 1 0 Sulfatase CBM_48 PF02922.18 CBK21041.2 - 5.9e-05 23.3 0.0 0.00021 21.6 0.0 1.9 2 0 0 2 2 2 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) Alpha-amylase PF00128.24 CBK21041.2 - 0.00048 19.8 0.0 0.0038 16.9 0.0 2.3 3 0 0 3 3 3 1 Alpha amylase, catalytic domain Y_phosphatase PF00102.27 CBK21042.2 - 2.9e-06 27.0 0.0 3.3e-06 26.8 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 CBK21042.2 - 3.6e-05 23.9 0.0 3.9e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 Tyrosine phosphatase family CDKN3 PF05706.12 CBK21042.2 - 0.00039 20.1 0.0 0.00092 18.9 0.0 1.7 1 1 0 1 1 1 1 Cyclin-dependent kinase inhibitor 3 (CDKN3) PTPlike_phytase PF14566.6 CBK21042.2 - 0.00049 20.2 0.0 0.001 19.2 0.0 1.5 1 1 1 2 2 2 1 Inositol hexakisphosphate DSPc PF00782.20 CBK21042.2 - 0.0045 16.8 0.0 0.0053 16.6 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase2 PF03162.13 CBK21042.2 - 0.023 14.3 0.9 0.044 13.4 0.9 1.7 1 1 0 1 1 1 0 Tyrosine phosphatase family Ribosomal_L29 PF00831.23 CBK21044.2 - 1.3e-17 63.5 1.0 1.3e-17 63.5 1.0 2.4 1 1 1 2 2 2 1 Ribosomal L29 protein Rogdi_lz PF10259.9 CBK21044.2 - 0.011 15.2 0.4 0.013 14.9 0.4 1.1 1 0 0 1 1 1 0 Rogdi leucine zipper containing protein Ribosomal_S9 PF00380.19 CBK21044.2 - 0.031 14.8 7.0 0.048 14.2 7.0 1.4 1 1 0 1 1 1 0 Ribosomal protein S9/S16 tRNA-synt_1c PF00749.21 CBK21046.2 - 6.2e-109 363.7 0.0 8.2e-109 363.3 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.18 CBK21046.2 - 1.2e-36 126.2 0.0 2.1e-36 125.4 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain DUF4698 PF15769.5 CBK21046.2 - 0.042 12.9 0.2 0.79 8.7 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4698) tRNA_synt_1c_R1 PF04558.15 CBK21047.2 - 1.9e-26 93.0 0.0 2.4e-26 92.7 0.0 1.2 1 0 0 1 1 1 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 Glycos_trans_3N PF02885.17 CBK21047.2 - 0.17 11.8 0.0 0.32 10.9 0.0 1.5 1 0 0 1 1 1 0 Glycosyl transferase family, helical bundle domain ArfGap PF01412.18 CBK21048.2 - 1.2e-37 128.6 7.6 7.1e-37 126.1 7.6 2.1 1 1 0 1 1 1 1 Putative GTPase activating protein for Arf PMM PF03332.13 CBK21049.2 - 3.4e-74 249.3 0.6 4.1e-74 249.1 0.6 1.0 1 0 0 1 1 1 1 Eukaryotic phosphomannomutase Corona_nucleoca PF00937.18 CBK21050.2 - 3.1 6.8 9.7 4.9 6.1 9.7 1.2 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein ERM PF00769.19 CBK21051.2 - 0.36 10.6 37.5 0.017 15.0 21.0 2.1 1 1 0 2 2 2 0 Ezrin/radixin/moesin family MALT1_Ig PF18703.1 CBK21051.2 - 2.3 8.2 8.8 0.24 11.4 0.6 2.6 1 1 1 2 2 2 0 MALT1 Ig-like domain BBS1 PF14779.6 CBK21051.2 - 2.9 7.2 16.8 0.026 14.0 7.6 1.9 1 1 1 2 2 2 0 Ciliary BBSome complex subunit 1 CENP-F_leu_zip PF10473.9 CBK21051.2 - 6.5 6.8 40.9 3.8 7.5 20.9 3.2 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 AhpC-TSA PF00578.21 CBK21053.2 - 8.4e-36 122.6 0.0 1.1e-35 122.3 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family 1-cysPrx_C PF10417.9 CBK21053.2 - 1e-11 44.5 0.0 2.2e-11 43.4 0.0 1.5 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin Redoxin PF08534.10 CBK21053.2 - 1.2e-11 44.6 0.0 1.5e-11 44.2 0.0 1.1 1 0 0 1 1 1 1 Redoxin Kinesin PF00225.23 CBK21054.2 - 8.9e-28 97.2 0.0 1.5e-27 96.4 0.0 1.3 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 CBK21054.2 - 1.7e-11 44.3 0.0 3.4e-11 43.3 0.0 1.5 1 0 0 1 1 1 1 Microtubule binding zinc_ribbon_4 PF13717.6 CBK21054.2 - 0.074 13.0 0.2 0.17 11.8 0.2 1.5 1 0 0 1 1 1 0 zinc-ribbon domain Angiomotin_C PF12240.8 CBK21054.2 - 0.56 9.7 3.9 0.98 8.9 3.9 1.3 1 0 0 1 1 1 0 Angiomotin C terminal WD40 PF00400.32 CBK21055.2 - 1.9e-06 28.5 2.6 0.13 13.2 0.2 5.1 5 0 0 5 5 5 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBK21055.2 - 5.3e-05 23.4 0.0 5.5 7.4 0.0 4.9 3 2 0 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain E2F_TDP PF02319.20 CBK21056.2 - 2.4e-17 62.7 0.5 1.5e-09 37.8 0.1 2.4 2 1 0 2 2 2 2 E2F/DP family winged-helix DNA-binding domain WD40 PF00400.32 CBK21057.2 - 2.5e-10 40.8 1.0 0.0046 17.8 0.0 4.1 4 0 0 4 4 4 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBK21057.2 - 1e-05 25.7 0.0 3 8.2 0.0 3.5 2 1 0 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain YfmQ PF10787.9 CBK21057.2 - 0.026 14.3 0.1 0.042 13.6 0.1 1.3 1 0 0 1 1 1 0 Uncharacterised protein from bacillus cereus group Ge1_WD40 PF16529.5 CBK21057.2 - 0.056 12.4 0.1 0.1 11.5 0.1 1.4 1 0 0 1 1 1 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Pkinase PF00069.25 CBK21058.2 - 2.3e-33 115.7 0.0 2.7e-33 115.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBK21058.2 - 2.6e-30 105.6 0.0 3.1e-30 105.3 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Choline_kinase PF01633.20 CBK21058.2 - 0.026 14.1 0.1 0.042 13.4 0.1 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase Tox-SHH PF15652.6 CBK21058.2 - 0.087 13.8 0.0 0.17 12.8 0.0 1.5 1 0 0 1 1 1 0 HNH/Endo VII superfamily toxin with a SHH signature RNA_pol_Rpb6 PF01192.22 CBK21059.2 - 2.7e-16 59.2 0.1 3.3e-16 58.9 0.1 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb6 zf-C2H2 PF00096.26 CBK21060.2 - 4.2e-10 39.5 14.5 0.0012 19.1 0.6 3.9 4 0 0 4 4 3 3 Zinc finger, C2H2 type HMG_box PF00505.19 CBK21060.2 - 8.5e-08 32.5 0.4 8.5e-08 32.5 0.4 2.9 2 1 1 3 3 3 1 HMG (high mobility group) box HMG_box_2 PF09011.10 CBK21060.2 - 1.2e-05 25.7 0.3 1.2e-05 25.7 0.3 2.9 2 1 1 3 3 3 1 HMG-box domain zf-C2H2_4 PF13894.6 CBK21060.2 - 2e-05 25.0 12.9 0.047 14.5 0.6 4.1 3 1 0 3 3 3 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 CBK21060.2 - 7.3e-05 23.0 18.0 0.00022 21.5 0.2 4.6 5 0 0 5 5 4 2 Zinc-finger double domain zf-C2H2_aberr PF17017.5 CBK21060.2 - 0.00086 19.5 6.6 0.02 15.1 1.9 2.4 1 1 1 2 2 2 2 Aberrant zinc-finger CpXC PF14353.6 CBK21060.2 - 0.025 14.6 4.7 0.75 9.8 0.1 2.8 1 1 1 2 2 2 0 CpXC protein FapA PF03961.13 CBK21060.2 - 0.025 13.2 1.7 0.033 12.8 1.7 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A zf-C2H2_jaz PF12171.8 CBK21060.2 - 0.028 14.7 2.3 0.61 10.5 0.2 3.1 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 CBK21060.2 - 0.039 13.9 0.3 0.039 13.9 0.3 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger zf_UBZ PF18439.1 CBK21060.2 - 0.061 12.9 1.1 0.47 10.1 0.0 2.8 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger zf-RRN7 PF11781.8 CBK21060.2 - 0.087 12.5 1.1 1.2 8.9 0.1 2.4 2 0 0 2 2 2 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 zinc_ribbon_12 PF11331.8 CBK21060.2 - 0.2 11.5 1.7 1 9.2 0.0 2.8 3 0 0 3 3 3 0 Probable zinc-ribbon domain Zn-ribbon_8 PF09723.10 CBK21060.2 - 0.77 9.9 5.7 1 9.5 1.9 2.7 2 1 1 3 3 3 0 Zinc ribbon domain zf-AN1 PF01428.16 CBK21060.2 - 1.7 8.9 7.7 0.39 10.9 0.7 2.8 3 0 0 3 3 3 0 AN1-like Zinc finger HSP70 PF00012.20 CBK21061.2 - 9.4e-127 423.7 0.1 1.4e-126 423.2 0.1 1.2 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 CBK21061.2 - 3.3e-17 62.3 0.4 1.8e-15 56.6 0.1 2.2 2 0 0 2 2 2 2 MreB/Mbl protein Mononeg_mRNAcap PF14318.6 CBK21061.2 - 0.036 13.3 0.0 0.062 12.6 0.0 1.3 1 0 0 1 1 1 0 Mononegavirales mRNA-capping region V DUF2949 PF11165.8 CBK21061.2 - 0.072 13.4 0.8 0.21 11.9 0.8 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2949) DUF5082 PF16888.5 CBK21061.2 - 0.081 13.2 3.4 0.18 12.1 3.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5082) DDR PF08841.10 CBK21061.2 - 0.13 11.2 0.1 0.33 9.9 0.1 1.6 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain Methyltransf_25 PF13649.6 CBK21063.2 - 3.8e-05 24.3 0.0 4.3e-05 24.2 0.0 1.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CBK21063.2 - 0.00027 20.7 0.0 0.00031 20.5 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CBK21063.2 - 0.00056 20.5 0.0 0.00063 20.3 0.0 1.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CBK21063.2 - 0.037 14.8 0.0 0.04 14.7 0.0 1.1 1 0 0 1 1 1 0 Methyltransferase domain Ribosomal_S6e PF01092.19 CBK21064.2 - 1e-56 190.3 0.0 1e-56 190.3 0.0 1.5 2 0 0 2 2 2 1 Ribosomal protein S6e Galactosyl_T PF01762.21 CBK21065.2 - 7e-30 104.3 0.1 3.3e-29 102.1 0.0 2.0 2 0 0 2 2 2 1 Galactosyltransferase Dus PF01207.17 CBK21066.2 - 3.1e-55 187.4 0.0 3.5e-55 187.3 0.0 1.0 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) His_biosynth PF00977.21 CBK21066.2 - 6.4e-08 32.3 0.0 1.1e-06 28.3 0.0 2.3 1 1 2 3 3 3 1 Histidine biosynthesis protein TMP-TENI PF02581.17 CBK21066.2 - 0.00058 19.2 0.0 0.00091 18.6 0.0 1.3 1 0 0 1 1 1 1 Thiamine monophosphate synthase ThiG PF05690.14 CBK21066.2 - 0.00071 19.0 0.0 0.0011 18.4 0.0 1.3 1 0 0 1 1 1 1 Thiazole biosynthesis protein ThiG DUF561 PF04481.12 CBK21066.2 - 0.0027 16.9 0.0 0.004 16.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF561) NMO PF03060.15 CBK21066.2 - 0.011 15.2 0.0 0.015 14.7 0.0 1.2 1 0 0 1 1 1 0 Nitronate monooxygenase NanE PF04131.14 CBK21066.2 - 0.011 14.9 0.0 0.017 14.3 0.0 1.2 1 0 0 1 1 1 0 Putative N-acetylmannosamine-6-phosphate epimerase FMN_dh PF01070.18 CBK21066.2 - 0.016 14.2 0.0 0.02 13.9 0.0 1.1 1 0 0 1 1 1 0 FMN-dependent dehydrogenase IMPDH PF00478.25 CBK21066.2 - 0.04 12.9 0.0 0.061 12.3 0.0 1.2 1 0 0 1 1 1 0 IMP dehydrogenase / GMP reductase domain G3P_antiterm PF04309.12 CBK21066.2 - 0.077 12.4 0.0 0.14 11.6 0.0 1.4 1 0 0 1 1 1 0 Glycerol-3-phosphate responsive antiterminator IGPS PF00218.21 CBK21066.2 - 0.18 10.9 0.0 0.24 10.5 0.0 1.3 1 0 0 1 1 1 0 Indole-3-glycerol phosphate synthase Ribosomal_S3Ae PF01015.18 CBK21067.2 - 2.6e-84 281.8 2.9 3.5e-84 281.4 2.9 1.1 1 0 0 1 1 1 1 Ribosomal S3Ae family SUI1 PF01253.22 CBK21067.2 - 0.0016 18.9 0.4 0.0067 16.9 0.3 2.2 1 1 1 2 2 2 1 Translation initiation factor SUI1 Abhydro_lipase PF04083.16 CBK21067.2 - 0.026 14.1 0.1 0.078 12.6 0.0 1.8 2 0 0 2 2 2 0 Partial alpha/beta-hydrolase lipase region DUF3395 PF11875.8 CBK21067.2 - 0.033 14.1 0.0 0.11 12.3 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3395) Chitin_bind_1 PF00187.19 CBK21067.2 - 2 8.9 7.6 0.23 12.0 3.2 1.8 2 0 0 2 2 2 0 Chitin recognition protein NIF PF03031.18 CBK21068.2 - 2.1e-20 73.1 0.3 2.6e-20 72.8 0.3 1.1 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase ENTH PF01417.20 CBK21070.2 - 7.8e-32 109.9 0.1 1.4e-31 109.1 0.1 1.4 1 0 0 1 1 1 1 ENTH domain ANTH PF07651.16 CBK21070.2 - 0.0027 16.8 0.0 0.0056 15.7 0.0 1.5 1 0 0 1 1 1 1 ANTH domain AMP-binding PF00501.28 CBK21071.2 - 5.4e-82 275.6 0.0 7.1e-82 275.3 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme RhoGEF PF00621.20 CBK21072.2 - 9.6e-47 159.6 0.5 1.2e-46 159.2 0.5 1.1 1 0 0 1 1 1 1 RhoGEF domain Sec63 PF02889.16 CBK21073.2 - 3.2e-131 436.1 0.1 7.9e-80 267.7 0.1 2.3 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.29 CBK21073.2 - 2.8e-42 144.5 0.5 7e-24 84.5 0.1 3.4 3 0 0 3 3 3 2 DEAD/DEAH box helicase Helicase_PWI PF18149.1 CBK21073.2 - 5.9e-31 106.9 1.9 1.5e-30 105.6 0.3 2.4 2 0 0 2 2 2 1 N-terminal helicase PWI domain ResIII PF04851.15 CBK21073.2 - 2.5e-19 69.9 0.0 1.8e-11 44.4 0.0 2.8 3 0 0 3 3 3 2 Type III restriction enzyme, res subunit Helicase_C PF00271.31 CBK21073.2 - 7.2e-10 39.2 0.0 4.8e-07 30.1 0.0 3.9 3 2 0 3 3 3 1 Helicase conserved C-terminal domain AAA_19 PF13245.6 CBK21073.2 - 0.0029 17.9 0.5 0.25 11.7 0.0 3.3 3 0 0 3 3 3 1 AAA domain AAA_22 PF13401.6 CBK21073.2 - 0.012 15.9 0.1 0.18 12.1 0.0 3.0 2 1 0 2 2 2 0 AAA domain E1-E2_ATPase PF00122.20 CBK21074.2 - 4.1e-53 179.6 0.8 1.6e-51 174.4 0.0 2.7 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 CBK21074.2 - 1.4e-49 168.3 0.7 3.3e-49 167.0 0.7 1.7 1 0 0 1 1 1 1 Cation transporting ATPase, C-terminus Cation_ATPase PF13246.6 CBK21074.2 - 5.6e-22 77.6 0.0 9.8e-22 76.9 0.0 1.4 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 CBK21074.2 - 1.3e-19 69.6 0.8 3.9e-19 68.1 0.0 2.2 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase PF00702.26 CBK21074.2 - 2.9e-19 70.2 2.8 8.4e-19 68.7 0.8 2.8 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 CBK21074.2 - 3.4e-05 23.7 0.4 0.00046 20.0 0.4 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 CBK21074.2 - 0.023 15.1 0.0 0.056 13.8 0.0 1.7 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase RrnaAD PF00398.20 CBK21075.2 - 5.9e-59 199.3 0.0 7.2e-59 199.0 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_25 PF13649.6 CBK21075.2 - 1.7e-07 31.9 0.0 5.6e-07 30.2 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain PCMT PF01135.19 CBK21075.2 - 2.4e-05 24.2 0.1 4.1e-05 23.4 0.1 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_11 PF08241.12 CBK21075.2 - 6e-05 23.6 0.0 0.00019 22.0 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Cons_hypoth95 PF03602.15 CBK21075.2 - 0.00017 21.3 0.0 0.00061 19.5 0.0 1.8 2 0 0 2 2 2 1 Conserved hypothetical protein 95 MTS PF05175.14 CBK21075.2 - 0.00039 20.0 0.0 0.00072 19.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_15 PF09445.10 CBK21075.2 - 0.00039 20.0 0.0 0.033 13.8 0.0 2.2 2 0 0 2 2 2 1 RNA cap guanine-N2 methyltransferase UPF0020 PF01170.18 CBK21075.2 - 0.00068 19.4 0.0 0.0014 18.4 0.0 1.5 2 0 0 2 2 2 1 Putative RNA methylase family UPF0020 PRMT5 PF05185.16 CBK21075.2 - 0.00078 19.3 0.3 0.0027 17.6 0.0 1.9 2 0 0 2 2 2 1 PRMT5 arginine-N-methyltransferase Methyltransf_12 PF08242.12 CBK21075.2 - 0.0026 18.5 0.0 0.0078 16.9 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.7 CBK21075.2 - 0.0027 17.6 0.0 0.0058 16.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 CBK21075.2 - 0.0059 16.0 0.0 0.0088 15.5 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_4 PF02390.17 CBK21075.2 - 0.0069 15.9 0.0 0.014 14.9 0.0 1.5 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_23 PF13489.6 CBK21075.2 - 0.0092 15.8 0.0 0.015 15.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 CBK21075.2 - 0.01 15.2 0.0 0.02 14.2 0.0 1.4 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Met_10 PF02475.16 CBK21075.2 - 0.028 14.2 0.1 0.2 11.4 0.1 1.9 2 0 0 2 2 2 0 Met-10+ like-protein NodS PF05401.11 CBK21075.2 - 0.12 12.0 0.0 0.22 11.1 0.0 1.4 1 0 0 1 1 1 0 Nodulation protein S (NodS) Methyltransf_2 PF00891.18 CBK21075.2 - 0.13 11.5 0.0 0.22 10.8 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase domain Acetyltransf_1 PF00583.25 CBK21076.2 - 0.0044 17.2 0.0 0.0078 16.4 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family DUF1451 PF07295.11 CBK21076.2 - 0.33 11.0 2.4 0.61 10.1 2.4 1.4 1 0 0 1 1 1 0 Zinc-ribbon containing domain UPF0242 PF06785.11 CBK21076.2 - 0.96 9.5 6.3 1.4 9.0 5.7 1.6 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus HSP70 PF00012.20 CBK21077.2 - 9.3e-74 248.7 0.0 1.2e-73 248.4 0.0 1.0 1 0 0 1 1 1 1 Hsp70 protein StbA PF06406.11 CBK21077.2 - 0.0023 17.2 0.3 0.043 13.0 0.1 2.2 1 1 1 2 2 2 1 StbA protein PHC2_SAM_assoc PF16616.5 CBK21077.2 - 0.1 13.4 0.1 0.22 12.3 0.1 1.5 1 0 0 1 1 1 0 Unstructured region on Polyhomeotic-like protein 1 and 2 HAT PF02184.16 CBK21078.2 - 1.3e-10 41.0 7.9 7e-07 29.1 0.7 3.5 3 0 0 3 3 3 3 HAT (Half-A-TPR) repeat TPR_14 PF13428.6 CBK21078.2 - 5.2e-05 23.7 0.1 0.037 14.8 0.0 2.7 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 CBK21078.2 - 0.0016 18.4 0.0 1.7 8.9 0.0 2.8 3 0 0 3 3 3 2 Tetratricopeptide repeat U3_assoc_6 PF08640.11 CBK21078.2 - 0.012 15.7 4.5 0.081 13.0 1.6 2.4 1 1 1 2 2 2 0 U3 small nucleolar RNA-associated protein 6 TPR_19 PF14559.6 CBK21078.2 - 0.013 16.0 0.0 0.023 15.2 0.0 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat Suf PF05843.14 CBK21078.2 - 0.016 15.2 0.8 0.016 15.2 0.8 1.6 1 1 1 2 2 2 0 Suppressor of forked protein (Suf) Mad3_BUB1_I PF08311.12 CBK21078.2 - 0.031 14.3 1.4 8.4 6.4 0.3 2.4 2 1 0 2 2 2 0 Mad3/BUB1 homology region 1 TPR_17 PF13431.6 CBK21078.2 - 0.052 13.9 0.0 0.1 13.0 0.0 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_8 PF13181.6 CBK21078.2 - 0.12 12.6 0.0 7.6 7.0 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat HSP70 PF00012.20 CBK21079.2 - 6e-84 282.3 0.0 7.4e-84 282.0 0.0 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 CBK21079.2 - 1.7e-15 56.7 0.3 1.7e-13 50.1 0.1 2.4 2 1 0 2 2 2 2 MreB/Mbl protein HSP70 PF00012.20 CBK21080.2 - 1.1e-64 218.7 0.1 1.4e-64 218.4 0.1 1.1 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 CBK21080.2 - 1.2e-14 53.9 0.0 4.4e-13 48.7 0.0 2.1 2 0 0 2 2 2 2 MreB/Mbl protein StbA PF06406.11 CBK21080.2 - 0.00063 19.1 0.7 0.015 14.6 0.7 2.2 1 1 0 1 1 1 1 StbA protein DDR PF08841.10 CBK21080.2 - 0.017 14.1 0.1 4.8 6.1 0.1 2.2 2 0 0 2 2 2 0 Diol dehydratase reactivase ATPase-like domain Pyrophosphatase PF00719.19 CBK21081.2 - 1.3e-35 122.5 0.1 1.7e-35 122.2 0.1 1.1 1 0 0 1 1 1 1 Inorganic pyrophosphatase Lung_7-TM_R PF06814.13 CBK21082.2 - 1.4e-25 90.2 7.4 6.5e-25 88.0 7.6 1.8 2 0 0 2 2 2 1 Lung seven transmembrane receptor GpcrRhopsn4 PF10192.9 CBK21082.2 - 0.00017 21.1 7.2 0.00017 21.1 7.2 1.5 2 0 0 2 2 2 1 Rhodopsin-like GPCR transmembrane domain zf-RING_2 PF13639.6 CBK21083.2 - 8.7e-13 48.4 9.5 8.7e-13 48.4 9.5 2.2 2 0 0 2 2 2 1 Ring finger domain zinc_ribbon_9 PF14369.6 CBK21083.2 - 3.4e-09 36.8 12.5 5.8e-07 29.7 3.8 3.4 3 0 0 3 3 3 2 zinc-ribbon zf-RING_11 PF17123.5 CBK21083.2 - 6.3e-09 35.4 3.6 1.5e-08 34.2 3.6 1.7 1 0 0 1 1 1 1 RING-like zinc finger zf-rbx1 PF12678.7 CBK21083.2 - 9e-08 32.3 9.9 9e-08 32.3 9.9 2.4 2 1 1 3 3 3 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 CBK21083.2 - 1.6e-07 31.1 8.9 1.6e-07 31.1 8.9 2.7 2 2 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CBK21083.2 - 1.4e-06 28.0 9.3 1.4e-06 28.0 9.3 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CBK21083.2 - 1.6e-05 24.7 5.4 1.6e-05 24.7 5.4 2.4 2 0 0 2 2 2 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 CBK21083.2 - 4.8e-05 23.3 2.0 4.8e-05 23.3 2.0 1.7 2 0 0 2 2 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.6 CBK21083.2 - 5.2e-05 23.2 6.6 5.2e-05 23.2 6.6 2.4 2 1 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 CBK21083.2 - 0.0001 22.1 6.8 0.0001 22.1 6.8 2.8 2 2 1 3 3 3 2 Zinc finger, C3HC4 type (RING finger) DZR PF12773.7 CBK21083.2 - 0.00066 19.6 12.8 0.058 13.4 1.9 3.0 2 1 0 2 2 2 2 Double zinc ribbon Zn_ribbon_17 PF17120.5 CBK21083.2 - 0.00071 19.1 3.0 0.00071 19.1 3.0 2.2 2 1 0 2 2 2 1 Zinc-ribbon, C4HC2 type Prok-RING_4 PF14447.6 CBK21083.2 - 0.0016 18.3 4.9 0.0016 18.3 4.9 3.0 2 2 1 3 3 2 2 Prokaryotic RING finger family 4 TerY_C PF15616.6 CBK21083.2 - 0.0029 17.7 0.8 0.0029 17.7 0.8 2.1 2 0 0 2 2 2 1 TerY-C metal binding domain zf_UBZ PF18439.1 CBK21083.2 - 0.0085 15.7 13.0 1.1 8.9 0.3 4.1 4 0 0 4 4 4 1 Ubiquitin-Binding Zinc Finger zinc-ribbons_6 PF07191.12 CBK21083.2 - 0.0097 15.9 11.4 0.28 11.2 1.8 2.5 2 1 0 2 2 2 2 zinc-ribbons HypA PF01155.19 CBK21083.2 - 0.01 15.8 7.9 0.039 14.0 0.9 2.4 2 1 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Vps39_2 PF10367.9 CBK21083.2 - 0.029 14.8 0.6 0.029 14.8 0.6 3.6 4 0 0 4 4 4 0 Vacuolar sorting protein 39 domain 2 Rad50_zn_hook PF04423.14 CBK21083.2 - 0.032 14.1 1.4 2.2 8.2 0.1 2.3 2 0 0 2 2 2 0 Rad50 zinc hook motif Prok-RING_1 PF14446.6 CBK21083.2 - 0.067 13.1 1.1 0.067 13.1 1.1 3.3 3 1 1 4 4 4 0 Prokaryotic RING finger family 1 PHD PF00628.29 CBK21083.2 - 0.083 12.8 19.7 0.13 12.1 5.6 3.2 2 1 1 3 3 3 0 PHD-finger YdjO PF14169.6 CBK21083.2 - 0.11 12.2 6.4 0.45 10.3 0.0 3.2 4 0 0 4 4 4 0 Cold-inducible protein YdjO zf-C3HC4_4 PF15227.6 CBK21083.2 - 0.24 11.6 17.2 0.37 11.0 6.7 2.6 2 1 0 2 2 2 0 zinc finger of C3HC4-type, RING TackOD1 PF18551.1 CBK21083.2 - 0.27 10.9 9.2 1.4 8.6 1.2 2.3 2 0 0 2 2 2 0 Thaumarchaeal output domain 1 Sgf11 PF08209.11 CBK21083.2 - 0.5 10.0 0.1 0.5 10.0 0.1 3.3 4 0 0 4 4 3 0 Sgf11 (transcriptional regulation protein) UPF0547 PF10571.9 CBK21083.2 - 0.55 10.4 0.2 0.55 10.4 0.2 3.4 4 0 0 4 4 3 0 Uncharacterised protein family UPF0547 Zn-ribbon_8 PF09723.10 CBK21083.2 - 0.94 9.7 18.8 14 5.9 0.8 3.9 3 1 1 4 4 4 0 Zinc ribbon domain zf-H2C2_2 PF13465.6 CBK21083.2 - 0.94 10.0 0.1 0.94 10.0 0.1 4.1 4 0 0 4 4 4 0 Zinc-finger double domain Zn_Tnp_IS1595 PF12760.7 CBK21083.2 - 2.8 8.0 14.5 29 4.7 0.0 3.6 3 1 0 3 3 3 0 Transposase zinc-ribbon domain FANCL_C PF11793.8 CBK21083.2 - 3.9 7.7 9.5 16 5.7 6.5 3.2 2 1 0 2 2 2 0 FANCL C-terminal domain DUF1272 PF06906.11 CBK21083.2 - 4.5 7.5 14.0 0.53 10.4 3.8 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1272) Ribosomal_L27A PF00828.19 CBK21084.2 - 5.6e-17 62.6 0.0 7.5e-17 62.2 0.0 1.1 1 0 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A Slx4 PF09494.10 CBK21084.2 - 0.013 15.5 0.0 0.023 14.7 0.0 1.5 1 0 0 1 1 1 0 Slx4 endonuclease MORN PF02493.20 CBK21084.2 - 0.091 12.7 0.0 0.22 11.5 0.0 1.7 1 0 0 1 1 1 0 MORN repeat Porin_3 PF01459.22 CBK21087.2 - 0.016 14.7 0.0 0.017 14.6 0.0 1.0 1 0 0 1 1 1 0 Eukaryotic porin PT PF04886.12 CBK21088.2 - 0.00022 20.7 8.1 0.00022 20.7 8.1 8.2 5 2 1 6 6 6 2 PT repeat LAP1C PF05609.12 CBK21088.2 - 2.2 7.3 14.6 2.8 7.0 14.6 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) NDUFB10 PF10249.9 CBK21089.2 - 6.1e-05 23.5 0.2 7.1e-05 23.3 0.2 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase subunit 10 COX17 PF05051.13 CBK21089.2 - 0.0018 18.6 0.1 0.0034 17.7 0.1 1.4 1 0 0 1 1 1 1 Cytochrome C oxidase copper chaperone (COX17) GDA1_CD39 PF01150.17 CBK21090.2 - 2.4e-09 36.4 0.0 3.2e-09 36.0 0.0 1.1 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family GDA1_CD39 PF01150.17 CBK21091.2 - 2e-36 125.6 0.0 6.8e-36 123.8 0.0 1.7 1 1 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family OxoDH_E1alpha_N PF12573.8 CBK21091.2 - 0.14 11.9 0.6 4 7.3 0.1 2.4 2 0 0 2 2 2 0 2-oxoisovalerate dehydrogenase E1 alpha subunit N terminal EMG1 PF03587.14 CBK21092.2 - 7.3e-56 188.9 0.0 8e-56 188.8 0.0 1.0 1 0 0 1 1 1 1 EMG1/NEP1 methyltransferase TBCC PF07986.12 CBK21092.2 - 0.1 12.3 0.0 0.17 11.6 0.0 1.3 1 0 0 1 1 1 0 Tubulin binding cofactor C PHF5 PF03660.14 CBK21093.2 - 8.9e-46 154.4 14.7 1e-45 154.2 14.7 1.0 1 0 0 1 1 1 1 PHF5-like protein PolC_DP2 PF03833.13 CBK21093.2 - 2 6.1 9.0 2.1 6.1 9.0 1.1 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 C1_2 PF03107.16 CBK21093.2 - 3 8.2 20.7 0.12 12.8 2.6 2.7 1 1 1 2 2 2 0 C1 domain DZR PF12773.7 CBK21093.2 - 4 7.5 16.7 0.28 11.3 1.0 3.0 2 1 0 2 2 2 0 Double zinc ribbon Adaptin_N PF01602.20 CBK21094.2 - 6.4e-120 401.2 8.9 7.9e-120 400.9 8.9 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 CBK21094.2 - 4e-57 192.8 2.4 3.3e-56 189.8 0.2 2.8 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 CBK21094.2 - 3.9e-08 32.9 10.7 0.0059 16.8 0.1 5.8 6 1 1 7 7 7 3 HEAT repeat HEAT_2 PF13646.6 CBK21094.2 - 8.7e-06 26.0 9.1 0.0008 19.8 0.0 4.8 3 1 2 5 5 5 1 HEAT repeats CLASP_N PF12348.8 CBK21094.2 - 7.5e-05 22.4 0.8 0.00058 19.5 0.0 2.9 4 0 0 4 4 4 1 CLASP N terminal HEAT_EZ PF13513.6 CBK21094.2 - 0.026 15.0 3.6 1.8 9.1 0.2 5.2 5 1 0 5 5 5 0 HEAT-like repeat RTP1_C1 PF10363.9 CBK21094.2 - 0.078 13.2 3.8 3.7 7.8 0.0 4.3 2 1 2 4 4 4 0 Required for nuclear transport of RNA pol II C-terminus 1 TIP120 PF08623.10 CBK21094.2 - 2 8.2 6.5 11 5.7 0.1 3.9 5 0 0 5 5 5 0 TATA-binding protein interacting (TIP20) SMC_N PF02463.19 CBK21095.2 - 1.5e-59 201.1 0.0 1.8e-58 197.6 0.0 2.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 CBK21095.2 - 1.8e-20 73.4 3.2 3.6e-20 72.4 0.1 3.3 4 0 0 4 4 4 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 CBK21095.2 - 1.9e-11 44.4 1.3 1.8e-07 31.3 0.0 3.4 2 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SbcCD_C PF13558.6 CBK21095.2 - 0.00047 20.3 0.0 0.0035 17.5 0.0 2.6 2 0 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_15 PF13175.6 CBK21095.2 - 0.0043 16.8 5.8 0.019 14.7 5.3 2.3 1 1 0 1 1 1 1 AAA ATPase domain Pox_F11 PF04943.12 CBK21095.2 - 0.014 14.5 0.2 0.014 14.5 0.2 2.5 2 0 0 2 2 2 0 Poxvirus F11 protein DUF2149 PF09919.9 CBK21095.2 - 0.075 13.3 2.7 0.13 12.6 0.0 2.8 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2149) AAA_29 PF13555.6 CBK21095.2 - 0.078 12.7 0.0 0.67 9.7 0.0 2.3 1 1 0 1 1 1 0 P-loop containing region of AAA domain Crust_neuro_H PF03858.13 CBK21095.2 - 0.56 11.1 4.5 1 10.2 0.3 3.2 2 0 0 2 2 2 0 Crustacean neurohormone H tRNA-synt_2b PF00587.25 CBK21096.2 - 1.5e-38 132.6 0.0 2.5e-38 131.8 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 CBK21096.2 - 1.1e-20 73.6 0.2 2e-20 72.7 0.2 1.5 1 0 0 1 1 1 1 Anticodon binding domain tRNA_SAD PF07973.14 CBK21096.2 - 1.1e-10 41.4 0.0 6.7e-10 38.9 0.0 2.3 2 0 0 2 2 2 1 Threonyl and Alanyl tRNA synthetase second additional domain TGS PF02824.21 CBK21096.2 - 4.5e-09 36.2 0.0 1.8e-06 27.9 0.0 3.0 2 1 0 2 2 2 2 TGS domain YscW PF09619.10 CBK21096.2 - 0.05 13.9 0.0 0.11 12.8 0.0 1.5 1 0 0 1 1 1 0 Type III secretion system lipoprotein chaperone (YscW) He_PIG PF05345.12 CBK21097.2 - 9e-09 35.4 14.3 2.6e-06 27.5 1.9 3.3 3 0 0 3 3 3 2 Putative Ig domain F5_F8_type_C PF00754.25 CBK21097.2 - 0.0011 19.0 0.6 0.0064 16.6 0.3 2.4 2 0 0 2 2 2 1 F5/8 type C domain DUF11 PF01345.18 CBK21097.2 - 0.1 12.9 1.2 3.5 8.0 0.3 3.3 2 1 0 2 2 2 0 Domain of unknown function DUF11 Cadherin_C_2 PF16492.5 CBK21097.2 - 0.12 13.2 0.1 0.47 11.2 0.0 2.1 2 0 0 2 2 2 0 Cadherin cytoplasmic C-terminal Laminin_G_3 PF13385.6 CBK21097.2 - 0.15 12.2 6.4 0.6 10.3 0.3 3.5 3 0 0 3 3 3 0 Concanavalin A-like lectin/glucanases superfamily DUF5385 PF17359.2 CBK21097.2 - 0.38 10.3 1.0 0.59 9.6 1.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5385) Collectrin PF16959.5 CBK21097.2 - 0.45 10.3 4.7 0.96 9.2 4.7 1.5 1 0 0 1 1 1 0 Renal amino acid transporter DUF3094 PF11293.8 CBK21097.2 - 7.7 6.3 5.9 4.9 7.0 3.4 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3094) RNA_pol_Rpb2_6 PF00562.28 CBK21098.2 - 4.9e-111 371.6 0.0 1.2e-110 370.2 0.0 1.6 1 1 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 CBK21098.2 - 4.8e-33 114.4 0.0 7.2e-33 113.8 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_3 PF04565.16 CBK21098.2 - 1.6e-27 95.5 0.0 3.1e-27 94.6 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_7 PF04560.20 CBK21098.2 - 6.1e-23 81.0 0.1 1.5e-22 79.7 0.1 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_2 PF04561.14 CBK21098.2 - 1e-22 80.7 0.1 1.6e-22 80.1 0.1 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpa2_4 PF06883.12 CBK21098.2 - 1.1e-14 54.1 0.0 2.9e-14 52.8 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase I, Rpa2 specific domain RNA_pol_Rpb2_4 PF04566.13 CBK21098.2 - 0.021 15.1 0.0 0.048 14.0 0.0 1.7 1 0 0 1 1 1 0 RNA polymerase Rpb2, domain 4 Ribosomal_S11 PF00411.19 CBK21099.2 - 8.2e-47 158.2 1.2 1e-46 157.8 1.2 1.1 1 0 0 1 1 1 1 Ribosomal protein S11 CBM_25 PF03423.13 CBK21099.2 - 0.014 15.6 0.1 0.042 14.1 0.1 1.7 2 0 0 2 2 2 0 Carbohydrate binding domain (family 25) DUF2252 PF10009.9 CBK21099.2 - 0.047 12.7 0.0 0.056 12.5 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2252) Condensin2nSMC PF12422.8 CBK21100.2 - 5.1e-18 65.7 1.5 7.6e-17 61.9 0.1 2.5 3 0 0 3 3 3 1 Condensin II non structural maintenance of chromosomes subunit Cnd1 PF12717.7 CBK21100.2 - 2.2e-06 27.8 1.7 0.0012 18.9 0.2 3.0 1 1 2 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 CBK21100.2 - 3e-06 27.0 1.0 0.67 10.4 0.0 4.3 4 0 0 4 4 4 2 HEAT repeat Adaptin_N PF01602.20 CBK21100.2 - 0.0081 14.8 0.3 0.07 11.7 0.0 2.0 1 1 1 2 2 2 1 Adaptin N terminal region Toxin_4 PF00706.17 CBK21100.2 - 0.053 14.0 0.0 0.091 13.2 0.0 1.3 1 0 0 1 1 1 0 Anenome neurotoxin RNA_pol_A_bac PF01000.26 CBK21101.2 - 3.9e-25 88.4 0.5 1.8e-24 86.3 0.0 2.2 2 1 1 3 3 3 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.24 CBK21101.2 - 1.7e-19 69.0 0.0 2.8e-19 68.3 0.0 1.4 1 1 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Fer4_9 PF13187.6 CBK21101.2 - 0.015 15.5 0.4 0.044 14.0 0.4 1.8 1 0 0 1 1 1 0 4Fe-4S dicluster domain RNA_pol_L_2 PF13656.6 CBK21101.2 - 0.046 13.5 0.0 3.2 7.6 0.0 2.5 2 0 0 2 2 2 0 RNA polymerase Rpb3/Rpb11 dimerisation domain zf_CCCH_4 PF18345.1 CBK21103.2 - 4.5e-06 26.5 7.1 8.8e-06 25.6 7.1 1.5 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH_4 PF18044.1 CBK21103.2 - 5.4e-05 22.9 4.3 0.00011 22.0 4.3 1.4 1 0 0 1 1 1 1 CCCH-type zinc finger zf-CCCH PF00642.24 CBK21103.2 - 0.0035 17.2 6.0 0.0065 16.4 6.0 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Neisseria_TspB PF05616.13 CBK21103.2 - 0.77 8.2 5.3 1.1 7.6 5.3 1.2 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein zf-CCCH_2 PF14608.6 CBK21103.2 - 1.2 9.7 5.5 2 9.0 5.5 1.3 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger PHD PF00628.29 CBK21104.2 - 2.5e-08 33.7 0.6 3.4e-08 33.3 0.6 1.2 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.6 CBK21104.2 - 0.0027 17.9 0.1 0.0031 17.7 0.1 1.1 1 0 0 1 1 1 1 PHD-like zinc-binding domain PHD_2 PF13831.6 CBK21104.2 - 0.0051 16.3 2.0 0.0076 15.8 0.2 1.9 2 0 0 2 2 2 1 PHD-finger C1_2 PF03107.16 CBK21104.2 - 0.0061 16.9 3.1 0.008 16.5 3.1 1.2 1 0 0 1 1 1 1 C1 domain Prok-RING_1 PF14446.6 CBK21104.2 - 0.011 15.6 0.7 0.018 14.9 0.7 1.3 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 FANCL_C PF11793.8 CBK21104.2 - 0.018 15.2 0.1 0.03 14.5 0.1 1.5 1 1 0 1 1 1 0 FANCL C-terminal domain C1_1 PF00130.22 CBK21104.2 - 0.059 13.3 3.5 0.12 12.3 3.5 1.5 1 1 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-PHD-like PF15446.6 CBK21104.2 - 0.069 12.8 0.5 0.084 12.5 0.5 1.1 1 0 0 1 1 1 0 PHD/FYVE-zinc-finger like domain WD40 PF00400.32 CBK21105.2 - 5.1e-47 156.9 18.1 1.2e-10 41.8 0.1 7.2 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBK21105.2 - 3.5e-10 40.0 4.4 0.0053 17.0 0.0 5.5 2 2 4 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 CBK21105.2 - 1.6e-06 27.1 7.2 0.015 14.0 0.1 5.0 3 1 1 5 5 5 3 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 CBK21105.2 - 8.6e-06 24.9 0.3 0.04 12.9 0.0 3.6 2 1 2 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein PQQ_2 PF13360.6 CBK21105.2 - 0.0064 16.1 1.7 0.083 12.5 0.0 2.3 2 1 0 2 2 2 1 PQQ-like domain DUF1513 PF07433.11 CBK21105.2 - 0.0091 15.1 0.3 0.97 8.4 0.1 3.1 1 1 1 3 3 3 1 Protein of unknown function (DUF1513) Cytochrom_D1 PF02239.16 CBK21105.2 - 0.02 13.5 0.0 0.94 7.9 0.0 2.9 2 2 1 3 3 3 0 Cytochrome D1 heme domain PQQ_3 PF13570.6 CBK21105.2 - 0.06 13.8 0.5 18 6.0 0.1 3.8 3 1 0 3 3 3 0 PQQ-like domain Ribosomal_L23 PF00276.20 CBK21107.2 - 1.6e-12 47.6 0.1 1.9e-12 47.4 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L23 SapB_1 PF05184.15 CBK21107.2 - 0.12 12.4 0.1 0.21 11.7 0.1 1.4 1 0 0 1 1 1 0 Saposin-like type B, region 1 SKA2 PF16740.5 CBK21108.2 - 0.00033 20.4 15.1 0.00086 19.1 0.9 3.7 1 1 3 4 4 4 1 Spindle and kinetochore-associated protein 2 TPR_MLP1_2 PF07926.12 CBK21108.2 - 0.004 17.2 12.3 0.004 17.2 12.3 3.5 3 1 1 4 4 3 1 TPR/MLP1/MLP2-like protein DUF948 PF06103.11 CBK21108.2 - 0.0098 16.1 2.6 15 5.9 1.2 3.5 2 1 0 3 3 3 0 Bacterial protein of unknown function (DUF948) HALZ PF02183.18 CBK21108.2 - 0.032 14.5 0.7 0.032 14.5 0.7 4.6 5 0 0 5 5 4 0 Homeobox associated leucine zipper FUSC PF04632.12 CBK21108.2 - 0.11 11.1 5.8 0.15 10.5 5.8 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family EspB_PE PF18625.1 CBK21108.2 - 0.12 12.9 1.2 2 8.9 0.0 2.9 2 0 0 2 2 2 0 ESX-1 secreted protein B PE domain Not3 PF04065.15 CBK21108.2 - 0.16 11.4 20.7 0.026 13.9 14.6 2.6 1 1 0 2 2 2 0 Not1 N-terminal domain, CCR4-Not complex component FTO_CTD PF12934.7 CBK21108.2 - 0.17 11.6 0.3 0.17 11.6 0.3 2.4 1 1 1 2 2 2 0 FTO C-terminal domain YabA PF06156.13 CBK21108.2 - 0.25 12.0 20.5 8.5 7.1 6.5 4.7 1 1 3 4 4 4 0 Initiation control protein YabA DUF2894 PF11445.8 CBK21108.2 - 0.37 11.2 9.0 0.11 13.0 4.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2894) Macoilin PF09726.9 CBK21108.2 - 0.47 9.0 21.6 0.45 9.0 20.3 1.6 1 1 0 1 1 1 0 Macoilin family DUF4600 PF15372.6 CBK21108.2 - 0.89 10.0 21.1 1.7 9.1 6.6 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF4600) BRE1 PF08647.11 CBK21108.2 - 0.96 9.6 23.3 0.59 10.3 13.4 3.9 2 1 2 4 4 4 0 BRE1 E3 ubiquitin ligase Tweety PF04906.13 CBK21108.2 - 1.1 7.9 4.8 15 4.1 0.0 2.2 2 0 0 2 2 2 0 Tweety DUF4407 PF14362.6 CBK21108.2 - 1.1 8.6 9.8 3.2 7.0 9.8 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) DUF812 PF05667.11 CBK21108.2 - 1.1 8.0 24.8 0.38 9.6 21.5 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF812) kleA_kleC PF17383.2 CBK21108.2 - 1.3 9.4 7.6 15 6.0 0.1 4.1 3 1 1 4 4 4 0 Uncharacterized KorC regulated protein A DivIC PF04977.15 CBK21108.2 - 1.6 8.5 18.3 3.3 7.5 0.7 5.0 2 1 4 6 6 6 0 Septum formation initiator Sec34 PF04136.15 CBK21108.2 - 2 8.3 14.3 1.2 9.0 6.6 3.3 1 1 2 3 3 3 0 Sec34-like family YlqD PF11068.8 CBK21108.2 - 2.4 8.5 16.3 20 5.6 11.2 3.1 2 1 1 3 3 3 0 YlqD protein Nas2_N PF18265.1 CBK21108.2 - 2.6 8.1 6.4 2.1 8.3 0.5 3.0 3 0 0 3 3 2 0 Nas2 N_terminal domain DUF883 PF05957.13 CBK21108.2 - 2.7 8.7 13.8 0.51 11.0 0.2 3.6 2 1 0 3 3 3 0 Bacterial protein of unknown function (DUF883) DUF2968 PF11180.8 CBK21108.2 - 2.7 7.6 12.8 1.2 8.8 8.1 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF2968) DUF1664 PF07889.12 CBK21108.2 - 3 7.9 9.5 1 9.4 5.4 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) PIN_8 PF18476.1 CBK21108.2 - 3.7 7.4 12.6 26 4.6 10.0 2.2 1 1 1 2 2 2 0 PIN like domain Laminin_II PF06009.12 CBK21108.2 - 5.7 7.0 14.4 1.5 8.9 5.3 2.7 1 1 1 2 2 2 0 Laminin Domain II HAUS6_N PF14661.6 CBK21108.2 - 5.9 6.4 19.5 23 4.5 19.3 2.0 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus CENP-F_leu_zip PF10473.9 CBK21108.2 - 6.2 6.8 30.1 2.1 8.4 7.1 3.6 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 APG6_N PF17675.1 CBK21108.2 - 8.1 7.0 28.7 0.8 10.2 16.3 3.5 2 1 2 4 4 4 0 Apg6 coiled-coil region HSP70 PF00012.20 CBK21109.2 - 1.1e-84 284.7 0.0 1.4e-84 284.4 0.0 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 CBK21109.2 - 3.8e-16 58.8 0.1 6.5e-14 51.5 0.0 2.2 2 0 0 2 2 2 2 MreB/Mbl protein StbA PF06406.11 CBK21109.2 - 0.041 13.1 0.0 0.63 9.2 0.0 2.1 2 0 0 2 2 2 0 StbA protein TPR_14 PF13428.6 CBK21110.2 - 1.6e-26 90.7 16.8 0.0043 17.8 0.1 11.6 6 4 5 11 11 11 6 Tetratricopeptide repeat HAT PF02184.16 CBK21110.2 - 3.2e-23 81.4 45.0 6e-07 29.3 1.1 12.2 12 1 0 12 12 12 7 HAT (Half-A-TPR) repeat Suf PF05843.14 CBK21110.2 - 2.5e-16 60.6 39.6 7e-12 45.9 3.5 7.7 2 2 3 5 5 5 3 Suppressor of forked protein (Suf) TPR_19 PF14559.6 CBK21110.2 - 1.3e-15 57.7 1.1 0.00055 20.4 0.0 6.4 5 2 1 6 6 6 3 Tetratricopeptide repeat Mad3_BUB1_I PF08311.12 CBK21110.2 - 4.6e-11 42.8 25.0 0.00022 21.2 3.2 7.6 7 0 0 7 7 7 3 Mad3/BUB1 homology region 1 TPR_2 PF07719.17 CBK21110.2 - 6.8e-09 35.2 10.4 0.36 11.1 0.2 8.7 10 0 0 10 10 8 2 Tetratricopeptide repeat TPR_17 PF13431.6 CBK21110.2 - 1.2e-08 34.8 1.2 1 9.9 0.0 7.2 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_8 PF13181.6 CBK21110.2 - 9.6e-08 31.7 12.8 3.5 8.1 0.0 9.3 10 0 0 10 10 10 2 Tetratricopeptide repeat TPR_6 PF13174.6 CBK21110.2 - 1.9e-07 31.3 8.7 17 6.3 0.1 9.2 9 0 0 9 9 9 0 Tetratricopeptide repeat TPR_16 PF13432.6 CBK21110.2 - 2.1e-06 28.3 0.3 0.19 12.4 0.0 4.7 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.28 CBK21110.2 - 0.00026 20.7 0.6 5 7.1 0.1 5.1 6 0 0 6 6 6 1 Tetratricopeptide repeat U3_assoc_6 PF08640.11 CBK21110.2 - 0.13 12.4 26.6 0.51 10.4 1.8 7.6 7 3 2 9 9 9 0 U3 small nucleolar RNA-associated protein 6 TPR_9 PF13371.6 CBK21110.2 - 0.15 12.2 4.0 3.4 7.9 0.1 4.8 6 2 0 6 6 5 0 Tetratricopeptide repeat TPR_11 PF13414.6 CBK21110.2 - 0.42 10.3 3.9 6.8 6.5 0.1 3.6 4 0 0 4 4 4 0 TPR repeat BSD PF03909.17 CBK21110.2 - 0.46 10.5 5.8 0.37 10.8 1.1 3.2 3 0 0 3 3 3 0 BSD domain TPR_12 PF13424.6 CBK21110.2 - 0.46 10.8 13.0 9.7 6.6 0.1 6.8 7 1 0 7 7 6 0 Tetratricopeptide repeat ANAPC3 PF12895.7 CBK21110.2 - 0.7 10.2 4.1 3.3 8.0 0.1 3.8 3 1 1 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 Ist1 PF03398.14 CBK21111.2 - 5.8e-12 45.8 4.6 1.1e-11 45.0 4.6 1.4 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway SAPS PF04499.15 CBK21111.2 - 0.3 9.8 14.0 0.36 9.6 14.0 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein CobT PF06213.12 CBK21111.2 - 2.1 7.6 26.6 3 7.1 26.6 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT ASD2 PF08687.11 CBK21111.2 - 2.5 7.6 29.4 0.093 12.3 0.6 2.1 2 0 0 2 2 2 0 Apx/Shroom domain ASD2 GREB1 PF15782.5 CBK21111.2 - 4.4 4.3 15.7 5.3 4.0 15.7 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Presenilin PF01080.17 CBK21111.2 - 9.6 4.9 28.0 14 4.3 28.0 1.2 1 0 0 1 1 1 0 Presenilin GWT1 PF06423.12 CBK21112.2 - 1e-11 45.2 15.1 1e-10 41.9 15.1 2.4 1 1 0 1 1 1 1 GWT1 DUF2177 PF09945.9 CBK21112.2 - 0.88 9.7 12.6 6.6 6.8 9.3 2.6 2 0 0 2 2 2 0 Predicted membrane protein (DUF2177) DUF3989 PF13150.6 CBK21112.2 - 1.3 8.8 0.0 1.3 8.8 0.0 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3989) Prenyltrans PF00432.21 CBK21113.2 - 2.2e-38 129.6 4.3 5.8e-11 41.9 0.1 5.3 5 0 0 5 5 5 5 Prenyltransferase and squalene oxidase repeat RICTOR_N PF14664.6 CBK21114.2 - 0.043 12.8 0.2 0.11 11.5 0.2 1.8 1 1 0 1 1 1 0 Rapamycin-insensitive companion of mTOR, N-term Pkinase PF00069.25 CBK21115.2 - 5.8e-13 48.8 0.0 1.7e-08 34.2 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain DUF3450 PF11932.8 CBK21116.2 - 0.001 18.5 22.3 0.012 14.9 1.2 2.7 2 1 1 3 3 3 2 Protein of unknown function (DUF3450) YabA PF06156.13 CBK21116.2 - 0.014 16.1 16.1 0.079 13.6 1.5 3.1 1 1 2 3 3 3 0 Initiation control protein YabA CASP_C PF08172.12 CBK21116.2 - 0.018 14.4 0.3 0.018 14.4 0.3 2.8 2 1 1 3 3 3 0 CASP C terminal GAS PF13851.6 CBK21116.2 - 0.28 10.5 27.5 0.1 12.0 15.8 2.5 1 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding ZapB PF06005.12 CBK21116.2 - 0.46 11.0 23.0 0.47 10.9 1.1 3.6 2 1 1 3 3 3 0 Cell division protein ZapB Jnk-SapK_ap_N PF09744.9 CBK21116.2 - 0.7 10.1 23.4 0.34 11.1 3.3 2.6 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 Plk4_PB2 PF18409.1 CBK21116.2 - 0.78 10.5 7.2 8.4 7.1 1.7 2.7 2 1 1 3 3 3 0 Polo-like Kinase 4 Polo Box 2 LMBR1 PF04791.16 CBK21116.2 - 1.1 8.1 11.0 1.2 8.0 11.0 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein ATG16 PF08614.11 CBK21116.2 - 1.1 9.4 21.7 0.2 11.8 10.5 2.1 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) HIP1_clath_bdg PF16515.5 CBK21116.2 - 1.3 9.7 21.9 1.2 9.7 10.3 3.3 2 1 1 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 HALZ PF02183.18 CBK21116.2 - 1.6 9.0 16.9 0.48 10.7 0.4 4.3 4 1 0 4 4 4 0 Homeobox associated leucine zipper DUF2524 PF10732.9 CBK21116.2 - 1.9 8.8 8.7 0.37 11.1 4.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2524) DUF2203 PF09969.9 CBK21116.2 - 2.2 9.0 14.8 0.37 11.5 1.6 2.6 2 1 1 3 3 3 0 Uncharacterized conserved protein (DUF2203) ZYG-11_interact PF05884.12 CBK21116.2 - 2.6 7.4 4.0 12 5.2 0.0 2.3 2 1 0 2 2 2 0 Interactor of ZYG-11 ADIP PF11559.8 CBK21116.2 - 5.4 7.1 25.2 1.1 9.3 2.3 3.1 2 1 1 3 3 3 0 Afadin- and alpha -actinin-Binding Sec2p PF06428.11 CBK21116.2 - 6.6 6.8 21.7 1.9 8.5 9.4 3.4 2 2 1 3 3 3 0 GDP/GTP exchange factor Sec2p PRKG1_interact PF15898.5 CBK21116.2 - 9.2 7.2 24.4 4.5e+02 1.8 0.1 3.3 1 1 1 2 2 2 0 cGMP-dependent protein kinase interacting domain Tropomyosin PF00261.20 CBK21117.2 - 0.00056 19.4 4.6 0.00056 19.4 4.6 3.4 2 2 1 3 3 3 2 Tropomyosin GAS PF13851.6 CBK21117.2 - 0.0073 15.7 50.3 0.21 10.9 3.2 3.2 2 1 1 3 3 3 3 Growth-arrest specific micro-tubule binding Golgin_A5 PF09787.9 CBK21117.2 - 0.014 14.9 59.3 0.19 11.1 22.7 3.1 1 1 2 3 3 3 0 Golgin subfamily A member 5 Fez1 PF06818.15 CBK21117.2 - 0.014 15.8 3.2 0.014 15.8 3.2 3.7 1 1 3 4 4 4 0 Fez1 DASH_Hsk3 PF08227.11 CBK21117.2 - 0.02 15.3 7.9 0.02 15.3 7.9 7.4 8 2 0 8 8 6 0 DASH complex subunit Hsk3 like ATG16 PF08614.11 CBK21117.2 - 0.051 13.8 69.0 0.37 11.0 12.0 3.1 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) TMF_TATA_bd PF12325.8 CBK21117.2 - 0.07 13.3 52.3 0.54 10.5 14.1 5.2 1 1 3 5 5 5 0 TATA element modulatory factor 1 TATA binding GCN5L1 PF06320.13 CBK21117.2 - 0.14 12.3 0.2 0.14 12.3 0.2 3.9 1 1 3 4 4 4 0 GCN5-like protein 1 (GCN5L1) TMCO5 PF14992.6 CBK21117.2 - 0.23 11.0 34.3 0.14 11.7 12.0 2.8 1 1 2 3 3 3 0 TMCO5 family PRKG1_interact PF15898.5 CBK21117.2 - 0.44 11.5 52.1 0.1 13.5 19.8 4.3 1 1 3 4 4 4 0 cGMP-dependent protein kinase interacting domain WEMBL PF05701.11 CBK21117.2 - 0.47 9.1 50.8 0.28 9.8 0.9 3.5 1 1 2 3 3 3 0 Weak chloroplast movement under blue light EzrA PF06160.12 CBK21117.2 - 0.5 8.5 40.8 1.5 6.9 2.0 2.9 2 1 0 2 2 2 0 Septation ring formation regulator, EzrA DUF641 PF04859.12 CBK21117.2 - 0.5 10.7 37.9 0.056 13.8 1.3 3.9 2 1 1 3 3 3 0 Plant protein of unknown function (DUF641) HALZ PF02183.18 CBK21117.2 - 0.88 9.8 26.4 0.29 11.4 2.8 5.5 5 1 2 7 7 5 0 Homeobox associated leucine zipper Filament PF00038.21 CBK21117.2 - 1.1 8.7 53.9 0.037 13.6 9.3 3.9 1 1 3 4 4 4 0 Intermediate filament protein AAA_13 PF13166.6 CBK21117.2 - 1.3 7.5 32.9 2.5 6.6 26.9 2.1 2 0 0 2 2 2 0 AAA domain Spc7 PF08317.11 CBK21117.2 - 1.3 7.8 54.3 0.11 11.4 5.4 3.1 1 1 2 3 3 3 0 Spc7 kinetochore protein TACC_C PF05010.14 CBK21117.2 - 1.9 8.2 43.3 0.32 10.7 1.4 3.3 1 1 2 3 3 3 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal Sec8_exocyst PF04048.14 CBK21117.2 - 1.9 8.4 32.9 0.73 9.7 9.1 4.0 1 1 2 4 4 4 0 Sec8 exocyst complex component specific domain YojJ PF10372.9 CBK21117.2 - 2.3 8.4 20.6 2 8.6 1.1 5.2 5 1 0 5 5 5 0 Bacterial membrane-spanning protein N-terminus Seryl_tRNA_N PF02403.22 CBK21117.2 - 4.7 7.5 38.1 0.033 14.4 8.8 4.3 1 1 3 4 4 4 0 Seryl-tRNA synthetase N-terminal domain Tropomyosin_1 PF12718.7 CBK21117.2 - 5 7.3 49.0 0.35 11.0 20.5 3.3 2 1 1 3 3 3 0 Tropomyosin like HMMR_N PF15905.5 CBK21117.2 - 6.3 6.2 43.1 2.2 7.6 0.7 3.1 2 1 1 3 3 3 0 Hyaluronan mediated motility receptor N-terminal DUF1664 PF07889.12 CBK21117.2 - 6.4 6.8 30.7 4.2 7.4 2.9 4.0 1 1 3 5 5 5 0 Protein of unknown function (DUF1664) SKA1 PF07160.12 CBK21117.2 - 7.8 6.3 32.5 2.4 7.9 20.4 3.0 1 1 1 3 3 3 0 Spindle and kinetochore-associated protein 1 Uso1_p115_C PF04871.13 CBK21117.2 - 9.1 6.7 60.9 0.046 14.1 13.1 4.5 1 1 2 4 4 3 0 Uso1 / p115 like vesicle tethering protein, C terminal region MscS_porin PF12795.7 CBK21117.2 - 9.4 5.7 85.2 0.019 14.5 8.4 3.9 2 1 1 3 3 2 0 Mechanosensitive ion channel porin domain TraF_2 PF13729.6 CBK21117.2 - 10 5.4 11.1 20 4.4 10.4 2.3 1 1 0 1 1 1 0 F plasmid transfer operon, TraF, protein GAS PF13851.6 CBK21118.2 - 1.8e-06 27.4 50.5 0.00011 21.7 15.0 3.7 1 1 3 4 4 4 3 Growth-arrest specific micro-tubule binding TMF_DNA_bd PF12329.8 CBK21118.2 - 9.8e-06 25.5 50.6 0.022 14.8 12.8 4.9 3 1 2 5 5 4 4 TATA element modulatory factor 1 DNA binding DUF1664 PF07889.12 CBK21118.2 - 0.00012 22.1 33.7 0.00087 19.3 7.5 4.6 2 1 2 5 5 5 2 Protein of unknown function (DUF1664) ATG16 PF08614.11 CBK21118.2 - 0.00018 21.8 61.9 0.0008 19.7 9.2 4.2 1 1 3 4 4 4 2 Autophagy protein 16 (ATG16) Spc7 PF08317.11 CBK21118.2 - 0.00022 20.2 52.4 0.0017 17.3 19.8 3.3 1 1 3 4 4 4 3 Spc7 kinetochore protein CALCOCO1 PF07888.11 CBK21118.2 - 0.00039 19.4 30.0 0.00039 19.4 30.0 2.6 1 1 1 2 2 2 2 Calcium binding and coiled-coil domain (CALCOCO1) like DUF3584 PF12128.8 CBK21118.2 - 0.00061 17.5 51.3 0.00061 17.5 51.3 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF3584) EzrA PF06160.12 CBK21118.2 - 0.00084 17.6 36.2 0.029 12.6 12.4 2.7 1 1 1 2 2 2 2 Septation ring formation regulator, EzrA phiKZ_IP PF12699.7 CBK21118.2 - 0.0012 18.1 8.3 0.0021 17.3 8.3 1.4 1 0 0 1 1 1 1 phiKZ-like phage internal head proteins HMMR_N PF15905.5 CBK21118.2 - 0.0019 17.7 45.6 0.0032 17.0 17.8 2.6 1 1 1 2 2 2 1 Hyaluronan mediated motility receptor N-terminal TMF_TATA_bd PF12325.8 CBK21118.2 - 0.0026 18.0 50.6 1 9.6 5.6 5.4 2 1 2 5 5 5 3 TATA element modulatory factor 1 TATA binding DUF5082 PF16888.5 CBK21118.2 - 0.0054 17.0 17.3 0.0054 17.0 17.3 5.2 2 1 3 5 5 5 1 Domain of unknown function (DUF5082) BLOC1_2 PF10046.9 CBK21118.2 - 0.0078 16.5 40.0 0.044 14.1 4.7 5.4 2 1 4 6 6 6 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 ADIP PF11559.8 CBK21118.2 - 0.0085 16.2 58.7 0.034 14.2 11.9 4.8 2 1 3 5 5 5 2 Afadin- and alpha -actinin-Binding DivIC PF04977.15 CBK21118.2 - 0.0099 15.6 2.1 0.0099 15.6 2.1 7.6 2 1 3 6 6 5 2 Septum formation initiator HrpB7 PF09486.10 CBK21118.2 - 0.012 16.0 18.3 0.012 16.0 18.3 3.8 2 2 1 3 3 2 0 Bacterial type III secretion protein (HrpB7) Taxilin PF09728.9 CBK21118.2 - 0.014 14.6 40.9 0.013 14.7 10.7 4.0 1 1 3 4 4 4 0 Myosin-like coiled-coil protein Lebercilin PF15619.6 CBK21118.2 - 0.015 15.0 54.1 0.083 12.5 20.3 3.8 2 1 1 3 3 3 0 Ciliary protein causing Leber congenital amaurosis disease DUF641 PF04859.12 CBK21118.2 - 0.017 15.4 3.4 0.017 15.4 3.4 5.0 2 1 2 4 4 3 0 Plant protein of unknown function (DUF641) Filament PF00038.21 CBK21118.2 - 0.02 14.5 47.8 1.7 8.2 26.1 3.8 1 1 2 3 3 3 0 Intermediate filament protein FlaC_arch PF05377.11 CBK21118.2 - 0.034 14.5 0.7 0.034 14.5 0.7 7.1 4 2 2 6 6 5 0 Flagella accessory protein C (FlaC) TRAF_BIRC3_bd PF16673.5 CBK21118.2 - 0.045 13.5 1.1 0.045 13.5 1.1 4.8 5 0 0 5 5 4 0 TNF receptor-associated factor BIRC3 binding domain AAA_13 PF13166.6 CBK21118.2 - 0.049 12.3 39.3 0.12 11.0 25.6 2.5 1 1 1 2 2 2 0 AAA domain ERM PF00769.19 CBK21118.2 - 0.079 12.8 57.0 0.0085 15.9 29.9 3.5 1 1 2 3 3 3 0 Ezrin/radixin/moesin family bZIP_2 PF07716.15 CBK21118.2 - 0.091 12.9 0.1 0.091 12.9 0.1 8.4 8 1 0 8 8 7 0 Basic region leucine zipper ZapB PF06005.12 CBK21118.2 - 0.11 13.0 59.0 1.9 9.0 0.5 6.6 2 1 4 6 6 6 0 Cell division protein ZapB FapA PF03961.13 CBK21118.2 - 0.12 10.9 27.6 0.17 10.4 7.5 2.6 1 1 1 3 3 3 0 Flagellar Assembly Protein A YabA PF06156.13 CBK21118.2 - 0.27 11.9 38.1 1.1 10.0 2.6 5.7 2 1 4 6 6 6 0 Initiation control protein YabA Jnk-SapK_ap_N PF09744.9 CBK21118.2 - 0.29 11.4 56.0 0.22 11.7 11.7 4.8 2 1 3 5 5 5 0 JNK_SAPK-associated protein-1 MAD PF05557.13 CBK21118.2 - 0.32 9.3 57.6 0.052 11.9 20.3 2.9 1 1 1 3 3 3 0 Mitotic checkpoint protein Tropomyosin PF00261.20 CBK21118.2 - 0.47 9.8 43.8 1.4 8.2 9.8 3.8 1 1 1 2 2 2 0 Tropomyosin FPP PF05911.11 CBK21118.2 - 0.93 7.6 45.0 0.14 10.3 17.5 2.2 1 1 1 2 2 2 0 Filament-like plant protein, long coiled-coil Tropomyosin_1 PF12718.7 CBK21118.2 - 1.1 9.5 54.4 0.26 11.5 16.5 4.7 2 1 2 4 4 4 0 Tropomyosin like IFT57 PF10498.9 CBK21118.2 - 1.5 7.7 42.3 4.7 6.1 14.2 3.7 1 1 3 4 4 4 0 Intra-flagellar transport protein 57 Cast PF10174.9 CBK21118.2 - 1.6 6.9 47.2 0.91 7.7 27.2 2.9 1 1 1 2 2 2 0 RIM-binding protein of the cytomatrix active zone Atg14 PF10186.9 CBK21118.2 - 1.7 7.7 53.5 0.78 8.8 14.1 3.8 1 1 2 3 3 3 0 Vacuolar sorting 38 and autophagy-related subunit 14 HIP1_clath_bdg PF16515.5 CBK21118.2 - 2.1 9.0 57.2 0.041 14.5 10.7 5.2 3 2 2 5 5 5 0 Clathrin-binding domain of Huntingtin-interacting protein 1 KASH_CCD PF14662.6 CBK21118.2 - 2.5 7.9 52.6 1.5 8.7 10.1 4.2 2 1 2 4 4 4 0 Coiled-coil region of CCDC155 or KASH DUF724 PF05266.14 CBK21118.2 - 2.8 7.7 40.3 0.14 12.0 12.1 3.5 2 1 2 4 4 3 0 Protein of unknown function (DUF724) Sulfatase_C PF14707.6 CBK21118.2 - 3.8 8.3 19.1 1.4 9.6 0.7 4.7 2 2 4 6 6 6 0 C-terminal region of aryl-sulfatase APG6_N PF17675.1 CBK21118.2 - 4.4 7.8 63.0 0.78 10.3 17.6 4.4 1 1 2 4 4 4 0 Apg6 coiled-coil region BRE1 PF08647.11 CBK21118.2 - 4.8 7.3 49.4 0.052 13.6 7.1 4.9 3 1 2 5 5 5 0 BRE1 E3 ubiquitin ligase HALZ PF02183.18 CBK21118.2 - 6.2 7.1 26.0 19 5.6 0.2 6.7 5 1 1 6 6 6 0 Homeobox associated leucine zipper UPF0242 PF06785.11 CBK21118.2 - 7.6 6.6 59.0 0.53 10.4 18.7 4.3 1 1 3 4 4 4 0 Uncharacterised protein family (UPF0242) N-terminus ACP_PD PF04336.12 CBK21118.2 - 8.6 6.8 17.8 0.59 10.6 1.7 4.3 2 2 1 4 4 4 0 Acyl carrier protein phosphodiesterase DUF4201 PF13870.6 CBK21118.2 - 8.7 6.0 42.8 0.2 11.4 8.6 4.1 2 1 1 4 4 3 0 Domain of unknown function (DUF4201) Ribosomal_L22e PF01776.17 CBK21119.2 - 1.3e-43 147.8 3.8 1.5e-43 147.6 3.8 1.0 1 0 0 1 1 1 1 Ribosomal L22e protein family Glyco_transf_49 PF13896.6 CBK21120.2 - 0.00027 20.4 0.1 0.0004 19.8 0.1 1.2 1 0 0 1 1 1 1 Glycosyl-transferase for dystroglycan Apyrase PF06079.11 CBK21121.2 - 1.1e-122 408.8 3.9 1.4e-122 408.5 3.9 1.1 1 0 0 1 1 1 1 Apyrase adh_short PF00106.25 CBK21122.2 - 5.7e-11 42.2 0.0 1.4e-08 34.4 0.0 2.0 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 CBK21122.2 - 3.8e-07 29.9 0.0 6.8e-07 29.1 0.0 1.6 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 CBK21122.2 - 0.031 13.7 0.0 0.039 13.4 0.0 1.1 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family DUF812 PF05667.11 CBK21123.2 - 0.018 13.9 18.9 0.2 10.5 9.5 2.8 1 1 2 3 3 3 0 Protein of unknown function (DUF812) DUF2590 PF10761.9 CBK21123.2 - 0.045 13.9 0.8 0.22 11.7 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2590) CENP-F_leu_zip PF10473.9 CBK21123.2 - 0.057 13.4 22.3 0.098 12.7 4.1 3.1 2 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Baculo_PEP_C PF04513.12 CBK21123.2 - 0.072 13.1 10.1 0.038 14.0 6.6 2.2 2 2 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus LOH1CR12 PF10158.9 CBK21123.2 - 0.11 12.6 6.2 1.8 8.6 0.8 3.0 1 1 0 2 2 2 0 Tumour suppressor protein Prefoldin PF02996.17 CBK21123.2 - 0.11 12.4 12.9 1.1 9.2 0.1 3.6 2 1 0 3 3 3 0 Prefoldin subunit Sigma70_r4_2 PF08281.12 CBK21123.2 - 0.12 12.0 1.9 2.2 8.0 0.4 2.5 2 0 0 2 2 2 0 Sigma-70, region 4 Fungal_TACC PF12709.7 CBK21123.2 - 0.13 12.8 14.4 7.2 7.1 0.0 3.4 3 0 0 3 3 3 0 Fungal Transforming acidic coiled-coil (TACC) proteins Talin_middle PF09141.10 CBK21123.2 - 0.16 12.0 5.0 0.23 11.5 0.7 2.7 1 1 2 3 3 3 0 Talin, middle domain DUF2203 PF09969.9 CBK21123.2 - 0.24 12.1 7.9 0.34 11.6 4.5 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) MADF_DNA_bdg PF10545.9 CBK21123.2 - 0.48 10.8 6.0 2.9 8.3 2.3 2.4 2 1 0 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like NusB PF01029.18 CBK21123.2 - 1 9.6 9.9 0.17 12.1 1.0 2.4 2 1 1 3 3 3 0 NusB family Seryl_tRNA_N PF02403.22 CBK21123.2 - 1.9 8.8 19.1 1.3 9.3 2.8 3.3 1 1 1 3 3 3 0 Seryl-tRNA synthetase N-terminal domain JIP_LZII PF16471.5 CBK21123.2 - 1.9 8.7 16.0 6.5 7.0 0.0 3.4 2 1 1 3 3 3 0 JNK-interacting protein leucine zipper II TMF_TATA_bd PF12325.8 CBK21123.2 - 2.3 8.5 19.6 2.1 8.6 14.4 2.7 2 1 1 3 3 3 0 TATA element modulatory factor 1 TATA binding TMCO5 PF14992.6 CBK21123.2 - 3.4 7.2 20.7 30 4.0 20.7 2.0 1 1 0 1 1 1 0 TMCO5 family DUF1664 PF07889.12 CBK21123.2 - 3.6 7.7 15.8 6.9 6.7 1.7 3.1 1 1 1 3 3 3 0 Protein of unknown function (DUF1664) bZIP_1 PF00170.21 CBK21123.2 - 3.8 7.7 18.0 1 9.5 0.3 3.9 4 1 0 4 4 3 0 bZIP transcription factor Laminin_II PF06009.12 CBK21123.2 - 4.7 7.2 13.5 0.89 9.6 4.3 2.8 1 1 2 3 3 3 0 Laminin Domain II SlyX PF04102.12 CBK21123.2 - 5 7.8 14.2 1.2 9.8 0.2 3.5 2 1 1 3 3 2 0 SlyX LPP PF04728.13 CBK21123.2 - 6.4 7.3 7.2 14 6.2 0.2 3.3 4 0 0 4 4 4 0 Lipoprotein leucine-zipper LMBR1 PF04791.16 CBK21123.2 - 8.3 5.2 7.5 10 4.9 7.5 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein Phage_HK97_TLTM PF06120.11 CBK21123.2 - 8.8 5.4 14.0 4 6.5 1.2 2.9 1 1 1 3 3 3 0 Tail length tape measure protein CENP-S PF15630.6 CBK21124.2 - 2e-19 69.8 0.0 3.8e-19 68.9 0.0 1.4 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 CBK21124.2 - 1.4e-09 38.0 0.0 2.4e-09 37.3 0.0 1.3 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold Histone PF00125.24 CBK21124.2 - 1.7e-07 31.6 0.7 4.5e-07 30.3 0.1 1.9 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 TFIID-18kDa PF02269.16 CBK21124.2 - 0.0031 17.5 0.4 0.0053 16.8 0.4 1.3 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit Bromo_TP PF07524.13 CBK21124.2 - 0.0032 17.4 0.0 0.0064 16.5 0.0 1.5 1 0 0 1 1 1 1 Bromodomain associated Kinetochor_Ybp2 PF08568.10 CBK21124.2 - 0.028 12.9 0.3 0.035 12.6 0.3 1.1 1 0 0 1 1 1 0 Uncharacterised protein family, YAP/Alf4/glomulin AAA_lid_2 PF17863.1 CBK21124.2 - 0.028 14.3 1.9 0.41 10.5 0.5 2.8 3 0 0 3 3 3 0 AAA lid domain TFIID-31kDa PF02291.15 CBK21124.2 - 0.034 14.2 0.1 0.056 13.5 0.1 1.4 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit TAF PF02969.17 CBK21124.2 - 0.12 12.5 0.0 0.21 11.8 0.0 1.3 1 0 0 1 1 1 0 TATA box binding protein associated factor (TAF) SNF2_N PF00176.23 CBK21125.2 - 3.7e-12 45.7 0.0 5.2e-12 45.2 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain SNF2_N PF00176.23 CBK21126.2 - 3.5e-27 95.0 0.5 6e-27 94.3 0.5 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain GLE1 PF07817.13 CBK21127.2 - 0.00063 19.0 2.4 0.076 12.2 0.2 2.8 1 1 1 2 2 2 2 GLE1-like protein MDM1 PF15501.6 CBK21127.2 - 0.015 14.4 31.8 0.028 13.6 31.8 1.4 1 0 0 1 1 1 0 Nuclear protein MDM1 Tn7_Tnp_TnsA_C PF08721.11 CBK21127.2 - 0.34 11.6 4.3 3.4 8.4 0.4 4.3 3 2 0 3 3 3 0 TnsA endonuclease C terminal Presenilin PF01080.17 CBK21127.2 - 1.9 7.2 26.3 3 6.5 26.3 1.4 1 0 0 1 1 1 0 Presenilin SLC12 PF03522.15 CBK21127.2 - 5.4 5.9 24.3 9.9 5.1 24.3 1.5 1 0 0 1 1 1 0 Solute carrier family 12 TERB2 PF15101.6 CBK21127.2 - 5.4 7.0 14.3 13 5.8 14.3 1.8 1 0 0 1 1 1 0 Telomere-associated protein TERB2 Cpn60_TCP1 PF00118.24 CBK21128.2 - 1.2e-157 525.5 3.1 1.5e-157 525.2 3.1 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family CCDC53 PF10152.9 CBK21129.2 - 5.1e-92 306.2 50.6 5.9e-12 46.3 0.1 11.8 11 1 0 11 11 10 9 Subunit CCDC53 of WASH complex FH2 PF02181.23 CBK21129.2 - 1.3e-67 228.6 10.2 1.3e-67 228.6 10.2 2.0 2 0 0 2 2 1 1 Formin Homology 2 Domain PHD PF00628.29 CBK21129.2 - 1.7e-06 27.8 8.6 6.9e-06 25.9 8.6 2.1 1 1 0 1 1 1 1 PHD-finger Zf_RING PF16744.5 CBK21129.2 - 0.021 14.9 3.2 0.057 13.5 3.2 1.8 1 0 0 1 1 1 0 KIAA1045 RING finger Prok-RING_1 PF14446.6 CBK21129.2 - 0.036 14.0 6.0 0.086 12.8 6.0 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 PHD_4 PF16866.5 CBK21129.2 - 0.053 13.6 5.6 0.15 12.1 5.6 1.9 1 0 0 1 1 1 0 PHD-finger DUF4677 PF15726.5 CBK21129.2 - 0.094 12.9 20.1 23 5.1 0.1 7.3 7 0 0 7 7 7 0 Domain of unknown function (DUF4677) WXG100 PF06013.12 CBK21129.2 - 0.14 12.4 3.3 0.89 9.8 0.3 2.8 1 1 1 2 2 2 0 Proteins of 100 residues with WXG C1_1 PF00130.22 CBK21129.2 - 0.24 11.3 8.3 0.023 14.6 3.1 1.9 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) PLAC PF08686.11 CBK21129.2 - 0.37 11.6 25.5 80 4.1 0.2 7.4 7 0 0 7 7 7 0 PLAC (protease and lacunin) domain APG6_N PF17675.1 CBK21129.2 - 0.6 10.6 11.1 0.61 10.6 0.9 3.0 2 0 0 2 2 2 0 Apg6 coiled-coil region zf-PHD-like PF15446.6 CBK21129.2 - 0.93 9.1 8.2 0.42 10.2 4.9 2.2 2 0 0 2 2 2 0 PHD/FYVE-zinc-finger like domain Snapin_Pallidin PF14712.6 CBK21129.2 - 1.6 9.2 10.8 0.83 10.1 2.2 3.8 3 1 1 4 4 4 0 Snapin/Pallidin Fez1 PF06818.15 CBK21129.2 - 1.7 9.0 14.6 0.2 12.1 9.0 2.4 2 0 0 2 2 1 0 Fez1 LPP PF04728.13 CBK21129.2 - 1.9 8.9 4.0 1.7 9.1 1.6 2.2 2 0 0 2 2 1 0 Lipoprotein leucine-zipper Dict-STAT-coil PF09267.10 CBK21129.2 - 2 8.8 6.8 0.42 11.0 1.0 2.5 2 1 0 2 2 2 0 Dictyostelium STAT, coiled coil zf-RING_9 PF13901.6 CBK21129.2 - 2.1 8.3 8.2 0.77 9.7 3.7 2.6 2 0 0 2 2 2 0 Putative zinc-RING and/or ribbon OrfB_Zn_ribbon PF07282.11 CBK21129.2 - 2.2 8.2 4.2 1.3 9.0 0.5 2.4 2 0 0 2 2 2 0 Putative transposase DNA-binding domain zf-RING_2 PF13639.6 CBK21129.2 - 2.6 8.4 5.7 7.8 6.9 5.7 1.9 1 0 0 1 1 1 0 Ring finger domain DUF3450 PF11932.8 CBK21129.2 - 3.1 7.0 10.4 7.5 5.8 9.7 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF3450) Proteasome PF00227.26 CBK21130.2 - 1.6e-58 197.3 0.0 2e-58 197.0 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 CBK21130.2 - 1e-10 41.1 0.3 1.7e-09 37.1 0.0 2.4 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature HSP70 PF00012.20 CBK21132.2 - 0.00069 17.9 0.0 0.0013 17.1 0.0 1.5 1 1 0 1 1 1 1 Hsp70 protein TGT_C1 PF14809.6 CBK21132.2 - 0.029 14.6 1.0 9 6.7 0.1 3.1 2 1 1 3 3 3 0 C1 domain of tRNA-guanine transglycosylase dimerisation Connexin PF00029.19 CBK21133.2 - 0.23 11.2 1.4 0.37 10.5 1.4 1.3 1 0 0 1 1 1 0 Connexin Paf1 PF03985.13 CBK21133.2 - 8.1 5.3 10.7 11 4.9 10.7 1.1 1 0 0 1 1 1 0 Paf1 Vfa1 PF08432.10 CBK21133.2 - 9.2 6.5 9.5 16 5.7 9.5 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Ribosomal_L6 PF00347.23 CBK21134.2 - 1.1e-26 93.2 4.0 8.5e-14 52.0 0.3 2.1 2 0 0 2 2 2 2 Ribosomal protein L6 Rota_VP4_MID PF17477.2 CBK21134.2 - 0.03 13.7 0.0 0.039 13.3 0.0 1.2 1 0 0 1 1 1 0 Rotavirus VP4 membrane interaction domain Rsm22 PF09243.10 CBK21135.2 - 5.6e-09 35.7 0.0 1e-08 34.8 0.0 1.4 1 1 0 1 1 1 1 Mitochondrial small ribosomal subunit Rsm22 Aminotran_5 PF00266.19 CBK21136.2 - 7.5e-33 114.0 0.0 1.1e-32 113.4 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V DUF4695 PF15766.5 CBK21137.2 - 0.0092 16.2 1.0 0.013 15.8 1.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4695) End3 PF12761.7 CBK21137.2 - 0.022 14.9 3.0 0.33 11.1 0.0 2.8 2 1 0 2 2 2 0 Actin cytoskeleton-regulatory complex protein END3 CAF1 PF04857.20 CBK21137.2 - 0.11 11.7 0.1 0.13 11.4 0.1 1.1 1 0 0 1 1 1 0 CAF1 family ribonuclease CDC45 PF02724.14 CBK21137.2 - 0.12 10.6 2.4 0.14 10.4 2.4 1.0 1 0 0 1 1 1 0 CDC45-like protein PGA2 PF07543.12 CBK21137.2 - 0.25 11.3 6.6 0.31 11.0 6.6 1.1 1 0 0 1 1 1 0 Protein trafficking PGA2 DUF3069 PF11269.8 CBK21137.2 - 0.81 10.0 3.4 1.2 9.4 2.4 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3069) FAM176 PF14851.6 CBK21137.2 - 1.3 8.7 5.6 1.7 8.3 5.6 1.2 1 0 0 1 1 1 0 FAM176 family DUF3811 PF11656.8 CBK21138.2 - 0.017 15.5 0.4 0.045 14.1 0.1 1.8 2 0 0 2 2 2 0 YjbD family (DUF3811) CorA PF01544.18 CBK21139.2 - 2 7.7 7.5 1.6 7.9 5.7 1.6 1 1 0 1 1 1 0 CorA-like Mg2+ transporter protein PROCN PF08083.11 CBK21140.2 - 3.6e-222 737.4 6.9 5.6e-222 736.7 6.9 1.3 1 0 0 1 1 1 1 PROCN (NUC071) domain PRP8_domainIV PF12134.8 CBK21140.2 - 8.6e-115 382.2 1.8 1.6e-114 381.3 1.8 1.5 1 0 0 1 1 1 1 PRP8 domain IV core U6-snRNA_bdg PF10596.9 CBK21140.2 - 3.2e-85 283.9 3.9 8.7e-85 282.5 3.9 1.8 1 0 0 1 1 1 1 U6-snRNA interacting domain of PrP8 PRO8NT PF08082.11 CBK21140.2 - 9.9e-83 275.6 3.8 2.8e-82 274.1 3.1 2.1 2 0 0 2 2 2 1 PRO8NT (NUC069), PrP8 N-terminal domain U5_2-snRNA_bdg PF10597.9 CBK21140.2 - 8.4e-72 239.5 0.0 2.3e-71 238.1 0.0 1.8 1 0 0 1 1 1 1 U5-snRNA binding site 2 of PrP8 RRM_4 PF10598.9 CBK21140.2 - 4.3e-43 145.6 0.1 1.3e-42 144.0 0.1 1.9 1 0 0 1 1 1 1 RNA recognition motif of the spliceosomal PrP8 PROCT PF08084.11 CBK21140.2 - 5.8e-40 136.0 0.0 1.5e-39 134.7 0.0 1.8 1 0 0 1 1 1 1 PROCT (NUC072) domain JAB PF01398.21 CBK21140.2 - 4.4e-07 29.9 0.0 1.6e-06 28.1 0.0 2.1 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease TPR_MLP1_2 PF07926.12 CBK21141.2 - 0.12 12.4 96.5 0.13 12.4 22.4 6.0 3 2 3 6 6 6 0 TPR/MLP1/MLP2-like protein GAS PF13851.6 CBK21141.2 - 0.66 9.3 86.2 0.76 9.1 8.1 6.2 1 1 6 7 7 7 0 Growth-arrest specific micro-tubule binding HALZ PF02183.18 CBK21141.2 - 0.7 10.2 20.5 7.9 6.8 0.3 6.0 6 0 0 6 6 6 0 Homeobox associated leucine zipper Spc7 PF08317.11 CBK21141.2 - 1.2 7.9 93.6 0.6 8.9 11.7 5.3 1 1 4 5 5 5 0 Spc7 kinetochore protein Filament PF00038.21 CBK21141.2 - 6.4 6.3 82.7 0.045 13.3 35.7 4.3 1 1 0 2 2 2 0 Intermediate filament protein Peptidase_M41 PF01434.18 CBK21142.2 - 2.5e-57 193.8 0.2 3.8e-57 193.2 0.2 1.3 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 CBK21142.2 - 7.2e-41 139.7 0.0 1.9e-40 138.3 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CBK21142.2 - 5.3e-12 45.3 0.9 1.1e-11 44.3 0.0 2.0 2 0 0 2 2 1 1 AAA+ lid domain AAA_2 PF07724.14 CBK21142.2 - 0.00068 19.8 0.1 0.0045 17.1 0.0 2.2 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 CBK21142.2 - 0.0027 17.7 0.0 0.0087 16.1 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) FtsH_ext PF06480.15 CBK21142.2 - 0.004 17.5 2.5 0.013 15.8 0.0 2.8 3 0 0 3 3 3 1 FtsH Extracellular AAA_16 PF13191.6 CBK21142.2 - 0.0051 17.2 0.1 0.066 13.6 0.1 2.3 1 1 1 2 2 2 1 AAA ATPase domain TIP49 PF06068.13 CBK21142.2 - 0.0057 15.9 0.1 0.012 14.8 0.1 1.6 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_22 PF13401.6 CBK21142.2 - 0.0083 16.4 0.1 0.3 11.4 0.0 2.6 1 1 1 2 2 2 1 AAA domain RuvB_N PF05496.12 CBK21142.2 - 0.0099 15.6 0.0 0.022 14.5 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_14 PF13173.6 CBK21142.2 - 0.024 14.7 0.0 0.14 12.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 CBK21142.2 - 0.053 14.1 0.1 0.24 11.9 0.0 2.2 2 1 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 CBK21142.2 - 0.069 12.9 0.0 0.16 11.7 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein Mg_chelatase PF01078.21 CBK21142.2 - 0.1 11.9 0.2 0.29 10.5 0.2 1.7 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Sigma54_AID PF00309.20 CBK21142.2 - 1.6 8.7 4.6 0.35 10.8 0.6 2.0 2 0 0 2 2 2 0 Sigma-54 factor, Activator interacting domain (AID) T2SSF PF00482.23 CBK21143.2 - 0.019 14.9 0.4 0.47 10.4 0.0 2.8 3 1 0 3 3 3 0 Type II secretion system (T2SS), protein F AAA_8 PF12780.7 CBK21143.2 - 0.11 11.8 0.1 0.24 10.7 0.1 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region D4 SesA PF17107.5 CBK21143.2 - 0.33 11.2 5.1 0.91 9.7 0.1 2.6 2 1 0 2 2 2 0 N-terminal domain on NACHT_NTPase and P-loop NTPases CCDC-167 PF15188.6 CBK21143.2 - 1.9 8.9 6.2 1.2 9.5 0.9 2.6 2 1 0 2 2 2 0 Coiled-coil domain-containing protein 167 Sld5 PF05916.11 CBK21144.2 - 3.8e-06 27.3 1.1 8.1e-06 26.3 1.1 1.6 1 0 0 1 1 1 1 GINS complex protein Ribosomal_S8e PF01201.22 CBK21145.2 - 3.4e-35 121.2 0.1 4.4e-35 120.8 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein S8e ACR_tran PF00873.19 CBK21146.2 - 0.065 10.9 0.0 0.1 10.2 0.0 1.2 1 0 0 1 1 1 0 AcrB/AcrD/AcrF family Pentapeptide PF00805.22 CBK21148.2 - 0.015 14.9 0.1 0.047 13.4 0.1 1.8 2 0 0 2 2 2 0 Pentapeptide repeats (8 copies) CAP_N PF01213.19 CBK21149.2 - 1.7 8.1 3.5 2.2 7.7 3.5 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal PRIMA1 PF16101.5 CBK21149.2 - 3.1 7.8 6.0 4.6 7.3 6.0 1.4 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 He_PIG PF05345.12 CBK21151.2 - 1.5e-17 63.5 27.1 5.2e-05 23.3 0.1 5.5 5 0 0 5 5 5 4 Putative Ig domain DUF11 PF01345.18 CBK21151.2 - 1.1e-05 25.7 0.1 0.74 10.2 0.0 4.5 2 2 1 3 3 3 2 Domain of unknown function DUF11 I-set PF07679.16 CBK21151.2 - 6e-05 23.0 5.1 2.5 8.2 0.1 4.4 4 0 0 4 4 4 2 Immunoglobulin I-set domain HRM PF02793.22 CBK21151.2 - 0.0067 16.7 12.9 4.1 7.8 0.1 5.2 5 0 0 5 5 5 2 Hormone receptor domain cEGF PF12662.7 CBK21151.2 - 0.22 11.5 5.3 3.2 7.8 0.0 3.6 3 0 0 3 3 3 0 Complement Clr-like EGF-like DUF3185 PF11381.8 CBK21151.2 - 0.31 11.1 4.8 0.87 9.7 4.8 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3185) Arch_flagellin PF01917.16 CBK21151.2 - 1.9 8.7 9.1 0.98 9.6 0.9 3.3 2 1 1 3 3 3 0 Archaebacterial flagellin Ras PF00071.22 CBK21152.2 - 1.1e-16 60.9 0.0 1.3e-09 37.9 0.0 2.3 2 0 0 2 2 2 2 Ras family Roc PF08477.13 CBK21152.2 - 3.8e-14 52.9 0.0 6.6e-09 36.0 0.0 2.8 2 1 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 CBK21152.2 - 1.6e-09 37.8 0.0 9.5e-05 22.5 0.0 2.6 2 1 0 2 2 2 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 CBK21152.2 - 1e-07 32.0 0.0 0.23 11.3 0.0 3.7 4 0 0 4 4 3 2 RsgA GTPase AAA_22 PF13401.6 CBK21152.2 - 2.6e-06 27.7 0.0 0.17 12.2 0.0 2.9 3 0 0 3 3 3 2 AAA domain EF-hand_7 PF13499.6 CBK21152.2 - 2.8e-05 24.5 0.3 0.012 16.0 0.1 2.8 2 0 0 2 2 2 1 EF-hand domain pair AAA_29 PF13555.6 CBK21152.2 - 4.5e-05 23.1 0.0 0.044 13.5 0.0 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_16 PF13191.6 CBK21152.2 - 6.6e-05 23.4 0.0 0.36 11.2 0.0 2.7 2 0 0 2 2 2 2 AAA ATPase domain Arf PF00025.21 CBK21152.2 - 9.4e-05 21.9 0.0 0.00033 20.2 0.0 1.9 1 1 0 1 1 1 1 ADP-ribosylation factor family TniB PF05621.11 CBK21152.2 - 0.00012 21.6 0.0 0.037 13.4 0.0 2.4 2 0 0 2 2 2 1 Bacterial TniB protein EF-hand_1 PF00036.32 CBK21152.2 - 0.00036 19.9 0.7 0.00036 19.9 0.7 2.8 3 0 0 3 3 3 1 EF hand EF_assoc_2 PF08356.12 CBK21152.2 - 0.00046 20.1 0.0 0.0011 18.9 0.0 1.6 1 0 0 1 1 1 1 EF hand associated EF-hand_6 PF13405.6 CBK21152.2 - 0.00075 19.2 0.8 0.00075 19.2 0.8 2.9 3 0 0 3 3 3 1 EF-hand domain AAA_24 PF13479.6 CBK21152.2 - 0.00076 19.3 0.0 0.18 11.5 0.0 2.3 2 0 0 2 2 2 1 AAA domain ATPase_2 PF01637.18 CBK21152.2 - 0.0011 18.9 0.0 1.2 9.0 0.0 2.5 2 0 0 2 2 2 2 ATPase domain predominantly from Archaea ABC_tran PF00005.27 CBK21152.2 - 0.0011 19.4 0.0 1.8 9.1 0.0 2.4 2 0 0 2 2 2 2 ABC transporter Dynamin_N PF00350.23 CBK21152.2 - 0.0021 18.1 0.7 0.52 10.4 0.0 3.3 2 1 2 4 4 4 1 Dynamin family AAA_21 PF13304.6 CBK21152.2 - 0.0029 17.5 0.0 0.043 13.6 0.0 2.3 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system NACHT PF05729.12 CBK21152.2 - 0.0032 17.4 0.1 1.7 8.6 0.0 3.2 2 1 0 2 2 2 1 NACHT domain Gtr1_RagA PF04670.12 CBK21152.2 - 0.0038 16.6 0.3 0.0095 15.3 0.1 1.7 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region AAA_18 PF13238.6 CBK21152.2 - 0.0041 17.7 0.0 3.7 8.1 0.0 2.7 3 0 0 3 3 2 1 AAA domain SPARC_Ca_bdg PF10591.9 CBK21152.2 - 0.0056 17.0 0.2 4.8 7.5 0.1 3.2 2 1 1 3 3 3 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_5 PF13202.6 CBK21152.2 - 0.0096 15.4 0.5 0.021 14.3 0.5 1.6 1 0 0 1 1 1 1 EF hand AAA_23 PF13476.6 CBK21152.2 - 0.01 16.4 0.0 0.095 13.2 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 CBK21152.2 - 0.01 15.3 0.0 3.1 7.3 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region PduV-EutP PF10662.9 CBK21152.2 - 0.015 15.0 0.1 0.47 10.2 0.1 2.9 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation GTP_EFTU PF00009.27 CBK21152.2 - 0.016 14.7 0.0 0.34 10.4 0.0 2.7 3 0 0 3 3 3 0 Elongation factor Tu GTP binding domain FeoB_N PF02421.18 CBK21152.2 - 0.024 14.2 0.2 0.65 9.5 0.2 2.9 2 1 0 2 2 2 0 Ferrous iron transport protein B G-alpha PF00503.20 CBK21152.2 - 0.033 13.4 0.6 0.38 9.9 0.1 2.7 3 1 0 3 3 3 0 G-protein alpha subunit AAA_28 PF13521.6 CBK21152.2 - 0.036 14.3 0.0 5.5 7.2 0.0 2.6 2 1 0 2 2 2 0 AAA domain TsaE PF02367.17 CBK21152.2 - 0.043 13.8 0.0 5.6 7.0 0.0 2.4 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE EF-hand_8 PF13833.6 CBK21152.2 - 0.047 13.5 0.3 0.97 9.3 0.2 3.0 3 0 0 3 3 2 0 EF-hand domain pair MCM PF00493.23 CBK21152.2 - 0.062 12.4 0.0 11 5.1 0.0 2.4 2 0 0 2 2 2 0 MCM P-loop domain Septin PF00735.18 CBK21152.2 - 0.077 12.3 0.0 1.3 8.3 0.0 2.6 3 0 0 3 3 3 0 Septin DUF815 PF05673.13 CBK21152.2 - 0.12 11.6 0.0 1.6 7.8 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF815) MobB PF03205.14 CBK21152.2 - 0.14 12.1 0.0 0.74 9.7 0.0 2.1 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B RNA_helicase PF00910.22 CBK21152.2 - 0.14 12.6 0.0 37 4.8 0.0 3.0 3 0 0 3 3 2 0 RNA helicase Cpn60_TCP1 PF00118.24 CBK21153.2 - 5e-144 480.6 2.7 5.7e-144 480.4 2.7 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Cript PF10235.9 CBK21154.2 - 6.7e-22 77.9 2.3 6.7e-22 77.9 2.3 1.5 2 0 0 2 2 2 1 Microtubule-associated protein CRIPT zinc_ribbon_15 PF17032.5 CBK21154.2 - 0.0018 19.0 8.9 0.013 16.2 5.4 2.6 2 1 0 2 2 2 1 zinc-ribbon family DZR PF12773.7 CBK21154.2 - 0.0018 18.3 5.5 0.017 15.1 3.5 2.5 2 1 0 2 2 2 1 Double zinc ribbon zf-dskA_traR PF01258.17 CBK21154.2 - 0.042 13.8 10.2 0.68 9.9 0.2 3.2 2 1 1 3 3 3 0 Prokaryotic dksA/traR C4-type zinc finger DUF1272 PF06906.11 CBK21154.2 - 0.052 13.6 6.1 0.061 13.4 2.9 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1272) Gin PF10764.9 CBK21154.2 - 0.1 12.5 7.7 3.9 7.5 0.1 2.6 2 1 0 2 2 2 0 Inhibitor of sigma-G Gin zf_UBZ PF18439.1 CBK21154.2 - 0.16 11.6 6.0 0.62 9.7 0.1 3.2 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger zinc-ribbons_6 PF07191.12 CBK21154.2 - 0.17 11.9 6.9 0.69 9.9 2.7 2.3 2 0 0 2 2 2 0 zinc-ribbons DUF2039 PF10217.9 CBK21154.2 - 0.25 11.7 15.4 9.1 6.7 15.4 2.3 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2039) zinc_ribbon_2 PF13240.6 CBK21154.2 - 0.3 10.8 0.1 0.3 10.8 0.1 3.2 3 0 0 3 3 3 0 zinc-ribbon domain zf-FPG_IleRS PF06827.14 CBK21154.2 - 0.65 9.9 0.1 0.65 9.9 0.1 4.0 4 0 0 4 4 4 0 Zinc finger found in FPG and IleRS Sar8_2 PF03058.14 CBK21154.2 - 1.3 9.7 12.4 1.3 9.6 7.8 2.4 2 1 0 2 2 1 0 Sar8.2 family zf-HC5HC2H PF13771.6 CBK21154.2 - 1.5 9.2 10.3 1.6 9.0 6.8 2.4 2 1 0 2 2 2 0 PHD-like zinc-binding domain HNH_5 PF14279.6 CBK21154.2 - 2.5 8.0 9.3 2.9 7.8 0.1 3.7 2 1 1 4 4 4 0 HNH endonuclease zf-B_box PF00643.24 CBK21154.2 - 3.6 7.8 8.7 3.7 7.8 4.0 2.4 2 1 0 2 2 2 0 B-box zinc finger DUF3395 PF11875.8 CBK21155.2 - 2.6e-19 69.6 0.0 7.6e-19 68.1 0.0 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF3395) DnaJ PF00226.31 CBK21155.2 - 2.2e-08 34.1 0.1 6.1e-08 32.7 0.1 1.8 1 1 0 1 1 1 1 DnaJ domain Tubulin PF00091.25 CBK21156.2 - 5.6e-68 229.0 0.0 9.9e-68 228.2 0.0 1.4 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 CBK21156.2 - 2e-46 157.2 0.5 3.1e-46 156.6 0.5 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 CBK21156.2 - 7.9e-05 22.4 0.0 0.00015 21.5 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain AAA_16 PF13191.6 CBK21157.2 - 2e-09 38.0 0.0 2.2e-09 37.9 0.0 1.1 1 0 0 1 1 1 1 AAA ATPase domain AAA PF00004.29 CBK21157.2 - 3.5e-07 30.7 0.0 4.5e-07 30.4 0.0 1.2 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 CBK21157.2 - 7.6e-05 22.3 0.0 9.1e-05 22.0 0.0 1.1 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_19 PF13245.6 CBK21157.2 - 0.00015 22.1 0.0 0.00017 21.9 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 CBK21157.2 - 0.00021 21.6 0.0 0.00029 21.1 0.0 1.2 1 0 0 1 1 1 1 AAA domain ATPase_2 PF01637.18 CBK21157.2 - 0.00028 20.9 0.0 0.00033 20.6 0.0 1.2 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_11 PF13086.6 CBK21157.2 - 0.0016 18.3 0.0 0.0016 18.3 0.0 1.1 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.13 CBK21157.2 - 0.0072 15.6 0.0 0.0078 15.5 0.0 1.1 1 0 0 1 1 1 1 TIP49 P-loop domain NTPase_1 PF03266.15 CBK21157.2 - 0.0092 15.9 0.0 0.011 15.7 0.0 1.2 1 0 0 1 1 1 1 NTPase MeaB PF03308.16 CBK21157.2 - 0.01 14.9 0.0 0.014 14.4 0.0 1.1 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB PIF1 PF05970.14 CBK21157.2 - 0.012 14.8 0.0 0.015 14.5 0.0 1.1 1 0 0 1 1 1 0 PIF1-like helicase KAP_NTPase PF07693.14 CBK21157.2 - 0.014 14.7 0.0 0.016 14.4 0.0 1.0 1 0 0 1 1 1 0 KAP family P-loop domain NB-ARC PF00931.22 CBK21157.2 - 0.016 14.4 0.0 0.019 14.2 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain RNA_helicase PF00910.22 CBK21157.2 - 0.019 15.3 0.0 0.028 14.8 0.0 1.4 1 0 0 1 1 1 0 RNA helicase AAA_30 PF13604.6 CBK21157.2 - 0.027 14.2 0.0 0.029 14.1 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 CBK21157.2 - 0.03 14.4 0.0 0.045 13.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.15 CBK21157.2 - 0.037 13.9 0.0 0.041 13.8 0.0 1.1 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_18 PF13238.6 CBK21157.2 - 0.044 14.3 0.0 0.084 13.4 0.0 1.6 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 CBK21157.2 - 0.11 12.7 0.0 0.15 12.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 CBK21157.2 - 0.11 12.4 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 NACHT domain Viral_helicase1 PF01443.18 CBK21157.2 - 0.13 12.0 0.0 0.14 11.9 0.0 1.2 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_5 PF07728.14 CBK21157.2 - 0.16 12.0 0.0 0.19 11.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) UvrD-helicase PF00580.21 CBK21157.2 - 0.18 11.3 0.0 0.2 11.2 0.0 1.2 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain TSC22 PF01166.18 CBK21157.2 - 1.3 9.4 3.3 27 5.1 0.3 2.3 2 0 0 2 2 2 0 TSC-22/dip/bun family AAA_lid_10 PF17872.1 CBK21158.2 - 1.9e-08 34.3 0.5 3e-08 33.7 0.4 1.5 1 1 0 1 1 1 1 AAA lid domain AAA PF00004.29 CBK21158.2 - 3.4e-05 24.3 0.3 6.5e-05 23.4 0.1 1.5 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) GAS PF13851.6 CBK21160.2 - 7.7e-06 25.4 16.8 1.1e-05 24.9 16.8 1.2 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding TPR_MLP1_2 PF07926.12 CBK21160.2 - 6.4e-05 23.0 22.0 0.00013 22.0 22.1 1.4 1 1 0 1 1 1 1 TPR/MLP1/MLP2-like protein FAM184 PF15665.5 CBK21160.2 - 0.0001 22.2 15.7 0.00013 21.8 15.7 1.1 1 0 0 1 1 1 1 Family with sequence similarity 184, A and B ERM PF00769.19 CBK21160.2 - 0.00033 20.6 11.9 0.00043 20.2 11.9 1.1 1 0 0 1 1 1 1 Ezrin/radixin/moesin family Golgin_A5 PF09787.9 CBK21160.2 - 0.00039 20.0 18.7 0.00047 19.7 18.7 1.1 1 0 0 1 1 1 1 Golgin subfamily A member 5 Lipoprotein_7 PF01540.16 CBK21160.2 - 0.00043 19.7 9.8 0.0006 19.2 9.8 1.2 1 0 0 1 1 1 1 Adhesin lipoprotein Apolipoprotein PF01442.18 CBK21160.2 - 0.0005 20.0 17.0 0.0011 18.9 15.5 1.9 1 1 1 2 2 2 1 Apolipoprotein A1/A4/E domain Spc7 PF08317.11 CBK21160.2 - 0.00053 19.0 16.0 0.00074 18.5 16.0 1.3 1 0 0 1 1 1 1 Spc7 kinetochore protein YkyA PF10368.9 CBK21160.2 - 0.00067 19.4 18.6 0.00094 18.9 18.6 1.2 1 0 0 1 1 1 1 Putative cell-wall binding lipoprotein DUF4200 PF13863.6 CBK21160.2 - 0.00075 19.9 20.6 0.0059 17.0 9.9 2.4 1 1 1 2 2 2 2 Domain of unknown function (DUF4200) DUF2046 PF09755.9 CBK21160.2 - 0.0013 18.1 13.1 0.0013 18.1 13.1 2.0 1 1 1 2 2 2 1 Uncharacterized conserved protein H4 (DUF2046) DUF3584 PF12128.8 CBK21160.2 - 0.0014 16.3 12.1 0.0016 16.1 12.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) DUF3450 PF11932.8 CBK21160.2 - 0.0016 17.8 15.7 0.0036 16.7 15.7 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF3450) TMF_TATA_bd PF12325.8 CBK21160.2 - 0.003 17.8 13.9 0.003 17.8 13.9 2.2 1 1 1 2 2 2 1 TATA element modulatory factor 1 TATA binding UPF0242 PF06785.11 CBK21160.2 - 0.003 17.7 18.1 0.004 17.3 18.1 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0242) N-terminus Tup_N PF08581.10 CBK21160.2 - 0.0034 17.6 19.4 0.033 14.5 12.9 3.2 1 1 1 2 2 2 1 Tup N-terminal Filament PF00038.21 CBK21160.2 - 0.0042 16.7 18.7 0.0082 15.8 12.3 2.0 1 1 1 2 2 2 2 Intermediate filament protein Seryl_tRNA_N PF02403.22 CBK21160.2 - 0.0044 17.2 16.9 0.018 15.3 10.2 2.1 1 1 1 2 2 2 1 Seryl-tRNA synthetase N-terminal domain MbeD_MobD PF04899.12 CBK21160.2 - 0.0059 16.7 5.3 0.13 12.4 1.5 2.3 1 1 1 2 2 2 1 MbeD/MobD like HAUS-augmin3 PF14932.6 CBK21160.2 - 0.0062 16.1 12.5 0.009 15.6 12.5 1.3 1 0 0 1 1 1 1 HAUS augmin-like complex subunit 3 ATG16 PF08614.11 CBK21160.2 - 0.0062 16.8 20.3 0.021 15.0 20.4 1.7 1 1 0 1 1 1 1 Autophagy protein 16 (ATG16) DUF2408 PF10303.9 CBK21160.2 - 0.0071 16.9 11.8 0.0071 16.9 11.8 1.5 2 0 0 2 2 1 1 Protein of unknown function (DUF2408) V_ATPase_I PF01496.19 CBK21160.2 - 0.0099 13.9 11.3 0.012 13.6 11.3 1.1 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family Atg14 PF10186.9 CBK21160.2 - 0.012 14.7 14.2 0.016 14.3 14.2 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Alpha-2-MRAP_C PF06401.11 CBK21160.2 - 0.013 15.4 16.3 0.058 13.3 16.3 1.8 1 1 0 1 1 1 0 Alpha-2-macroglobulin RAP, C-terminal domain Lebercilin PF15619.6 CBK21160.2 - 0.021 14.5 22.1 0.091 12.4 22.1 2.1 1 1 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease Vps51 PF08700.11 CBK21160.2 - 0.022 14.9 11.7 0.026 14.6 4.7 3.2 1 1 1 2 2 2 0 Vps51/Vps67 Tropomyosin_1 PF12718.7 CBK21160.2 - 0.022 14.9 25.4 0.14 12.3 24.2 2.0 1 1 1 2 2 2 0 Tropomyosin like LPP PF04728.13 CBK21160.2 - 0.027 14.9 11.9 0.03 14.7 2.5 3.6 4 0 0 4 4 3 0 Lipoprotein leucine-zipper HMMR_N PF15905.5 CBK21160.2 - 0.028 13.9 22.7 0.49 9.8 22.2 2.0 1 1 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal DUF1640 PF07798.11 CBK21160.2 - 0.034 14.2 14.9 0.047 13.8 14.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) Baculo_PEP_C PF04513.12 CBK21160.2 - 0.035 14.1 5.5 0.029 14.4 3.1 1.8 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Exonuc_VII_L PF02601.15 CBK21160.2 - 0.037 13.6 8.5 0.049 13.2 8.5 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit AAA_13 PF13166.6 CBK21160.2 - 0.039 12.6 16.5 0.054 12.1 15.2 1.6 1 1 1 2 2 2 0 AAA domain HrpB7 PF09486.10 CBK21160.2 - 0.044 14.2 6.8 0.12 12.8 6.8 1.6 1 1 0 1 1 1 0 Bacterial type III secretion protein (HrpB7) Rootletin PF15035.6 CBK21160.2 - 0.046 13.8 15.8 0.12 12.4 15.8 1.7 1 1 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion IFT57 PF10498.9 CBK21160.2 - 0.047 12.6 13.7 0.058 12.4 13.7 1.2 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 Mod_r PF07200.13 CBK21160.2 - 0.051 13.7 22.2 0.048 13.8 10.6 2.2 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein kleA_kleC PF17383.2 CBK21160.2 - 0.053 13.8 0.6 0.053 13.8 0.6 2.8 2 1 1 3 3 2 0 Uncharacterized KorC regulated protein A Prominin PF05478.11 CBK21160.2 - 0.055 11.4 7.3 0.066 11.2 7.3 1.1 1 0 0 1 1 1 0 Prominin FliJ PF02050.16 CBK21160.2 - 0.058 13.6 16.0 0.15 12.3 13.7 2.1 1 1 1 2 2 2 0 Flagellar FliJ protein CCDC84 PF14968.6 CBK21160.2 - 0.061 12.9 7.4 0.078 12.6 7.4 1.1 1 0 0 1 1 1 0 Coiled coil protein 84 ApoLp-III PF07464.11 CBK21160.2 - 0.063 13.4 14.7 0.085 12.9 13.7 1.7 1 1 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) SOGA PF11365.8 CBK21160.2 - 0.063 14.4 4.7 0.063 14.4 4.7 2.3 1 1 1 2 2 2 0 Protein SOGA Spectrin PF00435.21 CBK21160.2 - 0.076 13.5 14.0 0.028 14.9 5.2 2.3 1 1 1 2 2 2 0 Spectrin repeat COG5 PF10392.9 CBK21160.2 - 0.077 13.2 14.9 0.084 13.0 13.0 1.7 1 1 1 2 2 2 0 Golgi transport complex subunit 5 DUF4407 PF14362.6 CBK21160.2 - 0.077 12.3 11.7 0.15 11.4 11.5 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Fez1 PF06818.15 CBK21160.2 - 0.081 13.4 19.8 0.89 10.0 6.1 2.0 1 1 1 2 2 2 0 Fez1 DUF5082 PF16888.5 CBK21160.2 - 0.081 13.2 18.3 0.14 12.4 18.3 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF5082) DUF2935 PF11155.8 CBK21160.2 - 0.082 13.2 4.5 3.4 8.0 1.9 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF2935) Leu_zip PF15294.6 CBK21160.2 - 0.089 12.3 17.7 0.65 9.5 17.8 1.8 1 1 0 1 1 1 0 Leucine zipper DUF4455 PF14643.6 CBK21160.2 - 0.11 11.2 17.5 0.032 12.9 9.1 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4455) Nup88 PF10168.9 CBK21160.2 - 0.12 10.2 11.3 0.15 9.9 11.3 1.2 1 0 0 1 1 1 0 Nuclear pore component CEP63 PF17045.5 CBK21160.2 - 0.14 12.1 20.3 1.6 8.6 20.2 2.0 1 1 0 1 1 1 0 Centrosomal protein of 63 kDa YtxH PF12732.7 CBK21160.2 - 0.14 12.7 13.9 1.8 9.2 2.2 2.5 1 1 1 2 2 2 0 YtxH-like protein Tho2 PF11262.8 CBK21160.2 - 0.15 11.2 11.3 0.24 10.6 11.3 1.3 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 LXG PF04740.12 CBK21160.2 - 0.15 11.7 16.1 0.52 10.0 3.8 2.2 1 1 1 2 2 2 0 LXG domain of WXG superfamily Laminin_I PF06008.14 CBK21160.2 - 0.17 11.5 15.5 2.8 7.6 0.3 2.1 1 1 1 2 2 2 0 Laminin Domain I KELK PF15796.5 CBK21160.2 - 0.18 12.3 21.6 0.12 12.8 6.2 2.9 1 1 2 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase TMF_DNA_bd PF12329.8 CBK21160.2 - 0.18 11.8 25.7 0.35 10.9 17.6 2.3 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding Med30 PF11315.8 CBK21160.2 - 0.18 12.0 15.2 0.14 12.4 9.9 2.2 1 1 1 2 2 2 0 Mediator complex subunit 30 Rho_Binding PF08912.11 CBK21160.2 - 0.21 12.4 21.4 0.43 11.4 10.9 2.6 2 1 0 2 2 2 0 Rho Binding XRN_M PF17846.1 CBK21160.2 - 0.22 10.4 10.9 0.26 10.2 10.9 1.0 1 0 0 1 1 1 0 Xrn1 helical domain CortBP2 PF09727.9 CBK21160.2 - 0.22 11.4 18.7 0.42 10.5 18.7 1.5 1 1 0 1 1 1 0 Cortactin-binding protein-2 BLOC1_2 PF10046.9 CBK21160.2 - 0.26 11.6 15.7 0.72 10.2 9.7 2.5 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF445 PF04286.12 CBK21160.2 - 0.26 11.1 9.3 0.33 10.7 9.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF445) DUF883 PF05957.13 CBK21160.2 - 0.27 11.8 11.7 3.5 8.3 5.0 2.3 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) OmpH PF03938.14 CBK21160.2 - 0.31 11.4 18.4 0.45 10.9 13.2 2.1 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) Ead_Ea22 PF13935.6 CBK21160.2 - 0.31 11.7 10.1 21 5.8 10.1 2.2 1 1 0 1 1 1 0 Ead/Ea22-like protein DUF3138 PF11336.8 CBK21160.2 - 0.32 9.6 0.9 1.5 7.4 0.3 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3138) MRP-S26 PF14943.6 CBK21160.2 - 0.39 10.6 13.5 0.53 10.2 13.5 1.1 1 0 0 1 1 1 0 Mitochondrial ribosome subunit S26 DUF948 PF06103.11 CBK21160.2 - 0.41 10.9 7.7 7.9 6.8 7.7 2.5 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) Swi5 PF07061.11 CBK21160.2 - 0.43 10.7 18.9 2.6 8.2 8.6 2.9 1 1 0 2 2 2 0 Swi5 APG6_N PF17675.1 CBK21160.2 - 0.48 10.9 23.7 2.8 8.5 22.5 2.1 1 1 1 2 2 2 0 Apg6 coiled-coil region FlxA PF14282.6 CBK21160.2 - 0.49 10.4 23.4 1.1 9.3 15.4 2.4 1 1 1 2 2 2 0 FlxA-like protein Spc24 PF08286.11 CBK21160.2 - 0.53 10.6 19.6 0.79 10.0 7.7 3.0 1 1 2 3 3 3 0 Spc24 subunit of Ndc80 Csm1_N PF18504.1 CBK21160.2 - 0.53 10.7 22.9 1 9.7 5.2 3.4 1 1 2 3 3 3 0 Csm1 N-terminal domain Occludin_ELL PF07303.13 CBK21160.2 - 0.63 10.8 15.9 2.6 8.8 9.5 2.3 1 1 1 2 2 2 0 Occludin homology domain Syntaxin_2 PF14523.6 CBK21160.2 - 0.65 10.4 18.1 0.59 10.5 12.8 2.2 1 1 1 2 2 2 0 Syntaxin-like protein DUF1515 PF07439.11 CBK21160.2 - 0.7 9.9 6.9 0.99 9.5 2.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1515) HIP1_clath_bdg PF16515.5 CBK21160.2 - 0.7 10.5 20.7 0.27 11.9 7.1 2.4 1 1 2 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Fzo_mitofusin PF04799.13 CBK21160.2 - 0.76 9.3 13.6 0.35 10.4 8.0 2.2 1 1 2 3 3 3 0 fzo-like conserved region bZIP_1 PF00170.21 CBK21160.2 - 0.88 9.7 16.2 0.38 10.9 5.3 3.1 2 1 1 3 3 3 0 bZIP transcription factor DUF3490 PF11995.8 CBK21160.2 - 0.89 9.4 8.9 0.82 9.5 7.7 1.5 1 1 1 2 2 1 0 Domain of unknown function (DUF3490) PRKG1_interact PF15898.5 CBK21160.2 - 0.91 10.5 20.3 1.2 10.1 12.3 2.2 1 1 1 2 2 2 0 cGMP-dependent protein kinase interacting domain DUF1664 PF07889.12 CBK21160.2 - 0.95 9.5 13.9 1.3 9.1 8.5 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Bacillus_HBL PF05791.11 CBK21160.2 - 1 9.2 13.1 2 8.2 5.0 2.1 1 1 1 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) HAUS6_N PF14661.6 CBK21160.2 - 1.1 8.8 14.2 2 8.0 14.2 1.4 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus YlqD PF11068.8 CBK21160.2 - 1.1 9.7 17.6 0.28 11.5 11.6 2.0 1 1 1 2 2 2 0 YlqD protein DUF4795 PF16043.5 CBK21160.2 - 1.3 8.6 20.0 2.5 7.6 2.9 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4795) GrpE PF01025.19 CBK21160.2 - 1.3 8.6 15.5 2.3 7.8 14.8 1.7 1 1 0 1 1 1 0 GrpE MCPsignal PF00015.21 CBK21160.2 - 1.6 8.5 8.1 2.3 8.0 7.5 1.6 1 1 1 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Sec8_exocyst PF04048.14 CBK21160.2 - 1.6 8.6 14.3 8 6.3 4.9 2.6 1 1 2 3 3 2 0 Sec8 exocyst complex component specific domain ZapB PF06005.12 CBK21160.2 - 1.7 9.2 22.1 17 5.9 14.4 3.0 1 1 1 2 2 2 0 Cell division protein ZapB Phage_GPO PF05929.11 CBK21160.2 - 1.8 8.1 11.6 3 7.4 11.6 1.4 1 1 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase DUF641 PF04859.12 CBK21160.2 - 1.9 8.9 18.1 12 6.2 1.1 2.9 1 1 2 3 3 3 0 Plant protein of unknown function (DUF641) Cnn_1N PF07989.11 CBK21160.2 - 1.9 8.7 21.2 1.7 8.9 5.9 3.2 1 1 2 3 3 3 0 Centrosomin N-terminal motif 1 Fib_alpha PF08702.10 CBK21160.2 - 2.1 8.5 16.7 20 5.4 16.7 2.0 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family TMPIT PF07851.13 CBK21160.2 - 2.2 7.5 17.6 8.3 5.6 17.6 1.8 1 1 0 1 1 1 0 TMPIT-like protein LMBR1 PF04791.16 CBK21160.2 - 2.2 7.1 9.4 2.6 6.8 9.4 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF2203 PF09969.9 CBK21160.2 - 2.2 9.0 13.6 3.6 8.3 3.1 2.2 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) COG2 PF06148.11 CBK21160.2 - 2.6 8.2 15.1 7.7 6.6 1.4 2.7 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF4665 PF15679.5 CBK21160.2 - 2.6 8.7 10.5 1.1 9.9 8.2 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4665) Laminin_II PF06009.12 CBK21160.2 - 2.7 8.0 15.0 2.1 8.4 6.6 2.0 1 1 1 2 2 2 0 Laminin Domain II Phage_Mu_Gam PF07352.12 CBK21160.2 - 2.9 7.8 15.7 0.48 10.3 6.1 2.2 1 1 1 2 2 2 0 Bacteriophage Mu Gam like protein BST2 PF16716.5 CBK21160.2 - 3.2 8.4 17.9 39 4.9 0.7 2.8 1 1 2 3 3 3 0 Bone marrow stromal antigen 2 Lectin_N PF03954.14 CBK21160.2 - 3.3 7.5 12.2 5.3 6.8 6.6 2.3 1 1 1 2 2 2 0 Hepatic lectin, N-terminal domain IFT20 PF14931.6 CBK21160.2 - 4 7.6 18.5 0.24 11.6 8.9 2.2 1 1 1 2 2 2 0 Intraflagellar transport complex B, subunit 20 Vfa1 PF08432.10 CBK21160.2 - 4 7.7 13.2 5.1 7.4 13.2 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 ApoO PF09769.9 CBK21160.2 - 4.4 7.3 6.8 74 3.3 6.8 2.4 1 1 0 1 1 1 0 Apolipoprotein O DUF3573 PF12097.8 CBK21160.2 - 4.4 6.0 5.3 4.9 5.9 5.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) Ax_dynein_light PF10211.9 CBK21160.2 - 4.7 7.1 21.4 1 9.2 12.4 2.0 1 1 1 2 2 2 0 Axonemal dynein light chain NPV_P10 PF05531.12 CBK21160.2 - 4.8 7.7 10.9 6.1e+02 1.0 10.9 3.0 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein SlyX PF04102.12 CBK21160.2 - 4.9 7.9 13.2 2.6 8.7 3.1 3.2 1 1 2 3 3 3 0 SlyX Mt_ATP-synt_D PF05873.12 CBK21160.2 - 5.5 6.8 12.1 27 4.6 12.1 2.1 1 1 0 1 1 1 0 ATP synthase D chain, mitochondrial (ATP5H) ADIP PF11559.8 CBK21160.2 - 6.7 6.8 20.9 3.6 7.7 13.2 2.0 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding Adhesin_P1_N PF18652.1 CBK21160.2 - 7.6 6.6 11.2 0.6 10.2 2.8 2.9 1 1 1 3 3 3 0 Adhesin P1 N-terminal domain zf-C4H2 PF10146.9 CBK21160.2 - 7.7 6.8 17.0 11 6.3 17.0 1.2 1 0 0 1 1 1 0 Zinc finger-containing protein CCDC-167 PF15188.6 CBK21160.2 - 7.7 6.9 18.4 2.5e+03 -1.1 18.4 3.0 1 1 0 1 1 0 0 Coiled-coil domain-containing protein 167 DUF724 PF05266.14 CBK21160.2 - 9 6.1 19.6 9.4 6.0 3.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF724) CENP-H PF05837.12 CBK21160.2 - 9.1 6.7 20.0 9.9 6.6 13.8 2.1 1 1 2 3 3 3 0 Centromere protein H (CENP-H) MctB PF11382.8 CBK21160.2 - 9.6 5.8 7.6 2.3 7.9 2.8 2.1 1 1 1 2 2 2 0 Copper transport outer membrane protein, MctB FHA PF00498.26 CBK21161.2 - 2.4e-07 31.0 0.0 3.5e-07 30.5 0.0 1.3 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 CBK21161.2 - 0.04 14.2 0.0 0.1 12.9 0.0 1.6 2 0 0 2 2 2 0 Inner membrane component of T3SS, cytoplasmic domain CAF1 PF04857.20 CBK21163.2 - 3.4e-24 85.6 0.4 4e-14 52.5 0.1 2.2 1 1 1 2 2 2 2 CAF1 family ribonuclease DNA_pol_A_exo1 PF01612.20 CBK21163.2 - 0.0045 16.7 0.0 0.48 10.1 0.0 2.2 2 0 0 2 2 2 2 3'-5' exonuclease RNase_H_2 PF13482.6 CBK21163.2 - 0.013 15.5 0.0 0.023 14.7 0.0 1.4 1 0 0 1 1 1 0 RNase_H superfamily Vint PF14623.6 CBK21163.2 - 0.16 11.7 0.0 0.25 11.1 0.0 1.2 1 0 0 1 1 1 0 Hint-domain Ras PF00071.22 CBK21164.2 - 8.5e-38 129.5 0.6 1e-37 129.2 0.6 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CBK21164.2 - 7.1e-27 94.0 0.2 1.2e-26 93.3 0.2 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CBK21164.2 - 4.4e-15 55.6 0.6 5.4e-15 55.3 0.6 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 CBK21164.2 - 3.9e-06 26.4 0.2 5.1e-06 26.0 0.2 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 CBK21164.2 - 7.8e-06 26.0 0.1 1.2e-05 25.3 0.1 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 CBK21164.2 - 1.2e-05 24.9 0.4 1.5e-05 24.5 0.4 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 CBK21164.2 - 1.8e-05 24.4 0.4 0.0014 18.2 0.4 2.3 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_7 PF12775.7 CBK21164.2 - 0.00042 19.9 0.1 0.0007 19.2 0.1 1.4 1 1 0 1 1 1 1 P-loop containing dynein motor region AAA_16 PF13191.6 CBK21164.2 - 0.0015 18.9 0.0 0.0017 18.8 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain PduV-EutP PF10662.9 CBK21164.2 - 0.0019 17.9 0.7 1.2 8.9 0.0 2.4 1 1 0 2 2 2 2 Ethanolamine utilisation - propanediol utilisation MMR_HSR1_Xtn PF16897.5 CBK21164.2 - 0.0059 16.6 3.4 0.02 14.9 0.3 2.4 1 1 1 2 2 2 1 C-terminal region of MMR_HSR1 domain G-alpha PF00503.20 CBK21164.2 - 0.0072 15.5 0.5 0.026 13.7 0.5 2.0 1 1 0 1 1 1 1 G-protein alpha subunit AAA_22 PF13401.6 CBK21164.2 - 0.0074 16.6 0.0 0.061 13.6 0.0 2.0 1 1 0 1 1 1 1 AAA domain DUF2726 PF10881.8 CBK21164.2 - 0.008 16.1 0.0 0.019 14.9 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2726) RsgA_GTPase PF03193.16 CBK21164.2 - 0.01 15.7 0.6 0.17 11.8 0.1 2.3 1 1 2 3 3 3 0 RsgA GTPase TniB PF05621.11 CBK21164.2 - 0.028 13.8 0.0 0.16 11.4 0.0 1.9 2 0 0 2 2 2 0 Bacterial TniB protein FeoB_N PF02421.18 CBK21164.2 - 0.096 12.2 0.4 0.47 10.0 0.4 2.0 1 1 0 1 1 1 0 Ferrous iron transport protein B NB-ARC PF00931.22 CBK21164.2 - 0.51 9.5 4.5 18 4.4 4.5 2.8 1 1 0 1 1 1 0 NB-ARC domain HSP90 PF00183.18 CBK21165.2 - 2.8e-219 729.3 26.9 3.6e-219 729.0 26.9 1.1 1 0 0 1 1 1 1 Hsp90 protein HATPase_c PF02518.26 CBK21165.2 - 2.1e-15 57.2 0.1 3.9e-15 56.3 0.1 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 CBK21165.2 - 1.1e-10 41.5 0.1 2.7e-10 40.2 0.1 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Sulfatase_C PF14707.6 CBK21165.2 - 0.19 12.4 2.2 0.2 12.4 0.1 2.1 2 0 0 2 2 2 0 C-terminal region of aryl-sulfatase RRM_1 PF00076.22 CBK21166.2 - 8.6e-34 115.2 0.0 1.3e-16 60.2 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CBK21166.2 - 1.1e-08 35.1 0.0 0.0072 16.4 0.0 3.0 3 0 0 3 3 3 2 RNA recognition motif Nup35_RRM_2 PF14605.6 CBK21166.2 - 0.011 15.7 0.0 0.4 10.7 0.0 2.3 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif PHM7_cyt PF14703.6 CBK21166.2 - 0.019 15.2 3.3 0.63 10.2 1.8 2.8 2 1 0 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter RRM_Rrp7 PF17799.1 CBK21166.2 - 0.042 13.7 0.1 8.6 6.1 0.0 2.9 1 1 2 3 3 3 0 Rrp7 RRM-like N-terminal domain DNA_topoisoIV PF00521.20 CBK21166.2 - 0.058 12.3 1.5 0.33 9.8 0.5 2.0 1 1 1 2 2 2 0 DNA gyrase/topoisomerase IV, subunit A Limkain-b1 PF11608.8 CBK21166.2 - 0.073 13.2 0.1 2.5 8.2 0.0 2.5 2 0 0 2 2 2 0 Limkain b1 RNA_pol_Rpc4 PF05132.14 CBK21166.2 - 0.6 10.5 5.1 3.5 8.0 0.2 2.6 3 0 0 3 3 3 0 RNA polymerase III RPC4 LRR_8 PF13855.6 CBK21167.2 - 0.08 12.7 0.9 2.5 7.9 0.0 3.1 2 1 0 3 3 3 0 Leucine rich repeat AAA PF00004.29 CBK21168.2 - 1.9e-40 138.3 0.0 6.9e-40 136.5 0.0 2.0 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CBK21168.2 - 1.9e-09 37.2 0.1 4.6e-09 35.9 0.1 1.7 1 0 0 1 1 1 1 AAA+ lid domain AAA_2 PF07724.14 CBK21168.2 - 3.8e-06 27.1 0.2 1.9e-05 24.8 0.0 2.2 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 CBK21168.2 - 2.8e-05 24.1 0.0 0.00017 21.6 0.0 2.3 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 CBK21168.2 - 3.8e-05 24.1 0.3 0.0032 17.9 0.0 2.6 2 1 1 3 3 2 1 AAA ATPase domain AAA_22 PF13401.6 CBK21168.2 - 8.6e-05 22.8 0.1 0.0069 16.7 0.0 2.5 1 1 1 2 2 2 1 AAA domain RNA_helicase PF00910.22 CBK21168.2 - 0.0019 18.5 0.0 0.086 13.2 0.0 2.9 2 1 0 2 2 2 1 RNA helicase DUF815 PF05673.13 CBK21168.2 - 0.0026 17.0 0.0 0.0065 15.7 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF815) RuvB_N PF05496.12 CBK21168.2 - 0.0058 16.4 0.0 0.013 15.2 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_14 PF13173.6 CBK21168.2 - 0.013 15.5 0.0 0.43 10.6 0.0 2.7 2 1 0 2 2 2 0 AAA domain ATPase_2 PF01637.18 CBK21168.2 - 0.018 15.0 1.4 14 5.5 0.0 3.5 2 2 2 4 4 4 0 ATPase domain predominantly from Archaea BLOC1_2 PF10046.9 CBK21168.2 - 0.02 15.2 1.9 0.066 13.5 0.6 2.5 3 0 0 3 3 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 AAA_33 PF13671.6 CBK21168.2 - 0.025 14.8 0.0 0.081 13.1 0.0 1.9 2 0 0 2 2 1 0 AAA domain AAA_28 PF13521.6 CBK21168.2 - 0.029 14.6 0.1 0.053 13.8 0.1 1.4 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 CBK21168.2 - 0.034 13.7 0.1 0.16 11.5 0.0 2.1 2 1 0 2 2 2 0 P-loop containing dynein motor region AAA_3 PF07726.11 CBK21168.2 - 0.059 13.2 0.0 0.14 12.0 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 CBK21168.2 - 0.067 12.9 0.1 0.32 10.7 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 CBK21168.2 - 0.067 12.9 1.4 0.18 11.5 0.0 2.4 4 1 0 4 4 4 0 AAA domain AAA_18 PF13238.6 CBK21168.2 - 0.085 13.4 0.0 0.26 11.8 0.0 1.9 2 0 0 2 2 1 0 AAA domain AAA_11 PF13086.6 CBK21168.2 - 0.094 12.5 0.8 0.57 9.9 0.0 2.1 2 0 0 2 2 2 0 AAA domain Mg_chelatase PF01078.21 CBK21168.2 - 0.094 12.1 0.0 0.21 10.9 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI DUF4094 PF13334.6 CBK21168.2 - 0.15 12.5 2.2 23 5.5 0.5 3.2 2 1 1 3 3 3 0 Domain of unknown function (DUF4094) RRM_2 PF04059.12 CBK21169.2 - 1.6e-22 79.5 0.0 3.2e-22 78.6 0.0 1.5 2 0 0 2 2 2 1 RNA recognition motif 2 RRM_1 PF00076.22 CBK21169.2 - 0.00042 20.1 0.0 0.00069 19.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) UNC-50 PF05216.13 CBK21170.2 - 1.2e-55 188.5 18.9 1.3e-55 188.3 18.9 1.0 1 0 0 1 1 1 1 UNC-50 family DUF1129 PF06570.11 CBK21170.2 - 0.1 12.1 6.8 0.036 13.5 4.1 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1129) COX2-transmemb PF09125.10 CBK21170.2 - 1.6 8.6 7.2 2.1 8.2 1.8 2.7 2 0 0 2 2 2 0 Cytochrome C oxidase subunit II, transmembrane COX14 PF14880.6 CBK21170.2 - 2.5 8.0 4.6 12 5.8 0.6 3.0 3 0 0 3 3 3 0 Cytochrome oxidase c assembly Virul_fac_BrkB PF03631.15 CBK21170.2 - 8.8 5.9 21.9 0.69 9.5 6.3 2.1 1 1 1 2 2 2 0 Virulence factor BrkB WD40 PF00400.32 CBK21171.2 - 6.6e-12 45.7 1.5 0.25 12.3 0.0 6.2 6 0 0 6 6 6 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBK21171.2 - 4.4e-07 30.1 0.1 0.44 10.9 0.0 4.9 2 2 3 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 CBK21171.2 - 5.3e-05 22.3 0.5 0.67 8.9 0.1 4.2 2 1 2 5 5 5 2 WD40 region of Ge1, enhancer of mRNA-decapping protein PQQ_2 PF13360.6 CBK21171.2 - 6.1e-05 22.7 0.0 0.00084 19.0 0.0 2.0 1 1 0 1 1 1 1 PQQ-like domain SDA1 PF05285.12 CBK21171.2 - 0.00039 19.9 10.2 0.00046 19.7 10.2 1.1 1 0 0 1 1 1 1 SDA1 BUD22 PF09073.10 CBK21171.2 - 0.00051 19.5 7.8 0.00066 19.1 7.8 1.1 1 0 0 1 1 1 1 BUD22 Utp8 PF10395.9 CBK21171.2 - 0.008 14.7 0.0 0.015 13.9 0.0 1.4 1 0 0 1 1 1 1 Utp8 family PHTB1_N PF14727.6 CBK21171.2 - 0.037 13.4 0.0 7.3 5.8 0.0 2.3 1 1 0 2 2 2 0 PTHB1 N-terminus PQQ PF01011.21 CBK21171.2 - 0.078 12.9 0.0 0.25 11.4 0.0 1.9 1 0 0 1 1 1 0 PQQ enzyme repeat Mpp10 PF04006.12 CBK21171.2 - 0.086 11.3 19.1 0.12 10.8 19.1 1.1 1 0 0 1 1 1 0 Mpp10 protein CobT PF06213.12 CBK21171.2 - 0.1 11.9 13.1 0.15 11.4 13.1 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT RNA_pol_Rpc4 PF05132.14 CBK21171.2 - 0.1 13.0 3.7 0.16 12.4 3.7 1.2 1 0 0 1 1 1 0 RNA polymerase III RPC4 Frtz PF11768.8 CBK21171.2 - 0.11 10.8 0.6 1.5 7.0 0.0 2.4 3 0 0 3 3 3 0 WD repeat-containing and planar cell polarity effector protein Fritz CDC45 PF02724.14 CBK21171.2 - 0.12 10.7 15.5 0.16 10.2 15.5 1.1 1 0 0 1 1 1 0 CDC45-like protein DNA_pol_phi PF04931.13 CBK21171.2 - 1.3 7.0 20.2 1.8 6.6 20.2 1.1 1 0 0 1 1 1 0 DNA polymerase phi Nop14 PF04147.12 CBK21171.2 - 2.6 6.1 18.3 4 5.5 18.3 1.2 1 0 0 1 1 1 0 Nop14-like family DUF2151 PF10221.9 CBK21171.2 - 3 6.3 7.0 4.4 5.8 7.0 1.1 1 0 0 1 1 1 0 Cell cycle and development regulator Ank_2 PF12796.7 CBK21172.2 - 1.5e-21 76.8 3.5 1.8e-12 47.7 0.1 3.0 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 CBK21172.2 - 2.4e-16 59.6 1.3 1.8e-07 31.3 0.1 3.8 2 2 2 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 CBK21172.2 - 7.8e-12 45.1 2.9 0.00022 21.5 0.0 4.4 5 0 0 5 5 5 2 Ankyrin repeat Ank_4 PF13637.6 CBK21172.2 - 2.2e-11 44.0 4.2 1e-07 32.3 0.0 3.6 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 CBK21172.2 - 2.4e-11 42.8 7.6 0.0016 18.8 0.0 6.0 6 0 0 6 6 6 2 Ankyrin repeat Collagen PF01391.18 CBK21172.2 - 0.0032 17.2 8.1 0.0032 17.2 8.1 1.6 2 0 0 2 2 2 1 Collagen triple helix repeat (20 copies) Spt20 PF12090.8 CBK21172.2 - 0.33 10.5 14.1 0.48 10.0 14.1 1.1 1 0 0 1 1 1 0 Spt20 family DUF4175 PF13779.6 CBK21172.2 - 0.41 8.5 12.2 0.61 7.9 12.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) TFIIA PF03153.13 CBK21172.2 - 0.51 10.3 11.0 0.77 9.7 11.0 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit eIF-3_zeta PF05091.12 CBK21172.2 - 1.8 7.5 4.8 2.6 6.9 4.8 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF773 PF05600.12 CBK21174.2 - 0.0037 16.0 0.2 0.073 11.8 0.2 2.1 2 0 0 2 2 2 1 CDK5 regulatory subunit-associated protein 3 MSA-2c PF12238.8 CBK21174.2 - 0.019 15.0 1.8 0.036 14.1 1.8 1.4 1 0 0 1 1 1 0 Merozoite surface antigen 2c Med9 PF07544.13 CBK21174.2 - 0.087 12.9 0.3 0.33 11.0 0.0 2.1 2 0 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 DUF1043 PF06295.12 CBK21174.2 - 0.11 12.5 0.1 0.29 11.1 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) ATG16 PF08614.11 CBK21174.2 - 0.11 12.7 5.8 0.19 11.9 5.8 1.4 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) DUF4554 PF15091.6 CBK21174.2 - 1.9 7.3 6.2 2.7 6.8 6.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4554) EF-hand_6 PF13405.6 CBK21175.2 - 1.6e-09 36.9 0.0 0.00022 20.9 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 CBK21175.2 - 2.5e-09 36.2 0.1 0.00098 18.5 0.0 2.2 2 0 0 2 2 2 2 EF hand EF-hand_1 PF00036.32 CBK21175.2 - 2.8e-09 35.9 0.1 0.00065 19.1 0.0 2.2 2 0 0 2 2 2 2 EF hand EF-hand_4 PF12763.7 CBK21175.2 - 2e-08 34.1 0.0 2.7e-08 33.7 0.0 1.1 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand EF-hand_7 PF13499.6 CBK21175.2 - 8.8e-08 32.5 1.3 2.6e-05 24.6 0.2 2.1 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 CBK21175.2 - 1.7e-05 24.5 0.1 0.01 15.7 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain pair SPARC_Ca_bdg PF10591.9 CBK21175.2 - 0.0039 17.5 0.1 0.0075 16.6 0.1 1.4 1 1 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_10 PF14788.6 CBK21175.2 - 0.034 14.0 0.0 1.8 8.5 0.0 2.1 2 0 0 2 2 2 0 EF hand Dockerin_1 PF00404.18 CBK21175.2 - 0.073 13.3 0.0 4.8 7.4 0.0 2.1 2 0 0 2 2 2 0 Dockerin type I domain Sorb PF02208.16 CBK21175.2 - 0.086 12.7 0.2 0.17 11.8 0.2 1.5 1 0 0 1 1 1 0 Sorbin homologous domain Pescadillo_N PF06732.11 CBK21176.2 - 8.3e-111 369.9 0.5 1.1e-110 369.5 0.5 1.1 1 0 0 1 1 1 1 Pescadillo N-terminus BRCT_2 PF16589.5 CBK21177.2 - 3.9e-08 33.6 0.0 8.4e-08 32.5 0.0 1.6 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 CBK21177.2 - 1.9e-05 24.9 0.0 4.9e-05 23.6 0.0 1.8 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain LIG3_BRCT PF16759.5 CBK21177.2 - 0.012 15.9 0.0 0.051 13.9 0.0 2.1 1 1 0 1 1 1 0 DNA ligase 3 BRCT domain zf-C3HC4_3 PF13920.6 CBK21178.2 - 2e-14 53.2 18.4 4.9e-14 51.9 18.4 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 CBK21178.2 - 1e-05 25.3 17.2 2.8e-05 23.9 17.2 1.7 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 CBK21178.2 - 0.00023 21.4 20.3 0.00023 21.4 20.3 2.0 2 0 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.6 CBK21178.2 - 0.0029 17.5 17.2 0.0087 16.0 17.2 1.9 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 CBK21178.2 - 0.12 12.3 19.9 0.42 10.5 19.9 2.0 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Nop16 PF09420.10 CBK21179.2 - 4.6e-10 39.9 0.3 5.3e-10 39.7 0.3 1.1 1 0 0 1 1 1 1 Ribosome biogenesis protein Nop16 Ribosomal_L7Ae PF01248.26 CBK21180.2 - 1.3e-23 82.5 0.1 1.6e-23 82.3 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Hydrolase_4 PF12146.8 CBK21181.2 - 6e-07 29.0 0.0 9.2e-07 28.4 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 CBK21181.2 - 2.9e-05 24.8 0.0 9.3e-05 23.1 0.0 1.8 2 0 0 2 2 2 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.18 CBK21181.2 - 0.0013 18.4 0.0 0.0018 17.9 0.0 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Peptidase_S9 PF00326.21 CBK21181.2 - 0.087 12.3 0.0 0.17 11.3 0.0 1.4 1 1 0 1 1 1 0 Prolyl oligopeptidase family PFK PF00365.20 CBK21183.2 - 8.6e-27 94.2 0.0 6.4e-26 91.3 0.0 2.1 1 1 0 1 1 1 1 Phosphofructokinase RsgA_N PF16745.5 CBK21183.2 - 0.055 13.2 0.1 6.9 6.5 0.0 2.5 2 0 0 2 2 2 0 RsgA N-terminal domain LRR_4 PF12799.7 CBK21184.2 - 0.034 14.6 0.7 0.19 12.2 0.3 2.2 2 0 0 2 2 2 0 Leucine Rich repeats (2 copies) N2227 PF07942.12 CBK21185.2 - 9.2e-81 271.0 0.1 1e-80 270.8 0.1 1.0 1 0 0 1 1 1 1 N2227-like protein Methyltransf_23 PF13489.6 CBK21185.2 - 0.00097 19.0 0.0 0.0013 18.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CBK21185.2 - 0.0018 19.0 0.0 0.0084 16.8 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CBK21185.2 - 0.027 15.1 0.0 0.28 11.8 0.0 2.5 3 0 0 3 3 3 0 Methyltransferase domain Relaxase PF03432.14 CBK21185.2 - 0.043 13.4 0.1 0.064 12.9 0.1 1.2 1 0 0 1 1 1 0 Relaxase/Mobilisation nuclease domain Pept_tRNA_hydro PF01195.19 CBK21186.2 - 1.2e-49 168.5 0.0 2e-49 167.9 0.0 1.3 1 1 0 1 1 1 1 Peptidyl-tRNA hydrolase NPL4 PF05021.15 CBK21187.2 - 1.7e-15 57.2 0.0 2.4e-08 33.7 0.0 2.2 1 1 1 2 2 2 2 NPL4 family zf-NPL4 PF05020.15 CBK21187.2 - 2.2e-12 47.3 10.0 2.2e-12 47.3 10.0 3.4 1 1 2 3 3 3 2 NPL4 family, putative zinc binding region zf-4CXXC_R1 PF10497.9 CBK21187.2 - 8.3 6.7 16.5 1 9.7 7.8 2.8 1 1 1 2 2 2 0 Zinc-finger domain of monoamine-oxidase A repressor R1 Pkinase PF00069.25 CBK21189.2 - 1.1e-41 143.0 0.0 1.2e-41 142.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBK21189.2 - 1.8e-29 102.8 0.0 2.3e-29 102.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CBK21189.2 - 0.0082 15.0 0.0 0.011 14.6 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Seadorna_VP7 PF07387.11 CBK21189.2 - 0.15 11.1 0.1 0.22 10.6 0.1 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 UQ_con PF00179.26 CBK21190.2 - 4.2e-49 165.8 0.0 5.3e-49 165.5 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 CBK21190.2 - 1.8e-05 24.5 0.0 2.3e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 CBK21190.2 - 0.015 15.6 0.0 0.022 15.1 0.0 1.6 1 1 0 1 1 1 0 RWD domain RNA_pol_Rpb1_1 PF04997.12 CBK21190.2 - 0.021 14.2 0.1 0.027 13.8 0.1 1.1 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 1 DEAD PF00270.29 CBK21191.2 - 2.5e-37 128.3 0.0 6.8e-37 126.9 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CBK21191.2 - 3.8e-25 88.4 0.0 3.6e-24 85.3 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 CBK21191.2 - 8e-05 22.7 0.1 0.00029 20.9 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit zf-met PF12874.7 CBK21191.2 - 0.00035 20.9 1.2 0.00082 19.7 0.3 2.2 2 0 0 2 2 2 1 Zinc-finger of C2H2 type Helicase_C_2 PF13307.6 CBK21191.2 - 0.014 15.5 0.1 0.035 14.3 0.0 1.7 2 0 0 2 2 2 0 Helicase C-terminal domain zf-C2H2_jaz PF12171.8 CBK21191.2 - 0.018 15.3 0.4 0.05 13.9 0.4 1.8 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding CpXC PF14353.6 CBK21191.2 - 0.033 14.2 1.7 0.043 13.9 0.2 1.9 2 0 0 2 2 2 0 CpXC protein zf-C2H2 PF00096.26 CBK21191.2 - 0.047 14.2 2.4 0.059 13.8 0.1 2.4 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf_C2H2_ZHX PF18387.1 CBK21191.2 - 0.078 12.6 0.4 0.21 11.3 0.4 1.7 1 0 0 1 1 1 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-C2H2_4 PF13894.6 CBK21191.2 - 0.92 10.5 2.7 1.6 9.8 0.1 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger Eapp_C PF10238.9 CBK21191.2 - 1.2 9.2 7.2 3.7 7.6 1.8 2.6 2 0 0 2 2 2 0 E2F-associated phosphoprotein CAC1F_C PF16885.5 CBK21191.2 - 8 6.0 8.9 1 8.9 4.9 1.5 2 0 0 2 2 2 0 Voltage-gated calcium channel subunit alpha, C-term Ribosomal_L32e PF01655.18 CBK21192.2 - 3.2e-47 159.4 0.1 4e-47 159.1 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L32 DNA_pol_A_exo1 PF01612.20 CBK21193.2 - 0.0013 18.5 0.0 0.0015 18.3 0.0 1.2 1 0 0 1 1 1 1 3'-5' exonuclease TFIID-31kDa PF02291.15 CBK21194.2 - 4.1e-12 46.2 0.1 4.7e-12 46.0 0.1 1.1 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 CBK21194.2 - 0.0056 16.7 0.0 0.0073 16.3 0.0 1.2 1 0 0 1 1 1 1 Bromodomain associated Histone PF00125.24 CBK21194.2 - 0.021 15.2 0.0 0.034 14.5 0.0 1.5 1 0 0 1 1 1 0 Core histone H2A/H2B/H3/H4 Ribosomal_L2_C PF03947.18 CBK21195.2 - 1.4e-45 154.6 1.6 2.1e-45 154.0 1.6 1.2 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 CBK21195.2 - 1.2e-14 54.0 0.1 3.4e-14 52.6 0.0 1.9 2 0 0 2 2 2 1 Ribosomal Proteins L2, RNA binding domain H_PPase PF03030.16 CBK21196.2 - 2.8e-255 849.0 25.4 3.3e-255 848.8 25.4 1.0 1 0 0 1 1 1 1 Inorganic H+ pyrophosphatase LMBR1 PF04791.16 CBK21198.2 - 3.5e-23 82.3 1.0 3.7e-23 82.2 1.0 1.0 1 0 0 1 1 1 1 LMBR1-like membrane protein LMBR1 PF04791.16 CBK21199.2 - 8.3e-11 41.5 7.9 9.5e-11 41.3 7.9 1.0 1 0 0 1 1 1 1 LMBR1-like membrane protein Ank_4 PF13637.6 CBK21200.2 - 6.7e-28 96.7 3.0 8.6e-09 35.8 0.0 6.0 1 1 5 6 6 6 6 Ankyrin repeats (many copies) Ank_2 PF12796.7 CBK21200.2 - 1.4e-25 89.6 6.3 1.6e-12 47.9 0.0 2.9 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 CBK21200.2 - 2.3e-25 88.3 6.3 3.2e-07 30.5 0.3 4.7 3 1 2 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 CBK21200.2 - 6.9e-19 66.0 3.5 0.0011 19.3 0.0 5.7 6 0 0 6 6 6 4 Ankyrin repeat Ank PF00023.30 CBK21200.2 - 2.8e-18 65.4 10.8 0.00045 20.5 0.0 5.7 6 1 0 6 6 6 5 Ankyrin repeat Ribosomal_L7Ae PF01248.26 CBK21201.2 - 9.4e-25 86.2 0.2 1.2e-24 85.9 0.2 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Glyco_hydro_85 PF03644.13 CBK21202.2 - 7.9e-52 176.5 0.0 1e-51 176.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 85 Zn_ribbon_17 PF17120.5 CBK21203.2 - 3e-06 26.7 11.1 5.4e-06 25.9 11.1 1.4 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zinc_ribbon_16 PF17034.5 CBK21203.2 - 8.2e-05 22.8 6.9 0.00024 21.3 6.9 1.7 1 1 1 2 2 2 1 Zinc-ribbon like family DUF3565 PF12088.8 CBK21203.2 - 0.085 12.8 1.6 0.19 11.7 1.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3565) WD40 PF00400.32 CBK21204.2 - 4.5e-05 24.1 2.9 0.94 10.5 0.3 4.9 4 0 0 4 4 4 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBK21204.2 - 0.00017 21.8 0.1 3.1 8.2 0.0 3.7 1 1 2 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain PH PF00169.29 CBK21205.2 - 6e-09 36.4 0.1 7.7e-09 36.0 0.1 1.2 1 0 0 1 1 1 1 PH domain PH_8 PF15409.6 CBK21205.2 - 1.6e-06 28.3 0.1 2.5e-06 27.7 0.1 1.3 1 1 0 1 1 1 1 Pleckstrin homology domain PH_11 PF15413.6 CBK21205.2 - 0.00049 20.5 0.5 0.0048 17.3 0.5 2.0 1 1 0 1 1 1 1 Pleckstrin homology domain Band_7 PF01145.25 CBK21206.2 - 1.1e-28 100.4 0.4 1.1e-28 100.4 0.4 1.6 2 0 0 2 2 2 1 SPFH domain / Band 7 family Band_7_1 PF13421.6 CBK21206.2 - 0.013 15.2 0.3 0.027 14.2 0.3 1.5 1 0 0 1 1 1 0 SPFH domain-Band 7 family TrwC PF08751.11 CBK21206.2 - 0.014 15.0 2.0 0.014 15.0 2.0 2.0 1 1 0 2 2 2 0 TrwC relaxase Ribul_P_3_epim PF00834.19 CBK21207.2 - 1.8e-66 223.3 0.4 2.1e-66 223.1 0.4 1.0 1 0 0 1 1 1 1 Ribulose-phosphate 3 epimerase family QRPTase_C PF01729.19 CBK21207.2 - 0.018 14.8 0.1 0.027 14.3 0.1 1.5 1 1 0 1 1 1 0 Quinolinate phosphoribosyl transferase, C-terminal domain Band_7 PF01145.25 CBK21208.2 - 5.6e-29 101.4 0.4 1.1e-28 100.4 0.4 1.5 1 0 0 1 1 1 1 SPFH domain / Band 7 family TrwC PF08751.11 CBK21208.2 - 0.013 15.1 2.0 0.013 15.1 2.0 2.0 1 1 1 2 2 2 0 TrwC relaxase Band_7_1 PF13421.6 CBK21208.2 - 0.013 15.2 0.3 0.027 14.2 0.3 1.5 1 0 0 1 1 1 0 SPFH domain-Band 7 family Band_7 PF01145.25 CBK21209.2 - 8.3e-22 78.0 2.4 8.3e-22 78.0 2.4 2.3 1 1 1 2 2 2 1 SPFH domain / Band 7 family DivIVA PF05103.13 CBK21209.2 - 0.0049 17.0 5.8 0.011 15.9 5.8 1.5 1 0 0 1 1 1 1 DivIVA protein Yqai PF09466.10 CBK21209.2 - 0.032 14.5 0.1 0.084 13.2 0.1 1.7 1 0 0 1 1 1 0 Hypothetical protein Yqai V-ATPase_G_2 PF16999.5 CBK21209.2 - 0.039 14.4 8.3 0.047 14.1 7.5 1.5 1 1 0 1 1 1 0 Vacuolar (H+)-ATPase G subunit Caudo_TAP PF02413.17 CBK21209.2 - 0.29 11.3 5.1 1.7 8.8 5.1 2.0 1 1 0 1 1 1 0 Caudovirales tail fibre assembly protein, lambda gpK Flot PF15975.5 CBK21209.2 - 0.46 10.7 6.0 4.6 7.4 6.1 2.2 1 1 1 2 2 2 0 Flotillin V-ATPase_G PF03179.15 CBK21209.2 - 0.97 10.0 11.3 0.11 13.0 3.7 2.2 1 1 1 2 2 2 0 Vacuolar (H+)-ATPase G subunit ArfGap PF01412.18 CBK21210.2 - 2.7e-18 66.1 1.4 6.4e-18 64.9 1.4 1.6 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf CDC45 PF02724.14 CBK21210.2 - 0.34 9.2 5.3 0.4 8.9 5.3 1.2 1 0 0 1 1 1 0 CDC45-like protein YchF-GTPase_C PF06071.13 CBK21211.2 - 2e-39 133.6 1.3 5.1e-39 132.3 0.7 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.23 CBK21211.2 - 6.9e-21 74.5 0.0 1.8e-20 73.1 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 CBK21211.2 - 5.8e-07 29.2 0.0 1.5e-06 27.8 0.0 1.7 1 0 0 1 1 1 1 Ferrous iron transport protein B TGS PF02824.21 CBK21211.2 - 0.012 15.6 0.0 0.024 14.7 0.0 1.5 1 0 0 1 1 1 0 TGS domain MeaB PF03308.16 CBK21211.2 - 0.018 14.1 0.0 0.041 12.8 0.0 1.6 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_18 PF13238.6 CBK21211.2 - 0.022 15.3 0.0 0.1 13.1 0.0 2.1 2 0 0 2 2 2 0 AAA domain Dynamin_N PF00350.23 CBK21211.2 - 0.091 12.8 0.0 0.62 10.1 0.0 2.5 1 1 0 1 1 1 0 Dynamin family DEAD PF00270.29 CBK21212.2 - 1e-50 172.0 0.0 3.7e-50 170.1 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CBK21212.2 - 2.6e-30 105.0 0.1 1.3e-29 102.7 0.3 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 CBK21212.2 - 0.00079 19.5 0.0 0.0023 18.0 0.0 1.7 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 CBK21212.2 - 0.059 12.6 0.1 0.097 11.9 0.1 1.3 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase GRP PF07172.11 CBK21212.2 - 3.6 8.3 17.4 0.12 13.1 7.6 2.4 2 0 0 2 2 2 0 Glycine rich protein family PHD PF00628.29 CBK21213.2 - 7.1e-09 35.4 58.6 0.00013 21.8 11.1 4.4 4 1 0 4 4 4 3 PHD-finger zf-HC5HC2H_2 PF13832.6 CBK21213.2 - 0.023 14.9 43.1 0.045 13.9 20.9 3.3 1 1 2 3 3 3 0 PHD-zinc-finger like domain DUF563 PF04577.14 CBK21214.2 - 2.8e-16 60.3 2.3 3.4e-16 60.0 0.4 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF563) Pneumo_M2 PF07380.11 CBK21214.2 - 0.0075 16.5 1.4 0.026 14.8 1.4 1.9 1 0 0 1 1 1 1 Pneumovirus M2 protein Nucleotid_trans PF03407.16 CBK21215.2 - 1.2e-19 71.2 0.1 2e-19 70.4 0.1 1.3 1 0 0 1 1 1 1 Nucleotide-diphospho-sugar transferase O-FucT PF10250.9 CBK21215.2 - 0.00037 20.3 0.3 0.0006 19.6 0.3 1.3 1 0 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase Glyco_transf_49 PF13896.6 CBK21216.2 - 3.1e-09 36.6 3.5 5.9e-09 35.7 0.4 2.4 2 1 0 2 2 2 1 Glycosyl-transferase for dystroglycan FBA_1 PF07734.13 CBK21216.2 - 0.00045 20.2 1.0 0.0015 18.5 0.5 2.0 1 1 1 2 2 2 2 F-box associated RNase_P_pop3 PF08228.11 CBK21217.2 - 0.079 13.0 0.0 0.15 12.1 0.0 1.3 1 0 0 1 1 1 0 RNase P subunit Pop3 Ribosomal_L7Ae PF01248.26 CBK21218.2 - 0.023 14.4 0.0 0.042 13.6 0.0 1.5 1 0 0 1 1 1 0 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Cas9_C PF18525.1 CBK21218.2 - 0.14 12.3 0.0 0.2 11.9 0.0 1.1 1 0 0 1 1 1 0 Cas9 C-terminal domain RNA_helicase PF00910.22 CBK21220.2 - 8.5e-10 39.0 0.1 4.7e-09 36.6 0.1 2.3 2 1 0 2 2 2 1 RNA helicase ATPase_2 PF01637.18 CBK21220.2 - 0.19 11.6 0.8 2.3 8.1 0.0 2.8 3 1 1 4 4 4 0 ATPase domain predominantly from Archaea RNA_helicase PF00910.22 CBK21221.2 - 9.1e-09 35.7 0.0 3.9e-08 33.6 0.0 2.1 2 0 0 2 2 2 1 RNA helicase ATPase_2 PF01637.18 CBK21221.2 - 0.11 12.4 0.1 1.5 8.7 0.0 2.4 2 1 1 3 3 3 0 ATPase domain predominantly from Archaea SNF2_N PF00176.23 CBK21222.2 - 1.6e-71 240.9 3.1 5.1e-71 239.2 3.1 1.8 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 CBK21222.2 - 1.5e-20 73.6 0.0 2.3e-19 69.7 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 CBK21222.2 - 1.1e-09 38.5 0.0 1.9e-08 34.5 0.0 2.8 3 1 1 4 4 4 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 CBK21222.2 - 3.2e-09 36.4 0.1 7.7e-09 35.1 0.1 1.5 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 DEAD PF00270.29 CBK21222.2 - 2.5e-08 33.9 0.0 8.9e-08 32.1 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase ERCC3_RAD25_C PF16203.5 CBK21222.2 - 0.0057 15.9 0.0 0.0098 15.1 0.0 1.4 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase SWI2_SNF2 PF18766.1 CBK21222.2 - 0.011 15.4 0.0 0.087 12.5 0.0 2.2 2 0 0 2 2 2 0 SWI2/SNF2 ATPase SirA PF10747.9 CBK21222.2 - 0.3 11.4 3.1 0.27 11.6 0.3 2.3 3 0 0 3 3 3 0 Sporulation inhibitor of replication protein SirA Ribosomal_S26e PF01283.19 CBK21223.2 - 4.5e-44 149.3 6.9 5e-44 149.2 6.9 1.0 1 0 0 1 1 1 1 Ribosomal protein S26e Fer4_7 PF12838.7 CBK21223.2 - 0.00083 19.9 0.8 0.077 13.6 0.2 2.2 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_6 PF12837.7 CBK21223.2 - 0.0069 16.4 2.9 0.042 13.9 0.8 2.2 2 0 0 2 2 2 1 4Fe-4S binding domain SRP19 PF01922.17 CBK21223.2 - 0.0076 17.2 0.2 0.011 16.7 0.2 1.3 1 0 0 1 1 1 1 SRP19 protein RNA_pol_N PF01194.17 CBK21223.2 - 0.032 14.5 2.0 0.06 13.6 2.0 1.5 1 1 0 1 1 1 0 RNA polymerases N / 8 kDa subunit Fer4_2 PF12797.7 CBK21223.2 - 0.045 13.9 3.4 0.14 12.3 1.1 2.2 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4 PF00037.27 CBK21223.2 - 0.081 12.8 3.5 0.1 12.4 0.8 2.1 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_4 PF12800.7 CBK21223.2 - 0.89 10.2 7.3 0.64 10.7 2.6 2.2 2 0 0 2 2 2 0 4Fe-4S binding domain MAP65_ASE1 PF03999.12 CBK21224.2 - 3e-08 32.8 5.5 3.2e-08 32.7 5.5 1.0 1 0 0 1 1 1 1 Microtubule associated protein (MAP65/ASE1 family) FeoB_Cyto PF17910.1 CBK21224.2 - 0.014 15.9 1.5 0.064 13.8 0.2 2.1 1 1 1 2 2 2 0 FeoB cytosolic helical domain YkyA PF10368.9 CBK21224.2 - 0.58 9.8 7.2 1.3 8.6 7.2 1.5 1 1 0 1 1 1 0 Putative cell-wall binding lipoprotein MAP65_ASE1 PF03999.12 CBK21225.2 - 2.5e-17 62.8 23.8 5.2e-17 61.8 23.9 1.4 1 1 0 1 1 1 1 Microtubule associated protein (MAP65/ASE1 family) Baculo_PEP_C PF04513.12 CBK21225.2 - 0.0016 18.5 2.2 0.0016 18.5 2.2 2.9 2 1 1 3 3 3 1 Baculovirus polyhedron envelope protein, PEP, C terminus Fzo_mitofusin PF04799.13 CBK21225.2 - 0.043 13.4 0.5 0.043 13.4 0.5 3.3 2 1 2 4 4 4 0 fzo-like conserved region Cucumopine_C PF18631.1 CBK21225.2 - 0.068 13.1 0.1 0.2 11.6 0.1 1.9 1 1 0 1 1 1 0 Cucumopine synthase C-terminal helical bundle domain DUF4795 PF16043.5 CBK21225.2 - 0.093 12.3 16.5 0.33 10.5 3.0 2.4 1 1 0 2 2 2 0 Domain of unknown function (DUF4795) Atypical_Card PF18461.1 CBK21225.2 - 0.61 10.3 3.8 0.23 11.7 0.5 2.1 3 0 0 3 3 3 0 Atypical caspase recruitment domain MutS_III PF05192.18 CBK21225.2 - 0.76 10.0 8.5 1.1 9.4 3.4 2.1 2 0 0 2 2 2 0 MutS domain III OmpH PF03938.14 CBK21225.2 - 1.3 9.3 10.6 0.82 10.0 0.5 2.9 2 1 0 2 2 2 0 Outer membrane protein (OmpH-like) DUF896 PF05979.12 CBK21225.2 - 2 8.4 6.6 18 5.3 0.3 3.6 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF896) ATP-synt_C PF00137.21 CBK21226.2 - 1.3e-21 76.6 17.9 1.1e-13 51.2 10.7 2.3 2 0 0 2 2 2 2 ATP synthase subunit C HCV_NS4b PF01001.19 CBK21226.2 - 1.3 8.6 7.5 5.4 6.6 0.1 2.0 2 0 0 2 2 2 0 Hepatitis C virus non-structural protein NS4b SLATT_5 PF18160.1 CBK21226.2 - 3.5 6.9 6.7 1.4 8.2 0.4 2.4 1 1 1 3 3 3 0 SMODS and SLOG-associating 2TM effector domain family 5 YEATS PF03366.16 CBK21227.2 - 4.6e-29 100.2 0.1 6e-29 99.9 0.1 1.2 1 0 0 1 1 1 1 YEATS family Fe_hyd_SSU PF02256.17 CBK21227.2 - 0.044 13.9 0.2 0.079 13.1 0.2 1.4 1 0 0 1 1 1 0 Iron hydrogenase small subunit Cyclophil_like PF04126.13 CBK21227.2 - 0.12 12.2 0.0 0.19 11.6 0.0 1.3 1 0 0 1 1 1 0 Cyclophilin-like UCH PF00443.29 CBK21228.2 - 3.7e-45 154.4 0.0 4.5e-45 154.2 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 CBK21228.2 - 6.8e-09 35.8 0.2 2.2e-07 30.8 0.2 2.4 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Peptidase_C98 PF15499.6 CBK21228.2 - 0.11 12.0 0.0 0.38 10.2 0.0 1.8 2 0 0 2 2 2 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase DKCLD PF08068.12 CBK21229.2 - 9.4e-33 112.1 1.6 7.9e-32 109.1 0.5 2.7 3 0 0 3 3 3 1 DKCLD (NUC011) domain TruB_C_2 PF16198.5 CBK21229.2 - 1.7e-21 76.1 0.6 3.6e-21 75.1 0.6 1.6 1 0 0 1 1 1 1 tRNA pseudouridylate synthase B C-terminal domain PUA PF01472.20 CBK21229.2 - 3.4e-21 75.0 1.7 7.3e-21 73.9 1.7 1.6 1 0 0 1 1 1 1 PUA domain TruB_N PF01509.18 CBK21229.2 - 1.5e-20 74.1 6.9 2.6e-19 70.0 0.1 3.8 2 1 0 2 2 2 1 TruB family pseudouridylate synthase (N terminal domain) UPF0113 PF03657.13 CBK21229.2 - 0.00033 20.9 0.1 0.0014 18.9 0.0 2.1 2 0 0 2 2 2 1 UPF0113 PUA domain eIF_4EBP PF05456.11 CBK21229.2 - 0.47 10.4 7.6 1.1 9.3 7.6 1.6 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) DDHD PF02862.17 CBK21229.2 - 1.3 9.1 5.6 2.1 8.5 5.6 1.3 1 0 0 1 1 1 0 DDHD domain DUF913 PF06025.12 CBK21229.2 - 2 7.3 5.7 2.9 6.8 5.7 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) RNA_pol_Rpc4 PF05132.14 CBK21229.2 - 2.5 8.5 15.1 5.6 7.4 15.1 1.6 1 0 0 1 1 1 0 RNA polymerase III RPC4 RR_TM4-6 PF06459.12 CBK21229.2 - 5.9 6.6 22.9 8.9 6.1 22.9 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 14-3-3 PF00244.20 CBK21230.2 - 4.6e-87 291.2 1.9 5.2e-87 291.0 1.9 1.0 1 0 0 1 1 1 1 14-3-3 protein Peptidase_C50 PF03568.17 CBK21230.2 - 0.02 14.1 0.1 0.024 13.8 0.1 1.3 1 0 0 1 1 1 0 Peptidase family C50 FlaF PF07309.11 CBK21230.2 - 0.069 13.2 0.0 0.2 11.6 0.0 1.8 1 0 0 1 1 1 0 Flagellar protein FlaF ATG16 PF08614.11 CBK21231.2 - 0.00013 22.3 16.4 0.00016 22.0 16.4 1.1 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) Med14 PF08638.11 CBK21231.2 - 0.0043 16.5 0.8 0.0049 16.3 0.8 1.1 1 0 0 1 1 1 1 Mediator complex subunit MED14 DUF4201 PF13870.6 CBK21231.2 - 0.0063 16.3 10.5 0.0063 16.3 10.5 1.7 1 1 1 2 2 2 1 Domain of unknown function (DUF4201) Myosin_tail_1 PF01576.19 CBK21231.2 - 0.017 12.9 19.1 0.02 12.8 19.1 1.0 1 0 0 1 1 1 0 Myosin tail CCDC92 PF14916.6 CBK21231.2 - 0.028 14.2 1.6 0.028 14.2 1.6 1.9 2 0 0 2 2 2 0 Coiled-coil domain of unknown function V_ATPase_I PF01496.19 CBK21231.2 - 0.073 11.0 7.6 0.074 11.0 7.6 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Exonuc_VII_L PF02601.15 CBK21231.2 - 0.11 12.0 5.8 0.13 11.8 5.8 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit Spc7 PF08317.11 CBK21231.2 - 0.15 11.0 18.6 0.18 10.7 18.6 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein TSC22 PF01166.18 CBK21231.2 - 0.64 10.4 9.9 0.11 12.8 5.1 2.2 1 1 2 3 3 3 0 TSC-22/dip/bun family EMP24_GP25L PF01105.24 CBK21231.2 - 0.69 9.8 5.5 0.85 9.5 5.0 1.4 1 1 0 1 1 1 0 emp24/gp25L/p24 family/GOLD APG6_N PF17675.1 CBK21231.2 - 1.5 9.3 21.9 2 8.9 21.9 1.2 1 0 0 1 1 1 0 Apg6 coiled-coil region YabA PF06156.13 CBK21231.2 - 1.9 9.2 11.3 0.41 11.3 6.8 1.9 1 1 1 2 2 2 0 Initiation control protein YabA UPF0449 PF15136.6 CBK21231.2 - 2 8.9 14.1 7.5 7.1 1.4 2.3 1 1 1 2 2 2 0 Uncharacterised protein family UPF0449 DUF1664 PF07889.12 CBK21231.2 - 2.1 8.4 9.9 0.62 10.1 2.2 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DUF812 PF05667.11 CBK21231.2 - 3.9 6.2 16.8 4.8 6.0 16.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) KLRAQ PF10205.9 CBK21231.2 - 4.1 7.7 15.1 5 7.4 6.4 2.2 1 1 1 2 2 2 0 Predicted coiled-coil domain-containing protein Arm-DNA-bind_5 PF17293.2 CBK21231.2 - 4.3 7.8 10.7 39 4.8 10.7 2.3 1 1 0 1 1 1 0 Arm DNA-binding domain DHR10 PF18595.1 CBK21231.2 - 4.5 7.3 22.5 2.7 8.1 14.7 2.2 1 1 1 2 2 2 0 Designed helical repeat protein 10 domain TMPIT PF07851.13 CBK21231.2 - 4.9 6.3 10.9 6.4 5.9 10.9 1.2 1 0 0 1 1 1 0 TMPIT-like protein UPF0242 PF06785.11 CBK21231.2 - 5.5 7.0 18.1 9.5 6.3 18.1 1.4 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus MORN PF02493.20 CBK21232.2 - 0.0016 18.2 8.0 0.0042 16.9 0.3 4.5 6 0 0 6 6 6 1 MORN repeat MORN_2 PF07661.13 CBK21232.2 - 1.7 9.1 7.3 50 4.6 0.4 4.2 4 0 0 4 4 4 0 MORN repeat variant Ank_4 PF13637.6 CBK21234.2 - 1e-12 48.3 0.1 2.6e-07 31.0 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 CBK21234.2 - 1.2e-12 48.2 0.0 4.4e-12 46.4 0.0 1.9 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 CBK21234.2 - 9e-08 31.8 0.0 0.00056 20.2 0.1 2.7 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.6 CBK21234.2 - 0.00056 20.1 0.4 0.0041 17.4 0.4 2.2 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.30 CBK21234.2 - 0.0014 19.0 0.0 1 9.9 0.1 2.9 2 0 0 2 2 2 1 Ankyrin repeat Trypan_PARP PF05887.11 CBK21234.2 - 0.081 12.9 9.2 0.15 12.1 9.2 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) ALMT PF11744.8 CBK21234.2 - 1 8.1 4.3 1.7 7.4 4.3 1.4 1 0 0 1 1 1 0 Aluminium activated malate transporter Zip PF02535.22 CBK21234.2 - 1.5 8.0 11.3 2.3 7.4 11.3 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter Peptidase_S64 PF08192.11 CBK21234.2 - 6.2 5.2 13.7 8.7 4.7 13.7 1.1 1 0 0 1 1 1 0 Peptidase family S64 Presenilin PF01080.17 CBK21234.2 - 8.5 5.0 10.4 11 4.6 10.4 1.2 1 0 0 1 1 1 0 Presenilin Ribosomal_L11_N PF03946.14 CBK21235.2 - 4e-18 65.0 0.5 6.6e-18 64.3 0.5 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.19 CBK21235.2 - 2.9e-17 62.9 0.1 4.6e-17 62.3 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain DEAD PF00270.29 CBK21236.2 - 3.9e-22 78.8 0.0 1.8e-21 76.7 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CBK21236.2 - 6.1e-18 65.2 0.1 1.3e-17 64.1 0.1 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 CBK21236.2 - 1.8e-05 24.8 0.0 3.2e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Snf7 PF03357.21 CBK21236.2 - 0.059 13.0 0.4 0.098 12.2 0.4 1.2 1 0 0 1 1 1 0 Snf7 DNA_photolyase PF00875.18 CBK21236.2 - 0.11 12.5 0.2 0.22 11.5 0.2 1.5 1 0 0 1 1 1 0 DNA photolyase Yqai PF09466.10 CBK21236.2 - 0.16 12.3 0.0 7.7 6.9 0.0 2.4 2 0 0 2 2 2 0 Hypothetical protein Yqai Ribosomal_L13 PF00572.18 CBK21237.2 - 1.7e-35 122.0 0.4 1.7e-35 122.0 0.4 1.9 2 0 0 2 2 2 1 Ribosomal protein L13 Glycos_transf_1 PF00534.20 CBK21238.2 - 3.2e-32 111.4 0.0 5.2e-32 110.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 CBK21238.2 - 3.6e-15 56.6 0.0 5.8e-15 55.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 CBK21238.2 - 2.7e-14 53.5 0.0 5.8e-14 52.4 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_1_2 PF13524.6 CBK21238.2 - 5.7e-07 29.8 0.0 1.1e-06 28.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 CBK21238.2 - 7.3e-06 26.5 0.0 1.2e-05 25.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain ALG11_N PF15924.5 CBK21238.2 - 0.12 12.5 2.7 12 5.8 0.0 3.1 1 1 1 2 2 2 0 ALG11 mannosyltransferase N-terminus Pkinase PF00069.25 CBK21239.2 - 6.3e-49 166.7 0.0 9.3e-49 166.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Vps16_C PF04840.12 CBK21239.2 - 1.2e-24 86.9 0.4 1.8e-24 86.4 0.4 1.2 1 0 0 1 1 1 1 Vps16, C-terminal region Pkinase_Tyr PF07714.17 CBK21239.2 - 2.4e-09 36.9 0.0 5.3e-08 32.4 0.0 2.3 2 1 0 2 2 2 1 Protein tyrosine kinase APH PF01636.23 CBK21239.2 - 0.018 14.9 0.3 21 4.9 0.0 3.5 3 1 1 4 4 4 0 Phosphotransferase enzyme family Hemopexin PF00045.19 CBK21240.2 - 0.17 11.8 0.3 0.52 10.3 0.3 1.8 1 0 0 1 1 1 0 Hemopexin Prefoldin PF02996.17 CBK21241.2 - 1.3e-13 50.9 0.3 1.3e-13 50.9 0.3 1.1 1 0 0 1 1 1 1 Prefoldin subunit MORN PF02493.20 CBK21242.2 - 3.4e-21 73.8 50.3 8.3e-05 22.3 0.8 11.2 12 0 0 12 12 12 7 MORN repeat MORN_2 PF07661.13 CBK21242.2 - 4.8e-05 23.1 22.4 6.2 7.4 0.7 9.0 8 1 0 8 8 8 5 MORN repeat variant DEAD PF00270.29 CBK21243.2 - 7.4e-46 156.1 0.2 1.2e-45 155.5 0.2 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CBK21243.2 - 3.6e-30 104.6 0.2 5.2e-29 100.8 0.0 2.9 4 0 0 4 4 4 1 Helicase conserved C-terminal domain ResIII PF04851.15 CBK21243.2 - 4.6e-10 39.8 0.0 1.4e-09 38.2 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit SWI2_SNF2 PF18766.1 CBK21243.2 - 0.006 16.3 0.0 0.013 15.2 0.0 1.5 1 1 0 1 1 1 1 SWI2/SNF2 ATPase AAA_19 PF13245.6 CBK21243.2 - 0.024 15.0 0.0 0.077 13.3 0.0 1.8 1 1 0 1 1 1 0 AAA domain CMS1 PF14617.6 CBK21243.2 - 0.059 12.7 0.0 0.059 12.7 0.0 2.7 2 1 1 3 3 3 0 U3-containing 90S pre-ribosomal complex subunit AAA_lid_5 PF17865.1 CBK21243.2 - 0.077 13.1 0.0 0.26 11.4 0.0 1.9 2 0 0 2 2 2 0 Midasin AAA lid domain DUF563 PF04577.14 CBK21244.2 - 1.7e-17 64.3 1.3 2.5e-17 63.7 0.5 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF563) Pkinase PF00069.25 CBK21245.2 - 2.1e-115 384.6 0.0 4.7e-62 209.7 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CBK21245.2 - 3.2e-45 154.5 0.0 3.2e-23 82.3 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 CBK21245.2 - 1e-09 38.1 0.0 0.0013 18.1 0.0 2.4 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.14 CBK21245.2 - 2.6e-09 36.7 0.0 6.1e-05 22.5 0.0 2.3 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 CBK21245.2 - 1.1e-08 34.3 0.0 0.0012 17.7 0.0 2.2 2 0 0 2 2 2 2 Fungal protein kinase APH PF01636.23 CBK21245.2 - 9e-05 22.5 1.6 0.38 10.7 0.8 2.3 2 0 0 2 2 2 2 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.9 CBK21245.2 - 0.00052 19.6 0.1 0.22 11.0 0.0 2.4 2 0 0 2 2 2 2 PhoP regulatory network protein YrbL Pox_ser-thr_kin PF05445.11 CBK21245.2 - 0.00058 19.0 0.1 0.65 8.9 0.0 2.2 2 0 0 2 2 2 2 Poxvirus serine/threonine protein kinase RIO1 PF01163.22 CBK21245.2 - 0.011 15.4 0.1 0.82 9.2 0.0 2.4 2 0 0 2 2 2 0 RIO1 family FTA2 PF13095.6 CBK21245.2 - 0.011 15.4 0.1 5.3 6.6 0.0 2.5 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Choline_kinase PF01633.20 CBK21245.2 - 0.18 11.4 0.5 7 6.2 0.0 2.4 2 0 0 2 2 2 0 Choline/ethanolamine kinase DUF572 PF04502.13 CBK21246.2 - 5.8e-58 197.1 14.3 6.8e-58 196.9 14.3 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF572) zf-ribbon_3 PF13248.6 CBK21246.2 - 0.011 15.2 0.5 3.2 7.3 0.1 2.4 2 0 0 2 2 2 0 zinc-ribbon domain TF_Zn_Ribbon PF08271.12 CBK21246.2 - 0.022 14.2 2.4 0.05 13.1 0.1 2.3 2 0 0 2 2 2 0 TFIIB zinc-binding zf-FCS PF06467.14 CBK21246.2 - 0.064 13.2 0.6 12 5.9 0.1 2.4 2 0 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif GFA PF04828.14 CBK21246.2 - 0.083 13.2 1.0 0.96 9.8 0.1 2.4 1 1 0 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme Zn-ribbon_8 PF09723.10 CBK21246.2 - 0.085 13.0 1.2 6.1 7.0 0.2 2.6 2 0 0 2 2 2 0 Zinc ribbon domain DUF4887 PF16228.5 CBK21246.2 - 0.83 9.8 18.3 1.3 9.2 18.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4887) AAA_23 PF13476.6 CBK21246.2 - 1 9.8 15.3 2 8.9 15.3 1.5 1 0 0 1 1 1 0 AAA domain DUF501 PF04417.12 CBK21246.2 - 8.7 6.2 8.3 1.3 8.8 3.3 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF501) 6PF2K PF01591.18 CBK21247.2 - 3e-42 144.5 0.1 4e-42 144.0 0.1 1.2 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 CBK21247.2 - 4.4e-35 121.1 0.0 6.8e-35 120.5 0.0 1.3 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.6 CBK21247.2 - 9.4e-05 22.6 0.0 0.00058 20.0 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 CBK21247.2 - 0.00012 22.6 0.0 0.00025 21.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain PRK PF00485.18 CBK21247.2 - 0.0013 18.5 0.0 0.075 12.8 0.0 2.7 3 0 0 3 3 3 1 Phosphoribulokinase / Uridine kinase family Zeta_toxin PF06414.12 CBK21247.2 - 0.002 17.4 0.0 0.0049 16.2 0.0 1.6 1 0 0 1 1 1 1 Zeta toxin AAA_17 PF13207.6 CBK21247.2 - 0.006 17.0 0.0 0.013 15.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain SRP54 PF00448.22 CBK21247.2 - 0.0066 16.1 0.0 0.012 15.2 0.0 1.4 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain APS_kinase PF01583.20 CBK21247.2 - 0.007 16.3 0.0 0.013 15.4 0.0 1.4 1 0 0 1 1 1 1 Adenylylsulphate kinase NTPase_1 PF03266.15 CBK21247.2 - 0.015 15.2 0.1 0.062 13.2 0.0 2.0 2 0 0 2 2 2 0 NTPase AAA PF00004.29 CBK21247.2 - 0.018 15.5 0.0 0.051 14.0 0.0 1.8 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 CBK21247.2 - 0.043 13.9 0.2 0.15 12.1 0.0 2.1 2 1 0 2 2 2 0 AAA domain AAA_24 PF13479.6 CBK21247.2 - 0.05 13.3 0.0 0.28 10.9 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.14 CBK21247.2 - 0.059 13.4 0.0 0.13 12.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) NACHT PF05729.12 CBK21247.2 - 0.06 13.3 0.0 0.31 11.0 0.0 2.1 1 1 0 1 1 1 0 NACHT domain AAA_22 PF13401.6 CBK21247.2 - 0.12 12.7 0.0 0.28 11.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain MobB PF03205.14 CBK21247.2 - 0.2 11.5 0.0 0.39 10.6 0.0 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B PPI_Ypi1 PF07491.11 CBK21248.2 - 3.1e-23 81.4 3.1 4.4e-23 80.9 3.1 1.2 1 0 0 1 1 1 1 Protein phosphatase inhibitor MCM PF00493.23 CBK21249.2 - 1.3e-70 237.0 0.0 1.9e-70 236.5 0.0 1.2 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 CBK21249.2 - 5e-20 71.6 4.1 8.5e-20 70.9 4.1 1.3 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 CBK21249.2 - 2.7e-16 59.8 1.4 4.7e-16 59.0 1.4 1.4 1 0 0 1 1 1 1 MCM AAA-lid domain Mg_chelatase PF01078.21 CBK21249.2 - 0.0012 18.3 0.0 0.013 14.9 0.0 2.3 2 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 CBK21249.2 - 0.0037 17.3 0.0 0.0076 16.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Sars6 PF12133.8 CBK21249.2 - 0.098 12.6 0.0 0.19 11.7 0.0 1.4 1 0 0 1 1 1 0 Open reading frame 6 from SARS coronavirus AAA_3 PF07726.11 CBK21249.2 - 0.14 12.0 0.0 0.3 11.0 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Asp PF00026.23 CBK21250.2 - 6.2e-27 94.8 0.0 8e-27 94.5 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.6 CBK21250.2 - 0.00049 19.9 0.0 0.00075 19.3 0.0 1.2 1 0 0 1 1 1 1 Xylanase inhibitor C-terminal TAXi_N PF14543.6 CBK21250.2 - 0.00063 20.0 0.0 0.0012 19.1 0.0 1.4 1 0 0 1 1 1 1 Xylanase inhibitor N-terminal RNA_POL_M_15KD PF02150.16 CBK21251.2 - 6.5e-09 35.5 2.8 6.5e-09 35.5 2.8 2.5 3 0 0 3 3 3 1 RNA polymerases M/15 Kd subunit TFIIS_C PF01096.18 CBK21251.2 - 2.5e-07 30.4 2.9 2.5e-07 30.4 2.9 3.5 4 0 0 4 4 4 2 Transcription factor S-II (TFIIS) GFA PF04828.14 CBK21251.2 - 0.15 12.4 0.3 0.15 12.4 0.3 2.6 1 1 2 3 3 3 0 Glutathione-dependent formaldehyde-activating enzyme Rpr2 PF04032.16 CBK21251.2 - 0.69 10.2 9.0 3.5 8.0 9.0 2.3 1 1 0 1 1 1 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain RecR PF02132.15 CBK21251.2 - 3.3 7.4 13.1 0.99 9.0 0.1 3.8 4 0 0 4 4 4 0 RecR protein zf-H2C2_2 PF13465.6 CBK21251.2 - 3.9 8.1 0.0 3.9 8.1 0.0 3.7 4 0 0 4 4 4 0 Zinc-finger double domain HSP70 PF00012.20 CBK21252.2 - 7.7e-57 192.8 0.1 1.2e-56 192.2 0.1 1.2 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 CBK21252.2 - 2.7e-12 46.2 0.0 4.9e-07 28.9 0.0 3.1 3 0 0 3 3 3 3 MreB/Mbl protein P-mevalo_kinase PF04275.14 CBK21252.2 - 0.059 13.3 0.2 0.15 12.0 0.2 1.7 1 0 0 1 1 1 0 Phosphomevalonate kinase Topo_Zn_Ribbon PF08272.11 CBK21252.2 - 0.094 12.4 0.0 0.23 11.2 0.0 1.7 1 0 0 1 1 1 0 Topoisomerase I zinc-ribbon-like DDR PF08841.10 CBK21252.2 - 0.17 10.8 0.2 28 3.5 0.0 3.1 3 0 0 3 3 3 0 Diol dehydratase reactivase ATPase-like domain Hydantoinase_A PF01968.18 CBK21252.2 - 0.21 10.8 0.1 8.2 5.6 0.0 2.5 2 0 0 2 2 2 0 Hydantoinase/oxoprolinase HSP70 PF00012.20 CBK21253.2 - 3.8e-45 154.2 0.2 4.9e-45 153.8 0.2 1.1 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 CBK21253.2 - 1.8e-13 50.0 0.1 1.1e-09 37.6 0.1 3.7 2 1 0 2 2 2 2 MreB/Mbl protein StbA PF06406.11 CBK21253.2 - 0.0004 19.7 0.4 0.15 11.3 0.1 2.3 2 0 0 2 2 2 2 StbA protein DUF4379 PF14311.6 CBK21254.2 - 1.3e-19 70.3 10.9 2.7e-09 37.2 0.5 2.5 2 0 0 2 2 2 2 Probable Zinc-ribbon domain FANCL_C PF11793.8 CBK21254.2 - 0.0041 17.3 2.4 0.096 12.9 0.1 2.7 3 0 0 3 3 3 1 FANCL C-terminal domain zf-Di19 PF05605.12 CBK21254.2 - 5.3 7.4 7.0 22 5.5 0.3 3.1 3 0 0 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding Glyco_transf_49 PF13896.6 CBK21255.2 - 6.2e-17 61.9 0.1 1e-15 57.9 0.1 2.2 1 1 0 1 1 1 1 Glycosyl-transferase for dystroglycan Prothymosin PF03247.14 CBK21255.2 - 0.19 12.2 14.7 0.28 11.7 14.7 1.2 1 0 0 1 1 1 0 Prothymosin/parathymosin family Tim54 PF11711.8 CBK21255.2 - 0.38 9.5 2.6 0.55 9.0 2.6 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Ribosomal_60s PF00428.19 CBK21255.2 - 4.5 7.9 16.5 8.6 7.0 16.5 1.4 1 0 0 1 1 1 0 60s Acidic ribosomal protein FancD2 PF14631.6 CBK21255.2 - 8.3 3.7 5.7 11 3.2 5.7 1.1 1 0 0 1 1 1 0 Fanconi anaemia protein FancD2 nuclease Glyco_transf_24 PF18404.1 CBK21256.2 - 5.4e-126 419.5 5.7 1.1e-125 418.5 5.7 1.5 1 0 0 1 1 1 1 Glucosyltransferase 24 UDP-g_GGTase PF06427.11 CBK21256.2 - 1.4e-11 44.5 0.0 3.7e-11 43.1 0.0 1.8 1 1 1 2 2 2 1 UDP-glucose:Glycoprotein Glucosyltransferase Glyco_transf_8 PF01501.20 CBK21256.2 - 1.5e-05 24.7 0.8 3e-05 23.7 0.8 1.6 1 0 0 1 1 1 1 Glycosyl transferase family 8 CENP-B_dimeris PF09026.10 CBK21256.2 - 0.019 15.4 0.7 0.019 15.4 0.7 1.9 3 0 0 3 3 3 0 Centromere protein B dimerisation domain 6PGD PF00393.19 CBK21257.2 - 1.5e-58 198.4 0.0 2.1e-58 198.0 0.0 1.1 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.15 CBK21257.2 - 1.2e-24 87.3 0.0 2e-24 86.6 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase IlvN PF07991.12 CBK21257.2 - 0.0067 16.0 0.0 0.013 15.1 0.0 1.4 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain Peptidase_M14 PF00246.24 CBK21258.2 - 1.3e-22 80.9 0.0 1.8e-22 80.5 0.0 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase NtCtMGAM_N PF16863.5 CBK21258.2 - 0.0043 17.2 0.0 0.0083 16.3 0.0 1.4 1 0 0 1 1 1 1 N-terminal barrel of NtMGAM and CtMGAM, maltase-glucoamylase Proteasome PF00227.26 CBK21260.2 - 4.1e-46 156.9 0.3 5.6e-46 156.4 0.3 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 CBK21260.2 - 4.8e-14 51.7 0.1 8.2e-14 51.0 0.1 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature DNA_pol_B_2 PF03175.13 CBK21261.2 - 1.9e-17 63.3 9.5 9e-15 54.5 3.3 2.4 2 1 0 2 2 2 2 DNA polymerase type B, organellar and viral UTRA PF07702.13 CBK21261.2 - 0.18 11.6 0.0 0.35 10.7 0.0 1.4 1 0 0 1 1 1 0 UTRA domain bZIP_1 PF00170.21 CBK21262.2 - 7.3e-09 35.6 18.8 1.3e-08 34.8 18.8 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 CBK21262.2 - 2.1e-07 30.9 18.0 2.1e-07 30.9 18.0 2.1 3 0 0 3 3 3 1 Basic region leucine zipper bZIP_Maf PF03131.17 CBK21262.2 - 0.00018 21.9 16.1 0.00024 21.6 15.3 1.6 1 1 0 1 1 1 1 bZIP Maf transcription factor Atg14 PF10186.9 CBK21262.2 - 0.088 11.9 10.4 0.12 11.4 10.4 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Tho2 PF11262.8 CBK21262.2 - 0.62 9.2 6.3 0.87 8.7 6.3 1.1 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 DivIC PF04977.15 CBK21262.2 - 5.6 6.8 9.4 2.1 8.2 6.1 2.0 1 1 1 2 2 2 0 Septum formation initiator DUF2130 PF09903.9 CBK21263.2 - 0.11 11.8 1.6 0.21 10.8 1.6 1.5 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2130) ETC_C1_NDUFA5 PF04716.14 CBK21264.2 - 4.2e-26 90.5 0.2 6.4e-26 90.0 0.2 1.3 1 0 0 1 1 1 1 ETC complex I subunit conserved region Phage_int_SAM_1 PF02899.17 CBK21264.2 - 0.017 15.4 0.0 0.03 14.6 0.0 1.4 1 1 0 1 1 1 0 Phage integrase, N-terminal SAM-like domain Rtt106_N PF18215.1 CBK21264.2 - 0.037 13.8 0.0 0.29 10.9 0.0 2.1 2 0 0 2 2 2 0 Histone chaperone Rtt106 N-terminal domain REV1_C PF16727.5 CBK21264.2 - 0.12 12.7 0.0 0.16 12.4 0.0 1.3 1 0 0 1 1 1 0 DNA repair protein REV1 C-terminal domain He_PIG PF05345.12 CBK21265.2 - 4.9e-06 26.6 0.5 0.018 15.2 1.6 2.6 2 0 0 2 2 2 2 Putative Ig domain Striatin PF08232.12 CBK21265.2 - 3.9 8.0 9.6 0.44 11.1 4.2 1.9 2 0 0 2 2 2 0 Striatin family RNA_pol_L_2 PF13656.6 CBK21266.2 - 1.2e-15 57.0 0.0 1.7e-15 56.5 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain YdaS_antitoxin PF15943.5 CBK21266.2 - 0.0016 18.3 0.0 0.0026 17.6 0.0 1.3 1 0 0 1 1 1 1 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT RNA_pol_L PF01193.24 CBK21266.2 - 0.016 14.7 0.0 0.02 14.3 0.0 1.3 1 0 0 1 1 1 0 RNA polymerase Rpb3/Rpb11 dimerisation domain DUF2097 PF09870.9 CBK21266.2 - 0.042 14.1 0.2 0.058 13.6 0.2 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2097) Rio2_N PF09202.11 CBK21266.2 - 0.05 13.8 0.0 0.095 12.9 0.0 1.4 1 0 0 1 1 1 0 Rio2, N-terminal PTPLA PF04387.14 CBK21267.2 - 3.1e-57 192.9 14.4 3.1e-57 192.9 14.4 1.5 2 0 0 2 2 2 1 Protein tyrosine phosphatase-like protein, PTPLA DUF2070 PF09843.9 CBK21267.2 - 0.68 8.2 4.1 0.82 7.9 4.1 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Actin PF00022.19 CBK21268.2 - 1.6e-23 83.0 0.0 1.9e-23 82.7 0.0 1.1 1 0 0 1 1 1 1 Actin Copine PF07002.16 CBK21269.2 - 5.7e-67 225.4 0.0 1.2e-66 224.4 0.0 1.5 2 0 0 2 2 2 1 Copine C2 PF00168.30 CBK21269.2 - 1.4e-11 44.5 0.1 3e-11 43.5 0.1 1.5 1 0 0 1 1 1 1 C2 domain vWA-TerF-like PF10138.9 CBK21269.2 - 1e-06 29.0 0.0 5.6e-06 26.6 0.0 1.9 2 0 0 2 2 2 1 vWA found in TerF C terminus VWA PF00092.28 CBK21269.2 - 0.011 16.0 0.0 0.02 15.2 0.0 1.3 1 0 0 1 1 1 0 von Willebrand factor type A domain GCV_H PF01597.19 CBK21270.2 - 3.5e-42 143.1 0.0 4.3e-42 142.8 0.0 1.1 1 0 0 1 1 1 1 Glycine cleavage H-protein Biotin_lipoyl PF00364.22 CBK21270.2 - 0.079 12.8 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 Biotin-requiring enzyme Ribosomal_S8e PF01201.22 CBK21271.2 - 3.4e-35 121.2 0.1 4.4e-35 120.8 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein S8e zf-RING_4 PF14570.6 CBK21272.2 - 2e-16 59.5 14.8 5.5e-16 58.1 14.8 1.8 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-C3HC4_3 PF13920.6 CBK21272.2 - 1.1e-05 25.2 14.7 2.6e-05 24.0 14.7 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) RRM_1 PF00076.22 CBK21272.2 - 0.00018 21.2 0.0 0.00035 20.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-C3H1 PF10650.9 CBK21272.2 - 0.0041 16.8 0.6 0.0099 15.6 0.1 2.0 2 0 0 2 2 2 1 Putative zinc-finger domain Rtf2 PF04641.12 CBK21272.2 - 0.013 14.9 8.1 0.025 14.0 8.1 1.4 1 1 0 1 1 1 0 Rtf2 RING-finger zf-RING_2 PF13639.6 CBK21272.2 - 0.013 15.8 18.5 0.05 13.9 18.5 2.1 1 0 0 1 1 1 0 Ring finger domain Torus PF16131.5 CBK21272.2 - 0.014 16.0 0.9 0.014 16.0 0.9 2.1 2 0 0 2 2 2 0 Torus domain Rad50_zn_hook PF04423.14 CBK21272.2 - 0.033 14.0 0.7 0.033 14.0 0.7 2.3 2 0 0 2 2 2 0 Rad50 zinc hook motif zinc_ribbon_2 PF13240.6 CBK21272.2 - 0.049 13.4 9.3 0.098 12.4 0.4 3.1 3 0 0 3 3 3 0 zinc-ribbon domain RFX_DNA_binding PF02257.15 CBK21272.2 - 0.18 12.5 1.4 2.5 8.8 0.9 2.4 1 1 0 2 2 2 0 RFX DNA-binding domain DUF1272 PF06906.11 CBK21272.2 - 1.8 8.7 14.7 4.5 7.4 14.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) Rad51 PF08423.11 CBK21274.2 - 1.6e-114 381.5 0.2 2e-114 381.2 0.2 1.1 1 0 0 1 1 1 1 Rad51 RecA PF00154.21 CBK21274.2 - 9.4e-13 48.2 0.4 1.2e-12 47.9 0.4 1.1 1 0 0 1 1 1 1 recA bacterial DNA recombination protein AAA_25 PF13481.6 CBK21274.2 - 3.5e-10 39.8 0.1 5.7e-10 39.1 0.1 1.2 1 0 0 1 1 1 1 AAA domain ATPase PF06745.13 CBK21274.2 - 1e-06 28.3 0.4 2.5e-06 27.0 0.4 1.7 1 1 0 1 1 1 1 KaiC AAA_24 PF13479.6 CBK21274.2 - 1.8e-05 24.5 0.0 4.7e-05 23.2 0.0 1.7 1 1 0 1 1 1 1 AAA domain DnaB_C PF03796.15 CBK21274.2 - 0.00012 21.5 0.7 0.0025 17.2 0.0 2.4 3 0 0 3 3 3 1 DnaB-like helicase C terminal domain Translat_reg PF01818.17 CBK21274.2 - 0.04 13.9 0.0 0.076 13.0 0.0 1.4 1 0 0 1 1 1 0 Bacteriophage translational regulator AAA_22 PF13401.6 CBK21274.2 - 0.085 13.1 0.1 0.15 12.4 0.1 1.3 1 0 0 1 1 1 0 AAA domain Actin PF00022.19 CBK21275.2 - 1.5e-89 300.4 0.0 1.7e-89 300.3 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.13 CBK21275.2 - 0.0043 15.9 0.0 0.38 9.5 0.0 2.4 2 0 0 2 2 2 2 MreB/Mbl protein COMM_domain PF07258.14 CBK21277.2 - 5.5e-06 26.4 0.8 9e-06 25.7 0.8 1.3 1 0 0 1 1 1 1 COMM domain SAICAR_synt PF01259.18 CBK21278.2 - 1.8e-75 253.8 0.0 2.4e-75 253.4 0.0 1.2 1 0 0 1 1 1 1 SAICAR synthetase AIRC PF00731.20 CBK21278.2 - 5.6e-40 136.3 0.1 8.8e-40 135.7 0.1 1.3 1 0 0 1 1 1 1 AIR carboxylase Utp13 PF08625.11 CBK21279.2 - 0.23 11.4 0.0 0.28 11.1 0.0 1.2 1 0 0 1 1 1 0 Utp13 specific WD40 associated domain Ribosomal_L5_C PF00673.21 CBK21280.2 - 1.5e-20 73.1 0.0 2.4e-20 72.5 0.0 1.3 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.19 CBK21280.2 - 1.9e-18 66.5 0.3 3.8e-18 65.6 0.1 1.6 2 0 0 2 2 2 1 Ribosomal protein L5 HTH_ABP1_N PF18107.1 CBK21280.2 - 0.013 15.2 0.4 0.071 12.8 0.1 2.0 2 0 0 2 2 2 0 Fission yeast centromere protein N-terminal domain Rotamase PF00639.21 CBK21281.2 - 3.7e-19 69.5 0.0 5.2e-19 69.0 0.0 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_3 PF13616.6 CBK21281.2 - 1.5e-16 61.0 0.0 1.9e-16 60.6 0.0 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_2 PF13145.6 CBK21281.2 - 8.7e-05 23.3 0.0 0.00043 21.1 0.0 1.8 2 0 0 2 2 2 1 PPIC-type PPIASE domain MMR_HSR1 PF01926.23 CBK21282.2 - 0.04 14.0 0.0 0.059 13.5 0.0 1.2 1 0 0 1 1 1 0 50S ribosome-binding GTPase Ribosomal_60s PF00428.19 CBK21283.2 - 9.9e-23 80.6 16.2 1.1e-22 80.3 16.2 1.0 1 0 0 1 1 1 1 60s Acidic ribosomal protein RNA_pol_3_Rpc31 PF11705.8 CBK21283.2 - 1.6 8.9 8.7 2.1 8.6 8.7 1.1 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 RNA_pol_Rpb5_C PF01191.19 CBK21284.2 - 8.1e-26 89.7 0.2 1.9e-25 88.5 0.0 1.7 2 0 0 2 2 2 1 RNA polymerase Rpb5, C-terminal domain RNA_pol_Rpb5_N PF03871.14 CBK21284.2 - 9e-10 39.0 0.0 1.4e-09 38.3 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb5, N-terminal domain Mrr_cat PF04471.12 CBK21284.2 - 0.056 13.5 0.0 0.078 13.0 0.0 1.4 1 1 0 1 1 1 0 Restriction endonuclease Pkinase PF00069.25 CBK21285.2 - 1.1e-23 83.9 0.0 1.7e-23 83.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBK21285.2 - 2e-10 40.4 0.0 5.3e-10 39.0 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.23 CBK21285.2 - 0.033 14.1 0.0 0.053 13.4 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kinase-like PF14531.6 CBK21285.2 - 0.048 13.0 0.0 0.12 11.7 0.0 1.6 2 0 0 2 2 2 0 Kinase-like FAM220 PF15487.6 CBK21285.2 - 0.15 11.7 1.0 7.4 6.1 0.3 2.2 2 0 0 2 2 2 0 FAM220 family Seadorna_VP7 PF07387.11 CBK21285.2 - 0.2 10.7 0.0 0.34 9.9 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 Cyclin_N PF00134.23 CBK21286.2 - 5.6e-32 110.2 1.0 9.3e-32 109.4 1.0 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Mito_fiss_reg PF05308.11 CBK21287.2 - 0.13 12.3 0.3 0.16 12.0 0.3 1.1 1 0 0 1 1 1 0 Mitochondrial fission regulator CAP_N PF01213.19 CBK21287.2 - 0.55 9.7 4.9 0.72 9.3 4.9 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal PRIMA1 PF16101.5 CBK21287.2 - 5.6 7.0 10.9 9.3 6.3 10.9 1.4 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 DUF2417 PF10329.9 CBK21288.2 - 0.024 14.1 0.4 0.024 14.1 0.4 1.1 1 0 0 1 1 1 0 Region of unknown function (DUF2417) Hist_deacetyl PF00850.19 CBK21289.2 - 8.6e-81 271.8 0.0 1.2e-80 271.3 0.0 1.2 1 0 0 1 1 1 1 Histone deacetylase domain Colicin_immun PF09204.10 CBK21289.2 - 0.032 14.8 1.3 0.79 10.3 0.0 2.7 3 0 0 3 3 3 0 Bacterial self-protective colicin-like immunity MA3 PF02847.17 CBK21290.2 - 1.2e-17 63.9 1.6 1.7e-16 60.2 0.4 2.5 2 1 0 2 2 2 1 MA3 domain Na_trans_assoc PF06512.13 CBK21290.2 - 0.046 14.0 6.2 0.085 13.1 6.2 1.5 1 0 0 1 1 1 0 Sodium ion transport-associated DUF5523 PF17661.1 CBK21290.2 - 0.19 11.4 10.8 0.32 10.6 10.8 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5523) RRN3 PF05327.11 CBK21290.2 - 0.23 10.0 8.7 0.42 9.1 8.7 1.4 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Radial_spoke PF04712.12 CBK21290.2 - 0.38 9.7 7.4 0.54 9.1 7.4 1.4 1 0 0 1 1 1 0 Radial spokehead-like protein FAM176 PF14851.6 CBK21290.2 - 0.38 10.4 5.2 0.94 9.1 5.2 1.7 1 0 0 1 1 1 0 FAM176 family PBP1_TM PF14812.6 CBK21290.2 - 0.45 10.9 10.8 0.89 10.0 10.8 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal RPN2_C PF18004.1 CBK21290.2 - 0.72 9.8 4.7 1.2 9.0 4.7 1.3 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain DUF4637 PF15470.6 CBK21290.2 - 0.94 9.2 8.4 1.7 8.3 8.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) CDC45 PF02724.14 CBK21290.2 - 1.1 7.5 13.1 1.6 6.9 13.1 1.2 1 0 0 1 1 1 0 CDC45-like protein NOA36 PF06524.12 CBK21290.2 - 1.2 8.4 17.8 2.4 7.4 17.8 1.4 1 0 0 1 1 1 0 NOA36 protein TLP-20 PF06088.11 CBK21290.2 - 1.4 8.7 8.7 2.4 8.0 8.7 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) BUD22 PF09073.10 CBK21290.2 - 1.8 7.9 11.2 2.4 7.4 11.2 1.1 1 0 0 1 1 1 0 BUD22 DNA_pol_phi PF04931.13 CBK21290.2 - 2.2 6.3 25.7 1.7 6.6 20.7 2.2 2 0 0 2 2 2 0 DNA polymerase phi SDA1 PF05285.12 CBK21290.2 - 2.3 7.6 15.4 3.3 7.0 15.4 1.2 1 0 0 1 1 1 0 SDA1 CENP-B_dimeris PF09026.10 CBK21290.2 - 3.1 8.2 23.4 7.1 7.1 23.4 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain DUF2457 PF10446.9 CBK21290.2 - 6.2 5.8 23.6 9.3 5.3 23.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Sua5_yciO_yrdC PF01300.18 CBK21291.2 - 6.5e-49 165.9 0.0 1e-48 165.2 0.0 1.3 1 0 0 1 1 1 1 Telomere recombination SUA5 PF03481.13 CBK21291.2 - 1.1e-14 55.2 0.0 1.6e-14 54.6 0.0 1.3 1 0 0 1 1 1 1 Putative GTP-binding controlling metal-binding GAPES1 PF17155.4 CBK21291.2 - 0.27 10.5 0.0 0.42 9.9 0.0 1.2 1 0 0 1 1 1 0 Gammaproteobacterial periplasmic sensor domain DNA_pol_B_2 PF03175.13 CBK21292.2 - 4.3e-16 58.8 7.4 8e-16 57.9 7.4 1.5 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral HSP20 PF00011.21 CBK21293.2 - 3.2e-27 94.7 2.7 3.8e-27 94.4 2.7 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 CBK21293.2 - 3e-13 49.1 0.0 5e-13 48.4 0.0 1.4 1 0 0 1 1 1 1 HSP20-like domain found in ArsA Radical_SAM PF04055.21 CBK21294.2 - 8.6e-26 91.3 0.3 5.4e-25 88.7 0.2 2.0 2 0 0 2 2 2 1 Radical SAM superfamily IBN_N PF03810.19 CBK21296.2 - 1.6e-06 27.9 0.0 5.2e-06 26.3 0.0 1.9 2 0 0 2 2 2 1 Importin-beta N-terminal domain Adaptin_N PF01602.20 CBK21296.2 - 4e-05 22.4 0.1 0.00012 20.8 0.1 1.5 1 1 0 1 1 1 1 Adaptin N terminal region ParcG PF10274.9 CBK21296.2 - 0.11 12.6 0.1 3 7.9 0.0 2.2 2 0 0 2 2 2 0 Parkin co-regulated protein Vps35 PF03635.17 CBK21297.2 - 4e-12 45.5 0.3 4.5e-12 45.3 0.3 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 35 Vps35 PF03635.17 CBK21298.2 - 1.8e-82 278.1 5.4 2.5e-82 277.6 5.4 1.3 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 35 RabGAP-TBC PF00566.18 CBK21299.2 - 2e-20 73.4 0.0 2.5e-20 73.0 0.0 1.1 1 0 0 1 1 1 1 Rab-GTPase-TBC domain CTD_bind PF04818.13 CBK21299.2 - 0.018 15.9 0.1 0.039 14.8 0.1 1.6 1 1 0 1 1 1 0 RNA polymerase II-binding domain. MORN PF02493.20 CBK21300.2 - 5.4e-05 22.9 9.8 0.021 14.7 0.8 3.1 3 0 0 3 3 3 2 MORN repeat BtrH_N PF14399.6 CBK21300.2 - 0.14 12.4 0.0 0.24 11.6 0.0 1.3 1 0 0 1 1 1 0 Butirosin biosynthesis protein H, N-terminal MORN_2 PF07661.13 CBK21300.2 - 0.14 12.4 4.5 23 5.6 0.2 3.8 3 0 0 3 3 3 0 MORN repeat variant MORN PF02493.20 CBK21301.2 - 0.016 15.1 27.5 2.5 8.1 1.1 8.5 7 0 0 7 7 7 0 MORN repeat Slu7 PF11708.8 CBK21304.2 - 1.6e-51 175.6 4.8 3.1e-51 174.7 4.8 1.4 1 1 0 1 1 1 1 Pre-mRNA splicing Prp18-interacting factor DUF2031 PF09592.10 CBK21304.2 - 0.062 12.8 0.2 0.084 12.4 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2031) HORMA PF02301.18 CBK21305.2 - 2e-22 79.8 0.2 3e-22 79.3 0.2 1.2 1 0 0 1 1 1 1 HORMA domain bacHORMA_2 PF18173.1 CBK21305.2 - 3.3e-05 23.8 0.1 7.6e-05 22.6 0.1 1.6 2 0 0 2 2 2 1 Bacterial HORMA domain 2 ATG101 PF07855.12 CBK21305.2 - 0.0027 17.7 0.0 0.042 13.8 0.0 2.1 1 1 0 1 1 1 1 Autophagy-related protein 101 Neur_chan_LBD PF02931.23 CBK21305.2 - 0.0046 16.4 0.1 0.0073 15.8 0.1 1.3 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain ATG13 PF10033.9 CBK21305.2 - 0.0092 15.7 0.1 0.028 14.1 0.0 1.7 2 0 0 2 2 2 1 Autophagy-related protein 13 SRP40_C PF05022.12 CBK21306.2 - 8.8e-25 87.4 2.2 9.7e-24 84.0 2.2 3.0 1 0 0 1 1 1 1 SRP40, C-terminal domain B56 PF01603.20 CBK21307.2 - 1.3e-25 90.3 2.5 1.4e-25 90.1 2.5 1.0 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) B56 PF01603.20 CBK21308.2 - 2.1e-14 53.4 0.0 2.5e-14 53.1 0.0 1.0 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) Asparaginase PF00710.20 CBK21309.2 - 7.7e-48 162.6 0.0 1.4e-47 161.7 0.0 1.4 2 0 0 2 2 2 1 Asparaginase, N-terminal Asparaginase_C PF17763.1 CBK21309.2 - 1.3e-22 80.1 0.0 3.1e-22 79.0 0.0 1.6 2 0 0 2 2 2 1 Glutaminase/Asparaginase C-terminal domain GPI PF06560.11 CBK21309.2 - 0.081 12.2 0.1 0.28 10.4 0.0 1.8 2 0 0 2 2 2 0 Glucose-6-phosphate isomerase (GPI) Radical_SAM PF04055.21 CBK21310.2 - 1.2e-28 100.6 0.2 2.7e-28 99.4 0.2 1.7 1 0 0 1 1 1 1 Radical SAM superfamily UPF0004 PF00919.20 CBK21310.2 - 2e-20 72.6 0.6 3.8e-20 71.7 0.6 1.5 1 0 0 1 1 1 1 Uncharacterized protein family UPF0004 TRAM PF01938.20 CBK21310.2 - 0.00032 20.6 0.0 0.001 19.0 0.0 1.8 1 1 0 1 1 1 1 TRAM domain TRAM_LAG1_CLN8 PF03798.16 CBK21311.2 - 2.3e-26 92.8 25.5 2.3e-26 92.8 25.5 2.5 1 1 1 2 2 2 1 TLC domain TRAM1 PF08390.11 CBK21311.2 - 3.6e-09 36.2 0.3 3.6e-09 36.2 0.3 3.3 3 0 0 3 3 3 1 TRAM1-like protein WD40 PF00400.32 CBK21312.2 - 4.3e-07 30.5 1.0 0.056 14.3 0.1 3.3 3 0 0 3 3 3 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBK21312.2 - 4.5e-07 30.1 0.2 0.0027 18.0 0.1 3.0 1 1 2 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain IKI3 PF04762.12 CBK21312.2 - 0.00019 19.6 0.0 0.0022 16.1 0.1 1.9 1 1 1 2 2 2 2 IKI3 family WD40_like PF17005.5 CBK21312.2 - 0.014 14.8 0.0 0.018 14.4 0.0 1.2 1 0 0 1 1 1 0 WD40-like domain Nup160 PF11715.8 CBK21312.2 - 0.018 13.7 0.1 0.021 13.5 0.1 1.1 1 0 0 1 1 1 0 Nucleoporin Nup120/160 DUF5640 PF18692.1 CBK21312.2 - 0.14 12.2 0.0 0.28 11.2 0.0 1.5 1 1 0 1 1 1 0 Family of unknown function (DUF5640) NARP1 PF12569.8 CBK21313.2 - 8.9e-90 302.0 0.5 2.7e-85 287.2 0.0 2.4 1 1 1 2 2 2 2 NMDA receptor-regulated protein 1 TPR_19 PF14559.6 CBK21313.2 - 2.7e-07 31.0 9.2 0.024 15.1 0.0 5.6 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_2 PF07719.17 CBK21313.2 - 6.4e-06 25.9 9.2 0.48 10.7 0.1 5.6 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_1 PF00515.28 CBK21313.2 - 8.1e-05 22.3 1.9 0.25 11.2 0.0 4.7 4 0 0 4 4 4 1 Tetratricopeptide repeat ANAPC3 PF12895.7 CBK21313.2 - 0.00089 19.4 2.9 0.81 10.0 0.0 4.3 3 1 0 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.6 CBK21313.2 - 0.0017 19.0 9.6 1.3 9.7 0.2 5.7 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_14 PF13428.6 CBK21313.2 - 0.0024 18.5 15.5 1.1 10.2 1.2 6.4 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_7 PF13176.6 CBK21313.2 - 0.0031 17.4 3.2 0.34 11.1 0.2 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.6 CBK21313.2 - 0.01 15.9 2.5 0.11 12.7 0.2 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.6 CBK21313.2 - 0.02 15.2 2.6 2 8.8 0.4 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat Clathrin PF00637.20 CBK21314.2 - 8.5e-20 71.1 5.4 1e-17 64.3 0.2 3.4 3 0 0 3 3 3 2 Region in Clathrin and VPS Vps39_2 PF10367.9 CBK21314.2 - 5.1e-10 39.8 3.7 8.2e-09 35.9 0.4 2.8 3 0 0 3 3 3 1 Vacuolar sorting protein 39 domain 2 zf-RING_UBOX PF13445.6 CBK21314.2 - 0.0071 16.4 8.9 0.021 14.8 7.9 2.3 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_11 PF17123.5 CBK21314.2 - 0.055 13.2 5.4 0.18 11.6 5.4 1.9 1 0 0 1 1 1 0 RING-like zinc finger zf-RING_2 PF13639.6 CBK21314.2 - 0.22 11.9 9.0 0.53 10.7 9.0 1.7 1 0 0 1 1 1 0 Ring finger domain zf-C3H2C3 PF17122.5 CBK21314.2 - 0.34 11.0 7.5 0.56 10.3 5.9 2.2 2 0 0 2 2 2 0 Zinc-finger zf-rbx1 PF12678.7 CBK21314.2 - 5.2 7.4 9.9 1.9 8.9 6.2 2.1 2 0 0 2 2 2 0 RING-H2 zinc finger domain DHC_N1 PF08385.12 CBK21315.2 - 0.0021 16.8 0.0 0.0027 16.4 0.0 1.1 1 0 0 1 1 1 1 Dynein heavy chain, N-terminal region 1 Mei5_like PF17021.5 CBK21315.2 - 0.1 12.7 0.0 0.14 12.2 0.0 1.2 1 0 0 1 1 1 0 Putative double-strand recombination repair-like Vps52 PF04129.12 CBK21316.2 - 1.8e-26 93.0 1.1 2.2e-26 92.7 1.1 1.0 1 0 0 1 1 1 1 Vps52 / Sac2 family Band_7 PF01145.25 CBK21317.2 - 8.3e-22 78.0 2.4 8.3e-22 78.0 2.4 2.3 1 1 1 2 2 2 1 SPFH domain / Band 7 family DivIVA PF05103.13 CBK21317.2 - 0.0049 17.0 5.8 0.011 15.9 5.8 1.5 1 0 0 1 1 1 1 DivIVA protein Yqai PF09466.10 CBK21317.2 - 0.032 14.5 0.1 0.084 13.2 0.1 1.7 1 0 0 1 1 1 0 Hypothetical protein Yqai V-ATPase_G_2 PF16999.5 CBK21317.2 - 0.039 14.4 8.3 0.047 14.1 7.5 1.5 1 1 0 1 1 1 0 Vacuolar (H+)-ATPase G subunit Caudo_TAP PF02413.17 CBK21317.2 - 0.29 11.3 5.1 1.7 8.8 5.1 2.0 1 1 0 1 1 1 0 Caudovirales tail fibre assembly protein, lambda gpK Flot PF15975.5 CBK21317.2 - 0.46 10.7 6.0 4.6 7.4 6.1 2.2 1 1 1 2 2 2 0 Flotillin V-ATPase_G PF03179.15 CBK21317.2 - 0.97 10.0 11.3 0.11 13.0 3.7 2.2 1 1 1 2 2 2 0 Vacuolar (H+)-ATPase G subunit He_PIG PF05345.12 CBK21318.2 - 1.6e-05 25.0 0.9 4.5e-05 23.5 0.1 2.1 2 0 0 2 2 2 1 Putative Ig domain Orf78 PF06024.12 CBK21318.2 - 0.039 14.2 0.1 0.061 13.6 0.1 1.3 1 0 0 1 1 1 0 Orf78 (ac78) Shisa PF13908.6 CBK21318.2 - 0.079 13.2 0.4 0.12 12.6 0.4 1.2 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator DUF898 PF05987.13 CBK21318.2 - 0.13 11.3 0.1 0.16 11.0 0.1 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF898) DUF1180 PF06679.12 CBK21318.2 - 0.14 12.6 0.3 0.2 12.1 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) DUF4834 PF16118.5 CBK21318.2 - 0.14 13.1 0.5 0.24 12.4 0.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) TMEM154 PF15102.6 CBK21318.2 - 0.15 12.0 0.1 0.23 11.4 0.1 1.3 1 0 0 1 1 1 0 TMEM154 protein family OAD_gamma PF04277.13 CBK21318.2 - 0.2 12.3 1.9 0.3 11.7 1.9 1.3 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain EphA2_TM PF14575.6 CBK21318.2 - 0.46 11.4 2.7 0.83 10.6 2.7 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF4389 PF14333.6 CBK21318.2 - 0.48 10.4 3.7 1 9.3 3.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4389) Pyr_redox_2 PF07992.14 CBK21319.2 - 7.2e-58 196.1 0.0 1e-57 195.6 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 CBK21319.2 - 3.1e-17 62.9 3.2 1.1e-16 61.1 0.1 2.9 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 CBK21319.2 - 4.7e-12 46.1 0.2 1.6e-11 44.4 0.1 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox_3 PF13738.6 CBK21319.2 - 3.9e-11 42.8 0.0 2.5e-10 40.1 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 CBK21319.2 - 7.9e-08 32.4 0.8 0.025 14.8 0.1 3.1 3 0 0 3 3 3 2 NAD(P)-binding Rossmann-like domain Rhodanese PF00581.20 CBK21319.2 - 6.6e-06 26.6 0.0 2.9e-05 24.5 0.0 2.0 2 0 0 2 2 2 1 Rhodanese-like domain HI0933_like PF03486.14 CBK21319.2 - 1.5e-05 23.9 2.4 0.2 10.3 0.0 3.9 3 1 1 4 4 4 2 HI0933-like protein K_oxygenase PF13434.6 CBK21319.2 - 0.00027 20.2 0.0 0.00049 19.4 0.0 1.3 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) Lycopene_cycl PF05834.12 CBK21319.2 - 0.00041 19.5 0.9 0.11 11.5 0.2 3.0 2 1 1 3 3 3 1 Lycopene cyclase protein 3HCDH_N PF02737.18 CBK21319.2 - 0.0012 18.7 0.0 0.0024 17.8 0.0 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DAO PF01266.24 CBK21319.2 - 0.0019 17.9 0.9 0.69 9.4 0.2 3.7 4 0 0 4 4 4 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 CBK21319.2 - 0.0047 16.9 1.3 2.9 7.8 0.2 3.9 3 1 1 4 4 4 1 FAD-NAD(P)-binding NAD_binding_7 PF13241.6 CBK21319.2 - 0.0055 17.1 0.0 0.13 12.8 0.0 2.5 2 0 0 2 2 2 1 Putative NAD(P)-binding FAD_binding_2 PF00890.24 CBK21319.2 - 0.011 14.9 1.0 2.6 7.0 0.1 3.2 3 0 0 3 3 3 0 FAD binding domain TrkA_N PF02254.18 CBK21319.2 - 0.014 15.7 0.2 0.18 12.1 0.1 2.4 2 0 0 2 2 2 0 TrkA-N domain Cyclin_N PF00134.23 CBK21320.2 - 2.6e-07 30.4 1.4 5.2e-06 26.2 0.1 2.2 2 0 0 2 2 2 2 Cyclin, N-terminal domain MutS_V PF00488.21 CBK21321.2 - 1e-71 240.8 0.0 1.8e-71 240.1 0.0 1.3 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 CBK21321.2 - 1.6e-31 110.0 0.1 2.5e-31 109.4 0.1 1.3 1 0 0 1 1 1 1 MutS domain III MutS_IV PF05190.18 CBK21321.2 - 2.9e-08 33.9 0.1 9.5e-08 32.3 0.0 1.9 2 0 0 2 2 2 1 MutS family domain IV AAA_14 PF13173.6 CBK21321.2 - 0.12 12.4 0.0 0.4 10.7 0.0 1.9 2 1 0 2 2 2 0 AAA domain RRM_1 PF00076.22 CBK21322.2 - 7.9e-31 105.7 0.0 1.2e-15 57.1 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.8 CBK21322.2 - 0.003 17.6 0.0 0.024 14.7 0.0 2.2 2 0 0 2 2 2 1 Limkain b1 Ribosomal_L29e PF01779.17 CBK21323.2 - 2.4e-20 72.5 9.2 2.4e-20 72.5 9.2 1.6 2 0 0 2 2 2 1 Ribosomal L29e protein family Radical_SAM PF04055.21 CBK21324.2 - 7.7e-09 36.1 1.4 2.3e-08 34.6 1.4 1.8 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_12 PF13353.6 CBK21324.2 - 1.8e-06 28.3 0.3 1.8e-06 28.3 0.3 1.9 2 0 0 2 2 2 1 4Fe-4S single cluster domain Fer4_14 PF13394.6 CBK21324.2 - 7.5e-05 22.8 2.3 8e-05 22.8 0.4 2.0 2 0 0 2 2 2 1 4Fe-4S single cluster domain GTP_EFTU PF00009.27 CBK21325.2 - 3.5e-27 95.2 6.6 3.1e-26 92.1 3.5 2.6 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain IF-2 PF11987.8 CBK21325.2 - 1.4e-13 50.9 0.6 7.4e-13 48.5 0.2 2.3 2 0 0 2 2 2 1 Translation-initiation factor 2 MMR_HSR1 PF01926.23 CBK21325.2 - 1.6e-10 41.0 0.3 4.7e-10 39.6 0.3 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 CBK21325.2 - 6.4e-05 22.5 0.0 0.00013 21.5 0.0 1.5 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit PduV-EutP PF10662.9 CBK21325.2 - 0.00072 19.3 0.2 0.0027 17.5 0.2 2.0 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation Arf PF00025.21 CBK21325.2 - 0.003 17.0 0.0 0.0072 15.8 0.0 1.5 1 0 0 1 1 1 1 ADP-ribosylation factor family FeoB_N PF02421.18 CBK21325.2 - 0.0043 16.6 0.1 0.0092 15.5 0.1 1.6 1 1 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 CBK21325.2 - 0.0049 16.9 0.5 0.16 12.0 0.0 2.8 2 1 1 3 3 3 1 Dynamin family Roc PF08477.13 CBK21325.2 - 0.011 16.0 0.0 0.029 14.6 0.0 1.8 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase Flg_hook PF02120.16 CBK21325.2 - 0.032 14.1 0.1 0.098 12.6 0.1 1.8 1 0 0 1 1 1 0 Flagellar hook-length control protein FliK Ras PF00071.22 CBK21325.2 - 0.046 13.3 0.1 0.12 12.0 0.1 1.7 1 0 0 1 1 1 0 Ras family GTP_EFTU_D4 PF14578.6 CBK21326.2 - 0.017 15.0 0.1 0.019 14.9 0.1 1.1 1 0 0 1 1 1 0 Elongation factor Tu domain 4 Lipl32 PF12103.8 CBK21326.2 - 0.053 13.2 0.0 0.06 13.0 0.0 1.0 1 0 0 1 1 1 0 Surface lipoprotein of Spirochaetales order FYVE PF01363.21 CBK21327.2 - 0.008 16.3 15.9 0.016 15.3 15.9 1.4 1 0 0 1 1 1 1 FYVE zinc finger AAA_13 PF13166.6 CBK21327.2 - 0.036 12.7 8.5 0.18 10.4 6.8 2.0 2 0 0 2 2 2 0 AAA domain GIT_CC PF16559.5 CBK21327.2 - 0.14 12.0 2.4 0.35 10.8 1.9 1.9 1 1 1 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor ATG16 PF08614.11 CBK21327.2 - 0.24 11.6 15.5 0.092 13.0 10.8 2.3 2 1 0 2 2 2 0 Autophagy protein 16 (ATG16) ADIP PF11559.8 CBK21327.2 - 0.27 11.3 15.5 0.13 12.3 12.8 1.8 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding DUF16 PF01519.16 CBK21327.2 - 3.2 8.3 9.5 3.5 8.2 7.7 2.1 2 1 0 2 2 2 0 Protein of unknown function DUF16 KLRAQ PF10205.9 CBK21327.2 - 3.5 7.9 11.9 3.1 8.1 7.0 2.6 1 1 1 2 2 2 0 Predicted coiled-coil domain-containing protein Asp PF00026.23 CBK21328.2 - 6.6e-08 32.3 0.0 7.3e-08 32.2 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease Thioredoxin PF00085.20 CBK21329.2 - 8.2e-22 77.1 0.0 1.1e-21 76.8 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_9 PF14595.6 CBK21329.2 - 4.8e-06 26.4 0.0 6.1e-06 26.0 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin OST3_OST6 PF04756.13 CBK21329.2 - 5e-05 22.8 1.3 0.00013 21.5 0.0 1.9 2 0 0 2 2 2 1 OST3 / OST6 family, transporter family Thioredoxin_8 PF13905.6 CBK21329.2 - 0.003 17.9 0.2 0.94 9.8 0.0 2.5 2 1 1 3 3 3 2 Thioredoxin-like TraF PF13728.6 CBK21329.2 - 0.0099 15.7 0.0 0.013 15.4 0.0 1.1 1 0 0 1 1 1 1 F plasmid transfer operon protein Thioredoxin_3 PF13192.6 CBK21329.2 - 0.022 14.8 0.0 0.039 14.0 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin domain DUF953 PF06110.11 CBK21329.2 - 0.025 14.2 0.4 0.11 12.1 0.4 1.9 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF953) Thioredoxin_2 PF13098.6 CBK21329.2 - 0.08 13.4 0.0 0.22 12.0 0.0 1.7 1 1 0 1 1 1 0 Thioredoxin-like domain Calici_PP_N PF08405.11 CBK21329.2 - 0.11 11.3 0.6 0.15 10.8 0.6 1.2 1 0 0 1 1 1 0 Viral polyprotein N-terminal HSP20 PF00011.21 CBK21331.2 - 3.2e-27 94.7 2.7 3.8e-27 94.4 2.7 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 CBK21331.2 - 3e-13 49.1 0.0 5e-13 48.4 0.0 1.4 1 0 0 1 1 1 1 HSP20-like domain found in ArsA DUF563 PF04577.14 CBK21332.2 - 1.9e-17 64.1 1.1 5.3e-17 62.7 0.4 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF563) HSP20 PF00011.21 CBK21333.2 - 3.2e-27 94.7 2.7 3.8e-27 94.4 2.7 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 CBK21333.2 - 3e-13 49.1 0.0 5e-13 48.4 0.0 1.4 1 0 0 1 1 1 1 HSP20-like domain found in ArsA Snf7 PF03357.21 CBK21334.2 - 0.0095 15.5 6.5 0.014 15.0 6.5 1.2 1 0 0 1 1 1 1 Snf7 eIF3_subunit PF08597.10 CBK21334.2 - 0.011 15.7 4.5 0.011 15.7 4.5 1.1 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit BNIP2 PF12496.8 CBK21334.2 - 0.22 12.0 3.3 0.26 11.7 3.3 1.1 1 0 0 1 1 1 0 Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2 Nuc_sug_transp PF04142.15 CBK21335.2 - 5.3e-78 262.4 29.1 9.2e-78 261.6 29.1 1.3 1 1 0 1 1 1 1 Nucleotide-sugar transporter EamA PF00892.20 CBK21335.2 - 6.2e-09 36.2 33.0 4.2e-08 33.4 10.8 2.5 2 1 0 2 2 2 2 EamA-like transporter family UAA PF08449.11 CBK21335.2 - 4.8e-07 29.3 21.7 0.0011 18.2 21.2 3.5 1 1 0 1 1 1 1 UAA transporter family TPT PF03151.16 CBK21335.2 - 1.7e-05 24.4 23.5 0.0013 18.2 22.7 2.7 1 1 1 2 2 2 1 Triose-phosphate Transporter family CRT-like PF08627.10 CBK21335.2 - 2.4e-05 23.5 14.8 2.4e-05 23.5 14.8 2.4 1 1 1 2 2 2 2 CRT-like, chloroquine-resistance transporter-like DUF760 PF05542.11 CBK21335.2 - 0.047 14.1 0.5 0.19 12.1 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF760) CBFB_NFYA PF02045.15 CBK21336.2 - 4.3e-23 81.7 5.2 5.3e-23 81.4 5.2 1.1 1 0 0 1 1 1 1 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B DnaJ PF00226.31 CBK21337.2 - 1.7e-16 60.1 1.3 5.4e-16 58.5 1.3 1.9 1 0 0 1 1 1 1 DnaJ domain DUF3177 PF11375.8 CBK21337.2 - 0.044 13.5 0.1 0.081 12.7 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3177) Menin PF05053.13 CBK21337.2 - 0.16 10.3 6.2 0.27 9.6 6.2 1.3 1 0 0 1 1 1 0 Menin Secretin_N_2 PF07655.13 CBK21337.2 - 1.3 9.7 16.1 2.8 8.5 16.1 1.6 1 0 0 1 1 1 0 Secretin N-terminal domain Exonuc_VII_L PF02601.15 CBK21338.2 - 0.41 10.2 9.3 0.51 9.8 9.3 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit HI0933_like PF03486.14 CBK21338.2 - 0.95 8.1 3.1 1.3 7.7 3.1 1.3 1 0 0 1 1 1 0 HI0933-like protein DUF445 PF04286.12 CBK21338.2 - 2 8.1 11.5 1.8 8.3 11.5 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF445) ExbD PF02472.16 CBK21339.2 - 0.096 12.9 0.6 0.16 12.1 0.6 1.4 1 0 0 1 1 1 0 Biopolymer transport protein ExbD/TolR DUF3896 PF13035.6 CBK21339.2 - 0.24 11.6 10.0 0.61 10.3 10.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3896) ESM4 PF15952.5 CBK21339.2 - 0.25 11.8 2.3 0.31 11.5 2.3 1.2 1 0 0 1 1 1 0 Enhancer of split M4 family RabGAP-TBC PF00566.18 CBK21340.2 - 3.1e-14 53.2 3.4 5.5e-14 52.3 3.4 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Spec3 PF15795.5 CBK21341.2 - 4.1e-07 30.4 6.5 1.4e-06 28.8 6.5 1.9 1 1 0 1 1 1 1 Ectodermal ciliogenesis protein MFS_1 PF07690.16 CBK21342.2 - 1.5e-06 27.4 10.2 8.5e-06 24.9 8.3 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF3792 PF12670.7 CBK21342.2 - 0.013 15.6 4.3 0.013 15.6 4.3 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3792) Sugar_tr PF00083.24 CBK21342.2 - 0.15 10.9 5.3 0.028 13.3 0.9 1.7 1 1 1 2 2 2 0 Sugar (and other) transporter UDPG_MGDP_dh_N PF03721.14 CBK21345.2 - 3.5e-38 131.1 0.1 8.8e-38 129.7 0.1 1.6 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh PF00984.19 CBK21345.2 - 1.2e-23 83.2 0.0 2.5e-23 82.1 0.0 1.6 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain UDPG_MGDP_dh_C PF03720.15 CBK21345.2 - 8.7e-23 80.7 0.5 1.2e-21 77.1 0.4 2.3 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain NAD_binding_2 PF03446.15 CBK21345.2 - 1.6e-05 25.2 0.2 0.00012 22.2 0.0 2.6 2 1 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase 2-Hacid_dh_C PF02826.19 CBK21345.2 - 0.00028 20.3 0.2 0.11 11.8 0.0 2.4 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.18 CBK21345.2 - 0.012 15.5 1.3 0.037 13.9 0.0 2.5 3 1 0 3 3 3 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.23 CBK21345.2 - 0.058 13.4 0.1 0.73 9.8 0.0 2.3 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Runt PF00853.19 CBK21345.2 - 0.14 11.7 0.4 1.9 8.0 0.1 2.3 1 1 1 2 2 2 0 Runt domain Pyr_redox PF00070.27 CBK21345.2 - 0.3 11.7 2.2 1.3 9.6 0.8 2.7 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Cation_efflux PF01545.21 CBK21346.2 - 2.6e-39 135.0 1.7 3.9e-39 134.5 1.7 1.3 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 CBK21346.2 - 0.00028 20.9 0.1 0.00053 20.1 0.1 1.4 1 0 0 1 1 1 1 Dimerisation domain of Zinc Transporter Galactosyl_T PF01762.21 CBK21347.2 - 3.9e-33 114.9 0.0 5.7e-33 114.4 0.0 1.3 1 0 0 1 1 1 1 Galactosyltransferase Galactosyl_T PF01762.21 CBK21348.2 - 2.2e-31 109.2 0.0 3.4e-31 108.6 0.0 1.3 1 0 0 1 1 1 1 Galactosyltransferase Galactosyl_T PF01762.21 CBK21349.2 - 2.4e-33 115.6 0.0 2.9e-33 115.4 0.0 1.1 1 0 0 1 1 1 1 Galactosyltransferase Trypan_PARP PF05887.11 CBK21351.2 - 0.00029 20.8 10.4 0.00041 20.3 10.4 1.2 1 0 0 1 1 1 1 Procyclic acidic repetitive protein (PARP) LRR_8 PF13855.6 CBK21351.2 - 0.03 14.1 1.4 0.9 9.4 0.0 3.0 2 1 1 3 3 3 0 Leucine rich repeat DUF5525 PF17663.1 CBK21351.2 - 1.9 6.5 15.7 2.6 6.0 15.7 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5525) ArfGap PF01412.18 CBK21352.2 - 1.6e-34 118.4 0.1 2.3e-34 117.9 0.1 1.3 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf zf-dskA_traR PF01258.17 CBK21352.2 - 0.024 14.6 1.1 0.59 10.1 0.1 2.6 2 0 0 2 2 2 0 Prokaryotic dksA/traR C4-type zinc finger zf-C2H2 PF00096.26 CBK21353.2 - 2.1e-19 68.8 31.8 5e-05 23.5 0.1 4.4 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 CBK21353.2 - 2.5e-17 62.4 32.6 3.5e-09 36.7 0.7 5.1 5 0 0 5 5 5 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 CBK21353.2 - 9.8e-13 47.8 30.6 0.003 18.2 3.8 4.4 4 0 0 4 4 4 4 C2H2-type zinc finger zf-met PF12874.7 CBK21353.2 - 1.9e-07 31.2 4.4 0.38 11.2 0.0 4.8 4 1 1 5 5 5 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 CBK21353.2 - 0.00036 20.7 9.8 0.17 12.2 0.1 4.5 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding zf-C2H2_8 PF15909.5 CBK21353.2 - 0.00038 20.7 11.5 0.027 14.8 6.6 3.2 1 1 2 3 3 3 2 C2H2-type zinc ribbon THOC7 PF05615.13 CBK21353.2 - 0.0018 18.5 1.4 0.0075 16.6 1.4 1.8 1 1 0 1 1 1 1 Tho complex subunit 7 zf-C2H2_11 PF16622.5 CBK21353.2 - 0.002 17.9 20.1 0.13 12.0 1.0 3.9 4 0 0 4 4 4 3 zinc-finger C2H2-type zf-C2H2_aberr PF17017.5 CBK21353.2 - 0.011 16.0 14.5 0.89 9.7 1.5 3.4 2 1 1 3 3 3 0 Aberrant zinc-finger FOXP-CC PF16159.5 CBK21353.2 - 1.1 9.9 19.8 12 6.6 0.4 5.0 1 1 4 5 5 5 0 FOXP coiled-coil domain Toxin_8 PF07365.12 CBK21353.2 - 2.6 8.3 7.7 0.16 12.2 1.3 2.2 2 0 0 2 2 2 0 Alpha conotoxin precursor AhpC-TSA PF00578.21 CBK21354.2 - 1.2e-35 122.1 0.0 1.6e-35 121.7 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family 1-cysPrx_C PF10417.9 CBK21354.2 - 2.3e-12 46.6 0.0 4.8e-12 45.5 0.0 1.5 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin Redoxin PF08534.10 CBK21354.2 - 1.2e-11 44.5 0.0 1.6e-11 44.1 0.0 1.1 1 0 0 1 1 1 1 Redoxin LMWPc PF01451.21 CBK21356.2 - 7.8e-25 87.9 0.0 8.6e-25 87.8 0.0 1.0 1 0 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase Glyco_transf_49 PF13896.6 CBK21357.2 - 3.6e-20 72.6 2.8 9.4e-17 61.3 0.8 3.2 1 1 0 2 2 2 2 Glycosyl-transferase for dystroglycan PI3K_1B_p101 PF10486.9 CBK21357.2 - 6.6 4.4 7.5 9.5 3.9 7.5 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Sec63 PF02889.16 CBK21358.2 - 3.1e-131 436.2 0.1 7.9e-80 267.7 0.1 2.3 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.29 CBK21358.2 - 2.8e-42 144.5 0.5 7e-24 84.5 0.1 3.4 3 0 0 3 3 3 2 DEAD/DEAH box helicase Helicase_PWI PF18149.1 CBK21358.2 - 5.9e-31 106.9 1.9 1.5e-30 105.6 0.3 2.4 2 0 0 2 2 2 1 N-terminal helicase PWI domain ResIII PF04851.15 CBK21358.2 - 2.5e-19 69.9 0.0 1.8e-11 44.4 0.0 2.8 3 0 0 3 3 3 2 Type III restriction enzyme, res subunit Helicase_C PF00271.31 CBK21358.2 - 7.2e-10 39.2 0.0 4.8e-07 30.1 0.0 3.9 3 2 0 3 3 3 1 Helicase conserved C-terminal domain AAA_19 PF13245.6 CBK21358.2 - 0.0029 17.9 0.5 0.25 11.7 0.0 3.3 3 0 0 3 3 3 1 AAA domain AAA_22 PF13401.6 CBK21358.2 - 0.012 15.9 0.1 0.18 12.1 0.0 3.0 2 1 0 2 2 2 0 AAA domain NAD_binding_2 PF03446.15 CBK21362.2 - 7.9e-25 87.9 0.2 1.1e-24 87.4 0.2 1.1 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 CBK21362.2 - 4.6e-10 39.8 0.4 7.9e-10 39.0 0.4 1.3 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase CBF PF03914.17 CBK21363.2 - 1.9e-43 148.4 32.9 1.9e-40 138.7 30.1 4.2 2 1 0 2 2 2 1 CBF/Mak21 family BUD22 PF09073.10 CBK21363.2 - 0.0013 18.1 64.2 0.0013 18.1 64.2 3.2 3 0 0 3 3 3 1 BUD22 eIF-3c_N PF05470.12 CBK21363.2 - 0.0083 14.5 0.4 0.0083 14.5 0.4 2.3 1 1 1 2 2 2 1 Eukaryotic translation initiation factor 3 subunit 8 N-terminus GREB1 PF15782.5 CBK21363.2 - 0.029 11.5 15.8 0.053 10.7 15.8 1.3 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer NOC3p PF07540.11 CBK21363.2 - 0.043 14.3 0.1 0.043 14.3 0.1 4.0 3 0 0 3 3 3 0 Nucleolar complex-associated protein Membralin PF09746.9 CBK21363.2 - 3.6 6.5 17.1 0.058 12.4 8.0 2.4 2 0 0 2 2 2 0 Tumour-associated protein DUF3630 PF12305.8 CBK21364.2 - 0.096 12.8 0.1 0.19 11.8 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3630) DUF563 PF04577.14 CBK21365.2 - 5e-18 66.0 0.7 1.6e-17 64.4 0.3 2.0 1 1 1 2 2 2 1 Protein of unknown function (DUF563) PCIF1_WW PF12237.8 CBK21365.2 - 0.079 12.6 0.0 0.58 9.8 0.0 2.3 2 0 0 2 2 2 0 Phosphorylated CTD interacting factor 1 WW domain NAD_binding_2 PF03446.15 CBK21366.2 - 7.1e-44 149.8 0.2 1.1e-43 149.2 0.2 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 CBK21366.2 - 1.2e-34 119.2 0.1 2.1e-34 118.4 0.1 1.4 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase Shikimate_DH PF01488.20 CBK21366.2 - 0.0012 18.9 0.0 0.003 17.6 0.0 1.6 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase 2-Hacid_dh_C PF02826.19 CBK21366.2 - 0.11 11.8 0.0 0.17 11.2 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ADH_N PF08240.12 CBK21368.2 - 3.5e-22 78.4 3.2 5.8e-22 77.6 3.2 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 CBK21368.2 - 2.8e-06 27.3 0.0 1.3e-05 25.2 0.0 1.9 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 CBK21368.2 - 0.0012 19.9 0.0 0.0019 19.3 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 CBK21368.2 - 0.026 14.0 0.0 0.038 13.5 0.0 1.2 1 0 0 1 1 1 0 Glucose dehydrogenase C-terminus 2-Hacid_dh_C PF02826.19 CBK21368.2 - 0.13 11.6 0.0 0.23 10.8 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DCX PF03607.17 CBK21368.2 - 0.15 12.2 0.0 0.41 10.8 0.0 1.7 1 0 0 1 1 1 0 Doublecortin CENP-F_leu_zip PF10473.9 CBK21369.2 - 0.00015 21.8 13.8 0.00024 21.2 13.8 1.2 1 0 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF4407 PF14362.6 CBK21369.2 - 0.008 15.6 1.5 0.008 15.6 1.5 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4407) UPF0242 PF06785.11 CBK21369.2 - 0.021 14.9 10.6 0.038 14.1 10.6 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Leu_zip PF15294.6 CBK21369.2 - 0.043 13.3 11.9 0.065 12.7 11.9 1.2 1 0 0 1 1 1 0 Leucine zipper Apolipoprotein PF01442.18 CBK21369.2 - 0.048 13.5 10.2 1.3 8.8 0.1 2.1 2 0 0 2 2 2 0 Apolipoprotein A1/A4/E domain DUF4400 PF14348.6 CBK21369.2 - 0.057 12.9 2.2 0.072 12.6 1.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4400) Spc7 PF08317.11 CBK21369.2 - 0.12 11.2 16.0 0.17 10.8 16.0 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein APG6_N PF17675.1 CBK21369.2 - 0.18 12.4 16.1 0.29 11.7 16.1 1.3 1 0 0 1 1 1 0 Apg6 coiled-coil region DUF5324 PF17258.2 CBK21369.2 - 0.71 9.5 11.9 0.73 9.5 7.9 2.4 1 1 2 3 3 3 0 Family of unknown function (DUF5324) ZapB PF06005.12 CBK21369.2 - 0.91 10.0 19.4 0.49 10.9 6.7 2.4 1 1 1 2 2 2 0 Cell division protein ZapB DUF883 PF05957.13 CBK21369.2 - 1.2 9.8 7.8 1.4 9.6 1.0 2.7 3 0 0 3 3 2 0 Bacterial protein of unknown function (DUF883) FapA PF03961.13 CBK21369.2 - 1.5 7.4 10.7 2.1 6.9 10.7 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A V_ATPase_I PF01496.19 CBK21369.2 - 2.1 6.2 8.9 3.7 5.3 8.9 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF2968 PF11180.8 CBK21369.2 - 3 7.4 11.5 2.3 7.8 3.8 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF2968) DUF4140 PF13600.6 CBK21369.2 - 6 7.4 11.4 4.4e+02 1.4 11.4 2.4 1 1 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) MgsA_C PF12002.8 CBK21370.2 - 1.5e-39 135.7 0.0 2.1e-39 135.1 0.0 1.2 1 0 0 1 1 1 1 MgsA AAA+ ATPase C terminal AAA_assoc_2 PF16193.5 CBK21370.2 - 1.8e-19 69.9 0.1 4.6e-19 68.5 0.1 1.8 1 0 0 1 1 1 1 AAA C-terminal domain AAA PF00004.29 CBK21370.2 - 7.6e-14 52.3 0.0 1.6e-13 51.2 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 CBK21370.2 - 1.8e-09 37.5 0.0 3.5e-09 36.6 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 CBK21370.2 - 3.4e-06 27.1 0.0 2.3e-05 24.4 0.0 2.3 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.26 CBK21370.2 - 4.9e-06 26.4 0.0 0.0059 16.3 0.0 2.2 2 0 0 2 2 2 2 Sigma-54 interaction domain Sigma54_activ_2 PF14532.6 CBK21370.2 - 1.5e-05 25.1 0.0 7.8e-05 22.8 0.0 2.0 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_16 PF13191.6 CBK21370.2 - 2.9e-05 24.5 1.5 0.15 12.4 0.0 3.5 3 1 0 4 4 4 2 AAA ATPase domain AAA_14 PF13173.6 CBK21370.2 - 7e-05 22.9 0.0 0.00016 21.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain Rad17 PF03215.15 CBK21370.2 - 0.00011 22.2 0.0 0.00022 21.2 0.0 1.5 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_18 PF13238.6 CBK21370.2 - 0.0016 19.0 0.2 0.013 16.0 0.0 2.3 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 CBK21370.2 - 0.0056 17.1 0.0 0.01 16.2 0.0 1.4 1 0 0 1 1 1 1 RNA helicase Mg_chelatase PF01078.21 CBK21370.2 - 0.0072 15.7 0.0 3.5 6.9 0.0 2.3 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_22 PF13401.6 CBK21370.2 - 0.02 15.2 3.1 0.2 11.9 0.5 2.9 2 1 1 3 3 3 0 AAA domain ABC_tran PF00005.27 CBK21370.2 - 0.023 15.2 0.9 0.068 13.7 0.1 2.1 2 1 0 2 2 2 0 ABC transporter AAA_33 PF13671.6 CBK21370.2 - 0.056 13.6 0.0 0.12 12.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 CBK21370.2 - 0.39 11.2 0.0 0.39 11.2 0.0 2.5 2 1 0 2 2 1 0 AAA domain ADH_N PF08240.12 CBK21371.2 - 4.2e-08 33.0 0.0 4e-07 29.9 0.0 2.1 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 CBK21371.2 - 4.9e-06 26.6 0.0 8.7e-06 25.7 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase DUF2119 PF09892.9 CBK21371.2 - 0.19 11.1 0.0 0.3 10.5 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2119) Pkinase PF00069.25 CBK21372.2 - 1.9e-65 220.9 0.0 2.4e-65 220.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBK21372.2 - 3.1e-30 105.3 0.0 4.2e-30 104.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CBK21372.2 - 0.008 15.5 0.0 0.011 15.1 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 CBK21372.2 - 0.0085 15.5 0.0 0.013 14.9 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CBK21372.2 - 0.039 13.9 0.0 0.067 13.1 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 CBK21372.2 - 0.058 12.3 0.1 0.14 11.1 0.1 1.6 1 1 0 1 1 1 0 Haspin like kinase domain Pkinase_fungal PF17667.1 CBK21372.2 - 0.079 11.7 0.0 0.12 11.1 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase FTA2 PF13095.6 CBK21372.2 - 0.14 11.8 0.1 0.48 10.0 0.0 1.8 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 PsiA PF06952.11 CBK21373.2 - 0.029 13.6 0.0 0.029 13.6 0.0 1.0 1 0 0 1 1 1 0 PsiA protein Med14 PF08638.11 CBK21375.2 - 2.6e-24 85.7 0.0 5.7e-24 84.6 0.0 1.6 1 0 0 1 1 1 1 Mediator complex subunit MED14 CBFD_NFYB_HMF PF00808.23 CBK21376.2 - 1.6e-05 25.1 0.2 5.6e-05 23.4 0.1 1.9 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CCT PF06203.14 CBK21377.2 - 3.6e-05 23.7 2.9 6.3e-05 22.9 2.9 1.5 1 0 0 1 1 1 1 CCT motif Oxysterol_BP PF01237.18 CBK21378.2 - 3.9e-30 104.9 0.3 3.1e-28 98.7 0.0 2.0 1 1 1 2 2 2 2 Oxysterol-binding protein FERM_M PF00373.18 CBK21379.2 - 8.2e-12 45.6 0.0 1.7e-11 44.6 0.0 1.5 1 0 0 1 1 1 1 FERM central domain MyTH4 PF00784.17 CBK21379.2 - 1.5e-10 41.5 0.0 3.9e-10 40.2 0.0 1.7 1 0 0 1 1 1 1 MyTH4 domain RA PF00788.23 CBK21379.2 - 0.023 15.3 0.0 8.9 7.0 0.0 3.6 2 1 1 3 3 3 0 Ras association (RalGDS/AF-6) domain Peptidase_S24 PF00717.23 CBK21380.2 - 3.8e-07 30.0 0.0 7.8e-07 29.0 0.0 1.4 1 0 0 1 1 1 1 Peptidase S24-like Peptidase_S26 PF10502.9 CBK21380.2 - 0.00032 20.5 0.0 0.37 10.6 0.0 2.4 1 1 1 2 2 2 2 Signal peptidase, peptidase S26 AHSA1 PF08327.11 CBK21381.2 - 9.7e-11 42.0 0.0 1.2e-10 41.7 0.0 1.1 1 0 0 1 1 1 1 Activator of Hsp90 ATPase homolog 1-like protein RNA_pol_Rpb1_5 PF04998.17 CBK21382.2 - 1.7e-91 306.3 0.0 4.3e-91 305.1 0.0 1.7 1 1 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 CBK21382.2 - 1.1e-59 201.4 0.0 2.2e-59 200.4 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.18 CBK21382.2 - 3.2e-34 118.1 0.0 7.6e-34 116.9 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.17 CBK21382.2 - 2.9e-18 65.8 0.0 2.9e-18 65.8 0.0 2.5 3 0 0 3 3 3 1 RNA polymerase Rpb1, domain 4 SnoaL_4 PF13577.6 CBK21382.2 - 0.094 12.8 0.0 0.32 11.1 0.0 2.0 1 0 0 1 1 1 0 SnoaL-like domain RNA_pol_Rpb1_1 PF04997.12 CBK21383.2 - 2.6e-24 86.1 0.2 3e-24 85.9 0.2 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNase_PH PF01138.21 CBK21384.2 - 7.1e-23 81.6 0.1 9.8e-23 81.1 0.1 1.2 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 CBK21384.2 - 0.00093 19.2 0.0 0.0017 18.3 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 MORN_2 PF07661.13 CBK21385.2 - 4.2e-09 35.6 8.1 0.28 11.6 0.1 8.0 8 0 0 8 8 8 3 MORN repeat variant MORN PF02493.20 CBK21385.2 - 0.28 11.2 10.4 1.3 9.1 0.8 5.1 5 0 0 5 5 5 0 MORN repeat HSP70 PF00012.20 CBK21386.2 - 1.9e-08 33.0 0.0 2.5e-08 32.6 0.0 1.3 1 1 0 1 1 1 1 Hsp70 protein Snf7 PF03357.21 CBK21387.2 - 1.6e-05 24.6 8.0 1.9e-05 24.3 8.0 1.1 1 0 0 1 1 1 1 Snf7 BING4CT PF08149.11 CBK21388.2 - 5.6e-31 106.2 0.0 5.2e-30 103.1 0.0 2.3 2 0 0 2 2 2 1 BING4CT (NUC141) domain WD40 PF00400.32 CBK21388.2 - 0.00099 19.9 0.6 20 6.2 0.0 4.5 5 0 0 5 5 5 2 WD domain, G-beta repeat SH2_2 PF14633.6 CBK21389.2 - 0.011 15.2 0.2 0.011 15.2 0.2 1.0 1 0 0 1 1 1 0 SH2 domain SH3_1 PF00018.28 CBK21391.2 - 2e-28 97.7 2.8 1.5e-10 40.5 0.1 3.5 3 0 0 3 3 3 3 SH3 domain SH3_2 PF07653.17 CBK21391.2 - 1.5e-25 88.6 1.3 5.6e-11 41.9 0.0 3.3 3 0 0 3 3 3 3 Variant SH3 domain SH3_9 PF14604.6 CBK21391.2 - 2.5e-24 84.9 2.9 9.9e-10 38.1 0.0 3.4 3 0 0 3 3 3 3 Variant SH3 domain SH3_4 PF06347.13 CBK21391.2 - 2.3e-05 24.1 0.8 0.11 12.3 0.0 3.7 3 0 0 3 3 3 1 Bacterial SH3 domain SH3_3 PF08239.11 CBK21391.2 - 6.2e-05 23.2 4.3 0.77 10.1 0.3 3.6 3 0 0 3 3 3 2 Bacterial SH3 domain Trypan_PARP PF05887.11 CBK21391.2 - 0.00039 20.4 39.1 0.00039 20.4 39.1 3.3 2 1 1 3 3 2 2 Procyclic acidic repetitive protein (PARP) DUF237 PF03072.14 CBK21391.2 - 0.0013 18.7 1.1 9.1 6.3 0.0 3.3 3 0 0 3 3 3 1 Domain of unknown function (DUF237) hSH3 PF14603.6 CBK21391.2 - 0.003 18.0 0.0 0.12 12.8 0.0 3.4 2 1 1 3 3 3 1 Helically-extended SH3 domain Methyltransf_5 PF01795.19 CBK21391.2 - 0.0095 15.5 7.5 0.1 12.1 0.4 2.7 1 1 2 3 3 3 2 MraW methylase family PBP5_C PF07943.13 CBK21391.2 - 0.052 13.8 7.9 3 8.1 0.1 4.0 3 1 1 4 4 4 0 Penicillin-binding protein 5, C-terminal domain Cag12 PF13117.6 CBK21391.2 - 0.11 13.0 12.7 2.9 8.5 0.6 3.4 3 0 0 3 3 3 0 Cag pathogenicity island protein Cag12 SWIB PF02201.18 CBK21391.2 - 0.13 12.2 1.8 32 4.5 0.1 3.4 3 0 0 3 3 3 0 SWIB/MDM2 domain DUF4143 PF13635.6 CBK21391.2 - 0.35 11.0 6.6 4.8 7.4 0.2 3.8 4 0 0 4 4 4 0 Domain of unknown function (DUF4143) EnY2 PF10163.9 CBK21391.2 - 0.4 11.1 5.8 11 6.5 0.4 2.9 2 0 0 2 2 2 0 Transcription factor e(y)2 CaKB PF03185.15 CBK21391.2 - 1.8 8.2 16.8 5.1 6.7 2.2 3.1 1 1 2 3 3 3 0 Calcium-activated potassium channel, beta subunit DUF2525 PF10733.9 CBK21391.2 - 8 6.8 9.1 36 4.7 0.3 4.2 4 0 0 4 4 4 0 Protein of unknown function (DUF2525) Pyr_redox_2 PF07992.14 CBK21392.2 - 1.1e-72 244.7 4.4 1.8e-72 244.0 4.4 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 CBK21392.2 - 1.6e-38 131.4 0.1 3.6e-38 130.2 0.1 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 CBK21392.2 - 1.1e-19 70.8 8.3 3e-17 62.9 0.8 2.9 3 0 0 3 3 2 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 CBK21392.2 - 1.1e-11 44.5 3.1 1.6e-10 40.6 0.6 2.2 2 0 0 2 2 2 1 Glucose inhibited division protein A FAD_oxidored PF12831.7 CBK21392.2 - 4.8e-11 42.7 8.2 5.4e-11 42.5 0.4 2.8 2 1 1 3 3 3 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 CBK21392.2 - 7.5e-10 38.5 3.1 3.7e-06 26.4 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 CBK21392.2 - 7.1e-07 28.6 2.5 7.1e-07 28.6 2.5 3.8 4 1 1 5 5 5 1 FAD binding domain HI0933_like PF03486.14 CBK21392.2 - 9.8e-07 27.8 9.8 0.00046 19.0 1.2 3.9 4 0 0 4 4 4 2 HI0933-like protein NAD_binding_8 PF13450.6 CBK21392.2 - 2.9e-06 27.4 7.0 0.00041 20.5 2.2 2.6 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 CBK21392.2 - 7.1e-05 22.2 13.7 0.0083 15.4 1.0 3.3 2 1 1 3 3 3 2 FAD binding domain K_oxygenase PF13434.6 CBK21392.2 - 7.7e-05 22.0 1.6 0.0099 15.1 0.0 2.6 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.17 CBK21392.2 - 8e-05 22.0 1.5 0.00013 21.3 0.2 1.9 2 0 0 2 2 2 1 Thi4 family DAO PF01266.24 CBK21392.2 - 0.0021 17.7 0.3 0.0021 17.7 0.3 4.1 2 2 0 4 4 4 2 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 CBK21392.2 - 0.013 14.8 11.8 0.072 12.4 0.9 3.1 3 2 1 4 4 4 0 Alanine dehydrogenase/PNT, C-terminal domain Lycopene_cycl PF05834.12 CBK21392.2 - 8.9 5.2 9.6 1.6 7.7 1.0 3.2 2 2 1 3 3 3 0 Lycopene cyclase protein Spec3 PF15795.5 CBK21394.2 - 0.00081 19.9 9.2 0.0029 18.1 9.2 1.8 1 1 0 1 1 1 1 Ectodermal ciliogenesis protein PXPV PF12778.7 CBK21394.2 - 0.0062 16.4 10.7 0.0062 16.4 10.7 3.9 1 1 3 4 4 4 2 PXPV repeat (3 copies) Cuticle_3 PF11018.8 CBK21394.2 - 0.025 14.8 7.7 0.034 14.4 7.7 1.1 1 0 0 1 1 1 0 Pupal cuticle protein C1 Spec3 PF15795.5 CBK21395.2 - 0.00043 20.8 12.8 0.024 15.2 12.8 2.1 1 1 0 1 1 1 1 Ectodermal ciliogenesis protein TCRP1 PF14944.6 CBK21395.2 - 1.8 8.5 13.4 2.7 7.9 13.4 1.3 1 0 0 1 1 1 0 Tongue Cancer Chemotherapy Resistant Protein 1 DUF3449 PF11931.8 CBK21396.2 - 1.3e-69 233.7 5.2 1.3e-69 233.7 5.2 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF3449) SF3A3 PF16837.5 CBK21396.2 - 8.5e-26 90.3 5.4 8.5e-26 90.3 5.4 2.1 2 1 0 2 2 2 1 Pre-mRNA-splicing factor SF3A3, of SF3a complex, Prp9 Telomere_Sde2_2 PF13297.6 CBK21396.2 - 3.8e-15 55.3 0.0 1.2e-14 53.7 0.0 1.9 1 0 0 1 1 1 1 Telomere stability C-terminal SF3a60_bindingd PF12108.8 CBK21396.2 - 9.9e-11 41.3 0.1 3.4e-10 39.6 0.1 2.0 1 0 0 1 1 1 1 Splicing factor SF3a60 binding domain Med11 PF10280.9 CBK21396.2 - 0.029 14.8 0.8 0.078 13.4 0.2 2.1 2 0 0 2 2 2 0 Mediator complex protein IBB PF01749.20 CBK21396.2 - 0.065 13.7 0.2 0.065 13.7 0.2 2.4 2 0 0 2 2 2 0 Importin beta binding domain Latarcin PF10279.9 CBK21396.2 - 0.11 13.0 8.7 10 6.6 0.0 4.8 3 3 1 4 4 4 0 Latarcin precursor Desulfoferrod_N PF06397.12 CBK21396.2 - 0.25 11.0 0.7 0.5 10.0 0.7 1.4 1 0 0 1 1 1 0 Desulfoferrodoxin, N-terminal domain PTS_EIIC_2 PF13303.6 CBK21397.2 - 6.5e-103 344.2 47.2 7.4e-103 344.0 47.2 1.0 1 0 0 1 1 1 1 Phosphotransferase system, EIIC UME PF08064.13 CBK21398.2 - 0.099 12.6 0.0 0.11 12.5 0.0 1.1 1 0 0 1 1 1 0 UME (NUC010) domain DUF2347 PF09804.9 CBK21399.2 - 0.13 11.8 0.0 0.16 11.5 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2347) PP2C PF00481.21 CBK21400.2 - 0.0012 18.6 0.0 0.0012 18.6 0.0 1.0 1 0 0 1 1 1 1 Protein phosphatase 2C Glyco_trans_4_5 PF16994.5 CBK21400.2 - 0.0079 15.8 0.1 0.009 15.6 0.1 1.0 1 0 0 1 1 1 1 Glycosyl-transferase family 4 Dimer_Tnp_hAT PF05699.14 CBK21400.2 - 0.045 13.6 0.0 0.056 13.2 0.0 1.2 1 0 0 1 1 1 0 hAT family C-terminal dimerisation region Nitroreductase PF00881.24 CBK21401.2 - 1.6e-26 93.4 0.0 8.3e-26 91.0 0.0 1.9 1 1 0 1 1 1 1 Nitroreductase family TM1586_NiRdase PF14512.6 CBK21401.2 - 7.9e-11 41.9 0.0 5e-05 23.0 0.0 3.1 2 1 1 3 3 3 3 Putative TM nitroreductase ATP_bind_1 PF03029.17 CBK21402.2 - 1.3e-66 224.9 0.2 1.3e-64 218.3 0.0 2.0 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein CLP1_P PF16575.5 CBK21402.2 - 2.8e-05 24.0 0.0 5e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop KTI12 PF08433.10 CBK21402.2 - 0.0029 17.1 0.0 0.0049 16.4 0.0 1.3 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_18 PF13238.6 CBK21402.2 - 0.0086 16.6 0.0 0.026 15.1 0.0 1.9 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 CBK21402.2 - 0.017 15.5 0.0 0.15 12.5 0.0 2.3 2 0 0 2 2 2 0 RNA helicase MeaB PF03308.16 CBK21402.2 - 0.019 14.0 0.0 0.036 13.1 0.0 1.3 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB PBP1_TM PF14812.6 CBK21402.2 - 0.02 15.3 1.6 0.027 14.8 0.6 1.7 1 1 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal T2SSE PF00437.20 CBK21402.2 - 0.027 13.5 0.0 0.043 12.9 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_17 PF13207.6 CBK21402.2 - 0.047 14.1 0.0 0.1 13.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 CBK21402.2 - 0.06 13.1 0.0 0.1 12.3 0.0 1.5 1 1 0 1 1 1 0 AAA domain CbiA PF01656.23 CBK21402.2 - 0.068 13.2 0.0 0.093 12.8 0.0 1.5 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 CBK21402.2 - 0.12 12.3 0.0 0.29 11.0 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_24 PF13479.6 CBK21402.2 - 0.16 11.7 0.0 0.22 11.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 CBK21402.2 - 0.18 12.0 0.0 0.42 10.8 0.0 1.7 2 0 0 2 2 2 0 AAA domain Peptidase_S8 PF00082.22 CBK21403.2 - 3.6e-41 141.4 0.1 4.6e-41 141.0 0.1 1.1 1 0 0 1 1 1 1 Subtilase family HSP20 PF00011.21 CBK21404.2 - 1.5e-26 92.5 1.4 1.8e-26 92.3 1.4 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 CBK21404.2 - 1.5e-12 46.9 0.0 2.4e-12 46.2 0.0 1.4 1 0 0 1 1 1 1 HSP20-like domain found in ArsA Glyco_tranf_2_3 PF13641.6 CBK21405.2 - 0.0075 16.2 0.0 0.013 15.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 HSP70 PF00012.20 CBK21406.2 - 1.9e-27 95.7 2.6 1.9e-23 82.5 0.0 2.6 2 1 1 3 3 3 2 Hsp70 protein TPR_1 PF00515.28 CBK21406.2 - 3.4e-11 42.4 2.1 0.0019 17.9 0.0 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 CBK21406.2 - 1.7e-09 37.1 3.8 0.0074 16.3 0.0 4.2 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_19 PF14559.6 CBK21406.2 - 1.5e-07 31.8 5.3 0.00041 20.8 0.0 4.0 3 1 1 4 4 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 CBK21406.2 - 1.1e-05 25.3 1.8 0.12 12.6 0.0 4.0 3 0 0 3 3 3 1 Tetratricopeptide repeat ANAPC3 PF12895.7 CBK21406.2 - 0.00014 22.0 0.8 0.00034 20.8 0.8 1.8 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 FGGY_C PF02782.16 CBK21406.2 - 0.00016 21.5 0.2 0.00033 20.5 0.2 1.4 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain TPR_6 PF13174.6 CBK21406.2 - 0.00024 21.6 2.7 0.96 10.2 0.0 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 CBK21406.2 - 0.00028 20.9 0.3 0.56 10.3 0.0 3.8 2 1 1 3 3 3 1 Fis1 C-terminal tetratricopeptide repeat TPR_9 PF13371.6 CBK21406.2 - 0.00063 19.8 0.7 0.002 18.2 0.0 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.6 CBK21406.2 - 0.0064 16.4 0.7 0.053 13.6 0.0 3.0 4 0 0 4 4 2 1 Tetratricopeptide repeat TPR_17 PF13431.6 CBK21406.2 - 0.013 15.8 0.2 0.051 14.0 0.0 2.2 2 0 0 2 2 1 0 Tetratricopeptide repeat MIT PF04212.18 CBK21406.2 - 0.017 15.2 4.4 0.18 11.9 0.2 3.6 3 0 0 3 3 3 0 MIT (microtubule interacting and transport) domain SIP PF04954.13 CBK21406.2 - 0.027 15.0 0.4 0.069 13.7 0.4 1.7 1 0 0 1 1 1 0 Siderophore-interacting protein TPR_16 PF13432.6 CBK21406.2 - 0.04 14.6 0.5 0.86 10.3 0.0 3.3 3 1 0 3 3 3 0 Tetratricopeptide repeat DUF3045 PF11243.8 CBK21406.2 - 0.056 13.6 0.2 0.13 12.4 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3045) MreB_Mbl PF06723.13 CBK21406.2 - 0.11 11.3 0.0 0.18 10.6 0.0 1.3 1 0 0 1 1 1 0 MreB/Mbl protein Ndufs5 PF10200.9 CBK21407.2 - 0.0015 18.8 1.6 0.0019 18.4 1.6 1.3 1 0 0 1 1 1 1 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa CHCH PF06747.13 CBK21407.2 - 0.0093 16.1 2.6 0.034 14.3 0.3 2.3 2 0 0 2 2 2 1 CHCH domain PRE_C2HC PF07530.11 CBK21407.2 - 0.027 14.6 0.1 0.038 14.1 0.1 1.2 1 0 0 1 1 1 0 Associated with zinc fingers DUF3128 PF11326.8 CBK21407.2 - 2.3 8.6 10.6 1.6e+02 2.7 10.6 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF3128) adh_short PF00106.25 CBK21408.2 - 1.4e-11 44.2 1.6 1.2e-10 41.2 1.6 2.0 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CBK21408.2 - 1.2e-09 38.1 0.0 6.7e-09 35.6 0.0 1.8 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Coatomer_E PF04733.14 CBK21410.2 - 4.4e-11 42.7 0.0 4.4e-11 42.7 0.0 1.1 1 0 0 1 1 1 1 Coatomer epsilon subunit Piezo_RRas_bdg PF12166.8 CBK21411.2 - 1.6e-41 143.0 5.4 2e-41 142.7 5.4 1.0 1 0 0 1 1 1 1 Piezo non-specific cation channel, R-Ras-binding domain RRM_1 PF00076.22 CBK21412.2 - 2.6e-33 113.6 0.0 3.1e-21 75.0 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF2052 PF09747.9 CBK21412.2 - 0.021 15.0 37.9 0.044 13.9 37.9 1.6 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) SprA-related PF12118.8 CBK21412.2 - 0.2 10.7 23.7 0.23 10.5 23.7 1.2 1 0 0 1 1 1 0 SprA-related family Nop14 PF04147.12 CBK21412.2 - 1.4 7.0 50.1 1.8 6.6 50.1 1.1 1 0 0 1 1 1 0 Nop14-like family EF-hand_1 PF00036.32 CBK21413.2 - 7.1e-11 40.9 2.3 0.00045 19.6 0.1 4.0 3 1 2 5 5 5 2 EF hand EF-hand_6 PF13405.6 CBK21413.2 - 3.4e-10 39.0 3.8 0.00068 19.4 0.0 3.9 3 1 1 4 4 4 2 EF-hand domain EF-hand_7 PF13499.6 CBK21413.2 - 3.3e-07 30.7 0.2 3.3e-07 30.7 0.2 2.9 1 1 1 2 2 2 1 EF-hand domain pair EF-hand_8 PF13833.6 CBK21413.2 - 4.5e-06 26.4 1.0 0.0019 18.0 0.3 2.7 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 CBK21413.2 - 1.2e-05 24.5 4.7 0.067 12.7 0.0 3.6 3 0 0 3 3 3 2 EF hand SPARC_Ca_bdg PF10591.9 CBK21413.2 - 0.0053 17.1 5.1 0.035 14.4 5.1 2.3 1 1 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region MLANA PF14991.6 CBK21413.2 - 0.055 13.7 0.0 0.13 12.6 0.0 1.7 2 0 0 2 2 2 0 Protein melan-A TFIIB PF00382.19 CBK21415.2 - 2e-33 114.2 1.3 1.4e-16 60.3 0.0 3.1 2 1 1 3 3 3 3 Transcription factor TFIIB repeat BRF1 PF07741.13 CBK21415.2 - 4.6e-20 71.8 6.9 4.6e-20 71.8 6.9 1.9 1 1 1 2 2 2 1 Brf1-like TBP-binding domain TF_Zn_Ribbon PF08271.12 CBK21415.2 - 4e-07 29.4 4.4 4e-07 29.4 4.4 2.3 3 0 0 3 3 3 1 TFIIB zinc-binding Cyclin_N PF00134.23 CBK21415.2 - 6.9e-05 22.6 0.3 0.12 12.1 0.1 2.7 2 0 0 2 2 2 2 Cyclin, N-terminal domain FKBP_C PF00254.28 CBK21417.2 - 8.7e-29 99.7 0.0 1.1e-28 99.4 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Sad1_UNC PF07738.13 CBK21418.2 - 9.6e-05 22.4 0.0 0.00025 21.0 0.0 1.6 2 0 0 2 2 2 1 Sad1 / UNC-like C-terminal FPP PF05911.11 CBK21418.2 - 0.011 14.0 0.8 0.014 13.6 0.8 1.1 1 0 0 1 1 1 0 Filament-like plant protein, long coiled-coil YojJ PF10372.9 CBK21418.2 - 0.014 15.5 0.9 0.042 13.9 0.4 2.0 1 1 0 1 1 1 0 Bacterial membrane-spanning protein N-terminus DUF1664 PF07889.12 CBK21418.2 - 0.034 14.2 2.0 0.33 11.0 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Asparaginase PF00710.20 CBK21418.2 - 0.038 13.5 0.1 0.064 12.8 0.1 1.4 1 1 0 1 1 1 0 Asparaginase, N-terminal DUF4472 PF14739.6 CBK21418.2 - 0.041 14.6 0.4 0.076 13.7 0.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4472) BLOC1_2 PF10046.9 CBK21418.2 - 0.06 13.7 2.6 0.4 11.0 0.5 2.7 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Fib_alpha PF08702.10 CBK21418.2 - 1.3 9.3 3.4 2.7 8.2 3.4 1.6 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family GAS PF13851.6 CBK21419.2 - 0.0034 16.7 14.4 0.0034 16.7 14.4 1.9 2 0 0 2 2 2 1 Growth-arrest specific micro-tubule binding Macoilin PF09726.9 CBK21419.2 - 0.0044 15.7 4.2 0.0047 15.6 4.2 1.3 1 0 0 1 1 1 1 Macoilin family Apt1 PF10351.9 CBK21419.2 - 0.012 14.5 5.5 0.015 14.2 5.5 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain TMF_TATA_bd PF12325.8 CBK21419.2 - 0.021 15.0 11.4 0.021 15.0 11.4 1.9 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding YtxH PF12732.7 CBK21419.2 - 0.028 14.9 4.4 0.33 11.5 4.4 2.2 1 1 0 1 1 1 0 YtxH-like protein XhlA PF10779.9 CBK21419.2 - 0.032 14.4 0.8 0.032 14.4 0.8 2.9 2 1 0 2 2 2 0 Haemolysin XhlA DUF4407 PF14362.6 CBK21419.2 - 0.16 11.3 3.3 0.19 11.1 3.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) PepSY_TM_like_2 PF16357.5 CBK21419.2 - 0.19 11.7 2.7 0.16 11.9 1.4 1.5 1 1 1 2 2 2 0 Putative PepSY_TM-like CortBP2 PF09727.9 CBK21419.2 - 0.28 11.1 19.8 0.061 13.2 15.1 1.9 2 0 0 2 2 2 0 Cortactin-binding protein-2 CENP-H PF05837.12 CBK21419.2 - 0.38 11.2 14.1 0.085 13.3 9.9 1.9 2 0 0 2 2 2 0 Centromere protein H (CENP-H) DivIVA PF05103.13 CBK21419.2 - 0.66 10.1 13.6 0.33 11.0 10.1 2.1 2 1 0 2 2 2 0 DivIVA protein V_ATPase_I PF01496.19 CBK21419.2 - 0.77 7.6 5.7 0.78 7.6 5.7 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DivIC PF04977.15 CBK21419.2 - 1.1 9.1 23.7 0.22 11.3 6.8 3.1 2 1 1 3 3 3 0 Septum formation initiator UPF0242 PF06785.11 CBK21419.2 - 3.4 7.7 14.2 0.38 10.8 9.5 1.7 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Tho2 PF11262.8 CBK21419.2 - 3.6 6.7 10.7 0.46 9.6 5.5 1.9 2 0 0 2 2 2 0 Transcription factor/nuclear export subunit protein 2 DUF724 PF05266.14 CBK21419.2 - 5.1 6.9 13.3 0.83 9.4 9.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF724) APG6_N PF17675.1 CBK21419.2 - 5.1 7.6 19.6 1.9 9.0 14.0 2.2 2 1 0 2 2 2 0 Apg6 coiled-coil region TRAP-gamma PF07074.12 CBK21419.2 - 8.2 6.0 11.1 1.6 8.3 7.1 1.8 2 0 0 2 2 2 0 Translocon-associated protein, gamma subunit (TRAP-gamma) RCC1 PF00415.18 CBK21420.2 - 2.1e-50 169.1 14.3 1.5e-13 51.1 0.9 5.5 5 0 0 5 5 5 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 CBK21420.2 - 2.2e-23 81.5 31.2 3.6e-09 36.2 0.7 4.5 4 0 0 4 4 4 4 Regulator of chromosome condensation (RCC1) repeat Ala_racemase_N PF01168.20 CBK21420.2 - 7.4e-17 61.7 0.0 1.1e-16 61.2 0.0 1.2 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain MEDS PF14417.6 CBK21421.2 - 0.0021 17.9 0.1 0.0023 17.8 0.1 1.1 1 0 0 1 1 1 1 MEDS: MEthanogen/methylotroph, DcmR Sensory domain Sld5 PF05916.11 CBK21421.2 - 0.0042 17.5 0.3 0.0051 17.3 0.3 1.3 1 0 0 1 1 1 1 GINS complex protein Pox_int_trans PF05718.12 CBK21421.2 - 0.028 13.1 0.2 0.037 12.7 0.2 1.3 1 1 0 1 1 1 0 Poxvirus intermediate transcription factor MCM PF00493.23 CBK21422.2 - 1.9e-94 314.9 0.0 2.6e-94 314.5 0.0 1.2 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 CBK21422.2 - 1.8e-29 102.1 0.0 3.8e-29 101.1 0.0 1.5 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 CBK21422.2 - 5.5e-25 87.6 0.6 1.2e-24 86.6 0.6 1.6 1 0 0 1 1 1 1 MCM AAA-lid domain Mg_chelatase PF01078.21 CBK21422.2 - 1.5e-09 37.5 0.1 2.9e-06 26.8 0.0 2.3 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 CBK21422.2 - 0.00049 20.0 0.0 0.00095 19.0 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA PF00004.29 CBK21422.2 - 0.0011 19.4 0.0 0.0025 18.2 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 CBK21422.2 - 0.0014 18.6 0.0 0.0047 16.9 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.26 CBK21422.2 - 0.0018 18.0 0.0 0.012 15.3 0.0 2.0 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_16 PF13191.6 CBK21422.2 - 0.11 12.8 0.1 0.9 9.9 0.0 2.2 1 1 1 2 2 2 0 AAA ATPase domain Ribosomal_L5_C PF00673.21 CBK21423.2 - 1.5e-20 73.1 0.0 2.4e-20 72.5 0.0 1.3 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.19 CBK21423.2 - 1.9e-18 66.5 0.3 3.8e-18 65.6 0.1 1.6 2 0 0 2 2 2 1 Ribosomal protein L5 HTH_ABP1_N PF18107.1 CBK21423.2 - 0.013 15.2 0.4 0.071 12.8 0.1 2.0 2 0 0 2 2 2 0 Fission yeast centromere protein N-terminal domain DUF1681 PF07933.14 CBK21424.2 - 1.2e-33 115.9 0.1 1.8e-33 115.3 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1681) SMN PF06003.12 CBK21424.2 - 0.0053 16.1 0.6 0.0068 15.7 0.6 1.1 1 0 0 1 1 1 1 Survival motor neuron protein (SMN) SWIRM-assoc_2 PF16496.5 CBK21424.2 - 0.023 13.6 2.3 0.025 13.4 2.3 1.1 1 0 0 1 1 1 0 SWIRM-associated domain at the N-terminal DUF4813 PF16072.5 CBK21424.2 - 0.62 9.7 6.9 0.79 9.3 6.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4813) AMP-binding PF00501.28 CBK21425.2 - 1e-72 245.1 0.0 1.7e-72 244.3 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 CBK21425.2 - 0.00026 21.9 0.1 0.00057 20.8 0.1 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Complex1_LYR PF05347.15 CBK21426.2 - 2.9e-05 24.0 0.1 4.1e-05 23.6 0.1 1.2 1 0 0 1 1 1 1 Complex 1 protein (LYR family) RRM_1 PF00076.22 CBK21427.2 - 4.8e-11 42.3 0.0 0.00036 20.3 0.0 2.8 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 CBK21427.2 - 0.00088 19.1 0.0 0.49 10.3 0.0 3.3 3 1 0 3 3 3 1 Occluded RNA-recognition motif RSB_motif PF16294.5 CBK21427.2 - 0.015 15.5 4.2 0.024 14.9 4.2 1.3 1 0 0 1 1 1 0 RNSP1-SAP18 binding (RSB) motif Talin_middle PF09141.10 CBK21427.2 - 0.067 13.2 0.1 2.2 8.3 0.1 2.4 2 0 0 2 2 2 0 Talin, middle domain YihI PF04220.12 CBK21427.2 - 0.71 9.6 0.0 0.71 9.6 0.0 2.0 2 0 0 2 2 2 0 Der GTPase activator (YihI) Corona_nucleoca PF00937.18 CBK21427.2 - 8.5 5.3 8.2 14 4.6 8.2 1.3 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein Ribosomal_S15 PF00312.22 CBK21428.2 - 1.1e-30 105.6 3.3 1.4e-30 105.3 3.3 1.1 1 0 0 1 1 1 1 Ribosomal protein S15 BET PF17035.5 CBK21428.2 - 0.1 12.8 0.0 0.32 11.2 0.0 1.8 1 1 1 2 2 2 0 Bromodomain extra-terminal - transcription regulation DivIC PF04977.15 CBK21429.2 - 0.0065 16.2 0.4 0.0065 16.2 0.4 5.9 3 1 3 6 6 6 1 Septum formation initiator MLANA PF14991.6 CBK21429.2 - 0.035 14.4 1.6 0.14 12.5 0.0 2.6 2 1 0 2 2 2 0 Protein melan-A Mei5_like PF17021.5 CBK21429.2 - 0.038 14.0 6.8 0.088 12.9 6.4 1.8 1 1 0 1 1 1 0 Putative double-strand recombination repair-like Laminin_EGF PF00053.24 CBK21429.2 - 0.062 13.4 1.8 0.14 12.4 1.8 1.5 1 0 0 1 1 1 0 Laminin EGF domain SPOUT_MTase_2 PF14419.6 CBK21429.2 - 0.22 10.9 2.0 0.41 10.0 2.0 1.4 1 0 0 1 1 1 0 AF2226-like SPOUT RNA Methylase fused to THUMP Phage_GP20 PF06810.11 CBK21429.2 - 3.3 7.5 22.3 0.084 12.7 9.0 3.3 1 1 2 3 3 3 0 Phage minor structural protein GP20 SF1-HH PF16275.5 CBK21429.2 - 8.9 6.7 9.4 0.44 10.9 1.8 2.4 2 1 0 2 2 2 0 Splicing factor 1 helix-hairpin domain eRF1_2 PF03464.15 CBK21430.2 - 1.4e-40 138.7 0.0 2.1e-40 138.1 0.0 1.3 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.15 CBK21430.2 - 3.9e-40 136.9 0.1 7.8e-40 135.9 0.1 1.5 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_1 PF03463.15 CBK21430.2 - 3e-19 69.3 0.0 4.8e-19 68.6 0.0 1.3 1 0 0 1 1 1 1 eRF1 domain 1 acVLRF1 PF18859.1 CBK21430.2 - 2.3e-09 37.6 0.0 3.6e-09 37.0 0.0 1.3 1 0 0 1 1 1 1 Actinobacteria/chloroflexi VLRF1 release factor baeRF_family10 PF18854.1 CBK21430.2 - 3e-08 34.0 0.0 4.7e-08 33.4 0.0 1.3 1 0 0 1 1 1 1 Bacterial archaeo-eukaryotic release factor family 10 Glyco_tran_28_C PF04101.16 CBK21431.2 - 2.8e-26 92.5 0.1 3.3e-26 92.3 0.1 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain DNA_pol_B_2 PF03175.13 CBK21433.2 - 1.8e-19 70.0 13.7 8.8e-19 67.7 13.7 1.9 1 1 0 1 1 1 1 DNA polymerase type B, organellar and viral Glyco_tran_28_C PF04101.16 CBK21434.2 - 2.8e-26 92.5 0.1 3.3e-26 92.3 0.1 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Pkinase PF00069.25 CBK21435.2 - 3.3e-36 125.0 0.0 4.7e-36 124.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBK21435.2 - 1.8e-18 66.8 0.0 2.7e-18 66.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 CBK21435.2 - 0.00097 19.1 0.1 0.0022 18.0 0.0 1.5 2 0 0 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.22 CBK21435.2 - 0.0077 15.9 0.1 0.016 14.8 0.0 1.5 2 0 0 2 2 2 1 RIO1 family Kdo PF06293.14 CBK21435.2 - 0.022 14.1 0.3 0.055 12.8 0.0 1.7 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 CBK21435.2 - 0.023 14.0 0.1 0.065 12.5 0.0 1.7 2 0 0 2 2 2 0 Kinase-like Pkinase_fungal PF17667.1 CBK21435.2 - 0.029 13.1 0.0 0.041 12.7 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Choline_kinase PF01633.20 CBK21435.2 - 0.098 12.2 0.0 0.18 11.3 0.0 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase Ribosomal_L17 PF01196.19 CBK21436.2 - 3.2e-19 69.6 1.5 4.6e-19 69.1 1.5 1.1 1 0 0 1 1 1 1 Ribosomal protein L17 Prefoldin_3 PF13758.6 CBK21436.2 - 0.00076 19.5 0.5 0.00087 19.3 0.5 1.1 1 0 0 1 1 1 1 Prefoldin subunit TetR PF13972.6 CBK21436.2 - 0.045 13.5 0.1 0.057 13.1 0.1 1.3 1 0 0 1 1 1 0 Bacterial transcriptional repressor Nrap_D5 PF17406.2 CBK21436.2 - 0.13 12.0 0.5 0.14 11.9 0.5 1.1 1 0 0 1 1 1 0 Nrap protein PAP/OAS1-like domain 5 Methyltransf_25 PF13649.6 CBK21438.2 - 7.7e-06 26.5 0.0 1.1e-05 26.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CBK21438.2 - 8.7e-05 23.1 0.0 0.00013 22.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 CBK21438.2 - 0.00033 20.1 0.0 0.00048 19.5 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 CBK21438.2 - 0.0057 17.4 0.0 0.0083 16.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain RNA_pol_N PF01194.17 CBK21439.2 - 1.5e-30 105.2 0.7 2e-30 104.8 0.7 1.2 1 0 0 1 1 1 1 RNA polymerases N / 8 kDa subunit DUF2053 PF09767.9 CBK21440.2 - 6.7e-36 123.9 9.8 1.2e-35 123.0 9.8 1.4 1 0 0 1 1 1 1 Predicted membrane protein (DUF2053) E1-E2_ATPase PF00122.20 CBK21441.2 - 4e-53 179.6 0.8 1.6e-51 174.4 0.0 2.7 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 CBK21441.2 - 1.4e-49 168.3 0.7 3.3e-49 167.1 0.7 1.7 1 0 0 1 1 1 1 Cation transporting ATPase, C-terminus Cation_ATPase PF13246.6 CBK21441.2 - 5.5e-22 77.7 0.0 9.7e-22 76.9 0.0 1.4 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 CBK21441.2 - 2e-19 69.0 0.3 8.9e-19 67.0 0.0 2.2 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase PF00702.26 CBK21441.2 - 4.1e-19 69.7 3.4 1.1e-18 68.4 1.2 2.8 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 CBK21441.2 - 9e-06 25.6 0.4 0.00046 20.0 0.4 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 CBK21441.2 - 0.012 16.1 0.0 0.03 14.7 0.0 1.7 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase PPR_2 PF13041.6 CBK21442.2 - 9.6e-37 125.0 0.1 4.1e-06 26.9 0.0 9.4 3 3 6 9 9 9 8 PPR repeat family PPR PF01535.20 CBK21442.2 - 8.1e-25 85.3 6.0 0.0041 17.3 0.0 9.8 10 1 0 10 10 10 5 PPR repeat PPR_3 PF13812.6 CBK21442.2 - 2e-22 79.0 0.1 3.2e-06 27.1 0.0 6.5 4 2 3 7 7 7 6 Pentatricopeptide repeat domain PPR_1 PF12854.7 CBK21442.2 - 1.9e-17 62.6 0.0 0.00015 21.4 0.0 6.1 7 0 0 7 7 7 4 PPR repeat PPR_long PF17177.4 CBK21442.2 - 2.8e-16 59.5 0.0 8.5e-05 22.0 0.0 3.3 2 1 1 3 3 3 3 Pentacotripeptide-repeat region of PRORP Clathrin PF00637.20 CBK21442.2 - 0.035 14.0 0.1 2.9 7.7 0.0 2.9 2 1 0 2 2 2 0 Region in Clathrin and VPS Ank_2 PF12796.7 CBK21443.2 - 1.1e-30 106.0 5.6 5.4e-11 42.9 0.1 3.5 1 1 2 4 4 4 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 CBK21443.2 - 1.6e-19 69.7 8.2 5.4e-09 36.1 0.1 4.2 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 CBK21443.2 - 1.9e-19 67.7 5.6 0.0012 19.1 0.1 6.5 7 0 0 7 7 7 4 Ankyrin repeat Ank PF00023.30 CBK21443.2 - 6.8e-19 67.4 7.5 7.5e-05 23.0 0.2 6.0 6 0 0 6 6 6 4 Ankyrin repeat Ank_4 PF13637.6 CBK21443.2 - 1.6e-16 60.4 2.3 3.6e-07 30.6 0.0 4.3 3 1 1 4 4 4 3 Ankyrin repeats (many copies) cwf18 PF08315.12 CBK21444.2 - 3.6e-15 56.8 8.8 5.6e-15 56.2 8.8 1.3 1 0 0 1 1 1 1 cwf18 pre-mRNA splicing factor ApbA PF02558.16 CBK21444.2 - 0.1 12.3 0.2 0.14 11.8 0.2 1.1 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Peptidase_S8 PF00082.22 CBK21445.2 - 5.2e-44 150.7 0.2 6.4e-44 150.4 0.2 1.1 1 0 0 1 1 1 1 Subtilase family AA_permease_2 PF13520.6 CBK21446.2 - 0.0014 17.6 0.1 0.0014 17.6 0.1 1.2 1 0 0 1 1 1 1 Amino acid permease DUF4448 PF14610.6 CBK21446.2 - 0.066 13.0 0.4 0.08 12.7 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) Pox_EPC_I2-L1 PF12575.8 CBK21446.2 - 0.11 12.8 1.9 0.96 9.7 0.2 2.3 2 0 0 2 2 2 0 Poxvirus entry protein complex L1 and I2 Amnionless PF14828.6 CBK21446.2 - 0.12 11.1 0.1 0.14 10.9 0.1 1.1 1 0 0 1 1 1 0 Amnionless Orf78 PF06024.12 CBK21446.2 - 0.24 11.7 3.0 0.5 10.7 3.1 1.8 1 1 0 1 1 1 0 Orf78 (ac78) DUF5385 PF17359.2 CBK21446.2 - 0.62 9.6 3.2 0.97 8.9 3.2 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5385) Insulin_TMD PF17870.1 CBK21446.2 - 0.64 10.1 8.7 1.5 9.0 5.1 2.4 2 0 0 2 2 2 0 Insulin receptor trans-membrane segment FeoB_associated PF12669.7 CBK21446.2 - 1.1 9.7 5.9 2.7 8.5 5.9 1.7 1 1 0 1 1 1 0 FeoB-associated Cys-rich membrane protein CD34_antigen PF06365.12 CBK21446.2 - 1.1 8.7 5.1 0.37 10.3 1.6 1.8 1 1 1 2 2 2 0 CD34/Podocalyxin family Shisa PF13908.6 CBK21446.2 - 1.3 9.2 6.2 6.1 7.0 6.4 1.9 1 1 1 2 2 2 0 Wnt and FGF inhibitory regulator EphA2_TM PF14575.6 CBK21446.2 - 2.4 9.1 4.6 5.7 7.9 4.6 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain MscL PF01741.18 CBK21447.2 - 0.048 13.9 0.0 0.079 13.3 0.0 1.3 1 0 0 1 1 1 0 Large-conductance mechanosensitive channel, MscL Proteasome PF00227.26 CBK21448.2 - 2.6e-41 141.2 2.0 5.4e-41 140.2 2.0 1.5 1 1 0 1 1 1 1 Proteasome subunit Motile_Sperm PF00635.26 CBK21449.2 - 0.00048 19.9 0.0 0.00087 19.1 0.0 1.4 1 0 0 1 1 1 1 MSP (Major sperm protein) domain ASH PF15780.5 CBK21449.2 - 0.0049 17.1 0.0 0.0084 16.3 0.0 1.3 1 0 0 1 1 1 1 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin F-box_5 PF18511.1 CBK21449.2 - 0.027 14.0 0.8 0.065 12.8 0.8 1.6 1 0 0 1 1 1 0 F-box F-box-like PF12937.7 CBK21449.2 - 0.081 12.8 0.1 0.28 11.1 0.1 1.9 1 0 0 1 1 1 0 F-box-like eIF-1a PF01176.19 CBK21450.2 - 1.8e-23 82.1 0.4 2.7e-23 81.5 0.4 1.3 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 RsgA_N PF16745.5 CBK21450.2 - 0.092 12.5 0.5 0.092 12.5 0.5 1.8 2 0 0 2 2 2 0 RsgA N-terminal domain HSBP1 PF06825.12 CBK21451.2 - 4e-05 23.4 1.2 0.00093 19.0 0.1 2.1 1 1 1 2 2 2 2 Heat shock factor binding protein 1 bZIP_2 PF07716.15 CBK21451.2 - 0.056 13.5 5.7 0.69 10.0 2.7 2.2 1 1 1 2 2 2 0 Basic region leucine zipper bZIP_1 PF00170.21 CBK21451.2 - 0.15 12.2 5.5 2.1 8.5 2.7 2.2 1 1 1 2 2 2 0 bZIP transcription factor Ribosomal_L29 PF00831.23 CBK21451.2 - 0.29 11.1 6.0 0.15 12.0 2.5 1.9 1 1 1 2 2 2 0 Ribosomal L29 protein HSBP1 PF06825.12 CBK21452.2 - 7.1e-06 25.8 1.8 7.3e-06 25.7 1.8 1.1 1 0 0 1 1 1 1 Heat shock factor binding protein 1 APG6_N PF17675.1 CBK21453.2 - 0.019 15.5 19.5 0.31 11.6 7.0 2.1 2 0 0 2 2 2 0 Apg6 coiled-coil region VWA_3 PF13768.6 CBK21453.2 - 0.064 13.2 0.8 0.1 12.5 0.2 1.6 1 1 1 2 2 2 0 von Willebrand factor type A domain Methyltransf_24 PF13578.6 CBK21453.2 - 0.14 13.2 0.0 0.26 12.3 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Phlebovirus_NSM PF07246.11 CBK21453.2 - 0.19 11.1 10.0 0.14 11.5 1.1 2.0 2 0 0 2 2 2 0 Phlebovirus nonstructural protein NS-M Spc24 PF08286.11 CBK21453.2 - 0.48 10.7 12.0 0.16 12.2 2.9 2.3 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 CLZ PF16526.5 CBK21453.2 - 0.6 10.5 14.3 1.1 9.7 2.1 2.6 3 0 0 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels FUSC PF04632.12 CBK21453.2 - 1.4 7.3 4.7 1.3 7.5 3.8 1.3 1 1 0 1 1 1 0 Fusaric acid resistance protein family DUF1706 PF08020.11 CBK21453.2 - 1.7 8.5 9.0 3.2 7.6 1.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1706) bZIP_2 PF07716.15 CBK21453.2 - 1.9 8.6 16.7 1.2 9.3 3.8 2.9 2 1 0 2 2 2 0 Basic region leucine zipper DUF4407 PF14362.6 CBK21453.2 - 2.2 7.6 13.1 2.6 7.3 13.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) MRP-S26 PF14943.6 CBK21453.2 - 2.4 8.1 20.7 3 7.7 4.1 2.1 2 0 0 2 2 2 0 Mitochondrial ribosome subunit S26 DUF4140 PF13600.6 CBK21453.2 - 2.8 8.4 11.8 1.9 9.0 4.4 2.2 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) Ank_2 PF12796.7 CBK21454.2 - 3.3e-37 126.9 19.2 7.2e-11 42.5 0.2 7.3 2 2 4 7 7 7 5 Ankyrin repeats (3 copies) Ank_5 PF13857.6 CBK21454.2 - 4.9e-28 96.8 20.6 3.7e-05 23.9 0.3 10.4 6 3 5 11 11 11 8 Ankyrin repeats (many copies) Ank_3 PF13606.6 CBK21454.2 - 5.7e-27 90.8 13.6 0.0014 18.9 0.0 12.4 12 0 0 12 12 12 5 Ankyrin repeat Ank_4 PF13637.6 CBK21454.2 - 1e-25 89.8 21.0 9.1e-06 26.1 0.0 11.6 9 4 3 12 12 12 5 Ankyrin repeats (many copies) Ank PF00023.30 CBK21454.2 - 5.8e-18 64.5 21.4 0.0091 16.4 0.1 10.9 13 0 0 13 13 13 6 Ankyrin repeat DUF249 PF03158.13 CBK21454.2 - 0.069 12.9 4.4 0.12 12.1 0.1 3.1 4 0 0 4 4 4 0 Multigene family 530 protein gp32 PF08804.10 CBK21454.2 - 0.17 11.9 1.7 0.24 11.4 0.6 1.8 2 0 0 2 2 2 0 gp32 DNA binding protein like Glycos_transf_2 PF00535.26 CBK21455.2 - 6.4e-07 29.3 0.0 1.8e-06 27.9 0.0 1.7 2 0 0 2 2 2 1 Glycosyl transferase family 2 Proton_antipo_C PF01010.19 CBK21455.2 - 0.0011 18.6 0.0 0.0021 17.8 0.0 1.3 1 0 0 1 1 1 1 NADH-dehyrogenase subunit F, TMs, (complex I) C-terminus Glyco_tranf_2_3 PF13641.6 CBK21455.2 - 0.0097 15.8 0.1 0.029 14.3 0.1 1.8 2 1 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_transf_7C PF02709.14 CBK21455.2 - 0.31 10.7 3.0 0.22 11.2 0.5 2.0 1 1 1 2 2 2 0 N-terminal domain of galactosyltransferase Hexapep PF00132.24 CBK21456.2 - 1.6e-13 49.7 10.2 1e-05 25.1 0.1 4.2 3 1 1 4 4 4 4 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 CBK21456.2 - 0.036 13.8 8.0 19 5.1 5.6 3.7 2 1 0 2 2 2 0 Hexapeptide repeat of succinyl-transferase Fucokinase PF07959.12 CBK21456.2 - 0.11 11.4 0.4 0.22 10.4 0.3 1.3 1 1 0 1 1 1 0 L-fucokinase DEAD PF00270.29 CBK21457.2 - 7.2e-28 97.5 0.1 1.2e-27 96.8 0.1 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CBK21457.2 - 2.2e-17 63.4 0.0 8.7e-17 61.5 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 CBK21457.2 - 2.4e-09 37.4 0.0 3.8e-09 36.8 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 CBK21457.2 - 0.0022 18.3 0.0 0.0056 17.0 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 CBK21457.2 - 0.0034 17.1 0.0 0.0076 16.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 CBK21457.2 - 0.031 14.6 0.0 0.082 13.2 0.0 1.7 2 0 0 2 2 2 0 AAA domain SWI2_SNF2 PF18766.1 CBK21457.2 - 0.035 13.8 0.0 0.052 13.2 0.0 1.2 1 0 0 1 1 1 0 SWI2/SNF2 ATPase DUF2075 PF09848.9 CBK21457.2 - 0.062 12.5 0.0 0.077 12.2 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Aminotran_1_2 PF00155.21 CBK21458.2 - 5.9e-09 35.6 0.0 1e-08 34.8 0.0 1.3 1 1 0 1 1 1 1 Aminotransferase class I and II Ank_2 PF12796.7 CBK21459.2 - 1.2e-23 83.5 1.1 5.5e-12 46.1 0.6 3.4 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CBK21459.2 - 2.7e-19 69.3 6.2 2.1e-07 31.3 0.1 4.9 1 1 4 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 CBK21459.2 - 1.2e-18 65.2 4.3 0.0018 18.6 0.2 5.6 5 0 0 5 5 5 5 Ankyrin repeat Ank_5 PF13857.6 CBK21459.2 - 4.3e-18 65.1 0.6 1.7e-08 34.6 0.2 4.1 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 CBK21459.2 - 1.2e-13 50.8 15.7 0.017 15.6 0.4 6.0 5 1 1 6 6 6 5 Ankyrin repeat TPR_1 PF00515.28 CBK21459.2 - 6.4e-12 44.8 0.0 0.00057 19.6 0.0 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 CBK21459.2 - 3.5e-11 42.3 0.0 0.0011 18.9 0.0 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.6 CBK21459.2 - 7.1e-09 35.2 0.0 0.0004 20.4 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.6 CBK21459.2 - 2e-06 27.8 0.0 0.00084 19.6 0.0 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.6 CBK21459.2 - 1.8e-05 25.1 0.0 5.5e-05 23.6 0.0 1.8 2 0 0 2 2 1 1 Tetratricopeptide repeat TPR_14 PF13428.6 CBK21459.2 - 0.00023 21.7 0.0 11 7.1 0.0 4.1 4 1 1 5 5 3 0 Tetratricopeptide repeat NYD-SP12_N PF15015.6 CBK21459.2 - 0.00025 19.5 0.2 0.00087 17.8 0.0 1.7 1 1 1 2 2 2 1 Spermatogenesis-associated, N-terminal TPR_11 PF13414.6 CBK21459.2 - 0.00047 19.8 0.0 2.1 8.1 0.0 3.1 1 1 2 3 3 3 2 TPR repeat TPR_16 PF13432.6 CBK21459.2 - 0.0013 19.3 0.0 0.58 10.8 0.0 2.5 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_6 PF13174.6 CBK21459.2 - 0.005 17.4 0.2 0.63 10.8 0.0 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_20 PF14561.6 CBK21459.2 - 0.02 15.2 0.0 0.085 13.2 0.0 2.0 2 0 0 2 2 1 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 CBK21459.2 - 0.031 14.3 0.2 0.15 12.1 0.0 2.2 2 0 0 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat TPR_12 PF13424.6 CBK21459.2 - 0.044 14.1 0.0 0.54 10.6 0.0 2.3 1 1 1 2 2 2 0 Tetratricopeptide repeat Fe-S_biosyn PF01521.20 CBK21460.2 - 4.8e-20 71.8 0.0 6.4e-20 71.4 0.0 1.1 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis DUF3853 PF12964.7 CBK21460.2 - 0.029 14.5 0.0 0.055 13.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3853) Pkinase PF00069.25 CBK21462.2 - 1.7e-36 126.0 0.0 1.7e-36 126.0 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBK21462.2 - 2e-19 69.9 0.0 2e-19 69.9 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.23 CBK21462.2 - 7.3e-05 22.8 0.4 0.0056 16.6 0.0 2.6 2 1 1 3 3 3 2 Phosphotransferase enzyme family Kinase-like PF14531.6 CBK21462.2 - 0.0017 17.7 0.0 0.0034 16.8 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.11 CBK21462.2 - 0.0073 15.4 0.0 0.011 14.8 0.0 1.2 1 0 0 1 1 1 1 Seadornavirus VP7 DUSP PF06337.12 CBK21463.2 - 6.4e-11 42.7 0.0 1.2e-10 41.8 0.0 1.4 1 0 0 1 1 1 1 DUSP domain zf-MYND PF01753.18 CBK21463.2 - 2.4e-09 37.1 9.1 5.3e-09 36.0 9.1 1.6 1 0 0 1 1 1 1 MYND finger UCH PF00443.29 CBK21463.2 - 1.1e-08 35.0 0.0 1.6e-08 34.4 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-HIT PF04438.16 CBK21463.2 - 0.0068 16.3 7.3 0.0068 16.3 7.3 3.0 4 0 0 4 4 4 1 HIT zinc finger UCH PF00443.29 CBK21464.2 - 3e-24 85.9 0.0 3.4e-24 85.7 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 CBK21464.2 - 3.7e-11 43.2 0.0 5.3e-11 42.7 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase NADH_u_ox_C PF12853.7 CBK21464.2 - 0.15 12.1 0.0 0.29 11.1 0.0 1.4 1 0 0 1 1 1 0 C-terminal of NADH-ubiquinone oxidoreductase 21 kDa subunit Metallophos PF00149.28 CBK21465.2 - 5.4e-37 128.3 0.1 7.3e-37 127.8 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 CBK21465.2 - 6.2e-16 58.6 0.2 1.9e-15 57.0 0.1 1.9 2 0 0 2 2 2 1 Serine-threonine protein phosphatase N-terminal domain tRNA-synt_His PF13393.6 CBK21466.2 - 1.5e-42 145.9 0.0 1.5e-42 145.9 0.0 2.4 2 1 0 2 2 2 1 Histidyl-tRNA synthetase HGTP_anticodon PF03129.20 CBK21466.2 - 2.1e-17 63.0 0.2 6.2e-17 61.5 0.2 1.9 1 0 0 1 1 1 1 Anticodon binding domain HGTP_anticodon2 PF12745.7 CBK21466.2 - 1.3e-10 41.3 0.0 1.3e-10 41.3 0.0 1.7 2 0 0 2 2 2 1 Anticodon binding domain of tRNAs tRNA-synt_2 PF00152.20 CBK21466.2 - 7.7e-05 21.9 0.0 0.00026 20.2 0.0 1.8 2 0 0 2 2 2 1 tRNA synthetases class II (D, K and N) TRAM_LAG1_CLN8 PF03798.16 CBK21467.2 - 2.8e-24 86.0 22.0 2.8e-24 86.0 22.0 1.6 2 0 0 2 2 2 1 TLC domain TMEM208_SND2 PF05620.11 CBK21467.2 - 0.0063 16.3 5.9 0.045 13.5 0.0 3.0 3 0 0 3 3 3 2 SRP-independent targeting protein 2/TMEM208 FAM176 PF14851.6 CBK21467.2 - 0.028 14.1 0.3 0.028 14.1 0.3 1.8 2 0 0 2 2 2 0 FAM176 family DUF4834 PF16118.5 CBK21467.2 - 0.16 12.9 0.1 0.16 12.9 0.1 2.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4834) Nrap_D5 PF17406.2 CBK21467.2 - 0.29 10.9 3.1 0.18 11.6 1.1 1.6 2 0 0 2 2 2 0 Nrap protein PAP/OAS1-like domain 5 DUF4611 PF15387.6 CBK21467.2 - 0.77 10.0 8.8 1.1 9.5 8.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) ChW PF07538.11 CBK21468.2 - 3.6e-42 142.0 16.1 2.3e-14 53.0 0.2 6.1 6 0 0 6 6 6 6 Clostridial hydrophobic W FGF PF00167.18 CBK21468.2 - 0.15 12.2 0.0 4.2 7.5 0.0 2.3 2 0 0 2 2 2 0 Fibroblast growth factor Methyltr_RsmB-F PF01189.17 CBK21470.2 - 3.5e-71 239.0 1.5 5.8e-71 238.3 0.0 2.1 2 0 0 2 2 2 1 16S rRNA methyltransferase RsmB/F Methyltr_RsmF_N PF17125.5 CBK21470.2 - 5e-07 30.1 0.4 1.7e-06 28.4 0.0 2.2 2 0 0 2 2 2 1 N-terminal domain of 16S rRNA methyltransferase RsmF FtsJ PF01728.19 CBK21470.2 - 0.00039 20.6 0.1 0.001 19.2 0.1 1.7 1 0 0 1 1 1 1 FtsJ-like methyltransferase Collagen PF01391.18 CBK21470.2 - 0.02 14.6 9.5 0.048 13.4 9.5 1.5 1 0 0 1 1 1 0 Collagen triple helix repeat (20 copies) Adap_comp_sub PF00928.21 CBK21471.2 - 3.3e-84 282.4 0.0 4.1e-84 282.1 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 CBK21471.2 - 0.00015 21.7 4.0 0.00022 21.1 3.6 1.5 1 1 0 1 1 1 1 Clathrin adaptor complex small chain SNF2_N PF00176.23 CBK21472.2 - 1.4e-55 188.4 0.3 2.8e-55 187.5 0.3 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 CBK21472.2 - 5.4e-21 75.0 0.1 2.2e-20 73.1 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Chromo PF00385.24 CBK21472.2 - 6.8e-12 45.1 1.0 1.8e-11 43.8 1.0 1.8 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain ResIII PF04851.15 CBK21472.2 - 7.4e-07 29.3 0.3 5.2e-06 26.6 0.0 2.6 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 CBK21472.2 - 3.5e-06 26.4 0.0 1.5e-05 24.3 0.0 2.0 2 0 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 DEAD PF00270.29 CBK21472.2 - 0.00015 21.6 0.1 0.00085 19.1 0.1 2.1 1 1 0 1 1 1 1 DEAD/DEAH box helicase Pterin_4a PF01329.19 CBK21472.2 - 0.073 13.2 0.1 0.29 11.3 0.1 2.1 1 0 0 1 1 1 0 Pterin 4 alpha carbinolamine dehydratase DUF1949 PF09186.11 CBK21474.2 - 0.0055 16.6 0.0 0.0071 16.2 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1949) DNA_pol_B_2 PF03175.13 CBK21475.2 - 3e-15 56.1 14.7 1.5e-12 47.2 8.7 2.3 2 0 0 2 2 2 2 DNA polymerase type B, organellar and viral ABC_tran PF00005.27 CBK21476.2 - 3.5e-18 66.4 0.0 6.2e-18 65.6 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 CBK21476.2 - 2.2e-08 34.3 0.1 2.8e-08 34.0 0.1 1.2 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 CBK21476.2 - 0.00069 19.1 0.0 0.0009 18.7 0.0 1.2 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain SbcCD_C PF13558.6 CBK21476.2 - 0.083 13.1 0.1 0.96 9.7 0.1 2.2 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit IP_trans PF02121.18 CBK21479.2 - 3.1e-55 187.4 0.1 3.6e-55 187.2 0.1 1.0 1 0 0 1 1 1 1 Phosphatidylinositol transfer protein CK2S PF15011.6 CBK21481.2 - 0.0023 17.8 10.3 0.07 13.0 3.6 2.3 1 1 1 2 2 2 2 Casein Kinase 2 substrate IFT57 PF10498.9 CBK21481.2 - 0.0061 15.6 6.4 0.0061 15.6 6.4 2.3 2 0 0 2 2 2 1 Intra-flagellar transport protein 57 MscS_porin PF12795.7 CBK21481.2 - 0.01 15.4 14.2 0.01 15.4 14.2 1.5 2 0 0 2 2 2 0 Mechanosensitive ion channel porin domain DUF948 PF06103.11 CBK21481.2 - 0.044 14.0 2.6 0.15 12.4 0.8 2.4 1 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) PLAC9 PF15205.6 CBK21481.2 - 0.088 13.2 0.6 0.38 11.2 0.5 2.2 1 1 0 1 1 1 0 Placenta-specific protein 9 PAS_7 PF12860.7 CBK21481.2 - 0.36 11.0 3.0 1 9.5 1.0 2.5 1 1 1 2 2 2 0 PAS fold Exonuc_VII_L PF02601.15 CBK21481.2 - 2.9 7.4 12.2 0.068 12.7 5.5 1.6 2 0 0 2 2 2 0 Exonuclease VII, large subunit DUF966 PF06136.13 CBK21481.2 - 4.3 7.0 11.4 0.54 9.9 2.5 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF966) Atg14 PF10186.9 CBK21481.2 - 7.3 5.6 9.7 15 4.5 9.7 1.5 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Mito_carr PF00153.27 CBK21482.2 - 9.6e-68 224.2 1.4 1.7e-22 79.1 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 CBK21482.2 - 0.019 14.2 0.7 1.9 7.6 0.0 2.7 2 1 0 2 2 2 0 Gammaproteobacterial serine protease AAA_25 PF13481.6 CBK21484.2 - 2.1e-14 53.6 0.0 4.6e-14 52.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain ATPase PF06745.13 CBK21484.2 - 2.5e-13 49.9 0.0 2.6e-09 36.8 0.0 2.2 1 1 1 2 2 2 2 KaiC Rubredoxin_2 PF18073.1 CBK21484.2 - 3.2e-10 39.5 10.4 5.8e-10 38.7 10.4 1.4 1 0 0 1 1 1 1 Rubredoxin metal binding domain ChlI PF13541.6 CBK21484.2 - 1.1e-09 38.2 0.0 2e-09 37.3 0.0 1.5 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase DnaB_C PF03796.15 CBK21484.2 - 1.8e-08 34.1 0.0 4.7e-06 26.1 0.0 2.3 1 1 1 2 2 2 1 DnaB-like helicase C terminal domain AAA_16 PF13191.6 CBK21484.2 - 4.3e-05 24.0 0.0 8.7e-05 23.0 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain Rad51 PF08423.11 CBK21484.2 - 0.00011 21.6 0.1 0.0012 18.1 0.1 2.2 1 1 0 1 1 1 1 Rad51 AAA_14 PF13173.6 CBK21484.2 - 0.00034 20.6 0.0 0.00075 19.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 CBK21484.2 - 0.00059 20.1 0.0 0.0014 18.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 CBK21484.2 - 0.0012 18.6 0.0 0.0057 16.4 0.0 2.0 1 1 0 1 1 1 1 AAA domain Lon_C PF05362.13 CBK21484.2 - 0.0019 17.8 0.0 0.0037 16.8 0.0 1.4 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain GvpD PF07088.11 CBK21484.2 - 0.0061 15.2 0.0 0.13 10.9 0.0 2.1 1 1 0 1 1 1 1 GvpD gas vesicle protein NACHT PF05729.12 CBK21484.2 - 0.012 15.6 0.0 0.019 14.9 0.0 1.4 1 0 0 1 1 1 0 NACHT domain NTPase_1 PF03266.15 CBK21484.2 - 0.027 14.4 0.0 0.23 11.4 0.0 2.2 2 0 0 2 2 2 0 NTPase AAA_5 PF07728.14 CBK21484.2 - 0.04 13.9 0.0 0.09 12.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) DUF2075 PF09848.9 CBK21484.2 - 0.05 12.8 0.0 0.077 12.2 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) ABC_tran PF00005.27 CBK21484.2 - 0.054 14.0 0.0 0.09 13.3 0.0 1.4 1 0 0 1 1 1 0 ABC transporter RNA_helicase PF00910.22 CBK21484.2 - 0.068 13.6 0.0 0.14 12.6 0.0 1.5 1 0 0 1 1 1 0 RNA helicase Zn-ribbon_8 PF09723.10 CBK21484.2 - 0.082 13.0 0.9 0.2 11.8 0.9 1.6 1 0 0 1 1 1 0 Zinc ribbon domain IstB_IS21 PF01695.17 CBK21484.2 - 0.11 12.3 0.0 0.18 11.5 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein DUF2129 PF09902.9 CBK21489.2 - 0.14 12.2 1.6 0.17 12.0 1.4 1.3 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2129) Glyco_transf_49 PF13896.6 CBK21490.2 - 4e-09 36.3 2.6 1.4e-08 34.5 0.3 2.4 2 1 0 2 2 2 1 Glycosyl-transferase for dystroglycan FBA_1 PF07734.13 CBK21490.2 - 0.00089 19.2 1.0 0.0028 17.6 0.6 1.9 1 1 1 2 2 2 2 F-box associated Anth_Ig PF05587.13 CBK21492.2 - 0.045 14.1 1.2 0.12 12.7 0.2 2.0 2 0 0 2 2 2 0 Anthrax receptor extracellular domain Toxin_25 PF08095.11 CBK21493.2 - 0.34 10.9 1.7 0.93 9.5 1.7 1.7 1 0 0 1 1 1 0 Hefutoxin family Pkinase PF00069.25 CBK21494.2 - 7.8e-26 91.0 0.0 9.2e-26 90.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBK21494.2 - 2.3e-14 53.3 0.0 2.8e-14 53.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CBK21494.2 - 2.4e-07 29.9 0.0 2.9e-07 29.6 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 CBK21494.2 - 0.0011 18.9 0.1 0.003 17.5 0.1 1.7 2 0 0 2 2 2 1 Phosphotransferase enzyme family Peptidase_M41 PF01434.18 CBK21495.2 - 3.5e-45 154.2 0.0 6.7e-45 153.3 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 CBK21495.2 - 7.4e-41 139.7 0.0 1.5e-40 138.7 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CBK21495.2 - 5.9e-09 35.6 0.0 1.2e-08 34.6 0.0 1.5 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 CBK21495.2 - 7e-06 26.5 0.3 0.00043 20.7 0.1 2.6 2 1 1 3 3 3 1 AAA ATPase domain AAA_5 PF07728.14 CBK21495.2 - 4.3e-05 23.5 0.0 0.00016 21.7 0.0 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 CBK21495.2 - 0.00012 22.4 0.1 0.016 15.5 0.0 3.1 3 0 0 3 3 3 1 AAA domain TIP49 PF06068.13 CBK21495.2 - 0.00016 21.0 0.0 0.00027 20.3 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain RuvB_N PF05496.12 CBK21495.2 - 0.00071 19.4 0.0 0.0018 18.0 0.0 1.7 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain IstB_IS21 PF01695.17 CBK21495.2 - 0.001 18.9 0.1 0.0028 17.4 0.0 1.8 2 0 0 2 2 2 1 IstB-like ATP binding protein PhoH PF02562.16 CBK21495.2 - 0.0012 18.3 0.9 0.14 11.6 0.1 2.3 2 0 0 2 2 2 1 PhoH-like protein AAA_18 PF13238.6 CBK21495.2 - 0.0014 19.2 0.0 0.0058 17.2 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_2 PF07724.14 CBK21495.2 - 0.0023 18.0 0.0 0.0068 16.5 0.0 1.9 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) DUF2075 PF09848.9 CBK21495.2 - 0.011 15.1 0.0 0.28 10.4 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) Mg_chelatase PF01078.21 CBK21495.2 - 0.012 15.0 0.2 0.025 14.0 0.2 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.26 CBK21495.2 - 0.018 14.8 0.0 0.067 12.9 0.0 1.9 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_14 PF13173.6 CBK21495.2 - 0.03 14.3 0.0 0.062 13.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 CBK21495.2 - 0.031 14.8 0.4 0.19 12.2 0.1 2.2 2 0 0 2 2 2 0 ABC transporter ATPase PF06745.13 CBK21495.2 - 0.032 13.6 0.1 0.078 12.3 0.1 1.6 2 0 0 2 2 2 0 KaiC AAA_28 PF13521.6 CBK21495.2 - 0.039 14.2 0.0 0.076 13.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 CBK21495.2 - 0.049 13.8 0.0 0.093 12.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 CBK21495.2 - 0.05 13.1 0.1 0.21 11.1 0.1 2.0 1 1 0 1 1 1 0 P-loop containing dynein motor region Peptidase_M50B PF13398.6 CBK21495.2 - 0.072 12.7 0.0 0.11 12.1 0.0 1.2 1 0 0 1 1 1 0 Peptidase M50B-like NACHT PF05729.12 CBK21495.2 - 0.097 12.6 0.0 0.25 11.3 0.0 1.7 1 0 0 1 1 1 0 NACHT domain Parvo_NS1 PF01057.17 CBK21495.2 - 0.13 11.3 0.0 0.24 10.5 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Sigma54_activ_2 PF14532.6 CBK21495.2 - 0.14 12.3 0.0 0.32 11.1 0.0 1.7 1 0 0 1 1 1 0 Sigma-54 interaction domain Zeta_toxin PF06414.12 CBK21495.2 - 0.14 11.4 0.5 0.39 10.0 0.5 1.7 1 0 0 1 1 1 0 Zeta toxin AAA_25 PF13481.6 CBK21495.2 - 0.17 11.5 0.2 0.66 9.5 0.2 1.8 1 1 1 2 2 2 0 AAA domain AAA_19 PF13245.6 CBK21495.2 - 0.27 11.6 2.5 0.99 9.7 0.4 2.6 3 0 0 3 3 2 0 AAA domain EF1_GNE PF00736.19 CBK21496.2 - 3e-25 88.2 0.3 3e-25 88.2 0.3 1.9 2 0 0 2 2 1 1 EF-1 guanine nucleotide exchange domain Sigma70_ner PF04546.13 CBK21496.2 - 3e-05 24.0 5.8 5.2e-05 23.2 5.8 1.4 1 0 0 1 1 1 1 Sigma-70, non-essential region EF-1_beta_acid PF10587.9 CBK21496.2 - 0.00013 22.3 12.6 0.00013 22.3 12.6 3.2 3 0 0 3 3 2 1 Eukaryotic elongation factor 1 beta central acidic region Cnd2 PF05786.14 CBK21496.2 - 0.0027 16.5 12.0 0.0038 16.0 12.0 1.1 1 0 0 1 1 1 1 Condensin complex subunit 2 DUF2052 PF09747.9 CBK21496.2 - 0.0094 16.1 5.9 0.014 15.6 5.9 1.2 1 0 0 1 1 1 1 Coiled-coil domain containing protein (DUF2052) PBP1_TM PF14812.6 CBK21496.2 - 0.038 14.4 3.1 0.077 13.4 3.1 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal FAM176 PF14851.6 CBK21496.2 - 0.073 12.7 3.0 0.14 11.8 3.0 1.4 1 0 0 1 1 1 0 FAM176 family GOLD_2 PF13897.6 CBK21496.2 - 0.08 13.4 4.8 0.19 12.3 4.8 1.7 1 1 0 1 1 1 0 Golgi-dynamics membrane-trafficking SPT6_acidic PF14632.6 CBK21496.2 - 0.21 12.2 15.5 0.44 11.2 15.5 1.5 1 0 0 1 1 1 0 Acidic N-terminal SPT6 DUF2868 PF11067.8 CBK21496.2 - 0.24 10.9 0.2 0.3 10.6 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2868) Pox_Ag35 PF03286.14 CBK21496.2 - 0.24 11.2 12.6 0.42 10.4 12.6 1.3 1 0 0 1 1 1 0 Pox virus Ag35 surface protein TRAP_alpha PF03896.16 CBK21496.2 - 0.57 9.3 5.0 0.94 8.6 5.0 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit CDC45 PF02724.14 CBK21496.2 - 0.63 8.3 6.1 0.82 7.9 6.1 1.1 1 0 0 1 1 1 0 CDC45-like protein PTPRCAP PF15713.5 CBK21496.2 - 0.75 10.1 10.2 1.1 9.5 10.2 1.2 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated HBS1_N PF08938.10 CBK21496.2 - 0.91 9.9 10.2 3.1 8.2 0.1 2.4 2 0 0 2 2 2 0 HBS1 N-terminus DUF5383 PF17355.2 CBK21496.2 - 2.3 8.6 7.3 4 7.8 7.3 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5383) Cwf_Cwc_15 PF04889.12 CBK21496.2 - 2.7 7.7 15.4 5.3 6.7 15.4 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein CENP-B_dimeris PF09026.10 CBK21496.2 - 5.5 7.4 10.7 17 5.9 10.4 1.9 2 0 0 2 2 2 0 Centromere protein B dimerisation domain DNA_pol_phi PF04931.13 CBK21496.2 - 7.9 4.4 14.5 11 4.0 14.5 1.1 1 0 0 1 1 1 0 DNA polymerase phi Pkinase PF00069.25 CBK21498.2 - 2.3e-52 178.0 0.0 2.8e-52 177.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBK21498.2 - 3.4e-44 151.1 0.0 4.3e-44 150.7 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 CBK21498.2 - 0.0002 20.4 0.0 0.0011 18.0 0.0 1.9 2 0 0 2 2 2 1 Haspin like kinase domain RIO1 PF01163.22 CBK21498.2 - 0.00078 19.1 0.0 0.21 11.2 0.0 2.4 3 0 0 3 3 3 2 RIO1 family APH PF01636.23 CBK21498.2 - 0.0025 17.8 0.0 0.0053 16.7 0.0 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 CBK21498.2 - 0.0064 15.3 0.0 0.0092 14.8 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 CBK21498.2 - 0.011 15.2 0.0 0.017 14.5 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF1125 PF06563.11 CBK21498.2 - 0.027 14.4 0.2 0.048 13.6 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1125) FTA2 PF13095.6 CBK21498.2 - 0.038 13.6 0.0 5.3 6.6 0.0 2.2 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Pox_ser-thr_kin PF05445.11 CBK21498.2 - 0.082 11.9 0.0 0.12 11.3 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Dynein_light PF01221.18 CBK21499.2 - 7.2e-28 96.7 0.2 7.9e-28 96.6 0.2 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 Peptidase_C1 PF00112.23 CBK21500.2 - 6.9e-13 49.2 0.0 1.1e-12 48.5 0.0 1.2 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 CBK21500.2 - 0.089 13.2 0.0 0.15 12.5 0.0 1.3 1 0 0 1 1 1 0 Cathepsin propeptide inhibitor domain (I29) V-SNARE_C PF12352.8 CBK21501.2 - 1.6e-05 25.1 3.2 4.9e-05 23.5 2.9 1.8 1 1 1 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.13 CBK21501.2 - 3e-05 23.9 0.8 4e-05 23.4 0.8 1.3 1 0 0 1 1 1 1 Sec20 Chordopox_A13L PF05961.11 CBK21501.2 - 0.011 16.0 0.2 0.019 15.2 0.2 1.5 1 0 0 1 1 1 0 Chordopoxvirus A13L protein Orf78 PF06024.12 CBK21501.2 - 0.013 15.8 0.1 0.018 15.3 0.1 1.3 1 0 0 1 1 1 0 Orf78 (ac78) GP41 PF00517.17 CBK21501.2 - 0.044 13.7 0.1 0.05 13.5 0.1 1.1 1 0 0 1 1 1 0 Retroviral envelope protein Amnionless PF14828.6 CBK21501.2 - 0.22 10.3 0.2 0.23 10.3 0.2 1.0 1 0 0 1 1 1 0 Amnionless Synaptobrevin PF00957.21 CBK21501.2 - 0.5 10.2 5.2 1.1 9.1 5.2 1.6 1 1 0 1 1 1 0 Synaptobrevin DUF948 PF06103.11 CBK21501.2 - 8.4 6.7 8.6 0.64 10.3 1.7 2.1 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Pkinase PF00069.25 CBK21502.2 - 1.7e-36 126.0 0.0 1.7e-36 126.0 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBK21502.2 - 1.9e-19 69.9 0.0 1.9e-19 69.9 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.23 CBK21502.2 - 7.1e-05 22.8 0.4 0.0055 16.6 0.0 2.6 2 1 1 3 3 3 2 Phosphotransferase enzyme family Kinase-like PF14531.6 CBK21502.2 - 0.0017 17.7 0.0 0.0033 16.8 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.11 CBK21502.2 - 0.0073 15.4 0.0 0.011 14.8 0.0 1.2 1 0 0 1 1 1 1 Seadornavirus VP7 RRM_1 PF00076.22 CBK21504.2 - 5.3e-41 138.3 0.2 2.7e-19 68.7 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 CBK21504.2 - 1.3e-05 25.1 0.0 5.4e-05 23.1 0.0 2.1 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif RRM_7 PF16367.5 CBK21504.2 - 0.00013 22.0 0.0 0.27 11.4 0.0 3.1 2 0 0 2 2 2 2 RNA recognition motif Nup35_RRM PF05172.13 CBK21504.2 - 0.0018 18.2 0.0 0.02 14.8 0.0 2.3 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif RRM_5 PF13893.6 CBK21504.2 - 0.0032 17.0 0.0 0.006 16.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 CBK21504.2 - 0.0084 16.0 0.0 0.33 10.8 0.0 2.4 2 0 0 2 2 2 1 Occluded RNA-recognition motif Limkain-b1 PF11608.8 CBK21504.2 - 0.029 14.4 0.5 0.26 11.4 0.1 2.5 2 0 0 2 2 2 0 Limkain b1 PHD PF00628.29 CBK21505.2 - 5.9e-07 29.3 4.9 7.8e-07 28.9 4.9 1.2 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.6 CBK21505.2 - 0.0011 19.2 1.8 0.0011 19.2 1.8 1.4 1 1 0 1 1 1 1 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.6 CBK21505.2 - 0.022 14.9 1.6 0.022 14.9 1.6 1.3 1 1 0 1 1 1 0 PHD-zinc-finger like domain Sec8_exocyst PF04048.14 CBK21506.2 - 3.4e-11 43.2 0.3 5.4e-11 42.5 0.3 1.4 1 0 0 1 1 1 1 Sec8 exocyst complex component specific domain Vps54_N PF10475.9 CBK21506.2 - 9.1e-07 28.4 3.4 1.1e-06 28.2 3.4 1.1 1 0 0 1 1 1 1 Vacuolar-sorting protein 54, of GARP complex COG2 PF06148.11 CBK21506.2 - 0.00059 19.9 0.9 0.001 19.2 0.9 1.4 1 0 0 1 1 1 1 COG (conserved oligomeric Golgi) complex component, COG2 HMW1C_N PF18071.1 CBK21506.2 - 0.053 13.3 0.0 0.13 12.1 0.0 1.7 1 0 0 1 1 1 0 HMW1C N-terminal DEAD PF00270.29 CBK21507.2 - 4.2e-43 147.1 0.0 2.7e-42 144.5 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CBK21507.2 - 2e-33 115.0 0.0 7e-32 110.1 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ERCC3_RAD25_C PF16203.5 CBK21507.2 - 0.006 15.8 0.0 0.0091 15.2 0.0 1.2 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase CMS1 PF14617.6 CBK21507.2 - 0.038 13.3 0.1 0.07 12.5 0.1 1.3 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit UTP25 PF06862.12 CBK21507.2 - 0.058 12.2 0.0 0.19 10.5 0.0 1.8 3 0 0 3 3 3 0 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 Foamy_BEL PF03274.14 CBK21507.2 - 0.071 12.4 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 Foamy virus BEL 1/2 protein ResIII PF04851.15 CBK21507.2 - 0.13 12.3 0.0 0.28 11.2 0.0 1.6 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit PP2C PF00481.21 CBK21508.2 - 3.4e-68 230.1 0.0 4.2e-68 229.8 0.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 CBK21508.2 - 3.8e-07 30.0 0.0 8.5e-07 28.8 0.0 1.6 1 1 0 1 1 1 1 Protein phosphatase 2C PP2C_C PF07830.13 CBK21508.2 - 0.33 11.5 2.1 0.61 10.6 2.1 1.5 1 0 0 1 1 1 0 Protein serine/threonine phosphatase 2C, C-terminal domain SPRY PF00622.28 CBK21510.2 - 9.3e-10 38.7 0.0 1.1e-06 28.7 0.0 2.3 2 0 0 2 2 2 2 SPRY domain HECT PF00632.25 CBK21511.2 - 2.7e-39 135.5 0.0 3.6e-36 125.2 0.0 2.6 2 1 1 3 3 3 2 HECT-domain (ubiquitin-transferase) SPRY PF00622.28 CBK21511.2 - 9.3e-09 35.4 0.2 2.4e-08 34.1 0.2 1.7 1 0 0 1 1 1 1 SPRY domain TPR_2 PF07719.17 CBK21512.2 - 1.7e-15 55.8 1.5 0.00034 20.5 0.1 3.8 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_1 PF00515.28 CBK21512.2 - 3.4e-11 42.5 3.9 2.9e-05 23.7 0.4 3.9 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_11 PF13414.6 CBK21512.2 - 7.1e-08 32.0 0.1 0.00029 20.5 0.0 3.5 3 0 0 3 3 3 1 TPR repeat TPR_12 PF13424.6 CBK21512.2 - 7.2e-08 32.6 0.3 0.0067 16.7 0.0 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 CBK21512.2 - 1.5e-06 28.5 0.0 0.23 12.4 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 CBK21512.2 - 9.6e-06 26.0 0.3 0.062 13.8 0.3 2.6 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 CBK21512.2 - 2.9e-05 23.9 1.8 2 8.8 0.0 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 CBK21512.2 - 8.1e-05 22.4 0.2 0.53 10.4 0.1 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 CBK21512.2 - 0.00015 22.3 0.2 1.9 9.2 0.0 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat Thioredoxin PF00085.20 CBK21512.2 - 0.0018 18.3 0.0 0.0043 17.0 0.0 1.7 1 0 0 1 1 1 1 Thioredoxin TPR_10 PF13374.6 CBK21512.2 - 0.0041 16.9 1.4 0.83 9.6 1.4 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.6 CBK21512.2 - 0.0086 16.2 0.5 0.64 10.2 0.1 2.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.6 CBK21512.2 - 0.013 15.8 5.3 0.48 10.9 0.5 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat ANAPC3 PF12895.7 CBK21512.2 - 0.017 15.3 7.4 0.19 11.9 1.3 2.7 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 SHNi-TPR PF10516.9 CBK21512.2 - 0.036 13.5 0.2 0.29 10.6 0.1 2.2 2 0 0 2 2 2 0 SHNi-TPR Coatomer_E PF04733.14 CBK21512.2 - 0.076 12.4 0.0 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 Coatomer epsilon subunit Thioredoxin_8 PF13905.6 CBK21512.2 - 0.18 12.2 0.4 9 6.7 0.1 2.8 2 1 1 3 3 3 0 Thioredoxin-like TPR_6 PF13174.6 CBK21512.2 - 0.68 10.7 3.5 9.5 7.1 0.2 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat Thioredoxin PF00085.20 CBK21513.2 - 1.3e-09 37.9 0.0 1.4e-09 37.8 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 CBK21513.2 - 0.00023 21.6 0.0 0.00027 21.4 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin-like domain Spc29 PF17082.5 CBK21514.2 - 5.7e-05 23.1 3.9 5.7e-05 23.1 3.9 2.0 1 1 1 2 2 2 1 Spindle Pole Component 29 APG6_N PF17675.1 CBK21514.2 - 0.00076 20.0 32.2 0.0035 17.9 12.5 2.1 1 1 1 2 2 2 2 Apg6 coiled-coil region Filament PF00038.21 CBK21514.2 - 0.001 18.7 23.7 0.0019 17.9 15.8 2.2 1 1 1 2 2 2 1 Intermediate filament protein GAS PF13851.6 CBK21514.2 - 0.0018 17.6 23.4 0.0026 17.1 23.4 1.3 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding AAA_13 PF13166.6 CBK21514.2 - 0.0054 15.4 13.7 0.0069 15.1 13.7 1.1 1 0 0 1 1 1 1 AAA domain DUF3958 PF13125.6 CBK21514.2 - 0.0076 16.4 4.4 0.0076 16.4 4.4 2.7 2 1 0 2 2 2 1 Protein of unknown function (DUF3958) FlxA PF14282.6 CBK21514.2 - 0.026 14.5 19.9 0.026 14.5 18.4 1.8 1 1 1 2 2 2 0 FlxA-like protein ADIP PF11559.8 CBK21514.2 - 0.037 14.1 24.3 0.026 14.6 15.4 2.1 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding CENP-F_leu_zip PF10473.9 CBK21514.2 - 0.048 13.7 26.3 0.067 13.2 9.6 2.3 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Pox_A_type_inc PF04508.12 CBK21514.2 - 0.077 12.9 0.2 0.077 12.9 0.2 3.6 4 0 0 4 4 4 0 Viral A-type inclusion protein repeat YabA PF06156.13 CBK21514.2 - 0.083 13.5 14.2 0.74 10.5 14.2 2.3 1 1 0 1 1 1 0 Initiation control protein YabA DUF1664 PF07889.12 CBK21514.2 - 0.1 12.6 10.7 0.41 10.7 3.1 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DUF4407 PF14362.6 CBK21514.2 - 0.13 11.5 16.5 0.22 10.8 16.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Tektin PF03148.14 CBK21514.2 - 0.16 10.7 23.2 0.25 10.1 14.5 2.0 1 1 1 2 2 2 0 Tektin family Spc7 PF08317.11 CBK21514.2 - 0.19 10.6 27.2 0.57 9.0 27.2 1.7 1 1 0 1 1 1 0 Spc7 kinetochore protein DUF4200 PF13863.6 CBK21514.2 - 0.22 11.9 30.3 0.75 10.2 20.8 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) Atg14 PF10186.9 CBK21514.2 - 0.24 10.4 17.1 0.35 9.9 17.1 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Exonuc_VII_L PF02601.15 CBK21514.2 - 0.26 10.8 9.0 0.36 10.4 9.0 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit Baculo_PEP_C PF04513.12 CBK21514.2 - 0.32 11.0 2.9 0.73 9.9 2.6 1.7 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DDHD PF02862.17 CBK21514.2 - 0.33 11.1 1.8 0.35 11.0 1.8 1.1 1 0 0 1 1 1 0 DDHD domain TPR_MLP1_2 PF07926.12 CBK21514.2 - 0.49 10.5 28.7 2.2 8.4 9.5 2.2 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein PspA_IM30 PF04012.12 CBK21514.2 - 0.51 9.9 26.9 14 5.2 26.8 2.2 1 1 0 1 1 1 0 PspA/IM30 family Golgin_A5 PF09787.9 CBK21514.2 - 0.52 9.7 25.0 4 6.8 24.8 1.8 1 1 0 1 1 1 0 Golgin subfamily A member 5 V_ATPase_I PF01496.19 CBK21514.2 - 0.88 7.4 8.5 1.2 7.0 8.5 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF3584 PF12128.8 CBK21514.2 - 1.1 6.6 23.3 1.4 6.4 23.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Prominin PF05478.11 CBK21514.2 - 1.9 6.4 6.4 2.4 6.0 6.4 1.2 1 0 0 1 1 1 0 Prominin Fez1 PF06818.15 CBK21514.2 - 1.9 8.9 24.4 6.9 7.1 22.5 1.8 1 1 0 1 1 1 0 Fez1 NPV_P10 PF05531.12 CBK21514.2 - 2.2 8.8 8.1 3.6 8.1 5.8 2.4 1 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF948 PF06103.11 CBK21514.2 - 2.4 8.5 7.8 12 6.3 2.8 2.5 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF948) HAUS-augmin3 PF14932.6 CBK21514.2 - 2.5 7.6 19.9 1.4 8.5 9.9 2.0 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 3 BST2 PF16716.5 CBK21514.2 - 3 8.5 19.1 0.64 10.6 10.4 2.6 1 1 1 2 2 2 0 Bone marrow stromal antigen 2 TolA_bind_tri PF16331.5 CBK21514.2 - 3 8.0 15.7 10 6.3 13.0 2.8 1 1 0 2 2 2 0 TolA binding protein trimerisation ALMT PF11744.8 CBK21514.2 - 3.1 6.5 9.1 3.8 6.2 9.1 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter FUSC PF04632.12 CBK21514.2 - 3.2 6.2 7.5 4.5 5.7 7.5 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family CENP-H PF05837.12 CBK21514.2 - 4.1 7.9 22.8 1.6e+02 2.7 22.1 2.2 1 1 0 1 1 1 0 Centromere protein H (CENP-H) DUF2203 PF09969.9 CBK21514.2 - 4.6 8.0 17.1 1.5 9.5 2.7 2.2 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) DUF2205 PF10224.9 CBK21514.2 - 5.8 7.0 23.8 4.3 7.4 3.4 4.4 1 1 3 4 4 4 0 Short coiled-coil protein Jnk-SapK_ap_N PF09744.9 CBK21514.2 - 6.8 6.9 28.9 1.8 8.8 11.5 2.1 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 DUF812 PF05667.11 CBK21514.2 - 8.5 5.1 25.6 14 4.4 25.6 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF812) Med9 PF07544.13 CBK21514.2 - 8.7 6.5 24.0 2.3 8.3 5.0 3.1 1 1 2 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 DUF3450 PF11932.8 CBK21514.2 - 9.2 5.5 21.2 3.6 6.8 10.1 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) Prefoldin_2 PF01920.20 CBK21514.2 - 9.5 6.2 27.5 4.5 7.3 9.6 3.3 1 1 0 2 2 2 0 Prefoldin subunit Fib_alpha PF08702.10 CBK21514.2 - 9.6 6.4 13.2 19 5.4 3.2 2.1 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Spc24 PF08286.11 CBK21514.2 - 9.6 6.5 18.7 5.7 7.2 3.9 2.7 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 zf-CCCH_3 PF15663.5 CBK21515.2 - 2.7e-14 53.3 5.6 1.3e-10 41.5 1.3 2.3 2 0 0 2 2 2 2 Zinc-finger containing family Torus PF16131.5 CBK21515.2 - 2.9e-10 40.8 12.6 5.4e-07 30.3 0.3 3.8 3 1 1 4 4 4 2 Torus domain zf-CCCH_2 PF14608.6 CBK21515.2 - 4.5e-07 30.1 24.6 0.00072 19.9 1.2 3.5 3 0 0 3 3 3 3 RNA-binding, Nab2-type zinc finger zf_CCCH_4 PF18345.1 CBK21515.2 - 1.2e-05 25.1 31.4 0.0026 17.8 8.0 4.5 4 1 0 4 4 4 2 Zinc finger domain zf-CCCH_4 PF18044.1 CBK21515.2 - 6.8e-05 22.6 24.1 0.0037 17.0 7.7 3.0 3 0 0 3 3 3 2 CCCH-type zinc finger zf-CCCH PF00642.24 CBK21515.2 - 7.1e-05 22.6 16.9 0.00087 19.1 4.4 3.6 3 0 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-C3H1 PF10650.9 CBK21515.2 - 0.061 13.1 11.0 0.21 11.4 0.2 3.4 3 0 0 3 3 3 0 Putative zinc-finger domain HSP70 PF00012.20 CBK21516.2 - 2.6e-74 250.5 0.0 3.5e-74 250.1 0.0 1.2 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 CBK21516.2 - 1.1e-13 50.7 0.0 1.1e-12 47.5 0.0 2.3 2 1 0 2 2 2 1 MreB/Mbl protein FtsA PF14450.6 CBK21516.2 - 6.5e-06 26.5 0.8 0.031 14.7 0.1 2.8 2 1 0 2 2 2 2 Cell division protein FtsA DDR PF08841.10 CBK21516.2 - 0.011 14.8 0.1 0.97 8.4 0.0 2.7 3 0 0 3 3 3 0 Diol dehydratase reactivase ATPase-like domain Hydantoinase_A PF01968.18 CBK21516.2 - 0.017 14.4 0.3 0.69 9.1 0.0 2.3 2 0 0 2 2 2 0 Hydantoinase/oxoprolinase StbA PF06406.11 CBK21516.2 - 0.052 12.8 0.0 0.13 11.5 0.0 1.7 1 0 0 1 1 1 0 StbA protein BcrAD_BadFG PF01869.20 CBK21516.2 - 0.11 12.0 0.2 0.28 10.7 0.2 1.7 1 0 0 1 1 1 0 BadF/BadG/BcrA/BcrD ATPase family UPF0184 PF03670.13 CBK21516.2 - 0.2 12.1 1.1 0.53 10.7 1.1 1.8 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0184) TRAP_alpha PF03896.16 CBK21517.2 - 1.1e-11 44.5 2.4 1.1e-11 44.5 2.4 1.1 1 0 0 1 1 1 1 Translocon-associated protein (TRAP), alpha subunit Peptidase_C50 PF03568.17 CBK21518.2 - 2.1e-26 93.0 11.5 2.1e-07 30.4 0.8 4.1 3 1 0 4 4 4 4 Peptidase family C50 RAP1 PF07218.11 CBK21518.2 - 3.1 6.0 4.5 4.4 5.5 4.5 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) zf-C2H2_4 PF13894.6 CBK21519.2 - 3e-09 36.9 22.9 0.0001 22.8 0.7 5.6 5 0 0 5 5 5 3 C2H2-type zinc finger zf-C2H2 PF00096.26 CBK21519.2 - 4.7e-08 33.1 25.8 4.9e-05 23.6 1.0 5.7 5 0 0 5 5 5 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 CBK21519.2 - 1.2e-05 25.5 2.0 1.2e-05 25.5 2.0 6.5 7 0 0 7 7 7 2 Zinc-finger double domain zf-C2H2_aberr PF17017.5 CBK21519.2 - 0.0011 19.1 5.8 0.34 11.0 0.1 3.0 2 1 1 3 3 3 2 Aberrant zinc-finger zf-C2H2_6 PF13912.6 CBK21519.2 - 0.0012 18.8 11.7 0.065 13.3 0.5 4.2 4 0 0 4 4 4 2 C2H2-type zinc finger zf-C2H2_8 PF15909.5 CBK21519.2 - 0.0081 16.4 5.0 8.8 6.7 0.1 3.4 3 0 0 3 3 3 1 C2H2-type zinc ribbon DUF2197 PF09963.9 CBK21519.2 - 0.029 14.6 0.1 0.11 12.8 0.1 2.0 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2197) YppF PF14178.6 CBK21519.2 - 0.073 13.0 0.4 0.16 11.8 0.4 1.5 1 0 0 1 1 1 0 YppF-like protein FOXP-CC PF16159.5 CBK21519.2 - 0.12 13.1 0.2 0.12 13.1 0.2 4.2 3 1 1 4 4 4 0 FOXP coiled-coil domain zf-C2H2_11 PF16622.5 CBK21519.2 - 0.23 11.2 5.4 0.69 9.7 0.8 2.5 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-C2H2_jaz PF12171.8 CBK21519.2 - 0.4 11.0 0.1 0.4 11.0 0.1 4.0 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 CBK21519.2 - 0.75 10.3 0.1 0.75 10.3 0.1 4.4 5 0 0 5 5 5 0 Zinc-finger of C2H2 type Glucosamine_iso PF01182.20 CBK21520.2 - 8.5e-05 22.5 0.0 0.21 11.4 0.0 2.2 2 0 0 2 2 2 2 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase Med26 PF08711.11 CBK21521.2 - 7.2e-05 22.7 0.8 0.00016 21.6 0.8 1.5 1 0 0 1 1 1 1 TFIIS helical bundle-like domain DUF3842 PF12953.7 CBK21521.2 - 0.18 12.2 0.0 0.32 11.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3842) HSP70 PF00012.20 CBK21522.2 - 5.1e-148 493.9 11.8 4.2e-116 388.5 0.7 2.8 2 1 0 2 2 2 2 Hsp70 protein MreB_Mbl PF06723.13 CBK21522.2 - 6.7e-14 51.4 0.8 6.2e-12 45.0 0.3 2.6 2 1 0 2 2 2 2 MreB/Mbl protein FtsA PF14450.6 CBK21522.2 - 0.0072 16.7 2.5 0.062 13.7 0.2 3.0 2 2 0 2 2 2 1 Cell division protein FtsA DXP_synthase_N PF13292.6 CBK21522.2 - 0.036 13.3 0.7 0.075 12.2 0.7 1.5 1 0 0 1 1 1 0 1-deoxy-D-xylulose-5-phosphate synthase Hydantoinase_A PF01968.18 CBK21522.2 - 0.096 11.9 0.1 0.36 10.1 0.1 1.9 2 0 0 2 2 2 0 Hydantoinase/oxoprolinase DUF2805 PF10985.8 CBK21522.2 - 0.15 12.5 4.2 0.063 13.7 1.5 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2805) Ribosomal_60s PF00428.19 CBK21523.2 - 1.1e-18 67.6 7.8 1.4e-18 67.2 7.8 1.2 1 0 0 1 1 1 1 60s Acidic ribosomal protein DUF3824 PF12868.7 CBK21523.2 - 0.11 13.2 2.2 0.14 12.8 2.2 1.1 1 0 0 1 1 1 0 Domain of unknwon function (DUF3824) Shadoo PF14999.6 CBK21523.2 - 0.81 9.8 7.8 0.97 9.5 7.1 1.4 1 1 0 1 1 1 0 Shadow of prion protein, neuroprotective SpoIIE PF07228.12 CBK21524.2 - 0.00021 21.3 0.0 0.00069 19.6 0.0 1.8 1 1 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) Ras PF00071.22 CBK21525.2 - 2.6e-52 176.7 1.1 3.7e-52 176.2 1.1 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CBK21525.2 - 3.9e-28 98.1 2.6 4.8e-28 97.8 0.8 2.0 2 1 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CBK21525.2 - 1.6e-12 47.2 0.1 2.2e-12 46.8 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 CBK21525.2 - 6.7e-05 22.8 0.8 0.27 11.1 0.1 2.3 1 1 0 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 CBK21525.2 - 7.7e-05 22.3 0.2 0.0004 20.0 0.0 1.9 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 CBK21525.2 - 0.0014 18.7 0.0 0.003 17.6 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 CBK21525.2 - 0.0032 16.9 0.0 0.0049 16.3 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_24 PF13479.6 CBK21525.2 - 0.03 14.0 0.6 0.28 10.9 0.1 2.2 1 1 0 2 2 2 0 AAA domain AAA_5 PF07728.14 CBK21525.2 - 0.043 13.8 0.0 0.11 12.5 0.0 1.7 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 CBK21525.2 - 0.067 13.5 0.0 1.2 9.5 0.0 2.3 1 1 0 1 1 1 0 AAA domain BRCT PF00533.26 CBK21526.2 - 1.2e-07 32.0 0.2 5.8e-06 26.6 0.0 2.8 3 0 0 3 3 2 1 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 CBK21526.2 - 1.9e-07 31.4 0.6 0.0024 18.3 0.0 2.8 3 0 0 3 3 2 2 BRCT domain, a BRCA1 C-terminus domain RTT107_BRCT_5 PF16770.5 CBK21526.2 - 3.2e-07 30.2 0.0 2.4e-06 27.3 0.0 2.6 3 1 0 3 3 3 1 Regulator of Ty1 transposition protein 107 BRCT domain zf-RanBP PF00641.18 CBK21526.2 - 2.1e-05 23.8 6.5 3.9e-05 22.9 6.5 1.5 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others PTCB-BRCT PF12738.7 CBK21526.2 - 0.00015 21.6 0.0 0.0003 20.7 0.0 1.5 1 0 0 1 1 1 1 twin BRCT domain SDA1 PF05285.12 CBK21526.2 - 0.0034 16.9 18.6 0.0049 16.4 18.6 1.2 1 0 0 1 1 1 1 SDA1 CDC45 PF02724.14 CBK21526.2 - 0.013 13.9 12.1 0.015 13.6 12.1 1.1 1 0 0 1 1 1 0 CDC45-like protein BRCT_3 PF18428.1 CBK21526.2 - 0.016 15.3 0.0 0.046 13.8 0.0 1.8 1 0 0 1 1 1 0 BRCA1 C Terminus (BRCT) domain Nop14 PF04147.12 CBK21526.2 - 0.053 11.8 20.0 0.069 11.4 20.0 1.1 1 0 0 1 1 1 0 Nop14-like family Borrelia_P83 PF05262.11 CBK21526.2 - 0.13 10.8 16.8 0.19 10.2 16.8 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein LicD PF04991.13 CBK21526.2 - 0.25 11.5 5.6 0.47 10.5 5.6 1.4 1 0 0 1 1 1 0 LicD family PTPRCAP PF15713.5 CBK21526.2 - 0.3 11.4 16.0 0.71 10.2 16.0 1.6 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated DUF2052 PF09747.9 CBK21526.2 - 0.41 10.8 17.4 0.81 9.8 17.4 1.5 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) RR_TM4-6 PF06459.12 CBK21526.2 - 0.44 10.3 19.1 0.68 9.7 19.1 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 CCSAP PF15748.5 CBK21526.2 - 0.72 10.0 18.1 1.4 9.0 18.1 1.4 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated Presenilin PF01080.17 CBK21526.2 - 1 8.0 11.4 1.6 7.4 11.4 1.3 1 0 0 1 1 1 0 Presenilin MDM1 PF15501.6 CBK21526.2 - 1.7 7.7 24.9 2.4 7.2 24.9 1.2 1 0 0 1 1 1 0 Nuclear protein MDM1 eIF-3c_N PF05470.12 CBK21526.2 - 2.2 6.5 14.0 3 6.1 14.0 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus RabGAP-TBC PF00566.18 CBK21526.2 - 2.2 7.9 5.6 7.3 6.2 5.6 1.9 2 0 0 2 2 2 0 Rab-GTPase-TBC domain SLC12 PF03522.15 CBK21526.2 - 6.2 5.7 13.8 9.1 5.2 13.8 1.2 1 0 0 1 1 1 0 Solute carrier family 12 RRN3 PF05327.11 CBK21526.2 - 6.7 5.1 11.1 9.2 4.7 11.1 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 DNA_pol_phi PF04931.13 CBK21526.2 - 7.1 4.6 19.6 10 4.1 19.6 1.1 1 0 0 1 1 1 0 DNA polymerase phi SID-1_RNA_chan PF13965.6 CBK21526.2 - 8.1 4.7 5.4 9.5 4.5 5.4 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 MFS_1 PF07690.16 CBK21527.2 - 6.2e-32 110.9 32.5 5.7e-25 88.0 30.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily UPF0542 PF15086.6 CBK21527.2 - 0.004 17.1 0.3 1.6 8.7 0.0 2.8 2 0 0 2 2 2 2 Uncharacterised protein family UPF0542 Connexin PF00029.19 CBK21527.2 - 0.047 13.4 1.5 0.12 12.2 1.5 1.6 1 0 0 1 1 1 0 Connexin Ly49 PF08391.10 CBK21527.2 - 0.061 13.7 0.3 18 5.7 0.0 2.6 2 0 0 2 2 2 0 Ly49-like protein, N-terminal region DUF4731 PF15875.5 CBK21527.2 - 0.31 11.2 3.1 2.4 8.4 3.1 2.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4731) FeoB_associated PF12669.7 CBK21527.2 - 1.5 9.3 7.3 5.9 7.4 0.0 4.3 4 0 0 4 4 4 0 FeoB-associated Cys-rich membrane protein ECSCR PF15820.5 CBK21527.2 - 3.3 7.6 5.4 4 7.3 0.0 2.9 3 0 0 3 3 3 0 Endothelial cell-specific chemotaxis regulator Peptidase_C13 PF01650.18 CBK21528.2 - 4.5e-43 147.6 0.0 5.7e-43 147.3 0.0 1.1 1 0 0 1 1 1 1 Peptidase C13 family Myb_DNA-binding PF00249.31 CBK21529.2 - 0.0045 17.1 0.1 0.0082 16.3 0.1 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain IBD PF10416.9 CBK21529.2 - 0.015 15.3 0.1 0.032 14.3 0.1 1.5 1 0 0 1 1 1 0 Transcription-initiator DNA-binding domain IBD C1_2 PF03107.16 CBK21529.2 - 0.21 11.9 7.7 0.55 10.6 7.7 1.7 1 0 0 1 1 1 0 C1 domain zf-B_box PF00643.24 CBK21529.2 - 0.27 11.4 9.0 0.052 13.7 5.0 1.9 2 0 0 2 2 2 0 B-box zinc finger FYVE PF01363.21 CBK21529.2 - 0.65 10.2 9.2 1.6 8.9 9.2 1.7 1 1 0 1 1 1 0 FYVE zinc finger C1_1 PF00130.22 CBK21529.2 - 0.79 9.7 8.1 1.7 8.6 7.3 2.0 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-RING_5 PF14634.6 CBK21529.2 - 4.4 7.3 10.9 3.5 7.7 8.8 2.0 2 0 0 2 2 2 0 zinc-RING finger domain SWIRM PF04433.17 CBK21530.2 - 7e-06 26.3 0.0 9.8e-06 25.8 0.0 1.2 1 0 0 1 1 1 1 SWIRM domain DUF5546 PF17700.1 CBK21530.2 - 0.051 13.9 0.0 0.053 13.9 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5546) Cytochrom_B_C PF00032.17 CBK21531.2 - 0.014 15.7 1.2 0.016 15.5 1.2 1.1 1 0 0 1 1 1 0 Cytochrome b(C-terminal)/b6/petD Ac76 PF05814.11 CBK21531.2 - 0.022 14.8 6.8 0.037 14.0 6.8 1.5 1 1 0 1 1 1 0 Orf76 (Ac76) DUF2207 PF09972.9 CBK21531.2 - 0.12 11.2 0.1 0.12 11.1 0.1 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Orf78 PF06024.12 CBK21531.2 - 1.1 9.5 8.1 1.4e+02 2.8 8.1 2.1 1 1 0 1 1 1 0 Orf78 (ac78) Spt5-NGN PF03439.13 CBK21532.2 - 0.00017 21.4 0.7 0.0019 18.1 0.0 2.4 2 0 0 2 2 2 1 Early transcription elongation factor of RNA pol II, NGN section ICMT PF04140.14 CBK21532.2 - 0.069 13.6 0.2 0.12 12.8 0.2 1.3 1 0 0 1 1 1 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family 7TM_GPCR_Str PF10326.9 CBK21533.2 - 0.031 13.6 0.6 0.039 13.3 0.6 1.1 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Str EphA2_TM PF14575.6 CBK21533.2 - 0.68 10.9 2.4 1.5 9.8 2.4 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain PelG PF16933.5 CBK21534.2 - 0.18 10.6 0.0 0.24 10.2 0.0 1.1 1 0 0 1 1 1 0 Putative exopolysaccharide Exporter (EPS-E) RRM_1 PF00076.22 CBK21535.2 - 9.8e-07 28.5 0.0 0.0048 16.7 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 CBK21535.2 - 0.043 13.7 0.0 0.069 13.0 0.0 1.3 1 0 0 1 1 1 0 Occluded RNA-recognition motif F_bP_aldolase PF01116.20 CBK21536.2 - 7.4e-82 275.0 0.0 8.6e-82 274.8 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II HAD_2 PF13419.6 CBK21537.2 - 1.9e-08 34.6 0.0 2.6e-08 34.2 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 CBK21537.2 - 3.8e-08 33.3 0.0 7.3e-08 32.4 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.26 CBK21537.2 - 1.1e-06 29.1 0.0 1.9e-06 28.3 0.0 1.6 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Pre-PUA PF17832.1 CBK21537.2 - 0.053 14.2 0.4 0.2 12.3 0.2 2.0 1 1 1 2 2 2 0 Pre-PUA-like domain FeS_assembly_P PF01883.19 CBK21538.2 - 0.0009 19.4 0.2 0.0016 18.6 0.0 1.6 2 0 0 2 2 2 1 Iron-sulfur cluster assembly protein TMF_TATA_bd PF12325.8 CBK21539.2 - 0.0044 17.2 16.9 0.0051 17.0 9.3 2.3 1 1 1 2 2 2 1 TATA element modulatory factor 1 TATA binding HMMR_N PF15905.5 CBK21539.2 - 0.0098 15.4 16.7 0.014 14.9 16.7 1.2 1 0 0 1 1 1 1 Hyaluronan mediated motility receptor N-terminal DUF4472 PF14739.6 CBK21539.2 - 0.035 14.8 14.8 0.26 12.0 4.3 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4472) ATG16 PF08614.11 CBK21539.2 - 0.093 12.9 16.8 0.035 14.3 6.8 2.1 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) DUF3450 PF11932.8 CBK21539.2 - 0.47 9.7 17.3 0.19 11.0 11.4 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) UPF0242 PF06785.11 CBK21539.2 - 1.5 8.8 19.0 14 5.8 19.0 2.0 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus LMBR1 PF04791.16 CBK21539.2 - 3.8 6.3 8.5 4.1 6.2 8.5 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein CENP-H PF05837.12 CBK21539.2 - 4.3 7.8 15.1 0.88 10.0 4.9 2.4 1 1 0 2 2 2 0 Centromere protein H (CENP-H) Thioredoxin PF00085.20 CBK21540.2 - 5.5e-25 87.3 0.1 1.1e-24 86.3 0.1 1.5 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 CBK21540.2 - 0.00096 19.6 0.4 0.048 14.1 0.1 3.0 2 2 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_7 PF13899.6 CBK21540.2 - 0.0045 17.1 0.0 0.0097 16.1 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_6 PF13848.6 CBK21540.2 - 0.0097 15.8 0.0 2.3 8.1 0.0 2.5 3 0 0 3 3 3 2 Thioredoxin-like domain OST3_OST6 PF04756.13 CBK21540.2 - 0.02 14.3 0.1 0.036 13.4 0.0 1.4 1 1 0 1 1 1 0 OST3 / OST6 family, transporter family Thioredoxin_8 PF13905.6 CBK21540.2 - 0.11 12.8 0.1 28 5.1 0.1 2.9 2 1 1 3 3 3 0 Thioredoxin-like Peptidase_M48 PF01435.18 CBK21541.2 - 4.2e-14 52.8 0.6 2.4e-11 43.8 0.6 2.7 1 1 0 1 1 1 1 Peptidase family M48 Rubrerythrin PF02915.17 CBK21541.2 - 0.0061 17.0 0.1 0.16 12.3 0.0 2.1 2 0 0 2 2 2 1 Rubrerythrin CC2-LZ PF16516.5 CBK21541.2 - 0.095 13.1 1.0 0.12 12.8 0.1 1.6 2 0 0 2 2 2 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator Peptidase_M13 PF01431.21 CBK21541.2 - 0.097 12.3 0.1 1.7 8.2 0.0 2.1 2 0 0 2 2 2 0 Peptidase family M13 PFEMP PF03011.15 CBK21542.2 - 0.00092 19.9 1.7 0.0017 19.1 1.7 1.4 1 0 0 1 1 1 1 PFEMP DBL domain THOC7 PF05615.13 CBK21542.2 - 0.0081 16.4 0.7 0.014 15.7 0.7 1.4 1 0 0 1 1 1 1 Tho complex subunit 7 AAA_13 PF13166.6 CBK21542.2 - 0.015 14.0 2.8 0.019 13.6 2.8 1.2 1 0 0 1 1 1 0 AAA domain Med9 PF07544.13 CBK21542.2 - 0.04 14.0 2.1 0.08 13.0 0.8 2.1 2 1 1 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 GOLD_2 PF13897.6 CBK21542.2 - 0.052 14.1 2.7 0.13 12.7 0.0 2.5 2 1 1 3 3 3 0 Golgi-dynamics membrane-trafficking Imm45 PF15572.6 CBK21542.2 - 0.067 13.6 0.0 0.17 12.2 0.0 1.8 1 0 0 1 1 1 0 Immunity protein 45 CENP-H PF05837.12 CBK21542.2 - 0.075 13.4 1.4 0.13 12.7 1.4 1.3 1 0 0 1 1 1 0 Centromere protein H (CENP-H) FCH PF00611.23 CBK21542.2 - 0.12 12.7 0.7 0.42 10.9 0.4 2.1 2 0 0 2 2 2 0 Fes/CIP4, and EFC/F-BAR homology domain DEAD PF00270.29 CBK21543.2 - 5e-48 163.2 1.4 1.3e-47 161.8 0.1 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CBK21543.2 - 3.4e-31 107.8 2.5 1.2e-28 99.7 0.2 3.2 2 1 0 2 2 2 2 Helicase conserved C-terminal domain ResIII PF04851.15 CBK21543.2 - 1.1e-06 28.8 0.0 1.1e-06 28.8 0.0 2.8 3 1 0 3 3 3 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 CBK21543.2 - 0.00012 22.3 1.3 0.00059 20.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain DUF2452 PF10504.9 CBK21543.2 - 0.029 13.8 1.6 0.069 12.6 1.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2452) VPS13_C PF16909.5 CBK21544.2 - 6.7e-52 175.8 8.6 3e-49 167.2 0.1 3.1 3 0 0 3 3 3 2 Vacuolar-sorting-associated 13 protein C-terminal SHR-BD PF06650.12 CBK21544.2 - 2.8e-25 89.2 0.0 2.5e-22 79.6 0.0 2.8 2 0 0 2 2 2 2 SHR-binding domain of vacuolar-sorting associated protein 13 Mak16 PF04874.14 CBK21544.2 - 0.69 10.6 8.4 1.7 9.3 0.0 3.1 2 0 0 2 2 2 0 Mak16 protein C-terminal region UCH PF00443.29 CBK21545.2 - 1.4e-22 80.5 0.0 7.1e-22 78.1 0.0 2.2 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 CBK21545.2 - 2.7e-05 23.9 8.9 0.00028 20.6 0.3 3.3 3 1 0 3 3 3 2 Ubiquitin carboxyl-terminal hydrolase Glycos_transf_2 PF00535.26 CBK21546.2 - 1.2e-18 67.5 0.0 1.9e-18 66.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 CBK21546.2 - 0.00012 22.0 0.0 0.00022 21.2 0.0 1.3 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Ribosomal_S6e PF01092.19 CBK21547.2 - 1e-56 190.3 0.0 1e-56 190.3 0.0 1.5 2 0 0 2 2 2 1 Ribosomal protein S6e He_PIG PF05345.12 CBK21548.2 - 4.7e-12 45.9 15.6 1.7e-06 28.1 0.2 4.0 4 0 0 4 4 4 3 Putative Ig domain ERGIC_N PF13850.6 CBK21548.2 - 0.075 13.4 0.0 0.93 9.9 0.0 2.3 2 0 0 2 2 2 0 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) DUF11 PF01345.18 CBK21548.2 - 0.35 11.2 2.1 22 5.5 0.4 3.1 2 1 0 2 2 2 0 Domain of unknown function DUF11 His_Phos_1 PF00300.22 CBK21549.2 - 2.7e-33 115.3 0.0 8.7e-27 94.1 0.0 2.0 1 1 1 2 2 2 2 Histidine phosphatase superfamily (branch 1) BCAS2 PF05700.11 CBK21550.2 - 4.1e-33 114.8 4.2 4.7e-33 114.6 4.2 1.0 1 0 0 1 1 1 1 Breast carcinoma amplified sequence 2 (BCAS2) CtIP_N PF10482.9 CBK21550.2 - 0.01 15.8 4.6 0.055 13.5 0.9 2.2 2 0 0 2 2 2 0 Tumour-suppressor protein CtIP N-terminal domain Exonuc_VII_L PF02601.15 CBK21550.2 - 0.2 11.2 3.3 0.22 11.1 3.3 1.0 1 0 0 1 1 1 0 Exonuclease VII, large subunit DSS1_SEM1 PF05160.13 CBK21551.2 - 1.1e-17 63.8 13.9 1.4e-17 63.5 13.9 1.1 1 0 0 1 1 1 1 DSS1/SEM1 family DUF2947 PF11163.8 CBK21551.2 - 0.0003 20.7 4.4 0.00033 20.6 4.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2947) Aminotran_1_2 PF00155.21 CBK21552.2 - 1.4e-37 129.8 0.0 1.8e-37 129.4 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 CBK21552.2 - 0.017 14.4 0.0 0.041 13.2 0.0 1.7 2 0 0 2 2 2 0 Beta-eliminating lyase VHP PF02209.19 CBK21554.2 - 7.5e-16 57.9 0.6 2e-15 56.6 0.6 1.8 1 0 0 1 1 1 1 Villin headpiece domain LIM PF00412.22 CBK21555.2 - 1.2e-09 38.2 4.0 1.2e-09 38.2 4.0 2.9 2 1 1 3 3 3 1 LIM domain DUF2685 PF10886.8 CBK21555.2 - 0.0026 17.9 0.6 0.25 11.6 0.0 2.6 2 0 0 2 2 2 2 Protein of unknown function (DUF2685) Pkinase PF00069.25 CBK21556.2 - 1.5e-37 129.4 0.0 1.7e-37 129.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBK21556.2 - 2.7e-23 82.6 0.0 2.9e-23 82.5 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 CBK21556.2 - 4.5e-06 25.9 0.0 6e-06 25.4 0.0 1.1 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 CBK21556.2 - 0.011 15.1 0.0 0.013 14.9 0.0 1.1 1 0 0 1 1 1 0 Kinase-like Pkinase_fungal PF17667.1 CBK21556.2 - 0.014 14.2 0.1 0.016 14.0 0.1 1.1 1 0 0 1 1 1 0 Fungal protein kinase APH PF01636.23 CBK21556.2 - 0.044 13.7 0.5 0.061 13.2 0.5 1.1 1 0 0 1 1 1 0 Phosphotransferase enzyme family Prim_Zn_Ribbon PF08273.12 CBK21557.2 - 0.062 13.6 0.5 0.096 13.0 0.5 1.4 1 1 0 1 1 1 0 Zinc-binding domain of primase-helicase Peptidase_M49 PF03571.15 CBK21558.2 - 2e-203 676.8 0.0 2.4e-203 676.5 0.0 1.0 1 0 0 1 1 1 1 Peptidase family M49 SHS2_Rpb7-N PF03876.17 CBK21559.2 - 1.5e-12 47.7 0.0 2.4e-12 47.0 0.0 1.3 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 Metallothio PF00131.20 CBK21560.2 - 1.8 8.7 71.5 0.063 13.4 25.7 2.4 2 0 0 2 2 2 0 Metallothionein Atx10homo_assoc PF09759.9 CBK21561.2 - 2.5e-29 101.2 1.1 1.1e-28 99.2 0.1 2.3 2 0 0 2 2 2 1 Spinocerebellar ataxia type 10 protein domain ERAP1_C PF11838.8 CBK21561.2 - 0.004 16.7 0.2 0.0069 16.0 0.2 1.3 1 0 0 1 1 1 1 ERAP1-like C-terminal domain zf-DNL PF05180.12 CBK21561.2 - 0.048 13.6 0.4 0.11 12.4 0.4 1.6 1 0 0 1 1 1 0 DNL zinc finger DUF498 PF04430.14 CBK21562.2 - 4.6e-26 91.0 0.0 5.3e-26 90.8 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF498/DUF598) WD40_4 PF16300.5 CBK21563.2 - 3.6e-16 58.8 0.2 7e-16 57.8 0.2 1.5 1 0 0 1 1 1 1 Type of WD40 repeat WD40 PF00400.32 CBK21563.2 - 7.1e-09 36.2 0.3 0.00019 22.1 0.0 3.9 4 0 0 4 4 4 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBK21563.2 - 0.0001 22.5 0.0 0.13 12.6 0.0 2.8 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain DUF4813 PF16072.5 CBK21563.2 - 0.36 10.5 13.2 0.53 9.9 13.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4813) DUF1899 PF08953.11 CBK21564.2 - 8.1e-16 57.7 0.0 9.4e-16 57.4 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1899) tRNA_Me_trans PF03054.16 CBK21565.2 - 2.1e-103 345.8 0.0 2.8e-103 345.5 0.0 1.1 1 0 0 1 1 1 1 tRNA methyl transferase ThiI PF02568.14 CBK21565.2 - 4.2e-07 29.7 0.0 2.8e-06 27.1 0.0 2.0 2 0 0 2 2 2 1 Thiamine biosynthesis protein (ThiI) NAD_synthase PF02540.17 CBK21565.2 - 2.1e-06 27.0 0.0 0.00016 20.9 0.0 2.3 2 0 0 2 2 2 2 NAD synthase Asn_synthase PF00733.21 CBK21565.2 - 0.0051 16.5 0.0 0.0071 16.0 0.0 1.3 1 0 0 1 1 1 1 Asparagine synthase QueC PF06508.13 CBK21565.2 - 0.017 14.6 0.0 0.17 11.4 0.0 2.1 2 0 0 2 2 2 0 Queuosine biosynthesis protein QueC ATP_bind_3 PF01171.20 CBK21565.2 - 0.043 13.6 0.2 9.8 5.9 0.1 2.3 2 0 0 2 2 2 0 PP-loop family Lung_7-TM_R PF06814.13 CBK21566.2 - 9.3e-29 100.6 22.6 1.2e-28 100.2 22.6 1.1 1 0 0 1 1 1 1 Lung seven transmembrane receptor GpcrRhopsn4 PF10192.9 CBK21566.2 - 0.00052 19.5 23.1 0.00052 19.5 23.1 1.5 1 1 0 1 1 1 1 Rhodopsin-like GPCR transmembrane domain PHO4 PF01384.20 CBK21566.2 - 8.8 5.3 9.8 15 4.5 8.7 1.8 1 1 1 2 2 2 0 Phosphate transporter family HD PF01966.22 CBK21567.2 - 0.00024 21.3 0.1 0.00061 20.0 0.1 1.7 1 0 0 1 1 1 1 HD domain PDEase_I PF00233.19 CBK21567.2 - 0.0031 17.3 0.4 0.006 16.3 0.4 1.4 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase HDOD PF08668.12 CBK21567.2 - 0.021 14.3 0.1 0.049 13.1 0.1 1.6 1 1 0 1 1 1 0 HDOD domain DAG_kinase_N PF14513.6 CBK21568.2 - 0.051 13.8 0.2 0.091 13.0 0.2 1.4 1 0 0 1 1 1 0 Diacylglycerol kinase N-terminus Peptidase_M14 PF00246.24 CBK21569.2 - 8e-11 42.3 0.1 1e-08 35.4 0.2 2.4 2 1 0 2 2 2 2 Zinc carboxypeptidase AstE_AspA PF04952.14 CBK21569.2 - 0.0075 15.4 0.0 1.2 8.2 0.0 2.1 2 0 0 2 2 2 2 Succinylglutamate desuccinylase / Aspartoacylase family Ribosomal_S28e PF01200.18 CBK21570.2 - 1.6e-30 104.9 0.9 1.7e-30 104.8 0.9 1.0 1 0 0 1 1 1 1 Ribosomal protein S28e DUF3850 PF12961.7 CBK21570.2 - 0.067 13.2 0.0 0.89 9.6 0.0 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF3850) ABC1 PF03109.16 CBK21571.2 - 5.4e-28 97.6 0.0 9.6e-28 96.7 0.0 1.4 1 0 0 1 1 1 1 ABC1 family Pkinase PF00069.25 CBK21571.2 - 0.0023 17.3 0.0 0.19 11.1 0.0 2.2 1 1 0 1 1 1 1 Protein kinase domain Pox_ser-thr_kin PF05445.11 CBK21571.2 - 0.0028 16.7 0.1 0.0051 15.8 0.1 1.3 1 0 0 1 1 1 1 Poxvirus serine/threonine protein kinase APH PF01636.23 CBK21571.2 - 0.029 14.3 0.0 1.1 9.1 0.1 2.2 2 0 0 2 2 2 0 Phosphotransferase enzyme family Acetyltransf_14 PF03421.16 CBK21571.2 - 0.11 12.5 0.0 0.24 11.4 0.0 1.5 1 0 0 1 1 1 0 YopJ Serine/Threonine acetyltransferase Dynactin_p62 PF05502.13 CBK21572.2 - 4.1e-07 29.1 31.7 1.4e-05 24.1 25.0 2.5 1 1 1 2 2 2 2 Dynactin p62 family Mon1 PF03164.14 CBK21572.2 - 0.0069 15.5 1.4 0.0095 15.1 1.4 1.2 1 0 0 1 1 1 1 Trafficking protein Mon1 Syncollin PF15138.6 CBK21573.2 - 0.14 12.4 1.8 0.17 12.1 0.5 1.7 1 1 1 2 2 2 0 Syncollin UDPGP PF01704.18 CBK21574.2 - 4.1e-11 42.2 0.0 1.1e-10 40.7 0.0 1.6 2 0 0 2 2 2 1 UTP--glucose-1-phosphate uridylyltransferase VP4_helical PF17478.2 CBK21575.2 - 0.063 12.7 0.1 0.11 12.0 0.1 1.3 1 0 0 1 1 1 0 Rotavirus VP4 helical domain ASFV_J13L PF05568.11 CBK21576.2 - 0.032 14.0 0.8 0.054 13.3 0.8 1.3 1 0 0 1 1 1 0 African swine fever virus J13L protein TMEM154 PF15102.6 CBK21576.2 - 0.082 12.8 0.9 0.082 12.8 0.9 2.0 2 0 0 2 2 2 0 TMEM154 protein family DUF4006 PF13179.6 CBK21576.2 - 0.48 10.4 4.3 1.2 9.1 0.1 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF4006) MMS19_C PF12460.8 CBK21577.2 - 0.065 12.3 0.9 0.086 11.9 0.9 1.3 1 1 0 1 1 1 0 RNAPII transcription regulator C-terminal Glyco_hydro_125 PF06824.11 CBK21578.2 - 4e-158 526.7 0.0 4.5e-158 526.5 0.0 1.0 1 0 0 1 1 1 1 Metal-independent alpha-mannosidase (GH125) PT PF04886.12 CBK21579.2 - 0.003 17.0 5.3 0.003 17.0 5.3 3.2 3 0 0 3 3 3 1 PT repeat HSP70 PF00012.20 CBK21579.2 - 2 6.5 8.5 4.1 5.5 8.5 1.4 1 0 0 1 1 1 0 Hsp70 protein Trypan_PARP PF05887.11 CBK21579.2 - 3 7.8 14.1 9.7 6.2 14.1 1.8 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) PIP5K PF01504.18 CBK21580.2 - 3.2e-45 154.5 1.8 1.2e-36 126.3 0.7 2.1 1 1 1 2 2 2 2 Phosphatidylinositol-4-phosphate 5-Kinase DUF1199 PF06712.11 CBK21580.2 - 0.089 12.8 0.1 4.4 7.4 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1199) Cpn60_TCP1 PF00118.24 CBK21581.2 - 1.8e-06 26.9 0.3 1.8e-06 26.9 0.3 1.1 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family FA_desaturase_2 PF03405.14 CBK21581.2 - 0.058 12.2 0.0 0.07 12.0 0.0 1.1 1 0 0 1 1 1 0 Fatty acid desaturase Cpn60_TCP1 PF00118.24 CBK21582.2 - 2.3e-08 33.1 0.0 2.9e-08 32.8 0.0 1.1 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family FYVE PF01363.21 CBK21583.2 - 1.4e-13 50.8 10.8 1.4e-13 50.8 10.8 1.0 1 0 0 1 1 1 1 FYVE zinc finger C1_4 PF07975.12 CBK21583.2 - 0.031 14.5 13.2 0.21 11.8 13.2 2.0 1 1 0 1 1 1 0 TFIIH C1-like domain Zf_RING PF16744.5 CBK21583.2 - 0.12 12.4 8.4 0.16 12.1 8.4 1.3 1 0 0 1 1 1 0 KIAA1045 RING finger ER_lumen_recept PF00810.18 CBK21584.2 - 4.3e-47 160.6 9.6 4.3e-47 160.6 9.6 1.7 2 0 0 2 2 2 1 ER lumen protein retaining receptor PQ-loop PF04193.14 CBK21584.2 - 0.017 14.9 16.9 0.1 12.4 0.7 4.0 4 0 0 4 4 4 0 PQ loop repeat DHHC PF01529.20 CBK21585.2 - 5.5e-32 110.7 8.6 5.5e-32 110.7 8.6 2.2 1 1 1 2 2 2 1 DHHC palmitoyltransferase DUF2207 PF09972.9 CBK21585.2 - 0.18 10.6 1.0 0.25 10.0 1.0 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Mito_carr PF00153.27 CBK21586.2 - 3.7e-67 222.3 1.5 5.6e-27 93.5 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein SF3b1 PF08920.10 CBK21588.2 - 4.2e-24 85.3 5.2 1.7e-23 83.4 4.8 2.2 1 1 0 1 1 1 1 Splicing factor 3B subunit 1 HEAT_2 PF13646.6 CBK21588.2 - 6.9e-12 45.6 2.2 0.095 13.1 0.0 7.2 5 2 1 6 6 6 3 HEAT repeats HEAT PF02985.22 CBK21588.2 - 7.6e-11 41.3 18.3 0.043 14.1 0.1 10.3 11 0 0 11 11 11 2 HEAT repeat HEAT_EZ PF13513.6 CBK21588.2 - 1.2e-09 38.4 6.2 0.002 18.6 0.0 7.7 6 1 1 7 7 7 1 HEAT-like repeat Cnd1 PF12717.7 CBK21588.2 - 5.5e-08 33.0 1.4 1.2 9.1 0.0 6.2 5 1 2 7 7 7 2 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 CBK21588.2 - 1.2e-06 27.3 2.9 0.019 13.5 0.0 3.6 3 1 0 3 3 3 2 Adaptin N terminal region NUC173 PF08161.12 CBK21588.2 - 8.8e-05 22.3 0.3 45 3.6 0.0 5.8 3 1 2 5 5 5 0 NUC173 domain CLASP_N PF12348.8 CBK21588.2 - 0.0003 20.4 0.4 3.9 7.0 0.0 4.3 4 1 0 4 4 4 1 CLASP N terminal Arm PF00514.23 CBK21588.2 - 0.00064 19.7 7.1 17 5.7 0.0 7.0 7 1 1 8 8 8 0 Armadillo/beta-catenin-like repeat Dopey_N PF04118.14 CBK21588.2 - 0.0019 17.4 0.3 0.082 12.0 0.0 2.9 2 1 0 2 2 2 1 Dopey, N-terminal MMS19_C PF12460.8 CBK21588.2 - 0.028 13.5 0.4 3.6 6.6 0.0 3.9 4 1 1 5 5 5 0 RNAPII transcription regulator C-terminal Vac14_Fab1_bd PF12755.7 CBK21588.2 - 0.049 14.2 2.7 50 4.6 0.0 4.7 5 0 0 5 5 5 0 Vacuolar 14 Fab1-binding region LRR_5 PF13306.6 CBK21589.2 - 0.024 14.6 4.1 1.3 9.0 4.1 2.3 1 1 0 1 1 1 0 BspA type Leucine rich repeat region (6 copies) BRCA-2_OB1 PF09103.10 CBK21589.2 - 0.13 12.2 0.0 0.22 11.5 0.0 1.4 1 0 0 1 1 1 0 BRCA2, oligonucleotide/oligosaccharide-binding, domain 1 MORN PF02493.20 CBK21590.2 - 0.0029 17.4 21.7 0.1 12.5 1.5 6.8 7 0 0 7 7 7 4 MORN repeat ERCC4 PF02732.15 CBK21592.2 - 2e-14 54.1 0.0 4.5e-14 53.0 0.0 1.6 1 0 0 1 1 1 1 ERCC4 domain Gtr1_RagA PF04670.12 CBK21595.2 - 1.4e-27 96.6 0.8 1.6e-27 96.4 0.8 1.0 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region tRNA-synt_1f PF01921.18 CBK21595.2 - 0.019 13.9 0.0 0.031 13.2 0.0 1.2 1 0 0 1 1 1 0 tRNA synthetases class I (K) XRN_N PF03159.18 CBK21596.2 - 1e-78 264.1 0.0 1.6e-78 263.5 0.0 1.3 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus XRN_M PF17846.1 CBK21596.2 - 6.8e-65 219.7 9.9 5.6e-48 164.0 1.5 2.6 3 0 0 3 3 3 2 Xrn1 helical domain Peptidase_M20 PF01546.28 CBK21597.2 - 2.3e-17 63.4 0.0 3.5e-17 62.8 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 CBK21597.2 - 0.028 14.4 0.1 0.11 12.4 0.1 2.0 1 1 0 1 1 1 0 Peptidase dimerisation domain Peptidase_M28 PF04389.17 CBK21597.2 - 0.04 13.6 0.0 0.11 12.1 0.0 1.7 2 1 0 2 2 2 0 Peptidase family M28 RhoGAP PF00620.27 CBK21598.2 - 6.8e-21 74.7 0.0 3.9e-16 59.2 0.0 2.4 2 0 0 2 2 2 2 RhoGAP domain Clat_adaptor_s PF01217.20 CBK21599.2 - 2e-09 37.5 0.2 2.3e-09 37.3 0.2 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Ribosomal_L5e PF17144.4 CBK21600.2 - 2.7e-76 255.1 1.2 5.3e-76 254.1 1.2 1.5 1 0 0 1 1 1 1 Ribosomal large subunit proteins 60S L5, and 50S L18 Ribosomal_L18_c PF14204.6 CBK21600.2 - 5e-31 107.5 5.9 1.1e-30 106.4 5.9 1.6 1 0 0 1 1 1 1 Ribosomal L18 C-terminal region Thioredoxin_4 PF13462.6 CBK21601.2 - 0.0033 17.6 0.0 0.038 14.2 0.0 2.1 2 0 0 2 2 2 1 Thioredoxin GILT PF03227.16 CBK21601.2 - 0.018 15.3 0.0 0.048 13.9 0.0 1.8 1 0 0 1 1 1 0 Gamma interferon inducible lysosomal thiol reductase (GILT) DUF2703 PF10865.8 CBK21601.2 - 0.038 14.2 0.6 0.22 11.7 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF2703) TPR_12 PF13424.6 CBK21602.2 - 0.0057 16.9 0.3 0.02 15.2 0.2 1.7 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_2 PF07719.17 CBK21602.2 - 0.01 15.9 0.0 0.095 12.9 0.1 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 CBK21602.2 - 0.012 16.3 0.5 0.012 16.3 0.5 1.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.28 CBK21602.2 - 0.075 12.9 0.0 0.17 11.7 0.0 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_8 PF13181.6 CBK21602.2 - 0.51 10.7 3.0 1.7 9.0 0.1 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat AAA_lid_9 PF17871.1 CBK21602.2 - 7.6 6.5 9.4 0.48 10.4 0.3 2.3 1 1 0 2 2 2 0 AAA lid domain DHHC PF01529.20 CBK21603.2 - 3.1 7.9 26.1 0.03 14.4 6.0 2.8 1 1 1 2 2 2 0 DHHC palmitoyltransferase Peptidase_M99_C PF17129.4 CBK21604.2 - 0.058 13.6 0.1 0.21 11.8 0.1 1.9 1 0 0 1 1 1 0 C-terminal domain of metallo-carboxypeptidase DnaJ_CXXCXGXG PF00684.19 CBK21605.2 - 0.00019 21.7 25.5 0.00036 20.8 23.6 2.5 1 1 1 2 2 2 1 DnaJ central domain DUF5351 PF17302.2 CBK21605.2 - 5.3 7.3 27.2 1.6 9.0 2.9 4.5 4 0 0 4 4 4 0 Family of unknown function (DUF5351) DUF3591 PF12157.8 CBK21607.2 - 2.5e-28 98.9 0.3 3.8e-22 78.6 0.1 2.7 1 1 1 2 2 2 2 Protein of unknown function (DUF3591) Bromodomain PF00439.25 CBK21607.2 - 1.5e-10 41.0 0.0 6.4e-10 39.0 0.0 2.1 1 0 0 1 1 1 1 Bromodomain Phage_sheath_1C PF17482.2 CBK21607.2 - 0.14 12.2 0.8 25 4.9 0.0 2.7 3 0 0 3 3 3 0 Phage tail sheath C-terminal domain Flt3_lig PF02947.14 CBK21607.2 - 1.4 9.1 4.2 1.9 8.6 0.1 2.9 4 0 0 4 4 4 0 flt3 ligand DEAD PF00270.29 CBK21609.2 - 5.4e-17 62.1 0.0 1.8e-16 60.4 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CBK21609.2 - 1.3e-06 28.7 0.0 6.2e-06 26.5 0.0 2.0 1 1 1 2 2 2 1 Helicase conserved C-terminal domain RecQ_Zn_bind PF16124.5 CBK21609.2 - 0.00069 20.3 0.8 0.0026 18.5 0.8 2.0 1 0 0 1 1 1 1 RecQ zinc-binding ResIII PF04851.15 CBK21609.2 - 0.00077 19.5 0.0 0.0027 17.7 0.0 1.9 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 CBK21609.2 - 0.069 13.4 0.1 0.61 10.4 0.0 2.5 3 1 0 3 3 3 0 AAA domain DUF2703 PF10865.8 CBK21609.2 - 0.1 12.8 1.6 1.1 9.4 0.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF2703) Tox-PLDMTX PF15645.6 CBK21609.2 - 0.17 12.2 0.3 14 5.9 0.0 2.8 1 1 2 3 3 3 0 Dermonecrotoxin of the Papain-like fold LRR_8 PF13855.6 CBK21610.2 - 0.064 13.0 0.3 0.62 9.9 0.0 2.6 3 0 0 3 3 3 0 Leucine rich repeat AMP-binding PF00501.28 CBK21611.2 - 1.1e-81 274.6 0.0 1.3e-81 274.3 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AAA_23 PF13476.6 CBK21612.2 - 1.5e-29 103.9 0.1 1.8e-29 103.7 0.1 1.0 1 0 0 1 1 1 1 AAA domain SMC_N PF02463.19 CBK21612.2 - 1.7e-06 27.6 0.0 3.4e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 CBK21612.2 - 3.1e-06 27.2 2.2 6.1e-06 26.2 2.2 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_21 PF13304.6 CBK21612.2 - 3.6e-05 23.7 0.0 4.1e-05 23.5 0.0 1.4 1 1 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system ABC_tran PF00005.27 CBK21612.2 - 3.8e-05 24.2 0.0 6.8e-05 23.4 0.0 1.4 1 1 0 1 1 1 1 ABC transporter AAA_29 PF13555.6 CBK21612.2 - 0.006 16.3 0.0 0.012 15.4 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.6 CBK21612.2 - 0.015 15.7 0.0 0.034 14.5 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 CBK21612.2 - 0.057 13.7 0.1 0.089 13.1 0.1 1.5 1 1 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 CBK21612.2 - 0.12 11.6 0.0 0.63 9.3 0.0 2.0 2 1 0 2 2 2 0 Zeta toxin AAA_25 PF13481.6 CBK21612.2 - 0.14 11.7 0.0 0.27 10.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain SMC_N PF02463.19 CBK21613.2 - 3.5e-07 29.9 0.2 8e-07 28.7 0.2 1.5 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SbcCD_C PF13558.6 CBK21613.2 - 6.9e-07 29.4 0.2 2.2e-06 27.8 0.0 1.9 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_15 PF13175.6 CBK21613.2 - 4.5e-05 23.3 0.2 5.9e-05 22.9 0.2 1.1 1 0 0 1 1 1 1 AAA ATPase domain AAA_21 PF13304.6 CBK21613.2 - 6.3e-05 22.9 0.0 0.00013 21.9 0.0 1.6 1 1 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system ABC_tran PF00005.27 CBK21613.2 - 0.057 13.9 0.0 0.13 12.8 0.0 1.7 1 1 0 1 1 1 0 ABC transporter KH_8 PF17903.1 CBK21614.2 - 3.5e-32 110.3 0.1 8.2e-32 109.1 0.1 1.7 1 0 0 1 1 1 1 Krr1 KH1 domain Pfg27 PF09216.10 CBK21614.2 - 0.023 14.5 0.5 0.081 12.8 0.1 2.0 2 0 0 2 2 2 0 Pfg27 HSP90 PF00183.18 CBK21615.2 - 8.4e-227 754.1 26.5 1.1e-226 753.8 26.5 1.1 1 0 0 1 1 1 1 Hsp90 protein HATPase_c PF02518.26 CBK21615.2 - 2.1e-15 57.2 0.1 3.9e-15 56.3 0.1 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 CBK21615.2 - 1.1e-10 41.5 0.1 2.7e-10 40.2 0.1 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Sulfatase_C PF14707.6 CBK21615.2 - 0.2 12.4 0.1 0.2 12.4 0.1 2.2 2 0 0 2 2 2 0 C-terminal region of aryl-sulfatase TPR_14 PF13428.6 CBK21616.2 - 4.1e-06 27.2 20.4 0.077 13.8 0.0 7.8 4 1 2 7 7 7 2 Tetratricopeptide repeat Tnp_zf-ribbon_2 PF13842.6 CBK21616.2 - 0.011 16.5 0.2 0.034 15.0 0.2 1.9 1 0 0 1 1 1 0 DDE_Tnp_1-like zinc-ribbon TPR_4 PF07721.14 CBK21616.2 - 7.1 7.6 9.4 10 7.1 0.2 4.4 3 0 0 3 3 3 0 Tetratricopeptide repeat Sigma54_CBD PF04963.13 CBK21617.2 - 0.02 14.7 0.5 0.026 14.4 0.5 1.1 1 0 0 1 1 1 0 Sigma-54 factor, core binding domain DUF1967 PF09269.11 CBK21617.2 - 0.032 14.2 1.8 0.083 12.8 0.3 2.0 1 1 0 2 2 2 0 Domain of unknown function (DUF1967) DUF2098 PF09871.9 CBK21617.2 - 0.17 12.3 4.3 0.25 11.7 4.4 1.3 1 1 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2098) DUF4094 PF13334.6 CBK21617.2 - 0.25 11.8 2.5 3.6 8.1 0.2 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4094) DUF4337 PF14235.6 CBK21617.2 - 0.9 9.6 3.7 1 9.4 3.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) DUF2721 PF11026.8 CBK21617.2 - 1.8 8.4 6.1 1.1 9.1 3.7 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF2721) PIEZO PF15917.5 CBK21617.2 - 2.6 7.4 8.4 1.7 8.0 6.7 1.4 1 1 0 1 1 1 0 Piezo Spc7 PF08317.11 CBK21618.2 - 0.007 15.3 4.4 0.007 15.3 4.4 1.7 1 1 1 2 2 2 1 Spc7 kinetochore protein Baculo_PEP_C PF04513.12 CBK21618.2 - 0.023 14.8 5.0 0.072 13.1 0.8 2.4 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Exonuc_VII_L PF02601.15 CBK21618.2 - 0.076 12.6 3.4 1.3 8.5 1.2 1.9 1 1 1 2 2 2 0 Exonuclease VII, large subunit DUF1690 PF07956.11 CBK21618.2 - 0.097 13.1 7.0 6.8 7.1 5.3 2.2 1 1 1 2 2 2 0 Protein of Unknown function (DUF1690) TMPIT PF07851.13 CBK21618.2 - 0.14 11.4 3.6 0.079 12.2 0.3 1.8 1 1 1 2 2 2 0 TMPIT-like protein RAMPs PF03787.15 CBK21618.2 - 0.17 11.9 0.0 0.21 11.6 0.0 1.2 1 0 0 1 1 1 0 RAMP superfamily BLOC1_2 PF10046.9 CBK21618.2 - 0.23 11.8 6.4 0.4 11.0 0.5 3.2 2 2 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 V-SNARE PF05008.15 CBK21618.2 - 0.3 11.5 9.3 1.2 9.6 0.6 3.5 3 0 0 3 3 3 0 Vesicle transport v-SNARE protein N-terminus Mod_r PF07200.13 CBK21618.2 - 0.3 11.2 8.7 0.21 11.7 5.6 1.9 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein ADIP PF11559.8 CBK21618.2 - 0.34 11.0 6.0 0.71 10.0 4.7 2.0 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding Fib_alpha PF08702.10 CBK21618.2 - 0.49 10.6 8.7 0.84 9.8 2.6 2.6 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family K-box PF01486.17 CBK21618.2 - 0.56 10.4 6.5 0.71 10.1 0.8 3.0 2 2 0 2 2 2 0 K-box region CCDC-167 PF15188.6 CBK21618.2 - 0.69 10.3 6.0 1.1 9.6 1.4 2.7 1 1 1 2 2 2 0 Coiled-coil domain-containing protein 167 DUF3450 PF11932.8 CBK21618.2 - 0.79 9.0 5.9 0.43 9.9 0.6 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) Spc24 PF08286.11 CBK21618.2 - 6.1 7.1 7.3 7.5 6.9 1.2 2.6 1 1 2 3 3 3 0 Spc24 subunit of Ndc80 CHCH PF06747.13 CBK21619.2 - 0.049 13.8 4.5 3.3 7.9 0.4 2.4 2 0 0 2 2 2 0 CHCH domain Glyco_hydro_99 PF16317.5 CBK21620.2 - 3.4e-130 434.2 8.5 3.8e-130 434.0 8.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 99 Glyco_hydro_71 PF03659.14 CBK21620.2 - 5.3e-07 28.8 0.2 9.7e-07 27.9 0.2 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 71 Glyco_tran_WbsX PF14307.6 CBK21620.2 - 0.4 10.1 9.5 0.046 13.2 0.8 2.6 2 1 0 2 2 2 0 Glycosyltransferase WbsX DNA_pol_A_exo1 PF01612.20 CBK21621.2 - 4.3e-19 68.9 0.1 8.1e-19 68.0 0.1 1.4 1 0 0 1 1 1 1 3'-5' exonuclease HRDC PF00570.23 CBK21621.2 - 6.7e-08 32.4 0.1 1.3e-07 31.5 0.1 1.5 1 0 0 1 1 1 1 HRDC domain Imm31 PF15591.6 CBK21621.2 - 0.15 12.0 0.0 0.33 10.8 0.0 1.5 1 0 0 1 1 1 0 Immunity protein 31 ALG11_N PF15924.5 CBK21623.2 - 1.9e-79 266.6 0.8 2.3e-79 266.3 0.8 1.1 1 0 0 1 1 1 1 ALG11 mannosyltransferase N-terminus Glycos_transf_1 PF00534.20 CBK21624.2 - 2.4e-14 53.3 0.0 3e-14 52.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 CBK21624.2 - 3.8e-07 30.6 0.1 5.2e-07 30.2 0.1 1.4 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 CBK21624.2 - 4.2e-05 23.9 0.0 8.6e-05 22.9 0.0 1.5 1 1 0 1 1 1 1 Glycosyl transferases group 1 PUF PF00806.19 CBK21625.2 - 5.7e-14 50.9 1.4 0.062 13.0 0.1 5.6 5 0 0 5 5 5 5 Pumilio-family RNA binding repeat MgsA_C PF12002.8 CBK21625.2 - 0.074 13.0 0.2 0.19 11.7 0.2 1.6 1 0 0 1 1 1 0 MgsA AAA+ ATPase C terminal Peptidase_C92 PF05708.12 CBK21625.2 - 0.092 12.8 0.0 0.23 11.5 0.0 1.6 2 0 0 2 2 2 0 Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family Cpn60_TCP1 PF00118.24 CBK21626.2 - 1.1e-139 466.3 3.4 1.7e-139 465.7 3.4 1.3 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family IF4E PF01652.18 CBK21627.2 - 3.4e-26 91.9 3.5 5.3e-26 91.3 3.5 1.3 1 1 0 1 1 1 1 Eukaryotic initiation factor 4E Suf PF05843.14 CBK21628.2 - 1e-23 84.8 2.2 3.6e-21 76.4 0.0 3.4 2 1 1 3 3 3 1 Suppressor of forked protein (Suf) TPR_19 PF14559.6 CBK21628.2 - 0.0013 19.2 0.7 0.013 16.0 0.0 2.5 2 1 1 3 3 3 1 Tetratricopeptide repeat DUF1360 PF07098.11 CBK21628.2 - 0.14 12.1 0.8 0.44 10.5 0.8 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1360) HAT PF02184.16 CBK21628.2 - 0.43 10.6 5.0 11 6.1 0.0 3.2 3 0 0 3 3 3 0 HAT (Half-A-TPR) repeat Peptidase_C1 PF00112.23 CBK21629.2 - 2.8e-95 318.5 24.8 5.7e-51 173.7 9.1 2.0 2 0 0 2 2 2 2 Papain family cysteine protease UFC1 PF08694.11 CBK21629.2 - 0.84 9.3 3.0 9.8 5.8 0.0 3.2 3 0 0 3 3 3 0 Ubiquitin-fold modifier-conjugating enzyme 1 HhH-GPD PF00730.25 CBK21630.2 - 1.1e-18 67.6 0.0 2e-18 66.8 0.0 1.4 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 CBK21630.2 - 6.7e-10 38.3 0.8 3e-09 36.3 0.1 2.3 2 0 0 2 2 2 1 Helix-hairpin-helix motif EndIII_4Fe-2S PF10576.9 CBK21630.2 - 0.00033 20.9 3.6 0.00033 20.9 3.6 2.0 2 0 0 2 2 2 1 Iron-sulfur binding domain of endonuclease III HHH_2 PF12826.7 CBK21630.2 - 0.00096 19.2 0.1 1.3 9.2 0.0 2.8 3 0 0 3 3 3 2 Helix-hairpin-helix motif HHH_8 PF14716.6 CBK21630.2 - 0.042 14.2 0.0 0.28 11.6 0.0 2.3 2 0 0 2 2 2 0 Helix-hairpin-helix domain HHH_5 PF14520.6 CBK21630.2 - 0.062 13.9 0.0 0.19 12.4 0.0 1.8 1 0 0 1 1 1 0 Helix-hairpin-helix domain Med12-PQL PF12144.8 CBK21630.2 - 0.13 12.1 0.2 0.21 11.5 0.2 1.3 1 0 0 1 1 1 0 Eukaryotic Mediator 12 catenin-binding domain HHH_3 PF12836.7 CBK21630.2 - 0.14 12.5 0.0 0.32 11.3 0.0 1.6 1 0 0 1 1 1 0 Helix-hairpin-helix motif YyzF PF14116.6 CBK21630.2 - 0.63 10.1 0.0 0.63 10.1 0.0 2.6 3 0 0 3 3 3 0 YyzF-like protein Asp_Glu_race PF01177.22 CBK21631.2 - 2e-11 44.2 0.0 2.6e-11 43.8 0.0 1.1 1 0 0 1 1 1 1 Asp/Glu/Hydantoin racemase Flavodoxin_1 PF00258.25 CBK21632.2 - 1e-21 77.6 0.1 1.3e-21 77.3 0.1 1.1 1 0 0 1 1 1 1 Flavodoxin Flavodoxin_5 PF12724.7 CBK21632.2 - 0.053 13.8 0.0 8.3 6.6 0.0 2.2 2 0 0 2 2 2 0 Flavodoxin domain He_PIG PF05345.12 CBK21633.2 - 1.7e-15 56.9 29.3 5.2e-05 23.3 0.1 5.5 5 1 0 5 5 5 4 Putative Ig domain DUF11 PF01345.18 CBK21633.2 - 4.6e-05 23.6 0.0 0.44 10.9 0.0 4.1 2 2 1 3 3 3 2 Domain of unknown function DUF11 I-set PF07679.16 CBK21633.2 - 6.7e-05 22.9 4.9 2 8.5 0.1 4.4 4 0 0 4 4 4 2 Immunoglobulin I-set domain HRM PF02793.22 CBK21633.2 - 0.00053 20.2 13.8 0.29 11.5 0.1 5.2 5 0 0 5 5 5 2 Hormone receptor domain ComP_DUS PF16732.5 CBK21633.2 - 0.022 15.6 1.5 47 5.0 0.0 3.9 4 0 0 4 4 4 0 Type IV minor pilin ComP, DNA uptake sequence receptor DUF3185 PF11381.8 CBK21633.2 - 0.87 9.6 7.8 2.4 8.3 7.8 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3185) Arch_flagellin PF01917.16 CBK21633.2 - 2.8 8.1 8.3 1.5 9.0 1.2 3.1 2 1 1 3 3 3 0 Archaebacterial flagellin DUF1336 PF07059.12 CBK21634.2 - 2.1e-12 47.6 0.0 2.5e-12 47.4 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1336) RhoGAP PF00620.27 CBK21635.2 - 6.3e-13 48.8 0.0 1e-12 48.1 0.0 1.3 1 0 0 1 1 1 1 RhoGAP domain Exo_endo_phos PF03372.23 CBK21635.2 - 0.00018 21.1 0.0 0.00071 19.2 0.0 1.9 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family AAA_12 PF13087.6 CBK21636.2 - 1.3e-26 93.4 0.0 1.6e-26 93.2 0.0 1.1 1 0 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.6 CBK21636.2 - 9e-05 22.2 0.1 0.00016 21.5 0.1 1.4 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain PRP38 PF03371.15 CBK21636.2 - 0.058 13.3 0.1 0.085 12.7 0.1 1.3 1 0 0 1 1 1 0 PRP38 family Viral_helicase1 PF01443.18 CBK21636.2 - 0.15 11.8 0.0 0.16 11.7 0.0 1.2 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Pkinase PF00069.25 CBK21637.2 - 1.4e-66 224.6 0.0 1.7e-66 224.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBK21637.2 - 4.7e-32 111.3 0.0 6.2e-32 110.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CBK21637.2 - 0.0001 21.8 0.0 0.00084 18.7 0.0 1.9 2 0 0 2 2 2 1 Kinase-like FTA2 PF13095.6 CBK21637.2 - 0.033 13.8 0.0 0.37 10.4 0.0 2.0 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 B56 PF01603.20 CBK21639.2 - 5.9e-101 338.4 1.0 6.5e-101 338.3 1.0 1.0 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) Catalase-rel PF06628.12 CBK21639.2 - 0.16 12.2 0.0 14 6.0 0.0 2.7 3 0 0 3 3 3 0 Catalase-related immune-responsive HSP70 PF00012.20 CBK21640.2 - 3.6e-07 28.8 0.0 3.6e-07 28.8 0.0 1.5 2 0 0 2 2 2 1 Hsp70 protein NT-C2 PF10358.9 CBK21640.2 - 0.022 14.5 0.0 0.06 13.1 0.0 1.7 1 0 0 1 1 1 0 N-terminal C2 in EEIG1 and EHBP1 proteins Delta_lysin PF05372.11 CBK21640.2 - 0.054 12.8 0.2 0.12 11.7 0.2 1.5 1 0 0 1 1 1 0 Delta lysin family Ribosomal_S3_C PF00189.20 CBK21641.2 - 8.3e-23 80.7 1.0 1.6e-22 79.8 1.0 1.5 1 0 0 1 1 1 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.17 CBK21641.2 - 6.7e-11 41.9 0.2 1.2e-10 41.0 0.2 1.5 1 0 0 1 1 1 1 KH domain UN_NPL4 PF11543.8 CBK21641.2 - 0.015 15.8 0.0 0.029 14.8 0.0 1.6 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 SHMT PF00464.19 CBK21642.2 - 2.9e-177 589.2 0.0 3.4e-177 589.0 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Beta_elim_lyase PF01212.21 CBK21642.2 - 0.0028 17.0 0.0 0.0099 15.2 0.0 1.8 1 1 0 1 1 1 1 Beta-eliminating lyase Macro PF01661.21 CBK21642.2 - 0.017 15.2 0.0 0.033 14.2 0.0 1.6 1 0 0 1 1 1 0 Macro domain LSM PF01423.22 CBK21643.2 - 1.4e-09 37.5 0.0 1.6e-09 37.3 0.0 1.1 1 0 0 1 1 1 1 LSM domain PCIF1_WW PF12237.8 CBK21644.2 - 4.8e-42 143.5 1.3 4.8e-42 143.5 1.3 1.5 2 0 0 2 2 2 1 Phosphorylated CTD interacting factor 1 WW domain RMMBL PF07521.12 CBK21645.2 - 2.4e-07 30.6 0.0 4.6e-07 29.7 0.0 1.5 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain CPSF100_C PF13299.6 CBK21645.2 - 5.4e-05 23.4 0.2 0.026 14.7 0.0 2.6 2 1 0 3 3 3 2 Cleavage and polyadenylation factor 2 C-terminal Lactamase_B_6 PF16661.5 CBK21646.2 - 9e-45 152.5 0.0 1.8e-44 151.5 0.0 1.5 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily domain Beta-Casp PF10996.8 CBK21646.2 - 5.2e-13 49.2 0.0 9.8e-13 48.4 0.0 1.5 1 0 0 1 1 1 1 Beta-Casp domain Lactamase_B PF00753.27 CBK21646.2 - 0.002 18.1 0.0 0.0037 17.3 0.0 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 CBK21646.2 - 0.014 14.9 0.0 0.031 13.8 0.0 1.5 1 0 0 1 1 1 0 Beta-lactamase superfamily domain PI3_PI4_kinase PF00454.27 CBK21649.2 - 1.8e-43 149.2 0.0 2.4e-43 148.8 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.20 CBK21649.2 - 1.2e-14 53.8 0.0 2.9e-14 52.6 0.0 1.7 1 0 0 1 1 1 1 FATC domain DUF4135 PF13575.6 CBK21649.2 - 0.092 12.1 0.0 0.12 11.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4135) WW PF00397.26 CBK21650.2 - 7.2e-07 29.2 13.4 0.00034 20.6 1.6 3.1 3 0 0 3 3 3 2 WW domain Rubredoxin_2 PF18073.1 CBK21650.2 - 0.027 14.2 6.4 0.027 14.2 6.4 2.7 3 0 0 3 3 3 0 Rubredoxin metal binding domain Colicin_Pyocin PF01320.18 CBK21650.2 - 0.1 12.7 0.0 0.4 10.8 0.0 2.0 1 0 0 1 1 1 0 Colicin immunity protein / pyocin immunity protein RecR PF02132.15 CBK21650.2 - 6 6.5 14.5 1.4 8.6 0.6 4.2 4 0 0 4 4 4 0 RecR protein Ureide_permease PF07168.11 CBK21651.2 - 2.1e-08 33.3 1.1 2.1e-08 33.3 1.1 1.0 1 0 0 1 1 1 1 Ureide permease Sugar_transport PF06800.12 CBK21651.2 - 6.3e-08 32.3 0.3 7.7e-08 32.0 0.3 1.0 1 0 0 1 1 1 1 Sugar transport protein TMEM144 PF07857.12 CBK21651.2 - 0.00015 20.9 0.5 0.00017 20.7 0.5 1.0 1 0 0 1 1 1 1 Transmembrane family, TMEM144 of transporters Tmemb_14 PF03647.13 CBK21651.2 - 0.19 12.5 4.4 0.28 11.9 4.4 1.3 1 0 0 1 1 1 0 Transmembrane proteins 14C Ureide_permease PF07168.11 CBK21652.2 - 0.00011 21.1 0.0 0.00012 20.9 0.0 1.2 1 0 0 1 1 1 1 Ureide permease Shisa PF13908.6 CBK21652.2 - 7.9 6.7 7.5 1 9.6 1.8 2.0 1 1 1 2 2 2 0 Wnt and FGF inhibitory regulator adh_short PF00106.25 CBK21653.2 - 7.5e-20 71.2 0.1 1e-19 70.8 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CBK21653.2 - 8.9e-09 35.2 0.1 1e-08 35.0 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase tRNA-synt_2 PF00152.20 CBK21654.2 - 7.8e-70 235.4 0.0 1.2e-69 234.8 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) WHEP-TRS PF00458.20 CBK21654.2 - 1.3e-13 50.9 2.5 1.3e-13 50.9 2.5 2.0 2 0 0 2 2 2 1 WHEP-TRS domain tRNA_anti-codon PF01336.25 CBK21654.2 - 9.5e-08 31.9 0.3 1.7e-07 31.1 0.3 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 CBK21654.2 - 0.00025 20.6 0.1 0.18 11.3 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) Peptidase_C27 PF05407.12 CBK21654.2 - 0.085 12.9 0.1 0.15 12.1 0.1 1.3 1 0 0 1 1 1 0 Rubella virus endopeptidase DUF383 PF04063.14 CBK21655.2 - 3e-23 82.5 4.3 1.5e-22 80.2 0.4 2.7 2 1 1 3 3 3 1 Domain of unknown function (DUF383) DUF384 PF04064.13 CBK21655.2 - 2e-14 53.2 0.4 6.5e-14 51.5 0.4 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF384) Cnd1 PF12717.7 CBK21655.2 - 0.00082 19.5 2.1 0.0023 18.0 0.9 2.3 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 CBK21655.2 - 0.018 15.5 0.1 0.4 11.1 0.1 2.8 2 1 0 2 2 2 0 HEAT repeats HEAT PF02985.22 CBK21655.2 - 0.02 15.1 0.2 0.16 12.3 0.1 2.6 2 0 0 2 2 2 0 HEAT repeat Proteasom_PSMB PF10508.9 CBK21655.2 - 1.4 7.3 5.5 1.5 7.3 2.2 2.2 2 1 1 3 3 3 0 Proteasome non-ATPase 26S subunit 4HBT_2 PF13279.6 CBK21656.2 - 4e-09 37.0 0.0 4.8e-09 36.8 0.0 1.2 1 0 0 1 1 1 1 Thioesterase-like superfamily 4HBT PF03061.22 CBK21656.2 - 2.5e-07 30.9 0.0 3.7e-07 30.4 0.0 1.3 1 0 0 1 1 1 1 Thioesterase superfamily Acyl-ACP_TE PF01643.17 CBK21656.2 - 0.016 14.5 0.8 0.11 11.8 0.3 2.0 2 0 0 2 2 2 0 Acyl-ACP thioesterase YIF1 PF03878.15 CBK21657.2 - 2.6e-50 171.2 5.4 3.5e-50 170.8 5.4 1.1 1 0 0 1 1 1 1 YIF1 Polysacc_synt PF01943.17 CBK21657.2 - 0.00069 19.1 5.4 0.023 14.1 3.2 2.2 2 0 0 2 2 2 2 Polysaccharide biosynthesis protein Yip1 PF04893.17 CBK21657.2 - 0.0017 18.1 5.6 0.0026 17.5 5.6 1.3 1 0 0 1 1 1 1 Yip1 domain CorA PF01544.18 CBK21658.2 - 1.7e-35 122.7 0.2 2.2e-35 122.4 0.2 1.1 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein Fib_alpha PF08702.10 CBK21658.2 - 0.028 14.6 1.0 0.49 10.6 0.8 2.3 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family ETRAMP PF09716.10 CBK21658.2 - 0.12 12.4 0.0 0.25 11.4 0.0 1.6 1 1 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) EF-hand_8 PF13833.6 CBK21659.2 - 3.7e-11 42.7 1.1 4.1e-05 23.3 0.1 2.0 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 CBK21659.2 - 5.1e-11 41.3 0.8 9.4e-06 24.8 0.2 2.2 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 CBK21659.2 - 8.7e-11 40.9 0.7 8.5e-07 28.4 0.2 2.2 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 CBK21659.2 - 2e-10 39.7 0.1 4.1e-06 26.1 0.2 2.3 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 CBK21659.2 - 3.6e-09 36.9 0.8 2.5e-08 34.2 1.0 1.8 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_10 PF14788.6 CBK21659.2 - 0.013 15.4 0.2 0.023 14.5 0.1 1.4 1 1 1 2 2 2 0 EF hand SPARC_Ca_bdg PF10591.9 CBK21659.2 - 0.024 15.0 0.0 0.028 14.7 0.0 1.1 1 0 0 1 1 1 0 Secreted protein acidic and rich in cysteine Ca binding region DUF3215 PF11503.8 CBK21659.2 - 0.034 14.0 0.1 0.041 13.7 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3215) EF-hand_11 PF08976.11 CBK21659.2 - 0.052 14.4 0.1 0.061 14.2 0.1 1.0 1 0 0 1 1 1 0 EF-hand domain EF-hand_9 PF14658.6 CBK21659.2 - 0.086 13.2 0.0 0.095 13.0 0.0 1.1 1 0 0 1 1 1 0 EF-hand domain Mito_carr PF00153.27 CBK21660.2 - 2.4e-56 187.7 6.9 4.5e-23 81.0 0.2 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 CBK21660.2 - 0.11 11.6 0.5 0.6 9.2 0.1 2.3 2 1 1 3 3 3 0 Gammaproteobacterial serine protease RRM_1 PF00076.22 CBK21663.2 - 1.7e-25 88.6 0.0 5.3e-16 58.2 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CBK21663.2 - 0.00073 19.6 0.0 0.0019 18.2 0.0 1.8 1 1 0 1 1 1 1 RNA recognition motif RRM_3 PF08777.11 CBK21663.2 - 0.027 14.5 0.0 1.5 8.9 0.0 2.2 2 0 0 2 2 2 0 RNA binding motif NosL PF05573.12 CBK21664.2 - 0.15 12.4 0.0 3.7 7.9 0.0 2.2 2 0 0 2 2 2 0 NosL Pkinase PF00069.25 CBK21665.2 - 3e-30 105.5 0.0 3.1e-30 105.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBK21665.2 - 1.7e-16 60.3 0.0 1.9e-16 60.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CBK21665.2 - 0.0043 16.4 0.0 0.0083 15.5 0.0 1.5 1 1 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 CBK21665.2 - 0.0051 15.6 0.0 0.0074 15.1 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 CBK21665.2 - 0.013 14.9 0.0 0.023 14.1 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 CBK21665.2 - 0.014 14.4 0.1 0.02 13.8 0.1 1.2 1 0 0 1 1 1 0 Haspin like kinase domain APH PF01636.23 CBK21665.2 - 0.054 13.4 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.11 CBK21665.2 - 0.073 12.0 0.0 0.11 11.4 0.0 1.3 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Calreticulin PF00262.18 CBK21666.2 - 7.1e-86 288.3 14.8 5.6e-60 203.1 6.1 2.1 1 1 1 2 2 2 2 Calreticulin family Ank_4 PF13637.6 CBK21667.2 - 1e-12 48.3 0.0 3.7e-07 30.6 0.0 2.6 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 CBK21667.2 - 2e-10 41.1 0.0 9.2e-10 39.0 0.0 1.8 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 CBK21667.2 - 9.1e-09 35.4 0.0 2.2e-05 24.6 0.0 2.3 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 CBK21667.2 - 1.5e-08 34.7 0.0 0.041 14.4 0.1 3.3 3 0 0 3 3 3 3 Ankyrin repeat Ank_3 PF13606.6 CBK21667.2 - 1.2e-06 28.3 0.0 0.084 13.5 0.0 3.7 3 1 0 3 3 3 2 Ankyrin repeat Sdh_cyt PF01127.22 CBK21668.2 - 1.2e-12 47.9 3.9 1.8e-12 47.3 3.9 1.2 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit Ribosomal_L40e PF01020.17 CBK21669.2 - 4.1e-29 100.2 13.8 4.1e-29 100.2 13.8 1.7 2 0 0 2 2 2 1 Ribosomal L40e family ubiquitin PF00240.23 CBK21669.2 - 7.5e-18 64.1 0.0 1e-17 63.7 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 CBK21669.2 - 6.7e-10 38.7 0.1 1e-09 38.1 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Spec3 PF15795.5 CBK21671.2 - 1e-06 29.2 13.8 0.00078 19.9 5.1 2.0 1 1 1 2 2 2 2 Ectodermal ciliogenesis protein Meleagrin PF08189.11 CBK21671.2 - 0.035 13.8 4.4 0.054 13.2 4.4 1.2 1 0 0 1 1 1 0 Meleagrin/Cygnin family Pmp3 PF01679.17 CBK21671.2 - 1.3 9.3 6.6 3.3 8.0 6.6 1.8 1 1 0 1 1 1 0 Proteolipid membrane potential modulator TM2 PF05154.16 CBK21671.2 - 5 7.5 11.6 0.29 11.5 3.5 2.0 2 0 0 2 2 2 0 TM2 domain Pep_deformylase PF01327.21 CBK21672.2 - 5.2e-30 104.2 0.0 9.1e-30 103.4 0.0 1.4 1 0 0 1 1 1 1 Polypeptide deformylase DUF4368 PF14287.6 CBK21672.2 - 0.073 13.4 0.2 0.17 12.2 0.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4368) zf-CHCC PF10276.9 CBK21673.2 - 1.2e-11 44.5 3.9 1.7e-11 44.0 3.9 1.2 1 0 0 1 1 1 1 Zinc-finger domain zf-FCS PF06467.14 CBK21673.2 - 0.046 13.7 0.3 0.081 12.9 0.3 1.5 1 0 0 1 1 1 0 MYM-type Zinc finger with FCS sequence motif zf-C2HC_2 PF13913.6 CBK21673.2 - 1.4 8.9 4.2 0.51 10.3 1.1 2.0 2 0 0 2 2 2 0 zinc-finger of a C2HC-type Peptidase_C1 PF00112.23 CBK21674.2 - 1e-101 339.6 26.4 2e-57 194.8 6.2 2.1 2 0 0 2 2 2 2 Papain family cysteine protease Peptidase_C1_2 PF03051.15 CBK21674.2 - 0.0052 15.6 12.2 0.036 12.8 1.5 3.2 3 0 0 3 3 3 2 Peptidase C1-like family SPATA48 PF15073.6 CBK21674.2 - 0.16 12.3 0.0 5.7 7.3 0.0 2.3 2 0 0 2 2 2 0 Spermatogenesis-associated protein 48 Ketoacyl-synt_C PF02801.22 CBK21675.2 - 2.5e-28 98.5 0.1 4.5e-28 97.6 0.1 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain ketoacyl-synt PF00109.26 CBK21675.2 - 5.3e-19 68.8 1.1 9.2e-19 68.0 0.2 1.8 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Thiolase_N PF00108.23 CBK21675.2 - 0.00032 20.1 0.1 0.0021 17.5 0.0 2.0 2 0 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 CBK21675.2 - 0.067 12.8 0.2 0.13 11.9 0.2 1.4 1 0 0 1 1 1 0 Thiolase, C-terminal domain Alg14 PF08660.11 CBK21676.2 - 4.6e-54 183.0 0.4 7e-54 182.4 0.4 1.3 1 1 0 1 1 1 1 Oligosaccharide biosynthesis protein Alg14 like RPN13_C PF16550.5 CBK21677.2 - 3.6e-11 43.2 0.0 5.5e-11 42.6 0.0 1.3 1 0 0 1 1 1 1 UCH-binding domain Proteasom_Rpn13 PF04683.13 CBK21677.2 - 0.00026 21.5 0.0 0.00046 20.7 0.0 1.4 1 0 0 1 1 1 1 Proteasome complex subunit Rpn13 ubiquitin receptor Linker_histone PF00538.19 CBK21678.2 - 5.8e-12 45.8 0.1 5.8e-12 45.8 0.1 2.7 1 1 1 2 2 2 1 linker histone H1 and H5 family DUF4708 PF15813.5 CBK21678.2 - 0.011 14.9 1.7 0.016 14.4 1.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4708) BSP_II PF05432.11 CBK21678.2 - 1 9.0 38.9 1.4 8.6 38.9 1.2 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) Hid1 PF12722.7 CBK21678.2 - 3 5.9 35.8 3.8 5.5 35.8 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Ntox16 PF15523.6 CBK21679.2 - 0.13 12.5 0.0 0.3 11.4 0.0 1.6 1 0 0 1 1 1 0 Novel toxin 16 Amidinotransf PF02274.17 CBK21679.2 - 0.59 9.2 3.5 21 4.0 3.6 2.2 2 0 0 2 2 2 0 Amidinotransferase Sugar_transport PF06800.12 CBK21680.2 - 7e-09 35.4 0.7 1.9e-06 27.4 0.1 2.2 2 0 0 2 2 2 2 Sugar transport protein Ureide_permease PF07168.11 CBK21680.2 - 4.3e-08 32.3 6.4 1.6e-06 27.1 1.5 2.1 2 0 0 2 2 2 2 Ureide permease TMEM144 PF07857.12 CBK21680.2 - 2.7e-07 29.9 1.1 4.9e-07 29.0 0.1 1.9 2 0 0 2 2 2 1 Transmembrane family, TMEM144 of transporters Ank_2 PF12796.7 CBK21681.2 - 1e-23 83.7 0.0 2.9e-07 31.0 0.0 6.4 4 1 2 6 6 6 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CBK21681.2 - 1.9e-18 66.6 6.5 0.0038 17.8 0.0 7.0 6 1 0 6 6 6 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 CBK21681.2 - 2.9e-13 49.8 7.9 0.13 12.7 0.1 7.0 5 2 0 6 6 6 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 CBK21681.2 - 1.7e-12 46.3 10.9 0.23 12.1 0.0 8.9 9 0 0 9 9 9 3 Ankyrin repeat Ank PF00023.30 CBK21681.2 - 5e-12 45.7 15.0 0.24 11.9 0.0 8.8 9 0 0 9 9 9 3 Ankyrin repeat FYVE PF01363.21 CBK21681.2 - 1.5e-09 37.9 13.2 4.7e-09 36.2 13.2 1.8 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.16 CBK21681.2 - 0.00012 22.3 9.1 0.00025 21.2 9.1 1.5 1 0 0 1 1 1 1 FYVE-type zinc finger Mito_carr PF00153.27 CBK21682.2 - 1.4e-10 41.0 0.1 1.4e-10 41.0 0.1 1.0 1 0 0 1 1 1 1 Mitochondrial carrier protein LRR_4 PF12799.7 CBK21683.2 - 0.0065 16.9 2.3 0.91 10.0 0.6 3.6 2 2 1 3 3 3 1 Leucine Rich repeats (2 copies) FTH PF01827.27 CBK21683.2 - 0.078 12.8 0.8 14 5.4 0.1 3.0 2 1 1 3 3 3 0 FTH domain LRR_8 PF13855.6 CBK21683.2 - 0.19 11.5 1.4 29 4.5 0.0 3.2 2 1 1 3 3 3 0 Leucine rich repeat RNase_PH PF01138.21 CBK21684.2 - 7.4e-13 49.1 0.1 1.9e-12 47.8 0.0 1.7 2 0 0 2 2 2 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 CBK21684.2 - 5e-07 29.6 0.0 9.7e-07 28.7 0.0 1.5 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 UTP25 PF06862.12 CBK21685.2 - 5.1e-90 302.5 0.0 9.9e-90 301.6 0.0 1.4 1 1 0 1 1 1 1 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 CLASP_N PF12348.8 CBK21686.2 - 8.3e-06 25.5 1.4 1.4e-05 24.8 1.4 1.4 1 0 0 1 1 1 1 CLASP N terminal CAP_GLY PF01302.25 CBK21686.2 - 0.0027 17.7 0.0 0.0048 16.9 0.0 1.4 1 0 0 1 1 1 1 CAP-Gly domain DHHC PF01529.20 CBK21687.2 - 3.1e-23 82.4 11.5 3.5e-23 82.2 11.5 1.2 1 0 0 1 1 1 1 DHHC palmitoyltransferase WD40 PF00400.32 CBK21690.2 - 5.4e-42 141.0 10.9 7.7e-08 32.9 0.8 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBK21690.2 - 1.2e-09 38.3 0.0 3.6 8.0 0.0 5.5 1 1 4 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 CBK21690.2 - 3.9e-09 35.9 0.0 0.036 13.0 0.0 3.7 2 2 2 4 4 4 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Frtz PF11768.8 CBK21690.2 - 0.0045 15.4 0.0 0.027 12.8 0.0 2.2 3 0 0 3 3 3 1 WD repeat-containing and planar cell polarity effector protein Fritz Nbas_N PF15492.6 CBK21690.2 - 0.0092 15.3 0.0 2 7.6 0.0 3.4 3 1 1 4 4 4 1 Neuroblastoma-amplified sequence, N terminal WD40_like PF17005.5 CBK21690.2 - 0.012 14.9 0.0 0.14 11.4 0.0 2.3 2 1 1 3 3 3 0 WD40-like domain Cytochrom_D1 PF02239.16 CBK21690.2 - 0.03 12.8 0.0 24 3.3 0.0 3.1 2 1 2 4 4 4 0 Cytochrome D1 heme domain APG6 PF04111.12 CBK21691.2 - 8.2e-11 42.2 0.0 9.5e-11 42.0 0.0 1.1 1 0 0 1 1 1 1 Apg6 BARA domain DUF4427 PF14468.6 CBK21692.2 - 0.044 13.9 0.0 0.045 13.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4427) MFS_1 PF07690.16 CBK21693.2 - 4.6e-31 108.0 0.9 4.7e-31 108.0 0.9 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 CBK21693.2 - 8.7e-18 64.4 2.5 1e-17 64.1 2.5 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter EMC3_TMCO1 PF01956.16 CBK21693.2 - 0.0014 18.4 0.1 0.0027 17.4 0.1 1.5 1 0 0 1 1 1 1 Integral membrane protein EMC3/TMCO1-like TRI12 PF06609.13 CBK21693.2 - 0.002 16.7 1.1 0.0023 16.4 1.1 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1_like PF12832.7 CBK21693.2 - 0.0078 15.1 1.3 0.029 13.2 1.3 1.8 1 1 0 1 1 1 1 MFS_1 like family DUF2232 PF09991.9 CBK21693.2 - 0.011 14.9 0.1 0.011 14.9 0.1 2.0 2 0 0 2 2 2 0 Predicted membrane protein (DUF2232) Galanin PF01296.18 CBK21693.2 - 0.12 12.4 0.2 0.22 11.5 0.2 1.4 1 0 0 1 1 1 0 Galanin Peptidase_A24 PF01478.18 CBK21693.2 - 1.3 9.5 8.1 2.1 8.8 5.8 2.3 2 1 1 3 3 3 0 Type IV leader peptidase family He_PIG PF05345.12 CBK21694.2 - 0.0011 19.1 2.9 0.0047 17.1 2.9 2.2 1 1 0 1 1 1 1 Putative Ig domain Oxidored_q2 PF00420.24 CBK21694.2 - 0.011 15.3 0.2 0.021 14.4 0.2 1.4 1 0 0 1 1 1 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L TMEM154 PF15102.6 CBK21694.2 - 0.038 13.9 0.2 0.085 12.8 0.2 1.5 1 0 0 1 1 1 0 TMEM154 protein family RIFIN PF02009.16 CBK21694.2 - 0.061 13.2 0.2 0.097 12.6 0.2 1.3 1 0 0 1 1 1 0 Rifin ASFV_J13L PF05568.11 CBK21694.2 - 0.076 12.8 0.3 0.13 12.0 0.3 1.3 1 0 0 1 1 1 0 African swine fever virus J13L protein ECSCR PF15820.5 CBK21694.2 - 0.11 12.3 1.6 0.35 10.7 1.6 1.8 1 0 0 1 1 1 0 Endothelial cell-specific chemotaxis regulator Sushi PF00084.20 CBK21694.2 - 0.16 12.6 7.9 0.12 13.0 1.3 3.1 3 0 0 3 3 3 0 Sushi repeat (SCR repeat) He_PIG PF05345.12 CBK21695.2 - 3e-22 78.6 61.3 3.6e-07 30.3 2.2 8.8 8 1 0 8 8 8 5 Putative Ig domain PA14 PF07691.12 CBK21695.2 - 3e-17 62.8 0.7 7.1e-10 38.9 0.1 3.6 3 0 0 3 3 3 2 PA14 domain F5_F8_type_C PF00754.25 CBK21695.2 - 0.0093 16.1 2.5 0.036 14.2 2.5 2.1 1 0 0 1 1 1 1 F5/8 type C domain DUF5385 PF17359.2 CBK21695.2 - 0.04 13.5 0.6 0.078 12.5 0.6 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5385) Pilin_N PF07790.11 CBK21695.2 - 0.057 14.3 0.0 0.25 12.3 0.0 2.1 1 0 0 1 1 1 0 Archaeal Type IV pilin, N-terminal DUF3180 PF11377.8 CBK21695.2 - 0.064 13.4 0.0 0.14 12.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3180) HRM PF02793.22 CBK21695.2 - 0.071 13.4 0.7 0.19 12.1 0.7 1.7 1 0 0 1 1 1 0 Hormone receptor domain YbaB_DNA_bd PF02575.16 CBK21695.2 - 0.087 13.1 0.0 0.83 9.9 0.0 2.3 2 0 0 2 2 2 0 YbaB/EbfC DNA-binding family FeoB_associated PF12669.7 CBK21695.2 - 0.11 12.9 2.5 0.24 11.8 2.5 1.5 1 0 0 1 1 1 0 FeoB-associated Cys-rich membrane protein Collectrin PF16959.5 CBK21695.2 - 0.65 9.8 5.4 0.13 12.1 1.7 1.6 2 0 0 2 2 2 0 Renal amino acid transporter ECSCR PF15820.5 CBK21695.2 - 3 7.7 4.2 2 8.3 0.2 2.7 3 0 0 3 3 3 0 Endothelial cell-specific chemotaxis regulator CNOT11 PF10155.9 CBK21696.2 - 9.4e-10 38.7 3.1 9.4e-10 38.7 3.1 1.7 2 0 0 2 2 2 1 CCR4-NOT transcription complex subunit 11 Abhydrolase_3 PF07859.13 CBK21697.2 - 1e-35 123.5 0.0 1.3e-35 123.2 0.0 1.0 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 CBK21697.2 - 1.9e-05 24.2 0.0 2.6e-05 23.8 0.0 1.1 1 0 0 1 1 1 1 Prolyl oligopeptidase family Say1_Mug180 PF10340.9 CBK21697.2 - 0.00011 21.3 0.0 0.00013 20.9 0.0 1.1 1 0 0 1 1 1 1 Steryl acetyl hydrolase Hydrolase_4 PF12146.8 CBK21697.2 - 0.0054 16.0 0.0 0.0063 15.8 0.0 1.1 1 0 0 1 1 1 1 Serine aminopeptidase, S33 COesterase PF00135.28 CBK21697.2 - 0.0064 15.4 0.0 0.009 14.9 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_1 PF00561.20 CBK21697.2 - 0.009 15.7 0.0 0.011 15.4 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Fib_alpha PF08702.10 CBK21698.2 - 0.015 15.5 1.4 0.015 15.5 1.4 2.3 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family APG6_N PF17675.1 CBK21698.2 - 0.018 15.6 22.3 0.021 15.4 7.1 3.5 1 1 2 3 3 3 0 Apg6 coiled-coil region Mito_fiss_reg PF05308.11 CBK21698.2 - 0.038 14.1 0.8 0.038 14.1 0.8 1.9 2 1 1 3 3 3 0 Mitochondrial fission regulator bZIP_2 PF07716.15 CBK21698.2 - 0.04 14.0 6.7 0.64 10.2 0.2 3.0 1 1 1 2 2 2 0 Basic region leucine zipper GreA_GreB_N PF03449.15 CBK21698.2 - 0.051 13.7 3.8 8.5 6.6 1.1 3.2 2 1 0 2 2 2 0 Transcription elongation factor, N-terminal BLOC1_2 PF10046.9 CBK21698.2 - 0.075 13.3 1.5 0.34 11.2 0.7 2.4 1 1 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 M PF02370.16 CBK21698.2 - 0.18 12.5 2.9 1.9 9.3 0.4 3.3 2 0 0 2 2 2 0 M protein repeat Med9 PF07544.13 CBK21698.2 - 0.43 10.7 4.8 1.6 8.9 2.1 2.8 1 1 1 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 UPF0449 PF15136.6 CBK21698.2 - 0.84 10.1 5.2 0.39 11.2 1.3 2.5 3 0 0 3 3 3 0 Uncharacterised protein family UPF0449 FlaC_arch PF05377.11 CBK21698.2 - 0.97 9.9 5.2 3.3 8.2 0.4 3.8 2 2 1 3 3 3 0 Flagella accessory protein C (FlaC) GAS PF13851.6 CBK21698.2 - 1.2 8.4 9.3 0.048 13.0 1.5 2.5 2 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding DUF1664 PF07889.12 CBK21698.2 - 3 7.9 6.9 1.3 9.0 0.5 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) Tropomyosin_1 PF12718.7 CBK21698.2 - 4.1 7.6 13.5 0.19 11.9 5.4 2.4 2 2 0 2 2 2 0 Tropomyosin like ABC_tran_CTD PF16326.5 CBK21698.2 - 4.6 7.6 11.8 4.6 7.6 3.7 4.0 2 2 2 4 4 4 0 ABC transporter C-terminal domain DivIC PF04977.15 CBK21698.2 - 5.5 6.8 6.9 9 6.1 0.6 3.0 1 1 1 2 2 2 0 Septum formation initiator Seryl_tRNA_N PF02403.22 CBK21698.2 - 5.9 7.2 9.7 0.42 10.9 2.3 2.8 2 2 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DUF4407 PF14362.6 CBK21698.2 - 8 5.7 11.4 2.9 7.2 7.9 2.0 2 1 0 2 2 2 0 Domain of unknown function (DUF4407) DUF4200 PF13863.6 CBK21698.2 - 9.2 6.7 10.9 0.12 12.8 2.4 2.3 3 0 0 3 3 2 0 Domain of unknown function (DUF4200) DUF641 PF04859.12 CBK21698.2 - 9.6 6.6 10.5 19 5.6 4.7 3.1 2 1 0 2 2 2 0 Plant protein of unknown function (DUF641) Formyl_trans_N PF00551.19 CBK21699.2 - 1.6e-15 57.3 0.1 2.5e-15 56.7 0.1 1.4 1 0 0 1 1 1 1 Formyl transferase Formyl_trans_C PF02911.18 CBK21699.2 - 1e-10 41.7 0.0 2.5e-10 40.5 0.0 1.6 2 0 0 2 2 2 1 Formyl transferase, C-terminal domain Collar PF07484.12 CBK21699.2 - 0.15 12.1 0.0 0.38 10.8 0.0 1.7 1 0 0 1 1 1 0 Phage Tail Collar Domain RIO1 PF01163.22 CBK21700.2 - 3.6e-73 245.2 1.6 5.7e-73 244.5 0.0 2.0 2 0 0 2 2 2 1 RIO1 family APH PF01636.23 CBK21700.2 - 0.0023 17.9 0.1 1.4 8.8 0.0 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 CBK21700.2 - 0.17 10.6 0.1 0.17 10.6 0.1 2.2 2 0 0 2 2 2 0 Fungal protein kinase DUF3347 PF11827.8 CBK21700.2 - 2.5 8.3 11.5 5.9 7.0 11.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3347) Ribosomal_L3 PF00297.22 CBK21701.2 - 4.9e-175 581.9 9.5 5.6e-175 581.7 9.5 1.0 1 0 0 1 1 1 1 Ribosomal protein L3 PPR PF01535.20 CBK21702.2 - 0.00051 20.1 0.2 0.016 15.4 0.0 3.3 3 0 0 3 3 3 1 PPR repeat PPR_2 PF13041.6 CBK21702.2 - 0.011 15.9 0.2 0.35 11.1 0.0 3.1 4 0 0 4 4 4 0 PPR repeat family TPR_2 PF07719.17 CBK21702.2 - 0.012 15.7 1.0 0.056 13.6 1.0 2.2 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_1 PF00515.28 CBK21702.2 - 0.014 15.2 1.4 0.047 13.5 1.4 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat SE PF08491.10 CBK21702.2 - 0.033 13.2 0.4 2.1 7.3 0.0 2.7 3 0 0 3 3 3 0 Squalene epoxidase TPR_19 PF14559.6 CBK21702.2 - 0.072 13.6 0.2 11 6.6 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat RhoGEF PF00621.20 CBK21703.2 - 1.2e-49 169.1 0.2 1.4e-49 168.8 0.2 1.0 1 0 0 1 1 1 1 RhoGEF domain Peptidase_S31 PF05578.12 CBK21703.2 - 0.026 14.1 0.0 0.041 13.4 0.0 1.3 1 0 0 1 1 1 0 Pestivirus NS3 polyprotein peptidase S31 BET PF17035.5 CBK21704.2 - 1.5e-18 66.7 0.7 1.5e-18 66.7 0.7 2.0 2 0 0 2 2 2 1 Bromodomain extra-terminal - transcription regulation Bromodomain PF00439.25 CBK21704.2 - 1e-17 63.9 0.0 2.5e-17 62.7 0.0 1.7 1 0 0 1 1 1 1 Bromodomain Dynamitin PF04912.14 CBK21704.2 - 0.00098 18.6 6.8 0.0017 17.8 6.8 1.3 1 0 0 1 1 1 1 Dynamitin GreA_GreB_N PF03449.15 CBK21704.2 - 0.001 19.1 3.6 0.4 10.8 0.8 2.9 3 0 0 3 3 3 2 Transcription elongation factor, N-terminal AHD PF17793.1 CBK21704.2 - 0.0067 16.2 1.1 0.082 12.7 0.0 2.5 2 0 0 2 2 2 1 ANC1 homology domain (AHD) Auxin_canalis PF05703.11 CBK21704.2 - 0.032 14.2 1.3 0.04 13.8 1.3 1.2 1 0 0 1 1 1 0 Auxin canalisation LRS4 PF10422.9 CBK21704.2 - 0.99 8.9 7.7 0.27 10.8 4.4 1.5 1 1 0 1 1 1 0 Monopolin complex subunit LRS4 HAT_KAT11 PF08214.11 CBK21705.2 - 4.2e-13 49.3 0.1 1.6e-12 47.4 0.0 1.8 1 1 1 2 2 2 1 Histone acetylation protein PHD PF00628.29 CBK21705.2 - 0.00023 21.0 1.6 0.00023 21.0 1.6 2.1 2 0 0 2 2 2 1 PHD-finger zf-TAZ PF02135.16 CBK21706.2 - 1.1e-07 32.2 15.4 1.3e-07 32.0 15.4 1.0 1 0 0 1 1 1 1 TAZ zinc finger VWC PF00093.18 CBK21706.2 - 0.59 10.5 14.8 8.5 6.8 9.0 2.1 1 1 1 2 2 2 0 von Willebrand factor type C domain Adaptin_N PF01602.20 CBK21707.2 - 5.6e-74 249.6 1.3 7e-74 249.2 1.3 1.1 1 0 0 1 1 1 1 Adaptin N terminal region COP-gamma_platf PF08752.10 CBK21707.2 - 3.4e-34 118.1 0.0 7.4e-34 117.0 0.0 1.5 1 0 0 1 1 1 1 Coatomer gamma subunit appendage platform subdomain Coatomer_g_Cpla PF16381.5 CBK21707.2 - 3e-30 104.7 0.0 1.6e-29 102.3 0.0 2.1 2 0 0 2 2 2 1 Coatomer subunit gamma-1 C-terminal appendage platform Cnd1 PF12717.7 CBK21707.2 - 2e-07 31.2 4.8 0.052 13.6 0.3 4.3 2 1 2 4 4 4 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 CBK21707.2 - 1.6e-06 28.4 12.6 0.00021 21.6 2.2 5.3 3 2 3 6 6 6 3 HEAT repeats HEAT PF02985.22 CBK21707.2 - 0.0028 17.8 16.3 1.7 9.1 0.1 6.1 5 0 0 5 5 5 2 HEAT repeat AbiJ_NTD5 PF18865.1 CBK21707.2 - 0.012 15.4 0.3 0.096 12.5 0.1 2.6 2 0 0 2 2 2 0 AbiJ N-terminal domain 5 Arm PF00514.23 CBK21707.2 - 0.22 11.6 1.3 4 7.6 0.0 3.7 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat HEAT_PBS PF03130.16 CBK21707.2 - 0.59 11.0 5.4 3.9 8.4 2.0 3.9 2 1 1 3 3 3 0 PBS lyase HEAT-like repeat HEAT_EZ PF13513.6 CBK21707.2 - 1.6 9.3 25.5 0.047 14.2 4.5 6.1 7 1 1 8 8 8 0 HEAT-like repeat Peptidase_C1 PF00112.23 CBK21708.2 - 9.3e-70 235.1 4.6 1.2e-69 234.7 4.6 1.1 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 CBK21708.2 - 1.1e-16 60.9 0.2 1.8e-16 60.3 0.2 1.3 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.15 CBK21708.2 - 1.3e-07 30.8 0.5 5.1e-05 22.2 0.1 2.2 2 0 0 2 2 2 2 Peptidase C1-like family Propeptide_C1 PF08127.13 CBK21708.2 - 0.019 14.8 0.0 0.042 13.7 0.0 1.5 1 0 0 1 1 1 0 Peptidase family C1 propeptide ESAG1 PF03238.13 CBK21708.2 - 0.045 13.2 0.1 0.072 12.5 0.1 1.2 1 0 0 1 1 1 0 ESAG protein P33MONOX PF15302.6 CBK21708.2 - 0.24 11.1 0.0 0.33 10.6 0.0 1.2 1 0 0 1 1 1 0 P33 mono-oxygenase PIF1 PF05970.14 CBK21709.2 - 7e-35 120.9 0.1 2.8e-21 76.1 0.0 2.3 1 1 1 2 2 2 2 PIF1-like helicase AAA_30 PF13604.6 CBK21709.2 - 1.1e-08 35.0 0.0 2e-08 34.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain Glyoxalase_4 PF13669.6 CBK21710.2 - 4.5e-18 65.5 0.0 6.5e-18 65.0 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase PF00903.25 CBK21710.2 - 0.15 12.3 0.0 0.21 11.8 0.0 1.4 1 0 0 1 1 1 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.6 CBK21710.2 - 0.23 11.6 0.0 0.4 10.8 0.0 1.4 1 0 0 1 1 1 0 Glyoxalase-like domain DHHC PF01529.20 CBK21711.2 - 1.7e-29 102.6 18.0 1.7e-29 102.6 18.0 1.6 2 0 0 2 2 2 1 DHHC palmitoyltransferase Pex24p PF06398.11 CBK21711.2 - 1.8 7.5 10.9 9 5.2 10.4 2.0 1 1 0 1 1 1 0 Integral peroxisomal membrane peroxin ABC_tran PF00005.27 CBK21712.2 - 2.6e-47 160.8 0.7 7.3e-22 78.4 0.0 3.6 3 0 0 3 3 3 2 ABC transporter AAA_21 PF13304.6 CBK21712.2 - 4.4e-15 56.3 15.3 3.8e-05 23.7 0.1 5.1 3 2 2 5 5 5 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 CBK21712.2 - 3.7e-11 42.9 0.6 0.01 15.3 0.1 4.0 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 CBK21712.2 - 1.2e-06 28.2 0.0 0.049 13.4 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain ABC_tran_Xtn PF12848.7 CBK21712.2 - 4.9e-06 26.5 6.7 4.9e-06 26.5 6.7 3.8 3 1 1 4 4 1 1 ABC transporter RsgA_GTPase PF03193.16 CBK21712.2 - 2.7e-05 24.1 0.0 0.057 13.3 0.0 2.8 2 0 0 2 2 2 2 RsgA GTPase AAA PF00004.29 CBK21712.2 - 4.3e-05 24.0 0.0 1 9.8 0.1 3.4 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 CBK21712.2 - 0.00035 20.3 0.0 0.59 9.8 0.0 2.9 2 0 0 2 2 2 2 AAA domain NACHT PF05729.12 CBK21712.2 - 0.00061 19.8 0.2 1.1 9.1 0.0 2.6 2 0 0 2 2 2 2 NACHT domain AAA_22 PF13401.6 CBK21712.2 - 0.00063 20.0 0.0 2 8.7 0.0 3.1 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 CBK21712.2 - 0.00095 19.6 6.7 0.32 11.4 0.0 3.6 4 0 0 4 4 4 2 AAA ATPase domain RNA_helicase PF00910.22 CBK21712.2 - 0.00099 19.5 0.0 1.7 9.1 0.0 2.7 2 0 0 2 2 2 2 RNA helicase AAA_14 PF13173.6 CBK21712.2 - 0.0061 16.6 4.9 0.56 10.3 0.6 3.8 4 1 0 4 4 2 1 AAA domain NTPase_1 PF03266.15 CBK21712.2 - 0.0064 16.4 0.3 2.1 8.3 0.0 3.1 3 0 0 3 3 3 1 NTPase NB-ARC PF00931.22 CBK21712.2 - 0.0073 15.5 0.0 1.4 8.1 0.0 2.7 2 0 0 2 2 2 1 NB-ARC domain MMR_HSR1 PF01926.23 CBK21712.2 - 0.0078 16.3 0.1 5.5 7.1 0.1 3.3 3 0 0 3 3 3 1 50S ribosome-binding GTPase AAA_23 PF13476.6 CBK21712.2 - 0.012 16.2 0.0 0.22 12.0 0.0 5.3 5 0 0 5 5 5 0 AAA domain AAA_33 PF13671.6 CBK21712.2 - 0.035 14.3 2.4 4.9 7.3 0.0 3.3 4 0 0 4 4 3 0 AAA domain AAA_5 PF07728.14 CBK21712.2 - 0.054 13.5 0.1 10 6.1 0.0 2.8 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_28 PF13521.6 CBK21712.2 - 1.9 8.7 10.5 3.2 8.0 0.0 3.7 4 1 0 4 4 4 0 AAA domain DUF262 PF03235.14 CBK21712.2 - 5.8 7.0 17.7 1.7 8.8 0.7 3.3 3 0 0 3 3 3 0 Protein of unknown function DUF262 Aa_trans PF01490.18 CBK21714.2 - 4.4e-47 160.7 33.5 5.5e-47 160.4 33.5 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein PDR_CDR PF06422.12 CBK21714.2 - 0.94 9.4 0.0 0.94 9.4 0.0 3.7 3 1 0 3 3 3 0 CDR ABC transporter DUF202 PF02656.15 CBK21714.2 - 7.7 7.0 15.4 3.9 8.0 0.4 4.1 3 1 0 3 3 3 0 Domain of unknown function (DUF202) UPF0020 PF01170.18 CBK21715.2 - 2.1e-06 27.6 0.0 3e-05 23.8 0.0 2.3 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 N6_N4_Mtase PF01555.18 CBK21715.2 - 0.00015 21.5 0.0 0.002 17.9 0.0 2.4 2 1 0 2 2 2 1 DNA methylase Cons_hypoth95 PF03602.15 CBK21715.2 - 0.0064 16.2 0.0 0.014 15.0 0.0 1.5 1 0 0 1 1 1 1 Conserved hypothetical protein 95 EGF PF00008.27 CBK21716.2 - 0.36 11.2 52.4 0.43 10.9 9.8 5.4 5 0 0 5 5 5 0 EGF-like domain Brix PF04427.18 CBK21717.2 - 9.9e-33 113.9 0.5 1.5e-32 113.3 0.5 1.3 1 0 0 1 1 1 1 Brix domain zf-FLZ PF04570.14 CBK21718.2 - 0.27 10.7 3.2 1.1 8.8 1.1 2.5 3 0 0 3 3 3 0 zinc-finger of the FCS-type, C2-C2 UQ_con PF00179.26 CBK21720.2 - 1e-38 132.2 0.0 1.3e-38 131.8 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 CBK21720.2 - 0.0029 17.3 0.0 0.0044 16.7 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 CBK21720.2 - 0.056 13.7 0.7 0.096 13.0 0.7 1.8 1 1 0 1 1 1 0 RWD domain UCH PF00443.29 CBK21721.2 - 2e-08 34.1 0.0 2.2e-08 33.9 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH PF00443.29 CBK21722.2 - 2.1e-20 73.3 0.0 3e-20 72.8 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 CBK21722.2 - 0.0014 18.3 0.0 0.0028 17.3 0.0 1.5 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase RCC1 PF00415.18 CBK21723.2 - 5.8e-42 142.1 10.1 5e-12 46.2 0.0 5.3 5 0 0 5 5 5 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 CBK21723.2 - 9.6e-23 79.4 27.2 2e-07 30.7 0.2 5.5 5 0 0 5 5 5 5 Regulator of chromosome condensation (RCC1) repeat RRM_1 PF00076.22 CBK21724.2 - 2.6e-06 27.2 0.1 3.3e-06 26.8 0.1 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Myb_DNA-bind_6 PF13921.6 CBK21725.2 - 0.063 13.5 0.9 0.081 13.2 0.9 1.1 1 0 0 1 1 1 0 Myb-like DNA-binding domain SDH_alpha PF03313.15 CBK21726.2 - 2.1e-77 260.3 5.1 2.6e-77 260.0 5.1 1.1 1 0 0 1 1 1 1 Serine dehydratase alpha chain SDH_beta PF03315.15 CBK21726.2 - 8.9e-28 97.6 2.3 3.5e-17 63.2 0.0 2.7 2 1 1 3 3 3 2 Serine dehydratase beta chain MmgE_PrpD PF03972.14 CBK21726.2 - 0.0091 14.6 3.0 0.012 14.2 3.0 1.1 1 0 0 1 1 1 1 MmgE/PrpD family TCR PF03638.15 CBK21727.2 - 2e-23 82.4 54.7 1e-11 44.9 22.6 2.4 2 0 0 2 2 2 2 Tesmin/TSO1-like CXC domain, cysteine-rich domain K_channel_TID PF07941.11 CBK21727.2 - 2.8 8.4 9.2 6.7 7.2 6.2 2.5 2 0 0 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain MSL2-CXC PF16682.5 CBK21727.2 - 3.6 7.8 50.4 7.8 6.7 20.5 2.8 2 1 0 2 2 2 0 CXC domain of E3 ubiquitin-protein ligase MSL2 MRG PF05712.13 CBK21729.2 - 1.7e-18 66.6 0.7 2.4e-18 66.2 0.7 1.2 1 0 0 1 1 1 1 MRG DUF5355 PF17306.2 CBK21729.2 - 0.0035 16.4 0.1 0.0043 16.1 0.1 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF5355) AA_permease PF00324.21 CBK21730.2 - 1.4e-13 50.3 10.7 1.5e-13 50.2 10.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 CBK21731.2 - 2.6e-45 154.9 14.4 3.4e-45 154.6 14.4 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 CBK21731.2 - 7.8e-17 61.2 21.4 7.8e-17 61.2 21.4 1.9 2 0 0 2 2 2 1 Amino acid permease SLC12 PF03522.15 CBK21731.2 - 5.3e-08 32.3 0.0 7.4e-08 31.8 0.0 1.1 1 0 0 1 1 1 1 Solute carrier family 12 Collagen PF01391.18 CBK21732.2 - 2e-31 107.5 106.7 6e-10 38.7 27.0 4.2 1 1 3 4 4 4 4 Collagen triple helix repeat (20 copies) Actin PF00022.19 CBK21733.2 - 5.9e-94 315.0 0.0 2.6e-93 312.8 0.0 1.7 1 1 0 1 1 1 1 Actin DAP3 PF10236.9 CBK21734.2 - 3.4e-22 79.0 0.0 6.7e-22 78.1 0.0 1.4 1 1 0 1 1 1 1 Mitochondrial ribosomal death-associated protein 3 AAA_16 PF13191.6 CBK21734.2 - 0.00028 21.3 0.0 0.0012 19.3 0.0 2.1 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 CBK21734.2 - 0.0031 17.8 0.1 0.035 14.4 0.1 2.3 1 1 0 1 1 1 1 AAA domain ATPase_2 PF01637.18 CBK21734.2 - 0.041 13.8 0.0 0.18 11.7 0.0 2.0 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_14 PF13173.6 CBK21734.2 - 0.06 13.4 0.0 0.19 11.7 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 CBK21734.2 - 0.06 13.3 0.0 1.6 8.8 0.0 2.5 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_23 PF13476.6 CBK21734.2 - 0.11 13.0 0.1 0.39 11.2 0.0 1.9 1 1 1 2 2 2 0 AAA domain NDUF_B12 PF08122.12 CBK21735.2 - 1.9e-07 31.0 0.3 2.5e-07 30.6 0.3 1.2 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B12 subunit family Nop25 PF09805.9 CBK21736.2 - 1.5e-05 25.5 27.6 1.5e-05 25.5 27.6 2.3 1 1 0 1 1 1 1 Nucleolar protein 12 (25kDa) Mem_trans PF03547.18 CBK21736.2 - 0.41 9.0 3.9 0.56 8.6 3.9 1.1 1 0 0 1 1 1 0 Membrane transport protein DUF313 PF03754.13 CBK21736.2 - 0.58 10.4 5.9 7.5 6.8 2.7 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF313) Myc_N PF01056.18 CBK21737.2 - 0.012 15.5 1.8 0.017 15.1 1.8 1.1 1 0 0 1 1 1 0 Myc amino-terminal region Metallophos PF00149.28 CBK21738.2 - 8e-37 127.7 0.2 1.1e-36 127.3 0.2 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Glyco_hydro_65N PF03636.15 CBK21738.2 - 0.033 13.8 0.0 0.045 13.4 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 65, N-terminal domain RPW8 PF05659.11 CBK21738.2 - 0.096 12.4 0.4 0.17 11.6 0.4 1.3 1 0 0 1 1 1 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 GBP PF02263.19 CBK21739.2 - 2.7e-44 151.4 0.1 1.7e-35 122.6 0.0 2.1 2 0 0 2 2 2 2 Guanylate-binding protein, N-terminal domain AAA_16 PF13191.6 CBK21739.2 - 0.055 13.9 0.0 0.13 12.6 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain Ribosomal_S14 PF00253.21 CBK21740.2 - 7e-13 48.1 5.3 8e-13 47.9 5.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e ATP-grasp_5 PF13549.6 CBK21741.2 - 5.4e-53 179.7 0.0 7.8e-53 179.2 0.0 1.2 1 0 0 1 1 1 1 ATP-grasp domain Succ_CoA_lig PF13607.6 CBK21741.2 - 1.2e-40 138.5 0.0 1.5e-39 135.0 0.0 2.7 3 0 0 3 3 3 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.6 CBK21741.2 - 1.9e-18 67.0 0.0 5.9e-18 65.5 0.0 1.9 2 0 0 2 2 2 1 CoA binding domain CoA_binding PF02629.19 CBK21741.2 - 2.7e-05 24.8 0.0 6.5e-05 23.5 0.0 1.7 1 0 0 1 1 1 1 CoA binding domain Abhydrolase_6 PF12697.7 CBK21742.2 - 2.6e-21 77.3 0.0 3.2e-21 77.0 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.20 CBK21742.2 - 1.7e-07 31.6 0.0 4.4e-07 30.2 0.0 1.7 1 0 0 1 1 1 1 Thioesterase domain Hydrolase_4 PF12146.8 CBK21742.2 - 4.7e-06 26.1 0.0 7.8e-06 25.3 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Chlorophyllase PF07224.11 CBK21742.2 - 8.5e-05 21.7 0.0 0.00012 21.2 0.0 1.1 1 0 0 1 1 1 1 Chlorophyllase PGAP1 PF07819.13 CBK21742.2 - 0.00092 19.0 0.1 0.002 17.9 0.1 1.5 1 1 0 1 1 1 1 PGAP1-like protein Abhydrolase_1 PF00561.20 CBK21742.2 - 0.0013 18.4 0.2 0.012 15.3 0.0 2.4 2 1 0 2 2 2 1 alpha/beta hydrolase fold DUF2974 PF11187.8 CBK21742.2 - 0.0083 15.7 0.2 0.054 13.0 0.0 2.2 3 0 0 3 3 3 1 Protein of unknown function (DUF2974) LIDHydrolase PF10230.9 CBK21742.2 - 0.012 15.1 0.0 0.019 14.5 0.0 1.2 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase Chlorophyllase2 PF12740.7 CBK21742.2 - 0.024 13.6 0.0 0.033 13.1 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme Lipase_3 PF01764.25 CBK21742.2 - 0.025 14.4 0.0 0.05 13.5 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 3) Abhydrolase_3 PF07859.13 CBK21742.2 - 0.076 12.9 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold Ser_hydrolase PF06821.13 CBK21742.2 - 0.16 11.8 0.0 0.3 10.9 0.0 1.4 1 0 0 1 1 1 0 Serine hydrolase PG_binding_1 PF01471.18 CBK21742.2 - 0.18 12.0 0.0 0.38 11.0 0.0 1.5 1 0 0 1 1 1 0 Putative peptidoglycan binding domain PCI PF01399.27 CBK21743.2 - 6.1e-05 23.5 0.4 0.00012 22.5 0.0 1.8 2 1 0 2 2 2 1 PCI domain Coilin_N PF15862.5 CBK21743.2 - 0.00062 19.6 0.0 0.002 17.9 0.0 2.0 1 1 0 1 1 1 1 Coilin N-terminus Suf PF05843.14 CBK21743.2 - 0.85 9.5 15.5 1.1 9.1 15.5 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) TFIIA PF03153.13 CBK21743.2 - 1 9.3 24.1 1.2 9.0 24.1 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit eIF-3_zeta PF05091.12 CBK21743.2 - 4.7 6.1 16.8 4.5 6.1 15.5 1.6 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Presenilin PF01080.17 CBK21743.2 - 5.8 5.6 13.6 7 5.3 13.6 1.1 1 0 0 1 1 1 0 Presenilin Pex14_N PF04695.13 CBK21743.2 - 9 6.9 20.1 13 6.5 20.1 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region eIF-3c_N PF05470.12 CBK21744.2 - 5.1e-15 54.8 0.0 5.7e-15 54.7 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 8 N-terminus eIF-3c_N PF05470.12 CBK21745.2 - 4e-29 101.4 10.7 5.3e-29 101.0 10.7 1.1 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 8 N-terminus tRNA-synt_1e PF01406.19 CBK21745.2 - 0.0043 16.4 0.6 0.008 15.6 0.3 1.5 1 1 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain DUF1796 PF08795.10 CBK21745.2 - 0.0089 16.0 1.2 0.013 15.5 1.2 1.3 1 1 0 1 1 1 1 Putative papain-like cysteine peptidase (DUF1796) AbiJ_NTD5 PF18865.1 CBK21745.2 - 0.01 15.6 0.2 0.13 12.1 0.0 2.3 2 0 0 2 2 2 0 AbiJ N-terminal domain 5 MbeB_N PF04837.12 CBK21745.2 - 0.048 14.0 0.2 0.16 12.3 0.1 1.9 2 0 0 2 2 2 0 MbeB-like, N-term conserved region Spo0A_C PF08769.11 CBK21745.2 - 0.09 12.9 0.4 1.5 9.0 0.0 2.3 2 0 0 2 2 2 0 Sporulation initiation factor Spo0A C terminal HSCB_C PF07743.13 CBK21745.2 - 0.093 13.2 1.5 6.1 7.4 0.2 2.2 2 0 0 2 2 2 0 HSCB C-terminal oligomerisation domain Fib_alpha PF08702.10 CBK21745.2 - 0.12 12.6 0.3 0.12 12.6 0.3 2.0 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family IlvC PF01450.19 CBK21745.2 - 1.3 9.3 5.1 2 8.7 0.8 2.1 1 1 0 2 2 2 0 Acetohydroxy acid isomeroreductase, catalytic domain Spermine_synth PF01564.17 CBK21746.2 - 1.3e-62 210.5 0.0 2.5e-62 209.7 0.0 1.4 1 0 0 1 1 1 1 Spermine/spermidine synthase domain Spermine_synt_N PF17284.2 CBK21746.2 - 1.4e-22 79.3 0.4 2.4e-22 78.6 0.4 1.4 1 0 0 1 1 1 1 Spermidine synthase tetramerisation domain Methyltransf_25 PF13649.6 CBK21746.2 - 7.6e-06 26.5 0.1 2.1e-05 25.1 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_30 PF05430.11 CBK21746.2 - 0.0015 18.4 0.0 0.0025 17.7 0.0 1.3 1 0 0 1 1 1 1 S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_12 PF08242.12 CBK21746.2 - 0.0059 17.3 0.0 0.012 16.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.18 CBK21746.2 - 0.11 11.8 0.2 0.2 10.9 0.2 1.6 1 1 0 1 1 1 0 O-methyltransferase domain MTS PF05175.14 CBK21746.2 - 0.12 11.9 0.0 0.18 11.4 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Aldose_epim PF01263.20 CBK21748.2 - 2.4e-41 142.0 0.1 2.9e-41 141.7 0.1 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase PUA_2 PF14306.6 CBK21748.2 - 0.11 12.2 0.0 0.17 11.6 0.0 1.2 1 0 0 1 1 1 0 PUA-like domain HRM PF02793.22 CBK21749.2 - 3e-17 62.7 32.5 2.5e-09 37.3 4.0 5.3 2 1 3 5 5 5 4 Hormone receptor domain Sushi PF00084.20 CBK21749.2 - 6.7e-06 26.6 30.8 0.0016 19.0 4.8 5.1 5 1 1 6 6 6 3 Sushi repeat (SCR repeat) DUF4493 PF14900.6 CBK21749.2 - 0.11 12.3 0.0 0.17 11.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4493) Pkinase PF00069.25 CBK21750.2 - 1.1e-22 80.6 0.0 1.4e-22 80.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBK21750.2 - 9.3e-10 38.2 0.0 1.1e-09 38.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CBK21750.2 - 2e-05 23.6 0.0 2.5e-05 23.3 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase CybS PF05328.12 CBK21753.2 - 1.6e-09 37.5 0.5 2.2e-09 37.1 0.5 1.2 1 0 0 1 1 1 1 CybS, succinate dehydrogenase cytochrome B small subunit Thioredoxin_7 PF13899.6 CBK21754.2 - 5.4e-09 36.1 0.0 7.6e-09 35.6 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like Thioredox_DsbH PF03190.15 CBK21754.2 - 0.0033 17.4 0.0 0.0043 17.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function, DUF255 AhpC-TSA PF00578.21 CBK21754.2 - 0.0055 16.6 0.4 0.68 9.9 0.1 2.1 1 1 1 2 2 2 2 AhpC/TSA family Neisseria_PilC PF05567.11 CBK21754.2 - 0.019 14.0 0.0 0.021 13.9 0.0 1.2 1 0 0 1 1 1 0 Neisseria PilC beta-propeller domain Thioredoxin_2 PF13098.6 CBK21754.2 - 0.091 13.2 0.0 0.11 13.0 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin-like domain Redoxin PF08534.10 CBK21754.2 - 0.15 11.8 0.1 2.5 7.8 0.0 2.0 1 1 1 2 2 2 0 Redoxin Gin PF10764.9 CBK21754.2 - 0.22 11.5 5.6 0.092 12.7 1.9 2.2 2 0 0 2 2 2 0 Inhibitor of sigma-G Gin zf-met2 PF12907.7 CBK21755.2 - 5.7e-16 58.4 1.1 5.7e-16 58.4 1.1 2.0 2 0 0 2 2 2 1 Zinc-binding zf-BED PF02892.15 CBK21755.2 - 0.0049 16.9 0.0 0.0083 16.1 0.0 1.4 1 0 0 1 1 1 1 BED zinc finger zf-C2H2_12 PF18658.1 CBK21755.2 - 0.0059 16.2 0.1 0.0087 15.6 0.1 1.3 1 0 0 1 1 1 1 Zinc-finger C2H2-type Ribosomal_L5e PF17144.4 CBK21756.2 - 9.9e-77 256.5 1.3 2e-76 255.5 1.3 1.5 1 0 0 1 1 1 1 Ribosomal large subunit proteins 60S L5, and 50S L18 Ribosomal_L18_c PF14204.6 CBK21756.2 - 5e-31 107.5 5.9 1.1e-30 106.4 5.9 1.6 1 0 0 1 1 1 1 Ribosomal L18 C-terminal region EF1G PF00647.19 CBK21757.2 - 9.5e-37 125.3 0.1 1.9e-36 124.3 0.1 1.5 1 0 0 1 1 1 1 Elongation factor 1 gamma, conserved domain GST_C PF00043.25 CBK21757.2 - 1.1e-15 57.6 0.0 1.1e-15 57.6 0.0 2.4 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 CBK21757.2 - 1.7e-11 44.3 0.0 1.7e-11 44.3 0.0 1.8 2 0 0 2 2 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 CBK21757.2 - 2.7e-09 37.3 0.1 9.1e-09 35.6 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 CBK21757.2 - 8.5e-08 32.1 0.0 1.9e-07 31.0 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 CBK21757.2 - 3e-07 30.6 0.0 6.1e-07 29.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 CBK21757.2 - 2.3e-06 27.7 0.0 2.3e-06 27.7 0.0 2.3 3 0 0 3 3 3 1 Glutathione S-transferase, C-terminal domain CPSF100_C PF13299.6 CBK21757.2 - 0.082 13.1 1.4 0.16 12.1 1.4 1.4 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal GST_C_6 PF17171.4 CBK21757.2 - 0.16 11.8 0.0 0.34 10.7 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Tim54 PF11711.8 CBK21757.2 - 1 8.0 6.5 1.5 7.6 6.5 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 NARP1 PF12569.8 CBK21757.2 - 1.8 7.3 6.8 2.8 6.7 6.8 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 TSGP1 PF07771.11 CBK21757.2 - 3 8.0 8.8 6.8 6.9 8.8 1.5 1 0 0 1 1 1 0 Tick salivary peptide group 1 Tyr-DNA_phospho PF06087.12 CBK21758.2 - 8.9e-55 186.3 0.0 1.3e-54 185.7 0.0 1.2 1 0 0 1 1 1 1 Tyrosyl-DNA phosphodiesterase tRNA-synt_1 PF00133.22 CBK21759.2 - 2e-51 175.0 0.1 1.7e-32 112.5 0.1 6.0 2 1 1 3 3 3 3 tRNA synthetases class I (I, L, M and V) tRNA-synt_1_2 PF13603.6 CBK21759.2 - 2.3e-42 144.6 0.0 5.8e-42 143.3 0.0 1.7 1 1 0 1 1 1 1 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1g PF09334.11 CBK21759.2 - 2.4e-23 82.6 0.0 3.7e-18 65.4 0.0 3.5 4 0 0 4 4 4 2 tRNA synthetases class I (M) Anticodon_1 PF08264.13 CBK21759.2 - 1.5e-07 31.5 0.0 3.4e-07 30.3 0.0 1.5 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.19 CBK21759.2 - 0.0091 15.4 0.0 1.7 7.9 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain zf-ribbon_3 PF13248.6 CBK21759.2 - 0.023 14.1 3.7 0.2 11.1 0.3 2.7 2 0 0 2 2 2 0 zinc-ribbon domain Zn-ribbon_8 PF09723.10 CBK21759.2 - 0.61 10.3 2.7 1.7 8.8 0.4 2.5 2 0 0 2 2 2 0 Zinc ribbon domain Adaptin_N PF01602.20 CBK21760.2 - 2.5e-07 29.6 0.0 3.2e-07 29.3 0.0 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Sacchrp_dh_NADP PF03435.18 CBK21760.2 - 0.037 14.3 0.0 0.064 13.5 0.0 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain NIF PF03031.18 CBK21762.2 - 7.5e-47 159.0 0.4 1.1e-46 158.4 0.4 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase GCS PF03074.16 CBK21763.2 - 3.7e-151 503.6 0.2 4.5e-151 503.4 0.2 1.1 1 0 0 1 1 1 1 Glutamate-cysteine ligase Aminotran_1_2 PF00155.21 CBK21765.2 - 3.6e-85 286.3 0.0 4.1e-85 286.1 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Biotin_lipoyl PF00364.22 CBK21766.2 - 2.6e-17 62.4 3.2 3.3e-17 62.1 3.2 1.1 1 0 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 CBK21766.2 - 0.00075 19.3 1.6 0.08 12.8 0.0 2.1 1 1 1 2 2 2 2 Biotin-lipoyl like Snf7 PF03357.21 CBK21767.2 - 1.3e-06 28.1 10.8 1.6e-06 27.8 10.8 1.1 1 0 0 1 1 1 1 Snf7 WD40 PF00400.32 CBK21768.2 - 3.1e-24 84.8 17.2 2.4e-06 28.1 0.1 4.9 5 0 0 5 5 5 4 WD domain, G-beta repeat Sof1 PF04158.14 CBK21768.2 - 9.1e-16 57.9 6.4 1.9e-15 56.9 6.4 1.5 1 0 0 1 1 1 1 Sof1-like domain ANAPC4_WD40 PF12894.7 CBK21768.2 - 3.2e-07 30.5 0.0 0.036 14.4 0.0 4.5 2 1 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Coatomer_WDAD PF04053.14 CBK21768.2 - 0.00095 18.3 0.0 0.0015 17.6 0.0 1.4 1 0 0 1 1 1 1 Coatomer WD associated region Nucleoporin_N PF08801.11 CBK21768.2 - 0.0025 16.6 0.2 1.1 7.9 0.0 2.7 2 1 0 2 2 2 2 Nup133 N terminal like Ge1_WD40 PF16529.5 CBK21768.2 - 0.0075 15.3 0.0 2.7 6.8 0.0 3.0 2 1 1 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Y_phosphatase PF00102.27 CBK21769.2 - 1.6e-08 34.4 0.0 2e-08 34.1 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.20 CBK21769.2 - 9.6e-07 28.7 0.0 3.3e-06 27.0 0.0 1.9 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.6 CBK21769.2 - 0.0014 18.8 0.0 0.0022 18.1 0.0 1.3 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase3 PF13350.6 CBK21769.2 - 0.0014 18.6 0.0 0.0021 18.1 0.0 1.2 1 0 0 1 1 1 1 Tyrosine phosphatase family CDKN3 PF05706.12 CBK21769.2 - 0.025 14.2 0.0 0.04 13.6 0.0 1.2 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) Y_phosphatase2 PF03162.13 CBK21769.2 - 0.09 12.4 0.7 0.21 11.2 0.3 1.7 1 1 0 1 1 1 0 Tyrosine phosphatase family He_PIG PF05345.12 CBK21771.2 - 3.5e-07 30.3 0.0 7.5e-07 29.2 0.0 1.5 1 0 0 1 1 1 1 Putative Ig domain EphA2_TM PF14575.6 CBK21771.2 - 0.1 13.5 0.4 13 6.7 0.2 2.3 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain ELMO_CED12 PF04727.13 CBK21772.2 - 7.9e-28 97.8 0.3 1e-27 97.4 0.3 1.1 1 0 0 1 1 1 1 ELMO/CED-12 family DHHC PF01529.20 CBK21774.2 - 2e-18 66.8 9.0 2.3e-18 66.6 9.0 1.1 1 0 0 1 1 1 1 DHHC palmitoyltransferase PSI PF01437.25 CBK21774.2 - 0.008 16.7 1.6 0.011 16.3 1.6 1.2 1 0 0 1 1 1 1 Plexin repeat NHL PF01436.21 CBK21774.2 - 0.014 15.4 0.5 0.025 14.6 0.5 1.5 1 0 0 1 1 1 0 NHL repeat Fer4_2 PF12797.7 CBK21774.2 - 0.83 9.9 6.1 2.7 8.3 4.4 2.2 1 1 1 2 2 2 0 4Fe-4S binding domain SNF2_N PF00176.23 CBK21775.2 - 5.3e-60 203.0 0.1 1.1e-59 201.9 0.0 1.6 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 CBK21775.2 - 2.2e-15 56.9 0.0 9.2e-15 55.0 0.0 2.1 1 1 0 1 1 1 1 Helicase conserved C-terminal domain zf-RING_2 PF13639.6 CBK21775.2 - 1.2e-05 25.6 12.4 3.3e-05 24.1 12.4 1.8 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 CBK21775.2 - 1.9e-05 24.4 12.4 4.5e-05 23.2 12.4 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CBK21775.2 - 6e-05 22.9 14.0 0.00017 21.5 14.0 1.8 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 CBK21775.2 - 7.8e-05 22.6 11.3 0.00019 21.4 11.3 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 CBK21775.2 - 0.00077 19.3 13.4 0.0021 17.9 13.4 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 CBK21775.2 - 0.017 15.0 13.4 0.017 15.0 13.4 1.8 2 0 0 2 2 1 0 Zinc finger, C3HC4 type (RING finger) ResIII PF04851.15 CBK21775.2 - 0.019 15.0 0.0 0.091 12.8 0.0 2.1 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit zf-C3HC4_4 PF15227.6 CBK21775.2 - 0.019 15.1 13.8 0.048 13.8 13.8 1.8 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 CBK21775.2 - 0.16 11.8 13.2 0.97 9.3 13.4 2.1 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 zf-UDP PF14569.6 CBK21775.2 - 0.73 10.0 7.8 2.4 8.3 7.8 1.9 1 0 0 1 1 1 0 Zinc-binding RING-finger zf-Nse PF11789.8 CBK21775.2 - 1.7 8.5 10.0 6.9 6.6 9.7 2.3 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4_5 PF17121.5 CBK21775.2 - 5.5 6.9 13.5 23 4.9 13.5 2.1 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Pkinase PF00069.25 CBK21776.2 - 1.4e-57 195.1 0.1 1.7e-57 194.8 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBK21776.2 - 2.7e-22 79.3 0.0 5.1e-22 78.4 0.0 1.4 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.23 CBK21776.2 - 6.1e-06 26.3 6.3 1.1e-05 25.5 0.1 3.2 2 2 1 3 3 3 1 Phosphotransferase enzyme family Mtc PF03820.17 CBK21777.2 - 3.3e-07 29.6 0.0 4.3e-07 29.3 0.0 1.2 1 0 0 1 1 1 1 Tricarboxylate carrier PEPCK_ATP PF01293.20 CBK21778.2 - 0.003 16.3 0.0 0.0043 15.8 0.0 1.2 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase LTXXQ PF07813.12 CBK21780.2 - 0.0014 19.3 4.1 0.0059 17.3 1.3 2.6 2 1 0 2 2 2 1 LTXXQ motif family protein Mod_r PF07200.13 CBK21780.2 - 0.12 12.5 5.3 0.16 12.1 5.3 1.2 1 0 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein Dynamin_N PF00350.23 CBK21783.2 - 3.1e-13 50.1 0.0 1.5e-10 41.4 0.0 2.4 1 1 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.23 CBK21783.2 - 4.6e-08 33.2 0.0 1.9e-07 31.2 0.0 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 CBK21783.2 - 0.0037 16.8 0.9 0.081 12.4 0.0 2.9 3 0 0 3 3 3 1 Ferrous iron transport protein B ABC_tran PF00005.27 CBK21783.2 - 0.0051 17.3 0.0 0.61 10.6 0.0 2.4 2 0 0 2 2 2 1 ABC transporter RsgA_GTPase PF03193.16 CBK21783.2 - 0.014 15.3 0.0 1.8 8.5 0.0 2.8 3 0 0 3 3 3 0 RsgA GTPase Roc PF08477.13 CBK21783.2 - 0.021 15.0 0.0 8.1 6.7 0.0 2.8 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase Glyco_hydro_20 PF00728.22 CBK21783.2 - 0.022 14.2 0.1 0.033 13.6 0.1 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 20, catalytic domain YpsA PF06908.11 CBK21783.2 - 0.11 12.4 0.0 0.21 11.6 0.0 1.4 1 0 0 1 1 1 0 YspA SLOG family ER PF01133.17 CBK21785.2 - 0.00084 19.3 1.4 0.0027 17.7 0.1 2.5 4 0 0 4 4 4 1 Enhancer of rudimentary Pantoate_ligase PF02569.15 CBK21786.2 - 1.9e-92 309.2 0.0 2.2e-92 309.1 0.0 1.0 1 0 0 1 1 1 1 Pantoate-beta-alanine ligase Peptidase_M24 PF00557.24 CBK21787.2 - 1.3e-53 181.8 0.1 2.3e-53 181.0 0.0 1.4 2 0 0 2 2 2 1 Metallopeptidase family M24 zf-C6H2 PF15801.5 CBK21787.2 - 2.1e-15 56.7 10.4 4.8e-15 55.6 10.4 1.6 1 0 0 1 1 1 1 zf-MYND-like zinc finger, mRNA-binding zf-MYND PF01753.18 CBK21787.2 - 9.3e-06 25.6 10.6 2.2e-05 24.4 10.6 1.7 1 0 0 1 1 1 1 MYND finger WW PF00397.26 CBK21788.2 - 3.8e-08 33.3 8.2 6.4e-08 32.6 8.2 1.3 1 0 0 1 1 1 1 WW domain Adap_comp_sub PF00928.21 CBK21789.2 - 2.8e-58 197.4 0.1 3.9e-58 196.9 0.1 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 CBK21789.2 - 5e-06 26.5 0.0 9.4e-06 25.6 0.0 1.5 1 0 0 1 1 1 1 Clathrin adaptor complex small chain BRK PF07533.16 CBK21789.2 - 0.12 12.0 0.0 0.4 10.3 0.0 1.9 2 0 0 2 2 2 0 BRK domain Lung_7-TM_R PF06814.13 CBK21790.2 - 3.5e-48 164.3 23.4 4.3e-48 164.1 23.4 1.1 1 0 0 1 1 1 1 Lung seven transmembrane receptor GpcrRhopsn4 PF10192.9 CBK21790.2 - 1.1e-05 25.0 15.8 1.1e-05 25.0 15.8 1.9 1 1 1 2 2 2 1 Rhodopsin-like GPCR transmembrane domain RhoGAP PF00620.27 CBK21791.2 - 1.6e-21 76.7 0.0 1.3e-18 67.2 0.0 2.4 2 0 0 2 2 2 2 RhoGAP domain MyTH4 PF00784.17 CBK21791.2 - 8.1e-12 45.6 0.1 1.7e-11 44.5 0.1 1.6 1 0 0 1 1 1 1 MyTH4 domain Glyco_hydro_3 PF00933.21 CBK21792.2 - 8.4e-18 64.8 0.0 1.8e-16 60.4 0.0 2.0 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.22 CBK21793.2 - 2.5e-40 138.6 0.0 3.4e-40 138.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.6 CBK21793.2 - 9e-14 51.3 0.0 3.9e-13 49.3 0.0 2.1 3 0 0 3 3 3 1 Fibronectin type III-like domain UCH PF00443.29 CBK21794.2 - 5.2e-15 55.6 0.1 1.3e-14 54.3 0.1 1.7 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 CBK21794.2 - 0.00014 21.5 0.0 0.0004 20.1 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase LRR_4 PF12799.7 CBK21795.2 - 0.00049 20.4 1.1 0.28 11.7 0.2 3.4 3 1 1 4 4 4 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CBK21795.2 - 0.12 12.1 0.4 3.5 7.5 0.0 3.0 2 1 0 3 3 3 0 Leucine rich repeat RmlD_sub_bind PF04321.17 CBK21796.2 - 1e-15 57.6 0.0 2.2e-15 56.6 0.0 1.5 2 0 0 2 2 2 1 RmlD substrate binding domain Epimerase PF01370.21 CBK21796.2 - 1.2e-15 57.7 0.0 1.7e-15 57.1 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 CBK21796.2 - 2e-05 23.7 0.2 4.8e-05 22.5 0.0 1.6 1 1 1 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 CBK21796.2 - 0.00026 20.2 0.0 0.00043 19.5 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein GDP_Man_Dehyd PF16363.5 CBK21796.2 - 0.0018 17.7 0.1 0.043 13.2 0.0 2.2 1 1 1 2 2 2 1 GDP-mannose 4,6 dehydratase adh_short PF00106.25 CBK21796.2 - 0.0031 17.0 0.1 0.22 10.9 0.0 2.8 2 1 1 3 3 3 1 short chain dehydrogenase NAD_binding_4 PF07993.12 CBK21796.2 - 0.029 13.5 0.0 0.045 12.9 0.0 1.3 1 0 0 1 1 1 0 Male sterility protein DUF501 PF04417.12 CBK21796.2 - 0.085 12.7 0.0 0.14 12.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF501) Proteasome PF00227.26 CBK21797.2 - 3.6e-51 173.4 0.1 4.6e-51 173.0 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 CBK21797.2 - 2.3e-11 43.1 0.0 4e-11 42.4 0.0 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature SICA_C PF12879.7 CBK21797.2 - 0.05 13.6 0.2 8.1 6.5 0.1 2.3 2 0 0 2 2 2 0 SICA C-terminal inner membrane domain DUF5097 PF17020.5 CBK21797.2 - 0.058 13.7 0.0 0.13 12.6 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5097) DUF483 PF04467.12 CBK21797.2 - 0.095 12.7 0.0 0.15 12.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF483) HEAT PF02985.22 CBK21798.2 - 3.8e-06 26.7 1.5 2.2 8.8 0.0 5.2 6 0 0 6 6 6 2 HEAT repeat HEAT_2 PF13646.6 CBK21798.2 - 0.00084 19.7 0.0 0.054 13.9 0.0 3.0 3 1 0 3 3 3 1 HEAT repeats DUF1981 PF09324.10 CBK21798.2 - 0.074 12.9 0.2 4.5 7.2 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1981) DnaJ_C PF01556.18 CBK21799.2 - 2.2e-39 134.9 0.0 3e-39 134.5 0.0 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 CBK21799.2 - 4.2e-24 84.4 2.7 7.9e-24 83.6 2.7 1.4 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 CBK21799.2 - 1.1e-11 45.0 15.4 1.9e-11 44.2 15.4 1.4 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 CBK21799.2 - 2.3e-10 40.3 10.4 2.1e-06 27.6 0.8 2.4 2 0 0 2 2 2 2 Tryptophan RNA-binding attenuator protein inhibitory protein zf-TFIIB PF13453.6 CBK21799.2 - 0.061 12.7 10.5 0.9 8.9 1.9 3.4 3 0 0 3 3 3 0 Transcription factor zinc-finger Lar_restr_allev PF14354.6 CBK21799.2 - 0.099 13.0 14.6 1.2 9.6 0.2 3.9 1 1 3 4 4 4 0 Restriction alleviation protein Lar HypA PF01155.19 CBK21799.2 - 0.9 9.6 11.1 0.87 9.6 2.6 2.3 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA TackOD1 PF18551.1 CBK21799.2 - 0.99 9.0 10.1 0.27 10.9 0.5 2.3 1 1 1 2 2 2 0 Thaumarchaeal output domain 1 DZR PF12773.7 CBK21799.2 - 2.4 8.2 14.3 46 4.1 14.3 2.4 1 1 0 1 1 1 0 Double zinc ribbon DUF5351 PF17302.2 CBK21799.2 - 3.4 7.9 22.4 5.8 7.2 0.3 4.8 5 0 0 5 5 5 0 Family of unknown function (DUF5351) MFS_1 PF07690.16 CBK21800.2 - 0.0025 16.8 0.4 0.0028 16.6 0.4 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_1 PF07690.16 CBK21801.2 - 1.5e-13 50.4 11.8 1.8e-13 50.2 11.8 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 CBK21801.2 - 1.6e-06 27.3 6.8 4.1e-05 22.6 6.8 2.5 1 1 0 1 1 1 1 Sugar (and other) transporter Myb_DNA-binding PF00249.31 CBK21802.2 - 0.00075 19.6 0.0 0.0016 18.6 0.0 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain HHH_9 PF17674.1 CBK21802.2 - 0.16 12.9 0.4 0.27 12.2 0.4 1.3 1 0 0 1 1 1 0 HHH domain GNAT_acetyltr_2 PF13718.6 CBK21803.2 - 1.1e-93 312.9 0.1 5.2e-93 310.6 0.0 2.0 2 0 0 2 2 2 1 GNAT acetyltransferase 2 tRNA_bind_2 PF13725.6 CBK21803.2 - 3.7e-61 206.8 6.7 3.7e-61 206.8 6.7 1.8 2 0 0 2 2 2 1 Possible tRNA binding domain Helicase_RecD PF05127.14 CBK21803.2 - 7.9e-61 205.0 0.0 1.6e-60 204.0 0.0 1.5 1 0 0 1 1 1 1 Helicase DUF1726 PF08351.11 CBK21803.2 - 7e-32 109.2 0.0 1.8e-31 107.9 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1726) AAA_30 PF13604.6 CBK21803.2 - 0.00015 21.6 0.3 0.006 16.3 0.1 2.4 2 0 0 2 2 2 1 AAA domain Acetyltransf_7 PF13508.7 CBK21803.2 - 0.00066 20.1 0.0 0.019 15.3 0.0 2.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Mis12 PF05859.12 CBK21803.2 - 0.0024 17.9 0.7 0.0075 16.3 0.7 1.8 1 0 0 1 1 1 1 Mis12 protein Auxin_resp PF06507.13 CBK21803.2 - 0.013 15.8 0.2 0.027 14.7 0.2 1.5 1 0 0 1 1 1 0 Auxin response factor AAA_22 PF13401.6 CBK21803.2 - 0.072 13.4 1.0 15 5.8 0.0 3.6 4 0 0 4 4 4 0 AAA domain Acetyltransf_1 PF00583.25 CBK21803.2 - 0.11 12.7 0.0 0.35 11.1 0.0 1.8 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family TetR_C_15 PF17918.1 CBK21803.2 - 0.25 12.1 2.4 0.36 11.6 0.1 2.5 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain BLYB PF05289.11 CBK21806.2 - 0.14 12.4 0.0 0.2 11.9 0.0 1.2 1 0 0 1 1 1 0 Borrelia hemolysin accessory protein FAD_binding_1 PF00667.20 CBK21807.2 - 1.5e-54 185.0 0.0 1.9e-54 184.6 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 CBK21807.2 - 6.8e-23 81.5 0.1 1.1e-22 80.8 0.1 1.3 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.21 CBK21807.2 - 5.4e-11 43.1 0.0 1e-10 42.2 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain DUF4091 PF13320.6 CBK21807.2 - 0.16 12.1 0.1 28 4.9 0.0 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4091) DNA_pol_B_exo1 PF03104.19 CBK21808.2 - 1.2e-07 31.2 0.0 2.8e-07 30.0 0.0 1.7 1 1 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_B PF00136.21 CBK21809.2 - 1.3e-76 258.2 1.1 2.8e-72 243.9 0.3 2.0 2 0 0 2 2 2 2 DNA polymerase family B zf-C4pol PF14260.6 CBK21809.2 - 0.037 14.5 0.1 0.089 13.3 0.1 1.6 1 0 0 1 1 1 0 C4-type zinc-finger of DNA polymerase delta DNA_pol_B_2 PF03175.13 CBK21809.2 - 0.04 12.8 0.0 0.07 12.0 0.0 1.4 1 0 0 1 1 1 0 DNA polymerase type B, organellar and viral He_PIG PF05345.12 CBK21810.2 - 0.00056 20.0 0.4 0.0015 18.7 0.4 1.8 1 0 0 1 1 1 1 Putative Ig domain Tmemb_9 PF05434.11 CBK21810.2 - 0.079 12.8 0.9 0.14 12.1 0.9 1.3 1 0 0 1 1 1 0 TMEM9 RIFIN PF02009.16 CBK21810.2 - 0.15 11.9 1.7 0.23 11.3 1.7 1.2 1 0 0 1 1 1 0 Rifin TMEM154 PF15102.6 CBK21810.2 - 0.17 11.8 2.8 0.32 10.9 2.8 1.4 1 0 0 1 1 1 0 TMEM154 protein family DUF4834 PF16118.5 CBK21810.2 - 0.36 11.8 1.5 0.67 11.0 1.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) HemY_N PF07219.13 CBK21810.2 - 0.39 10.9 1.6 0.71 10.1 1.6 1.3 1 0 0 1 1 1 0 HemY protein N-terminus Shisa PF13908.6 CBK21810.2 - 0.47 10.7 2.2 0.81 9.9 2.2 1.4 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator EphA2_TM PF14575.6 CBK21810.2 - 0.73 10.8 3.9 1.3 9.9 3.9 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain SRTM1 PF15872.5 CBK21810.2 - 1.8 8.7 5.0 7.4 6.8 0.1 2.4 2 0 0 2 2 2 0 Serine-rich and transmembrane domain-containing protein 1 Baculo_11_kDa PF06143.11 CBK21810.2 - 1.9 8.1 6.6 3.8 7.1 6.6 1.4 1 0 0 1 1 1 0 Baculovirus 11 kDa family UvrD_C PF13361.6 CBK21811.2 - 0.12 11.8 2.4 0.14 11.5 2.4 1.1 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain Com_YlbF PF06133.11 CBK21811.2 - 6.5 7.4 11.0 2.9 8.6 4.8 2.5 2 1 0 2 2 2 0 Control of competence regulator ComK, YlbF/YmcA FH2 PF02181.23 CBK21812.2 - 1.8e-44 152.4 2.0 4.5e-44 151.1 2.0 1.6 1 0 0 1 1 1 1 Formin Homology 2 Domain Drf_FH3 PF06367.16 CBK21812.2 - 5.4e-16 58.8 2.4 2.1e-15 56.8 2.4 2.1 1 0 0 1 1 1 1 Diaphanous FH3 Domain CCDC53 PF10152.9 CBK21812.2 - 1e-12 48.7 8.2 4e-08 33.8 0.0 3.2 4 0 0 4 4 4 2 Subunit CCDC53 of WASH complex Drf_GBD PF06371.13 CBK21812.2 - 4e-07 29.8 0.1 4e-07 29.8 0.1 3.0 3 0 0 3 3 3 1 Diaphanous GTPase-binding Domain Imm42 PF15593.6 CBK21812.2 - 0.57 10.7 6.7 0.05 14.1 0.8 2.3 3 0 0 3 3 3 0 Immunity protein 42 KELK PF15796.5 CBK21812.2 - 1 9.8 8.5 0.22 12.0 2.3 3.0 2 1 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase RNA_binding PF01877.17 CBK21812.2 - 9.8 6.5 8.9 9.6 6.5 0.9 3.5 4 0 0 4 4 4 0 RNA binding FAD_binding_2 PF00890.24 CBK21813.2 - 4e-121 405.0 3.1 5.3e-121 404.6 3.1 1.2 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.20 CBK21813.2 - 2.4e-44 150.4 1.8 3.5e-44 149.9 1.8 1.3 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term Thi4 PF01946.17 CBK21813.2 - 5.1e-06 25.9 0.1 0.0067 15.7 0.1 2.6 3 0 0 3 3 3 2 Thi4 family GIDA PF01134.22 CBK21813.2 - 5.4e-05 22.4 0.9 0.003 16.7 1.0 2.2 2 0 0 2 2 2 1 Glucose inhibited division protein A Pyr_redox_2 PF07992.14 CBK21813.2 - 0.0001 21.6 0.3 0.00029 20.2 0.2 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 CBK21813.2 - 0.00023 20.9 0.4 0.00039 20.1 0.4 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 CBK21813.2 - 0.00023 20.5 0.2 0.00041 19.7 0.2 1.4 1 0 0 1 1 1 1 FAD binding domain NAD_binding_7 PF13241.6 CBK21813.2 - 0.019 15.4 0.0 0.8 10.2 0.0 2.4 2 0 0 2 2 2 0 Putative NAD(P)-binding HI0933_like PF03486.14 CBK21813.2 - 0.029 13.1 1.6 0.051 12.3 0.3 2.0 3 0 0 3 3 3 0 HI0933-like protein DNA_pol_B_2 PF03175.13 CBK21814.2 - 8.2e-17 61.2 13.6 6.8e-14 51.6 8.5 2.3 2 0 0 2 2 2 2 DNA polymerase type B, organellar and viral Peptidase_C13 PF01650.18 CBK21815.2 - 9.9e-95 316.9 0.1 1.3e-94 316.5 0.1 1.2 1 0 0 1 1 1 1 Peptidase C13 family Peptidase_C14 PF00656.22 CBK21815.2 - 0.12 12.3 0.0 0.14 12.0 0.0 1.4 1 1 0 1 1 1 0 Caspase domain NIF PF03031.18 CBK21816.2 - 3.8e-49 166.4 0.4 5.5e-49 165.9 0.4 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Hydrolase PF00702.26 CBK21816.2 - 0.22 11.8 0.0 3.2 8.0 0.0 2.1 1 1 1 2 2 2 0 haloacid dehalogenase-like hydrolase Ribosomal_S3Ae PF01015.18 CBK21817.2 - 3.2e-83 278.3 3.1 5e-83 277.6 3.1 1.3 1 0 0 1 1 1 1 Ribosomal S3Ae family Metallophos PF00149.28 CBK21817.2 - 2e-09 38.2 0.1 3.5e-09 37.5 0.1 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase SUI1 PF01253.22 CBK21817.2 - 0.005 17.3 0.2 0.017 15.7 0.2 1.9 1 1 0 1 1 1 1 Translation initiation factor SUI1 Abhydro_lipase PF04083.16 CBK21817.2 - 0.056 13.0 0.0 0.2 11.3 0.0 1.9 1 0 0 1 1 1 0 Partial alpha/beta-hydrolase lipase region AlcCBM31 PF11606.8 CBK21817.2 - 0.067 13.4 0.2 0.71 10.1 0.1 2.4 2 0 0 2 2 2 0 Family 31 carbohydrate binding protein IPPT PF01715.17 CBK21818.2 - 4e-59 200.2 0.1 6.6e-59 199.5 0.1 1.3 1 0 0 1 1 1 1 IPP transferase GAS PF13851.6 CBK21819.2 - 0.00094 18.6 5.4 0.11 11.9 0.8 2.1 2 0 0 2 2 2 2 Growth-arrest specific micro-tubule binding Dynactin_p22 PF07426.11 CBK21819.2 - 0.002 18.0 11.0 0.0058 16.5 10.9 1.8 1 1 0 1 1 1 1 Dynactin subunit p22 BLOC1_2 PF10046.9 CBK21819.2 - 0.0037 17.5 8.5 0.51 10.7 0.2 2.7 3 1 0 3 3 2 2 Biogenesis of lysosome-related organelles complex-1 subunit 2 Spectrin PF00435.21 CBK21819.2 - 0.008 16.7 2.0 0.053 14.0 0.3 2.3 2 0 0 2 2 2 1 Spectrin repeat DUF1664 PF07889.12 CBK21819.2 - 0.011 15.8 4.4 0.28 11.2 0.9 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) YtxH PF12732.7 CBK21819.2 - 0.017 15.6 0.2 0.06 13.9 0.2 2.1 1 1 0 1 1 1 0 YtxH-like protein Mod_r PF07200.13 CBK21819.2 - 0.02 15.0 6.3 0.77 9.9 2.2 2.4 2 1 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein TMF_TATA_bd PF12325.8 CBK21819.2 - 0.022 15.0 11.2 0.4 10.9 0.9 2.5 2 1 0 2 2 2 0 TATA element modulatory factor 1 TATA binding DUF948 PF06103.11 CBK21819.2 - 0.044 14.0 1.2 9 6.6 0.0 3.0 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) NPV_P10 PF05531.12 CBK21819.2 - 0.048 14.1 2.1 6 7.4 0.9 2.8 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF4988 PF16378.5 CBK21819.2 - 0.069 12.8 6.5 2.7 7.6 0.1 3.3 3 1 0 3 3 3 0 Domain of unknown function rRNA_proc-arch PF13234.6 CBK21819.2 - 0.069 13.1 3.4 0.97 9.3 0.2 2.4 2 1 0 2 2 2 0 rRNA-processing arch domain SKA2 PF16740.5 CBK21819.2 - 0.12 12.2 7.4 3.6 7.4 0.2 3.3 2 2 1 3 3 3 0 Spindle and kinetochore-associated protein 2 KxDL PF10241.9 CBK21819.2 - 0.12 12.7 2.8 4 7.8 0.4 2.5 2 1 0 2 2 2 0 Uncharacterized conserved protein XhlA PF10779.9 CBK21819.2 - 0.17 12.1 5.6 11 6.3 0.0 3.3 3 0 0 3 3 3 0 Haemolysin XhlA LPP PF04728.13 CBK21819.2 - 0.18 12.2 3.8 10 6.6 0.3 3.3 3 1 0 3 3 3 0 Lipoprotein leucine-zipper HalX PF08663.10 CBK21819.2 - 0.2 12.0 3.3 26 5.2 0.2 3.6 3 3 1 4 4 4 0 HalX domain YabA PF06156.13 CBK21819.2 - 0.22 12.2 7.9 1.7 9.3 0.2 3.0 1 1 1 3 3 3 0 Initiation control protein YabA Cytochrom_B562 PF07361.11 CBK21819.2 - 0.23 12.1 1.8 1.3 9.8 0.1 2.6 2 2 0 2 2 2 0 Cytochrome b562 Sec8_exocyst PF04048.14 CBK21819.2 - 0.25 11.2 4.6 4.2 7.3 2.0 2.5 2 1 0 2 2 2 0 Sec8 exocyst complex component specific domain DUF5082 PF16888.5 CBK21819.2 - 0.29 11.4 9.5 5.1 7.4 0.1 3.4 1 1 2 3 3 3 0 Domain of unknown function (DUF5082) SlyX PF04102.12 CBK21819.2 - 0.3 11.7 4.5 11 6.7 0.4 3.0 3 0 0 3 3 3 0 SlyX HMMR_N PF15905.5 CBK21819.2 - 0.34 10.3 9.7 1.5 8.3 0.4 2.1 1 1 1 2 2 2 0 Hyaluronan mediated motility receptor N-terminal Seryl_tRNA_N PF02403.22 CBK21819.2 - 0.39 11.0 3.7 13 6.1 0.3 2.4 2 1 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain ADIP PF11559.8 CBK21819.2 - 0.47 10.5 6.7 7.4 6.6 2.8 2.5 2 1 0 2 2 2 0 Afadin- and alpha -actinin-Binding DUF1192 PF06698.11 CBK21819.2 - 0.48 10.5 3.2 7.7 6.6 0.1 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1192) Snapin_Pallidin PF14712.6 CBK21819.2 - 0.56 10.7 6.4 5.9 7.4 1.5 3.0 1 1 2 3 3 3 0 Snapin/Pallidin CC2-LZ PF16516.5 CBK21819.2 - 0.6 10.5 4.0 2 8.8 0.2 2.6 1 1 1 2 2 2 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator Helo_like_N PF17111.5 CBK21819.2 - 0.62 9.4 9.7 0.5 9.7 0.5 2.8 2 1 1 3 3 3 0 Fungal N-terminal domain of STAND proteins FlaC_arch PF05377.11 CBK21819.2 - 0.7 10.3 9.7 18 5.8 0.4 3.4 3 1 1 4 4 4 0 Flagella accessory protein C (FlaC) DUF4795 PF16043.5 CBK21819.2 - 0.81 9.3 7.1 12 5.5 0.4 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF4795) DASH_Duo1 PF08651.10 CBK21819.2 - 1 9.1 7.3 2.1 8.2 0.3 3.7 2 1 1 4 4 4 0 DASH complex subunit Duo1 DUF16 PF01519.16 CBK21819.2 - 2.2 8.8 6.2 7.5 7.1 0.2 2.8 1 1 1 2 2 2 0 Protein of unknown function DUF16 Vps51 PF08700.11 CBK21819.2 - 2.3 8.4 7.8 3.2 7.9 0.3 3.6 3 2 0 3 3 3 0 Vps51/Vps67 Fib_alpha PF08702.10 CBK21819.2 - 4.6 7.4 11.0 4 7.6 4.1 2.2 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family TSC22 PF01166.18 CBK21819.2 - 5.9 7.3 9.0 1.7 9.0 0.5 3.7 2 2 3 5 5 5 0 TSC-22/dip/bun family ZapB PF06005.12 CBK21819.2 - 8.1 7.0 9.5 13 6.4 0.4 3.0 2 1 0 2 2 2 0 Cell division protein ZapB Lung_7-TM_R PF06814.13 CBK21820.2 - 2.3e-20 73.1 2.9 3.2e-20 72.6 2.9 1.2 1 0 0 1 1 1 1 Lung seven transmembrane receptor AveC_like PF17198.4 CBK21820.2 - 0.068 12.6 1.3 0.1 12.0 1.3 1.2 1 0 0 1 1 1 0 Spirocyclase AveC-like DUF1724 PF08350.10 CBK21820.2 - 0.12 12.5 0.1 4.6 7.5 0.0 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF1724) Sec62 PF03839.16 CBK21820.2 - 1.9 8.0 6.6 4.1 6.9 6.6 1.6 1 0 0 1 1 1 0 Translocation protein Sec62 TAL_FSA PF00923.19 CBK21823.2 - 2.4e-95 319.2 0.0 2.8e-95 319.0 0.0 1.0 1 0 0 1 1 1 1 Transaldolase/Fructose-6-phosphate aldolase CTNNBL PF08216.11 CBK21824.2 - 7.5e-28 96.7 1.2 7.5e-28 96.7 1.2 2.3 3 0 0 3 3 3 1 Catenin-beta-like, Arm-motif containing nuclear Urocanase_N PF17391.2 CBK21824.2 - 0.077 12.7 0.0 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 Urocanase N-terminal domain Myb_DNA-binding PF00249.31 CBK21825.2 - 1.5e-14 53.9 0.6 2.3e-14 53.3 0.6 1.3 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 CBK21825.2 - 4e-06 26.6 1.2 5.8e-06 26.1 1.2 1.3 1 1 0 1 1 1 1 Myb DNA-binding like Myb_DNA-bind_6 PF13921.6 CBK21825.2 - 0.00033 20.8 0.6 0.00049 20.3 0.6 1.3 1 0 0 1 1 1 1 Myb-like DNA-binding domain Ribosomal_S4e PF00900.20 CBK21826.2 - 2.1e-32 110.8 0.7 6.5e-32 109.3 0.7 1.8 1 0 0 1 1 1 1 Ribosomal family S4e 40S_S4_C PF16121.5 CBK21826.2 - 5e-26 90.1 0.0 8.9e-26 89.3 0.0 1.4 1 0 0 1 1 1 1 40S ribosomal protein S4 C-terminus KOW PF00467.29 CBK21826.2 - 0.00011 22.1 2.1 0.00011 22.1 2.1 3.0 4 0 0 4 4 4 1 KOW motif S4 PF01479.25 CBK21826.2 - 0.0044 16.7 0.2 0.01 15.5 0.0 1.8 2 0 0 2 2 2 1 S4 domain DUF4056 PF13265.6 CBK21826.2 - 0.23 10.8 0.4 0.39 10.0 0.3 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF4056) Clat_adaptor_s PF01217.20 CBK21827.2 - 5.4e-17 62.1 1.9 6.2e-17 61.9 1.9 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain DUF1977 PF09320.11 CBK21827.2 - 0.08 13.2 0.1 0.094 13.0 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1977) Glycos_transf_4 PF00953.21 CBK21828.2 - 1.1e-36 126.3 3.0 1.1e-36 126.3 3.0 1.8 2 1 0 2 2 2 1 Glycosyl transferase family 4 DUF3392 PF11872.8 CBK21828.2 - 0.0051 17.0 0.2 0.0051 17.0 0.2 2.2 2 1 0 2 2 2 1 Protein of unknown function (DUF3392) Pigment_DH PF06324.11 CBK21828.2 - 3.1 8.1 5.6 3.1 8.1 0.3 2.6 2 0 0 2 2 2 0 Pigment-dispersing hormone (PDH) AAA_5 PF07728.14 CBK21830.2 - 1.7e-56 190.0 0.0 3.2e-13 49.9 0.0 6.7 6 0 0 6 6 6 5 AAA domain (dynein-related subfamily) AAA_7 PF12775.7 CBK21830.2 - 3.5e-16 59.2 1.3 0.0027 17.3 0.0 5.6 6 0 0 6 6 6 4 P-loop containing dynein motor region AAA_3 PF07726.11 CBK21830.2 - 9.5e-13 48.1 0.0 1.9e-07 31.0 0.0 3.5 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 CBK21830.2 - 1.1e-11 44.9 0.0 0.0028 17.7 0.0 5.5 4 0 0 4 4 4 3 AAA domain Dynein_heavy PF03028.15 CBK21830.2 - 6.2e-11 42.4 0.0 1.5e-05 25.1 0.0 4.6 3 1 1 4 4 4 1 Dynein heavy chain region D6 P-loop domain AAA_22 PF13401.6 CBK21830.2 - 7.9e-10 39.1 1.3 0.36 11.1 0.1 6.9 6 2 0 6 6 6 2 AAA domain AAA PF00004.29 CBK21830.2 - 2.6e-07 31.1 0.5 0.078 13.4 0.0 5.6 5 0 0 5 5 5 2 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 CBK21830.2 - 3.9e-07 29.9 0.0 0.0076 16.0 0.0 4.4 5 0 0 5 5 5 2 Sigma-54 interaction domain AAA_16 PF13191.6 CBK21830.2 - 7.8e-06 26.4 0.0 2.2 8.6 0.0 5.5 5 0 0 5 5 5 1 AAA ATPase domain AAA_33 PF13671.6 CBK21830.2 - 0.00037 20.7 0.0 3.2 7.9 0.0 4.3 5 0 0 5 5 4 1 AAA domain AAA_18 PF13238.6 CBK21830.2 - 0.0075 16.8 0.0 28 5.2 0.0 4.7 3 0 0 3 3 3 0 AAA domain Viral_helicase1 PF01443.18 CBK21830.2 - 0.011 15.4 0.0 2.2 8.0 0.0 3.4 3 0 0 3 3 3 0 Viral (Superfamily 1) RNA helicase AAA_24 PF13479.6 CBK21830.2 - 0.012 15.3 1.3 18 4.9 0.0 4.5 4 0 0 4 4 4 0 AAA domain TsaE PF02367.17 CBK21830.2 - 0.014 15.4 0.0 15 5.6 0.0 4.2 4 0 0 4 4 4 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ABC_tran PF00005.27 CBK21830.2 - 0.024 15.1 0.0 13 6.3 0.0 3.4 2 0 0 2 2 2 0 ABC transporter AAA_30 PF13604.6 CBK21830.2 - 0.034 13.9 0.0 5.7 6.6 0.0 4.0 5 0 0 5 5 4 0 AAA domain FtsK_SpoIIIE PF01580.18 CBK21830.2 - 0.076 12.3 0.3 57 2.9 0.3 3.7 4 0 0 4 4 4 0 FtsK/SpoIIIE family DASH_Duo1 PF08651.10 CBK21830.2 - 0.4 10.5 3.2 0.59 9.9 0.4 3.0 2 0 0 2 2 1 0 DASH complex subunit Duo1 RNA_helicase PF00910.22 CBK21830.2 - 4.3 7.8 10.7 4 7.9 0.0 5.1 5 0 0 5 5 4 0 RNA helicase XPG_I PF00867.18 CBK21831.2 - 3.5e-21 75.3 0.3 7.4e-21 74.3 0.1 1.6 2 0 0 2 2 2 1 XPG I-region XPG_N PF00752.17 CBK21831.2 - 4.9e-15 55.9 0.0 7.8e-15 55.2 0.0 1.3 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I_2 PF12813.7 CBK21831.2 - 0.00034 20.2 0.3 0.00089 18.8 0.1 1.6 1 1 1 2 2 2 1 XPG domain containing Adaptin_N PF01602.20 CBK21832.2 - 4.3e-139 464.4 15.1 5.2e-139 464.2 15.1 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 CBK21832.2 - 1.1e-62 210.8 13.8 2.8e-60 203.0 1.8 3.8 3 1 1 4 4 4 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 CBK21832.2 - 2e-18 66.6 1.9 8.5e-07 29.3 0.0 6.4 2 2 4 7 7 7 4 HEAT repeats HEAT PF02985.22 CBK21832.2 - 1.5e-11 43.5 5.6 0.0051 17.0 0.0 7.5 7 0 0 7 7 7 2 HEAT repeat Cnd3 PF12719.7 CBK21832.2 - 3.4e-08 33.0 0.9 3.9e-05 23.0 0.0 3.0 2 1 0 2 2 2 2 Nuclear condensing complex subunits, C-term domain RTP1_C1 PF10363.9 CBK21832.2 - 5.7e-08 32.9 4.0 0.00095 19.3 0.0 4.9 2 2 2 4 4 4 1 Required for nuclear transport of RNA pol II C-terminus 1 Arm PF00514.23 CBK21832.2 - 3e-05 23.9 0.6 0.24 11.5 0.0 4.8 5 0 0 5 5 5 1 Armadillo/beta-catenin-like repeat CLASP_N PF12348.8 CBK21832.2 - 0.00016 21.3 1.5 0.35 10.4 0.0 3.7 2 1 1 3 3 3 1 CLASP N terminal UNC45-central PF11701.8 CBK21832.2 - 0.0065 16.4 2.3 1.2 9.1 0.2 4.1 4 1 0 4 4 4 1 Myosin-binding striated muscle assembly central Arm_2 PF04826.13 CBK21832.2 - 0.022 14.3 1.2 0.21 11.0 0.0 2.5 2 0 0 2 2 2 0 Armadillo-like Sec7_N PF12783.7 CBK21832.2 - 0.025 14.5 4.3 0.076 12.9 0.3 3.2 2 1 0 3 3 3 0 Guanine nucleotide exchange factor in Golgi transport N-terminal DNA_pol_phi PF04931.13 CBK21832.2 - 0.26 9.3 51.2 1 7.4 47.5 3.0 3 0 0 3 3 3 0 DNA polymerase phi DUF913 PF06025.12 CBK21832.2 - 0.46 9.4 4.3 0.86 8.5 3.8 1.8 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) CNDH2_C PF16858.5 CBK21832.2 - 0.54 10.1 14.4 0.86 9.4 14.4 1.4 1 0 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term DUF5578 PF17741.1 CBK21832.2 - 4 6.8 10.6 4.1 6.8 0.4 4.3 3 1 1 5 5 5 0 Family of unknown function (DUF5578) SDA1 PF05285.12 CBK21832.2 - 8.7 5.7 41.5 15 4.9 41.5 1.3 1 0 0 1 1 1 0 SDA1 ATP-grasp_5 PF13549.6 CBK21833.2 - 3.8e-78 262.0 0.6 6.4e-78 261.2 0.0 1.7 2 0 0 2 2 2 1 ATP-grasp domain Succ_CoA_lig PF13607.6 CBK21833.2 - 3.5e-57 192.1 0.5 1.1e-56 190.5 0.5 1.9 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.6 CBK21833.2 - 3.7e-23 82.2 2.0 5.1e-22 78.5 0.1 3.2 3 0 0 3 3 3 1 CoA binding domain CoA_binding PF02629.19 CBK21833.2 - 1.6e-13 51.2 0.8 4.9e-13 49.6 0.1 2.4 2 0 0 2 2 1 1 CoA binding domain Acetyltransf_1 PF00583.25 CBK21833.2 - 2.4e-09 37.4 0.1 4.8e-09 36.5 0.1 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_3 PF13302.7 CBK21833.2 - 9.9e-06 26.3 0.0 2.4e-05 25.0 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain ATP-grasp_2 PF08442.10 CBK21833.2 - 7.5e-05 22.4 0.1 0.00021 20.9 0.1 1.8 1 0 0 1 1 1 1 ATP-grasp domain Acetyltransf_4 PF13420.7 CBK21833.2 - 0.00013 22.2 0.0 0.00029 21.0 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 CBK21833.2 - 0.00032 20.8 0.9 0.0044 17.1 0.1 2.9 3 0 0 3 3 3 1 GCN5-related N-acetyl-transferase Acetyltransf_10 PF13673.7 CBK21833.2 - 0.0041 17.1 0.1 0.0086 16.0 0.1 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 CBK21833.2 - 0.011 16.1 0.0 0.027 14.9 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain CPSase_L_D2 PF02786.17 CBK21833.2 - 0.011 15.2 0.1 0.034 13.7 0.1 1.8 1 0 0 1 1 1 0 Carbamoyl-phosphate synthase L chain, ATP binding domain Pkinase PF00069.25 CBK21834.2 - 6e-30 104.5 0.0 1.2e-29 103.5 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBK21834.2 - 1.7e-10 40.6 0.0 5.1e-10 39.1 0.0 1.8 2 1 0 2 2 2 1 Protein tyrosine kinase Kdo PF06293.14 CBK21834.2 - 0.011 15.1 0.1 0.071 12.4 0.1 2.1 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 CBK21834.2 - 0.1 12.2 0.1 0.28 10.8 0.0 1.7 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Pox_ser-thr_kin PF05445.11 CBK21834.2 - 0.11 11.4 0.0 0.18 10.8 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Bac_export_2 PF01312.19 CBK21836.2 - 0.026 13.7 2.1 0.034 13.4 1.7 1.4 1 1 0 1 1 1 0 FlhB HrpN YscU SpaS Family adh_short PF00106.25 CBK21837.2 - 6e-28 97.6 0.7 8e-28 97.2 0.7 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CBK21837.2 - 1e-14 54.7 0.1 1.4e-14 54.2 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CBK21837.2 - 2.3e-07 30.9 0.3 3.4e-07 30.3 0.3 1.3 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 CBK21837.2 - 0.013 15.4 0.1 0.055 13.4 0.1 1.8 2 0 0 2 2 2 0 NAD(P)H-binding NmrA PF05368.13 CBK21837.2 - 0.054 13.0 0.2 0.13 11.8 0.2 1.6 2 0 0 2 2 2 0 NmrA-like family AAR2 PF05282.11 CBK21838.2 - 7.3e-50 170.3 9.1 3.3e-31 109.0 0.1 2.0 1 1 1 2 2 2 2 AAR2 protein Rep_3 PF01051.21 CBK21838.2 - 0.23 11.3 5.5 2.9 7.7 0.4 2.1 2 0 0 2 2 2 0 Initiator Replication protein MORN PF02493.20 CBK21839.2 - 3.6e-06 26.5 25.9 0.043 13.7 1.9 8.0 9 0 0 9 9 9 3 MORN repeat MORN_2 PF07661.13 CBK21839.2 - 0.0076 16.3 0.1 6.8 7.3 0.0 4.6 4 0 0 4 4 4 1 MORN repeat variant LRR_8 PF13855.6 CBK21839.2 - 0.017 14.9 0.5 0.31 10.8 0.4 2.5 2 1 0 2 2 2 0 Leucine rich repeat Pro_isomerase PF00160.21 CBK21840.2 - 8.2e-24 84.7 0.0 1.8e-23 83.6 0.0 1.5 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Glyco_transf_4 PF13439.6 CBK21841.2 - 7.6e-28 97.6 0.0 1.1e-27 97.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase Family 4 PIGA PF08288.12 CBK21841.2 - 1.2e-23 83.4 0.9 2.7e-23 82.4 0.9 1.5 1 0 0 1 1 1 1 PIGA (GPI anchor biosynthesis) Glycos_transf_1 PF00534.20 CBK21841.2 - 9.9e-15 54.5 0.0 2e-14 53.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 CBK21841.2 - 9.4e-13 48.7 0.0 1.8e-12 47.8 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 CBK21841.2 - 1e-05 26.0 0.0 1.5e-05 25.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_4_2 PF13477.6 CBK21841.2 - 0.0003 20.8 0.1 0.0005 20.1 0.1 1.3 1 0 0 1 1 1 1 Glycosyl transferase 4-like Glyco_trans_1_2 PF13524.6 CBK21841.2 - 0.023 15.1 0.0 0.084 13.3 0.0 1.9 2 0 0 2 2 2 0 Glycosyl transferases group 1 Glyco_transf_5 PF08323.11 CBK21841.2 - 0.097 12.4 0.4 3.7 7.2 0.4 2.1 1 1 0 1 1 1 0 Starch synthase catalytic domain Actin PF00022.19 CBK21842.2 - 8.2e-09 34.6 0.0 0.00012 20.8 0.0 2.1 1 1 1 2 2 2 2 Actin BRO1 PF03097.18 CBK21843.2 - 1.1e-22 80.4 0.0 1.4e-22 80.1 0.0 1.0 1 0 0 1 1 1 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.6 CBK21844.2 - 1.1e-07 31.5 14.4 3.9e-07 29.7 2.9 3.0 2 1 1 3 3 3 2 ALIX V-shaped domain binding to HIV Snapin_Pallidin PF14712.6 CBK21844.2 - 0.00086 19.7 3.6 0.0014 19.0 0.8 2.7 2 1 0 2 2 2 1 Snapin/Pallidin Methyltransf_22 PF13383.6 CBK21844.2 - 0.021 14.4 0.9 0.033 13.8 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase domain TMPIT PF07851.13 CBK21844.2 - 0.21 10.8 2.1 1.9 7.6 0.0 2.3 1 1 1 2 2 2 0 TMPIT-like protein Methyltransf_5 PF01795.19 CBK21845.2 - 5.6e-52 177.2 0.0 6.8e-52 176.9 0.0 1.0 1 0 0 1 1 1 1 MraW methylase family PseudoU_synth_2 PF00849.22 CBK21846.2 - 1.4e-31 109.8 0.0 2e-31 109.2 0.0 1.3 1 0 0 1 1 1 1 RNA pseudouridylate synthase S4 PF01479.25 CBK21846.2 - 1.1e-05 25.1 0.0 2.7e-05 23.8 0.0 1.7 1 0 0 1 1 1 1 S4 domain Ub-Mut7C PF14451.6 CBK21846.2 - 0.022 14.6 0.0 0.049 13.5 0.0 1.5 1 0 0 1 1 1 0 Mut7-C ubiquitin ThiS PF02597.20 CBK21846.2 - 0.024 15.3 0.0 0.058 14.0 0.0 1.6 1 0 0 1 1 1 0 ThiS family TGS PF02824.21 CBK21846.2 - 0.064 13.3 0.1 0.21 11.7 0.1 1.8 2 0 0 2 2 2 0 TGS domain Hist_deacetyl PF00850.19 CBK21848.2 - 1.3e-17 64.3 0.0 2.3e-17 63.5 0.0 1.3 1 0 0 1 1 1 1 Histone deacetylase domain PHD PF00628.29 CBK21848.2 - 4.9e-06 26.4 6.4 1e-05 25.3 6.4 1.5 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 CBK21848.2 - 0.02 14.4 4.0 0.04 13.5 4.0 1.4 1 0 0 1 1 1 0 PHD-finger Pkinase PF00069.25 CBK21849.2 - 5.2e-72 242.4 0.0 6.4e-72 242.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBK21849.2 - 2.1e-31 109.2 0.0 3.5e-31 108.4 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 CBK21849.2 - 0.00098 18.5 0.1 0.0021 17.5 0.1 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CBK21849.2 - 0.0024 17.8 0.0 0.0048 16.8 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 CBK21849.2 - 0.0032 16.8 0.0 0.0047 16.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 CBK21849.2 - 0.02 13.7 0.0 0.03 13.1 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase CC2D2AN-C2 PF15625.6 CBK21849.2 - 0.087 12.6 0.0 0.15 11.8 0.0 1.3 1 0 0 1 1 1 0 CC2D2A N-terminal C2 domain NTP_transferase PF00483.23 CBK21850.2 - 1.3e-46 159.2 0.0 1.6e-46 158.9 0.0 1.1 1 0 0 1 1 1 1 Nucleotidyl transferase Hexapep PF00132.24 CBK21850.2 - 2.2e-10 39.8 2.9 2.3e-07 30.3 1.2 2.7 1 1 1 2 2 2 2 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.7 CBK21850.2 - 8.3e-07 29.5 0.0 1.2e-06 29.0 0.0 1.3 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep_2 PF14602.6 CBK21850.2 - 7.2e-06 25.7 6.8 1.4e-05 24.8 2.0 2.9 1 1 1 2 2 2 1 Hexapeptide repeat of succinyl-transferase DUF4954 PF16314.5 CBK21850.2 - 0.022 12.9 0.1 0.032 12.4 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4954) Fucokinase PF07959.12 CBK21850.2 - 0.03 13.3 0.1 0.067 12.1 0.0 1.6 2 0 0 2 2 2 0 L-fucokinase Aminotran_1_2 PF00155.21 CBK21851.2 - 1.4e-37 129.8 0.0 1.8e-37 129.4 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 CBK21851.2 - 0.017 14.4 0.0 0.041 13.2 0.0 1.7 2 0 0 2 2 2 0 Beta-eliminating lyase DUF563 PF04577.14 CBK21852.2 - 3.9e-16 59.8 0.0 4.7e-16 59.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF563) Aldedh PF00171.22 CBK21853.2 - 1.6e-79 267.6 0.0 1.8e-79 267.4 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family zf-UBP_var PF17807.1 CBK21853.2 - 0.03 14.1 3.0 0.47 10.2 0.2 2.6 1 1 1 2 2 2 0 Variant UBP zinc finger DDE_Tnp_ISL3 PF01610.17 CBK21853.2 - 0.079 12.7 0.1 0.13 11.9 0.1 1.3 1 0 0 1 1 1 0 Transposase mRNA_cap_enzyme PF01331.19 CBK21854.2 - 3e-48 164.2 0.1 6.1e-48 163.2 0.1 1.5 2 0 0 2 2 2 1 mRNA capping enzyme, catalytic domain DNA_ligase_A_M PF01068.21 CBK21854.2 - 8.2e-08 32.1 0.0 0.00017 21.3 0.0 2.1 1 1 1 2 2 2 2 ATP dependent DNA ligase domain Pox_ATPase-GT PF10640.9 CBK21854.2 - 0.1 11.5 0.1 0.33 9.8 0.0 1.8 2 0 0 2 2 2 0 mRNA capping enzyme N-terminal, ATPase and guanylyltransferase Mur_ligase_M PF08245.12 CBK21855.2 - 2.1e-07 31.1 0.0 0.00072 19.6 0.0 2.0 2 0 0 2 2 2 2 Mur ligase middle domain AhpC-TSA PF00578.21 CBK21857.2 - 8.1e-36 122.7 0.0 1.1e-35 122.3 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family 1-cysPrx_C PF10417.9 CBK21857.2 - 2.3e-12 46.5 0.0 4.8e-12 45.5 0.0 1.5 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin Redoxin PF08534.10 CBK21857.2 - 1.2e-11 44.6 0.0 1.5e-11 44.2 0.0 1.1 1 0 0 1 1 1 1 Redoxin Pkinase PF00069.25 CBK21858.2 - 1.2e-13 51.1 0.1 1.3e-13 51.0 0.1 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBK21858.2 - 1.8e-06 27.4 0.0 2.1e-06 27.2 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 CBK21859.2 - 1.3e-18 67.3 0.0 2.8e-18 66.2 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBK21859.2 - 2e-12 47.0 0.0 5.3e-12 45.6 0.0 1.7 1 0 0 1 1 1 1 Protein tyrosine kinase DUF4644 PF15486.6 CBK21859.2 - 2.3 7.9 4.6 0.59 9.9 0.8 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4644) HECT PF00632.25 CBK21860.2 - 2.6e-63 214.3 0.0 6.3e-63 213.1 0.0 1.7 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) MIB_HERC2 PF06701.13 CBK21861.2 - 5.9e-19 68.1 7.9 8e-19 67.7 7.9 1.2 1 0 0 1 1 1 1 Mib_herc2 DUF1580 PF07618.11 CBK21862.2 - 0.2 11.3 0.0 30 4.3 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1580) AhpC-TSA PF00578.21 CBK21864.2 - 8e-36 122.7 0.0 1.1e-35 122.3 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 CBK21864.2 - 1.2e-11 44.6 0.0 1.5e-11 44.2 0.0 1.1 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.9 CBK21864.2 - 1.8e-11 43.7 0.0 3.8e-11 42.6 0.0 1.5 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin DNA_pol_B_2 PF03175.13 CBK21865.2 - 1.4e-17 63.8 12.3 5.1e-15 55.3 8.3 2.4 2 0 0 2 2 2 2 DNA polymerase type B, organellar and viral NinG PF05766.12 CBK21865.2 - 0.18 11.7 2.4 0.36 10.8 2.4 1.4 1 0 0 1 1 1 0 Bacteriophage Lambda NinG protein AhpC-TSA PF00578.21 CBK21867.2 - 8e-36 122.7 0.0 1.1e-35 122.3 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 CBK21867.2 - 1.2e-11 44.6 0.0 1.5e-11 44.2 0.0 1.1 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.9 CBK21867.2 - 1.8e-11 43.7 0.0 3.8e-11 42.6 0.0 1.5 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin Mo25 PF08569.11 CBK21868.2 - 8.3e-40 137.1 5.8 1.4e-39 136.4 5.8 1.3 1 1 0 1 1 1 1 Mo25-like V-ATPase_H_N PF03224.14 CBK21868.2 - 0.018 14.4 0.2 0.019 14.3 0.2 1.2 1 0 0 1 1 1 0 V-ATPase subunit H XPC-binding PF09280.11 CBK21868.2 - 0.13 12.0 0.2 19 5.1 0.0 2.6 2 0 0 2 2 2 0 XPC-binding domain DUF3858 PF12970.7 CBK21870.2 - 0.092 12.8 1.6 0.21 11.6 1.6 1.6 1 0 0 1 1 1 0 Domain of Unknown Function with PDB structure (DUF3858) CorA PF01544.18 CBK21870.2 - 1.8 7.8 15.8 0.035 13.4 6.7 2.5 2 1 1 3 3 3 0 CorA-like Mg2+ transporter protein DUF4140 PF13600.6 CBK21870.2 - 3.6 8.1 12.2 0.69 10.4 0.9 3.1 3 1 0 3 3 3 0 N-terminal domain of unknown function (DUF4140) Nfu_N PF08712.11 CBK21871.2 - 5.4e-26 90.5 0.3 2.2e-25 88.5 0.0 2.1 2 0 0 2 2 2 1 Scaffold protein Nfu/NifU N terminal NifU PF01106.17 CBK21871.2 - 2.4e-25 88.5 0.0 4.7e-25 87.5 0.0 1.5 1 0 0 1 1 1 1 NifU-like domain FPL PF09758.9 CBK21873.2 - 5.1e-43 146.6 7.3 6.4e-43 146.3 7.3 1.1 1 0 0 1 1 1 1 Uncharacterised conserved protein HHV-1_VABD PF16852.5 CBK21873.2 - 0.041 13.9 1.0 8.2 6.5 0.3 2.5 2 0 0 2 2 2 0 Herpes viral adaptor-to-host cellular mRNA binding domain RIX1 PF08167.12 CBK21873.2 - 0.16 11.7 1.2 0.24 11.1 1.2 1.3 1 0 0 1 1 1 0 rRNA processing/ribosome biogenesis RPEL PF02755.15 CBK21874.2 - 0.00018 21.1 5.4 0.0023 17.6 0.5 3.7 4 0 0 4 4 4 1 RPEL repeat CFAP91 PF14738.6 CBK21874.2 - 0.65 10.0 5.7 0.61 10.1 0.2 2.5 1 1 0 2 2 2 0 Cilia- and flagella-associated protein 91 ER PF01133.17 CBK21876.2 - 1.6e-28 98.6 0.1 2.5e-28 98.0 0.1 1.2 1 0 0 1 1 1 1 Enhancer of rudimentary PTPA PF03095.15 CBK21877.2 - 2.4e-73 247.2 0.0 2.9e-73 246.9 0.0 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein S6PP_C PF08472.10 CBK21877.2 - 0.19 11.6 0.0 0.35 10.7 0.0 1.4 1 0 0 1 1 1 0 Sucrose-6-phosphate phosphohydrolase C-terminal Syntaxin-6_N PF09177.11 CBK21878.2 - 2.8e-14 53.5 1.1 2.8e-14 53.5 1.1 2.3 2 1 0 2 2 2 1 Syntaxin 6, N-terminal SNARE PF05739.19 CBK21878.2 - 3.5e-08 33.3 0.7 1.2e-07 31.6 0.7 2.0 1 0 0 1 1 1 1 SNARE domain T3SSipB PF16535.5 CBK21878.2 - 0.0013 19.2 12.7 0.056 13.9 3.3 2.8 1 1 1 2 2 2 2 Type III cell invasion protein SipB DUF2207 PF09972.9 CBK21878.2 - 0.0095 14.8 0.7 0.0095 14.8 0.7 2.1 2 0 0 2 2 2 1 Predicted membrane protein (DUF2207) ActA PF05058.12 CBK21878.2 - 0.018 13.4 2.5 0.023 13.1 2.5 1.1 1 0 0 1 1 1 0 ActA Protein FlaC_arch PF05377.11 CBK21878.2 - 0.027 14.9 3.6 8.5 6.9 0.1 3.7 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) ATG16 PF08614.11 CBK21878.2 - 0.07 13.4 16.7 0.7 10.1 0.6 2.1 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) Lzipper-MIP1 PF14389.6 CBK21878.2 - 0.12 12.7 1.5 0.22 11.9 0.1 2.2 2 0 0 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 Cep57_CLD_2 PF14197.6 CBK21878.2 - 0.26 11.4 0.2 0.26 11.4 0.2 3.6 3 1 0 3 3 2 0 Centrosome localisation domain of PPC89 DUF4407 PF14362.6 CBK21878.2 - 0.28 10.5 12.4 1.3 8.3 3.1 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) Baculo_PEP_C PF04513.12 CBK21878.2 - 0.29 11.2 2.9 5.1 7.1 0.1 2.4 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF16 PF01519.16 CBK21878.2 - 0.33 11.5 6.7 6.5 7.3 2.2 2.7 2 1 0 2 2 2 0 Protein of unknown function DUF16 GTP-bdg_M PF16360.5 CBK21878.2 - 0.33 11.6 3.1 7.2 7.3 0.0 3.2 3 0 0 3 3 3 0 GTP-binding GTPase Middle Region EMP24_GP25L PF01105.24 CBK21878.2 - 0.56 10.1 4.5 0.54 10.2 1.2 2.3 2 1 0 2 2 2 0 emp24/gp25L/p24 family/GOLD TBCA PF02970.16 CBK21878.2 - 0.6 10.5 9.5 0.21 11.9 3.2 2.8 1 1 1 3 3 3 0 Tubulin binding cofactor A Lebercilin PF15619.6 CBK21878.2 - 1.5 8.4 13.6 3.1 7.4 0.8 2.5 1 1 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease bZIP_1 PF00170.21 CBK21878.2 - 1.7 8.8 7.9 1.1 9.4 0.2 3.4 2 1 0 3 3 3 0 bZIP transcription factor CCDC-167 PF15188.6 CBK21878.2 - 1.9 8.9 8.7 4.7 7.6 1.5 3.1 2 2 0 2 2 2 0 Coiled-coil domain-containing protein 167 CREPT PF16566.5 CBK21878.2 - 7.8 6.7 11.9 5 7.3 4.2 2.5 1 1 0 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour SlyX PF04102.12 CBK21878.2 - 8 7.2 6.9 26 5.5 1.3 3.2 2 2 2 4 4 4 0 SlyX MMS19_N PF14500.6 CBK21880.2 - 2.9e-28 99.2 0.1 4.7e-28 98.5 0.1 1.3 1 0 0 1 1 1 1 Dos2-interacting transcription regulator of RNA-Pol-II HEAT PF02985.22 CBK21880.2 - 5.2e-05 23.2 0.1 0.12 12.7 0.0 3.8 3 0 0 3 3 3 2 HEAT repeat HEAT_2 PF13646.6 CBK21880.2 - 0.0015 18.8 0.0 0.21 12.0 0.0 2.9 2 0 0 2 2 2 1 HEAT repeats Cnd1 PF12717.7 CBK21880.2 - 0.048 13.7 0.0 5 7.1 0.0 2.5 2 0 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 CBK21880.2 - 0.11 11.1 0.1 2.1 6.8 0.0 2.3 2 0 0 2 2 2 0 Adaptin N terminal region Nuc_sug_transp PF04142.15 CBK21881.2 - 1.5e-28 99.9 16.1 2.3e-28 99.3 16.1 1.2 1 0 0 1 1 1 1 Nucleotide-sugar transporter EamA PF00892.20 CBK21881.2 - 0.019 15.1 23.0 0.12 12.5 6.8 2.2 2 0 0 2 2 2 0 EamA-like transporter family Lactamase_B PF00753.27 CBK21882.2 - 0.015 15.3 0.0 0.023 14.7 0.0 1.3 1 0 0 1 1 1 0 Metallo-beta-lactamase superfamily Zip PF02535.22 CBK21883.2 - 1.1e-06 28.2 4.9 0.004 16.4 0.1 2.1 1 1 1 2 2 2 2 ZIP Zinc transporter Zip PF02535.22 CBK21884.2 - 4.4e-20 72.2 1.6 5.6e-20 71.8 1.6 1.1 1 0 0 1 1 1 1 ZIP Zinc transporter E1-E2_ATPase PF00122.20 CBK21884.2 - 0.0012 18.4 0.1 0.0022 17.5 0.1 1.5 1 0 0 1 1 1 1 E1-E2 ATPase Peroxin-3 PF04882.12 CBK21884.2 - 0.073 12.1 0.3 0.093 11.7 0.3 1.1 1 0 0 1 1 1 0 Peroxin-3 Zip PF02535.22 CBK21885.2 - 7.8e-19 68.1 0.5 8.9e-19 67.9 0.5 1.1 1 0 0 1 1 1 1 ZIP Zinc transporter E1-E2_ATPase PF00122.20 CBK21885.2 - 0.0011 18.6 0.2 0.0017 17.9 0.2 1.4 1 0 0 1 1 1 1 E1-E2 ATPase Peroxin-3 PF04882.12 CBK21885.2 - 0.054 12.5 0.3 0.066 12.2 0.3 1.1 1 0 0 1 1 1 0 Peroxin-3 Zip PF02535.22 CBK21886.2 - 6.5e-07 28.9 6.3 4.9e-05 22.7 0.8 2.2 1 1 1 2 2 2 2 ZIP Zinc transporter Ribosomal_L11 PF00298.19 CBK21887.2 - 8.5e-26 90.3 0.1 1.3e-25 89.7 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain Ribosomal_L11_N PF03946.14 CBK21887.2 - 1.5e-20 72.7 0.0 2.9e-20 71.9 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain CUTL PF16557.5 CBK21887.2 - 0.022 15.0 0.3 0.038 14.2 0.3 1.4 1 0 0 1 1 1 0 CUT1-like DNA-binding domain of SATB Ras PF00071.22 CBK21888.2 - 7.6e-50 168.7 0.0 8.8e-50 168.5 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CBK21888.2 - 9.5e-18 64.6 0.0 1.4e-17 64.0 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CBK21888.2 - 2e-05 24.1 0.0 2.8e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Helicase_C PF00271.31 CBK21889.2 - 9e-16 58.2 0.0 2.6e-15 56.7 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain RecQ_Zn_bind PF16124.5 CBK21889.2 - 4.3e-12 46.6 1.5 8.5e-12 45.6 1.5 1.5 1 0 0 1 1 1 1 RecQ zinc-binding DEAD PF00270.29 CBK21889.2 - 0.00053 19.8 0.0 0.00089 19.1 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF3052 PF11253.8 CBK21889.2 - 0.002 18.1 0.0 0.0036 17.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3052) XG_FTase PF03254.13 CBK21890.2 - 1e-06 27.7 0.5 0.0004 19.1 0.1 2.7 2 1 1 3 3 3 2 Xyloglucan fucosyltransferase NodZ PF05830.11 CBK21890.2 - 0.00022 20.1 0.0 0.00033 19.6 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein Z (NodZ) O-FucT PF10250.9 CBK21890.2 - 0.00024 20.9 0.0 0.00038 20.3 0.0 1.4 1 0 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase Phospholip_B PF04916.13 CBK21891.2 - 3.5e-126 421.9 0.3 4.3e-126 421.6 0.3 1.0 1 0 0 1 1 1 1 Phospholipase B AAA PF00004.29 CBK21891.2 - 2.2e-34 118.7 0.0 3.8e-34 118.0 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 CBK21891.2 - 9.4e-06 26.1 2.4 0.00037 20.9 2.4 2.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 CBK21891.2 - 0.00029 21.1 0.3 0.0051 17.1 0.3 2.3 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.14 CBK21891.2 - 0.0014 18.6 0.0 0.035 14.1 0.0 2.4 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_24 PF13479.6 CBK21891.2 - 0.0087 15.8 0.0 0.044 13.5 0.0 2.0 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 CBK21891.2 - 0.011 15.6 0.4 0.53 10.2 0.2 2.5 2 1 0 2 2 1 0 NACHT domain DUF815 PF05673.13 CBK21891.2 - 0.013 14.6 0.0 0.024 13.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) RuvB_N PF05496.12 CBK21891.2 - 0.03 14.1 0.0 0.064 13.0 0.0 1.5 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_28 PF13521.6 CBK21891.2 - 0.054 13.7 0.0 0.14 12.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 CBK21891.2 - 0.064 13.8 0.0 0.25 11.9 0.0 2.0 2 0 0 2 2 1 0 AAA domain AAA_11 PF13086.6 CBK21891.2 - 0.15 11.8 0.0 0.25 11.1 0.0 1.2 1 0 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 CBK21891.2 - 0.17 11.8 0.0 0.74 9.7 0.0 1.9 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea AAA_7 PF12775.7 CBK21891.2 - 0.17 11.4 0.0 0.55 9.7 0.0 1.7 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_25 PF13481.6 CBK21891.2 - 0.19 11.3 0.2 0.91 9.1 0.0 2.0 2 0 0 2 2 2 0 AAA domain Glyco_transf_49 PF13896.6 CBK21893.2 - 1.9e-21 76.8 1.0 5e-21 75.4 1.0 1.5 1 1 0 1 1 1 1 Glycosyl-transferase for dystroglycan NOA36 PF06524.12 CBK21894.2 - 3.1e-86 289.5 46.0 4e-86 289.1 46.0 1.0 1 0 0 1 1 1 1 NOA36 protein HA2 PF04408.23 CBK21895.2 - 3.5e-24 85.2 0.0 8.7e-24 83.9 0.0 1.7 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 CBK21895.2 - 3.3e-18 65.8 0.0 7.8e-18 64.6 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 CBK21895.2 - 3.2e-10 40.3 0.0 6.7e-10 39.3 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 CBK21895.2 - 7.9e-09 35.5 0.2 1.7e-08 34.5 0.2 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 CBK21895.2 - 7.1e-05 23.1 0.1 0.0002 21.6 0.1 1.7 1 0 0 1 1 1 1 AAA domain ResIII PF04851.15 CBK21895.2 - 0.00028 20.9 0.1 0.0061 16.6 0.1 2.3 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 CBK21895.2 - 0.00036 20.9 0.5 0.00078 19.8 0.1 1.7 2 0 0 2 2 2 1 AAA domain DUF2075 PF09848.9 CBK21895.2 - 0.0094 15.2 0.0 0.017 14.4 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_30 PF13604.6 CBK21895.2 - 0.013 15.2 0.0 0.024 14.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain T2SSE PF00437.20 CBK21895.2 - 0.015 14.4 0.0 0.026 13.6 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein SRP54 PF00448.22 CBK21895.2 - 0.018 14.7 0.0 0.043 13.4 0.0 1.6 1 1 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_14 PF13173.6 CBK21895.2 - 0.12 12.4 0.0 1.8 8.6 0.0 2.4 1 1 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.18 CBK21895.2 - 0.13 11.6 0.0 0.22 10.8 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family SDP_N PF12278.8 CBK21895.2 - 1.8 8.7 4.6 3.5 7.8 4.6 1.5 1 0 0 1 1 1 0 Sex determination protein N terminal T3SSipB PF16535.5 CBK21896.2 - 0.00036 21.0 15.6 0.03 14.8 0.6 3.3 2 1 1 3 3 3 2 Type III cell invasion protein SipB Tropomyosin_1 PF12718.7 CBK21896.2 - 0.00044 20.4 14.6 0.00044 20.4 14.6 4.3 3 1 1 4 4 4 1 Tropomyosin like ZapB PF06005.12 CBK21896.2 - 0.0013 19.1 5.1 0.0013 19.1 5.1 6.0 2 2 4 6 6 5 3 Cell division protein ZapB CENP-F_leu_zip PF10473.9 CBK21896.2 - 0.0024 17.9 15.4 0.0024 17.9 15.4 4.6 2 1 2 4 4 4 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Nup54 PF13874.6 CBK21896.2 - 0.0038 17.3 10.9 0.0038 17.3 10.9 3.6 2 1 1 3 3 3 1 Nucleoporin complex subunit 54 DUF3450 PF11932.8 CBK21896.2 - 0.011 15.0 8.2 0.011 15.0 8.2 4.9 3 1 2 5 5 5 0 Protein of unknown function (DUF3450) DUF1664 PF07889.12 CBK21896.2 - 0.015 15.4 6.1 0.015 15.4 6.1 3.4 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) DivIC PF04977.15 CBK21896.2 - 0.023 14.4 2.4 0.023 14.4 2.4 5.6 3 2 2 5 5 5 0 Septum formation initiator YabA PF06156.13 CBK21896.2 - 0.028 15.0 36.2 0.17 12.5 3.2 4.7 2 2 2 4 4 4 0 Initiation control protein YabA Filament PF00038.21 CBK21896.2 - 0.031 13.9 39.9 0.47 10.0 3.2 2.8 2 1 0 2 2 2 0 Intermediate filament protein Spc7 PF08317.11 CBK21896.2 - 0.089 11.7 47.4 0.012 14.6 21.0 3.2 2 1 1 3 3 3 0 Spc7 kinetochore protein DUF2746 PF10874.8 CBK21896.2 - 0.1 13.0 1.6 21 5.6 0.2 3.1 2 1 0 2 2 2 0 Protein of unknown function (DUF2746) LAM_C PF12544.8 CBK21896.2 - 0.48 10.6 7.4 0.26 11.5 3.9 2.3 1 1 0 1 1 1 0 Lysine-2,3-aminomutase Golgin_A5 PF09787.9 CBK21896.2 - 0.5 9.8 45.5 0.26 10.7 5.3 3.3 2 1 1 3 3 3 0 Golgin subfamily A member 5 CtIP_N PF10482.9 CBK21896.2 - 0.98 9.5 32.2 0.11 12.5 0.3 3.6 3 2 0 3 3 3 0 Tumour-suppressor protein CtIP N-terminal domain Fez1 PF06818.15 CBK21896.2 - 1.3 9.4 41.5 0.52 10.7 14.8 3.4 2 1 1 3 3 3 0 Fez1 HOOK PF05622.12 CBK21896.2 - 1.5 6.9 46.4 0.37 8.9 11.1 3.5 2 1 2 4 4 4 0 HOOK protein DUF2730 PF10805.8 CBK21896.2 - 2.4 8.3 18.2 0.24 11.5 1.1 3.7 2 1 1 3 3 3 0 Protein of unknown function (DUF2730) MbeD_MobD PF04899.12 CBK21896.2 - 3.1 8.0 13.4 0.036 14.2 3.8 2.8 3 0 0 3 3 3 0 MbeD/MobD like bZIP_1 PF00170.21 CBK21896.2 - 4.3 7.5 38.5 0.15 12.2 2.1 5.8 4 2 2 6 6 6 0 bZIP transcription factor GAS PF13851.6 CBK21896.2 - 5.1 6.4 49.0 0.06 12.7 20.4 4.4 2 2 3 5 5 5 0 Growth-arrest specific micro-tubule binding Atg14 PF10186.9 CBK21896.2 - 5.7 5.9 37.1 1.5 7.8 11.1 3.4 2 1 1 3 3 3 0 Vacuolar sorting 38 and autophagy-related subunit 14 Leu_zip PF15294.6 CBK21896.2 - 7.2 6.0 44.4 0.15 11.6 23.9 3.8 3 1 0 3 3 3 0 Leucine zipper DUF948 PF06103.11 CBK21896.2 - 8.1 6.8 9.3 6.4 7.1 4.6 3.0 2 1 2 4 4 3 0 Bacterial protein of unknown function (DUF948) potato_inhibit PF00280.18 CBK21898.2 - 3.3e-20 72.5 0.3 4.5e-20 72.1 0.3 1.2 1 0 0 1 1 1 1 Potato inhibitor I family Fungus-induced PF10917.8 CBK21898.2 - 0.03 14.6 0.1 0.054 13.8 0.1 1.4 1 0 0 1 1 1 0 Fungus-induced protein Ribosomal_L36 PF00444.18 CBK21898.2 - 0.074 13.3 0.3 0.14 12.4 0.3 1.6 1 1 0 1 1 1 0 Ribosomal protein L36 DIM PF08194.12 CBK21898.2 - 0.53 10.5 0.1 0.53 10.5 0.1 1.9 2 0 0 2 2 2 0 DIM protein Ribosomal_L18 PF17135.4 CBK21900.2 - 2.4e-90 301.0 0.5 2.6e-90 300.8 0.5 1.0 1 0 0 1 1 1 1 Ribosomal protein 60S L18 and 50S L18e Ribosomal_L27A PF00828.19 CBK21900.2 - 0.00074 20.2 1.2 0.0014 19.3 0.0 2.1 2 1 0 2 2 2 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A OprF PF05736.11 CBK21900.2 - 0.14 11.8 0.0 0.28 10.9 0.0 1.4 1 1 0 1 1 1 0 OprF membrane domain Sec7 PF01369.20 CBK21901.2 - 4e-22 78.8 0.6 7.6e-22 77.9 0.6 1.5 1 0 0 1 1 1 1 Sec7 domain CDC37_C PF08564.10 CBK21901.2 - 0.13 12.4 0.2 0.24 11.5 0.2 1.4 1 0 0 1 1 1 0 Cdc37 C terminal domain Ribosomal_60s PF00428.19 CBK21902.2 - 2.3e-21 76.2 19.1 2.6e-21 76.0 19.1 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein DUF3824 PF12868.7 CBK21902.2 - 0.095 13.4 2.2 0.13 12.9 2.2 1.1 1 0 0 1 1 1 0 Domain of unknwon function (DUF3824) Myc_N PF01056.18 CBK21902.2 - 0.5 10.2 2.4 0.5 10.2 2.4 1.2 1 0 0 1 1 1 0 Myc amino-terminal region RNA_pol_3_Rpc31 PF11705.8 CBK21902.2 - 1.5 9.1 8.5 1.8 8.8 8.5 1.1 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Thioredoxin_6 PF13848.6 CBK21903.2 - 6.1e-08 32.8 0.0 2.1e-05 24.5 0.0 2.1 1 1 1 2 2 2 2 Thioredoxin-like domain Thioredoxin PF00085.20 CBK21903.2 - 0.0008 19.4 0.0 0.0014 18.6 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin PHD PF00628.29 CBK21904.2 - 3.2e-05 23.7 11.8 3.2e-05 23.7 11.8 3.3 3 1 0 3 3 3 1 PHD-finger GAGA PF09237.11 CBK21904.2 - 0.00016 21.4 0.5 0.00016 21.4 0.5 2.1 2 0 0 2 2 2 1 GAGA factor zf-met PF12874.7 CBK21904.2 - 0.00019 21.7 1.0 0.059 13.8 0.3 3.1 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-Di19 PF05605.12 CBK21904.2 - 0.0003 21.0 2.8 0.0003 21.0 2.8 3.6 3 0 0 3 3 3 1 Drought induced 19 protein (Di19), zinc-binding PHD_2 PF13831.6 CBK21904.2 - 0.14 11.7 7.4 0.056 13.0 3.9 2.3 2 0 0 2 2 2 0 PHD-finger Elf1 PF05129.13 CBK21904.2 - 0.16 12.1 0.2 0.16 12.1 0.2 3.1 2 1 1 3 3 3 0 Transcription elongation factor Elf1 like Rad50_zn_hook PF04423.14 CBK21904.2 - 0.16 11.8 3.2 1.8 8.5 0.4 2.8 2 0 0 2 2 2 0 Rad50 zinc hook motif zf-BED PF02892.15 CBK21904.2 - 0.49 10.5 5.2 0.46 10.5 0.4 2.8 2 0 0 2 2 2 0 BED zinc finger Cys_rich_KTR PF14205.6 CBK21904.2 - 0.55 10.1 10.6 0.19 11.6 1.2 3.1 3 0 0 3 3 3 0 Cysteine-rich KTR Forkhead_N PF08430.12 CBK21904.2 - 2.9 8.5 65.8 51 4.5 65.8 2.3 1 1 0 1 1 1 0 Forkhead N-terminal region Rhomboid PF01694.22 CBK21905.2 - 4e-15 56.1 7.7 8.6e-14 51.8 7.7 2.0 1 1 0 1 1 1 1 Rhomboid family Ist1 PF03398.14 CBK21907.2 - 2.7e-19 69.7 0.1 3.5e-19 69.3 0.1 1.1 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway Peptidase_M24 PF00557.24 CBK21908.2 - 2.8e-36 125.2 0.0 3.8e-36 124.8 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 TPR_14 PF13428.6 CBK21910.2 - 0.004 17.9 0.1 9.1 7.4 0.0 4.3 2 1 3 5 5 5 1 Tetratricopeptide repeat TPR_2 PF07719.17 CBK21910.2 - 0.0055 16.7 0.1 7.7 6.9 0.0 4.8 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_1 PF00515.28 CBK21910.2 - 0.07 13.0 0.2 12 6.0 0.0 4.0 5 0 0 5 5 5 0 Tetratricopeptide repeat Phlebovirus_G1 PF07243.11 CBK21910.2 - 0.11 10.8 0.1 0.14 10.5 0.1 1.1 1 0 0 1 1 1 0 Phlebovirus glycoprotein G1 VWA_2 PF13519.6 CBK21911.2 - 0.0076 16.9 0.0 0.028 15.1 0.0 1.9 2 0 0 2 2 2 1 von Willebrand factor type A domain P21-Arc PF04062.14 CBK21912.2 - 5.4e-52 176.3 0.1 6.6e-52 176.1 0.1 1.1 1 0 0 1 1 1 1 ARP2/3 complex ARPC3 (21 kDa) subunit Cyclin_N PF00134.23 CBK21913.2 - 4.5e-14 52.3 0.6 6.3e-14 51.8 0.6 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 CBK21913.2 - 0.002 18.2 0.2 0.002 18.2 0.2 2.2 2 1 0 2 2 2 1 Cyclin, C-terminal domain PCI PF01399.27 CBK21914.2 - 5.9e-13 49.2 0.9 2.5e-12 47.2 0.0 2.5 3 0 0 3 3 3 1 PCI domain CSN8_PSD8_EIF3K PF10075.9 CBK21914.2 - 2.9e-05 24.1 0.1 0.00014 21.9 0.0 2.0 2 0 0 2 2 2 1 CSN8/PSMD8/EIF3K family DHHC PF01529.20 CBK21915.2 - 3.3e-13 49.9 4.8 4.1e-13 49.6 4.8 1.2 1 0 0 1 1 1 1 DHHC palmitoyltransferase DUF1885 PF08968.10 CBK21915.2 - 0.24 11.5 0.0 0.25 11.4 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1885) Acetyltransf_3 PF13302.7 CBK21916.2 - 1.6e-31 109.8 0.0 1.9e-31 109.5 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 CBK21916.2 - 9.7e-08 32.3 0.1 1.4e-07 31.8 0.1 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family DUF2824 PF11039.8 CBK21916.2 - 0.086 12.8 0.0 0.12 12.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2824) SMK-1 PF04802.15 CBK21917.2 - 9e-37 126.8 3.3 1.2e-36 126.3 1.4 2.1 2 0 0 2 2 2 1 Component of IIS longevity pathway SMK-1 FUR PF01475.19 CBK21917.2 - 0.09 12.9 0.1 0.3 11.2 0.1 1.9 1 1 0 1 1 1 0 Ferric uptake regulator family GAT PF03127.14 CBK21917.2 - 0.46 10.8 3.7 15 6.0 0.1 2.8 3 0 0 3 3 3 0 GAT domain Aa_trans PF01490.18 CBK21918.2 - 4.4e-35 121.2 22.6 5.2e-35 120.9 22.6 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Bromodomain PF00439.25 CBK21919.2 - 1.1e-16 60.6 0.0 3.1e-16 59.2 0.0 1.6 1 0 0 1 1 1 1 Bromodomain SH3_1 PF00018.28 CBK21919.2 - 0.0014 18.2 0.0 0.0026 17.3 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 CBK21919.2 - 0.0038 17.1 0.1 0.01 15.7 0.0 1.8 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.17 CBK21919.2 - 0.0077 15.9 0.0 0.018 14.7 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain Acetyltransf_1 PF00583.25 CBK21920.2 - 3.3e-11 43.5 0.0 5.4e-11 42.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 CBK21920.2 - 8.8e-06 25.7 0.0 1.8e-05 24.7 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 CBK21920.2 - 0.0023 18.3 0.0 0.0044 17.4 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 CBK21920.2 - 0.057 13.4 0.0 0.12 12.4 0.0 1.5 1 0 0 1 1 1 0 FR47-like protein PEHE PF15275.6 CBK21920.2 - 8.6 7.0 7.6 2.2 8.9 2.5 2.0 1 1 1 2 2 2 0 PEHE domain Acetyltransf_1 PF00583.25 CBK21921.2 - 1.6e-15 57.3 0.2 2.6e-14 53.4 0.0 2.5 2 1 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 CBK21921.2 - 3.2e-13 49.7 0.1 4.3e-11 42.8 0.0 2.4 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 CBK21921.2 - 8.8e-12 45.3 0.6 1.6e-09 38.1 0.1 2.4 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain FR47 PF08445.10 CBK21921.2 - 1.1e-08 34.9 0.0 1.1e-05 25.4 0.0 2.4 2 0 0 2 2 2 2 FR47-like protein Acetyltransf_4 PF13420.7 CBK21921.2 - 0.0015 18.7 4.8 0.0045 17.1 0.3 2.5 3 0 0 3 3 3 1 Acetyltransferase (GNAT) domain NMT PF01233.19 CBK21921.2 - 0.017 15.0 0.0 0.029 14.2 0.0 1.4 1 0 0 1 1 1 0 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain RRM_1 PF00076.22 CBK21922.2 - 2e-06 27.5 0.0 5.8e-06 26.0 0.0 1.7 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CBK21922.2 - 0.013 15.6 0.0 0.032 14.4 0.0 1.7 1 0 0 1 1 1 0 RNA recognition motif YccJ PF13993.6 CBK21922.2 - 0.051 13.9 1.5 0.16 12.4 1.5 1.8 1 0 0 1 1 1 0 YccJ-like protein Kinesin PF00225.23 CBK21924.2 - 2.7e-99 332.3 0.9 3.1e-99 332.1 0.9 1.0 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 CBK21924.2 - 3e-23 82.4 1.0 4.9e-21 75.2 0.0 2.2 2 0 0 2 2 2 2 Microtubule binding SSF PF00474.17 CBK21925.2 - 4.2e-26 91.7 27.5 4.2e-26 91.7 27.5 2.3 2 1 0 2 2 2 1 Sodium:solute symporter family UPF0093 PF03653.13 CBK21925.2 - 0.094 12.9 0.1 0.094 12.9 0.1 3.9 4 1 0 4 4 4 0 Uncharacterised protein family (UPF0093) PNP_UDP_1 PF01048.20 CBK21926.2 - 1.3e-24 86.8 0.0 1.5e-24 86.6 0.0 1.0 1 0 0 1 1 1 1 Phosphorylase superfamily Folate_carrier PF01770.18 CBK21927.2 - 0.48 9.1 1.1 0.91 8.2 1.1 1.4 1 0 0 1 1 1 0 Reduced folate carrier SGS PF05002.15 CBK21928.2 - 1.1e-17 63.9 1.6 1.9e-17 63.2 1.6 1.5 1 1 0 1 1 1 1 SGS domain CS PF04969.16 CBK21928.2 - 1.8e-09 38.5 0.0 3.5e-09 37.6 0.0 1.5 1 0 0 1 1 1 1 CS domain DUF1554 PF07588.11 CBK21928.2 - 0.066 13.0 0.1 0.18 11.6 0.0 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1554) CRAL_TRIO_2 PF13716.6 CBK21928.2 - 0.12 12.6 0.0 0.18 12.0 0.0 1.5 1 0 0 1 1 1 0 Divergent CRAL/TRIO domain XG_FTase PF03254.13 CBK21929.2 - 0.0032 16.2 0.0 0.0037 16.0 0.0 1.1 1 0 0 1 1 1 1 Xyloglucan fucosyltransferase zf-RING_2 PF13639.6 CBK21931.2 - 9.2e-13 48.3 6.8 2.5e-12 46.9 6.8 1.8 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 CBK21931.2 - 1.2e-09 37.7 4.9 3.8e-09 36.1 4.9 1.9 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_5 PF14634.6 CBK21931.2 - 1.5e-09 37.7 5.0 4.5e-09 36.1 5.0 1.9 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 CBK21931.2 - 1.5e-08 34.3 6.1 3.5e-08 33.2 6.1 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CBK21931.2 - 7.3e-08 32.2 5.7 2.2e-07 30.7 5.7 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 CBK21931.2 - 2.4e-07 30.9 7.1 1.4e-06 28.5 7.1 2.2 1 1 0 1 1 1 1 RING-H2 zinc finger domain PA PF02225.22 CBK21931.2 - 2.2e-06 27.6 0.0 4.9e-06 26.5 0.0 1.5 1 0 0 1 1 1 1 PA domain Zn_ribbon_17 PF17120.5 CBK21931.2 - 2.7e-06 26.9 2.9 6.6e-06 25.7 2.9 1.6 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-ANAPC11 PF12861.7 CBK21931.2 - 6.8e-06 26.1 0.9 2.4e-05 24.3 0.9 2.0 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.6 CBK21931.2 - 1.7e-05 24.6 2.6 4.5e-05 23.2 2.6 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CBK21931.2 - 1.9e-05 24.6 2.8 9.4e-05 22.4 1.0 2.7 1 1 1 2 2 2 1 RING-type zinc-finger Prok-RING_4 PF14447.6 CBK21931.2 - 0.0034 17.2 4.0 0.011 15.5 4.0 1.9 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 PHD PF00628.29 CBK21931.2 - 0.0053 16.6 3.7 0.012 15.5 3.7 1.6 1 0 0 1 1 1 1 PHD-finger RINGv PF12906.7 CBK21931.2 - 0.017 15.2 5.3 0.039 14.1 5.3 1.6 1 0 0 1 1 1 0 RING-variant domain K1 PF02960.14 CBK21931.2 - 0.032 14.3 0.4 0.063 13.4 0.4 1.6 1 0 0 1 1 1 0 K1 glycoprotein zf-Nse PF11789.8 CBK21931.2 - 0.043 13.7 3.2 0.14 12.0 3.2 1.9 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Pribosyl_synth PF14572.6 CBK21931.2 - 0.05 13.6 0.1 0.076 13.0 0.1 1.3 1 0 0 1 1 1 0 Phosphoribosyl synthetase-associated domain COX14 PF14880.6 CBK21931.2 - 0.081 12.8 1.1 0.12 12.2 0.1 1.8 2 0 0 2 2 2 0 Cytochrome oxidase c assembly zf-RING_4 PF14570.6 CBK21931.2 - 0.086 12.6 4.1 0.23 11.3 4.1 1.7 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain FANCL_C PF11793.8 CBK21931.2 - 0.089 13.0 3.9 0.42 10.8 3.9 2.1 1 1 0 1 1 1 0 FANCL C-terminal domain zf-C3H2C3 PF17122.5 CBK21931.2 - 0.13 12.3 4.6 0.5 10.4 4.6 2.1 1 1 0 1 1 1 0 Zinc-finger zf-Di19 PF05605.12 CBK21931.2 - 0.15 12.4 1.5 10 6.5 0.0 2.5 2 1 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-C3HC4_4 PF15227.6 CBK21931.2 - 0.39 10.9 5.7 0.5 10.6 3.3 2.5 2 1 0 2 2 2 0 zinc finger of C3HC4-type, RING Prok-RING_1 PF14446.6 CBK21931.2 - 5.1 7.1 8.4 2 8.4 1.1 2.8 3 0 0 3 3 2 0 Prokaryotic RING finger family 1 Metallophos_2 PF12850.7 CBK21932.2 - 6e-09 36.3 0.0 8.3e-09 35.8 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain PhoLip_ATPase_C PF16212.5 CBK21933.2 - 3.6e-16 59.7 6.5 4.9e-16 59.2 6.5 1.1 1 0 0 1 1 1 1 Phospholipid-translocating P-type ATPase C-terminal Cation_ATPase PF13246.6 CBK21933.2 - 2.2e-07 30.9 0.0 1.6e-06 28.1 0.0 2.2 3 0 0 3 3 3 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 CBK21933.2 - 7.5e-07 29.6 0.0 0.0079 16.5 0.0 2.1 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 CBK21933.2 - 0.0071 16.1 0.0 0.015 15.1 0.0 1.4 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase PhoLip_ATPase_N PF16209.5 CBK21934.2 - 9.1e-13 47.7 5.3 4.3e-12 45.6 5.3 1.9 1 1 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal PUF PF00806.19 CBK21935.2 - 7.6e-40 132.4 5.0 3.8e-05 23.2 0.0 8.1 8 0 0 8 8 8 7 Pumilio-family RNA binding repeat Not1 PF04054.15 CBK21935.2 - 0.094 11.6 0.2 0.24 10.3 0.1 1.7 2 0 0 2 2 2 0 CCR4-Not complex component, Not1 C_Hendra PF16821.5 CBK21935.2 - 0.14 12.0 2.4 0.25 11.2 2.4 1.4 1 0 0 1 1 1 0 C protein from hendra and measles viruses LuxT_C PF18285.1 CBK21935.2 - 0.18 12.4 0.3 9.8 6.8 0.0 3.1 3 0 0 3 3 3 0 Tetracycline repressor LuxT C-terminal domain Utp12 PF04003.12 CBK21935.2 - 0.29 11.5 2.1 0.87 9.9 0.2 2.5 2 1 1 3 3 3 0 Dip2/Utp12 Family Presenilin PF01080.17 CBK21935.2 - 1 8.0 4.8 1.7 7.4 4.8 1.2 1 0 0 1 1 1 0 Presenilin MIF PF01187.18 CBK21936.2 - 0.01 16.1 0.0 0.011 16.0 0.0 1.0 1 0 0 1 1 1 0 Macrophage migration inhibitory factor (MIF) Sdh_cyt PF01127.22 CBK21938.2 - 5.2e-11 42.6 4.4 8.1e-11 42.0 4.4 1.2 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit Glyco_hydro_32N PF00251.20 CBK21938.2 - 0.12 11.9 0.2 0.17 11.5 0.2 1.2 1 0 0 1 1 1 0 Glycosyl hydrolases family 32 N-terminal domain Ribosomal_S10 PF00338.22 CBK21939.2 - 4.9e-27 94.0 1.0 6.2e-27 93.7 1.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e PriA_C PF18074.1 CBK21939.2 - 0.032 15.0 0.1 0.06 14.2 0.1 1.4 1 0 0 1 1 1 0 Primosomal protein N C-terminal domain Ribosomal_S19e PF01090.19 CBK21940.2 - 8e-35 119.5 0.0 8.6e-35 119.4 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S19e DUF2398 PF09661.10 CBK21940.2 - 0.038 13.2 0.0 0.04 13.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2398) HrcA_DNA-bdg PF03444.15 CBK21940.2 - 0.064 12.9 0.0 0.1 12.2 0.0 1.3 1 0 0 1 1 1 0 Winged helix-turn-helix transcription repressor, HrcA DNA-binding Ribosomal_L40e PF01020.17 CBK21941.2 - 4.1e-29 100.2 13.8 4.1e-29 100.2 13.8 1.7 2 0 0 2 2 2 1 Ribosomal L40e family ubiquitin PF00240.23 CBK21941.2 - 7.5e-18 64.1 0.0 1e-17 63.7 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 CBK21941.2 - 6.7e-10 38.7 0.1 1e-09 38.1 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like FGGY_C PF02782.16 CBK21942.2 - 5.5e-58 196.0 2.2 7.9e-58 195.4 2.2 1.2 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.21 CBK21942.2 - 2.1e-57 194.5 0.0 3.1e-57 193.9 0.0 1.3 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain RabGAP-TBC PF00566.18 CBK21943.2 - 6.9e-13 48.8 0.1 1.4e-11 44.5 0.1 2.2 1 1 0 1 1 1 1 Rab-GTPase-TBC domain RabGAP-TBC PF00566.18 CBK21944.2 - 1.7e-19 70.4 1.7 1.7e-19 70.4 1.7 2.0 2 1 0 2 2 2 1 Rab-GTPase-TBC domain DUF5582 PF17819.1 CBK21944.2 - 2.2 8.7 8.7 1.9 8.9 2.9 2.2 1 1 1 2 2 2 0 Family of unknown function (DUF5582) DUF1664 PF07889.12 CBK21944.2 - 5.6 7.0 9.4 0.86 9.7 1.1 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) FKBP_C PF00254.28 CBK21945.2 - 1.5e-13 50.9 0.0 1.9e-13 50.6 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase TFIIS_C PF01096.18 CBK21946.2 - 7.5e-15 54.5 1.0 7.5e-15 54.5 1.0 2.4 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) Baculo_LEF5_C PF11792.8 CBK21946.2 - 0.047 13.4 1.8 0.19 11.4 0.0 2.5 2 0 0 2 2 2 0 Baculoviridae late expression factor 5 C-terminal domain RecR PF02132.15 CBK21946.2 - 0.066 12.8 1.0 0.066 12.8 1.0 2.6 3 0 0 3 3 3 0 RecR protein DZR PF12773.7 CBK21946.2 - 0.18 11.9 8.5 0.32 11.0 0.5 2.7 2 1 0 2 2 2 0 Double zinc ribbon C1_1 PF00130.22 CBK21946.2 - 0.23 11.4 8.0 0.1 12.5 1.2 2.5 2 1 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Rpr2 PF04032.16 CBK21946.2 - 1.2 9.5 7.5 73 3.8 7.5 2.4 1 1 0 1 1 1 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain Auto_anti-p27 PF06677.12 CBK21946.2 - 1.5 9.1 10.2 5.1 7.4 2.5 2.6 2 1 0 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) Coatomer_WDAD PF04053.14 CBK21947.2 - 6.8e-84 282.5 0.0 2e-83 280.9 0.0 1.7 2 0 0 2 2 2 1 Coatomer WD associated region COPI_C PF06957.11 CBK21947.2 - 4.9e-73 246.2 0.4 7.1e-73 245.7 0.4 1.2 1 0 0 1 1 1 1 Coatomer (COPI) alpha subunit C-terminus WD40 PF00400.32 CBK21947.2 - 1.7e-45 152.1 17.9 7.1e-08 33.0 0.2 7.9 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBK21947.2 - 2.9e-11 43.5 5.5 0.002 18.4 0.1 5.0 3 2 0 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 CBK21947.2 - 0.004 15.9 9.3 0.49 9.0 0.3 3.9 2 1 2 4 4 4 2 Nucleoporin Nup120/160 FSH1 PF03959.13 CBK21948.2 - 3.2e-51 174.0 0.0 3.5e-51 173.9 0.0 1.0 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_2 PF02230.16 CBK21948.2 - 4.1e-07 30.0 0.0 7.1e-07 29.3 0.0 1.4 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.21 CBK21948.2 - 0.0065 16.0 0.0 0.026 14.0 0.0 1.9 1 1 1 2 2 2 1 Prolyl oligopeptidase family BAAT_C PF08840.11 CBK21948.2 - 0.016 15.1 0.5 0.07 13.0 0.0 2.0 1 1 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal DEAD PF00270.29 CBK21949.2 - 4.6e-46 156.8 0.3 8.8e-46 155.9 0.3 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CBK21949.2 - 3.7e-26 91.6 0.0 1.9e-25 89.4 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 CBK21949.2 - 1.4e-09 38.1 0.0 3.5e-09 36.9 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF4217 PF13959.6 CBK21949.2 - 1e-08 35.2 0.0 2.2e-08 34.2 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) AAA_22 PF13401.6 CBK21949.2 - 0.027 14.7 3.2 0.16 12.2 3.2 2.2 1 1 0 1 1 1 0 AAA domain ERCC3_RAD25_C PF16203.5 CBK21949.2 - 0.074 12.3 0.0 0.17 11.1 0.0 1.5 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase Urocanase PF01175.18 CBK21950.2 - 4.9e-87 291.0 0.0 8e-87 290.3 0.0 1.4 1 0 0 1 1 1 1 Urocanase Rossmann-like domain Urocanase_C PF17392.2 CBK21950.2 - 6e-87 290.2 0.4 9.3e-87 289.5 0.4 1.3 1 0 0 1 1 1 1 Urocanase C-terminal domain Urocanase_N PF17391.2 CBK21950.2 - 1.9e-56 189.2 0.7 7.5e-56 187.3 0.5 2.0 2 0 0 2 2 2 1 Urocanase N-terminal domain XRN_M PF17846.1 CBK21951.2 - 0.2 10.6 4.9 0.25 10.2 4.9 1.3 1 0 0 1 1 1 0 Xrn1 helical domain EST1_DNA_bind PF10373.9 CBK21953.2 - 4.1e-26 92.1 1.6 6e-26 91.6 1.6 1.2 1 0 0 1 1 1 1 Est1 DNA/RNA binding domain EST1 PF10374.9 CBK21953.2 - 1.4e-06 29.0 3.6 2.7e-06 28.1 1.1 2.6 3 1 0 3 3 3 1 Telomerase activating protein Est1 TPR_17 PF13431.6 CBK21953.2 - 0.068 13.6 0.4 0.22 12.0 0.0 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_11 PF13414.6 CBK21953.2 - 0.081 12.6 0.0 0.17 11.6 0.0 1.5 1 0 0 1 1 1 0 TPR repeat DUF4462 PF14692.6 CBK21954.2 - 3.3 7.3 9.6 9.4 5.8 1.5 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4462) Ndc1_Nup PF09531.10 CBK21954.2 - 4.7 5.8 6.0 7.4 5.1 6.0 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Trypsin_2 PF13365.6 CBK21956.2 - 0.0082 17.0 0.1 0.019 15.9 0.1 1.8 1 1 0 1 1 1 1 Trypsin-like peptidase domain SesA PF17107.5 CBK21957.2 - 0.1 12.8 0.0 0.14 12.3 0.0 1.2 1 0 0 1 1 1 0 N-terminal domain on NACHT_NTPase and P-loop NTPases Ribosomal_S8e PF01201.22 CBK21958.2 - 3.1e-46 157.0 4.7 1.5e-45 154.8 4.7 1.9 1 1 0 1 1 1 1 Ribosomal protein S8e UCH PF00443.29 CBK21959.2 - 1.2e-24 87.2 0.1 1.6e-24 86.8 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 CBK21959.2 - 4.3e-17 62.2 11.1 4.3e-17 62.2 11.1 2.7 4 0 0 4 4 4 1 Zn-finger in ubiquitin-hydrolases and other protein UCH_1 PF13423.6 CBK21959.2 - 3.6e-11 43.2 3.4 8.8e-05 22.2 0.1 2.2 1 1 1 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase Peptidase_C98 PF15499.6 CBK21959.2 - 4.1e-05 23.2 2.8 0.0036 16.8 0.4 2.4 2 0 0 2 2 2 2 Ubiquitin-specific peptidase-like, SUMO isopeptidase zf-UBP_var PF17807.1 CBK21960.2 - 7e-22 77.0 1.1 1.2e-21 76.2 1.1 1.4 1 0 0 1 1 1 1 Variant UBP zinc finger UBA_4 PF14555.6 CBK21960.2 - 1.3e-07 31.3 0.0 2.5e-07 30.4 0.0 1.5 1 0 0 1 1 1 1 UBA-like domain zf-UBP PF02148.19 CBK21960.2 - 0.0021 18.3 2.4 0.0021 18.3 2.4 2.2 2 1 0 2 2 2 1 Zn-finger in ubiquitin-hydrolases and other protein DUF2180 PF09947.9 CBK21960.2 - 0.012 15.5 1.0 0.042 13.8 0.2 2.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2180) zf-RING_10 PF16685.5 CBK21960.2 - 4 7.6 8.2 0.16 12.1 1.2 2.3 3 0 0 3 3 3 0 zinc RING finger of MSL2 Pkinase PF00069.25 CBK21961.2 - 3.5e-25 88.9 0.0 4.1e-25 88.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBK21961.2 - 4.6e-12 45.8 0.0 5.7e-12 45.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CBK21961.2 - 9.7e-05 21.3 0.0 0.00013 20.9 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 CBK21961.2 - 0.019 14.9 0.0 0.17 11.8 0.0 2.3 2 1 1 3 3 3 0 Phosphotransferase enzyme family TBPIP PF07106.13 CBK21962.2 - 1.6e-22 79.2 1.0 3e-22 78.3 1.0 1.4 1 0 0 1 1 1 1 TBPIP/Hop2 winged helix domain DUF5082 PF16888.5 CBK21962.2 - 0.00025 21.3 4.7 0.024 14.9 0.4 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF5082) Penicillinase_R PF03965.16 CBK21962.2 - 0.0012 19.2 2.1 0.074 13.4 0.3 3.0 1 1 2 3 3 3 1 Penicillinase repressor DivIC PF04977.15 CBK21962.2 - 0.0014 18.4 7.4 0.11 12.3 1.9 3.0 1 1 1 2 2 2 2 Septum formation initiator KASH_CCD PF14662.6 CBK21962.2 - 0.0025 17.7 7.4 0.0025 17.7 7.4 1.9 2 0 0 2 2 2 1 Coiled-coil region of CCDC155 or KASH Spc7 PF08317.11 CBK21962.2 - 0.0027 16.7 11.2 0.14 11.0 0.8 2.0 1 1 1 2 2 2 2 Spc7 kinetochore protein ATG16 PF08614.11 CBK21962.2 - 0.0047 17.2 9.5 0.074 13.3 9.5 2.1 1 1 0 1 1 1 1 Autophagy protein 16 (ATG16) DUF1192 PF06698.11 CBK21962.2 - 0.005 16.9 12.0 0.019 15.0 1.4 3.4 2 1 1 3 3 3 1 Protein of unknown function (DUF1192) Snapin_Pallidin PF14712.6 CBK21962.2 - 0.018 15.4 2.8 0.047 14.1 2.8 1.7 1 0 0 1 1 1 0 Snapin/Pallidin ADIP PF11559.8 CBK21962.2 - 0.023 14.8 8.3 7 6.7 8.3 2.7 1 1 0 1 1 1 0 Afadin- and alpha -actinin-Binding LZ3wCH PF18517.1 CBK21962.2 - 0.026 14.6 0.2 0.13 12.3 0.0 2.5 2 0 0 2 2 1 0 Leucine zipper with capping helix domain APG6_N PF17675.1 CBK21962.2 - 0.028 15.0 14.9 0.1 13.1 13.6 2.3 1 1 1 2 2 2 0 Apg6 coiled-coil region DUF3811 PF11656.8 CBK21962.2 - 0.049 14.0 2.5 0.1 13.0 0.0 2.2 2 1 0 2 2 2 0 YjbD family (DUF3811) WXG100 PF06013.12 CBK21962.2 - 0.054 13.7 3.6 0.76 10.0 1.9 2.9 2 1 0 2 2 2 0 Proteins of 100 residues with WXG Baculo_PEP_C PF04513.12 CBK21962.2 - 0.072 13.1 0.4 0.23 11.5 0.4 1.7 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus SlyX PF04102.12 CBK21962.2 - 0.074 13.7 6.8 4 8.1 1.8 3.1 1 1 2 3 3 3 0 SlyX Golgin_A5 PF09787.9 CBK21962.2 - 0.08 12.4 9.8 0.1 12.0 9.8 1.3 1 0 0 1 1 1 0 Golgin subfamily A member 5 HALZ PF02183.18 CBK21962.2 - 0.1 12.8 2.5 0.53 10.5 1.5 2.6 2 0 0 2 2 2 0 Homeobox associated leucine zipper ZapB PF06005.12 CBK21962.2 - 0.12 12.8 9.4 39 4.8 9.4 2.6 1 1 0 1 1 1 0 Cell division protein ZapB BLOC1_2 PF10046.9 CBK21962.2 - 0.12 12.7 6.4 0.06 13.6 3.7 1.9 2 0 0 2 2 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Rx_N PF18052.1 CBK21962.2 - 0.13 12.5 3.1 0.34 11.2 3.1 1.7 1 0 0 1 1 1 0 Rx N-terminal domain DUF5320 PF17253.2 CBK21962.2 - 0.14 13.2 2.5 0.16 13.0 1.4 1.8 1 1 1 2 2 1 0 Family of unknown function (DUF5320) FlxA PF14282.6 CBK21962.2 - 0.16 11.9 5.5 0.47 10.5 5.5 1.9 1 1 0 1 1 1 0 FlxA-like protein DASH_Spc19 PF08287.11 CBK21962.2 - 0.2 11.5 5.8 0.38 10.6 5.7 1.5 1 1 0 1 1 1 0 Spc19 ABC_tran_CTD PF16326.5 CBK21962.2 - 0.21 11.9 18.0 6.7 7.0 6.5 3.1 1 1 1 2 2 2 0 ABC transporter C-terminal domain DUF1664 PF07889.12 CBK21962.2 - 0.21 11.6 3.6 0.44 10.6 2.7 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) bZIP_1 PF00170.21 CBK21962.2 - 0.24 11.5 9.5 0.62 10.2 4.8 3.1 1 1 0 2 2 2 0 bZIP transcription factor Cnn_1N PF07989.11 CBK21962.2 - 0.25 11.5 8.2 0.33 11.1 3.8 2.9 1 1 2 3 3 3 0 Centrosomin N-terminal motif 1 Ax_dynein_light PF10211.9 CBK21962.2 - 0.27 11.2 8.9 0.43 10.5 6.7 2.3 1 1 1 2 2 2 0 Axonemal dynein light chain FUSC PF04632.12 CBK21962.2 - 0.28 9.7 2.4 0.34 9.4 2.4 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family TMF_DNA_bd PF12329.8 CBK21962.2 - 0.28 11.2 11.7 3.1 7.9 11.5 2.6 1 1 0 1 1 1 0 TATA element modulatory factor 1 DNA binding Prominin PF05478.11 CBK21962.2 - 0.33 8.9 4.2 0.41 8.5 3.8 1.3 1 1 0 1 1 1 0 Prominin GAS PF13851.6 CBK21962.2 - 0.33 10.3 10.7 1.1 8.6 10.8 2.0 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding Cep57_CLD_2 PF14197.6 CBK21962.2 - 0.37 10.9 6.1 0.2 11.8 2.2 2.3 1 1 1 2 2 2 0 Centrosome localisation domain of PPC89 TMPIT PF07851.13 CBK21962.2 - 0.41 9.8 4.8 0.68 9.1 4.3 1.6 1 1 1 2 2 2 0 TMPIT-like protein DUF465 PF04325.13 CBK21962.2 - 0.42 10.7 4.9 2.7 8.1 1.9 3.0 1 1 1 2 2 2 0 Protein of unknown function (DUF465) E2F_CC-MB PF16421.5 CBK21962.2 - 0.43 11.0 3.9 6.9 7.1 1.8 2.5 1 1 1 2 2 2 0 E2F transcription factor CC-MB domain DUF1910 PF08928.10 CBK21962.2 - 0.46 10.5 4.1 14 5.7 0.0 2.7 2 1 1 3 3 2 0 Domain of unknown function (DUF1910) Mnd1 PF03962.15 CBK21962.2 - 0.57 10.5 4.5 1.1 9.6 0.1 2.8 2 1 1 3 3 3 0 Mnd1 HTH domain Prefoldin_2 PF01920.20 CBK21962.2 - 0.62 10.1 9.8 6 6.9 4.5 3.0 1 1 1 2 2 2 0 Prefoldin subunit TPR_MLP1_2 PF07926.12 CBK21962.2 - 0.65 10.1 11.7 4.1 7.5 11.7 2.3 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein YabA PF06156.13 CBK21962.2 - 0.83 10.3 9.3 4.4 8.0 1.8 2.7 2 1 1 3 3 2 0 Initiation control protein YabA DUF724 PF05266.14 CBK21962.2 - 0.85 9.4 10.0 0.41 10.5 1.9 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF724) FapA PF03961.13 CBK21962.2 - 0.93 8.0 10.1 0.44 9.1 5.7 2.0 1 1 1 2 2 2 0 Flagellar Assembly Protein A Fez1 PF06818.15 CBK21962.2 - 1.1 9.7 10.6 1.5 9.2 10.6 1.5 1 1 0 1 1 1 0 Fez1 PRKG1_interact PF15898.5 CBK21962.2 - 1.5 9.7 11.7 0.66 10.9 2.2 3.2 1 1 1 2 2 2 0 cGMP-dependent protein kinase interacting domain Fib_alpha PF08702.10 CBK21962.2 - 1.9 8.7 6.3 6.5 6.9 4.5 2.2 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Seryl_tRNA_N PF02403.22 CBK21962.2 - 2 8.7 9.8 1.6 9.0 6.8 2.2 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Swi5 PF07061.11 CBK21962.2 - 2.1 8.5 7.0 26 5.0 7.0 2.9 1 1 0 1 1 1 0 Swi5 DUF1319 PF07028.11 CBK21962.2 - 2.2 8.6 6.5 2.1 8.6 2.4 2.7 1 1 2 3 3 3 0 Protein of unknown function (DUF1319) FAM76 PF16046.5 CBK21962.2 - 2.3 7.5 6.3 12 5.1 6.3 1.9 1 1 0 1 1 1 0 FAM76 protein V-SNARE PF05008.15 CBK21962.2 - 3.1 8.2 11.0 8.7 6.8 2.1 3.1 1 1 2 3 3 3 0 Vesicle transport v-SNARE protein N-terminus THOC7 PF05615.13 CBK21962.2 - 3.9 7.8 11.1 2.4e+02 2.0 8.9 3.1 2 1 0 2 2 2 0 Tho complex subunit 7 FlaC_arch PF05377.11 CBK21962.2 - 5 7.6 13.7 0.74 10.3 3.0 3.5 2 1 2 4 4 3 0 Flagella accessory protein C (FlaC) CCDC-167 PF15188.6 CBK21962.2 - 5.3 7.5 10.0 12 6.4 5.2 3.0 1 1 2 3 3 3 0 Coiled-coil domain-containing protein 167 Ribosomal_L29 PF00831.23 CBK21962.2 - 6.3 6.9 8.9 0.61 10.1 0.9 2.7 1 1 1 2 2 2 0 Ribosomal L29 protein Spc24 PF08286.11 CBK21962.2 - 7 7.0 13.7 16 5.8 10.2 2.8 2 1 0 2 2 1 0 Spc24 subunit of Ndc80 zf-CCCH PF00642.24 CBK21963.2 - 3.6e-06 26.7 24.3 1.4e-05 24.9 5.1 3.0 2 1 1 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 CBK21963.2 - 0.00043 21.0 18.3 0.00054 20.6 3.1 3.0 2 1 2 4 4 4 2 Torus domain zf_CCCH_4 PF18345.1 CBK21963.2 - 0.0012 18.8 22.0 0.023 14.8 5.6 3.9 3 1 0 3 3 3 2 Zinc finger domain zf-CCCH_3 PF15663.5 CBK21963.2 - 0.0041 17.3 12.7 0.26 11.5 1.8 3.2 1 1 1 2 2 2 2 Zinc-finger containing family zf-CCCH_4 PF18044.1 CBK21963.2 - 0.0065 16.2 23.8 0.013 15.3 4.9 4.2 3 1 0 3 3 3 1 CCCH-type zinc finger zf-CCCH_2 PF14608.6 CBK21963.2 - 3.5 8.2 29.4 0.5 10.9 3.3 4.4 4 0 0 4 4 4 0 RNA-binding, Nab2-type zinc finger GD_AH_C PF04295.13 CBK21964.2 - 1.3e-114 383.1 0.0 3.8e-109 365.1 0.0 2.1 2 0 0 2 2 2 2 D-galactarate dehydratase / Altronate hydrolase, C terminus SAF PF08666.12 CBK21964.2 - 0.0056 17.3 0.0 0.013 16.1 0.0 1.7 1 0 0 1 1 1 1 SAF domain Glyco_transf_22 PF03901.17 CBK21965.2 - 1.3e-28 100.4 22.6 1.6e-28 100.1 22.6 1.0 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family DUF3043 PF11241.8 CBK21965.2 - 5.3 7.1 4.3 26 4.8 0.4 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3043) Longin PF13774.6 CBK21966.2 - 2e-16 59.8 0.4 3.7e-16 58.9 0.4 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain Synaptobrevin PF00957.21 CBK21966.2 - 6.7e-14 51.4 0.5 2.3e-13 49.8 0.1 1.9 2 0 0 2 2 2 1 Synaptobrevin Sedlin_N PF04628.13 CBK21967.2 - 0.023 14.8 0.2 0.034 14.3 0.2 1.4 1 1 0 1 1 1 0 Sedlin, N-terminal conserved region G10 PF01125.17 CBK21968.2 - 1.3e-50 170.9 9.0 1.5e-50 170.8 9.0 1.0 1 0 0 1 1 1 1 G10 protein DUF2387 PF09526.10 CBK21968.2 - 2.8 8.2 10.2 0.57 10.4 0.5 2.5 1 1 1 2 2 2 0 Probable metal-binding protein (DUF2387) SPASM PF13186.6 CBK21970.2 - 0.1 13.1 0.2 0.25 11.9 0.1 1.7 2 0 0 2 2 2 0 Iron-sulfur cluster-binding domain Peptidase_U57 PF05582.12 CBK21971.2 - 0.085 12.1 2.6 3.2 6.9 0.0 2.0 1 1 1 2 2 2 0 YabG peptidase U57 rRNA_proc-arch PF13234.6 CBK21972.2 - 2e-63 214.8 1.3 2.2e-63 214.7 0.0 1.7 2 0 0 2 2 2 1 rRNA-processing arch domain DSHCT PF08148.12 CBK21972.2 - 2.5e-47 160.6 1.0 2.1e-46 157.6 0.6 2.5 3 0 0 3 3 3 1 DSHCT (NUC185) domain DEAD PF00270.29 CBK21972.2 - 1e-09 38.4 0.0 5.3e-09 36.1 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CBK21972.2 - 8.1e-08 32.6 0.0 5.3e-07 30.0 0.0 2.5 1 1 0 1 1 1 1 Helicase conserved C-terminal domain DUF3450 PF11932.8 CBK21972.2 - 0.0017 17.7 0.1 0.0042 16.4 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3450) bZIP_1 PF00170.21 CBK21972.2 - 0.042 14.0 0.3 0.042 14.0 0.3 2.0 2 0 0 2 2 2 0 bZIP transcription factor DivIC PF04977.15 CBK21972.2 - 0.071 12.9 3.5 0.078 12.8 0.4 2.5 2 0 0 2 2 2 0 Septum formation initiator APG6_N PF17675.1 CBK21972.2 - 0.13 12.8 0.2 0.13 12.8 0.2 3.5 4 0 0 4 4 4 0 Apg6 coiled-coil region Pkinase PF00069.25 CBK21973.2 - 1.3e-66 224.7 0.0 1.4e-66 224.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBK21973.2 - 1.5e-35 122.7 0.0 2e-35 122.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CBK21973.2 - 4.6e-06 25.7 0.0 7.9e-06 24.9 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 CBK21973.2 - 0.0034 16.7 0.0 0.0045 16.3 0.0 1.2 1 0 0 1 1 1 1 Kinase-like DUF3991 PF13154.6 CBK21973.2 - 0.19 12.1 0.3 0.64 10.4 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3991) UDPGP PF01704.18 CBK21974.2 - 3.4e-14 52.3 0.0 4.3e-14 52.0 0.0 1.1 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase NTP_transf_3 PF12804.7 CBK21974.2 - 0.1 13.0 0.1 0.2 12.0 0.1 1.6 1 1 0 1 1 1 0 MobA-like NTP transferase domain UDPGP PF01704.18 CBK21975.2 - 4e-25 88.3 0.0 5.7e-25 87.8 0.0 1.2 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase DnaJ_C PF01556.18 CBK21976.2 - 8.7e-37 126.5 0.0 1.4e-36 125.8 0.0 1.4 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 CBK21976.2 - 1.9e-21 75.9 1.5 3.9e-21 74.9 1.5 1.6 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 CBK21976.2 - 1.8e-14 53.9 14.5 3.4e-14 52.9 14.5 1.5 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 CBK21976.2 - 0.0028 17.6 2.7 0.0028 17.6 2.7 2.7 1 1 1 2 2 2 1 Tryptophan RNA-binding attenuator protein inhibitory protein DZR PF12773.7 CBK21976.2 - 0.072 13.1 6.5 1.9 8.6 0.6 2.4 2 0 0 2 2 2 0 Double zinc ribbon Suf PF05843.14 CBK21976.2 - 0.076 13.0 8.6 0.16 12.0 8.6 1.5 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) DDHD PF02862.17 CBK21976.2 - 0.095 12.9 2.7 0.2 11.8 2.7 1.6 1 0 0 1 1 1 0 DDHD domain DUF3482 PF11981.8 CBK21976.2 - 0.15 11.4 0.8 0.25 10.7 0.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3482) CCDC106 PF15794.5 CBK21976.2 - 0.15 11.8 13.6 0.3 10.8 13.6 1.4 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 HypA PF01155.19 CBK21976.2 - 0.22 11.5 10.4 1.7 8.7 1.5 2.5 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zinc-ribbons_6 PF07191.12 CBK21976.2 - 1.2 9.2 5.9 5.9 7.0 1.2 2.5 2 0 0 2 2 2 0 zinc-ribbons SAPS PF04499.15 CBK21976.2 - 1.7 7.3 18.1 2.5 6.8 18.1 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Vfa1 PF08432.10 CBK21976.2 - 2.2 8.6 30.2 4.6 7.5 30.2 1.5 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Mitofilin PF09731.9 CBK21976.2 - 3.1 6.5 28.4 4.8 5.9 28.4 1.2 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Endostatin PF06482.11 CBK21976.2 - 3.4 7.1 8.6 5.3 6.4 8.6 1.2 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin Spore_coat_CotO PF14153.6 CBK21976.2 - 4.2 7.3 27.9 7.8 6.4 27.9 1.4 1 0 0 1 1 1 0 Spore coat protein CotO HSP70 PF00012.20 CBK21976.2 - 4.4 5.4 17.1 6 4.9 17.1 1.2 1 0 0 1 1 1 0 Hsp70 protein Pkinase PF00069.25 CBK21977.2 - 0.00012 21.6 0.0 0.00013 21.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain tRNA-synt_2c PF01411.19 CBK21978.2 - 2.2e-131 439.1 0.0 2.8e-131 438.7 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (A) tRNA_SAD PF07973.14 CBK21978.2 - 1.3e-07 31.6 0.3 2.7e-07 30.6 0.3 1.5 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain Spike_rec_bind PF09408.10 CBK21979.2 - 0.0017 18.1 0.4 0.0028 17.4 0.4 1.3 1 0 0 1 1 1 1 Spike receptor binding domain Sialidase PF02973.16 CBK21979.2 - 0.014 14.9 0.1 0.042 13.4 0.0 1.7 1 1 0 1 1 1 0 Sialidase, N-terminal domain LRR_8 PF13855.6 CBK21979.2 - 0.2 11.4 1.1 1.7 8.5 0.0 2.9 4 0 0 4 4 4 0 Leucine rich repeat Sec5 PF15469.6 CBK21981.2 - 0.0056 16.5 1.8 0.0059 16.4 0.2 1.8 2 0 0 2 2 2 1 Exocyst complex component Sec5 DUF2760 PF10816.8 CBK21981.2 - 0.14 12.0 0.1 2.5 8.0 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF2760) Carbpep_Y_N PF05388.11 CBK21981.2 - 0.24 11.9 3.3 19 5.8 0.1 3.1 3 0 0 3 3 3 0 Carboxypeptidase Y pro-peptide Sec5 PF15469.6 CBK21982.2 - 0.0011 18.8 0.0 0.0018 18.1 0.0 1.3 1 0 0 1 1 1 1 Exocyst complex component Sec5 Vps51 PF08700.11 CBK21982.2 - 0.0039 17.2 0.0 0.006 16.6 0.0 1.4 1 0 0 1 1 1 1 Vps51/Vps67 tRNA-synt_2c PF01411.19 CBK21983.2 - 3.6e-210 699.2 0.1 1.1e-209 697.6 0.0 1.7 2 0 0 2 2 2 1 tRNA synthetases class II (A) DHHA1 PF02272.19 CBK21983.2 - 9.3e-13 48.8 6.2 2e-12 47.7 4.3 2.3 1 1 1 2 2 2 1 DHHA1 domain tRNA_SAD PF07973.14 CBK21983.2 - 2.2e-12 46.9 0.0 5.2e-12 45.7 0.0 1.6 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain AcylCoA_dehyd_C PF12186.8 CBK21983.2 - 0.13 12.4 2.0 0.32 11.1 2.0 1.7 1 0 0 1 1 1 0 Acyl-CoA dehydrogenase C terminal DUF99 PF01949.16 CBK21983.2 - 0.19 11.1 0.9 0.63 9.4 1.1 1.7 2 0 0 2 2 2 0 Protein of unknown function DUF99 RPN2_C PF18004.1 CBK21983.2 - 0.34 10.8 6.4 0.81 9.6 6.4 1.5 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain HSP20 PF00011.21 CBK21984.2 - 5.7e-27 93.9 2.3 6.8e-27 93.6 2.3 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 CBK21984.2 - 3e-13 49.1 0.0 5e-13 48.4 0.0 1.4 1 0 0 1 1 1 1 HSP20-like domain found in ArsA YqzE PF14038.6 CBK21984.2 - 0.72 9.9 2.6 0.99 9.5 0.3 2.4 3 0 0 3 3 3 0 YqzE-like protein Cpn60_TCP1 PF00118.24 CBK21985.2 - 2.1e-164 547.8 2.0 2.4e-164 547.6 2.0 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Cullin PF00888.22 CBK21986.2 - 1.9e-46 158.9 6.8 1.9e-46 158.9 6.8 1.6 2 0 0 2 2 2 1 Cullin family Cullin_Nedd8 PF10557.9 CBK21986.2 - 1.6e-06 28.1 0.2 6.6e-06 26.1 0.2 2.1 1 0 0 1 1 1 1 Cullin protein neddylation domain Phage_int_SAM_4 PF13495.6 CBK21986.2 - 0.001 19.5 0.2 2 9.0 0.0 3.9 3 0 0 3 3 3 1 Phage integrase, N-terminal SAM-like domain HTH_24 PF13412.6 CBK21986.2 - 0.0068 16.0 0.0 0.034 13.7 0.0 2.4 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding SirA PF10747.9 CBK21986.2 - 0.12 12.7 5.3 0.095 13.0 0.8 2.7 2 0 0 2 2 2 0 Sporulation inhibitor of replication protein SirA HTH_11 PF08279.12 CBK21986.2 - 1.6 8.7 5.1 0.91 9.5 0.0 3.1 4 0 0 4 4 4 0 HTH domain Porin_3 PF01459.22 CBK21987.2 - 3.4e-17 62.8 0.2 3.9e-17 62.6 0.2 1.0 1 0 0 1 1 1 1 Eukaryotic porin DER1 PF04511.15 CBK21988.2 - 2.3e-29 102.7 7.8 2.6e-29 102.5 7.8 1.0 1 0 0 1 1 1 1 Der1-like family UCH PF00443.29 CBK21989.2 - 2.3e-48 165.0 0.0 3.5e-25 89.0 11.5 2.4 1 1 1 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase Ctr PF04145.15 CBK21989.2 - 1.7 9.3 0.0 1.7 9.3 0.0 3.4 1 1 1 2 2 2 0 Ctr copper transporter family DUF543 PF04418.12 CBK21990.2 - 3.9e-07 30.0 0.1 4.8e-07 29.7 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF543) MtrF PF09472.10 CBK21990.2 - 0.095 12.1 0.2 0.2 11.1 0.2 1.5 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, F subunit (MtrF) PHD PF00628.29 CBK21991.2 - 1.6e-05 24.7 17.5 1.6e-05 24.7 17.5 2.6 2 1 0 2 2 2 1 PHD-finger PHD_2 PF13831.6 CBK21991.2 - 1.8e-05 24.2 9.9 1.8e-05 24.2 9.9 2.1 2 0 0 2 2 2 1 PHD-finger NAD_binding_6 PF08030.12 CBK21992.2 - 6.2e-13 49.2 0.0 1e-12 48.5 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.19 CBK21992.2 - 0.0031 17.6 1.9 0.0054 16.8 1.9 1.4 1 0 0 1 1 1 1 Ferric reductase like transmembrane component UCH PF00443.29 CBK21993.2 - 9.6e-06 25.3 0.0 1.1e-05 25.0 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 CBK21993.2 - 5.7e-05 22.9 0.1 6.1e-05 22.8 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-FPG_IleRS PF06827.14 CBK21993.2 - 0.015 15.2 0.1 0.032 14.1 0.1 1.6 1 0 0 1 1 1 0 Zinc finger found in FPG and IleRS UCH PF00443.29 CBK21994.2 - 4.8e-33 114.7 0.0 5.3e-33 114.6 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 CBK21994.2 - 3.3e-08 33.5 0.3 0.00026 20.7 0.0 2.1 1 1 1 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase DUF3506 PF12014.8 CBK21995.2 - 0.026 14.5 0.4 0.033 14.2 0.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3506) ANAPC4_WD40 PF12894.7 CBK21996.2 - 3.2e-13 49.8 0.3 7.8e-05 22.9 0.0 3.5 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 CBK21996.2 - 3.5e-10 40.3 14.7 0.15 13.0 0.1 5.9 6 0 0 6 6 6 5 WD domain, G-beta repeat FlgD_ig PF13860.6 CBK21996.2 - 0.042 13.7 0.2 0.9 9.4 0.0 2.4 2 0 0 2 2 2 0 FlgD Ig-like domain PQQ_2 PF13360.6 CBK21996.2 - 0.065 12.8 0.1 1.2 8.7 0.0 2.3 2 1 0 2 2 2 0 PQQ-like domain Nop PF01798.18 CBK21997.2 - 4.1e-66 222.7 0.0 5.7e-66 222.3 0.0 1.2 1 0 0 1 1 1 1 snoRNA binding domain, fibrillarin Prp31_C PF09785.9 CBK21997.2 - 1.7e-25 90.3 2.1 4e-25 89.1 2.1 1.5 1 0 0 1 1 1 1 Prp31 C terminal domain Stealth_CR2 PF11380.8 CBK21998.2 - 5.2e-46 155.3 1.4 8.1e-45 151.5 0.2 2.1 2 0 0 2 2 2 1 Stealth protein CR2, conserved region 2 Stealth_CR1 PF17101.5 CBK21998.2 - 1.1e-14 53.8 1.9 1.9e-14 53.1 1.9 1.4 1 0 0 1 1 1 1 Stealth protein CR1, conserved region 1 AAA_18 PF13238.6 CBK21999.2 - 2.6e-16 60.3 0.2 5.9e-16 59.2 0.0 1.6 2 0 0 2 2 2 1 AAA domain Porin_3 PF01459.22 CBK22000.2 - 6e-16 58.7 0.2 7.1e-16 58.5 0.2 1.1 1 0 0 1 1 1 1 Eukaryotic porin Rep_fac-A_3 PF08661.11 CBK22001.2 - 5.9e-16 58.7 0.0 7.4e-16 58.4 0.0 1.1 1 0 0 1 1 1 1 Replication factor A protein 3 RNase_T PF00929.24 CBK22002.2 - 5.8e-15 56.2 0.0 8.2e-15 55.7 0.0 1.2 1 0 0 1 1 1 1 Exonuclease Cpn60_TCP1 PF00118.24 CBK22003.2 - 2.1e-164 547.8 2.0 2.4e-164 547.6 2.0 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family HSP20 PF00011.21 CBK22004.2 - 5.7e-27 93.9 2.3 6.8e-27 93.6 2.3 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 CBK22004.2 - 3e-13 49.1 0.0 5e-13 48.4 0.0 1.4 1 0 0 1 1 1 1 HSP20-like domain found in ArsA YqzE PF14038.6 CBK22004.2 - 0.72 9.9 2.6 0.99 9.5 0.3 2.4 3 0 0 3 3 3 0 YqzE-like protein DUF5627 PF18620.1 CBK22005.2 - 0.032 14.1 0.3 17 5.3 0.0 3.5 3 0 0 3 3 3 0 Family of unknown function (DUF5627) Pkinase PF00069.25 CBK22006.2 - 5.2e-44 150.6 0.0 7.1e-44 150.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBK22006.2 - 1.6e-23 83.3 0.0 2e-23 83.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CBK22006.2 - 6.4e-06 25.7 0.1 0.0028 17.0 0.0 2.3 2 0 0 2 2 2 2 Kinase-like APH PF01636.23 CBK22006.2 - 1.4e-05 25.2 0.2 0.004 17.1 0.0 2.6 2 1 1 3 3 3 2 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 CBK22006.2 - 0.0064 15.6 0.0 0.0094 15.0 0.0 1.2 1 0 0 1 1 1 1 Seadornavirus VP7 CDC45 PF02724.14 CBK22006.2 - 0.048 11.9 3.3 0.059 11.7 3.3 1.3 1 0 0 1 1 1 0 CDC45-like protein PPP4R2 PF09184.11 CBK22006.2 - 10 5.6 16.0 1.8 8.1 12.2 1.7 2 0 0 2 2 2 0 PPP4R2 V-SNARE_C PF12352.8 CBK22007.2 - 1.6e-05 25.1 3.2 4.9e-05 23.5 2.9 1.8 1 1 1 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.13 CBK22007.2 - 2.9e-05 23.9 0.8 4e-05 23.4 0.8 1.3 1 0 0 1 1 1 1 Sec20 Orf78 PF06024.12 CBK22007.2 - 0.014 15.6 0.1 0.021 15.1 0.1 1.3 1 0 0 1 1 1 0 Orf78 (ac78) Chordopox_A13L PF05961.11 CBK22007.2 - 0.025 14.8 0.3 0.045 14.0 0.3 1.5 1 0 0 1 1 1 0 Chordopoxvirus A13L protein GP41 PF00517.17 CBK22007.2 - 0.046 13.6 0.1 0.052 13.5 0.1 1.1 1 0 0 1 1 1 0 Retroviral envelope protein Amnionless PF14828.6 CBK22007.2 - 0.22 10.3 0.4 0.23 10.2 0.4 1.0 1 0 0 1 1 1 0 Amnionless Synaptobrevin PF00957.21 CBK22007.2 - 0.5 10.2 5.2 1.1 9.1 5.2 1.6 1 1 0 1 1 1 0 Synaptobrevin DUF948 PF06103.11 CBK22007.2 - 8.9 6.6 8.7 0.64 10.3 1.7 2.1 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) WD40 PF00400.32 CBK22008.2 - 2.6e-15 56.6 4.6 0.0028 18.4 0.0 5.3 4 1 1 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBK22008.2 - 2.6e-12 46.9 0.0 0.0015 18.8 0.0 4.4 2 2 1 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 CBK22008.2 - 2e-05 23.5 1.0 0.089 11.4 0.0 2.2 1 1 1 2 2 2 2 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.16 CBK22008.2 - 0.00028 19.6 0.0 0.025 13.1 0.0 2.2 1 1 0 2 2 2 2 Cytochrome D1 heme domain Ge1_WD40 PF16529.5 CBK22008.2 - 0.00098 18.2 0.5 0.32 9.9 0.0 2.7 3 0 0 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein SGL PF08450.12 CBK22008.2 - 0.0065 16.1 0.0 0.084 12.4 0.0 2.3 1 1 1 2 2 2 2 SMP-30/Gluconolactonase/LRE-like region DUF2694 PF10904.8 CBK22008.2 - 0.019 15.0 0.5 0.034 14.2 0.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2694) Cpn10 PF00166.21 CBK22010.2 - 7.6e-26 90.0 0.0 8.5e-26 89.9 0.0 1.0 1 0 0 1 1 1 1 Chaperonin 10 Kd subunit TPR_12 PF13424.6 CBK22011.2 - 1.1e-13 51.3 0.7 5.3e-05 23.4 0.3 4.6 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_7 PF13176.6 CBK22011.2 - 1.1e-09 37.6 0.8 0.015 15.3 0.0 5.9 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_2 PF07719.17 CBK22011.2 - 2.7e-08 33.3 6.8 0.15 12.3 0.0 6.4 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_8 PF13181.6 CBK22011.2 - 4.6e-08 32.7 5.7 0.21 11.9 0.0 5.8 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_14 PF13428.6 CBK22011.2 - 9.8e-08 32.2 0.6 0.25 12.3 0.0 6.0 5 1 1 6 6 6 1 Tetratricopeptide repeat TPR_6 PF13174.6 CBK22011.2 - 1.1e-06 28.8 1.4 3.5 8.5 0.0 6.4 7 0 0 7 7 5 1 Tetratricopeptide repeat TPR_10 PF13374.6 CBK22011.2 - 8.1e-05 22.4 0.2 0.0053 16.6 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 CBK22011.2 - 0.0001 22.8 0.4 0.064 13.8 0.3 3.9 4 1 0 4 4 3 1 Tetratricopeptide repeat LRR_4 PF12799.7 CBK22011.2 - 0.00025 21.4 1.0 0.00066 20.0 0.2 2.3 2 0 0 2 2 1 1 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 CBK22011.2 - 0.00034 20.4 1.6 0.028 14.5 0.2 3.5 3 0 0 3 3 3 1 Leucine Rich repeat TPR_1 PF00515.28 CBK22011.2 - 0.00044 20.0 8.2 0.023 14.5 0.0 5.5 6 1 1 7 7 7 1 Tetratricopeptide repeat TPR_16 PF13432.6 CBK22011.2 - 0.0028 18.3 1.6 0.03 14.9 0.1 3.4 4 1 0 4 4 3 1 Tetratricopeptide repeat TPR_17 PF13431.6 CBK22011.2 - 0.0071 16.6 0.0 20 5.9 0.0 4.9 5 1 0 5 5 5 0 Tetratricopeptide repeat TPR_9 PF13371.6 CBK22011.2 - 0.032 14.4 0.0 0.2 11.9 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_MalT PF17874.1 CBK22011.2 - 0.034 13.5 0.0 0.17 11.2 0.0 2.0 2 1 1 3 3 3 0 MalT-like TPR region MIT PF04212.18 CBK22011.2 - 0.1 12.7 3.1 1.2 9.3 0.1 3.5 4 0 0 4 4 4 0 MIT (microtubule interacting and transport) domain E1-E2_ATPase PF00122.20 CBK22014.2 - 4.5e-39 133.9 3.1 6.1e-39 133.4 0.1 2.4 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 CBK22014.2 - 4.1e-37 127.7 10.1 4.1e-37 127.7 10.1 2.1 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 CBK22014.2 - 5e-19 69.4 0.2 1.1e-14 55.2 0.1 3.0 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 CBK22014.2 - 2.4e-16 59.6 0.0 5.6e-16 58.4 0.0 1.7 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 CBK22014.2 - 0.0076 16.0 0.2 0.098 12.4 0.3 2.4 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase KRTAP PF11759.8 CBK22015.2 - 0.0062 17.1 11.2 0.012 16.1 11.2 1.5 1 0 0 1 1 1 1 Keratin-associated matrix Keratin_2_head PF16208.5 CBK22015.2 - 4.2 7.5 21.9 5.9 7.0 21.9 1.4 1 1 0 1 1 1 0 Keratin type II head tRNA_m1G_MT PF01746.21 CBK22016.2 - 9.1e-20 71.2 0.1 9.1e-20 71.2 0.1 1.6 2 0 0 2 2 2 1 tRNA (Guanine-1)-methyltransferase Ribosomal_L37 PF08561.10 CBK22017.2 - 3.5e-09 37.2 1.9 4.7e-09 36.8 1.6 1.5 1 1 0 1 1 1 1 Mitochondrial ribosomal protein L37 LRR_6 PF13516.6 CBK22018.2 - 1.8e-09 36.9 19.2 0.034 14.2 0.1 11.3 14 0 0 14 14 14 3 Leucine Rich repeat LRR_4 PF12799.7 CBK22018.2 - 9.8e-08 32.2 21.7 0.14 12.6 2.4 9.0 9 2 1 10 10 10 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CBK22018.2 - 0.0017 18.1 23.1 2.8 7.8 4.0 9.3 11 2 1 12 12 12 2 Leucine rich repeat LRR_1 PF00560.33 CBK22018.2 - 2.1 9.2 29.9 0.77 10.5 0.2 9.1 10 1 0 10 10 10 0 Leucine Rich Repeat HAD PF12710.7 CBK22019.2 - 8.7e-14 52.3 0.0 1.2e-13 51.9 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 CBK22019.2 - 8.2e-05 23.0 0.0 0.0021 18.3 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase UMPH-1 PF05822.12 CBK22019.2 - 0.0001 21.9 0.0 0.00014 21.5 0.0 1.1 1 0 0 1 1 1 1 Pyrimidine 5'-nucleotidase (UMPH-1) Rdx PF10262.9 CBK22020.2 - 4.2e-05 23.7 0.0 5.4e-05 23.3 0.0 1.4 1 1 0 1 1 1 1 Rdx family EphA2_TM PF14575.6 CBK22020.2 - 0.21 12.5 1.2 1.5 9.7 0.0 2.3 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Nsp1_C PF05064.13 CBK22021.2 - 4.7e-13 49.0 9.6 2.5e-10 40.2 5.3 2.3 1 1 1 2 2 2 2 Nsp1-like C-terminal region DUF1664 PF07889.12 CBK22021.2 - 3e-05 24.1 8.7 0.00087 19.3 3.8 2.9 3 0 0 3 3 3 1 Protein of unknown function (DUF1664) Snapin_Pallidin PF14712.6 CBK22021.2 - 0.0001 22.6 10.6 0.0049 17.3 4.6 3.1 2 1 1 3 3 3 1 Snapin/Pallidin NPV_P10 PF05531.12 CBK22021.2 - 0.00012 22.5 3.9 0.0026 18.2 0.1 3.0 1 1 1 2 2 2 1 Nucleopolyhedrovirus P10 protein Baculo_PEP_C PF04513.12 CBK22021.2 - 0.00022 21.3 1.9 0.099 12.7 0.0 2.3 1 1 1 2 2 2 1 Baculovirus polyhedron envelope protein, PEP, C terminus DUF16 PF01519.16 CBK22021.2 - 0.00037 20.9 9.5 0.026 15.0 0.5 2.2 1 1 0 2 2 2 2 Protein of unknown function DUF16 Vac_Fusion PF02346.16 CBK22021.2 - 0.00044 19.8 3.9 0.3 10.8 0.0 3.3 4 0 0 4 4 3 2 Chordopoxvirus multifunctional envelope protein A27 DUF3584 PF12128.8 CBK22021.2 - 0.00071 17.3 7.6 0.00093 16.9 7.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) DUF677 PF05055.12 CBK22021.2 - 0.00088 18.3 2.0 0.0011 17.9 2.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF677) DHR10 PF18595.1 CBK22021.2 - 0.0031 17.6 4.8 0.0031 17.6 4.8 1.8 3 0 0 3 3 1 1 Designed helical repeat protein 10 domain TMF_TATA_bd PF12325.8 CBK22021.2 - 0.0039 17.4 7.6 0.1 12.8 4.3 2.3 1 1 1 2 2 2 2 TATA element modulatory factor 1 TATA binding HeLo PF14479.6 CBK22021.2 - 0.0058 16.5 4.9 0.007 16.2 4.9 1.2 1 0 0 1 1 1 1 Prion-inhibition and propagation Laminin_II PF06009.12 CBK22021.2 - 0.0063 16.5 7.2 0.083 12.9 2.5 2.8 1 1 2 3 3 3 2 Laminin Domain II AAA_13 PF13166.6 CBK22021.2 - 0.0065 15.2 6.8 0.011 14.4 6.8 1.5 1 1 0 1 1 1 1 AAA domain Spectrin PF00435.21 CBK22021.2 - 0.0067 16.9 7.9 0.032 14.7 6.2 2.3 1 1 1 2 2 2 1 Spectrin repeat WXG100 PF06013.12 CBK22021.2 - 0.0071 16.6 3.9 0.3 11.3 0.9 3.4 1 1 0 2 2 2 1 Proteins of 100 residues with WXG SOGA PF11365.8 CBK22021.2 - 0.0072 17.4 3.2 0.0072 17.4 3.2 1.8 2 0 0 2 2 1 1 Protein SOGA V-SNARE PF05008.15 CBK22021.2 - 0.0075 16.6 7.4 0.018 15.4 5.9 2.4 2 1 1 3 3 2 1 Vesicle transport v-SNARE protein N-terminus Prominin PF05478.11 CBK22021.2 - 0.0088 14.1 5.6 0.01 13.8 5.6 1.1 1 0 0 1 1 1 1 Prominin DUF4337 PF14235.6 CBK22021.2 - 0.011 15.8 1.7 0.011 15.8 1.7 1.5 2 0 0 2 2 1 0 Domain of unknown function (DUF4337) BLOC1_2 PF10046.9 CBK22021.2 - 0.012 15.9 9.5 1.3 9.3 3.2 3.4 2 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF724 PF05266.14 CBK22021.2 - 0.012 15.5 7.9 0.053 13.3 7.9 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF724) APG6_N PF17675.1 CBK22021.2 - 0.013 16.1 7.6 0.028 14.9 7.4 1.8 1 1 0 1 1 1 0 Apg6 coiled-coil region Lant_dehydr_C PF14028.6 CBK22021.2 - 0.014 14.9 0.5 0.016 14.8 0.5 1.2 1 0 0 1 1 1 0 Lantibiotic biosynthesis dehydratase C-term DUF1515 PF07439.11 CBK22021.2 - 0.017 15.1 2.3 0.26 11.3 0.1 2.4 1 1 0 2 2 2 0 Protein of unknown function (DUF1515) Occludin_ELL PF07303.13 CBK22021.2 - 0.018 15.8 7.2 0.21 12.3 3.1 2.9 2 1 1 3 3 3 0 Occludin homology domain SKA1 PF07160.12 CBK22021.2 - 0.021 14.7 7.8 1.8 8.4 3.2 2.6 1 1 1 2 2 2 0 Spindle and kinetochore-associated protein 1 Prefoldin_2 PF01920.20 CBK22021.2 - 0.023 14.6 10.2 1 9.4 0.2 3.2 3 1 0 3 3 3 0 Prefoldin subunit FlaC_arch PF05377.11 CBK22021.2 - 0.025 15.0 9.6 7.7 7.0 2.9 4.0 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) Prefoldin PF02996.17 CBK22021.2 - 0.026 14.4 4.7 1.5 8.7 0.9 2.9 2 1 1 3 3 2 0 Prefoldin subunit Jnk-SapK_ap_N PF09744.9 CBK22021.2 - 0.027 14.7 9.1 0.05 13.8 6.5 2.3 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 Plasmid_RAQPRD PF09686.10 CBK22021.2 - 0.029 14.6 2.2 0.06 13.6 1.5 1.9 1 1 0 1 1 1 0 Plasmid protein of unknown function (Plasmid_RAQPRD) TraF_2 PF13729.6 CBK22021.2 - 0.032 13.6 2.0 0.075 12.4 0.1 1.9 1 1 1 2 2 2 0 F plasmid transfer operon, TraF, protein Med9 PF07544.13 CBK22021.2 - 0.033 14.3 9.7 0.26 11.4 4.1 3.4 2 1 2 4 4 3 0 RNA polymerase II transcription mediator complex subunit 9 DUF5446 PF17522.2 CBK22021.2 - 0.035 14.3 6.8 0.18 12.0 1.3 3.3 3 1 0 4 4 3 0 Family of unknown function (DUF5446) Trimer_CC PF08954.11 CBK22021.2 - 0.039 13.5 0.2 0.039 13.5 0.2 2.6 3 1 0 3 3 2 0 Trimerisation motif CheZ PF04344.13 CBK22021.2 - 0.049 13.5 4.9 1.7 8.6 0.6 2.5 1 1 2 3 3 3 0 Chemotaxis phosphatase, CheZ TMPIT PF07851.13 CBK22021.2 - 0.05 12.9 9.3 0.052 12.8 8.4 1.5 1 1 0 1 1 1 0 TMPIT-like protein Atg14 PF10186.9 CBK22021.2 - 0.058 12.5 5.4 0.07 12.2 5.4 1.4 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 PRKG1_interact PF15898.5 CBK22021.2 - 0.069 14.1 7.8 0.58 11.1 3.3 2.8 1 1 2 3 3 3 0 cGMP-dependent protein kinase interacting domain Fib_alpha PF08702.10 CBK22021.2 - 0.07 13.3 13.4 0.12 12.6 10.6 2.1 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family V_ATPase_I PF01496.19 CBK22021.2 - 0.072 11.0 3.9 0.081 10.8 3.9 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Fez1 PF06818.15 CBK22021.2 - 0.076 13.5 8.3 0.095 13.1 8.3 1.2 1 0 0 1 1 1 0 Fez1 Sec34 PF04136.15 CBK22021.2 - 0.081 12.8 9.1 0.37 10.7 4.8 2.7 1 1 2 3 3 3 0 Sec34-like family DUF4200 PF13863.6 CBK22021.2 - 0.085 13.3 5.7 0.19 12.1 5.6 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4200) DUF948 PF06103.11 CBK22021.2 - 0.17 12.2 5.4 1.3 9.4 1.9 3.1 3 1 0 3 3 3 0 Bacterial protein of unknown function (DUF948) Uso1_p115_C PF04871.13 CBK22021.2 - 0.21 11.9 7.8 0.38 11.1 6.8 2.0 1 1 1 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region DUF4164 PF13747.6 CBK22021.2 - 0.26 11.6 4.6 0.42 10.9 1.5 2.6 1 1 2 3 3 2 0 Domain of unknown function (DUF4164) FapA PF03961.13 CBK22021.2 - 0.28 9.7 5.3 0.43 9.1 5.3 1.3 1 1 0 1 1 1 0 Flagellar Assembly Protein A ORF6C PF10552.9 CBK22021.2 - 0.29 11.2 4.5 10 6.3 0.0 3.2 3 1 1 4 4 3 0 ORF6C domain ABC_tran_CTD PF16326.5 CBK22021.2 - 0.3 11.4 3.2 1.9 8.8 0.8 2.8 2 1 1 3 3 2 0 ABC transporter C-terminal domain DUF2408 PF10303.9 CBK22021.2 - 0.3 11.6 6.3 1 9.9 6.2 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF2408) EMP24_GP25L PF01105.24 CBK22021.2 - 0.32 10.9 8.4 0.39 10.7 1.0 2.5 1 1 1 2 2 2 0 emp24/gp25L/p24 family/GOLD TSNAXIP1_N PF15739.5 CBK22021.2 - 0.33 11.4 7.9 0.29 11.5 5.3 2.0 2 1 0 2 2 2 0 Translin-associated factor X-interacting N-terminus YabA PF06156.13 CBK22021.2 - 0.33 11.6 7.6 0.5 11.0 4.5 2.6 2 1 2 4 4 2 0 Initiation control protein YabA DUF2203 PF09969.9 CBK22021.2 - 0.35 11.6 4.6 4.5 8.0 0.1 2.3 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) ATG16 PF08614.11 CBK22021.2 - 0.37 11.0 9.1 0.44 10.7 8.1 1.8 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) RecG_N PF17190.4 CBK22021.2 - 0.42 11.4 4.4 1.5 9.6 0.8 2.8 1 1 2 3 3 3 0 RecG N-terminal helical domain Tho2 PF11262.8 CBK22021.2 - 0.44 9.7 7.5 0.92 8.7 7.3 1.7 1 1 1 2 2 2 0 Transcription factor/nuclear export subunit protein 2 GCN5L1 PF06320.13 CBK22021.2 - 0.5 10.5 8.0 0.66 10.1 3.7 2.8 1 1 1 2 2 2 0 GCN5-like protein 1 (GCN5L1) LPP PF04728.13 CBK22021.2 - 0.56 10.6 4.3 1.5 9.2 0.2 3.0 1 1 1 2 2 2 0 Lipoprotein leucine-zipper CorA PF01544.18 CBK22021.2 - 0.59 9.4 8.2 1.9 7.7 5.7 2.1 1 1 0 2 2 2 0 CorA-like Mg2+ transporter protein NBD94 PF16830.5 CBK22021.2 - 0.68 10.4 6.7 0.6 10.5 0.2 2.9 2 1 1 3 3 2 0 Nucleotide-Binding Domain 94 of RH Arc_PepC_II PF06847.11 CBK22021.2 - 0.73 10.4 3.1 33 5.1 1.9 2.7 1 1 2 3 3 2 0 Archaeal Peptidase A24 C-terminus Type II DUF1690 PF07956.11 CBK22021.2 - 0.79 10.1 9.7 1 9.8 7.9 2.0 1 1 1 2 2 1 0 Protein of Unknown function (DUF1690) IFP_35_N PF07334.13 CBK22021.2 - 0.91 9.6 5.6 0.9 9.7 0.5 2.9 2 1 0 3 3 3 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus Nup54 PF13874.6 CBK22021.2 - 1.2 9.2 8.8 3.7 7.7 8.8 1.8 1 1 0 1 1 1 0 Nucleoporin complex subunit 54 DUF3450 PF11932.8 CBK22021.2 - 1.5 8.1 11.1 1.8 7.8 4.2 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) BST2 PF16716.5 CBK22021.2 - 2.8 8.6 9.2 11 6.7 3.6 2.9 1 1 1 2 2 2 0 Bone marrow stromal antigen 2 DivIC PF04977.15 CBK22021.2 - 3.2 7.6 6.1 2 8.2 0.1 2.8 2 1 1 3 3 2 0 Septum formation initiator XhlA PF10779.9 CBK22021.2 - 4.2 7.6 11.0 8.1 6.7 0.9 3.7 1 1 2 3 3 3 0 Haemolysin XhlA SHIPPO-rpt PF07004.12 CBK22022.2 - 0.00022 22.0 99.7 4.1 8.5 0.3 20.5 8 4 11 19 19 19 12 Sperm-tail PG-rich repeat GIY-YIG PF01541.24 CBK22023.2 - 1.3e-16 60.6 0.3 2e-16 60.0 0.2 1.4 1 1 0 1 1 1 1 GIY-YIG catalytic domain T5orf172 PF10544.9 CBK22023.2 - 0.0024 18.4 0.5 0.0029 18.1 0.5 1.3 1 1 0 1 1 1 1 T5orf172 domain MUG113 PF13455.6 CBK22023.2 - 0.043 14.5 0.2 0.061 14.0 0.2 1.4 1 1 0 1 1 1 0 Meiotically up-regulated gene 113 EF-hand_1 PF00036.32 CBK22024.2 - 1.2e-24 84.0 4.8 4.1e-07 29.1 0.2 5.2 5 0 0 5 5 5 4 EF hand EF-hand_6 PF13405.6 CBK22024.2 - 1.5e-24 83.8 3.5 1e-07 31.3 0.1 5.1 5 0 0 5 5 5 4 EF-hand domain EF-hand_7 PF13499.6 CBK22024.2 - 1.2e-22 80.2 1.0 1.6e-11 44.5 0.1 3.1 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_8 PF13833.6 CBK22024.2 - 2.2e-19 69.0 6.8 3.2e-09 36.5 0.1 4.5 3 2 2 5 5 5 3 EF-hand domain pair EF-hand_5 PF13202.6 CBK22024.2 - 5.1e-17 60.5 8.2 0.00016 21.0 0.4 5.2 5 0 0 5 5 5 4 EF hand SPARC_Ca_bdg PF10591.9 CBK22024.2 - 0.0011 19.3 0.1 0.87 9.9 0.0 2.3 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_10 PF14788.6 CBK22024.2 - 0.0058 16.5 0.3 2.3 8.1 0.0 3.1 3 0 0 3 3 3 1 EF hand EF-hand_14 PF17959.1 CBK22024.2 - 0.018 15.4 0.9 9.3 6.7 0.1 3.5 3 2 1 4 4 4 0 EF-hand domain EF-hand_4 PF12763.7 CBK22024.2 - 0.021 14.7 1.5 6.1 6.8 0.2 3.6 1 1 1 3 3 3 0 Cytoskeletal-regulatory complex EF hand Caleosin PF05042.13 CBK22024.2 - 0.073 13.0 2.5 0.78 9.7 0.2 3.0 2 1 1 3 3 3 0 Caleosin related protein C2 PF00168.30 CBK22025.2 - 7.5e-11 42.2 0.1 9.2e-11 42.0 0.1 1.1 1 0 0 1 1 1 1 C2 domain DAO PF01266.24 CBK22026.2 - 8.5e-35 121.0 0.0 1.2e-34 120.4 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO_C PF16901.5 CBK22026.2 - 2e-33 114.9 0.1 3.8e-33 114.0 0.1 1.5 1 0 0 1 1 1 1 C-terminal domain of alpha-glycerophosphate oxidase 2TM PF13239.6 CBK22028.2 - 0.0043 17.3 0.5 0.0048 17.2 0.5 1.1 1 0 0 1 1 1 1 2TM domain Pkinase PF00069.25 CBK22029.2 - 2.9e-51 174.4 0.1 3.2e-50 170.9 0.1 2.2 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBK22029.2 - 4.1e-28 98.4 0.0 2.1e-23 83.0 0.0 2.3 2 1 0 2 2 2 2 Protein tyrosine kinase Haspin_kinase PF12330.8 CBK22029.2 - 0.00076 18.5 0.1 0.0011 18.0 0.1 1.3 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 CBK22029.2 - 0.014 14.7 0.1 0.026 13.8 0.0 1.5 2 0 0 2 2 2 0 Kinase-like APH PF01636.23 CBK22029.2 - 0.063 13.2 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family RIO1 PF01163.22 CBK22029.2 - 0.11 12.1 0.0 0.21 11.2 0.0 1.4 1 0 0 1 1 1 0 RIO1 family Kdo PF06293.14 CBK22029.2 - 0.15 11.4 0.1 0.3 10.4 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Thioredoxin PF00085.20 CBK22030.2 - 1.8e-16 60.0 0.1 3.9e-16 58.9 0.1 1.5 1 0 0 1 1 1 1 Thioredoxin OST3_OST6 PF04756.13 CBK22030.2 - 7.8e-05 22.2 0.0 0.00013 21.4 0.0 1.3 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family AhpC-TSA PF00578.21 CBK22030.2 - 0.00022 21.2 0.1 0.00045 20.1 0.1 1.5 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_8 PF13905.6 CBK22030.2 - 0.0022 18.3 0.2 0.016 15.6 0.1 2.5 2 1 1 3 3 3 1 Thioredoxin-like Thioredoxin_2 PF13098.6 CBK22030.2 - 0.011 16.2 2.1 0.012 16.1 0.1 2.1 2 0 0 2 2 2 0 Thioredoxin-like domain CAP_N PF01213.19 CBK22030.2 - 0.017 14.6 4.4 0.028 13.9 4.4 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Thioredoxin_7 PF13899.6 CBK22030.2 - 0.039 14.1 0.3 0.12 12.6 0.2 1.9 2 0 0 2 2 2 0 Thioredoxin-like TraF PF13728.6 CBK22030.2 - 0.64 9.8 0.0 0.64 9.8 0.0 2.8 3 0 0 3 3 3 0 F plasmid transfer operon protein CDC27 PF09507.10 CBK22030.2 - 1.6 8.1 16.0 2.2 7.6 16.0 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Mito_carr PF00153.27 CBK22031.2 - 6e-07 29.3 0.1 6.5e-07 29.2 0.1 1.0 1 0 0 1 1 1 1 Mitochondrial carrier protein Fibrinogen_aC PF12160.8 CBK22031.2 - 0.12 12.3 0.6 0.23 11.3 0.6 1.5 1 1 1 2 2 2 0 Fibrinogen alpha C domain LAP1C PF05609.12 CBK22032.2 - 0.0069 15.5 12.8 0.0089 15.2 12.8 1.1 1 0 0 1 1 1 1 Lamina-associated polypeptide 1C (LAP1C) Hid1 PF12722.7 CBK22032.2 - 0.1 10.7 15.9 0.12 10.5 15.9 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein GREB1 PF15782.5 CBK22032.2 - 0.12 9.5 9.9 0.14 9.3 9.9 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer DUF3675 PF12428.8 CBK22032.2 - 0.16 12.6 0.0 0.16 12.6 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3675) Caldesmon PF02029.15 CBK22032.2 - 0.4 9.4 43.1 0.5 9.1 43.1 1.0 1 0 0 1 1 1 0 Caldesmon FliP PF00813.20 CBK22032.2 - 0.45 10.4 12.9 0.38 10.6 6.8 2.2 1 1 1 2 2 2 0 FliP family DUF5383 PF17355.2 CBK22032.2 - 0.82 10.0 28.0 1 9.7 15.7 2.5 1 1 1 2 2 2 0 Family of unknown function (DUF5383) LMBR1 PF04791.16 CBK22032.2 - 2.7 6.8 14.1 3.5 6.4 14.1 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein MMR1 PF08505.10 CBK22032.2 - 9.4 6.4 24.8 12 6.1 24.8 1.1 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein Peptidase_C1 PF00112.23 CBK22033.2 - 1.6e-87 293.2 21.6 1.3e-46 159.4 7.5 2.0 2 0 0 2 2 2 2 Papain family cysteine protease Peptidase_C1_2 PF03051.15 CBK22033.2 - 0.00019 20.3 7.1 0.0044 15.8 0.8 2.3 2 0 0 2 2 2 2 Peptidase C1-like family SNF2_N PF00176.23 CBK22034.2 - 5.7e-58 196.3 0.2 2.3e-57 194.3 0.1 1.8 1 1 1 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 CBK22034.2 - 4.6e-20 72.0 0.0 2.4e-19 69.7 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 CBK22034.2 - 4.8e-08 33.2 0.0 1.3e-07 31.8 0.0 1.7 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit SWI2_SNF2 PF18766.1 CBK22034.2 - 0.00071 19.3 0.0 0.0013 18.5 0.0 1.4 1 0 0 1 1 1 1 SWI2/SNF2 ATPase ERCC3_RAD25_C PF16203.5 CBK22034.2 - 0.0008 18.7 0.1 0.0016 17.7 0.1 1.5 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase HDA2-3 PF11496.8 CBK22034.2 - 0.005 16.0 0.6 0.033 13.3 0.6 2.0 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 Viral_helicase1 PF01443.18 CBK22034.2 - 0.026 14.3 0.0 0.048 13.4 0.0 1.5 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase CAF1 PF04857.20 CBK22035.2 - 1.4e-17 63.9 0.3 4.6e-08 32.6 0.0 2.2 2 0 0 2 2 2 2 CAF1 family ribonuclease SpoU_methylase PF00588.19 CBK22036.2 - 4.3e-28 98.3 0.1 5.7e-28 97.9 0.1 1.2 1 0 0 1 1 1 1 SpoU rRNA Methylase family G_path_suppress PF15991.5 CBK22036.2 - 6.7 6.8 6.6 11 6.1 6.6 1.2 1 0 0 1 1 1 0 G-protein pathway suppressor Hormone_6 PF00236.18 CBK22038.2 - 0.043 13.8 0.0 0.32 11.0 0.0 1.9 2 0 0 2 2 2 0 Glycoprotein hormone DUF2423 PF10338.9 CBK22039.2 - 0.032 14.5 0.4 0.063 13.5 0.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2423) bVLRF1 PF18826.1 CBK22040.2 - 3.9e-31 107.9 0.1 5e-31 107.6 0.1 1.1 1 0 0 1 1 1 1 bacteroidetes VLRF1 release factor S4 PF01479.25 CBK22041.2 - 2.3e-13 49.6 0.1 5.2e-13 48.5 0.1 1.7 1 0 0 1 1 1 1 S4 domain PseudoU_synth_2 PF00849.22 CBK22041.2 - 6.5e-11 42.6 0.0 2.2e-10 40.8 0.0 1.7 1 1 0 1 1 1 1 RNA pseudouridylate synthase RRM_2 PF04059.12 CBK22042.2 - 4.4e-08 33.2 0.0 5.1e-08 33.0 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif 2 RRM_1 PF00076.22 CBK22042.2 - 6.7e-07 29.0 0.0 1e-06 28.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Bromodomain PF00439.25 CBK22043.2 - 3.8e-19 68.5 0.0 5.1e-19 68.1 0.0 1.2 1 0 0 1 1 1 1 Bromodomain MoeA_C PF03454.15 CBK22043.2 - 0.12 12.5 0.0 0.19 11.9 0.0 1.3 1 0 0 1 1 1 0 MoeA C-terminal region (domain IV) UCH PF00443.29 CBK22044.2 - 6.9e-08 32.3 0.1 7.8e-08 32.1 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase FGGY_N PF00370.21 CBK22045.2 - 2.9e-53 180.9 0.0 5.4e-15 55.6 0.0 4.5 2 2 2 4 4 4 4 FGGY family of carbohydrate kinases, N-terminal domain FGGY_C PF02782.16 CBK22045.2 - 3.6e-30 105.2 0.0 9.3e-16 58.1 0.0 2.6 2 0 0 2 2 2 2 FGGY family of carbohydrate kinases, C-terminal domain CDT1 PF08839.11 CBK22045.2 - 0.05 13.9 0.0 17 5.7 0.0 2.3 2 0 0 2 2 2 0 DNA replication factor CDT1 like LepB_GAP_N PF18172.1 CBK22045.2 - 0.1 12.5 0.0 16 5.3 0.0 3.1 3 1 1 4 4 4 0 LepB GAP domain N-terminal subdomain MOR2-PAG1_mid PF14228.6 CBK22045.2 - 0.11 10.1 0.1 6.2 4.3 0.0 2.0 2 0 0 2 2 2 0 Cell morphogenesis central region HECT PF00632.25 CBK22046.2 - 1.6e-58 198.6 0.0 2.2e-58 198.2 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) adh_short_C2 PF13561.6 CBK22047.2 - 4.8e-62 209.6 0.0 5.5e-62 209.4 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 CBK22047.2 - 1.8e-15 57.0 0.0 2.5e-15 56.5 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase Troponin PF00992.20 CBK22048.2 - 0.0012 19.1 0.2 0.0012 19.1 0.2 4.3 2 1 1 4 4 4 1 Troponin DUF2046 PF09755.9 CBK22048.2 - 0.02 14.1 1.3 0.02 14.1 1.3 3.4 2 1 0 3 3 3 0 Uncharacterized conserved protein H4 (DUF2046) APG6_N PF17675.1 CBK22048.2 - 0.031 14.8 4.4 0.031 14.8 4.4 4.7 3 1 1 4 4 4 0 Apg6 coiled-coil region T7SS_ESX_EspC PF10824.8 CBK22048.2 - 0.073 13.5 2.5 1.2 9.7 0.3 3.5 3 1 0 3 3 3 0 Excreted virulence factor EspC, type VII ESX diderm DASH_Dam1 PF08653.10 CBK22048.2 - 0.11 12.3 6.2 0.11 12.3 1.3 3.4 3 0 0 3 3 3 0 DASH complex subunit Dam1 DUF1664 PF07889.12 CBK22048.2 - 0.22 11.6 18.8 1.4 9.0 0.3 4.2 3 1 1 4 4 4 0 Protein of unknown function (DUF1664) CENP-F_leu_zip PF10473.9 CBK22048.2 - 0.78 9.8 52.8 1 9.4 19.2 5.1 3 1 1 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF724 PF05266.14 CBK22048.2 - 6.8 6.5 28.9 2.1 8.1 2.8 3.6 3 1 0 3 3 3 0 Protein of unknown function (DUF724) Ras PF00071.22 CBK22050.2 - 3.3e-57 192.6 0.1 6e-57 191.8 0.1 1.4 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CBK22050.2 - 3.7e-35 120.7 0.0 7.7e-35 119.7 0.0 1.6 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CBK22050.2 - 4.2e-13 49.1 0.1 6e-13 48.6 0.1 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 CBK22050.2 - 1.5e-06 27.8 0.0 3.2e-06 26.7 0.0 1.6 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 CBK22050.2 - 2.1e-06 27.3 0.1 2.9e-06 26.8 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_7 PF12775.7 CBK22050.2 - 0.0017 17.9 0.0 0.0031 17.0 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region MMR_HSR1 PF01926.23 CBK22050.2 - 0.005 16.9 0.0 0.012 15.7 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 CBK22050.2 - 0.0061 16.5 0.1 2.6 7.9 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase ABC_tran PF00005.27 CBK22050.2 - 0.028 14.9 0.0 0.057 13.9 0.0 1.5 1 1 0 1 1 1 0 ABC transporter TIR_2 PF13676.6 CBK22050.2 - 0.043 14.4 0.3 0.33 11.6 0.1 2.3 3 0 0 3 3 3 0 TIR domain AAA_16 PF13191.6 CBK22050.2 - 0.051 14.0 0.0 0.57 10.5 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain MMR_HSR1_Xtn PF16897.5 CBK22050.2 - 0.052 13.6 0.2 0.089 12.8 0.2 1.4 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain ResIII PF04851.15 CBK22050.2 - 0.063 13.3 0.0 0.1 12.6 0.0 1.5 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit BT1 PF03092.16 CBK22051.2 - 1.3e-14 53.3 8.3 1.5e-14 53.1 8.3 1.0 1 0 0 1 1 1 1 BT1 family MFS_1 PF07690.16 CBK22051.2 - 0.043 12.7 15.7 0.047 12.6 15.7 1.0 1 0 0 1 1 1 0 Major Facilitator Superfamily MFS_1_like PF12832.7 CBK22051.2 - 0.33 9.8 9.8 0.39 9.5 9.8 1.1 1 0 0 1 1 1 0 MFS_1 like family MORN PF02493.20 CBK22052.2 - 3.8e-05 23.3 14.5 0.54 10.3 2.3 4.8 5 0 0 5 5 5 3 MORN repeat DUF563 PF04577.14 CBK22053.2 - 7e-19 68.8 0.0 1.4e-18 67.8 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF563) DHHC PF01529.20 CBK22054.2 - 5.5e-26 91.3 9.7 5.5e-26 91.3 9.7 2.1 2 0 0 2 2 2 2 DHHC palmitoyltransferase DUF4239 PF14023.6 CBK22054.2 - 0.12 12.1 2.6 0.41 10.3 0.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF4239) Ank_2 PF12796.7 CBK22055.2 - 2e-29 102.0 13.0 2.9e-12 47.0 1.4 2.6 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CBK22055.2 - 7.6e-23 80.6 3.7 3.8e-10 40.1 0.1 3.9 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 CBK22055.2 - 4.3e-19 66.6 1.8 0.0016 18.8 0.0 4.3 4 0 0 4 4 4 4 Ankyrin repeat Ank PF00023.30 CBK22055.2 - 1e-18 66.9 6.8 4.5e-05 23.7 0.1 4.3 4 0 0 4 4 4 4 Ankyrin repeat Ank_5 PF13857.6 CBK22055.2 - 3e-18 65.6 6.6 1.2e-08 35.1 0.0 4.0 2 1 3 5 5 5 4 Ankyrin repeats (many copies) NOG1_N PF17835.1 CBK22056.2 - 1.8e-49 167.8 0.4 1.8e-49 167.8 0.4 2.1 2 0 0 2 2 2 1 NOG1 N-terminal helical domain NOG1 PF06858.14 CBK22056.2 - 1.2e-23 82.6 0.1 4e-23 81.0 0.0 2.0 2 0 0 2 2 2 1 Nucleolar GTP-binding protein 1 (NOG1) MMR_HSR1 PF01926.23 CBK22056.2 - 2.2e-16 60.0 0.0 4.9e-16 58.8 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase NOGCT PF08155.11 CBK22056.2 - 3.9e-16 58.8 4.4 9.3e-16 57.6 0.8 2.4 2 0 0 2 2 2 1 NOGCT (NUC087) domain FeoB_N PF02421.18 CBK22056.2 - 1.2e-07 31.4 0.0 2.1e-07 30.6 0.0 1.5 1 0 0 1 1 1 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 CBK22056.2 - 0.0013 18.7 0.1 0.27 11.1 0.0 3.3 3 1 0 3 3 3 1 RsgA GTPase Dynamin_N PF00350.23 CBK22056.2 - 0.012 15.7 0.9 5.9 6.9 0.0 3.1 2 1 1 3 3 3 0 Dynamin family AIG1 PF04548.16 CBK22056.2 - 0.013 14.8 0.0 0.026 13.9 0.0 1.5 1 0 0 1 1 1 0 AIG1 family Cnn_1N PF07989.11 CBK22056.2 - 0.21 11.7 8.1 0.087 13.0 5.1 2.0 2 0 0 2 2 2 0 Centrosomin N-terminal motif 1 OmpH PF03938.14 CBK22056.2 - 8.8 6.7 15.8 7.5 6.9 7.2 2.7 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) VWA_2 PF13519.6 CBK22057.2 - 0.13 13.0 0.0 0.28 11.8 0.0 1.6 1 0 0 1 1 1 0 von Willebrand factor type A domain Glyco_transf_49 PF13896.6 CBK22058.2 - 3.3e-08 33.3 1.1 4e-08 33.0 1.1 1.1 1 0 0 1 1 1 1 Glycosyl-transferase for dystroglycan Arm PF00514.23 CBK22059.2 - 5e-12 45.4 41.1 0.03 14.4 0.0 22.8 26 0 0 26 26 26 5 Armadillo/beta-catenin-like repeat Las1 PF04031.13 CBK22059.2 - 0.0016 18.6 0.1 0.098 12.8 0.0 3.9 2 0 0 2 2 2 1 Las1-like tRNA_U5-meth_tr PF05958.11 CBK22060.2 - 3.2e-20 72.4 0.0 6.1e-20 71.5 0.0 1.4 1 0 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase Methyltransf_31 PF13847.6 CBK22060.2 - 1.3e-11 44.5 0.9 2.8e-11 43.5 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 CBK22060.2 - 7e-09 36.3 0.0 2.1e-08 34.7 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain zf-CCCH PF00642.24 CBK22060.2 - 3.9e-07 29.8 0.9 9.6e-07 28.6 0.9 1.7 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 CBK22060.2 - 5.8e-07 29.3 3.1 2e-06 27.7 3.1 2.0 1 0 0 1 1 1 1 Zinc finger domain MTS PF05175.14 CBK22060.2 - 1.6e-06 27.7 0.0 3.6e-06 26.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain zf-CCCH_4 PF18044.1 CBK22060.2 - 4.1e-06 26.5 2.2 4.1e-06 26.5 2.2 2.4 3 0 0 3 3 3 1 CCCH-type zinc finger Ubie_methyltran PF01209.18 CBK22060.2 - 5.4e-05 22.6 0.0 0.0001 21.8 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_4 PF02390.17 CBK22060.2 - 0.0001 21.9 0.0 0.0001 21.9 0.0 2.4 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_11 PF08241.12 CBK22060.2 - 0.0002 21.9 0.0 0.00072 20.2 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CBK22060.2 - 0.00083 20.1 0.0 0.0065 17.2 0.0 2.5 2 0 0 2 2 2 1 Methyltransferase domain Torus PF16131.5 CBK22060.2 - 0.0011 19.6 3.4 0.0011 19.6 3.4 2.5 1 1 1 2 2 2 1 Torus domain Presenilin PF01080.17 CBK22060.2 - 0.0024 16.7 2.7 0.0024 16.7 2.7 2.1 2 0 0 2 2 2 1 Presenilin PCMT PF01135.19 CBK22060.2 - 0.0028 17.5 0.0 0.0051 16.6 0.0 1.4 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) PrmA PF06325.13 CBK22060.2 - 0.0035 16.8 0.0 0.0035 16.8 0.0 2.1 2 0 0 2 2 1 1 Ribosomal protein L11 methyltransferase (PrmA) zf-CCCH_2 PF14608.6 CBK22060.2 - 0.0051 17.2 2.0 0.0051 17.2 2.0 2.1 2 0 0 2 2 1 1 RNA-binding, Nab2-type zinc finger Methyltransf_15 PF09445.10 CBK22060.2 - 0.02 14.5 0.0 0.044 13.4 0.0 1.6 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase Cons_hypoth95 PF03602.15 CBK22060.2 - 0.039 13.6 0.0 0.039 13.6 0.0 2.0 2 0 0 2 2 1 0 Conserved hypothetical protein 95 Methyltransf_18 PF12847.7 CBK22060.2 - 0.059 13.3 1.6 0.06 13.3 0.0 1.7 2 0 0 2 2 1 0 Methyltransferase domain AviRa PF11599.8 CBK22060.2 - 0.074 12.5 0.1 0.074 12.5 0.1 2.1 2 0 0 2 2 1 0 RRNA methyltransferase AviRa V_ATPase_I PF01496.19 CBK22060.2 - 0.3 9.0 5.4 0.44 8.4 5.4 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Mitofilin PF09731.9 CBK22060.2 - 0.56 9.0 17.7 0.78 8.5 17.7 1.2 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Dicty_REP PF05086.12 CBK22060.2 - 0.58 8.1 10.1 0.9 7.4 10.1 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Mucin PF01456.17 CBK22060.2 - 0.66 10.0 10.5 1.3 9.0 10.5 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein Hid1 PF12722.7 CBK22060.2 - 2.8 5.9 11.9 4.3 5.4 11.9 1.3 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein ECH_1 PF00378.20 CBK22061.2 - 1.1e-22 80.6 0.0 1.3e-22 80.4 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 CBK22061.2 - 6e-14 52.3 0.0 6.7e-14 52.1 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase LRR_4 PF12799.7 CBK22062.2 - 7.1e-13 48.5 9.9 0.0099 16.3 0.0 5.3 3 1 1 5 5 5 4 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 CBK22062.2 - 3.9e-09 35.8 18.6 0.93 9.7 0.1 9.2 10 0 0 10 10 10 4 Leucine Rich repeat LRR_8 PF13855.6 CBK22062.2 - 8.1e-05 22.3 8.8 0.26 11.1 0.2 5.3 3 1 2 5 5 5 2 Leucine rich repeat LRR_1 PF00560.33 CBK22062.2 - 0.00036 20.7 31.9 6.6 7.7 0.1 9.3 9 1 0 9 9 9 4 Leucine Rich Repeat Pkinase PF00069.25 CBK22063.2 - 2.4e-43 148.4 0.0 3.3e-43 148.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBK22063.2 - 5.6e-41 140.5 0.0 7.3e-41 140.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase FTA2 PF13095.6 CBK22063.2 - 0.00011 21.9 0.0 0.014 15.1 0.0 2.2 1 1 1 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Haspin_kinase PF12330.8 CBK22063.2 - 0.00073 18.6 1.9 0.011 14.7 0.7 2.3 2 1 0 2 2 2 1 Haspin like kinase domain APH PF01636.23 CBK22063.2 - 0.014 15.3 0.1 0.036 14.0 0.1 1.4 1 1 0 1 1 1 0 Phosphotransferase enzyme family UEV PF05743.13 CBK22063.2 - 0.041 13.7 0.0 0.078 12.8 0.0 1.5 1 0 0 1 1 1 0 UEV domain DUF1939 PF09154.10 CBK22063.2 - 0.074 13.2 0.0 0.16 12.2 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1939) Kdo PF06293.14 CBK22063.2 - 0.075 12.4 0.1 0.14 11.5 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family He_PIG PF05345.12 CBK22064.2 - 1.2e-39 134.3 52.8 2.8e-08 33.8 1.6 7.7 6 0 0 6 6 6 6 Putative Ig domain F5_F8_type_C PF00754.25 CBK22064.2 - 9.9e-09 35.4 10.7 7.9e-05 22.8 0.4 4.2 4 0 0 4 4 4 2 F5/8 type C domain DUF4834 PF16118.5 CBK22064.2 - 0.068 14.1 0.0 0.17 12.8 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) CBM-like PF14683.6 CBK22064.2 - 0.15 11.9 1.9 11 5.9 0.0 3.4 3 0 0 3 3 3 0 Polysaccharide lyase family 4, domain III Ac76 PF05814.11 CBK22064.2 - 0.22 11.5 0.9 0.47 10.5 0.9 1.4 1 0 0 1 1 1 0 Orf76 (Ac76) Hydin_ADK PF17213.3 CBK22065.2 - 0.33 11.2 13.1 0.45 10.8 13.1 1.1 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain CSG2 PF16965.5 CBK22065.2 - 1.4 7.8 13.9 1.6 7.6 13.9 1.1 1 0 0 1 1 1 0 Ceramide synthase regulator DDHD PF02862.17 CBK22065.2 - 1.5 8.9 11.1 1.6 8.8 11.1 1.1 1 0 0 1 1 1 0 DDHD domain Gln-synt_N_2 PF16952.5 CBK22065.2 - 1.7 8.5 5.9 10 6.0 0.4 2.2 1 1 1 2 2 2 0 Glutamine synthetase N-terminal domain LicD PF04991.13 CBK22065.2 - 2.4 8.3 13.0 2.9 7.9 13.0 1.1 1 0 0 1 1 1 0 LicD family zf-RING_9 PF13901.6 CBK22065.2 - 3.3 7.6 13.7 4.3 7.3 13.7 1.2 1 0 0 1 1 1 0 Putative zinc-RING and/or ribbon Glyco_transf_41 PF13844.6 CBK22065.2 - 6 5.2 20.2 7.2 4.9 20.2 1.0 1 0 0 1 1 1 0 Glycosyl transferase family 41 Presenilin PF01080.17 CBK22065.2 - 6.2 5.5 13.9 6 5.5 13.9 1.1 1 0 0 1 1 1 0 Presenilin Forkhead_N PF08430.12 CBK22065.2 - 10 6.8 70.4 9.7e+02 0.3 70.4 2.1 1 1 0 1 1 1 0 Forkhead N-terminal region SNF2_N PF00176.23 CBK22066.2 - 4.2e-60 203.3 5.0 5.4e-60 203.0 2.0 2.0 1 1 1 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 CBK22066.2 - 8.8e-21 74.3 0.0 1e-19 70.9 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 CBK22066.2 - 2.2e-09 37.6 0.0 6.8e-09 36.0 0.0 1.9 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 CBK22066.2 - 8.1e-08 32.2 0.0 1.6e-07 31.2 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Chromo PF00385.24 CBK22066.2 - 1.1e-05 25.2 2.3 9.2e-05 22.3 2.3 2.6 1 1 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain TrwB_AAD_bind PF10412.9 CBK22066.2 - 0.11 11.4 0.8 11 4.8 0.0 2.6 3 0 0 3 3 3 0 Type IV secretion-system coupling protein DNA-binding domain Glyco_hydro_3_C PF01915.22 CBK22068.2 - 3e-39 135.1 0.0 4.3e-39 134.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 CBK22068.2 - 1.1e-35 123.5 0.0 1.6e-35 123.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 CBK22068.2 - 4.4e-12 45.9 0.1 1.1e-11 44.6 0.1 1.7 1 0 0 1 1 1 1 Fibronectin type III-like domain Peptidase_M16_C PF05193.21 CBK22069.2 - 9.9e-26 90.9 0.0 4.6e-25 88.7 0.0 2.1 3 0 0 3 3 3 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 CBK22069.2 - 8.3e-20 71.3 0.0 1.6e-19 70.3 0.0 1.5 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) PseudoU_synth_2 PF00849.22 CBK22070.2 - 1e-22 80.9 0.0 1.4e-22 80.5 0.0 1.3 1 0 0 1 1 1 1 RNA pseudouridylate synthase Hydrolase_6 PF13344.6 CBK22071.2 - 2.3e-31 107.9 0.0 3.9e-31 107.1 0.0 1.4 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 CBK22071.2 - 2.8e-09 36.9 0.0 6.1e-09 35.8 0.0 1.6 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.26 CBK22071.2 - 7.2e-05 23.2 0.0 0.0014 19.0 0.0 2.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase PGP_phosphatase PF09419.10 CBK22071.2 - 0.00051 19.7 0.0 0.00096 18.8 0.0 1.4 1 0 0 1 1 1 1 Mitochondrial PGP phosphatase Acid_phosphat_B PF03767.14 CBK22071.2 - 0.00063 19.4 0.0 0.00096 18.8 0.0 1.2 1 0 0 1 1 1 1 HAD superfamily, subfamily IIIB (Acid phosphatase) HAD_2 PF13419.6 CBK22071.2 - 0.018 15.2 0.0 1 9.4 0.0 2.2 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase DUF5330 PF17264.2 CBK22071.2 - 0.072 13.1 0.0 0.14 12.2 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5330) Peptidase_M22 PF00814.25 CBK22072.2 - 9.7e-86 287.8 0.0 1.2e-85 287.5 0.0 1.0 1 0 0 1 1 1 1 Glycoprotease family Carbam_trans_N PF02543.15 CBK22072.2 - 0.068 12.8 0.0 0.63 9.6 0.0 2.1 2 0 0 2 2 2 0 Carbamoyltransferase N-terminus He_PIG PF05345.12 CBK22076.2 - 3.7e-16 59.0 39.9 1.4e-05 25.1 6.4 5.4 4 1 0 4 4 4 3 Putative Ig domain BetaGal_dom4_5 PF13364.6 CBK22076.2 - 2.1e-06 28.3 1.4 0.00016 22.2 0.3 2.9 2 0 0 2 2 2 1 Beta-galactosidase jelly roll domain I-set PF07679.16 CBK22076.2 - 0.00026 21.0 2.5 3.8 7.6 0.0 5.1 5 0 0 5 5 5 1 Immunoglobulin I-set domain Orf78 PF06024.12 CBK22076.2 - 0.021 15.1 0.6 0.043 14.1 0.6 1.4 1 0 0 1 1 1 0 Orf78 (ac78) Shisa PF13908.6 CBK22076.2 - 0.023 15.0 1.8 0.069 13.4 1.8 1.8 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator F5_F8_type_C PF00754.25 CBK22076.2 - 0.026 14.7 18.1 0.16 12.1 0.1 5.0 5 1 0 5 5 4 0 F5/8 type C domain EphA2_TM PF14575.6 CBK22076.2 - 0.041 14.8 1.2 0.078 13.9 1.2 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain OAD_gamma PF04277.13 CBK22076.2 - 0.055 14.1 5.5 0.11 13.1 5.5 1.4 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain Baculo_11_kDa PF06143.11 CBK22076.2 - 0.066 12.8 3.2 0.13 11.8 3.2 1.4 1 0 0 1 1 1 0 Baculovirus 11 kDa family DUF5305 PF17231.2 CBK22076.2 - 0.085 12.3 2.2 0.22 10.9 2.2 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5305) OSTbeta PF15048.6 CBK22076.2 - 0.22 11.7 0.5 0.45 10.7 0.5 1.4 1 0 0 1 1 1 0 Organic solute transporter subunit beta protein TMEM154 PF15102.6 CBK22076.2 - 0.95 9.4 7.8 0.064 13.2 1.9 2.0 2 0 0 2 2 2 0 TMEM154 protein family DUF5385 PF17359.2 CBK22076.2 - 1 8.9 2.7 1.6 8.2 2.7 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5385) RIFIN PF02009.16 CBK22076.2 - 2.4 8.0 4.4 5.7 6.7 4.4 1.5 1 0 0 1 1 1 0 Rifin ASFV_J13L PF05568.11 CBK22076.2 - 8 6.2 9.8 2.4 7.9 5.7 2.3 2 0 0 2 2 1 0 African swine fever virus J13L protein ECSCR PF15820.5 CBK22076.2 - 9 6.2 8.2 1.3 8.9 3.4 2.0 2 0 0 2 2 2 0 Endothelial cell-specific chemotaxis regulator HCO3_cotransp PF00955.21 CBK22077.2 - 1.9e-23 83.1 0.5 2.6e-23 82.7 0.5 1.2 1 0 0 1 1 1 1 HCO3- transporter family SAM_2 PF07647.17 CBK22077.2 - 0.00058 19.9 0.0 0.0015 18.6 0.0 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) HCO3_cotransp PF00955.21 CBK22078.2 - 4.9e-35 121.3 0.9 8.1e-34 117.3 0.1 2.1 1 1 1 2 2 2 2 HCO3- transporter family WD40 PF00400.32 CBK22079.2 - 2.8e-15 56.5 7.8 0.00024 21.8 0.0 5.8 5 1 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBK22079.2 - 5.9e-08 32.9 3.4 0.063 13.6 0.0 4.0 2 2 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 CBK22079.2 - 0.047 12.6 1.3 2.1 7.2 0.1 2.7 3 1 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Collagen_bind_2 PF12904.7 CBK22079.2 - 0.13 12.3 0.3 2.2 8.4 0.0 2.5 1 1 1 2 2 2 0 Putative collagen-binding domain of a collagenase He_PIG PF05345.12 CBK22080.2 - 6.9e-17 61.4 40.1 1.3e-05 25.3 5.9 5.3 4 1 0 4 4 4 3 Putative Ig domain BetaGal_dom4_5 PF13364.6 CBK22080.2 - 2.1e-06 28.3 1.4 0.00016 22.2 0.3 2.9 2 0 0 2 2 2 1 Beta-galactosidase jelly roll domain I-set PF07679.16 CBK22080.2 - 0.0002 21.4 2.7 2.6 8.2 0.0 5.1 5 0 0 5 5 5 1 Immunoglobulin I-set domain F5_F8_type_C PF00754.25 CBK22080.2 - 0.0066 16.6 17.9 0.16 12.1 0.1 5.5 5 1 1 6 6 5 3 F5/8 type C domain Shisa PF13908.6 CBK22080.2 - 0.024 14.9 1.7 0.072 13.3 1.7 1.8 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator Orf78 PF06024.12 CBK22080.2 - 0.033 14.5 1.1 0.068 13.5 1.1 1.4 1 0 0 1 1 1 0 Orf78 (ac78) EphA2_TM PF14575.6 CBK22080.2 - 0.041 14.8 1.2 0.078 13.9 1.2 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain OAD_gamma PF04277.13 CBK22080.2 - 0.055 14.1 5.5 0.11 13.1 5.5 1.4 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain Baculo_11_kDa PF06143.11 CBK22080.2 - 0.066 12.8 3.2 0.13 11.8 3.2 1.4 1 0 0 1 1 1 0 Baculovirus 11 kDa family DUF5305 PF17231.2 CBK22080.2 - 0.1 12.0 2.4 0.27 10.6 2.4 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5305) OSTbeta PF15048.6 CBK22080.2 - 0.22 11.6 0.5 0.45 10.7 0.5 1.4 1 0 0 1 1 1 0 Organic solute transporter subunit beta protein TMEM154 PF15102.6 CBK22080.2 - 0.76 9.7 7.9 0.049 13.5 2.0 2.0 2 0 0 2 2 2 0 TMEM154 protein family DUF5385 PF17359.2 CBK22080.2 - 1 8.9 2.7 1.6 8.2 2.7 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5385) RIFIN PF02009.16 CBK22080.2 - 1.1 9.1 3.3 2.5 7.9 3.3 1.5 1 0 0 1 1 1 0 Rifin ASFV_J13L PF05568.11 CBK22080.2 - 7.8 6.2 9.8 2.4 7.9 5.7 2.3 2 0 0 2 2 1 0 African swine fever virus J13L protein ECSCR PF15820.5 CBK22080.2 - 8.7 6.2 8.2 1.2 9.0 3.4 2.0 2 0 0 2 2 2 0 Endothelial cell-specific chemotaxis regulator Zip PF02535.22 CBK22082.2 - 3.9e-17 62.5 5.6 5e-17 62.1 5.6 1.1 1 0 0 1 1 1 1 ZIP Zinc transporter Pyr_redox_2 PF07992.14 CBK22083.2 - 3.6e-54 184.0 0.0 4.4e-54 183.7 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 CBK22083.2 - 2.8e-28 98.3 0.0 8.4e-27 93.6 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 CBK22083.2 - 6.9e-18 65.0 0.1 1.2e-14 54.7 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 CBK22083.2 - 5.2e-10 39.1 0.1 1.1e-06 28.1 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 CBK22083.2 - 3.3e-07 29.3 0.6 6.9e-05 21.7 0.2 2.4 3 0 0 3 3 3 2 HI0933-like protein DAO PF01266.24 CBK22083.2 - 1.7e-05 24.6 1.7 0.0096 15.5 0.4 2.6 2 1 0 3 3 3 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 CBK22083.2 - 4.3e-05 22.8 2.8 0.00022 20.4 2.7 2.0 2 0 0 2 2 2 1 FAD binding domain GIDA PF01134.22 CBK22083.2 - 7.6e-05 22.0 0.8 0.00027 20.2 0.8 1.9 1 1 0 1 1 1 1 Glucose inhibited division protein A K_oxygenase PF13434.6 CBK22083.2 - 0.00011 21.5 0.3 0.0005 19.3 0.0 2.0 2 1 1 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) FAD_oxidored PF12831.7 CBK22083.2 - 0.00026 20.5 0.9 0.00039 19.9 0.9 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 CBK22083.2 - 0.0089 15.3 0.2 0.016 14.5 0.2 1.3 1 0 0 1 1 1 1 Thi4 family AlaDh_PNT_C PF01262.21 CBK22083.2 - 0.014 14.7 0.0 0.2 10.9 0.0 2.1 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_8 PF13450.6 CBK22083.2 - 0.015 15.5 2.1 0.029 14.6 0.4 2.4 3 0 0 3 3 3 0 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 CBK22083.2 - 0.019 14.0 0.0 0.65 9.0 0.1 2.2 2 0 0 2 2 2 0 Lycopene cyclase protein PTAC PF06130.12 CBK22083.2 - 0.12 12.5 0.0 0.45 10.7 0.0 1.9 2 0 0 2 2 1 0 Phosphate propanoyltransferase DFP PF04127.15 CBK22084.2 - 2.3e-15 56.9 0.0 1.4e-06 28.3 0.0 2.1 2 0 0 2 2 2 2 DNA / pantothenate metabolism flavoprotein COMPASS-Shg1 PF05205.12 CBK22084.2 - 0.043 14.5 0.0 0.57 10.9 0.0 2.3 2 1 0 2 2 2 0 COMPASS (Complex proteins associated with Set1p) component shg1 ATP-synt_ab PF00006.25 CBK22084.2 - 0.15 11.7 0.0 0.24 11.0 0.0 1.3 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain RRM_1 PF00076.22 CBK22085.2 - 9.7e-19 67.0 0.0 1.7e-18 66.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF3752 PF12572.8 CBK22086.2 - 1.8e-05 25.3 0.8 3e-05 24.6 0.8 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3752) DUF4763 PF15960.5 CBK22086.2 - 0.014 14.7 0.4 0.017 14.4 0.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4763) MHB PF16525.5 CBK22086.2 - 0.022 15.0 0.1 0.059 13.6 0.1 1.7 1 1 0 1 1 1 0 Haemophore, haem-binding Seryl_tRNA_N PF02403.22 CBK22086.2 - 0.037 14.2 0.2 0.062 13.5 0.2 1.3 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain FTA4 PF13093.6 CBK22086.2 - 0.15 12.0 2.8 0.19 11.6 2.8 1.4 1 1 0 1 1 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 Snf7 PF03357.21 CBK22087.2 - 8.2e-12 45.1 7.0 9.9e-12 44.8 7.0 1.0 1 0 0 1 1 1 1 Snf7 PAP2 PF01569.21 CBK22088.2 - 1.2e-18 67.2 0.9 2e-18 66.4 0.9 1.3 1 0 0 1 1 1 1 PAP2 superfamily PAP2_3 PF14378.6 CBK22088.2 - 2.7e-05 23.9 5.9 5.5e-05 22.9 5.9 1.5 1 1 0 1 1 1 1 PAP2 superfamily Bacteriocin_IIc PF10439.9 CBK22088.2 - 3.8 7.7 7.3 1.5 9.0 2.0 2.2 1 1 1 2 2 2 0 Bacteriocin class II with double-glycine leader peptide E1_DerP2_DerF2 PF02221.15 CBK22089.2 - 1e-11 45.4 0.0 1.3e-11 45.0 0.0 1.1 1 0 0 1 1 1 1 ML domain Creatinase_N_2 PF16189.5 CBK22090.2 - 5.9e-45 153.3 0.0 5.8e-43 146.8 0.0 2.3 2 0 0 2 2 2 1 Creatinase/Prolidase N-terminal domain Peptidase_M24 PF00557.24 CBK22090.2 - 6.8e-41 140.3 0.0 9.7e-41 139.8 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 Creatinase_N PF01321.18 CBK22090.2 - 1.1e-24 87.5 0.0 4.5e-17 62.9 0.0 2.5 2 0 0 2 2 2 2 Creatinase/Prolidase N-terminal domain Peptidase_M24_C PF16188.5 CBK22090.2 - 8.5e-15 54.6 0.4 2.1e-14 53.3 0.4 1.7 1 0 0 1 1 1 1 C-terminal region of peptidase_M24 DUF5320 PF17253.2 CBK22090.2 - 0.12 13.4 1.2 8.3 7.5 1.2 2.5 1 1 0 1 1 1 0 Family of unknown function (DUF5320) Pkinase PF00069.25 CBK22091.2 - 1e-56 192.2 0.0 1.9e-56 191.4 0.0 1.4 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBK22091.2 - 6.7e-26 91.1 0.0 8.8e-26 90.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CBK22091.2 - 1.5e-06 27.7 0.0 2.5e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 CBK22091.2 - 0.00022 20.2 0.0 0.00034 19.5 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 CBK22091.2 - 0.00061 18.8 0.0 0.001 18.1 0.0 1.3 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 CBK22091.2 - 0.029 13.7 0.1 0.063 12.6 0.0 1.5 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family MT-A70 PF05063.14 CBK22092.2 - 0.012 15.5 0.0 0.019 14.9 0.0 1.3 1 0 0 1 1 1 0 MT-A70 AMP-binding PF00501.28 CBK22093.2 - 7.6e-73 245.5 0.0 1.7e-72 244.3 0.0 1.5 1 1 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 CBK22093.2 - 3.6e-06 27.9 0.6 9.6e-06 26.5 0.6 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain IF4E PF01652.18 CBK22094.2 - 7.9e-25 87.5 2.1 1.8e-24 86.3 2.1 1.5 1 1 0 1 1 1 1 Eukaryotic initiation factor 4E NHase_alpha PF02979.16 CBK22094.2 - 0.11 11.8 0.0 0.19 11.0 0.0 1.4 1 0 0 1 1 1 0 Nitrile hydratase, alpha chain DUF4131 PF13567.6 CBK22095.2 - 0.13 11.9 0.1 0.14 11.8 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) SET PF00856.28 CBK22096.2 - 5.5e-08 33.4 0.0 1.5e-07 31.9 0.0 1.3 1 1 0 1 1 1 1 SET domain TruB_N PF01509.18 CBK22097.2 - 0.00071 20.0 0.0 0.0023 18.3 0.0 1.9 1 1 0 1 1 1 1 TruB family pseudouridylate synthase (N terminal domain) Rdx PF10262.9 CBK22098.2 - 8.6e-06 25.9 1.2 1.3e-05 25.3 1.2 1.4 1 1 0 1 1 1 1 Rdx family PHD PF00628.29 CBK22099.2 - 2.4e-12 46.5 38.7 0.00018 21.3 6.8 3.4 2 1 1 3 3 3 3 PHD-finger zf-PHD-like PF15446.6 CBK22099.2 - 0.17 11.5 24.3 0.094 12.3 2.2 2.9 2 1 0 2 2 2 0 PHD/FYVE-zinc-finger like domain zf-RING-like PF08746.11 CBK22099.2 - 8.7 6.8 36.0 0.11 12.9 6.1 3.8 3 1 0 3 3 3 0 RING-like domain Histone PF00125.24 CBK22100.2 - 1.1e-16 61.4 0.0 1.2e-16 61.2 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Histone_H2A_C PF16211.5 CBK22100.2 - 2e-09 37.0 0.1 3.3e-09 36.3 0.1 1.3 1 0 0 1 1 1 1 C-terminus of histone H2A CBFD_NFYB_HMF PF00808.23 CBK22100.2 - 0.0013 19.0 0.0 0.0016 18.7 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Nas2_N PF18265.1 CBK22101.2 - 6.2e-13 48.5 0.0 7.9e-13 48.1 0.0 1.2 1 0 0 1 1 1 1 Nas2 N_terminal domain GCP_C_terminal PF04130.13 CBK22103.2 - 7.3e-25 88.1 3.5 9.2e-25 87.7 3.5 1.1 1 0 0 1 1 1 1 Gamma tubulin complex component C-terminal Sdh5 PF03937.16 CBK22104.2 - 3.2e-22 78.3 0.2 5.3e-22 77.6 0.2 1.4 1 0 0 1 1 1 1 Flavinator of succinate dehydrogenase Na_H_antiporter PF03553.14 CBK22105.2 - 2.8e-48 164.7 15.3 2.8e-48 164.7 15.3 2.2 1 1 0 2 2 2 1 Na+/H+ antiporter family Orf78 PF06024.12 CBK22105.2 - 0.12 12.6 0.2 35 4.8 0.1 3.0 2 0 0 2 2 2 0 Orf78 (ac78) ASF1_hist_chap PF04729.13 CBK22106.2 - 9.4e-55 184.8 0.1 1.2e-54 184.4 0.1 1.1 1 0 0 1 1 1 1 ASF1 like histone chaperone Pkinase PF00069.25 CBK22107.2 - 2.2e-60 204.2 0.0 3e-60 203.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBK22107.2 - 1.7e-28 99.6 0.0 2.2e-28 99.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase PH PF00169.29 CBK22107.2 - 2.1e-05 25.0 0.0 4.5e-05 23.9 0.0 1.6 1 0 0 1 1 1 1 PH domain Pkinase_fungal PF17667.1 CBK22107.2 - 0.0005 19.0 0.0 0.00077 18.4 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 CBK22107.2 - 0.0018 17.6 0.0 0.0039 16.6 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family PH_8 PF15409.6 CBK22107.2 - 0.045 14.0 0.0 0.11 12.8 0.0 1.6 2 0 0 2 2 2 0 Pleckstrin homology domain FTA2 PF13095.6 CBK22107.2 - 0.13 11.8 0.0 0.32 10.6 0.0 1.7 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Peptidase_C13 PF01650.18 CBK22108.2 - 2.4e-80 269.7 0.0 3.9e-80 269.0 0.0 1.3 1 0 0 1 1 1 1 Peptidase C13 family Peptidase_C13 PF01650.18 CBK22109.2 - 1.9e-76 257.0 0.0 3e-76 256.3 0.0 1.3 1 0 0 1 1 1 1 Peptidase C13 family DUF1764 PF08576.10 CBK22111.2 - 1.1e-14 55.1 0.6 1.2e-14 55.0 0.6 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF1764) Ferredoxin_N PF16947.5 CBK22111.2 - 0.1 12.7 0.0 0.12 12.5 0.0 1.1 1 0 0 1 1 1 0 N-terminal region of 4Fe-4S ferredoxin iron-sulfur binding zf-Tim10_DDP PF02953.15 CBK22112.2 - 3.2e-14 52.3 2.7 3.6e-14 52.2 2.7 1.0 1 0 0 1 1 1 1 Tim10/DDP family zinc finger DUF913 PF06025.12 CBK22113.2 - 0.13 11.2 1.2 0.14 11.1 1.2 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Hid1 PF12722.7 CBK22113.2 - 0.19 9.8 3.9 0.22 9.6 3.9 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Presenilin PF01080.17 CBK22113.2 - 0.34 9.6 5.0 0.42 9.3 5.0 1.2 1 0 0 1 1 1 0 Presenilin RNA_pol_3_Rpc31 PF11705.8 CBK22113.2 - 0.38 11.0 21.6 0.54 10.5 21.6 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Zip PF02535.22 CBK22113.2 - 0.42 9.8 3.4 0.51 9.5 3.4 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter PGA2 PF07543.12 CBK22113.2 - 0.52 10.3 18.6 0.19 11.7 15.6 1.8 1 1 0 1 1 1 0 Protein trafficking PGA2 Vfa1 PF08432.10 CBK22113.2 - 0.88 9.9 17.0 1.4 9.2 17.0 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Bax1-I PF01027.20 CBK22114.2 - 1.1e-20 74.3 14.7 1.4e-20 74.0 14.7 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 Tmemb_9 PF05434.11 CBK22114.2 - 0.61 10.0 2.5 1.1 9.2 2.5 1.4 1 0 0 1 1 1 0 TMEM9 DUF2070 PF09843.9 CBK22114.2 - 2.3 6.4 10.8 2.9 6.1 10.8 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) NUDIX PF00293.28 CBK22115.2 - 3.3e-05 24.0 0.0 0.00013 22.1 0.0 1.8 1 1 0 1 1 1 1 NUDIX domain ACPS PF01648.20 CBK22116.2 - 6.9e-18 64.8 0.0 9e-18 64.5 0.0 1.2 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily 4PPT_N PF17837.1 CBK22116.2 - 0.053 13.7 0.6 8.7 6.6 0.0 2.3 2 0 0 2 2 2 0 4'-phosphopantetheinyl transferase N-terminal domain Pkinase PF00069.25 CBK22117.2 - 8.1e-63 212.2 0.1 6.2e-54 183.1 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CBK22117.2 - 1.5e-31 109.6 0.1 9.9e-30 103.7 0.1 2.4 2 1 0 2 2 2 1 Protein tyrosine kinase Haspin_kinase PF12330.8 CBK22117.2 - 3.5e-07 29.5 0.0 5.7e-07 28.8 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 CBK22117.2 - 1.2e-05 25.3 0.0 0.00012 22.1 0.0 2.3 1 1 1 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.22 CBK22117.2 - 0.0018 17.9 0.1 0.0053 16.4 0.1 1.8 1 1 0 1 1 1 1 RIO1 family Kdo PF06293.14 CBK22117.2 - 0.007 15.7 0.3 0.012 15.0 0.3 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pox_ser-thr_kin PF05445.11 CBK22117.2 - 0.11 11.5 0.1 0.16 10.9 0.1 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Seadorna_VP7 PF07387.11 CBK22117.2 - 0.15 11.1 0.1 0.29 10.1 0.1 1.4 1 0 0 1 1 1 0 Seadornavirus VP7 Ras PF00071.22 CBK22118.2 - 1.1e-60 203.9 0.5 1.3e-60 203.7 0.5 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CBK22118.2 - 1.9e-34 118.4 0.1 3.6e-34 117.6 0.1 1.4 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CBK22118.2 - 2.7e-16 59.5 0.0 3e-16 59.3 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 CBK22118.2 - 2.8e-07 30.6 0.0 4.9e-07 29.8 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 CBK22118.2 - 7.6e-07 29.2 0.5 0.0092 15.9 0.2 2.2 1 1 0 2 2 2 2 RsgA GTPase Gtr1_RagA PF04670.12 CBK22118.2 - 9.7e-07 28.4 0.1 1.2e-06 28.1 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 CBK22118.2 - 0.00014 21.4 0.2 0.00038 20.1 0.1 1.7 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 CBK22118.2 - 0.00016 21.1 0.0 0.0002 20.8 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_16 PF13191.6 CBK22118.2 - 0.0015 18.9 0.0 0.0019 18.6 0.0 1.3 1 1 0 1 1 1 1 AAA ATPase domain ATP_bind_1 PF03029.17 CBK22118.2 - 0.0067 16.2 0.2 0.033 14.0 0.0 1.9 1 1 0 2 2 2 1 Conserved hypothetical ATP binding protein ABC_tran PF00005.27 CBK22118.2 - 0.01 16.3 0.0 0.033 14.7 0.0 1.8 1 1 0 1 1 1 0 ABC transporter AAA_22 PF13401.6 CBK22118.2 - 0.016 15.5 0.0 0.021 15.1 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_24 PF13479.6 CBK22118.2 - 0.034 13.9 0.1 0.051 13.3 0.1 1.5 1 1 0 1 1 1 0 AAA domain DAP3 PF10236.9 CBK22118.2 - 0.054 12.7 0.0 0.083 12.0 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 Septin PF00735.18 CBK22118.2 - 0.061 12.6 0.2 0.24 10.7 0.1 1.9 1 1 1 2 2 2 0 Septin MCM PF00493.23 CBK22118.2 - 0.062 12.4 0.0 0.1 11.7 0.0 1.4 1 0 0 1 1 1 0 MCM P-loop domain AAA_29 PF13555.6 CBK22118.2 - 0.078 12.7 0.0 0.16 11.7 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain FeoB_N PF02421.18 CBK22118.2 - 0.084 12.4 0.0 0.69 9.4 0.0 2.0 1 1 0 1 1 1 0 Ferrous iron transport protein B NACHT PF05729.12 CBK22118.2 - 0.099 12.6 0.0 0.15 12.0 0.0 1.2 1 0 0 1 1 1 0 NACHT domain G-alpha PF00503.20 CBK22118.2 - 0.14 11.3 1.3 6.7 5.8 0.3 2.7 1 1 1 2 2 2 0 G-protein alpha subunit TniB PF05621.11 CBK22118.2 - 0.17 11.3 0.0 0.3 10.5 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein AAA_5 PF07728.14 CBK22118.2 - 0.18 11.8 0.0 0.3 11.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) HECT PF00632.25 CBK22119.2 - 3.6e-44 151.5 0.0 5.7e-44 150.8 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) CAP_N PF01213.19 CBK22121.2 - 0.88 9.0 2.9 1.2 8.6 2.9 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal PRIMA1 PF16101.5 CBK22121.2 - 2 8.5 5.9 3.1 7.9 5.9 1.3 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 DNA_pol_B_2 PF03175.13 CBK22122.2 - 1.5e-17 63.6 12.5 5.3e-15 55.2 8.4 2.3 2 0 0 2 2 2 2 DNA polymerase type B, organellar and viral zf-C3HC4 PF00097.25 CBK22123.2 - 2.5e-08 33.6 9.0 4.9e-08 32.7 9.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 CBK22123.2 - 2.7e-08 33.5 10.3 4.3e-08 32.9 10.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 CBK22123.2 - 2.7e-07 30.6 9.2 5.1e-07 29.8 9.2 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.6 CBK22123.2 - 3.2e-07 30.2 5.6 3.2e-07 30.2 5.6 2.1 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 CBK22123.2 - 1.9e-06 27.6 13.2 3.4e-06 26.8 13.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 CBK22123.2 - 4.8e-06 26.3 8.3 1.2e-05 25.1 8.3 1.7 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 CBK22123.2 - 1.3e-05 25.1 10.8 2.5e-05 24.1 10.8 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 CBK22123.2 - 1.3e-05 25.4 14.2 2.2e-05 24.7 14.2 1.4 1 0 0 1 1 1 1 Ring finger domain zf-Nse PF11789.8 CBK22123.2 - 0.00025 20.8 6.7 0.00054 19.7 6.7 1.5 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_6 PF14835.6 CBK22123.2 - 0.28 11.1 5.0 0.56 10.1 5.0 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_10 PF16685.5 CBK22123.2 - 0.3 11.2 7.3 0.62 10.2 7.3 1.5 1 1 0 1 1 1 0 zinc RING finger of MSL2 Rad50_zn_hook PF04423.14 CBK22123.2 - 0.52 10.2 5.9 3.2 7.7 0.0 3.0 3 0 0 3 3 3 0 Rad50 zinc hook motif zf-rbx1 PF12678.7 CBK22123.2 - 0.56 10.5 10.4 1.3 9.4 10.4 1.6 1 0 0 1 1 1 0 RING-H2 zinc finger domain DnaJ PF00226.31 CBK22124.2 - 1.7e-22 79.3 0.8 1.7e-22 79.3 0.8 3.6 3 1 0 3 3 3 1 DnaJ domain TPR_1 PF00515.28 CBK22125.2 - 7.6e-16 57.2 0.1 0.00038 20.1 0.1 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 CBK22125.2 - 4.2e-11 42.1 0.7 0.0045 17.0 0.1 3.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.6 CBK22125.2 - 4.7e-09 35.8 0.0 0.00023 20.8 0.0 2.8 1 1 2 3 3 3 2 TPR repeat TPR_19 PF14559.6 CBK22125.2 - 2.2e-07 31.2 0.0 0.52 10.9 0.0 4.1 2 1 2 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.6 CBK22125.2 - 4.5e-07 29.6 0.2 0.0077 16.4 0.0 3.8 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.6 CBK22125.2 - 3.3e-05 24.1 1.7 1 9.7 0.0 4.0 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.6 CBK22125.2 - 0.00046 20.6 0.4 4 8.3 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.6 CBK22125.2 - 0.00062 20.0 0.0 0.23 11.9 0.0 2.8 2 1 0 2 2 2 1 Tetratricopeptide repeat DUF5113 PF17140.4 CBK22125.2 - 0.0012 18.7 0.1 0.002 18.0 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF5113) TPR_3 PF07720.12 CBK22125.2 - 0.0023 17.9 0.0 0.057 13.4 0.0 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 CBK22125.2 - 0.0082 16.9 1.9 10 7.2 0.0 4.7 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_16 PF13432.6 CBK22125.2 - 0.02 15.5 0.0 0.074 13.7 0.0 2.0 2 0 0 2 2 1 0 Tetratricopeptide repeat TPR_9 PF13371.6 CBK22125.2 - 0.034 14.3 0.0 0.077 13.2 0.0 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat MIT PF04212.18 CBK22125.2 - 0.06 13.4 0.7 0.48 10.5 0.5 2.3 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain TPR_7 PF13176.6 CBK22125.2 - 0.11 12.6 0.3 9.7 6.5 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat ANAPC3 PF12895.7 CBK22125.2 - 0.18 12.1 1.5 0.9 9.8 0.2 2.8 3 1 1 4 4 2 0 Anaphase-promoting complex, cyclosome, subunit 3 Glyco_transf_49 PF13896.6 CBK22126.2 - 1.9e-12 47.2 0.9 4.1e-07 29.6 0.1 2.1 1 1 1 2 2 2 2 Glycosyl-transferase for dystroglycan Adaptin_N PF01602.20 CBK22127.2 - 2.5e-121 405.8 9.6 2.9e-121 405.6 9.6 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 CBK22127.2 - 6.4e-61 205.1 10.4 2.8e-57 193.3 0.2 3.6 3 1 1 4 4 4 3 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 CBK22127.2 - 9.4e-17 61.2 3.9 1.7e-05 25.1 0.0 5.3 3 1 2 5 5 5 3 HEAT repeats HEAT PF02985.22 CBK22127.2 - 3.7e-08 33.0 10.6 0.73 10.3 0.0 7.6 7 0 0 7 7 7 3 HEAT repeat Cnd3 PF12719.7 CBK22127.2 - 7.9e-08 31.8 4.0 4.7e-05 22.7 0.3 2.4 2 0 0 2 2 2 2 Nuclear condensing complex subunits, C-term domain CLASP_N PF12348.8 CBK22127.2 - 0.00012 21.7 0.1 0.17 11.4 0.0 3.2 2 1 1 3 3 3 2 CLASP N terminal Arm PF00514.23 CBK22127.2 - 0.006 16.6 1.4 16 5.7 0.1 4.6 6 0 0 6 6 6 1 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 CBK22127.2 - 0.019 15.4 6.8 4.3 7.9 0.0 5.3 6 1 1 7 7 7 0 HEAT-like repeat HEAT_PBS PF03130.16 CBK22127.2 - 0.1 13.3 0.1 16 6.5 0.0 3.6 2 0 0 2 2 2 0 PBS lyase HEAT-like repeat DER1 PF04511.15 CBK22128.2 - 2.1e-16 60.4 2.6 2.4e-16 60.3 2.6 1.0 1 0 0 1 1 1 1 Der1-like family DUF3989 PF13150.6 CBK22128.2 - 0.048 13.4 0.0 0.17 11.6 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3989) Oleosin PF01277.17 CBK22128.2 - 0.13 12.0 1.5 0.25 11.1 1.5 1.5 1 0 0 1 1 1 0 Oleosin 4F5 PF04419.14 CBK22129.2 - 0.00022 22.0 5.9 0.00022 22.0 5.9 2.4 2 1 0 2 2 2 1 4F5 protein family tRNA-synt_1c PF00749.21 CBK22130.2 - 2.1e-76 256.8 0.0 2.5e-76 256.6 0.0 1.0 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1f PF01921.18 CBK22130.2 - 0.24 10.3 0.0 11 4.8 0.0 2.0 2 0 0 2 2 2 0 tRNA synthetases class I (K) Thioredoxin_7 PF13899.6 CBK22131.2 - 2.7e-10 40.3 0.1 3.8e-10 39.8 0.1 1.2 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.6 CBK22131.2 - 0.001 19.5 0.1 0.0012 19.2 0.1 1.3 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 CBK22131.2 - 0.012 15.9 0.2 0.034 14.5 0.1 1.9 1 1 1 2 2 2 0 Thioredoxin-like Glyco_hydro_38N PF01074.22 CBK22132.2 - 2.4e-09 37.0 0.0 4e-09 36.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_57 PF03065.15 CBK22132.2 - 0.051 12.8 0.0 0.066 12.4 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 57 XG_FTase PF03254.13 CBK22133.2 - 0.0074 15.0 0.0 0.026 13.2 0.0 1.7 2 0 0 2 2 2 1 Xyloglucan fucosyltransferase Troponin PF00992.20 CBK22134.2 - 0.032 14.5 1.9 0.06 13.6 1.9 1.4 1 0 0 1 1 1 0 Troponin DUF4286 PF14114.6 CBK22134.2 - 0.079 13.5 0.2 0.36 11.3 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4286) Lactamase_B_6 PF16661.5 CBK22135.2 - 2.5e-17 63.0 0.0 4.7e-17 62.1 0.0 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily domain Beta-Casp PF10996.8 CBK22135.2 - 4.8e-14 52.6 0.0 1.1e-13 51.4 0.0 1.7 1 0 0 1 1 1 1 Beta-Casp domain Lactamase_B_2 PF12706.7 CBK22135.2 - 3.3e-13 49.6 0.0 1.6e-12 47.4 0.0 2.1 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 CBK22135.2 - 2.1e-12 47.5 0.0 6.2e-10 39.4 0.0 2.6 3 0 0 3 3 3 2 Metallo-beta-lactamase superfamily RMMBL PF07521.12 CBK22135.2 - 2.1e-05 24.3 0.0 4.1e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain Lactamase_B_3 PF13483.6 CBK22135.2 - 0.00015 21.7 0.1 0.00053 19.9 0.1 1.8 1 1 0 1 1 1 1 Beta-lactamase superfamily domain PDEase_II PF02112.15 CBK22135.2 - 0.077 12.1 1.8 0.11 11.6 0.5 1.7 1 1 1 2 2 2 0 cAMP phosphodiesterases class-II DUF678 PF05077.12 CBK22136.2 - 0.071 13.3 0.2 0.071 13.3 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF678) Mito_fiss_reg PF05308.11 CBK22137.2 - 0.1 12.6 0.3 0.13 12.4 0.3 1.1 1 0 0 1 1 1 0 Mitochondrial fission regulator CAP_N PF01213.19 CBK22137.2 - 0.89 9.0 5.0 1.1 8.7 5.0 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal PRIMA1 PF16101.5 CBK22137.2 - 7.2 6.7 9.6 12 5.9 9.6 1.4 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 EF-hand_7 PF13499.6 CBK22138.2 - 2.2e-11 44.1 5.0 7e-08 32.8 0.3 2.2 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 CBK22138.2 - 4.7e-09 35.2 0.2 0.00056 19.3 0.0 2.6 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 CBK22138.2 - 7e-09 34.9 1.1 0.00022 20.9 0.0 3.1 2 1 1 3 3 3 2 EF-hand domain EF-hand_8 PF13833.6 CBK22138.2 - 1.5e-07 31.1 2.5 0.0023 17.7 0.1 3.1 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.6 CBK22138.2 - 0.013 14.9 0.1 1.3 8.6 0.0 2.5 2 0 0 2 2 2 0 EF hand FAM180 PF15173.6 CBK22138.2 - 0.18 11.8 0.1 0.22 11.5 0.1 1.2 1 0 0 1 1 1 0 FAM180 family Pkinase PF00069.25 CBK22139.2 - 1.7e-63 214.5 0.0 2.1e-63 214.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBK22139.2 - 7.6e-28 97.5 0.0 9.2e-28 97.2 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CBK22139.2 - 0.0001 21.2 0.0 0.00014 20.8 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 CBK22139.2 - 0.0053 16.1 0.0 0.0062 15.9 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 CBK22139.2 - 0.015 15.2 0.1 0.42 10.5 0.0 2.4 2 1 1 3 3 3 0 Phosphotransferase enzyme family AAA PF00004.29 CBK22140.2 - 7.1e-40 136.5 0.0 9.6e-40 136.1 0.0 1.2 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CBK22140.2 - 5.9e-07 29.2 0.0 1.1e-06 28.3 0.0 1.4 1 0 0 1 1 1 1 AAA+ lid domain RuvB_N PF05496.12 CBK22140.2 - 2.6e-05 24.0 0.0 5e-05 23.1 0.0 1.5 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 CBK22140.2 - 0.00011 22.5 0.5 0.00097 19.4 0.5 2.3 1 1 0 1 1 1 1 AAA domain AAA_2 PF07724.14 CBK22140.2 - 0.00013 22.2 0.1 0.0003 20.9 0.0 1.6 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_18 PF13238.6 CBK22140.2 - 0.00024 21.6 0.0 0.00041 20.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.14 CBK22140.2 - 0.00028 20.9 0.6 0.0018 18.3 0.6 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 CBK22140.2 - 0.00059 20.3 0.4 0.17 12.3 0.1 2.5 1 1 0 2 2 2 1 AAA ATPase domain DUF815 PF05673.13 CBK22140.2 - 0.00065 18.9 0.0 0.00095 18.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_25 PF13481.6 CBK22140.2 - 0.00074 19.1 0.5 0.17 11.5 0.1 2.3 1 1 0 2 2 2 1 AAA domain AAA_14 PF13173.6 CBK22140.2 - 0.0017 18.4 0.0 0.0033 17.5 0.0 1.5 2 0 0 2 2 1 1 AAA domain TniB PF05621.11 CBK22140.2 - 0.0029 17.0 0.1 2.8 7.3 0.0 2.4 1 1 0 2 2 2 2 Bacterial TniB protein TIP49 PF06068.13 CBK22140.2 - 0.0035 16.6 0.0 0.0046 16.2 0.0 1.2 1 0 0 1 1 1 1 TIP49 P-loop domain Mg_chelatase PF01078.21 CBK22140.2 - 0.011 15.1 0.1 0.022 14.2 0.1 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_24 PF13479.6 CBK22140.2 - 0.012 15.4 0.3 0.021 14.5 0.3 1.5 1 1 0 1 1 1 0 AAA domain AAA_7 PF12775.7 CBK22140.2 - 0.016 14.7 0.1 0.047 13.2 0.1 1.8 1 1 0 1 1 1 0 P-loop containing dynein motor region IstB_IS21 PF01695.17 CBK22140.2 - 0.017 14.9 0.0 0.027 14.2 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_33 PF13671.6 CBK22140.2 - 0.018 15.2 0.0 0.035 14.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 CBK22140.2 - 0.082 12.6 0.2 1.2 8.9 0.2 2.3 1 1 0 1 1 1 0 Sigma-54 interaction domain Guanylate_kin PF00625.21 CBK22140.2 - 0.16 11.6 0.1 0.39 10.4 0.0 1.6 2 0 0 2 2 2 0 Guanylate kinase AAA_19 PF13245.6 CBK22140.2 - 0.17 12.2 0.3 0.34 11.2 0.3 1.6 1 1 0 1 1 1 0 AAA domain ATPase PF06745.13 CBK22140.2 - 0.24 10.7 1.3 2 7.7 0.2 2.0 1 1 1 2 2 2 0 KaiC Ribosomal_L1 PF00687.21 CBK22141.2 - 5.9e-42 143.7 0.0 8e-42 143.3 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family DUF1935 PF09149.10 CBK22141.2 - 0.079 13.3 0.0 0.17 12.3 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1935) Ran_BP1 PF00638.18 CBK22142.2 - 1.7e-38 131.6 2.6 2.6e-38 131.0 2.6 1.3 1 0 0 1 1 1 1 RanBP1 domain WH1 PF00568.23 CBK22142.2 - 0.0015 18.4 0.4 0.0043 17.0 0.4 1.7 1 1 0 1 1 1 1 WH1 domain DUF1681 PF07933.14 CBK22142.2 - 0.0077 15.9 0.3 0.011 15.5 0.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1681) DUF563 PF04577.14 CBK22143.2 - 1.6e-20 74.2 1.7 7.4e-20 72.0 0.0 2.3 2 1 0 2 2 2 1 Protein of unknown function (DUF563) Collagen PF01391.18 CBK22144.2 - 9.2e-31 105.4 115.2 9.1e-09 35.0 27.9 4.3 1 1 3 4 4 4 4 Collagen triple helix repeat (20 copies) NUC153 PF08159.12 CBK22145.2 - 1.6e-10 40.6 2.8 8.4e-10 38.3 0.1 2.5 3 0 0 3 3 3 1 NUC153 domain DUF2026 PF09641.10 CBK22145.2 - 0.003 17.2 0.0 0.0033 17.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2026) Antirestrict PF03230.13 CBK22145.2 - 0.16 12.0 0.0 0.21 11.7 0.0 1.2 1 0 0 1 1 1 0 Antirestriction protein CDH1_2_SANT_HL1 PF18375.1 CBK22146.2 - 0.003 18.2 0.2 0.0055 17.4 0.2 1.4 1 0 0 1 1 1 1 CDH1/2 SANT-Helical linker 1 CDT1 PF08839.11 CBK22146.2 - 0.021 15.2 0.7 0.031 14.6 0.3 1.5 1 1 0 1 1 1 0 DNA replication factor CDT1 like Importin_rep_6 PF18829.1 CBK22146.2 - 0.024 14.8 0.3 0.053 13.7 0.2 1.6 2 0 0 2 2 2 0 Importin repeat 6 YtxH PF12732.7 CBK22146.2 - 0.028 15.0 0.1 0.088 13.3 0.1 1.9 1 1 0 1 1 1 0 YtxH-like protein RhoGAP PF00620.27 CBK22147.2 - 6.4e-23 81.3 0.1 8.6e-23 80.8 0.1 1.1 1 0 0 1 1 1 1 RhoGAP domain MORN PF02493.20 CBK22148.2 - 0.0023 17.7 17.8 0.097 12.6 0.4 5.6 6 0 0 6 6 6 3 MORN repeat DUF772 PF05598.11 CBK22148.2 - 0.011 15.7 0.1 0.024 14.7 0.1 1.5 1 0 0 1 1 1 0 Transposase domain (DUF772) GCFC PF07842.12 CBK22149.2 - 0.0014 18.4 0.0 0.23 11.0 0.0 2.8 3 0 0 3 3 3 2 GC-rich sequence DNA-binding factor-like protein PUF PF00806.19 CBK22150.2 - 4.1e-06 26.2 0.0 0.094 12.4 0.0 4.0 4 0 0 4 4 4 3 Pumilio-family RNA binding repeat AAA_25 PF13481.6 CBK22151.2 - 4e-24 85.3 0.0 4.6e-23 81.8 0.0 2.2 2 0 0 2 2 2 1 AAA domain DnaB_C PF03796.15 CBK22151.2 - 1.9e-10 40.6 0.0 2.9e-10 39.9 0.0 1.2 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain AAA_22 PF13401.6 CBK22151.2 - 3.6e-08 33.8 0.0 9.8e-08 32.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 CBK22151.2 - 3.8e-08 33.9 0.1 1.2e-07 32.3 0.1 1.9 1 0 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 CBK22151.2 - 0.00044 19.9 0.1 0.00098 18.8 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain T2SSE PF00437.20 CBK22151.2 - 0.00087 18.4 0.0 0.0014 17.7 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein ABC_tran PF00005.27 CBK22151.2 - 0.001 19.6 0.0 0.0028 18.2 0.0 1.7 1 0 0 1 1 1 1 ABC transporter AAA_23 PF13476.6 CBK22151.2 - 0.0036 17.8 2.9 0.0042 17.6 0.1 2.1 2 0 0 2 2 2 1 AAA domain cobW PF02492.19 CBK22151.2 - 0.0047 16.5 0.1 0.0078 15.8 0.1 1.3 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain NACHT PF05729.12 CBK22151.2 - 0.008 16.1 0.0 0.013 15.4 0.0 1.4 1 0 0 1 1 1 1 NACHT domain IstB_IS21 PF01695.17 CBK22151.2 - 0.013 15.2 0.0 0.026 14.3 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_28 PF13521.6 CBK22151.2 - 0.016 15.5 0.3 0.054 13.7 0.1 2.0 1 1 0 1 1 1 0 AAA domain ATPase PF06745.13 CBK22151.2 - 0.025 14.0 0.0 0.06 12.7 0.0 1.6 1 0 0 1 1 1 0 KaiC AAA_30 PF13604.6 CBK22151.2 - 0.032 13.9 2.1 0.066 12.9 0.0 2.2 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 CBK22151.2 - 0.041 13.8 0.1 0.081 12.8 0.1 1.5 1 0 0 1 1 1 0 NTPase AAA_14 PF13173.6 CBK22151.2 - 0.043 13.8 0.4 0.24 11.4 0.4 2.1 1 1 0 1 1 1 0 AAA domain AAA_18 PF13238.6 CBK22151.2 - 0.051 14.1 0.0 0.16 12.5 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_21 PF13304.6 CBK22151.2 - 0.053 13.3 0.1 0.093 12.5 0.1 1.4 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 CBK22151.2 - 0.055 13.4 0.1 0.13 12.1 0.1 1.6 1 0 0 1 1 1 0 RsgA GTPase PhoH PF02562.16 CBK22151.2 - 0.063 12.7 0.0 0.14 11.6 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein SRPRB PF09439.10 CBK22151.2 - 0.066 12.6 0.1 0.11 11.9 0.1 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit SRP54 PF00448.22 CBK22151.2 - 0.094 12.3 0.0 0.26 10.9 0.0 1.6 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain DAP3 PF10236.9 CBK22151.2 - 0.1 11.7 0.1 0.16 11.1 0.1 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 AAA_7 PF12775.7 CBK22151.2 - 0.12 11.9 0.1 0.59 9.6 0.0 1.9 2 0 0 2 2 2 0 P-loop containing dynein motor region APS_kinase PF01583.20 CBK22151.2 - 0.15 12.0 0.1 0.66 9.8 0.0 2.0 2 0 0 2 2 2 0 Adenylylsulphate kinase MORN PF02493.20 CBK22152.2 - 9.2e-08 31.6 0.4 0.0013 18.5 0.1 2.4 2 0 0 2 2 2 2 MORN repeat AAA PF00004.29 CBK22153.2 - 1.2e-41 142.3 0.0 4.4e-41 140.4 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) MIT PF04212.18 CBK22153.2 - 3.8e-18 65.3 0.9 5.9e-18 64.7 0.1 1.8 2 0 0 2 2 1 1 MIT (microtubule interacting and transport) domain Vps4_C PF09336.10 CBK22153.2 - 2.6e-15 56.2 0.0 1.4e-14 53.8 0.0 2.4 3 0 0 3 3 1 1 Vps4 C terminal oligomerisation domain AAA_lid_3 PF17862.1 CBK22153.2 - 6.1e-08 32.4 0.0 1.5e-07 31.1 0.0 1.6 1 0 0 1 1 1 1 AAA+ lid domain RuvB_N PF05496.12 CBK22153.2 - 9.7e-08 31.9 0.0 6.6e-06 25.9 0.0 2.4 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 CBK22153.2 - 4.2e-07 30.5 0.1 0.0034 17.8 0.0 2.9 2 1 1 3 3 2 2 AAA ATPase domain AAA_22 PF13401.6 CBK22153.2 - 5.4e-07 30.0 0.0 0.00027 21.2 0.0 2.6 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 CBK22153.2 - 1.1e-05 25.3 0.0 3e-05 23.8 0.0 1.7 2 0 0 2 2 1 1 IstB-like ATP binding protein AAA_5 PF07728.14 CBK22153.2 - 3.3e-05 23.9 0.0 0.00036 20.5 0.0 2.6 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) ATPase_2 PF01637.18 CBK22153.2 - 7.3e-05 22.8 0.1 0.21 11.5 0.0 2.7 2 1 1 3 3 3 2 ATPase domain predominantly from Archaea AAA_14 PF13173.6 CBK22153.2 - 0.00011 22.2 0.0 0.00027 21.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain DUF815 PF05673.13 CBK22153.2 - 0.00044 19.5 0.0 0.00076 18.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_2 PF07724.14 CBK22153.2 - 0.00073 19.7 0.0 0.005 17.0 0.0 2.3 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_18 PF13238.6 CBK22153.2 - 0.0011 19.5 0.0 0.0037 17.8 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_24 PF13479.6 CBK22153.2 - 0.002 17.9 0.5 0.008 15.9 0.0 2.2 3 0 0 3 3 2 1 AAA domain RNA_helicase PF00910.22 CBK22153.2 - 0.0022 18.4 0.0 0.0057 17.0 0.0 1.7 1 0 0 1 1 1 1 RNA helicase AAA_25 PF13481.6 CBK22153.2 - 0.0032 17.1 0.1 0.58 9.7 0.1 2.4 1 1 1 2 2 2 1 AAA domain AAA_33 PF13671.6 CBK22153.2 - 0.006 16.8 0.0 0.014 15.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.13 CBK22153.2 - 0.0065 15.7 0.0 0.027 13.7 0.0 1.9 2 0 0 2 2 2 1 TIP49 P-loop domain Bac_DnaA PF00308.18 CBK22153.2 - 0.008 16.0 0.0 0.095 12.5 0.0 2.2 1 1 0 1 1 1 1 Bacterial dnaA protein AAA_7 PF12775.7 CBK22153.2 - 0.016 14.8 0.0 0.053 13.0 0.0 1.9 1 1 0 1 1 1 0 P-loop containing dynein motor region ATPase PF06745.13 CBK22153.2 - 0.024 14.0 0.0 6.5 6.0 0.0 2.5 1 1 1 2 2 2 0 KaiC Sigma54_activat PF00158.26 CBK22153.2 - 0.032 13.9 0.0 0.18 11.5 0.0 2.3 2 1 0 2 2 2 0 Sigma-54 interaction domain Mg_chelatase PF01078.21 CBK22153.2 - 0.032 13.6 0.0 0.06 12.7 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI CPT PF07931.12 CBK22153.2 - 0.044 13.6 0.0 0.086 12.7 0.0 1.4 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein NRBF2_MIT PF17169.4 CBK22153.2 - 0.044 14.0 0.0 0.099 12.9 0.0 1.6 1 0 0 1 1 1 0 MIT domain of nuclear receptor-binding factor 2 KAP_NTPase PF07693.14 CBK22153.2 - 0.051 12.8 0.0 1.9 7.6 0.0 2.4 1 1 1 2 2 2 0 KAP family P-loop domain Viral_helicase1 PF01443.18 CBK22153.2 - 0.053 13.3 0.0 0.1 12.3 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Sigma54_activ_2 PF14532.6 CBK22153.2 - 0.07 13.2 0.0 0.24 11.5 0.0 1.9 2 0 0 2 2 1 0 Sigma-54 interaction domain Parvo_NS1 PF01057.17 CBK22153.2 - 0.078 12.1 0.0 0.15 11.1 0.0 1.4 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_21 PF13304.6 CBK22153.2 - 0.088 12.6 0.0 11 5.7 0.0 2.5 1 1 1 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system NACHT PF05729.12 CBK22153.2 - 0.097 12.6 0.0 1.1 9.2 0.0 2.3 1 1 1 2 2 2 0 NACHT domain AAA_17 PF13207.6 CBK22153.2 - 0.1 13.0 0.1 0.41 11.1 0.0 2.0 2 0 0 2 2 2 0 AAA domain AFG1_ATPase PF03969.16 CBK22153.2 - 0.11 11.3 0.0 0.18 10.7 0.0 1.3 1 0 0 1 1 1 0 AFG1-like ATPase AAA_30 PF13604.6 CBK22153.2 - 0.12 12.1 0.0 0.41 10.3 0.0 1.9 1 1 0 1 1 1 0 AAA domain PhoH PF02562.16 CBK22153.2 - 0.13 11.7 0.0 0.26 10.7 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein TPR_1 PF00515.28 CBK22153.2 - 0.59 10.1 3.2 0.24 11.3 0.3 1.9 2 0 0 2 2 1 0 Tetratricopeptide repeat ABC_tran PF00005.27 CBK22154.2 - 9e-74 246.5 0.0 1.3e-37 129.4 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 CBK22154.2 - 3.4e-56 190.9 14.2 4.4e-27 95.4 15.1 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region AAA_16 PF13191.6 CBK22154.2 - 1.1e-11 45.4 0.0 0.00018 22.0 0.0 2.8 2 0 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 CBK22154.2 - 3.9e-11 43.4 2.0 0.00067 19.9 0.0 4.1 2 2 0 2 2 2 2 AAA domain AAA PF00004.29 CBK22154.2 - 3e-09 37.4 0.8 0.00023 21.6 0.0 4.2 2 2 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) SMC_N PF02463.19 CBK22154.2 - 8.3e-09 35.2 11.8 0.0012 18.4 0.6 4.6 4 1 0 4 4 3 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 CBK22154.2 - 1.5e-08 34.2 0.3 0.0037 17.0 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 CBK22154.2 - 4.9e-08 33.1 0.1 0.012 15.6 0.0 2.7 2 0 0 2 2 2 2 RsgA GTPase AAA_21 PF13304.6 CBK22154.2 - 9.7e-08 32.2 0.9 0.83 9.4 0.2 4.4 3 1 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system G-alpha PF00503.20 CBK22154.2 - 5.9e-07 29.0 0.4 0.019 14.2 0.0 2.8 3 0 0 3 3 3 2 G-protein alpha subunit ABC_ATPase PF09818.9 CBK22154.2 - 2.8e-06 26.4 0.7 0.067 12.0 0.0 3.0 3 0 0 3 3 3 2 Predicted ATPase of the ABC class AAA_5 PF07728.14 CBK22154.2 - 3e-06 27.3 0.6 0.66 10.0 0.0 4.4 4 0 0 4 4 4 1 AAA domain (dynein-related subfamily) AAA_25 PF13481.6 CBK22154.2 - 3.3e-06 26.8 0.1 0.75 9.3 0.0 4.0 4 0 0 4 4 4 1 AAA domain AAA_30 PF13604.6 CBK22154.2 - 4.3e-06 26.6 0.5 0.24 11.1 0.2 3.8 3 1 0 3 3 3 2 AAA domain AAA_23 PF13476.6 CBK22154.2 - 7.5e-06 26.6 13.5 0.031 14.8 0.0 3.4 3 0 0 3 3 3 2 AAA domain SbcCD_C PF13558.6 CBK22154.2 - 2.1e-05 24.7 4.8 0.071 13.4 0.9 3.9 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit TniB PF05621.11 CBK22154.2 - 4e-05 23.1 0.1 5.1 6.5 0.0 4.2 4 0 0 4 4 4 0 Bacterial TniB protein AAA_11 PF13086.6 CBK22154.2 - 0.00013 21.9 0.3 0.0032 17.3 0.3 2.6 2 1 0 2 2 2 1 AAA domain AAA_7 PF12775.7 CBK22154.2 - 0.00015 21.3 0.1 0.19 11.2 0.0 2.5 2 0 0 2 2 2 2 P-loop containing dynein motor region IstB_IS21 PF01695.17 CBK22154.2 - 0.00017 21.4 0.1 1.5 8.5 0.0 3.8 4 0 0 4 4 3 1 IstB-like ATP binding protein CDC45 PF02724.14 CBK22154.2 - 0.00019 19.9 1.5 0.00029 19.3 1.5 1.2 1 0 0 1 1 1 1 CDC45-like protein MMR_HSR1 PF01926.23 CBK22154.2 - 0.0002 21.4 0.1 0.58 10.3 0.0 3.1 2 0 0 2 2 2 1 50S ribosome-binding GTPase RNA_helicase PF00910.22 CBK22154.2 - 0.00022 21.6 0.2 1.2 9.5 0.0 3.6 4 0 0 4 4 3 1 RNA helicase Rad17 PF03215.15 CBK22154.2 - 0.00034 20.6 0.0 0.22 11.5 0.0 2.6 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_15 PF13175.6 CBK22154.2 - 0.00061 19.6 9.8 0.41 10.3 0.0 3.3 2 1 0 2 2 2 1 AAA ATPase domain AAA_24 PF13479.6 CBK22154.2 - 0.00074 19.3 0.2 1.2 8.8 0.1 3.1 2 2 0 2 2 2 1 AAA domain NB-ARC PF00931.22 CBK22154.2 - 0.00087 18.5 0.2 1.1 8.4 0.0 2.8 2 0 0 2 2 2 1 NB-ARC domain Tim54 PF11711.8 CBK22154.2 - 0.001 18.0 1.8 0.0017 17.2 1.8 1.3 1 0 0 1 1 1 1 Inner membrane protein import complex subunit Tim54 PRK PF00485.18 CBK22154.2 - 0.0015 18.3 0.3 0.5 10.1 0.1 2.6 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family AAA_33 PF13671.6 CBK22154.2 - 0.0015 18.7 0.2 1.7 8.8 0.0 2.8 2 1 0 2 2 2 1 AAA domain AAA_18 PF13238.6 CBK22154.2 - 0.0017 18.9 9.0 0.72 10.4 0.1 4.4 5 0 0 5 5 4 2 AAA domain DEAD PF00270.29 CBK22154.2 - 0.0019 18.0 0.7 0.24 11.2 0.1 3.3 2 2 0 2 2 2 1 DEAD/DEAH box helicase ATP_bind_1 PF03029.17 CBK22154.2 - 0.0041 16.9 0.4 0.32 10.7 0.0 2.7 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein DUF87 PF01935.17 CBK22154.2 - 0.0064 16.6 5.1 0.25 11.4 0.0 3.8 3 0 0 3 3 3 1 Helicase HerA, central domain Zeta_toxin PF06414.12 CBK22154.2 - 0.0071 15.6 0.0 2.5 7.3 0.0 2.5 2 0 0 2 2 2 1 Zeta toxin Sigma54_activat PF00158.26 CBK22154.2 - 0.0079 15.9 0.0 4.5 6.9 0.0 3.2 3 0 0 3 3 3 0 Sigma-54 interaction domain Roc PF08477.13 CBK22154.2 - 0.0079 16.4 0.0 4 7.7 0.0 3.5 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase Raftlin PF15250.6 CBK22154.2 - 0.011 14.6 6.2 0.019 13.7 6.2 1.3 1 0 0 1 1 1 0 Raftlin MeaB PF03308.16 CBK22154.2 - 0.016 14.2 0.0 0.69 8.8 0.0 2.4 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB KAP_NTPase PF07693.14 CBK22154.2 - 0.02 14.2 0.1 0.33 10.1 0.1 2.4 2 0 0 2 2 2 0 KAP family P-loop domain AAA_14 PF13173.6 CBK22154.2 - 0.02 14.9 0.0 8 6.5 0.0 3.1 3 0 0 3 3 2 0 AAA domain Mg_chelatase PF01078.21 CBK22154.2 - 0.021 14.2 0.0 1.7 8.0 0.0 2.5 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI APS_kinase PF01583.20 CBK22154.2 - 0.022 14.7 0.1 2 8.3 0.0 2.6 2 0 0 2 2 2 0 Adenylylsulphate kinase NACHT PF05729.12 CBK22154.2 - 0.031 14.2 0.1 2.2 8.2 0.1 2.6 2 0 0 2 2 2 0 NACHT domain NTPase_1 PF03266.15 CBK22154.2 - 0.04 13.8 0.1 12 5.7 0.0 3.0 3 0 0 3 3 2 0 NTPase DUF4337 PF14235.6 CBK22154.2 - 0.048 13.8 2.7 0.18 11.9 2.7 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) ATP-synt_ab PF00006.25 CBK22154.2 - 0.078 12.6 0.0 4.4 6.9 0.0 2.3 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_28 PF13521.6 CBK22154.2 - 0.083 13.1 0.7 4 7.7 0.0 2.8 2 0 0 2 2 2 0 AAA domain Dynamin_N PF00350.23 CBK22154.2 - 0.088 12.9 3.2 15 5.6 0.0 3.5 3 0 0 3 3 3 0 Dynamin family AAA_19 PF13245.6 CBK22154.2 - 0.11 12.8 2.4 14 6.0 0.0 3.9 3 2 0 3 3 3 0 AAA domain DUF913 PF06025.12 CBK22154.2 - 0.15 11.0 2.6 0.77 8.7 1.1 2.4 3 0 0 3 3 2 0 Domain of Unknown Function (DUF913) Connexin PF00029.19 CBK22154.2 - 0.25 11.1 8.0 0.31 10.8 5.4 2.4 3 1 0 3 3 2 0 Connexin DUF262 PF03235.14 CBK22154.2 - 0.49 10.5 2.7 0.51 10.5 1.1 1.8 2 0 0 2 2 1 0 Protein of unknown function DUF262 Sec62 PF03839.16 CBK22154.2 - 0.5 9.8 4.4 1 8.8 4.4 1.5 1 0 0 1 1 1 0 Translocation protein Sec62 DUF2207 PF09972.9 CBK22154.2 - 1 8.1 9.3 0.023 13.5 0.4 2.4 2 1 0 2 2 2 0 Predicted membrane protein (DUF2207) DUF4604 PF15377.6 CBK22154.2 - 1.3 9.5 18.6 2.9 8.3 18.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4604) RR_TM4-6 PF06459.12 CBK22154.2 - 1.4 8.7 12.7 2.4 7.9 12.7 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Vfa1 PF08432.10 CBK22154.2 - 1.9 8.8 18.0 2 8.7 14.6 2.2 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 YqfQ PF14181.6 CBK22154.2 - 2.7 8.1 16.4 6.1 7.0 16.4 1.5 1 0 0 1 1 1 0 YqfQ-like protein RNA_pol_Rpc4 PF05132.14 CBK22154.2 - 2.9 8.3 8.5 5.8 7.3 8.5 1.4 1 0 0 1 1 1 0 RNA polymerase III RPC4 Coilin_N PF15862.5 CBK22154.2 - 4.3 7.2 13.2 2.8 7.7 10.8 1.9 2 0 0 2 2 1 0 Coilin N-terminus NPR3 PF03666.13 CBK22154.2 - 6.4 5.5 7.2 11 4.7 7.2 1.3 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 KH_1 PF00013.29 CBK22155.2 - 8.8e-46 153.6 15.0 1.1e-07 31.5 0.0 10.2 10 0 0 10 10 10 10 KH domain SLS PF14611.6 CBK22155.2 - 4.8e-14 52.7 13.1 0.056 13.3 0.2 7.4 1 1 4 7 7 7 4 Mitochondrial inner-membrane-bound regulator KH_2 PF07650.17 CBK22155.2 - 7e-10 38.6 16.8 0.046 13.5 0.1 6.4 6 1 0 6 6 6 3 KH domain Acyl_transf_1 PF00698.21 CBK22155.2 - 0.00016 21.3 9.0 0.0078 15.7 1.8 2.7 2 0 0 2 2 2 2 Acyl transferase domain KH_4 PF13083.6 CBK22155.2 - 0.0011 18.8 4.1 0.11 12.3 0.0 4.7 5 1 0 5 5 5 1 KH domain KH_5 PF13184.6 CBK22155.2 - 0.0013 18.8 8.2 0.65 10.1 0.2 5.2 6 0 0 6 6 6 1 NusA-like KH domain Secretin_N PF03958.17 CBK22155.2 - 0.0017 18.7 4.8 14 6.1 0.1 5.6 5 1 1 6 6 6 1 Bacterial type II/III secretion system short domain TubC_N PF18563.1 CBK22155.2 - 0.042 13.8 0.1 10 6.2 0.0 3.5 2 1 1 3 3 3 0 TubC N-terminal docking domain TPR_6 PF13174.6 CBK22155.2 - 0.084 13.6 0.5 1.1e+02 3.7 0.0 4.1 3 0 0 3 3 3 0 Tetratricopeptide repeat DNA_pol3_beta_3 PF02768.15 CBK22155.2 - 2.1 8.2 8.6 9.2 6.1 0.4 3.7 3 1 0 3 3 3 0 DNA polymerase III beta subunit, C-terminal domain KH_1 PF00013.29 CBK22156.2 - 7.2e-15 54.6 0.4 3.1e-10 39.7 0.2 2.6 2 0 0 2 2 2 2 KH domain KH_2 PF07650.17 CBK22156.2 - 0.00021 21.1 1.6 0.00087 19.1 1.3 2.4 1 1 1 2 2 2 1 KH domain SLS PF14611.6 CBK22156.2 - 0.0059 16.5 2.7 0.027 14.3 1.2 2.4 1 1 0 1 1 1 1 Mitochondrial inner-membrane-bound regulator MIS13 PF08202.11 CBK22156.2 - 0.0072 15.6 6.6 0.012 14.9 6.6 1.4 1 0 0 1 1 1 1 Mis12-Mtw1 protein family KH_5 PF13184.6 CBK22156.2 - 0.012 15.6 3.2 0.047 13.8 0.2 2.8 2 1 1 3 3 3 0 NusA-like KH domain SpoIISA_toxin PF14171.6 CBK22156.2 - 0.023 14.4 1.8 0.039 13.6 1.2 1.6 1 1 1 2 2 2 0 Toxin SpoIISA, type II toxin-antitoxin system HSBP1 PF06825.12 CBK22156.2 - 0.55 10.1 3.1 3.1 7.7 0.1 3.1 3 0 0 3 3 3 0 Heat shock factor binding protein 1 ABC_tran_CTD PF16326.5 CBK22156.2 - 3.2 8.1 10.1 1.6 9.0 1.2 3.4 3 1 0 3 3 3 0 ABC transporter C-terminal domain SOGA PF11365.8 CBK22156.2 - 3.5 8.8 14.6 9.3 7.5 4.3 3.0 1 1 1 2 2 2 0 Protein SOGA Telomerase_RBD PF12009.8 CBK22158.2 - 1.8e-14 54.0 0.4 4.3e-14 52.8 0.4 1.6 1 0 0 1 1 1 1 Telomerase ribonucleoprotein complex - RNA binding domain HCV_NS5a_1b PF08301.13 CBK22158.2 - 0.098 13.2 0.0 0.2 12.2 0.0 1.5 1 0 0 1 1 1 0 Hepatitis C virus non-structural 5a domain 1b Pkinase PF00069.25 CBK22159.2 - 3.6e-52 177.4 0.0 4.5e-52 177.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBK22159.2 - 9.2e-24 84.1 0.0 1.4e-23 83.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 CBK22159.2 - 0.0014 17.7 0.0 0.0017 17.4 0.0 1.1 1 0 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 CBK22159.2 - 0.018 13.8 0.1 0.024 13.4 0.1 1.1 1 0 0 1 1 1 0 Fungal protein kinase APH PF01636.23 CBK22159.2 - 0.07 13.0 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kinase-like PF14531.6 CBK22159.2 - 0.21 10.9 0.0 0.79 9.0 0.0 1.8 1 1 0 1 1 1 0 Kinase-like Phos_pyr_kin PF08543.12 CBK22160.2 - 2.4e-84 282.6 0.0 3.2e-84 282.2 0.0 1.1 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase TENA_THI-4 PF03070.16 CBK22160.2 - 2.1e-14 53.9 0.2 4e-14 52.9 0.2 1.4 1 0 0 1 1 1 1 TENA/THI-4/PQQC family PfkB PF00294.24 CBK22160.2 - 4.3e-05 23.0 0.0 8.9e-05 21.9 0.0 1.4 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Ribosomal_L19e PF01280.20 CBK22161.2 - 2.1e-57 193.2 11.9 2.7e-57 192.9 11.9 1.1 1 0 0 1 1 1 1 Ribosomal protein L19e AcetylCoA_hyd_C PF13336.6 CBK22162.2 - 3e-43 147.4 0.0 4.6e-43 146.8 0.0 1.3 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain AcetylCoA_hydro PF02550.15 CBK22162.2 - 1e-36 126.8 0.0 2.8e-36 125.4 0.0 1.7 2 0 0 2 2 2 1 Acetyl-CoA hydrolase/transferase N-terminal domain CoA_trans PF01144.23 CBK22162.2 - 0.082 12.3 0.1 0.27 10.6 0.0 1.9 2 0 0 2 2 2 0 Coenzyme A transferase DNA_primase_lrg PF04104.14 CBK22163.2 - 2.5e-30 105.8 0.0 2.9e-30 105.6 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase, large subunit CRM1_C PF08767.11 CBK22164.2 - 3.7e-54 184.1 4.4 5.3e-53 180.3 0.7 2.7 2 0 0 2 2 2 2 CRM1 C terminal Xpo1 PF08389.12 CBK22164.2 - 2.2e-20 73.2 4.3 9.7e-20 71.1 4.3 2.2 1 0 0 1 1 1 1 Exportin 1-like protein CRM1_repeat_2 PF18784.1 CBK22164.2 - 5.2e-20 70.9 2.6 2.8e-19 68.5 2.6 2.4 1 0 0 1 1 1 1 CRM1 / Exportin repeat 2 CRM1_repeat_3 PF18787.1 CBK22164.2 - 4.8e-14 52.2 0.0 1.7e-13 50.5 0.0 2.0 1 0 0 1 1 1 1 CRM1 / Exportin repeat 3 CRM1_repeat PF18777.1 CBK22164.2 - 9.9e-05 21.8 0.2 0.00035 20.0 0.2 2.0 1 0 0 1 1 1 1 Chromosome region maintenance or exportin repeat IBN_N PF03810.19 CBK22164.2 - 0.98 9.4 3.4 1.8 8.6 0.0 3.4 4 0 0 4 4 4 0 Importin-beta N-terminal domain VHS PF00790.19 CBK22165.2 - 4.7e-21 75.1 0.0 9.7e-21 74.1 0.0 1.6 1 0 0 1 1 1 1 VHS domain BChl_A PF02327.17 CBK22165.2 - 0.14 10.9 0.0 0.2 10.4 0.0 1.1 1 0 0 1 1 1 0 Bacteriochlorophyll A protein TAFH PF07531.14 CBK22165.2 - 0.17 12.0 1.1 0.42 10.7 0.0 2.2 3 0 0 3 3 3 0 NHR1 homology to TAF uDENN PF03456.18 CBK22166.2 - 6e-11 42.9 0.2 8.8e-11 42.4 0.2 1.3 1 0 0 1 1 1 1 uDENN domain DENN PF02141.21 CBK22167.2 - 4.6e-37 127.8 1.0 5.2e-37 127.6 1.0 1.0 1 0 0 1 1 1 1 DENN (AEX-3) domain SPA PF08616.10 CBK22167.2 - 9.5e-05 22.3 0.0 0.00015 21.7 0.0 1.3 1 0 0 1 1 1 1 Stabilization of polarity axis Avl9 PF09794.9 CBK22167.2 - 0.00048 18.9 0.1 0.0019 17.0 0.0 1.7 1 1 1 2 2 2 1 Transport protein Avl9 NAD_binding_5 PF07994.12 CBK22168.2 - 9.5e-143 475.4 0.0 1.1e-142 475.2 0.0 1.0 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase Inos-1-P_synth PF01658.17 CBK22168.2 - 5.4e-45 152.1 0.5 1.1e-44 151.1 0.1 1.8 2 0 0 2 2 2 1 Myo-inositol-1-phosphate synthase CBFD_NFYB_HMF PF00808.23 CBK22169.2 - 5.1e-12 45.9 0.1 7.2e-12 45.4 0.1 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Pox_polyA_pol_C PF12629.7 CBK22170.2 - 0.0096 15.8 0.1 0.016 15.0 0.1 1.3 1 0 0 1 1 1 1 Poxvirus poly(A) polymerase C-terminal domain ADD_ATRX PF17981.1 CBK22170.2 - 0.01 15.7 1.1 0.01 15.7 1.1 3.3 2 1 1 3 3 3 0 Cysteine Rich ADD domain zf-RING_5 PF14634.6 CBK22170.2 - 0.011 15.7 4.3 0.011 15.7 4.3 3.5 3 0 0 3 3 3 0 zinc-RING finger domain Lectin_N PF03954.14 CBK22170.2 - 0.51 10.1 2.8 0.32 10.7 0.8 1.6 2 0 0 2 2 2 0 Hepatic lectin, N-terminal domain zf-C3HC4_3 PF13920.6 CBK22170.2 - 1.3 8.9 22.9 0.59 10.0 13.0 3.4 2 2 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CBK22170.2 - 6.5 6.9 16.7 4.7 7.3 9.7 3.4 3 1 0 3 3 3 0 RING-type zinc-finger Pkinase PF00069.25 CBK22171.2 - 2e-43 148.7 0.0 2.3e-43 148.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBK22171.2 - 5.8e-33 114.3 0.0 7e-33 114.0 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase PI-PLC-X PF00388.19 CBK22172.2 - 0.00026 20.6 0.0 0.0013 18.4 0.0 1.8 1 1 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-C1 PF16670.5 CBK22172.2 - 0.11 11.5 0.4 0.58 9.2 0.0 1.9 2 0 0 2 2 2 0 Phosphoinositide phospholipase C, Ca2+-dependent Chlamy_scaf PF09675.10 CBK22172.2 - 0.19 12.1 0.0 0.28 11.6 0.0 1.3 1 0 0 1 1 1 0 Chlamydia-phage Chp2 scaffold (Chlamy_scaf) RNA_helicase PF00910.22 CBK22173.2 - 1.3e-08 35.1 0.0 3.3e-08 33.9 0.0 1.8 1 1 0 1 1 1 1 RNA helicase DNA_pol_B_2 PF03175.13 CBK22174.2 - 5e-17 61.9 14.5 1.8e-14 53.5 8.2 2.3 2 0 0 2 2 2 2 DNA polymerase type B, organellar and viral UTRA PF07702.13 CBK22174.2 - 0.15 11.9 0.0 0.28 11.0 0.0 1.4 1 0 0 1 1 1 0 UTRA domain Glyco_transf_49 PF13896.6 CBK22181.2 - 3e-21 76.1 6.4 6.7e-17 61.8 3.1 2.4 1 1 1 2 2 2 2 Glycosyl-transferase for dystroglycan PyrI_C PF02748.15 CBK22181.2 - 0.26 11.2 4.0 0.26 11.2 1.1 2.2 2 0 0 2 2 2 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain Bacteriocin_IIi PF11758.8 CBK22184.2 - 0.051 13.4 0.1 0.14 12.0 0.1 1.8 1 0 0 1 1 1 0 Aureocin-like type II bacteriocin Anth_Ig PF05587.13 CBK22184.2 - 0.18 12.1 0.9 0.34 11.2 0.2 1.7 2 0 0 2 2 2 0 Anthrax receptor extracellular domain TRAPP PF04051.16 CBK22185.2 - 6.8e-30 103.7 0.1 1.1e-29 103.1 0.1 1.3 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component Rad60-SLD PF11976.8 CBK22185.2 - 1.2e-13 50.7 0.2 6.6e-13 48.3 0.0 2.0 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 CBK22185.2 - 7.1e-06 25.7 0.0 1.2e-05 25.0 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family SH3_1 PF00018.28 CBK22186.2 - 1.8e-17 62.7 3.1 8.7e-12 44.5 0.2 3.1 3 0 0 3 3 3 2 SH3 domain SH3_9 PF14604.6 CBK22186.2 - 1.3e-16 60.2 2.1 2.2e-11 43.4 0.1 2.4 2 0 0 2 2 2 2 Variant SH3 domain SH3_2 PF07653.17 CBK22186.2 - 5.9e-12 45.1 0.3 1.7e-06 27.6 0.0 2.6 3 0 0 3 3 3 2 Variant SH3 domain SH3_3 PF08239.11 CBK22186.2 - 0.00031 21.0 1.4 0.22 11.8 0.2 2.4 2 0 0 2 2 2 2 Bacterial SH3 domain SH3_4 PF06347.13 CBK22186.2 - 0.00075 19.3 2.3 0.59 10.0 0.1 2.6 3 0 0 3 3 3 2 Bacterial SH3 domain Methyltransf_23 PF13489.6 CBK22187.2 - 4e-14 52.8 0.0 5.6e-14 52.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CBK22187.2 - 6.2e-14 52.4 0.0 1.7e-13 51.0 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CBK22187.2 - 2.4e-10 40.4 0.4 7e-08 32.4 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_25 PF13649.6 CBK22187.2 - 2.6e-10 40.9 0.1 3.1e-09 37.4 0.1 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CBK22187.2 - 3.6e-09 37.3 0.1 4.7e-08 33.7 0.1 2.2 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 CBK22187.2 - 1.9e-08 34.0 0.0 4.5e-08 32.7 0.0 1.9 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_8 PF05148.15 CBK22187.2 - 6.5e-07 29.4 0.0 1.8e-06 28.0 0.0 1.6 1 1 0 1 1 1 1 Hypothetical methyltransferase Methyltransf_29 PF03141.16 CBK22187.2 - 0.054 12.0 0.0 0.08 11.5 0.0 1.3 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase tRNA-synt_1d PF00750.19 CBK22190.2 - 3.3e-99 332.2 0.0 3.9e-99 331.9 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (R) DALR_1 PF05746.15 CBK22190.2 - 1.7e-30 105.7 0.0 7.3e-30 103.6 0.0 2.0 2 0 0 2 2 2 1 DALR anticodon binding domain tRNA-synt_1e PF01406.19 CBK22190.2 - 0.14 11.5 0.0 0.29 10.5 0.0 1.6 1 1 0 1 1 1 0 tRNA synthetases class I (C) catalytic domain FTCD_N PF07837.12 CBK22191.2 - 6.4e-71 237.8 0.0 9.6e-71 237.2 0.0 1.3 1 0 0 1 1 1 1 Formiminotransferase domain, N-terminal subdomain FTCD_C PF04961.12 CBK22191.2 - 1.1e-69 233.8 0.0 2.5e-69 232.7 0.0 1.6 1 0 0 1 1 1 1 Formiminotransferase-cyclodeaminase FTCD PF02971.14 CBK22191.2 - 3e-61 205.7 0.1 4.9e-61 205.0 0.1 1.4 1 0 0 1 1 1 1 Formiminotransferase domain Oxysterol_BP PF01237.18 CBK22192.2 - 4.6e-69 233.0 0.0 4.6e-67 226.5 0.0 2.0 1 1 0 1 1 1 1 Oxysterol-binding protein THUMP PF02926.17 CBK22193.2 - 4.7e-07 30.0 0.1 8e-07 29.3 0.1 1.3 1 0 0 1 1 1 1 THUMP domain GCV_H PF01597.19 CBK22195.2 - 9.8e-06 25.5 0.0 1.2e-05 25.2 0.0 1.2 1 0 0 1 1 1 1 Glycine cleavage H-protein Smr PF01713.21 CBK22195.2 - 0.11 12.9 0.0 0.18 12.2 0.0 1.5 1 0 0 1 1 1 0 Smr domain SET PF00856.28 CBK22196.2 - 4e-11 43.6 1.2 5.1e-10 40.0 0.0 2.4 2 0 0 2 2 2 1 SET domain CytochromB561_N PF09786.9 CBK22196.2 - 0.17 10.9 16.8 0.24 10.4 16.8 1.1 1 0 0 1 1 1 0 Cytochrome B561, N terminal Apt1 PF10351.9 CBK22196.2 - 1.3 7.8 14.0 1.7 7.4 14.0 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Macoilin PF09726.9 CBK22196.2 - 1.5 7.2 15.4 2.1 6.8 15.4 1.1 1 0 0 1 1 1 0 Macoilin family Hamartin PF04388.12 CBK22196.2 - 7.8 5.0 11.2 11 4.6 11.2 1.1 1 0 0 1 1 1 0 Hamartin protein fn3 PF00041.21 CBK22197.2 - 1e-05 25.8 0.3 2 8.8 0.0 5.3 5 0 0 5 5 5 1 Fibronectin type III domain EGF_2 PF07974.13 CBK22197.2 - 0.00088 19.6 40.8 0.00095 19.5 5.4 3.7 3 0 0 3 3 2 2 EGF-like domain hEGF PF12661.7 CBK22197.2 - 0.0023 18.5 17.8 0.046 14.4 3.9 3.3 2 0 0 2 2 2 2 Human growth factor-like EGF EGF PF00008.27 CBK22197.2 - 0.0027 18.0 16.3 0.25 11.7 2.5 2.9 2 0 0 2 2 2 2 EGF-like domain UPF0242 PF06785.11 CBK22197.2 - 0.014 15.5 2.1 0.025 14.7 2.1 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Peptidase_S49_N PF08496.10 CBK22197.2 - 0.025 14.6 2.0 0.9 9.6 1.5 2.2 2 0 0 2 2 2 0 Peptidase family S49 N-terminal DUF4446 PF14584.6 CBK22197.2 - 0.029 14.4 2.2 0.054 13.5 2.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) EphA2_TM PF14575.6 CBK22197.2 - 0.12 13.2 1.0 0.3 12.0 1.0 1.7 1 1 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Atthog PF18800.1 CBK22197.2 - 0.13 12.2 0.9 0.28 11.1 0.9 1.5 1 0 0 1 1 1 0 Attenuator of Hedgehog DUF1682 PF07946.14 CBK22197.2 - 0.4 9.8 7.9 0.68 9.1 7.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) DUF4355 PF14265.6 CBK22197.2 - 4.5 7.5 12.3 8.5 6.6 12.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4355) TPR_2 PF07719.17 CBK22198.2 - 3.6e-11 42.3 0.0 0.00026 20.9 0.0 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.28 CBK22198.2 - 1.6e-10 40.3 0.0 3.4e-05 23.5 0.0 2.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 CBK22198.2 - 6e-09 35.4 0.0 0.0085 16.2 0.0 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.6 CBK22198.2 - 1.1e-06 28.8 0.1 0.06 13.6 0.0 3.0 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 CBK22198.2 - 1.2e-05 25.0 0.0 0.0013 18.6 0.0 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat RPN7 PF10602.9 CBK22198.2 - 0.0014 18.4 0.1 0.0025 17.6 0.1 1.4 1 0 0 1 1 1 1 26S proteasome subunit RPN7 TPR_6 PF13174.6 CBK22198.2 - 0.0014 19.1 0.1 2 9.3 0.0 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat ANAPC3 PF12895.7 CBK22198.2 - 0.0026 18.0 0.0 0.0061 16.8 0.0 1.8 1 1 1 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.6 CBK22198.2 - 0.024 15.0 0.0 6.5 7.4 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat SNAP PF14938.6 CBK22198.2 - 0.025 14.0 0.0 0.043 13.2 0.0 1.3 1 0 0 1 1 1 0 Soluble NSF attachment protein, SNAP TPR_19 PF14559.6 CBK22198.2 - 0.025 15.1 0.0 0.08 13.5 0.0 2.0 1 1 1 2 2 2 0 Tetratricopeptide repeat Sec2p PF06428.11 CBK22198.2 - 0.054 13.5 0.6 0.12 12.3 0.6 1.6 1 1 0 1 1 1 0 GDP/GTP exchange factor Sec2p TPR_14 PF13428.6 CBK22198.2 - 0.068 14.0 0.0 11 7.2 0.0 3.1 2 1 0 2 2 2 0 Tetratricopeptide repeat TSP_NTD PF17804.1 CBK22198.2 - 0.076 13.3 0.0 0.11 12.7 0.0 1.2 1 0 0 1 1 1 0 Tail specific protease N-terminal domain Ribonuclease_T2 PF00445.18 CBK22198.2 - 0.093 13.0 0.1 0.12 12.6 0.1 1.2 1 0 0 1 1 1 0 Ribonuclease T2 family Coatomer_E PF04733.14 CBK22198.2 - 0.11 11.9 0.0 0.17 11.2 0.0 1.3 1 1 0 1 1 1 0 Coatomer epsilon subunit DUF3746 PF12562.8 CBK22198.2 - 0.14 12.1 0.4 0.63 10.0 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3746) PknG_TPR PF16918.5 CBK22198.2 - 0.16 10.7 0.0 0.23 10.1 0.0 1.2 1 0 0 1 1 1 0 Protein kinase G tetratricopeptide repeat TruD PF01142.18 CBK22200.2 - 5.8e-76 256.0 0.0 6e-69 232.9 0.0 2.2 2 0 0 2 2 2 2 tRNA pseudouridine synthase D (TruD) MRP-L47 PF06984.13 CBK22200.2 - 4.1e-27 94.1 0.4 4.1e-27 94.1 0.4 2.6 2 0 0 2 2 2 1 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) UDG PF03167.19 CBK22200.2 - 1.4e-20 73.9 0.0 2.7e-20 72.9 0.0 1.5 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily Ribosomal_L29 PF00831.23 CBK22200.2 - 0.045 13.7 0.1 0.11 12.4 0.1 1.8 1 0 0 1 1 1 0 Ribosomal L29 protein Methyltransf_10 PF05971.12 CBK22201.2 - 1.3e-56 192.2 0.1 2.2e-55 188.1 0.1 2.0 1 1 0 1 1 1 1 RNA methyltransferase PrmA PF06325.13 CBK22201.2 - 7.3e-05 22.3 0.0 0.00013 21.4 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 CBK22201.2 - 0.00011 21.8 0.0 0.00018 21.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.12 CBK22201.2 - 0.011 16.5 0.0 0.16 12.7 0.0 2.3 1 1 0 1 1 1 0 Methyltransferase domain Cauli_VI PF01693.16 CBK22201.2 - 0.061 13.6 0.9 0.24 11.8 0.4 2.0 2 0 0 2 2 2 0 Caulimovirus viroplasmin SCP2 PF02036.17 CBK22202.2 - 0.077 13.5 0.0 0.15 12.6 0.0 1.4 1 0 0 1 1 1 0 SCP-2 sterol transfer family AAA PF00004.29 CBK22203.2 - 9.6e-34 116.7 0.0 1.4e-33 116.1 0.0 1.2 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.14 CBK22203.2 - 3.2e-05 24.1 0.0 6.7e-05 23.1 0.0 1.5 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 CBK22203.2 - 0.00012 22.5 0.4 0.014 15.8 0.1 2.4 1 1 1 2 2 2 1 AAA ATPase domain AAA_5 PF07728.14 CBK22203.2 - 0.0017 18.4 0.3 0.016 15.2 0.3 2.4 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 CBK22203.2 - 0.0064 17.0 0.0 0.01 16.4 0.0 1.4 1 1 0 1 1 1 1 AAA domain ATPase_2 PF01637.18 CBK22203.2 - 0.013 15.5 0.0 0.069 13.0 0.0 2.0 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea AAA_22 PF13401.6 CBK22203.2 - 0.017 15.4 1.7 0.94 9.7 0.1 2.5 1 1 1 2 2 2 0 AAA domain TIP49 PF06068.13 CBK22203.2 - 0.033 13.4 0.0 0.043 13.0 0.0 1.2 1 0 0 1 1 1 0 TIP49 P-loop domain RNA_helicase PF00910.22 CBK22203.2 - 0.033 14.6 0.1 0.43 11.0 0.1 2.6 2 1 0 2 2 2 0 RNA helicase Mg_chelatase PF01078.21 CBK22203.2 - 0.078 12.4 0.0 0.15 11.4 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI RuvB_N PF05496.12 CBK22203.2 - 0.095 12.4 0.1 0.22 11.3 0.1 1.7 1 1 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_25 PF13481.6 CBK22203.2 - 0.12 12.0 0.3 3.2 7.3 0.1 2.3 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 CBK22203.2 - 0.2 11.3 0.0 0.37 10.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain GAS PF13851.6 CBK22204.2 - 0.00069 19.0 16.6 0.00084 18.7 16.6 1.2 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding Med21 PF11221.8 CBK22204.2 - 0.0013 19.0 1.4 0.0013 19.0 1.4 2.2 2 0 0 2 2 2 1 Subunit 21 of Mediator complex Atg14 PF10186.9 CBK22204.2 - 0.0047 16.1 12.4 0.0061 15.7 12.4 1.1 1 0 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 APG6_N PF17675.1 CBK22204.2 - 0.0095 16.5 22.7 0.041 14.4 8.4 2.2 1 1 1 2 2 2 1 Apg6 coiled-coil region DUF2570 PF10828.8 CBK22204.2 - 0.021 14.7 11.6 0.021 14.7 11.6 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2570) HemN_C PF06969.16 CBK22204.2 - 0.033 14.3 1.6 0.075 13.1 0.2 2.3 2 1 0 2 2 2 0 HemN C-terminal domain Syntaxin_2 PF14523.6 CBK22204.2 - 0.035 14.5 13.4 1.1 9.6 0.7 2.3 1 1 1 2 2 2 0 Syntaxin-like protein Med9 PF07544.13 CBK22204.2 - 0.066 13.3 14.0 0.79 9.9 0.3 3.4 1 1 2 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 WDCP PF15390.6 CBK22204.2 - 0.076 11.4 7.1 0.088 11.2 7.1 1.0 1 0 0 1 1 1 0 WD repeat and coiled-coil-containing protein family Prominin PF05478.11 CBK22204.2 - 0.13 10.2 10.1 0.14 10.1 10.1 1.0 1 0 0 1 1 1 0 Prominin DUF1664 PF07889.12 CBK22204.2 - 0.17 11.9 11.4 0.41 10.7 10.4 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) YABBY PF04690.13 CBK22204.2 - 0.18 12.4 5.8 0.24 12.0 5.8 1.3 1 0 0 1 1 1 0 YABBY protein ABC_tran_CTD PF16326.5 CBK22204.2 - 0.21 11.9 22.1 0.52 10.6 7.2 2.9 1 1 2 3 3 3 0 ABC transporter C-terminal domain DUF4446 PF14584.6 CBK22204.2 - 0.24 11.4 13.2 0.036 14.0 7.5 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF4446) ATG16 PF08614.11 CBK22204.2 - 0.26 11.5 17.4 0.38 11.0 9.1 2.2 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) BPS1 PF05633.11 CBK22204.2 - 0.4 9.7 6.6 0.47 9.4 6.6 1.2 1 0 0 1 1 1 0 Protein BYPASS1-related Exonuc_VII_L PF02601.15 CBK22204.2 - 0.68 9.4 7.4 0.79 9.2 7.4 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit LMBR1 PF04791.16 CBK22204.2 - 0.72 8.7 5.8 0.87 8.4 5.8 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein FapA PF03961.13 CBK22204.2 - 0.73 8.4 12.7 0.87 8.1 12.7 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A PHM7_cyt PF14703.6 CBK22204.2 - 0.75 10.0 11.2 1.3 9.2 10.9 1.5 1 1 0 1 1 1 0 Cytosolic domain of 10TM putative phosphate transporter Nop PF01798.18 CBK22204.2 - 0.89 9.0 9.3 1.1 8.7 9.3 1.1 1 0 0 1 1 1 0 snoRNA binding domain, fibrillarin zf-C4H2 PF10146.9 CBK22204.2 - 0.94 9.7 19.0 1.1 9.5 18.1 1.5 1 1 1 2 2 2 0 Zinc finger-containing protein Fzo_mitofusin PF04799.13 CBK22204.2 - 1 8.9 12.5 0.31 10.6 2.3 2.2 1 1 1 2 2 2 0 fzo-like conserved region Fib_alpha PF08702.10 CBK22204.2 - 1.3 9.2 15.8 4.4 7.5 15.6 1.5 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family Spc7 PF08317.11 CBK22204.2 - 1.8 7.3 20.8 4 6.2 20.8 1.6 1 1 0 1 1 1 0 Spc7 kinetochore protein Snapin_Pallidin PF14712.6 CBK22204.2 - 2.1 8.8 15.9 1.2 9.6 4.2 2.5 1 1 1 2 2 2 0 Snapin/Pallidin DUF4407 PF14362.6 CBK22204.2 - 2.2 7.6 7.9 2.5 7.4 7.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Mod_r PF07200.13 CBK22204.2 - 2.5 8.2 21.1 0.83 9.8 11.0 2.2 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein TMPIT PF07851.13 CBK22204.2 - 2.8 7.1 10.6 3.9 6.6 10.6 1.2 1 0 0 1 1 1 0 TMPIT-like protein Cep57_CLD_2 PF14197.6 CBK22204.2 - 2.9 8.0 14.5 1.1 9.5 2.0 2.6 1 1 1 2 2 2 0 Centrosome localisation domain of PPC89 DivIC PF04977.15 CBK22204.2 - 5.3 6.9 21.0 3.1 7.6 6.5 2.5 1 1 1 2 2 2 0 Septum formation initiator EMP24_GP25L PF01105.24 CBK22204.2 - 5.6 6.9 13.8 14 5.5 13.7 1.6 1 1 0 1 1 1 0 emp24/gp25L/p24 family/GOLD YabA PF06156.13 CBK22204.2 - 6.4 7.5 16.1 27 5.5 8.5 2.3 1 1 1 2 2 2 0 Initiation control protein YabA PCRF PF03462.18 CBK22204.2 - 7.5 6.4 14.1 8 6.3 13.4 1.5 1 1 0 1 1 1 0 PCRF domain VIT1 PF01988.19 CBK22204.2 - 8.6 6.2 5.8 12 5.7 5.8 1.2 1 0 0 1 1 1 0 VIT family PseudoU_synth_1 PF01416.20 CBK22205.2 - 4.6e-27 94.6 0.0 3.3e-26 91.8 0.0 2.1 2 0 0 2 2 2 1 tRNA pseudouridine synthase DUF1673 PF07895.11 CBK22205.2 - 0.14 11.9 0.1 0.25 11.1 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1673) Ras PF00071.22 CBK22206.2 - 2.2e-57 193.2 0.0 2.9e-57 192.8 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CBK22206.2 - 2.8e-34 117.9 0.1 5.9e-34 116.9 0.1 1.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CBK22206.2 - 1.9e-13 50.2 0.1 2.8e-13 49.7 0.1 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 CBK22206.2 - 0.0002 20.8 0.1 0.0004 19.8 0.0 1.6 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 CBK22206.2 - 0.00034 20.7 0.0 0.00057 19.9 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 CBK22206.2 - 0.0013 18.6 0.1 2 8.3 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 CBK22206.2 - 0.0014 18.2 0.0 0.0026 17.3 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_16 PF13191.6 CBK22206.2 - 0.014 15.8 1.9 0.26 11.6 2.0 2.6 1 1 0 1 1 1 0 AAA ATPase domain TniB PF05621.11 CBK22206.2 - 0.063 12.7 0.0 0.15 11.4 0.0 1.6 1 0 0 1 1 1 0 Bacterial TniB protein MnmE_helical PF12631.7 CBK22206.2 - 0.16 12.1 0.1 15 5.7 0.0 2.1 2 0 0 2 2 2 0 MnmE helical domain FUSC PF04632.12 CBK22206.2 - 0.31 9.5 5.5 0.44 9.0 5.5 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family Vps54_N PF10475.9 CBK22207.2 - 4.8e-28 98.3 2.8 1.9e-27 96.3 2.3 1.9 2 0 0 2 2 2 1 Vacuolar-sorting protein 54, of GARP complex Sec8_exocyst PF04048.14 CBK22207.2 - 0.00029 20.7 3.8 0.00032 20.6 2.0 2.0 2 0 0 2 2 2 1 Sec8 exocyst complex component specific domain COG2 PF06148.11 CBK22207.2 - 0.31 11.1 4.1 0.81 9.8 1.7 2.5 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Peptidase_M1 PF01433.20 CBK22208.2 - 6.9e-75 251.3 0.1 1.1e-74 250.7 0.1 1.3 1 0 0 1 1 1 1 Peptidase family M1 domain Peptidase_M1_N PF17900.1 CBK22208.2 - 1.3e-28 100.5 0.1 1.9e-28 99.9 0.1 1.3 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain ERAP1_C PF11838.8 CBK22208.2 - 3.5e-24 85.9 0.0 7.1e-24 84.9 0.0 1.5 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Peptidase_M61 PF05299.12 CBK22208.2 - 0.038 14.4 0.3 0.086 13.2 0.3 1.6 1 0 0 1 1 1 0 M61 glycyl aminopeptidase ERAP1_C PF11838.8 CBK22209.2 - 0.072 12.6 0.0 0.084 12.4 0.0 1.1 1 0 0 1 1 1 0 ERAP1-like C-terminal domain RP-C PF03428.13 CBK22209.2 - 0.08 12.6 0.2 0.098 12.3 0.2 1.1 1 0 0 1 1 1 0 Replication protein C N-terminal domain IIGP PF05049.13 CBK22209.2 - 0.098 11.7 0.0 0.1 11.6 0.0 1.0 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) MORN_2 PF07661.13 CBK22210.2 - 1.4 9.4 5.8 1e+02 3.7 0.1 3.9 3 0 0 3 3 3 0 MORN repeat variant WD40 PF00400.32 CBK22212.2 - 2.8e-26 91.2 1.8 5e-10 39.8 0.0 4.3 4 0 0 4 4 4 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBK22212.2 - 3.4e-17 62.5 0.0 0.00029 21.1 0.0 4.1 1 1 3 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 CBK22212.2 - 6.4e-07 28.6 0.7 0.0033 16.4 0.3 3.6 1 1 2 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein IKI3 PF04762.12 CBK22212.2 - 0.00031 18.9 0.0 0.0008 17.5 0.0 1.6 1 1 1 2 2 2 1 IKI3 family Coatomer_WDAD PF04053.14 CBK22212.2 - 0.00062 18.9 0.0 0.022 13.9 0.0 2.1 1 1 1 2 2 2 1 Coatomer WD associated region eIF2A PF08662.11 CBK22212.2 - 0.00099 19.0 0.0 0.011 15.6 0.0 2.0 1 1 1 2 2 2 1 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 CBK22212.2 - 0.0018 17.0 0.8 0.12 11.0 0.1 2.7 2 1 1 3 3 3 1 Nucleoporin Nup120/160 PD40 PF07676.12 CBK22212.2 - 0.0039 17.1 0.5 0.96 9.5 0.2 3.0 2 0 0 2 2 2 1 WD40-like Beta Propeller Repeat NUC194 PF08163.12 CBK22212.2 - 0.17 10.8 0.3 0.27 10.1 0.3 1.3 1 0 0 1 1 1 0 NUC194 domain Glyco_transf_20 PF00982.21 CBK22214.2 - 1.4e-69 235.0 0.0 2e-69 234.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.16 CBK22214.2 - 2e-33 115.5 0.0 3.3e-33 114.8 0.0 1.3 1 0 0 1 1 1 1 Trehalose-phosphatase Acetyltransf_3 PF13302.7 CBK22215.2 - 6.7e-21 75.4 0.1 9.9e-21 74.9 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 CBK22215.2 - 2.1e-09 37.7 0.0 3e-09 37.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.10 CBK22215.2 - 1.4e-06 28.2 0.0 2.8e-06 27.2 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_4 PF13420.7 CBK22215.2 - 1.8e-06 28.1 1.2 2.4e-06 27.8 1.2 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 CBK22215.2 - 9.6e-05 22.7 0.1 0.00022 21.6 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 CBK22215.2 - 0.0024 17.6 0.0 0.0059 16.3 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain GNAT_acetyltran PF12746.7 CBK22215.2 - 0.051 13.1 0.0 0.075 12.6 0.0 1.3 1 0 0 1 1 1 0 GNAT acetyltransferase Big_5 PF13205.6 CBK22217.2 - 6.2e-07 30.1 0.1 1.1e-06 29.3 0.1 1.4 1 0 0 1 1 1 1 Bacterial Ig-like domain Sld5 PF05916.11 CBK22218.2 - 2e-14 54.0 3.4 3.4e-14 53.2 3.2 1.5 1 1 1 2 2 2 1 GINS complex protein HAP1_N PF04849.13 CBK22218.2 - 0.027 13.7 0.3 0.036 13.3 0.3 1.1 1 0 0 1 1 1 0 HAP1 N-terminal conserved region CSD PF00313.22 CBK22219.2 - 1.3e-11 44.1 0.0 1.9e-11 43.7 0.0 1.2 1 0 0 1 1 1 1 'Cold-shock' DNA-binding domain FapA PF03961.13 CBK22220.2 - 0.033 12.8 3.6 0.038 12.6 3.6 1.0 1 0 0 1 1 1 0 Flagellar Assembly Protein A BRE1 PF08647.11 CBK22220.2 - 0.081 13.0 5.8 0.15 12.1 3.2 2.0 1 1 1 2 2 2 0 BRE1 E3 ubiquitin ligase YabA PF06156.13 CBK22220.2 - 0.23 12.1 5.2 0.24 12.0 4.1 1.6 1 1 0 1 1 1 0 Initiation control protein YabA ZapB PF06005.12 CBK22221.2 - 0.00059 20.2 30.2 0.012 16.1 10.5 3.3 2 1 1 3 3 3 2 Cell division protein ZapB TMF_TATA_bd PF12325.8 CBK22221.2 - 0.0015 18.7 27.1 0.015 15.5 8.2 2.5 1 1 1 2 2 2 2 TATA element modulatory factor 1 TATA binding SHE3 PF17078.5 CBK22221.2 - 0.051 13.3 20.0 0.45 10.2 20.0 2.0 1 1 0 1 1 1 0 SWI5-dependent HO expression protein 3 UPF0242 PF06785.11 CBK22221.2 - 0.094 12.8 28.9 0.07 13.2 20.0 2.1 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus DUF4763 PF15960.5 CBK22221.2 - 0.17 11.2 25.6 0.45 9.8 10.7 2.1 1 1 0 2 2 2 0 Domain of unknown function (DUF4763) Laminin_II PF06009.12 CBK22221.2 - 0.28 11.2 19.2 0.047 13.7 5.4 2.1 1 1 1 2 2 2 0 Laminin Domain II DUF5082 PF16888.5 CBK22221.2 - 0.39 11.0 21.4 13 6.1 0.4 4.0 1 1 1 3 3 3 0 Domain of unknown function (DUF5082) GAS PF13851.6 CBK22221.2 - 0.52 9.6 27.9 1 8.7 8.4 2.5 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding KASH_CCD PF14662.6 CBK22221.2 - 0.56 10.0 27.4 2 8.2 6.9 3.0 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 or KASH bZIP_1 PF00170.21 CBK22221.2 - 0.58 10.3 23.6 1.7 8.8 0.7 4.2 3 1 1 4 4 4 0 bZIP transcription factor Jnk-SapK_ap_N PF09744.9 CBK22221.2 - 0.72 10.1 28.0 0.09 13.0 17.8 2.8 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 OrfB_IS605 PF01385.19 CBK22221.2 - 0.9 9.8 7.5 1.4 9.2 0.2 2.9 1 1 1 3 3 3 0 Probable transposase MCC-bdg_PDZ PF10506.9 CBK22221.2 - 1.2 9.2 22.5 0.21 11.6 0.9 4.5 3 1 0 3 3 3 0 PDZ domain of MCC-2 bdg protein for Usher syndrome DUF4407 PF14362.6 CBK22221.2 - 1.2 8.4 18.8 6.1 6.1 7.2 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) TPR_MLP1_2 PF07926.12 CBK22221.2 - 1.5 8.9 31.7 4.5 7.3 3.6 3.8 1 1 2 4 4 4 0 TPR/MLP1/MLP2-like protein Cortex-I_coil PF09304.10 CBK22221.2 - 2.8 8.2 20.8 6.3 7.1 4.7 3.1 1 1 1 2 2 2 0 Cortexillin I, coiled coil Tup_N PF08581.10 CBK22221.2 - 3.6 8.0 19.1 0.21 11.9 11.1 2.7 1 1 0 2 2 2 0 Tup N-terminal Spc7 PF08317.11 CBK22221.2 - 4.7 6.0 27.1 0.49 9.2 19.4 2.0 1 1 1 2 2 2 0 Spc7 kinetochore protein Fzo_mitofusin PF04799.13 CBK22221.2 - 6.2 6.4 17.9 0.88 9.1 3.9 2.5 1 1 1 2 2 2 0 fzo-like conserved region Csm1_N PF18504.1 CBK22221.2 - 6.6 7.2 25.6 1.3 9.5 1.2 4.1 1 1 1 3 3 3 0 Csm1 N-terminal domain Fungal_TACC PF12709.7 CBK22221.2 - 7.3 7.1 23.4 10 6.7 1.3 4.2 1 1 3 4 4 4 0 Fungal Transforming acidic coiled-coil (TACC) proteins NOT2_3_5 PF04153.18 CBK22222.2 - 3.6e-15 56.2 0.1 7e-15 55.3 0.1 1.5 1 0 0 1 1 1 1 NOT2 / NOT3 / NOT5 family NIF PF03031.18 CBK22223.2 - 1.1e-19 70.7 0.0 2.2e-19 69.8 0.0 1.5 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase BRCT_2 PF16589.5 CBK22223.2 - 3.8e-05 24.0 0.0 7.7e-05 23.0 0.0 1.6 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain PTCB-BRCT PF12738.7 CBK22223.2 - 0.00024 21.0 0.0 0.00076 19.4 0.0 1.8 1 0 0 1 1 1 1 twin BRCT domain BRCT PF00533.26 CBK22223.2 - 0.00067 20.0 0.0 0.0025 18.2 0.0 2.0 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain HAD_2 PF13419.6 CBK22223.2 - 0.016 15.3 5.7 0.2 11.7 0.1 3.2 2 1 1 3 3 3 0 Haloacid dehalogenase-like hydrolase RAMP PF04901.13 CBK22223.2 - 0.14 12.1 0.1 0.46 10.5 0.1 1.8 1 1 0 1 1 1 0 Receptor activity modifying family THF_DHG_CYH_C PF02882.19 CBK22224.2 - 1.3e-18 66.8 0.0 2.1e-18 66.2 0.0 1.2 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.23 CBK22224.2 - 4.3e-18 65.7 0.3 8.3e-18 64.8 0.3 1.5 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain DDRGK PF09756.9 CBK22224.2 - 0.062 12.9 0.0 0.096 12.3 0.0 1.2 1 0 0 1 1 1 0 DDRGK domain HMA PF00403.26 CBK22224.2 - 0.09 13.2 0.0 0.89 10.1 0.0 2.5 2 0 0 2 2 2 0 Heavy-metal-associated domain Ribosomal_L7Ae PF01248.26 CBK22225.2 - 3.5e-24 84.3 0.0 4.1e-24 84.1 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family EF_assoc_2 PF08356.12 CBK22226.2 - 7e-07 29.2 0.0 1.7e-06 27.9 0.0 1.6 1 0 0 1 1 1 1 EF hand associated EF_assoc_1 PF08355.12 CBK22226.2 - 7.1e-07 28.7 0.2 1.3e-06 27.9 0.2 1.4 1 0 0 1 1 1 1 EF hand associated Bac_chlorC PF02043.17 CBK22227.2 - 0.01 15.8 3.0 3.2 7.8 0.2 2.4 2 0 0 2 2 2 0 Bacteriochlorophyll C binding protein CsgA PF17334.2 CBK22227.2 - 0.014 16.2 1.0 8.2 7.2 0.1 2.4 2 0 0 2 2 2 0 Minor curli fiber component A DUF5105 PF17118.5 CBK22227.2 - 0.049 13.4 0.0 13 5.5 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF5105) SAM_PNT PF02198.16 CBK22227.2 - 0.087 12.8 0.0 22 5.1 0.0 2.4 2 0 0 2 2 2 0 Sterile alpha motif (SAM)/Pointed domain B3R PF17057.5 CBK22227.2 - 0.088 13.0 0.0 24 5.1 0.0 2.4 2 0 0 2 2 2 0 Poxviridae B3 protein SLATT_1 PF18181.1 CBK22228.2 - 0.12 12.3 0.1 0.21 11.5 0.1 1.3 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain 1 DUF1129 PF06570.11 CBK22228.2 - 0.14 11.6 0.1 0.31 10.5 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) Peptidase_M16 PF00675.20 CBK22229.2 - 1.3e-33 116.1 0.1 1.4e-33 116.0 0.1 1.0 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) SUFU PF05076.13 CBK22229.2 - 0.12 12.3 0.0 0.2 11.6 0.0 1.4 1 1 0 1 1 1 0 Suppressor of fused protein (SUFU) Peptidase_M16_M PF16187.5 CBK22230.2 - 5.6e-37 127.5 0.0 7.1e-37 127.2 0.0 1.1 1 0 0 1 1 1 1 Middle or third domain of peptidase_M16 Peptidase_M16_C PF05193.21 CBK22230.2 - 0.00055 20.0 0.1 0.00081 19.5 0.1 1.2 1 0 0 1 1 1 1 Peptidase M16 inactive domain DEAD PF00270.29 CBK22232.2 - 2e-37 128.6 0.1 4.6e-37 127.5 0.1 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CBK22232.2 - 3.1e-25 88.7 0.5 7.3e-25 87.5 0.2 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 CBK22232.2 - 1e-09 38.6 0.0 1.7e-09 37.9 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 CBK22232.2 - 5.1e-05 22.7 0.1 0.00017 21.0 0.0 1.9 2 0 0 2 2 2 1 U3-containing 90S pre-ribosomal complex subunit CDC37_C PF08564.10 CBK22232.2 - 0.0027 17.8 0.4 0.0072 16.4 0.0 1.9 2 0 0 2 2 2 1 Cdc37 C terminal domain AAA_19 PF13245.6 CBK22232.2 - 0.023 15.0 0.4 0.14 12.5 0.4 2.3 1 1 0 1 1 1 0 AAA domain GHL10 PF02638.15 CBK22232.2 - 0.06 12.4 0.1 0.11 11.5 0.1 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase-like 10 UDG PF03167.19 CBK22233.2 - 5.3e-06 26.5 0.0 3.9e-05 23.7 0.0 2.0 1 1 0 1 1 1 1 Uracil DNA glycosylase superfamily Clathrin_lg_ch PF01086.17 CBK22234.2 - 1.8e-19 70.8 7.3 2.1e-19 70.5 7.3 1.1 1 0 0 1 1 1 1 Clathrin light chain LRR_8 PF13855.6 CBK22235.2 - 5e-29 99.8 40.9 1.4e-14 53.5 6.5 5.6 2 1 3 5 5 5 5 Leucine rich repeat LRR_4 PF12799.7 CBK22235.2 - 9.6e-27 92.6 37.5 1e-09 38.5 1.1 6.3 3 2 4 7 7 7 6 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 CBK22235.2 - 3.8e-09 36.3 10.7 5.9e-05 22.6 2.3 3.1 1 1 2 3 3 3 3 Leucine-rich repeat LRR_1 PF00560.33 CBK22235.2 - 3.5e-08 32.9 29.9 0.82 10.4 0.2 8.5 7 2 1 8 8 8 4 Leucine Rich Repeat LRR_6 PF13516.6 CBK22235.2 - 2.3e-07 30.3 39.8 0.016 15.2 0.3 9.0 9 0 0 9 9 9 5 Leucine Rich repeat LRR_5 PF13306.6 CBK22235.2 - 8.6e-07 29.0 0.9 2.5e-06 27.5 0.6 1.9 1 1 0 1 1 1 1 BspA type Leucine rich repeat region (6 copies) DNA_pol_B_2 PF03175.13 CBK22237.2 - 5.2e-19 68.5 12.7 1.8e-18 66.7 12.7 1.9 1 1 0 1 1 1 1 DNA polymerase type B, organellar and viral DNA_pol_B_2 PF03175.13 CBK22238.2 - 1.2e-15 57.4 13.6 3.9e-13 49.1 9.5 2.3 2 0 0 2 2 2 2 DNA polymerase type B, organellar and viral DNA_pol_B_2 PF03175.13 CBK22239.2 - 1.7e-16 60.1 14.9 2.6e-13 49.7 10.2 2.3 2 0 0 2 2 2 2 DNA polymerase type B, organellar and viral AhpC-TSA PF00578.21 CBK22241.2 - 8e-36 122.7 0.0 1.1e-35 122.3 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 CBK22241.2 - 1.2e-11 44.6 0.0 1.5e-11 44.2 0.0 1.1 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.9 CBK22241.2 - 1.8e-11 43.7 0.0 3.8e-11 42.6 0.0 1.5 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin EMP24_GP25L PF01105.24 CBK22242.2 - 3.3e-28 98.9 3.3 3.7e-28 98.7 3.3 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD SNF2_N PF00176.23 CBK22243.2 - 4.3e-57 193.4 0.1 6.5e-57 192.8 0.1 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 CBK22243.2 - 3.2e-21 75.8 0.0 7.2e-20 71.4 0.0 3.2 5 0 0 5 5 5 1 Helicase conserved C-terminal domain ResIII PF04851.15 CBK22243.2 - 5.1e-07 29.9 0.0 1.3e-05 25.2 0.0 2.6 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.29 CBK22243.2 - 0.0029 17.4 0.0 0.0068 16.2 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF4407 PF14362.6 CBK22243.2 - 7.8 5.8 12.3 32 3.7 12.4 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) ACBP PF00887.19 CBK22244.2 - 1e-16 60.9 0.0 1.7e-16 60.2 0.0 1.4 1 0 0 1 1 1 1 Acyl CoA binding protein zf-FLZ PF04570.14 CBK22246.2 - 4e-09 35.8 4.8 4e-09 35.8 4.8 1.5 2 0 0 2 2 2 1 zinc-finger of the FCS-type, C2-C2 PyrI_C PF02748.15 CBK22246.2 - 0.017 15.0 0.3 0.017 15.0 0.3 1.5 2 0 0 2 2 2 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-FCS PF06467.14 CBK22246.2 - 0.048 13.6 3.0 0.39 10.7 0.5 2.3 2 0 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif VATC PF18716.1 CBK22246.2 - 0.26 11.1 4.6 0.27 11.1 3.8 1.5 1 1 0 1 1 1 0 Vms1-associating treble clef domain DSPc PF00782.20 CBK22247.2 - 5.6e-14 52.1 0.1 8.4e-14 51.5 0.1 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain AtuA PF07287.11 CBK22247.2 - 0.17 10.6 0.0 0.22 10.2 0.0 1.1 1 0 0 1 1 1 0 Acyclic terpene utilisation family protein AtuA CBP_BcsO PF17037.5 CBK22247.2 - 6.4 6.9 7.9 0.49 10.5 0.6 2.4 1 1 3 4 4 4 0 Cellulose biosynthesis protein BcsO Styelin PF17562.2 CBK22249.2 - 0.16 12.3 0.7 0.26 11.7 0.7 1.3 1 0 0 1 1 1 0 Styelin Ribosomal_L6e PF01159.19 CBK22250.2 - 4.8e-21 75.4 0.3 6.8e-11 42.7 0.0 2.1 1 1 1 2 2 2 2 Ribosomal protein L6e MDD_C PF18376.1 CBK22252.2 - 2.9e-52 177.1 0.1 3.6e-52 176.8 0.1 1.1 1 0 0 1 1 1 1 Mevalonate 5-diphosphate decarboxylase C-terminal domain GHMP_kinases_N PF00288.26 CBK22252.2 - 0.19 12.0 1.2 0.8 10.0 1.1 2.2 2 0 0 2 2 2 0 GHMP kinases N terminal domain DUF1664 PF07889.12 CBK22253.2 - 0.00014 21.9 2.0 0.00014 21.9 2.0 3.0 2 1 1 3 3 3 1 Protein of unknown function (DUF1664) Jnk-SapK_ap_N PF09744.9 CBK22253.2 - 0.004 17.4 39.1 0.037 14.3 10.9 3.1 2 1 1 3 3 3 2 JNK_SAPK-associated protein-1 TPR_MLP1_2 PF07926.12 CBK22253.2 - 0.0058 16.7 9.5 0.0058 16.7 9.5 2.8 2 1 1 3 3 3 2 TPR/MLP1/MLP2-like protein HrpB7 PF09486.10 CBK22253.2 - 0.019 15.4 3.7 0.019 15.4 3.7 3.4 2 1 0 2 2 1 0 Bacterial type III secretion protein (HrpB7) CENP-Q PF13094.6 CBK22253.2 - 0.021 15.0 2.0 0.021 15.0 2.0 3.8 2 2 1 3 3 2 0 CENP-Q, a CENPA-CAD centromere complex subunit Fez1 PF06818.15 CBK22253.2 - 0.13 12.8 32.1 0.096 13.1 8.2 2.3 2 0 0 2 2 2 0 Fez1 DUF4407 PF14362.6 CBK22253.2 - 0.17 11.2 21.7 0.24 10.7 6.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) HALZ PF02183.18 CBK22253.2 - 0.33 11.2 0.2 0.33 11.2 0.2 4.9 5 1 1 6 6 6 0 Homeobox associated leucine zipper GAS PF13851.6 CBK22253.2 - 0.45 9.8 38.0 0.57 9.5 8.0 3.3 2 2 0 2 2 2 0 Growth-arrest specific micro-tubule binding OmpH PF03938.14 CBK22253.2 - 0.6 10.4 34.0 1.3 9.3 15.6 2.6 2 1 0 2 2 2 0 Outer membrane protein (OmpH-like) KAR PF15222.6 CBK22253.2 - 0.94 9.8 4.6 0.47 10.8 1.7 2.0 2 0 0 2 2 2 0 Kidney androgen-regulated Shugoshin_N PF07558.11 CBK22253.2 - 2.9 7.8 15.6 0.78 9.7 0.3 4.5 4 1 0 4 4 4 0 Shugoshin N-terminal coiled-coil region Filament PF00038.21 CBK22253.2 - 2.9 7.4 30.9 0.23 11.0 6.6 2.7 2 1 0 2 2 2 0 Intermediate filament protein Atg14 PF10186.9 CBK22253.2 - 3.8 6.5 29.1 0.14 11.3 7.4 2.1 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 SOGA PF11365.8 CBK22253.2 - 4.2 8.6 24.7 0.34 12.1 3.7 3.5 2 1 2 4 4 3 0 Protein SOGA Mod_r PF07200.13 CBK22253.2 - 4.5 7.4 33.7 3 8.0 4.6 3.3 2 1 1 3 3 3 0 Modifier of rudimentary (Mod(r)) protein Formin_GBD_N PF18382.1 CBK22253.2 - 4.6 7.8 12.6 2.4 8.7 0.8 3.2 2 1 1 3 3 3 0 Formin N-terminal GTPase-binding domain CENP-H PF05837.12 CBK22253.2 - 4.9 7.6 41.0 0.62 10.5 7.3 3.9 2 2 2 4 4 4 0 Centromere protein H (CENP-H) APG6_N PF17675.1 CBK22253.2 - 5.3 7.6 43.9 37 4.8 12.3 3.9 2 2 0 2 2 2 0 Apg6 coiled-coil region MMPL PF03176.15 CBK22253.2 - 5.5 5.8 9.2 0.13 11.2 1.9 1.8 2 0 0 2 2 2 0 MMPL family YabA PF06156.13 CBK22253.2 - 6.5 7.4 31.7 1 10.0 2.9 4.2 2 2 2 4 4 4 0 Initiation control protein YabA Fib_alpha PF08702.10 CBK22253.2 - 7.8 6.7 28.0 0.17 12.0 2.2 3.2 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family BRCT_2 PF16589.5 CBK22254.2 - 1.1e-32 112.2 0.9 6.9e-16 58.4 0.1 4.3 4 0 0 4 4 4 4 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 CBK22254.2 - 1.2e-22 80.0 0.4 1.3e-10 41.5 0.0 5.0 4 1 0 4 4 4 3 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 CBK22254.2 - 4.7e-22 77.7 0.3 9e-10 38.4 0.0 3.6 4 0 0 4 4 4 2 twin BRCT domain LIG3_BRCT PF16759.5 CBK22254.2 - 0.0025 18.1 0.1 0.29 11.5 0.1 2.8 2 0 0 2 2 2 1 DNA ligase 3 BRCT domain adh_short PF00106.25 CBK22255.2 - 6.6e-09 35.5 0.0 1.3e-07 31.3 0.0 2.2 2 0 0 2 2 2 1 short chain dehydrogenase Epimerase PF01370.21 CBK22255.2 - 0.0096 15.4 0.1 0.036 13.5 0.0 1.8 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Terminase_6C PF17289.2 CBK22255.2 - 0.082 13.0 0.0 0.24 11.5 0.0 1.7 1 1 1 2 2 2 0 Terminase RNaseH-like domain Picorna_P3A PF06363.11 CBK22255.2 - 0.089 12.7 0.0 0.2 11.6 0.0 1.5 1 0 0 1 1 1 0 Picornaviridae P3A protein Peptidase_C78 PF07910.13 CBK22256.2 - 3.7e-43 147.5 0.1 5e-43 147.1 0.1 1.1 1 0 0 1 1 1 1 Peptidase family C78 Peptidase_C54 PF03416.19 CBK22256.2 - 4.7e-05 22.9 0.6 0.03 13.7 0.1 2.4 1 1 0 2 2 2 2 Peptidase family C54 DSPc PF00782.20 CBK22258.2 - 8.2e-06 25.7 0.0 9.6e-06 25.4 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 CBK22258.2 - 5.8e-05 22.8 0.0 7.1e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Cytochrom_NNT PF03264.14 CBK22258.2 - 0.024 14.3 0.1 1.6 8.4 0.0 2.1 2 0 0 2 2 2 0 NapC/NirT cytochrome c family, N-terminal region PTPlike_phytase PF14566.6 CBK22258.2 - 0.093 12.8 0.0 0.14 12.3 0.0 1.2 1 0 0 1 1 1 0 Inositol hexakisphosphate Ribosomal_S3Ae PF01015.18 CBK22259.2 - 2.2e-84 282.1 2.9 2.9e-84 281.7 2.9 1.1 1 0 0 1 1 1 1 Ribosomal S3Ae family SUI1 PF01253.22 CBK22259.2 - 0.0014 19.2 0.4 0.0059 17.1 0.3 2.2 1 1 1 2 2 2 1 Translation initiation factor SUI1 Abhydro_lipase PF04083.16 CBK22259.2 - 0.021 14.4 0.1 0.072 12.7 0.0 1.9 2 0 0 2 2 2 0 Partial alpha/beta-hydrolase lipase region DUF3395 PF11875.8 CBK22259.2 - 0.065 13.1 0.0 0.23 11.3 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3395) zf-RING_2 PF13639.6 CBK22261.2 - 2.2e-12 47.1 9.0 2.2e-12 47.1 9.0 2.5 3 0 0 3 3 2 1 Ring finger domain zf-RING_11 PF17123.5 CBK22261.2 - 2.9e-09 36.5 5.2 2.9e-09 36.5 5.2 2.4 2 0 0 2 2 2 1 RING-like zinc finger zf-RING_UBOX PF13445.6 CBK22261.2 - 1.3e-06 28.3 3.4 1.3e-06 28.3 3.4 3.0 3 0 0 3 3 3 1 RING-type zinc-finger zf-C3HC4 PF00097.25 CBK22261.2 - 2e-06 27.6 6.7 2e-06 27.6 6.7 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CBK22261.2 - 9.5e-06 25.5 6.9 9.5e-06 25.5 6.9 2.1 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 CBK22261.2 - 1.4e-05 24.8 9.0 1.4e-05 24.8 9.0 1.9 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) PA PF02225.22 CBK22261.2 - 2.2e-05 24.4 0.0 4.3e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 PA domain Prok-RING_4 PF14447.6 CBK22261.2 - 4.6e-05 23.2 7.2 4.6e-05 23.2 7.2 2.7 2 1 0 2 2 2 1 Prokaryotic RING finger family 4 zf-rbx1 PF12678.7 CBK22261.2 - 0.00039 20.6 9.1 0.0014 18.9 9.1 2.0 1 1 0 1 1 1 1 RING-H2 zinc finger domain Zn_ribbon_17 PF17120.5 CBK22261.2 - 0.0074 15.9 7.3 0.0074 15.9 7.3 2.0 2 1 0 2 2 2 1 Zinc-ribbon, C4HC2 type zf-C3HC4_3 PF13920.6 CBK22261.2 - 0.014 15.3 10.3 0.014 15.3 10.3 2.1 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) RINGv PF12906.7 CBK22261.2 - 0.056 13.6 3.7 0.16 12.1 3.7 1.8 1 1 0 1 1 1 0 RING-variant domain FANCL_C PF11793.8 CBK22261.2 - 0.066 13.4 10.3 0.11 12.7 7.0 2.8 2 1 0 2 2 2 0 FANCL C-terminal domain zf-ANAPC11 PF12861.7 CBK22261.2 - 0.081 13.0 6.1 0.26 11.4 6.1 1.9 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Rtf2 PF04641.12 CBK22261.2 - 0.1 11.9 3.0 0.16 11.3 3.0 1.3 1 0 0 1 1 1 0 Rtf2 RING-finger Prok-RING_1 PF14446.6 CBK22261.2 - 1.8 8.5 9.2 30 4.6 0.1 2.8 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 Mito_carr PF00153.27 CBK22262.2 - 1.3e-56 188.5 5.9 5.2e-24 84.0 0.3 4.1 3 1 1 4 4 4 4 Mitochondrial carrier protein DUP PF00674.18 CBK22263.2 - 0.057 13.6 0.2 4.8 7.4 0.0 2.2 2 0 0 2 2 2 0 DUP family eIF-5a PF01287.20 CBK22264.2 - 1.8e-15 56.7 2.1 2.7e-15 56.2 2.1 1.3 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold EFP_N PF08207.12 CBK22264.2 - 8.9e-05 22.4 0.1 0.00017 21.5 0.1 1.6 1 0 0 1 1 1 1 Elongation factor P (EF-P) KOW-like domain Pec_lyase PF09492.10 CBK22264.2 - 0.056 12.8 0.1 0.077 12.3 0.1 1.2 1 0 0 1 1 1 0 Pectic acid lyase Ribosomal_L7Ae PF01248.26 CBK22265.2 - 2e-27 94.8 0.0 2.5e-27 94.4 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family PELOTA_1 PF15608.6 CBK22265.2 - 0.0013 18.6 0.0 0.0019 18.1 0.0 1.3 1 0 0 1 1 1 1 PELOTA RNA binding domain RNase_P_pop3 PF08228.11 CBK22265.2 - 0.003 17.6 0.0 0.0032 17.5 0.0 1.1 1 0 0 1 1 1 1 RNase P subunit Pop3 Adenosine_kin PF04008.14 CBK22265.2 - 0.025 14.4 0.0 0.032 14.0 0.0 1.2 1 0 0 1 1 1 0 Adenosine specific kinase UPF0147 PF03685.13 CBK22265.2 - 0.083 13.0 0.0 0.17 12.0 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0147) Porin_3 PF01459.22 CBK22266.2 - 2.7e-18 66.4 3.0 3.4e-18 66.1 3.0 1.0 1 0 0 1 1 1 1 Eukaryotic porin MiAMP1 PF09117.10 CBK22266.2 - 0.2 11.9 2.6 8.7 6.7 0.1 2.7 3 0 0 3 3 3 0 MiAMP1 HA2 PF04408.23 CBK22267.2 - 1.3e-17 64.1 0.6 7.8e-17 61.5 0.0 2.5 2 0 0 2 2 2 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 CBK22267.2 - 1.3e-17 63.9 0.1 3.1e-17 62.7 0.1 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 CBK22267.2 - 2.8e-10 40.5 0.0 7.4e-10 39.2 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 CBK22267.2 - 7.1e-09 35.7 0.4 3.3e-08 33.5 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.6 CBK22267.2 - 1.6e-05 25.2 0.8 3e-05 24.3 0.0 1.8 2 0 0 2 2 1 1 AAA domain Collagen PF01391.18 CBK22267.2 - 0.0006 19.5 5.4 0.0006 19.5 5.4 3.9 3 1 1 4 4 3 2 Collagen triple helix repeat (20 copies) AAA_30 PF13604.6 CBK22267.2 - 0.0022 17.7 0.0 0.0059 16.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_23 PF13476.6 CBK22267.2 - 0.0047 17.5 3.3 0.14 12.7 0.1 2.7 2 1 1 3 3 3 1 AAA domain ABC_tran PF00005.27 CBK22267.2 - 0.0065 17.0 0.8 0.033 14.7 0.1 2.4 2 1 1 3 3 3 1 ABC transporter DUF2075 PF09848.9 CBK22267.2 - 0.012 14.8 0.0 0.026 13.8 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) ResIII PF04851.15 CBK22267.2 - 0.013 15.5 0.4 6.4 6.7 0.0 2.9 3 0 0 3 3 3 0 Type III restriction enzyme, res subunit ATPase PF06745.13 CBK22267.2 - 0.014 14.7 0.0 0.035 13.5 0.0 1.6 1 0 0 1 1 1 0 KaiC T2SSE PF00437.20 CBK22267.2 - 0.016 14.3 0.0 0.028 13.5 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_19 PF13245.6 CBK22267.2 - 0.033 14.5 0.0 0.093 13.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain PhoH PF02562.16 CBK22267.2 - 0.039 13.4 0.0 0.11 11.9 0.0 1.7 1 0 0 1 1 1 0 PhoH-like protein SRP54 PF00448.22 CBK22267.2 - 0.043 13.4 0.9 0.28 10.8 0.6 2.4 2 1 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_14 PF13173.6 CBK22267.2 - 0.087 12.9 0.3 1.3 9.1 0.3 2.4 1 1 0 1 1 1 0 AAA domain Flavi_DEAD PF07652.14 CBK22267.2 - 0.14 12.1 0.0 0.28 11.2 0.0 1.5 1 0 0 1 1 1 0 Flavivirus DEAD domain AAA_24 PF13479.6 CBK22267.2 - 0.31 10.8 1.8 0.49 10.1 0.0 2.1 2 0 0 2 2 2 0 AAA domain UFC1 PF08694.11 CBK22268.2 - 1.9e-76 254.9 0.1 2.1e-76 254.8 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-fold modifier-conjugating enzyme 1 UQ_con PF00179.26 CBK22268.2 - 8.3e-07 28.7 0.1 1.2e-06 28.3 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 CBK22268.2 - 0.0014 18.9 0.0 0.0018 18.6 0.0 1.3 1 0 0 1 1 1 1 RWD domain Mito_carr PF00153.27 CBK22270.2 - 1.6e-33 114.5 5.1 3.5e-17 62.1 0.1 2.4 3 0 0 3 3 3 2 Mitochondrial carrier protein Got1 PF04178.12 CBK22271.2 - 2e-21 76.5 17.8 2.4e-21 76.3 17.3 1.4 1 1 0 1 1 1 1 Got1/Sft2-like family QCR10 PF09796.9 CBK22271.2 - 0.13 12.3 1.9 0.24 11.5 0.3 2.2 3 0 0 3 3 3 0 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) Orf78 PF06024.12 CBK22271.2 - 0.25 11.7 0.8 0.45 10.8 0.0 1.9 2 0 0 2 2 2 0 Orf78 (ac78) DUF4293 PF14126.6 CBK22271.2 - 2.2 8.5 12.1 2.1 8.6 5.9 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4293) Ribosomal_S30 PF04758.14 CBK22272.2 - 8.2e-27 93.2 7.4 1.3e-26 92.5 7.4 1.3 1 0 0 1 1 1 1 Ribosomal protein S30 ubiquitin PF00240.23 CBK22272.2 - 8.3e-21 73.5 0.1 1.2e-20 73.0 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 CBK22272.2 - 2.7e-08 33.5 0.1 3.8e-08 33.0 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 CBK22272.2 - 8.1e-05 23.1 0.4 0.002 18.7 0.4 2.1 1 1 0 1 1 1 1 DUF2407 ubiquitin-like domain Rad60-SLD_2 PF13881.6 CBK22272.2 - 0.0013 18.8 0.3 0.0049 17.0 0.3 2.2 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_5 PF18037.1 CBK22272.2 - 0.0095 16.3 0.0 0.019 15.3 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-like domain Sde2_N_Ubi PF13019.6 CBK22272.2 - 0.016 15.1 0.4 0.027 14.3 0.4 1.4 1 1 0 1 1 1 0 Silencing defective 2 N-terminal ubiquitin domain Pkinase PF00069.25 CBK22274.2 - 4.3e-13 49.2 0.2 5.9e-13 48.8 0.2 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBK22274.2 - 7.3e-10 38.6 0.1 9.1e-10 38.2 0.1 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.22 CBK22274.2 - 1e-08 35.0 0.0 1.7e-08 34.3 0.0 1.4 1 1 0 1 1 1 1 RIO1 family Kdo PF06293.14 CBK22274.2 - 1.2e-06 28.0 0.0 4e-06 26.3 0.0 1.8 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CBK22274.2 - 3.7e-05 23.8 0.0 0.001 19.0 0.1 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family EcKinase PF02958.20 CBK22274.2 - 0.0002 20.8 0.1 0.00025 20.5 0.1 1.2 1 0 0 1 1 1 1 Ecdysteroid kinase WaaY PF06176.11 CBK22274.2 - 0.00034 20.3 0.4 0.00041 20.0 0.4 1.2 1 0 0 1 1 1 1 Lipopolysaccharide core biosynthesis protein (WaaY) Choline_kinase PF01633.20 CBK22274.2 - 0.052 13.1 0.2 0.088 12.4 0.2 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase DUF1679 PF07914.11 CBK22274.2 - 0.11 11.4 0.1 0.24 10.2 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1679) ANAPC4_WD40 PF12894.7 CBK22275.2 - 5e-06 26.7 1.6 1 9.7 0.1 5.4 4 2 2 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 CBK22275.2 - 0.00014 21.6 0.7 0.78 9.8 0.0 4.0 4 0 0 4 4 4 2 WD40-like Beta Propeller Repeat eIF2A PF08662.11 CBK22275.2 - 0.00017 21.6 0.1 6.5 6.6 0.0 4.3 2 1 1 4 4 4 2 Eukaryotic translation initiation factor eIF2A TFIIIC_delta PF12657.7 CBK22275.2 - 0.024 14.5 0.9 1.6 8.6 0.1 2.5 2 0 0 2 2 2 0 Transcription factor IIIC subunit delta N-term WD40 PF00400.32 CBK22275.2 - 0.035 15.0 5.5 1.2e+02 3.8 0.1 6.3 5 2 0 5 5 5 0 WD domain, G-beta repeat Nucleoporin2 PF04096.14 CBK22276.2 - 1e-19 71.1 0.0 1.5e-19 70.6 0.0 1.2 1 0 0 1 1 1 1 Nucleoporin autopeptidase Nuc_sug_transp PF04142.15 CBK22279.2 - 9.4e-13 48.0 3.3 1.3e-12 47.5 3.3 1.2 1 0 0 1 1 1 1 Nucleotide-sugar transporter EamA PF00892.20 CBK22279.2 - 4.9e-05 23.5 14.8 0.0051 17.0 6.9 2.2 2 0 0 2 2 2 2 EamA-like transporter family SDH_alpha PF03313.15 CBK22281.2 - 7.4e-76 255.2 7.7 9.5e-76 254.9 7.7 1.2 1 0 0 1 1 1 1 Serine dehydratase alpha chain SDH_beta PF03315.15 CBK22281.2 - 7.8e-28 97.8 0.4 1.2e-16 61.5 0.1 2.6 1 1 1 2 2 2 2 Serine dehydratase beta chain MmgE_PrpD PF03972.14 CBK22281.2 - 0.1 11.1 3.3 0.15 10.6 3.3 1.2 1 0 0 1 1 1 0 MmgE/PrpD family TPR_1 PF00515.28 CBK22282.2 - 4.3e-28 96.0 9.4 3.5e-05 23.4 0.1 6.3 6 0 0 6 6 6 6 Tetratricopeptide repeat TPR_2 PF07719.17 CBK22282.2 - 2.8e-24 83.2 9.4 0.0033 17.4 0.0 6.7 6 1 0 6 6 6 6 Tetratricopeptide repeat TPR_8 PF13181.6 CBK22282.2 - 8.8e-14 50.5 5.7 0.11 12.8 0.0 6.3 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_17 PF13431.6 CBK22282.2 - 5.4e-13 48.3 3.9 0.0024 18.1 0.2 5.4 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_11 PF13414.6 CBK22282.2 - 1.5e-11 43.8 3.6 0.00017 21.2 0.2 4.8 4 1 2 6 6 6 3 TPR repeat TPR_14 PF13428.6 CBK22282.2 - 4.6e-11 42.6 1.0 0.0027 18.4 0.0 5.0 3 1 2 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.6 CBK22282.2 - 2.4e-10 40.9 1.1 0.027 15.1 0.0 4.4 3 1 2 5 5 5 2 Tetratricopeptide repeat TPR_19 PF14559.6 CBK22282.2 - 3.2e-10 40.4 2.3 0.012 16.1 0.0 4.3 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_9 PF13371.6 CBK22282.2 - 5.7e-09 36.0 0.7 0.03 14.5 0.0 3.7 2 2 1 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.6 CBK22282.2 - 2.1e-08 34.4 5.8 0.00066 19.9 0.0 4.9 4 2 1 5 5 4 2 Tetratricopeptide repeat TPR_7 PF13176.6 CBK22282.2 - 2.5e-07 30.3 5.2 0.91 9.7 0.2 6.2 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_6 PF13174.6 CBK22282.2 - 0.0012 19.4 7.2 12 6.8 0.1 5.9 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_10 PF13374.6 CBK22282.2 - 0.0014 18.5 10.6 1.8 8.6 0.5 4.7 6 0 0 6 6 5 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 CBK22282.2 - 0.0021 18.1 5.4 5.5 7.2 0.1 5.0 5 0 0 5 5 5 1 Fis1 C-terminal tetratricopeptide repeat SHNi-TPR PF10516.9 CBK22282.2 - 0.1 12.0 0.0 0.59 9.6 0.0 2.2 2 0 0 2 2 2 0 SHNi-TPR MIT PF04212.18 CBK22282.2 - 0.29 11.2 3.2 48 4.1 0.1 4.0 4 1 0 4 4 4 0 MIT (microtubule interacting and transport) domain Cofilin_ADF PF00241.20 CBK22283.2 - 1.8e-38 131.0 0.1 2.5e-20 72.5 0.0 2.1 2 0 0 2 2 2 2 Cofilin/tropomyosin-type actin-binding protein PP_kinase_N PF13089.6 CBK22283.2 - 0.1 12.9 0.1 2.8 8.3 0.0 2.4 2 1 0 2 2 2 0 Polyphosphate kinase N-terminal domain Ras PF00071.22 CBK22284.2 - 7.2e-25 87.5 0.0 1.5e-24 86.5 0.0 1.5 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CBK22284.2 - 4e-11 43.2 0.0 8.2e-11 42.2 0.0 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase EF_assoc_2 PF08356.12 CBK22284.2 - 2e-09 37.3 0.0 5.7e-09 35.8 0.0 1.7 2 0 0 2 2 2 1 EF hand associated EF-hand_6 PF13405.6 CBK22284.2 - 3.7e-08 32.7 0.2 0.0039 17.0 0.1 2.6 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.32 CBK22284.2 - 2.9e-06 26.4 0.1 0.042 13.4 0.0 2.7 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 CBK22284.2 - 3.4e-06 27.4 0.1 0.079 13.4 0.0 2.5 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 CBK22284.2 - 0.0003 20.1 2.8 0.42 10.2 0.3 2.7 2 0 0 2 2 2 2 EF hand Arf PF00025.21 CBK22284.2 - 0.00035 20.1 0.0 0.0052 16.3 0.0 2.3 1 1 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 CBK22284.2 - 0.058 13.5 0.0 0.1 12.7 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase EF-hand_8 PF13833.6 CBK22284.2 - 0.17 11.8 0.7 14 5.6 0.1 2.6 2 0 0 2 2 2 0 EF-hand domain pair MORN PF02493.20 CBK22286.2 - 6.7e-05 22.5 19.7 0.0042 16.9 5.9 3.4 3 0 0 3 3 3 2 MORN repeat zf-C3HC4_3 PF13920.6 CBK22286.2 - 0.67 9.9 23.2 1.3 8.9 23.2 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Lipase_3 PF01764.25 CBK22287.2 - 5e-18 65.3 0.0 8.4e-18 64.6 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) DUF2974 PF11187.8 CBK22287.2 - 0.015 14.9 0.0 0.024 14.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) TPT PF03151.16 CBK22288.2 - 1e-11 44.7 11.1 1.1e-11 44.6 11.1 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 CBK22288.2 - 4.4e-05 23.7 19.1 0.00012 22.2 9.3 2.1 2 0 0 2 2 2 2 EamA-like transporter family UAA PF08449.11 CBK22288.2 - 0.0024 17.1 16.8 0.0047 16.2 16.8 1.4 1 1 0 1 1 1 1 UAA transporter family ThrE_2 PF12821.7 CBK22288.2 - 1.3 9.2 12.3 0.13 12.4 4.5 2.9 2 2 2 4 4 4 0 Threonine/Serine exporter, ThrE DUF4190 PF13828.6 CBK22288.2 - 1.8 8.4 7.6 1.3 8.8 0.1 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4190) Ribosomal_L1 PF00687.21 CBK22289.2 - 4.1e-44 150.8 5.8 5.4e-44 150.4 5.8 1.1 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family zf-TRAF_2 PF15965.5 CBK22289.2 - 0.067 13.7 1.5 0.38 11.2 0.5 2.1 2 0 0 2 2 2 0 TRAF-like zinc-finger CPSase_L_D2 PF02786.17 CBK22290.2 - 2.1e-72 243.0 0.0 3.5e-72 242.3 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 CBK22290.2 - 6.7e-44 148.9 0.0 1.7e-43 147.6 0.0 1.7 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 CBK22290.2 - 4.8e-36 123.1 0.0 1e-35 122.1 0.0 1.6 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.22 CBK22290.2 - 4.7e-18 64.8 0.2 1e-17 63.7 0.2 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme PCC_BT PF18140.1 CBK22290.2 - 1.8e-10 41.3 0.1 1.5e-05 25.4 0.0 2.5 1 1 1 2 2 2 2 Propionyl-coenzyme A carboxylase BT domain Biotin_lipoyl_2 PF13533.6 CBK22290.2 - 3.1e-08 33.3 0.1 1.6e-07 31.0 0.0 2.1 1 1 1 2 2 2 1 Biotin-lipoyl like Dala_Dala_lig_C PF07478.13 CBK22290.2 - 8.5e-08 32.0 0.1 3.8e-07 29.9 0.0 2.0 1 1 1 2 2 2 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 CBK22290.2 - 2.6e-05 23.9 0.0 5.6e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain DUF2118 PF09891.9 CBK22290.2 - 0.0023 17.9 0.0 0.0057 16.6 0.0 1.6 1 0 0 1 1 1 1 Uncharacterized protein conserved in archaea (DUF2118) GCV_H PF01597.19 CBK22290.2 - 0.0032 17.4 0.1 0.012 15.5 0.1 1.9 1 0 0 1 1 1 1 Glycine cleavage H-protein PTS_EIIA_1 PF00358.20 CBK22290.2 - 0.0038 17.0 0.0 0.01 15.6 0.0 1.8 1 0 0 1 1 1 1 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 Peptidase_M23 PF01551.22 CBK22290.2 - 0.028 14.6 0.1 0.3 11.3 0.0 2.3 2 0 0 2 2 2 0 Peptidase family M23 RnfC_N PF13375.6 CBK22290.2 - 0.053 13.5 0.0 0.13 12.3 0.0 1.6 1 0 0 1 1 1 0 RnfC Barrel sandwich hybrid domain PYNP_C PF07831.13 CBK22290.2 - 0.067 12.8 0.0 0.21 11.3 0.0 1.8 1 0 0 1 1 1 0 Pyrimidine nucleoside phosphorylase C-terminal domain HlyD_D23 PF16576.5 CBK22290.2 - 0.097 11.9 0.0 0.2 10.9 0.0 1.5 1 0 0 1 1 1 0 Barrel-sandwich domain of CusB or HlyD membrane-fusion HlyD_3 PF13437.6 CBK22290.2 - 0.12 13.1 0.1 0.49 11.1 0.0 2.2 2 0 0 2 2 1 0 HlyD family secretion protein RF-1 PF00472.20 CBK22292.2 - 8.9e-18 64.3 4.2 1.2e-17 63.8 4.2 1.2 1 0 0 1 1 1 1 RF-1 domain Exonuc_VII_S PF02609.16 CBK22293.2 - 0.0082 16.2 0.1 0.012 15.6 0.1 1.2 1 0 0 1 1 1 1 Exonuclease VII small subunit DHHC PF01529.20 CBK22295.2 - 6.9e-15 55.3 19.0 6.9e-15 55.3 19.0 2.5 2 1 0 2 2 2 1 DHHC palmitoyltransferase DUF1011 PF06237.12 CBK22295.2 - 0.55 10.6 10.1 0.048 14.0 4.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1011) CH PF00307.31 CBK22297.2 - 1.4e-29 102.5 0.2 9.5e-14 51.5 0.1 3.4 2 0 0 2 2 2 2 Calponin homology (CH) domain CAMSAP_CH PF11971.8 CBK22297.2 - 0.0013 18.5 0.0 2.5 8.0 0.0 2.8 2 0 0 2 2 2 2 CAMSAP CH domain DUF948 PF06103.11 CBK22297.2 - 0.023 15.0 15.0 0.8 10.0 0.4 4.9 3 1 1 4 4 4 0 Bacterial protein of unknown function (DUF948) OSTMP1 PF09777.9 CBK22297.2 - 0.053 12.9 0.8 0.17 11.3 0.8 1.9 1 0 0 1 1 1 0 Osteopetrosis-associated transmembrane protein 1 precursor Cation_ATPase_N PF00690.26 CBK22297.2 - 0.057 13.1 0.7 0.21 11.3 0.2 2.2 2 0 0 2 2 2 0 Cation transporter/ATPase, N-terminus LEM PF03020.15 CBK22297.2 - 0.063 12.9 0.0 7.2 6.3 0.0 2.9 1 1 1 2 2 2 0 LEM domain ApbE PF02424.15 CBK22297.2 - 0.64 9.5 1.9 0.7 9.4 0.1 2.0 2 1 0 2 2 2 0 ApbE family SieB PF14163.6 CBK22297.2 - 3.5 7.1 4.6 2 7.9 0.0 2.6 3 0 0 3 3 3 0 Super-infection exclusion protein B DUF2730 PF10805.8 CBK22297.2 - 3.6 7.7 14.2 0.058 13.5 0.8 3.7 1 1 3 4 4 4 0 Protein of unknown function (DUF2730) Thioredoxin PF00085.20 CBK22298.2 - 3.9e-63 209.9 0.1 2.2e-30 104.7 0.0 3.4 4 0 0 4 4 4 2 Thioredoxin Thioredoxin_6 PF13848.6 CBK22298.2 - 9e-33 113.7 0.0 5.2e-24 85.2 0.0 3.3 3 0 0 3 3 3 2 Thioredoxin-like domain Thioredoxin_2 PF13098.6 CBK22298.2 - 1.6e-11 44.6 0.2 0.0017 18.8 0.0 4.0 3 1 0 3 3 3 2 Thioredoxin-like domain Thioredoxin_7 PF13899.6 CBK22298.2 - 1.7e-09 37.7 0.0 0.0031 17.6 0.0 2.9 3 0 0 3 3 3 2 Thioredoxin-like AhpC-TSA PF00578.21 CBK22298.2 - 1.8e-07 31.1 0.1 0.015 15.2 0.0 2.8 3 0 0 3 3 3 2 AhpC/TSA family Thioredoxin_8 PF13905.6 CBK22298.2 - 1.9e-07 31.3 0.1 0.0051 17.1 0.0 3.7 4 1 1 5 5 5 2 Thioredoxin-like OST3_OST6 PF04756.13 CBK22298.2 - 5.5e-07 29.2 0.0 0.0019 17.6 0.0 2.4 2 0 0 2 2 2 2 OST3 / OST6 family, transporter family Redoxin PF08534.10 CBK22298.2 - 1.2e-06 28.3 0.4 0.019 14.7 0.0 3.2 3 0 0 3 3 3 1 Redoxin ERp29_N PF07912.13 CBK22298.2 - 1.3e-05 25.3 0.1 1.1 9.4 0.0 3.6 3 1 0 3 3 3 2 ERp29, N-terminal domain TraF PF13728.6 CBK22298.2 - 0.011 15.6 0.0 0.5 10.2 0.0 2.5 2 1 0 2 2 2 0 F plasmid transfer operon protein NIBRIN_BRCT_II PF16508.5 CBK22298.2 - 0.072 13.4 0.0 0.18 12.2 0.0 1.6 1 0 0 1 1 1 0 Second BRCT domain on Nijmegen syndrome breakage protein HyaE PF07449.11 CBK22298.2 - 0.1 12.6 0.2 9.6 6.2 0.0 3.4 4 0 0 4 4 4 0 Hydrogenase-1 expression protein HyaE Thioredoxin_9 PF14595.6 CBK22298.2 - 0.12 12.1 0.1 5.2 6.8 0.1 2.8 3 0 0 3 3 3 0 Thioredoxin Glutaredoxin PF00462.24 CBK22298.2 - 0.24 11.6 1.4 11 6.3 0.0 3.0 2 1 0 2 2 2 0 Glutaredoxin DUF3053 PF11254.8 CBK22299.2 - 0.03 13.9 0.2 0.03 13.9 0.2 3.3 2 1 1 4 4 4 0 Protein of unknown function (DUF3053) Sec7_N PF12783.7 CBK22300.2 - 2.8e-09 37.1 0.8 3.1e-09 36.9 0.8 1.1 1 0 0 1 1 1 1 Guanine nucleotide exchange factor in Golgi transport N-terminal Sec7 PF01369.20 CBK22301.2 - 5.5e-30 104.4 0.2 8e-30 103.9 0.2 1.3 1 0 0 1 1 1 1 Sec7 domain S4 PF01479.25 CBK22302.2 - 1.8e-12 46.8 0.4 1.8e-12 46.8 0.4 2.2 2 0 0 2 2 2 1 S4 domain zf-DBF PF07535.12 CBK22302.2 - 0.11 12.6 0.0 0.26 11.4 0.0 1.6 1 0 0 1 1 1 0 DBF zinc finger Met_10 PF02475.16 CBK22303.2 - 6.3e-29 101.1 0.0 1.5e-28 99.9 0.0 1.5 1 1 1 2 2 2 1 Met-10+ like-protein MTS PF05175.14 CBK22303.2 - 4.4e-06 26.3 0.1 2.8e-05 23.8 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase small domain Cons_hypoth95 PF03602.15 CBK22303.2 - 3.5e-05 23.5 0.0 4.7e-05 23.1 0.0 1.3 1 1 0 1 1 1 1 Conserved hypothetical protein 95 tRNA_U5-meth_tr PF05958.11 CBK22303.2 - 0.00018 20.6 0.1 0.00048 19.2 0.0 1.6 2 0 0 2 2 2 1 tRNA (Uracil-5-)-methyltransferase Methyltransf_25 PF13649.6 CBK22303.2 - 0.00023 21.8 0.0 0.00072 20.2 0.0 1.9 2 1 0 2 2 2 1 Methyltransferase domain PrmA PF06325.13 CBK22303.2 - 0.00072 19.0 0.0 0.0014 18.1 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_18 PF12847.7 CBK22303.2 - 0.0012 18.8 0.0 0.0023 17.9 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain RrnaAD PF00398.20 CBK22303.2 - 0.0021 17.2 0.0 0.003 16.7 0.0 1.3 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_15 PF09445.10 CBK22303.2 - 0.0042 16.7 0.0 0.0059 16.2 0.0 1.4 1 1 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_31 PF13847.6 CBK22303.2 - 0.0097 15.7 0.1 0.024 14.5 0.1 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltr_RsmB-F PF01189.17 CBK22303.2 - 0.026 14.2 0.0 0.044 13.4 0.0 1.3 1 0 0 1 1 1 0 16S rRNA methyltransferase RsmB/F AhpC-TSA PF00578.21 CBK22304.2 - 8e-36 122.7 0.0 1.1e-35 122.3 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 CBK22304.2 - 1.2e-11 44.6 0.0 1.5e-11 44.2 0.0 1.1 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.9 CBK22304.2 - 1.8e-11 43.7 0.0 3.8e-11 42.6 0.0 1.5 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin DUF3284 PF11687.8 CBK22305.2 - 0.1 12.5 0.0 19 5.2 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3284) Ephrin_rec_like PF07699.13 CBK22307.2 - 0.00021 21.0 1.8 0.00047 19.9 1.8 1.6 1 0 0 1 1 1 1 Putative ephrin-receptor like NCD3G PF07562.14 CBK22307.2 - 0.14 12.2 2.7 0.28 11.2 2.7 1.4 1 0 0 1 1 1 0 Nine Cysteines Domain of family 3 GPCR JAMP PF05571.12 CBK22307.2 - 0.45 10.1 1.7 0.62 9.6 1.7 1.1 1 0 0 1 1 1 0 JNK1/MAPK8-associated membrane protein eIF-3_zeta PF05091.12 CBK22308.2 - 7.7e-78 262.7 2.2 8.8e-78 262.5 2.2 1.0 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Ribosomal_L27 PF01016.19 CBK22309.2 - 3.6e-35 119.8 0.2 4.4e-35 119.6 0.2 1.1 1 0 0 1 1 1 1 Ribosomal L27 protein ArfGap PF01412.18 CBK22310.2 - 1.2e-26 93.1 0.1 2.7e-26 91.9 0.1 1.6 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf Pkinase PF00069.25 CBK22310.2 - 1.2e-18 67.5 0.0 5.2e-18 65.4 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain ANTH PF07651.16 CBK22310.2 - 3.1e-16 59.2 0.1 5.2e-16 58.5 0.1 1.3 1 0 0 1 1 1 1 ANTH domain Pkinase_Tyr PF07714.17 CBK22310.2 - 2.1e-08 33.8 0.0 3.8e-07 29.7 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CBK22310.2 - 0.00056 19.3 0.0 0.0012 18.2 0.0 1.5 1 0 0 1 1 1 1 Kinase-like DUF908 PF06012.12 CBK22310.2 - 0.014 14.8 0.6 0.028 13.8 0.6 1.5 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) DUF4887 PF16228.5 CBK22310.2 - 0.081 13.1 3.8 0.14 12.3 3.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4887) zf-B_box PF00643.24 CBK22310.2 - 0.21 11.8 0.3 0.38 11.0 0.3 1.4 1 0 0 1 1 1 0 B-box zinc finger Pkinase_Tyr PF07714.17 CBK22311.2 - 7.8e-63 212.2 0.0 1e-62 211.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 CBK22311.2 - 2.4e-52 177.9 0.0 3.2e-52 177.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Haspin_kinase PF12330.8 CBK22311.2 - 0.18 10.7 0.0 0.29 10.0 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Nitroreductase PF00881.24 CBK22313.2 - 3.6e-29 102.0 0.1 9.4e-29 100.6 0.1 1.7 1 1 0 1 1 1 1 Nitroreductase family TM1586_NiRdase PF14512.6 CBK22313.2 - 2.1e-15 56.9 0.9 4e-07 29.8 0.0 3.1 2 1 1 3 3 3 3 Putative TM nitroreductase Helicase_C PF00271.31 CBK22314.2 - 4.7e-19 68.8 0.2 2.7e-16 59.9 0.0 3.2 3 0 0 3 3 3 2 Helicase conserved C-terminal domain ResIII PF04851.15 CBK22314.2 - 7.1e-18 65.2 0.0 1.4e-17 64.2 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 CBK22314.2 - 5.9e-16 58.7 0.0 1.5e-15 57.4 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase SOUL PF04832.12 CBK22314.2 - 0.052 13.7 0.0 0.1 12.8 0.0 1.4 1 0 0 1 1 1 0 SOUL heme-binding protein zf-HC5HC2H_2 PF13832.6 CBK22316.2 - 2.3e-24 85.7 7.9 3.6e-24 85.1 7.9 1.3 1 0 0 1 1 1 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 CBK22316.2 - 1.5e-14 54.0 7.4 1.5e-14 54.0 7.4 1.7 2 0 0 2 2 2 1 PHD-like zinc-binding domain Adaptin_N PF01602.20 CBK22317.2 - 4.4e-139 464.4 15.1 5.3e-139 464.1 15.1 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 CBK22317.2 - 1.1e-62 210.8 13.8 2.8e-60 203.0 1.8 3.8 3 1 1 4 4 4 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 CBK22317.2 - 1.9e-18 66.6 1.9 8.5e-07 29.3 0.0 6.5 2 2 4 7 7 7 5 HEAT repeats HEAT PF02985.22 CBK22317.2 - 1.5e-11 43.5 5.6 0.0051 17.0 0.0 7.5 7 0 0 7 7 7 2 HEAT repeat Cnd3 PF12719.7 CBK22317.2 - 3.4e-08 33.0 0.9 3.9e-05 23.0 0.0 3.0 2 1 0 2 2 2 2 Nuclear condensing complex subunits, C-term domain RTP1_C1 PF10363.9 CBK22317.2 - 5.8e-08 32.9 4.0 0.00096 19.3 0.0 4.9 2 2 2 4 4 4 1 Required for nuclear transport of RNA pol II C-terminus 1 Arm PF00514.23 CBK22317.2 - 3e-05 23.9 0.6 0.24 11.5 0.0 4.8 5 0 0 5 5 5 1 Armadillo/beta-catenin-like repeat CLASP_N PF12348.8 CBK22317.2 - 0.00016 21.3 1.5 0.35 10.4 0.0 3.7 2 1 1 3 3 3 1 CLASP N terminal UNC45-central PF11701.8 CBK22317.2 - 0.0066 16.4 2.3 1.2 9.1 0.2 4.1 4 1 0 4 4 4 1 Myosin-binding striated muscle assembly central Arm_2 PF04826.13 CBK22317.2 - 0.022 14.2 1.2 0.21 11.0 0.0 2.5 2 0 0 2 2 2 0 Armadillo-like Sec7_N PF12783.7 CBK22317.2 - 0.024 14.5 4.3 0.076 12.9 0.3 3.2 2 1 0 3 3 3 0 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF913 PF06025.12 CBK22317.2 - 0.49 9.3 4.0 1 8.3 3.5 1.8 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) CNDH2_C PF16858.5 CBK22317.2 - 0.61 9.9 15.5 1.1 9.1 15.5 1.4 1 0 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term DUF5578 PF17741.1 CBK22317.2 - 4 6.8 10.5 4.1 6.8 0.4 4.2 3 1 1 5 5 5 0 Family of unknown function (DUF5578) Gar1 PF04410.14 CBK22318.2 - 5.5e-22 78.2 0.3 9e-22 77.5 0.3 1.3 1 0 0 1 1 1 1 Gar1/Naf1 RNA binding region Ribosomal_60s PF00428.19 CBK22319.2 - 6.3e-23 81.2 14.5 7.3e-23 81.0 14.5 1.0 1 0 0 1 1 1 1 60s Acidic ribosomal protein RNA_pol_3_Rpc31 PF11705.8 CBK22319.2 - 0.53 10.5 7.1 0.68 10.2 7.1 1.1 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 DUF4611 PF15387.6 CBK22319.2 - 0.61 10.3 7.4 1.3 9.3 7.3 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4611) Ribosomal_S4e PF00900.20 CBK22320.2 - 2.1e-32 110.8 0.7 6.5e-32 109.3 0.7 1.8 1 0 0 1 1 1 1 Ribosomal family S4e 40S_S4_C PF16121.5 CBK22320.2 - 5e-26 90.1 0.0 8.9e-26 89.3 0.0 1.4 1 0 0 1 1 1 1 40S ribosomal protein S4 C-terminus KOW PF00467.29 CBK22320.2 - 0.00011 22.1 2.1 0.00011 22.1 2.1 3.0 4 0 0 4 4 4 1 KOW motif S4 PF01479.25 CBK22320.2 - 0.0044 16.7 0.2 0.01 15.5 0.0 1.8 2 0 0 2 2 2 1 S4 domain DUF4056 PF13265.6 CBK22320.2 - 0.23 10.8 0.4 0.39 10.0 0.3 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF4056) zf-rbx1 PF12678.7 CBK22321.2 - 3.2e-20 72.2 10.3 8.7e-20 70.8 10.3 1.7 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 CBK22321.2 - 1.3e-14 54.0 11.9 9.5e-13 48.0 11.9 2.1 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_2 PF13923.6 CBK22321.2 - 1.7e-07 31.0 0.7 1.7e-07 31.0 0.7 2.5 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CBK22321.2 - 6.8e-07 29.5 12.6 0.00015 22.1 12.7 2.4 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 CBK22321.2 - 5.1e-05 23.1 8.2 9.5e-05 22.2 0.6 2.8 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 CBK22321.2 - 0.00014 21.4 8.2 0.00017 21.2 1.2 2.3 2 0 0 2 2 2 1 Zinc-ribbon, C4HC2 type zf-RING_11 PF17123.5 CBK22321.2 - 0.0069 16.1 1.3 0.0069 16.1 1.3 2.6 2 1 0 2 2 2 1 RING-like zinc finger FANCL_C PF11793.8 CBK22321.2 - 0.019 15.1 1.0 0.019 15.1 1.0 2.4 2 1 0 2 2 2 0 FANCL C-terminal domain zf-RING_UBOX PF13445.6 CBK22321.2 - 0.022 14.8 6.3 0.18 11.9 6.3 2.3 1 1 0 1 1 1 0 RING-type zinc-finger zf-Nse PF11789.8 CBK22321.2 - 0.042 13.7 0.1 0.073 12.9 0.1 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit DZR PF12773.7 CBK22321.2 - 0.046 13.8 1.9 0.11 12.6 1.9 1.6 1 0 0 1 1 1 0 Double zinc ribbon zf-C3HC4_3 PF13920.6 CBK22321.2 - 0.066 13.1 10.7 0.18 11.7 1.3 2.9 1 1 2 3 3 3 0 Zinc finger, C3HC4 type (RING finger) zf-HC5HC2H PF13771.6 CBK22321.2 - 0.11 12.7 9.1 0.33 11.2 2.1 2.2 1 1 1 2 2 2 0 PHD-like zinc-binding domain zf-RING_5 PF14634.6 CBK22321.2 - 0.68 9.9 10.6 18 5.4 10.7 2.4 1 1 0 1 1 1 0 zinc-RING finger domain zf-RING-like PF08746.11 CBK22321.2 - 2.8 8.3 11.4 29 5.1 11.4 2.2 1 1 0 1 1 1 0 RING-like domain PHD PF00628.29 CBK22321.2 - 4.8 7.2 10.1 1.2 9.0 0.8 2.3 2 0 0 2 2 2 0 PHD-finger EMP24_GP25L PF01105.24 CBK22322.2 - 4.1e-23 82.3 0.2 4.4e-23 82.2 0.2 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD RIO1 PF01163.22 CBK22323.2 - 4e-06 26.6 0.0 5.7e-06 26.1 0.0 1.4 1 1 0 1 1 1 1 RIO1 family Herpes_IE1 PF07340.11 CBK22323.2 - 0.013 14.5 0.1 0.014 14.3 0.1 1.0 1 0 0 1 1 1 0 Cytomegalovirus IE1 protein Suf PF05843.14 CBK22324.2 - 2.2e-08 34.5 0.1 2.6e-08 34.2 0.1 1.1 1 0 0 1 1 1 1 Suppressor of forked protein (Suf) TPR_14 PF13428.6 CBK22324.2 - 0.03 15.2 0.0 0.066 14.1 0.0 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_2 PF07719.17 CBK22324.2 - 0.032 14.3 0.2 0.093 12.9 0.0 1.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_15 PF13429.6 CBK22324.2 - 0.093 11.9 0.0 0.13 11.5 0.0 1.1 1 0 0 1 1 1 0 Tetratricopeptide repeat PPR_2 PF13041.6 CBK22324.2 - 0.15 12.3 0.0 0.27 11.4 0.0 1.4 1 0 0 1 1 1 0 PPR repeat family Fur_reg_FbpA PF13076.6 CBK22324.2 - 0.15 11.7 0.6 2.8 7.7 0.1 2.3 2 0 0 2 2 2 0 Fur-regulated basic protein A Fis1_TPR_C PF14853.6 CBK22324.2 - 0.31 11.2 1.4 1.5 9.0 0.0 2.3 2 0 0 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat Synaptobrevin PF00957.21 CBK22325.2 - 4e-11 42.5 1.4 7.5e-11 41.7 1.4 1.4 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.6 CBK22325.2 - 3.5e-09 36.6 0.4 8e-09 35.4 0.3 1.7 2 0 0 2 2 2 1 Regulated-SNARE-like domain TetR_C_29 PF17938.1 CBK22325.2 - 0.072 13.2 0.1 0.35 11.0 0.0 1.9 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain potato_inhibit PF00280.18 CBK22326.2 - 1.7e-18 67.0 0.2 2.3e-18 66.6 0.2 1.2 1 0 0 1 1 1 1 Potato inhibitor I family Ribosomal_L18 PF17135.4 CBK22327.2 - 2.6e-90 300.8 0.5 2.9e-90 300.7 0.5 1.0 1 0 0 1 1 1 1 Ribosomal protein 60S L18 and 50S L18e Ribosomal_L27A PF00828.19 CBK22327.2 - 0.0008 20.1 1.2 0.0015 19.2 0.0 2.1 2 1 0 2 2 2 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A OprF PF05736.11 CBK22327.2 - 0.15 11.8 0.0 0.3 10.8 0.0 1.4 1 1 0 1 1 1 0 OprF membrane domain Ribosomal_60s PF00428.19 CBK22328.2 - 6.3e-23 81.2 14.5 7.3e-23 81.0 14.5 1.0 1 0 0 1 1 1 1 60s Acidic ribosomal protein RNA_pol_3_Rpc31 PF11705.8 CBK22328.2 - 0.53 10.5 7.1 0.68 10.2 7.1 1.1 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 DUF4611 PF15387.6 CBK22328.2 - 0.61 10.3 7.4 1.3 9.3 7.3 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4611) ACC_central PF08326.12 CBK22329.2 - 1.4e-163 546.0 0.0 1.9e-163 545.4 0.0 1.2 1 0 0 1 1 1 1 Acetyl-CoA carboxylase, central region Carboxyl_trans PF01039.22 CBK22329.2 - 2e-152 508.3 0.8 3e-152 507.7 0.8 1.2 1 0 0 1 1 1 1 Carboxyl transferase domain CPSase_L_D2 PF02786.17 CBK22329.2 - 8.8e-48 162.6 0.4 6.1e-47 159.8 0.0 2.4 3 0 0 3 3 3 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Peptidase_C13 PF01650.18 CBK22329.2 - 3.9e-32 111.8 0.0 8.6e-32 110.7 0.0 1.5 1 0 0 1 1 1 1 Peptidase C13 family Biotin_carb_N PF00289.22 CBK22329.2 - 1.2e-29 103.1 0.1 3.6e-29 101.5 0.1 1.9 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 CBK22329.2 - 3.2e-24 85.1 0.2 2.9e-23 82.0 0.0 2.7 3 0 0 3 3 2 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.22 CBK22329.2 - 6.9e-11 41.8 0.0 3.2e-10 39.7 0.0 2.1 2 0 0 2 2 2 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.13 CBK22329.2 - 0.00042 19.9 0.0 0.0012 18.4 0.0 1.7 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 CBK22329.2 - 0.0015 18.2 0.0 0.0035 16.9 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.14 CBK22329.2 - 0.039 14.0 0.0 0.17 11.9 0.0 2.2 2 0 0 2 2 2 0 ATP-grasp domain ATPgrasp_ST PF14397.6 CBK22329.2 - 0.087 12.1 0.0 0.18 11.1 0.0 1.4 1 0 0 1 1 1 0 Sugar-transfer associated ATP-grasp Peptidase_C1 PF00112.23 CBK22330.2 - 1.7e-98 329.0 23.4 1.1e-55 189.0 5.8 2.1 2 0 0 2 2 2 2 Papain family cysteine protease Octopine_DH PF02317.17 CBK22330.2 - 0.032 14.3 0.0 0.17 12.0 0.0 1.9 2 0 0 2 2 2 0 NAD/NADP octopine/nopaline dehydrogenase, alpha-helical domain Peptidase_C1_2 PF03051.15 CBK22330.2 - 0.41 9.4 8.2 1.1 7.9 0.9 3.2 3 0 0 3 3 3 0 Peptidase C1-like family DUF2254 PF10011.9 CBK22331.2 - 0.068 12.0 0.0 0.093 11.5 0.0 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2254) NodZ PF05830.11 CBK22331.2 - 0.15 10.8 0.0 0.48 9.2 0.0 1.7 2 0 0 2 2 2 0 Nodulation protein Z (NodZ) Pex14_N PF04695.13 CBK22331.2 - 1.1 9.9 6.3 0.15 12.7 0.5 2.2 2 1 1 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region CDP-OH_P_transf PF01066.21 CBK22336.2 - 9.7e-16 58.3 0.3 9.7e-16 58.3 0.3 2.7 3 1 0 3 3 3 1 CDP-alcohol phosphatidyltransferase Phage_holin_1 PF04531.13 CBK22336.2 - 0.08 13.5 0.4 28 5.3 0.1 2.8 2 0 0 2 2 2 0 Bacteriophage holin TPT PF03151.16 CBK22337.2 - 1.5e-31 109.9 18.7 1.6e-31 109.7 18.7 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 CBK22337.2 - 9.2e-16 58.3 25.1 7.9e-10 39.0 15.1 2.2 2 0 0 2 2 2 2 EamA-like transporter family UAA PF08449.11 CBK22337.2 - 7.3e-05 22.1 22.9 0.00012 21.4 22.9 1.4 1 1 0 1 1 1 1 UAA transporter family Multi_Drug_Res PF00893.19 CBK22337.2 - 2.2 9.0 8.5 4 8.2 0.8 3.4 3 2 0 3 3 3 0 Small Multidrug Resistance protein TMEM234 PF10639.9 CBK22337.2 - 8.1 6.5 12.9 9.5 6.3 1.4 2.7 2 1 0 2 2 2 0 Putative transmembrane family 234 Phosducin PF02114.16 CBK22338.2 - 0.008 15.1 0.0 0.0085 15.1 0.0 1.0 1 0 0 1 1 1 1 Phosducin DUF4239 PF14023.6 CBK22339.2 - 2.3e-05 24.2 0.0 2.8e-05 24.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4239) DUF4306 PF14154.6 CBK22339.2 - 0.027 14.6 0.5 0.042 14.0 0.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4306) Renin_r PF07850.14 CBK22339.2 - 0.41 11.3 2.2 0.73 10.5 2.2 1.6 1 1 0 1 1 1 0 Renin receptor-like protein TINF2_N PF14973.6 CBK22340.2 - 0.2 12.0 0.4 22 5.4 0.1 2.2 2 0 0 2 2 2 0 TERF1-interacting nuclear factor 2 N-terminus NYD-SP28_assoc PF14775.6 CBK22341.2 - 0.22 11.6 4.8 0.87 9.7 0.6 2.4 2 0 0 2 2 2 0 Sperm tail C-terminal domain Swi5 PF07061.11 CBK22341.2 - 0.75 9.9 4.0 1.4 9.0 1.6 2.4 2 1 1 3 3 3 0 Swi5 Glyco_hydro_20 PF00728.22 CBK22342.2 - 5.1e-73 246.5 7.0 2.1e-71 241.2 7.0 2.3 1 1 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.6 CBK22342.2 - 2.4e-20 73.6 0.0 1.9e-19 70.7 0.0 2.4 1 1 0 1 1 1 1 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.15 CBK22342.2 - 4.4e-07 30.7 0.0 1e-06 29.5 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 Helicase_C PF00271.31 CBK22344.2 - 5.2e-11 42.9 0.0 1.2e-09 38.5 0.0 2.7 2 1 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 CBK22344.2 - 3.8e-09 36.6 0.0 9e-09 35.3 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 CBK22344.2 - 0.00038 20.5 0.0 0.00066 19.7 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SNF2_N PF00176.23 CBK22344.2 - 0.21 10.3 0.0 0.31 9.7 0.0 1.2 1 0 0 1 1 1 0 SNF2 family N-terminal domain Methyltr_RsmB-F PF01189.17 CBK22346.2 - 1.5e-39 135.7 0.0 2.5e-38 131.8 0.0 2.1 1 1 0 1 1 1 1 16S rRNA methyltransferase RsmB/F FtsJ PF01728.19 CBK22346.2 - 5e-08 33.3 0.0 9.2e-08 32.4 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase ThiF PF00899.21 CBK22347.2 - 1.4e-97 325.9 0.0 1.6e-66 224.1 0.0 2.5 2 1 0 2 2 2 2 ThiF family UBA_e1_thiolCys PF10585.9 CBK22347.2 - 3.7e-64 217.1 0.0 6.4e-64 216.3 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-activating enzyme active site E1_FCCH PF16190.5 CBK22347.2 - 2e-25 88.8 0.0 4.4e-25 87.7 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin-activating enzyme E1 FCCH domain E1_4HB PF16191.5 CBK22347.2 - 5.7e-16 58.5 0.0 1.5e-15 57.1 0.0 1.8 1 0 0 1 1 1 1 Ubiquitin-activating enzyme E1 four-helix bundle E1_UFD PF09358.10 CBK22347.2 - 9.2e-07 29.5 0.0 2.2e-06 28.3 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin fold domain Shikimate_DH PF01488.20 CBK22347.2 - 0.0098 16.0 1.1 1.9 8.5 0.1 2.4 2 0 0 2 2 2 2 Shikimate / quinate 5-dehydrogenase Plasmod_dom_1 PF09715.10 CBK22347.2 - 0.031 14.3 0.0 0.067 13.3 0.0 1.6 1 0 0 1 1 1 0 Plasmodium protein of unknown function (Plasmod_dom_1) Pyr_redox_2 PF07992.14 CBK22347.2 - 0.043 13.1 0.1 0.09 12.0 0.1 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase zf-RING_2 PF13639.6 CBK22348.2 - 1.8e-12 47.4 6.8 1.8e-12 47.4 6.8 1.9 2 0 0 2 2 1 1 Ring finger domain zf-RING_11 PF17123.5 CBK22348.2 - 1.6e-08 34.1 6.1 1.6e-08 34.1 6.1 2.4 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 CBK22348.2 - 1.8e-08 34.1 6.4 4.1e-08 32.9 6.4 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CBK22348.2 - 4.4e-08 32.9 5.3 1.2e-07 31.5 5.3 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) PA PF02225.22 CBK22348.2 - 1.8e-07 31.1 0.2 3.6e-07 30.1 0.2 1.5 1 0 0 1 1 1 1 PA domain zf-RING_5 PF14634.6 CBK22348.2 - 2.4e-07 30.6 4.2 2.4e-07 30.6 4.2 1.7 2 0 0 2 2 1 1 zinc-RING finger domain zf-rbx1 PF12678.7 CBK22348.2 - 2.5e-07 30.9 7.0 1.7e-06 28.2 7.0 2.3 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 CBK22348.2 - 6.4e-06 26.1 1.9 6.4e-06 26.1 1.9 2.6 3 0 0 3 3 2 1 RING-type zinc-finger zf-ANAPC11 PF12861.7 CBK22348.2 - 5e-05 23.3 3.2 0.00014 21.9 3.2 1.8 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.6 CBK22348.2 - 5.5e-05 22.9 2.7 0.00011 22.0 2.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 CBK22348.2 - 0.0018 17.9 2.4 0.0043 16.6 2.4 1.7 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type Prok-RING_4 PF14447.6 CBK22348.2 - 0.016 15.1 6.1 0.086 12.7 5.3 2.4 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 PHD PF00628.29 CBK22348.2 - 0.024 14.5 3.3 0.063 13.2 3.3 1.8 1 0 0 1 1 1 0 PHD-finger zf-Nse PF11789.8 CBK22348.2 - 0.026 14.3 6.6 0.039 13.8 4.0 2.3 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4_4 PF15227.6 CBK22348.2 - 0.031 14.4 5.3 0.096 12.9 5.3 1.9 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING YdjO PF14169.6 CBK22348.2 - 0.088 12.5 0.3 15 5.4 0.1 3.1 3 0 0 3 3 3 0 Cold-inducible protein YdjO zf-RING_4 PF14570.6 CBK22348.2 - 0.16 11.8 3.9 0.41 10.5 3.9 1.7 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain RINGv PF12906.7 CBK22348.2 - 0.43 10.7 4.1 1.1 9.4 4.1 1.8 1 0 0 1 1 1 0 RING-variant domain FANCL_C PF11793.8 CBK22348.2 - 0.44 10.8 6.9 0.33 11.2 4.0 2.3 2 1 0 2 2 2 0 FANCL C-terminal domain zf-C3H2C3 PF17122.5 CBK22348.2 - 0.45 10.6 8.6 8.5 6.5 2.4 3.7 3 1 0 3 3 3 0 Zinc-finger AAA_12 PF13087.6 CBK22349.2 - 3.7e-44 150.8 0.0 8.4e-44 149.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 CBK22349.2 - 2.7e-09 37.2 0.1 2.8e-07 30.6 0.0 2.6 1 1 2 3 3 3 1 AAA domain Viral_helicase1 PF01443.18 CBK22349.2 - 3.9e-06 26.8 0.0 0.014 15.1 0.0 2.5 2 0 0 2 2 2 2 Viral (Superfamily 1) RNA helicase UvrD_C_2 PF13538.6 CBK22349.2 - 0.028 14.3 0.0 0.064 13.1 0.0 1.6 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain UvrD_C PF13361.6 CBK22349.2 - 0.12 11.7 0.0 0.22 10.9 0.0 1.4 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain LUC7 PF03194.15 CBK22350.2 - 9.6e-58 195.8 4.5 9.6e-58 195.8 4.5 2.1 1 1 1 2 2 2 1 LUC7 N_terminus BUD22 PF09073.10 CBK22350.2 - 0.0013 18.2 22.8 0.0017 17.8 22.8 1.1 1 0 0 1 1 1 1 BUD22 HrcA PF01628.21 CBK22350.2 - 0.0014 18.6 1.0 0.0022 17.9 1.0 1.3 1 0 0 1 1 1 1 HrcA protein C terminal domain WD40_alt PF14077.6 CBK22350.2 - 0.46 10.4 2.1 4.5 7.2 0.4 2.5 2 0 0 2 2 2 0 Alternative WD40 repeat motif Adaptin_N PF01602.20 CBK22351.2 - 8.5e-84 282.0 6.5 1e-83 281.7 6.5 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 CBK22351.2 - 1.8e-36 125.6 3.4 3.8e-35 121.3 0.7 3.3 3 1 1 4 4 4 1 non-SMC mitotic condensation complex subunit 1 B2-adapt-app_C PF09066.10 CBK22351.2 - 1.4e-22 79.8 0.1 3.6e-22 78.6 0.1 1.7 1 0 0 1 1 1 1 Beta2-adaptin appendage, C-terminal sub-domain HEAT_2 PF13646.6 CBK22351.2 - 7.6e-10 39.1 2.5 5e-06 26.8 0.5 4.8 3 2 2 5 5 5 2 HEAT repeats HEAT PF02985.22 CBK22351.2 - 5.7e-07 29.2 1.6 0.88 10.0 0.0 5.3 4 0 0 4 4 4 2 HEAT repeat HEAT_EZ PF13513.6 CBK22351.2 - 0.0031 18.0 5.2 0.6 10.7 0.1 5.2 4 1 0 4 4 4 1 HEAT-like repeat API5 PF05918.11 CBK22351.2 - 0.0051 15.7 0.0 0.8 8.4 0.0 2.7 2 0 0 2 2 2 2 Apoptosis inhibitory protein 5 (API5) RTP1_C1 PF10363.9 CBK22351.2 - 0.029 14.5 0.1 0.7 10.1 0.0 3.3 2 1 0 2 2 2 0 Required for nuclear transport of RNA pol II C-terminus 1 DUF2937 PF11157.8 CBK22351.2 - 0.13 12.0 0.5 0.73 9.5 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2937) ABC_membrane PF00664.23 CBK22352.2 - 1.4e-55 188.9 15.4 8.6e-31 107.6 0.0 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 CBK22352.2 - 5.5e-50 169.5 1.5 1.1e-37 129.6 0.0 2.8 3 0 0 3 3 2 2 ABC transporter AAA_16 PF13191.6 CBK22352.2 - 1.3e-09 38.6 0.1 0.00054 20.4 0.0 2.7 2 0 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 CBK22352.2 - 1.1e-08 35.1 0.0 0.0052 16.7 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_29 PF13555.6 CBK22352.2 - 1.2e-08 34.5 0.1 0.0034 17.1 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 CBK22352.2 - 8.2e-08 32.6 1.4 0.0045 17.3 0.5 3.5 2 1 0 2 2 2 2 AAA domain SMC_N PF02463.19 CBK22352.2 - 1.9e-06 27.5 0.8 0.032 13.7 0.0 3.6 3 0 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_7 PF12775.7 CBK22352.2 - 3.3e-06 26.7 0.1 0.0045 16.5 0.0 2.4 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_23 PF13476.6 CBK22352.2 - 5.9e-06 26.9 15.1 0.028 14.9 0.0 3.4 3 0 0 3 3 3 2 AAA domain G-alpha PF00503.20 CBK22352.2 - 1.3e-05 24.5 0.5 0.088 11.9 0.0 2.6 3 0 0 3 3 3 2 G-protein alpha subunit AAA_15 PF13175.6 CBK22352.2 - 5.2e-05 23.1 9.6 0.48 10.1 0.0 3.1 2 1 0 2 2 2 2 AAA ATPase domain AAA_30 PF13604.6 CBK22352.2 - 5.9e-05 22.9 0.5 0.22 11.2 0.2 3.0 2 1 0 2 2 2 2 AAA domain AAA PF00004.29 CBK22352.2 - 8.9e-05 22.9 0.8 1.2 9.6 0.2 3.3 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 CBK22352.2 - 0.0001 22.3 0.4 1.3 9.0 0.0 3.5 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) CDC45 PF02724.14 CBK22352.2 - 0.00017 20.1 4.6 0.00028 19.3 4.6 1.3 1 0 0 1 1 1 1 CDC45-like protein MMR_HSR1 PF01926.23 CBK22352.2 - 0.00022 21.3 0.1 0.52 10.4 0.0 2.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase RNA_helicase PF00910.22 CBK22352.2 - 0.00044 20.6 0.3 2 8.8 0.0 3.3 3 0 0 3 3 3 1 RNA helicase AAA_11 PF13086.6 CBK22352.2 - 0.00046 20.1 2.3 0.0054 16.6 1.7 2.4 2 1 0 2 2 2 1 AAA domain Rad17 PF03215.15 CBK22352.2 - 0.00083 19.3 0.4 0.67 9.9 0.1 2.7 2 0 0 2 2 2 1 Rad17 P-loop domain Raftlin PF15250.6 CBK22352.2 - 0.00093 18.1 7.0 0.0017 17.2 7.0 1.3 1 0 0 1 1 1 1 Raftlin AAA_21 PF13304.6 CBK22352.2 - 0.00094 19.1 5.8 0.76 9.5 0.2 3.5 3 1 0 4 4 3 2 AAA domain, putative AbiEii toxin, Type IV TA system NB-ARC PF00931.22 CBK22352.2 - 0.00098 18.4 0.1 0.96 8.6 0.0 2.6 2 0 0 2 2 2 1 NB-ARC domain TniB PF05621.11 CBK22352.2 - 0.0011 18.4 0.1 6.6 6.1 0.0 3.2 3 0 0 3 3 3 0 Bacterial TniB protein AAA_25 PF13481.6 CBK22352.2 - 0.0016 18.1 0.1 0.76 9.3 0.0 3.0 3 0 0 3 3 3 1 AAA domain DEAD PF00270.29 CBK22352.2 - 0.0025 17.6 0.2 0.21 11.3 0.1 2.9 2 1 0 2 2 2 1 DEAD/DEAH box helicase AAA_33 PF13671.6 CBK22352.2 - 0.0025 18.0 0.1 3.1 7.9 0.0 2.7 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 CBK22352.2 - 0.0048 16.6 0.0 1.3 8.7 0.0 2.8 3 0 0 3 3 2 1 IstB-like ATP binding protein ABC_ATPase PF09818.9 CBK22352.2 - 0.0058 15.5 0.2 0.024 13.4 0.0 2.0 2 0 0 2 2 2 1 Predicted ATPase of the ABC class NACHT PF05729.12 CBK22352.2 - 0.0066 16.4 0.2 2 8.3 0.1 2.5 2 0 0 2 2 2 1 NACHT domain DUF87 PF01935.17 CBK22352.2 - 0.009 16.1 4.8 0.22 11.6 0.0 3.6 3 0 0 3 3 3 1 Helicase HerA, central domain Presenilin PF01080.17 CBK22352.2 - 0.012 14.5 0.0 0.012 14.5 0.0 2.5 2 0 0 2 2 2 0 Presenilin AAA_24 PF13479.6 CBK22352.2 - 0.012 15.3 1.3 1.1 8.9 0.2 2.8 2 1 0 2 2 2 0 AAA domain Connexin PF00029.19 CBK22352.2 - 0.013 15.3 2.4 0.03 14.1 2.4 1.6 1 0 0 1 1 1 0 Connexin MeaB PF03308.16 CBK22352.2 - 0.014 14.4 0.0 0.63 9.0 0.0 2.4 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB RNA_pol_Rpc4 PF05132.14 CBK22352.2 - 0.017 15.6 4.1 0.043 14.2 4.1 1.6 1 0 0 1 1 1 0 RNA polymerase III RPC4 Dynamin_N PF00350.23 CBK22352.2 - 0.018 15.1 2.2 12 5.9 0.3 3.4 3 0 0 3 3 3 0 Dynamin family KAP_NTPase PF07693.14 CBK22352.2 - 0.019 14.2 0.1 0.23 10.6 0.2 2.3 2 0 0 2 2 2 0 KAP family P-loop domain Roc PF08477.13 CBK22352.2 - 0.023 14.9 0.1 3.6 7.8 0.0 2.9 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase DUF913 PF06025.12 CBK22352.2 - 0.024 13.7 3.3 0.56 9.1 2.6 2.5 3 0 0 3 3 2 0 Domain of Unknown Function (DUF913) Sigma54_activat PF00158.26 CBK22352.2 - 0.029 14.1 0.0 4.1 7.1 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain MobB PF03205.14 CBK22352.2 - 0.03 14.2 0.1 4.7 7.1 0.1 2.5 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Sec62 PF03839.16 CBK22352.2 - 0.041 13.4 3.8 0.083 12.4 3.8 1.5 1 0 0 1 1 1 0 Translocation protein Sec62 Tim54 PF11711.8 CBK22352.2 - 0.041 12.7 9.3 0.072 11.9 9.3 1.3 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 ATP-synt_ab PF00006.25 CBK22352.2 - 0.048 13.3 0.0 3 7.4 0.0 2.4 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain DDHD PF02862.17 CBK22352.2 - 0.056 13.6 0.0 0.13 12.4 0.1 1.6 2 0 0 2 2 1 0 DDHD domain AAA_18 PF13238.6 CBK22352.2 - 0.073 13.6 11.0 0.65 10.5 0.1 3.8 4 0 0 4 4 3 0 AAA domain AAA_28 PF13521.6 CBK22352.2 - 0.081 13.2 0.6 4.3 7.5 0.0 2.8 2 0 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.18 CBK22352.2 - 0.09 12.1 0.1 1.6 8.0 0.0 2.6 3 0 0 3 3 3 0 FtsK/SpoIIIE family RR_TM4-6 PF06459.12 CBK22352.2 - 0.13 12.0 13.4 0.25 11.2 13.4 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 AAA_19 PF13245.6 CBK22352.2 - 0.15 12.4 0.6 13 6.1 0.1 3.1 3 1 0 3 3 2 0 AAA domain PRK PF00485.18 CBK22352.2 - 0.19 11.4 8.0 0.45 10.2 0.1 2.8 3 0 0 3 3 2 0 Phosphoribulokinase / Uridine kinase family CPSF100_C PF13299.6 CBK22352.2 - 0.2 11.8 5.7 0.38 10.9 5.7 1.4 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal NTPase_1 PF03266.15 CBK22352.2 - 0.22 11.4 2.3 14 5.6 0.0 2.9 3 0 0 3 3 2 0 NTPase Coilin_N PF15862.5 CBK22352.2 - 0.58 10.0 15.5 0.16 11.7 12.0 1.9 2 0 0 2 2 1 0 Coilin N-terminus Vfa1 PF08432.10 CBK22352.2 - 0.97 9.7 19.6 0.88 9.9 17.4 1.9 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 DUF4604 PF15377.6 CBK22352.2 - 1.1 9.7 22.9 2.5 8.5 22.9 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4604) DUF4337 PF14235.6 CBK22352.2 - 1.6 8.8 6.3 4.2 7.5 6.3 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) NPR3 PF03666.13 CBK22352.2 - 3.9 6.1 10.1 6.4 5.4 10.1 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 AIF_C PF14721.6 CBK22352.2 - 7.6 6.9 8.0 26 5.2 6.3 2.6 3 0 0 3 3 2 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Laminin_II PF06009.12 CBK22353.2 - 0.0064 16.5 4.3 0.0064 16.5 4.3 4.5 2 1 3 5 5 5 2 Laminin Domain II TMPIT PF07851.13 CBK22353.2 - 0.0087 15.3 7.7 0.0087 15.3 7.7 4.8 1 1 4 5 5 5 1 TMPIT-like protein DUF16 PF01519.16 CBK22353.2 - 0.023 15.2 7.9 0.023 15.2 7.9 5.5 2 2 3 5 5 5 0 Protein of unknown function DUF16 DUF1664 PF07889.12 CBK22353.2 - 2.8 8.0 44.2 0.55 10.3 9.6 5.0 1 1 3 5 5 5 0 Protein of unknown function (DUF1664) DUF948 PF06103.11 CBK22353.2 - 8.5 6.7 19.1 0.52 10.6 0.3 4.5 2 2 1 3 3 3 0 Bacterial protein of unknown function (DUF948) RRF PF01765.19 CBK22354.2 - 2e-27 96.1 15.1 2.7e-27 95.7 15.1 1.2 1 0 0 1 1 1 1 Ribosome recycling factor MtrG PF04210.13 CBK22354.2 - 0.029 14.2 1.0 0.059 13.2 1.0 1.5 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, subunit G TipAS PF07739.13 CBK22354.2 - 0.045 14.3 0.7 0.075 13.6 0.6 1.5 1 1 0 1 1 1 0 TipAS antibiotic-recognition domain YtxH PF12732.7 CBK22354.2 - 0.049 14.2 5.5 0.086 13.4 5.5 1.4 1 0 0 1 1 1 0 YtxH-like protein DUF4140 PF13600.6 CBK22354.2 - 0.14 12.6 3.0 0.35 11.3 2.9 2.0 1 1 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) DUF1204 PF06721.11 CBK22354.2 - 0.16 11.4 9.3 0.32 10.4 9.3 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1204) DUF1664 PF07889.12 CBK22354.2 - 1.3 9.1 9.2 1.1 9.4 7.2 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) PRKCSH-like PF12999.7 CBK22354.2 - 2.8 7.7 6.4 3.7 7.3 6.4 1.3 1 0 0 1 1 1 0 Glucosidase II beta subunit-like DUF1515 PF07439.11 CBK22354.2 - 3.3 7.8 7.3 6.2 6.9 7.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1515) RNase_H2-Ydr279 PF09468.10 CBK22355.2 - 1.5e-09 38.2 1.6 2.3e-09 37.6 1.6 1.4 1 1 0 1 1 1 1 Ydr279p protein family (RNase H2 complex component) wHTH domain Ydr279_N PF17745.1 CBK22355.2 - 1.1e-07 31.9 0.0 2.3e-07 31.0 0.0 1.5 1 0 0 1 1 1 1 Ydr279p protein triple barrel domain PP2C PF00481.21 CBK22356.2 - 1.5e-73 247.6 0.0 1.8e-73 247.4 0.0 1.0 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 CBK22356.2 - 0.0012 18.6 0.0 0.0017 18.0 0.0 1.5 1 1 0 1 1 1 1 Protein phosphatase 2C MCRS_N PF13325.6 CBK22357.2 - 0.022 14.8 4.2 0.022 14.8 4.2 2.0 2 0 0 2 2 2 0 N-terminal region of micro-spherule protein DnaJ PF00226.31 CBK22357.2 - 0.036 14.2 1.7 7.8 6.7 0.0 2.8 2 0 0 2 2 2 0 DnaJ domain MCU PF04678.13 CBK22357.2 - 6.5 6.8 11.8 0.4 10.8 1.2 2.3 2 0 0 2 2 2 0 Mitochondrial calcium uniporter LRR_4 PF12799.7 CBK22360.2 - 4.3 7.9 7.8 18 5.9 0.1 4.6 2 1 4 6 6 6 0 Leucine Rich repeats (2 copies) PRCC PF10253.9 CBK22360.2 - 9.6 6.9 11.4 18 6.1 11.4 1.4 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting Pkinase PF00069.25 CBK22361.2 - 2e-65 220.8 0.0 2.2e-65 220.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBK22361.2 - 7.7e-43 146.6 0.0 9.3e-43 146.4 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CBK22361.2 - 1.5e-08 34.3 0.0 2e-08 33.9 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 CBK22361.2 - 8.5e-07 28.5 0.0 1.3e-06 27.9 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 CBK22361.2 - 0.00021 20.2 0.0 0.00034 19.5 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase RIO1 PF01163.22 CBK22361.2 - 0.021 14.4 0.0 0.071 12.7 0.0 1.8 2 0 0 2 2 2 0 RIO1 family FTA2 PF13095.6 CBK22361.2 - 0.036 13.7 0.0 0.063 12.9 0.0 1.4 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 SH2_2 PF14633.6 CBK22362.2 - 1.8e-07 30.8 0.0 2.5e-07 30.3 0.0 1.1 1 0 0 1 1 1 1 SH2 domain CDC24_OB3 PF17244.2 CBK22363.2 - 0.0044 16.8 0.0 0.0046 16.7 0.0 1.0 1 0 0 1 1 1 1 Cell division control protein 24, OB domain 3 Fer2 PF00111.27 CBK22363.2 - 0.016 15.2 0.2 0.027 14.4 0.2 1.4 1 0 0 1 1 1 0 2Fe-2S iron-sulfur cluster binding domain OTT_1508_deam PF14441.6 CBK22363.2 - 0.46 10.5 2.5 1.2 9.1 0.2 2.0 1 1 1 2 2 2 0 OTT_1508-like deaminase eIF-3c_N PF05470.12 CBK22365.2 - 5.3e-51 173.6 0.4 6.7e-51 173.3 0.4 1.1 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 8 N-terminus PCI PF01399.27 CBK22365.2 - 2e-05 25.0 0.0 0.00063 20.2 0.0 2.5 2 0 0 2 2 2 1 PCI domain eIF-3c_N PF05470.12 CBK22366.2 - 4e-29 101.4 10.7 5.3e-29 101.0 10.7 1.1 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 8 N-terminus tRNA-synt_1e PF01406.19 CBK22366.2 - 0.0043 16.4 0.6 0.008 15.6 0.3 1.5 1 1 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain DUF1796 PF08795.10 CBK22366.2 - 0.0089 16.0 1.2 0.013 15.5 1.2 1.3 1 1 0 1 1 1 1 Putative papain-like cysteine peptidase (DUF1796) AbiJ_NTD5 PF18865.1 CBK22366.2 - 0.01 15.6 0.2 0.13 12.1 0.0 2.3 2 0 0 2 2 2 0 AbiJ N-terminal domain 5 MbeB_N PF04837.12 CBK22366.2 - 0.048 14.0 0.2 0.16 12.3 0.1 1.9 2 0 0 2 2 2 0 MbeB-like, N-term conserved region Spo0A_C PF08769.11 CBK22366.2 - 0.09 12.9 0.4 1.5 9.0 0.0 2.3 2 0 0 2 2 2 0 Sporulation initiation factor Spo0A C terminal HSCB_C PF07743.13 CBK22366.2 - 0.093 13.2 1.5 6.1 7.4 0.2 2.2 2 0 0 2 2 2 0 HSCB C-terminal oligomerisation domain Fib_alpha PF08702.10 CBK22366.2 - 0.12 12.6 0.3 0.12 12.6 0.3 2.0 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family IlvC PF01450.19 CBK22366.2 - 1.3 9.3 5.1 2 8.7 0.8 2.1 1 1 0 2 2 2 0 Acetohydroxy acid isomeroreductase, catalytic domain EXOSC1 PF10447.9 CBK22367.2 - 8.8e-15 55.3 2.5 8.4e-09 36.0 0.4 2.6 2 1 1 3 3 3 2 Exosome component EXOSC1/CSL4 ECR1_N PF14382.6 CBK22367.2 - 2.4e-09 36.8 0.0 5.3e-09 35.7 0.0 1.6 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region WD40 PF00400.32 CBK22368.2 - 6.2e-29 99.6 2.1 2.6e-07 31.2 0.0 6.1 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBK22368.2 - 4.8e-14 52.4 0.0 0.00011 22.4 0.0 3.5 2 1 1 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 CBK22368.2 - 1.8e-06 27.2 0.1 0.097 11.6 0.0 3.1 2 1 0 3 3 3 3 WD40 region of Ge1, enhancer of mRNA-decapping protein PIP5K PF01504.18 CBK22369.2 - 6.6e-81 271.5 1.6 2.5e-80 269.6 1.6 1.8 1 1 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase EF-hand_7 PF13499.6 CBK22370.2 - 3.4e-12 46.6 2.2 3.9e-10 40.0 2.0 2.8 2 1 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 CBK22370.2 - 1e-11 43.7 3.5 5.9e-06 25.8 0.3 3.2 3 0 0 3 3 3 2 EF-hand domain EF-hand_1 PF00036.32 CBK22370.2 - 4.2e-11 41.6 6.8 3.8e-07 29.2 0.9 2.7 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.6 CBK22370.2 - 2e-07 30.8 3.8 5.4e-05 22.9 0.1 2.6 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 CBK22370.2 - 3.8e-07 29.3 6.3 2.7e-06 26.6 0.4 2.5 2 0 0 2 2 2 2 EF hand EF-hand_4 PF12763.7 CBK22370.2 - 0.0092 15.9 1.6 0.13 12.2 0.1 2.4 1 1 1 2 2 2 1 Cytoskeletal-regulatory complex EF hand GerPC PF10737.9 CBK22370.2 - 0.072 13.1 0.1 0.21 11.7 0.0 1.7 1 1 0 1 1 1 0 Spore germination protein GerPC Topoisom_I PF01028.20 CBK22371.2 - 2.8e-90 301.6 1.3 5.1e-90 300.8 1.3 1.4 1 0 0 1 1 1 1 Eukaryotic DNA topoisomerase I, catalytic core Topoisom_I_N PF02919.15 CBK22371.2 - 2.2e-56 190.7 0.9 1.3e-55 188.2 0.0 2.3 3 0 0 3 3 3 1 Eukaryotic DNA topoisomerase I, DNA binding fragment Topo_C_assoc PF14370.6 CBK22371.2 - 1.1e-30 105.3 0.0 3.1e-30 103.9 0.0 1.8 1 0 0 1 1 1 1 C-terminal topoisomerase domain Lip_A_acyltrans PF03279.13 CBK22371.2 - 0.063 12.4 0.1 0.13 11.4 0.1 1.5 1 0 0 1 1 1 0 Bacterial lipid A biosynthesis acyltransferase ATP-grasp_5 PF13549.6 CBK22373.2 - 7.9e-54 182.4 0.1 1.1e-53 182.0 0.1 1.2 1 0 0 1 1 1 1 ATP-grasp domain CoA_binding_2 PF13380.6 CBK22373.2 - 1.1e-20 74.3 0.0 2.6e-20 73.1 0.0 1.7 1 0 0 1 1 1 1 CoA binding domain CoA_binding PF02629.19 CBK22373.2 - 5.9e-07 30.1 0.1 2.3e-06 28.2 0.1 2.1 2 0 0 2 2 2 1 CoA binding domain zf-MYND PF01753.18 CBK22374.2 - 2e-13 50.2 14.5 2.4e-13 49.9 14.5 1.1 1 0 0 1 1 1 1 MYND finger zf-C6H2 PF15801.5 CBK22374.2 - 0.00016 21.9 8.7 0.00026 21.2 8.7 1.4 1 1 0 1 1 1 1 zf-MYND-like zinc finger, mRNA-binding zf-HIT PF04438.16 CBK22374.2 - 0.0003 20.6 14.1 0.00069 19.4 10.9 2.1 2 0 0 2 2 2 1 HIT zinc finger Trm112p PF03966.16 CBK22374.2 - 0.077 13.6 0.8 0.12 12.9 0.8 1.3 1 0 0 1 1 1 0 Trm112p-like protein zf-Mss51 PF13824.6 CBK22374.2 - 6.5 6.9 10.6 26 5.0 10.6 1.8 1 1 1 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 Phage_holin_2_4 PF16082.5 CBK22375.2 - 0.053 13.3 0.1 0.12 12.1 0.1 1.6 1 0 0 1 1 1 0 Bacteriophage holin family, superfamily II-like PH_3 PF14593.6 CBK22376.2 - 1.1e-22 80.1 0.2 1.4e-22 79.7 0.2 1.1 1 0 0 1 1 1 1 PH domain Arf PF00025.21 CBK22377.2 - 3.4e-27 95.0 0.0 4e-27 94.8 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 CBK22377.2 - 4.8e-11 42.9 0.0 6e-11 42.6 0.0 1.1 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 CBK22377.2 - 2.1e-07 30.7 0.0 2.5e-07 30.4 0.0 1.1 1 0 0 1 1 1 1 Ras family SRPRB PF09439.10 CBK22377.2 - 4.5e-06 26.2 0.0 5.7e-06 25.9 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 CBK22377.2 - 1e-05 25.6 0.0 1.9e-05 24.7 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase G-alpha PF00503.20 CBK22377.2 - 0.00021 20.6 0.8 0.016 14.4 0.6 2.0 1 1 1 2 2 2 1 G-protein alpha subunit cobW PF02492.19 CBK22377.2 - 0.00077 19.1 0.3 0.0027 17.3 0.1 1.9 1 1 1 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain ABC_tran PF00005.27 CBK22377.2 - 0.0015 19.0 0.0 0.0018 18.8 0.0 1.2 1 0 0 1 1 1 1 ABC transporter FeoB_N PF02421.18 CBK22377.2 - 0.0034 16.9 0.0 0.091 12.3 0.0 2.1 2 0 0 2 2 2 1 Ferrous iron transport protein B AAA_23 PF13476.6 CBK22377.2 - 0.013 16.0 0.0 0.013 16.0 0.0 1.2 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 CBK22377.2 - 0.015 15.2 0.0 0.031 14.2 0.0 1.5 2 0 0 2 2 2 0 NTPase NACHT PF05729.12 CBK22377.2 - 0.02 14.8 0.0 0.081 12.8 0.0 1.9 1 1 0 1 1 1 0 NACHT domain RsgA_GTPase PF03193.16 CBK22377.2 - 0.022 14.7 0.0 0.036 14.0 0.0 1.3 1 0 0 1 1 1 0 RsgA GTPase RNA_helicase PF00910.22 CBK22377.2 - 0.035 14.5 0.0 0.11 12.9 0.0 1.8 1 1 0 1 1 1 0 RNA helicase AAA_22 PF13401.6 CBK22377.2 - 0.039 14.2 0.0 0.061 13.6 0.0 1.3 1 1 0 1 1 1 0 AAA domain Thymidylate_kin PF02223.17 CBK22377.2 - 0.056 13.1 0.0 0.056 13.1 0.0 1.3 1 0 0 1 1 1 0 Thymidylate kinase AAA_33 PF13671.6 CBK22377.2 - 0.08 13.1 0.0 0.17 12.1 0.0 1.8 1 1 0 1 1 1 0 AAA domain PEPCK_ATP PF01293.20 CBK22377.2 - 0.089 11.4 0.0 0.12 11.1 0.0 1.1 1 0 0 1 1 1 0 Phosphoenolpyruvate carboxykinase Septin PF00735.18 CBK22377.2 - 0.091 12.0 0.0 0.12 11.6 0.0 1.2 1 0 0 1 1 1 0 Septin SRP54 PF00448.22 CBK22377.2 - 0.18 11.4 0.0 0.5 10.0 0.0 1.7 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain DUF4379 PF14311.6 CBK22378.2 - 4.6e-47 158.2 30.3 1.9e-17 63.4 7.9 4.1 4 0 0 4 4 4 4 Probable Zinc-ribbon domain Zn-ribbon_8 PF09723.10 CBK22378.2 - 0.7 10.1 10.0 8.7 6.6 2.4 3.5 3 0 0 3 3 3 0 Zinc ribbon domain Rubredoxin_2 PF18073.1 CBK22378.2 - 2.5 7.9 23.8 0.16 11.7 1.3 5.7 5 0 0 5 5 5 0 Rubredoxin metal binding domain V-ATPase_C PF03223.15 CBK22379.2 - 3e-83 280.3 0.8 3.6e-83 280.0 0.8 1.0 1 0 0 1 1 1 1 V-ATPase subunit C DGF-1_C PF11040.8 CBK22379.2 - 0.13 12.3 0.2 0.25 11.3 0.2 1.5 1 0 0 1 1 1 0 Dispersed gene family protein 1 of Trypanosoma cruzi C-terminus DHHA2 PF02833.14 CBK22380.2 - 4.4e-12 46.4 3.1 8.3e-12 45.5 0.1 2.6 3 0 0 3 3 3 1 DHHA2 domain Methyltransf_23 PF13489.6 CBK22381.2 - 3.7e-22 78.9 0.0 5.8e-22 78.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CBK22381.2 - 6.3e-18 65.0 0.0 8.8e-18 64.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CBK22381.2 - 4.3e-15 56.3 0.0 1.1e-14 55.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CBK22381.2 - 7.5e-15 55.4 0.0 2.6e-14 53.7 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 CBK22381.2 - 7.5e-14 52.2 0.0 2.2e-13 50.7 0.0 1.8 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_9 PF08003.11 CBK22381.2 - 3.2e-10 39.4 0.0 5e-10 38.8 0.0 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF1698) MTS PF05175.14 CBK22381.2 - 7.1e-08 32.2 0.0 1.1e-07 31.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.13 CBK22381.2 - 2.9e-06 26.9 0.0 4.1e-06 26.4 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) CMAS PF02353.20 CBK22381.2 - 2.3e-05 23.8 0.0 4.8e-05 22.8 0.0 1.5 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_32 PF13679.6 CBK22381.2 - 8.3e-05 22.6 0.0 0.00011 22.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.7 CBK22381.2 - 0.00015 21.7 0.0 0.0021 18.0 0.0 2.3 3 0 0 3 3 3 1 Methyltransferase domain Ubie_methyltran PF01209.18 CBK22381.2 - 0.0021 17.4 0.0 0.024 14.0 0.0 2.0 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family FtsJ PF01728.19 CBK22381.2 - 0.0054 16.9 0.0 0.0084 16.2 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase RrnaAD PF00398.20 CBK22381.2 - 0.0063 15.6 0.0 0.0078 15.3 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase DOT1 PF08123.13 CBK22381.2 - 0.0067 16.0 0.0 0.012 15.1 0.0 1.4 1 0 0 1 1 1 1 Histone methylation protein DOT1 MetW PF07021.12 CBK22381.2 - 0.015 14.9 0.0 0.027 14.1 0.0 1.4 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW DREV PF05219.12 CBK22381.2 - 0.035 13.2 0.0 0.069 12.2 0.0 1.5 1 1 0 1 1 1 0 DREV methyltransferase Methyltransf_29 PF03141.16 CBK22381.2 - 0.05 12.2 0.0 0.1 11.1 0.0 1.5 1 1 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase AdoMet_MTase PF07757.13 CBK22381.2 - 0.08 13.3 0.0 0.13 12.6 0.0 1.3 1 0 0 1 1 1 0 Predicted AdoMet-dependent methyltransferase PCMT PF01135.19 CBK22381.2 - 0.1 12.4 0.0 0.15 11.8 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) pPIWI_RE_X PF13111.6 CBK22382.2 - 0.0064 15.7 0.0 0.45 9.7 0.0 2.0 1 1 1 2 2 2 2 pPIWI_RE module N-terminal domain DUF4050 PF13259.6 CBK22382.2 - 0.092 13.1 2.0 6.2 7.1 0.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF4050) Syndecan PF01034.20 CBK22383.2 - 0.12 12.3 0.1 0.18 11.8 0.1 1.3 1 0 0 1 1 1 0 Syndecan domain Ufm1 PF03671.14 CBK22384.2 - 6.5e-37 125.5 0.0 1.2e-36 124.7 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin fold modifier 1 protein Acyltransferase PF01553.21 CBK22384.2 - 3.3e-13 49.4 0.0 7.5e-13 48.3 0.0 1.6 1 0 0 1 1 1 1 Acyltransferase Peptidase_C1 PF00112.23 CBK22386.2 - 2.1e-11 44.3 0.1 5.1e-11 43.1 0.1 1.6 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 CBK22386.2 - 0.003 18.0 2.1 0.0048 17.3 0.7 2.1 2 0 0 2 2 2 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1 PF00112.23 CBK22387.2 - 6.5e-12 46.0 0.0 1.6e-11 44.7 0.0 1.6 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 CBK22387.2 - 0.0034 17.8 2.4 0.0045 17.4 1.0 2.0 2 0 0 2 2 2 1 Cathepsin propeptide inhibitor domain (I29) AMP-binding PF00501.28 CBK22388.2 - 0.00084 18.0 0.0 0.0011 17.7 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme FtsJ PF01728.19 CBK22389.2 - 7.4e-56 189.0 0.3 1.9e-55 187.7 0.1 1.8 2 0 0 2 2 2 1 FtsJ-like methyltransferase DUF3381 PF11861.8 CBK22389.2 - 1.3e-38 132.4 12.1 1.3e-38 132.4 12.1 5.1 3 1 0 3 3 3 1 Domain of unknown function (DUF3381) Spb1_C PF07780.12 CBK22389.2 - 3.1e-37 128.3 22.4 3.1e-37 128.3 22.4 4.4 3 3 0 3 3 3 1 Spb1 C-terminal domain Methyltr_RsmB-F PF01189.17 CBK22389.2 - 0.047 13.3 0.0 0.19 11.4 0.0 2.0 1 0 0 1 1 1 0 16S rRNA methyltransferase RsmB/F Collagen PF01391.18 CBK22389.2 - 1.8 8.4 9.2 0.54 10.1 2.1 2.3 2 0 0 2 2 2 0 Collagen triple helix repeat (20 copies) GCV_T PF01571.21 CBK22390.2 - 2.4e-77 259.8 0.0 3.4e-77 259.3 0.0 1.2 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.11 CBK22390.2 - 2.7e-24 84.9 0.2 8.6e-24 83.3 0.2 1.8 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain SoxG PF04268.12 CBK22390.2 - 0.14 12.3 0.0 0.45 10.7 0.0 1.8 2 0 0 2 2 2 0 Sarcosine oxidase, gamma subunit family Yip1 PF04893.17 CBK22391.2 - 3.2e-08 33.5 14.0 3.2e-08 33.5 14.0 1.8 1 1 1 2 2 2 1 Yip1 domain Wound_ind PF08186.11 CBK22392.2 - 0.081 13.4 0.0 0.13 12.7 0.0 1.4 1 0 0 1 1 1 0 Wound-inducible basic protein family Ipi1_N PF12333.8 CBK22393.2 - 9.1e-08 32.6 2.3 1e-06 29.2 0.2 3.0 3 0 0 3 3 3 1 Rix1 complex component involved in 60S ribosome maturation KLRAQ PF10205.9 CBK22393.2 - 0.22 11.8 3.1 0.53 10.6 0.4 2.6 2 0 0 2 2 2 0 Predicted coiled-coil domain-containing protein BPL_LplA_LipB PF03099.19 CBK22396.2 - 6.8e-11 42.2 0.0 9.8e-11 41.7 0.0 1.2 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family HpaB_N PF11794.8 CBK22396.2 - 0.17 11.5 0.0 0.26 10.9 0.0 1.2 1 0 0 1 1 1 0 4-hydroxyphenylacetate 3-hydroxylase N terminal DUF1765 PF08578.10 CBK22397.2 - 5.1e-14 52.8 3.4 5.1e-14 52.8 3.4 2.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1765) RCC1 PF00415.18 CBK22398.2 - 1.1e-30 106.0 5.5 1.4e-10 41.6 0.0 3.7 4 1 0 4 4 4 3 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 CBK22398.2 - 3e-16 58.7 3.5 5.7e-05 22.8 0.0 4.2 4 0 0 4 4 4 4 Regulator of chromosome condensation (RCC1) repeat Tachylectin PF14517.6 CBK22398.2 - 0.086 12.4 0.0 0.14 11.7 0.0 1.4 1 1 0 1 1 1 0 Tachylectin RCC1 PF00415.18 CBK22399.2 - 0.052 14.2 0.1 0.15 12.7 0.1 1.8 1 0 0 1 1 1 0 Regulator of chromosome condensation (RCC1) repeat RecR PF02132.15 CBK22399.2 - 0.082 12.5 0.3 0.13 11.8 0.3 1.3 1 0 0 1 1 1 0 RecR protein 2Fe-2S_thioredx PF01257.19 CBK22400.2 - 8.9e-59 197.5 1.0 1.2e-58 197.1 1.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like [2Fe-2S] ferredoxin Hexokinase_2 PF03727.16 CBK22401.2 - 3.3e-67 226.4 0.0 4.1e-67 226.1 0.0 1.1 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.21 CBK22401.2 - 2.2e-44 151.7 0.0 3.1e-44 151.3 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Acyl_transf_3 PF01757.22 CBK22402.2 - 0.058 12.4 36.0 0.44 9.6 35.9 3.0 1 1 0 1 1 1 0 Acyltransferase family Sensor PF13796.6 CBK22402.2 - 0.069 13.2 0.2 0.069 13.2 0.2 3.4 4 0 0 4 4 4 0 Putative sensor DUF2568 PF10823.8 CBK22402.2 - 5.2 7.4 9.5 8.3 6.8 0.2 4.1 3 1 1 4 4 4 0 Protein of unknown function (DUF2568) RmlD_sub_bind PF04321.17 CBK22403.2 - 0.0014 17.8 0.0 0.0014 17.8 0.0 1.0 1 0 0 1 1 1 1 RmlD substrate binding domain Glutaredoxin PF00462.24 CBK22404.2 - 5.9e-18 64.8 0.0 2.6e-17 62.8 0.0 2.0 3 0 0 3 3 3 1 Glutaredoxin Rubredoxin_C PF18267.1 CBK22404.2 - 0.12 12.3 0.0 0.24 11.3 0.0 1.5 1 0 0 1 1 1 0 Rubredoxin NAD+ reductase C-terminal domain eIF3g PF12353.8 CBK22405.2 - 1.3e-13 51.4 0.2 2.7e-13 50.4 0.2 1.5 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit G RRM_1 PF00076.22 CBK22405.2 - 4.8e-09 35.9 0.0 7.7e-09 35.3 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Alpha_L_fucos PF01120.17 CBK22406.2 - 2e-27 96.6 0.7 3.3e-27 95.9 0.7 1.3 1 0 0 1 1 1 1 Alpha-L-fucosidase F5_F8_type_C PF00754.25 CBK22406.2 - 1.5e-07 31.6 0.0 2.9e-07 30.7 0.0 1.4 1 0 0 1 1 1 1 F5/8 type C domain GHL6 PF14871.6 CBK22406.2 - 0.0029 17.7 0.0 0.0054 16.9 0.0 1.4 1 0 0 1 1 1 1 Hypothetical glycosyl hydrolase 6 ANAPC16 PF17256.2 CBK22406.2 - 0.16 12.4 0.0 0.31 11.4 0.0 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex, subunit 16 Toxin_32 PF08120.11 CBK22406.2 - 0.22 11.4 1.6 0.44 10.4 1.6 1.5 1 0 0 1 1 1 0 Tamulustoxin family LRR_5 PF13306.6 CBK22407.2 - 0.00065 19.7 1.4 0.0011 19.0 1.4 1.3 1 0 0 1 1 1 1 BspA type Leucine rich repeat region (6 copies) LRR_4 PF12799.7 CBK22407.2 - 0.017 15.5 6.2 1.9 9.0 0.3 4.2 1 1 2 3 3 3 0 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CBK22407.2 - 0.029 14.1 1.6 0.78 9.6 0.0 3.3 3 1 1 4 4 4 0 Leucine rich repeat LRR_1 PF00560.33 CBK22407.2 - 2.2 9.2 4.3 97 4.1 0.0 4.1 3 1 0 3 3 3 0 Leucine Rich Repeat RNA_pol_Rpc4 PF05132.14 CBK22408.2 - 1.6e-14 54.6 0.7 7e-14 52.5 0.7 1.9 1 1 0 1 1 1 1 RNA polymerase III RPC4 Suf PF05843.14 CBK22409.2 - 1.5e-15 58.0 14.3 6.4e-05 23.1 0.3 5.7 4 1 1 5 5 5 5 Suppressor of forked protein (Suf) TPR_14 PF13428.6 CBK22409.2 - 4.8e-10 39.4 11.9 1.6 9.8 0.0 10.8 11 2 2 13 13 12 2 Tetratricopeptide repeat TPR_15 PF13429.6 CBK22409.2 - 3.5e-08 33.0 2.1 0.37 9.9 0.0 5.6 3 2 2 5 5 5 3 Tetratricopeptide repeat TPR_19 PF14559.6 CBK22409.2 - 1.9e-05 25.1 0.3 8.6 7.0 0.0 6.3 7 0 0 7 7 7 1 Tetratricopeptide repeat NRDE-2 PF08424.10 CBK22409.2 - 3.3e-05 23.2 18.6 0.0037 16.5 1.4 5.4 5 2 0 5 5 5 2 NRDE-2, necessary for RNA interference TPR_8 PF13181.6 CBK22409.2 - 0.00026 21.0 7.4 3.1 8.2 0.1 6.4 7 1 1 8 8 7 2 Tetratricopeptide repeat HAT PF02184.16 CBK22409.2 - 0.001 19.0 6.3 4.2 7.4 0.0 5.8 6 0 0 6 6 6 1 HAT (Half-A-TPR) repeat TPR_2 PF07719.17 CBK22409.2 - 0.0014 18.6 17.9 0.025 14.6 0.1 8.1 10 0 0 10 10 9 1 Tetratricopeptide repeat TPR_21 PF09976.9 CBK22409.2 - 0.018 14.8 0.5 36 4.0 0.0 4.8 5 0 0 5 5 5 0 Tetratricopeptide repeat-like domain TPR_12 PF13424.6 CBK22409.2 - 0.019 15.2 3.6 8.1 6.8 0.0 5.5 6 1 1 7 7 7 0 Tetratricopeptide repeat Mad3_BUB1_I PF08311.12 CBK22409.2 - 0.041 13.8 21.1 1.5 8.8 0.2 7.0 7 2 1 8 8 8 0 Mad3/BUB1 homology region 1 TPR_17 PF13431.6 CBK22409.2 - 0.12 12.9 2.2 11 6.6 0.1 4.5 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_6 PF13174.6 CBK22409.2 - 0.81 10.5 6.6 61 4.6 0.0 5.7 8 0 0 8 8 6 0 Tetratricopeptide repeat TPR_7 PF13176.6 CBK22409.2 - 7.7 6.8 8.1 11 6.3 0.0 5.3 7 0 0 7 7 6 0 Tetratricopeptide repeat Big_5 PF13205.6 CBK22410.2 - 0.00029 21.5 1.0 0.13 13.0 0.0 3.0 3 0 0 3 3 3 2 Bacterial Ig-like domain DENN PF02141.21 CBK22411.2 - 8.5e-19 68.2 4.0 1.4e-18 67.5 2.6 2.0 2 1 0 2 2 2 1 DENN (AEX-3) domain Cyclin_N PF00134.23 CBK22413.2 - 2.2e-12 46.8 0.1 3.1e-12 46.3 0.1 1.2 1 0 0 1 1 1 1 Cyclin, N-terminal domain MFS_1 PF07690.16 CBK22414.2 - 2.1e-13 49.9 7.6 9.3e-13 47.8 7.6 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 CBK22414.2 - 0.0065 15.4 0.5 0.0065 15.4 0.5 2.1 2 1 1 3 3 3 1 Sugar (and other) transporter zf-C2H2 PF00096.26 CBK22415.2 - 1e-07 32.0 27.1 0.0093 16.4 0.7 6.0 6 0 0 6 6 6 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CBK22415.2 - 4.4e-05 24.0 27.8 0.014 16.1 0.6 6.0 6 0 0 6 6 6 3 C2H2-type zinc finger Tropomyosin_1 PF12718.7 CBK22415.2 - 0.019 15.1 0.4 0.034 14.3 0.4 1.3 1 0 0 1 1 1 0 Tropomyosin like zf-Di19 PF05605.12 CBK22415.2 - 0.033 14.5 1.4 0.033 14.5 1.4 3.2 2 1 1 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding zf-met PF12874.7 CBK22415.2 - 0.046 14.1 0.7 0.046 14.1 0.7 4.3 3 1 0 3 3 3 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 CBK22415.2 - 0.046 14.0 0.3 0.046 14.0 0.3 3.7 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 CBK22415.2 - 0.57 10.2 14.0 0.69 10.0 0.5 4.2 4 0 0 4 4 4 0 C2H2-type zinc finger FlhC PF05280.11 CBK22415.2 - 0.65 9.7 4.2 1.6 8.4 4.2 1.7 1 0 0 1 1 1 0 Flagellar transcriptional activator (FlhC) Zf_RING PF16744.5 CBK22415.2 - 3.3 7.9 9.2 1 9.5 3.2 3.0 2 1 1 3 3 3 0 KIAA1045 RING finger HLH PF00010.26 CBK22416.2 - 8.3e-09 35.3 1.5 1.5e-08 34.5 1.5 1.4 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain PAS_8 PF13188.7 CBK22416.2 - 0.0019 18.2 0.0 0.0041 17.1 0.0 1.5 1 0 0 1 1 1 1 PAS domain PAS PF00989.25 CBK22416.2 - 0.0037 17.3 0.0 0.0083 16.1 0.0 1.6 1 0 0 1 1 1 1 PAS fold PAS_3 PF08447.12 CBK22416.2 - 0.0096 16.2 0.0 0.018 15.3 0.0 1.4 1 0 0 1 1 1 1 PAS fold PAS_4 PF08448.10 CBK22416.2 - 0.09 13.0 0.0 0.18 12.1 0.0 1.4 1 0 0 1 1 1 0 PAS fold DUF1221 PF06760.11 CBK22416.2 - 0.1 12.0 0.1 0.15 11.5 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1221) COPIIcoated_ERV PF07970.12 CBK22417.2 - 4.1e-45 154.3 0.0 4.9e-45 154.1 0.0 1.0 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter Baseplate_J PF04865.14 CBK22418.2 - 0.1 11.7 0.0 0.15 11.2 0.0 1.2 1 0 0 1 1 1 0 Baseplate J-like protein pP_pnuc_2 PF18166.1 CBK22419.2 - 0.02 14.9 0.2 0.04 14.0 0.2 1.5 1 0 0 1 1 1 0 Predicted pPIWI-associating nuclease DUF842 PF05811.13 CBK22419.2 - 0.023 14.4 0.9 0.15 11.7 0.9 2.2 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF842) Ferritin PF00210.24 CBK22419.2 - 0.039 13.9 1.1 0.15 12.0 0.3 2.1 1 1 1 2 2 2 0 Ferritin-like domain Phage_GP20 PF06810.11 CBK22419.2 - 0.1 12.4 3.0 5.3 6.8 0.0 3.0 1 1 2 3 3 3 0 Phage minor structural protein GP20 TBCC_N PF16752.5 CBK22419.2 - 0.11 12.9 6.4 3.6 8.1 1.1 2.8 1 1 2 3 3 3 0 Tubulin-specific chaperone C N-terminal domain GAS PF13851.6 CBK22419.2 - 0.12 11.7 4.1 0.038 13.3 0.7 1.7 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding Bac_surface_Ag PF01103.23 CBK22420.2 - 6.4e-07 29.2 0.1 8.4e-07 28.8 0.1 1.1 1 0 0 1 1 1 1 Surface antigen TIM PF00121.18 CBK22421.2 - 2.1e-83 279.5 0.1 3.9e-83 278.6 0.1 1.4 1 0 0 1 1 1 1 Triosephosphate isomerase Gp_dh_C PF02800.20 CBK22421.2 - 2.4e-67 225.5 0.0 1.4e-66 222.9 0.0 2.1 2 0 0 2 2 2 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 CBK22421.2 - 3.1e-34 117.3 0.0 7.7e-34 116.1 0.0 1.7 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain CutC PF03932.14 CBK22421.2 - 0.042 13.3 0.0 0.091 12.2 0.0 1.5 1 0 0 1 1 1 0 CutC family GIDA PF01134.22 CBK22422.2 - 8.4e-136 453.1 0.0 1.2e-135 452.6 0.0 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A GIDA_assoc PF13932.6 CBK22422.2 - 3.5e-56 190.7 0.1 4.7e-56 190.3 0.1 1.2 1 0 0 1 1 1 1 GidA associated domain FAD_oxidored PF12831.7 CBK22422.2 - 1.5e-10 41.0 0.7 6.1e-09 35.7 0.3 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 CBK22422.2 - 6.6e-08 32.1 0.5 2.2e-07 30.4 0.5 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 CBK22422.2 - 5e-05 22.6 3.7 7.9e-05 21.9 3.2 1.6 2 0 0 2 2 2 1 FAD binding domain AlaDh_PNT_C PF01262.21 CBK22422.2 - 0.00012 21.5 0.2 0.0003 20.2 0.2 1.6 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox PF00070.27 CBK22422.2 - 0.00073 20.1 0.5 0.002 18.7 0.5 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 CBK22422.2 - 0.0016 17.8 0.0 0.013 14.7 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 CBK22422.2 - 0.0061 16.2 0.3 0.91 9.0 0.3 2.4 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.17 CBK22422.2 - 0.013 14.8 0.2 0.025 13.8 0.2 1.4 1 0 0 1 1 1 0 Thi4 family HI0933_like PF03486.14 CBK22422.2 - 0.018 13.8 2.8 0.035 12.8 1.7 1.9 2 0 0 2 2 2 0 HI0933-like protein FAD_binding_3 PF01494.19 CBK22422.2 - 0.12 11.5 0.5 0.21 10.8 0.5 1.3 1 0 0 1 1 1 0 FAD binding domain Lycopene_cycl PF05834.12 CBK22422.2 - 0.53 9.3 2.2 0.58 9.1 0.7 1.7 2 0 0 2 2 2 0 Lycopene cyclase protein Stc1 PF12898.7 CBK22423.2 - 0.031 14.8 7.5 0.058 13.9 7.5 1.4 1 0 0 1 1 1 0 Stc1 domain zf-C2H2 PF00096.26 CBK22424.2 - 1.4 9.5 4.3 9.4 6.9 0.2 2.7 3 0 0 3 3 3 0 Zinc finger, C2H2 type Pkinase PF00069.25 CBK22425.2 - 1.7e-25 89.9 0.0 2e-25 89.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBK22425.2 - 2e-14 53.5 0.0 2.5e-14 53.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CBK22425.2 - 6.8e-08 31.7 0.1 1.1e-07 31.0 0.1 1.3 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 CBK22425.2 - 0.0017 18.3 0.2 0.0032 17.4 0.2 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.11 CBK22425.2 - 0.08 11.9 0.1 0.11 11.4 0.1 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase EGF_2 PF07974.13 CBK22426.2 - 7.9e-30 102.9 130.7 2.1e-05 24.8 11.2 10.0 10 0 0 10 10 10 8 EGF-like domain EGF PF00008.27 CBK22426.2 - 3.4e-07 30.4 92.6 0.0024 18.2 2.0 8.7 8 0 0 8 8 8 5 EGF-like domain zf-RanBP PF00641.18 CBK22426.2 - 3.8e-07 29.3 3.4 2e-06 27.0 3.4 2.4 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others DSL PF01414.19 CBK22426.2 - 0.0021 18.3 17.3 0.0021 18.3 17.3 7.5 1 1 7 8 8 8 3 Delta serrate ligand EGF_alliinase PF04863.13 CBK22426.2 - 0.0098 16.3 8.7 0.0098 16.3 8.7 9.5 7 2 3 10 10 10 3 Alliinase EGF-like domain EB PF01683.18 CBK22426.2 - 0.022 15.0 3.2 0.022 15.0 3.2 9.4 6 2 3 9 9 9 0 EB module DnaJ PF00226.31 CBK22427.2 - 3.4e-07 30.3 0.0 5.9e-07 29.5 0.0 1.3 1 0 0 1 1 1 1 DnaJ domain Pam16 PF03656.13 CBK22427.2 - 3.6e-06 27.0 0.0 5.3e-06 26.5 0.0 1.2 1 0 0 1 1 1 1 Pam16 DUF1891 PF09004.10 CBK22427.2 - 0.073 12.7 1.1 5.7 6.6 0.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1891) DUF4444 PF14563.6 CBK22428.2 - 0.16 11.6 0.0 0.37 10.5 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4444) XPG_I PF00867.18 CBK22429.2 - 7.7e-20 71.1 1.1 1.4e-19 70.2 0.0 2.0 2 0 0 2 2 2 1 XPG I-region XPG_N PF00752.17 CBK22429.2 - 1.1e-05 25.8 0.1 2.1e-05 24.9 0.1 1.5 1 0 0 1 1 1 1 XPG N-terminal domain Laminin_II PF06009.12 CBK22430.2 - 0.042 13.9 13.3 0.4 10.7 2.8 2.4 1 1 1 2 2 2 0 Laminin Domain II M PF02370.16 CBK22430.2 - 0.1 13.2 2.5 0.1 13.2 2.5 5.0 4 1 0 4 4 4 0 M protein repeat IFP_35_N PF07334.13 CBK22430.2 - 0.1 12.7 13.8 1.2 9.3 1.7 3.7 2 1 1 3 3 3 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus AAA_13 PF13166.6 CBK22430.2 - 0.16 10.6 16.4 0.028 13.1 7.1 2.1 1 1 1 2 2 2 0 AAA domain CLZ PF16526.5 CBK22430.2 - 0.17 12.3 14.0 1.3 9.4 3.2 3.0 1 1 2 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Tnp_22_trimer PF17489.2 CBK22430.2 - 0.2 11.6 0.1 0.2 11.6 0.1 3.6 4 0 0 4 4 3 0 L1 transposable element trimerization domain ORF6C PF10552.9 CBK22430.2 - 0.22 11.6 10.3 0.48 10.5 1.4 2.5 2 1 0 2 2 2 0 ORF6C domain NPV_P10 PF05531.12 CBK22430.2 - 0.24 11.9 3.8 15 6.1 3.8 2.7 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein SlyX PF04102.12 CBK22430.2 - 0.28 11.8 10.6 4.4 8.0 2.5 2.8 1 1 1 2 2 2 0 SlyX Ax_dynein_light PF10211.9 CBK22430.2 - 0.34 10.8 24.4 2.1 8.3 11.5 2.5 1 1 1 2 2 2 0 Axonemal dynein light chain FlxA PF14282.6 CBK22430.2 - 0.43 10.6 13.4 0.37 10.8 5.2 2.7 1 1 1 2 2 2 0 FlxA-like protein Exonuc_VII_L PF02601.15 CBK22430.2 - 0.87 9.1 9.3 1.1 8.7 9.3 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit Tropomyosin_1 PF12718.7 CBK22430.2 - 1.3 9.2 30.4 0.41 10.8 23.8 2.4 1 1 1 2 2 2 0 Tropomyosin like ABC_tran_CTD PF16326.5 CBK22430.2 - 1.4 9.2 24.9 0.28 11.5 8.5 3.9 1 1 1 2 2 1 0 ABC transporter C-terminal domain Fzo_mitofusin PF04799.13 CBK22430.2 - 1.4 8.4 14.0 5.3 6.6 9.2 2.2 1 1 1 2 2 2 0 fzo-like conserved region Fib_alpha PF08702.10 CBK22430.2 - 1.5 9.0 18.6 0.2 11.8 10.8 2.3 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family DUF1664 PF07889.12 CBK22430.2 - 1.6 8.7 14.2 1.1 9.3 7.4 2.4 2 1 1 3 3 2 0 Protein of unknown function (DUF1664) DUF4407 PF14362.6 CBK22430.2 - 1.7 7.9 9.0 23 4.2 9.0 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Het-C PF07217.11 CBK22430.2 - 2.1 6.8 7.6 2.5 6.5 7.6 1.2 1 0 0 1 1 1 0 Heterokaryon incompatibility protein Het-C ALMT PF11744.8 CBK22430.2 - 2.2 7.0 10.3 3.2 6.5 10.3 1.3 1 0 0 1 1 1 0 Aluminium activated malate transporter UPF0242 PF06785.11 CBK22430.2 - 2.6 8.1 27.1 0.12 12.5 1.5 2.2 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Seryl_tRNA_N PF02403.22 CBK22430.2 - 3 8.1 21.3 3.3 8.0 9.1 2.9 2 1 1 3 3 3 0 Seryl-tRNA synthetase N-terminal domain FemAB PF02388.16 CBK22430.2 - 3 6.6 8.6 0.87 8.4 5.8 1.5 1 1 1 2 2 2 0 FemAB family Atg14 PF10186.9 CBK22430.2 - 3.4 6.7 17.3 3.6 6.6 16.3 1.5 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF1192 PF06698.11 CBK22430.2 - 3.4 7.8 9.1 3.1 7.9 0.2 2.8 3 0 0 3 3 2 0 Protein of unknown function (DUF1192) LMBR1 PF04791.16 CBK22430.2 - 3.7 6.3 12.7 4.3 6.1 12.7 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein DivIC PF04977.15 CBK22430.2 - 4.1 7.3 14.9 0.56 10.0 1.8 3.0 1 1 1 2 2 2 0 Septum formation initiator Swi5 PF07061.11 CBK22430.2 - 4.4 7.5 13.5 6.6e+03 -2.7 13.3 3.4 1 1 0 1 1 0 0 Swi5 Spc7 PF08317.11 CBK22430.2 - 5.2 5.9 27.6 4.9 5.9 3.8 1.9 1 1 1 2 2 2 0 Spc7 kinetochore protein DUF3450 PF11932.8 CBK22430.2 - 5.2 6.3 16.5 6.4 6.0 15.1 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) 5_nucleotid PF05761.14 CBK22430.2 - 5.6 5.7 15.5 43 2.8 15.4 1.9 1 1 0 1 1 1 0 5' nucleotidase family WD40_alt PF14077.6 CBK22430.2 - 6.5 6.7 12.0 2.3 8.1 1.7 3.4 2 2 2 4 4 4 0 Alternative WD40 repeat motif DUF1515 PF07439.11 CBK22430.2 - 7.1 6.7 6.7 1.9 8.6 1.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1515) IF4E PF01652.18 CBK22433.2 - 2.3e-44 151.0 0.9 2.7e-44 150.8 0.9 1.0 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E FtsX_ECD PF18075.1 CBK22433.2 - 0.16 12.6 0.0 1.4 9.6 0.0 2.0 2 0 0 2 2 2 0 FtsX extracellular domain FAD_binding_2 PF00890.24 CBK22434.2 - 4e-121 405.0 3.1 5.3e-121 404.6 3.1 1.2 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.20 CBK22434.2 - 2.4e-44 150.4 1.8 3.5e-44 149.9 1.8 1.3 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term Thi4 PF01946.17 CBK22434.2 - 5.1e-06 25.9 0.1 0.0067 15.7 0.1 2.6 3 0 0 3 3 3 2 Thi4 family GIDA PF01134.22 CBK22434.2 - 5.4e-05 22.4 0.9 0.003 16.7 1.0 2.2 2 0 0 2 2 2 1 Glucose inhibited division protein A Pyr_redox_2 PF07992.14 CBK22434.2 - 0.0001 21.6 0.3 0.00029 20.2 0.2 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 CBK22434.2 - 0.00023 20.9 0.4 0.00039 20.1 0.4 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 CBK22434.2 - 0.00023 20.5 0.2 0.00041 19.7 0.2 1.4 1 0 0 1 1 1 1 FAD binding domain NAD_binding_7 PF13241.6 CBK22434.2 - 0.019 15.4 0.0 0.8 10.2 0.0 2.4 2 0 0 2 2 2 0 Putative NAD(P)-binding HI0933_like PF03486.14 CBK22434.2 - 0.029 13.1 1.6 0.051 12.3 0.3 2.0 3 0 0 3 3 3 0 HI0933-like protein Ribosomal_L13 PF00572.18 CBK22435.2 - 1.3e-08 35.1 0.0 3.1e-08 33.9 0.0 1.7 1 1 0 1 1 1 1 Ribosomal protein L13 PRP21_like_P PF12230.8 CBK22437.2 - 4.7e-21 75.7 7.6 8.8e-19 68.2 7.6 2.1 1 1 0 1 1 1 1 Pre-mRNA splicing factor PRP21 like protein Surp PF01805.20 CBK22437.2 - 2.8e-08 33.6 0.0 5e-08 32.8 0.0 1.4 1 0 0 1 1 1 1 Surp module MBOAT PF03062.19 CBK22438.2 - 8.2e-25 87.9 12.1 8.2e-25 87.9 12.1 2.3 2 1 0 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family FANCI_S2 PF14676.6 CBK22438.2 - 0.0097 16.2 0.5 0.03 14.7 0.1 1.9 2 1 1 3 3 3 1 FANCI solenoid 2 ATP_bind_1 PF03029.17 CBK22439.2 - 1.5e-73 247.6 0.4 2.1e-73 247.1 0.4 1.2 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein GTP_EFTU PF00009.27 CBK22439.2 - 1e-05 25.2 0.0 0.0073 15.9 0.0 2.3 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 CBK22439.2 - 1.8e-05 24.8 0.0 0.0001 22.4 0.0 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 CBK22439.2 - 4.6e-05 23.9 0.0 5.8e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain FeoB_N PF02421.18 CBK22439.2 - 5.7e-05 22.7 0.3 0.0055 16.2 0.0 2.4 2 1 0 2 2 2 1 Ferrous iron transport protein B SRP54 PF00448.22 CBK22439.2 - 0.00015 21.4 0.2 0.00051 19.7 0.1 1.9 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain CLP1_P PF16575.5 CBK22439.2 - 0.00019 21.3 0.1 0.00086 19.2 0.0 1.9 2 0 0 2 2 2 1 mRNA cleavage and polyadenylation factor CLP1 P-loop Zeta_toxin PF06414.12 CBK22439.2 - 0.00025 20.4 0.0 0.00035 19.9 0.0 1.2 1 0 0 1 1 1 1 Zeta toxin RsgA_GTPase PF03193.16 CBK22439.2 - 0.00031 20.7 0.0 1.6 8.6 0.0 3.1 3 0 0 3 3 3 2 RsgA GTPase AAA_30 PF13604.6 CBK22439.2 - 0.00085 19.1 0.0 0.0015 18.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain NB-ARC PF00931.22 CBK22439.2 - 0.0011 18.2 0.0 0.002 17.3 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain MeaB PF03308.16 CBK22439.2 - 0.0013 17.8 0.0 0.055 12.4 0.0 2.1 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB CbiA PF01656.23 CBK22439.2 - 0.0017 18.4 0.0 0.0032 17.5 0.0 1.5 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_24 PF13479.6 CBK22439.2 - 0.0018 18.0 0.1 0.0062 16.3 0.0 1.9 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 CBK22439.2 - 0.0029 17.5 0.0 0.0053 16.7 0.0 1.4 1 0 0 1 1 1 1 NACHT domain PduV-EutP PF10662.9 CBK22439.2 - 0.0047 16.7 0.2 0.071 12.9 0.0 2.4 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation SRPRB PF09439.10 CBK22439.2 - 0.0054 16.2 0.0 1.3 8.4 0.0 2.2 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit Arf PF00025.21 CBK22439.2 - 0.007 15.8 0.0 1.3 8.5 0.0 2.3 2 0 0 2 2 2 1 ADP-ribosylation factor family Ras PF00071.22 CBK22439.2 - 0.01 15.5 0.0 0.73 9.4 0.0 2.2 2 0 0 2 2 2 1 Ras family cobW PF02492.19 CBK22439.2 - 0.011 15.4 0.2 0.11 12.1 0.1 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_22 PF13401.6 CBK22439.2 - 0.011 16.0 0.0 0.024 14.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain 6PF2K PF01591.18 CBK22439.2 - 0.014 14.7 0.0 0.031 13.6 0.0 1.4 1 0 0 1 1 1 0 6-phosphofructo-2-kinase AAA_18 PF13238.6 CBK22439.2 - 0.019 15.5 0.0 0.028 15.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain Viral_helicase1 PF01443.18 CBK22439.2 - 0.021 14.6 0.0 0.044 13.5 0.0 1.5 2 0 0 2 2 1 0 Viral (Superfamily 1) RNA helicase AAA_14 PF13173.6 CBK22439.2 - 0.022 14.8 0.0 0.056 13.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 CBK22439.2 - 0.024 15.1 0.1 0.32 11.4 0.0 2.4 3 0 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) NTPase_1 PF03266.15 CBK22439.2 - 0.032 14.2 0.1 0.12 12.2 0.1 1.9 2 0 0 2 2 2 0 NTPase AAA_33 PF13671.6 CBK22439.2 - 0.033 14.4 0.0 0.056 13.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_31 PF13614.6 CBK22439.2 - 0.033 14.1 0.1 0.13 12.1 0.1 2.0 2 1 0 2 2 2 0 AAA domain KAP_NTPase PF07693.14 CBK22439.2 - 0.042 13.1 0.0 0.058 12.6 0.0 1.2 1 0 0 1 1 1 0 KAP family P-loop domain DUF87 PF01935.17 CBK22439.2 - 0.042 13.9 0.0 0.07 13.2 0.0 1.5 1 0 0 1 1 1 0 Helicase HerA, central domain AAA_10 PF12846.7 CBK22439.2 - 0.046 12.6 0.0 0.073 12.0 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain Roc PF08477.13 CBK22439.2 - 0.052 13.8 0.0 1.3 9.2 0.0 2.4 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_19 PF13245.6 CBK22439.2 - 0.06 13.7 0.0 0.12 12.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 CBK22439.2 - 0.063 13.2 0.0 0.1 12.5 0.0 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea DUF5590 PF17881.1 CBK22439.2 - 0.071 13.2 0.1 0.16 12.1 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF5590) DUF2075 PF09848.9 CBK22439.2 - 0.087 12.1 0.0 0.12 11.6 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) PIF1 PF05970.14 CBK22439.2 - 0.11 11.6 0.0 0.18 11.0 0.0 1.2 1 0 0 1 1 1 0 PIF1-like helicase AAA_29 PF13555.6 CBK22439.2 - 0.13 12.1 0.0 0.26 11.0 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain MobB PF03205.14 CBK22439.2 - 0.14 12.0 0.0 0.24 11.3 0.0 1.3 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Thymidylate_kin PF02223.17 CBK22439.2 - 0.15 11.7 0.0 0.29 10.8 0.0 1.5 1 0 0 1 1 1 0 Thymidylate kinase KTI12 PF08433.10 CBK22439.2 - 0.16 11.4 0.0 0.24 10.8 0.0 1.2 1 0 0 1 1 1 0 Chromatin associated protein KTI12 ABC_tran PF00005.27 CBK22439.2 - 0.16 12.5 0.0 0.33 11.5 0.0 1.4 1 0 0 1 1 1 0 ABC transporter BCIP PF13862.6 CBK22440.2 - 3.9e-38 131.3 0.0 5.1e-38 130.9 0.0 1.1 1 0 0 1 1 1 1 p21-C-terminal region-binding protein Endonuc-HincII PF09226.11 CBK22440.2 - 0.0046 16.3 0.3 0.0058 16.0 0.3 1.1 1 0 0 1 1 1 1 Restriction endonuclease HincII DUF5611 PF18446.1 CBK22440.2 - 0.15 12.9 0.4 6.5 7.7 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF5611) Ribosomal_60s PF00428.19 CBK22441.2 - 2.3e-22 79.4 17.3 2.7e-22 79.2 17.3 1.0 1 0 0 1 1 1 1 60s Acidic ribosomal protein RNA_pol_3_Rpc31 PF11705.8 CBK22441.2 - 1.2 9.3 9.5 1.5 9.0 9.5 1.1 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Ribosomal_L18 PF17135.4 CBK22442.2 - 6.3e-90 299.6 0.6 7.3e-90 299.4 0.6 1.0 1 0 0 1 1 1 1 Ribosomal protein 60S L18 and 50S L18e Ribosomal_L27A PF00828.19 CBK22442.2 - 0.00091 19.9 0.9 0.0018 18.9 0.0 2.0 2 1 0 2 2 2 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A OprF PF05736.11 CBK22442.2 - 0.14 11.9 0.0 0.27 11.0 0.0 1.4 1 1 0 1 1 1 0 OprF membrane domain Ribosomal_S17e PF00833.18 CBK22443.2 - 1.5e-54 183.1 1.0 2.1e-54 182.7 1.0 1.2 1 0 0 1 1 1 1 Ribosomal S17 ParA PF10609.9 CBK22444.2 - 8.9e-75 251.3 0.0 1.2e-74 250.9 0.0 1.1 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 CBK22444.2 - 1.1e-11 44.9 0.0 1.8e-11 44.2 0.0 1.3 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 CBK22444.2 - 8e-11 42.2 0.1 4.2e-08 33.3 0.0 2.4 2 0 0 2 2 2 2 AAA domain FeS_assembly_P PF01883.19 CBK22444.2 - 6.1e-07 29.5 0.0 1.2e-06 28.5 0.0 1.6 1 0 0 1 1 1 1 Iron-sulfur cluster assembly protein MipZ PF09140.11 CBK22444.2 - 1e-06 28.2 0.0 1.6e-06 27.6 0.0 1.3 1 0 0 1 1 1 1 ATPase MipZ CBP_BcsQ PF06564.12 CBK22444.2 - 4.1e-05 23.2 0.1 0.00012 21.6 0.1 1.7 1 1 0 1 1 1 1 Cellulose biosynthesis protein BcsQ ArsA_ATPase PF02374.15 CBK22444.2 - 0.00015 21.0 3.5 0.033 13.4 0.2 3.7 3 1 1 4 4 4 1 Anion-transporting ATPase Fer4_NifH PF00142.18 CBK22444.2 - 0.00036 20.1 0.1 0.001 18.6 0.1 1.8 2 1 0 2 2 2 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family VirC1 PF07015.11 CBK22444.2 - 0.047 13.0 0.2 0.12 11.6 0.1 1.7 1 1 1 2 2 2 0 VirC1 protein FTHFS PF01268.19 CBK22444.2 - 0.16 10.2 0.0 0.23 9.6 0.0 1.2 1 0 0 1 1 1 0 Formate--tetrahydrofolate ligase Csm2_III-A PF03750.13 CBK22446.2 - 0.052 14.4 0.4 0.057 14.3 0.4 1.1 1 0 0 1 1 1 0 Csm2 Type III-A AA_synth PF06684.11 CBK22446.2 - 0.071 12.6 0.0 0.09 12.3 0.0 1.1 1 0 0 1 1 1 0 Amino acid synthesis Y_phosphatase3 PF13350.6 CBK22447.2 - 0.0001 22.4 0.0 0.00015 21.8 0.0 1.4 1 1 0 1 1 1 1 Tyrosine phosphatase family CDKN3 PF05706.12 CBK22447.2 - 0.00018 21.2 0.1 0.00031 20.5 0.1 1.4 1 0 0 1 1 1 1 Cyclin-dependent kinase inhibitor 3 (CDKN3) PTPlike_phytase PF14566.6 CBK22447.2 - 0.0023 18.1 0.0 0.0038 17.4 0.0 1.3 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase PF00102.27 CBK22447.2 - 0.0042 16.7 0.2 0.0084 15.7 0.1 1.4 1 1 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.20 CBK22447.2 - 0.025 14.4 0.1 0.057 13.2 0.1 1.6 1 1 1 2 2 2 0 Dual specificity phosphatase, catalytic domain Y_phosphatase2 PF03162.13 CBK22447.2 - 0.13 11.9 0.3 0.31 10.6 0.4 1.7 1 1 0 1 1 1 0 Tyrosine phosphatase family PTEN_C2 PF10409.9 CBK22448.2 - 2.5e-05 24.1 0.0 6e-05 22.8 0.0 1.6 1 0 0 1 1 1 1 C2 domain of PTEN tumour-suppressor protein DUF3446 PF11928.8 CBK22448.2 - 0.0019 18.5 14.6 0.0019 18.5 14.6 2.4 2 0 0 2 2 2 1 Early growth response N-terminal domain AF-4 PF05110.13 CBK22448.2 - 0.23 9.5 22.1 0.32 9.1 22.1 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Ribosomal_L29 PF00831.23 CBK22449.2 - 1.4e-12 47.4 0.4 1.4e-12 47.4 0.4 2.3 1 1 0 2 2 2 1 Ribosomal L29 protein Rogdi_lz PF10259.9 CBK22449.2 - 0.00038 20.0 0.1 0.00044 19.8 0.1 1.0 1 0 0 1 1 1 1 Rogdi leucine zipper containing protein CHASE3 PF05227.13 CBK22449.2 - 0.0045 16.9 5.6 0.0055 16.6 5.6 1.1 1 0 0 1 1 1 1 CHASE3 domain Ribosomal_S9 PF00380.19 CBK22449.2 - 0.017 15.7 7.1 0.025 15.1 7.1 1.3 1 1 0 1 1 1 0 Ribosomal protein S9/S16 DUF382 PF04037.13 CBK22449.2 - 0.021 15.0 1.6 0.028 14.6 1.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF382) RhaA PF06134.11 CBK22449.2 - 0.13 11.4 0.3 0.2 10.7 0.2 1.4 1 1 1 2 2 2 0 L-rhamnose isomerase (RhaA) PP2C PF00481.21 CBK22450.2 - 4.8e-35 121.4 0.0 6.7e-35 121.0 0.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 CBK22450.2 - 0.00012 21.8 0.1 0.00043 20.0 0.1 1.9 1 1 0 1 1 1 1 Protein phosphatase 2C PEPCK_ATP PF01293.20 CBK22451.2 - 0.00053 18.8 0.0 0.00082 18.2 0.0 1.2 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase Sugar_tr PF00083.24 CBK22452.2 - 0.00017 20.6 8.1 0.0002 20.3 8.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter 2-Hacid_dh_C PF02826.19 CBK22453.2 - 7.9e-63 211.0 0.0 1e-62 210.6 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 CBK22453.2 - 8.6e-27 93.4 0.0 1e-26 93.1 0.0 1.0 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain AdoHcyase_NAD PF00670.21 CBK22453.2 - 1.1e-05 25.5 0.0 2e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain NAD_binding_2 PF03446.15 CBK22453.2 - 0.0034 17.6 0.0 0.0083 16.3 0.0 1.6 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase IlvN PF07991.12 CBK22453.2 - 0.014 15.0 0.0 0.022 14.3 0.0 1.3 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain NmrA PF05368.13 CBK22453.2 - 0.065 12.8 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 NmrA-like family Hydrolase_6 PF13344.6 CBK22454.2 - 3.5e-30 104.1 0.0 5.6e-30 103.4 0.0 1.3 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 CBK22454.2 - 7.2e-16 58.0 0.0 3.4e-15 55.8 0.0 2.0 2 0 0 2 2 2 1 HAD-hyrolase-like Hydrolase PF00702.26 CBK22454.2 - 4.5e-09 36.9 0.0 6.7e-09 36.3 0.0 1.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 CBK22454.2 - 1.5e-06 28.4 0.6 0.0094 16.1 0.1 2.6 2 1 1 3 3 3 2 Haloacid dehalogenase-like hydrolase PGP_phosphatase PF09419.10 CBK22454.2 - 0.00095 18.8 0.0 0.0021 17.7 0.0 1.6 1 0 0 1 1 1 1 Mitochondrial PGP phosphatase Acid_phosphat_B PF03767.14 CBK22454.2 - 0.0013 18.4 0.0 0.0019 17.8 0.0 1.2 1 0 0 1 1 1 1 HAD superfamily, subfamily IIIB (Acid phosphatase) MRP-L27 PF09809.9 CBK22456.2 - 1.5e-18 66.7 0.2 1.7e-18 66.5 0.2 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L27 F-actin_cap_A PF01267.17 CBK22457.2 - 1.5e-32 113.1 0.0 1.8e-32 112.9 0.0 1.0 1 0 0 1 1 1 1 F-actin capping protein alpha subunit Tim17 PF02466.19 CBK22458.2 - 8.8e-18 64.7 2.7 1.1e-17 64.4 2.7 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family DnaJ_CXXCXGXG PF00684.19 CBK22459.2 - 1e-05 25.8 5.9 1e-05 25.8 5.9 2.9 3 0 0 3 3 3 1 DnaJ central domain zf-Di19 PF05605.12 CBK22459.2 - 0.0032 17.7 8.9 0.49 10.7 3.1 3.4 3 1 0 3 3 3 2 Drought induced 19 protein (Di19), zinc-binding Anti-TRAP PF15777.5 CBK22459.2 - 0.0036 17.2 8.9 0.0087 16.0 2.1 3.6 2 1 2 4 4 4 2 Tryptophan RNA-binding attenuator protein inhibitory protein zf-H2C2_2 PF13465.6 CBK22459.2 - 0.71 10.4 0.1 0.71 10.4 0.1 4.5 5 0 0 5 5 5 0 Zinc-finger double domain MRP-S26 PF14943.6 CBK22460.2 - 0.0014 18.6 3.3 0.0014 18.6 3.3 2.9 3 0 0 3 3 3 1 Mitochondrial ribosome subunit S26 TSC22 PF01166.18 CBK22460.2 - 0.34 11.2 14.3 0.74 10.2 0.2 3.9 3 1 1 4 4 4 0 TSC-22/dip/bun family Apolipoprotein PF01442.18 CBK22460.2 - 1.2 9.0 21.7 1.2 9.0 8.3 2.6 2 1 0 2 2 2 0 Apolipoprotein A1/A4/E domain Filament PF00038.21 CBK22460.2 - 1.3 8.5 29.9 0.031 13.9 7.0 3.6 2 2 0 2 2 2 0 Intermediate filament protein DUF2935 PF11155.8 CBK22460.2 - 2.4 8.5 7.1 2.5 8.5 2.3 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF2935) WAK_assoc PF14380.6 CBK22460.2 - 3.5 8.4 9.7 0.2 12.4 0.4 2.8 3 0 0 3 3 3 0 Wall-associated receptor kinase C-terminal Tmemb_cc2 PF10267.9 CBK22460.2 - 8 5.5 31.6 0.057 12.6 9.5 3.0 2 1 1 3 3 3 0 Predicted transmembrane and coiled-coil 2 protein DUF1664 PF07889.12 CBK22460.2 - 8.5 6.4 15.6 2.8 8.0 1.8 3.9 3 1 0 4 4 4 0 Protein of unknown function (DUF1664) DNA_pol_B_2 PF03175.13 CBK22462.2 - 2.9e-17 62.7 6.4 2.9e-17 62.7 6.4 1.6 2 0 0 2 2 2 1 DNA polymerase type B, organellar and viral Lyase_8 PF02278.18 CBK22462.2 - 0.14 11.6 0.3 0.54 9.7 0.1 1.9 2 0 0 2 2 2 0 Polysaccharide lyase family 8, super-sandwich domain POR_N PF01855.19 CBK22463.2 - 4.8e-46 157.4 0.0 8.4e-46 156.6 0.0 1.4 1 0 0 1 1 1 1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg POR PF01558.18 CBK22463.2 - 1.5e-28 100.0 0.4 3.2e-28 99.0 0.4 1.6 1 0 0 1 1 1 1 Pyruvate ferredoxin/flavodoxin oxidoreductase PFOR_II PF17147.4 CBK22463.2 - 6.5e-15 55.3 0.1 2.1e-14 53.6 0.1 2.0 1 0 0 1 1 1 1 Pyruvate:ferredoxin oxidoreductase core domain II Fer4_16 PF13484.6 CBK22463.2 - 1.2e-10 42.1 15.2 3.7e-08 34.2 8.7 2.8 1 1 1 2 2 2 2 4Fe-4S double cluster binding domain Fer4_7 PF12838.7 CBK22463.2 - 1.6e-09 38.2 6.7 5.9e-09 36.4 6.7 2.1 1 0 0 1 1 1 1 4Fe-4S dicluster domain EKR PF10371.9 CBK22463.2 - 5.9e-09 35.6 0.0 1.9e-08 33.9 0.0 1.9 1 0 0 1 1 1 1 Domain of unknown function TPP_enzyme_C PF02775.21 CBK22463.2 - 2.1e-08 34.1 0.2 5.8e-08 32.7 0.2 1.8 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Fer4_9 PF13187.6 CBK22463.2 - 3.5e-08 33.5 6.0 0.0022 18.1 1.0 2.7 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4 PF00037.27 CBK22463.2 - 5e-08 32.4 18.7 1.8e-05 24.3 1.3 3.2 3 0 0 3 3 3 2 4Fe-4S binding domain Fer4_21 PF14697.6 CBK22463.2 - 9.7e-08 32.0 7.6 0.0017 18.5 1.0 2.9 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_10 PF13237.6 CBK22463.2 - 1.8e-07 31.2 7.8 0.0032 17.5 1.0 2.8 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_6 PF12837.7 CBK22463.2 - 2.4e-06 27.4 19.3 2.3e-05 24.3 2.7 3.1 3 0 0 3 3 3 2 4Fe-4S binding domain Fer4_8 PF13183.6 CBK22463.2 - 3e-05 24.4 6.4 0.00015 22.1 6.5 2.3 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_18 PF13746.6 CBK22463.2 - 0.00084 19.5 3.6 0.42 10.8 0.4 2.8 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_2 PF12797.7 CBK22463.2 - 0.00095 19.1 22.7 0.02 15.0 4.3 3.2 3 0 0 3 3 3 2 4Fe-4S binding domain Fer4_17 PF13534.6 CBK22463.2 - 0.0011 19.4 12.2 0.011 16.2 11.1 2.8 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_13 PF13370.6 CBK22463.2 - 0.0012 19.3 8.5 0.11 13.0 1.3 3.3 3 0 0 3 3 3 2 4Fe-4S single cluster domain of Ferredoxin I Fer4_4 PF12800.7 CBK22463.2 - 0.0052 17.2 17.8 0.0079 16.6 1.4 3.1 3 0 0 3 3 2 2 4Fe-4S binding domain Transketolase_C PF02780.20 CBK22463.2 - 0.088 12.7 0.0 0.32 10.9 0.0 2.0 1 0 0 1 1 1 0 Transketolase, C-terminal domain BrkDBD PF09607.10 CBK22463.2 - 0.14 12.0 0.3 0.96 9.3 0.1 2.3 2 0 0 2 2 2 0 Brinker DNA-binding domain Fer4_15 PF13459.6 CBK22463.2 - 1.2 9.9 9.5 8.6 7.2 1.4 2.9 2 0 0 2 2 2 0 4Fe-4S single cluster domain Fer4_3 PF12798.7 CBK22463.2 - 2.5 9.3 19.4 7.9 7.7 5.7 2.9 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_22 PF17179.4 CBK22463.2 - 8.8 7.3 12.4 13 6.7 0.2 3.5 2 1 2 4 4 4 0 4Fe-4S dicluster domain Brix PF04427.18 CBK22464.2 - 4.4e-37 128.1 0.4 4.4e-37 128.1 0.4 1.5 2 0 0 2 2 2 1 Brix domain Fe-ADH PF00465.19 CBK22465.2 - 4e-47 160.8 0.0 4.4e-47 160.6 0.0 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase DASH_Dad3 PF08656.10 CBK22466.2 - 5.6e-05 23.1 0.6 7.1e-05 22.8 0.6 1.2 1 0 0 1 1 1 1 DASH complex subunit Dad3 CdvA PF18822.1 CBK22466.2 - 0.0031 17.3 0.3 0.0041 17.0 0.3 1.3 1 0 0 1 1 1 1 CdvA-like coiled-coil domain Prominin PF05478.11 CBK22466.2 - 0.0032 15.5 0.8 0.0034 15.4 0.8 1.1 1 0 0 1 1 1 1 Prominin DUF4763 PF15960.5 CBK22466.2 - 0.015 14.6 1.0 0.017 14.5 0.9 1.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4763) SlyX PF04102.12 CBK22466.2 - 0.016 15.8 0.5 0.021 15.5 0.4 1.4 1 1 0 1 1 1 0 SlyX DASH_Hsk3 PF08227.11 CBK22466.2 - 0.019 15.4 1.5 0.39 11.1 0.3 2.3 1 1 1 2 2 2 0 DASH complex subunit Hsk3 like Zot PF05707.12 CBK22466.2 - 0.047 13.3 0.0 0.052 13.2 0.0 1.1 1 0 0 1 1 1 0 Zonular occludens toxin (Zot) AI-2E_transport PF01594.16 CBK22466.2 - 0.063 12.4 0.6 0.073 12.2 0.6 1.0 1 0 0 1 1 1 0 AI-2E family transporter DUF1664 PF07889.12 CBK22466.2 - 0.083 12.9 0.4 0.38 10.8 0.2 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Fzo_mitofusin PF04799.13 CBK22466.2 - 0.16 11.5 2.0 0.4 10.2 2.0 1.7 1 1 0 1 1 1 0 fzo-like conserved region MORN PF02493.20 CBK22467.2 - 1.9e-09 36.8 10.9 3.1e-06 26.7 1.0 3.5 3 0 0 3 3 3 2 MORN repeat MORN_2 PF07661.13 CBK22468.2 - 2.2e-08 33.4 20.3 0.22 11.9 0.9 7.1 6 0 0 6 6 6 4 MORN repeat variant MORN PF02493.20 CBK22468.2 - 1.6e-05 24.5 33.2 0.00029 20.5 0.6 9.0 10 0 0 10 10 10 4 MORN repeat DUF3048_C PF17479.2 CBK22468.2 - 0.0013 19.1 1.4 0.11 12.9 0.0 3.4 4 0 0 4 4 4 1 Protein of unknown function (DUF3048) C-terminal domain Aminotran_5 PF00266.19 CBK22469.2 - 1.6e-34 119.4 0.0 2.4e-34 118.9 0.0 1.3 1 1 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 CBK22469.2 - 0.0045 16.2 0.0 0.025 13.7 0.0 2.0 2 0 0 2 2 2 1 Aminotransferase class I and II DUF1664 PF07889.12 CBK22470.2 - 7.4e-12 45.4 77.4 0.0024 17.9 3.2 8.8 2 1 6 8 8 8 6 Protein of unknown function (DUF1664) Spc7 PF08317.11 CBK22470.2 - 3e-08 32.9 104.1 0.00044 19.2 13.1 6.1 1 1 5 6 6 6 5 Spc7 kinetochore protein Baculo_PEP_C PF04513.12 CBK22470.2 - 1.6e-07 31.4 69.5 0.023 14.8 0.2 7.0 2 1 2 6 6 6 4 Baculovirus polyhedron envelope protein, PEP, C terminus WEMBL PF05701.11 CBK22470.2 - 9.5e-07 27.9 28.8 9.5e-07 27.9 28.8 5.2 1 1 4 5 5 4 2 Weak chloroplast movement under blue light Laminin_II PF06009.12 CBK22470.2 - 1.6e-06 28.1 96.7 0.00022 21.2 3.9 9.5 1 1 9 10 10 10 3 Laminin Domain II Syntaxin PF00804.25 CBK22470.2 - 1.4e-05 24.9 79.8 0.06 13.0 6.5 7.5 3 3 3 7 7 7 5 Syntaxin CENP-F_leu_zip PF10473.9 CBK22470.2 - 0.00021 21.3 99.4 0.21 11.6 6.9 8.9 1 1 6 8 8 8 3 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Tropomyosin PF00261.20 CBK22470.2 - 0.00042 19.8 26.7 0.00042 19.8 26.7 5.9 2 2 2 4 4 4 1 Tropomyosin AAA_13 PF13166.6 CBK22470.2 - 0.00049 18.9 18.0 0.00049 18.9 18.0 4.2 1 1 3 4 4 4 2 AAA domain DUF948 PF06103.11 CBK22470.2 - 0.00067 19.9 73.9 0.67 10.2 0.2 10.8 2 2 9 11 11 11 3 Bacterial protein of unknown function (DUF948) EzrA PF06160.12 CBK22470.2 - 0.00097 17.4 75.7 0.0047 15.2 35.6 4.9 1 1 3 4 4 4 2 Septation ring formation regulator, EzrA DUF3584 PF12128.8 CBK22470.2 - 0.0016 16.1 97.0 0.0029 15.2 32.1 3.5 1 1 2 3 3 3 2 Protein of unknown function (DUF3584) TPR_MLP1_2 PF07926.12 CBK22470.2 - 0.0016 18.5 116.7 0.071 13.2 3.5 8.4 3 2 5 8 8 8 3 TPR/MLP1/MLP2-like protein DUF3450 PF11932.8 CBK22470.2 - 0.0027 17.0 6.7 0.0027 17.0 6.7 7.6 2 2 5 8 8 8 1 Protein of unknown function (DUF3450) BLOC1_2 PF10046.9 CBK22470.2 - 0.0033 17.7 82.5 0.021 15.1 6.0 11.0 2 2 8 11 11 11 3 Biogenesis of lysosome-related organelles complex-1 subunit 2 TMF_TATA_bd PF12325.8 CBK22470.2 - 0.0042 17.3 4.4 0.0042 17.3 4.4 10.0 1 1 7 8 8 6 1 TATA element modulatory factor 1 TATA binding NPV_P10 PF05531.12 CBK22470.2 - 0.0051 17.3 67.0 1.4 9.5 0.4 11.1 5 2 4 10 10 10 1 Nucleopolyhedrovirus P10 protein DUF745 PF05335.13 CBK22470.2 - 0.0086 15.8 115.6 0.022 14.5 20.6 8.2 1 1 8 9 9 9 1 Protein of unknown function (DUF745) Fez1 PF06818.15 CBK22470.2 - 0.0096 16.4 90.2 0.98 9.8 19.7 6.3 1 1 5 6 6 6 3 Fez1 SesA PF17107.5 CBK22470.2 - 0.014 15.6 8.3 0.014 15.6 8.3 7.1 1 1 7 8 8 8 0 N-terminal domain on NACHT_NTPase and P-loop NTPases Golgin_A5 PF09787.9 CBK22470.2 - 0.015 14.7 96.8 0.79 9.1 9.9 6.0 1 1 4 5 5 5 0 Golgin subfamily A member 5 Fib_alpha PF08702.10 CBK22470.2 - 0.028 14.6 75.7 1.2 9.3 2.3 8.5 1 1 9 11 11 11 0 Fibrinogen alpha/beta chain family Phospholip_A2_1 PF00068.19 CBK22470.2 - 0.041 14.4 1.0 0.15 12.5 1.0 2.0 1 0 0 1 1 1 0 Phospholipase A2 MscS_porin PF12795.7 CBK22470.2 - 0.058 12.9 108.0 0.32 10.5 17.2 6.0 1 1 3 5 5 5 0 Mechanosensitive ion channel porin domain Prominin PF05478.11 CBK22470.2 - 0.077 10.9 69.0 0.13 10.2 13.5 4.2 1 1 3 4 4 4 0 Prominin IL32 PF15225.6 CBK22470.2 - 0.12 12.8 2.8 12 6.4 0.0 4.2 4 1 0 4 4 3 0 Interleukin 32 GAS PF13851.6 CBK22470.2 - 0.12 11.7 84.2 0.13 11.6 10.5 6.2 1 1 3 5 5 5 0 Growth-arrest specific micro-tubule binding Filament PF00038.21 CBK22470.2 - 0.15 11.6 99.2 0.29 10.7 9.0 6.2 1 1 5 6 6 6 0 Intermediate filament protein AIP3 PF03915.13 CBK22470.2 - 0.41 9.7 88.5 0.013 14.6 15.0 4.6 1 1 3 4 4 4 0 Actin interacting protein 3 CENP-H PF05837.12 CBK22470.2 - 0.56 10.6 91.3 0.22 11.9 7.1 8.3 2 1 6 8 8 8 0 Centromere protein H (CENP-H) Laminin_I PF06008.14 CBK22470.2 - 0.6 9.8 97.2 1.7 8.3 3.8 6.3 1 1 2 4 4 4 0 Laminin Domain I DUF812 PF05667.11 CBK22470.2 - 0.6 8.9 100.3 0.42 9.4 22.6 5.2 1 1 4 5 5 5 0 Protein of unknown function (DUF812) Mod_r PF07200.13 CBK22470.2 - 0.71 10.0 89.4 0.056 13.6 5.5 7.4 1 1 5 7 7 7 0 Modifier of rudimentary (Mod(r)) protein RPW8 PF05659.11 CBK22470.2 - 0.89 9.2 39.6 2.8 7.6 0.3 8.9 1 1 9 11 11 11 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 TACC_C PF05010.14 CBK22470.2 - 0.89 9.3 77.1 0.15 11.8 17.2 6.5 1 1 6 8 8 8 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal IFT57 PF10498.9 CBK22470.2 - 0.98 8.3 79.3 0.26 10.2 2.8 6.0 1 1 4 6 6 6 0 Intra-flagellar transport protein 57 B2 PF11473.8 CBK22470.2 - 1.8 8.4 9.5 0.52 10.2 2.0 3.7 3 0 0 3 3 3 0 RNA binding protein B2 FlaC_arch PF05377.11 CBK22470.2 - 3.5 8.1 74.5 1.4 9.4 0.2 13.8 4 3 8 13 13 12 0 Flagella accessory protein C (FlaC) LPP PF04728.13 CBK22470.2 - 3.7 8.0 110.0 1 9.8 1.8 15.2 8 5 5 14 14 14 0 Lipoprotein leucine-zipper CALCOCO1 PF07888.11 CBK22470.2 - 3.9 6.2 91.4 0.76 8.6 34.9 4.1 1 1 2 4 4 4 0 Calcium binding and coiled-coil domain (CALCOCO1) like TolA_bind_tri PF16331.5 CBK22470.2 - 5.6 7.1 73.9 0.084 13.0 4.5 11.4 4 4 6 10 10 9 0 TolA binding protein trimerisation Sec34 PF04136.15 CBK22470.2 - 6.6 6.6 66.2 3.9 7.3 2.6 8.8 2 2 4 10 10 10 0 Sec34-like family Cyclin_C PF02984.19 CBK22471.2 - 0.00024 21.2 0.4 0.00078 19.5 0.2 1.9 2 0 0 2 2 2 1 Cyclin, C-terminal domain Pkinase PF00069.25 CBK22472.2 - 4.5e-56 190.1 0.0 5.5e-56 189.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBK22472.2 - 5.7e-18 65.1 0.0 9e-18 64.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 CBK22472.2 - 8.3e-07 29.2 0.0 9.2e-06 25.7 0.1 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 CBK22472.2 - 0.0048 16.5 0.3 0.028 14.0 0.1 2.1 2 0 0 2 2 2 1 Choline/ethanolamine kinase RIO1 PF01163.22 CBK22472.2 - 0.038 13.6 0.2 1 8.9 0.0 2.4 2 0 0 2 2 2 0 RIO1 family Pkinase_fungal PF17667.1 CBK22472.2 - 0.039 12.7 0.0 0.056 12.2 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Kdo PF06293.14 CBK22472.2 - 0.047 13.0 0.0 0.11 11.8 0.0 1.6 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 CBK22472.2 - 0.048 13.0 0.1 0.21 10.8 0.0 2.0 3 0 0 3 3 3 0 Kinase-like PRP4 PF08799.11 CBK22473.2 - 1.1e-13 50.5 0.2 1.6e-13 50.0 0.2 1.3 1 0 0 1 1 1 1 pre-mRNA processing factor 4 (PRP4) like SNAD1 PF18744.1 CBK22473.2 - 0.024 14.5 0.0 0.03 14.2 0.0 1.1 1 0 0 1 1 1 0 Secreted Novel AID/APOBEC-like Deaminase 1 Haemadin PF09065.10 CBK22473.2 - 0.14 11.9 0.3 0.27 11.1 0.3 1.4 1 0 0 1 1 1 0 Haemadin WD40 PF00400.32 CBK22474.2 - 3e-30 103.8 8.5 2.5e-06 28.1 0.2 5.5 5 0 0 5 5 5 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBK22474.2 - 4.3e-10 39.8 0.0 0.31 11.4 0.0 4.2 1 1 3 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 CBK22474.2 - 0.00021 20.1 3.4 1.7 7.2 0.1 3.5 2 2 1 3 3 3 3 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 CBK22474.2 - 0.0039 16.2 0.0 1.2 8.0 0.0 3.0 2 1 2 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein CSD PF00313.22 CBK22475.2 - 3.7e-26 90.7 0.1 4.8e-26 90.4 0.1 1.2 1 0 0 1 1 1 1 'Cold-shock' DNA-binding domain OB_RNB PF08206.11 CBK22475.2 - 0.00026 20.6 0.1 0.00049 19.7 0.0 1.4 1 1 0 1 1 1 1 Ribonuclease B OB domain Rho_RNA_bind PF07497.12 CBK22475.2 - 0.004 17.0 0.0 0.0057 16.5 0.0 1.3 1 0 0 1 1 1 1 Rho termination factor, RNA-binding domain MORN PF02493.20 CBK22476.2 - 3.3e-09 36.1 16.5 0.00071 19.3 0.3 5.8 5 0 0 5 5 5 3 MORN repeat LRR_8 PF13855.6 CBK22476.2 - 0.0025 17.5 3.4 0.14 12.0 0.2 3.6 4 0 0 4 4 4 1 Leucine rich repeat Pox_I5 PF04713.12 CBK22476.2 - 0.096 12.7 4.9 0.22 11.6 2.6 2.2 2 0 0 2 2 2 0 Poxvirus protein I5 MORN_2 PF07661.13 CBK22476.2 - 1.2 9.6 18.0 1.1 9.8 0.7 5.9 6 0 0 6 6 6 0 MORN repeat variant DUF1295 PF06966.12 CBK22477.2 - 3.4e-10 39.9 1.6 4.7e-10 39.4 1.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) Steroid_dh PF02544.16 CBK22477.2 - 1.1e-08 35.2 2.8 1.5e-08 34.8 2.8 1.2 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase PEMT PF04191.13 CBK22477.2 - 1e-06 29.1 2.9 1.7e-06 28.3 2.5 1.7 1 1 0 1 1 1 1 Phospholipid methyltransferase ICMT PF04140.14 CBK22477.2 - 7.1e-06 26.4 1.4 1.6e-05 25.2 1.4 1.7 1 1 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family ERG4_ERG24 PF01222.17 CBK22477.2 - 7e-05 21.8 2.8 9.3e-05 21.4 2.7 1.4 1 1 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family 2TM PF13239.6 CBK22477.2 - 0.42 11.0 7.2 2 8.7 7.2 2.1 1 1 0 1 1 1 0 2TM domain Dynamin_N PF00350.23 CBK22478.2 - 2.4e-51 174.1 0.0 3.4e-51 173.6 0.0 1.2 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.20 CBK22478.2 - 1.1e-26 93.7 0.1 1.5e-26 93.2 0.1 1.2 1 0 0 1 1 1 1 Dynamin central region MMR_HSR1 PF01926.23 CBK22478.2 - 3.2e-05 24.0 0.0 8e-05 22.7 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 CBK22478.2 - 0.042 13.4 0.2 9.8 5.7 0.0 2.2 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_28 PF13521.6 CBK22478.2 - 0.14 12.4 0.0 0.26 11.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain GED PF02212.18 CBK22479.2 - 1.5e-21 76.3 4.0 3e-21 75.4 4.0 1.5 1 0 0 1 1 1 1 Dynamin GTPase effector domain PH PF00169.29 CBK22479.2 - 2.6e-05 24.7 0.1 4.1e-05 24.0 0.1 1.3 1 0 0 1 1 1 1 PH domain TFIIF_beta PF02270.15 CBK22479.2 - 0.0086 16.2 0.2 0.81 9.9 0.0 2.5 2 0 0 2 2 2 1 TFIIF, beta subunit HTH domain REV PF00424.18 CBK22479.2 - 0.039 14.0 0.1 0.092 12.8 0.1 1.6 1 0 0 1 1 1 0 REV protein (anti-repression trans-activator protein) PH_8 PF15409.6 CBK22479.2 - 0.055 13.7 0.2 0.17 12.2 0.2 1.9 1 0 0 1 1 1 0 Pleckstrin homology domain DUF2018 PF09442.10 CBK22479.2 - 0.1 13.6 3.4 0.23 12.5 0.5 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF2018) DUF3510 PF12022.8 CBK22479.2 - 0.15 12.5 2.0 1.4 9.3 0.2 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF3510) Pkinase PF00069.25 CBK22480.2 - 1.4e-16 60.7 0.0 1.6e-16 60.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBK22480.2 - 1.8e-09 37.3 0.0 2.3e-09 36.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase DNA_pol_B_2 PF03175.13 CBK22481.2 - 9.8e-18 64.3 12.3 3.4e-15 55.9 8.2 2.3 2 0 0 2 2 2 2 DNA polymerase type B, organellar and viral He_PIG PF05345.12 CBK22482.2 - 4.1e-15 55.7 40.4 1.3e-05 25.3 5.9 5.3 4 1 0 4 4 4 3 Putative Ig domain BetaGal_dom4_5 PF13364.6 CBK22482.2 - 2.2e-06 28.2 1.4 0.00016 22.2 0.3 2.8 2 0 0 2 2 2 1 Beta-galactosidase jelly roll domain I-set PF07679.16 CBK22482.2 - 0.00027 21.0 3.1 2.6 8.2 0.0 5.1 5 0 0 5 5 5 1 Immunoglobulin I-set domain F5_F8_type_C PF00754.25 CBK22482.2 - 0.0067 16.5 17.9 0.16 12.1 0.1 5.5 5 1 1 6 6 5 3 F5/8 type C domain Shisa PF13908.6 CBK22482.2 - 0.024 14.9 1.7 0.072 13.3 1.7 1.8 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator Orf78 PF06024.12 CBK22482.2 - 0.033 14.5 1.1 0.068 13.5 1.1 1.4 1 0 0 1 1 1 0 Orf78 (ac78) EphA2_TM PF14575.6 CBK22482.2 - 0.041 14.8 1.2 0.078 13.9 1.2 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain OAD_gamma PF04277.13 CBK22482.2 - 0.055 14.1 5.5 0.11 13.1 5.5 1.4 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain Baculo_11_kDa PF06143.11 CBK22482.2 - 0.066 12.8 3.2 0.13 11.8 3.2 1.4 1 0 0 1 1 1 0 Baculovirus 11 kDa family DUF5305 PF17231.2 CBK22482.2 - 0.11 11.9 2.4 0.27 10.6 2.4 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5305) OSTbeta PF15048.6 CBK22482.2 - 0.22 11.6 0.5 0.45 10.7 0.5 1.4 1 0 0 1 1 1 0 Organic solute transporter subunit beta protein DUF5385 PF17359.2 CBK22482.2 - 1 8.9 2.7 1.6 8.2 2.7 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5385) RIFIN PF02009.16 CBK22482.2 - 1.1 9.1 3.3 2.5 7.9 3.3 1.5 1 0 0 1 1 1 0 Rifin TMEM154 PF15102.6 CBK22482.2 - 1.3 8.9 8.6 0.049 13.5 2.0 2.0 2 0 0 2 2 2 0 TMEM154 protein family ASFV_J13L PF05568.11 CBK22482.2 - 7.8 6.2 9.8 2.4 7.9 5.7 2.3 2 0 0 2 2 1 0 African swine fever virus J13L protein ECSCR PF15820.5 CBK22482.2 - 8.8 6.2 8.2 1.2 9.0 3.4 2.0 2 0 0 2 2 2 0 Endothelial cell-specific chemotaxis regulator Fe_hyd_lg_C PF02906.14 CBK22483.2 - 1.9e-49 168.6 0.0 1.4e-44 152.6 0.0 2.4 2 0 0 2 2 2 2 Iron only hydrogenase large subunit, C-terminal domain DUF2691 PF10903.8 CBK22483.2 - 0.18 11.6 0.0 0.33 10.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2691) MFS_1 PF07690.16 CBK22484.2 - 4e-29 101.7 51.1 1.1e-25 90.4 30.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Guanylate_kin PF00625.21 CBK22485.2 - 1e-53 181.7 0.3 1.4e-53 181.3 0.3 1.1 1 0 0 1 1 1 1 Guanylate kinase AAA_33 PF13671.6 CBK22485.2 - 1.2e-07 32.0 0.0 8e-07 29.3 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 CBK22485.2 - 4e-05 23.9 0.0 9.9e-05 22.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 CBK22485.2 - 4.2e-05 24.1 1.0 0.00073 20.1 1.0 2.4 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 CBK22485.2 - 0.0001 22.7 0.0 0.00021 21.7 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA PF00004.29 CBK22485.2 - 0.00037 20.9 0.4 0.0013 19.1 0.4 1.9 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RsgA_GTPase PF03193.16 CBK22485.2 - 0.00046 20.1 0.1 0.0014 18.6 0.0 1.8 2 0 0 2 2 2 1 RsgA GTPase NTPase_1 PF03266.15 CBK22485.2 - 0.00056 19.9 0.3 0.0011 18.9 0.2 1.7 1 1 0 1 1 1 1 NTPase ABC_tran PF00005.27 CBK22485.2 - 0.0009 19.8 0.1 0.0016 19.0 0.1 1.6 1 1 0 1 1 1 1 ABC transporter AAA_7 PF12775.7 CBK22485.2 - 0.00099 18.7 0.0 0.0027 17.3 0.0 1.7 1 1 0 1 1 1 1 P-loop containing dynein motor region Septin PF00735.18 CBK22485.2 - 0.0011 18.3 0.2 0.0024 17.2 0.0 1.7 2 0 0 2 2 2 1 Septin RNA_helicase PF00910.22 CBK22485.2 - 0.0011 19.3 0.1 0.0065 16.8 0.0 2.1 2 0 0 2 2 2 1 RNA helicase dNK PF01712.19 CBK22485.2 - 0.0018 18.2 0.4 1.3 8.9 0.2 2.3 2 0 0 2 2 2 2 Deoxynucleoside kinase MMR_HSR1 PF01926.23 CBK22485.2 - 0.0019 18.3 0.7 0.0047 17.0 0.7 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_24 PF13479.6 CBK22485.2 - 0.0034 17.1 0.2 0.0091 15.7 0.1 1.7 2 1 0 2 2 2 1 AAA domain Roc PF08477.13 CBK22485.2 - 0.0039 17.4 0.0 0.011 16.0 0.0 1.8 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase DUF815 PF05673.13 CBK22485.2 - 0.0041 16.3 0.0 0.007 15.5 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) Thymidylate_kin PF02223.17 CBK22485.2 - 0.0056 16.4 1.1 2.6 7.7 0.0 2.2 2 0 0 2 2 2 2 Thymidylate kinase AAA_17 PF13207.6 CBK22485.2 - 0.0058 17.1 0.1 0.25 11.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain PTS_IIB PF02302.17 CBK22485.2 - 0.0064 17.2 0.0 0.62 10.8 0.0 2.5 1 1 1 2 2 2 1 PTS system, Lactose/Cellobiose specific IIB subunit NACHT PF05729.12 CBK22485.2 - 0.01 15.8 0.0 0.029 14.3 0.0 1.7 2 0 0 2 2 2 0 NACHT domain ATP_bind_1 PF03029.17 CBK22485.2 - 0.011 15.5 0.4 0.11 12.2 0.0 2.1 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_14 PF13173.6 CBK22485.2 - 0.013 15.6 0.6 0.04 14.0 0.1 2.1 1 1 1 2 2 2 0 AAA domain SRP54 PF00448.22 CBK22485.2 - 0.016 14.9 0.0 0.028 14.1 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain Rad17 PF03215.15 CBK22485.2 - 0.017 15.1 0.9 0.023 14.6 0.1 1.6 2 0 0 2 2 2 0 Rad17 P-loop domain ATPase_2 PF01637.18 CBK22485.2 - 0.02 14.8 1.3 0.072 13.0 1.3 1.9 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_2 PF07724.14 CBK22485.2 - 0.026 14.6 0.2 0.099 12.8 0.2 2.0 1 1 0 1 1 1 0 AAA domain (Cdc48 subfamily) cobW PF02492.19 CBK22485.2 - 0.03 13.9 0.0 0.058 13.0 0.0 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain MobB PF03205.14 CBK22485.2 - 0.037 13.9 0.0 0.094 12.6 0.0 1.6 2 0 0 2 2 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_29 PF13555.6 CBK22485.2 - 0.037 13.8 0.2 0.1 12.4 0.0 1.8 2 0 0 2 2 2 0 P-loop containing region of AAA domain NB-ARC PF00931.22 CBK22485.2 - 0.059 12.6 0.0 0.13 11.4 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain G-alpha PF00503.20 CBK22485.2 - 0.071 12.3 2.7 0.28 10.3 2.7 1.8 1 1 0 1 1 1 0 G-protein alpha subunit AAA_28 PF13521.6 CBK22485.2 - 0.078 13.2 0.0 0.21 11.8 0.0 1.7 2 0 0 2 2 2 0 AAA domain TniB PF05621.11 CBK22485.2 - 0.08 12.3 0.0 0.15 11.5 0.0 1.4 1 0 0 1 1 1 0 Bacterial TniB protein CbiA PF01656.23 CBK22485.2 - 0.086 12.9 0.8 3.8 7.6 0.0 2.4 2 1 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_5 PF07728.14 CBK22485.2 - 0.12 12.4 0.1 0.33 10.9 0.0 1.7 2 0 0 2 2 1 0 AAA domain (dynein-related subfamily) Arf PF00025.21 CBK22485.2 - 0.23 10.9 1.2 9.5 5.6 0.0 3.1 2 2 2 4 4 4 0 ADP-ribosylation factor family PH PF00169.29 CBK22486.2 - 3.5e-05 24.3 0.0 4.3e-05 24.0 0.0 1.1 1 0 0 1 1 1 1 PH domain MscS_TM PF12794.7 CBK22487.2 - 0.078 11.8 2.6 0.11 11.3 2.6 1.2 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 DUF4763 PF15960.5 CBK22487.2 - 0.092 12.0 7.4 0.31 10.3 7.4 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4763) Ribosomal_L6e PF01159.19 CBK22487.2 - 0.34 11.5 1.6 1.5 9.4 1.6 2.0 1 0 0 1 1 1 0 Ribosomal protein L6e PP1_inhibitor PF05361.12 CBK22487.2 - 0.36 10.8 8.4 0.54 10.2 0.1 3.1 3 0 0 3 3 3 0 PKC-activated protein phosphatase-1 inhibitor HSP70 PF00012.20 CBK22488.2 - 6.4e-54 183.2 0.0 1.4e-53 182.1 0.0 1.4 1 1 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 CBK22488.2 - 7.4e-07 28.3 0.0 1.5e-06 27.3 0.0 1.5 1 1 0 1 1 1 1 MreB/Mbl protein Ribosomal_S13 PF00416.22 CBK22489.2 - 4.9e-50 169.2 1.0 5.8e-50 169.0 1.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S13/S18 FbpA PF05833.11 CBK22489.2 - 0.0026 16.6 0.0 0.003 16.4 0.0 1.2 1 0 0 1 1 1 1 Fibronectin-binding protein A N-terminus (FbpA) HHH_6 PF14579.6 CBK22489.2 - 0.0037 17.5 0.2 0.011 15.9 0.2 1.7 1 1 0 1 1 1 1 Helix-hairpin-helix motif DUF2746 PF10874.8 CBK22489.2 - 0.0045 17.4 0.0 0.0073 16.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2746) HHH_5 PF14520.6 CBK22489.2 - 0.034 14.8 0.1 0.065 13.8 0.1 1.5 1 0 0 1 1 1 0 Helix-hairpin-helix domain Period_C PF12114.8 CBK22489.2 - 0.17 11.4 0.0 0.23 11.0 0.0 1.2 1 0 0 1 1 1 0 Period protein 2/3C-terminal region DRMBL PF07522.14 CBK22491.2 - 1.8e-11 44.2 0.0 4.7e-11 42.9 0.0 1.7 1 0 0 1 1 1 1 DNA repair metallo-beta-lactamase Lactamase_B_2 PF12706.7 CBK22491.2 - 0.001 18.6 0.5 0.012 15.2 0.1 2.5 3 0 0 3 3 3 1 Beta-lactamase superfamily domain RSS_P20 PF11757.8 CBK22491.2 - 0.13 12.8 1.0 0.25 11.8 1.0 1.5 1 0 0 1 1 1 0 Suppressor of RNA silencing P21-like N-terminal domain Amidohydro_1 PF01979.20 CBK22492.2 - 1.4e-66 225.2 0.6 1.7e-66 224.9 0.6 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 CBK22492.2 - 1.2e-17 64.6 3.3 8.5e-15 55.2 0.1 2.5 2 1 0 2 2 2 2 Amidohydrolase family P33MONOX PF15302.6 CBK22492.2 - 0.03 14.0 0.0 0.056 13.1 0.0 1.3 1 0 0 1 1 1 0 P33 mono-oxygenase ASF1_hist_chap PF04729.13 CBK22493.2 - 5.3e-54 182.3 0.1 6.7e-54 182.0 0.1 1.1 1 0 0 1 1 1 1 ASF1 like histone chaperone SAC3_GANP PF03399.16 CBK22494.2 - 5.1e-19 68.8 11.8 3.8e-17 62.6 11.8 2.0 1 1 0 1 1 1 1 SAC3/GANP family TMP-TENI PF02581.17 CBK22495.2 - 8.3e-58 194.7 1.0 1.2e-57 194.2 1.0 1.2 1 0 0 1 1 1 1 Thiamine monophosphate synthase NMO PF03060.15 CBK22495.2 - 0.0048 16.3 0.3 0.007 15.8 0.3 1.3 1 0 0 1 1 1 1 Nitronate monooxygenase ThiG PF05690.14 CBK22495.2 - 0.078 12.3 2.8 0.11 11.8 1.3 1.9 2 0 0 2 2 2 0 Thiazole biosynthesis protein ThiG DUF561 PF04481.12 CBK22495.2 - 0.17 11.1 0.2 0.63 9.2 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF561) ANAPC_CDC26 PF10471.9 CBK22495.2 - 0.18 12.6 7.5 0.42 11.5 7.5 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex APC subunit CDC26 HCO3_cotransp PF00955.21 CBK22496.2 - 1.6e-40 139.4 0.2 2.3e-40 138.9 0.2 1.2 1 0 0 1 1 1 1 HCO3- transporter family WD40 PF00400.32 CBK22496.2 - 4.1e-16 59.1 13.8 0.00082 20.1 0.0 6.8 7 1 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBK22496.2 - 3.9e-08 33.5 1.9 0.069 13.5 0.0 4.3 2 2 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Collagen_bind_2 PF12904.7 CBK22496.2 - 0.0036 17.2 0.0 0.49 10.4 0.0 2.4 1 1 1 2 2 2 2 Putative collagen-binding domain of a collagenase HCO3_cotransp PF00955.21 CBK22497.2 - 1.9e-23 83.1 0.5 2.6e-23 82.7 0.5 1.2 1 0 0 1 1 1 1 HCO3- transporter family SAM_2 PF07647.17 CBK22497.2 - 0.00058 19.9 0.0 0.0015 18.6 0.0 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) He_PIG PF05345.12 CBK22498.2 - 5.8e-16 58.4 40.3 1.2e-05 25.3 5.5 5.5 4 1 0 4 4 4 3 Putative Ig domain BetaGal_dom4_5 PF13364.6 CBK22498.2 - 1.3e-08 35.4 8.5 0.00022 21.8 0.3 4.0 3 0 0 3 3 3 2 Beta-galactosidase jelly roll domain I-set PF07679.16 CBK22498.2 - 0.00029 20.8 2.6 3.4 7.8 0.0 5.6 5 0 0 5 5 5 1 Immunoglobulin I-set domain F5_F8_type_C PF00754.25 CBK22498.2 - 0.015 15.4 32.9 0.21 11.7 0.1 6.1 7 1 0 7 7 6 0 F5/8 type C domain Shisa PF13908.6 CBK22498.2 - 0.035 14.4 1.7 0.096 12.9 1.7 1.8 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator Orf78 PF06024.12 CBK22498.2 - 0.041 14.2 1.0 0.084 13.2 1.0 1.4 1 0 0 1 1 1 0 Orf78 (ac78) EphA2_TM PF14575.6 CBK22498.2 - 0.053 14.4 1.2 0.1 13.5 1.2 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain OAD_gamma PF04277.13 CBK22498.2 - 0.073 13.7 5.5 0.15 12.7 5.5 1.4 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain Baculo_11_kDa PF06143.11 CBK22498.2 - 0.086 12.4 3.2 0.17 11.4 3.2 1.4 1 0 0 1 1 1 0 Baculovirus 11 kDa family DUF5305 PF17231.2 CBK22498.2 - 0.16 11.3 2.4 0.36 10.2 2.4 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5305) ASFV_J13L PF05568.11 CBK22498.2 - 0.44 10.3 5.3 2.4 7.9 5.3 2.3 1 0 0 1 1 1 0 African swine fever virus J13L protein DUF5385 PF17359.2 CBK22498.2 - 1.3 8.5 2.7 2.1 7.8 2.7 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5385) TMEM154 PF15102.6 CBK22498.2 - 2.3 8.1 8.9 0.07 13.0 2.1 2.0 2 0 0 2 2 2 0 TMEM154 protein family RIFIN PF02009.16 CBK22498.2 - 2.6 7.9 4.0 5.5 6.8 4.0 1.5 1 0 0 1 1 1 0 Rifin Ribosomal_S8 PF00410.19 CBK22500.2 - 6.8e-21 74.5 0.0 1.1e-20 73.9 0.0 1.3 1 1 0 1 1 1 1 Ribosomal protein S8 SecY PF00344.20 CBK22501.2 - 7e-66 222.6 10.3 1e-65 222.0 10.3 1.2 1 0 0 1 1 1 1 SecY translocase Plug_translocon PF10559.9 CBK22501.2 - 1.2e-17 63.4 0.1 4.1e-17 61.7 0.1 2.0 1 0 0 1 1 1 1 Plug domain of Sec61p TMEM220 PF15071.6 CBK22501.2 - 0.36 11.6 3.0 9 7.1 0.5 3.0 2 0 0 2 2 2 0 Transmembrane family 220, helix DUF1430 PF07242.11 CBK22501.2 - 1.7 9.0 7.1 10 6.4 1.1 3.6 3 1 0 3 3 3 0 Protein of unknown function (DUF1430) Pkinase PF00069.25 CBK22502.2 - 2.1e-42 145.3 0.0 2.6e-42 145.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBK22502.2 - 2.2e-28 99.2 0.0 2.8e-28 98.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 CBK22502.2 - 6.6e-07 28.6 0.0 9.1e-07 28.1 0.0 1.1 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 CBK22502.2 - 0.00074 19.5 0.0 0.0025 17.8 0.0 1.8 1 1 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 CBK22502.2 - 0.0018 17.9 0.2 0.0048 16.5 0.0 1.6 1 1 0 2 2 2 1 RIO1 family Pkinase_fungal PF17667.1 CBK22502.2 - 0.005 15.7 0.0 0.0085 14.9 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Choline_kinase PF01633.20 CBK22502.2 - 0.065 12.8 0.1 0.086 12.4 0.1 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase Kdo PF06293.14 CBK22502.2 - 0.099 12.0 0.1 0.17 11.3 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pox_ser-thr_kin PF05445.11 CBK22502.2 - 0.13 11.2 0.0 0.19 10.7 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase YfkD PF14167.6 CBK22502.2 - 0.22 10.7 0.1 0.37 9.9 0.1 1.3 1 0 0 1 1 1 0 YfkD-like protein Pkinase PF00069.25 CBK22504.2 - 4.6e-44 150.8 0.0 5.6e-44 150.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBK22504.2 - 3.1e-30 105.3 0.0 3.7e-30 105.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CBK22504.2 - 0.024 13.4 0.0 0.06 12.1 0.0 1.6 2 0 0 2 2 2 0 Fungal protein kinase Neurochondrin PF05536.11 CBK22506.2 - 0.027 12.9 2.2 0.02 13.3 0.6 1.5 2 0 0 2 2 2 0 Neurochondrin dsrm PF00035.26 CBK22507.2 - 1.8e-10 41.4 0.0 2.7e-10 40.8 0.0 1.2 1 0 0 1 1 1 1 Double-stranded RNA binding motif Peptidase_M1 PF01433.20 CBK22508.2 - 1.9e-43 148.6 0.0 2.7e-43 148.1 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M1 domain Peptidase_M1_N PF17900.1 CBK22508.2 - 5.5e-12 46.2 0.8 5.5e-12 46.2 0.8 1.8 2 0 0 2 2 2 1 Peptidase M1 N-terminal domain E1-E2_ATPase PF00122.20 CBK22511.2 - 6.7e-16 58.3 0.0 1.5e-15 57.2 0.0 1.5 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.26 CBK22511.2 - 3.2e-12 47.2 0.1 2.1e-11 44.5 0.1 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 CBK22511.2 - 4.4e-05 23.3 0.3 0.00034 20.4 0.3 2.1 1 1 1 2 2 2 1 haloacid dehalogenase-like hydrolase DNA_pol_B_exo1 PF03104.19 CBK22512.2 - 1.9e-61 208.1 0.9 4.7e-61 206.8 0.3 2.1 2 1 0 2 2 2 1 DNA polymerase family B, exonuclease domain DUF1744 PF08490.12 CBK22512.2 - 1.3e-39 136.0 0.0 1.7e-37 129.0 0.0 2.2 1 1 0 1 1 1 1 Domain of unknown function (DUF1744) DNA_pol_B PF00136.21 CBK22512.2 - 1e-13 50.9 0.0 1.5e-12 47.0 0.0 2.6 3 0 0 3 3 3 1 DNA polymerase family B DNA_pol_B_exo2 PF10108.9 CBK22512.2 - 2.2e-06 27.5 1.7 4.3e-05 23.3 1.7 2.5 1 1 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB RNase_H_2 PF13482.6 CBK22512.2 - 5.8e-05 23.1 0.0 0.00022 21.3 0.0 2.0 1 0 0 1 1 1 1 RNase_H superfamily C1_1 PF00130.22 CBK22513.2 - 0.7 9.8 7.3 3.2 7.7 0.7 3.0 2 1 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) TF_Zn_Ribbon PF08271.12 CBK22513.2 - 2.2 7.8 6.6 1.3 8.6 0.7 2.6 2 0 0 2 2 2 0 TFIIB zinc-binding PHD PF00628.29 CBK22513.2 - 4.6 7.2 12.3 0.1 12.5 1.2 2.6 2 1 0 2 2 2 0 PHD-finger DUF2318 PF10080.9 CBK22513.2 - 5.2 7.2 13.7 8.2 6.6 5.5 3.3 2 1 1 3 3 3 0 Predicted membrane protein (DUF2318) Pro_isomerase PF00160.21 CBK22514.2 - 6.7e-46 156.4 0.0 6.7e-46 156.4 0.0 2.1 2 1 0 2 2 2 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DnaJ_CXXCXGXG PF00684.19 CBK22515.2 - 4.2e-10 39.8 11.6 7e-10 39.1 11.6 1.4 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 CBK22515.2 - 2.9e-05 23.9 7.6 0.013 15.4 1.0 2.4 2 0 0 2 2 2 2 Tryptophan RNA-binding attenuator protein inhibitory protein HypA PF01155.19 CBK22515.2 - 0.00062 19.8 3.7 0.042 13.9 0.1 2.2 2 0 0 2 2 2 2 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DnaJ PF00226.31 CBK22515.2 - 0.0024 18.0 0.1 0.004 17.2 0.1 1.4 1 0 0 1 1 1 1 DnaJ domain DZR PF12773.7 CBK22515.2 - 0.0093 16.0 7.3 0.024 14.7 7.3 1.7 1 1 0 1 1 1 1 Double zinc ribbon FdhE PF04216.12 CBK22515.2 - 0.037 13.9 7.6 2.5 7.9 7.6 2.1 1 1 0 1 1 1 0 Protein involved in formate dehydrogenase formation TackOD1 PF18551.1 CBK22515.2 - 0.3 10.7 7.6 1.4 8.6 0.9 2.2 1 1 1 2 2 2 0 Thaumarchaeal output domain 1 OrfB_Zn_ribbon PF07282.11 CBK22515.2 - 2.7 8.0 14.6 3 7.9 5.1 2.3 1 1 1 2 2 2 0 Putative transposase DNA-binding domain zinc_ribbon_2 PF13240.6 CBK22515.2 - 5.6 6.8 18.9 54 3.7 0.7 4.2 2 2 2 4 4 4 0 zinc-ribbon domain Lar_restr_allev PF14354.6 CBK22515.2 - 6.2 7.3 11.2 32 5.0 5.2 3.0 1 1 1 2 2 2 0 Restriction alleviation protein Lar Zn_Tnp_IS1595 PF12760.7 CBK22515.2 - 6.8 6.7 18.1 15 5.7 0.7 3.7 1 1 3 4 4 4 0 Transposase zinc-ribbon domain Aminotran_5 PF00266.19 CBK22516.2 - 1.7e-33 116.1 0.0 2.6e-33 115.5 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V MORN PF02493.20 CBK22516.2 - 1.1e-16 59.6 33.9 0.0064 16.3 5.3 9.0 8 0 0 8 8 8 8 MORN repeat GST_C_2 PF13410.6 CBK22517.2 - 1.5e-05 24.9 0.0 3.1e-05 23.9 0.0 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 CBK22517.2 - 0.0012 19.0 0.0 0.0029 17.8 0.0 1.8 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 CBK22517.2 - 0.0042 17.2 0.0 0.0086 16.2 0.0 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain WD40 PF00400.32 CBK22519.2 - 4.2e-07 30.6 3.3 0.037 14.9 0.2 3.5 3 0 0 3 3 3 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBK22519.2 - 1.2e-05 25.5 0.0 0.049 13.9 0.0 3.3 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain BBS2_Mid PF14783.6 CBK22519.2 - 0.019 15.0 0.0 0.92 9.6 0.0 3.0 2 1 1 3 3 3 0 Ciliary BBSome complex subunit 2, middle region U-box PF04564.15 CBK22520.2 - 0.0057 16.8 0.0 0.0066 16.6 0.0 1.2 1 0 0 1 1 1 1 U-box domain EC042_2821 PF18740.1 CBK22520.2 - 0.13 12.2 0.0 0.14 12.0 0.0 1.0 1 0 0 1 1 1 0 EC042_2821-lke REase NMU PF02070.15 CBK22521.2 - 0.016 15.1 5.8 0.35 10.8 2.2 3.2 2 0 0 2 2 2 0 Neuromedin U ORC6 PF05460.13 CBK22521.2 - 0.051 12.8 3.5 0.092 12.0 3.5 1.4 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Importin_rep_6 PF18829.1 CBK22521.2 - 3.6 7.7 6.3 0.27 11.4 1.0 1.8 2 0 0 2 2 2 0 Importin repeat 6 CK_II_beta PF01214.18 CBK22522.2 - 7.7e-41 139.9 0.0 8.8e-41 139.7 0.0 1.0 1 0 0 1 1 1 1 Casein kinase II regulatory subunit RabGAP-TBC PF00566.18 CBK22523.2 - 3.3e-27 95.5 6.1 3.3e-27 95.5 6.1 2.5 2 0 0 2 2 2 1 Rab-GTPase-TBC domain G-patch PF01585.23 CBK22523.2 - 3.6e-13 49.2 5.0 7e-13 48.2 5.0 1.5 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 CBK22523.2 - 1.4e-08 34.7 1.9 1.4e-08 34.7 1.9 2.6 2 0 0 2 2 2 1 G-patch domain Rhodanese PF00581.20 CBK22523.2 - 2.6e-07 31.1 3.6 4.1e-07 30.5 0.0 2.8 3 0 0 3 3 3 1 Rhodanese-like domain eIF-1a PF01176.19 CBK22524.2 - 2e-14 53.1 0.0 3.5e-14 52.3 0.0 1.4 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 sCache_3_2 PF17203.4 CBK22524.2 - 0.064 13.4 0.0 2.6 8.2 0.0 2.1 1 1 0 2 2 2 0 Single cache domain 3 DNA_pol_phi PF04931.13 CBK22524.2 - 2.2 6.3 19.1 2.5 6.1 19.1 1.1 1 0 0 1 1 1 0 DNA polymerase phi tRNA-synt_1e PF01406.19 CBK22525.2 - 2.9e-100 335.5 0.2 4.2e-100 335.0 0.2 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.11 CBK22525.2 - 9.2e-11 41.1 0.0 0.00032 19.6 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 CBK22525.2 - 7.5e-05 21.2 0.0 0.00018 19.9 0.0 1.6 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) PhaP_Bmeg PF09602.10 CBK22525.2 - 0.0018 18.2 0.7 0.0044 17.0 0.7 1.6 1 0 0 1 1 1 1 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) tRNA-synt_1f PF01921.18 CBK22525.2 - 0.024 13.5 0.0 0.062 12.2 0.0 1.6 1 0 0 1 1 1 0 tRNA synthetases class I (K) tRNA-synt_1c PF00749.21 CBK22525.2 - 0.061 12.2 0.2 0.16 10.8 0.0 1.7 2 0 0 2 2 2 0 tRNA synthetases class I (E and Q), catalytic domain RecG_N PF17190.4 CBK22525.2 - 0.22 12.3 1.1 33 5.3 0.2 2.7 2 0 0 2 2 2 0 RecG N-terminal helical domain HSP70 PF00012.20 CBK22526.2 - 1.3e-53 182.1 0.0 1.7e-53 181.8 0.0 1.1 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 CBK22526.2 - 3.2e-11 42.6 0.0 4.6e-09 35.6 0.0 2.8 2 1 0 2 2 2 1 MreB/Mbl protein FtsA PF14450.6 CBK22526.2 - 0.11 12.9 0.2 0.79 10.2 0.2 2.6 1 1 0 1 1 1 0 Cell division protein FtsA Pan_kinase PF03309.14 CBK22526.2 - 0.22 11.3 0.0 0.57 10.0 0.0 1.7 1 0 0 1 1 1 0 Type III pantothenate kinase Inhibitor_I34 PF10466.9 CBK22526.2 - 0.44 11.2 1.8 0.72 10.5 0.5 2.0 2 0 0 2 2 2 0 Saccharopepsin inhibitor I34 HSP70 PF00012.20 CBK22527.2 - 3.2e-24 85.1 0.1 6.1e-24 84.2 0.0 1.4 2 0 0 2 2 2 1 Hsp70 protein MreB_Mbl PF06723.13 CBK22527.2 - 0.02 13.7 0.0 0.077 11.8 0.0 1.8 1 1 0 1 1 1 0 MreB/Mbl protein Topo_Zn_Ribbon PF08272.11 CBK22527.2 - 0.054 13.2 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 Topoisomerase I zinc-ribbon-like IF-2B PF01008.17 CBK22528.2 - 8.2e-25 87.6 0.0 9.5e-25 87.4 0.0 1.0 1 0 0 1 1 1 1 Initiation factor 2 subunit family CSD PF00313.22 CBK22529.2 - 0.00034 20.4 0.0 0.00052 19.8 0.0 1.4 1 0 0 1 1 1 1 'Cold-shock' DNA-binding domain Ribosomal_L21p PF00829.21 CBK22530.2 - 3e-29 101.2 1.0 4.1e-29 100.8 1.0 1.2 1 0 0 1 1 1 1 Ribosomal prokaryotic L21 protein PIN_10 PF18478.1 CBK22530.2 - 0.098 12.9 0.0 0.17 12.1 0.0 1.4 1 0 0 1 1 1 0 PIN like domain AAA PF00004.29 CBK22531.2 - 1.5e-15 57.8 0.0 3.2e-15 56.7 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.6 CBK22531.2 - 2.5e-11 43.6 0.0 8.7e-09 35.4 0.0 2.3 1 1 0 1 1 1 1 DNA polymerase III, delta subunit Rep_fac_C PF08542.11 CBK22531.2 - 3e-09 37.1 0.1 5.1e-09 36.4 0.1 1.4 1 0 0 1 1 1 1 Replication factor C C-terminal domain AAA_22 PF13401.6 CBK22531.2 - 1.1e-05 25.8 0.0 0.0013 19.1 0.0 2.6 1 1 0 1 1 1 1 AAA domain AAA_11 PF13086.6 CBK22531.2 - 1.1e-05 25.4 0.0 1.9e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 CBK22531.2 - 1.1e-05 25.8 0.0 7.1e-05 23.2 0.0 2.2 1 1 1 2 2 2 1 AAA ATPase domain ResIII PF04851.15 CBK22531.2 - 1.4e-05 25.1 0.0 0.00034 20.7 0.0 2.3 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit TIP49_C PF17856.1 CBK22531.2 - 2.6e-05 24.3 0.1 7.5e-05 22.8 0.0 1.8 2 0 0 2 2 1 1 TIP49 AAA-lid domain AAA_assoc_2 PF16193.5 CBK22531.2 - 0.00018 21.7 0.0 0.00045 20.5 0.0 1.7 1 0 0 1 1 1 1 AAA C-terminal domain ABC_tran PF00005.27 CBK22531.2 - 0.0014 19.2 0.0 1.3 9.6 0.0 2.3 2 0 0 2 2 2 2 ABC transporter Mg_chelatase PF01078.21 CBK22531.2 - 0.0015 18.0 0.0 0.01 15.2 0.0 2.0 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_24 PF13479.6 CBK22531.2 - 0.0027 17.5 0.0 0.0049 16.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.12 CBK22531.2 - 0.0037 17.0 0.1 0.012 15.3 0.0 1.8 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_14 PF13173.6 CBK22531.2 - 0.011 15.8 0.0 0.025 14.6 0.0 1.6 1 1 1 2 2 2 0 AAA domain AAA_19 PF13245.6 CBK22531.2 - 0.02 15.2 0.1 0.17 12.2 0.0 2.2 1 1 1 2 2 2 0 AAA domain ATPase_2 PF01637.18 CBK22531.2 - 0.021 14.8 0.0 0.13 12.2 0.0 2.1 2 1 0 2 2 2 0 ATPase domain predominantly from Archaea AAA_5 PF07728.14 CBK22531.2 - 0.022 14.8 0.0 0.076 13.0 0.0 1.9 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_30 PF13604.6 CBK22531.2 - 0.028 14.2 0.0 0.062 13.0 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_7 PF12775.7 CBK22531.2 - 0.036 13.6 0.0 0.066 12.7 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region DUF815 PF05673.13 CBK22531.2 - 0.036 13.2 0.0 0.058 12.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) TniB PF05621.11 CBK22531.2 - 0.066 12.6 0.0 0.42 10.0 0.0 2.0 2 0 0 2 2 2 0 Bacterial TniB protein TIP49 PF06068.13 CBK22531.2 - 0.085 12.0 0.0 0.18 11.0 0.0 1.6 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_28 PF13521.6 CBK22531.2 - 0.14 12.4 0.0 0.23 11.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.15 CBK22531.2 - 0.15 12.0 0.0 0.78 9.6 0.0 2.0 2 0 0 2 2 2 0 Rad17 P-loop domain Na_H_antiporter PF03553.14 CBK22532.2 - 1.2e-48 165.9 12.7 1.2e-48 165.9 12.7 2.6 1 1 0 2 2 2 1 Na+/H+ antiporter family SieB PF14163.6 CBK22532.2 - 0.0026 17.3 1.0 0.4 10.2 0.0 2.9 2 1 0 2 2 2 2 Super-infection exclusion protein B MscS_TM PF12794.7 CBK22532.2 - 0.0069 15.3 9.6 0.58 9.0 0.0 3.8 3 2 1 4 4 4 2 Mechanosensitive ion channel inner membrane domain 1 Preseq_ALAS PF09029.10 CBK22532.2 - 0.11 12.9 0.0 2.4 8.6 0.1 2.3 2 0 0 2 2 2 0 5-aminolevulinate synthase presequence ABC1 PF03109.16 CBK22533.2 - 1.1e-21 77.2 0.0 1.7e-21 76.6 0.0 1.4 1 0 0 1 1 1 1 ABC1 family YrbL-PhoP_reg PF10707.9 CBK22534.2 - 0.051 13.1 0.1 0.11 12.0 0.0 1.6 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL Methyltransf_23 PF13489.6 CBK22535.2 - 5.8e-14 52.2 0.0 8.6e-14 51.7 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CBK22535.2 - 1.7e-09 38.3 0.1 1.1e-08 35.7 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 CBK22535.2 - 6.2e-08 33.3 0.0 1.6e-07 32.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CBK22535.2 - 4.7e-06 27.2 0.0 1.3e-05 25.7 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 CBK22535.2 - 0.0023 17.5 0.0 0.0041 16.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_2 PF00891.18 CBK22535.2 - 0.021 14.1 0.0 0.031 13.6 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase domain DUF4457 PF14652.6 CBK22536.2 - 2.2e-98 329.5 0.0 2.6e-98 329.3 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4457) Sad1_UNC PF07738.13 CBK22536.2 - 0.14 12.2 0.0 0.67 10.0 0.0 2.0 2 0 0 2 2 2 0 Sad1 / UNC-like C-terminal AhpC-TSA PF00578.21 CBK22537.2 - 8e-36 122.7 0.0 1.1e-35 122.3 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 CBK22537.2 - 1.2e-11 44.6 0.0 1.5e-11 44.2 0.0 1.1 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.9 CBK22537.2 - 1.8e-11 43.7 0.0 3.8e-11 42.6 0.0 1.5 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin DNA_pol_B_2 PF03175.13 CBK22538.2 - 1.8e-16 60.1 15.1 8.2e-14 51.3 9.1 2.3 2 0 0 2 2 2 2 DNA polymerase type B, organellar and viral ACBP PF00887.19 CBK22540.2 - 8.6e-29 99.6 0.4 1e-28 99.4 0.4 1.0 1 0 0 1 1 1 1 Acyl CoA binding protein FERM_M PF00373.18 CBK22540.2 - 0.14 12.6 0.1 0.25 11.8 0.1 1.3 1 1 0 1 1 1 0 FERM central domain DUF4090 PF13319.6 CBK22541.2 - 0.051 13.8 1.0 0.064 13.5 1.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4090) IATP PF04568.12 CBK22541.2 - 0.16 12.4 5.6 0.26 11.7 5.6 1.5 1 1 0 1 1 1 0 Mitochondrial ATPase inhibitor, IATP RabGAP-TBC PF00566.18 CBK22543.2 - 1.1e-18 67.8 0.3 5.9e-18 65.3 0.1 2.3 2 1 0 2 2 2 1 Rab-GTPase-TBC domain PDZ_6 PF17820.1 CBK22543.2 - 0.00067 19.4 0.1 0.21 11.5 0.0 2.6 2 0 0 2 2 2 2 PDZ domain PDZ PF00595.24 CBK22543.2 - 0.042 14.2 0.5 0.94 9.9 0.0 2.6 3 0 0 3 3 3 0 PDZ domain TraH PF06122.11 CBK22543.2 - 0.12 11.7 0.0 0.18 11.0 0.0 1.2 1 0 0 1 1 1 0 Conjugative relaxosome accessory transposon protein PDZ_2 PF13180.6 CBK22543.2 - 0.22 11.9 0.0 0.67 10.3 0.0 1.8 2 0 0 2 2 2 0 PDZ domain RabGAP-TBC PF00566.18 CBK22544.2 - 7.1e-14 52.0 1.9 8e-14 51.8 1.9 1.0 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Glyco_hydro_35 PF01301.19 CBK22545.2 - 2.3e-70 237.7 3.8 3.5e-70 237.1 3.8 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 BetaGal_dom4_5 PF13364.6 CBK22545.2 - 1.3e-09 38.6 2.4 1.4e-06 28.8 0.1 3.4 3 0 0 3 3 3 2 Beta-galactosidase jelly roll domain GHD PF17834.1 CBK22545.2 - 7e-06 26.0 0.6 5.3e-05 23.2 0.5 2.2 2 0 0 2 2 2 1 Beta-sandwich domain in beta galactosidase Glyco_hydro_42 PF02449.15 CBK22545.2 - 3.8e-05 23.2 0.2 7.5e-05 22.2 0.2 1.4 1 0 0 1 1 1 1 Beta-galactosidase Glyco_hydro_2_N PF02837.18 CBK22545.2 - 0.037 13.9 0.1 0.12 12.3 0.1 1.8 1 0 0 1 1 1 0 Glycosyl hydrolases family 2, sugar binding domain Xpo1 PF08389.12 CBK22546.2 - 1.2e-13 51.4 6.6 6e-12 45.9 3.3 2.7 2 0 0 2 2 2 2 Exportin 1-like protein IBN_N PF03810.19 CBK22546.2 - 0.024 14.6 0.1 0.024 14.6 0.1 2.4 2 0 0 2 2 2 0 Importin-beta N-terminal domain UTP15_C PF09384.10 CBK22546.2 - 0.031 14.0 0.0 9.7 5.9 0.0 2.7 2 0 0 2 2 2 0 UTP15 C terminal HEAT_2 PF13646.6 CBK22546.2 - 0.032 14.6 0.1 0.21 12.0 0.0 2.4 3 0 0 3 3 3 0 HEAT repeats Arm PF00514.23 CBK22546.2 - 0.13 12.4 0.3 9.8 6.4 0.0 3.1 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat CAAP1 PF15335.6 CBK22546.2 - 0.22 12.1 1.9 3 8.4 0.1 3.6 3 1 0 3 3 3 0 Caspase activity and apoptosis inhibitor 1 RNaseH_C PF09293.10 CBK22547.2 - 0.029 14.7 0.2 0.12 12.8 0.2 2.0 1 0 0 1 1 1 0 T4 RNase H, C terminal AAA_5 PF07728.14 CBK22548.2 - 6.7e-11 42.3 0.0 0.00019 21.5 0.0 3.3 3 0 0 3 3 3 2 AAA domain (dynein-related subfamily) Synaptobrevin PF00957.21 CBK22549.2 - 1.3e-10 40.9 0.0 1.4e-10 40.8 0.0 1.0 1 0 0 1 1 1 1 Synaptobrevin Sedlin_N PF04628.13 CBK22550.2 - 0.044 13.9 0.2 0.065 13.4 0.2 1.4 1 1 0 1 1 1 0 Sedlin, N-terminal conserved region G10 PF01125.17 CBK22551.2 - 1.3e-50 170.9 9.0 1.5e-50 170.8 9.0 1.0 1 0 0 1 1 1 1 G10 protein DUF2387 PF09526.10 CBK22551.2 - 2.8 8.2 10.2 0.57 10.4 0.5 2.5 1 1 1 2 2 2 0 Probable metal-binding protein (DUF2387) CBFD_NFYB_HMF PF00808.23 CBK22553.2 - 1.5e-25 89.2 0.1 1.9e-25 88.9 0.1 1.1 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 CBK22553.2 - 4.7e-05 23.8 0.0 5.8e-05 23.5 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 CBK22553.2 - 0.0025 17.9 0.0 0.0033 17.5 0.0 1.1 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold PAN_3 PF08277.12 CBK22553.2 - 0.021 14.6 0.1 0.029 14.2 0.1 1.2 1 0 0 1 1 1 0 PAN-like domain TFIID-18kDa PF02269.16 CBK22553.2 - 0.025 14.6 0.0 0.042 13.9 0.0 1.3 1 0 0 1 1 1 0 Transcription initiation factor IID, 18kD subunit GED PF02212.18 CBK22554.2 - 1.5e-21 76.3 4.0 3.1e-21 75.3 4.0 1.5 1 0 0 1 1 1 1 Dynamin GTPase effector domain PH PF00169.29 CBK22554.2 - 2.7e-05 24.6 0.1 4.2e-05 24.0 0.1 1.3 1 0 0 1 1 1 1 PH domain TFIIF_beta PF02270.15 CBK22554.2 - 0.0088 16.2 0.2 0.82 9.9 0.0 2.5 2 0 0 2 2 2 1 TFIIF, beta subunit HTH domain REV PF00424.18 CBK22554.2 - 0.04 14.0 0.1 0.093 12.8 0.1 1.6 1 0 0 1 1 1 0 REV protein (anti-repression trans-activator protein) PH_8 PF15409.6 CBK22554.2 - 0.054 13.8 0.5 0.17 12.2 0.2 2.0 2 0 0 2 2 2 0 Pleckstrin homology domain DUF2018 PF09442.10 CBK22554.2 - 0.1 13.6 3.5 0.23 12.5 0.6 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF2018) DUF3510 PF12022.8 CBK22554.2 - 0.14 12.5 1.9 1.3 9.5 0.2 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF3510) Dynamin_N PF00350.23 CBK22555.2 - 2.4e-51 174.1 0.0 3.4e-51 173.6 0.0 1.2 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.20 CBK22555.2 - 1.1e-26 93.7 0.1 1.5e-26 93.2 0.1 1.2 1 0 0 1 1 1 1 Dynamin central region MMR_HSR1 PF01926.23 CBK22555.2 - 3.2e-05 24.0 0.0 8e-05 22.7 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 CBK22555.2 - 0.042 13.4 0.2 9.8 5.7 0.0 2.2 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_28 PF13521.6 CBK22555.2 - 0.14 12.4 0.0 0.26 11.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain 2-oxoacid_dh PF00198.23 CBK22556.2 - 9.6e-70 234.6 0.2 1.3e-69 234.3 0.2 1.1 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 CBK22556.2 - 1.2e-17 63.5 0.3 3e-17 62.2 0.3 1.7 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.17 CBK22556.2 - 5.2e-10 39.5 0.1 1.4e-09 38.1 0.1 1.8 2 0 0 2 2 2 1 e3 binding domain Biotin_lipoyl_2 PF13533.6 CBK22556.2 - 4.9e-07 29.5 0.0 2.4e-06 27.3 0.0 2.2 1 1 1 2 2 2 1 Biotin-lipoyl like HlyD_3 PF13437.6 CBK22556.2 - 0.0079 16.9 0.1 0.035 14.8 0.0 2.1 1 1 1 2 2 2 1 HlyD family secretion protein PYNP_C PF07831.13 CBK22556.2 - 0.055 13.1 0.0 6 6.6 0.0 2.3 2 0 0 2 2 2 0 Pyrimidine nucleoside phosphorylase C-terminal domain CCDC53 PF10152.9 CBK22556.2 - 0.18 12.2 4.2 0.37 11.2 4.2 1.5 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex PepSY_TM PF03929.16 CBK22556.2 - 0.55 9.8 2.2 0.82 9.3 2.2 1.3 1 0 0 1 1 1 0 PepSY-associated TM region TFIIA PF03153.13 CBK22556.2 - 0.56 10.2 4.4 0.67 9.9 4.4 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF1631 PF07793.11 CBK22556.2 - 2.8 6.3 10.4 3.6 5.9 10.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1631) Histone PF00125.24 CBK22558.2 - 6.8e-53 178.5 3.8 7.5e-53 178.4 3.8 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 CBK22558.2 - 5.4e-05 23.5 0.1 7.8e-05 23.0 0.1 1.3 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 CBK22558.2 - 0.00048 20.2 0.2 0.00048 20.2 0.2 1.6 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold PAF PF15715.5 CBK22558.2 - 0.00081 20.0 1.1 0.00091 19.8 1.1 1.1 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CBFD_NFYB_HMF PF00808.23 CBK22558.2 - 0.0044 17.3 0.1 0.0088 16.3 0.1 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone EPL1 PF10513.9 CBK22560.2 - 3.2e-09 37.4 0.2 7.7e-09 36.1 0.2 1.6 1 0 0 1 1 1 1 Enhancer of polycomb-like KH_1 PF00013.29 CBK22561.2 - 0.001 18.8 2.0 0.0015 18.3 1.1 1.7 2 0 0 2 2 2 1 KH domain KH_8 PF17903.1 CBK22561.2 - 0.025 14.7 0.0 0.048 13.7 0.0 1.5 1 0 0 1 1 1 0 Krr1 KH1 domain tRNA-synt_2b PF00587.25 CBK22562.2 - 6.7e-39 133.7 0.1 1.1e-38 133.0 0.1 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.22 CBK22562.2 - 9.7e-24 83.7 4.7 1.9e-23 82.8 4.7 1.4 1 0 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain L_lactis_ph-MCP PF06673.11 CBK22562.2 - 0.31 10.0 4.7 0.51 9.3 4.7 1.3 1 0 0 1 1 1 0 Lactococcus lactis bacteriophage major capsid protein zf-Sec23_Sec24 PF04810.15 CBK22563.2 - 0.00019 21.4 1.6 0.00039 20.4 1.6 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Sec23_BS PF08033.12 CBK22563.2 - 0.011 16.4 0.4 0.2 12.4 0.1 2.4 2 0 0 2 2 2 0 Sec23/Sec24 beta-sandwich domain Gelsolin PF00626.22 CBK22564.2 - 1.9e-06 27.6 0.0 5.4e-06 26.2 0.0 1.8 2 0 0 2 2 2 1 Gelsolin repeat DUF4573 PF15140.6 CBK22565.2 - 0.005 16.7 5.9 0.0083 15.9 5.9 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4573) TFIIB_C_1 PF18542.1 CBK22565.2 - 0.015 15.3 0.1 0.03 14.4 0.1 1.4 1 0 0 1 1 1 0 Transcription factor IIB C-terminal module 1 MotB_plug PF13677.6 CBK22565.2 - 0.061 12.9 0.2 0.13 11.9 0.2 1.5 1 0 0 1 1 1 0 Membrane MotB of proton-channel complex MotA/MotB Thioredoxin PF00085.20 CBK22566.2 - 1.3e-16 60.5 0.1 7.8e-11 41.9 0.1 2.2 2 0 0 2 2 2 2 Thioredoxin ERp29 PF07749.12 CBK22566.2 - 2.6e-06 28.2 0.4 7.5e-06 26.8 0.4 1.8 1 0 0 1 1 1 1 Endoplasmic reticulum protein ERp29, C-terminal domain OST3_OST6 PF04756.13 CBK22566.2 - 0.012 15.0 0.0 0.017 14.5 0.0 1.3 1 0 0 1 1 1 0 OST3 / OST6 family, transporter family Thioredoxin_2 PF13098.6 CBK22566.2 - 0.035 14.6 0.5 18 5.9 0.0 2.9 2 1 0 2 2 2 0 Thioredoxin-like domain Ssu72 PF04722.13 CBK22566.2 - 0.037 13.6 0.0 0.27 10.8 0.0 2.2 2 0 0 2 2 2 0 Ssu72-like protein Thioredoxin_3 PF13192.6 CBK22566.2 - 0.21 11.6 0.7 55 3.9 0.0 3.2 3 0 0 3 3 3 0 Thioredoxin domain Mito_carr PF00153.27 CBK22567.2 - 1.7e-41 140.1 2.3 3.6e-15 55.7 0.0 3.4 3 1 0 3 3 3 3 Mitochondrial carrier protein PS_Dcarbxylase PF02666.15 CBK22568.2 - 4.8e-46 156.8 0.0 6.2e-46 156.5 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase Biotin_lipoyl PF00364.22 CBK22568.2 - 0.026 14.3 0.0 0.049 13.5 0.0 1.4 1 0 0 1 1 1 0 Biotin-requiring enzyme Peptidase_M23 PF01551.22 CBK22568.2 - 0.16 12.2 0.0 0.28 11.4 0.0 1.3 1 0 0 1 1 1 0 Peptidase family M23 DUF4187 PF13821.6 CBK22569.2 - 1.9e-18 66.0 3.5 5.3e-18 64.5 3.5 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) G-patch PF01585.23 CBK22569.2 - 1.1e-15 57.3 5.9 2.4e-15 56.2 5.9 1.6 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 CBK22569.2 - 1.6e-07 31.3 1.6 3.6e-07 30.2 1.6 1.7 1 0 0 1 1 1 1 G-patch domain zf-C2H2_jaz PF12171.8 CBK22569.2 - 0.069 13.5 2.9 0.13 12.6 2.9 1.5 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding BAF PF02961.14 CBK22569.2 - 0.092 13.2 0.1 0.17 12.4 0.1 1.5 1 0 0 1 1 1 0 Barrier to autointegration factor DNA_pol_B PF00136.21 CBK22570.2 - 1.1e-109 367.2 3.5 1.1e-109 367.2 3.5 1.4 2 0 0 2 2 2 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 CBK22570.2 - 5.9e-06 25.7 2.2 1.7e-05 24.2 0.0 2.6 3 0 0 3 3 3 1 DNA polymerase family B, exonuclease domain DNA_pol_B_2 PF03175.13 CBK22570.2 - 3.6e-05 22.8 0.1 3.6e-05 22.8 0.1 2.9 3 1 1 4 4 4 1 DNA polymerase type B, organellar and viral DUF1744 PF08490.12 CBK22570.2 - 0.062 11.9 0.1 0.1 11.2 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1744) Cytomega_UL84 PF06284.11 CBK22570.2 - 0.063 11.7 3.5 0.091 11.2 3.5 1.1 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein Gti1_Pac2 PF09729.9 CBK22570.2 - 0.15 12.2 1.6 0.29 11.2 1.6 1.4 1 0 0 1 1 1 0 Gti1/Pac2 family CobT PF06213.12 CBK22570.2 - 1.7 8.0 7.3 2.5 7.4 5.4 2.0 2 0 0 2 2 2 0 Cobalamin biosynthesis protein CobT Metallophos PF00149.28 CBK22571.2 - 7.1e-33 114.8 0.3 1e-32 114.3 0.3 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 CBK22571.2 - 0.01 16.3 0.7 0.023 15.1 0.1 1.9 2 0 0 2 2 2 0 Serine-threonine protein phosphatase N-terminal domain DUF5378 PF17349.2 CBK22571.2 - 0.14 11.5 0.0 0.21 10.9 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5378) RPN6_N PF18055.1 CBK22572.2 - 2.1e-21 76.5 3.1 4.5e-21 75.4 3.1 1.6 1 0 0 1 1 1 1 26S proteasome regulatory subunit RPN6 N-terminal domain TPR_2 PF07719.17 CBK22572.2 - 0.083 13.0 0.2 8.3 6.8 0.6 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.6 CBK22572.2 - 0.084 13.1 0.2 0.94 9.9 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF4912 PF16258.5 CBK22572.2 - 0.099 12.9 0.0 0.25 11.6 0.0 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4912) Peptidase_M41 PF01434.18 CBK22573.2 - 2.6e-50 170.9 0.0 4.2e-50 170.3 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 CBK22573.2 - 8.6e-38 129.8 0.1 2.3e-37 128.4 0.0 1.8 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 CBK22573.2 - 8.7e-06 26.2 2.1 0.00097 19.6 0.1 3.2 2 1 1 3 3 3 1 AAA ATPase domain AAA_5 PF07728.14 CBK22573.2 - 2.8e-05 24.2 0.0 0.00011 22.2 0.0 2.1 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 CBK22573.2 - 7.3e-05 22.6 0.0 0.00021 21.1 0.0 1.8 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain TIP49 PF06068.13 CBK22573.2 - 0.00032 20.0 0.0 0.00056 19.2 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_lid_3 PF17862.1 CBK22573.2 - 0.00056 19.7 0.1 0.0013 18.5 0.1 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_22 PF13401.6 CBK22573.2 - 0.00058 20.1 0.1 0.042 14.1 0.1 2.7 1 1 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 CBK22573.2 - 0.0012 18.2 0.3 0.0026 17.2 0.3 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 CBK22573.2 - 0.0057 16.4 0.2 0.029 14.1 0.0 2.3 3 0 0 3 3 3 1 IstB-like ATP binding protein AAA_2 PF07724.14 CBK22573.2 - 0.011 15.9 0.0 0.046 13.8 0.0 2.1 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) AAA_33 PF13671.6 CBK22573.2 - 0.013 15.6 0.0 0.046 13.9 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 CBK22573.2 - 0.018 15.6 0.4 0.11 13.0 0.0 2.4 3 0 0 3 3 2 0 AAA domain AAA_7 PF12775.7 CBK22573.2 - 0.024 14.2 0.0 0.1 12.1 0.0 2.0 1 1 0 1 1 1 0 P-loop containing dynein motor region ATPase PF06745.13 CBK22573.2 - 0.038 13.3 0.0 0.078 12.3 0.0 1.6 1 0 0 1 1 1 0 KaiC Sigma54_activat PF00158.26 CBK22573.2 - 0.071 12.8 0.0 0.31 10.7 0.0 2.0 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_28 PF13521.6 CBK22573.2 - 0.081 13.2 0.1 0.23 11.7 0.0 1.8 2 0 0 2 2 1 0 AAA domain NTPase_1 PF03266.15 CBK22573.2 - 0.12 12.2 2.6 2.6 7.9 0.1 3.3 3 1 0 3 3 3 0 NTPase AAA_11 PF13086.6 CBK22573.2 - 0.17 11.6 0.8 1.4 8.7 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 CBK22573.2 - 0.23 11.1 0.7 0.56 9.9 0.7 1.6 1 0 0 1 1 1 0 AAA domain FliT PF05400.13 CBK22573.2 - 0.82 10.5 3.4 0.7 10.7 0.5 2.4 2 1 0 2 2 2 0 Flagellar protein FliT MMS19_C PF12460.8 CBK22574.2 - 0.074 12.1 0.0 0.15 11.1 0.0 1.5 1 0 0 1 1 1 0 RNAPII transcription regulator C-terminal HEAT PF02985.22 CBK22575.2 - 3.1e-09 36.3 3.0 2.8 8.4 0.0 6.6 6 0 0 6 6 6 3 HEAT repeat HEAT_EZ PF13513.6 CBK22575.2 - 7.6e-06 26.3 0.7 0.66 10.6 0.0 5.4 6 0 0 6 6 6 1 HEAT-like repeat Importin_rep_4 PF18808.1 CBK22575.2 - 1.1e-05 25.6 0.2 0.0001 22.5 0.0 2.8 3 0 0 3 3 3 1 Importin repeat HEAT_2 PF13646.6 CBK22575.2 - 0.00024 21.4 0.4 21 5.6 0.0 5.4 3 1 3 6 6 6 0 HEAT repeats Cnd1 PF12717.7 CBK22575.2 - 0.0092 16.0 4.6 15 5.6 0.2 4.4 3 2 2 5 5 5 2 non-SMC mitotic condensation complex subunit 1 MMS19_C PF12460.8 CBK22575.2 - 0.012 14.8 4.5 0.082 12.0 0.0 3.6 3 1 0 4 4 4 0 RNAPII transcription regulator C-terminal RTP1_C1 PF10363.9 CBK22575.2 - 0.013 15.7 0.7 0.13 12.4 0.2 2.9 3 1 0 3 3 3 0 Required for nuclear transport of RNA pol II C-terminus 1 RICTOR_V PF14668.6 CBK22575.2 - 0.046 14.0 0.9 1.3 9.3 0.1 3.5 4 0 0 4 4 4 0 Rapamycin-insensitive companion of mTOR, domain 5 DUF3385 PF11865.8 CBK22575.2 - 0.42 10.5 7.0 1.1 9.2 1.4 2.9 2 1 0 3 3 3 0 Domain of unknown function (DUF3385) DUF760 PF05542.11 CBK22575.2 - 0.89 10.0 4.2 11 6.4 1.1 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF760) DNA_pol_phi PF04931.13 CBK22576.2 - 4.5e-29 101.2 34.2 5.7e-29 100.8 34.2 1.1 1 0 0 1 1 1 1 DNA polymerase phi Q_salvage PF10343.9 CBK22576.2 - 0.023 14.3 1.8 0.049 13.2 1.1 1.8 1 1 1 2 2 2 0 Potential Queuosine, Q, salvage protein family CPSF100_C PF13299.6 CBK22576.2 - 0.079 13.1 11.1 0.24 11.6 11.1 1.9 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal DUF913 PF06025.12 CBK22576.2 - 0.084 11.8 4.5 0.12 11.3 4.5 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) DUF4746 PF15928.5 CBK22576.2 - 0.13 11.6 18.7 0.25 10.7 18.7 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) DUF3330 PF11809.8 CBK22576.2 - 0.14 12.2 1.4 2.3 8.3 0.0 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF3330) RR_TM4-6 PF06459.12 CBK22576.2 - 0.43 10.4 20.2 0.034 14.0 14.5 2.0 2 1 0 2 2 2 0 Ryanodine Receptor TM 4-6 DUF4471 PF14740.6 CBK22576.2 - 0.78 8.9 8.4 1.8 7.8 8.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4471) DDHD PF02862.17 CBK22576.2 - 0.95 9.6 8.0 2.3 8.3 7.5 1.9 1 1 0 1 1 1 0 DDHD domain Paf1 PF03985.13 CBK22576.2 - 1.1 8.1 31.2 2.4 7.1 31.2 1.5 1 0 0 1 1 1 0 Paf1 RNA_pol_Rpc4 PF05132.14 CBK22576.2 - 1.4 9.4 8.6 3.3 8.1 8.6 1.7 1 0 0 1 1 1 0 RNA polymerase III RPC4 Zip PF02535.22 CBK22576.2 - 3.2 6.9 10.1 5.3 6.2 10.1 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter SLC12 PF03522.15 CBK22576.2 - 4.4 6.2 10.1 16 4.4 9.4 2.0 2 0 0 2 2 2 0 Solute carrier family 12 SDA1 PF05285.12 CBK22576.2 - 9.1 5.6 42.4 19 4.5 42.4 1.6 1 1 0 1 1 1 0 SDA1 DNA_pol_phi PF04931.13 CBK22577.2 - 3.1e-38 131.5 5.0 1.7e-37 129.0 3.2 2.4 2 1 0 2 2 2 1 DNA polymerase phi DUF4062 PF13271.6 CBK22578.2 - 0.094 13.1 0.1 0.13 12.7 0.1 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4062) Ribosomal_L28e PF01778.17 CBK22579.2 - 8.7e-38 129.6 2.9 8.7e-38 129.6 2.9 1.9 2 0 0 2 2 2 1 Ribosomal L28e protein family Mak16 PF04874.14 CBK22579.2 - 1.5e-21 76.9 18.8 1.5e-21 76.9 18.8 2.2 2 1 0 2 2 2 1 Mak16 protein C-terminal region Exonuc_VII_L PF02601.15 CBK22579.2 - 0.012 15.2 1.2 0.014 15.0 1.2 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit LMBR1 PF04791.16 CBK22579.2 - 1.5 7.6 3.2 1.8 7.4 3.2 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF2207 PF09972.9 CBK22579.2 - 3.1 6.4 7.3 2.8 6.6 6.1 1.4 1 1 1 2 2 2 0 Predicted membrane protein (DUF2207) DUF4168 PF13767.6 CBK22579.2 - 4.1 8.7 7.8 2.1 9.6 3.5 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4168) Pkinase PF00069.25 CBK22581.2 - 3.6e-76 256.0 0.0 4.8e-76 255.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBK22581.2 - 2.4e-40 138.5 0.0 3.5e-40 137.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CBK22581.2 - 3.9e-05 23.1 0.0 0.0001 21.7 0.0 1.8 1 1 1 2 2 2 1 Kinase-like PH PF00169.29 CBK22581.2 - 0.0011 19.4 0.0 0.0022 18.5 0.0 1.5 1 0 0 1 1 1 1 PH domain Pkinase_fungal PF17667.1 CBK22581.2 - 0.0052 15.6 0.2 0.016 14.0 0.0 1.7 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 CBK22581.2 - 0.051 13.5 0.0 4.9 7.0 0.0 2.4 1 1 1 2 2 2 0 Phosphotransferase enzyme family GST_N PF02798.20 CBK22582.2 - 5.4e-05 23.5 0.0 0.00011 22.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 CBK22582.2 - 0.00076 19.8 0.0 0.0014 19.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_4 PF17172.4 CBK22582.2 - 0.12 13.2 0.0 0.21 12.3 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase N-terminal domain YdjC PF04794.12 CBK22583.2 - 4.5e-26 92.3 0.0 5e-26 92.1 0.0 1.0 1 0 0 1 1 1 1 YdjC-like protein Glycos_transf_1 PF00534.20 CBK22584.2 - 7.9e-12 45.0 0.0 1.1e-11 44.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 CBK22584.2 - 9.6e-05 22.7 0.0 0.00012 22.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 CBK22584.2 - 0.0001 22.7 0.0 0.00013 22.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferases group 1 HSP20 PF00011.21 CBK22585.2 - 2.2e-17 63.0 0.2 2.8e-17 62.7 0.2 1.2 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 CBK22585.2 - 1.7e-06 27.5 0.2 8.3e-06 25.3 0.2 2.0 1 1 0 1 1 1 1 HSP20-like domain found in ArsA GvpH PF05455.11 CBK22585.2 - 0.027 14.6 0.3 0.051 13.6 0.2 1.6 1 1 1 2 2 2 0 GvpH ADK PF00406.22 CBK22586.2 - 8.8e-30 103.8 0.0 1.8e-29 102.8 0.0 1.5 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 CBK22586.2 - 5.7e-19 68.9 0.0 1.6e-18 67.5 0.0 1.7 2 0 0 2 2 2 1 AAA domain Tub PF01167.18 CBK22586.2 - 2.1e-14 53.8 0.0 3.9e-14 53.0 0.0 1.3 1 0 0 1 1 1 1 Tub family AAA_18 PF13238.6 CBK22586.2 - 2.4e-08 34.6 0.0 7.6e-08 33.0 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 CBK22586.2 - 0.00078 19.6 0.0 0.0017 18.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain BTB PF00651.31 CBK22586.2 - 0.034 14.4 0.0 0.11 12.7 0.0 1.9 1 1 0 1 1 1 0 BTB/POZ domain AAA_28 PF13521.6 CBK22586.2 - 0.18 12.1 0.0 0.32 11.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain GCD14 PF08704.10 CBK22587.2 - 7.8e-76 255.0 0.6 1.3e-70 237.9 0.1 2.1 1 1 1 2 2 2 2 tRNA methyltransferase complex GCD14 subunit Methyltransf_31 PF13847.6 CBK22587.2 - 2.1e-07 30.8 0.0 3.9e-07 30.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain GCD14_N PF14801.6 CBK22587.2 - 6.5e-07 29.1 0.0 1.5e-06 27.9 0.0 1.6 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit N-term Methyltransf_24 PF13578.6 CBK22587.2 - 0.00014 22.9 0.1 0.00064 20.7 0.0 2.0 1 1 1 2 2 2 1 Methyltransferase domain PCMT PF01135.19 CBK22587.2 - 0.0015 18.3 0.0 0.0026 17.5 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) PrmA PF06325.13 CBK22587.2 - 0.033 13.6 0.0 0.083 12.3 0.0 1.7 1 1 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.6 CBK22587.2 - 0.042 14.5 0.0 0.1 13.3 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.14 CBK22587.2 - 0.046 13.3 0.0 0.17 11.4 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase small domain Fibrillarin PF01269.17 CBK22587.2 - 0.05 12.7 0.0 0.65 9.1 0.0 2.1 1 1 0 1 1 1 0 Fibrillarin CDC45 PF02724.14 CBK22587.2 - 0.15 10.3 6.7 0.19 10.0 6.7 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF4045 PF13254.6 CBK22587.2 - 0.16 11.6 12.4 0.21 11.2 12.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) Zip PF02535.22 CBK22587.2 - 1.3 8.2 3.5 1.8 7.7 3.5 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter DUF913 PF06025.12 CBK22587.2 - 1.6 7.6 6.1 2.3 7.1 6.1 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Presenilin PF01080.17 CBK22587.2 - 7.1 5.3 14.6 10 4.8 14.6 1.2 1 0 0 1 1 1 0 Presenilin Spore_coat_CotO PF14153.6 CBK22587.2 - 9.3 6.1 17.2 15 5.4 17.2 1.3 1 0 0 1 1 1 0 Spore coat protein CotO NUDIX PF00293.28 CBK22588.2 - 4.8e-08 33.1 0.0 6.6e-08 32.7 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain LRR_5 PF13306.6 CBK22589.2 - 5.6e-09 36.0 2.0 0.00011 22.2 0.1 3.9 1 1 1 3 3 3 3 BspA type Leucine rich repeat region (6 copies) Transcrip_reg PF01709.20 CBK22589.2 - 0.17 11.3 0.8 0.29 10.5 0.8 1.3 1 0 0 1 1 1 0 Transcriptional regulator GDC-P PF02347.16 CBK22590.2 - 9.7e-178 591.4 1.3 4.6e-170 566.1 0.0 2.8 3 1 0 3 3 3 2 Glycine cleavage system P-protein Aminotran_5 PF00266.19 CBK22590.2 - 1.5e-07 30.8 1.1 0.00012 21.2 0.0 2.4 2 1 0 2 2 2 2 Aminotransferase class-V Beta_elim_lyase PF01212.21 CBK22590.2 - 0.0006 19.2 0.1 0.0018 17.6 0.1 1.8 1 0 0 1 1 1 1 Beta-eliminating lyase DEAD PF00270.29 CBK22591.2 - 4e-36 124.4 0.1 3.8e-35 121.2 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CBK22591.2 - 4e-14 52.9 0.2 2.1e-12 47.4 0.0 3.3 3 1 2 5 5 5 1 Helicase conserved C-terminal domain ResIII PF04851.15 CBK22591.2 - 2.6e-09 37.3 0.0 1.8e-08 34.6 0.0 2.0 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit zf-HIT PF04438.16 CBK22592.2 - 1.4e-07 31.3 1.6 1.7e-07 31.0 1.6 1.2 1 0 0 1 1 1 1 HIT zinc finger Toprim_C_rpt PF13368.6 CBK22592.2 - 0.0013 18.7 0.0 0.0016 18.4 0.0 1.3 1 0 0 1 1 1 1 Topoisomerase C-terminal repeat DUF2116 PF09889.9 CBK22592.2 - 0.035 14.1 4.8 0.12 12.4 4.8 1.7 1 1 0 1 1 1 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) TM1506 PF08973.10 CBK22592.2 - 0.13 11.9 0.5 0.17 11.6 0.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1893) MCM PF00493.23 CBK22593.2 - 1.7e-94 315.1 0.0 4.5e-94 313.7 0.0 1.7 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 CBK22593.2 - 1.7e-35 121.6 2.3 3e-35 120.8 2.3 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 CBK22593.2 - 1.6e-25 89.3 0.8 3e-25 88.4 0.8 1.5 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 CBK22593.2 - 6.3e-16 58.9 0.2 1.8e-15 57.4 0.2 1.8 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 CBK22593.2 - 9.7e-09 34.9 0.1 1.7e-05 24.3 0.0 2.3 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 CBK22593.2 - 1.3e-06 28.4 0.1 8.8e-06 25.8 0.0 2.5 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 CBK22593.2 - 0.0026 17.6 0.0 0.0068 16.3 0.0 1.7 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 CBK22593.2 - 0.0099 16.3 0.7 0.61 10.5 0.0 2.9 2 1 1 3 3 3 1 AAA ATPase domain TIP49_C PF17856.1 CBK22593.2 - 0.011 15.9 0.2 0.035 14.3 0.2 1.8 1 0 0 1 1 1 0 TIP49 AAA-lid domain SIR2 PF02146.17 CBK22593.2 - 0.016 15.2 0.2 0.03 14.3 0.2 1.4 1 0 0 1 1 1 0 Sir2 family Zn-ribbon_8 PF09723.10 CBK22593.2 - 0.021 14.9 3.0 0.051 13.7 3.0 1.6 1 0 0 1 1 1 0 Zinc ribbon domain AAA PF00004.29 CBK22593.2 - 0.034 14.6 0.0 0.12 12.8 0.0 2.0 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 CBK22593.2 - 0.037 13.7 0.0 13 5.5 0.0 2.5 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_lid_2 PF17863.1 CBK22593.2 - 0.072 12.9 0.2 0.18 11.7 0.2 1.6 1 0 0 1 1 1 0 AAA lid domain PhnA_Zn_Ribbon PF08274.12 CBK22593.2 - 0.55 10.2 2.3 28 4.8 0.4 2.4 2 0 0 2 2 2 0 PhnA Zinc-Ribbon Ribosomal_L23 PF00276.20 CBK22594.2 - 1.1e-15 57.8 2.6 3.9e-15 56.0 2.6 1.7 1 1 0 1 1 1 1 Ribosomal protein L23 IL31 PF15209.6 CBK22594.2 - 0.049 13.4 0.2 0.059 13.2 0.2 1.1 1 0 0 1 1 1 0 Interleukin 31 RabGAP-TBC PF00566.18 CBK22596.2 - 7.8e-28 97.6 2.8 8.5e-28 97.5 1.2 1.9 2 0 0 2 2 2 1 Rab-GTPase-TBC domain PIG-L PF02585.17 CBK22596.2 - 3e-20 73.2 0.3 9.6e-20 71.6 0.0 1.9 2 0 0 2 2 2 1 GlcNAc-PI de-N-acetylase DUF1515 PF07439.11 CBK22596.2 - 0.62 10.1 4.0 1.6 8.8 0.5 2.9 3 1 0 3 3 3 0 Protein of unknown function (DUF1515) DnaJ PF00226.31 CBK22597.2 - 3.2e-28 97.6 2.9 4.7e-28 97.1 2.9 1.3 1 0 0 1 1 1 1 DnaJ domain RPT PF13446.6 CBK22597.2 - 0.16 11.9 0.0 0.48 10.4 0.0 1.7 2 0 0 2 2 2 0 A repeated domain in UCH-protein Tmemb_185A PF10269.9 CBK22597.2 - 0.22 11.1 31.6 0.032 13.9 26.6 2.1 2 1 0 2 2 2 0 Transmembrane Fragile-X-F protein Aldo_ket_red PF00248.21 CBK22598.2 - 6.3e-47 160.2 0.0 9e-47 159.7 0.0 1.2 1 0 0 1 1 1 1 Aldo/keto reductase family Slx4 PF09494.10 CBK22598.2 - 0.031 14.2 0.0 0.069 13.1 0.0 1.6 1 0 0 1 1 1 0 Slx4 endonuclease LRR_8 PF13855.6 CBK22599.2 - 0.018 14.8 0.2 0.9 9.4 0.0 3.2 2 2 0 2 2 2 0 Leucine rich repeat LRR_4 PF12799.7 CBK22599.2 - 0.019 15.4 4.7 12 6.4 0.2 4.3 1 1 3 5 5 5 0 Leucine Rich repeats (2 copies) Sialidase PF02973.16 CBK22599.2 - 0.025 14.1 0.0 0.57 9.6 0.0 2.6 1 1 1 2 2 2 0 Sialidase, N-terminal domain DNA_pol_B_2 PF03175.13 CBK22600.2 - 9.5e-18 64.3 11.9 3.3e-15 55.9 5.3 2.6 2 1 0 3 3 3 2 DNA polymerase type B, organellar and viral ID PF18543.1 CBK22600.2 - 0.16 12.0 1.2 2.8 8.0 0.0 2.5 2 0 0 2 2 2 0 Intracellular delivery domain DNA_pol_B_2 PF03175.13 CBK22601.2 - 1.7e-16 60.2 11.6 1.8e-13 50.2 6.7 2.6 2 1 0 2 2 2 2 DNA polymerase type B, organellar and viral Ifi-6-16 PF06140.13 CBK22602.2 - 4.1e-06 26.6 27.9 4.1e-06 26.6 27.9 2.2 1 1 1 2 2 2 1 Interferon-induced 6-16 family ubiquitin PF00240.23 CBK22603.2 - 3.1e-10 39.6 0.2 3.3e-10 39.6 0.2 1.0 1 0 0 1 1 1 1 Ubiquitin family Ubiquitin_5 PF18037.1 CBK22603.2 - 0.046 14.1 0.1 0.054 13.9 0.1 1.1 1 0 0 1 1 1 0 Ubiquitin-like domain Glucosamine_iso PF01182.20 CBK22604.2 - 6.1e-19 68.8 0.0 6.6e-19 68.7 0.0 1.0 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase RNase_Zc3h12a PF11977.8 CBK22605.2 - 3.8e-05 23.5 0.2 0.00013 21.8 0.0 1.9 2 0 0 2 2 2 1 Zc3h12a-like Ribonuclease NYN domain Phage_glycop_gL PF11108.8 CBK22605.2 - 0.035 14.1 0.6 0.087 12.9 0.1 1.9 2 0 0 2 2 2 0 Viral glycoprotein L DUF1980 PF09323.10 CBK22605.2 - 0.17 11.8 2.4 0.4 10.6 2.3 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF1980) RRM_1 PF00076.22 CBK22606.2 - 2.1e-18 65.9 0.1 3.4e-18 65.2 0.1 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 CBK22606.2 - 9.4e-06 25.2 0.0 1.1e-05 25.0 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) OB_RNB PF08206.11 CBK22606.2 - 0.023 14.4 0.1 0.053 13.2 0.1 1.6 1 0 0 1 1 1 0 Ribonuclease B OB domain RRM_occluded PF16842.5 CBK22606.2 - 0.034 14.0 0.0 0.053 13.4 0.0 1.5 1 1 0 1 1 1 0 Occluded RNA-recognition motif Limkain-b1 PF11608.8 CBK22606.2 - 0.15 12.1 0.0 0.22 11.6 0.0 1.3 1 0 0 1 1 1 0 Limkain b1 DEAD PF00270.29 CBK22607.2 - 3.1e-42 144.3 0.0 5.3e-42 143.6 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CBK22607.2 - 1.4e-33 115.5 0.0 2.3e-32 111.6 0.0 2.6 3 0 0 3 3 3 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 CBK22607.2 - 0.078 13.2 0.1 0.2 11.9 0.1 1.8 1 1 0 1 1 1 0 AAA domain EMP24_GP25L PF01105.24 CBK22608.2 - 0.00027 20.9 3.1 0.0017 18.3 3.1 2.1 1 1 0 1 1 1 1 emp24/gp25L/p24 family/GOLD GOLD_2 PF13897.6 CBK22608.2 - 0.00047 20.7 8.0 0.22 12.0 0.0 3.3 3 0 0 3 3 3 2 Golgi-dynamics membrane-trafficking APG6_N PF17675.1 CBK22608.2 - 0.00072 20.1 12.2 0.0014 19.1 12.2 1.4 1 0 0 1 1 1 1 Apg6 coiled-coil region Spc7 PF08317.11 CBK22608.2 - 0.001 18.0 11.0 0.0018 17.2 11.0 1.3 1 0 0 1 1 1 1 Spc7 kinetochore protein Golgin_A5 PF09787.9 CBK22608.2 - 0.0034 16.9 9.8 0.0049 16.4 9.8 1.1 1 0 0 1 1 1 1 Golgin subfamily A member 5 GAS PF13851.6 CBK22608.2 - 0.0042 16.5 9.6 0.0061 15.9 9.6 1.2 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding BRE1 PF08647.11 CBK22608.2 - 0.0043 17.1 10.7 0.0073 16.4 10.7 1.3 1 0 0 1 1 1 1 BRE1 E3 ubiquitin ligase Phlebovirus_NSM PF07246.11 CBK22608.2 - 0.0055 16.1 2.5 0.0088 15.5 2.5 1.3 1 0 0 1 1 1 1 Phlebovirus nonstructural protein NS-M DUF812 PF05667.11 CBK22608.2 - 0.0063 15.5 5.2 0.009 15.0 5.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF812) FapA PF03961.13 CBK22608.2 - 0.0079 14.8 2.5 0.011 14.4 2.5 1.1 1 0 0 1 1 1 1 Flagellar Assembly Protein A Laminin_II PF06009.12 CBK22608.2 - 0.017 15.1 5.0 0.03 14.4 3.3 1.9 1 1 1 2 2 2 0 Laminin Domain II DUF4200 PF13863.6 CBK22608.2 - 0.019 15.3 9.4 0.035 14.5 9.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) DUF919 PF06034.11 CBK22608.2 - 0.022 14.6 6.0 0.056 13.3 6.0 1.7 1 1 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF919) DUF848 PF05852.11 CBK22608.2 - 0.029 14.5 6.4 0.052 13.6 6.4 1.4 1 0 0 1 1 1 0 Gammaherpesvirus protein of unknown function (DUF848) Rab5-bind PF09311.11 CBK22608.2 - 0.035 13.5 11.2 0.05 13.0 11.2 1.2 1 0 0 1 1 1 0 Rabaptin-like protein DUF4988 PF16378.5 CBK22608.2 - 0.042 13.5 0.1 0.11 12.2 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function AAA_13 PF13166.6 CBK22608.2 - 0.042 12.5 6.1 0.058 12.0 6.1 1.1 1 0 0 1 1 1 0 AAA domain COG5 PF10392.9 CBK22608.2 - 0.054 13.7 2.3 0.079 13.1 2.3 1.2 1 0 0 1 1 1 0 Golgi transport complex subunit 5 DUF3450 PF11932.8 CBK22608.2 - 0.059 12.7 5.5 0.1 11.9 5.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) ADIP PF11559.8 CBK22608.2 - 0.08 13.0 6.8 0.12 12.4 6.8 1.2 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding MscS_porin PF12795.7 CBK22608.2 - 0.098 12.2 8.9 0.15 11.6 8.9 1.1 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain APG17 PF04108.12 CBK22608.2 - 0.11 11.6 6.5 0.15 11.1 6.5 1.1 1 0 0 1 1 1 0 Autophagy protein Apg17 Atg14 PF10186.9 CBK22608.2 - 0.12 11.5 7.9 0.17 11.0 7.9 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF724 PF05266.14 CBK22608.2 - 0.12 12.2 8.5 0.21 11.4 8.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF724) YscO PF07321.12 CBK22608.2 - 0.14 12.1 11.6 0.98 9.4 11.7 2.0 1 1 0 1 1 1 0 Type III secretion protein YscO CENP-Q PF13094.6 CBK22608.2 - 0.18 12.0 6.1 0.31 11.2 6.1 1.3 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit TMPIT PF07851.13 CBK22608.2 - 0.18 11.0 7.8 0.26 10.5 7.8 1.2 1 0 0 1 1 1 0 TMPIT-like protein HIP1_clath_bdg PF16515.5 CBK22608.2 - 0.21 12.2 9.8 0.41 11.3 9.8 1.4 1 0 0 1 1 1 0 Clathrin-binding domain of Huntingtin-interacting protein 1 DUF2203 PF09969.9 CBK22608.2 - 0.24 12.1 3.7 0.43 11.3 3.7 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) DUF2730 PF10805.8 CBK22608.2 - 0.26 11.4 5.7 0.19 11.9 3.8 1.7 2 0 0 2 2 1 0 Protein of unknown function (DUF2730) Bcr-Abl_Oligo PF09036.10 CBK22608.2 - 0.28 11.2 3.6 0.25 11.4 0.7 2.2 1 1 1 2 2 2 0 Bcr-Abl oncoprotein oligomerisation domain Fib_alpha PF08702.10 CBK22608.2 - 0.46 10.7 9.8 5 7.3 9.8 2.0 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family V_ATPase_I PF01496.19 CBK22608.2 - 0.59 8.0 4.7 0.77 7.6 4.7 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DivIC PF04977.15 CBK22608.2 - 1.6 8.6 11.6 2.7 7.8 3.2 2.5 1 1 1 2 2 2 0 Septum formation initiator DUF2408 PF10303.9 CBK22608.2 - 1.6 9.3 9.2 4.1 8.0 9.2 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2408) DUF16 PF01519.16 CBK22608.2 - 1.8 9.1 7.7 9.7 6.7 7.7 2.1 1 1 0 1 1 1 0 Protein of unknown function DUF16 CC2-LZ PF16516.5 CBK22608.2 - 1.8 9.0 12.1 0.8 10.1 5.9 2.2 1 1 1 2 2 2 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator ZapB PF06005.12 CBK22608.2 - 3.7 8.0 13.4 37 4.8 13.4 2.3 1 1 0 1 1 1 0 Cell division protein ZapB XhlA PF10779.9 CBK22608.2 - 4.1 7.7 10.1 3.9 7.7 6.6 2.2 1 1 1 2 2 2 0 Haemolysin XhlA Prefoldin_2 PF01920.20 CBK22608.2 - 4.3 7.3 15.4 8.3 6.4 3.9 2.4 1 1 1 2 2 2 0 Prefoldin subunit Yippee-Mis18 PF03226.14 CBK22609.2 - 3.1e-05 24.1 0.0 4e-05 23.8 0.0 1.3 1 1 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Rsm1 PF08600.10 CBK22609.2 - 0.095 12.9 0.1 0.13 12.4 0.1 1.3 1 0 0 1 1 1 0 Rsm1-like TPT PF03151.16 CBK22610.2 - 8.2e-15 54.9 6.0 9.4e-15 54.7 6.0 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 CBK22610.2 - 1.7e-06 28.2 4.9 2e-06 28.0 4.9 1.1 1 0 0 1 1 1 1 EamA-like transporter family TPT PF03151.16 CBK22611.2 - 5e-23 81.9 9.3 7.2e-23 81.4 9.3 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family Homeobox_KN PF05920.11 CBK22611.2 - 7.2e-17 61.0 1.3 1.1e-16 60.4 0.3 1.9 2 0 0 2 2 2 1 Homeobox KN domain Homeodomain PF00046.29 CBK22611.2 - 3.8e-07 29.8 2.0 5.2e-07 29.4 0.5 2.0 2 0 0 2 2 2 1 Homeodomain EamA PF00892.20 CBK22611.2 - 0.0018 18.5 15.7 0.0027 17.9 15.7 1.3 1 0 0 1 1 1 1 EamA-like transporter family zf-H2C2_2 PF13465.6 CBK22612.2 - 5.2e-28 96.2 29.9 2.2e-07 31.0 0.3 6.3 6 0 0 6 6 6 5 Zinc-finger double domain zf-H2C2_5 PF13909.6 CBK22612.2 - 2.6e-20 71.8 30.6 8.4e-06 25.4 1.1 5.9 6 0 0 6 6 6 5 C2H2-type zinc-finger domain zf-C2H2 PF00096.26 CBK22612.2 - 4e-17 61.6 37.0 0.0001 22.6 0.2 6.1 6 0 0 6 6 6 5 Zinc finger, C2H2 type zf-C2H2_aberr PF17017.5 CBK22612.2 - 2.7e-05 24.4 19.8 0.0024 18.0 1.1 3.9 3 1 0 4 4 4 2 Aberrant zinc-finger zf-C2H2_4 PF13894.6 CBK22612.2 - 0.00088 19.9 42.3 0.37 11.7 1.0 6.3 6 0 0 6 6 6 5 C2H2-type zinc finger OrsD PF12013.8 CBK22612.2 - 0.0056 17.1 27.8 1.9 9.0 0.7 5.8 5 1 1 6 6 6 4 Orsellinic acid/F9775 biosynthesis cluster protein D DUF1936 PF09151.10 CBK22612.2 - 3.3 7.7 19.9 3 7.8 0.7 6.0 6 0 0 6 6 6 0 Domain of unknown function (DUF1936) RNA_pol_I_A49 PF06870.12 CBK22614.2 - 4.1e-09 35.8 4.0 5.3e-09 35.4 4.0 1.1 1 0 0 1 1 1 1 A49-like RNA polymerase I associated factor HMG_box PF00505.19 CBK22616.2 - 7.1e-50 167.3 26.7 8.6e-27 93.4 6.9 2.8 2 1 0 2 2 2 2 HMG (high mobility group) box HMG_box_2 PF09011.10 CBK22616.2 - 1.4e-27 96.0 27.6 2.8e-14 53.5 6.9 2.9 2 1 1 3 3 3 2 HMG-box domain CHDNT PF08073.12 CBK22616.2 - 5.2e-08 32.7 0.1 0.0033 17.4 0.0 2.5 2 0 0 2 2 2 2 CHDNT (NUC034) domain MlaC PF05494.12 CBK22616.2 - 2.4e-05 24.1 3.2 0.061 13.1 0.5 2.3 1 1 0 2 2 2 2 MlaC protein YABBY PF04690.13 CBK22616.2 - 0.00086 19.9 2.6 0.00086 19.9 2.6 3.1 1 1 2 3 3 3 2 YABBY protein Ccdc124 PF06244.12 CBK22616.2 - 0.015 15.8 1.4 0.015 15.8 1.4 3.7 1 1 2 3 3 3 0 Coiled-coil domain-containing protein 124 /Oxs1 DUF5535 PF17687.1 CBK22616.2 - 0.1 12.8 1.8 1.2 9.3 0.5 2.2 1 1 1 2 2 2 0 Family of unknown function (DUF5535) KfrA_N PF11740.8 CBK22616.2 - 0.31 11.7 4.5 2.3 8.9 1.1 2.4 2 1 0 2 2 2 0 Plasmid replication region DNA-binding N-term CPSase_L_D2 PF02786.17 CBK22617.2 - 2e-72 243.1 0.0 3.3e-72 242.4 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 CBK22617.2 - 6.6e-44 149.0 0.0 1.6e-43 147.7 0.0 1.7 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 CBK22617.2 - 1.9e-36 124.4 0.0 4.2e-36 123.3 0.0 1.6 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.22 CBK22617.2 - 4.5e-18 64.9 0.2 9.6e-18 63.8 0.2 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme PCC_BT PF18140.1 CBK22617.2 - 1.6e-10 41.4 0.1 1.4e-05 25.4 0.0 2.5 1 1 1 2 2 2 2 Propionyl-coenzyme A carboxylase BT domain Biotin_lipoyl_2 PF13533.6 CBK22617.2 - 2.9e-08 33.4 0.1 1.6e-07 31.1 0.0 2.1 1 1 1 2 2 2 1 Biotin-lipoyl like Dala_Dala_lig_C PF07478.13 CBK22617.2 - 8e-08 32.1 0.1 3.5e-07 30.0 0.0 2.0 1 1 1 2 2 2 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 CBK22617.2 - 2.5e-05 23.9 0.0 5.3e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain DUF2118 PF09891.9 CBK22617.2 - 0.0022 18.0 0.0 0.0054 16.7 0.0 1.6 1 0 0 1 1 1 1 Uncharacterized protein conserved in archaea (DUF2118) GCV_H PF01597.19 CBK22617.2 - 0.003 17.5 0.1 0.011 15.6 0.1 2.0 1 0 0 1 1 1 1 Glycine cleavage H-protein PTS_EIIA_1 PF00358.20 CBK22617.2 - 0.0036 17.1 0.0 0.01 15.6 0.0 1.8 1 0 0 1 1 1 1 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 Peptidase_M23 PF01551.22 CBK22617.2 - 0.026 14.7 0.1 0.29 11.4 0.0 2.3 2 0 0 2 2 2 0 Peptidase family M23 RnfC_N PF13375.6 CBK22617.2 - 0.05 13.6 0.0 0.12 12.3 0.0 1.6 1 0 0 1 1 1 0 RnfC Barrel sandwich hybrid domain PYNP_C PF07831.13 CBK22617.2 - 0.064 12.9 0.0 0.2 11.3 0.0 1.8 1 0 0 1 1 1 0 Pyrimidine nucleoside phosphorylase C-terminal domain HlyD_D23 PF16576.5 CBK22617.2 - 0.092 11.9 0.0 0.19 10.9 0.0 1.5 1 0 0 1 1 1 0 Barrel-sandwich domain of CusB or HlyD membrane-fusion HlyD_3 PF13437.6 CBK22617.2 - 0.12 13.1 0.2 0.49 11.1 0.1 2.2 2 1 0 2 2 2 0 HlyD family secretion protein PX PF00787.24 CBK22618.2 - 8.9e-23 80.4 0.2 2.2e-22 79.1 0.2 1.7 1 0 0 1 1 1 1 PX domain Vps5 PF09325.10 CBK22618.2 - 4.8e-20 72.1 3.1 4.8e-20 72.1 3.1 1.7 2 0 0 2 2 2 1 Vps5 C terminal like SDA1 PF05285.12 CBK22618.2 - 5.9e-05 22.6 36.1 0.00014 21.4 36.1 1.7 1 0 0 1 1 1 1 SDA1 Syntaxin_2 PF14523.6 CBK22618.2 - 0.039 14.3 4.1 0.61 10.5 0.2 3.3 1 1 1 2 2 2 0 Syntaxin-like protein Tape_meas_lam_C PF09718.10 CBK22618.2 - 0.048 13.8 0.8 24 5.1 0.1 3.8 3 0 0 3 3 3 0 Lambda phage tail tape-measure protein (Tape_meas_lam_C) DUF948 PF06103.11 CBK22618.2 - 0.12 12.6 2.0 6.6 7.1 0.0 2.9 1 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) BLOC1_2 PF10046.9 CBK22618.2 - 0.25 11.7 4.8 0.53 10.6 0.6 3.2 2 2 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Ribosomal_L1 PF00687.21 CBK22619.2 - 5.9e-44 150.3 5.8 8.2e-44 149.8 5.8 1.1 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family zf-TRAF_2 PF15965.5 CBK22619.2 - 0.091 13.2 1.5 0.48 10.9 0.5 2.2 2 0 0 2 2 2 0 TRAF-like zinc-finger E1-E2_ATPase PF00122.20 CBK22620.2 - 9.5e-19 67.6 0.0 1.4e-18 67.1 0.0 1.2 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_N PF00690.26 CBK22620.2 - 0.00017 21.2 0.0 0.00024 20.7 0.0 1.2 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus GTP_EFTU PF00009.27 CBK22621.2 - 2.6e-54 183.7 0.0 3.7e-54 183.2 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 CBK22621.2 - 3.4e-40 136.8 0.0 8.2e-40 135.6 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 CBK22621.2 - 9.8e-08 32.3 0.0 2.7e-07 30.9 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 CBK22621.2 - 0.00011 22.2 0.1 0.0023 18.0 0.1 2.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase HSP90 PF00183.18 CBK22622.2 - 2.2e-198 660.4 53.9 2.2e-198 660.4 53.9 2.1 1 1 1 2 2 2 1 Hsp90 protein HATPase_c PF02518.26 CBK22622.2 - 3.7e-11 43.5 0.2 8e-11 42.4 0.2 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 CBK22622.2 - 4.3e-08 33.1 0.2 4.3e-08 33.1 0.2 2.8 3 0 0 3 3 3 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Diphthamide_syn PF01866.17 CBK22623.2 - 3.9e-62 210.4 0.1 4.7e-62 210.1 0.1 1.1 1 0 0 1 1 1 1 Putative diphthamide synthesis protein SPASM PF13186.6 CBK22623.2 - 0.01 16.4 1.9 0.2 12.2 0.8 2.8 2 0 0 2 2 2 0 Iron-sulfur cluster-binding domain Imm26 PF15428.6 CBK22624.2 - 0.016 15.5 0.7 0.016 15.5 0.7 1.8 2 1 0 2 2 2 0 Immunity protein 26 BRO1 PF03097.18 CBK22625.2 - 1.5e-21 76.7 14.8 3.8e-21 75.4 14.8 1.7 1 1 0 1 1 1 1 BRO1-like domain RasGAP_C PF03836.15 CBK22625.2 - 0.0026 17.9 9.7 0.38 10.9 0.0 4.1 4 0 0 4 4 4 2 RasGAP C-terminus Baculo_PEP_C PF04513.12 CBK22625.2 - 0.037 14.1 9.9 2.2 8.3 0.2 4.9 5 1 0 5 5 5 0 Baculovirus polyhedron envelope protein, PEP, C terminus Med9 PF07544.13 CBK22625.2 - 0.059 13.5 2.8 1.3 9.2 0.0 3.6 4 0 0 4 4 4 0 RNA polymerase II transcription mediator complex subunit 9 BLOC1_2 PF10046.9 CBK22625.2 - 0.18 12.1 11.4 2.1 8.7 0.3 5.2 5 1 0 6 6 6 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 SF-assemblin PF06705.11 CBK22625.2 - 0.57 9.5 13.7 2.5 7.4 0.6 3.6 3 1 1 4 4 4 0 SF-assemblin/beta giardin DUF1664 PF07889.12 CBK22625.2 - 2.6 8.1 5.0 8.3 6.5 0.4 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) THOC7 PF05615.13 CBK22625.2 - 3.4 8.0 6.2 1.8 8.8 0.3 3.5 3 1 1 4 4 4 0 Tho complex subunit 7 6PGD PF00393.19 CBK22626.2 - 8.2e-116 386.4 0.0 1e-115 386.1 0.0 1.1 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.15 CBK22626.2 - 1.9e-41 141.8 0.0 3e-41 141.2 0.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 3HCDH_N PF02737.18 CBK22626.2 - 0.13 12.2 0.0 0.22 11.4 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF1133 PF06576.11 CBK22626.2 - 0.14 11.5 0.0 0.26 10.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1133) NAD_binding_11 PF14833.6 CBK22626.2 - 0.14 12.4 0.0 0.48 10.7 0.0 1.9 2 0 0 2 2 2 0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase Rad51 PF08423.11 CBK22627.2 - 2.6e-22 79.3 0.0 3.3e-22 79.0 0.0 1.0 1 0 0 1 1 1 1 Rad51 RecA PF00154.21 CBK22627.2 - 2.2e-06 27.4 0.0 2.7e-06 27.1 0.0 1.2 1 0 0 1 1 1 1 recA bacterial DNA recombination protein DnaB_C PF03796.15 CBK22627.2 - 3.6e-06 26.5 0.0 4.4e-06 26.2 0.0 1.1 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain AAA_25 PF13481.6 CBK22627.2 - 0.00017 21.2 0.0 0.00027 20.6 0.0 1.2 1 0 0 1 1 1 1 AAA domain ATPase PF06745.13 CBK22627.2 - 0.00028 20.3 1.1 0.0015 18.0 1.1 2.0 1 1 0 1 1 1 1 KaiC MIase PF02426.16 CBK22627.2 - 0.037 14.2 0.0 0.063 13.4 0.0 1.3 1 0 0 1 1 1 0 Muconolactone delta-isomerase PAXNEB PF05625.11 CBK22627.2 - 0.32 10.1 1.3 0.65 9.1 0.2 1.8 2 0 0 2 2 2 0 PAXNEB protein SPRY PF00622.28 CBK22628.2 - 2.9e-24 85.5 0.0 4.8e-24 84.8 0.0 1.4 1 0 0 1 1 1 1 SPRY domain Sde2_N_Ubi PF13019.6 CBK22628.2 - 0.0064 16.3 0.1 0.016 15.1 0.1 1.6 1 0 0 1 1 1 1 Silencing defective 2 N-terminal ubiquitin domain zf-CCCH PF00642.24 CBK22628.2 - 0.02 14.8 2.2 0.02 14.8 2.2 2.3 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 CBK22628.2 - 0.037 13.9 0.5 0.13 12.1 0.2 2.0 2 0 0 2 2 2 0 CCCH-type zinc finger zf_CCCH_4 PF18345.1 CBK22628.2 - 0.047 13.8 2.4 0.18 11.9 0.8 2.4 2 0 0 2 2 2 0 Zinc finger domain APP_E2 PF12925.7 CBK22628.2 - 0.071 12.8 0.8 0.16 11.7 0.0 1.9 2 0 0 2 2 2 0 E2 domain of amyloid precursor protein HlyIII PF03006.20 CBK22629.2 - 1.8e-54 184.8 20.2 2.1e-54 184.6 20.2 1.0 1 0 0 1 1 1 1 Haemolysin-III related DUF5122 PF17164.4 CBK22629.2 - 0.076 13.3 0.3 0.49 10.7 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF5122) beta-propeller DUF962 PF06127.11 CBK22629.2 - 0.89 9.7 7.4 0.7 10.0 0.9 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF962) DUF454 PF04304.13 CBK22629.2 - 3.2 7.8 9.9 1 9.4 4.9 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF454) HlyIII PF03006.20 CBK22630.2 - 3.4e-46 157.8 8.5 1.4e-45 155.8 8.5 1.9 1 1 0 1 1 1 1 Haemolysin-III related Thioredoxin PF00085.20 CBK22632.2 - 1.3e-13 50.8 0.0 2.1e-13 50.1 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_6 PF13848.6 CBK22632.2 - 6.3e-05 23.0 0.0 0.00011 22.2 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_2 PF13098.6 CBK22632.2 - 0.038 14.4 0.0 0.098 13.1 0.0 1.7 2 0 0 2 2 2 0 Thioredoxin-like domain CTP_transf_1 PF01148.20 CBK22632.2 - 0.29 10.9 3.4 0.13 12.0 0.4 1.9 2 1 0 2 2 2 0 Cytidylyltransferase family Inositol_P PF00459.25 CBK22634.2 - 3e-54 184.4 0.1 3.6e-54 184.1 0.1 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family FBPase PF00316.20 CBK22634.2 - 0.0048 16.4 0.0 0.0079 15.7 0.0 1.3 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase, N-terminal domain zf-H2C2_2 PF13465.6 CBK22635.2 - 6.4e-17 61.1 27.1 1.5e-06 28.3 0.2 4.9 5 0 0 5 5 5 3 Zinc-finger double domain zf-H2C2_5 PF13909.6 CBK22635.2 - 2.2e-16 59.3 19.2 7.8e-05 22.3 0.1 4.5 4 0 0 4 4 4 4 C2H2-type zinc-finger domain zf-C2H2 PF00096.26 CBK22635.2 - 1.3e-11 44.2 25.9 0.0046 17.3 2.0 4.5 4 0 0 4 4 4 4 Zinc finger, C2H2 type CH PF00307.31 CBK22635.2 - 5.8e-06 26.5 0.0 1.4e-05 25.3 0.0 1.6 1 0 0 1 1 1 1 Calponin homology (CH) domain DUF1180 PF06679.12 CBK22635.2 - 0.0029 18.0 1.6 0.0029 18.0 1.6 2.8 3 0 0 3 3 3 1 Protein of unknown function (DUF1180) EVI2A PF05399.11 CBK22635.2 - 0.86 9.2 9.1 0.039 13.5 1.0 2.3 2 0 0 2 2 2 0 Ectropic viral integration site 2A protein (EVI2A) zf-C2H2_aberr PF17017.5 CBK22635.2 - 2 8.5 10.5 1.6 8.9 2.4 3.0 3 0 0 3 3 3 0 Aberrant zinc-finger UBA PF00627.31 CBK22637.2 - 0.00016 21.5 0.1 0.00036 20.4 0.1 1.6 1 0 0 1 1 1 1 UBA/TS-N domain ING PF12998.7 CBK22637.2 - 0.0019 18.7 0.1 0.004 17.7 0.1 1.6 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding Terminase_1 PF03354.15 CBK22637.2 - 0.15 10.6 0.0 0.18 10.3 0.0 1.1 1 0 0 1 1 1 0 Phage Terminase NUDIX PF00293.28 CBK22638.2 - 1.3e-11 44.7 0.0 1.5e-11 44.4 0.0 1.1 1 0 0 1 1 1 1 NUDIX domain NUDIX_2 PF13869.6 CBK22638.2 - 0.0007 19.2 0.0 0.00082 19.0 0.0 1.1 1 0 0 1 1 1 1 Nucleotide hydrolase NTP_transf_2 PF01909.23 CBK22639.2 - 6.6e-09 35.9 0.0 1.1e-08 35.2 0.0 1.6 1 1 0 1 1 1 1 Nucleotidyltransferase domain Polbeta PF18765.1 CBK22639.2 - 0.00011 22.2 0.0 0.00022 21.2 0.0 1.6 1 0 0 1 1 1 1 Polymerase beta, Nucleotidyltransferase MHC_I_3 PF16497.5 CBK22641.2 - 0.061 12.8 0.0 0.096 12.2 0.0 1.2 1 0 0 1 1 1 0 MHC-I family domain Tmemb_161AB PF10268.9 CBK22642.2 - 1e-08 34.3 4.3 1.2e-08 34.1 4.3 1.0 1 0 0 1 1 1 1 Predicted transmembrane protein 161AB DUF2207 PF09972.9 CBK22642.2 - 0.028 13.2 0.1 0.028 13.2 0.1 1.9 1 1 1 2 2 2 0 Predicted membrane protein (DUF2207) O-antigen_lig PF13425.6 CBK22642.2 - 0.35 9.6 8.7 0.63 8.8 8.7 1.4 1 0 0 1 1 1 0 O-antigen ligase like membrane protein Ac110_PIF PF07280.11 CBK22642.2 - 0.6 9.9 9.1 0.073 12.9 3.2 2.6 1 1 1 2 2 2 0 Per os infectivity factor AC110 ABC2_membrane_5 PF13346.6 CBK22642.2 - 1.1 8.7 15.3 0.26 10.8 9.5 2.1 2 0 0 2 2 2 0 ABC-2 family transporter protein 7TMR-DISM_7TM PF07695.11 CBK22642.2 - 2.5 8.0 26.0 0.28 11.1 8.3 2.2 1 1 1 2 2 2 0 7TM diverse intracellular signalling Pkinase PF00069.25 CBK22644.2 - 6.4e-51 173.2 0.0 1.1e-50 172.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBK22644.2 - 1e-30 106.9 1.4 4.7e-25 88.3 0.4 2.7 1 1 1 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 CBK22644.2 - 8.2e-07 28.6 0.2 1.6e-05 24.3 0.1 2.4 2 1 0 2 2 2 1 Kinase-like FTA2 PF13095.6 CBK22644.2 - 0.00016 21.4 0.1 0.038 13.6 0.1 2.3 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Pkinase_fungal PF17667.1 CBK22644.2 - 0.0028 16.5 0.0 0.0038 16.0 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 CBK22644.2 - 0.0051 16.8 0.6 1 9.3 0.9 2.2 2 0 0 2 2 2 2 Phosphotransferase enzyme family FHA PF00498.26 CBK22645.2 - 2.1e-17 63.2 0.0 3.4e-17 62.6 0.0 1.3 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 CBK22645.2 - 9.2e-08 32.3 0.0 1.4e-07 31.7 0.0 1.3 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain C2 PF00168.30 CBK22647.2 - 3.9e-06 27.1 0.0 0.04 14.2 0.0 2.5 2 0 0 2 2 2 2 C2 domain adh_short PF00106.25 CBK22649.2 - 5.8e-40 136.9 0.0 7.6e-40 136.4 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CBK22649.2 - 1.1e-23 84.0 0.0 1.5e-23 83.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CBK22649.2 - 7e-05 22.8 0.0 0.00014 21.8 0.0 1.5 1 1 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 CBK22649.2 - 0.016 15.1 0.0 0.032 14.1 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_10 PF13460.6 CBK22649.2 - 0.051 13.5 0.0 0.091 12.6 0.0 1.4 1 0 0 1 1 1 0 NAD(P)H-binding DDE_Tnp_ISL3 PF01610.17 CBK22649.2 - 0.086 12.5 0.0 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 Transposase Polysacc_synt_2 PF02719.15 CBK22649.2 - 0.12 11.5 0.1 0.2 10.8 0.1 1.4 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein ProRS-C_1 PF09180.11 CBK22649.2 - 0.14 12.3 0.1 0.35 11.1 0.1 1.6 1 0 0 1 1 1 0 Prolyl-tRNA synthetase, C-terminal Ribosomal_L6 PF00347.23 CBK22650.2 - 3.7e-27 94.8 3.6 3.5e-14 53.2 0.2 2.1 2 0 0 2 2 2 2 Ribosomal protein L6 Rota_VP4_MID PF17477.2 CBK22650.2 - 0.022 14.2 0.0 0.028 13.8 0.0 1.2 1 0 0 1 1 1 0 Rotavirus VP4 membrane interaction domain S4 PF01479.25 CBK22651.2 - 1.8e-12 46.8 0.4 1.8e-12 46.8 0.4 2.2 2 0 0 2 2 2 1 S4 domain zf-DBF PF07535.12 CBK22651.2 - 0.11 12.6 0.0 0.26 11.4 0.0 1.6 1 0 0 1 1 1 0 DBF zinc finger PI3_PI4_kinase PF00454.27 CBK22652.2 - 7.2e-39 134.1 0.9 1.1e-38 133.5 0.9 1.3 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.20 CBK22652.2 - 1.9e-14 53.2 0.0 4.7e-14 51.9 0.0 1.8 1 0 0 1 1 1 1 FATC domain EamA PF00892.20 CBK22653.2 - 2.6e-16 60.0 32.7 3.4e-10 40.2 11.1 2.1 2 0 0 2 2 2 2 EamA-like transporter family DMT_YdcZ PF04657.13 CBK22653.2 - 0.17 12.2 21.4 0.23 11.7 4.8 3.0 2 1 1 3 3 3 0 Putative inner membrane exporter, YdcZ LRR_6 PF13516.6 CBK22654.2 - 1.6e-10 40.1 18.5 0.0041 17.0 0.1 8.1 10 0 0 10 10 10 4 Leucine Rich repeat LRR_4 PF12799.7 CBK22654.2 - 0.00075 19.8 25.6 0.056 13.9 0.0 6.9 7 2 2 9 9 9 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CBK22654.2 - 0.0025 17.5 14.3 1.2 9.0 0.9 7.0 8 3 0 8 8 8 2 Leucine rich repeat LRR_1 PF00560.33 CBK22654.2 - 0.18 12.4 18.4 2.7 8.9 0.8 7.1 9 0 0 9 9 9 0 Leucine Rich Repeat Peptidase_M17 PF00883.21 CBK22656.2 - 5.1e-106 354.5 0.0 6e-106 354.2 0.0 1.0 1 0 0 1 1 1 1 Cytosol aminopeptidase family, catalytic domain RNA_pol_Rpb2_6 PF00562.28 CBK22657.2 - 1.3e-123 412.9 0.0 1.9e-123 412.4 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 CBK22657.2 - 1.2e-36 126.1 0.1 1.7e-36 125.6 0.1 1.2 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.14 CBK22657.2 - 3.3e-35 121.5 0.0 8.2e-35 120.2 0.0 1.7 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.20 CBK22657.2 - 1.6e-31 108.5 0.1 5.8e-31 106.8 0.1 2.1 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_3 PF04565.16 CBK22657.2 - 4.7e-23 81.1 0.1 1.2e-22 79.9 0.1 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.17 CBK22657.2 - 3e-14 53.3 0.7 1.4e-13 51.1 0.7 2.3 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 RNA_pol_Rpb2_4 PF04566.13 CBK22657.2 - 4.6e-13 49.2 0.1 4.6e-13 49.2 0.1 3.4 5 0 0 5 5 5 1 RNA polymerase Rpb2, domain 4 zf-CCCH PF00642.24 CBK22658.2 - 2.4e-08 33.7 0.9 7e-08 32.2 0.9 1.8 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-C3HC4_3 PF13920.6 CBK22658.2 - 4.7e-08 32.8 8.8 8.8e-08 31.9 8.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CBK22658.2 - 1.3e-07 31.4 10.4 3.1e-07 30.3 10.4 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 CBK22658.2 - 1.8e-07 31.1 10.1 1.8e-07 31.1 10.1 2.0 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 CBK22658.2 - 2.7e-07 30.3 8.8 6.1e-07 29.2 8.8 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf_CCCH_4 PF18345.1 CBK22658.2 - 4.1e-07 29.8 1.8 8.9e-07 28.8 1.8 1.6 1 0 0 1 1 1 1 Zinc finger domain zf-C3HC4 PF00097.25 CBK22658.2 - 2.2e-06 27.4 10.1 5.4e-06 26.2 10.1 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CBK22658.2 - 7.9e-06 26.1 8.0 7.9e-06 26.1 8.0 1.9 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_4 PF15227.6 CBK22658.2 - 5.4e-05 23.3 9.0 5.4e-05 23.3 9.0 2.0 2 0 0 2 2 1 1 zinc finger of C3HC4-type, RING zf-CCCH_4 PF18044.1 CBK22658.2 - 0.00015 21.5 1.0 0.00015 21.5 1.0 2.2 2 0 0 2 2 2 1 CCCH-type zinc finger Prok-RING_4 PF14447.6 CBK22658.2 - 0.0008 19.2 8.6 0.0016 18.3 8.6 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_10 PF16685.5 CBK22658.2 - 0.0017 18.4 5.4 0.0017 18.4 5.4 1.8 2 0 0 2 2 2 1 zinc RING finger of MSL2 zf-Nse PF11789.8 CBK22658.2 - 0.02 14.7 4.7 0.033 14.0 4.7 1.3 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit FYVE_2 PF02318.16 CBK22658.2 - 0.66 10.2 8.5 0.76 10.0 7.1 1.8 1 1 0 1 1 1 0 FYVE-type zinc finger C1_2 PF03107.16 CBK22658.2 - 7.5 7.0 11.9 8.1 6.9 3.7 2.6 1 1 1 2 2 2 0 C1 domain CDP-OH_P_transf PF01066.21 CBK22659.2 - 1.9e-13 50.9 1.8 1.9e-13 50.9 1.8 2.4 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase GILT PF03227.16 CBK22660.2 - 5.1e-81 267.8 11.2 2.5e-26 92.0 0.5 3.3 3 0 0 3 3 3 3 Gamma interferon inducible lysosomal thiol reductase (GILT) GST_N_3 PF13417.6 CBK22660.2 - 0.00025 21.4 0.0 6 7.3 0.0 3.5 3 0 0 3 3 3 2 Glutathione S-transferase, N-terminal domain Thioredoxin_4 PF13462.6 CBK22660.2 - 0.00038 20.7 5.3 8.4 6.5 0.1 4.9 3 3 0 3 3 3 3 Thioredoxin BOP1NT PF08145.12 CBK22660.2 - 0.00085 19.3 0.0 1.4 8.8 0.0 2.9 3 0 0 3 3 3 2 BOP1NT (NUC169) domain Galactosyl_T PF01762.21 CBK22660.2 - 0.0041 17.0 0.2 6.1 6.6 0.0 3.1 3 0 0 3 3 3 1 Galactosyltransferase Coatamer_beta_C PF07718.12 CBK22660.2 - 0.005 16.8 0.0 17 5.3 0.0 3.1 3 0 0 3 3 3 1 Coatomer beta C-terminal region zf-CCCH_8 PF18633.1 CBK22660.2 - 0.011 15.9 12.1 2.5 8.3 1.3 3.9 3 0 0 3 3 3 0 Zinc-finger antiviral protein (ZAP) zinc finger domain 3 DUF1438 PF07270.11 CBK22660.2 - 0.19 11.8 8.4 20 5.3 0.2 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1438) zf-U1 PF06220.12 CBK22660.2 - 1.8 8.4 5.1 72 3.3 0.2 3.3 3 0 0 3 3 3 0 U1 zinc finger DUF2752 PF10825.8 CBK22660.2 - 3.4 7.8 5.7 81 3.4 0.0 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2752) Peptidase_C13 PF01650.18 CBK22661.2 - 4.6e-50 170.5 0.0 9.2e-50 169.5 0.0 1.4 2 0 0 2 2 2 1 Peptidase C13 family PEPCK_ATP PF01293.20 CBK22662.2 - 1.6e-212 706.2 0.0 1.9e-212 706.0 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase SNF2_N PF00176.23 CBK22663.2 - 4.4e-57 193.4 0.1 6.6e-57 192.8 0.1 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 CBK22663.2 - 3.4e-21 75.7 0.0 7.3e-20 71.4 0.0 3.2 5 0 0 5 5 5 1 Helicase conserved C-terminal domain ResIII PF04851.15 CBK22663.2 - 5.1e-07 29.9 0.0 1.3e-05 25.2 0.0 2.6 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.29 CBK22663.2 - 0.0029 17.4 0.0 0.0069 16.2 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Serglycin PF04360.12 CBK22663.2 - 3 7.8 7.1 9.4 6.2 7.1 1.7 1 1 0 1 1 1 0 Serglycin DUF4407 PF14362.6 CBK22663.2 - 10 5.4 10.5 44 3.3 10.4 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) EMP24_GP25L PF01105.24 CBK22664.2 - 3.4e-28 98.8 2.9 3.8e-28 98.6 2.9 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD AhpC-TSA PF00578.21 CBK22665.2 - 8.1e-36 122.7 0.0 1.1e-35 122.3 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family 1-cysPrx_C PF10417.9 CBK22665.2 - 2.3e-12 46.5 0.0 4.8e-12 45.5 0.0 1.5 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin Redoxin PF08534.10 CBK22665.2 - 1.2e-11 44.6 0.0 1.5e-11 44.2 0.0 1.1 1 0 0 1 1 1 1 Redoxin HA2 PF04408.23 CBK22666.2 - 1.5e-23 83.1 0.0 3.1e-23 82.1 0.0 1.5 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 CBK22666.2 - 2e-20 72.9 0.0 4.2e-20 71.9 0.0 1.5 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 CBK22666.2 - 1.9e-14 53.9 0.0 4.5e-14 52.7 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 CBK22666.2 - 1e-07 31.9 0.1 2.1e-07 30.9 0.1 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_19 PF13245.6 CBK22666.2 - 3.8e-06 27.3 0.1 8.2e-06 26.2 0.1 1.5 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 CBK22666.2 - 7.4e-05 21.9 0.0 0.00015 20.9 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_22 PF13401.6 CBK22666.2 - 0.00056 20.2 0.0 0.0014 18.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain SRP54 PF00448.22 CBK22666.2 - 0.0017 18.0 0.0 0.0039 16.8 0.0 1.6 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain AAA_30 PF13604.6 CBK22666.2 - 0.0039 16.9 0.0 0.0065 16.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain ResIII PF04851.15 CBK22666.2 - 0.0045 17.0 0.0 0.027 14.5 0.0 2.1 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DUF2075 PF09848.9 CBK22666.2 - 0.03 13.6 0.0 0.044 13.0 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) ABC_tran PF00005.27 CBK22666.2 - 0.13 12.7 0.2 4.1 7.9 0.2 2.4 1 1 0 1 1 1 0 ABC transporter Sigma54_activat PF00158.26 CBK22666.2 - 0.18 11.5 0.0 0.36 10.5 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain CTP_synth_N PF06418.14 CBK22667.2 - 6.5e-125 415.8 0.1 8.7e-125 415.4 0.1 1.2 1 0 0 1 1 1 1 CTP synthase N-terminus GATase PF00117.28 CBK22667.2 - 4.4e-51 173.3 0.0 7e-51 172.7 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 CBK22667.2 - 1.6e-06 28.0 0.2 4e-06 26.7 0.0 1.7 2 0 0 2 2 2 1 Peptidase C26 CbiA PF01656.23 CBK22667.2 - 0.016 15.2 0.0 0.023 14.8 0.0 1.5 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain DUF2726 PF10881.8 CBK22667.2 - 0.16 11.9 0.0 0.37 10.7 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2726) Spectrin PF00435.21 CBK22668.2 - 0.017 15.6 0.4 0.037 14.5 0.4 1.4 1 0 0 1 1 1 0 Spectrin repeat CHASE3 PF05227.13 CBK22668.2 - 0.021 14.7 0.1 0.032 14.1 0.1 1.2 1 0 0 1 1 1 0 CHASE3 domain SIKE PF05769.11 CBK22668.2 - 0.023 14.6 1.1 0.036 14.0 1.1 1.2 1 0 0 1 1 1 0 SIKE family zf-CCHC_3 PF13917.6 CBK22669.2 - 1.8e-15 56.6 5.7 3.5e-15 55.7 5.7 1.5 1 0 0 1 1 1 1 Zinc knuckle Zn_ribbon_2 PF12674.7 CBK22669.2 - 0.02 15.5 1.0 0.19 12.4 0.2 2.2 2 0 0 2 2 2 0 Putative zinc ribbon domain TniQ PF06527.11 CBK22669.2 - 0.61 10.8 5.5 0.27 12.0 2.6 1.8 2 0 0 2 2 2 0 TniQ IMUP PF15761.5 CBK22669.2 - 1.5 9.5 5.8 0.58 10.9 1.2 2.3 2 0 0 2 2 2 0 Immortalisation up-regulated protein Phospholip_B PF04916.13 CBK22670.2 - 7.3e-144 480.2 4.2 8.9e-144 480.0 4.2 1.0 1 0 0 1 1 1 1 Phospholipase B Helicase_C PF00271.31 CBK22671.2 - 8.3e-18 64.8 0.0 1.3e-15 57.7 0.0 2.9 2 1 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 CBK22671.2 - 3.5e-11 43.2 0.0 5.8e-11 42.5 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase GHMP_kinases_C PF08544.13 CBK22671.2 - 0.1 13.0 0.0 0.27 11.6 0.0 1.7 1 0 0 1 1 1 0 GHMP kinases C terminal Smr PF01713.21 CBK22672.2 - 9.6e-05 22.7 0.0 0.00019 21.7 0.0 1.5 1 0 0 1 1 1 1 Smr domain BDHCT_assoc PF16204.5 CBK22672.2 - 0.0003 20.5 0.8 0.00064 19.5 0.8 1.7 1 1 0 1 1 1 1 BDHCT-box associated domain on Bloom syndrome protein Pribosyltran_N PF13793.6 CBK22673.2 - 8.4e-42 141.8 0.0 3.3e-40 136.6 0.0 2.3 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.6 CBK22673.2 - 1.1e-21 77.7 0.5 2.3e-21 76.7 0.5 1.6 1 0 0 1 1 1 1 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.27 CBK22673.2 - 2e-07 30.7 0.3 3.8e-06 26.5 0.2 2.3 2 0 0 2 2 2 1 Phosphoribosyl transferase domain UPRTase PF14681.6 CBK22673.2 - 0.032 13.7 0.1 0.063 12.7 0.1 1.4 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase GYF PF02213.16 CBK22674.2 - 6.8e-09 35.3 0.2 1.2e-08 34.5 0.2 1.4 1 0 0 1 1 1 1 GYF domain FSH1 PF03959.13 CBK22675.2 - 0.0013 18.4 0.0 0.0016 18.1 0.0 1.2 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Peptidase_S9 PF00326.21 CBK22675.2 - 0.027 14.0 0.0 0.035 13.6 0.0 1.1 1 0 0 1 1 1 0 Prolyl oligopeptidase family Abhydrolase_2 PF02230.16 CBK22675.2 - 0.036 13.9 0.0 0.051 13.4 0.0 1.2 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase DLH PF01738.18 CBK22675.2 - 0.048 13.2 0.0 0.066 12.8 0.0 1.2 1 0 0 1 1 1 0 Dienelactone hydrolase family Abhydrolase_1 PF00561.20 CBK22675.2 - 0.14 11.7 0.0 0.15 11.7 0.0 1.1 1 0 0 1 1 1 0 alpha/beta hydrolase fold Pentapeptide_4 PF13599.6 CBK22677.2 - 0.05 13.8 0.0 0.062 13.5 0.0 1.3 1 0 0 1 1 1 0 Pentapeptide repeats (9 copies) YabA PF06156.13 CBK22678.2 - 0.00076 20.1 4.6 0.00076 20.1 4.6 9.2 4 2 5 9 9 9 2 Initiation control protein YabA Tropomyosin_1 PF12718.7 CBK22678.2 - 0.00097 19.3 16.4 0.00097 19.3 16.4 8.6 5 3 2 8 8 8 1 Tropomyosin like Fez1 PF06818.15 CBK22678.2 - 0.0015 19.0 18.5 0.0015 19.0 18.5 6.4 3 3 2 6 6 6 1 Fez1 Fib_alpha PF08702.10 CBK22678.2 - 0.0025 18.0 8.1 0.0025 18.0 8.1 7.3 6 1 2 8 8 8 4 Fibrinogen alpha/beta chain family DUF3800 PF12686.7 CBK22678.2 - 0.067 13.8 2.0 32 5.2 2.0 4.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3800) TPR_MLP1_2 PF07926.12 CBK22679.2 - 0.0025 17.9 32.3 0.0025 17.9 32.3 11.1 1 1 9 10 10 10 4 TPR/MLP1/MLP2-like protein Fib_alpha PF08702.10 CBK22679.2 - 0.0044 17.2 12.3 0.0044 17.2 12.3 8.2 2 2 6 8 8 8 3 Fibrinogen alpha/beta chain family E1_DerP2_DerF2 PF02221.15 CBK22680.2 - 0.00034 21.0 0.0 0.00045 20.7 0.0 1.2 1 0 0 1 1 1 1 ML domain Pkinase PF00069.25 CBK22681.2 - 0.0052 16.2 0.0 0.0071 15.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain tRNA_synthFbeta PF17759.1 CBK22684.2 - 9.8e-46 155.9 0.0 4.4e-45 153.8 0.0 1.9 2 0 0 2 2 2 1 Phenylalanyl tRNA synthetase beta chain CLM domain B3_4 PF03483.17 CBK22684.2 - 8.6e-20 71.1 0.0 1.7e-19 70.1 0.0 1.5 1 0 0 1 1 1 1 B3/4 domain B5 PF03484.15 CBK22684.2 - 4.1e-14 52.6 0.0 9.9e-13 48.2 0.0 2.5 2 0 0 2 2 2 1 tRNA synthetase B5 domain PhetRS_B1 PF18262.1 CBK22684.2 - 1.3e-12 47.8 0.0 6e-12 45.6 0.0 2.1 2 0 0 2 2 2 1 Phe-tRNA synthetase beta subunit B1 domain tRNA-synt_2d PF01409.20 CBK22684.2 - 0.18 11.2 0.1 16 4.9 0.0 2.7 3 0 0 3 3 3 0 tRNA synthetases class II core domain (F) LRR_6 PF13516.6 CBK22685.2 - 3.9e-09 35.8 1.3 0.001 19.0 0.0 4.7 5 0 0 5 5 5 2 Leucine Rich repeat LRR_4 PF12799.7 CBK22685.2 - 0.077 13.5 12.0 0.1 13.0 3.4 4.3 1 1 2 3 3 3 0 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CBK22685.2 - 0.34 10.7 7.0 4.1 7.2 0.2 4.0 3 0 0 3 3 3 0 Leucine rich repeat LRR_1 PF00560.33 CBK22685.2 - 0.9 10.3 13.0 1.5 9.7 1.8 4.4 3 1 0 3 3 3 0 Leucine Rich Repeat HAD_2 PF13419.6 CBK22688.2 - 6.9e-23 81.6 0.0 8.5e-23 81.4 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 CBK22688.2 - 1.5e-10 41.7 0.0 9.3e-10 39.1 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 CBK22688.2 - 0.00014 21.8 0.0 0.00034 20.6 0.0 1.7 1 0 0 1 1 1 1 HAD-hyrolase-like HAD PF12710.7 CBK22688.2 - 0.0079 16.6 0.0 0.013 16.0 0.0 1.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Y_phosphatase3 PF13350.6 CBK22689.2 - 0.0054 16.7 0.0 0.0062 16.5 0.0 1.2 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 CBK22689.2 - 0.029 13.9 0.0 0.049 13.2 0.0 1.3 1 0 0 1 1 1 0 Protein-tyrosine phosphatase DSPc PF00782.20 CBK22689.2 - 0.11 12.3 0.1 0.32 10.8 0.0 1.8 2 0 0 2 2 2 0 Dual specificity phosphatase, catalytic domain IpgD PF05925.12 CBK22689.2 - 0.13 10.8 0.0 0.18 10.3 0.0 1.2 1 0 0 1 1 1 0 Enterobacterial virulence protein IpgD Proteasome PF00227.26 CBK22690.2 - 7.6e-47 159.3 0.1 9.3e-47 159.0 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Skp1_POZ PF03931.15 CBK22691.2 - 1.4e-11 44.4 1.0 1.4e-11 44.4 1.0 1.5 2 0 0 2 2 2 1 Skp1 family, tetramerisation domain RIX1 PF08167.12 CBK22691.2 - 0.15 11.8 0.0 0.18 11.6 0.0 1.3 1 0 0 1 1 1 0 rRNA processing/ribosome biogenesis Glyco_transf_49 PF13896.6 CBK22692.2 - 4.3e-07 29.6 1.2 6.1e-07 29.1 1.2 1.2 1 0 0 1 1 1 1 Glycosyl-transferase for dystroglycan Glyco_hydro_35 PF01301.19 CBK22693.2 - 3e-106 355.6 1.0 4.5e-106 355.1 1.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 Glyco_hydro_42 PF02449.15 CBK22693.2 - 5.2e-18 65.5 0.1 4.6e-16 59.1 0.1 2.2 1 1 0 1 1 1 1 Beta-galactosidase BetaGal_dom4_5 PF13364.6 CBK22693.2 - 0.0012 19.4 0.1 0.003 18.1 0.1 1.6 1 0 0 1 1 1 1 Beta-galactosidase jelly roll domain Cellulase PF00150.18 CBK22693.2 - 0.0012 18.3 0.0 0.002 17.6 0.0 1.3 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) HSP70 PF00012.20 CBK22694.2 - 6.6e-46 156.7 2.4 7.8e-46 156.5 2.4 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 CBK22694.2 - 1e-10 41.0 0.1 1.1e-08 34.3 0.0 2.3 2 1 0 2 2 2 2 MreB/Mbl protein YqzH PF14164.6 CBK22694.2 - 0.018 15.1 0.5 0.044 13.8 0.5 1.6 1 0 0 1 1 1 0 YqzH-like protein Hydantoinase_A PF01968.18 CBK22694.2 - 0.051 12.8 0.2 1.2 8.3 0.0 2.4 2 1 0 2 2 2 0 Hydantoinase/oxoprolinase FtsA PF14450.6 CBK22694.2 - 0.078 13.4 0.7 0.53 10.7 0.4 2.4 2 1 0 2 2 2 0 Cell division protein FtsA BRCT_2 PF16589.5 CBK22695.2 - 4e-08 33.5 0.0 9.3e-08 32.4 0.0 1.6 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 CBK22695.2 - 2.2e-05 24.8 0.0 5.5e-05 23.5 0.0 1.7 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain LIG3_BRCT PF16759.5 CBK22695.2 - 0.051 13.9 2.3 0.057 13.7 0.0 2.3 3 1 0 3 3 3 0 DNA ligase 3 BRCT domain Pescadillo_N PF06732.11 CBK22696.2 - 4.7e-108 360.9 0.6 7.1e-108 360.3 0.6 1.2 1 0 0 1 1 1 1 Pescadillo N-terminus AMP-binding PF00501.28 CBK22696.2 - 2e-76 257.3 0.0 2.7e-76 256.9 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 CBK22696.2 - 0.01 16.8 0.0 0.021 15.8 0.0 1.5 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain FAM60A PF15396.6 CBK22697.2 - 4.6 7.2 11.9 5.4 7.0 11.9 1.1 1 0 0 1 1 1 0 Protein Family FAM60A Presenilin PF01080.17 CBK22697.2 - 5.7 5.6 10.5 6.5 5.4 10.5 1.0 1 0 0 1 1 1 0 Presenilin ATP11 PF06644.11 CBK22697.2 - 7.7 6.2 12.3 9.3 5.9 12.3 1.1 1 0 0 1 1 1 0 ATP11 protein RR_TM4-6 PF06459.12 CBK22697.2 - 8.8 6.1 19.5 12 5.6 19.5 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 EF-hand_1 PF00036.32 CBK22698.2 - 1.7e-11 42.8 0.0 0.00033 20.0 0.0 2.7 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 CBK22698.2 - 1.7e-10 41.2 0.3 5.7e-10 39.5 0.0 2.1 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 CBK22698.2 - 1.2e-09 37.3 0.0 0.0007 19.3 0.0 2.8 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 CBK22698.2 - 4.6e-09 36.2 0.0 1.2e-08 34.8 0.0 1.7 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand EF-hand_5 PF13202.6 CBK22698.2 - 2e-08 33.4 0.1 0.0013 18.2 0.0 3.0 2 0 0 2 2 2 2 EF hand DUF812 PF05667.11 CBK22698.2 - 3.4e-06 26.2 1.1 4e-06 26.0 1.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF812) EF-hand_8 PF13833.6 CBK22698.2 - 1.5e-05 24.8 0.6 0.0049 16.7 0.1 2.7 1 1 1 2 2 2 2 EF-hand domain pair SPARC_Ca_bdg PF10591.9 CBK22698.2 - 0.0012 19.1 3.1 0.0026 18.0 0.1 2.6 2 0 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region Cauli_AT PF03233.13 CBK22698.2 - 0.059 13.3 3.3 0.1 12.5 3.3 1.4 1 0 0 1 1 1 0 Aphid transmission protein Mgr1 PF08602.10 CBK22698.2 - 0.094 11.5 0.6 0.17 10.7 0.6 1.3 1 0 0 1 1 1 0 Mgr1-like, i-AAA protease complex subunit DivIC PF04977.15 CBK22698.2 - 0.48 10.2 11.5 0.083 12.7 7.3 1.9 2 0 0 2 2 2 0 Septum formation initiator DUF4407 PF14362.6 CBK22698.2 - 1.4 8.2 4.3 16 4.7 3.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) MFS_1 PF07690.16 CBK22699.2 - 3.3e-13 49.3 1.8 1.7e-12 47.0 1.6 1.9 1 1 0 1 1 1 1 Major Facilitator Superfamily OATP PF03137.20 CBK22699.2 - 7.8e-05 21.2 0.1 0.00012 20.5 0.1 1.3 1 0 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family MFS_1_like PF12832.7 CBK22699.2 - 0.00031 19.7 1.5 0.13 11.1 0.1 2.3 2 0 0 2 2 2 2 MFS_1 like family DUF5316 PF17247.2 CBK22699.2 - 0.0071 16.3 0.5 0.34 11.0 0.0 3.1 3 0 0 3 3 3 1 Family of unknown function (DUF5316) Transcrip_act PF04949.13 CBK22701.2 - 1.6e-08 34.6 19.5 3.2e-08 33.6 18.3 1.9 1 1 0 1 1 1 1 Transcriptional activator Phasin PF05597.11 CBK22701.2 - 0.00065 19.7 5.4 0.00065 19.7 5.4 2.5 1 1 2 3 3 3 1 Poly(hydroxyalcanoate) granule associated protein (phasin) BORCS8 PF10167.9 CBK22701.2 - 0.025 14.5 3.7 0.045 13.7 2.8 1.9 1 1 0 1 1 1 0 BLOC-1-related complex sub-unit 8 Pox_A_type_inc PF04508.12 CBK22701.2 - 0.038 13.8 4.9 0.066 13.1 0.5 3.0 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat MIT_C PF16565.5 CBK22701.2 - 0.37 10.8 5.5 0.2 11.6 3.0 1.8 1 1 0 2 2 2 0 Phospholipase D-like domain at C-terminus of MIT DUF489 PF04356.12 CBK22701.2 - 0.4 10.7 5.4 11 6.0 2.5 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF489) MPS2 PF17060.5 CBK22701.2 - 0.41 9.9 19.6 0.23 10.7 2.8 2.1 1 1 1 2 2 2 0 Monopolar spindle protein 2 Laminin_II PF06009.12 CBK22701.2 - 0.86 9.6 15.3 0.043 13.8 6.3 2.6 1 1 1 2 2 2 0 Laminin Domain II DUF4407 PF14362.6 CBK22701.2 - 1.2 8.4 11.1 1.8 7.9 11.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF1664 PF07889.12 CBK22701.2 - 1.4 8.9 12.3 0.11 12.5 4.3 2.5 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) CENP-F_leu_zip PF10473.9 CBK22701.2 - 2.3 8.3 29.5 0.076 13.0 8.7 2.8 1 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ING PF12998.7 CBK22701.2 - 5 7.8 18.0 0.67 10.6 8.3 3.0 1 1 2 3 3 3 0 Inhibitor of growth proteins N-terminal histone-binding COG2 PF06148.11 CBK22701.2 - 6.2 6.9 12.6 1.4 9.0 1.8 3.1 1 1 1 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 TolA_bind_tri PF16331.5 CBK22701.2 - 6.8 6.8 13.6 1.4 9.0 3.8 3.4 4 0 0 4 4 4 0 TolA binding protein trimerisation Fzo_mitofusin PF04799.13 CBK22701.2 - 7.9 6.0 11.4 3.4 7.2 6.8 2.4 1 1 1 2 2 2 0 fzo-like conserved region DUF1764 PF08576.10 CBK22702.2 - 0.43 11.5 0.1 0.43 11.5 0.1 3.0 3 1 0 3 3 3 0 Eukaryotic protein of unknown function (DUF1764) Orf78 PF06024.12 CBK22702.2 - 1.3 9.4 8.8 0.1 12.9 0.9 2.6 2 0 0 2 2 2 0 Orf78 (ac78) Zip PF02535.22 CBK22702.2 - 8.2 5.5 6.6 10 5.2 1.3 2.1 2 0 0 2 2 2 0 ZIP Zinc transporter Cas6_N PF17952.1 CBK22703.2 - 0.049 13.9 0.0 0.068 13.4 0.0 1.4 1 0 0 1 1 1 0 Cas6 N-terminal domain HSP70 PF00012.20 CBK22703.2 - 0.13 10.4 0.2 0.2 9.8 0.1 1.2 1 1 0 1 1 1 0 Hsp70 protein RRM_2 PF04059.12 CBK22705.2 - 5.1e-20 71.5 0.1 6.9e-20 71.1 0.1 1.2 1 0 0 1 1 1 1 RNA recognition motif 2 DWNN PF08783.11 CBK22706.2 - 2.9e-10 40.3 0.1 5e-10 39.5 0.1 1.4 1 0 0 1 1 1 1 DWNN domain zf-CCHC_2 PF13696.6 CBK22706.2 - 0.0016 18.3 4.2 0.0039 17.0 4.2 1.7 1 0 0 1 1 1 1 Zinc knuckle LsmAD PF06741.13 CBK22707.2 - 1.6e-10 41.3 0.0 1.6e-10 41.3 0.0 2.2 2 0 0 2 2 2 1 LsmAD domain Collagen PF01391.18 CBK22707.2 - 0.0046 16.7 4.5 0.0046 16.7 4.5 2.4 2 0 0 2 2 2 1 Collagen triple helix repeat (20 copies) RNA_polI_A34 PF08208.11 CBK22707.2 - 0.61 10.1 9.8 0.82 9.7 9.8 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 DUF4746 PF15928.5 CBK22707.2 - 8.4 5.7 9.6 11 5.4 9.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Ank_4 PF13637.6 CBK22708.2 - 7.3e-25 87.0 9.2 6.7e-13 48.9 0.1 4.3 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 CBK22708.2 - 4.4e-21 75.3 5.9 4e-15 56.2 0.3 3.0 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 CBK22708.2 - 4.5e-19 66.5 2.7 0.00028 21.1 0.0 5.2 6 0 0 6 6 6 3 Ankyrin repeat Ank PF00023.30 CBK22708.2 - 1.3e-18 66.5 4.6 0.00035 20.9 0.0 5.8 6 0 0 6 6 6 4 Ankyrin repeat Ank_5 PF13857.6 CBK22708.2 - 2e-18 66.2 4.7 1.3e-08 34.9 0.3 3.2 3 1 1 4 4 4 3 Ankyrin repeats (many copies) GLTP PF08718.11 CBK22709.2 - 5e-31 108.0 0.3 6.8e-31 107.6 0.3 1.2 1 0 0 1 1 1 1 Glycolipid transfer protein (GLTP) Orthopox_A5L PF06193.11 CBK22710.2 - 0.058 12.8 0.3 0.095 12.1 0.1 1.4 2 0 0 2 2 2 0 Orthopoxvirus A5L protein-like DNA_pol_E_B PF04042.16 CBK22712.2 - 2e-22 79.6 0.3 2.4e-22 79.3 0.3 1.0 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B DNA_pol_D_N PF18018.1 CBK22713.2 - 3.2e-16 59.6 0.0 4.2e-16 59.2 0.0 1.1 1 0 0 1 1 1 1 DNA polymerase delta subunit OB-fold domain He_PIG PF05345.12 CBK22715.2 - 1e-27 96.1 42.2 5.9e-06 26.4 1.0 7.4 7 0 0 7 7 7 6 Putative Ig domain DUF11 PF01345.18 CBK22715.2 - 0.0001 22.5 0.0 1 9.7 0.0 5.1 3 2 1 4 4 4 1 Domain of unknown function DUF11 I-set PF07679.16 CBK22715.2 - 0.0017 18.4 5.2 5.9 7.0 0.1 4.5 4 0 0 4 4 4 2 Immunoglobulin I-set domain F5_F8_type_C PF00754.25 CBK22715.2 - 0.0096 16.0 8.6 0.028 14.5 0.5 3.4 2 0 0 2 2 2 1 F5/8 type C domain Toxin_28 PF08115.11 CBK22715.2 - 0.14 12.1 0.1 0.34 10.8 0.1 1.7 1 0 0 1 1 1 0 SFI toxin family HRM PF02793.22 CBK22715.2 - 0.14 12.5 13.6 0.85 10.0 0.1 4.8 5 0 0 5 5 5 0 Hormone receptor domain DUF3185 PF11381.8 CBK22715.2 - 0.54 10.3 6.1 1.9 8.6 6.1 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3185) Thg1 PF04446.12 CBK22716.2 - 1.1e-47 161.1 0.3 1.9e-47 160.4 0.3 1.4 1 0 0 1 1 1 1 tRNAHis guanylyltransferase Thg1C PF14413.6 CBK22716.2 - 4.2e-47 159.3 0.1 6.7e-47 158.6 0.1 1.3 1 0 0 1 1 1 1 Thg1 C terminal domain WD40 PF00400.32 CBK22717.2 - 6e-25 87.0 9.3 0.00029 21.6 0.1 5.8 5 1 0 5 5 5 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBK22717.2 - 0.0019 18.5 0.2 23 5.4 0.0 4.6 3 2 2 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 CBK22717.2 - 0.0078 15.6 0.0 0.26 10.6 0.0 2.8 3 1 0 3 3 3 1 WD40-like domain BBS2_Mid PF14783.6 CBK22717.2 - 0.01 15.9 0.0 0.18 11.8 0.0 2.7 3 0 0 3 3 3 0 Ciliary BBSome complex subunit 2, middle region Diphthami_syn_2 PF01902.17 CBK22717.2 - 0.038 13.5 0.4 4.5 6.7 0.0 2.8 3 0 0 3 3 3 0 Diphthamide synthase End3 PF12761.7 CBK22717.2 - 0.046 13.9 4.6 0.072 13.3 4.6 1.3 1 0 0 1 1 1 0 Actin cytoskeleton-regulatory complex protein END3 DUF3752 PF12572.8 CBK22717.2 - 8 7.0 9.2 1.3 9.5 4.7 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF3752) Cystatin PF00031.21 CBK22718.2 - 7.9e-11 42.1 0.2 9.4e-11 41.8 0.2 1.1 1 0 0 1 1 1 1 Cystatin domain Rota_NS53 PF00981.17 CBK22718.2 - 0.045 12.6 0.2 0.048 12.5 0.2 1.0 1 0 0 1 1 1 0 Rotavirus RNA-binding Protein 53 (NS53) AARP2CN PF08142.12 CBK22719.2 - 2.8e-27 94.6 0.0 2.8e-27 94.6 0.0 3.6 2 1 0 2 2 1 1 AARP2CN (NUC121) domain GTP_EFTU PF00009.27 CBK22719.2 - 0.00036 20.1 5.7 0.0052 16.3 0.0 3.0 2 1 1 3 3 2 2 Elongation factor Tu GTP binding domain AAA_22 PF13401.6 CBK22719.2 - 0.00037 20.8 0.0 0.00084 19.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 CBK22719.2 - 0.0016 18.9 0.0 0.012 16.1 0.0 2.5 1 0 0 1 1 1 1 AAA ATPase domain PduV-EutP PF10662.9 CBK22719.2 - 0.003 17.3 0.0 0.0064 16.2 0.0 1.5 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation MMR_HSR1 PF01926.23 CBK22719.2 - 0.0058 16.7 0.1 0.022 14.9 0.1 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_14 PF13173.6 CBK22719.2 - 0.006 16.6 0.0 0.02 14.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 CBK22719.2 - 0.0079 16.6 0.4 0.019 15.4 0.0 1.8 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 CBK22719.2 - 0.031 14.7 0.0 0.11 12.9 0.0 2.0 1 0 0 1 1 1 0 RNA helicase Roc PF08477.13 CBK22719.2 - 0.12 12.6 0.1 0.24 11.6 0.1 1.5 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase NTPase_1 PF03266.15 CBK22719.2 - 0.16 11.9 1.7 0.26 11.2 0.7 1.9 2 0 0 2 2 2 0 NTPase AAA_33 PF13671.6 CBK22719.2 - 0.23 11.6 2.3 0.3 11.3 0.1 2.4 2 1 0 2 2 2 0 AAA domain ABC_tran PF00005.27 CBK22719.2 - 0.68 10.4 0.0 0.68 10.4 0.0 2.6 2 1 0 2 2 1 0 ABC transporter F_actin_cap_B PF01115.17 CBK22720.2 - 4.1e-77 259.0 0.4 4.8e-77 258.8 0.4 1.0 1 0 0 1 1 1 1 F-actin capping protein, beta subunit F-actin_cap_A PF01267.17 CBK22720.2 - 0.00062 19.3 0.5 0.0015 18.0 0.5 1.8 1 1 0 1 1 1 1 F-actin capping protein alpha subunit ABC_transp_aux PF09822.9 CBK22720.2 - 0.0017 17.8 0.0 0.0022 17.5 0.0 1.3 1 0 0 1 1 1 1 ABC-type uncharacterized transport system Alpha_E2_glycop PF00943.19 CBK22720.2 - 0.14 10.9 0.0 0.43 9.3 0.0 1.7 2 0 0 2 2 2 0 Alphavirus E2 glycoprotein Peptidase_C13 PF01650.18 CBK22721.2 - 8.3e-49 166.4 0.1 1.3e-48 165.7 0.1 1.3 1 0 0 1 1 1 1 Peptidase C13 family HTH_24 PF13412.6 CBK22721.2 - 0.075 12.6 0.0 0.15 11.7 0.0 1.5 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding ABC_tran PF00005.27 CBK22723.2 - 1.5e-29 103.2 0.0 2.5e-29 102.5 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 CBK22723.2 - 2.2e-07 31.0 1.9 0.00066 19.6 0.1 2.3 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 CBK22723.2 - 0.00026 21.4 0.0 0.00036 20.9 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain SMC_N PF02463.19 CBK22723.2 - 0.0004 19.9 0.6 0.24 10.8 0.0 2.2 1 1 1 2 2 2 2 RecF/RecN/SMC N terminal domain RNA12 PF10443.9 CBK22723.2 - 0.0032 16.3 0.0 0.0044 15.8 0.0 1.1 1 0 0 1 1 1 1 RNA12 protein T2SSE PF00437.20 CBK22723.2 - 0.02 14.0 0.0 0.029 13.4 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_29 PF13555.6 CBK22723.2 - 0.02 14.6 0.1 0.044 13.5 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain SbcCD_C PF13558.6 CBK22723.2 - 0.022 15.0 0.1 0.43 10.8 0.1 2.3 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit RsgA_GTPase PF03193.16 CBK22723.2 - 0.05 13.5 0.0 0.1 12.5 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase NACHT PF05729.12 CBK22723.2 - 0.054 13.4 0.1 0.16 11.9 0.0 1.9 2 0 0 2 2 2 0 NACHT domain AAA_30 PF13604.6 CBK22723.2 - 0.083 12.6 0.0 0.11 12.2 0.0 1.4 1 1 0 1 1 1 0 AAA domain AAA_23 PF13476.6 CBK22723.2 - 0.11 13.0 0.7 0.23 12.0 0.4 1.7 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 CBK22723.2 - 0.11 12.9 0.1 21 5.6 0.0 2.3 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 CBK22723.2 - 0.16 12.2 1.0 2 8.7 1.0 2.3 1 1 0 1 1 1 0 AAA domain DUF4238 PF14022.6 CBK22724.2 - 0.008 15.7 0.4 0.011 15.3 0.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4238) Syntaxin-6_N PF09177.11 CBK22724.2 - 0.016 15.7 5.5 0.094 13.3 5.5 1.9 1 1 0 1 1 1 0 Syntaxin 6, N-terminal ISG65-75 PF11727.8 CBK22724.2 - 0.028 13.7 0.2 0.034 13.4 0.2 1.1 1 0 0 1 1 1 0 Invariant surface glycoprotein Cep3 PF16846.5 CBK22724.2 - 0.056 11.9 2.1 0.072 11.5 2.1 1.0 1 0 0 1 1 1 0 Centromere DNA-binding protein complex CBF3 subunit B Hc1 PF07432.13 CBK22724.2 - 0.15 12.5 0.7 0.84 10.0 0.1 2.1 2 0 0 2 2 2 0 Histone H1-like protein Hc1 DUF3552 PF12072.8 CBK22724.2 - 2.8 7.3 6.9 0.33 10.4 0.8 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF3552) AcetylCoA_hyd_C PF13336.6 CBK22725.2 - 1.2e-62 210.4 0.0 1.8e-62 209.8 0.0 1.3 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain AcetylCoA_hydro PF02550.15 CBK22725.2 - 9.2e-21 74.7 0.0 1.6e-20 74.0 0.0 1.4 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase N-terminal domain polyprenyl_synt PF00348.17 CBK22726.2 - 6e-70 235.2 0.0 7.5e-70 234.9 0.0 1.0 1 0 0 1 1 1 1 Polyprenyl synthetase Thioredoxin PF00085.20 CBK22727.2 - 1.2e-36 124.9 0.0 2.6e-26 91.6 0.0 3.9 4 0 0 4 4 4 2 Thioredoxin Thioredoxin_6 PF13848.6 CBK22727.2 - 6.4e-26 91.4 4.4 1.1e-19 71.1 0.6 3.6 4 0 0 4 4 4 2 Thioredoxin-like domain Thioredoxin_2 PF13098.6 CBK22727.2 - 3.9e-13 49.8 0.3 1.1e-08 35.5 0.0 4.0 3 2 0 3 3 3 2 Thioredoxin-like domain OST3_OST6 PF04756.13 CBK22727.2 - 1.5e-07 31.1 0.0 3.3e-05 23.4 0.0 2.5 2 0 0 2 2 2 2 OST3 / OST6 family, transporter family Thioredoxin_7 PF13899.6 CBK22727.2 - 3.9e-05 23.7 0.2 0.00057 20.0 0.0 2.9 3 1 0 3 3 3 1 Thioredoxin-like AhpC-TSA PF00578.21 CBK22727.2 - 0.00021 21.2 0.3 0.13 12.1 0.0 3.1 2 1 1 3 3 3 2 AhpC/TSA family Redoxin PF08534.10 CBK22727.2 - 0.0097 15.6 0.1 1.2 8.9 0.0 2.8 3 0 0 3 3 3 1 Redoxin Thioredoxin_8 PF13905.6 CBK22727.2 - 0.05 13.9 0.1 1.2 9.5 0.0 3.1 2 1 0 2 2 2 0 Thioredoxin-like MCM PF00493.23 CBK22729.2 - 7.7e-101 335.9 0.0 1.4e-100 335.1 0.0 1.4 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 CBK22729.2 - 5.4e-25 87.7 1.7 9.7e-25 86.8 1.7 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 CBK22729.2 - 5.2e-19 68.5 0.3 1.4e-18 67.1 0.3 1.8 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 CBK22729.2 - 4.2e-07 30.5 0.3 1.1e-06 29.2 0.3 1.7 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 CBK22729.2 - 8e-07 28.6 0.0 0.00012 21.5 0.0 2.3 1 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 CBK22729.2 - 5.8e-05 23.1 0.0 0.0002 21.4 0.0 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_lid_2 PF17863.1 CBK22729.2 - 8.1e-05 22.4 0.5 0.00021 21.0 0.5 1.6 1 0 0 1 1 1 1 AAA lid domain TPR_11 PF13414.6 CBK22729.2 - 0.0028 17.3 0.0 0.0063 16.2 0.0 1.7 1 0 0 1 1 1 1 TPR repeat TPR_2 PF07719.17 CBK22729.2 - 0.0045 17.0 0.1 0.019 15.1 0.0 2.2 2 0 0 2 2 1 1 Tetratricopeptide repeat Sigma54_activat PF00158.26 CBK22729.2 - 0.014 15.2 0.0 0.52 10.0 0.0 2.3 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_3 PF07726.11 CBK22729.2 - 0.04 13.8 0.0 0.11 12.3 0.0 1.8 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 CBK22729.2 - 0.055 13.8 0.1 0.24 11.8 0.1 2.2 1 1 0 1 1 1 0 AAA ATPase domain TetR_C_20 PF17925.1 CBK22729.2 - 0.064 13.6 0.4 0.2 12.0 0.3 1.8 2 0 0 2 2 1 0 Tetracyclin repressor-like, C-terminal domain AAA PF00004.29 CBK22729.2 - 0.15 12.5 0.0 0.44 11.0 0.0 1.8 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Mon2_C PF16206.5 CBK22729.2 - 0.15 10.2 0.0 0.22 9.6 0.0 1.1 1 0 0 1 1 1 0 C-terminal region of Mon2 protein Metallophos PF00149.28 CBK22730.2 - 2.1e-28 100.2 0.0 3.1e-28 99.7 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase PPP5 PF08321.12 CBK22730.2 - 7.7e-20 71.0 0.1 1.9e-19 69.7 0.1 1.7 2 0 0 2 2 1 1 PPP5 TPR repeat region TPR_1 PF00515.28 CBK22730.2 - 2e-10 40.0 0.5 5.1e-09 35.6 0.1 2.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 CBK22730.2 - 4.2e-09 35.8 0.2 3.9e-08 32.8 0.1 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 CBK22730.2 - 3.6e-07 29.9 0.1 1.4e-06 28.0 0.1 2.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.6 CBK22730.2 - 0.0014 18.3 0.0 0.043 13.5 0.0 2.7 3 0 0 3 3 3 1 TPR repeat TPR_14 PF13428.6 CBK22730.2 - 0.0048 17.6 0.0 0.012 16.4 0.0 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_6 PF13174.6 CBK22730.2 - 0.01 16.4 0.2 0.022 15.4 0.2 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_12 PF13424.6 CBK22730.2 - 0.018 15.3 0.0 0.034 14.4 0.0 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_10 PF13374.6 CBK22730.2 - 0.031 14.2 0.0 0.059 13.3 0.0 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_9 PF13371.6 CBK22730.2 - 0.035 14.3 0.0 0.061 13.5 0.0 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_7 PF13176.6 CBK22730.2 - 0.036 14.1 0.0 0.094 12.8 0.0 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat SHNi-TPR PF10516.9 CBK22730.2 - 0.048 13.1 0.1 0.11 11.9 0.1 1.6 1 0 0 1 1 1 0 SHNi-TPR ANAPC3 PF12895.7 CBK22730.2 - 0.063 13.5 0.1 0.15 12.3 0.1 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 Fis1_TPR_C PF14853.6 CBK22730.2 - 0.085 12.9 0.2 0.2 11.8 0.2 1.5 1 0 0 1 1 1 0 Fis1 C-terminal tetratricopeptide repeat TAtT PF16811.5 CBK22730.2 - 0.1 11.9 0.0 0.15 11.4 0.0 1.1 1 0 0 1 1 1 0 TRAP transporter T-component PEPCK_ATP PF01293.20 CBK22731.2 - 1.5e-212 706.3 0.0 1.8e-212 706.1 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase SAM_2 PF07647.17 CBK22732.2 - 2.8e-07 30.5 1.1 1e-05 25.6 0.1 2.5 1 1 1 2 2 2 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 CBK22732.2 - 3.6e-06 27.3 1.8 0.00019 21.8 0.1 2.4 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) NCD1 PF04904.13 CBK22732.2 - 0.029 14.4 0.3 2.4 8.2 0.1 2.4 2 0 0 2 2 2 0 NAB conserved region 1 (NCD1) RNA_pol_A_CTD PF03118.15 CBK22732.2 - 0.073 12.8 0.0 0.19 11.5 0.0 1.7 1 0 0 1 1 1 0 Bacterial RNA polymerase, alpha chain C terminal domain Mrr_N PF14338.6 CBK22732.2 - 0.087 13.0 0.1 13 6.0 0.0 2.3 2 0 0 2 2 2 0 Mrr N-terminal domain Glyco_hyd_65N_2 PF14498.6 CBK22732.2 - 0.22 11.4 0.0 0.27 11.1 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 65, N-terminal domain Ank_2 PF12796.7 CBK22733.2 - 2.3e-23 82.6 0.1 1.3e-13 51.4 0.0 3.4 3 0 0 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 CBK22733.2 - 4.8e-20 69.5 1.4 1.2e-05 25.3 0.0 5.4 6 0 0 6 6 6 4 Ankyrin repeat Ank_5 PF13857.6 CBK22733.2 - 8.5e-20 70.6 0.6 1.5e-09 37.9 0.0 4.8 3 1 1 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 CBK22733.2 - 1.1e-19 69.9 0.1 1.5e-05 25.2 0.0 5.4 5 0 0 5 5 5 4 Ankyrin repeat Ank_4 PF13637.6 CBK22733.2 - 8.8e-16 58.1 0.2 3.7e-08 33.8 0.0 4.8 3 1 2 5 5 5 4 Ankyrin repeats (many copies) Methyltransf_8 PF05148.15 CBK22733.2 - 0.022 14.6 0.0 0.038 13.8 0.0 1.2 1 0 0 1 1 1 0 Hypothetical methyltransferase L51_S25_CI-B8 PF05047.16 CBK22735.2 - 1.6e-09 37.5 0.0 2.3e-09 37.0 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain DUF384 PF04064.13 CBK22735.2 - 0.069 13.0 0.6 0.19 11.6 0.6 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF384) ERGIC_N PF13850.6 CBK22736.2 - 9.9e-26 89.9 1.6 1.8e-25 89.1 1.6 1.5 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Thioredoxin PF00085.20 CBK22736.2 - 5.4e-18 64.9 0.0 9.1e-18 64.1 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin OST3_OST6 PF04756.13 CBK22736.2 - 2.2e-06 27.2 0.0 4.4e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family COPIIcoated_ERV PF07970.12 CBK22736.2 - 8.7e-05 22.5 0.2 0.00044 20.2 0.0 2.1 2 0 0 2 2 2 1 Endoplasmic reticulum vesicle transporter Thioredox_DsbH PF03190.15 CBK22736.2 - 0.00059 19.8 0.0 0.00095 19.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF255 Thioredoxin_7 PF13899.6 CBK22736.2 - 0.0032 17.6 0.2 0.0068 16.6 0.2 1.6 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.6 CBK22736.2 - 0.0051 17.3 0.0 0.0086 16.5 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 CBK22736.2 - 0.16 12.3 0.3 0.71 10.2 0.0 2.1 2 1 1 3 3 3 0 Thioredoxin-like RCC1 PF00415.18 CBK22737.2 - 4.3e-71 235.4 14.7 7e-15 55.4 0.0 6.5 7 0 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 CBK22737.2 - 1.9e-38 129.5 28.4 8.8e-09 34.9 0.3 7.2 7 0 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat SIS_2 PF13580.6 CBK22737.2 - 0.064 13.3 0.2 0.47 10.5 0.0 2.5 3 0 0 3 3 3 0 SIS domain SUKH-3 PF14433.6 CBK22737.2 - 0.19 12.2 2.2 28 5.2 0.0 3.7 3 2 1 5 5 5 0 SUKH-3 immunity protein Kdo PF06293.14 CBK22738.2 - 0.13 11.6 0.1 0.15 11.4 0.1 1.1 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Vps52 PF04129.12 CBK22739.2 - 1.1e-39 136.5 1.0 1.1e-39 136.5 1.0 2.1 1 1 1 2 2 2 1 Vps52 / Sac2 family Acetate_kinase PF00871.17 CBK22739.2 - 0.13 10.9 2.5 0.38 9.4 0.2 2.1 2 0 0 2 2 2 0 Acetokinase family Cytochrom_B562 PF07361.11 CBK22739.2 - 0.5 11.0 9.3 2 9.1 1.7 3.1 3 0 0 3 3 3 0 Cytochrome b562 PHD PF00628.29 CBK22740.2 - 4.7e-07 29.6 11.2 5.1e-06 26.3 11.2 2.3 1 1 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 CBK22740.2 - 0.0097 15.4 0.5 0.0097 15.4 0.5 2.5 2 0 0 2 2 2 1 PHD-finger zf-PHD-like PF15446.6 CBK22740.2 - 0.025 14.2 1.6 0.025 14.2 1.6 1.9 2 0 0 2 2 2 0 PHD/FYVE-zinc-finger like domain RFX5_DNA_bdg PF14621.6 CBK22740.2 - 0.041 13.7 1.3 0.041 13.7 1.3 2.0 1 1 1 2 2 2 0 RFX5 DNA-binding domain PHD_3 PF13922.6 CBK22740.2 - 0.73 10.3 3.6 0.29 11.5 0.2 2.0 2 0 0 2 2 2 0 PHD domain of transcriptional enhancer, Asx zf-HC5HC2H_2 PF13832.6 CBK22741.2 - 3.5e-23 81.9 5.4 7e-23 80.9 5.4 1.5 1 0 0 1 1 1 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 CBK22741.2 - 1.2e-19 70.3 1.8 1.2e-19 70.3 1.8 2.7 2 0 0 2 2 2 1 PHD-like zinc-binding domain Zf_RING PF16744.5 CBK22741.2 - 3.4 7.8 10.5 1.8 8.8 1.5 2.5 2 0 0 2 2 2 0 KIAA1045 RING finger zf-MIZ PF02891.20 CBK22742.2 - 4.1e-15 55.3 0.6 6.6e-15 54.6 0.6 1.4 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-Nse PF11789.8 CBK22742.2 - 9.5e-07 28.5 1.2 1.7e-06 27.7 1.2 1.4 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.6 CBK22742.2 - 0.066 13.3 1.3 9.8 6.3 0.2 2.5 2 0 0 2 2 2 0 RING-type zinc-finger zf-RING_2 PF13639.6 CBK22742.2 - 0.18 12.2 3.4 0.4 11.1 3.4 1.6 1 0 0 1 1 1 0 Ring finger domain Pribosyltran_N PF13793.6 CBK22743.2 - 4.3e-37 126.6 0.2 1.1e-36 125.2 0.1 1.8 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.6 CBK22743.2 - 3.8e-15 56.4 0.1 6.5e-15 55.6 0.1 1.3 1 0 0 1 1 1 1 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.27 CBK22743.2 - 0.00089 18.8 0.0 0.002 17.6 0.0 1.6 1 0 0 1 1 1 1 Phosphoribosyl transferase domain Carb_kinase PF01256.17 CBK22743.2 - 0.12 11.9 0.0 0.18 11.3 0.0 1.3 1 0 0 1 1 1 0 Carbohydrate kinase Cation_efflux PF01545.21 CBK22744.2 - 5.5e-42 143.8 7.0 7.3e-42 143.4 7.0 1.2 1 0 0 1 1 1 1 Cation efflux family PNISR PF15996.5 CBK22744.2 - 7 6.9 5.2 10 6.3 5.2 1.2 1 0 0 1 1 1 0 Arginine/serine-rich protein PNISR Tmemb_cc2 PF10267.9 CBK22744.2 - 7.2 5.6 8.0 10 5.1 8.0 1.1 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein Peptidase_C1 PF00112.23 CBK22745.2 - 3.8e-56 190.6 9.6 4.7e-56 190.3 9.6 1.1 1 0 0 1 1 1 1 Papain family cysteine protease CAMSAP_CKK PF08683.11 CBK22745.2 - 0.12 12.5 0.1 0.21 11.7 0.1 1.4 1 0 0 1 1 1 0 Microtubule-binding calmodulin-regulated spectrin-associated Reprolysin_5 PF13688.6 CBK22746.2 - 3.9e-06 27.2 0.0 6.8e-06 26.4 0.0 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.6 CBK22746.2 - 0.00044 20.8 0.0 0.00087 19.8 0.0 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.24 CBK22746.2 - 0.0029 17.4 0.0 0.0053 16.6 0.0 1.3 1 0 0 1 1 1 1 Matrixin Reprolysin_2 PF13574.6 CBK22746.2 - 0.015 15.2 0.0 0.027 14.3 0.0 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 CBK22746.2 - 0.083 12.5 0.0 0.18 11.4 0.0 1.5 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M66 PF10462.9 CBK22746.2 - 0.1 11.5 0.1 0.18 10.7 0.1 1.3 1 0 0 1 1 1 0 Peptidase M66 DUF2615 PF11027.8 CBK22746.2 - 6.2 7.0 6.2 1.4 9.1 1.0 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2615) RMI1_N PF08585.12 CBK22747.2 - 2.5e-19 69.9 0.0 4.4e-19 69.1 0.0 1.4 1 0 0 1 1 1 1 RecQ mediated genome instability protein HSP70 PF00012.20 CBK22748.2 - 3.5e-88 296.3 0.3 4.4e-88 296.0 0.3 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 CBK22748.2 - 1.6e-11 43.6 0.1 2.7e-05 23.2 0.0 3.3 2 1 0 3 3 3 3 MreB/Mbl protein StbA PF06406.11 CBK22748.2 - 0.075 12.3 0.1 0.75 9.0 0.0 2.3 1 1 1 2 2 2 0 StbA protein RNA_pol_A_bac PF01000.26 CBK22749.2 - 2.4e-21 76.2 0.0 6.4e-21 74.8 0.0 1.7 2 0 0 2 2 2 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.24 CBK22749.2 - 4.9e-18 64.3 0.0 7.4e-18 63.8 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Fer4_9 PF13187.6 CBK22749.2 - 0.021 15.0 0.6 0.046 13.9 0.6 1.5 1 0 0 1 1 1 0 4Fe-4S dicluster domain Fer4_7 PF12838.7 CBK22749.2 - 0.023 15.3 0.9 0.053 14.1 0.9 1.6 1 0 0 1 1 1 0 4Fe-4S dicluster domain Fer4 PF00037.27 CBK22749.2 - 0.19 11.6 2.3 0.22 11.4 0.8 1.9 2 0 0 2 2 2 0 4Fe-4S binding domain AAA_5 PF07728.14 CBK22750.2 - 9.6e-124 407.9 0.0 5.9e-22 78.2 0.0 10.1 10 0 0 10 10 9 9 AAA domain (dynein-related subfamily) AAA_lid_7 PF17867.1 CBK22750.2 - 1.3e-38 131.4 11.9 8.5e-14 51.6 0.1 7.0 6 0 0 6 6 6 3 Midasin AAA lid domain AAA_3 PF07726.11 CBK22750.2 - 1.3e-32 112.4 0.0 9.5e-10 38.4 0.0 8.9 8 0 0 8 8 8 4 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 CBK22750.2 - 2.6e-28 98.8 1.2 0.0001 21.9 0.0 6.7 6 0 0 6 6 6 6 P-loop containing dynein motor region AAA_lid_5 PF17865.1 CBK22750.2 - 3.4e-27 94.6 0.0 1.5e-26 92.5 0.0 2.3 1 0 0 1 1 1 1 Midasin AAA lid domain AAA_16 PF13191.6 CBK22750.2 - 4.5e-25 89.0 8.4 0.00046 20.6 0.0 8.9 8 1 0 8 8 7 6 AAA ATPase domain AAA PF00004.29 CBK22750.2 - 6.6e-25 88.1 0.0 9.5e-05 22.8 0.0 7.5 6 0 0 6 6 6 4 ATPase family associated with various cellular activities (AAA) Dynein_heavy PF03028.15 CBK22750.2 - 6.2e-20 71.5 0.0 0.0088 16.1 0.0 7.2 6 0 0 6 6 6 4 Dynein heavy chain region D6 P-loop domain AAA_22 PF13401.6 CBK22750.2 - 1.5e-17 64.2 3.3 0.067 13.5 0.0 7.9 8 0 0 8 8 6 4 AAA domain AAA_14 PF13173.6 CBK22750.2 - 2.2e-16 60.1 1.1 0.012 15.6 0.0 8.1 9 0 0 9 9 7 3 AAA domain AAA_6 PF12774.7 CBK22750.2 - 1.5e-15 57.0 1.9 0.1 11.5 0.0 9.0 10 0 0 10 10 10 3 Hydrolytic ATP binding site of dynein motor region T2SSE PF00437.20 CBK22750.2 - 4.1e-15 55.6 0.0 0.095 11.7 0.0 6.8 7 0 0 7 7 7 4 Type II/IV secretion system protein Sigma54_activat PF00158.26 CBK22750.2 - 5.4e-15 55.5 0.1 0.063 13.0 0.1 6.7 6 0 0 6 6 6 2 Sigma-54 interaction domain NACHT PF05729.12 CBK22750.2 - 4e-14 52.9 2.5 0.15 12.0 0.0 7.1 7 0 0 7 7 6 4 NACHT domain TsaE PF02367.17 CBK22750.2 - 1.8e-13 50.6 3.5 0.36 10.8 0.0 6.2 6 0 0 6 6 6 5 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_30 PF13604.6 CBK22750.2 - 5.2e-13 49.1 0.0 0.024 14.4 0.0 7.2 7 1 0 7 7 6 2 AAA domain AAA_33 PF13671.6 CBK22750.2 - 1.5e-12 47.8 0.0 0.51 10.5 0.0 7.0 6 0 0 6 6 6 1 AAA domain AAA_29 PF13555.6 CBK22750.2 - 4.8e-12 45.4 0.3 0.12 12.2 0.0 6.4 7 0 0 7 7 6 2 P-loop containing region of AAA domain RNA_helicase PF00910.22 CBK22750.2 - 1.8e-11 44.4 0.5 1.5 9.3 0.0 6.7 6 0 0 6 6 6 2 RNA helicase Mg_chelatase PF01078.21 CBK22750.2 - 6.5e-11 42.0 0.9 6 6.2 0.0 9.3 10 0 0 10 10 10 0 Magnesium chelatase, subunit ChlI ABC_tran PF00005.27 CBK22750.2 - 7.2e-11 42.8 23.1 0.0077 16.7 0.0 8.8 8 0 0 8 8 6 3 ABC transporter AAA_19 PF13245.6 CBK22750.2 - 9.5e-11 42.2 0.5 0.91 9.9 0.0 6.4 6 0 0 6 6 6 3 AAA domain Sigma54_activ_2 PF14532.6 CBK22750.2 - 1.7e-10 41.2 0.7 0.15 12.2 0.0 7.1 6 0 0 6 6 6 1 Sigma-54 interaction domain Viral_helicase1 PF01443.18 CBK22750.2 - 5.3e-09 36.2 0.1 0.013 15.2 0.0 5.6 5 0 0 5 5 5 1 Viral (Superfamily 1) RNA helicase AAA_18 PF13238.6 CBK22750.2 - 1.1e-08 35.7 13.6 1.1 9.8 0.0 8.7 7 1 0 7 7 6 2 AAA domain RuvB_N PF05496.12 CBK22750.2 - 1.6e-08 34.5 0.9 0.23 11.2 0.0 6.5 7 0 0 7 7 7 1 Holliday junction DNA helicase RuvB P-loop domain Rad17 PF03215.15 CBK22750.2 - 1.9e-07 31.2 8.5 0.67 9.9 0.1 6.8 7 0 0 7 7 6 2 Rad17 P-loop domain DUF815 PF05673.13 CBK22750.2 - 2.4e-07 30.2 0.1 0.68 9.0 0.0 6.1 6 0 0 6 6 6 1 Protein of unknown function (DUF815) RsgA_GTPase PF03193.16 CBK22750.2 - 6e-07 29.5 0.2 1.4 8.8 0.0 6.1 6 0 0 6 6 6 1 RsgA GTPase IstB_IS21 PF01695.17 CBK22750.2 - 1e-06 28.6 0.0 2.1 8.1 0.0 6.2 6 0 0 6 6 6 1 IstB-like ATP binding protein AAA_25 PF13481.6 CBK22750.2 - 1.8e-06 27.6 0.8 11 5.6 0.0 6.4 7 0 0 7 7 7 0 AAA domain AAA_8 PF12780.7 CBK22750.2 - 6e-06 25.8 5.6 1.6 8.0 0.0 6.9 8 0 0 8 8 7 1 P-loop containing dynein motor region D4 MCM PF00493.23 CBK22750.2 - 1.9e-05 23.9 0.1 0.28 10.2 0.0 5.5 7 0 0 7 7 7 1 MCM P-loop domain SRP54 PF00448.22 CBK22750.2 - 3.3e-05 23.6 1.1 11 5.5 0.0 5.6 6 0 0 6 6 6 0 SRP54-type protein, GTPase domain PduV-EutP PF10662.9 CBK22750.2 - 4.4e-05 23.3 6.1 2.3 7.9 0.1 5.6 6 0 0 6 6 6 1 Ethanolamine utilisation - propanediol utilisation AAA_28 PF13521.6 CBK22750.2 - 5.1e-05 23.6 16.6 2 8.6 0.0 7.6 7 0 0 7 7 6 1 AAA domain NTPase_1 PF03266.15 CBK22750.2 - 0.00011 22.1 2.5 7.8 6.4 0.1 4.9 5 0 0 5 5 4 0 NTPase Bac_DnaA PF00308.18 CBK22750.2 - 0.0002 21.3 0.6 14 5.4 0.0 5.1 5 0 0 5 5 5 0 Bacterial dnaA protein SRPRB PF09439.10 CBK22750.2 - 0.001 18.5 0.6 2.6 7.5 0.0 4.8 5 0 0 5 5 4 1 Signal recognition particle receptor beta subunit DEAD PF00270.29 CBK22750.2 - 0.0011 18.8 0.0 22 4.8 0.0 4.7 5 0 0 5 5 4 0 DEAD/DEAH box helicase ATP-synt_ab PF00006.25 CBK22750.2 - 0.0059 16.3 0.0 11 5.6 0.0 3.6 4 0 0 4 4 3 0 ATP synthase alpha/beta family, nucleotide-binding domain MMR_HSR1 PF01926.23 CBK22750.2 - 0.018 15.1 1.3 60 3.8 0.0 5.6 6 0 0 6 6 4 0 50S ribosome-binding GTPase PRK PF00485.18 CBK22750.2 - 0.027 14.2 0.2 14 5.4 0.0 4.3 4 0 0 4 4 4 0 Phosphoribulokinase / Uridine kinase family CelTOS PF18659.1 CBK22750.2 - 0.052 14.0 0.3 0.4 11.1 0.1 2.7 2 0 0 2 2 1 0 Cell-traversal protein for ookinetes and sporozoites FtsK_SpoIIIE PF01580.18 CBK22750.2 - 0.091 12.1 3.0 30 3.8 0.0 4.3 4 0 0 4 4 3 0 FtsK/SpoIIIE family Fanconi_A PF03511.14 CBK22750.2 - 0.11 12.5 0.2 1.8 8.5 0.0 3.3 4 0 0 4 4 1 0 Fanconi anaemia group A protein Roc PF08477.13 CBK22750.2 - 0.43 10.8 6.7 1.4e+02 2.7 0.1 5.8 6 0 0 6 6 6 0 Ras of Complex, Roc, domain of DAPkinase TPR_MLP1_2 PF07926.12 CBK22751.2 - 0.00098 19.2 6.8 0.00098 19.2 6.8 5.7 4 1 1 5 5 5 3 TPR/MLP1/MLP2-like protein MAD PF05557.13 CBK22751.2 - 0.0023 16.4 46.3 0.0023 16.4 46.3 3.1 2 1 0 3 3 3 2 Mitotic checkpoint protein XLF PF09302.11 CBK22751.2 - 0.0027 17.9 13.5 0.0027 17.9 13.5 3.9 1 1 4 5 5 5 1 XLF-Cernunnos, XRcc4-like factor, NHEJ component Rootletin PF15035.6 CBK22751.2 - 0.0052 16.8 18.6 0.0052 16.8 18.6 4.6 2 2 1 3 3 1 1 Ciliary rootlet component, centrosome cohesion Filament PF00038.21 CBK22751.2 - 0.0069 16.0 6.5 0.0069 16.0 6.5 5.5 1 1 2 4 4 4 3 Intermediate filament protein AAA_13 PF13166.6 CBK22751.2 - 0.018 13.7 64.7 0.018 13.7 17.3 3.5 1 1 2 3 3 3 0 AAA domain PKcGMP_CC PF16808.5 CBK22751.2 - 0.083 12.8 0.4 0.083 12.8 0.4 4.5 5 1 0 5 5 5 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Paralemmin PF03285.15 CBK22751.2 - 0.16 11.5 0.0 0.16 11.5 0.0 5.3 3 2 2 5 5 5 0 Paralemmin Spc7 PF08317.11 CBK22751.2 - 0.37 9.6 86.9 0.37 9.6 8.1 5.3 2 2 3 5 5 5 0 Spc7 kinetochore protein DUF2935 PF11155.8 CBK22751.2 - 0.89 9.9 19.2 1.8e+04 -6.3 19.2 5.0 1 1 0 1 1 0 0 Domain of unknown function (DUF2935) DUF1664 PF07889.12 CBK22751.2 - 2.7 8.1 55.2 2 8.5 1.9 6.8 3 2 3 7 7 7 0 Protein of unknown function (DUF1664) Syntaxin PF00804.25 CBK22751.2 - 3.3 7.3 65.0 0.36 10.5 18.7 5.4 1 1 5 6 6 6 0 Syntaxin Syntaxin_2 PF14523.6 CBK22751.2 - 4.3 7.8 63.3 0.093 13.1 2.1 6.6 2 2 4 6 6 6 0 Syntaxin-like protein FUSC PF04632.12 CBK22751.2 - 8.5 4.8 44.1 0.66 8.5 13.0 3.6 1 1 2 3 3 3 0 Fusaric acid resistance protein family Pkinase PF00069.25 CBK22752.2 - 1.1e-35 123.3 0.0 2.1e-35 122.4 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBK22752.2 - 1.5e-20 73.6 0.0 1.5e-19 70.3 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.11 CBK22752.2 - 0.0003 19.9 0.4 0.00043 19.4 0.4 1.1 1 0 0 1 1 1 1 Poxvirus serine/threonine protein kinase Pkinase_fungal PF17667.1 CBK22752.2 - 0.032 13.0 0.1 0.055 12.2 0.1 1.3 1 0 0 1 1 1 0 Fungal protein kinase YrbL-PhoP_reg PF10707.9 CBK22752.2 - 0.048 13.2 0.1 0.19 11.3 0.0 1.9 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL APH PF01636.23 CBK22752.2 - 0.22 11.4 0.1 0.46 10.4 0.1 1.4 2 0 0 2 2 2 0 Phosphotransferase enzyme family Ank_4 PF13637.6 CBK22753.2 - 7.6e-10 39.1 0.0 2e-08 34.6 0.0 2.6 2 1 1 3 3 3 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 CBK22753.2 - 1.3e-09 38.5 0.0 1.7e-07 31.7 0.0 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 CBK22753.2 - 1.1e-07 32.0 0.3 5.7e-05 23.3 0.1 3.2 2 1 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 CBK22753.2 - 3.2e-05 24.0 0.0 0.097 13.3 0.0 2.8 3 0 0 3 3 3 2 Ankyrin repeat Ank PF00023.30 CBK22753.2 - 6.9e-05 23.1 0.1 0.26 11.8 0.0 2.6 2 1 0 2 2 2 2 Ankyrin repeat Methyltr_RsmB-F PF01189.17 CBK22754.2 - 4.3e-28 98.3 0.0 5.3e-28 98.0 0.0 1.1 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F FtsJ PF01728.19 CBK22754.2 - 0.001 19.2 0.0 0.0027 17.9 0.0 1.6 1 1 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_31 PF13847.6 CBK22754.2 - 0.033 14.0 0.0 0.069 12.9 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain HSP20 PF00011.21 CBK22755.2 - 5.7e-27 93.9 2.3 6.8e-27 93.6 2.3 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 CBK22755.2 - 3e-13 49.1 0.0 5e-13 48.4 0.0 1.4 1 0 0 1 1 1 1 HSP20-like domain found in ArsA YqzE PF14038.6 CBK22755.2 - 0.72 9.9 2.6 0.99 9.5 0.3 2.4 3 0 0 3 3 3 0 YqzE-like protein HA2 PF04408.23 CBK22756.2 - 2.4e-21 76.0 0.0 5.8e-21 74.8 0.0 1.6 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 CBK22756.2 - 6.9e-14 52.0 0.0 1.4e-13 51.0 0.0 1.5 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 CBK22756.2 - 1.7e-13 50.9 0.0 1e-12 48.3 0.0 2.3 2 1 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 CBK22756.2 - 1.6e-08 34.5 0.6 1.4e-07 31.5 0.3 2.4 2 1 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.6 CBK22756.2 - 6.3e-06 26.5 0.1 1.8e-05 25.1 0.1 1.7 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 CBK22756.2 - 0.00046 20.0 0.0 0.00087 19.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain ResIII PF04851.15 CBK22756.2 - 0.0005 20.1 0.2 0.017 15.2 0.2 2.2 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_30 PF13604.6 CBK22756.2 - 0.0023 17.7 0.0 0.0038 17.0 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_23 PF13476.6 CBK22756.2 - 0.0037 17.8 0.2 0.017 15.7 0.1 1.9 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 CBK22756.2 - 0.018 15.4 0.0 0.041 14.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 CBK22756.2 - 0.046 13.5 0.0 0.11 12.2 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Flavi_DEAD PF07652.14 CBK22756.2 - 0.064 13.2 0.0 0.14 12.1 0.0 1.5 1 0 0 1 1 1 0 Flavivirus DEAD domain SRPRB PF09439.10 CBK22756.2 - 0.065 12.7 0.1 9.1 5.7 0.0 2.3 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit ABC_tran PF00005.27 CBK22756.2 - 0.073 13.6 0.8 0.38 11.3 0.2 2.2 1 1 0 2 2 2 0 ABC transporter T2SSE PF00437.20 CBK22756.2 - 0.093 11.8 0.0 0.17 11.0 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_7 PF12775.7 CBK22756.2 - 0.099 12.1 0.0 0.18 11.3 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region MCR_D PF02505.14 CBK22756.2 - 0.13 12.1 0.0 0.3 10.9 0.0 1.5 1 0 0 1 1 1 0 Methyl-coenzyme M reductase operon protein D DUF2075 PF09848.9 CBK22756.2 - 0.16 11.2 0.0 0.24 10.6 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) ACR_tran PF00873.19 CBK22757.2 - 0.08 10.6 0.0 0.13 9.9 0.0 1.2 1 0 0 1 1 1 0 AcrB/AcrD/AcrF family CBM64 PF18666.1 CBK22757.2 - 0.15 12.2 0.0 0.36 10.9 0.0 1.7 1 0 0 1 1 1 0 Carbohydrate-binding module 64 YbbR PF07949.12 CBK22759.2 - 0.12 12.7 0.2 0.59 10.5 0.0 2.1 2 0 0 2 2 2 0 YbbR-like protein TK PF00265.18 CBK22759.2 - 0.18 11.6 0.1 0.38 10.6 0.0 1.4 1 1 0 1 1 1 0 Thymidine kinase zf-rbx1 PF12678.7 CBK22762.2 - 8.3e-09 35.6 4.8 1.3e-08 35.0 4.8 1.3 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 CBK22762.2 - 3.2e-08 33.8 4.2 4.7e-08 33.2 4.2 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 CBK22762.2 - 2.9e-07 30.2 4.7 4.8e-07 29.5 4.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 CBK22762.2 - 3.1e-06 27.0 2.1 4.3e-06 26.5 2.1 1.2 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 CBK22762.2 - 6.4e-06 25.9 3.6 9.8e-06 25.3 3.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 CBK22762.2 - 2.5e-05 23.8 1.6 3.6e-05 23.3 1.6 1.3 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-C3HC4_3 PF13920.6 CBK22762.2 - 6.2e-05 22.8 1.4 9.3e-05 22.2 1.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CBK22762.2 - 8.8e-05 22.4 2.3 0.00013 21.8 2.3 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 CBK22762.2 - 0.00015 21.7 1.8 0.00015 21.7 1.8 1.8 1 1 1 2 2 2 1 RING-type zinc-finger zf-RING_11 PF17123.5 CBK22762.2 - 0.00045 19.9 1.1 0.001 18.8 1.1 1.6 1 0 0 1 1 1 1 RING-like zinc finger zf-ANAPC11 PF12861.7 CBK22762.2 - 0.00066 19.7 1.1 0.00091 19.2 1.1 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Rtf2 PF04641.12 CBK22762.2 - 0.0014 18.1 0.1 0.0015 18.0 0.1 1.2 1 0 0 1 1 1 1 Rtf2 RING-finger zf-RING-like PF08746.11 CBK22762.2 - 0.008 16.5 2.9 0.011 16.0 2.9 1.2 1 0 0 1 1 1 1 RING-like domain zf-C3HC4_4 PF15227.6 CBK22762.2 - 0.013 15.6 2.1 0.025 14.7 2.1 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING FANCL_C PF11793.8 CBK22762.2 - 0.014 15.6 3.0 0.1 12.8 3.1 2.0 1 1 0 1 1 1 0 FANCL C-terminal domain Fe-ADH PF00465.19 CBK22762.2 - 0.029 13.2 0.1 0.031 13.1 0.1 1.0 1 0 0 1 1 1 0 Iron-containing alcohol dehydrogenase zf-C3H2C3 PF17122.5 CBK22762.2 - 0.034 14.2 3.9 0.081 13.0 3.9 1.6 1 1 0 1 1 1 0 Zinc-finger RINGv PF12906.7 CBK22762.2 - 0.04 14.1 3.7 0.067 13.3 3.7 1.3 1 0 0 1 1 1 0 RING-variant domain Aminotran_1_2 PF00155.21 CBK22764.2 - 1.4e-37 129.8 0.0 1.8e-37 129.4 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 CBK22764.2 - 0.017 14.4 0.0 0.041 13.2 0.0 1.7 2 0 0 2 2 2 0 Beta-eliminating lyase ATP_bind_3 PF01171.20 CBK22766.2 - 2.7e-09 37.0 0.0 5.2e-09 36.1 0.0 1.5 1 1 0 1 1 1 1 PP-loop family tRNA_Me_trans PF03054.16 CBK22766.2 - 0.076 11.8 0.2 0.13 11.0 0.2 1.4 1 1 0 1 1 1 0 tRNA methyl transferase AAA PF00004.29 CBK22768.2 - 6.8e-44 149.5 0.0 1e-43 148.9 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CBK22768.2 - 2.2e-14 53.0 0.8 5e-14 51.8 0.8 1.6 1 0 0 1 1 1 1 AAA+ lid domain RuvB_N PF05496.12 CBK22768.2 - 2.1e-06 27.6 0.0 7.1e-06 25.8 0.0 1.8 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 CBK22768.2 - 7.1e-05 23.2 0.1 0.014 15.7 0.0 2.5 1 1 1 2 2 2 1 AAA ATPase domain TIP49 PF06068.13 CBK22768.2 - 0.00011 21.6 0.0 0.00018 20.8 0.0 1.2 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_5 PF07728.14 CBK22768.2 - 0.00043 20.3 0.0 0.0086 16.1 0.0 2.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 CBK22768.2 - 0.0021 18.2 0.0 0.0045 17.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) RNA_helicase PF00910.22 CBK22768.2 - 0.059 13.8 0.0 0.15 12.5 0.0 1.7 1 0 0 1 1 1 0 RNA helicase IstB_IS21 PF01695.17 CBK22768.2 - 0.062 13.0 0.0 0.098 12.4 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_7 PF12775.7 CBK22768.2 - 0.072 12.6 0.0 0.3 10.6 0.0 2.0 1 1 0 1 1 1 0 P-loop containing dynein motor region Mg_chelatase PF01078.21 CBK22768.2 - 0.088 12.2 0.1 0.23 10.8 0.0 1.7 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 CBK22768.2 - 0.1 12.5 0.0 0.24 11.3 0.0 1.7 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 CBK22768.2 - 0.11 12.8 0.0 0.94 9.7 0.0 2.3 1 1 0 1 1 1 0 AAA domain AAA_33 PF13671.6 CBK22768.2 - 0.12 12.5 0.0 0.26 11.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 CBK22768.2 - 0.13 12.3 0.0 0.24 11.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.15 CBK22768.2 - 0.13 12.2 0.0 0.24 11.3 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain GP41 PF00517.17 CBK22770.2 - 0.013 15.4 0.3 0.014 15.3 0.3 1.0 1 0 0 1 1 1 0 Retroviral envelope protein ELO PF01151.18 CBK22771.2 - 1.2e-60 205.2 22.6 1.2e-60 205.2 22.6 1.4 2 0 0 2 2 2 1 GNS1/SUR4 family HAP1_N PF04849.13 CBK22772.2 - 0.00043 19.6 11.5 0.0013 18.0 11.5 1.7 1 1 0 1 1 1 1 HAP1 N-terminal conserved region TPR_MLP1_2 PF07926.12 CBK22772.2 - 0.00063 19.8 8.7 0.0014 18.7 8.7 1.5 1 0 0 1 1 1 1 TPR/MLP1/MLP2-like protein Cep57_CLD_2 PF14197.6 CBK22772.2 - 0.011 15.8 4.5 0.011 15.8 4.5 2.8 2 1 0 2 2 2 0 Centrosome localisation domain of PPC89 TFIIA PF03153.13 CBK22772.2 - 0.013 15.5 12.5 0.017 15.2 12.5 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit ABC_tran_CTD PF16326.5 CBK22772.2 - 0.33 11.2 6.1 0.24 11.6 3.3 2.2 1 1 1 2 2 2 0 ABC transporter C-terminal domain Rho_Binding PF08912.11 CBK22772.2 - 0.42 11.5 7.8 0.48 11.3 1.1 2.5 2 0 0 2 2 2 0 Rho Binding SIKE PF05769.11 CBK22772.2 - 0.5 10.3 10.8 1.2 9.0 0.8 2.8 1 1 2 3 3 3 0 SIKE family BLOC1_2 PF10046.9 CBK22772.2 - 0.67 10.3 4.2 18 5.7 0.2 2.5 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DivIVA PF05103.13 CBK22772.2 - 0.69 10.0 6.6 0.19 11.8 2.3 2.1 1 1 1 2 2 2 0 DivIVA protein TSC22 PF01166.18 CBK22772.2 - 0.71 10.2 8.0 0.31 11.4 3.9 2.4 1 1 2 3 3 3 0 TSC-22/dip/bun family TMF_TATA_bd PF12325.8 CBK22772.2 - 0.74 10.1 8.7 2.6 8.3 8.2 2.2 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding UPF0242 PF06785.11 CBK22772.2 - 0.92 9.6 13.2 23 5.0 13.3 2.2 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus GIT_CC PF16559.5 CBK22772.2 - 1.1 9.2 6.9 3.6 7.5 0.2 3.5 4 0 0 4 4 4 0 GIT coiled-coil Rho guanine nucleotide exchange factor FapA PF03961.13 CBK22772.2 - 1.5 7.3 4.1 1.9 7.0 4.1 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A Geminin PF07412.12 CBK22772.2 - 1.7 8.4 11.0 0.48 10.1 3.5 2.3 1 1 1 2 2 2 0 Geminin DUF4106 PF13388.6 CBK22772.2 - 1.7 7.8 21.5 3 7.0 21.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) Cnn_1N PF07989.11 CBK22772.2 - 3.5 7.9 9.3 1.1 9.4 1.1 2.7 2 1 1 3 3 3 0 Centrosomin N-terminal motif 1 YabA PF06156.13 CBK22772.2 - 4.1 8.1 8.8 1.2 9.8 1.6 2.6 1 1 1 2 2 2 0 Initiation control protein YabA Ndc1_Nup PF09531.10 CBK22772.2 - 4.5 5.8 8.9 5.9 5.5 8.9 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup APG6_N PF17675.1 CBK22772.2 - 4.7 7.8 14.8 7.1 7.2 3.4 2.3 1 1 1 2 2 2 0 Apg6 coiled-coil region DivIC PF04977.15 CBK22772.2 - 6.2 6.7 10.9 1.3 8.8 2.2 2.6 1 1 1 2 2 2 0 Septum formation initiator DUF4407 PF14362.6 CBK22772.2 - 7.2 5.9 8.1 8.9 5.6 6.0 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) CCDC-167 PF15188.6 CBK22772.2 - 7.3 7.0 11.5 5.1 7.5 6.9 2.7 2 1 1 3 3 2 0 Coiled-coil domain-containing protein 167 ZapB PF06005.12 CBK22772.2 - 7.8 7.0 14.8 0.23 11.9 5.6 2.6 1 1 1 2 2 2 0 Cell division protein ZapB SOAR PF16533.5 CBK22772.2 - 8 6.5 10.5 2.1e+02 2.0 10.5 2.3 1 1 0 1 1 1 0 STIM1 Orai1-activating region Peptidase_C13 PF01650.18 CBK22774.2 - 4.2e-53 180.5 0.0 5.8e-53 180.0 0.0 1.2 1 0 0 1 1 1 1 Peptidase C13 family Peptidase_C13 PF01650.18 CBK22775.2 - 5.7e-53 180.0 0.0 8e-53 179.6 0.0 1.2 1 0 0 1 1 1 1 Peptidase C13 family DUF563 PF04577.14 CBK22776.2 - 0.022 14.9 0.0 0.049 13.8 0.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF563) DUF1394 PF07159.12 CBK22777.2 - 9.7e-11 41.5 0.0 1.4e-10 40.9 0.0 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF1394) Pkinase PF00069.25 CBK22779.2 - 2.1e-67 227.3 0.0 2.5e-67 227.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBK22779.2 - 3.2e-42 144.6 0.0 3.9e-42 144.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CBK22779.2 - 0.0002 20.8 0.0 0.002 17.5 0.0 2.1 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 CBK22779.2 - 0.0056 16.1 0.0 0.0089 15.4 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.11 CBK22779.2 - 0.011 14.8 0.0 0.017 14.2 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 RIO1 PF01163.22 CBK22779.2 - 0.022 14.4 0.2 0.066 12.8 0.2 1.6 1 1 1 2 2 2 0 RIO1 family APH PF01636.23 CBK22779.2 - 0.026 14.5 0.1 0.098 12.6 0.2 1.8 1 1 1 2 2 2 0 Phosphotransferase enzyme family ABC1 PF03109.16 CBK22779.2 - 0.039 14.1 0.1 0.43 10.8 0.0 2.2 2 0 0 2 2 2 0 ABC1 family Pkinase_fungal PF17667.1 CBK22779.2 - 0.08 11.7 0.0 0.11 11.2 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase Choline_kinase PF01633.20 CBK22779.2 - 0.15 11.6 0.7 0.2 11.2 0.1 1.5 2 0 0 2 2 2 0 Choline/ethanolamine kinase PRMT5 PF05185.16 CBK22780.2 - 6.5e-53 179.1 0.0 1.3e-52 178.1 0.0 1.5 2 0 0 2 2 2 1 PRMT5 arginine-N-methyltransferase PRMT5_C PF17286.2 CBK22780.2 - 3.8e-42 144.1 0.8 5.4e-42 143.6 0.8 1.2 1 0 0 1 1 1 1 PRMT5 oligomerisation domain Met_10 PF02475.16 CBK22780.2 - 0.012 15.4 0.0 0.015 15.0 0.0 1.3 1 0 0 1 1 1 0 Met-10+ like-protein Methyltransf_31 PF13847.6 CBK22780.2 - 0.027 14.3 0.0 0.044 13.6 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain UPF0020 PF01170.18 CBK22780.2 - 0.038 13.7 0.0 0.06 13.0 0.0 1.2 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 Methyltransf_25 PF13649.6 CBK22780.2 - 0.075 13.7 0.0 0.13 13.0 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain GTP_EFTU PF00009.27 CBK22781.2 - 2.1e-40 138.3 0.5 2.5e-40 138.1 0.5 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 CBK22781.2 - 1.2e-12 48.2 0.1 2.4e-12 47.1 0.1 1.6 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain MMR_HSR1 PF01926.23 CBK22781.2 - 0.0046 17.0 0.1 0.12 12.5 0.0 3.0 2 1 0 2 2 2 1 50S ribosome-binding GTPase THOC2_N PF16134.5 CBK22782.2 - 1.6e-21 76.7 4.5 9e-13 47.7 3.5 2.0 1 1 1 2 2 2 2 THO complex subunit 2 N-terminus RNA_pol_Rpb4 PF03874.16 CBK22782.2 - 0.0021 18.4 1.2 0.0029 17.9 1.2 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb4 RST PF12174.8 CBK22782.2 - 0.018 14.9 0.1 0.018 14.9 0.1 2.8 4 1 1 5 5 5 0 RCD1-SRO-TAF4 (RST) plant domain His_Me_b4a2 PF18275.1 CBK22782.2 - 0.048 13.7 0.3 0.091 12.8 0.3 1.4 1 0 0 1 1 1 0 His-Me finger endonuclease beta4-alpha2 domain Cpn60_TCP1 PF00118.24 CBK22783.2 - 1.6e-86 290.9 0.9 1.9e-86 290.7 0.9 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family IF4E PF01652.18 CBK22784.2 - 1.1e-13 51.2 1.4 6.6e-13 48.8 1.4 2.0 1 1 0 1 1 1 1 Eukaryotic initiation factor 4E Pkinase PF00069.25 CBK22785.2 - 5e-41 140.8 0.0 7.2e-41 140.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBK22785.2 - 1.2e-16 60.8 0.0 1.9e-16 60.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CBK22785.2 - 9.1e-11 41.6 0.0 3.5e-08 33.1 0.0 2.4 1 1 1 2 2 2 2 Kinase-like APH PF01636.23 CBK22785.2 - 3.5e-09 36.9 2.6 0.00043 20.3 0.0 2.6 2 1 1 3 3 3 2 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 CBK22785.2 - 3.3e-07 29.4 7.6 3.6e-07 29.3 0.0 2.7 2 1 0 2 2 2 1 Fungal protein kinase Kdo PF06293.14 CBK22785.2 - 7.7e-07 28.7 0.0 1.4e-06 27.8 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 CBK22785.2 - 0.014 15.0 0.0 0.059 13.0 0.0 1.9 2 0 0 2 2 2 0 RIO1 family YrbL-PhoP_reg PF10707.9 CBK22785.2 - 0.043 13.3 1.4 0.19 11.2 0.0 2.5 3 0 0 3 3 3 0 PhoP regulatory network protein YrbL DHDPS PF00701.22 CBK22785.2 - 0.16 10.7 0.0 0.27 9.9 0.0 1.2 1 0 0 1 1 1 0 Dihydrodipicolinate synthetase family TPR_19 PF14559.6 CBK22786.2 - 0.018 15.6 0.1 0.051 14.1 0.1 1.8 1 1 0 1 1 1 0 Tetratricopeptide repeat DUF4201 PF13870.6 CBK22787.2 - 0.0021 17.8 71.4 0.035 13.8 8.9 4.2 1 1 3 4 4 4 3 Domain of unknown function (DUF4201) CENP-F_leu_zip PF10473.9 CBK22787.2 - 0.0099 15.9 21.0 0.0099 15.9 21.0 5.0 1 1 3 4 4 4 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TMF_DNA_bd PF12329.8 CBK22787.2 - 0.02 14.9 6.5 0.02 14.9 6.5 7.2 2 1 4 7 7 7 0 TATA element modulatory factor 1 DNA binding Spc7 PF08317.11 CBK22787.2 - 0.032 13.1 86.1 0.21 10.4 25.0 4.2 1 1 3 4 4 4 0 Spc7 kinetochore protein GAS PF13851.6 CBK22787.2 - 0.82 9.0 86.0 2.2 7.6 29.9 4.3 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding dCMP_cyt_deam_1 PF00383.23 CBK22788.2 - 7.7e-27 93.1 0.2 1.2e-26 92.5 0.2 1.3 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 CBK22788.2 - 1.2e-09 38.0 0.0 1.8e-09 37.4 0.0 1.3 1 0 0 1 1 1 1 MafB19-like deaminase PWWP PF00855.17 CBK22788.2 - 5.7e-07 29.9 0.0 1.4e-06 28.7 0.0 1.6 2 0 0 2 2 2 1 PWWP domain SNAD4 PF18750.1 CBK22788.2 - 0.025 14.7 0.2 0.047 13.8 0.2 1.4 1 0 0 1 1 1 0 Secreted Novel AID/APOBEC-like Deaminase 4 APOBEC3 PF18771.1 CBK22788.2 - 0.078 13.1 0.2 0.21 11.7 0.1 1.7 2 0 0 2 2 2 0 APOBEC3 APOBEC4_like PF18774.1 CBK22788.2 - 0.085 12.8 0.3 0.15 12.0 0.3 1.4 1 0 0 1 1 1 0 APOBEC4-like -AID/APOBEC-deaminase zf-4CXXC_R1 PF10497.9 CBK22789.2 - 0.00017 21.7 17.0 0.0003 20.9 17.0 1.5 1 0 0 1 1 1 1 Zinc-finger domain of monoamine-oxidase A repressor R1 Ank_3 PF13606.6 CBK22790.2 - 2.1e-07 30.7 0.1 8.3e-05 22.7 0.0 3.2 3 0 0 3 3 3 1 Ankyrin repeat Ank_2 PF12796.7 CBK22790.2 - 1.5e-06 28.7 0.0 0.012 16.1 0.0 2.2 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CBK22790.2 - 6.2e-06 26.6 0.0 0.029 15.0 0.0 3.3 2 1 0 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 CBK22790.2 - 1.1e-05 25.6 0.0 0.00072 19.8 0.0 2.4 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.30 CBK22790.2 - 6e-05 23.3 0.2 0.00081 19.7 0.0 2.5 3 0 0 3 3 3 1 Ankyrin repeat Hist_deacetyl PF00850.19 CBK22791.2 - 1.6e-44 152.6 0.0 4.2e-44 151.3 0.0 1.7 1 1 0 1 1 1 1 Histone deacetylase domain TerB_C PF15615.6 CBK22793.2 - 0.008 16.5 0.0 0.008 16.5 0.0 1.1 1 0 0 1 1 1 1 TerB-C domain EF1_GNE PF00736.19 CBK22794.2 - 0.072 13.3 0.0 0.14 12.3 0.0 1.5 1 0 0 1 1 1 0 EF-1 guanine nucleotide exchange domain LRR_4 PF12799.7 CBK22794.2 - 0.1 13.0 1.2 3 8.4 1.2 2.7 1 1 0 1 1 1 0 Leucine Rich repeats (2 copies) 6PF2K PF01591.18 CBK22795.2 - 6.3e-55 185.9 0.0 9.6e-55 185.3 0.0 1.3 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 CBK22795.2 - 0.042 13.5 0.0 0.088 12.5 0.0 1.5 2 0 0 2 2 2 0 Histidine phosphatase superfamily (branch 1) HNH_2 PF13391.6 CBK22795.2 - 0.11 12.6 0.0 0.28 11.4 0.0 1.7 1 0 0 1 1 1 0 HNH endonuclease ABC_tran PF00005.27 CBK22796.2 - 7.4e-45 152.8 0.0 3.4e-21 76.2 0.0 2.5 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 CBK22796.2 - 2.1e-14 54.1 5.0 0.003 17.4 0.1 4.3 3 1 0 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system ABC_tran_Xtn PF12848.7 CBK22796.2 - 3.1e-14 52.8 0.2 3.1e-14 52.8 0.2 3.0 4 0 0 4 4 3 1 ABC transporter SMC_N PF02463.19 CBK22796.2 - 2.9e-10 40.0 1.1 0.00015 21.3 0.2 3.6 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 CBK22796.2 - 2e-06 28.3 0.0 0.052 13.9 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 CBK22796.2 - 1.9e-05 24.6 0.5 0.2 11.5 0.0 2.8 3 0 0 3 3 3 2 RsgA GTPase AAA_15 PF13175.6 CBK22796.2 - 6e-05 22.9 2.8 1.8 8.2 0.0 3.7 3 1 0 4 4 4 2 AAA ATPase domain AAA_22 PF13401.6 CBK22796.2 - 6.4e-05 23.2 0.4 0.072 13.4 0.0 3.0 2 2 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 CBK22796.2 - 0.00016 22.0 0.0 0.17 12.3 0.0 2.8 2 0 0 2 2 2 1 RNA helicase AAA_29 PF13555.6 CBK22796.2 - 0.00017 21.3 1.3 0.5 10.1 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_24 PF13479.6 CBK22796.2 - 0.00019 21.2 0.0 0.64 9.7 0.0 2.8 2 0 0 2 2 2 2 AAA domain NB-ARC PF00931.22 CBK22796.2 - 0.00028 20.1 0.1 0.061 12.5 0.0 2.3 2 0 0 2 2 2 1 NB-ARC domain MMR_HSR1 PF01926.23 CBK22796.2 - 0.00031 20.8 0.0 0.63 10.1 0.0 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_5 PF07728.14 CBK22796.2 - 0.0009 19.2 0.1 2 8.4 0.0 3.5 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) NACHT PF05729.12 CBK22796.2 - 0.00099 19.1 0.1 0.19 11.6 0.0 2.4 2 0 0 2 2 2 1 NACHT domain AAA_28 PF13521.6 CBK22796.2 - 0.0013 19.0 0.0 0.3 11.3 0.0 2.7 2 1 0 2 2 2 1 AAA domain AAA PF00004.29 CBK22796.2 - 0.0014 19.1 0.0 0.94 9.9 0.0 3.4 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) DUF87 PF01935.17 CBK22796.2 - 0.0023 18.1 1.3 0.19 11.8 0.0 3.1 3 0 0 3 3 3 1 Helicase HerA, central domain AAA_14 PF13173.6 CBK22796.2 - 0.0037 17.3 0.6 5.7 7.0 0.1 3.4 3 1 0 3 3 3 2 AAA domain SbcCD_C PF13558.6 CBK22796.2 - 0.0055 16.9 0.2 0.66 10.2 0.0 3.4 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_25 PF13481.6 CBK22796.2 - 0.0064 16.1 0.0 0.14 11.7 0.0 2.9 4 0 0 4 4 4 1 AAA domain AAA_33 PF13671.6 CBK22796.2 - 0.012 15.8 3.4 1.1 9.4 0.0 3.3 3 1 0 3 3 3 0 AAA domain NTPase_1 PF03266.15 CBK22796.2 - 0.015 15.3 0.1 4.6 7.1 0.0 2.8 2 0 0 2 2 2 0 NTPase DUF720 PF05302.11 CBK22796.2 - 0.015 15.1 1.5 0.029 14.2 1.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF720) Roc PF08477.13 CBK22796.2 - 0.041 14.1 0.0 4.3 7.6 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_23 PF13476.6 CBK22796.2 - 0.1 13.1 13.0 0.38 11.2 0.1 4.0 5 0 0 5 5 5 0 AAA domain MeaB PF03308.16 CBK22796.2 - 0.13 11.3 0.1 5 6.0 0.0 2.3 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_18 PF13238.6 CBK22796.2 - 1.1 9.9 9.8 12 6.5 0.0 4.4 3 2 0 3 3 3 0 AAA domain Vps16_N PF04841.13 CBK22797.2 - 2.6e-31 108.8 0.0 3.3e-31 108.5 0.0 1.1 1 0 0 1 1 1 1 Vps16, N-terminal region Vps16_C PF04840.12 CBK22797.2 - 7.9e-08 31.7 0.0 1.3e-07 31.0 0.0 1.2 1 0 0 1 1 1 1 Vps16, C-terminal region CAP_GLY PF01302.25 CBK22797.2 - 0.16 12.0 0.0 1.5 8.9 0.0 2.1 2 0 0 2 2 2 0 CAP-Gly domain Vps16_C PF04840.12 CBK22798.2 - 1.2e-27 96.8 0.1 1.3e-27 96.8 0.1 1.0 1 0 0 1 1 1 1 Vps16, C-terminal region DAGK_acc PF00609.19 CBK22799.2 - 8.4e-38 130.2 0.0 1.3e-37 129.6 0.0 1.3 1 0 0 1 1 1 1 Diacylglycerol kinase accessory domain DAGK_cat PF00781.24 CBK22799.2 - 2.6e-20 72.3 0.0 5e-20 71.4 0.0 1.4 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain C1_1 PF00130.22 CBK22799.2 - 1.8e-08 34.1 5.4 3.6e-08 33.2 5.4 1.5 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-RING_9 PF13901.6 CBK22799.2 - 0.49 10.3 7.0 0.85 9.6 7.0 1.3 1 0 0 1 1 1 0 Putative zinc-RING and/or ribbon PfkB PF00294.24 CBK22800.2 - 0.014 14.8 0.0 0.02 14.2 0.0 1.4 1 1 0 1 1 1 0 pfkB family carbohydrate kinase Indigoidine_A PF04227.12 CBK22801.2 - 2.2e-12 46.9 0.0 2.8e-12 46.6 0.0 1.0 1 0 0 1 1 1 1 Indigoidine synthase A like protein IL34 PF15036.6 CBK22801.2 - 0.094 12.8 0.0 0.14 12.2 0.0 1.3 1 0 0 1 1 1 0 Interleukin 34 Succ_DH_flav_C PF02910.20 CBK22803.2 - 5.5e-28 97.5 0.1 6.3e-28 97.3 0.1 1.0 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term FAD_binding_2 PF00890.24 CBK22804.2 - 4.1e-121 405.0 3.1 5.4e-121 404.6 3.1 1.2 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.20 CBK22804.2 - 2.4e-44 150.4 1.8 3.5e-44 149.9 1.8 1.3 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term Thi4 PF01946.17 CBK22804.2 - 5.3e-06 25.8 0.2 0.0068 15.7 0.1 2.6 3 0 0 3 3 3 2 Thi4 family GIDA PF01134.22 CBK22804.2 - 5.6e-05 22.4 0.9 0.0031 16.7 1.0 2.2 2 0 0 2 2 2 1 Glucose inhibited division protein A Pyr_redox_2 PF07992.14 CBK22804.2 - 0.00011 21.6 0.3 0.0003 20.1 0.2 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 CBK22804.2 - 0.00023 20.5 0.2 0.00041 19.7 0.2 1.4 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 CBK22804.2 - 0.00024 20.8 0.5 0.00042 20.0 0.5 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_7 PF13241.6 CBK22804.2 - 0.019 15.4 0.0 0.81 10.2 0.0 2.5 2 0 0 2 2 2 0 Putative NAD(P)-binding HI0933_like PF03486.14 CBK22804.2 - 0.03 13.1 1.6 0.052 12.2 0.3 2.0 3 0 0 3 3 3 0 HI0933-like protein CAF1C_H4-bd PF12265.8 CBK22806.2 - 6.1e-18 64.8 0.3 3.3e-16 59.3 0.0 2.7 2 0 0 2 2 2 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex WD40 PF00400.32 CBK22806.2 - 5.1e-13 49.3 13.0 5.3e-06 27.1 0.3 4.9 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBK22806.2 - 0.00028 21.1 0.2 0.056 13.7 0.1 3.2 1 1 2 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain IKI3 PF04762.12 CBK22806.2 - 0.005 14.9 0.6 0.48 8.4 0.0 2.4 1 1 0 2 2 2 2 IKI3 family RRM_1 PF00076.22 CBK22807.2 - 7.9e-14 51.2 0.0 1.2e-13 50.7 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 CBK22807.2 - 0.013 15.5 0.0 0.024 14.7 0.0 1.3 1 0 0 1 1 1 0 RNA binding motif RNA_bind PF08675.11 CBK22807.2 - 0.02 14.9 0.0 0.037 14.1 0.0 1.4 1 0 0 1 1 1 0 RNA binding domain RRM_5 PF13893.6 CBK22807.2 - 0.026 14.1 0.0 0.034 13.7 0.0 1.2 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CDC45 PF02724.14 CBK22807.2 - 2.6 6.2 11.9 3.1 6.0 11.9 1.1 1 0 0 1 1 1 0 CDC45-like protein Presenilin PF01080.17 CBK22807.2 - 9.8 4.8 10.4 11 4.6 10.4 1.1 1 0 0 1 1 1 0 Presenilin DUF1765 PF08578.10 CBK22808.2 - 1.4e-11 44.9 8.5 3.7e-11 43.6 5.8 2.9 2 1 0 2 2 2 1 Protein of unknown function (DUF1765) DEP PF00610.21 CBK22808.2 - 0.1 12.7 0.3 1.1 9.4 0.0 2.4 2 0 0 2 2 2 0 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) AAA_5 PF07728.14 CBK22809.2 - 1.2e-55 187.3 0.0 1.6e-13 50.8 0.0 7.0 6 0 0 6 6 6 5 AAA domain (dynein-related subfamily) AAA_7 PF12775.7 CBK22809.2 - 2.8e-17 62.8 0.1 0.00048 19.7 0.0 6.1 6 0 0 6 6 6 4 P-loop containing dynein motor region AAA_3 PF07726.11 CBK22809.2 - 8.5e-12 45.1 0.0 1.9e-07 31.0 0.0 3.4 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 CBK22809.2 - 6.3e-11 42.4 1.6 0.0047 17.0 0.0 6.2 6 0 0 6 6 6 2 AAA domain Dynein_heavy PF03028.15 CBK22809.2 - 2.2e-10 40.7 0.0 5.8e-05 23.2 0.0 4.5 4 0 0 4 4 3 2 Dynein heavy chain region D6 P-loop domain AAA_22 PF13401.6 CBK22809.2 - 6.5e-09 36.2 7.9 0.27 11.5 0.1 8.0 7 2 0 7 7 6 2 AAA domain Sigma54_activat PF00158.26 CBK22809.2 - 3.9e-07 29.9 0.0 0.0047 16.7 0.0 4.5 5 0 0 5 5 5 2 Sigma-54 interaction domain AAA PF00004.29 CBK22809.2 - 5.4e-07 30.1 0.6 0.069 13.6 0.0 5.7 5 0 0 5 5 5 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 CBK22809.2 - 8e-06 26.3 0.0 4.2 7.7 0.0 5.6 5 0 0 5 5 5 1 AAA ATPase domain AAA_33 PF13671.6 CBK22809.2 - 0.00056 20.1 0.0 3.3 7.9 0.0 4.2 5 0 0 5 5 3 1 AAA domain CCB2_CCB4 PF11152.8 CBK22809.2 - 0.0084 15.4 0.1 0.087 12.1 0.0 2.5 3 0 0 3 3 3 1 Cofactor assembly of complex C subunit B, CCB2/CCB4 Viral_helicase1 PF01443.18 CBK22809.2 - 0.013 15.3 0.0 2.2 8.0 0.0 3.3 3 0 0 3 3 3 0 Viral (Superfamily 1) RNA helicase RNA_helicase PF00910.22 CBK22809.2 - 0.027 14.8 4.9 6.5 7.2 0.0 6.1 5 0 0 5 5 5 0 RNA helicase AAA_18 PF13238.6 CBK22809.2 - 0.034 14.7 3.3 47 4.5 0.0 5.5 6 0 0 6 6 5 0 AAA domain AAA_30 PF13604.6 CBK22809.2 - 0.039 13.7 0.0 6.5 6.4 0.0 4.0 4 0 0 4 4 4 0 AAA domain AAA_24 PF13479.6 CBK22809.2 - 0.24 11.1 6.3 22 4.7 0.0 5.1 6 0 0 6 6 6 0 AAA domain ABC_tran PF00005.27 CBK22809.2 - 1.8 9.1 7.7 14 6.2 0.0 4.6 4 0 0 4 4 4 0 ABC transporter E2F_CC-MB PF16421.5 CBK22809.2 - 2.4 8.6 6.7 35 4.9 1.1 3.4 2 0 0 2 2 2 0 E2F transcription factor CC-MB domain HRM PF02793.22 CBK22810.2 - 5.7e-17 61.8 88.6 0.00055 20.2 1.0 13.4 8 4 4 12 12 12 8 Hormone receptor domain fn3 PF00041.21 CBK22810.2 - 3.2e-10 40.2 0.2 0.00097 19.4 0.0 5.1 5 0 0 5 5 5 4 Fibronectin type III domain Big_5 PF13205.6 CBK22810.2 - 2.7e-05 24.8 10.1 4.1e-05 24.2 0.0 4.5 5 1 1 6 6 6 1 Bacterial Ig-like domain Torus PF16131.5 CBK22811.2 - 0.0012 19.6 4.8 0.0035 18.0 4.8 1.9 1 1 0 1 1 1 1 Torus domain zf_CCCH_4 PF18345.1 CBK22811.2 - 0.9 9.7 8.5 2.5 8.3 8.5 1.8 1 0 0 1 1 1 0 Zinc finger domain Zn_ribbon_2 PF12674.7 CBK22811.2 - 2.5 8.8 11.6 18 6.1 8.7 3.5 3 1 0 3 3 3 0 Putative zinc ribbon domain zf-CCCH_4 PF18044.1 CBK22811.2 - 4.3 7.3 10.4 1.1 9.1 6.7 2.0 2 0 0 2 2 2 0 CCCH-type zinc finger ABC_tran PF00005.27 CBK22812.2 - 8.6e-34 117.0 0.0 1.6e-15 57.9 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 CBK22812.2 - 1.9e-13 50.4 1.8 0.0011 18.4 0.0 4.1 3 1 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 CBK22812.2 - 2.3e-13 50.6 1.8 0.0041 17.0 0.0 4.2 2 2 1 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system RLI PF04068.15 CBK22812.2 - 1.3e-11 44.1 3.4 1.3e-11 44.1 3.4 1.9 2 0 0 2 2 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI Fer4 PF00037.27 CBK22812.2 - 4e-08 32.7 3.0 4e-08 32.7 3.0 2.2 2 0 0 2 2 1 1 4Fe-4S binding domain AAA_15 PF13175.6 CBK22812.2 - 1.6e-06 28.1 0.1 0.15 11.7 0.0 3.4 3 0 0 3 3 3 2 AAA ATPase domain AAA_16 PF13191.6 CBK22812.2 - 5.9e-06 26.8 0.0 0.083 13.3 0.0 2.6 2 1 0 2 2 2 2 AAA ATPase domain Fer4_6 PF12837.7 CBK22812.2 - 8.3e-06 25.7 2.0 8.3e-06 25.7 2.0 2.4 2 0 0 2 2 2 1 4Fe-4S binding domain AAA PF00004.29 CBK22812.2 - 5.7e-05 23.6 0.0 0.33 11.4 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 CBK22812.2 - 5.8e-05 23.1 0.1 0.022 14.7 0.1 3.2 2 1 1 3 3 3 1 Rad17 P-loop domain RsgA_GTPase PF03193.16 CBK22812.2 - 8e-05 22.6 0.1 0.42 10.5 0.0 2.9 2 0 0 2 2 2 2 RsgA GTPase NACHT PF05729.12 CBK22812.2 - 0.00011 22.2 0.5 0.051 13.5 0.0 2.6 3 0 0 3 3 2 1 NACHT domain SRP54 PF00448.22 CBK22812.2 - 0.00015 21.5 1.4 0.045 13.4 0.0 2.2 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_22 PF13401.6 CBK22812.2 - 0.00021 21.6 0.0 0.11 12.7 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 CBK22812.2 - 0.00027 20.6 0.2 0.64 9.8 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.6 CBK22812.2 - 0.00032 21.3 0.1 0.075 13.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain Fer4_7 PF12838.7 CBK22812.2 - 0.00034 21.2 1.1 0.00034 21.2 1.1 2.3 1 1 2 3 3 2 2 4Fe-4S dicluster domain Fer4_2 PF12797.7 CBK22812.2 - 0.00059 19.8 0.7 0.00059 19.8 0.7 2.4 2 0 0 2 2 2 1 4Fe-4S binding domain AAA_24 PF13479.6 CBK22812.2 - 0.0012 18.6 0.7 0.41 10.3 0.0 2.6 2 1 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 CBK22812.2 - 0.0018 18.6 0.0 3.2 8.2 0.0 2.8 2 0 0 2 2 2 1 RNA helicase AAA_30 PF13604.6 CBK22812.2 - 0.0019 18.0 0.1 0.38 10.4 0.0 2.6 2 0 0 2 2 2 1 AAA domain Fer4_10 PF13237.6 CBK22812.2 - 0.0027 17.8 1.4 0.0027 17.8 1.4 2.4 1 1 1 2 2 2 2 4Fe-4S dicluster domain AAA_33 PF13671.6 CBK22812.2 - 0.0028 17.8 0.0 1.6 8.9 0.0 2.6 2 0 0 2 2 2 1 AAA domain TsaE PF02367.17 CBK22812.2 - 0.0031 17.5 0.0 0.13 12.3 0.0 2.4 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE SbcCD_C PF13558.6 CBK22812.2 - 0.004 17.4 0.0 0.52 10.6 0.0 2.9 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit Fer4_16 PF13484.6 CBK22812.2 - 0.0049 17.8 0.3 0.0049 17.8 0.3 2.3 2 0 0 2 2 1 1 4Fe-4S double cluster binding domain Fer4_9 PF13187.6 CBK22812.2 - 0.005 17.0 10.7 0.0094 16.1 10.7 1.5 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_21 PF14697.6 CBK22812.2 - 0.0083 16.2 11.1 0.022 14.9 11.1 1.7 1 1 0 1 1 1 1 4Fe-4S dicluster domain Thymidylate_kin PF02223.17 CBK22812.2 - 0.013 15.2 0.1 2.1 8.0 0.0 2.5 2 0 0 2 2 2 0 Thymidylate kinase AAA_5 PF07728.14 CBK22812.2 - 0.015 15.3 0.6 1.2 9.1 0.0 2.9 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) AAA_28 PF13521.6 CBK22812.2 - 0.021 15.1 1.7 2.4 8.4 0.0 2.8 3 0 0 3 3 2 0 AAA domain DUF815 PF05673.13 CBK22812.2 - 0.028 13.6 0.1 2.3 7.3 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_18 PF13238.6 CBK22812.2 - 0.032 14.8 0.0 7.7 7.1 0.0 2.5 2 0 0 2 2 2 0 AAA domain VirE PF05272.11 CBK22812.2 - 0.041 13.6 0.0 5.4 6.7 0.0 2.3 2 0 0 2 2 2 0 Virulence-associated protein E AAA_7 PF12775.7 CBK22812.2 - 0.047 13.2 0.1 1.2 8.6 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_13 PF13166.6 CBK22812.2 - 0.11 11.1 0.5 0.22 10.1 0.0 1.7 2 0 0 2 2 1 0 AAA domain AAA_14 PF13173.6 CBK22812.2 - 0.12 12.4 0.0 12 5.9 0.0 2.9 3 0 0 3 3 2 0 AAA domain AAA_19 PF13245.6 CBK22812.2 - 0.12 12.7 0.3 1.5 9.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 CBK22812.2 - 0.13 12.3 1.3 14 5.8 0.0 2.9 3 0 0 3 3 2 0 50S ribosome-binding GTPase Fer4_8 PF13183.6 CBK22812.2 - 0.14 12.7 0.2 0.14 12.7 0.2 2.2 2 0 0 2 2 1 0 4Fe-4S dicluster domain DUF359 PF04019.12 CBK22812.2 - 0.14 11.8 0.1 0.44 10.2 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF359) KAP_NTPase PF07693.14 CBK22812.2 - 0.14 11.4 0.0 4.2 6.5 0.0 2.2 2 0 0 2 2 2 0 KAP family P-loop domain NB-ARC PF00931.22 CBK22812.2 - 0.15 11.3 0.0 9.6 5.3 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain NTPase_1 PF03266.15 CBK22812.2 - 1.1 9.1 4.9 8.1 6.3 0.0 3.2 4 0 0 4 4 3 0 NTPase Fer4_4 PF12800.7 CBK22812.2 - 3.8 8.3 15.1 0.14 12.7 3.2 2.5 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_3 PF12798.7 CBK22812.2 - 7.4 7.8 14.2 0.085 13.8 4.2 2.5 2 1 0 2 2 1 0 4Fe-4S binding domain tRNA-synt_1b PF00579.25 CBK22814.2 - 1.6e-73 247.6 0.0 2.1e-73 247.2 0.0 1.0 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) Phospholip_A2_1 PF00068.19 CBK22814.2 - 0.012 16.1 0.1 1.3 9.5 0.2 2.3 2 0 0 2 2 2 0 Phospholipase A2 GATase_5 PF13507.6 CBK22815.2 - 4.1e-107 357.1 0.0 5.6e-107 356.7 0.0 1.2 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain AIRS_C PF02769.22 CBK22815.2 - 1.1e-34 119.8 3.0 5.6e-20 72.0 0.8 2.3 2 0 0 2 2 2 2 AIR synthase related protein, C-terminal domain FGAR-AT_N PF18076.1 CBK22815.2 - 7.7e-19 67.8 0.0 1.5e-18 66.8 0.0 1.4 1 0 0 1 1 1 1 Formylglycinamide ribonucleotide amidotransferase N-terminal FGAR-AT_linker PF18072.1 CBK22815.2 - 6e-10 39.5 0.0 1.5e-09 38.3 0.0 1.7 1 0 0 1 1 1 1 Formylglycinamide ribonucleotide amidotransferase linker domain AIRS PF00586.24 CBK22815.2 - 0.0023 18.6 0.6 0.22 12.2 0.0 2.7 2 0 0 2 2 2 1 AIR synthase related protein, N-terminal domain GDP_Man_Dehyd PF16363.5 CBK22816.2 - 6.2e-77 259.2 0.4 7.8e-77 258.9 0.4 1.1 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 CBK22816.2 - 4.8e-62 209.6 0.4 7.4e-62 209.0 0.4 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 CBK22816.2 - 3.4e-25 88.6 0.3 4.6e-25 88.2 0.3 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 CBK22816.2 - 6.1e-23 81.4 0.1 6e-22 78.1 0.1 2.0 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 CBK22816.2 - 3.5e-19 69.0 0.0 4.9e-19 68.5 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 CBK22816.2 - 2e-18 66.5 0.2 2.4e-15 56.4 0.1 2.2 2 0 0 2 2 2 2 Male sterility protein Histone PF00125.24 CBK22816.2 - 2.9e-16 60.0 0.0 4.5e-16 59.4 0.0 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Histone_H2A_C PF16211.5 CBK22816.2 - 1.2e-08 34.6 0.1 2.2e-08 33.7 0.1 1.4 1 0 0 1 1 1 1 C-terminus of histone H2A NAD_binding_10 PF13460.6 CBK22816.2 - 1.2e-07 31.8 0.0 3.1e-07 30.5 0.0 1.7 1 0 0 1 1 1 1 NAD(P)H-binding CBFD_NFYB_HMF PF00808.23 CBK22816.2 - 0.011 16.0 0.0 0.021 15.1 0.0 1.5 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone DUF4110 PF13422.6 CBK22817.2 - 0.075 13.1 3.2 0.095 12.8 3.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4110) PHD PF00628.29 CBK22818.2 - 3.8e-10 39.5 39.4 8.6e-05 22.4 4.8 3.3 3 0 0 3 3 3 3 PHD-finger He_PIG PF05345.12 CBK22819.2 - 1.4e-27 95.6 46.3 9e-07 29.0 1.2 7.6 8 0 0 8 8 8 6 Putative Ig domain F5_F8_type_C PF00754.25 CBK22819.2 - 2.9e-07 30.6 18.0 0.0086 16.2 0.4 4.2 3 0 0 3 3 3 3 F5/8 type C domain DUF11 PF01345.18 CBK22819.2 - 0.00052 20.3 0.0 2.4 8.5 0.0 4.8 2 2 0 2 2 2 1 Domain of unknown function DUF11 I-set PF07679.16 CBK22819.2 - 0.0032 17.5 5.4 7.2 6.8 0.1 4.5 4 0 0 4 4 4 2 Immunoglobulin I-set domain DUF3185 PF11381.8 CBK22819.2 - 0.07 13.2 3.0 0.24 11.4 3.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3185) HRM PF02793.22 CBK22819.2 - 0.26 11.6 15.0 2.7 8.3 0.1 5.2 5 0 0 5 5 5 0 Hormone receptor domain Colicin_D PF11429.8 CBK22819.2 - 0.49 10.9 4.3 0.31 11.5 0.9 2.5 2 0 0 2 2 2 0 Colicin D MatE PF01554.18 CBK22820.2 - 2e-32 112.1 22.9 1e-18 67.5 3.6 2.7 2 1 0 2 2 2 2 MatE UPF0242 PF06785.11 CBK22820.2 - 0.86 9.7 3.2 37 4.3 2.3 2.4 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus IF4E PF01652.18 CBK22821.2 - 2e-30 105.7 0.8 3e-30 105.1 0.8 1.2 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E PCNA_N PF00705.18 CBK22822.2 - 6.3e-48 161.7 3.1 1e-47 161.0 3.1 1.3 1 0 0 1 1 1 1 Proliferating cell nuclear antigen, N-terminal domain PCNA_C PF02747.15 CBK22822.2 - 1.3e-43 148.2 0.0 3e-43 147.1 0.0 1.6 2 0 0 2 2 2 1 Proliferating cell nuclear antigen, C-terminal domain Rad1 PF02144.16 CBK22822.2 - 2.2e-06 26.9 0.8 3.1e-05 23.2 0.8 2.0 1 1 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 Rad9 PF04139.13 CBK22822.2 - 0.00017 21.1 0.2 0.0002 20.9 0.2 1.1 1 0 0 1 1 1 1 Rad9 Hus1 PF04005.12 CBK22822.2 - 0.015 14.4 0.0 3.8 6.5 0.0 2.3 1 1 1 2 2 2 0 Hus1-like protein Collagen PF01391.18 CBK22823.2 - 4e-60 199.4 236.8 5.7e-09 35.6 34.2 8.1 2 2 7 9 9 9 9 Collagen triple helix repeat (20 copies) zf-C2H2 PF00096.26 CBK22824.2 - 3e-20 71.5 27.4 4.3e-06 26.9 0.3 4.3 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CBK22824.2 - 3.7e-16 58.4 25.1 0.0006 20.4 0.3 4.4 4 0 0 4 4 4 4 C2H2-type zinc finger zf-H2C2_2 PF13465.6 CBK22824.2 - 4.8e-15 55.2 31.8 2e-07 31.1 1.3 5.2 5 0 0 5 5 5 3 Zinc-finger double domain zf-C2H2_aberr PF17017.5 CBK22824.2 - 3.9e-08 33.6 13.7 0.059 13.5 0.0 3.9 2 1 1 4 4 4 3 Aberrant zinc-finger zf-C2H2_8 PF15909.5 CBK22824.2 - 1.1e-07 32.0 10.6 0.0012 19.1 7.9 2.3 1 1 1 2 2 2 2 C2H2-type zinc ribbon zf-C2H2_11 PF16622.5 CBK22824.2 - 7e-05 22.5 13.7 0.0036 17.0 0.9 3.5 3 0 0 3 3 3 2 zinc-finger C2H2-type FOXP-CC PF16159.5 CBK22824.2 - 0.00081 20.0 17.1 0.92 10.2 1.3 4.2 1 1 3 4 4 4 3 FOXP coiled-coil domain zf-C2H2_6 PF13912.6 CBK22824.2 - 0.0096 15.9 20.9 0.85 9.7 0.3 4.7 4 0 0 4 4 4 3 C2H2-type zinc finger Furin-like_2 PF15913.5 CBK22824.2 - 0.06 13.5 1.4 0.06 13.5 1.4 3.0 1 1 2 3 3 3 0 Furin-like repeat, cysteine-rich zf-C2H2_jaz PF12171.8 CBK22824.2 - 0.29 11.5 0.1 0.29 11.5 0.1 4.2 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 CBK22824.2 - 0.54 10.7 0.0 0.54 10.7 0.0 4.1 4 0 0 4 4 4 0 Zinc-finger of C2H2 type G_path_suppress PF15991.5 CBK22825.2 - 0.023 14.9 2.7 0.031 14.4 2.7 1.1 1 0 0 1 1 1 0 G-protein pathway suppressor RNA_pol_3_Rpc31 PF11705.8 CBK22825.2 - 4.3 7.5 12.9 6.7 6.9 12.9 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Isy1 PF06246.12 CBK22826.2 - 1.8e-58 198.1 3.0 2e-58 198.0 3.0 1.0 1 0 0 1 1 1 1 Isy1-like splicing family PCNA_N PF00705.18 CBK22827.2 - 6.3e-48 161.7 3.1 1e-47 161.0 3.1 1.3 1 0 0 1 1 1 1 Proliferating cell nuclear antigen, N-terminal domain PCNA_C PF02747.15 CBK22827.2 - 1.3e-43 148.2 0.0 3e-43 147.1 0.0 1.6 2 0 0 2 2 2 1 Proliferating cell nuclear antigen, C-terminal domain Rad1 PF02144.16 CBK22827.2 - 2.2e-06 26.9 0.8 3.1e-05 23.2 0.8 2.0 1 1 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 Rad9 PF04139.13 CBK22827.2 - 0.00017 21.1 0.2 0.0002 20.9 0.2 1.1 1 0 0 1 1 1 1 Rad9 Hus1 PF04005.12 CBK22827.2 - 0.015 14.4 0.0 3.8 6.5 0.0 2.3 1 1 1 2 2 2 0 Hus1-like protein IF4E PF01652.18 CBK22828.2 - 2e-30 105.7 0.8 3e-30 105.1 0.8 1.2 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E PCNA_N PF00705.18 CBK22829.2 - 6.3e-48 161.7 3.1 1e-47 161.0 3.1 1.3 1 0 0 1 1 1 1 Proliferating cell nuclear antigen, N-terminal domain PCNA_C PF02747.15 CBK22829.2 - 1.3e-43 148.2 0.0 3e-43 147.1 0.0 1.6 2 0 0 2 2 2 1 Proliferating cell nuclear antigen, C-terminal domain Rad1 PF02144.16 CBK22829.2 - 2.2e-06 26.9 0.8 3.1e-05 23.2 0.8 2.0 1 1 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 Rad9 PF04139.13 CBK22829.2 - 0.00017 21.1 0.2 0.0002 20.9 0.2 1.1 1 0 0 1 1 1 1 Rad9 Hus1 PF04005.12 CBK22829.2 - 0.015 14.4 0.0 3.8 6.5 0.0 2.3 1 1 1 2 2 2 0 Hus1-like protein ESSS PF10183.9 CBK22831.2 - 0.015 15.5 0.0 0.016 15.4 0.0 1.2 1 0 0 1 1 1 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) DUF2298 PF10060.9 CBK22831.2 - 0.086 11.5 0.0 0.086 11.5 0.0 1.0 1 0 0 1 1 1 0 Uncharacterized membrane protein (DUF2298) Cyclin PF08613.11 CBK22832.2 - 1.5e-09 38.5 1.0 2e-09 38.0 1.0 1.2 1 0 0 1 1 1 1 Cyclin RNA_pol_Rpc82 PF05645.13 CBK22834.2 - 0.0002 21.2 0.4 0.00079 19.3 0.1 2.0 2 1 0 3 3 3 1 RNA polymerase III subunit RPC82 TFIIE_alpha PF02002.17 CBK22834.2 - 0.0091 15.9 1.4 0.039 13.8 0.1 2.6 3 0 0 3 3 3 1 TFIIE alpha subunit BLOC1_2 PF10046.9 CBK22835.2 - 1.3e-05 25.3 0.3 1.8e-05 25.0 0.3 1.3 1 1 0 1 1 1 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 iPGM_N PF06415.13 CBK22836.2 - 2.9e-10 40.0 0.0 4e-10 39.5 0.0 1.2 1 0 0 1 1 1 1 BPG-independent PGAM N-terminus (iPGM_N) Metalloenzyme PF01676.18 CBK22836.2 - 0.00012 21.6 0.0 0.00012 21.6 0.0 1.2 1 0 0 1 1 1 1 Metalloenzyme superfamily iPGM_N PF06415.13 CBK22837.2 - 4.6e-05 23.0 0.0 8.7e-05 22.1 0.0 1.5 1 0 0 1 1 1 1 BPG-independent PGAM N-terminus (iPGM_N) Metalloenzyme PF01676.18 CBK22837.2 - 0.0075 15.7 0.0 0.0099 15.3 0.0 1.2 1 0 0 1 1 1 1 Metalloenzyme superfamily Macro PF01661.21 CBK22838.2 - 9.1e-07 28.9 0.0 1.9e-06 27.9 0.0 1.5 1 0 0 1 1 1 1 Macro domain RRM_1 PF00076.22 CBK22839.2 - 9.4e-15 54.2 0.0 1.8e-14 53.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ribosomal_L2_C PF03947.18 CBK22840.2 - 1.4e-45 154.6 1.6 2.1e-45 154.0 1.6 1.2 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 CBK22840.2 - 1.2e-14 54.0 0.1 3.4e-14 52.6 0.0 1.9 2 0 0 2 2 2 1 Ribosomal Proteins L2, RNA binding domain Spc7 PF08317.11 CBK22841.2 - 0.0081 15.1 18.5 0.0093 14.9 18.5 1.0 1 0 0 1 1 1 1 Spc7 kinetochore protein DUF3037 PF11236.8 CBK22841.2 - 0.025 15.0 4.9 0.7 10.3 0.2 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3037) DUF1409 PF07197.12 CBK22841.2 - 0.047 13.6 0.9 0.14 12.1 0.1 2.2 2 1 1 3 3 3 0 Protein of unknown function (DUF1409) OmpH PF03938.14 CBK22841.2 - 0.084 13.2 18.0 0.14 12.5 18.0 1.4 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) UPF0242 PF06785.11 CBK22841.2 - 0.16 12.1 15.8 0.24 11.5 15.8 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Ly49 PF08391.10 CBK22841.2 - 0.23 11.8 15.8 1.5 9.2 4.2 2.1 1 1 1 2 2 2 0 Ly49-like protein, N-terminal region DUF724 PF05266.14 CBK22841.2 - 1.4 8.7 21.4 0.31 10.9 11.6 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF724) TPR_MLP1_2 PF07926.12 CBK22841.2 - 1.6 8.8 22.9 6.7 6.8 22.9 1.8 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein DUF4407 PF14362.6 CBK22841.2 - 1.6 8.0 11.8 0.67 9.3 5.5 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) DUF4200 PF13863.6 CBK22841.2 - 2 8.8 27.6 4.9 7.6 27.6 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4200) V_ATPase_I PF01496.19 CBK22841.2 - 3.6 5.4 14.7 4 5.2 14.7 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family zf-C4H2 PF10146.9 CBK22841.2 - 4 7.7 19.7 5.3 7.3 19.7 1.3 1 0 0 1 1 1 0 Zinc finger-containing protein HalX PF08663.10 CBK22841.2 - 5.6 7.4 13.9 0.33 11.3 7.7 2.2 2 1 1 3 3 3 0 HalX domain DUF1664 PF07889.12 CBK22841.2 - 8.1 6.5 13.6 5.8 7.0 1.5 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF1664) TMPIT PF07851.13 CBK22841.2 - 9.3 5.4 15.4 30 3.7 15.4 1.7 1 1 0 1 1 1 0 TMPIT-like protein AAA_12 PF13087.6 CBK22842.2 - 6.3e-51 172.8 0.2 1.8e-50 171.3 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.6 CBK22842.2 - 2.3e-37 129.2 5.1 3e-19 69.8 1.0 2.8 1 1 2 3 3 3 2 AAA domain AAA_19 PF13245.6 CBK22842.2 - 3.3e-11 43.7 0.0 1.7e-10 41.4 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 CBK22842.2 - 2.3e-10 40.5 0.1 3.2e-07 30.2 0.0 2.7 3 0 0 3 3 3 2 AAA domain Viral_helicase1 PF01443.18 CBK22842.2 - 1.2e-09 38.3 0.0 0.034 13.9 0.0 3.3 3 0 0 3 3 3 3 Viral (Superfamily 1) RNA helicase UvrD_C_2 PF13538.6 CBK22842.2 - 3.4e-06 26.8 0.1 0.012 15.5 0.0 2.8 2 1 0 2 2 2 2 UvrD-like helicase C-terminal domain Helicase_RecD PF05127.14 CBK22842.2 - 4.5e-05 23.4 0.0 0.00084 19.2 0.0 2.6 2 1 0 2 2 2 1 Helicase ResIII PF04851.15 CBK22842.2 - 7.2e-05 22.9 0.0 0.00017 21.6 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_16 PF13191.6 CBK22842.2 - 0.00036 21.0 0.6 0.037 14.4 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain AAA PF00004.29 CBK22842.2 - 0.00048 20.6 0.2 0.013 15.9 0.9 3.0 2 1 1 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 CBK22842.2 - 0.00066 20.0 2.5 0.077 13.3 0.1 4.1 4 2 0 4 4 4 1 AAA domain DUF2075 PF09848.9 CBK22842.2 - 0.0012 18.2 0.2 0.03 13.6 0.1 2.9 2 1 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) UvrD-helicase PF00580.21 CBK22842.2 - 0.0021 17.7 0.0 0.05 13.1 0.0 2.2 1 1 0 2 2 2 1 UvrD/REP helicase N-terminal domain T2SSE PF00437.20 CBK22842.2 - 0.0063 15.6 0.3 0.015 14.4 0.1 1.7 2 0 0 2 2 2 1 Type II/IV secretion system protein DEAD PF00270.29 CBK22842.2 - 0.033 14.0 0.9 0.38 10.5 0.1 2.6 2 1 0 3 3 3 0 DEAD/DEAH box helicase AAA_18 PF13238.6 CBK22842.2 - 0.79 10.3 3.0 2.4 8.7 0.0 3.0 4 0 0 4 4 4 0 AAA domain DUF4147 PF13660.6 CBK22843.2 - 1.1e-76 257.4 0.0 1.6e-76 256.9 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4147) MOFRL PF05161.13 CBK22843.2 - 5.9e-35 119.8 3.0 1.3e-34 118.6 3.0 1.7 1 0 0 1 1 1 1 MOFRL family AIRS_C PF02769.22 CBK22846.2 - 3.7e-25 88.9 0.2 5.1e-25 88.4 0.2 1.2 1 0 0 1 1 1 1 AIR synthase related protein, C-terminal domain AIRS PF00586.24 CBK22846.2 - 0.02 15.5 0.5 0.057 14.1 0.1 1.9 2 0 0 2 2 2 0 AIR synthase related protein, N-terminal domain Peptidase_S24 PF00717.23 CBK22846.2 - 0.11 12.5 0.0 27 4.8 0.0 2.8 3 0 0 3 3 3 0 Peptidase S24-like CAF1C_H4-bd PF12265.8 CBK22847.2 - 4.8e-07 29.9 1.9 1.6e-06 28.2 1.7 2.1 2 1 0 2 2 2 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex MIF4G PF02854.19 CBK22849.2 - 8.5e-06 25.6 3.8 1.8e-05 24.5 3.8 1.6 1 0 0 1 1 1 1 MIF4G domain DUF3420 PF11900.8 CBK22849.2 - 0.071 13.3 0.0 0.21 11.8 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF3420) XPG_I_2 PF12813.7 CBK22850.2 - 1.3e-06 28.1 0.4 2.9e-06 26.9 0.3 1.6 1 1 0 1 1 1 1 XPG domain containing DUF5615 PF18480.1 CBK22850.2 - 0.00034 20.3 0.0 0.001 18.7 0.0 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF5615) NUC130_3NT PF08158.12 CBK22850.2 - 0.015 15.6 0.1 0.07 13.5 0.1 2.1 2 0 0 2 2 2 0 NUC130/3NT domain Tau95 PF09734.9 CBK22851.2 - 1.8e-22 80.6 0.3 3.3e-22 79.8 0.3 1.4 1 0 0 1 1 1 1 RNA polymerase III transcription factor (TF)IIIC subunit HTH domain Adap_comp_sub PF00928.21 CBK22852.2 - 2.8e-58 197.4 0.1 3.9e-58 196.9 0.1 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 CBK22852.2 - 5e-06 26.5 0.0 9.4e-06 25.6 0.0 1.5 1 0 0 1 1 1 1 Clathrin adaptor complex small chain BRK PF07533.16 CBK22852.2 - 0.12 12.0 0.0 0.4 10.3 0.0 1.9 2 0 0 2 2 2 0 BRK domain NAD_Gly3P_dh_C PF07479.14 CBK22853.2 - 3.5e-47 160.3 0.1 5.3e-47 159.7 0.1 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus NAD_Gly3P_dh_N PF01210.23 CBK22853.2 - 6.1e-36 123.8 0.0 1.1e-35 122.9 0.0 1.4 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus F420_oxidored PF03807.17 CBK22853.2 - 0.0008 20.0 0.0 0.38 11.4 0.0 2.5 2 0 0 2 2 2 2 NADP oxidoreductase coenzyme F420-dependent Pkinase PF00069.25 CBK22854.2 - 1.4e-72 244.2 0.0 2.1e-72 243.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBK22854.2 - 1.4e-54 185.1 0.0 2.5e-54 184.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CBK22854.2 - 5e-06 25.6 0.0 8.7e-06 24.8 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 CBK22854.2 - 0.00055 19.3 0.0 0.0013 18.1 0.0 1.6 1 1 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 CBK22854.2 - 0.018 14.0 0.1 3.7 6.4 0.0 2.3 1 1 1 2 2 2 0 Haspin like kinase domain WHEP-TRS PF00458.20 CBK22854.2 - 0.058 13.6 0.1 0.12 12.6 0.1 1.4 1 0 0 1 1 1 0 WHEP-TRS domain Lactamase_B_3 PF13483.6 CBK22855.2 - 6.1e-25 88.0 0.3 8.1e-25 87.6 0.3 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_2 PF12706.7 CBK22855.2 - 1e-18 67.6 1.2 1.3e-18 67.3 1.2 1.1 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 CBK22855.2 - 1.1e-11 45.2 2.0 2.4e-11 44.0 1.9 1.7 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Kinase-like PF14531.6 CBK22855.2 - 0.22 10.8 0.0 0.32 10.3 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Alpha-amylase_C PF02806.18 CBK22856.2 - 0.0027 18.1 0.0 0.014 15.9 0.0 2.1 2 0 0 2 2 2 1 Alpha amylase, C-terminal all-beta domain Malt_amylase_C PF16657.5 CBK22856.2 - 0.11 12.7 0.0 11 6.3 0.0 3.2 3 0 0 3 3 3 0 Maltogenic Amylase, C-terminal domain SurA_N_3 PF13624.6 CBK22856.2 - 0.15 11.8 0.0 0.33 10.7 0.0 1.5 1 0 0 1 1 1 0 SurA N-terminal domain Ins_P5_2-kin PF06090.12 CBK22859.2 - 1.4e-20 74.0 0.0 1.6e-20 73.8 0.0 1.0 1 0 0 1 1 1 1 Inositol-pentakisphosphate 2-kinase DUF4379 PF14311.6 CBK22860.2 - 4.1e-31 107.1 17.2 2e-17 63.3 2.4 3.0 3 0 0 3 3 3 2 Probable Zinc-ribbon domain Prok-RING_4 PF14447.6 CBK22860.2 - 0.0018 18.1 2.6 1.8 8.5 0.2 3.3 3 0 0 3 3 3 2 Prokaryotic RING finger family 4 zf-Di19 PF05605.12 CBK22860.2 - 0.017 15.4 6.8 0.34 11.2 0.6 3.1 3 0 0 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding zf-C2HC5 PF06221.13 CBK22860.2 - 0.042 13.8 4.3 5.2 7.1 0.3 3.0 3 0 0 3 3 3 0 Putative zinc finger motif, C2HC5-type zf-LITAF-like PF10601.9 CBK22860.2 - 0.081 13.2 3.7 22 5.4 0.1 3.3 3 0 0 3 3 3 0 LITAF-like zinc ribbon domain zf-H2C2_2 PF13465.6 CBK22860.2 - 0.44 11.1 5.2 63 4.3 0.2 3.6 3 0 0 3 3 3 0 Zinc-finger double domain zf-C3HC4_3 PF13920.6 CBK22860.2 - 0.44 10.4 9.4 19 5.2 0.2 3.7 3 1 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.8 CBK22860.2 - 0.46 10.7 4.6 4.5 7.5 0.1 3.1 3 0 0 3 3 3 0 FANCL C-terminal domain UBZ_FAAP20 PF15750.5 CBK22860.2 - 1.9 8.5 4.1 12 6.0 0.1 2.7 3 0 0 3 3 3 0 Ubiquitin-binding zinc-finger Cyclin_N PF00134.23 CBK22861.2 - 4.3e-15 55.6 2.0 4.7e-15 55.4 2.0 1.1 1 0 0 1 1 1 1 Cyclin, N-terminal domain Pkinase PF00069.25 CBK22862.2 - 8.5e-09 35.2 0.0 1.1e-08 34.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Dus PF01207.17 CBK22863.2 - 1.5e-43 149.1 0.0 2e-43 148.7 0.0 1.1 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) zf-CCCH_4 PF18044.1 CBK22863.2 - 5.9e-07 29.1 8.4 9.6e-05 22.1 0.6 3.1 3 0 0 3 3 3 2 CCCH-type zinc finger Torus PF16131.5 CBK22863.2 - 0.00041 21.0 1.4 0.0097 16.6 0.3 2.4 2 0 0 2 2 2 1 Torus domain zf-CCCH PF00642.24 CBK22863.2 - 0.018 15.0 8.4 0.036 14.0 0.8 3.2 3 0 0 3 3 3 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) AAA PF00004.29 CBK22866.2 - 9.2e-38 129.7 0.0 3.5e-37 127.8 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CBK22866.2 - 2e-14 53.1 0.7 7.3e-14 51.3 0.7 2.1 1 1 0 1 1 1 1 AAA+ lid domain Vps4_C PF09336.10 CBK22866.2 - 4.5e-09 36.2 0.0 8.4e-09 35.3 0.0 1.4 1 0 0 1 1 1 1 Vps4 C terminal oligomerisation domain RuvB_N PF05496.12 CBK22866.2 - 2.3e-05 24.2 0.0 4.1e-05 23.4 0.0 1.4 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 CBK22866.2 - 0.0002 21.4 0.1 0.0024 17.9 0.1 2.4 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 CBK22866.2 - 0.00024 21.4 0.1 0.0022 18.3 0.1 2.2 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.6 CBK22866.2 - 0.00039 20.8 0.3 0.0012 19.2 0.0 2.0 1 1 1 2 2 2 1 AAA ATPase domain IstB_IS21 PF01695.17 CBK22866.2 - 0.00067 19.4 0.0 0.0011 18.7 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein TIP49 PF06068.13 CBK22866.2 - 0.00075 18.8 0.0 0.0012 18.2 0.0 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain MHCassoc_trimer PF08831.10 CBK22866.2 - 0.00091 19.2 0.1 0.0036 17.3 0.0 1.9 2 0 0 2 2 2 1 Class II MHC-associated invariant chain trimerisation domain ATPase PF06745.13 CBK22866.2 - 0.0018 17.6 0.1 0.49 9.7 0.1 2.9 2 1 1 3 3 3 1 KaiC AAA_33 PF13671.6 CBK22866.2 - 0.0026 17.9 0.1 0.0068 16.6 0.1 1.9 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 CBK22866.2 - 0.0038 17.8 0.4 0.015 15.9 0.0 2.2 3 0 0 3 3 3 1 AAA domain AAA_2 PF07724.14 CBK22866.2 - 0.004 17.3 0.0 0.0088 16.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) Mg_chelatase PF01078.21 CBK22866.2 - 0.0053 16.2 0.0 0.0094 15.4 0.0 1.3 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI TsaE PF02367.17 CBK22866.2 - 0.007 16.4 0.0 0.012 15.7 0.0 1.3 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_14 PF13173.6 CBK22866.2 - 0.0077 16.3 0.0 0.016 15.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain Parvo_NS1 PF01057.17 CBK22866.2 - 0.0096 15.0 0.0 0.014 14.5 0.0 1.2 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 AAA_24 PF13479.6 CBK22866.2 - 0.012 15.3 0.0 0.023 14.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 CBK22866.2 - 0.017 15.5 0.0 0.032 14.6 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_7 PF12775.7 CBK22866.2 - 0.017 14.6 0.0 0.04 13.4 0.0 1.6 1 1 0 1 1 1 0 P-loop containing dynein motor region AAA_28 PF13521.6 CBK22866.2 - 0.032 14.5 0.1 0.082 13.1 0.0 1.8 2 0 0 2 2 1 0 AAA domain PhoH PF02562.16 CBK22866.2 - 0.056 12.9 0.0 0.1 12.1 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein AAA_25 PF13481.6 CBK22866.2 - 0.061 12.9 0.2 0.19 11.3 0.1 1.8 1 1 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 CBK22866.2 - 0.076 12.7 0.0 0.26 11.0 0.0 1.9 3 0 0 3 3 3 0 Sigma-54 interaction domain ABC_tran PF00005.27 CBK22866.2 - 0.078 13.5 0.0 0.12 12.8 0.0 1.8 1 1 0 1 1 1 0 ABC transporter SRPRB PF09439.10 CBK22866.2 - 0.13 11.7 0.0 0.23 10.9 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit NACHT PF05729.12 CBK22866.2 - 0.14 12.1 0.0 0.26 11.2 0.0 1.5 1 0 0 1 1 1 0 NACHT domain DUF2075 PF09848.9 CBK22866.2 - 0.16 11.2 0.1 0.34 10.1 0.0 1.5 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) PHO4 PF01384.20 CBK22867.2 - 3.3e-116 388.0 15.4 4.3e-116 387.6 15.4 1.1 1 0 0 1 1 1 1 Phosphate transporter family Neur_chan_memb PF02932.16 CBK22867.2 - 0.023 14.8 0.1 0.023 14.8 0.1 1.7 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region LapA_dom PF06305.11 CBK22867.2 - 0.074 12.9 0.1 0.074 12.9 0.1 4.0 5 0 0 5 5 5 0 Lipopolysaccharide assembly protein A domain Na_H_antiporter PF03553.14 CBK22868.2 - 5.9e-49 166.9 14.9 5.9e-49 166.9 14.9 2.4 1 1 1 2 2 2 1 Na+/H+ antiporter family HemX PF04375.14 CBK22868.2 - 0.055 12.8 0.1 0.083 12.2 0.1 1.2 1 0 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase DUF4491 PF14898.6 CBK22868.2 - 0.059 13.8 0.7 0.059 13.8 0.7 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4491) MAP17 PF15807.5 CBK22868.2 - 0.18 12.1 1.1 0.33 11.2 1.1 1.4 1 0 0 1 1 1 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 WD40 PF00400.32 CBK22869.2 - 4.9e-24 84.1 11.1 1.5e-06 28.8 0.1 5.6 5 0 0 5 5 5 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBK22869.2 - 3.6e-10 40.0 0.0 0.048 14.0 0.0 3.9 2 1 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 CBK22869.2 - 0.017 14.1 0.0 2.7 6.9 0.0 2.9 2 1 1 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 CBK22869.2 - 0.019 14.9 0.1 18 5.2 0.0 3.2 2 1 1 3 3 3 0 Eukaryotic translation initiation factor eIF2A Rav1p_C PF12234.8 CBK22869.2 - 0.074 11.4 0.2 0.12 10.8 0.2 1.3 1 0 0 1 1 1 0 RAVE protein 1 C terminal Collagen PF01391.18 CBK22869.2 - 1.2 8.9 24.8 44 3.9 24.8 2.3 1 1 0 1 1 1 0 Collagen triple helix repeat (20 copies) RAM PF15320.6 CBK22869.2 - 2.6 8.7 6.7 5.9 7.6 6.7 1.6 1 0 0 1 1 1 0 mRNA cap methylation, RNMT-activating mini protein HLH PF00010.26 CBK22870.2 - 4e-09 36.3 4.0 1e-08 35.0 3.0 2.0 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain PAS_8 PF13188.7 CBK22870.2 - 0.014 15.4 0.0 0.032 14.2 0.0 1.7 1 1 0 1 1 1 0 PAS domain FAP206 PF12018.8 CBK22870.2 - 0.038 13.5 1.4 0.062 12.8 1.1 1.4 1 1 0 1 1 1 0 Domain of unknown function FliJ PF02050.16 CBK22870.2 - 0.04 14.1 4.2 0.058 13.6 4.2 1.2 1 0 0 1 1 1 0 Flagellar FliJ protein PAS_4 PF08448.10 CBK22870.2 - 0.089 13.0 0.0 0.23 11.7 0.0 1.7 2 0 0 2 2 2 0 PAS fold COG2 PF06148.11 CBK22870.2 - 0.25 11.4 2.3 0.34 11.0 1.2 1.7 1 1 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF2423 PF10338.9 CBK22870.2 - 0.74 10.1 3.3 0.42 10.9 0.7 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2423) PRKG1_interact PF15898.5 CBK22871.2 - 0.027 15.3 8.7 0.027 15.3 8.7 4.1 2 2 1 3 3 3 0 cGMP-dependent protein kinase interacting domain Filament PF00038.21 CBK22871.2 - 0.061 12.9 44.3 6.4 6.3 18.2 3.3 1 1 1 2 2 2 0 Intermediate filament protein Tup_N PF08581.10 CBK22871.2 - 0.092 13.1 0.5 0.092 13.1 0.5 4.7 3 1 0 3 3 3 0 Tup N-terminal DUF211 PF02680.14 CBK22871.2 - 0.1 12.8 0.0 0.25 11.5 0.0 1.7 1 0 0 1 1 1 0 Uncharacterized ArCR, COG1888 UPF0242 PF06785.11 CBK22871.2 - 0.19 11.8 50.2 0.075 13.1 18.6 3.0 1 1 2 3 3 3 0 Uncharacterised protein family (UPF0242) N-terminus ATG16 PF08614.11 CBK22871.2 - 0.58 10.3 52.1 0.041 14.1 17.7 3.1 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) GAS PF13851.6 CBK22871.2 - 1.4 8.2 44.0 4.8 6.5 24.0 2.5 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Spc7 PF08317.11 CBK22871.2 - 3 6.6 50.5 3.7 6.3 21.0 3.2 1 1 2 3 3 3 0 Spc7 kinetochore protein HrpB7 PF09486.10 CBK22871.2 - 5.3 7.4 45.1 0.83 10.0 26.5 3.0 1 1 1 2 2 2 0 Bacterial type III secretion protein (HrpB7) Histone PF00125.24 CBK22873.2 - 6.7e-53 178.5 2.8 7.5e-53 178.4 2.8 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 CBK22873.2 - 0.00011 22.5 0.1 0.00015 22.0 0.1 1.3 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 CBK22873.2 - 0.0005 20.2 0.1 0.00098 19.2 0.1 1.5 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold PAF PF15715.5 CBK22873.2 - 0.0011 19.6 0.9 0.0013 19.4 0.9 1.1 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CBFD_NFYB_HMF PF00808.23 CBK22873.2 - 0.019 15.2 0.0 0.039 14.2 0.0 1.5 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-T_C PF15511.6 CBK22874.2 - 2.6e-08 34.0 0.1 3.2e-08 33.7 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TAF PF02969.17 CBK22874.2 - 5.2e-05 23.3 0.1 8.2e-05 22.7 0.1 1.5 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) Histone PF00125.24 CBK22874.2 - 6.4e-05 23.3 0.1 9.8e-05 22.7 0.1 1.4 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 CBK22874.2 - 0.00022 21.5 0.1 0.0003 21.1 0.1 1.4 1 1 0 1 1 1 1 CENP-S protein CBFD_NFYB_HMF PF00808.23 CBK22874.2 - 0.00093 19.4 0.1 0.0017 18.6 0.0 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 CBK22874.2 - 0.01 15.9 0.0 0.012 15.7 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 CBK22874.2 - 0.025 14.6 0.0 0.036 14.1 0.0 1.2 1 0 0 1 1 1 0 Bromodomain associated Fer2 PF00111.27 CBK22875.2 - 3e-12 46.3 0.8 4.5e-12 45.8 0.8 1.2 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain DUF4457 PF14652.6 CBK22876.2 - 1.1e-13 51.2 0.0 1.4e-13 50.9 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4457) BrnT_toxin PF04365.13 CBK22877.2 - 0.097 13.0 0.0 0.2 12.0 0.0 1.6 1 0 0 1 1 1 0 Ribonuclease toxin, BrnT, of type II toxin-antitoxin system ABC_membrane PF00664.23 CBK22878.2 - 4.1e-48 164.4 31.0 2.2e-24 86.6 11.2 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 CBK22878.2 - 2.5e-47 160.8 0.1 1.1e-28 100.5 0.0 2.7 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 CBK22878.2 - 1.6e-07 31.0 8.4 7.2e-05 22.3 0.4 4.1 2 2 0 4 4 4 1 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 CBK22878.2 - 2.9e-05 24.1 2.1 0.13 12.3 0.1 3.0 2 0 0 2 2 2 2 50S ribosome-binding GTPase DEAD PF00270.29 CBK22878.2 - 9e-05 22.3 1.2 0.059 13.1 0.1 3.3 2 2 1 3 3 3 1 DEAD/DEAH box helicase AAA_29 PF13555.6 CBK22878.2 - 0.00035 20.3 0.4 0.23 11.2 0.0 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 CBK22878.2 - 0.0005 20.0 0.7 0.23 11.4 0.0 2.6 2 0 0 2 2 2 1 RsgA GTPase AAA_7 PF12775.7 CBK22878.2 - 0.0007 19.2 1.9 0.13 11.8 0.2 2.5 2 0 0 2 2 2 1 P-loop containing dynein motor region Dynamin_N PF00350.23 CBK22878.2 - 0.0012 18.9 5.4 0.13 12.3 0.5 3.9 3 1 0 3 3 3 1 Dynamin family DUF87 PF01935.17 CBK22878.2 - 0.0014 18.8 5.6 0.31 11.1 0.1 2.7 2 0 0 2 2 2 2 Helicase HerA, central domain Zeta_toxin PF06414.12 CBK22878.2 - 0.0039 16.5 0.3 0.087 12.1 0.1 2.6 2 0 0 2 2 2 1 Zeta toxin T2SSE PF00437.20 CBK22878.2 - 0.004 16.3 0.1 0.99 8.4 0.0 2.4 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA PF00004.29 CBK22878.2 - 0.0043 17.5 3.3 2.4 8.6 0.0 3.5 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 CBK22878.2 - 0.0079 16.5 3.7 2.7 8.3 0.1 3.8 4 1 0 4 4 2 1 AAA domain cobW PF02492.19 CBK22878.2 - 0.01 15.5 0.7 0.21 11.2 0.1 2.5 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_16 PF13191.6 CBK22878.2 - 0.012 16.0 0.5 0.39 11.1 0.0 2.5 2 1 0 2 2 2 0 AAA ATPase domain NB-ARC PF00931.22 CBK22878.2 - 0.013 14.7 0.7 0.96 8.6 0.0 2.6 2 1 0 2 2 2 0 NB-ARC domain AAA_25 PF13481.6 CBK22878.2 - 0.014 15.0 0.4 0.51 9.9 0.1 2.4 2 0 0 2 2 2 0 AAA domain DnaB_C PF03796.15 CBK22878.2 - 0.02 14.2 0.0 0.056 12.8 0.0 1.7 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain FtsK_SpoIIIE PF01580.18 CBK22878.2 - 0.029 13.7 2.1 2.4 7.4 0.3 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family TsaE PF02367.17 CBK22878.2 - 0.031 14.3 0.5 0.35 10.9 0.1 2.4 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_30 PF13604.6 CBK22878.2 - 0.035 13.8 3.0 5.1 6.8 0.3 2.8 3 0 0 3 3 3 0 AAA domain Septin PF00735.18 CBK22878.2 - 0.058 12.7 0.9 5.4 6.2 0.1 2.6 2 0 0 2 2 2 0 Septin AAA_24 PF13479.6 CBK22878.2 - 0.11 12.2 0.6 11 5.7 0.0 3.0 3 0 0 3 3 3 0 AAA domain RNA_helicase PF00910.22 CBK22878.2 - 0.13 12.7 3.4 29 5.1 0.0 4.1 4 0 0 4 4 4 0 RNA helicase MobB PF03205.14 CBK22878.2 - 0.15 12.0 0.7 1.6 8.6 0.1 2.4 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B ATP_bind_1 PF03029.17 CBK22878.2 - 0.17 11.6 7.9 2.3 7.9 1.6 3.0 3 0 0 3 3 2 0 Conserved hypothetical ATP binding protein IstB_IS21 PF01695.17 CBK22878.2 - 0.18 11.6 1.2 22 4.7 0.0 3.3 3 0 0 3 3 3 0 IstB-like ATP binding protein RseC_MucC PF04246.12 CBK22878.2 - 0.22 11.5 11.5 0.17 11.9 2.9 3.5 3 0 0 3 3 3 0 Positive regulator of sigma(E), RseC/MucC DUF2207 PF09972.9 CBK22878.2 - 0.36 9.5 13.3 1.7 7.3 3.5 3.2 3 1 0 3 3 3 0 Predicted membrane protein (DUF2207) NACHT PF05729.12 CBK22878.2 - 0.6 10.0 2.9 2.7 7.9 0.1 2.8 3 0 0 3 3 3 0 NACHT domain NTPase_1 PF03266.15 CBK22878.2 - 1.5 8.7 5.1 59 3.5 0.1 3.6 4 0 0 4 4 3 0 NTPase DUF1860 PF08949.10 CBK22881.2 - 0.026 14.3 0.7 0.058 13.1 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1860) KH_1 PF00013.29 CBK22882.2 - 7.2e-15 54.6 0.4 3.1e-10 39.7 0.2 2.6 2 0 0 2 2 2 2 KH domain KH_2 PF07650.17 CBK22882.2 - 0.00021 21.1 1.6 0.00087 19.1 1.3 2.4 1 1 1 2 2 2 1 KH domain SLS PF14611.6 CBK22882.2 - 0.0059 16.5 2.7 0.027 14.3 1.2 2.4 1 1 0 1 1 1 1 Mitochondrial inner-membrane-bound regulator MIS13 PF08202.11 CBK22882.2 - 0.0072 15.6 6.6 0.012 14.9 6.6 1.4 1 0 0 1 1 1 1 Mis12-Mtw1 protein family KH_5 PF13184.6 CBK22882.2 - 0.012 15.6 3.2 0.047 13.8 0.2 2.8 2 1 1 3 3 3 0 NusA-like KH domain SpoIISA_toxin PF14171.6 CBK22882.2 - 0.023 14.4 1.8 0.039 13.6 1.2 1.6 1 1 1 2 2 2 0 Toxin SpoIISA, type II toxin-antitoxin system HSBP1 PF06825.12 CBK22882.2 - 0.55 10.1 3.1 3.1 7.7 0.1 3.1 3 0 0 3 3 3 0 Heat shock factor binding protein 1 ABC_tran_CTD PF16326.5 CBK22882.2 - 3.2 8.1 10.1 1.6 9.0 1.2 3.4 3 1 0 3 3 3 0 ABC transporter C-terminal domain SOGA PF11365.8 CBK22882.2 - 3.5 8.8 14.6 9.3 7.5 4.3 3.0 1 1 1 2 2 2 0 Protein SOGA KH_1 PF00013.29 CBK22883.2 - 1.6e-30 104.8 1.7 8.4e-08 31.9 0.0 6.2 6 0 0 6 6 6 6 KH domain KH_2 PF07650.17 CBK22883.2 - 1.4e-08 34.4 1.8 0.027 14.3 0.1 3.6 3 0 0 3 3 3 2 KH domain SLS PF14611.6 CBK22883.2 - 3.7e-07 30.2 0.7 0.055 13.3 0.0 3.7 1 1 0 3 3 3 2 Mitochondrial inner-membrane-bound regulator KH_4 PF13083.6 CBK22883.2 - 0.00053 19.8 0.4 0.062 13.2 0.0 3.0 3 0 0 3 3 3 1 KH domain TolA PF06519.11 CBK22883.2 - 0.13 12.5 0.0 0.64 10.3 0.0 2.2 3 0 0 3 3 3 0 TolA C-terminal KH_5 PF13184.6 CBK22883.2 - 0.33 11.1 2.9 17 5.6 0.0 3.3 4 0 0 4 4 4 0 NusA-like KH domain Prefoldin_2 PF01920.20 CBK22885.2 - 9.6e-13 48.0 7.9 9.6e-13 48.0 7.9 1.6 1 1 1 2 2 2 1 Prefoldin subunit zf-MYND PF01753.18 CBK22885.2 - 7.7e-09 35.5 16.6 7.7e-09 35.5 16.6 1.9 2 0 0 2 2 2 1 MYND finger APG6_N PF17675.1 CBK22885.2 - 0.017 15.7 3.4 0.017 15.7 3.4 2.1 1 1 1 2 2 2 0 Apg6 coiled-coil region Cep57_CLD PF14073.6 CBK22885.2 - 0.053 13.5 12.8 0.068 13.2 12.8 1.1 1 0 0 1 1 1 0 Centrosome localisation domain of Cep57 Osmo_CC PF08946.10 CBK22885.2 - 0.053 13.8 0.8 0.12 12.7 0.8 1.6 1 0 0 1 1 1 0 Osmosensory transporter coiled coil DUF5320 PF17253.2 CBK22885.2 - 0.083 14.0 1.8 12 7.0 0.1 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5320) DUF3450 PF11932.8 CBK22885.2 - 0.22 10.8 10.4 0.93 8.7 1.8 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) Prefoldin PF02996.17 CBK22885.2 - 0.24 11.3 12.0 0.16 11.9 2.3 2.4 1 1 0 2 2 2 0 Prefoldin subunit DUF4200 PF13863.6 CBK22885.2 - 0.3 11.5 13.7 0.83 10.1 3.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) NPV_P10 PF05531.12 CBK22885.2 - 0.5 10.9 2.5 2.9 8.4 0.2 2.3 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein FlaC_arch PF05377.11 CBK22885.2 - 0.66 10.4 7.3 0.31 11.5 1.9 2.4 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) Laminin_II PF06009.12 CBK22885.2 - 0.72 9.9 8.0 2.1 8.3 0.6 2.1 1 1 0 2 2 2 0 Laminin Domain II DMPK_coil PF08826.10 CBK22885.2 - 1.2 9.3 9.1 0.19 11.8 1.5 2.3 2 0 0 2 2 2 0 DMPK coiled coil domain like DUF1664 PF07889.12 CBK22885.2 - 1.2 9.1 6.8 0.45 10.6 0.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Exonuc_VII_L PF02601.15 CBK22885.2 - 2.2 7.8 5.1 2.8 7.4 5.1 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit BLOC1_2 PF10046.9 CBK22885.2 - 2.5 8.5 12.3 0.7 10.2 2.0 2.4 2 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Seryl_tRNA_N PF02403.22 CBK22885.2 - 3.4 7.9 9.0 0.43 10.8 0.9 2.3 2 1 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Jnk-SapK_ap_N PF09744.9 CBK22885.2 - 3.5 7.8 12.9 2.3 8.5 1.5 2.1 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 GrpE PF01025.19 CBK22885.2 - 4 7.1 12.3 3.2 7.4 2.5 2.1 2 0 0 2 2 2 0 GrpE DUF4446 PF14584.6 CBK22885.2 - 5 7.1 9.6 2.3 8.2 1.9 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF4446) XhlA PF10779.9 CBK22885.2 - 8.3 6.7 8.0 1.1 9.5 2.0 2.4 2 1 1 3 3 3 0 Haemolysin XhlA Helicase_C PF00271.31 CBK22886.2 - 3.6e-12 46.6 0.1 1.1e-11 45.0 0.0 1.9 2 0 0 2 2 1 1 Helicase conserved C-terminal domain AAA_19 PF13245.6 CBK22886.2 - 4.3e-05 23.9 0.0 7.5e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain DEAD PF00270.29 CBK22886.2 - 4.9e-05 23.2 0.1 8.2e-05 22.4 0.1 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 CBK22886.2 - 0.0003 21.1 0.1 0.00088 19.6 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.6 CBK22886.2 - 0.00097 19.2 0.9 0.18 11.8 0.9 2.4 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 CBK22886.2 - 0.0021 17.8 0.0 0.0047 16.7 0.0 1.6 2 0 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.18 CBK22886.2 - 0.024 14.4 0.1 0.52 10.0 0.1 2.4 1 1 0 2 2 2 0 Viral (Superfamily 1) RNA helicase Helicase_RecD PF05127.14 CBK22886.2 - 0.029 14.2 0.0 0.054 13.3 0.0 1.5 1 0 0 1 1 1 0 Helicase ATPase_2 PF01637.18 CBK22886.2 - 0.03 14.2 0.2 0.049 13.5 0.2 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea ABC_tran PF00005.27 CBK22886.2 - 0.052 14.1 0.0 0.1 13.1 0.0 1.5 1 0 0 1 1 1 0 ABC transporter AAA_11 PF13086.6 CBK22886.2 - 0.083 12.7 0.0 0.19 11.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 CBK22886.2 - 0.095 12.4 0.2 2.3 7.9 0.0 2.5 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_7 PF12775.7 CBK22886.2 - 0.11 12.0 0.1 0.39 10.2 0.0 1.9 1 1 1 2 2 2 0 P-loop containing dynein motor region ATPase PF06745.13 CBK22886.2 - 0.12 11.8 0.2 0.36 10.1 0.2 1.9 1 1 0 1 1 1 0 KaiC Stc1 PF12898.7 CBK22887.2 - 0.00051 20.5 5.3 0.00062 20.3 5.3 1.1 1 0 0 1 1 1 1 Stc1 domain He_PIG PF05345.12 CBK22888.2 - 3.1e-11 43.3 0.0 2.3e-05 24.5 0.0 2.5 2 0 0 2 2 2 2 Putative Ig domain DUF1129 PF06570.11 CBK22888.2 - 0.14 11.7 0.0 0.27 10.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) SNF2_N PF00176.23 CBK22889.2 - 3.6e-71 239.7 3.1 1.2e-70 238.0 3.2 1.7 1 1 1 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 CBK22889.2 - 2.9e-20 72.7 0.0 3.7e-19 69.1 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 CBK22889.2 - 4.4e-09 36.6 0.0 6.6e-08 32.7 0.0 2.9 3 1 1 4 4 4 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 CBK22889.2 - 6e-09 35.5 0.2 1.4e-08 34.2 0.2 1.6 1 0 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 DEAD PF00270.29 CBK22889.2 - 4.7e-08 33.0 0.1 2.8e-07 30.5 0.0 2.4 3 0 0 3 3 3 1 DEAD/DEAH box helicase ERCC3_RAD25_C PF16203.5 CBK22889.2 - 0.0075 15.5 0.0 0.017 14.3 0.0 1.6 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase SWI2_SNF2 PF18766.1 CBK22889.2 - 0.029 14.0 0.1 0.19 11.3 0.0 2.2 2 0 0 2 2 2 0 SWI2/SNF2 ATPase Myb_DNA-binding PF00249.31 CBK22889.2 - 0.13 12.5 0.0 0.79 10.0 0.0 2.4 1 1 0 1 1 1 0 Myb-like DNA-binding domain SirA PF10747.9 CBK22889.2 - 0.49 10.7 2.8 0.41 11.0 0.3 2.2 3 0 0 3 3 3 0 Sporulation inhibitor of replication protein SirA Ribosomal_S26e PF01283.19 CBK22890.2 - 4.5e-44 149.3 6.9 5e-44 149.2 6.9 1.0 1 0 0 1 1 1 1 Ribosomal protein S26e Fer4_7 PF12838.7 CBK22890.2 - 0.00083 19.9 0.8 0.077 13.6 0.2 2.2 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_6 PF12837.7 CBK22890.2 - 0.0069 16.4 2.9 0.042 13.9 0.8 2.2 2 0 0 2 2 2 1 4Fe-4S binding domain SRP19 PF01922.17 CBK22890.2 - 0.0076 17.2 0.2 0.011 16.7 0.2 1.3 1 0 0 1 1 1 1 SRP19 protein RNA_pol_N PF01194.17 CBK22890.2 - 0.032 14.5 2.0 0.06 13.6 2.0 1.5 1 1 0 1 1 1 0 RNA polymerases N / 8 kDa subunit Fer4_2 PF12797.7 CBK22890.2 - 0.045 13.9 3.4 0.14 12.3 1.1 2.2 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4 PF00037.27 CBK22890.2 - 0.081 12.8 3.5 0.1 12.4 0.8 2.1 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_4 PF12800.7 CBK22890.2 - 0.89 10.2 7.3 0.64 10.7 2.6 2.2 2 0 0 2 2 2 0 4Fe-4S binding domain MAP65_ASE1 PF03999.12 CBK22891.2 - 3e-08 32.8 5.5 3.2e-08 32.7 5.5 1.0 1 0 0 1 1 1 1 Microtubule associated protein (MAP65/ASE1 family) FeoB_Cyto PF17910.1 CBK22891.2 - 0.014 15.9 1.5 0.064 13.8 0.2 2.1 1 1 1 2 2 2 0 FeoB cytosolic helical domain YkyA PF10368.9 CBK22891.2 - 0.58 9.8 7.2 1.3 8.6 7.2 1.5 1 1 0 1 1 1 0 Putative cell-wall binding lipoprotein MAP65_ASE1 PF03999.12 CBK22892.2 - 5.5e-15 55.1 2.7 6.4e-15 54.9 2.7 1.0 1 0 0 1 1 1 1 Microtubule associated protein (MAP65/ASE1 family) ALIX_LYPXL_bnd PF13949.6 CBK22892.2 - 0.0063 15.8 0.3 0.0071 15.7 0.3 1.1 1 0 0 1 1 1 1 ALIX V-shaped domain binding to HIV Cucumopine_C PF18631.1 CBK22892.2 - 0.011 15.6 0.1 0.09 12.7 0.1 2.1 1 1 1 2 2 2 0 Cucumopine synthase C-terminal helical bundle domain Atypical_Card PF18461.1 CBK22892.2 - 0.037 14.2 0.7 0.15 12.3 0.2 1.9 1 1 1 2 2 2 0 Atypical caspase recruitment domain Flt3_lig PF02947.14 CBK22892.2 - 0.069 13.3 0.9 0.097 12.9 0.9 1.2 1 0 0 1 1 1 0 flt3 ligand Baculo_PEP_C PF04513.12 CBK22892.2 - 0.077 13.0 3.3 0.05 13.6 1.4 1.7 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus CT_C_D PF02682.16 CBK22892.2 - 0.18 11.5 0.0 0.28 10.9 0.0 1.3 1 0 0 1 1 1 0 Carboxyltransferase domain, subdomain C and D Hormone_recep PF00104.30 CBK22892.2 - 0.25 10.9 3.7 0.54 9.8 0.2 2.1 1 1 1 2 2 2 0 Ligand-binding domain of nuclear hormone receptor ATP-synt_C PF00137.21 CBK22893.2 - 7.5e-24 83.9 19.8 2.6e-13 50.1 10.7 2.4 2 0 0 2 2 2 2 ATP synthase subunit C SLATT_5 PF18160.1 CBK22893.2 - 0.81 9.0 3.2 2.7 7.3 0.4 2.5 2 1 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain family 5 YEATS PF03366.16 CBK22894.2 - 4.6e-29 100.2 0.1 6e-29 99.9 0.1 1.2 1 0 0 1 1 1 1 YEATS family Fe_hyd_SSU PF02256.17 CBK22894.2 - 0.044 13.9 0.2 0.079 13.1 0.2 1.4 1 0 0 1 1 1 0 Iron hydrogenase small subunit Cyclophil_like PF04126.13 CBK22894.2 - 0.12 12.2 0.0 0.19 11.6 0.0 1.3 1 0 0 1 1 1 0 Cyclophilin-like UCH PF00443.29 CBK22895.2 - 4e-45 154.3 0.0 4.9e-45 154.0 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 CBK22895.2 - 6.9e-09 35.7 0.2 2.3e-07 30.7 0.2 2.4 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Peptidase_C98 PF15499.6 CBK22895.2 - 0.11 12.0 0.0 0.38 10.2 0.0 1.8 2 0 0 2 2 2 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase DKCLD PF08068.12 CBK22896.2 - 1e-32 112.0 1.6 8.3e-32 109.1 0.5 2.7 3 0 0 3 3 3 1 DKCLD (NUC011) domain TruB_C_2 PF16198.5 CBK22896.2 - 1.8e-21 76.1 0.6 3.7e-21 75.0 0.6 1.6 1 0 0 1 1 1 1 tRNA pseudouridylate synthase B C-terminal domain PUA PF01472.20 CBK22896.2 - 3.7e-21 74.9 1.7 7.7e-21 73.8 1.7 1.6 1 0 0 1 1 1 1 PUA domain TruB_N PF01509.18 CBK22896.2 - 3.4e-20 72.9 7.7 2.8e-19 70.0 0.1 3.8 2 1 0 2 2 1 1 TruB family pseudouridylate synthase (N terminal domain) UPF0113 PF03657.13 CBK22896.2 - 0.00035 20.8 0.1 0.0014 18.8 0.0 2.1 2 0 0 2 2 2 1 UPF0113 PUA domain Coilin_N PF15862.5 CBK22896.2 - 0.00083 19.2 16.6 0.0016 18.3 16.6 1.6 1 0 0 1 1 1 1 Coilin N-terminus GAGA_bind PF06217.12 CBK22896.2 - 1.3 9.3 18.7 1.9 8.7 18.7 1.3 1 0 0 1 1 1 0 GAGA binding protein-like family DDHD PF02862.17 CBK22896.2 - 1.8 8.7 8.8 2.9 8.0 8.8 1.4 1 0 0 1 1 1 0 DDHD domain RR_TM4-6 PF06459.12 CBK22896.2 - 1.8 8.3 30.4 2.7 7.8 30.4 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 SAPS PF04499.15 CBK22896.2 - 2.4 6.8 12.3 3.3 6.4 12.3 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DUF913 PF06025.12 CBK22896.2 - 4.3 6.2 11.1 6.2 5.7 11.1 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) AAA_11 PF13086.6 CBK22896.2 - 5 6.8 15.5 9.1 6.0 15.5 1.4 1 0 0 1 1 1 0 AAA domain RNA_pol_Rpc4 PF05132.14 CBK22896.2 - 5.5 7.4 22.6 13 6.2 22.6 1.7 1 0 0 1 1 1 0 RNA polymerase III RPC4 zf-C2H2 PF00096.26 CBK22897.2 - 3.3e-24 83.9 40.3 7.8e-07 29.2 1.6 5.1 5 0 0 5 5 5 5 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 CBK22897.2 - 2.6e-23 81.3 37.2 1.5e-06 28.3 0.4 6.1 6 0 0 6 6 6 4 Zinc-finger double domain zf-C2H2_4 PF13894.6 CBK22897.2 - 4.9e-20 70.5 38.0 4.4e-05 24.0 1.0 5.1 5 0 0 5 5 5 5 C2H2-type zinc finger zf-Di19 PF05605.12 CBK22897.2 - 3.7e-07 30.3 17.3 0.00054 20.2 0.1 4.0 2 1 1 4 4 4 3 Drought induced 19 protein (Di19), zinc-binding zf-met PF12874.7 CBK22897.2 - 1.5e-06 28.3 23.0 0.1 13.0 0.3 5.4 5 0 0 5 5 5 4 Zinc-finger of C2H2 type zf-C2H2_9 PF16293.5 CBK22897.2 - 1.6e-05 24.6 5.0 0.17 11.7 0.0 4.0 3 1 1 4 4 4 2 C2H2 type zinc-finger (1 copy) zf-H2C2_5 PF13909.6 CBK22897.2 - 4.6e-05 23.1 26.5 0.0026 17.5 0.1 5.7 5 1 0 5 5 5 2 C2H2-type zinc-finger domain zf-TRAF PF02176.18 CBK22897.2 - 0.0003 21.4 19.0 0.18 12.5 6.1 3.3 1 1 3 4 4 4 3 TRAF-type zinc finger zf-C2H2_aberr PF17017.5 CBK22897.2 - 0.0011 19.1 17.8 0.002 18.3 0.6 3.7 2 2 2 4 4 4 2 Aberrant zinc-finger zf-C2H2_6 PF13912.6 CBK22897.2 - 0.0022 17.9 1.2 0.0022 17.9 1.2 5.0 5 0 0 5 5 5 2 C2H2-type zinc finger zf_Hakai PF18408.1 CBK22897.2 - 0.006 16.3 18.4 0.35 10.6 0.2 4.6 5 0 0 5 5 5 2 C2H2 Hakai zinc finger domain zf-BED PF02892.15 CBK22897.2 - 0.018 15.1 0.8 0.018 15.1 0.8 4.1 3 1 1 4 4 4 0 BED zinc finger DUF2172 PF09940.9 CBK22897.2 - 0.022 15.2 1.0 0.068 13.6 0.2 2.1 1 1 2 3 3 3 0 Domain of unknown function (DUF2172) zf-C2H2_3rep PF18868.1 CBK22897.2 - 0.031 14.9 14.0 0.94 10.2 2.0 3.7 1 1 1 2 2 2 0 Zinc finger C2H2-type, 3 repeats zf-C2H2_jaz PF12171.8 CBK22897.2 - 0.037 14.3 33.0 0.19 12.1 1.0 5.3 5 0 0 5 5 5 0 Zinc-finger double-stranded RNA-binding GAGA PF09237.11 CBK22897.2 - 0.04 13.7 3.9 1.9 8.4 0.0 3.1 3 1 0 3 3 3 0 GAGA factor Zn-C2H2_12 PF18112.1 CBK22897.2 - 0.046 14.2 11.0 3.7 8.1 0.2 5.2 5 0 0 5 5 5 0 Autophagy receptor zinc finger-C2H2 domain zf-C2HC_2 PF13913.6 CBK22897.2 - 0.057 13.3 20.3 0.86 9.6 0.2 4.7 4 0 0 4 4 4 0 zinc-finger of a C2HC-type zf-C2H2_2 PF12756.7 CBK22897.2 - 0.12 12.7 21.3 1.4 9.3 0.2 4.2 1 1 1 3 3 3 0 C2H2 type zinc-finger (2 copies) FOXP-CC PF16159.5 CBK22897.2 - 0.12 13.0 9.6 18 6.1 0.2 4.2 2 2 2 4 4 4 0 FOXP coiled-coil domain zinc_ribbon_15 PF17032.5 CBK22897.2 - 0.44 11.3 12.9 1.1 10.0 2.5 2.6 1 1 1 2 2 2 0 zinc-ribbon family zf-C2H2_8 PF15909.5 CBK22897.2 - 0.47 10.8 15.0 0.45 10.8 6.8 2.4 1 1 1 2 2 2 0 C2H2-type zinc ribbon zf-Sec23_Sec24 PF04810.15 CBK22897.2 - 0.54 10.4 8.7 4.1 7.5 0.1 3.7 3 1 0 3 3 3 0 Sec23/Sec24 zinc finger ROS_MUCR PF05443.11 CBK22897.2 - 0.72 9.9 8.5 2.7 8.1 0.1 3.3 1 1 1 3 3 3 0 ROS/MUCR transcriptional regulator protein Opiods_neuropep PF01160.18 CBK22897.2 - 2.3 8.4 7.8 0.5 10.5 0.7 3.3 2 1 2 4 4 3 0 Vertebrate endogenous opioids neuropeptide zf-C4_ClpX PF06689.13 CBK22897.2 - 4.1 7.4 10.3 2.3 8.2 0.5 3.4 3 0 0 3 3 3 0 ClpX C4-type zinc finger Tam41_Mmp37 PF09139.11 CBK22898.2 - 6.3e-100 334.7 0.0 7.2e-100 334.6 0.0 1.0 1 0 0 1 1 1 1 Phosphatidate cytidylyltransferase, mitochondrial Gon7 PF08738.10 CBK22899.2 - 0.00062 19.8 0.7 0.00062 19.8 0.7 2.1 2 0 0 2 2 2 1 Gon7 family Spc24 PF08286.11 CBK22899.2 - 0.015 15.6 7.1 0.24 11.7 1.7 2.2 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 TSC22 PF01166.18 CBK22899.2 - 0.015 15.6 1.4 2.7 8.4 0.1 2.5 2 0 0 2 2 2 0 TSC-22/dip/bun family CorA PF01544.18 CBK22899.2 - 0.03 13.6 3.3 0.041 13.2 3.3 1.2 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein PAXX PF15384.6 CBK22899.2 - 0.044 13.5 1.3 0.052 13.2 1.3 1.2 1 0 0 1 1 1 0 PAXX, PAralog of XRCC4 and XLF, also called C9orf142 DUF4446 PF14584.6 CBK22899.2 - 0.056 13.4 1.8 0.088 12.8 0.3 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF4446) Csm1_N PF18504.1 CBK22899.2 - 0.061 13.7 10.0 0.79 10.1 1.5 2.5 2 0 0 2 2 2 0 Csm1 N-terminal domain DUF4795 PF16043.5 CBK22899.2 - 0.078 12.6 6.2 0.3 10.7 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4795) Noelin-1 PF12308.8 CBK22899.2 - 0.11 12.5 3.2 0.26 11.3 0.2 2.2 2 0 0 2 2 2 0 Neurogenesis glycoprotein Hairy_orange PF07527.13 CBK22899.2 - 0.13 12.5 0.4 0.33 11.2 0.2 1.8 2 0 0 2 2 1 0 Hairy Orange DUF3573 PF12097.8 CBK22899.2 - 0.16 10.7 6.3 0.06 12.2 0.4 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3573) Prefoldin PF02996.17 CBK22899.2 - 0.27 11.1 3.2 2 8.3 0.1 2.3 2 0 0 2 2 2 0 Prefoldin subunit RmuC PF02646.16 CBK22899.2 - 0.3 10.2 6.2 1.2 8.1 0.7 2.1 2 0 0 2 2 2 0 RmuC family DUF948 PF06103.11 CBK22899.2 - 0.31 11.3 2.5 1.1 9.5 0.2 2.4 2 2 0 2 2 2 0 Bacterial protein of unknown function (DUF948) DUF3138 PF11336.8 CBK22899.2 - 0.42 9.2 2.1 3.9 6.0 0.4 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3138) GAS PF13851.6 CBK22899.2 - 0.47 9.8 8.3 0.62 9.4 0.9 2.1 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding TolA_bind_tri PF16331.5 CBK22899.2 - 0.67 10.1 12.2 3.8 7.7 0.6 2.4 2 0 0 2 2 2 0 TolA binding protein trimerisation DUF4763 PF15960.5 CBK22899.2 - 0.79 9.0 10.7 0.066 12.5 0.9 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4763) YabA PF06156.13 CBK22899.2 - 0.85 10.3 7.0 1 10.0 0.7 2.3 1 1 1 2 2 2 0 Initiation control protein YabA APG6_N PF17675.1 CBK22899.2 - 1.2 9.7 9.5 5.1 7.6 1.7 2.2 2 0 0 2 2 2 0 Apg6 coiled-coil region SlyX PF04102.12 CBK22899.2 - 1.4 9.6 13.3 1.3 9.6 1.6 2.6 2 1 0 2 2 2 0 SlyX DUF4407 PF14362.6 CBK22899.2 - 1.4 8.2 5.4 4.9 6.4 5.2 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Med3 PF11593.8 CBK22899.2 - 1.5 7.9 3.9 0.73 9.0 0.4 1.7 1 1 1 2 2 2 0 Mediator complex subunit 3 fungal HAUS-augmin3 PF14932.6 CBK22899.2 - 1.5 8.3 13.1 1.2 8.6 2.9 2.0 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 3 CLZ PF16526.5 CBK22899.2 - 1.8 8.9 8.9 0.95 9.9 0.8 2.9 2 2 1 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Fib_alpha PF08702.10 CBK22899.2 - 1.9 8.7 7.2 5.2 7.2 7.2 1.8 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family ATG16 PF08614.11 CBK22899.2 - 1.9 8.7 12.4 3.1 8.0 2.4 2.2 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) ZapB PF06005.12 CBK22899.2 - 2 8.9 10.4 2 8.9 1.6 2.4 1 1 1 2 2 2 0 Cell division protein ZapB GIT_CC PF16559.5 CBK22899.2 - 2.1 8.3 12.9 1.3 8.9 3.9 2.7 2 1 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor DUF5082 PF16888.5 CBK22899.2 - 3.4 8.0 9.5 12 6.2 1.3 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF5082) DivIC PF04977.15 CBK22899.2 - 3.7 7.4 10.3 2.5 7.9 0.9 2.9 1 1 1 2 2 2 0 Septum formation initiator ADIP PF11559.8 CBK22899.2 - 3.7 7.6 14.7 1.4 9.0 1.8 2.6 2 1 0 2 2 2 0 Afadin- and alpha -actinin-Binding EMP24_GP25L PF01105.24 CBK22899.2 - 3.8 7.4 8.3 1.1 9.2 2.9 2.0 1 1 1 2 2 2 0 emp24/gp25L/p24 family/GOLD FlaC_arch PF05377.11 CBK22899.2 - 4.3 7.8 5.2 8.9 6.8 1.9 2.5 2 2 0 2 2 2 0 Flagella accessory protein C (FlaC) Sec2p PF06428.11 CBK22899.2 - 4.5 7.3 9.5 1.8 8.6 2.5 2.3 2 0 0 2 2 2 0 GDP/GTP exchange factor Sec2p betaPIX_CC PF16523.5 CBK22899.2 - 5.9 6.8 7.8 7.2 6.5 0.2 2.7 2 1 1 3 3 3 0 betaPIX coiled coil RasGAP_C PF03836.15 CBK22899.2 - 6.6 6.9 12.6 4.6e+02 0.9 12.6 2.2 1 1 0 1 1 1 0 RasGAP C-terminus WASH_WAHD PF11945.8 CBK22900.2 - 9.3e-06 25.4 0.1 9.3e-06 25.4 0.1 2.0 2 0 0 2 2 2 1 WAHD domain of WASH complex DUF4298 PF14131.6 CBK22900.2 - 0.22 11.5 1.0 0.85 9.6 0.2 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4298) Ribosomal_L11_N PF03946.14 CBK22901.2 - 4.1e-18 65.0 0.5 6.6e-18 64.3 0.5 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.19 CBK22901.2 - 5.3e-17 62.1 0.0 8.5e-17 61.4 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain RNA_pol_Rpb8 PF03870.15 CBK22902.2 - 3.3e-44 150.4 0.9 3.7e-44 150.3 0.9 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb8 RNA_pol_RpbG PF16992.5 CBK22902.2 - 2.1e-06 27.8 1.0 1.3e-05 25.3 0.6 1.9 1 1 1 2 2 2 1 DNA-directed RNA polymerase, subunit G Ribosomal_L31e PF01198.19 CBK22903.2 - 3.1e-33 113.9 0.3 4e-33 113.5 0.3 1.1 1 0 0 1 1 1 1 Ribosomal protein L31e PPTA PF01239.22 CBK22904.2 - 3e-06 26.8 1.9 0.024 14.3 0.1 3.2 3 0 0 3 3 3 2 Protein prenyltransferase alpha subunit repeat C2 PF00168.30 CBK22905.2 - 2.6e-07 30.9 0.0 4.2e-07 30.2 0.0 1.3 1 0 0 1 1 1 1 C2 domain Ribosomal_S15 PF00312.22 CBK22906.2 - 0.12 12.6 0.5 2.3 8.5 0.2 2.2 1 1 1 2 2 2 0 Ribosomal protein S15 RRM_1 PF00076.22 CBK22907.2 - 2.1e-05 24.3 0.0 5.7e-05 22.9 0.0 1.8 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-C2H2_10 PF16588.5 CBK22907.2 - 0.045 13.5 1.3 0.11 12.3 1.3 1.6 1 0 0 1 1 1 0 C2H2 zinc-finger Ribosomal_S9 PF00380.19 CBK22908.2 - 5.7e-31 107.5 0.3 6.6e-31 107.4 0.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S9/S16 Adaptin_N PF01602.20 CBK22910.2 - 9.7e-43 146.5 10.5 1.3e-42 146.1 10.5 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 CBK22910.2 - 9.9e-11 41.9 0.4 9.9e-11 41.9 0.4 3.5 2 1 1 4 4 4 1 non-SMC mitotic condensation complex subunit 1 DUF1368 PF07112.11 CBK22911.2 - 0.084 11.7 0.5 0.11 11.3 0.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1368) SOP4 PF17081.5 CBK22913.2 - 0.032 13.8 0.7 0.057 13.0 0.7 1.3 1 0 0 1 1 1 0 Suppressor of PMA 1-7 protein Inhibitor_I29 PF08246.12 CBK22913.2 - 0.094 13.2 0.3 0.094 13.2 0.3 2.0 2 0 0 2 2 2 0 Cathepsin propeptide inhibitor domain (I29) GRIM-19 PF06212.12 CBK22914.2 - 6e-31 107.1 0.1 6.6e-31 107.0 0.1 1.0 1 0 0 1 1 1 1 GRIM-19 protein DUF1206 PF06724.11 CBK22914.2 - 0.093 12.8 0.4 0.13 12.4 0.4 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1206) dCMP_cyt_deam_2 PF08211.12 CBK22915.2 - 2.2e-20 73.2 0.0 2.6e-16 60.0 0.0 2.2 2 0 0 2 2 2 2 Cytidine and deoxycytidylate deaminase zinc-binding region dCMP_cyt_deam_1 PF00383.23 CBK22915.2 - 1.2e-11 44.3 0.1 3.3e-11 42.9 0.1 1.6 2 0 0 2 2 2 1 Cytidine and deoxycytidylate deaminase zinc-binding region SNAD4 PF18750.1 CBK22915.2 - 0.00066 19.8 0.1 0.0015 18.6 0.1 1.5 1 0 0 1 1 1 1 Secreted Novel AID/APOBEC-like Deaminase 4 NAD1 PF18778.1 CBK22915.2 - 0.016 15.3 0.0 0.028 14.5 0.0 1.3 1 0 0 1 1 1 0 Novel AID APOBEC clade 1 MafB19-deam PF14437.6 CBK22915.2 - 0.026 14.3 0.1 0.046 13.5 0.1 1.4 1 0 0 1 1 1 0 MafB19-like deaminase APOBEC2 PF18772.1 CBK22915.2 - 0.09 12.8 0.0 0.14 12.2 0.0 1.3 1 0 0 1 1 1 0 APOBEC2 Spc7 PF08317.11 CBK22916.2 - 0.053 12.4 20.0 0.41 9.5 19.8 2.1 1 1 0 1 1 1 0 Spc7 kinetochore protein Seryl_tRNA_N PF02403.22 CBK22916.2 - 0.092 13.0 15.0 0.44 10.8 0.5 2.6 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DUF1664 PF07889.12 CBK22916.2 - 0.39 10.8 10.8 0.55 10.3 0.8 2.5 1 1 0 2 2 2 0 Protein of unknown function (DUF1664) APG6_N PF17675.1 CBK22916.2 - 0.63 10.6 24.4 0.24 12.0 6.6 2.5 1 1 1 2 2 2 0 Apg6 coiled-coil region YabA PF06156.13 CBK22916.2 - 1.3 9.7 8.6 0.31 11.7 0.8 2.9 1 1 2 3 3 3 0 Initiation control protein YabA GAS PF13851.6 CBK22916.2 - 1.7 8.0 17.5 3.7 6.8 9.8 2.5 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding YlqD PF11068.8 CBK22916.2 - 1.7 9.0 18.0 57 4.1 8.8 2.8 1 1 1 2 2 2 0 YlqD protein Syntaxin-6_N PF09177.11 CBK22916.2 - 2 9.0 14.2 0.47 11.0 5.1 3.0 1 1 2 3 3 3 0 Syntaxin 6, N-terminal ADIP PF11559.8 CBK22916.2 - 2.1 8.4 17.4 3.3 7.8 5.6 2.8 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding DUF5595 PF18077.1 CBK22916.2 - 3 8.0 7.4 2.2 8.4 2.4 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF5595) SKA2 PF16740.5 CBK22916.2 - 3.2 7.6 11.3 4.2 7.2 0.2 3.2 2 2 1 3 3 3 0 Spindle and kinetochore-associated protein 2 DUF5082 PF16888.5 CBK22916.2 - 3.8 7.8 16.0 8.8 6.6 7.5 3.1 1 1 2 3 3 3 0 Domain of unknown function (DUF5082) Phage_GPO PF05929.11 CBK22916.2 - 5.3 6.6 14.8 0.29 10.7 3.8 2.3 1 1 1 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase Cortex-I_coil PF09304.10 CBK22916.2 - 5.9 7.2 13.8 2.7 8.3 3.7 2.4 1 1 0 2 2 2 0 Cortexillin I, coiled coil Prominin PF05478.11 CBK22916.2 - 9.4 4.0 8.7 6.3 4.6 4.1 1.9 1 1 1 2 2 2 0 Prominin UQ_con PF00179.26 CBK22917.2 - 2e-38 131.2 0.0 2.3e-38 131.0 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 CBK22917.2 - 8.6e-05 22.3 0.0 0.0001 22.0 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 CBK22917.2 - 0.023 15.0 0.0 0.031 14.6 0.0 1.4 1 1 0 1 1 1 0 RWD domain UQ_con PF00179.26 CBK22918.2 - 3.7e-44 149.8 0.1 4.1e-44 149.6 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme CSD PF00313.22 CBK22919.2 - 0.0096 15.7 0.0 0.015 15.2 0.0 1.3 1 0 0 1 1 1 1 'Cold-shock' DNA-binding domain MatE PF01554.18 CBK22920.2 - 5.2e-29 101.0 29.8 2.2e-19 69.7 4.5 3.5 3 1 1 4 4 4 2 MatE Polysacc_synt_C PF14667.6 CBK22920.2 - 0.0016 18.5 28.6 0.0027 17.8 14.6 3.3 3 1 0 3 3 3 2 Polysaccharide biosynthesis C-terminal domain RNA_pol_Rpb1_5 PF04998.17 CBK22921.2 - 3.4e-87 292.3 0.0 5e-87 291.7 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_1 PF04997.12 CBK22921.2 - 5.2e-74 249.4 0.6 9.3e-74 248.6 0.6 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_2 PF00623.20 CBK22921.2 - 3.4e-72 242.1 0.0 8.8e-72 240.7 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.18 CBK22921.2 - 1.7e-33 115.8 0.0 4.2e-33 114.5 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.17 CBK22921.2 - 2.1e-27 95.2 0.0 2.1e-27 95.2 0.0 2.5 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 4 Fer2 PF00111.27 CBK22921.2 - 4.6e-09 36.1 5.2 4.7e-09 36.1 2.9 2.2 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain AF-4 PF05110.13 CBK22921.2 - 1.1 7.2 9.3 1.6 6.7 9.3 1.0 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Macoilin PF09726.9 CBK22921.2 - 3.6 6.0 5.3 6.5 5.2 5.3 1.3 1 0 0 1 1 1 0 Macoilin family KH_6 PF15985.5 CBK22924.2 - 2.5e-13 50.2 0.0 8.1e-13 48.5 0.0 1.8 2 0 0 2 2 2 1 KH domain Ribosomal_S13_N PF08069.12 CBK22925.2 - 2.7e-29 101.0 0.3 6.9e-29 99.7 0.1 1.8 2 0 0 2 2 2 1 Ribosomal S13/S15 N-terminal domain Ribosomal_S15 PF00312.22 CBK22925.2 - 7.1e-16 58.2 0.8 9.1e-16 57.8 0.8 1.2 1 0 0 1 1 1 1 Ribosomal protein S15 zf-CCHC PF00098.23 CBK22926.2 - 4.6e-57 187.7 59.6 2.3e-09 36.9 1.5 7.1 7 0 0 7 7 7 7 Zinc knuckle zf-CCHC_2 PF13696.6 CBK22926.2 - 1.8e-20 72.4 57.5 3.2e-06 26.8 2.1 7.5 7 0 0 7 7 7 7 Zinc knuckle zf-CCHC_4 PF14392.6 CBK22926.2 - 2.3e-12 46.5 41.3 0.0047 16.6 1.1 7.0 7 0 0 7 7 7 7 Zinc knuckle zf-CCHC_3 PF13917.6 CBK22926.2 - 3.6e-12 46.0 40.5 0.046 13.7 0.3 7.1 2 2 5 7 7 7 6 Zinc knuckle zf-CCHC_6 PF15288.6 CBK22926.2 - 1.1e-06 28.3 51.1 0.002 18.0 0.9 7.1 5 2 2 7 7 7 6 Zinc knuckle zf-CCHC_5 PF14787.6 CBK22926.2 - 3.3e-05 23.5 52.2 0.26 11.0 0.2 7.1 4 1 3 7 7 7 7 GAG-polyprotein viral zinc-finger DUF2304 PF10066.9 CBK22927.2 - 0.012 15.8 4.9 0.076 13.2 3.1 2.1 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2304) DUF2070 PF09843.9 CBK22927.2 - 1.3 7.2 6.6 1.4 7.1 6.6 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) CDP-OH_P_transf PF01066.21 CBK22928.2 - 2.5e-17 63.4 0.5 2.5e-17 63.4 0.5 2.9 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase Ndc1_Nup PF09531.10 CBK22928.2 - 3.8 6.1 5.2 5.5 5.6 5.2 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup HSP70 PF00012.20 CBK22929.2 - 2.2e-83 280.4 0.0 1.5e-69 234.8 0.0 2.1 2 0 0 2 2 2 2 Hsp70 protein MreB_Mbl PF06723.13 CBK22929.2 - 1e-11 44.2 0.0 2.1e-11 43.2 0.0 1.4 1 0 0 1 1 1 1 MreB/Mbl protein FtsA PF14450.6 CBK22929.2 - 0.00016 22.0 0.1 0.012 16.0 0.0 2.5 2 0 0 2 2 2 1 Cell division protein FtsA StbA PF06406.11 CBK22929.2 - 0.13 11.5 0.0 0.4 9.9 0.0 1.8 2 0 0 2 2 2 0 StbA protein PH PF00169.29 CBK22930.2 - 0.00069 20.1 0.2 0.0049 17.4 0.2 2.0 1 1 0 1 1 1 1 PH domain DUF1647 PF07801.11 CBK22931.2 - 0.21 11.4 1.2 0.91 9.3 1.2 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF1647) Ribosomal_L22 PF00237.19 CBK22932.2 - 3.8e-33 113.8 0.2 6.1e-33 113.1 0.2 1.3 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e Rad51 PF08423.11 CBK22933.2 - 2.4e-121 403.8 0.0 3.4e-121 403.3 0.0 1.2 1 0 0 1 1 1 1 Rad51 RecA PF00154.21 CBK22933.2 - 3.5e-12 46.3 0.1 5.4e-12 45.7 0.1 1.3 1 0 0 1 1 1 1 recA bacterial DNA recombination protein AAA_25 PF13481.6 CBK22933.2 - 1.8e-08 34.2 0.0 2.8e-08 33.6 0.0 1.2 1 0 0 1 1 1 1 AAA domain ATPase PF06745.13 CBK22933.2 - 3.8e-06 26.4 0.0 7.9e-06 25.4 0.0 1.6 1 1 0 1 1 1 1 KaiC DnaB_C PF03796.15 CBK22933.2 - 3.3e-05 23.3 0.0 0.0038 16.6 0.0 2.3 2 0 0 2 2 2 2 DnaB-like helicase C terminal domain HHH_5 PF14520.6 CBK22933.2 - 5e-05 23.8 1.0 0.00011 22.7 1.0 1.5 1 0 0 1 1 1 1 Helix-hairpin-helix domain AAA_24 PF13479.6 CBK22933.2 - 0.00021 21.1 0.0 0.0004 20.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain PAXNEB PF05625.11 CBK22933.2 - 0.0041 16.3 0.1 0.026 13.7 0.0 2.0 2 0 0 2 2 2 1 PAXNEB protein LpxC PF03331.13 CBK22933.2 - 0.081 12.4 0.0 0.15 11.6 0.0 1.4 1 0 0 1 1 1 0 UDP-3-O-acyl N-acetylglycosamine deacetylase AAA PF00004.29 CBK22933.2 - 0.13 12.7 0.0 0.76 10.2 0.0 2.2 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) SopD PF11047.8 CBK22934.2 - 0.22 10.7 0.1 0.22 10.7 0.1 1.7 2 0 0 2 2 2 0 Salmonella outer protein D Rad51 PF08423.11 CBK22936.2 - 2.4e-121 403.8 0.0 3.4e-121 403.3 0.0 1.2 1 0 0 1 1 1 1 Rad51 RecA PF00154.21 CBK22936.2 - 3.5e-12 46.3 0.1 5.4e-12 45.7 0.1 1.3 1 0 0 1 1 1 1 recA bacterial DNA recombination protein AAA_25 PF13481.6 CBK22936.2 - 1.8e-08 34.2 0.0 2.8e-08 33.6 0.0 1.2 1 0 0 1 1 1 1 AAA domain ATPase PF06745.13 CBK22936.2 - 3.8e-06 26.4 0.0 7.9e-06 25.4 0.0 1.6 1 1 0 1 1 1 1 KaiC DnaB_C PF03796.15 CBK22936.2 - 3.3e-05 23.3 0.0 0.0038 16.6 0.0 2.3 2 0 0 2 2 2 2 DnaB-like helicase C terminal domain HHH_5 PF14520.6 CBK22936.2 - 5e-05 23.8 1.0 0.00011 22.7 1.0 1.5 1 0 0 1 1 1 1 Helix-hairpin-helix domain AAA_24 PF13479.6 CBK22936.2 - 0.00021 21.1 0.0 0.0004 20.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain PAXNEB PF05625.11 CBK22936.2 - 0.0041 16.3 0.1 0.026 13.7 0.0 2.0 2 0 0 2 2 2 1 PAXNEB protein LpxC PF03331.13 CBK22936.2 - 0.081 12.4 0.0 0.15 11.6 0.0 1.4 1 0 0 1 1 1 0 UDP-3-O-acyl N-acetylglycosamine deacetylase AAA PF00004.29 CBK22936.2 - 0.13 12.7 0.0 0.76 10.2 0.0 2.2 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Pkinase PF00069.25 CBK22938.2 - 1.4e-71 240.9 0.0 1.8e-71 240.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBK22938.2 - 6.1e-28 97.8 0.0 7.8e-28 97.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 CBK22938.2 - 6.8e-05 22.0 0.0 0.00041 19.4 0.0 2.0 1 1 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 CBK22938.2 - 0.004 16.5 0.0 0.1 11.9 0.0 2.2 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 CBK22938.2 - 0.005 16.8 0.0 0.0073 16.3 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family RabGAP-TBC PF00566.18 CBK22939.2 - 1.1e-08 35.0 0.1 1.2e-08 34.9 0.1 1.0 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Ras PF00071.22 CBK22940.2 - 9.7e-26 90.3 0.0 1.1e-25 90.1 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CBK22940.2 - 8.3e-12 45.4 0.0 9.1e-12 45.2 0.0 1.1 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CBK22940.2 - 0.0011 18.4 0.0 0.0012 18.4 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family vATP-synt_E PF01991.18 CBK22941.2 - 2.4e-49 167.4 5.1 3e-49 167.2 5.1 1.1 1 0 0 1 1 1 1 ATP synthase (E/31 kDa) subunit Folliculin PF11704.8 CBK22941.2 - 2.2 8.2 5.4 2.8 7.8 5.4 1.2 1 0 0 1 1 1 0 Vesicle coat protein involved in Golgi to plasma membrane transport YtxH PF12732.7 CBK22941.2 - 3.8 8.1 5.2 35 5.0 5.2 2.2 1 1 0 1 1 1 0 YtxH-like protein P16-Arc PF04699.14 CBK22942.2 - 2.5e-09 37.8 0.0 2.6e-09 37.7 0.0 1.1 1 0 0 1 1 1 1 ARP2/3 complex 16 kDa subunit (p16-Arc) Utp12 PF04003.12 CBK22942.2 - 0.008 16.5 0.0 0.014 15.7 0.0 1.5 2 0 0 2 2 2 1 Dip2/Utp12 Family RNA_helicase PF00910.22 CBK22943.2 - 7.2e-09 36.0 0.1 1.6e-08 34.9 0.1 1.6 1 0 0 1 1 1 1 RNA helicase AAA_16 PF13191.6 CBK22943.2 - 0.036 14.4 0.0 0.07 13.5 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain ATPase_2 PF01637.18 CBK22943.2 - 0.13 12.2 0.0 0.68 9.8 0.0 2.1 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea AAA_24 PF13479.6 CBK22943.2 - 0.17 11.6 0.0 0.32 10.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain Yae1_N PF09811.9 CBK22945.2 - 0.0041 16.8 4.4 0.0066 16.1 4.4 1.3 1 0 0 1 1 1 1 Essential protein Yae1, N terminal GBP PF02263.19 CBK22946.2 - 7.6e-23 81.1 0.0 8.7e-23 80.9 0.0 1.0 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain SfLAP PF11139.8 CBK22947.2 - 1.2 8.5 9.9 0.23 10.9 1.5 2.3 1 1 1 2 2 2 0 Sap, sulfolipid-1-addressing protein CNDH2_C PF16858.5 CBK22948.2 - 4e-39 135.2 0.4 4.5e-39 135.1 0.4 1.0 1 0 0 1 1 1 1 Condensin II complex subunit CAP-H2 or CNDH2, C-term CRA PF06589.11 CBK22948.2 - 0.03 14.4 1.0 0.036 14.2 1.0 1.2 1 0 0 1 1 1 0 Circumsporozoite-related antigen (CRA) Ribosomal_L4 PF00573.22 CBK22949.2 - 1.7e-39 135.5 0.1 3.2e-39 134.6 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Ribos_L4_asso_C PF14374.6 CBK22949.2 - 1e-22 80.0 1.6 4.2e-22 78.0 1.5 2.1 2 0 0 2 2 2 1 60S ribosomal protein L4 C-terminal domain Ribonuc_P_40 PF08584.11 CBK22949.2 - 0.051 12.8 0.0 0.11 11.8 0.0 1.4 1 0 0 1 1 1 0 Ribonuclease P 40kDa (Rpp40) subunit Ribosomal_L2_C PF03947.18 CBK22950.2 - 1.4e-45 154.6 1.6 2.1e-45 154.0 1.6 1.2 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 CBK22950.2 - 1.2e-14 54.0 0.1 3.4e-14 52.6 0.0 1.9 2 0 0 2 2 2 1 Ribosomal Proteins L2, RNA binding domain RIO1 PF01163.22 CBK22951.2 - 1.8e-47 161.3 0.1 1.8e-47 161.3 0.1 2.5 2 1 0 2 2 2 1 RIO1 family Rio2_N PF09202.11 CBK22951.2 - 7.9e-24 83.7 0.2 7.9e-24 83.7 0.2 2.1 3 0 0 3 3 3 1 Rio2, N-terminal APH PF01636.23 CBK22951.2 - 1.8e-09 37.9 0.3 0.0006 19.8 0.1 2.5 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 CBK22951.2 - 8.7e-05 22.0 0.1 0.0038 16.6 0.0 3.0 4 0 0 4 4 4 2 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 CBK22951.2 - 0.82 9.2 0.0 0.82 9.2 0.0 2.6 2 1 0 2 2 2 0 Choline/ethanolamine kinase PIRT PF15099.6 CBK22952.2 - 0.00029 20.4 2.1 0.0003 20.4 2.1 1.0 1 0 0 1 1 1 1 Phosphoinositide-interacting protein family DUF3169 PF11368.8 CBK22952.2 - 0.0062 16.1 2.7 0.0073 15.8 2.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3169) DUF5455 PF17537.2 CBK22952.2 - 0.0089 16.4 2.0 0.011 16.1 2.0 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF5455) SUR7 PF06687.12 CBK22952.2 - 0.012 15.2 2.6 0.014 15.1 2.6 1.1 1 0 0 1 1 1 0 SUR7/PalI family MARVEL PF01284.23 CBK22952.2 - 0.013 15.5 0.9 0.014 15.4 0.9 1.1 1 0 0 1 1 1 0 Membrane-associating domain DUF2070 PF09843.9 CBK22952.2 - 0.017 13.5 4.9 0.018 13.4 4.9 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) DUF2569 PF10754.9 CBK22952.2 - 0.022 15.2 4.7 0.024 15.1 4.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2569) AgrB PF04647.15 CBK22952.2 - 0.022 14.0 5.7 0.019 14.3 4.6 1.4 1 1 0 1 1 1 0 Accessory gene regulator B DUF1129 PF06570.11 CBK22952.2 - 0.033 13.7 1.3 0.033 13.7 1.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) DUF2663 PF10864.8 CBK22952.2 - 0.041 14.3 1.7 0.048 14.1 1.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2663) CoA_binding_3 PF13727.6 CBK22952.2 - 0.049 13.6 1.7 0.054 13.5 1.7 1.1 1 0 0 1 1 1 0 CoA-binding domain DUF267 PF03268.14 CBK22952.2 - 0.051 12.4 5.2 0.057 12.3 5.2 1.1 1 0 0 1 1 1 0 Caenorhabditis protein of unknown function, DUF267 DUF2207 PF09972.9 CBK22952.2 - 0.073 11.8 1.3 0.085 11.6 1.3 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) TMEM208_SND2 PF05620.11 CBK22952.2 - 0.13 12.1 1.6 0.14 11.9 1.6 1.2 1 0 0 1 1 1 0 SRP-independent targeting protein 2/TMEM208 TMEM100 PF16311.5 CBK22952.2 - 0.22 11.1 1.0 0.24 11.0 1.0 1.1 1 0 0 1 1 1 0 Transmembrane protein 100 AC_N PF16214.5 CBK22952.2 - 0.38 9.8 2.8 0.38 9.8 2.8 1.0 1 0 0 1 1 1 0 Adenylyl cyclase N-terminal extracellular and transmembrane region TMEM132D_C PF15706.5 CBK22952.2 - 0.66 9.8 3.1 0.38 10.6 0.7 1.7 1 1 1 2 2 2 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term PfkB PF00294.24 CBK22953.2 - 2.5e-29 102.6 0.0 2e-28 99.6 0.0 2.0 2 0 0 2 2 2 1 pfkB family carbohydrate kinase SIS PF01380.22 CBK22953.2 - 5.1e-18 65.2 0.0 8.7e-18 64.4 0.0 1.3 1 0 0 1 1 1 1 SIS domain SIS_2 PF13580.6 CBK22953.2 - 2e-06 27.9 0.1 0.00089 19.3 0.0 2.4 1 1 1 2 2 2 2 SIS domain PAF-AH_p_II PF03403.13 CBK22953.2 - 0.052 12.1 0.0 0.078 11.5 0.0 1.2 1 0 0 1 1 1 0 Platelet-activating factor acetylhydrolase, isoform II DUF563 PF04577.14 CBK22954.2 - 1.9e-21 77.2 0.1 2.4e-21 76.8 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF563) Pkinase PF00069.25 CBK22955.2 - 8.7e-37 126.9 0.0 9.7e-37 126.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBK22955.2 - 8.4e-21 74.4 0.0 2.2e-20 73.0 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.22 CBK22955.2 - 0.071 12.7 0.2 0.11 12.1 0.2 1.2 1 0 0 1 1 1 0 RIO1 family DNA_topoisoIV PF00521.20 CBK22955.2 - 0.11 11.3 0.0 0.16 10.9 0.0 1.1 1 0 0 1 1 1 0 DNA gyrase/topoisomerase IV, subunit A Peptidase_S9_N PF02897.15 CBK22956.2 - 3.3e-21 75.6 1.0 5.5e-21 74.9 0.4 1.7 2 0 0 2 2 2 1 Prolyl oligopeptidase, N-terminal beta-propeller domain Peptidase_S9 PF00326.21 CBK22956.2 - 1.2e-18 67.4 0.0 2.5e-18 66.3 0.0 1.5 2 0 0 2 2 2 1 Prolyl oligopeptidase family HSP70 PF00012.20 CBK22957.2 - 9.3e-62 209.1 0.0 1.1e-61 208.8 0.0 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 CBK22957.2 - 2.5e-10 39.7 0.0 5.9e-10 38.5 0.0 1.6 1 0 0 1 1 1 1 MreB/Mbl protein Fe-ADH PF00465.19 CBK22958.2 - 1.5e-74 251.0 0.0 1.9e-74 250.7 0.0 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.6 CBK22958.2 - 5.5e-05 23.0 0.1 0.0012 18.6 0.0 2.2 2 0 0 2 2 2 1 Iron-containing alcohol dehydrogenase CbiK PF06180.11 CBK22958.2 - 0.025 13.9 0.1 0.063 12.6 0.0 1.6 2 0 0 2 2 2 0 Cobalt chelatase (CbiK) HGTP_anticodon PF03129.20 CBK22959.2 - 3.1e-18 65.7 1.4 7.4e-18 64.5 0.0 2.4 3 0 0 3 3 3 1 Anticodon binding domain WHEP-TRS PF00458.20 CBK22959.2 - 3.4e-09 36.7 8.9 7e-09 35.7 8.9 1.5 1 0 0 1 1 1 1 WHEP-TRS domain tRNA-synt_2b PF00587.25 CBK22959.2 - 5.3e-09 36.3 0.0 4.4e-08 33.3 0.0 2.5 2 1 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) IL31 PF15209.6 CBK22959.2 - 0.16 11.7 0.1 0.35 10.6 0.1 1.5 1 0 0 1 1 1 0 Interleukin 31 Phage_holin_7_1 PF16081.5 CBK22959.2 - 0.19 11.9 0.4 0.49 10.6 0.4 1.6 1 0 0 1 1 1 0 Mycobacterial 2 TMS Phage Holin (M2 Hol) Family RNR_Alpha PF17975.1 CBK22960.2 - 2.4e-40 137.1 0.1 5.2e-40 136.0 0.1 1.6 1 0 0 1 1 1 1 Ribonucleotide reductase alpha domain Ribonuc_red_lgC PF02867.15 CBK22960.2 - 2.3e-10 39.6 0.0 0.0018 16.9 0.0 3.2 3 0 0 3 3 3 3 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.21 CBK22960.2 - 0.00024 21.1 0.0 0.00056 19.9 0.0 1.7 1 0 0 1 1 1 1 Ribonucleotide reductase, all-alpha domain TIM PF00121.18 CBK22961.2 - 9.5e-88 293.7 0.1 1.1e-87 293.5 0.1 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase IGPS PF00218.21 CBK22961.2 - 0.0073 15.5 0.1 0.013 14.7 0.1 1.3 1 1 0 1 1 1 1 Indole-3-glycerol phosphate synthase YfkD PF14167.6 CBK22961.2 - 0.044 13.0 0.0 0.071 12.3 0.0 1.3 1 0 0 1 1 1 0 YfkD-like protein E3_UFM1_ligase PF09743.9 CBK22961.2 - 0.067 12.8 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 E3 UFM1-protein ligase 1 WD40 PF00400.32 CBK22962.2 - 1.3e-43 146.1 32.4 6.4e-08 33.1 0.0 12.7 13 1 1 14 14 14 9 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBK22962.2 - 1.5e-14 54.1 3.5 1.9e-05 24.8 0.0 7.1 5 2 1 7 7 7 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 CBK22962.2 - 8e-05 21.5 2.1 0.53 8.9 0.0 5.3 6 1 1 7 7 7 2 Nucleoporin Nup120/160 eIF2A PF08662.11 CBK22962.2 - 8.3e-05 22.5 0.1 0.029 14.2 0.0 3.6 3 1 1 4 4 4 1 Eukaryotic translation initiation factor eIF2A HPS3_N PF14761.6 CBK22962.2 - 0.00033 20.3 0.2 6.6 6.2 0.0 4.8 4 1 1 5 5 5 2 Hermansky-Pudlak syndrome 3 WD40_like PF17005.5 CBK22962.2 - 0.0037 16.6 6.7 2.3 7.5 0.2 4.7 4 2 0 4 4 4 2 WD40-like domain U3_assoc_6 PF08640.11 CBK22963.2 - 4.2e-27 94.0 2.7 2.7e-26 91.4 0.7 2.4 2 0 0 2 2 2 1 U3 small nucleolar RNA-associated protein 6 NRDE-2 PF08424.10 CBK22963.2 - 0.0003 20.0 0.3 0.0042 16.3 0.0 2.1 1 1 1 2 2 2 2 NRDE-2, necessary for RNA interference Suf PF05843.14 CBK22963.2 - 0.0013 18.8 0.0 0.011 15.7 0.0 2.1 1 1 0 1 1 1 1 Suppressor of forked protein (Suf) TPR_14 PF13428.6 CBK22963.2 - 0.031 15.1 0.1 19 6.4 0.0 3.1 1 1 2 3 3 3 0 Tetratricopeptide repeat TPR_MalT PF17874.1 CBK22964.2 - 0.061 12.7 1.2 0.086 12.2 0.8 1.4 1 1 0 1 1 1 0 MalT-like TPR region zf-C2H2 PF00096.26 CBK22965.2 - 2.4e-25 87.5 41.5 6.5e-06 26.3 1.2 6.6 6 0 0 6 6 6 6 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CBK22965.2 - 3e-19 68.1 40.0 0.0008 20.0 1.1 6.6 6 0 0 6 6 6 6 C2H2-type zinc finger zf-H2C2_2 PF13465.6 CBK22965.2 - 1.1e-13 50.9 37.1 0.0045 17.4 1.9 7.4 7 0 0 7 7 7 4 Zinc-finger double domain zf-C2H2_6 PF13912.6 CBK22965.2 - 1e-08 35.0 31.8 6.2e-05 22.9 0.5 6.6 7 0 0 7 7 7 4 C2H2-type zinc finger zf-met PF12874.7 CBK22965.2 - 0.0002 21.6 26.2 0.25 11.8 0.8 6.4 6 0 0 6 6 6 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 CBK22965.2 - 0.00032 20.9 26.9 0.0057 16.9 0.4 6.6 6 0 0 6 6 6 2 Zinc-finger double-stranded RNA-binding zf_UBZ PF18439.1 CBK22965.2 - 0.0048 16.5 7.5 0.62 9.7 0.2 4.2 4 0 0 4 4 4 2 Ubiquitin-Binding Zinc Finger PhnA_Zn_Ribbon PF08274.12 CBK22965.2 - 0.053 13.5 0.4 4.7 7.3 0.0 3.4 3 0 0 3 3 3 0 PhnA Zinc-Ribbon zf-C2H2_2 PF12756.7 CBK22965.2 - 0.14 12.5 23.4 0.17 12.2 0.1 4.5 1 1 4 5 5 5 0 C2H2 type zinc-finger (2 copies) DUF555 PF04475.12 CBK22965.2 - 0.16 12.3 0.0 0.45 10.9 0.0 1.7 2 0 0 2 2 1 0 Protein of unknown function (DUF555) zf-Di19 PF05605.12 CBK22965.2 - 0.21 11.9 26.8 0.071 13.4 4.2 4.3 1 1 4 5 5 5 0 Drought induced 19 protein (Di19), zinc-binding DUF4428 PF14471.6 CBK22965.2 - 0.25 11.3 5.7 5.2 7.1 0.4 4.0 3 1 0 3 3 3 0 Domain of unknown function (DUF4428) Zn-C2H2_12 PF18112.1 CBK22965.2 - 0.35 11.4 0.2 0.35 11.4 0.2 4.4 4 0 0 4 4 4 0 Autophagy receptor zinc finger-C2H2 domain zf-RING_10 PF16685.5 CBK22965.2 - 2.7 8.2 10.8 2.5 8.3 1.1 3.2 2 1 1 3 3 3 0 zinc RING finger of MSL2 zf-DNA_Pol PF08996.10 CBK22965.2 - 3.7 7.3 11.7 4.5 7.0 3.8 2.3 2 0 0 2 2 2 0 DNA Polymerase alpha zinc finger zf-C3HC4_3 PF13920.6 CBK22965.2 - 4.2 7.3 15.3 0.37 10.7 0.5 4.1 4 0 0 4 4 4 0 Zinc finger, C3HC4 type (RING finger) C1_4 PF07975.12 CBK22965.2 - 4.8 7.5 22.0 2.1 8.7 2.9 4.0 3 1 1 4 4 4 0 TFIIH C1-like domain zf-C2H2_8 PF15909.5 CBK22965.2 - 5.4 7.4 23.5 2.9 8.3 2.7 3.2 2 1 1 3 3 3 0 C2H2-type zinc ribbon zf-MYST PF17772.1 CBK22965.2 - 6.5 6.4 16.3 1.5 8.5 1.0 4.2 3 2 0 3 3 3 0 MYST family zinc finger domain AAA PF00004.29 CBK22966.2 - 1.5e-98 326.3 0.0 6.6e-48 162.5 0.0 2.3 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CBK22966.2 - 1.4e-28 98.4 7.4 1.4e-15 56.8 0.3 3.5 3 0 0 3 3 3 2 AAA+ lid domain CDC48_N PF02359.18 CBK22966.2 - 8.9e-17 61.0 1.0 2.6e-16 59.6 1.0 1.8 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain RuvB_N PF05496.12 CBK22966.2 - 4e-15 55.9 0.0 8.6e-07 28.8 0.0 2.9 2 2 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 CBK22966.2 - 1e-13 51.8 0.0 1.2e-06 28.7 0.0 2.6 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 CBK22966.2 - 1.9e-12 47.9 0.0 0.00017 22.0 0.0 4.1 2 2 0 2 2 2 2 AAA ATPase domain AAA_33 PF13671.6 CBK22966.2 - 5.7e-11 42.8 0.0 1.8e-05 25.0 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.14 CBK22966.2 - 7.9e-11 42.1 0.1 2.7e-05 24.2 0.0 3.6 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 CBK22966.2 - 8e-10 39.1 0.3 0.0085 16.4 0.1 3.8 2 2 1 3 3 3 2 AAA domain AAA_14 PF13173.6 CBK22966.2 - 2.4e-08 34.1 0.0 0.00079 19.5 0.0 2.6 2 0 0 2 2 2 2 AAA domain TIP49 PF06068.13 CBK22966.2 - 6.6e-08 32.1 0.0 0.0011 18.2 0.0 2.5 2 0 0 2 2 2 2 TIP49 P-loop domain Vps4_C PF09336.10 CBK22966.2 - 9.2e-08 32.0 0.2 4.4e-06 26.6 0.0 2.7 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain CDC48_2 PF02933.17 CBK22966.2 - 1.1e-07 31.5 0.0 1.5e-06 27.8 0.0 2.4 2 0 0 2 2 2 1 Cell division protein 48 (CDC48), domain 2 AAA_18 PF13238.6 CBK22966.2 - 1.8e-07 31.7 0.0 0.028 15.0 0.0 2.9 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.22 CBK22966.2 - 3.1e-07 30.8 0.0 0.011 16.1 0.0 3.1 2 1 0 2 2 2 2 RNA helicase Mg_chelatase PF01078.21 CBK22966.2 - 9.9e-07 28.3 0.5 0.054 12.9 0.0 2.9 4 0 0 4 4 2 2 Magnesium chelatase, subunit ChlI ATPase_2 PF01637.18 CBK22966.2 - 1.7e-06 28.1 0.1 0.021 14.7 0.0 3.0 3 1 0 3 3 2 2 ATPase domain predominantly from Archaea IstB_IS21 PF01695.17 CBK22966.2 - 4.6e-06 26.5 0.1 0.19 11.4 0.0 3.1 2 1 1 3 3 3 2 IstB-like ATP binding protein ABC_tran PF00005.27 CBK22966.2 - 1.6e-05 25.4 0.0 0.95 10.0 0.0 4.1 3 1 0 3 3 3 2 ABC transporter AAA_17 PF13207.6 CBK22966.2 - 1.8e-05 25.1 0.0 0.13 12.7 0.0 3.2 3 0 0 3 3 2 2 AAA domain UFD1 PF03152.14 CBK22966.2 - 2.3e-05 24.0 0.0 4.4e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 Sigma54_activat PF00158.26 CBK22966.2 - 2.7e-05 23.9 0.0 0.3 10.8 0.0 3.8 2 2 1 3 3 3 1 Sigma-54 interaction domain Bac_DnaA PF00308.18 CBK22966.2 - 3.3e-05 23.8 0.0 0.04 13.8 0.0 2.5 2 0 0 2 2 2 1 Bacterial dnaA protein Viral_helicase1 PF01443.18 CBK22966.2 - 3.6e-05 23.6 0.0 0.01 15.6 0.0 2.5 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase AAA_7 PF12775.7 CBK22966.2 - 5.1e-05 22.9 0.0 0.12 11.9 0.0 2.6 2 1 0 2 2 2 2 P-loop containing dynein motor region AAA_24 PF13479.6 CBK22966.2 - 5.8e-05 22.9 0.0 0.058 13.1 0.0 2.7 2 1 0 2 2 2 1 AAA domain NACHT PF05729.12 CBK22966.2 - 6.4e-05 22.9 0.0 0.4 10.6 0.0 3.4 3 1 1 4 4 3 2 NACHT domain AAA_25 PF13481.6 CBK22966.2 - 7.6e-05 22.4 0.3 2.7 7.5 0.1 3.5 2 1 1 3 3 3 1 AAA domain TsaE PF02367.17 CBK22966.2 - 0.0001 22.3 0.0 0.42 10.6 0.0 2.5 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE Molydop_binding PF01568.21 CBK22966.2 - 0.00011 22.2 0.0 0.00027 20.9 0.0 1.6 1 0 0 1 1 1 1 Molydopterin dinucleotide binding domain AAA_28 PF13521.6 CBK22966.2 - 0.00011 22.5 0.0 0.61 10.3 0.0 2.5 2 0 0 2 2 2 2 AAA domain Zeta_toxin PF06414.12 CBK22966.2 - 0.00016 21.0 0.1 0.74 9.1 0.0 2.8 3 0 0 3 3 2 2 Zeta toxin ATPase PF06745.13 CBK22966.2 - 0.00016 21.1 0.4 1 8.7 0.0 3.6 3 1 0 4 4 3 2 KaiC Parvo_NS1 PF01057.17 CBK22966.2 - 0.00033 19.9 0.0 0.38 9.8 0.0 2.3 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 DUF815 PF05673.13 CBK22966.2 - 0.0004 19.6 0.0 0.28 10.3 0.0 2.5 2 1 0 2 2 2 1 Protein of unknown function (DUF815) NB-ARC PF00931.22 CBK22966.2 - 0.0004 19.7 0.0 0.93 8.6 0.0 2.4 2 0 0 2 2 2 2 NB-ARC domain Rad17 PF03215.15 CBK22966.2 - 0.00045 20.2 0.0 0.078 12.9 0.0 2.4 2 0 0 2 2 2 1 Rad17 P-loop domain Sigma54_activ_2 PF14532.6 CBK22966.2 - 0.00047 20.3 0.0 1.5 8.9 0.0 3.1 2 1 1 3 3 3 1 Sigma-54 interaction domain NTPase_1 PF03266.15 CBK22966.2 - 0.00047 20.1 0.5 3.4 7.5 0.0 4.6 4 1 1 5 5 4 1 NTPase ResIII PF04851.15 CBK22966.2 - 0.00057 19.9 0.0 0.14 12.2 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_3 PF07726.11 CBK22966.2 - 0.0013 18.6 0.0 1.7 8.5 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 CBK22966.2 - 0.0027 17.2 0.1 2.8 7.3 0.1 2.6 2 0 0 2 2 2 1 PhoH-like protein Cytidylate_kin2 PF13189.6 CBK22966.2 - 0.005 17.0 0.0 0.83 9.8 0.0 2.4 2 0 0 2 2 2 1 Cytidylate kinase-like family DUF2075 PF09848.9 CBK22966.2 - 0.013 14.7 0.0 1.6 7.9 0.0 2.4 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_11 PF13086.6 CBK22966.2 - 0.015 15.1 0.0 6 6.6 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 CBK22966.2 - 0.026 14.2 0.0 8.4 6.1 0.1 2.4 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.6 CBK22966.2 - 0.042 14.2 0.8 15 5.9 0.1 3.4 3 1 1 4 4 3 0 AAA domain Zot PF05707.12 CBK22966.2 - 0.048 13.3 0.0 1.1 8.9 0.0 2.5 2 0 0 2 2 2 0 Zonular occludens toxin (Zot) AAA_29 PF13555.6 CBK22966.2 - 0.12 12.2 0.0 6.5 6.6 0.0 2.7 2 0 0 2 2 2 0 P-loop containing region of AAA domain KAP_NTPase PF07693.14 CBK22966.2 - 0.17 11.1 0.2 13 4.9 0.0 3.1 2 2 1 3 3 3 0 KAP family P-loop domain Pro_isomerase PF00160.21 CBK22967.2 - 3.2e-50 170.5 0.2 4.4e-50 170.0 0.2 1.2 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Ribosomal_L30 PF00327.20 CBK22968.2 - 1.1e-20 73.3 1.8 2.5e-20 72.1 1.8 1.7 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e Ribosomal_L30_N PF08079.12 CBK22968.2 - 2.3e-09 37.4 10.0 5.2e-09 36.2 10.0 1.6 1 0 0 1 1 1 1 Ribosomal L30 N-terminal domain BEX PF04538.12 CBK22968.2 - 0.24 12.0 2.3 0.43 11.2 2.3 1.3 1 0 0 1 1 1 0 Brain expressed X-linked like family Nucleoporin2 PF04096.14 CBK22970.2 - 2.4e-20 73.1 0.0 3.8e-20 72.5 0.0 1.2 1 0 0 1 1 1 1 Nucleoporin autopeptidase HSP20 PF00011.21 CBK22971.2 - 2.4e-17 62.9 0.0 3.5e-17 62.4 0.0 1.2 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 CBK22971.2 - 7.9e-05 22.1 0.0 0.00015 21.3 0.0 1.5 1 0 0 1 1 1 1 HSP20-like domain found in ArsA Amidohydro_1 PF01979.20 CBK22972.2 - 3.4e-15 56.2 0.0 4.1e-15 55.9 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 CBK22972.2 - 0.27 10.7 0.2 0.43 10.0 0.2 1.2 1 0 0 1 1 1 0 Amidohydrolase family Amidohydro_1 PF01979.20 CBK22973.2 - 1.2e-42 146.5 3.0 1.4e-42 146.3 3.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 CBK22973.2 - 3e-16 59.9 0.0 3.8e-16 59.6 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family A_deaminase PF00962.22 CBK22973.2 - 0.014 14.8 0.0 0.019 14.3 0.0 1.2 1 0 0 1 1 1 0 Adenosine/AMP deaminase Vps54_N PF10475.9 CBK22974.2 - 0.012 14.9 0.1 0.042 13.1 0.0 1.9 2 0 0 2 2 2 0 Vacuolar-sorting protein 54, of GARP complex Vps54 PF07928.12 CBK22975.2 - 7.6e-31 107.3 6.5 1.2e-30 106.7 1.6 2.4 2 0 0 2 2 2 1 Vps54-like protein DUF1485 PF07364.12 CBK22975.2 - 0.0084 15.4 0.1 0.069 12.4 0.0 2.1 1 1 1 2 2 2 1 Metallopeptidase family M81 Trypan_PARP PF05887.11 CBK22977.2 - 0.017 15.1 10.1 0.017 15.1 10.1 1.5 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) LRR_8 PF13855.6 CBK22977.2 - 0.028 14.2 5.6 8.3 6.3 0.1 4.3 4 1 1 5 5 5 0 Leucine rich repeat DNA_pol_B_2 PF03175.13 CBK22978.2 - 1.6e-18 66.9 10.6 5.1e-17 61.9 10.6 2.4 1 1 0 1 1 1 1 DNA polymerase type B, organellar and viral PDZ_1 PF12812.7 CBK22978.2 - 0.15 12.1 0.0 43 4.2 0.0 3.5 3 0 0 3 3 3 0 PDZ-like domain Trypan_PARP PF05887.11 CBK22979.2 - 8.5e-05 22.5 12.7 0.00013 21.9 12.7 1.2 1 0 0 1 1 1 1 Procyclic acidic repetitive protein (PARP) LRR_8 PF13855.6 CBK22979.2 - 0.00023 20.8 3.8 0.84 9.4 0.0 4.3 3 1 1 4 4 4 2 Leucine rich repeat hSac2 PF12456.8 CBK22979.2 - 0.0018 18.0 0.3 0.035 13.8 0.0 2.9 1 1 2 3 3 3 1 Inositol phosphatase Sialidase PF02973.16 CBK22979.2 - 0.12 11.8 0.0 1 8.8 0.0 2.5 2 1 1 3 3 3 0 Sialidase, N-terminal domain GBP PF02263.19 CBK22980.2 - 2.3e-36 125.4 0.0 3.1e-36 125.0 0.0 1.1 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain MFS_1 PF07690.16 CBK22981.2 - 3.3e-44 151.3 20.5 9e-33 113.6 11.3 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 CBK22981.2 - 1.2e-11 44.2 24.7 2e-11 43.4 24.6 1.5 1 1 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.13 CBK22981.2 - 1.1e-06 27.4 3.5 1.1e-06 27.4 3.5 1.6 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) NUC153 PF08159.12 CBK22982.2 - 7e-11 41.8 0.3 1.4e-10 40.8 0.3 1.6 1 0 0 1 1 1 1 NUC153 domain ANAPC4_WD40 PF12894.7 CBK22982.2 - 7.9e-06 26.1 0.0 0.011 16.0 0.0 2.5 1 1 1 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain SAPS PF04499.15 CBK22982.2 - 7.9 5.1 16.4 12 4.6 16.4 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein BCDHK_Adom3 PF10436.9 CBK22983.2 - 1.2e-40 139.1 0.0 1.9e-40 138.4 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 CBK22983.2 - 2.2e-10 41.0 0.0 4.8e-10 39.9 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 CBK22983.2 - 0.0029 17.4 0.0 0.0053 16.6 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Chitin_synth_2 PF03142.15 CBK22985.2 - 9.1e-28 97.2 1.0 2.5e-25 89.1 0.3 2.3 2 0 0 2 2 2 2 Chitin synthase Chitin_synth_1 PF01644.17 CBK22985.2 - 4.4e-27 95.0 0.0 1.1e-26 93.8 0.0 1.7 1 1 0 1 1 1 1 Chitin synthase Glyco_trans_2_3 PF13632.6 CBK22985.2 - 4.4e-13 49.6 0.2 1e-12 48.4 0.2 1.7 1 0 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 CBK22985.2 - 2e-06 27.9 0.0 3.8e-06 27.0 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_49 PF13896.6 CBK22986.2 - 2.5e-15 56.7 0.2 1e-09 38.3 0.0 2.5 1 1 1 2 2 2 2 Glycosyl-transferase for dystroglycan VPS13_C PF16909.5 CBK22987.2 - 1.7e-41 142.0 0.9 2.1e-35 122.1 0.0 2.2 2 0 0 2 2 2 2 Vacuolar-sorting-associated 13 protein C-terminal ATG_C PF09333.11 CBK22987.2 - 0.028 14.8 0.0 0.078 13.3 0.0 1.7 2 0 0 2 2 2 0 Autophagy-related protein C terminal domain Chorein_N PF12624.7 CBK22989.2 - 1.1e-36 125.4 0.7 5.1e-36 123.3 0.7 2.3 1 0 0 1 1 1 1 N-terminal region of Chorein or VPS13 VPS13 PF16908.5 CBK22989.2 - 6.7e-31 107.9 11.2 2.8e-19 69.9 0.1 4.1 4 1 0 4 4 4 2 Vacuolar sorting-associated protein 13, N-terminal VPS13_mid_rpt PF16910.5 CBK22989.2 - 5.4e-19 68.6 3.6 3.6e-17 62.6 0.0 4.1 3 1 0 3 3 3 1 Repeating coiled region of VPS13 zf-HIT PF04438.16 CBK22993.2 - 1.9e-11 43.6 9.4 1.9e-11 43.6 9.4 1.5 2 0 0 2 2 2 1 HIT zinc finger zf-MYND PF01753.18 CBK22993.2 - 0.034 14.2 11.9 0.08 13.1 12.1 1.6 1 1 0 1 1 1 0 MYND finger PolC_DP2 PF03833.13 CBK22993.2 - 5.7 4.7 7.0 5.9 4.6 7.0 1.0 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 MCM PF00493.23 CBK22994.2 - 3.7e-94 314.0 0.0 7.2e-94 313.1 0.0 1.5 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 CBK22994.2 - 4.6e-35 120.2 0.1 8.1e-35 119.4 0.1 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 CBK22994.2 - 4.1e-25 88.0 0.1 1.2e-24 86.5 0.1 1.8 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 CBK22994.2 - 2e-15 57.3 0.4 5.6e-15 55.8 0.4 1.7 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 CBK22994.2 - 5.8e-08 32.4 0.0 2.6e-06 27.0 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 CBK22994.2 - 4.6e-05 23.4 0.0 0.00011 22.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.26 CBK22994.2 - 0.0073 16.0 0.0 0.24 11.1 0.0 2.4 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_3 PF07726.11 CBK22994.2 - 0.013 15.4 0.0 0.11 12.4 0.0 2.3 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) 6PGD PF00393.19 CBK22995.2 - 4e-30 105.2 0.0 5.9e-30 104.6 0.0 1.1 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.15 CBK22995.2 - 8.5e-25 87.8 0.0 1.3e-24 87.1 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase IlvN PF07991.12 CBK22995.2 - 0.0048 16.5 0.0 0.0094 15.5 0.0 1.4 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain zf-primase PF09329.11 CBK22996.2 - 9.7e-14 50.9 2.2 4.5e-13 48.8 0.7 2.4 2 0 0 2 2 2 1 Primase zinc finger Lar_restr_allev PF14354.6 CBK22996.2 - 0.036 14.4 1.4 6 7.3 0.0 3.1 2 0 0 2 2 2 0 Restriction alleviation protein Lar tRNA_anti-codon PF01336.25 CBK22996.2 - 0.043 13.8 0.0 0.088 12.8 0.0 1.6 1 0 0 1 1 1 0 OB-fold nucleic acid binding domain Mcm10 PF09332.11 CBK22996.2 - 0.11 11.9 28.2 0.068 12.6 22.9 2.0 1 1 1 2 2 2 0 Mcm10 replication factor HSP70 PF00012.20 CBK22997.2 - 1.2e-85 288.0 0.6 1.5e-85 287.6 0.6 1.1 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 CBK22997.2 - 4.8e-11 42.0 0.6 1.6e-07 30.5 0.2 3.1 2 1 0 2 2 2 1 MreB/Mbl protein StbA PF06406.11 CBK22997.2 - 4e-05 23.0 0.5 0.12 11.6 0.2 2.4 1 1 0 2 2 2 2 StbA protein DDR PF08841.10 CBK22997.2 - 0.0022 17.0 0.0 1.2 8.1 0.0 2.3 2 0 0 2 2 2 2 Diol dehydratase reactivase ATPase-like domain TFB6 PF17110.5 CBK22997.2 - 0.01 15.6 1.1 0.019 14.7 1.1 1.4 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH BcrAD_BadFG PF01869.20 CBK22997.2 - 0.021 14.3 0.1 1.7 8.1 0.0 2.3 2 0 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family DUF3069 PF11269.8 CBK22997.2 - 0.029 14.6 2.2 0.076 13.3 2.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3069) FtsA PF14450.6 CBK22997.2 - 0.15 12.5 2.9 26 5.3 0.0 3.4 3 1 0 3 3 3 0 Cell division protein FtsA Myc_N PF01056.18 CBK22997.2 - 1.8 8.4 5.9 0.88 9.4 3.2 1.7 2 0 0 2 2 2 0 Myc amino-terminal region HATPase_c_3 PF13589.6 CBK22998.2 - 2.4e-06 27.4 0.3 8e-06 25.7 0.3 1.8 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 CBK22998.2 - 0.0017 18.9 0.2 0.0036 17.8 0.1 1.7 2 1 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DNA_mis_repair PF01119.19 CBK22999.2 - 7.1e-12 45.0 0.1 8.2e-12 44.8 0.1 1.0 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain MutL_C PF08676.11 CBK23000.2 - 1.2e-33 116.0 0.1 1.5e-33 115.6 0.1 1.2 1 0 0 1 1 1 1 MutL C terminal dimerisation domain Spec3 PF15795.5 CBK23001.2 - 4.6e-07 30.3 18.9 1.9e-05 25.1 18.9 2.2 1 1 0 1 1 1 1 Ectodermal ciliogenesis protein DUF3464 PF11947.8 CBK23001.2 - 0.0033 17.2 0.1 0.029 14.1 0.0 2.0 2 0 0 2 2 2 1 Photosynthesis affected mutant 68 VIT1 PF01988.19 CBK23001.2 - 0.14 12.0 0.0 0.27 11.0 0.0 1.4 1 1 0 1 1 1 0 VIT family Aa_trans PF01490.18 CBK23002.2 - 2.7e-12 46.1 9.7 3e-12 46.0 9.7 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein KbaA PF14089.6 CBK23002.2 - 0.033 14.0 0.9 0.033 14.0 0.9 2.0 1 1 0 2 2 2 0 KinB-signalling pathway activation in sporulation DUF1772 PF08592.11 CBK23002.2 - 1.5 9.1 4.6 5.3 7.4 4.6 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF1772) Aa_trans PF01490.18 CBK23003.2 - 8.5e-38 130.1 24.1 1.4e-36 126.1 24.1 1.9 1 1 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 CBK23003.2 - 4.8e-05 22.6 7.1 8.1e-05 21.8 7.1 1.5 1 0 0 1 1 1 1 Tryptophan/tyrosine permease family RWD PF05773.22 CBK23004.2 - 5.7e-13 49.2 2.1 9.3e-13 48.5 2.1 1.3 1 0 0 1 1 1 1 RWD domain FNIP_M PF14637.6 CBK23004.2 - 0.053 13.5 0.1 0.066 13.2 0.1 1.1 1 0 0 1 1 1 0 Folliculin-interacting protein middle domain HC2 PF07382.11 CBK23005.2 - 1.1e-23 84.3 63.6 5.9e-07 29.8 4.7 5.1 5 0 0 5 5 5 5 Histone H1-like nucleoprotein HC2 ASFV_J13L PF05568.11 CBK23005.2 - 0.00041 20.2 22.6 0.019 14.8 0.9 5.5 6 0 0 6 6 6 3 African swine fever virus J13L protein Lsm_interact PF05391.11 CBK23005.2 - 1.5 8.4 14.3 55 3.5 0.3 5.9 4 0 0 4 4 4 0 Lsm interaction motif Glyco_hydro_47 PF01532.20 CBK23006.2 - 9.1e-84 282.0 0.0 1.1e-83 281.6 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Pkinase PF00069.25 CBK23007.2 - 7.9e-07 28.7 0.0 9.1e-07 28.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase PF00069.25 CBK23008.2 - 9.9e-45 152.9 0.0 1.1e-44 152.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBK23008.2 - 6.3e-23 81.4 0.0 7e-23 81.2 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CBK23008.2 - 2.6e-06 27.0 0.0 8.3e-05 22.0 0.0 2.3 2 1 1 3 3 3 1 Kinase-like Imm7 PF15585.6 CBK23008.2 - 0.024 14.9 0.0 0.1 12.9 0.0 1.9 2 0 0 2 2 2 0 Immunity protein 7 CDC4_D PF16856.5 CBK23008.2 - 0.041 13.7 0.0 0.079 12.8 0.0 1.5 1 0 0 1 1 1 0 Cell division control protein 4 dimerisation domain APH PF01636.23 CBK23008.2 - 0.11 12.5 0.2 0.99 9.3 0.0 2.1 1 1 0 2 2 2 0 Phosphotransferase enzyme family HSP70 PF00012.20 CBK23009.2 - 2.2e-182 607.4 1.2 2.4e-87 293.5 0.0 4.1 4 0 0 4 4 4 4 Hsp70 protein MreB_Mbl PF06723.13 CBK23009.2 - 1.5e-26 93.0 0.1 1.3e-09 37.3 0.0 4.8 3 2 0 4 4 4 4 MreB/Mbl protein DDR PF08841.10 CBK23009.2 - 7e-09 35.1 1.5 0.0025 16.9 0.0 4.5 5 0 0 5 5 5 2 Diol dehydratase reactivase ATPase-like domain Hydantoinase_A PF01968.18 CBK23009.2 - 5.6e-05 22.5 0.4 0.13 11.5 0.0 2.6 2 0 0 2 2 2 2 Hydantoinase/oxoprolinase StbA PF06406.11 CBK23009.2 - 0.0082 15.4 1.6 3.9 6.6 0.0 3.2 3 2 0 3 3 3 2 StbA protein DUF3999 PF13163.6 CBK23009.2 - 0.044 13.0 0.3 7.2 5.7 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3999) MOZ_SAS PF01853.18 CBK23009.2 - 0.061 13.0 0.6 9.2 5.9 0.1 2.4 2 0 0 2 2 2 0 MOZ/SAS family HEPN_LA2681 PF18733.1 CBK23009.2 - 0.19 11.0 3.3 7.5 5.8 0.3 2.3 2 0 0 2 2 2 0 LA2681-like HEPN UCH_C PF18031.1 CBK23009.2 - 4.3 7.3 5.3 5.2 7.1 0.3 2.6 2 0 0 2 2 2 0 Ubiquitin carboxyl-terminal hydrolases RecA PF00154.21 CBK23010.2 - 1.7e-136 453.8 0.3 2.2e-136 453.5 0.3 1.1 1 0 0 1 1 1 1 recA bacterial DNA recombination protein Rad51 PF08423.11 CBK23010.2 - 1.5e-11 44.1 0.2 1.5e-10 40.8 0.2 2.0 1 1 0 1 1 1 1 Rad51 ATPase PF06745.13 CBK23010.2 - 2.8e-06 26.8 0.3 3.3e-05 23.3 0.3 2.4 1 1 0 1 1 1 1 KaiC ATPase_2 PF01637.18 CBK23010.2 - 7.5e-05 22.8 0.0 0.00021 21.3 0.0 1.7 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea AAA_24 PF13479.6 CBK23010.2 - 0.00018 21.3 0.0 0.00033 20.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.6 CBK23010.2 - 0.0011 18.6 0.6 0.025 14.1 0.6 2.2 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 CBK23010.2 - 0.0051 17.2 0.2 0.017 15.5 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain ABC_tran PF00005.27 CBK23010.2 - 0.0074 16.8 0.0 0.023 15.2 0.0 2.0 1 1 0 1 1 1 1 ABC transporter CobU PF02283.16 CBK23010.2 - 0.032 13.8 0.0 0.057 13.0 0.0 1.4 1 0 0 1 1 1 0 Cobinamide kinase / cobinamide phosphate guanyltransferase AAA PF00004.29 CBK23010.2 - 0.049 14.1 0.0 0.1 13.0 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) MobB PF03205.14 CBK23010.2 - 0.12 12.3 0.1 0.3 11.0 0.0 1.7 1 1 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B DFP PF04127.15 CBK23010.2 - 0.14 12.0 0.0 8.8 6.1 0.0 2.9 2 1 1 3 3 3 0 DNA / pantothenate metabolism flavoprotein DnaJ PF00226.31 CBK23011.2 - 1.6e-22 79.4 0.2 2.2e-22 78.9 0.2 1.2 1 0 0 1 1 1 1 DnaJ domain zf-CSL PF05207.13 CBK23011.2 - 1.1e-11 44.3 8.1 1.7e-11 43.7 8.1 1.3 1 0 0 1 1 1 1 CSL zinc finger zinc_ribbon_4 PF13717.6 CBK23011.2 - 0.0037 17.1 1.1 0.0077 16.1 1.1 1.5 1 0 0 1 1 1 1 zinc-ribbon domain Spectrin PF00435.21 CBK23011.2 - 0.092 13.2 0.0 0.15 12.6 0.0 1.3 1 0 0 1 1 1 0 Spectrin repeat Enolase_C PF00113.22 CBK23011.2 - 0.13 11.5 0.0 0.13 11.4 0.0 1.1 1 0 0 1 1 1 0 Enolase, C-terminal TIM barrel domain Macoilin PF09726.9 CBK23012.2 - 2.3 6.7 13.2 2.4 6.6 13.2 1.1 1 0 0 1 1 1 0 Macoilin family Hamartin PF04388.12 CBK23012.2 - 2.6 6.6 13.9 3 6.4 13.9 1.0 1 0 0 1 1 1 0 Hamartin protein Homeobox_KN PF05920.11 CBK23013.2 - 4.4e-16 58.5 3.1 4.4e-16 58.5 3.1 2.1 2 0 0 2 2 2 1 Homeobox KN domain Homeodomain PF00046.29 CBK23013.2 - 2.4e-08 33.7 4.6 2.4e-08 33.7 4.6 2.3 2 0 0 2 2 2 1 Homeodomain Invasin_D3 PF09134.10 CBK23013.2 - 0.042 14.2 0.0 0.086 13.2 0.0 1.5 1 0 0 1 1 1 0 Invasin, domain 3 MT-A70 PF05063.14 CBK23014.2 - 3.9e-34 118.0 0.0 6.4e-34 117.3 0.0 1.4 1 0 0 1 1 1 1 MT-A70 PHD PF00628.29 CBK23014.2 - 5.7e-08 32.5 8.5 1e-07 31.7 8.5 1.4 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 CBK23014.2 - 0.00042 19.8 4.9 0.00081 18.9 4.9 1.5 1 0 0 1 1 1 1 PHD-finger zf-Sec23_Sec24 PF04810.15 CBK23014.2 - 0.00088 19.3 2.0 0.0018 18.3 2.0 1.6 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger COX5B PF01215.19 CBK23014.2 - 0.22 11.2 0.9 0.44 10.2 0.4 1.7 2 0 0 2 2 2 0 Cytochrome c oxidase subunit Vb Ras PF00071.22 CBK23015.2 - 2e-41 141.3 0.2 2.4e-41 141.1 0.2 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CBK23015.2 - 1.7e-19 70.2 0.1 2.8e-19 69.5 0.1 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CBK23015.2 - 1.6e-10 40.7 0.1 2e-10 40.4 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 CBK23015.2 - 0.0019 17.7 0.0 0.0053 16.3 0.0 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Thoc2 PF11732.8 CBK23015.2 - 0.078 13.0 0.0 0.15 12.2 0.0 1.4 1 0 0 1 1 1 0 Transcription- and export-related complex subunit Ras PF00071.22 CBK23016.2 - 3.9e-09 36.3 0.0 4.4e-09 36.1 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CBK23016.2 - 6.5e-08 32.8 0.0 7.4e-08 32.6 0.0 1.1 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CBK23016.2 - 1.4e-05 24.7 0.0 1.4e-05 24.6 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family TniB PF05621.11 CBK23016.2 - 0.00083 18.8 0.0 0.00083 18.8 0.0 1.0 1 0 0 1 1 1 1 Bacterial TniB protein MMR_HSR1 PF01926.23 CBK23016.2 - 0.011 15.8 0.0 0.012 15.7 0.0 1.1 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_29 PF13555.6 CBK23016.2 - 0.031 14.0 0.0 0.038 13.7 0.0 1.2 1 0 0 1 1 1 0 P-loop containing region of AAA domain MCM PF00493.23 CBK23016.2 - 0.042 12.9 0.0 0.042 12.9 0.0 1.0 1 0 0 1 1 1 0 MCM P-loop domain AAA_24 PF13479.6 CBK23016.2 - 0.098 12.4 0.0 0.098 12.4 0.0 1.1 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 CBK23016.2 - 0.098 12.2 0.0 0.1 12.1 0.0 1.1 1 0 0 1 1 1 0 P-loop containing dynein motor region VirE PF05272.11 CBK23016.2 - 0.21 11.3 0.0 0.22 11.2 0.0 1.0 1 0 0 1 1 1 0 Virulence-associated protein E Glyco_transf_5 PF08323.11 CBK23017.2 - 2.3e-30 106.1 0.0 4.3e-30 105.2 0.0 1.4 1 0 0 1 1 1 1 Starch synthase catalytic domain Glycos_transf_1 PF00534.20 CBK23017.2 - 3.9e-12 46.1 0.0 9.4e-12 44.8 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 CBK23017.2 - 5.6e-10 39.8 0.0 1e-08 35.7 0.0 2.6 2 1 0 2 2 2 1 Glycosyl transferases group 1 AMPK1_CBM PF16561.5 CBK23017.2 - 6.1e-08 32.8 0.0 1.5e-07 31.5 0.0 1.6 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase Glyco_transf_4 PF13439.6 CBK23017.2 - 0.00033 20.7 0.0 0.0013 18.8 0.0 2.0 1 1 0 1 1 1 1 Glycosyltransferase Family 4 CBM_48 PF02922.18 CBK23017.2 - 0.0025 18.1 0.0 0.0074 16.6 0.0 1.8 1 0 0 1 1 1 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) Glyco_trans_4_4 PF13579.6 CBK23017.2 - 0.1 13.0 0.0 0.29 11.6 0.0 1.7 1 1 0 1 1 1 0 Glycosyl transferase 4-like domain AMPK1_CBM PF16561.5 CBK23018.2 - 6.3e-07 29.5 0.0 1.1e-06 28.7 0.0 1.3 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase CBM_48 PF02922.18 CBK23018.2 - 0.00067 20.0 0.3 0.0027 18.0 0.0 2.0 1 1 1 2 2 2 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) CBM53 PF16760.5 CBK23018.2 - 0.025 15.2 0.0 0.066 13.8 0.0 1.7 1 1 0 1 1 1 0 Starch/carbohydrate-binding module (family 53) Alpha-amylase PF00128.24 CBK23019.2 - 0.066 12.8 0.0 0.097 12.2 0.0 1.2 1 0 0 1 1 1 0 Alpha amylase, catalytic domain UPF0016 PF01169.19 CBK23021.2 - 3.5e-35 120.2 20.6 4.3e-19 68.6 4.9 2.6 2 0 0 2 2 2 2 Uncharacterized protein family UPF0016 TerC PF03741.16 CBK23021.2 - 0.01 15.5 7.0 0.013 15.2 4.2 2.2 2 0 0 2 2 2 0 Integral membrane protein TerC family Mntp PF02659.15 CBK23021.2 - 0.015 15.1 9.6 0.099 12.4 0.5 2.6 2 0 0 2 2 2 0 Putative manganese efflux pump Ashwin PF15323.6 CBK23021.2 - 1.2 9.1 6.5 2.8 7.9 6.5 1.6 1 0 0 1 1 1 0 Developmental protein LRR_4 PF12799.7 CBK23022.2 - 1.9e-09 37.7 6.3 0.3 11.6 0.1 6.9 6 2 0 6 6 6 3 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 CBK23022.2 - 0.092 12.9 15.5 3.3 8.0 0.0 8.5 12 0 0 12 12 12 0 Leucine Rich repeat LRR_8 PF13855.6 CBK23022.2 - 0.63 9.8 14.7 36 4.2 1.6 7.4 6 2 0 6 6 6 0 Leucine rich repeat PhoLip_ATPase_C PF16212.5 CBK23023.2 - 2e-32 112.9 21.6 2e-32 112.9 21.6 2.1 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 CBK23023.2 - 1.8e-19 69.2 2.1 1.8e-19 69.2 2.1 2.9 3 0 0 3 3 3 1 Phospholipid-translocating ATPase N-terminal E1-E2_ATPase PF00122.20 CBK23023.2 - 2.4e-12 46.7 0.4 2.8e-09 36.8 0.1 3.8 3 1 0 3 3 3 1 E1-E2 ATPase Cation_ATPase PF13246.6 CBK23023.2 - 9.5e-09 35.2 0.0 2.6e-08 33.9 0.0 1.7 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 CBK23023.2 - 1.7e-08 35.0 0.0 0.0044 17.3 0.0 3.5 3 0 0 3 3 3 3 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 CBK23023.2 - 0.0098 15.6 0.1 0.024 14.4 0.1 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase tRNA-synt_2d PF01409.20 CBK23024.2 - 1.8e-47 161.9 0.0 3.3e-47 161.1 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) FDX-ACB PF03147.14 CBK23024.2 - 7e-23 80.9 1.5 2.7e-22 79.0 0.1 2.5 3 0 0 3 3 3 1 Ferredoxin-fold anticodon binding domain tRNA-synt_2 PF00152.20 CBK23024.2 - 0.0027 16.8 0.0 0.64 9.1 0.1 2.3 2 0 0 2 2 2 2 tRNA synthetases class II (D, K and N) LRR_8 PF13855.6 CBK23025.2 - 0.0025 17.5 1.5 0.28 11.0 0.3 3.6 3 0 0 3 3 3 1 Leucine rich repeat TAXi_C PF14541.6 CBK23026.2 - 3.1e-18 66.1 0.0 4.8e-18 65.4 0.0 1.3 1 0 0 1 1 1 1 Xylanase inhibitor C-terminal Asp PF00026.23 CBK23026.2 - 0.0005 19.6 0.0 0.0023 17.4 0.0 2.3 2 1 0 2 2 2 1 Eukaryotic aspartyl protease RNR_Alpha PF17975.1 CBK23027.2 - 2.8e-40 136.9 0.1 6.1e-40 135.8 0.1 1.6 1 0 0 1 1 1 1 Ribonucleotide reductase alpha domain Ribonuc_red_lgC PF02867.15 CBK23027.2 - 3.3e-10 39.1 0.0 0.0024 16.5 0.0 3.2 3 0 0 3 3 3 3 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.21 CBK23027.2 - 0.00033 20.6 0.0 0.00075 19.5 0.0 1.6 1 0 0 1 1 1 1 Ribonucleotide reductase, all-alpha domain DAGK_cat PF00781.24 CBK23028.2 - 1.5e-19 69.9 0.0 2.5e-19 69.1 0.0 1.4 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain DUF4296 PF14129.6 CBK23028.2 - 0.016 15.8 0.4 0.033 14.8 0.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4296) CLAMP PF14769.6 CBK23028.2 - 0.12 12.8 0.9 3.8 8.0 0.1 2.6 2 0 0 2 2 2 0 Flagellar C1a complex subunit C1a-32 ThiF PF00899.21 CBK23029.2 - 1.9e-46 158.4 5.1 2.4e-43 148.2 2.1 3.3 2 1 0 2 2 2 1 ThiF family Sod_Fe_C PF02777.18 CBK23029.2 - 1.3e-36 124.9 0.3 1.3e-36 124.9 0.3 1.9 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, C-terminal domain THF_DHG_CYH_C PF02882.19 CBK23029.2 - 2.5e-30 104.9 0.4 2.5e-30 104.9 0.4 3.0 3 1 0 3 3 3 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Sod_Fe_N PF00081.22 CBK23029.2 - 4.5e-29 100.7 0.3 8.6e-29 99.9 0.3 1.5 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain Sacchrp_dh_NADP PF03435.18 CBK23029.2 - 1.9e-06 28.2 0.0 1.5e-05 25.3 0.0 2.2 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_7 PF13241.6 CBK23029.2 - 0.0028 18.1 0.0 0.0089 16.5 0.0 1.8 2 0 0 2 2 2 1 Putative NAD(P)-binding Shikimate_DH PF01488.20 CBK23029.2 - 0.005 16.9 0.0 0.022 14.8 0.0 2.1 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase UL41A PF17591.2 CBK23029.2 - 0.041 14.0 0.1 0.099 12.7 0.1 1.6 1 0 0 1 1 1 0 Herpesvirus UL41A AlaDh_PNT_C PF01262.21 CBK23029.2 - 0.25 10.6 0.7 3.7 6.8 0.0 2.9 3 1 0 3 3 3 0 Alanine dehydrogenase/PNT, C-terminal domain THF_DHG_CYH PF00763.23 CBK23030.2 - 2.3e-24 85.9 0.0 2.6e-24 85.7 0.0 1.0 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain Ribosomal_S27e PF01667.17 CBK23031.2 - 1.7e-24 85.3 3.3 1.7e-24 85.3 3.3 1.8 2 0 0 2 2 2 1 Ribosomal protein S27 IBR PF01485.21 CBK23031.2 - 0.018 15.2 2.7 0.033 14.4 2.7 1.5 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain zf-NADH-PPase PF09297.11 CBK23031.2 - 0.07 12.8 0.7 0.18 11.5 0.0 2.0 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain TF_Zn_Ribbon PF08271.12 CBK23031.2 - 0.1 12.1 3.5 0.22 11.1 3.5 1.5 1 0 0 1 1 1 0 TFIIB zinc-binding HGTP_anticodon PF03129.20 CBK23032.2 - 3.2e-18 65.7 1.3 7.5e-18 64.5 0.0 2.3 3 0 0 3 3 3 1 Anticodon binding domain tRNA-synt_2b PF00587.25 CBK23032.2 - 5.1e-09 36.3 0.0 4.5e-08 33.3 0.0 2.5 2 1 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) WHEP-TRS PF00458.20 CBK23032.2 - 1.6e-06 28.2 5.8 3.3e-06 27.1 5.8 1.5 1 0 0 1 1 1 1 WHEP-TRS domain IL31 PF15209.6 CBK23032.2 - 0.12 12.1 0.1 0.27 11.0 0.1 1.5 1 0 0 1 1 1 0 Interleukin 31 Phage_holin_7_1 PF16081.5 CBK23032.2 - 0.16 12.1 0.1 0.41 10.8 0.1 1.6 1 0 0 1 1 1 0 Mycobacterial 2 TMS Phage Holin (M2 Hol) Family Steroid_dh PF02544.16 CBK23033.2 - 3e-29 101.9 4.0 5.6e-29 101.1 4.0 1.5 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1295 PF06966.12 CBK23033.2 - 0.0015 18.1 0.7 0.0021 17.6 0.7 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF1295) Ubiquitin_2 PF14560.6 CBK23033.2 - 0.02 15.3 0.3 0.037 14.5 0.3 1.5 1 0 0 1 1 1 0 Ubiquitin-like domain ubiquitin PF00240.23 CBK23033.2 - 0.085 12.6 0.6 0.24 11.2 0.6 1.7 1 1 0 1 1 1 0 Ubiquitin family PEMT PF04191.13 CBK23033.2 - 0.22 11.9 0.3 0.22 11.9 0.3 2.3 1 1 0 2 2 2 0 Phospholipid methyltransferase UPF0004 PF00919.20 CBK23034.2 - 1.9e-21 75.9 0.1 3.6e-21 75.0 0.1 1.5 1 0 0 1 1 1 1 Uncharacterized protein family UPF0004 Radical_SAM PF04055.21 CBK23034.2 - 9.5e-18 65.1 0.0 2.3e-17 63.9 0.0 1.7 2 0 0 2 2 2 1 Radical SAM superfamily Sugar_tr PF00083.24 CBK23035.2 - 2e-49 168.7 36.6 2.1e-35 122.4 24.5 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 CBK23035.2 - 9.1e-12 44.6 59.3 8.4e-11 41.4 29.6 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2370 PF10176.9 CBK23035.2 - 0.065 12.9 0.1 0.065 12.9 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2370) DUF1129 PF06570.11 CBK23035.2 - 0.87 9.0 12.5 0.5 9.8 9.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1129) Lig_chan PF00060.26 CBK23035.2 - 8.5 6.2 9.2 3.5 7.5 4.1 2.7 2 1 0 2 2 2 0 Ligand-gated ion channel BPL_LplA_LipB PF03099.19 CBK23036.2 - 5.9e-21 74.7 0.0 1e-20 74.0 0.0 1.4 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family eIF2A PF08662.11 CBK23037.2 - 4.1e-35 121.4 0.0 2.9e-33 115.4 0.0 2.9 2 1 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A ANAPC4_WD40 PF12894.7 CBK23037.2 - 1.7e-05 25.0 0.1 1.4 9.3 0.0 5.5 2 2 4 6 6 6 1 Anaphase-promoting complex subunit 4 WD40 domain Coatomer_WDAD PF04053.14 CBK23037.2 - 0.0027 16.8 0.0 0.94 8.4 0.0 3.0 1 1 2 3 3 3 2 Coatomer WD associated region Cwf_Cwc_15 PF04889.12 CBK23037.2 - 0.0044 16.8 1.0 0.007 16.1 1.0 1.2 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein WD40 PF00400.32 CBK23037.2 - 0.044 14.7 5.9 1 10.4 0.1 4.9 6 0 0 6 6 6 0 WD domain, G-beta repeat GST_C_2 PF13410.6 CBK23037.2 - 0.28 11.2 1.9 3.5 7.7 0.1 3.2 4 0 0 4 4 4 0 Glutathione S-transferase, C-terminal domain TFIIIC_delta PF12657.7 CBK23037.2 - 0.41 10.6 3.7 46 3.9 0.5 4.5 3 2 1 4 4 4 0 Transcription factor IIIC subunit delta N-term DNA_pol_B PF00136.21 CBK23038.2 - 1.2e-141 472.6 0.1 1.6e-141 472.2 0.1 1.1 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 CBK23038.2 - 1.2e-53 182.4 0.5 2.1e-53 181.6 0.1 1.6 2 0 0 2 2 2 1 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.6 CBK23038.2 - 1.3e-14 54.4 14.2 3e-14 53.2 14.2 1.7 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta DNA_pol_B_2 PF03175.13 CBK23038.2 - 5.6e-05 22.2 0.4 0.00017 20.6 0.2 1.8 2 0 0 2 2 2 1 DNA polymerase type B, organellar and viral RNase_H_2 PF13482.6 CBK23038.2 - 0.0049 16.9 0.4 0.076 13.0 0.4 2.4 1 1 0 1 1 1 1 RNase_H superfamily 2-oxoacid_dh PF00198.23 CBK23039.2 - 1.1e-69 234.5 0.2 1.4e-69 234.1 0.2 1.1 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 CBK23039.2 - 1.3e-17 63.4 0.3 3.2e-17 62.1 0.3 1.7 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.17 CBK23039.2 - 5.6e-10 39.4 0.2 1.5e-09 38.0 0.1 1.8 2 0 0 2 2 2 1 e3 binding domain Biotin_lipoyl_2 PF13533.6 CBK23039.2 - 5.5e-07 29.3 0.0 2.8e-06 27.1 0.0 2.2 1 1 1 2 2 2 1 Biotin-lipoyl like HlyD_3 PF13437.6 CBK23039.2 - 0.0089 16.7 0.1 0.037 14.7 0.0 2.1 1 1 1 2 2 2 1 HlyD family secretion protein PYNP_C PF07831.13 CBK23039.2 - 0.062 13.0 0.0 6.4 6.5 0.0 2.3 2 0 0 2 2 2 0 Pyrimidine nucleoside phosphorylase C-terminal domain CCDC53 PF10152.9 CBK23039.2 - 0.24 11.8 3.8 0.64 10.4 3.8 1.8 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex DUF1631 PF07793.11 CBK23039.2 - 4.9 5.5 10.4 6.3 5.1 10.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1631) WD40 PF00400.32 CBK23040.2 - 3.1e-36 122.8 21.2 2.8e-08 34.3 0.6 7.4 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.8 CBK23040.2 - 0.053 12.2 1.7 11 4.6 0.0 3.8 2 1 2 4 4 4 0 Nucleoporin Nup120/160 GH97_C PF14509.6 CBK23040.2 - 1.1 9.6 2.9 0.98 9.7 0.1 2.4 3 0 0 3 3 3 0 Glycosyl-hydrolase 97 C-terminal, oligomerisation Mito_carr PF00153.27 CBK23041.2 - 6.9e-19 67.6 0.1 6.5e-11 42.0 0.1 2.3 2 0 0 2 2 2 2 Mitochondrial carrier protein Ribosomal_L10 PF00466.20 CBK23042.2 - 1.5e-20 73.2 0.7 3.3e-20 72.1 0.2 1.7 2 1 0 2 2 2 1 Ribosomal protein L10 RL10P_insert PF17777.1 CBK23042.2 - 2.1e-18 66.0 0.1 1.1e-17 63.8 0.1 2.0 2 0 0 2 2 2 1 Insertion domain in 60S ribosomal protein L10P Ribosomal_60s PF00428.19 CBK23042.2 - 1.1e-12 48.4 7.4 2.5e-12 47.2 7.4 1.7 1 0 0 1 1 1 1 60s Acidic ribosomal protein VirE_N PF08800.10 CBK23042.2 - 0.18 12.0 0.0 0.3 11.2 0.0 1.3 1 0 0 1 1 1 0 VirE N-terminal domain DIE2_ALG10 PF04922.12 CBK23044.2 - 1.8e-72 244.8 29.6 3.5e-72 243.9 29.6 1.5 1 0 0 1 1 1 1 DIE2/ALG10 family ABC_tran PF00005.27 CBK23044.2 - 2.5e-30 105.8 0.0 4.5e-30 104.9 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 CBK23044.2 - 5e-07 29.8 0.8 0.018 14.9 0.0 2.5 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 CBK23044.2 - 0.0001 21.8 0.6 0.23 10.8 0.0 2.3 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_30 PF13604.6 CBK23044.2 - 0.0019 18.0 0.0 0.0076 16.0 0.0 1.8 1 1 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 CBK23044.2 - 0.002 18.1 0.1 0.0053 16.7 0.1 1.6 1 0 0 1 1 1 1 RsgA GTPase AAA_29 PF13555.6 CBK23044.2 - 0.0028 17.4 0.1 0.0064 16.2 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.6 CBK23044.2 - 0.026 14.9 0.1 0.05 14.0 0.1 1.5 1 1 0 1 1 1 0 AAA ATPase domain MMR_HSR1 PF01926.23 CBK23044.2 - 0.058 13.5 0.1 0.12 12.5 0.1 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_23 PF13476.6 CBK23044.2 - 0.13 12.8 0.1 0.3 11.6 0.1 1.5 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 CBK23044.2 - 0.22 11.7 0.0 0.47 10.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain Nucleoporin_FG PF13634.6 CBK23045.2 - 2.2e-26 92.5 266.0 6e-08 33.4 52.5 5.5 1 1 5 6 6 6 6 Nucleoporin FG repeat region XRN_M PF17846.1 CBK23045.2 - 8.1 5.3 23.4 13 4.5 23.4 1.5 1 0 0 1 1 1 0 Xrn1 helical domain PI3_PI4_kinase PF00454.27 CBK23046.2 - 1.6e-40 139.5 2.5 2.7e-27 96.2 0.2 2.1 1 1 1 2 2 2 2 Phosphatidylinositol 3- and 4-kinase FYVE PF01363.21 CBK23046.2 - 0.0003 20.9 3.3 0.00064 19.8 3.3 1.7 1 0 0 1 1 1 1 FYVE zinc finger DUF4135 PF13575.6 CBK23046.2 - 0.001 18.5 0.0 0.0015 17.9 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4135) Met_gamma_lyase PF06838.11 CBK23046.2 - 0.097 11.2 0.0 0.11 11.0 0.0 1.2 1 0 0 1 1 1 0 Methionine gamma-lyase tRNA-Thr_ED PF08915.11 CBK23046.2 - 0.14 12.2 0.0 0.22 11.6 0.0 1.3 1 0 0 1 1 1 0 Archaea-specific editing domain of threonyl-tRNA synthetase FYVE_2 PF02318.16 CBK23046.2 - 1.7 8.9 9.4 1.9 8.7 7.1 2.1 1 1 1 2 2 2 0 FYVE-type zinc finger PI3Ka PF00613.20 CBK23047.2 - 1.1e-20 73.9 0.0 1.7e-20 73.2 0.0 1.3 1 1 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) Trypan_PARP PF05887.11 CBK23047.2 - 2.2 8.3 23.0 15 5.6 23.0 2.0 1 1 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) COPI_assoc PF08507.10 CBK23048.2 - 1.2e-11 44.8 6.1 1.8e-11 44.2 6.1 1.3 1 0 0 1 1 1 1 COPI associated protein DUF5589 PF17672.1 CBK23048.2 - 0.31 11.0 1.7 0.83 9.6 1.7 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5589) TMEM43 PF07787.12 CBK23048.2 - 0.4 10.0 1.5 0.7 9.2 1.5 1.4 1 0 0 1 1 1 0 Transmembrane protein 43 DUF563 PF04577.14 CBK23049.2 - 4.1e-23 82.6 1.0 1.1e-22 81.2 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF563) SesA PF17107.5 CBK23049.2 - 0.27 11.4 2.0 0.36 11.0 0.5 1.9 2 0 0 2 2 2 0 N-terminal domain on NACHT_NTPase and P-loop NTPases RRM_1 PF00076.22 CBK23052.2 - 1.3e-05 24.9 0.0 5.5e-05 22.9 0.0 2.0 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) YceG PF02618.16 CBK23052.2 - 0.009 15.6 0.4 0.015 14.9 0.4 1.3 1 0 0 1 1 1 1 YceG-like family CNDH2_C PF16858.5 CBK23052.2 - 1.4 8.7 18.6 7.9 6.3 0.0 2.2 1 1 1 2 2 2 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term Peptidase_S8 PF00082.22 CBK23053.2 - 1.9e-26 93.1 1.8 2.3e-25 89.5 0.2 2.3 2 0 0 2 2 2 2 Subtilase family NIF PF03031.18 CBK23054.2 - 2.2e-39 134.7 0.2 2.7e-39 134.5 0.2 1.1 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase TPR_1 PF00515.28 CBK23055.2 - 1.6e-26 91.0 19.5 9.2e-05 22.1 0.0 9.7 10 0 0 10 10 10 6 Tetratricopeptide repeat TPR_2 PF07719.17 CBK23055.2 - 2.3e-26 89.7 25.1 0.00018 21.3 0.0 11.2 12 0 0 12 12 11 6 Tetratricopeptide repeat TPR_8 PF13181.6 CBK23055.2 - 5.7e-23 79.2 25.3 0.0012 18.9 0.1 11.2 11 0 0 11 11 11 5 Tetratricopeptide repeat TPR_12 PF13424.6 CBK23055.2 - 3.8e-18 65.6 21.8 3.1e-05 24.2 0.0 8.7 6 2 1 8 8 8 5 Tetratricopeptide repeat TPR_17 PF13431.6 CBK23055.2 - 1.1e-17 63.1 7.9 0.00033 20.8 0.1 9.1 10 0 0 10 10 10 4 Tetratricopeptide repeat TPR_16 PF13432.6 CBK23055.2 - 2.5e-16 60.0 25.0 2e-07 31.5 0.0 7.4 5 4 4 9 9 8 3 Tetratricopeptide repeat TPR_19 PF14559.6 CBK23055.2 - 2.1e-15 57.0 13.2 0.00076 19.9 0.1 6.8 2 2 6 8 8 8 4 Tetratricopeptide repeat TPR_14 PF13428.6 CBK23055.2 - 4.8e-13 48.7 21.9 0.0016 19.1 0.0 9.9 3 2 8 11 11 11 2 Tetratricopeptide repeat TPR_9 PF13371.6 CBK23055.2 - 2.8e-12 46.6 8.5 0.00092 19.3 0.2 6.1 4 2 2 6 6 6 3 Tetratricopeptide repeat TPR_11 PF13414.6 CBK23055.2 - 2.3e-11 43.2 5.5 0.007 16.0 0.1 7.1 4 2 4 8 8 8 2 TPR repeat NARP1 PF12569.8 CBK23055.2 - 4.6e-11 42.3 7.7 0.027 13.4 0.5 5.9 3 3 4 7 7 7 4 NMDA receptor-regulated protein 1 TPR_6 PF13174.6 CBK23055.2 - 1.8e-07 31.3 34.4 0.019 15.6 0.0 10.9 12 0 0 12 12 12 2 Tetratricopeptide repeat ANAPC3 PF12895.7 CBK23055.2 - 4e-07 30.2 12.5 0.033 14.4 0.4 4.8 3 2 2 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_5 PF12688.7 CBK23055.2 - 1.5e-06 28.5 2.6 0.0061 16.8 0.2 3.0 3 0 0 3 3 3 2 Tetratrico peptide repeat DUF3808 PF10300.9 CBK23055.2 - 5.6e-06 25.4 15.8 0.0019 17.1 0.2 4.1 2 1 2 4 4 4 2 Protein of unknown function (DUF3808) HTH_Bact PF18768.1 CBK23055.2 - 0.00012 21.6 0.4 0.0047 16.5 0.2 3.1 2 0 0 2 2 2 1 Helix-turn-helix bacterial domain TPR_7 PF13176.6 CBK23055.2 - 0.00054 19.8 18.1 0.018 15.1 0.0 8.0 9 0 0 9 9 8 1 Tetratricopeptide repeat Suf PF05843.14 CBK23055.2 - 0.0024 17.9 2.3 0.18 11.8 0.2 2.4 2 0 0 2 2 2 1 Suppressor of forked protein (Suf) ChAPs PF09295.10 CBK23055.2 - 0.015 14.3 1.2 3 6.8 0.0 3.4 3 1 1 4 4 4 0 ChAPs (Chs5p-Arf1p-binding proteins) PknG_TPR PF16918.5 CBK23055.2 - 0.018 13.8 0.8 0.093 11.4 0.1 2.3 3 0 0 3 3 3 0 Protein kinase G tetratricopeptide repeat MIT PF04212.18 CBK23055.2 - 0.032 14.3 11.5 0.16 12.1 1.5 5.2 4 2 0 4 4 2 0 MIT (microtubule interacting and transport) domain TPR_4 PF07721.14 CBK23055.2 - 0.038 14.6 0.4 42 5.2 0.0 4.7 4 0 0 4 4 3 0 Tetratricopeptide repeat Vps5 PF09325.10 CBK23055.2 - 0.16 11.5 5.8 0.34 10.4 0.7 3.1 3 0 0 3 3 3 0 Vps5 C terminal like TPR_10 PF13374.6 CBK23055.2 - 0.84 9.6 0.0 0.84 9.6 0.0 8.2 10 0 0 10 10 10 0 Tetratricopeptide repeat Alkyl_sulf_dimr PF14863.6 CBK23055.2 - 1.9 9.0 5.3 0.73 10.3 0.1 2.8 3 0 0 3 3 3 0 Alkyl sulfatase dimerisation PRKCSH_1 PF13015.6 CBK23056.2 - 8.5e-05 22.3 0.9 0.00092 18.9 0.9 2.1 1 1 0 1 1 1 1 Glucosidase II beta subunit-like protein PRKCSH PF07915.13 CBK23056.2 - 0.00085 20.3 1.4 0.00085 20.3 1.4 2.1 2 0 0 2 2 2 1 Glucosidase II beta subunit-like protein EF_TS PF00889.19 CBK23059.2 - 1e-52 178.8 0.1 1.6e-52 178.2 0.1 1.3 1 0 0 1 1 1 1 Elongation factor TS DUF4332 PF14229.6 CBK23059.2 - 0.062 13.5 0.7 0.11 12.8 0.2 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4332) UBA PF00627.31 CBK23059.2 - 0.18 11.8 0.0 0.42 10.6 0.0 1.7 1 0 0 1 1 1 0 UBA/TS-N domain U-box PF04564.15 CBK23060.2 - 8.4e-23 80.3 1.8 1.2e-22 79.9 1.8 1.2 1 0 0 1 1 1 1 U-box domain IZUMO PF15005.6 CBK23060.2 - 0.075 13.5 0.1 0.76 10.3 0.0 2.0 1 1 1 2 2 2 0 Izumo sperm-egg fusion, Ig domain-associated DNA_pol_A PF00476.20 CBK23060.2 - 0.12 11.4 0.0 0.13 11.3 0.0 1.1 1 0 0 1 1 1 0 DNA polymerase family A SF3b10 PF07189.11 CBK23061.2 - 1e-23 83.2 0.0 1.1e-23 83.1 0.0 1.0 1 0 0 1 1 1 1 Splicing factor 3B subunit 10 (SF3b10) Macoilin PF09726.9 CBK23062.2 - 4.8 5.6 21.1 6 5.3 21.1 1.2 1 0 0 1 1 1 0 Macoilin family HVSL PF09749.9 CBK23063.2 - 3.2e-37 128.3 0.7 3.8e-37 128.0 0.7 1.0 1 0 0 1 1 1 1 Uncharacterised conserved protein 2_5_RNA_ligase2 PF13563.6 CBK23063.2 - 0.003 17.5 0.0 0.0041 17.0 0.0 1.3 1 0 0 1 1 1 1 2'-5' RNA ligase superfamily Ribosomal_S27e PF01667.17 CBK23064.2 - 2.6e-21 75.1 5.4 2.8e-21 75.0 5.4 1.0 1 0 0 1 1 1 1 Ribosomal protein S27 TF_Zn_Ribbon PF08271.12 CBK23064.2 - 0.0036 16.8 3.2 0.0047 16.4 3.2 1.2 1 0 0 1 1 1 1 TFIIB zinc-binding zf-NADH-PPase PF09297.11 CBK23064.2 - 0.0064 16.1 0.6 0.031 13.9 0.0 2.2 2 0 0 2 2 2 1 NADH pyrophosphatase zinc ribbon domain zinc_ribbon_4 PF13717.6 CBK23064.2 - 0.034 14.1 2.0 4 7.4 0.1 2.5 2 0 0 2 2 2 0 zinc-ribbon domain IBR PF01485.21 CBK23064.2 - 0.088 13.0 3.2 0.11 12.8 3.2 1.2 1 1 0 1 1 1 0 IBR domain, a half RING-finger domain DUF3242 PF11586.8 CBK23065.2 - 0.052 13.3 0.1 0.14 11.9 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3242) Tfb2 PF03849.14 CBK23066.2 - 6e-37 127.4 0.0 7.7e-37 127.1 0.0 1.1 1 0 0 1 1 1 1 Transcription factor Tfb2 Tfb2_C PF18307.1 CBK23067.2 - 0.00014 22.2 0.1 0.00021 21.6 0.1 1.3 1 1 0 1 1 1 1 Transcription factor Tfb2 (p52) C-terminal domain DUF3226 PF11536.8 CBK23067.2 - 0.024 14.3 0.0 0.024 14.3 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3226) Arm PF00514.23 CBK23068.2 - 1.2e-08 34.7 3.6 4.5e-05 23.3 0.2 4.4 4 0 0 4 4 4 3 Armadillo/beta-catenin-like repeat ANAPC10 PF03256.16 CBK23071.2 - 2.6e-33 115.2 0.1 3e-33 115.0 0.1 1.0 1 0 0 1 1 1 1 Anaphase-promoting complex, subunit 10 (APC10) F5_F8_type_C PF00754.25 CBK23071.2 - 9.7e-08 32.2 0.1 1.3e-07 31.8 0.1 1.2 1 0 0 1 1 1 1 F5/8 type C domain ubiquitin PF00240.23 CBK23072.2 - 1e-07 31.6 0.1 1.7e-07 30.9 0.1 1.4 1 1 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 CBK23072.2 - 0.0014 18.4 0.1 0.0034 17.2 0.1 1.7 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF5101 PF17031.5 CBK23072.2 - 0.019 15.0 0.0 0.023 14.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5101) Cob_adeno_trans PF01923.18 CBK23073.2 - 6.5e-56 189.0 0.0 7.9e-56 188.7 0.0 1.1 1 0 0 1 1 1 1 Cobalamin adenosyltransferase SYCE1 PF15233.6 CBK23075.2 - 0.011 15.8 14.0 0.17 11.9 5.3 2.2 2 0 0 2 2 2 0 Synaptonemal complex central element protein 1 DUF745 PF05335.13 CBK23075.2 - 0.027 14.2 6.5 0.036 13.8 1.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF745) DUF2207 PF09972.9 CBK23075.2 - 0.092 11.5 0.2 0.19 10.5 0.0 1.5 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) SNARE PF05739.19 CBK23075.2 - 0.36 10.8 7.1 1.5 8.9 6.1 2.5 2 1 0 2 2 2 0 SNARE domain SP_C-Propep PF08999.10 CBK23075.2 - 0.61 9.9 2.7 1.2 8.9 2.7 1.4 1 0 0 1 1 1 0 Surfactant protein C, N terminal propeptide NPV_P10 PF05531.12 CBK23075.2 - 1.4 9.5 8.5 1.5 9.3 0.9 3.4 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein Cob_adeno_trans PF01923.18 CBK23075.2 - 1.5 9.0 5.3 17 5.5 0.7 2.4 1 1 0 2 2 2 0 Cobalamin adenosyltransferase PPTA PF01239.22 CBK23076.2 - 7.9e-26 89.0 11.0 2e-06 27.3 0.5 5.6 5 0 0 5 5 5 5 Protein prenyltransferase alpha subunit repeat Stap_Strp_tox_C PF02876.17 CBK23076.2 - 0.0073 16.6 1.8 0.13 12.6 0.3 2.3 1 1 1 2 2 2 1 Staphylococcal/Streptococcal toxin, beta-grasp domain TPR_8 PF13181.6 CBK23077.2 - 0.031 14.5 0.0 0.2 11.9 0.1 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat Thioredoxin PF00085.20 CBK23078.2 - 3.9e-30 103.9 0.0 5.1e-30 103.5 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin OST3_OST6 PF04756.13 CBK23078.2 - 1.4e-10 41.0 0.0 2.1e-10 40.4 0.0 1.2 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_2 PF13098.6 CBK23078.2 - 6.9e-05 23.3 0.1 0.00025 21.5 0.1 1.8 1 1 0 1 1 1 1 Thioredoxin-like domain ERp29_N PF07912.13 CBK23078.2 - 7.3e-05 22.9 0.0 0.0001 22.4 0.0 1.2 1 0 0 1 1 1 1 ERp29, N-terminal domain Thioredoxin_7 PF13899.6 CBK23078.2 - 0.0034 17.5 0.0 0.0055 16.9 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_8 PF13905.6 CBK23078.2 - 0.0071 16.7 0.0 0.048 14.0 0.0 2.0 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin_6 PF13848.6 CBK23078.2 - 0.046 13.6 0.0 1.2 9.1 0.0 2.1 1 1 1 2 2 2 0 Thioredoxin-like domain AhpC-TSA PF00578.21 CBK23078.2 - 0.078 12.9 0.0 0.12 12.3 0.0 1.2 1 0 0 1 1 1 0 AhpC/TSA family HyaE PF07449.11 CBK23078.2 - 0.11 12.4 0.0 0.2 11.6 0.0 1.3 1 0 0 1 1 1 0 Hydrogenase-1 expression protein HyaE TraF PF13728.6 CBK23078.2 - 0.17 11.6 0.0 0.27 11.0 0.0 1.2 1 0 0 1 1 1 0 F plasmid transfer operon protein CS PF04969.16 CBK23079.2 - 3e-05 24.9 0.5 8.6e-05 23.5 0.5 1.8 1 1 0 1 1 1 1 CS domain ComP_DUS PF16732.5 CBK23079.2 - 0.13 13.2 0.0 0.24 12.3 0.0 1.4 1 0 0 1 1 1 0 Type IV minor pilin ComP, DNA uptake sequence receptor IF-2B PF01008.17 CBK23080.2 - 4.8e-69 232.7 0.0 5.7e-69 232.4 0.0 1.0 1 0 0 1 1 1 1 Initiation factor 2 subunit family adh_short PF00106.25 CBK23081.2 - 9.3e-21 74.2 0.0 1.1e-20 73.9 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CBK23081.2 - 1.9e-13 50.6 0.0 3.1e-13 49.8 0.0 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CBK23081.2 - 0.0009 19.2 0.0 0.2 11.6 0.0 2.1 2 0 0 2 2 2 2 KR domain Nop PF01798.18 CBK23082.2 - 2.9e-83 278.9 0.3 2.9e-83 278.9 0.3 2.6 3 1 0 3 3 3 1 snoRNA binding domain, fibrillarin NOP5NT PF08156.13 CBK23082.2 - 8.1e-20 71.0 0.5 8.1e-20 71.0 0.5 3.0 2 1 0 2 2 2 1 NOP5NT (NUC127) domain CDC27 PF09507.10 CBK23082.2 - 0.89 8.9 60.6 1.2 8.5 60.6 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Endostatin PF06482.11 CBK23082.2 - 3.3 7.1 19.7 5.7 6.3 19.7 1.3 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin Ribosomal_S17e PF00833.18 CBK23083.2 - 2.2e-55 185.8 1.5 2.6e-55 185.6 1.5 1.0 1 0 0 1 1 1 1 Ribosomal S17 TruD PF01142.18 CBK23084.2 - 4.6e-47 160.8 0.0 1.3e-45 156.0 0.0 2.2 1 1 0 1 1 1 1 tRNA pseudouridine synthase D (TruD) Ribosomal_L22 PF00237.19 CBK23085.2 - 1.2e-15 57.6 0.1 2.3e-15 56.7 0.0 1.6 2 0 0 2 2 2 1 Ribosomal protein L22p/L17e DUF2314 PF10077.9 CBK23085.2 - 0.034 14.2 0.5 0.47 10.5 0.2 2.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2314) LIM PF00412.22 CBK23086.2 - 2.4e-25 88.5 23.8 2e-14 53.5 7.8 2.5 2 0 0 2 2 2 2 LIM domain CH PF00307.31 CBK23086.2 - 3.6e-15 56.1 0.0 5.5e-15 55.5 0.0 1.3 1 0 0 1 1 1 1 Calponin homology (CH) domain Pellino PF04710.14 CBK23086.2 - 0.081 11.6 6.2 1.3 7.6 0.9 2.1 2 0 0 2 2 2 0 Pellino Zn-ribbon_8 PF09723.10 CBK23086.2 - 0.1 12.7 22.8 5.4 7.2 0.1 4.8 4 1 0 4 4 4 0 Zinc ribbon domain DZR PF12773.7 CBK23086.2 - 0.62 10.1 26.1 1.8 8.7 2.6 4.5 1 1 1 2 2 1 0 Double zinc ribbon Sgf11 PF08209.11 CBK23086.2 - 0.73 9.4 15.3 0.93 9.1 0.3 4.6 5 0 0 5 5 5 0 Sgf11 (transcriptional regulation protein) DUF2175 PF09943.9 CBK23086.2 - 1 9.7 13.8 1.5 9.2 0.7 3.8 2 2 2 4 4 4 0 Uncharacterized protein conserved in archaea (DUF2175) zf-C2HC5 PF06221.13 CBK23086.2 - 1.8 8.6 22.7 0.89 9.6 3.5 5.0 4 1 1 5 5 5 0 Putative zinc finger motif, C2HC5-type RecO_C PF02565.15 CBK23086.2 - 3.5 7.4 5.9 1.7 8.4 0.3 2.2 2 0 0 2 2 2 0 Recombination protein O C terminal YdjO PF14169.6 CBK23086.2 - 4.1 7.2 14.5 4.8 7.0 0.2 4.5 4 1 1 5 5 5 0 Cold-inducible protein YdjO DUF3268 PF11672.8 CBK23086.2 - 7.9 6.8 13.7 0.69 10.2 3.1 2.5 2 0 0 2 2 2 0 zinc-finger-containing domain MalM PF07148.12 CBK23087.2 - 0.14 12.0 0.0 0.28 11.0 0.0 1.4 1 0 0 1 1 1 0 Maltose operon periplasmic protein precursor (MalM) DUF676 PF05057.14 CBK23088.2 - 3.4e-22 79.1 0.1 6.6e-22 78.1 0.1 1.4 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Palm_thioest PF02089.15 CBK23088.2 - 0.014 15.2 0.0 0.022 14.6 0.0 1.4 1 0 0 1 1 1 0 Palmitoyl protein thioesterase Abhydrolase_8 PF06259.12 CBK23088.2 - 0.11 12.1 0.0 0.18 11.4 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase Kdo PF06293.14 CBK23088.2 - 0.11 11.8 0.2 0.25 10.7 0.2 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family AAA PF00004.29 CBK23089.2 - 1.8e-15 57.5 0.0 3.6e-15 56.5 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.6 CBK23089.2 - 3e-14 53.1 0.0 5.5e-10 39.3 0.0 2.8 2 1 1 3 3 3 2 DNA polymerase III, delta subunit Rep_fac_C PF08542.11 CBK23089.2 - 4.6e-10 39.8 0.0 1.1e-09 38.5 0.0 1.7 1 0 0 1 1 1 1 Replication factor C C-terminal domain Rad17 PF03215.15 CBK23089.2 - 2.3e-07 30.9 0.0 3.5e-06 27.1 0.0 2.2 1 1 0 1 1 1 1 Rad17 P-loop domain RuvB_N PF05496.12 CBK23089.2 - 1.5e-06 28.1 0.0 4.6e-06 26.5 0.0 1.9 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_14 PF13173.6 CBK23089.2 - 5.6e-06 26.4 0.0 1.9e-05 24.7 0.0 1.9 2 1 0 2 2 1 1 AAA domain AAA_22 PF13401.6 CBK23089.2 - 1e-05 25.8 0.3 0.0089 16.3 0.3 2.6 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 CBK23089.2 - 3.6e-05 23.6 0.0 0.00019 21.2 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.6 CBK23089.2 - 4.4e-05 23.4 0.0 0.00026 20.9 0.0 1.9 1 1 1 2 2 2 1 AAA domain DUF815 PF05673.13 CBK23089.2 - 7.1e-05 22.1 0.0 0.00013 21.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_assoc_2 PF16193.5 CBK23089.2 - 0.0001 22.6 0.2 0.00042 20.6 0.2 2.1 1 1 0 1 1 1 1 AAA C-terminal domain AAA_19 PF13245.6 CBK23089.2 - 0.00014 22.2 0.0 0.00035 20.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 CBK23089.2 - 0.0002 21.8 0.0 0.00063 20.2 0.0 2.2 1 1 0 1 1 1 1 AAA ATPase domain ResIII PF04851.15 CBK23089.2 - 0.00053 20.0 0.0 0.019 15.0 0.0 2.1 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit AAA_5 PF07728.14 CBK23089.2 - 0.00092 19.2 0.2 0.0031 17.5 0.2 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_7 PF12775.7 CBK23089.2 - 0.0023 17.4 0.0 0.0041 16.7 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region TniB PF05621.11 CBK23089.2 - 0.0024 17.3 0.1 0.49 9.8 0.0 2.4 1 1 1 2 2 2 1 Bacterial TniB protein AAA_23 PF13476.6 CBK23089.2 - 0.0025 18.4 0.0 0.0036 17.8 0.0 1.4 1 1 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 CBK23089.2 - 0.0032 16.9 0.1 0.035 13.5 0.1 2.0 1 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI DEAD PF00270.29 CBK23089.2 - 0.0039 17.0 0.3 0.052 13.3 0.0 2.2 1 1 1 2 2 2 1 DEAD/DEAH box helicase DNA_pol3_delta PF06144.13 CBK23089.2 - 0.0075 16.1 0.0 0.013 15.3 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA_18 PF13238.6 CBK23089.2 - 0.0092 16.5 0.0 0.016 15.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain PhoH PF02562.16 CBK23089.2 - 0.0099 15.4 0.0 5 6.5 0.0 2.4 2 0 0 2 2 2 0 PhoH-like protein T2SSE PF00437.20 CBK23089.2 - 0.012 14.7 0.0 0.041 12.9 0.0 1.8 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_24 PF13479.6 CBK23089.2 - 0.012 15.3 0.0 0.023 14.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_3 PF07726.11 CBK23089.2 - 0.014 15.2 0.0 0.027 14.3 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 CBK23089.2 - 0.02 15.3 0.0 0.039 14.3 0.0 1.6 1 0 0 1 1 1 0 RNA helicase SRP54 PF00448.22 CBK23089.2 - 0.027 14.1 0.0 0.046 13.4 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain Viral_helicase1 PF01443.18 CBK23089.2 - 0.033 13.9 0.0 0.053 13.2 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_29 PF13555.6 CBK23089.2 - 0.037 13.8 0.0 0.081 12.7 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain MCM PF00493.23 CBK23089.2 - 0.037 13.1 0.0 0.063 12.4 0.0 1.3 1 0 0 1 1 1 0 MCM P-loop domain SNF2_N PF00176.23 CBK23089.2 - 0.04 12.6 0.0 0.084 11.6 0.0 1.4 1 0 0 1 1 1 0 SNF2 family N-terminal domain AAA_33 PF13671.6 CBK23089.2 - 0.05 13.8 0.0 0.098 12.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 CBK23089.2 - 0.052 13.3 0.0 0.1 12.3 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_28 PF13521.6 CBK23089.2 - 0.057 13.7 0.0 0.12 12.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain DUF5343 PF17278.2 CBK23089.2 - 0.091 12.8 0.0 0.18 11.9 0.0 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5343) ATPase_2 PF01637.18 CBK23089.2 - 0.092 12.6 0.0 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_27 PF13514.6 CBK23089.2 - 0.094 12.3 0.0 0.18 11.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 CBK23089.2 - 0.098 13.2 0.0 0.28 11.7 0.0 1.7 1 1 0 1 1 1 0 ABC transporter MCM PF00493.23 CBK23090.2 - 8e-100 332.5 0.1 1.2e-99 332.0 0.1 1.2 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 CBK23090.2 - 8.4e-38 129.1 0.0 1.8e-37 128.0 0.0 1.6 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 CBK23090.2 - 2.1e-25 88.9 1.0 7.6e-25 87.2 1.0 2.0 1 0 0 1 1 1 1 MCM AAA-lid domain MCM6_C PF18263.1 CBK23090.2 - 4.9e-14 52.5 0.5 4.9e-14 52.5 0.5 2.2 2 0 0 2 2 2 1 MCM6 C-terminal winged-helix domain MCM_N PF14551.6 CBK23090.2 - 3.4e-10 40.4 0.0 9.8e-10 39.0 0.0 1.8 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 CBK23090.2 - 1e-05 25.0 0.0 8.9e-05 22.0 0.0 2.2 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 CBK23090.2 - 0.00099 19.1 0.0 0.0024 17.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 CBK23090.2 - 0.0036 17.2 0.0 0.0087 15.9 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 CBK23090.2 - 0.035 13.8 0.0 0.08 12.7 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain LSM PF01423.22 CBK23091.2 - 6e-21 73.9 0.1 6.6e-21 73.8 0.1 1.0 1 0 0 1 1 1 1 LSM domain DEAD PF00270.29 CBK23092.2 - 1.3e-43 148.8 0.0 2e-43 148.2 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CBK23092.2 - 6.8e-24 84.4 0.0 2.5e-23 82.5 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 CBK23092.2 - 3.3e-09 36.8 0.0 6.9e-09 35.8 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 CBK23092.2 - 0.022 14.8 0.2 0.053 13.5 0.0 1.7 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit efThoc1 PF11957.8 CBK23094.2 - 8.5e-33 113.8 0.6 6.6e-32 110.8 0.6 2.0 1 1 0 1 1 1 1 THO complex subunit 1 transcription elongation factor Guanylate_kin PF00625.21 CBK23096.2 - 5.4e-59 198.9 0.0 6.6e-59 198.7 0.0 1.0 1 0 0 1 1 1 1 Guanylate kinase AAA_33 PF13671.6 CBK23096.2 - 3.4e-05 24.0 0.0 0.00032 20.9 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 CBK23096.2 - 5.8e-05 23.6 0.1 0.00011 22.8 0.1 1.6 1 1 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 CBK23096.2 - 0.0003 20.7 0.0 0.00067 19.6 0.0 1.6 1 0 0 1 1 1 1 RsgA GTPase AAA_22 PF13401.6 CBK23096.2 - 0.00047 20.5 0.0 0.0013 19.1 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 CBK23096.2 - 0.00062 20.2 0.0 0.0012 19.2 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain MMR_HSR1 PF01926.23 CBK23096.2 - 0.00081 19.5 0.0 0.0019 18.3 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase RNA_helicase PF00910.22 CBK23096.2 - 0.00081 19.7 0.0 0.0022 18.3 0.0 1.9 2 1 0 2 2 2 1 RNA helicase Roc PF08477.13 CBK23096.2 - 0.002 18.3 0.0 0.0046 17.2 0.0 1.7 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase AAA_7 PF12775.7 CBK23096.2 - 0.0023 17.5 0.0 0.0038 16.8 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_5 PF07728.14 CBK23096.2 - 0.0027 17.7 0.3 0.018 15.0 0.0 2.4 1 1 1 2 2 2 1 AAA domain (dynein-related subfamily) ATPase_2 PF01637.18 CBK23096.2 - 0.0035 17.3 0.0 0.0055 16.6 0.0 1.3 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea AAA PF00004.29 CBK23096.2 - 0.02 15.3 0.0 0.05 14.0 0.0 1.8 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.27 CBK23096.2 - 0.044 14.3 0.1 0.074 13.6 0.1 1.6 1 1 0 1 1 1 0 ABC transporter AAA_29 PF13555.6 CBK23096.2 - 0.12 12.2 0.0 0.21 11.4 0.0 1.3 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_24 PF13479.6 CBK23096.2 - 0.13 12.0 0.1 0.38 10.5 0.0 1.7 2 1 1 3 3 3 0 AAA domain DUF815 PF05673.13 CBK23096.2 - 0.13 11.4 0.0 0.23 10.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Pkinase PF00069.25 CBK23097.2 - 1.4e-57 195.1 0.0 2.1e-57 194.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBK23097.2 - 3.9e-26 91.9 0.0 6e-26 91.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase EF-hand_7 PF13499.6 CBK23097.2 - 5.6e-17 62.0 20.0 1.1e-08 35.4 0.5 2.9 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.6 CBK23097.2 - 1.6e-13 49.4 5.7 9.6e-06 25.1 0.6 3.9 3 0 0 3 3 3 3 EF-hand domain EF-hand_1 PF00036.32 CBK23097.2 - 2.5e-13 48.5 7.4 6.8e-06 25.3 1.3 3.8 3 0 0 3 3 3 3 EF hand EF-hand_8 PF13833.6 CBK23097.2 - 1.6e-05 24.7 10.9 0.0014 18.4 4.0 3.9 2 1 2 4 4 4 3 EF-hand domain pair EF-hand_5 PF13202.6 CBK23097.2 - 2.1e-05 23.8 4.3 0.0068 15.9 1.0 3.9 3 0 0 3 3 3 2 EF hand Pkinase_fungal PF17667.1 CBK23097.2 - 0.0002 20.3 0.1 0.00032 19.6 0.1 1.2 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 CBK23097.2 - 0.0033 16.4 0.1 0.0054 15.7 0.1 1.3 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 CBK23097.2 - 0.023 14.6 0.0 0.19 11.6 0.0 2.1 2 0 0 2 2 2 0 Phosphotransferase enzyme family Choline_kinase PF01633.20 CBK23097.2 - 0.034 13.8 0.1 0.19 11.3 0.1 2.1 2 0 0 2 2 2 0 Choline/ethanolamine kinase Pkinase PF00069.25 CBK23098.2 - 1.9e-57 194.7 0.0 1.9e-56 191.4 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBK23098.2 - 2e-29 102.7 0.0 6.8e-25 87.8 0.0 2.1 1 1 1 2 2 2 2 Protein tyrosine kinase APH PF01636.23 CBK23098.2 - 8.4e-05 22.6 0.0 0.0028 17.6 0.0 2.3 2 0 0 2 2 2 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 CBK23098.2 - 0.00019 20.5 0.2 0.00031 19.8 0.2 1.3 1 0 0 1 1 1 1 Haspin like kinase domain Pox_ser-thr_kin PF05445.11 CBK23098.2 - 0.0055 15.7 0.0 0.0083 15.1 0.0 1.2 1 0 0 1 1 1 1 Poxvirus serine/threonine protein kinase Pkinase_fungal PF17667.1 CBK23098.2 - 0.018 13.8 0.0 0.03 13.1 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase Choline_kinase PF01633.20 CBK23098.2 - 0.044 13.4 0.0 0.068 12.8 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase RIO1 PF01163.22 CBK23098.2 - 0.056 13.0 0.0 0.16 11.6 0.0 1.8 2 0 0 2 2 2 0 RIO1 family zf-Di19 PF05605.12 CBK23099.2 - 0.015 15.6 19.5 2.6 8.4 0.1 4.4 3 1 1 4 4 4 0 Drought induced 19 protein (Di19), zinc-binding PEPCK_ATP PF01293.20 CBK23100.2 - 0.0089 14.7 0.0 0.012 14.3 0.0 1.2 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase DNA_pol_A PF00476.20 CBK23101.2 - 5.3e-93 312.1 0.1 6.6e-93 311.7 0.1 1.1 1 0 0 1 1 1 1 DNA polymerase family A GATase_5 PF13507.6 CBK23101.2 - 0.16 11.1 0.1 0.25 10.4 0.1 1.3 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain nsp7 PF08716.10 CBK23101.2 - 1.3 9.7 6.0 1.5 9.5 3.2 2.5 2 1 0 2 2 2 0 nsp7 replicase PIN_6 PF17146.4 CBK23103.2 - 4.1e-26 91.3 0.1 1.2e-25 89.8 0.1 1.8 1 0 0 1 1 1 1 PIN domain of ribonuclease zf-CCCH_4 PF18044.1 CBK23103.2 - 1.4e-05 24.8 5.1 2.7e-05 23.8 5.1 1.5 1 0 0 1 1 1 1 CCCH-type zinc finger Pullulanase_Ins PF18494.1 CBK23103.2 - 0.068 13.6 0.2 0.6 10.6 0.1 2.5 2 0 0 2 2 2 0 Pullulanase Ins domain zf-CCCH_2 PF14608.6 CBK23103.2 - 1.6 9.3 7.0 3.4 8.3 7.0 1.6 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger zf_CCCH_4 PF18345.1 CBK23103.2 - 2.4 8.3 6.5 4.2 7.6 6.5 1.4 1 0 0 1 1 1 0 Zinc finger domain CPSF_A PF03178.15 CBK23104.2 - 5.1e-11 42.5 0.0 6.7e-11 42.1 0.0 1.1 1 0 0 1 1 1 1 CPSF A subunit region DUF2713 PF10897.8 CBK23104.2 - 0.033 13.9 0.1 0.05 13.3 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2713) Xpo1 PF08389.12 CBK23106.2 - 4.1e-13 49.7 9.1 6e-12 45.9 3.3 3.0 3 0 0 3 3 3 2 Exportin 1-like protein IBN_N PF03810.19 CBK23106.2 - 0.024 14.6 0.1 0.024 14.6 0.1 2.4 2 0 0 2 2 2 0 Importin-beta N-terminal domain UTP15_C PF09384.10 CBK23106.2 - 0.03 14.0 0.0 9.7 5.9 0.0 2.8 2 0 0 2 2 2 0 UTP15 C terminal HEAT_2 PF13646.6 CBK23106.2 - 0.032 14.6 0.1 0.21 12.0 0.0 2.4 3 0 0 3 3 3 0 HEAT repeats Arm PF00514.23 CBK23106.2 - 0.12 12.4 0.3 9.8 6.4 0.0 3.2 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat CAAP1 PF15335.6 CBK23106.2 - 0.18 12.4 1.3 3 8.4 0.1 3.4 2 1 0 2 2 2 0 Caspase activity and apoptosis inhibitor 1 Mito_carr PF00153.27 CBK23107.2 - 5.7e-77 253.8 3.2 1.2e-24 86.1 0.3 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 CBK23107.2 - 0.025 13.7 1.7 1.4 8.1 0.2 2.9 2 1 0 3 3 3 0 Gammaproteobacterial serine protease HAP PF03866.13 CBK23107.2 - 0.068 13.2 0.3 0.54 10.2 0.2 2.0 2 0 0 2 2 2 0 Hydrophobic abundant protein (HAP) UCR_Fe-S_N PF10399.9 CBK23107.2 - 0.49 9.8 4.9 0.14 11.5 1.6 1.7 2 0 0 2 2 2 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal EF-hand_6 PF13405.6 CBK23108.2 - 2.5e-08 33.2 1.4 0.053 13.5 0.0 4.2 4 0 0 4 4 4 2 EF-hand domain EF-hand_1 PF00036.32 CBK23108.2 - 5.7e-08 31.8 0.4 0.026 14.1 0.0 4.3 4 0 0 4 4 4 2 EF hand EF-hand_7 PF13499.6 CBK23108.2 - 4.1e-05 23.9 3.4 0.012 16.0 2.4 3.3 2 1 0 2 2 2 1 EF-hand domain pair EF-hand_5 PF13202.6 CBK23108.2 - 0.00038 19.8 0.2 0.11 12.1 0.0 3.8 4 0 0 4 4 4 1 EF hand DUF2934 PF11154.8 CBK23108.2 - 0.00081 19.0 0.3 0.0017 18.0 0.3 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2934) EF-hand_8 PF13833.6 CBK23108.2 - 0.017 15.0 0.3 0.32 10.9 0.0 3.0 4 0 0 4 4 4 0 EF-hand domain pair Cbl_N2 PF02761.14 CBK23108.2 - 0.035 14.8 0.2 0.16 12.7 0.0 2.1 2 0 0 2 2 2 0 CBL proto-oncogene N-terminus, EF hand-like domain DEAD PF00270.29 CBK23110.2 - 2.8e-10 40.3 0.7 1.7e-09 37.7 0.1 2.4 2 1 0 2 2 2 1 DEAD/DEAH box helicase PA28_beta PF02252.18 CBK23110.2 - 0.00017 21.3 0.0 0.00031 20.4 0.0 1.4 1 0 0 1 1 1 1 Proteasome activator pa28 beta subunit AnfO_nitrog PF09582.10 CBK23110.2 - 0.02 14.2 0.0 0.031 13.6 0.0 1.2 1 0 0 1 1 1 0 Iron only nitrogenase protein AnfO (AnfO_nitrog) Myb_DNA-bind_6 PF13921.6 CBK23111.2 - 7.2e-20 71.0 6.1 2.4e-12 46.9 1.8 2.9 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 CBK23111.2 - 7.3e-19 67.7 7.4 1.2e-10 41.4 1.5 2.6 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_Cef PF11831.8 CBK23111.2 - 1.7e-13 50.7 8.6 1.7e-13 50.7 8.6 3.4 3 0 0 3 3 3 1 pre-mRNA splicing factor component Rap1_C PF11626.8 CBK23111.2 - 0.046 13.8 0.2 11 6.2 0.3 3.4 3 1 0 3 3 3 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain SANT_DAMP1_like PF16282.5 CBK23111.2 - 0.077 13.2 0.8 0.36 11.1 0.8 2.2 1 0 0 1 1 1 0 SANT/Myb-like domain of DAMP1 GTP_EFTU PF00009.27 CBK23112.2 - 7.8e-64 214.8 0.1 1.8e-63 213.6 0.1 1.6 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 CBK23112.2 - 4.9e-26 90.9 0.0 1.3e-25 89.5 0.0 1.8 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.24 CBK23112.2 - 3.5e-20 71.8 0.0 7.9e-20 70.7 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.6 CBK23112.2 - 1.3e-14 54.1 0.0 3.7e-14 52.6 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.25 CBK23112.2 - 7.6e-14 51.9 0.1 2e-13 50.5 0.1 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 CBK23112.2 - 0.00021 21.4 0.1 0.00096 19.2 0.1 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase Carboxyl_trans PF01039.22 CBK23113.2 - 4.9e-190 632.4 0.1 5.8e-190 632.1 0.1 1.0 1 0 0 1 1 1 1 Carboxyl transferase domain MdcE PF06833.11 CBK23113.2 - 0.0093 15.5 0.0 0.03 13.8 0.0 1.8 3 0 0 3 3 3 1 Malonate decarboxylase gamma subunit (MdcE) DNA_pol3_delta2 PF13177.6 CBK23114.2 - 6.5e-12 45.5 0.3 1.1e-11 44.7 0.3 1.4 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA PF00004.29 CBK23114.2 - 6.8e-08 33.0 0.0 1.5e-07 31.9 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 CBK23114.2 - 0.00015 21.7 0.1 0.00026 21.0 0.1 1.3 1 0 0 1 1 1 1 Rad17 P-loop domain DUF815 PF05673.13 CBK23114.2 - 0.0069 15.6 0.0 0.012 14.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_16 PF13191.6 CBK23114.2 - 0.0085 16.5 0.0 0.079 13.3 0.0 2.4 1 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 CBK23114.2 - 0.01 16.1 0.1 0.054 13.8 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 CBK23114.2 - 0.048 13.8 0.0 0.15 12.2 0.0 1.9 1 1 0 1 1 1 0 AAA domain Bac_DnaA PF00308.18 CBK23114.2 - 0.074 12.9 0.0 2.4 7.9 0.0 2.5 2 0 0 2 2 2 0 Bacterial dnaA protein DNA_pol3_delta PF06144.13 CBK23114.2 - 0.075 12.8 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 DNA polymerase III, delta subunit UPF0126 PF03458.13 CBK23115.2 - 0.00028 20.7 1.0 0.00028 20.7 1.0 2.4 2 0 0 2 2 2 1 UPF0126 domain LRR_8 PF13855.6 CBK23116.2 - 0.0052 16.5 0.5 0.098 12.4 0.1 2.8 3 1 0 3 3 3 1 Leucine rich repeat LRR_4 PF12799.7 CBK23116.2 - 0.032 14.7 1.6 0.27 11.7 0.2 3.0 1 1 2 3 3 3 0 Leucine Rich repeats (2 copies) CPSase_L_D2 PF02786.17 CBK23117.2 - 2e-72 243.1 0.0 3.3e-72 242.4 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 CBK23117.2 - 6.6e-44 149.0 0.0 1.6e-43 147.7 0.0 1.7 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 CBK23117.2 - 1.9e-36 124.4 0.0 4.2e-36 123.3 0.0 1.6 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.22 CBK23117.2 - 4.5e-18 64.9 0.2 9.6e-18 63.8 0.2 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme PCC_BT PF18140.1 CBK23117.2 - 1.6e-10 41.4 0.1 1.4e-05 25.4 0.0 2.5 1 1 1 2 2 2 2 Propionyl-coenzyme A carboxylase BT domain Biotin_lipoyl_2 PF13533.6 CBK23117.2 - 2.9e-08 33.4 0.1 1.6e-07 31.1 0.0 2.1 1 1 1 2 2 2 1 Biotin-lipoyl like Dala_Dala_lig_C PF07478.13 CBK23117.2 - 8e-08 32.1 0.1 3.5e-07 30.0 0.0 2.0 1 1 1 2 2 2 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 CBK23117.2 - 2.5e-05 23.9 0.0 5.3e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain DUF2118 PF09891.9 CBK23117.2 - 0.0022 18.0 0.0 0.0054 16.7 0.0 1.6 1 0 0 1 1 1 1 Uncharacterized protein conserved in archaea (DUF2118) GCV_H PF01597.19 CBK23117.2 - 0.003 17.5 0.1 0.011 15.6 0.1 2.0 1 0 0 1 1 1 1 Glycine cleavage H-protein PTS_EIIA_1 PF00358.20 CBK23117.2 - 0.0036 17.1 0.0 0.01 15.6 0.0 1.8 1 0 0 1 1 1 1 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 Peptidase_M23 PF01551.22 CBK23117.2 - 0.026 14.7 0.1 0.29 11.4 0.0 2.3 2 0 0 2 2 2 0 Peptidase family M23 RnfC_N PF13375.6 CBK23117.2 - 0.05 13.6 0.0 0.12 12.3 0.0 1.6 1 0 0 1 1 1 0 RnfC Barrel sandwich hybrid domain PYNP_C PF07831.13 CBK23117.2 - 0.064 12.9 0.0 0.2 11.3 0.0 1.8 1 0 0 1 1 1 0 Pyrimidine nucleoside phosphorylase C-terminal domain HlyD_D23 PF16576.5 CBK23117.2 - 0.092 11.9 0.0 0.19 10.9 0.0 1.5 1 0 0 1 1 1 0 Barrel-sandwich domain of CusB or HlyD membrane-fusion HlyD_3 PF13437.6 CBK23117.2 - 0.12 13.1 0.2 0.49 11.1 0.1 2.2 2 1 0 2 2 2 0 HlyD family secretion protein TF_Otx PF03529.13 CBK23118.2 - 0.00051 20.4 1.0 0.51 10.8 1.2 2.5 2 0 0 2 2 2 2 Otx1 transcription factor Fez1 PF06818.15 CBK23118.2 - 0.0015 19.0 9.1 0.0024 18.3 9.1 1.2 1 0 0 1 1 1 1 Fez1 GAS PF13851.6 CBK23118.2 - 0.008 15.6 14.9 0.008 15.6 14.9 2.0 2 1 1 3 3 3 1 Growth-arrest specific micro-tubule binding FUSC PF04632.12 CBK23118.2 - 0.31 9.5 6.0 0.36 9.3 6.0 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family AAA_23 PF13476.6 CBK23118.2 - 1.2 9.6 6.1 1.8 9.0 6.1 1.3 1 0 0 1 1 1 0 AAA domain APG6_N PF17675.1 CBK23118.2 - 5 7.6 23.1 8.7 6.9 21.0 2.2 1 1 1 2 2 2 0 Apg6 coiled-coil region HAUS6_N PF14661.6 CBK23118.2 - 7 6.2 13.5 2.7 7.5 10.3 1.8 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus DUF724 PF05266.14 CBK23118.2 - 9.1 6.1 14.9 4.9 6.9 12.0 2.0 2 1 1 3 3 3 0 Protein of unknown function (DUF724) Ras PF00071.22 CBK23119.2 - 1.2e-60 203.8 0.2 1.4e-60 203.6 0.2 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CBK23119.2 - 4.8e-33 113.9 0.1 9.1e-33 113.0 0.0 1.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CBK23119.2 - 2.6e-12 46.6 0.1 3.3e-12 46.2 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 CBK23119.2 - 2.5e-05 24.3 0.0 4e-05 23.7 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 CBK23119.2 - 5.6e-05 23.1 0.1 0.35 10.8 0.0 2.3 1 1 0 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 CBK23119.2 - 0.0004 20.0 0.0 0.0025 17.4 0.0 2.0 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 CBK23119.2 - 0.00083 18.8 0.0 0.0014 18.0 0.0 1.4 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region DAP3 PF10236.9 CBK23119.2 - 0.069 12.3 0.0 0.14 11.3 0.0 1.4 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 AAA_24 PF13479.6 CBK23119.2 - 0.086 12.6 0.2 0.26 11.0 0.2 2.0 1 1 0 1 1 1 0 AAA domain AAA_22 PF13401.6 CBK23119.2 - 0.11 12.7 0.1 0.24 11.7 0.1 1.8 1 1 0 1 1 1 0 AAA domain DNA_pol_E_B PF04042.16 CBK23119.2 - 0.18 11.1 0.0 0.24 10.7 0.0 1.1 1 0 0 1 1 1 0 DNA polymerase alpha/epsilon subunit B Ribosomal_L30 PF00327.20 CBK23121.2 - 4.2e-18 65.0 0.7 8e-18 64.1 0.7 1.5 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e Ribosomal_L30_N PF08079.12 CBK23121.2 - 2e-12 47.2 10.2 3.7e-12 46.3 10.2 1.4 1 0 0 1 1 1 1 Ribosomal L30 N-terminal domain Bro-N PF02498.17 CBK23121.2 - 0.072 13.8 0.2 0.16 12.7 0.2 1.6 1 0 0 1 1 1 0 BRO family, N-terminal domain Guanylate_cyc PF00211.20 CBK23121.2 - 0.093 12.3 0.0 0.17 11.5 0.0 1.3 1 0 0 1 1 1 0 Adenylate and Guanylate cyclase catalytic domain Pro_isomerase PF00160.21 CBK23122.2 - 3.6e-47 160.6 0.0 4.1e-47 160.4 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Glycos_transf_2 PF00535.26 CBK23123.2 - 4.3e-22 78.7 0.0 8.5e-22 77.7 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_2 PF10111.9 CBK23123.2 - 8.5e-11 41.8 0.0 2.1e-10 40.5 0.0 1.6 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_tranf_2_3 PF13641.6 CBK23123.2 - 3.2e-05 23.9 0.0 4.6e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_4 PF13704.6 CBK23123.2 - 0.0012 19.4 0.0 0.0055 17.2 0.0 2.2 2 1 0 2 2 2 1 Glycosyl transferase family 2 Glyco_transf_7C PF02709.14 CBK23123.2 - 0.015 14.9 0.0 0.033 13.9 0.0 1.5 1 0 0 1 1 1 0 N-terminal domain of galactosyltransferase Anp1 PF03452.14 CBK23123.2 - 0.031 13.7 0.0 0.15 11.4 0.0 1.8 1 1 0 2 2 2 0 Anp1 PolyG_pol PF01518.16 CBK23124.2 - 0.016 13.9 0.0 0.031 13.0 0.0 1.4 1 0 0 1 1 1 0 Sigma NS protein UQ_con PF00179.26 CBK23125.2 - 2.4e-40 137.4 0.0 3.5e-40 136.9 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 CBK23125.2 - 0.019 14.7 0.0 0.03 14.0 0.0 1.4 1 0 0 1 1 1 0 Prokaryotic E2 family B RWD PF05773.22 CBK23125.2 - 0.14 12.4 0.0 0.28 11.5 0.0 1.6 1 1 0 1 1 1 0 RWD domain Ribo_biogen_C PF04034.13 CBK23127.2 - 1.3e-49 167.1 0.0 1.8e-49 166.7 0.0 1.2 1 0 0 1 1 1 1 Ribosome biogenesis protein, C-terminal RLI PF04068.15 CBK23127.2 - 1.4e-12 47.2 0.1 2.7e-12 46.3 0.1 1.4 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI A_deamin PF02137.18 CBK23128.2 - 7.5e-79 265.6 0.1 9.5e-79 265.2 0.1 1.1 1 0 0 1 1 1 1 Adenosine-deaminase (editase) domain DUF3150 PF11348.8 CBK23128.2 - 0.028 13.7 0.2 0.058 12.6 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3150) Fer2 PF00111.27 CBK23129.2 - 2.3e-13 49.9 2.7 3.4e-13 49.3 2.7 1.3 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Aa_trans PF01490.18 CBK23130.2 - 9.3e-26 90.5 22.7 1.1e-25 90.2 22.7 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DUF2427 PF10348.9 CBK23130.2 - 2.3 8.1 9.2 0.42 10.4 4.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF2427) H_PPase PF03030.16 CBK23132.2 - 2e-256 852.8 24.4 2.3e-256 852.6 24.4 1.0 1 0 0 1 1 1 1 Inorganic H+ pyrophosphatase Ribosomal_L2_C PF03947.18 CBK23133.2 - 1.4e-45 154.6 1.6 2.1e-45 154.0 1.6 1.2 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 CBK23133.2 - 1.2e-14 54.0 0.1 3.4e-14 52.6 0.0 1.9 2 0 0 2 2 2 1 Ribosomal Proteins L2, RNA binding domain Phosphorylase PF00343.20 CBK23134.2 - 5e-280 930.8 0.0 6.3e-280 930.5 0.0 1.0 1 0 0 1 1 1 1 Carbohydrate phosphorylase GTP_EFTU PF00009.27 CBK23136.2 - 2.9e-40 137.9 0.0 4.1e-40 137.4 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFTUD2 PF16004.5 CBK23136.2 - 6e-26 91.4 9.4 6e-26 91.4 9.4 2.0 2 1 0 2 2 2 1 116 kDa U5 small nuclear ribonucleoprotein component N-terminus EFG_IV PF03764.18 CBK23136.2 - 8.7e-21 73.9 0.0 1.8e-20 72.9 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.24 CBK23136.2 - 7.7e-18 64.3 0.0 1.5e-17 63.4 0.0 1.5 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 CBK23136.2 - 1.2e-08 35.2 0.0 3e-08 33.9 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.6 CBK23136.2 - 3.7e-07 30.1 0.0 9.4e-07 28.8 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.23 CBK23136.2 - 0.00022 21.3 0.0 0.00045 20.3 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase TGT PF01702.18 CBK23137.2 - 1.3e-55 189.0 0.1 1.6e-55 188.7 0.1 1.0 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase Suppressor_APC PF11414.8 CBK23137.2 - 0.044 13.8 0.8 0.097 12.8 0.8 1.6 1 0 0 1 1 1 0 Adenomatous polyposis coli tumour suppressor protein Mak10 PF04112.13 CBK23138.2 - 7.8e-11 41.8 0.4 1.1e-10 41.2 0.4 1.2 1 0 0 1 1 1 1 Mak10 subunit, NatC N(alpha)-terminal acetyltransferase AAA_6 PF12774.7 CBK23139.2 - 1.2e-136 455.1 0.0 5.3e-134 446.3 0.0 3.7 3 0 0 3 3 2 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 CBK23139.2 - 3e-113 378.9 17.1 3e-113 378.9 17.1 5.2 4 2 0 4 4 3 1 Dynein heavy chain, N-terminal region 2 DHC_N1 PF08385.12 CBK23139.2 - 1.5e-84 284.6 13.9 1.5e-84 284.6 13.9 4.7 4 2 1 5 5 5 1 Dynein heavy chain, N-terminal region 1 AAA_9 PF12781.7 CBK23139.2 - 1.7e-72 243.2 0.9 1.7e-72 243.2 0.9 3.8 3 0 0 3 3 2 1 ATP-binding dynein motor region AAA_8 PF12780.7 CBK23139.2 - 9.8e-65 218.4 0.0 2.8e-63 213.7 0.0 2.9 2 0 0 2 2 2 1 P-loop containing dynein motor region D4 AAA_7 PF12775.7 CBK23139.2 - 8.4e-45 152.5 0.0 4.5e-37 127.3 0.0 4.7 4 0 0 4 4 4 2 P-loop containing dynein motor region Dynein_C PF18199.1 CBK23139.2 - 1.2e-35 123.2 0.7 1.2e-35 123.2 0.7 2.3 2 0 0 2 2 1 1 Dynein heavy chain C-terminal domain AAA_5 PF07728.14 CBK23139.2 - 3.3e-33 114.6 0.0 2.7e-15 56.6 0.0 7.1 6 2 0 6 6 5 4 AAA domain (dynein-related subfamily) AAA_lid_11 PF18198.1 CBK23139.2 - 5.1e-29 101.2 0.0 1.6e-28 99.6 0.0 1.9 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 CBK23139.2 - 1.1e-27 96.5 0.0 6e-24 84.4 0.0 4.0 3 0 0 3 3 2 1 Dynein heavy chain region D6 P-loop domain MT PF12777.7 CBK23139.2 - 4.8e-26 91.6 6.6 1.1e-25 90.4 6.6 1.6 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor Dynein_AAA_lid PF17852.1 CBK23139.2 - 9.2e-19 67.8 0.0 6.9e-18 65.0 0.0 2.7 2 0 0 2 2 1 1 Dynein heavy chain AAA lid domain AAA PF00004.29 CBK23139.2 - 2.6e-17 63.5 0.0 0.00015 22.2 0.0 5.7 5 0 0 5 5 4 3 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 CBK23139.2 - 2.7e-15 56.8 3.6 0.00021 21.6 0.0 7.2 7 0 0 7 7 5 3 AAA domain AAA_16 PF13191.6 CBK23139.2 - 3.7e-15 56.7 0.5 0.0032 17.9 0.0 7.1 6 0 0 6 6 5 3 AAA ATPase domain AAA_18 PF13238.6 CBK23139.2 - 3.5e-09 37.3 0.0 0.59 10.7 0.0 6.0 4 0 0 4 4 4 2 AAA domain AAA_33 PF13671.6 CBK23139.2 - 7e-09 36.0 0.0 0.062 13.5 0.0 5.5 4 0 0 4 4 4 2 AAA domain AAA_30 PF13604.6 CBK23139.2 - 4.8e-06 26.4 0.4 2.1 8.0 0.0 5.0 5 0 0 5 5 4 1 AAA domain AAA_29 PF13555.6 CBK23139.2 - 6.7e-06 25.8 0.1 0.11 12.2 0.0 3.6 3 0 0 3 3 3 1 P-loop containing region of AAA domain Mg_chelatase PF01078.21 CBK23139.2 - 1.1e-05 24.9 0.3 2.1 7.7 0.0 4.7 5 0 0 5 5 5 2 Magnesium chelatase, subunit ChlI AAA_14 PF13173.6 CBK23139.2 - 1.4e-05 25.1 0.0 2.2 8.3 0.0 5.3 5 0 0 5 5 4 1 AAA domain T2SSE PF00437.20 CBK23139.2 - 1.8e-05 23.9 2.0 0.28 10.2 0.0 4.5 4 0 0 4 4 4 1 Type II/IV secretion system protein NACHT PF05729.12 CBK23139.2 - 8.8e-05 22.5 0.1 9.2 6.2 0.0 5.5 4 0 0 4 4 4 0 NACHT domain TsaE PF02367.17 CBK23139.2 - 0.00012 22.1 0.9 1 9.4 0.0 4.2 4 0 0 4 4 4 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_24 PF13479.6 CBK23139.2 - 0.00012 21.8 1.2 11 5.7 0.0 5.3 5 0 0 5 5 5 0 AAA domain FtsK_SpoIIIE PF01580.18 CBK23139.2 - 0.00028 20.3 0.0 3 7.1 0.0 4.0 4 0 0 4 4 4 1 FtsK/SpoIIIE family AAA_19 PF13245.6 CBK23139.2 - 0.00038 20.8 7.0 0.18 12.1 0.0 6.0 7 0 0 7 7 5 1 AAA domain RNA_helicase PF00910.22 CBK23139.2 - 0.00046 20.6 0.0 7.4 7.0 0.0 5.0 4 0 0 4 4 4 0 RNA helicase IstB_IS21 PF01695.17 CBK23139.2 - 0.00054 19.7 0.0 1.6 8.4 0.0 4.0 3 0 0 3 3 3 1 IstB-like ATP binding protein RsgA_GTPase PF03193.16 CBK23139.2 - 0.00086 19.2 1.7 0.95 9.3 0.0 4.1 4 0 0 4 4 3 1 RsgA GTPase Zeta_toxin PF06414.12 CBK23139.2 - 0.001 18.4 0.0 3.2 7.0 0.0 3.8 3 0 0 3 3 3 1 Zeta toxin AAA_21 PF13304.6 CBK23139.2 - 0.0026 17.6 0.0 0.089 12.6 0.0 3.2 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_25 PF13481.6 CBK23139.2 - 0.0034 17.0 0.0 1.2 8.7 0.0 4.0 4 0 0 4 4 3 1 AAA domain Roc PF08477.13 CBK23139.2 - 0.007 16.6 0.4 12 6.1 0.0 4.0 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase Guanylate_kin PF00625.21 CBK23139.2 - 0.0098 15.6 1.1 5.4 6.7 0.0 3.6 3 0 0 3 3 3 0 Guanylate kinase ABC_tran PF00005.27 CBK23139.2 - 0.011 16.3 0.0 0.011 16.3 0.0 5.8 7 0 0 7 7 3 0 ABC transporter RuvB_N PF05496.12 CBK23139.2 - 0.012 15.4 0.0 3.1 7.5 0.0 3.3 3 0 0 3 3 3 0 Holliday junction DNA helicase RuvB P-loop domain cobW PF02492.19 CBK23139.2 - 0.012 15.2 0.8 2.8 7.5 0.0 3.1 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain AAA_lid_1 PF17857.1 CBK23139.2 - 0.052 13.8 0.0 0.34 11.1 0.0 2.5 1 0 0 1 1 1 0 AAA+ lid domain AAA_28 PF13521.6 CBK23139.2 - 0.057 13.7 0.1 91 3.2 0.0 4.9 5 0 0 5 5 4 0 AAA domain PHtD_u1 PF16645.5 CBK23139.2 - 0.068 13.6 0.4 0.33 11.4 0.4 2.2 1 0 0 1 1 1 0 Unstructured region on Pneumococcal histidine triad protein AAA_23 PF13476.6 CBK23139.2 - 0.99 9.9 0.0 0.99 9.9 0.0 8.4 6 1 0 6 6 4 0 AAA domain Spt5_N PF11942.8 CBK23139.2 - 2 9.4 5.3 8.2 7.5 5.3 2.0 1 0 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal OCRE PF17780.1 CBK23140.2 - 1.7e-06 27.9 2.5 3.2e-06 27.1 2.5 1.4 1 0 0 1 1 1 1 OCRE domain STD1 PF17235.2 CBK23142.2 - 0.024 14.3 0.0 0.024 14.3 0.0 1.1 1 0 0 1 1 1 0 STD1/MTH1 HSP70 PF00012.20 CBK23143.2 - 1.1e-104 350.8 13.0 6e-104 348.4 10.3 3.0 2 1 0 2 2 2 1 Hsp70 protein MreB_Mbl PF06723.13 CBK23143.2 - 0.012 14.4 0.0 0.026 13.3 0.0 1.5 1 0 0 1 1 1 0 MreB/Mbl protein DFRP_C PF16543.5 CBK23144.2 - 5.7e-17 62.0 9.4 5.7e-17 62.0 9.4 4.6 3 2 1 4 4 4 1 DRG Family Regulatory Proteins, Tma46 zf_CCCH_4 PF18345.1 CBK23144.2 - 2.9e-07 30.3 17.9 5.1e-06 26.4 5.3 3.0 3 0 0 3 3 3 2 Zinc finger domain zf-CCCH_4 PF18044.1 CBK23144.2 - 4.7e-07 29.4 14.2 2.2e-06 27.3 3.2 3.1 3 0 0 3 3 3 2 CCCH-type zinc finger zf-CCCH PF00642.24 CBK23144.2 - 6.4e-07 29.1 8.3 1.1e-05 25.2 1.1 2.7 3 0 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 CBK23144.2 - 7.6e-06 26.6 17.3 0.00089 19.9 5.0 4.1 2 1 1 3 3 3 2 Torus domain zf-CCCH_3 PF15663.5 CBK23144.2 - 0.006 16.8 4.9 0.44 10.8 0.1 2.9 3 0 0 3 3 3 2 Zinc-finger containing family zf-CCCH_2 PF14608.6 CBK23144.2 - 0.014 15.8 12.1 0.79 10.3 1.3 2.9 2 1 0 2 2 2 0 RNA-binding, Nab2-type zinc finger PRORP PF16953.5 CBK23145.2 - 1.2e-37 129.7 2.0 1.5e-37 129.5 2.0 1.1 1 0 0 1 1 1 1 Protein-only RNase P RNase_Zc3h12a PF11977.8 CBK23145.2 - 1.2e-08 34.9 1.5 1.8e-07 31.1 1.5 2.2 1 1 0 1 1 1 1 Zc3h12a-like Ribonuclease NYN domain DUF2543 PF10820.8 CBK23145.2 - 0.016 15.4 0.0 6.5 7.0 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2543) LSM PF01423.22 CBK23146.2 - 3.5e-07 29.8 0.2 4e-07 29.6 0.2 1.1 1 0 0 1 1 1 1 LSM domain HSP70 PF00012.20 CBK23147.2 - 3.3e-78 263.4 0.3 4.2e-78 263.0 0.3 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 CBK23147.2 - 5e-14 51.9 4.1 5.7e-10 38.5 0.8 3.1 3 0 0 3 3 3 3 MreB/Mbl protein FtsA PF14450.6 CBK23147.2 - 3.4e-05 24.2 0.1 0.022 15.1 0.0 2.8 2 1 0 2 2 2 2 Cell division protein FtsA Hydantoinase_A PF01968.18 CBK23147.2 - 0.00019 20.8 3.3 0.0038 16.5 0.0 2.8 3 0 0 3 3 3 2 Hydantoinase/oxoprolinase StbA PF06406.11 CBK23147.2 - 0.0034 16.7 0.2 0.018 14.3 0.0 2.0 2 0 0 2 2 2 1 StbA protein Beach PF02138.18 CBK23148.2 - 1.3e-108 362.6 1.5 1.9e-108 362.0 1.5 1.3 1 0 0 1 1 1 1 Beige/BEACH domain PH_BEACH PF14844.6 CBK23148.2 - 4.5e-26 90.9 0.7 1.7e-25 89.1 0.7 2.1 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH WD40 PF00400.32 CBK23148.2 - 2.8e-12 47.0 1.0 0.00037 21.2 0.1 5.1 5 0 0 5 5 5 2 WD domain, G-beta repeat DUF4800 PF16057.5 CBK23148.2 - 0.00037 19.9 0.2 0.00078 18.8 0.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4800) ANAPC4_WD40 PF12894.7 CBK23148.2 - 0.0032 17.8 0.0 13 6.1 0.0 3.8 2 1 3 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 CBK23148.2 - 0.0061 15.9 0.2 0.0061 15.9 0.2 2.0 2 0 0 2 2 2 1 WD40-like domain Alpha-E PF04168.12 CBK23148.2 - 0.045 13.5 0.0 0.093 12.5 0.0 1.4 1 0 0 1 1 1 0 A predicted alpha-helical domain with a conserved ER motif. DUF4704 PF15787.5 CBK23149.2 - 8.4e-38 130.2 0.4 8.4e-38 130.2 0.4 2.9 3 0 0 3 3 3 1 Domain of unknown function (DUF4704) Laminin_G_3 PF13385.6 CBK23149.2 - 1.8e-07 31.4 0.0 3.7e-07 30.4 0.0 1.5 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily Lipase_3 PF01764.25 CBK23150.2 - 3.7e-17 62.5 0.0 5.3e-17 62.0 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 CBK23150.2 - 0.006 17.2 0.0 0.011 16.4 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 CBK23150.2 - 0.013 14.8 0.0 0.022 14.0 0.0 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 PGAP1 PF07819.13 CBK23150.2 - 0.036 13.8 0.0 0.052 13.3 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein Abhydrolase_3 PF07859.13 CBK23150.2 - 0.041 13.8 0.0 0.061 13.2 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold Cutinase PF01083.22 CBK23150.2 - 0.13 12.2 0.0 0.23 11.4 0.0 1.4 1 0 0 1 1 1 0 Cutinase Adap_comp_sub PF00928.21 CBK23151.2 - 1.9e-84 283.1 0.0 2.4e-84 282.8 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 CBK23151.2 - 0.00015 21.7 4.0 0.00022 21.1 3.6 1.5 1 1 0 1 1 1 1 Clathrin adaptor complex small chain LRR_4 PF12799.7 CBK23152.2 - 3.8e-05 23.9 0.9 0.3 11.6 0.1 4.1 2 1 0 3 3 3 2 Leucine Rich repeats (2 copies) Cep57_CLD_2 PF14197.6 CBK23152.2 - 0.00025 21.1 11.5 0.00025 21.1 11.5 8.9 6 3 1 7 7 6 2 Centrosome localisation domain of PPC89 LRR_1 PF00560.33 CBK23152.2 - 0.00037 20.7 0.5 1.9 9.4 0.0 4.7 4 0 0 4 4 4 1 Leucine Rich Repeat LRR_8 PF13855.6 CBK23152.2 - 0.0041 16.8 2.5 0.33 10.7 0.1 4.1 4 0 0 4 4 4 1 Leucine rich repeat Csm1_N PF18504.1 CBK23152.2 - 0.0042 17.4 2.8 0.0042 17.4 2.8 11.6 5 3 6 12 12 12 2 Csm1 N-terminal domain Fez1 PF06818.15 CBK23152.2 - 0.0055 17.2 20.7 0.0055 17.2 20.7 5.6 2 2 2 4 4 4 2 Fez1 LRR_6 PF13516.6 CBK23152.2 - 0.0067 16.4 4.4 0.37 11.0 0.3 4.3 5 0 0 5 5 5 1 Leucine Rich repeat CEP63 PF17045.5 CBK23152.2 - 0.0087 16.0 6.0 0.0087 16.0 6.0 5.6 3 1 3 6 6 5 1 Centrosomal protein of 63 kDa SOGA PF11365.8 CBK23152.2 - 0.011 16.9 9.5 0.011 16.9 9.5 8.1 2 2 5 7 7 6 0 Protein SOGA CENP-Q PF13094.6 CBK23152.2 - 0.016 15.4 5.1 0.016 15.4 5.1 7.3 2 2 3 5 5 3 0 CENP-Q, a CENPA-CAD centromere complex subunit TPR_MLP1_2 PF07926.12 CBK23152.2 - 0.018 15.1 111.8 0.02 15.0 11.2 8.6 2 2 5 8 8 7 0 TPR/MLP1/MLP2-like protein MAD PF05557.13 CBK23152.2 - 0.027 12.8 97.8 0.0042 15.5 32.9 3.2 2 1 1 3 3 3 0 Mitotic checkpoint protein Uso1_p115_C PF04871.13 CBK23152.2 - 0.1 13.0 96.1 1.3 9.4 10.0 7.3 2 2 4 6 6 6 0 Uso1 / p115 like vesicle tethering protein, C terminal region Spc7 PF08317.11 CBK23152.2 - 1.4 7.7 106.6 0.017 14.1 16.3 5.2 2 2 2 5 5 5 0 Spc7 kinetochore protein CALCOCO1 PF07888.11 CBK23152.2 - 3.8 6.3 97.7 0.23 10.3 24.1 3.6 2 1 1 3 3 3 0 Calcium binding and coiled-coil domain (CALCOCO1) like GAS PF13851.6 CBK23152.2 - 5.1 6.4 106.0 0.035 13.5 21.2 5.8 2 2 2 5 5 5 0 Growth-arrest specific micro-tubule binding APG6_N PF17675.1 CBK23152.2 - 6.2 7.4 119.2 0.17 12.4 26.9 7.3 2 2 4 7 7 7 0 Apg6 coiled-coil region RRM_1 PF00076.22 CBK23153.2 - 1.5e-11 43.9 0.0 2.5e-11 43.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Surp PF01805.20 CBK23153.2 - 6.3e-07 29.3 0.0 1.5e-06 28.1 0.0 1.6 1 0 0 1 1 1 1 Surp module RRM_5 PF13893.6 CBK23153.2 - 0.0005 19.7 0.0 0.00081 19.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PagP PF07017.11 CBK23153.2 - 0.02 14.3 0.1 0.035 13.5 0.1 1.3 1 0 0 1 1 1 0 Antimicrobial peptide resistance and lipid A acylation protein PagP GAGA PF09237.11 CBK23154.2 - 0.16 11.8 1.8 0.21 11.4 0.9 1.7 1 1 1 2 2 2 0 GAGA factor LRR_6 PF13516.6 CBK23155.2 - 3.4e-18 64.1 22.2 0.00046 20.0 0.2 8.1 9 0 0 9 9 9 5 Leucine Rich repeat LRR_4 PF12799.7 CBK23155.2 - 3.3e-10 40.1 14.7 0.0058 17.0 0.1 6.4 4 2 1 5 5 5 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CBK23155.2 - 1.5e-08 34.3 17.9 0.024 14.4 0.1 7.4 5 3 0 6 6 6 3 Leucine rich repeat LRR_1 PF00560.33 CBK23155.2 - 0.0023 18.2 29.9 4.9 8.1 0.1 8.8 8 1 0 8 8 8 4 Leucine Rich Repeat HSP70 PF00012.20 CBK23156.2 - 6.2e-150 500.3 0.1 6.8e-150 500.1 0.1 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 CBK23156.2 - 6e-18 64.7 0.0 2.4e-15 56.2 0.0 2.2 2 0 0 2 2 2 2 MreB/Mbl protein DDR PF08841.10 CBK23156.2 - 0.00089 18.3 0.3 1.8 7.5 0.0 3.0 3 0 0 3 3 3 2 Diol dehydratase reactivase ATPase-like domain DUF1464 PF07318.12 CBK23156.2 - 0.0029 16.8 0.0 0.0069 15.6 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1464) FtsA PF14450.6 CBK23156.2 - 0.0076 16.6 1.1 1.1 9.7 0.0 3.1 2 2 0 2 2 2 1 Cell division protein FtsA FGGY_C PF02782.16 CBK23156.2 - 0.036 13.8 0.0 0.08 12.7 0.0 1.6 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain MM_CoA_mutase PF01642.22 CBK23157.2 - 2.1e-231 768.9 1.3 2.6e-231 768.6 1.3 1.1 1 0 0 1 1 1 1 Methylmalonyl-CoA mutase B12-binding PF02310.19 CBK23157.2 - 4.7e-12 46.0 0.2 1.1e-11 44.8 0.2 1.6 1 0 0 1 1 1 1 B12 binding domain IMPDH PF00478.25 CBK23157.2 - 0.0033 16.5 0.0 0.0051 15.9 0.0 1.4 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain PhnI PF05861.12 CBK23157.2 - 0.051 12.4 0.0 0.095 11.5 0.0 1.3 1 0 0 1 1 1 0 Bacterial phosphonate metabolism protein (PhnI) DUF4729 PF15866.5 CBK23159.2 - 0.071 12.4 0.7 0.084 12.2 0.7 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4729) Zip PF02535.22 CBK23159.2 - 0.93 8.6 11.3 0.99 8.6 11.3 1.0 1 0 0 1 1 1 0 ZIP Zinc transporter Pox_Ag35 PF03286.14 CBK23159.2 - 1.1 9.0 18.3 1.5 8.6 18.3 1.1 1 0 0 1 1 1 0 Pox virus Ag35 surface protein RR_TM4-6 PF06459.12 CBK23159.2 - 1.7 8.4 15.0 1.7 8.4 15.0 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Paf1 PF03985.13 CBK23159.2 - 2.6 6.9 23.4 2.9 6.8 23.4 1.1 1 0 0 1 1 1 0 Paf1 Presenilin PF01080.17 CBK23159.2 - 2.7 6.6 16.0 2.8 6.6 16.0 1.0 1 0 0 1 1 1 0 Presenilin FAM60A PF15396.6 CBK23159.2 - 3.1 7.7 11.3 3.4 7.6 11.3 1.1 1 0 0 1 1 1 0 Protein Family FAM60A Neur_chan_memb PF02932.16 CBK23159.2 - 5 7.1 7.1 5.3 7.0 7.1 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region SAPS PF04499.15 CBK23159.2 - 9.1 4.9 16.9 9.7 4.8 16.9 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein He_PIG PF05345.12 CBK23160.2 - 4.7e-14 52.3 14.3 0.00023 21.3 1.8 5.1 4 0 0 4 4 4 3 Putative Ig domain Shisa PF13908.6 CBK23160.2 - 0.02 15.1 1.8 0.041 14.1 1.8 1.5 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator EphA2_TM PF14575.6 CBK23160.2 - 0.049 14.5 3.4 0.11 13.4 3.4 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Baculo_11_kDa PF06143.11 CBK23160.2 - 0.079 12.5 5.6 0.19 11.3 5.6 1.5 1 0 0 1 1 1 0 Baculovirus 11 kDa family PIF6 PF05341.11 CBK23160.2 - 0.087 13.0 0.1 0.54 10.4 0.0 2.4 2 0 0 2 2 2 0 Per os infectivity factor 6 Orf78 PF06024.12 CBK23160.2 - 0.088 13.1 0.4 0.19 12.1 0.4 1.5 1 0 0 1 1 1 0 Orf78 (ac78) SCIMP PF15050.6 CBK23160.2 - 0.092 13.2 3.0 0.26 11.7 3.0 1.7 1 0 0 1 1 1 0 SCIMP protein Orthoreo_P10 PF07204.11 CBK23160.2 - 0.12 12.3 0.7 0.31 11.0 0.7 1.6 1 0 0 1 1 1 0 Orthoreovirus membrane fusion protein p10 LRRC37AB_C PF14914.6 CBK23160.2 - 0.14 12.0 1.9 0.29 11.0 1.9 1.4 1 0 0 1 1 1 0 LRRC37A/B like protein 1 C-terminal domain ECSCR PF15820.5 CBK23160.2 - 0.3 10.9 6.8 1 9.2 6.8 1.9 1 0 0 1 1 1 0 Endothelial cell-specific chemotaxis regulator DUF4834 PF16118.5 CBK23160.2 - 0.55 11.2 2.2 1.3 10.0 2.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) SP_C-Propep PF08999.10 CBK23160.2 - 0.68 9.7 5.1 1.4 8.7 5.1 1.4 1 0 0 1 1 1 0 Surfactant protein C, N terminal propeptide TMEM154 PF15102.6 CBK23160.2 - 2 8.3 10.3 0.046 13.6 2.5 2.1 2 0 0 2 2 2 0 TMEM154 protein family Vasculin PF15337.6 CBK23162.2 - 0.3 11.9 5.4 0.57 11.0 5.4 1.5 1 1 0 1 1 1 0 Vascular protein family Vasculin-like 1 GST_C_3 PF14497.6 CBK23163.2 - 9e-10 38.6 0.1 1.2e-09 38.2 0.1 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 CBK23163.2 - 0.00075 19.7 0.0 0.0011 19.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 CBK23163.2 - 0.013 15.5 0.0 0.019 15.0 0.0 1.5 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain DUF3546 PF12066.8 CBK23165.2 - 1.5e-05 25.2 2.6 1.6e-05 25.1 0.7 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF3546) zf-C2H2 PF00096.26 CBK23165.2 - 0.00011 22.4 0.1 0.00011 22.4 0.1 2.2 2 0 0 2 2 1 1 Zinc finger, C2H2 type ARS2 PF04959.13 CBK23165.2 - 0.0002 21.8 4.7 0.00023 21.6 2.7 1.9 2 0 0 2 2 2 1 Arsenite-resistance protein 2 zf-C2H2_2 PF12756.7 CBK23165.2 - 0.00025 21.3 2.8 0.0037 17.6 0.3 2.7 2 1 0 3 3 3 1 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.8 CBK23165.2 - 0.00025 21.2 0.8 0.00025 21.2 0.8 2.7 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding DUF629 PF04780.12 CBK23165.2 - 0.0012 17.4 0.2 0.002 16.8 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF629) zf-C2H2_4 PF13894.6 CBK23165.2 - 0.0019 18.9 0.1 0.0019 18.9 0.1 2.5 2 0 0 2 2 1 1 C2H2-type zinc finger zf-C2H2_6 PF13912.6 CBK23165.2 - 0.011 15.7 0.1 0.03 14.3 0.1 1.7 1 0 0 1 1 1 0 C2H2-type zinc finger RRM_1 PF00076.22 CBK23165.2 - 0.019 14.8 0.0 1 9.2 0.0 3.0 3 1 0 3 3 3 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-met PF12874.7 CBK23165.2 - 0.15 12.5 0.1 0.15 12.5 0.1 2.1 2 0 0 2 2 2 0 Zinc-finger of C2H2 type PP2C_C PF07830.13 CBK23165.2 - 0.55 10.7 3.3 11 6.6 0.3 3.3 2 1 1 3 3 3 0 Protein serine/threonine phosphatase 2C, C-terminal domain SPC25 PF06703.11 CBK23166.2 - 2.4e-17 63.2 0.3 3.1e-17 62.9 0.3 1.1 1 0 0 1 1 1 1 Microsomal signal peptidase 25 kDa subunit (SPC25) UCR_14kD PF02271.16 CBK23166.2 - 0.12 12.4 0.0 0.2 11.6 0.0 1.3 1 0 0 1 1 1 0 Ubiquinol-cytochrome C reductase complex 14kD subunit ADH_N PF08240.12 CBK23167.2 - 5.2e-09 36.0 0.2 2.3e-06 27.4 0.0 3.2 2 1 1 3 3 3 2 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 CBK23167.2 - 2.2e-05 24.4 0.1 3.7e-05 23.7 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase KH_1 PF00013.29 CBK23169.2 - 1.4e-11 44.1 0.1 2e-11 43.5 0.1 1.3 1 0 0 1 1 1 1 KH domain ATP_synt_H PF05493.13 CBK23170.2 - 3.4e-22 78.7 6.9 4.2e-22 78.4 6.9 1.1 1 0 0 1 1 1 1 ATP synthase subunit H DUF4491 PF14898.6 CBK23170.2 - 0.05 14.1 4.0 0.056 13.9 4.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4491) DUF1345 PF07077.11 CBK23170.2 - 0.2 11.4 3.0 0.23 11.1 3.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1345) DUF3810 PF12725.7 CBK23170.2 - 0.28 10.5 1.5 0.31 10.4 1.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) Shisa PF13908.6 CBK23170.2 - 1.1 9.4 5.2 0.54 10.5 0.7 1.9 1 1 1 2 2 2 0 Wnt and FGF inhibitory regulator B12D PF06522.11 CBK23170.2 - 4.9 7.0 5.3 14 5.6 0.5 2.1 2 0 0 2 2 2 0 NADH-ubiquinone reductase complex 1 MLRQ subunit Caveolin PF01146.17 CBK23170.2 - 6.6 6.7 8.1 1.1 9.2 3.2 1.8 1 1 1 2 2 2 0 Caveolin Tmemb_9 PF05434.11 CBK23170.2 - 9.9 6.0 6.8 1.7 8.5 2.4 1.7 1 1 1 2 2 2 0 TMEM9 MgsA_C PF12002.8 CBK23172.2 - 3e-55 186.7 0.1 4.6e-55 186.1 0.1 1.3 1 0 0 1 1 1 1 MgsA AAA+ ATPase C terminal AAA_assoc_2 PF16193.5 CBK23172.2 - 1.1e-19 70.5 0.1 2.5e-19 69.4 0.1 1.6 1 0 0 1 1 1 1 AAA C-terminal domain AAA PF00004.29 CBK23172.2 - 3e-06 27.7 0.0 1.2e-05 25.7 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 CBK23172.2 - 0.0046 16.7 0.0 0.0092 15.7 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain Sigma54_activat PF00158.26 CBK23172.2 - 0.023 14.4 0.0 0.043 13.5 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain DNA_pol3_delta2 PF13177.6 CBK23172.2 - 0.1 12.4 0.1 0.47 10.2 0.1 1.9 2 0 0 2 2 2 0 DNA polymerase III, delta subunit FapA PF03961.13 CBK23173.2 - 3.8e-05 22.5 6.7 4.3e-05 22.3 6.7 1.0 1 0 0 1 1 1 1 Flagellar Assembly Protein A CLZ PF16526.5 CBK23173.2 - 0.00084 19.6 4.5 0.0022 18.3 4.2 1.8 1 1 0 1 1 1 1 C-terminal leucine zipper domain of cyclic nucleotide-gated channels HemX PF04375.14 CBK23173.2 - 0.0037 16.6 0.2 0.0051 16.1 0.2 1.1 1 0 0 1 1 1 1 HemX, putative uroporphyrinogen-III C-methyltransferase Helo_like_N PF17111.5 CBK23173.2 - 0.0053 16.1 1.7 0.0078 15.6 1.4 1.4 1 1 0 1 1 1 1 Fungal N-terminal domain of STAND proteins ABC_tran_CTD PF16326.5 CBK23173.2 - 0.0061 16.8 5.7 0.0075 16.5 4.2 1.9 1 1 1 2 2 2 1 ABC transporter C-terminal domain Atg14 PF10186.9 CBK23173.2 - 0.0079 15.3 1.9 0.009 15.1 1.9 1.2 1 0 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 Bacillus_HBL PF05791.11 CBK23173.2 - 0.0091 15.8 5.7 0.012 15.4 5.7 1.2 1 0 0 1 1 1 1 Bacillus haemolytic enterotoxin (HBL) DUF4446 PF14584.6 CBK23173.2 - 0.0094 15.9 2.4 0.0094 15.9 2.4 2.1 1 1 1 2 2 2 1 Protein of unknown function (DUF4446) Polyoma_lg_T_C PF06431.11 CBK23173.2 - 0.0095 14.8 2.1 0.012 14.6 1.8 1.3 1 1 0 1 1 1 1 Polyomavirus large T antigen C-terminus JAKMIP_CC3 PF16034.5 CBK23173.2 - 0.014 15.4 6.5 0.018 15.0 6.5 1.1 1 0 0 1 1 1 0 JAKMIP CC3 domain Baculo_PEP_C PF04513.12 CBK23173.2 - 0.015 15.4 0.8 0.04 13.9 0.5 1.6 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Fmp27_WPPW PF10359.9 CBK23173.2 - 0.015 14.1 5.5 0.017 14.0 5.5 1.1 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain DUF4988 PF16378.5 CBK23173.2 - 0.016 14.9 4.0 0.67 9.6 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function DUF1664 PF07889.12 CBK23173.2 - 0.018 15.0 7.9 0.19 11.7 2.9 2.3 1 1 0 2 2 2 0 Protein of unknown function (DUF1664) SYCE1 PF15233.6 CBK23173.2 - 0.023 14.8 9.3 0.41 10.7 0.3 2.1 1 1 1 2 2 2 0 Synaptonemal complex central element protein 1 DUF1465 PF07323.12 CBK23173.2 - 0.034 14.0 1.1 0.097 12.5 1.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1465) IES5 PF17335.2 CBK23173.2 - 0.035 14.4 6.7 0.19 12.0 7.2 1.8 1 1 1 2 2 2 0 Ino80 complex subunit 5 TolA_bind_tri PF16331.5 CBK23173.2 - 0.036 14.2 1.8 0.088 12.9 1.4 1.8 1 1 1 2 2 2 0 TolA binding protein trimerisation Rx_N PF18052.1 CBK23173.2 - 0.04 14.2 2.4 0.068 13.5 2.4 1.4 1 0 0 1 1 1 0 Rx N-terminal domain DUF3450 PF11932.8 CBK23173.2 - 0.041 13.2 3.9 0.065 12.5 3.9 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3450) HOOK PF05622.12 CBK23173.2 - 0.052 11.7 8.6 0.065 11.4 8.6 1.1 1 0 0 1 1 1 0 HOOK protein Ax_dynein_light PF10211.9 CBK23173.2 - 0.077 12.9 6.9 0.12 12.3 6.9 1.3 1 0 0 1 1 1 0 Axonemal dynein light chain EMP24_GP25L PF01105.24 CBK23173.2 - 0.089 12.7 5.2 0.13 12.2 4.7 1.6 1 1 0 1 1 1 0 emp24/gp25L/p24 family/GOLD DUF1192 PF06698.11 CBK23173.2 - 0.093 12.8 3.1 2.9 8.0 0.9 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF1192) ISG65-75 PF11727.8 CBK23173.2 - 0.094 11.9 3.9 0.12 11.6 3.9 1.1 1 0 0 1 1 1 0 Invariant surface glycoprotein RPW8 PF05659.11 CBK23173.2 - 0.095 12.4 6.7 0.14 11.9 5.4 1.9 1 1 0 2 2 2 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 Fzo_mitofusin PF04799.13 CBK23173.2 - 0.1 12.2 4.5 0.16 11.5 1.4 2.1 1 1 1 2 2 2 0 fzo-like conserved region E2F_CC-MB PF16421.5 CBK23173.2 - 0.1 13.0 3.0 0.2 12.0 2.9 1.6 1 1 0 1 1 1 0 E2F transcription factor CC-MB domain Tweety PF04906.13 CBK23173.2 - 0.11 11.2 1.5 0.098 11.3 0.7 1.5 1 1 1 2 2 2 0 Tweety DivIC PF04977.15 CBK23173.2 - 0.12 12.1 9.0 0.13 12.0 2.9 2.7 1 1 3 4 4 4 0 Septum formation initiator CYTL1 PF15153.6 CBK23173.2 - 0.12 12.3 1.8 0.68 9.9 0.7 2.1 2 0 0 2 2 2 0 Cytokine-like protein 1 FlxA PF14282.6 CBK23173.2 - 0.15 12.0 6.2 0.25 11.3 6.2 1.3 1 0 0 1 1 1 0 FlxA-like protein SlyX PF04102.12 CBK23173.2 - 0.15 12.7 3.2 2.7 8.7 0.7 2.3 1 1 1 2 2 2 0 SlyX Allexi_40kDa PF05549.11 CBK23173.2 - 0.19 11.2 1.8 0.26 10.7 1.8 1.3 1 0 0 1 1 1 0 Allexivirus 40kDa protein Sugar_tr PF00083.24 CBK23173.2 - 0.2 10.5 3.3 0.26 10.1 0.3 2.0 1 1 1 2 2 2 0 Sugar (and other) transporter COG5 PF10392.9 CBK23173.2 - 0.24 11.6 4.8 1.5 9.0 0.3 2.1 1 1 1 2 2 2 0 Golgi transport complex subunit 5 PCRF PF03462.18 CBK23173.2 - 0.26 11.1 3.6 0.37 10.6 3.6 1.3 1 0 0 1 1 1 0 PCRF domain HAUS5 PF14817.6 CBK23173.2 - 0.29 9.9 4.5 0.87 8.3 2.1 1.6 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 5 YojJ PF10372.9 CBK23173.2 - 0.31 11.2 3.4 0.76 9.9 3.0 2.0 1 1 0 1 1 1 0 Bacterial membrane-spanning protein N-terminus DUF2203 PF09969.9 CBK23173.2 - 0.35 11.6 2.9 0.68 10.7 2.8 1.7 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) CENP-Q PF13094.6 CBK23173.2 - 0.36 11.0 4.7 13 6.0 0.1 2.1 1 1 1 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit BLOC1_2 PF10046.9 CBK23173.2 - 0.36 11.2 11.5 0.11 12.8 4.9 2.4 2 1 1 3 3 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 HAUS6_N PF14661.6 CBK23173.2 - 0.4 10.2 4.1 0.59 9.7 4.1 1.3 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus GrpE PF01025.19 CBK23173.2 - 0.51 10.0 9.1 0.77 9.4 1.3 2.1 1 1 1 2 2 2 0 GrpE APG6_N PF17675.1 CBK23173.2 - 0.53 10.8 9.6 2.1 8.8 8.1 2.0 1 1 1 2 2 2 0 Apg6 coiled-coil region Spc24 PF08286.11 CBK23173.2 - 0.56 10.5 7.0 0.88 9.8 7.0 1.3 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 Seryl_tRNA_N PF02403.22 CBK23173.2 - 0.6 10.4 11.9 2.9 8.1 4.4 2.1 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain BST2 PF16716.5 CBK23173.2 - 0.69 10.5 5.8 1.9 9.1 1.9 2.2 1 1 1 2 2 2 0 Bone marrow stromal antigen 2 HMMR_N PF15905.5 CBK23173.2 - 0.73 9.2 12.8 3.4 7.0 6.2 2.0 1 1 1 2 2 2 0 Hyaluronan mediated motility receptor N-terminal Prefoldin_2 PF01920.20 CBK23173.2 - 0.74 9.8 12.3 2.5 8.1 5.4 2.5 1 1 1 2 2 2 0 Prefoldin subunit FlaC_arch PF05377.11 CBK23173.2 - 0.79 10.2 11.3 1.4 9.3 0.6 3.0 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) DUF16 PF01519.16 CBK23173.2 - 0.83 10.2 8.9 8.4 6.9 7.8 2.2 1 1 1 2 2 2 0 Protein of unknown function DUF16 zf-C4H2 PF10146.9 CBK23173.2 - 0.83 9.9 6.9 1.3 9.3 6.9 1.3 1 0 0 1 1 1 0 Zinc finger-containing protein V-SNARE PF05008.15 CBK23173.2 - 1.1 9.7 9.7 7.5 7.0 8.1 2.3 1 1 1 2 2 2 0 Vesicle transport v-SNARE protein N-terminus DUF5082 PF16888.5 CBK23173.2 - 1.1 9.6 10.9 4.9 7.4 3.4 2.4 1 1 0 2 2 2 0 Domain of unknown function (DUF5082) HIP1_clath_bdg PF16515.5 CBK23173.2 - 1.1 9.9 6.1 2.7 8.6 6.1 1.6 1 1 0 1 1 1 0 Clathrin-binding domain of Huntingtin-interacting protein 1 DUF4140 PF13600.6 CBK23173.2 - 1.2 9.6 3.8 4.9 7.7 1.4 2.1 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) bZIP_1 PF00170.21 CBK23173.2 - 2.2 8.5 7.7 1.4e+02 2.7 7.7 2.5 1 1 0 1 1 1 0 bZIP transcription factor Fib_alpha PF08702.10 CBK23173.2 - 2.8 8.1 9.9 6.4 7.0 2.5 1.9 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family MRPL52 PF18699.1 CBK23173.2 - 4.5 7.5 8.1 8.1 6.7 4.1 2.2 1 1 2 3 3 3 0 Mitoribosomal protein mL52 XhlA PF10779.9 CBK23173.2 - 6.3 7.1 13.7 10 6.4 0.7 2.5 2 0 0 2 2 2 0 Haemolysin XhlA TSC22 PF01166.18 CBK23173.2 - 6.7 7.1 8.6 2.6 8.4 0.2 2.7 2 1 0 2 2 2 0 TSC-22/dip/bun family RsgA_GTPase PF03193.16 CBK23174.2 - 3.8e-05 23.7 0.2 7e-05 22.8 0.2 1.5 1 1 0 1 1 1 1 RsgA GTPase MMR_HSR1 PF01926.23 CBK23174.2 - 0.00027 21.0 0.0 0.0015 18.6 0.0 2.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 CBK23174.2 - 0.048 13.2 0.1 0.47 10.0 0.0 2.0 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_18 PF13238.6 CBK23174.2 - 0.1 13.1 0.0 0.25 11.9 0.0 1.6 2 0 0 2 2 2 0 AAA domain fn3 PF00041.21 CBK23175.2 - 3.1e-09 37.0 0.1 0.00017 21.8 0.0 4.8 6 0 0 6 6 6 2 Fibronectin type III domain Big_5 PF13205.6 CBK23175.2 - 1.2e-08 35.6 0.1 9.9e-07 29.4 0.0 3.4 3 0 0 3 3 3 1 Bacterial Ig-like domain HRM PF02793.22 CBK23175.2 - 5.4e-07 29.8 157.9 0.00015 21.9 0.5 22.3 10 4 10 20 20 20 7 Hormone receptor domain Pur_ac_phosph_N PF16656.5 CBK23175.2 - 0.00025 21.6 2.1 1.5 9.4 0.1 4.5 4 1 0 4 4 4 2 Purple acid Phosphatase, N-terminal domain CNH PF00780.22 CBK23177.2 - 1e-20 74.5 0.0 1.7e-20 73.8 0.0 1.3 1 0 0 1 1 1 1 CNH domain HPS3_N PF14761.6 CBK23177.2 - 0.044 13.3 1.5 0.17 11.4 0.0 2.7 3 1 1 4 4 4 0 Hermansky-Pudlak syndrome 3 TPR_1 PF00515.28 CBK23177.2 - 0.19 11.6 0.7 0.66 9.9 0.1 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat Vps39_2 PF10367.9 CBK23178.2 - 5.7e-21 75.0 1.2 1.9e-20 73.3 0.0 2.3 3 0 0 3 3 3 1 Vacuolar sorting protein 39 domain 2 Clathrin PF00637.20 CBK23178.2 - 0.00018 21.4 3.5 0.00035 20.5 0.3 2.5 3 0 0 3 3 3 1 Region in Clathrin and VPS Cwf_Cwc_15 PF04889.12 CBK23179.2 - 5e-38 131.2 24.0 3.5e-36 125.2 24.0 2.0 1 1 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein RD3 PF14473.6 CBK23179.2 - 0.011 15.6 1.5 0.021 14.7 1.5 1.4 1 0 0 1 1 1 0 RD3 protein Hid1 PF12722.7 CBK23179.2 - 0.037 12.2 3.9 0.044 11.9 3.9 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein YL1 PF05764.13 CBK23179.2 - 0.17 12.0 14.0 0.22 11.6 14.0 1.2 1 0 0 1 1 1 0 YL1 nuclear protein CDC45 PF02724.14 CBK23179.2 - 8.5 4.5 11.0 9.3 4.4 11.0 1.1 1 0 0 1 1 1 0 CDC45-like protein GATase_6 PF13522.6 CBK23180.2 - 1.1e-12 48.3 0.0 4.9e-12 46.2 0.0 2.0 1 1 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.6 CBK23180.2 - 7.7e-11 42.0 0.0 2.4e-10 40.4 0.0 1.8 1 1 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.6 CBK23180.2 - 5e-05 22.3 0.0 7.2e-05 21.8 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Pribosyltran PF00156.27 CBK23180.2 - 0.0025 17.3 0.0 0.0042 16.6 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain GATase_2 PF00310.21 CBK23180.2 - 0.0028 16.4 0.1 0.22 10.2 0.0 2.5 2 1 1 3 3 3 2 Glutamine amidotransferases class-II Adap_comp_sub PF00928.21 CBK23181.2 - 2.4e-81 273.0 0.0 3e-81 272.7 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 CBK23181.2 - 3.5e-09 36.7 0.2 6.3e-09 35.9 0.2 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain muHD PF10291.9 CBK23181.2 - 0.0028 17.2 0.0 0.0044 16.5 0.0 1.3 1 0 0 1 1 1 1 Muniscin C-terminal mu homology domain Longin PF13774.6 CBK23181.2 - 0.062 13.4 0.1 0.14 12.2 0.1 1.6 1 0 0 1 1 1 0 Regulated-SNARE-like domain S_100 PF01023.19 CBK23182.2 - 0.0088 15.7 0.3 0.068 12.9 0.0 2.2 2 0 0 2 2 2 1 S-100/ICaBP type calcium binding domain Pro_isomerase PF00160.21 CBK23183.2 - 8.6e-44 149.6 0.1 9.6e-44 149.4 0.1 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD PDZ_6 PF17820.1 CBK23184.2 - 1.4e-06 28.0 0.0 2.9e-06 27.0 0.0 1.5 1 0 0 1 1 1 1 PDZ domain Metallophos PF00149.28 CBK23185.2 - 4.9e-32 112.1 0.0 6.6e-32 111.7 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase OTU PF02338.19 CBK23186.2 - 9.6e-25 87.5 0.2 1.8e-24 86.6 0.0 1.5 2 0 0 2 2 2 1 OTU-like cysteine protease Peptidase_C65 PF10275.9 CBK23186.2 - 5.7e-09 35.8 0.4 6.2e-05 22.6 0.0 2.3 1 1 1 2 2 2 2 Peptidase C65 Otubain Transglut_core3 PF13471.6 CBK23186.2 - 0.02 14.8 0.1 0.031 14.2 0.1 1.4 1 0 0 1 1 1 0 Transglutaminase-like superfamily Calc_CGRP_IAPP PF00214.19 CBK23186.2 - 0.12 12.7 0.7 0.18 12.2 0.7 1.3 1 0 0 1 1 1 0 Calcitonin / CGRP / IAPP family GAS PF13851.6 CBK23186.2 - 0.15 11.4 12.4 0.21 10.9 12.4 1.2 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding DUF2956 PF11169.8 CBK23186.2 - 0.18 12.0 7.1 0.31 11.3 7.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2956) FlaG PF03646.15 CBK23186.2 - 0.35 11.1 8.8 0.63 10.2 8.8 1.3 1 0 0 1 1 1 0 FlaG protein ICA69 PF04629.14 CBK23186.2 - 0.4 11.0 5.1 0.48 10.7 5.1 1.1 1 0 0 1 1 1 0 Islet cell autoantigen ICA69, C-terminal domain MscS_TM PF12794.7 CBK23186.2 - 0.75 8.6 6.5 1.1 8.1 6.5 1.1 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 Mpp10 PF04006.12 CBK23187.2 - 1.3e-87 294.8 59.1 2.3e-68 231.2 12.4 2.0 2 0 0 2 2 2 2 Mpp10 protein Seryl_tRNA_N PF02403.22 CBK23188.2 - 0.0028 17.8 1.2 0.0028 17.8 1.2 4.7 3 1 2 5 5 5 2 Seryl-tRNA synthetase N-terminal domain Lectin_N PF03954.14 CBK23188.2 - 7 6.4 7.1 3.6 7.4 2.4 2.7 1 1 1 2 2 2 0 Hepatic lectin, N-terminal domain DUF4407 PF14362.6 CBK23188.2 - 8.1 5.7 30.4 2.7 7.3 10.6 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) CNOT1_CAF1_bind PF16415.5 CBK23190.2 - 1.1e-47 162.4 2.5 1.4e-47 162.0 2.5 1.1 1 0 0 1 1 1 1 CCR4-NOT transcription complex subunit 1 CAF1-binding domain SNF2_N PF00176.23 CBK23191.2 - 3.9e-59 200.1 1.2 6.2e-59 199.5 1.2 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 CBK23191.2 - 1.3e-21 77.0 0.0 6.2e-20 71.6 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 CBK23191.2 - 3.8e-07 30.3 0.0 9.4e-07 29.0 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 CBK23191.2 - 4.3e-05 22.8 0.1 0.002 17.4 0.0 2.4 2 0 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 Chromo PF00385.24 CBK23191.2 - 0.0004 20.2 0.0 0.001 18.9 0.0 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain DEAD PF00270.29 CBK23191.2 - 0.00061 19.6 0.0 0.0012 18.7 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Glyco_trans_4_3 PF12000.8 CBK23191.2 - 0.12 12.1 0.4 0.25 11.0 0.4 1.5 1 0 0 1 1 1 0 Glycosyl transferase family 4 group DNA_pol_phi PF04931.13 CBK23191.2 - 9.5 4.2 16.9 60 1.5 15.9 2.3 2 0 0 2 2 2 0 DNA polymerase phi TPR_2 PF07719.17 CBK23192.2 - 7.4e-07 28.8 0.8 0.029 14.5 0.1 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.28 CBK23192.2 - 1.5e-05 24.6 0.1 0.0089 15.8 0.0 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.6 CBK23192.2 - 7.8e-05 23.2 0.0 0.00017 22.1 0.0 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_8 PF13181.6 CBK23192.2 - 0.0032 17.6 0.0 1.7 9.1 0.0 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.6 CBK23192.2 - 0.0093 15.9 1.4 0.029 14.4 0.1 2.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.6 CBK23192.2 - 0.054 13.9 0.0 0.45 11.0 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.6 CBK23192.2 - 0.082 13.6 0.2 33 5.4 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 CBK23192.2 - 0.13 13.2 0.2 0.55 11.2 0.0 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat zf-NF-X1 PF01422.17 CBK23193.2 - 6.6e-05 22.9 34.9 0.00035 20.5 14.4 14.0 15 1 0 15 15 15 8 NF-X1 type zinc finger Mac PF12464.8 CBK23193.2 - 0.51 10.6 1.9 2.3 8.5 0.0 2.7 2 0 0 2 2 2 0 Maltose acetyltransferase RRN3 PF05327.11 CBK23193.2 - 2.3 6.7 8.5 4 5.9 8.5 1.3 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Acyl-CoA_dh_1 PF00441.24 CBK23194.2 - 3.2e-33 115.0 0.1 4.9e-33 114.4 0.1 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 CBK23194.2 - 6.5e-29 100.9 0.0 1.7e-28 99.5 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 CBK23194.2 - 1.5e-23 82.8 0.1 2.4e-23 82.1 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 CBK23194.2 - 7.4e-13 48.9 0.0 1.2e-12 48.3 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain NIF PF03031.18 CBK23195.2 - 1.7e-17 63.6 0.1 4.2e-17 62.4 0.1 1.6 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase BRCT PF00533.26 CBK23195.2 - 2.2e-10 40.8 0.0 5.3e-10 39.5 0.0 1.7 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 CBK23195.2 - 1.1e-06 28.5 0.0 2.4e-06 27.4 0.0 1.6 1 0 0 1 1 1 1 twin BRCT domain BRCT_2 PF16589.5 CBK23195.2 - 0.022 15.1 0.0 0.066 13.6 0.0 1.8 1 0 0 1 1 1 0 BRCT domain, a BRCA1 C-terminus domain HAD_2 PF13419.6 CBK23195.2 - 0.023 14.8 2.8 1.2 9.2 0.4 2.8 2 1 0 2 2 2 0 Haloacid dehalogenase-like hydrolase MIEAP PF16026.5 CBK23195.2 - 0.088 13.0 0.1 0.23 11.6 0.1 1.7 1 0 0 1 1 1 0 Mitochondria-eating protein CH PF00307.31 CBK23196.2 - 0.00063 19.9 0.0 0.00097 19.3 0.0 1.2 1 0 0 1 1 1 1 Calponin homology (CH) domain CH_2 PF06294.11 CBK23196.2 - 0.029 14.5 0.0 0.046 13.8 0.0 1.4 1 0 0 1 1 1 0 CH-like domain in sperm protein CAMSAP_CH PF11971.8 CBK23196.2 - 0.2 11.5 0.0 0.33 10.8 0.0 1.3 1 0 0 1 1 1 0 CAMSAP CH domain POR_N PF01855.19 CBK23197.2 - 2.3e-64 217.3 0.2 3.8e-64 216.6 0.2 1.3 1 0 0 1 1 1 1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg POR PF01558.18 CBK23197.2 - 2.8e-28 99.2 0.0 5.6e-28 98.2 0.0 1.6 1 0 0 1 1 1 1 Pyruvate ferredoxin/flavodoxin oxidoreductase PFOR_II PF17147.4 CBK23197.2 - 2.3e-14 53.5 0.3 1.3e-13 51.1 0.1 2.4 2 0 0 2 2 2 1 Pyruvate:ferredoxin oxidoreductase core domain II EKR PF10371.9 CBK23197.2 - 4e-11 42.5 0.0 1.2e-10 41.0 0.0 1.9 1 0 0 1 1 1 1 Domain of unknown function TPP_enzyme_C PF02775.21 CBK23197.2 - 1.3e-08 34.8 1.2 5.8e-08 32.7 0.2 2.6 2 1 1 3 3 3 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Fer4_9 PF13187.6 CBK23197.2 - 3.1e-05 24.1 15.0 0.011 15.9 2.1 3.5 3 0 0 3 3 3 2 4Fe-4S dicluster domain Fer4_7 PF12838.7 CBK23197.2 - 6e-05 23.5 20.0 0.00011 22.8 14.3 3.4 2 1 2 4 4 4 3 4Fe-4S dicluster domain Fer4 PF00037.27 CBK23197.2 - 8.2e-05 22.2 12.3 0.00076 19.2 1.6 4.1 4 0 0 4 4 4 2 4Fe-4S binding domain Fer4_16 PF13484.6 CBK23197.2 - 0.00014 22.7 17.1 0.003 18.5 2.7 3.5 3 0 0 3 3 3 2 4Fe-4S double cluster binding domain Fer4_8 PF13183.6 CBK23197.2 - 0.00067 20.1 12.7 0.025 15.0 10.2 3.0 2 1 0 2 2 2 1 4Fe-4S dicluster domain Fer4_10 PF13237.6 CBK23197.2 - 0.0011 19.0 15.2 0.15 12.2 0.7 3.7 3 0 0 3 3 3 2 4Fe-4S dicluster domain Fer4_21 PF14697.6 CBK23197.2 - 0.01 15.9 13.1 0.01 15.9 13.1 3.2 2 1 0 2 2 2 0 4Fe-4S dicluster domain Transketolase_C PF02780.20 CBK23197.2 - 0.015 15.2 0.0 0.082 12.8 0.0 2.1 2 0 0 2 2 2 0 Transketolase, C-terminal domain Fer4_17 PF13534.6 CBK23197.2 - 0.045 14.3 19.1 0.096 13.2 11.9 3.3 2 1 0 2 2 2 0 4Fe-4S dicluster domain Fer4_6 PF12837.7 CBK23197.2 - 0.048 13.7 30.3 0.03 14.4 4.9 4.5 4 0 0 4 4 4 0 4Fe-4S binding domain Pyr_redox PF00070.27 CBK23197.2 - 0.22 12.1 0.6 18 6.0 0.0 3.2 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Fer4_18 PF13746.6 CBK23197.2 - 1.5 9.0 9.2 2.3 8.4 0.2 3.1 3 0 0 3 3 3 0 4Fe-4S dicluster domain ABC_tran PF00005.27 CBK23198.2 - 7e-14 52.5 0.0 1.2e-13 51.7 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 CBK23198.2 - 3.1e-08 33.8 0.0 3.6e-08 33.6 0.0 1.1 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 CBK23198.2 - 0.097 12.1 0.0 0.13 11.6 0.0 1.2 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain SbcCD_C PF13558.6 CBK23198.2 - 0.16 12.2 0.0 0.93 9.8 0.0 2.1 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit ABC_tran PF00005.27 CBK23199.2 - 1.5e-15 58.0 0.0 2.4e-15 57.3 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 CBK23199.2 - 1.2e-09 38.4 0.0 1.5e-09 38.1 0.0 1.2 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 CBK23199.2 - 0.00078 18.9 0.0 0.0011 18.5 0.0 1.2 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain SbcCD_C PF13558.6 CBK23199.2 - 0.014 15.6 0.1 0.16 12.3 0.1 2.2 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit PGM_PMM_I PF02878.16 CBK23200.2 - 5.8e-28 97.3 0.1 1.1e-27 96.4 0.1 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.16 CBK23200.2 - 1.5e-19 70.2 0.0 3.3e-19 69.1 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.16 CBK23200.2 - 2.9e-09 37.5 0.0 1e-08 35.7 0.0 2.0 1 1 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.20 CBK23200.2 - 2.1e-05 24.6 0.0 6.3e-05 23.1 0.0 1.8 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain LSM PF01423.22 CBK23201.2 - 2.2e-17 62.5 0.0 3.3e-17 61.9 0.0 1.3 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 CBK23201.2 - 0.069 13.3 0.0 0.12 12.5 0.0 1.4 1 0 0 1 1 1 0 Ataxin 2 SM domain Prefoldin PF02996.17 CBK23202.2 - 5.1e-16 58.7 0.1 6e-16 58.4 0.1 1.0 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin_3 PF13758.6 CBK23202.2 - 0.00034 20.6 0.0 0.00061 19.8 0.0 1.4 1 1 0 1 1 1 1 Prefoldin subunit Osmo_CC PF08946.10 CBK23202.2 - 0.00049 20.3 1.5 0.0089 16.3 0.1 2.1 2 0 0 2 2 2 1 Osmosensory transporter coiled coil Prefoldin_2 PF01920.20 CBK23202.2 - 0.001 19.0 0.2 0.02 14.8 0.0 2.0 2 0 0 2 2 2 1 Prefoldin subunit QIL1 PF15884.5 CBK23202.2 - 0.034 14.7 0.1 0.076 13.6 0.0 1.6 2 0 0 2 2 2 0 MICOS complex subunit MIC13, QIL1 Bac_surface_Ag PF01103.23 CBK23203.2 - 6.3e-15 55.5 0.0 8.2e-15 55.1 0.0 1.3 1 1 0 1 1 1 1 Surface antigen zf-MYND PF01753.18 CBK23203.2 - 1.6e-10 40.9 12.6 1.6e-10 40.9 12.6 2.0 2 0 0 2 2 2 1 MYND finger DS PF01916.17 CBK23204.2 - 1.6e-130 434.5 0.0 1.9e-130 434.3 0.0 1.0 1 0 0 1 1 1 1 Deoxyhypusine synthase Carbam_trans_N PF02543.15 CBK23204.2 - 0.044 13.5 0.3 0.066 12.9 0.3 1.2 1 0 0 1 1 1 0 Carbamoyltransferase N-terminus Methyltransf_11 PF08241.12 CBK23205.2 - 2.5e-11 44.1 0.0 1.7e-10 41.4 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 CBK23205.2 - 4e-09 37.1 0.1 1.3e-08 35.4 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 CBK23205.2 - 9e-06 26.4 0.0 1.8e-05 25.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 CBK23205.2 - 1.5e-05 24.9 0.0 2.6e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CBK23205.2 - 3.8e-05 23.5 0.0 8.3e-05 22.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 CBK23205.2 - 0.17 11.2 0.0 0.26 10.6 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family PHD PF00628.29 CBK23206.2 - 5.7e-15 55.0 4.3 1.1e-14 54.1 3.8 1.8 2 0 0 2 2 2 1 PHD-finger zf-PHD-like PF15446.6 CBK23206.2 - 0.026 14.2 3.1 0.028 14.1 0.7 2.1 2 0 0 2 2 2 0 PHD/FYVE-zinc-finger like domain PHD_2 PF13831.6 CBK23206.2 - 0.037 13.6 0.9 0.14 11.7 0.3 2.3 2 0 0 2 2 2 0 PHD-finger DTHCT PF08070.11 CBK23206.2 - 0.06 14.1 2.1 0.17 12.6 2.1 1.7 1 0 0 1 1 1 0 DTHCT (NUC029) region Zf_RING PF16744.5 CBK23206.2 - 0.075 13.2 1.3 0.097 12.8 0.5 1.7 1 1 0 1 1 1 0 KIAA1045 RING finger Prok-RING_1 PF14446.6 CBK23206.2 - 0.13 12.2 1.6 1.3 9.0 0.5 2.3 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 zf-RING_2 PF13639.6 CBK23206.2 - 0.18 12.2 4.4 0.34 11.3 4.4 1.5 1 0 0 1 1 1 0 Ring finger domain Rtf2 PF04641.12 CBK23206.2 - 0.27 10.6 5.1 0.66 9.3 5.1 1.7 1 1 0 1 1 1 0 Rtf2 RING-finger zf-B_box PF00643.24 CBK23206.2 - 0.48 10.6 7.8 0.47 10.6 0.2 2.6 3 0 0 3 3 3 0 B-box zinc finger PHD_4 PF16866.5 CBK23206.2 - 2 8.5 4.9 7.7 6.7 4.9 2.0 1 1 0 1 1 1 0 PHD-finger C1_2 PF03107.16 CBK23206.2 - 2.1 8.7 8.3 0.66 10.3 5.1 1.9 2 0 0 2 2 2 0 C1 domain DZR PF12773.7 CBK23206.2 - 3.1 7.9 6.2 1.3e+02 2.7 6.8 2.3 1 1 1 2 2 2 0 Double zinc ribbon DNA_pol_B_2 PF03175.13 CBK23208.2 - 3.7e-15 55.7 14.2 1.5e-12 47.2 8.1 2.4 2 0 0 2 2 2 2 DNA polymerase type B, organellar and viral Thioredoxin PF00085.20 CBK23210.2 - 5.6e-19 68.0 0.0 1.7e-18 66.5 0.0 1.8 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_6 PF13848.6 CBK23210.2 - 2.2e-15 57.1 0.1 9.6e-12 45.2 0.0 2.9 2 1 1 3 3 3 2 Thioredoxin-like domain Thioredoxin_2 PF13098.6 CBK23210.2 - 2.7e-06 27.8 0.4 3.3e-05 24.3 0.4 2.5 1 1 0 1 1 1 1 Thioredoxin-like domain OST3_OST6 PF04756.13 CBK23210.2 - 0.00094 18.6 0.0 0.0015 18.0 0.0 1.3 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_3 PF13192.6 CBK23210.2 - 0.0095 16.0 0.0 0.026 14.6 0.0 1.7 1 0 0 1 1 1 1 Thioredoxin domain FKBP_C PF00254.28 CBK23212.2 - 5.9e-28 97.0 0.0 1.5e-27 95.7 0.0 1.7 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase NPL PF17800.1 CBK23212.2 - 1.4e-11 44.8 0.2 1.4e-11 44.8 0.2 2.9 2 1 0 2 2 1 1 Nucleoplasmin-like domain Nop14 PF04147.12 CBK23212.2 - 1.3e-05 23.7 32.1 1.5e-05 23.4 32.1 1.0 1 0 0 1 1 1 1 Nop14-like family Presenilin PF01080.17 CBK23212.2 - 0.00056 18.8 13.5 0.00072 18.4 13.5 1.1 1 0 0 1 1 1 1 Presenilin TFIIF_alpha PF05793.12 CBK23212.2 - 0.00081 18.1 36.0 0.001 17.7 36.0 1.1 1 0 0 1 1 1 1 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) YL1 PF05764.13 CBK23212.2 - 0.0019 18.4 34.5 0.0026 17.9 34.5 1.2 1 0 0 1 1 1 1 YL1 nuclear protein CCSAP PF15748.5 CBK23212.2 - 0.0021 18.3 16.0 0.0027 17.9 16.0 1.2 1 0 0 1 1 1 1 Centriole, cilia and spindle-associated CDC45 PF02724.14 CBK23212.2 - 0.0022 16.4 25.8 0.0027 16.1 25.8 1.1 1 0 0 1 1 1 1 CDC45-like protein SDA1 PF05285.12 CBK23212.2 - 0.0062 16.0 39.8 0.008 15.6 39.8 1.1 1 0 0 1 1 1 1 SDA1 HSP70 PF00012.20 CBK23212.2 - 0.0063 14.8 16.9 0.0075 14.5 16.9 1.1 1 0 0 1 1 1 1 Hsp70 protein SLC12 PF03522.15 CBK23212.2 - 0.011 14.8 8.4 0.012 14.7 8.4 1.1 1 0 0 1 1 1 0 Solute carrier family 12 Nop53 PF07767.11 CBK23212.2 - 0.017 14.5 35.5 0.023 14.1 35.5 1.1 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) Mpp10 PF04006.12 CBK23212.2 - 0.022 13.3 38.3 0.028 12.9 38.3 1.1 1 0 0 1 1 1 0 Mpp10 protein GAGA_bind PF06217.12 CBK23212.2 - 0.034 14.4 6.7 0.036 14.3 6.7 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family CCDC106 PF15794.5 CBK23212.2 - 0.045 13.5 13.4 0.064 13.0 13.4 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 DUF4045 PF13254.6 CBK23212.2 - 0.05 13.2 15.1 0.06 13.0 15.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) Mitofilin PF09731.9 CBK23212.2 - 0.056 12.3 23.2 0.072 11.9 23.2 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein SAPS PF04499.15 CBK23212.2 - 0.057 12.2 12.3 0.069 11.9 12.3 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DUF2828 PF11443.8 CBK23212.2 - 0.061 11.4 7.9 0.071 11.2 7.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) DUF913 PF06025.12 CBK23212.2 - 0.069 12.1 9.3 0.094 11.7 9.3 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) RR_TM4-6 PF06459.12 CBK23212.2 - 0.08 12.8 28.5 0.11 12.3 28.5 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Merozoite_SPAM PF07133.11 CBK23212.2 - 0.17 11.9 61.0 0.26 11.3 61.0 1.2 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) RRN3 PF05327.11 CBK23212.2 - 0.25 9.9 18.5 0.34 9.4 18.5 1.3 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 AAA_11 PF13086.6 CBK23212.2 - 0.34 10.6 10.7 0.42 10.3 10.7 1.2 1 0 0 1 1 1 0 AAA domain SID-1_RNA_chan PF13965.6 CBK23212.2 - 0.35 9.2 4.6 0.38 9.1 4.6 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Neur_chan_memb PF02932.16 CBK23212.2 - 0.44 10.6 5.4 0.5 10.4 5.4 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region PA26 PF04636.13 CBK23212.2 - 0.59 9.0 10.0 0.73 8.7 10.0 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) Drc1-Sld2 PF11719.8 CBK23212.2 - 0.59 9.6 23.7 0.79 9.2 23.7 1.1 1 0 0 1 1 1 0 DNA replication and checkpoint protein LTV PF04180.14 CBK23212.2 - 0.6 9.8 22.1 0.77 9.4 22.1 1.1 1 0 0 1 1 1 0 Low temperature viability protein Lin-8 PF03353.15 CBK23212.2 - 0.68 9.4 20.8 0.99 8.9 20.8 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist LAP1C PF05609.12 CBK23212.2 - 0.68 9.0 15.0 0.82 8.7 15.0 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Tub_N PF16322.5 CBK23212.2 - 0.76 10.2 27.6 0.99 9.8 27.6 1.2 1 0 0 1 1 1 0 Tubby N-terminal Apt1 PF10351.9 CBK23212.2 - 0.8 8.5 11.8 1 8.2 11.8 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain BORG_CEP PF14957.6 CBK23212.2 - 1.2 10.3 8.2 2.1 9.6 8.2 1.5 1 0 0 1 1 1 0 Cdc42 effector DUF908 PF06012.12 CBK23212.2 - 1.2 8.5 3.4 1.2 8.5 3.4 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) Raftlin PF15250.6 CBK23212.2 - 1.8 7.3 13.6 2.2 6.9 13.6 1.1 1 0 0 1 1 1 0 Raftlin DUF2151 PF10221.9 CBK23212.2 - 1.8 7.0 15.8 2.4 6.7 15.8 1.1 1 0 0 1 1 1 0 Cell cycle and development regulator BUD22 PF09073.10 CBK23212.2 - 2.3 7.5 34.7 3.2 7.0 34.7 1.1 1 0 0 1 1 1 0 BUD22 TCP PF03634.13 CBK23212.2 - 2.5 8.7 14.8 4 8.0 14.8 1.3 1 0 0 1 1 1 0 TCP family transcription factor DNA_pol_phi PF04931.13 CBK23212.2 - 2.7 6.0 47.0 3.7 5.5 47.0 1.1 1 0 0 1 1 1 0 DNA polymerase phi PI3K_1B_p101 PF10486.9 CBK23212.2 - 2.8 5.6 14.1 4.7 4.9 14.1 1.4 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Hid1 PF12722.7 CBK23212.2 - 3.6 5.6 16.4 4.5 5.3 16.4 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Zip PF02535.22 CBK23212.2 - 3.8 6.6 12.3 5.6 6.1 12.3 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter MDM1 PF15501.6 CBK23212.2 - 5.6 6.0 27.5 7.5 5.6 27.5 1.1 1 0 0 1 1 1 0 Nuclear protein MDM1 TP53IP5 PF15331.6 CBK23212.2 - 5.7 7.0 16.8 9.1 6.4 16.8 1.2 1 0 0 1 1 1 0 Cellular tumour antigen p53-inducible 5 Peptidase_S64 PF08192.11 CBK23212.2 - 8 4.8 11.4 10 4.4 11.4 1.2 1 0 0 1 1 1 0 Peptidase family S64 Glyco_transf_49 PF13896.6 CBK23214.2 - 2.3e-08 33.8 0.3 2.3e-08 33.8 0.3 1.1 1 0 0 1 1 1 1 Glycosyl-transferase for dystroglycan DEAD PF00270.29 CBK23215.2 - 1.9e-38 132.0 0.0 3.5e-38 131.1 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CBK23215.2 - 2.6e-27 95.3 0.6 2.3e-26 92.3 0.0 2.8 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 CBK23215.2 - 8e-24 83.6 0.8 3.1e-23 81.8 0.1 2.3 3 0 0 3 3 3 1 Domain of unknown function (DUF4217) ResIII PF04851.15 CBK23215.2 - 0.0001 22.3 0.0 0.0001 22.3 0.0 2.4 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit SecA_DEAD PF07517.14 CBK23215.2 - 0.35 10.1 0.0 0.35 10.1 0.0 3.0 4 0 0 4 4 4 0 SecA DEAD-like domain DUF3658 PF12395.8 CBK23215.2 - 0.68 9.9 6.2 0.23 11.4 1.9 2.3 2 0 0 2 2 2 0 Protein of unknown function AAA_22 PF13401.6 CBK23215.2 - 1 9.6 5.8 3.3 8.0 0.1 3.2 3 0 0 3 3 3 0 AAA domain Patched PF02460.18 CBK23216.2 - 2.8e-24 85.3 15.5 2.8e-24 85.3 15.5 2.4 2 1 0 2 2 2 1 Patched family LMBR1 PF04791.16 CBK23216.2 - 2.5e-05 23.4 2.7 4.9e-05 22.5 2.7 1.4 1 1 0 1 1 1 1 LMBR1-like membrane protein Sterol-sensing PF12349.8 CBK23216.2 - 0.0014 18.5 9.9 0.0031 17.3 9.9 1.5 1 0 0 1 1 1 1 Sterol-sensing domain of SREBP cleavage-activation LSM PF01423.22 CBK23217.2 - 3.9e-08 32.9 0.1 5.6e-08 32.4 0.1 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 CBK23217.2 - 0.00046 20.3 0.0 0.00065 19.8 0.0 1.3 1 0 0 1 1 1 1 Ataxin 2 SM domain RRM_1 PF00076.22 CBK23218.2 - 2.9e-14 52.6 0.4 0.00029 20.6 0.0 4.6 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF5316 PF17247.2 CBK23218.2 - 0.044 13.8 0.0 0.095 12.7 0.0 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5316) RRM_7 PF16367.5 CBK23218.2 - 0.12 12.5 0.0 1.2 9.3 0.0 2.4 2 0 0 2 2 2 0 RNA recognition motif Exo84_C PF16528.5 CBK23219.2 - 3.7e-24 85.7 0.4 7.1e-24 84.8 0.0 1.6 2 0 0 2 2 2 1 Exocyst component 84 C-terminal Vps51 PF08700.11 CBK23219.2 - 3.7e-13 49.4 0.4 6.7e-13 48.5 0.4 1.4 1 0 0 1 1 1 1 Vps51/Vps67 COG2 PF06148.11 CBK23219.2 - 0.026 14.6 0.1 0.054 13.6 0.1 1.5 1 0 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 Sec8_exocyst PF04048.14 CBK23219.2 - 0.042 13.8 0.1 0.096 12.6 0.1 1.6 1 0 0 1 1 1 0 Sec8 exocyst complex component specific domain WEMBL PF05701.11 CBK23219.2 - 0.38 9.4 1.2 0.54 8.9 0.5 1.4 1 1 0 1 1 1 0 Weak chloroplast movement under blue light Dna2 PF08696.11 CBK23221.2 - 9.3e-29 100.7 0.0 8.9e-28 97.5 0.0 2.1 1 1 0 1 1 1 1 DNA replication factor Dna2 Cas_Cas4 PF01930.17 CBK23221.2 - 0.042 14.0 2.2 1.4 9.1 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function DUF83 AAA_12 PF13087.6 CBK23222.2 - 8.1e-50 169.2 1.8 9.1e-50 169.0 0.7 1.5 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.6 CBK23222.2 - 6e-26 91.8 0.7 9.1e-14 51.9 0.0 2.8 2 1 1 3 3 3 2 AAA domain AAA_30 PF13604.6 CBK23222.2 - 3e-13 49.9 0.0 6.8e-13 48.8 0.0 1.6 1 1 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 CBK23222.2 - 3.5e-09 36.8 0.2 0.0063 16.3 0.0 3.2 3 0 0 3 3 3 3 Viral (Superfamily 1) RNA helicase AAA_19 PF13245.6 CBK23222.2 - 6e-09 36.4 0.0 1.2e-08 35.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain Helicase_RecD PF05127.14 CBK23222.2 - 3.7e-05 23.7 0.0 0.00013 21.9 0.0 2.0 1 1 0 1 1 1 1 Helicase PhoH PF02562.16 CBK23222.2 - 0.01 15.3 0.1 0.05 13.0 0.0 2.3 2 1 0 2 2 2 0 PhoH-like protein ResIII PF04851.15 CBK23222.2 - 0.011 15.8 0.1 0.039 14.0 0.0 2.0 2 1 0 2 2 1 0 Type III restriction enzyme, res subunit UvrD_C_2 PF13538.6 CBK23222.2 - 0.021 14.7 0.0 0.047 13.5 0.0 1.7 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain AAA_33 PF13671.6 CBK23222.2 - 0.032 14.4 0.0 0.84 9.8 0.0 2.4 2 1 0 2 2 2 0 AAA domain PIN_10 PF18478.1 CBK23222.2 - 0.071 13.3 0.0 7.2 6.9 0.0 2.4 2 0 0 2 2 2 0 PIN like domain cobW PF02492.19 CBK23222.2 - 0.13 11.8 0.1 0.55 9.8 0.1 2.1 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain DUF2075 PF09848.9 CBK23222.2 - 0.14 11.4 0.3 1 8.5 0.3 2.4 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_18 PF13238.6 CBK23222.2 - 0.17 12.5 0.2 0.9 10.1 0.0 2.2 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.6 CBK23222.2 - 0.21 11.2 0.0 0.43 10.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain DUF3524 PF12038.8 CBK23223.2 - 1.4e-60 204.0 0.0 2.2e-60 203.3 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3524) Glycos_transf_1 PF00534.20 CBK23223.2 - 7.7e-10 38.6 0.0 1.5e-09 37.6 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 CBK23223.2 - 0.00011 22.7 0.0 0.0015 19.0 0.0 2.1 2 0 0 2 2 2 1 Glycosyl transferases group 1 DUF3801 PF12687.7 CBK23224.2 - 0.0076 16.3 4.6 0.0084 16.2 4.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3801) DUF1635 PF07795.11 CBK23224.2 - 0.021 14.7 6.1 0.03 14.2 6.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1635) HAP1_N PF04849.13 CBK23224.2 - 0.059 12.6 11.5 0.11 11.7 11.0 1.7 2 0 0 2 2 2 0 HAP1 N-terminal conserved region SlyX PF04102.12 CBK23224.2 - 0.063 13.9 7.3 5.7 7.6 3.9 2.5 1 1 1 2 2 2 0 SlyX LUC7 PF03194.15 CBK23224.2 - 0.078 12.6 8.7 0.098 12.3 8.7 1.3 1 0 0 1 1 1 0 LUC7 N_terminus ADIP PF11559.8 CBK23224.2 - 0.1 12.7 12.2 0.16 12.0 12.2 1.2 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding Lectin_N PF03954.14 CBK23224.2 - 0.13 12.0 4.9 0.25 11.1 4.9 1.5 1 0 0 1 1 1 0 Hepatic lectin, N-terminal domain CENP-H PF05837.12 CBK23224.2 - 0.13 12.6 14.0 0.24 11.8 14.0 1.3 1 0 0 1 1 1 0 Centromere protein H (CENP-H) RPW8 PF05659.11 CBK23224.2 - 0.15 11.7 8.0 0.65 9.7 8.2 1.8 2 0 0 2 2 2 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 Herpes_UL6 PF01763.16 CBK23224.2 - 0.18 10.3 5.4 0.23 9.9 5.4 1.1 1 0 0 1 1 1 0 Herpesvirus UL6 like Calc_CGRP_IAPP PF00214.19 CBK23224.2 - 0.21 12.0 6.5 1.8 8.9 6.5 2.1 1 1 0 1 1 1 0 Calcitonin / CGRP / IAPP family Sas10_Utp3 PF04000.15 CBK23224.2 - 0.26 11.9 4.0 0.52 11.0 4.0 1.5 1 0 0 1 1 1 0 Sas10/Utp3/C1D family GLE1 PF07817.13 CBK23224.2 - 0.41 9.8 4.5 0.54 9.4 4.5 1.1 1 0 0 1 1 1 0 GLE1-like protein Swi5 PF07061.11 CBK23224.2 - 0.79 9.8 14.2 0.23 11.6 9.4 2.2 1 1 1 2 2 2 0 Swi5 ZapB PF06005.12 CBK23224.2 - 0.94 10.0 17.4 6 7.4 11.0 2.5 1 1 1 2 2 2 0 Cell division protein ZapB Exonuc_VII_L PF02601.15 CBK23224.2 - 1.5 8.3 6.6 1.8 8.1 6.6 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit DivIC PF04977.15 CBK23224.2 - 1.6 8.5 10.7 6.7 6.6 4.8 2.4 1 1 1 2 2 2 0 Septum formation initiator YlqD PF11068.8 CBK23224.2 - 2.3 8.6 13.2 3.3 8.1 13.2 1.3 1 0 0 1 1 1 0 YlqD protein Presenilin PF01080.17 CBK23224.2 - 2.7 6.7 4.2 3.1 6.5 4.2 1.1 1 0 0 1 1 1 0 Presenilin DUF1664 PF07889.12 CBK23224.2 - 2.7 8.0 6.5 4.5 7.3 6.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) FYVE_2 PF02318.16 CBK23224.2 - 3 8.1 8.5 15 5.8 5.4 2.3 2 0 0 2 2 2 0 FYVE-type zinc finger Fmp27_WPPW PF10359.9 CBK23224.2 - 4.5 6.0 12.7 4.6 6.0 12.7 1.3 1 1 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain DUF4407 PF14362.6 CBK23224.2 - 4.8 6.4 10.5 5.5 6.2 10.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Mu-like_Pro PF10123.9 CBK23224.2 - 5.8 6.4 11.8 7.3 6.1 11.8 1.1 1 0 0 1 1 1 0 Mu-like prophage I protein DUF2951 PF11166.8 CBK23224.2 - 5.9 7.2 8.6 10 6.4 8.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2951) Med9 PF07544.13 CBK23224.2 - 6.6 6.9 12.2 1.7 8.7 4.6 2.3 1 1 1 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 XhlA PF10779.9 CBK23224.2 - 8.4 6.7 12.8 1.4 9.1 8.9 1.8 2 0 0 2 2 1 0 Haemolysin XhlA PTP2 PF17022.5 CBK23224.2 - 9.5 5.8 14.6 35 3.9 10.8 2.1 2 0 0 2 2 2 0 Polar tube protein 2 from Microsporidia CAF1C_H4-bd PF12265.8 CBK23227.2 - 2.2e-13 50.2 2.2 5.3e-13 49.0 2.2 1.7 1 1 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex WD40 PF00400.32 CBK23227.2 - 0.19 12.6 0.8 0.19 12.6 0.8 2.1 2 1 0 2 2 2 0 WD domain, G-beta repeat Myb_DNA-binding PF00249.31 CBK23228.2 - 2.7e-07 30.7 0.0 6.9e-07 29.4 0.0 1.6 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 CBK23228.2 - 2.3e-06 27.4 0.8 2.3e-06 27.4 0.8 1.9 2 0 0 2 2 2 1 Myb DNA-binding like Gly_acyl_tr_N PF06021.11 CBK23228.2 - 0.0037 17.4 0.1 0.0047 17.0 0.1 1.1 1 0 0 1 1 1 1 Aralkyl acyl-CoA:amino acid N-acyltransferase Toxin_R_bind_C PF07951.12 CBK23228.2 - 0.064 12.9 0.1 0.079 12.6 0.1 1.1 1 0 0 1 1 1 0 Clostridium neurotoxin, C-terminal receptor binding Myb_DNA-bind_6 PF13921.6 CBK23228.2 - 0.16 12.2 2.1 0.24 11.7 0.3 2.0 2 0 0 2 2 2 0 Myb-like DNA-binding domain T2SSK PF03934.13 CBK23229.2 - 0.086 12.2 0.0 0.097 12.0 0.0 1.1 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein K Methyltransf_32 PF13679.6 CBK23230.2 - 2.5e-11 43.8 2.2 3.3e-11 43.4 2.2 1.2 1 0 0 1 1 1 1 Methyltransferase domain potato_inhibit PF00280.18 CBK23231.2 - 1.2e-16 61.1 0.7 1.3e-16 60.9 0.7 1.0 1 0 0 1 1 1 1 Potato inhibitor I family Inhibitor_I78 PF11720.8 CBK23231.2 - 0.00019 21.4 0.0 0.00022 21.2 0.0 1.2 1 0 0 1 1 1 1 Peptidase inhibitor I78 family tRNA-synt_1d PF00750.19 CBK23232.2 - 6.4e-122 406.8 0.0 8.8e-122 406.4 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (R) DALR_1 PF05746.15 CBK23232.2 - 5.1e-31 107.3 0.0 1.3e-30 106.0 0.0 1.7 1 0 0 1 1 1 1 DALR anticodon binding domain Arg_tRNA_synt_N PF03485.16 CBK23232.2 - 2.2e-16 60.2 0.0 4.9e-15 55.9 0.0 2.6 2 0 0 2 2 2 1 Arginyl tRNA synthetase N terminal domain tRNA-synt_1e PF01406.19 CBK23232.2 - 9.4e-05 21.9 0.0 0.00018 21.0 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.11 CBK23232.2 - 0.001 17.9 0.0 0.0014 17.4 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (M) SBP_bac_5 PF00496.22 CBK23232.2 - 0.21 10.5 0.0 0.32 9.9 0.0 1.2 1 0 0 1 1 1 0 Bacterial extracellular solute-binding proteins, family 5 Middle OTCace_N PF02729.21 CBK23233.2 - 1e-36 126.2 0.0 1.5e-36 125.6 0.0 1.3 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain OTCace PF00185.24 CBK23233.2 - 2.2e-11 44.1 0.0 4.4e-11 43.1 0.0 1.5 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain DnaJ_C PF01556.18 CBK23234.2 - 1e-31 110.0 0.0 1.4e-31 109.6 0.0 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 CBK23234.2 - 7.2e-22 77.3 0.6 1.3e-21 76.5 0.6 1.4 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 CBK23234.2 - 2.8e-11 43.6 7.3 5.3e-11 42.7 7.3 1.5 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 CBK23234.2 - 0.0069 16.3 9.5 0.029 14.3 0.5 2.7 1 1 2 3 3 3 3 Tryptophan RNA-binding attenuator protein inhibitory protein HypA PF01155.19 CBK23234.2 - 0.02 14.9 5.3 4.5 7.3 5.2 2.5 1 1 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Cytochrome_C7 PF14522.6 CBK23234.2 - 0.026 14.5 2.9 0.071 13.1 2.6 1.9 1 1 0 1 1 1 0 Cytochrome c7 and related cytochrome c Cytochrome_CBB3 PF13442.6 CBK23234.2 - 5.3 7.4 6.2 14 6.0 0.4 2.9 2 1 0 2 2 2 0 Cytochrome C oxidase, cbb3-type, subunit III HA2 PF04408.23 CBK23235.2 - 3.1e-17 62.8 0.0 6.7e-17 61.7 0.0 1.5 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 CBK23235.2 - 4.2e-17 62.3 0.0 1.3e-16 60.7 0.0 2.0 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 CBK23235.2 - 2.1e-14 53.8 0.0 5.7e-14 52.4 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 CBK23235.2 - 3.6e-07 30.1 0.0 1.6e-06 28.0 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.6 CBK23235.2 - 0.00048 20.4 0.0 0.0019 18.5 0.0 2.0 1 1 0 1 1 1 1 AAA domain ATPase PF06745.13 CBK23235.2 - 0.018 14.4 0.0 0.045 13.1 0.0 1.6 1 0 0 1 1 1 0 KaiC T2SSE PF00437.20 CBK23235.2 - 0.037 13.1 0.0 0.069 12.2 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_14 PF13173.6 CBK23235.2 - 0.16 12.0 0.0 24 4.9 0.0 2.8 3 0 0 3 3 3 0 AAA domain zf-C2H2_6 PF13912.6 CBK23236.2 - 0.047 13.7 1.7 0.095 12.7 1.7 1.5 1 0 0 1 1 1 0 C2H2-type zinc finger Sulfolobus_pRN PF05584.11 CBK23236.2 - 0.065 13.3 0.4 0.18 11.8 0.1 1.9 2 0 0 2 2 2 0 Sulfolobus plasmid regulatory protein HIT PF01230.23 CBK23237.2 - 1.8e-25 89.5 0.0 2.6e-25 89.0 0.0 1.3 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 CBK23237.2 - 4.8e-20 72.2 0.1 6.6e-20 71.7 0.1 1.2 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding His_biosynth PF00977.21 CBK23237.2 - 0.097 12.1 0.0 0.18 11.3 0.0 1.3 1 0 0 1 1 1 0 Histidine biosynthesis protein KTI12 PF08433.10 CBK23238.2 - 1.9e-59 201.4 1.9 4.6e-59 200.1 1.9 1.5 1 1 0 1 1 1 1 Chromatin associated protein KTI12 AAA_33 PF13671.6 CBK23238.2 - 5.5e-07 29.8 0.0 1.6e-06 28.4 0.0 1.8 1 1 0 1 1 1 1 AAA domain ATP_bind_1 PF03029.17 CBK23238.2 - 0.00059 19.7 0.0 0.002 17.9 0.0 1.9 1 1 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_14 PF13173.6 CBK23238.2 - 0.0015 18.5 0.0 0.0035 17.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain APS_kinase PF01583.20 CBK23238.2 - 0.0074 16.2 0.0 0.012 15.5 0.0 1.3 1 0 0 1 1 1 1 Adenylylsulphate kinase BK_channel_a PF03493.18 CBK23238.2 - 0.041 14.1 2.5 3.3 7.9 0.1 2.8 3 0 0 3 3 3 0 Calcium-activated BK potassium channel alpha subunit ER_lumen_recept PF00810.18 CBK23239.2 - 2.8e-35 122.3 4.8 2.8e-35 122.3 4.8 1.9 2 0 0 2 2 2 1 ER lumen protein retaining receptor Metallophos PF00149.28 CBK23240.2 - 4.9e-11 43.5 0.1 6.5e-11 43.1 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Mid2 PF04478.12 CBK23240.2 - 0.023 14.6 0.0 0.044 13.6 0.0 1.4 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor MORN PF02493.20 CBK23241.2 - 0.0058 16.5 2.4 0.0058 16.5 2.4 5.7 8 0 0 8 8 8 1 MORN repeat MORN_2 PF07661.13 CBK23241.2 - 1.6 9.2 8.5 24 5.6 0.1 5.0 5 1 1 6 6 6 0 MORN repeat variant Syntaxin PF00804.25 CBK23242.2 - 9.2e-06 25.5 1.9 9.9e-06 25.4 1.9 1.1 1 0 0 1 1 1 1 Syntaxin Ras PF00071.22 CBK23243.2 - 6.5e-41 139.6 0.0 7.7e-41 139.4 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CBK23243.2 - 4.6e-26 91.4 0.0 7.4e-26 90.7 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CBK23243.2 - 3.6e-15 55.8 0.0 4.6e-15 55.5 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 CBK23243.2 - 1.2e-07 31.5 0.0 2.3e-05 24.0 0.0 2.5 1 1 1 2 2 2 2 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 CBK23243.2 - 1e-05 25.1 0.0 1.2e-05 24.8 0.0 1.3 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 CBK23243.2 - 1.1e-05 25.5 0.0 5.1e-05 23.2 0.0 1.8 1 1 0 2 2 2 1 RsgA GTPase MMR_HSR1 PF01926.23 CBK23243.2 - 0.00018 21.6 0.0 0.00029 20.9 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 CBK23243.2 - 0.009 15.6 0.0 0.39 10.2 0.0 2.4 1 1 0 1 1 1 1 Ferrous iron transport protein B SRPRB PF09439.10 CBK23243.2 - 0.012 15.1 0.0 0.014 14.8 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Beta_elim_lyase PF01212.21 CBK23244.2 - 6.4e-75 252.1 0.0 8.2e-75 251.8 0.0 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase SepSecS PF05889.13 CBK23244.2 - 9.1e-05 21.3 0.0 0.00015 20.6 0.0 1.2 1 0 0 1 1 1 1 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS Aminotran_1_2 PF00155.21 CBK23244.2 - 0.0062 15.8 0.0 0.028 13.6 0.0 2.0 2 0 0 2 2 2 1 Aminotransferase class I and II Pyridoxal_deC PF00282.19 CBK23244.2 - 0.011 14.4 0.0 0.019 13.7 0.0 1.3 1 0 0 1 1 1 0 Pyridoxal-dependent decarboxylase conserved domain ABC1 PF03109.16 CBK23245.2 - 6.8e-32 110.1 0.2 3.8e-31 107.7 0.0 2.1 2 0 0 2 2 2 1 ABC1 family DIMCO_N PF16844.5 CBK23245.2 - 0.13 12.6 0.2 0.35 11.2 0.2 1.7 1 0 0 1 1 1 0 Dinitrogenase iron-molybdenum cofactor, N-terminal Mitoc_mL59 PF18126.1 CBK23245.2 - 4.9 7.5 5.9 8.6 6.7 5.9 1.3 1 0 0 1 1 1 0 Mitochondrial ribosomal protein mL59 AAA PF00004.29 CBK23246.2 - 4e-38 130.8 0.0 9.4e-38 129.6 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CBK23246.2 - 1.8e-09 37.2 0.0 7.2e-09 35.3 0.0 2.1 2 0 0 2 2 1 1 AAA+ lid domain AAA_5 PF07728.14 CBK23246.2 - 4.6e-06 26.7 0.0 1.7e-05 24.9 0.0 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 CBK23246.2 - 5.3e-06 26.8 0.9 0.0009 19.5 0.2 3.1 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 CBK23246.2 - 1.6e-05 25.3 0.3 0.0026 18.2 0.1 3.3 2 1 0 2 2 2 1 AAA ATPase domain AAA_14 PF13173.6 CBK23246.2 - 2.4e-05 24.4 0.0 0.00039 20.5 0.0 2.5 1 1 1 2 2 2 1 AAA domain RuvB_N PF05496.12 CBK23246.2 - 3.7e-05 23.5 0.0 8.6e-05 22.3 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain IstB_IS21 PF01695.17 CBK23246.2 - 3.8e-05 23.5 0.0 8.1e-05 22.4 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein TIP49 PF06068.13 CBK23246.2 - 5.8e-05 22.5 0.0 0.00024 20.5 0.0 2.0 2 1 1 3 3 3 1 TIP49 P-loop domain AAA_33 PF13671.6 CBK23246.2 - 0.00012 22.3 0.0 0.0003 20.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_2 PF07724.14 CBK23246.2 - 0.0004 20.6 0.1 0.0016 18.6 0.0 2.0 3 0 0 3 3 1 1 AAA domain (Cdc48 subfamily) AAA_18 PF13238.6 CBK23246.2 - 0.0007 20.1 0.0 0.0026 18.3 0.0 2.1 1 1 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 CBK23246.2 - 0.0019 17.6 0.2 0.0052 16.2 0.2 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI TsaE PF02367.17 CBK23246.2 - 0.0036 17.3 0.0 0.0097 15.9 0.0 1.7 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_24 PF13479.6 CBK23246.2 - 0.0081 15.9 0.0 0.018 14.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_7 PF12775.7 CBK23246.2 - 0.0096 15.5 0.0 0.02 14.4 0.0 1.5 1 1 0 1 1 1 1 P-loop containing dynein motor region RNA_helicase PF00910.22 CBK23246.2 - 0.013 15.9 0.0 0.058 13.8 0.0 2.2 2 0 0 2 2 1 0 RNA helicase AAA_28 PF13521.6 CBK23246.2 - 0.017 15.3 0.0 0.042 14.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain Hydin_ADK PF17213.3 CBK23246.2 - 0.019 15.2 0.2 1.3 9.3 0.0 2.7 2 0 0 2 2 2 0 Hydin Adenylate kinase-like domain Sigma54_activ_2 PF14532.6 CBK23246.2 - 0.02 15.0 0.0 0.045 13.9 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_25 PF13481.6 CBK23246.2 - 0.032 13.8 0.3 0.51 9.9 0.2 2.7 2 1 0 3 3 3 0 AAA domain Trypan_PARP PF05887.11 CBK23246.2 - 0.045 13.7 0.2 0.21 11.6 0.2 2.1 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) TniB PF05621.11 CBK23246.2 - 0.049 13.0 0.0 3.7 6.9 0.0 2.4 1 1 1 2 2 2 0 Bacterial TniB protein Rad17 PF03215.15 CBK23246.2 - 0.07 13.0 2.0 0.17 11.8 0.0 2.5 3 0 0 3 3 3 0 Rad17 P-loop domain AAA_17 PF13207.6 CBK23246.2 - 0.08 13.4 0.0 0.56 10.6 0.0 2.5 2 0 0 2 2 1 0 AAA domain NACHT PF05729.12 CBK23246.2 - 0.12 12.2 0.1 0.57 10.1 0.0 2.0 1 1 1 2 2 2 0 NACHT domain Oxidored_FMN PF00724.20 CBK23248.2 - 7.6e-65 219.4 0.0 8.9e-65 219.2 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family PCI PF01399.27 CBK23249.2 - 1.3e-08 35.2 0.8 1.6e-08 35.0 0.8 1.1 1 0 0 1 1 1 1 PCI domain Rrp15p PF07890.12 CBK23250.2 - 5.8e-11 42.9 12.7 5.8e-11 42.9 12.7 2.3 2 1 1 3 3 3 1 Rrp15p FRG PF08867.11 CBK23250.2 - 0.21 12.5 0.2 0.21 12.5 0.2 2.3 2 1 0 2 2 2 0 FRG domain Prominin PF05478.11 CBK23250.2 - 8.8 4.1 7.1 13 3.6 7.1 1.3 1 1 0 1 1 1 0 Prominin Hist_deacetyl PF00850.19 CBK23251.2 - 3.8e-81 272.9 0.0 5.7e-81 272.3 0.0 1.2 1 0 0 1 1 1 1 Histone deacetylase domain Pkinase PF00069.25 CBK23252.2 - 9.7e-51 172.6 0.0 3.7e-50 170.8 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBK23252.2 - 3.6e-21 75.6 0.1 8.1e-21 74.5 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase Haspin_kinase PF12330.8 CBK23252.2 - 0.00021 20.4 0.1 0.00045 19.3 0.1 1.5 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 CBK23252.2 - 0.0032 16.9 0.9 0.012 14.9 0.0 2.0 2 0 0 2 2 2 1 Kinase-like MFS_1 PF07690.16 CBK23253.2 - 9.5e-28 97.1 13.9 9.5e-28 97.1 13.9 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 CBK23253.2 - 1.3e-19 70.5 17.4 2.1e-19 69.8 17.3 1.3 1 1 0 1 1 1 1 Sugar (and other) transporter PigN PF04987.14 CBK23253.2 - 0.13 11.1 24.3 0.024 13.5 17.7 2.2 1 1 1 2 2 2 0 Phosphatidylinositolglycan class N (PIG-N) Lig_chan PF00060.26 CBK23253.2 - 1.9 8.3 4.4 33 4.3 0.0 2.6 2 0 0 2 2 2 0 Ligand-gated ion channel MFS_1 PF07690.16 CBK23254.2 - 1.9e-08 33.6 20.5 8e-07 28.3 17.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Glu_cyclase_2 PF05096.12 CBK23255.2 - 4.6e-31 108.2 1.1 5.3e-31 108.0 1.1 1.0 1 0 0 1 1 1 1 Glutamine cyclotransferase SBBP PF06739.11 CBK23255.2 - 0.11 12.5 0.0 0.27 11.2 0.0 1.6 1 0 0 1 1 1 0 Beta-propeller repeat MFS_1 PF07690.16 CBK23256.2 - 8.9e-15 54.5 43.0 1.5e-12 47.1 14.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Glu_cyclase_2 PF05096.12 CBK23257.2 - 1.6e-51 175.2 1.9 3.9e-51 173.9 1.8 1.5 1 1 0 1 1 1 1 Glutamine cyclotransferase DUF4346 PF14251.6 CBK23257.2 - 0.066 13.3 0.0 0.88 9.6 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4346) PFK PF00365.20 CBK23261.2 - 8.6e-27 94.2 0.0 6.4e-26 91.3 0.0 2.1 1 1 0 1 1 1 1 Phosphofructokinase RsgA_N PF16745.5 CBK23261.2 - 0.055 13.2 0.1 6.9 6.5 0.0 2.5 2 0 0 2 2 2 0 RsgA N-terminal domain Amelogenin PF02948.15 CBK23262.2 - 0.078 13.6 4.7 0.17 12.5 1.3 2.1 1 1 1 2 2 2 0 Amelogenin DUF5427 PF10310.9 CBK23262.2 - 3.5 6.5 11.1 4 6.3 11.1 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5427) DUF4375 PF14300.6 CBK23262.2 - 5.2 7.4 8.4 1.7 9.0 0.8 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4375) DUF5600 PF18150.1 CBK23263.2 - 1.5e-37 128.5 0.8 4.8e-37 126.8 0.4 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF5600) EF-hand_4 PF12763.7 CBK23263.2 - 1.3e-18 66.9 0.7 4.7e-18 65.1 0.0 2.2 3 0 0 3 3 3 1 Cytoskeletal-regulatory complex EF hand Dynamin_N PF00350.23 CBK23263.2 - 1.1e-13 51.6 0.0 3.1e-12 46.9 0.0 2.4 1 1 0 1 1 1 1 Dynamin family EHD_N PF16880.5 CBK23263.2 - 1.8e-11 43.7 0.4 3.4e-11 42.8 0.4 1.5 1 0 0 1 1 1 1 N-terminal EH-domain containing protein MMR_HSR1 PF01926.23 CBK23263.2 - 3e-09 37.0 0.0 7.9e-09 35.6 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase EF-hand_1 PF00036.32 CBK23263.2 - 0.00017 20.9 0.3 0.00091 18.6 0.1 2.4 2 0 0 2 2 2 1 EF hand Roc PF08477.13 CBK23263.2 - 0.002 18.3 0.1 0.74 10.0 0.0 2.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Gtr1_RagA PF04670.12 CBK23263.2 - 0.0092 15.4 0.0 0.17 11.2 0.0 2.4 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 CBK23263.2 - 0.02 14.4 0.0 0.057 13.0 0.0 1.8 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain EF-hand_6 PF13405.6 CBK23263.2 - 0.039 13.9 0.0 1.1 9.4 0.1 2.9 2 0 0 2 2 2 0 EF-hand domain RsgA_GTPase PF03193.16 CBK23263.2 - 0.081 12.8 0.0 11 5.9 0.0 2.7 3 0 0 3 3 3 0 RsgA GTPase AAA_16 PF13191.6 CBK23263.2 - 0.086 13.2 0.0 0.41 11.0 0.0 2.1 2 1 0 2 2 2 0 AAA ATPase domain AIG1 PF04548.16 CBK23263.2 - 0.14 11.5 0.0 0.39 10.0 0.0 1.7 1 0 0 1 1 1 0 AIG1 family WD40 PF00400.32 CBK23264.2 - 4e-21 74.9 8.2 0.0012 19.6 0.1 7.1 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBK23264.2 - 1.3e-06 28.6 0.1 0.3 11.4 0.1 3.6 1 1 1 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 CBK23264.2 - 3.1e-06 26.8 0.1 2.7e-05 23.7 0.1 1.7 1 1 1 2 2 2 2 WD40-like domain BBS2_Mid PF14783.6 CBK23264.2 - 0.0021 18.1 0.1 2.6 8.1 0.0 3.4 2 1 0 3 3 3 1 Ciliary BBSome complex subunit 2, middle region Rav1p_C PF12234.8 CBK23265.2 - 3.7e-39 134.7 2.1 2.5e-36 125.4 0.2 2.2 2 0 0 2 2 2 2 RAVE protein 1 C terminal WT1 PF02165.15 CBK23266.2 - 0.0026 17.1 0.0 0.003 16.8 0.0 1.0 1 0 0 1 1 1 1 Wilm's tumour protein AAA PF00004.29 CBK23267.2 - 6.5e-45 152.8 0.0 1.7e-44 151.5 0.0 1.7 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.14 CBK23267.2 - 3.9e-08 33.6 0.0 1.3e-07 31.9 0.0 1.8 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_lid_3 PF17862.1 CBK23267.2 - 9.7e-08 31.7 0.0 2.1e-07 30.6 0.0 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 CBK23267.2 - 1.2e-07 31.8 0.1 3.3e-07 30.4 0.1 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 CBK23267.2 - 2.3e-05 24.8 0.0 0.0009 19.7 0.0 2.2 1 1 1 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 CBK23267.2 - 3.1e-05 24.3 0.4 0.02 15.1 0.0 2.5 1 1 1 2 2 2 1 AAA domain DUF815 PF05673.13 CBK23267.2 - 5.2e-05 22.5 0.0 0.0001 21.5 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) RuvB_N PF05496.12 CBK23267.2 - 6.9e-05 22.6 0.0 0.00019 21.2 0.0 1.6 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 CBK23267.2 - 0.00015 22.3 0.0 0.00091 19.8 0.0 2.1 1 1 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 CBK23267.2 - 0.00027 20.4 0.2 0.00075 18.9 0.1 1.8 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI Prot_ATP_ID_OB PF16450.5 CBK23267.2 - 0.00028 20.8 0.0 0.00062 19.7 0.0 1.6 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_33 PF13671.6 CBK23267.2 - 0.00089 19.4 0.0 0.003 17.7 0.0 1.9 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 CBK23267.2 - 0.0015 18.3 0.0 0.0056 16.4 0.0 1.8 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_7 PF12775.7 CBK23267.2 - 0.0023 17.5 0.1 0.008 15.7 0.1 1.8 1 1 0 1 1 1 1 P-loop containing dynein motor region TIP49 PF06068.13 CBK23267.2 - 0.0027 17.0 0.0 0.0062 15.8 0.0 1.5 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_28 PF13521.6 CBK23267.2 - 0.0043 17.3 0.0 0.007 16.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.6 CBK23267.2 - 0.0043 17.1 0.0 0.009 16.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain Sigma54_activat PF00158.26 CBK23267.2 - 0.0049 16.6 0.1 0.1 12.3 0.0 2.4 2 1 0 2 2 2 1 Sigma-54 interaction domain Parvo_NS1 PF01057.17 CBK23267.2 - 0.01 14.9 0.0 0.018 14.1 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 RNA_helicase PF00910.22 CBK23267.2 - 0.014 15.8 0.0 0.036 14.5 0.0 1.8 1 0 0 1 1 1 0 RNA helicase AAA_24 PF13479.6 CBK23267.2 - 0.014 15.1 0.1 0.033 13.9 0.1 1.6 1 1 0 1 1 1 0 AAA domain AAA_30 PF13604.6 CBK23267.2 - 0.015 15.0 0.0 0.028 14.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 CBK23267.2 - 0.018 15.0 0.1 0.081 12.8 0.0 2.2 3 0 0 3 3 2 0 NACHT domain ATPase PF06745.13 CBK23267.2 - 0.023 14.0 0.1 0.37 10.1 0.0 2.1 2 0 0 2 2 2 0 KaiC Zeta_toxin PF06414.12 CBK23267.2 - 0.038 13.3 0.0 0.077 12.3 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_3 PF07726.11 CBK23267.2 - 0.046 13.6 0.0 0.12 12.3 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 CBK23267.2 - 0.079 12.4 0.7 0.15 11.5 0.1 1.7 2 0 0 2 2 2 0 PhoH-like protein TsaE PF02367.17 CBK23267.2 - 0.11 12.5 0.0 0.2 11.7 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ATPase_2 PF01637.18 CBK23267.2 - 0.12 12.2 0.0 0.97 9.3 0.0 2.2 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea AAA_11 PF13086.6 CBK23267.2 - 0.15 11.8 0.0 0.25 11.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain Bac_DnaA PF00308.18 CBK23267.2 - 0.16 11.8 0.0 0.3 10.9 0.0 1.5 1 1 0 1 1 1 0 Bacterial dnaA protein AAA_25 PF13481.6 CBK23267.2 - 0.17 11.4 0.3 0.38 10.3 0.2 1.5 1 1 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 CBK23267.2 - 0.19 11.6 1.3 5.8 6.8 0.0 3.0 3 1 1 4 4 3 0 NTPase DUF89 PF01937.19 CBK23268.2 - 2.2e-56 191.4 0.0 2.4e-56 191.2 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF89 Ribosomal_L1 PF00687.21 CBK23269.2 - 2.3e-32 112.4 1.2 2.3e-32 112.4 1.2 2.6 2 1 1 3 3 3 1 Ribosomal protein L1p/L10e family CDC45 PF02724.14 CBK23269.2 - 0.73 8.0 21.8 1.1 7.4 21.8 1.2 1 0 0 1 1 1 0 CDC45-like protein YL1 PF05764.13 CBK23269.2 - 0.99 9.5 37.3 1.8 8.6 37.3 1.3 1 0 0 1 1 1 0 YL1 nuclear protein GREB1 PF15782.5 CBK23269.2 - 1.2 6.1 12.7 1.7 5.7 12.7 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer SIR4_SID PF16991.5 CBK23269.2 - 1.8 8.6 19.6 3.4 7.7 19.6 1.5 1 0 0 1 1 1 0 Sir4 SID domain TP53IP5 PF15331.6 CBK23269.2 - 6.4 6.9 22.8 15 5.6 22.8 1.6 1 0 0 1 1 1 0 Cellular tumour antigen p53-inducible 5 zf-C3HC4_3 PF13920.6 CBK23270.2 - 8.4e-12 44.8 7.6 1.3e-11 44.2 7.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CBK23270.2 - 6.9e-10 38.6 9.5 1.2e-09 37.9 9.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 CBK23270.2 - 3.5e-09 36.3 12.4 5.5e-09 35.7 12.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CBK23270.2 - 6.9e-09 35.9 12.9 1.1e-08 35.2 12.9 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 CBK23270.2 - 9.9e-09 35.1 10.9 4e-08 33.2 7.2 2.3 2 0 0 2 2 2 1 RING-type zinc-finger Prok-RING_4 PF14447.6 CBK23270.2 - 2e-08 34.0 10.5 4.1e-08 33.0 10.5 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 CBK23270.2 - 2.9e-06 27.1 8.9 7.7e-06 25.8 8.5 1.9 1 1 1 2 2 2 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 CBK23270.2 - 4e-06 26.9 10.8 8.1e-06 25.9 10.8 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.7 CBK23270.2 - 0.00091 19.5 8.5 0.0018 18.6 8.5 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_10 PF16685.5 CBK23270.2 - 0.0095 16.1 5.9 0.018 15.2 5.9 1.4 1 0 0 1 1 1 1 zinc RING finger of MSL2 Rtf2 PF04641.12 CBK23270.2 - 0.013 14.9 0.6 0.016 14.6 0.6 1.2 1 0 0 1 1 1 0 Rtf2 RING-finger zf-NOSIP PF15906.5 CBK23270.2 - 0.017 15.3 0.3 0.028 14.6 0.3 1.4 1 0 0 1 1 1 0 Zinc-finger of nitric oxide synthase-interacting protein U-box PF04564.15 CBK23270.2 - 0.032 14.4 0.0 0.1 12.8 0.0 1.8 2 0 0 2 2 2 0 U-box domain zf-RING_11 PF17123.5 CBK23270.2 - 0.038 13.7 9.5 0.16 11.8 7.2 2.5 2 1 0 2 2 2 0 RING-like zinc finger zf-ANAPC11 PF12861.7 CBK23270.2 - 0.13 12.3 5.3 0.22 11.6 5.3 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.6 CBK23270.2 - 0.31 10.9 8.9 0.72 9.7 8.8 1.6 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain IBR PF01485.21 CBK23270.2 - 1.3 9.3 10.0 3.3 8.0 9.9 1.8 1 1 0 1 1 1 0 IBR domain, a half RING-finger domain HSP70 PF00012.20 CBK23272.2 - 7.1e-88 295.3 0.1 7.6e-81 272.1 0.0 2.0 2 0 0 2 2 2 2 Hsp70 protein MreB_Mbl PF06723.13 CBK23272.2 - 1.7e-13 50.1 0.1 1.7e-10 40.2 0.0 3.0 2 1 0 2 2 2 2 MreB/Mbl protein BcrAD_BadFG PF01869.20 CBK23272.2 - 0.049 13.1 0.1 5.7 6.4 0.0 2.2 2 0 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family UPF0160 PF03690.13 CBK23273.2 - 1.2e-121 406.3 0.0 1.4e-121 406.1 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0160) Q_salvage PF10343.9 CBK23273.2 - 0.09 12.3 0.0 0.15 11.6 0.0 1.3 1 0 0 1 1 1 0 Potential Queuosine, Q, salvage protein family Endonuclease_5 PF04493.14 CBK23274.2 - 1.4e-39 135.9 0.0 2.4e-39 135.1 0.0 1.2 1 1 0 1 1 1 1 Endonuclease V UvrC_HhH_N PF08459.11 CBK23274.2 - 0.0079 16.1 0.0 0.019 14.9 0.0 1.6 1 1 1 2 2 2 1 UvrC Helix-hairpin-helix N-terminal Ribosomal_L25p PF01386.19 CBK23275.2 - 4.5e-15 55.9 0.0 7.9e-15 55.1 0.0 1.4 1 0 0 1 1 1 1 Ribosomal L25p family Ribosomal_TL5_C PF14693.6 CBK23275.2 - 0.0002 21.7 0.0 0.00031 21.1 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein TL5, C-terminal domain Ribosomal_L15e PF00827.17 CBK23276.2 - 2.9e-80 268.5 8.4 2.2e-79 265.6 8.4 1.9 1 1 0 1 1 1 1 Ribosomal L15 Ribosomal_L16 PF00252.18 CBK23277.2 - 6.7e-41 139.4 0.2 9.4e-41 138.9 0.2 1.2 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e Malate_DH PF12434.8 CBK23277.2 - 0.19 11.8 0.0 0.19 11.8 0.0 1.7 2 0 0 2 2 2 0 Malate dehydrogenase enzyme Ribosomal_S16 PF00886.19 CBK23278.2 - 1.2e-24 86.1 0.0 1.6e-24 85.7 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S16 Ribosomal_L24e PF01246.20 CBK23279.2 - 1.3e-33 115.0 3.0 1.3e-33 115.0 3.0 1.8 2 0 0 2 2 2 1 Ribosomal protein L24e DUF2175 PF09943.9 CBK23279.2 - 0.13 12.5 0.5 0.13 12.5 0.5 2.9 2 1 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2175) TPT PF03151.16 CBK23280.2 - 2.4e-09 36.9 5.6 2.7e-09 36.8 5.6 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family UAA PF08449.11 CBK23280.2 - 2.4e-05 23.7 1.7 2.7e-05 23.5 1.7 1.2 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.20 CBK23280.2 - 2.7e-05 24.4 5.6 3.3e-05 24.1 5.6 1.1 1 0 0 1 1 1 1 EamA-like transporter family Mg_trans_NIPA PF05653.14 CBK23280.2 - 0.00074 18.7 3.9 0.00086 18.5 3.9 1.1 1 0 0 1 1 1 1 Magnesium transporter NIPA adh_short PF00106.25 CBK23281.2 - 1.8e-20 73.2 0.0 2.5e-20 72.8 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CBK23281.2 - 5.8e-12 45.7 0.0 7.8e-12 45.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 CBK23282.2 - 8.7e-17 61.2 0.1 1e-16 61.0 0.1 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CBK23282.2 - 3.1e-11 43.3 0.1 3.9e-11 43.0 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CBK23282.2 - 9e-07 29.0 0.1 1e-06 28.8 0.1 1.0 1 0 0 1 1 1 1 KR domain 2-Hacid_dh_C PF02826.19 CBK23282.2 - 0.00026 20.4 0.2 0.00029 20.2 0.2 1.3 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.18 CBK23282.2 - 0.0008 19.3 0.1 0.001 19.0 0.1 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.14 CBK23282.2 - 0.0023 17.5 0.1 0.0029 17.2 0.1 1.1 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Sacchrp_dh_NADP PF03435.18 CBK23282.2 - 0.043 14.1 0.0 0.051 13.8 0.0 1.1 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Epimerase PF01370.21 CBK23282.2 - 0.061 12.8 0.0 0.069 12.6 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 CBK23282.2 - 0.074 12.4 0.1 0.086 12.2 0.1 1.1 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase KinB_sensor PF16767.5 CBK23282.2 - 0.08 13.4 0.0 0.099 13.1 0.0 1.1 1 0 0 1 1 1 0 Sensor domain of alginate biosynthesis sensor protein KinB YjcB PF15940.5 CBK23282.2 - 0.14 12.4 0.0 0.19 11.9 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function Nuc_sug_transp PF04142.15 CBK23283.2 - 1.1e-91 307.3 24.1 1.3e-91 307.1 24.1 1.0 1 0 0 1 1 1 1 Nucleotide-sugar transporter EamA PF00892.20 CBK23283.2 - 0.00018 21.7 37.4 0.0023 18.1 10.0 2.5 2 1 0 2 2 2 2 EamA-like transporter family TPT PF03151.16 CBK23283.2 - 0.0045 16.4 13.0 0.0045 16.4 13.0 2.3 1 1 1 2 2 2 2 Triose-phosphate Transporter family Orthopox_A47 PF06334.11 CBK23283.2 - 0.086 12.1 1.5 0.93 8.7 0.1 2.2 1 1 1 2 2 2 0 Orthopoxvirus A47 protein TM_helix PF05552.12 CBK23283.2 - 7.7 6.6 14.8 0.57 10.2 2.9 2.8 2 0 0 2 2 2 0 Conserved TM helix ELMO_CED12 PF04727.13 CBK23284.2 - 5.8e-21 75.4 0.0 2.9e-20 73.1 0.0 2.0 2 0 0 2 2 2 1 ELMO/CED-12 family RhoGAP PF00620.27 CBK23284.2 - 1e-05 25.4 0.0 1.9e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 RhoGAP domain Dor1 PF04124.12 CBK23285.2 - 1.7e-23 82.9 5.2 2.5e-23 82.3 5.2 1.2 1 0 0 1 1 1 1 Dor1-like family DUF812 PF05667.11 CBK23285.2 - 0.0016 17.4 3.7 0.065 12.1 0.6 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF812) SKA2 PF16740.5 CBK23285.2 - 0.0052 16.5 1.8 0.0084 15.9 0.6 1.9 1 1 0 1 1 1 1 Spindle and kinetochore-associated protein 2 Helicase_C PF00271.31 CBK23286.2 - 1.9e-12 47.5 0.1 6e-12 45.9 0.0 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain HA2 PF04408.23 CBK23286.2 - 4.5e-05 23.7 0.0 9.3e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 Helicase associated domain (HA2) DEAD PF00270.29 CBK23286.2 - 0.0018 18.1 0.5 0.0066 16.2 0.5 1.9 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_29 PF13555.6 CBK23286.2 - 0.1 12.3 0.0 0.26 11.1 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.27 CBK23286.2 - 0.12 12.9 0.0 0.29 11.6 0.0 1.6 1 0 0 1 1 1 0 ABC transporter AAA_23 PF13476.6 CBK23286.2 - 0.12 12.9 0.0 0.21 12.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain ResIII PF04851.15 CBK23286.2 - 0.13 12.3 0.0 0.29 11.1 0.0 1.7 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit zf-CCCH PF00642.24 CBK23287.2 - 5.7e-08 32.5 0.8 5.7e-08 32.5 0.8 2.0 2 0 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 CBK23287.2 - 1.2e-07 31.6 3.2 1.2e-07 31.6 3.2 1.8 2 0 0 2 2 2 1 Zinc finger domain zf-CCCH_4 PF18044.1 CBK23287.2 - 1.2e-07 31.3 0.9 2.2e-07 30.5 0.9 1.4 1 0 0 1 1 1 1 CCCH-type zinc finger Torus PF16131.5 CBK23287.2 - 0.00021 22.0 0.1 0.00069 20.3 0.1 1.9 1 0 0 1 1 1 1 Torus domain zf-CCCH_2 PF14608.6 CBK23287.2 - 0.026 15.0 0.9 0.07 13.6 0.9 1.8 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger Tti2 PF10521.9 CBK23287.2 - 0.073 12.6 0.5 0.72 9.3 0.0 2.5 2 0 0 2 2 2 0 Tti2 family DUF4325 PF14213.6 CBK23289.2 - 0.084 12.6 0.1 0.093 12.5 0.1 1.1 1 0 0 1 1 1 0 STAS-like domain of unknown function (DUF4325) DDHD PF02862.17 CBK23293.2 - 0.074 13.2 0.1 0.093 12.9 0.1 1.1 1 0 0 1 1 1 0 DDHD domain AdoHcyase PF05221.17 CBK23294.2 - 5.9e-129 429.5 0.0 6.6e-129 429.3 0.0 1.0 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD PF00670.21 CBK23294.2 - 8.5e-79 263.3 5.5 1.2e-78 262.8 5.5 1.2 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.19 CBK23294.2 - 4e-08 32.8 0.8 7e-08 32.0 0.3 1.6 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain THF_DHG_CYH_C PF02882.19 CBK23294.2 - 0.0011 18.3 3.9 0.0055 16.0 3.9 1.9 1 1 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain NAD_binding_7 PF13241.6 CBK23294.2 - 0.0011 19.3 1.1 0.0029 18.0 1.1 1.6 1 0 0 1 1 1 1 Putative NAD(P)-binding Shikimate_DH PF01488.20 CBK23294.2 - 0.0021 18.1 0.5 0.0049 16.9 0.5 1.6 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase ELFV_dehydrog PF00208.21 CBK23294.2 - 0.0064 16.2 1.1 0.073 12.8 1.3 2.5 1 1 1 2 2 2 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase TrkA_N PF02254.18 CBK23294.2 - 0.016 15.4 0.6 0.046 14.0 0.6 1.8 1 1 0 1 1 1 0 TrkA-N domain IlvN PF07991.12 CBK23294.2 - 0.024 14.2 0.2 0.041 13.5 0.2 1.4 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain Pkinase PF00069.25 CBK23295.2 - 1.7e-76 257.1 0.0 2.7e-76 256.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBK23295.2 - 3.7e-34 118.2 0.0 5.9e-34 117.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CBK23295.2 - 1.4e-07 31.1 0.0 2.7e-05 23.6 0.0 2.2 1 1 1 2 2 2 2 Kinase-like Kdo PF06293.14 CBK23295.2 - 1.3e-05 24.7 0.0 0.00017 21.0 0.0 2.1 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 CBK23295.2 - 0.0054 15.6 0.0 0.0086 14.9 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Ste5_C PF12194.8 CBK23295.2 - 0.0087 16.0 0.7 0.015 15.3 0.7 1.4 1 0 0 1 1 1 1 Protein kinase Fus3-binding Pox_ser-thr_kin PF05445.11 CBK23295.2 - 0.026 13.5 0.0 0.05 12.6 0.0 1.5 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase APH PF01636.23 CBK23295.2 - 0.028 14.3 0.0 0.091 12.7 0.0 1.7 1 1 1 2 2 2 0 Phosphotransferase enzyme family Rtf2 PF04641.12 CBK23296.2 - 7.4e-45 153.3 1.4 8.9e-45 153.1 1.4 1.0 1 0 0 1 1 1 1 Rtf2 RING-finger Prok-RING_1 PF14446.6 CBK23296.2 - 2.6 8.0 7.3 0.3 11.1 1.1 2.4 1 1 1 2 2 2 0 Prokaryotic RING finger family 1 Mid2 PF04478.12 CBK23297.2 - 0.099 12.5 0.1 0.23 11.3 0.1 1.6 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor CTP_transf_1 PF01148.20 CBK23298.2 - 6.6e-61 206.4 20.4 1.1e-60 205.7 20.4 1.3 1 0 0 1 1 1 1 Cytidylyltransferase family Holin_BhlA PF10960.8 CBK23298.2 - 1.8 8.6 3.8 0.76 9.8 0.4 2.2 2 0 0 2 2 2 0 BhlA holin family Rcd1 PF04078.13 CBK23299.2 - 1.3e-09 37.8 0.7 1.6e-09 37.4 0.7 1.2 1 0 0 1 1 1 1 Cell differentiation family, Rcd1-like Myosin_head PF00063.21 CBK23300.2 - 1.5e-205 684.4 0.0 2.4e-205 683.8 0.0 1.3 1 1 0 1 1 1 1 Myosin head (motor domain) WW PF00397.26 CBK23300.2 - 3.9e-06 26.9 2.6 8.4e-06 25.8 2.6 1.6 1 0 0 1 1 1 1 WW domain Myosin_N PF02736.19 CBK23300.2 - 1.4e-05 24.8 1.8 2.9e-05 23.8 1.8 1.6 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain AAA_22 PF13401.6 CBK23300.2 - 0.052 13.8 0.0 0.54 10.5 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 CBK23300.2 - 0.086 13.2 0.0 0.27 11.6 0.0 1.8 1 0 0 1 1 1 0 AAA ATPase domain TPT PF03151.16 CBK23301.2 - 3.7e-36 124.9 24.9 4.2e-36 124.8 24.9 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 CBK23301.2 - 1.9e-11 44.3 31.7 2.9e-09 37.2 12.0 2.1 2 0 0 2 2 2 2 EamA-like transporter family UAA PF08449.11 CBK23301.2 - 1.5e-08 34.2 25.5 2.4e-08 33.6 25.5 1.3 1 0 0 1 1 1 1 UAA transporter family DNA_ligase_A_C PF04679.15 CBK23302.2 - 1.6e-20 73.6 0.0 2.9e-20 72.7 0.0 1.4 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region DNA_ligase_A_M PF01068.21 CBK23302.2 - 1.1e-16 61.1 0.0 1.8e-16 60.4 0.0 1.3 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_OB_2 PF14743.6 CBK23302.2 - 0.0011 18.9 0.2 0.83 9.7 0.0 2.3 2 0 0 2 2 2 2 DNA ligase OB-like domain RNA_ligase PF09414.10 CBK23302.2 - 0.0037 17.6 0.0 0.0065 16.8 0.0 1.4 1 0 0 1 1 1 1 RNA ligase mRNA_cap_enzyme PF01331.19 CBK23302.2 - 0.14 12.0 0.0 3.5 7.4 0.0 2.2 1 1 0 1 1 1 0 mRNA capping enzyme, catalytic domain Cnd1 PF12717.7 CBK23303.2 - 1.9e-16 60.5 1.0 2.3e-16 60.3 1.0 1.1 1 0 0 1 1 1 1 non-SMC mitotic condensation complex subunit 1 Nipped-B_C PF12830.7 CBK23303.2 - 2.4e-08 34.1 0.6 3.2e-07 30.5 0.6 2.0 1 1 1 2 2 2 2 Sister chromatid cohesion C-terminus Adaptin_N PF01602.20 CBK23303.2 - 0.00018 20.2 1.8 0.00021 20.0 1.8 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Cnd3 PF12719.7 CBK23303.2 - 0.0021 17.3 1.7 0.0073 15.5 1.7 2.0 1 1 0 1 1 1 1 Nuclear condensing complex subunits, C-term domain HEAT_2 PF13646.6 CBK23303.2 - 0.027 14.9 0.0 0.076 13.4 0.0 1.6 1 1 0 1 1 1 0 HEAT repeats RTP1_C1 PF10363.9 CBK23303.2 - 0.083 13.1 0.3 0.16 12.2 0.2 1.5 1 1 0 1 1 1 0 Required for nuclear transport of RNA pol II C-terminus 1 Vac14_Fab1_bd PF12755.7 CBK23303.2 - 0.18 12.5 1.8 1.6 9.3 0.4 2.2 1 1 1 2 2 2 0 Vacuolar 14 Fab1-binding region Ribosomal_L7Ae PF01248.26 CBK23304.2 - 1.2e-27 95.5 0.1 1.4e-27 95.2 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family PELOTA_1 PF15608.6 CBK23304.2 - 0.00091 19.1 0.0 0.0013 18.6 0.0 1.3 1 0 0 1 1 1 1 PELOTA RNA binding domain RNase_P_pop3 PF08228.11 CBK23304.2 - 0.0011 19.1 0.1 0.0012 18.9 0.1 1.1 1 0 0 1 1 1 1 RNase P subunit Pop3 YadA_stalk PF05662.14 CBK23304.2 - 0.073 13.5 0.1 6.7 7.2 0.1 2.2 2 0 0 2 2 2 0 Coiled stalk of trimeric autotransporter adhesin Adenosine_kin PF04008.14 CBK23304.2 - 0.083 12.7 0.0 0.1 12.4 0.0 1.2 1 0 0 1 1 1 0 Adenosine specific kinase DUF2229 PF09989.9 CBK23304.2 - 0.15 11.7 0.1 0.3 10.7 0.1 1.5 1 1 1 2 2 2 0 CoA enzyme activase uncharacterised domain (DUF2229) MFS_1 PF07690.16 CBK23305.2 - 4.8e-08 32.3 16.3 4.8e-08 32.3 16.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 CBK23305.2 - 0.00022 20.2 3.1 0.00022 20.2 3.1 2.5 2 1 0 2 2 2 1 Sugar (and other) transporter MFS_1_like PF12832.7 CBK23305.2 - 0.0055 15.6 9.3 0.0037 16.2 8.1 1.4 1 1 0 1 1 1 1 MFS_1 like family ROK PF00480.20 CBK23306.2 - 4.4e-28 98.6 0.0 6.5e-28 98.0 0.0 1.2 1 0 0 1 1 1 1 ROK family UPF0180 PF03698.13 CBK23306.2 - 0.025 14.8 0.0 0.068 13.3 0.0 1.9 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0180) Dpy-30 PF05186.13 CBK23307.2 - 8.5e-19 67.0 0.1 1.1e-18 66.6 0.1 1.2 1 0 0 1 1 1 1 Dpy-30 motif RIIa PF02197.17 CBK23307.2 - 0.012 15.2 0.0 0.019 14.6 0.0 1.3 1 0 0 1 1 1 0 Regulatory subunit of type II PKA R-subunit zf-RING_2 PF13639.6 CBK23308.2 - 2.1e-14 53.5 5.6 3.6e-14 52.8 5.6 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 CBK23308.2 - 2.4e-11 43.2 3.3 2.4e-11 43.2 3.3 2.3 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 CBK23308.2 - 1e-10 41.3 5.5 1.8e-10 40.5 5.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CBK23308.2 - 3.2e-09 36.7 3.9 5.3e-09 35.9 1.0 2.3 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4 PF00097.25 CBK23308.2 - 4.3e-09 36.1 5.1 8e-09 35.2 5.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CBK23308.2 - 1.3e-08 34.6 3.5 2.2e-08 33.9 3.5 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.7 CBK23308.2 - 1.2e-07 31.9 7.7 4.5e-07 30.1 7.7 1.9 1 1 0 1 1 1 1 RING-H2 zinc finger domain Prok-RING_4 PF14447.6 CBK23308.2 - 4.7e-06 26.4 6.4 0.00013 21.7 3.0 2.3 1 1 1 2 2 2 2 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 CBK23308.2 - 6.9e-06 25.8 3.1 1.3e-05 25.0 3.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 CBK23308.2 - 0.00011 22.2 5.4 0.00014 22.0 3.7 2.0 2 1 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-ANAPC11 PF12861.7 CBK23308.2 - 0.00083 19.4 2.6 0.00083 19.4 2.6 2.1 2 1 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_ribbon_17 PF17120.5 CBK23308.2 - 0.0011 18.5 3.4 0.0021 17.7 3.4 1.4 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type FANCL_C PF11793.8 CBK23308.2 - 0.0015 18.6 4.8 0.036 14.2 4.8 2.4 1 1 0 1 1 1 1 FANCL C-terminal domain YlaC PF10777.9 CBK23308.2 - 0.0025 17.7 0.9 0.0037 17.1 0.9 1.2 1 0 0 1 1 1 1 Inner membrane protein YlaC Prok-RING_1 PF14446.6 CBK23308.2 - 0.0029 17.5 3.7 0.056 13.4 0.8 2.5 2 0 0 2 2 2 1 Prokaryotic RING finger family 1 Rad50_zn_hook PF04423.14 CBK23308.2 - 0.0047 16.7 0.1 1.3 8.9 0.0 2.4 2 0 0 2 2 2 1 Rad50 zinc hook motif zf-Nse PF11789.8 CBK23308.2 - 0.0082 15.9 3.1 0.02 14.7 3.1 1.7 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit Zf_RING PF16744.5 CBK23308.2 - 0.021 14.9 2.3 0.047 13.8 2.3 1.5 1 1 0 1 1 1 0 KIAA1045 RING finger Rtf2 PF04641.12 CBK23308.2 - 0.052 12.9 1.0 0.83 9.0 0.9 2.0 1 1 1 2 2 2 0 Rtf2 RING-finger PHD PF00628.29 CBK23308.2 - 0.06 13.2 3.9 0.12 12.3 3.9 1.5 1 0 0 1 1 1 0 PHD-finger zf-RING_4 PF14570.6 CBK23308.2 - 0.16 11.8 4.8 0.32 10.8 4.8 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_6 PF14835.6 CBK23308.2 - 0.28 11.1 2.7 5.1 7.1 0.7 2.3 1 1 1 2 2 2 0 zf-RING of BARD1-type protein RINGv PF12906.7 CBK23308.2 - 0.3 11.3 3.6 0.76 9.9 3.6 1.7 1 1 0 1 1 1 0 RING-variant domain FYVE PF01363.21 CBK23308.2 - 0.31 11.2 3.4 1.2 9.4 3.4 1.9 1 1 0 1 1 1 0 FYVE zinc finger zf-RING-like PF08746.11 CBK23308.2 - 0.38 11.1 3.9 1.4 9.3 3.8 2.0 1 1 1 2 2 2 0 RING-like domain zf-C3H2C3 PF17122.5 CBK23308.2 - 5 7.2 9.6 2.5 8.2 4.5 2.6 2 1 0 2 2 2 0 Zinc-finger PQ-loop PF04193.14 CBK23309.2 - 1.2e-24 85.9 14.8 4.7e-15 55.1 1.5 3.2 2 1 1 3 3 3 2 PQ loop repeat SAP PF02037.27 CBK23310.2 - 9.3e-10 38.0 0.0 1.5e-09 37.4 0.0 1.4 1 0 0 1 1 1 1 SAP domain zf-C3HC4_2 PF13923.6 CBK23310.2 - 1e-09 38.1 9.5 1e-09 38.1 9.5 3.0 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 CBK23310.2 - 2.9e-09 36.6 10.6 4.1e-09 36.2 7.9 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.6 CBK23310.2 - 6e-09 35.6 2.9 1.4e-08 34.5 2.9 1.6 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-RING_2 PF13639.6 CBK23310.2 - 4.2e-08 33.4 12.2 1.7e-07 31.4 9.3 2.6 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.25 CBK23310.2 - 9.4e-08 31.8 14.6 1e-07 31.7 10.0 2.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CBK23310.2 - 2.9e-07 30.3 13.6 2.9e-07 30.3 9.8 2.4 2 0 0 2 2 2 1 zinc-RING finger domain zf-rbx1 PF12678.7 CBK23310.2 - 1.5e-06 28.4 4.7 1.5e-06 28.4 4.7 2.5 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 CBK23310.2 - 1.1e-05 25.4 2.8 1.1e-05 25.4 2.8 3.2 3 1 1 4 4 4 1 RING-type zinc-finger Rtf2 PF04641.12 CBK23310.2 - 1.7e-05 24.3 2.5 4.3e-05 23.0 0.9 2.0 1 1 1 2 2 2 1 Rtf2 RING-finger Prok-RING_4 PF14447.6 CBK23310.2 - 0.00014 21.6 12.4 0.00044 20.0 7.8 2.5 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 U-box PF04564.15 CBK23310.2 - 0.00035 20.7 0.0 0.00075 19.6 0.0 1.6 1 0 0 1 1 1 1 U-box domain zf-RING_4 PF14570.6 CBK23310.2 - 0.011 15.5 6.3 0.011 15.5 6.3 2.3 2 1 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.6 CBK23310.2 - 0.019 15.1 16.3 0.021 15.0 9.8 2.9 3 1 0 3 3 2 0 zinc finger of C3HC4-type, RING zf-ANAPC11 PF12861.7 CBK23310.2 - 0.026 14.6 3.8 0.03 14.4 2.2 2.0 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger Det1 PF09737.9 CBK23310.2 - 0.065 12.3 0.1 0.089 11.8 0.1 1.1 1 0 0 1 1 1 0 De-etiolated protein 1 Det1 zf-RING_10 PF16685.5 CBK23310.2 - 0.077 13.1 4.4 0.25 11.5 4.4 1.9 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-Nse PF11789.8 CBK23310.2 - 0.27 11.1 8.0 0.12 12.2 4.8 2.1 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit Zn-C2H2_12 PF18112.1 CBK23310.2 - 0.31 11.6 10.4 0.43 11.1 0.2 3.4 3 0 0 3 3 3 0 Autophagy receptor zinc finger-C2H2 domain Prok-RING_1 PF14446.6 CBK23310.2 - 0.89 9.5 9.1 8 6.5 0.1 3.5 3 0 0 3 3 3 0 Prokaryotic RING finger family 1 zf-Di19 PF05605.12 CBK23310.2 - 1.5 9.2 11.2 49 4.3 0.2 3.6 2 1 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-CHY PF05495.12 CBK23310.2 - 1.8 9.1 8.0 2.7 8.5 3.5 2.5 2 0 0 2 2 2 0 CHY zinc finger zf-RING_11 PF17123.5 CBK23310.2 - 1.8 8.4 7.0 5.1 6.9 7.0 1.9 1 0 0 1 1 1 0 RING-like zinc finger DZR PF12773.7 CBK23310.2 - 4.2 7.5 11.4 0.32 11.1 4.1 2.6 2 1 0 2 2 2 0 Double zinc ribbon CPSase_L_D2 PF02786.17 CBK23311.2 - 2.1e-76 256.1 0.0 4.2e-76 255.1 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain PYC_OADA PF02436.18 CBK23311.2 - 2.5e-66 223.2 0.0 4.1e-66 222.5 0.0 1.4 1 0 0 1 1 1 1 Conserved carboxylase domain Biotin_carb_N PF00289.22 CBK23311.2 - 3.2e-40 137.1 0.4 8.3e-40 135.8 0.2 1.8 2 0 0 2 2 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 CBK23311.2 - 3.4e-31 107.5 0.0 1e-30 106.0 0.0 1.9 2 0 0 2 2 1 1 Biotin carboxylase C-terminal domain HMGL-like PF00682.19 CBK23311.2 - 1.9e-27 96.5 0.0 3.8e-27 95.5 0.0 1.4 1 0 0 1 1 1 1 HMGL-like Biotin_lipoyl PF00364.22 CBK23311.2 - 3.6e-17 62.0 3.8 1.2e-16 60.3 3.5 2.0 2 0 0 2 2 2 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.13 CBK23311.2 - 5e-12 45.8 0.0 1.3e-11 44.4 0.0 1.6 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus Biotin_lipoyl_2 PF13533.6 CBK23311.2 - 1.8e-10 40.4 0.1 0.00019 21.2 0.0 2.6 1 1 1 2 2 2 2 Biotin-lipoyl like ATP-grasp PF02222.22 CBK23311.2 - 5.3e-08 32.6 0.0 1.2e-07 31.4 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.14 CBK23311.2 - 8.1e-07 29.2 0.0 1.7e-06 28.2 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain RimK PF08443.11 CBK23311.2 - 8.3e-06 25.5 0.0 2.3e-05 24.1 0.0 1.8 2 0 0 2 2 2 1 RimK-like ATP-grasp domain HlyD_D23 PF16576.5 CBK23311.2 - 0.00052 19.3 1.9 0.21 10.8 0.4 3.0 2 1 1 3 3 3 2 Barrel-sandwich domain of CusB or HlyD membrane-fusion ATPgrasp_ST PF14397.6 CBK23311.2 - 0.0075 15.6 0.0 0.016 14.5 0.0 1.5 1 0 0 1 1 1 1 Sugar-transfer associated ATP-grasp HlyD_3 PF13437.6 CBK23311.2 - 0.0094 16.6 0.2 1.8 9.3 0.0 2.8 2 0 0 2 2 2 1 HlyD family secretion protein GARS_A PF01071.19 CBK23311.2 - 0.013 15.3 0.0 0.025 14.3 0.0 1.5 1 0 0 1 1 1 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATPgrasp_Ter PF15632.6 CBK23311.2 - 0.015 15.0 0.0 0.054 13.2 0.0 1.9 1 0 0 1 1 1 0 ATP-grasp in the biosynthetic pathway with Ter operon PTS_EIIA_1 PF00358.20 CBK23311.2 - 0.041 13.7 0.3 3.2 7.5 0.0 2.6 1 1 1 2 2 2 0 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 NQRA PF05896.11 CBK23311.2 - 0.064 12.7 1.6 0.11 11.8 1.6 1.4 1 0 0 1 1 1 0 Na(+)-translocating NADH-quinone reductase subunit A (NQRA) GCV_H PF01597.19 CBK23311.2 - 0.072 13.0 1.4 0.23 11.3 1.4 1.9 1 1 0 1 1 1 0 Glycine cleavage H-protein LRR_5 PF13306.6 CBK23312.2 - 0.082 12.9 2.1 0.15 12.0 2.1 1.4 1 0 0 1 1 1 0 BspA type Leucine rich repeat region (6 copies) Mito_fiss_reg PF05308.11 CBK23312.2 - 0.3 11.1 8.1 0.3 11.1 0.6 2.2 2 0 0 2 2 2 0 Mitochondrial fission regulator DUF1949 PF09186.11 CBK23314.2 - 0.009 15.9 0.0 0.014 15.2 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1949) SIS PF01380.22 CBK23316.2 - 0.054 13.4 0.0 0.092 12.6 0.0 1.3 1 0 0 1 1 1 0 SIS domain Lactamase_B_2 PF12706.7 CBK23318.2 - 0.0015 18.1 0.1 0.0024 17.4 0.0 1.4 2 0 0 2 2 2 1 Beta-lactamase superfamily domain VPS13_C PF16909.5 CBK23319.2 - 4e-53 179.8 7.5 2.8e-49 167.3 1.4 2.3 2 0 0 2 2 2 2 Vacuolar-sorting-associated 13 protein C-terminal ATG_C PF09333.11 CBK23319.2 - 0.00026 21.3 0.3 0.0031 17.8 0.0 2.8 4 0 0 4 4 4 1 Autophagy-related protein C terminal domain Methyltransf_15 PF09445.10 CBK23320.2 - 1.8e-33 115.5 0.0 2.6e-33 114.9 0.0 1.3 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Met_10 PF02475.16 CBK23320.2 - 4.2e-12 46.2 0.0 8.7e-12 45.2 0.0 1.4 1 1 0 1 1 1 1 Met-10+ like-protein Cons_hypoth95 PF03602.15 CBK23320.2 - 3.8e-06 26.7 0.0 5.8e-06 26.1 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_11 PF08241.12 CBK23320.2 - 0.00027 21.5 0.0 0.00069 20.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CBK23320.2 - 0.0009 19.9 0.0 0.0024 18.5 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain UPF0020 PF01170.18 CBK23320.2 - 0.0022 17.7 0.0 0.0028 17.4 0.0 1.2 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_18 PF12847.7 CBK23320.2 - 0.0022 17.9 0.1 0.0048 16.8 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain RrnaAD PF00398.20 CBK23320.2 - 0.02 14.0 0.0 0.03 13.4 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase DNA_methylase PF00145.17 CBK23320.2 - 0.064 12.6 0.0 0.1 11.9 0.0 1.2 1 0 0 1 1 1 0 C-5 cytosine-specific DNA methylase MTS PF05175.14 CBK23320.2 - 0.1 12.2 0.0 0.18 11.3 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Methyltr_RsmB-F PF01189.17 CBK23320.2 - 0.16 11.6 0.0 0.26 10.9 0.0 1.2 1 0 0 1 1 1 0 16S rRNA methyltransferase RsmB/F PRMT5 PF05185.16 CBK23320.2 - 0.18 11.6 0.0 0.36 10.7 0.0 1.4 1 0 0 1 1 1 0 PRMT5 arginine-N-methyltransferase LRR_4 PF12799.7 CBK23321.2 - 4.2e-34 116.0 16.8 1.2e-08 35.1 0.9 6.8 4 1 2 7 7 7 6 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CBK23321.2 - 5.2e-31 106.2 61.6 1.2e-08 34.6 2.7 6.7 2 1 7 9 9 9 8 Leucine rich repeat LRR_9 PF14580.6 CBK23321.2 - 1.5e-16 60.4 7.3 3.5e-05 23.4 0.0 4.1 1 1 3 4 4 4 4 Leucine-rich repeat LRR_1 PF00560.33 CBK23321.2 - 1.9e-07 30.7 23.9 3.3 8.6 0.2 10.2 11 0 0 11 11 11 2 Leucine Rich Repeat LRR_6 PF13516.6 CBK23321.2 - 5.2e-07 29.2 24.8 0.81 9.9 0.2 8.9 9 0 0 9 9 9 4 Leucine Rich repeat Myb_DNA-binding PF00249.31 CBK23322.2 - 2e-11 43.9 1.4 5.5e-11 42.5 1.4 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 CBK23322.2 - 2.2e-08 34.2 1.8 3.6e-08 33.5 0.3 2.1 2 0 0 2 2 2 1 Myb-like DNA-binding domain SANT_DAMP1_like PF16282.5 CBK23322.2 - 0.044 14.0 0.0 0.4 10.9 0.0 2.1 2 0 0 2 2 2 0 SANT/Myb-like domain of DAMP1 SLIDE PF09111.10 CBK23322.2 - 0.048 13.7 0.2 0.34 10.9 0.0 2.2 2 0 0 2 2 2 0 SLIDE ER-remodelling PF14755.6 CBK23322.2 - 0.12 12.7 0.0 0.18 12.1 0.0 1.2 1 0 0 1 1 1 0 Intracellular membrane remodeller Prenyltransf PF01255.19 CBK23323.2 - 7.1e-24 84.6 0.0 8.1e-24 84.4 0.0 1.0 1 0 0 1 1 1 1 Putative undecaprenyl diphosphate synthase TMP_2 PF06791.13 CBK23323.2 - 0.17 11.5 0.0 0.26 10.9 0.0 1.2 1 0 0 1 1 1 0 Prophage tail length tape measure protein Prenyltransf PF01255.19 CBK23324.2 - 5.1e-28 98.1 0.1 5.6e-28 98.0 0.1 1.2 1 0 0 1 1 1 1 Putative undecaprenyl diphosphate synthase AMMECR1 PF01871.17 CBK23325.2 - 9.1e-45 152.2 0.0 1.1e-44 152.0 0.0 1.1 1 0 0 1 1 1 1 AMMECR1 RabGAP-TBC PF00566.18 CBK23326.2 - 4e-13 49.5 0.9 4.8e-13 49.2 0.9 1.1 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Pox_F16 PF04708.12 CBK23326.2 - 0.058 12.8 0.0 0.24 10.8 0.0 1.9 3 0 0 3 3 3 0 Poxvirus F16 protein Aldose_epim PF01263.20 CBK23328.2 - 2.2e-18 66.6 0.1 2.8e-18 66.3 0.1 1.1 1 0 0 1 1 1 1 Aldose 1-epimerase Imm74 PF15603.6 CBK23328.2 - 0.018 15.2 0.1 0.032 14.4 0.1 1.3 1 0 0 1 1 1 0 Immunity protein 74 Pil1 PF13805.6 CBK23329.2 - 0.038 13.5 1.0 0.048 13.2 1.0 1.0 1 0 0 1 1 1 0 Eisosome component PIL1 HTH_57 PF18679.1 CBK23329.2 - 0.061 13.6 0.2 0.08 13.3 0.2 1.1 1 0 0 1 1 1 0 ThcOx helix turn helix domain Ist1 PF03398.14 CBK23330.2 - 2.2e-12 47.2 0.2 2.4e-12 47.1 0.2 1.0 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway RRM_2 PF04059.12 CBK23331.2 - 3.3e-28 97.8 0.1 4.3e-28 97.4 0.1 1.2 1 0 0 1 1 1 1 RNA recognition motif 2 Smg4_UPF3 PF03467.15 CBK23331.2 - 0.012 15.6 0.0 0.018 15.1 0.0 1.2 1 0 0 1 1 1 0 Smg-4/UPF3 family BRAP2 PF07576.12 CBK23331.2 - 0.1 12.8 0.1 0.19 12.0 0.1 1.3 1 0 0 1 1 1 0 BRCA1-associated protein 2 RRM_1 PF00076.22 CBK23331.2 - 0.14 12.0 0.0 0.38 10.6 0.0 1.7 1 1 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Collagen PF01391.18 CBK23331.2 - 0.43 10.4 8.8 3.9 7.3 8.8 2.1 1 1 0 1 1 1 0 Collagen triple helix repeat (20 copies) Coatomer_WDAD PF04053.14 CBK23332.2 - 0.017 14.2 0.0 0.2 10.6 0.0 2.2 1 1 0 1 1 1 0 Coatomer WD associated region DnaJ_C PF01556.18 CBK23334.2 - 3.9e-37 127.6 0.0 5.2e-37 127.2 0.0 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 CBK23334.2 - 2.1e-23 82.2 0.5 3.5e-23 81.5 0.5 1.4 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 CBK23334.2 - 5.4e-13 49.1 17.1 9.5e-13 48.3 17.1 1.4 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 CBK23334.2 - 0.33 10.9 15.3 0.29 11.1 1.4 3.2 1 1 2 3 3 3 0 Tryptophan RNA-binding attenuator protein inhibitory protein Pro_isomerase PF00160.21 CBK23335.2 - 1.6e-53 181.2 0.0 2e-53 180.9 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD NDUFA12 PF05071.16 CBK23336.2 - 5.8e-14 52.7 10.2 3.3e-13 50.3 10.2 2.1 1 1 0 1 1 1 1 NADH ubiquinone oxidoreductase subunit NDUFA12 Arabino_trans_N PF17689.1 CBK23337.2 - 0.14 12.3 0.1 0.33 11.1 0.0 1.6 2 0 0 2 2 2 0 Arabinosyltransferase concanavalin like domain Defensin_4 PF07936.12 CBK23338.2 - 0.06 13.2 0.1 0.42 10.5 0.1 2.3 2 0 0 2 2 2 0 Potassium-channel blocking toxin TSGP1 PF07771.11 CBK23338.2 - 0.095 12.9 0.6 0.19 11.9 0.6 1.4 1 0 0 1 1 1 0 Tick salivary peptide group 1 DUF1664 PF07889.12 CBK23339.2 - 3.5 7.7 35.5 2.4 8.2 8.5 4.6 1 1 5 6 6 6 0 Protein of unknown function (DUF1664) Filament PF00038.21 CBK23339.2 - 5.3 6.5 68.9 0.075 12.6 17.7 4.2 1 1 2 3 3 3 0 Intermediate filament protein DUF4677 PF15726.5 CBK23339.2 - 8 6.6 10.3 0.15 12.2 0.5 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF4677) Bromodomain PF00439.25 CBK23340.2 - 3.6e-21 75.0 0.1 8.8e-21 73.8 0.0 1.7 2 0 0 2 2 2 1 Bromodomain BET PF17035.5 CBK23340.2 - 1.6e-10 41.0 0.1 2.9e-10 40.1 0.1 1.5 1 0 0 1 1 1 1 Bromodomain extra-terminal - transcription regulation ATP-synt PF00231.19 CBK23340.2 - 0.07 12.8 0.0 0.29 10.8 0.0 1.7 1 1 1 2 2 2 0 ATP synthase Methyltransf_25 PF13649.6 CBK23341.2 - 2.8e-09 37.5 0.0 5.3e-09 36.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CBK23341.2 - 2.2e-08 34.7 0.0 5e-08 33.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 CBK23341.2 - 6e-07 29.1 0.0 9e-07 28.6 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_31 PF13847.6 CBK23341.2 - 4.7e-06 26.5 0.0 6.5e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 CBK23341.2 - 1.4e-05 25.0 0.0 2.2e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.11 CBK23341.2 - 0.00019 20.5 0.1 0.00031 19.8 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_12 PF08242.12 CBK23341.2 - 0.0006 20.5 0.0 0.0013 19.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain PRMT5 PF05185.16 CBK23341.2 - 0.00064 19.6 0.1 0.0013 18.6 0.1 1.5 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase CMAS PF02353.20 CBK23341.2 - 0.0011 18.4 0.0 0.002 17.5 0.0 1.4 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_24 PF13578.6 CBK23341.2 - 0.0016 19.5 0.0 0.0029 18.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 CBK23341.2 - 0.0055 16.3 0.1 0.0097 15.5 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase small domain PCMT PF01135.19 CBK23341.2 - 0.0056 16.5 0.1 0.0089 15.8 0.1 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) PRMT5_C PF17286.2 CBK23341.2 - 0.013 15.3 0.0 0.019 14.8 0.0 1.3 1 0 0 1 1 1 0 PRMT5 oligomerisation domain Methyltransf_4 PF02390.17 CBK23341.2 - 0.02 14.4 0.2 0.13 11.8 0.2 2.2 2 0 0 2 2 2 0 Putative methyltransferase Methyltransf_16 PF10294.9 CBK23341.2 - 0.038 13.7 0.0 0.054 13.2 0.0 1.2 1 0 0 1 1 1 0 Lysine methyltransferase Cons_hypoth95 PF03602.15 CBK23341.2 - 0.056 13.1 0.0 0.13 11.9 0.0 1.7 1 1 0 1 1 1 0 Conserved hypothetical protein 95 DHHC PF01529.20 CBK23342.2 - 7.1e-38 129.7 13.4 8.4e-38 129.5 13.4 1.1 1 0 0 1 1 1 1 DHHC palmitoyltransferase AA_permease_2 PF13520.6 CBK23342.2 - 0.0066 15.3 6.8 0.0085 15.0 6.8 1.0 1 0 0 1 1 1 1 Amino acid permease Metallophos PF00149.28 CBK23344.2 - 1.1e-09 39.1 1.2 1.5e-09 38.7 1.2 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 CBK23344.2 - 0.00036 20.8 0.0 0.0019 18.4 0.0 1.9 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Calreticulin PF00262.18 CBK23345.2 - 1.3e-132 442.1 0.1 1.7e-132 441.7 0.1 1.1 1 0 0 1 1 1 1 Calreticulin family PhoLip_ATPase_N PF16209.5 CBK23346.2 - 4.8e-21 74.2 3.4 4.8e-21 74.2 3.4 3.0 3 0 0 3 3 3 1 Phospholipid-translocating ATPase N-terminal PhoLip_ATPase_C PF16212.5 CBK23346.2 - 3.8e-12 46.5 0.5 3.8e-12 46.5 0.5 2.6 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal E1-E2_ATPase PF00122.20 CBK23346.2 - 1.7e-11 43.9 1.2 3.7e-11 42.9 0.0 2.0 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 CBK23346.2 - 1.2e-10 42.0 0.2 0.0002 21.7 0.0 3.6 4 0 0 4 4 4 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 CBK23346.2 - 2.7e-09 37.0 0.1 4.4e-08 33.1 0.0 2.6 2 1 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 CBK23346.2 - 4.8e-05 23.2 1.3 0.0073 16.1 0.1 2.8 2 1 1 3 3 3 1 haloacid dehalogenase-like hydrolase Citrus_P18 PF05520.11 CBK23346.2 - 0.038 13.7 0.0 0.093 12.4 0.0 1.6 1 0 0 1 1 1 0 Citrus tristeza virus P18 protein Germane PF10646.9 CBK23346.2 - 0.078 13.8 0.0 0.26 12.1 0.0 1.9 2 0 0 2 2 2 0 Sporulation and spore germination Herpes_U47 PF05467.11 CBK23346.2 - 0.11 10.6 0.1 0.17 10.0 0.1 1.1 1 0 0 1 1 1 0 Herpesvirus glycoprotein U47 RRM_1 PF00076.22 CBK23347.2 - 7.2e-10 38.6 0.0 0.00037 20.2 0.0 2.8 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 CBK23347.2 - 6.5e-07 29.0 0.0 0.00089 18.8 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM PF05172.13 CBK23347.2 - 1.8e-05 24.7 0.0 0.33 10.9 0.0 2.6 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif RRM_occluded PF16842.5 CBK23347.2 - 0.0022 17.8 0.0 0.1 12.5 0.0 2.5 2 0 0 2 2 2 1 Occluded RNA-recognition motif Limkain-b1 PF11608.8 CBK23347.2 - 0.011 15.8 0.0 0.12 12.4 0.0 2.6 3 0 0 3 3 3 0 Limkain b1 DUF1866 PF08952.11 CBK23347.2 - 0.012 15.5 0.0 1.8 8.4 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1866) T4_deiodinase PF00837.17 CBK23347.2 - 0.11 11.8 0.1 0.22 10.8 0.1 1.4 1 0 0 1 1 1 0 Iodothyronine deiodinase EMC3_TMCO1 PF01956.16 CBK23347.2 - 0.15 11.8 0.5 0.24 11.1 0.5 1.3 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like LSM PF01423.22 CBK23348.2 - 1.4e-09 37.5 0.0 1.6e-09 37.3 0.0 1.1 1 0 0 1 1 1 1 LSM domain SHMT PF00464.19 CBK23349.2 - 2.4e-180 599.4 0.0 2.8e-180 599.1 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Beta_elim_lyase PF01212.21 CBK23349.2 - 0.0038 16.5 0.0 0.012 14.9 0.0 1.7 1 1 0 1 1 1 1 Beta-eliminating lyase Macro PF01661.21 CBK23349.2 - 0.018 15.0 0.0 0.039 14.0 0.0 1.6 1 0 0 1 1 1 0 Macro domain Taeniidae_ag PF05596.11 CBK23349.2 - 0.15 12.1 0.5 28 4.8 0.0 3.4 3 0 0 3 3 3 0 Taeniidae antigen Ribosomal_S3_C PF00189.20 CBK23350.2 - 8.3e-23 80.7 1.0 1.6e-22 79.8 1.0 1.5 1 0 0 1 1 1 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.17 CBK23350.2 - 6.7e-11 41.9 0.2 1.2e-10 41.0 0.2 1.5 1 0 0 1 1 1 1 KH domain UN_NPL4 PF11543.8 CBK23350.2 - 0.015 15.8 0.0 0.029 14.8 0.0 1.6 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 HSP70 PF00012.20 CBK23351.2 - 5.8e-07 28.1 0.0 5.8e-07 28.1 0.0 1.5 2 0 0 2 2 2 1 Hsp70 protein NT-C2 PF10358.9 CBK23351.2 - 0.022 14.5 0.0 0.06 13.1 0.0 1.7 1 0 0 1 1 1 0 N-terminal C2 in EEIG1 and EHBP1 proteins Delta_lysin PF05372.11 CBK23351.2 - 0.054 12.8 0.2 0.12 11.7 0.2 1.5 1 0 0 1 1 1 0 Delta lysin family Aquarius_N PF16399.5 CBK23352.2 - 1.1e-145 486.8 4.3 5.2e-145 484.6 4.3 1.9 1 1 0 1 1 1 1 Intron-binding protein aquarius N-terminus B56 PF01603.20 CBK23352.2 - 4.5e-98 328.9 1.6 8.1e-98 328.1 1.6 1.4 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) AAA_12 PF13087.6 CBK23352.2 - 1.8e-29 102.8 0.0 4e-29 101.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 CBK23352.2 - 1.7e-28 100.1 0.1 3.9e-28 99.0 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 CBK23352.2 - 6.4e-07 29.8 0.0 3.1e-06 27.6 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 CBK23352.2 - 2.6e-05 24.0 0.0 0.0044 16.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain UvrD_C_2 PF13538.6 CBK23352.2 - 0.0011 18.8 0.1 0.0029 17.4 0.1 1.7 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain ResIII PF04851.15 CBK23352.2 - 0.0012 18.9 0.0 0.0039 17.2 0.0 1.9 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit UvrD-helicase PF00580.21 CBK23352.2 - 0.0013 18.3 0.1 0.018 14.6 0.0 2.5 3 0 0 3 3 3 1 UvrD/REP helicase N-terminal domain AAA_16 PF13191.6 CBK23352.2 - 0.0049 17.3 3.3 0.19 12.1 0.0 3.6 3 0 0 3 3 3 1 AAA ATPase domain AAA PF00004.29 CBK23352.2 - 0.012 16.1 0.0 0.099 13.1 0.0 2.6 3 0 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 CBK23352.2 - 0.014 15.7 0.0 0.15 12.3 0.0 2.9 2 0 0 2 2 2 0 AAA domain PhoH PF02562.16 CBK23352.2 - 0.026 14.0 0.0 0.054 12.9 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein DEAD PF00270.29 CBK23352.2 - 0.053 13.3 0.0 0.85 9.4 0.0 2.2 2 0 0 2 2 2 0 DEAD/DEAH box helicase DUF2075 PF09848.9 CBK23352.2 - 0.072 12.3 0.0 0.21 10.8 0.0 1.8 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) RhoGAP PF00620.27 CBK23353.2 - 6.3e-13 48.8 0.0 1e-12 48.1 0.0 1.3 1 0 0 1 1 1 1 RhoGAP domain Exo_endo_phos PF03372.23 CBK23353.2 - 0.00018 21.1 0.0 0.00071 19.2 0.0 1.9 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DUF1336 PF07059.12 CBK23354.2 - 2.1e-12 47.6 0.0 2.5e-12 47.4 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1336) Nucleotid_trans PF03407.16 CBK23355.2 - 1.3e-20 74.3 3.0 2.5e-20 73.4 3.0 1.5 1 0 0 1 1 1 1 Nucleotide-diphospho-sugar transferase Glyco_transf_49 PF13896.6 CBK23359.2 - 1.6e-11 44.2 1.5 1.1e-06 28.2 0.3 2.6 1 1 1 2 2 2 2 Glycosyl-transferase for dystroglycan PyrI_C PF02748.15 CBK23359.2 - 0.19 11.6 4.0 0.22 11.5 1.1 2.3 2 0 0 2 2 2 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain Ribosomal_L7Ae PF01248.26 CBK23362.2 - 3e-21 75.0 0.6 5.2e-21 74.2 0.6 1.4 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.11 CBK23362.2 - 0.091 12.8 0.0 0.15 12.1 0.0 1.3 1 0 0 1 1 1 0 RNase P subunit Pop3 Efg1 PF10153.9 CBK23362.2 - 0.5 10.7 3.8 0.37 11.2 1.8 1.8 2 0 0 2 2 2 0 rRNA-processing protein Efg1 Glyco_transf_49 PF13896.6 CBK23363.2 - 7.7e-12 45.2 1.8 7.9e-07 28.7 0.3 2.4 1 1 1 2 2 2 2 Glycosyl-transferase for dystroglycan PyrI_C PF02748.15 CBK23363.2 - 0.13 12.2 4.0 0.17 11.8 1.1 2.3 2 0 0 2 2 2 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain DNA_pol_B_2 PF03175.13 CBK23364.2 - 2.8e-15 56.2 10.1 6e-15 55.1 10.1 1.6 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral Glyco_transf_49 PF13896.6 CBK23366.2 - 2.7e-09 36.8 2.9 9.4e-09 35.0 0.3 2.4 2 1 0 2 2 2 1 Glycosyl-transferase for dystroglycan FBA_1 PF07734.13 CBK23366.2 - 0.00063 19.7 0.5 0.0016 18.4 0.4 1.7 1 1 0 1 1 1 1 F-box associated OSK PF17182.4 CBK23366.2 - 0.021 14.0 1.4 0.025 13.8 0.2 1.7 2 0 0 2 2 2 0 OSK domain Ribosomal_L7Ae PF01248.26 CBK23367.2 - 3.9e-21 74.6 0.6 6.8e-21 73.8 0.6 1.4 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Efg1 PF10153.9 CBK23367.2 - 0.56 10.6 3.8 0.46 10.9 1.8 1.9 2 0 0 2 2 2 0 rRNA-processing protein Efg1 VPS13 PF16908.5 CBK23368.2 - 6.1e-16 58.9 0.3 8.5e-16 58.5 0.3 1.2 1 0 0 1 1 1 1 Vacuolar sorting-associated protein 13, N-terminal Surface_Ag_2 PF01617.17 CBK23368.2 - 0.068 12.6 0.1 0.089 12.2 0.1 1.1 1 0 0 1 1 1 0 Surface antigen HrcA PF01628.21 CBK23368.2 - 0.12 12.2 0.1 0.23 11.3 0.1 1.5 1 1 1 2 2 2 0 HrcA protein C terminal domain Ank_4 PF13637.6 CBK23369.2 - 1e-09 38.7 0.1 8.5e-07 29.4 0.0 3.5 2 1 1 3 3 3 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 CBK23369.2 - 3e-09 37.4 0.2 4.7e-07 30.3 0.0 2.8 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 CBK23369.2 - 0.00013 22.2 0.0 35 5.4 0.0 4.6 4 0 0 4 4 4 0 Ankyrin repeat Ank PF00023.30 CBK23369.2 - 0.00037 20.8 0.0 2.1 8.9 0.0 4.0 3 0 0 3 3 3 1 Ankyrin repeat Ank_5 PF13857.6 CBK23369.2 - 0.00067 19.9 0.0 1.3 9.5 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Oberon_cc PF16312.5 CBK23369.2 - 0.03 14.2 2.1 0.03 14.2 2.1 1.8 2 0 0 2 2 2 0 Coiled-coil region of Oberon Anp1 PF03452.14 CBK23369.2 - 0.19 11.1 2.2 0.38 10.1 2.2 1.7 1 1 0 1 1 1 0 Anp1 Fer2_3 PF13085.6 CBK23370.2 - 2.4e-32 111.2 0.0 4e-32 110.5 0.0 1.3 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer4_17 PF13534.6 CBK23370.2 - 1.8e-08 34.8 6.6 1.8e-08 34.8 6.6 2.1 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_8 PF13183.6 CBK23370.2 - 3.4e-08 33.8 7.8 3.4e-08 33.8 7.8 2.3 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_10 PF13237.6 CBK23370.2 - 7.4e-08 32.4 3.3 7.4e-08 32.4 3.3 1.9 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer2 PF00111.27 CBK23370.2 - 0.011 15.7 0.5 0.011 15.7 0.5 2.0 2 0 0 2 2 2 0 2Fe-2S iron-sulfur cluster binding domain Fer4_9 PF13187.6 CBK23370.2 - 0.011 15.9 7.3 0.011 15.9 7.3 2.4 2 1 0 2 2 2 0 4Fe-4S dicluster domain Fer4_7 PF12838.7 CBK23370.2 - 0.44 11.2 14.8 0.045 14.3 8.0 2.6 2 2 0 2 2 2 0 4Fe-4S dicluster domain Ribosomal_L44 PF00935.19 CBK23371.2 - 3.2e-32 110.8 13.1 3.2e-32 110.8 13.1 1.5 2 0 0 2 2 2 1 Ribosomal protein L44 NOB1_Zn_bind PF08772.11 CBK23371.2 - 0.018 15.2 1.8 0.018 15.2 1.8 1.9 1 1 0 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like Ribosomal_L33 PF00471.20 CBK23371.2 - 0.082 13.4 3.8 0.082 13.4 3.8 3.1 2 1 1 3 3 3 0 Ribosomal protein L33 HNH_5 PF14279.6 CBK23371.2 - 0.11 12.4 0.4 0.11 12.4 0.4 2.3 2 0 0 2 2 2 0 HNH endonuclease Ribosomal_L37ae PF01780.19 CBK23372.2 - 3.4e-40 136.0 9.8 4e-40 135.8 9.8 1.1 1 0 0 1 1 1 1 Ribosomal L37ae protein family DUF1451 PF07295.11 CBK23372.2 - 0.056 13.5 2.6 0.079 13.0 2.6 1.2 1 0 0 1 1 1 0 Zinc-ribbon containing domain zf_UBZ PF18439.1 CBK23372.2 - 0.1 12.2 1.2 13 5.5 0.2 2.4 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger Zn_Tnp_IS1595 PF12760.7 CBK23372.2 - 0.24 11.4 7.3 0.74 9.8 7.5 1.7 1 1 1 2 2 2 0 Transposase zinc-ribbon domain zf-BED PF02892.15 CBK23372.2 - 0.24 11.4 10.0 0.44 10.6 0.7 2.8 2 1 1 3 3 3 0 BED zinc finger Frataxin_Cyay PF01491.16 CBK23374.2 - 2.3e-27 95.2 0.3 3.2e-27 94.7 0.3 1.2 1 1 0 1 1 1 1 Frataxin-like domain TCTP PF00838.17 CBK23375.2 - 4.1e-27 95.6 14.0 5.5e-23 82.1 10.0 3.2 1 1 0 2 2 2 2 Translationally controlled tumour protein PG_binding_4 PF12229.8 CBK23375.2 - 0.067 13.5 0.3 0.12 12.6 0.2 1.6 1 1 1 2 2 2 0 Putative peptidoglycan binding domain SLATT_fungal PF18142.1 CBK23375.2 - 0.15 12.1 0.6 0.22 11.5 0.4 1.4 1 1 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain FRB_dom PF08771.11 CBK23375.2 - 0.57 10.6 3.8 0.62 10.5 1.6 1.6 1 1 1 2 2 2 0 FKBP12-rapamycin binding domain Pkinase PF00069.25 CBK23376.2 - 1.1e-52 179.1 0.0 1.5e-52 178.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBK23376.2 - 3.6e-28 98.6 0.0 5.7e-28 97.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase POLO_box PF00659.18 CBK23376.2 - 9.8e-20 70.5 0.0 5.4e-16 58.5 0.0 2.4 2 0 0 2 2 2 2 POLO box duplicated region Kinase-like PF14531.6 CBK23376.2 - 1.1e-07 31.5 0.0 1.6e-07 30.9 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 CBK23376.2 - 3.5e-05 22.8 0.0 6e-05 22.0 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase RIO1 PF01163.22 CBK23376.2 - 0.007 16.0 0.0 0.014 15.0 0.0 1.4 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 CBK23376.2 - 0.095 12.6 0.1 0.095 12.6 0.1 2.0 2 0 0 2 2 2 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 CBK23376.2 - 0.11 11.4 0.1 0.17 10.8 0.1 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Pkinase PF00069.25 CBK23377.2 - 0.0003 20.3 0.1 0.00041 19.8 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain Galactosyl_T PF01762.21 CBK23380.2 - 3.2e-33 115.2 0.0 5.2e-33 114.5 0.0 1.3 1 0 0 1 1 1 1 Galactosyltransferase Flp1_like PF16982.5 CBK23382.2 - 0.00055 19.3 0.5 0.00087 18.6 0.5 1.3 1 0 0 1 1 1 1 Putative Flagellin, Flp1-like, domain Thioredoxin PF00085.20 CBK23382.2 - 0.02 14.9 0.0 0.031 14.2 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin OST3_OST6 PF04756.13 CBK23382.2 - 0.059 12.7 0.0 0.067 12.5 0.0 1.0 1 0 0 1 1 1 0 OST3 / OST6 family, transporter family Wound_ind PF08186.11 CBK23382.2 - 0.16 12.5 2.1 0.46 10.9 1.6 2.1 2 1 0 2 2 2 0 Wound-inducible basic protein family Thioredoxin PF00085.20 CBK23383.2 - 1.4e-15 57.1 0.1 1e-10 41.5 0.1 2.5 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_6 PF13848.6 CBK23383.2 - 1e-06 28.8 2.3 2.4e-05 24.3 0.5 2.3 2 0 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_2 PF13098.6 CBK23383.2 - 0.043 14.3 0.6 1.5 9.3 0.1 2.8 3 0 0 3 3 3 0 Thioredoxin-like domain Sas10 PF09368.10 CBK23384.2 - 4.7e-25 87.9 6.5 4.7e-25 87.9 6.5 2.4 2 0 0 2 2 2 1 Sas10 C-terminal domain Sas10_Utp3 PF04000.15 CBK23384.2 - 6.6e-05 23.4 2.7 7.3e-05 23.3 0.0 2.5 3 0 0 3 3 3 1 Sas10/Utp3/C1D family SH3_9 PF14604.6 CBK23385.2 - 5.4e-16 58.2 0.2 1.1e-15 57.1 0.2 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 CBK23385.2 - 9.7e-15 53.9 0.1 1.9e-14 53.0 0.1 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 CBK23385.2 - 4.4e-12 45.5 0.0 8.7e-12 44.5 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain BAR PF03114.18 CBK23385.2 - 2.2e-07 30.8 8.8 5.9e-07 29.4 8.8 1.8 1 1 1 2 2 2 1 BAR domain BAR_3 PF16746.5 CBK23385.2 - 6.1e-05 22.8 4.5 9.6e-05 22.2 4.5 1.3 1 0 0 1 1 1 1 BAR domain of APPL family DUF885 PF05960.11 CBK23385.2 - 0.082 12.5 0.8 0.14 11.8 0.1 1.7 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF885) CENP-H PF05837.12 CBK23385.2 - 0.16 12.4 1.2 1.4 9.4 0.0 2.3 2 0 0 2 2 2 0 Centromere protein H (CENP-H) Rootletin PF15035.6 CBK23385.2 - 0.37 10.8 5.6 0.44 10.5 0.2 2.2 2 0 0 2 2 2 0 Ciliary rootlet component, centrosome cohesion TPR_MLP1_2 PF07926.12 CBK23385.2 - 0.47 10.5 3.7 5.6 7.0 0.8 2.4 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein PUF PF00806.19 CBK23386.2 - 2.2e-19 68.0 3.4 1.3e-05 24.6 0.2 5.3 5 0 0 5 5 5 4 Pumilio-family RNA binding repeat CPL PF08144.11 CBK23386.2 - 0.097 13.0 0.1 2.3 8.6 0.0 2.4 1 1 0 2 2 2 0 CPL (NUC119) domain TFIIA PF03153.13 CBK23386.2 - 0.1 12.6 22.0 0.18 11.7 22.0 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SPX PF03105.19 CBK23386.2 - 1.2 9.0 11.6 1.9 8.3 11.6 1.4 1 0 0 1 1 1 0 SPX domain Apt1 PF10351.9 CBK23386.2 - 2.1 7.1 5.1 3.2 6.5 5.1 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain Ndc1_Nup PF09531.10 CBK23386.2 - 2.3 6.8 13.9 3.5 6.2 13.9 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup eIF-5_eIF-2B PF01873.17 CBK23387.2 - 5.2e-33 113.4 0.8 6.1e-33 113.2 0.8 1.1 1 0 0 1 1 1 1 Domain found in IF2B/IF5 Lar_restr_allev PF14354.6 CBK23387.2 - 0.01 16.2 0.7 0.081 13.3 0.7 2.1 1 1 1 2 2 2 0 Restriction alleviation protein Lar TF_Zn_Ribbon PF08271.12 CBK23387.2 - 0.03 13.8 0.2 0.05 13.1 0.2 1.4 1 0 0 1 1 1 0 TFIIB zinc-binding Arc_trans_TRASH PF08394.10 CBK23387.2 - 0.55 10.6 5.1 0.87 10.0 0.3 2.8 1 1 1 2 2 2 0 Archaeal TRASH domain zinc_ribbon_6 PF14599.6 CBK23387.2 - 1.4 9.0 6.8 2.4 8.3 2.9 2.4 2 1 1 3 3 3 0 Zinc-ribbon DUF1682 PF07946.14 CBK23388.2 - 2.2e-37 129.0 0.1 4.9e-37 127.9 0.1 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF1682) DUF4090 PF13319.6 CBK23389.2 - 0.049 13.9 1.0 0.06 13.6 1.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4090) IATP PF04568.12 CBK23389.2 - 0.17 12.3 5.8 0.28 11.6 5.8 1.5 1 1 0 1 1 1 0 Mitochondrial ATPase inhibitor, IATP ACBP PF00887.19 CBK23390.2 - 8.6e-29 99.6 0.4 1e-28 99.4 0.4 1.0 1 0 0 1 1 1 1 Acyl CoA binding protein FERM_M PF00373.18 CBK23390.2 - 0.14 12.6 0.1 0.25 11.8 0.1 1.3 1 1 0 1 1 1 0 FERM central domain GTP_EFTU PF00009.27 CBK23391.2 - 1.5e-54 184.5 0.0 1.7e-54 184.3 0.0 1.1 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 CBK23391.2 - 0.0081 16.2 0.0 0.025 14.7 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase EFG_C PF00679.24 CBK23392.2 - 1.1e-15 57.4 0.1 4e-15 55.6 0.0 2.0 2 0 0 2 2 2 1 Elongation factor G C-terminus EFG_II PF14492.6 CBK23392.2 - 1.2e-09 38.1 0.0 2.8e-09 36.9 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_IV PF03764.18 CBK23392.2 - 0.00038 20.2 0.0 0.0017 18.1 0.0 2.1 3 0 0 3 3 3 1 Elongation factor G, domain IV SRP-alpha_N PF04086.13 CBK23392.2 - 0.00068 19.6 8.3 0.00068 19.6 8.3 1.8 3 0 0 3 3 2 1 Signal recognition particle, alpha subunit, N-terminal Apt1 PF10351.9 CBK23392.2 - 0.0091 14.9 6.3 0.012 14.4 6.3 1.3 1 0 0 1 1 1 1 Golgi-body localisation protein domain RF3_C PF16658.5 CBK23392.2 - 0.01 15.6 0.0 0.034 14.0 0.0 1.8 1 0 0 1 1 1 0 Class II release factor RF3, C-terminal domain CPSF100_C PF13299.6 CBK23392.2 - 0.014 15.5 5.7 8.7 6.5 6.2 2.8 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal Spt20 PF12090.8 CBK23392.2 - 0.025 14.2 14.4 0.045 13.4 14.4 1.5 1 1 0 1 1 1 0 Spt20 family Smg8_Smg9 PF10220.9 CBK23392.2 - 0.082 11.2 6.0 0.11 10.7 6.0 1.1 1 0 0 1 1 1 0 Smg8_Smg9 Presenilin PF01080.17 CBK23392.2 - 0.15 10.8 12.7 0.24 10.1 12.7 1.2 1 0 0 1 1 1 0 Presenilin Zip PF02535.22 CBK23392.2 - 0.16 11.1 1.6 0.22 10.7 1.6 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter SLC12 PF03522.15 CBK23392.2 - 0.36 9.8 7.4 0.65 9.0 7.4 1.4 1 0 0 1 1 1 0 Solute carrier family 12 Miga PF10265.9 CBK23392.2 - 0.78 8.6 10.0 1.7 7.5 10.0 1.5 1 0 0 1 1 1 0 Mitoguardin Kei1 PF08552.11 CBK23392.2 - 2.7 7.8 5.9 23 4.8 6.0 2.1 2 0 0 2 2 2 0 Inositolphosphorylceramide synthase subunit Kei1 RAP1 PF07218.11 CBK23392.2 - 2.8 6.1 7.8 4.2 5.5 7.8 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) ALMT PF11744.8 CBK23392.2 - 4.1 6.1 7.6 6.4 5.5 7.6 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter Macoilin PF09726.9 CBK23392.2 - 5.1 5.5 15.2 8.1 4.9 15.2 1.2 1 0 0 1 1 1 0 Macoilin family NPR3 PF03666.13 CBK23392.2 - 8.5 5.0 13.9 15 4.2 13.9 1.4 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 ANAPC4_WD40 PF12894.7 CBK23393.2 - 0.078 13.3 0.0 8.2 6.8 0.0 2.9 2 1 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain DUF1349 PF07081.11 CBK23393.2 - 0.12 12.1 0.0 0.29 10.8 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1349) WD40 PF00400.32 CBK23394.2 - 2.7e-16 59.6 10.6 7.6e-08 32.9 0.4 6.2 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBK23394.2 - 1.3e-09 38.2 0.1 0.23 11.8 0.0 4.5 3 1 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 CBK23394.2 - 0.1 12.5 0.0 26 4.6 0.1 3.2 2 1 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A zf-C2HC5 PF06221.13 CBK23395.2 - 1.5e-09 37.7 9.0 2.4e-09 37.0 9.0 1.3 1 0 0 1 1 1 1 Putative zinc finger motif, C2HC5-type P_C PF06640.11 CBK23395.2 - 0.072 13.2 1.4 0.11 12.7 0.9 1.6 1 1 0 1 1 1 0 P protein C-terminus zf-ribbon_3 PF13248.6 CBK23395.2 - 0.083 12.3 1.7 0.17 11.3 1.7 1.5 1 0 0 1 1 1 0 zinc-ribbon domain TAF PF02969.17 CBK23396.2 - 7.7e-05 22.8 0.2 0.00016 21.7 0.2 1.5 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) Histone PF00125.24 CBK23396.2 - 0.067 13.5 0.2 0.15 12.4 0.2 1.6 1 0 0 1 1 1 0 Core histone H2A/H2B/H3/H4 ProRS-C_1 PF09180.11 CBK23397.2 - 6.8e-24 83.9 2.8 1.1e-23 83.2 2.0 1.9 2 0 0 2 2 2 1 Prolyl-tRNA synthetase, C-terminal tRNA-synt_2b PF00587.25 CBK23397.2 - 2.3e-17 63.5 0.0 3.7e-17 62.8 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 CBK23397.2 - 2.6e-15 56.3 0.4 1e-14 54.4 0.0 2.1 2 0 0 2 2 2 1 Anticodon binding domain DUF92 PF01940.16 CBK23398.2 - 6e-22 78.2 0.1 1.2e-21 77.2 0.0 1.5 1 1 1 2 2 2 1 Integral membrane protein DUF92 UMPH-1 PF05822.12 CBK23400.2 - 1.2e-70 237.8 0.7 1.5e-70 237.5 0.7 1.1 1 0 0 1 1 1 1 Pyrimidine 5'-nucleotidase (UMPH-1) HAD PF12710.7 CBK23400.2 - 0.0059 17.0 0.1 0.013 15.9 0.1 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase RRM_1 PF00076.22 CBK23401.2 - 2.2e-17 62.6 0.2 3.9e-17 61.8 0.0 1.5 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 CBK23401.2 - 1e-08 34.8 0.0 1.4e-08 34.4 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.8 CBK23401.2 - 0.0081 16.2 0.2 0.015 15.3 0.2 1.4 1 0 0 1 1 1 1 Limkain b1 RRM_occluded PF16842.5 CBK23401.2 - 0.058 13.3 0.0 0.1 12.5 0.0 1.3 1 0 0 1 1 1 0 Occluded RNA-recognition motif PI3K_1B_p101 PF10486.9 CBK23401.2 - 4.1 5.1 9.1 6 4.5 9.1 1.2 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Pkinase PF00069.25 CBK23402.2 - 2.4e-77 259.9 0.0 2.9e-77 259.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBK23402.2 - 1.1e-37 129.8 0.0 1.4e-37 129.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CBK23402.2 - 5.5e-06 25.9 0.0 3.2e-05 23.4 0.0 1.9 2 0 0 2 2 2 1 Kinase-like Pkinase_C PF00433.24 CBK23402.2 - 0.00023 21.8 0.6 0.00045 20.9 0.6 1.5 1 0 0 1 1 1 1 Protein kinase C terminal domain FTA2 PF13095.6 CBK23402.2 - 0.0087 15.7 0.2 0.39 10.3 0.0 2.4 3 0 0 3 3 3 1 Kinetochore Sim4 complex subunit FTA2 Haspin_kinase PF12330.8 CBK23402.2 - 0.14 11.0 0.0 0.2 10.5 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain DHHC PF01529.20 CBK23403.2 - 8.4e-32 110.1 12.5 8.4e-32 110.1 12.5 2.2 2 0 0 2 2 2 1 DHHC palmitoyltransferase Ank_2 PF12796.7 CBK23403.2 - 8.7e-11 42.3 0.2 4.5e-10 40.0 0.2 2.1 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CBK23403.2 - 1.4e-09 38.3 0.2 0.00016 22.1 0.1 2.7 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 CBK23403.2 - 3.3e-08 33.2 0.4 0.06 13.9 0.0 3.8 3 0 0 3 3 3 2 Ankyrin repeat Ank PF00023.30 CBK23403.2 - 7.7e-08 32.5 0.5 0.0029 18.0 0.1 2.9 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.6 CBK23403.2 - 0.00018 21.7 0.3 0.8 10.1 0.0 2.7 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ninjurin PF04923.12 CBK23403.2 - 0.033 14.1 1.6 0.069 13.1 1.6 1.5 1 0 0 1 1 1 0 Ninjurin Baculo_11_kDa PF06143.11 CBK23403.2 - 0.037 13.6 3.8 1.5 8.4 0.1 2.4 2 0 0 2 2 2 0 Baculovirus 11 kDa family Ribosomal_L40e PF01020.17 CBK23403.2 - 0.09 12.7 8.6 0.21 11.5 8.6 1.5 1 0 0 1 1 1 0 Ribosomal L40e family DUF898 PF05987.13 CBK23403.2 - 0.22 10.5 4.3 0.39 9.7 4.3 1.3 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF898) TctB PF07331.11 CBK23403.2 - 1.6 9.0 8.0 0.13 12.5 1.4 2.1 2 0 0 2 2 2 0 Tripartite tricarboxylate transporter TctB family RRM_1 PF00076.22 CBK23404.2 - 1.1e-18 66.8 1.0 3.7e-11 42.7 0.0 3.4 4 0 0 4 4 4 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Beach PF02138.18 CBK23405.2 - 6.4e-102 340.6 0.0 8.4e-102 340.2 0.0 1.2 1 0 0 1 1 1 1 Beige/BEACH domain WD40 PF00400.32 CBK23405.2 - 0.00022 21.9 0.2 0.17 12.8 0.1 3.1 2 0 0 2 2 2 2 WD domain, G-beta repeat DUF1748 PF08520.10 CBK23407.2 - 3.3e-09 36.5 0.0 4.5e-09 36.1 0.0 1.2 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1748) MRF_C1 PF13887.6 CBK23408.2 - 0.3 10.3 4.8 2.8 7.2 0.4 2.5 2 0 0 2 2 2 0 Myelin gene regulatory factor -C-terminal domain 1 ALMT PF11744.8 CBK23408.2 - 0.45 9.3 17.1 0.6 8.9 17.1 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter NOA36 PF06524.12 CBK23408.2 - 0.92 8.8 6.5 1.6 8.0 6.5 1.4 1 0 0 1 1 1 0 NOA36 protein DUF913 PF06025.12 CBK23408.2 - 1.7 7.5 14.3 1.1 8.2 12.3 1.5 1 1 0 1 1 1 0 Domain of Unknown Function (DUF913) Lebercilin PF15619.6 CBK23409.2 - 8.9e-05 22.2 24.3 0.0025 17.5 23.6 3.0 1 1 0 1 1 1 1 Ciliary protein causing Leber congenital amaurosis disease PRKG1_interact PF15898.5 CBK23409.2 - 0.0021 19.0 17.7 0.011 16.6 11.4 2.4 2 0 0 2 2 2 1 cGMP-dependent protein kinase interacting domain Spc7 PF08317.11 CBK23409.2 - 0.0042 16.0 17.3 0.0042 16.0 17.3 2.0 1 1 0 2 2 2 1 Spc7 kinetochore protein Methyltransf_31 PF13847.6 CBK23409.2 - 0.016 15.0 1.1 0.024 14.5 0.4 1.7 2 0 0 2 2 2 0 Methyltransferase domain DUF1090 PF06476.12 CBK23409.2 - 0.028 14.5 8.6 2.3 8.4 0.1 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1090) ATG16 PF08614.11 CBK23409.2 - 0.033 14.4 1.7 0.033 14.4 1.7 2.9 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) SPACA9 PF15120.6 CBK23409.2 - 0.034 13.9 8.0 0.065 13.0 8.0 1.5 1 0 0 1 1 1 0 Sperm acrosome-associated protein 9 TPR_MLP1_2 PF07926.12 CBK23409.2 - 0.093 12.8 26.0 0.12 12.4 18.1 2.4 1 1 2 3 3 3 0 TPR/MLP1/MLP2-like protein DUF3037 PF11236.8 CBK23409.2 - 0.11 12.9 2.3 0.34 11.4 0.0 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3037) SKA1 PF07160.12 CBK23409.2 - 0.12 12.2 10.3 3.2 7.5 8.1 2.2 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 1 CENP-K PF11802.8 CBK23409.2 - 0.14 11.7 15.6 0.72 9.4 15.6 1.9 1 1 0 1 1 1 0 Centromere-associated protein K YabA PF06156.13 CBK23409.2 - 0.15 12.7 18.6 1.7 9.3 0.4 3.2 1 1 2 3 3 3 0 Initiation control protein YabA MPS2 PF17060.5 CBK23409.2 - 0.22 10.7 13.0 0.036 13.3 3.0 2.3 1 1 1 2 2 2 0 Monopolar spindle protein 2 RTBV_P46 PF06216.11 CBK23409.2 - 0.33 9.8 1.7 0.52 9.1 1.7 1.2 1 0 0 1 1 1 0 Rice tungro bacilliform virus P46 protein DUF4201 PF13870.6 CBK23409.2 - 0.36 10.5 21.2 1 9.1 11.2 2.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) WD-3 PF09765.9 CBK23409.2 - 0.42 9.9 8.8 0.39 10.0 7.6 1.4 1 1 0 1 1 1 0 WD-repeat region Fib_alpha PF08702.10 CBK23409.2 - 0.54 10.4 14.3 1.5 9.0 7.1 2.2 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family DUF1664 PF07889.12 CBK23409.2 - 0.85 9.7 7.4 6.7 6.8 4.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) DUF724 PF05266.14 CBK23409.2 - 1.3 8.9 14.4 1.5 8.7 3.6 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF724) DUF4407 PF14362.6 CBK23409.2 - 2.7 7.2 18.1 60 2.8 18.1 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) GrpE PF01025.19 CBK23409.2 - 2.8 7.6 13.6 2 8.1 0.5 2.8 1 1 1 2 2 2 0 GrpE Jnk-SapK_ap_N PF09744.9 CBK23409.2 - 3.1 8.0 24.2 0.35 11.1 10.5 2.4 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 V_ATPase_I PF01496.19 CBK23409.2 - 3.3 5.5 12.3 4.7 5.0 12.3 1.3 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family FlaC_arch PF05377.11 CBK23409.2 - 4.2 7.8 10.1 4.8 7.7 0.3 3.2 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) FAM76 PF16046.5 CBK23409.2 - 4.8 6.4 10.7 11 5.2 10.5 1.8 1 1 0 1 1 1 0 FAM76 protein FapA PF03961.13 CBK23409.2 - 6.7 5.2 12.0 1.7 7.2 5.5 1.9 1 1 1 2 2 2 0 Flagellar Assembly Protein A APG6_N PF17675.1 CBK23409.2 - 6.9 7.2 30.0 2.8 8.5 7.8 3.1 1 1 1 2 2 2 0 Apg6 coiled-coil region LMBR1 PF04791.16 CBK23409.2 - 9.9 4.9 8.4 14 4.5 8.4 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein E1_dh PF00676.20 CBK23410.2 - 2.1e-90 302.7 0.1 2.6e-90 302.4 0.1 1.1 1 0 0 1 1 1 1 Dehydrogenase E1 component Ac76 PF05814.11 CBK23411.2 - 0.072 13.1 0.4 0.15 12.1 0.4 1.5 1 0 0 1 1 1 0 Orf76 (Ac76) TetR_C_37 PF18665.1 CBK23411.2 - 0.23 12.1 3.2 7.5 7.2 0.4 2.2 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain Metallophos PF00149.28 CBK23412.2 - 2.1e-23 83.9 0.0 2.8e-23 83.5 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Spt20 PF12090.8 CBK23412.2 - 0.0079 15.8 28.6 0.015 15.0 28.6 1.3 1 0 0 1 1 1 1 Spt20 family PepSY_TM PF03929.16 CBK23412.2 - 0.061 13.0 3.2 0.096 12.3 3.2 1.3 1 0 0 1 1 1 0 PepSY-associated TM region Roughex PF06020.11 CBK23412.2 - 0.098 11.7 6.8 0.14 11.2 6.8 1.2 1 0 0 1 1 1 0 Drosophila roughex protein EIIBC-GUT_N PF03612.14 CBK23412.2 - 0.39 10.4 5.6 0.72 9.6 5.6 1.5 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus Pex14_N PF04695.13 CBK23412.2 - 0.43 11.2 11.2 0.84 10.3 11.2 1.4 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF4175 PF13779.6 CBK23412.2 - 3.1 5.6 19.5 4.2 5.2 19.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) TFIIA PF03153.13 CBK23412.2 - 4 7.3 25.2 5.9 6.8 25.2 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Suf PF05843.14 CBK23412.2 - 4.8 7.1 13.5 7.4 6.5 13.5 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) TERB2 PF15101.6 CBK23412.2 - 6.2 6.8 12.9 10 6.1 12.9 1.3 1 0 0 1 1 1 0 Telomere-associated protein TERB2 HAT_KAT11 PF08214.11 CBK23413.2 - 2.4e-24 86.3 0.0 1.7e-23 83.5 0.0 1.9 2 0 0 2 2 2 1 Histone acetylation protein Bromodomain PF00439.25 CBK23413.2 - 1.2e-17 63.7 0.0 2.9e-17 62.5 0.0 1.7 1 0 0 1 1 1 1 Bromodomain PHD PF00628.29 CBK23413.2 - 0.0067 16.3 7.4 0.0067 16.3 7.4 3.5 3 0 0 3 3 3 1 PHD-finger Utp14 PF04615.13 CBK23415.2 - 1.1e-71 242.5 67.7 8.5e-71 239.6 67.7 2.0 1 1 0 1 1 1 1 Utp14 protein Peptidase_M18 PF02127.15 CBK23416.2 - 1.6e-135 452.3 0.0 1.8e-135 452.1 0.0 1.0 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Peptidase_M42 PF05343.14 CBK23416.2 - 3.3e-05 23.1 0.0 6e-05 22.2 0.0 1.4 1 0 0 1 1 1 1 M42 glutamyl aminopeptidase He_PIG PF05345.12 CBK23418.2 - 1.2e-06 28.6 4.3 0.00036 20.7 0.5 2.9 2 0 0 2 2 2 2 Putative Ig domain Stevor PF17410.2 CBK23418.2 - 0.00068 19.3 0.4 0.0017 18.0 0.4 1.6 1 0 0 1 1 1 1 Subtelomeric Variable Open Reading frame DUF4834 PF16118.5 CBK23418.2 - 0.0071 17.3 0.8 0.016 16.1 0.8 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4834) ECSCR PF15820.5 CBK23418.2 - 0.0084 15.9 0.5 0.02 14.7 0.5 1.6 1 0 0 1 1 1 1 Endothelial cell-specific chemotaxis regulator ASFV_J13L PF05568.11 CBK23418.2 - 0.014 15.2 0.5 0.014 15.2 0.5 1.8 2 0 0 2 2 2 0 African swine fever virus J13L protein DUF898 PF05987.13 CBK23418.2 - 0.071 12.2 0.0 0.12 11.3 0.0 1.3 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF898) EphA2_TM PF14575.6 CBK23418.2 - 0.2 12.6 2.1 0.46 11.4 2.1 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF5385 PF17359.2 CBK23418.2 - 0.62 9.6 5.3 0.96 9.0 5.3 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5385) Baculo_11_kDa PF06143.11 CBK23418.2 - 0.63 9.7 3.3 1.4 8.6 3.3 1.5 1 0 0 1 1 1 0 Baculovirus 11 kDa family TMIE PF16038.5 CBK23418.2 - 1.7 8.5 4.1 3.4 7.6 4.1 1.4 1 0 0 1 1 1 0 TMIE protein Ribosomal_L7Ae PF01248.26 CBK23419.2 - 3.1e-21 74.9 0.6 5.2e-21 74.2 0.6 1.4 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Efg1 PF10153.9 CBK23419.2 - 0.44 10.9 3.8 0.37 11.2 1.8 1.9 2 0 0 2 2 2 0 rRNA-processing protein Efg1 KH_1 PF00013.29 CBK23420.2 - 8.5e-36 121.6 1.8 2.9e-06 27.0 0.0 7.7 8 0 0 8 8 8 6 KH domain SLS PF14611.6 CBK23420.2 - 1e-10 41.9 0.3 0.0011 18.9 0.0 3.9 3 1 1 4 4 4 2 Mitochondrial inner-membrane-bound regulator Endotoxin_C2 PF18449.1 CBK23420.2 - 0.065 13.6 1.4 2.6 8.4 0.8 3.2 2 1 0 2 2 2 0 Delta endotoxin SspB PF04386.13 CBK23420.2 - 0.075 12.9 0.0 0.33 10.8 0.0 2.0 2 0 0 2 2 2 0 Stringent starvation protein B Prok-E2_B PF14461.6 CBK23420.2 - 0.13 11.9 0.0 0.42 10.3 0.0 1.8 1 0 0 1 1 1 0 Prokaryotic E2 family B EF-hand_7 PF13499.6 CBK23421.2 - 1.7e-08 34.8 1.1 0.00044 20.6 0.6 2.4 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 CBK23421.2 - 8e-06 25.4 0.9 0.009 15.9 0.1 3.1 3 0 0 3 3 3 2 EF-hand domain EF-hand_9 PF14658.6 CBK23421.2 - 6.6e-05 23.2 0.0 0.19 12.1 0.0 2.4 2 1 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.32 CBK23421.2 - 0.0012 18.2 0.7 0.74 9.5 0.1 3.6 3 0 0 3 3 3 1 EF hand EF-hand_8 PF13833.6 CBK23421.2 - 0.05 13.4 2.8 1.1 9.2 0.5 3.3 2 2 2 4 4 4 0 EF-hand domain pair SR-25 PF10500.9 CBK23422.2 - 0.24 11.0 9.6 0.32 10.6 9.6 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF755 PF05501.11 CBK23422.2 - 0.96 9.7 12.8 1.6 9.1 12.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF755) ArfGap PF01412.18 CBK23423.2 - 2.4e-18 66.3 1.4 5.9e-18 65.1 1.4 1.7 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf CDC45 PF02724.14 CBK23423.2 - 0.31 9.3 5.7 0.37 9.0 5.7 1.2 1 0 0 1 1 1 0 CDC45-like protein SRP-alpha_N PF04086.13 CBK23423.2 - 1.8 8.4 13.4 2.8 7.8 13.4 1.4 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal TB2_DP1_HVA22 PF03134.19 CBK23424.2 - 0.0012 18.7 2.5 0.0012 18.7 2.5 2.0 1 1 1 2 2 2 1 TB2/DP1, HVA22 family DUF3522 PF12036.8 CBK23424.2 - 0.023 15.0 6.6 0.03 14.6 6.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3522) Spore_YhaL PF14147.6 CBK23424.2 - 0.098 12.4 1.4 0.21 11.3 0.1 2.1 2 0 0 2 2 2 0 Sporulation protein YhaL Col_cuticle_N PF01484.17 CBK23424.2 - 0.13 12.4 1.8 0.23 11.6 0.0 2.2 2 0 0 2 2 2 0 Nematode cuticle collagen N-terminal domain CPBP PF02517.16 CBK23424.2 - 3.2 8.2 7.4 6.9 7.1 0.9 2.2 1 1 1 2 2 2 0 CPBP intramembrane metalloprotease UAA PF08449.11 CBK23425.2 - 1.5e-38 132.8 9.5 1.7e-38 132.6 9.5 1.0 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.20 CBK23425.2 - 2.3e-06 27.8 7.7 8.6e-06 26.0 1.8 2.1 2 0 0 2 2 2 2 EamA-like transporter family CRT-like PF08627.10 CBK23425.2 - 0.0011 18.0 2.4 0.0011 18.0 2.4 1.4 1 1 0 1 1 1 1 CRT-like, chloroquine-resistance transporter-like Nuc_sug_transp PF04142.15 CBK23425.2 - 0.017 14.3 3.4 0.02 14.0 3.4 1.1 1 0 0 1 1 1 0 Nucleotide-sugar transporter Acyltransferase PF01553.21 CBK23426.2 - 3.6e-06 26.6 0.0 1.3e-05 24.8 0.0 1.8 1 1 0 1 1 1 1 Acyltransferase DUF1616 PF07760.11 CBK23426.2 - 0.11 11.8 0.1 0.17 11.3 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1616) G-patch PF01585.23 CBK23427.2 - 2.6e-14 52.8 1.8 4e-14 52.2 1.8 1.3 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 CBK23427.2 - 1.4e-06 28.3 2.4 2.6e-06 27.4 2.4 1.4 1 0 0 1 1 1 1 G-patch domain Sarcoglycan_2 PF05510.13 CBK23427.2 - 0.018 13.9 0.3 0.022 13.6 0.3 1.1 1 0 0 1 1 1 0 Sarcoglycan alpha/epsilon RhoGEF PF00621.20 CBK23428.2 - 8.7e-22 78.2 0.7 1.4e-21 77.6 0.7 1.3 1 0 0 1 1 1 1 RhoGEF domain Ribosomal_L37ae PF01780.19 CBK23429.2 - 7.6e-28 96.4 4.8 8.3e-28 96.3 4.8 1.0 1 0 0 1 1 1 1 Ribosomal L37ae protein family zf-BED PF02892.15 CBK23429.2 - 0.0075 16.3 5.6 0.34 11.0 0.9 2.2 1 1 1 2 2 2 2 BED zinc finger zf_UBZ PF18439.1 CBK23429.2 - 0.039 13.6 1.1 7.3 6.3 0.2 2.3 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger DUF1451 PF07295.11 CBK23429.2 - 0.062 13.3 3.0 0.077 13.0 3.0 1.1 1 0 0 1 1 1 0 Zinc-ribbon containing domain zf-RING_13 PF17977.1 CBK23429.2 - 0.064 13.4 3.7 0.075 13.2 3.7 1.1 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Zn_Tnp_IS1595 PF12760.7 CBK23429.2 - 0.22 11.5 7.7 0.92 9.5 8.0 1.8 1 1 1 2 2 2 0 Transposase zinc-ribbon domain Rep_fac-A_C PF08646.10 CBK23429.2 - 1.1 9.0 4.8 4.9 6.9 4.8 1.9 1 1 0 1 1 1 0 Replication factor-A C terminal domain zf-H2C2_2 PF13465.6 CBK23429.2 - 1.9 9.0 9.0 2.7 8.6 0.7 2.2 1 1 1 2 2 2 0 Zinc-finger double domain UCH PF00443.29 CBK23430.2 - 1.3e-24 87.1 0.0 2.7e-24 86.1 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 CBK23430.2 - 2.1e-11 43.9 2.2 4.1e-11 43.0 2.2 1.5 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein IPK PF03770.16 CBK23431.2 - 4.8e-35 121.2 0.0 1.8e-34 119.3 0.0 1.8 1 1 0 1 1 1 1 Inositol polyphosphate kinase TIP49 PF06068.13 CBK23432.2 - 3.3e-163 542.9 0.3 4.1e-163 542.6 0.3 1.1 1 0 0 1 1 1 1 TIP49 P-loop domain TIP49_C PF17856.1 CBK23432.2 - 1.9e-15 56.7 0.9 7.6e-15 54.8 0.9 2.0 1 0 0 1 1 1 1 TIP49 AAA-lid domain AAA PF00004.29 CBK23432.2 - 1.2e-11 45.2 0.1 3.1e-07 30.9 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 CBK23432.2 - 2e-08 34.1 0.7 2.9e-05 23.9 0.0 2.5 2 1 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 CBK23432.2 - 3e-07 30.8 0.1 0.024 14.9 0.1 2.6 1 1 1 2 2 2 2 AAA domain AAA_5 PF07728.14 CBK23432.2 - 3.8e-05 23.7 0.0 0.0094 16.0 0.0 2.7 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 CBK23432.2 - 5.2e-05 23.7 0.1 0.00063 20.2 0.1 2.2 1 1 0 1 1 1 1 AAA ATPase domain Mg_chelatase PF01078.21 CBK23432.2 - 0.0002 20.8 0.3 0.0048 16.3 0.1 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_19 PF13245.6 CBK23432.2 - 0.00097 19.5 0.3 0.93 9.8 0.1 2.5 2 0 0 2 2 2 2 AAA domain Sigma54_activat PF00158.26 CBK23432.2 - 0.002 17.8 0.0 1.1 8.9 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain IstB_IS21 PF01695.17 CBK23432.2 - 0.0024 17.6 0.3 0.0066 16.2 0.1 1.8 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_28 PF13521.6 CBK23432.2 - 0.0064 16.7 0.1 0.017 15.4 0.0 1.7 2 0 0 2 2 1 1 AAA domain AAA_25 PF13481.6 CBK23432.2 - 0.0065 16.1 0.2 0.018 14.6 0.1 1.6 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 CBK23432.2 - 0.018 15.6 0.0 0.14 12.7 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_11 PF13086.6 CBK23432.2 - 0.028 14.2 0.1 0.071 12.9 0.0 1.6 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 CBK23432.2 - 0.044 13.5 0.2 2.6 7.7 0.0 2.4 2 1 0 2 2 2 0 AAA domain AAA_7 PF12775.7 CBK23432.2 - 0.048 13.2 0.1 0.2 11.1 0.0 2.0 2 0 0 2 2 2 0 P-loop containing dynein motor region DnaB_C PF03796.15 CBK23432.2 - 0.051 12.9 0.0 0.2 11.0 0.0 1.9 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain AAA_17 PF13207.6 CBK23432.2 - 0.054 13.9 0.1 1.2 9.6 0.0 2.7 2 1 0 2 2 2 0 AAA domain ResIII PF04851.15 CBK23432.2 - 0.066 13.2 0.1 3.2 7.7 0.0 2.4 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit Rad17 PF03215.15 CBK23432.2 - 0.069 13.1 0.0 0.15 12.0 0.0 1.5 1 0 0 1 1 1 0 Rad17 P-loop domain PIF1 PF05970.14 CBK23432.2 - 0.08 12.1 0.0 4.2 6.4 0.0 2.2 2 0 0 2 2 2 0 PIF1-like helicase Sigma54_activ_2 PF14532.6 CBK23432.2 - 0.1 12.7 0.0 3.9 7.6 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain ABC_tran PF00005.27 CBK23432.2 - 0.12 12.9 0.0 0.29 11.7 0.0 1.7 1 1 0 1 1 1 0 ABC transporter RRS1 PF04939.12 CBK23433.2 - 8e-37 126.6 1.9 1e-36 126.3 1.9 1.0 1 0 0 1 1 1 1 Ribosome biogenesis regulatory protein (RRS1) U1snRNP70_N PF12220.8 CBK23433.2 - 0.026 15.1 0.6 0.031 14.9 0.6 1.1 1 0 0 1 1 1 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal TMEM51 PF15345.6 CBK23434.2 - 0.087 12.7 0.0 0.087 12.7 0.0 1.1 1 0 0 1 1 1 0 Transmembrane protein 51 Nrap_D3 PF17404.2 CBK23435.2 - 5.8e-26 91.5 0.0 9.7e-26 90.8 0.0 1.3 1 0 0 1 1 1 1 Nrap protein domain 3 Nrap_D5 PF17406.2 CBK23435.2 - 3.7e-18 65.8 0.1 2.2e-17 63.3 0.1 2.3 3 0 0 3 3 3 1 Nrap protein PAP/OAS1-like domain 5 Nrap_D4 PF17405.2 CBK23435.2 - 3.9e-09 36.2 0.0 6.2e-09 35.5 0.0 1.2 1 0 0 1 1 1 1 Nrap protein nucleotidyltransferase domain 4 Nrap_D6 PF17407.2 CBK23435.2 - 3.5e-06 27.3 0.0 9.8e-06 25.8 0.0 1.8 1 0 0 1 1 1 1 Nrap protein domain 6 CTC1 PF15489.6 CBK23435.2 - 0.064 10.8 0.1 0.087 10.3 0.1 1.1 1 0 0 1 1 1 0 CST, telomere maintenance, complex subunit CTC1 zf-TAZ PF02135.16 CBK23437.2 - 4.4e-09 36.7 10.9 1e-08 35.5 10.9 1.6 1 0 0 1 1 1 1 TAZ zinc finger zf-CW PF07496.15 CBK23437.2 - 7.5e-08 32.3 0.9 2.3e-07 30.7 0.9 1.9 1 0 0 1 1 1 1 CW-type Zinc Finger ARID PF01388.21 CBK23437.2 - 0.00035 21.2 0.0 0.00082 20.0 0.0 1.5 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain MFS_1 PF07690.16 CBK23438.2 - 1.4e-29 103.2 27.8 5.6e-29 101.2 21.6 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily OSTbeta PF15048.6 CBK23438.2 - 0.022 14.9 0.8 0.24 11.6 0.1 2.5 2 0 0 2 2 2 0 Organic solute transporter subunit beta protein Peptidase_S49_N PF08496.10 CBK23438.2 - 0.054 13.6 3.4 0.32 11.0 0.0 3.0 3 0 0 3 3 3 0 Peptidase family S49 N-terminal FAM176 PF14851.6 CBK23438.2 - 0.13 11.9 0.1 2.8 7.6 0.0 2.2 2 0 0 2 2 2 0 FAM176 family OATP PF03137.20 CBK23438.2 - 8.1 4.6 13.3 0.73 8.0 0.2 3.3 2 1 0 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family Pkinase PF00069.25 CBK23439.2 - 2.1e-65 220.7 0.0 3.4e-65 220.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain SecY PF00344.20 CBK23439.2 - 3.3e-65 220.4 9.8 4.5e-65 219.9 9.8 1.2 1 0 0 1 1 1 1 SecY translocase Pkinase_Tyr PF07714.17 CBK23439.2 - 4.2e-28 98.3 0.0 6.7e-28 97.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Plug_translocon PF10559.9 CBK23439.2 - 3e-17 62.1 0.1 8.6e-17 60.7 0.1 1.9 1 0 0 1 1 1 1 Plug domain of Sec61p Pkinase_fungal PF17667.1 CBK23439.2 - 9.2e-07 28.0 0.0 1.3e-06 27.5 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase EF-hand_6 PF13405.6 CBK23439.2 - 0.0092 15.8 0.4 0.027 14.4 0.4 1.8 1 0 0 1 1 1 1 EF-hand domain Haspin_kinase PF12330.8 CBK23439.2 - 0.084 11.8 0.1 0.14 11.1 0.1 1.3 1 0 0 1 1 1 0 Haspin like kinase domain APH PF01636.23 CBK23439.2 - 0.12 12.3 0.0 0.25 11.2 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family EcKinase PF02958.20 CBK23439.2 - 0.13 11.5 0.0 0.25 10.6 0.0 1.4 1 0 0 1 1 1 0 Ecdysteroid kinase PCI PF01399.27 CBK23440.2 - 9.4e-14 51.8 3.4 1e-13 51.7 0.1 2.6 3 0 0 3 3 3 1 PCI domain Rrf2 PF02082.20 CBK23440.2 - 0.0097 16.2 0.0 0.033 14.5 0.0 1.9 1 0 0 1 1 1 1 Transcriptional regulator MarR_2 PF12802.7 CBK23440.2 - 0.029 14.3 0.0 0.06 13.3 0.0 1.5 1 0 0 1 1 1 0 MarR family Sigma70_r4_2 PF08281.12 CBK23440.2 - 0.03 14.0 0.0 0.069 12.8 0.0 1.6 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_23 PF13384.6 CBK23440.2 - 0.13 12.1 0.0 0.26 11.1 0.0 1.5 1 0 0 1 1 1 0 Homeodomain-like domain HTH_Tnp_ISL3 PF13542.6 CBK23440.2 - 0.13 11.7 0.0 0.28 10.7 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 DUF4611 PF15387.6 CBK23441.2 - 2.2 8.6 6.6 1.5 9.1 2.8 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4611) MFS_1 PF07690.16 CBK23442.2 - 5.5e-07 28.8 3.0 6.6e-07 28.6 3.0 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily PTR2 PF00854.21 CBK23442.2 - 0.00033 19.6 0.8 0.00033 19.6 0.8 1.3 2 0 0 2 2 2 1 POT family SHR3_chaperone PF08229.11 CBK23442.2 - 0.0012 17.9 0.1 0.0012 17.9 0.1 1.6 2 0 0 2 2 2 1 ER membrane protein SH3 PIG-Y PF15159.6 CBK23442.2 - 2.3 9.2 7.3 7.9 7.5 7.3 2.1 1 1 0 1 1 1 0 Phosphatidylinositol N-acetylglucosaminyltransferase subunit Y UPF0547 PF10571.9 CBK23444.2 - 6.4 6.9 10.7 0.61 10.2 0.2 3.2 3 0 0 3 3 3 0 Uncharacterised protein family UPF0547 Kinesin PF00225.23 CBK23445.2 - 1.1e-11 44.2 0.2 1.4e-11 44.0 0.2 1.0 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 CBK23445.2 - 0.0026 17.7 0.2 0.0053 16.7 0.1 1.6 1 1 1 2 2 2 1 Microtubule binding TAFH PF07531.14 CBK23445.2 - 0.033 14.3 0.1 0.36 10.9 0.1 2.2 1 1 0 1 1 1 0 NHR1 homology to TAF RPA43_OB PF17875.1 CBK23446.2 - 0.0085 16.7 0.0 0.05 14.2 0.0 1.8 1 1 1 2 2 2 1 RPA43 OB domain in RNA Pol I RNA_pol_Rbc25 PF08292.12 CBK23446.2 - 0.032 14.4 0.0 0.039 14.2 0.0 1.1 1 0 0 1 1 1 0 RNA polymerase III subunit Rpc25 WD40 PF00400.32 CBK23447.2 - 6.8e-26 90.0 0.6 4.1e-05 24.3 0.0 5.9 6 0 0 6 6 6 5 WD domain, G-beta repeat CAF1C_H4-bd PF12265.8 CBK23447.2 - 1.3e-24 86.2 0.6 4.7e-24 84.4 0.7 2.0 2 0 0 2 2 2 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex ANAPC4_WD40 PF12894.7 CBK23447.2 - 6e-09 36.1 0.1 0.0061 16.8 0.0 4.1 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 CBK23448.2 - 0.0046 17.8 0.2 0.044 14.7 0.0 2.6 3 0 0 3 3 3 1 WD domain, G-beta repeat RAP1 PF07218.11 CBK23448.2 - 9.7 4.3 9.7 13 3.9 9.7 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) PHO4 PF01384.20 CBK23449.2 - 1.5e-109 366.2 19.6 1.8e-109 365.9 19.6 1.1 1 0 0 1 1 1 1 Phosphate transporter family Peptidase_M20 PF01546.28 CBK23450.2 - 4.7e-14 52.6 0.0 9.2e-14 51.6 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 CBK23450.2 - 2.7e-07 30.5 0.0 7.2e-07 29.1 0.0 1.7 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 CBK23450.2 - 0.056 13.1 0.0 0.098 12.3 0.0 1.4 1 0 0 1 1 1 0 Peptidase family M28 ATP-synt_ab PF00006.25 CBK23451.2 - 1.2e-65 221.1 0.0 1.7e-65 220.7 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 CBK23451.2 - 6.3e-10 39.4 0.4 1.1e-09 38.6 0.4 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain HAS-barrel PF09378.10 CBK23451.2 - 0.028 14.6 0.1 0.066 13.4 0.1 1.7 1 0 0 1 1 1 0 HAS barrel domain 14-3-3 PF00244.20 CBK23452.2 - 1e-66 224.6 5.6 1.2e-66 224.4 5.6 1.0 1 0 0 1 1 1 1 14-3-3 protein ATPase_2 PF01637.18 CBK23452.2 - 0.052 13.5 0.6 0.094 12.6 0.6 1.6 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea TIP49 PF06068.13 CBK23454.2 - 1.1e-120 403.1 0.9 1.5e-120 402.7 0.9 1.1 1 0 0 1 1 1 1 TIP49 P-loop domain TIP49_C PF17856.1 CBK23454.2 - 6.4e-23 80.7 0.2 1.7e-22 79.3 0.2 1.8 1 0 0 1 1 1 1 TIP49 AAA-lid domain Sipho_tail PF05709.11 CBK23454.2 - 0.035 13.5 0.1 0.064 12.7 0.1 1.5 1 0 0 1 1 1 0 Phage tail protein AAA_22 PF13401.6 CBK23454.2 - 0.074 13.3 0.0 0.17 12.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain CENP-X PF09415.10 CBK23455.2 - 5.2e-13 49.1 0.2 5.8e-13 49.0 0.2 1.0 1 0 0 1 1 1 1 CENP-S associating Centromere protein X Pkinase PF00069.25 CBK23457.2 - 5.7e-13 48.8 0.0 9.2e-13 48.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBK23457.2 - 2e-05 24.0 0.0 0.00011 21.6 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase DIM1 PF02966.16 CBK23457.2 - 0.12 12.2 0.0 15 5.4 0.0 2.7 3 0 0 3 3 3 0 Mitosis protein DIM1 Pkinase PF00069.25 CBK23458.2 - 9.8e-17 61.2 0.0 1.4e-16 60.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBK23458.2 - 0.00017 21.0 0.0 0.00027 20.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase DUF4276 PF14103.6 CBK23458.2 - 0.11 12.7 0.1 12 6.1 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4276) FPRL1_inhibitor PF16104.5 CBK23458.2 - 0.16 12.1 0.1 0.28 11.3 0.1 1.3 1 0 0 1 1 1 0 Formyl peptide receptor-like 1 inhibitory protein Spem1 PF15670.5 CBK23458.2 - 1.2 8.7 9.9 2.3 7.7 9.9 1.4 1 0 0 1 1 1 0 Spermatid maturation protein 1 RabGAP-TBC PF00566.18 CBK23459.2 - 5e-52 176.7 0.4 7e-52 176.2 0.4 1.1 1 0 0 1 1 1 1 Rab-GTPase-TBC domain tRNA-synt_1e PF01406.19 CBK23459.2 - 0.13 11.5 0.1 0.3 10.4 0.0 1.5 1 1 0 1 1 1 0 tRNA synthetases class I (C) catalytic domain ETC_C1_NDUFA5 PF04716.14 CBK23460.2 - 2.1e-24 85.1 0.2 3e-24 84.6 0.2 1.2 1 0 0 1 1 1 1 ETC complex I subunit conserved region Pkinase PF00069.25 CBK23461.2 - 3.7e-55 187.1 0.0 4.7e-55 186.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBK23461.2 - 1.4e-16 60.5 0.0 4.6e-16 58.9 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 CBK23461.2 - 7.2e-07 29.4 0.0 3.2e-06 27.3 0.0 1.7 1 1 0 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 CBK23461.2 - 0.0064 16.1 0.0 0.013 15.0 0.0 1.5 1 0 0 1 1 1 1 Choline/ethanolamine kinase Haspin_kinase PF12330.8 CBK23461.2 - 0.064 12.2 0.0 0.35 9.7 0.0 1.8 2 0 0 2 2 2 0 Haspin like kinase domain Kinase-like PF14531.6 CBK23461.2 - 0.12 11.6 0.0 10 5.3 0.0 2.3 2 0 0 2 2 2 0 Kinase-like Trm112p PF03966.16 CBK23462.2 - 6.2e-13 49.1 0.0 7.7e-13 48.8 0.0 1.1 1 0 0 1 1 1 1 Trm112p-like protein zf-BED PF02892.15 CBK23462.2 - 0.02 14.9 0.0 0.037 14.0 0.0 1.4 1 0 0 1 1 1 0 BED zinc finger Zn_ribbon_recom PF13408.6 CBK23462.2 - 0.083 13.4 0.2 0.14 12.7 0.2 1.3 1 0 0 1 1 1 0 Recombinase zinc beta ribbon domain MRP-L46 PF11788.8 CBK23463.2 - 0.021 15.6 0.1 0.021 15.6 0.1 2.5 3 0 0 3 3 3 0 39S mitochondrial ribosomal protein L46 5-FTHF_cyc-lig PF01812.20 CBK23464.2 - 1.7e-31 109.5 0.0 1.9e-31 109.4 0.0 1.0 1 0 0 1 1 1 1 5-formyltetrahydrofolate cyclo-ligase family GTP_EFTU PF00009.27 CBK23465.2 - 1.1e-44 152.4 0.0 1.4e-44 152.0 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 CBK23465.2 - 7.7e-30 103.5 1.1 2.9e-29 101.6 0.3 2.3 3 0 0 3 3 3 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 CBK23465.2 - 1.6e-07 31.6 0.2 4.2e-07 30.3 0.2 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 CBK23465.2 - 0.0013 18.8 0.1 0.0094 16.0 0.1 2.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase Dioxygenase_N PF04444.14 CBK23465.2 - 0.094 12.6 0.2 1.5 8.7 0.0 2.4 2 0 0 2 2 2 0 Catechol dioxygenase N terminus GTP_EFTU_D4 PF14578.6 CBK23465.2 - 0.12 12.3 0.1 0.33 10.9 0.1 1.7 1 0 0 1 1 1 0 Elongation factor Tu domain 4 FeoB_N PF02421.18 CBK23465.2 - 0.14 11.7 0.1 4.1 6.9 0.0 2.8 3 0 0 3 3 3 0 Ferrous iron transport protein B AAA_29 PF13555.6 CBK23465.2 - 0.15 11.9 0.0 4.4 7.1 0.0 2.4 2 0 0 2 2 2 0 P-loop containing region of AAA domain PRCC PF10253.9 CBK23465.2 - 0.21 12.4 2.5 0.36 11.6 2.5 1.4 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting CDC27 PF09507.10 CBK23465.2 - 6.2 6.1 7.2 11 5.2 7.2 1.4 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 DEC-1_N PF04625.13 CBK23465.2 - 9.9 5.1 16.7 15 4.4 16.7 1.2 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region zf-RING_2 PF13639.6 CBK23466.2 - 2.7e-13 50.0 5.9 5.5e-13 49.0 5.9 1.6 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 CBK23466.2 - 1.2e-10 41.4 3.8 2.8e-10 40.3 3.8 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_11 PF17123.5 CBK23466.2 - 4.9e-10 39.0 2.7 1.1e-09 37.8 2.7 1.7 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4 PF00097.25 CBK23466.2 - 7.5e-08 32.1 5.7 1.7e-07 31.0 5.7 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CBK23466.2 - 8.3e-08 32.1 1.4 1.4e-07 31.5 0.6 1.8 1 1 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 CBK23466.2 - 1.1e-07 31.6 5.4 2.3e-07 30.5 5.4 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CBK23466.2 - 1.5e-07 31.3 4.2 2.9e-07 30.3 4.2 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 CBK23466.2 - 6e-07 29.2 3.1 1.1e-06 28.4 3.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 CBK23466.2 - 1.9e-05 24.4 5.9 4.1e-05 23.3 5.9 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 Prok-RING_1 PF14446.6 CBK23466.2 - 0.00026 20.9 4.0 0.0014 18.5 2.9 2.3 1 1 1 2 2 2 1 Prokaryotic RING finger family 1 zf-ANAPC11 PF12861.7 CBK23466.2 - 0.0012 18.9 2.9 0.0031 17.5 2.9 1.6 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_ribbon_17 PF17120.5 CBK23466.2 - 0.0094 15.6 3.7 0.02 14.5 3.7 1.5 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type Baculo_PEP_C PF04513.12 CBK23466.2 - 0.02 14.9 2.0 0.56 10.3 0.2 2.4 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus zf-C3HC4_4 PF15227.6 CBK23466.2 - 0.023 14.8 6.2 0.031 14.4 4.6 2.1 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.6 CBK23466.2 - 0.16 11.8 3.0 0.33 10.8 3.0 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Baculo_RING PF05883.11 CBK23466.2 - 0.2 11.7 1.2 0.65 10.0 0.0 2.2 2 0 0 2 2 2 0 Baculovirus U-box/Ring-like domain TFIIA_gamma_N PF02268.16 CBK23466.2 - 0.43 10.6 2.3 0.83 9.7 0.3 2.3 2 1 0 2 2 2 0 Transcription initiation factor IIA, gamma subunit, helical domain LMBR1 PF04791.16 CBK23466.2 - 0.48 9.3 2.7 0.67 8.8 2.7 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein CdvA PF18822.1 CBK23466.2 - 0.78 9.6 10.9 4 7.3 0.7 2.8 2 1 1 3 3 3 0 CdvA-like coiled-coil domain RINGv PF12906.7 CBK23466.2 - 3.1 8.0 7.7 3.2 7.9 5.5 2.1 1 1 1 2 2 2 0 RING-variant domain PHD PF00628.29 CBK23466.2 - 4.6 7.2 7.2 2.3 8.2 4.5 1.9 2 0 0 2 2 2 0 PHD-finger Phage_Mu_Gam PF07352.12 CBK23466.2 - 5.9 6.8 10.3 5.9 6.8 0.7 2.6 2 1 1 3 3 3 0 Bacteriophage Mu Gam like protein DUF4407 PF14362.6 CBK23466.2 - 10 5.4 11.0 2e+02 1.2 11.0 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) TauE PF01925.19 CBK23467.2 - 9.4e-46 156.4 13.1 1.2e-23 84.1 0.9 2.0 2 0 0 2 2 2 2 Sulfite exporter TauE/SafE UPF0016 PF01169.19 CBK23467.2 - 0.0069 16.7 1.0 0.0069 16.7 1.0 3.5 2 2 1 3 3 3 1 Uncharacterized protein family UPF0016 Lung_7-TM_R PF06814.13 CBK23468.2 - 2.4e-48 164.9 27.5 2.9e-48 164.6 27.5 1.1 1 0 0 1 1 1 1 Lung seven transmembrane receptor GpcrRhopsn4 PF10192.9 CBK23468.2 - 0.00069 19.1 27.3 0.0018 17.7 25.0 2.2 1 1 1 2 2 2 1 Rhodopsin-like GPCR transmembrane domain VCBS PF13517.6 CBK23469.2 - 0.005 17.4 6.4 0.028 15.0 0.9 2.8 3 0 0 3 3 3 1 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella PQQ_2 PF13360.6 CBK23469.2 - 0.047 13.3 0.0 0.44 10.1 0.0 2.1 1 1 0 1 1 1 0 PQQ-like domain Filamin PF00630.19 CBK23469.2 - 0.052 14.4 0.0 0.095 13.5 0.0 1.5 1 1 0 1 1 1 0 Filamin/ABP280 repeat FG-GAP PF01839.23 CBK23469.2 - 4.5 7.5 7.3 0.45 10.7 2.1 2.0 2 0 0 2 2 2 0 FG-GAP repeat Clathrin PF00637.20 CBK23470.2 - 1.1e-14 54.5 12.3 8.1e-14 51.7 6.3 2.9 3 1 0 3 3 3 1 Region in Clathrin and VPS Pep3_Vps18 PF05131.14 CBK23470.2 - 1.3e-12 47.8 0.0 2.8e-12 46.7 0.0 1.5 1 0 0 1 1 1 1 Pep3/Vps18/deep orange family Vps39_2 PF10367.9 CBK23470.2 - 3.2e-07 30.8 0.0 1.2e-06 28.9 0.0 2.1 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 2 zf-C3HC4_2 PF13923.6 CBK23470.2 - 0.00072 19.3 1.8 0.00072 19.3 1.8 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 CBK23470.2 - 0.0029 17.2 0.6 0.0029 17.2 0.6 1.7 2 0 0 2 2 1 1 Zinc-ribbon, C4HC2 type zf-RING_5 PF14634.6 CBK23470.2 - 0.0036 17.2 2.2 0.0094 15.9 0.7 2.3 2 0 0 2 2 2 1 zinc-RING finger domain Apolipoprotein PF01442.18 CBK23470.2 - 0.0049 16.8 4.4 0.045 13.6 1.7 2.6 2 0 0 2 2 2 1 Apolipoprotein A1/A4/E domain zf-RING_2 PF13639.6 CBK23470.2 - 0.011 16.1 1.6 0.011 16.1 1.6 2.3 2 0 0 2 2 2 0 Ring finger domain zf-RING_11 PF17123.5 CBK23470.2 - 0.012 15.4 3.4 0.012 15.4 3.4 2.2 2 0 0 2 2 2 0 RING-like zinc finger zf-RING_UBOX PF13445.6 CBK23470.2 - 0.024 14.7 0.5 0.075 13.1 0.5 1.9 1 0 0 1 1 1 0 RING-type zinc-finger Dynactin_p22 PF07426.11 CBK23470.2 - 0.028 14.3 1.5 0.06 13.2 1.5 1.5 1 0 0 1 1 1 0 Dynactin subunit p22 Zf_RING PF16744.5 CBK23470.2 - 0.03 14.4 2.6 0.057 13.5 0.4 2.3 2 0 0 2 2 2 0 KIAA1045 RING finger DUF2175 PF09943.9 CBK23470.2 - 0.064 13.5 0.1 0.22 11.8 0.1 2.0 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2175) Spore_Cse60 PF10957.8 CBK23470.2 - 0.11 12.5 1.5 0.24 11.4 1.5 1.5 1 0 0 1 1 1 0 Sporulation protein Cse60 7TMR-HDED PF07697.11 CBK23470.2 - 0.14 12.3 0.1 0.36 10.9 0.1 1.6 1 0 0 1 1 1 0 7TM-HD extracellular Taxilin PF09728.9 CBK23470.2 - 0.14 11.3 1.5 0.27 10.4 0.0 1.9 2 0 0 2 2 2 0 Myosin-like coiled-coil protein CorA PF01544.18 CBK23470.2 - 0.31 10.3 1.0 0.59 9.4 1.0 1.4 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein zf-rbx1 PF12678.7 CBK23470.2 - 0.5 10.7 3.6 0.34 11.2 0.6 2.2 2 0 0 2 2 2 0 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 CBK23470.2 - 0.79 9.6 4.1 0.51 10.2 1.0 2.2 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) bZIP_1 PF00170.21 CBK23470.2 - 2.3 8.4 5.2 0.48 10.5 0.3 2.4 2 0 0 2 2 2 0 bZIP transcription factor ZapB PF06005.12 CBK23470.2 - 6.1 7.4 8.0 1.7 9.1 0.2 2.5 2 0 0 2 2 2 0 Cell division protein ZapB Aa_trans PF01490.18 CBK23471.2 - 1.2e-14 53.9 21.6 1.4e-14 53.6 21.6 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DUF2039 PF10217.9 CBK23472.2 - 2.9e-29 101.3 15.4 2.9e-29 101.3 15.4 1.9 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2039) Cript PF10235.9 CBK23472.2 - 0.012 16.2 9.8 0.012 16.2 9.8 2.6 1 1 2 3 3 3 0 Microtubule-associated protein CRIPT DUF2757 PF10955.8 CBK23472.2 - 0.13 12.5 0.0 0.13 12.5 0.0 3.2 3 1 1 4 4 4 0 Protein of unknown function (DUF2757) HypA PF01155.19 CBK23472.2 - 6.7 6.8 17.5 0.04 13.9 3.7 2.3 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Ist1 PF03398.14 CBK23473.2 - 5.7e-12 45.9 4.7 1.1e-11 44.9 4.7 1.4 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway ASD2 PF08687.11 CBK23473.2 - 0.0046 16.5 1.2 0.0046 16.5 1.2 3.1 2 1 1 3 3 3 1 Apx/Shroom domain ASD2 Hexapep PF00132.24 CBK23474.2 - 6e-12 44.8 13.0 1e-05 25.1 0.1 4.1 3 1 1 4 4 4 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 CBK23474.2 - 7.9e-06 25.5 12.6 8.4e-05 22.2 0.3 2.9 4 0 0 4 4 4 2 Hexapeptide repeat of succinyl-transferase Fucokinase PF07959.12 CBK23474.2 - 0.00027 20.0 1.3 0.025 13.5 0.2 2.1 1 1 1 2 2 2 2 L-fucokinase DUF4954 PF16314.5 CBK23474.2 - 0.13 10.4 0.7 0.15 10.1 0.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4954) BILBO1_N PF18281.1 CBK23475.2 - 0.027 14.9 0.1 6.7 7.2 0.0 2.1 2 0 0 2 2 2 0 BILBO1 N-terminal domain UPF0730 PF15827.5 CBK23475.2 - 0.12 12.1 0.3 0.22 11.3 0.3 1.4 1 0 0 1 1 1 0 UPF0730 unknown protein family ATP_bind_1 PF03029.17 CBK23476.2 - 0.011 15.5 0.1 0.014 15.2 0.1 1.1 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein ADK PF00406.22 CBK23477.2 - 5e-36 124.1 0.0 6.2e-36 123.8 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 CBK23477.2 - 1.9e-30 106.0 1.5 4.6e-30 104.8 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 CBK23477.2 - 2.5e-11 44.3 0.0 2.5e-11 44.3 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 CBK23477.2 - 1e-06 28.9 0.0 3e-06 27.5 0.0 1.7 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 CBK23477.2 - 1.1e-06 28.1 0.0 1.4e-05 24.5 0.0 2.1 1 1 0 1 1 1 1 Zeta toxin CPT PF07931.12 CBK23477.2 - 0.0031 17.4 0.0 0.007 16.2 0.0 1.6 1 1 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein AAA_PrkA PF08298.11 CBK23477.2 - 0.035 13.0 0.0 0.08 11.8 0.0 1.5 2 0 0 2 2 2 0 PrkA AAA domain Ploopntkinase3 PF18751.1 CBK23477.2 - 0.048 13.6 0.0 0.069 13.0 0.0 1.3 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 CoaE PF01121.20 CBK23477.2 - 0.05 13.3 0.0 0.076 12.7 0.0 1.3 1 0 0 1 1 1 0 Dephospho-CoA kinase DUF4366 PF14283.6 CBK23477.2 - 0.063 13.3 0.5 0.096 12.7 0.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) AAA_19 PF13245.6 CBK23477.2 - 0.065 13.6 0.0 0.12 12.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain LSM PF01423.22 CBK23478.2 - 3.1e-19 68.4 2.4 4.1e-19 68.0 2.4 1.2 1 0 0 1 1 1 1 LSM domain Sec1 PF00995.23 CBK23479.2 - 2.9e-52 178.7 3.0 4.3e-52 178.1 3.0 1.2 1 0 0 1 1 1 1 Sec1 family PH PF00169.29 CBK23479.2 - 0.0013 19.2 0.1 0.003 18.1 0.1 1.7 1 0 0 1 1 1 1 PH domain OapA_N PF08525.11 CBK23479.2 - 0.089 12.8 1.0 5.8 7.0 0.4 2.8 2 0 0 2 2 2 0 Opacity-associated protein A N-terminal motif PH_2 PF08458.10 CBK23479.2 - 0.09 13.1 0.0 0.21 12.0 0.0 1.6 1 0 0 1 1 1 0 Plant pleckstrin homology-like region WD40 PF00400.32 CBK23480.2 - 7.3e-17 61.4 35.1 5.4e-06 27.1 0.8 11.0 13 0 0 13 13 13 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBK23480.2 - 5e-13 49.2 2.4 0.32 11.3 0.0 7.6 6 1 0 7 7 7 4 Anaphase-promoting complex subunit 4 WD40 domain DUF1148 PF06618.11 CBK23480.2 - 0.034 14.3 0.1 1.3 9.2 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1148) Acetyltransf_1 PF00583.25 CBK23481.2 - 6.4e-12 45.7 0.0 1.1e-11 45.0 0.0 1.4 1 1 1 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 CBK23481.2 - 9.9e-08 32.0 0.0 1.3e-07 31.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 CBK23481.2 - 1.1e-06 28.9 0.0 1.5e-06 28.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 CBK23481.2 - 6.9e-06 25.9 0.0 1.4e-05 25.0 0.0 1.5 1 1 0 1 1 1 1 FR47-like protein Acetyltransf_3 PF13302.7 CBK23481.2 - 0.001 19.8 0.0 0.0011 19.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_13 PF13880.6 CBK23481.2 - 0.023 14.6 0.1 1.1 9.3 0.0 2.2 2 0 0 2 2 2 0 ESCO1/2 acetyl-transferase MOZ_SAS PF01853.18 CBK23481.2 - 0.058 13.0 0.0 0.083 12.5 0.0 1.4 1 0 0 1 1 1 0 MOZ/SAS family Acetyltransf_4 PF13420.7 CBK23481.2 - 0.098 12.8 0.1 0.19 11.8 0.0 1.4 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain TPR_2 PF07719.17 CBK23482.2 - 8.4e-14 50.5 4.5 2.6e-06 27.1 1.7 3.1 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.28 CBK23482.2 - 1.1e-12 47.2 5.1 4.4e-06 26.3 2.2 3.1 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.6 CBK23482.2 - 5.1e-06 26.3 3.6 0.17 12.1 0.9 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 CBK23482.2 - 1.7e-05 25.0 0.5 0.001 19.3 0.7 2.5 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 CBK23482.2 - 5.8e-05 23.7 0.7 0.021 15.5 0.0 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.6 CBK23482.2 - 7.8e-05 22.8 0.0 9.3e-05 22.5 0.0 1.1 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_17 PF13431.6 CBK23482.2 - 0.00015 21.9 0.6 1.2 9.6 0.0 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 CBK23482.2 - 0.00038 20.1 0.9 0.00038 20.1 0.9 2.1 3 0 0 3 3 3 1 TPR repeat DUF5113 PF17140.4 CBK23482.2 - 0.0046 16.8 0.3 0.0083 16.0 0.2 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF5113) TPR_19 PF14559.6 CBK23482.2 - 0.0098 16.4 0.0 0.4 11.2 0.0 2.1 2 0 0 2 2 2 1 Tetratricopeptide repeat ANAPC3 PF12895.7 CBK23482.2 - 0.011 16.0 1.7 1.4 9.2 0.4 2.3 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 CBK23482.2 - 0.013 16.1 0.5 0.69 10.7 0.1 2.6 3 0 0 3 3 2 0 Tetratricopeptide repeat SNAP PF14938.6 CBK23482.2 - 0.022 14.2 0.3 0.056 12.9 0.2 1.5 1 1 0 1 1 1 0 Soluble NSF attachment protein, SNAP TPR_7 PF13176.6 CBK23482.2 - 0.046 13.8 2.3 0.55 10.4 0.3 3.1 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.6 CBK23482.2 - 0.065 14.1 0.1 9.2 7.4 0.0 2.9 1 1 2 3 3 3 0 Tetratricopeptide repeat MIT PF04212.18 CBK23482.2 - 0.099 12.7 4.0 1.2 9.2 2.6 2.8 2 1 0 2 2 2 0 MIT (microtubule interacting and transport) domain TPR_3 PF07720.12 CBK23482.2 - 0.13 12.3 1.2 0.21 11.6 0.4 1.8 2 0 0 2 2 2 0 Tetratricopeptide repeat Wzy_C_2 PF11846.8 CBK23482.2 - 0.19 11.6 0.0 0.22 11.4 0.0 1.1 1 0 0 1 1 1 0 Virulence factor membrane-bound polymerase, C-terminal TPR_10 PF13374.6 CBK23482.2 - 0.31 11.0 0.2 0.31 11.0 0.2 2.5 3 1 1 4 4 3 0 Tetratricopeptide repeat adh_short PF00106.25 CBK23483.2 - 3.3e-46 157.2 0.0 6.3e-46 156.3 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CBK23483.2 - 5.4e-32 111.2 0.0 8.1e-32 110.6 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DnaJ PF00226.31 CBK23483.2 - 4.8e-14 52.2 0.2 3.6e-12 46.2 0.1 2.9 1 1 1 2 2 2 1 DnaJ domain KR PF08659.10 CBK23483.2 - 1e-10 41.8 0.0 1.8e-10 41.1 0.0 1.3 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 CBK23483.2 - 0.0013 18.2 0.0 0.0025 17.2 0.0 1.4 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Epimerase PF01370.21 CBK23483.2 - 0.013 15.0 0.0 0.069 12.6 0.0 2.0 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family T5orf172 PF10544.9 CBK23483.2 - 0.1 13.1 2.0 0.27 11.8 2.0 1.7 1 0 0 1 1 1 0 T5orf172 domain DUF4446 PF14584.6 CBK23483.2 - 1.2 9.1 4.6 4.2 7.4 4.6 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) CUTL PF16557.5 CBK23484.2 - 0.005 17.0 1.7 0.33 11.2 0.1 2.3 2 0 0 2 2 2 2 CUT1-like DNA-binding domain of SATB SMC_Nse1 PF07574.13 CBK23484.2 - 0.035 14.0 0.1 0.059 13.2 0.1 1.4 1 1 0 1 1 1 0 Nse1 non-SMC component of SMC5-6 complex Ribosomal_L22e PF01776.17 CBK23485.2 - 4.3e-42 142.9 4.6 5.1e-42 142.7 4.6 1.1 1 0 0 1 1 1 1 Ribosomal L22e protein family DUF2660 PF10859.8 CBK23485.2 - 0.029 14.8 0.2 0.046 14.2 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2660) Bcl-2 PF00452.19 CBK23485.2 - 0.06 14.0 0.0 0.076 13.7 0.0 1.2 1 0 0 1 1 1 0 Apoptosis regulator proteins, Bcl-2 family PG_binding_4 PF12229.8 CBK23485.2 - 0.064 13.5 0.1 0.098 12.9 0.1 1.4 1 0 0 1 1 1 0 Putative peptidoglycan binding domain Phage_int_SAM_5 PF13102.6 CBK23485.2 - 0.078 13.3 1.7 1 9.7 1.7 2.1 1 1 0 1 1 1 0 Phage integrase SAM-like domain HAD_2 PF13419.6 CBK23486.2 - 2.3e-14 53.9 0.1 4.1e-14 53.1 0.1 1.4 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 CBK23486.2 - 2.1e-08 34.1 0.0 3.3e-08 33.5 0.0 1.3 1 0 0 1 1 1 1 HAD-hyrolase-like HAD PF12710.7 CBK23486.2 - 0.0013 19.2 0.0 0.0037 17.7 0.0 1.7 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Apyrase PF06079.11 CBK23487.2 - 2.5e-120 401.1 3.2 3.2e-120 400.8 3.2 1.1 1 0 0 1 1 1 1 Apyrase Sulfate_transp PF00916.20 CBK23487.2 - 5.6e-82 275.5 10.0 2.3e-81 273.5 10.0 1.9 1 1 0 1 1 1 1 Sulfate permease family STAS PF01740.21 CBK23487.2 - 4.2e-08 32.8 0.0 8.5e-08 31.8 0.0 1.5 1 0 0 1 1 1 1 STAS domain STAS_2 PF13466.6 CBK23487.2 - 8.9e-05 22.8 0.0 0.00035 20.9 0.0 1.9 2 0 0 2 2 2 1 STAS domain Nuc_sug_transp PF04142.15 CBK23488.2 - 3.5e-05 23.1 0.5 3.9e-05 23.0 0.5 1.1 1 0 0 1 1 1 1 Nucleotide-sugar transporter EamA PF00892.20 CBK23488.2 - 0.0069 16.6 2.2 0.0077 16.4 2.2 1.1 1 0 0 1 1 1 1 EamA-like transporter family LSM PF01423.22 CBK23489.2 - 1.5e-14 53.4 0.5 1.9e-14 53.1 0.5 1.1 1 0 0 1 1 1 1 LSM domain Hfq PF17209.3 CBK23489.2 - 0.0027 17.3 0.1 0.004 16.8 0.1 1.4 1 0 0 1 1 1 1 Hfq protein DUF777 PF05606.11 CBK23489.2 - 0.013 15.2 0.8 0.015 15.0 0.8 1.1 1 0 0 1 1 1 0 Borrelia burgdorferi protein of unknown function (DUF777) CKS PF01111.19 CBK23490.2 - 2.1e-28 98.4 0.4 2.7e-28 98.0 0.4 1.1 1 0 0 1 1 1 1 Cyclin-dependent kinase regulatory subunit PfkB PF00294.24 CBK23491.2 - 1.2e-17 64.1 0.1 1.4e-17 63.9 0.1 1.1 1 0 0 1 1 1 1 pfkB family carbohydrate kinase PfkB PF00294.24 CBK23492.2 - 1.2e-23 83.9 0.1 1.5e-23 83.6 0.1 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase UBA_4 PF14555.6 CBK23492.2 - 0.16 11.8 0.0 0.32 10.9 0.0 1.5 1 0 0 1 1 1 0 UBA-like domain Pkinase PF00069.25 CBK23493.2 - 9.9e-70 234.9 0.0 1.8e-69 234.0 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBK23493.2 - 1e-52 179.0 0.0 1.7e-52 178.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase DUF21 PF01595.20 CBK23493.2 - 1.6e-32 112.6 0.0 3.1e-32 111.7 0.0 1.5 1 0 0 1 1 1 1 Cyclin M transmembrane N-terminal domain Pkinase_fungal PF17667.1 CBK23493.2 - 9.3e-07 28.0 0.1 9.3e-07 28.0 0.1 1.7 2 0 0 2 2 2 1 Fungal protein kinase CBS PF00571.28 CBK23493.2 - 1.5e-06 28.6 1.2 0.006 17.0 0.0 2.8 2 0 0 2 2 2 2 CBS domain Haspin_kinase PF12330.8 CBK23493.2 - 0.026 13.5 0.3 1.1 8.1 0.3 2.4 1 1 0 1 1 1 0 Haspin like kinase domain Kdo PF06293.14 CBK23493.2 - 0.057 12.8 0.1 0.17 11.3 0.0 1.7 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 CBK23493.2 - 0.14 11.8 1.6 0.88 9.1 0.1 2.3 2 0 0 2 2 2 0 RIO1 family DSBA PF01323.20 CBK23495.2 - 0.00037 20.3 0.0 0.0004 20.2 0.0 1.1 1 0 0 1 1 1 1 DSBA-like thioredoxin domain Thioredoxin_3 PF13192.6 CBK23495.2 - 0.13 12.3 0.0 0.17 12.0 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin domain STAR_dimer PF16544.5 CBK23495.2 - 0.16 11.5 0.0 0.26 10.9 0.0 1.3 1 0 0 1 1 1 0 Homodimerisation region of STAR domain protein ThiF PF00899.21 CBK23496.2 - 6e-33 114.2 0.2 7.1e-33 114.0 0.2 1.1 1 0 0 1 1 1 1 ThiF family Vps51 PF08700.11 CBK23497.2 - 1.1e-05 25.4 0.6 5.7e-05 23.1 0.1 2.5 2 0 0 2 2 2 1 Vps51/Vps67 Zw10 PF06248.13 CBK23497.2 - 0.0012 17.5 1.3 0.002 16.8 1.3 1.3 1 0 0 1 1 1 1 Centromere/kinetochore Zw10 Vps54_N PF10475.9 CBK23497.2 - 0.0019 17.5 0.6 0.0036 16.6 0.6 1.4 1 0 0 1 1 1 1 Vacuolar-sorting protein 54, of GARP complex E2F_TDP PF02319.20 CBK23498.2 - 2.9e-16 59.3 0.0 5.9e-16 58.3 0.0 1.5 1 0 0 1 1 1 1 E2F/DP family winged-helix DNA-binding domain E2F_CC-MB PF16421.5 CBK23498.2 - 1.9e-12 47.4 0.1 4.1e-12 46.3 0.0 1.6 2 0 0 2 2 2 1 E2F transcription factor CC-MB domain Prefoldin_2 PF01920.20 CBK23498.2 - 0.015 15.2 0.2 0.026 14.4 0.2 1.3 1 0 0 1 1 1 0 Prefoldin subunit Phage_sheath_1 PF04984.14 CBK23498.2 - 0.046 13.6 0.0 0.086 12.7 0.0 1.4 1 0 0 1 1 1 0 Phage tail sheath protein subtilisin-like domain Pkinase PF00069.25 CBK23499.2 - 2.5e-42 145.0 0.0 3.1e-42 144.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBK23499.2 - 2.1e-22 79.6 0.0 2.6e-22 79.4 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CBK23499.2 - 1.6e-09 37.5 0.0 2.1e-09 37.1 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 CBK23499.2 - 6.5e-05 22.4 0.0 8.3e-05 22.0 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CBK23499.2 - 0.0013 18.7 0.0 0.002 18.1 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 CBK23499.2 - 0.0036 16.3 0.0 0.0047 15.9 0.0 1.1 1 0 0 1 1 1 1 Haspin like kinase domain Seadorna_VP7 PF07387.11 CBK23499.2 - 0.032 13.3 0.0 0.047 12.8 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 SET PF00856.28 CBK23500.2 - 2.6e-21 76.7 2.0 1.2e-20 74.6 2.0 2.0 1 1 0 1 1 1 1 SET domain FYRC PF05965.14 CBK23500.2 - 0.15 12.2 0.0 0.4 10.9 0.0 1.7 1 0 0 1 1 1 0 F/Y rich C-terminus Bromodomain PF00439.25 CBK23501.2 - 6.1e-11 42.2 1.4 9.5e-11 41.6 0.3 1.9 2 0 0 2 2 2 1 Bromodomain PHD PF00628.29 CBK23501.2 - 1e-07 31.7 24.0 4.1e-07 29.8 17.0 3.2 3 1 0 3 3 3 2 PHD-finger PHD_4 PF16866.5 CBK23501.2 - 0.016 15.3 22.7 0.21 11.7 15.0 3.4 2 1 0 2 2 2 0 PHD-finger zf-PHD-like PF15446.6 CBK23501.2 - 4.6 6.8 16.3 1.7 8.2 0.0 3.2 3 1 0 3 3 3 0 PHD/FYVE-zinc-finger like domain DUF389 PF04087.14 CBK23502.2 - 5.7e-43 146.4 5.7 7e-43 146.1 5.7 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF389) PHO4 PF01384.20 CBK23502.2 - 0.002 17.2 2.5 0.0034 16.5 2.5 1.4 1 1 0 1 1 1 1 Phosphate transporter family YjcB PF15940.5 CBK23502.2 - 6.2 7.1 6.9 6.6 7.0 2.3 2.8 2 1 0 2 2 2 0 Family of unknown function Dus PF01207.17 CBK23503.2 - 4.1e-37 127.9 0.0 4.2e-24 85.2 0.0 2.1 2 0 0 2 2 2 2 Dihydrouridine synthase (Dus) WSN PF02206.18 CBK23503.2 - 0.21 11.5 0.0 0.35 10.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function Bromodomain PF00439.25 CBK23504.2 - 6.1e-11 42.2 1.4 9.5e-11 41.6 0.3 1.9 2 0 0 2 2 2 1 Bromodomain PHD PF00628.29 CBK23504.2 - 1e-07 31.7 24.0 4.1e-07 29.8 17.0 3.2 3 1 0 3 3 3 2 PHD-finger PHD_4 PF16866.5 CBK23504.2 - 0.016 15.3 22.7 0.21 11.7 15.0 3.4 2 1 0 2 2 2 0 PHD-finger zf-PHD-like PF15446.6 CBK23504.2 - 4.6 6.8 16.3 1.7 8.2 0.0 3.2 3 1 0 3 3 3 0 PHD/FYVE-zinc-finger like domain SET PF00856.28 CBK23505.2 - 3.6e-21 76.3 1.6 1.4e-20 74.3 1.6 1.9 1 1 0 1 1 1 1 SET domain Collagen PF01391.18 CBK23505.2 - 1.5e-08 34.3 12.2 3.9e-08 32.9 12.2 1.7 1 1 0 1 1 1 1 Collagen triple helix repeat (20 copies) TPR_14 PF13428.6 CBK23506.2 - 1.2e-29 100.5 17.8 5.8e-05 23.6 0.1 12.3 8 6 6 14 14 14 8 Tetratricopeptide repeat TPR_19 PF14559.6 CBK23506.2 - 1.7e-25 89.3 5.1 4.6e-05 23.8 0.6 7.6 7 0 0 7 7 7 5 Tetratricopeptide repeat PRP1_N PF06424.12 CBK23506.2 - 3.2e-11 43.8 1.7 3.2e-11 43.8 1.7 1.9 2 0 0 2 2 1 1 PRP1 splicing factor, N-terminal TPR_2 PF07719.17 CBK23506.2 - 3.2e-09 36.2 10.7 0.015 15.4 0.4 7.3 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_17 PF13431.6 CBK23506.2 - 4.7e-09 36.0 7.8 0.22 12.0 0.3 8.0 8 1 0 8 8 6 2 Tetratricopeptide repeat TPR_16 PF13432.6 CBK23506.2 - 5.1e-09 36.6 13.2 0.036 14.7 0.1 6.8 6 3 2 8 8 7 3 Tetratricopeptide repeat Suf PF05843.14 CBK23506.2 - 9.3e-07 29.1 0.0 0.022 14.8 0.0 3.8 3 2 2 5 5 5 2 Suppressor of forked protein (Suf) TPR_11 PF13414.6 CBK23506.2 - 8.2e-06 25.4 3.5 0.22 11.2 0.0 6.1 6 2 2 8 8 7 1 TPR repeat TPR_9 PF13371.6 CBK23506.2 - 3e-05 24.1 2.3 0.25 11.5 0.0 4.6 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_8 PF13181.6 CBK23506.2 - 0.00056 19.9 12.5 0.023 14.9 0.4 6.5 8 0 0 8 8 7 1 Tetratricopeptide repeat FAT PF02259.23 CBK23506.2 - 0.0014 18.0 8.0 0.17 11.1 0.1 3.9 3 1 1 4 4 4 2 FAT domain TPR_12 PF13424.6 CBK23506.2 - 0.002 18.4 5.6 0.91 9.9 0.2 5.0 5 0 0 5 5 4 1 Tetratricopeptide repeat NRDE-2 PF08424.10 CBK23506.2 - 0.0032 16.6 12.0 0.051 12.7 0.3 4.7 4 2 1 5 5 5 2 NRDE-2, necessary for RNA interference NARP1 PF12569.8 CBK23506.2 - 0.0037 16.2 0.1 6.6 5.5 0.0 4.0 3 1 2 5 5 5 1 NMDA receptor-regulated protein 1 RPN7 PF10602.9 CBK23506.2 - 0.0049 16.6 3.1 0.39 10.4 0.1 3.5 4 0 0 4 4 4 1 26S proteasome subunit RPN7 TPR_1 PF00515.28 CBK23506.2 - 0.0073 16.1 7.4 0.093 12.6 0.4 4.8 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_6 PF13174.6 CBK23506.2 - 0.0091 16.6 11.4 0.57 10.9 0.6 6.4 6 1 0 6 6 5 1 Tetratricopeptide repeat HAT PF02184.16 CBK23506.2 - 0.022 14.7 0.1 34 4.5 0.0 4.1 4 0 0 4 4 4 0 HAT (Half-A-TPR) repeat Mad3_BUB1_I PF08311.12 CBK23506.2 - 0.028 14.4 1.4 1.4 8.9 0.0 4.1 4 1 1 5 5 5 0 Mad3/BUB1 homology region 1 DUF3808 PF10300.9 CBK23506.2 - 0.059 12.1 2.1 10 4.7 0.0 4.2 4 1 0 5 5 5 0 Protein of unknown function (DUF3808) TPR_7 PF13176.6 CBK23506.2 - 0.07 13.2 1.6 2 8.6 0.6 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat APG6_N PF17675.1 CBK23506.2 - 0.31 11.6 3.0 1.4 9.4 3.0 2.1 1 0 0 1 1 1 0 Apg6 coiled-coil region Cadherin PF00028.17 CBK23507.2 - 6.3e-80 263.7 20.1 6.1e-11 42.6 0.5 14.5 14 0 0 14 14 14 13 Cadherin domain TIG PF01833.24 CBK23507.2 - 3.7e-54 180.7 63.4 4.6e-11 42.6 0.6 14.3 13 0 0 13 13 13 10 IPT/TIG domain Cadherin_4 PF17803.1 CBK23507.2 - 4.2e-09 36.9 35.9 0.0015 19.1 0.1 11.0 11 1 0 11 11 11 5 Bacterial cadherin-like domain Big_9 PF17963.1 CBK23507.2 - 6.1e-07 30.1 35.9 0.0072 17.1 0.2 11.0 12 0 0 12 12 12 2 Bacterial Ig domain UPF0242 PF06785.11 CBK23507.2 - 0.031 14.4 1.1 0.11 12.5 1.1 1.9 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Cadherin_3 PF16184.5 CBK23507.2 - 0.17 11.9 10.0 4.1 7.4 0.1 5.5 6 0 0 6 6 6 0 Cadherin-like Ephrin_rec_like PF07699.13 CBK23507.2 - 1.6 8.5 7.1 2.2 8.1 0.6 2.9 2 0 0 2 2 2 0 Putative ephrin-receptor like ApeC PF16977.5 CBK23508.2 - 2.3e-23 83.2 249.8 0.31 10.9 1.7 32.6 12 9 8 32 32 32 31 C-terminal domain of apextrin EpmC PF04315.12 CBK23508.2 - 2.1e-15 56.8 4.4 26 4.5 0.0 17.9 20 0 0 20 20 20 3 Elongation factor P hydroxylase DHHC PF01529.20 CBK23509.2 - 0.048 13.8 0.3 0.071 13.2 0.3 1.3 1 0 0 1 1 1 0 DHHC palmitoyltransferase tRNA-synt_His PF13393.6 CBK23510.2 - 5.5e-28 98.1 0.0 9.9e-28 97.3 0.0 1.3 1 0 0 1 1 1 1 Histidyl-tRNA synthetase tRNA-synt_2b PF00587.25 CBK23510.2 - 9.5e-11 42.0 0.0 1.3e-10 41.6 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 CBK23511.2 - 1.4e-09 37.9 0.1 1.9e-09 37.5 0.1 1.1 1 0 0 1 1 1 1 Anticodon binding domain RNA_polI_A34 PF08208.11 CBK23512.2 - 0.00087 19.4 0.1 0.001 19.2 0.1 1.1 1 0 0 1 1 1 1 DNA-directed RNA polymerase I subunit RPA34.5 DUF1132 PF06575.12 CBK23512.2 - 0.094 13.1 0.0 0.099 13.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1132) Brix PF04427.18 CBK23513.2 - 3e-26 92.7 0.2 3e-26 92.7 0.2 1.4 2 0 0 2 2 2 1 Brix domain Draxin PF15550.6 CBK23513.2 - 0.44 10.4 7.3 0.62 9.9 7.3 1.2 1 0 0 1 1 1 0 Draxin 6PF2K PF01591.18 CBK23514.2 - 1.3e-43 148.9 0.0 2e-43 148.3 0.0 1.3 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 CBK23514.2 - 1.3e-32 113.1 0.0 3.4e-32 111.7 0.0 1.6 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) DUF1622 PF07784.11 CBK23514.2 - 0.13 12.2 0.2 0.26 11.2 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1622) AAA_24 PF13479.6 CBK23514.2 - 0.23 11.2 0.0 0.36 10.5 0.0 1.2 1 0 0 1 1 1 0 AAA domain DHDPS PF00701.22 CBK23515.2 - 7e-34 116.9 0.0 8.3e-34 116.6 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family CPSF_A PF03178.15 CBK23516.2 - 3.5e-52 177.7 0.0 5.3e-52 177.1 0.0 1.3 1 0 0 1 1 1 1 CPSF A subunit region MMS1_N PF10433.9 CBK23517.2 - 1.4e-07 30.6 0.0 1.7e-07 30.3 0.0 1.0 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CTV_P33 PF07184.11 CBK23517.2 - 0.15 11.1 0.0 0.18 10.8 0.0 1.1 1 0 0 1 1 1 0 Citrus tristeza virus P33 protein MMS1_N PF10433.9 CBK23518.2 - 4.3e-07 28.9 0.0 6.6e-07 28.3 0.0 1.2 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CBFD_NFYB_HMF PF00808.23 CBK23519.2 - 1e-17 64.2 1.9 9e-12 45.1 0.1 2.3 2 0 0 2 2 2 2 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 CBK23519.2 - 4.6e-11 43.2 0.3 8.8e-11 42.3 0.3 1.4 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TAF PF02969.17 CBK23519.2 - 0.023 14.8 0.2 0.086 13.0 0.1 1.8 2 0 0 2 2 2 0 TATA box binding protein associated factor (TAF) Aminotran_4 PF01063.19 CBK23520.2 - 4.5e-30 105.2 0.0 5.7e-30 104.8 0.0 1.1 1 0 0 1 1 1 1 Amino-transferase class IV Thioredoxin PF00085.20 CBK23521.2 - 1.4e-28 98.9 0.3 1.3e-13 50.8 0.0 2.4 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_2 PF13098.6 CBK23521.2 - 5.8e-07 29.9 0.6 0.0037 17.7 0.0 2.9 3 0 0 3 3 3 2 Thioredoxin-like domain Thioredoxin_6 PF13848.6 CBK23521.2 - 6.7e-07 29.4 3.8 3.6e-05 23.7 0.5 2.4 2 0 0 2 2 2 2 Thioredoxin-like domain AhpC-TSA PF00578.21 CBK23521.2 - 2.6e-05 24.1 0.2 0.29 11.0 0.0 2.6 2 0 0 2 2 2 2 AhpC/TSA family Thioredoxin_7 PF13899.6 CBK23521.2 - 0.00035 20.7 0.5 1.3 9.2 0.0 3.1 3 0 0 3 3 3 2 Thioredoxin-like Thioredoxin_8 PF13905.6 CBK23521.2 - 0.00072 19.8 3.2 0.078 13.3 0.0 3.5 3 1 1 4 4 4 1 Thioredoxin-like Thioredoxin_3 PF13192.6 CBK23521.2 - 0.006 16.6 0.0 4.4 7.4 0.0 2.5 2 0 0 2 2 2 2 Thioredoxin domain OST3_OST6 PF04756.13 CBK23521.2 - 0.024 14.0 0.2 7 5.9 0.1 2.2 2 0 0 2 2 2 0 OST3 / OST6 family, transporter family Thioredoxin_4 PF13462.6 CBK23521.2 - 0.04 14.1 0.6 1.4 9.1 0.1 2.5 2 0 0 2 2 2 0 Thioredoxin SCO1-SenC PF02630.14 CBK23521.2 - 0.1 12.5 0.1 0.49 10.3 0.0 2.0 2 0 0 2 2 2 0 SCO1/SenC Sas10 PF09368.10 CBK23522.2 - 4.7e-25 87.9 6.5 4.7e-25 87.9 6.5 2.5 2 0 0 2 2 2 1 Sas10 C-terminal domain Sas10_Utp3 PF04000.15 CBK23522.2 - 7.6e-05 23.3 0.1 7.6e-05 23.3 0.1 2.4 3 1 0 3 3 3 1 Sas10/Utp3/C1D family S_100 PF01023.19 CBK23522.2 - 0.02 14.6 0.0 0.18 11.6 0.1 2.2 2 0 0 2 2 2 0 S-100/ICaBP type calcium binding domain SR-25 PF10500.9 CBK23523.2 - 0.47 10.0 12.5 0.028 14.0 7.1 1.6 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Utp11 PF03998.13 CBK23524.2 - 8e-51 173.3 29.5 9.2e-51 173.1 29.5 1.0 1 0 0 1 1 1 1 Utp11 protein SLATT_5 PF18160.1 CBK23524.2 - 0.04 13.2 9.4 0.057 12.7 0.4 2.5 3 0 0 3 3 3 0 SMODS and SLOG-associating 2TM effector domain family 5 ChuX_HutX PF06228.13 CBK23524.2 - 0.044 13.5 0.1 0.07 12.9 0.1 1.5 1 1 0 1 1 1 0 Haem utilisation ChuX/HutX ACR_tran PF00873.19 CBK23524.2 - 0.37 8.4 8.0 2.5 5.6 3.3 2.0 2 0 0 2 2 2 0 AcrB/AcrD/AcrF family Serinc PF03348.15 CBK23525.2 - 1.8e-30 106.3 32.1 3.1e-30 105.5 32.1 1.4 1 1 0 1 1 1 1 Serine incorporator (Serinc) DUF3043 PF11241.8 CBK23525.2 - 2.7 8.0 0.0 2.7 8.0 0.0 3.5 4 1 1 5 5 5 0 Protein of unknown function (DUF3043) Ni_hydr_CYTB PF01292.20 CBK23525.2 - 7.9 6.0 19.6 0.31 10.6 0.2 3.4 3 2 0 3 3 3 0 Prokaryotic cytochrome b561 Fis1_TPR_C PF14853.6 CBK23526.2 - 2.1e-15 56.5 1.0 2.1e-15 56.5 1.0 1.7 2 0 0 2 2 2 1 Fis1 C-terminal tetratricopeptide repeat Fis1_TPR_N PF14852.6 CBK23526.2 - 1.7e-10 40.4 0.0 2.9e-10 39.6 0.0 1.4 1 0 0 1 1 1 1 Fis1 N-terminal tetratricopeptide repeat TPR_2 PF07719.17 CBK23526.2 - 3.2e-05 23.7 5.9 5.8e-05 22.9 0.3 3.1 3 1 0 3 3 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 CBK23526.2 - 4.1e-05 23.4 1.9 0.0013 18.8 0.1 3.0 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.6 CBK23526.2 - 0.00023 21.6 0.5 0.42 11.3 0.1 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat COPI_C PF06957.11 CBK23526.2 - 0.013 14.3 0.1 0.015 14.0 0.1 1.2 1 0 0 1 1 1 0 Coatomer (COPI) alpha subunit C-terminus ANAPC3 PF12895.7 CBK23526.2 - 0.027 14.7 0.7 0.06 13.6 0.5 1.6 1 1 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.6 CBK23526.2 - 0.035 14.5 0.6 49 4.6 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat SRP_TPR_like PF17004.5 CBK23526.2 - 0.048 13.7 0.4 0.088 12.8 0.4 1.7 1 1 0 1 1 1 0 Putative TPR-like repeat TPR_1 PF00515.28 CBK23526.2 - 0.049 13.5 3.2 0.1 12.4 0.4 2.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.6 CBK23526.2 - 0.051 14.1 0.4 0.051 14.1 0.4 2.3 2 1 1 3 3 3 0 Tetratricopeptide repeat Mito_carr PF00153.27 CBK23527.2 - 2.8e-41 139.3 2.2 4.1e-15 55.5 0.0 3.4 3 1 0 3 3 3 3 Mitochondrial carrier protein ETF_QO PF05187.13 CBK23528.2 - 9.6e-29 99.6 0.3 1.5e-28 98.9 0.3 1.3 1 0 0 1 1 1 1 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S DAO PF01266.24 CBK23528.2 - 9.9e-11 41.8 0.4 2.3e-05 24.2 0.5 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 CBK23528.2 - 1.3e-09 37.7 0.6 6.7e-05 22.1 0.7 2.1 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 CBK23528.2 - 8.8e-06 25.9 0.1 7.8e-05 22.8 0.0 2.6 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 CBK23528.2 - 3e-05 23.4 0.1 0.0013 18.0 0.1 2.1 2 0 0 2 2 2 1 Thi4 family GMC_oxred_N PF00732.19 CBK23528.2 - 3.4e-05 23.4 0.0 0.011 15.2 0.0 2.2 2 0 0 2 2 2 2 GMC oxidoreductase Pyr_redox_2 PF07992.14 CBK23528.2 - 7.7e-05 22.1 0.1 0.00027 20.3 0.1 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 CBK23528.2 - 9.4e-05 21.6 0.3 0.00015 20.9 0.3 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_3 PF01494.19 CBK23528.2 - 0.00021 20.6 0.0 0.00083 18.7 0.0 1.8 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.6 CBK23528.2 - 0.00072 18.9 0.9 0.0034 16.7 0.5 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 CBK23528.2 - 0.00097 17.9 1.8 0.0011 17.7 0.4 1.9 3 0 0 3 3 3 1 HI0933-like protein NAD_binding_9 PF13454.6 CBK23528.2 - 0.0019 18.2 0.0 0.0037 17.3 0.0 1.5 1 0 0 1 1 1 1 FAD-NAD(P)-binding FAD_oxidored PF12831.7 CBK23528.2 - 0.0021 17.5 0.0 0.003 17.0 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Fer4_9 PF13187.6 CBK23528.2 - 0.0026 17.9 0.7 0.005 17.0 0.7 1.5 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_7 PF12838.7 CBK23528.2 - 0.0035 17.9 1.6 0.0081 16.7 1.6 1.6 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_21 PF14697.6 CBK23528.2 - 0.072 13.2 0.5 0.16 12.1 0.5 1.6 1 0 0 1 1 1 0 4Fe-4S dicluster domain SAM_2 PF07647.17 CBK23528.2 - 0.076 13.1 0.0 0.17 12.0 0.0 1.5 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) Trp_halogenase PF04820.14 CBK23528.2 - 0.18 10.6 0.2 0.56 9.0 0.3 1.7 2 0 0 2 2 2 0 Tryptophan halogenase Fer4_10 PF13237.6 CBK23528.2 - 0.19 11.9 2.3 0.27 11.4 1.1 1.9 2 0 0 2 2 2 0 4Fe-4S dicluster domain Fer4_4 PF12800.7 CBK23528.2 - 3.7 8.3 5.2 1.5 9.5 2.0 2.1 2 0 0 2 2 1 0 4Fe-4S binding domain Fer4 PF00037.27 CBK23528.2 - 4.4 7.3 6.7 0.27 11.1 0.9 2.1 3 0 0 3 3 3 0 4Fe-4S binding domain MscL PF01741.18 CBK23529.2 - 0.0037 17.6 0.0 0.0041 17.4 0.0 1.2 1 0 0 1 1 1 1 Large-conductance mechanosensitive channel, MscL FAM176 PF14851.6 CBK23529.2 - 0.0046 16.6 0.4 0.0055 16.4 0.4 1.2 1 0 0 1 1 1 1 FAM176 family SID-1_RNA_chan PF13965.6 CBK23529.2 - 0.0074 14.8 0.1 0.0084 14.6 0.1 1.0 1 0 0 1 1 1 1 dsRNA-gated channel SID-1 Connexin PF00029.19 CBK23529.2 - 0.018 14.8 0.1 0.021 14.6 0.1 1.0 1 0 0 1 1 1 0 Connexin DUF4446 PF14584.6 CBK23529.2 - 0.022 14.8 0.1 0.025 14.6 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) OSTbeta PF15048.6 CBK23529.2 - 0.023 14.8 0.0 0.028 14.6 0.0 1.1 1 0 0 1 1 1 0 Organic solute transporter subunit beta protein OAD_gamma PF04277.13 CBK23529.2 - 0.061 13.9 0.1 0.088 13.4 0.1 1.4 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain DUF4381 PF14316.6 CBK23529.2 - 0.097 12.9 0.0 0.11 12.7 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) LapA_dom PF06305.11 CBK23529.2 - 0.12 12.2 0.0 0.17 11.7 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain WGG PF10273.9 CBK23530.2 - 5.4e-11 43.0 0.6 9.4e-11 42.2 0.6 1.3 1 0 0 1 1 1 1 Pre-rRNA-processing protein TSR2 Abhydrolase_6 PF12697.7 CBK23531.2 - 8.8e-07 29.8 0.1 1.6e-06 28.9 0.0 1.7 2 1 0 2 2 2 1 Alpha/beta hydrolase family PGAP1 PF07819.13 CBK23531.2 - 0.00021 21.1 0.4 0.0014 18.4 0.4 1.9 1 1 0 1 1 1 1 PGAP1-like protein DUF676 PF05057.14 CBK23531.2 - 0.0019 17.7 0.2 0.019 14.5 0.2 2.0 1 1 0 1 1 1 1 Putative serine esterase (DUF676) LCAT PF02450.15 CBK23531.2 - 0.18 10.9 0.0 0.23 10.6 0.0 1.1 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase zf-RING_2 PF13639.6 CBK23533.2 - 1.1e-10 41.7 12.2 2.3e-10 40.7 12.2 1.6 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 CBK23533.2 - 3.3e-06 27.3 12.5 8.1e-06 26.0 12.5 1.8 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_11 PF17123.5 CBK23533.2 - 2.8e-05 23.7 10.1 2.8e-05 23.7 10.1 2.1 2 0 0 2 2 2 1 RING-like zinc finger zf-ANAPC11 PF12861.7 CBK23533.2 - 4.8e-05 23.3 5.4 0.00012 22.1 5.4 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_2 PF13923.6 CBK23533.2 - 5.4e-05 23.0 11.5 0.0001 22.1 11.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CBK23533.2 - 8.2e-05 22.5 11.2 0.00016 21.6 11.2 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 CBK23533.2 - 8.5e-05 22.3 8.8 0.00016 21.5 8.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CBK23533.2 - 0.00014 21.8 7.3 0.00025 21.0 4.9 2.3 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4 PF00097.25 CBK23533.2 - 0.00016 21.4 13.1 0.00036 20.3 13.1 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 CBK23533.2 - 0.0014 18.2 9.5 0.0028 17.2 9.5 1.4 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type Prok-RING_4 PF14447.6 CBK23533.2 - 0.0021 17.8 10.9 0.0033 17.2 4.9 2.4 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 Rtf2 PF04641.12 CBK23533.2 - 0.0075 15.7 0.4 0.01 15.2 0.4 1.2 1 0 0 1 1 1 1 Rtf2 RING-finger FANCL_C PF11793.8 CBK23533.2 - 0.032 14.4 11.9 0.3 11.3 11.9 2.3 1 1 0 1 1 1 0 FANCL C-terminal domain zf-HC5HC2H PF13771.6 CBK23533.2 - 0.15 12.4 4.7 1.1 9.6 5.1 2.1 1 1 1 2 2 2 0 PHD-like zinc-binding domain RINGv PF12906.7 CBK23533.2 - 0.16 12.1 12.0 0.34 11.1 11.0 2.0 2 0 0 2 2 2 0 RING-variant domain zinc-ribbons_6 PF07191.12 CBK23533.2 - 0.52 10.3 3.9 0.94 9.5 3.9 1.4 1 0 0 1 1 1 0 zinc-ribbons DUF3953 PF13129.6 CBK23533.2 - 0.67 9.8 11.8 0.3 10.9 0.4 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3953) zinc_ribbon_16 PF17034.5 CBK23533.2 - 0.94 9.7 5.8 2 8.6 5.8 1.5 1 1 0 1 1 1 0 Zinc-ribbon like family zf-RING-like PF08746.11 CBK23533.2 - 1.6 9.1 11.2 4.7 7.6 11.2 1.9 1 1 0 1 1 1 0 RING-like domain DUF3671 PF12420.8 CBK23533.2 - 5.7 7.1 16.0 0.97 9.5 9.3 2.3 1 1 1 2 2 2 0 Protein of unknown function Zf_RING PF16744.5 CBK23533.2 - 6.9 6.9 8.6 19 5.5 8.6 1.7 1 1 0 1 1 1 0 KIAA1045 RING finger DUF1218 PF06749.12 CBK23533.2 - 7.2 7.2 8.2 1.4 9.5 3.0 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1218) zf-C3HC4_4 PF15227.6 CBK23533.2 - 7.3 6.8 9.2 1.7e+02 2.5 0.2 2.7 1 1 2 3 3 3 0 zinc finger of C3HC4-type, RING RRM_1 PF00076.22 CBK23534.2 - 7.9e-31 105.7 0.4 1.1e-15 57.2 0.1 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CBK23534.2 - 6.5e-10 39.0 0.1 4.4e-05 23.5 0.0 2.8 2 2 0 2 2 2 2 RNA recognition motif PGI PF00342.19 CBK23535.2 - 6e-199 661.7 0.0 6.9e-199 661.5 0.0 1.0 1 0 0 1 1 1 1 Phosphoglucose isomerase Lysine_decarbox PF03641.14 CBK23536.2 - 6e-12 45.8 0.0 6.7e-12 45.6 0.0 1.0 1 0 0 1 1 1 1 Possible lysine decarboxylase LDcluster4 PF18306.1 CBK23536.2 - 2.8e-06 27.0 0.0 3e-06 26.9 0.0 1.2 1 0 0 1 1 1 1 SLOG cluster4 family TssC PF17541.2 CBK23536.2 - 0.18 10.6 0.1 0.4 9.4 0.0 1.5 1 1 0 1 1 1 0 Type VI secretion system, TssC, VipB RRM_2 PF04059.12 CBK23537.2 - 3.2e-08 33.7 0.0 5.1e-08 33.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif 2 RRM_1 PF00076.22 CBK23537.2 - 1.2e-05 25.0 0.0 2e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ank_2 PF12796.7 CBK23538.2 - 1.4e-21 76.8 4.2 1.2e-11 45.0 1.8 2.5 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 CBK23538.2 - 1.7e-21 76.0 9.4 6.7e-08 32.7 1.0 5.2 3 1 2 5 5 5 4 Ankyrin repeats (many copies) Ank_4 PF13637.6 CBK23538.2 - 2.5e-20 72.6 2.5 1.6e-09 38.1 0.4 4.5 1 1 4 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 CBK23538.2 - 1.8e-17 61.6 6.4 0.016 15.7 0.0 5.7 6 0 0 6 6 6 5 Ankyrin repeat Ank PF00023.30 CBK23538.2 - 1.3e-14 53.8 8.7 0.0053 17.2 0.0 5.3 6 0 0 6 6 6 4 Ankyrin repeat Shikimate_DH PF01488.20 CBK23538.2 - 0.029 14.4 0.0 0.071 13.2 0.0 1.6 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Glyco_trans_4_5 PF16994.5 CBK23538.2 - 0.12 12.0 0.1 0.35 10.5 0.1 1.8 1 1 0 1 1 1 0 Glycosyl-transferase family 4 Alpha_adaptin_C PF02296.16 CBK23539.2 - 0.064 13.5 0.2 0.24 11.6 0.2 1.9 1 0 0 1 1 1 0 Alpha adaptin AP2, C-terminal domain CAC1F_C PF16885.5 CBK23539.2 - 0.2 11.3 11.5 0.33 10.6 11.5 1.3 1 0 0 1 1 1 0 Voltage-gated calcium channel subunit alpha, C-term PAP1 PF08601.10 CBK23539.2 - 0.33 10.6 22.3 0.54 9.9 22.3 1.3 1 0 0 1 1 1 0 Transcription factor PAP1 SOBP PF15279.6 CBK23539.2 - 0.56 10.8 12.0 1 9.9 12.0 1.4 1 0 0 1 1 1 0 Sine oculis-binding protein BAF1_ABF1 PF04684.13 CBK23539.2 - 0.65 9.0 17.8 0.95 8.4 17.8 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Glyco_hydro_9 PF00759.19 CBK23539.2 - 0.73 9.2 12.2 0.25 10.7 9.4 1.5 2 0 0 2 2 2 0 Glycosyl hydrolase family 9 DUF966 PF06136.13 CBK23539.2 - 0.77 9.4 14.6 1.2 8.7 14.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF966) SID-1_RNA_chan PF13965.6 CBK23539.2 - 1.2 7.5 8.1 1.8 6.9 8.1 1.2 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 FSA_C PF10479.9 CBK23539.2 - 2.6 6.1 17.2 3.9 5.5 17.2 1.3 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus GREB1 PF15782.5 CBK23539.2 - 4.9 4.1 19.9 6.6 3.7 19.9 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer MORN_2 PF07661.13 CBK23541.2 - 0.00037 20.4 3.7 0.14 12.4 0.0 3.6 3 0 0 3 3 3 2 MORN repeat variant DUF4362 PF14275.6 CBK23541.2 - 0.048 13.9 2.9 0.073 13.4 0.1 2.4 2 1 1 3 3 3 0 Domain of unknown function (DUF4362) IlvGEDA_leader PF08046.11 CBK23541.2 - 0.66 9.5 3.7 1 8.9 3.7 1.2 1 0 0 1 1 1 0 IlvGEDA operon leader peptide Arm PF00514.23 CBK23542.2 - 1.9e-58 192.8 22.1 4.1e-13 48.9 0.1 8.4 8 1 0 8 8 8 7 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 CBK23542.2 - 4.2e-20 71.8 0.2 0.00075 19.9 0.0 5.8 4 2 1 5 5 5 5 HEAT-like repeat HEAT PF02985.22 CBK23542.2 - 5e-17 60.5 3.2 0.0021 18.2 0.0 7.1 7 0 0 7 7 7 4 HEAT repeat HEAT_2 PF13646.6 CBK23542.2 - 4.5e-16 59.0 0.0 1.9e-05 25.0 0.0 4.5 2 1 3 5 5 5 4 HEAT repeats Atx10homo_assoc PF09759.9 CBK23542.2 - 4.6e-07 29.8 5.2 0.00055 19.9 0.0 4.9 3 1 2 6 6 6 1 Spinocerebellar ataxia type 10 protein domain Arm_2 PF04826.13 CBK23542.2 - 7.6e-07 28.8 0.1 0.12 11.8 0.0 3.1 1 1 2 3 3 3 3 Armadillo-like Cnd1 PF12717.7 CBK23542.2 - 9.6e-06 25.7 0.1 0.19 11.8 0.0 3.5 1 1 2 3 3 3 1 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 CBK23542.2 - 3e-05 22.8 0.2 0.012 14.2 0.3 2.4 1 1 1 2 2 2 2 Adaptin N terminal region Arm_3 PF16186.5 CBK23542.2 - 8.1e-05 22.1 0.1 0.00079 18.9 1.1 2.1 2 0 0 2 2 2 1 Atypical Arm repeat V-ATPase_H_C PF11698.8 CBK23542.2 - 0.00074 19.6 0.0 0.14 12.3 0.0 3.3 3 0 0 3 3 3 1 V-ATPase subunit H RICTOR_V PF14668.6 CBK23542.2 - 0.0012 19.0 3.3 14 6.0 0.0 4.6 3 2 2 5 5 5 0 Rapamycin-insensitive companion of mTOR, domain 5 V-ATPase_H_N PF03224.14 CBK23542.2 - 0.012 14.9 0.2 0.086 12.1 0.1 2.2 1 1 1 2 2 2 0 V-ATPase subunit H UNC45-central PF11701.8 CBK23542.2 - 0.014 15.3 0.7 7.4 6.5 0.1 3.2 2 1 1 3 3 3 0 Myosin-binding striated muscle assembly central DNA_pol_phi PF04931.13 CBK23542.2 - 0.025 12.7 0.0 3.1 5.8 0.0 2.3 2 0 0 2 2 2 0 DNA polymerase phi HEAT_PBS PF03130.16 CBK23542.2 - 0.06 14.1 0.2 7.9 7.5 0.0 4.1 5 0 0 5 5 4 0 PBS lyase HEAT-like repeat ABC_tran PF00005.27 CBK23544.2 - 2.1e-05 25.1 0.0 2.6e-05 24.8 0.0 1.0 1 0 0 1 1 1 1 ABC transporter Thioredoxin PF00085.20 CBK23545.2 - 9.2e-26 89.8 0.0 1.6e-25 89.1 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_7 PF13899.6 CBK23545.2 - 0.00085 19.5 0.0 0.0017 18.5 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.6 CBK23545.2 - 0.00089 19.7 0.1 0.01 16.3 0.1 2.3 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_6 PF13848.6 CBK23545.2 - 0.0094 15.9 0.0 0.019 14.9 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 CBK23545.2 - 0.017 15.4 0.0 1.2 9.5 0.0 2.6 2 1 1 3 3 3 0 Thioredoxin-like OST3_OST6 PF04756.13 CBK23545.2 - 0.021 14.2 0.0 0.027 13.8 0.0 1.3 1 0 0 1 1 1 0 OST3 / OST6 family, transporter family FAM176 PF14851.6 CBK23545.2 - 0.03 14.0 0.0 0.05 13.3 0.0 1.4 1 0 0 1 1 1 0 FAM176 family HyaE PF07449.11 CBK23545.2 - 0.041 13.9 0.0 0.081 12.9 0.0 1.4 1 0 0 1 1 1 0 Hydrogenase-1 expression protein HyaE eIF-3_zeta PF05091.12 CBK23546.2 - 4.1e-102 342.8 3.4 5.3e-102 342.5 3.4 1.1 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) NARG2_C PF10505.9 CBK23546.2 - 0.00015 21.4 0.6 0.051 13.1 0.2 2.4 2 0 0 2 2 2 2 NMDA receptor-regulated gene protein 2 C-terminus Ribosomal_L27 PF01016.19 CBK23547.2 - 3.6e-35 119.8 0.2 4.4e-35 119.6 0.2 1.1 1 0 0 1 1 1 1 Ribosomal L27 protein Pkinase PF00069.25 CBK23548.2 - 5.2e-10 39.1 0.0 9.1e-10 38.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBK23548.2 - 0.0016 17.8 0.0 0.0035 16.7 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CBK23548.2 - 0.011 15.1 0.0 0.017 14.4 0.0 1.3 1 0 0 1 1 1 0 Kinase-like DUF908 PF06012.12 CBK23548.2 - 0.012 15.1 1.0 0.012 15.1 1.0 1.5 2 0 0 2 2 2 0 Domain of Unknown Function (DUF908) DUF4887 PF16228.5 CBK23548.2 - 0.029 14.5 3.8 0.047 13.9 3.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4887) ANTH PF07651.16 CBK23548.2 - 0.12 11.3 0.0 0.21 10.6 0.0 1.3 1 0 0 1 1 1 0 ANTH domain Pkinase_Tyr PF07714.17 CBK23550.2 - 3.2e-65 220.0 0.0 4.3e-65 219.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 CBK23550.2 - 1.6e-54 185.1 0.0 2.1e-54 184.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Haspin_kinase PF12330.8 CBK23550.2 - 0.1 11.5 0.0 0.18 10.7 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain Pkinase_fungal PF17667.1 CBK23550.2 - 0.12 11.1 0.0 2.2 6.9 0.0 2.0 2 0 0 2 2 2 0 Fungal protein kinase PP2C PF00481.21 CBK23553.2 - 1e-46 159.7 0.0 1e-46 159.7 0.0 1.8 2 0 0 2 2 2 1 Protein phosphatase 2C CDC45 PF02724.14 CBK23553.2 - 0.091 11.0 23.2 0.12 10.6 23.2 1.1 1 0 0 1 1 1 0 CDC45-like protein SDA1 PF05285.12 CBK23553.2 - 0.11 11.9 26.2 0.14 11.5 26.2 1.1 1 0 0 1 1 1 0 SDA1 SEEEED PF14797.6 CBK23553.2 - 0.28 11.3 39.4 0.52 10.5 39.4 1.4 1 0 0 1 1 1 0 Serine-rich region of AP3B1, clathrin-adaptor complex Nop14 PF04147.12 CBK23553.2 - 0.3 9.3 23.8 0.36 9.0 23.8 1.1 1 0 0 1 1 1 0 Nop14-like family MFMR_assoc PF16596.5 CBK23553.2 - 1.3 9.5 19.3 2.1 8.8 19.3 1.4 1 0 0 1 1 1 0 Disordered region downstream of MFMR GREB1 PF15782.5 CBK23553.2 - 1.5 5.9 8.2 1.6 5.7 8.2 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer SOBP PF15279.6 CBK23553.2 - 2.2 8.8 8.3 2.9 8.4 8.3 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein Raftlin PF15250.6 CBK23553.2 - 2.3 6.9 12.4 3 6.5 12.4 1.1 1 0 0 1 1 1 0 Raftlin Presenilin PF01080.17 CBK23553.2 - 2.5 6.8 16.6 3.6 6.3 16.6 1.1 1 0 0 1 1 1 0 Presenilin Menin PF05053.13 CBK23553.2 - 3.1 6.1 11.3 3.9 5.7 11.3 1.1 1 0 0 1 1 1 0 Menin Apt1 PF10351.9 CBK23553.2 - 5.1 5.8 17.3 6.5 5.5 17.3 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain HOOK PF05622.12 CBK23554.2 - 1.9e-06 26.4 0.0 1.9e-06 26.4 0.0 4.2 2 1 2 4 4 4 3 HOOK protein CH PF00307.31 CBK23554.2 - 0.0002 21.5 0.0 0.00068 19.8 0.0 2.0 1 0 0 1 1 1 1 Calponin homology (CH) domain BRE1 PF08647.11 CBK23554.2 - 0.017 15.1 7.9 0.017 15.1 7.9 6.8 2 2 3 5 5 5 0 BRE1 E3 ubiquitin ligase Cas6 PF09559.10 CBK23554.2 - 3.5 7.5 11.9 0.049 13.6 0.6 2.9 3 0 0 3 3 3 0 Cas6 Crispr S4 PF01479.25 CBK23555.2 - 1.8e-12 46.8 0.4 1.8e-12 46.8 0.4 2.2 2 0 0 2 2 2 1 S4 domain zf-DBF PF07535.12 CBK23555.2 - 0.11 12.6 0.0 0.26 11.4 0.0 1.6 1 0 0 1 1 1 0 DBF zinc finger RRM_1 PF00076.22 CBK23556.2 - 7e-09 35.4 0.0 8.5e-09 35.1 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Vta1_C PF18097.1 CBK23556.2 - 0.027 14.2 0.0 0.042 13.6 0.0 1.3 1 0 0 1 1 1 0 Vta1 C-terminal domain RRM_5 PF13893.6 CBK23556.2 - 0.087 12.4 0.0 0.092 12.3 0.0 1.0 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.8 CBK23556.2 - 0.16 12.1 0.0 0.17 12.0 0.0 1.1 1 0 0 1 1 1 0 Limkain b1 CoA_binding PF02629.19 CBK23557.2 - 1e-29 103.1 1.6 1e-29 103.1 1.6 2.5 3 0 0 3 3 3 1 CoA binding domain Ligase_CoA PF00549.19 CBK23557.2 - 2.4e-23 82.7 0.1 4.6e-23 81.7 0.1 1.4 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.6 CBK23557.2 - 7e-10 38.8 0.0 1.5e-09 37.8 0.0 1.5 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.6 CBK23557.2 - 6.4e-05 23.4 0.0 0.00014 22.3 0.0 1.6 1 0 0 1 1 1 1 CoA binding domain GFO_IDH_MocA PF01408.22 CBK23557.2 - 0.052 14.4 0.1 0.14 13.0 0.1 1.7 2 0 0 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold PFK PF00365.20 CBK23558.2 - 1.7e-53 181.8 0.1 2.4e-53 181.3 0.1 1.1 1 0 0 1 1 1 1 Phosphofructokinase DAGK_cat PF00781.24 CBK23558.2 - 0.00026 20.6 0.0 0.0007 19.2 0.0 1.7 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain MnmE_helical PF12631.7 CBK23559.2 - 2.8e-47 161.6 4.3 3.7e-47 161.2 4.3 1.2 1 0 0 1 1 1 1 MnmE helical domain TrmE_N PF10396.9 CBK23559.2 - 1.6e-31 109.0 0.0 5.7e-31 107.2 0.0 1.9 1 0 0 1 1 1 1 GTP-binding protein TrmE N-terminus MMR_HSR1 PF01926.23 CBK23559.2 - 2.7e-21 75.8 0.2 5.9e-21 74.7 0.2 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 CBK23559.2 - 3.5e-11 42.9 0.9 7.9e-09 35.2 0.0 2.3 2 0 0 2 2 2 2 Ferrous iron transport protein B RsgA_GTPase PF03193.16 CBK23559.2 - 1.6e-07 31.4 0.7 0.023 14.6 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase ABC_tran PF00005.27 CBK23559.2 - 1.5e-05 25.5 0.4 0.00088 19.8 0.4 2.4 1 1 0 1 1 1 1 ABC transporter Dynamin_N PF00350.23 CBK23559.2 - 0.0001 22.4 0.0 0.00024 21.2 0.0 1.7 1 1 0 1 1 1 1 Dynamin family MMR_HSR1_Xtn PF16897.5 CBK23559.2 - 0.00043 20.3 0.1 0.0013 18.7 0.1 1.8 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain Ras PF00071.22 CBK23559.2 - 0.0012 18.4 0.1 0.012 15.2 0.1 2.2 1 1 0 1 1 1 1 Ras family AAA_24 PF13479.6 CBK23559.2 - 0.0068 16.1 0.0 0.014 15.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain cobW PF02492.19 CBK23559.2 - 0.0089 15.6 0.1 0.047 13.3 0.0 2.0 1 1 1 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_25 PF13481.6 CBK23559.2 - 0.05 13.2 0.2 6 6.4 0.0 2.4 2 0 0 2 2 2 0 AAA domain EIF_2_alpha PF07541.12 CBK23559.2 - 0.051 13.7 0.0 0.46 10.6 0.2 2.2 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 2 alpha subunit CP_ATPgrasp_2 PF14403.6 CBK23559.2 - 0.054 12.4 0.1 0.11 11.4 0.1 1.4 1 0 0 1 1 1 0 Circularly permuted ATP-grasp type 2 GTP_EFTU PF00009.27 CBK23559.2 - 0.071 12.6 2.0 0.18 11.3 0.2 2.4 3 0 0 3 3 3 0 Elongation factor Tu GTP binding domain PduV-EutP PF10662.9 CBK23559.2 - 0.074 12.8 0.2 1 9.1 0.1 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Arf PF00025.21 CBK23559.2 - 0.091 12.2 0.4 5.9 6.3 0.2 2.4 2 0 0 2 2 2 0 ADP-ribosylation factor family AAA_22 PF13401.6 CBK23559.2 - 0.11 12.7 0.7 1.5 9.1 0.0 2.9 2 2 1 3 3 3 0 AAA domain Y_phosphatase PF00102.27 CBK23560.2 - 5e-07 29.5 0.0 6.4e-07 29.2 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.20 CBK23560.2 - 0.00014 21.7 0.0 0.00039 20.2 0.0 1.7 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 CBK23560.2 - 0.0019 18.2 0.0 0.0033 17.4 0.0 1.4 1 0 0 1 1 1 1 Tyrosine phosphatase family PTPlike_phytase PF14566.6 CBK23560.2 - 0.078 13.1 0.1 0.13 12.4 0.1 1.3 1 0 0 1 1 1 0 Inositol hexakisphosphate Myb_DNA-binding PF00249.31 CBK23562.2 - 0.11 12.8 0.3 0.19 12.0 0.3 1.4 1 0 0 1 1 1 0 Myb-like DNA-binding domain NPR3 PF03666.13 CBK23563.2 - 2.9e-17 62.6 4.3 1.5e-16 60.2 4.3 1.9 1 1 0 1 1 1 1 Nitrogen Permease regulator of amino acid transport activity 3 Big_5 PF13205.6 CBK23564.2 - 5.8e-09 36.6 0.2 0.0078 16.9 0.0 4.1 4 1 1 5 5 5 3 Bacterial Ig-like domain DUF1336 PF07059.12 CBK23565.2 - 2.9e-30 106.1 0.0 4.8e-30 105.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1336) RR_TM4-6 PF06459.12 CBK23566.2 - 0.076 12.8 11.2 0.12 12.2 11.2 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 FTZ PF03867.14 CBK23566.2 - 0.15 11.6 1.1 0.28 10.7 1.1 1.4 1 0 0 1 1 1 0 Fushi tarazu (FTZ), N-terminal region Trypan_PARP PF05887.11 CBK23566.2 - 0.16 11.9 10.6 0.37 10.8 10.6 1.6 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) GAGA_bind PF06217.12 CBK23566.2 - 0.94 9.7 8.4 1.3 9.2 8.4 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family CDC45 PF02724.14 CBK23566.2 - 1.7 6.9 13.2 2.5 6.3 13.2 1.2 1 0 0 1 1 1 0 CDC45-like protein Neur_chan_memb PF02932.16 CBK23566.2 - 7.7 6.5 5.2 15 5.6 5.2 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Sec7 PF01369.20 CBK23567.2 - 5.9e-63 211.9 0.9 8.6e-63 211.3 0.9 1.2 1 0 0 1 1 1 1 Sec7 domain Phosphorylase PF00343.20 CBK23569.2 - 1.2e-293 975.8 0.4 1.4e-293 975.6 0.4 1.0 1 0 0 1 1 1 1 Carbohydrate phosphorylase Nicastrin PF05450.15 CBK23571.2 - 0.029 13.9 0.0 0.04 13.4 0.0 1.2 1 0 0 1 1 1 0 Nicastrin Peptidase_M28 PF04389.17 CBK23571.2 - 0.12 12.1 0.0 0.16 11.6 0.0 1.2 1 0 0 1 1 1 0 Peptidase family M28 HSP70 PF00012.20 CBK23572.2 - 1.2e-31 109.6 0.4 1.4e-31 109.4 0.4 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 CBK23572.2 - 5.1e-13 48.5 0.1 8.3e-13 47.8 0.1 1.4 2 0 0 2 2 2 1 MreB/Mbl protein FtsA PF14450.6 CBK23572.2 - 0.0027 18.1 0.0 0.0043 17.4 0.0 1.4 1 0 0 1 1 1 1 Cell division protein FtsA MutL PF13941.6 CBK23572.2 - 0.0034 16.1 0.0 0.0052 15.4 0.0 1.2 1 0 0 1 1 1 1 MutL protein SrfB PF07520.11 CBK23572.2 - 0.0047 14.9 0.2 0.0066 14.4 0.2 1.1 1 0 0 1 1 1 1 Virulence factor SrfB StbA PF06406.11 CBK23572.2 - 0.012 14.9 0.2 0.025 13.8 0.2 1.5 1 1 1 2 2 2 0 StbA protein EutA PF06277.11 CBK23572.2 - 0.013 14.4 0.0 0.016 14.1 0.0 1.2 1 0 0 1 1 1 0 Ethanolamine utilisation protein EutA PilM_2 PF11104.8 CBK23572.2 - 0.017 14.2 0.0 0.024 13.6 0.0 1.2 1 0 0 1 1 1 0 Type IV pilus assembly protein PilM; Ppx-GppA PF02541.16 CBK23572.2 - 0.019 14.4 0.1 0.024 14.1 0.2 1.5 1 1 0 1 1 1 0 Ppx/GppA phosphatase family DDR PF08841.10 CBK23572.2 - 0.024 13.7 0.1 0.032 13.2 0.1 1.3 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain Actin PF00022.19 CBK23572.2 - 0.049 12.2 0.0 0.051 12.2 0.0 1.1 1 0 0 1 1 1 0 Actin DEAD PF00270.29 CBK23573.2 - 1.3e-06 28.3 0.0 1.6e-06 28.0 0.0 1.1 1 0 0 1 1 1 1 DEAD/DEAH box helicase U3_assoc_6 PF08640.11 CBK23574.2 - 0.027 14.5 0.9 0.086 12.9 0.9 1.9 1 0 0 1 1 1 0 U3 small nucleolar RNA-associated protein 6 T3SSipB PF16535.5 CBK23574.2 - 0.091 13.2 0.2 0.091 13.2 0.2 3.3 3 0 0 3 3 3 0 Type III cell invasion protein SipB SpoVT_C PF15714.5 CBK23574.2 - 0.12 12.4 0.1 0.12 12.4 0.1 2.2 2 0 0 2 2 2 0 Stage V sporulation protein T C-terminal, transcription factor CLZ PF16526.5 CBK23574.2 - 0.22 11.9 8.8 2.9 8.3 0.6 2.7 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Med26_C PF15693.5 CBK23574.2 - 1.3 9.1 7.4 0.22 11.7 0.9 2.5 2 0 0 2 2 2 0 Mediator complex subunit 26 C-terminal KCNQ2_u3 PF16642.5 CBK23574.2 - 2.8 9.0 4.4 31 5.6 0.1 2.7 2 0 0 2 2 2 0 Unstructured region on Potassium channel subunit alpha KvLQT2 UPF0242 PF06785.11 CBK23574.2 - 3 7.9 20.3 0.62 10.1 1.9 3.0 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0242) N-terminus XhlA PF10779.9 CBK23574.2 - 10 6.4 9.6 3.2 8.0 2.1 2.7 2 0 0 2 2 2 0 Haemolysin XhlA MCPsignal PF00015.21 CBK23575.2 - 0.037 13.8 0.1 0.047 13.5 0.1 1.2 1 0 0 1 1 1 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Peptidase_M3 PF01432.20 CBK23576.2 - 1.2e-125 420.3 0.0 1.4e-125 420.1 0.0 1.0 1 0 0 1 1 1 1 Peptidase family M3 PMM PF03332.13 CBK23578.2 - 3.7e-94 314.6 0.9 4.9e-94 314.2 0.9 1.2 1 0 0 1 1 1 1 Eukaryotic phosphomannomutase WD40 PF00400.32 CBK23578.2 - 4.7e-15 55.7 18.4 2.6e-05 24.9 0.7 6.6 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBK23578.2 - 1.6e-10 41.1 1.1 0.072 13.4 0.1 4.4 2 1 2 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain Hydrolase_3 PF08282.12 CBK23578.2 - 0.00011 22.1 0.0 0.0034 17.2 0.0 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase CTV_P13 PF06922.11 CBK23578.2 - 0.093 12.8 0.0 0.19 11.8 0.0 1.5 1 0 0 1 1 1 0 Citrus tristeza virus P13 protein HPS3_N PF14761.6 CBK23578.2 - 0.12 11.9 0.0 1.7 8.1 0.0 2.6 3 0 0 3 3 3 0 Hermansky-Pudlak syndrome 3 Ge1_WD40 PF16529.5 CBK23578.2 - 0.15 11.0 3.4 0.97 8.3 0.0 3.3 3 2 1 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein He_PIG PF05345.12 CBK23579.2 - 0.00062 19.9 0.0 0.0017 18.5 0.0 1.7 1 0 0 1 1 1 1 Putative Ig domain DUF4834 PF16118.5 CBK23579.2 - 0.2 12.7 0.7 0.55 11.2 0.7 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) Sushi PF00084.20 CBK23579.2 - 0.27 11.9 4.1 0.33 11.6 0.6 2.6 2 0 0 2 2 2 0 Sushi repeat (SCR repeat) RRM_1 PF00076.22 CBK23580.2 - 6.4e-17 61.1 1.2 0.00028 20.6 0.0 4.4 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_Rrp7 PF17799.1 CBK23580.2 - 0.0015 18.4 0.0 0.0041 16.9 0.0 1.7 1 0 0 1 1 1 1 Rrp7 RRM-like N-terminal domain RRM_7 PF16367.5 CBK23580.2 - 0.0029 17.7 0.4 0.83 9.8 0.0 3.0 2 1 0 2 2 2 2 RNA recognition motif Rad51 PF08423.11 CBK23581.2 - 3.4e-33 115.0 0.1 5.4e-33 114.3 0.1 1.2 1 0 0 1 1 1 1 Rad51 ATPase PF06745.13 CBK23581.2 - 9.2e-10 38.3 0.1 2.9e-09 36.6 0.1 1.8 1 1 0 1 1 1 1 KaiC AAA_25 PF13481.6 CBK23581.2 - 1.1e-09 38.2 0.0 2.2e-09 37.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain RecA PF00154.21 CBK23581.2 - 1.6e-05 24.5 0.2 8.1e-05 22.2 0.0 2.0 2 0 0 2 2 2 1 recA bacterial DNA recombination protein AAA_24 PF13479.6 CBK23581.2 - 2.3e-05 24.2 0.0 4.1e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain PAXNEB PF05625.11 CBK23581.2 - 0.1 11.8 0.4 0.37 9.9 0.1 1.9 2 0 0 2 2 2 0 PAXNEB protein ATP-synt_ab PF00006.25 CBK23583.2 - 4.6e-106 353.2 0.0 6.9e-106 352.7 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_Xtn PF16886.5 CBK23583.2 - 4.7e-37 126.5 0.0 8.4e-37 125.7 0.0 1.4 1 0 0 1 1 1 1 ATPsynthase alpha/beta subunit N-term extension ATP-synt_ab_N PF02874.23 CBK23583.2 - 2.7e-13 50.2 2.2 1e-12 48.4 0.3 2.7 2 0 0 2 2 2 1 ATP synthase alpha/beta family, beta-barrel domain AAA_18 PF13238.6 CBK23583.2 - 0.17 12.5 0.2 0.74 10.4 0.0 2.0 2 0 0 2 2 2 0 AAA domain Ribosomal_L24e PF01246.20 CBK23584.2 - 4e-27 94.2 1.1 4e-27 94.2 1.1 1.6 2 1 0 2 2 2 1 Ribosomal protein L24e Synaptobrevin PF00957.21 CBK23585.2 - 7.9e-11 41.6 0.9 1.8e-10 40.5 0.9 1.5 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.6 CBK23585.2 - 3e-09 36.8 0.1 4.9e-09 36.1 0.1 1.3 1 0 0 1 1 1 1 Regulated-SNARE-like domain Sin3a_C PF16879.5 CBK23586.2 - 1.9e-23 83.6 0.3 2.3e-22 80.1 0.0 2.3 3 0 0 3 3 3 1 C-terminal domain of Sin3a protein Sin3_corepress PF08295.12 CBK23586.2 - 1.7e-20 72.9 0.0 5.6e-20 71.2 0.0 2.0 1 0 0 1 1 1 1 Sin3 family co-repressor PAH PF02671.21 CBK23586.2 - 9.6e-17 60.9 2.1 1.5e-08 34.6 0.1 3.7 3 0 0 3 3 3 2 Paired amphipathic helix repeat YtxC PF08812.11 CBK23586.2 - 0.073 12.7 0.0 0.15 11.6 0.0 1.4 1 0 0 1 1 1 0 YtxC-like family MFS_1 PF07690.16 CBK23587.2 - 5e-31 107.9 5.5 7.8e-31 107.3 5.5 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily OATP PF03137.20 CBK23587.2 - 8.9e-18 63.9 8.4 2.9e-17 62.2 1.1 2.9 1 1 1 2 2 2 2 Organic Anion Transporter Polypeptide (OATP) family Sugar_tr PF00083.24 CBK23587.2 - 4.5e-17 62.1 3.2 4.5e-17 62.1 3.2 1.8 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_3 PF05977.13 CBK23587.2 - 0.021 13.2 0.2 0.032 12.6 0.2 1.2 1 0 0 1 1 1 0 Transmembrane secretion effector DUF4514 PF14986.6 CBK23587.2 - 0.07 13.1 2.1 0.47 10.5 0.1 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF4514) zf-CCCH PF00642.24 CBK23589.2 - 9.6e-09 34.9 12.9 2.1e-05 24.3 2.4 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 CBK23589.2 - 5e-07 29.6 15.2 4.1e-05 23.5 5.2 3.4 2 1 0 2 2 2 2 Zinc finger domain Torus PF16131.5 CBK23589.2 - 1.6e-06 28.8 3.9 0.017 15.8 0.4 2.4 1 1 1 2 2 2 2 Torus domain zf-CCCH_4 PF18044.1 CBK23589.2 - 0.00037 20.2 4.5 0.00037 20.2 4.5 3.0 2 1 0 2 2 2 1 CCCH-type zinc finger zf-CCCH_2 PF14608.6 CBK23589.2 - 0.14 12.7 13.6 1.9 9.1 4.4 2.6 2 0 0 2 2 2 0 RNA-binding, Nab2-type zinc finger zf-CCCH_3 PF15663.5 CBK23589.2 - 0.23 11.7 6.4 19 5.5 6.4 2.3 1 1 0 1 1 1 0 Zinc-finger containing family UDPG_MGDP_dh_N PF03721.14 CBK23591.2 - 9e-50 168.8 0.2 2.2e-49 167.6 0.1 1.6 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh_C PF03720.15 CBK23591.2 - 5.7e-34 116.7 0.2 6.6e-33 113.3 0.2 2.4 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain UDPG_MGDP_dh PF00984.19 CBK23591.2 - 8.4e-31 106.0 0.0 1.7e-30 105.0 0.0 1.6 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain LRR_8 PF13855.6 CBK23592.2 - 0.00013 21.7 0.6 0.00034 20.3 0.6 1.8 1 0 0 1 1 1 1 Leucine rich repeat LRR_4 PF12799.7 CBK23592.2 - 0.0018 18.6 0.2 0.095 13.2 0.3 2.7 2 0 0 2 2 2 1 Leucine Rich repeats (2 copies) MORN PF02493.20 CBK23592.2 - 0.3 11.1 12.0 0.39 10.7 2.3 3.6 3 0 0 3 3 3 0 MORN repeat LRR_1 PF00560.33 CBK23592.2 - 0.31 11.7 1.1 47 5.1 0.0 3.8 4 0 0 4 4 4 0 Leucine Rich Repeat WD40 PF00400.32 CBK23593.2 - 7.3e-17 61.4 8.7 6.1e-05 23.7 0.1 6.1 6 0 0 6 6 6 4 WD domain, G-beta repeat CAF1C_H4-bd PF12265.8 CBK23593.2 - 3.8e-10 39.9 0.2 1.1e-09 38.4 0.1 1.9 2 0 0 2 2 2 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex Dynein_heavy PF03028.15 CBK23593.2 - 0.05 13.7 0.0 0.12 12.4 0.0 1.6 1 0 0 1 1 1 0 Dynein heavy chain region D6 P-loop domain TP6A_N PF04406.14 CBK23594.2 - 0.00078 19.4 0.1 0.0033 17.4 0.0 1.9 2 0 0 2 2 2 1 Type IIB DNA topoisomerase PGM_PMM_I PF02878.16 CBK23595.2 - 6e-14 51.9 0.1 8.6e-09 35.2 0.0 2.5 1 1 1 2 2 2 2 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_IV PF00408.20 CBK23595.2 - 1.5e-10 41.1 0.1 4.5e-10 39.6 0.1 1.8 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain PGM_PMM_III PF02880.16 CBK23595.2 - 3e-07 30.6 0.1 7.6e-07 29.3 0.1 1.8 1 1 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.16 CBK23595.2 - 0.031 14.9 0.1 0.64 10.7 0.1 2.9 2 1 0 2 2 2 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II AcetylCoA_hyd_C PF13336.6 CBK23596.2 - 4.3e-63 211.8 0.0 6.5e-63 211.3 0.0 1.3 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain AcetylCoA_hydro PF02550.15 CBK23596.2 - 9.3e-21 74.7 0.0 1.6e-20 74.0 0.0 1.4 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase N-terminal domain DUF4238 PF14022.6 CBK23597.2 - 0.0081 15.7 0.4 0.011 15.3 0.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4238) Syntaxin-6_N PF09177.11 CBK23597.2 - 0.016 15.7 5.5 0.094 13.3 5.5 1.9 1 1 0 1 1 1 0 Syntaxin 6, N-terminal ISG65-75 PF11727.8 CBK23597.2 - 0.028 13.7 0.2 0.034 13.4 0.2 1.1 1 0 0 1 1 1 0 Invariant surface glycoprotein Cep3 PF16846.5 CBK23597.2 - 0.055 11.9 2.1 0.072 11.5 2.1 1.0 1 0 0 1 1 1 0 Centromere DNA-binding protein complex CBF3 subunit B Hc1 PF07432.13 CBK23597.2 - 0.15 12.5 0.7 0.84 10.0 0.1 2.1 2 0 0 2 2 2 0 Histone H1-like protein Hc1 DUF3552 PF12072.8 CBK23597.2 - 2.8 7.3 6.9 0.33 10.4 0.8 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF3552) ABC_tran PF00005.27 CBK23598.2 - 1.5e-29 103.2 0.0 2.5e-29 102.5 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 CBK23598.2 - 2.2e-07 31.0 1.9 0.00066 19.6 0.1 2.3 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 CBK23598.2 - 0.00026 21.4 0.0 0.00036 20.9 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain SMC_N PF02463.19 CBK23598.2 - 0.0004 19.9 0.6 0.24 10.8 0.0 2.2 1 1 1 2 2 2 2 RecF/RecN/SMC N terminal domain RNA12 PF10443.9 CBK23598.2 - 0.0032 16.3 0.0 0.0044 15.8 0.0 1.1 1 0 0 1 1 1 1 RNA12 protein T2SSE PF00437.20 CBK23598.2 - 0.02 14.0 0.0 0.029 13.4 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_29 PF13555.6 CBK23598.2 - 0.02 14.6 0.1 0.044 13.5 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain SbcCD_C PF13558.6 CBK23598.2 - 0.022 15.0 0.1 0.43 10.8 0.1 2.3 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit RsgA_GTPase PF03193.16 CBK23598.2 - 0.05 13.5 0.0 0.1 12.5 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase NACHT PF05729.12 CBK23598.2 - 0.054 13.4 0.1 0.16 11.9 0.0 1.9 2 0 0 2 2 2 0 NACHT domain AAA_30 PF13604.6 CBK23598.2 - 0.083 12.6 0.0 0.11 12.2 0.0 1.4 1 1 0 1 1 1 0 AAA domain AAA_23 PF13476.6 CBK23598.2 - 0.11 13.0 0.7 0.23 12.0 0.4 1.7 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 CBK23598.2 - 0.11 12.9 0.1 21 5.6 0.0 2.3 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 CBK23598.2 - 0.16 12.2 1.0 2 8.7 1.0 2.3 1 1 0 1 1 1 0 AAA domain SopD PF11047.8 CBK23599.2 - 0.22 10.7 0.1 0.22 10.7 0.1 1.4 2 0 0 2 2 2 0 Salmonella outer protein D TUG-UBL1 PF11470.8 CBK23601.2 - 3.5e-05 23.9 1.8 0.9 9.8 0.0 4.2 4 1 0 4 4 4 2 TUG ubiquitin-like domain Neur_chan_memb PF02932.16 CBK23601.2 - 0.76 9.8 15.7 0.35 10.9 1.8 2.4 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region DUF3752 PF12572.8 CBK23601.2 - 2 8.9 21.8 0.22 12.0 5.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3752) Ras PF00071.22 CBK23602.2 - 8.2e-30 103.5 0.2 8.9e-30 103.4 0.2 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CBK23602.2 - 1.7e-26 92.8 0.1 1.9e-26 92.7 0.1 1.0 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CBK23602.2 - 1.1e-07 31.4 0.0 1.3e-07 31.3 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 CBK23602.2 - 0.00026 21.1 0.0 0.0003 20.8 0.0 1.1 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 CBK23602.2 - 0.00091 18.7 0.0 0.00095 18.6 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 CBK23602.2 - 0.0067 15.9 0.0 0.0078 15.7 0.0 1.0 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit TniB PF05621.11 CBK23602.2 - 0.018 14.5 0.0 0.033 13.6 0.0 1.4 1 1 0 1 1 1 0 Bacterial TniB protein AAA_16 PF13191.6 CBK23602.2 - 0.089 13.2 0.0 0.19 12.1 0.0 1.7 1 1 0 1 1 1 0 AAA ATPase domain Cyclin PF08613.11 CBK23603.2 - 3.1e-28 99.2 1.0 4.3e-28 98.7 1.0 1.2 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 CBK23603.2 - 9.8e-12 44.7 0.2 1.3e-11 44.3 0.2 1.2 1 0 0 1 1 1 1 Cyclin, N-terminal domain V-SNARE_C PF12352.8 CBK23604.2 - 5.1e-07 29.9 0.3 5.1e-07 29.9 0.3 2.5 3 0 0 3 3 3 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.13 CBK23604.2 - 0.00016 21.5 2.4 0.0086 16.0 0.1 2.6 2 1 0 2 2 2 2 Sec20 ABC2_membrane_6 PF06182.11 CBK23604.2 - 0.018 14.8 0.1 0.029 14.1 0.1 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein DUF996 PF06195.13 CBK23604.2 - 0.054 13.8 0.2 0.095 13.0 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF996) NPV_P10 PF05531.12 CBK23604.2 - 0.077 13.5 2.3 0.27 11.7 0.1 2.9 3 1 1 4 4 4 0 Nucleopolyhedrovirus P10 protein DUF3341 PF11821.8 CBK23604.2 - 0.11 12.2 0.0 8.2 6.0 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3341) UDPGP PF01704.18 CBK23605.2 - 1.3e-23 83.3 0.0 1.7e-23 83.0 0.0 1.1 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase DUF3848 PF12959.7 CBK23605.2 - 0.1 12.7 0.4 0.66 10.1 0.0 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3848) Sec62 PF03839.16 CBK23606.2 - 2.5e-17 63.1 0.1 3.2e-17 62.8 0.1 1.2 1 0 0 1 1 1 1 Translocation protein Sec62 RhoGAP PF00620.27 CBK23607.2 - 1e-11 44.9 0.0 2.2e-11 43.8 0.0 1.6 1 0 0 1 1 1 1 RhoGAP domain MyTH4 PF00784.17 CBK23607.2 - 3e-09 37.3 0.1 9.7e-09 35.7 0.0 1.9 2 0 0 2 2 2 1 MyTH4 domain RNA_polI_A14 PF08203.11 CBK23607.2 - 0.012 16.3 0.1 0.59 10.9 0.0 2.7 1 1 0 2 2 2 0 Yeast RNA polymerase I subunit RPA14 SNF2_N PF00176.23 CBK23608.2 - 4.3e-49 167.1 1.0 4.3e-49 167.1 1.0 2.2 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 CBK23608.2 - 2.6e-15 56.7 0.0 7.8e-15 55.2 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 CBK23608.2 - 6.5e-09 36.0 0.0 2.2e-08 34.3 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.29 CBK23608.2 - 0.001 18.8 0.0 0.0023 17.7 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase TFIIA PF03153.13 CBK23608.2 - 0.41 10.6 12.4 0.16 12.0 1.4 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit DUF2052 PF09747.9 CBK23608.2 - 1.9 8.5 14.8 0.057 13.5 5.7 2.3 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) NOA36 PF06524.12 CBK23608.2 - 3.8 6.7 9.8 7.5 5.8 9.8 1.4 1 0 0 1 1 1 0 NOA36 protein Astro_capsid_p PF12226.8 CBK23608.2 - 4.8 6.2 10.1 7.9 5.5 10.1 1.3 1 0 0 1 1 1 0 Turkey astrovirus capsid protein TRAP_alpha PF03896.16 CBK23608.2 - 8.8 5.4 7.4 18 4.4 7.4 1.4 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit RRM_1 PF00076.22 CBK23609.2 - 1.1e-10 41.2 0.1 1.8e-10 40.5 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF3684 PF12449.8 CBK23609.2 - 0.027 12.3 6.2 0.034 11.9 6.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3684) NOA36 PF06524.12 CBK23609.2 - 0.042 13.2 12.9 0.059 12.7 12.9 1.2 1 0 0 1 1 1 0 NOA36 protein SAPS PF04499.15 CBK23609.2 - 0.14 10.9 2.7 0.13 11.0 2.7 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DUF913 PF06025.12 CBK23609.2 - 0.16 10.9 3.9 0.2 10.6 3.9 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Methyltransf_32 PF13679.6 CBK23609.2 - 0.21 11.6 2.8 0.31 11.0 2.8 1.2 1 0 0 1 1 1 0 Methyltransferase domain PPP4R2 PF09184.11 CBK23609.2 - 0.33 10.5 14.1 0.49 9.9 14.1 1.2 1 0 0 1 1 1 0 PPP4R2 CDC45 PF02724.14 CBK23609.2 - 0.38 9.0 20.1 0.45 8.7 20.1 1.1 1 0 0 1 1 1 0 CDC45-like protein PPL5 PF18168.1 CBK23609.2 - 0.73 9.1 7.1 1.1 8.5 7.1 1.3 1 0 0 1 1 1 0 Prim-pol family 5 CDC27 PF09507.10 CBK23609.2 - 0.85 8.9 19.8 1.1 8.6 19.8 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Nop14 PF04147.12 CBK23609.2 - 1 7.5 19.2 1.2 7.2 19.2 1.1 1 0 0 1 1 1 0 Nop14-like family TFB6 PF17110.5 CBK23609.2 - 1.2 8.8 5.9 1.9 8.2 5.9 1.5 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH Cwf_Cwc_15 PF04889.12 CBK23609.2 - 1.3 8.7 28.9 0.029 14.1 22.3 1.5 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein GCIP PF13324.6 CBK23609.2 - 1.3 8.5 5.1 1.8 8.1 5.1 1.2 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting Astro_capsid_p PF12226.8 CBK23609.2 - 1.4 8.0 13.7 1.9 7.5 13.7 1.1 1 0 0 1 1 1 0 Turkey astrovirus capsid protein Pox_Ag35 PF03286.14 CBK23609.2 - 2.6 7.8 17.5 4.5 7.0 17.5 1.3 1 0 0 1 1 1 0 Pox virus Ag35 surface protein DUF4746 PF15928.5 CBK23609.2 - 2.8 7.3 11.0 3.4 7.0 11.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Myc_N PF01056.18 CBK23609.2 - 3.9 7.3 9.4 5.3 6.8 9.4 1.2 1 0 0 1 1 1 0 Myc amino-terminal region CENP-B_dimeris PF09026.10 CBK23609.2 - 4.3 7.8 16.7 8.2 6.9 16.7 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Presenilin PF01080.17 CBK23609.2 - 4.7 5.9 8.2 5.9 5.6 8.2 1.2 1 0 0 1 1 1 0 Presenilin DNA_pol_phi PF04931.13 CBK23609.2 - 5.6 4.9 20.6 7.4 4.5 20.6 1.1 1 0 0 1 1 1 0 DNA polymerase phi RXT2_N PF08595.11 CBK23609.2 - 6.6 6.7 22.7 0.051 13.6 12.3 2.2 2 0 0 2 2 2 0 RXT2-like, N-terminal Sec1 PF00995.23 CBK23610.2 - 1.9e-11 43.9 0.0 3.3e-11 43.2 0.0 1.4 1 1 0 1 1 1 1 Sec1 family P5CR_dimer PF14748.6 CBK23612.2 - 7.4e-36 122.5 0.1 1e-35 122.1 0.1 1.2 1 0 0 1 1 1 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.17 CBK23612.2 - 2.2e-08 34.6 0.0 6e-08 33.2 0.0 1.8 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.15 CBK23612.2 - 0.0005 20.3 0.0 0.00094 19.4 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase UPF0020 PF01170.18 CBK23614.2 - 8.9e-05 22.3 0.0 0.00058 19.6 0.0 2.1 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 SART-1 PF03343.13 CBK23615.2 - 8.4e-22 77.5 4.7 8.9e-16 57.6 1.8 3.4 3 1 0 3 3 3 2 SART-1 family CAP PF00188.26 CBK23615.2 - 0.022 15.6 1.7 5.9 7.7 0.0 3.5 4 0 0 4 4 4 0 Cysteine-rich secretory protein family PAP1 PF08601.10 CBK23615.2 - 5.4 6.6 19.4 9.5 5.8 19.4 1.4 1 0 0 1 1 1 0 Transcription factor PAP1 SART-1 PF03343.13 CBK23616.2 - 1.4e-14 53.6 4.3 1.2e-13 50.6 2.9 1.9 1 1 1 2 2 2 2 SART-1 family Parvo_coat PF00740.18 CBK23616.2 - 0.036 12.7 0.0 0.04 12.6 0.0 1.0 1 0 0 1 1 1 0 Parvovirus coat protein VP2 NopRA1 PF16201.5 CBK23617.2 - 2.2e-43 148.2 3.7 9.7e-43 146.1 1.6 2.8 2 0 0 2 2 2 1 Nucleolar pre-ribosomal-associated protein 1 Connexin PF00029.19 CBK23617.2 - 4.2e-05 23.4 2.0 0.014 15.2 0.1 3.2 3 0 0 3 3 3 2 Connexin CPSF100_C PF13299.6 CBK23617.2 - 0.15 12.3 3.8 2.7 8.1 0.1 2.4 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal BUD22 PF09073.10 CBK23617.2 - 4.6 6.5 18.0 0.39 10.0 1.9 2.3 2 0 0 2 2 2 0 BUD22 TPR_19 PF14559.6 CBK23620.2 - 1.5e-08 35.1 22.0 0.29 11.7 3.1 6.7 6 1 1 7 7 7 5 Tetratricopeptide repeat TPR_14 PF13428.6 CBK23620.2 - 1.7e-08 34.5 20.4 0.017 15.9 0.0 7.6 5 4 5 10 10 10 3 Tetratricopeptide repeat ChAPs PF09295.10 CBK23620.2 - 2.3e-05 23.6 6.9 0.00037 19.6 3.1 2.9 3 1 0 4 4 4 1 ChAPs (Chs5p-Arf1p-binding proteins) TPR_15 PF13429.6 CBK23620.2 - 0.00047 19.5 15.7 0.0058 15.9 1.0 2.8 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 CBK23620.2 - 0.00092 19.8 10.5 0.44 11.2 1.6 4.4 4 1 2 6 6 5 2 Tetratricopeptide repeat TPR_2 PF07719.17 CBK23620.2 - 0.0066 16.5 15.9 3.5 8.0 0.0 7.3 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_12 PF13424.6 CBK23620.2 - 0.011 16.0 8.9 2.5 8.4 0.0 4.8 5 0 0 5 5 5 0 Tetratricopeptide repeat Suf PF05843.14 CBK23620.2 - 0.017 15.1 6.4 0.15 12.0 0.0 2.6 3 0 0 3 3 3 0 Suppressor of forked protein (Suf) Phage_tail_APC PF16778.5 CBK23620.2 - 0.093 12.6 1.4 0.83 9.6 0.4 2.8 2 0 0 2 2 2 0 Phage tail assembly chaperone protein TPR_8 PF13181.6 CBK23620.2 - 0.11 12.7 15.3 0.27 11.6 0.0 6.9 8 0 0 8 8 8 0 Tetratricopeptide repeat NOA36 PF06524.12 CBK23620.2 - 1.4 8.1 3.3 2.2 7.5 3.3 1.3 1 0 0 1 1 1 0 NOA36 protein DUF3381 PF11861.8 CBK23620.2 - 1.8 8.3 8.2 0.084 12.7 0.7 2.5 3 1 0 3 3 3 0 Domain of unknown function (DUF3381) CENP-B_dimeris PF09026.10 CBK23620.2 - 4.1 7.8 8.6 10 6.6 8.6 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Ldh_1_N PF00056.23 CBK23621.2 - 6.3e-41 139.8 0.1 1e-40 139.1 0.1 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.18 CBK23621.2 - 6.5e-37 127.0 0.0 9.1e-37 126.6 0.0 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain 3Beta_HSD PF01073.19 CBK23621.2 - 0.0034 16.4 0.0 0.0049 15.9 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family THF_DHG_CYH_C PF02882.19 CBK23621.2 - 0.013 14.8 0.1 0.084 12.2 0.1 2.0 1 1 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Semialdhyde_dh PF01118.24 CBK23621.2 - 0.084 13.3 0.1 0.26 11.7 0.1 1.9 1 1 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Glyco_hydro_4 PF02056.16 CBK23621.2 - 0.11 12.0 0.6 0.94 9.0 0.3 2.2 1 1 1 2 2 2 0 Family 4 glycosyl hydrolase La PF05383.17 CBK23622.2 - 1.1e-20 73.5 0.3 2.5e-20 72.3 0.3 1.7 1 0 0 1 1 1 1 La domain RRM_1 PF00076.22 CBK23622.2 - 9.8e-05 22.1 0.1 0.00032 20.5 0.0 2.0 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ribosomal_L3 PF00297.22 CBK23623.2 - 4.9e-175 581.9 9.5 5.6e-175 581.7 9.5 1.0 1 0 0 1 1 1 1 Ribosomal protein L3 GST_C_3 PF14497.6 CBK23624.2 - 1.6e-12 47.5 0.7 2.7e-12 46.7 0.7 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 CBK23624.2 - 4.7e-11 42.9 0.0 1.2e-10 41.6 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 CBK23624.2 - 2.5e-07 30.8 0.1 3.9e-07 30.2 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 CBK23624.2 - 8.4e-06 26.1 0.0 1.6e-05 25.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 CBK23624.2 - 1.3e-05 25.4 0.0 3.1e-05 24.2 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 CBK23624.2 - 7.7e-05 22.6 0.0 0.00014 21.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_6 PF17171.4 CBK23624.2 - 0.032 14.0 0.0 0.088 12.6 0.0 1.8 1 1 1 2 2 2 0 Glutathione S-transferase, C-terminal domain Exo_endo_phos PF03372.23 CBK23625.2 - 4.8e-06 26.3 0.1 5.5e-06 26.1 0.1 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.6 CBK23625.2 - 0.0012 18.7 0.0 1.7 8.5 0.0 2.3 2 0 0 2 2 2 2 Endonuclease-reverse transcriptase RNA_pol_Rpb4 PF03874.16 CBK23626.2 - 3.8e-10 40.2 0.0 2.8e-09 37.3 0.0 1.9 1 1 0 1 1 1 1 RNA polymerase Rpb4 CENP-B_N PF04218.13 CBK23626.2 - 0.12 12.1 0.0 0.59 9.8 0.0 2.1 3 0 0 3 3 3 0 CENP-B N-terminal DNA-binding domain Clathrin PF00637.20 CBK23627.2 - 6.1e-17 61.8 10.6 1.6e-11 44.2 1.3 3.1 3 1 0 3 3 3 2 Region in Clathrin and VPS zf-C3H2C3 PF17122.5 CBK23627.2 - 0.00025 21.0 7.5 0.00047 20.1 7.5 1.5 1 0 0 1 1 1 1 Zinc-finger TPR_11 PF13414.6 CBK23627.2 - 0.017 14.8 0.8 0.13 12.0 1.1 2.4 2 0 0 2 2 2 0 TPR repeat C1_1 PF00130.22 CBK23627.2 - 0.065 13.1 2.6 0.18 11.7 2.6 1.7 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-rbx1 PF12678.7 CBK23627.2 - 0.12 12.7 2.1 0.32 11.3 2.1 1.7 1 0 0 1 1 1 0 RING-H2 zinc finger domain TPR_2 PF07719.17 CBK23627.2 - 0.18 12.0 0.2 0.18 12.0 0.2 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat zf-RING_UBOX PF13445.6 CBK23627.2 - 0.22 11.6 7.2 0.68 10.0 7.2 1.9 1 0 0 1 1 1 0 RING-type zinc-finger zf-C3HC4_2 PF13923.6 CBK23627.2 - 0.6 10.0 4.9 1.6 8.6 4.9 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) CheC PF04509.12 CBK23628.2 - 0.13 12.2 0.1 0.69 9.9 0.1 2.3 1 0 0 1 1 1 0 CheC-like family CelTOS PF18659.1 CBK23628.2 - 5.4 7.5 8.6 5.2 7.5 0.6 3.7 3 2 0 3 3 3 0 Cell-traversal protein for ookinetes and sporozoites MAGE_N PF12440.8 CBK23628.2 - 8.9 7.1 12.1 3.9 8.2 8.3 2.3 2 0 0 2 2 2 0 Melanoma associated antigen family N terminal Pyr_redox_2 PF07992.14 CBK23629.2 - 2.6e-52 177.9 0.0 3.2e-52 177.6 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 CBK23629.2 - 6.1e-25 87.6 0.0 1.1e-24 86.8 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 CBK23629.2 - 1.1e-16 61.2 0.5 3.6e-14 53.1 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 CBK23629.2 - 6e-09 35.6 0.0 1.9e-06 27.4 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 CBK23629.2 - 2.2e-05 23.7 1.1 6e-05 22.3 0.9 1.8 3 0 0 3 3 3 1 FAD binding domain FAD_oxidored PF12831.7 CBK23629.2 - 9.7e-05 21.9 4.0 0.0055 16.1 2.8 2.6 2 1 1 3 3 3 1 FAD dependent oxidoreductase GIDA PF01134.22 CBK23629.2 - 0.00022 20.4 0.3 0.00035 19.8 0.3 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A HI0933_like PF03486.14 CBK23629.2 - 0.0011 17.8 0.4 0.0068 15.2 0.2 2.0 2 0 0 2 2 2 1 HI0933-like protein AlaDh_PNT_C PF01262.21 CBK23629.2 - 0.0012 18.2 0.0 0.0059 15.9 0.0 1.9 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain DAO PF01266.24 CBK23629.2 - 0.0012 18.5 0.6 1.6 8.3 0.4 2.5 3 0 0 3 3 3 2 FAD dependent oxidoreductase Thi4 PF01946.17 CBK23629.2 - 0.013 14.8 0.1 0.025 13.8 0.1 1.5 1 0 0 1 1 1 0 Thi4 family NAD_binding_8 PF13450.6 CBK23629.2 - 0.033 14.4 2.8 0.3 11.4 0.5 2.7 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain DUF3932 PF13068.6 CBK23629.2 - 0.13 12.5 0.1 0.25 11.6 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3932) Pribosyltran_N PF13793.6 CBK23630.2 - 1.3e-46 157.2 0.0 4.3e-46 155.6 0.0 1.9 1 0 0 1 1 1 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.6 CBK23630.2 - 2.2e-25 89.8 0.8 4.8e-25 88.6 0.8 1.5 1 0 0 1 1 1 1 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.27 CBK23630.2 - 4.2e-12 45.9 0.2 8.6e-12 44.9 0.2 1.5 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 CBK23630.2 - 0.0065 15.9 0.0 0.011 15.2 0.0 1.3 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Peptidase_M24 PF00557.24 CBK23631.2 - 1.7e-42 145.5 0.7 2.2e-42 145.1 0.7 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 DUF724 PF05266.14 CBK23632.2 - 0.0034 17.2 0.7 0.0034 17.2 0.7 3.3 1 1 0 3 3 3 1 Protein of unknown function (DUF724) FlaF PF07309.11 CBK23632.2 - 0.019 14.9 1.5 0.019 14.9 1.5 3.2 3 0 0 3 3 3 0 Flagellar protein FlaF DUF1202 PF06717.11 CBK23632.2 - 0.082 12.3 0.1 0.47 9.8 0.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1202) Acetyltransf_14 PF03421.16 CBK23632.2 - 0.13 12.3 2.4 0.27 11.3 0.2 2.3 1 1 1 2 2 2 0 YopJ Serine/Threonine acetyltransferase PRKG1_interact PF15898.5 CBK23632.2 - 0.23 12.4 40.9 0.12 13.2 11.6 4.2 2 1 1 3 3 3 0 cGMP-dependent protein kinase interacting domain GCP_N_terminal PF17681.1 CBK23632.2 - 1.1 8.8 8.0 5 6.6 3.9 3.0 2 1 1 3 3 3 0 Gamma tubulin complex component N-terminal Rootletin PF15035.6 CBK23633.2 - 0.0031 17.5 8.5 0.0059 16.6 8.5 1.5 1 0 0 1 1 1 1 Ciliary rootlet component, centrosome cohesion MerR-DNA-bind PF09278.11 CBK23633.2 - 0.022 15.3 2.6 0.022 15.3 2.6 3.3 1 1 1 2 2 2 0 MerR, DNA binding bZIP_1 PF00170.21 CBK23633.2 - 0.14 12.3 9.5 0.22 11.6 0.8 3.2 2 1 1 3 3 3 0 bZIP transcription factor DUF1664 PF07889.12 CBK23633.2 - 0.19 11.8 5.1 1.2 9.2 0.5 2.7 1 1 1 3 3 3 0 Protein of unknown function (DUF1664) Leu_zip PF15294.6 CBK23633.2 - 0.28 10.7 7.6 0.22 11.0 6.2 1.5 1 1 0 1 1 1 0 Leucine zipper ATG16 PF08614.11 CBK23633.2 - 0.32 11.2 21.0 0.25 11.5 7.7 2.5 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) Spc7 PF08317.11 CBK23633.2 - 0.59 9.0 14.2 0.96 8.3 14.2 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein YabA PF06156.13 CBK23633.2 - 1.2 9.8 9.2 8 7.2 1.7 2.6 1 1 1 2 2 2 0 Initiation control protein YabA DUF948 PF06103.11 CBK23633.2 - 1.6 9.0 4.9 15 5.9 0.5 2.9 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) Cnn_1N PF07989.11 CBK23633.2 - 2 8.6 9.2 15 5.9 0.4 2.8 2 0 0 2 2 2 0 Centrosomin N-terminal motif 1 FUSC PF04632.12 CBK23633.2 - 2.3 6.7 12.4 2.8 6.4 12.4 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family SHE3 PF17078.5 CBK23633.2 - 2.6 7.7 6.7 1.4 8.6 3.7 2.0 1 1 1 2 2 2 0 SWI5-dependent HO expression protein 3 Cep57_MT_bd PF06657.13 CBK23633.2 - 2.8 8.5 13.0 3.4 8.2 4.3 2.7 2 1 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 PI3K_P85_iSH2 PF16454.5 CBK23633.2 - 4.3 6.9 11.2 5.6 6.5 1.7 2.4 1 1 1 2 2 2 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain TolA_bind_tri PF16331.5 CBK23633.2 - 4.7 7.4 21.2 0.68 10.1 4.8 2.7 2 0 0 2 2 2 0 TolA binding protein trimerisation CENP-F_leu_zip PF10473.9 CBK23633.2 - 6 6.9 16.8 1.5 8.8 12.8 2.0 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 CENP-H PF05837.12 CBK23633.2 - 6.5 7.2 19.1 13 6.2 4.4 2.5 1 1 1 2 2 2 0 Centromere protein H (CENP-H) DivIC PF04977.15 CBK23633.2 - 9.5 6.1 20.5 0.52 10.1 0.9 2.8 3 0 0 3 3 3 0 Septum formation initiator IFT57 PF10498.9 CBK23633.2 - 9.7 5.0 10.5 6.3 5.7 2.2 2.3 1 1 0 2 2 2 0 Intra-flagellar transport protein 57 RRM_1 PF00076.22 CBK23634.2 - 4.6e-39 132.1 0.1 5.6e-19 67.7 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM PF05172.13 CBK23634.2 - 9.3e-05 22.3 0.0 0.018 15.0 0.0 2.7 2 1 0 2 2 2 2 Nup53/35/40-type RNA recognition motif Nup35_RRM_2 PF14605.6 CBK23634.2 - 0.0098 15.9 0.0 5.7 7.0 0.0 2.4 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif RRM_7 PF16367.5 CBK23634.2 - 0.067 13.3 0.1 3.3 7.9 0.0 2.7 2 2 0 2 2 2 0 RNA recognition motif Cgr1 PF03879.14 CBK23635.2 - 4.1e-07 30.4 23.8 4.1e-07 30.4 23.8 1.6 2 0 0 2 2 2 1 Cgr1 family DUF2963 PF11178.8 CBK23635.2 - 0.27 11.0 4.2 0.3 10.8 2.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2963) PGC7_Stella PF15549.6 CBK23635.2 - 0.49 10.4 13.5 0.57 10.1 13.5 1.2 1 0 0 1 1 1 0 PGC7/Stella/Dppa3 domain DASH_Dad4 PF08650.10 CBK23636.2 - 4e-13 49.1 1.7 4.4e-13 49.0 1.7 1.1 1 0 0 1 1 1 1 DASH complex subunit Dad4 DASH_Dad1 PF08649.10 CBK23636.2 - 0.00061 19.9 0.3 0.00068 19.8 0.3 1.1 1 0 0 1 1 1 1 DASH complex subunit Dad1 BLOC1_2 PF10046.9 CBK23636.2 - 0.038 14.3 1.6 0.048 14.0 1.6 1.1 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 BORCS7 PF16088.5 CBK23636.2 - 0.051 13.8 0.2 0.067 13.4 0.2 1.1 1 0 0 1 1 1 0 BLOC-1-related complex sub-unit 7 DASH_Dam1 PF08653.10 CBK23636.2 - 0.1 12.4 0.1 0.14 12.0 0.1 1.2 1 0 0 1 1 1 0 DASH complex subunit Dam1 AAA PF00004.29 CBK23637.2 - 2.3e-32 112.2 0.0 4.6e-32 111.2 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 CBK23637.2 - 2.3e-06 27.4 0.0 6.6e-05 22.7 0.0 2.2 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 CBK23637.2 - 0.00012 22.5 0.1 0.00092 19.6 0.1 2.3 1 1 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.14 CBK23637.2 - 0.00019 21.5 0.7 0.017 15.1 0.3 3.6 3 1 0 3 3 3 1 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 CBK23637.2 - 0.00038 21.0 0.0 0.0015 19.1 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 CBK23637.2 - 0.00073 19.7 0.0 0.0018 18.4 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_2 PF07724.14 CBK23637.2 - 0.00079 19.6 0.1 0.0065 16.6 0.1 2.2 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 CBK23637.2 - 0.00082 19.7 0.9 1.4 9.2 0.0 2.8 1 1 2 3 3 3 2 AAA domain AAA_14 PF13173.6 CBK23637.2 - 0.0033 17.4 0.0 0.01 15.9 0.0 1.8 2 0 0 2 2 1 1 AAA domain AAA_11 PF13086.6 CBK23637.2 - 0.011 15.5 0.0 0.045 13.5 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA_lid_3 PF17862.1 CBK23637.2 - 0.024 14.4 0.0 0.077 12.8 0.0 1.8 1 0 0 1 1 1 0 AAA+ lid domain TIP49 PF06068.13 CBK23637.2 - 0.025 13.8 0.0 0.048 12.9 0.0 1.4 1 0 0 1 1 1 0 TIP49 P-loop domain TsaE PF02367.17 CBK23637.2 - 0.03 14.3 0.0 0.052 13.5 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Sigma54_activat PF00158.26 CBK23637.2 - 0.04 13.6 0.0 0.78 9.4 0.0 2.6 3 0 0 3 3 3 0 Sigma-54 interaction domain Zeta_toxin PF06414.12 CBK23637.2 - 0.042 13.1 0.0 0.076 12.3 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin NACHT PF05729.12 CBK23637.2 - 0.075 12.9 0.2 5.5 6.9 0.0 3.1 3 0 0 3 3 3 0 NACHT domain GerE PF00196.19 CBK23637.2 - 0.079 12.5 0.2 0.18 11.4 0.2 1.6 1 0 0 1 1 1 0 Bacterial regulatory proteins, luxR family Mg_chelatase PF01078.21 CBK23637.2 - 0.12 11.8 0.0 0.45 9.8 0.0 1.9 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_28 PF13521.6 CBK23637.2 - 0.14 12.4 0.0 0.47 10.7 0.0 2.0 1 1 0 1 1 1 0 AAA domain Gar1 PF04410.14 CBK23638.2 - 1.7e-05 24.7 0.0 1.9e-05 24.5 0.0 1.0 1 0 0 1 1 1 1 Gar1/Naf1 RNA binding region AAA_12 PF13087.6 CBK23639.2 - 5.4e-53 179.6 0.0 6.8e-53 179.3 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 CBK23639.2 - 1.9e-25 90.2 0.0 2.6e-25 89.7 0.0 1.2 1 0 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 CBK23639.2 - 0.0001 22.2 0.2 0.016 14.9 0.0 2.2 1 1 1 2 2 2 2 Viral (Superfamily 1) RNA helicase PRTase_1 PF11202.8 CBK23639.2 - 0.074 12.3 0.0 0.14 11.4 0.0 1.4 1 0 0 1 1 1 0 Phosphoribosyl transferase (PRTase) AAA_30 PF13604.6 CBK23639.2 - 0.11 12.2 0.0 0.16 11.6 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 CBK23639.2 - 0.18 12.1 0.0 0.42 10.9 0.0 1.5 2 0 0 2 2 2 0 AAA domain zf-CCCH PF00642.24 CBK23640.2 - 1.9e-12 46.8 15.8 1e-06 28.5 3.8 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RRM_1 PF00076.22 CBK23640.2 - 2.8e-07 30.3 0.0 4.8e-07 29.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf_CCCH_4 PF18345.1 CBK23640.2 - 9.9e-05 22.3 15.2 0.0081 16.2 2.5 2.4 2 0 0 2 2 2 2 Zinc finger domain zf-CCCH_3 PF15663.5 CBK23640.2 - 0.0053 17.0 1.5 1.6 9.0 0.2 2.3 2 0 0 2 2 2 2 Zinc-finger containing family Nup35_RRM_2 PF14605.6 CBK23640.2 - 0.045 13.8 0.0 0.1 12.6 0.0 1.6 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Torus PF16131.5 CBK23640.2 - 0.32 11.7 0.3 0.32 11.7 0.3 3.9 3 2 1 4 4 4 0 Torus domain zf-CCCH_4 PF18044.1 CBK23640.2 - 4.6 7.1 17.3 0.38 10.6 5.1 2.6 2 0 0 2 2 2 0 CCCH-type zinc finger Scramblase PF03803.15 CBK23642.2 - 1.5e-08 34.2 0.0 2.2e-08 33.7 0.0 1.2 1 0 0 1 1 1 1 Scramblase PEPCK_ATP PF01293.20 CBK23646.2 - 0.00077 18.2 0.0 0.01 14.6 0.0 2.0 2 0 0 2 2 2 2 Phosphoenolpyruvate carboxykinase UCH PF00443.29 CBK23647.2 - 5.3e-37 127.7 0.0 7e-37 127.3 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.12 CBK23647.2 - 1.5e-09 38.4 0.2 4.8e-09 36.7 0.0 2.0 2 0 0 2 2 2 1 DUSP domain UCH_1 PF13423.6 CBK23647.2 - 6.5e-07 29.2 0.8 1.8e-05 24.5 0.7 2.1 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Ubiquitin_3 PF14836.6 CBK23647.2 - 9e-07 28.8 0.4 1.8e-06 27.8 0.4 1.4 1 0 0 1 1 1 1 Ubiquitin-like domain Ubiquitin_2 PF14560.6 CBK23647.2 - 0.00084 19.8 0.1 0.0018 18.7 0.1 1.5 1 0 0 1 1 1 1 Ubiquitin-like domain ubiquitin PF00240.23 CBK23647.2 - 0.15 11.8 0.3 0.54 10.1 0.3 1.9 1 1 0 1 1 1 0 Ubiquitin family Alpha_E2_glycop PF00943.19 CBK23648.2 - 0.086 11.6 0.3 0.14 10.8 0.3 1.3 1 0 0 1 1 1 0 Alphavirus E2 glycoprotein WD40 PF00400.32 CBK23649.2 - 3.1e-58 192.4 22.8 3e-09 37.4 0.2 8.9 8 1 0 8 8 8 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBK23649.2 - 7.1e-21 74.3 1.2 0.00028 21.1 0.1 5.7 2 2 3 5 5 5 5 Anaphase-promoting complex subunit 4 WD40 domain NLE PF08154.12 CBK23649.2 - 1.1e-14 54.7 0.6 2.1e-14 53.8 0.6 1.5 1 0 0 1 1 1 1 NLE (NUC135) domain Ge1_WD40 PF16529.5 CBK23649.2 - 4.5e-09 35.7 0.0 0.033 13.1 0.0 4.3 3 1 2 5 5 5 2 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 CBK23649.2 - 4.2e-08 33.3 0.0 0.00054 19.9 0.0 3.4 3 1 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 CBK23649.2 - 1.1e-06 27.6 2.1 0.65 8.6 0.0 4.7 3 2 1 5 5 5 3 Nucleoporin Nup120/160 PD40 PF07676.12 CBK23649.2 - 0.0003 20.7 3.4 12 6.0 0.1 4.6 4 0 0 4 4 4 1 WD40-like Beta Propeller Repeat Proteasome_A_N PF10584.9 CBK23649.2 - 0.0024 17.5 0.4 3.7 7.3 0.0 3.7 3 0 0 3 3 3 1 Proteasome subunit A N-terminal signature Nbas_N PF15492.6 CBK23649.2 - 0.003 17.0 0.1 0.63 9.3 0.0 3.6 2 2 2 4 4 4 1 Neuroblastoma-amplified sequence, N terminal WD40_like PF17005.5 CBK23649.2 - 0.034 13.5 0.0 11 5.2 0.0 3.4 4 0 0 4 4 4 0 WD40-like domain Cytochrom_D1 PF02239.16 CBK23649.2 - 0.058 11.9 0.0 0.62 8.5 0.0 2.2 1 1 1 2 2 2 0 Cytochrome D1 heme domain Nucleoporin_N PF08801.11 CBK23649.2 - 0.085 11.6 0.0 0.63 8.7 0.0 2.1 2 0 0 2 2 2 0 Nup133 N terminal like IKI3 PF04762.12 CBK23649.2 - 0.22 9.4 0.1 2.7 5.9 0.0 2.2 2 0 0 2 2 2 0 IKI3 family Histone_H2A_C PF16211.5 CBK23650.2 - 3.1e-15 55.6 0.0 5e-15 54.9 0.0 1.4 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 CBK23650.2 - 3.8e-13 50.0 0.2 6e-13 49.3 0.0 1.4 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 CBK23650.2 - 1.4e-05 25.3 0.0 1.9e-05 24.8 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 CBK23651.2 - 2.6e-20 73.1 0.3 3.6e-20 72.6 0.3 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 CBK23651.2 - 2e-05 24.8 0.0 4e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone NMT PF01233.19 CBK23652.2 - 8.2e-67 224.0 0.0 1.2e-66 223.5 0.0 1.3 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain NMT_C PF02799.15 CBK23652.2 - 1.9e-62 210.5 0.2 4.7e-62 209.2 0.1 1.6 2 0 0 2 2 2 1 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain Acetyltransf_9 PF13527.7 CBK23652.2 - 1.1e-05 25.5 0.0 0.00025 21.1 0.0 2.2 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 CBK23652.2 - 0.036 14.3 0.0 0.1 12.8 0.0 1.8 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Snf7 PF03357.21 CBK23653.2 - 1.7e-06 27.8 2.6 1.7e-06 27.8 2.6 2.1 1 1 1 2 2 2 1 Snf7 Baculo_PEP_C PF04513.12 CBK23653.2 - 0.0091 16.0 0.1 0.33 11.0 0.0 2.5 2 1 0 2 2 2 1 Baculovirus polyhedron envelope protein, PEP, C terminus Prominin PF05478.11 CBK23653.2 - 0.014 13.4 7.5 0.47 8.4 0.6 2.1 1 1 1 2 2 2 0 Prominin Snapin_Pallidin PF14712.6 CBK23653.2 - 0.034 14.6 4.8 16 6.0 0.1 3.5 2 1 1 3 3 3 0 Snapin/Pallidin GlcNAc-1_reg PF18440.1 CBK23653.2 - 0.035 14.3 0.1 0.12 12.6 0.1 1.9 1 0 0 1 1 1 0 Putative GlcNAc-1 phosphotransferase regulatory domain KxDL PF10241.9 CBK23653.2 - 0.15 12.4 6.6 0.14 12.5 0.7 3.0 3 0 0 3 3 3 0 Uncharacterized conserved protein Carbpep_Y_N PF05388.11 CBK23653.2 - 0.21 12.1 1.9 2.6 8.6 0.1 2.5 2 1 0 2 2 2 0 Carboxypeptidase Y pro-peptide DUF5618 PF18498.1 CBK23653.2 - 0.37 11.0 3.4 12 6.1 0.2 3.4 3 1 0 3 3 3 0 Domain of unknown function (DUF5618) NPV_P10 PF05531.12 CBK23653.2 - 0.57 10.7 2.6 3.1 8.3 0.1 3.2 2 2 1 3 3 3 0 Nucleopolyhedrovirus P10 protein Exonuc_VII_L PF02601.15 CBK23653.2 - 0.71 9.4 4.6 1.3 8.6 4.6 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit RecG_N PF17190.4 CBK23653.2 - 1.2 9.9 6.3 9.9 7.0 0.6 3.4 2 1 1 3 3 3 0 RecG N-terminal helical domain Tweety PF04906.13 CBK23653.2 - 2.7 6.6 5.6 1.8 7.2 1.2 2.1 1 1 0 2 2 2 0 Tweety Metallophos PF00149.28 CBK23654.2 - 1e-28 101.3 0.0 1.3e-28 100.9 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Mpp10 PF04006.12 CBK23655.2 - 1.4e-09 37.0 0.0 1.7e-09 36.8 0.0 1.0 1 0 0 1 1 1 1 Mpp10 protein Rad51 PF08423.11 CBK23656.2 - 2.4e-118 394.0 0.1 2.9e-118 393.7 0.1 1.1 1 0 0 1 1 1 1 Rad51 RecA PF00154.21 CBK23656.2 - 3.5e-12 46.4 0.0 4.9e-12 45.9 0.0 1.1 1 0 0 1 1 1 1 recA bacterial DNA recombination protein AAA_25 PF13481.6 CBK23656.2 - 1.5e-08 34.5 0.0 2.2e-08 33.9 0.0 1.2 1 0 0 1 1 1 1 AAA domain ATPase PF06745.13 CBK23656.2 - 9e-08 31.7 0.0 1.5e-07 31.1 0.0 1.5 1 1 0 1 1 1 1 KaiC HHH_5 PF14520.6 CBK23656.2 - 1.8e-06 28.4 0.1 3.7e-06 27.5 0.1 1.5 1 0 0 1 1 1 1 Helix-hairpin-helix domain AAA_24 PF13479.6 CBK23656.2 - 2.4e-05 24.1 0.0 8.9e-05 22.3 0.0 1.8 2 0 0 2 2 2 1 AAA domain DnaB_C PF03796.15 CBK23656.2 - 0.00026 20.4 0.0 0.012 15.0 0.0 2.3 2 0 0 2 2 2 1 DnaB-like helicase C terminal domain PAXNEB PF05625.11 CBK23656.2 - 0.00091 18.5 0.0 0.01 15.0 0.0 2.1 2 0 0 2 2 2 1 PAXNEB protein AAA PF00004.29 CBK23656.2 - 0.0083 16.5 0.0 0.14 12.6 0.0 2.4 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 CBK23656.2 - 0.013 15.8 0.2 0.13 12.4 0.1 2.1 2 0 0 2 2 2 0 AAA domain GvpD PF07088.11 CBK23656.2 - 0.017 13.8 0.0 0.027 13.1 0.0 1.3 1 0 0 1 1 1 0 GvpD gas vesicle protein DUF3853 PF12964.7 CBK23656.2 - 0.043 14.0 0.1 2.8 8.1 0.0 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF3853) ubiquitin PF00240.23 CBK23657.2 - 1.7e-07 30.9 0.2 8.1e-07 28.7 0.2 1.8 1 1 0 1 1 1 1 Ubiquitin family Ubiquitin_2 PF14560.6 CBK23657.2 - 2.7e-05 24.5 0.1 0.00016 22.1 0.1 1.9 1 1 0 1 1 1 1 Ubiquitin-like domain Rad60-SLD PF11976.8 CBK23657.2 - 0.057 13.2 0.1 0.29 11.0 0.1 1.9 1 1 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_4 PF18036.1 CBK23657.2 - 0.063 13.3 0.1 0.47 10.5 0.0 1.9 1 1 1 2 2 2 0 Ubiquitin-like domain Peptidase_S49_N PF08496.10 CBK23659.2 - 0.84 9.7 4.2 0.87 9.6 4.2 1.1 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Med19 PF10278.9 CBK23659.2 - 2.5 8.0 9.8 2.4 8.0 9.8 1.1 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 DnaJ PF00226.31 CBK23660.2 - 6e-20 71.1 0.6 1.6e-19 69.8 0.6 1.8 1 0 0 1 1 1 1 DnaJ domain FancD2 PF14631.6 CBK23660.2 - 0.05 11.0 0.2 0.063 10.7 0.2 1.1 1 0 0 1 1 1 0 Fanconi anaemia protein FancD2 nuclease JAB PF01398.21 CBK23661.2 - 8.5e-11 41.9 0.0 1.6e-10 41.0 0.0 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Ost5 PF05251.12 CBK23662.2 - 3.6e-16 59.2 6.3 3.9e-16 59.1 6.3 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase subunit 5 DUF2157 PF09925.9 CBK23662.2 - 0.043 13.6 3.6 0.055 13.3 3.6 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2157) Pkinase PF00069.25 CBK23664.2 - 9e-66 221.9 0.0 1.3e-65 221.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBK23664.2 - 3.1e-49 167.6 0.0 4.2e-49 167.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CBK23664.2 - 8e-06 24.9 0.0 2.1e-05 23.5 0.0 1.6 2 0 0 2 2 2 1 Fungal protein kinase Haspin_kinase PF12330.8 CBK23664.2 - 0.0013 17.7 0.0 0.089 11.7 0.0 2.2 1 1 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 CBK23664.2 - 0.021 14.1 0.0 0.069 12.5 0.0 1.8 1 1 0 1 1 1 0 Kinase-like Kdo PF06293.14 CBK23664.2 - 0.06 12.7 0.0 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Alpha_E2_glycop PF00943.19 CBK23665.2 - 0.076 11.7 0.3 0.13 11.0 0.3 1.3 1 0 0 1 1 1 0 Alphavirus E2 glycoprotein NLE PF08154.12 CBK23666.2 - 3e-16 59.7 0.2 4.2e-16 59.2 0.2 1.2 1 0 0 1 1 1 1 NLE (NUC135) domain Memo PF01875.17 CBK23667.2 - 2.2e-38 131.9 0.0 2.5e-38 131.8 0.0 1.0 1 0 0 1 1 1 1 Memo-like protein Gtr1_RagA PF04670.12 CBK23668.2 - 1.6e-25 89.8 0.4 1.9e-25 89.6 0.4 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region DUF1992 PF09350.10 CBK23668.2 - 0.059 13.5 0.0 0.089 13.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1992) RF-1 PF00472.20 CBK23669.2 - 3.6e-37 126.9 0.5 5.2e-37 126.3 0.5 1.2 1 0 0 1 1 1 1 RF-1 domain PCRF PF03462.18 CBK23669.2 - 9.8e-24 84.3 0.1 2e-21 76.7 0.0 2.1 2 0 0 2 2 2 2 PCRF domain SH3_2 PF07653.17 CBK23670.2 - 1.2e-06 28.1 0.0 1.2e-06 28.0 0.0 1.1 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 CBK23670.2 - 1.9e-06 27.4 0.0 2.2e-06 27.2 0.0 1.1 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 CBK23670.2 - 1.9e-05 24.4 0.0 1.9e-05 24.4 0.0 1.1 1 0 0 1 1 1 1 Variant SH3 domain FAA_hydrolase PF01557.18 CBK23671.2 - 1.8e-58 197.8 0.0 2e-58 197.6 0.0 1.0 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family Ribosomal_S17 PF00366.20 CBK23672.2 - 1.8e-18 66.4 6.7 2.7e-18 65.8 6.7 1.3 1 0 0 1 1 1 1 Ribosomal protein S17 PMSI1 PF15322.6 CBK23672.2 - 0.025 14.1 0.1 0.029 13.8 0.1 1.3 1 1 0 1 1 1 0 Protein missing in infertile sperm 1, putative DUF778 PF05608.12 CBK23673.2 - 8.5e-10 39.3 1.5 0.00026 21.4 0.0 2.8 1 1 1 2 2 2 2 Protein of unknown function (DUF778) zf-CCHC PF00098.23 CBK23674.2 - 1.1e-12 47.4 35.2 0.00013 21.8 3.5 5.5 6 0 0 6 6 6 3 Zinc knuckle zf-CCHC_3 PF13917.6 CBK23674.2 - 7.4e-08 32.2 27.9 0.00088 19.2 0.7 4.5 2 1 2 4 4 4 4 Zinc knuckle zf-CCHC_2 PF13696.6 CBK23674.2 - 0.016 15.0 1.8 0.016 15.0 1.8 5.7 7 0 0 7 7 7 0 Zinc knuckle zf-CCHC_4 PF14392.6 CBK23674.2 - 1.1 9.0 34.6 0.58 9.9 3.3 4.9 5 0 0 5 5 5 0 Zinc knuckle zf-CCHC_6 PF15288.6 CBK23674.2 - 7.6 6.5 24.6 7.1 6.6 2.6 4.7 4 0 0 4 4 4 0 Zinc knuckle Myb_DNA-bind_7 PF15963.5 CBK23675.2 - 4.9e-13 48.8 1.4 8.7e-13 48.0 0.1 2.0 2 0 0 2 2 2 1 Myb DNA-binding like Myb_DNA-binding PF00249.31 CBK23675.2 - 0.00024 21.2 0.0 0.00077 19.6 0.0 1.9 2 0 0 2 2 2 1 Myb-like DNA-binding domain PAPS_reduct PF01507.19 CBK23676.2 - 3.5e-22 79.3 0.0 9.6e-21 74.6 0.0 2.1 1 1 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family Med25 PF11232.8 CBK23676.2 - 0.11 12.5 0.0 0.15 12.0 0.0 1.2 1 0 0 1 1 1 0 Mediator complex subunit 25 PTOV activation and synapsin 2 AAA_2 PF07724.14 CBK23677.2 - 1.5e-51 174.9 0.0 5.5e-50 169.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_lid_9 PF17871.1 CBK23677.2 - 1.2e-28 99.1 0.5 2.1e-28 98.3 0.5 1.4 1 0 0 1 1 1 1 AAA lid domain ClpB_D2-small PF10431.9 CBK23677.2 - 7.8e-24 83.5 0.0 2e-23 82.3 0.0 1.8 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA PF00004.29 CBK23677.2 - 8.3e-23 81.3 0.0 2.2e-12 47.6 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 CBK23677.2 - 2.4e-15 56.8 0.0 1.5e-10 41.2 0.0 2.9 3 0 0 3 3 2 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 CBK23677.2 - 1.8e-12 47.9 0.8 1.7e-05 25.3 0.1 4.4 4 1 0 4 4 3 2 AAA ATPase domain Sigma54_activat PF00158.26 CBK23677.2 - 6.5e-08 32.5 0.0 9.3e-05 22.2 0.0 2.7 2 1 0 2 2 2 2 Sigma-54 interaction domain AAA_22 PF13401.6 CBK23677.2 - 1.3e-07 32.0 2.9 0.032 14.5 0.0 4.6 3 2 0 3 3 3 2 AAA domain AAA_7 PF12775.7 CBK23677.2 - 5.5e-07 29.3 0.0 0.0089 15.6 0.0 2.5 2 0 0 2 2 2 2 P-loop containing dynein motor region TniB PF05621.11 CBK23677.2 - 1.5e-06 27.8 0.0 0.0052 16.2 0.0 3.5 2 1 0 2 2 2 1 Bacterial TniB protein ATPase_2 PF01637.18 CBK23677.2 - 3.9e-06 27.0 0.4 0.88 9.4 0.1 4.0 5 0 0 5 5 3 2 ATPase domain predominantly from Archaea RuvB_N PF05496.12 CBK23677.2 - 2.6e-05 24.0 0.3 0.35 10.6 0.0 3.6 2 1 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain RNA_helicase PF00910.22 CBK23677.2 - 0.00018 21.9 0.0 0.17 12.3 0.0 2.8 3 0 0 3 3 2 1 RNA helicase IstB_IS21 PF01695.17 CBK23677.2 - 0.00024 20.9 0.0 0.35 10.6 0.0 2.5 2 0 0 2 2 2 2 IstB-like ATP binding protein Roc PF08477.13 CBK23677.2 - 0.00028 21.1 0.0 0.74 10.0 0.0 2.4 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase AAA_18 PF13238.6 CBK23677.2 - 0.00037 21.0 0.1 0.9 10.1 0.0 3.0 3 0 0 3 3 2 1 AAA domain TsaE PF02367.17 CBK23677.2 - 0.00039 20.4 0.0 0.56 10.2 0.0 2.4 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_24 PF13479.6 CBK23677.2 - 0.00045 20.0 0.0 1.1 8.9 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_14 PF13173.6 CBK23677.2 - 0.00051 20.1 0.0 1.1 9.3 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_3 PF07726.11 CBK23677.2 - 0.00059 19.7 0.0 0.11 12.3 0.0 3.0 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.6 CBK23677.2 - 0.00086 19.7 0.1 0.53 10.6 0.1 3.5 3 1 0 3 3 3 1 AAA domain Mg_chelatase PF01078.21 CBK23677.2 - 0.00092 18.6 0.0 1.9 7.8 0.0 2.9 3 0 0 3 3 3 2 Magnesium chelatase, subunit ChlI NACHT PF05729.12 CBK23677.2 - 0.002 18.1 0.0 0.18 11.7 0.0 2.5 2 0 0 2 2 2 1 NACHT domain MCM PF00493.23 CBK23677.2 - 0.0067 15.6 0.0 1.2 8.1 0.0 2.7 2 1 0 2 2 2 1 MCM P-loop domain ABC_tran PF00005.27 CBK23677.2 - 0.0073 16.8 0.0 2.3 8.8 0.0 2.7 2 0 0 2 2 2 1 ABC transporter AAA_29 PF13555.6 CBK23677.2 - 0.012 15.3 0.0 5.9 6.7 0.0 2.9 3 0 0 3 3 3 0 P-loop containing region of AAA domain NTPase_1 PF03266.15 CBK23677.2 - 0.013 15.4 0.1 6.8 6.6 0.0 2.8 2 0 0 2 2 2 0 NTPase DNA_pol3_delta2 PF13177.6 CBK23677.2 - 0.02 14.7 0.0 9.2 6.0 0.0 2.7 2 0 0 2 2 2 0 DNA polymerase III, delta subunit RsgA_GTPase PF03193.16 CBK23677.2 - 0.02 14.8 0.0 6.2 6.7 0.0 2.4 2 0 0 2 2 2 0 RsgA GTPase RHH_3 PF12651.7 CBK23677.2 - 0.026 14.5 0.0 0.65 10.0 0.0 3.1 3 0 0 3 3 3 0 Ribbon-helix-helix domain AAA_25 PF13481.6 CBK23677.2 - 0.028 14.0 0.0 1.5 8.4 0.0 3.1 3 0 0 3 3 3 0 AAA domain ResIII PF04851.15 CBK23677.2 - 0.038 14.0 0.0 3.1 7.8 0.0 3.4 3 1 1 4 4 4 0 Type III restriction enzyme, res subunit AAA_23 PF13476.6 CBK23677.2 - 0.044 14.3 0.0 6.2 7.3 0.0 2.4 2 0 0 2 2 2 0 AAA domain ATP_bind_1 PF03029.17 CBK23677.2 - 0.056 13.2 0.1 5.6 6.7 0.0 2.6 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_33 PF13671.6 CBK23677.2 - 0.082 13.1 0.2 7.9 6.6 0.0 2.7 3 0 0 3 3 2 0 AAA domain AAA_28 PF13521.6 CBK23677.2 - 0.085 13.1 0.1 49 4.1 0.0 3.5 4 0 0 4 4 3 0 AAA domain Cyclin_N PF00134.23 CBK23677.2 - 0.15 11.8 0.0 0.33 10.7 0.0 1.5 1 0 0 1 1 1 0 Cyclin, N-terminal domain MMR_HSR1 PF01926.23 CBK23677.2 - 0.15 12.1 0.0 29 4.8 0.0 2.9 2 0 0 2 2 2 0 50S ribosome-binding GTPase DUF87 PF01935.17 CBK23677.2 - 0.16 12.1 0.1 15 5.5 0.0 2.6 3 0 0 3 3 2 0 Helicase HerA, central domain GDPD PF03009.17 CBK23678.2 - 4.4e-41 141.3 0.0 9.3e-41 140.3 0.0 1.5 2 0 0 2 2 2 1 Glycerophosphoryl diester phosphodiesterase family La_HTH_kDCL PF18177.1 CBK23678.2 - 0.11 12.8 0.0 0.27 11.6 0.0 1.6 1 0 0 1 1 1 0 La HTH in kinetoplastid DICER domain Bromodomain PF00439.25 CBK23679.2 - 1.5e-10 41.0 0.2 2.8e-10 40.1 0.1 1.5 1 1 0 1 1 1 1 Bromodomain SprT-like PF10263.9 CBK23680.2 - 2.9e-19 69.0 0.8 5.2e-19 68.2 0.8 1.4 1 0 0 1 1 1 1 SprT-like family Saf_2TM PF18303.1 CBK23680.2 - 0.037 13.6 0.2 0.077 12.6 0.2 1.7 1 0 0 1 1 1 0 SAVED-fused 2TM effector domain DUF2367 PF10164.9 CBK23680.2 - 0.038 14.5 0.0 0.07 13.6 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2367) DUF2207 PF09972.9 CBK23680.2 - 0.061 12.1 0.7 1.3 7.7 0.2 2.0 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) ASFV_J13L PF05568.11 CBK23680.2 - 0.091 12.5 0.8 0.14 11.9 0.8 1.2 1 0 0 1 1 1 0 African swine fever virus J13L protein Peptidase_M91 PF14891.6 CBK23680.2 - 0.12 12.7 0.1 0.17 12.2 0.1 1.2 1 0 0 1 1 1 0 Effector protein Ribosomal_L20 PF00453.18 CBK23680.2 - 0.13 12.3 0.4 0.32 11.1 0.1 1.8 2 0 0 2 2 2 0 Ribosomal protein L20 DUF4834 PF16118.5 CBK23680.2 - 0.17 12.9 1.4 0.26 12.3 0.6 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) WLM PF08325.10 CBK23680.2 - 0.22 11.6 1.5 0.49 10.4 1.6 1.4 1 1 0 1 1 1 0 WLM domain Vpu PF00558.19 CBK23680.2 - 0.63 9.9 2.9 0.74 9.6 1.5 1.8 2 0 0 2 2 2 0 Vpu protein DEAD PF00270.29 CBK23681.2 - 1.3e-42 145.6 0.0 1.9e-42 145.0 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CBK23681.2 - 1.9e-28 99.0 0.1 3.6e-28 98.1 0.1 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 CBK23681.2 - 0.00013 22.0 0.0 0.0003 20.8 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Phage_integrase PF00589.22 CBK23681.2 - 0.13 12.1 0.1 0.3 10.9 0.1 1.8 1 1 0 1 1 1 0 Phage integrase family DUF3549 PF12069.8 CBK23681.2 - 0.14 11.2 0.1 1 8.3 0.1 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3549) Bax1-I PF01027.20 CBK23682.2 - 2.2e-19 70.1 25.3 2.5e-19 69.9 25.3 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 Pkinase PF00069.25 CBK23684.2 - 1.9e-59 201.2 0.1 1.2e-58 198.6 0.1 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBK23684.2 - 1.8e-31 109.3 1.3 7.4e-23 81.1 0.3 2.2 1 1 1 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 CBK23684.2 - 0.00095 18.6 1.4 0.025 13.9 0.1 2.8 2 1 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 CBK23684.2 - 0.0016 17.4 0.9 0.0023 16.9 0.9 1.2 1 0 0 1 1 1 1 Haspin like kinase domain DUF148 PF02520.17 CBK23684.2 - 0.018 15.2 1.2 0.036 14.2 1.2 1.5 1 0 0 1 1 1 0 Domain of unknown function DUF148 Aminotran_1_2 PF00155.21 CBK23685.2 - 7e-48 163.6 0.0 8.3e-48 163.4 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 CBK23685.2 - 0.014 14.7 0.0 0.03 13.6 0.0 1.6 1 0 0 1 1 1 0 Beta-eliminating lyase Ldh_1_N PF00056.23 CBK23685.2 - 0.075 13.1 0.0 2.9 8.0 0.0 2.2 2 0 0 2 2 2 0 lactate/malate dehydrogenase, NAD binding domain Aminotran_MocR PF12897.7 CBK23685.2 - 0.09 11.5 0.0 0.11 11.2 0.0 1.2 1 0 0 1 1 1 0 Alanine-glyoxylate amino-transferase Glyco_hydro_8 PF01270.17 CBK23685.2 - 0.1 11.4 0.0 1.1 8.0 0.0 2.2 2 0 0 2 2 2 0 Glycosyl hydrolases family 8 Ribosomal_L30 PF00327.20 CBK23686.2 - 7.8e-21 73.7 1.8 1.8e-20 72.5 1.8 1.7 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e Mon1 PF03164.14 CBK23687.2 - 6.2e-58 196.8 1.8 1.5e-57 195.5 1.8 1.5 1 1 0 1 1 1 1 Trafficking protein Mon1 Ribosomal_S7e PF01251.18 CBK23688.2 - 7.5e-65 218.1 0.7 8.9e-65 217.9 0.7 1.0 1 0 0 1 1 1 1 Ribosomal protein S7e Calpain_u2 PF16648.5 CBK23688.2 - 0.057 13.9 0.1 8.7 6.9 0.0 2.6 2 0 0 2 2 2 0 Unstructured region on Calpain-3 SPC22 PF04573.12 CBK23689.2 - 2.6e-14 53.1 0.1 5.2e-14 52.1 0.1 1.4 1 1 0 1 1 1 1 Signal peptidase subunit TPR_1 PF00515.28 CBK23690.2 - 1.3e-15 56.5 7.0 0.0037 17.0 0.1 5.6 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_2 PF07719.17 CBK23690.2 - 6.7e-15 53.9 13.3 0.015 15.4 0.2 6.1 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_16 PF13432.6 CBK23690.2 - 1.1e-13 51.6 11.8 2e-07 31.5 0.2 5.2 3 1 2 5 5 5 4 Tetratricopeptide repeat TPR_8 PF13181.6 CBK23690.2 - 7.4e-11 41.4 1.1 0.76 10.1 0.1 6.4 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_17 PF13431.6 CBK23690.2 - 1.2e-10 41.0 3.1 0.011 16.1 0.0 4.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.6 CBK23690.2 - 2.2e-09 36.8 8.9 0.00081 19.0 0.0 5.1 4 1 1 5 5 5 3 TPR repeat TPR_19 PF14559.6 CBK23690.2 - 8.8e-09 35.8 12.4 1.1e-05 25.9 0.1 4.8 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_14 PF13428.6 CBK23690.2 - 8.9e-09 35.5 11.4 0.0086 16.8 0.1 6.1 4 1 2 6 6 6 3 Tetratricopeptide repeat TPR_12 PF13424.6 CBK23690.2 - 2.9e-07 30.7 18.7 0.03 14.6 0.9 4.8 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_6 PF13174.6 CBK23690.2 - 4.2e-06 27.1 8.9 4.9 8.0 0.0 6.0 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_7 PF13176.6 CBK23690.2 - 8.8e-05 22.3 11.3 1.1 9.5 0.1 6.1 6 1 0 6 6 6 2 Tetratricopeptide repeat TPR_9 PF13371.6 CBK23690.2 - 0.00028 21.0 17.1 0.036 14.2 3.2 4.8 2 1 3 5 5 5 2 Tetratricopeptide repeat TPR_20 PF14561.6 CBK23690.2 - 0.0041 17.4 3.1 26 5.2 0.0 4.0 3 1 2 5 5 5 0 Tetratricopeptide repeat TPR_3 PF07720.12 CBK23690.2 - 0.013 15.4 4.9 0.68 10.0 0.3 3.9 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_15 PF13429.6 CBK23690.2 - 0.016 14.4 0.7 8.8 5.4 0.0 3.1 1 1 2 3 3 3 0 Tetratricopeptide repeat Type_III_YscG PF09477.10 CBK23690.2 - 0.044 13.8 0.1 19 5.4 0.0 2.9 2 1 1 3 3 3 0 Bacterial type II secretion system chaperone protein (type_III_yscG) Alkyl_sulf_dimr PF14863.6 CBK23690.2 - 0.062 13.8 0.2 0.3 11.6 0.0 2.2 2 1 0 2 2 2 0 Alkyl sulfatase dimerisation TPR_4 PF07721.14 CBK23690.2 - 2.1 9.2 13.8 9.2 7.2 1.1 5.2 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_10 PF13374.6 CBK23690.2 - 9.6 6.2 13.6 46 4.1 0.2 5.2 5 0 0 5 5 5 0 Tetratricopeptide repeat PI3_PI4_kinase PF00454.27 CBK23691.2 - 1.7e-24 87.0 0.0 2.7e-24 86.4 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase ubiquitin PF00240.23 CBK23691.2 - 0.013 15.3 0.0 0.027 14.2 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin family COPI_assoc PF08507.10 CBK23692.2 - 6.5e-12 45.6 15.0 8.2e-12 45.3 15.0 1.1 1 0 0 1 1 1 1 COPI associated protein NPCC PF08058.11 CBK23692.2 - 3.1 7.8 9.6 0.98 9.5 6.4 1.9 1 1 1 2 2 2 0 Nuclear pore complex component MORN PF02493.20 CBK23693.2 - 7.5e-07 28.7 16.7 0.00012 21.7 0.2 3.6 4 0 0 4 4 4 2 MORN repeat HAD_2 PF13419.6 CBK23694.2 - 3.4e-10 40.3 0.1 7.8e-10 39.1 0.0 1.6 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 CBK23694.2 - 4.9e-06 27.0 0.0 6.5e-06 26.6 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 CBK23694.2 - 0.016 15.3 0.0 0.034 14.3 0.0 1.5 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase TPR_1 PF00515.28 CBK23695.2 - 1.2e-17 62.9 4.1 7.6e-06 25.5 0.1 3.1 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 CBK23695.2 - 1.5e-16 59.1 3.3 0.00014 21.7 0.3 3.1 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.6 CBK23695.2 - 1.2e-10 40.7 2.3 0.023 14.9 0.2 3.3 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 CBK23695.2 - 5.2e-08 32.4 6.5 1.5e-05 24.6 0.6 3.0 1 1 2 3 3 3 2 TPR repeat TPR_7 PF13176.6 CBK23695.2 - 6.9e-08 32.0 0.0 0.0057 16.6 0.0 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.6 CBK23695.2 - 2.6e-06 27.6 1.7 0.12 12.7 0.4 3.0 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.6 CBK23695.2 - 3.1e-06 27.2 0.8 0.0049 17.2 0.0 2.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 CBK23695.2 - 1.3e-05 25.6 0.0 0.018 15.6 0.0 2.1 1 1 1 2 2 2 2 Tetratricopeptide repeat MIT PF04212.18 CBK23695.2 - 3.8e-05 23.7 1.8 0.023 14.7 0.1 3.0 3 1 0 3 3 3 2 MIT (microtubule interacting and transport) domain SHNi-TPR PF10516.9 CBK23695.2 - 9e-05 21.8 0.3 3.4 7.2 0.1 3.3 3 0 0 3 3 3 1 SHNi-TPR TPR_14 PF13428.6 CBK23695.2 - 0.00047 20.7 0.0 14 6.8 0.0 3.1 1 1 2 3 3 3 0 Tetratricopeptide repeat ANAPC3 PF12895.7 CBK23695.2 - 0.00064 19.9 2.2 0.0012 19.1 2.2 1.5 1 1 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 BTAD PF03704.17 CBK23695.2 - 0.0038 17.7 0.1 0.27 11.6 0.0 2.0 1 1 0 2 2 2 1 Bacterial transcriptional activator domain TPR_16 PF13432.6 CBK23695.2 - 0.012 16.2 0.0 0.54 11.0 0.0 2.4 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.6 CBK23695.2 - 0.017 15.7 0.2 8.2 7.3 0.0 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat RPN7 PF10602.9 CBK23695.2 - 0.062 13.0 0.2 1 9.1 0.0 2.0 1 1 1 2 2 2 0 26S proteasome subunit RPN7 TPR_10 PF13374.6 CBK23695.2 - 0.067 13.1 0.2 14 5.7 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_9 PF13371.6 CBK23695.2 - 0.11 12.7 0.0 0.38 10.9 0.0 1.7 1 1 1 2 2 2 0 Tetratricopeptide repeat YchF-GTPase_C PF06071.13 CBK23696.2 - 4.3e-30 103.7 0.5 7.9e-30 102.9 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.23 CBK23696.2 - 2.3e-06 27.7 0.0 5.9e-06 26.3 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase TGS PF02824.21 CBK23696.2 - 0.032 14.3 0.0 0.057 13.5 0.0 1.5 1 0 0 1 1 1 0 TGS domain zf-CCHC PF00098.23 CBK23697.2 - 3.6e-31 105.8 50.0 6.7e-07 29.1 2.2 6.9 7 0 0 7 7 7 6 Zinc knuckle zf-C2H2_10 PF16588.5 CBK23697.2 - 3.8e-07 29.7 43.1 0.0093 15.7 2.5 6.2 4 1 2 6 6 6 4 C2H2 zinc-finger zf-CCHC_3 PF13917.6 CBK23697.2 - 8.5e-07 28.8 37.0 0.1 12.6 0.7 6.2 3 1 3 6 6 6 5 Zinc knuckle zf-CCHC_2 PF13696.6 CBK23697.2 - 2.1e-06 27.4 50.7 0.0062 16.3 4.0 6.8 7 0 0 7 7 7 6 Zinc knuckle zf-CCHC_4 PF14392.6 CBK23697.2 - 1.4e-05 24.7 31.2 0.1 12.3 1.5 6.1 6 0 0 6 6 6 5 Zinc knuckle Ras PF00071.22 CBK23698.2 - 1.3e-21 76.9 0.0 1.9e-21 76.4 0.0 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CBK23698.2 - 3e-09 37.1 0.0 5.4e-09 36.3 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 CBK23698.2 - 0.0003 20.9 0.0 0.00054 20.0 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.6 CBK23698.2 - 0.0024 18.1 0.1 0.0084 16.4 0.0 1.9 2 1 0 2 2 2 1 AAA domain Herpes_UL69 PF05459.12 CBK23698.2 - 0.023 14.1 2.1 0.054 12.8 0.0 2.5 2 1 1 3 3 3 0 Herpesvirus transcriptional regulator family AAA_16 PF13191.6 CBK23698.2 - 0.023 15.1 0.0 0.18 12.2 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain Cytochrom_C_asm PF01578.20 CBK23698.2 - 0.091 12.5 0.0 0.11 12.2 0.0 1.2 1 0 0 1 1 1 0 Cytochrome C assembly protein NB-ARC PF00931.22 CBK23698.2 - 0.1 11.7 0.0 1.7 7.8 0.0 2.2 2 0 0 2 2 2 0 NB-ARC domain ABC_tran PF00005.27 CBK23698.2 - 0.12 12.9 0.0 0.25 11.9 0.0 1.5 1 0 0 1 1 1 0 ABC transporter RsgA_GTPase PF03193.16 CBK23698.2 - 0.14 12.1 0.0 0.43 10.5 0.0 1.8 2 0 0 2 2 2 0 RsgA GTPase AAA_18 PF13238.6 CBK23698.2 - 0.14 12.7 0.0 1.6 9.3 0.0 2.3 2 1 0 2 2 2 0 AAA domain Pigment_DH PF06324.11 CBK23698.2 - 0.17 12.0 0.3 0.41 10.8 0.3 1.7 1 0 0 1 1 1 0 Pigment-dispersing hormone (PDH) NACHT PF05729.12 CBK23698.2 - 0.35 10.8 2.6 0.41 10.5 0.1 2.4 3 1 0 3 3 3 0 NACHT domain Arc_trans_TRASH PF08394.10 CBK23698.2 - 1.2 9.5 5.6 1.5 9.3 2.9 2.6 2 1 0 2 2 2 0 Archaeal TRASH domain tRNA-synt_1 PF00133.22 CBK23699.2 - 5e-204 679.0 0.0 5.4e-203 675.6 0.0 2.0 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 CBK23699.2 - 1.8e-42 144.9 0.2 4.6e-42 143.6 0.2 1.7 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 CBK23699.2 - 1.8e-16 59.9 0.5 2e-07 30.1 0.0 4.4 3 2 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.6 CBK23699.2 - 1.6e-13 50.6 0.1 1.8e-09 37.4 0.0 2.7 1 1 1 2 2 2 2 Leucyl-tRNA synthetase, Domain 2 Val_tRNA-synt_C PF10458.9 CBK23699.2 - 0.0016 18.7 7.4 0.0016 18.7 7.4 2.5 2 0 0 2 2 2 1 Valyl tRNA synthetase tRNA binding arm tRNA-synt_1e PF01406.19 CBK23699.2 - 0.021 14.2 0.0 0.22 10.8 0.0 2.2 2 0 0 2 2 2 0 tRNA synthetases class I (C) catalytic domain Jag_N PF14804.6 CBK23699.2 - 0.069 13.5 0.7 0.17 12.3 0.7 1.6 1 0 0 1 1 1 0 Jag N-terminus ABC_tran_CTD PF16326.5 CBK23699.2 - 0.12 12.7 5.9 0.82 10.0 5.9 2.6 1 0 0 1 1 1 0 ABC transporter C-terminal domain CYTH PF01928.21 CBK23700.2 - 7.8e-08 32.4 0.0 7.8e-08 32.4 0.0 1.0 1 0 0 1 1 1 1 CYTH domain SLAM PF06214.11 CBK23700.2 - 0.21 11.6 0.0 0.24 11.4 0.0 1.1 1 0 0 1 1 1 0 Signaling lymphocytic activation molecule (SLAM) protein PHP PF02811.19 CBK23701.2 - 0.00067 20.0 0.0 0.00097 19.5 0.0 1.5 1 1 0 1 1 1 1 PHP domain AP_endonuc_2 PF01261.24 CBK23701.2 - 0.017 14.6 0.0 0.031 13.7 0.0 1.4 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel PHP_C PF13263.6 CBK23701.2 - 0.2 11.4 0.0 0.56 10.0 0.0 1.8 1 0 0 1 1 1 0 PHP-associated Cpn60_TCP1 PF00118.24 CBK23702.2 - 8e-149 496.4 9.2 9.1e-149 496.2 9.2 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DNA_primase_S PF01896.19 CBK23703.2 - 9.4e-33 113.7 0.2 1.1e-32 113.5 0.2 1.0 1 0 0 1 1 1 1 DNA primase small subunit Rer1 PF03248.13 CBK23704.2 - 1.9e-57 193.7 13.9 2.3e-57 193.5 13.9 1.1 1 0 0 1 1 1 1 Rer1 family ANF_receptor PF01094.28 CBK23705.2 - 3.3e-16 59.4 0.1 3.9e-16 59.1 0.1 1.0 1 0 0 1 1 1 1 Receptor family ligand binding region DUF444 PF04285.12 CBK23705.2 - 0.12 11.4 0.0 0.14 11.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF444) Na_H_Exchanger PF00999.21 CBK23706.2 - 1.1e-40 139.7 37.5 2.1e-40 138.7 37.5 1.4 1 1 0 1 1 1 1 Sodium/hydrogen exchanger family TNFR_16_TM PF18422.1 CBK23706.2 - 0.091 12.7 1.1 0.26 11.3 0.0 2.4 2 0 0 2 2 2 0 Tumor necrosis factor receptor member 16 trans-membrane domain TGT PF01702.18 CBK23707.2 - 7.4e-139 462.8 0.0 9.3e-139 462.4 0.0 1.0 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase IRK_C PF17655.1 CBK23708.2 - 8.6e-25 87.3 0.4 5.4e-23 81.5 0.4 2.1 1 1 0 1 1 1 1 Inward rectifier potassium channel C-terminal domain IRK PF01007.20 CBK23708.2 - 6.8e-07 29.2 0.5 1.5e-06 28.1 0.5 1.6 1 0 0 1 1 1 1 Inward rectifier potassium channel transmembrane domain Ion_trans_2 PF07885.16 CBK23708.2 - 0.045 13.7 6.9 0.079 12.9 6.9 1.4 1 0 0 1 1 1 0 Ion channel Skp1 PF01466.19 CBK23709.2 - 6.9e-25 86.9 0.2 1.5e-24 85.8 0.2 1.6 1 0 0 1 1 1 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.15 CBK23709.2 - 1.9e-05 24.7 1.1 4.5e-05 23.5 1.1 1.7 1 0 0 1 1 1 1 Skp1 family, tetramerisation domain DEAD PF00270.29 CBK23710.2 - 1.8e-18 66.9 0.0 5.1e-18 65.5 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CBK23710.2 - 5.8e-16 58.8 0.2 4.8e-15 55.9 0.0 2.5 2 1 1 3 3 3 1 Helicase conserved C-terminal domain RecQ_Zn_bind PF16124.5 CBK23710.2 - 2.6e-13 50.5 7.8 6.2e-13 49.3 7.8 1.7 1 0 0 1 1 1 1 RecQ zinc-binding RQC PF09382.10 CBK23710.2 - 2.1e-07 30.7 0.0 7e-07 29.0 0.0 2.0 1 0 0 1 1 1 1 RQC domain HRDC PF00570.23 CBK23710.2 - 1.3e-05 25.1 0.0 2.9e-05 24.0 0.0 1.6 1 0 0 1 1 1 1 HRDC domain ResIII PF04851.15 CBK23710.2 - 0.00094 19.2 0.0 0.0028 17.7 0.0 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit GHMP_kinases_C PF08544.13 CBK23710.2 - 0.38 11.2 1.0 38 4.7 0.1 3.8 4 0 0 4 4 4 0 GHMP kinases C terminal UNC-79 PF14776.6 CBK23710.2 - 0.75 8.5 5.1 1.2 7.9 4.3 1.5 1 1 1 2 2 2 0 Cation-channel complex subunit UNC-79 UPF0029 PF01205.19 CBK23711.2 - 6.3e-33 113.3 0.0 8.8e-33 112.8 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 NodZ PF05830.11 CBK23712.2 - 5.2e-13 48.5 0.0 6.8e-13 48.1 0.0 1.1 1 0 0 1 1 1 1 Nodulation protein Z (NodZ) Polyhedrin PF00738.18 CBK23712.2 - 0.0071 15.7 0.0 0.012 15.0 0.0 1.3 1 0 0 1 1 1 1 Polyhedrin LepA_C PF06421.12 CBK23713.2 - 1.5e-40 137.6 0.6 2.4e-40 137.0 0.6 1.3 1 0 0 1 1 1 1 GTP-binding protein LepA C-terminus GTP_EFTU PF00009.27 CBK23713.2 - 4.6e-35 120.9 0.1 6.9e-35 120.4 0.1 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.24 CBK23713.2 - 1.9e-14 53.4 0.0 3.6e-14 52.5 0.0 1.5 1 0 0 1 1 1 1 Elongation factor G C-terminus Ras PF00071.22 CBK23713.2 - 8.7e-05 22.2 0.0 0.00032 20.3 0.0 1.9 2 0 0 2 2 2 1 Ras family EFG_II PF14492.6 CBK23713.2 - 0.00032 20.7 0.0 0.00066 19.7 0.0 1.5 1 0 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.25 CBK23713.2 - 0.0043 17.4 0.0 0.051 14.0 0.0 2.5 2 0 0 2 2 2 1 Elongation factor Tu domain 2 PduV-EutP PF10662.9 CBK23713.2 - 0.0047 16.7 0.0 0.0085 15.8 0.0 1.4 1 0 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation RF3_C PF16658.5 CBK23713.2 - 0.0093 15.8 0.0 0.018 14.8 0.0 1.5 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain MMR_HSR1 PF01926.23 CBK23713.2 - 0.016 15.3 0.0 0.036 14.1 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase SRPRB PF09439.10 CBK23713.2 - 0.042 13.3 0.0 0.075 12.5 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Patatin PF01734.22 CBK23714.2 - 1.8e-13 51.2 9.1 3.4e-12 47.0 9.1 2.3 1 1 0 1 1 1 1 Patatin-like phospholipase NanE PF04131.14 CBK23715.2 - 1.7e-61 206.7 0.6 2.5e-61 206.2 0.6 1.2 1 0 0 1 1 1 1 Putative N-acetylmannosamine-6-phosphate epimerase ROK PF00480.20 CBK23715.2 - 1.9e-44 152.3 1.3 6.3e-42 144.0 1.2 2.4 2 1 1 3 3 3 2 ROK family IMPDH PF00478.25 CBK23715.2 - 1.8e-07 30.5 0.1 8.9e-07 28.2 0.1 2.0 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain His_biosynth PF00977.21 CBK23715.2 - 3.7e-06 26.6 0.0 1.1e-05 25.0 0.0 1.7 2 0 0 2 2 2 1 Histidine biosynthesis protein ThiG PF05690.14 CBK23715.2 - 3.1e-05 23.4 0.5 0.0028 17.0 0.2 2.6 2 0 0 2 2 2 1 Thiazole biosynthesis protein ThiG Dus PF01207.17 CBK23715.2 - 0.00019 20.6 0.1 0.00092 18.4 0.0 2.0 1 1 1 2 2 2 1 Dihydrouridine synthase (Dus) NMO PF03060.15 CBK23715.2 - 0.0013 18.2 0.1 0.0022 17.4 0.1 1.4 1 0 0 1 1 1 1 Nitronate monooxygenase Trp_syntA PF00290.20 CBK23715.2 - 0.013 14.4 0.0 0.023 13.6 0.0 1.3 1 0 0 1 1 1 0 Tryptophan synthase alpha chain SOR_SNZ PF01680.17 CBK23715.2 - 0.017 14.9 0.7 0.69 9.7 0.1 2.6 2 1 0 2 2 2 0 SOR/SNZ family FMN_dh PF01070.18 CBK23715.2 - 0.02 14.0 0.0 0.053 12.5 0.0 1.6 1 1 1 2 2 2 0 FMN-dependent dehydrogenase G3P_antiterm PF04309.12 CBK23715.2 - 0.024 14.1 0.1 0.49 9.8 0.0 2.3 2 0 0 2 2 2 0 Glycerol-3-phosphate responsive antiterminator IGPS PF00218.21 CBK23715.2 - 0.043 13.0 0.0 0.079 12.1 0.0 1.5 1 0 0 1 1 1 0 Indole-3-glycerol phosphate synthase Arf PF00025.21 CBK23716.2 - 3.4e-72 241.6 0.1 3.9e-72 241.3 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 CBK23716.2 - 1.2e-12 48.1 0.0 2.2e-12 47.2 0.0 1.4 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 CBK23716.2 - 2.6e-12 46.5 0.0 3.2e-12 46.2 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.22 CBK23716.2 - 6.3e-12 45.4 0.0 7.5e-12 45.1 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.20 CBK23716.2 - 5.1e-11 42.3 1.1 1e-07 31.5 0.3 2.6 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.12 CBK23716.2 - 3.5e-07 29.8 0.0 4.7e-07 29.4 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 CBK23716.2 - 1.5e-05 25.0 0.0 2.9e-05 24.1 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase MeaB PF03308.16 CBK23716.2 - 0.029 13.4 0.2 0.13 11.2 0.4 1.9 2 1 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB FeoB_N PF02421.18 CBK23716.2 - 0.049 13.2 1.0 0.28 10.7 1.0 2.0 1 1 0 1 1 1 0 Ferrous iron transport protein B GTP_EFTU PF00009.27 CBK23716.2 - 0.14 11.7 0.6 1.6 8.3 0.2 2.1 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain MobB PF03205.14 CBK23716.2 - 0.14 12.0 0.0 0.28 11.1 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B DUF4005 PF13178.6 CBK23717.2 - 1.7e-08 35.0 50.8 0.00012 22.7 3.2 7.6 1 1 6 7 7 7 5 Protein of unknown function (DUF4005) HSP70 PF00012.20 CBK23718.2 - 1.2e-98 330.8 0.7 1.4e-98 330.6 0.7 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 CBK23718.2 - 2.3e-10 39.8 0.4 4.9e-09 35.4 0.1 2.9 3 1 0 3 3 3 1 MreB/Mbl protein FGGY_C PF02782.16 CBK23718.2 - 0.00012 21.8 0.0 0.00025 20.8 0.0 1.4 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FtsA PF14450.6 CBK23718.2 - 0.0068 16.8 0.1 1.6 9.2 0.0 3.7 3 1 0 3 3 3 1 Cell division protein FtsA StbA PF06406.11 CBK23718.2 - 0.011 14.9 0.0 0.036 13.3 0.0 1.7 1 1 1 2 2 2 0 StbA protein GARS_A PF01071.19 CBK23719.2 - 5.2e-76 254.7 0.0 9.4e-76 253.9 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain Formyl_trans_N PF00551.19 CBK23719.2 - 4.8e-42 143.7 0.2 1.2e-41 142.5 0.2 1.7 2 0 0 2 2 2 1 Formyl transferase GARS_N PF02844.15 CBK23719.2 - 6.3e-34 116.6 1.5 1e-32 112.8 0.2 2.9 2 0 0 2 2 2 1 Phosphoribosylglycinamide synthetase, N domain AIRS_C PF02769.22 CBK23719.2 - 2.2e-33 115.6 0.1 1e-32 113.4 0.0 2.3 2 0 0 2 2 2 1 AIR synthase related protein, C-terminal domain GARS_C PF02843.16 CBK23719.2 - 3.7e-30 104.1 0.6 1.3e-29 102.3 0.6 2.0 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, C domain AIRS PF00586.24 CBK23719.2 - 1.2e-12 48.3 2.9 2.7e-12 47.2 0.7 2.6 2 0 0 2 2 2 1 AIR synthase related protein, N-terminal domain CPSase_L_D2 PF02786.17 CBK23719.2 - 5.2e-05 22.8 0.0 0.0001 21.8 0.0 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain ATP-grasp_3 PF02655.14 CBK23719.2 - 0.002 18.2 0.0 0.0059 16.7 0.0 1.8 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp PF02222.22 CBK23719.2 - 0.006 16.2 0.0 0.012 15.1 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_5 PF13549.6 CBK23719.2 - 0.011 15.2 0.0 0.024 14.1 0.0 1.5 1 0 0 1 1 1 0 ATP-grasp domain LAL_C2 PF18603.1 CBK23719.2 - 0.02 15.1 0.4 0.16 12.1 0.1 2.5 2 0 0 2 2 2 0 L-amino acid ligase C-terminal domain 2 He_PIG PF05345.12 CBK23721.2 - 1.5e-15 57.1 31.1 5.2e-05 23.4 0.1 5.5 5 1 0 5 5 5 4 Putative Ig domain DUF11 PF01345.18 CBK23721.2 - 1.3e-05 25.4 0.0 0.64 10.4 0.0 4.4 2 2 0 2 2 2 2 Domain of unknown function DUF11 I-set PF07679.16 CBK23721.2 - 0.00018 21.5 5.5 2 8.5 0.1 4.3 4 0 0 4 4 4 2 Immunoglobulin I-set domain HRM PF02793.22 CBK23721.2 - 0.064 13.6 16.1 0.3 11.4 0.1 5.2 5 0 0 5 5 5 0 Hormone receptor domain ComP_DUS PF16732.5 CBK23721.2 - 0.11 13.4 2.9 1e+02 3.9 0.0 3.9 4 0 0 4 4 4 0 Type IV minor pilin ComP, DNA uptake sequence receptor DUF3185 PF11381.8 CBK23721.2 - 0.86 9.7 7.8 2.3 8.3 7.8 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3185) Arch_flagellin PF01917.16 CBK23721.2 - 2 8.6 8.7 5.1 7.3 3.8 3.3 2 1 0 2 2 2 0 Archaebacterial flagellin PQ-loop PF04193.14 CBK23723.2 - 8.3e-24 83.1 14.1 1.8e-18 66.1 6.2 3.4 4 0 0 4 4 4 2 PQ loop repeat PAP2_C PF14360.6 CBK23723.2 - 0.0045 17.5 2.5 0.0045 17.5 2.5 2.9 3 2 1 4 4 4 1 PAP2 superfamily C-terminal GAPT PF11770.8 CBK23723.2 - 0.49 10.2 1.8 0.94 9.3 1.8 1.5 1 0 0 1 1 1 0 GRB2-binding adapter (GAPT) Tim17 PF02466.19 CBK23725.2 - 4.4e-07 30.3 0.5 5.8e-07 29.9 0.5 1.3 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family CbtA PF09490.10 CBK23725.2 - 0.032 14.0 0.1 9 6.0 0.0 2.9 2 1 1 3 3 3 0 Probable cobalt transporter subunit (CbtA) ThrE PF06738.12 CBK23725.2 - 0.034 13.5 0.7 0.049 13.0 0.1 1.5 2 0 0 2 2 2 0 Putative threonine/serine exporter Romo1 PF10247.9 CBK23725.2 - 0.061 13.7 0.8 3.8 7.9 0.0 2.6 2 1 0 2 2 2 0 Reactive mitochondrial oxygen species modulator 1 GDI PF00996.18 CBK23726.2 - 3.7e-181 602.4 0.0 4.4e-181 602.1 0.0 1.0 1 0 0 1 1 1 1 GDP dissociation inhibitor NAD_binding_8 PF13450.6 CBK23726.2 - 0.00038 20.6 0.0 0.00083 19.5 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pkinase PF00069.25 CBK23727.2 - 1.4e-45 155.7 0.0 1.6e-45 155.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBK23727.2 - 2e-31 109.2 0.0 2.5e-31 108.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CBK23727.2 - 5.3e-08 32.0 0.0 7.3e-08 31.6 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 CBK23727.2 - 0.0033 16.4 0.0 0.0053 15.8 0.0 1.3 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 CBK23727.2 - 0.012 15.0 0.0 0.017 14.5 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 CBK23727.2 - 0.11 11.8 0.0 0.16 11.2 0.0 1.2 1 0 0 1 1 1 0 Kinase-like APH PF01636.23 CBK23727.2 - 0.17 11.8 0.0 0.31 10.9 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family DUF1933 PF09147.10 CBK23728.2 - 0.1 12.2 0.1 0.19 11.3 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1933) Pro_isomerase PF00160.21 CBK23729.2 - 5.6e-41 140.4 0.5 9.3e-41 139.7 0.5 1.4 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RRM_1 PF00076.22 CBK23729.2 - 9.6e-17 60.6 0.1 2.7e-16 59.1 0.1 1.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HMG-CoA_red PF00368.18 CBK23730.2 - 3.5e-112 375.1 0.4 4.1e-112 374.8 0.4 1.0 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A reductase Tubulin PF00091.25 CBK23731.2 - 5.9e-64 215.9 0.0 1.1e-63 215.1 0.0 1.4 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 CBK23731.2 - 2.4e-41 140.9 1.5 2.4e-41 140.8 0.4 1.6 2 0 0 2 2 2 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 CBK23731.2 - 0.00018 21.8 0.0 0.00093 19.5 0.0 2.1 1 1 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_2 PF13809.6 CBK23731.2 - 0.028 13.6 0.0 0.049 12.8 0.0 1.3 1 0 0 1 1 1 0 Tubulin like BolA PF01722.18 CBK23732.2 - 8e-11 42.1 0.0 1.5e-10 41.2 0.0 1.5 1 0 0 1 1 1 1 BolA-like protein CTP_transf_like PF01467.26 CBK23732.2 - 6.9e-09 36.0 0.0 2.1e-08 34.5 0.0 1.7 1 1 1 2 2 2 1 Cytidylyltransferase-like Myb_DNA-binding PF00249.31 CBK23733.2 - 7.8e-13 48.4 0.1 1.1e-12 47.9 0.1 1.3 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 CBK23733.2 - 1.4e-06 28.4 0.3 2.5e-06 27.6 0.3 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 CBK23733.2 - 1.5e-05 24.8 1.2 2.9e-05 23.9 0.8 1.7 2 1 0 2 2 2 1 Myb DNA-binding like Interferon PF00143.19 CBK23733.2 - 0.073 13.2 0.6 0.11 12.7 0.6 1.1 1 0 0 1 1 1 0 Interferon alpha/beta domain RGS12_usC PF16612.5 CBK23733.2 - 0.3 11.5 3.5 0.31 11.5 2.1 1.7 1 1 1 2 2 2 0 C-terminal unstructured region of RGS12 Thioredoxin PF00085.20 CBK23734.2 - 2e-64 214.0 0.2 7.8e-31 106.1 0.0 2.5 2 0 0 2 2 2 2 Thioredoxin OST3_OST6 PF04756.13 CBK23734.2 - 8.1e-18 64.8 0.0 2.8e-12 46.6 0.0 2.3 2 0 0 2 2 2 2 OST3 / OST6 family, transporter family ERp29 PF07749.12 CBK23734.2 - 1.5e-16 61.1 2.0 5.8e-16 59.2 2.2 1.9 2 0 0 2 2 2 1 Endoplasmic reticulum protein ERp29, C-terminal domain Thioredoxin_2 PF13098.6 CBK23734.2 - 3.5e-14 53.2 2.3 1.7e-06 28.4 0.0 3.3 3 1 0 3 3 3 2 Thioredoxin-like domain Thioredoxin_8 PF13905.6 CBK23734.2 - 3.7e-12 46.4 0.2 0.00041 20.6 0.0 3.6 2 1 1 3 3 3 2 Thioredoxin-like AhpC-TSA PF00578.21 CBK23734.2 - 6.9e-11 42.1 0.6 0.00018 21.4 0.1 2.6 2 1 0 2 2 2 2 AhpC/TSA family Thioredoxin_7 PF13899.6 CBK23734.2 - 1.9e-10 40.7 0.1 0.00064 19.9 0.0 2.5 2 0 0 2 2 2 2 Thioredoxin-like ERp29_N PF07912.13 CBK23734.2 - 2.8e-07 30.7 0.4 0.0052 16.9 0.0 2.3 1 1 1 2 2 2 2 ERp29, N-terminal domain Redoxin PF08534.10 CBK23734.2 - 3.2e-07 30.1 0.2 0.0041 16.9 0.1 2.4 2 0 0 2 2 2 2 Redoxin Thioredoxin_6 PF13848.6 CBK23734.2 - 8.5e-05 22.5 4.3 0.0015 18.5 0.1 3.7 3 1 0 3 3 3 1 Thioredoxin-like domain HyaE PF07449.11 CBK23734.2 - 0.00039 20.3 0.0 0.33 10.9 0.0 2.5 2 0 0 2 2 2 2 Hydrogenase-1 expression protein HyaE TraF PF13728.6 CBK23734.2 - 0.0042 16.9 0.0 2.9 7.7 0.0 2.9 3 0 0 3 3 3 1 F plasmid transfer operon protein DUF445 PF04286.12 CBK23734.2 - 0.025 14.4 2.6 0.08 12.7 2.3 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF445) SQS_PSY PF00494.19 CBK23734.2 - 0.034 13.6 0.0 0.057 12.9 0.0 1.3 1 0 0 1 1 1 0 Squalene/phytoene synthase V_ATPase_I PF01496.19 CBK23734.2 - 0.047 11.6 0.0 0.066 11.1 0.0 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Prok-E2_C PF14459.6 CBK23734.2 - 0.077 13.2 0.0 4.6 7.4 0.0 2.3 2 0 0 2 2 2 0 Prokaryotic E2 family C Glutaredoxin PF00462.24 CBK23734.2 - 0.1 12.8 8.8 3.2 8.0 2.2 3.8 2 2 0 2 2 2 0 Glutaredoxin DDE_Tnp_1_2 PF13586.6 CBK23734.2 - 0.11 12.9 0.0 9.2 6.7 0.0 2.7 2 0 0 2 2 2 0 Transposase DDE domain PvlArgDC PF01862.16 CBK23734.2 - 0.12 12.2 0.3 0.2 11.4 0.3 1.3 1 0 0 1 1 1 0 Pyruvoyl-dependent arginine decarboxylase (PvlArgDC) CsbD PF05532.12 CBK23734.2 - 0.27 11.2 2.8 0.61 10.0 2.8 1.6 1 0 0 1 1 1 0 CsbD-like Glyco_trans_1_2 PF13524.6 CBK23734.2 - 3.3 8.2 4.6 26 5.3 0.2 3.5 3 1 0 3 3 3 0 Glycosyl transferases group 1 Ribosom_S12_S23 PF00164.25 CBK23735.2 - 4.2e-48 161.7 1.9 5.1e-48 161.4 1.9 1.2 1 0 0 1 1 1 1 Ribosomal protein S12/S23 PLDc_2 PF13091.6 CBK23736.2 - 0.003 17.5 0.0 0.0038 17.1 0.0 1.2 1 0 0 1 1 1 1 PLD-like domain PLDc PF00614.22 CBK23736.2 - 0.037 14.2 0.5 0.064 13.5 0.5 1.4 1 0 0 1 1 1 0 Phospholipase D Active site motif RRM_1 PF00076.22 CBK23737.2 - 1.1e-09 37.9 0.8 2.9e-09 36.6 0.3 1.9 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) NTF2 PF02136.20 CBK23737.2 - 4.1e-07 30.6 0.7 6.6e-07 29.9 0.3 1.6 2 0 0 2 2 2 1 Nuclear transport factor 2 (NTF2) domain RRM_3 PF08777.11 CBK23737.2 - 0.043 13.9 0.2 0.098 12.7 0.1 1.8 2 0 0 2 2 2 0 RNA binding motif RRM_7 PF16367.5 CBK23737.2 - 0.1 12.7 0.0 0.24 11.5 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif Ribosomal_L27A PF00828.19 CBK23738.2 - 1.1e-22 81.1 0.0 1.5e-22 80.6 0.0 1.2 1 0 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A CTP_transf_like PF01467.26 CBK23739.2 - 3e-32 111.8 0.1 4.6e-32 111.2 0.1 1.3 1 0 0 1 1 1 1 Cytidylyltransferase-like Rsd_AlgQ PF04353.13 CBK23739.2 - 0.0029 17.6 0.0 0.016 15.1 0.0 2.0 2 0 0 2 2 2 1 Regulator of RNA polymerase sigma(70) subunit, Rsd/AlgQ DUF5639 PF18690.1 CBK23739.2 - 0.034 14.3 0.0 0.076 13.2 0.0 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5639) DUF643 PF04867.12 CBK23739.2 - 0.044 14.4 1.3 0.071 13.7 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF643) Kinesin PF00225.23 CBK23740.2 - 3.9e-93 312.0 0.0 3.9e-93 312.0 0.0 1.6 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 CBK23740.2 - 2.6e-47 160.5 0.1 9.9e-47 158.6 0.0 2.0 2 0 0 2 2 2 1 Microtubule binding CP12 PF02672.15 CBK23740.2 - 0.034 14.9 2.0 0.034 14.9 2.0 2.5 2 0 0 2 2 2 0 CP12 domain bZIP_1 PF00170.21 CBK23740.2 - 0.1 12.7 0.4 0.1 12.7 0.4 4.1 2 1 2 4 4 4 0 bZIP transcription factor AAA_22 PF13401.6 CBK23740.2 - 0.12 12.7 1.2 0.5 10.6 0.0 2.4 2 0 0 2 2 2 0 AAA domain NTP_transf_4 PF13562.6 CBK23740.2 - 0.12 12.6 2.9 0.33 11.2 2.9 1.8 1 0 0 1 1 1 0 Sugar nucleotidyl transferase Jnk-SapK_ap_N PF09744.9 CBK23740.2 - 0.52 10.5 33.3 0.8 9.9 19.2 2.6 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 LPP PF04728.13 CBK23740.2 - 0.63 10.5 5.3 6.2 7.3 1.5 3.0 2 0 0 2 2 2 0 Lipoprotein leucine-zipper FapA PF03961.13 CBK23740.2 - 0.7 8.4 13.7 1.1 7.7 13.7 1.3 1 0 0 1 1 1 0 Flagellar Assembly Protein A Speriolin_N PF15058.6 CBK23740.2 - 0.89 9.6 4.6 2.1 8.4 4.6 1.7 1 1 0 1 1 1 0 Speriolin N terminus YabA PF06156.13 CBK23740.2 - 1 10.1 18.7 0.96 10.1 5.6 4.3 2 1 2 4 4 4 0 Initiation control protein YabA DUF3584 PF12128.8 CBK23740.2 - 1.8 5.9 27.1 2.7 5.4 27.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) BLOC1_2 PF10046.9 CBK23740.2 - 2.7 8.4 13.3 2.1 8.7 1.9 3.3 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 UPF0242 PF06785.11 CBK23740.2 - 7.1 6.7 27.4 14 5.7 27.4 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus TPR_MLP1_2 PF07926.12 CBK23740.2 - 7.3 6.7 35.9 0.055 13.5 17.0 2.8 1 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein Mago_nashi PF02792.14 CBK23741.2 - 2.9e-58 196.0 0.6 3.3e-58 195.9 0.6 1.0 1 0 0 1 1 1 1 Mago nashi protein Hexokinase_2 PF03727.16 CBK23743.2 - 5.6e-69 232.2 0.0 6.8e-69 231.9 0.0 1.1 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.21 CBK23743.2 - 2.9e-45 154.6 0.0 4.5e-45 154.0 0.0 1.3 1 0 0 1 1 1 1 Hexokinase ArfGap PF01412.18 CBK23744.2 - 2.8e-24 85.4 0.3 4.5e-24 84.8 0.3 1.3 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf IRF-2BP1_2 PF11261.8 CBK23744.2 - 0.2 11.2 0.3 0.35 10.5 0.3 1.4 1 0 0 1 1 1 0 Interferon regulatory factor 2-binding protein zinc finger Acyltransferase PF01553.21 CBK23745.2 - 5.1e-05 22.9 0.1 0.00027 20.6 0.1 2.0 1 1 0 1 1 1 1 Acyltransferase DUF5312 PF17239.2 CBK23745.2 - 0.1 11.0 0.1 0.13 10.6 0.1 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5312) LRR_8 PF13855.6 CBK23746.2 - 0.00011 21.8 2.9 0.14 11.9 0.2 4.3 3 2 1 4 4 4 3 Leucine rich repeat hSac2 PF12456.8 CBK23746.2 - 0.088 12.5 0.0 11 5.7 0.0 3.1 3 0 0 3 3 3 0 Inositol phosphatase LRR_1 PF00560.33 CBK23746.2 - 2.3 9.1 8.4 70 4.6 0.2 5.1 5 1 0 5 5 5 0 Leucine Rich Repeat Metallophos PF00149.28 CBK23747.2 - 1.1e-36 127.2 0.0 1.8e-36 126.6 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 CBK23747.2 - 3.5e-13 49.8 1.2 6.5e-13 48.9 1.2 1.5 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain DUF1712 PF08217.11 CBK23748.2 - 2.2e-11 43.0 2.8 4.6e-09 35.3 0.1 2.5 3 0 0 3 3 3 2 Fungal domain of unknown function (DUF1712) FPL PF09758.9 CBK23749.2 - 1e-38 132.7 4.7 6.5e-38 130.0 4.7 1.8 1 1 0 1 1 1 1 Uncharacterised conserved protein UME PF08064.13 CBK23749.2 - 0.0056 16.6 0.2 0.0077 16.1 0.2 1.4 1 0 0 1 1 1 1 UME (NUC010) domain ATP-synt_A PF00119.20 CBK23749.2 - 0.065 13.2 0.3 0.078 12.9 0.3 1.2 1 0 0 1 1 1 0 ATP synthase A chain He_PIG PF05345.12 CBK23750.2 - 4.6e-15 55.5 29.9 0.0007 19.7 4.2 5.5 4 2 1 5 5 5 4 Putative Ig domain I-set PF07679.16 CBK23750.2 - 2.9e-05 24.0 4.8 2.2 8.4 0.1 4.5 4 0 0 4 4 4 2 Immunoglobulin I-set domain HRM PF02793.22 CBK23750.2 - 0.00015 22.0 11.6 0.23 11.8 0.2 4.7 4 0 0 4 4 4 2 Hormone receptor domain FeS_assembly_P PF01883.19 CBK23750.2 - 0.011 15.9 0.7 0.93 9.7 0.1 3.4 3 1 0 3 3 3 0 Iron-sulfur cluster assembly protein ComP_DUS PF16732.5 CBK23750.2 - 0.069 14.1 1.8 30 5.6 0.0 3.8 4 0 0 4 4 4 0 Type IV minor pilin ComP, DNA uptake sequence receptor cEGF PF12662.7 CBK23750.2 - 0.45 10.5 2.2 31 4.6 0.1 2.9 2 0 0 2 2 2 0 Complement Clr-like EGF-like CPW_WPC PF09717.10 CBK23750.2 - 0.72 10.9 5.7 8.5 7.4 0.1 4.1 4 1 1 5 5 5 0 Plasmodium falciparum domain of unknown function (CPW_WPC) Asp_protease PF09668.10 CBK23751.2 - 5e-13 48.9 0.0 9e-13 48.1 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 CBK23751.2 - 8.2e-10 39.1 0.2 1.8e-09 38.1 0.2 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 CBK23751.2 - 2.1e-08 34.7 0.2 4.2e-08 33.7 0.2 1.5 1 0 0 1 1 1 1 Aspartyl protease ubiquitin PF00240.23 CBK23751.2 - 2.4e-08 33.6 0.0 4.6e-08 32.7 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family RVP PF00077.20 CBK23751.2 - 4.8e-05 23.6 0.1 0.0004 20.6 0.0 2.2 2 0 0 2 2 2 1 Retroviral aspartyl protease Rad60-SLD PF11976.8 CBK23751.2 - 0.0002 21.1 0.4 0.0013 18.6 0.2 2.2 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like dsDNA_bind PF01984.20 CBK23753.2 - 7.4e-23 80.9 5.2 9.4e-23 80.6 5.2 1.0 1 0 0 1 1 1 1 Double-stranded DNA-binding domain Flu_M2 PF00599.17 CBK23753.2 - 0.057 13.5 0.0 0.088 12.9 0.0 1.3 1 0 0 1 1 1 0 Influenza Matrix protein (M2) CTP_transf_like PF01467.26 CBK23753.2 - 0.07 13.3 0.1 0.096 12.9 0.1 1.1 1 0 0 1 1 1 0 Cytidylyltransferase-like Tom5 PF10642.9 CBK23753.2 - 0.2 11.7 1.4 0.46 10.6 1.4 1.5 1 0 0 1 1 1 0 Mitochondrial import receptor subunit or translocase Comm PF15957.5 CBK23753.2 - 0.41 11.0 3.6 0.27 11.6 1.9 1.6 2 0 0 2 2 2 0 Commissureless RCC1 PF00415.18 CBK23754.2 - 1.4e-38 131.3 14.0 3e-14 53.4 0.2 6.5 7 0 0 7 7 7 4 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 CBK23754.2 - 2.9e-26 90.6 22.9 1.4e-06 27.9 0.0 6.3 6 0 0 6 6 6 5 Regulator of chromosome condensation (RCC1) repeat Peptidase_C1 PF00112.23 CBK23755.2 - 1.3e-11 45.0 0.0 2.5e-11 44.1 0.0 1.3 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 CBK23755.2 - 0.0092 16.4 0.7 0.018 15.5 0.7 1.4 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) MFS_1 PF07690.16 CBK23756.2 - 1.5e-22 80.0 27.0 1.1e-21 77.2 25.3 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily MFS_4 PF06779.14 CBK23756.2 - 5.1e-06 26.0 5.1 7.6e-06 25.5 5.1 1.3 1 0 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB Proton_antipo_N PF00662.20 CBK23756.2 - 0.0031 17.6 1.8 0.12 12.5 0.0 3.1 2 0 0 2 2 2 1 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus MFS_1_like PF12832.7 CBK23756.2 - 1 8.1 23.3 7.3 5.3 4.9 2.4 1 1 1 2 2 2 0 MFS_1 like family zf-C2H2 PF00096.26 CBK23757.2 - 1.3e-09 37.9 12.9 0.00021 21.5 2.3 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type HMG_box_2 PF09011.10 CBK23757.2 - 2e-09 37.9 0.7 4.5e-09 36.8 0.7 1.6 1 0 0 1 1 1 1 HMG-box domain HMG_box PF00505.19 CBK23757.2 - 2.2e-08 34.4 0.6 4.4e-08 33.4 0.6 1.5 1 0 0 1 1 1 1 HMG (high mobility group) box zf-C2H2_4 PF13894.6 CBK23757.2 - 2.1e-06 28.1 10.7 0.0037 18.0 2.2 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-Di19 PF05605.12 CBK23757.2 - 0.0057 16.9 6.5 0.02 15.2 6.5 1.9 1 1 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding zf-met PF12874.7 CBK23757.2 - 0.017 15.5 10.2 0.78 10.2 1.3 2.8 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-H2C2_2 PF13465.6 CBK23757.2 - 0.042 14.3 15.5 0.15 12.5 0.7 3.4 3 0 0 3 3 3 0 Zinc-finger double domain zf-C2H2_jaz PF12171.8 CBK23757.2 - 0.64 10.4 14.8 0.45 10.9 3.6 2.5 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding Syntaxin-6_N PF09177.11 CBK23759.2 - 0.0033 17.9 0.3 0.015 15.9 0.2 1.9 2 0 0 2 2 2 1 Syntaxin 6, N-terminal DUF2205 PF10224.9 CBK23759.2 - 0.015 15.3 0.2 0.033 14.2 0.2 1.5 1 0 0 1 1 1 0 Short coiled-coil protein DivIC PF04977.15 CBK23759.2 - 0.024 14.4 0.2 1.6 8.6 0.0 2.3 2 0 0 2 2 2 0 Septum formation initiator CHASE3 PF05227.13 CBK23759.2 - 0.043 13.7 0.7 0.069 13.1 0.7 1.2 1 0 0 1 1 1 0 CHASE3 domain DinB_2 PF12867.7 CBK23759.2 - 0.078 13.5 0.2 0.11 13.0 0.2 1.3 1 0 0 1 1 1 0 DinB superfamily MerR-DNA-bind PF09278.11 CBK23759.2 - 0.36 11.4 4.1 0.86 10.2 4.1 1.7 1 0 0 1 1 1 0 MerR, DNA binding RbsD_FucU PF05025.13 CBK23760.2 - 4.6e-21 75.6 0.0 5e-21 75.5 0.0 1.0 1 0 0 1 1 1 1 RbsD / FucU transport protein family PHD PF00628.29 CBK23761.2 - 6.8e-07 29.1 5.1 6.8e-07 29.1 5.1 2.2 3 0 0 3 3 3 1 PHD-finger PHD_2 PF13831.6 CBK23761.2 - 9.5e-05 21.9 4.0 9.5e-05 21.9 4.0 2.5 4 0 0 4 4 4 1 PHD-finger zf-HC5HC2H_2 PF13832.6 CBK23761.2 - 0.0011 19.1 0.0 0.0011 19.1 0.0 3.2 3 0 0 3 3 3 1 PHD-zinc-finger like domain Myb_DNA-bind_6 PF13921.6 CBK23761.2 - 0.19 12.0 2.4 0.61 10.4 2.4 1.8 1 1 0 1 1 1 0 Myb-like DNA-binding domain zf-PHD-like PF15446.6 CBK23761.2 - 1.5 8.5 9.9 2.6 7.7 8.3 2.2 2 1 0 2 2 2 0 PHD/FYVE-zinc-finger like domain Prok-RING_1 PF14446.6 CBK23761.2 - 3.8 7.5 15.1 0.08 12.9 5.1 3.1 4 0 0 4 4 4 0 Prokaryotic RING finger family 1 PHD PF00628.29 CBK23762.2 - 2.7e-07 30.4 8.8 2.7e-07 30.4 8.8 2.6 2 0 0 2 2 2 1 PHD-finger Zf_RING PF16744.5 CBK23762.2 - 5.5e-05 23.2 5.1 5.5e-05 23.2 5.1 2.2 2 0 0 2 2 2 1 KIAA1045 RING finger C1_1 PF00130.22 CBK23762.2 - 0.0066 16.3 17.1 0.027 14.4 5.2 3.2 3 0 0 3 3 3 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Baculo_Y142 PF04913.12 CBK23762.2 - 0.18 10.5 0.0 0.22 10.2 0.0 1.1 1 0 0 1 1 1 0 Baculovirus Y142 protein zf-BED PF02892.15 CBK23762.2 - 0.3 11.1 0.0 0.3 11.1 0.0 3.6 2 2 2 4 4 4 0 BED zinc finger C1_2 PF03107.16 CBK23762.2 - 4.3 7.7 23.5 0.18 12.1 7.8 3.4 3 1 0 3 3 3 0 C1 domain Spec3 PF15795.5 CBK23763.2 - 6.7e-07 29.8 10.0 0.00091 19.7 0.1 2.1 2 0 0 2 2 2 2 Ectodermal ciliogenesis protein LapA_dom PF06305.11 CBK23763.2 - 4.3 7.2 7.4 0.55 10.1 2.5 1.8 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain Pkinase PF00069.25 CBK23764.2 - 1.1e-46 159.3 0.0 1.8e-46 158.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBK23764.2 - 3.4e-17 62.6 0.0 5.1e-17 62.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 CBK23764.2 - 2.8e-05 24.2 0.1 6.4e-05 23.0 0.0 1.6 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 CBK23764.2 - 0.0087 15.4 0.2 0.015 14.7 0.2 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 CBK23764.2 - 0.11 12.1 0.0 0.18 11.4 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase NFACT-R_1 PF05670.13 CBK23765.2 - 1.5e-24 86.7 0.0 9.1e-24 84.2 0.0 2.3 2 0 0 2 2 2 1 NFACT protein RNA binding domain NFACT-C PF11923.8 CBK23765.2 - 3.5e-17 62.3 0.0 3.5e-17 62.3 0.0 2.9 2 0 0 2 2 2 1 NFACT protein C-terminal domain zf-CCHC PF00098.23 CBK23765.2 - 0.03 14.4 1.0 0.06 13.5 1.0 1.5 1 0 0 1 1 1 0 Zinc knuckle YL1 PF05764.13 CBK23765.2 - 2.7 8.0 34.1 0.23 11.5 11.2 2.7 2 0 0 2 2 2 0 YL1 nuclear protein FbpA PF05833.11 CBK23766.2 - 1.7e-29 102.9 0.1 1.8e-29 102.8 0.1 1.0 1 0 0 1 1 1 1 Fibronectin-binding protein A N-terminus (FbpA) Fe_hyd_lg_C PF02906.14 CBK23766.2 - 0.074 12.7 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 Iron only hydrogenase large subunit, C-terminal domain PHD PF00628.29 CBK23767.2 - 1.1e-09 38.0 10.3 1.5e-09 37.6 10.3 1.2 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 CBK23767.2 - 0.00026 20.5 2.8 0.00026 20.5 2.8 1.8 2 0 0 2 2 2 1 PHD-finger zf-PHD-like PF15446.6 CBK23767.2 - 0.028 14.1 3.2 0.028 14.1 3.2 1.6 1 1 0 1 1 1 0 PHD/FYVE-zinc-finger like domain PHD_4 PF16866.5 CBK23767.2 - 6 7.0 13.4 56 3.9 13.4 2.3 1 1 0 1 1 1 0 PHD-finger HMG_box PF00505.19 CBK23768.2 - 3.4e-07 30.6 6.7 9.5e-07 29.1 6.7 1.8 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 CBK23768.2 - 6.1e-07 29.9 5.9 1.2e-06 29.0 5.9 1.5 1 0 0 1 1 1 1 HMG-box domain Protamine_like PF06382.11 CBK23768.2 - 0.011 15.9 0.2 0.069 13.3 0.1 2.0 2 0 0 2 2 2 0 Protamine and protamine like HMG_box_5 PF14887.6 CBK23768.2 - 0.031 14.2 1.0 0.057 13.4 1.0 1.4 1 0 0 1 1 1 0 HMG (high mobility group) box 5 PGBA_C PF15437.6 CBK23768.2 - 0.38 11.2 4.9 0.84 10.0 4.9 1.5 1 0 0 1 1 1 0 Plasminogen-binding protein pgbA C-terminal zf-C2H2_4 PF13894.6 CBK23769.2 - 1.4e-09 38.0 9.6 0.001 19.7 0.5 3.5 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2 PF00096.26 CBK23769.2 - 5.9e-09 35.9 12.4 0.00013 22.2 0.8 3.3 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_aberr PF17017.5 CBK23769.2 - 1.1e-07 32.1 3.1 0.00055 20.1 0.4 2.4 1 1 1 2 2 2 2 Aberrant zinc-finger zf-C2H2_6 PF13912.6 CBK23769.2 - 2.3e-07 30.6 9.2 0.001 19.0 0.1 3.6 3 0 0 3 3 3 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 CBK23769.2 - 4.6e-07 30.0 12.8 0.0007 19.9 0.5 3.3 3 0 0 3 3 3 2 Zinc-finger double domain zf-Di19 PF05605.12 CBK23769.2 - 1.1e-05 25.6 3.8 0.0013 19.0 0.7 2.3 1 1 1 2 2 2 2 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_8 PF15909.5 CBK23769.2 - 1.6e-05 25.1 2.8 7.4e-05 23.0 2.7 1.9 1 1 1 2 2 2 2 C2H2-type zinc ribbon FOXP-CC PF16159.5 CBK23769.2 - 0.00013 22.5 1.2 0.032 14.8 0.1 2.4 1 1 1 2 2 2 2 FOXP coiled-coil domain zf-C2H2_jaz PF12171.8 CBK23769.2 - 0.047 14.0 10.8 0.7 10.3 1.5 3.9 3 1 0 3 3 3 0 Zinc-finger double-stranded RNA-binding CCAP PF11105.8 CBK23769.2 - 0.086 12.8 2.2 0.24 11.4 0.9 2.1 1 1 1 2 2 2 0 Arthropod cardioacceleratory peptide 2a Ribosomal_L37ae PF01780.19 CBK23769.2 - 1.8 8.7 4.8 9 6.5 0.4 2.6 1 1 1 2 2 2 0 Ribosomal L37ae protein family HSP70 PF00012.20 CBK23772.2 - 1.1e-83 281.4 0.1 1.4e-83 281.1 0.1 1.1 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 CBK23772.2 - 2.5e-10 39.7 0.3 1.1e-05 24.4 0.0 2.7 3 0 0 3 3 3 2 MreB/Mbl protein Actin PF00022.19 CBK23772.2 - 0.0021 16.8 0.0 0.57 8.7 0.0 2.1 2 0 0 2 2 2 2 Actin StbA PF06406.11 CBK23772.2 - 0.041 13.1 0.0 0.37 10.0 0.0 2.1 2 0 0 2 2 2 0 StbA protein DDR PF08841.10 CBK23772.2 - 0.16 10.9 0.1 5.5 5.9 0.0 2.2 2 0 0 2 2 2 0 Diol dehydratase reactivase ATPase-like domain RRM_1 PF00076.22 CBK23773.2 - 1.1e-11 44.3 0.0 2e-11 43.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) WD40_3 PF15911.5 CBK23773.2 - 0.084 12.9 0.1 1.8 8.6 0.0 2.3 2 0 0 2 2 2 0 WD domain, G-beta repeat RRM_3 PF08777.11 CBK23773.2 - 0.091 12.8 0.0 0.14 12.2 0.0 1.3 1 0 0 1 1 1 0 RNA binding motif NIPSNAP PF07978.13 CBK23773.2 - 0.17 12.1 0.0 0.27 11.5 0.0 1.2 1 0 0 1 1 1 0 NIPSNAP TED_complement PF07678.14 CBK23774.2 - 7.4e-11 41.6 0.0 1.4e-10 40.7 0.0 1.4 1 0 0 1 1 1 1 A-macroglobulin TED domain A2M_recep PF07677.14 CBK23774.2 - 5.4e-05 23.8 0.1 0.00016 22.3 0.1 1.8 1 0 0 1 1 1 1 A-macroglobulin receptor binding domain bMG10 PF17973.1 CBK23774.2 - 9.8e-05 22.6 0.2 0.00029 21.0 0.2 1.8 1 0 0 1 1 1 1 Bacterial Alpha-2-macroglobulin MG10 domain Arrestin_C PF02752.22 CBK23774.2 - 0.042 14.3 0.1 10 6.6 0.0 2.8 2 0 0 2 2 2 0 Arrestin (or S-antigen), C-terminal domain MG2 PF01835.19 CBK23774.2 - 0.062 13.8 0.0 0.5 10.9 0.0 2.6 2 0 0 2 2 2 0 MG2 domain PIN_4 PF13638.6 CBK23774.2 - 0.12 12.6 0.0 0.46 10.8 0.0 2.0 1 0 0 1 1 1 0 PIN domain EF-hand_4 PF12763.7 CBK23775.2 - 4.1e-11 42.7 0.1 1.2e-10 41.3 0.0 1.7 2 1 0 2 2 2 1 Cytoskeletal-regulatory complex EF hand EF-hand_1 PF00036.32 CBK23775.2 - 2.3e-08 33.0 0.1 0.0016 17.9 0.0 3.4 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.6 CBK23775.2 - 2.1e-07 30.3 0.2 0.046 13.7 0.0 3.5 3 0 0 3 3 3 2 EF-hand domain EF-hand_7 PF13499.6 CBK23775.2 - 4.5e-06 27.0 2.9 4.6e-05 23.8 0.1 2.9 2 1 0 2 2 2 1 EF-hand domain pair Laminin_II PF06009.12 CBK23775.2 - 0.0014 18.6 2.3 0.0021 18.1 2.3 1.2 1 0 0 1 1 1 1 Laminin Domain II GAS PF13851.6 CBK23775.2 - 0.0068 15.8 6.6 0.011 15.1 6.6 1.2 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding DHR10 PF18595.1 CBK23775.2 - 0.01 15.9 5.2 0.016 15.2 5.2 1.3 1 0 0 1 1 1 0 Designed helical repeat protein 10 domain Spc7 PF08317.11 CBK23775.2 - 0.022 13.7 5.9 0.029 13.2 5.9 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein FAM76 PF16046.5 CBK23775.2 - 0.023 14.1 3.5 0.027 13.9 3.5 1.1 1 0 0 1 1 1 0 FAM76 protein DUF3213 PF11491.8 CBK23775.2 - 0.1 12.8 1.6 0.18 12.0 0.9 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3213) CENP-H PF05837.12 CBK23775.2 - 0.1 13.0 5.1 0.16 12.4 5.1 1.3 1 0 0 1 1 1 0 Centromere protein H (CENP-H) EF-hand_5 PF13202.6 CBK23775.2 - 0.13 11.8 2.3 14 5.4 0.0 4.1 5 0 0 5 5 5 0 EF hand Syntaxin-6_N PF09177.11 CBK23775.2 - 0.94 10.1 5.9 1.1 9.9 3.9 2.2 2 1 0 2 2 2 0 Syntaxin 6, N-terminal PHD PF00628.29 CBK23776.2 - 5.1e-09 35.9 2.4 1e-08 35.0 2.4 1.5 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.6 CBK23776.2 - 0.0046 17.2 2.0 0.0046 17.2 0.2 2.0 2 1 0 2 2 2 1 PHD-like zinc-binding domain PHD_2 PF13831.6 CBK23776.2 - 0.012 15.2 0.7 0.012 15.2 0.7 1.6 2 0 0 2 2 2 0 PHD-finger zf-RING_2 PF13639.6 CBK23776.2 - 0.25 11.7 2.6 0.53 10.7 2.6 1.6 1 0 0 1 1 1 0 Ring finger domain Zf_RING PF16744.5 CBK23776.2 - 1.4 9.1 5.8 1.9 8.6 3.0 2.6 2 1 0 2 2 2 0 KIAA1045 RING finger DUF4829 PF16111.5 CBK23777.2 - 0.22 12.3 9.3 0.25 12.1 9.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4829) CAC1F_C PF16885.5 CBK23777.2 - 0.23 11.1 4.0 0.26 10.9 4.0 1.0 1 0 0 1 1 1 0 Voltage-gated calcium channel subunit alpha, C-term OAD_gamma PF04277.13 CBK23777.2 - 0.36 11.5 4.2 0.42 11.2 4.2 1.2 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain AP3D1 PF06375.11 CBK23777.2 - 1.7 8.8 14.1 2.5 8.3 14.1 1.3 1 0 0 1 1 1 0 AP-3 complex subunit delta-1 Sec62 PF03839.16 CBK23777.2 - 8.8 5.8 13.4 8.8 5.8 13.4 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 Ribosomal_S26e PF01283.19 CBK23778.2 - 8.5e-48 161.3 9.1 9.1e-48 161.2 9.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S26e Fer4_7 PF12838.7 CBK23778.2 - 0.00057 20.4 1.0 0.045 14.3 0.3 2.2 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_6 PF12837.7 CBK23778.2 - 0.0073 16.3 2.9 0.043 13.9 0.8 2.2 2 0 0 2 2 2 1 4Fe-4S binding domain SRP19 PF01922.17 CBK23778.2 - 0.0073 17.2 0.2 0.011 16.7 0.2 1.3 1 0 0 1 1 1 1 SRP19 protein Fer4_10 PF13237.6 CBK23778.2 - 0.027 14.6 0.8 0.12 12.5 0.1 2.1 2 0 0 2 2 2 0 4Fe-4S dicluster domain RNA_pol_N PF01194.17 CBK23778.2 - 0.035 14.4 2.1 0.066 13.5 2.0 1.5 1 1 0 1 1 1 0 RNA polymerases N / 8 kDa subunit Fer4_2 PF12797.7 CBK23778.2 - 0.048 13.8 3.4 0.14 12.3 1.1 2.2 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4 PF00037.27 CBK23778.2 - 0.085 12.7 3.5 0.11 12.4 0.8 2.1 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_4 PF12800.7 CBK23778.2 - 0.92 10.2 7.3 0.65 10.6 2.6 2.2 2 0 0 2 2 2 0 4Fe-4S binding domain EGF_2 PF07974.13 CBK23779.2 - 0.00046 20.5 6.1 0.00046 20.5 6.1 2.8 2 1 0 2 2 2 1 EGF-like domain Invasin_D3 PF09134.10 CBK23779.2 - 0.004 17.4 0.1 0.011 16.0 0.1 1.8 1 0 0 1 1 1 1 Invasin, domain 3 DUF4064 PF13273.6 CBK23779.2 - 0.032 14.5 1.6 0.071 13.4 0.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4064) SdrG_C_C PF10425.9 CBK23779.2 - 0.081 13.0 0.5 5.2 7.1 0.0 2.2 2 0 0 2 2 2 0 C-terminus of bacterial fibrinogen-binding adhesin Pur_ac_phosph_N PF16656.5 CBK23779.2 - 0.19 12.3 1.3 0.71 10.5 1.3 2.1 1 1 0 1 1 1 0 Purple acid Phosphatase, N-terminal domain SAP30_Sin3_bdg PF13867.6 CBK23780.2 - 1.5e-07 31.7 0.6 3.9e-07 30.3 0.0 1.9 2 0 0 2 2 2 1 Sin3 binding region of histone deacetylase complex subunit SAP30 PHD PF00628.29 CBK23780.2 - 4.3e-07 29.7 12.5 1.2e-06 28.3 12.5 1.7 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.6 CBK23780.2 - 0.095 13.0 10.4 0.17 12.1 10.0 1.7 1 1 0 1 1 1 0 PHD-like zinc-binding domain HJURP_mid PF12346.8 CBK23780.2 - 0.096 13.1 5.3 0.16 12.4 5.0 1.6 1 1 0 1 1 1 0 Holliday junction recognition protein-associated repeat ABC_tran PF00005.27 CBK23781.2 - 5.9e-16 59.2 0.0 8.5e-16 58.7 0.0 1.2 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 CBK23781.2 - 1.1e-05 25.0 0.0 1.4e-05 24.6 0.0 1.1 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 CBK23781.2 - 0.032 14.0 0.0 0.036 13.9 0.0 1.1 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system ABC_ATPase PF09818.9 CBK23781.2 - 0.053 12.3 0.0 0.082 11.7 0.0 1.3 1 1 0 1 1 1 0 Predicted ATPase of the ABC class Thioredoxin PF00085.20 CBK23782.2 - 2.8e-20 72.2 0.1 3.6e-20 71.9 0.1 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_7 PF13899.6 CBK23782.2 - 2.5e-05 24.4 0.0 3.9e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_8 PF13905.6 CBK23782.2 - 0.00029 21.1 0.0 0.00054 20.2 0.0 1.5 2 0 0 2 2 2 1 Thioredoxin-like Thioredoxin_2 PF13098.6 CBK23782.2 - 0.00093 19.6 0.1 0.0031 17.9 0.1 1.8 1 1 0 1 1 1 1 Thioredoxin-like domain AhpC-TSA PF00578.21 CBK23782.2 - 0.0018 18.2 0.0 0.0022 17.9 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family OST3_OST6 PF04756.13 CBK23782.2 - 0.0098 15.3 0.1 0.011 15.2 0.1 1.2 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_3 PF13192.6 CBK23782.2 - 0.049 13.7 0.0 0.071 13.2 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin domain Thioredox_DsbH PF03190.15 CBK23782.2 - 0.054 13.4 0.1 0.072 13.0 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF255 Glutaredoxin PF00462.24 CBK23782.2 - 0.07 13.4 0.0 0.13 12.5 0.0 1.4 1 0 0 1 1 1 0 Glutaredoxin NMD3 PF04981.13 CBK23783.2 - 9.8e-49 166.0 5.1 9.8e-49 166.0 5.1 1.6 2 0 0 2 2 2 1 NMD3 family Yippee-Mis18 PF03226.14 CBK23783.2 - 0.03 14.5 0.1 0.12 12.5 0.1 2.1 1 0 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly zf-RING_7 PF02591.15 CBK23783.2 - 0.075 13.2 2.4 0.48 10.7 0.0 2.8 2 0 0 2 2 2 0 C4-type zinc ribbon domain zf-ribbon_3 PF13248.6 CBK23783.2 - 0.21 11.0 1.2 6.9 6.2 0.1 2.6 2 0 0 2 2 2 0 zinc-ribbon domain Zip PF02535.22 CBK23783.2 - 6.3 5.9 9.6 8.9 5.4 9.6 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Pox_Ag35 PF03286.14 CBK23783.2 - 9.7 5.9 16.5 16 5.2 16.5 1.3 1 0 0 1 1 1 0 Pox virus Ag35 surface protein DNA_pol_B_2 PF03175.13 CBK23784.2 - 1.4e-16 60.4 15.6 5.5e-14 51.9 9.2 2.4 2 0 0 2 2 2 2 DNA polymerase type B, organellar and viral GHMP_kinases_C PF08544.13 CBK23786.2 - 7.9e-09 35.8 0.2 1.5e-08 34.8 0.2 1.5 1 1 0 1 1 1 1 GHMP kinases C terminal CSTF2_hinge PF14327.6 CBK23786.2 - 0.12 12.9 0.0 0.2 12.1 0.0 1.4 1 0 0 1 1 1 0 Hinge domain of cleavage stimulation factor subunit 2 eIF3_N PF09440.10 CBK23787.2 - 3.2e-13 50.3 0.2 1.6e-12 48.0 0.0 2.2 2 1 0 2 2 2 1 eIF3 subunit 6 N terminal domain VID27_PH PF17747.1 CBK23788.2 - 0.0035 17.6 0.2 0.0036 17.6 0.2 1.1 1 0 0 1 1 1 1 VID27 PH-like domain eIF3_N PF09440.10 CBK23788.2 - 0.14 12.6 0.0 0.21 12.0 0.0 1.3 1 0 0 1 1 1 0 eIF3 subunit 6 N terminal domain Rib_5-P_isom_A PF06026.14 CBK23789.2 - 9.7e-62 207.6 0.2 1.2e-61 207.4 0.2 1.1 1 0 0 1 1 1 1 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) DeoRC PF00455.22 CBK23789.2 - 0.0017 18.4 0.2 0.0054 16.7 0.0 1.8 2 0 0 2 2 2 1 DeoR C terminal sensor domain TIM PF00121.18 CBK23790.2 - 2.1e-83 279.5 0.1 3.9e-83 278.6 0.1 1.4 1 0 0 1 1 1 1 Triosephosphate isomerase Gp_dh_C PF02800.20 CBK23790.2 - 2.4e-67 225.5 0.0 1.4e-66 222.9 0.0 2.1 2 0 0 2 2 2 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 CBK23790.2 - 3.1e-34 117.3 0.0 7.7e-34 116.1 0.0 1.7 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain CutC PF03932.14 CBK23790.2 - 0.042 13.3 0.0 0.091 12.2 0.0 1.5 1 0 0 1 1 1 0 CutC family SRPRB PF09439.10 CBK23791.2 - 7.6e-27 93.9 0.0 9.9e-27 93.5 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Arf PF00025.21 CBK23791.2 - 6.7e-09 35.4 0.0 9.6e-09 34.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 CBK23791.2 - 2.5e-06 27.7 0.0 3.8e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Gtr1_RagA PF04670.12 CBK23791.2 - 1.5e-05 24.5 0.0 1.8e-05 24.2 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.20 CBK23791.2 - 0.00069 18.9 0.1 0.43 9.7 0.0 2.1 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.22 CBK23791.2 - 0.0028 17.3 0.0 0.0042 16.7 0.0 1.2 1 0 0 1 1 1 1 Ras family GTP_EFTU PF00009.27 CBK23791.2 - 0.0045 16.6 0.0 0.045 13.3 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain CdiA_C PF18451.1 CBK23791.2 - 0.11 12.7 0.0 0.19 12.0 0.0 1.4 1 0 0 1 1 1 0 Contact-dependent growth inhibition CdiA C-terminal domain SET PF00856.28 CBK23792.2 - 1.4e-05 25.5 0.0 0.25 11.7 0.0 3.0 2 1 0 2 2 2 2 SET domain Rubis-subs-bind PF09273.11 CBK23792.2 - 7.5e-05 23.4 1.0 0.001 19.8 0.0 2.6 2 1 0 2 2 2 1 Rubisco LSMT substrate-binding DUF3658 PF12395.8 CBK23792.2 - 0.31 10.9 3.6 1.8 8.5 0.1 2.8 3 0 0 3 3 3 0 Protein of unknown function DEAD PF00270.29 CBK23793.2 - 2e-30 105.9 0.1 1.8e-27 96.3 0.0 3.6 2 1 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CBK23793.2 - 1.5e-24 86.5 0.2 6.6e-24 84.4 0.0 2.1 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ERCC3_RAD25_C PF16203.5 CBK23793.2 - 0.0004 19.7 0.0 0.00063 19.0 0.0 1.2 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase ResIII PF04851.15 CBK23793.2 - 0.069 13.1 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit DBP10CT PF08147.12 CBK23795.2 - 4.8e-15 55.6 4.3 1.1e-14 54.3 4.3 1.7 1 0 0 1 1 1 1 DBP10CT (NUC160) domain PAD_porph PF04371.15 CBK23796.2 - 7.4e-123 409.9 0.0 8.4e-123 409.7 0.0 1.0 1 0 0 1 1 1 1 Porphyromonas-type peptidyl-arginine deiminase Helicase_C_2 PF13307.6 CBK23797.2 - 7.2e-38 130.4 0.0 1e-37 130.0 0.0 1.2 1 0 0 1 1 1 1 Helicase C-terminal domain DEAD_2 PF06733.15 CBK23798.2 - 2.4e-20 72.9 0.1 3.5e-20 72.4 0.1 1.2 1 0 0 1 1 1 1 DEAD_2 Hormone_1 PF00103.20 CBK23798.2 - 0.005 16.6 0.1 0.007 16.1 0.1 1.2 1 0 0 1 1 1 1 Somatotropin hormone family YAF2_RYBP PF17219.3 CBK23798.2 - 0.17 11.5 0.0 0.34 10.5 0.0 1.5 1 0 0 1 1 1 0 Yaf2/RYBP C-terminal binding motif DEAD_2 PF06733.15 CBK23799.2 - 2.6e-10 40.2 2.4 2.6e-10 40.2 2.4 1.8 2 0 0 2 2 2 1 DEAD_2 ResIII PF04851.15 CBK23799.2 - 1.2e-07 31.9 0.0 1.5e-07 31.6 0.0 1.1 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 CBK23799.2 - 0.0007 19.4 0.0 0.00082 19.2 0.0 1.1 1 0 0 1 1 1 1 DEAD/DEAH box helicase T2SSE PF00437.20 CBK23799.2 - 0.02 14.0 0.0 0.025 13.6 0.0 1.1 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_11 PF13086.6 CBK23799.2 - 0.049 13.4 0.0 0.056 13.2 0.0 1.1 1 0 0 1 1 1 0 AAA domain T6PP_N PF18572.1 CBK23799.2 - 0.072 12.9 0.0 0.29 11.0 0.0 1.8 1 1 0 1 1 1 0 Trehalose-6-phosphate phosphatase N-terminal helical bundle domain DAGK_acc PF00609.19 CBK23800.2 - 2.5e-25 89.7 0.0 3.3e-25 89.3 0.0 1.2 1 0 0 1 1 1 1 Diacylglycerol kinase accessory domain Leo1 PF04004.13 CBK23801.2 - 7.4e-17 61.7 1.4 1.3e-16 60.9 1.4 1.4 1 0 0 1 1 1 1 Leo1-like protein FAM110_C PF14160.6 CBK23801.2 - 0.84 10.7 4.0 0.29 12.2 0.2 2.3 2 2 1 3 3 3 0 Centrosome-associated C terminus Ank_4 PF13637.6 CBK23802.2 - 1.5e-12 47.7 1.3 4.4e-07 30.3 0.1 4.1 2 2 2 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 CBK23802.2 - 2.4e-09 36.6 1.8 0.2 12.3 0.1 5.5 5 0 0 5 5 5 2 Ankyrin repeat Ank_2 PF12796.7 CBK23802.2 - 2.2e-07 31.4 3.4 0.0099 16.4 0.2 3.2 3 1 1 4 4 4 2 Ankyrin repeats (3 copies) Ank PF00023.30 CBK23802.2 - 0.00031 21.1 3.6 52 4.5 0.1 5.4 5 0 0 5 5 5 0 Ankyrin repeat Glyco_hydro_36C PF16874.5 CBK23802.2 - 0.016 15.7 0.0 0.29 11.7 0.0 2.7 3 0 0 3 3 3 0 Glycosyl hydrolase family 36 C-terminal domain Ank_5 PF13857.6 CBK23802.2 - 0.063 13.6 1.5 0.35 11.3 0.1 3.0 4 0 0 4 4 4 0 Ankyrin repeats (many copies) fn3 PF00041.21 CBK23802.2 - 0.066 13.6 0.0 0.14 12.5 0.0 1.5 1 0 0 1 1 1 0 Fibronectin type III domain DNA_pol_B_2 PF03175.13 CBK23803.2 - 4.3e-16 58.8 13.6 2e-13 50.0 7.6 2.3 2 0 0 2 2 2 2 DNA polymerase type B, organellar and viral MyTH4 PF00784.17 CBK23804.2 - 1.9e-14 54.0 0.5 4.8e-14 52.8 0.5 1.7 1 0 0 1 1 1 1 MyTH4 domain WW PF00397.26 CBK23804.2 - 1.8e-06 27.9 0.0 3.9e-06 26.8 0.0 1.6 1 0 0 1 1 1 1 WW domain RA PF00788.23 CBK23804.2 - 0.014 16.0 0.4 0.041 14.5 0.0 2.0 2 0 0 2 2 2 0 Ras association (RalGDS/AF-6) domain IRS PF02174.17 CBK23804.2 - 0.041 13.8 0.0 0.12 12.3 0.0 1.8 1 0 0 1 1 1 0 PTB domain (IRS-1 type) FERM_M PF00373.18 CBK23804.2 - 0.051 14.0 0.9 1.7 9.0 0.0 2.7 1 1 1 2 2 2 0 FERM central domain CYYR1 PF10873.8 CBK23805.2 - 0.057 13.9 1.4 0.22 12.0 0.2 2.2 2 0 0 2 2 2 0 Cysteine and tyrosine-rich protein 1 DUF2944 PF11161.8 CBK23805.2 - 0.13 12.1 0.0 0.33 10.8 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2946) Aa_trans PF01490.18 CBK23806.2 - 6.8e-06 25.0 2.6 7.7e-06 24.9 2.6 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Cytochrom_B_C PF00032.17 CBK23806.2 - 0.014 15.7 0.9 0.018 15.3 0.9 1.1 1 0 0 1 1 1 0 Cytochrome b(C-terminal)/b6/petD DUF3021 PF11457.8 CBK23806.2 - 0.022 15.1 3.8 0.027 14.8 3.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3021) Peptidase_M41 PF01434.18 CBK23808.2 - 7.8e-56 188.9 0.1 1.8e-55 187.8 0.1 1.6 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 CBK23808.2 - 1.7e-40 138.5 0.0 6.6e-40 136.6 0.0 2.1 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Peptidase_M16_C PF05193.21 CBK23808.2 - 3.8e-14 53.1 0.9 6.3e-14 52.4 0.1 1.9 2 0 0 2 2 2 1 Peptidase M16 inactive domain AAA_lid_3 PF17862.1 CBK23808.2 - 6.1e-12 45.1 0.0 2.3e-11 43.3 0.0 2.0 1 0 0 1 1 1 1 AAA+ lid domain Peptidase_M16 PF00675.20 CBK23808.2 - 9.6e-08 32.1 0.0 3.6e-07 30.3 0.0 2.0 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) AAA_5 PF07728.14 CBK23808.2 - 0.002 18.2 0.0 0.0066 16.5 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) TIP49 PF06068.13 CBK23808.2 - 0.016 14.5 0.2 0.039 13.1 0.2 1.6 1 1 0 1 1 1 0 TIP49 P-loop domain AAA_16 PF13191.6 CBK23808.2 - 0.017 15.5 0.1 0.32 11.4 0.1 2.5 1 1 1 2 2 2 0 AAA ATPase domain AAA_22 PF13401.6 CBK23808.2 - 0.02 15.2 0.1 0.27 11.5 0.0 2.5 1 1 1 2 2 2 0 AAA domain RuvB_N PF05496.12 CBK23808.2 - 0.023 14.5 0.0 0.051 13.3 0.0 1.6 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 CBK23808.2 - 0.035 14.2 0.0 0.035 14.2 0.0 2.8 3 0 0 3 3 2 0 AAA domain (Cdc48 subfamily) Pox_Ag35 PF03286.14 CBK23808.2 - 0.11 12.3 10.0 0.2 11.4 10.0 1.3 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Connexin PF00029.19 CBK23808.2 - 0.11 12.3 2.9 0.2 11.4 2.9 1.4 1 0 0 1 1 1 0 Connexin IstB_IS21 PF01695.17 CBK23808.2 - 0.15 11.8 0.0 0.33 10.6 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_11 PF13086.6 CBK23808.2 - 0.18 11.5 10.0 6.9 6.4 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 CBK23808.2 - 0.53 10.8 0.0 0.53 10.8 0.0 3.8 5 1 0 5 5 4 0 AAA domain Slu7 PF11708.8 CBK23808.2 - 1.4 8.6 12.4 27 4.4 12.2 2.3 2 0 0 2 2 2 0 Pre-mRNA splicing Prp18-interacting factor RNA_polI_A34 PF08208.11 CBK23808.2 - 6.8 6.7 19.3 12 5.9 19.3 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 Vfa1 PF08432.10 CBK23808.2 - 7.1 6.9 15.2 10 6.4 13.4 2.1 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 Pantoate_transf PF02548.15 CBK23810.2 - 1.7e-101 339.0 0.0 2.4e-101 338.5 0.0 1.2 1 0 0 1 1 1 1 Ketopantoate hydroxymethyltransferase NanE PF04131.14 CBK23810.2 - 0.0021 17.3 0.0 0.072 12.3 0.0 2.4 2 0 0 2 2 2 2 Putative N-acetylmannosamine-6-phosphate epimerase ETC_C1_NDUFA4 PF04800.12 CBK23811.2 - 5.3e-08 33.0 0.0 9e-08 32.3 0.0 1.3 1 0 0 1 1 1 1 ETC complex I subunit conserved region RabGAP-TBC PF00566.18 CBK23812.2 - 2e-36 125.6 0.0 2.1e-35 122.3 0.0 2.0 1 1 0 1 1 1 1 Rab-GTPase-TBC domain RCC1 PF00415.18 CBK23812.2 - 5.5e-36 123.0 2.4 2.7e-13 50.3 0.0 5.4 5 0 0 5 5 5 4 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 CBK23812.2 - 1.4e-27 94.9 17.1 2.6e-09 36.6 0.5 5.4 5 0 0 5 5 5 5 Regulator of chromosome condensation (RCC1) repeat Proton_antipo_M PF00361.20 CBK23813.2 - 5.2e-73 245.8 34.2 5.2e-73 245.8 34.2 2.5 2 2 0 2 2 2 1 Proton-conducting membrane transporter Oxidored_q5_N PF01059.17 CBK23813.2 - 0.0034 17.5 22.7 0.0034 17.5 22.7 5.9 4 1 0 5 5 5 1 NADH-ubiquinone oxidoreductase chain 4, amino terminus Complex1_49kDa PF00346.19 CBK23814.2 - 6.7e-118 392.7 0.0 8.3e-118 392.4 0.0 1.1 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 49 Kd subunit NiFeSe_Hases PF00374.19 CBK23814.2 - 0.0084 15.0 0.0 0.014 14.4 0.0 1.3 1 0 0 1 1 1 1 Nickel-dependent hydrogenase Oxidored_q3 PF00499.20 CBK23815.2 - 1.3e-28 99.5 28.0 1.7e-28 99.2 28.0 1.1 1 0 0 1 1 1 1 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 Phage_holin_3_6 PF07332.11 CBK23815.2 - 0.39 10.8 10.6 5.6 7.0 8.4 2.4 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III Oxidored_q4 PF00507.19 CBK23816.2 - 9.9e-35 118.7 6.3 9.9e-35 118.7 6.3 1.3 1 1 0 1 1 1 1 NADH-ubiquinone/plastoquinone oxidoreductase, chain 3 Ribosom_S12_S23 PF00164.25 CBK23817.2 - 1.2e-31 108.6 2.7 1.6e-31 108.3 2.7 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 GAIN_A PF18619.1 CBK23817.2 - 0.3 11.3 3.6 7.2 6.9 0.0 2.7 2 1 1 3 3 3 0 GPCR-Autoproteolysis-INducing (GAIN) subdomain A Oxidored_q2 PF00420.24 CBK23818.2 - 1.4e-16 60.0 10.4 1.6e-16 59.8 10.4 1.0 1 0 0 1 1 1 1 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L NADHdh PF00146.21 CBK23819.2 - 1.2e-114 382.7 25.0 1.4e-114 382.5 25.0 1.0 1 0 0 1 1 1 1 NADH dehydrogenase PSI_PsaJ PF01701.18 CBK23819.2 - 0.31 11.6 8.2 0.48 11.0 1.2 3.8 3 0 0 3 3 3 0 Photosystem I reaction centre subunit IX / PsaJ DUF2755 PF10954.8 CBK23819.2 - 0.48 10.4 4.4 1.5 8.8 0.1 3.1 2 1 0 2 2 2 0 Protein of unknown function (DUF2755) Molybdopterin PF00384.22 CBK23820.2 - 2.1e-23 83.0 0.2 6.3e-18 64.9 0.0 2.5 2 1 0 2 2 2 2 Molybdopterin oxidoreductase NADH-G_4Fe-4S_3 PF10588.9 CBK23820.2 - 2.5e-17 62.1 0.2 2.5e-17 62.1 0.2 2.2 3 0 0 3 3 3 1 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region NADH_dhqG_C PF09326.11 CBK23820.2 - 0.0021 18.7 0.1 0.0044 17.7 0.1 1.5 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase subunit G, C-terminal Fer2 PF00111.27 CBK23820.2 - 0.0025 17.7 0.8 0.012 15.5 0.0 2.1 1 1 1 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fer2_4 PF13510.6 CBK23820.2 - 0.17 11.9 0.0 0.36 10.9 0.0 1.5 1 0 0 1 1 1 0 2Fe-2S iron-sulfur cluster binding domain Fer4_17 PF13534.6 CBK23820.2 - 1.4 9.5 6.5 0.71 10.5 2.9 2.4 3 0 0 3 3 3 0 4Fe-4S dicluster domain Fer4_7 PF12838.7 CBK23820.2 - 4.6 7.9 6.0 46 4.7 5.0 2.9 2 1 0 2 2 2 0 4Fe-4S dicluster domain Proton_antipo_M PF00361.20 CBK23821.2 - 2.6e-55 187.7 34.2 2.6e-55 187.7 34.2 2.4 2 0 0 2 2 2 1 Proton-conducting membrane transporter Complex1_30kDa PF00329.19 CBK23822.2 - 1.6e-38 132.0 0.0 2.4e-38 131.5 0.0 1.3 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 30 Kd subunit Proton_antipo_M PF00361.20 CBK23823.2 - 8.6e-82 274.6 24.9 8.6e-82 274.6 24.9 2.6 2 0 0 2 2 2 1 Proton-conducting membrane transporter Proton_antipo_N PF00662.20 CBK23823.2 - 1.1e-19 70.3 6.0 1.1e-19 70.3 6.0 4.0 3 0 0 3 3 3 1 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus NADH5_C PF06455.11 CBK23823.2 - 5.8e-14 52.1 39.2 1.8e-13 50.5 11.7 5.6 3 3 1 4 4 4 2 NADH dehydrogenase subunit 5 C-terminus Ribosomal_L14 PF00238.19 CBK23824.2 - 7.1e-20 71.3 2.2 7.9e-20 71.2 2.2 1.1 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e E1_DerP2_DerF2 PF02221.15 CBK23827.2 - 2e-13 50.9 0.1 2.3e-13 50.8 0.1 1.0 1 0 0 1 1 1 1 ML domain DIM PF08194.12 CBK23827.2 - 0.55 10.5 2.8 1.9 8.8 0.1 2.5 2 1 0 2 2 2 0 DIM protein WD40 PF00400.32 CBK23828.2 - 3.4e-12 46.7 11.4 0.021 15.7 0.3 5.8 5 1 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBK23828.2 - 5e-07 29.9 3.6 0.13 12.5 0.0 4.0 2 2 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain DUF563 PF04577.14 CBK23831.2 - 2.3e-19 70.3 1.3 4.1e-19 69.6 1.3 1.5 1 1 1 2 2 2 1 Protein of unknown function (DUF563) Glyco_transf_49 PF13896.6 CBK23832.2 - 2.2e-12 47.0 1.3 2.9e-07 30.1 0.2 2.4 1 1 0 2 2 2 2 Glycosyl-transferase for dystroglycan PyrI_C PF02748.15 CBK23832.2 - 0.17 11.8 3.8 0.12 12.3 0.9 2.2 2 0 0 2 2 2 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain Ribosomal_L7Ae PF01248.26 CBK23834.2 - 0.0034 17.1 0.0 0.0062 16.2 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Cas9_C PF18525.1 CBK23834.2 - 0.14 12.3 0.0 0.2 11.9 0.0 1.1 1 0 0 1 1 1 0 Cas9 C-terminal domain Glyco_transf_49 PF13896.6 CBK23836.2 - 2.4e-09 37.0 2.7 9.2e-09 35.1 0.3 2.4 2 1 0 2 2 2 1 Glycosyl-transferase for dystroglycan FBA_1 PF07734.13 CBK23836.2 - 0.00063 19.7 0.5 0.0016 18.4 0.4 1.7 1 1 0 1 1 1 1 F-box associated OSK PF17182.4 CBK23836.2 - 0.021 14.1 1.4 0.025 13.8 0.2 1.7 2 0 0 2 2 2 0 OSK domain Glyco_hydro_35 PF01301.19 CBK23838.2 - 4.4e-19 69.2 0.0 5.1e-19 69.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 Glyco_hydro_42 PF02449.15 CBK23838.2 - 0.053 12.9 0.0 0.061 12.6 0.0 1.1 1 0 0 1 1 1 0 Beta-galactosidase Glyco_hydro_35 PF01301.19 CBK23839.2 - 3e-37 129.0 3.0 4.7e-37 128.3 3.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 BetaGal_dom4_5 PF13364.6 CBK23839.2 - 1.7e-08 35.0 2.5 2.7e-05 24.7 0.1 3.4 3 0 0 3 3 3 2 Beta-galactosidase jelly roll domain GHD PF17834.1 CBK23839.2 - 4.1e-05 23.5 0.4 8.7e-05 22.5 0.4 1.5 1 0 0 1 1 1 1 Beta-sandwich domain in beta galactosidase RabGAP-TBC PF00566.18 CBK23840.2 - 2.3e-13 50.3 1.9 2.3e-13 50.3 1.9 1.5 2 0 0 2 2 2 1 Rab-GTPase-TBC domain Ribosomal_S4Pg PF11993.8 CBK23840.2 - 0.0084 16.2 0.0 0.011 15.8 0.0 1.2 1 0 0 1 1 1 1 Ribosomal S4P (gammaproteobacterial) RabGAP-TBC PF00566.18 CBK23841.2 - 1.9e-25 89.8 0.0 4e-25 88.8 0.0 1.6 1 1 0 1 1 1 1 Rab-GTPase-TBC domain TraH PF06122.11 CBK23841.2 - 0.049 12.9 0.0 0.064 12.5 0.0 1.1 1 0 0 1 1 1 0 Conjugative relaxosome accessory transposon protein Glyco_hydro_77 PF02446.17 CBK23842.2 - 0.057 12.3 0.0 0.066 12.1 0.0 1.0 1 0 0 1 1 1 0 4-alpha-glucanotransferase DUF4090 PF13319.6 CBK23843.2 - 0.053 13.8 1.0 0.067 13.5 1.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4090) IATP PF04568.12 CBK23843.2 - 0.16 12.4 5.6 0.26 11.7 5.6 1.5 1 1 0 1 1 1 0 Mitochondrial ATPase inhibitor, IATP ACBP PF00887.19 CBK23844.2 - 8.6e-29 99.6 0.4 1e-28 99.4 0.4 1.0 1 0 0 1 1 1 1 Acyl CoA binding protein FERM_M PF00373.18 CBK23844.2 - 0.14 12.6 0.1 0.25 11.8 0.1 1.3 1 1 0 1 1 1 0 FERM central domain TRIC PF05197.13 CBK23845.2 - 3.8e-09 36.4 1.2 5.5e-09 35.9 1.2 1.3 1 0 0 1 1 1 1 TRIC channel UPF0126 PF03458.13 CBK23845.2 - 2e-05 24.4 4.0 0.0019 18.1 0.3 2.2 2 0 0 2 2 2 2 UPF0126 domain Imm42 PF15593.6 CBK23846.2 - 0.0097 16.4 1.3 0.017 15.6 1.3 1.4 1 0 0 1 1 1 1 Immunity protein 42 WDCP PF15390.6 CBK23846.2 - 0.014 13.8 2.1 0.017 13.6 2.1 1.1 1 0 0 1 1 1 0 WD repeat and coiled-coil-containing protein family SNAP PF14938.6 CBK23847.2 - 9.5e-103 343.5 17.9 1.1e-102 343.3 17.9 1.0 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_12 PF13424.6 CBK23847.2 - 2.7e-13 50.0 10.2 7.4e-06 26.2 0.6 4.1 2 2 1 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 CBK23847.2 - 1.7e-10 40.1 7.4 0.22 11.6 0.0 6.5 4 1 2 6 6 6 3 Tetratricopeptide repeat TPR_1 PF00515.28 CBK23847.2 - 3.9e-08 32.8 18.8 0.014 15.2 0.1 5.9 4 1 3 7 7 6 3 Tetratricopeptide repeat TPR_2 PF07719.17 CBK23847.2 - 9.1e-08 31.6 17.5 0.43 10.8 0.0 6.0 3 1 3 6 6 6 3 Tetratricopeptide repeat TPR_14 PF13428.6 CBK23847.2 - 1.4e-07 31.8 2.0 7.4 7.7 0.1 5.3 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_6 PF13174.6 CBK23847.2 - 6.4e-07 29.6 11.9 0.45 11.3 0.5 5.4 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.6 CBK23847.2 - 3.3e-05 23.8 16.0 0.34 11.2 0.2 5.7 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_19 PF14559.6 CBK23847.2 - 6.2e-05 23.4 7.9 0.018 15.6 0.4 3.7 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_10 PF13374.6 CBK23847.2 - 0.00012 21.8 9.5 1.9 8.5 0.1 5.3 3 1 3 6 6 6 2 Tetratricopeptide repeat DHR-2 PF06920.13 CBK23847.2 - 0.00016 20.4 6.9 0.0084 14.8 1.3 2.7 1 1 2 3 3 3 2 Dock homology region 2 PPR PF01535.20 CBK23847.2 - 0.0007 19.7 7.0 4.4 7.8 0.1 4.5 3 1 1 4 4 4 2 PPR repeat Sel1 PF08238.12 CBK23847.2 - 0.0012 19.4 1.5 20 6.0 0.3 3.8 3 0 0 3 3 3 0 Sel1 repeat ANAPC3 PF12895.7 CBK23847.2 - 0.0018 18.5 8.9 0.15 12.3 0.4 3.2 1 1 0 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_MalT PF17874.1 CBK23847.2 - 0.018 14.4 3.6 0.041 13.2 2.9 1.7 1 1 1 2 2 2 0 MalT-like TPR region TPR_11 PF13414.6 CBK23847.2 - 0.039 13.7 14.5 2.8 7.7 0.0 5.7 5 1 2 7 7 7 0 TPR repeat TPR_16 PF13432.6 CBK23847.2 - 0.068 13.8 8.8 0.7 10.6 1.6 3.9 2 2 0 2 2 2 0 Tetratricopeptide repeat Clathrin PF00637.20 CBK23847.2 - 0.079 12.8 5.9 0.44 10.4 2.1 3.2 1 1 1 2 2 2 0 Region in Clathrin and VPS RPN7 PF10602.9 CBK23847.2 - 0.13 12.0 11.2 0.64 9.7 0.1 3.9 1 1 4 5 5 5 0 26S proteasome subunit RPN7 MIT PF04212.18 CBK23847.2 - 0.24 11.5 16.2 3.3 7.8 0.8 4.5 4 0 0 4 4 4 0 MIT (microtubule interacting and transport) domain PPR_1 PF12854.7 CBK23847.2 - 0.38 10.5 4.3 45 3.9 0.1 3.5 2 1 1 3 3 3 0 PPR repeat PPR_2 PF13041.6 CBK23847.2 - 0.39 10.9 8.1 10 6.4 0.1 4.0 3 1 1 4 4 4 0 PPR repeat family NRBF2_MIT PF17169.4 CBK23847.2 - 0.75 10.1 8.7 16 5.8 0.3 3.7 1 1 2 4 4 4 0 MIT domain of nuclear receptor-binding factor 2 PTS_IIA PF02255.16 CBK23847.2 - 3.9 7.6 6.4 22 5.2 0.2 3.2 3 1 0 3 3 3 0 PTS system, Lactose/Cellobiose specific IIA subunit vATP-synt_E PF01991.18 CBK23848.2 - 2.4e-49 167.4 5.1 3e-49 167.2 5.1 1.1 1 0 0 1 1 1 1 ATP synthase (E/31 kDa) subunit Folliculin PF11704.8 CBK23848.2 - 2.2 8.2 5.4 2.8 7.8 5.4 1.2 1 0 0 1 1 1 0 Vesicle coat protein involved in Golgi to plasma membrane transport YtxH PF12732.7 CBK23848.2 - 3.8 8.1 5.2 35 5.0 5.2 2.2 1 1 0 1 1 1 0 YtxH-like protein Pkinase PF00069.25 CBK23849.2 - 1.9e-27 96.3 0.0 2.2e-27 96.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBK23849.2 - 8.7e-17 61.2 0.0 1.1e-16 60.9 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CBK23849.2 - 0.00095 18.6 0.0 0.0013 18.1 0.0 1.2 1 1 0 1 1 1 1 Kinase-like APH PF01636.23 CBK23849.2 - 0.1 12.5 0.0 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 CBK23849.2 - 0.14 10.9 0.0 0.17 10.6 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase Pkinase PF00069.25 CBK23850.2 - 1.4e-71 240.9 0.0 1.8e-71 240.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBK23850.2 - 6.1e-28 97.8 0.0 7.8e-28 97.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 CBK23850.2 - 6.7e-05 22.0 0.0 0.00042 19.4 0.0 2.0 1 1 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 CBK23850.2 - 0.0049 16.8 0.0 0.0071 16.3 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 CBK23850.2 - 0.0058 16.0 0.0 0.1 11.9 0.0 2.2 2 0 0 2 2 2 1 Kinase-like Rad51 PF08423.11 CBK23852.2 - 2.4e-121 403.8 0.0 3.4e-121 403.3 0.0 1.2 1 0 0 1 1 1 1 Rad51 RecA PF00154.21 CBK23852.2 - 3.5e-12 46.3 0.1 5.4e-12 45.7 0.1 1.3 1 0 0 1 1 1 1 recA bacterial DNA recombination protein AAA_25 PF13481.6 CBK23852.2 - 1.8e-08 34.2 0.0 2.8e-08 33.6 0.0 1.2 1 0 0 1 1 1 1 AAA domain ATPase PF06745.13 CBK23852.2 - 3.8e-06 26.4 0.0 7.9e-06 25.4 0.0 1.6 1 1 0 1 1 1 1 KaiC DnaB_C PF03796.15 CBK23852.2 - 3.3e-05 23.3 0.0 0.0038 16.6 0.0 2.3 2 0 0 2 2 2 2 DnaB-like helicase C terminal domain HHH_5 PF14520.6 CBK23852.2 - 5e-05 23.8 1.0 0.00011 22.7 1.0 1.5 1 0 0 1 1 1 1 Helix-hairpin-helix domain AAA_24 PF13479.6 CBK23852.2 - 0.00021 21.1 0.0 0.0004 20.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain PAXNEB PF05625.11 CBK23852.2 - 0.0041 16.3 0.1 0.026 13.7 0.0 2.0 2 0 0 2 2 2 1 PAXNEB protein LpxC PF03331.13 CBK23852.2 - 0.081 12.4 0.0 0.15 11.6 0.0 1.4 1 0 0 1 1 1 0 UDP-3-O-acyl N-acetylglycosamine deacetylase AAA PF00004.29 CBK23852.2 - 0.13 12.7 0.0 0.76 10.2 0.0 2.2 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) POR_N PF01855.19 CBK23853.2 - 2.4e-58 197.6 0.1 4.4e-58 196.8 0.1 1.4 1 0 0 1 1 1 1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg POR PF01558.18 CBK23853.2 - 1.3e-28 100.3 0.3 3.3e-28 98.9 0.3 1.7 1 0 0 1 1 1 1 Pyruvate ferredoxin/flavodoxin oxidoreductase PFOR_II PF17147.4 CBK23853.2 - 6.1e-13 49.0 0.0 1.9e-12 47.4 0.0 1.9 1 0 0 1 1 1 1 Pyruvate:ferredoxin oxidoreductase core domain II EKR PF10371.9 CBK23853.2 - 1.5e-09 37.5 0.0 5e-09 35.8 0.0 1.9 1 0 0 1 1 1 1 Domain of unknown function Fer4_7 PF12838.7 CBK23853.2 - 7.2e-09 36.1 7.0 7.2e-09 36.1 7.0 2.2 2 0 0 2 2 1 1 4Fe-4S dicluster domain Fer4_16 PF13484.6 CBK23853.2 - 9e-09 36.1 15.5 1.2e-07 32.5 6.4 2.6 1 1 1 2 2 2 2 4Fe-4S double cluster binding domain TPP_enzyme_C PF02775.21 CBK23853.2 - 2.1e-08 34.1 0.4 7.1e-08 32.4 0.4 1.9 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Fer4_10 PF13237.6 CBK23853.2 - 9.1e-08 32.1 7.7 0.0024 18.0 0.9 2.7 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4 PF00037.27 CBK23853.2 - 3e-07 30.0 18.9 0.00013 21.6 1.4 3.0 3 0 0 3 3 3 2 4Fe-4S binding domain Fer4_9 PF13187.6 CBK23853.2 - 6.1e-07 29.5 19.0 3e-06 27.3 8.4 2.5 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_6 PF12837.7 CBK23853.2 - 4.2e-05 23.4 19.4 0.0023 17.9 3.0 3.0 3 0 0 3 3 3 2 4Fe-4S binding domain Fer4_21 PF14697.6 CBK23853.2 - 8.4e-05 22.6 15.3 0.0026 17.8 15.3 2.9 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_8 PF13183.6 CBK23853.2 - 0.0001 22.7 6.6 0.0001 22.7 6.6 2.2 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_2 PF12797.7 CBK23853.2 - 0.00016 21.5 19.3 0.0068 16.4 3.5 3.2 3 0 0 3 3 3 2 4Fe-4S binding domain Fer4_17 PF13534.6 CBK23853.2 - 0.0029 18.1 12.4 0.012 16.2 11.1 2.6 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_13 PF13370.6 CBK23853.2 - 0.044 14.3 11.0 0.62 10.7 1.2 3.1 2 0 0 2 2 2 0 4Fe-4S single cluster domain of Ferredoxin I Fer4_18 PF13746.6 CBK23853.2 - 0.071 13.3 11.7 0.47 10.7 9.4 2.7 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_4 PF12800.7 CBK23853.2 - 0.34 11.5 18.9 0.042 14.4 3.5 3.0 3 0 0 3 3 2 0 4Fe-4S binding domain Fer4_3 PF12798.7 CBK23853.2 - 1.9 9.6 22.2 1.3 10.1 6.6 2.8 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_15 PF13459.6 CBK23853.2 - 2 9.2 8.2 14 6.5 0.7 2.9 2 0 0 2 2 2 0 4Fe-4S single cluster domain Ribosomal_L22 PF00237.19 CBK23855.2 - 3.7e-33 113.8 0.2 6.1e-33 113.1 0.2 1.3 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e HORMA PF02301.18 CBK23857.2 - 5e-56 189.6 0.1 8.7e-56 188.9 0.0 1.4 2 0 0 2 2 2 1 HORMA domain CmlA_N PF18456.1 CBK23857.2 - 0.0065 15.8 0.1 0.013 14.8 0.1 1.4 1 0 0 1 1 1 1 Diiron non-heme beta-hydroxylase N-terminal domain Ribosomal_L16 PF00252.18 CBK23858.2 - 6.7e-41 139.4 0.2 9.4e-41 138.9 0.2 1.2 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e Malate_DH PF12434.8 CBK23858.2 - 0.19 11.8 0.0 0.19 11.8 0.0 1.7 2 0 0 2 2 2 0 Malate dehydrogenase enzyme zf-CCHC PF00098.23 CBK23859.2 - 3.8e-55 181.6 62.1 2.2e-09 37.0 3.1 7.1 7 0 0 7 7 7 7 Zinc knuckle zf-CCHC_2 PF13696.6 CBK23859.2 - 8e-17 60.7 65.0 8.3e-05 22.3 3.6 7.3 7 0 0 7 7 7 7 Zinc knuckle zf-CCHC_3 PF13917.6 CBK23859.2 - 9.4e-13 47.9 37.3 0.035 14.1 0.3 7.1 1 1 6 7 7 7 7 Zinc knuckle zf-CCHC_4 PF14392.6 CBK23859.2 - 1.5e-09 37.5 42.9 0.03 14.1 0.7 7.1 7 0 0 7 7 7 7 Zinc knuckle zf-CCHC_5 PF14787.6 CBK23859.2 - 2.7e-05 23.8 53.0 0.016 14.9 1.6 7.1 5 1 2 7 7 7 7 GAG-polyprotein viral zinc-finger zf-CCHC_6 PF15288.6 CBK23859.2 - 0.00024 20.9 53.9 0.0023 17.7 1.4 7.1 4 2 3 7 7 7 4 Zinc knuckle TRAF6_Z2 PF18048.1 CBK23859.2 - 0.6 10.3 29.7 5.2 7.3 0.7 7.0 6 1 1 7 7 7 0 TNF receptor-associated factor 6 zinc finger 2 NAC PF01849.18 CBK23861.2 - 1.4e-14 53.7 0.6 5.3e-14 51.9 0.1 2.0 2 0 0 2 2 2 1 NAC domain UBA_4 PF14555.6 CBK23861.2 - 0.0086 15.9 0.0 0.04 13.7 0.0 2.1 2 0 0 2 2 2 1 UBA-like domain Peptidase_S49_N PF08496.10 CBK23861.2 - 0.016 15.3 0.1 0.029 14.4 0.1 1.5 1 0 0 1 1 1 0 Peptidase family S49 N-terminal DUF3408 PF11888.8 CBK23861.2 - 2.4 8.3 12.0 5.1 7.2 1.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3408) CT47 PF15623.6 CBK23861.2 - 4 7.2 23.2 0.028 14.3 9.2 2.1 2 0 0 2 2 2 0 Cancer/testis gene family 47 N-SET PF11764.8 CBK23861.2 - 4.9 7.2 6.7 3.4 7.7 2.8 2.3 1 1 1 2 2 2 0 COMPASS (Complex proteins associated with Set1p) component N DUF3391 PF11871.8 CBK23861.2 - 5.7 7.5 7.6 0.68 10.5 0.7 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3391) CbtA PF09490.10 CBK23861.2 - 9.7 5.9 11.4 0.46 10.2 2.1 2.2 2 0 0 2 2 2 0 Probable cobalt transporter subunit (CbtA) Brix PF04427.18 CBK23862.2 - 2.9e-38 131.9 0.0 3.9e-38 131.5 0.0 1.2 1 0 0 1 1 1 1 Brix domain DUF382 PF04037.13 CBK23863.2 - 7.4e-52 174.8 0.0 1.5e-51 173.8 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF382) PSP PF04046.16 CBK23863.2 - 5.4e-19 67.8 7.0 9.9e-19 66.9 7.0 1.5 1 0 0 1 1 1 1 PSP Di19_C PF14571.6 CBK23863.2 - 0.2 12.2 0.4 0.48 11.0 0.0 1.8 2 0 0 2 2 2 0 Stress-induced protein Di19, C-terminal Adaptin_N PF01602.20 CBK23864.2 - 1.2e-113 380.5 3.3 1.5e-113 380.2 3.3 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptinC2 PF02883.20 CBK23864.2 - 2.6e-17 63.1 0.0 5.2e-17 62.1 0.0 1.6 1 0 0 1 1 1 1 Adaptin C-terminal domain Cnd1 PF12717.7 CBK23864.2 - 1.2e-07 32.0 5.6 0.00015 21.8 0.3 2.7 3 0 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 DUF4611 PF15387.6 CBK23864.2 - 0.26 11.5 2.4 1.2 9.4 2.4 2.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) V-SNARE_C PF12352.8 CBK23865.2 - 2.2e-07 31.0 4.3 3.5e-07 30.4 1.3 2.1 2 0 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus DUF5345 PF17280.2 CBK23865.2 - 0.092 12.7 0.0 0.21 11.6 0.0 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5345) Cyclin PF08613.11 CBK23866.2 - 1.9e-34 119.4 0.2 2.5e-34 119.0 0.2 1.2 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 CBK23866.2 - 3.6e-11 42.9 0.0 5.2e-11 42.4 0.0 1.2 1 0 0 1 1 1 1 Cyclin, N-terminal domain ELO PF01151.18 CBK23867.2 - 9.5e-49 166.2 28.9 1.1e-48 165.9 28.9 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family C2 PF00168.30 CBK23868.2 - 9.2e-07 29.1 0.1 1.2e-06 28.7 0.1 1.2 1 0 0 1 1 1 1 C2 domain Copine PF07002.16 CBK23869.2 - 9e-64 214.9 0.0 1.3e-63 214.4 0.0 1.2 1 0 0 1 1 1 1 Copine vWA-TerF-like PF10138.9 CBK23869.2 - 7.6e-05 22.9 0.0 0.00021 21.5 0.0 1.7 2 0 0 2 2 2 1 vWA found in TerF C terminus ATP-synt_F PF01990.17 CBK23870.2 - 1.1e-29 102.6 1.9 1.3e-29 102.4 1.9 1.1 1 0 0 1 1 1 1 ATP synthase (F/14-kDa) subunit HTH_50 PF18024.1 CBK23870.2 - 0.13 11.9 0.0 17 5.1 0.0 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain Lipase_3 PF01764.25 CBK23871.2 - 5.7e-06 26.3 0.0 1.3e-05 25.1 0.0 1.7 2 0 0 2 2 2 1 Lipase (class 3) Abhydrolase_6 PF12697.7 CBK23871.2 - 0.0015 19.1 0.1 0.0019 18.8 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF2974 PF11187.8 CBK23871.2 - 0.06 12.9 0.0 0.086 12.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Hydrolase_4 PF12146.8 CBK23871.2 - 0.12 11.6 0.0 2.6 7.2 0.0 2.1 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Arf PF00025.21 CBK23872.2 - 2.2e-15 56.5 0.0 5e-15 55.4 0.0 1.6 1 1 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 CBK23872.2 - 0.023 14.8 0.0 0.035 14.2 0.0 1.3 1 0 0 1 1 1 0 50S ribosome-binding GTPase G-alpha PF00503.20 CBK23872.2 - 0.027 13.6 0.0 5.4 6.1 0.0 2.1 1 1 0 2 2 2 0 G-protein alpha subunit GTP_EFTU PF00009.27 CBK23872.2 - 0.074 12.6 0.0 1.5 8.3 0.0 2.0 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_14 PF13173.6 CBK23872.2 - 0.12 12.4 0.0 0.17 12.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain PP-binding PF00550.25 CBK23873.2 - 1.9e-10 40.9 0.3 2.1e-10 40.8 0.3 1.0 1 0 0 1 1 1 1 Phosphopantetheine attachment site PP-binding_2 PF14573.6 CBK23873.2 - 0.0043 17.2 0.6 0.0052 17.0 0.6 1.2 1 0 0 1 1 1 1 Acyl-carrier Glu-tRNAGln PF02686.15 CBK23873.2 - 0.029 14.6 0.6 0.036 14.4 0.6 1.2 1 0 0 1 1 1 0 Glu-tRNAGln amidotransferase C subunit TAF PF02969.17 CBK23873.2 - 0.038 14.2 0.1 0.052 13.7 0.1 1.2 1 0 0 1 1 1 0 TATA box binding protein associated factor (TAF) DEAD PF00270.29 CBK23874.2 - 2.8e-42 144.4 0.0 4.9e-42 143.7 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CBK23874.2 - 1.4e-33 115.6 0.0 2.2e-32 111.7 0.0 2.6 3 0 0 3 3 3 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 CBK23874.2 - 0.074 13.3 0.1 0.19 12.0 0.1 1.8 1 1 0 1 1 1 0 AAA domain Peptidase_C1 PF00112.23 CBK23875.2 - 3.9e-73 246.1 3.1 5.1e-73 245.8 3.1 1.1 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 CBK23875.2 - 5.6e-11 42.7 2.7 1e-10 41.9 2.7 1.4 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.15 CBK23875.2 - 0.0055 15.5 2.0 0.71 8.6 0.1 2.4 2 1 0 2 2 2 2 Peptidase C1-like family Meiosis_expr PF15163.6 CBK23875.2 - 0.22 12.2 1.6 3.7 8.3 0.1 2.7 2 0 0 2 2 2 0 Meiosis-expressed ER PF01133.17 CBK23876.2 - 1.7e-16 60.0 0.1 2.1e-16 59.7 0.1 1.1 1 0 0 1 1 1 1 Enhancer of rudimentary HSP70 PF00012.20 CBK23877.2 - 1.1e-110 370.6 0.1 1e-88 298.1 0.1 2.0 2 0 0 2 2 2 2 Hsp70 protein MreB_Mbl PF06723.13 CBK23877.2 - 8e-11 41.3 0.4 4.4e-10 38.9 0.3 2.1 2 0 0 2 2 2 1 MreB/Mbl protein DUF4294 PF14127.6 CBK23877.2 - 0.079 12.9 0.0 0.18 11.7 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4294) CI-B14_5a PF07347.12 CBK23877.2 - 0.091 12.7 0.0 0.22 11.4 0.0 1.6 1 0 0 1 1 1 0 NADH:ubiquinone oxidoreductase subunit B14.5a (Complex I-B14.5a) DUF5525 PF17663.1 CBK23877.2 - 0.74 7.8 21.1 1.1 7.2 21.1 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5525) Lyase_1 PF00206.20 CBK23878.2 - 8.5e-88 294.7 0.0 1.2e-87 294.2 0.0 1.2 1 0 0 1 1 1 1 Lyase SWIB PF02201.18 CBK23878.2 - 1.4e-26 92.2 0.3 4.1e-16 58.6 0.0 2.7 2 0 0 2 2 2 2 SWIB/MDM2 domain FumaraseC_C PF10415.9 CBK23878.2 - 8.1e-17 61.4 0.1 2.8e-16 59.6 0.0 2.0 2 0 0 2 2 2 1 Fumarase C C-terminus DEK_C PF08766.11 CBK23878.2 - 6.7e-14 51.6 0.9 1.5e-13 50.4 0.9 1.7 1 0 0 1 1 1 1 DEK C terminal domain ANAPC4_WD40 PF12894.7 CBK23879.2 - 0.029 14.7 0.0 0.069 13.5 0.0 1.7 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 4 WD40 domain Tweety PF04906.13 CBK23879.2 - 0.1 11.3 0.1 0.13 10.9 0.1 1.1 1 0 0 1 1 1 0 Tweety CPSase_L_D2 PF02786.17 CBK23880.2 - 2e-72 243.1 0.0 3.3e-72 242.4 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 CBK23880.2 - 6.6e-44 149.0 0.0 1.6e-43 147.7 0.0 1.7 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 CBK23880.2 - 1.9e-36 124.4 0.0 4.2e-36 123.3 0.0 1.6 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.22 CBK23880.2 - 4.5e-18 64.9 0.2 9.6e-18 63.8 0.2 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme PCC_BT PF18140.1 CBK23880.2 - 1.6e-10 41.4 0.1 1.4e-05 25.4 0.0 2.5 1 1 1 2 2 2 2 Propionyl-coenzyme A carboxylase BT domain Biotin_lipoyl_2 PF13533.6 CBK23880.2 - 2.9e-08 33.4 0.1 1.6e-07 31.1 0.0 2.1 1 1 1 2 2 2 1 Biotin-lipoyl like Dala_Dala_lig_C PF07478.13 CBK23880.2 - 8e-08 32.1 0.1 3.5e-07 30.0 0.0 2.0 1 1 1 2 2 2 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 CBK23880.2 - 2.5e-05 23.9 0.0 5.3e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain DUF2118 PF09891.9 CBK23880.2 - 0.0022 18.0 0.0 0.0054 16.7 0.0 1.6 1 0 0 1 1 1 1 Uncharacterized protein conserved in archaea (DUF2118) GCV_H PF01597.19 CBK23880.2 - 0.003 17.5 0.1 0.011 15.6 0.1 2.0 1 0 0 1 1 1 1 Glycine cleavage H-protein PTS_EIIA_1 PF00358.20 CBK23880.2 - 0.0036 17.1 0.0 0.01 15.6 0.0 1.8 1 0 0 1 1 1 1 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 Peptidase_M23 PF01551.22 CBK23880.2 - 0.026 14.7 0.1 0.29 11.4 0.0 2.3 2 0 0 2 2 2 0 Peptidase family M23 RnfC_N PF13375.6 CBK23880.2 - 0.05 13.6 0.0 0.12 12.3 0.0 1.6 1 0 0 1 1 1 0 RnfC Barrel sandwich hybrid domain PYNP_C PF07831.13 CBK23880.2 - 0.064 12.9 0.0 0.2 11.3 0.0 1.8 1 0 0 1 1 1 0 Pyrimidine nucleoside phosphorylase C-terminal domain HlyD_D23 PF16576.5 CBK23880.2 - 0.092 11.9 0.0 0.19 10.9 0.0 1.5 1 0 0 1 1 1 0 Barrel-sandwich domain of CusB or HlyD membrane-fusion HlyD_3 PF13437.6 CBK23880.2 - 0.12 13.1 0.2 0.49 11.1 0.1 2.2 2 1 0 2 2 2 0 HlyD family secretion protein DNA_pol_E_B PF04042.16 CBK23881.2 - 7.6e-16 58.1 0.0 9.8e-16 57.7 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B COPIIcoated_ERV PF07970.12 CBK23882.2 - 1.6e-17 64.2 0.5 1.8e-17 63.9 0.5 1.0 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter Shisa PF13908.6 CBK23883.2 - 0.00069 19.9 3.0 0.00069 19.9 3.0 1.5 1 1 0 1 1 1 1 Wnt and FGF inhibitory regulator WBP-1 PF11669.8 CBK23883.2 - 0.0068 17.0 0.0 0.014 16.1 0.0 1.5 1 0 0 1 1 1 1 WW domain-binding protein 1 EphA2_TM PF14575.6 CBK23883.2 - 0.041 14.8 0.1 0.072 14.0 0.1 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain TMEM154 PF15102.6 CBK23883.2 - 0.066 13.1 1.3 0.12 12.3 1.0 1.4 1 1 0 1 1 1 0 TMEM154 protein family SUR7 PF06687.12 CBK23883.2 - 0.08 12.6 7.9 0.11 12.1 7.9 1.2 1 0 0 1 1 1 0 SUR7/PalI family GRP PF07172.11 CBK23883.2 - 1.3 9.8 13.0 3.5 8.4 10.0 2.2 2 0 0 2 2 2 0 Glycine rich protein family Sulfatase PF00884.23 CBK23884.2 - 0.14 11.5 0.0 0.22 10.9 0.0 1.3 1 0 0 1 1 1 0 Sulfatase TPT PF03151.16 CBK23886.2 - 3.1e-05 23.5 0.8 3.9e-05 23.1 0.8 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family AsmA_1 PF13109.6 CBK23886.2 - 0.079 12.4 0.1 0.11 11.9 0.1 1.2 1 0 0 1 1 1 0 AsmA-like C-terminal region Tenui_NS3 PF05310.12 CBK23886.2 - 0.18 11.9 0.0 0.25 11.4 0.0 1.1 1 0 0 1 1 1 0 Tenuivirus movement protein EamA PF00892.20 CBK23886.2 - 0.45 10.7 5.3 0.81 9.9 0.3 2.3 2 1 0 2 2 2 0 EamA-like transporter family Pkinase PF00069.25 CBK23887.2 - 1.2e-11 44.4 0.0 1.6e-11 44.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBK23887.2 - 5.3e-05 22.6 0.0 6.7e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 CBK23888.2 - 3.6e-31 108.5 0.0 1.6e-30 106.3 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBK23888.2 - 1.4e-18 67.1 0.0 3.7e-18 65.7 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CBK23888.2 - 2.2e-08 33.8 0.0 3e-08 33.3 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 CBK23888.2 - 0.00073 19.5 0.0 0.0011 19.0 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 CBK23888.2 - 0.18 11.2 0.0 0.27 10.6 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family WD40 PF00400.32 CBK23889.2 - 1.9e-19 69.6 10.6 6.4e-06 26.8 1.0 4.4 4 0 0 4 4 4 4 WD domain, G-beta repeat Ge1_WD40 PF16529.5 CBK23889.2 - 1.2e-06 27.7 1.5 0.0028 16.7 0.1 2.1 1 1 1 2 2 2 2 WD40 region of Ge1, enhancer of mRNA-decapping protein PALB2_WD40 PF16756.5 CBK23889.2 - 0.00032 19.7 2.3 0.0094 14.9 0.2 2.3 2 1 1 3 3 3 2 Partner and localizer of BRCA2 WD40 domain ANAPC4_WD40 PF12894.7 CBK23889.2 - 0.001 19.3 0.5 0.097 13.0 0.1 2.6 1 1 1 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 CBK23889.2 - 0.0024 17.2 0.1 0.0029 17.0 0.1 1.1 1 0 0 1 1 1 1 WD40-like domain DUF4784 PF16023.5 CBK23889.2 - 0.15 11.0 0.0 0.18 10.7 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4784) Pkinase PF00069.25 CBK23890.2 - 4e-15 55.9 0.0 9.5e-14 51.4 0.0 2.3 1 1 1 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBK23890.2 - 2.1e-13 50.1 0.0 1.7e-12 47.2 0.0 1.9 1 1 1 2 2 2 1 Protein tyrosine kinase DUF4111 PF13427.6 CBK23890.2 - 0.026 14.7 0.0 0.075 13.2 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4111) ERM PF00769.19 CBK23890.2 - 0.18 11.6 7.6 0.23 11.2 7.6 1.1 1 0 0 1 1 1 0 Ezrin/radixin/moesin family Histone PF00125.24 CBK23891.2 - 6.8e-53 178.5 3.8 7.5e-53 178.4 3.8 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 CBK23891.2 - 5.4e-05 23.5 0.1 7.8e-05 23.0 0.1 1.3 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 CBK23891.2 - 0.00048 20.2 0.2 0.00048 20.2 0.2 1.6 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold PAF PF15715.5 CBK23891.2 - 0.00081 20.0 1.1 0.00091 19.8 1.1 1.1 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CBFD_NFYB_HMF PF00808.23 CBK23891.2 - 0.0044 17.3 0.1 0.0088 16.3 0.1 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone EPL1 PF10513.9 CBK23893.2 - 3.2e-09 37.3 0.2 7.7e-09 36.1 0.2 1.6 1 0 0 1 1 1 1 Enhancer of polycomb-like KH_1 PF00013.29 CBK23894.2 - 0.001 18.8 2.0 0.0015 18.3 1.1 1.7 2 0 0 2 2 2 1 KH domain KH_8 PF17903.1 CBK23894.2 - 0.025 14.7 0.0 0.048 13.7 0.0 1.5 1 0 0 1 1 1 0 Krr1 KH1 domain tRNA-synt_2b PF00587.25 CBK23895.2 - 6.7e-39 133.7 0.1 1.1e-38 133.0 0.1 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.22 CBK23895.2 - 9.7e-24 83.7 4.7 1.9e-23 82.8 4.7 1.4 1 0 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain L_lactis_ph-MCP PF06673.11 CBK23895.2 - 0.31 10.0 4.7 0.51 9.3 4.7 1.3 1 0 0 1 1 1 0 Lactococcus lactis bacteriophage major capsid protein zf-RING_2 PF13639.6 CBK23896.2 - 7.1e-15 55.1 7.0 1.1e-14 54.5 7.0 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 CBK23896.2 - 7.5e-12 44.8 7.6 1.4e-11 43.9 7.6 1.5 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 CBK23896.2 - 1.7e-08 34.1 6.5 2.6e-08 33.5 6.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CBK23896.2 - 8.4e-08 32.0 5.6 1.3e-07 31.3 5.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CBK23896.2 - 9e-08 32.0 5.5 1.4e-07 31.4 5.5 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.7 CBK23896.2 - 3.8e-07 30.3 9.2 9.4e-07 29.0 9.2 1.6 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 CBK23896.2 - 4.6e-07 29.8 3.7 2.6e-06 27.3 4.1 1.9 1 1 1 2 2 2 1 RING-type zinc-finger zf-ANAPC11 PF12861.7 CBK23896.2 - 6e-06 26.2 5.6 1.1e-05 25.4 5.6 1.5 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.6 CBK23896.2 - 7.9e-06 25.6 7.3 1.3e-05 25.0 7.3 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 CBK23896.2 - 0.00017 21.4 8.0 0.0003 20.6 8.0 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 Zn_ribbon_17 PF17120.5 CBK23896.2 - 0.009 15.6 9.4 0.017 14.7 9.4 1.4 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-RING_4 PF14570.6 CBK23896.2 - 0.013 15.2 3.8 0.022 14.5 3.8 1.3 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain DUF1989 PF09347.10 CBK23896.2 - 0.025 14.2 0.1 0.036 13.7 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1989) FANCL_C PF11793.8 CBK23896.2 - 0.031 14.5 7.2 0.39 10.9 7.2 2.3 1 1 0 1 1 1 0 FANCL C-terminal domain zf-HC5HC2H_2 PF13832.6 CBK23896.2 - 0.054 13.7 3.6 0.086 13.0 3.6 1.4 1 0 0 1 1 1 0 PHD-zinc-finger like domain Baculo_RING PF05883.11 CBK23896.2 - 0.063 13.3 1.3 0.098 12.6 1.3 1.3 1 0 0 1 1 1 0 Baculovirus U-box/Ring-like domain RINGv PF12906.7 CBK23896.2 - 0.18 11.9 4.3 0.43 10.7 4.3 1.6 1 1 0 1 1 1 0 RING-variant domain zf-RING-like PF08746.11 CBK23896.2 - 0.22 11.9 5.2 0.41 11.0 5.2 1.5 1 1 0 1 1 1 0 RING-like domain Prok-RING_1 PF14446.6 CBK23896.2 - 0.24 11.4 9.5 0.39 10.7 6.3 2.2 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 Acetyltransf_1 PF00583.25 CBK23897.2 - 8e-07 29.3 0.0 1e-06 29.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 CBK23897.2 - 3.1e-05 23.9 0.0 4.4e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 CBK23897.2 - 0.0045 17.4 0.0 0.0069 16.8 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 CBK23897.2 - 0.028 14.4 0.0 0.051 13.6 0.0 1.5 1 0 0 1 1 1 0 FR47-like protein Acetyltransf_9 PF13527.7 CBK23897.2 - 0.1 12.6 0.0 0.16 12.0 0.0 1.5 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain TRAM1 PF08390.11 CBK23898.2 - 0.0028 17.2 0.8 0.0037 16.9 0.1 1.6 2 0 0 2 2 2 1 TRAM1-like protein FixQ PF05545.11 CBK23898.2 - 0.037 14.0 1.6 0.071 13.1 1.6 1.5 1 0 0 1 1 1 0 Cbb3-type cytochrome oxidase component FixQ eIF2A PF08662.11 CBK23900.2 - 1.3e-43 149.2 0.0 1.6e-43 148.8 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic translation initiation factor eIF2A WD40 PF00400.32 CBK23900.2 - 4.7e-05 24.1 0.2 1.2 10.1 0.0 3.2 2 1 0 2 2 2 2 WD domain, G-beta repeat DUF4226 PF10774.9 CBK23900.2 - 0.04 14.2 2.3 0.074 13.3 2.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4226) Metallophos PF00149.28 CBK23901.2 - 1.8e-34 120.0 0.1 2.4e-34 119.6 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 CBK23901.2 - 0.0017 18.7 0.5 0.0043 17.5 0.1 1.8 2 0 0 2 2 2 1 Serine-threonine protein phosphatase N-terminal domain DHHC PF01529.20 CBK23902.2 - 2.2e-19 69.9 9.7 2.7e-19 69.6 9.7 1.1 1 0 0 1 1 1 1 DHHC palmitoyltransferase zf-RanBP PF00641.18 CBK23902.2 - 0.026 13.8 1.3 0.069 12.5 1.3 1.7 1 0 0 1 1 1 0 Zn-finger in Ran binding protein and others MFS_1 PF07690.16 CBK23903.2 - 3e-06 26.4 0.0 3.3e-06 26.3 0.0 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily MMS19_C PF12460.8 CBK23904.2 - 0.074 12.1 0.0 0.15 11.1 0.0 1.5 1 0 0 1 1 1 0 RNAPII transcription regulator C-terminal HEAT PF02985.22 CBK23905.2 - 3.1e-09 36.3 3.0 2.8 8.4 0.0 6.6 6 0 0 6 6 6 3 HEAT repeat HEAT_EZ PF13513.6 CBK23905.2 - 7.6e-06 26.3 0.7 0.66 10.6 0.0 5.4 6 0 0 6 6 6 1 HEAT-like repeat Importin_rep_4 PF18808.1 CBK23905.2 - 1.1e-05 25.6 0.2 0.0001 22.5 0.0 2.8 3 0 0 3 3 3 1 Importin repeat HEAT_2 PF13646.6 CBK23905.2 - 0.00024 21.4 0.4 21 5.6 0.0 5.4 3 1 3 6 6 6 0 HEAT repeats Cnd1 PF12717.7 CBK23905.2 - 0.0092 16.0 4.6 15 5.6 0.2 4.4 3 2 2 5 5 5 2 non-SMC mitotic condensation complex subunit 1 MMS19_C PF12460.8 CBK23905.2 - 0.012 14.8 4.5 0.082 12.0 0.0 3.6 3 1 0 4 4 4 0 RNAPII transcription regulator C-terminal RTP1_C1 PF10363.9 CBK23905.2 - 0.013 15.7 0.7 0.13 12.4 0.2 2.9 3 1 0 3 3 3 0 Required for nuclear transport of RNA pol II C-terminus 1 RICTOR_V PF14668.6 CBK23905.2 - 0.046 14.0 0.9 1.3 9.3 0.1 3.5 4 0 0 4 4 4 0 Rapamycin-insensitive companion of mTOR, domain 5 DUF3385 PF11865.8 CBK23905.2 - 0.42 10.5 7.0 1.1 9.2 1.4 2.9 2 1 0 3 3 3 0 Domain of unknown function (DUF3385) DUF760 PF05542.11 CBK23905.2 - 0.89 10.0 4.2 11 6.4 1.1 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF760) DUF3199 PF11436.8 CBK23906.2 - 0.13 12.3 0.0 20 5.3 0.0 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF3199) LRR_8 PF13855.6 CBK23907.2 - 0.042 13.6 0.2 0.23 11.3 0.1 2.1 2 0 0 2 2 2 0 Leucine rich repeat hSac2 PF12456.8 CBK23907.2 - 0.049 13.3 0.3 9.1 6.0 0.0 3.2 1 1 2 3 3 3 0 Inositol phosphatase DNA_pol_phi PF04931.13 CBK23908.2 - 1.9e-28 99.1 34.1 2.6e-28 98.6 34.1 1.1 1 0 0 1 1 1 1 DNA polymerase phi Q_salvage PF10343.9 CBK23908.2 - 0.023 14.3 1.8 0.05 13.2 1.1 1.8 1 1 1 2 2 2 0 Potential Queuosine, Q, salvage protein family DUF913 PF06025.12 CBK23908.2 - 0.081 11.9 4.2 0.14 11.1 4.2 1.6 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) DUF3330 PF11809.8 CBK23908.2 - 0.092 12.8 0.9 2.3 8.3 0.0 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF3330) DUF4746 PF15928.5 CBK23908.2 - 0.12 11.7 17.0 0.29 10.5 17.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) DDHD PF02862.17 CBK23908.2 - 1.3 9.1 8.4 4.1 7.5 8.4 2.1 1 1 0 1 1 1 0 DDHD domain RR_TM4-6 PF06459.12 CBK23908.2 - 2 8.2 21.9 0.046 13.5 14.0 2.2 2 1 0 2 2 2 0 Ryanodine Receptor TM 4-6 Paf1 PF03985.13 CBK23908.2 - 2.5 7.0 30.6 5.8 5.8 30.6 1.6 1 0 0 1 1 1 0 Paf1 Zip PF02535.22 CBK23908.2 - 4.8 6.3 9.2 10 5.2 9.2 1.5 1 0 0 1 1 1 0 ZIP Zinc transporter SLC12 PF03522.15 CBK23908.2 - 5 6.0 9.9 18 4.2 8.8 2.0 2 0 0 2 2 2 0 Solute carrier family 12 CPSF100_C PF13299.6 CBK23908.2 - 5.3 7.2 16.7 0.33 11.1 10.5 2.1 2 1 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal CDC45 PF02724.14 CBK23908.2 - 8.8 4.5 25.9 20 3.3 25.9 1.5 1 0 0 1 1 1 0 CDC45-like protein DNA_pol_phi PF04931.13 CBK23909.2 - 6.1e-38 130.5 5.0 3.5e-37 128.0 3.2 2.4 2 1 0 2 2 2 1 DNA polymerase phi DUF4062 PF13271.6 CBK23910.2 - 0.094 13.1 0.1 0.13 12.7 0.1 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4062) Ribosomal_L28e PF01778.17 CBK23911.2 - 8.7e-38 129.6 2.9 8.7e-38 129.6 2.9 1.9 2 0 0 2 2 2 1 Ribosomal L28e protein family Mak16 PF04874.14 CBK23911.2 - 1.5e-21 76.9 18.8 1.5e-21 76.9 18.8 2.2 2 1 0 2 2 2 1 Mak16 protein C-terminal region Exonuc_VII_L PF02601.15 CBK23911.2 - 0.012 15.2 1.2 0.014 15.0 1.2 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit LMBR1 PF04791.16 CBK23911.2 - 1.5 7.6 3.2 1.8 7.4 3.2 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF2207 PF09972.9 CBK23911.2 - 3.1 6.4 7.3 2.8 6.6 6.1 1.4 1 1 1 2 2 2 0 Predicted membrane protein (DUF2207) DUF4168 PF13767.6 CBK23911.2 - 4.1 8.7 7.8 2.1 9.6 3.5 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4168) Sds3 PF08598.11 CBK23912.2 - 0.0028 17.7 5.2 0.0045 17.0 5.2 1.5 1 1 0 1 1 1 1 Sds3-like HSP20 PF00011.21 CBK23914.2 - 3.6e-19 68.8 0.0 5.2e-19 68.3 0.0 1.3 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 CBK23914.2 - 4.7e-05 22.9 0.1 0.00084 18.8 0.1 2.3 1 1 0 1 1 1 1 HSP20-like domain found in ArsA GvpH PF05455.11 CBK23914.2 - 0.00056 20.0 0.1 0.0016 18.5 0.0 1.7 1 1 1 2 2 2 1 GvpH NAD_binding_2 PF03446.15 CBK23915.2 - 7.6e-05 22.9 0.0 9.4e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Vert_HS_TF PF06546.11 CBK23915.2 - 0.14 11.8 0.1 0.16 11.6 0.1 1.2 1 0 0 1 1 1 0 Vertebrate heat shock transcription factor Bromodomain PF00439.25 CBK23916.2 - 2.3e-08 34.0 0.0 5.2e-08 32.8 0.0 1.7 1 0 0 1 1 1 1 Bromodomain BET PF17035.5 CBK23916.2 - 0.078 13.2 0.0 0.15 12.3 0.0 1.5 1 0 0 1 1 1 0 Bromodomain extra-terminal - transcription regulation DUF3619 PF12279.8 CBK23916.2 - 0.27 11.6 5.4 0.44 10.9 4.9 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3619) UPF0126 PF03458.13 CBK23917.2 - 0.00018 21.3 1.0 0.00018 21.3 1.0 2.3 3 0 0 3 3 3 1 UPF0126 domain DNA_pol3_delta2 PF13177.6 CBK23918.2 - 6.5e-12 45.5 0.3 1.1e-11 44.7 0.3 1.4 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA PF00004.29 CBK23918.2 - 6.8e-08 33.0 0.0 1.5e-07 31.9 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 CBK23918.2 - 0.00015 21.7 0.1 0.00026 21.0 0.1 1.3 1 0 0 1 1 1 1 Rad17 P-loop domain DUF815 PF05673.13 CBK23918.2 - 0.0069 15.6 0.0 0.012 14.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_16 PF13191.6 CBK23918.2 - 0.0085 16.5 0.0 0.079 13.3 0.0 2.4 1 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 CBK23918.2 - 0.01 16.1 0.1 0.054 13.8 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 CBK23918.2 - 0.048 13.8 0.0 0.15 12.2 0.0 1.9 1 1 0 1 1 1 0 AAA domain Bac_DnaA PF00308.18 CBK23918.2 - 0.074 12.9 0.0 2.4 7.9 0.0 2.5 2 0 0 2 2 2 0 Bacterial dnaA protein DNA_pol3_delta PF06144.13 CBK23918.2 - 0.075 12.8 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 DNA polymerase III, delta subunit Carboxyl_trans PF01039.22 CBK23919.2 - 2.4e-72 244.2 0.3 3.2e-72 243.8 0.3 1.1 1 0 0 1 1 1 1 Carboxyl transferase domain GTP_EFTU PF00009.27 CBK23920.2 - 7.8e-64 214.8 0.1 1.8e-63 213.6 0.1 1.6 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 CBK23920.2 - 4.9e-26 90.9 0.0 1.3e-25 89.5 0.0 1.8 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.24 CBK23920.2 - 3.5e-20 71.8 0.0 7.9e-20 70.7 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.6 CBK23920.2 - 1.3e-14 54.1 0.0 3.7e-14 52.6 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.25 CBK23920.2 - 7.6e-14 51.9 0.1 2e-13 50.5 0.1 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 CBK23920.2 - 0.00021 21.4 0.1 0.00096 19.2 0.1 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase zf-CCCH PF00642.24 CBK23921.2 - 3.6e-06 26.7 24.3 1.4e-05 24.9 5.1 3.0 2 1 1 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 CBK23921.2 - 0.00032 21.4 17.9 0.00049 20.8 3.0 3.0 2 1 2 4 4 4 2 Torus domain zf_CCCH_4 PF18345.1 CBK23921.2 - 0.0012 18.8 22.0 0.023 14.8 5.6 3.9 3 1 0 3 3 3 2 Zinc finger domain zf-CCCH_3 PF15663.5 CBK23921.2 - 0.0042 17.3 12.7 0.26 11.5 1.8 3.1 1 1 1 2 2 2 2 Zinc-finger containing family zf-CCCH_4 PF18044.1 CBK23921.2 - 0.0065 16.2 23.8 0.013 15.3 4.9 4.2 3 1 0 3 3 3 1 CCCH-type zinc finger zf-CCCH_2 PF14608.6 CBK23921.2 - 3.5 8.2 29.4 0.5 10.9 3.3 4.4 4 0 0 4 4 4 0 RNA-binding, Nab2-type zinc finger TBPIP PF07106.13 CBK23922.2 - 1.6e-22 79.2 1.0 2.9e-22 78.3 1.0 1.4 1 0 0 1 1 1 1 TBPIP/Hop2 winged helix domain DUF5082 PF16888.5 CBK23922.2 - 0.00025 21.3 4.7 0.024 14.9 0.4 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF5082) Penicillinase_R PF03965.16 CBK23922.2 - 0.0012 19.2 2.1 0.073 13.4 0.3 3.1 1 1 2 3 3 3 1 Penicillinase repressor DivIC PF04977.15 CBK23922.2 - 0.0013 18.4 7.4 0.11 12.3 1.9 3.0 1 1 1 2 2 2 2 Septum formation initiator KASH_CCD PF14662.6 CBK23922.2 - 0.0024 17.7 7.4 0.0024 17.7 7.4 1.9 2 0 0 2 2 2 1 Coiled-coil region of CCDC155 or KASH Spc7 PF08317.11 CBK23922.2 - 0.0026 16.7 11.2 0.14 11.0 0.8 2.0 1 1 1 2 2 2 2 Spc7 kinetochore protein ATG16 PF08614.11 CBK23922.2 - 0.0046 17.2 9.5 0.074 13.3 9.6 2.1 1 1 0 1 1 1 1 Autophagy protein 16 (ATG16) DUF1192 PF06698.11 CBK23922.2 - 0.0059 16.6 12.2 0.019 15.0 1.3 3.4 2 1 1 3 3 3 1 Protein of unknown function (DUF1192) Snapin_Pallidin PF14712.6 CBK23922.2 - 0.018 15.5 2.8 0.046 14.1 2.8 1.7 1 0 0 1 1 1 0 Snapin/Pallidin ADIP PF11559.8 CBK23922.2 - 0.023 14.8 8.3 0.79 9.8 3.8 2.7 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding LZ3wCH PF18517.1 CBK23922.2 - 0.025 14.6 0.2 0.13 12.4 0.0 2.5 2 0 0 2 2 1 0 Leucine zipper with capping helix domain APG6_N PF17675.1 CBK23922.2 - 0.029 14.9 15.0 0.1 13.1 13.7 2.3 1 1 1 2 2 2 0 Apg6 coiled-coil region WXG100 PF06013.12 CBK23922.2 - 0.046 14.0 3.4 0.67 10.2 1.7 2.9 2 1 0 2 2 2 0 Proteins of 100 residues with WXG DUF3811 PF11656.8 CBK23922.2 - 0.048 14.0 2.5 0.099 13.0 0.0 2.2 2 1 0 2 2 2 0 YjbD family (DUF3811) Baculo_PEP_C PF04513.12 CBK23922.2 - 0.07 13.2 0.4 0.22 11.5 0.4 1.7 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus SlyX PF04102.12 CBK23922.2 - 0.072 13.7 6.8 4 8.1 1.8 3.1 1 1 2 3 3 3 0 SlyX Golgin_A5 PF09787.9 CBK23922.2 - 0.079 12.4 9.8 0.1 12.0 9.8 1.3 1 0 0 1 1 1 0 Golgin subfamily A member 5 HALZ PF02183.18 CBK23922.2 - 0.1 12.8 2.5 0.53 10.5 1.5 2.6 2 0 0 2 2 2 0 Homeobox associated leucine zipper ZapB PF06005.12 CBK23922.2 - 0.12 12.9 9.4 38 4.8 9.4 2.6 1 1 0 1 1 1 0 Cell division protein ZapB BLOC1_2 PF10046.9 CBK23922.2 - 0.12 12.7 6.4 0.06 13.7 3.7 1.9 2 0 0 2 2 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Rx_N PF18052.1 CBK23922.2 - 0.13 12.5 3.1 0.34 11.2 3.1 1.8 1 0 0 1 1 1 0 Rx N-terminal domain DUF5320 PF17253.2 CBK23922.2 - 0.13 13.3 2.5 0.16 13.1 1.3 1.8 1 1 1 2 2 1 0 Family of unknown function (DUF5320) FlxA PF14282.6 CBK23922.2 - 0.16 12.0 5.4 0.18 11.8 3.8 1.9 1 1 1 2 2 2 0 FlxA-like protein DASH_Spc19 PF08287.11 CBK23922.2 - 0.2 11.5 5.8 0.38 10.6 5.7 1.5 1 1 0 1 1 1 0 Spc19 DUF1664 PF07889.12 CBK23922.2 - 0.2 11.7 3.6 0.43 10.6 2.7 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) ABC_tran_CTD PF16326.5 CBK23922.2 - 0.21 11.9 18.0 7.1 7.0 6.6 3.1 1 1 1 2 2 2 0 ABC transporter C-terminal domain Cnn_1N PF07989.11 CBK23922.2 - 0.25 11.5 8.2 0.32 11.2 3.7 2.9 1 1 2 3 3 3 0 Centrosomin N-terminal motif 1 bZIP_1 PF00170.21 CBK23922.2 - 0.26 11.4 9.5 0.62 10.2 4.8 3.0 1 1 0 2 2 2 0 bZIP transcription factor FUSC PF04632.12 CBK23922.2 - 0.28 9.7 2.4 0.34 9.4 2.4 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family TMF_DNA_bd PF12329.8 CBK23922.2 - 0.28 11.2 11.7 3 7.9 11.5 2.6 1 1 0 1 1 1 0 TATA element modulatory factor 1 DNA binding Prominin PF05478.11 CBK23922.2 - 0.34 8.8 4.3 0.43 8.5 3.9 1.3 1 1 0 1 1 1 0 Prominin Cep57_CLD_2 PF14197.6 CBK23922.2 - 0.36 10.9 6.1 0.2 11.8 2.2 2.3 1 1 1 2 2 2 0 Centrosome localisation domain of PPC89 TMPIT PF07851.13 CBK23922.2 - 0.4 9.9 4.7 0.67 9.1 4.3 1.6 1 1 1 2 2 2 0 TMPIT-like protein GAS PF13851.6 CBK23922.2 - 0.41 10.0 11.1 1.3 8.3 11.1 2.0 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding DUF465 PF04325.13 CBK23922.2 - 0.41 10.7 4.9 2.7 8.1 1.9 3.0 1 1 1 2 2 2 0 Protein of unknown function (DUF465) E2F_CC-MB PF16421.5 CBK23922.2 - 0.43 11.0 4.0 6.9 7.1 1.8 2.6 1 1 1 2 2 2 0 E2F transcription factor CC-MB domain Ax_dynein_light PF10211.9 CBK23922.2 - 0.43 10.5 9.6 0.53 10.2 7.0 2.3 1 1 1 2 2 2 0 Axonemal dynein light chain DUF1910 PF08928.10 CBK23922.2 - 0.45 10.5 4.1 14 5.7 0.0 2.7 2 1 1 3 3 2 0 Domain of unknown function (DUF1910) Mnd1 PF03962.15 CBK23922.2 - 0.56 10.5 4.5 1.1 9.6 0.1 2.8 2 1 1 3 3 3 0 Mnd1 HTH domain Prefoldin_2 PF01920.20 CBK23922.2 - 0.64 10.0 9.9 5.9 6.9 4.5 3.0 1 1 1 2 2 2 0 Prefoldin subunit TPR_MLP1_2 PF07926.12 CBK23922.2 - 0.64 10.1 11.7 4.1 7.5 11.7 2.3 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein DUF724 PF05266.14 CBK23922.2 - 0.72 9.6 9.8 0.41 10.4 1.9 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF724) YabA PF06156.13 CBK23922.2 - 0.81 10.4 9.3 4.3 8.0 1.8 2.7 2 1 1 3 3 2 0 Initiation control protein YabA FapA PF03961.13 CBK23922.2 - 0.91 8.1 10.1 0.42 9.2 5.7 2.0 1 1 1 2 2 2 0 Flagellar Assembly Protein A Fez1 PF06818.15 CBK23922.2 - 0.99 9.8 10.5 1.6 9.2 10.4 1.5 1 1 0 1 1 1 0 Fez1 PRKG1_interact PF15898.5 CBK23922.2 - 1.6 9.7 11.8 0.74 10.7 2.3 3.2 1 1 1 2 2 2 0 cGMP-dependent protein kinase interacting domain Fib_alpha PF08702.10 CBK23922.2 - 1.8 8.8 6.2 6.4 7.0 4.5 2.2 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Seryl_tRNA_N PF02403.22 CBK23922.2 - 1.9 8.7 9.8 2.1 8.6 7.6 2.2 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Swi5 PF07061.11 CBK23922.2 - 2.1 8.5 6.9 24 5.1 6.9 2.9 1 1 0 1 1 1 0 Swi5 FAM76 PF16046.5 CBK23922.2 - 2.3 7.5 6.3 11 5.3 6.3 1.9 1 1 0 1 1 1 0 FAM76 protein DUF1319 PF07028.11 CBK23922.2 - 2.7 8.3 6.8 1.9 8.7 1.9 2.7 1 1 1 3 3 3 0 Protein of unknown function (DUF1319) V-SNARE PF05008.15 CBK23922.2 - 3.1 8.3 11.0 8.7 6.8 2.1 3.1 1 1 2 3 3 3 0 Vesicle transport v-SNARE protein N-terminus CCDC-167 PF15188.6 CBK23922.2 - 5.3 7.5 10.1 11 6.4 5.2 3.0 1 1 2 3 3 3 0 Coiled-coil domain-containing protein 167 FlaC_arch PF05377.11 CBK23922.2 - 5.7 7.4 13.9 0.79 10.2 3.1 3.5 2 1 2 4 4 3 0 Flagella accessory protein C (FlaC) Spc24 PF08286.11 CBK23922.2 - 5.9 7.2 13.5 1.1 9.5 5.1 2.8 2 1 1 3 3 2 0 Spc24 subunit of Ndc80 Ribosomal_L29 PF00831.23 CBK23922.2 - 6.3 6.9 8.9 0.6 10.1 0.9 2.7 1 1 1 2 2 2 0 Ribosomal L29 protein Pkinase PF00069.25 CBK23923.2 - 3.5e-25 88.9 0.0 4.1e-25 88.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBK23923.2 - 4.6e-12 45.8 0.0 5.7e-12 45.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CBK23923.2 - 9.7e-05 21.3 0.0 0.00013 20.9 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 CBK23923.2 - 0.019 14.9 0.0 0.17 11.8 0.0 2.3 2 1 1 3 3 3 0 Phosphotransferase enzyme family zf-UBP_var PF17807.1 CBK23924.2 - 7e-22 77.0 1.1 1.2e-21 76.2 1.1 1.4 1 0 0 1 1 1 1 Variant UBP zinc finger UBA_4 PF14555.6 CBK23924.2 - 1.3e-07 31.3 0.0 2.5e-07 30.4 0.0 1.5 1 0 0 1 1 1 1 UBA-like domain zf-UBP PF02148.19 CBK23924.2 - 0.0021 18.3 2.4 0.0021 18.3 2.4 2.2 2 1 0 2 2 2 1 Zn-finger in ubiquitin-hydrolases and other protein DUF2180 PF09947.9 CBK23924.2 - 0.012 15.5 1.0 0.042 13.8 0.2 2.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2180) zf-RING_10 PF16685.5 CBK23924.2 - 4.1 7.6 8.2 0.16 12.1 1.2 2.3 3 0 0 3 3 3 0 zinc RING finger of MSL2 UCH PF00443.29 CBK23925.2 - 1.9e-24 86.6 0.1 2.5e-24 86.1 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 CBK23925.2 - 6.2e-17 61.7 10.9 6.2e-17 61.7 10.9 2.7 4 0 0 4 4 4 1 Zn-finger in ubiquitin-hydrolases and other protein UCH_1 PF13423.6 CBK23925.2 - 1.1e-11 45.0 3.5 3.2e-09 36.8 3.5 2.1 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Peptidase_C98 PF15499.6 CBK23925.2 - 7.1e-06 25.7 2.1 0.00072 19.1 0.2 2.3 2 0 0 2 2 2 2 Ubiquitin-specific peptidase-like, SUMO isopeptidase UCH PF00443.29 CBK23926.2 - 1.2e-09 38.1 0.1 1.2e-09 38.1 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 CBK23926.2 - 0.00052 19.7 0.1 0.00062 19.4 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Ribosomal_S8e PF01201.22 CBK23927.2 - 3.1e-46 157.0 4.7 1.5e-45 154.8 4.7 1.9 1 1 0 1 1 1 1 Ribosomal protein S8e SesA PF17107.5 CBK23928.2 - 0.1 12.8 0.0 0.14 12.3 0.0 1.2 1 0 0 1 1 1 0 N-terminal domain on NACHT_NTPase and P-loop NTPases Trypsin_2 PF13365.6 CBK23929.2 - 0.0082 17.1 0.1 0.019 15.9 0.1 1.8 1 1 0 1 1 1 1 Trypsin-like peptidase domain SAP PF02037.27 CBK23930.2 - 4.6e-07 29.4 0.0 7.3e-07 28.8 0.0 1.3 1 0 0 1 1 1 1 SAP domain Tho1_MOS11_C PF18592.1 CBK23930.2 - 0.014 15.1 0.2 0.03 14.1 0.2 1.5 1 0 0 1 1 1 0 Tho1/MOS11 C-terminal domain fn3 PF00041.21 CBK23931.2 - 5e-10 39.6 0.1 0.00039 20.7 0.0 4.8 5 0 0 5 5 5 3 Fibronectin type III domain Big_5 PF13205.6 CBK23931.2 - 1.1e-05 26.1 3.0 0.15 12.7 0.1 4.7 4 1 1 5 5 5 2 Bacterial Ig-like domain Pur_ac_phosph_N PF16656.5 CBK23931.2 - 1.2e-05 25.8 0.0 0.22 12.1 0.0 4.6 2 2 0 2 2 2 2 Purple acid Phosphatase, N-terminal domain Pentapeptide_2 PF01469.18 CBK23931.2 - 0.086 12.7 0.0 0.17 11.8 0.0 1.4 1 0 0 1 1 1 0 Pentapeptide repeats (8 copies) Myco_19_kDa PF05481.12 CBK23931.2 - 0.13 12.5 0.2 0.74 10.1 0.0 2.3 3 0 0 3 3 3 0 Mycobacterium 19 kDa lipoprotein antigen Mnd1 PF03962.15 CBK23932.2 - 6.9e-16 58.3 1.0 1.5e-15 57.2 1.0 1.6 1 0 0 1 1 1 1 Mnd1 HTH domain LZ3wCH PF18517.1 CBK23932.2 - 1.4e-15 57.1 0.2 1.4e-15 57.1 0.2 2.6 4 0 0 4 4 3 1 Leucine zipper with capping helix domain Atg14 PF10186.9 CBK23932.2 - 0.001 18.2 7.5 0.0013 17.9 7.5 1.1 1 0 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 YscO PF07321.12 CBK23932.2 - 0.0033 17.4 5.9 0.0054 16.7 5.9 1.4 1 0 0 1 1 1 1 Type III secretion protein YscO AIP3 PF03915.13 CBK23932.2 - 0.0094 15.1 5.9 0.011 14.9 5.6 1.3 1 1 0 1 1 1 1 Actin interacting protein 3 DivIC PF04977.15 CBK23932.2 - 0.011 15.5 9.5 0.48 10.2 1.0 2.8 2 1 1 3 3 3 0 Septum formation initiator Spc7 PF08317.11 CBK23932.2 - 0.013 14.4 7.4 0.02 13.8 7.4 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein Jnk-SapK_ap_N PF09744.9 CBK23932.2 - 0.016 15.4 7.1 0.027 14.7 7.1 1.3 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 Snapin_Pallidin PF14712.6 CBK23932.2 - 0.019 15.4 2.3 2.4 8.7 0.4 2.5 2 0 0 2 2 2 0 Snapin/Pallidin ParBc PF02195.18 CBK23932.2 - 0.024 14.9 0.3 0.084 13.2 0.1 1.9 1 1 1 2 2 2 0 ParB-like nuclease domain ABC_tran_CTD PF16326.5 CBK23932.2 - 0.068 13.4 6.4 0.17 12.2 6.4 1.8 1 0 0 1 1 1 0 ABC transporter C-terminal domain Pil1 PF13805.6 CBK23932.2 - 0.092 12.2 8.1 0.12 11.9 6.2 1.8 1 1 1 2 2 2 0 Eisosome component PIL1 DUF1640 PF07798.11 CBK23932.2 - 0.14 12.2 4.8 0.19 11.8 4.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) DUF2252 PF10009.9 CBK23932.2 - 0.15 11.1 1.9 0.2 10.7 1.9 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2252) Seryl_tRNA_N PF02403.22 CBK23932.2 - 0.19 12.0 7.7 0.31 11.3 6.1 2.0 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain ZapB PF06005.12 CBK23932.2 - 0.39 11.2 10.9 1.1 9.7 9.4 2.2 1 1 0 2 2 2 0 Cell division protein ZapB TMPIT PF07851.13 CBK23932.2 - 0.68 9.1 3.7 0.9 8.7 3.7 1.2 1 0 0 1 1 1 0 TMPIT-like protein FapA PF03961.13 CBK23932.2 - 0.75 8.3 11.3 0.13 10.8 5.8 2.0 1 1 0 2 2 2 0 Flagellar Assembly Protein A MctB PF11382.8 CBK23932.2 - 0.83 9.3 5.0 2.2 7.9 0.2 2.1 1 1 1 2 2 2 0 Copper transport outer membrane protein, MctB OmpH PF03938.14 CBK23932.2 - 0.87 9.9 7.4 0.22 11.9 3.4 1.8 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) Prefoldin PF02996.17 CBK23932.2 - 0.91 9.4 6.0 5.8 6.9 1.1 2.6 1 1 1 2 2 2 0 Prefoldin subunit FlaC_arch PF05377.11 CBK23932.2 - 3.8 8.0 9.6 2.8 8.4 0.3 3.5 3 1 0 4 4 4 0 Flagella accessory protein C (FlaC) HALZ PF02183.18 CBK23932.2 - 3.8 7.8 10.6 1.3 9.3 0.8 2.7 3 0 0 3 3 3 0 Homeobox associated leucine zipper DUF4140 PF13600.6 CBK23932.2 - 4.8 7.7 9.1 8.1 7.0 0.6 2.7 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) Aa_trans PF01490.18 CBK23933.2 - 7.1e-43 146.8 32.2 9.9e-43 146.4 32.2 1.3 1 1 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 CBK23933.2 - 0.00014 21.0 28.3 0.0007 18.7 27.6 2.3 1 1 0 1 1 1 1 Tryptophan/tyrosine permease family Choline_kinase PF01633.20 CBK23936.2 - 1.2e-05 25.0 1.0 3.4e-05 23.6 0.0 2.1 1 1 0 2 2 2 1 Choline/ethanolamine kinase Choline_kinase PF01633.20 CBK23937.2 - 3.6e-17 62.7 0.0 4.5e-17 62.3 0.0 1.0 1 0 0 1 1 1 1 Choline/ethanolamine kinase Pro_isomerase PF00160.21 CBK23938.2 - 1.6e-45 155.2 0.0 1.9e-45 155.0 0.0 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Synaptobrevin PF00957.21 CBK23939.2 - 5.9e-27 93.3 2.5 9.7e-27 92.6 2.5 1.4 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.6 CBK23939.2 - 4.2e-14 52.3 0.5 8.2e-14 51.4 0.5 1.5 1 0 0 1 1 1 1 Regulated-SNARE-like domain NAD_synthase PF02540.17 CBK23940.2 - 5.3e-31 107.6 0.0 8.2e-31 107.0 0.0 1.3 1 1 0 1 1 1 1 NAD synthase tRNA_Me_trans PF03054.16 CBK23940.2 - 0.13 11.0 0.1 0.18 10.6 0.1 1.2 1 0 0 1 1 1 0 tRNA methyl transferase PAPS_reduct PF01507.19 CBK23940.2 - 0.14 12.2 0.0 0.22 11.6 0.0 1.3 1 0 0 1 1 1 0 Phosphoadenosine phosphosulfate reductase family ATP_bind_3 PF01171.20 CBK23940.2 - 0.19 11.5 0.7 0.68 9.7 0.0 1.9 2 0 0 2 2 2 0 PP-loop family Ctf8 PF09696.10 CBK23941.2 - 5.2e-08 33.3 0.4 2.1e-06 28.2 0.1 2.7 1 1 1 2 2 2 1 Ctf8 Adaptin_N PF01602.20 CBK23942.2 - 8e-93 311.8 1.0 9.4e-93 311.5 1.0 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 CBK23942.2 - 1.5e-07 31.6 1.6 0.027 14.5 0.5 3.6 2 1 1 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 CBK23942.2 - 2e-05 24.9 0.1 3.1 8.2 0.0 4.1 3 1 0 3 3 3 2 HEAT repeats HEAT PF02985.22 CBK23942.2 - 0.0018 18.3 1.0 3.6 8.1 0.2 4.4 4 0 0 4 4 4 1 HEAT repeat Herpes_glycop PF01528.16 CBK23942.2 - 0.023 13.6 0.0 0.039 12.8 0.0 1.2 1 0 0 1 1 1 0 Herpesvirus glycoprotein M Cnd3 PF12719.7 CBK23942.2 - 1.2 8.3 9.0 0.12 11.5 0.2 3.3 4 1 1 5 5 5 0 Nuclear condensing complex subunits, C-term domain Epimerase PF01370.21 CBK23943.2 - 4.3e-05 23.1 0.0 0.00024 20.6 0.0 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 CBK23943.2 - 0.00013 21.1 0.0 0.0089 15.2 0.0 2.6 1 1 0 1 1 1 1 RmlD substrate binding domain NmrA PF05368.13 CBK23943.2 - 0.0074 15.9 0.0 0.34 10.4 0.0 2.1 2 0 0 2 2 2 1 NmrA-like family 3Beta_HSD PF01073.19 CBK23943.2 - 0.02 13.9 0.0 0.075 12.0 0.0 1.8 1 1 1 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 CBK23943.2 - 0.032 14.1 0.0 0.051 13.5 0.0 1.3 1 0 0 1 1 1 0 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 CBK23943.2 - 0.062 13.6 0.0 0.15 12.3 0.0 1.6 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain ACBP PF00887.19 CBK23946.2 - 8.6e-29 99.6 0.4 1e-28 99.4 0.4 1.0 1 0 0 1 1 1 1 Acyl CoA binding protein FERM_M PF00373.18 CBK23946.2 - 0.14 12.6 0.1 0.25 11.8 0.1 1.3 1 1 0 1 1 1 0 FERM central domain DUF4090 PF13319.6 CBK23947.2 - 0.053 13.8 1.0 0.067 13.5 1.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4090) IATP PF04568.12 CBK23947.2 - 0.13 12.7 5.3 0.22 12.0 5.3 1.4 1 1 0 1 1 1 0 Mitochondrial ATPase inhibitor, IATP Acyl_transf_1 PF00698.21 CBK23948.2 - 2.6e-08 33.7 0.0 3.2e-08 33.5 0.0 1.1 1 0 0 1 1 1 1 Acyl transferase domain RabGAP-TBC PF00566.18 CBK23949.2 - 1.8e-12 47.4 3.0 1.8e-12 47.4 3.0 1.9 2 0 0 2 2 2 1 Rab-GTPase-TBC domain DivIVA PF05103.13 CBK23949.2 - 0.0077 16.3 1.4 0.82 9.8 0.0 3.1 3 0 0 3 3 3 1 DivIVA protein Uds1 PF15456.6 CBK23949.2 - 0.19 11.9 2.5 2.5 8.3 2.5 2.3 1 1 0 1 1 1 0 Up-regulated During Septation PhoLip_ATPase_C PF16212.5 CBK23950.2 - 7.3e-56 189.7 29.1 7.3e-56 189.7 29.1 2.3 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 CBK23950.2 - 4.2e-11 42.4 2.0 1.9e-10 40.3 2.0 2.1 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 CBK23950.2 - 1.6e-07 31.8 0.2 0.0039 17.5 0.1 3.4 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 CBK23950.2 - 3e-07 30.4 0.0 8.9e-07 28.9 0.0 1.8 1 0 0 1 1 1 1 Cation transport ATPase (P-type) E1-E2_ATPase PF00122.20 CBK23950.2 - 0.0024 17.4 0.0 0.0024 17.4 0.0 3.0 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase_3 PF08282.12 CBK23950.2 - 0.055 13.2 0.0 0.055 13.2 0.0 3.2 3 0 0 3 3 3 0 haloacid dehalogenase-like hydrolase E2F_TDP PF02319.20 CBK23951.2 - 1.1e-12 47.8 0.0 1.3e-12 47.5 0.0 1.1 1 0 0 1 1 1 1 E2F/DP family winged-helix DNA-binding domain HTH_38 PF13936.6 CBK23951.2 - 0.04 13.7 0.0 0.067 13.0 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain Lsm_interact PF05391.11 CBK23951.2 - 3.9 7.1 6.2 4.1 7.0 1.0 2.4 2 0 0 2 2 2 0 Lsm interaction motif LRR_8 PF13855.6 CBK23952.2 - 0.0036 17.0 0.2 0.045 13.5 0.1 2.7 2 1 0 2 2 2 1 Leucine rich repeat LRR_4 PF12799.7 CBK23952.2 - 0.017 15.5 0.7 0.92 10.0 0.0 3.5 2 2 1 3 3 3 0 Leucine Rich repeats (2 copies) GDI PF00996.18 CBK23953.2 - 3.7e-181 602.4 0.0 4.4e-181 602.1 0.0 1.0 1 0 0 1 1 1 1 GDP dissociation inhibitor NAD_binding_8 PF13450.6 CBK23953.2 - 0.00038 20.6 0.0 0.00083 19.5 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain SNF2_N PF00176.23 CBK23954.2 - 2.1e-56 191.1 0.1 1.3e-55 188.6 0.1 1.9 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 CBK23954.2 - 1.5e-19 70.4 0.0 2.1e-18 66.7 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain IFN-gamma PF00714.17 CBK23954.2 - 0.15 11.9 0.4 1.4 8.8 0.2 2.3 2 0 0 2 2 2 0 Interferon gamma Aldedh PF00171.22 CBK23955.2 - 1.3e-168 561.3 0.0 1.5e-168 561.1 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 CBK23955.2 - 0.2 11.0 0.0 2.3 7.6 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1487) NIF PF03031.18 CBK23956.2 - 5.6e-51 172.4 0.0 9.8e-51 171.6 0.0 1.4 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase HAD PF12710.7 CBK23956.2 - 0.0066 16.9 0.1 0.046 14.1 0.0 2.0 1 1 1 2 2 2 1 haloacid dehalogenase-like hydrolase HMG_box PF00505.19 CBK23957.2 - 5.6e-24 84.3 1.7 9.2e-24 83.7 1.7 1.4 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 CBK23957.2 - 1e-14 54.8 0.9 1.6e-14 54.2 0.9 1.3 1 0 0 1 1 1 1 HMG-box domain HMG_box_5 PF14887.6 CBK23957.2 - 0.14 12.2 2.0 0.12 12.4 0.6 1.6 2 0 0 2 2 2 0 HMG (high mobility group) box 5 DUF1295 PF06966.12 CBK23959.2 - 1.2e-22 80.6 0.1 1.8e-22 80.1 0.1 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF1295) Steroid_dh PF02544.16 CBK23959.2 - 0.00014 21.9 0.3 0.00014 21.9 0.3 2.8 1 1 1 2 2 2 1 3-oxo-5-alpha-steroid 4-dehydrogenase PEMT PF04191.13 CBK23959.2 - 0.25 11.8 5.7 0.15 12.4 0.6 3.1 2 2 0 2 2 2 0 Phospholipid methyltransferase ICMT PF04140.14 CBK23959.2 - 1.1 9.7 0.0 1.1 9.7 0.0 3.0 3 1 0 3 3 3 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family zf_CCCH_4 PF18345.1 CBK23960.2 - 8.6e-12 44.7 15.6 2.5e-08 33.7 5.7 3.5 2 1 0 2 2 2 2 Zinc finger domain zf-CCCH_4 PF18044.1 CBK23960.2 - 2.8e-10 39.8 18.3 2.6e-07 30.3 1.3 3.1 3 0 0 3 3 3 2 CCCH-type zinc finger zf-CCCH PF00642.24 CBK23960.2 - 3.6e-08 33.1 8.8 1.9e-05 24.4 0.4 2.8 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-RING_2 PF13639.6 CBK23960.2 - 4.7e-08 33.2 10.3 4.7e-08 33.2 10.3 2.5 3 0 0 3 3 3 1 Ring finger domain Torus PF16131.5 CBK23960.2 - 8e-07 29.7 4.2 0.019 15.6 0.8 2.2 2 0 0 2 2 2 2 Torus domain zf-CCCH_2 PF14608.6 CBK23960.2 - 4.7e-06 26.9 13.2 0.012 16.1 2.0 2.8 2 0 0 2 2 2 2 RNA-binding, Nab2-type zinc finger zf-C3HC4 PF00097.25 CBK23960.2 - 1.4e-05 24.9 8.6 3.1e-05 23.7 8.6 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CBK23960.2 - 5.1e-05 23.2 6.5 0.00014 21.8 6.5 1.8 1 0 0 1 1 1 1 RING-type zinc-finger Prok-RING_4 PF14447.6 CBK23960.2 - 0.00015 21.5 9.4 0.0025 17.6 9.9 2.5 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 CBK23960.2 - 0.00047 20.1 10.7 0.0014 18.6 9.9 2.2 1 1 1 2 2 2 1 zinc-RING finger domain zf-rbx1 PF12678.7 CBK23960.2 - 0.0011 19.3 9.9 0.0052 17.0 9.8 2.2 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_11 PF17123.5 CBK23960.2 - 0.0027 17.4 7.5 0.0064 16.2 7.5 1.7 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_4 PF15227.6 CBK23960.2 - 0.0037 17.4 2.5 0.0037 17.4 2.5 2.4 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING Baculo_RING PF05883.11 CBK23960.2 - 0.039 13.9 2.4 0.11 12.5 2.4 1.8 1 1 0 1 1 1 0 Baculovirus U-box/Ring-like domain zf-RING_4 PF14570.6 CBK23960.2 - 0.11 12.3 6.4 0.46 10.3 6.4 2.1 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-C3HC4_2 PF13923.6 CBK23960.2 - 0.34 10.8 17.8 0.2 11.6 13.9 2.6 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 CBK23960.2 - 0.38 10.8 7.8 0.12 12.4 4.3 2.0 1 1 1 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger He_PIG PF05345.12 CBK23961.2 - 3.1e-06 27.3 5.8 1.2e-05 25.3 5.8 2.1 1 0 0 1 1 1 1 Putative Ig domain TMEM154 PF15102.6 CBK23961.2 - 0.0081 16.1 2.7 0.015 15.2 2.7 1.3 1 0 0 1 1 1 1 TMEM154 protein family EphA2_TM PF14575.6 CBK23961.2 - 0.013 16.4 1.3 0.025 15.5 1.3 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Orf78 PF06024.12 CBK23961.2 - 0.013 15.8 1.1 0.027 14.8 1.1 1.4 1 0 0 1 1 1 0 Orf78 (ac78) Baculo_11_kDa PF06143.11 CBK23961.2 - 0.013 15.0 3.2 0.027 14.0 3.2 1.4 1 0 0 1 1 1 0 Baculovirus 11 kDa family OAD_gamma PF04277.13 CBK23961.2 - 0.016 15.7 5.7 0.035 14.7 5.7 1.5 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain DUF5305 PF17231.2 CBK23961.2 - 0.064 12.6 2.8 0.11 11.9 2.8 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5305) OSTbeta PF15048.6 CBK23961.2 - 0.065 13.4 0.5 0.12 12.5 0.5 1.4 1 0 0 1 1 1 0 Organic solute transporter subunit beta protein DUF4834 PF16118.5 CBK23961.2 - 0.1 13.6 0.1 0.22 12.5 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) tRNA_anti-like PF12869.7 CBK23961.2 - 0.19 11.3 3.2 0.37 10.4 3.2 1.4 1 0 0 1 1 1 0 tRNA_anti-like DUF5385 PF17359.2 CBK23961.2 - 0.2 11.2 3.7 0.32 10.5 3.7 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5385) F5_F8_type_C PF00754.25 CBK23961.2 - 0.22 11.7 0.1 0.22 11.7 0.1 2.7 3 0 0 3 3 3 0 F5/8 type C domain Shisa PF13908.6 CBK23961.2 - 0.68 10.1 8.2 0.033 14.4 2.0 1.9 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator SP_C-Propep PF08999.10 CBK23961.2 - 0.78 9.6 5.1 1.9 8.3 5.1 1.6 1 0 0 1 1 1 0 Surfactant protein C, N terminal propeptide RIFIN PF02009.16 CBK23961.2 - 0.85 9.5 6.7 0.23 11.3 3.4 1.6 2 0 0 2 2 2 0 Rifin ASFV_J13L PF05568.11 CBK23961.2 - 2 8.1 11.0 0.39 10.4 6.6 2.0 2 0 0 2 2 2 0 African swine fever virus J13L protein Collectrin PF16959.5 CBK23961.2 - 3.2 7.5 6.5 7 6.4 6.5 1.5 1 0 0 1 1 1 0 Renal amino acid transporter DNA_pol_B_2 PF03175.13 CBK23962.2 - 1.4e-15 57.1 13.0 4.9e-13 48.8 9.0 2.3 2 0 0 2 2 2 2 DNA polymerase type B, organellar and viral DUF1949 PF09186.11 CBK23963.2 - 0.0061 16.4 0.0 0.008 16.0 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1949) RRM_1 PF00076.22 CBK23965.2 - 2.2e-20 72.3 0.1 3e-20 71.8 0.1 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 CBK23965.2 - 1.9e-05 24.6 0.0 2.8e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Nup35_RRM PF05172.13 CBK23965.2 - 0.0043 17.0 0.0 0.0098 15.8 0.0 1.5 1 1 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.11 CBK23965.2 - 0.068 13.2 0.0 0.11 12.5 0.0 1.3 1 0 0 1 1 1 0 RNA binding motif Fra10Ac1 PF09725.9 CBK23966.2 - 4.1e-43 146.4 0.9 9.4e-43 145.3 0.9 1.6 1 0 0 1 1 1 1 Folate-sensitive fragile site protein Fra10Ac1 U62_UL91 PF17442.2 CBK23966.2 - 0.01 15.8 0.2 0.89 9.6 0.0 2.7 3 0 0 3 3 3 0 Functional domain of U62 and UL91 proteins RSS_P20 PF11757.8 CBK23966.2 - 0.012 16.1 0.9 0.012 16.1 0.9 2.2 2 0 0 2 2 2 0 Suppressor of RNA silencing P21-like N-terminal domain DUF4692 PF15763.5 CBK23966.2 - 0.98 9.9 10.9 1.6 9.1 9.4 1.9 2 0 0 2 2 2 0 Regulator of human erythroid cell expansion (RHEX) Ndc1_Nup PF09531.10 CBK23966.2 - 8.2 5.0 9.1 11 4.6 9.1 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Skp1_POZ PF03931.15 CBK23968.2 - 2.8e-05 24.2 0.5 0.00048 20.2 0.1 2.3 2 0 0 2 2 2 1 Skp1 family, tetramerisation domain Skp1 PF01466.19 CBK23968.2 - 0.00099 19.2 3.8 0.074 13.2 3.8 2.4 1 1 0 1 1 1 1 Skp1 family, dimerisation domain tRNA-synt_1f PF01921.18 CBK23968.2 - 0.025 13.5 0.0 0.029 13.3 0.0 1.2 1 0 0 1 1 1 0 tRNA synthetases class I (K) BTB PF00651.31 CBK23968.2 - 0.031 14.5 0.4 1.5 9.0 0.4 2.3 1 1 0 1 1 1 0 BTB/POZ domain EF-hand_7 PF13499.6 CBK23969.2 - 0.00062 20.2 4.9 0.0062 17.0 0.1 3.0 2 2 0 2 2 2 2 EF-hand domain pair EF-hand_4 PF12763.7 CBK23970.2 - 0.024 14.6 0.1 0.052 13.5 0.1 1.6 1 0 0 1 1 1 0 Cytoskeletal-regulatory complex EF hand PI3_PI4_kinase PF00454.27 CBK23971.2 - 1.9e-28 100.0 0.5 5.3e-26 92.0 0.4 2.2 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase DUF4135 PF13575.6 CBK23971.2 - 0.0013 18.2 0.1 0.0022 17.4 0.0 1.4 2 0 0 2 2 2 1 Domain of unknown function (DUF4135) DegV PF02645.16 CBK23971.2 - 0.12 11.7 0.0 0.21 10.9 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein, DegV family COG1307 zf-RING_9 PF13901.6 CBK23973.2 - 1.2e-30 107.1 1.3 2.4e-30 106.1 1.3 1.5 1 0 0 1 1 1 1 Putative zinc-RING and/or ribbon HC2 PF07382.11 CBK23973.2 - 4.8e-21 75.7 114.9 1.4e-06 28.5 39.7 3.8 1 1 3 4 4 4 4 Histone H1-like nucleoprotein HC2 PX PF00787.24 CBK23973.2 - 0.00026 20.9 0.5 0.00053 20.0 0.0 1.6 2 0 0 2 2 2 1 PX domain Adaptin_N PF01602.20 CBK23974.2 - 7.8e-81 272.2 1.7 1.1e-80 271.7 1.7 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 CBK23974.2 - 1.5e-13 51.1 3.1 3.5e-12 46.6 0.2 2.4 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 CBK23974.2 - 3.6e-06 27.3 0.0 0.086 13.2 0.0 3.4 3 1 1 4 4 4 3 HEAT repeats HEAT PF02985.22 CBK23974.2 - 0.00015 21.7 3.8 0.53 10.7 0.0 4.0 3 0 0 3 3 3 2 HEAT repeat SPG48 PF14764.6 CBK23974.2 - 0.00063 20.2 0.3 0.16 12.4 0.0 3.8 3 1 1 4 4 4 1 AP-5 complex subunit, vesicle trafficking RTP1_C1 PF10363.9 CBK23974.2 - 0.00087 19.5 1.8 4.3 7.6 0.1 4.9 2 2 0 3 3 3 1 Required for nuclear transport of RNA pol II C-terminus 1 HEAT_EZ PF13513.6 CBK23974.2 - 0.009 16.5 8.5 0.073 13.6 0.0 4.4 4 1 1 5 5 5 1 HEAT-like repeat Vac14_Fab1_bd PF12755.7 CBK23974.2 - 0.0094 16.5 2.0 0.81 10.3 0.3 2.7 2 0 0 2 2 2 1 Vacuolar 14 Fab1-binding region ParcG PF10274.9 CBK23974.2 - 0.13 12.3 0.2 3.6 7.7 0.0 2.4 1 1 1 2 2 2 0 Parkin co-regulated protein Lyase_1 PF00206.20 CBK23975.2 - 3.1e-89 299.5 0.0 1e-88 297.8 0.0 1.7 2 0 0 2 2 2 1 Lyase FumaraseC_C PF10415.9 CBK23975.2 - 1.3e-19 70.4 0.0 4e-19 68.8 0.0 1.9 1 0 0 1 1 1 1 Fumarase C C-terminus GalKase_gal_bdg PF10509.9 CBK23976.2 - 6.5e-17 60.8 0.1 1.5e-16 59.7 0.1 1.6 1 0 0 1 1 1 1 Galactokinase galactose-binding signature GHMP_kinases_N PF00288.26 CBK23976.2 - 2.6e-13 50.0 0.2 5.3e-13 49.0 0.2 1.6 1 0 0 1 1 1 1 GHMP kinases N terminal domain TBCC PF07986.12 CBK23977.2 - 2.3e-14 53.2 7.8 5.9e-14 51.8 7.8 1.8 1 1 0 1 1 1 1 Tubulin binding cofactor C Mod_r PF07200.13 CBK23978.2 - 0.073 13.2 0.2 0.11 12.7 0.2 1.2 1 0 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein SMC_N PF02463.19 CBK23979.2 - 3.8e-54 183.4 0.0 7.5e-54 182.5 0.0 1.6 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 CBK23979.2 - 2.9e-23 82.4 0.0 1.2e-22 80.4 0.0 2.2 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 CBK23979.2 - 2.1e-16 60.6 1.6 3.4e-08 33.7 0.2 3.1 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 CBK23979.2 - 9.4e-09 35.4 28.1 7.7e-07 29.1 9.3 4.1 2 2 1 3 3 3 2 AAA ATPase domain APG6_N PF17675.1 CBK23979.2 - 0.00025 21.6 16.2 0.00025 21.6 16.2 7.9 3 2 4 7 7 7 2 Apg6 coiled-coil region AAA_29 PF13555.6 CBK23979.2 - 0.0022 17.7 0.0 0.0047 16.6 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.6 CBK23979.2 - 0.0038 17.8 39.9 0.0038 17.8 39.9 6.4 2 2 1 3 3 3 1 AAA domain DDE_Tnp_4 PF13359.6 CBK23979.2 - 0.71 9.5 6.1 1.3 8.7 0.2 2.8 2 0 0 2 2 2 0 DDE superfamily endonuclease PRKCSH_1 PF13015.6 CBK23980.2 - 0.0068 16.1 0.0 0.011 15.4 0.0 1.4 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein SIR2 PF02146.17 CBK23981.2 - 9.2e-40 136.4 0.0 1.4e-39 135.8 0.0 1.3 1 0 0 1 1 1 1 Sir2 family TPP_enzyme_M PF00205.22 CBK23981.2 - 0.096 12.4 0.0 3.3 7.4 0.0 2.2 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain RNase_Zc3h12a PF11977.8 CBK23982.2 - 1.8e-24 86.3 0.0 2.6e-24 85.7 0.0 1.1 1 0 0 1 1 1 1 Zc3h12a-like Ribonuclease NYN domain PRORP PF16953.5 CBK23982.2 - 7.6e-05 22.3 0.0 0.00012 21.8 0.0 1.2 1 0 0 1 1 1 1 Protein-only RNase P AMP-binding PF00501.28 CBK23983.2 - 3.4e-84 282.9 0.8 4.4e-84 282.5 0.8 1.1 1 0 0 1 1 1 1 AMP-binding enzyme Cas_Cas2CT1978 PF09707.10 CBK23983.2 - 0.034 14.2 0.0 0.1 12.7 0.0 1.8 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Cas2CT1978) Hfx_Cass5 PF18287.1 CBK23983.2 - 0.075 13.2 0.0 0.16 12.2 0.0 1.6 1 0 0 1 1 1 0 Integron Cassette Protein Hfx_Cass5 Mannitol_dh_C PF08125.13 CBK23983.2 - 0.11 12.0 0.0 0.18 11.3 0.0 1.3 1 0 0 1 1 1 0 Mannitol dehydrogenase C-terminal domain Pkinase PF00069.25 CBK23984.2 - 5.8e-80 268.4 0.0 6.7e-80 268.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBK23984.2 - 1.8e-42 145.4 0.0 2.1e-42 145.2 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CBK23984.2 - 1.7e-06 27.6 0.0 2.7e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 CBK23984.2 - 0.00014 21.3 0.0 0.00019 20.8 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 CBK23984.2 - 0.00092 18.9 0.1 0.0014 18.3 0.1 1.2 1 0 0 1 1 1 1 RIO1 family YrbL-PhoP_reg PF10707.9 CBK23984.2 - 0.011 15.3 0.0 0.017 14.7 0.0 1.3 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Haspin_kinase PF12330.8 CBK23984.2 - 0.022 13.7 0.3 0.036 13.0 0.3 1.5 1 1 0 1 1 1 0 Haspin like kinase domain APH PF01636.23 CBK23984.2 - 0.047 13.6 0.1 0.17 11.7 0.1 1.8 1 1 0 2 2 2 0 Phosphotransferase enzyme family Choline_kinase PF01633.20 CBK23984.2 - 0.051 13.1 1.0 0.082 12.5 0.1 1.7 2 0 0 2 2 2 0 Choline/ethanolamine kinase Pox_ser-thr_kin PF05445.11 CBK23984.2 - 0.19 10.7 1.4 1.5 7.7 0.1 2.0 2 0 0 2 2 2 0 Poxvirus serine/threonine protein kinase Polysacc_deac_1 PF01522.21 CBK23985.2 - 2.3e-11 43.6 0.6 6.4e-11 42.2 0.6 1.8 1 1 0 1 1 1 1 Polysaccharide deacetylase Glyco_hydro_57 PF03065.15 CBK23985.2 - 0.0056 15.9 0.1 0.014 14.6 0.1 1.8 1 1 0 1 1 1 1 Glycosyl hydrolase family 57 Ribosomal_L35Ae PF01247.18 CBK23987.2 - 8.2e-39 131.7 1.2 9.3e-39 131.5 1.2 1.0 1 0 0 1 1 1 1 Ribosomal protein L35Ae Ribosomal_L38e PF01781.18 CBK23988.2 - 1.9e-30 104.8 2.9 2.1e-30 104.6 2.9 1.0 1 0 0 1 1 1 1 Ribosomal L38e protein family Acyltransferase PF01553.21 CBK23989.2 - 2.7e-15 56.2 0.0 5.6e-15 55.2 0.0 1.5 1 0 0 1 1 1 1 Acyltransferase Acyltransf_C PF16076.5 CBK23989.2 - 1.9e-09 37.5 0.1 1.3e-08 34.8 0.0 2.2 2 0 0 2 2 2 1 Acyltransferase C-terminus SANTA PF09133.10 CBK23990.2 - 5.5e-22 78.1 0.0 1.1e-21 77.2 0.0 1.5 1 0 0 1 1 1 1 SANTA (SANT Associated) PHD PF00628.29 CBK23990.2 - 5.1e-06 26.3 7.4 1.4e-05 24.9 7.4 1.8 1 0 0 1 1 1 1 PHD-finger zf-PHD-like PF15446.6 CBK23990.2 - 0.0012 18.5 6.2 0.55 9.8 0.1 2.5 1 1 1 2 2 2 2 PHD/FYVE-zinc-finger like domain PHD_2 PF13831.6 CBK23990.2 - 0.0085 15.6 2.2 0.0085 15.6 2.2 2.0 2 0 0 2 2 2 1 PHD-finger EIN3 PF04873.13 CBK23991.2 - 0.043 13.1 0.0 0.046 13.0 0.0 1.1 1 0 0 1 1 1 0 Ethylene insensitive 3 WG_beta_rep PF14903.6 CBK23991.2 - 0.056 13.7 0.0 0.077 13.3 0.0 1.3 1 0 0 1 1 1 0 WG containing repeat DnaJ_C PF01556.18 CBK23993.2 - 3.1e-40 137.7 0.1 4.6e-40 137.1 0.1 1.3 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 CBK23993.2 - 4.3e-22 78.0 2.4 8.1e-22 77.1 2.4 1.5 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 CBK23993.2 - 4.1e-16 59.1 12.3 9.9e-16 57.9 12.3 1.7 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 CBK23993.2 - 8.8e-07 28.8 6.6 6.9e-05 22.7 0.9 2.5 2 0 0 2 2 2 2 Tryptophan RNA-binding attenuator protein inhibitory protein Cytochrome_CBB3 PF13442.6 CBK23993.2 - 0.065 13.6 5.9 2 8.8 0.0 3.0 2 1 0 2 2 2 0 Cytochrome C oxidase, cbb3-type, subunit III zf-RING_9 PF13901.6 CBK23993.2 - 0.87 9.5 6.7 2.8 7.9 0.2 2.4 1 1 1 2 2 2 0 Putative zinc-RING and/or ribbon Acetyltransf_3 PF13302.7 CBK23994.2 - 4e-05 24.3 0.0 6.6e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 CBK23994.2 - 0.0015 18.8 0.0 0.0025 18.0 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family DUF4372 PF14294.6 CBK23994.2 - 0.069 13.3 0.0 0.2 11.8 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4372) RNA_pol_Rpb1_1 PF04997.12 CBK23995.2 - 6.6e-76 255.6 0.0 3.3e-75 253.3 0.0 2.1 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_2 PF00623.20 CBK23995.2 - 1.3e-70 237.0 0.1 2.5e-70 236.0 0.1 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_5 PF04998.17 CBK23995.2 - 4.7e-66 223.0 0.0 1.3e-65 221.5 0.0 1.7 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_6 PF04992.14 CBK23995.2 - 3.9e-55 186.6 0.9 3.9e-55 186.6 0.9 2.0 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 6 RNA_pol_Rpb1_3 PF04983.18 CBK23995.2 - 9.5e-43 145.8 1.4 3.5e-42 144.0 0.1 2.6 3 0 0 3 3 3 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.17 CBK23995.2 - 1.8e-28 98.6 0.2 3.8e-28 97.6 0.2 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_7 PF04990.12 CBK23995.2 - 1.2e-21 77.1 0.1 3.2e-21 75.7 0.1 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 7 Baculo_PEP_C PF04513.12 CBK23995.2 - 0.0015 18.6 0.0 0.8 9.7 0.0 3.7 3 1 1 4 4 4 1 Baculovirus polyhedron envelope protein, PEP, C terminus CxC7 PF18866.1 CBK23995.2 - 0.0068 16.5 1.0 1.8 8.8 0.2 3.1 3 0 0 3 3 3 1 CxC7 like cysteine cluster associated with KDZ transposases HSP70 PF00012.20 CBK23996.2 - 1e-11 43.8 0.3 8e-11 40.8 0.1 2.1 1 1 1 2 2 2 1 Hsp70 protein BcrAD_BadFG PF01869.20 CBK23996.2 - 0.0012 18.4 0.0 0.45 10.0 0.0 2.5 2 0 0 2 2 2 2 BadF/BadG/BcrA/BcrD ATPase family Thioredoxin_13 PF18401.1 CBK23996.2 - 0.031 14.2 0.3 0.068 13.1 0.3 1.5 1 0 0 1 1 1 0 Thioredoxin-like domain FmdE PF02663.14 CBK23996.2 - 0.047 13.7 0.2 0.26 11.3 0.0 2.1 2 0 0 2 2 2 0 FmdE, Molybdenum formylmethanofuran dehydrogenase operon Phospholip_A2_1 PF00068.19 CBK23996.2 - 0.072 13.6 0.7 0.16 12.5 0.7 1.5 1 0 0 1 1 1 0 Phospholipase A2 DUF4171 PF13775.6 CBK23996.2 - 0.16 12.4 0.6 0.28 11.6 0.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4171) Prp19 PF08606.11 CBK23997.2 - 2.1e-35 120.5 0.6 4.6e-35 119.4 0.6 1.6 1 0 0 1 1 1 1 Prp19/Pso4-like WD40 PF00400.32 CBK23997.2 - 2.2e-28 97.9 0.1 5.4e-05 23.9 0.0 7.0 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBK23997.2 - 1.1e-14 54.5 0.1 8.4e-05 22.8 0.0 5.1 2 1 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain zf-Nse PF11789.8 CBK23997.2 - 5e-05 23.0 0.0 9.5e-05 22.1 0.0 1.5 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit Nup160 PF11715.8 CBK23997.2 - 8.7e-05 21.3 2.0 0.23 10.0 0.0 3.7 2 2 1 3 3 3 2 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.16 CBK23997.2 - 0.00011 20.8 0.1 0.49 8.9 0.0 3.2 1 1 2 3 3 3 2 Cytochrome D1 heme domain Ge1_WD40 PF16529.5 CBK23997.2 - 0.00063 18.8 0.0 0.49 9.3 0.0 2.6 1 1 1 2 2 2 2 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 CBK23997.2 - 0.0022 17.9 0.0 0.12 12.3 0.0 2.8 1 1 2 3 3 3 1 Eukaryotic translation initiation factor eIF2A Ret2_MD PF18528.1 CBK23997.2 - 0.0065 16.8 0.0 0.023 15.1 0.0 1.9 2 0 0 2 2 2 1 RNA editing 3' terminal uridylyl transferase 2 middle domain zf-NOSIP PF15906.5 CBK23997.2 - 0.053 13.7 0.0 0.12 12.6 0.0 1.6 1 0 0 1 1 1 0 Zinc-finger of nitric oxide synthase-interacting protein Na_sulph_symp PF00939.19 CBK23998.2 - 1.1e-69 235.7 28.1 1.4e-69 235.4 28.1 1.0 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CitMHS PF03600.16 CBK23998.2 - 1.7e-37 129.3 49.8 6.7e-28 97.7 22.9 2.2 1 1 1 2 2 2 2 Citrate transporter DctM PF06808.12 CBK23998.2 - 0.00023 20.1 2.8 0.00023 20.1 2.8 2.6 3 0 0 3 3 3 2 Tripartite ATP-independent periplasmic transporter, DctM component Zip PF02535.22 CBK23999.2 - 4.7e-25 88.5 7.4 6.1e-25 88.1 7.4 1.2 1 0 0 1 1 1 1 ZIP Zinc transporter RseC_MucC PF04246.12 CBK23999.2 - 0.034 14.1 0.0 0.034 14.1 0.0 2.0 2 1 0 2 2 2 0 Positive regulator of sigma(E), RseC/MucC DEAD PF00270.29 CBK24000.2 - 7.9e-12 45.3 0.0 1.1e-11 44.9 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_16 PF13191.6 CBK24000.2 - 0.0002 21.8 0.0 0.00031 21.2 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain ResIII PF04851.15 CBK24000.2 - 0.00051 20.1 0.0 0.00088 19.3 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit T2SSE PF00437.20 CBK24000.2 - 0.001 18.2 0.0 0.0015 17.7 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_19 PF13245.6 CBK24000.2 - 0.0076 16.6 0.0 0.012 15.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 CBK24000.2 - 0.011 16.0 0.0 0.018 15.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 CBK24000.2 - 0.055 13.2 0.0 0.069 12.9 0.0 1.2 1 0 0 1 1 1 0 AAA domain UvrD-helicase PF00580.21 CBK24000.2 - 0.064 12.8 0.2 0.15 11.6 0.0 1.7 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain Helicase_C PF00271.31 CBK24001.2 - 1.2e-07 32.0 0.0 6.5e-07 29.7 0.0 2.2 1 1 0 1 1 1 1 Helicase conserved C-terminal domain XG_FTase PF03254.13 CBK24002.2 - 4.4e-05 22.3 0.0 7.3e-05 21.6 0.0 1.3 1 1 0 1 1 1 1 Xyloglucan fucosyltransferase NodZ PF05830.11 CBK24002.2 - 0.0013 17.6 0.0 0.0017 17.3 0.0 1.1 1 0 0 1 1 1 1 Nodulation protein Z (NodZ) O-FucT PF10250.9 CBK24002.2 - 0.046 13.4 0.0 0.063 13.0 0.0 1.1 1 0 0 1 1 1 0 GDP-fucose protein O-fucosyltransferase ER_lumen_recept PF00810.18 CBK24003.2 - 1.6e-36 126.4 6.4 1.6e-36 126.4 6.4 2.2 3 0 0 3 3 3 1 ER lumen protein retaining receptor MRAP PF15183.6 CBK24003.2 - 0.11 12.4 0.5 0.11 12.4 0.5 2.2 2 0 0 2 2 2 0 Melanocortin-2 receptor accessory protein family Trypan_PARP PF05887.11 CBK24004.2 - 0.019 14.9 37.3 0.019 14.9 37.3 4.3 2 1 2 4 4 4 0 Procyclic acidic repetitive protein (PARP) Fer2_3 PF13085.6 CBK24005.2 - 4.5e-33 113.5 0.0 8e-33 112.7 0.0 1.4 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer4_17 PF13534.6 CBK24005.2 - 1.7e-08 34.9 6.5 1.7e-08 34.9 6.5 2.1 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_8 PF13183.6 CBK24005.2 - 2.7e-08 34.2 8.1 2.7e-08 34.2 8.1 2.3 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_10 PF13237.6 CBK24005.2 - 2.3e-07 30.8 3.4 2.3e-07 30.8 3.4 2.2 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer2 PF00111.27 CBK24005.2 - 0.00035 20.5 0.4 0.00035 20.5 0.4 2.0 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fer4_7 PF12838.7 CBK24005.2 - 0.0033 18.0 5.1 0.0033 18.0 5.1 2.6 2 2 0 2 2 2 1 4Fe-4S dicluster domain Fer4_9 PF13187.6 CBK24005.2 - 0.031 14.4 8.2 0.031 14.4 8.2 2.6 2 1 0 2 2 2 0 4Fe-4S dicluster domain Herpes_UL51 PF04540.13 CBK24005.2 - 0.11 12.3 0.0 0.18 11.5 0.0 1.3 1 0 0 1 1 1 0 Herpesvirus UL51 protein Methyltransf_25 PF13649.6 CBK24006.2 - 7.7e-06 26.5 0.0 1.1e-05 26.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CBK24006.2 - 8.7e-05 23.1 0.0 0.00013 22.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 CBK24006.2 - 0.00033 20.1 0.0 0.00048 19.5 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 CBK24006.2 - 0.0057 17.4 0.0 0.0083 16.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain CSN8_PSD8_EIF3K PF10075.9 CBK24007.2 - 3.7e-15 56.2 0.0 5.7e-15 55.5 0.0 1.3 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family RE_SinI PF09570.10 CBK24007.2 - 0.11 11.7 0.1 0.22 10.7 0.0 1.6 1 1 1 2 2 2 0 SinI restriction endonuclease DEAD PF00270.29 CBK24008.2 - 5e-49 166.4 0.2 1.4e-48 164.9 0.2 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CBK24008.2 - 2e-26 92.5 0.0 2.9e-25 88.8 0.0 2.7 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 CBK24008.2 - 8.1e-18 64.4 0.4 2.6e-17 62.8 0.1 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4217) ResIII PF04851.15 CBK24008.2 - 1.2e-05 25.4 0.0 2.5e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SecA_DEAD PF07517.14 CBK24008.2 - 0.028 13.7 0.0 0.083 12.2 0.0 1.7 1 1 0 1 1 1 0 SecA DEAD-like domain Salt_tol_Pase PF09506.10 CBK24008.2 - 0.039 12.7 0.0 0.067 12.0 0.0 1.3 1 0 0 1 1 1 0 Glucosylglycerol-phosphate phosphatase (Salt_tol_Pase) RelE PF06296.12 CBK24008.2 - 0.12 12.5 0.3 2.3 8.4 0.1 2.9 1 1 1 2 2 2 0 RelE toxin of RelE / RelB toxin-antitoxin system Nop10p PF04135.12 CBK24010.2 - 1.4e-23 82.6 0.8 1.6e-23 82.4 0.8 1.1 1 0 0 1 1 1 1 Nucleolar RNA-binding protein, Nop10p family zf-CCCH PF00642.24 CBK24011.2 - 8.3e-06 25.6 3.6 1.7e-05 24.6 1.2 2.2 2 0 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 CBK24011.2 - 0.00017 22.3 0.5 0.00028 21.5 0.5 1.4 1 1 1 2 2 2 1 Torus domain zf-CCCH_4 PF18044.1 CBK24011.2 - 0.00037 20.2 2.2 0.00046 19.9 0.5 1.9 2 0 0 2 2 2 1 CCCH-type zinc finger zf_CCCH_4 PF18345.1 CBK24011.2 - 0.0056 16.7 3.5 0.0056 16.7 3.5 2.3 2 0 0 2 2 2 1 Zinc finger domain Ribosomal_S7e PF01251.18 CBK24012.2 - 3.5e-65 219.2 1.0 3.9e-65 219.0 1.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S7e SHIPPO-rpt PF07004.12 CBK24013.2 - 4.4e-33 112.7 135.8 3.9 8.6 0.1 31.7 1 1 30 31 31 31 29 Sperm-tail PG-rich repeat Ran_BP1 PF00638.18 CBK24013.2 - 6.7e-05 23.1 0.2 0.00013 22.3 0.2 1.3 1 0 0 1 1 1 1 RanBP1 domain phage_tail_N PF08400.10 CBK24013.2 - 0.003 17.5 23.7 47 4.0 0.1 9.5 1 1 15 16 16 16 0 Prophage tail fibre N-terminal BppU_N PF10651.9 CBK24013.2 - 2.1 8.1 24.2 3.2e+02 1.0 0.0 10.5 2 1 16 19 19 19 0 BppU N-terminal domain Myb_DNA-binding PF00249.31 CBK24014.2 - 3.1e-30 104.1 4.1 2.2e-16 59.7 0.6 2.2 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 CBK24014.2 - 5.9e-22 77.7 0.6 5.5e-14 52.2 0.1 2.3 1 1 1 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 CBK24014.2 - 0.00024 21.1 0.1 0.002 18.1 0.0 2.0 1 1 1 2 2 2 1 SLIDE Myb_DNA-bind_7 PF15963.5 CBK24014.2 - 0.00093 19.1 0.2 2 8.4 0.3 2.2 2 0 0 2 2 2 2 Myb DNA-binding like Sec23_trunk PF04811.15 CBK24015.2 - 7e-56 189.5 0.1 9.8e-56 189.0 0.1 1.2 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain zf-Sec23_Sec24 PF04810.15 CBK24015.2 - 4.8e-15 55.3 3.6 1.2e-14 54.1 3.6 1.6 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Sec23_helical PF04815.15 CBK24015.2 - 7.5e-15 54.6 0.3 7.5e-15 54.6 0.3 1.8 2 0 0 2 2 2 1 Sec23/Sec24 helical domain Sec23_BS PF08033.12 CBK24015.2 - 1.2e-11 45.1 0.0 2.3e-11 44.2 0.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain Gelsolin PF00626.22 CBK24015.2 - 0.00098 19.0 0.0 0.002 18.0 0.0 1.5 1 0 0 1 1 1 1 Gelsolin repeat VWA_2 PF13519.6 CBK24015.2 - 0.0019 18.8 0.1 1.7 9.3 0.0 2.4 2 0 0 2 2 2 2 von Willebrand factor type A domain MRP-L28 PF09812.9 CBK24016.2 - 0.0071 16.5 4.0 0.0085 16.2 4.0 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L28 Fib_alpha PF08702.10 CBK24016.2 - 0.012 15.8 5.4 0.017 15.3 5.4 1.3 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Herpes_UL6 PF01763.16 CBK24016.2 - 0.015 13.9 3.9 0.017 13.7 3.9 1.1 1 0 0 1 1 1 0 Herpesvirus UL6 like FAM76 PF16046.5 CBK24016.2 - 0.017 14.5 4.8 0.022 14.2 4.8 1.2 1 0 0 1 1 1 0 FAM76 protein GAS PF13851.6 CBK24016.2 - 0.039 13.3 12.3 0.049 13.0 12.3 1.0 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding LRS4 PF10422.9 CBK24016.2 - 0.082 12.5 2.3 0.088 12.4 2.3 1.1 1 0 0 1 1 1 0 Monopolin complex subunit LRS4 Ima1_N PF09779.9 CBK24016.2 - 0.18 12.7 3.9 0.25 12.2 3.9 1.2 1 0 0 1 1 1 0 Ima1 N-terminal domain TMF_DNA_bd PF12329.8 CBK24016.2 - 0.59 10.2 9.7 4.4 7.4 0.4 2.1 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding APG6_N PF17675.1 CBK24016.2 - 1.4 9.4 12.7 3.2 8.3 12.7 1.5 1 1 0 1 1 1 0 Apg6 coiled-coil region DUF3450 PF11932.8 CBK24016.2 - 1.5 8.1 11.8 5.1 6.3 11.8 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3450) PRP1_N PF06424.12 CBK24016.2 - 2.1 8.8 8.0 2.6 8.4 8.0 1.1 1 0 0 1 1 1 0 PRP1 splicing factor, N-terminal Tup_N PF08581.10 CBK24016.2 - 2.7 8.4 16.1 14 6.1 5.0 2.9 1 1 0 2 2 2 0 Tup N-terminal SlyX PF04102.12 CBK24016.2 - 4.9 7.9 9.4 14 6.4 0.4 2.4 1 1 1 2 2 2 0 SlyX PMSR PF01625.21 CBK24017.2 - 2.4e-14 53.8 12.9 3.9e-12 46.6 8.5 2.5 1 1 1 2 2 2 2 Peptide methionine sulfoxide reductase MAD PF05557.13 CBK24018.2 - 0.003 16.0 17.4 0.003 16.0 17.4 3.8 2 1 3 5 5 5 1 Mitotic checkpoint protein Biotin_carb_C PF02785.19 CBK24018.2 - 0.05 13.7 3.1 1.7 8.8 0.1 3.0 2 1 1 3 3 3 0 Biotin carboxylase C-terminal domain Nucleoporin_FG PF13634.6 CBK24018.2 - 0.13 13.1 3.2 0.39 11.6 3.2 1.8 1 0 0 1 1 1 0 Nucleoporin FG repeat region NTP_transf_4 PF13562.6 CBK24018.2 - 0.16 12.1 6.7 6.1 7.0 0.2 3.2 2 1 0 2 2 2 0 Sugar nucleotidyl transferase SGT1 PF07093.11 CBK24019.2 - 1.2e-30 106.6 0.0 1.3e-30 106.5 0.0 1.0 1 0 0 1 1 1 1 SGT1 protein Rdx PF10262.9 CBK24020.2 - 2.7e-05 24.2 0.1 3.7e-05 23.8 0.1 1.4 1 1 0 1 1 1 1 Rdx family Syntaxin PF00804.25 CBK24021.2 - 2.6e-07 30.5 7.2 3e-07 30.3 7.2 1.0 1 0 0 1 1 1 1 Syntaxin Apolipoprotein PF01442.18 CBK24021.2 - 1.3e-05 25.1 5.7 1.9e-05 24.6 5.7 1.2 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain AAA_13 PF13166.6 CBK24021.2 - 2.1e-05 23.4 9.2 2.6e-05 23.1 9.2 1.0 1 0 0 1 1 1 1 AAA domain Atg14 PF10186.9 CBK24021.2 - 0.00033 19.8 6.4 0.00037 19.7 6.4 1.1 1 0 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 BMFP PF04380.13 CBK24021.2 - 0.00064 20.1 0.9 0.36 11.4 0.3 2.6 2 1 0 2 2 2 1 Membrane fusogenic activity Mitofilin PF09731.9 CBK24021.2 - 0.0024 16.8 9.4 0.0028 16.6 9.4 1.1 1 0 0 1 1 1 1 Mitochondrial inner membrane protein Collagen_mid PF15984.5 CBK24021.2 - 0.0051 16.6 0.1 1.6 8.5 0.1 2.1 1 1 1 2 2 2 1 Bacterial collagen, middle region RINT1_TIP1 PF04437.13 CBK24021.2 - 0.0065 15.4 1.5 0.014 14.3 0.1 1.8 1 1 1 2 2 2 1 RINT-1 / TIP-1 family Baculo_PEP_C PF04513.12 CBK24021.2 - 0.012 15.7 7.9 0.043 13.9 7.9 1.9 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus BLYB PF05289.11 CBK24021.2 - 0.016 15.4 6.5 0.021 15.1 3.6 2.2 1 1 0 2 2 2 0 Borrelia hemolysin accessory protein AAA_32 PF13654.6 CBK24021.2 - 0.022 13.6 4.7 0.026 13.4 4.7 1.1 1 0 0 1 1 1 0 AAA domain RPN7 PF10602.9 CBK24021.2 - 0.022 14.5 3.8 0.036 13.8 2.9 1.7 1 1 0 1 1 1 0 26S proteasome subunit RPN7 LMBR1 PF04791.16 CBK24021.2 - 0.023 13.6 6.3 0.026 13.5 6.3 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein Hemagglutinin PF00509.18 CBK24021.2 - 0.025 13.0 5.3 0.028 12.8 5.3 1.0 1 0 0 1 1 1 0 Haemagglutinin CdvA PF18822.1 CBK24021.2 - 0.028 14.3 0.7 0.028 14.3 0.7 2.6 1 1 2 3 3 3 0 CdvA-like coiled-coil domain DASH_Spc19 PF08287.11 CBK24021.2 - 0.031 14.2 6.8 0.06 13.2 6.6 1.7 1 1 0 1 1 1 0 Spc19 ApoLp-III PF07464.11 CBK24021.2 - 0.035 14.2 11.9 0.045 13.8 11.9 1.3 1 1 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) YtxH PF12732.7 CBK24021.2 - 0.036 14.6 7.3 1.9 9.1 0.1 2.2 2 0 0 2 2 2 0 YtxH-like protein OmpH PF03938.14 CBK24021.2 - 0.042 14.2 7.0 0.061 13.7 7.0 1.4 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) SF-assemblin PF06705.11 CBK24021.2 - 0.055 12.8 10.9 0.16 11.3 10.9 1.4 1 1 0 1 1 1 0 SF-assemblin/beta giardin LemA PF04011.12 CBK24021.2 - 0.058 13.3 3.7 0.44 10.4 3.7 2.3 1 1 0 1 1 1 0 LemA family Prominin PF05478.11 CBK24021.2 - 0.063 11.2 7.7 0.086 10.8 7.0 1.4 1 1 0 1 1 1 0 Prominin DUF4094 PF13334.6 CBK24021.2 - 0.063 13.7 3.9 1.7 9.1 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4094) Vps4_C PF09336.10 CBK24021.2 - 0.077 13.0 1.0 2.7 8.1 1.0 2.5 1 1 0 1 1 1 0 Vps4 C terminal oligomerisation domain Nas2_N PF18265.1 CBK24021.2 - 0.081 12.9 0.7 0.081 12.9 0.7 2.3 3 1 0 3 3 3 0 Nas2 N_terminal domain Exo84_C PF16528.5 CBK24021.2 - 0.082 12.7 4.8 0.12 12.2 4.8 1.3 1 0 0 1 1 1 0 Exocyst component 84 C-terminal Syntaxin_2 PF14523.6 CBK24021.2 - 0.089 13.2 10.1 0.077 13.4 8.5 1.9 1 1 1 2 2 2 0 Syntaxin-like protein Trimer_CC PF08954.11 CBK24021.2 - 0.1 12.2 1.6 7.8 6.1 0.0 3.2 3 0 0 3 3 3 0 Trimerisation motif Mod_r PF07200.13 CBK24021.2 - 0.1 12.7 9.3 0.23 11.6 9.3 1.6 1 1 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein CorA PF01544.18 CBK24021.2 - 0.13 11.6 3.3 0.57 9.5 0.9 2.0 1 1 1 2 2 2 0 CorA-like Mg2+ transporter protein KapB PF08810.10 CBK24021.2 - 0.14 12.3 3.9 4 7.6 0.1 2.2 1 1 1 2 2 2 0 Kinase associated protein B Spore_III_AB PF09548.10 CBK24021.2 - 0.16 12.1 1.3 0.29 11.2 1.2 1.6 1 1 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) ZapB PF06005.12 CBK24021.2 - 0.16 12.4 7.2 1.2 9.7 4.2 2.9 2 1 0 2 2 2 0 Cell division protein ZapB Snapin_Pallidin PF14712.6 CBK24021.2 - 0.19 12.2 10.7 6.4 7.3 7.1 3.2 1 1 2 3 3 3 0 Snapin/Pallidin TCTP PF00838.17 CBK24021.2 - 0.19 12.0 7.3 7.4 6.9 0.1 2.1 1 1 1 2 2 2 0 Translationally controlled tumour protein DUF4298 PF14131.6 CBK24021.2 - 0.2 11.6 5.0 1.7 8.7 0.2 2.8 3 1 0 3 3 3 0 Domain of unknown function (DUF4298) AI-2E_transport PF01594.16 CBK24021.2 - 0.21 10.7 0.7 0.26 10.4 0.7 1.3 1 0 0 1 1 1 0 AI-2E family transporter PIN_8 PF18476.1 CBK24021.2 - 0.23 11.3 7.7 0.69 9.7 7.6 1.7 1 1 0 1 1 1 0 PIN like domain Syntaxin-6_N PF09177.11 CBK24021.2 - 0.29 11.7 7.0 0.82 10.3 6.0 2.0 1 1 1 2 2 2 0 Syntaxin 6, N-terminal Lipase_GDSL_3 PF14606.6 CBK24021.2 - 0.3 11.2 4.4 1.1 9.4 4.4 1.8 1 1 1 2 2 2 0 GDSL-like Lipase/Acylhydrolase family DUF2120 PF09893.9 CBK24021.2 - 0.36 10.9 4.0 0.75 9.9 3.4 1.8 1 1 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2120) SAM_Exu PF18609.1 CBK24021.2 - 0.38 10.9 2.2 0.74 10.0 0.4 2.2 2 1 0 2 2 2 0 Exuperantia SAM-like domain DUF1664 PF07889.12 CBK24021.2 - 0.43 10.6 9.5 1.9 8.6 9.1 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) DUF2203 PF09969.9 CBK24021.2 - 0.7 10.6 4.8 2.4 8.9 3.6 2.1 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) TMF_DNA_bd PF12329.8 CBK24021.2 - 0.71 9.9 10.1 2.8 8.0 0.4 3.1 1 1 2 3 3 3 0 TATA element modulatory factor 1 DNA binding Fib_alpha PF08702.10 CBK24021.2 - 0.95 9.6 13.2 1 9.5 11.4 1.7 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Uso1_p115_C PF04871.13 CBK24021.2 - 1 9.8 9.7 2.8 8.3 9.7 1.9 1 1 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region LCIB_C_CA PF18599.1 CBK24021.2 - 1.3 8.2 6.9 2.2 7.5 4.8 1.8 1 1 1 2 2 2 0 Limiting CO2-inducible proteins B/C beta carbonyic anhydrases DUF4795 PF16043.5 CBK24021.2 - 1.7 8.2 10.8 42 3.7 10.7 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) Allexi_40kDa PF05549.11 CBK24021.2 - 2.2 7.7 7.7 3.9 6.9 4.6 1.7 1 1 0 1 1 1 0 Allexivirus 40kDa protein DUF4407 PF14362.6 CBK24021.2 - 2.4 7.4 6.2 5.3 6.3 6.2 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) bZIP_1 PF00170.21 CBK24021.2 - 3.3 7.9 6.8 5.3 7.2 0.1 2.7 3 0 0 3 3 2 0 bZIP transcription factor DUF948 PF06103.11 CBK24021.2 - 3.8 7.8 9.6 3e+02 1.7 9.6 2.6 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) LPP PF04728.13 CBK24021.2 - 6.4 7.3 11.1 1.6 9.2 0.9 3.4 2 1 2 4 4 3 0 Lipoprotein leucine-zipper SNARE PF05739.19 CBK24022.2 - 6.9e-12 45.2 4.3 9.2e-12 44.8 4.3 1.2 1 0 0 1 1 1 1 SNARE domain GPDPase_memb PF10110.9 CBK24022.2 - 0.00083 18.2 0.1 0.00093 18.1 0.1 1.1 1 0 0 1 1 1 1 Membrane domain of glycerophosphoryl diester phosphodiesterase DUF2207 PF09972.9 CBK24022.2 - 0.0022 16.9 0.1 0.0022 16.8 0.1 1.0 1 0 0 1 1 1 1 Predicted membrane protein (DUF2207) DUF3671 PF12420.8 CBK24022.2 - 0.0032 17.5 1.5 0.0039 17.3 1.5 1.1 1 0 0 1 1 1 1 Protein of unknown function Fusion_gly PF00523.18 CBK24022.2 - 0.0039 15.5 2.9 0.0049 15.2 2.9 1.0 1 0 0 1 1 1 1 Fusion glycoprotein F0 Orf78 PF06024.12 CBK24022.2 - 0.013 15.8 0.4 0.014 15.7 0.4 1.1 1 0 0 1 1 1 0 Orf78 (ac78) DUF1676 PF07898.13 CBK24022.2 - 0.023 14.7 0.0 0.024 14.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1676) ETRAMP PF09716.10 CBK24022.2 - 0.035 14.2 4.8 0.077 13.1 4.7 1.7 1 1 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) DUF5383 PF17355.2 CBK24022.2 - 0.085 13.2 0.2 0.1 13.0 0.2 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5383) DUF5113 PF17140.4 CBK24022.2 - 0.1 12.4 0.1 0.11 12.3 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5113) CwsA PF10814.8 CBK24022.2 - 0.12 12.6 0.2 0.14 12.4 0.2 1.1 1 0 0 1 1 1 0 Cell wall synthesis protein CwsA DUF5345 PF17280.2 CBK24022.2 - 0.13 12.3 1.6 0.2 11.6 1.4 1.4 1 1 0 1 1 1 0 Family of unknown function (DUF5345) Mit_KHE1 PF10173.9 CBK24022.2 - 0.15 12.2 0.0 0.17 11.9 0.0 1.0 1 0 0 1 1 1 0 Mitochondrial K+-H+ exchange-related Syntaxin PF00804.25 CBK24022.2 - 0.23 11.1 4.4 2.7 7.6 0.4 2.0 2 0 0 2 2 2 0 Syntaxin EVI2A PF05399.11 CBK24022.2 - 0.46 10.0 2.8 0.48 10.0 2.8 1.0 1 0 0 1 1 1 0 Ectropic viral integration site 2A protein (EVI2A) UPF0258 PF06789.12 CBK24022.2 - 0.67 10.1 5.0 0.81 9.8 5.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0258) Herpes_US9 PF06072.11 CBK24022.2 - 3.7 7.5 5.4 6.8 6.6 5.5 1.4 1 1 0 1 1 1 0 Alphaherpesvirus tegument protein US9 Ribosomal_60s PF00428.19 CBK24023.2 - 1.6e-15 57.5 15.0 1.8e-15 57.3 15.0 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein DUF3824 PF12868.7 CBK24023.2 - 0.0059 17.3 2.0 0.0067 17.1 2.0 1.0 1 0 0 1 1 1 1 Domain of unknwon function (DUF3824) FYDLN_acid PF09538.10 CBK24023.2 - 0.041 14.5 4.4 0.045 14.4 4.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) Myc_N PF01056.18 CBK24023.2 - 0.14 12.1 3.8 0.14 12.0 3.8 1.1 1 0 0 1 1 1 0 Myc amino-terminal region OCC1 PF15506.6 CBK24023.2 - 0.21 11.7 3.1 0.29 11.3 3.1 1.2 1 0 0 1 1 1 0 OCC1 family DNA_pol_phi PF04931.13 CBK24023.2 - 0.21 9.6 3.6 0.18 9.8 3.6 1.0 1 0 0 1 1 1 0 DNA polymerase phi Cytomega_UL84 PF06284.11 CBK24023.2 - 0.32 9.4 3.7 0.31 9.5 3.7 1.0 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein MscS_TM PF12794.7 CBK24023.2 - 6 5.6 5.1 6.9 5.4 5.1 1.1 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 GMP_synt_C PF00958.22 CBK24024.2 - 6.6e-43 144.7 0.0 1.6e-42 143.4 0.0 1.7 1 0 0 1 1 1 1 GMP synthase C terminal domain GATase PF00117.28 CBK24024.2 - 2.4e-34 118.8 0.0 3.5e-34 118.2 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I NAD_synthase PF02540.17 CBK24024.2 - 2.9e-09 36.4 0.1 4.3e-05 22.7 0.1 2.4 2 0 0 2 2 2 2 NAD synthase Peptidase_C26 PF07722.13 CBK24024.2 - 1.3e-06 28.4 0.2 4e-06 26.7 0.2 1.9 1 1 0 1 1 1 1 Peptidase C26 tRNA_Me_trans PF03054.16 CBK24024.2 - 0.0008 18.3 0.3 0.0035 16.2 0.2 1.9 2 0 0 2 2 2 1 tRNA methyl transferase ThiI PF02568.14 CBK24024.2 - 0.0046 16.6 0.1 0.012 15.2 0.1 1.7 2 0 0 2 2 2 1 Thiamine biosynthesis protein (ThiI) SNO PF01174.19 CBK24024.2 - 0.0077 16.1 0.0 0.071 13.0 0.0 2.2 2 0 0 2 2 2 1 SNO glutamine amidotransferase family QueC PF06508.13 CBK24024.2 - 0.018 14.5 0.0 0.79 9.2 0.0 2.2 1 1 0 1 1 1 0 Queuosine biosynthesis protein QueC DUF5550 PF17704.1 CBK24025.2 - 0.02 15.0 0.2 0.026 14.7 0.2 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5550) Hexapep PF00132.24 CBK24026.2 - 2.1e-10 39.9 16.0 2.7e-06 26.9 6.3 4.1 2 1 1 4 4 4 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 CBK24026.2 - 3.8e-07 29.7 15.9 0.00056 19.6 2.7 2.9 2 1 1 3 3 3 2 Hexapeptide repeat of succinyl-transferase Fucokinase PF07959.12 CBK24026.2 - 0.26 10.2 0.9 0.42 9.5 0.9 1.4 1 1 0 1 1 1 0 L-fucokinase Cation_efflux PF01545.21 CBK24027.2 - 4.9e-45 153.7 2.2 6e-45 153.4 2.2 1.1 1 0 0 1 1 1 1 Cation efflux family DUF772 PF05598.11 CBK24029.2 - 0.084 12.9 0.0 0.27 11.3 0.0 1.9 1 0 0 1 1 1 0 Transposase domain (DUF772) tRNA-synt_1g PF09334.11 CBK24030.2 - 6.6e-61 206.2 3.4 4.1e-59 200.3 3.4 2.6 1 1 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 CBK24030.2 - 2.2e-17 62.6 0.3 5.6e-13 48.0 0.3 2.9 2 1 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1e PF01406.19 CBK24030.2 - 3.7e-05 23.2 0.0 0.034 13.5 0.0 2.1 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain He_PIG PF05345.12 CBK24031.2 - 2.5e-19 69.2 21.6 2e-07 31.1 2.8 4.2 3 2 0 3 3 3 3 Putative Ig domain HRM PF02793.22 CBK24031.2 - 4.1e-06 27.0 18.5 0.00071 19.8 0.5 3.5 3 0 0 3 3 3 2 Hormone receptor domain DUF4834 PF16118.5 CBK24031.2 - 1.1e-05 26.3 2.4 1.1e-05 26.3 2.4 2.4 1 1 1 2 2 1 1 Domain of unknown function (DUF4834) DUF11 PF01345.18 CBK24031.2 - 2.6e-05 24.4 0.0 0.81 10.0 0.0 3.9 3 1 0 3 3 3 2 Domain of unknown function DUF11 SpoIIIAH PF12685.7 CBK24031.2 - 0.0019 18.1 4.5 0.0019 18.1 4.5 1.6 2 0 0 2 2 1 1 SpoIIIAH-like protein DUF4083 PF13314.6 CBK24031.2 - 0.0039 17.1 2.0 0.0083 16.1 2.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4083) Ninjurin PF04923.12 CBK24031.2 - 0.0047 16.8 1.9 0.011 15.6 1.9 1.6 1 0 0 1 1 1 1 Ninjurin MAP17 PF15807.5 CBK24031.2 - 0.0054 17.0 6.7 0.0054 17.0 6.7 2.3 1 1 1 2 2 2 1 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 Cytomega_TRL10 PF06084.11 CBK24031.2 - 0.009 16.0 0.1 0.02 14.9 0.1 1.7 1 0 0 1 1 1 1 Cytomegalovirus TRL10 protein SID-1_RNA_chan PF13965.6 CBK24031.2 - 0.019 13.4 4.5 0.03 12.8 4.5 1.2 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Neur_chan_memb PF02932.16 CBK24031.2 - 0.029 14.4 3.1 0.064 13.3 3.1 1.5 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region O-antigen_lig PF13425.6 CBK24031.2 - 0.031 13.1 1.1 0.053 12.3 1.1 1.2 1 0 0 1 1 1 0 O-antigen ligase like membrane protein DUF2615 PF11027.8 CBK24031.2 - 0.049 13.8 0.0 0.049 13.8 0.0 2.5 2 1 0 2 2 1 0 Protein of unknown function (DUF2615) V_ATPase_I PF01496.19 CBK24031.2 - 0.06 11.3 10.2 0.15 9.9 10.2 1.7 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family Serinc PF03348.15 CBK24031.2 - 0.087 11.7 3.3 0.16 10.9 3.3 1.4 1 0 0 1 1 1 0 Serine incorporator (Serinc) FeoB_associated PF12669.7 CBK24031.2 - 0.098 13.1 0.7 0.29 11.6 0.7 1.8 1 0 0 1 1 1 0 FeoB-associated Cys-rich membrane protein Zip PF02535.22 CBK24031.2 - 0.39 9.9 6.4 0.75 8.9 6.4 1.5 1 0 0 1 1 1 0 ZIP Zinc transporter Hid1 PF12722.7 CBK24031.2 - 0.99 7.5 9.7 1.3 7.1 9.7 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF3682 PF12446.8 CBK24031.2 - 5.4 7.5 24.6 0.1 13.1 12.5 2.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3682) Glycophorin_A PF01102.18 CBK24031.2 - 7.1 6.9 7.3 0.46 10.7 0.5 2.5 2 0 0 2 2 2 0 Glycophorin A SAPS PF04499.15 CBK24031.2 - 7.3 5.3 13.9 10 4.7 13.9 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein SLC12 PF03522.15 CBK24031.2 - 8.6 5.3 12.8 12 4.8 12.8 1.2 1 0 0 1 1 1 0 Solute carrier family 12 AFG1_ATPase PF03969.16 CBK24032.2 - 3.3e-77 259.8 0.1 2.7e-76 256.8 0.0 1.9 2 0 0 2 2 2 1 AFG1-like ATPase AAA_16 PF13191.6 CBK24032.2 - 0.00095 19.6 0.0 0.0024 18.3 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain Bac_DnaA PF00308.18 CBK24032.2 - 0.12 12.2 3.7 2.2 8.0 0.5 3.0 2 1 0 2 2 2 0 Bacterial dnaA protein AAA_22 PF13401.6 CBK24032.2 - 0.13 12.5 0.1 0.58 10.4 0.1 2.1 1 1 0 1 1 1 0 AAA domain UBD PF16455.5 CBK24033.2 - 1.7e-16 60.3 0.0 3.1e-16 59.5 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-binding domain Bet_v_1 PF00407.19 CBK24033.2 - 0.096 12.6 1.7 0.15 11.9 0.1 2.2 3 0 0 3 3 3 0 Pathogenesis-related protein Bet v I family Mustang PF15682.5 CBK24033.2 - 0.13 12.4 0.1 0.29 11.3 0.1 1.5 1 0 0 1 1 1 0 Musculoskeletal, temporally activated-embryonic nuclear protein 1 Peptidase_C12 PF01088.21 CBK24035.2 - 3.3e-20 72.8 0.0 3.5e-20 72.6 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 DUF3584 PF12128.8 CBK24036.2 - 0.023 12.2 10.7 0.028 12.0 10.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Galactosyl_T PF01762.21 CBK24037.2 - 1.5e-25 90.1 0.1 2.1e-25 89.7 0.1 1.1 1 0 0 1 1 1 1 Galactosyltransferase Fringe PF02434.16 CBK24037.2 - 3e-05 23.6 0.2 3.6e-05 23.3 0.2 1.1 1 0 0 1 1 1 1 Fringe-like Pam16 PF03656.13 CBK24038.2 - 2.2e-18 66.5 1.5 6.2e-18 65.0 0.8 2.2 1 1 1 2 2 2 1 Pam16 eIF3_p135 PF12807.7 CBK24039.2 - 1.7e-15 57.5 0.2 2.6e-15 56.9 0.2 1.2 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit 135 6PGD PF00393.19 CBK24040.2 - 8.5e-49 166.5 0.0 1.3e-48 165.8 0.0 1.3 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain DEAD PF00270.29 CBK24040.2 - 1.2e-35 122.8 0.1 2.2e-35 122.0 0.1 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CBK24040.2 - 4.8e-22 78.4 0.1 2.1e-21 76.3 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain NAD_binding_2 PF03446.15 CBK24040.2 - 8.7e-18 65.0 0.0 1.8e-17 64.0 0.0 1.6 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase CMS1 PF14617.6 CBK24040.2 - 0.01 15.2 0.0 0.02 14.3 0.0 1.3 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit Ribosomal_L29e PF01779.17 CBK24041.2 - 2.4e-20 72.5 9.2 2.4e-20 72.5 9.2 1.6 2 0 0 2 2 2 1 Ribosomal L29e protein family IRK_C PF17655.1 CBK24042.2 - 2.2e-11 43.7 0.0 2.8e-11 43.3 0.0 1.1 1 0 0 1 1 1 1 Inward rectifier potassium channel C-terminal domain Lactamase_B PF00753.27 CBK24044.2 - 7e-13 49.0 0.3 1.3e-12 48.1 0.3 1.4 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Bystin PF05291.11 CBK24045.2 - 7.9e-126 419.3 5.4 1.1e-125 418.7 5.4 1.2 1 0 0 1 1 1 1 Bystin Na_trans_assoc PF06512.13 CBK24045.2 - 0.56 10.5 12.6 0.086 13.1 8.9 1.5 2 0 0 2 2 2 0 Sodium ion transport-associated zf-Tim10_DDP PF02953.15 CBK24046.2 - 1.6e-11 43.7 1.2 2.3e-11 43.2 1.2 1.2 1 0 0 1 1 1 1 Tim10/DDP family zinc finger UPF0020 PF01170.18 CBK24047.2 - 3.1e-07 30.3 0.0 5e-06 26.3 0.0 2.4 2 1 0 2 2 2 1 Putative RNA methylase family UPF0020 N6_N4_Mtase PF01555.18 CBK24047.2 - 1.8e-06 27.8 0.0 4.9e-06 26.4 0.0 1.7 2 0 0 2 2 2 1 DNA methylase Cons_hypoth95 PF03602.15 CBK24047.2 - 0.0061 16.2 0.0 0.015 14.9 0.0 1.6 2 0 0 2 2 2 1 Conserved hypothetical protein 95 Glyco_transf_49 PF13896.6 CBK24048.2 - 4.9e-11 42.6 0.0 3.4e-05 23.4 0.0 2.2 1 1 1 2 2 2 2 Glycosyl-transferase for dystroglycan R3H PF01424.22 CBK24048.2 - 0.081 12.9 0.3 0.15 12.1 0.3 1.4 1 0 0 1 1 1 0 R3H domain TB2_DP1_HVA22 PF03134.19 CBK24049.2 - 0.034 14.1 4.6 0.042 13.8 2.2 2.4 1 1 1 2 2 2 0 TB2/DP1, HVA22 family Mito_carr PF00153.27 CBK24050.2 - 8.5e-60 198.7 2.7 4.2e-21 74.7 0.3 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Annexin_like PF18411.1 CBK24050.2 - 0.11 12.8 0.1 0.24 11.7 0.1 1.5 1 0 0 1 1 1 0 Annexin-like domain Thioredoxin_7 PF13899.6 CBK24051.2 - 2.6e-10 40.3 0.0 3.8e-10 39.8 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.6 CBK24051.2 - 0.067 13.7 0.0 0.11 13.0 0.0 1.5 1 1 0 1 1 1 0 Thioredoxin-like domain Thioredoxin_9 PF14595.6 CBK24051.2 - 0.12 12.2 0.0 0.2 11.4 0.0 1.4 2 0 0 2 2 2 0 Thioredoxin Ribosomal_L19e PF01280.20 CBK24052.2 - 4.9e-57 192.0 11.9 6.5e-57 191.6 11.9 1.1 1 0 0 1 1 1 1 Ribosomal protein L19e Aminotran_1_2 PF00155.21 CBK24053.2 - 1.2e-58 199.0 0.0 1.5e-58 198.7 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II HATPase_c_5 PF14501.6 CBK24053.2 - 0.0082 16.0 0.0 0.016 15.1 0.0 1.5 1 0 0 1 1 1 1 GHKL domain Romo1 PF10247.9 CBK24053.2 - 0.023 15.1 0.2 0.051 13.9 0.2 1.5 1 0 0 1 1 1 0 Reactive mitochondrial oxygen species modulator 1 Cwf_Cwc_15 PF04889.12 CBK24054.2 - 0.0019 18.0 0.3 0.0031 17.3 0.3 1.2 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein zf-C2H2_12 PF18658.1 CBK24054.2 - 0.018 14.6 0.3 0.018 14.6 0.3 3.0 2 0 0 2 2 2 0 Zinc-finger C2H2-type F-box PF00646.33 CBK24054.2 - 0.041 13.8 3.2 2.7 8.0 0.0 3.5 3 0 0 3 3 3 0 F-box domain Ufd2P_core PF10408.9 CBK24055.2 - 1.7e-18 66.6 1.0 2.2e-18 66.3 1.0 1.1 1 0 0 1 1 1 1 Ubiquitin elongating factor core U-box PF04564.15 CBK24055.2 - 1.2e-15 57.4 0.3 2.5e-15 56.4 0.3 1.6 1 0 0 1 1 1 1 U-box domain HAND PF09110.11 CBK24055.2 - 0.0011 19.7 0.7 0.0023 18.7 0.7 1.6 1 0 0 1 1 1 1 HAND DUF3696 PF12476.8 CBK24055.2 - 0.044 14.2 1.5 0.096 13.1 1.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3696) DUF3813 PF12758.7 CBK24055.2 - 0.055 13.8 1.2 0.14 12.5 1.2 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3813) Ufd2P_core PF10408.9 CBK24056.2 - 1.6e-19 70.0 6.7 3.2e-16 59.1 3.3 2.0 2 0 0 2 2 2 2 Ubiquitin elongating factor core Aa_trans PF01490.18 CBK24057.2 - 1e-47 162.8 28.8 1.2e-47 162.5 28.8 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Dyp_perox PF04261.12 CBK24058.2 - 2.8e-48 164.6 0.0 3e-48 164.5 0.0 1.1 1 0 0 1 1 1 1 Dyp-type peroxidase family Usp PF00582.26 CBK24059.2 - 1.6e-24 87.0 0.0 5e-24 85.4 0.0 1.8 1 0 0 1 1 1 1 Universal stress protein family PH PF00169.29 CBK24060.2 - 1.1e-10 42.0 0.0 2.7e-10 40.7 0.0 1.6 2 0 0 2 2 2 1 PH domain Pkinase PF00069.25 CBK24060.2 - 0.00036 20.0 0.0 0.00075 18.9 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain PH_8 PF15409.6 CBK24060.2 - 0.0042 17.3 0.0 0.0089 16.3 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain PH_11 PF15413.6 CBK24060.2 - 0.011 16.1 0.7 0.076 13.4 0.7 2.3 2 1 0 2 2 2 0 Pleckstrin homology domain Pkinase_Tyr PF07714.17 CBK24060.2 - 0.045 13.0 0.0 0.19 11.0 0.0 1.9 2 0 0 2 2 2 0 Protein tyrosine kinase PH_9 PF15410.6 CBK24060.2 - 0.12 12.7 0.2 0.58 10.5 0.1 2.1 1 1 0 1 1 1 0 Pleckstrin homology domain TFIID_30kDa PF03540.13 CBK24061.2 - 1.8e-16 59.8 0.1 3.1e-16 59.1 0.1 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID 23-30kDa subunit TAF4 PF05236.14 CBK24061.2 - 0.0024 17.7 0.2 0.0024 17.7 0.2 1.2 1 0 0 1 1 1 1 Transcription initiation factor TFIID component TAF4 family CSTF2_hinge PF14327.6 CBK24061.2 - 0.037 14.5 0.3 0.12 12.8 0.1 1.8 2 0 0 2 2 2 0 Hinge domain of cleavage stimulation factor subunit 2 TAFII28 PF04719.14 CBK24061.2 - 0.051 13.7 0.0 0.08 13.0 0.0 1.5 1 1 0 1 1 1 0 hTAFII28-like protein conserved region Bromo_TP PF07524.13 CBK24061.2 - 0.053 13.5 0.0 0.35 10.9 0.0 2.0 1 1 0 1 1 1 0 Bromodomain associated GTP_EFTU PF00009.27 CBK24062.2 - 1.9e-27 96.1 0.2 2.9e-27 95.5 0.2 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 CBK24062.2 - 9.8e-07 28.9 0.1 2e-06 27.8 0.1 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.25 CBK24062.2 - 2.8e-06 27.6 0.2 1.4e-05 25.4 0.0 2.4 3 0 0 3 3 3 1 Elongation factor Tu domain 2 RIBIOP_C PF04950.12 CBK24062.2 - 2.1e-05 24.1 0.5 0.00026 20.5 0.1 2.4 3 0 0 3 3 3 1 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal SRPRB PF09439.10 CBK24062.2 - 0.0011 18.4 0.8 0.01 15.3 0.8 2.2 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit cobW PF02492.19 CBK24062.2 - 0.0012 18.5 0.3 0.038 13.6 0.1 2.2 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain ATP_bind_1 PF03029.17 CBK24062.2 - 0.0063 16.3 0.4 2.3 7.9 0.0 3.1 2 1 0 2 2 2 1 Conserved hypothetical ATP binding protein RsgA_GTPase PF03193.16 CBK24062.2 - 0.023 14.6 1.2 0.095 12.6 0.1 2.2 2 0 0 2 2 2 0 RsgA GTPase HMG_box PF00505.19 CBK24063.2 - 5.3e-10 39.6 3.0 1e-09 38.6 3.0 1.5 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 CBK24063.2 - 3e-07 30.9 3.7 3e-07 30.9 3.7 2.0 2 0 0 2 2 2 1 HMG-box domain zf-C2H2 PF00096.26 CBK24063.2 - 4.9e-06 26.7 5.8 0.025 15.0 0.8 3.2 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CBK24063.2 - 0.0048 17.6 9.3 0.62 11.1 0.7 3.3 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_8 PF15909.5 CBK24063.2 - 0.012 15.9 1.3 0.039 14.2 0.3 2.1 2 0 0 2 2 2 0 C2H2-type zinc ribbon Androgen_recep PF02166.16 CBK24063.2 - 0.062 12.1 0.2 0.09 11.6 0.2 1.2 1 0 0 1 1 1 0 Androgen receptor LAG1-DNAbind PF09271.11 CBK24063.2 - 0.29 11.7 2.5 0.64 10.6 0.1 2.1 2 0 0 2 2 2 0 LAG1, DNA binding zf-H2C2_2 PF13465.6 CBK24063.2 - 0.82 10.2 10.1 0.4 11.2 0.8 3.3 3 0 0 3 3 3 0 Zinc-finger double domain UNC-93 PF05978.16 CBK24064.2 - 2.5e-15 56.5 10.4 2.5e-15 56.5 10.4 2.9 2 1 0 2 2 2 1 Ion channel regulatory protein UNC-93 Orai-1 PF07856.12 CBK24064.2 - 0.00037 20.2 0.9 0.00071 19.3 0.1 1.9 2 1 0 2 2 2 1 Mediator of CRAC channel activity Trp_oprn_chp PF09534.10 CBK24064.2 - 0.12 12.1 4.4 0.51 10.1 4.3 2.0 1 1 1 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) DUF1751 PF08551.10 CBK24064.2 - 0.28 11.8 11.0 0.13 12.8 1.5 3.6 3 0 0 3 3 3 0 Eukaryotic integral membrane protein (DUF1751) PTEN_C2 PF10409.9 CBK24065.2 - 2.8e-05 23.9 0.0 5.2e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 C2 domain of PTEN tumour-suppressor protein DSPc PF00782.20 CBK24065.2 - 5.5e-05 23.0 0.1 0.0001 22.1 0.1 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain CDKN3 PF05706.12 CBK24065.2 - 0.00018 21.3 0.1 0.00029 20.5 0.1 1.3 1 0 0 1 1 1 1 Cyclin-dependent kinase inhibitor 3 (CDKN3) Y_phosphatase3 PF13350.6 CBK24065.2 - 0.0012 18.8 0.0 0.0024 17.9 0.0 1.4 1 0 0 1 1 1 1 Tyrosine phosphatase family PTPlike_phytase PF14566.6 CBK24065.2 - 0.013 15.6 0.0 0.026 14.6 0.0 1.4 1 0 0 1 1 1 0 Inositol hexakisphosphate Y_phosphatase2 PF03162.13 CBK24065.2 - 0.028 14.0 0.0 0.077 12.6 0.0 1.7 2 0 0 2 2 2 0 Tyrosine phosphatase family Y_phosphatase PF00102.27 CBK24065.2 - 0.089 12.3 0.2 0.17 11.4 0.2 1.5 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Prok-E2_D PF14460.6 CBK24065.2 - 0.14 11.8 0.1 0.32 10.7 0.1 1.5 1 0 0 1 1 1 0 Prokaryotic E2 family D Mpv17_PMP22 PF04117.12 CBK24066.2 - 4.3e-14 52.5 0.2 7e-14 51.8 0.2 1.4 1 0 0 1 1 1 1 Mpv17 / PMP22 family MOZART1 PF12554.8 CBK24067.2 - 4.1e-17 61.7 0.0 5.2e-17 61.4 0.0 1.1 1 0 0 1 1 1 1 Mitotic-spindle organizing gamma-tubulin ring associated MOZART2 PF12926.7 CBK24067.2 - 0.11 12.1 0.0 0.13 11.9 0.0 1.0 1 0 0 1 1 1 0 Mitotic-spindle organizing gamma-tubulin ring associated TPR_MLP1_2 PF07926.12 CBK24068.2 - 0.0028 17.7 13.1 0.0028 17.7 13.1 5.9 1 1 4 5 5 5 3 TPR/MLP1/MLP2-like protein DUF812 PF05667.11 CBK24068.2 - 0.02 13.8 73.9 0.082 11.8 17.4 4.1 1 1 3 4 4 4 0 Protein of unknown function (DUF812) APG6_N PF17675.1 CBK24068.2 - 0.023 15.2 25.0 0.023 15.2 25.0 5.2 1 1 3 4 4 3 0 Apg6 coiled-coil region Spc7 PF08317.11 CBK24068.2 - 0.03 13.2 82.1 0.15 10.9 15.1 4.1 1 1 3 4 4 4 0 Spc7 kinetochore protein DUF3851 PF12962.7 CBK24068.2 - 0.19 12.1 2.7 0.47 10.7 2.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3851) ATG16 PF08614.11 CBK24068.2 - 0.55 10.4 87.3 1.5 9.0 7.8 4.5 1 1 3 4 4 4 0 Autophagy protein 16 (ATG16) DUF641 PF04859.12 CBK24068.2 - 1.9 8.9 56.1 0.23 11.8 1.9 5.4 2 1 3 5 5 5 0 Plant protein of unknown function (DUF641) DUF4686 PF15742.5 CBK24068.2 - 2.3 7.3 80.4 0.5 9.4 25.1 3.2 2 1 1 3 3 3 0 Domain of unknown function (DUF4686) Endotoxin_N PF03945.14 CBK24068.2 - 3.7 7.2 5.5 2.8 7.6 2.0 2.3 2 1 1 3 3 3 0 delta endotoxin, N-terminal domain HOOK PF05622.12 CBK24068.2 - 3.9 5.5 68.6 0.082 11.0 15.1 2.7 1 1 1 2 2 2 0 HOOK protein HMMR_N PF15905.5 CBK24068.2 - 5 6.5 75.5 0.035 13.6 23.4 3.3 1 1 2 3 3 3 0 Hyaluronan mediated motility receptor N-terminal PI_PP_I PF18363.1 CBK24068.2 - 5.3 7.3 7.0 1.3 9.2 1.4 2.9 2 1 1 3 3 3 0 Phosphoinositide phosphatase insertion domain Metal_resist PF13801.6 CBK24069.2 - 0.02 15.1 2.1 0.02 15.1 2.1 6.4 4 2 2 6 6 6 0 Heavy-metal resistance ATG27 PF09451.10 CBK24069.2 - 0.024 14.5 0.5 0.065 13.1 0.5 1.7 1 0 0 1 1 1 0 Autophagy-related protein 27 ATG16 PF08614.11 CBK24069.2 - 0.091 13.0 107.8 0.024 14.9 12.8 5.8 1 1 4 5 5 5 0 Autophagy protein 16 (ATG16) DUF1759 PF03564.15 CBK24069.2 - 8.7 6.3 25.7 0.13 12.2 0.9 4.7 3 2 0 4 4 4 0 Protein of unknown function (DUF1759) Sec5 PF15469.6 CBK24070.2 - 5.7e-17 62.2 1.8 5.7e-17 62.2 1.8 1.6 1 1 1 2 2 2 1 Exocyst complex component Sec5 Vps51 PF08700.11 CBK24070.2 - 6.5e-09 35.8 0.4 6.5e-09 35.8 0.4 2.6 3 0 0 3 3 3 1 Vps51/Vps67 Dor1 PF04124.12 CBK24070.2 - 2.4e-07 29.8 3.4 3.6e-07 29.2 1.9 1.7 1 1 1 2 2 2 1 Dor1-like family Vps54_N PF10475.9 CBK24070.2 - 3.4e-06 26.5 3.6 4e-06 26.3 2.1 1.6 1 1 1 2 2 2 1 Vacuolar-sorting protein 54, of GARP complex COG2 PF06148.11 CBK24070.2 - 0.00096 19.3 6.3 0.01 15.9 0.9 2.6 1 1 1 2 2 2 1 COG (conserved oligomeric Golgi) complex component, COG2 Vps53_N PF04100.12 CBK24070.2 - 0.038 13.0 1.1 0.059 12.3 1.1 1.2 1 0 0 1 1 1 0 Vps53-like, N-terminal Occludin_ELL PF07303.13 CBK24070.2 - 0.1 13.3 0.8 1.5 9.6 0.0 2.7 1 1 3 4 4 4 0 Occludin homology domain CENP-F_leu_zip PF10473.9 CBK24070.2 - 0.15 12.1 2.8 0.19 11.8 0.3 2.2 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Syntaxin-6_N PF09177.11 CBK24070.2 - 0.18 12.4 1.0 3.8 8.1 0.1 2.4 2 1 0 2 2 2 0 Syntaxin 6, N-terminal TRPM_tetra PF16519.5 CBK24070.2 - 0.19 11.8 2.3 6.9 6.9 0.2 2.7 2 0 0 2 2 2 0 Tetramerisation domain of TRPM COG5 PF10392.9 CBK24070.2 - 0.21 11.8 3.9 1.7 8.8 0.4 2.7 2 1 0 2 2 2 0 Golgi transport complex subunit 5 Laminin_II PF06009.12 CBK24070.2 - 0.59 10.2 3.3 1.2 9.2 0.3 2.5 2 1 1 3 3 3 0 Laminin Domain II Noelin-1 PF12308.8 CBK24070.2 - 0.63 10.0 4.3 3.9 7.5 0.5 2.5 2 0 0 2 2 2 0 Neurogenesis glycoprotein BBP1_C PF15272.6 CBK24070.2 - 0.9 9.3 5.1 0.79 9.5 0.1 2.7 3 0 0 3 3 3 0 Spindle pole body component BBP1, C-terminal FlaC_arch PF05377.11 CBK24070.2 - 9.5 6.7 6.6 1.1 9.7 0.3 2.7 3 1 0 3 3 2 0 Flagella accessory protein C (FlaC) Sel1 PF08238.12 CBK24072.2 - 5.2e-26 90.5 20.2 6.4e-08 33.0 0.0 9.6 10 0 0 10 10 10 8 Sel1 repeat tRNA-synt_1c PF00749.21 CBK24073.2 - 5.3e-107 357.3 0.0 7.5e-107 356.8 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.18 CBK24073.2 - 2.6e-39 134.9 0.0 4.7e-39 134.0 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain tRNA_synt_1c_R1 PF04558.15 CBK24073.2 - 9.1e-24 84.3 0.3 4e-23 82.2 0.1 2.1 2 0 0 2 2 2 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 tRNA_synt_1c_R2 PF04557.15 CBK24073.2 - 3.4e-06 27.9 5.7 8.7e-06 26.6 5.7 1.7 1 0 0 1 1 1 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 2 MFS_1 PF07690.16 CBK24074.2 - 2.5e-13 49.7 4.4 3e-13 49.4 4.4 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF2208 PF09973.9 CBK24074.2 - 0.075 12.6 0.0 7.3 6.1 0.0 2.2 2 0 0 2 2 2 0 Predicted membrane protein (DUF2208) Ninjurin PF04923.12 CBK24074.2 - 0.11 12.5 0.0 0.21 11.5 0.0 1.5 1 0 0 1 1 1 0 Ninjurin DUF2304 PF10066.9 CBK24074.2 - 1.2 9.4 0.0 1.2 9.4 0.0 2.9 3 1 1 4 4 4 0 Uncharacterized conserved protein (DUF2304) DUF4574 PF15141.6 CBK24074.2 - 2.4 8.1 4.3 3.7 7.5 0.0 2.8 3 0 0 3 3 3 0 Ubiquinol-cytochrome-c reductase complex assembly factor 3 MFS_1 PF07690.16 CBK24075.2 - 3e-05 23.1 2.4 3.1e-05 23.1 2.4 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.6 CBK24075.2 - 0.01 14.4 6.7 0.012 14.2 6.7 1.1 1 0 0 1 1 1 0 MFS/sugar transport protein S_2TMBeta PF18153.1 CBK24075.2 - 0.053 13.3 0.0 0.065 13.0 0.0 1.1 1 0 0 1 1 1 0 SMODS-associating 2TM, beta-strand rich effector domain Phage_holin_3_6 PF07332.11 CBK24075.2 - 0.1 12.6 0.3 0.1 12.6 0.3 1.8 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III FAM176 PF14851.6 CBK24075.2 - 0.11 12.1 0.0 0.15 11.7 0.0 1.2 1 0 0 1 1 1 0 FAM176 family DUF21 PF01595.20 CBK24075.2 - 0.84 9.3 5.8 1.3 8.7 5.8 1.2 1 0 0 1 1 1 0 Cyclin M transmembrane N-terminal domain Bromodomain PF00439.25 CBK24076.2 - 8.9e-06 25.7 0.0 1.1e-05 25.4 0.0 1.1 1 0 0 1 1 1 1 Bromodomain NIF PF03031.18 CBK24078.2 - 2.1e-10 40.6 0.0 3.4e-10 39.9 0.0 1.3 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Protamine_P2 PF00841.19 CBK24078.2 - 0.047 14.2 0.3 0.047 14.2 0.3 2.4 3 0 0 3 3 3 0 Sperm histone P2 Type2_restr_D3 PF16902.5 CBK24078.2 - 0.19 11.7 1.7 1.5 8.8 0.0 2.7 3 0 0 3 3 3 0 Type-2 restriction enzyme D3 domain HEAT_EZ PF13513.6 CBK24079.2 - 1.1e-05 25.8 0.3 0.18 12.3 0.0 3.4 3 1 1 4 4 4 3 HEAT-like repeat HEAT PF02985.22 CBK24079.2 - 3.8e-05 23.6 1.7 0.015 15.5 0.0 4.1 4 1 0 4 4 4 1 HEAT repeat HEAT_2 PF13646.6 CBK24079.2 - 0.0016 18.8 0.0 0.0065 16.8 0.0 1.9 2 0 0 2 2 2 1 HEAT repeats CLASP_N PF12348.8 CBK24079.2 - 0.015 14.9 0.0 0.31 10.6 0.0 2.3 1 1 1 2 2 2 0 CLASP N terminal Adaptin_N PF01602.20 CBK24079.2 - 0.02 13.5 0.0 0.024 13.2 0.0 1.3 1 0 0 1 1 1 0 Adaptin N terminal region Cnd1 PF12717.7 CBK24079.2 - 0.049 13.7 0.0 0.093 12.8 0.0 1.5 1 0 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 CBK24080.2 - 5.3e-06 26.2 0.4 0.13 12.5 0.0 5.4 5 0 0 5 5 5 1 HEAT repeat IBN_N PF03810.19 CBK24080.2 - 0.0011 18.9 0.0 0.0082 16.0 0.0 2.4 2 0 0 2 2 2 1 Importin-beta N-terminal domain Arm PF00514.23 CBK24080.2 - 0.0064 16.5 3.5 0.062 13.4 0.1 3.9 5 0 0 5 5 5 1 Armadillo/beta-catenin-like repeat Cnd1 PF12717.7 CBK24080.2 - 0.008 16.2 0.2 0.042 13.9 0.1 2.1 1 1 0 1 1 1 1 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 CBK24080.2 - 0.0087 14.7 2.0 1.6 7.2 0.1 2.2 1 1 1 2 2 2 2 Adaptin N terminal region HEAT_2 PF13646.6 CBK24080.2 - 0.027 14.9 0.3 3 8.3 0.0 3.5 2 1 1 3 3 3 0 HEAT repeats Katanin_con80 PF13925.6 CBK24080.2 - 0.031 14.3 0.0 0.081 13.0 0.0 1.6 1 0 0 1 1 1 0 con80 domain of Katanin Vac14_Fab1_bd PF12755.7 CBK24080.2 - 0.081 13.5 0.2 3.4 8.3 0.0 3.2 2 1 2 4 4 4 0 Vacuolar 14 Fab1-binding region U3snoRNP10 PF12397.8 CBK24080.2 - 0.11 12.8 1.3 1.2 9.5 0.0 2.8 3 0 0 3 3 3 0 U3 small nucleolar RNA-associated protein 10 HEAT_EZ PF13513.6 CBK24080.2 - 0.16 12.5 5.0 88 3.8 0.1 4.7 4 1 1 5 5 5 0 HEAT-like repeat Use1 PF09753.9 CBK24081.2 - 8.5e-08 32.2 18.2 1.9e-05 24.5 18.2 2.1 1 1 0 1 1 1 1 Membrane fusion protein Use1 Gag_p30 PF02093.16 CBK24081.2 - 0.0023 17.5 1.0 0.0073 15.8 0.2 2.1 2 1 0 2 2 2 1 Gag P30 core shell protein DUF1664 PF07889.12 CBK24081.2 - 0.12 12.4 6.5 1.5 8.8 0.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) BAG PF02179.16 CBK24081.2 - 0.12 12.8 4.8 0.13 12.8 0.7 2.9 2 1 1 3 3 3 0 BAG domain DASH_Dam1 PF08653.10 CBK24081.2 - 0.14 12.0 3.2 12 5.8 0.0 3.8 4 0 0 4 4 4 0 DASH complex subunit Dam1 AKNA PF12443.8 CBK24081.2 - 0.21 12.3 9.8 2.3 8.9 3.2 3.1 2 1 1 3 3 3 0 AT-hook-containing transcription factor DUF2357 PF09823.9 CBK24081.2 - 0.21 10.8 6.3 0.62 9.3 0.8 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF2357) Occludin_ELL PF07303.13 CBK24081.2 - 0.48 11.2 7.0 0.19 12.5 0.5 2.7 2 1 1 3 3 3 0 Occludin homology domain BLOC1_2 PF10046.9 CBK24081.2 - 0.83 10.0 11.9 2.1 8.7 0.1 3.2 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 MtrG PF04210.13 CBK24081.2 - 0.87 9.5 2.7 1.5 8.8 0.1 2.7 3 0 0 3 3 3 0 Tetrahydromethanopterin S-methyltransferase, subunit G Cauli_AT PF03233.13 CBK24081.2 - 3.2 7.6 13.5 5.2 7.0 4.3 2.2 2 0 0 2 2 2 0 Aphid transmission protein LMBR1 PF04791.16 CBK24081.2 - 3.5 6.4 11.1 19 4.0 11.2 1.8 1 1 0 1 1 1 0 LMBR1-like membrane protein Ribosomal_L27A PF00828.19 CBK24082.2 - 1.6e-22 80.5 0.0 2.4e-22 80.0 0.0 1.3 1 0 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A Ribosom_S12_S23 PF00164.25 CBK24083.2 - 4.2e-48 161.7 1.9 5.1e-48 161.4 1.9 1.2 1 0 0 1 1 1 1 Ribosomal protein S12/S23 Nucleotid_trans PF03407.16 CBK24084.2 - 6.6e-23 81.8 0.1 9.8e-23 81.2 0.1 1.3 1 0 0 1 1 1 1 Nucleotide-diphospho-sugar transferase DUF3880 PF12996.7 CBK24084.2 - 0.023 14.8 0.1 0.059 13.5 0.1 1.8 1 0 0 1 1 1 0 DUF based on E. rectale Gene description (DUF3880) Ribonuc_L-PSP PF01042.21 CBK24085.2 - 4.2e-42 143.0 0.1 5.1e-42 142.7 0.1 1.1 1 0 0 1 1 1 1 Endoribonuclease L-PSP YjgF_endoribonc PF14588.6 CBK24085.2 - 0.024 14.8 0.0 0.047 13.8 0.0 1.5 1 1 0 1 1 1 0 YjgF/chorismate_mutase-like, putative endoribonuclease PPR_2 PF13041.6 CBK24086.2 - 2.9e-22 78.6 0.1 3.6e-11 43.1 0.0 4.7 2 2 2 4 4 4 2 PPR repeat family PPR_3 PF13812.6 CBK24086.2 - 2.6e-16 59.5 0.0 1.7e-08 34.4 0.0 3.9 3 0 0 3 3 3 3 Pentatricopeptide repeat domain PPR PF01535.20 CBK24086.2 - 1.7e-15 56.1 1.9 7.4e-07 29.0 0.0 5.5 5 0 0 5 5 5 2 PPR repeat PPR_1 PF12854.7 CBK24086.2 - 3e-13 49.2 0.0 1.7e-07 30.8 0.0 3.7 3 0 0 3 3 3 3 PPR repeat PPR_long PF17177.4 CBK24086.2 - 1.2e-08 34.6 0.0 1.5e-06 27.7 0.0 2.3 2 0 0 2 2 2 2 Pentacotripeptide-repeat region of PRORP TPR_19 PF14559.6 CBK24086.2 - 0.0076 16.7 0.0 0.086 13.4 0.0 2.6 3 0 0 3 3 3 1 Tetratricopeptide repeat IlvC PF01450.19 CBK24086.2 - 0.016 15.5 0.0 0.048 13.9 0.0 1.8 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, catalytic domain Ank_3 PF13606.6 CBK24087.2 - 1.9e-15 55.4 0.7 0.0039 17.6 0.1 4.9 5 0 0 5 5 5 3 Ankyrin repeat Ank_2 PF12796.7 CBK24087.2 - 6.1e-15 55.6 0.3 8.5e-09 35.9 0.0 2.8 1 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 CBK24087.2 - 1.7e-14 53.7 1.2 1.2e-05 25.4 0.1 3.6 2 2 1 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 CBK24087.2 - 2.7e-14 52.9 1.2 0.002 18.5 0.0 3.7 3 0 0 3 3 3 3 Ankyrin repeat Ank_4 PF13637.6 CBK24087.2 - 1.6e-12 47.7 0.7 1.4e-05 25.5 0.0 4.1 4 1 1 5 5 5 3 Ankyrin repeats (many copies) HTH_18 PF12833.7 CBK24087.2 - 0.031 14.5 0.1 0.21 11.9 0.0 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain CsgA PF17334.2 CBK24087.2 - 0.17 12.7 0.0 0.3 11.8 0.0 1.4 1 0 0 1 1 1 0 Minor curli fiber component A UQ_con PF00179.26 CBK24088.2 - 4.6e-30 104.1 0.1 5.7e-30 103.8 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 CBK24088.2 - 0.00013 22.3 0.0 0.00022 21.5 0.0 1.4 1 0 0 1 1 1 1 RWD domain Prok-E2_B PF14461.6 CBK24088.2 - 0.0053 16.4 0.0 0.0085 15.8 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic E2 family B Kinesin PF00225.23 CBK24090.2 - 4.6e-68 229.6 0.3 4.6e-68 229.6 0.3 3.8 4 1 1 5 5 5 1 Kinesin motor domain Cation_efflux PF01545.21 CBK24091.2 - 5.4e-14 52.4 0.1 7e-14 52.0 0.1 1.1 1 0 0 1 1 1 1 Cation efflux family XFP_N PF09364.10 CBK24091.2 - 0.1 11.4 0.0 0.14 10.9 0.0 1.2 1 0 0 1 1 1 0 XFP N-terminal domain Use1 PF09753.9 CBK24092.2 - 3.3e-06 27.0 5.3 4.5e-06 26.6 5.3 1.2 1 0 0 1 1 1 1 Membrane fusion protein Use1 Fib_alpha PF08702.10 CBK24092.2 - 0.0094 16.1 6.8 0.015 15.5 6.8 1.4 1 0 0 1 1 1 1 Fibrinogen alpha/beta chain family Syntaxin-6_N PF09177.11 CBK24092.2 - 0.011 16.2 12.9 0.04 14.5 0.3 3.1 1 1 2 3 3 3 0 Syntaxin 6, N-terminal Polyhedrin PF00738.18 CBK24092.2 - 0.031 13.6 0.8 0.037 13.4 0.8 1.2 1 0 0 1 1 1 0 Polyhedrin SNARE PF05739.19 CBK24092.2 - 0.059 13.4 11.1 1.1 9.3 8.5 3.1 2 1 0 2 2 2 0 SNARE domain DUF2861 PF11060.8 CBK24092.2 - 0.083 12.5 2.0 0.12 12.0 1.9 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2861) DUF812 PF05667.11 CBK24092.2 - 0.1 11.5 10.3 0.12 11.2 10.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) DUF445 PF04286.12 CBK24092.2 - 0.22 11.3 6.6 0.29 10.9 6.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF445) Baculo_p24 PF05073.12 CBK24092.2 - 0.24 11.2 2.5 0.33 10.7 2.5 1.3 1 0 0 1 1 1 0 Baculovirus P24 capsid protein DUF745 PF05335.13 CBK24092.2 - 0.28 10.9 3.3 0.51 10.0 3.3 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF745) DUF4239 PF14023.6 CBK24092.2 - 0.45 10.2 6.5 0.12 12.1 1.5 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF4239) Atg14 PF10186.9 CBK24092.2 - 0.64 9.0 8.0 0.77 8.8 8.0 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 UPF0242 PF06785.11 CBK24092.2 - 1.6 8.8 11.6 0.28 11.3 5.2 2.1 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Ly49 PF08391.10 CBK24092.2 - 1.8 9.0 4.6 3.3 8.1 0.3 2.4 1 1 1 2 2 2 0 Ly49-like protein, N-terminal region FHIPEP PF00771.20 CBK24092.2 - 1.8 6.9 6.7 2.3 6.6 6.7 1.1 1 0 0 1 1 1 0 FHIPEP family CorA PF01544.18 CBK24092.2 - 1.8 7.8 8.3 2.6 7.3 8.3 1.3 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein FAM76 PF16046.5 CBK24092.2 - 2.4 7.4 6.2 3.1 7.1 6.2 1.1 1 0 0 1 1 1 0 FAM76 protein DUF4407 PF14362.6 CBK24092.2 - 2.5 7.4 8.1 5.7 6.2 8.1 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Spc7 PF08317.11 CBK24092.2 - 3.1 6.6 13.0 8.4 5.2 12.9 1.6 1 1 0 1 1 1 0 Spc7 kinetochore protein DUF883 PF05957.13 CBK24092.2 - 3.3 8.4 7.2 2.5 8.7 2.0 2.4 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF883) TMPIT PF07851.13 CBK24092.2 - 9.9 5.3 8.1 25 4.0 8.1 1.8 1 1 0 1 1 1 0 TMPIT-like protein NUC173 PF08161.12 CBK24093.2 - 4.1e-46 157.2 0.8 5.7e-45 153.5 0.1 2.8 3 0 0 3 3 3 1 NUC173 domain MMS19_N PF14500.6 CBK24093.2 - 0.1 12.1 2.7 0.48 10.0 0.2 2.8 3 0 0 3 3 3 0 Dos2-interacting transcription regulator of RNA-Pol-II GTP_EFTU PF00009.27 CBK24094.2 - 6.7e-50 169.3 0.0 1.4e-49 168.3 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_II PF14492.6 CBK24094.2 - 4.3e-23 81.2 0.1 1.3e-22 79.7 0.1 1.9 1 0 0 1 1 1 1 Elongation Factor G, domain II RF3_C PF16658.5 CBK24094.2 - 1.6e-09 37.7 0.8 4.2e-09 36.3 0.8 1.7 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain GTP_EFTU_D2 PF03144.25 CBK24094.2 - 3.3e-07 30.6 0.5 6.8e-07 29.6 0.5 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_IV PF03764.18 CBK24094.2 - 0.00011 22.0 0.0 0.0002 21.1 0.0 1.5 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.24 CBK24094.2 - 0.026 14.5 0.0 0.086 12.9 0.0 1.9 1 0 0 1 1 1 0 Elongation factor G C-terminus AIG1 PF04548.16 CBK24094.2 - 0.037 13.3 0.0 0.098 12.0 0.0 1.7 1 0 0 1 1 1 0 AIG1 family T2SSM_b PF10741.9 CBK24094.2 - 0.078 12.8 0.2 2.2 8.1 0.1 2.4 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein M subtype b MMR_HSR1 PF01926.23 CBK24094.2 - 0.11 12.6 0.0 0.35 10.9 0.0 1.9 1 0 0 1 1 1 0 50S ribosome-binding GTPase BET PF17035.5 CBK24094.2 - 1.7 8.9 8.1 2.6 8.3 0.9 3.0 3 0 0 3 3 3 0 Bromodomain extra-terminal - transcription regulation LRR_4 PF12799.7 CBK24095.2 - 0.0041 17.5 4.3 4.9 7.7 0.1 5.0 2 2 2 4 4 4 1 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CBK24095.2 - 0.024 14.4 5.9 5.3 6.9 0.1 4.2 5 0 0 5 5 5 0 Leucine rich repeat tRNA-synt_1 PF00133.22 CBK24096.2 - 3.8e-145 484.5 0.1 5.1e-145 484.1 0.1 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 CBK24096.2 - 4.2e-29 101.5 0.2 7.2e-29 100.7 0.2 1.4 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 CBK24096.2 - 5.3e-15 55.1 0.1 7.4e-08 31.5 0.0 3.6 3 0 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.6 CBK24096.2 - 0.00036 20.1 0.0 0.00085 18.9 0.0 1.6 1 0 0 1 1 1 1 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1e PF01406.19 CBK24096.2 - 0.014 14.7 0.0 0.35 10.2 0.0 2.3 2 0 0 2 2 2 0 tRNA synthetases class I (C) catalytic domain UCH PF00443.29 CBK24097.2 - 7.8e-16 58.3 0.7 9.3e-16 58.1 0.7 1.3 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 CBK24097.2 - 0.085 12.4 3.7 0.27 10.8 3.7 2.0 1 1 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase Humanin PF15040.6 CBK24097.2 - 0.092 12.2 0.0 0.46 10.0 0.0 2.0 2 0 0 2 2 2 0 Humanin family UCH PF00443.29 CBK24098.2 - 2e-24 86.5 0.5 2.5e-24 86.2 0.5 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Casein PF00363.18 CBK24098.2 - 0.008 16.5 0.2 0.031 14.6 0.2 2.0 1 0 0 1 1 1 1 Casein tRNA_anti_2 PF13742.6 CBK24098.2 - 0.016 15.4 1.8 0.049 13.8 0.2 2.3 2 0 0 2 2 2 0 OB-fold nucleic acid binding domain SusD_RagB PF07980.11 CBK24098.2 - 0.046 13.3 0.9 0.068 12.8 0.9 1.2 1 0 0 1 1 1 0 SusD family ECH_1 PF00378.20 CBK24099.2 - 1.7e-16 60.3 0.0 1.8e-16 60.2 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 CBK24099.2 - 5.7e-09 35.9 0.1 6.9e-09 35.6 0.1 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase CPSase_L_D2 PF02786.17 CBK24100.2 - 1.3e-53 181.7 0.0 3.3e-53 180.3 0.0 1.6 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 CBK24100.2 - 5.6e-41 139.5 0.0 1e-40 138.7 0.0 1.4 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Dala_Dala_lig_C PF07478.13 CBK24100.2 - 3.4e-07 30.0 0.0 9.3e-07 28.6 0.0 1.7 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 CBK24100.2 - 0.00087 18.9 0.0 0.0032 17.1 0.0 1.9 2 0 0 2 2 2 1 ATP-grasp domain GARS_N PF02844.15 CBK24100.2 - 0.069 13.9 0.1 5.4 7.9 0.0 3.2 3 1 0 3 3 3 0 Phosphoribosylglycinamide synthetase, N domain VirE PF05272.11 CBK24100.2 - 0.11 12.2 0.0 0.22 11.2 0.0 1.4 1 0 0 1 1 1 0 Virulence-associated protein E ATP-grasp_5 PF13549.6 CBK24100.2 - 0.16 11.4 0.0 0.32 10.4 0.0 1.4 1 0 0 1 1 1 0 ATP-grasp domain Biotin_lipoyl PF00364.22 CBK24101.2 - 1.2e-15 57.0 0.9 1.7e-15 56.6 0.9 1.3 1 1 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 CBK24101.2 - 7.9e-07 28.8 0.0 1.4e-05 24.8 0.0 2.1 1 1 1 2 2 2 1 Biotin-lipoyl like HlyD_3 PF13437.6 CBK24101.2 - 0.00066 20.3 0.0 0.13 13.0 0.0 2.0 2 0 0 2 2 2 1 HlyD family secretion protein HlyD_D23 PF16576.5 CBK24101.2 - 0.0051 16.1 0.1 1.2 8.3 0.0 2.0 1 1 1 2 2 2 2 Barrel-sandwich domain of CusB or HlyD membrane-fusion RnfC_N PF13375.6 CBK24101.2 - 0.0076 16.2 0.1 0.0095 15.9 0.1 1.2 1 0 0 1 1 1 1 RnfC Barrel sandwich hybrid domain GCV_H PF01597.19 CBK24101.2 - 0.027 14.4 0.1 0.031 14.1 0.1 1.1 1 0 0 1 1 1 0 Glycine cleavage H-protein ATP-synt_ab_Xtn PF16886.5 CBK24101.2 - 0.045 13.6 0.3 0.058 13.3 0.3 1.2 1 1 0 1 1 1 0 ATPsynthase alpha/beta subunit N-term extension PTS_EIIA_1 PF00358.20 CBK24101.2 - 0.047 13.5 0.1 0.11 12.3 0.0 1.6 1 1 1 2 2 2 0 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 PYNP_C PF07831.13 CBK24101.2 - 0.076 12.7 0.1 0.15 11.7 0.1 1.5 2 0 0 2 2 2 0 Pyrimidine nucleoside phosphorylase C-terminal domain NQRA PF05896.11 CBK24101.2 - 0.087 12.2 0.1 0.096 12.1 0.1 1.1 1 0 0 1 1 1 0 Na(+)-translocating NADH-quinone reductase subunit A (NQRA) Mob1_phocein PF03637.17 CBK24102.2 - 3.7e-56 189.8 0.1 4.3e-56 189.5 0.1 1.0 1 0 0 1 1 1 1 Mob1/phocein family TPR_12 PF13424.6 CBK24103.2 - 4.6e-16 58.9 3.9 4.5e-12 46.1 1.4 2.2 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_10 PF13374.6 CBK24103.2 - 1.2e-12 47.3 6.5 7.4e-07 28.8 0.6 3.3 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.28 CBK24103.2 - 7.7e-08 31.8 8.2 1.1e-07 31.3 2.0 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 CBK24103.2 - 8.7e-07 28.6 6.5 5.8e-06 26.0 0.9 2.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 CBK24103.2 - 5e-06 26.2 1.4 9.2e-05 22.2 0.3 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 CBK24103.2 - 2.4e-05 24.2 3.9 2.5e-05 24.1 1.4 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat DUF2225 PF09986.9 CBK24103.2 - 0.0013 18.5 1.2 0.0016 18.2 1.2 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2225) LBP_M PF17385.2 CBK24103.2 - 0.018 14.6 0.1 0.029 13.9 0.1 1.3 1 0 0 1 1 1 0 Lacto-N-biose phosphorylase central domain DUF4404 PF14357.6 CBK24103.2 - 0.035 14.7 0.1 0.074 13.7 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4404) TPR_14 PF13428.6 CBK24103.2 - 0.047 14.5 0.1 3.6 8.7 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.6 CBK24103.2 - 0.49 11.1 2.7 0.57 10.9 0.6 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat HECT PF00632.25 CBK24104.2 - 9.9e-60 202.6 0.0 2.7e-59 201.2 0.0 1.8 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Thioredoxin PF00085.20 CBK24105.2 - 4.5e-21 74.8 0.0 5.9e-21 74.4 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_7 PF13899.6 CBK24105.2 - 9.4e-05 22.5 0.0 0.00049 20.2 0.0 2.0 2 0 0 2 2 2 1 Thioredoxin-like Thioredoxin_2 PF13098.6 CBK24105.2 - 0.00054 20.4 0.2 0.0087 16.5 0.2 2.2 1 1 0 1 1 1 1 Thioredoxin-like domain DUF4083 PF13314.6 CBK24105.2 - 0.014 15.3 1.3 0.032 14.2 1.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4083) AAA_5 PF07728.14 CBK24106.2 - 2.5e-54 183.0 0.0 3.2e-13 49.8 0.0 7.3 7 0 0 7 7 7 5 AAA domain (dynein-related subfamily) AAA_7 PF12775.7 CBK24106.2 - 3.8e-16 59.1 2.8 0.0034 16.9 0.0 5.9 6 0 0 6 6 6 4 P-loop containing dynein motor region AAA_3 PF07726.11 CBK24106.2 - 9.7e-13 48.1 0.0 1.9e-07 31.0 0.0 3.5 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 CBK24106.2 - 5.1e-12 46.0 0.0 0.0077 16.3 0.0 6.2 5 0 0 5 5 5 3 AAA domain AAA_22 PF13401.6 CBK24106.2 - 3e-10 40.5 1.1 0.077 13.3 0.1 6.6 5 2 0 5 5 5 2 AAA domain Dynein_heavy PF03028.15 CBK24106.2 - 3.3e-10 40.1 0.0 6e-05 23.1 0.0 4.3 4 0 0 4 4 4 2 Dynein heavy chain region D6 P-loop domain Sigma54_activat PF00158.26 CBK24106.2 - 3.9e-08 33.2 0.0 0.0053 16.5 0.0 4.6 5 0 0 5 5 5 2 Sigma-54 interaction domain AAA_16 PF13191.6 CBK24106.2 - 6e-06 26.8 0.0 4 7.8 0.0 5.7 5 0 0 5 5 5 1 AAA ATPase domain AAA PF00004.29 CBK24106.2 - 9.9e-06 26.0 0.1 1.5 9.2 0.0 5.4 5 0 0 5 5 4 2 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 CBK24106.2 - 8.8e-05 22.7 0.4 0.94 9.6 0.0 4.7 6 0 0 6 6 6 1 AAA domain AAA_18 PF13238.6 CBK24106.2 - 0.0075 16.8 0.0 42 4.7 0.0 5.0 4 0 0 4 4 4 0 AAA domain AAA_30 PF13604.6 CBK24106.2 - 0.012 15.4 0.0 2.1 8.0 0.0 4.1 5 0 0 5 5 5 0 AAA domain Viral_helicase1 PF01443.18 CBK24106.2 - 0.016 14.9 0.1 2.2 7.9 0.0 3.2 3 0 0 3 3 3 0 Viral (Superfamily 1) RNA helicase ABC_tran PF00005.27 CBK24106.2 - 0.031 14.8 4.7 6.4 7.3 0.0 4.5 4 0 0 4 4 3 0 ABC transporter RNA_helicase PF00910.22 CBK24106.2 - 0.049 14.0 0.0 25 5.3 0.0 4.2 3 0 0 3 3 3 0 RNA helicase PhoLip_ATPase_C PF16212.5 CBK24107.2 - 1.8e-38 132.8 20.0 2.4e-38 132.3 20.0 1.1 1 0 0 1 1 1 1 Phospholipid-translocating P-type ATPase C-terminal Hydrolase PF00702.26 CBK24107.2 - 1.5e-10 41.7 0.0 3.1e-06 27.6 0.0 2.2 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 CBK24107.2 - 0.079 13.1 0.0 0.19 11.9 0.0 1.6 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 CBK24107.2 - 0.19 11.5 0.1 2.7 7.6 0.0 2.1 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase PhoLip_ATPase_N PF16209.5 CBK24108.2 - 2e-14 53.0 0.9 2e-14 53.0 0.9 2.3 3 0 0 3 3 3 1 Phospholipid-translocating ATPase N-terminal E1-E2_ATPase PF00122.20 CBK24108.2 - 2.5e-06 27.1 0.0 7e-06 25.7 0.0 1.7 1 1 0 1 1 1 1 E1-E2 ATPase PHD PF00628.29 CBK24109.2 - 7.3e-07 29.0 4.6 7.3e-07 29.0 4.6 1.9 2 0 0 2 2 2 1 PHD-finger zf-HC5HC2H_2 PF13832.6 CBK24109.2 - 6.3e-05 23.1 0.5 0.0001 22.4 0.5 1.4 1 1 0 1 1 1 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 CBK24109.2 - 0.00023 21.4 1.8 0.0005 20.3 1.9 1.7 1 1 0 1 1 1 1 PHD-like zinc-binding domain Zf_RING PF16744.5 CBK24109.2 - 0.019 15.1 1.2 0.019 15.1 1.2 1.7 1 1 0 1 1 1 0 KIAA1045 RING finger zf-rbx1 PF12678.7 CBK24109.2 - 0.09 13.1 2.8 0.22 11.9 2.8 1.6 1 0 0 1 1 1 0 RING-H2 zinc finger domain C1_1 PF00130.22 CBK24109.2 - 0.11 12.4 4.1 0.1 12.5 1.0 2.2 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-RING_2 PF13639.6 CBK24109.2 - 0.14 12.5 8.1 0.29 11.5 8.1 1.5 1 0 0 1 1 1 0 Ring finger domain RRM_1 PF00076.22 CBK24110.2 - 1.3e-24 85.8 0.1 3.9e-20 71.4 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 CBK24110.2 - 0.00018 21.1 0.0 0.00036 20.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 CBK24110.2 - 0.018 15.1 0.0 0.18 11.9 0.0 2.2 2 0 0 2 2 2 0 RNA binding motif DUF4813 PF16072.5 CBK24110.2 - 0.34 10.5 18.4 0.5 10.0 18.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4813) Cyclin_N PF00134.23 CBK24111.2 - 3.2e-16 59.2 0.0 8.7e-16 57.8 0.0 1.6 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cpn60_TCP1 PF00118.24 CBK24112.2 - 2.5e-98 329.8 16.7 3.4e-98 329.4 16.7 1.2 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Nup35_RRM_2 PF14605.6 CBK24113.2 - 0.00036 20.5 0.1 0.00066 19.6 0.1 1.4 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RRM_1 PF00076.22 CBK24113.2 - 0.0012 18.6 0.0 0.019 14.8 0.0 2.4 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 CBK24113.2 - 0.048 13.5 0.0 0.095 12.6 0.0 1.4 1 0 0 1 1 1 0 Occluded RNA-recognition motif Sec7_N PF12783.7 CBK24115.2 - 7.4e-25 87.7 3.8 7.4e-25 87.7 3.8 2.8 3 0 0 3 3 3 1 Guanine nucleotide exchange factor in Golgi transport N-terminal Raftlin PF15250.6 CBK24115.2 - 0.028 13.2 2.0 0.041 12.6 2.0 1.3 1 0 0 1 1 1 0 Raftlin TMEM208_SND2 PF05620.11 CBK24115.2 - 0.13 12.0 0.0 0.13 12.0 0.0 2.2 2 0 0 2 2 2 0 SRP-independent targeting protein 2/TMEM208 Macoilin PF09726.9 CBK24115.2 - 2.1 6.8 7.0 2.9 6.3 7.0 1.1 1 0 0 1 1 1 0 Macoilin family SMC_N PF02463.19 CBK24116.2 - 2.4e-78 262.6 4.1 8.9e-78 260.7 4.1 1.9 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 CBK24116.2 - 7.3e-22 77.9 0.0 2.7e-21 76.0 0.0 2.1 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 CBK24116.2 - 6e-15 55.8 5.8 4.3e-07 30.0 0.2 2.6 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 CBK24116.2 - 2.4e-14 54.3 2.4 2.4e-14 54.3 2.4 6.0 2 2 1 4 4 4 1 AAA domain AAA_15 PF13175.6 CBK24116.2 - 2.3e-12 47.3 0.3 2.3e-12 47.3 0.3 3.6 2 2 1 3 3 3 1 AAA ATPase domain AAA_29 PF13555.6 CBK24116.2 - 5.2e-06 26.1 0.0 1e-05 25.1 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_tran PF00005.27 CBK24116.2 - 0.11 13.0 0.0 0.11 13.0 0.0 6.3 3 2 0 3 3 3 0 ABC transporter Baculo_PEP_C PF04513.12 CBK24116.2 - 0.16 12.0 17.7 0.32 11.0 0.2 5.1 2 2 2 5 5 5 0 Baculovirus polyhedron envelope protein, PEP, C terminus AAA PF00004.29 CBK24116.2 - 0.56 10.6 5.5 24 5.4 0.0 4.6 4 0 0 4 4 4 0 ATPase family associated with various cellular activities (AAA) DNA_pol3_a_NI PF14480.6 CBK24117.2 - 0.038 14.0 0.2 1.7 8.7 0.0 2.3 2 0 0 2 2 2 0 DNA polymerase III polC-type N-terminus I Beach PF02138.18 CBK24118.2 - 5.9e-92 308.0 0.0 8.5e-92 307.4 0.0 1.2 1 0 0 1 1 1 1 Beige/BEACH domain Shisa PF13908.6 CBK24120.2 - 0.0028 17.9 0.3 0.0028 17.9 0.3 2.5 1 1 1 3 3 3 1 Wnt and FGF inhibitory regulator FAM176 PF14851.6 CBK24120.2 - 0.093 12.4 0.0 0.2 11.3 0.0 1.5 1 0 0 1 1 1 0 FAM176 family Tweety PF04906.13 CBK24120.2 - 0.11 11.1 0.5 0.16 10.6 0.5 1.1 1 0 0 1 1 1 0 Tweety L51_S25_CI-B8 PF05047.16 CBK24121.2 - 3.6e-10 39.6 0.3 5.9e-10 38.9 0.3 1.4 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain Adap_comp_sub PF00928.21 CBK24123.2 - 2.4e-81 273.0 0.0 3e-81 272.7 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 CBK24123.2 - 3.5e-09 36.7 0.2 6.3e-09 35.9 0.2 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain muHD PF10291.9 CBK24123.2 - 0.0028 17.2 0.0 0.0044 16.5 0.0 1.3 1 0 0 1 1 1 1 Muniscin C-terminal mu homology domain Longin PF13774.6 CBK24123.2 - 0.062 13.4 0.1 0.14 12.2 0.1 1.6 1 0 0 1 1 1 0 Regulated-SNARE-like domain SNF2_N PF00176.23 CBK24124.2 - 7.4e-59 199.2 0.0 1.8e-58 197.9 0.0 1.5 1 1 0 1 1 1 1 SNF2 family N-terminal domain zf-HC5HC2H_2 PF13832.6 CBK24124.2 - 4.6e-21 75.1 7.4 4.6e-21 75.1 7.4 2.2 2 0 0 2 2 2 1 PHD-zinc-finger like domain Helicase_C PF00271.31 CBK24124.2 - 1.4e-20 73.7 0.0 3.8e-20 72.3 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-HC5HC2H PF13771.6 CBK24124.2 - 3e-17 62.6 2.9 3e-17 62.6 2.9 2.7 2 1 1 3 3 3 1 PHD-like zinc-binding domain ResIII PF04851.15 CBK24124.2 - 3.8e-08 33.5 0.0 1.1e-07 32.0 0.0 1.9 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit PHD_2 PF13831.6 CBK24124.2 - 3e-06 26.7 9.5 3e-06 26.7 9.5 2.9 3 0 0 3 3 3 1 PHD-finger HDA2-3 PF11496.8 CBK24124.2 - 4.4e-06 26.1 0.1 1.4e-05 24.5 0.1 1.8 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 DEAD PF00270.29 CBK24124.2 - 0.00013 21.7 0.0 0.00029 20.7 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase PHD PF00628.29 CBK24124.2 - 0.00039 20.3 15.1 0.00039 20.3 15.1 3.0 3 0 0 3 3 3 1 PHD-finger EGF_2 PF07974.13 CBK24125.2 - 0.039 14.3 11.0 0.12 12.8 11.0 1.9 1 0 0 1 1 1 0 EGF-like domain GAGA_bind PF06217.12 CBK24126.2 - 0.077 13.3 5.8 0.12 12.6 5.8 1.4 1 0 0 1 1 1 0 GAGA binding protein-like family CDC27 PF09507.10 CBK24126.2 - 4.4 6.6 30.0 6.5 6.0 30.0 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 RAMP4 PF06624.12 CBK24127.2 - 1.6e-18 66.5 0.0 1.8e-18 66.3 0.0 1.1 1 0 0 1 1 1 1 Ribosome associated membrane protein RAMP4 DUF1206 PF06724.11 CBK24127.2 - 0.087 12.9 0.1 0.11 12.6 0.1 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1206) RtcB PF01139.17 CBK24128.2 - 2.3e-144 481.6 0.1 2.8e-144 481.3 0.1 1.1 1 0 0 1 1 1 1 tRNA-splicing ligase RtcB Cytochrom_c3_2 PF14537.6 CBK24128.2 - 0.063 13.7 0.4 0.14 12.7 0.4 1.5 1 0 0 1 1 1 0 Cytochrome c3 Pro_isomerase PF00160.21 CBK24129.2 - 1.4e-31 109.9 0.0 1.4e-31 109.9 0.0 1.5 2 0 0 2 2 2 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Paf1 PF03985.13 CBK24129.2 - 0.0018 17.3 0.2 0.0022 17.1 0.2 1.0 1 0 0 1 1 1 1 Paf1 SelP_N PF04592.14 CBK24129.2 - 0.069 12.5 14.5 0.093 12.1 14.5 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region TFIIE-A_C PF11521.8 CBK24129.2 - 0.49 10.7 8.8 7.5 6.9 8.1 2.2 2 0 0 2 2 2 0 C-terminal general transcription factor TFIIE alpha Zip PF02535.22 CBK24129.2 - 0.89 8.7 5.4 1.1 8.4 5.4 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Presenilin PF01080.17 CBK24129.2 - 1.5 7.5 4.0 1.7 7.3 4.0 1.1 1 0 0 1 1 1 0 Presenilin NPR3 PF03666.13 CBK24129.2 - 2.7 6.7 6.1 3.3 6.4 6.1 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Strabismus PF06638.11 CBK24129.2 - 4.3 5.9 5.2 5.6 5.5 5.2 1.1 1 0 0 1 1 1 0 Strabismus protein Med7 PF05983.11 CBK24130.2 - 0.00091 19.4 5.0 0.21 11.6 5.0 2.0 1 1 0 1 1 1 1 MED7 protein FYVE PF01363.21 CBK24131.2 - 7.1e-16 58.1 7.3 1.6e-15 57.0 7.3 1.6 1 0 0 1 1 1 1 FYVE zinc finger GAS PF13851.6 CBK24131.2 - 0.00071 19.0 21.9 0.00071 19.0 21.9 1.7 2 0 0 2 2 2 1 Growth-arrest specific micro-tubule binding ERM PF00769.19 CBK24131.2 - 0.0012 18.8 20.0 0.0015 18.4 20.0 1.1 1 0 0 1 1 1 1 Ezrin/radixin/moesin family zf-C4H2 PF10146.9 CBK24131.2 - 0.0018 18.6 14.5 0.0024 18.2 14.5 1.1 1 0 0 1 1 1 1 Zinc finger-containing protein THP2 PF09432.10 CBK24131.2 - 0.017 15.1 8.6 0.031 14.3 8.6 1.5 1 0 0 1 1 1 0 Tho complex subunit THP2 DUF3450 PF11932.8 CBK24131.2 - 0.12 11.6 17.4 0.21 10.9 17.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) DUF4890 PF16231.5 CBK24131.2 - 0.13 12.8 11.9 0.23 11.9 11.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4890) FlaC_arch PF05377.11 CBK24131.2 - 0.19 12.1 15.9 0.37 11.2 2.4 2.9 3 0 0 3 3 2 0 Flagella accessory protein C (FlaC) COQ7 PF03232.13 CBK24131.2 - 0.25 11.1 7.0 0.4 10.4 7.0 1.4 1 0 0 1 1 1 0 Ubiquinone biosynthesis protein COQ7 DUF4349 PF14257.6 CBK24131.2 - 0.33 10.4 14.8 0.27 10.6 10.5 2.7 2 2 0 2 2 2 0 Domain of unknown function (DUF4349) ATG16 PF08614.11 CBK24131.2 - 0.51 10.5 29.9 0.057 13.7 23.0 2.0 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) Fez1 PF06818.15 CBK24131.2 - 0.53 10.7 23.2 1.5 9.2 23.2 1.7 1 1 0 1 1 1 0 Fez1 Spc7 PF08317.11 CBK24131.2 - 0.63 8.9 19.9 1.3 7.8 19.9 1.5 1 0 0 1 1 1 0 Spc7 kinetochore protein HAUS-augmin3 PF14932.6 CBK24131.2 - 0.65 9.5 19.8 0.48 10.0 18.3 1.5 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 3 DUF4407 PF14362.6 CBK24131.2 - 0.75 9.1 10.0 1 8.7 10.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF4201 PF13870.6 CBK24131.2 - 0.78 9.5 21.1 1.5 8.5 21.0 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4201) V_ATPase_I PF01496.19 CBK24131.2 - 1.3 6.8 10.6 1.5 6.7 10.6 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family HypA PF01155.19 CBK24131.2 - 5.3 7.1 11.0 0.5 10.4 1.0 2.8 2 1 1 3 3 3 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Seryl_tRNA_N PF02403.22 CBK24131.2 - 5.5 7.3 21.4 0.6 10.4 14.7 2.3 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Mod_r PF07200.13 CBK24131.2 - 5.9 7.0 26.8 2.7 8.1 21.6 2.3 2 1 1 3 3 2 0 Modifier of rudimentary (Mod(r)) protein FapA PF03961.13 CBK24131.2 - 6.6 5.2 12.5 12 4.4 12.5 1.4 1 0 0 1 1 1 0 Flagellar Assembly Protein A PKcGMP_CC PF16808.5 CBK24131.2 - 9.4 6.2 17.0 0.45 10.4 2.6 3.5 3 1 0 3 3 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase HC2 PF07382.11 CBK24132.2 - 0.087 12.9 52.6 3.4 7.7 21.1 3.1 1 1 1 2 2 2 0 Histone H1-like nucleoprotein HC2 tRNA-synt_1 PF00133.22 CBK24133.2 - 5.2e-135 451.0 0.0 6.3e-74 249.3 0.0 2.0 1 1 1 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.11 CBK24133.2 - 6.2e-14 51.5 5.5 2.6e-07 29.7 0.1 4.2 4 1 0 4 4 4 3 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.6 CBK24133.2 - 0.0021 17.6 0.0 2.4 7.7 0.0 2.9 1 1 1 2 2 2 2 Leucyl-tRNA synthetase, Domain 2 Anticodon_1 PF08264.13 CBK24133.2 - 0.03 14.3 0.0 0.051 13.5 0.0 1.4 1 0 0 1 1 1 0 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.19 CBK24133.2 - 0.14 11.5 0.0 2.6 7.3 0.0 2.2 2 0 0 2 2 2 0 tRNA synthetases class I (C) catalytic domain tRNA-synt_1c PF00749.21 CBK24133.2 - 0.4 9.5 1.3 3.1 6.6 0.2 2.6 3 0 0 3 3 3 0 tRNA synthetases class I (E and Q), catalytic domain MORN PF02493.20 CBK24134.2 - 0.043 13.7 0.0 0.17 11.8 0.1 2.0 2 0 0 2 2 2 0 MORN repeat LRR_5 PF13306.6 CBK24134.2 - 0.074 13.0 16.8 0.064 13.2 3.7 4.6 2 1 2 5 5 5 0 BspA type Leucine rich repeat region (6 copies) ABC_tran PF00005.27 CBK24135.2 - 1.2e-72 242.9 1.0 9.8e-37 126.5 0.0 2.8 3 0 0 3 3 2 2 ABC transporter ABC_membrane PF00664.23 CBK24135.2 - 7.3e-55 186.5 8.6 5.8e-28 98.3 0.5 2.3 2 0 0 2 2 2 2 ABC transporter transmembrane region AAA_16 PF13191.6 CBK24135.2 - 4.9e-12 46.6 0.1 0.00017 22.0 0.0 3.2 2 1 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 CBK24135.2 - 2.8e-10 40.6 2.4 0.0041 17.4 0.0 4.2 2 2 0 2 2 2 2 AAA domain SMC_N PF02463.19 CBK24135.2 - 4.6e-09 36.0 8.2 0.0045 16.4 0.0 4.4 4 1 1 5 5 4 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 CBK24135.2 - 1.3e-08 34.4 0.3 0.0036 17.0 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 CBK24135.2 - 1.7e-08 34.6 0.0 0.009 15.9 0.0 2.6 2 0 0 2 2 2 2 RsgA GTPase AAA_21 PF13304.6 CBK24135.2 - 2.3e-08 34.2 0.4 0.76 9.5 0.1 4.4 4 0 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA PF00004.29 CBK24135.2 - 8.5e-08 32.7 1.5 0.0013 19.2 0.0 4.2 3 2 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) G-alpha PF00503.20 CBK24135.2 - 8.6e-07 28.4 0.0 0.025 13.8 0.0 2.6 2 0 0 2 2 2 2 G-protein alpha subunit ABC_ATPase PF09818.9 CBK24135.2 - 1.1e-06 27.7 0.7 0.034 13.0 0.0 3.1 3 0 0 3 3 3 2 Predicted ATPase of the ABC class AAA_25 PF13481.6 CBK24135.2 - 2.2e-06 27.4 0.3 0.54 9.8 0.0 4.0 4 0 0 4 4 4 2 AAA domain AAA_23 PF13476.6 CBK24135.2 - 2.8e-06 28.0 6.0 0.031 14.8 0.0 3.5 3 0 0 3 3 3 2 AAA domain AAA_30 PF13604.6 CBK24135.2 - 4.2e-06 26.6 0.7 0.26 11.0 0.2 3.8 2 2 0 2 2 2 2 AAA domain AAA_5 PF07728.14 CBK24135.2 - 5.8e-06 26.3 0.9 1.4 9.0 0.0 4.7 5 0 0 5 5 4 1 AAA domain (dynein-related subfamily) RNA_helicase PF00910.22 CBK24135.2 - 8.6e-06 26.1 0.1 0.26 11.7 0.0 3.7 4 0 0 4 4 3 2 RNA helicase SbcCD_C PF13558.6 CBK24135.2 - 1.5e-05 25.1 4.6 0.063 13.5 0.8 3.8 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_18 PF13238.6 CBK24135.2 - 3.1e-05 24.5 0.5 0.67 10.5 0.1 4.0 4 0 0 4 4 4 2 AAA domain AAA_7 PF12775.7 CBK24135.2 - 8.5e-05 22.1 0.9 0.1 12.1 0.0 2.8 3 0 0 3 3 3 2 P-loop containing dynein motor region IstB_IS21 PF01695.17 CBK24135.2 - 0.0001 22.1 0.2 1.5 8.5 0.0 4.0 5 0 0 5 5 3 1 IstB-like ATP binding protein Rad17 PF03215.15 CBK24135.2 - 0.00013 22.0 0.0 0.11 12.4 0.0 2.8 2 0 0 2 2 2 1 Rad17 P-loop domain DEAD PF00270.29 CBK24135.2 - 0.00018 21.4 0.2 0.059 13.1 0.0 3.2 2 2 0 2 2 2 1 DEAD/DEAH box helicase MMR_HSR1 PF01926.23 CBK24135.2 - 0.00021 21.3 0.2 0.63 10.1 0.0 3.2 2 0 0 2 2 2 1 50S ribosome-binding GTPase PRK PF00485.18 CBK24135.2 - 0.0006 19.6 0.1 0.4 10.4 0.1 2.5 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family NB-ARC PF00931.22 CBK24135.2 - 0.00065 19.0 0.1 0.76 8.9 0.0 2.7 2 0 0 2 2 2 2 NB-ARC domain AAA_33 PF13671.6 CBK24135.2 - 0.0015 18.7 0.3 2.1 8.5 0.1 3.0 2 1 0 2 2 2 1 AAA domain AAA_15 PF13175.6 CBK24135.2 - 0.0018 18.1 6.0 0.7 9.5 0.0 3.1 2 1 0 2 2 2 1 AAA ATPase domain PhoH PF02562.16 CBK24135.2 - 0.002 17.6 0.1 2.4 7.6 0.0 3.3 3 0 0 3 3 3 1 PhoH-like protein AAA_24 PF13479.6 CBK24135.2 - 0.002 17.9 0.3 1.5 8.5 0.2 3.0 2 2 0 2 2 2 1 AAA domain Sigma54_activat PF00158.26 CBK24135.2 - 0.0026 17.5 0.1 4.6 6.9 0.0 3.5 4 0 0 4 4 3 0 Sigma-54 interaction domain ATP_bind_1 PF03029.17 CBK24135.2 - 0.0043 16.9 0.5 0.42 10.4 0.0 2.9 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein Mg_chelatase PF01078.21 CBK24135.2 - 0.0074 15.7 0.0 0.52 9.7 0.0 2.5 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI MeaB PF03308.16 CBK24135.2 - 0.0075 15.3 0.0 0.74 8.7 0.0 2.4 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB KAP_NTPase PF07693.14 CBK24135.2 - 0.0084 15.4 0.0 0.58 9.3 0.0 3.4 3 1 0 3 3 3 1 KAP family P-loop domain Zeta_toxin PF06414.12 CBK24135.2 - 0.013 14.8 0.0 4.4 6.5 0.0 2.6 2 0 0 2 2 2 0 Zeta toxin Roc PF08477.13 CBK24135.2 - 0.015 15.5 0.0 6.3 7.0 0.0 3.5 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase NACHT PF05729.12 CBK24135.2 - 0.02 14.8 0.2 2 8.3 0.1 2.9 2 0 0 2 2 2 0 NACHT domain APS_kinase PF01583.20 CBK24135.2 - 0.029 14.3 0.1 3.1 7.7 0.0 2.9 2 0 0 2 2 2 0 Adenylylsulphate kinase AAA_14 PF13173.6 CBK24135.2 - 0.048 13.7 0.0 15 5.6 0.0 3.1 3 0 0 3 3 2 0 AAA domain NTPase_1 PF03266.15 CBK24135.2 - 0.051 13.5 0.5 19 5.2 0.2 3.0 3 0 0 3 3 2 0 NTPase RED_N PF07808.13 CBK24135.2 - 0.053 13.1 3.3 0.096 12.2 3.3 1.4 1 0 0 1 1 1 0 RED-like protein N-terminal region AAA_19 PF13245.6 CBK24135.2 - 0.056 13.8 1.6 9.2 6.6 0.0 3.8 3 1 0 3 3 3 0 AAA domain DUF87 PF01935.17 CBK24135.2 - 0.07 13.2 6.8 3 7.9 4.5 3.1 2 1 0 2 2 2 0 Helicase HerA, central domain AAA_28 PF13521.6 CBK24135.2 - 0.083 13.1 0.1 5.7 7.2 0.0 2.7 2 0 0 2 2 2 0 AAA domain ATP-synt_ab PF00006.25 CBK24135.2 - 0.091 12.4 0.1 5.8 6.5 0.0 2.4 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain T2SSE PF00437.20 CBK24135.2 - 0.097 11.7 0.2 0.74 8.8 0.1 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein MobB PF03205.14 CBK24135.2 - 0.11 12.4 0.1 5.1 7.0 0.1 2.6 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B DUF2368 PF10166.9 CBK24135.2 - 0.14 11.8 0.0 0.62 9.7 0.0 2.2 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2368) Raftlin PF15250.6 CBK24135.2 - 0.17 10.6 2.6 0.29 9.8 2.6 1.2 1 0 0 1 1 1 0 Raftlin UPF0542 PF15086.6 CBK24135.2 - 1.7 8.7 7.0 9 6.3 0.1 4.2 4 0 0 4 4 4 0 Uncharacterised protein family UPF0542 He_PIG PF05345.12 CBK24137.2 - 0.0022 18.1 0.4 0.0022 18.1 0.4 3.4 3 0 0 3 3 3 1 Putative Ig domain Pertactin PF03212.14 CBK24137.2 - 0.078 12.9 0.9 0.18 11.7 0.9 1.6 1 0 0 1 1 1 0 Pertactin PIF6 PF05341.11 CBK24137.2 - 0.087 13.0 0.1 0.52 10.5 0.0 2.3 2 0 0 2 2 2 0 Per os infectivity factor 6 DUF563 PF04577.14 CBK24139.2 - 3.6e-17 63.2 0.1 8.2e-17 62.0 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF563) SPX PF03105.19 CBK24140.2 - 2.4e-22 80.4 3.8 6e-10 39.6 0.2 3.1 1 1 2 3 3 3 3 SPX domain Phasin PF05597.11 CBK24140.2 - 0.012 15.6 0.0 3.1 7.8 0.0 2.7 2 1 0 3 3 3 0 Poly(hydroxyalcanoate) granule associated protein (phasin) EF-hand_7 PF13499.6 CBK24140.2 - 0.11 12.9 0.6 0.89 10.1 0.3 2.5 2 1 0 2 2 2 0 EF-hand domain pair EXS PF03124.14 CBK24141.2 - 3.6e-47 161.3 12.6 1.2e-46 159.6 12.6 1.7 1 1 0 1 1 1 1 EXS family TFIIE_beta PF02186.15 CBK24142.2 - 0.069 13.4 0.0 0.24 11.7 0.0 1.9 1 0 0 1 1 1 0 TFIIE beta subunit core domain Aminotran_1_2 PF00155.21 CBK24143.2 - 9e-77 258.7 0.0 1e-76 258.5 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II FAM150 PF15129.6 CBK24144.2 - 0.092 12.9 0.5 0.88 9.7 0.1 2.4 2 0 0 2 2 2 0 FAM150 family NUDIX PF00293.28 CBK24146.2 - 4.9e-09 36.3 0.1 5.9e-09 36.1 0.1 1.1 1 0 0 1 1 1 1 NUDIX domain EMP70 PF02990.16 CBK24147.2 - 1.7e-44 152.4 0.0 2.1e-44 152.1 0.0 1.0 1 0 0 1 1 1 1 Endomembrane protein 70 Spt20 PF12090.8 CBK24147.2 - 0.21 11.2 0.1 0.33 10.5 0.1 1.2 1 0 0 1 1 1 0 Spt20 family Hamartin PF04388.12 CBK24148.2 - 0.0017 17.1 40.5 0.0024 16.6 40.5 1.2 1 0 0 1 1 1 1 Hamartin protein STAT1_TAZ2bind PF12162.8 CBK24148.2 - 0.0086 15.6 0.0 2.2 8.0 0.0 2.7 2 0 0 2 2 2 2 STAT1 TAZ2 binding domain XG_FTase PF03254.13 CBK24149.2 - 5.4e-06 25.3 0.0 0.019 13.6 0.0 2.2 2 0 0 2 2 2 2 Xyloglucan fucosyltransferase BRCT PF00533.26 CBK24149.2 - 0.00011 22.4 0.0 0.00097 19.5 0.0 2.4 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain NodZ PF05830.11 CBK24149.2 - 0.0012 17.7 0.1 0.38 9.5 0.0 2.3 2 0 0 2 2 2 2 Nodulation protein Z (NodZ) FHA PF00498.26 CBK24149.2 - 0.0032 17.8 0.1 0.013 15.8 0.1 2.1 1 0 0 1 1 1 1 FHA domain PTCB-BRCT PF12738.7 CBK24149.2 - 0.0068 16.3 0.0 0.015 15.2 0.0 1.6 1 0 0 1 1 1 1 twin BRCT domain RTT107_BRCT_5 PF16770.5 CBK24149.2 - 0.067 13.1 0.0 0.16 11.8 0.0 1.6 1 0 0 1 1 1 0 Regulator of Ty1 transposition protein 107 BRCT domain NIBRIN_BRCT_II PF16508.5 CBK24149.2 - 0.086 13.2 0.0 0.26 11.6 0.0 1.8 1 0 0 1 1 1 0 Second BRCT domain on Nijmegen syndrome breakage protein TBPIP_N PF15517.6 CBK24149.2 - 0.1 12.6 0.0 0.25 11.4 0.0 1.6 1 0 0 1 1 1 0 TBP-interacting protein N-terminus Tetraspanin PF00335.20 CBK24150.2 - 7.8e-15 55.2 17.8 1.1e-14 54.7 17.8 1.2 1 0 0 1 1 1 1 Tetraspanin family RSN1_TM PF13967.6 CBK24150.2 - 0.013 15.3 3.8 0.051 13.3 3.8 1.9 1 1 0 1 1 1 0 Late exocytosis, associated with Golgi transport ODV-E18 PF10717.9 CBK24150.2 - 0.044 13.7 5.3 1.2 9.0 1.1 2.6 3 0 0 3 3 3 0 Occlusion-derived virus envelope protein ODV-E18 DUF1372 PF07116.11 CBK24150.2 - 0.75 10.0 3.6 1.3 9.3 0.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1372) Exo_endo_phos PF03372.23 CBK24151.2 - 3.7e-05 23.4 0.0 6e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Methyltransf_25 PF13649.6 CBK24152.2 - 7.7e-06 26.5 0.0 1.1e-05 26.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CBK24152.2 - 8.7e-05 23.1 0.0 0.00013 22.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 CBK24152.2 - 0.00033 20.1 0.0 0.00048 19.5 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 CBK24152.2 - 0.0058 17.4 0.0 0.0083 16.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Fer2_3 PF13085.6 CBK24153.2 - 1.1e-33 115.4 0.0 2.1e-33 114.6 0.0 1.5 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer4_8 PF13183.6 CBK24153.2 - 5e-09 36.5 10.7 1.6e-08 34.9 7.1 2.9 1 1 2 3 3 3 2 4Fe-4S dicluster domain Fer4_17 PF13534.6 CBK24153.2 - 2e-08 34.6 6.5 2e-08 34.6 6.5 2.4 3 0 0 3 3 3 1 4Fe-4S dicluster domain Fer4_10 PF13237.6 CBK24153.2 - 2.7e-07 30.6 3.4 2.7e-07 30.6 3.4 2.1 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer2 PF00111.27 CBK24153.2 - 3.7e-05 23.6 0.2 3.7e-05 23.6 0.2 2.1 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fer4_7 PF12838.7 CBK24153.2 - 0.0034 18.0 4.9 0.0034 18.0 4.9 2.7 2 2 0 2 2 2 1 4Fe-4S dicluster domain Fer4_9 PF13187.6 CBK24153.2 - 0.064 13.4 12.5 0.033 14.4 8.0 2.5 2 1 0 2 2 2 0 4Fe-4S dicluster domain Herpes_UL51 PF04540.13 CBK24153.2 - 0.11 12.2 0.0 0.2 11.4 0.0 1.4 1 0 0 1 1 1 0 Herpesvirus UL51 protein 6PGD PF00393.19 CBK24154.2 - 1.7e-49 168.7 0.0 2.3e-49 168.3 0.0 1.1 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.15 CBK24154.2 - 2.7e-18 66.6 0.0 4.6e-18 65.9 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase ATP_bind_1 PF03029.17 CBK24155.2 - 2.5e-71 240.3 0.0 2.8e-71 240.1 0.0 1.0 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_18 PF13238.6 CBK24155.2 - 0.00018 22.0 0.0 0.00037 21.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 CBK24155.2 - 0.0035 17.8 0.0 0.01 16.2 0.0 1.7 2 0 0 2 2 2 1 AAA ATPase domain AAA_30 PF13604.6 CBK24155.2 - 0.0042 16.8 0.0 0.0068 16.1 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 CBK24155.2 - 0.0043 16.8 0.0 0.0094 15.7 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain CLP1_P PF16575.5 CBK24155.2 - 0.0086 15.9 0.0 0.015 15.1 0.0 1.3 1 0 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_22 PF13401.6 CBK24155.2 - 0.06 13.6 0.0 0.12 12.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 CBK24155.2 - 0.063 13.8 0.0 0.1 13.1 0.0 1.4 1 0 0 1 1 1 0 ABC transporter AAA_17 PF13207.6 CBK24155.2 - 0.068 13.6 0.1 0.25 11.8 0.0 1.9 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 CBK24155.2 - 0.07 13.5 0.0 0.15 12.4 0.0 1.6 1 0 0 1 1 1 0 RNA helicase T2SSE PF00437.20 CBK24155.2 - 0.074 12.1 0.0 0.11 11.5 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein Thymidylate_kin PF02223.17 CBK24155.2 - 0.13 11.9 0.0 0.21 11.3 0.0 1.3 1 0 0 1 1 1 0 Thymidylate kinase RsgA_GTPase PF03193.16 CBK24155.2 - 0.14 12.1 0.0 3.7 7.4 0.0 2.7 3 0 0 3 3 3 0 RsgA GTPase AAA_33 PF13671.6 CBK24155.2 - 0.14 12.3 0.0 0.52 10.5 0.0 1.9 2 0 0 2 2 2 0 AAA domain G-alpha PF00503.20 CBK24155.2 - 0.15 11.2 0.0 0.31 10.2 0.0 1.4 1 0 0 1 1 1 0 G-protein alpha subunit tRNA_int_endo PF01974.17 CBK24156.2 - 1.2e-16 60.5 0.3 1.5e-16 60.2 0.3 1.1 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain Pkinase PF00069.25 CBK24157.2 - 0.00058 19.3 0.0 0.00064 19.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase PF00069.25 CBK24159.2 - 1.8e-50 171.8 0.0 3.1e-50 171.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBK24159.2 - 7.2e-27 94.3 0.0 1.4e-26 93.4 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase PCI PF01399.27 CBK24159.2 - 2.6e-09 37.5 0.1 4.5e-07 30.3 0.0 3.3 3 0 0 3 3 3 1 PCI domain Haspin_kinase PF12330.8 CBK24159.2 - 1.7e-05 24.0 0.8 3.8e-05 22.8 0.8 1.5 1 0 0 1 1 1 1 Haspin like kinase domain RPN5_C PF18098.1 CBK24159.2 - 2.2e-05 24.5 2.7 5e-05 23.3 2.7 1.7 1 0 0 1 1 1 1 26S proteasome regulatory subunit RPN5 C-terminal domain Kinase-like PF14531.6 CBK24159.2 - 0.00011 21.6 0.0 0.00019 20.8 0.0 1.4 1 0 0 1 1 1 1 Kinase-like MmgE_PrpD PF03972.14 CBK24159.2 - 0.018 13.6 0.0 0.062 11.8 0.0 1.9 2 0 0 2 2 2 0 MmgE/PrpD family DUF1829 PF08862.10 CBK24159.2 - 0.034 14.6 0.2 0.15 12.6 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function DUF1829 Pkinase_fungal PF17667.1 CBK24159.2 - 0.069 11.9 0.3 0.25 10.0 0.2 1.8 2 0 0 2 2 2 0 Fungal protein kinase AAA_5 PF07728.14 CBK24160.2 - 6.3e-54 181.7 0.0 1e-12 48.3 0.0 7.3 7 0 0 7 7 7 5 AAA domain (dynein-related subfamily) PRELI PF04707.14 CBK24160.2 - 5.3e-26 91.3 0.0 1.3e-25 90.0 0.0 1.7 1 0 0 1 1 1 1 PRELI-like family AAA_7 PF12775.7 CBK24160.2 - 2.2e-16 59.9 0.2 0.0024 17.4 0.0 6.1 6 0 0 6 6 6 4 P-loop containing dynein motor region AAA_3 PF07726.11 CBK24160.2 - 1.3e-11 44.5 0.0 3.6e-07 30.1 0.0 3.2 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) Dynein_heavy PF03028.15 CBK24160.2 - 4.7e-11 42.8 0.0 9.1e-06 25.8 0.0 4.1 3 0 0 3 3 3 2 Dynein heavy chain region D6 P-loop domain AAA_14 PF13173.6 CBK24160.2 - 5.7e-11 42.6 0.0 0.0058 16.7 0.0 5.4 4 0 0 4 4 4 2 AAA domain AAA_22 PF13401.6 CBK24160.2 - 2e-10 41.0 0.9 0.18 12.1 0.1 6.6 5 2 0 5 5 5 3 AAA domain AAA_16 PF13191.6 CBK24160.2 - 4.3e-06 27.2 0.0 1.9 8.8 0.0 5.7 5 0 0 5 5 5 1 AAA ATPase domain AAA PF00004.29 CBK24160.2 - 5.3e-06 26.9 0.0 0.32 11.4 0.0 4.9 4 0 0 4 4 4 2 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 CBK24160.2 - 9.5e-05 22.6 0.0 0.66 10.1 0.0 4.2 5 0 0 5 5 4 1 AAA domain AAA_18 PF13238.6 CBK24160.2 - 0.0088 16.6 0.0 24 5.5 0.0 4.6 3 0 0 3 3 3 0 AAA domain RNA_helicase PF00910.22 CBK24160.2 - 0.029 14.8 0.5 12 6.3 0.0 4.5 4 0 0 4 4 4 0 RNA helicase AAA_30 PF13604.6 CBK24160.2 - 0.029 14.1 0.0 5.7 6.6 0.0 3.9 4 0 0 4 4 4 0 AAA domain Viral_helicase1 PF01443.18 CBK24160.2 - 0.065 13.0 0.0 2.5 7.8 0.0 3.1 3 0 0 3 3 3 0 Viral (Superfamily 1) RNA helicase ABC_tran PF00005.27 CBK24160.2 - 0.067 13.7 0.0 12 6.4 0.0 3.2 2 0 0 2 2 2 0 ABC transporter CodY PF06018.14 CBK24160.2 - 0.08 12.4 2.7 0.47 9.9 0.7 3.1 2 0 0 2 2 2 0 CodY GAF-like domain AAA_24 PF13479.6 CBK24160.2 - 0.097 12.4 2.3 22 4.7 0.0 4.3 5 0 0 5 5 5 0 AAA domain TsaE PF02367.17 CBK24160.2 - 0.11 12.4 0.0 13 5.8 0.0 3.4 3 0 0 3 3 3 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE RRM_1 PF00076.22 CBK24161.2 - 4.7e-21 74.4 0.0 8.5e-21 73.6 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) OB_RNB PF08206.11 CBK24161.2 - 0.16 11.7 0.1 0.33 10.7 0.1 1.4 1 0 0 1 1 1 0 Ribonuclease B OB domain MRP-S33 PF08293.11 CBK24161.2 - 1.1 9.5 4.3 47 4.3 4.3 2.9 1 1 0 1 1 1 0 Mitochondrial ribosomal subunit S27 VPS13 PF16908.5 CBK24162.2 - 3.2e-19 69.7 13.6 1e-16 61.5 4.3 3.8 3 1 0 4 4 4 2 Vacuolar sorting-associated protein 13, N-terminal VPS13_mid_rpt PF16910.5 CBK24162.2 - 1.1e-16 60.9 1.5 1e-12 48.0 0.1 4.2 3 1 0 3 3 3 2 Repeating coiled region of VPS13 VPS13_C PF16909.5 CBK24163.2 - 1.2e-58 197.8 1.5 1.3e-52 178.1 0.0 2.5 2 0 0 2 2 2 2 Vacuolar-sorting-associated 13 protein C-terminal DUF4708 PF15813.5 CBK24163.2 - 0.08 12.1 3.2 0.17 11.0 3.2 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4708) SR-25 PF10500.9 CBK24163.2 - 0.26 10.9 6.5 0.4 10.3 6.5 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein PRP1_N PF06424.12 CBK24163.2 - 0.27 11.6 0.8 9.5 6.6 0.3 2.4 2 0 0 2 2 2 0 PRP1 splicing factor, N-terminal AAA PF00004.29 CBK24165.2 - 1.2e-39 135.8 0.0 1.7e-39 135.3 0.0 1.2 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CBK24165.2 - 6.3e-09 35.5 0.0 1.2e-08 34.6 0.0 1.5 1 0 0 1 1 1 1 AAA+ lid domain Vps4_C PF09336.10 CBK24165.2 - 9.6e-07 28.7 0.0 2.1e-06 27.6 0.0 1.6 1 0 0 1 1 1 1 Vps4 C terminal oligomerisation domain RuvB_N PF05496.12 CBK24165.2 - 2.4e-06 27.4 0.0 4.1e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 CBK24165.2 - 4.2e-06 27.1 0.3 0.00013 22.3 0.3 2.7 1 1 1 2 2 2 1 AAA domain AAA_5 PF07728.14 CBK24165.2 - 1.7e-05 24.9 0.3 7.2e-05 22.8 0.3 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 CBK24165.2 - 3.6e-05 23.9 0.0 7.2e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_18 PF13238.6 CBK24165.2 - 5.9e-05 23.6 0.0 9.3e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 CBK24165.2 - 0.00017 22.0 0.1 0.0017 18.8 0.1 2.4 1 1 1 2 2 2 1 AAA ATPase domain AAA_25 PF13481.6 CBK24165.2 - 0.00017 21.2 0.5 0.022 14.3 0.2 2.4 1 1 0 2 2 2 1 AAA domain TIP49 PF06068.13 CBK24165.2 - 0.00021 20.6 0.0 0.00033 20.0 0.0 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_33 PF13671.6 CBK24165.2 - 0.00024 21.3 0.0 0.0011 19.2 0.0 2.1 1 1 1 2 2 2 1 AAA domain AAA_14 PF13173.6 CBK24165.2 - 0.00032 20.7 0.0 0.00064 19.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain TniB PF05621.11 CBK24165.2 - 0.00049 19.6 0.1 0.67 9.3 0.0 2.6 2 1 0 3 3 3 2 Bacterial TniB protein Mg_chelatase PF01078.21 CBK24165.2 - 0.00099 18.5 0.1 0.0024 17.3 0.1 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 CBK24165.2 - 0.0011 18.7 0.0 0.0021 17.8 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein DUF815 PF05673.13 CBK24165.2 - 0.0011 18.1 0.0 0.0019 17.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) Parvo_NS1 PF01057.17 CBK24165.2 - 0.0012 17.9 0.0 0.2 10.7 0.0 2.1 2 0 0 2 2 2 1 Parvovirus non-structural protein NS1 AAA_24 PF13479.6 CBK24165.2 - 0.0014 18.4 0.1 0.003 17.3 0.1 1.6 1 1 0 1 1 1 1 AAA domain NACHT PF05729.12 CBK24165.2 - 0.0033 17.4 0.1 0.14 12.1 0.1 2.3 1 1 0 1 1 1 1 NACHT domain RNA_helicase PF00910.22 CBK24165.2 - 0.0094 16.3 0.0 0.025 15.0 0.0 1.9 2 1 0 2 2 1 1 RNA helicase Sigma54_activat PF00158.26 CBK24165.2 - 0.021 14.6 0.0 0.27 10.9 0.0 2.2 2 0 0 2 2 2 0 Sigma-54 interaction domain Bac_DnaA PF00308.18 CBK24165.2 - 0.028 14.2 0.0 0.054 13.3 0.0 1.4 1 1 0 1 1 1 0 Bacterial dnaA protein TsaE PF02367.17 CBK24165.2 - 0.034 14.1 0.0 0.061 13.3 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_7 PF12775.7 CBK24165.2 - 0.034 13.6 0.1 0.071 12.6 0.1 1.6 1 1 0 1 1 1 0 P-loop containing dynein motor region Guanylate_kin PF00625.21 CBK24165.2 - 0.036 13.8 0.0 0.2 11.3 0.0 2.1 2 0 0 2 2 2 0 Guanylate kinase AAA_28 PF13521.6 CBK24165.2 - 0.06 13.6 0.0 0.086 13.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain PhoH PF02562.16 CBK24165.2 - 0.091 12.2 0.1 0.17 11.3 0.1 1.3 1 0 0 1 1 1 0 PhoH-like protein Zeta_toxin PF06414.12 CBK24165.2 - 0.16 11.2 0.0 0.37 10.0 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin ATPase PF06745.13 CBK24165.2 - 0.19 11.1 0.4 0.92 8.8 0.4 2.0 1 1 0 1 1 1 0 KaiC AAA_19 PF13245.6 CBK24165.2 - 0.21 11.9 0.2 0.43 10.9 0.1 1.6 1 1 0 1 1 1 0 AAA domain Phycoerythr_ab PF02972.14 CBK24166.2 - 0.093 12.6 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 Phycoerythrin, alpha/beta chain Sec16_C PF12931.7 CBK24168.2 - 4.9e-07 29.7 0.3 2.1e-06 27.7 0.3 1.9 1 1 0 1 1 1 1 Sec23-binding domain of Sec16 ANAPC4_WD40 PF12894.7 CBK24168.2 - 1.4e-05 25.3 7.8 0.36 11.2 0.6 5.4 3 2 2 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 CBK24168.2 - 0.00097 19.9 8.6 0.035 15.0 0.0 5.3 5 0 0 5 5 5 1 WD domain, G-beta repeat Frtz PF11768.8 CBK24168.2 - 0.011 14.0 0.1 0.019 13.3 0.1 1.2 1 0 0 1 1 1 0 WD repeat-containing and planar cell polarity effector protein Fritz DUF512 PF04459.12 CBK24168.2 - 0.081 12.2 0.0 0.22 10.8 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF512) MTS PF05175.14 CBK24169.2 - 3.1e-07 30.1 0.0 3.7e-07 29.8 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.6 CBK24169.2 - 0.0039 17.9 0.0 0.0045 17.7 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_24 PF13578.6 CBK24169.2 - 0.047 14.7 0.0 0.054 14.5 0.0 1.1 1 0 0 1 1 1 0 Methyltransferase domain PrmA PF06325.13 CBK24169.2 - 0.063 12.7 0.0 0.077 12.4 0.0 1.1 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) rRNA_methylase PF06962.12 CBK24169.2 - 0.093 12.7 0.0 0.13 12.2 0.0 1.4 1 1 0 1 1 1 0 Putative rRNA methylase Ribosomal_L3 PF00297.22 CBK24170.2 - 2.1e-19 69.8 4.5 2e-16 60.0 0.7 3.1 1 1 1 3 3 3 3 Ribosomal protein L3 DEAD PF00270.29 CBK24172.2 - 3.3e-40 137.7 0.3 5.2e-40 137.1 0.3 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CBK24172.2 - 2.2e-26 92.4 0.0 6.9e-25 87.5 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 CBK24172.2 - 2.8e-09 37.2 0.0 7.8e-09 35.8 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Astro_capsid_p PF12226.8 CBK24172.2 - 0.041 13.0 11.1 0.083 12.0 11.1 1.5 1 0 0 1 1 1 0 Turkey astrovirus capsid protein GRASP55_65 PF04495.14 CBK24172.2 - 0.16 12.3 0.3 0.43 10.9 0.1 1.8 2 0 0 2 2 2 0 GRASP55/65 PDZ-like domain Nop14 PF04147.12 CBK24172.2 - 0.38 8.9 11.7 0.76 7.9 11.7 1.4 1 0 0 1 1 1 0 Nop14-like family SAP PF02037.27 CBK24173.2 - 4.6e-07 29.4 0.0 7.3e-07 28.8 0.0 1.3 1 0 0 1 1 1 1 SAP domain Tho1_MOS11_C PF18592.1 CBK24173.2 - 0.015 15.1 0.2 0.03 14.1 0.2 1.5 1 0 0 1 1 1 0 Tho1/MOS11 C-terminal domain fn3 PF00041.21 CBK24174.2 - 5.4e-10 39.5 0.1 0.0004 20.7 0.0 4.8 5 0 0 5 5 5 3 Fibronectin type III domain Big_5 PF13205.6 CBK24174.2 - 1.2e-05 26.0 3.0 0.16 12.7 0.1 4.7 4 1 1 5 5 5 2 Bacterial Ig-like domain Pur_ac_phosph_N PF16656.5 CBK24174.2 - 1.3e-05 25.7 0.1 0.23 12.1 0.0 4.6 2 2 0 2 2 2 2 Purple acid Phosphatase, N-terminal domain Myco_19_kDa PF05481.12 CBK24174.2 - 0.14 12.5 0.2 0.76 10.1 0.0 2.3 3 0 0 3 3 3 0 Mycobacterium 19 kDa lipoprotein antigen Aa_trans PF01490.18 CBK24175.2 - 2.5e-58 197.7 29.8 3.2e-58 197.4 29.8 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein PT PF04886.12 CBK24175.2 - 0.43 10.2 6.1 0.95 9.1 6.1 1.5 1 0 0 1 1 1 0 PT repeat AAA PF00004.29 CBK24177.2 - 1.8e-08 34.9 0.0 4.6e-08 33.6 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Choline_kinase PF01633.20 CBK24178.2 - 6e-19 68.5 0.8 6e-19 68.5 0.8 1.9 2 1 0 2 2 2 1 Choline/ethanolamine kinase APH PF01636.23 CBK24178.2 - 3.6e-07 30.4 0.1 5.7e-07 29.7 0.1 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.20 CBK24178.2 - 0.064 12.6 0.1 0.1 11.9 0.1 1.3 1 0 0 1 1 1 0 Ecdysteroid kinase Pro_isomerase PF00160.21 CBK24179.2 - 1.6e-45 155.2 0.0 1.9e-45 155.0 0.0 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD CCT PF06203.14 CBK24180.2 - 0.024 14.7 1.2 0.082 13.0 1.2 1.8 1 1 0 1 1 1 0 CCT motif Synaptobrevin PF00957.21 CBK24181.2 - 5.9e-27 93.3 2.5 9.7e-27 92.6 2.5 1.4 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.6 CBK24181.2 - 4.2e-14 52.3 0.5 8.2e-14 51.4 0.5 1.5 1 0 0 1 1 1 1 Regulated-SNARE-like domain NAD_synthase PF02540.17 CBK24182.2 - 7.1e-31 107.2 0.0 1.4e-30 106.2 0.0 1.5 1 1 0 1 1 1 1 NAD synthase tRNA_Me_trans PF03054.16 CBK24182.2 - 0.1 11.3 0.1 0.15 10.9 0.1 1.2 1 0 0 1 1 1 0 tRNA methyl transferase PAPS_reduct PF01507.19 CBK24182.2 - 0.11 12.5 0.0 0.17 11.9 0.0 1.3 1 0 0 1 1 1 0 Phosphoadenosine phosphosulfate reductase family ATP_bind_3 PF01171.20 CBK24182.2 - 0.19 11.4 0.7 0.72 9.6 0.0 1.9 2 0 0 2 2 2 0 PP-loop family DNA_pol_B_2 PF03175.13 CBK24183.2 - 4.8e-05 22.4 3.9 0.088 11.7 1.0 2.1 2 0 0 2 2 2 2 DNA polymerase type B, organellar and viral MORN_2 PF07661.13 CBK24184.2 - 0.0046 17.0 9.4 0.71 10.3 0.3 4.5 4 0 0 4 4 4 2 MORN repeat variant DUF2207 PF09972.9 CBK24184.2 - 0.008 15.0 0.7 0.013 14.3 0.7 1.4 1 0 0 1 1 1 1 Predicted membrane protein (DUF2207) AC_N PF16214.5 CBK24184.2 - 0.009 15.2 4.0 0.013 14.7 4.0 1.1 1 0 0 1 1 1 1 Adenylyl cyclase N-terminal extracellular and transmembrane region GWT1 PF06423.12 CBK24184.2 - 0.012 15.8 0.6 0.018 15.2 0.6 1.3 1 0 0 1 1 1 0 GWT1 MRAP PF15183.6 CBK24184.2 - 6.1 6.9 7.2 0.55 10.2 1.2 2.4 2 1 1 3 3 3 0 Melanocortin-2 receptor accessory protein family Aminotran_5 PF00266.19 CBK24185.2 - 7.7e-88 294.9 0.0 1e-87 294.5 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 CBK24185.2 - 1.5e-10 40.8 0.0 2.5e-10 40.1 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 CBK24185.2 - 8.5e-09 35.1 0.0 1.2e-08 34.6 0.0 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.17 CBK24185.2 - 2e-07 30.6 0.1 3.2e-07 30.0 0.1 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Pyridoxal_deC PF00282.19 CBK24185.2 - 0.0019 17.0 0.0 0.0029 16.4 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Cys_Met_Meta_PP PF01053.20 CBK24185.2 - 0.0084 14.7 0.0 0.011 14.3 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme NIPSNAP PF07978.13 CBK24185.2 - 0.13 12.5 0.0 0.28 11.4 0.0 1.5 1 0 0 1 1 1 0 NIPSNAP Es2 PF09751.9 CBK24186.2 - 1.9e-39 136.6 18.4 1.9e-29 103.7 7.1 4.0 1 1 2 3 3 3 2 Nuclear protein Es2 BORA_N PF15280.6 CBK24186.2 - 0.014 15.0 0.3 0.029 14.0 0.3 1.5 1 0 0 1 1 1 0 Protein aurora borealis N-terminus CTD PF12815.7 CBK24186.2 - 0.96 10.1 6.6 29 5.3 0.1 3.3 2 1 0 2 2 2 0 Spt5 C-terminal nonapeptide repeat binding Spt4 Actin PF00022.19 CBK24188.2 - 1.2e-134 449.0 0.0 4.3e-134 447.1 0.0 1.7 1 1 0 1 1 1 1 Actin Peptidase_M18 PF02127.15 CBK24189.2 - 2.7e-146 487.7 0.0 3.1e-146 487.5 0.0 1.0 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Peptidase_M42 PF05343.14 CBK24189.2 - 1.2e-08 34.3 0.6 2.6e-05 23.4 0.1 2.9 3 0 0 3 3 3 2 M42 glutamyl aminopeptidase Ribosomal_S9 PF00380.19 CBK24190.2 - 5.1e-40 136.8 1.0 7.5e-40 136.2 1.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S9/S16 DUF4692 PF15763.5 CBK24190.2 - 0.043 14.3 0.5 0.043 14.3 0.5 2.0 2 0 0 2 2 2 0 Regulator of human erythroid cell expansion (RHEX) Big_5 PF13205.6 CBK24191.2 - 8.4e-07 29.7 0.6 0.05 14.3 0.0 3.2 2 1 1 3 3 3 3 Bacterial Ig-like domain fn3 PF00041.21 CBK24192.2 - 2.6e-07 30.9 0.0 3.8 7.9 0.0 5.0 5 0 0 5 5 5 3 Fibronectin type III domain Pur_ac_phosph_N PF16656.5 CBK24192.2 - 6.4e-06 26.7 0.1 0.053 14.1 0.0 4.4 4 1 0 4 4 4 1 Purple acid Phosphatase, N-terminal domain Myco_19_kDa PF05481.12 CBK24192.2 - 0.11 12.8 0.0 0.24 11.7 0.0 1.6 1 0 0 1 1 1 0 Mycobacterium 19 kDa lipoprotein antigen SAP PF02037.27 CBK24193.2 - 3e-07 30.0 0.0 3.9e-07 29.7 0.0 1.1 1 0 0 1 1 1 1 SAP domain Trypan_PARP PF05887.11 CBK24194.2 - 0.00057 19.9 8.0 0.00078 19.4 8.0 1.2 1 0 0 1 1 1 1 Procyclic acidic repetitive protein (PARP) TraF PF13728.6 CBK24194.2 - 9.9 5.9 7.8 15 5.3 7.8 1.2 1 0 0 1 1 1 0 F plasmid transfer operon protein Fer2_3 PF13085.6 CBK24195.2 - 2.6e-33 114.3 0.1 4.6e-33 113.5 0.1 1.4 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer4_8 PF13183.6 CBK24195.2 - 1.8e-08 34.7 7.3 1.8e-08 34.7 7.3 2.4 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_17 PF13534.6 CBK24195.2 - 2e-08 34.7 6.5 2e-08 34.7 6.5 2.1 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_10 PF13237.6 CBK24195.2 - 2.6e-07 30.6 3.4 2.6e-07 30.6 3.4 2.1 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer2 PF00111.27 CBK24195.2 - 0.0004 20.3 0.4 0.0004 20.3 0.4 2.0 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fer4_7 PF12838.7 CBK24195.2 - 0.0033 18.0 4.9 0.0033 18.0 4.9 2.8 2 2 0 2 2 2 1 4Fe-4S dicluster domain Fer4_9 PF13187.6 CBK24195.2 - 0.027 14.6 7.9 0.027 14.6 7.9 2.5 2 1 0 2 2 2 0 4Fe-4S dicluster domain Herpes_UL51 PF04540.13 CBK24195.2 - 0.12 12.1 0.0 0.2 11.4 0.0 1.3 1 0 0 1 1 1 0 Herpesvirus UL51 protein CBF PF03914.17 CBK24196.2 - 3e-15 56.7 0.3 1.4e-14 54.5 0.4 2.1 2 0 0 2 2 2 1 CBF/Mak21 family Trypan_glycop PF00913.19 CBK24196.2 - 0.059 12.6 0.1 0.081 12.2 0.1 1.1 1 0 0 1 1 1 0 Trypanosome variant surface glycoprotein (A-type) RNA_pol_3_Rpc31 PF11705.8 CBK24196.2 - 1.7 8.8 6.9 2.7 8.2 6.9 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 DUF1087 PF06465.13 CBK24196.2 - 3.4 7.8 8.7 0.9 9.6 0.1 3.3 2 1 2 4 4 4 0 Domain of Unknown Function (DUF1087) XRN_M PF17846.1 CBK24197.2 - 4.3e-102 342.3 0.0 5.1e-100 335.5 0.0 2.2 1 1 0 1 1 1 1 Xrn1 helical domain XRN_N PF03159.18 CBK24197.2 - 3.4e-95 318.1 1.0 7.3e-95 317.0 0.0 1.9 2 0 0 2 2 2 1 XRN 5'-3' exonuclease N-terminus PI3_PI4_kinase PF00454.27 CBK24197.2 - 5.7e-23 82.0 0.0 1.2e-20 74.4 0.0 2.3 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase zf-CCHC_3 PF13917.6 CBK24197.2 - 0.11 12.5 0.6 0.26 11.3 0.6 1.5 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC PF00098.23 CBK24197.2 - 0.14 12.3 0.7 0.33 11.1 0.7 1.6 1 0 0 1 1 1 0 Zinc knuckle ENTH PF01417.20 CBK24198.2 - 7.8e-32 109.9 0.1 1.4e-31 109.1 0.1 1.4 1 0 0 1 1 1 1 ENTH domain ANTH PF07651.16 CBK24198.2 - 0.0027 16.8 0.0 0.0056 15.7 0.0 1.5 1 0 0 1 1 1 1 ANTH domain RNase_PH PF01138.21 CBK24200.2 - 3.6e-26 92.2 0.0 7.6e-26 91.2 0.0 1.5 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 Mre11_DNA_bind PF04152.14 CBK24200.2 - 6.7e-22 78.6 0.0 1.4e-21 77.6 0.0 1.5 1 0 0 1 1 1 1 Mre11 DNA-binding presumed domain Metallophos PF00149.28 CBK24200.2 - 2.3e-10 41.3 0.2 4.4e-10 40.4 0.2 1.4 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 CBK24200.2 - 0.054 13.7 0.0 0.47 10.6 0.0 2.4 1 1 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain RNase_PH_C PF03725.15 CBK24200.2 - 0.12 12.5 0.0 0.25 11.4 0.0 1.6 1 0 0 1 1 1 0 3' exoribonuclease family, domain 2 Pkinase PF00069.25 CBK24202.2 - 2.1e-39 135.5 0.0 2.5e-39 135.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBK24202.2 - 5.5e-21 75.0 0.0 6.2e-21 74.9 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CBK24202.2 - 8.3e-06 25.3 0.0 9.3e-06 25.2 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 CBK24202.2 - 0.0028 16.7 0.1 0.0031 16.5 0.1 1.1 1 0 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 CBK24202.2 - 0.043 12.6 0.0 0.049 12.4 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase Kdo PF06293.14 CBK24202.2 - 0.06 12.7 1.0 0.094 12.1 1.0 1.3 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CBK24202.2 - 0.1 12.5 0.0 0.13 12.1 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family Big_5 PF13205.6 CBK24203.2 - 1.8e-16 60.8 4.9 2.1e-08 34.8 0.1 5.4 6 0 0 6 6 6 3 Bacterial Ig-like domain fn3 PF00041.21 CBK24203.2 - 1e-08 35.4 1.7 0.03 14.7 0.0 5.8 5 0 0 5 5 5 1 Fibronectin type III domain CopC PF04234.12 CBK24203.2 - 1.5e-05 25.9 1.8 0.86 10.7 0.0 4.2 3 1 0 3 3 3 2 CopC domain Pur_ac_phosph_N PF16656.5 CBK24203.2 - 0.00052 20.5 1.3 20 5.8 0.0 4.8 3 1 1 4 4 4 2 Purple acid Phosphatase, N-terminal domain DUF2369 PF10179.9 CBK24203.2 - 0.0077 16.6 1.0 6.9 7.1 0.0 4.0 4 0 0 4 4 4 1 Uncharacterised conserved protein (DUF2369) FixH PF05751.11 CBK24203.2 - 0.088 12.8 0.2 0.38 10.8 0.1 2.0 2 0 0 2 2 2 0 FixH MMR_HSR1 PF01926.23 CBK24204.2 - 8e-42 141.9 0.1 7.5e-22 77.6 0.0 2.4 2 0 0 2 2 2 2 50S ribosome-binding GTPase KH_dom-like PF14714.6 CBK24204.2 - 1.4e-27 95.8 0.2 3.5e-27 94.5 0.1 1.8 2 0 0 2 2 1 1 KH-domain-like of EngA bacterial GTPase enzymes, C-terminal FeoB_N PF02421.18 CBK24204.2 - 6.1e-21 74.6 0.0 2e-10 40.4 0.0 2.3 2 0 0 2 2 2 2 Ferrous iron transport protein B AIG1 PF04548.16 CBK24204.2 - 4.7e-14 52.2 0.0 2.3e-06 27.1 0.0 2.5 2 0 0 2 2 2 2 AIG1 family Dynamin_N PF00350.23 CBK24204.2 - 1.2e-12 48.2 0.6 0.0079 16.3 0.0 4.4 3 1 1 4 4 4 3 Dynamin family RsgA_GTPase PF03193.16 CBK24204.2 - 6.5e-10 39.2 0.2 0.0021 18.0 0.1 3.2 3 0 0 3 3 3 2 RsgA GTPase GTP_EFTU PF00009.27 CBK24204.2 - 1.1e-07 31.5 1.3 0.0089 15.6 0.2 4.4 2 2 0 2 2 2 2 Elongation factor Tu GTP binding domain ABC_tran PF00005.27 CBK24204.2 - 3e-07 31.0 0.1 0.033 14.7 0.0 2.6 2 1 0 2 2 2 2 ABC transporter SRPRB PF09439.10 CBK24204.2 - 2.1e-05 24.1 0.1 0.089 12.2 0.0 2.4 2 0 0 2 2 2 2 Signal recognition particle receptor beta subunit Septin PF00735.18 CBK24204.2 - 0.0006 19.2 1.8 1.1 8.5 0.1 3.3 2 1 1 3 3 3 2 Septin Arf PF00025.21 CBK24204.2 - 0.00069 19.1 0.4 0.13 11.7 0.1 2.7 3 0 0 3 3 3 1 ADP-ribosylation factor family G-alpha PF00503.20 CBK24204.2 - 0.00084 18.6 0.1 0.47 9.6 0.0 3.2 3 0 0 3 3 3 1 G-protein alpha subunit FtsK_SpoIIIE PF01580.18 CBK24204.2 - 0.00095 18.6 0.3 0.72 9.2 0.1 3.2 2 1 1 3 3 3 1 FtsK/SpoIIIE family Roc PF08477.13 CBK24204.2 - 0.00099 19.3 0.1 0.29 11.4 0.0 2.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase AAA_29 PF13555.6 CBK24204.2 - 0.0015 18.2 0.0 1.7 8.5 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain Ras PF00071.22 CBK24204.2 - 0.0034 17.0 0.0 1.8 8.1 0.0 2.6 3 0 0 3 3 2 1 Ras family AAA_24 PF13479.6 CBK24204.2 - 0.0088 15.8 0.0 3.3 7.4 0.0 2.9 3 0 0 3 3 2 1 AAA domain AAA_22 PF13401.6 CBK24204.2 - 0.015 15.6 0.0 11 6.3 0.0 2.8 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.22 CBK24204.2 - 0.048 12.8 0.0 5.6 6.1 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain TniB PF05621.11 CBK24204.2 - 0.06 12.7 0.1 1.5 8.2 0.0 2.5 3 0 0 3 3 3 0 Bacterial TniB protein AAA_14 PF13173.6 CBK24204.2 - 0.061 13.4 0.2 3.8 7.6 0.0 2.8 2 1 0 2 2 2 0 AAA domain AAA_18 PF13238.6 CBK24204.2 - 0.068 13.7 0.1 8.6 6.9 0.0 2.6 2 0 0 2 2 2 0 AAA domain Gtr1_RagA PF04670.12 CBK24204.2 - 0.13 11.6 0.0 0.51 9.6 0.0 1.9 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region AAA_33 PF13671.6 CBK24204.2 - 0.13 12.4 0.0 9.2 6.4 0.0 2.6 2 0 0 2 2 2 0 AAA domain MobB PF03205.14 CBK24204.2 - 0.14 12.0 0.3 26 4.7 0.0 2.6 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B cobW PF02492.19 CBK24204.2 - 0.18 11.4 2.7 9.3 5.8 0.2 3.3 2 2 1 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain Big_5 PF13205.6 CBK24206.2 - 3.7e-25 88.7 0.6 1.8e-09 38.2 0.0 3.2 3 0 0 3 3 3 3 Bacterial Ig-like domain MFMR_assoc PF16596.5 CBK24207.2 - 0.46 10.9 16.4 0.7 10.4 16.4 1.2 1 0 0 1 1 1 0 Disordered region downstream of MFMR GSIII_N PF12437.8 CBK24208.2 - 3e-62 209.0 0.0 8.7e-62 207.5 0.0 1.8 2 0 0 2 2 2 1 Glutamine synthetase type III N terminal Gln-synt_C-ter PF18318.1 CBK24208.2 - 1.1e-34 118.8 0.0 3.4e-34 117.2 0.0 1.8 2 0 0 2 2 2 1 Glutamine synthetase C-terminal domain Gln-synt_C PF00120.24 CBK24208.2 - 2.5e-20 72.8 0.0 4.5e-20 71.9 0.0 1.3 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain La PF05383.17 CBK24209.2 - 1.2e-21 76.4 0.1 2.7e-21 75.4 0.1 1.6 1 0 0 1 1 1 1 La domain RRM_1 PF00076.22 CBK24209.2 - 1.1e-13 50.7 0.3 2e-05 24.3 0.1 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 CBK24209.2 - 1.4e-13 50.8 5.9 3.5e-10 39.8 1.7 2.4 2 0 0 2 2 2 2 RNA binding motif PTS_2-RNA PF01885.16 CBK24209.2 - 0.005 16.9 0.1 0.0082 16.2 0.0 1.6 1 1 0 1 1 1 1 RNA 2'-phosphotransferase, Tpt1 / KptA family ETC_C1_NDUFA4 PF04800.12 CBK24209.2 - 0.044 14.0 0.9 0.39 11.0 0.3 2.5 2 1 1 3 3 3 0 ETC complex I subunit conserved region Lactamase_B_2 PF12706.7 CBK24210.2 - 3.3e-10 39.8 0.3 0.00089 18.8 0.0 3.1 2 1 0 2 2 2 2 Beta-lactamase superfamily domain Lactamase_B PF00753.27 CBK24210.2 - 0.00018 21.6 0.0 0.0003 20.9 0.0 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Thioredoxin PF00085.20 CBK24211.2 - 1.4e-09 37.9 0.0 2.3e-09 37.2 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin TraF PF13728.6 CBK24211.2 - 0.00031 20.6 0.0 0.00031 20.6 0.0 1.6 2 0 0 2 2 2 1 F plasmid transfer operon protein Thioredoxin_2 PF13098.6 CBK24211.2 - 0.0013 19.2 0.1 0.0029 18.0 0.1 1.6 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_4 PF13462.6 CBK24211.2 - 0.0043 17.2 0.1 0.0043 17.2 0.1 1.7 2 0 0 2 2 2 1 Thioredoxin DUF393 PF04134.12 CBK24211.2 - 0.019 16.3 0.1 0.044 15.1 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function, DUF393 Acetyltransf_10 PF13673.7 CBK24212.2 - 5.9e-07 29.5 0.0 6.6e-07 29.3 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 CBK24212.2 - 5.7e-06 26.7 0.1 7e-06 26.4 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 CBK24212.2 - 0.0013 19.0 0.1 0.0016 18.6 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family NodZ PF05830.11 CBK24213.2 - 4.2e-10 39.0 0.0 6.6e-10 38.3 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein Z (NodZ) O-FucT PF10250.9 CBK24213.2 - 8.8e-05 22.3 0.1 0.00013 21.8 0.1 1.3 1 0 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase Glyco_hydro_47 PF01532.20 CBK24214.2 - 1.3e-145 485.8 0.5 1.6e-145 485.6 0.5 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 GlcNAc_2-epim PF07221.11 CBK24214.2 - 0.0014 17.9 0.0 1.3 8.2 0.0 2.4 2 0 0 2 2 2 2 N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase) AAA_12 PF13087.6 CBK24215.2 - 3.9e-61 206.2 0.0 7.8e-61 205.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain UPF1_Zn_bind PF09416.10 CBK24215.2 - 4e-45 153.5 6.9 4.2e-44 150.2 5.6 2.7 2 0 0 2 2 2 1 RNA helicase (UPF2 interacting domain) AAA_11 PF13086.6 CBK24215.2 - 2.5e-44 152.0 9.3 3.4e-24 86.0 0.1 2.8 3 0 0 3 3 2 2 AAA domain AAA_30 PF13604.6 CBK24215.2 - 4.1e-12 46.2 0.0 2.9e-11 43.4 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 CBK24215.2 - 3.6e-11 43.6 0.0 1.8e-10 41.4 0.0 2.1 2 1 0 2 2 2 1 AAA domain DUF5599 PF18141.1 CBK24215.2 - 2.5e-10 40.4 0.0 5.1e-10 39.5 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF5599) ResIII PF04851.15 CBK24215.2 - 4.4e-06 26.8 0.0 1.5e-05 25.1 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Viral_helicase1 PF01443.18 CBK24215.2 - 1.9e-05 24.5 0.0 0.34 10.6 0.0 3.2 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase DUF2075 PF09848.9 CBK24215.2 - 5.3e-05 22.6 0.0 0.0006 19.2 0.0 2.5 2 1 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) PIF1 PF05970.14 CBK24215.2 - 0.00014 21.2 0.0 0.044 13.0 0.0 2.3 2 0 0 2 2 2 1 PIF1-like helicase DEAD PF00270.29 CBK24215.2 - 0.00095 19.0 0.0 0.0025 17.6 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase UvrD-helicase PF00580.21 CBK24215.2 - 0.0011 18.6 0.0 0.086 12.3 0.0 2.6 1 1 1 2 2 2 1 UvrD/REP helicase N-terminal domain Helicase_RecD PF05127.14 CBK24215.2 - 0.0059 16.5 0.0 0.0059 16.5 0.0 1.8 2 0 0 2 2 1 1 Helicase ATPase PF06745.13 CBK24215.2 - 0.0061 15.9 0.0 0.013 14.8 0.0 1.5 1 0 0 1 1 1 1 KaiC Sigma54_activat PF00158.26 CBK24215.2 - 0.0068 16.1 0.0 0.5 10.1 0.0 2.5 2 0 0 2 2 2 1 Sigma-54 interaction domain PhoH PF02562.16 CBK24215.2 - 0.017 14.5 0.1 0.059 12.8 0.0 1.8 2 0 0 2 2 2 0 PhoH-like protein AAA_22 PF13401.6 CBK24215.2 - 0.021 15.1 0.0 1.1 9.5 0.0 3.1 3 0 0 3 3 3 0 AAA domain AAA_16 PF13191.6 CBK24215.2 - 0.03 14.7 0.0 0.15 12.4 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain AAA_26 PF13500.6 CBK24215.2 - 0.058 13.2 0.0 0.17 11.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain DnaB_C PF03796.15 CBK24215.2 - 0.084 12.2 0.0 0.16 11.3 0.0 1.4 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain T2SSE PF00437.20 CBK24215.2 - 0.087 11.9 0.0 0.15 11.1 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein UvrD_C_2 PF13538.6 CBK24215.2 - 0.13 12.1 0.0 1 9.2 0.0 2.4 2 0 0 2 2 2 0 UvrD-like helicase C-terminal domain AAA PF00004.29 CBK24215.2 - 0.16 12.4 0.0 0.71 10.3 0.0 2.2 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.21 CBK24215.2 - 0.16 11.3 0.0 0.35 10.2 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI RuvB_N PF05496.12 CBK24215.2 - 0.17 11.6 0.0 2.5 7.8 0.0 2.3 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain Prok-RING_2 PF14445.6 CBK24215.2 - 1.1 9.5 7.7 3.7 7.8 7.7 1.9 1 0 0 1 1 1 0 Prokaryotic RING finger family 2 Syja_N PF02383.18 CBK24216.2 - 1.5e-06 27.8 0.3 2.6e-06 27.0 0.1 1.5 2 0 0 2 2 2 1 SacI homology domain Syja_N PF02383.18 CBK24217.2 - 6e-50 170.4 0.0 7.9e-50 170.0 0.0 1.2 1 0 0 1 1 1 1 SacI homology domain zf-ribbon_3 PF13248.6 CBK24217.2 - 0.17 11.4 3.4 0.48 9.9 3.4 1.8 1 0 0 1 1 1 0 zinc-ribbon domain RIC1 PF07064.13 CBK24218.2 - 1.9e-13 50.5 0.8 1.9e-13 50.5 0.8 1.8 2 0 0 2 2 2 1 RIC1 Ras PF00071.22 CBK24219.2 - 1.6e-57 193.6 1.5 2.3e-57 193.1 1.5 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CBK24219.2 - 1.6e-32 112.2 0.3 3.1e-32 111.3 0.3 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CBK24219.2 - 6.4e-14 51.8 0.1 9.3e-14 51.3 0.1 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 CBK24219.2 - 6.4e-05 22.6 0.4 0.00012 21.7 0.4 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 CBK24219.2 - 0.0006 19.2 0.2 0.00093 18.6 0.2 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 CBK24219.2 - 0.0013 18.6 0.0 1.4 8.8 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase VirE PF05272.11 CBK24219.2 - 0.0024 17.6 0.0 0.0052 16.5 0.0 1.5 1 1 0 1 1 1 1 Virulence-associated protein E AAA_22 PF13401.6 CBK24219.2 - 0.0062 16.8 0.1 0.023 14.9 0.1 2.0 1 1 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.23 CBK24219.2 - 0.0063 16.6 0.2 0.013 15.5 0.1 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 CBK24219.2 - 0.0065 15.9 0.0 0.0094 15.4 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit TniB PF05621.11 CBK24219.2 - 0.052 12.9 0.0 0.086 12.2 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein FeoB_N PF02421.18 CBK24219.2 - 0.069 12.7 0.2 6.6 6.3 0.1 2.1 2 0 0 2 2 2 0 Ferrous iron transport protein B Pho88 PF10032.9 CBK24219.2 - 0.087 12.1 0.0 0.14 11.4 0.0 1.3 1 0 0 1 1 1 0 Phosphate transport (Pho88) AAA_7 PF12775.7 CBK24219.2 - 0.12 11.8 0.0 0.22 11.0 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region Proteasome PF00227.26 CBK24220.2 - 6.2e-30 104.1 0.0 7.3e-30 103.9 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Calsequestrin PF01216.17 CBK24220.2 - 0.02 13.9 0.0 0.025 13.6 0.0 1.1 1 0 0 1 1 1 0 Calsequestrin ATP-grasp_2 PF08442.10 CBK24221.2 - 1.1e-67 227.5 0.0 1.7e-67 226.9 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain Ligase_CoA PF00549.19 CBK24221.2 - 7.7e-24 84.3 1.3 1.2e-23 83.6 1.3 1.3 1 0 0 1 1 1 1 CoA-ligase Citrate_bind PF16114.5 CBK24221.2 - 0.02 14.4 0.2 0.038 13.5 0.2 1.4 1 0 0 1 1 1 0 ATP citrate lyase citrate-binding Succ_CoA_lig PF13607.6 CBK24221.2 - 0.043 13.6 0.2 0.083 12.7 0.2 1.5 1 0 0 1 1 1 0 Succinyl-CoA ligase like flavodoxin domain LPD29 PF18847.1 CBK24221.2 - 0.057 14.4 0.0 1.4 9.9 0.0 2.4 2 0 0 2 2 2 0 Large polyvalent protein associated domain 29 E2F_TDP PF02319.20 CBK24222.2 - 2.2e-06 27.6 0.1 4.8e-06 26.5 0.1 1.5 1 0 0 1 1 1 1 E2F/DP family winged-helix DNA-binding domain PspA_IM30 PF04012.12 CBK24222.2 - 6.8e-05 22.6 0.4 9.8e-05 22.0 0.4 1.1 1 0 0 1 1 1 1 PspA/IM30 family CAMSAP_CC1 PF17095.5 CBK24222.2 - 0.041 13.7 4.3 0.092 12.6 4.3 1.6 1 0 0 1 1 1 0 Spectrin-binding region of Ca2+-Calmodulin Lipoprotein_20 PF13942.6 CBK24222.2 - 1.4 8.8 6.0 1.3 8.9 4.1 1.8 2 0 0 2 2 2 0 YfhG lipoprotein Ras PF00071.22 CBK24223.2 - 2.4e-42 144.3 0.4 2.9e-42 144.0 0.4 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CBK24223.2 - 1.2e-32 112.7 0.0 1.9e-32 112.0 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CBK24223.2 - 4.6e-12 45.7 0.0 7e-12 45.1 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 CBK24223.2 - 5.1e-07 29.3 0.1 6.4e-07 29.0 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 CBK24223.2 - 4.6e-05 23.5 0.0 6.9e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 CBK24223.2 - 0.00017 21.5 0.2 0.2 11.5 0.1 2.3 1 1 0 2 2 2 2 RsgA GTPase FeoB_N PF02421.18 CBK24223.2 - 0.0055 16.2 0.2 0.043 13.4 0.2 2.0 1 1 0 1 1 1 1 Ferrous iron transport protein B G-alpha PF00503.20 CBK24223.2 - 0.0057 15.9 0.0 0.17 11.0 0.0 2.1 2 0 0 2 2 2 1 G-protein alpha subunit AAA_16 PF13191.6 CBK24223.2 - 0.046 14.1 0.1 0.071 13.5 0.1 1.4 1 1 0 1 1 1 0 AAA ATPase domain DUF815 PF05673.13 CBK24223.2 - 0.046 12.9 0.0 0.092 11.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) TniB PF05621.11 CBK24223.2 - 0.058 12.8 0.0 0.18 11.2 0.0 1.7 2 0 0 2 2 2 0 Bacterial TniB protein AAA_14 PF13173.6 CBK24223.2 - 0.067 13.2 0.0 0.22 11.6 0.0 1.9 1 1 0 1 1 1 0 AAA domain She9_MDM33 PF05546.11 CBK24224.2 - 8e-18 65.0 13.7 9.2e-18 64.8 13.7 1.1 1 0 0 1 1 1 1 She9 / Mdm33 family UPF0242 PF06785.11 CBK24224.2 - 0.12 12.5 11.7 0.18 11.9 11.7 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Adeno_E4 PF05385.11 CBK24224.2 - 0.18 11.9 2.2 0.34 11.0 2.2 1.4 1 0 0 1 1 1 0 Mastadenovirus early E4 13 kDa protein TMF_TATA_bd PF12325.8 CBK24224.2 - 0.2 11.9 10.0 0.35 11.1 10.0 1.5 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding DUF5344 PF17279.2 CBK24224.2 - 0.29 11.7 6.0 0.26 11.9 1.8 2.4 1 1 1 2 2 2 0 Family of unknown function (DUF5344) DcrB PF08786.11 CBK24224.2 - 0.55 10.3 4.0 2.6 8.1 0.1 2.6 2 1 0 2 2 2 0 DcrB DUF2358 PF10184.9 CBK24224.2 - 0.56 10.5 5.0 0.22 11.8 2.3 1.6 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2358) OmpH PF03938.14 CBK24224.2 - 3 8.2 18.3 9.4 6.6 18.3 1.8 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) CENP-H PF05837.12 CBK24224.2 - 4.3 7.8 10.2 4 7.9 8.4 1.8 1 1 0 1 1 1 0 Centromere protein H (CENP-H) CREPT PF16566.5 CBK24224.2 - 4.3 7.5 11.7 0.25 11.5 3.8 2.1 1 1 0 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour PH PF00169.29 CBK24225.2 - 5.7e-08 33.2 0.0 8.5e-08 32.7 0.0 1.3 1 0 0 1 1 1 1 PH domain zf-RING_11 PF17123.5 CBK24226.2 - 7.5e-12 44.8 8.0 1.1e-11 44.2 7.3 1.7 2 0 0 2 2 2 1 RING-like zinc finger zf-RING_2 PF13639.6 CBK24226.2 - 2.3e-11 43.8 2.6 3.2e-11 43.4 2.6 1.2 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 CBK24226.2 - 1.4e-07 31.2 2.5 2.1e-07 30.7 2.5 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CBK24226.2 - 1.7e-07 31.2 2.1 2.5e-07 30.6 2.1 1.3 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 CBK24226.2 - 4.3e-07 29.7 1.8 7.1e-07 29.0 1.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CBK24226.2 - 1e-05 25.4 2.3 1.5e-05 24.8 2.3 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.7 CBK24226.2 - 2.5e-05 24.5 3.5 0.00011 22.4 3.5 1.9 1 1 0 1 1 1 1 RING-H2 zinc finger domain Zn_ribbon_17 PF17120.5 CBK24226.2 - 0.00045 19.8 1.2 0.0007 19.2 1.2 1.3 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-ANAPC11 PF12861.7 CBK24226.2 - 0.0018 18.3 1.8 0.009 16.0 1.8 2.1 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger FANCL_C PF11793.8 CBK24226.2 - 0.0027 17.9 1.6 0.0055 16.9 1.6 1.5 1 1 0 1 1 1 1 FANCL C-terminal domain zf-C3HC4_3 PF13920.6 CBK24226.2 - 0.0041 17.0 1.9 0.0054 16.6 1.9 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Vps39_2 PF10367.9 CBK24226.2 - 0.0068 16.8 2.0 0.01 16.2 2.0 1.3 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 PIP49_N PF14875.6 CBK24226.2 - 0.0092 15.9 0.5 0.0096 15.8 0.5 1.1 1 0 0 1 1 1 1 N-term cysteine-rich ER, FAM69 zf-C3HC4_4 PF15227.6 CBK24226.2 - 0.029 14.5 4.2 0.36 11.0 4.3 2.1 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING Zf_RING PF16744.5 CBK24226.2 - 0.036 14.2 0.6 0.06 13.5 0.6 1.3 1 0 0 1 1 1 0 KIAA1045 RING finger DUF3918 PF13056.6 CBK24226.2 - 0.042 13.5 1.3 0.058 13.0 1.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3918) DUF2175 PF09943.9 CBK24226.2 - 0.081 13.2 1.9 0.2 11.9 1.6 1.8 2 1 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2175) Prok-RING_4 PF14447.6 CBK24226.2 - 0.14 12.1 2.8 0.23 11.4 2.8 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 Ribosomal_S3Ae PF01015.18 CBK24227.2 - 2.2e-84 282.0 2.9 2.9e-84 281.7 2.9 1.1 1 0 0 1 1 1 1 Ribosomal S3Ae family SUI1 PF01253.22 CBK24227.2 - 0.0014 19.1 0.4 0.006 17.1 0.3 2.2 1 1 1 2 2 2 1 Translation initiation factor SUI1 Abhydro_lipase PF04083.16 CBK24227.2 - 0.029 13.9 0.6 0.072 12.7 0.0 1.9 3 0 0 3 3 3 0 Partial alpha/beta-hydrolase lipase region DUF3395 PF11875.8 CBK24227.2 - 0.056 13.3 0.0 0.21 11.5 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3395) Collagen PF01391.18 CBK24228.2 - 0.33 10.8 6.5 0.4 10.5 4.9 1.9 2 0 0 2 2 2 0 Collagen triple helix repeat (20 copies) PRKCSH PF07915.13 CBK24230.2 - 8.9e-06 26.6 1.9 8.9e-06 26.6 1.9 1.8 2 0 0 2 2 2 1 Glucosidase II beta subunit-like protein Yippee-Mis18 PF03226.14 CBK24230.2 - 3.9e-05 23.8 0.1 7.7e-05 22.9 0.1 1.5 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly PRKCSH_1 PF13015.6 CBK24230.2 - 0.00065 19.4 0.0 0.0011 18.6 0.0 1.4 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein DUF2757 PF10955.8 CBK24230.2 - 0.0026 18.0 0.4 2.4 8.5 0.0 2.6 2 0 0 2 2 2 2 Protein of unknown function (DUF2757) Imm44 PF15571.6 CBK24230.2 - 0.017 15.4 0.1 0.24 11.7 0.0 2.7 2 1 1 3 3 3 0 Immunity protein 44 zf-LITAF-like PF10601.9 CBK24230.2 - 0.041 14.2 9.0 0.047 14.0 1.4 3.1 3 0 0 3 3 3 0 LITAF-like zinc ribbon domain CMS1 PF14617.6 CBK24231.2 - 2.4e-22 79.5 0.4 2.4e-22 79.5 0.4 2.1 2 0 0 2 2 2 1 U3-containing 90S pre-ribosomal complex subunit DEAD PF00270.29 CBK24231.2 - 0.00041 20.2 0.0 0.00068 19.5 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase BRCT_2 PF16589.5 CBK24232.2 - 7e-14 52.0 0.0 1.2e-13 51.2 0.0 1.4 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 CBK24232.2 - 7.3e-09 35.9 0.0 1.6e-08 34.8 0.0 1.6 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain DNA_ligase_A_M PF01068.21 CBK24233.2 - 7.7e-66 221.6 0.1 1.3e-65 220.9 0.1 1.4 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 CBK24233.2 - 1.4e-41 142.7 0.0 2.4e-41 141.9 0.0 1.4 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.15 CBK24233.2 - 2.9e-21 75.9 0.0 5.3e-21 75.1 0.0 1.4 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region DNA_ligase_OB_2 PF14743.6 CBK24233.2 - 0.026 14.5 0.7 11 6.1 0.1 2.6 2 0 0 2 2 2 0 DNA ligase OB-like domain Peptidase_A21 PF03566.13 CBK24234.2 - 2.3 6.4 4.8 2.7 6.1 4.8 1.1 1 0 0 1 1 1 0 Peptidase family A21 Rrn6 PF10214.9 CBK24234.2 - 2.3 6.6 4.1 2.8 6.3 4.1 1.0 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor Shisa PF13908.6 CBK24235.2 - 1.9e-06 28.2 1.9 4.9e-06 26.9 1.9 1.6 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator He_PIG PF05345.12 CBK24235.2 - 2.1e-06 27.8 6.5 8.2e-06 25.9 6.5 2.0 1 0 0 1 1 1 1 Putative Ig domain OAD_gamma PF04277.13 CBK24235.2 - 0.0029 18.1 0.3 0.0065 17.0 0.3 1.6 1 0 0 1 1 1 1 Oxaloacetate decarboxylase, gamma chain TMEM154 PF15102.6 CBK24235.2 - 0.011 15.6 2.1 0.021 14.7 2.1 1.4 1 0 0 1 1 1 0 TMEM154 protein family EphA2_TM PF14575.6 CBK24235.2 - 0.016 16.1 2.6 0.039 14.8 2.6 1.6 1 1 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Orf78 PF06024.12 CBK24235.2 - 0.02 15.2 0.9 0.039 14.3 0.9 1.4 1 0 0 1 1 1 0 Orf78 (ac78) Trypan_PARP PF05887.11 CBK24235.2 - 0.026 14.5 0.4 0.049 13.6 0.4 1.4 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) DUF5305 PF17231.2 CBK24235.2 - 0.027 13.9 2.6 0.045 13.2 2.6 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5305) RIFIN PF02009.16 CBK24235.2 - 0.035 14.0 2.5 0.062 13.2 2.5 1.3 1 0 0 1 1 1 0 Rifin F5_F8_type_C PF00754.25 CBK24235.2 - 0.064 13.4 0.0 0.064 13.4 0.0 2.6 3 0 0 3 3 3 0 F5/8 type C domain OSTbeta PF15048.6 CBK24235.2 - 0.1 12.7 0.2 0.2 11.8 0.2 1.4 1 0 0 1 1 1 0 Organic solute transporter subunit beta protein DUF4692 PF15763.5 CBK24235.2 - 0.12 12.9 0.1 0.21 12.0 0.1 1.3 1 0 0 1 1 1 0 Regulator of human erythroid cell expansion (RHEX) Baculo_11_kDa PF06143.11 CBK24235.2 - 0.27 10.8 5.9 0.54 9.9 5.9 1.4 1 0 0 1 1 1 0 Baculovirus 11 kDa family SP_C-Propep PF08999.10 CBK24235.2 - 1.2 9.0 5.4 2.5 7.9 5.4 1.5 1 0 0 1 1 1 0 Surfactant protein C, N terminal propeptide ASFV_J13L PF05568.11 CBK24235.2 - 1.5 8.6 7.8 0.28 10.9 3.6 2.0 2 0 0 2 2 2 0 African swine fever virus J13L protein DUF5385 PF17359.2 CBK24235.2 - 1.8 8.1 3.8 2.9 7.4 3.8 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5385) RAMP PF04901.13 CBK24235.2 - 2 8.5 4.1 3.7 7.6 4.1 1.4 1 0 0 1 1 1 0 Receptor activity modifying family Collectrin PF16959.5 CBK24235.2 - 2.1 8.1 6.3 4.4 7.1 6.3 1.5 1 0 0 1 1 1 0 Renal amino acid transporter CarboxypepD_reg PF13620.6 CBK24236.2 - 3.7e-29 100.8 1.8 1.5e-06 28.4 0.0 6.1 6 0 0 6 6 6 5 Carboxypeptidase regulatory-like domain DUF2012 PF09430.10 CBK24236.2 - 7.4e-10 39.0 0.0 0.27 11.4 0.0 5.5 4 2 1 5 5 5 3 Protein of unknown function (DUF2012) SdrD_B PF17210.3 CBK24236.2 - 2.8e-08 33.9 0.0 0.052 13.8 0.0 5.2 6 0 0 6 6 6 2 SdrD B-like domain CarbopepD_reg_2 PF13715.6 CBK24236.2 - 1.6e-06 28.0 0.4 0.55 10.3 0.0 4.1 4 0 0 4 4 4 2 CarboxypepD_reg-like domain Big_1 PF02369.16 CBK24236.2 - 0.00029 20.8 0.1 0.72 9.9 0.0 3.8 3 1 1 4 4 4 2 Bacterial Ig-like domain (group 1) fn3_3 PF14686.6 CBK24236.2 - 0.036 13.9 0.0 31 4.4 0.0 4.1 4 0 0 4 4 4 0 Polysaccharide lyase family 4, domain II Big_6 PF17936.1 CBK24236.2 - 0.29 11.4 4.3 50 4.3 0.7 5.6 7 0 0 7 7 7 0 Bacterial Ig domain CarboxypepD_reg PF13620.6 CBK24237.2 - 4.4e-21 74.9 0.8 2e-05 24.8 0.0 4.2 4 0 0 4 4 4 4 Carboxypeptidase regulatory-like domain SdrD_B PF17210.3 CBK24237.2 - 4e-13 49.6 0.0 1.3e-05 25.4 0.0 3.4 3 0 0 3 3 3 3 SdrD B-like domain CarbopepD_reg_2 PF13715.6 CBK24237.2 - 7e-08 32.4 0.1 0.022 14.8 0.0 4.0 4 0 0 4 4 4 2 CarboxypepD_reg-like domain bMG3 PF11974.8 CBK24237.2 - 5.6e-05 23.1 0.0 0.13 12.3 0.0 2.8 3 0 0 3 3 3 2 Bacterial alpha-2-macroglobulin MG3 domain SpaA PF17802.1 CBK24237.2 - 0.0024 18.1 0.0 5.2 7.5 0.0 3.3 3 1 0 3 3 3 2 Prealbumin-like fold domain fn3_3 PF14686.6 CBK24237.2 - 0.0036 17.0 0.3 1.7 8.4 0.0 2.9 3 0 0 3 3 3 2 Polysaccharide lyase family 4, domain II Tetraspanin PF00335.20 CBK24239.2 - 4.6e-06 26.5 13.8 4.6e-06 26.5 13.8 2.0 1 1 1 2 2 2 2 Tetraspanin family Fibrinogen_BP PF08017.11 CBK24240.2 - 1.9e-25 89.1 237.0 2.3e-12 46.0 69.5 3.2 1 1 2 3 3 3 3 Fibrinogen binding protein Peptidase_C1 PF00112.23 CBK24241.2 - 2.2e-91 305.8 15.1 8.9e-49 166.5 2.0 2.1 2 0 0 2 2 2 2 Papain family cysteine protease Pox_I6 PF04595.13 CBK24241.2 - 0.018 14.0 0.0 0.028 13.4 0.0 1.2 1 0 0 1 1 1 0 Poxvirus I6-like family Peptidase_C1_2 PF03051.15 CBK24241.2 - 0.027 13.2 6.8 0.029 13.2 0.1 2.1 2 0 0 2 2 2 0 Peptidase C1-like family AAA PF00004.29 CBK24242.2 - 0.0015 18.9 0.0 0.0028 18.1 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CBK24242.2 - 0.01 15.7 0.6 0.076 12.8 0.1 2.3 2 1 0 2 2 2 1 AAA+ lid domain Uricase PF01014.18 CBK24242.2 - 0.035 14.4 0.0 0.057 13.7 0.0 1.4 1 0 0 1 1 1 0 Uricase DUF2431 PF10354.9 CBK24242.2 - 0.071 13.4 0.1 0.092 13.0 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF2431) DUF3272 PF11676.8 CBK24243.2 - 4.7 7.5 11.7 0.15 12.3 2.9 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3272) NAC PF01849.18 CBK24244.2 - 2e-15 56.5 0.0 4.1e-15 55.5 0.0 1.5 1 0 0 1 1 1 1 NAC domain GSH_synth_ATP PF03917.17 CBK24245.2 - 5.7e-82 275.5 0.0 6.5e-82 275.3 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic glutathione synthase, ATP binding domain GSH_synthase PF03199.15 CBK24245.2 - 2.3e-26 92.3 0.2 5.4e-25 87.8 0.1 2.3 1 1 1 2 2 2 1 Eukaryotic glutathione synthase Sybindin PF04099.12 CBK24246.2 - 2.8e-11 43.5 0.0 3.2e-11 43.3 0.0 1.0 1 0 0 1 1 1 1 Sybindin-like family GPAT_N PF14829.6 CBK24246.2 - 0.11 12.5 0.0 0.12 12.3 0.0 1.1 1 0 0 1 1 1 0 Glycerol-3-phosphate acyltransferase N-terminal Dynamin_N PF00350.23 CBK24247.2 - 3.1e-08 33.8 0.0 1.9e-07 31.3 0.0 2.2 1 1 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.23 CBK24247.2 - 3.2e-06 27.2 0.0 1.8e-05 24.8 0.0 2.2 1 1 1 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 CBK24247.2 - 0.0011 18.5 0.1 0.0042 16.6 0.0 1.8 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain MFS_1 PF07690.16 CBK24247.2 - 0.056 12.4 0.3 0.091 11.7 0.3 1.2 1 0 0 1 1 1 0 Major Facilitator Superfamily AIG1 PF04548.16 CBK24247.2 - 0.073 12.4 0.2 11 5.3 0.0 2.5 2 1 0 2 2 2 0 AIG1 family RsgA_GTPase PF03193.16 CBK24247.2 - 3.2 7.6 4.9 3.5 7.5 0.0 2.9 3 1 0 3 3 3 0 RsgA GTPase Nop PF01798.18 CBK24248.2 - 1.7e-83 279.7 0.0 1.7e-83 279.7 0.0 2.0 2 0 0 2 2 2 1 snoRNA binding domain, fibrillarin NOP5NT PF08156.13 CBK24248.2 - 1.6e-21 76.4 1.5 1.6e-21 76.4 1.5 2.4 2 1 0 2 2 2 1 NOP5NT (NUC127) domain DUF2052 PF09747.9 CBK24248.2 - 0.42 10.7 18.4 0.79 9.8 18.4 1.5 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) GAGA_bind PF06217.12 CBK24248.2 - 0.52 10.5 16.0 0.8 9.9 16.0 1.3 1 0 0 1 1 1 0 GAGA binding protein-like family Med19 PF10278.9 CBK24248.2 - 2.3 8.1 28.0 6.5 6.6 28.0 1.8 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 YqfQ PF14181.6 CBK24248.2 - 3.3 7.9 22.0 6.8 6.9 22.0 1.5 1 0 0 1 1 1 0 YqfQ-like protein RR_TM4-6 PF06459.12 CBK24248.2 - 7.5 6.3 25.3 12 5.6 25.3 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Cation_efflux PF01545.21 CBK24249.2 - 1.6e-48 165.1 0.0 2.4e-48 164.5 0.0 1.2 1 0 0 1 1 1 1 Cation efflux family Zip PF02535.22 CBK24249.2 - 2.6e-07 30.2 10.6 4.6e-07 29.4 10.6 1.5 1 0 0 1 1 1 1 ZIP Zinc transporter Anoctamin PF04547.12 CBK24249.2 - 0.0003 19.8 0.0 0.18 10.6 0.2 2.3 2 0 0 2 2 2 2 Calcium-activated chloride channel DUF647 PF04884.14 CBK24249.2 - 0.00097 18.8 1.7 0.0015 18.2 0.2 1.9 2 0 0 2 2 2 1 Vitamin B6 photo-protection and homoeostasis V_ATPase_I PF01496.19 CBK24249.2 - 0.027 12.4 5.4 0.049 11.5 5.4 1.4 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF3382 PF11862.8 CBK24249.2 - 0.028 14.7 0.1 0.09 13.1 0.0 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF3382) HGTP_anticodon2 PF12745.7 CBK24249.2 - 0.085 12.4 3.6 0.15 11.6 3.6 1.3 1 0 0 1 1 1 0 Anticodon binding domain of tRNAs SDA1 PF05285.12 CBK24249.2 - 0.2 11.1 12.3 0.31 10.4 12.3 1.2 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.14 CBK24249.2 - 1 7.6 12.3 1.5 7.0 12.3 1.1 1 0 0 1 1 1 0 CDC45-like protein RNA_polI_A34 PF08208.11 CBK24249.2 - 4.1 7.4 9.9 7.5 6.6 9.7 1.5 2 0 0 2 2 2 0 DNA-directed RNA polymerase I subunit RPA34.5 Nop14 PF04147.12 CBK24249.2 - 6.3 4.9 16.2 9.5 4.3 16.2 1.1 1 0 0 1 1 1 0 Nop14-like family DBR1 PF05011.13 CBK24250.2 - 8e-08 32.8 0.1 1.3e-07 32.1 0.1 1.3 1 0 0 1 1 1 1 Lariat debranching enzyme, C-terminal domain Metallophos PF00149.28 CBK24250.2 - 8.8e-08 32.9 0.3 1.2e-07 32.4 0.3 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Yip1 PF04893.17 CBK24251.2 - 1.1e-07 31.7 15.5 1.7e-07 31.1 14.5 1.7 1 1 1 2 2 2 1 Yip1 domain ABC2_membrane_3 PF12698.7 CBK24251.2 - 1.6 7.7 16.4 2 7.4 16.4 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein DUF2374 PF09574.10 CBK24251.2 - 2.2 8.2 7.1 0.49 10.3 2.1 2.4 2 1 1 3 3 3 0 Protein of unknown function (Duf2374) zf-H2C2_5 PF13909.6 CBK24252.2 - 3e-09 36.4 15.6 3.9e-08 32.9 4.1 2.5 2 0 0 2 2 2 2 C2H2-type zinc-finger domain zf-H2C2_2 PF13465.6 CBK24252.2 - 2.9e-08 33.8 5.3 2.9e-08 33.8 5.3 3.3 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2 PF00096.26 CBK24252.2 - 4.1e-05 23.8 17.7 0.0041 17.5 2.3 2.4 2 0 0 2 2 2 2 Zinc finger, C2H2 type OrsD PF12013.8 CBK24252.2 - 0.0034 17.8 3.5 1.4 9.4 1.1 2.2 2 0 0 2 2 2 2 Orsellinic acid/F9775 biosynthesis cluster protein D zf-C2H2_4 PF13894.6 CBK24252.2 - 0.0058 17.4 14.7 0.009 16.8 2.0 2.5 2 0 0 2 2 2 1 C2H2-type zinc finger MENTAL PF10457.9 CBK24252.2 - 0.022 14.6 0.0 0.033 14.0 0.0 1.3 1 0 0 1 1 1 0 Cholesterol-capturing domain Itfg2 PF15907.5 CBK24252.2 - 0.2 10.6 0.1 0.25 10.4 0.1 1.1 1 0 0 1 1 1 0 Integrin-alpha FG-GAP repeat-containing protein 2 DUF1390 PF07150.11 CBK24252.2 - 0.7 9.6 9.8 3.2 7.4 4.2 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1390) MMR_HSR1 PF01926.23 CBK24253.2 - 3.2e-08 33.6 0.1 7e-08 32.6 0.1 1.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 CBK24253.2 - 0.0004 20.0 0.0 0.00063 19.3 0.0 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Arf PF00025.21 CBK24253.2 - 0.013 15.0 0.0 0.024 14.1 0.0 1.4 1 0 0 1 1 1 0 ADP-ribosylation factor family CDC73_C PF05179.14 CBK24254.2 - 2.5e-05 24.0 0.1 7.2e-05 22.5 0.0 1.7 2 0 0 2 2 2 1 RNA pol II accessory factor, Cdc73 family, C-terminal Ribosomal_L32e PF01655.18 CBK24255.2 - 9.4e-47 157.9 0.1 1.2e-46 157.6 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L32 Nucleotid_trans PF03407.16 CBK24256.2 - 4e-19 69.4 0.1 6.6e-19 68.7 0.1 1.3 1 0 0 1 1 1 1 Nucleotide-diphospho-sugar transferase Coatomer_WDAD PF04053.14 CBK24257.2 - 2e-93 313.9 0.0 3.6e-93 313.0 0.0 1.4 1 0 0 1 1 1 1 Coatomer WD associated region WD40 PF00400.32 CBK24257.2 - 1.1e-30 105.2 4.1 6.7e-08 33.1 0.0 6.7 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBK24257.2 - 1e-06 28.9 0.3 12 6.2 0.0 6.4 4 2 4 8 8 8 1 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 CBK24257.2 - 0.00016 20.5 0.1 0.086 11.5 0.0 2.3 1 1 1 2 2 2 2 Nucleoporin Nup120/160 PQQ_2 PF13360.6 CBK24257.2 - 0.0057 16.3 2.2 0.32 10.5 0.0 3.2 3 1 0 3 3 3 1 PQQ-like domain TPR_2 PF07719.17 CBK24257.2 - 0.097 12.8 2.6 0.37 11.0 0.1 3.2 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF4746 PF15928.5 CBK24257.2 - 0.14 11.5 15.4 0.22 10.9 15.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) RHS PF03527.14 CBK24257.2 - 0.15 11.9 0.3 0.36 10.6 0.3 1.6 1 0 0 1 1 1 0 RHS protein CENP-N PF05238.13 CBK24257.2 - 2.3 7.4 8.1 3.8 6.7 8.1 1.2 1 0 0 1 1 1 0 Kinetochore protein CHL4 like eIF3_subunit PF08597.10 CBK24257.2 - 3.4 7.5 27.2 6 6.7 27.2 1.4 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit Raftlin PF15250.6 CBK24257.2 - 4 6.1 10.0 5.9 5.5 10.0 1.1 1 0 0 1 1 1 0 Raftlin HEAT PF02985.22 CBK24258.2 - 5e-31 104.1 31.9 0.099 13.0 0.0 20.3 23 0 0 23 23 22 8 HEAT repeat HEAT_2 PF13646.6 CBK24258.2 - 1.3e-28 99.2 28.0 0.00074 19.9 0.0 14.6 8 2 6 15 15 15 7 HEAT repeats Cnd1 PF12717.7 CBK24258.2 - 3.2e-15 56.6 16.9 2.1e-05 24.6 0.2 8.3 6 1 2 8 8 8 4 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 CBK24258.2 - 8.1e-15 55.2 8.5 0.15 12.6 0.1 11.4 10 3 4 14 14 13 3 Vacuolar 14 Fab1-binding region CLASP_N PF12348.8 CBK24258.2 - 3e-13 49.9 10.2 0.025 14.2 0.1 8.8 6 4 4 10 10 10 4 CLASP N terminal Adaptin_N PF01602.20 CBK24258.2 - 6.6e-09 34.9 21.0 0.0084 14.7 0.1 8.3 5 3 3 8 8 8 4 Adaptin N terminal region HEAT_EZ PF13513.6 CBK24258.2 - 2.2e-08 34.4 37.6 2.1 9.0 0.0 15.3 15 2 2 17 17 16 2 HEAT-like repeat ParcG PF10274.9 CBK24258.2 - 5.9e-08 33.0 3.1 0.75 9.9 0.0 7.2 8 1 1 9 9 8 1 Parkin co-regulated protein Arm PF00514.23 CBK24258.2 - 0.0034 17.4 19.7 10 6.4 0.2 9.6 11 0 0 11 11 10 1 Armadillo/beta-catenin-like repeat NUC173 PF08161.12 CBK24258.2 - 0.0099 15.6 2.1 12 5.4 0.0 4.8 5 0 0 5 5 5 1 NUC173 domain RTP1_C1 PF10363.9 CBK24258.2 - 0.026 14.7 5.9 1.5 9.0 0.1 6.5 9 1 0 9 9 9 0 Required for nuclear transport of RNA pol II C-terminus 1 TFCD_C PF12612.8 CBK24258.2 - 0.043 13.6 4.5 1.4 8.7 0.2 4.1 4 0 0 4 4 4 0 Tubulin folding cofactor D C terminal Cohesin_HEAT PF12765.7 CBK24258.2 - 0.071 13.4 3.1 44 4.5 0.1 5.5 5 0 0 5 5 5 0 HEAT repeat associated with sister chromatid cohesion RNA_pol_Rbc25 PF08292.12 CBK24259.2 - 1.4e-23 83.5 2.0 8.8e-21 74.5 0.1 2.3 2 0 0 2 2 2 2 RNA polymerase III subunit Rpc25 SHS2_Rpb7-N PF03876.17 CBK24259.2 - 9e-17 61.2 0.0 1.5e-16 60.5 0.0 1.4 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 Ribosomal_S3_C PF00189.20 CBK24260.2 - 5.2e-22 78.2 1.1 1e-21 77.2 1.1 1.5 1 0 0 1 1 1 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.17 CBK24260.2 - 8.8e-11 41.5 0.2 1.7e-10 40.5 0.2 1.5 1 0 0 1 1 1 1 KH domain UN_NPL4 PF11543.8 CBK24260.2 - 0.015 15.8 0.0 0.029 14.8 0.0 1.6 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 Pro_isomerase PF00160.21 CBK24261.2 - 1.2e-49 168.6 0.1 1.4e-49 168.4 0.1 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DnaJ_CXXCXGXG PF00684.19 CBK24262.2 - 0.011 16.0 21.4 5 7.6 12.0 3.1 1 1 1 2 2 2 0 DnaJ central domain zf-rbx1 PF12678.7 CBK24262.2 - 1.6 9.1 14.7 1.7 9.0 0.9 2.3 1 1 1 2 2 2 0 RING-H2 zinc finger domain Diphthamide_syn PF01866.17 CBK24263.2 - 6.9e-114 380.4 0.1 8.2e-114 380.1 0.1 1.1 1 0 0 1 1 1 1 Putative diphthamide synthesis protein CC2D2AN-C2 PF15625.6 CBK24263.2 - 0.14 11.9 0.0 4.4 7.0 0.0 2.1 1 1 1 2 2 2 0 CC2D2A N-terminal C2 domain EamA PF00892.20 CBK24264.2 - 1.3e-12 48.0 16.6 1.8e-05 25.0 1.9 3.0 2 1 1 3 3 3 3 EamA-like transporter family UAA PF08449.11 CBK24264.2 - 0.17 11.1 13.8 0.025 13.8 5.8 2.0 1 1 0 2 2 2 0 UAA transporter family MMR_HSR1_Xtn PF16897.5 CBK24265.2 - 1.3e-40 137.7 1.0 2e-40 137.1 1.0 1.3 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain TGS PF02824.21 CBK24265.2 - 2.1e-23 82.1 0.0 4.1e-23 81.2 0.0 1.5 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.23 CBK24265.2 - 9.6e-20 70.8 0.0 2.1e-19 69.7 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 CBK24265.2 - 9.3e-11 41.5 0.2 9.3e-10 38.2 0.0 2.2 2 0 0 2 2 2 1 Ferrous iron transport protein B MeaB PF03308.16 CBK24265.2 - 0.0038 16.2 0.1 0.0092 15.0 0.1 1.6 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB Dynamin_N PF00350.23 CBK24265.2 - 0.0047 17.0 1.5 0.34 11.0 0.0 2.5 2 1 1 3 3 3 2 Dynamin family SET PF00856.28 CBK24266.2 - 4.4e-10 40.2 0.0 4.6e-10 40.1 0.0 1.1 1 0 0 1 1 1 1 SET domain zf-UBP_var PF17807.1 CBK24268.2 - 1.2e-22 79.4 2.4 4.1e-21 74.5 0.9 2.6 2 0 0 2 2 2 1 Variant UBP zinc finger zf-UBP PF02148.19 CBK24268.2 - 8.1e-20 70.9 25.4 7.5e-17 61.4 11.3 3.3 4 0 0 4 4 4 2 Zn-finger in ubiquitin-hydrolases and other protein UCH PF00443.29 CBK24268.2 - 4.2e-15 56.0 0.5 6.3e-15 55.4 0.5 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 CBK24268.2 - 0.00015 21.5 0.6 0.00015 21.5 0.6 1.8 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH PF00443.29 CBK24269.2 - 2.4e-10 40.3 0.0 2.5e-10 40.3 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 CBK24269.2 - 0.00048 19.8 0.0 0.00051 19.7 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Ribosomal_S8e PF01201.22 CBK24270.2 - 4.3e-44 150.0 0.7 4.9e-44 149.8 0.7 1.1 1 0 0 1 1 1 1 Ribosomal protein S8e SesA PF17107.5 CBK24271.2 - 0.1 12.8 0.0 0.14 12.3 0.0 1.2 1 0 0 1 1 1 0 N-terminal domain on NACHT_NTPase and P-loop NTPases Trypsin_2 PF13365.6 CBK24272.2 - 0.0073 17.2 0.1 0.017 16.0 0.1 1.8 1 1 0 1 1 1 1 Trypsin-like peptidase domain Dynein_C PF18199.1 CBK24273.2 - 0.0017 17.7 0.0 0.002 17.4 0.0 1.0 1 0 0 1 1 1 1 Dynein heavy chain C-terminal domain LMBR1 PF04791.16 CBK24274.2 - 1.2 8.0 3.9 1.3 7.8 3.9 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein ALMT PF11744.8 CBK24274.2 - 1.8 7.3 4.2 2 7.2 4.2 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter Glycos_transf_2 PF00535.26 CBK24275.2 - 1.1e-27 96.9 0.0 1.5e-27 96.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 CBK24275.2 - 1.2e-09 38.4 0.0 1.6e-09 38.0 0.0 1.3 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 CBK24275.2 - 0.0008 18.9 0.0 0.0012 18.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glyco_tranf_2_2 PF10111.9 CBK24275.2 - 0.046 13.2 0.0 0.069 12.6 0.0 1.2 1 0 0 1 1 1 0 Glycosyltransferase like family 2 DUF3842 PF12953.7 CBK24275.2 - 0.075 13.4 0.0 0.12 12.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3842) Glyco_trans_2_3 PF13632.6 CBK24275.2 - 0.14 12.1 0.0 0.17 11.7 0.0 1.2 1 0 0 1 1 1 0 Glycosyl transferase family group 2 Zn_Tnp_IS1595 PF12760.7 CBK24276.2 - 0.0017 18.3 0.4 0.77 9.8 0.2 2.5 2 0 0 2 2 2 1 Transposase zinc-ribbon domain CpXC PF14353.6 CBK24276.2 - 0.0075 16.3 2.2 0.1 12.6 1.5 2.6 1 1 2 3 3 3 1 CpXC protein zf-ribbon_3 PF13248.6 CBK24276.2 - 0.018 14.5 2.5 2.2 7.8 0.3 2.4 2 0 0 2 2 2 0 zinc-ribbon domain YhfH PF14149.6 CBK24276.2 - 0.049 13.6 0.8 1.9 8.5 0.1 2.6 2 0 0 2 2 2 0 YhfH-like protein TFIIS_C PF01096.18 CBK24276.2 - 0.067 13.1 2.9 3.7 7.5 0.2 2.6 3 0 0 3 3 3 0 Transcription factor S-II (TFIIS) zinc_ribbon_2 PF13240.6 CBK24276.2 - 0.072 12.8 5.0 3.6 7.4 0.6 2.4 2 0 0 2 2 2 0 zinc-ribbon domain DZR PF12773.7 CBK24276.2 - 0.076 13.0 0.3 0.21 11.6 0.3 1.7 1 1 0 1 1 1 0 Double zinc ribbon RNA_POL_M_15KD PF02150.16 CBK24276.2 - 0.085 12.8 2.9 6.9 6.6 0.1 2.5 2 0 0 2 2 2 0 RNA polymerases M/15 Kd subunit TF_Zn_Ribbon PF08271.12 CBK24276.2 - 0.086 12.4 2.8 4.7 6.8 1.3 3.0 2 1 0 2 2 2 0 TFIIB zinc-binding HypA PF01155.19 CBK24276.2 - 0.1 12.6 1.4 1.1 9.3 1.3 2.2 1 1 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-Mss51 PF13824.6 CBK24276.2 - 0.14 12.3 0.4 0.76 9.9 0.1 2.1 2 0 0 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 Zn-ribbon_8 PF09723.10 CBK24276.2 - 0.14 12.3 1.2 6.8 6.9 0.1 2.5 2 0 0 2 2 2 0 Zinc ribbon domain UPF0547 PF10571.9 CBK24276.2 - 0.15 12.2 4.4 0.17 12.0 0.5 2.3 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 A2L_zn_ribbon PF08792.10 CBK24276.2 - 0.18 11.5 4.8 3 7.7 0.3 2.6 2 1 0 2 2 2 0 A2L zinc ribbon domain Rpr2 PF04032.16 CBK24276.2 - 0.2 12.0 1.2 0.29 11.4 1.2 1.6 1 1 0 1 1 1 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain DUF1610 PF07754.11 CBK24276.2 - 0.2 11.6 0.4 0.2 11.6 0.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1610) zf-H2C2_2 PF13465.6 CBK24276.2 - 0.47 11.0 3.5 0.53 10.8 0.4 2.5 2 1 0 2 2 2 0 Zinc-finger double domain Rubredoxin_2 PF18073.1 CBK24276.2 - 0.95 9.2 4.1 17 5.2 0.5 2.4 2 0 0 2 2 2 0 Rubredoxin metal binding domain zf_C2H2_10 PF18414.1 CBK24276.2 - 1.3 8.7 5.4 0.21 11.1 0.6 2.0 2 0 0 2 2 2 0 C2H2 type zinc-finger zf-C2H2 PF00096.26 CBK24276.2 - 3.2 8.4 5.6 1.5 9.4 0.4 2.8 3 0 0 3 3 3 0 Zinc finger, C2H2 type zf_UBZ PF18439.1 CBK24276.2 - 5.7 6.6 7.2 2.3 7.9 0.2 2.6 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger PHD PF00628.29 CBK24278.2 - 0.0073 16.2 18.2 0.0073 16.2 18.2 2.8 3 0 0 3 3 3 2 PHD-finger zf-C2H2_3rep PF18868.1 CBK24280.2 - 0.036 14.7 0.2 0.52 11.0 0.0 2.2 2 0 0 2 2 2 0 Zinc finger C2H2-type, 3 repeats zinc_ribbon_2 PF13240.6 CBK24280.2 - 0.2 11.4 1.5 0.44 10.3 1.5 1.6 1 0 0 1 1 1 0 zinc-ribbon domain DZR PF12773.7 CBK24280.2 - 0.3 11.1 3.6 0.98 9.5 3.7 1.7 1 1 0 1 1 1 0 Double zinc ribbon Ras PF00071.22 CBK24281.2 - 2.2e-47 160.7 0.2 2.7e-47 160.4 0.2 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CBK24281.2 - 2.3e-21 76.2 0.0 4.4e-21 75.3 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CBK24281.2 - 1.4e-11 44.1 0.1 1.9e-11 43.7 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 CBK24281.2 - 5e-05 22.9 0.3 0.00013 21.6 0.1 1.6 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 CBK24281.2 - 0.0084 16.0 0.1 0.34 10.8 0.1 2.2 2 0 0 2 2 2 1 RsgA GTPase SRPRB PF09439.10 CBK24281.2 - 0.023 14.2 0.0 0.034 13.6 0.0 1.4 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit HSP20 PF00011.21 CBK24283.2 - 1.4e-27 95.8 1.2 1.8e-27 95.4 1.2 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 CBK24283.2 - 1e-13 50.6 0.0 1.9e-13 49.8 0.0 1.5 1 0 0 1 1 1 1 HSP20-like domain found in ArsA PMI_typeI PF01238.21 CBK24284.2 - 3.7e-91 306.1 0.0 4.3e-91 305.9 0.0 1.0 1 0 0 1 1 1 1 Phosphomannose isomerase type I Cupin_2 PF07883.11 CBK24284.2 - 0.073 12.8 0.0 0.34 10.6 0.0 2.0 2 0 0 2 2 2 0 Cupin domain MA3 PF02847.17 CBK24285.2 - 3.7e-16 59.1 0.4 9.8e-16 57.7 0.2 1.8 2 0 0 2 2 2 1 MA3 domain GEMIN8 PF15348.6 CBK24285.2 - 0.069 13.5 4.9 0.1 12.9 4.9 1.2 1 0 0 1 1 1 0 Gemini of Cajal bodies-associated protein 8 AMP-binding PF00501.28 CBK24286.2 - 2.5e-85 286.6 0.0 3.1e-85 286.3 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme Aminotran_1_2 PF00155.21 CBK24288.2 - 9.9e-48 163.1 0.0 1.3e-47 162.8 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 CBK24288.2 - 2.5e-05 23.7 0.0 4.9e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 Beta-eliminating lyase Hormone_1 PF00103.20 CBK24288.2 - 0.016 15.0 0.1 0.031 14.0 0.1 1.4 1 0 0 1 1 1 0 Somatotropin hormone family DNA_pol_E_B PF04042.16 CBK24288.2 - 0.11 11.8 0.0 0.22 10.9 0.0 1.4 1 0 0 1 1 1 0 DNA polymerase alpha/epsilon subunit B Orthoreo_P10 PF07204.11 CBK24289.2 - 0.00012 22.0 1.1 0.00026 20.9 1.1 1.5 1 0 0 1 1 1 1 Orthoreovirus membrane fusion protein p10 Shisa PF13908.6 CBK24289.2 - 0.00029 21.1 2.6 0.00029 21.1 2.6 2.9 1 1 1 2 2 2 1 Wnt and FGF inhibitory regulator TMEM132D_C PF15706.5 CBK24289.2 - 0.0022 17.7 0.4 0.0049 16.6 0.4 1.5 1 0 0 1 1 1 1 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term TMEM154 PF15102.6 CBK24289.2 - 0.036 14.0 10.9 0.9 9.4 10.9 2.6 1 1 0 1 1 1 0 TMEM154 protein family EphA2_TM PF14575.6 CBK24289.2 - 0.092 13.6 0.2 0.27 12.1 0.1 1.8 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Met_10 PF02475.16 CBK24290.2 - 1.1e-53 182.0 0.0 1.3e-53 181.7 0.0 1.0 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_25 PF13649.6 CBK24290.2 - 0.0043 17.7 0.0 0.018 15.8 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain TehB PF03848.14 CBK24290.2 - 0.0063 15.9 0.0 0.01 15.2 0.0 1.3 1 1 0 1 1 1 1 Tellurite resistance protein TehB Methyltransf_15 PF09445.10 CBK24290.2 - 0.013 15.1 0.0 0.021 14.4 0.0 1.3 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase tRNA_U5-meth_tr PF05958.11 CBK24290.2 - 0.028 13.4 0.0 0.041 12.9 0.0 1.3 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase MTS PF05175.14 CBK24290.2 - 0.036 13.6 0.0 0.064 12.8 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain MethyltransfD12 PF02086.15 CBK24290.2 - 0.036 13.7 0.0 0.05 13.3 0.0 1.2 1 0 0 1 1 1 0 D12 class N6 adenine-specific DNA methyltransferase PrmA PF06325.13 CBK24290.2 - 0.057 12.8 0.0 0.072 12.5 0.0 1.1 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) DNA_methylase PF00145.17 CBK24290.2 - 0.07 12.5 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 C-5 cytosine-specific DNA methylase AD PF09793.9 CBK24291.2 - 1.9e-11 43.9 0.0 2.5e-11 43.5 0.0 1.2 1 0 0 1 1 1 1 Anticodon-binding domain DDOST_48kD PF03345.14 CBK24292.2 - 3.1e-77 260.2 3.7 8.9e-43 146.7 2.3 2.0 2 0 0 2 2 2 2 Oligosaccharyltransferase 48 kDa subunit beta PAXNEB PF05625.11 CBK24293.2 - 1.6e-20 73.6 0.2 4.6e-20 72.1 0.2 1.8 1 1 0 1 1 1 1 PAXNEB protein Rad51 PF08423.11 CBK24293.2 - 0.19 10.9 0.0 0.41 9.9 0.0 1.5 2 0 0 2 2 2 0 Rad51 DNA_topoisoIV PF00521.20 CBK24295.2 - 9.3e-113 377.3 0.1 1.4e-112 376.7 0.1 1.3 1 0 0 1 1 1 1 DNA gyrase/topoisomerase IV, subunit A TOPRIM_C PF16898.5 CBK24295.2 - 5.9e-46 155.9 2.8 5.9e-46 155.9 2.8 3.3 4 0 0 4 4 4 1 C-terminal associated domain of TOPRIM DNA_gyraseB PF00204.25 CBK24295.2 - 1.4e-14 54.0 0.0 4.1e-14 52.4 0.0 1.8 1 0 0 1 1 1 1 DNA gyrase B HATPase_c PF02518.26 CBK24295.2 - 1.4e-13 51.3 0.1 2.8e-13 50.3 0.1 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Toprim PF01751.22 CBK24295.2 - 1.3e-07 31.8 0.0 6.2e-07 29.6 0.0 2.2 1 0 0 1 1 1 1 Toprim domain RRF PF01765.19 CBK24295.2 - 1.2 9.1 6.3 0.34 10.9 0.2 3.2 3 1 1 4 4 4 0 Ribosome recycling factor DUF4761 PF15958.5 CBK24296.2 - 0.1 12.8 0.0 0.13 12.5 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4761) Peptidase_C48 PF02902.19 CBK24297.2 - 1.4e-24 87.2 0.9 3.1e-24 86.0 0.9 1.6 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain DUF3450 PF11932.8 CBK24298.2 - 8.5e-05 22.0 26.1 0.0043 16.4 8.0 2.4 1 1 1 2 2 2 2 Protein of unknown function (DUF3450) Spc7 PF08317.11 CBK24298.2 - 0.00029 19.8 16.8 0.00042 19.3 16.8 1.2 1 0 0 1 1 1 1 Spc7 kinetochore protein ZapB PF06005.12 CBK24298.2 - 0.00029 21.2 22.8 0.58 10.6 20.3 2.9 1 1 1 2 2 1 1 Cell division protein ZapB IFT57 PF10498.9 CBK24298.2 - 0.0013 17.8 20.4 0.0013 17.8 20.4 1.8 1 1 1 2 2 2 1 Intra-flagellar transport protein 57 TolA_bind_tri PF16331.5 CBK24298.2 - 0.0021 18.1 19.3 0.25 11.4 12.6 3.3 1 1 1 2 2 2 2 TolA binding protein trimerisation Peptidase_S46 PF10459.9 CBK24298.2 - 0.0029 16.3 12.9 0.0038 16.0 12.9 1.2 1 0 0 1 1 1 1 Peptidase S46 ATG16 PF08614.11 CBK24298.2 - 0.0045 17.2 21.1 0.0045 17.2 21.1 2.3 2 1 1 3 3 3 1 Autophagy protein 16 (ATG16) V-SNARE PF05008.15 CBK24298.2 - 0.0071 16.7 0.3 0.0071 16.7 0.3 3.5 2 1 1 3 3 3 1 Vesicle transport v-SNARE protein N-terminus GAS PF13851.6 CBK24298.2 - 0.0074 15.7 21.9 0.017 14.4 21.2 1.7 1 1 0 1 1 1 1 Growth-arrest specific micro-tubule binding Scaffolding_pro PF11418.8 CBK24298.2 - 0.0089 16.6 0.9 0.0089 16.6 0.9 2.5 1 1 1 2 2 2 1 Phi29 scaffolding protein KELK PF15796.5 CBK24298.2 - 0.015 15.7 18.9 0.12 12.9 8.3 3.5 2 1 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase TMF_TATA_bd PF12325.8 CBK24298.2 - 0.021 15.0 3.0 0.021 15.0 3.0 3.0 2 1 0 3 3 2 0 TATA element modulatory factor 1 TATA binding Atg14 PF10186.9 CBK24298.2 - 0.029 13.4 20.5 0.044 12.9 20.5 1.4 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 CENP-F_leu_zip PF10473.9 CBK24298.2 - 0.038 14.0 20.3 0.028 14.4 16.1 2.3 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 BRE1 PF08647.11 CBK24298.2 - 0.047 13.8 23.6 0.68 10.0 3.9 2.8 1 1 0 3 3 3 0 BRE1 E3 ubiquitin ligase FUSC PF04632.12 CBK24298.2 - 0.048 12.2 10.4 0.059 11.9 10.4 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family Tup_N PF08581.10 CBK24298.2 - 0.06 13.7 15.4 0.45 10.9 5.8 3.0 3 0 0 3 3 3 0 Tup N-terminal NYD-SP28_assoc PF14775.6 CBK24298.2 - 0.061 13.4 1.1 0.061 13.4 1.1 2.4 2 0 0 2 2 2 0 Sperm tail C-terminal domain Filament PF00038.21 CBK24298.2 - 0.068 12.7 24.0 0.37 10.3 13.2 2.2 1 1 1 2 2 2 0 Intermediate filament protein KASH_CCD PF14662.6 CBK24298.2 - 0.077 12.8 22.0 0.017 15.0 18.5 1.6 2 0 0 2 2 1 0 Coiled-coil region of CCDC155 or KASH DivIC PF04977.15 CBK24298.2 - 0.078 12.8 22.8 0.49 10.2 4.8 3.2 1 1 2 3 3 3 0 Septum formation initiator OmpH PF03938.14 CBK24298.2 - 0.085 13.2 25.2 1.3 9.4 8.6 2.3 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) CCDC92 PF14916.6 CBK24298.2 - 0.14 11.9 0.2 0.14 11.9 0.2 3.4 3 1 0 3 3 3 0 Coiled-coil domain of unknown function YabA PF06156.13 CBK24298.2 - 0.16 12.6 17.4 0.37 11.4 0.9 3.1 1 1 2 3 3 3 0 Initiation control protein YabA TSNAXIP1_N PF15739.5 CBK24298.2 - 0.19 12.1 19.3 0.32 11.4 3.1 2.7 1 1 1 2 2 2 0 Translin-associated factor X-interacting N-terminus CENP-H PF05837.12 CBK24298.2 - 0.21 12.0 24.3 0.15 12.4 2.2 3.0 1 1 2 3 3 3 0 Centromere protein H (CENP-H) APG6_N PF17675.1 CBK24298.2 - 0.21 12.1 30.5 0.21 12.1 7.6 2.5 1 1 0 2 2 2 0 Apg6 coiled-coil region DUF2203 PF09969.9 CBK24298.2 - 0.29 11.9 10.4 5.1 7.8 5.8 2.6 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) DUF4407 PF14362.6 CBK24298.2 - 0.31 10.4 21.2 0.036 13.4 16.8 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) HALZ PF02183.18 CBK24298.2 - 0.43 10.8 15.7 0.92 9.8 3.3 3.3 2 1 0 2 2 2 0 Homeobox associated leucine zipper DUF724 PF05266.14 CBK24298.2 - 0.62 9.9 17.8 3.1 7.6 9.8 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF724) TMF_DNA_bd PF12329.8 CBK24298.2 - 0.63 10.1 21.0 3.2 7.8 4.3 2.8 2 1 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Fez1 PF06818.15 CBK24298.2 - 0.67 10.4 27.1 0.95 9.9 26.4 1.6 1 1 0 1 1 1 0 Fez1 DUF1773 PF08593.10 CBK24298.2 - 0.67 11.0 0.2 0.67 11.0 0.2 3.1 3 0 0 3 3 1 0 Domain of unknown function ADIP PF11559.8 CBK24298.2 - 0.7 10.0 31.8 1.1 9.4 9.5 3.2 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding DUF641 PF04859.12 CBK24298.2 - 0.74 10.2 15.8 3.4 8.0 11.4 2.6 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) UPF0242 PF06785.11 CBK24298.2 - 0.95 9.5 21.8 1 9.4 4.0 2.1 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus MbeD_MobD PF04899.12 CBK24298.2 - 1.2 9.3 19.9 0.055 13.6 2.3 3.0 3 0 0 3 3 2 0 MbeD/MobD like RasGAP_C PF03836.15 CBK24298.2 - 1.4 9.0 20.9 0.064 13.4 9.8 2.9 1 1 1 2 2 2 0 RasGAP C-terminus DUF4472 PF14739.6 CBK24298.2 - 1.8 9.3 17.3 4.4 8.1 12.5 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4472) DLP_helical PF18709.1 CBK24298.2 - 1.8 7.7 13.8 0.97 8.6 9.2 2.4 1 1 1 2 2 2 0 Dynamin-like helical domain DUF2968 PF11180.8 CBK24298.2 - 1.8 8.1 22.5 0.036 13.7 15.4 1.9 2 0 0 2 2 1 0 Protein of unknown function (DUF2968) DivIVA PF05103.13 CBK24298.2 - 2 8.5 19.6 0.62 10.1 14.9 2.1 1 1 1 2 2 2 0 DivIVA protein Snapin_Pallidin PF14712.6 CBK24298.2 - 2.3 8.7 18.9 5.9 7.4 7.8 2.9 2 1 1 3 3 3 0 Snapin/Pallidin DASH_Spc34 PF08657.10 CBK24298.2 - 2.4 7.9 24.0 3.8 7.2 12.1 2.8 1 1 1 2 2 2 0 DASH complex subunit Spc34 DUF16 PF01519.16 CBK24298.2 - 2.6 8.6 15.8 1.2e+02 3.2 15.8 2.4 1 1 0 1 1 1 0 Protein of unknown function DUF16 HAUS-augmin3 PF14932.6 CBK24298.2 - 3 7.3 22.1 1.1 8.8 5.7 2.5 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 3 ALMT PF11744.8 CBK24298.2 - 3.3 6.4 12.4 4.7 5.9 12.4 1.3 1 0 0 1 1 1 0 Aluminium activated malate transporter DUF948 PF06103.11 CBK24298.2 - 3.7 7.9 9.0 18 5.6 4.2 2.6 1 1 2 3 3 2 0 Bacterial protein of unknown function (DUF948) USP8_interact PF08941.10 CBK24298.2 - 3.9 7.2 16.4 6.1 6.6 5.7 3.1 2 1 1 3 3 3 0 USP8 interacting AAA_13 PF13166.6 CBK24298.2 - 8.6 4.9 21.8 1.2 7.7 4.8 2.1 1 1 2 3 3 3 0 AAA domain SH3_1 PF00018.28 CBK24299.2 - 7.3e-15 54.3 0.2 1.1e-06 28.1 0.0 2.2 2 0 0 2 2 2 2 SH3 domain SH3_2 PF07653.17 CBK24299.2 - 2.1e-06 27.3 0.0 0.00053 19.6 0.0 2.1 2 0 0 2 2 2 2 Variant SH3 domain SH3_9 PF14604.6 CBK24299.2 - 4.5e-05 23.2 0.2 0.18 11.7 0.1 2.2 2 0 0 2 2 2 2 Variant SH3 domain SH3_4 PF06347.13 CBK24299.2 - 0.0019 18.0 0.5 0.13 12.1 0.1 2.3 2 0 0 2 2 2 1 Bacterial SH3 domain DUF2862 PF11061.8 CBK24299.2 - 0.0053 16.6 0.4 0.012 15.4 0.4 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2862) SH3_6 PF12913.7 CBK24299.2 - 0.021 14.4 0.0 0.55 9.8 0.0 2.2 2 0 0 2 2 2 0 SH3 domain (SH3b1 type) SH3_3 PF08239.11 CBK24299.2 - 0.023 15.0 1.1 0.96 9.8 0.3 2.3 2 0 0 2 2 2 0 Bacterial SH3 domain SH3_10 PF17902.1 CBK24299.2 - 0.051 13.7 0.0 0.45 10.6 0.0 2.0 2 0 0 2 2 2 0 SH3 domain DUF1713 PF08213.11 CBK24300.2 - 3.3e-05 23.7 18.7 3.8e-05 23.5 18.7 1.1 1 0 0 1 1 1 1 Mitochondrial domain of unknown function (DUF1713) GTP_EFTU PF00009.27 CBK24302.2 - 2.6e-54 183.7 0.0 3.7e-54 183.2 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 CBK24302.2 - 4.6e-40 136.4 0.0 1.1e-39 135.2 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 CBK24302.2 - 9.8e-08 32.3 0.0 2.7e-07 30.9 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 CBK24302.2 - 0.00011 22.2 0.1 0.0023 18.0 0.1 2.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase He_PIG PF05345.12 CBK24303.2 - 0.0025 18.0 0.0 0.0077 16.4 0.0 1.9 1 0 0 1 1 1 1 Putative Ig domain Sushi PF00084.20 CBK24303.2 - 0.34 11.5 5.0 0.16 12.6 1.1 2.3 2 0 0 2 2 2 0 Sushi repeat (SCR repeat) DNA_pol_B_2 PF03175.13 CBK24304.2 - 3.6e-17 62.4 12.8 1.3e-14 54.0 8.7 2.4 2 0 0 2 2 2 2 DNA polymerase type B, organellar and viral HA2 PF04408.23 CBK24305.2 - 1.5e-23 83.1 0.0 3.1e-23 82.1 0.0 1.5 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 CBK24305.2 - 2e-20 72.9 0.0 4.2e-20 71.9 0.0 1.5 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 CBK24305.2 - 1.9e-14 53.9 0.0 4.5e-14 52.7 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 CBK24305.2 - 1e-07 31.9 0.1 2.1e-07 30.9 0.1 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_19 PF13245.6 CBK24305.2 - 3.8e-06 27.3 0.1 8.2e-06 26.2 0.1 1.5 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 CBK24305.2 - 7.5e-05 21.9 0.0 0.00016 20.9 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_22 PF13401.6 CBK24305.2 - 0.00056 20.2 0.0 0.0014 18.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain SRP54 PF00448.22 CBK24305.2 - 0.0017 18.0 0.0 0.0039 16.8 0.0 1.6 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain AAA_30 PF13604.6 CBK24305.2 - 0.0039 16.9 0.0 0.0065 16.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain ResIII PF04851.15 CBK24305.2 - 0.0051 16.8 0.0 0.031 14.3 0.0 2.1 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DUF2075 PF09848.9 CBK24305.2 - 0.03 13.6 0.0 0.044 13.0 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) ABC_tran PF00005.27 CBK24305.2 - 0.13 12.7 0.2 4.1 7.9 0.2 2.4 1 1 0 1 1 1 0 ABC transporter Sigma54_activat PF00158.26 CBK24305.2 - 0.19 11.4 0.0 0.36 10.5 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain CTP_synth_N PF06418.14 CBK24306.2 - 9.3e-125 415.3 0.1 1.2e-124 414.9 0.1 1.2 1 0 0 1 1 1 1 CTP synthase N-terminus GATase PF00117.28 CBK24306.2 - 6.4e-51 172.8 0.0 9.7e-51 172.2 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 CBK24306.2 - 2.1e-06 27.7 0.0 5.2e-06 26.4 0.0 1.7 1 0 0 1 1 1 1 Peptidase C26 CbiA PF01656.23 CBK24306.2 - 0.023 14.7 0.0 0.059 13.4 0.0 1.5 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain HEAT PF02985.22 CBK24307.2 - 0.00024 21.1 0.1 0.46 10.9 0.0 4.6 4 0 0 4 4 4 1 HEAT repeat HEAT_2 PF13646.6 CBK24307.2 - 0.081 13.3 0.0 0.32 11.4 0.0 2.1 1 0 0 1 1 1 0 HEAT repeats Cnd1 PF12717.7 CBK24307.2 - 0.28 11.2 2.2 4.1 7.4 0.0 3.3 2 1 0 3 3 3 0 non-SMC mitotic condensation complex subunit 1 TSP_NTD PF17804.1 CBK24308.2 - 0.029 14.6 0.9 0.12 12.6 0.0 2.0 2 0 0 2 2 2 0 Tail specific protease N-terminal domain FANCI_S2 PF14676.6 CBK24308.2 - 0.045 14.1 2.0 0.086 13.1 0.2 2.2 2 1 1 3 3 3 0 FANCI solenoid 2 RLL PF10036.9 CBK24308.2 - 0.073 12.9 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 RNA transcription, translation and transport factor protein HA2 PF04408.23 CBK24309.2 - 4.8e-23 81.5 0.0 1e-22 80.4 0.0 1.5 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 CBK24309.2 - 2.8e-19 69.2 0.0 5.7e-19 68.3 0.0 1.5 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 CBK24309.2 - 1.1e-14 54.7 0.0 2.5e-14 53.5 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 CBK24309.2 - 1.1e-07 31.8 0.1 2.2e-07 30.8 0.1 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_19 PF13245.6 CBK24309.2 - 3.5e-06 27.4 0.1 8.6e-06 26.1 0.1 1.6 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 CBK24309.2 - 8.1e-05 21.8 0.0 0.00016 20.8 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_22 PF13401.6 CBK24309.2 - 0.00054 20.2 0.0 0.0015 18.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain SRP54 PF00448.22 CBK24309.2 - 0.0017 18.1 0.0 0.0042 16.7 0.0 1.7 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain AAA_30 PF13604.6 CBK24309.2 - 0.004 16.9 0.0 0.0068 16.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain ResIII PF04851.15 CBK24309.2 - 0.0055 16.7 0.0 0.033 14.2 0.0 2.1 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DUF2075 PF09848.9 CBK24309.2 - 0.03 13.6 0.0 0.046 12.9 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) PhoH PF02562.16 CBK24309.2 - 0.074 12.5 0.0 0.68 9.3 0.0 2.4 3 0 0 3 3 3 0 PhoH-like protein ABC_tran PF00005.27 CBK24309.2 - 0.085 13.4 0.2 4.3 7.9 0.2 2.8 2 1 0 2 2 2 0 ABC transporter AAA_23 PF13476.6 CBK24309.2 - 0.13 12.7 0.0 0.29 11.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 CBK24309.2 - 0.19 11.5 0.0 0.37 10.5 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain DnaJ PF00226.31 CBK24310.2 - 1.3e-19 70.0 1.2 2.5e-19 69.1 1.2 1.5 1 0 0 1 1 1 1 DnaJ domain CNDH2_N PF06278.11 CBK24310.2 - 0.11 12.8 1.5 0.17 12.1 1.5 1.4 1 0 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, N-terminal DUF2220 PF09983.9 CBK24310.2 - 1.3 8.4 6.2 4.9 6.5 6.1 1.8 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria C-term(DUF2220) tRNA_bind PF01588.20 CBK24311.2 - 1.7e-26 92.2 0.0 3.3e-26 91.2 0.0 1.5 1 0 0 1 1 1 1 Putative tRNA binding domain DEAD PF00270.29 CBK24312.2 - 2.5e-44 151.2 0.2 4.1e-44 150.4 0.2 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CBK24312.2 - 1.7e-24 86.3 0.4 1.7e-22 79.8 0.1 2.9 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 CBK24312.2 - 3.4e-05 23.9 0.0 5.7e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 CBK24312.2 - 0.0024 18.2 0.1 0.011 16.0 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 CBK24312.2 - 0.035 13.8 0.0 0.057 13.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain CMS1 PF14617.6 CBK24312.2 - 0.046 13.0 0.0 0.11 11.8 0.0 1.6 1 1 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit Fanconi_A PF03511.14 CBK24312.2 - 0.13 12.1 0.1 0.5 10.3 0.0 2.0 2 0 0 2 2 2 0 Fanconi anaemia group A protein Ribosomal_L14e PF01929.17 CBK24313.2 - 1e-25 90.0 3.3 1.2e-25 89.8 3.3 1.1 1 0 0 1 1 1 1 Ribosomal protein L14 KOW PF00467.29 CBK24313.2 - 0.0012 18.7 0.0 0.0019 18.1 0.0 1.4 1 0 0 1 1 1 1 KOW motif Pox_J1 PF03338.15 CBK24313.2 - 0.033 14.1 0.1 0.17 11.8 0.0 1.9 1 1 1 2 2 2 0 Poxvirus J1 protein WD40 PF00400.32 CBK24314.2 - 3e-31 107.0 25.8 2.1e-07 31.5 0.1 6.0 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBK24314.2 - 3.3e-06 27.3 0.6 1 9.7 0.0 4.0 2 1 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 CBK24314.2 - 8.4e-06 24.7 4.5 0.11 11.1 0.0 4.0 3 1 0 4 4 4 3 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 CBK24314.2 - 0.029 13.3 6.3 0.29 10.0 1.2 2.9 2 2 1 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Cytochrom_D1 PF02239.16 CBK24314.2 - 0.038 12.5 0.1 0.16 10.4 0.1 1.7 1 1 1 2 2 2 0 Cytochrome D1 heme domain SH3_1 PF00018.28 CBK24315.2 - 6.7e-13 48.0 0.1 1.4e-12 47.0 0.1 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 CBK24315.2 - 2e-12 46.8 0.0 3.7e-12 45.9 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 CBK24315.2 - 1.2e-10 40.9 0.0 2.4e-10 39.9 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain BAR PF03114.18 CBK24315.2 - 3.2e-07 30.2 5.9 7.5e-06 25.8 4.6 2.9 1 1 1 2 2 2 2 BAR domain BAR_3 PF16746.5 CBK24315.2 - 0.0057 16.4 1.4 0.1 12.3 0.1 2.2 1 1 1 2 2 2 1 BAR domain of APPL family DUF1664 PF07889.12 CBK24315.2 - 2.9 7.9 4.9 3.2 7.8 0.1 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) TP_methylase PF00590.20 CBK24316.2 - 2.8e-22 79.7 0.0 4.9e-22 78.9 0.0 1.4 1 1 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases Pkinase PF00069.25 CBK24317.2 - 5.7e-69 232.4 0.0 6.5e-69 232.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBK24317.2 - 2.8e-29 102.2 0.0 3.9e-29 101.7 0.0 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CBK24317.2 - 5.8e-05 22.5 0.0 0.0081 15.5 0.0 2.1 1 1 1 2 2 2 2 Kinase-like APH PF01636.23 CBK24317.2 - 0.00082 19.4 0.0 0.0023 17.9 0.0 1.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 CBK24317.2 - 0.026 13.9 0.0 0.079 12.3 0.0 1.8 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 CBK24317.2 - 0.04 12.7 0.0 1.5 7.5 0.0 2.1 2 0 0 2 2 2 0 Fungal protein kinase Haspin_kinase PF12330.8 CBK24317.2 - 0.12 11.3 0.0 0.16 10.9 0.0 1.4 1 1 0 1 1 1 0 Haspin like kinase domain zf-RING_2 PF13639.6 CBK24318.2 - 1.1e-06 28.8 15.5 1.9e-06 28.1 15.5 1.4 1 0 0 1 1 1 1 Ring finger domain FANCL_C PF11793.8 CBK24318.2 - 0.00012 22.2 10.4 0.00069 19.7 10.4 2.1 1 1 0 1 1 1 1 FANCL C-terminal domain zf-ANAPC11 PF12861.7 CBK24318.2 - 0.00085 19.3 5.3 0.0016 18.5 5.3 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING-like PF08746.11 CBK24318.2 - 0.003 17.8 6.3 0.003 17.8 6.3 1.7 2 0 0 2 2 2 1 RING-like domain RINGv PF12906.7 CBK24318.2 - 0.0082 16.3 11.6 0.014 15.5 11.6 1.4 1 0 0 1 1 1 1 RING-variant domain zf-rbx1 PF12678.7 CBK24318.2 - 0.059 13.7 14.9 0.19 12.1 14.9 1.8 1 1 0 1 1 1 0 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 CBK24318.2 - 0.094 12.6 14.6 0.18 11.7 14.6 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 CBK24318.2 - 0.41 10.3 11.0 1.1 8.9 11.0 1.7 1 1 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-C3HC4_3 PF13920.6 CBK24318.2 - 0.68 9.8 12.9 2 8.4 12.9 1.8 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) CS PF04969.16 CBK24319.2 - 0.0017 19.3 0.8 0.0053 17.7 0.1 2.2 2 1 0 2 2 2 1 CS domain ATP-synt_C PF00137.21 CBK24320.2 - 2e-33 114.5 35.2 1.5e-20 73.3 15.3 2.1 2 0 0 2 2 2 2 ATP synthase subunit C DUF2970 PF11174.8 CBK24320.2 - 0.098 12.5 0.7 0.098 12.5 0.7 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF2970) KRTAP PF11759.8 CBK24320.2 - 1.6 9.3 8.3 1.3 9.6 4.0 2.2 2 0 0 2 2 2 0 Keratin-associated matrix FAIM1 PF06905.13 CBK24321.2 - 2e-08 34.2 0.0 3.5e-08 33.4 0.0 1.3 1 0 0 1 1 1 1 Fas apoptotic inhibitory molecule (FAIM1) DUF5102 PF17104.5 CBK24321.2 - 0.086 12.9 5.4 0.12 12.4 5.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5102) Nop14 PF04147.12 CBK24321.2 - 0.53 8.4 21.0 0.62 8.2 21.0 1.0 1 0 0 1 1 1 0 Nop14-like family Sec62 PF03839.16 CBK24321.2 - 1.7 8.1 3.8 2.3 7.7 3.8 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 Med17 PF10156.9 CBK24321.2 - 1.8 7.2 12.4 2.2 6.9 12.4 1.1 1 0 0 1 1 1 0 Subunit 17 of Mediator complex CDC45 PF02724.14 CBK24321.2 - 2.4 6.3 12.2 2.4 6.3 12.2 1.1 1 0 0 1 1 1 0 CDC45-like protein BUD22 PF09073.10 CBK24321.2 - 9.1 5.5 15.6 11 5.2 15.6 1.1 1 0 0 1 1 1 0 BUD22 YpjP PF14005.6 CBK24322.2 - 0.02 15.0 16.3 1 9.4 1.9 3.8 1 1 2 3 3 3 0 YpjP-like protein Euplotes_phero PF05842.11 CBK24322.2 - 0.029 14.9 17.3 0.58 10.7 1.1 4.8 1 1 3 4 4 4 0 Euplotes octocarinatus mating pheromone protein COMPASS-Shg1 PF05205.12 CBK24322.2 - 0.92 10.2 12.5 0.56 11.0 4.9 2.2 1 1 1 2 2 2 0 COMPASS (Complex proteins associated with Set1p) component shg1 Trypan_PARP PF05887.11 CBK24322.2 - 8.9 6.3 44.3 11 6.0 22.7 3.7 1 1 3 4 4 4 0 Procyclic acidic repetitive protein (PARP) SDA1 PF05285.12 CBK24325.2 - 0.00052 19.5 24.5 0.00061 19.3 24.5 1.1 1 0 0 1 1 1 1 SDA1 Nop14 PF04147.12 CBK24325.2 - 0.00056 18.3 24.4 0.00056 18.3 24.4 1.2 1 0 0 1 1 1 1 Nop14-like family CDC45 PF02724.14 CBK24325.2 - 0.0025 16.2 15.0 0.0026 16.1 15.0 1.1 1 0 0 1 1 1 1 CDC45-like protein Zip PF02535.22 CBK24325.2 - 0.066 12.4 4.3 0.064 12.5 4.3 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter RR_TM4-6 PF06459.12 CBK24325.2 - 0.07 13.0 22.9 0.11 12.3 22.9 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 CCSAP PF15748.5 CBK24325.2 - 0.14 12.3 14.9 0.21 11.7 14.9 1.3 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated DUF5427 PF10310.9 CBK24325.2 - 0.36 9.7 19.6 0.56 9.1 19.6 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5427) DUF2151 PF10221.9 CBK24325.2 - 0.4 9.2 9.3 0.39 9.3 9.3 1.1 1 0 0 1 1 1 0 Cell cycle and development regulator IER PF05760.12 CBK24325.2 - 0.4 11.0 5.3 0.42 10.9 5.3 1.2 1 0 0 1 1 1 0 Immediate early response protein (IER) LAP1C PF05609.12 CBK24325.2 - 0.5 9.4 13.4 0.57 9.2 13.4 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Presenilin PF01080.17 CBK24325.2 - 0.59 8.8 15.2 0.68 8.6 15.2 1.1 1 0 0 1 1 1 0 Presenilin Hid1 PF12722.7 CBK24325.2 - 0.7 8.0 12.3 0.69 8.0 12.3 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Peptidase_S64 PF08192.11 CBK24325.2 - 0.7 8.3 4.0 0.82 8.1 4.0 1.1 1 0 0 1 1 1 0 Peptidase family S64 Mpp10 PF04006.12 CBK24325.2 - 0.81 8.1 34.8 1.2 7.5 34.8 1.2 1 0 0 1 1 1 0 Mpp10 protein DUF4746 PF15928.5 CBK24325.2 - 0.93 8.9 32.7 1.4 8.3 32.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) NPR3 PF03666.13 CBK24325.2 - 0.97 8.1 10.3 1.3 7.8 10.3 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Plasmodium_Vir PF05795.11 CBK24325.2 - 2.1 7.7 16.0 2.9 7.2 16.0 1.2 1 0 0 1 1 1 0 Plasmodium vivax Vir protein COPI_C PF06957.11 CBK24325.2 - 2.9 6.6 19.8 4.8 5.8 19.8 1.3 1 1 0 1 1 1 0 Coatomer (COPI) alpha subunit C-terminus DUF4045 PF13254.6 CBK24325.2 - 2.9 7.4 15.8 3.7 7.1 15.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) Raftlin PF15250.6 CBK24325.2 - 3.9 6.1 11.8 5.4 5.7 11.8 1.2 1 0 0 1 1 1 0 Raftlin SLC12 PF03522.15 CBK24325.2 - 5.1 6.0 9.3 6.8 5.6 9.3 1.2 1 0 0 1 1 1 0 Solute carrier family 12 Roughex PF06020.11 CBK24325.2 - 6.2 5.8 24.4 8.5 5.4 24.4 1.1 1 0 0 1 1 1 0 Drosophila roughex protein PPL5 PF18168.1 CBK24325.2 - 8.6 5.6 8.8 13 5.0 8.8 1.3 1 0 0 1 1 1 0 Prim-pol family 5 MDM10 PF12519.8 CBK24325.2 - 9.1 5.0 8.8 10 4.9 8.8 1.2 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 CobT PF06213.12 CBK24325.2 - 9.8 5.5 36.9 15 4.9 36.9 1.3 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Gcd10p PF04189.13 CBK24326.2 - 6.9e-49 166.6 0.0 1.2e-48 165.8 0.0 1.3 1 0 0 1 1 1 1 Gcd10p family HSP70 PF00012.20 CBK24327.2 - 9e-62 209.1 0.2 1.2e-61 208.7 0.2 1.1 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 CBK24327.2 - 3.2e-14 52.5 1.5 6.5e-14 51.5 1.5 1.5 1 0 0 1 1 1 1 MreB/Mbl protein StbA PF06406.11 CBK24327.2 - 3.3e-06 26.6 0.6 8.8e-05 21.9 0.6 2.2 1 1 0 1 1 1 1 StbA protein FtsA PF14450.6 CBK24327.2 - 0.012 16.0 0.4 0.25 11.8 0.1 2.3 2 0 0 2 2 2 0 Cell division protein FtsA DUF2237 PF09996.9 CBK24327.2 - 0.04 13.9 0.3 0.098 12.7 0.3 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2237) SR-25 PF10500.9 CBK24329.2 - 8.9 5.8 8.0 13 5.3 8.0 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Phos_pyr_kin PF08543.12 CBK24330.2 - 5.4e-82 274.9 0.0 7.8e-82 274.3 0.0 1.3 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase TENA_THI-4 PF03070.16 CBK24330.2 - 3.2e-16 59.8 0.3 5.7e-16 59.0 0.3 1.3 1 0 0 1 1 1 1 TENA/THI-4/PQQC family PfkB PF00294.24 CBK24330.2 - 1.4e-08 34.4 0.0 5e-08 32.6 0.0 1.8 1 1 1 2 2 2 1 pfkB family carbohydrate kinase Imm72 PF15584.6 CBK24330.2 - 0.014 15.5 0.0 0.031 14.4 0.0 1.5 1 0 0 1 1 1 0 Immunity protein 72 GILT PF03227.16 CBK24331.2 - 1.9e-22 79.5 0.1 3.3e-22 78.8 0.1 1.4 1 0 0 1 1 1 1 Gamma interferon inducible lysosomal thiol reductase (GILT) DEAD PF00270.29 CBK24332.2 - 2.1e-42 144.8 0.0 3.1e-42 144.3 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CBK24332.2 - 1.9e-28 99.0 0.1 3.6e-28 98.1 0.1 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 CBK24332.2 - 8.2e-05 22.7 0.0 0.00019 21.5 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF3549 PF12069.8 CBK24332.2 - 0.055 12.5 0.1 0.75 8.8 0.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3549) Hydrolase_4 PF12146.8 CBK24334.2 - 8.7e-10 38.3 0.0 5.3e-06 25.9 0.0 2.1 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_2 PF02230.16 CBK24334.2 - 6e-06 26.2 0.0 8.7e-06 25.7 0.0 1.3 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase FSH1 PF03959.13 CBK24334.2 - 0.00012 21.8 0.0 0.00019 21.2 0.0 1.3 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_1 PF00561.20 CBK24334.2 - 0.00017 21.3 0.2 0.015 14.9 0.2 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 CBK24334.2 - 0.011 15.2 0.0 0.03 13.8 0.0 1.6 2 0 0 2 2 2 0 Prolyl oligopeptidase family DLH PF01738.18 CBK24334.2 - 0.083 12.4 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 Dienelactone hydrolase family TFIIS_C PF01096.18 CBK24335.2 - 2.5e-18 65.6 3.7 2.5e-18 65.6 3.7 2.5 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.16 CBK24335.2 - 1.5e-06 28.0 1.0 1.5e-06 28.0 1.0 2.7 3 0 0 3 3 3 1 RNA polymerases M/15 Kd subunit Zn_Tnp_IS1595 PF12760.7 CBK24335.2 - 0.00058 19.8 10.6 0.0012 18.8 1.3 2.3 2 0 0 2 2 2 1 Transposase zinc-ribbon domain DZR PF12773.7 CBK24335.2 - 0.0018 18.2 9.3 0.016 15.2 0.9 2.4 2 1 0 2 2 2 2 Double zinc ribbon Mut7-C PF01927.16 CBK24335.2 - 0.0024 18.0 0.7 0.0037 17.4 0.7 1.3 1 0 0 1 1 1 1 Mut7-C RNAse domain TF_Zn_Ribbon PF08271.12 CBK24335.2 - 0.0059 16.1 0.3 0.0059 16.1 0.3 2.9 2 2 0 2 2 2 1 TFIIB zinc-binding DUF3268 PF11672.8 CBK24335.2 - 0.0065 16.8 1.2 0.0065 16.8 1.2 2.3 2 1 0 2 2 2 1 zinc-finger-containing domain Lar_restr_allev PF14354.6 CBK24335.2 - 0.0076 16.6 4.8 0.22 11.9 0.7 2.3 2 0 0 2 2 2 2 Restriction alleviation protein Lar PyrI_C PF02748.15 CBK24335.2 - 0.0081 16.0 3.1 0.77 9.7 0.3 2.4 1 1 1 2 2 2 2 Aspartate carbamoyltransferase regulatory chain, metal binding domain Terminase_GpA PF05876.12 CBK24335.2 - 0.0094 14.6 1.4 0.0094 14.6 1.4 1.6 2 0 0 2 2 2 1 Phage terminase large subunit (GpA) zinc-ribbons_6 PF07191.12 CBK24335.2 - 0.019 15.0 10.2 0.35 10.9 1.5 2.5 2 1 0 2 2 2 0 zinc-ribbons YacG PF03884.14 CBK24335.2 - 0.51 10.1 7.3 4.2 7.2 0.1 2.7 3 0 0 3 3 3 0 DNA gyrase inhibitor YacG zf-ribbon_3 PF13248.6 CBK24335.2 - 0.82 9.2 13.1 1.9 8.0 0.3 3.9 4 0 0 4 4 4 0 zinc-ribbon domain IBR PF01485.21 CBK24335.2 - 5.6 7.3 8.9 9.4e+02 0.1 8.9 2.9 1 1 0 1 1 1 0 IBR domain, a half RING-finger domain Nudix_N_2 PF14803.6 CBK24335.2 - 6.2 6.8 14.7 0.5 10.3 3.3 3.2 2 2 0 2 2 2 0 Nudix N-terminal Baculo_LEF5_C PF11792.8 CBK24335.2 - 6.3 6.6 8.7 0.1 12.3 1.0 1.9 2 0 0 2 2 2 0 Baculoviridae late expression factor 5 C-terminal domain zf-IS66 PF13005.7 CBK24335.2 - 7.9 7.0 9.9 4.5 7.7 0.4 3.5 4 0 0 4 4 4 0 zinc-finger binding domain of transposase IS66 Lung_7-TM_R PF06814.13 CBK24336.2 - 2.2e-17 63.3 1.7 2.9e-17 62.8 1.7 1.1 1 0 0 1 1 1 1 Lung seven transmembrane receptor zf-RING_2 PF13639.6 CBK24337.2 - 2.7e-11 43.6 14.1 5.2e-11 42.7 14.1 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 CBK24337.2 - 2.9e-11 43.0 12.4 2.9e-11 43.0 12.4 1.7 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 CBK24337.2 - 2.4e-10 40.1 10.9 4.2e-10 39.3 10.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CBK24337.2 - 2.7e-10 40.1 5.6 2.7e-10 40.1 5.6 1.8 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4 PF00097.25 CBK24337.2 - 3.4e-10 39.6 11.9 5.9e-10 38.8 11.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 CBK24337.2 - 3.6e-08 33.4 10.8 8.1e-08 32.3 10.8 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 CBK24337.2 - 6.4e-07 29.1 11.7 7.9e-07 28.8 9.7 2.0 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-rbx1 PF12678.7 CBK24337.2 - 1.8e-06 28.1 12.7 4.7e-06 26.8 12.6 1.6 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 CBK24337.2 - 4.5e-06 26.5 13.5 2.3e-05 24.2 13.7 1.9 1 1 1 2 2 2 1 zinc-RING finger domain U-box PF04564.15 CBK24337.2 - 0.00059 20.0 0.0 0.0011 19.1 0.0 1.4 1 0 0 1 1 1 1 U-box domain zf-Nse PF11789.8 CBK24337.2 - 0.0052 16.6 8.0 0.0088 15.8 8.0 1.3 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_6 PF14835.6 CBK24337.2 - 0.0079 16.0 4.0 0.015 15.1 4.0 1.4 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-ANAPC11 PF12861.7 CBK24337.2 - 0.015 15.4 8.2 0.037 14.1 8.2 1.6 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Rad50_zn_hook PF04423.14 CBK24337.2 - 0.016 15.0 4.5 0.43 10.4 0.2 2.4 2 0 0 2 2 2 0 Rad50 zinc hook motif zf-RING_4 PF14570.6 CBK24337.2 - 0.033 14.0 12.5 0.29 11.0 9.8 2.5 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain Zn_ribbon_17 PF17120.5 CBK24337.2 - 0.052 13.2 7.3 0.091 12.4 7.3 1.3 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-RING_11 PF17123.5 CBK24337.2 - 0.17 11.7 8.9 0.089 12.6 5.9 2.1 2 0 0 2 2 2 0 RING-like zinc finger zf-UDP PF14569.6 CBK24337.2 - 0.19 11.9 6.7 1.6 8.9 1.0 2.2 1 1 1 2 2 2 0 Zinc-binding RING-finger zf-RING_10 PF16685.5 CBK24337.2 - 0.25 11.5 8.4 0.5 10.6 8.4 1.4 1 0 0 1 1 1 0 zinc RING finger of MSL2 DZR PF12773.7 CBK24337.2 - 0.34 11.0 10.4 0.98 9.5 10.5 1.6 1 1 0 1 1 1 0 Double zinc ribbon zinc-ribbons_6 PF07191.12 CBK24337.2 - 0.48 10.4 9.3 0.87 9.6 9.3 1.4 1 0 0 1 1 1 0 zinc-ribbons Prok-RING_1 PF14446.6 CBK24337.2 - 0.56 10.2 7.7 1.4 8.9 0.0 2.3 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 zf-P11 PF03854.14 CBK24337.2 - 2 8.2 9.0 27 4.5 9.1 2.3 1 1 1 2 2 2 0 P-11 zinc finger DpnI PF06044.12 CBK24337.2 - 4.1 7.0 7.6 18 4.9 0.2 2.2 1 1 1 2 2 2 0 Dam-replacing family OrfB_Zn_ribbon PF07282.11 CBK24337.2 - 4.5 7.3 7.1 5.6 7.0 0.2 2.3 1 1 1 2 2 2 0 Putative transposase DNA-binding domain zf-ribbon_3 PF13248.6 CBK24338.2 - 0.0041 16.5 1.6 0.0072 15.7 1.6 1.3 1 0 0 1 1 1 1 zinc-ribbon domain zinc_ribbon_2 PF13240.6 CBK24338.2 - 0.014 15.1 0.4 0.025 14.3 0.4 1.4 1 0 0 1 1 1 0 zinc-ribbon domain DZR PF12773.7 CBK24338.2 - 0.035 14.1 0.4 0.059 13.4 0.4 1.3 1 0 0 1 1 1 0 Double zinc ribbon zf-RanBP PF00641.18 CBK24338.2 - 0.13 11.6 5.5 0.23 10.8 5.5 1.4 1 0 0 1 1 1 0 Zn-finger in Ran binding protein and others Rubredoxin_2 PF18073.1 CBK24338.2 - 0.41 10.4 5.4 8.2 6.3 0.2 2.3 2 0 0 2 2 2 0 Rubredoxin metal binding domain NAD_binding_5 PF07994.12 CBK24339.2 - 9.4e-143 475.4 0.0 1.1e-142 475.2 0.0 1.0 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase Inos-1-P_synth PF01658.17 CBK24339.2 - 5e-45 152.2 0.7 1.1e-44 151.1 0.1 1.9 2 0 0 2 2 2 1 Myo-inositol-1-phosphate synthase Asp-B-Hydro_N PF05279.11 CBK24340.2 - 0.033 14.3 17.5 0.044 13.9 17.5 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region DUF2052 PF09747.9 CBK24340.2 - 0.033 14.3 13.5 0.042 14.0 13.5 1.2 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) SDA1 PF05285.12 CBK24340.2 - 0.046 13.1 15.4 0.055 12.9 15.4 1.1 1 0 0 1 1 1 0 SDA1 CPSF100_C PF13299.6 CBK24340.2 - 0.13 12.5 8.0 0.2 11.8 8.0 1.4 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Paf1 PF03985.13 CBK24340.2 - 0.19 10.7 17.3 0.22 10.5 17.3 1.1 1 0 0 1 1 1 0 Paf1 RR_TM4-6 PF06459.12 CBK24340.2 - 0.23 11.3 14.3 0.27 11.0 14.3 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 RNA_polI_A34 PF08208.11 CBK24340.2 - 0.37 10.9 18.9 0.47 10.5 18.9 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 DUF913 PF06025.12 CBK24340.2 - 0.4 9.6 6.1 0.49 9.3 6.1 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) RNA_pol_Rpc4 PF05132.14 CBK24340.2 - 0.43 11.0 8.2 0.59 10.5 8.2 1.4 1 0 0 1 1 1 0 RNA polymerase III RPC4 CDC45 PF02724.14 CBK24340.2 - 0.72 8.1 11.6 0.78 8.0 11.6 1.1 1 0 0 1 1 1 0 CDC45-like protein Na_trans_assoc PF06512.13 CBK24340.2 - 0.82 9.9 13.7 1 9.6 13.7 1.1 1 0 0 1 1 1 0 Sodium ion transport-associated TRAP_alpha PF03896.16 CBK24340.2 - 1.4 8.0 8.5 2.3 7.4 8.5 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Pox_Ag35 PF03286.14 CBK24340.2 - 2.1 8.1 15.2 3 7.6 15.2 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Presenilin PF01080.17 CBK24340.2 - 2.4 6.9 7.6 2.6 6.7 7.6 1.1 1 0 0 1 1 1 0 Presenilin SpoIIP PF07454.11 CBK24340.2 - 2.4 7.6 11.7 3.1 7.2 11.7 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Hid1 PF12722.7 CBK24340.2 - 3.1 5.8 5.5 3.4 5.7 5.5 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein CobT PF06213.12 CBK24340.2 - 3.7 6.9 16.6 4.9 6.5 16.6 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT RRN3 PF05327.11 CBK24340.2 - 6.9 5.1 7.9 8.3 4.8 7.9 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 DUF4637 PF15470.6 CBK24340.2 - 7.1 6.3 19.4 13 5.4 19.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) TERB2 PF15101.6 CBK24340.2 - 9.8 6.2 6.9 14 5.6 6.9 1.2 1 0 0 1 1 1 0 Telomere-associated protein TERB2 COG7 PF10191.9 CBK24341.2 - 2.7e-25 88.8 5.7 2.9e-25 88.7 5.7 1.2 1 0 0 1 1 1 1 Golgi complex component 7 (COG7) TolA_bind_tri PF16331.5 CBK24341.2 - 0.0064 16.5 0.1 0.0064 16.5 0.1 3.0 2 1 0 2 2 2 1 TolA binding protein trimerisation Nup54 PF13874.6 CBK24341.2 - 0.02 15.0 3.4 0.02 15.0 3.4 2.3 1 1 2 3 3 3 0 Nucleoporin complex subunit 54 Comm PF15957.5 CBK24341.2 - 0.059 13.7 1.0 0.69 10.3 0.5 2.2 2 0 0 2 2 2 0 Commissureless Sipho_Gp157 PF05565.11 CBK24341.2 - 0.073 13.1 1.9 0.83 9.7 0.1 2.3 2 0 0 2 2 2 0 Siphovirus Gp157 PCRF PF03462.18 CBK24341.2 - 0.21 11.5 3.5 0.3 10.9 2.6 1.7 1 1 1 2 2 2 0 PCRF domain YvrJ PF12841.7 CBK24341.2 - 0.29 10.7 1.1 1.1 8.9 0.1 2.5 2 0 0 2 2 2 0 YvrJ protein family Spectrin PF00435.21 CBK24341.2 - 0.51 10.8 5.2 0.67 10.5 1.2 2.5 1 1 1 2 2 2 0 Spectrin repeat Fzo_mitofusin PF04799.13 CBK24341.2 - 0.98 8.9 6.2 0.39 10.3 2.4 2.0 1 1 1 2 2 2 0 fzo-like conserved region DASH_Dad3 PF08656.10 CBK24341.2 - 1.7 8.8 6.6 26 5.0 5.7 3.3 2 1 0 2 2 2 0 DASH complex subunit Dad3 SKA2 PF16740.5 CBK24341.2 - 2.6 7.9 9.3 2.8 7.8 3.4 3.0 1 1 1 2 2 2 0 Spindle and kinetochore-associated protein 2 Spc24 PF08286.11 CBK24341.2 - 2.6 8.3 8.0 2.4e+02 2.0 7.9 2.7 1 1 0 1 1 1 0 Spc24 subunit of Ndc80 Cauli_DNA-bind PF03310.13 CBK24341.2 - 3.1 7.9 6.8 3.8 7.6 1.1 2.6 1 1 2 3 3 3 0 Caulimovirus DNA-binding protein Snapin_Pallidin PF14712.6 CBK24341.2 - 4.2 7.9 8.7 0.66 10.4 2.6 2.6 1 1 2 3 3 3 0 Snapin/Pallidin Ribosomal_L14 PF00238.19 CBK24342.2 - 1.3e-35 122.1 0.0 1.5e-35 121.9 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e Pkinase PF00069.25 CBK24343.2 - 6e-17 61.9 0.0 1.8e-16 60.3 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain APH PF01636.23 CBK24343.2 - 1.2e-06 28.7 0.5 4.4e-06 26.8 0.0 2.0 2 0 0 2 2 2 1 Phosphotransferase enzyme family Pkinase_Tyr PF07714.17 CBK24343.2 - 1.7e-06 27.5 0.0 2.5e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Choline_kinase PF01633.20 CBK24343.2 - 0.0099 15.5 0.0 0.018 14.6 0.0 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase Kinase-like PF14531.6 CBK24343.2 - 0.038 13.3 0.0 0.053 12.8 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Pox_ser-thr_kin PF05445.11 CBK24343.2 - 0.13 11.2 0.3 0.2 10.6 0.3 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase YrbL-PhoP_reg PF10707.9 CBK24343.2 - 0.18 11.3 0.0 0.3 10.6 0.0 1.3 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL EcKinase PF02958.20 CBK24343.2 - 0.18 11.1 0.3 0.28 10.4 0.3 1.2 1 0 0 1 1 1 0 Ecdysteroid kinase DUF1664 PF07889.12 CBK24344.2 - 0.0019 18.2 18.6 0.016 15.2 2.1 3.0 3 0 0 3 3 3 2 Protein of unknown function (DUF1664) PKHD_C PF18331.1 CBK24344.2 - 0.031 14.3 0.9 0.46 10.6 0.1 3.2 3 1 0 3 3 3 0 PKHD-type hydroxylase C-terminal domain YabA PF06156.13 CBK24344.2 - 0.22 12.2 19.4 0.13 12.9 6.6 2.8 1 1 1 2 2 2 0 Initiation control protein YabA CENP-F_leu_zip PF10473.9 CBK24344.2 - 0.23 11.5 25.9 0.097 12.7 10.9 2.2 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 CENP-H PF05837.12 CBK24344.2 - 0.37 11.2 23.2 0.23 11.9 6.8 2.1 2 0 0 2 2 2 0 Centromere protein H (CENP-H) DUF4407 PF14362.6 CBK24344.2 - 0.54 9.6 12.4 0.72 9.2 12.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) KLRAQ PF10205.9 CBK24344.2 - 1.1 9.5 22.5 2.7 8.3 4.3 3.1 1 1 2 3 3 3 0 Predicted coiled-coil domain-containing protein He_PIG PF05345.12 CBK24346.2 - 8.4e-27 93.1 45.6 9.1e-06 25.8 0.9 7.4 7 0 0 7 7 7 6 Putative Ig domain DUF11 PF01345.18 CBK24346.2 - 4.2e-05 23.8 4.0 3.1 8.1 0.4 5.2 4 1 0 4 4 4 2 Domain of unknown function DUF11 I-set PF07679.16 CBK24346.2 - 0.00092 19.2 6.9 7 6.8 0.1 4.6 4 0 0 4 4 4 3 Immunoglobulin I-set domain F5_F8_type_C PF00754.25 CBK24346.2 - 0.018 15.2 28.0 0.1 12.7 0.4 4.5 4 0 0 4 4 4 0 F5/8 type C domain HRM PF02793.22 CBK24346.2 - 0.16 12.3 15.2 0.73 10.2 0.1 5.2 5 0 0 5 5 5 0 Hormone receptor domain DUF3185 PF11381.8 CBK24346.2 - 1.1 9.4 6.4 3.3 7.8 6.4 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3185) PGP_phosphatase PF09419.10 CBK24347.2 - 1.7e-32 112.4 0.0 2.1e-32 112.0 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial PGP phosphatase Hydrolase_like PF13242.6 CBK24347.2 - 1.2e-06 28.4 0.0 1.9e-06 27.8 0.0 1.3 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.26 CBK24347.2 - 1.8e-05 25.1 0.0 0.084 13.2 0.0 2.1 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 CBK24347.2 - 0.021 14.9 0.0 0.1 12.7 0.0 2.0 1 1 0 2 2 2 0 Haloacid dehalogenase-like hydrolase ANAPC4_WD40 PF12894.7 CBK24349.2 - 0.00023 21.4 0.0 0.18 12.1 0.0 2.1 2 0 0 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 CBK24349.2 - 0.0003 21.5 0.0 2 9.4 0.0 3.2 3 0 0 3 3 3 2 WD domain, G-beta repeat A_deaminase PF00962.22 CBK24350.2 - 7.2e-20 71.6 0.0 9.3e-19 67.9 0.0 1.9 1 1 0 1 1 1 1 Adenosine/AMP deaminase Pkinase PF00069.25 CBK24351.2 - 5.4e-40 137.4 0.0 6.2e-40 137.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBK24351.2 - 2.3e-27 95.9 0.0 2.6e-27 95.7 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CBK24351.2 - 0.0086 14.9 0.0 0.011 14.5 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 CBK24351.2 - 0.044 13.1 0.1 0.17 11.2 0.1 1.7 1 1 0 1 1 1 0 Kinase-like YrbL-PhoP_reg PF10707.9 CBK24351.2 - 0.059 12.9 0.0 0.093 12.2 0.0 1.3 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL FTA2 PF13095.6 CBK24351.2 - 0.081 12.5 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 G6PD_C PF02781.16 CBK24352.2 - 4.4e-111 370.7 0.0 5.7e-111 370.4 0.0 1.1 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.22 CBK24352.2 - 9e-57 192.6 0.0 1.4e-56 192.0 0.0 1.3 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, NAD binding domain CASP_C PF08172.12 CBK24353.2 - 5.1e-06 26.0 6.6 5.1e-06 26.0 6.6 2.6 2 1 0 2 2 2 1 CASP C terminal Filament PF00038.21 CBK24353.2 - 2.8e-05 23.8 20.6 0.011 15.4 3.2 3.1 2 1 1 3 3 3 3 Intermediate filament protein DUF4407 PF14362.6 CBK24353.2 - 0.00093 18.6 16.3 0.0012 18.3 2.6 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4407) FAM184 PF15665.5 CBK24353.2 - 0.0026 17.6 5.3 0.0026 17.6 5.3 2.7 2 1 0 2 2 2 1 Family with sequence similarity 184, A and B DUF724 PF05266.14 CBK24353.2 - 0.045 13.6 15.2 0.12 12.2 0.5 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF724) Leu_zip PF15294.6 CBK24353.2 - 0.1 12.1 17.5 0.16 11.4 6.3 2.5 2 1 1 3 3 3 0 Leucine zipper DUF2046 PF09755.9 CBK24353.2 - 0.11 11.8 17.2 2.5 7.3 17.6 2.7 1 1 0 1 1 1 0 Uncharacterized conserved protein H4 (DUF2046) TPR_MLP1_2 PF07926.12 CBK24353.2 - 0.14 12.2 25.1 2.4 8.2 1.8 3.6 3 1 0 3 3 3 0 TPR/MLP1/MLP2-like protein CTNNBL PF08216.11 CBK24353.2 - 0.15 12.3 2.6 0.69 10.1 0.1 2.7 2 0 0 2 2 2 0 Catenin-beta-like, Arm-motif containing nuclear DUF4200 PF13863.6 CBK24353.2 - 0.15 12.5 19.2 0.3 11.5 3.6 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4200) Occludin_ELL PF07303.13 CBK24353.2 - 0.19 12.5 13.1 2.5 8.9 0.4 3.4 3 1 1 4 4 4 0 Occludin homology domain PspA_IM30 PF04012.12 CBK24353.2 - 0.19 11.3 23.8 0.24 11.0 8.0 3.3 2 1 1 3 3 3 0 PspA/IM30 family TAF6_C PF07571.13 CBK24353.2 - 0.19 12.1 0.9 1.1 9.6 0.3 2.4 2 0 0 2 2 2 0 TAF6 C-terminal HEAT repeat domain ADIP PF11559.8 CBK24353.2 - 0.2 11.8 24.1 0.24 11.4 3.6 3.2 3 0 0 3 3 3 0 Afadin- and alpha -actinin-Binding Tup_N PF08581.10 CBK24353.2 - 0.25 11.6 20.1 0.85 10.0 1.9 3.5 3 0 0 3 3 3 0 Tup N-terminal Tropomyosin_1 PF12718.7 CBK24353.2 - 0.32 11.2 19.7 1.6 8.9 7.1 2.7 2 1 0 2 2 2 0 Tropomyosin like Coat_F PF07875.12 CBK24353.2 - 0.32 11.2 4.1 1.1 9.6 0.1 2.9 3 0 0 3 3 2 0 Coat F domain Apolipoprotein PF01442.18 CBK24353.2 - 0.38 10.6 21.5 0.13 12.2 6.7 2.5 2 1 0 2 2 2 0 Apolipoprotein A1/A4/E domain DUF1664 PF07889.12 CBK24353.2 - 0.49 10.4 10.4 8.5 6.4 0.4 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) Atg14 PF10186.9 CBK24353.2 - 0.51 9.4 20.3 0.49 9.4 2.8 2.7 2 1 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 Ax_dynein_light PF10211.9 CBK24353.2 - 0.52 10.2 19.4 0.8 9.6 2.9 3.4 2 1 0 2 2 2 0 Axonemal dynein light chain PCRF PF03462.18 CBK24353.2 - 0.65 9.8 17.1 0.29 11.0 2.9 3.2 2 1 1 3 3 3 0 PCRF domain CtIP_N PF10482.9 CBK24353.2 - 0.83 9.7 14.2 1.3 9.1 0.1 3.6 3 1 0 3 3 3 0 Tumour-suppressor protein CtIP N-terminal domain Fib_alpha PF08702.10 CBK24353.2 - 0.84 9.8 17.2 1.7 8.8 1.5 3.2 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family Fez1 PF06818.15 CBK24353.2 - 0.88 10.0 20.4 5 7.5 3.4 2.8 2 1 0 2 2 2 0 Fez1 CENP-Q PF13094.6 CBK24353.2 - 1.1 9.5 20.6 0.21 11.8 0.3 3.6 3 1 1 4 4 4 0 CENP-Q, a CENPA-CAD centromere complex subunit APG6_N PF17675.1 CBK24353.2 - 1.2 9.6 30.0 0.86 10.1 8.2 3.5 3 1 0 3 3 3 0 Apg6 coiled-coil region MscS_porin PF12795.7 CBK24353.2 - 1.5 8.3 23.5 1.2 8.7 9.5 3.1 3 0 0 3 3 3 0 Mechanosensitive ion channel porin domain Troponin PF00992.20 CBK24353.2 - 1.6 9.0 19.2 0.51 10.6 1.6 3.3 3 0 0 3 3 3 0 Troponin Syntaxin-6_N PF09177.11 CBK24353.2 - 1.8 9.2 14.7 1.1 9.8 1.8 3.3 2 2 1 3 3 3 0 Syntaxin 6, N-terminal ATG16 PF08614.11 CBK24353.2 - 2 8.6 24.9 0.21 11.8 2.6 3.5 3 1 0 3 3 3 0 Autophagy protein 16 (ATG16) DUF4618 PF15397.6 CBK24353.2 - 2 7.7 12.5 3.8 6.8 1.0 3.4 3 1 0 4 4 4 0 Domain of unknown function (DUF4618) DUF4763 PF15960.5 CBK24353.2 - 2.1 7.6 11.6 0.78 9.0 1.7 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4763) HalX PF08663.10 CBK24353.2 - 2.1 8.7 25.0 0.1 12.9 7.6 3.8 3 1 0 3 3 3 0 HalX domain TMPIT PF07851.13 CBK24353.2 - 3.2 6.9 12.0 4.7 6.4 0.5 2.6 2 1 1 3 3 3 0 TMPIT-like protein MIP-T3_C PF17749.1 CBK24353.2 - 3.7 7.5 15.0 3.4 7.6 0.5 3.6 3 1 0 3 3 3 0 Microtubule-binding protein MIP-T3 C-terminal region DUF2407_C PF13373.6 CBK24353.2 - 3.8 7.7 6.2 2 8.6 1.8 2.5 2 1 1 3 3 3 0 DUF2407 C-terminal domain AAA_13 PF13166.6 CBK24353.2 - 4.3 5.8 18.1 0.72 8.4 2.0 2.9 2 1 1 3 3 3 0 AAA domain Spc7 PF08317.11 CBK24353.2 - 4.7 6.0 23.7 1.3 7.8 5.9 2.9 2 1 1 3 3 3 0 Spc7 kinetochore protein FlaC_arch PF05377.11 CBK24353.2 - 4.8 7.7 13.1 30 5.1 0.1 5.2 4 2 1 5 5 5 0 Flagella accessory protein C (FlaC) YlqD PF11068.8 CBK24353.2 - 5.6 7.3 13.3 1.4e+02 2.8 10.3 3.1 1 1 1 2 2 2 0 YlqD protein BST2 PF16716.5 CBK24353.2 - 5.7 7.6 15.0 22 5.7 2.7 3.7 2 2 0 2 2 2 0 Bone marrow stromal antigen 2 bZIP_1 PF00170.21 CBK24353.2 - 6.8 6.9 22.2 13 6.0 0.1 4.5 3 2 1 5 5 5 0 bZIP transcription factor Atg14 PF10186.9 CBK24354.2 - 0.00062 18.9 13.8 0.00062 18.9 13.8 2.0 1 1 1 2 2 2 1 Vacuolar sorting 38 and autophagy-related subunit 14 Spc7 PF08317.11 CBK24354.2 - 0.0034 16.3 12.6 0.0034 16.3 12.6 2.1 1 1 1 2 2 2 1 Spc7 kinetochore protein AKNA PF12443.8 CBK24354.2 - 0.0039 17.8 6.3 0.0039 17.8 6.3 2.1 2 1 0 2 2 2 1 AT-hook-containing transcription factor FapA PF03961.13 CBK24354.2 - 0.0059 15.3 10.4 0.0076 14.9 10.4 1.1 1 0 0 1 1 1 1 Flagellar Assembly Protein A GAS PF13851.6 CBK24354.2 - 0.016 14.6 19.6 0.47 9.8 12.0 3.0 2 1 1 3 3 3 0 Growth-arrest specific micro-tubule binding DUF4164 PF13747.6 CBK24354.2 - 0.018 15.3 8.4 0.018 15.3 8.4 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4164) Seryl_tRNA_N PF02403.22 CBK24354.2 - 0.022 15.0 5.9 0.022 15.0 5.9 2.4 2 1 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DUF3209 PF11483.8 CBK24354.2 - 0.04 14.4 1.6 0.04 14.4 1.6 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3209) Cortex-I_coil PF09304.10 CBK24354.2 - 0.056 13.7 0.3 0.056 13.7 0.3 2.6 2 1 0 2 2 2 0 Cortexillin I, coiled coil KASH_CCD PF14662.6 CBK24354.2 - 0.11 12.3 25.2 0.013 15.3 16.8 2.2 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 or KASH YabA PF06156.13 CBK24354.2 - 0.13 12.9 18.2 1.1 10.0 4.9 3.1 1 1 2 3 3 3 0 Initiation control protein YabA Tox-REase-5 PF15648.6 CBK24354.2 - 0.14 12.6 0.6 0.26 11.8 0.1 1.7 2 0 0 2 2 1 0 Restriction endonuclease fold toxin 5 HemX PF04375.14 CBK24354.2 - 0.18 11.0 13.6 0.3 10.3 9.1 2.2 1 1 0 2 2 2 0 HemX, putative uroporphyrinogen-III C-methyltransferase SHE3 PF17078.5 CBK24354.2 - 0.22 11.2 23.1 0.043 13.5 14.0 2.3 1 1 1 2 2 2 0 SWI5-dependent HO expression protein 3 FliT PF05400.13 CBK24354.2 - 0.43 11.4 10.5 0.36 11.7 7.0 2.4 2 1 0 2 2 2 0 Flagellar protein FliT ARD PF03079.14 CBK24354.2 - 0.6 10.3 3.9 0.28 11.4 0.6 1.9 2 0 0 2 2 2 0 ARD/ARD' family DUF4055 PF13264.6 CBK24354.2 - 0.83 9.8 5.0 0.42 10.8 2.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4055) DUF641 PF04859.12 CBK24354.2 - 1.1 9.6 15.6 0.18 12.2 8.4 2.3 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) DUF5082 PF16888.5 CBK24354.2 - 1.3 9.4 14.2 0.051 13.8 5.0 2.9 1 1 1 2 2 2 0 Domain of unknown function (DUF5082) bZIP_1 PF00170.21 CBK24354.2 - 1.3 9.2 18.8 0.25 11.5 1.5 4.4 3 1 2 5 5 5 0 bZIP transcription factor HALZ PF02183.18 CBK24354.2 - 1.3 9.3 11.3 0.85 9.9 0.4 3.8 2 1 1 3 3 3 0 Homeobox associated leucine zipper Cnn_1N PF07989.11 CBK24354.2 - 1.4 9.1 20.2 0.93 9.7 6.1 4.3 3 1 2 5 5 4 0 Centrosomin N-terminal motif 1 Med9 PF07544.13 CBK24354.2 - 1.4 9.0 12.7 10 6.3 4.5 3.4 2 1 1 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 ADIP PF11559.8 CBK24354.2 - 1.5 8.9 17.8 0.062 13.4 10.0 2.3 1 1 0 2 2 2 0 Afadin- and alpha -actinin-Binding DUF724 PF05266.14 CBK24354.2 - 1.7 8.4 18.3 0.042 13.7 9.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF724) DUF4208 PF13907.6 CBK24354.2 - 2 8.9 12.7 1.7 9.1 1.1 3.0 2 2 0 2 2 2 0 Domain of unknown function (DUF4208) Fez1 PF06818.15 CBK24354.2 - 2.1 8.8 20.8 0.43 11.0 12.1 2.1 1 1 1 2 2 2 0 Fez1 UPF0449 PF15136.6 CBK24354.2 - 2.8 8.5 14.1 1.6 9.2 2.6 3.3 1 1 2 3 3 3 0 Uncharacterised protein family UPF0449 DUF3450 PF11932.8 CBK24354.2 - 2.9 7.1 17.6 0.38 10.0 10.5 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) bZIP_2 PF07716.15 CBK24354.2 - 3 8.0 10.7 1.4 9.0 1.3 3.6 2 1 0 3 3 3 0 Basic region leucine zipper DUF4407 PF14362.6 CBK24354.2 - 3.2 7.0 8.8 12 5.1 8.8 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) ZapB PF06005.12 CBK24354.2 - 3.4 8.2 19.9 0.2 12.2 3.5 3.5 2 1 1 3 3 3 0 Cell division protein ZapB APG6_N PF17675.1 CBK24354.2 - 4.7 7.8 25.3 2.6 8.6 16.9 2.6 1 1 1 2 2 2 0 Apg6 coiled-coil region DUF2203 PF09969.9 CBK24354.2 - 5.1 7.8 10.8 6 7.6 4.1 2.3 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) DivIC PF04977.15 CBK24354.2 - 5.6 6.8 15.5 1.1 9.1 5.9 3.7 2 1 1 4 4 4 0 Septum formation initiator UPF0242 PF06785.11 CBK24354.2 - 5.7 7.0 20.9 7.6 6.6 3.2 2.4 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus SHQ1 PF04925.15 CBK24355.2 - 8.2e-52 175.3 3.1 9.7e-52 175.1 3.1 1.0 1 0 0 1 1 1 1 SHQ1 protein PIH1_CS PF18201.1 CBK24356.2 - 0.1 13.0 0.0 0.13 12.7 0.0 1.2 1 0 0 1 1 1 0 PIH1 CS-like domain zf-HIT PF04438.16 CBK24357.2 - 2.3e-09 37.0 1.6 2.3e-09 37.0 1.6 2.6 3 0 0 3 3 3 1 HIT zinc finger zf-CCHC PF00098.23 CBK24357.2 - 0.0051 16.8 0.8 0.0051 16.8 0.8 2.1 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC_5 PF14787.6 CBK24357.2 - 0.015 15.0 1.2 0.015 15.0 1.2 2.3 2 0 0 2 2 2 0 GAG-polyprotein viral zinc-finger DUF4404 PF14357.6 CBK24357.2 - 0.049 14.3 1.6 0.095 13.4 1.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4404) Prominin PF05478.11 CBK24357.2 - 0.2 9.6 0.8 0.26 9.2 0.8 1.1 1 0 0 1 1 1 0 Prominin CLIP1_ZNF PF16641.5 CBK24357.2 - 0.26 11.2 3.2 1.6 8.7 0.3 2.5 2 0 0 2 2 2 0 CLIP1 zinc knuckle zf-CCHC_4 PF14392.6 CBK24357.2 - 1.5 8.6 6.9 2.8 7.7 1.3 2.5 2 0 0 2 2 2 0 Zinc knuckle PI3_PI4_kinase PF00454.27 CBK24359.2 - 1.3e-64 218.4 1.3 3.4e-64 217.0 0.3 2.2 2 0 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase FAT PF02259.23 CBK24359.2 - 1.8e-43 149.1 3.0 2e-43 149.0 0.8 2.2 2 0 0 2 2 2 1 FAT domain FRB_dom PF08771.11 CBK24359.2 - 8.4e-24 83.9 5.9 1.4e-23 83.2 2.4 3.3 3 0 0 3 3 2 1 FKBP12-rapamycin binding domain DUF3385 PF11865.8 CBK24359.2 - 6.2e-23 81.5 0.0 6.2e-23 81.5 0.0 5.2 5 1 0 5 5 5 1 Domain of unknown function (DUF3385) FATC PF02260.20 CBK24359.2 - 1.1e-09 37.9 0.3 1.1e-09 37.9 0.3 2.0 2 0 0 2 2 2 1 FATC domain HEAT PF02985.22 CBK24359.2 - 8.1e-05 22.6 8.6 0.12 12.8 0.1 7.4 7 0 0 7 7 7 1 HEAT repeat MOR2-PAG1_C PF14225.6 CBK24359.2 - 0.0023 17.9 2.6 1.2 8.9 0.2 3.7 2 1 0 2 2 2 2 Cell morphogenesis C-terminal TPR_19 PF14559.6 CBK24359.2 - 0.0058 17.1 0.5 2.2 8.9 0.1 4.0 3 0 0 3 3 3 1 Tetratricopeptide repeat SpoOE-like PF09388.10 CBK24359.2 - 0.079 12.9 5.2 6.8 6.7 0.4 3.4 2 0 0 2 2 2 0 Spo0E like sporulation regulatory protein TPR_7 PF13176.6 CBK24359.2 - 0.23 11.6 3.8 0.58 10.3 0.1 3.7 5 0 0 5 5 3 0 Tetratricopeptide repeat BTAD PF03704.17 CBK24359.2 - 0.64 10.4 3.6 11 6.4 0.7 2.9 2 0 0 2 2 2 0 Bacterial transcriptional activator domain RTP1_C1 PF10363.9 CBK24359.2 - 1.1 9.5 9.7 13 6.0 0.1 5.9 6 1 0 6 6 6 0 Required for nuclear transport of RNA pol II C-terminus 1 GTP_cyclohydroI PF01227.22 CBK24360.2 - 3.6e-55 186.1 0.0 4.1e-55 186.0 0.0 1.0 1 0 0 1 1 1 1 GTP cyclohydrolase I QueF PF14489.6 CBK24360.2 - 0.015 15.4 0.0 0.031 14.4 0.0 1.5 1 0 0 1 1 1 0 QueF-like protein Ribosomal_S2 PF00318.20 CBK24361.2 - 4.5e-30 104.5 1.3 9.5e-15 54.4 0.1 2.2 1 1 1 2 2 2 2 Ribosomal protein S2 40S_SA_C PF16122.5 CBK24361.2 - 0.028 15.8 5.3 0.056 14.8 5.3 1.5 1 0 0 1 1 1 0 40S ribosomal protein SA C-terminus RRM_1 PF00076.22 CBK24362.2 - 8.2e-36 121.7 0.0 1.5e-16 60.0 0.0 2.1 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CBK24362.2 - 4.7e-08 33.1 0.0 0.0027 17.8 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif RRM_5 PF13893.6 CBK24362.2 - 5.8e-05 22.7 0.0 0.0067 16.0 0.0 2.7 1 1 1 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) EMC1_C PF07774.13 CBK24362.2 - 0.0094 15.6 0.0 0.017 14.8 0.0 1.3 1 0 0 1 1 1 1 ER membrane protein complex subunit 1, C-terminal Coatomer_WDAD PF04053.14 CBK24364.2 - 5e-93 312.6 0.0 8.6e-93 311.8 0.0 1.3 1 0 0 1 1 1 1 Coatomer WD associated region COPI_C PF06957.11 CBK24364.2 - 1.1e-76 258.2 0.0 1.6e-76 257.7 0.0 1.2 1 0 0 1 1 1 1 Coatomer (COPI) alpha subunit C-terminus WD40 PF00400.32 CBK24364.2 - 4.4e-47 157.1 16.5 1.1e-07 32.4 0.0 7.9 8 0 0 8 8 8 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBK24364.2 - 1.8e-11 44.2 1.7 0.0024 18.1 0.0 6.1 3 2 3 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain zinc_ribbon_4 PF13717.6 CBK24364.2 - 0.023 14.6 0.1 0.065 13.2 0.1 1.8 1 0 0 1 1 1 0 zinc-ribbon domain Nup160 PF11715.8 CBK24364.2 - 1.1 7.8 5.1 1.5 7.4 0.0 3.1 2 1 2 4 4 4 0 Nucleoporin Nup120/160 TPR_4 PF07721.14 CBK24364.2 - 4 8.3 8.8 0.59 10.9 0.2 4.1 3 0 0 3 3 3 0 Tetratricopeptide repeat Ras PF00071.22 CBK24365.2 - 3.8e-49 166.4 0.0 4.6e-49 166.1 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CBK24365.2 - 1.2e-29 103.0 0.0 1.8e-29 102.4 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CBK24365.2 - 4.5e-12 45.8 0.0 5.5e-12 45.5 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 CBK24365.2 - 0.00071 19.2 0.0 0.0018 17.8 0.0 1.6 1 1 0 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 CBK24365.2 - 0.0048 17.0 0.0 0.0069 16.5 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 CBK24365.2 - 0.03 14.2 0.0 3.4 7.5 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase ATP_bind_1 PF03029.17 CBK24365.2 - 0.083 12.7 0.1 11 5.8 0.1 2.1 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein G-alpha PF00503.20 CBK24365.2 - 0.1 11.8 0.2 12 4.9 0.0 2.2 2 1 0 2 2 2 0 G-protein alpha subunit Septin PF00735.18 CBK24365.2 - 0.17 11.1 0.0 0.3 10.3 0.0 1.4 1 0 0 1 1 1 0 Septin AAA_7 PF12775.7 CBK24365.2 - 0.18 11.3 0.1 0.3 10.6 0.1 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region tRNA-synt_2 PF00152.20 CBK24366.2 - 1.7e-74 250.7 0.0 2.2e-74 250.4 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 CBK24366.2 - 1.9e-11 43.7 0.0 4.6e-11 42.6 0.0 1.7 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 CBK24366.2 - 2e-08 34.0 0.2 0.002 17.7 0.1 2.2 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) U-box PF04564.15 CBK24368.2 - 0.0029 17.7 0.0 0.0059 16.8 0.0 1.5 1 0 0 1 1 1 1 U-box domain Myb_DNA-binding PF00249.31 CBK24368.2 - 0.0039 17.4 0.0 0.01 16.0 0.0 1.8 2 0 0 2 2 2 1 Myb-like DNA-binding domain CH PF00307.31 CBK24369.2 - 9.5e-11 41.8 0.2 1.1e-10 41.6 0.2 1.1 1 0 0 1 1 1 1 Calponin homology (CH) domain RFX_DNA_binding PF02257.15 CBK24369.2 - 0.09 13.4 0.0 2.7 8.7 0.0 2.5 2 1 0 2 2 2 0 RFX DNA-binding domain DIX PF00778.17 CBK24370.2 - 5.1e-20 71.1 0.2 7.3e-20 70.6 0.2 1.2 1 0 0 1 1 1 1 DIX domain DUF966 PF06136.13 CBK24370.2 - 0.00048 20.0 0.0 0.00061 19.6 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF966) Codanin-1_C PF15296.6 CBK24370.2 - 0.098 12.7 0.1 0.15 12.1 0.1 1.2 1 0 0 1 1 1 0 Codanin-1 C-terminus Acatn PF13000.7 CBK24371.2 - 1.3e-53 182.4 0.0 4.7e-53 180.5 0.0 1.7 1 1 0 1 1 1 1 Acetyl-coenzyme A transporter 1 OAD_gamma PF04277.13 CBK24371.2 - 0.18 12.4 0.2 0.63 10.7 0.0 2.0 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain Sugar_tr PF00083.24 CBK24371.2 - 1 8.1 9.6 2.5 6.9 9.6 1.5 1 1 0 1 1 1 0 Sugar (and other) transporter Ribosomal_L19 PF01245.20 CBK24372.2 - 2.5e-18 66.0 0.1 3.7e-18 65.5 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L19 TMF_TATA_bd PF12325.8 CBK24373.2 - 6.1e-06 26.4 13.7 6.1e-06 26.4 13.7 2.1 2 0 0 2 2 2 1 TATA element modulatory factor 1 TATA binding PKcGMP_CC PF16808.5 CBK24373.2 - 0.0016 18.3 0.8 0.0016 18.3 0.8 3.1 4 0 0 4 4 4 1 Coiled-coil N-terminus of cGMP-dependent protein kinase XLF PF09302.11 CBK24373.2 - 0.0017 18.5 0.0 0.0017 18.5 0.0 2.8 1 1 1 3 3 3 1 XLF-Cernunnos, XRcc4-like factor, NHEJ component Macoilin PF09726.9 CBK24373.2 - 0.0031 16.2 21.7 0.0038 15.9 21.7 1.1 1 0 0 1 1 1 1 Macoilin family DUF724 PF05266.14 CBK24373.2 - 0.015 15.2 4.2 0.015 15.2 4.2 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF724) FAM76 PF16046.5 CBK24373.2 - 0.017 14.5 17.3 0.022 14.1 17.3 1.2 1 0 0 1 1 1 0 FAM76 protein Cep57_MT_bd PF06657.13 CBK24373.2 - 0.057 13.9 1.1 0.057 13.9 1.1 3.5 2 1 1 3 3 3 0 Centrosome microtubule-binding domain of Cep57 Csm2_III-A PF03750.13 CBK24373.2 - 0.058 14.2 3.1 0.23 12.3 3.2 2.0 1 1 0 1 1 1 0 Csm2 Type III-A DUF4047 PF13256.6 CBK24373.2 - 0.096 12.9 4.2 0.19 11.9 1.6 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4047) Rx_N PF18052.1 CBK24373.2 - 0.18 12.1 6.9 0.48 10.7 6.8 1.9 1 1 0 1 1 1 0 Rx N-terminal domain DUF1664 PF07889.12 CBK24373.2 - 7.7 6.6 14.3 2.2 8.3 0.5 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) CPSF73-100_C PF11718.8 CBK24374.2 - 1.7e-31 109.4 2.6 2.7e-31 108.8 2.6 1.3 1 0 0 1 1 1 1 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term Beta-Casp PF10996.8 CBK24374.2 - 6.5e-23 81.1 0.0 1.5e-22 80.0 0.0 1.7 1 0 0 1 1 1 1 Beta-Casp domain Lactamase_B_6 PF16661.5 CBK24374.2 - 4.2e-16 58.9 0.0 2e-15 56.7 0.0 2.1 3 0 0 3 3 3 1 Metallo-beta-lactamase superfamily domain RMMBL PF07521.12 CBK24374.2 - 1.2e-15 57.2 0.0 3e-15 55.9 0.0 1.8 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain Lactamase_B PF00753.27 CBK24374.2 - 4.2e-11 43.2 0.1 4e-08 33.5 0.1 2.5 2 0 0 2 2 2 2 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 CBK24374.2 - 4.5e-08 32.8 0.1 3.8e-07 29.8 0.0 2.5 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Beta_lactamase3 PF17030.5 CBK24374.2 - 6.6e-05 22.2 0.0 0.00014 21.2 0.0 1.4 1 0 0 1 1 1 1 Putative beta-lactamase-like family Lactamase_B_3 PF13483.6 CBK24374.2 - 0.0067 16.3 0.0 0.023 14.6 0.0 2.0 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Ribosomal_L26 PF16906.5 CBK24376.2 - 1.5e-19 70.2 0.6 2e-19 69.9 0.6 1.2 1 0 0 1 1 1 1 Ribosomal proteins L26 eukaryotic, L24P archaeal KOW PF00467.29 CBK24376.2 - 9.6e-10 38.1 3.0 1.9e-09 37.1 3.0 1.7 1 1 0 1 1 1 1 KOW motif tRNA-synt_2 PF00152.20 CBK24377.2 - 3.1e-78 263.0 0.0 4.2e-78 262.6 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 CBK24377.2 - 1.9e-11 43.8 0.1 5.8e-11 42.2 0.1 1.8 2 0 0 2 2 2 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 CBK24377.2 - 0.031 13.8 0.2 0.4 10.1 0.0 2.5 3 0 0 3 3 3 0 tRNA synthetases class II core domain (F) tRNA-synt_2b PF00587.25 CBK24377.2 - 0.072 13.0 0.1 0.26 11.2 0.1 2.0 1 1 0 1 1 1 0 tRNA synthetase class II core domain (G, H, P, S and T) Complex1_51K PF01512.17 CBK24378.2 - 7.3e-43 146.1 0.0 1.2e-42 145.4 0.0 1.2 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase 51 Kd subunit NADH_4Fe-4S PF10589.9 CBK24378.2 - 7.8e-25 86.8 0.1 1.9e-24 85.5 0.1 1.6 2 0 0 2 2 2 1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region SLBB PF10531.9 CBK24378.2 - 4.2e-07 29.7 0.0 8.9e-07 28.7 0.0 1.6 1 0 0 1 1 1 1 SLBB domain Tubulin PF00091.25 CBK24379.2 - 5.6e-69 232.3 0.1 1.1e-68 231.4 0.1 1.5 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 CBK24379.2 - 1.4e-38 131.9 0.0 2.3e-38 131.2 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 CBK24379.2 - 1.2e-07 32.0 0.0 2.7e-07 30.9 0.0 1.6 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_2 PF13809.6 CBK24379.2 - 0.016 14.4 0.1 0.064 12.4 0.0 1.9 2 0 0 2 2 2 0 Tubulin like Tubulin_3 PF14881.6 CBK24379.2 - 0.029 14.0 0.0 0.06 13.0 0.0 1.5 1 0 0 1 1 1 0 Tubulin domain DUF1681 PF07933.14 CBK24380.2 - 1.6e-47 160.9 0.0 2.2e-47 160.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1681) SWIRM-assoc_2 PF16496.5 CBK24380.2 - 0.0069 15.3 3.0 0.0085 15.0 3.0 1.1 1 0 0 1 1 1 1 SWIRM-associated domain at the N-terminal CDC45 PF02724.14 CBK24380.2 - 0.13 10.6 3.6 0.14 10.4 3.6 1.0 1 0 0 1 1 1 0 CDC45-like protein Utp12 PF04003.12 CBK24381.2 - 2.7e-07 30.8 0.1 3.4e-07 30.5 0.1 1.2 1 0 0 1 1 1 1 Dip2/Utp12 Family MMR_HSR1 PF01926.23 CBK24382.2 - 1.1e-12 48.0 0.5 1.9e-11 44.0 0.0 2.8 3 0 0 3 3 3 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 CBK24382.2 - 4.6e-07 29.9 0.0 0.00033 20.6 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase PT PF04886.12 CBK24382.2 - 0.00054 19.4 20.8 0.066 12.8 6.9 2.4 2 0 0 2 2 2 2 PT repeat FeoB_N PF02421.18 CBK24382.2 - 0.0019 17.8 0.1 0.0094 15.5 0.1 2.0 2 0 0 2 2 2 1 Ferrous iron transport protein B cobW PF02492.19 CBK24382.2 - 0.024 14.2 0.1 0.86 9.2 0.0 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain MeaB PF03308.16 CBK24382.2 - 0.04 12.9 0.0 0.091 11.7 0.0 1.5 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB IstB_IS21 PF01695.17 CBK24382.2 - 0.1 12.3 0.0 0.16 11.7 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein ABC_tran PF00005.27 CBK24382.2 - 0.34 11.4 0.0 0.34 11.4 0.0 2.1 2 0 0 2 2 2 0 ABC transporter Nop14 PF04147.12 CBK24382.2 - 1.8 6.7 21.9 2.8 6.0 21.9 1.2 1 0 0 1 1 1 0 Nop14-like family PNISR PF15996.5 CBK24382.2 - 1.8 8.8 31.0 0.068 13.4 24.0 2.1 2 0 0 2 2 2 0 Arginine/serine-rich protein PNISR TFIIF_alpha PF05793.12 CBK24382.2 - 4.6 5.7 31.0 0.035 12.7 23.0 1.4 2 0 0 2 2 2 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) CDC45 PF02724.14 CBK24382.2 - 6.9 4.8 15.3 14 3.9 15.3 1.5 1 0 0 1 1 1 0 CDC45-like protein RAB3GAP2_C PF14656.6 CBK24382.2 - 8 4.6 6.6 14 3.7 6.6 1.3 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit C-terminus EF-hand_1 PF00036.32 CBK24383.2 - 9.7e-23 78.0 23.4 2.4e-06 26.7 0.2 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 CBK24383.2 - 4.2e-22 78.4 11.3 1.7e-12 47.6 0.4 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 CBK24383.2 - 1.5e-18 66.3 12.7 1.5e-10 40.8 0.3 3.6 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.6 CBK24383.2 - 1.3e-15 55.9 14.5 1.3e-05 24.8 0.3 4.3 3 1 1 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 CBK24383.2 - 7.5e-13 47.3 18.0 0.00047 19.5 0.1 4.4 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.6 CBK24383.2 - 7.2e-09 35.8 0.3 0.00075 19.8 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain SPARC_Ca_bdg PF10591.9 CBK24383.2 - 0.00014 22.1 1.2 0.41 11.0 0.0 2.4 2 1 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 CBK24383.2 - 0.00056 19.8 5.9 0.55 10.2 0.6 3.1 1 1 1 3 3 3 2 Cytoskeletal-regulatory complex EF hand DUF2789 PF10982.8 CBK24383.2 - 0.0023 18.1 0.0 2.3 8.5 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF2789) DUF5580 PF17743.1 CBK24383.2 - 0.015 13.9 0.0 0.092 11.3 0.0 1.8 1 1 1 2 2 2 0 Family of unknown function (DUF5580) SurA_N_2 PF13623.6 CBK24383.2 - 0.022 14.6 0.0 0.11 12.4 0.0 1.9 1 1 1 2 2 2 0 SurA N-terminal domain EF-hand_14 PF17959.1 CBK24383.2 - 0.032 14.6 0.7 7.4 7.0 0.2 2.4 1 1 1 2 2 2 0 EF-hand domain Dockerin_1 PF00404.18 CBK24383.2 - 0.039 14.1 3.1 1.7 8.9 0.1 2.8 2 1 1 3 3 3 0 Dockerin type I domain Rep_2 PF01719.17 CBK24383.2 - 0.044 13.6 1.0 0.097 12.4 0.4 1.7 1 1 0 2 2 2 0 Plasmid replication protein SurA_N_3 PF13624.6 CBK24383.2 - 0.08 12.7 0.1 0.27 11.0 0.0 1.7 1 1 1 2 2 2 0 SurA N-terminal domain CxC7 PF18866.1 CBK24383.2 - 0.095 12.9 0.0 0.17 12.0 0.0 1.4 1 0 0 1 1 1 0 CxC7 like cysteine cluster associated with KDZ transposases PhetRS_B1 PF18262.1 CBK24383.2 - 0.11 12.8 0.5 1.7 8.9 0.3 2.5 2 1 0 2 2 2 0 Phe-tRNA synthetase beta subunit B1 domain EF-hand_10 PF14788.6 CBK24383.2 - 0.2 11.5 0.1 0.2 11.5 0.1 3.7 3 2 1 4 4 4 0 EF hand SecE PF00584.20 CBK24384.2 - 7.6e-16 57.8 0.0 8.5e-16 57.6 0.0 1.0 1 0 0 1 1 1 1 SecE/Sec61-gamma subunits of protein translocation complex WD40 PF00400.32 CBK24385.2 - 5.6e-47 156.8 18.2 1.2e-10 41.8 0.1 7.2 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBK24385.2 - 4.1e-10 39.8 4.5 0.0063 16.8 0.0 5.5 2 2 4 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 CBK24385.2 - 1.3e-06 27.4 6.9 0.015 14.0 0.1 5.0 3 1 1 5 5 5 3 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 CBK24385.2 - 8.3e-06 25.0 0.3 0.04 12.9 0.0 3.6 2 1 2 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein PQQ_2 PF13360.6 CBK24385.2 - 0.0064 16.1 1.7 0.083 12.5 0.0 2.3 2 1 0 2 2 2 1 PQQ-like domain DUF1513 PF07433.11 CBK24385.2 - 0.0094 15.1 0.3 0.97 8.4 0.1 3.0 1 1 3 4 4 4 1 Protein of unknown function (DUF1513) Cytochrom_D1 PF02239.16 CBK24385.2 - 0.02 13.5 0.0 0.94 7.9 0.0 2.9 2 2 1 3 3 3 0 Cytochrome D1 heme domain PQQ_3 PF13570.6 CBK24385.2 - 0.075 13.5 0.7 18 6.0 0.1 3.8 3 1 0 3 3 3 0 PQQ-like domain SRP68 PF16969.5 CBK24386.2 - 1.3e-29 103.7 0.0 1.7e-29 103.3 0.0 1.1 1 0 0 1 1 1 1 RNA-binding signal recognition particle 68 Cas9_Topo PF17894.1 CBK24386.2 - 0.085 12.9 0.4 0.66 10.1 0.0 2.7 3 0 0 3 3 3 0 Topo homolgy domain in CRISPR-associated endonuclease Cas9 CorA PF01544.18 CBK24386.2 - 0.1 11.9 4.1 0.084 12.2 1.1 2.0 1 1 1 2 2 2 0 CorA-like Mg2+ transporter protein Syja_N PF02383.18 CBK24387.2 - 5.8e-69 232.8 0.0 7.8e-69 232.4 0.0 1.1 1 0 0 1 1 1 1 SacI homology domain HEAT PF02985.22 CBK24388.2 - 5.6e-23 79.0 1.6 1.4e-05 24.9 0.0 5.3 5 0 0 5 5 5 4 HEAT repeat HEAT_2 PF13646.6 CBK24388.2 - 5.6e-11 42.7 0.1 2.3e-05 24.7 0.0 3.9 2 1 2 4 4 4 3 HEAT repeats Cnd1 PF12717.7 CBK24388.2 - 1.8e-07 31.3 2.7 0.0056 16.7 0.1 3.2 2 1 1 3 3 3 2 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 CBK24388.2 - 1.9e-07 31.5 1.2 0.0063 17.1 0.1 4.2 2 1 1 4 4 4 2 Vacuolar 14 Fab1-binding region Adaptin_N PF01602.20 CBK24388.2 - 5.5e-07 28.5 5.0 9.8e-06 24.4 0.8 2.1 1 1 0 2 2 2 2 Adaptin N terminal region HEAT_EZ PF13513.6 CBK24388.2 - 1.5e-06 28.6 0.2 0.0062 17.0 0.0 4.1 3 1 0 4 4 4 1 HEAT-like repeat CLASP_N PF12348.8 CBK24388.2 - 6.4e-05 22.6 0.1 0.037 13.6 0.1 2.7 3 0 0 3 3 3 2 CLASP N terminal Arm PF00514.23 CBK24388.2 - 0.00073 19.5 0.1 0.16 12.1 0.0 3.2 3 0 0 3 3 3 1 Armadillo/beta-catenin-like repeat DUF3730 PF12530.8 CBK24388.2 - 0.0011 18.6 0.3 1.2 8.7 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF3730) IFRD PF05004.13 CBK24388.2 - 0.0013 17.9 0.1 0.32 10.0 0.1 2.2 2 0 0 2 2 2 2 Interferon-related developmental regulator (IFRD) DNA_alkylation PF08713.11 CBK24388.2 - 0.002 17.9 0.1 0.33 10.6 0.0 3.0 2 2 1 3 3 3 1 DNA alkylation repair enzyme API5 PF05918.11 CBK24388.2 - 0.0028 16.5 4.3 4.5 6.0 0.2 3.2 2 1 0 3 3 3 3 Apoptosis inhibitory protein 5 (API5) TAF6_C PF07571.13 CBK24388.2 - 0.0086 16.4 0.1 3.8 7.9 0.0 3.2 2 1 0 2 2 2 1 TAF6 C-terminal HEAT repeat domain Pox_VLTF3 PF04947.14 CBK24388.2 - 0.05 13.3 0.6 9.2 6.0 0.0 2.7 2 1 0 2 2 2 0 Poxvirus Late Transcription Factor VLTF3 like DIM1 PF02966.16 CBK24389.2 - 1.6e-61 205.9 0.6 1.8e-61 205.8 0.6 1.0 1 0 0 1 1 1 1 Mitosis protein DIM1 Thioredoxin PF00085.20 CBK24389.2 - 0.0031 17.5 0.0 0.0039 17.1 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin RhaT PF06379.12 CBK24389.2 - 0.063 12.5 0.0 0.072 12.3 0.0 1.1 1 0 0 1 1 1 0 L-rhamnose-proton symport protein (RhaT) GidB PF02527.15 CBK24389.2 - 0.13 11.6 0.0 0.19 11.0 0.0 1.3 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G eIF2_C PF09173.11 CBK24390.2 - 5.5e-36 122.7 0.7 1.3e-35 121.5 0.7 1.7 1 0 0 1 1 1 1 Initiation factor eIF2 gamma, C terminal GTP_EFTU PF00009.27 CBK24390.2 - 4.9e-22 78.4 0.5 3.3e-21 75.7 0.5 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 CBK24390.2 - 6.5e-11 42.5 1.4 1.5e-10 41.3 1.4 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 CBK24390.2 - 0.0033 17.5 0.0 0.0071 16.4 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 CBK24390.2 - 0.0075 16.2 0.2 0.076 12.9 0.1 2.2 2 0 0 2 2 2 1 RsgA GTPase MMR_HSR1_Xtn PF16897.5 CBK24390.2 - 0.022 14.7 0.5 0.14 12.2 0.1 2.3 2 1 0 2 2 2 0 C-terminal region of MMR_HSR1 domain Protein_K PF12283.8 CBK24390.2 - 0.088 13.0 0.1 0.7 10.2 0.0 2.5 2 0 0 2 2 2 0 Bacteriophage protein K Dynamin_N PF00350.23 CBK24390.2 - 0.15 12.1 0.1 0.44 10.6 0.1 1.8 1 1 0 2 2 2 0 Dynamin family E3_binding PF02817.17 CBK24391.2 - 7.4e-08 32.6 0.0 1.8e-07 31.4 0.0 1.6 1 0 0 1 1 1 1 e3 binding domain 2-oxoacid_dh PF00198.23 CBK24391.2 - 5.5e-05 22.7 2.6 0.00022 20.7 2.6 2.1 1 1 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) DUF612 PF04747.12 CBK24391.2 - 0.0029 16.8 0.0 0.0029 16.8 0.0 1.4 2 0 0 2 2 2 1 Protein of unknown function, DUF612 Myco_19_kDa PF05481.12 CBK24391.2 - 0.032 14.5 0.3 0.07 13.4 0.3 1.6 1 0 0 1 1 1 0 Mycobacterium 19 kDa lipoprotein antigen SelK_SelG PF10961.8 CBK24393.2 - 4.8e-06 27.1 1.6 1.4e-05 25.6 1.6 1.8 1 0 0 1 1 1 1 Selenoprotein SelK_SelG Nucleotid_trans PF03407.16 CBK24393.2 - 0.03 14.3 0.0 0.047 13.6 0.0 1.2 1 0 0 1 1 1 0 Nucleotide-diphospho-sugar transferase HEAT_2 PF13646.6 CBK24394.2 - 0.0015 18.9 0.0 0.018 15.4 0.1 2.9 2 0 0 2 2 2 1 HEAT repeats HEAT PF02985.22 CBK24394.2 - 0.8 10.1 4.6 1.5 9.3 0.1 3.9 4 0 0 4 4 4 0 HEAT repeat GATase_5 PF13507.6 CBK24395.2 - 2.2e-97 325.2 0.0 3.3e-97 324.6 0.0 1.3 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain AIRS_C PF02769.22 CBK24395.2 - 6.7e-23 81.5 0.4 1.6e-12 47.8 0.0 2.5 2 0 0 2 2 2 2 AIR synthase related protein, C-terminal domain FGAR-AT_linker PF18072.1 CBK24395.2 - 2.2e-12 47.3 0.0 6e-12 45.9 0.0 1.8 1 0 0 1 1 1 1 Formylglycinamide ribonucleotide amidotransferase linker domain FGAR-AT_N PF18076.1 CBK24395.2 - 2.9e-12 46.6 0.0 5.8e-12 45.6 0.0 1.5 1 0 0 1 1 1 1 Formylglycinamide ribonucleotide amidotransferase N-terminal AIRS PF00586.24 CBK24395.2 - 0.0053 17.4 0.0 0.057 14.1 0.0 2.6 2 0 0 2 2 2 1 AIR synthase related protein, N-terminal domain HIT PF01230.23 CBK24396.2 - 2.5e-23 82.6 0.2 2.9e-23 82.4 0.2 1.1 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 CBK24396.2 - 2.7e-19 69.7 0.1 3.4e-19 69.4 0.1 1.0 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding TRAP_beta PF05753.14 CBK24397.2 - 1.2e-12 47.5 0.0 1.4e-12 47.3 0.0 1.0 1 0 0 1 1 1 1 Translocon-associated protein beta (TRAPB) SMC_N PF02463.19 CBK24398.2 - 5.9e-30 104.3 1.5 1.2e-29 103.4 1.5 1.6 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 CBK24398.2 - 4.8e-16 59.9 2.8 4.8e-16 59.9 2.8 6.0 3 2 2 5 5 2 1 AAA domain AAA_21 PF13304.6 CBK24398.2 - 0.00012 22.0 10.3 0.00077 19.4 0.1 3.1 2 1 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 CBK24398.2 - 0.0002 21.0 0.0 0.00041 20.0 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_15 PF13175.6 CBK24398.2 - 0.00099 18.9 23.3 0.00099 18.9 23.3 4.4 2 2 0 2 2 1 1 AAA ATPase domain AAA_22 PF13401.6 CBK24398.2 - 0.024 14.9 8.1 0.33 11.2 0.0 3.9 4 0 0 4 4 4 0 AAA domain SbcCD_C PF13558.6 CBK24398.2 - 0.057 13.7 0.0 0.2 11.9 0.0 1.9 1 0 0 1 1 1 0 Putative exonuclease SbcCD, C subunit DUF3235 PF11574.8 CBK24398.2 - 0.14 13.1 1.0 0.37 11.7 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3235) DUF3800 PF12686.7 CBK24398.2 - 0.22 12.2 10.9 2.2e+03 -0.8 10.5 4.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3800) ABC_tran PF00005.27 CBK24398.2 - 0.52 10.8 0.0 0.52 10.8 0.0 6.3 3 2 0 3 3 1 0 ABC transporter DUF1730 PF08331.10 CBK24398.2 - 0.71 9.8 2.5 1.5 8.8 0.0 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF1730) AAA_16 PF13191.6 CBK24398.2 - 2.3 8.5 0.0 2.3 8.5 0.0 4.1 3 2 1 4 4 4 0 AAA ATPase domain Matrilin_ccoil PF10393.9 CBK24398.2 - 6.3 6.8 11.1 40 4.2 1.2 5.0 4 0 0 4 4 4 0 Trimeric coiled-coil oligomerisation domain of matrilin NPV_P10 PF05531.12 CBK24398.2 - 7.3 7.1 33.3 0.13 12.7 0.8 7.5 6 2 1 7 7 7 0 Nucleopolyhedrovirus P10 protein Carboxyl_trans PF01039.22 CBK24399.2 - 8.3e-190 631.6 0.1 9.7e-190 631.4 0.1 1.0 1 0 0 1 1 1 1 Carboxyl transferase domain MdcE PF06833.11 CBK24399.2 - 0.0094 15.5 0.0 0.03 13.8 0.0 1.8 3 0 0 3 3 3 1 Malonate decarboxylase gamma subunit (MdcE) PPDK_N PF01326.19 CBK24400.2 - 1.6e-60 205.1 0.0 2.8e-60 204.3 0.0 1.4 1 0 0 1 1 1 1 Pyruvate phosphate dikinase, PEP/pyruvate binding domain PEP-utilizers PF00391.23 CBK24400.2 - 2.5e-19 68.8 0.3 6e-19 67.5 0.3 1.7 1 0 0 1 1 1 1 PEP-utilising enzyme, mobile domain He_PIG PF05345.12 CBK24401.2 - 0.0029 17.8 0.0 0.0095 16.1 0.0 1.8 1 0 0 1 1 1 1 Putative Ig domain DUF4834 PF16118.5 CBK24401.2 - 0.01 16.8 0.3 0.021 15.8 0.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) Sushi PF00084.20 CBK24401.2 - 0.11 13.1 3.9 0.13 12.8 0.6 2.5 2 0 0 2 2 2 0 Sushi repeat (SCR repeat) DUF4690 PF15756.5 CBK24401.2 - 0.17 12.5 0.7 0.43 11.2 0.7 1.7 1 0 0 1 1 1 0 Small Novel Rich in Cartilage FeoB_associated PF12669.7 CBK24401.2 - 1.6 9.2 7.7 4.3 7.8 7.7 1.7 1 0 0 1 1 1 0 FeoB-associated Cys-rich membrane protein Endomucin PF07010.12 CBK24401.2 - 2 8.3 13.6 5.6 6.9 13.6 1.7 1 1 0 1 1 1 0 Endomucin HSP90 PF00183.18 CBK24402.2 - 2.2e-198 660.4 53.9 2.2e-198 660.4 53.9 2.1 1 1 1 2 2 2 1 Hsp90 protein HATPase_c PF02518.26 CBK24402.2 - 5.7e-11 42.9 0.2 1.2e-10 41.8 0.2 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 CBK24402.2 - 4.6e-08 33.0 0.1 4.6e-08 33.0 0.1 2.8 3 0 0 3 3 3 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase BRO1 PF03097.18 CBK24403.2 - 1.1e-28 100.1 1.6 1.1e-28 100.1 1.6 1.8 2 0 0 2 2 2 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.6 CBK24403.2 - 3.1e-22 79.2 17.0 5.6e-22 78.4 14.5 2.5 2 1 0 2 2 2 1 ALIX V-shaped domain binding to HIV MscS_porin PF12795.7 CBK24403.2 - 0.0056 16.3 2.5 0.0056 16.3 2.5 3.0 2 1 0 2 2 2 1 Mechanosensitive ion channel porin domain TRPM_tetra PF16519.5 CBK24403.2 - 0.48 10.6 5.7 0.3 11.2 1.0 2.9 2 1 0 2 2 2 0 Tetramerisation domain of TRPM Snapin_Pallidin PF14712.6 CBK24403.2 - 0.63 10.5 13.2 1 9.9 0.2 4.5 4 1 0 4 4 4 0 Snapin/Pallidin HAUS6_N PF14661.6 CBK24403.2 - 1.5 8.4 9.6 4.4 6.8 5.2 3.2 1 1 2 3 3 3 0 HAUS augmin-like complex subunit 6 N-terminus PspA_IM30 PF04012.12 CBK24403.2 - 1.8 8.1 13.9 0.024 14.2 3.5 2.9 2 1 0 3 3 3 0 PspA/IM30 family APG6_N PF17675.1 CBK24403.2 - 2.2 8.8 16.0 5.8 7.4 0.6 3.4 2 1 1 3 3 3 0 Apg6 coiled-coil region DASH_Duo1 PF08651.10 CBK24403.2 - 6.4 6.6 9.5 0.68 9.8 0.0 3.8 5 0 0 5 5 5 0 DASH complex subunit Duo1 ACP_PD PF04336.12 CBK24403.2 - 7.1 7.1 8.0 28 5.2 0.9 3.8 3 1 0 3 3 3 0 Acyl carrier protein phosphodiesterase CLU_N PF15044.6 CBK24404.2 - 3.6e-16 59.3 0.1 1.1e-15 57.7 0.1 1.9 1 0 0 1 1 1 1 Mitochondrial function, CLU-N-term CLU PF13236.6 CBK24404.2 - 1e-15 58.2 0.0 2.9e-15 56.7 0.0 1.7 2 0 0 2 2 2 1 Clustered mitochondria DUF727 PF05303.12 CBK24404.2 - 1.7e-08 34.5 0.0 3.8e-08 33.3 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF727) Flagellin_IN PF07196.13 CBK24404.2 - 0.069 13.4 0.1 0.13 12.4 0.1 1.5 1 0 0 1 1 1 0 Flagellin hook IN motif 6PGD PF00393.19 CBK24405.2 - 8.6e-116 386.4 0.0 1.1e-115 386.0 0.0 1.1 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.15 CBK24405.2 - 1.2e-41 142.5 0.0 1.8e-41 141.9 0.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 3HCDH_N PF02737.18 CBK24405.2 - 0.14 12.0 0.0 0.25 11.2 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF1133 PF06576.11 CBK24405.2 - 0.14 11.5 0.0 0.26 10.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1133) NAD_binding_11 PF14833.6 CBK24405.2 - 0.15 12.3 0.0 0.49 10.7 0.0 1.9 2 0 0 2 2 2 0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase DUF563 PF04577.14 CBK24406.2 - 8.3e-16 58.8 0.7 1.1e-15 58.4 0.3 1.4 2 0 0 2 2 2 1 Protein of unknown function (DUF563) CofC PF01983.16 CBK24406.2 - 0.04 13.1 0.0 0.05 12.8 0.0 1.1 1 0 0 1 1 1 0 Guanylyl transferase CofC like Rod_cone_degen PF15201.6 CBK24406.2 - 0.069 13.3 0.1 0.17 12.0 0.1 1.6 1 0 0 1 1 1 0 Progressive rod-cone degeneration RAP1 PF07218.11 CBK24408.2 - 0.16 10.2 8.6 0.19 10.0 8.6 1.0 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) GREB1 PF15782.5 CBK24408.2 - 2.2 5.3 11.1 2.3 5.2 11.1 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Transformer PF06495.11 CBK24408.2 - 3.3 7.8 51.5 1.1 9.4 41.6 2.3 1 1 1 2 2 2 0 Fruit fly transformer protein DUF936 PF06075.12 CBK24408.2 - 3.8 6.3 19.4 4.5 6.1 19.4 1.1 1 0 0 1 1 1 0 Plant protein of unknown function (DUF936) SOBP PF15279.6 CBK24408.2 - 8.8 6.8 16.3 12 6.4 16.3 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein UPF0004 PF00919.20 CBK24410.2 - 4.6e-17 61.9 0.0 9.4e-17 60.9 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized protein family UPF0004 Radical_SAM PF04055.21 CBK24410.2 - 2.4e-14 54.0 0.0 3.9e-14 53.4 0.0 1.3 1 0 0 1 1 1 1 Radical SAM superfamily TRAM PF01938.20 CBK24410.2 - 0.0013 18.7 0.1 0.0039 17.2 0.0 1.9 2 0 0 2 2 2 1 TRAM domain Polysacc_deac_2 PF04748.13 CBK24410.2 - 0.028 13.6 0.0 0.058 12.6 0.0 1.5 1 0 0 1 1 1 0 Divergent polysaccharide deacetylase HEPN_RES_NTD1 PF18870.1 CBK24410.2 - 0.086 13.0 0.0 0.17 12.1 0.0 1.5 1 0 0 1 1 1 0 HEPN/RES N-terminal domain 1 AAA PF00004.29 CBK24412.2 - 8.1e-16 58.7 0.0 7.8e-12 45.8 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 CBK24412.2 - 3.5e-06 27.4 0.0 0.00061 20.1 0.0 2.8 1 1 1 2 2 2 1 RNA helicase UFD1 PF03152.14 CBK24412.2 - 8.5e-05 22.1 0.0 0.00021 20.8 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 T2SSE PF00437.20 CBK24412.2 - 0.0002 20.5 0.0 0.00046 19.3 0.0 1.6 1 0 0 1 1 1 1 Type II/IV secretion system protein NACHT PF05729.12 CBK24412.2 - 0.0019 18.1 0.0 0.045 13.7 0.0 2.4 2 0 0 2 2 2 1 NACHT domain AAA_19 PF13245.6 CBK24412.2 - 0.0035 17.7 0.0 0.0083 16.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain FtsK_SpoIIIE PF01580.18 CBK24412.2 - 0.0071 15.7 0.1 0.014 14.8 0.1 1.4 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_33 PF13671.6 CBK24412.2 - 0.01 16.0 0.0 0.022 14.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.9 CBK24412.2 - 0.012 14.9 0.0 0.017 14.4 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_22 PF13401.6 CBK24412.2 - 0.015 15.6 0.0 0.047 14.0 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 CBK24412.2 - 0.015 14.8 0.1 0.051 13.1 0.1 1.9 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_18 PF13238.6 CBK24412.2 - 0.017 15.6 0.0 0.038 14.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_lid_3 PF17862.1 CBK24412.2 - 0.028 14.2 0.0 0.062 13.1 0.0 1.5 1 0 0 1 1 1 0 AAA+ lid domain AAA_29 PF13555.6 CBK24412.2 - 0.035 13.8 0.3 0.55 10.0 0.3 2.3 2 0 0 2 2 2 0 P-loop containing region of AAA domain Zeta_toxin PF06414.12 CBK24412.2 - 0.036 13.3 0.0 0.07 12.4 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_14 PF13173.6 CBK24412.2 - 0.039 14.0 0.0 0.12 12.4 0.0 1.9 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 CBK24412.2 - 0.043 13.7 0.1 0.1 12.5 0.1 1.6 1 0 0 1 1 1 0 NTPase TrwB_AAD_bind PF10412.9 CBK24412.2 - 0.067 12.1 0.1 0.15 11.0 0.1 1.5 1 1 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain ABC_tran PF00005.27 CBK24412.2 - 0.078 13.5 0.0 0.19 12.3 0.0 1.7 1 0 0 1 1 1 0 ABC transporter AAA_16 PF13191.6 CBK24412.2 - 0.091 13.1 0.3 1.4 9.2 0.4 2.9 2 1 0 2 2 2 0 AAA ATPase domain cobW PF02492.19 CBK24412.2 - 0.11 12.1 0.0 0.3 10.7 0.0 1.7 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.6 CBK24412.2 - 0.11 12.2 0.0 1.2 8.8 0.0 2.4 3 0 0 3 3 3 0 AAA domain Antibiotic_NAT PF02522.14 CBK24412.2 - 0.2 11.5 0.0 0.3 10.9 0.0 1.3 1 0 0 1 1 1 0 Aminoglycoside 3-N-acetyltransferase AAA_23 PF13476.6 CBK24412.2 - 1.1 9.7 4.0 1.5 9.3 2.7 1.8 1 1 0 1 1 1 0 AAA domain Glyco_transf_49 PF13896.6 CBK24414.2 - 1.5e-09 37.7 3.4 3.4e-09 36.5 0.5 2.4 2 1 0 2 2 2 1 Glycosyl-transferase for dystroglycan FBA_1 PF07734.13 CBK24414.2 - 0.0011 18.9 0.8 0.0035 17.3 0.6 2.0 1 1 1 2 2 2 2 F-box associated RNase_P_pop3 PF08228.11 CBK24415.2 - 0.089 12.8 0.0 0.17 11.9 0.0 1.4 1 0 0 1 1 1 0 RNase P subunit Pop3 Ribosomal_L7Ae PF01248.26 CBK24417.2 - 1.3e-21 76.1 0.6 2.1e-21 75.4 0.6 1.4 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.11 CBK24417.2 - 0.051 13.6 0.0 0.06 13.4 0.0 1.2 1 0 0 1 1 1 0 RNase P subunit Pop3 Glyco_transf_49 PF13896.6 CBK24419.2 - 3.2e-21 76.1 7.8 7.1e-17 61.8 4.3 2.3 1 1 1 2 2 2 2 Glycosyl-transferase for dystroglycan PyrI_C PF02748.15 CBK24419.2 - 0.077 12.9 4.0 0.21 11.5 1.1 2.4 2 0 0 2 2 2 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain PHD PF00628.29 CBK24421.2 - 4.6e-06 26.4 12.5 8e-06 25.7 12.5 1.4 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 CBK24421.2 - 0.12 11.9 9.0 0.26 10.9 9.0 1.6 1 0 0 1 1 1 0 PHD-finger Collagen PF01391.18 CBK24421.2 - 0.24 11.2 7.6 0.48 10.2 7.6 1.5 1 0 0 1 1 1 0 Collagen triple helix repeat (20 copies) PHD PF00628.29 CBK24422.2 - 7e-08 32.2 11.9 9.7e-08 31.8 11.9 1.2 1 0 0 1 1 1 1 PHD-finger PHF5 PF03660.14 CBK24422.2 - 0.0082 16.3 4.7 0.0087 16.3 4.7 1.1 1 0 0 1 1 1 1 PHF5-like protein PHD_2 PF13831.6 CBK24422.2 - 0.0099 15.4 7.7 0.0099 15.4 7.7 2.1 1 1 1 2 2 2 1 PHD-finger Prok-RING_1 PF14446.6 CBK24422.2 - 0.027 14.4 6.2 0.027 14.4 6.2 2.0 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 DZR PF12773.7 CBK24422.2 - 0.056 13.5 10.6 0.29 11.2 5.7 2.1 1 1 1 2 2 2 0 Double zinc ribbon zf-C2H2_3 PF13878.6 CBK24422.2 - 0.34 10.8 0.2 0.34 10.8 0.2 2.4 2 1 1 3 3 3 0 zinc-finger of acetyl-transferase ESCO Glyco_hydro_47 PF01532.20 CBK24423.2 - 1.2e-98 331.0 0.0 1.3e-98 330.9 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Rep_fac_C PF08542.11 CBK24424.2 - 3.1e-20 72.4 0.0 9.3e-20 70.8 0.0 1.8 2 0 0 2 2 1 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.6 CBK24424.2 - 7e-14 51.9 0.1 1.1e-09 38.3 0.2 2.2 1 1 1 2 2 2 2 DNA polymerase III, delta subunit AAA PF00004.29 CBK24424.2 - 1.4e-12 48.2 0.0 2.2e-12 47.6 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 CBK24424.2 - 7.9e-07 28.9 0.0 1.6e-06 27.9 0.0 1.7 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain Rad17 PF03215.15 CBK24424.2 - 8.1e-07 29.1 0.0 4.5e-06 26.7 0.0 1.9 1 1 0 2 2 2 1 Rad17 P-loop domain AAA_22 PF13401.6 CBK24424.2 - 9e-06 26.0 0.1 0.0055 17.0 0.1 2.3 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 CBK24424.2 - 1.2e-05 25.8 0.1 0.0013 19.2 0.0 2.2 1 1 1 2 2 2 1 AAA ATPase domain AAA_14 PF13173.6 CBK24424.2 - 2.9e-05 24.1 0.0 4.8e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 CBK24424.2 - 6e-05 22.5 0.3 0.0005 19.5 0.1 2.1 1 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 CBK24424.2 - 0.0001 22.1 0.0 0.00026 20.9 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 CBK24424.2 - 0.00013 22.0 0.1 0.00089 19.3 0.1 2.3 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_11 PF13086.6 CBK24424.2 - 0.00035 20.4 0.0 0.00046 20.1 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 CBK24424.2 - 0.00062 19.5 0.0 0.0011 18.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.6 CBK24424.2 - 0.00075 19.1 0.2 0.0014 18.3 0.2 1.4 1 1 0 1 1 1 1 AAA domain AAA_24 PF13479.6 CBK24424.2 - 0.0019 18.0 0.0 0.003 17.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 CBK24424.2 - 0.002 18.5 0.2 0.0082 16.5 0.2 1.8 1 1 0 1 1 1 1 AAA domain AAA_7 PF12775.7 CBK24424.2 - 0.004 16.7 0.0 0.0058 16.2 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_assoc_2 PF16193.5 CBK24424.2 - 0.0043 17.4 0.0 0.013 15.9 0.0 1.8 1 0 0 1 1 1 1 AAA C-terminal domain Viral_helicase1 PF01443.18 CBK24424.2 - 0.017 14.9 0.0 0.026 14.3 0.0 1.2 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase SRP54 PF00448.22 CBK24424.2 - 0.018 14.7 0.0 0.04 13.5 0.0 1.5 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain DUF4470 PF14737.6 CBK24424.2 - 0.023 14.9 0.0 0.078 13.2 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4470) MeaB PF03308.16 CBK24424.2 - 0.027 13.5 0.1 0.064 12.2 0.0 1.6 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB IstB_IS21 PF01695.17 CBK24424.2 - 0.028 14.1 0.4 0.11 12.2 0.4 1.9 1 1 0 1 1 1 0 IstB-like ATP binding protein AAA_18 PF13238.6 CBK24424.2 - 0.032 14.8 0.1 0.051 14.1 0.1 1.5 1 1 0 1 1 1 0 AAA domain MCM PF00493.23 CBK24424.2 - 0.038 13.1 0.0 0.091 11.8 0.0 1.7 1 1 0 1 1 1 0 MCM P-loop domain RNA_helicase PF00910.22 CBK24424.2 - 0.056 13.8 0.0 0.22 11.9 0.0 2.1 1 1 0 1 1 1 0 RNA helicase MipZ PF09140.11 CBK24424.2 - 0.067 12.5 0.0 0.098 11.9 0.0 1.2 1 0 0 1 1 1 0 ATPase MipZ AAA_28 PF13521.6 CBK24424.2 - 0.09 13.0 0.0 0.24 11.6 0.0 1.6 1 1 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.18 CBK24424.2 - 0.11 11.9 0.0 0.19 11.0 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family NTPase_1 PF03266.15 CBK24424.2 - 0.14 12.1 0.1 0.83 9.5 0.1 2.1 1 1 1 2 2 2 0 NTPase BPL_N PF09825.9 CBK24425.2 - 7.3e-42 143.8 0.0 8.9e-42 143.5 0.0 1.1 1 0 0 1 1 1 1 Biotin-protein ligase, N terminal GATase_3 PF07685.14 CBK24425.2 - 0.0007 19.2 0.0 0.00099 18.8 0.0 1.2 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain GATase PF00117.28 CBK24425.2 - 0.0015 18.3 0.0 0.0018 18.1 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I LBP_M PF17385.2 CBK24425.2 - 0.14 11.6 0.0 0.18 11.3 0.0 1.2 1 0 0 1 1 1 0 Lacto-N-biose phosphorylase central domain IKI3 PF04762.12 CBK24426.2 - 4.3e-28 97.9 0.1 6.3e-28 97.3 0.1 1.2 1 0 0 1 1 1 1 IKI3 family TPR_2 PF07719.17 CBK24426.2 - 0.079 13.1 1.3 0.37 11.0 0.5 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat HSP70 PF00012.20 CBK24427.2 - 2.1e-29 102.2 0.1 2.6e-29 101.9 0.1 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 CBK24427.2 - 1.7e-09 37.0 0.1 2.2e-08 33.3 0.0 2.1 2 0 0 2 2 2 1 MreB/Mbl protein StbA PF06406.11 CBK24427.2 - 0.026 13.8 0.0 0.046 13.0 0.0 1.4 1 0 0 1 1 1 0 StbA protein Hexokinase_1 PF00349.21 CBK24427.2 - 0.068 13.1 0.0 1.1 9.1 0.0 2.6 2 2 0 2 2 2 0 Hexokinase Methyltransf_8 PF05148.15 CBK24427.2 - 0.13 12.1 0.0 14 5.5 0.0 2.4 2 1 0 2 2 2 0 Hypothetical methyltransferase DUF4379 PF14311.6 CBK24428.2 - 1.1e-37 128.1 18.5 2.1e-18 66.4 2.7 3.2 3 0 0 3 3 3 3 Probable Zinc-ribbon domain PhageMin_Tail PF10145.9 CBK24429.2 - 0.013 15.4 13.5 0.022 14.6 13.5 1.2 1 0 0 1 1 1 0 Phage-related minor tail protein DUF4684 PF15736.5 CBK24429.2 - 2.1 6.9 3.7 4.2 5.9 3.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4684) Methyltransf_11 PF08241.12 CBK24430.2 - 1.3e-15 57.8 0.0 1.8e-15 57.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CBK24430.2 - 1.5e-13 50.8 0.1 1.7e-13 50.7 0.1 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CBK24430.2 - 4.1e-12 46.7 0.0 7.5e-12 45.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CBK24430.2 - 2.6e-08 34.5 0.0 3.4e-08 34.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 CBK24430.2 - 0.0026 17.6 0.0 0.0036 17.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 CBK24430.2 - 0.0065 15.8 0.1 0.0082 15.5 0.1 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MetW PF07021.12 CBK24430.2 - 0.016 14.8 0.0 0.021 14.4 0.0 1.2 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Methyltransf_29 PF03141.16 CBK24430.2 - 0.022 13.3 0.0 0.026 13.1 0.0 1.1 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase NodS PF05401.11 CBK24430.2 - 0.04 13.5 0.0 0.048 13.3 0.0 1.1 1 0 0 1 1 1 0 Nodulation protein S (NodS) Methyltransf_8 PF05148.15 CBK24430.2 - 0.049 13.5 0.3 0.14 12.0 0.3 1.8 1 1 0 1 1 1 0 Hypothetical methyltransferase E1-E2_ATPase PF00122.20 CBK24431.2 - 2e-09 37.2 1.2 4.8e-09 36.0 1.2 1.6 1 1 0 1 1 1 1 E1-E2 ATPase V-ATPase_G PF03179.15 CBK24432.2 - 2.9e-24 85.6 14.3 3.5e-24 85.4 14.3 1.1 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit vATP-synt_E PF01991.18 CBK24432.2 - 0.00053 19.5 10.4 0.00067 19.1 10.4 1.1 1 0 0 1 1 1 1 ATP synthase (E/31 kDa) subunit DUF3552 PF12072.8 CBK24432.2 - 0.0023 17.4 14.5 0.0023 17.4 14.5 1.8 1 1 1 2 2 2 1 Domain of unknown function (DUF3552) DDRGK PF09756.9 CBK24432.2 - 0.12 11.9 13.6 0.17 11.5 13.6 1.1 1 0 0 1 1 1 0 DDRGK domain Tho2 PF11262.8 CBK24432.2 - 0.22 10.7 4.9 0.27 10.4 4.9 1.2 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 RRF PF01765.19 CBK24432.2 - 0.29 11.1 9.6 0.36 10.8 9.2 1.4 1 1 0 1 1 1 0 Ribosome recycling factor TetR_C_24 PF17932.1 CBK24432.2 - 0.33 11.2 3.6 0.43 10.9 0.1 2.1 1 1 1 2 2 2 0 Tetracyclin repressor-like, C-terminal domain V-ATPase_G_2 PF16999.5 CBK24432.2 - 0.5 10.8 19.6 1.4 9.4 14.5 2.1 1 1 1 2 2 2 0 Vacuolar (H+)-ATPase G subunit DUF4407 PF14362.6 CBK24432.2 - 0.98 8.7 6.9 1.3 8.3 6.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) ATP-synt_B PF00430.18 CBK24432.2 - 1 9.5 20.4 0.25 11.4 14.8 2.0 1 1 1 2 2 2 0 ATP synthase B/B' CF(0) Sec62 PF03839.16 CBK24432.2 - 1.9 7.9 6.6 2.5 7.6 6.6 1.2 1 0 0 1 1 1 0 Translocation protein Sec62 NAP PF00956.18 CBK24432.2 - 2.2 7.4 13.8 0.5 9.5 0.6 2.0 1 1 1 2 2 2 0 Nucleosome assembly protein (NAP) DivIVA PF05103.13 CBK24432.2 - 4.7 7.3 17.7 2.5 8.2 10.4 2.1 1 1 0 2 2 2 0 DivIVA protein DUF883 PF05957.13 CBK24432.2 - 5.6 7.6 9.6 5.2 7.7 8.0 1.7 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) Presenilin PF01080.17 CBK24432.2 - 6 5.5 6.1 6.4 5.4 6.1 1.1 1 0 0 1 1 1 0 Presenilin OmpH PF03938.14 CBK24432.2 - 6.6 7.1 19.7 8.8 6.7 18.9 1.6 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) LAP1C PF05609.12 CBK24433.2 - 0.089 11.9 12.4 0.1 11.6 12.4 1.0 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) PRP38_assoc PF12871.7 CBK24433.2 - 2 9.0 76.4 8.3 7.1 73.2 2.3 1 1 1 2 2 2 0 Pre-mRNA-splicing factor 38-associated hydrophilic C-term SRP-alpha_N PF04086.13 CBK24433.2 - 2.1 8.2 23.0 2.6 7.9 23.0 1.0 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal ALMT PF11744.8 CBK24433.2 - 2.8 6.7 8.5 3.7 6.3 8.5 1.4 1 0 0 1 1 1 0 Aluminium activated malate transporter Ndc1_Nup PF09531.10 CBK24433.2 - 3.1 6.4 13.3 3.4 6.2 13.3 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Nucleo_P87 PF07267.11 CBK24433.2 - 3.1 6.5 22.1 3.9 6.2 22.1 1.0 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 SPX PF03105.19 CBK24433.2 - 3.3 7.6 26.0 4.1 7.2 26.0 1.1 1 0 0 1 1 1 0 SPX domain VIR_N PF15912.5 CBK24433.2 - 7.7 6.0 14.6 9.6 5.7 14.6 1.1 1 0 0 1 1 1 0 Virilizer, N-terminal WDCP PF15390.6 CBK24433.2 - 8.3 4.6 10.9 9.2 4.5 10.9 1.1 1 0 0 1 1 1 0 WD repeat and coiled-coil-containing protein family SH3_1 PF00018.28 CBK24434.2 - 3.6e-16 58.5 0.1 4.1e-16 58.3 0.1 1.1 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 CBK24434.2 - 5.9e-12 45.3 0.0 6.8e-12 45.1 0.0 1.1 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 CBK24434.2 - 1e-08 34.7 0.1 1.4e-08 34.3 0.1 1.1 1 0 0 1 1 1 1 Variant SH3 domain FtsJ PF01728.19 CBK24435.2 - 5.2e-70 235.1 0.3 6.4e-70 234.8 0.3 1.1 1 0 0 1 1 1 1 FtsJ-like methyltransferase SDA1 PF05285.12 CBK24436.2 - 0.049 13.1 27.3 0.057 12.8 27.3 1.1 1 0 0 1 1 1 0 SDA1 BUD22 PF09073.10 CBK24436.2 - 2.2 7.6 30.2 2.6 7.3 30.2 1.2 1 0 0 1 1 1 0 BUD22 DNA_pol_phi PF04931.13 CBK24436.2 - 3.9 5.4 31.8 5.1 5.1 31.8 1.1 1 0 0 1 1 1 0 DNA polymerase phi ALMT PF11744.8 CBK24436.2 - 4.3 6.0 5.6 5 5.9 5.6 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter CDC27 PF09507.10 CBK24436.2 - 4.9 6.4 32.7 5.8 6.2 32.7 1.0 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Sin3_corepress PF08295.12 CBK24437.2 - 9.3e-27 93.0 0.1 2.1e-26 91.8 0.1 1.6 1 0 0 1 1 1 1 Sin3 family co-repressor HSP70 PF00012.20 CBK24438.2 - 3.3e-249 828.1 8.6 1e-248 826.5 8.6 1.6 1 1 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 CBK24438.2 - 5.6e-15 55.0 0.2 1e-13 50.8 0.0 2.1 2 0 0 2 2 2 1 MreB/Mbl protein DDR PF08841.10 CBK24438.2 - 0.032 13.2 0.1 0.06 12.3 0.1 1.5 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain Hydantoinase_A PF01968.18 CBK24438.2 - 0.033 13.4 0.1 0.065 12.5 0.1 1.5 1 0 0 1 1 1 0 Hydantoinase/oxoprolinase FKS1_dom1 PF14288.6 CBK24438.2 - 0.11 12.9 0.2 9.3 6.6 0.0 2.4 2 0 0 2 2 2 0 1,3-beta-glucan synthase subunit FKS1, domain-1 PBP_sp32 PF07222.12 CBK24438.2 - 6.7 6.1 6.7 15 4.9 6.3 1.7 1 1 0 1 1 1 0 Proacrosin binding protein sp32 WD40 PF00400.32 CBK24439.2 - 1.7e-27 95.1 24.1 1.8e-06 28.6 0.2 8.9 10 0 0 10 10 10 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBK24439.2 - 8e-15 54.9 0.0 2.5e-05 24.5 0.0 5.3 3 2 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Bromodomain PF00439.25 CBK24440.2 - 1.2e-30 105.4 19.5 2.2e-17 62.9 0.7 6.4 5 1 0 5 5 5 5 Bromodomain LuxT_C PF18285.1 CBK24440.2 - 0.14 12.7 0.0 40 4.8 0.0 3.1 2 0 0 2 2 2 0 Tetracycline repressor LuxT C-terminal domain Peptidase_M20 PF01546.28 CBK24441.2 - 3e-17 63.0 0.0 1.1e-16 61.2 0.0 1.9 2 1 0 2 2 2 1 Peptidase family M20/M25/M40 Peptidase_M42 PF05343.14 CBK24441.2 - 0.014 14.5 0.0 0.086 11.9 0.0 2.0 2 0 0 2 2 2 0 M42 glutamyl aminopeptidase M20_dimer PF07687.14 CBK24441.2 - 0.032 14.1 0.0 0.072 13.0 0.0 1.6 1 0 0 1 1 1 0 Peptidase dimerisation domain HOOK PF05622.12 CBK24442.2 - 2.6e-11 42.4 70.6 4.4e-09 35.1 0.4 4.6 3 1 1 4 4 4 3 HOOK protein TACC_C PF05010.14 CBK24442.2 - 0.0054 16.5 8.1 0.0054 16.5 8.1 4.7 2 2 1 4 4 4 1 Transforming acidic coiled-coil-containing protein (TACC), C-terminal YscO PF07321.12 CBK24442.2 - 0.012 15.6 15.0 0.012 15.6 15.0 5.8 3 2 1 5 5 3 0 Type III secretion protein YscO TMF_DNA_bd PF12329.8 CBK24442.2 - 0.014 15.4 11.0 0.014 15.4 11.0 7.5 4 1 3 8 8 8 0 TATA element modulatory factor 1 DNA binding CH PF00307.31 CBK24442.2 - 0.02 15.1 0.0 0.098 12.8 0.0 2.2 2 0 0 2 2 2 0 Calponin homology (CH) domain ACT_6 PF13740.6 CBK24442.2 - 0.19 11.7 0.9 2.3 8.3 0.0 3.1 3 0 0 3 3 3 0 ACT domain APG6_N PF17675.1 CBK24442.2 - 0.35 11.4 90.8 0.19 12.3 24.8 5.3 3 2 2 5 5 5 0 Apg6 coiled-coil region DUF4407 PF14362.6 CBK24442.2 - 0.57 9.5 44.2 0.04 13.3 6.4 3.8 2 1 1 3 3 3 0 Domain of unknown function (DUF4407) Spc7 PF08317.11 CBK24442.2 - 2.1 7.2 70.4 1.2 8.0 18.1 4.4 3 1 1 4 4 4 0 Spc7 kinetochore protein ATG16 PF08614.11 CBK24442.2 - 2.2 8.4 71.9 2.4 8.4 16.7 4.4 2 2 1 3 3 3 0 Autophagy protein 16 (ATG16) DUF724 PF05266.14 CBK24442.2 - 3.3 7.5 52.7 0.64 9.8 7.7 4.8 2 2 2 4 4 4 0 Protein of unknown function (DUF724) ADIP PF11559.8 CBK24442.2 - 3.8 7.6 72.7 0.37 10.9 9.5 5.9 3 1 2 5 5 5 0 Afadin- and alpha -actinin-Binding Arg_decarbox_C PF17944.1 CBK24442.2 - 7.7 7.2 10.1 3.7 8.2 0.6 4.6 4 0 0 4 4 4 0 Arginine decarboxylase C-terminal helical extension ATG27 PF09451.10 CBK24443.2 - 2.4e-09 37.5 0.1 5.4e-09 36.3 0.1 1.6 1 1 0 1 1 1 1 Autophagy-related protein 27 CIMR PF00878.18 CBK24443.2 - 0.065 13.3 4.3 0.36 10.9 0.2 2.4 2 0 0 2 2 2 0 Cation-independent mannose-6-phosphate receptor repeat WAK_assoc PF14380.6 CBK24443.2 - 0.17 12.6 6.5 0.67 10.7 3.7 2.6 3 0 0 3 3 3 0 Wall-associated receptor kinase C-terminal Sdh_cyt PF01127.22 CBK24443.2 - 0.24 11.4 0.4 0.48 10.5 0.1 1.7 2 0 0 2 2 2 0 Succinate dehydrogenase/Fumarate reductase transmembrane subunit Pkinase PF00069.25 CBK24444.2 - 5.5e-63 212.8 0.0 7.2e-63 212.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBK24444.2 - 5.2e-42 143.9 0.0 9.6e-42 143.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.28 CBK24444.2 - 2e-07 31.2 0.0 7e-07 29.5 0.0 1.9 2 0 0 2 2 2 1 P21-Rho-binding domain Kinase-like PF14531.6 CBK24444.2 - 1.1e-05 25.0 0.0 0.0007 19.0 0.0 2.2 1 1 1 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 CBK24444.2 - 1.8e-05 23.7 0.0 2.5e-05 23.2 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase NdhS PF11623.8 CBK24444.2 - 0.036 13.7 0.0 0.072 12.8 0.0 1.4 1 0 0 1 1 1 0 NAD(P)H dehydrogenase subunit S DUF3867 PF12983.7 CBK24444.2 - 0.052 13.6 0.0 0.25 11.4 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3867) Haspin_kinase PF12330.8 CBK24444.2 - 0.077 11.9 0.2 0.14 11.1 0.2 1.3 1 1 0 1 1 1 0 Haspin like kinase domain PWI PF01480.17 CBK24445.2 - 0.0031 17.8 0.2 0.0087 16.4 0.1 1.9 1 1 0 1 1 1 1 PWI domain PRKCSH_1 PF13015.6 CBK24445.2 - 0.3 10.8 3.1 11 5.7 0.1 2.3 2 0 0 2 2 2 0 Glucosidase II beta subunit-like protein Swi6_N PF18530.1 CBK24445.2 - 0.34 11.1 6.0 0.036 14.2 1.3 2.0 2 1 0 2 2 2 0 Swi6 N-terminal domain Asp-B-Hydro_N PF05279.11 CBK24445.2 - 4.1 7.4 18.4 6.4 6.8 18.4 1.3 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region ENTH PF01417.20 CBK24446.2 - 8.9e-24 83.9 0.1 1.6e-23 83.1 0.1 1.5 1 0 0 1 1 1 1 ENTH domain AAT PF03417.16 CBK24446.2 - 1.3e-19 70.8 0.0 1.3e-19 70.8 0.0 2.2 2 0 0 2 2 2 1 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase eIF-3_zeta PF05091.12 CBK24446.2 - 7.3 5.4 17.7 13 4.7 17.7 1.3 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Symplekin_C PF12295.8 CBK24447.2 - 0.24 11.5 3.6 0.53 10.3 0.2 2.6 1 1 1 2 2 2 0 Symplekin tight junction protein C terminal Proteasome PF00227.26 CBK24448.2 - 5.9e-43 146.6 0.0 7.5e-43 146.2 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Pkinase PF00069.25 CBK24449.2 - 1.4e-25 90.1 0.0 5.2e-24 85.0 0.0 2.1 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBK24449.2 - 1.3e-19 70.5 0.0 3e-19 69.3 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.23 CBK24449.2 - 0.00056 19.9 0.0 0.00085 19.3 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family FTA2 PF13095.6 CBK24449.2 - 0.042 13.5 0.0 0.061 12.9 0.0 1.2 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Pkinase_fungal PF17667.1 CBK24449.2 - 0.076 11.8 3.8 0.12 11.1 0.0 2.1 2 0 0 2 2 2 0 Fungal protein kinase Kdo PF06293.14 CBK24449.2 - 0.16 11.3 0.0 0.23 10.8 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Syntaxin PF00804.25 CBK24450.2 - 0.004 16.9 2.8 0.0046 16.7 2.8 1.3 1 1 0 1 1 1 1 Syntaxin Pkinase PF00069.25 CBK24450.2 - 0.0094 15.3 0.5 0.012 14.9 0.0 1.4 2 0 0 2 2 2 1 Protein kinase domain PL48 PF15903.5 CBK24450.2 - 0.031 13.2 1.0 0.03 13.3 1.0 1.1 1 0 0 1 1 1 0 Filopodia upregulated, FAM65 Ribosomal_S8e PF01201.22 CBK24451.2 - 3.3e-38 130.9 0.0 4.2e-38 130.6 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S8e DUF2771 PF10969.8 CBK24452.2 - 0.0028 17.7 1.3 0.0059 16.7 1.3 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2771) CcmD PF04995.14 CBK24452.2 - 0.0087 16.1 1.9 0.019 15.0 1.9 1.6 1 0 0 1 1 1 1 Heme exporter protein D (CcmD) EphA2_TM PF14575.6 CBK24452.2 - 0.009 16.9 0.2 0.022 15.6 0.2 1.6 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain RIFIN PF02009.16 CBK24452.2 - 0.017 15.1 0.0 0.024 14.5 0.0 1.2 1 0 0 1 1 1 0 Rifin DUF5385 PF17359.2 CBK24452.2 - 0.059 12.9 0.1 0.1 12.2 0.1 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5385) SP_C-Propep PF08999.10 CBK24452.2 - 0.062 13.1 2.3 0.13 12.0 2.3 1.5 1 0 0 1 1 1 0 Surfactant protein C, N terminal propeptide TMEM154 PF15102.6 CBK24452.2 - 0.063 13.2 0.2 0.11 12.4 0.2 1.4 1 0 0 1 1 1 0 TMEM154 protein family DUF898 PF05987.13 CBK24452.2 - 0.12 11.4 0.0 0.19 10.8 0.0 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF898) Orf78 PF06024.12 CBK24452.2 - 0.12 12.7 0.1 0.22 11.9 0.1 1.4 1 0 0 1 1 1 0 Orf78 (ac78) DUF3302 PF11742.8 CBK24452.2 - 0.17 12.0 4.5 0.32 11.2 4.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3302) Syndecan PF01034.20 CBK24452.2 - 0.17 11.8 1.3 0.34 10.8 1.3 1.4 1 0 0 1 1 1 0 Syndecan domain DUF4083 PF13314.6 CBK24452.2 - 0.2 11.6 0.8 0.44 10.5 0.8 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4083) TRAP_alpha PF03896.16 CBK24452.2 - 0.22 10.7 0.9 0.64 9.2 0.1 1.9 2 0 0 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit Cadherin_C_2 PF16492.5 CBK24452.2 - 1.6 9.5 4.2 0.93 10.3 0.3 2.6 3 0 0 3 3 2 0 Cadherin cytoplasmic C-terminal Ribosomal_S13_N PF08069.12 CBK24453.2 - 2.7e-29 101.0 0.3 6.9e-29 99.7 0.1 1.8 2 0 0 2 2 2 1 Ribosomal S13/S15 N-terminal domain Ribosomal_S15 PF00312.22 CBK24453.2 - 7.1e-16 58.2 0.8 9.1e-16 57.8 0.8 1.2 1 0 0 1 1 1 1 Ribosomal protein S15 Pkinase PF00069.25 CBK24454.2 - 3.2e-69 233.2 0.0 3.7e-69 233.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBK24454.2 - 1.7e-37 129.1 0.0 2e-37 128.9 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase FTA2 PF13095.6 CBK24454.2 - 4.3e-06 26.5 0.0 0.011 15.4 0.0 2.1 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Kinase-like PF14531.6 CBK24454.2 - 3.4e-05 23.3 0.0 6e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 CBK24454.2 - 0.034 13.5 0.0 0.2 11.0 0.0 1.9 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CBK24454.2 - 0.038 13.9 0.0 0.055 13.4 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 CBK24454.2 - 0.089 11.8 0.1 1.4 7.9 0.0 2.1 2 0 0 2 2 2 0 Seadornavirus VP7 AAA_2 PF07724.14 CBK24456.2 - 3.2e-54 183.6 0.0 2.7e-52 177.3 0.0 3.0 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_lid_9 PF17871.1 CBK24456.2 - 1.3e-36 124.6 2.7 1.3e-36 124.6 2.7 3.2 3 0 0 3 3 2 1 AAA lid domain AAA PF00004.29 CBK24456.2 - 4.5e-26 91.8 0.8 2.5e-15 57.0 0.0 3.3 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.9 CBK24456.2 - 3.7e-22 78.2 1.5 2.3e-21 75.6 0.1 3.1 2 0 0 2 2 2 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.14 CBK24456.2 - 4.7e-16 59.0 1.8 9.9e-11 41.8 0.0 3.5 3 1 0 3 3 2 2 AAA domain (dynein-related subfamily) Clp_N PF02861.20 CBK24456.2 - 5.9e-15 55.1 2.0 3.4e-07 30.3 0.0 4.1 4 0 0 4 4 4 2 Clp amino terminal domain, pathogenicity island component AAA_16 PF13191.6 CBK24456.2 - 1.8e-12 48.0 7.3 5.2e-06 26.9 0.0 5.0 3 2 1 5 5 4 2 AAA ATPase domain AAA_22 PF13401.6 CBK24456.2 - 1.3e-11 44.9 2.1 0.00076 19.8 0.0 4.9 3 2 0 3 3 3 2 AAA domain AAA_14 PF13173.6 CBK24456.2 - 5.4e-08 33.0 0.4 0.013 15.5 0.0 3.5 3 0 0 3 3 2 2 AAA domain IstB_IS21 PF01695.17 CBK24456.2 - 1.2e-07 31.7 0.0 0.018 14.8 0.0 2.7 2 0 0 2 2 2 2 IstB-like ATP binding protein Sigma54_activat PF00158.26 CBK24456.2 - 5.5e-07 29.4 0.0 0.00017 21.4 0.0 3.0 3 0 0 3 3 2 1 Sigma-54 interaction domain AAA_7 PF12775.7 CBK24456.2 - 8.6e-07 28.6 0.0 0.0079 15.7 0.0 2.8 2 1 0 2 2 2 2 P-loop containing dynein motor region TniB PF05621.11 CBK24456.2 - 2.1e-06 27.3 3.6 0.0024 17.3 0.1 4.2 3 1 0 3 3 3 1 Bacterial TniB protein Roc PF08477.13 CBK24456.2 - 2e-05 24.8 0.0 0.39 11.0 0.0 2.9 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase NACHT PF05729.12 CBK24456.2 - 3.7e-05 23.7 0.0 0.19 11.6 0.0 2.7 2 0 0 2 2 2 2 NACHT domain RuvB_N PF05496.12 CBK24456.2 - 6.3e-05 22.8 1.6 0.17 11.6 0.0 4.0 3 1 0 3 3 2 1 Holliday junction DNA helicase RuvB P-loop domain RNA_helicase PF00910.22 CBK24456.2 - 7.1e-05 23.1 0.1 0.37 11.2 0.0 3.5 4 0 0 4 4 2 1 RNA helicase AAA_28 PF13521.6 CBK24456.2 - 0.00017 21.9 0.8 1.4 9.1 0.0 4.0 4 0 0 4 4 3 1 AAA domain DUF815 PF05673.13 CBK24456.2 - 0.00023 20.4 0.1 0.03 13.5 0.0 2.7 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_25 PF13481.6 CBK24456.2 - 0.00037 20.1 0.0 0.14 11.7 0.0 3.1 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 CBK24456.2 - 0.00056 20.1 0.0 0.79 9.9 0.0 3.8 3 0 0 3 3 3 1 AAA domain RsgA_GTPase PF03193.16 CBK24456.2 - 0.00063 19.7 0.9 2.5 8.0 0.0 3.4 3 0 0 3 3 3 2 RsgA GTPase ATPase_2 PF01637.18 CBK24456.2 - 0.00084 19.3 15.8 0.62 9.9 0.1 5.3 4 1 2 6 6 4 3 ATPase domain predominantly from Archaea TsaE PF02367.17 CBK24456.2 - 0.0018 18.3 0.0 4.3 7.4 0.0 3.0 3 0 0 3 3 3 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Zeta_toxin PF06414.12 CBK24456.2 - 0.0018 17.6 0.0 0.14 11.4 0.0 2.8 2 0 0 2 2 2 1 Zeta toxin Mg_chelatase PF01078.21 CBK24456.2 - 0.0021 17.5 0.0 2.4 7.5 0.0 3.2 2 1 1 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_24 PF13479.6 CBK24456.2 - 0.0024 17.7 0.0 3.3 7.4 0.0 3.4 3 0 0 3 3 3 1 AAA domain ResIII PF04851.15 CBK24456.2 - 0.0036 17.3 0.0 0.33 10.9 0.0 3.7 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit AAA_3 PF07726.11 CBK24456.2 - 0.0044 16.9 0.0 4.2 7.2 0.0 3.5 3 1 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.6 CBK24456.2 - 0.013 15.3 0.0 0.37 10.6 0.0 2.8 2 0 0 2 2 2 0 DNA polymerase III, delta subunit AAA_18 PF13238.6 CBK24456.2 - 0.013 16.0 10.6 0.36 11.4 0.0 4.0 4 1 0 4 4 2 0 AAA domain T2SSE PF00437.20 CBK24456.2 - 0.017 14.2 0.1 0.052 12.6 0.1 2.0 1 1 0 1 1 1 0 Type II/IV secretion system protein AAA_19 PF13245.6 CBK24456.2 - 0.018 15.4 0.3 1.7 9.0 0.1 3.5 3 1 0 3 3 3 0 AAA domain AAA_23 PF13476.6 CBK24456.2 - 0.019 15.5 0.0 0.019 15.5 0.0 5.0 3 1 0 3 3 2 0 AAA domain NTPase_1 PF03266.15 CBK24456.2 - 0.019 14.9 1.0 5.9 6.8 0.0 3.0 3 0 0 3 3 2 0 NTPase PhoH PF02562.16 CBK24456.2 - 0.05 13.1 0.0 1 8.8 0.0 2.8 3 0 0 3 3 2 0 PhoH-like protein Laminin_II PF06009.12 CBK24456.2 - 0.059 13.4 6.7 0.26 11.3 6.7 2.1 1 0 0 1 1 1 0 Laminin Domain II SRP54 PF00448.22 CBK24456.2 - 0.072 12.7 7.9 0.35 10.5 0.0 3.7 4 0 0 4 4 4 0 SRP54-type protein, GTPase domain AAA_29 PF13555.6 CBK24456.2 - 0.1 12.3 0.0 22 4.9 0.0 2.6 2 0 0 2 2 2 0 P-loop containing region of AAA domain Ras PF00071.22 CBK24456.2 - 0.11 12.1 0.0 23 4.6 0.0 3.0 3 0 0 3 3 3 0 Ras family FTA4 PF13093.6 CBK24456.2 - 0.11 12.3 8.3 0.34 10.8 8.3 1.8 1 0 0 1 1 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 DUF87 PF01935.17 CBK24456.2 - 0.25 11.4 8.3 0.59 10.2 0.0 3.7 4 0 0 4 4 3 0 Helicase HerA, central domain Oscp1 PF10188.9 CBK24456.2 - 0.26 11.4 5.2 1.7 8.7 0.2 3.4 4 0 0 4 4 3 0 Organic solute transport protein 1 Exonuc_VII_L PF02601.15 CBK24456.2 - 4.2 6.8 13.5 6.7 6.2 10.0 2.3 2 0 0 2 2 2 0 Exonuclease VII, large subunit V_ATPase_I PF01496.19 CBK24456.2 - 9.5 4.0 11.4 5.2 4.8 9.4 1.5 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family Ank_5 PF13857.6 CBK24457.2 - 3.8e-10 39.8 0.4 2.4e-09 37.3 0.2 2.1 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 CBK24457.2 - 3.4e-09 36.2 0.3 6.1e-06 26.2 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.7 CBK24457.2 - 3.5e-08 33.9 0.2 5.5e-08 33.3 0.2 1.3 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CBK24457.2 - 1.2e-07 32.1 0.2 3.4e-07 30.7 0.1 1.8 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.30 CBK24457.2 - 4.5e-06 26.9 0.9 1.5e-05 25.2 0.1 2.2 2 0 0 2 2 2 1 Ankyrin repeat TatD_DNase PF01026.21 CBK24458.2 - 1.1e-46 159.3 0.0 1.3e-46 159.0 0.0 1.0 1 0 0 1 1 1 1 TatD related DNase Amidohydro_1 PF01979.20 CBK24458.2 - 0.00019 20.9 0.0 0.00024 20.5 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Actin PF00022.19 CBK24459.2 - 7.4e-88 294.9 0.0 1.6e-85 287.2 0.0 2.2 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.13 CBK24459.2 - 0.002 17.0 0.0 0.31 9.8 0.0 2.8 2 1 0 2 2 2 2 MreB/Mbl protein FtsA PF14450.6 CBK24459.2 - 0.081 13.4 0.0 1.9 9.0 0.0 2.7 2 1 0 2 2 2 0 Cell division protein FtsA LRR_5 PF13306.6 CBK24460.2 - 2.5e-24 85.7 147.5 2.8e-07 30.6 8.8 13.1 4 3 5 11 11 11 10 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 CBK24460.2 - 4.4e-15 55.2 97.3 2e-05 24.3 1.7 21.9 16 4 7 25 25 25 10 Leucine rich repeat LRR_9 PF14580.6 CBK24460.2 - 0.00013 21.5 29.9 0.52 9.8 0.1 10.6 7 4 5 12 12 12 4 Leucine-rich repeat hSac2 PF12456.8 CBK24460.2 - 0.00064 19.4 0.4 8.5 6.1 0.0 5.3 6 0 0 6 6 6 2 Inositol phosphatase He_PIG PF05345.12 CBK24463.2 - 1.3e-21 76.5 37.0 1.3e-05 25.3 1.2 6.6 6 0 0 6 6 6 5 Putative Ig domain DUF11 PF01345.18 CBK24463.2 - 0.00012 22.3 0.0 1.5 9.2 0.0 5.0 2 2 1 3 3 3 1 Domain of unknown function DUF11 I-set PF07679.16 CBK24463.2 - 0.00041 20.3 5.0 4.9 7.3 0.1 4.5 4 0 0 4 4 4 2 Immunoglobulin I-set domain HRM PF02793.22 CBK24463.2 - 0.058 13.7 10.8 8.4 6.8 0.1 5.2 5 0 0 5 5 5 0 Hormone receptor domain Phage_sheath_1N PF17481.2 CBK24463.2 - 2.4 8.7 6.3 30 5.1 0.1 3.6 3 0 0 3 3 3 0 Phage tail sheath protein beta-sandwich domain DUF3185 PF11381.8 CBK24463.2 - 6.7 6.8 8.7 22 5.1 8.7 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3185) Img2 PF05046.14 CBK24464.2 - 1.4e-13 50.9 0.0 2.5e-13 50.1 0.0 1.4 1 0 0 1 1 1 1 Mitochondrial large subunit ribosomal protein (Img2) SUI1 PF01253.22 CBK24464.2 - 5.8e-05 23.5 0.0 0.00011 22.7 0.0 1.4 1 0 0 1 1 1 1 Translation initiation factor SUI1 WD40 PF00400.32 CBK24466.2 - 1.5e-13 50.9 2.0 2.5e-06 28.1 0.3 4.1 4 0 0 4 4 4 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBK24466.2 - 1.7e-05 25.0 0.1 0.002 18.4 0.0 3.2 2 1 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain TFIID_NTD2 PF04494.15 CBK24466.2 - 0.0068 16.6 2.9 0.013 15.8 2.9 1.4 1 0 0 1 1 1 1 WD40 associated region in TFIID subunit, NTD2 domain Lgl_C PF08596.10 CBK24466.2 - 0.16 10.7 0.0 0.25 10.0 0.0 1.2 1 0 0 1 1 1 0 Lethal giant larvae(Lgl) like, C-terminal Carb_kinase PF01256.17 CBK24467.2 - 1.2e-49 169.0 0.0 1.6e-49 168.6 0.0 1.1 1 0 0 1 1 1 1 Carbohydrate kinase JAB PF01398.21 CBK24468.2 - 4.2e-32 110.6 0.1 6.2e-32 110.0 0.1 1.3 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.6 CBK24468.2 - 6.2e-06 26.0 0.0 1.2e-05 25.1 0.0 1.5 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain UPF0172 PF03665.13 CBK24468.2 - 0.046 13.8 0.0 0.074 13.1 0.0 1.4 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0172) DUF4329 PF14220.6 CBK24468.2 - 0.077 13.0 0.0 0.14 12.1 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4329) ORC3_N PF07034.11 CBK24468.2 - 0.2 10.7 0.0 8.3 5.4 0.0 2.1 2 0 0 2 2 2 0 Origin recognition complex (ORC) subunit 3 N-terminus Nop52 PF05997.12 CBK24469.2 - 3e-56 190.6 7.7 3.5e-56 190.4 7.7 1.1 1 0 0 1 1 1 1 Nucleolar protein,Nop52 Ribosomal_L6 PF00347.23 CBK24470.2 - 1.5e-27 96.1 3.9 1.1e-14 54.8 0.3 2.1 2 0 0 2 2 2 2 Ribosomal protein L6 Rota_VP4_MID PF17477.2 CBK24470.2 - 0.025 14.0 0.0 0.032 13.6 0.0 1.2 1 0 0 1 1 1 0 Rotavirus VP4 membrane interaction domain TPR_2 PF07719.17 CBK24471.2 - 2.8e-14 52.0 0.0 0.0018 18.2 0.0 4.6 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_1 PF00515.28 CBK24471.2 - 5.4e-13 48.2 0.0 0.00078 19.2 0.1 4.4 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_11 PF13414.6 CBK24471.2 - 8.2e-11 41.4 0.0 3.3e-06 26.7 0.0 2.8 2 1 1 3 3 3 2 TPR repeat TPR_14 PF13428.6 CBK24471.2 - 5.8e-09 36.0 0.0 0.18 12.7 0.0 5.4 4 1 2 6 6 5 3 Tetratricopeptide repeat TPR_8 PF13181.6 CBK24471.2 - 6.8e-08 32.1 0.0 0.65 10.4 0.0 3.8 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_19 PF14559.6 CBK24471.2 - 1.2e-06 28.9 0.0 0.058 13.9 0.0 4.1 3 2 1 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.6 CBK24471.2 - 1.7e-06 27.6 0.0 5 7.4 0.0 4.7 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.6 CBK24471.2 - 1.6e-05 25.5 0.0 0.024 15.3 0.0 3.9 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 CBK24471.2 - 3.2e-05 24.1 0.1 6.2 7.2 0.0 4.6 3 2 0 3 3 3 1 Tetratricopeptide repeat TPR_10 PF13374.6 CBK24471.2 - 0.00046 20.0 0.5 0.39 10.6 0.0 3.8 4 1 0 4 4 4 1 Tetratricopeptide repeat RPN7 PF10602.9 CBK24471.2 - 0.0013 18.4 0.8 7.3 6.3 0.0 4.5 2 2 3 5 5 5 1 26S proteasome subunit RPN7 ANAPC3 PF12895.7 CBK24471.2 - 0.016 15.4 0.1 27 5.1 0.0 3.3 2 1 1 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 PPR PF01535.20 CBK24471.2 - 0.067 13.5 0.2 32 5.1 0.0 3.7 3 1 1 4 4 3 0 PPR repeat TPR_17 PF13431.6 CBK24471.2 - 0.11 12.9 0.1 5.8 7.5 0.0 3.4 4 0 0 4 4 4 0 Tetratricopeptide repeat HSP90 PF00183.18 CBK24472.2 - 3.1e-102 343.1 10.3 5.7e-101 338.9 0.1 2.8 2 1 1 3 3 3 2 Hsp90 protein HATPase_c_3 PF13589.6 CBK24472.2 - 1.5e-12 47.6 0.2 3.7e-12 46.2 0.2 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 CBK24472.2 - 1.1e-09 38.7 0.1 2.1e-09 37.9 0.1 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Fibritin_C PF07921.12 CBK24472.2 - 0.019 15.0 0.3 0.053 13.6 0.3 1.7 1 0 0 1 1 1 0 Fibritin C-terminal region P5CR_dimer PF14748.6 CBK24472.2 - 0.098 12.9 0.2 29 5.0 0.0 3.2 3 0 0 3 3 3 0 Pyrroline-5-carboxylate reductase dimerisation Cytochrom_C PF00034.21 CBK24472.2 - 0.13 13.4 0.2 6.5 8.0 0.0 3.1 3 0 0 3 3 3 0 Cytochrome c Acyltransferase PF01553.21 CBK24473.2 - 5.3e-15 55.2 0.0 1e-14 54.3 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase Acyltransf_C PF16076.5 CBK24473.2 - 1.1e-08 35.0 0.5 3.3e-08 33.5 0.3 2.0 2 0 0 2 2 2 1 Acyltransferase C-terminus PDEase_I_N PF08499.12 CBK24473.2 - 0.046 13.6 0.7 0.26 11.2 0.4 2.2 2 0 0 2 2 2 0 3'5'-cyclic nucleotide phosphodiesterase N-terminal MORN_2 PF07661.13 CBK24474.2 - 0.36 11.2 0.0 0.36 11.2 0.0 3.5 4 0 0 4 4 4 0 MORN repeat variant MORN PF02493.20 CBK24475.2 - 0.064 13.2 7.7 1.5 8.9 3.1 2.7 2 0 0 2 2 2 0 MORN repeat ABC_tran PF00005.27 CBK24476.2 - 1.9e-38 132.1 0.0 7.4e-22 78.3 0.0 3.1 3 0 0 3 3 3 2 ABC transporter ABC2_membrane_3 PF12698.7 CBK24476.2 - 3.2e-22 79.1 26.7 5.2e-22 78.4 26.7 1.3 1 0 0 1 1 1 1 ABC-2 family transporter protein AAA_21 PF13304.6 CBK24476.2 - 4.6e-18 66.1 0.0 1.9e-05 24.6 0.0 3.4 3 0 0 3 3 3 3 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 CBK24476.2 - 1.8e-08 34.1 1.0 0.093 12.1 0.0 3.4 3 0 0 3 3 3 3 RecF/RecN/SMC N terminal domain YtpI PF14007.6 CBK24476.2 - 0.00013 22.1 2.5 0.0027 17.8 0.2 2.8 2 0 0 2 2 2 1 YtpI-like protein DUF4162 PF13732.6 CBK24476.2 - 0.00043 20.9 1.5 0.15 12.8 0.1 2.8 2 0 0 2 2 2 2 Domain of unknown function (DUF4162) SbcCD_C PF13558.6 CBK24476.2 - 0.0031 17.7 0.0 0.33 11.2 0.0 3.3 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_15 PF13175.6 CBK24476.2 - 0.024 14.4 0.9 1.5 8.4 0.5 3.2 3 0 0 3 3 3 0 AAA ATPase domain AAA PF00004.29 CBK24476.2 - 0.16 12.4 0.2 1.2 9.6 0.1 2.5 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) MASE5 PF17178.4 CBK24476.2 - 1.9 8.3 14.3 5.2 6.8 14.3 1.7 1 0 0 1 1 1 0 Membrane-associated sensor AAA_23 PF13476.6 CBK24476.2 - 3.1 8.3 10.6 1.5 9.3 6.5 2.5 2 1 0 2 2 2 0 AAA domain PA28_beta PF02252.18 CBK24477.2 - 1.6e-19 70.0 0.2 1.8e-10 40.7 0.3 2.4 1 1 1 2 2 2 2 Proteasome activator pa28 beta subunit PA28_alpha PF02251.18 CBK24477.2 - 0.01 15.9 2.1 0.047 13.7 0.1 2.3 2 0 0 2 2 2 0 Proteasome activator pa28 alpha subunit DUF2856 PF11043.8 CBK24477.2 - 0.13 12.4 0.1 1.8 8.7 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2856) ribosomal_L24 PF17136.4 CBK24478.2 - 2.1e-19 69.7 0.2 5.1e-19 68.4 0.0 1.7 2 0 0 2 2 2 1 Ribosomal proteins 50S L24/mitochondrial 39S L24 KOW PF00467.29 CBK24478.2 - 5.3e-07 29.4 2.5 1.1e-06 28.3 2.5 1.6 1 0 0 1 1 1 1 KOW motif Ribosomal_L3 PF00297.22 CBK24479.2 - 4.9e-175 581.9 9.5 5.6e-175 581.7 9.5 1.0 1 0 0 1 1 1 1 Ribosomal protein L3 Orf78 PF06024.12 CBK24480.2 - 0.00059 20.1 2.8 0.71 10.2 0.3 2.5 2 0 0 2 2 2 2 Orf78 (ac78) SUR7 PF06687.12 CBK24480.2 - 0.0044 16.7 0.0 0.0078 15.9 0.0 1.4 1 0 0 1 1 1 1 SUR7/PalI family DUF5305 PF17231.2 CBK24480.2 - 0.0091 15.4 1.2 0.26 10.7 0.1 2.3 2 0 0 2 2 2 1 Family of unknown function (DUF5305) DUF3899 PF13038.6 CBK24480.2 - 0.01 16.3 0.4 4.4 7.9 0.1 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3899) FAM176 PF14851.6 CBK24480.2 - 0.018 14.7 2.1 0.019 14.6 0.2 2.0 1 1 1 2 2 2 0 FAM176 family FtsX PF02687.21 CBK24480.2 - 0.037 14.5 3.2 0.084 13.3 3.1 1.6 1 1 0 1 1 1 0 FtsX-like permease family EI24 PF07264.11 CBK24480.2 - 0.15 12.3 2.7 0.25 11.6 2.7 1.2 1 0 0 1 1 1 0 Etoposide-induced protein 2.4 (EI24) Shisa PF13908.6 CBK24480.2 - 0.69 10.1 6.1 0.32 11.2 0.3 2.2 1 1 1 2 2 2 0 Wnt and FGF inhibitory regulator DUF4519 PF15012.6 CBK24480.2 - 0.8 9.9 0.0 0.8 9.9 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4519) TA_inhibitor PF17574.2 CBK24481.2 - 3.8e-21 74.9 0.0 0.0015 18.5 0.0 6.7 8 0 0 8 8 8 5 Inhibitor of toxin/antitoxin system (Gp4.5) IRF-2BP1_2 PF11261.8 CBK24481.2 - 0.0018 17.8 1.3 1.6e+02 2.0 0.0 5.6 5 0 0 5 5 5 0 Interferon regulatory factor 2-binding protein zinc finger POLO_box PF00659.18 CBK24481.2 - 0.028 14.6 0.2 1.1e+02 3.1 0.0 4.2 4 0 0 4 4 4 0 POLO box duplicated region DUF5431 PF17496.2 CBK24481.2 - 0.08 13.1 7.8 1.7e+02 2.5 0.0 5.1 5 0 0 5 5 5 0 Family of unknown function (DUF5431) DUF2158 PF09926.9 CBK24481.2 - 1.3 8.8 22.1 47 3.8 0.1 7.3 8 0 0 8 8 8 0 Uncharacterized small protein (DUF2158) AAA PF00004.29 CBK24482.2 - 1e-55 187.7 0.0 3.2e-41 140.8 0.0 2.9 2 1 1 3 3 3 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CBK24482.2 - 2.3e-11 43.3 0.0 6.6e-11 41.8 0.0 1.8 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 CBK24482.2 - 2.3e-08 34.6 0.0 0.00026 21.4 0.0 2.9 2 1 0 2 2 2 2 AAA ATPase domain RuvB_N PF05496.12 CBK24482.2 - 1.5e-07 31.3 0.1 0.01 15.6 0.0 3.9 4 0 0 4 4 4 2 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 CBK24482.2 - 1.4e-06 28.4 0.1 0.0018 18.3 0.1 2.9 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_14 PF13173.6 CBK24482.2 - 1.5e-06 28.2 0.0 0.028 14.5 0.0 2.7 3 0 0 3 3 2 2 AAA domain AAA_22 PF13401.6 CBK24482.2 - 3.1e-06 27.5 0.8 0.0057 16.9 0.0 3.9 2 2 1 3 3 3 1 AAA domain AAA_2 PF07724.14 CBK24482.2 - 4.1e-06 27.0 0.0 6.6e-05 23.1 0.0 2.3 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) RNA_helicase PF00910.22 CBK24482.2 - 4.8e-06 26.9 0.0 0.0098 16.3 0.0 2.9 2 0 0 2 2 2 2 RNA helicase NACHT PF05729.12 CBK24482.2 - 9.2e-06 25.7 0.5 0.6 10.0 0.0 3.6 4 0 0 4 4 4 2 NACHT domain AAA_18 PF13238.6 CBK24482.2 - 1.2e-05 25.8 0.0 0.063 13.8 0.0 2.6 2 0 0 2 2 2 2 AAA domain ATPase_2 PF01637.18 CBK24482.2 - 3.4e-05 23.9 0.2 0.33 10.8 0.2 4.1 3 1 1 4 4 4 1 ATPase domain predominantly from Archaea IstB_IS21 PF01695.17 CBK24482.2 - 5e-05 23.1 0.0 0.2 11.4 0.0 2.5 2 0 0 2 2 2 2 IstB-like ATP binding protein TsaE PF02367.17 CBK24482.2 - 7.5e-05 22.7 0.0 0.097 12.7 0.0 2.4 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE ABC_tran PF00005.27 CBK24482.2 - 8.1e-05 23.2 0.1 0.005 17.4 0.0 2.7 2 0 0 2 2 2 1 ABC transporter TIP49 PF06068.13 CBK24482.2 - 0.00016 21.0 0.0 0.053 12.7 0.0 2.2 2 0 0 2 2 2 1 TIP49 P-loop domain AAA_33 PF13671.6 CBK24482.2 - 0.0003 21.0 0.0 0.07 13.3 0.0 2.4 2 0 0 2 2 2 1 AAA domain Sigma54_activat PF00158.26 CBK24482.2 - 0.0004 20.1 0.0 1 9.0 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_28 PF13521.6 CBK24482.2 - 0.00053 20.3 0.0 0.26 11.5 0.0 2.6 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.21 CBK24482.2 - 0.00094 18.6 0.3 0.01 15.2 0.1 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI NB-ARC PF00931.22 CBK24482.2 - 0.0012 18.1 0.0 0.2 10.8 0.0 2.3 2 0 0 2 2 2 1 NB-ARC domain ATPase PF06745.13 CBK24482.2 - 0.0014 18.1 0.0 0.012 15.0 0.0 2.3 2 0 0 2 2 2 1 KaiC AAA_24 PF13479.6 CBK24482.2 - 0.0017 18.1 0.0 0.12 12.1 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.6 CBK24482.2 - 0.0035 17.8 0.0 2.1 8.8 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 CBK24482.2 - 0.0046 16.5 0.0 0.05 13.1 0.0 2.1 2 0 0 2 2 2 1 P-loop containing dynein motor region Rad17 PF03215.15 CBK24482.2 - 0.0061 16.5 0.0 0.083 12.8 0.0 2.4 2 1 0 2 2 2 1 Rad17 P-loop domain Zeta_toxin PF06414.12 CBK24482.2 - 0.0079 15.5 0.0 5.3 6.3 0.0 2.8 2 0 0 2 2 2 1 Zeta toxin AAA_25 PF13481.6 CBK24482.2 - 0.025 14.1 3.4 2.5 7.6 0.0 3.8 2 2 0 4 4 4 0 AAA domain AAA_3 PF07726.11 CBK24482.2 - 0.034 14.0 0.0 0.83 9.5 0.0 2.7 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 CBK24482.2 - 0.047 13.1 0.0 6.7 6.1 0.0 2.3 2 0 0 2 2 2 0 PhoH-like protein DUF3219 PF11514.8 CBK24482.2 - 0.074 13.1 0.4 15 5.6 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3219) TniB PF05621.11 CBK24482.2 - 0.12 11.7 0.2 4.2 6.7 0.0 2.8 2 1 1 3 3 3 0 Bacterial TniB protein SKI PF01202.22 CBK24482.2 - 0.14 12.3 0.0 20 5.3 0.0 2.5 2 0 0 2 2 2 0 Shikimate kinase Jnk-SapK_ap_N PF09744.9 CBK24483.2 - 0.0087 16.3 8.3 0.012 15.9 8.3 1.3 1 0 0 1 1 1 1 JNK_SAPK-associated protein-1 HAUS6_N PF14661.6 CBK24483.2 - 0.015 14.9 4.0 0.019 14.6 4.0 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus SOGA PF11365.8 CBK24483.2 - 0.04 15.1 7.2 0.046 14.9 1.1 2.4 2 1 0 2 2 2 0 Protein SOGA Takusan PF04822.13 CBK24483.2 - 0.045 13.6 0.6 0.045 13.6 0.6 2.2 2 0 0 2 2 2 0 Takusan CENP-Q PF13094.6 CBK24483.2 - 0.065 13.4 9.6 0.082 13.1 9.6 1.1 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit Fib_alpha PF08702.10 CBK24483.2 - 0.076 13.2 6.4 0.11 12.7 6.4 1.1 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family CCDC106 PF15794.5 CBK24483.2 - 0.085 12.6 7.9 0.11 12.1 7.9 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 GAS PF13851.6 CBK24483.2 - 0.11 11.8 11.7 0.032 13.6 5.6 2.0 1 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding Ldt_C PF17969.1 CBK24483.2 - 0.25 12.1 2.1 0.52 11.1 1.2 2.0 1 1 1 2 2 2 0 L,D-transpeptidase C-terminal domain FapA PF03961.13 CBK24483.2 - 0.42 9.2 4.7 0.55 8.8 4.7 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A DivIC PF04977.15 CBK24483.2 - 2.3 8.1 7.9 1.2 9.0 4.1 2.1 2 0 0 2 2 2 0 Septum formation initiator TMPIT PF07851.13 CBK24483.2 - 3 7.0 7.3 3.8 6.7 7.3 1.1 1 0 0 1 1 1 0 TMPIT-like protein APG6_N PF17675.1 CBK24483.2 - 3.3 8.2 15.7 3.4 8.2 8.5 2.1 1 1 1 2 2 2 0 Apg6 coiled-coil region DUF4337 PF14235.6 CBK24483.2 - 4.9 7.2 5.6 20 5.2 4.4 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4337) Tim17 PF02466.19 CBK24484.2 - 0.041 14.3 0.5 0.083 13.3 0.5 1.4 1 0 0 1 1 1 0 Tim17/Tim22/Tim23/Pmp24 family Ssu72 PF04722.13 CBK24485.2 - 9.9e-52 175.3 0.0 1.2e-51 175.0 0.0 1.0 1 0 0 1 1 1 1 Ssu72-like protein MMACHC PF16690.5 CBK24486.2 - 7.4e-10 38.8 0.4 1.4e-07 31.4 0.4 2.3 1 1 0 1 1 1 1 Methylmalonic aciduria and homocystinuria type C family COG4 PF08318.12 CBK24487.2 - 6e-67 226.1 2.2 8.4e-67 225.6 2.2 1.1 1 0 0 1 1 1 1 COG4 transport protein FTR_C PF02741.15 CBK24487.2 - 0.049 13.6 0.0 0.13 12.3 0.0 1.7 1 0 0 1 1 1 0 FTR, proximal lobe Sec10 PF07393.11 CBK24488.2 - 0.0022 16.5 0.3 0.0024 16.4 0.3 1.0 1 0 0 1 1 1 1 Exocyst complex component Sec10 LIAS_N PF16881.5 CBK24489.2 - 3.2e-22 79.0 0.1 7.4e-22 77.8 0.1 1.6 1 0 0 1 1 1 1 N-terminal domain of lipoyl synthase of Radical_SAM family Radical_SAM PF04055.21 CBK24489.2 - 5.4e-12 46.4 0.5 1.2e-11 45.2 0.3 1.7 2 0 0 2 2 2 1 Radical SAM superfamily Toxin_21 PF08091.11 CBK24489.2 - 0.48 10.4 3.9 1.3 9.0 3.9 1.7 1 0 0 1 1 1 0 Spider insecticidal peptide Actin PF00022.19 CBK24490.2 - 4.7e-88 295.5 0.0 9.6e-86 287.9 0.0 2.2 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.13 CBK24490.2 - 0.0019 17.1 0.0 0.31 9.8 0.0 2.8 2 1 0 2 2 2 2 MreB/Mbl protein FtsA PF14450.6 CBK24490.2 - 0.08 13.4 0.0 2.1 8.8 0.0 2.7 2 1 0 2 2 2 0 Cell division protein FtsA Ribosomal_S8e PF01201.22 CBK24491.2 - 3.4e-35 121.2 0.1 4.4e-35 120.8 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein S8e Pan3_PK PF18101.1 CBK24492.2 - 2.3e-47 160.5 0.0 2.9e-47 160.1 0.0 1.1 1 0 0 1 1 1 1 Pan3 Pseudokinase domain S-AdoMet_synt_M PF02772.16 CBK24492.2 - 0.11 12.8 0.0 2.7 8.3 0.0 2.1 2 0 0 2 2 2 0 S-adenosylmethionine synthetase, central domain DUF608 PF04685.13 CBK24492.2 - 0.12 11.5 0.0 0.98 8.5 0.0 1.9 2 0 0 2 2 2 0 Glycosyl-hydrolase family 116, catalytic region PFK PF00365.20 CBK24494.2 - 4.3e-40 137.8 0.0 4.9e-38 131.1 0.0 2.2 2 0 0 2 2 2 2 Phosphofructokinase Helicase_C_3 PF13625.6 CBK24494.2 - 0.16 12.1 0.0 0.32 11.1 0.0 1.4 1 0 0 1 1 1 0 Helicase conserved C-terminal domain EGF_2 PF07974.13 CBK24496.2 - 3.7e-16 59.2 92.0 0.00014 22.2 9.3 6.8 6 1 0 6 6 6 5 EGF-like domain EGF PF00008.27 CBK24496.2 - 1.6e-08 34.6 72.2 0.00081 19.6 6.5 6.7 6 0 0 6 6 6 6 EGF-like domain DSL PF01414.19 CBK24496.2 - 4e-05 23.8 68.5 0.00037 20.7 20.6 5.2 1 1 5 6 6 6 4 Delta serrate ligand Laminin_EGF PF00053.24 CBK24496.2 - 0.0017 18.5 79.6 0.79 9.9 11.9 6.3 2 2 4 6 6 6 4 Laminin EGF domain Lyase_1 PF00206.20 CBK24497.2 - 4.2e-24 85.5 0.0 7e-24 84.8 0.0 1.4 1 0 0 1 1 1 1 Lyase ADSL_C PF10397.9 CBK24497.2 - 1.8e-17 63.6 0.0 4.4e-17 62.4 0.0 1.7 1 0 0 1 1 1 1 Adenylosuccinate lyase C-terminus Mito_carr PF00153.27 CBK24498.2 - 2.2e-10 40.3 0.1 2.9e-10 39.9 0.1 1.2 1 0 0 1 1 1 1 Mitochondrial carrier protein Mito_carr PF00153.27 CBK24499.2 - 3.3e-18 65.4 0.2 3.6e-10 39.6 0.1 2.4 2 1 0 2 2 2 2 Mitochondrial carrier protein DUF4834 PF16118.5 CBK24500.2 - 0.16 13.0 7.6 0.62 11.1 7.6 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4834) Ctr PF04145.15 CBK24500.2 - 0.23 12.1 0.7 0.29 11.7 0.7 1.3 1 0 0 1 1 1 0 Ctr copper transporter family Presenilin PF01080.17 CBK24500.2 - 0.95 8.2 6.7 1.1 7.9 6.7 1.0 1 0 0 1 1 1 0 Presenilin RSRP PF17069.5 CBK24500.2 - 1.9 8.0 34.0 2.2 7.8 34.0 1.1 1 0 0 1 1 1 0 Arginine/Serine-Rich protein 1 HRM PF02793.22 CBK24501.2 - 0.013 15.8 0.5 0.02 15.2 0.5 1.4 1 0 0 1 1 1 0 Hormone receptor domain WBP-1 PF11669.8 CBK24501.2 - 0.015 15.9 0.3 0.023 15.3 0.3 1.3 1 0 0 1 1 1 0 WW domain-binding protein 1 Glycoprotein_G PF00802.19 CBK24501.2 - 0.03 13.7 0.4 0.038 13.3 0.4 1.2 1 0 0 1 1 1 0 Pneumovirus attachment glycoprotein G Spore_YhaL PF14147.6 CBK24501.2 - 0.049 13.3 0.1 0.071 12.8 0.1 1.3 1 0 0 1 1 1 0 Sporulation protein YhaL Phi-29_GP16_7 PF06720.11 CBK24501.2 - 0.086 12.7 0.2 0.11 12.3 0.2 1.2 1 0 0 1 1 1 0 Bacteriophage phi-29 early protein GP16.7 EphA2_TM PF14575.6 CBK24501.2 - 0.11 13.4 1.4 0.17 12.8 1.4 1.2 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain RICTOR_V PF14668.6 CBK24502.2 - 6.1e-16 58.4 0.2 4.6e-15 55.6 0.2 2.3 2 0 0 2 2 2 1 Rapamycin-insensitive companion of mTOR, domain 5 RICTOR_N PF14664.6 CBK24503.2 - 2.3e-27 96.0 4.8 3.2e-27 95.5 4.8 1.2 1 0 0 1 1 1 1 Rapamycin-insensitive companion of mTOR, N-term Acetyltransf_1 PF00583.25 CBK24504.2 - 0.00023 21.4 0.0 0.00033 20.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 CBK24504.2 - 0.00055 19.9 0.0 0.0007 19.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 CBK24504.2 - 0.13 12.2 0.0 0.23 11.5 0.0 1.3 1 0 0 1 1 1 0 FR47-like protein Choline_transpo PF04515.12 CBK24505.2 - 1e-79 268.1 35.9 1.2e-79 267.9 35.9 1.0 1 0 0 1 1 1 1 Plasma-membrane choline transporter DUF3382 PF11862.8 CBK24505.2 - 0.023 15.0 0.4 0.1 12.9 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3382) Phage_holin_2_4 PF16082.5 CBK24505.2 - 0.14 11.9 0.1 0.47 10.2 0.1 1.9 1 0 0 1 1 1 0 Bacteriophage holin family, superfamily II-like PAC4 PF16093.5 CBK24505.2 - 0.46 10.7 2.9 41 4.5 0.0 3.4 3 0 0 3 3 3 0 Proteasome assembly chaperone 4 Methyltransf_4 PF02390.17 CBK24506.2 - 3.7e-34 117.7 0.0 4.9e-34 117.3 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase PCMT PF01135.19 CBK24506.2 - 0.00027 20.8 0.0 0.00037 20.3 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_25 PF13649.6 CBK24506.2 - 0.0011 19.6 0.0 0.0017 19.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 CBK24506.2 - 0.0013 18.8 0.0 0.0017 18.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 CBK24506.2 - 0.0017 17.9 0.0 0.0023 17.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_31 PF13847.6 CBK24506.2 - 0.0041 16.9 0.0 0.0055 16.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain CheR PF01739.18 CBK24506.2 - 0.0054 16.2 0.0 0.0081 15.7 0.0 1.2 1 0 0 1 1 1 1 CheR methyltransferase, SAM binding domain Zds_C PF08632.10 CBK24506.2 - 0.011 15.5 0.1 0.023 14.5 0.1 1.4 1 0 0 1 1 1 0 Activator of mitotic machinery Cdc14 phosphatase activation C-term RrnaAD PF00398.20 CBK24506.2 - 0.014 14.5 0.0 0.017 14.2 0.0 1.1 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Methyltransf_23 PF13489.6 CBK24506.2 - 0.083 12.7 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Ubie_methyltran PF01209.18 CBK24506.2 - 0.089 12.1 0.0 0.14 11.5 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.12 CBK24506.2 - 0.19 12.4 0.0 0.31 11.7 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain PrmA PF06325.13 CBK24506.2 - 0.23 10.8 0.2 0.41 10.0 0.1 1.4 1 1 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Kdo_hydroxy PF11004.8 CBK24507.2 - 0.017 14.4 0.3 0.019 14.2 0.3 1.1 1 0 0 1 1 1 0 3-deoxy-D-manno-oct-2-ulosonic acid (Kdo) hydroxylase NRDE-2 PF08424.10 CBK24508.2 - 3.6e-05 23.1 0.0 3.6e-05 23.1 0.0 3.4 3 1 1 4 4 3 1 NRDE-2, necessary for RNA interference TPR_14 PF13428.6 CBK24508.2 - 0.0005 20.7 0.5 2.9e+02 2.7 0.0 6.8 4 3 4 8 8 8 0 Tetratricopeptide repeat TPR_17 PF13431.6 CBK24508.2 - 0.0049 17.2 0.0 2.3 8.8 0.0 3.6 2 0 0 2 2 2 1 Tetratricopeptide repeat Suf PF05843.14 CBK24508.2 - 0.49 10.3 0.0 0.49 10.3 0.0 3.9 3 1 0 3 3 2 0 Suppressor of forked protein (Suf) PIP5K PF01504.18 CBK24508.2 - 0.68 9.1 7.4 1.2 8.3 7.4 1.3 1 0 0 1 1 1 0 Phosphatidylinositol-4-phosphate 5-Kinase CCDC53 PF10152.9 CBK24508.2 - 0.76 10.2 11.9 1.7 9.1 11.9 1.5 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex FHIPEP PF00771.20 CBK24508.2 - 1.6 7.1 5.9 2.2 6.6 5.9 1.1 1 0 0 1 1 1 0 FHIPEP family Velvet PF11754.8 CBK24508.2 - 2.4 8.1 13.4 3.8 7.4 13.4 1.2 1 0 0 1 1 1 0 Velvet factor GET2 PF08690.10 CBK24508.2 - 4.3 6.9 26.7 7.4 6.1 26.7 1.3 1 0 0 1 1 1 0 GET complex subunit GET2 TPR_6 PF13174.6 CBK24508.2 - 4.5 8.1 13.5 39 5.2 0.0 6.6 7 0 0 7 7 7 0 Tetratricopeptide repeat Presenilin PF01080.17 CBK24508.2 - 4.6 5.9 12.0 7 5.3 12.0 1.2 1 0 0 1 1 1 0 Presenilin ALMT PF11744.8 CBK24508.2 - 5.7 5.7 9.1 9.1 5.0 9.1 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter TFIIA PF03153.13 CBK24508.2 - 8.2 6.3 32.6 12 5.7 32.6 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit ERCC3_RAD25_C PF16203.5 CBK24509.2 - 4.1e-91 304.6 0.0 6.6e-91 303.9 0.0 1.3 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase Helicase_C_3 PF13625.6 CBK24509.2 - 9.2e-23 80.8 0.0 1.7e-22 79.9 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 CBK24509.2 - 1.4e-15 57.7 0.0 2.7e-15 56.8 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 CBK24509.2 - 6e-10 39.4 0.5 4.7e-09 36.6 0.0 2.7 3 0 0 3 3 3 1 Helicase conserved C-terminal domain SNF2_N PF00176.23 CBK24509.2 - 0.00022 20.1 0.0 0.00036 19.4 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain DEAD PF00270.29 CBK24509.2 - 0.0013 18.6 0.0 0.0028 17.5 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase IlvC PF01450.19 CBK24509.2 - 0.031 14.6 0.5 0.073 13.4 0.5 1.6 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain B56 PF01603.20 CBK24510.2 - 6.6e-15 55.0 4.0 1.2e-14 54.1 4.0 1.4 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) DUF922 PF06037.11 CBK24510.2 - 0.043 13.6 0.0 0.17 11.7 0.1 1.8 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF922) Glycos_transf_1 PF00534.20 CBK24511.2 - 1.3e-27 96.4 0.0 2.2e-27 95.7 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 CBK24511.2 - 4.6e-20 72.3 0.0 7.8e-20 71.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_1_4 PF13692.6 CBK24511.2 - 1.6e-16 61.0 0.0 1.8e-15 57.6 0.0 2.1 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 CBK24511.2 - 3.8e-10 40.4 0.0 1.1e-09 38.9 0.0 1.7 1 1 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.6 CBK24511.2 - 0.00015 22.0 0.0 0.00031 21.1 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 NmrA PF05368.13 CBK24511.2 - 0.0051 16.4 0.0 0.0089 15.6 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family Glyco_trans_4_2 PF13477.6 CBK24511.2 - 0.097 12.7 0.0 0.38 10.8 0.0 2.1 2 1 0 2 2 2 0 Glycosyl transferase 4-like DDE_Tnp_ISAZ013 PF07592.11 CBK24511.2 - 0.15 11.0 0.0 2.4 7.1 0.0 2.1 2 0 0 2 2 2 0 Rhodopirellula transposase DDE domain adh_short_C2 PF13561.6 CBK24512.2 - 1.8e-42 145.5 1.8 2.1e-41 142.0 1.8 1.9 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 CBK24512.2 - 4.5e-39 133.9 1.9 2.9e-38 131.3 1.9 1.9 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 CBK24512.2 - 1.5e-07 31.5 0.3 2.1e-07 31.1 0.3 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 CBK24512.2 - 0.018 14.5 0.0 0.027 13.9 0.0 1.4 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family DUF1776 PF08643.10 CBK24512.2 - 0.037 13.4 0.0 0.18 11.1 0.0 1.8 2 0 0 2 2 2 0 Fungal family of unknown function (DUF1776) Methyltransf_28 PF02636.17 CBK24513.2 - 7.9e-09 35.5 0.0 2.4e-08 33.9 0.0 1.8 1 1 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase MRG PF05712.13 CBK24514.2 - 4.1e-19 68.7 6.7 7.8e-19 67.8 6.7 1.5 1 1 0 1 1 1 1 MRG Tudor-knot PF11717.8 CBK24514.2 - 2.2e-08 33.8 0.5 5.5e-08 32.6 0.5 1.7 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Chromo PF00385.24 CBK24514.2 - 0.024 14.6 0.4 0.12 12.3 0.2 2.3 2 0 0 2 2 2 0 Chromo (CHRromatin Organisation MOdifier) domain Snf7 PF03357.21 CBK24515.2 - 1.1e-26 93.5 8.5 1.5e-26 93.0 8.5 1.1 1 0 0 1 1 1 1 Snf7 GED PF02212.18 CBK24515.2 - 0.11 12.7 3.9 0.22 11.7 0.1 2.6 2 1 0 2 2 2 0 Dynamin GTPase effector domain GalKase_gal_bdg PF10509.9 CBK24516.2 - 4.9e-22 77.2 0.1 9.2e-22 76.4 0.1 1.5 1 0 0 1 1 1 1 Galactokinase galactose-binding signature GHMP_kinases_N PF00288.26 CBK24516.2 - 4.4e-11 42.9 3.6 1.2e-10 41.5 3.6 1.8 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 CBK24516.2 - 1.4e-10 41.4 0.6 1.8e-09 37.8 0.6 2.7 1 1 0 1 1 1 1 GHMP kinases C terminal Adaptin_N PF01602.20 CBK24517.2 - 1.6e-74 251.4 1.3 2e-74 251.0 1.3 1.1 1 0 0 1 1 1 1 Adaptin N terminal region COP-gamma_platf PF08752.10 CBK24517.2 - 3.3e-34 118.2 0.0 7.4e-34 117.1 0.0 1.6 1 0 0 1 1 1 1 Coatomer gamma subunit appendage platform subdomain Coatomer_g_Cpla PF16381.5 CBK24517.2 - 5.3e-32 110.4 0.0 2.9e-31 108.0 0.0 2.1 2 0 0 2 2 2 1 Coatomer subunit gamma-1 C-terminal appendage platform Cnd1 PF12717.7 CBK24517.2 - 9.7e-08 32.2 4.5 0.031 14.3 0.2 4.3 2 1 2 4 4 4 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 CBK24517.2 - 1.1e-06 29.0 12.4 0.00017 21.9 2.1 5.3 3 2 3 6 6 6 3 HEAT repeats HEAT PF02985.22 CBK24517.2 - 0.0026 17.9 16.3 1.7 9.1 0.1 6.1 5 0 0 5 5 5 2 HEAT repeat AbiJ_NTD5 PF18865.1 CBK24517.2 - 0.015 15.1 0.4 0.095 12.5 0.1 2.5 2 0 0 2 2 2 0 AbiJ N-terminal domain 5 Arm PF00514.23 CBK24517.2 - 0.21 11.7 1.3 4 7.6 0.0 3.7 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat HEAT_PBS PF03130.16 CBK24517.2 - 0.54 11.1 5.5 3.9 8.4 2.0 3.9 2 1 1 3 3 3 0 PBS lyase HEAT-like repeat HEAT_EZ PF13513.6 CBK24517.2 - 1.2 9.8 25.9 0.047 14.2 4.5 6.4 7 1 1 8 8 8 0 HEAT-like repeat RGS PF00615.19 CBK24518.2 - 2.3e-06 27.8 0.2 2.7e-06 27.6 0.2 1.1 1 0 0 1 1 1 1 Regulator of G protein signaling domain DUF4707 PF15806.5 CBK24519.2 - 2.4 7.0 4.8 3.2 6.6 4.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4707) Methyltr_RsmB-F PF01189.17 CBK24520.2 - 4.9e-17 62.2 0.0 5.3e-17 62.1 0.0 1.0 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F Methyltransf_31 PF13847.6 CBK24520.2 - 0.004 17.0 0.0 0.0068 16.2 0.0 1.2 1 1 0 1 1 1 1 Methyltransferase domain RrnaAD PF00398.20 CBK24520.2 - 0.011 14.8 0.0 0.013 14.6 0.0 1.1 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase FtsJ PF01728.19 CBK24520.2 - 0.062 13.4 0.0 0.076 13.1 0.0 1.1 1 0 0 1 1 1 0 FtsJ-like methyltransferase Ubie_methyltran PF01209.18 CBK24520.2 - 0.12 11.7 0.0 0.14 11.4 0.0 1.1 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family MutS_V PF00488.21 CBK24521.2 - 1.6e-68 230.5 0.1 4.6e-68 229.0 0.0 1.8 2 0 0 2 2 2 1 MutS domain V MutS_III PF05192.18 CBK24521.2 - 5.3e-36 124.6 0.3 1.5e-35 123.1 0.2 1.9 2 0 0 2 2 2 1 MutS domain III MutS_I PF01624.20 CBK24521.2 - 1.6e-30 105.6 0.2 3.2e-30 104.7 0.2 1.5 1 0 0 1 1 1 1 MutS domain I MutS_IV PF05190.18 CBK24521.2 - 4.3e-11 43.0 0.1 1.3e-10 41.5 0.1 1.9 1 0 0 1 1 1 1 MutS family domain IV MutS_II PF05188.17 CBK24521.2 - 1.2e-07 32.1 0.2 8.3e-06 26.1 0.0 3.1 2 1 0 2 2 2 1 MutS domain II DUF2400 PF09674.10 CBK24521.2 - 0.0092 16.0 0.1 0.025 14.6 0.1 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF2400) AAA_27 PF13514.6 CBK24521.2 - 0.022 14.3 0.0 0.11 12.1 0.0 2.1 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 CBK24521.2 - 0.051 14.1 0.5 15 6.1 0.2 2.8 2 0 0 2 2 2 0 ABC transporter AAA_14 PF13173.6 CBK24521.2 - 0.094 12.8 0.0 0.36 10.9 0.0 2.0 1 0 0 1 1 1 0 AAA domain CLAMP PF14769.6 CBK24521.2 - 0.68 10.4 4.1 1.2 9.7 1.1 2.5 2 0 0 2 2 2 0 Flagellar C1a complex subunit C1a-32 Tax PF02959.16 CBK24523.2 - 0.019 14.4 0.0 0.89 9.0 0.0 2.2 2 0 0 2 2 2 0 HTLV Tax FAS_N PF17828.1 CBK24523.2 - 0.023 14.7 0.1 0.078 13.0 0.0 1.9 2 0 0 2 2 2 0 N-terminal domain in fatty acid synthase subunit beta GAIN_A PF18619.1 CBK24523.2 - 0.094 12.9 0.1 0.31 11.3 0.1 1.9 1 0 0 1 1 1 0 GPCR-Autoproteolysis-INducing (GAIN) subdomain A Sec1 PF00995.23 CBK24524.2 - 6.6e-104 349.2 0.0 7.7e-104 349.0 0.0 1.0 1 0 0 1 1 1 1 Sec1 family GTP_EFTU PF00009.27 CBK24525.2 - 2.4e-17 63.1 0.0 5.9e-17 61.8 0.0 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 CBK24525.2 - 2.9e-07 30.6 0.0 5.7e-07 29.6 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Ras PF00071.22 CBK24525.2 - 8.4e-05 22.2 0.0 0.00014 21.5 0.0 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CBK24525.2 - 8.9e-05 22.7 0.0 0.00014 22.0 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase PduV-EutP PF10662.9 CBK24525.2 - 0.0011 18.7 0.2 0.026 14.3 0.2 2.2 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation Septin PF00735.18 CBK24525.2 - 0.0014 17.9 0.0 0.18 11.0 0.0 2.2 2 0 0 2 2 2 2 Septin RsgA_GTPase PF03193.16 CBK24525.2 - 0.0017 18.3 0.0 0.033 14.1 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase ATP_bind_1 PF03029.17 CBK24525.2 - 0.02 14.7 0.0 0.074 12.8 0.0 1.9 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Arf PF00025.21 CBK24525.2 - 0.036 13.5 0.1 0.26 10.7 0.0 2.0 2 0 0 2 2 2 0 ADP-ribosylation factor family Dynamin_N PF00350.23 CBK24525.2 - 0.097 12.7 0.0 2.8 8.0 0.0 2.4 1 1 1 2 2 2 0 Dynamin family NadA PF02445.16 CBK24525.2 - 0.18 10.9 0.0 0.29 10.3 0.0 1.2 1 0 0 1 1 1 0 Quinolinate synthetase A protein C2 PF00168.30 CBK24527.2 - 6.1e-18 65.0 0.0 1.3e-17 64.0 0.0 1.6 1 0 0 1 1 1 1 C2 domain YbjQ_1 PF01906.17 CBK24527.2 - 0.018 15.7 0.0 0.033 14.8 0.0 1.5 1 0 0 1 1 1 0 Putative heavy-metal-binding Isochorismatase PF00857.20 CBK24528.2 - 1.7e-29 103.2 0.4 2.3e-29 102.8 0.4 1.2 1 0 0 1 1 1 1 Isochorismatase family HSF_DNA-bind PF00447.17 CBK24529.2 - 7.3e-25 87.4 0.5 1.5e-24 86.4 0.5 1.5 1 0 0 1 1 1 1 HSF-type DNA-binding S1 PF00575.23 CBK24529.2 - 3.5e-08 33.7 0.1 6.8e-08 32.7 0.1 1.5 1 0 0 1 1 1 1 S1 RNA binding domain Suf PF05843.14 CBK24529.2 - 5.7e-07 29.8 6.3 0.00044 20.3 0.2 3.5 4 0 0 4 4 4 2 Suppressor of forked protein (Suf) TPR_19 PF14559.6 CBK24529.2 - 8.2e-06 26.2 0.7 0.37 11.3 0.2 3.9 2 1 2 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 CBK24529.2 - 9.1e-05 23.0 13.9 0.0025 18.5 1.8 4.7 1 1 4 5 5 5 1 Tetratricopeptide repeat Collagen PF01391.18 CBK24529.2 - 0.00045 19.9 11.1 0.00079 19.1 11.1 1.3 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) TPR_12 PF13424.6 CBK24529.2 - 0.0086 16.4 2.3 1.9 8.8 1.1 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.6 CBK24529.2 - 0.017 15.8 0.1 3.9 8.3 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 CBK24529.2 - 0.066 13.3 0.4 0.37 11.0 0.0 2.6 3 0 0 3 3 2 0 Tetratricopeptide repeat E1_UFD PF09358.10 CBK24529.2 - 0.11 13.2 1.0 0.3 11.8 1.0 1.7 1 0 0 1 1 1 0 Ubiquitin fold domain EcoEI_R_C PF08463.10 CBK24529.2 - 0.15 12.2 2.0 0.22 11.6 0.1 2.2 3 0 0 3 3 3 0 EcoEI R protein C-terminal NRDE-2 PF08424.10 CBK24529.2 - 0.29 10.2 16.8 1.9 7.5 0.1 4.2 3 1 1 4 4 4 0 NRDE-2, necessary for RNA interference FapA PF03961.13 CBK24529.2 - 1.1 7.8 2.6 1.9 7.0 2.6 1.3 1 0 0 1 1 1 0 Flagellar Assembly Protein A MCM6_C PF18263.1 CBK24529.2 - 2.5 8.4 4.5 2.4 8.4 0.8 2.6 3 0 0 3 3 3 0 MCM6 C-terminal winged-helix domain TPR_16 PF13432.6 CBK24529.2 - 4 8.2 11.7 0.27 11.9 3.6 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat Mito_carr PF00153.27 CBK24530.2 - 8.3e-65 214.8 2.8 5.6e-22 77.5 0.2 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein Isochorismatase PF00857.20 CBK24530.2 - 6.4e-12 46.0 0.0 2e-09 37.9 0.0 2.3 2 0 0 2 2 2 2 Isochorismatase family Serine_protease PF18405.1 CBK24530.2 - 0.00059 19.1 0.0 0.097 11.8 0.0 3.1 3 0 0 3 3 3 2 Gammaproteobacterial serine protease Ribosomal_L13e PF01294.18 CBK24531.2 - 8e-36 123.6 0.1 2.3e-35 122.1 0.1 1.7 1 1 0 1 1 1 1 Ribosomal protein L13e ubiquitin PF00240.23 CBK24532.2 - 1.6e-34 117.5 0.5 3.4e-34 116.4 0.5 1.5 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_S27 PF01599.19 CBK24532.2 - 4.2e-25 87.7 2.4 1.1e-24 86.4 2.4 1.7 1 0 0 1 1 1 1 Ribosomal protein S27a Rad60-SLD PF11976.8 CBK24532.2 - 9.9e-16 57.3 0.6 9.9e-16 57.3 0.6 1.7 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 CBK24532.2 - 2e-05 25.0 0.7 8.7e-05 22.9 0.1 2.2 2 1 0 2 2 2 1 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 CBK24532.2 - 0.00027 21.0 1.0 0.0006 19.9 1.0 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 CBK24532.2 - 0.0013 19.2 0.8 0.0019 18.7 0.8 1.2 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain TBK1_ULD PF18396.1 CBK24532.2 - 0.0058 16.5 0.0 0.0087 16.0 0.0 1.3 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain Ubiquitin_5 PF18037.1 CBK24532.2 - 0.0086 16.4 2.2 0.013 15.8 0.0 2.0 1 1 1 2 2 2 1 Ubiquitin-like domain IBR PF01485.21 CBK24532.2 - 0.038 14.2 0.6 0.062 13.5 0.5 1.4 1 1 0 1 1 1 0 IBR domain, a half RING-finger domain Ubiquitin_4 PF18036.1 CBK24532.2 - 0.27 11.3 5.4 4.7 7.3 0.2 2.5 3 0 0 3 3 3 0 Ubiquitin-like domain zf-ribbon_3 PF13248.6 CBK24532.2 - 3.9 7.0 7.0 45 3.6 7.0 2.2 1 1 0 1 1 1 0 zinc-ribbon domain P34-Arc PF04045.14 CBK24533.2 - 3.1e-40 138.4 0.0 4e-40 138.0 0.0 1.1 1 0 0 1 1 1 1 Arp2/3 complex, 34 kD subunit p34-Arc WD40 PF00400.32 CBK24534.2 - 4.3e-15 55.8 13.7 9.4e-08 32.6 0.1 5.6 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBK24534.2 - 0.035 14.4 0.0 2.7 8.4 0.0 3.1 2 1 1 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 CBK24535.2 - 6.9e-10 39.4 4.4 0.00033 21.4 0.0 4.4 4 1 0 4 4 4 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBK24535.2 - 0.00091 19.5 0.0 0.011 16.0 0.0 2.4 1 1 1 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain DUF543 PF04418.12 CBK24535.2 - 0.027 14.5 0.6 0.064 13.3 0.3 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF543) Ge1_WD40 PF16529.5 CBK24535.2 - 0.13 11.2 0.0 0.18 10.7 0.0 1.3 1 0 0 1 1 1 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Lactamase_B_2 PF12706.7 CBK24536.2 - 1.2e-13 51.0 0.0 1.2e-05 25.0 0.0 2.4 2 0 0 2 2 2 2 Beta-lactamase superfamily domain Lactamase_B PF00753.27 CBK24536.2 - 1.1e-06 28.8 0.0 1.9e-06 28.0 0.0 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily PDEase_II PF02112.15 CBK24536.2 - 0.0057 15.8 0.1 0.084 12.0 0.0 2.0 2 0 0 2 2 2 1 cAMP phosphodiesterases class-II CM2 PF03021.14 CBK24536.2 - 0.12 12.1 0.0 0.24 11.2 0.0 1.4 1 0 0 1 1 1 0 Influenza C virus M2 protein TRM PF02005.16 CBK24537.2 - 1e-14 54.5 0.0 1.3e-14 54.2 0.0 1.1 1 0 0 1 1 1 1 N2,N2-dimethylguanosine tRNA methyltransferase TRM PF02005.16 CBK24538.2 - 6.8e-75 252.6 0.2 8.1e-75 252.3 0.2 1.0 1 0 0 1 1 1 1 N2,N2-dimethylguanosine tRNA methyltransferase tRNA_U5-meth_tr PF05958.11 CBK24538.2 - 0.0019 17.3 0.0 0.0027 16.8 0.0 1.1 1 0 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase Met_10 PF02475.16 CBK24538.2 - 0.057 13.2 0.0 0.1 12.3 0.0 1.4 1 0 0 1 1 1 0 Met-10+ like-protein DHR10 PF18595.1 CBK24540.2 - 0.00054 20.0 29.3 0.0036 17.4 6.4 3.3 3 0 0 3 3 3 2 Designed helical repeat protein 10 domain NPV_P10 PF05531.12 CBK24540.2 - 0.0016 18.9 1.9 1.4 9.4 0.0 3.8 3 1 1 4 4 4 1 Nucleopolyhedrovirus P10 protein SlyX PF04102.12 CBK24540.2 - 0.0024 18.5 20.7 1.4 9.5 6.3 4.5 2 2 2 4 4 4 1 SlyX CENP-H PF05837.12 CBK24540.2 - 0.0025 18.2 1.5 0.0025 18.2 1.5 3.3 2 1 1 3 3 3 1 Centromere protein H (CENP-H) TPR_MLP1_2 PF07926.12 CBK24540.2 - 0.0031 17.6 14.2 0.0031 17.6 14.2 3.0 1 1 1 2 2 2 1 TPR/MLP1/MLP2-like protein SOGA PF11365.8 CBK24540.2 - 0.0041 18.2 4.4 0.0041 18.2 4.4 3.4 2 1 1 3 3 2 1 Protein SOGA DUF724 PF05266.14 CBK24540.2 - 0.0045 16.8 4.3 0.0045 16.8 4.3 3.1 1 1 2 3 3 3 1 Protein of unknown function (DUF724) ABC_tran_CTD PF16326.5 CBK24540.2 - 0.0059 16.8 0.5 0.0059 16.8 0.5 4.6 2 1 2 4 4 4 3 ABC transporter C-terminal domain HMMR_N PF15905.5 CBK24540.2 - 0.011 15.2 12.7 0.011 15.2 12.7 2.2 1 1 1 2 2 2 0 Hyaluronan mediated motility receptor N-terminal BLOC1_2 PF10046.9 CBK24540.2 - 0.013 15.8 20.7 0.16 12.3 5.9 4.2 2 2 1 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Vps51 PF08700.11 CBK24540.2 - 0.013 15.6 0.4 0.013 15.6 0.4 4.2 4 1 1 5 5 4 0 Vps51/Vps67 CCDC-167 PF15188.6 CBK24540.2 - 0.015 15.6 8.6 0.015 15.6 8.6 3.9 2 1 1 3 3 3 0 Coiled-coil domain-containing protein 167 Cytochrom_B562 PF07361.11 CBK24540.2 - 0.017 15.7 3.4 0.017 15.7 3.4 3.0 1 1 2 3 3 3 0 Cytochrome b562 bZIP_1 PF00170.21 CBK24540.2 - 0.026 14.6 27.1 0.37 10.9 3.0 5.2 3 1 2 5 5 5 0 bZIP transcription factor FUSC PF04632.12 CBK24540.2 - 0.031 12.8 3.4 0.042 12.4 3.4 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family Cep57_CLD_2 PF14197.6 CBK24540.2 - 0.032 14.3 2.9 0.032 14.3 2.9 4.2 3 1 1 4 4 3 0 Centrosome localisation domain of PPC89 DUF4988 PF16378.5 CBK24540.2 - 0.057 13.1 5.6 5.4 6.6 0.0 4.0 4 1 0 4 4 4 0 Domain of unknown function PilJ PF13675.6 CBK24540.2 - 0.082 12.9 4.1 0.78 9.8 0.0 3.0 1 1 1 3 3 3 0 Type IV pili methyl-accepting chemotaxis transducer N-term Fib_alpha PF08702.10 CBK24540.2 - 0.1 12.8 18.0 0.049 13.8 3.9 3.1 1 1 3 4 4 4 0 Fibrinogen alpha/beta chain family DUF3450 PF11932.8 CBK24540.2 - 0.12 11.7 27.4 0.086 12.1 8.2 3.4 1 1 2 3 3 3 0 Protein of unknown function (DUF3450) DUF2353 PF09789.9 CBK24540.2 - 0.12 11.7 26.2 0.014 14.8 16.0 2.1 1 1 1 2 2 2 0 Uncharacterized coiled-coil protein (DUF2353) DUF1664 PF07889.12 CBK24540.2 - 0.14 12.2 15.3 0.81 9.7 0.2 3.3 2 2 1 3 3 3 0 Protein of unknown function (DUF1664) ATG16 PF08614.11 CBK24540.2 - 0.19 12.0 27.9 13 5.9 4.3 3.3 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) CLZ PF16526.5 CBK24540.2 - 0.21 12.0 25.3 2.7 8.4 3.8 3.9 2 2 1 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DASH_Dam1 PF08653.10 CBK24540.2 - 0.28 11.0 7.3 24 4.8 0.1 4.8 5 0 0 5 5 5 0 DASH complex subunit Dam1 CENP-F_leu_zip PF10473.9 CBK24540.2 - 0.29 11.1 32.2 24 5.0 9.8 3.9 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Atg14 PF10186.9 CBK24540.2 - 0.31 10.1 16.9 1.4 8.0 16.9 1.8 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 HAP1_N PF04849.13 CBK24540.2 - 0.32 10.1 28.6 1.8 7.7 18.5 2.8 1 1 1 2 2 2 0 HAP1 N-terminal conserved region DUF2935 PF11155.8 CBK24540.2 - 0.33 11.3 13.8 5.8 7.3 6.1 3.1 1 1 1 2 2 2 0 Domain of unknown function (DUF2935) Lebercilin PF15619.6 CBK24540.2 - 0.37 10.4 29.7 0.66 9.6 7.7 3.6 1 1 2 3 3 3 0 Ciliary protein causing Leber congenital amaurosis disease Spc7 PF08317.11 CBK24540.2 - 0.38 9.6 29.5 0.035 13.0 16.2 2.3 1 1 1 2 2 2 0 Spc7 kinetochore protein FapA PF03961.13 CBK24540.2 - 0.39 9.3 24.7 0.033 12.8 7.8 2.3 1 1 1 2 2 2 0 Flagellar Assembly Protein A Baculo_PEP_C PF04513.12 CBK24540.2 - 0.48 10.5 3.8 9.9 6.2 0.2 2.5 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Cob_adeno_trans PF01923.18 CBK24540.2 - 0.54 10.4 11.9 0.57 10.3 0.3 3.1 1 1 2 3 3 3 0 Cobalamin adenosyltransferase DUF2721 PF11026.8 CBK24540.2 - 0.6 10.0 8.5 2 8.3 0.2 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF2721) DivIC PF04977.15 CBK24540.2 - 0.63 9.9 30.1 0.69 9.7 4.7 4.4 3 1 1 4 4 4 0 Septum formation initiator LPP PF04728.13 CBK24540.2 - 0.75 10.2 8.5 1.2 9.6 0.1 4.1 4 1 1 5 5 3 0 Lipoprotein leucine-zipper DUF948 PF06103.11 CBK24540.2 - 1 9.7 3.7 10 6.4 0.1 3.3 2 2 2 4 4 4 0 Bacterial protein of unknown function (DUF948) YabA PF06156.13 CBK24540.2 - 1.1 10.0 22.1 10 6.8 1.7 4.1 1 1 2 3 3 3 0 Initiation control protein YabA FlaC_arch PF05377.11 CBK24540.2 - 1.4 9.4 18.5 18 5.8 0.4 4.9 3 1 2 5 5 5 0 Flagella accessory protein C (FlaC) ADIP PF11559.8 CBK24540.2 - 1.7 8.7 27.1 2.9 8.0 10.7 3.6 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding Fmp27_WPPW PF10359.9 CBK24540.2 - 1.8 7.4 21.9 0.33 9.7 6.9 2.6 1 1 1 2 2 2 0 RNA pol II promoter Fmp27 protein domain TMF_DNA_bd PF12329.8 CBK24540.2 - 1.8 8.6 27.6 0.23 11.5 6.4 4.1 3 1 1 4 4 4 0 TATA element modulatory factor 1 DNA binding CALCOCO1 PF07888.11 CBK24540.2 - 1.8 7.3 28.9 1.5 7.6 6.9 2.5 1 1 0 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like DUF4140 PF13600.6 CBK24540.2 - 1.9 9.0 22.3 10 6.6 3.2 4.8 2 2 1 3 3 3 0 N-terminal domain of unknown function (DUF4140) TMF_TATA_bd PF12325.8 CBK24540.2 - 2.1 8.6 29.4 0.64 10.3 6.8 3.8 2 2 1 3 3 3 0 TATA element modulatory factor 1 TATA binding PRKG1_interact PF15898.5 CBK24540.2 - 2.3 9.2 29.7 32 5.5 8.6 3.2 1 1 1 2 2 2 0 cGMP-dependent protein kinase interacting domain GAS PF13851.6 CBK24540.2 - 2.4 7.5 29.6 0.98 8.7 12.1 2.6 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding DUF4200 PF13863.6 CBK24540.2 - 2.7 8.4 35.7 0.48 10.8 16.1 3.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) V_ATPase_I PF01496.19 CBK24540.2 - 2.9 5.7 17.3 0.15 9.9 6.7 2.3 1 1 2 3 3 3 0 V-type ATPase 116kDa subunit family DUF2730 PF10805.8 CBK24540.2 - 3.1 7.9 10.6 0.57 10.3 0.3 3.3 2 1 1 3 3 3 0 Protein of unknown function (DUF2730) PspA_IM30 PF04012.12 CBK24540.2 - 3.5 7.1 25.0 0.12 11.9 1.5 3.5 2 2 1 3 3 3 0 PspA/IM30 family Fez1 PF06818.15 CBK24540.2 - 3.7 8.0 26.9 30 5.0 22.1 2.7 1 1 1 2 2 2 0 Fez1 Seryl_tRNA_N PF02403.22 CBK24540.2 - 3.7 7.8 24.7 3.7 7.8 6.6 3.4 1 1 2 3 3 3 0 Seryl-tRNA synthetase N-terminal domain WDCP PF15390.6 CBK24540.2 - 4 5.7 11.8 0.32 9.3 6.1 1.7 1 1 1 2 2 2 0 WD repeat and coiled-coil-containing protein family FlxA PF14282.6 CBK24540.2 - 4.1 7.5 24.1 0.054 13.5 8.4 3.3 2 1 0 2 2 2 0 FlxA-like protein DUF3287 PF11690.8 CBK24540.2 - 4.2 7.1 8.0 8.7 6.1 0.1 3.2 1 1 1 3 3 3 0 Protein of unknown function (DUF3287) DUF4763 PF15960.5 CBK24540.2 - 4.2 6.6 25.6 0.54 9.5 10.2 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4763) TMPIT PF07851.13 CBK24540.2 - 4.2 6.5 21.0 0.17 11.1 7.2 2.9 1 1 2 3 3 3 0 TMPIT-like protein COG2 PF06148.11 CBK24540.2 - 5.3 7.1 15.5 12 6.0 5.2 3.1 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 PCRF PF03462.18 CBK24540.2 - 5.7 6.7 23.4 0.55 10.1 4.6 2.8 1 1 2 3 3 3 0 PCRF domain Suppressor_APC PF11414.8 CBK24540.2 - 6.2 7.0 17.2 8.9 6.5 2.4 3.4 2 2 0 2 2 2 0 Adenomatous polyposis coli tumour suppressor protein Cauli_AT PF03233.13 CBK24540.2 - 6.3 6.7 13.2 4.9 7.1 1.8 2.7 1 1 2 3 3 3 0 Aphid transmission protein HemX PF04375.14 CBK24540.2 - 6.3 6.0 20.9 3.2 6.9 7.1 2.7 1 1 2 3 3 3 0 HemX, putative uroporphyrinogen-III C-methyltransferase KfrA_N PF11740.8 CBK24540.2 - 6.5 7.5 17.9 0.9 10.2 2.0 3.6 2 1 1 3 3 2 0 Plasmid replication region DNA-binding N-term CorA PF01544.18 CBK24540.2 - 6.9 5.9 12.1 44 3.3 12.1 2.2 1 1 0 1 1 1 0 CorA-like Mg2+ transporter protein Prefoldin_2 PF01920.20 CBK24540.2 - 7.3 6.6 30.8 0.75 9.8 10.7 4.5 1 1 1 3 3 2 0 Prefoldin subunit Laminin_II PF06009.12 CBK24540.2 - 7.5 6.6 13.4 1.1 9.3 2.4 3.2 2 2 1 3 3 3 0 Laminin Domain II Exonuc_VII_L PF02601.15 CBK24540.2 - 7.8 6.0 18.7 79 2.7 18.7 2.0 1 1 0 1 1 1 0 Exonuclease VII, large subunit H-kinase_dim PF02895.14 CBK24540.2 - 8.7 6.8 12.6 18 5.8 0.4 3.3 3 0 0 3 3 3 0 Signal transducing histidine kinase, homodimeric domain Myb_DNA-binding PF00249.31 CBK24541.2 - 2.4e-05 24.4 1.4 2.4e-05 24.4 1.4 2.1 2 1 0 2 2 2 1 Myb-like DNA-binding domain SLIDE PF09111.10 CBK24541.2 - 0.00016 21.6 0.7 0.00024 21.1 0.7 1.4 1 0 0 1 1 1 1 SLIDE Myb_DNA-bind_6 PF13921.6 CBK24541.2 - 0.036 14.3 0.4 0.036 14.3 0.4 1.8 2 0 0 2 2 2 0 Myb-like DNA-binding domain HAT_KAT11 PF08214.11 CBK24542.2 - 2.1e-17 63.5 1.2 4.3e-17 62.4 1.2 1.4 1 1 0 1 1 1 1 Histone acetylation protein HSP70 PF00012.20 CBK24543.2 - 1e-216 720.8 4.4 1.2e-216 720.5 4.4 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 CBK24543.2 - 6.4e-12 44.9 0.0 1.6e-11 43.6 0.0 1.6 1 0 0 1 1 1 1 MreB/Mbl protein DDR PF08841.10 CBK24543.2 - 0.0039 16.2 0.7 0.29 10.1 0.0 2.8 3 0 0 3 3 3 2 Diol dehydratase reactivase ATPase-like domain FERM_f0 PF16511.5 CBK24543.2 - 0.068 13.5 1.5 1.7 9.0 0.3 2.5 2 0 0 2 2 2 0 N-terminal or F0 domain of Talin-head FERM Phage_Cox PF10743.9 CBK24543.2 - 0.15 12.2 0.1 0.35 11.0 0.1 1.6 1 0 0 1 1 1 0 Regulatory phage protein cox His_Phos_2 PF00328.22 CBK24544.2 - 4.8e-10 39.3 0.0 3.4e-05 23.4 0.0 2.2 1 1 0 2 2 2 2 Histidine phosphatase superfamily (branch 2) zf-RING_UBOX PF13445.6 CBK24544.2 - 0.069 13.2 0.1 0.28 11.2 0.0 2.0 2 0 0 2 2 2 0 RING-type zinc-finger TA_inhibitor PF17574.2 CBK24545.2 - 7.9e-06 25.8 0.0 0.016 15.2 0.0 3.0 3 0 0 3 3 3 2 Inhibitor of toxin/antitoxin system (Gp4.5) HpcH_HpaI PF03328.14 CBK24545.2 - 0.21 10.7 0.0 0.37 9.9 0.0 1.3 1 0 0 1 1 1 0 HpcH/HpaI aldolase/citrate lyase family DUF2158 PF09926.9 CBK24545.2 - 2.4 8.0 5.9 25 4.7 0.1 3.8 4 0 0 4 4 4 0 Uncharacterized small protein (DUF2158) YjeF_N PF03853.15 CBK24546.2 - 6.3e-34 117.3 0.0 9.6e-34 116.7 0.0 1.3 1 1 0 1 1 1 1 YjeF-related protein N-terminus TMEM43 PF07787.12 CBK24548.2 - 4.7e-07 29.4 0.1 4.7e-07 29.4 0.1 2.3 2 0 0 2 2 2 1 Transmembrane protein 43 PRKCSH-like PF12999.7 CBK24549.2 - 5.1e-37 127.4 7.2 5.5e-37 127.2 7.2 1.1 1 0 0 1 1 1 1 Glucosidase II beta subunit-like Ldl_recept_a PF00057.18 CBK24549.2 - 0.0011 19.1 20.1 0.0034 17.6 1.1 2.8 3 1 0 3 3 3 2 Low-density lipoprotein receptor domain class A PRKCSH_1 PF13015.6 CBK24550.2 - 1.3e-18 67.2 0.8 2.4e-18 66.3 0.8 1.4 1 1 0 1 1 1 1 Glucosidase II beta subunit-like protein PRKCSH PF07915.13 CBK24550.2 - 0.029 15.3 3.2 0.029 15.3 3.2 1.9 2 0 0 2 2 2 0 Glucosidase II beta subunit-like protein HEAT_2 PF13646.6 CBK24551.2 - 0.002 18.5 0.3 28 5.2 0.1 3.8 3 0 0 3 3 3 3 HEAT repeats Ribosomal_L38e PF01781.18 CBK24552.2 - 8.4e-27 93.1 0.6 1.9e-26 92.0 0.6 1.6 1 0 0 1 1 1 1 Ribosomal L38e protein family BRK PF07533.16 CBK24552.2 - 2.6e-05 23.8 0.0 4.9e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 BRK domain Laminin_II PF06009.12 CBK24552.2 - 0.1 12.6 0.1 0.2 11.7 0.1 1.4 1 0 0 1 1 1 0 Laminin Domain II PHINT_rpt PF14882.6 CBK24552.2 - 0.14 12.5 0.7 0.29 11.4 0.1 1.9 2 0 0 2 2 2 0 Phage-integrase repeat unit HOOK PF05622.12 CBK24553.2 - 0.0012 17.1 14.3 0.002 16.4 14.3 1.2 1 0 0 1 1 1 1 HOOK protein CENP-H PF05837.12 CBK24553.2 - 0.0019 18.6 14.7 0.039 14.3 4.8 2.4 1 1 1 2 2 2 2 Centromere protein H (CENP-H) ATG16 PF08614.11 CBK24553.2 - 0.007 16.6 13.4 0.011 16.0 13.4 1.3 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) HALZ PF02183.18 CBK24553.2 - 0.0073 16.5 11.8 6.2 7.1 1.0 4.3 3 0 0 3 3 3 1 Homeobox associated leucine zipper KASH_CCD PF14662.6 CBK24553.2 - 0.0095 15.8 16.9 0.024 14.5 16.8 1.6 1 1 0 1 1 1 1 Coiled-coil region of CCDC155 or KASH Spc42p PF11544.8 CBK24553.2 - 0.01 15.8 1.6 0.01 15.8 1.6 2.2 2 1 0 2 2 2 0 Spindle pole body component Spc42p SlyX PF04102.12 CBK24553.2 - 0.019 15.6 0.3 0.019 15.6 0.3 2.8 2 1 0 2 2 2 0 SlyX DUF5082 PF16888.5 CBK24553.2 - 0.067 13.5 8.8 0.18 12.1 0.6 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF5082) Spc7 PF08317.11 CBK24553.2 - 0.091 11.6 11.5 0.15 11.0 11.5 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein Uso1_p115_C PF04871.13 CBK24553.2 - 0.1 13.0 9.2 0.21 12.0 9.2 1.6 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region DivIC PF04977.15 CBK24553.2 - 0.12 12.1 10.5 2.6 7.9 0.2 3.4 2 1 1 3 3 3 0 Septum formation initiator bZIP_2 PF07716.15 CBK24553.2 - 0.22 11.6 14.7 3.3 7.9 0.2 4.6 3 1 1 4 4 4 0 Basic region leucine zipper FPP PF05911.11 CBK24553.2 - 0.34 9.1 14.8 0.46 8.6 14.8 1.1 1 0 0 1 1 1 0 Filament-like plant protein, long coiled-coil DUF812 PF05667.11 CBK24553.2 - 0.45 9.4 11.4 0.65 8.8 11.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) ADIP PF11559.8 CBK24553.2 - 0.68 10.0 17.2 1.9 8.5 9.2 2.3 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding TPR_MLP1_2 PF07926.12 CBK24553.2 - 0.73 9.9 18.8 0.32 11.1 7.7 3.0 2 1 1 3 3 3 0 TPR/MLP1/MLP2-like protein GAS PF13851.6 CBK24553.2 - 1.1 8.6 14.9 0.42 9.9 3.6 2.3 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding FlxA PF14282.6 CBK24553.2 - 1.3 9.1 13.7 3.4 7.7 8.6 2.4 1 1 1 2 2 2 0 FlxA-like protein DivIVA PF05103.13 CBK24553.2 - 1.7 8.8 8.5 0.69 10.0 5.2 1.9 1 1 1 2 2 2 0 DivIVA protein DUF4763 PF15960.5 CBK24553.2 - 1.9 7.7 17.2 2.8 7.2 3.0 2.9 1 1 2 3 3 3 0 Domain of unknown function (DUF4763) DUF3496 PF12001.8 CBK24553.2 - 2.6 8.5 10.2 2.9 8.3 1.2 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3496) Mod_r PF07200.13 CBK24553.2 - 3.4 7.7 15.3 12 6.0 4.7 2.2 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein DUF4200 PF13863.6 CBK24553.2 - 4.8 7.6 8.8 4.4 7.7 6.4 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) Cnn_1N PF07989.11 CBK24553.2 - 4.9 7.4 11.9 19 5.5 6.6 2.7 1 1 1 2 2 2 0 Centrosomin N-terminal motif 1 BRE1 PF08647.11 CBK24553.2 - 5.1 7.2 13.3 0.42 10.7 3.9 2.8 1 1 0 2 2 2 0 BRE1 E3 ubiquitin ligase PRKG1_interact PF15898.5 CBK24553.2 - 5.2 8.0 17.8 8.5 7.3 9.2 3.0 1 1 2 3 3 3 0 cGMP-dependent protein kinase interacting domain APG6_N PF17675.1 CBK24553.2 - 9.5 6.8 15.7 7.1e+02 0.7 15.7 2.5 1 1 0 1 1 1 0 Apg6 coiled-coil region Pkinase PF00069.25 CBK24554.2 - 7.2e-05 22.3 0.0 7.9e-05 22.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Ins_beta PF03488.14 CBK24555.2 - 0.00078 19.4 1.7 0.14 12.1 0.0 3.4 3 0 0 3 3 3 2 Nematode insulin-related peptide beta type G-patch_2 PF12656.7 CBK24556.2 - 0.0034 17.4 0.7 0.0075 16.3 0.0 1.9 2 1 0 2 2 2 1 G-patch domain Ribosomal_L12 PF00542.19 CBK24557.2 - 1e-19 70.6 6.6 1e-19 70.6 6.6 3.4 2 1 0 3 3 3 2 Ribosomal protein L7/L12 C-terminal domain DUF2267 PF10025.9 CBK24557.2 - 0.2 11.9 3.2 0.22 11.8 0.0 2.4 3 1 0 3 3 3 0 Uncharacterized conserved protein (DUF2267) Ribosomal_60s PF00428.19 CBK24557.2 - 0.22 12.1 31.2 0.052 14.1 9.5 3.1 3 1 0 3 3 3 0 60s Acidic ribosomal protein PARM PF17061.5 CBK24557.2 - 0.31 11.2 2.6 0.5 10.5 2.6 1.2 1 0 0 1 1 1 0 PARM PcfK PF14058.6 CBK24557.2 - 0.8 10.0 8.7 0.11 12.8 1.0 2.3 2 0 0 2 2 2 0 PcfK-like protein CSN5_C PF18323.1 CBK24557.2 - 2.4 9.1 9.7 6 7.9 4.2 2.4 2 0 0 2 2 2 0 Cop9 signalosome subunit 5 C-terminal domain RRN3 PF05327.11 CBK24558.2 - 0.15 10.6 8.2 0.18 10.3 8.2 1.0 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Rtf2 PF04641.12 CBK24558.2 - 0.16 11.3 3.1 0.23 10.8 3.1 1.1 1 0 0 1 1 1 0 Rtf2 RING-finger DUF3484 PF11983.8 CBK24558.2 - 0.19 12.8 2.6 1.5 10.0 2.6 2.1 1 1 0 1 1 1 0 Membrane-attachment and polymerisation-promoting switch TP53IP5 PF15331.6 CBK24558.2 - 0.23 11.6 0.9 0.27 11.4 0.9 1.1 1 0 0 1 1 1 0 Cellular tumour antigen p53-inducible 5 DnaJ_C PF01556.18 CBK24559.2 - 6.4e-16 58.8 0.0 1.1e-15 58.1 0.0 1.4 1 1 0 1 1 1 1 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.19 CBK24559.2 - 0.00073 19.9 1.8 0.0015 18.9 1.8 1.4 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 CBK24559.2 - 0.066 13.2 4.6 0.072 13.1 3.1 1.8 2 0 0 2 2 2 0 Tryptophan RNA-binding attenuator protein inhibitory protein PhnH PF05845.12 CBK24559.2 - 0.13 12.0 0.0 0.21 11.3 0.0 1.3 1 0 0 1 1 1 0 Bacterial phosphonate metabolism protein (PhnH) A2L_zn_ribbon PF08792.10 CBK24559.2 - 0.2 11.4 0.0 0.2 11.4 0.0 2.0 2 0 0 2 2 2 0 A2L zinc ribbon domain Hypoth_Ymh PF09509.10 CBK24560.2 - 0.035 14.0 0.0 0.038 13.9 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (Hypoth_ymh) IP_trans PF02121.18 CBK24561.2 - 1.1e-78 264.2 0.7 1.7e-78 263.6 0.7 1.3 1 0 0 1 1 1 1 Phosphatidylinositol transfer protein Ssl1 PF04056.14 CBK24561.2 - 1.6e-41 142.2 0.7 2.7e-41 141.5 0.7 1.4 1 0 0 1 1 1 1 Ssl1-like VWA_2 PF13519.6 CBK24561.2 - 0.00032 21.3 0.0 0.0008 20.0 0.0 1.7 1 0 0 1 1 1 1 von Willebrand factor type A domain C1_4 PF07975.12 CBK24561.2 - 0.0016 18.6 20.0 0.0016 18.6 20.0 3.5 2 1 0 2 2 2 1 TFIIH C1-like domain Vps26 PF03643.15 CBK24562.2 - 8.9e-84 280.7 6.0 1e-83 280.5 6.0 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Arrestin_C PF02752.22 CBK24562.2 - 0.0012 19.3 0.5 0.0087 16.5 0.1 2.2 2 1 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Rgp1 PF08737.10 CBK24562.2 - 0.047 12.9 0.4 0.27 10.3 0.1 1.9 2 0 0 2 2 2 0 Rgp1 Arrestin_N PF00339.29 CBK24562.2 - 0.056 13.5 1.6 1.4 8.9 0.1 2.9 2 1 1 3 3 3 0 Arrestin (or S-antigen), N-terminal domain Tubulin PF00091.25 CBK24563.2 - 1.4e-65 221.2 0.0 4.9e-65 219.4 0.0 1.8 2 0 0 2 2 2 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 CBK24563.2 - 3.9e-37 127.2 0.0 1.1e-36 125.8 0.0 1.7 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 CBK24563.2 - 0.0041 17.4 0.0 0.0096 16.2 0.0 1.7 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_2 PF13809.6 CBK24563.2 - 0.043 13.0 0.0 0.065 12.4 0.0 1.3 1 0 0 1 1 1 0 Tubulin like EF-hand_3 PF09069.11 CBK24563.2 - 0.16 12.4 0.1 0.5 10.8 0.1 1.8 2 0 0 2 2 2 0 EF-hand Ribosomal_L20 PF00453.18 CBK24564.2 - 1.9e-36 124.4 7.6 2.2e-36 124.2 7.6 1.0 1 0 0 1 1 1 1 Ribosomal protein L20 PH_13 PF16652.5 CBK24564.2 - 0.098 12.5 0.6 0.29 10.9 0.1 1.7 1 1 1 2 2 2 0 Pleckstrin homology domain Ribosomal_L24e PF01246.20 CBK24566.2 - 5e-27 93.9 1.8 5e-27 93.9 1.8 1.8 2 0 0 2 2 2 1 Ribosomal protein L24e FragX_IP PF05994.11 CBK24568.2 - 4.4e-26 91.3 1.8 6.9e-26 90.6 1.8 1.2 1 0 0 1 1 1 1 Cytoplasmic Fragile-X interacting family HMw1_D2 PF18254.1 CBK24568.2 - 0.16 12.4 0.4 6.9 7.1 0.1 3.6 3 1 1 4 4 4 0 HMW1 domain 2 Pkinase PF00069.25 CBK24570.2 - 9.3e-68 228.4 0.0 1.2e-67 228.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBK24570.2 - 1.1e-30 106.8 0.0 1.5e-30 106.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase FYVE PF01363.21 CBK24570.2 - 1.2e-19 70.2 10.7 2.7e-19 69.1 10.7 1.5 1 0 0 1 1 1 1 FYVE zinc finger Kinase-like PF14531.6 CBK24570.2 - 0.0017 17.7 0.0 0.0057 16.0 0.0 1.8 2 0 0 2 2 2 1 Kinase-like FYVE_2 PF02318.16 CBK24570.2 - 0.002 18.4 7.6 0.0049 17.1 7.6 1.6 1 0 0 1 1 1 1 FYVE-type zinc finger Kdo PF06293.14 CBK24570.2 - 0.06 12.7 0.0 0.12 11.7 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family WD40 PF00400.32 CBK24571.2 - 2.8e-11 43.8 0.2 0.0046 17.8 0.0 5.3 5 0 0 5 5 5 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBK24571.2 - 6.6e-06 26.3 0.0 0.0034 17.7 0.1 3.4 3 1 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 CBK24571.2 - 0.013 14.2 0.1 0.075 11.7 0.1 2.0 2 0 0 2 2 2 0 Nucleoporin Nup120/160 COPIIcoated_ERV PF07970.12 CBK24572.2 - 3e-62 210.4 0.3 4.6e-62 209.7 0.3 1.3 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 CBK24572.2 - 6.4e-27 93.7 0.1 1.7e-26 92.3 0.1 1.8 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) POT1 PF02765.17 CBK24572.2 - 0.09 12.6 0.1 0.2 11.5 0.1 1.6 1 0 0 1 1 1 0 Telomeric single stranded DNA binding POT1/CDC13 FlaC_arch PF05377.11 CBK24573.2 - 0.75 10.2 8.6 2.6 8.5 0.0 4.1 3 2 1 4 4 4 0 Flagella accessory protein C (FlaC) FTCD_N PF07837.12 CBK24574.2 - 6.4e-71 237.8 0.0 9.6e-71 237.2 0.0 1.3 1 0 0 1 1 1 1 Formiminotransferase domain, N-terminal subdomain FTCD_C PF04961.12 CBK24574.2 - 1.1e-69 233.8 0.0 2.5e-69 232.7 0.0 1.6 1 0 0 1 1 1 1 Formiminotransferase-cyclodeaminase FTCD PF02971.14 CBK24574.2 - 3e-61 205.7 0.1 4.9e-61 205.0 0.1 1.4 1 0 0 1 1 1 1 Formiminotransferase domain Ribosomal_L28e PF01778.17 CBK24575.2 - 1.9e-06 28.6 1.8 1.9e-06 28.6 1.8 1.9 1 1 1 2 2 2 1 Ribosomal L28e protein family Pkinase PF00069.25 CBK24576.2 - 4.3e-24 85.3 0.0 5e-24 85.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBK24576.2 - 2.6e-18 66.3 0.0 2.9e-18 66.1 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CBK24576.2 - 3.8e-05 22.6 0.0 4.8e-05 22.3 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 CBK24576.2 - 0.0013 18.8 0.0 0.0014 18.6 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 CBK24576.2 - 0.0022 17.0 0.0 0.0027 16.7 0.0 1.1 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 CBK24576.2 - 0.012 15.0 0.0 0.016 14.6 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 CBK24576.2 - 0.02 14.2 0.0 0.024 13.9 0.0 1.1 1 0 0 1 1 1 0 Kinase-like Choline_kinase PF01633.20 CBK24576.2 - 0.022 14.3 0.0 0.029 14.0 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase Seadorna_VP7 PF07387.11 CBK24576.2 - 0.12 11.5 0.0 0.16 11.0 0.0 1.1 1 0 0 1 1 1 0 Seadornavirus VP7 DUF3446 PF11928.8 CBK24577.2 - 0.023 15.0 9.0 0.023 15.0 9.0 2.1 2 0 0 2 2 2 0 Early growth response N-terminal domain FAM104 PF15434.6 CBK24577.2 - 1.3 9.6 9.4 0.56 10.8 3.2 2.3 2 0 0 2 2 2 0 Family 104 AMPKBI PF04739.15 CBK24578.2 - 3.7e-20 72.0 1.0 6.9e-20 71.1 1.0 1.4 1 0 0 1 1 1 1 5'-AMP-activated protein kinase beta subunit, interaction domain AMPK1_CBM PF16561.5 CBK24578.2 - 1.7e-15 57.0 0.3 4.9e-15 55.5 0.3 1.7 1 1 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase SKICH PF17751.1 CBK24578.2 - 0.07 13.7 0.3 0.16 12.6 0.3 1.6 1 1 0 1 1 1 0 SKICH domain Nore1-SARAH PF16517.5 CBK24578.2 - 4.3 7.3 8.5 13 5.8 8.5 1.9 1 1 0 1 1 1 0 Novel Ras effector 1 C-terminal SARAH (Sav/Rassf/Hpo) domain RabGAP-TBC PF00566.18 CBK24579.2 - 1e-39 136.4 2.9 6.1e-39 133.9 2.9 1.9 1 1 0 1 1 1 1 Rab-GTPase-TBC domain ELL PF10390.9 CBK24579.2 - 0.23 10.9 0.1 0.37 10.3 0.1 1.2 1 0 0 1 1 1 0 RNA polymerase II elongation factor ELL AAA_33 PF13671.6 CBK24580.2 - 1.5e-17 64.1 0.1 7.8e-10 39.1 0.3 2.1 1 1 1 2 2 2 2 AAA domain KTI12 PF08433.10 CBK24580.2 - 1e-06 28.4 0.1 0.005 16.3 0.1 2.1 1 1 0 1 1 1 1 Chromatin associated protein KTI12 Zeta_toxin PF06414.12 CBK24580.2 - 4.8e-06 26.0 0.0 0.00043 19.6 0.0 2.1 1 1 1 2 2 2 1 Zeta toxin AAA_16 PF13191.6 CBK24580.2 - 4.2e-05 24.0 0.0 5.7e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 CBK24580.2 - 0.0005 20.3 0.0 0.0011 19.2 0.0 1.5 1 1 0 1 1 1 1 AAA domain TniB PF05621.11 CBK24580.2 - 0.0025 17.3 0.0 0.0039 16.6 0.0 1.5 1 1 0 1 1 1 1 Bacterial TniB protein 6PF2K PF01591.18 CBK24580.2 - 0.0048 16.2 0.0 0.61 9.3 0.0 2.5 1 1 2 3 3 3 1 6-phosphofructo-2-kinase ABC_tran PF00005.27 CBK24580.2 - 0.0095 16.5 0.0 0.012 16.2 0.0 1.2 1 0 0 1 1 1 1 ABC transporter Ploopntkinase3 PF18751.1 CBK24580.2 - 0.015 15.2 0.0 0.022 14.6 0.0 1.3 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 AAA_29 PF13555.6 CBK24580.2 - 0.035 13.8 0.0 0.063 13.0 0.0 1.3 1 0 0 1 1 1 0 P-loop containing region of AAA domain PNK3P PF08645.11 CBK24580.2 - 0.036 13.8 0.0 0.086 12.5 0.0 1.6 1 0 0 1 1 1 0 Polynucleotide kinase 3 phosphatase MMR_HSR1 PF01926.23 CBK24580.2 - 0.042 13.9 0.0 0.061 13.4 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase RNA_helicase PF00910.22 CBK24580.2 - 0.044 14.2 0.0 0.071 13.5 0.0 1.4 1 0 0 1 1 1 0 RNA helicase AAA_25 PF13481.6 CBK24580.2 - 0.062 12.9 0.0 0.11 12.1 0.0 1.4 1 1 0 1 1 1 0 AAA domain AAA_7 PF12775.7 CBK24580.2 - 0.079 12.5 0.0 0.11 12.0 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region NB-ARC PF00931.22 CBK24580.2 - 0.11 11.6 0.0 0.15 11.2 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain AAA_18 PF13238.6 CBK24580.2 - 0.14 12.7 0.0 0.29 11.7 0.0 1.6 1 1 0 1 1 1 0 AAA domain Roc PF08477.13 CBK24580.2 - 0.17 12.1 0.0 0.61 10.3 0.0 1.9 1 1 1 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase LSM PF01423.22 CBK24581.2 - 2e-07 30.6 0.5 7.3e-05 22.4 0.0 2.2 2 0 0 2 2 2 2 LSM domain CactinC_cactus PF09732.9 CBK24582.2 - 3.5e-54 182.1 9.5 5.3e-54 181.5 9.5 1.3 1 0 0 1 1 1 1 Cactus-binding C-terminus of cactin protein Cactin_mid PF10312.9 CBK24582.2 - 2.6e-28 99.1 0.7 3.8e-28 98.6 0.2 1.5 1 1 0 1 1 1 1 Conserved mid region of cactin DUF3299 PF11736.8 CBK24582.2 - 0.12 12.4 0.6 19 5.3 0.6 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3299) Draxin PF15550.6 CBK24582.2 - 0.26 11.1 10.0 0.54 10.1 10.0 1.6 1 0 0 1 1 1 0 Draxin BOP1NT PF08145.12 CBK24584.2 - 4.5e-49 167.7 6.4 1.3e-48 166.2 6.4 1.7 1 1 0 1 1 1 1 BOP1NT (NUC169) domain WD40 PF00400.32 CBK24584.2 - 9.3e-13 48.4 4.8 0.00013 22.7 0.0 4.6 4 0 0 4 4 4 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBK24584.2 - 0.036 14.3 0.0 7.2 7.0 0.1 3.2 1 1 2 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain TCP PF03634.13 CBK24584.2 - 0.11 13.1 0.5 0.22 12.1 0.5 1.5 1 0 0 1 1 1 0 TCP family transcription factor V-ATPase_C PF03223.15 CBK24585.2 - 4.6e-83 279.7 0.8 5.5e-83 279.4 0.8 1.0 1 0 0 1 1 1 1 V-ATPase subunit C DGF-1_C PF11040.8 CBK24585.2 - 0.13 12.3 0.2 0.25 11.3 0.2 1.5 1 0 0 1 1 1 0 Dispersed gene family protein 1 of Trypanosoma cruzi C-terminus SH3_9 PF14604.6 CBK24586.2 - 1.8e-15 56.5 0.1 3.9e-15 55.4 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 CBK24586.2 - 1e-14 53.9 0.0 1.9e-14 53.0 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 CBK24586.2 - 7.1e-11 41.6 0.0 1.4e-10 40.7 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain Arfaptin PF06456.13 CBK24586.2 - 0.00023 20.8 10.0 0.00034 20.3 10.0 1.2 1 0 0 1 1 1 1 Arfaptin-like domain Occludin_ELL PF07303.13 CBK24586.2 - 0.092 13.5 0.5 0.092 13.5 0.5 3.0 1 1 2 3 3 3 0 Occludin homology domain IFT20 PF14931.6 CBK24586.2 - 0.099 12.8 0.1 0.099 12.8 0.1 2.3 2 1 1 3 3 3 0 Intraflagellar transport complex B, subunit 20 Ribosomal_L14e PF01929.17 CBK24587.2 - 3.5e-28 97.9 4.2 4.5e-28 97.6 4.2 1.1 1 0 0 1 1 1 1 Ribosomal protein L14 KOW PF00467.29 CBK24587.2 - 0.016 15.2 0.0 0.025 14.5 0.0 1.3 1 0 0 1 1 1 0 KOW motif SWIRM-assoc_3 PF16498.5 CBK24587.2 - 0.1 12.9 1.5 0.23 11.7 1.5 1.5 1 0 0 1 1 1 0 SWIRM-associated domain at the C-terminal PUF PF00806.19 CBK24588.2 - 5.8e-47 154.8 7.8 1.3e-08 34.0 0.0 8.3 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat CPL PF08144.11 CBK24588.2 - 2.3e-05 24.8 0.2 0.6 10.5 0.0 3.9 1 1 2 3 3 3 3 CPL (NUC119) domain DUF1397 PF07165.11 CBK24588.2 - 0.0086 15.5 4.6 0.011 15.2 1.3 2.4 1 1 0 2 2 2 1 Protein of unknown function (DUF1397) Complex1_LYR PF05347.15 CBK24589.2 - 9.1e-10 38.4 0.7 1.3e-09 38.0 0.7 1.2 1 0 0 1 1 1 1 Complex 1 protein (LYR family) LPD5 PF18799.1 CBK24589.2 - 0.0041 17.5 0.1 0.005 17.3 0.1 1.1 1 0 0 1 1 1 1 Large polyvalent protein-associated domain 5 Complex1_LYR_2 PF13233.6 CBK24589.2 - 0.0044 17.7 1.3 0.0051 17.5 1.3 1.4 1 1 0 1 1 1 1 Complex1_LYR-like Complex1_LYR_1 PF13232.6 CBK24589.2 - 0.07 13.7 1.7 0.078 13.6 0.2 1.9 2 0 0 2 2 2 0 Complex1_LYR-like WSK PF03832.13 CBK24589.2 - 0.13 12.0 0.1 0.22 11.2 0.1 1.4 1 0 0 1 1 1 0 WSK motif Clathrin PF00637.20 CBK24590.2 - 5.3e-174 571.0 36.6 4.8e-32 110.8 0.0 8.1 8 0 0 8 8 8 7 Region in Clathrin and VPS Clathrin_H_link PF13838.6 CBK24590.2 - 1.5e-23 82.4 3.2 4.2e-23 81.0 0.2 3.3 2 1 1 3 3 3 1 Clathrin-H-link Clathrin_propel PF01394.20 CBK24590.2 - 3.5e-10 39.7 0.1 3.1e-05 24.0 0.0 5.3 5 0 0 5 5 5 1 Clathrin propeller repeat Coatomer_WDAD PF04053.14 CBK24590.2 - 0.026 13.6 0.0 0.026 13.6 0.0 4.2 5 0 0 5 5 5 0 Coatomer WD associated region DUF543 PF04418.12 CBK24590.2 - 0.081 12.9 0.0 0.23 11.5 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF543) TPR_12 PF13424.6 CBK24590.2 - 0.13 12.6 1.4 23 5.4 0.1 4.6 3 0 0 3 3 3 0 Tetratricopeptide repeat PCP PF02429.15 CBK24590.2 - 0.21 11.9 2.2 2.1 8.7 0.3 3.3 3 0 0 3 3 3 0 Peridinin-chlorophyll A binding protein TPR_7 PF13176.6 CBK24590.2 - 1.5 9.0 14.7 32 4.9 0.1 7.6 9 0 0 9 9 9 0 Tetratricopeptide repeat ANAPC3 PF12895.7 CBK24590.2 - 5.8 7.2 12.6 6.2 7.1 2.0 4.9 4 1 1 5 5 5 0 Anaphase-promoting complex, cyclosome, subunit 3 Thioredoxin PF00085.20 CBK24591.2 - 2.1e-22 79.0 0.0 3.7e-22 78.3 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 CBK24591.2 - 8.4e-07 29.4 0.1 2e-06 28.2 0.1 1.6 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 CBK24591.2 - 2.3e-05 24.6 0.1 0.00025 21.3 0.1 2.2 1 1 1 2 2 2 2 Thioredoxin-like Thioredoxin_7 PF13899.6 CBK24591.2 - 0.0014 18.7 0.0 0.0031 17.7 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin-like Redoxin PF08534.10 CBK24591.2 - 0.0059 16.3 0.0 0.016 14.9 0.0 1.6 1 1 1 2 2 2 1 Redoxin DUF2001 PF09393.10 CBK24591.2 - 0.045 13.8 0.4 0.074 13.0 0.4 1.3 1 0 0 1 1 1 0 Phage tail tube protein Myc_N PF01056.18 CBK24591.2 - 0.046 13.6 0.1 0.067 13.1 0.1 1.3 1 0 0 1 1 1 0 Myc amino-terminal region Thioredoxin_9 PF14595.6 CBK24591.2 - 0.18 11.6 0.0 0.33 10.7 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin tRNA-synt_1b PF00579.25 CBK24592.2 - 9e-18 64.6 0.2 5.3e-17 62.1 0.0 2.3 2 2 1 3 3 3 1 tRNA synthetases class I (W and Y) DUF4287 PF14117.6 CBK24592.2 - 0.057 13.6 0.0 0.13 12.4 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4287) AAA PF00004.29 CBK24593.2 - 1.9e-36 125.4 0.0 2.9e-36 124.8 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CBK24593.2 - 5e-11 42.2 0.0 1.2e-10 41.0 0.0 1.7 1 0 0 1 1 1 1 AAA+ lid domain Vps4_C PF09336.10 CBK24593.2 - 2.4e-06 27.4 0.0 5.5e-06 26.3 0.0 1.6 1 0 0 1 1 1 1 Vps4 C terminal oligomerisation domain AAA_5 PF07728.14 CBK24593.2 - 2.4e-05 24.3 0.5 0.00027 21.0 0.5 2.5 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 CBK24593.2 - 5.9e-05 22.9 0.1 0.0002 21.1 0.0 1.9 2 1 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 CBK24593.2 - 0.00045 20.5 1.6 0.089 13.1 0.2 2.7 1 1 2 3 3 3 1 AAA domain TIP49 PF06068.13 CBK24593.2 - 0.0034 16.6 0.1 0.0084 15.4 0.1 1.5 1 1 0 1 1 1 1 TIP49 P-loop domain AAA_16 PF13191.6 CBK24593.2 - 0.022 15.1 1.0 0.23 11.8 0.2 2.4 2 1 0 2 2 2 0 AAA ATPase domain Sigma54_activat PF00158.26 CBK24593.2 - 0.024 14.4 0.1 4.8 6.9 0.0 2.3 2 0 0 2 2 2 0 Sigma-54 interaction domain IstB_IS21 PF01695.17 CBK24593.2 - 0.034 13.9 0.1 0.062 13.0 0.1 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein Mg_chelatase PF01078.21 CBK24593.2 - 0.061 12.7 0.2 0.12 11.7 0.2 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_2 PF07724.14 CBK24593.2 - 0.089 12.9 0.0 0.18 11.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) AAA_18 PF13238.6 CBK24593.2 - 0.11 13.0 0.0 0.22 12.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 CBK24593.2 - 0.15 11.6 0.6 2.9 7.4 0.2 2.3 1 1 0 2 2 2 0 AAA domain AAA_24 PF13479.6 CBK24593.2 - 0.31 10.7 1.1 0.83 9.3 0.2 2.3 2 1 0 2 2 2 0 AAA domain Ribosomal_S2 PF00318.20 CBK24594.2 - 1.2e-30 106.4 2.8 2.1e-15 56.6 0.2 2.2 1 1 1 2 2 2 2 Ribosomal protein S2 CENP-H PF05837.12 CBK24595.2 - 7.2e-17 61.8 12.0 7.2e-17 61.8 12.0 2.1 2 0 0 2 2 2 1 Centromere protein H (CENP-H) DUF1403 PF07183.11 CBK24595.2 - 0.016 14.8 0.2 0.027 14.0 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1403) HALZ PF02183.18 CBK24595.2 - 0.096 12.9 8.7 0.27 11.5 2.2 3.1 2 0 0 2 2 2 0 Homeobox associated leucine zipper ASXH PF13919.6 CBK24595.2 - 0.13 12.2 4.1 0.25 11.4 4.1 1.4 1 0 0 1 1 1 0 Asx homology domain Utp12 PF04003.12 CBK24595.2 - 0.19 12.1 3.7 0.79 10.1 1.8 2.4 2 0 0 2 2 2 0 Dip2/Utp12 Family AAA_31 PF13614.6 CBK24595.2 - 6.9 6.5 7.6 7.6 6.4 0.3 2.2 1 1 1 2 2 2 0 AAA domain Amidohydro_2 PF04909.14 CBK24596.2 - 3.2e-37 128.9 0.7 3.6e-37 128.7 0.7 1.0 1 0 0 1 1 1 1 Amidohydrolase Peptidase_M19 PF01244.21 CBK24596.2 - 0.00015 21.1 0.0 0.00045 19.5 0.0 1.7 2 0 0 2 2 2 1 Membrane dipeptidase (Peptidase family M19) RRM_1 PF00076.22 CBK24598.2 - 9.6e-05 22.1 0.0 0.0014 18.4 0.0 2.3 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RSRP PF17069.5 CBK24598.2 - 0.0013 18.4 42.2 0.0018 17.9 42.2 1.3 1 0 0 1 1 1 1 Arginine/Serine-Rich protein 1 RRM_9 PF18444.1 CBK24598.2 - 0.03 14.2 0.0 0.28 11.1 0.0 2.1 1 1 0 1 1 1 0 RNA recognition motif DUF936 PF06075.12 CBK24598.2 - 0.058 12.3 18.6 0.07 12.0 18.6 1.0 1 0 0 1 1 1 0 Plant protein of unknown function (DUF936) Apt1 PF10351.9 CBK24598.2 - 0.082 11.7 15.7 0.091 11.6 15.7 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Zip PF02535.22 CBK24598.2 - 0.31 10.2 3.9 0.32 10.2 3.9 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter DUF2457 PF10446.9 CBK24598.2 - 0.68 9.0 22.9 0.9 8.6 22.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Macoilin PF09726.9 CBK24598.2 - 0.78 8.2 14.0 0.86 8.1 14.0 1.0 1 0 0 1 1 1 0 Macoilin family Presenilin PF01080.17 CBK24598.2 - 0.84 8.3 12.4 1 8.1 12.4 1.1 1 0 0 1 1 1 0 Presenilin PRP38_assoc PF12871.7 CBK24598.2 - 2.4 8.8 52.8 4.6 7.9 52.6 1.5 1 1 0 1 1 1 0 Pre-mRNA-splicing factor 38-associated hydrophilic C-term Ribosomal_L28 PF00830.19 CBK24600.2 - 3.4e-19 68.8 0.4 4.8e-19 68.3 0.4 1.2 1 0 0 1 1 1 1 Ribosomal L28 family Peptidase_M3 PF01432.20 CBK24600.2 - 0.0095 15.2 0.0 0.011 15.0 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M3 WD40 PF00400.32 CBK24601.2 - 7.1e-24 83.6 6.4 1.6e-05 25.5 0.1 6.1 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBK24601.2 - 1.3e-06 28.6 0.3 0.12 12.7 0.0 3.8 2 2 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain PALB2_WD40 PF16756.5 CBK24601.2 - 0.005 15.8 0.4 2.1 7.2 0.0 2.7 2 1 1 3 3 3 2 Partner and localizer of BRCA2 WD40 domain PQQ_2 PF13360.6 CBK24601.2 - 0.015 14.9 0.2 0.19 11.3 0.1 2.1 1 1 0 2 2 2 0 PQQ-like domain BBS2_Mid PF14783.6 CBK24601.2 - 0.023 14.7 0.0 2.1 8.4 0.0 2.7 2 1 0 2 2 2 0 Ciliary BBSome complex subunit 2, middle region Ge1_WD40 PF16529.5 CBK24601.2 - 0.026 13.5 0.2 0.3 10.0 0.0 2.4 1 1 2 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein PQQ_3 PF13570.6 CBK24601.2 - 1.5 9.4 4.7 35 5.0 0.3 4.1 5 0 0 5 5 5 0 PQQ-like domain Pkinase PF00069.25 CBK24602.2 - 1.9e-37 129.1 0.0 1.3e-18 67.3 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CBK24602.2 - 2.1e-07 30.5 0.0 0.0028 17.0 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase FTA2 PF13095.6 CBK24602.2 - 0.018 14.7 0.0 1.3 8.5 0.0 2.3 1 1 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Smoothelin PF12510.8 CBK24602.2 - 5.6 7.1 7.2 0.18 11.9 0.6 1.9 2 0 0 2 2 2 0 Smoothelin cytoskeleton protein Urocanase PF01175.18 CBK24603.2 - 6.5e-87 290.6 0.0 1.1e-86 289.9 0.0 1.3 1 0 0 1 1 1 1 Urocanase Rossmann-like domain Urocanase_C PF17392.2 CBK24603.2 - 7.8e-87 289.8 0.4 1.2e-86 289.2 0.4 1.3 1 0 0 1 1 1 1 Urocanase C-terminal domain Urocanase_N PF17391.2 CBK24603.2 - 2.6e-56 188.8 0.7 9.4e-56 187.0 0.5 2.0 2 0 0 2 2 2 1 Urocanase N-terminal domain Ldh_1_N PF00056.23 CBK24604.2 - 1.2e-29 103.2 0.1 2.1e-29 102.5 0.1 1.4 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.18 CBK24604.2 - 9.3e-29 100.5 0.0 1.3e-28 100.0 0.0 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain GNT-I PF03071.15 CBK24605.2 - 8.1e-93 311.5 0.1 9.7e-93 311.3 0.1 1.0 1 0 0 1 1 1 1 GNT-I family Bot1p PF12298.8 CBK24606.2 - 2.1e-05 24.8 0.1 2.1e-05 24.8 0.1 3.0 2 2 0 2 2 2 1 Eukaryotic mitochondrial regulator protein HTH_29 PF13551.6 CBK24606.2 - 0.013 15.6 0.0 0.79 9.8 0.1 2.7 2 0 0 2 2 2 0 Winged helix-turn helix HTH_23 PF13384.6 CBK24606.2 - 0.019 14.8 0.0 0.067 13.0 0.0 1.9 1 0 0 1 1 1 0 Homeodomain-like domain HTH_28 PF13518.6 CBK24606.2 - 0.025 14.7 0.0 0.13 12.4 0.0 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain Plasmodium_Vir PF05795.11 CBK24606.2 - 1.6 8.1 6.4 2.5 7.4 6.4 1.4 1 0 0 1 1 1 0 Plasmodium vivax Vir protein TRAP_alpha PF03896.16 CBK24606.2 - 1.7 7.7 0.0 1.7 7.7 0.0 3.0 2 1 0 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit Borrelia_P83 PF05262.11 CBK24606.2 - 1.9 6.9 11.9 3.1 6.2 11.9 1.3 1 0 0 1 1 1 0 Borrelia P83/100 protein Hydin_ADK PF17213.3 CBK24606.2 - 4.1 7.6 8.2 10 6.4 8.2 1.6 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain Presenilin PF01080.17 CBK24606.2 - 5.6 5.6 8.9 8.9 5.0 8.9 1.3 1 0 0 1 1 1 0 Presenilin CHCH PF06747.13 CBK24607.2 - 6.2e-07 29.4 3.3 6.2e-07 29.4 3.3 2.4 2 1 0 2 2 2 1 CHCH domain CX9C PF16860.5 CBK24607.2 - 0.00039 20.3 0.8 0.00039 20.3 0.8 2.2 2 0 0 2 2 2 1 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, Ndufs5 PF10200.9 CBK24607.2 - 0.033 14.4 3.8 0.097 12.9 3.8 1.7 1 1 0 1 1 1 0 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa Pet191_N PF10203.9 CBK24607.2 - 0.83 10.0 11.1 0.25 11.7 6.1 2.2 1 1 0 1 1 1 0 Cytochrome c oxidase assembly protein PET191 LSM PF01423.22 CBK24608.2 - 4.6e-15 55.0 0.0 5.2e-15 54.9 0.0 1.0 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 CBK24608.2 - 0.001 19.1 0.0 0.0011 19.1 0.0 1.1 1 0 0 1 1 1 1 Ataxin 2 SM domain UCH PF00443.29 CBK24609.2 - 2.4e-17 63.3 0.0 2.5e-16 60.0 0.0 2.1 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 CBK24609.2 - 0.00018 21.2 0.0 0.0014 18.3 0.0 2.1 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase Mpp10 PF04006.12 CBK24609.2 - 0.053 12.0 2.9 0.069 11.6 2.9 1.1 1 0 0 1 1 1 0 Mpp10 protein Torus PF16131.5 CBK24610.2 - 0.00066 20.3 0.1 0.0014 19.3 0.1 1.5 1 0 0 1 1 1 1 Torus domain zf_CCCH_4 PF18345.1 CBK24610.2 - 0.00079 19.4 2.3 0.0015 18.6 2.3 1.5 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH PF00642.24 CBK24610.2 - 0.0011 18.8 2.5 0.002 18.0 2.5 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.6 CBK24610.2 - 0.0054 17.2 1.7 0.0096 16.4 1.7 1.4 1 0 0 1 1 1 1 RNA-binding, Nab2-type zinc finger zf-CCCH_4 PF18044.1 CBK24610.2 - 0.019 14.7 2.7 0.034 14.0 2.7 1.4 1 0 0 1 1 1 0 CCCH-type zinc finger RRM_1 PF00076.22 CBK24611.2 - 7.1e-16 57.8 0.1 1.6e-15 56.7 0.1 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 CBK24611.2 - 0.0013 18.3 0.0 0.0026 17.4 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 CBK24611.2 - 0.02 14.9 0.1 0.043 13.8 0.1 1.5 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif RRM_7 PF16367.5 CBK24611.2 - 0.058 13.5 0.1 0.18 11.9 0.1 1.8 1 0 0 1 1 1 0 RNA recognition motif RRM_occluded PF16842.5 CBK24611.2 - 0.09 12.6 0.0 0.26 11.2 0.0 1.8 1 0 0 1 1 1 0 Occluded RNA-recognition motif Pep1_7 PF17232.2 CBK24611.2 - 2.5 8.6 8.2 34 5.0 5.7 2.5 2 0 0 2 2 2 0 Elicitor peptide 1-7 CTD_bind PF04818.13 CBK24612.2 - 0.0013 19.6 0.3 0.23 12.3 0.0 2.4 2 0 0 2 2 2 2 RNA polymerase II-binding domain. ABC_tran PF00005.27 CBK24613.2 - 3e-73 244.8 0.0 1.2e-37 129.5 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 CBK24613.2 - 3.4e-58 197.5 12.1 4.8e-31 108.4 2.2 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.19 CBK24613.2 - 2.6e-12 46.7 1.6 0.00026 20.5 0.2 4.2 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 CBK24613.2 - 4e-11 43.6 0.0 0.0006 20.2 0.0 3.1 2 1 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 CBK24613.2 - 4.1e-11 43.3 1.6 0.0011 19.3 0.0 4.1 2 2 0 2 2 2 2 AAA domain AAA PF00004.29 CBK24613.2 - 1.7e-09 38.2 0.2 0.00021 21.7 0.0 4.0 2 2 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.6 CBK24613.2 - 1.6e-08 34.2 0.4 0.0027 17.4 0.1 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_21 PF13304.6 CBK24613.2 - 3.1e-08 33.8 0.7 0.86 9.3 0.2 4.3 3 1 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 CBK24613.2 - 6.2e-08 32.7 0.0 0.017 15.0 0.0 2.7 2 0 0 2 2 2 2 RsgA GTPase G-alpha PF00503.20 CBK24613.2 - 2.4e-06 26.9 0.0 0.047 12.8 0.0 2.4 2 0 0 2 2 2 2 G-protein alpha subunit ABC_ATPase PF09818.9 CBK24613.2 - 3.3e-06 26.2 1.3 0.02 13.7 0.0 2.9 3 0 0 3 3 3 2 Predicted ATPase of the ABC class AAA_25 PF13481.6 CBK24613.2 - 3.4e-06 26.8 0.2 0.49 9.9 0.0 4.0 4 0 0 4 4 4 2 AAA domain AAA_30 PF13604.6 CBK24613.2 - 3.5e-06 26.9 0.5 0.22 11.2 0.2 3.9 3 1 0 3 3 3 2 AAA domain AAA_5 PF07728.14 CBK24613.2 - 6e-06 26.3 0.7 0.81 9.7 0.0 4.3 4 0 0 4 4 4 1 AAA domain (dynein-related subfamily) AAA_23 PF13476.6 CBK24613.2 - 9.2e-06 26.3 7.9 0.03 14.8 0.0 3.4 3 0 0 3 3 3 2 AAA domain SbcCD_C PF13558.6 CBK24613.2 - 1.2e-05 25.4 3.9 0.065 13.5 0.6 3.7 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit TniB PF05621.11 CBK24613.2 - 3.9e-05 23.2 0.2 4.8 6.5 0.0 4.2 4 0 0 4 4 4 0 Bacterial TniB protein AAA_7 PF12775.7 CBK24613.2 - 0.00011 21.8 0.1 0.13 11.7 0.0 2.6 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_18 PF13238.6 CBK24613.2 - 0.00022 21.8 6.0 0.71 10.4 0.0 4.3 5 0 0 5 5 4 2 AAA domain IstB_IS21 PF01695.17 CBK24613.2 - 0.00022 21.0 0.1 1.7 8.4 0.0 3.8 4 0 0 4 4 3 1 IstB-like ATP binding protein RNA_helicase PF00910.22 CBK24613.2 - 0.00024 21.5 0.0 1.2 9.5 0.0 3.5 3 0 0 3 3 3 1 RNA helicase MMR_HSR1 PF01926.23 CBK24613.2 - 0.00028 21.0 1.0 0.59 10.2 0.0 3.3 3 0 0 3 3 2 1 50S ribosome-binding GTPase Rad17 PF03215.15 CBK24613.2 - 0.00031 20.7 0.0 0.14 12.1 0.0 2.5 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_15 PF13175.6 CBK24613.2 - 0.00067 19.5 5.7 0.45 10.2 0.0 3.1 3 0 0 3 3 3 2 AAA ATPase domain NB-ARC PF00931.22 CBK24613.2 - 0.00071 18.8 0.1 1.1 8.4 0.0 2.8 2 0 0 2 2 2 2 NB-ARC domain DEAD PF00270.29 CBK24613.2 - 0.0013 18.6 0.4 0.22 11.2 0.1 3.4 2 2 0 2 2 2 1 DEAD/DEAH box helicase PRK PF00485.18 CBK24613.2 - 0.0017 18.1 0.2 0.51 10.0 0.1 2.4 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family AAA_33 PF13671.6 CBK24613.2 - 0.0019 18.4 0.2 1.8 8.7 0.1 2.8 2 1 0 2 2 2 1 AAA domain AAA_24 PF13479.6 CBK24613.2 - 0.0024 17.6 0.4 1.3 8.7 0.1 3.0 2 2 0 2 2 2 1 AAA domain Sigma54_activat PF00158.26 CBK24613.2 - 0.0055 16.4 0.0 4.9 6.8 0.0 3.3 3 0 0 3 3 3 0 Sigma-54 interaction domain Roc PF08477.13 CBK24613.2 - 0.0079 16.4 0.0 4.1 7.6 0.0 3.4 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase ATP_bind_1 PF03029.17 CBK24613.2 - 0.0095 15.7 0.5 0.68 9.7 0.1 2.7 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein MeaB PF03308.16 CBK24613.2 - 0.011 14.8 0.0 0.59 9.1 0.0 2.5 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Zeta_toxin PF06414.12 CBK24613.2 - 0.012 14.9 0.0 3.8 6.7 0.0 2.6 2 0 0 2 2 2 0 Zeta toxin DUF87 PF01935.17 CBK24613.2 - 0.014 15.5 3.7 0.25 11.4 0.0 3.2 3 0 0 3 3 3 0 Helicase HerA, central domain KAP_NTPase PF07693.14 CBK24613.2 - 0.016 14.5 0.0 0.25 10.6 0.0 2.4 2 0 0 2 2 2 0 KAP family P-loop domain MoaE PF02391.17 CBK24613.2 - 0.016 15.5 1.2 5.9 7.2 0.1 3.6 3 1 0 3 3 2 0 MoaE protein DUF815 PF05673.13 CBK24613.2 - 0.018 14.2 0.0 1.2 8.2 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_28 PF13521.6 CBK24613.2 - 0.022 15.0 0.8 4.1 7.6 0.0 3.5 3 0 0 3 3 3 0 AAA domain Mg_chelatase PF01078.21 CBK24613.2 - 0.025 13.9 0.0 2.7 7.3 0.0 2.7 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI NACHT PF05729.12 CBK24613.2 - 0.03 14.3 0.1 2.2 8.2 0.1 2.7 2 0 0 2 2 2 0 NACHT domain APS_kinase PF01583.20 CBK24613.2 - 0.036 13.9 0.1 4 7.3 0.0 2.8 3 0 0 3 3 2 0 Adenylylsulphate kinase AAA_14 PF13173.6 CBK24613.2 - 0.044 13.8 0.0 17 5.5 0.0 3.1 3 0 0 3 3 2 0 AAA domain NTPase_1 PF03266.15 CBK24613.2 - 0.045 13.7 1.8 3.9 7.4 0.0 3.0 4 0 0 4 4 2 0 NTPase ECH_2 PF16113.5 CBK24613.2 - 0.048 13.2 0.1 16 4.9 0.0 3.0 3 0 0 3 3 3 0 Enoyl-CoA hydratase/isomerase MobB PF03205.14 CBK24613.2 - 0.063 13.2 0.1 5.3 7.0 0.1 2.8 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_17 PF13207.6 CBK24613.2 - 0.081 13.3 0.7 19 5.7 0.0 3.6 3 0 0 3 3 3 0 AAA domain AAA_19 PF13245.6 CBK24613.2 - 0.088 13.1 4.5 8.2 6.8 0.1 4.5 4 2 0 4 4 4 0 AAA domain ATP-synt_ab PF00006.25 CBK24613.2 - 0.13 11.9 0.0 11 5.6 0.0 2.5 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain DUF4604 PF15377.6 CBK24613.2 - 0.59 10.5 4.0 1.3 9.4 4.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4604) AAA_23 PF13476.6 CBK24614.2 - 9.2e-17 62.2 0.0 1.2e-16 61.8 0.0 1.1 1 0 0 1 1 1 1 AAA domain SMC_N PF02463.19 CBK24614.2 - 1.2e-15 57.6 0.1 1.2e-15 57.6 0.1 1.1 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 CBK24614.2 - 8.1e-06 25.8 0.1 9.5e-06 25.6 0.1 1.1 1 0 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 CBK24614.2 - 0.00014 21.6 0.0 0.00023 20.9 0.0 1.3 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_13 PF13166.6 CBK24614.2 - 0.0044 15.8 0.0 0.0062 15.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_27 PF13514.6 CBK24614.2 - 0.018 14.7 0.0 0.035 13.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 CBK24614.2 - 0.018 15.5 0.9 0.037 14.5 0.9 1.8 1 1 0 1 1 1 0 ABC transporter MukB PF04310.12 CBK24614.2 - 0.043 13.6 0.0 0.043 13.6 0.0 1.2 1 0 0 1 1 1 0 MukB N-terminal AAA_21 PF13304.6 CBK24614.2 - 0.045 13.6 2.2 0.089 12.6 2.2 1.8 1 1 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system Zeta_toxin PF06414.12 CBK24614.2 - 0.1 11.8 0.0 0.18 11.0 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin MOZ_SAS PF01853.18 CBK24615.2 - 4.5e-76 254.5 0.4 5.9e-76 254.1 0.4 1.1 1 0 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 CBK24615.2 - 1.6e-21 75.6 7.0 1.6e-21 75.6 7.0 2.4 2 1 1 3 3 3 1 MYST family zinc finger domain zf-C2H2_jaz PF12171.8 CBK24615.2 - 0.0028 17.9 0.8 0.0076 16.5 0.8 1.8 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.6 CBK24615.2 - 0.045 14.6 0.4 0.045 14.6 0.4 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger Acetyltransf_1 PF00583.25 CBK24615.2 - 0.14 12.4 0.0 0.26 11.5 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family zf-C2H2_6 PF13912.6 CBK24615.2 - 0.14 12.2 0.7 0.25 11.4 0.7 1.4 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2H2 PF00096.26 CBK24615.2 - 0.27 11.8 0.3 0.27 11.8 0.3 2.4 2 0 0 2 2 2 0 Zinc finger, C2H2 type CDC24 PF06395.11 CBK24616.2 - 0.0028 17.9 0.1 0.02 15.2 0.0 2.1 1 1 1 2 2 2 1 CDC24 Calponin GTP_EFTU PF00009.27 CBK24616.2 - 0.016 14.7 0.0 0.026 14.1 0.0 1.2 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 CBK24616.2 - 0.098 12.6 0.1 0.2 11.5 0.1 1.5 1 1 0 1 1 1 0 RsgA GTPase Nop53 PF07767.11 CBK24617.2 - 1.7e-08 34.3 21.3 2e-08 34.0 21.3 1.0 1 0 0 1 1 1 1 Nop53 (60S ribosomal biogenesis) FAM220 PF15487.6 CBK24617.2 - 0.002 17.8 3.5 0.0025 17.5 3.5 1.1 1 0 0 1 1 1 1 FAM220 family GST_N PF02798.20 CBK24617.2 - 0.12 12.8 0.3 0.22 11.9 0.2 1.5 1 1 0 1 1 1 0 Glutathione S-transferase, N-terminal domain CDC45 PF02724.14 CBK24617.2 - 0.81 7.9 13.7 0.93 7.7 13.7 1.0 1 0 0 1 1 1 0 CDC45-like protein Presenilin PF01080.17 CBK24617.2 - 1.6 7.5 10.9 1.8 7.2 10.9 1.0 1 0 0 1 1 1 0 Presenilin Nup88 PF10168.9 CBK24617.2 - 3 5.5 10.7 3.5 5.3 10.7 1.1 1 0 0 1 1 1 0 Nuclear pore component WDCP PF15390.6 CBK24617.2 - 3.5 5.9 5.8 4 5.7 5.8 1.0 1 0 0 1 1 1 0 WD repeat and coiled-coil-containing protein family Neur_chan_memb PF02932.16 CBK24617.2 - 6 6.9 4.9 7 6.6 4.9 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Metallophos PF00149.28 CBK24618.2 - 9.7e-26 91.5 0.0 1.6e-25 90.8 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Cation_ATPase_C PF00689.21 CBK24619.2 - 4.8e-42 143.7 13.0 4.8e-42 143.7 13.0 2.4 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 CBK24619.2 - 3.5e-40 137.4 3.5 3.5e-40 137.4 3.5 3.3 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.26 CBK24619.2 - 1.3e-18 68.0 0.0 3.2e-14 53.7 0.0 2.9 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 CBK24619.2 - 5e-15 55.3 0.0 1.1e-14 54.3 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 CBK24619.2 - 0.009 15.8 0.2 0.1 12.4 0.3 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase PA14 PF07691.12 CBK24620.2 - 3.7e-15 56.0 1.2 2.4e-08 33.9 0.1 2.8 2 0 0 2 2 2 2 PA14 domain He_PIG PF05345.12 CBK24620.2 - 6.6e-12 45.4 17.3 3e-05 24.1 0.7 5.3 5 0 0 5 5 5 3 Putative Ig domain GLEYA PF10528.9 CBK24620.2 - 1.2e-07 32.0 0.7 0.00053 20.4 0.4 2.9 2 0 0 2 2 2 2 GLEYA domain DUF5354 PF17305.2 CBK24620.2 - 0.046 13.9 0.1 0.13 12.5 0.1 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5354) He_PIG PF05345.12 CBK24621.2 - 8.2e-06 25.9 0.8 1.3e-05 25.3 0.8 1.3 1 0 0 1 1 1 1 Putative Ig domain Med31 PF05669.12 CBK24622.2 - 2.5e-32 110.7 10.7 3.4e-32 110.3 10.7 1.1 1 0 0 1 1 1 1 SOH1 Ribosomal_S19e PF01090.19 CBK24623.2 - 7.8e-35 119.5 0.0 8.5e-35 119.4 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S19e DUF2398 PF09661.10 CBK24623.2 - 0.038 13.2 0.0 0.04 13.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2398) HrcA_DNA-bdg PF03444.15 CBK24623.2 - 0.06 13.0 0.0 0.1 12.2 0.0 1.4 1 0 0 1 1 1 0 Winged helix-turn-helix transcription repressor, HrcA DNA-binding Ribosomal_L40e PF01020.17 CBK24624.2 - 4.1e-29 100.2 13.8 4.1e-29 100.2 13.8 1.7 2 0 0 2 2 2 1 Ribosomal L40e family ubiquitin PF00240.23 CBK24624.2 - 5.1e-18 64.6 0.0 6.8e-18 64.2 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 CBK24624.2 - 5.7e-10 38.9 0.1 8.7e-10 38.3 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF866 PF05907.13 CBK24625.2 - 6.8e-27 94.3 5.3 1.1e-25 90.3 5.3 2.3 1 1 0 1 1 1 1 Eukaryotic protein of unknown function (DUF866) zinc_ribbon_4 PF13717.6 CBK24625.2 - 0.12 12.3 5.8 0.44 10.5 1.3 2.4 2 0 0 2 2 2 0 zinc-ribbon domain RNR_Alpha PF17975.1 CBK24626.2 - 1.7e-38 131.2 0.0 6e-38 129.4 0.1 2.0 2 0 0 2 2 2 1 Ribonucleotide reductase alpha domain Ribonuc_red_lgC PF02867.15 CBK24626.2 - 1.3e-08 33.9 0.0 0.00084 18.0 0.0 3.1 3 0 0 3 3 3 3 Ribonucleotide reductase, barrel domain Glycos_transf_1 PF00534.20 CBK24627.2 - 1e-10 41.5 0.0 1.9e-10 40.6 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 CBK24627.2 - 3e-06 27.7 0.0 6e-06 26.7 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 CBK24627.2 - 0.00025 21.4 0.0 0.00068 20.0 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 DUF3135 PF11333.8 CBK24627.2 - 0.011 15.9 0.2 0.021 15.1 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3135) Pkinase PF00069.25 CBK24628.2 - 2.5e-19 69.7 0.0 2.8e-19 69.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBK24628.2 - 7.9e-10 38.4 0.0 8.7e-10 38.3 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase FKBP_C PF00254.28 CBK24629.2 - 3.6e-09 36.8 0.0 6.9e-09 35.9 0.0 1.5 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase NPL PF17800.1 CBK24629.2 - 6.6e-05 23.4 0.0 0.00011 22.7 0.0 1.4 1 0 0 1 1 1 1 Nucleoplasmin-like domain PH_3 PF14593.6 CBK24629.2 - 0.0018 18.3 0.0 0.0049 17.0 0.0 1.6 1 1 0 1 1 1 1 PH domain Glyco_transf_49 PF13896.6 CBK24630.2 - 6.4e-07 29.0 0.4 0.016 14.6 0.0 2.6 1 1 1 2 2 2 2 Glycosyl-transferase for dystroglycan Adap_comp_sub PF00928.21 CBK24631.2 - 2e-36 125.7 0.0 2.8e-36 125.3 0.0 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 CBK24631.2 - 2.3e-06 27.6 0.3 3.5e-06 27.0 0.3 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain LRR_8 PF13855.6 CBK24632.2 - 0.0008 19.1 0.5 0.11 12.3 0.0 3.8 3 1 1 4 4 4 1 Leucine rich repeat Trypan_PARP PF05887.11 CBK24632.2 - 0.083 12.9 1.2 0.14 12.1 1.2 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) SVS_QK PF10578.9 CBK24632.2 - 0.62 10.8 5.5 2.9 8.7 1.6 3.2 2 0 0 2 2 2 0 Seminal vesicle protein repeat NESP55 PF06390.12 CBK24632.2 - 9.7 5.7 7.3 15 5.1 7.3 1.2 1 0 0 1 1 1 0 Neuroendocrine-specific golgi protein P55 (NESP55) HEAT_2 PF13646.6 CBK24635.2 - 2.5e-11 43.8 10.3 0.0059 17.0 0.0 8.0 5 3 4 9 9 9 4 HEAT repeats HEAT PF02985.22 CBK24635.2 - 2.8e-11 42.7 10.4 0.0019 18.3 0.0 9.7 11 0 0 11 11 10 3 HEAT repeat Importin_rep_4 PF18808.1 CBK24635.2 - 5.2e-09 36.3 2.7 1.6e-07 31.5 0.0 4.3 4 1 0 5 5 4 1 Importin repeat ParcG PF10274.9 CBK24635.2 - 9.3e-07 29.1 1.3 0.04 14.0 0.0 4.0 4 0 0 4 4 4 2 Parkin co-regulated protein HEAT_EZ PF13513.6 CBK24635.2 - 1.5e-06 28.5 11.2 0.13 12.8 0.0 8.4 7 1 1 8 8 8 1 HEAT-like repeat IBN_N PF03810.19 CBK24635.2 - 2.9e-05 23.9 6.8 0.0068 16.3 0.6 4.5 4 0 0 4 4 4 1 Importin-beta N-terminal domain Vac14_Fab1_bd PF12755.7 CBK24635.2 - 0.0099 16.5 0.5 2.2 8.9 0.0 4.3 3 1 1 4 4 4 1 Vacuolar 14 Fab1-binding region DUF3361 PF11841.8 CBK24635.2 - 0.011 15.7 0.6 0.071 13.1 0.4 2.6 2 0 0 2 2 1 0 Domain of unknown function (DUF3361) Adaptin_N PF01602.20 CBK24635.2 - 0.011 14.4 14.2 0.036 12.6 5.1 4.7 2 1 4 6 6 6 0 Adaptin N terminal region MMS19_N PF14500.6 CBK24635.2 - 0.029 14.0 6.4 0.07 12.7 0.9 3.7 4 2 1 5 5 5 0 Dos2-interacting transcription regulator of RNA-Pol-II DUF4042 PF13251.6 CBK24635.2 - 0.033 13.9 2.5 2.2 8.0 0.0 4.3 3 1 1 4 4 4 0 Domain of unknown function (DUF4042) V-ATPase_H_N PF03224.14 CBK24635.2 - 0.07 12.4 6.3 0.062 12.6 1.6 3.3 3 1 0 3 3 3 0 V-ATPase subunit H SARS_lipid_bind PF09399.10 CBK24635.2 - 0.11 12.7 0.0 0.38 10.9 0.0 1.9 1 0 0 1 1 1 0 SARS lipid binding protein DUF3385 PF11865.8 CBK24635.2 - 0.12 12.3 10.8 65 3.4 0.2 6.7 5 2 0 6 6 6 0 Domain of unknown function (DUF3385) HEAT_PBS PF03130.16 CBK24635.2 - 0.24 12.2 3.0 22 6.1 0.0 5.6 6 0 0 6 6 4 0 PBS lyase HEAT-like repeat Urb2 PF10441.9 CBK24635.2 - 2.6 7.9 8.7 0.88 9.5 2.5 3.2 3 1 0 3 3 3 0 Urb2/Npa2 family Arm PF00514.23 CBK24635.2 - 5.2 7.3 13.7 16 5.7 0.0 6.9 7 1 0 7 7 7 0 Armadillo/beta-catenin-like repeat RNase_PH PF01138.21 CBK24636.2 - 1.3e-15 58.0 0.0 1.9e-15 57.5 0.0 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 CBK24636.2 - 0.0013 18.7 0.0 0.0038 17.2 0.0 1.8 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 Ribosomal_S24e PF01282.19 CBK24637.2 - 2.9e-28 97.6 0.1 6.2e-28 96.6 0.0 1.6 1 1 0 1 1 1 1 Ribosomal protein S24e CAS_CSE1 PF03378.15 CBK24638.2 - 1.4e-13 50.1 0.1 1.8e-13 49.8 0.1 1.0 1 0 0 1 1 1 1 CAS/CSE protein, C-terminus Utp13 PF08625.11 CBK24638.2 - 0.014 15.3 0.2 1 9.2 0.0 2.4 3 0 0 3 3 3 0 Utp13 specific WD40 associated domain DUF3452 PF11934.8 CBK24639.2 - 0.11 12.0 1.6 0.17 11.4 1.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3452) Zip PF02535.22 CBK24640.2 - 0.058 12.6 0.3 0.068 12.4 0.3 1.0 1 0 0 1 1 1 0 ZIP Zinc transporter DUF2813 PF11398.8 CBK24640.2 - 0.073 12.3 0.4 0.083 12.1 0.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2813) AP3D1 PF06375.11 CBK24640.2 - 0.11 12.8 5.4 0.13 12.5 5.4 1.2 1 0 0 1 1 1 0 AP-3 complex subunit delta-1 DUF3043 PF11241.8 CBK24640.2 - 6.4 6.8 6.4 8.9 6.3 6.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3043) Mitofilin PF09731.9 CBK24642.2 - 0.0021 17.0 34.5 0.033 13.0 0.0 3.0 2 1 1 3 3 3 2 Mitochondrial inner membrane protein DUF2433 PF10360.9 CBK24642.2 - 0.16 12.0 1.0 0.5 10.5 1.0 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2433) DUF3022 PF11226.8 CBK24642.2 - 0.24 11.9 3.3 17 5.9 0.3 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3022) PPR_2 PF13041.6 CBK24643.2 - 4.4e-43 145.3 5.6 6.8e-08 32.6 0.1 8.8 6 2 4 10 10 10 7 PPR repeat family PPR PF01535.20 CBK24643.2 - 7.4e-31 104.2 10.9 0.00088 19.4 0.0 8.9 9 0 0 9 9 9 7 PPR repeat PPR_3 PF13812.6 CBK24643.2 - 3.8e-28 97.3 0.9 6.3e-07 29.4 0.1 7.2 5 2 1 7 7 7 5 Pentatricopeptide repeat domain PPR_long PF17177.4 CBK24643.2 - 5.6e-19 68.3 3.1 5.5e-10 39.0 0.3 3.1 2 1 1 3 3 3 3 Pentacotripeptide-repeat region of PRORP PPR_1 PF12854.7 CBK24643.2 - 1.5e-17 63.0 4.3 0.017 14.8 0.0 8.6 9 1 1 10 10 10 5 PPR repeat TPR_19 PF14559.6 CBK24643.2 - 4.6e-05 23.8 0.0 1 9.9 0.0 4.9 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_14 PF13428.6 CBK24643.2 - 0.00063 20.3 0.1 21 6.2 0.0 4.7 6 0 0 6 6 4 0 Tetratricopeptide repeat MRP-S27 PF10037.9 CBK24643.2 - 0.001 18.0 0.2 0.0022 16.9 0.2 1.5 1 0 0 1 1 1 1 Mitochondrial 28S ribosomal protein S27 Clathrin PF00637.20 CBK24643.2 - 0.0024 17.8 0.2 0.3 11.0 0.0 3.7 3 1 1 4 4 4 1 Region in Clathrin and VPS Exog_C PF18026.1 CBK24643.2 - 0.0039 17.2 0.0 0.2 11.8 0.0 2.9 3 0 0 3 3 3 1 Endo/exonuclease (EXOG) C-terminal domain Sulfotransfer_1 PF00685.27 CBK24643.2 - 0.016 14.7 0.1 0.029 13.9 0.1 1.4 1 0 0 1 1 1 0 Sulfotransferase domain ATP13 PF12921.7 CBK24643.2 - 0.17 11.8 0.1 93 2.9 0.0 4.0 2 1 2 5 5 5 0 Mitochondrial ATPase expression Y_phosphatase2 PF03162.13 CBK24644.2 - 2.4e-36 124.8 0.0 2.8e-36 124.6 0.0 1.0 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 CBK24644.2 - 0.0022 17.6 0.0 0.0029 17.2 0.0 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 CBK24644.2 - 0.1 12.5 0.0 0.13 12.2 0.0 1.2 1 0 0 1 1 1 0 Tyrosine phosphatase family RRM_1 PF00076.22 CBK24645.2 - 4.8e-12 45.5 0.1 1.5e-10 40.7 0.1 2.4 2 1 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CSTF2_hinge PF14327.6 CBK24645.2 - 3.8e-05 24.0 0.0 0.00011 22.6 0.0 1.7 2 0 0 2 2 2 1 Hinge domain of cleavage stimulation factor subunit 2 Pox_A3L PF05288.11 CBK24645.2 - 0.011 15.6 0.2 0.033 14.2 0.2 1.8 2 0 0 2 2 2 0 Poxvirus A3L Protein RRM_Rrp7 PF17799.1 CBK24645.2 - 0.067 13.0 0.0 0.62 9.8 0.0 2.2 2 1 1 3 3 3 0 Rrp7 RRM-like N-terminal domain Spo7_2_N PF15407.6 CBK24645.2 - 0.12 12.1 0.0 0.23 11.1 0.0 1.5 1 0 0 1 1 1 0 Sporulation protein family 7 Sin3_corepress PF08295.12 CBK24646.2 - 1e-26 92.9 0.0 2.2e-26 91.8 0.0 1.5 1 0 0 1 1 1 1 Sin3 family co-repressor CENP-K PF11802.8 CBK24646.2 - 0.039 13.5 0.5 0.052 13.1 0.5 1.1 1 0 0 1 1 1 0 Centromere-associated protein K HSP70 PF00012.20 CBK24647.2 - 3.9e-266 884.0 6.8 4.5e-266 883.8 6.8 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 CBK24647.2 - 9.2e-20 70.7 0.3 1.5e-18 66.7 0.1 2.1 2 0 0 2 2 2 1 MreB/Mbl protein DDR PF08841.10 CBK24647.2 - 0.0032 16.5 0.3 0.061 12.3 0.1 2.3 2 0 0 2 2 2 1 Diol dehydratase reactivase ATPase-like domain PilM_2 PF11104.8 CBK24647.2 - 0.016 14.3 0.2 0.33 9.9 0.0 2.5 3 0 0 3 3 3 0 Type IV pilus assembly protein PilM; BcrAD_BadFG PF01869.20 CBK24647.2 - 0.023 14.2 0.1 7.9 5.9 0.1 2.5 2 0 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family Hydantoinase_A PF01968.18 CBK24647.2 - 0.028 13.7 0.1 0.066 12.5 0.1 1.7 1 0 0 1 1 1 0 Hydantoinase/oxoprolinase FGGY_C PF02782.16 CBK24647.2 - 0.046 13.4 0.0 0.083 12.6 0.0 1.4 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain FKS1_dom1 PF14288.6 CBK24647.2 - 0.13 12.6 0.1 11 6.3 0.0 2.4 2 0 0 2 2 2 0 1,3-beta-glucan synthase subunit FKS1, domain-1 Carboxyl_trans PF01039.22 CBK24649.2 - 4.9e-190 632.4 0.1 5.8e-190 632.1 0.1 1.0 1 0 0 1 1 1 1 Carboxyl transferase domain MdcE PF06833.11 CBK24649.2 - 0.0093 15.5 0.0 0.03 13.8 0.0 1.8 3 0 0 3 3 3 1 Malonate decarboxylase gamma subunit (MdcE) Kin17_mid PF10357.9 CBK24650.2 - 6e-41 139.3 1.4 6e-41 139.3 1.4 2.0 2 0 0 2 2 2 1 Domain of Kin17 curved DNA-binding protein KN17_SH3 PF18131.1 CBK24650.2 - 0.00048 20.2 1.5 0.001 19.1 1.5 1.6 1 0 0 1 1 1 1 KN17 SH3-like C-terminal domain Rhabdo_glycop PF00974.18 CBK24651.2 - 0.039 12.4 0.0 0.058 11.8 0.0 1.2 1 0 0 1 1 1 0 Rhabdovirus spike glycoprotein DUF5389 PF17364.2 CBK24651.2 - 0.086 12.9 0.0 0.33 11.0 0.0 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF5389) IP_trans PF02121.18 CBK24652.2 - 1e-60 205.4 0.0 1.5e-60 204.9 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylinositol transfer protein EamA PF00892.20 CBK24652.2 - 7.2e-05 23.0 4.6 7.2e-05 23.0 4.6 3.8 3 1 1 4 4 4 2 EamA-like transporter family Vut_1 PF02592.15 CBK24652.2 - 0.015 15.7 3.3 0.015 15.7 3.3 2.4 2 0 0 2 2 2 0 Putative vitamin uptake transporter Col_cuticle_N PF01484.17 CBK24652.2 - 0.14 12.2 1.6 0.68 10.0 1.6 2.2 1 0 0 1 1 1 0 Nematode cuticle collagen N-terminal domain Tim17 PF02466.19 CBK24655.2 - 2.7e-23 82.4 2.5 3e-23 82.3 1.6 1.5 1 1 1 2 2 2 1 Tim17/Tim22/Tim23/Pmp24 family Oxysterol_BP PF01237.18 CBK24656.2 - 2.8e-69 233.7 0.0 2.7e-67 227.2 0.0 2.0 1 1 0 1 1 1 1 Oxysterol-binding protein PRA1 PF03208.19 CBK24657.2 - 7.6e-17 61.3 11.4 9.4e-17 61.0 11.4 1.1 1 0 0 1 1 1 1 PRA1 family protein DUF3488 PF11992.8 CBK24657.2 - 2.7 6.8 9.9 3.5 6.5 9.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3488) DUF2070 PF09843.9 CBK24657.2 - 9.8 4.3 10.6 12 4.0 10.6 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) UBX PF00789.20 CBK24658.2 - 4.6e-05 23.5 0.0 7.9e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 UBX domain ROK PF00480.20 CBK24660.2 - 1e-42 146.7 5.6 1.3e-42 146.3 5.6 1.1 1 0 0 1 1 1 1 ROK family BcrAD_BadFG PF01869.20 CBK24660.2 - 1.9e-07 30.9 0.4 2.7e-07 30.4 0.4 1.4 1 0 0 1 1 1 1 BadF/BadG/BcrA/BcrD ATPase family FGGY_N PF00370.21 CBK24660.2 - 2.8e-05 23.8 0.0 5.8e-05 22.8 0.0 1.5 1 1 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain Ribosomal_L22 PF00237.19 CBK24661.2 - 2.3e-33 114.5 0.2 3.9e-33 113.8 0.2 1.4 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e tRNA_m1G_MT PF01746.21 CBK24662.2 - 7.9e-18 64.9 0.0 2.8e-17 63.1 0.0 1.8 2 0 0 2 2 2 1 tRNA (Guanine-1)-methyltransferase dsrm PF00035.26 CBK24662.2 - 8.8e-05 23.1 1.6 0.00038 21.1 1.6 2.1 1 1 0 1 1 1 1 Double-stranded RNA binding motif NUDIX PF00293.28 CBK24663.2 - 1.5e-20 73.6 0.0 1.9e-20 73.2 0.0 1.1 1 0 0 1 1 1 1 NUDIX domain TRAP-gamma PF07074.12 CBK24664.2 - 3.4e-05 23.5 8.0 0.0031 17.1 0.8 2.1 1 1 1 2 2 2 2 Translocon-associated protein, gamma subunit (TRAP-gamma) PrgI PF12666.7 CBK24664.2 - 0.0043 17.7 3.4 0.005 17.5 0.1 2.1 2 0 0 2 2 2 1 PrgI family protein EVI2A PF05399.11 CBK24666.2 - 0.015 14.9 0.3 0.035 13.7 0.2 1.6 1 1 1 2 2 2 0 Ectropic viral integration site 2A protein (EVI2A) DUF5383 PF17355.2 CBK24666.2 - 0.021 15.2 1.2 0.059 13.8 0.9 1.9 1 1 1 2 2 2 0 Family of unknown function (DUF5383) PDR_assoc PF08370.11 CBK24666.2 - 0.07 12.9 0.0 0.29 10.9 0.0 2.0 2 0 0 2 2 2 0 Plant PDR ABC transporter associated FYVE PF01363.21 CBK24667.2 - 1e-17 64.0 17.0 1e-17 64.0 17.0 2.0 2 1 0 2 2 2 1 FYVE zinc finger ATP-synt_ab PF00006.25 CBK24668.2 - 1.3e-65 221.0 0.0 1.8e-65 220.6 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 CBK24668.2 - 6.5e-10 39.4 0.4 1.2e-09 38.6 0.4 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain HAS-barrel PF09378.10 CBK24668.2 - 0.029 14.5 0.1 0.069 13.3 0.1 1.7 1 0 0 1 1 1 0 HAS barrel domain Pro_isomerase PF00160.21 CBK24670.2 - 4.2e-38 131.1 0.1 7.8e-38 130.2 0.1 1.4 1 1 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD MFAP1 PF06991.11 CBK24671.2 - 1.9e-44 152.1 26.0 2.3e-44 151.9 26.0 1.1 1 0 0 1 1 1 1 Microfibril-associated/Pre-mRNA processing DUF4718 PF15842.5 CBK24671.2 - 1.4 8.6 5.7 0.21 11.4 0.9 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4718) CDC45 PF02724.14 CBK24671.2 - 2.3 6.4 19.4 2.8 6.1 19.4 1.1 1 0 0 1 1 1 0 CDC45-like protein CorA PF01544.18 CBK24673.2 - 3.7e-15 56.0 0.7 4.2e-15 55.8 0.7 1.0 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein Mem_trans PF03547.18 CBK24673.2 - 0.1 11.0 1.2 0.12 10.7 1.2 1.1 1 0 0 1 1 1 0 Membrane transport protein RRP36 PF06102.12 CBK24674.2 - 8e-42 143.0 40.5 1e-41 142.7 40.5 1.0 1 0 0 1 1 1 1 rRNA biogenesis protein RRP36 COMMD1_N PF17221.3 CBK24674.2 - 2.5 8.5 10.4 0.22 11.8 5.4 1.8 2 1 0 2 2 2 0 COMMD1 N-terminal domain NTF2 PF02136.20 CBK24675.2 - 7.5e-11 42.7 0.0 1.7e-10 41.5 0.0 1.6 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain RRM_1 PF00076.22 CBK24675.2 - 1.1e-07 31.5 0.3 2.5e-07 30.4 0.3 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Med20 PF08612.11 CBK24675.2 - 0.00022 20.7 0.1 0.00055 19.4 0.1 1.6 1 0 0 1 1 1 1 TATA-binding related factor (TRF) of subunit 20 of Mediator complex RRM_3 PF08777.11 CBK24675.2 - 0.023 14.7 0.1 0.023 14.7 0.1 2.0 2 0 0 2 2 2 0 RNA binding motif Nup35_RRM_2 PF14605.6 CBK24675.2 - 0.076 13.0 0.1 0.22 11.6 0.1 1.8 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Borrelia_P83 PF05262.11 CBK24675.2 - 0.21 10.0 6.8 0.27 9.7 6.8 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein TFIIA PF03153.13 CBK24675.2 - 9 6.2 19.1 13 5.7 19.1 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CDC50 PF03381.15 CBK24676.2 - 1.1e-44 153.1 0.0 1.2e-44 152.9 0.0 1.0 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family He_PIG PF05345.12 CBK24678.2 - 6.8e-07 29.4 0.2 1.7e-06 28.1 0.2 1.6 1 0 0 1 1 1 1 Putative Ig domain Tmemb_9 PF05434.11 CBK24678.2 - 0.033 14.1 0.2 0.05 13.5 0.2 1.2 1 0 0 1 1 1 0 TMEM9 ASFV_J13L PF05568.11 CBK24678.2 - 0.044 13.5 0.9 0.089 12.5 0.9 1.5 1 0 0 1 1 1 0 African swine fever virus J13L protein Orf78 PF06024.12 CBK24678.2 - 0.096 13.0 0.1 0.16 12.3 0.1 1.3 1 0 0 1 1 1 0 Orf78 (ac78) HemY_N PF07219.13 CBK24678.2 - 0.097 12.9 1.1 0.2 11.8 0.6 1.7 2 0 0 2 2 2 0 HemY protein N-terminus DUF4834 PF16118.5 CBK24678.2 - 0.21 12.6 0.3 0.32 12.0 0.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) EphA2_TM PF14575.6 CBK24678.2 - 0.29 12.0 1.3 0.55 11.2 1.3 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain TMEM154 PF15102.6 CBK24678.2 - 0.39 10.6 2.6 0.64 9.9 2.6 1.3 1 0 0 1 1 1 0 TMEM154 protein family RIFIN PF02009.16 CBK24678.2 - 2.1 8.2 4.6 3.3 7.5 4.6 1.2 1 0 0 1 1 1 0 Rifin FeoB_associated PF12669.7 CBK24678.2 - 4 7.9 8.2 12 6.3 8.2 1.9 1 1 0 1 1 1 0 FeoB-associated Cys-rich membrane protein Syndecan PF01034.20 CBK24678.2 - 9.5 6.2 6.7 19 5.3 6.7 1.4 1 0 0 1 1 1 0 Syndecan domain ETF PF01012.21 CBK24679.2 - 1.3e-34 119.7 0.2 1.8e-34 119.2 0.2 1.1 1 0 0 1 1 1 1 Electron transfer flavoprotein domain Acyl_transf_3 PF01757.22 CBK24680.2 - 0.24 10.4 19.8 0.008 15.3 12.3 1.9 2 0 0 2 2 2 0 Acyltransferase family DUF423 PF04241.15 CBK24680.2 - 2.2 8.5 5.4 1.2 9.4 0.3 2.9 2 1 1 4 4 4 0 Protein of unknown function (DUF423) Fun_ATP-synt_8 PF05933.13 CBK24681.2 - 3.2 8.0 8.1 3.8 7.7 5.9 2.0 2 0 0 2 2 2 0 Fungal ATP synthase protein 8 (A6L) zf-Tim10_DDP PF02953.15 CBK24682.2 - 4.1e-12 45.6 5.7 5.1e-12 45.3 5.7 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger Mito_carr PF00153.27 CBK24683.2 - 5.8e-77 253.7 3.2 1.2e-24 86.1 0.3 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 CBK24683.2 - 0.023 13.8 1.7 1.4 8.1 0.2 2.9 2 1 0 3 3 3 0 Gammaproteobacterial serine protease HAP PF03866.13 CBK24683.2 - 0.069 13.1 0.3 0.55 10.2 0.2 2.0 2 0 0 2 2 2 0 Hydrophobic abundant protein (HAP) UCR_Fe-S_N PF10399.9 CBK24683.2 - 0.49 9.8 4.9 0.14 11.5 1.6 1.7 2 0 0 2 2 2 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal Glyco_transf_92 PF01697.27 CBK24685.2 - 1.1e-15 58.0 4.3 2.9e-15 56.6 4.3 1.7 1 0 0 1 1 1 1 Glycosyltransferase family 92 Glyco_tranf_2_4 PF13704.6 CBK24685.2 - 7.4e-06 26.4 0.2 2.7e-05 24.6 0.2 1.9 1 0 0 1 1 1 1 Glycosyl transferase family 2 TatD_DNase PF01026.21 CBK24686.2 - 1.4e-46 158.9 0.0 1.7e-46 158.7 0.0 1.0 1 0 0 1 1 1 1 TatD related DNase YdjC PF04794.12 CBK24686.2 - 0.06 13.3 0.0 0.074 13.0 0.0 1.4 1 0 0 1 1 1 0 YdjC-like protein Glyco_hydro_85 PF03644.13 CBK24686.2 - 0.2 11.0 0.0 0.39 10.1 0.0 1.4 2 0 0 2 2 2 0 Glycosyl hydrolase family 85 PX PF00787.24 CBK24687.2 - 2.6e-22 78.9 0.3 4.4e-22 78.2 0.3 1.4 1 0 0 1 1 1 1 PX domain Vps5 PF09325.10 CBK24687.2 - 8.8e-09 35.3 7.9 1.6e-08 34.4 7.9 1.4 1 0 0 1 1 1 1 Vps5 C terminal like EF-hand_4 PF12763.7 CBK24687.2 - 0.0042 17.0 0.0 0.013 15.4 0.0 1.9 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand CENP-H PF05837.12 CBK24687.2 - 0.007 16.8 3.4 0.029 14.8 3.4 2.1 1 0 0 1 1 1 1 Centromere protein H (CENP-H) ATP-synt_B PF00430.18 CBK24687.2 - 0.016 15.3 11.5 0.016 15.3 11.5 2.5 3 0 0 3 3 3 0 ATP synthase B/B' CF(0) EF-hand_6 PF13405.6 CBK24687.2 - 0.028 14.3 1.2 0.093 12.7 1.2 1.9 1 0 0 1 1 1 0 EF-hand domain Golgin_A5 PF09787.9 CBK24687.2 - 0.078 12.4 3.6 0.14 11.6 3.6 1.4 1 0 0 1 1 1 0 Golgin subfamily A member 5 DUF4790 PF16037.5 CBK24687.2 - 0.1 13.1 0.9 0.7 10.4 0.0 2.7 3 0 0 3 3 2 0 Domain of unknown function (DUF4790) Mt_ATP-synt_B PF05405.14 CBK24687.2 - 0.35 10.5 3.8 1.7 8.3 3.8 2.0 1 1 0 1 1 1 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) DUF948 PF06103.11 CBK24687.2 - 1 9.7 7.0 7.4 6.9 1.3 2.6 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) DUF3813 PF12758.7 CBK24687.2 - 3.7 8.0 8.8 14 6.1 8.8 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3813) BUD22 PF09073.10 CBK24687.2 - 8.5 5.6 74.6 1.8e+04 -6.0 74.5 2.2 1 1 0 1 1 0 0 BUD22 Adap_comp_sub PF00928.21 CBK24688.2 - 1.4e-43 149.2 0.1 1.9e-43 148.8 0.1 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 CBK24688.2 - 6e-05 23.0 0.1 0.00011 22.2 0.1 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain DisA-linker PF10635.9 CBK24688.2 - 0.014 15.1 0.1 0.025 14.4 0.1 1.3 1 0 0 1 1 1 0 DisA bacterial checkpoint controller linker region Baculo_gp41 PF04700.12 CBK24688.2 - 0.12 12.1 0.1 0.19 11.5 0.1 1.3 1 0 0 1 1 1 0 Structural glycoprotein p40/gp41 conserved region Peptidase_M24 PF00557.24 CBK24689.2 - 3.7e-19 69.3 0.1 3.7e-19 69.3 0.1 1.7 2 0 0 2 2 2 1 Metallopeptidase family M24 DUF3138 PF11336.8 CBK24689.2 - 1.1 7.8 5.3 1.5 7.3 5.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) NodZ PF05830.11 CBK24690.2 - 0.055 12.3 0.0 0.095 11.5 0.0 1.3 1 0 0 1 1 1 0 Nodulation protein Z (NodZ) GP57 PF17594.2 CBK24690.2 - 0.15 11.9 0.0 0.28 11.0 0.0 1.4 1 0 0 1 1 1 0 Phage Tail fiber assembly helper gene product 57 tRNA-synt_2 PF00152.20 CBK24691.2 - 3.3e-77 259.6 0.0 4.5e-77 259.2 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 CBK24691.2 - 1.9e-13 50.2 0.1 3.8e-13 49.2 0.1 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 CBK24691.2 - 3.7e-07 29.9 0.0 0.0086 15.6 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) UCH PF00443.29 CBK24692.2 - 2.7e-21 76.2 0.0 3.4e-21 75.9 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 CBK24692.2 - 3e-06 27.1 0.0 1.5e-05 24.7 0.0 2.1 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase FKBP_N_2 PF18023.1 CBK24692.2 - 0.12 12.4 0.1 0.24 11.5 0.1 1.3 1 0 0 1 1 1 0 BDBT FKBP like N-terminal SYF2 PF08231.12 CBK24693.2 - 8.5e-25 88.0 14.1 1.2e-24 87.5 14.1 1.3 1 1 0 1 1 1 1 SYF2 splicing factor PTAC PF06130.12 CBK24693.2 - 0.085 13.0 0.1 0.13 12.5 0.1 1.2 1 0 0 1 1 1 0 Phosphate propanoyltransferase tRNA-synt_1b PF00579.25 CBK24694.2 - 7.3e-36 124.0 0.1 9.5e-36 123.6 0.1 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) Vitellogenin_N PF01347.22 CBK24694.2 - 0.012 14.1 0.2 0.014 13.8 0.2 1.2 1 0 0 1 1 1 0 Lipoprotein amino terminal region ERAP1_C PF11838.8 CBK24694.2 - 0.028 14.0 0.0 0.035 13.7 0.0 1.2 1 0 0 1 1 1 0 ERAP1-like C-terminal domain MT-A70 PF05063.14 CBK24695.2 - 2.6e-33 115.4 0.0 3.1e-33 115.1 0.0 1.0 1 0 0 1 1 1 1 MT-A70 4HBT PF03061.22 CBK24696.2 - 0.0001 22.6 0.0 0.00016 22.0 0.0 1.3 1 0 0 1 1 1 1 Thioesterase superfamily Ribophorin_II PF05817.14 CBK24700.2 - 4.9e-18 65.0 0.0 5.9e-18 64.8 0.0 1.1 1 0 0 1 1 1 1 Oligosaccharyltransferase subunit Ribophorin II RabGAP-TBC PF00566.18 CBK24701.2 - 9e-35 120.3 0.0 1.3e-34 119.8 0.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain OAD_gamma PF04277.13 CBK24702.2 - 0.077 13.6 0.0 0.077 13.6 0.0 2.1 3 0 0 3 3 3 0 Oxaloacetate decarboxylase, gamma chain DUF1385 PF07136.11 CBK24702.2 - 0.13 11.5 3.4 0.11 11.8 2.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1385) Spore_YhaL PF14147.6 CBK24702.2 - 0.14 11.9 0.5 11 5.9 0.0 2.5 2 0 0 2 2 2 0 Sporulation protein YhaL ATP-synt_8 PF00895.20 CBK24702.2 - 1.5 9.3 0.0 1.5 9.3 0.0 2.8 3 1 0 3 3 3 0 ATP synthase protein 8 ubiquitin PF00240.23 CBK24703.2 - 4.1e-17 61.7 0.4 9e-17 60.6 0.4 1.6 1 0 0 1 1 1 1 Ubiquitin family MBT PF02820.18 CBK24703.2 - 1.2e-05 25.6 0.3 3.2e-05 24.2 0.3 1.7 1 0 0 1 1 1 1 mbt repeat Rad60-SLD PF11976.8 CBK24703.2 - 5.8e-05 22.8 0.1 0.0001 22.1 0.1 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_4 PF18036.1 CBK24703.2 - 0.00017 21.6 0.2 0.2 11.7 0.0 2.9 2 1 1 3 3 3 2 Ubiquitin-like domain Tudor-knot PF11717.8 CBK24703.2 - 0.00057 19.7 1.4 0.0019 18.1 1.4 1.9 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Rad60-SLD_2 PF13881.6 CBK24703.2 - 0.0035 17.4 0.0 0.013 15.6 0.0 1.9 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Tudor_4 PF18358.1 CBK24703.2 - 0.0072 15.9 0.6 0.015 14.9 0.6 1.6 1 0 0 1 1 1 1 Histone methyltransferase Tudor domain Ubiquitin_2 PF14560.6 CBK24703.2 - 0.022 15.2 0.1 0.047 14.1 0.1 1.6 1 0 0 1 1 1 0 Ubiquitin-like domain DUF2407 PF10302.9 CBK24703.2 - 0.079 13.5 0.1 0.15 12.6 0.1 1.4 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain Metallophos PF00149.28 CBK24704.2 - 1.5e-37 130.1 0.1 1.9e-37 129.8 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 CBK24704.2 - 0.035 14.6 0.2 0.035 14.6 0.2 1.7 2 0 0 2 2 2 0 Serine-threonine protein phosphatase N-terminal domain zf-RRN7 PF11781.8 CBK24704.2 - 0.15 11.8 3.1 1.2 8.9 0.1 2.9 2 0 0 2 2 2 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 Mst1_SARAH PF11629.8 CBK24705.2 - 0.11 12.6 0.9 0.31 11.2 0.9 1.7 1 0 0 1 1 1 0 C terminal SARAH domain of Mst1 DUF3367 PF11847.8 CBK24705.2 - 1.3 6.8 3.8 1.5 6.6 3.8 1.1 1 0 0 1 1 1 0 Alpha-(1->3)-arabinofuranosyltransferase DUF4639 PF15479.6 CBK24705.2 - 2.2 7.1 17.3 2.7 6.8 17.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4639) XRN_M PF17846.1 CBK24705.2 - 2.5 6.9 12.7 3.7 6.4 12.7 1.4 1 0 0 1 1 1 0 Xrn1 helical domain Hid1 PF12722.7 CBK24705.2 - 4.6 5.3 22.9 4.8 5.2 22.9 1.3 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein SDA1 PF05285.12 CBK24705.2 - 5 6.5 43.1 8.2 5.7 43.1 1.4 1 1 0 1 1 1 0 SDA1 S4 PF01479.25 CBK24706.2 - 1.8e-12 46.8 0.4 1.8e-12 46.8 0.4 2.2 2 0 0 2 2 2 1 S4 domain zf-DBF PF07535.12 CBK24706.2 - 0.11 12.6 0.0 0.26 11.4 0.0 1.6 1 0 0 1 1 1 0 DBF zinc finger Phospholip_B PF04916.13 CBK24707.2 - 3e-144 481.5 1.2 3.7e-144 481.2 1.2 1.0 1 0 0 1 1 1 1 Phospholipase B Pkinase PF00069.25 CBK24708.2 - 1.4e-68 231.1 0.6 2.7e-68 230.2 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Not3 PF04065.15 CBK24708.2 - 3.8e-42 144.3 28.3 6.9e-42 143.5 28.3 1.3 1 0 0 1 1 1 1 Not1 N-terminal domain, CCR4-Not complex component Pkinase_Tyr PF07714.17 CBK24708.2 - 1e-41 143.0 0.0 2.2e-41 141.8 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase DUF724 PF05266.14 CBK24708.2 - 0.00036 20.4 21.6 0.011 15.6 6.8 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF724) Snapin_Pallidin PF14712.6 CBK24708.2 - 0.0049 17.3 6.7 0.0049 17.3 6.7 2.6 2 0 0 2 2 2 1 Snapin/Pallidin DUF1664 PF07889.12 CBK24708.2 - 0.0064 16.5 16.5 0.071 13.2 2.8 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF1664) DUF2203 PF09969.9 CBK24708.2 - 0.0072 17.0 12.7 0.063 14.0 2.2 2.8 1 1 1 2 2 2 2 Uncharacterized conserved protein (DUF2203) Baculo_PEP_C PF04513.12 CBK24708.2 - 0.0092 16.0 1.7 0.19 11.8 0.3 2.2 2 0 0 2 2 2 1 Baculovirus polyhedron envelope protein, PEP, C terminus SHE3 PF17078.5 CBK24708.2 - 0.012 15.4 24.2 0.34 10.6 8.5 2.5 2 0 0 2 2 2 0 SWI5-dependent HO expression protein 3 DUF4407 PF14362.6 CBK24708.2 - 0.023 14.1 16.6 0.039 13.3 16.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) YlqD PF11068.8 CBK24708.2 - 0.098 13.0 27.6 0.3 11.5 9.4 2.5 1 1 1 2 2 2 0 YlqD protein YrbL-PhoP_reg PF10707.9 CBK24708.2 - 0.12 11.9 0.1 0.12 11.9 0.1 3.2 3 1 0 3 3 3 0 PhoP regulatory network protein YrbL DUF948 PF06103.11 CBK24708.2 - 0.68 10.2 3.5 0.64 10.3 0.2 2.3 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Fib_alpha PF08702.10 CBK24708.2 - 1 9.6 23.3 2.4 8.3 6.9 2.5 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family FH2 PF02181.23 CBK24708.2 - 1.2 8.2 18.1 2.6 7.1 6.5 2.2 2 0 0 2 2 2 0 Formin Homology 2 Domain FlxA PF14282.6 CBK24708.2 - 1.3 9.1 33.6 14 5.8 19.6 2.7 1 1 1 2 2 2 0 FlxA-like protein DUF4349 PF14257.6 CBK24708.2 - 1.3 8.4 8.0 0.57 9.6 4.0 2.1 1 1 0 2 2 2 0 Domain of unknown function (DUF4349) NPV_P10 PF05531.12 CBK24708.2 - 2.1 8.9 9.3 1.2 9.6 0.1 3.1 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein DUF4549 PF15082.6 CBK24708.2 - 2.7 7.8 16.0 0.34 10.7 2.8 3.6 1 1 2 3 3 3 0 Domain of unknown function (DUF4549) Cob_adeno_trans PF01923.18 CBK24708.2 - 3.3 7.8 9.1 7 6.8 2.4 2.6 2 1 1 3 3 2 0 Cobalamin adenosyltransferase DUF3584 PF12128.8 CBK24708.2 - 3.9 4.9 24.2 5.9 4.3 24.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF4164 PF13747.6 CBK24708.2 - 6.6 7.1 11.8 11 6.4 2.8 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4164) RRF_GI PF12614.8 CBK24708.2 - 8.7 6.5 11.1 15 5.7 1.3 2.6 2 0 0 2 2 2 0 Ribosome recycling factor Neur_chan_memb PF02932.16 CBK24708.2 - 8.8 6.3 6.6 17 5.3 6.6 1.5 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region PAP_central PF04928.17 CBK24709.2 - 6.5e-24 84.3 0.0 9.1e-24 83.8 0.0 1.1 1 0 0 1 1 1 1 Poly(A) polymerase central domain PAP_RNA-bind PF04926.15 CBK24709.2 - 3.2e-12 46.4 4.3 1.4e-07 31.3 0.1 2.8 2 1 1 3 3 3 2 Poly(A) polymerase predicted RNA binding domain DUF4576 PF15144.6 CBK24709.2 - 0.14 12.0 0.0 0.53 10.2 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4576) EMP70 PF02990.16 CBK24710.2 - 9.7e-91 305.0 25.8 9.7e-91 305.0 25.8 1.4 2 0 0 2 2 2 1 Endomembrane protein 70 DUF2254 PF10011.9 CBK24710.2 - 0.4 9.5 1.9 0.97 8.2 1.9 1.6 1 0 0 1 1 1 0 Predicted membrane protein (DUF2254) EMP70 PF02990.16 CBK24711.2 - 6.2e-15 54.9 0.0 7.2e-15 54.6 0.0 1.0 1 0 0 1 1 1 1 Endomembrane protein 70 DUF563 PF04577.14 CBK24712.2 - 2.4e-22 80.1 0.2 7.1e-22 78.6 0.2 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF563) TAFII55_N PF04658.13 CBK24713.2 - 3.1e-15 56.3 0.0 1.2e-14 54.4 0.0 2.0 1 1 0 1 1 1 1 TAFII55 protein conserved region Cyclin PF08613.11 CBK24714.2 - 3.6e-23 82.7 1.2 4.5e-23 82.4 1.2 1.1 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 CBK24714.2 - 1.2e-10 41.2 0.6 1.6e-10 40.8 0.6 1.2 1 0 0 1 1 1 1 Cyclin, N-terminal domain CAP_C PF08603.11 CBK24716.2 - 7.1e-51 171.9 9.7 1e-50 171.4 9.7 1.2 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal CAP_N PF01213.19 CBK24716.2 - 1.7e-44 152.6 2.6 2.4e-44 152.1 2.6 1.1 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) N terminal TBCC PF07986.12 CBK24716.2 - 0.0014 18.4 5.7 0.0037 17.0 5.7 1.8 1 0 0 1 1 1 1 Tubulin binding cofactor C NUDIX PF00293.28 CBK24717.2 - 6.9e-17 61.7 0.1 8.4e-17 61.5 0.1 1.1 1 0 0 1 1 1 1 NUDIX domain Glucosamine_iso PF01182.20 CBK24718.2 - 3e-17 63.2 0.0 1.1e-16 61.4 0.0 1.7 1 1 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase Peptidase_M22 PF00814.25 CBK24720.2 - 1.9e-49 168.8 0.0 2.6e-49 168.4 0.0 1.1 1 0 0 1 1 1 1 Glycoprotease family Na_Ca_ex PF01699.24 CBK24721.2 - 6.9e-19 68.3 17.0 1e-18 67.7 16.9 1.3 1 1 0 1 1 1 1 Sodium/calcium exchanger protein TMEM208_SND2 PF05620.11 CBK24721.2 - 0.14 12.0 0.1 0.14 12.0 0.1 2.0 2 0 0 2 2 2 0 SRP-independent targeting protein 2/TMEM208 Flp1_like PF16982.5 CBK24721.2 - 0.4 10.1 7.3 0.12 11.8 1.9 2.5 1 1 0 2 2 2 0 Putative Flagellin, Flp1-like, domain DUF4519 PF15012.6 CBK24721.2 - 0.57 10.4 0.1 0.57 10.4 0.1 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4519) Na_Ca_ex PF01699.24 CBK24722.2 - 5.3e-21 75.2 13.3 5.3e-21 75.2 13.3 2.1 1 1 1 2 2 2 1 Sodium/calcium exchanger protein DUF2755 PF10954.8 CBK24722.2 - 0.76 9.7 3.7 2.2 8.2 3.7 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2755) DUF3432 PF11914.8 CBK24722.2 - 0.83 9.9 8.8 0.4 10.9 6.7 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3432) BES1_N PF05687.13 CBK24722.2 - 3.2 8.1 4.6 5.6 7.3 4.6 1.5 1 0 0 1 1 1 0 BES1/BZR1 plant transcription factor, N-terminal Ras PF00071.22 CBK24723.2 - 1.2e-54 184.3 0.3 1.7e-54 183.8 0.3 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CBK24723.2 - 3e-30 104.9 0.0 6e-30 103.9 0.0 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CBK24723.2 - 3.7e-14 52.6 0.0 5.4e-14 52.0 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 CBK24723.2 - 2.5e-07 30.8 0.0 1.9e-06 27.9 0.0 2.1 2 0 0 2 2 2 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 CBK24723.2 - 0.00034 20.0 0.0 0.0006 19.2 0.0 1.4 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 CBK24723.2 - 0.0017 17.9 0.1 0.014 14.9 0.0 2.1 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain DCX PF03607.17 CBK24723.2 - 0.0026 17.8 0.0 0.0057 16.7 0.0 1.6 1 0 0 1 1 1 1 Doublecortin KHA PF11834.8 CBK24723.2 - 0.0081 16.2 0.0 0.015 15.4 0.0 1.4 1 0 0 1 1 1 1 KHA, dimerisation domain of potassium ion channel FeoB_N PF02421.18 CBK24723.2 - 0.023 14.2 0.1 0.17 11.4 0.1 2.2 2 1 0 2 2 2 0 Ferrous iron transport protein B SRP19 PF01922.17 CBK24724.2 - 6.6e-27 94.3 0.0 8.7e-27 93.9 0.0 1.2 1 0 0 1 1 1 1 SRP19 protein GRDP-like PF07173.12 CBK24725.2 - 0.018 15.7 0.3 0.036 14.7 0.2 1.5 1 1 0 1 1 1 0 Glycine-rich domain-containing protein-like DHDPS PF00701.22 CBK24725.2 - 0.069 11.8 0.0 0.1 11.3 0.0 1.2 1 0 0 1 1 1 0 Dihydrodipicolinate synthetase family Sec1 PF00995.23 CBK24726.2 - 4.8e-81 273.7 0.0 5.4e-81 273.6 0.0 1.0 1 0 0 1 1 1 1 Sec1 family FSIP1 PF15554.6 CBK24726.2 - 0.011 14.9 0.0 0.022 13.8 0.0 1.4 1 0 0 1 1 1 0 FSIP1 family Evr1_Alr PF04777.13 CBK24728.2 - 3.1e-26 91.8 1.9 3.1e-26 91.8 1.9 1.7 2 0 0 2 2 2 1 Erv1 / Alr family LmjF365940-deam PF14421.6 CBK24728.2 - 0.047 13.3 0.0 0.081 12.5 0.0 1.4 1 1 0 1 1 1 0 A distinct subfamily of CDD/CDA-like deaminases Fe-ADH PF00465.19 CBK24729.2 - 5e-82 275.6 0.1 5.7e-82 275.4 0.1 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.6 CBK24729.2 - 2.7e-07 30.5 0.1 0.00064 19.5 0.0 2.2 2 0 0 2 2 2 2 Iron-containing alcohol dehydrogenase E1-E2_ATPase PF00122.20 CBK24730.2 - 6.9e-51 172.3 2.3 1.2e-49 168.3 0.9 2.5 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 CBK24730.2 - 1.9e-39 135.2 2.3 3.2e-21 75.8 0.0 3.6 4 0 0 4 4 4 2 Cation transporting ATPase, C-terminus Cation_ATPase PF13246.6 CBK24730.2 - 1.2e-21 76.6 0.0 3.5e-21 75.1 0.0 1.9 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 CBK24730.2 - 4e-18 66.5 0.0 3.9e-09 37.1 0.0 3.6 3 1 0 3 3 3 2 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 CBK24730.2 - 6.6e-16 57.8 0.0 1.4e-15 56.7 0.0 1.5 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 CBK24730.2 - 0.002 17.9 1.1 0.03 14.0 0.7 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 CBK24730.2 - 0.035 14.5 0.0 0.45 10.9 0.0 2.5 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase DUF2518 PF10726.9 CBK24730.2 - 0.095 12.4 0.8 0.25 11.0 0.8 1.7 1 0 0 1 1 1 0 Protein of function (DUF2518) Peptidase_U4 PF03419.13 CBK24730.2 - 0.27 10.5 4.6 0.1 11.9 0.1 2.2 2 0 0 2 2 2 0 Sporulation factor SpoIIGA Sigma_reg_N PF13800.6 CBK24730.2 - 0.49 10.7 9.6 1 9.7 0.1 3.0 2 0 0 2 2 2 0 Sigma factor regulator N-terminal Snf7 PF03357.21 CBK24731.2 - 3.4e-22 78.8 21.6 4.4e-22 78.5 21.6 1.0 1 0 0 1 1 1 1 Snf7 HALZ PF02183.18 CBK24731.2 - 0.0036 17.5 2.4 0.011 15.9 0.0 2.7 3 0 0 3 3 2 1 Homeobox associated leucine zipper Sec34 PF04136.15 CBK24731.2 - 0.0078 16.1 7.9 0.01 15.7 1.0 2.3 1 1 1 2 2 2 1 Sec34-like family APG6_N PF17675.1 CBK24731.2 - 0.016 15.8 4.1 0.14 12.7 0.3 2.3 2 0 0 2 2 2 0 Apg6 coiled-coil region Fmp27_WPPW PF10359.9 CBK24731.2 - 0.019 13.8 9.9 0.017 14.0 6.9 1.8 1 1 1 2 2 2 0 RNA pol II promoter Fmp27 protein domain NPV_P10 PF05531.12 CBK24731.2 - 0.073 13.5 6.5 3.3 8.2 0.6 2.6 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein Syntaxin-6_N PF09177.11 CBK24731.2 - 0.082 13.5 3.7 1.6 9.3 0.4 2.2 2 0 0 2 2 2 0 Syntaxin 6, N-terminal COG2 PF06148.11 CBK24731.2 - 0.096 12.8 10.6 0.071 13.2 2.6 2.6 1 1 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 HsbA PF12296.8 CBK24731.2 - 0.18 12.3 2.4 0.34 11.3 2.4 1.5 1 0 0 1 1 1 0 Hydrophobic surface binding protein A Ribosomal_L29 PF00831.23 CBK24731.2 - 0.19 11.8 4.7 0.28 11.2 0.2 2.8 2 1 1 3 3 3 0 Ribosomal L29 protein ABC_tran_CTD PF16326.5 CBK24731.2 - 0.32 11.3 7.4 0.13 12.5 0.6 2.7 2 1 0 2 2 2 0 ABC transporter C-terminal domain ECM11 PF15463.6 CBK24731.2 - 0.37 11.4 9.3 1 9.9 0.2 3.1 2 1 1 3 3 3 0 Extracellular mutant protein 11 Tropomyosin_1 PF12718.7 CBK24731.2 - 0.54 10.4 11.0 1.3 9.2 1.3 2.2 1 1 0 2 2 2 0 Tropomyosin like Tex_N PF09371.10 CBK24731.2 - 0.77 9.4 5.7 4.1 7.0 0.1 2.8 2 1 1 3 3 3 0 Tex-like protein N-terminal domain ADIP PF11559.8 CBK24731.2 - 0.81 9.8 9.2 0.13 12.3 4.2 2.0 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding CENP-H PF05837.12 CBK24731.2 - 1.1 9.7 9.6 8.3 6.9 6.8 2.2 2 0 0 2 2 2 0 Centromere protein H (CENP-H) Occludin_ELL PF07303.13 CBK24731.2 - 1.3 9.8 8.3 1.8 9.4 0.5 2.8 1 1 2 3 3 3 0 Occludin homology domain Nup54 PF13874.6 CBK24731.2 - 1.4 9.0 8.2 8.2 6.5 8.2 2.2 1 1 0 1 1 1 0 Nucleoporin complex subunit 54 Noelin-1 PF12308.8 CBK24731.2 - 1.6 8.8 12.0 0.3 11.1 0.4 2.8 1 1 2 3 3 3 0 Neurogenesis glycoprotein Baculo_PEP_C PF04513.12 CBK24731.2 - 2.2 8.3 8.3 2.4 8.2 3.4 2.3 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus IFT57 PF10498.9 CBK24731.2 - 2.5 7.0 15.2 0.25 10.3 6.5 2.1 1 1 1 2 2 2 0 Intra-flagellar transport protein 57 Laminin_II PF06009.12 CBK24731.2 - 2.6 8.1 7.6 1.2 9.2 2.1 2.4 1 1 1 2 2 2 0 Laminin Domain II V-ATPase_C PF03223.15 CBK24731.2 - 4.4 6.6 11.6 5.6 6.3 1.7 2.0 1 1 1 2 2 2 0 V-ATPase subunit C YabA PF06156.13 CBK24731.2 - 6.7 7.4 12.6 17 6.2 4.8 2.6 1 1 2 3 3 3 0 Initiation control protein YabA FapA PF03961.13 CBK24731.2 - 8.9 4.8 10.3 7.8 5.0 6.4 1.9 1 1 1 2 2 2 0 Flagellar Assembly Protein A Beta_helix PF13229.6 CBK24732.2 - 2.3e-08 34.0 12.7 8.2e-06 25.8 10.9 2.4 1 1 2 3 3 3 3 Right handed beta helix region PAN_4 PF14295.6 CBK24732.2 - 9e-05 22.3 0.4 0.00023 21.0 0.4 1.6 1 0 0 1 1 1 1 PAN domain PAN_1 PF00024.26 CBK24732.2 - 0.00015 21.6 0.1 0.00035 20.5 0.1 1.5 1 0 0 1 1 1 1 PAN domain DUF1565 PF07602.11 CBK24732.2 - 0.0018 17.7 2.8 0.052 12.9 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF1565) NosD PF05048.13 CBK24732.2 - 0.014 14.6 7.3 0.038 13.3 7.2 1.6 1 1 0 1 1 1 0 Periplasmic copper-binding protein (NosD) Cyclin_N2 PF16500.5 CBK24732.2 - 0.19 12.5 0.0 3.5 8.4 0.0 2.2 2 0 0 2 2 2 0 N-terminal region of cyclin_N ABC_tran PF00005.27 CBK24733.2 - 0.0017 18.9 0.0 0.002 18.6 0.0 1.2 1 0 0 1 1 1 1 ABC transporter DUF563 PF04577.14 CBK24734.2 - 9.9e-22 78.1 0.3 4.5e-21 76.0 0.3 1.9 1 1 1 2 2 2 1 Protein of unknown function (DUF563) Rhomboid PF01694.22 CBK24735.2 - 1.3e-09 38.2 8.4 1.3e-09 38.2 8.4 3.2 3 1 0 3 3 3 1 Rhomboid family DUF4014 PF13198.6 CBK24735.2 - 0.27 11.6 10.6 2.5 8.6 0.3 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF4014) LIM PF00412.22 CBK24736.2 - 1.2e-24 86.2 23.8 4.9e-14 52.3 7.8 2.6 2 0 0 2 2 2 2 LIM domain CH PF00307.31 CBK24736.2 - 9.4e-15 54.7 0.0 1.6e-14 54.0 0.0 1.4 1 0 0 1 1 1 1 Calponin homology (CH) domain ubiquitin PF00240.23 CBK24736.2 - 0.037 13.8 0.0 0.065 13.0 0.0 1.3 1 0 0 1 1 1 0 Ubiquitin family GlcNAc-1_reg PF18440.1 CBK24736.2 - 0.074 13.3 0.0 0.16 12.3 0.0 1.5 1 0 0 1 1 1 0 Putative GlcNAc-1 phosphotransferase regulatory domain Tudor-knot PF11717.8 CBK24736.2 - 0.099 12.5 0.3 0.22 11.4 0.3 1.6 1 0 0 1 1 1 0 RNA binding activity-knot of a chromodomain Pellino PF04710.14 CBK24736.2 - 0.55 8.8 6.5 3.5 6.2 0.9 2.2 2 0 0 2 2 2 0 Pellino Zn-ribbon_8 PF09723.10 CBK24736.2 - 0.71 10.0 21.9 11 6.2 0.1 5.0 4 1 0 4 4 4 0 Zinc ribbon domain DUF2175 PF09943.9 CBK24736.2 - 5.5 7.4 12.9 3.1 8.1 0.7 3.7 2 2 1 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2175) DZR PF12773.7 CBK24736.2 - 6.1 7.0 25.8 3 8.0 3.0 4.3 1 1 1 2 2 2 0 Double zinc ribbon Proteasome PF00227.26 CBK24737.2 - 9.6e-52 175.2 0.1 1.3e-51 174.9 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 CBK24737.2 - 4.8e-12 45.3 0.0 1e-11 44.3 0.0 1.6 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Yae1_N PF09811.9 CBK24737.2 - 0.00013 21.6 14.3 0.04 13.6 14.3 2.4 1 1 0 1 1 1 1 Essential protein Yae1, N terminal DUF483 PF04467.12 CBK24737.2 - 0.088 12.8 0.0 0.14 12.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF483) DUF5097 PF17020.5 CBK24737.2 - 0.14 12.5 0.0 0.3 11.4 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5097) RPEL PF02755.15 CBK24738.2 - 0.00036 20.1 4.9 0.0037 16.9 0.5 3.6 3 0 0 3 3 3 1 RPEL repeat CFAP91 PF14738.6 CBK24738.2 - 6 6.9 9.3 1.1 9.3 0.2 2.9 1 1 2 3 3 3 0 Cilia- and flagella-associated protein 91 FPL PF09758.9 CBK24739.2 - 2e-52 177.1 8.8 2e-52 177.1 8.8 2.0 2 1 0 2 2 2 1 Uncharacterised conserved protein RAI16-like PF10257.9 CBK24739.2 - 4.7e-05 22.4 5.4 0.00027 19.9 1.6 2.4 1 1 1 2 2 2 2 Retinoic acid induced 16-like protein RIX1 PF08167.12 CBK24739.2 - 0.016 15.0 0.9 0.034 13.9 0.9 1.5 1 0 0 1 1 1 0 rRNA processing/ribosome biogenesis SMG1 PF15785.5 CBK24739.2 - 0.068 11.5 4.2 0.039 12.4 2.0 1.6 1 1 0 1 1 1 0 Serine/threonine-protein kinase smg-1 HEAT PF02985.22 CBK24740.2 - 3.3e-08 33.1 4.3 0.32 11.4 0.0 5.7 5 0 0 5 5 5 1 HEAT repeat HEAT_EZ PF13513.6 CBK24740.2 - 1.2e-06 28.9 2.5 0.82 10.2 0.2 4.5 3 1 1 4 4 4 3 HEAT-like repeat CLASP_N PF12348.8 CBK24740.2 - 5.8e-06 26.0 0.3 0.00062 19.4 0.1 2.8 2 1 0 3 3 3 1 CLASP N terminal HEAT_2 PF13646.6 CBK24740.2 - 0.00074 19.9 1.1 7.4 7.0 0.1 4.4 3 1 1 4 4 4 1 HEAT repeats Cnd1 PF12717.7 CBK24740.2 - 0.0015 18.6 0.6 2.9 7.9 0.0 3.9 2 1 1 3 3 3 1 non-SMC mitotic condensation complex subunit 1 SEN1_N PF12726.7 CBK24740.2 - 0.018 13.3 0.0 0.031 12.5 0.0 1.3 1 0 0 1 1 1 0 SEN1 N terminal DUF3385 PF11865.8 CBK24740.2 - 0.029 14.3 0.2 0.25 11.3 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3385) EH_Signature PF15611.6 CBK24740.2 - 0.048 13.1 0.1 0.097 12.1 0.1 1.5 1 0 0 1 1 1 0 EH_Signature domain IFRD PF05004.13 CBK24740.2 - 0.12 11.5 0.4 8 5.5 0.0 2.6 3 0 0 3 3 3 0 Interferon-related developmental regulator (IFRD) DMA PF03474.14 CBK24740.2 - 0.12 12.0 0.0 0.41 10.3 0.0 1.9 1 0 0 1 1 1 0 DMRTA motif TFCD_C PF12612.8 CBK24740.2 - 0.13 12.0 0.1 3.4 7.5 0.1 2.3 2 0 0 2 2 2 0 Tubulin folding cofactor D C terminal DEAD PF00270.29 CBK24742.2 - 1.3e-36 126.0 0.0 3.2e-36 124.7 0.0 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 CBK24742.2 - 9.3e-07 29.0 0.0 1.7e-06 28.1 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SWI2_SNF2 PF18766.1 CBK24742.2 - 0.0014 18.4 0.0 0.0057 16.4 0.0 1.9 2 1 1 3 3 3 1 SWI2/SNF2 ATPase CMS1 PF14617.6 CBK24742.2 - 0.032 13.6 0.1 0.049 13.0 0.1 1.3 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit AAA_22 PF13401.6 CBK24742.2 - 0.072 13.4 0.0 0.88 9.8 0.1 2.3 2 0 0 2 2 2 0 AAA domain Tombus_P19 PF03220.13 CBK24742.2 - 0.2 11.4 0.0 0.37 10.5 0.0 1.3 1 0 0 1 1 1 0 Tombusvirus P19 core protein Tim17 PF02466.19 CBK24746.2 - 5.6e-12 46.0 2.4 7e-12 45.7 2.4 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Romo1 PF10247.9 CBK24746.2 - 0.36 11.2 7.8 2.6 8.5 0.2 3.1 2 1 1 3 3 3 0 Reactive mitochondrial oxygen species modulator 1 Ank_4 PF13637.6 CBK24747.2 - 6.7e-27 93.5 7.9 4.7e-11 43.0 0.1 3.5 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 CBK24747.2 - 8.8e-21 74.3 4.3 7.1e-14 52.2 0.7 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 CBK24747.2 - 7e-19 67.7 6.0 1.3e-06 28.6 0.0 4.2 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 CBK24747.2 - 6.8e-17 59.9 7.0 1.6e-06 28.0 0.1 4.5 4 1 0 4 4 4 4 Ankyrin repeat Ank PF00023.30 CBK24747.2 - 6.1e-16 58.1 10.8 2.8e-06 27.5 0.2 4.7 4 1 0 4 4 4 4 Ankyrin repeat MORN PF02493.20 CBK24748.2 - 0.00064 19.5 1.0 0.00064 19.5 1.0 3.4 3 0 0 3 3 3 2 MORN repeat Polbeta PF18765.1 CBK24749.2 - 2.2e-06 27.7 0.0 2.6e-06 27.4 0.0 1.2 1 0 0 1 1 1 1 Polymerase beta, Nucleotidyltransferase NTP_transf_2 PF01909.23 CBK24749.2 - 5.1e-06 26.7 0.0 5.6e-06 26.6 0.0 1.2 1 0 0 1 1 1 1 Nucleotidyltransferase domain Cpn60_TCP1 PF00118.24 CBK24750.2 - 2.6e-164 547.5 2.0 2.9e-164 547.3 2.0 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Mlh1_C PF16413.5 CBK24751.2 - 2.2e-47 161.7 4.3 9.8e-47 159.6 4.3 2.0 1 1 0 1 1 1 1 DNA mismatch repair protein Mlh1 C-terminus DNA_mis_repair PF01119.19 CBK24751.2 - 5e-18 64.9 0.1 9.9e-18 63.9 0.1 1.5 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.6 CBK24751.2 - 4.7e-08 33.0 0.1 1.1e-07 31.7 0.1 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 CBK24751.2 - 0.00053 20.5 0.1 0.0014 19.1 0.1 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Metallophos PF00149.28 CBK24752.2 - 1.2e-38 133.7 0.1 1.5e-38 133.3 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 CBK24752.2 - 3.9e-18 65.6 0.2 8.9e-18 64.5 0.2 1.6 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain Big_5 PF13205.6 CBK24753.2 - 4.2e-14 53.1 9.2 0.00014 22.6 0.0 5.1 6 0 0 6 6 6 3 Bacterial Ig-like domain Yae1_N PF09811.9 CBK24755.2 - 0.062 13.0 16.8 0.045 13.5 1.3 3.5 1 1 2 3 3 3 0 Essential protein Yae1, N terminal MFS_1 PF07690.16 CBK24756.2 - 1.1e-38 133.1 18.3 1.4e-38 132.8 18.3 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 CBK24756.2 - 5.9e-13 48.5 18.3 9.7e-13 47.8 18.3 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1_like PF12832.7 CBK24756.2 - 3e-05 23.0 6.7 0.0019 17.1 6.2 2.4 1 1 0 1 1 1 1 MFS_1 like family MFS_3 PF05977.13 CBK24756.2 - 0.0019 16.6 2.2 0.0019 16.6 2.2 2.3 2 0 0 2 2 2 1 Transmembrane secretion effector OATP PF03137.20 CBK24756.2 - 0.0021 16.4 13.3 0.0069 14.7 8.7 2.7 1 1 0 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family Cytochrom_B561 PF03188.16 CBK24756.2 - 0.77 9.9 7.8 0.081 13.1 0.9 2.8 2 1 1 3 3 3 0 Eukaryotic cytochrome b561 DnaJ PF00226.31 CBK24757.2 - 5.3e-18 64.9 0.1 1e-17 64.0 0.1 1.5 1 0 0 1 1 1 1 DnaJ domain ParA PF10609.9 CBK24758.2 - 0.0015 18.0 0.0 0.0018 17.8 0.0 1.1 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase ParA PF10609.9 CBK24759.2 - 1.8e-79 266.7 0.2 2.1e-79 266.4 0.2 1.0 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 CBK24759.2 - 3.9e-11 43.1 0.0 1.7e-10 41.1 0.0 1.9 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 CBK24759.2 - 7.9e-09 35.7 0.3 1.6e-07 31.4 0.3 2.1 1 1 0 1 1 1 1 AAA domain ArsA_ATPase PF02374.15 CBK24759.2 - 2.7e-08 33.4 0.1 8.5e-07 28.4 0.1 2.2 1 1 0 2 2 2 1 Anion-transporting ATPase MipZ PF09140.11 CBK24759.2 - 1.7e-07 30.8 0.0 3.6e-07 29.7 0.0 1.5 1 1 0 1 1 1 1 ATPase MipZ MeaB PF03308.16 CBK24759.2 - 4.1e-05 22.7 0.1 6.1e-05 22.1 0.1 1.2 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_25 PF13481.6 CBK24759.2 - 0.00059 19.5 0.0 0.00083 19.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_26 PF13500.6 CBK24759.2 - 0.0041 17.0 0.6 0.75 9.6 0.4 2.2 2 0 0 2 2 2 1 AAA domain NB-ARC PF00931.22 CBK24759.2 - 0.0053 16.0 0.1 0.008 15.4 0.1 1.2 1 0 0 1 1 1 1 NB-ARC domain CBP_BcsQ PF06564.12 CBK24759.2 - 0.011 15.3 0.1 0.087 12.3 0.1 2.0 1 1 0 1 1 1 0 Cellulose biosynthesis protein BcsQ AAA_16 PF13191.6 CBK24759.2 - 0.018 15.5 0.0 0.029 14.7 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain RsgA_GTPase PF03193.16 CBK24759.2 - 0.018 15.0 0.1 0.043 13.7 0.1 1.6 1 0 0 1 1 1 0 RsgA GTPase Fer4_NifH PF00142.18 CBK24759.2 - 0.019 14.4 0.1 0.034 13.6 0.1 1.4 1 0 0 1 1 1 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family APS_kinase PF01583.20 CBK24759.2 - 0.03 14.2 0.0 0.044 13.7 0.0 1.2 1 0 0 1 1 1 0 Adenylylsulphate kinase SRP54 PF00448.22 CBK24759.2 - 0.031 13.9 0.0 0.2 11.2 0.0 1.9 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain CLP1_P PF16575.5 CBK24759.2 - 0.034 13.9 0.0 0.05 13.4 0.0 1.5 1 1 0 1 1 1 0 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_29 PF13555.6 CBK24759.2 - 0.088 12.6 0.4 0.8 9.5 0.3 2.2 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_18 PF13238.6 CBK24759.2 - 0.11 13.1 0.2 0.24 12.0 0.2 1.8 1 1 0 1 1 1 0 AAA domain DAP3 PF10236.9 CBK24759.2 - 0.26 10.4 0.1 0.44 9.7 0.1 1.3 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 IMPDH PF00478.25 CBK24760.2 - 3.5e-132 440.6 3.4 4.1e-132 440.4 3.4 1.0 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain CBS PF00571.28 CBK24760.2 - 1.1e-12 48.2 0.3 3.7e-06 27.3 0.1 2.8 2 0 0 2 2 2 2 CBS domain NMO PF03060.15 CBK24760.2 - 3.5e-10 39.8 4.5 5.6e-08 32.6 0.5 3.0 3 1 0 3 3 3 2 Nitronate monooxygenase FMN_dh PF01070.18 CBK24760.2 - 8.8e-09 34.8 3.7 1.9e-08 33.7 3.7 1.5 1 1 0 1 1 1 1 FMN-dependent dehydrogenase His_biosynth PF00977.21 CBK24760.2 - 8e-08 32.0 1.6 7.4e-07 28.9 1.6 2.4 1 1 0 1 1 1 1 Histidine biosynthesis protein ThiG PF05690.14 CBK24760.2 - 4.4e-06 26.2 1.4 1.3e-05 24.7 0.8 2.0 1 1 1 2 2 2 1 Thiazole biosynthesis protein ThiG Aldolase PF01081.19 CBK24760.2 - 0.005 16.3 0.1 0.12 11.8 0.0 2.4 2 0 0 2 2 2 1 KDPG and KHG aldolase NanE PF04131.14 CBK24760.2 - 0.033 13.4 1.1 1.9 7.6 1.3 3.0 1 1 1 2 2 2 0 Putative N-acetylmannosamine-6-phosphate epimerase DUF561 PF04481.12 CBK24760.2 - 0.043 13.0 0.2 0.33 10.1 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF561) GDPD_2 PF13653.6 CBK24760.2 - 0.047 14.2 1.4 72 4.0 0.0 3.6 3 0 0 3 3 3 0 Glycerophosphoryl diester phosphodiesterase family Dus PF01207.17 CBK24760.2 - 0.075 12.1 2.3 1.5 7.9 0.0 2.9 3 0 0 3 3 3 0 Dihydrouridine synthase (Dus) YpsA PF06908.11 CBK24760.2 - 0.2 11.6 0.0 0.39 10.7 0.0 1.4 1 0 0 1 1 1 0 YspA SLOG family KTI12 PF08433.10 CBK24761.2 - 2.7e-11 43.4 0.4 1.1e-09 38.1 0.4 2.0 1 1 0 1 1 1 1 Chromatin associated protein KTI12 AAA_33 PF13671.6 CBK24761.2 - 2.1e-09 37.7 0.0 8e-08 32.6 0.0 2.0 1 1 0 1 1 1 1 AAA domain 6PF2K PF01591.18 CBK24761.2 - 1.6e-05 24.3 0.0 0.00029 20.2 0.0 2.0 1 1 0 1 1 1 1 6-phosphofructo-2-kinase AAA_18 PF13238.6 CBK24761.2 - 0.0002 21.9 0.0 0.00031 21.3 0.0 1.3 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.6 CBK24761.2 - 0.007 16.4 0.0 0.066 13.2 0.0 2.0 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 CBK24761.2 - 0.013 14.8 0.0 0.031 13.6 0.0 1.6 2 0 0 2 2 2 0 Zeta toxin AAA_16 PF13191.6 CBK24761.2 - 0.017 15.5 0.0 0.024 15.0 0.0 1.3 1 1 0 1 1 1 0 AAA ATPase domain AAA_28 PF13521.6 CBK24761.2 - 0.022 15.0 0.0 0.028 14.6 0.0 1.4 1 1 0 1 1 1 0 AAA domain GvpD PF07088.11 CBK24761.2 - 0.026 13.2 0.0 0.039 12.6 0.0 1.2 1 0 0 1 1 1 0 GvpD gas vesicle protein AAA_25 PF13481.6 CBK24761.2 - 0.033 13.8 0.1 0.1 12.2 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 CBK24761.2 - 0.048 13.9 0.1 0.45 10.8 0.1 2.0 1 1 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 CBK24761.2 - 0.048 14.0 0.0 0.85 10.0 0.0 2.3 2 1 0 2 2 2 0 RNA helicase CPT PF07931.12 CBK24761.2 - 0.083 12.7 0.0 3.8 7.3 0.0 2.1 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein Ploopntkinase3 PF18751.1 CBK24761.2 - 0.1 12.5 0.1 2.7 7.9 0.0 2.1 1 1 1 2 2 2 0 P-loop Nucleotide Kinase3 AAA_24 PF13479.6 CBK24761.2 - 0.2 11.4 0.0 0.29 10.8 0.0 1.3 1 1 0 1 1 1 0 AAA domain Ribosomal_L15e PF00827.17 CBK24762.2 - 2.9e-80 268.5 8.4 2.2e-79 265.6 8.4 1.9 1 1 0 1 1 1 1 Ribosomal L15 Ribosomal_L16 PF00252.18 CBK24763.2 - 6.7e-41 139.4 0.2 9.4e-41 138.9 0.2 1.2 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e Malate_DH PF12434.8 CBK24763.2 - 0.19 11.8 0.0 0.19 11.8 0.0 1.7 2 0 0 2 2 2 0 Malate dehydrogenase enzyme Ribosomal_S16 PF00886.19 CBK24764.2 - 1.3e-24 86.0 0.0 1.6e-24 85.7 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S16 Ribosomal_L24e PF01246.20 CBK24765.2 - 1.3e-33 115.0 3.0 1.3e-33 115.0 3.0 1.8 2 0 0 2 2 2 1 Ribosomal protein L24e Metaviral_G PF09595.10 CBK24765.2 - 0.079 13.0 0.2 0.15 12.1 0.2 1.5 1 0 0 1 1 1 0 Metaviral_G glycoprotein DUF2175 PF09943.9 CBK24765.2 - 0.13 12.6 0.5 0.13 12.6 0.5 2.9 2 1 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2175) COPIIcoated_ERV PF07970.12 CBK24766.2 - 1.2e-35 123.3 1.1 1.6e-35 122.9 1.1 1.1 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter DUF5544 PF17698.1 CBK24766.2 - 0.056 13.5 0.2 0.085 13.0 0.2 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5544) VPS13_C PF16909.5 CBK24767.2 - 8.1e-39 133.2 1.6 1.6e-38 132.2 1.6 1.6 1 0 0 1 1 1 1 Vacuolar-sorting-associated 13 protein C-terminal DUF4379 PF14311.6 CBK24767.2 - 0.1 13.0 0.2 0.23 11.9 0.2 1.5 1 0 0 1 1 1 0 Probable Zinc-ribbon domain Chorein_N PF12624.7 CBK24768.2 - 1.5e-14 54.1 1.6 1.6e-13 50.8 0.3 2.4 1 1 1 2 2 2 1 N-terminal region of Chorein or VPS13 VPS13 PF16908.5 CBK24768.2 - 9e-12 45.3 1.3 2.1e-11 44.1 1.3 1.7 1 1 0 1 1 1 1 Vacuolar sorting-associated protein 13, N-terminal Adaptin_N PF01602.20 CBK24769.2 - 1.2e-69 235.3 9.6 1.8e-69 234.7 9.6 1.2 1 0 0 1 1 1 1 Adaptin N terminal region Coatomer_b_Cpla PF14806.6 CBK24769.2 - 5.9e-46 155.6 0.0 1.4e-45 154.4 0.0 1.7 1 0 0 1 1 1 1 Coatomer beta subunit appendage platform Coatamer_beta_C PF07718.12 CBK24769.2 - 4.8e-40 136.7 0.7 9.4e-40 135.8 0.7 1.5 1 0 0 1 1 1 1 Coatomer beta C-terminal region Cnd1 PF12717.7 CBK24769.2 - 6.2e-07 29.6 0.3 0.00054 20.0 0.0 3.3 1 1 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 CBK24769.2 - 3.5e-06 27.3 0.2 2 8.9 0.0 4.8 4 1 1 5 5 5 2 HEAT repeats HEAT PF02985.22 CBK24769.2 - 4.2e-05 23.5 0.1 1.7 9.1 0.0 4.8 5 0 0 5 5 5 2 HEAT repeat FixG_C PF11614.8 CBK24769.2 - 0.11 12.7 0.0 0.26 11.5 0.0 1.5 1 0 0 1 1 1 0 IG-like fold at C-terminal of FixG, putative oxidoreductase NAPRTase_N PF17767.1 CBK24770.2 - 1.5e-35 122.3 0.1 4.4e-35 120.8 0.0 1.8 2 0 0 2 2 2 1 Nicotinate phosphoribosyltransferase (NAPRTase) N-terminal domain NAPRTase_C PF17956.1 CBK24770.2 - 9.8e-35 119.3 0.2 1.7e-34 118.6 0.2 1.4 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase C-terminal domain NAPRTase PF04095.16 CBK24770.2 - 1.8e-12 47.4 0.0 4.3e-12 46.2 0.0 1.5 1 1 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) family Helicase_C_2 PF13307.6 CBK24771.2 - 8.6e-57 192.0 0.0 1.1e-56 191.7 0.0 1.1 1 0 0 1 1 1 1 Helicase C-terminal domain Helicase_C PF00271.31 CBK24771.2 - 0.13 12.6 0.0 0.33 11.3 0.0 1.8 1 1 0 1 1 1 0 Helicase conserved C-terminal domain DEAD_2 PF06733.15 CBK24772.2 - 6.9e-37 126.8 2.2 1.2e-36 126.0 2.2 1.4 1 0 0 1 1 1 1 DEAD_2 ResIII PF04851.15 CBK24772.2 - 2.9e-06 27.4 0.1 0.0026 17.8 0.0 2.5 2 1 0 2 2 2 2 Type III restriction enzyme, res subunit DEAD PF00270.29 CBK24772.2 - 9.2e-06 25.5 0.2 0.001 18.9 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase SNF2_N PF00176.23 CBK24772.2 - 0.00079 18.2 0.0 0.0013 17.5 0.0 1.3 1 1 0 1 1 1 1 SNF2 family N-terminal domain PhoH PF02562.16 CBK24772.2 - 0.0013 18.2 0.0 0.23 10.9 0.0 2.2 2 0 0 2 2 2 2 PhoH-like protein T2SSE PF00437.20 CBK24772.2 - 0.026 13.6 0.0 0.054 12.5 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_7 PF12775.7 CBK24772.2 - 0.087 12.3 0.1 0.19 11.2 0.1 1.6 1 1 0 1 1 1 0 P-loop containing dynein motor region DUF2075 PF09848.9 CBK24772.2 - 0.1 11.8 0.0 0.98 8.6 0.0 2.0 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_22 PF13401.6 CBK24772.2 - 0.15 12.3 0.3 16 5.8 0.0 2.5 2 1 0 2 2 2 0 AAA domain DAGAT PF03982.13 CBK24773.2 - 2.4e-09 36.5 0.2 3.1e-09 36.2 0.2 1.2 1 0 0 1 1 1 1 Diacylglycerol acyltransferase FAM176 PF14851.6 CBK24774.2 - 0.16 11.6 15.6 0.16 11.6 1.8 2.5 2 0 0 2 2 2 0 FAM176 family AnfO_nitrog PF09582.10 CBK24774.2 - 0.2 11.0 7.9 0.046 13.1 2.6 2.0 2 0 0 2 2 2 0 Iron only nitrogenase protein AnfO (AnfO_nitrog) DUF719 PF05334.13 CBK24774.2 - 0.59 10.3 6.2 1 9.5 1.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF719) Pox_Ag35 PF03286.14 CBK24774.2 - 0.67 9.7 21.5 0.078 12.8 5.2 2.2 2 0 0 2 2 2 0 Pox virus Ag35 surface protein DUF1840 PF08895.11 CBK24774.2 - 0.7 10.2 6.4 3.4 8.0 2.9 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1840) Pinin_SDK_memA PF04696.13 CBK24774.2 - 0.86 9.7 13.3 0.32 11.0 3.9 2.3 2 0 0 2 2 2 0 pinin/SDK/memA/ protein conserved region DUF3899 PF13038.6 CBK24774.2 - 1 9.9 2.6 0.99 10.0 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3899) UPF0564 PF10595.9 CBK24774.2 - 1.5 7.8 14.1 0.017 14.2 3.5 2.0 2 0 0 2 2 2 0 Uncharacterised protein family UPF0564 DARPP-32 PF05395.12 CBK24774.2 - 2.9 8.1 14.7 3.3 7.9 2.2 2.3 2 0 0 2 2 2 0 Protein phosphatase inhibitor 1/DARPP-32 PRP1_N PF06424.12 CBK24774.2 - 3.1 8.2 15.1 1.1 9.6 6.9 2.2 2 0 0 2 2 2 0 PRP1 splicing factor, N-terminal PBP1_TM PF14812.6 CBK24774.2 - 6.5 7.2 10.6 4.7 7.6 2.2 2.5 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Zip PF02535.22 CBK24774.2 - 8 5.6 5.8 11 5.1 0.4 2.1 2 0 0 2 2 2 0 ZIP Zinc transporter DUF3352 PF11832.8 CBK24775.2 - 0.14 10.8 0.1 0.18 10.4 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3352) BSD PF03909.17 CBK24776.2 - 7.4e-05 22.7 0.4 0.00039 20.4 0.1 2.4 3 0 0 3 3 3 1 BSD domain EnY2 PF10163.9 CBK24777.2 - 0.1 13.0 0.0 0.25 11.8 0.0 1.6 1 0 0 1 1 1 0 Transcription factor e(y)2 DUF4973 PF16343.5 CBK24777.2 - 0.13 12.3 0.0 0.25 11.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4973) Metallophos PF00149.28 CBK24778.2 - 4e-25 89.5 0.1 5.1e-25 89.2 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 CBK24778.2 - 0.023 15.1 0.2 0.073 13.5 0.1 1.9 2 0 0 2 2 2 0 Serine-threonine protein phosphatase N-terminal domain Metallophos PF00149.28 CBK24779.2 - 0.0023 18.5 0.0 0.0043 17.6 0.0 1.5 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase S10_plectin PF03501.15 CBK24780.2 - 2.8e-28 97.8 0.1 3.9e-28 97.4 0.1 1.2 1 0 0 1 1 1 1 Plectin/S10 domain Condensin2nSMC PF12422.8 CBK24780.2 - 0.2 11.8 0.0 0.29 11.3 0.0 1.2 1 0 0 1 1 1 0 Condensin II non structural maintenance of chromosomes subunit Response_reg PF00072.24 CBK24781.2 - 6.1e-20 71.5 0.0 9.4e-20 70.9 0.0 1.2 1 0 0 1 1 1 1 Response regulator receiver domain HATPase_c PF02518.26 CBK24781.2 - 1.2e-14 54.7 0.0 2.2e-14 53.9 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 CBK24781.2 - 0.0046 16.8 0.0 0.0067 16.3 0.0 1.2 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Rft-1 PF04506.13 CBK24782.2 - 9.7e-136 453.5 27.1 1.1e-135 453.3 27.1 1.0 1 0 0 1 1 1 1 Rft protein MAPEG PF01124.18 CBK24782.2 - 3.9 7.4 11.7 3.2 7.7 0.6 3.0 2 1 1 3 3 3 0 MAPEG family Ribosomal_S17 PF00366.20 CBK24783.2 - 5.7e-28 96.8 0.4 9.5e-28 96.1 0.4 1.4 1 0 0 1 1 1 1 Ribosomal protein S17 Ribosomal_S17_N PF16205.5 CBK24783.2 - 3.1e-25 88.3 0.3 3.1e-25 88.3 0.3 1.6 2 0 0 2 2 2 1 Ribosomal_S17 N-terminal Sybindin PF04099.12 CBK24784.2 - 4.4e-34 117.5 0.2 5e-34 117.3 0.2 1.0 1 0 0 1 1 1 1 Sybindin-like family Sedlin_N PF04628.13 CBK24784.2 - 0.0019 18.3 0.0 0.0021 18.2 0.0 1.5 1 1 0 1 1 1 1 Sedlin, N-terminal conserved region tRNA-synt_1b PF00579.25 CBK24785.2 - 1.2e-66 225.1 0.0 1.5e-66 224.7 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) tRNA_bind PF01588.20 CBK24785.2 - 3.1e-24 84.9 0.0 6.4e-24 83.9 0.0 1.6 1 0 0 1 1 1 1 Putative tRNA binding domain Epimerase PF01370.21 CBK24786.2 - 7.2e-26 91.1 0.0 9.6e-26 90.7 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 CBK24786.2 - 3e-24 86.0 0.1 3.1e-23 82.7 0.1 2.1 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 CBK24786.2 - 1.2e-13 50.8 0.0 1.8e-13 50.2 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain 3Beta_HSD PF01073.19 CBK24786.2 - 4.7e-11 42.2 0.0 6.8e-11 41.7 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 CBK24786.2 - 2.1e-09 36.9 0.0 2.9e-08 33.2 0.0 2.5 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.12 CBK24786.2 - 3e-05 23.3 0.0 0.0002 20.6 0.0 2.2 2 1 0 2 2 2 1 Male sterility protein NAD_binding_10 PF13460.6 CBK24786.2 - 0.051 13.5 0.0 0.076 12.9 0.0 1.2 1 0 0 1 1 1 0 NAD(P)H-binding LRR_8 PF13855.6 CBK24787.2 - 0.085 12.6 1.1 0.35 10.6 1.2 2.0 2 0 0 2 2 2 0 Leucine rich repeat WD40 PF00400.32 CBK24788.2 - 1.3e-08 35.4 10.1 0.21 12.5 0.1 5.9 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBK24788.2 - 7e-07 29.5 0.1 0.0016 18.7 0.0 3.3 3 0 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain PRCC PF10253.9 CBK24788.2 - 0.032 15.0 2.3 0.044 14.6 2.3 1.2 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting PGM1_C PF18105.1 CBK24788.2 - 0.094 12.2 0.0 1.6 8.4 0.0 2.7 2 0 0 2 2 2 0 PGM1 C-terminal domain BORG_CEP PF14957.6 CBK24789.2 - 0.59 11.3 4.0 0.5 11.5 3.0 1.4 1 1 0 1 1 1 0 Cdc42 effector zf-C2H2_jaz PF12171.8 CBK24790.2 - 3.5e-08 33.5 2.4 6.5e-08 32.7 2.4 1.5 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 CBK24790.2 - 5.7e-06 26.6 0.2 7.7e-06 26.2 0.2 1.2 1 0 0 1 1 1 1 C2H2 type zinc-finger (2 copies) zf-C2H2_3rep PF18868.1 CBK24790.2 - 0.005 17.5 0.0 0.0083 16.8 0.0 1.3 1 0 0 1 1 1 1 Zinc finger C2H2-type, 3 repeats GH-E PF14410.6 CBK24790.2 - 0.03 14.7 1.2 1.3 9.4 0.1 2.2 2 0 0 2 2 2 0 HNH/ENDO VII superfamily nuclease with conserved GHE residues DUF4407 PF14362.6 CBK24790.2 - 0.04 13.3 0.5 0.044 13.1 0.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) zf-DBF PF07535.12 CBK24790.2 - 0.065 13.4 2.1 0.11 12.6 2.1 1.4 1 0 0 1 1 1 0 DBF zinc finger DUF4187 PF13821.6 CBK24790.2 - 0.089 12.6 1.6 0.2 11.5 1.6 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4187) zf-U1 PF06220.12 CBK24790.2 - 1.6 8.5 5.4 3.5 7.5 5.4 1.6 1 1 0 1 1 1 0 U1 zinc finger Pkr1 PF08636.10 CBK24791.2 - 1.7e-06 28.0 6.9 1.9e-06 27.9 6.9 1.1 1 0 0 1 1 1 1 ER protein Pkr1 SID-1_RNA_chan PF13965.6 CBK24791.2 - 0.0043 15.5 2.6 0.0044 15.5 2.6 1.0 1 0 0 1 1 1 1 dsRNA-gated channel SID-1 LSM PF01423.22 CBK24793.2 - 1.1e-14 53.8 0.5 1.3e-14 53.6 0.5 1.1 1 0 0 1 1 1 1 LSM domain LSM14 PF12701.7 CBK24793.2 - 0.052 13.7 0.1 0.11 12.6 0.1 1.6 1 1 0 1 1 1 0 Scd6-like Sm domain CwfJ_C_1 PF04677.15 CBK24794.2 - 6.8e-29 100.2 1.8 6.8e-29 100.2 1.8 1.5 2 0 0 2 2 2 1 Protein similar to CwfJ C-terminus 1 DUF4450 PF14614.6 CBK24794.2 - 0.0053 16.4 0.0 0.0078 15.8 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4450) NTase_sub_bind PF08780.11 CBK24794.2 - 0.044 13.8 2.4 0.91 9.5 0.1 2.7 2 1 0 2 2 2 0 Nucleotidyltransferase substrate binding protein like CCDC50_N PF15295.6 CBK24794.2 - 6.6 6.9 9.6 6.3 7.0 3.4 2.5 2 1 1 3 3 3 0 Coiled-coil domain-containing protein 50 N-terminus CwfJ_C_2 PF04676.14 CBK24795.2 - 8.7e-15 55.4 0.0 9.3e-15 55.3 0.0 1.0 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 2 zf-ZPR1 PF03367.13 CBK24796.2 - 1.3e-108 359.9 7.2 2.2e-55 186.9 0.3 2.5 3 0 0 3 3 3 2 ZPR1 zinc-finger domain HypA PF01155.19 CBK24796.2 - 0.051 13.6 2.7 3.4 7.7 0.1 2.6 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Ribosomal_L6e PF01159.19 CBK24796.2 - 7.6 7.1 9.9 1.6 9.3 6.1 1.8 2 0 0 2 2 2 0 Ribosomal protein L6e LRR_9 PF14580.6 CBK24797.2 - 6.7e-45 152.7 2.6 7.4e-45 152.6 2.6 1.0 1 0 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.7 CBK24797.2 - 0.00035 20.9 5.5 0.11 13.0 2.0 2.8 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CBK24797.2 - 0.008 15.9 2.9 0.032 14.0 1.4 2.6 2 1 0 2 2 2 1 Leucine rich repeat GNT-I PF03071.15 CBK24798.2 - 2.5e-88 296.7 0.1 3.1e-88 296.4 0.1 1.0 1 0 0 1 1 1 1 GNT-I family Glyco_transf_8 PF01501.20 CBK24798.2 - 3.6e-05 23.4 0.1 5.5e-05 22.9 0.1 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 8 Glyco_tranf_2_3 PF13641.6 CBK24798.2 - 0.043 13.7 0.2 0.35 10.7 0.2 2.1 1 1 0 1 1 1 0 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 CBK24798.2 - 0.099 12.4 0.5 1 9.2 0.5 2.2 1 1 0 1 1 1 0 Glycosyl transferase family 2 ATP-synt_D PF01813.17 CBK24799.2 - 1.8e-59 200.9 3.8 2.2e-59 200.6 3.8 1.1 1 0 0 1 1 1 1 ATP synthase subunit D Prefoldin PF02996.17 CBK24799.2 - 0.1 12.5 4.0 1.2 9.0 1.1 2.8 2 1 0 2 2 2 0 Prefoldin subunit Pescadillo_N PF06732.11 CBK24799.2 - 0.84 9.1 4.5 1.9 8.0 0.7 2.7 2 1 0 2 2 2 0 Pescadillo N-terminus FlgN PF05130.12 CBK24799.2 - 1.2 9.7 5.8 2 8.9 1.7 2.7 1 1 0 2 2 2 0 FlgN protein Glycos_transf_2 PF00535.26 CBK24800.2 - 0.00042 20.2 0.0 0.00046 20.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_4 PF13704.6 CBK24800.2 - 0.00069 20.1 0.0 0.0011 19.4 0.0 1.4 1 1 0 1 1 1 1 Glycosyl transferase family 2 OMPdecase PF00215.24 CBK24802.2 - 1.9e-28 99.6 0.0 3.4e-28 98.8 0.0 1.4 1 0 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family Pribosyltran PF00156.27 CBK24802.2 - 1.6e-17 63.5 0.3 3.8e-17 62.3 0.3 1.6 1 0 0 1 1 1 1 Phosphoribosyl transferase domain Nop14 PF04147.12 CBK24803.2 - 6e-110 368.9 57.7 3.8e-107 359.6 57.7 2.1 1 1 0 1 1 1 1 Nop14-like family Ribosomal_L30 PF00327.20 CBK24804.2 - 7.5e-21 73.8 1.8 1.8e-20 72.5 1.8 1.7 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e TPR_1 PF00515.28 CBK24806.2 - 4.4e-15 54.8 2.0 3.9e-07 29.6 0.0 3.6 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 CBK24806.2 - 5.1e-13 48.0 0.9 9.1e-05 22.3 0.0 3.6 3 1 0 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.6 CBK24806.2 - 5.5e-09 35.5 0.2 0.0024 17.9 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 CBK24806.2 - 2.1e-08 34.1 1.2 0.0003 20.8 0.0 2.8 2 1 1 3 3 2 2 Fis1 C-terminal tetratricopeptide repeat TPR_9 PF13371.6 CBK24806.2 - 1.1e-07 31.9 0.0 0.00016 21.8 0.0 2.2 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_6 PF13174.6 CBK24806.2 - 6.6e-06 26.4 0.0 0.12 13.1 0.0 2.9 3 0 0 3 3 2 2 Tetratricopeptide repeat TPR_17 PF13431.6 CBK24806.2 - 3.2e-05 24.0 0.2 0.033 14.6 0.0 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.6 CBK24806.2 - 5.3e-05 22.8 0.0 0.022 14.4 0.0 2.7 1 1 1 2 2 2 2 TPR repeat TPR_16 PF13432.6 CBK24806.2 - 0.00023 21.7 0.0 0.0023 18.6 0.0 2.3 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 CBK24806.2 - 0.00045 20.7 0.7 0.25 11.9 0.0 2.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 CBK24806.2 - 0.0015 18.4 0.0 0.31 11.2 0.0 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 CBK24806.2 - 0.002 18.8 0.0 0.42 11.6 0.0 2.5 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.6 CBK24806.2 - 0.0074 16.5 0.2 0.09 13.1 0.2 2.5 2 1 0 2 2 2 1 Tetratricopeptide repeat ANAPC3 PF12895.7 CBK24806.2 - 0.008 16.4 0.8 0.016 15.5 0.3 1.8 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 Coatomer_E PF04733.14 CBK24806.2 - 0.097 12.1 2.1 0.16 11.3 0.3 2.1 2 1 0 2 2 2 0 Coatomer epsilon subunit LCM PF04072.14 CBK24807.2 - 4.2e-08 33.3 0.0 6.5e-08 32.7 0.0 1.2 1 0 0 1 1 1 1 Leucine carboxyl methyltransferase Cnl2_NKP2 PF09447.10 CBK24807.2 - 0.011 15.9 0.2 3.5 7.8 0.1 2.6 3 0 0 3 3 3 0 Cnl2/NKP2 family protein Nmad2 PF18753.1 CBK24807.2 - 0.026 14.0 0.0 0.039 13.4 0.0 1.2 1 0 0 1 1 1 0 Nucleotide modification associated domain 2 AAA PF00004.29 CBK24808.2 - 4.7e-11 43.3 0.0 1e-10 42.2 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 CBK24808.2 - 5e-06 26.5 0.1 5.1e-05 23.3 0.0 2.4 1 1 1 2 2 2 1 Rad17 P-loop domain AAA_16 PF13191.6 CBK24808.2 - 9.4e-06 26.1 0.0 1.7e-05 25.3 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_33 PF13671.6 CBK24808.2 - 0.0013 18.9 0.0 0.0037 17.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.6 CBK24808.2 - 0.003 17.6 0.1 0.013 15.5 0.0 2.0 2 0 0 2 2 2 1 AAA domain RuvB_N PF05496.12 CBK24808.2 - 0.0045 16.8 0.0 0.0091 15.8 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_assoc_2 PF16193.5 CBK24808.2 - 0.0052 17.1 0.0 0.015 15.6 0.0 1.8 1 0 0 1 1 1 1 AAA C-terminal domain Sigma54_activ_2 PF14532.6 CBK24808.2 - 0.0058 16.7 0.0 0.026 14.6 0.0 2.1 2 1 0 2 2 2 1 Sigma-54 interaction domain AAA_22 PF13401.6 CBK24808.2 - 0.007 16.6 0.2 0.17 12.2 0.0 2.5 1 1 1 2 2 2 1 AAA domain RNA_helicase PF00910.22 CBK24808.2 - 0.019 15.3 0.0 0.15 12.5 0.0 2.3 1 1 0 1 1 1 0 RNA helicase TniB PF05621.11 CBK24808.2 - 0.024 14.0 0.1 2.3 7.6 0.0 2.4 1 1 1 2 2 2 0 Bacterial TniB protein ABC_tran PF00005.27 CBK24808.2 - 0.036 14.6 0.0 0.45 11.0 0.0 2.8 2 1 1 3 3 3 0 ABC transporter NTPase_1 PF03266.15 CBK24808.2 - 0.039 13.9 0.2 0.099 12.5 0.1 1.7 1 1 1 2 2 2 0 NTPase AAA_19 PF13245.6 CBK24808.2 - 0.057 13.7 0.2 0.19 12.1 0.1 2.0 2 1 0 2 2 2 0 AAA domain AAA_11 PF13086.6 CBK24808.2 - 0.081 12.7 0.0 0.081 12.7 0.0 2.3 2 0 0 2 2 2 0 AAA domain TUTF7_u4 PF16631.5 CBK24808.2 - 7.1 7.3 8.0 4.9 7.9 5.5 2.0 1 1 1 2 2 2 0 Unstructured region 4 on terminal uridylyltransferase 7 RNA_pol_Rpb2_6 PF00562.28 CBK24809.2 - 3.6e-112 375.3 0.0 5.1e-112 374.8 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 CBK24809.2 - 4.2e-42 144.0 0.2 6.6e-42 143.3 0.2 1.2 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.14 CBK24809.2 - 2.4e-22 79.5 0.0 3.9e-22 78.8 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_4 PF04566.13 CBK24809.2 - 8.1e-22 77.3 0.7 2.5e-21 75.7 0.6 2.0 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_3 PF04565.16 CBK24809.2 - 4.4e-19 68.4 0.0 8.4e-19 67.5 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_7 PF04560.20 CBK24809.2 - 3.5e-12 46.5 0.1 9.8e-12 45.1 0.1 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_5 PF04567.17 CBK24809.2 - 4.5e-10 39.9 0.7 1.5e-09 38.2 0.7 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 Sec23_trunk PF04811.15 CBK24810.2 - 1.4e-58 198.4 0.0 1.9e-58 197.9 0.0 1.2 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_BS PF08033.12 CBK24810.2 - 4.6e-26 91.4 0.2 1.4e-25 89.9 0.0 2.0 2 0 0 2 2 2 1 Sec23/Sec24 beta-sandwich domain Sec23_helical PF04815.15 CBK24810.2 - 9.3e-23 80.0 0.2 2.3e-22 78.8 0.2 1.7 1 0 0 1 1 1 1 Sec23/Sec24 helical domain zf-Sec23_Sec24 PF04810.15 CBK24810.2 - 1.9e-18 66.2 8.1 4.4e-18 65.1 8.1 1.7 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 CBK24810.2 - 9.4e-13 47.9 0.0 1.8e-12 47.0 0.0 1.5 1 0 0 1 1 1 1 Gelsolin repeat VWA_2 PF13519.6 CBK24810.2 - 0.2 12.3 0.0 3.8 8.2 0.0 2.4 1 1 0 2 2 2 0 von Willebrand factor type A domain tRNA-synt_1e PF01406.19 CBK24811.2 - 1.5e-116 389.0 0.3 1.5e-116 389.0 0.3 1.6 2 0 0 2 2 2 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.11 CBK24811.2 - 9.7e-14 50.9 3.4 2.2e-06 26.7 0.6 2.2 2 0 0 2 2 2 2 tRNA synthetases class I (M) tRNA-synt_1c PF00749.21 CBK24811.2 - 0.00018 20.5 0.0 0.00018 20.5 0.0 2.7 3 0 0 3 3 3 1 tRNA synthetases class I (E and Q), catalytic domain DALR_2 PF09190.11 CBK24811.2 - 0.0011 19.4 0.0 0.011 16.2 0.0 2.6 2 0 0 2 2 2 1 DALR domain tRNA-synt_1 PF00133.22 CBK24811.2 - 0.24 9.6 0.0 0.24 9.6 0.0 3.1 3 1 0 3 3 3 0 tRNA synthetases class I (I, L, M and V) ALG3 PF05208.13 CBK24812.2 - 8e-119 397.2 20.7 9.3e-119 397.0 20.7 1.0 1 0 0 1 1 1 1 ALG3 protein GFO_IDH_MocA PF01408.22 CBK24813.2 - 7.7e-14 52.6 0.1 2.1e-13 51.2 0.1 1.7 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 CBK24813.2 - 0.0043 17.1 0.0 0.0087 16.1 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain Nucleotid_trans PF03407.16 CBK24814.2 - 2.9e-17 63.4 0.0 3.9e-17 62.9 0.0 1.1 1 0 0 1 1 1 1 Nucleotide-diphospho-sugar transferase DUF4748 PF15932.5 CBK24815.2 - 0.0075 16.0 0.0 0.013 15.3 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4748) BRCT_2 PF16589.5 CBK24816.2 - 1.9e-13 50.6 0.2 1.3e-06 28.7 0.0 3.6 4 0 0 4 4 4 3 BRCT domain, a BRCA1 C-terminus domain PTCB-BRCT PF12738.7 CBK24816.2 - 5.4e-11 42.3 1.5 3.2e-05 23.8 0.1 4.5 4 0 0 4 4 4 3 twin BRCT domain LIG3_BRCT PF16759.5 CBK24816.2 - 1.1e-07 32.1 0.0 0.39 11.0 0.0 3.6 3 0 0 3 3 3 3 DNA ligase 3 BRCT domain BRCT PF00533.26 CBK24816.2 - 3.6e-05 24.1 4.3 0.01 16.2 0.4 4.8 4 2 0 4 4 4 1 BRCA1 C Terminus (BRCT) domain RTT107_BRCT_5 PF16770.5 CBK24816.2 - 0.014 15.2 0.2 5.7 6.9 0.1 3.3 3 1 0 3 3 3 0 Regulator of Ty1 transposition protein 107 BRCT domain Rcd1 PF04078.13 CBK24816.2 - 0.14 11.4 0.0 0.22 10.8 0.0 1.2 1 0 0 1 1 1 0 Cell differentiation family, Rcd1-like UDPGP PF01704.18 CBK24818.2 - 7.9e-12 44.5 0.0 1.1e-11 44.0 0.0 1.2 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase Thioredoxin_8 PF13905.6 CBK24819.2 - 6.4e-72 238.0 0.0 5.3e-25 87.6 0.0 3.7 4 0 0 4 4 4 3 Thioredoxin-like Thioredoxin PF00085.20 CBK24819.2 - 4.3e-19 68.4 0.3 4e-07 30.0 0.1 5.0 3 2 2 5 5 5 3 Thioredoxin Thioredoxin_2 PF13098.6 CBK24819.2 - 1.9e-12 47.6 0.1 0.00096 19.6 0.0 4.2 4 1 0 4 4 4 3 Thioredoxin-like domain AhpC-TSA PF00578.21 CBK24819.2 - 1.2e-10 41.3 0.0 0.00019 21.3 0.0 2.5 2 0 0 2 2 2 2 AhpC/TSA family Redoxin PF08534.10 CBK24819.2 - 1.8e-10 40.7 0.0 0.00063 19.5 0.0 2.9 3 0 0 3 3 3 2 Redoxin SCO1-SenC PF02630.14 CBK24819.2 - 4.2e-05 23.5 0.0 0.18 11.7 0.0 3.2 3 0 0 3 3 3 2 SCO1/SenC Thioredoxin_7 PF13899.6 CBK24819.2 - 0.00016 21.8 0.0 0.2 11.9 0.0 3.4 4 0 0 4 4 4 1 Thioredoxin-like Thioredoxin_6 PF13848.6 CBK24819.2 - 0.0053 16.7 0.0 0.016 15.2 0.0 1.8 2 0 0 2 2 2 1 Thioredoxin-like domain NADH_4Fe-4S PF10589.9 CBK24819.2 - 0.0082 16.2 0.0 7.3 6.7 0.0 3.1 3 0 0 3 3 3 1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region Thioredoxin_9 PF14595.6 CBK24819.2 - 0.016 15.0 0.0 3.6 7.4 0.0 3.2 4 0 0 4 4 4 0 Thioredoxin tRNA_edit PF04073.15 CBK24820.2 - 1.2e-13 51.2 0.0 1.3e-13 51.1 0.0 1.0 1 0 0 1 1 1 1 Aminoacyl-tRNA editing domain GST_C_2 PF13410.6 CBK24822.2 - 0.0053 16.8 0.0 0.0074 16.3 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 CBK24822.2 - 0.0072 16.5 0.0 0.01 16.1 0.0 1.4 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain zf-C2H2_4 PF13894.6 CBK24823.2 - 5e-06 26.9 3.1 0.081 13.8 0.5 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.26 CBK24823.2 - 4.3e-05 23.7 6.7 0.03 14.8 2.1 2.4 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_6 PF13912.6 CBK24823.2 - 0.00013 21.9 5.0 0.0029 17.6 3.9 2.4 1 1 1 2 2 2 1 C2H2-type zinc finger zf-Di19 PF05605.12 CBK24823.2 - 0.00031 21.0 3.0 0.0093 16.2 0.5 2.3 1 1 1 2 2 2 2 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_jaz PF12171.8 CBK24823.2 - 0.0014 18.8 6.7 0.0033 17.7 0.4 2.3 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 CBK24823.2 - 0.014 15.7 4.3 0.093 13.1 1.0 2.3 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) Amelogenin PF02948.15 CBK24823.2 - 0.035 14.8 22.3 0.094 13.4 22.0 1.9 1 1 0 1 1 1 0 Amelogenin CCDC84 PF14968.6 CBK24823.2 - 0.052 13.2 2.8 0.058 13.0 1.9 1.3 1 1 0 1 1 1 0 Coiled coil protein 84 PyrI_C PF02748.15 CBK24823.2 - 0.18 11.7 9.3 1.9 8.5 0.9 2.5 1 1 1 2 2 2 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-C2HE PF16278.5 CBK24823.2 - 0.37 11.3 5.3 4.8 7.7 0.7 2.7 2 1 1 3 3 3 0 C2HE / C2H2 / C2HC zinc-binding finger zf-ribbon_3 PF13248.6 CBK24823.2 - 0.47 10.0 2.5 20 4.8 0.1 2.3 2 0 0 2 2 2 0 zinc-ribbon domain zf-CHCC PF10276.9 CBK24823.2 - 0.49 10.5 4.9 4.7 7.4 0.5 2.3 2 0 0 2 2 2 0 Zinc-finger domain zf-C2HC_2 PF13913.6 CBK24823.2 - 0.7 9.9 3.0 11 6.1 0.1 2.3 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf-H2C2_2 PF13465.6 CBK24823.2 - 2.5 8.7 8.3 1.8 9.1 0.3 3.2 3 0 0 3 3 3 0 Zinc-finger double domain Forkhead_N PF08430.12 CBK24823.2 - 2.8 8.5 45.4 15 6.2 45.4 2.0 1 1 0 1 1 1 0 Forkhead N-terminal region zf-BED PF02892.15 CBK24823.2 - 4.9 7.3 6.5 92 3.2 0.1 2.3 1 1 1 2 2 2 0 BED zinc finger zf-UBP PF02148.19 CBK24823.2 - 6.7 7.1 6.4 0.57 10.6 0.8 1.9 2 0 0 2 2 2 0 Zn-finger in ubiquitin-hydrolases and other protein Ribosomal_S7 PF00177.21 CBK24824.2 - 1.2e-39 135.3 0.5 1.5e-39 135.0 0.5 1.1 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e WD40 PF00400.32 CBK24825.2 - 3.4e-05 24.5 2.2 0.013 16.3 0.1 4.3 4 0 0 4 4 4 1 WD domain, G-beta repeat HSP70 PF00012.20 CBK24826.2 - 3.4e-37 127.9 1.0 4e-34 117.8 0.0 2.8 2 1 1 3 3 3 2 Hsp70 protein MreB_Mbl PF06723.13 CBK24826.2 - 3.2e-07 29.5 0.0 2.3e-06 26.7 0.0 2.3 2 1 1 3 3 3 1 MreB/Mbl protein Cauli_DNA-bind PF03310.13 CBK24826.2 - 0.077 13.1 0.8 0.35 10.9 0.1 2.2 2 0 0 2 2 2 0 Caulimovirus DNA-binding protein Tissue_fac PF01108.17 CBK24826.2 - 0.45 10.4 1.8 0.78 9.6 0.3 2.0 2 0 0 2 2 2 0 Tissue factor Ribosomal_S9 PF00380.19 CBK24827.2 - 1.3e-29 103.2 0.1 1.4e-29 103.0 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S9/S16 AICARFT_IMPCHas PF01808.18 CBK24828.2 - 3.2e-83 279.6 0.1 4.3e-83 279.2 0.1 1.2 1 0 0 1 1 1 1 AICARFT/IMPCHase bienzyme MGS PF02142.22 CBK24828.2 - 8.7e-27 93.2 0.0 2.5e-26 91.7 0.0 1.9 1 0 0 1 1 1 1 MGS-like domain Glyco_hydro_47 PF01532.20 CBK24829.2 - 5.7e-49 167.2 0.0 7.3e-49 166.9 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Dus PF01207.17 CBK24830.2 - 9.5e-27 93.9 0.0 1.2e-26 93.6 0.0 1.1 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) DUF410 PF04190.13 CBK24831.2 - 1.4e-29 103.7 0.1 1.5e-29 103.6 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF410) Vps54_N PF10475.9 CBK24832.2 - 0.0082 15.5 0.1 0.0087 15.4 0.1 1.1 1 0 0 1 1 1 1 Vacuolar-sorting protein 54, of GARP complex MIT PF04212.18 CBK24832.2 - 0.027 14.5 1.8 0.81 9.8 0.4 2.1 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain Exo_endo_phos PF03372.23 CBK24833.2 - 9.5e-14 51.5 0.0 1.9e-13 50.5 0.0 1.5 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Met_10 PF02475.16 CBK24834.2 - 2e-64 217.0 0.0 2.6e-64 216.6 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_25 PF13649.6 CBK24834.2 - 0.0013 19.4 0.0 0.0065 17.1 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain FmrO PF07091.11 CBK24834.2 - 0.0052 16.4 0.0 0.0087 15.6 0.0 1.3 1 0 0 1 1 1 1 Ribosomal RNA methyltransferase (FmrO) Methyltransf_15 PF09445.10 CBK24834.2 - 0.014 15.0 0.1 0.025 14.2 0.1 1.4 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase MTS PF05175.14 CBK24834.2 - 0.03 13.9 0.0 0.049 13.2 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain TRM PF02005.16 CBK24834.2 - 0.073 12.2 0.0 0.12 11.5 0.0 1.2 1 0 0 1 1 1 0 N2,N2-dimethylguanosine tRNA methyltransferase tRNA_U5-meth_tr PF05958.11 CBK24834.2 - 0.075 12.0 0.0 0.11 11.4 0.0 1.2 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase Amj PF10997.8 CBK24834.2 - 0.11 11.8 0.0 0.18 11.1 0.0 1.2 1 0 0 1 1 1 0 Alternate to MurJ DUF433 PF04255.14 CBK24835.2 - 0.012 15.4 0.4 0.09 12.6 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF433) Skp1 PF01466.19 CBK24835.2 - 1 9.5 5.4 1.4 9.1 0.3 2.9 2 1 0 2 2 2 0 Skp1 family, dimerisation domain HpcH_HpaI PF03328.14 CBK24836.2 - 2.1e-47 161.1 0.0 8.3e-47 159.2 0.0 1.8 2 0 0 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family C-C_Bond_Lyase PF15617.6 CBK24836.2 - 5.2e-13 48.9 0.0 7.8e-08 31.8 0.0 2.2 2 0 0 2 2 2 2 C-C_Bond_Lyase of the TIM-Barrel fold PK PF00224.21 CBK24836.2 - 0.0036 16.2 0.1 0.0055 15.6 0.1 1.2 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PEP-utilizers_C PF02896.18 CBK24836.2 - 0.033 13.3 0.0 0.057 12.5 0.0 1.3 1 0 0 1 1 1 0 PEP-utilising enzyme, TIM barrel domain Sulfate_transp PF00916.20 CBK24837.2 - 3e-83 279.7 16.5 3.6e-83 279.4 16.5 1.0 1 0 0 1 1 1 1 Sulfate permease family DUF1282 PF06930.12 CBK24837.2 - 0.0004 20.2 1.6 0.0004 20.2 1.6 2.7 2 1 0 2 2 2 1 Protein of unknown function (DUF1282) UMP1 PF05348.11 CBK24838.2 - 3.6e-07 30.4 0.0 4.2e-07 30.2 0.0 1.1 1 0 0 1 1 1 1 Proteasome maturation factor UMP1 DEAD PF00270.29 CBK24839.2 - 4e-45 153.7 0.0 2.1e-43 148.1 0.0 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CBK24839.2 - 2.4e-27 95.4 0.0 7.3e-27 93.9 0.1 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 CBK24839.2 - 0.0021 18.1 0.0 0.018 15.1 0.0 2.5 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit DUF4652 PF15525.6 CBK24839.2 - 0.11 12.3 4.7 0.21 11.3 4.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4652) RRN3 PF05327.11 CBK24839.2 - 7.4 5.0 8.9 14 4.1 8.9 1.3 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 TatD_DNase PF01026.21 CBK24840.2 - 1.4e-49 168.8 0.0 1.9e-49 168.3 0.0 1.1 1 0 0 1 1 1 1 TatD related DNase PUB PF09409.10 CBK24841.2 - 1.4e-05 24.9 0.0 2.3e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 PUB domain Hamartin PF04388.12 CBK24841.2 - 5.4 5.6 14.3 7.5 5.1 14.3 1.3 1 0 0 1 1 1 0 Hamartin protein WD40 PF00400.32 CBK24842.2 - 3.3e-22 78.4 7.9 2.3e-06 28.2 0.1 4.1 4 0 0 4 4 4 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBK24842.2 - 2.1e-09 37.6 0.0 0.0012 19.1 0.0 3.6 1 1 2 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 CBK24842.2 - 0.011 15.6 0.4 0.052 13.5 0.2 2.2 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat Ge1_WD40 PF16529.5 CBK24842.2 - 0.016 14.2 0.7 0.68 8.8 0.0 2.7 1 1 1 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein RabGAP-TBC PF00566.18 CBK24843.2 - 0.084 12.5 3.0 0.14 11.8 3.0 1.4 1 0 0 1 1 1 0 Rab-GTPase-TBC domain Nairovirus_M PF07948.11 CBK24843.2 - 0.16 10.2 0.1 0.21 9.8 0.1 1.1 1 0 0 1 1 1 0 Nairovirus M polyprotein-like TLD PF07534.16 CBK24844.2 - 2.9e-13 50.2 0.0 4.5e-13 49.6 0.0 1.3 1 0 0 1 1 1 1 TLD Malt_amylase_C PF16657.5 CBK24845.2 - 0.0031 17.6 0.0 0.0082 16.2 0.0 1.8 1 0 0 1 1 1 1 Maltogenic Amylase, C-terminal domain Alpha-amylase_C PF02806.18 CBK24845.2 - 0.062 13.8 0.0 0.51 10.8 0.0 2.4 2 1 0 2 2 2 0 Alpha amylase, C-terminal all-beta domain Alpha-amylase PF00128.24 CBK24845.2 - 0.088 12.4 0.0 0.29 10.6 0.0 1.9 2 0 0 2 2 2 0 Alpha amylase, catalytic domain Peptidase_C1 PF00112.23 CBK24846.2 - 3.2e-63 213.8 5.7 4.7e-63 213.2 5.7 1.2 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 CBK24846.2 - 1.8e-09 37.9 0.4 2.8e-09 37.3 0.4 1.3 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) DUF3343 PF11823.8 CBK24846.2 - 0.0046 16.4 0.4 3.2 7.3 0.0 2.6 3 0 0 3 3 3 2 Protein of unknown function (DUF3343) EMP24_GP25L PF01105.24 CBK24847.2 - 1.4e-18 67.5 0.1 1.3e-16 61.1 0.1 2.0 2 0 0 2 2 2 2 emp24/gp25L/p24 family/GOLD Xpo1 PF08389.12 CBK24848.2 - 1e-11 45.1 1.5 1.7e-11 44.4 1.4 1.4 1 1 0 1 1 1 1 Exportin 1-like protein FKBP_C PF00254.28 CBK24849.2 - 5.9e-33 113.1 0.0 1.3e-32 111.9 0.0 1.6 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase CAP_N PF01213.19 CBK24850.2 - 0.068 12.7 0.5 0.1 12.1 0.5 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal RHIM PF12721.7 CBK24850.2 - 0.14 12.7 0.1 0.14 12.7 0.1 1.8 2 0 0 2 2 2 0 RIP homotypic interaction motif ADK PF00406.22 CBK24851.2 - 1.2e-36 126.1 0.0 1.5e-36 125.8 0.0 1.0 1 0 0 1 1 1 1 Adenylate kinase ADK_lid PF05191.14 CBK24851.2 - 5.9e-16 58.1 1.4 1.5e-15 56.9 1.4 1.7 1 1 0 1 1 1 1 Adenylate kinase, active site lid AAA_17 PF13207.6 CBK24851.2 - 6.9e-12 46.0 0.0 1.8e-11 44.6 0.0 1.6 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 CBK24851.2 - 0.0016 19.0 0.0 0.003 18.1 0.0 1.5 2 0 0 2 2 2 1 AAA domain zf-C2HC_2 PF13913.6 CBK24851.2 - 0.019 14.9 0.2 0.044 13.7 0.2 1.6 1 0 0 1 1 1 0 zinc-finger of a C2HC-type Mg_chelatase PF01078.21 CBK24851.2 - 0.07 12.5 0.0 0.22 10.9 0.0 1.7 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI TerY_C PF15616.6 CBK24851.2 - 0.08 13.1 0.0 0.12 12.5 0.0 1.2 1 0 0 1 1 1 0 TerY-C metal binding domain AAA_29 PF13555.6 CBK24851.2 - 0.083 12.6 0.0 0.23 11.2 0.0 1.7 2 0 0 2 2 2 0 P-loop containing region of AAA domain A2L_zn_ribbon PF08792.10 CBK24851.2 - 0.093 12.5 0.3 4.7 7.0 0.0 2.3 2 0 0 2 2 2 0 A2L zinc ribbon domain DZR PF12773.7 CBK24851.2 - 0.11 12.6 0.4 0.3 11.1 0.5 1.6 1 1 0 1 1 1 0 Double zinc ribbon AAA_33 PF13671.6 CBK24851.2 - 0.13 12.4 0.1 1.6 8.9 0.0 2.2 2 0 0 2 2 2 0 AAA domain zf-CCHC PF00098.23 CBK24852.2 - 4.4e-10 39.2 7.0 1.1e-05 25.2 0.7 7.3 7 0 0 7 7 7 4 Zinc knuckle zf-CCHC_2 PF13696.6 CBK24852.2 - 1.4e-05 24.8 7.7 0.00025 20.8 2.2 6.9 7 0 0 7 7 7 5 Zinc knuckle Ribosomal_S7 PF00177.21 CBK24853.2 - 1.2e-39 135.3 0.5 1.5e-39 135.0 0.5 1.1 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e zf-C2H2_4 PF13894.6 CBK24854.2 - 5.8e-06 26.7 3.1 0.086 13.7 0.5 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.26 CBK24854.2 - 5e-05 23.5 6.7 0.032 14.7 2.1 2.4 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_6 PF13912.6 CBK24854.2 - 0.00016 21.5 5.1 0.0028 17.6 3.8 2.4 1 1 1 2 2 2 1 C2H2-type zinc finger zf-Di19 PF05605.12 CBK24854.2 - 0.00036 20.8 3.0 0.01 16.1 0.5 2.3 1 1 1 2 2 2 2 Drought induced 19 protein (Di19), zinc-binding Amelogenin PF02948.15 CBK24854.2 - 0.0015 19.2 29.7 0.31 11.6 16.4 2.6 1 1 1 2 2 2 2 Amelogenin zf-C2H2_jaz PF12171.8 CBK24854.2 - 0.0016 18.6 6.7 0.0035 17.6 0.4 2.3 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding DUF4813 PF16072.5 CBK24854.2 - 0.0081 15.9 25.7 0.013 15.2 25.7 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4813) zf-C2H2_2 PF12756.7 CBK24854.2 - 0.016 15.5 4.3 0.1 13.0 1.0 2.3 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) CCDC84 PF14968.6 CBK24854.2 - 0.056 13.1 2.7 0.071 12.7 2.0 1.3 1 1 0 1 1 1 0 Coiled coil protein 84 PyrI_C PF02748.15 CBK24854.2 - 0.2 11.6 9.3 2 8.4 0.9 2.5 1 1 1 2 2 2 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-C2HE PF16278.5 CBK24854.2 - 0.43 11.1 5.3 5.1 7.6 0.7 2.7 2 1 1 3 3 3 0 C2HE / C2H2 / C2HC zinc-binding finger zf-ribbon_3 PF13248.6 CBK24854.2 - 0.52 9.8 2.5 21 4.7 0.1 2.3 2 0 0 2 2 2 0 zinc-ribbon domain zf-CHCC PF10276.9 CBK24854.2 - 0.56 10.3 4.9 4.9 7.3 0.5 2.3 2 0 0 2 2 2 0 Zinc-finger domain zf-C2HC_2 PF13913.6 CBK24854.2 - 0.79 9.7 3.0 11 6.0 0.1 2.3 2 0 0 2 2 2 0 zinc-finger of a C2HC-type Forkhead_N PF08430.12 CBK24854.2 - 0.83 10.3 54.8 11 6.7 54.8 2.3 1 1 0 1 1 1 0 Forkhead N-terminal region zf-H2C2_2 PF13465.6 CBK24854.2 - 3 8.4 8.3 2 9.0 0.3 3.2 3 0 0 3 3 3 0 Zinc-finger double domain zf-BED PF02892.15 CBK24854.2 - 6.9 6.8 6.7 1.9e+02 2.1 6.8 2.3 1 1 0 1 1 1 0 BED zinc finger GST_C_2 PF13410.6 CBK24855.2 - 0.0053 16.8 0.0 0.0074 16.3 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 CBK24855.2 - 0.0072 16.5 0.0 0.01 16.1 0.0 1.4 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain tRNA_edit PF04073.15 CBK24857.2 - 1.2e-13 51.2 0.0 1.3e-13 51.1 0.0 1.0 1 0 0 1 1 1 1 Aminoacyl-tRNA editing domain Thioredoxin_8 PF13905.6 CBK24858.2 - 1.1e-28 99.3 0.0 1.4e-28 99.0 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin PF00085.20 CBK24858.2 - 1.8e-08 34.3 0.0 2.7e-05 24.1 0.0 2.1 1 1 1 2 2 2 2 Thioredoxin Redoxin PF08534.10 CBK24858.2 - 1.8e-07 31.0 0.0 2.4e-07 30.6 0.0 1.1 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 CBK24858.2 - 6.6e-07 29.3 0.0 7.8e-07 29.1 0.0 1.2 1 1 0 1 1 1 1 AhpC/TSA family Thioredoxin_2 PF13098.6 CBK24858.2 - 8.2e-06 26.2 0.0 1.3e-05 25.6 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like domain SCO1-SenC PF02630.14 CBK24858.2 - 0.004 17.1 0.0 0.0061 16.5 0.0 1.2 1 0 0 1 1 1 1 SCO1/SenC Thioredoxin_7 PF13899.6 CBK24858.2 - 0.012 15.7 0.0 0.027 14.6 0.0 1.6 1 1 0 1 1 1 0 Thioredoxin-like Kinesin PF00225.23 CBK24859.2 - 8.3e-96 320.8 2.2 9.8e-96 320.6 2.2 1.0 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 CBK24859.2 - 4.8e-51 172.6 0.1 9.6e-51 171.6 0.1 1.5 1 0 0 1 1 1 1 Microtubule binding DHQ_synthase PF01761.20 CBK24860.2 - 0.034 13.3 0.0 0.04 13.1 0.0 1.2 1 0 0 1 1 1 0 3-dehydroquinate synthase Fe-ADH PF00465.19 CBK24860.2 - 0.073 11.9 0.0 0.082 11.7 0.0 1.1 1 0 0 1 1 1 0 Iron-containing alcohol dehydrogenase HAUS-augmin3 PF14932.6 CBK24860.2 - 0.076 12.6 0.0 0.084 12.4 0.0 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 Fe-ADH PF00465.19 CBK24861.2 - 1.2e-36 126.4 0.1 1.4e-36 126.1 0.1 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.6 CBK24861.2 - 2.3e-25 89.8 0.0 2.7e-25 89.5 0.0 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase DHQ_synthase PF01761.20 CBK24861.2 - 2.7e-05 23.5 0.1 4.6e-05 22.7 0.1 1.4 1 1 0 1 1 1 1 3-dehydroquinate synthase AIRC PF00731.20 CBK24861.2 - 0.0024 17.4 0.0 0.007 15.9 0.0 1.8 2 0 0 2 2 2 1 AIR carboxylase Rad10 PF03834.14 CBK24862.2 - 4.6e-10 39.5 0.1 9.2e-10 38.5 0.0 1.6 2 0 0 2 2 2 1 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) HHH_5 PF14520.6 CBK24862.2 - 9.1e-07 29.4 0.0 1.6e-06 28.6 0.0 1.4 1 0 0 1 1 1 1 Helix-hairpin-helix domain HHH_2 PF12826.7 CBK24862.2 - 0.00018 21.5 0.0 0.00038 20.5 0.0 1.5 1 0 0 1 1 1 1 Helix-hairpin-helix motif HSBP1 PF06825.12 CBK24862.2 - 0.028 14.3 0.1 0.066 13.1 0.1 1.6 1 0 0 1 1 1 0 Heat shock factor binding protein 1 HHH PF00633.23 CBK24862.2 - 0.036 13.9 0.0 0.083 12.8 0.0 1.7 1 0 0 1 1 1 0 Helix-hairpin-helix motif Aldose_epim PF01263.20 CBK24863.2 - 7.6e-79 265.1 0.0 9e-79 264.9 0.0 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase Thyroglobulin_1 PF00086.18 CBK24863.2 - 0.13 11.9 0.0 0.28 10.9 0.0 1.5 1 0 0 1 1 1 0 Thyroglobulin type-1 repeat AMP-binding PF00501.28 CBK24864.2 - 1.3e-86 290.9 0.0 1.5e-86 290.6 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 CBK24864.2 - 0.0048 17.8 0.0 0.0098 16.9 0.0 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain EF-hand_4 PF12763.7 CBK24865.2 - 1.1e-94 311.3 0.0 8.6e-17 61.0 0.0 5.2 5 0 0 5 5 5 5 Cytoskeletal-regulatory complex EF hand EF-hand_7 PF13499.6 CBK24865.2 - 4.4e-30 103.9 14.1 0.00016 22.0 0.1 5.6 5 0 0 5 5 5 5 EF-hand domain pair EF-hand_1 PF00036.32 CBK24865.2 - 3.3e-17 60.7 16.2 0.14 11.8 0.1 9.1 10 0 0 10 10 10 5 EF hand EF-hand_8 PF13833.6 CBK24865.2 - 3.6e-15 55.5 1.1 0.69 9.8 0.0 5.3 5 0 0 5 5 5 5 EF-hand domain pair EF-hand_6 PF13405.6 CBK24865.2 - 2.5e-12 45.7 17.9 4.6 7.4 0.1 10.0 10 0 0 10 10 10 5 EF-hand domain ArAE_2 PF10334.9 CBK24865.2 - 5.5e-11 42.7 2.5 0.68 9.7 0.0 5.2 3 2 2 5 5 5 5 Aromatic acid exporter family member 2 End3 PF12761.7 CBK24865.2 - 4e-08 33.7 10.8 2.4 8.3 0.0 6.4 6 0 0 6 6 6 1 Actin cytoskeleton-regulatory complex protein END3 Secretin_N PF03958.17 CBK24865.2 - 0.0047 17.3 4.2 1.7e+02 2.7 0.0 5.3 5 0 0 5 5 5 0 Bacterial type II/III secretion system short domain VCBS PF13517.6 CBK24865.2 - 0.0057 17.2 9.4 97 3.7 0.1 5.3 5 0 0 5 5 5 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella EF-hand_5 PF13202.6 CBK24865.2 - 0.011 15.1 35.6 3.8 7.2 0.1 8.4 10 0 0 10 10 10 0 EF hand NigD_N PF12667.7 CBK24865.2 - 0.2 11.8 2.5 4e+02 1.2 0.0 4.9 5 0 0 5 5 5 0 NigD-like N-terminal OB domain Atg14 PF10186.9 CBK24865.2 - 0.2 10.7 9.0 0.55 9.3 9.0 1.7 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 pP_pnuc_1 PF18165.1 CBK24865.2 - 3.3 7.6 6.4 3.8e+02 0.9 0.0 5.0 6 0 0 6 6 6 0 Predicted pPIWI-associating nuclease PRKCSH PF07915.13 CBK24866.2 - 0.012 16.6 0.4 0.024 15.6 0.4 1.5 1 0 0 1 1 1 0 Glucosidase II beta subunit-like protein Ribosomal_L21e PF01157.18 CBK24867.2 - 3e-42 142.6 3.2 3e-42 142.6 3.2 1.5 2 0 0 2 2 2 1 Ribosomal protein L21e Put_Phosphatase PF06888.12 CBK24867.2 - 0.082 12.3 0.0 0.1 12.0 0.0 1.1 1 0 0 1 1 1 0 Putative Phosphatase PP2C PF00481.21 CBK24868.2 - 1.5e-24 87.0 0.0 1.7e-24 86.9 0.0 1.0 1 0 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 CBK24868.2 - 0.0017 18.3 0.0 0.002 18.1 0.0 1.1 1 0 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) Pkinase PF00069.25 CBK24869.2 - 0.00048 19.6 0.0 0.00079 18.9 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase PF00069.25 CBK24870.2 - 3.3e-14 52.9 0.0 2.5e-09 36.9 0.0 2.6 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CBK24870.2 - 9e-08 31.7 0.0 8.2e-05 22.0 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 CBK24870.2 - 0.011 14.5 0.0 0.016 14.0 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Kinase-like PF14531.6 CBK24870.2 - 0.035 13.4 0.0 1.6 8.0 0.0 2.1 2 0 0 2 2 2 0 Kinase-like HSP70 PF00012.20 CBK24871.2 - 2.4e-14 52.5 0.1 5e-14 51.4 0.1 1.4 1 0 0 1 1 1 1 Hsp70 protein RRM_2 PF04059.12 CBK24872.2 - 6.5e-25 87.2 0.3 1.1e-24 86.4 0.3 1.4 1 0 0 1 1 1 1 RNA recognition motif 2 Epimerase PF01370.21 CBK24873.2 - 5.4e-55 186.5 0.0 7.5e-55 186.0 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 CBK24873.2 - 8.3e-18 64.9 0.2 8.3e-18 64.9 0.2 2.1 2 1 1 3 3 3 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 CBK24873.2 - 5.7e-06 25.7 1.5 5.4e-05 22.5 1.5 2.2 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 CBK24873.2 - 5.8e-06 25.6 0.0 9.3e-06 24.9 0.0 1.4 1 0 0 1 1 1 1 RmlD substrate binding domain 3Beta_HSD PF01073.19 CBK24873.2 - 9.2e-06 24.9 0.6 3.1e-05 23.1 0.6 1.8 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 CBK24873.2 - 0.00038 19.7 0.2 0.002 17.3 0.0 2.0 2 0 0 2 2 2 1 Male sterility protein NICE-3 PF07406.11 CBK24873.2 - 0.13 12.2 0.0 0.24 11.4 0.0 1.3 1 0 0 1 1 1 0 NICE-3 protein Pox_MCEL PF03291.16 CBK24875.2 - 1.6e-44 152.4 0.5 2.1e-44 152.0 0.5 1.1 1 0 0 1 1 1 1 mRNA capping enzyme Methyltransf_25 PF13649.6 CBK24875.2 - 8.6e-13 48.8 0.0 1.7e-12 47.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CBK24875.2 - 1.6e-12 47.5 0.0 2.1e-12 47.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CBK24875.2 - 1.7e-10 41.5 0.0 3.2e-10 40.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CBK24875.2 - 3.6e-09 37.2 0.0 6.7e-09 36.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 CBK24875.2 - 5e-08 33.0 0.0 7.3e-08 32.4 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase domain MetW PF07021.12 CBK24875.2 - 0.0017 18.0 1.0 0.0033 17.0 0.0 1.9 3 0 0 3 3 3 1 Methionine biosynthesis protein MetW FtsJ PF01728.19 CBK24875.2 - 0.021 14.9 0.3 0.046 13.8 0.3 1.5 1 1 0 1 1 1 0 FtsJ-like methyltransferase TPMT PF05724.11 CBK24875.2 - 0.043 13.5 0.0 0.056 13.1 0.0 1.2 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) MORN PF02493.20 CBK24876.2 - 3.1e-31 105.4 50.1 0.00021 21.0 0.6 13.0 13 0 0 13 13 13 8 MORN repeat Ribosomal_L30 PF00327.20 CBK24876.2 - 7e-20 70.7 1.8 1.3e-19 69.8 1.8 1.5 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e CDC45 PF02724.14 CBK24876.2 - 0.0048 15.3 9.6 0.0055 15.1 9.6 1.1 1 0 0 1 1 1 1 CDC45-like protein DUF3048_C PF17479.2 CBK24876.2 - 0.0085 16.5 1.1 4.6 7.7 0.0 3.6 3 0 0 3 3 3 1 Protein of unknown function (DUF3048) C-terminal domain DUF2151 PF10221.9 CBK24876.2 - 0.21 10.1 9.0 0.29 9.7 9.0 1.1 1 0 0 1 1 1 0 Cell cycle and development regulator MVL PF12151.8 CBK24876.2 - 0.25 11.2 0.7 11 6.0 0.4 2.4 2 0 0 2 2 2 0 Mannan-binding protein AF-4 PF05110.13 CBK24876.2 - 0.36 8.8 15.7 0.46 8.5 15.7 1.0 1 0 0 1 1 1 0 AF-4 proto-oncoprotein DDHD PF02862.17 CBK24876.2 - 0.51 10.5 5.7 0.82 9.8 5.7 1.3 1 0 0 1 1 1 0 DDHD domain Tim54 PF11711.8 CBK24876.2 - 0.54 9.0 15.0 0.79 8.4 15.0 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Peptidase_S64 PF08192.11 CBK24876.2 - 0.6 8.5 6.5 0.9 8.0 6.5 1.2 1 0 0 1 1 1 0 Peptidase family S64 Zip PF02535.22 CBK24876.2 - 0.71 9.0 5.6 1.1 8.4 5.6 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter Dsh_C PF12316.8 CBK24876.2 - 0.8 10.1 2.2 1.2 9.5 2.2 1.2 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal DUF4050 PF13259.6 CBK24876.2 - 2.9 8.2 11.0 6.4 7.1 11.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4050) NPR3 PF03666.13 CBK24876.2 - 4.3 6.0 17.5 5.7 5.6 17.5 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Sec62 PF03839.16 CBK24876.2 - 7.4 6.0 21.6 11 5.4 21.6 1.2 1 0 0 1 1 1 0 Translocation protein Sec62 Fcf1 PF04900.12 CBK24877.2 - 5.3e-20 71.7 1.2 9.8e-20 70.8 1.2 1.4 1 0 0 1 1 1 1 Fcf1 PerC PF06069.11 CBK24877.2 - 0.21 11.9 1.9 0.63 10.3 0.7 2.2 2 0 0 2 2 2 0 PerC transcriptional activator Aa_trans PF01490.18 CBK24878.2 - 8.2e-44 149.9 30.4 9.9e-44 149.7 30.4 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 CBK24878.2 - 2.2e-07 30.3 22.0 4e-07 29.4 22.0 1.3 1 0 0 1 1 1 1 Tryptophan/tyrosine permease family SSrecog PF03531.14 CBK24879.2 - 2.3e-21 75.5 0.1 5.4e-21 74.3 0.1 1.7 1 0 0 1 1 1 1 Structure-specific recognition protein (SSRP1) POB3_N PF17292.2 CBK24879.2 - 5.9e-21 74.7 0.1 1.3e-20 73.5 0.1 1.6 1 0 0 1 1 1 1 POB3-like N-terminal PH domain Collagen PF01391.18 CBK24880.2 - 3.6e-06 26.6 10.6 3.6e-06 26.6 10.6 2.2 1 1 1 2 2 2 2 Collagen triple helix repeat (20 copies) TIM21 PF08294.11 CBK24881.2 - 3.8e-17 62.5 0.0 5e-17 62.1 0.0 1.1 1 0 0 1 1 1 1 TIM21 Coa1 PF08695.10 CBK24881.2 - 7.4e-05 22.5 0.0 0.00053 19.7 0.0 2.0 1 1 0 1 1 1 1 Cytochrome oxidase complex assembly protein 1 Ribosomal_S4e PF00900.20 CBK24881.2 - 0.038 13.9 0.0 1.6 8.7 0.0 2.6 2 1 0 2 2 2 0 Ribosomal family S4e MMR_HSR1_C PF08438.10 CBK24882.2 - 2.4e-36 124.7 0.3 3.8e-36 124.0 0.3 1.3 1 0 0 1 1 1 1 GTPase of unknown function C-terminal MMR_HSR1 PF01926.23 CBK24882.2 - 1.4e-20 73.4 0.0 4e-20 72.0 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 CBK24882.2 - 2.1e-09 37.1 0.2 2.6e-08 33.6 0.1 2.4 2 0 0 2 2 2 1 Ferrous iron transport protein B ATP_bind_1 PF03029.17 CBK24882.2 - 0.15 11.8 0.6 12 5.5 0.0 2.4 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein FH2 PF02181.23 CBK24883.2 - 1.6e-69 234.8 1.1 1.6e-69 234.8 1.1 1.4 2 0 0 2 2 2 1 Formin Homology 2 Domain Fe_bilin_red PF05996.12 CBK24883.2 - 0.0039 16.9 1.3 0.0074 16.0 1.3 1.4 1 0 0 1 1 1 1 Ferredoxin-dependent bilin reductase DUF1798 PF08807.10 CBK24883.2 - 0.02 15.0 1.7 0.045 13.9 1.7 1.7 1 0 0 1 1 1 0 Bacterial domain of unknown function (DUF1798) Peroxin-13_N PF04088.13 CBK24883.2 - 0.053 13.8 0.8 1.6 9.0 0.0 2.6 2 0 0 2 2 2 0 Peroxin 13, N-terminal region AAA_32 PF13654.6 CBK24883.2 - 0.097 11.4 5.1 7 5.3 0.0 2.4 2 0 0 2 2 2 0 AAA domain MPM1 PF17234.2 CBK24883.2 - 1.6 9.0 9.1 0.093 13.0 3.7 1.7 2 0 0 2 2 2 0 Mitochondrial peculiar membrane protein 1 CRT-like PF08627.10 CBK24884.2 - 4.5e-11 42.3 19.9 5.2e-07 28.9 4.0 2.1 1 1 1 2 2 2 2 CRT-like, chloroquine-resistance transporter-like EamA PF00892.20 CBK24884.2 - 1e-07 32.2 2.0 1e-07 32.2 2.0 3.2 3 1 0 3 3 3 1 EamA-like transporter family Nuc_sug_transp PF04142.15 CBK24884.2 - 1e-05 24.9 10.0 6.2e-05 22.3 10.0 2.0 1 1 0 1 1 1 1 Nucleotide-sugar transporter DUF4646 PF15496.6 CBK24884.2 - 0.0082 16.8 0.5 0.024 15.3 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4646) DUF2976 PF11190.8 CBK24884.2 - 0.41 10.5 15.3 0.18 11.6 1.5 3.6 3 1 0 3 3 3 0 Protein of unknown function (DUF2976) UDPGP PF01704.18 CBK24886.2 - 2.9e-15 55.9 0.0 4.6e-15 55.2 0.0 1.3 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase G8 PF10162.9 CBK24886.2 - 0.085 12.9 0.0 0.16 12.1 0.0 1.4 1 0 0 1 1 1 0 G8 domain DUF3737 PF12541.8 CBK24886.2 - 0.18 11.0 0.0 0.29 10.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3737) Nop PF01798.18 CBK24887.2 - 1.4e-83 279.8 0.0 1.4e-83 279.8 0.0 2.2 2 0 0 2 2 2 1 snoRNA binding domain, fibrillarin NOP5NT PF08156.13 CBK24887.2 - 1.4e-21 76.6 1.4 1.4e-21 76.6 1.4 2.5 2 1 0 2 2 2 1 NOP5NT (NUC127) domain GAGA_bind PF06217.12 CBK24887.2 - 0.3 11.3 16.0 0.47 10.7 16.0 1.3 1 0 0 1 1 1 0 GAGA binding protein-like family RR_TM4-6 PF06459.12 CBK24887.2 - 4.4 7.1 25.7 7.2 6.3 25.7 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 AAA_23 PF13476.6 CBK24887.2 - 4.8 7.6 23.4 0.85 10.1 18.8 2.1 2 0 0 2 2 2 0 AAA domain AAA_11 PF13086.6 CBK24887.2 - 4.9 6.9 17.4 8.1 6.1 17.4 1.3 1 0 0 1 1 1 0 AAA domain DDHD PF02862.17 CBK24887.2 - 5.4 7.1 10.9 11 6.2 9.9 2.0 2 0 0 2 2 2 0 DDHD domain SQS_PSY PF00494.19 CBK24888.2 - 6.2e-31 107.8 0.0 7.3e-31 107.6 0.0 1.0 1 0 0 1 1 1 1 Squalene/phytoene synthase UPF0004 PF00919.20 CBK24888.2 - 0.094 12.8 0.1 0.21 11.7 0.1 1.5 2 0 0 2 2 2 0 Uncharacterized protein family UPF0004 SDA1 PF05285.12 CBK24889.2 - 5.4e-34 118.2 76.3 5.4e-34 118.2 76.3 3.1 2 1 0 2 2 2 1 SDA1 NUC130_3NT PF08158.12 CBK24889.2 - 1.7e-17 63.5 0.1 1.7e-16 60.3 0.0 2.5 2 0 0 2 2 2 1 NUC130/3NT domain Thioredoxin PF00085.20 CBK24890.2 - 2.7e-25 88.3 0.0 9.6e-25 86.6 0.0 1.9 2 0 0 2 2 2 1 Thioredoxin ERp29 PF07749.12 CBK24890.2 - 7.3e-12 46.0 1.1 7.3e-12 46.0 1.1 2.0 2 0 0 2 2 1 1 Endoplasmic reticulum protein ERp29, C-terminal domain Thioredoxin_2 PF13098.6 CBK24890.2 - 3.4e-05 24.2 0.9 0.038 14.4 0.0 3.4 1 1 1 2 2 2 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 CBK24890.2 - 0.0064 16.8 0.1 0.24 11.7 0.0 3.0 2 1 1 3 3 3 1 Thioredoxin-like Thioredoxin_3 PF13192.6 CBK24890.2 - 0.025 14.6 0.0 0.28 11.3 0.0 2.5 2 1 0 2 2 2 0 Thioredoxin domain OST3_OST6 PF04756.13 CBK24890.2 - 0.039 13.3 0.0 0.064 12.6 0.0 1.3 1 0 0 1 1 1 0 OST3 / OST6 family, transporter family HyaE PF07449.11 CBK24890.2 - 0.055 13.4 0.0 0.16 12.0 0.0 1.7 1 0 0 1 1 1 0 Hydrogenase-1 expression protein HyaE DDE_Tnp_1_2 PF13586.6 CBK24890.2 - 0.11 12.9 1.5 0.3 11.5 0.0 2.4 2 1 1 3 3 3 0 Transposase DDE domain NUC153 PF08159.12 CBK24890.2 - 0.11 12.3 0.0 0.23 11.3 0.0 1.5 1 0 0 1 1 1 0 NUC153 domain EIIBC-GUT_N PF03612.14 CBK24890.2 - 1.1 9.0 5.6 2.1 8.1 5.6 1.4 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus CobT PF06213.12 CBK24890.2 - 1.8 7.9 14.8 2.7 7.3 14.8 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Paf1 PF03985.13 CBK24890.2 - 2 7.3 16.3 3.3 6.6 16.3 1.3 1 0 0 1 1 1 0 Paf1 Presenilin PF01080.17 CBK24890.2 - 2.1 7.1 4.2 3 6.5 4.2 1.2 1 0 0 1 1 1 0 Presenilin FtsJ PF01728.19 CBK24892.2 - 5.8e-54 182.9 0.1 9.2e-54 182.2 0.1 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_25 PF13649.6 CBK24892.2 - 0.15 12.8 0.2 16 6.3 0.0 2.7 1 1 1 2 2 2 0 Methyltransferase domain PHM7_ext PF12621.8 CBK24892.2 - 0.16 12.2 0.0 0.27 11.4 0.0 1.4 1 0 0 1 1 1 0 Extracellular tail, of 10TM putative phosphate transporter Ebp2 PF05890.12 CBK24893.2 - 4.1e-27 95.4 11.6 5.1e-27 95.1 11.6 1.1 1 0 0 1 1 1 1 Eukaryotic rRNA processing protein EBP2 MutS_I PF01624.20 CBK24893.2 - 0.0023 18.2 0.1 0.0031 17.7 0.1 1.2 1 0 0 1 1 1 1 MutS domain I Spectrin PF00435.21 CBK24893.2 - 0.015 15.8 2.9 0.06 13.8 2.9 1.9 1 1 0 1 1 1 0 Spectrin repeat BNIP2 PF12496.8 CBK24893.2 - 0.83 10.1 5.0 1.4 9.3 5.0 1.4 1 1 0 1 1 1 0 Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2 ALMT PF11744.8 CBK24893.2 - 1.4 7.7 4.3 1.6 7.5 4.3 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter Noc2 PF03715.13 CBK24894.2 - 1.9e-91 306.5 5.1 2.3e-91 306.2 5.1 1.0 1 0 0 1 1 1 1 Noc2p family Nop14 PF04147.12 CBK24894.2 - 5.5e-05 21.6 0.0 7.5e-05 21.2 0.0 1.2 1 0 0 1 1 1 1 Nop14-like family Imm49 PF15575.6 CBK24894.2 - 0.12 12.1 0.1 3.9 7.2 0.0 2.2 2 0 0 2 2 2 0 Immunity protein 49 RRM_1 PF00076.22 CBK24895.2 - 9.2e-34 115.1 0.0 1.1e-14 53.9 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RBM39linker PF15519.6 CBK24895.2 - 1.1e-07 32.8 0.1 3.2e-07 31.4 0.1 1.8 1 0 0 1 1 1 1 linker between RRM2 and RRM3 domains in RBM39 protein Limkain-b1 PF11608.8 CBK24895.2 - 3e-05 24.0 0.1 0.0003 20.8 0.1 2.4 2 0 0 2 2 2 1 Limkain b1 RRM_occluded PF16842.5 CBK24895.2 - 0.00033 20.5 0.0 1.4 8.8 0.0 3.1 3 0 0 3 3 3 2 Occluded RNA-recognition motif RRM_5 PF13893.6 CBK24895.2 - 0.026 14.1 0.0 0.49 10.0 0.0 2.5 1 1 1 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PHM7_cyt PF14703.6 CBK24895.2 - 0.037 14.2 0.7 1.1 9.5 0.7 3.0 1 1 0 1 1 1 0 Cytosolic domain of 10TM putative phosphate transporter Apt1 PF10351.9 CBK24895.2 - 0.35 9.7 13.6 0.45 9.3 13.6 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain NPR3 PF03666.13 CBK24895.2 - 7.3 5.3 14.5 11 4.7 14.5 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Rhodanese PF00581.20 CBK24896.2 - 2.6e-13 50.4 0.0 5.7e-06 26.8 0.0 2.3 2 0 0 2 2 2 2 Rhodanese-like domain ArsA_ATPase PF02374.15 CBK24897.2 - 5.7e-101 337.7 0.1 7.6e-101 337.3 0.1 1.1 1 0 0 1 1 1 1 Anion-transporting ATPase AAA_31 PF13614.6 CBK24897.2 - 2.2e-15 57.0 0.0 9.3e-15 55.0 0.0 2.0 1 1 0 1 1 1 1 AAA domain CbiA PF01656.23 CBK24897.2 - 5.6e-14 52.3 0.1 1.2e-12 48.0 0.1 2.2 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ParA PF10609.9 CBK24897.2 - 2.9e-10 40.0 0.6 7.8e-06 25.5 0.0 3.1 3 0 0 3 3 3 2 NUBPL iron-transfer P-loop NTPase SRP54 PF00448.22 CBK24897.2 - 3.1e-08 33.5 0.1 1.9e-05 24.4 0.0 2.8 3 0 0 3 3 3 1 SRP54-type protein, GTPase domain Fer4_NifH PF00142.18 CBK24897.2 - 5.5e-08 32.6 0.0 2.3e-07 30.5 0.0 2.0 2 0 0 2 2 2 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family MipZ PF09140.11 CBK24897.2 - 2.5e-05 23.7 0.1 0.0064 15.8 0.0 2.9 2 1 1 3 3 3 1 ATPase MipZ AAA_25 PF13481.6 CBK24897.2 - 8.3e-05 22.2 0.0 0.00024 20.7 0.0 1.6 1 1 0 1 1 1 1 AAA domain CBP_BcsQ PF06564.12 CBK24897.2 - 0.00014 21.4 0.0 0.00088 18.8 0.0 2.1 2 0 0 2 2 2 1 Cellulose biosynthesis protein BcsQ AAA_24 PF13479.6 CBK24897.2 - 0.0014 18.4 0.0 0.0062 16.3 0.0 2.0 1 1 0 1 1 1 1 AAA domain MeaB PF03308.16 CBK24897.2 - 0.0035 16.4 0.0 0.015 14.3 0.0 1.9 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB DUF2075 PF09848.9 CBK24897.2 - 0.0055 16.0 0.0 0.015 14.6 0.0 1.7 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) ATP_bind_1 PF03029.17 CBK24897.2 - 0.016 15.0 0.3 0.052 13.3 0.3 2.0 1 1 0 1 1 1 0 Conserved hypothetical ATP binding protein ResIII PF04851.15 CBK24897.2 - 0.019 15.0 0.1 0.052 13.6 0.1 1.7 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit Zeta_toxin PF06414.12 CBK24897.2 - 0.034 13.4 0.0 0.073 12.3 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin VirC1 PF07015.11 CBK24897.2 - 0.036 13.3 0.0 0.08 12.2 0.0 1.5 1 0 0 1 1 1 0 VirC1 protein DUF1611 PF07755.11 CBK24897.2 - 0.042 13.1 0.0 0.12 11.7 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1611_C) P-loop domain IstB_IS21 PF01695.17 CBK24897.2 - 0.046 13.4 0.0 0.08 12.7 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein ATPase PF06745.13 CBK24897.2 - 0.084 12.2 0.0 0.23 10.8 0.0 1.6 1 1 0 1 1 1 0 KaiC CobA_CobO_BtuR PF02572.15 CBK24897.2 - 0.09 13.0 0.0 4.7 7.4 0.0 2.3 2 0 0 2 2 2 0 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP AAA_18 PF13238.6 CBK24897.2 - 0.11 13.0 0.6 0.35 11.4 0.3 2.2 2 1 0 2 2 1 0 AAA domain DUF87 PF01935.17 CBK24897.2 - 0.12 12.4 0.0 0.26 11.3 0.0 1.5 1 1 0 1 1 1 0 Helicase HerA, central domain PRK PF00485.18 CBK24897.2 - 0.14 11.9 0.0 0.33 10.7 0.0 1.6 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family DUF2884 PF11101.8 CBK24897.2 - 0.61 9.6 2.4 2.4 7.6 1.5 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2884) DUF2847 PF11009.8 CBK24898.2 - 0.049 13.6 0.0 0.079 12.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2847) DUF4175 PF13779.6 CBK24900.2 - 0.082 10.8 9.7 0.093 10.6 9.7 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Pet191_N PF10203.9 CBK24900.2 - 0.1 12.9 1.5 0.19 12.0 1.5 1.5 1 0 0 1 1 1 0 Cytochrome c oxidase assembly protein PET191 XRN_N PF03159.18 CBK24900.2 - 1.8 8.0 8.5 1.8 7.9 7.2 1.6 1 1 1 2 2 2 0 XRN 5'-3' exonuclease N-terminus Prefoldin PF02996.17 CBK24901.2 - 9.8e-17 61.0 0.2 1.6e-16 60.3 0.1 1.4 1 1 0 1 1 1 1 Prefoldin subunit Prefoldin_2 PF01920.20 CBK24901.2 - 0.066 13.2 0.4 0.15 12.0 0.0 1.7 2 0 0 2 2 2 0 Prefoldin subunit ThiD2 PF17792.1 CBK24901.2 - 0.11 13.0 0.1 0.16 12.5 0.1 1.2 1 0 0 1 1 1 0 ThiD2 family FAT PF02259.23 CBK24902.2 - 0.0086 15.3 3.8 0.01 15.1 3.8 1.1 1 0 0 1 1 1 1 FAT domain DUF1635 PF07795.11 CBK24902.2 - 0.014 15.2 6.2 0.016 15.1 6.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1635) SlyX PF04102.12 CBK24902.2 - 0.034 14.8 7.3 3.8 8.2 3.9 2.3 1 1 1 2 2 2 0 SlyX HAP1_N PF04849.13 CBK24902.2 - 0.047 12.9 11.1 0.066 12.4 11.1 1.2 1 0 0 1 1 1 0 HAP1 N-terminal conserved region LUC7 PF03194.15 CBK24902.2 - 0.055 13.1 8.8 0.057 13.1 8.8 1.1 1 0 0 1 1 1 0 LUC7 N_terminus ADIP PF11559.8 CBK24902.2 - 0.064 13.3 12.2 0.091 12.8 12.2 1.2 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding CENP-H PF05837.12 CBK24902.2 - 0.084 13.3 14.0 0.13 12.7 14.0 1.2 1 0 0 1 1 1 0 Centromere protein H (CENP-H) Lectin_N PF03954.14 CBK24902.2 - 0.091 12.5 5.0 0.15 11.8 5.0 1.4 1 0 0 1 1 1 0 Hepatic lectin, N-terminal domain Herpes_UL6 PF01763.16 CBK24902.2 - 0.12 10.9 5.4 0.14 10.7 5.4 1.1 1 0 0 1 1 1 0 Herpesvirus UL6 like Sas10_Utp3 PF04000.15 CBK24902.2 - 0.17 12.5 4.0 0.32 11.6 4.0 1.5 1 0 0 1 1 1 0 Sas10/Utp3/C1D family Fmp27_WPPW PF10359.9 CBK24902.2 - 0.19 10.5 8.6 0.2 10.4 8.6 1.0 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain DUF3801 PF12687.7 CBK24902.2 - 0.21 11.7 9.1 0.25 11.4 9.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3801) Allexi_40kDa PF05549.11 CBK24902.2 - 0.23 11.0 3.6 0.27 10.7 3.6 1.1 1 0 0 1 1 1 0 Allexivirus 40kDa protein GLE1 PF07817.13 CBK24902.2 - 0.25 10.5 4.5 0.3 10.2 4.5 1.1 1 0 0 1 1 1 0 GLE1-like protein RPW8 PF05659.11 CBK24902.2 - 0.25 11.0 8.2 0.39 10.4 8.2 1.3 1 0 0 1 1 1 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 TP53IP5 PF15331.6 CBK24902.2 - 0.44 10.7 7.9 0.53 10.4 7.9 1.1 1 0 0 1 1 1 0 Cellular tumour antigen p53-inducible 5 Myotub-related PF06602.14 CBK24902.2 - 0.46 9.4 2.3 0.55 9.1 2.3 1.1 1 0 0 1 1 1 0 Myotubularin-like phosphatase domain Swi5 PF07061.11 CBK24902.2 - 0.56 10.3 14.6 0.15 12.2 9.4 2.1 1 1 1 2 2 2 0 Swi5 Exonuc_VII_L PF02601.15 CBK24902.2 - 0.8 9.2 6.4 0.81 9.2 6.4 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit ZapB PF06005.12 CBK24902.2 - 0.99 9.9 18.5 2.1 8.8 10.8 2.5 1 1 1 2 2 2 0 Cell division protein ZapB FapA PF03961.13 CBK24902.2 - 1.1 7.8 7.4 1.2 7.7 7.4 1.3 1 0 0 1 1 1 0 Flagellar Assembly Protein A Med8 PF10232.9 CBK24902.2 - 1.1 8.8 9.4 1.3 8.6 9.4 1.2 1 0 0 1 1 1 0 Mediator of RNA polymerase II transcription complex subunit 8 V_ATPase_I PF01496.19 CBK24902.2 - 1.2 7.0 5.3 1.1 7.1 5.3 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DivIC PF04977.15 CBK24902.2 - 1.2 9.0 11.1 5.6 6.8 5.2 2.3 1 1 1 2 2 2 0 Septum formation initiator YlqD PF11068.8 CBK24902.2 - 1.3 9.4 13.1 1.7 9.0 13.1 1.3 1 0 0 1 1 1 0 YlqD protein XhlA PF10779.9 CBK24902.2 - 1.3 9.3 10.3 2.2 8.5 10.1 1.5 1 1 0 1 1 1 0 Haemolysin XhlA DUF1664 PF07889.12 CBK24902.2 - 2 8.5 6.6 2.7 8.0 6.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) DUF4407 PF14362.6 CBK24902.2 - 2 7.7 10.2 2.3 7.5 10.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) AAA_13 PF13166.6 CBK24902.2 - 2.1 6.9 11.1 2.1 6.9 11.1 1.0 1 0 0 1 1 1 0 AAA domain Fzo_mitofusin PF04799.13 CBK24902.2 - 2.2 7.8 7.6 3.5 7.1 7.6 1.3 1 0 0 1 1 1 0 fzo-like conserved region DUF2951 PF11166.8 CBK24902.2 - 2.9 8.2 8.1 4.3 7.6 8.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2951) Mu-like_Pro PF10123.9 CBK24902.2 - 3.4 7.1 11.9 3.9 6.9 11.9 1.0 1 0 0 1 1 1 0 Mu-like prophage I protein Med9 PF07544.13 CBK24902.2 - 3.4 7.8 12.2 0.99 9.5 4.5 2.3 1 1 1 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 Selenoprotein_S PF06936.11 CBK24902.2 - 5.2 6.8 10.7 7 6.4 10.7 1.2 1 0 0 1 1 1 0 Selenoprotein S (SelS) DUF4337 PF14235.6 CBK24902.2 - 5.8 7.0 10.9 8 6.6 10.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) Ax_dynein_light PF10211.9 CBK24902.2 - 9.4 6.1 15.9 14 5.5 15.9 1.4 1 0 0 1 1 1 0 Axonemal dynein light chain ArfGap PF01412.18 CBK24903.2 - 3.3e-24 85.2 0.3 6e-24 84.4 0.3 1.5 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf IRF-2BP1_2 PF11261.8 CBK24903.2 - 0.053 13.1 0.5 0.11 12.1 0.5 1.4 1 0 0 1 1 1 0 Interferon regulatory factor 2-binding protein zinc finger KfrA_N PF11740.8 CBK24903.2 - 0.12 13.1 0.0 0.25 12.0 0.0 1.5 1 0 0 1 1 1 0 Plasmid replication region DNA-binding N-term DTHCT PF08070.11 CBK24903.2 - 0.14 12.9 80.8 0.15 12.8 10.5 6.7 1 1 3 4 4 4 0 DTHCT (NUC029) region Ribosomal_S21e PF01249.18 CBK24904.2 - 4.2e-28 97.3 0.1 4.8e-28 97.1 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S21e Clp_N PF02861.20 CBK24905.2 - 0.35 11.0 4.7 0.41 10.8 0.4 3.1 3 0 0 3 3 3 0 Clp amino terminal domain, pathogenicity island component vATP-synt_AC39 PF01992.16 CBK24906.2 - 1.1e-96 324.2 0.0 3.8e-96 322.5 0.0 1.7 1 1 0 1 1 1 1 ATP synthase (C/AC39) subunit Svf1_C PF17187.4 CBK24906.2 - 0.022 14.6 0.1 0.036 13.9 0.1 1.3 1 0 0 1 1 1 0 Svf1-like C-terminal lipocalin-like domain Pkinase PF00069.25 CBK24907.2 - 8.2e-66 222.1 0.0 1.1e-65 221.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBK24907.2 - 2.1e-46 158.3 0.0 3e-46 157.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CBK24907.2 - 8.7e-07 28.5 0.0 1.9e-06 27.4 0.0 1.6 1 1 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 CBK24907.2 - 0.019 13.9 0.1 0.019 13.9 0.1 2.3 2 1 1 3 3 3 0 Haspin like kinase domain APH PF01636.23 CBK24907.2 - 0.023 14.6 0.0 0.23 11.4 0.0 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 CBK24907.2 - 0.25 10.1 0.0 0.25 10.1 0.0 2.1 2 1 0 2 2 2 0 Fungal protein kinase Fis1_TPR_C PF14853.6 CBK24908.2 - 0.014 15.5 0.2 0.014 15.5 0.2 3.5 4 0 0 4 4 4 0 Fis1 C-terminal tetratricopeptide repeat TPR_19 PF14559.6 CBK24908.2 - 0.053 14.0 4.6 0.12 12.9 0.2 2.9 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 CBK24908.2 - 0.14 12.3 7.3 1.1 9.6 0.2 3.9 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.28 CBK24908.2 - 0.31 10.9 8.0 3.5 7.6 0.1 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat RRM_1 PF00076.22 CBK24909.2 - 1.6e-15 56.6 0.1 9e-15 54.3 0.0 2.2 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Myb_DNA-binding PF00249.31 CBK24909.2 - 7.2e-13 48.5 0.7 1.3e-12 47.6 0.7 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 CBK24909.2 - 2.8e-05 24.3 3.4 6.8e-05 23.0 3.4 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 CBK24909.2 - 0.0046 16.8 0.4 0.0095 15.8 0.4 1.6 1 0 0 1 1 1 1 Myb DNA-binding like Colicin PF01024.19 CBK24909.2 - 0.096 12.6 0.0 0.18 11.7 0.0 1.3 1 0 0 1 1 1 0 Colicin pore forming domain Pyr_redox_2 PF07992.14 CBK24910.2 - 2.6e-52 177.9 0.0 3.2e-52 177.6 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 CBK24910.2 - 6.1e-25 87.6 0.0 1.1e-24 86.8 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 CBK24910.2 - 1.1e-16 61.2 0.5 3.6e-14 53.1 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 CBK24910.2 - 6e-09 35.6 0.0 1.9e-06 27.4 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 CBK24910.2 - 2.2e-05 23.7 1.1 6e-05 22.3 0.9 1.8 3 0 0 3 3 3 1 FAD binding domain FAD_oxidored PF12831.7 CBK24910.2 - 9.7e-05 21.9 4.0 0.0055 16.1 2.8 2.6 2 1 1 3 3 3 1 FAD dependent oxidoreductase GIDA PF01134.22 CBK24910.2 - 0.00022 20.4 0.3 0.00035 19.8 0.3 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A HI0933_like PF03486.14 CBK24910.2 - 0.0011 17.8 0.4 0.0068 15.2 0.2 2.0 2 0 0 2 2 2 1 HI0933-like protein AlaDh_PNT_C PF01262.21 CBK24910.2 - 0.0012 18.2 0.0 0.0059 15.9 0.0 1.9 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain DAO PF01266.24 CBK24910.2 - 0.0012 18.5 0.6 1.6 8.3 0.4 2.5 3 0 0 3 3 3 2 FAD dependent oxidoreductase Thi4 PF01946.17 CBK24910.2 - 0.013 14.8 0.1 0.025 13.8 0.1 1.5 1 0 0 1 1 1 0 Thi4 family NAD_binding_8 PF13450.6 CBK24910.2 - 0.033 14.4 2.8 0.3 11.4 0.5 2.7 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain DUF3932 PF13068.6 CBK24910.2 - 0.13 12.5 0.1 0.25 11.6 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3932) eRF1_1 PF03463.15 CBK24911.2 - 1.3e-34 119.0 0.2 2e-34 118.4 0.2 1.3 1 0 0 1 1 1 1 eRF1 domain 1 eRF1_3 PF03465.15 CBK24911.2 - 9.2e-22 77.7 0.0 3e-21 76.0 0.0 1.9 2 0 0 2 2 2 1 eRF1 domain 3 eRF1_2 PF03464.15 CBK24911.2 - 3.4e-21 76.0 0.1 6.4e-21 75.1 0.1 1.5 1 0 0 1 1 1 1 eRF1 domain 2 peroxidase PF00141.23 CBK24911.2 - 0.0061 16.3 0.0 1.2 8.7 0.0 2.5 2 1 0 2 2 2 2 Peroxidase Pribosyltran_N PF13793.6 CBK24912.2 - 2.2e-44 150.1 0.2 1.9e-42 143.8 0.0 2.6 2 1 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.6 CBK24912.2 - 1.3e-28 100.3 0.1 2.5e-28 99.4 0.1 1.5 1 0 0 1 1 1 1 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.27 CBK24912.2 - 1.7e-07 30.9 0.1 4.1e-07 29.6 0.0 1.8 2 0 0 2 2 2 1 Phosphoribosyl transferase domain UPRTase PF14681.6 CBK24912.2 - 0.0056 16.1 0.0 0.016 14.6 0.0 1.6 1 1 0 1 1 1 1 Uracil phosphoribosyltransferase Ribosomal_L6 PF00347.23 CBK24913.2 - 4.9e-28 97.6 5.5 1.7e-15 57.5 0.8 2.1 2 0 0 2 2 2 2 Ribosomal protein L6 Rota_VP4_MID PF17477.2 CBK24913.2 - 0.049 13.0 0.0 0.063 12.6 0.0 1.2 1 0 0 1 1 1 0 Rotavirus VP4 membrane interaction domain PhoLip_ATPase_C PF16212.5 CBK24914.2 - 8.2e-54 183.0 29.5 8.2e-54 183.0 29.5 2.7 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 CBK24914.2 - 7.2e-17 60.8 1.7 4.1e-16 58.4 1.7 2.3 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 CBK24914.2 - 2.6e-09 37.7 0.3 0.0022 18.3 0.0 3.3 3 0 0 3 3 3 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 CBK24914.2 - 2.5e-07 30.7 0.0 8.3e-07 29.0 0.0 1.9 1 0 0 1 1 1 1 Cation transport ATPase (P-type) E1-E2_ATPase PF00122.20 CBK24914.2 - 8.4e-06 25.4 0.0 8.4e-06 25.4 0.0 2.6 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase_3 PF08282.12 CBK24914.2 - 0.00022 21.0 0.0 0.002 17.9 0.0 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase EntA_Immun PF08951.10 CBK24914.2 - 0.03 14.7 0.6 0.086 13.2 0.1 2.2 2 0 0 2 2 2 0 Enterocin A Immunity HAD PF12710.7 CBK24914.2 - 0.16 12.3 0.0 12 6.3 0.0 2.5 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase IATP PF04568.12 CBK24915.2 - 0.027 14.9 1.9 0.034 14.6 1.9 1.3 1 0 0 1 1 1 0 Mitochondrial ATPase inhibitor, IATP DUF4090 PF13319.6 CBK24915.2 - 0.058 13.6 1.0 0.074 13.3 1.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4090) ACBP PF00887.19 CBK24916.2 - 8.8e-29 99.6 0.3 1e-28 99.3 0.3 1.0 1 0 0 1 1 1 1 Acyl CoA binding protein FERM_M PF00373.18 CBK24916.2 - 0.13 12.6 0.1 0.26 11.7 0.1 1.3 1 1 0 1 1 1 0 FERM central domain Mucin PF01456.17 CBK24917.2 - 0.0098 15.9 17.7 0.01 15.8 17.7 1.1 1 0 0 1 1 1 1 Mucin-like glycoprotein NRBF2 PF08961.10 CBK24917.2 - 0.2 11.2 0.8 0.24 11.0 0.8 1.1 1 0 0 1 1 1 0 Nuclear receptor-binding factor 2, autophagy regulator B56 PF01603.20 CBK24918.2 - 8.5e-07 28.3 0.0 1.4e-06 27.6 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) PPR_2 PF13041.6 CBK24919.2 - 0.00066 19.8 0.1 0.001 19.2 0.1 1.3 1 0 0 1 1 1 1 PPR repeat family ERp29 PF07749.12 CBK24919.2 - 0.008 17.1 0.3 0.009 16.9 0.3 1.2 1 0 0 1 1 1 1 Endoplasmic reticulum protein ERp29, C-terminal domain PPR_long PF17177.4 CBK24919.2 - 0.021 14.2 0.0 0.023 14.0 0.0 1.0 1 0 0 1 1 1 0 Pentacotripeptide-repeat region of PRORP HSBP1 PF06825.12 CBK24920.2 - 0.0095 15.8 3.4 12 5.9 0.1 3.7 3 0 0 3 3 3 3 Heat shock factor binding protein 1 EXS PF03124.14 CBK24921.2 - 7.6e-57 193.1 38.5 7.6e-57 193.1 38.5 1.9 1 1 1 2 2 2 1 EXS family SPX PF03105.19 CBK24921.2 - 4.3e-28 99.3 11.2 2.2e-14 54.2 4.3 3.0 2 1 0 2 2 2 2 SPX domain CorA PF01544.18 CBK24921.2 - 1.3 8.3 5.6 0.5 9.6 0.1 2.3 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein Thioredoxin PF00085.20 CBK24923.2 - 4.8e-07 29.7 0.0 6.4e-07 29.3 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin DUF4083 PF13314.6 CBK24923.2 - 0.0041 17.0 0.3 0.0074 16.2 0.3 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4083) T4SS_CagC PF16943.5 CBK24923.2 - 0.11 12.7 0.0 0.17 12.1 0.0 1.3 1 0 0 1 1 1 0 Cag pathogenicity island, type IV secretory system HECT PF00632.25 CBK24924.2 - 1.3e-58 199.0 0.1 3.3e-58 197.6 0.0 1.7 2 0 0 2 2 2 1 HECT-domain (ubiquitin-transferase) Pro_isomerase PF00160.21 CBK24925.2 - 4.3e-50 170.1 0.3 5.1e-50 169.8 0.3 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD HSP20 PF00011.21 CBK24926.2 - 1.7e-27 95.5 1.5 2e-27 95.3 1.5 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 CBK24926.2 - 4.6e-12 45.3 0.0 7.8e-12 44.6 0.0 1.4 1 0 0 1 1 1 1 HSP20-like domain found in ArsA GalKase_gal_bdg PF10509.9 CBK24927.2 - 4.7e-17 61.3 0.2 1.2e-16 60.0 0.2 1.7 1 0 0 1 1 1 1 Galactokinase galactose-binding signature GHMP_kinases_C PF08544.13 CBK24927.2 - 1.3e-15 57.5 0.0 3.2e-15 56.2 0.0 1.7 1 0 0 1 1 1 1 GHMP kinases C terminal GHMP_kinases_N PF00288.26 CBK24927.2 - 2.3e-12 46.9 0.2 6e-12 45.6 0.2 1.7 1 0 0 1 1 1 1 GHMP kinases N terminal domain O-FucT PF10250.9 CBK24927.2 - 0.00014 21.7 0.1 0.00039 20.2 0.0 1.7 2 0 0 2 2 2 1 GDP-fucose protein O-fucosyltransferase Aa_trans PF01490.18 CBK24928.2 - 1.6e-12 46.9 5.5 1.8e-12 46.7 5.5 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein RED_N PF07808.13 CBK24929.2 - 2.2e-10 40.6 2.9 2.2e-10 40.6 2.9 2.8 1 1 2 3 3 3 2 RED-like protein N-terminal region tRNA-synt_2b PF00587.25 CBK24930.2 - 5.5e-27 94.9 0.0 1e-26 94.0 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 CBK24930.2 - 8.8e-05 22.6 0.1 0.00023 21.3 0.1 1.7 1 0 0 1 1 1 1 Anticodon binding domain zinc_ribbon_13 PF09855.9 CBK24930.2 - 0.02 15.1 0.1 0.092 12.9 0.1 2.2 2 0 0 2 2 2 0 Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082) GHMP_kinases_C PF08544.13 CBK24932.2 - 4.3e-10 39.8 0.0 9e-10 38.8 0.0 1.6 1 0 0 1 1 1 1 GHMP kinases C terminal Ribosomal_L11_N PF03946.14 CBK24933.2 - 4e-18 65.0 0.5 6.6e-18 64.3 0.5 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.19 CBK24933.2 - 2.9e-17 62.9 0.1 4.6e-17 62.3 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain IF4E PF01652.18 CBK24934.2 - 4.1e-32 111.2 0.5 5.2e-32 110.8 0.5 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E LRR_4 PF12799.7 CBK24935.2 - 2.9e-26 91.1 44.5 1.4e-07 31.7 2.1 5.1 3 2 2 5 5 5 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CBK24935.2 - 7.8e-26 89.6 30.0 2.8e-11 43.0 5.4 3.3 2 1 1 3 3 3 3 Leucine rich repeat LRR_9 PF14580.6 CBK24935.2 - 3.5e-07 29.9 14.6 0.001 18.6 4.8 2.8 1 1 2 3 3 3 3 Leucine-rich repeat LRR_1 PF00560.33 CBK24935.2 - 8.3e-05 22.6 34.3 0.96 10.2 2.2 7.8 7 1 0 7 7 7 3 Leucine Rich Repeat FNIP PF05725.12 CBK24935.2 - 0.00031 20.8 1.3 4.5 7.5 1.3 5.0 1 1 0 1 1 1 1 FNIP Repeat RsmF_methylt_CI PF17126.5 CBK24935.2 - 0.0004 20.4 0.3 4 7.5 0.0 3.8 1 1 4 5 5 5 1 RsmF rRNA methyltransferase first C-terminal domain ADK PF00406.22 CBK24936.2 - 3.5e-59 199.2 0.0 4.3e-59 198.9 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 CBK24936.2 - 5.2e-26 91.7 0.0 1.2e-25 90.5 0.0 1.5 2 0 0 2 2 2 1 AAA domain ADK_lid PF05191.14 CBK24936.2 - 1.4e-19 69.8 0.0 4.1e-19 68.3 0.0 1.9 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_18 PF13238.6 CBK24936.2 - 3.2e-05 24.5 0.0 0.00012 22.6 0.0 1.8 2 0 0 2 2 2 1 AAA domain Hydin_ADK PF17213.3 CBK24936.2 - 3.7e-05 24.1 0.0 0.042 14.1 0.0 2.2 1 1 1 2 2 2 2 Hydin Adenylate kinase-like domain AAA_33 PF13671.6 CBK24936.2 - 0.00026 21.1 0.0 0.00071 19.8 0.0 1.6 1 1 0 2 2 2 1 AAA domain AAA PF00004.29 CBK24936.2 - 0.11 13.0 0.0 0.21 12.0 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 CBK24936.2 - 0.22 11.4 0.0 0.36 10.7 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain DAP3 PF10236.9 CBK24936.2 - 0.22 10.6 0.0 0.65 9.1 0.0 1.7 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 Rpr2 PF04032.16 CBK24937.2 - 2.1e-06 27.9 1.1 2.1e-06 27.9 1.1 2.1 1 1 1 2 2 2 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain Ribosomal_L28 PF00830.19 CBK24937.2 - 0.0052 16.9 1.6 0.0052 16.9 1.6 1.8 2 0 0 2 2 2 1 Ribosomal L28 family Sec62 PF03839.16 CBK24937.2 - 0.2 11.1 2.3 0.28 10.6 2.3 1.3 1 0 0 1 1 1 0 Translocation protein Sec62 Myotub-related PF06602.14 CBK24939.2 - 6e-118 393.8 0.0 7.5e-118 393.5 0.0 1.0 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain DSPc PF00782.20 CBK24939.2 - 0.00056 19.7 0.0 0.00095 19.0 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 CBK24939.2 - 0.074 13.0 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 Tyrosine phosphatase family Laminin_G_3 PF13385.6 CBK24940.2 - 0.0012 19.0 0.6 0.0044 17.2 0.6 1.8 1 1 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily Ribosomal_S24e PF01282.19 CBK24942.2 - 3.5e-27 94.2 0.0 6.6e-27 93.3 0.0 1.5 1 1 0 1 1 1 1 Ribosomal protein S24e CDC45 PF02724.14 CBK24943.2 - 3.1e-113 379.3 21.7 6.5e-71 239.5 19.8 3.0 1 1 1 2 2 2 2 CDC45-like protein ORC4_C PF14629.6 CBK24943.2 - 0.02 14.2 0.1 0.064 12.6 0.0 1.9 2 0 0 2 2 2 0 Origin recognition complex (ORC) subunit 4 C-terminus Histone PF00125.24 CBK24944.2 - 1.7e-42 144.9 3.8 1.8e-42 144.8 3.8 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 CBK24944.2 - 0.00036 20.6 0.0 0.00059 19.9 0.0 1.3 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TFIID-31kDa PF02291.15 CBK24944.2 - 0.023 14.8 0.1 0.047 13.8 0.0 1.5 1 1 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit CENP-S PF15630.6 CBK24944.2 - 0.026 14.9 0.1 0.043 14.2 0.1 1.3 1 0 0 1 1 1 0 CENP-S protein TAF PF02969.17 CBK24944.2 - 0.092 12.9 0.5 0.19 11.9 0.5 1.6 1 1 0 1 1 1 0 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.23 CBK24944.2 - 0.12 12.6 0.6 0.25 11.6 0.6 1.5 1 1 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone DUF4840 PF16128.5 CBK24944.2 - 0.14 12.2 0.0 0.2 11.7 0.0 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4840) zf-C3HC4_3 PF13920.6 CBK24945.2 - 0.00038 20.3 4.9 0.00075 19.3 4.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 CBK24945.2 - 0.021 14.7 6.1 0.021 14.7 6.1 1.6 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 CBK24945.2 - 0.025 14.5 6.0 0.051 13.5 6.0 1.5 1 0 0 1 1 1 0 zinc-RING finger domain zf-C4_ClpX PF06689.13 CBK24945.2 - 0.042 13.7 5.3 0.085 12.8 5.3 1.5 1 0 0 1 1 1 0 ClpX C4-type zinc finger zf-RING_2 PF13639.6 CBK24945.2 - 0.095 13.1 6.1 0.19 12.1 6.1 1.5 1 0 0 1 1 1 0 Ring finger domain zf-RING_10 PF16685.5 CBK24945.2 - 0.77 9.9 6.2 7.7 6.7 6.5 2.1 1 1 1 2 2 2 0 zinc RING finger of MSL2 Zn_Tnp_IS1595 PF12760.7 CBK24945.2 - 5 7.2 6.5 21 5.2 2.6 2.4 2 0 0 2 2 2 0 Transposase zinc-ribbon domain Mito_carr PF00153.27 CBK24946.2 - 1.1e-54 182.3 5.7 4.7e-22 77.7 0.2 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Pkinase PF00069.25 CBK24947.2 - 7.8e-23 81.2 0.0 4.9e-22 78.5 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBK24947.2 - 5.8e-08 32.3 0.0 6.6e-07 28.9 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Mito_carr PF00153.27 CBK24948.2 - 4.1e-46 154.9 4.8 8.7e-18 64.0 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein RRM_1 PF00076.22 CBK24949.2 - 3.2e-31 106.9 0.0 3.7e-17 61.9 0.1 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 CBK24949.2 - 0.0058 16.5 0.0 0.0094 15.8 0.0 1.3 1 0 0 1 1 1 1 Occluded RNA-recognition motif RRM_5 PF13893.6 CBK24949.2 - 0.012 15.2 0.0 0.072 12.7 0.0 2.0 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RR_TM4-6 PF06459.12 CBK24949.2 - 3.4 7.4 20.2 5.1 6.9 20.2 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Pox_Ag35 PF03286.14 CBK24949.2 - 7.9 6.2 21.9 14 5.4 21.9 1.4 1 0 0 1 1 1 0 Pox virus Ag35 surface protein CTP_transf_1 PF01148.20 CBK24950.2 - 1.8e-05 24.7 3.6 2.2e-05 24.4 3.6 1.1 1 0 0 1 1 1 1 Cytidylyltransferase family adh_short_C2 PF13561.6 CBK24953.2 - 2.5e-54 184.3 0.0 3e-54 184.1 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 CBK24953.2 - 1.4e-52 178.1 0.0 2.1e-52 177.4 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 CBK24953.2 - 2.7e-10 40.5 0.0 3.9e-10 39.9 0.0 1.1 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 CBK24953.2 - 0.0084 15.5 0.0 0.015 14.7 0.0 1.3 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Epimerase PF01370.21 CBK24953.2 - 0.056 12.9 0.0 0.1 12.0 0.0 1.4 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 CBK24953.2 - 0.13 11.2 0.0 0.19 10.7 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Mito_carr PF00153.27 CBK24954.2 - 9.2e-35 118.5 6.4 1.6e-17 63.2 0.1 3.0 1 1 2 3 3 3 3 Mitochondrial carrier protein DAD PF02109.16 CBK24955.2 - 6.5e-34 116.5 7.5 7.1e-34 116.4 7.5 1.0 1 0 0 1 1 1 1 DAD family E1-E2_ATPase PF00122.20 CBK24955.2 - 0.18 11.3 0.1 0.24 10.9 0.1 1.2 1 0 0 1 1 1 0 E1-E2 ATPase ABC_tran PF00005.27 CBK24956.2 - 3.9e-73 244.4 2.5 1.2e-37 129.5 0.0 2.7 3 0 0 3 3 2 2 ABC transporter ABC_membrane PF00664.23 CBK24956.2 - 2.4e-28 99.6 16.3 2.4e-28 99.6 16.3 1.7 2 0 0 2 2 1 1 ABC transporter transmembrane region AAA_16 PF13191.6 CBK24956.2 - 1.4e-11 45.1 0.0 0.00028 21.3 0.0 2.8 2 1 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 CBK24956.2 - 3.6e-11 43.5 2.0 0.00078 19.7 0.0 4.1 2 2 0 2 2 2 2 AAA domain AAA PF00004.29 CBK24956.2 - 1.6e-09 38.3 0.4 0.00022 21.7 0.0 3.9 2 2 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) SMC_N PF02463.19 CBK24956.2 - 4.5e-09 36.1 12.7 0.00081 18.9 0.0 4.5 4 1 1 5 5 4 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 CBK24956.2 - 1.4e-08 34.3 0.3 0.0034 17.1 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 CBK24956.2 - 3.9e-08 33.4 0.0 0.011 15.7 0.0 2.7 2 0 0 2 2 2 2 RsgA GTPase G-alpha PF00503.20 CBK24956.2 - 3.1e-07 29.9 0.2 0.015 14.4 0.0 2.8 3 0 0 3 3 3 2 G-protein alpha subunit ABC_ATPase PF09818.9 CBK24956.2 - 8.4e-07 28.1 0.7 0.025 13.4 0.0 3.0 3 0 0 3 3 3 2 Predicted ATPase of the ABC class AAA_21 PF13304.6 CBK24956.2 - 1.3e-06 28.4 7.2 0.76 9.5 0.2 4.4 4 1 0 5 5 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_25 PF13481.6 CBK24956.2 - 2.5e-06 27.2 0.2 0.71 9.4 0.0 4.0 4 0 0 4 4 4 2 AAA domain AAA_30 PF13604.6 CBK24956.2 - 3.1e-06 27.0 0.6 0.22 11.2 0.2 3.8 3 1 0 3 3 3 2 AAA domain AAA_5 PF07728.14 CBK24956.2 - 3.2e-06 27.2 0.5 0.6 10.1 0.0 4.4 4 0 0 4 4 4 1 AAA domain (dynein-related subfamily) AAA_23 PF13476.6 CBK24956.2 - 7e-06 26.7 14.3 0.028 14.9 0.0 3.4 3 0 0 3 3 3 2 AAA domain SbcCD_C PF13558.6 CBK24956.2 - 1.4e-05 25.2 4.9 0.065 13.5 1.0 3.8 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit TniB PF05621.11 CBK24956.2 - 2.7e-05 23.7 0.1 4.6 6.6 0.0 4.2 4 0 0 4 4 4 0 Bacterial TniB protein RNA_helicase PF00910.22 CBK24956.2 - 5.2e-05 23.6 0.2 1.1 9.7 0.0 4.0 4 0 0 4 4 4 1 RNA helicase IstB_IS21 PF01695.17 CBK24956.2 - 0.00012 21.9 0.1 1.3 8.7 0.0 3.8 4 0 0 4 4 3 1 IstB-like ATP binding protein AAA_7 PF12775.7 CBK24956.2 - 0.00013 21.6 0.1 0.17 11.4 0.0 2.5 2 0 0 2 2 2 2 P-loop containing dynein motor region MMR_HSR1 PF01926.23 CBK24956.2 - 0.00013 22.0 0.1 0.52 10.4 0.0 3.3 2 0 0 2 2 2 1 50S ribosome-binding GTPase Rad17 PF03215.15 CBK24956.2 - 0.00024 21.1 0.0 0.17 11.8 0.0 2.6 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_11 PF13086.6 CBK24956.2 - 0.00032 20.6 1.4 0.0088 15.9 1.4 2.6 2 1 0 2 2 2 1 AAA domain AAA_24 PF13479.6 CBK24956.2 - 0.00059 19.6 0.2 1.1 8.9 0.1 3.1 2 2 0 2 2 2 1 AAA domain AAA_15 PF13175.6 CBK24956.2 - 0.00066 19.5 12.5 0.31 10.7 0.0 3.2 2 1 0 2 2 2 1 AAA ATPase domain NB-ARC PF00931.22 CBK24956.2 - 0.00075 18.8 0.2 0.96 8.6 0.0 2.7 2 0 0 2 2 2 1 NB-ARC domain CDC45 PF02724.14 CBK24956.2 - 0.0009 17.7 6.0 0.0015 17.0 6.0 1.3 1 0 0 1 1 1 1 CDC45-like protein AAA_18 PF13238.6 CBK24956.2 - 0.00094 19.7 9.0 0.65 10.5 0.1 4.5 5 0 0 5 5 4 2 AAA domain AAA_33 PF13671.6 CBK24956.2 - 0.0011 19.2 0.1 1.5 9.0 0.0 2.9 2 1 0 2 2 2 1 AAA domain Tim54 PF11711.8 CBK24956.2 - 0.0011 17.8 3.6 0.0019 17.0 3.6 1.2 1 0 0 1 1 1 1 Inner membrane protein import complex subunit Tim54 PRK PF00485.18 CBK24956.2 - 0.0011 18.7 0.2 0.45 10.2 0.1 2.6 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family DEAD PF00270.29 CBK24956.2 - 0.0017 18.2 0.8 0.23 11.2 0.1 3.4 2 2 0 2 2 2 1 DEAD/DEAH box helicase DUF87 PF01935.17 CBK24956.2 - 0.0017 18.5 5.0 0.22 11.6 0.0 3.7 3 0 0 3 3 3 1 Helicase HerA, central domain ATP_bind_1 PF03029.17 CBK24956.2 - 0.0029 17.4 0.4 0.27 11.0 0.0 2.7 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein Zeta_toxin PF06414.12 CBK24956.2 - 0.0059 15.9 0.0 2.3 7.5 0.0 2.5 2 0 0 2 2 2 1 Zeta toxin Roc PF08477.13 CBK24956.2 - 0.006 16.8 0.0 3.6 7.8 0.0 3.5 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase Sigma54_activat PF00158.26 CBK24956.2 - 0.0062 16.3 0.0 4.1 7.1 0.0 3.2 3 0 0 3 3 3 0 Sigma-54 interaction domain MoaE PF02391.17 CBK24956.2 - 0.0063 16.8 1.1 5.1 7.4 0.1 3.6 3 1 0 3 3 2 0 MoaE protein Raftlin PF15250.6 CBK24956.2 - 0.0088 14.8 6.9 0.015 14.1 6.9 1.2 1 0 0 1 1 1 1 Raftlin MeaB PF03308.16 CBK24956.2 - 0.013 14.5 0.0 0.62 9.0 0.0 2.4 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB APS_kinase PF01583.20 CBK24956.2 - 0.015 15.2 0.1 1.8 8.4 0.0 2.7 2 0 0 2 2 2 0 Adenylylsulphate kinase AAA_14 PF13173.6 CBK24956.2 - 0.017 15.2 0.0 7.1 6.7 0.0 3.1 3 0 0 3 3 2 0 AAA domain Mg_chelatase PF01078.21 CBK24956.2 - 0.017 14.5 0.0 1.5 8.2 0.0 2.5 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI KAP_NTPase PF07693.14 CBK24956.2 - 0.018 14.3 0.1 0.34 10.1 0.1 2.4 2 0 0 2 2 2 0 KAP family P-loop domain Connexin PF00029.19 CBK24956.2 - 0.025 14.3 5.8 0.016 15.0 3.2 2.0 2 0 0 2 2 1 0 Connexin NACHT PF05729.12 CBK24956.2 - 0.027 14.4 0.1 2 8.3 0.1 2.6 2 0 0 2 2 2 0 NACHT domain Dynamin_N PF00350.23 CBK24956.2 - 0.058 13.5 3.5 13 5.8 0.0 3.5 3 0 0 3 3 3 0 Dynamin family ATP-synt_ab PF00006.25 CBK24956.2 - 0.065 12.9 0.1 4 7.0 0.0 2.3 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_28 PF13521.6 CBK24956.2 - 0.066 13.5 0.7 3.6 7.8 0.0 2.9 2 0 0 2 2 2 0 AAA domain AP-5_subunit_s1 PF15001.6 CBK24956.2 - 0.08 12.9 0.7 0.18 11.8 0.7 1.5 1 0 0 1 1 1 0 AP-5 complex subunit sigma-1 NTPase_1 PF03266.15 CBK24956.2 - 0.087 12.7 1.6 11 5.9 0.0 3.1 4 0 0 4 4 2 0 NTPase Sec62 PF03839.16 CBK24956.2 - 0.1 12.1 4.2 0.21 11.0 4.2 1.5 1 0 0 1 1 1 0 Translocation protein Sec62 DUF4337 PF14235.6 CBK24956.2 - 0.11 12.6 4.4 0.32 11.1 4.4 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) RNA_pol_Rpc4 PF05132.14 CBK24956.2 - 0.13 12.7 5.1 0.27 11.7 5.1 1.4 1 0 0 1 1 1 0 RNA polymerase III RPC4 AAA_19 PF13245.6 CBK24956.2 - 0.15 12.4 3.0 13 6.1 0.1 3.8 3 2 0 3 3 3 0 AAA domain Coilin_N PF15862.5 CBK24956.2 - 0.43 10.4 13.8 0.22 11.3 11.2 1.9 2 0 0 2 2 1 0 Coilin N-terminus DUF913 PF06025.12 CBK24956.2 - 0.47 9.4 2.6 1.1 8.2 2.6 1.5 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) RR_TM4-6 PF06459.12 CBK24956.2 - 0.49 10.2 13.2 0.87 9.4 13.2 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Vfa1 PF08432.10 CBK24956.2 - 0.5 10.7 18.8 2.5 8.4 16.9 2.2 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 DUF4604 PF15377.6 CBK24956.2 - 0.82 10.1 20.9 1.8 8.9 20.9 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4604) YqfQ PF14181.6 CBK24956.2 - 2.4 8.3 17.9 4.9 7.3 17.9 1.5 1 0 0 1 1 1 0 YqfQ-like protein DUF2207 PF09972.9 CBK24956.2 - 5.4 5.7 10.7 2.1 7.0 4.0 2.7 1 1 1 2 2 2 0 Predicted membrane protein (DUF2207) NPR3 PF03666.13 CBK24956.2 - 6.8 5.4 8.6 12 4.5 8.6 1.3 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 KH_1 PF00013.29 CBK24957.2 - 6.1e-46 154.1 14.8 1.1e-07 31.5 0.0 10.2 10 0 0 10 10 10 10 KH domain SLS PF14611.6 CBK24957.2 - 7.1e-14 52.2 13.8 0.12 12.2 0.0 7.4 1 1 6 8 8 8 5 Mitochondrial inner-membrane-bound regulator KH_2 PF07650.17 CBK24957.2 - 7.2e-10 38.6 16.8 0.046 13.5 0.1 6.4 6 1 0 6 6 6 3 KH domain Acyl_transf_1 PF00698.21 CBK24957.2 - 0.00016 21.3 9.0 0.0078 15.7 1.8 2.7 2 0 0 2 2 2 2 Acyl transferase domain KH_4 PF13083.6 CBK24957.2 - 0.0011 18.9 4.1 0.11 12.3 0.0 4.7 5 1 0 5 5 5 1 KH domain KH_5 PF13184.6 CBK24957.2 - 0.0013 18.7 8.2 0.65 10.1 0.2 5.2 6 0 0 6 6 6 1 NusA-like KH domain Secretin_N PF03958.17 CBK24957.2 - 0.0017 18.7 4.8 14 6.1 0.1 5.6 5 1 1 6 6 6 1 Bacterial type II/III secretion system short domain TubC_N PF18563.1 CBK24957.2 - 0.043 13.8 0.1 10 6.2 0.0 3.5 2 1 1 3 3 3 0 TubC N-terminal docking domain TPR_6 PF13174.6 CBK24957.2 - 0.084 13.5 0.5 1.1e+02 3.7 0.0 4.1 3 0 0 3 3 3 0 Tetratricopeptide repeat DNA_pol3_beta_3 PF02768.15 CBK24957.2 - 2.1 8.2 8.6 9.3 6.1 0.4 3.7 3 1 0 3 3 3 0 DNA polymerase III beta subunit, C-terminal domain KH_1 PF00013.29 CBK24958.2 - 7.3e-15 54.6 0.4 3.1e-10 39.7 0.2 2.6 2 0 0 2 2 2 2 KH domain KH_2 PF07650.17 CBK24958.2 - 0.00015 21.6 1.7 0.00063 19.5 1.3 2.4 1 1 1 2 2 2 1 KH domain MIS13 PF08202.11 CBK24958.2 - 0.006 15.9 6.5 0.01 15.2 6.5 1.4 1 0 0 1 1 1 1 Mis12-Mtw1 protein family SLS PF14611.6 CBK24958.2 - 0.0085 15.9 3.2 0.034 14.0 1.6 2.4 1 1 1 2 2 2 1 Mitochondrial inner-membrane-bound regulator KH_5 PF13184.6 CBK24958.2 - 0.0094 16.0 2.7 0.043 13.9 0.2 2.7 3 0 0 3 3 3 1 NusA-like KH domain HLH PF00010.26 CBK24958.2 - 0.021 14.8 1.3 0.064 13.2 0.6 2.1 2 0 0 2 2 2 0 Helix-loop-helix DNA-binding domain SpoIISA_toxin PF14171.6 CBK24958.2 - 0.026 14.2 1.7 0.044 13.5 1.2 1.6 1 1 0 1 1 1 0 Toxin SpoIISA, type II toxin-antitoxin system HSBP1 PF06825.12 CBK24958.2 - 0.55 10.1 3.1 3.1 7.7 0.1 3.1 3 0 0 3 3 3 0 Heat shock factor binding protein 1 ABC_tran_CTD PF16326.5 CBK24958.2 - 3.2 8.1 10.1 1.6 9.0 1.2 3.4 3 1 0 3 3 3 0 ABC transporter C-terminal domain SOGA PF11365.8 CBK24958.2 - 4.2 8.6 14.6 10 7.4 4.1 3.0 1 1 2 3 3 3 0 Protein SOGA DNA_pol_B_2 PF03175.13 CBK24960.2 - 3.5e-17 62.4 9.0 3.6e-14 52.5 3.1 2.8 2 1 0 2 2 2 2 DNA polymerase type B, organellar and viral Ribosomal_L44 PF00935.19 CBK24961.2 - 2.5e-30 104.7 13.1 4.2e-30 104.0 13.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L44 Phage_coat PF09063.10 CBK24961.2 - 0.14 12.2 0.0 33 4.5 0.0 2.7 2 0 0 2 2 2 0 Phage PP7 coat protein Rpr2 PF04032.16 CBK24961.2 - 0.38 11.1 4.7 0.22 11.8 1.5 2.4 3 0 0 3 3 3 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain zf_CCCH_4 PF18345.1 CBK24961.2 - 0.54 10.4 2.0 4.5e+02 1.1 0.0 4.9 4 0 0 4 4 4 0 Zinc finger domain AnfG_VnfG PF03139.15 CBK24961.2 - 1.8 8.7 10.7 46 4.2 0.1 4.5 4 0 0 4 4 4 0 Vanadium/alternative nitrogenase delta subunit Ribosomal_L33 PF00471.20 CBK24961.2 - 2 8.9 10.3 2.2 8.8 3.8 2.7 2 0 0 2 2 2 0 Ribosomal protein L33 MMtag PF10159.9 CBK24962.2 - 5.7e-11 42.6 1.1 8.7e-11 42.0 1.1 1.3 1 0 0 1 1 1 1 Multiple myeloma tumor-associated A2M PF00207.22 CBK24962.2 - 0.091 12.6 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 Alpha-2-macroglobulin family DUF563 PF04577.14 CBK24963.2 - 3.6e-27 95.9 0.1 7.8e-27 94.8 0.1 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF563) HSP70 PF00012.20 CBK24964.2 - 3.2e-07 28.9 0.0 3.7e-07 28.7 0.0 1.1 1 0 0 1 1 1 1 Hsp70 protein MORN PF02493.20 CBK24965.2 - 0.00012 21.7 11.2 0.04 13.8 3.8 4.0 4 0 0 4 4 4 2 MORN repeat PaREP1 PF05942.11 CBK24965.2 - 0.0071 16.3 8.7 0.018 15.0 8.7 1.7 1 0 0 1 1 1 1 Archaeal PaREP1/PaREP8 family CxC5 PF18718.1 CBK24965.2 - 0.077 13.1 0.0 0.2 11.7 0.0 1.7 1 0 0 1 1 1 0 CxC5 like cysteine cluster associated with KDZ transposases DUF5401 PF17380.2 CBK24965.2 - 0.091 10.8 13.2 0.12 10.4 13.2 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5401) Hydrolase_2 PF07486.12 CBK24965.2 - 0.37 11.7 2.7 0.74 10.7 1.2 2.3 2 1 0 2 2 2 0 Cell Wall Hydrolase AP1AR PF15745.5 CBK24965.2 - 1.7 8.2 13.1 0.34 10.5 9.4 1.6 2 0 0 2 2 2 0 AP-1 complex-associated regulatory protein E1_DerP2_DerF2 PF02221.15 CBK24966.2 - 2.2e-15 57.2 0.0 2.5e-15 57.1 0.0 1.0 1 0 0 1 1 1 1 ML domain AMP-binding PF00501.28 CBK24967.2 - 2.8e-11 42.7 0.0 8.5e-11 41.1 0.0 1.9 2 0 0 2 2 2 1 AMP-binding enzyme PP-binding PF00550.25 CBK24967.2 - 2.6e-08 34.1 0.0 6.9e-08 32.7 0.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site AMP-binding_C PF13193.6 CBK24967.2 - 0.00012 22.9 1.3 0.00022 22.1 1.3 1.4 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain AMP-binding_C_2 PF14535.6 CBK24967.2 - 0.0011 19.2 1.4 0.0014 18.9 0.1 1.9 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain O_Spanin_T7 PF17531.2 CBK24967.2 - 0.044 13.8 0.2 0.12 12.5 0.2 1.7 1 0 0 1 1 1 0 outer-membrane spanin sub-unit Presenilin PF01080.17 CBK24967.2 - 1.1 8.0 5.3 2.2 6.9 0.5 2.1 2 0 0 2 2 2 0 Presenilin AMP-binding PF00501.28 CBK24968.2 - 8.9e-08 31.1 0.0 1.2e-07 30.7 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme TraG_N PF07916.11 CBK24969.2 - 0.073 11.9 0.1 0.079 11.8 0.1 1.0 1 0 0 1 1 1 0 TraG-like protein, N-terminal region TMEM141 PF15110.6 CBK24969.2 - 0.17 12.5 0.4 4.1 8.1 0.1 2.2 2 0 0 2 2 2 0 TMEM141 protein family PUF PF00806.19 CBK24970.2 - 3.8e-20 70.4 10.6 0.0038 16.8 0.0 8.0 8 0 0 8 8 8 5 Pumilio-family RNA binding repeat Cbl_N3 PF02762.14 CBK24970.2 - 0.028 14.3 0.0 0.18 11.7 0.0 2.4 2 0 0 2 2 2 0 CBL proto-oncogene N-terminus, SH2-like domain FbpA PF05833.11 CBK24970.2 - 0.06 12.1 0.0 0.091 11.5 0.0 1.2 1 0 0 1 1 1 0 Fibronectin-binding protein A N-terminus (FbpA) ACDC PF14733.6 CBK24970.2 - 0.1 12.9 0.0 3.6 8.0 0.0 3.0 3 0 0 3 3 3 0 AP2-coincident C-terminal ATG16 PF08614.11 CBK24971.2 - 0.00058 20.1 18.2 0.0036 17.6 9.4 2.1 1 1 1 2 2 2 2 Autophagy protein 16 (ATG16) ZapB PF06005.12 CBK24971.2 - 0.00073 19.9 26.3 0.42 11.1 2.7 3.2 2 1 1 3 3 3 3 Cell division protein ZapB bZIP_1 PF00170.21 CBK24971.2 - 0.00082 19.4 21.9 0.01 15.9 1.9 3.5 3 1 0 3 3 3 2 bZIP transcription factor KASH_CCD PF14662.6 CBK24971.2 - 0.00082 19.2 23.8 0.037 13.9 13.9 2.8 2 1 0 2 2 2 2 Coiled-coil region of CCDC155 or KASH GAS PF13851.6 CBK24971.2 - 0.0039 16.6 21.2 0.068 12.5 11.9 2.3 1 1 1 2 2 2 2 Growth-arrest specific micro-tubule binding GIT_CC PF16559.5 CBK24971.2 - 0.0054 16.6 15.2 0.22 11.4 3.1 3.4 2 1 1 3 3 3 2 GIT coiled-coil Rho guanine nucleotide exchange factor DASH_Spc19 PF08287.11 CBK24971.2 - 0.012 15.6 18.1 0.38 10.6 2.0 2.6 1 1 1 2 2 2 0 Spc19 Prefoldin_2 PF01920.20 CBK24971.2 - 0.015 15.2 8.2 0.015 15.2 8.2 2.3 1 1 1 2 2 2 0 Prefoldin subunit YabA PF06156.13 CBK24971.2 - 0.028 15.0 20.1 0.28 11.8 1.4 3.1 1 1 1 2 2 2 0 Initiation control protein YabA TSC22 PF01166.18 CBK24971.2 - 0.032 14.6 1.1 0.032 14.6 1.1 3.8 2 1 1 3 3 3 0 TSC-22/dip/bun family Herpes_BLRF2 PF05812.12 CBK24971.2 - 0.034 14.3 8.6 0.12 12.5 0.7 2.5 2 1 0 2 2 2 0 Herpesvirus BLRF2 protein TPR_MLP1_2 PF07926.12 CBK24971.2 - 0.039 14.0 22.3 0.47 10.5 10.6 2.6 2 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein CENP-F_leu_zip PF10473.9 CBK24971.2 - 0.044 13.8 26.6 0.77 9.8 12.3 2.2 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 PRKG1_interact PF15898.5 CBK24971.2 - 0.05 14.5 18.0 0.2 12.6 18.0 2.0 1 1 0 1 1 1 0 cGMP-dependent protein kinase interacting domain tRNA-synt_2c PF01411.19 CBK24971.2 - 0.065 11.7 6.5 0.085 11.4 6.5 1.1 1 0 0 1 1 1 0 tRNA synthetases class II (A) Jnk-SapK_ap_N PF09744.9 CBK24971.2 - 0.074 13.3 17.7 0.63 10.3 8.1 2.2 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 DUF4201 PF13870.6 CBK24971.2 - 0.079 12.7 19.2 0.75 9.5 12.8 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) HOOK PF05622.12 CBK24971.2 - 0.086 11.0 19.8 0.21 9.7 19.8 1.6 1 1 0 1 1 1 0 HOOK protein CCDC144C PF14915.6 CBK24971.2 - 0.1 11.7 20.2 0.14 11.2 0.6 2.4 2 1 0 2 2 2 0 CCDC144C protein coiled-coil region Filament PF00038.21 CBK24971.2 - 0.1 12.2 21.4 2 7.9 21.3 2.4 1 1 0 1 1 1 0 Intermediate filament protein DivIC PF04977.15 CBK24971.2 - 0.1 12.4 18.1 1.8 8.4 1.4 3.3 2 1 1 3 3 3 0 Septum formation initiator ADIP PF11559.8 CBK24971.2 - 0.11 12.5 19.7 0.31 11.1 9.7 2.4 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding Mod_r PF07200.13 CBK24971.2 - 0.12 12.5 25.1 0.41 10.7 23.6 2.4 2 1 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein T3SSipB PF16535.5 CBK24971.2 - 0.12 12.8 9.6 0.84 10.1 9.6 2.0 1 1 0 1 1 1 0 Type III cell invasion protein SipB Cnn_1N PF07989.11 CBK24971.2 - 0.13 12.4 22.2 2.2e+02 2.1 19.2 3.1 2 1 0 2 2 2 0 Centrosomin N-terminal motif 1 PRP1_N PF06424.12 CBK24971.2 - 0.14 12.5 6.5 0.25 11.7 5.7 1.8 1 1 0 1 1 1 0 PRP1 splicing factor, N-terminal TMF_TATA_bd PF12325.8 CBK24971.2 - 0.16 12.2 22.7 1.2 9.4 8.9 3.0 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding Syntaxin PF00804.25 CBK24971.2 - 0.18 11.5 11.6 1.8 8.2 3.5 2.2 2 0 0 2 2 2 0 Syntaxin LMBR1 PF04791.16 CBK24971.2 - 0.23 10.3 4.0 0.22 10.4 4.0 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein BLOC1_2 PF10046.9 CBK24971.2 - 0.26 11.6 16.1 2.7 8.3 0.2 2.6 2 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF1664 PF07889.12 CBK24971.2 - 0.28 11.2 10.2 1.8 8.6 4.1 2.6 1 1 1 3 3 3 0 Protein of unknown function (DUF1664) Misat_Tub_SegII PF10644.9 CBK24971.2 - 0.35 11.2 6.8 0.12 12.7 0.5 2.3 1 1 1 2 2 2 0 Misato Segment II tubulin-like domain Ax_dynein_light PF10211.9 CBK24971.2 - 0.37 10.7 20.5 0.48 10.3 4.5 2.4 1 1 1 2 2 2 0 Axonemal dynein light chain ERM PF00769.19 CBK24971.2 - 0.37 10.6 20.6 1.6 8.5 20.6 1.8 1 1 0 1 1 1 0 Ezrin/radixin/moesin family SlyX PF04102.12 CBK24971.2 - 0.38 11.4 11.7 11 6.7 0.4 3.5 1 1 2 3 3 3 0 SlyX SKA1 PF07160.12 CBK24971.2 - 0.46 10.3 11.6 0.78 9.5 11.6 1.3 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 1 CSN7a_helixI PF18392.1 CBK24971.2 - 0.49 10.3 3.2 0.38 10.7 0.7 2.0 2 0 0 2 2 2 0 COP9 signalosome complex subunit 7a helix I domain Spc7 PF08317.11 CBK24971.2 - 0.6 8.9 21.9 0.38 9.6 10.6 2.0 1 1 1 2 2 2 0 Spc7 kinetochore protein ParB PF08775.10 CBK24971.2 - 0.68 10.4 7.6 0.4 11.2 3.2 2.1 2 0 0 2 2 2 0 ParB family DUF4337 PF14235.6 CBK24971.2 - 0.74 9.9 11.8 0.54 10.4 0.4 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4337) bZIP_Maf PF03131.17 CBK24971.2 - 0.77 10.3 14.9 0.88 10.1 0.7 3.3 2 1 1 3 3 3 0 bZIP Maf transcription factor COG2 PF06148.11 CBK24971.2 - 0.85 9.7 14.8 0.79 9.8 6.3 2.7 2 1 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Taxilin PF09728.9 CBK24971.2 - 0.88 8.7 22.6 15 4.7 22.6 2.1 1 1 0 1 1 1 0 Myosin-like coiled-coil protein HALZ PF02183.18 CBK24971.2 - 1.1 9.6 16.9 1.6 9.0 2.3 4.3 4 2 0 4 4 3 0 Homeobox associated leucine zipper Cep57_CLD_2 PF14197.6 CBK24971.2 - 1.1 9.4 20.4 1.1 9.4 2.9 3.0 2 1 0 2 2 2 0 Centrosome localisation domain of PPC89 MapZ_EC1 PF18041.1 CBK24971.2 - 1.2 9.4 11.1 0.42 10.9 2.4 2.3 1 1 0 2 2 2 0 MapZ extracellular domain 1 Fib_alpha PF08702.10 CBK24971.2 - 1.2 9.3 16.3 1.2 9.3 8.7 2.2 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Mto2_bdg PF12808.7 CBK24971.2 - 1.2 9.4 7.9 1.4 9.2 1.6 2.8 2 1 0 2 2 2 0 Micro-tubular organiser Mto1 C-term Mto2-binding region TolA_bind_tri PF16331.5 CBK24971.2 - 1.3 9.1 13.3 6.9 6.8 0.1 2.4 2 0 0 2 2 2 0 TolA binding protein trimerisation Seryl_tRNA_N PF02403.22 CBK24971.2 - 1.6 9.0 14.3 10 6.4 6.7 2.4 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Wtap PF17098.5 CBK24971.2 - 1.6 8.7 20.3 0.13 12.2 3.2 2.5 1 1 0 2 2 2 0 WTAP/Mum2p family DASH_Dam1 PF08653.10 CBK24971.2 - 1.6 8.6 6.8 14 5.6 1.2 3.3 3 1 0 3 3 3 0 DASH complex subunit Dam1 DUF3450 PF11932.8 CBK24971.2 - 1.7 7.9 18.4 4.3 6.6 11.9 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) FapA PF03961.13 CBK24971.2 - 1.8 7.1 15.8 0.5 8.9 4.4 2.0 1 1 1 2 2 2 0 Flagellar Assembly Protein A RNase_E_G PF10150.9 CBK24971.2 - 1.8 7.9 9.3 0.91 8.9 6.1 1.8 1 1 1 2 2 2 0 Ribonuclease E/G family TMPIT PF07851.13 CBK24971.2 - 1.8 7.7 17.5 0.39 9.9 9.0 2.0 1 1 0 2 2 2 0 TMPIT-like protein FPP PF05911.11 CBK24971.2 - 2 6.5 23.6 4.7 5.3 23.6 1.5 1 1 0 1 1 1 0 Filament-like plant protein, long coiled-coil Lebercilin PF15619.6 CBK24971.2 - 2.1 8.0 19.9 1.4 8.6 2.1 2.3 1 1 1 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease IFT57 PF10498.9 CBK24971.2 - 2.1 7.2 19.3 14 4.5 10.4 2.3 1 1 1 2 2 2 0 Intra-flagellar transport protein 57 DUF5320 PF17253.2 CBK24971.2 - 2.1 9.4 10.7 0.57 11.3 1.6 2.9 2 2 1 3 3 2 0 Family of unknown function (DUF5320) Exonuc_VII_L PF02601.15 CBK24971.2 - 2.2 7.8 11.4 2.8 7.4 11.4 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit LPP PF04728.13 CBK24971.2 - 2.7 8.5 16.9 1.6 9.2 0.3 4.2 3 1 2 5 5 4 0 Lipoprotein leucine-zipper zf-C4H2 PF10146.9 CBK24971.2 - 2.8 8.2 18.2 0.35 11.2 8.7 2.0 1 1 1 2 2 2 0 Zinc finger-containing protein UPF0242 PF06785.11 CBK24971.2 - 2.9 8.0 24.9 3.5 7.7 14.5 2.2 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Swi5 PF07061.11 CBK24971.2 - 3.4 7.8 17.1 2 8.5 1.1 3.2 2 1 1 3 3 3 0 Swi5 Rootletin PF15035.6 CBK24971.2 - 3.6 7.6 20.7 6.7 6.7 10.7 2.5 1 1 1 2 2 2 0 Ciliary rootlet component, centrosome cohesion MctB PF11382.8 CBK24971.2 - 4.3 7.0 7.4 0.97 9.1 0.3 2.4 1 1 2 3 3 2 0 Copper transport outer membrane protein, MctB FlaC_arch PF05377.11 CBK24971.2 - 4.5 7.7 22.0 0.45 11.0 1.7 3.7 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) Atg14 PF10186.9 CBK24971.2 - 5 6.1 17.7 66 2.4 17.7 2.1 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 CENP-H PF05837.12 CBK24971.2 - 5.5 7.4 14.7 3 8.3 5.4 2.3 2 0 0 2 2 2 0 Centromere protein H (CENP-H) MCU PF04678.13 CBK24971.2 - 6 6.9 11.2 2.4 8.2 2.8 2.2 1 1 1 2 2 2 0 Mitochondrial calcium uniporter Shugoshin_N PF07558.11 CBK24971.2 - 6 6.8 16.9 0.62 10.0 0.5 3.5 2 1 2 4 4 3 0 Shugoshin N-terminal coiled-coil region TSNAXIP1_N PF15739.5 CBK24971.2 - 8.2 6.8 16.5 7.9 6.9 1.9 2.4 1 1 1 2 2 2 0 Translin-associated factor X-interacting N-terminus DUF4407 PF14362.6 CBK24971.2 - 9 5.5 9.0 80 2.4 9.0 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Spc7 PF08317.11 CBK24972.2 - 0.00012 21.0 27.7 0.00012 21.0 27.7 3.1 2 1 1 3 3 3 1 Spc7 kinetochore protein DivIC PF04977.15 CBK24972.2 - 0.002 17.9 4.3 0.002 17.9 4.3 6.5 2 2 3 7 7 7 1 Septum formation initiator TMF_TATA_bd PF12325.8 CBK24972.2 - 0.14 12.4 56.2 0.31 11.3 17.3 5.0 2 1 3 5 5 5 0 TATA element modulatory factor 1 TATA binding Cortex-I_coil PF09304.10 CBK24972.2 - 0.24 11.6 50.0 0.098 12.9 11.4 4.2 1 1 2 4 4 4 0 Cortexillin I, coiled coil THOC7 PF05615.13 CBK24972.2 - 0.53 10.6 52.8 0.064 13.5 17.3 4.1 2 1 2 4 4 4 0 Tho complex subunit 7 DUF4407 PF14362.6 CBK24972.2 - 1.6 8.0 37.4 0.044 13.1 20.1 2.7 1 1 2 3 3 3 0 Domain of unknown function (DUF4407) DUF3450 PF11932.8 CBK24972.2 - 3.1 7.0 55.3 1.5 8.1 9.0 4.1 2 1 2 4 4 4 0 Protein of unknown function (DUF3450) ATG16 PF08614.11 CBK24972.2 - 3.2 7.9 64.6 11 6.2 29.2 3.6 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) CEP209_CC5 PF16574.5 CBK24972.2 - 3.5 7.8 37.4 0.058 13.6 17.5 4.1 2 1 2 4 4 4 0 Coiled-coil region of centrosome protein CE290 SLATT_6 PF18169.1 CBK24972.2 - 4.3 6.9 8.5 0.32 10.6 1.0 2.7 1 1 2 3 3 3 0 SMODS and SLOG-associating 2TM effector domain 6 Tho2 PF11262.8 CBK24972.2 - 5.5 6.1 28.3 3.7 6.7 11.5 2.7 1 1 1 2 2 2 0 Transcription factor/nuclear export subunit protein 2 BRE1 PF08647.11 CBK24972.2 - 6.3 7.0 57.5 0.24 11.5 16.9 4.2 3 2 1 4 4 4 0 BRE1 E3 ubiquitin ligase Troponin PF00992.20 CBK24972.2 - 6.4 7.1 41.2 0.89 9.9 12.7 4.4 1 1 3 4 4 4 0 Troponin DUF1664 PF07889.12 CBK24972.2 - 6.8 6.7 34.5 8.9 6.4 7.6 4.1 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) APG6_N PF17675.1 CBK24972.2 - 7.1 7.2 73.7 0.47 11.0 12.4 5.1 2 1 3 5 5 5 0 Apg6 coiled-coil region ERM PF00769.19 CBK24972.2 - 9.9 5.9 62.6 0.99 9.2 18.5 3.8 1 1 2 3 3 3 0 Ezrin/radixin/moesin family ATG16 PF08614.11 CBK24973.2 - 0.00076 19.8 54.9 0.0016 18.7 14.7 3.2 2 1 1 3 3 3 2 Autophagy protein 16 (ATG16) DUF2959 PF11172.8 CBK24973.2 - 0.0038 17.4 0.8 0.0038 17.4 0.8 3.4 2 2 1 3 3 3 1 Protein of unknown function (DUF2959) CENP-F_leu_zip PF10473.9 CBK24973.2 - 0.0088 16.1 45.3 0.44 10.6 11.1 4.7 1 1 2 3 3 3 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 FliJ PF02050.16 CBK24973.2 - 0.024 14.8 1.1 0.024 14.8 1.1 4.1 2 2 1 4 4 4 0 Flagellar FliJ protein Hc1 PF07432.13 CBK24973.2 - 0.035 14.5 4.0 0.035 14.5 4.0 3.2 4 0 0 4 4 4 0 Histone H1-like protein Hc1 FapA PF03961.13 CBK24973.2 - 0.12 11.0 21.8 0.15 10.6 0.6 2.7 1 1 1 2 2 2 0 Flagellar Assembly Protein A Golgin_A5 PF09787.9 CBK24973.2 - 0.19 11.1 45.1 0.3 10.5 19.3 3.1 1 1 2 3 3 3 0 Golgin subfamily A member 5 DUF4407 PF14362.6 CBK24973.2 - 0.6 9.4 37.3 0.61 9.4 21.9 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) Fez1 PF06818.15 CBK24973.2 - 1.1 9.7 41.9 0.59 10.5 10.1 2.5 1 1 1 2 2 2 0 Fez1 Fib_alpha PF08702.10 CBK24973.2 - 1.8 8.7 20.8 0.059 13.5 3.5 3.3 2 2 1 3 3 3 0 Fibrinogen alpha/beta chain family Spc7 PF08317.11 CBK24973.2 - 2 7.2 47.4 2.6 6.8 12.3 3.3 1 1 2 3 3 3 0 Spc7 kinetochore protein HIP1_clath_bdg PF16515.5 CBK24973.2 - 3.2 8.4 49.4 2.6 8.7 2.2 5.1 2 2 2 5 5 5 0 Clathrin-binding domain of Huntingtin-interacting protein 1 MscS_porin PF12795.7 CBK24973.2 - 3.8 7.0 53.1 0.16 11.5 26.8 3.2 1 1 3 4 4 4 0 Mechanosensitive ion channel porin domain CALCOCO1 PF07888.11 CBK24973.2 - 4.7 6.0 51.7 0.52 9.1 9.1 2.8 2 1 0 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like HOOK PF05622.12 CBK24973.2 - 7.7 4.5 39.6 42 2.1 38.0 2.1 1 1 0 1 1 1 0 HOOK protein Atrophin-1 PF03154.15 CBK24974.2 - 1.7 6.8 10.6 2.1 6.5 10.6 1.2 1 0 0 1 1 1 0 Atrophin-1 family SAC3_GANP PF03399.16 CBK24975.2 - 2.3e-22 79.7 7.2 2.4e-21 76.4 7.2 1.9 1 1 0 1 1 1 1 SAC3/GANP family CSN8_PSD8_EIF3K PF10075.9 CBK24975.2 - 0.00069 19.6 0.1 0.0094 15.9 0.1 2.2 1 1 0 1 1 1 1 CSN8/PSMD8/EIF3K family mRNA_cap_enzyme PF01331.19 CBK24977.2 - 1.1e-16 61.2 0.0 1.3e-16 61.0 0.0 1.0 1 0 0 1 1 1 1 mRNA capping enzyme, catalytic domain DNA_ligase_A_M PF01068.21 CBK24977.2 - 9.2e-05 22.2 0.0 0.00013 21.7 0.0 1.3 1 0 0 1 1 1 1 ATP dependent DNA ligase domain RICTOR_N PF14664.6 CBK24979.2 - 1.1e-68 231.9 16.7 2e-68 231.1 16.7 1.4 1 0 0 1 1 1 1 Rapamycin-insensitive companion of mTOR, N-term RICTOR_V PF14668.6 CBK24979.2 - 6.2e-18 64.8 0.0 4.9e-17 61.9 0.0 2.7 3 0 0 3 3 3 1 Rapamycin-insensitive companion of mTOR, domain 5 RasGEF_N_2 PF14663.6 CBK24979.2 - 9.9e-05 22.7 0.0 0.0004 20.7 0.0 2.1 1 0 0 1 1 1 1 Rapamycin-insensitive companion of mTOR RasGEF_N domain DUF762 PF05555.11 CBK24979.2 - 0.019 14.5 0.0 0.058 13.0 0.0 1.8 1 0 0 1 1 1 0 Coxiella burnetii protein of unknown function (DUF762) RICTOR_M PF14666.6 CBK24979.2 - 0.083 12.7 2.8 0.41 10.5 0.1 3.3 3 0 0 3 3 3 0 Rapamycin-insensitive companion of mTOR, middle domain HSP70 PF00012.20 CBK24982.2 - 1.6e-17 63.0 0.0 2.1e-17 62.6 0.0 1.1 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 CBK24982.2 - 0.0032 16.3 0.1 0.3 9.9 0.0 2.1 2 0 0 2 2 2 2 MreB/Mbl protein HSP70 PF00012.20 CBK24983.2 - 5.8e-09 34.7 0.0 6.5e-09 34.5 0.0 1.0 1 0 0 1 1 1 1 Hsp70 protein Nicastrin PF05450.15 CBK24984.2 - 0.029 13.9 0.0 0.04 13.4 0.0 1.2 1 0 0 1 1 1 0 Nicastrin Peptidase_M28 PF04389.17 CBK24984.2 - 0.12 12.1 0.0 0.16 11.6 0.0 1.2 1 0 0 1 1 1 0 Peptidase family M28 Aldolase_II PF00596.21 CBK24986.2 - 1.1e-30 106.9 0.1 7.9e-24 84.6 0.0 2.2 1 1 1 2 2 2 2 Class II Aldolase and Adducin N-terminal domain SRP54 PF00448.22 CBK24988.2 - 9.9e-77 257.0 0.1 2.1e-76 255.9 0.1 1.6 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SRP_SPB PF02978.19 CBK24988.2 - 1.6e-22 79.9 4.0 1.6e-22 79.9 4.0 3.1 3 0 0 3 3 3 1 Signal peptide binding domain SRP54_N PF02881.19 CBK24988.2 - 6e-18 64.8 1.7 1.5e-17 63.6 1.7 1.7 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain cobW PF02492.19 CBK24988.2 - 8e-05 22.3 0.8 0.0011 18.6 0.4 2.8 2 1 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain SRPRB PF09439.10 CBK24988.2 - 8.2e-05 22.1 0.8 0.029 13.8 0.1 2.6 1 1 0 2 2 2 2 Signal recognition particle receptor beta subunit AAA_16 PF13191.6 CBK24988.2 - 0.00024 21.5 0.0 0.00048 20.5 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_33 PF13671.6 CBK24988.2 - 0.0015 18.7 0.1 0.0043 17.2 0.0 1.9 2 0 0 2 2 1 1 AAA domain DUF2209 PF09974.9 CBK24988.2 - 0.0015 18.8 2.4 0.015 15.6 0.1 2.9 3 0 0 3 3 3 1 Uncharacterized protein conserved in archaea (DUF2209) MeaB PF03308.16 CBK24988.2 - 0.0023 16.9 0.0 0.0056 15.7 0.0 1.6 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_30 PF13604.6 CBK24988.2 - 0.0023 17.7 0.0 0.0053 16.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.23 CBK24988.2 - 0.0052 16.8 0.3 0.048 13.8 0.3 2.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase CbiA PF01656.23 CBK24988.2 - 0.0054 16.8 0.0 0.019 15.0 0.0 2.0 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain Zeta_toxin PF06414.12 CBK24988.2 - 0.0096 15.2 0.0 0.056 12.7 0.0 2.2 2 0 0 2 2 2 1 Zeta toxin ResIII PF04851.15 CBK24988.2 - 0.011 15.7 0.8 0.052 13.5 0.8 1.9 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_19 PF13245.6 CBK24988.2 - 0.019 15.3 0.0 0.048 14.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain APS_kinase PF01583.20 CBK24988.2 - 0.021 14.7 0.0 0.1 12.5 0.0 2.1 2 0 0 2 2 2 0 Adenylylsulphate kinase MobB PF03205.14 CBK24988.2 - 0.028 14.3 0.0 0.07 13.0 0.0 1.7 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_22 PF13401.6 CBK24988.2 - 0.057 13.7 0.0 0.21 11.9 0.0 2.0 1 0 0 1 1 1 0 AAA domain T3SS_needle_reg PF09025.10 CBK24988.2 - 0.073 13.0 0.1 0.21 11.6 0.1 1.8 2 0 0 2 2 1 0 YopR, type III needle-polymerisation regulator AAA_28 PF13521.6 CBK24988.2 - 0.1 12.8 0.0 0.39 10.9 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.6 CBK24988.2 - 2.5 8.5 10.1 0.28 11.6 1.0 3.6 3 1 0 3 3 3 0 AAA domain IFRD PF05004.13 CBK24989.2 - 2.4e-21 76.2 8.4 3.2e-21 75.7 8.4 1.0 1 0 0 1 1 1 1 Interferon-related developmental regulator (IFRD) TAN PF11640.8 CBK24989.2 - 0.00042 20.5 1.5 0.0058 16.8 0.2 2.3 2 0 0 2 2 2 1 Telomere-length maintenance and DNA damage repair Apyrase PF06079.11 CBK24990.2 - 8e-122 406.0 2.2 1e-121 405.7 2.2 1.1 1 0 0 1 1 1 1 Apyrase CFIA_Pcf11 PF11526.8 CBK24990.2 - 0.07 13.6 1.1 2.2 8.8 0.0 2.4 2 0 0 2 2 2 0 Subunit of cleavage factor IA Pcf11 LSM PF01423.22 CBK24991.2 - 6.4e-20 70.6 5.5 7.9e-20 70.3 5.5 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 CBK24991.2 - 6.5e-06 26.2 0.3 8.6e-06 25.8 0.3 1.3 1 0 0 1 1 1 1 Ataxin 2 SM domain HLH PF00010.26 CBK24993.2 - 0.0028 17.6 0.3 0.0069 16.3 0.3 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain CemA PF03040.14 CBK24993.2 - 0.1 12.5 0.1 0.16 11.9 0.1 1.3 1 0 0 1 1 1 0 CemA family Metallophos PF00149.28 CBK24994.2 - 1.2e-32 114.1 0.1 1.6e-32 113.7 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 CBK24994.2 - 0.0036 17.5 0.0 0.0057 16.9 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain STPPase_N PF16891.5 CBK24994.2 - 0.01 16.3 0.0 0.019 15.4 0.0 1.4 1 0 0 1 1 1 0 Serine-threonine protein phosphatase N-terminal domain Ribosomal_L2_C PF03947.18 CBK24995.2 - 1.4e-45 154.6 1.6 2.1e-45 154.0 1.6 1.2 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 CBK24995.2 - 1.2e-14 54.0 0.1 3.4e-14 52.6 0.0 1.9 2 0 0 2 2 2 1 Ribosomal Proteins L2, RNA binding domain Presenilin PF01080.17 CBK24996.2 - 1.8e-87 293.7 25.6 1.2e-61 208.7 14.5 2.0 2 0 0 2 2 2 2 Presenilin T2SSF PF00482.23 CBK24996.2 - 0.31 11.0 4.9 1.8 8.6 0.7 2.4 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein F Cyclin_N PF00134.23 CBK24997.2 - 8.6e-09 35.2 1.0 1.5e-08 34.4 1.0 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain APA3_viroporin PF11289.8 CBK24998.2 - 0.14 11.7 0.5 0.19 11.3 0.5 1.1 1 0 0 1 1 1 0 Coronavirus accessory protein 3a BATS PF06968.13 CBK24999.2 - 0.01 15.9 0.0 0.02 15.1 0.0 1.5 1 1 0 1 1 1 0 Biotin and Thiamin Synthesis associated domain Ribosomal_L18A PF01775.17 CBK25000.2 - 2e-41 140.9 0.3 2.9e-41 140.4 0.3 1.2 1 0 0 1 1 1 1 Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A Ldh_1_N PF00056.23 CBK25001.2 - 4.5e-38 130.5 0.0 1e-37 129.4 0.0 1.6 2 0 0 2 2 2 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.18 CBK25001.2 - 1.1e-36 126.3 0.0 1.4e-36 125.9 0.0 1.1 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain THF_DHG_CYH_C PF02882.19 CBK25001.2 - 0.01 15.1 0.0 0.049 13.0 0.0 2.1 1 1 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Semialdhyde_dh PF01118.24 CBK25001.2 - 0.016 15.7 0.1 0.042 14.3 0.0 1.8 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain 3Beta_HSD PF01073.19 CBK25001.2 - 0.034 13.1 0.0 0.068 12.2 0.0 1.5 2 0 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family Glyco_hydro_4 PF02056.16 CBK25001.2 - 0.062 12.8 0.0 0.29 10.7 0.0 2.1 2 0 0 2 2 2 0 Family 4 glycosyl hydrolase zf-AN1 PF01428.16 CBK25002.2 - 1.6e-18 66.6 26.6 4.4e-11 42.8 8.1 3.1 3 0 0 3 3 3 2 AN1-like Zinc finger Transp_Tc5_C PF04236.15 CBK25002.2 - 0.001 19.3 25.1 0.0017 18.7 6.1 3.1 2 1 1 3 3 3 2 Tc5 transposase C-terminal domain IBR PF01485.21 CBK25002.2 - 0.014 15.6 7.7 0.014 15.6 7.7 3.2 1 1 2 3 3 3 0 IBR domain, a half RING-finger domain zf-C3HC PF07967.13 CBK25002.2 - 0.15 12.1 14.3 0.11 12.5 1.9 3.0 1 1 1 3 3 3 0 C3HC zinc finger-like FYVE PF01363.21 CBK25002.2 - 0.18 12.0 18.7 0.16 12.2 5.0 2.3 2 0 0 2 2 2 0 FYVE zinc finger DZR PF12773.7 CBK25002.2 - 2.3 8.3 15.8 1.3e+02 2.7 15.8 3.0 1 1 0 1 1 1 0 Double zinc ribbon Thioredoxin_7 PF13899.6 CBK25003.2 - 0.087 13.0 0.0 0.22 11.7 0.0 1.7 1 0 0 1 1 1 0 Thioredoxin-like HATPase_c_3 PF13589.6 CBK25004.2 - 7.3e-14 51.8 0.1 1.4e-13 50.8 0.0 1.5 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 CBK25004.2 - 3.7e-09 37.1 0.0 5.5e-09 36.5 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Rhabdo_glycop PF00974.18 CBK25004.2 - 0.0001 20.9 0.0 0.25 9.7 0.0 2.1 2 0 0 2 2 2 2 Rhabdovirus spike glycoprotein HATPase_c_5 PF14501.6 CBK25004.2 - 0.00055 19.8 0.2 0.001 19.0 0.2 1.4 1 0 0 1 1 1 1 GHKL domain ubiquitin PF00240.23 CBK25005.2 - 2.8e-34 116.7 0.5 5.8e-34 115.7 0.5 1.5 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_S27 PF01599.19 CBK25005.2 - 6.1e-25 87.1 2.4 1.6e-24 85.8 2.4 1.8 1 0 0 1 1 1 1 Ribosomal protein S27a Rad60-SLD PF11976.8 CBK25005.2 - 1.6e-15 56.6 0.6 1.6e-15 56.6 0.6 1.7 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 CBK25005.2 - 3.2e-05 24.3 0.7 0.00011 22.5 0.1 2.1 2 1 0 2 2 2 1 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 CBK25005.2 - 0.00039 20.5 0.9 0.00086 19.4 0.9 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 CBK25005.2 - 0.0019 18.7 0.6 0.0028 18.2 0.6 1.2 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain TBK1_ULD PF18396.1 CBK25005.2 - 0.0079 16.1 0.1 0.013 15.4 0.1 1.4 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain Ubiquitin_5 PF18037.1 CBK25005.2 - 0.018 15.4 0.1 0.018 15.4 0.1 2.0 1 1 1 2 2 2 0 Ubiquitin-like domain Ubiquitin_4 PF18036.1 CBK25005.2 - 0.025 14.6 1.1 6.7 6.8 0.2 2.5 2 0 0 2 2 2 0 Ubiquitin-like domain IBR PF01485.21 CBK25005.2 - 0.057 13.6 0.6 0.1 12.9 0.6 1.5 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain Plexin_cytopl PF08337.12 CBK25005.2 - 0.078 11.6 0.8 5.5 5.5 0.1 2.1 2 0 0 2 2 2 0 Plexin cytoplasmic RasGAP domain zf-ribbon_3 PF13248.6 CBK25005.2 - 6.1 6.4 6.9 60 3.2 6.9 2.2 1 1 0 1 1 1 0 zinc-ribbon domain HSP70 PF00012.20 CBK25006.2 - 6.6e-08 31.2 0.0 2.2e-07 29.5 0.0 1.7 1 1 0 1 1 1 1 Hsp70 protein Fra10Ac1 PF09725.9 CBK25006.2 - 0.053 13.6 0.8 0.093 12.8 0.8 1.4 1 1 0 1 1 1 0 Folate-sensitive fragile site protein Fra10Ac1 zf-RING_2 PF13639.6 CBK25007.2 - 2.7e-11 43.6 6.3 5.8e-11 42.5 6.3 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 CBK25007.2 - 1.8e-09 37.2 3.0 1.8e-09 37.2 3.0 1.9 2 0 0 2 2 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 CBK25007.2 - 8.5e-09 35.1 6.9 2.1e-08 33.9 6.9 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CBK25007.2 - 2.3e-08 33.8 4.9 4.7e-08 32.9 4.9 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.7 CBK25007.2 - 3.9e-08 33.5 8.9 2e-07 31.2 8.9 2.0 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_3 PF13920.6 CBK25007.2 - 3.4e-07 30.0 2.7 7.8e-07 28.9 2.7 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CBK25007.2 - 5.8e-07 29.3 7.9 1.3e-06 28.2 7.9 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CBK25007.2 - 1.3e-06 28.3 2.5 3.2e-06 27.1 2.5 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-ANAPC11 PF12861.7 CBK25007.2 - 2.3e-05 24.4 3.4 8.4e-05 22.6 3.4 1.9 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.6 CBK25007.2 - 0.00014 21.6 3.4 0.00034 20.4 3.4 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 Zn_ribbon_17 PF17120.5 CBK25007.2 - 0.00023 20.7 2.7 0.0005 19.6 2.7 1.5 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-RING_4 PF14570.6 CBK25007.2 - 0.00057 19.6 5.5 0.0012 18.5 5.5 1.6 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-C3H2C3 PF17122.5 CBK25007.2 - 0.022 14.8 5.9 0.091 12.8 5.0 2.5 2 0 0 2 2 2 0 Zinc-finger FANCL_C PF11793.8 CBK25007.2 - 0.045 13.9 5.7 0.16 12.1 5.7 2.0 1 1 0 1 1 1 0 FANCL C-terminal domain RINGv PF12906.7 CBK25007.2 - 0.064 13.4 5.3 0.14 12.3 5.3 1.6 1 0 0 1 1 1 0 RING-variant domain zf-RING-like PF08746.11 CBK25007.2 - 0.077 13.3 2.8 0.19 12.0 2.8 1.7 1 0 0 1 1 1 0 RING-like domain PHD PF00628.29 CBK25007.2 - 0.15 12.0 4.9 0.29 11.0 4.9 1.5 1 0 0 1 1 1 0 PHD-finger PHD PF00628.29 CBK25008.2 - 2.4e-09 37.0 6.9 6e-09 35.7 6.9 1.7 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 CBK25008.2 - 0.0013 18.3 4.0 0.0026 17.3 4.0 1.5 1 0 0 1 1 1 1 PHD-finger Sa_NUDIX PF18167.1 CBK25008.2 - 0.13 12.0 0.1 0.23 11.3 0.1 1.3 1 0 0 1 1 1 0 SMODS-associated NUDIX domain zf-H2C2_2 PF13465.6 CBK25008.2 - 1 9.9 3.0 15 6.2 0.7 2.6 2 0 0 2 2 2 0 Zinc-finger double domain zf-RING_2 PF13639.6 CBK25008.2 - 2.5 8.5 8.7 6.8 7.1 7.8 2.3 2 0 0 2 2 2 0 Ring finger domain Nipped-B_C PF12830.7 CBK25009.2 - 0.00042 20.3 0.0 0.0007 19.6 0.0 1.4 1 1 0 1 1 1 1 Sister chromatid cohesion C-terminus FAP PF07174.11 CBK25009.2 - 0.0091 15.5 11.7 0.01 15.3 11.7 1.1 1 0 0 1 1 1 1 Fibronectin-attachment protein (FAP) SPX PF03105.19 CBK25009.2 - 0.23 11.3 3.0 0.24 11.3 3.0 1.1 1 0 0 1 1 1 0 SPX domain Retinal PF15449.6 CBK25009.2 - 0.42 8.3 16.7 0.49 8.1 16.7 1.0 1 0 0 1 1 1 0 Retinal protein PA14 PF07691.12 CBK25010.2 - 0.00047 20.0 0.1 0.00095 19.0 0.1 1.6 1 0 0 1 1 1 1 PA14 domain He_PIG PF05345.12 CBK25010.2 - 0.00096 19.3 1.8 0.00096 19.3 1.8 3.7 3 1 0 3 3 3 1 Putative Ig domain GLEYA PF10528.9 CBK25010.2 - 0.0081 16.6 0.1 0.022 15.2 0.1 1.9 1 0 0 1 1 1 1 GLEYA domain He_PIG PF05345.12 CBK25011.2 - 1.9e-14 53.5 22.8 1.6e-05 24.9 1.6 5.1 4 0 0 4 4 4 3 Putative Ig domain PA14 PF07691.12 CBK25011.2 - 6.4e-11 42.3 0.1 5.8e-10 39.2 0.1 2.3 2 0 0 2 2 2 1 PA14 domain DUF11 PF01345.18 CBK25011.2 - 1.8e-06 28.1 0.0 0.18 12.2 0.0 5.4 3 2 2 5 5 5 2 Domain of unknown function DUF11 F5_F8_type_C PF00754.25 CBK25011.2 - 0.003 17.7 3.2 0.003 17.7 3.2 2.1 2 0 0 2 2 2 1 F5/8 type C domain DUF2207 PF09972.9 CBK25011.2 - 0.0042 15.9 0.5 0.008 15.0 0.5 1.3 1 0 0 1 1 1 1 Predicted membrane protein (DUF2207) SIT PF15330.6 CBK25011.2 - 0.13 12.7 0.7 0.29 11.6 0.7 1.5 1 0 0 1 1 1 0 SHP2-interacting transmembrane adaptor protein, SIT Pkinase PF00069.25 CBK25012.2 - 1.2e-81 273.9 0.0 2.3e-81 273.0 0.0 1.4 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBK25012.2 - 8e-40 136.7 0.0 1.2e-39 136.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PH PF00169.29 CBK25012.2 - 4.3e-08 33.6 0.4 7.9e-08 32.8 0.4 1.4 1 0 0 1 1 1 1 PH domain Kinase-like PF14531.6 CBK25012.2 - 9.2e-07 28.5 0.1 0.0012 18.3 0.0 2.7 1 1 1 2 2 2 2 Kinase-like Kdo PF06293.14 CBK25012.2 - 0.00022 20.7 0.0 0.00054 19.4 0.0 1.6 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CBK25012.2 - 0.012 15.5 0.0 0.19 11.6 0.0 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family PH_11 PF15413.6 CBK25012.2 - 0.018 15.5 0.5 0.054 13.9 0.5 1.8 1 0 0 1 1 1 0 Pleckstrin homology domain Choline_kinase PF01633.20 CBK25012.2 - 0.018 14.6 0.4 0.04 13.5 0.0 1.7 2 0 0 2 2 2 0 Choline/ethanolamine kinase RILP PF11461.8 CBK25012.2 - 0.019 15.2 0.1 0.045 14.0 0.1 1.6 1 0 0 1 1 1 0 Rab interacting lysosomal protein PH_3 PF14593.6 CBK25012.2 - 0.044 13.9 0.6 0.11 12.7 0.6 1.7 1 0 0 1 1 1 0 PH domain Haspin_kinase PF12330.8 CBK25012.2 - 0.083 11.8 0.0 0.14 11.1 0.0 1.4 1 0 0 1 1 1 0 Haspin like kinase domain PH PF00169.29 CBK25013.2 - 0.00039 20.9 0.2 0.0015 19.0 0.0 2.1 2 1 0 2 2 2 1 PH domain ANAPC4_WD40 PF12894.7 CBK25013.2 - 0.00062 20.0 0.0 0.78 10.1 0.0 3.3 3 1 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain NUP214 PF16755.5 CBK25013.2 - 0.045 13.0 0.0 0.068 12.4 0.0 1.2 1 0 0 1 1 1 0 Nucleoporin or Nuclear pore complex subunit NUP214=Nup159 PH_9 PF15410.6 CBK25013.2 - 0.056 13.8 0.1 0.21 12.0 0.0 2.0 1 1 0 1 1 1 0 Pleckstrin homology domain PQQ PF01011.21 CBK25013.2 - 0.17 11.9 2.2 2 8.5 0.1 3.4 3 0 0 3 3 3 0 PQQ enzyme repeat PQQ_3 PF13570.6 CBK25013.2 - 0.68 10.5 5.8 26 5.5 0.1 4.4 4 0 0 4 4 4 0 PQQ-like domain CENP-O PF09496.10 CBK25014.2 - 4.1e-13 49.8 0.1 9.5e-13 48.6 0.1 1.6 1 1 0 1 1 1 1 Cenp-O kinetochore centromere component zf-NOSIP PF15906.5 CBK25014.2 - 0.018 15.1 0.0 0.052 13.7 0.0 1.7 1 0 0 1 1 1 0 Zinc-finger of nitric oxide synthase-interacting protein TPR_2 PF07719.17 CBK25015.2 - 5.6e-10 38.6 0.0 1.6e-05 24.6 0.0 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.28 CBK25015.2 - 3.5e-09 36.1 0.0 1.9e-06 27.5 0.1 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 CBK25015.2 - 2.1e-08 33.7 0.1 0.00019 21.4 0.1 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.6 CBK25015.2 - 4.4e-06 26.9 0.0 8.3e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_17 PF13431.6 CBK25015.2 - 0.0011 19.2 1.9 0.046 14.1 0.0 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 CBK25015.2 - 0.0014 18.6 0.1 0.0047 17.0 0.0 1.9 2 0 0 2 2 2 1 Fis1 C-terminal tetratricopeptide repeat TPR_9 PF13371.6 CBK25015.2 - 0.0079 16.3 0.0 0.027 14.6 0.0 1.9 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_14 PF13428.6 CBK25015.2 - 0.011 16.5 0.0 2.9 9.0 0.0 2.7 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.6 CBK25015.2 - 0.032 14.2 0.0 1.5 9.1 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF3808 PF10300.9 CBK25015.2 - 0.04 12.7 0.0 0.066 12.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3808) Methyltransf_28 PF02636.17 CBK25015.2 - 0.059 13.0 0.0 0.12 12.0 0.0 1.7 1 1 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Sas10_Utp3 PF04000.15 CBK25017.2 - 1.5e-16 60.8 1.0 1.5e-16 60.8 1.0 2.0 2 0 0 2 2 2 1 Sas10/Utp3/C1D family V-SNARE_C PF12352.8 CBK25018.2 - 8.5e-11 42.0 1.1 1.2e-10 41.5 1.1 1.2 1 0 0 1 1 1 1 Snare region anchored in the vesicle membrane C-terminus kleA_kleC PF17383.2 CBK25018.2 - 0.19 12.1 3.5 0.19 12.1 0.6 2.0 1 1 1 2 2 2 0 Uncharacterized KorC regulated protein A Vac14_Fig4_bd PF11916.8 CBK25020.2 - 8.6e-17 61.4 0.1 2.1e-16 60.1 0.1 1.7 1 0 0 1 1 1 1 Vacuolar protein 14 C-terminal Fig4p binding Cnd1 PF12717.7 CBK25020.2 - 2.7e-05 24.2 5.7 0.038 14.0 2.1 3.4 1 1 1 2 2 2 2 non-SMC mitotic condensation complex subunit 1 Tti2 PF10521.9 CBK25020.2 - 0.00022 20.9 0.2 0.4 10.2 0.0 2.8 2 1 0 2 2 2 2 Tti2 family Vac14_Fab1_bd PF12755.7 CBK25020.2 - 0.0048 17.5 1.9 0.62 10.7 0.0 3.6 4 1 0 4 4 4 1 Vacuolar 14 Fab1-binding region ParcG PF10274.9 CBK25020.2 - 0.0098 16.0 3.3 0.047 13.8 1.8 2.5 2 1 1 3 3 3 1 Parkin co-regulated protein HEAT PF02985.22 CBK25020.2 - 0.033 14.5 1.7 66 4.2 0.0 5.2 6 0 0 6 6 6 0 HEAT repeat Dopey_N PF04118.14 CBK25020.2 - 0.038 13.1 0.3 0.038 13.1 0.3 3.1 2 2 2 4 4 4 0 Dopey, N-terminal DUF3425 PF11905.8 CBK25020.2 - 0.1 12.5 0.2 5.5 7.0 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3425) HEPN_SAV2148 PF18725.1 CBK25020.2 - 0.16 11.4 0.2 0.34 10.3 0.2 1.5 1 0 0 1 1 1 0 SAV2148-like HEPN V-ATPase_H_C PF11698.8 CBK25020.2 - 4.1 7.5 5.9 2.9 8.0 1.0 3.0 2 2 1 3 3 3 0 V-ATPase subunit H Vac14_Fab1_bd PF12755.7 CBK25021.2 - 1.2e-25 89.9 0.3 1.8e-25 89.3 0.3 1.3 1 0 0 1 1 1 1 Vacuolar 14 Fab1-binding region HEAT PF02985.22 CBK25021.2 - 2.1e-07 30.6 0.0 0.00014 21.8 0.0 3.3 4 0 0 4 4 4 1 HEAT repeat Adaptin_N PF01602.20 CBK25021.2 - 0.00071 18.3 0.0 0.00081 18.1 0.0 1.1 1 0 0 1 1 1 1 Adaptin N terminal region HEAT_EZ PF13513.6 CBK25021.2 - 0.0094 16.4 0.0 0.016 15.7 0.0 1.4 1 0 0 1 1 1 1 HEAT-like repeat Cnd1 PF12717.7 CBK25021.2 - 0.013 15.5 0.0 0.038 14.0 0.0 1.8 1 1 1 2 2 2 0 non-SMC mitotic condensation complex subunit 1 DRIM PF07539.12 CBK25021.2 - 0.023 13.0 0.0 0.024 12.9 0.0 1.1 1 0 0 1 1 1 0 Down-regulated in metastasis RTP1_C1 PF10363.9 CBK25021.2 - 0.024 14.8 0.0 0.047 13.9 0.0 1.5 1 0 0 1 1 1 0 Required for nuclear transport of RNA pol II C-terminus 1 Arm PF00514.23 CBK25021.2 - 0.024 14.7 0.0 12 6.1 0.0 2.6 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat PQ-loop PF04193.14 CBK25022.2 - 2e-21 75.5 1.2 4.3e-12 45.6 0.2 3.2 4 0 0 4 4 4 2 PQ loop repeat MtN3_slv PF03083.16 CBK25022.2 - 0.045 13.8 14.9 0.29 11.2 1.5 3.0 3 0 0 3 3 3 0 Sugar efflux transporter for intercellular exchange zf-U1 PF06220.12 CBK25023.2 - 6.6e-16 57.8 7.2 8.6e-16 57.4 7.2 1.2 1 0 0 1 1 1 1 U1 zinc finger zf-C2H2_jaz PF12171.8 CBK25023.2 - 0.04 14.2 7.9 0.74 10.2 7.9 2.4 1 1 0 1 1 1 0 Zinc-finger double-stranded RNA-binding Peptidase_C13 PF01650.18 CBK25024.2 - 2.4e-41 141.9 0.6 1.4e-40 139.5 0.0 1.9 2 0 0 2 2 2 1 Peptidase C13 family Acetyltransf_1 PF00583.25 CBK25025.2 - 4.4e-13 49.5 0.0 5.8e-13 49.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 CBK25025.2 - 2.5e-09 37.4 0.1 3.9e-09 36.8 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 CBK25025.2 - 1.2e-07 31.7 0.0 1.9e-07 31.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 CBK25025.2 - 0.0054 16.7 0.0 0.0095 15.9 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.6 CBK25025.2 - 0.011 15.8 0.0 0.022 14.9 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Acetyltransf_4 PF13420.7 CBK25025.2 - 0.046 13.9 0.1 0.052 13.7 0.1 1.1 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain PUF PF00806.19 CBK25025.2 - 0.094 12.5 0.0 0.19 11.5 0.0 1.5 1 0 0 1 1 1 0 Pumilio-family RNA binding repeat Acetyltransf_3 PF13302.7 CBK25025.2 - 0.17 12.5 0.0 0.21 12.2 0.0 1.1 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Ribosomal_S26e PF01283.19 CBK25026.2 - 1.7e-44 150.6 8.2 2e-44 150.5 8.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S26e Fer4_7 PF12838.7 CBK25026.2 - 0.00093 19.7 1.2 0.072 13.7 0.4 2.2 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_6 PF12837.7 CBK25026.2 - 0.0068 16.4 2.9 0.042 14.0 0.8 2.2 2 0 0 2 2 2 1 4Fe-4S binding domain SRP19 PF01922.17 CBK25026.2 - 0.007 17.3 0.2 0.0097 16.8 0.2 1.3 1 0 0 1 1 1 1 SRP19 protein RNA_pol_N PF01194.17 CBK25026.2 - 0.03 14.6 2.0 0.057 13.7 1.9 1.5 1 1 0 1 1 1 0 RNA polymerases N / 8 kDa subunit Fer4_2 PF12797.7 CBK25026.2 - 0.044 13.9 3.4 0.13 12.4 1.1 2.2 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4 PF00037.27 CBK25026.2 - 0.079 12.8 3.5 0.1 12.5 0.8 2.1 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_4 PF12800.7 CBK25026.2 - 0.87 10.3 7.3 0.63 10.7 2.6 2.2 2 0 0 2 2 2 0 4Fe-4S binding domain DLIC PF05783.11 CBK25027.2 - 4.8e-14 52.1 0.0 7.7e-14 51.4 0.0 1.3 1 1 0 1 1 1 1 Dynein light intermediate chain (DLIC) FANC_SAP PF18081.1 CBK25027.2 - 0.035 14.3 4.3 3.3 8.0 1.4 2.8 2 0 0 2 2 2 0 Fanconi anemia-associated nuclease SAP domain DUF4400 PF14348.6 CBK25027.2 - 0.28 10.7 1.4 0.64 9.5 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4400) partial_CstF PF15861.5 CBK25027.2 - 0.39 10.5 3.6 0.65 9.8 3.6 1.3 1 0 0 1 1 1 0 Partial cleavage stimulation factor domain JAB PF01398.21 CBK25028.2 - 1.4e-14 54.1 0.0 3.1e-14 53.0 0.0 1.6 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.6 CBK25028.2 - 6.9e-11 42.6 0.9 1.1e-10 41.9 0.9 1.4 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function Put_Phosphatase PF06888.12 CBK25028.2 - 0.035 13.5 0.2 0.053 12.9 0.2 1.3 1 0 0 1 1 1 0 Putative Phosphatase Nucleos_tra2_N PF01773.20 CBK25028.2 - 0.071 13.7 0.2 0.38 11.4 0.1 2.1 2 0 0 2 2 2 0 Na+ dependent nucleoside transporter N-terminus D123 PF07065.14 CBK25029.2 - 3.5e-11 42.8 0.5 3.5e-11 42.8 0.5 1.3 2 0 0 2 2 2 1 D123 DUF4439 PF14530.6 CBK25029.2 - 0.035 14.8 0.1 0.046 14.4 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4439) Rsc14 PF08586.10 CBK25029.2 - 0.23 12.3 5.2 0.19 12.6 0.5 2.1 1 1 1 2 2 2 0 RSC complex, Rsc14/Ldb7 subunit Keratin_B2_2 PF13885.6 CBK25030.2 - 1.7e-05 24.7 19.2 0.0018 18.2 4.1 4.1 1 1 3 4 4 4 3 Keratin, high sulfur B2 protein Vps36_ESCRT-II PF11605.8 CBK25030.2 - 0.08 13.1 0.0 0.13 12.4 0.0 1.2 1 0 0 1 1 1 0 Vacuolar protein sorting protein 36 Vps36 EF-hand_8 PF13833.6 CBK25031.2 - 7.9e-11 41.6 5.6 1.7e-08 34.2 0.7 3.1 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_7 PF13499.6 CBK25031.2 - 8.2e-11 42.2 6.2 1.3e-10 41.6 0.8 2.2 2 1 0 2 2 2 1 EF-hand domain pair EF-hand_9 PF14658.6 CBK25031.2 - 3.3e-08 33.7 0.2 3.1e-06 27.4 0.0 2.3 2 0 0 2 2 2 1 EF-hand domain EF-hand_6 PF13405.6 CBK25031.2 - 6.5e-08 31.9 4.1 0.022 14.7 0.0 3.9 4 0 0 4 4 4 2 EF-hand domain EF-hand_1 PF00036.32 CBK25031.2 - 1.8e-07 30.2 5.6 1.6e-05 24.1 1.9 3.9 4 0 0 4 4 4 1 EF hand SurA_N_2 PF13623.6 CBK25031.2 - 0.0012 18.8 1.8 0.067 13.1 0.1 2.6 2 1 1 3 3 3 1 SurA N-terminal domain EF-hand_14 PF17959.1 CBK25031.2 - 0.0012 19.1 1.7 0.061 13.7 0.1 2.7 2 1 0 2 2 2 1 EF-hand domain SurA_N_3 PF13624.6 CBK25031.2 - 0.011 15.6 1.2 0.13 12.1 0.1 2.2 2 1 0 2 2 2 0 SurA N-terminal domain EF-hand_10 PF14788.6 CBK25031.2 - 0.055 13.3 2.4 0.16 11.9 0.9 2.3 1 1 1 2 2 2 0 EF hand Cucumopine_C PF18631.1 CBK25031.2 - 0.079 12.9 0.2 0.33 10.9 0.1 2.0 1 1 0 2 2 2 0 Cucumopine synthase C-terminal helical bundle domain Dockerin_1 PF00404.18 CBK25031.2 - 0.08 13.1 0.0 0.25 11.6 0.0 1.8 2 0 0 2 2 2 0 Dockerin type I domain EF-hand_5 PF13202.6 CBK25031.2 - 0.094 12.3 1.1 0.094 12.3 1.1 3.3 4 0 0 4 4 4 0 EF hand RNA_pol_Rpc34 PF05158.12 CBK25032.2 - 3.3e-40 138.5 1.4 3.7e-40 138.3 1.4 1.0 1 0 0 1 1 1 1 RNA polymerase Rpc34 subunit RPA_C PF08784.11 CBK25032.2 - 0.067 13.9 0.1 0.12 13.0 0.0 1.4 1 1 0 1 1 1 0 Replication protein A C terminal DUF1653 PF07866.11 CBK25032.2 - 0.074 13.4 0.0 0.16 12.3 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1653) MarR_2 PF12802.7 CBK25032.2 - 0.16 11.9 0.0 0.3 11.0 0.0 1.4 1 0 0 1 1 1 0 MarR family Ribosomal_L39 PF00832.20 CBK25034.2 - 1.9e-17 62.6 9.4 2e-17 62.5 9.4 1.0 1 0 0 1 1 1 1 Ribosomal L39 protein Alpha-amylase PF00128.24 CBK25035.2 - 4.4e-12 46.2 0.0 2.4e-09 37.2 0.0 2.2 1 1 1 2 2 2 2 Alpha amylase, catalytic domain Alpha-amylase_C PF02806.18 CBK25035.2 - 5.5e-10 39.6 0.1 1.3e-09 38.4 0.1 1.6 1 0 0 1 1 1 1 Alpha amylase, C-terminal all-beta domain CBM_48 PF02922.18 CBK25036.2 - 9.1e-12 45.2 0.0 1.3e-11 44.7 0.0 1.2 1 0 0 1 1 1 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) SRP_SPB PF02978.19 CBK25037.2 - 2.6e-06 28.0 0.3 2.1e-05 25.1 0.0 2.1 2 0 0 2 2 2 1 Signal peptide binding domain DUF2153 PF09921.9 CBK25037.2 - 0.041 13.7 0.3 0.13 12.1 0.2 2.0 1 1 1 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2153) PIN_5 PF08745.11 CBK25037.2 - 0.042 13.3 0.3 0.2 11.1 0.0 1.8 1 1 1 2 2 2 0 PINc domain ribonuclease Sec1 PF00995.23 CBK25038.2 - 5.4e-14 52.3 0.0 5.9e-14 52.2 0.0 1.1 1 0 0 1 1 1 1 Sec1 family Sec1 PF00995.23 CBK25039.2 - 1.4e-31 110.4 0.3 1.7e-31 110.2 0.3 1.0 1 0 0 1 1 1 1 Sec1 family PX PF00787.24 CBK25040.2 - 1.2e-14 54.3 0.3 1.2e-14 54.3 0.3 2.5 3 0 0 3 3 3 1 PX domain Senescence PF06911.12 CBK25040.2 - 0.021 15.1 0.1 0.021 15.1 0.1 1.6 2 0 0 2 2 2 0 Senescence-associated protein DASH_Duo1 PF08651.10 CBK25040.2 - 0.096 12.5 6.7 4.7 7.1 0.0 3.7 3 1 0 3 3 3 0 DASH complex subunit Duo1 Phasin_2 PF09361.10 CBK25040.2 - 0.88 9.9 9.6 0.21 11.9 1.0 3.6 4 0 0 4 4 4 0 Phasin protein DUF948 PF06103.11 CBK25040.2 - 2.5 8.4 11.5 0.4 11.0 1.5 3.4 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) Cytomega_UL84 PF06284.11 CBK25040.2 - 3.9 5.8 10.6 5.9 5.2 10.6 1.2 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein Uteroglobin PF01099.17 CBK25040.2 - 4.7 7.6 6.8 0.91 9.9 1.0 2.8 3 1 0 3 3 3 0 Uteroglobin family WD40 PF00400.32 CBK25041.2 - 7.1e-47 156.4 18.6 1.2e-10 41.8 0.1 7.2 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBK25041.2 - 2.8e-10 40.4 4.3 0.0032 17.7 0.0 5.4 2 2 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 CBK25041.2 - 1.4e-06 27.3 7.3 0.015 14.0 0.1 5.0 3 1 2 5 5 5 3 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 CBK25041.2 - 9.3e-06 24.8 0.5 0.04 12.9 0.0 3.6 2 1 2 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein PQQ_2 PF13360.6 CBK25041.2 - 0.0064 16.1 1.7 0.083 12.5 0.0 2.3 2 1 0 2 2 2 1 PQQ-like domain DUF1513 PF07433.11 CBK25041.2 - 0.008 15.3 0.3 0.66 9.0 0.1 3.1 1 1 2 3 3 3 1 Protein of unknown function (DUF1513) Cytochrom_D1 PF02239.16 CBK25041.2 - 0.02 13.5 0.0 0.94 7.9 0.0 2.9 2 2 1 3 3 3 0 Cytochrome D1 heme domain PQQ_3 PF13570.6 CBK25041.2 - 0.085 13.4 0.7 18 6.0 0.1 3.8 3 1 0 3 3 3 0 PQQ-like domain SSXT PF05030.12 CBK25043.2 - 3.7e-05 23.3 0.2 4.4e-05 23.0 0.2 1.1 1 0 0 1 1 1 1 SSXT protein (N-terminal region) Glyco_transf_49 PF13896.6 CBK25044.2 - 5e-21 75.4 7.3 1.1e-16 61.1 3.9 2.4 1 1 1 2 2 2 2 Glycosyl-transferase for dystroglycan PKHD_C PF18331.1 CBK25044.2 - 0.15 12.1 0.1 0.36 10.9 0.1 1.6 1 0 0 1 1 1 0 PKHD-type hydroxylase C-terminal domain PyrI_C PF02748.15 CBK25044.2 - 0.34 10.8 4.0 0.26 11.2 1.1 2.2 2 0 0 2 2 2 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain Glyco_transf_49 PF13896.6 CBK25045.2 - 1.8e-09 37.4 3.6 3.4e-09 36.5 0.5 2.4 2 1 0 2 2 2 1 Glycosyl-transferase for dystroglycan FBA_1 PF07734.13 CBK25045.2 - 0.00096 19.1 0.8 0.0032 17.4 0.4 2.0 1 1 1 2 2 2 2 F-box associated OSK PF17182.4 CBK25045.2 - 0.48 9.6 4.1 0.23 10.7 1.3 2.0 2 1 0 2 2 2 0 OSK domain RNase_P_pop3 PF08228.11 CBK25046.2 - 0.12 12.4 0.0 0.23 11.5 0.0 1.4 1 0 0 1 1 1 0 RNase P subunit Pop3 Ribosomal_L7Ae PF01248.26 CBK25047.2 - 3e-21 75.0 0.6 5.1e-21 74.2 0.6 1.4 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.11 CBK25047.2 - 0.076 13.1 0.0 0.13 12.3 0.0 1.4 1 0 0 1 1 1 0 RNase P subunit Pop3 Efg1 PF10153.9 CBK25047.2 - 0.37 11.2 3.8 0.31 11.4 1.8 1.9 2 0 0 2 2 2 0 rRNA-processing protein Efg1 DUF563 PF04577.14 CBK25049.2 - 1.6e-19 70.9 1.1 3.5e-19 69.8 1.0 1.7 1 1 1 2 2 2 1 Protein of unknown function (DUF563) Na_Ca_ex PF01699.24 CBK25052.2 - 1.1e-26 93.5 7.4 1.1e-26 93.5 7.4 2.1 2 0 0 2 2 2 2 Sodium/calcium exchanger protein Zip PF02535.22 CBK25053.2 - 1.9e-10 40.5 16.1 3.1e-08 33.2 4.1 2.9 2 1 1 3 3 3 2 ZIP Zinc transporter MTBP_N PF14918.6 CBK25053.2 - 0.081 12.4 0.2 2.4 7.6 0.0 2.0 1 1 1 2 2 2 0 MDM2-binding Ribosomal_S3Ae PF01015.18 CBK25054.2 - 1.9e-84 282.3 2.9 2.5e-84 281.9 2.9 1.1 1 0 0 1 1 1 1 Ribosomal S3Ae family SUI1 PF01253.22 CBK25054.2 - 0.0012 19.3 0.4 0.0059 17.1 0.2 2.2 1 1 1 2 2 2 1 Translation initiation factor SUI1 Abhydro_lipase PF04083.16 CBK25054.2 - 0.022 14.3 0.1 0.067 12.8 0.0 1.8 2 0 0 2 2 2 0 Partial alpha/beta-hydrolase lipase region DUF3395 PF11875.8 CBK25054.2 - 0.048 13.5 0.1 0.19 11.6 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3395) Ist1 PF03398.14 CBK25055.2 - 6.3e-10 39.2 0.1 6.3e-10 39.2 0.1 2.0 2 0 0 2 2 2 1 Regulator of Vps4 activity in the MVB pathway Menin PF05053.13 CBK25055.2 - 3.6 5.8 15.0 4.4 5.5 15.0 1.1 1 0 0 1 1 1 0 Menin Nop14 PF04147.12 CBK25055.2 - 4.1 5.5 32.8 6.5 4.8 32.8 1.3 1 0 0 1 1 1 0 Nop14-like family SNF2_N PF00176.23 CBK25056.2 - 1.3e-54 185.3 0.0 1.8e-54 184.8 0.0 1.1 1 0 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.15 CBK25056.2 - 4.4e-06 26.8 0.0 6.5e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 CBK25056.2 - 4e-05 23.4 0.0 6.3e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase DEAD_2 PF06733.15 CBK25056.2 - 0.042 13.5 0.1 0.071 12.7 0.1 1.3 1 0 0 1 1 1 0 DEAD_2 Helicase_C PF00271.31 CBK25057.2 - 2.9e-11 43.7 0.0 4.2e-11 43.2 0.0 1.2 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Pkinase PF00069.25 CBK25058.2 - 3.2e-21 75.9 0.0 4.3e-21 75.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBK25058.2 - 2.6e-14 53.2 0.0 4.1e-14 52.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CBK25058.2 - 0.037 13.3 0.0 0.061 12.6 0.0 1.4 1 1 0 1 1 1 0 Kinase-like TPR_19 PF14559.6 CBK25059.2 - 1e-10 41.9 12.1 0.00035 21.0 2.1 4.8 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.6 CBK25059.2 - 2.9e-08 34.2 3.7 0.016 15.8 0.0 4.8 5 0 0 5 5 5 2 Tetratricopeptide repeat ANAPC3 PF12895.7 CBK25059.2 - 1.9e-06 28.0 5.5 0.029 14.6 0.4 3.7 4 0 0 4 4 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.6 CBK25059.2 - 8.5e-06 26.2 9.0 4.5 8.4 0.1 5.9 5 1 1 6 6 5 2 Tetratricopeptide repeat TPR_2 PF07719.17 CBK25059.2 - 3.1e-05 23.8 11.6 0.0028 17.6 0.4 5.4 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_8 PF13181.6 CBK25059.2 - 0.00055 19.9 6.8 0.016 15.4 0.2 4.7 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_17 PF13431.6 CBK25059.2 - 0.004 17.4 0.6 0.06 13.7 0.2 3.2 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_11 PF13414.6 CBK25059.2 - 0.0053 16.4 1.0 0.55 10.0 0.1 3.6 4 0 0 4 4 4 1 TPR repeat TPR_12 PF13424.6 CBK25059.2 - 0.013 15.7 0.4 0.013 15.7 0.4 4.8 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_20 PF14561.6 CBK25059.2 - 0.026 14.9 6.4 1.6 9.1 0.0 3.4 3 1 0 3 3 3 0 Tetratricopeptide repeat MNE1 PF13762.6 CBK25059.2 - 0.037 14.0 1.7 0.43 10.6 0.3 2.2 1 1 1 2 2 2 0 Mitochondrial splicing apparatus component Clathrin_H_link PF13838.6 CBK25059.2 - 0.055 13.4 0.3 0.22 11.5 0.1 2.2 1 1 1 2 2 2 0 Clathrin-H-link TPR_1 PF00515.28 CBK25059.2 - 0.069 13.0 11.7 0.13 12.1 0.3 4.3 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_10 PF13374.6 CBK25059.2 - 0.18 11.7 6.9 1.5 8.8 0.4 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat UPF0029 PF01205.19 CBK25059.2 - 0.19 12.1 0.4 3.8 7.9 0.1 2.8 2 1 0 2 2 2 0 Uncharacterized protein family UPF0029 TPR_4 PF07721.14 CBK25059.2 - 0.23 12.2 0.9 5.2 8.0 0.0 3.4 4 0 0 4 4 2 0 Tetratricopeptide repeat TPR_6 PF13174.6 CBK25059.2 - 7.7 7.4 7.2 11 6.8 0.1 4.1 5 0 0 5 5 4 0 Tetratricopeptide repeat His_Phos_1 PF00300.22 CBK25060.2 - 1.1e-34 119.9 0.0 1.5e-34 119.4 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) 6PF2K PF01591.18 CBK25060.2 - 9.4e-32 110.1 0.1 1.3e-31 109.6 0.1 1.2 1 0 0 1 1 1 1 6-phosphofructo-2-kinase Bacteroid_pep PF14406.6 CBK25061.2 - 0.066 13.6 0.3 0.066 13.6 0.3 2.6 2 0 0 2 2 2 0 Ribosomally synthesized peptide in Bacteroidetes DUF1192 PF06698.11 CBK25061.2 - 0.94 9.6 16.4 1.6 8.9 0.5 5.5 5 0 0 5 5 5 0 Protein of unknown function (DUF1192) VWA_2 PF13519.6 CBK25061.2 - 2.8 8.6 15.7 5.3 7.7 0.1 4.5 4 1 0 4 4 4 0 von Willebrand factor type A domain PNP_UDP_1 PF01048.20 CBK25062.2 - 1.2e-32 113.0 0.0 1.6e-32 112.7 0.0 1.0 1 0 0 1 1 1 1 Phosphorylase superfamily SprA-related PF12118.8 CBK25063.2 - 1.3 8.1 7.3 1.4 8.0 7.3 1.1 1 0 0 1 1 1 0 SprA-related family VIT1 PF01988.19 CBK25063.2 - 1.9 8.3 5.7 6.2 6.6 5.7 1.8 1 1 0 1 1 1 0 VIT family PHD PF00628.29 CBK25064.2 - 6.7e-07 29.1 14.6 6.7e-07 29.1 14.6 4.0 3 2 2 5 5 5 1 PHD-finger TFIID_NTD2 PF04494.15 CBK25064.2 - 0.21 11.8 1.3 0.33 11.2 0.2 1.8 2 0 0 2 2 2 0 WD40 associated region in TFIID subunit, NTD2 domain Epimerase PF01370.21 CBK25065.2 - 3.5e-41 141.3 0.0 4.4e-41 140.9 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 CBK25065.2 - 1.1e-36 127.0 0.0 1.4e-36 126.6 0.0 1.1 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 CBK25065.2 - 9e-11 41.4 0.0 3e-09 36.4 0.0 2.6 3 0 0 3 3 3 1 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.19 CBK25065.2 - 9.5e-10 37.9 0.0 4.8e-09 35.6 0.0 1.8 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 CBK25065.2 - 2e-07 30.4 0.0 3.1e-07 29.8 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.6 CBK25065.2 - 1.7e-05 24.8 0.0 2.8e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.12 CBK25065.2 - 0.0052 16.0 0.0 0.008 15.4 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein HAT_KAT11 PF08214.11 CBK25066.2 - 5.6e-26 91.6 0.0 5.4e-25 88.4 0.0 2.4 2 1 0 2 2 2 1 Histone acetylation protein Bromodomain PF00439.25 CBK25066.2 - 7.8e-21 73.9 0.0 3.3e-20 71.9 0.0 2.1 1 0 0 1 1 1 1 Bromodomain PHD PF00628.29 CBK25066.2 - 0.0065 16.3 7.2 0.0065 16.3 7.2 3.6 4 0 0 4 4 4 1 PHD-finger DUF902 PF06001.13 CBK25066.2 - 0.1 13.1 4.8 0.13 12.7 3.0 2.1 2 0 0 2 2 2 0 Domain of Unknown Function (DUF902) Utp14 PF04615.13 CBK25068.2 - 7.3e-72 243.1 65.5 4.3e-71 240.5 65.5 1.9 1 1 0 1 1 1 1 Utp14 protein Peptidase_M18 PF02127.15 CBK25069.2 - 1.5e-85 287.6 0.1 1.9e-85 287.3 0.1 1.0 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Peptidase_M42 PF05343.14 CBK25069.2 - 2.2e-05 23.6 0.0 3.7e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 M42 glutamyl aminopeptidase He_PIG PF05345.12 CBK25070.2 - 2.4e-16 59.6 31.3 2.3e-06 27.7 10.0 4.9 4 1 0 4 4 4 3 Putative Ig domain Big_9 PF17963.1 CBK25070.2 - 0.0096 16.6 3.6 0.0096 16.6 3.6 3.7 3 2 1 4 4 4 1 Bacterial Ig domain Cadherin PF00028.17 CBK25070.2 - 0.021 15.2 0.4 0.086 13.3 0.0 2.2 2 0 0 2 2 2 0 Cadherin domain Baculo_11_kDa PF06143.11 CBK25070.2 - 0.1 12.2 0.1 0.2 11.2 0.1 1.4 1 0 0 1 1 1 0 Baculovirus 11 kDa family Cadherin_5 PF17892.1 CBK25070.2 - 0.11 12.5 1.8 0.27 11.2 0.3 2.3 2 1 0 2 2 2 0 Cadherin-like domain EphA2_TM PF14575.6 CBK25070.2 - 0.11 13.3 0.1 0.37 11.7 0.0 1.9 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Saf_2TM PF18303.1 CBK25070.2 - 0.25 10.9 0.4 0.65 9.6 0.1 1.7 2 0 0 2 2 2 0 SAVED-fused 2TM effector domain COX5A PF02284.16 CBK25072.2 - 0.0014 18.6 1.4 0.0031 17.5 1.3 1.7 1 1 0 1 1 1 1 Cytochrome c oxidase subunit Va bZIP_1 PF00170.21 CBK25072.2 - 0.0061 16.6 5.3 0.47 10.6 3.8 2.5 2 0 0 2 2 2 1 bZIP transcription factor Baculo_PEP_C PF04513.12 CBK25072.2 - 0.012 15.7 1.8 0.026 14.6 1.8 1.6 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus TACC_C PF05010.14 CBK25072.2 - 0.014 15.2 12.4 0.037 13.8 12.3 2.0 1 1 0 1 1 1 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal CortBP2 PF09727.9 CBK25072.2 - 0.018 15.0 9.5 0.026 14.4 9.5 1.5 1 1 0 1 1 1 0 Cortactin-binding protein-2 FAM76 PF16046.5 CBK25072.2 - 0.018 14.4 8.0 0.022 14.1 8.0 1.1 1 0 0 1 1 1 0 FAM76 protein ALO PF04030.14 CBK25072.2 - 0.065 13.0 1.0 0.083 12.7 1.0 1.1 1 0 0 1 1 1 0 D-arabinono-1,4-lactone oxidase ZapB PF06005.12 CBK25072.2 - 0.095 13.2 10.7 9 6.8 2.4 2.7 1 1 1 2 2 2 0 Cell division protein ZapB NYD-SP28_assoc PF14775.6 CBK25072.2 - 0.1 12.7 2.8 0.17 12.0 0.4 2.4 2 1 0 2 2 2 0 Sperm tail C-terminal domain DUF4407 PF14362.6 CBK25072.2 - 0.15 11.3 6.9 0.23 10.8 6.9 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) bZIP_2 PF07716.15 CBK25072.2 - 0.16 12.0 6.7 1.6 8.9 4.1 2.6 2 0 0 2 2 2 0 Basic region leucine zipper Jnk-SapK_ap_N PF09744.9 CBK25072.2 - 0.17 12.1 11.6 0.087 13.1 9.5 1.6 1 1 0 1 1 1 0 JNK_SAPK-associated protein-1 Golgin_A5 PF09787.9 CBK25072.2 - 0.2 11.1 12.4 0.26 10.7 12.4 1.1 1 0 0 1 1 1 0 Golgin subfamily A member 5 JHD PF17811.1 CBK25072.2 - 0.23 12.0 4.4 5.5 7.6 0.1 2.4 2 1 0 2 2 2 0 Jumonji helical domain DUF641 PF04859.12 CBK25072.2 - 0.29 11.5 7.8 1.3 9.4 0.8 2.3 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) Occludin_ELL PF07303.13 CBK25072.2 - 0.37 11.5 6.2 0.3 11.8 0.3 2.8 2 1 1 3 3 3 0 Occludin homology domain APG6_N PF17675.1 CBK25072.2 - 0.46 11.0 11.9 1.1 9.8 11.9 1.8 1 1 0 1 1 1 0 Apg6 coiled-coil region DivIC PF04977.15 CBK25072.2 - 1.2 9.0 8.8 0.87 9.4 2.0 2.8 1 1 2 3 3 3 0 Septum formation initiator LMBR1 PF04791.16 CBK25072.2 - 9.4 5.0 6.3 9.5 5.0 6.3 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein LSM14 PF12701.7 CBK25074.2 - 5.7e-18 64.8 1.2 9.8e-18 64.0 1.2 1.4 1 0 0 1 1 1 1 Scd6-like Sm domain Spore_coat_CotO PF14153.6 CBK25074.2 - 0.13 12.2 0.1 0.13 12.2 0.1 1.7 2 0 0 2 2 2 0 Spore coat protein CotO FDF PF09532.10 CBK25074.2 - 9.3 7.2 11.0 16 6.5 3.5 2.7 1 1 1 2 2 2 0 FDF domain ABC_membrane PF00664.23 CBK25075.2 - 7.7e-69 232.4 39.2 7.6e-35 120.9 15.7 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 CBK25075.2 - 2.6e-53 180.2 0.7 4.2e-30 105.1 0.0 2.8 3 0 0 3 3 2 2 ABC transporter SMC_N PF02463.19 CBK25075.2 - 2.3e-09 37.0 12.1 0.0045 16.5 0.2 4.4 4 1 1 5 5 5 3 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 CBK25075.2 - 3.7e-07 30.2 0.2 0.011 15.8 0.0 3.1 2 0 0 2 2 2 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 CBK25075.2 - 8.9e-07 29.0 0.1 0.0029 17.5 0.0 2.6 2 0 0 2 2 2 2 RsgA GTPase Dynamin_N PF00350.23 CBK25075.2 - 2.5e-05 24.4 3.5 0.012 15.7 0.0 3.5 3 0 0 3 3 3 1 Dynamin family AAA_16 PF13191.6 CBK25075.2 - 0.00028 21.3 0.4 1.1 9.7 0.0 3.1 3 0 0 3 3 3 2 AAA ATPase domain AAA_29 PF13555.6 CBK25075.2 - 0.00034 20.3 0.3 0.34 10.7 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.6 CBK25075.2 - 0.00062 20.3 12.4 0.011 16.2 0.1 3.6 3 0 0 3 3 3 1 AAA domain Sec62 PF03839.16 CBK25075.2 - 0.00096 18.7 0.7 0.0024 17.4 0.7 1.6 1 0 0 1 1 1 1 Translocation protein Sec62 AAA_24 PF13479.6 CBK25075.2 - 0.002 17.9 0.0 0.011 15.5 0.0 2.2 2 1 0 2 2 2 1 AAA domain AAA_21 PF13304.6 CBK25075.2 - 0.0026 17.6 0.5 6.6 6.4 0.0 3.5 2 1 1 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system DUF815 PF05673.13 CBK25075.2 - 0.0064 15.7 0.1 1.7 7.7 0.1 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_22 PF13401.6 CBK25075.2 - 0.01 16.1 0.0 2.4 8.4 0.0 2.9 2 1 0 2 2 2 0 AAA domain DUF87 PF01935.17 CBK25075.2 - 0.033 14.3 3.8 0.5 10.4 0.1 3.1 3 0 0 3 3 3 0 Helicase HerA, central domain Roc PF08477.13 CBK25075.2 - 0.06 13.6 0.5 11 6.2 0.1 3.5 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase AIG1 PF04548.16 CBK25075.2 - 0.066 12.5 0.4 2.5 7.4 0.0 2.6 2 0 0 2 2 2 0 AIG1 family AAA PF00004.29 CBK25075.2 - 0.066 13.6 0.3 19 5.7 0.0 3.3 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) BNIP3 PF06553.12 CBK25075.2 - 0.08 12.6 0.1 0.14 11.8 0.1 1.3 1 0 0 1 1 1 0 BNIP3 Zeta_toxin PF06414.12 CBK25075.2 - 0.084 12.1 0.0 4.2 6.6 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin AAA_7 PF12775.7 CBK25075.2 - 0.12 11.9 0.0 13 5.3 0.0 2.5 2 0 0 2 2 2 0 P-loop containing dynein motor region GTP_EFTU PF00009.27 CBK25075.2 - 0.25 10.8 1.0 2.7 7.5 0.0 2.8 3 0 0 3 3 3 0 Elongation factor Tu GTP binding domain AAA_15 PF13175.6 CBK25075.2 - 0.57 9.8 6.8 0.37 10.4 0.1 3.0 3 0 0 3 3 3 0 AAA ATPase domain Astro_capsid_p PF12226.8 CBK25075.2 - 6.4 5.8 7.2 9.9 5.2 7.2 1.2 1 0 0 1 1 1 0 Turkey astrovirus capsid protein GTP_EFTU PF00009.27 CBK25076.2 - 0.073 12.6 0.0 0.079 12.5 0.0 1.2 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain dCMP_cyt_deam_1 PF00383.23 CBK25076.2 - 0.14 12.1 0.0 0.21 11.5 0.0 1.2 1 0 0 1 1 1 0 Cytidine and deoxycytidylate deaminase zinc-binding region TMEM154 PF15102.6 CBK25077.2 - 0.07 13.0 1.5 0.14 12.1 1.5 1.4 1 0 0 1 1 1 0 TMEM154 protein family DUF202 PF02656.15 CBK25077.2 - 0.082 13.4 8.7 0.36 11.3 0.0 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF202) Saf_2TM PF18303.1 CBK25077.2 - 0.47 10.0 10.3 0.53 9.9 0.4 2.2 1 1 1 2 2 2 0 SAVED-fused 2TM effector domain TMEM132D_C PF15706.5 CBK25077.2 - 9.1 6.1 9.7 0.57 10.0 4.2 1.8 2 1 0 2 2 2 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term PA28_beta PF02252.18 CBK25078.2 - 1.4e-35 122.1 0.0 1.7e-35 121.8 0.0 1.0 1 0 0 1 1 1 1 Proteasome activator pa28 beta subunit Pesticin PF16754.5 CBK25078.2 - 0.0086 16.0 0.0 0.0099 15.8 0.0 1.1 1 0 0 1 1 1 1 Bacterial toxin homologue of phage lysozyme, C-term HSP70 PF00012.20 CBK25079.2 - 3.7e-63 213.7 0.1 2.5e-62 210.9 0.1 1.8 1 1 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 CBK25079.2 - 2.6e-11 42.9 0.0 5.3e-05 22.2 0.0 3.3 3 1 0 3 3 3 3 MreB/Mbl protein StbA PF06406.11 CBK25079.2 - 0.0021 17.4 0.0 0.069 12.4 0.0 2.3 2 0 0 2 2 2 1 StbA protein DDR PF08841.10 CBK25079.2 - 0.005 15.9 0.0 0.71 8.8 0.0 2.6 3 0 0 3 3 3 2 Diol dehydratase reactivase ATPase-like domain HSP70 PF00012.20 CBK25080.2 - 7.3e-62 209.4 0.0 1e-61 208.9 0.0 1.1 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 CBK25080.2 - 7e-09 34.9 0.0 3.1e-08 32.8 0.0 2.0 1 1 0 1 1 1 1 MreB/Mbl protein StbA PF06406.11 CBK25080.2 - 0.0088 15.3 0.0 3.5 6.8 0.0 2.2 1 1 0 2 2 2 2 StbA protein DDR PF08841.10 CBK25080.2 - 0.029 13.4 0.0 0.15 11.0 0.0 2.1 3 1 0 4 4 4 0 Diol dehydratase reactivase ATPase-like domain CBM_25 PF03423.13 CBK25080.2 - 0.043 14.1 0.2 0.093 13.0 0.2 1.5 1 0 0 1 1 1 0 Carbohydrate binding domain (family 25) NEMP PF10225.9 CBK25081.2 - 3.9e-18 66.0 9.1 4.8e-18 65.7 9.1 1.0 1 0 0 1 1 1 1 NEMP family Coa1 PF08695.10 CBK25082.2 - 7e-09 35.5 0.0 9.4e-09 35.0 0.0 1.2 1 0 0 1 1 1 1 Cytochrome oxidase complex assembly protein 1 He_PIG PF05345.12 CBK25083.2 - 2.2e-16 59.8 16.8 2e-05 24.7 2.5 5.9 5 0 0 5 5 5 3 Putative Ig domain ASFV_J13L PF05568.11 CBK25083.2 - 0.013 15.3 1.0 0.033 14.0 1.0 1.6 1 0 0 1 1 1 0 African swine fever virus J13L protein COX2_TM PF02790.15 CBK25083.2 - 0.021 14.9 0.5 0.062 13.4 0.5 1.7 1 0 0 1 1 1 0 Cytochrome C oxidase subunit II, transmembrane domain Soyouz_module PF14313.6 CBK25083.2 - 0.077 12.8 0.2 0.19 11.5 0.2 1.6 1 0 0 1 1 1 0 N-terminal region of Paramyxovirinae phosphoprotein (P) FeoB_associated PF12669.7 CBK25083.2 - 2.8 8.4 7.6 7.3 7.1 7.6 1.7 1 0 0 1 1 1 0 FeoB-associated Cys-rich membrane protein DUF2828 PF11443.8 CBK25084.2 - 0.021 13.0 0.0 0.031 12.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) GP17 PF17420.2 CBK25084.2 - 0.13 12.4 0.3 0.3 11.2 0.3 1.6 1 0 0 1 1 1 0 Superinfection exclusion gene product 17 LRR_4 PF12799.7 CBK25084.2 - 2.8 8.5 5.4 17 6.0 5.5 2.1 1 1 0 1 1 1 0 Leucine Rich repeats (2 copies) Aldo_ket_red PF00248.21 CBK25085.2 - 7.8e-54 182.9 0.0 1.6e-53 181.8 0.0 1.5 1 1 0 1 1 1 1 Aldo/keto reductase family Pkinase PF00069.25 CBK25086.2 - 1.9e-65 220.8 0.1 3.7e-65 219.9 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBK25086.2 - 1.2e-37 129.6 0.0 2e-37 128.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CBK25086.2 - 9.9e-06 25.1 0.0 1.9e-05 24.2 0.0 1.6 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 CBK25086.2 - 2.7e-05 23.6 0.2 6.4e-05 22.4 0.2 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 CBK25086.2 - 0.00031 20.4 0.3 0.0006 19.4 0.3 1.4 1 0 0 1 1 1 1 RIO1 family Seadorna_VP7 PF07387.11 CBK25086.2 - 0.00062 18.9 0.0 0.0013 17.8 0.0 1.5 1 0 0 1 1 1 1 Seadornavirus VP7 Pkinase_fungal PF17667.1 CBK25086.2 - 0.0011 17.8 0.0 0.0018 17.1 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 CBK25086.2 - 0.0043 17.0 0.0 0.0085 16.0 0.0 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family Nse4_C PF08743.10 CBK25087.2 - 2.8e-10 40.3 0.2 9.2e-10 38.7 0.0 1.8 2 1 0 2 2 2 1 Nse4 C-terminal RR_TM4-6 PF06459.12 CBK25087.2 - 0.067 13.0 2.2 0.088 12.6 2.2 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Pkinase PF00069.25 CBK25088.2 - 4.3e-09 36.1 0.4 6.4e-09 35.6 0.0 1.4 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBK25088.2 - 0.0071 15.7 2.0 0.026 13.8 0.1 2.4 2 1 0 2 2 2 1 Protein tyrosine kinase DDE_Tnp_ISL3 PF01610.17 CBK25088.2 - 0.0085 15.8 0.5 0.021 14.6 0.5 1.7 1 1 0 1 1 1 1 Transposase FlgN PF05130.12 CBK25088.2 - 0.02 15.4 3.4 0.02 15.4 3.4 1.6 2 0 0 2 2 2 0 FlgN protein PFK PF00365.20 CBK25089.2 - 4.3e-40 137.8 0.0 4.9e-38 131.1 0.0 2.2 2 0 0 2 2 2 2 Phosphofructokinase Helicase_C_3 PF13625.6 CBK25089.2 - 0.16 12.1 0.0 0.32 11.1 0.0 1.4 1 0 0 1 1 1 0 Helicase conserved C-terminal domain Na_H_antiporter PF03553.14 CBK25090.2 - 1e-41 143.1 17.8 1e-41 143.1 17.8 2.2 2 0 0 2 2 2 1 Na+/H+ antiporter family FixP_N PF14715.6 CBK25090.2 - 0.024 14.4 0.2 0.024 14.4 0.2 3.6 6 0 0 6 6 6 0 N-terminal domain of cytochrome oxidase-cbb3, FixP DUF1840 PF08895.11 CBK25090.2 - 0.22 11.8 1.9 0.39 11.1 1.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1840) DUF3278 PF11683.8 CBK25090.2 - 2.6 8.1 8.6 3.9 7.6 1.8 3.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3278) Rab5ip PF07019.12 CBK25090.2 - 5.6 7.6 13.7 17 6.1 0.9 4.5 3 1 0 3 3 3 0 Rab5-interacting protein (Rab5ip) G-patch PF01585.23 CBK25091.2 - 6.5e-12 45.1 2.6 6.5e-12 45.1 2.6 1.7 2 0 0 2 2 2 1 G-patch domain G-patch_2 PF12656.7 CBK25091.2 - 7.3e-05 22.8 0.8 0.00014 21.9 0.8 1.5 1 0 0 1 1 1 1 G-patch domain DEAD PF00270.29 CBK25092.2 - 4.2e-20 72.2 0.0 1.1e-19 70.9 0.0 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CBK25092.2 - 2.3e-12 47.2 0.1 1.8e-11 44.3 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain CMS1 PF14617.6 CBK25092.2 - 0.004 16.5 0.5 0.014 14.8 0.0 2.1 2 0 0 2 2 2 1 U3-containing 90S pre-ribosomal complex subunit UTP25 PF06862.12 CBK25092.2 - 0.076 11.8 0.0 0.12 11.1 0.0 1.3 1 0 0 1 1 1 0 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 Bac_export_2 PF01312.19 CBK25092.2 - 1.1 8.3 2.8 1.8 7.7 2.8 1.3 1 0 0 1 1 1 0 FlhB HrpN YscU SpaS Family Exo_endo_phos PF03372.23 CBK25093.2 - 0.0025 17.4 0.0 0.0037 16.8 0.0 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family TMEM144 PF07857.12 CBK25094.2 - 1.1e-84 284.3 20.8 1.3e-84 284.0 20.8 1.1 1 0 0 1 1 1 1 Transmembrane family, TMEM144 of transporters Sugar_transport PF06800.12 CBK25094.2 - 2.3e-10 40.3 16.7 3.9e-08 33.0 1.6 2.2 2 0 0 2 2 2 2 Sugar transport protein Ureide_permease PF07168.11 CBK25094.2 - 0.0095 14.7 1.4 0.0095 14.7 1.4 2.8 2 1 0 2 2 2 1 Ureide permease Ribosomal_S8e PF01201.22 CBK25095.2 - 3.3e-38 130.9 0.0 4.2e-38 130.6 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S8e zf-RING_5 PF14634.6 CBK25096.2 - 1.9e-08 34.2 10.0 3e-08 33.5 10.0 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 CBK25096.2 - 0.00021 21.5 11.3 0.00034 20.9 11.3 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 CBK25096.2 - 0.00036 20.3 10.2 0.00055 19.8 10.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 CBK25096.2 - 0.0035 17.1 11.8 0.0059 16.4 11.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CBK25096.2 - 0.022 14.6 11.2 0.043 13.7 11.2 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 CBK25096.2 - 0.042 13.7 11.6 0.082 12.8 11.6 1.5 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 DZR PF12773.7 CBK25096.2 - 0.066 13.3 6.6 0.12 12.4 6.6 1.4 1 0 0 1 1 1 0 Double zinc ribbon zf-RING_10 PF16685.5 CBK25096.2 - 0.077 13.2 5.1 0.17 12.1 5.1 1.6 1 0 0 1 1 1 0 zinc RING finger of MSL2 Zn_ribbon_17 PF17120.5 CBK25096.2 - 0.82 9.3 6.4 1.3 8.7 6.4 1.2 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type Zn_Tnp_IS1595 PF12760.7 CBK25096.2 - 3.5 7.7 7.4 6.9 6.7 1.3 2.5 1 1 1 2 2 2 0 Transposase zinc-ribbon domain zf-RING_4 PF14570.6 CBK25096.2 - 9.5 6.1 9.4 17 5.3 9.4 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain LMBR1 PF04791.16 CBK25097.2 - 7.9e-26 91.0 9.7 1e-25 90.7 9.7 1.1 1 0 0 1 1 1 1 LMBR1-like membrane protein ATP-grasp_5 PF13549.6 CBK25099.2 - 3.8e-78 262.0 0.6 6.4e-78 261.2 0.0 1.7 2 0 0 2 2 2 1 ATP-grasp domain Succ_CoA_lig PF13607.6 CBK25099.2 - 3.7e-57 192.0 0.5 1.1e-56 190.5 0.5 1.9 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.6 CBK25099.2 - 3.6e-23 82.3 2.0 5.1e-22 78.5 0.1 3.3 3 0 0 3 3 3 1 CoA binding domain CoA_binding PF02629.19 CBK25099.2 - 1.6e-13 51.2 0.8 4.9e-13 49.6 0.1 2.4 2 0 0 2 2 1 1 CoA binding domain Acetyltransf_1 PF00583.25 CBK25099.2 - 2.4e-09 37.4 0.1 4.8e-09 36.5 0.1 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_3 PF13302.7 CBK25099.2 - 9.8e-06 26.3 0.0 2.4e-05 25.0 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain ATP-grasp_2 PF08442.10 CBK25099.2 - 7.5e-05 22.4 0.1 0.00021 20.9 0.1 1.8 1 0 0 1 1 1 1 ATP-grasp domain Acetyltransf_4 PF13420.7 CBK25099.2 - 0.00013 22.2 0.0 0.00029 21.0 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 CBK25099.2 - 0.00031 20.8 0.9 0.0044 17.1 0.1 2.9 3 0 0 3 3 3 1 GCN5-related N-acetyl-transferase Acetyltransf_10 PF13673.7 CBK25099.2 - 0.0041 17.1 0.1 0.0086 16.0 0.1 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain CPSase_L_D2 PF02786.17 CBK25099.2 - 0.0084 15.6 0.2 0.034 13.7 0.1 2.0 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Acetyltransf_7 PF13508.7 CBK25099.2 - 0.011 16.1 0.0 0.027 14.9 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain RNA_pol_Rpb1_7 PF04990.12 CBK25100.2 - 0.069 13.2 0.0 0.092 12.7 0.0 1.2 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 7 DENN PF02141.21 CBK25101.2 - 5.3e-33 114.5 2.0 1.2e-32 113.4 2.0 1.5 1 0 0 1 1 1 1 DENN (AEX-3) domain dDENN PF03455.19 CBK25101.2 - 3.4e-08 33.4 0.1 6.6e-08 32.4 0.1 1.5 1 0 0 1 1 1 1 dDENN domain PDZ PF00595.24 CBK25101.2 - 0.011 16.1 0.1 0.032 14.6 0.1 1.8 1 1 0 1 1 1 0 PDZ domain PDZ_6 PF17820.1 CBK25101.2 - 0.04 13.8 0.0 0.11 12.4 0.0 1.8 1 0 0 1 1 1 0 PDZ domain SPA PF08616.10 CBK25101.2 - 0.074 13.0 0.0 0.19 11.7 0.0 1.6 1 0 0 1 1 1 0 Stabilization of polarity axis CN_hydrolase PF00795.22 CBK25102.2 - 1.3e-52 178.7 0.0 1.5e-52 178.5 0.0 1.0 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase PHA_synth_III_E PF09712.10 CBK25102.2 - 0.15 11.1 0.1 0.3 10.1 0.1 1.4 1 0 0 1 1 1 0 Poly(R)-hydroxyalkanoic acid synthase subunit (PHA_synth_III_E) MIF4G PF02854.19 CBK25103.2 - 0.015 15.0 0.1 0.036 13.7 0.1 1.5 1 1 0 1 1 1 0 MIF4G domain Pico_P1A PF02226.16 CBK25103.2 - 0.029 14.4 0.3 0.14 12.2 0.7 1.9 2 0 0 2 2 2 0 Picornavirus coat protein (VP4) PIN_12 PF16289.5 CBK25103.2 - 8.3 6.9 8.7 25 5.3 1.2 2.8 2 1 0 2 2 2 0 PIN domain MIF4G PF02854.19 CBK25104.2 - 3e-05 23.7 0.9 6.3e-05 22.7 0.9 1.5 1 0 0 1 1 1 1 MIF4G domain Caudo_TAP PF02413.17 CBK25104.2 - 0.014 15.6 1.5 0.024 14.8 1.2 1.6 1 1 0 1 1 1 0 Caudovirales tail fibre assembly protein, lambda gpK Ribosomal_L18A PF01775.17 CBK25105.2 - 8.5e-51 171.1 0.2 1.2e-50 170.6 0.2 1.2 1 0 0 1 1 1 1 Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A Ribosomal_L32e PF01655.18 CBK25106.2 - 3.2e-47 159.4 0.1 4e-47 159.1 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L32 CutC PF03932.14 CBK25107.2 - 6.9e-77 257.5 2.7 8.3e-77 257.2 2.7 1.1 1 0 0 1 1 1 1 CutC family DeoC PF01791.9 CBK25107.2 - 0.025 14.2 0.1 0.58 9.7 0.1 2.1 1 1 1 2 2 2 0 DeoC/LacD family aldolase QRPTase_C PF01729.19 CBK25107.2 - 0.04 13.7 0.1 0.11 12.2 0.0 1.7 1 1 1 2 2 2 0 Quinolinate phosphoribosyl transferase, C-terminal domain Pantoate_transf PF02548.15 CBK25107.2 - 0.041 13.3 0.5 0.17 11.3 0.1 1.8 1 1 1 2 2 2 0 Ketopantoate hydroxymethyltransferase TMP-TENI PF02581.17 CBK25107.2 - 0.06 12.7 0.1 0.14 11.5 0.1 1.6 1 0 0 1 1 1 0 Thiamine monophosphate synthase Complex1_51K PF01512.17 CBK25108.2 - 6.9e-43 146.1 0.0 1.1e-42 145.5 0.0 1.2 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase 51 Kd subunit NADH_4Fe-4S PF10589.9 CBK25108.2 - 7.4e-25 86.9 0.1 1.8e-24 85.6 0.1 1.6 2 0 0 2 2 2 1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region SLBB PF10531.9 CBK25108.2 - 3.4e-07 30.0 0.1 8.6e-07 28.7 0.0 1.8 2 0 0 2 2 2 1 SLBB domain MMR_HSR1 PF01926.23 CBK25110.2 - 6.4e-19 68.1 0.3 1.2e-15 57.6 0.0 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.18 CBK25110.2 - 9.2e-08 31.8 0.5 1.2e-05 24.9 0.0 2.3 2 0 0 2 2 2 2 Ferrous iron transport protein B RsgA_GTPase PF03193.16 CBK25110.2 - 1.5e-06 28.2 1.5 0.0095 15.9 0.1 2.5 1 1 1 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 CBK25110.2 - 3.2e-05 23.6 3.8 0.0037 16.8 0.0 3.6 3 1 0 3 3 3 1 Elongation factor Tu GTP binding domain Arf PF00025.21 CBK25110.2 - 0.00017 21.1 0.3 0.58 9.6 0.0 2.5 2 0 0 2 2 2 2 ADP-ribosylation factor family Dynamin_N PF00350.23 CBK25110.2 - 0.0009 19.3 10.1 0.011 15.8 0.2 3.5 2 2 1 3 3 3 1 Dynamin family Roc PF08477.13 CBK25110.2 - 0.0012 19.1 0.9 0.9 9.8 0.0 2.5 2 1 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase AAA_18 PF13238.6 CBK25110.2 - 0.07 13.7 1.4 0.43 11.1 0.1 2.5 2 1 0 2 2 2 0 AAA domain PBECR2 PF18810.1 CBK25110.2 - 0.072 13.4 0.1 0.16 12.3 0.1 1.6 1 0 0 1 1 1 0 phage-Barnase-EndoU-ColicinE5/D-RelE like nuclease2 Ras PF00071.22 CBK25110.2 - 0.096 12.3 1.6 2 8.0 0.0 2.8 2 1 1 3 3 3 0 Ras family AAA_16 PF13191.6 CBK25110.2 - 0.12 12.8 0.3 0.84 10.0 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain Ku_C PF03730.14 CBK25110.2 - 0.64 10.8 3.5 1.5 9.5 3.5 1.7 1 1 0 1 1 1 0 Ku70/Ku80 C-terminal arm Clathrin_lg_ch PF01086.17 CBK25111.2 - 9.5e-16 58.5 15.6 1.3e-15 58.1 15.6 1.4 1 1 0 1 1 1 1 Clathrin light chain WD40 PF00400.32 CBK25112.2 - 5.6e-47 156.8 18.2 1.2e-10 41.8 0.1 7.2 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBK25112.2 - 4.1e-10 39.8 4.5 0.0063 16.8 0.0 5.5 2 2 4 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 CBK25112.2 - 1.3e-06 27.4 6.9 0.015 14.0 0.1 5.0 3 1 1 5 5 5 3 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 CBK25112.2 - 8.3e-06 25.0 0.3 0.04 12.9 0.0 3.6 2 1 2 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein PQQ_2 PF13360.6 CBK25112.2 - 0.0064 16.1 1.7 0.083 12.5 0.0 2.3 2 1 0 2 2 2 1 PQQ-like domain DUF1513 PF07433.11 CBK25112.2 - 0.0094 15.1 0.3 0.97 8.4 0.1 3.0 1 1 3 4 4 4 1 Protein of unknown function (DUF1513) Cytochrom_D1 PF02239.16 CBK25112.2 - 0.02 13.5 0.0 0.94 7.9 0.0 2.9 2 2 1 3 3 3 0 Cytochrome D1 heme domain PQQ_3 PF13570.6 CBK25112.2 - 0.075 13.5 0.7 18 6.0 0.1 3.8 3 1 0 3 3 3 0 PQQ-like domain Amelogenin PF02948.15 CBK25113.2 - 0.00079 20.1 51.3 0.57 10.8 22.1 2.9 1 1 2 3 3 3 3 Amelogenin DUF4573 PF15140.6 CBK25113.2 - 0.0012 18.7 25.0 0.0026 17.6 25.0 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF4573) SecE PF00584.20 CBK25114.2 - 0.0083 16.0 0.2 0.014 15.3 0.2 1.4 1 0 0 1 1 1 1 SecE/Sec61-gamma subunits of protein translocation complex BSP_II PF05432.11 CBK25114.2 - 0.17 11.5 52.9 0.24 11.1 52.9 1.2 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) GREB1 PF15782.5 CBK25114.2 - 0.55 7.3 18.7 0.58 7.2 18.7 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer MotA_ExbB PF01618.16 CBK25114.2 - 2 8.2 0.0 2 8.2 0.0 2.5 2 1 0 2 2 2 0 MotA/TolQ/ExbB proton channel family Ndc1_Nup PF09531.10 CBK25114.2 - 5.5 5.6 6.6 6.2 5.4 6.6 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup POR_N PF01855.19 CBK25115.2 - 2.2e-72 243.5 0.4 6.3e-72 242.0 0.1 1.9 2 0 0 2 2 2 1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg FAD_binding_1 PF00667.20 CBK25115.2 - 1.8e-41 142.2 0.0 3.2e-41 141.4 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 CBK25115.2 - 2.9e-25 89.2 0.1 7e-25 87.9 0.1 1.7 1 0 0 1 1 1 1 Flavodoxin POR PF01558.18 CBK25115.2 - 2.2e-22 80.0 0.0 5.9e-22 78.6 0.0 1.8 1 0 0 1 1 1 1 Pyruvate ferredoxin/flavodoxin oxidoreductase EKR PF10371.9 CBK25115.2 - 8.6e-19 67.1 0.6 2.2e-18 65.8 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function PFOR_II PF17147.4 CBK25115.2 - 7.2e-12 45.5 0.0 2.5e-11 43.8 0.0 2.0 1 0 0 1 1 1 1 Pyruvate:ferredoxin oxidoreductase core domain II Fer4_7 PF12838.7 CBK25115.2 - 5.1e-08 33.4 8.1 2.5e-07 31.2 8.3 2.3 1 1 0 1 1 1 1 4Fe-4S dicluster domain TPP_enzyme_C PF02775.21 CBK25115.2 - 2.5e-07 30.6 0.1 5.8e-07 29.4 0.1 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Fer4_16 PF13484.6 CBK25115.2 - 2.8e-07 31.3 10.5 2e-05 25.4 11.7 2.7 1 1 1 2 2 2 2 4Fe-4S double cluster binding domain NAD_binding_1 PF00175.21 CBK25115.2 - 3.1e-07 31.0 0.0 1.1e-06 29.3 0.0 2.0 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Fer4_9 PF13187.6 CBK25115.2 - 5.4e-07 29.7 11.4 0.0026 17.9 1.6 2.8 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4 PF00037.27 CBK25115.2 - 2.4e-06 27.1 23.7 0.00023 20.8 5.5 3.5 3 0 0 3 3 3 2 4Fe-4S binding domain Fer4_10 PF13237.6 CBK25115.2 - 1.4e-05 25.1 8.9 1.4e-05 25.1 8.9 2.3 3 0 0 3 3 1 1 4Fe-4S dicluster domain Fer4_21 PF14697.6 CBK25115.2 - 0.00024 21.2 14.8 0.0024 18.0 14.8 2.6 1 1 0 1 1 1 1 4Fe-4S dicluster domain Transketolase_C PF02780.20 CBK25115.2 - 0.00041 20.2 0.6 0.0018 18.1 0.1 2.3 2 0 0 2 2 2 1 Transketolase, C-terminal domain Fer4_6 PF12837.7 CBK25115.2 - 0.00052 20.0 6.7 0.00052 20.0 6.7 3.6 3 0 0 3 3 3 2 4Fe-4S binding domain Fer4_17 PF13534.6 CBK25115.2 - 0.00083 19.9 11.5 0.019 15.5 2.0 3.5 3 0 0 3 3 2 2 4Fe-4S dicluster domain Fer4_2 PF12797.7 CBK25115.2 - 0.0075 16.3 18.5 0.017 15.2 2.7 3.5 3 0 0 3 3 3 2 4Fe-4S binding domain Fer4_18 PF13746.6 CBK25115.2 - 0.035 14.3 5.7 1.5 9.1 0.8 3.1 3 0 0 3 3 2 0 4Fe-4S dicluster domain Fer4_8 PF13183.6 CBK25115.2 - 0.04 14.4 13.3 0.23 11.9 13.1 2.5 1 1 2 3 3 3 0 4Fe-4S dicluster domain Fer4_15 PF13459.6 CBK25115.2 - 0.78 10.5 7.6 10 6.9 0.3 3.0 2 0 0 2 2 2 0 4Fe-4S single cluster domain Fer4_22 PF17179.4 CBK25115.2 - 4.3 8.3 9.0 5 8.0 2.2 3.0 2 0 0 2 2 2 0 4Fe-4S dicluster domain PseudoU_synth_1 PF01416.20 CBK25116.2 - 9e-11 42.2 0.0 1.8e-10 41.2 0.0 1.5 1 0 0 1 1 1 1 tRNA pseudouridine synthase DUF2344 PF10105.9 CBK25116.2 - 0.062 13.1 0.0 0.086 12.7 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2344) DUF1883 PF08980.10 CBK25116.2 - 0.11 12.5 0.0 1.3 9.0 0.0 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF1883) GTP_EFTU PF00009.27 CBK25117.2 - 2.4e-54 183.8 0.0 3.6e-54 183.3 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 CBK25117.2 - 3.2e-40 136.9 0.0 7.9e-40 135.7 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 CBK25117.2 - 9.5e-08 32.3 0.0 2.7e-07 30.9 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 CBK25117.2 - 0.00011 22.3 0.1 0.0022 18.1 0.1 2.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase Glyco_hydro_35 PF01301.19 CBK25118.2 - 5.8e-108 361.3 1.5 7.1e-108 361.0 1.5 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 Glyco_hydro_42 PF02449.15 CBK25118.2 - 4.2e-14 52.7 0.1 1.7e-12 47.4 0.1 2.3 1 1 0 1 1 1 1 Beta-galactosidase Cellulase PF00150.18 CBK25118.2 - 0.077 12.4 0.1 0.22 10.9 0.0 1.7 2 0 0 2 2 2 0 Cellulase (glycosyl hydrolase family 5) WD40 PF00400.32 CBK25119.2 - 2.2e-21 75.7 11.4 1e-05 26.2 0.3 6.5 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBK25119.2 - 2.4e-18 66.2 1.2 3e-05 24.3 0.0 4.5 2 1 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 CBK25119.2 - 5.6e-05 23.1 0.0 0.34 10.8 0.0 3.1 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 CBK25119.2 - 0.0016 17.4 0.5 0.049 12.6 0.4 3.3 1 1 1 2 2 2 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Torus PF16131.5 CBK25120.2 - 5.5e-35 120.4 1.8 1.3e-34 119.2 1.8 1.6 1 0 0 1 1 1 1 Torus domain WW PF00397.26 CBK25120.2 - 2e-08 34.1 0.4 4.2e-08 33.1 0.4 1.5 1 0 0 1 1 1 1 WW domain zf-RanBP PF00641.18 CBK25120.2 - 1.2e-05 24.5 3.6 2.9e-05 23.3 3.6 1.8 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others RRM_1 PF00076.22 CBK25120.2 - 0.00043 20.0 0.1 0.0012 18.6 0.1 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF1952 PF09189.10 CBK25120.2 - 0.029 14.2 0.0 4.2 7.3 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1952) Nup35_RRM_2 PF14605.6 CBK25120.2 - 0.064 13.3 0.1 0.14 12.1 0.1 1.5 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Kinesin PF00225.23 CBK25121.2 - 7.5e-68 228.9 0.4 9.4e-68 228.6 0.4 1.0 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 CBK25121.2 - 5.2e-17 62.2 0.3 1e-16 61.2 0.0 1.6 2 0 0 2 2 2 1 Microtubule binding ERM PF00769.19 CBK25122.2 - 0.00048 20.0 13.0 0.00065 19.6 13.0 1.1 1 0 0 1 1 1 1 Ezrin/radixin/moesin family TMF_DNA_bd PF12329.8 CBK25122.2 - 0.00049 20.0 4.8 0.00083 19.3 4.8 1.3 1 0 0 1 1 1 1 TATA element modulatory factor 1 DNA binding YabA PF06156.13 CBK25122.2 - 0.00052 20.6 2.0 0.00087 19.9 2.0 1.3 1 0 0 1 1 1 1 Initiation control protein YabA UPF0242 PF06785.11 CBK25122.2 - 0.0014 18.8 5.8 0.0018 18.4 5.8 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0242) N-terminus Effector_1 PF04518.12 CBK25122.2 - 0.0026 17.0 0.3 0.0026 17.0 0.3 1.8 1 1 1 2 2 2 1 Effector from type III secretion system KASH_CCD PF14662.6 CBK25122.2 - 0.0072 16.2 5.9 0.011 15.5 5.9 1.2 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 or KASH ADIP PF11559.8 CBK25122.2 - 0.0073 16.4 9.6 0.011 15.9 9.6 1.2 1 0 0 1 1 1 1 Afadin- and alpha -actinin-Binding Borrelia_REV PF03978.13 CBK25122.2 - 0.0098 15.9 0.4 0.014 15.3 0.4 1.2 1 0 0 1 1 1 1 Borrelia burgdorferi REV protein FlaC_arch PF05377.11 CBK25122.2 - 0.015 15.7 1.0 0.61 10.5 0.1 2.5 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) Macoilin PF09726.9 CBK25122.2 - 0.029 13.0 5.9 0.038 12.6 5.9 1.0 1 0 0 1 1 1 0 Macoilin family Golgin_A5 PF09787.9 CBK25122.2 - 0.038 13.5 5.8 0.052 13.0 5.8 1.1 1 0 0 1 1 1 0 Golgin subfamily A member 5 CENP-H PF05837.12 CBK25122.2 - 0.039 14.4 8.1 0.059 13.8 8.1 1.3 1 0 0 1 1 1 0 Centromere protein H (CENP-H) SF-assemblin PF06705.11 CBK25122.2 - 0.052 12.9 3.9 0.084 12.2 3.9 1.2 1 0 0 1 1 1 0 SF-assemblin/beta giardin 7TMR-HDED PF07697.11 CBK25122.2 - 0.071 13.2 8.1 0.1 12.7 8.1 1.1 1 0 0 1 1 1 0 7TM-HD extracellular T4SS PF07996.11 CBK25122.2 - 0.076 13.4 12.5 0.12 12.8 11.3 1.9 1 1 1 2 2 2 0 Type IV secretion system proteins OmpH PF03938.14 CBK25122.2 - 0.098 13.0 9.3 0.15 12.4 9.3 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) RasGAP_C PF03836.15 CBK25122.2 - 0.19 11.9 3.2 0.49 10.5 3.2 1.6 1 1 0 1 1 1 0 RasGAP C-terminus Sec34 PF04136.15 CBK25122.2 - 0.2 11.5 2.3 0.31 10.9 2.3 1.3 1 0 0 1 1 1 0 Sec34-like family APG6_N PF17675.1 CBK25122.2 - 0.27 11.8 10.8 0.4 11.2 10.8 1.1 1 0 0 1 1 1 0 Apg6 coiled-coil region FlxA PF14282.6 CBK25122.2 - 0.3 11.1 9.9 0.56 10.2 9.9 1.4 1 0 0 1 1 1 0 FlxA-like protein Atg14 PF10186.9 CBK25122.2 - 0.4 9.7 4.7 0.54 9.3 4.7 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Muted PF14942.6 CBK25122.2 - 0.41 11.0 3.3 0.62 10.4 3.3 1.2 1 0 0 1 1 1 0 Organelle biogenesis, Muted-like protein ZnuA PF01297.17 CBK25122.2 - 0.58 9.5 2.4 0.79 9.1 2.4 1.1 1 0 0 1 1 1 0 Zinc-uptake complex component A periplasmic FUSC PF04632.12 CBK25122.2 - 0.9 8.0 14.4 0.067 11.7 9.6 1.4 2 0 0 2 2 2 0 Fusaric acid resistance protein family DUF724 PF05266.14 CBK25122.2 - 0.94 9.3 3.9 1.4 8.8 3.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF724) Phage_GP20 PF06810.11 CBK25122.2 - 1.2 9.0 7.3 1.9 8.3 7.3 1.3 1 0 0 1 1 1 0 Phage minor structural protein GP20 DUF4407 PF14362.6 CBK25122.2 - 1.8 7.9 9.6 2.5 7.3 9.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Alg6_Alg8 PF03155.15 CBK25123.2 - 5.8e-109 365.2 20.2 7.3e-109 364.9 20.2 1.0 1 0 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family Phage_holin_5_2 PF16079.5 CBK25124.2 - 0.013 15.8 2.3 0.013 15.8 2.3 2.1 1 1 1 2 2 2 0 Phage holin family Hol44, in holin superfamily V Glycos_transf_1 PF00534.20 CBK25125.2 - 9.1e-12 44.8 0.0 4.7e-11 42.5 0.0 1.9 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 CBK25125.2 - 2e-09 38.0 0.0 3.4e-09 37.2 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 CBK25125.2 - 1.6e-06 28.2 0.0 3e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.6 CBK25125.2 - 8.7e-06 26.3 0.0 4e-05 24.1 0.0 2.0 2 0 0 2 2 2 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.6 CBK25125.2 - 0.00056 20.2 0.0 0.0011 19.3 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_2 PF13477.6 CBK25125.2 - 0.032 14.3 0.0 0.071 13.1 0.0 1.6 1 0 0 1 1 1 0 Glycosyl transferase 4-like Fe_hyd_lg_C PF02906.14 CBK25126.2 - 1.5e-86 290.0 0.7 2.9e-86 289.1 0.7 1.5 1 0 0 1 1 1 1 Iron only hydrogenase large subunit, C-terminal domain Flavodoxin_1 PF00258.25 CBK25126.2 - 4.2e-33 114.6 0.4 8.6e-33 113.6 0.4 1.6 1 0 0 1 1 1 1 Flavodoxin Fe_hyd_SSU PF02256.17 CBK25126.2 - 2.1e-25 88.6 0.3 4.3e-25 87.6 0.3 1.6 1 0 0 1 1 1 1 Iron hydrogenase small subunit Fer2_4 PF13510.6 CBK25126.2 - 2.7e-18 65.8 0.3 9e-18 64.1 0.0 2.1 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fer2 PF00111.27 CBK25126.2 - 1.5e-08 34.5 0.4 1.5e-08 34.5 0.4 2.8 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fer4_21 PF14697.6 CBK25126.2 - 2.7e-06 27.4 6.2 1e-05 25.5 6.2 2.1 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_10 PF13237.6 CBK25126.2 - 7.1e-06 26.1 5.6 0.012 15.7 0.4 3.2 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_9 PF13187.6 CBK25126.2 - 1.7e-05 24.9 6.5 1.7e-05 24.9 6.5 3.2 3 1 1 4 4 3 2 4Fe-4S dicluster domain Fer4_16 PF13484.6 CBK25126.2 - 2.5e-05 25.1 12.4 0.00088 20.2 0.6 4.0 3 0 0 3 3 3 1 4Fe-4S double cluster binding domain Fer4 PF00037.27 CBK25126.2 - 3.3e-05 23.5 24.4 0.00024 20.8 3.0 4.0 4 0 0 4 4 3 2 4Fe-4S binding domain Fer4_7 PF12838.7 CBK25126.2 - 3.4e-05 24.4 19.7 0.00018 22.0 9.9 3.7 3 1 2 5 5 5 3 4Fe-4S dicluster domain Fer4_17 PF13534.6 CBK25126.2 - 0.00018 22.0 9.7 0.19 12.3 0.5 3.3 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_6 PF12837.7 CBK25126.2 - 0.0002 21.3 18.7 0.00051 20.0 1.0 3.4 3 0 0 3 3 2 2 4Fe-4S binding domain Flavodoxin_5 PF12724.7 CBK25126.2 - 0.00044 20.5 0.0 0.001 19.3 0.0 1.6 1 0 0 1 1 1 1 Flavodoxin domain Fer4_8 PF13183.6 CBK25126.2 - 0.00053 20.4 9.7 0.076 13.5 0.4 3.1 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_22 PF17179.4 CBK25126.2 - 0.0022 18.8 10.8 0.033 15.0 0.5 3.2 3 0 0 3 3 2 2 4Fe-4S dicluster domain Fer4_18 PF13746.6 CBK25126.2 - 0.067 13.4 6.1 1.2 9.4 0.7 2.9 2 0 0 2 2 2 0 4Fe-4S dicluster domain Fer4_15 PF13459.6 CBK25126.2 - 0.078 13.7 10.4 1.3 9.8 0.2 4.2 4 0 0 4 4 3 0 4Fe-4S single cluster domain Fer4_2 PF12797.7 CBK25126.2 - 0.086 13.0 17.1 0.23 11.6 1.6 3.6 3 0 0 3 3 2 0 4Fe-4S binding domain Flavodoxin_3 PF12641.7 CBK25126.2 - 0.13 11.9 0.1 0.54 9.9 0.0 2.0 2 0 0 2 2 2 0 Flavodoxin domain Fer4_13 PF13370.6 CBK25126.2 - 0.34 11.5 12.0 3 8.5 3.0 3.0 2 0 0 2 2 2 0 4Fe-4S single cluster domain of Ferredoxin I Fer4_4 PF12800.7 CBK25126.2 - 1.2 9.8 20.5 0.14 12.7 1.6 4.2 3 0 0 3 3 3 0 4Fe-4S binding domain WD40 PF00400.32 CBK25128.2 - 9.4e-46 152.9 25.1 4.8e-07 30.4 0.1 10.1 10 0 0 10 10 10 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBK25128.2 - 2.6e-12 46.9 4.1 0.00075 19.8 0.0 6.2 4 2 2 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 CBK25128.2 - 7.2e-08 31.5 16.0 0.22 10.1 0.1 7.3 4 3 3 8 8 8 4 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 CBK25128.2 - 0.00043 19.2 3.0 0.44 9.2 0.0 5.0 2 2 3 6 6 6 1 Nup133 N terminal like WD40_like PF17005.5 CBK25128.2 - 0.02 14.2 2.8 6 6.1 0.0 3.8 3 1 0 4 4 4 0 WD40-like domain VID27 PF08553.10 CBK25128.2 - 0.058 12.4 0.0 0.14 11.1 0.0 1.6 2 0 0 2 2 2 0 VID27 C-terminal WD40-like domain Flavokinase PF01687.17 CBK25129.2 - 3.8e-33 114.1 0.0 4.5e-33 113.9 0.0 1.0 1 0 0 1 1 1 1 Riboflavin kinase tRNA-synt_1c PF00749.21 CBK25131.2 - 5.4e-107 357.3 0.0 7.7e-107 356.8 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.18 CBK25131.2 - 3.5e-40 137.7 0.0 6.4e-40 136.9 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain tRNA_synt_1c_R1 PF04558.15 CBK25131.2 - 9.3e-24 84.3 0.3 4e-23 82.2 0.1 2.1 2 0 0 2 2 2 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 tRNA_synt_1c_R2 PF04557.15 CBK25131.2 - 3.4e-06 27.9 5.7 8.8e-06 26.6 5.7 1.7 1 0 0 1 1 1 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 2 CNDH2_N PF06278.11 CBK25132.2 - 8.7e-41 138.6 0.2 1.5e-40 137.9 0.2 1.4 1 0 0 1 1 1 1 Condensin II complex subunit CAP-H2 or CNDH2, N-terminal CNDH2_C PF16858.5 CBK25133.2 - 6.4e-38 131.3 0.6 7.5e-38 131.1 0.6 1.0 1 0 0 1 1 1 1 Condensin II complex subunit CAP-H2 or CNDH2, C-term CRA PF06589.11 CBK25133.2 - 0.015 15.4 1.1 0.018 15.1 1.1 1.2 1 0 0 1 1 1 0 Circumsporozoite-related antigen (CRA) GBP PF02263.19 CBK25135.2 - 1.7e-33 116.0 0.0 2.2e-33 115.6 0.0 1.1 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain He_PIG PF05345.12 CBK25136.2 - 1.4e-13 50.8 10.4 6.1e-05 23.1 1.1 5.0 3 0 0 3 3 3 3 Putative Ig domain PIF6 PF05341.11 CBK25136.2 - 0.24 11.5 0.0 0.24 11.5 0.0 2.5 2 0 0 2 2 2 0 Per os infectivity factor 6 Sushi PF00084.20 CBK25136.2 - 1.8 9.3 4.6 0.48 11.1 0.3 2.4 2 0 0 2 2 2 0 Sushi repeat (SCR repeat) RL10P_insert PF17777.1 CBK25137.2 - 2.8e-23 81.7 0.0 4.1e-23 81.2 0.0 1.3 1 0 0 1 1 1 1 Insertion domain in 60S ribosomal protein L10P Ribosomal_L10 PF00466.20 CBK25137.2 - 2.9e-19 69.1 0.0 4.2e-19 68.5 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L10 F-actin_cap_A PF01267.17 CBK25137.2 - 0.017 14.6 0.1 0.026 14.0 0.1 1.3 1 0 0 1 1 1 0 F-actin capping protein alpha subunit Histone PF00125.24 CBK25138.2 - 1.8e-17 63.9 0.1 2.1e-17 63.7 0.1 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 CBK25138.2 - 0.044 14.1 0.0 0.092 13.0 0.0 1.5 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 CBK25138.2 - 0.13 12.8 0.0 0.27 11.7 0.0 1.5 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A Histone_H2A_C PF16211.5 CBK25139.2 - 5.2e-15 54.9 0.0 9.3e-15 54.1 0.0 1.4 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 CBK25139.2 - 6.5e-13 49.2 0.0 9.9e-13 48.6 0.0 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 CBK25139.2 - 3e-05 24.2 0.0 4.3e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone GSHPx PF00255.19 CBK25140.2 - 1.5e-42 143.5 0.2 1.8e-42 143.3 0.2 1.1 1 0 0 1 1 1 1 Glutathione peroxidase AhpC-TSA PF00578.21 CBK25140.2 - 1.8e-05 24.6 0.0 2.6e-05 24.1 0.0 1.3 1 1 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 CBK25140.2 - 0.00013 21.7 0.0 0.00016 21.4 0.0 1.2 1 0 0 1 1 1 1 Redoxin CdiI_4 PF18624.1 CBK25140.2 - 0.0077 16.7 0.1 0.012 16.0 0.1 1.4 1 1 0 1 1 1 1 CDI immunity protein AHJR-like PF18743.1 CBK25140.2 - 0.11 12.1 0.1 0.18 11.4 0.1 1.3 1 0 0 1 1 1 0 REase_AHJR-like CPSase_L_D2 PF02786.17 CBK25141.2 - 7.4e-108 358.9 0.0 2.5e-80 268.9 0.0 2.3 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_sm_chain PF00988.22 CBK25141.2 - 4.5e-52 175.2 0.0 9e-52 174.3 0.0 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain GATase PF00117.28 CBK25141.2 - 8.4e-48 162.7 0.0 1.9e-47 161.5 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase class-I CPSase_L_D3 PF02787.19 CBK25141.2 - 4.2e-35 120.7 0.1 1.2e-34 119.3 0.0 1.9 2 0 0 2 2 2 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain Dala_Dala_lig_C PF07478.13 CBK25141.2 - 4e-15 55.9 0.1 2.3e-06 27.3 0.0 2.6 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 CBK25141.2 - 1.7e-13 50.5 0.0 3.4e-08 33.2 0.0 2.3 2 0 0 2 2 2 2 ATP-grasp domain MGS PF02142.22 CBK25141.2 - 2.8e-13 49.9 0.1 1.8e-12 47.3 0.0 2.5 2 0 0 2 2 1 1 MGS-like domain ATPgrasp_Ter PF15632.6 CBK25141.2 - 3.9e-12 46.0 0.1 6.9e-05 22.6 0.0 2.5 2 0 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp_3 PF02655.14 CBK25141.2 - 8.4e-07 29.2 0.1 0.0076 16.3 0.0 2.9 3 1 0 3 3 3 2 ATP-grasp domain DJ-1_PfpI PF01965.24 CBK25141.2 - 5.3e-06 26.3 0.1 0.02 14.7 0.0 3.4 3 0 0 3 3 3 1 DJ-1/PfpI family RimK PF08443.11 CBK25141.2 - 0.0001 22.0 0.0 0.051 13.2 0.0 2.6 2 0 0 2 2 2 2 RimK-like ATP-grasp domain Peptidase_C26 PF07722.13 CBK25141.2 - 0.00012 22.0 0.0 0.0011 18.8 0.0 2.2 1 1 0 1 1 1 1 Peptidase C26 ATP-grasp_5 PF13549.6 CBK25141.2 - 0.0046 16.4 0.0 2.2 7.7 0.0 2.5 2 0 0 2 2 2 2 ATP-grasp domain GARS_A PF01071.19 CBK25141.2 - 0.084 12.6 0.0 0.42 10.3 0.0 2.1 2 0 0 2 2 2 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain MTP18 PF10558.9 CBK25141.2 - 0.1 12.5 0.0 0.29 11.1 0.0 1.7 1 0 0 1 1 1 0 Mitochondrial 18 KDa protein (MTP18) Fe-ADH PF00465.19 CBK25142.2 - 7e-74 248.8 0.0 8.6e-74 248.5 0.0 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.6 CBK25142.2 - 0.00017 21.4 0.0 0.0012 18.6 0.0 2.0 2 0 0 2 2 2 1 Iron-containing alcohol dehydrogenase CbiK PF06180.11 CBK25142.2 - 0.025 13.9 0.1 0.063 12.6 0.0 1.6 2 0 0 2 2 2 0 Cobalt chelatase (CbiK) UPF0139 PF03669.13 CBK25143.2 - 1e-11 44.5 0.4 1.1e-11 44.4 0.4 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0139) HGTP_anticodon PF03129.20 CBK25144.2 - 2.5e-19 69.2 0.1 1.5e-18 66.8 0.0 2.0 2 0 0 2 2 2 1 Anticodon binding domain HSP70 PF00012.20 CBK25145.2 - 3.5e-13 48.6 0.0 4.9e-13 48.1 0.0 1.2 1 0 0 1 1 1 1 Hsp70 protein Fe-ADH PF00465.19 CBK25146.2 - 3.4e-74 249.9 0.0 4.1e-74 249.6 0.0 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.6 CBK25146.2 - 0.00016 21.5 0.1 0.0017 18.1 0.0 2.1 2 0 0 2 2 2 1 Iron-containing alcohol dehydrogenase CbiK PF06180.11 CBK25146.2 - 0.026 13.8 0.0 0.064 12.6 0.0 1.6 1 0 0 1 1 1 0 Cobalt chelatase (CbiK) DHQ_synthase PF01761.20 CBK25146.2 - 0.058 12.5 0.1 0.26 10.4 0.1 1.9 2 0 0 2 2 2 0 3-dehydroquinate synthase Ribosomal_L4 PF00573.22 CBK25149.2 - 1.7e-39 135.5 0.1 3.2e-39 134.6 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Ribos_L4_asso_C PF14374.6 CBK25149.2 - 1e-22 80.0 1.6 4.2e-22 78.0 1.5 2.1 2 0 0 2 2 2 1 60S ribosomal protein L4 C-terminal domain Ribonuc_P_40 PF08584.11 CBK25149.2 - 0.051 12.8 0.0 0.11 11.8 0.0 1.4 1 0 0 1 1 1 0 Ribonuclease P 40kDa (Rpp40) subunit Ribosomal_L2_C PF03947.18 CBK25150.2 - 1.4e-45 154.6 1.6 2.1e-45 154.0 1.6 1.2 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 CBK25150.2 - 1.2e-14 54.0 0.1 3.4e-14 52.6 0.0 1.9 2 0 0 2 2 2 1 Ribosomal Proteins L2, RNA binding domain Mtc PF03820.17 CBK25151.2 - 2.8e-101 338.7 0.0 3.2e-101 338.5 0.0 1.0 1 0 0 1 1 1 1 Tricarboxylate carrier Ribosomal_S19 PF00203.21 CBK25152.2 - 6.1e-34 115.8 0.2 7.4e-34 115.5 0.2 1.1 1 0 0 1 1 1 1 Ribosomal protein S19 Vps53_N PF04100.12 CBK25153.2 - 9.5e-70 235.5 7.7 2e-68 231.1 7.7 2.1 1 1 0 1 1 1 1 Vps53-like, N-terminal Sec6 PF06046.13 CBK25153.2 - 3.2e-06 25.8 0.2 3.2e-06 25.8 0.2 2.8 4 0 0 4 4 4 1 Exocyst complex component Sec6 Vps54_N PF10475.9 CBK25153.2 - 0.00034 20.0 6.2 0.00085 18.7 5.3 2.0 2 0 0 2 2 2 1 Vacuolar-sorting protein 54, of GARP complex Laminin_II PF06009.12 CBK25153.2 - 0.0015 18.5 4.8 0.0032 17.5 3.9 2.0 1 1 0 1 1 1 1 Laminin Domain II DUF2451 PF10474.9 CBK25153.2 - 0.0058 16.4 3.7 0.011 15.5 0.3 3.0 2 2 0 2 2 2 1 Protein of unknown function C-terminus (DUF2451) Spc7 PF08317.11 CBK25153.2 - 0.01 14.7 7.8 0.024 13.6 7.8 1.6 1 0 0 1 1 1 0 Spc7 kinetochore protein Laminin_I PF06008.14 CBK25153.2 - 0.018 14.7 5.2 0.058 13.1 5.2 1.8 1 0 0 1 1 1 0 Laminin Domain I DUF2884 PF11101.8 CBK25153.2 - 0.022 14.3 4.1 0.081 12.4 4.1 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2884) Leu_zip PF15294.6 CBK25153.2 - 0.056 13.0 4.8 0.15 11.5 4.8 1.8 1 0 0 1 1 1 0 Leucine zipper XhlA PF10779.9 CBK25153.2 - 0.087 13.0 8.8 0.042 14.0 2.7 3.2 3 0 0 3 3 3 0 Haemolysin XhlA Sec5 PF15469.6 CBK25153.2 - 0.61 9.9 3.8 1.5 8.6 3.8 1.7 1 1 0 1 1 1 0 Exocyst complex component Sec5 DUF948 PF06103.11 CBK25153.2 - 0.69 10.2 2.5 1.6 9.0 1.0 2.5 2 1 0 2 2 1 0 Bacterial protein of unknown function (DUF948) ING PF12998.7 CBK25153.2 - 0.7 10.5 4.9 1.8 9.2 4.9 1.8 1 0 0 1 1 1 0 Inhibitor of growth proteins N-terminal histone-binding Atg14 PF10186.9 CBK25153.2 - 1.2 8.2 6.2 2 7.4 6.2 1.4 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 SKA2 PF16740.5 CBK25153.2 - 4.3 7.2 10.2 7.8 6.3 2.4 4.0 4 1 1 5 5 5 0 Spindle and kinetochore-associated protein 2 DUF1664 PF07889.12 CBK25153.2 - 9.1 6.3 7.6 22 5.1 5.2 2.9 3 1 0 3 3 3 0 Protein of unknown function (DUF1664) HSP70 PF00012.20 CBK25154.2 - 9.9e-52 175.9 0.0 1.2e-51 175.6 0.0 1.1 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 CBK25154.2 - 7.2e-17 61.2 0.0 2.6e-16 59.4 0.0 1.7 2 0 0 2 2 2 1 MreB/Mbl protein FtsA PF14450.6 CBK25154.2 - 0.00012 22.4 0.1 0.0079 16.6 0.0 2.9 2 1 0 2 2 2 1 Cell division protein FtsA AbiTii PF18864.1 CBK25154.2 - 0.00057 20.1 0.6 0.0011 19.1 0.1 1.8 2 0 0 2 2 2 1 AbiTii StbA PF06406.11 CBK25154.2 - 0.0011 18.2 0.0 0.0022 17.3 0.0 1.4 1 0 0 1 1 1 1 StbA protein Actin PF00022.19 CBK25154.2 - 0.014 14.0 0.0 0.16 10.5 0.0 2.0 1 1 1 2 2 2 0 Actin PilM_2 PF11104.8 CBK25154.2 - 0.078 12.0 0.1 1.7 7.6 0.0 2.5 2 1 1 3 3 3 0 Type IV pilus assembly protein PilM; Ribosomal_S19 PF00203.21 CBK25155.2 - 9.7e-34 115.1 0.2 1.4e-33 114.6 0.2 1.2 1 0 0 1 1 1 1 Ribosomal protein S19 Ribosomal_L27e PF01777.18 CBK25156.2 - 7.7e-21 74.2 7.0 1.1e-20 73.7 7.0 1.2 1 0 0 1 1 1 1 Ribosomal L27e protein family KOW PF00467.29 CBK25156.2 - 5.3e-06 26.2 1.0 9.5e-06 25.4 1.0 1.4 1 0 0 1 1 1 1 KOW motif zf-LYAR PF08790.11 CBK25157.2 - 1.9e-13 50.1 1.7 1.9e-13 50.1 1.7 2.1 2 0 0 2 2 2 1 LYAR-type C2HC zinc finger zf_UBZ PF18439.1 CBK25157.2 - 3.5e-05 23.3 0.4 0.033 13.8 0.1 2.4 2 0 0 2 2 2 2 Ubiquitin-Binding Zinc Finger NPM1-C PF16276.5 CBK25157.2 - 0.0038 17.2 0.5 0.0097 15.9 0.5 1.7 1 0 0 1 1 1 1 Nucleophosmin C-terminal domain Zn-ribbon_8 PF09723.10 CBK25157.2 - 1.5 9.0 5.5 8.4 6.6 0.3 2.5 1 1 1 2 2 2 0 Zinc ribbon domain NAD_binding_2 PF03446.15 CBK25159.2 - 9.6e-46 155.8 0.9 2.5e-45 154.5 0.9 1.7 1 1 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 CBK25159.2 - 1.2e-35 122.4 0.1 2e-35 121.7 0.1 1.4 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.17 CBK25159.2 - 3.9e-11 43.4 0.1 7.6e-11 42.5 0.1 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.20 CBK25159.2 - 1.1e-07 32.1 0.0 2e-07 31.2 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase 2-Hacid_dh_C PF02826.19 CBK25159.2 - 1.2e-05 24.7 0.0 2.1e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.12 CBK25159.2 - 8.7e-05 22.1 0.0 0.00019 21.0 0.0 1.5 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain Sacchrp_dh_NADP PF03435.18 CBK25159.2 - 0.0057 16.9 0.0 0.16 12.2 0.0 2.2 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain ApbA PF02558.16 CBK25159.2 - 0.0073 16.0 0.0 0.012 15.3 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA 3HCDH_N PF02737.18 CBK25159.2 - 0.01 15.7 0.1 0.017 15.0 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain TrkA_N PF02254.18 CBK25159.2 - 0.012 15.9 0.0 0.023 14.9 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain NAD_binding_7 PF13241.6 CBK25159.2 - 0.025 15.0 0.0 0.06 13.8 0.0 1.7 1 1 0 1 1 1 0 Putative NAD(P)-binding adh_short PF00106.25 CBK25159.2 - 0.048 13.1 0.1 0.094 12.2 0.1 1.4 1 0 0 1 1 1 0 short chain dehydrogenase STT3 PF02516.14 CBK25160.2 - 5.6e-92 309.2 48.8 9.2e-91 305.2 48.8 2.0 1 1 0 1 1 1 1 Oligosaccharyl transferase STT3 subunit TRAUB PF08164.12 CBK25161.2 - 8.1e-18 64.7 0.3 1.7e-17 63.7 0.3 1.6 1 0 0 1 1 1 1 Apoptosis-antagonizing transcription factor, C-terminal Prenyltrans PF00432.21 CBK25162.2 - 4.3e-63 208.7 14.0 7.5e-14 51.2 0.1 6.2 6 0 0 6 6 6 5 Prenyltransferase and squalene oxidase repeat SQHop_cyclase_N PF13249.6 CBK25162.2 - 4.9e-06 25.8 0.0 0.0094 15.1 0.0 3.1 1 1 1 3 3 3 2 Squalene-hopene cyclase N-terminal domain SQHop_cyclase_C PF13243.6 CBK25162.2 - 1.7e-05 24.1 0.0 0.11 11.6 0.2 2.8 1 1 2 3 3 3 2 Squalene-hopene cyclase C-terminal domain Mito_carr PF00153.27 CBK25163.2 - 4.5e-36 122.7 1.3 3.5e-23 81.3 0.1 2.9 3 0 0 3 3 3 2 Mitochondrial carrier protein Xpo1 PF08389.12 CBK25164.2 - 1.5 8.9 11.2 0.23 11.5 2.7 3.4 2 2 2 4 4 4 0 Exportin 1-like protein Thioredoxin PF00085.20 CBK25165.2 - 5.3e-05 23.1 0.0 9.3e-05 22.4 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin OST3_OST6 PF04756.13 CBK25165.2 - 0.0012 18.2 0.0 0.0021 17.5 0.0 1.3 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family DUF836 PF05768.14 CBK25165.2 - 0.033 14.6 0.1 5.5 7.5 0.0 2.3 2 0 0 2 2 2 0 Glutaredoxin-like domain (DUF836) Thioredoxin_8 PF13905.6 CBK25165.2 - 0.054 13.8 0.1 0.23 11.8 0.0 2.1 2 2 0 2 2 2 0 Thioredoxin-like Thioredoxin PF00085.20 CBK25166.2 - 0.00052 20.0 0.0 0.00058 19.8 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin OST3_OST6 PF04756.13 CBK25166.2 - 0.0011 18.4 0.3 0.0013 18.2 0.3 1.0 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Glyco_hydro_47 PF01532.20 CBK25167.2 - 3e-106 356.1 0.0 4.5e-106 355.5 0.0 1.3 1 1 0 1 1 1 1 Glycosyl hydrolase family 47 WD40 PF00400.32 CBK25168.2 - 5.1e-19 68.3 1.3 1.3e-06 29.0 0.0 6.4 7 0 0 7 7 7 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBK25168.2 - 1.5e-12 47.6 0.4 5.6e-05 23.3 0.2 4.3 2 1 2 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain LisH PF08513.11 CBK25168.2 - 1.1e-10 41.0 0.1 2.2e-10 40.1 0.1 1.5 1 0 0 1 1 1 1 LisH MIase PF02426.16 CBK25168.2 - 0.079 13.1 0.0 0.2 11.8 0.0 1.6 1 0 0 1 1 1 0 Muconolactone delta-isomerase Ribosomal_L26 PF16906.5 CBK25169.2 - 8.1e-19 67.9 0.5 1.1e-18 67.5 0.5 1.2 1 0 0 1 1 1 1 Ribosomal proteins L26 eukaryotic, L24P archaeal KOW PF00467.29 CBK25169.2 - 9.3e-10 38.1 3.0 1.9e-09 37.1 3.0 1.7 1 1 0 1 1 1 1 KOW motif Takusan PF04822.13 CBK25170.2 - 0.11 12.4 0.8 0.11 12.4 0.8 2.3 3 0 0 3 3 3 0 Takusan TPR_8 PF13181.6 CBK25171.2 - 5.5e-11 41.8 1.7 3.1e-07 30.1 0.1 3.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 CBK25171.2 - 2.7e-10 39.5 0.3 1.5e-06 27.9 0.0 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 CBK25171.2 - 5.7e-10 38.6 1.1 7.5e-08 31.9 0.1 2.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 CBK25171.2 - 4.2e-07 29.5 0.4 0.011 15.7 0.0 4.1 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.6 CBK25171.2 - 3.5e-05 24.0 0.6 0.00033 20.9 0.1 2.7 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.6 CBK25171.2 - 0.009 16.3 0.2 1.2 9.7 0.1 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.6 CBK25171.2 - 0.024 15.2 0.4 2.1 9.2 0.0 3.3 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_11 PF13414.6 CBK25171.2 - 0.046 13.4 1.1 0.55 10.0 0.2 2.7 3 0 0 3 3 3 0 TPR repeat TPR_14 PF13428.6 CBK25171.2 - 0.048 14.5 0.0 4.7 8.3 0.0 3.3 2 2 2 4 4 4 0 Tetratricopeptide repeat zf-CCCH PF00642.24 CBK25172.2 - 2.6e-07 30.4 10.6 0.00045 20.1 1.6 2.6 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 CBK25172.2 - 0.00022 21.9 9.8 0.0039 17.9 2.1 3.0 2 1 0 2 2 2 2 Torus domain zf-CCCH_4 PF18044.1 CBK25172.2 - 0.0069 16.2 5.1 0.0069 16.2 5.1 2.9 2 0 0 2 2 2 1 CCCH-type zinc finger CBFD_NFYB_HMF PF00808.23 CBK25174.2 - 1.6e-14 53.9 1.6 1.9e-14 53.6 0.6 1.7 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 CBK25174.2 - 2.7e-08 34.2 0.5 3.1e-08 34.1 0.5 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TAFII28 PF04719.14 CBK25174.2 - 0.089 12.9 0.1 0.12 12.5 0.1 1.2 1 0 0 1 1 1 0 hTAFII28-like protein conserved region Fumerase PF05681.14 CBK25175.2 - 6.2e-89 298.0 0.0 9.8e-89 297.4 0.0 1.3 1 0 0 1 1 1 1 Fumarate hydratase (Fumerase) Fumerase_C PF05683.12 CBK25175.2 - 5.5e-87 290.4 0.0 8.8e-87 289.7 0.0 1.3 1 0 0 1 1 1 1 Fumarase C-terminus MMR_HSR1_Xtn PF16897.5 CBK25177.2 - 9.1e-38 128.5 0.3 2e-37 127.4 0.3 1.6 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain MMR_HSR1 PF01926.23 CBK25177.2 - 4.4e-20 71.9 0.0 1.2e-19 70.5 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase TGS PF02824.21 CBK25177.2 - 3.8e-15 55.7 0.0 7.2e-15 54.8 0.0 1.5 1 0 0 1 1 1 1 TGS domain FeoB_N PF02421.18 CBK25177.2 - 1.4e-09 37.6 0.0 2.8e-09 36.7 0.0 1.5 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 CBK25177.2 - 5.4e-05 23.3 0.2 0.02 14.9 0.0 2.7 3 0 0 3 3 3 2 Dynamin family GPAT_N PF14829.6 CBK25177.2 - 0.035 14.1 0.2 0.078 13.0 0.2 1.5 1 0 0 1 1 1 0 Glycerol-3-phosphate acyltransferase N-terminal Roc PF08477.13 CBK25177.2 - 0.05 13.8 0.0 0.29 11.4 0.0 2.3 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase AAA_28 PF13521.6 CBK25177.2 - 0.051 13.8 0.1 0.27 11.5 0.1 2.2 2 0 0 2 2 2 0 AAA domain Proteasome PF00227.26 CBK25178.2 - 1.3e-52 178.0 0.0 1.6e-52 177.8 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 CBK25178.2 - 5.2e-14 51.6 0.2 1e-13 50.6 0.2 1.5 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature DUF3842 PF12953.7 CBK25178.2 - 0.097 13.1 0.5 1.4 9.3 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3842) WD40 PF00400.32 CBK25179.2 - 3e-10 40.5 0.2 0.00082 20.1 0.0 3.4 3 0 0 3 3 3 2 WD domain, G-beta repeat Ge1_WD40 PF16529.5 CBK25179.2 - 0.031 13.3 0.0 0.039 12.9 0.0 1.2 1 0 0 1 1 1 0 WD40 region of Ge1, enhancer of mRNA-decapping protein ANAPC4_WD40 PF12894.7 CBK25179.2 - 0.036 14.4 0.1 0.073 13.4 0.1 1.7 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 CBK25179.2 - 0.056 12.8 0.0 0.067 12.5 0.0 1.1 1 0 0 1 1 1 0 WD40-like domain ThiF PF00899.21 CBK25180.2 - 1.6e-67 227.4 0.0 2e-67 227.1 0.0 1.0 1 0 0 1 1 1 1 ThiF family Shikimate_DH PF01488.20 CBK25180.2 - 0.0011 19.1 0.1 0.0022 18.1 0.1 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.6 CBK25180.2 - 0.0018 18.7 0.1 0.0034 17.8 0.1 1.4 1 0 0 1 1 1 1 Putative NAD(P)-binding UBA_e1_thiolCys PF10585.9 CBK25180.2 - 0.021 14.8 0.0 0.069 13.1 0.0 1.8 1 1 0 1 1 1 0 Ubiquitin-activating enzyme active site Pyr_redox PF00070.27 CBK25180.2 - 0.026 15.1 0.8 0.31 11.6 0.1 2.7 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.18 CBK25180.2 - 0.11 12.8 0.1 0.2 11.9 0.1 1.5 1 0 0 1 1 1 0 TrkA-N domain Sacchrp_dh_NADP PF03435.18 CBK25180.2 - 0.29 11.4 1.2 1.5 9.0 1.2 2.1 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain HRDC PF00570.23 CBK25181.2 - 8.1e-12 45.0 0.0 1.8e-11 43.8 0.0 1.7 1 0 0 1 1 1 1 HRDC domain AFG1_ATPase PF03969.16 CBK25183.2 - 1.8e-94 316.6 0.1 1.7e-93 313.4 0.1 1.9 1 1 1 2 2 2 1 AFG1-like ATPase AAA PF00004.29 CBK25183.2 - 1.6e-08 35.0 0.0 5.8e-08 33.2 0.0 2.0 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 CBK25183.2 - 5.2e-05 23.7 0.0 0.087 13.2 0.0 2.4 1 1 0 2 2 2 2 AAA ATPase domain AAA_14 PF13173.6 CBK25183.2 - 0.00036 20.6 0.0 0.0016 18.5 0.0 2.0 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 CBK25183.2 - 0.0016 18.8 0.1 0.0064 16.9 0.0 2.1 2 1 0 2 2 2 1 RNA helicase PEPCK_N PF17297.2 CBK25183.2 - 0.0023 17.6 0.0 0.013 15.1 0.0 2.0 1 1 1 2 2 2 1 Phosphoenolpyruvate carboxykinase N-terminal domain UvrD-helicase PF00580.21 CBK25183.2 - 0.0032 17.0 0.2 0.012 15.2 0.1 1.7 1 1 1 2 2 2 1 UvrD/REP helicase N-terminal domain Bac_DnaA PF00308.18 CBK25183.2 - 0.004 17.0 0.5 0.056 13.3 0.0 2.4 2 1 0 2 2 2 1 Bacterial dnaA protein Sigma54_activ_2 PF14532.6 CBK25183.2 - 0.0045 17.1 0.0 1.9 8.6 0.0 2.8 2 1 0 2 2 2 1 Sigma-54 interaction domain AAA_22 PF13401.6 CBK25183.2 - 0.0058 16.9 0.0 0.023 15.0 0.0 2.0 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.6 CBK25183.2 - 0.011 16.1 0.1 0.75 10.1 0.0 2.4 1 1 1 2 2 2 0 AAA domain NACHT PF05729.12 CBK25183.2 - 0.011 15.6 0.0 0.16 11.9 0.0 2.6 2 1 0 2 2 2 0 NACHT domain Zeta_toxin PF06414.12 CBK25183.2 - 0.13 11.5 0.0 0.27 10.5 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin ABC_tran PF00005.27 CBK25183.2 - 0.15 12.6 0.0 1.9 9.0 0.0 2.2 1 1 1 2 2 2 0 ABC transporter Mcl1_mid PF12341.8 CBK25184.2 - 1.5e-30 106.6 0.0 4.5e-30 105.0 0.0 1.8 2 0 0 2 2 2 1 Minichromosome loss protein, Mcl1, middle region ANAPC4_WD40 PF12894.7 CBK25184.2 - 3.7e-05 24.0 0.0 0.025 14.9 0.0 3.6 1 1 2 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 CBK25184.2 - 6.6e-05 23.6 4.0 0.00022 21.9 0.1 3.7 4 0 0 4 4 4 1 WD domain, G-beta repeat Nup160 PF11715.8 CBK25184.2 - 0.00021 20.1 0.0 0.0015 17.3 0.0 2.0 2 0 0 2 2 2 1 Nucleoporin Nup120/160 Hira PF07569.11 CBK25184.2 - 0.11 12.2 1.0 0.49 10.1 0.0 2.3 3 0 0 3 3 3 0 TUP1-like enhancer of split Tnp_22_trimer PF17489.2 CBK25185.2 - 0.073 13.1 0.5 0.073 13.1 0.5 2.2 1 1 1 2 2 2 0 L1 transposable element trimerization domain PIF1 PF05970.14 CBK25186.2 - 2.5e-57 194.7 0.6 1.8e-43 149.1 0.2 2.3 1 1 0 2 2 2 2 PIF1-like helicase AAA_30 PF13604.6 CBK25186.2 - 5.8e-19 68.6 0.0 1e-18 67.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 CBK25186.2 - 2e-10 41.1 0.0 3.8e-10 40.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 CBK25186.2 - 2.2e-05 24.7 0.0 0.00017 21.9 0.0 2.4 3 0 0 3 3 3 1 AAA domain AAA PF00004.29 CBK25186.2 - 0.00022 21.6 0.0 0.00051 20.5 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Helicase_RecD PF05127.14 CBK25186.2 - 0.00049 20.0 0.0 0.0011 18.8 0.0 1.6 1 1 0 1 1 1 1 Helicase DUF2075 PF09848.9 CBK25186.2 - 0.018 14.3 0.0 0.035 13.4 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Herpes_Helicase PF02689.14 CBK25186.2 - 0.035 12.0 0.2 1.2 6.9 0.0 2.1 2 0 0 2 2 2 0 Helicase AAA_16 PF13191.6 CBK25186.2 - 0.041 14.3 1.4 0.084 13.3 0.0 2.2 3 0 0 3 3 3 0 AAA ATPase domain Viral_helicase1 PF01443.18 CBK25186.2 - 0.057 13.2 0.0 0.13 12.0 0.0 1.6 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase NTPase_1 PF03266.15 CBK25186.2 - 0.087 12.7 0.1 5.4 6.9 0.0 2.4 2 0 0 2 2 2 0 NTPase NACHT PF05729.12 CBK25186.2 - 0.12 12.3 0.0 0.23 11.3 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA_24 PF13479.6 CBK25186.2 - 0.18 11.5 0.0 0.33 10.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain Aminotran_5 PF00266.19 CBK25187.2 - 1.7e-43 149.0 0.0 1.8e-42 145.7 0.0 2.0 1 1 0 1 1 1 1 Aminotransferase class-V ATP_bind_3 PF01171.20 CBK25187.2 - 9.4e-20 71.1 0.0 2.2e-19 69.9 0.0 1.6 1 0 0 1 1 1 1 PP-loop family DUF3801 PF12687.7 CBK25187.2 - 0.027 14.5 5.2 0.53 10.3 4.6 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3801) zf-XS PF03470.14 CBK25187.2 - 0.028 14.7 0.1 0.29 11.4 0.2 2.3 2 0 0 2 2 2 0 XS zinc finger domain Sporozoite_P67 PF05642.11 CBK25187.2 - 0.11 10.6 4.5 0.17 9.9 4.5 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen HPD PF05044.12 CBK25187.2 - 0.15 11.9 0.1 0.26 11.1 0.1 1.3 1 0 0 1 1 1 0 Homeo-prospero domain SAPS PF04499.15 CBK25187.2 - 0.67 8.7 3.3 1 8.0 3.3 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Lin-8 PF03353.15 CBK25187.2 - 1.6 8.2 6.6 2.7 7.5 6.6 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Spt20 PF12090.8 CBK25187.2 - 1.9 8.1 13.8 3 7.4 13.8 1.2 1 0 0 1 1 1 0 Spt20 family Tim54 PF11711.8 CBK25187.2 - 1.9 7.2 7.8 3 6.5 7.8 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 SRP-alpha_N PF04086.13 CBK25187.2 - 2.5 7.9 13.1 5 7.0 13.1 1.4 1 1 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal RR_TM4-6 PF06459.12 CBK25187.2 - 3.7 7.3 10.3 6 6.6 10.3 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Coilin_N PF15862.5 CBK25187.2 - 6.5 6.6 11.5 22 4.8 0.0 2.3 2 0 0 2 2 2 0 Coilin N-terminus CPSF100_C PF13299.6 CBK25187.2 - 9.6 6.4 6.9 20 5.3 6.9 1.4 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Trypan_PARP PF05887.11 CBK25187.2 - 9.7 6.2 12.1 22 5.1 12.1 1.5 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) SNARE PF05739.19 CBK25188.2 - 1.4e-05 24.9 0.4 2.1e-05 24.4 0.4 1.2 1 0 0 1 1 1 1 SNARE domain GDP_Man_Dehyd PF16363.5 CBK25189.2 - 3.3e-55 187.8 0.0 3.8e-54 184.3 0.0 2.4 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 CBK25189.2 - 3.4e-49 167.5 0.0 4.2e-49 167.2 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 CBK25189.2 - 3.4e-08 32.9 0.0 4.4e-08 32.6 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain 3Beta_HSD PF01073.19 CBK25189.2 - 6.6e-07 28.6 0.0 2.5e-06 26.7 0.0 1.8 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 CBK25189.2 - 1.9e-06 27.3 0.0 0.00064 19.0 0.0 2.5 2 1 0 2 2 2 2 Male sterility protein Polysacc_synt_2 PF02719.15 CBK25189.2 - 0.0022 17.2 0.0 0.88 8.6 0.0 2.5 2 1 0 2 2 2 2 Polysaccharide biosynthesis protein UDPG_MGDP_dh_N PF03721.14 CBK25189.2 - 0.0043 16.6 0.7 0.0071 15.9 0.7 1.3 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Rad1 PF02144.16 CBK25190.2 - 7.2e-13 48.2 3.7 1.2e-12 47.5 3.7 1.4 1 1 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 PCNA_N PF00705.18 CBK25190.2 - 0.0019 17.9 1.1 0.0026 17.5 1.1 1.2 1 0 0 1 1 1 1 Proliferating cell nuclear antigen, N-terminal domain MMR_HSR1_Xtn PF16897.5 CBK25190.2 - 0.065 13.3 0.1 0.17 11.9 0.1 1.6 2 0 0 2 2 2 0 C-terminal region of MMR_HSR1 domain TLD PF07534.16 CBK25191.2 - 4.5e-16 59.3 0.0 6.7e-16 58.8 0.0 1.2 1 0 0 1 1 1 1 TLD Metallophos PF00149.28 CBK25192.2 - 1.1e-36 127.2 0.0 1.4e-36 126.9 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Tom22 PF04281.13 CBK25193.2 - 0.00023 21.0 0.0 0.00028 20.7 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial import receptor subunit Tom22 HSP70 PF00012.20 CBK25194.2 - 2.1e-12 46.1 0.2 5.8e-07 28.1 0.0 2.8 3 1 0 3 3 3 2 Hsp70 protein FF PF01846.19 CBK25195.2 - 5.5e-20 71.3 0.2 9.2e-09 35.4 0.0 5.0 5 0 0 5 5 5 3 FF domain WW PF00397.26 CBK25195.2 - 5.4e-11 42.4 10.3 1e-05 25.5 1.6 2.8 2 0 0 2 2 2 2 WW domain RhoGAP-FF1 PF16512.5 CBK25195.2 - 0.024 15.3 2.3 0.19 12.4 0.0 3.2 2 1 1 3 3 3 0 p190-A and -B Rho GAPs FF domain TFIIA PF03153.13 CBK25195.2 - 0.17 11.9 7.3 0.34 10.9 7.3 1.5 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Histone_HNS PF00816.21 CBK25195.2 - 1.3 9.9 16.3 19 6.1 0.2 4.6 3 1 0 3 3 3 0 H-NS histone family AhpC-TSA PF00578.21 CBK25198.2 - 5.4e-44 149.1 0.2 5.1e-37 126.6 0.0 2.2 2 0 0 2 2 2 2 AhpC/TSA family Thioredoxin PF00085.20 CBK25198.2 - 1e-25 89.7 0.7 1.8e-25 88.9 0.7 1.4 1 0 0 1 1 1 1 Thioredoxin Redoxin PF08534.10 CBK25198.2 - 2.3e-19 69.6 0.2 1.3e-14 54.2 0.0 2.1 2 0 0 2 2 2 2 Redoxin 1-cysPrx_C PF10417.9 CBK25198.2 - 5e-12 45.5 0.0 1.2e-11 44.3 0.0 1.7 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin Thioredoxin_9 PF14595.6 CBK25198.2 - 2.9e-06 27.1 0.0 5.1e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 CBK25198.2 - 4.3e-06 27.0 0.0 0.003 17.9 0.1 2.5 2 0 0 2 2 2 2 Thioredoxin-like Thioredoxin_2 PF13098.6 CBK25198.2 - 5.1e-06 26.9 0.5 2e-05 25.0 0.1 2.1 2 0 0 2 2 2 1 Thioredoxin-like domain OST3_OST6 PF04756.13 CBK25198.2 - 0.0081 15.5 0.1 0.013 14.9 0.1 1.2 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family SCO1-SenC PF02630.14 CBK25198.2 - 0.019 14.9 0.3 0.22 11.4 0.1 2.3 2 0 0 2 2 2 0 SCO1/SenC Thioredoxin_7 PF13899.6 CBK25198.2 - 0.025 14.8 0.0 0.065 13.4 0.0 1.7 1 0 0 1 1 1 0 Thioredoxin-like Thioredoxin_5 PF13743.6 CBK25198.2 - 0.028 14.1 0.1 0.22 11.2 0.0 2.0 1 1 1 2 2 2 0 Thioredoxin Metallophos PF00149.28 CBK25199.2 - 1e-14 55.5 2.6 1.4e-14 55.1 2.6 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 CBK25199.2 - 3.2e-06 27.4 0.0 1.7e-05 25.1 0.1 2.0 2 1 0 2 2 2 1 Calcineurin-like phosphoesterase superfamily domain Metallophos_3 PF14582.6 CBK25199.2 - 0.099 11.9 0.0 0.37 10.1 0.0 1.8 2 0 0 2 2 2 0 Metallophosphoesterase, calcineurin superfamily Arf PF00025.21 CBK25201.2 - 2.9e-72 241.8 0.0 3.5e-72 241.5 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 CBK25201.2 - 4.2e-13 49.6 0.0 5.6e-13 49.2 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase G-alpha PF00503.20 CBK25201.2 - 1.6e-12 47.3 0.4 1.6e-08 34.2 0.2 2.5 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.22 CBK25201.2 - 2.2e-12 46.9 0.0 2.6e-12 46.7 0.0 1.0 1 0 0 1 1 1 1 Ras family SRPRB PF09439.10 CBK25201.2 - 3.9e-12 46.0 0.0 4.7e-12 45.7 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 CBK25201.2 - 4.6e-09 36.0 0.0 5.7e-09 35.7 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 CBK25201.2 - 1.5e-05 25.0 0.0 4.1e-05 23.6 0.0 1.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 CBK25201.2 - 0.0039 16.7 0.6 0.016 14.8 0.6 1.9 1 1 0 1 1 1 1 Ferrous iron transport protein B Adap_comp_sub PF00928.21 CBK25202.2 - 2.6e-36 125.4 0.0 3.5e-36 124.9 0.0 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 CBK25202.2 - 3.4e-06 27.0 0.5 5.1e-06 26.5 0.5 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain HSP70 PF00012.20 CBK25203.2 - 2.1e-44 151.7 0.0 2.9e-44 151.3 0.0 1.1 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 CBK25203.2 - 1.5e-07 30.6 0.2 4.6e-07 29.0 0.0 1.9 2 1 0 2 2 2 1 MreB/Mbl protein StbA PF06406.11 CBK25203.2 - 0.024 13.9 0.0 0.08 12.2 0.0 1.8 1 1 0 1 1 1 0 StbA protein DDR PF08841.10 CBK25203.2 - 0.17 10.8 0.0 0.64 8.9 0.0 1.9 2 0 0 2 2 2 0 Diol dehydratase reactivase ATPase-like domain FancD2 PF14631.6 CBK25204.2 - 1.7e-22 78.8 1.8 2.5e-22 78.3 1.8 1.3 1 1 0 1 1 1 1 Fanconi anaemia protein FancD2 nuclease PAH PF02671.21 CBK25204.2 - 0.086 13.0 0.1 0.28 11.4 0.0 1.9 2 0 0 2 2 2 0 Paired amphipathic helix repeat FancD2 PF14631.6 CBK25205.2 - 6.8e-13 47.0 0.0 1.1e-11 43.0 0.0 1.9 1 1 0 1 1 1 1 Fanconi anaemia protein FancD2 nuclease Fumerase PF05681.14 CBK25206.2 - 1.6e-88 296.7 0.0 2.8e-88 295.9 0.0 1.4 1 0 0 1 1 1 1 Fumarate hydratase (Fumerase) Fumerase_C PF05683.12 CBK25206.2 - 1.2e-86 289.3 0.0 2.1e-86 288.5 0.0 1.5 1 0 0 1 1 1 1 Fumarase C-terminus BUD22 PF09073.10 CBK25206.2 - 0.18 11.1 31.4 0.26 10.6 31.4 1.1 1 0 0 1 1 1 0 BUD22 GREB1 PF15782.5 CBK25206.2 - 0.23 8.5 6.6 0.34 8.0 6.6 1.2 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer PI3K_1B_p101 PF10486.9 CBK25206.2 - 0.46 8.2 10.0 0.67 7.7 10.0 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Apt1 PF10351.9 CBK25206.2 - 1.1 8.1 13.2 1.5 7.5 13.2 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain OCC1 PF15506.6 CBK25206.2 - 7.8 6.7 7.3 9.4 6.4 3.0 2.8 3 0 0 3 3 3 0 OCC1 family UQ_con PF00179.26 CBK25207.2 - 7.7e-14 51.5 0.2 9.4e-14 51.3 0.2 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme PP2C PF00481.21 CBK25208.2 - 6.4e-21 75.1 0.0 8.4e-21 74.8 0.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C AAT PF03417.16 CBK25209.2 - 1.2e-24 87.2 0.0 1.6e-24 86.9 0.0 1.1 1 0 0 1 1 1 1 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase Myb_DNA-binding PF00249.31 CBK25210.2 - 4.2e-44 148.5 9.9 2.4e-18 66.0 1.2 3.3 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 CBK25210.2 - 2.2e-36 123.9 6.2 5.2e-16 58.6 0.3 3.3 2 1 1 3 3 3 3 Myb-like DNA-binding domain SLIDE PF09111.10 CBK25210.2 - 8.4e-07 29.0 0.0 0.13 12.3 0.0 3.4 1 1 2 3 3 3 3 SLIDE Collagen PF01391.18 CBK25210.2 - 1.2e-05 25.0 17.6 3.1e-05 23.6 17.6 1.7 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) Rap1_C PF11626.8 CBK25210.2 - 0.0001 22.3 2.9 0.34 11.0 0.0 3.4 1 1 1 2 2 2 2 TRF2-interacting telomeric protein/Rap1 - C terminal domain Myb_DNA-bind_7 PF15963.5 CBK25210.2 - 0.00021 21.1 0.4 0.001 18.9 0.0 2.2 3 0 0 3 3 3 1 Myb DNA-binding like Myb_DNA-bind_4 PF13837.6 CBK25210.2 - 0.018 15.4 9.3 0.14 12.5 0.9 3.4 3 1 0 3 3 3 0 Myb/SANT-like DNA-binding domain Ribosomal_S24e PF01282.19 CBK25211.2 - 1.2e-28 98.9 0.1 2.2e-28 98.0 0.0 1.5 1 1 0 1 1 1 1 Ribosomal protein S24e PSS PF03034.15 CBK25212.2 - 4.4e-103 344.8 21.2 5.5e-103 344.5 15.4 2.1 2 0 0 2 2 2 2 Phosphatidyl serine synthase Secretin_N_2 PF07655.13 CBK25212.2 - 0.0017 18.9 0.2 0.0029 18.1 0.2 1.3 1 0 0 1 1 1 1 Secretin N-terminal domain Spc7_C2 PF15577.6 CBK25213.2 - 0.13 12.4 0.0 3 8.0 0.0 2.4 2 0 0 2 2 2 0 Spc7_C2 DSPn PF14671.6 CBK25214.2 - 6.1e-39 133.7 3.7 1.4e-37 129.3 1.8 2.3 2 0 0 2 2 2 1 Dual specificity protein phosphatase, N-terminal half DSPc PF00782.20 CBK25214.2 - 3.4e-15 56.0 0.0 1.4e-14 54.1 0.0 1.9 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 CBK25214.2 - 5.3e-06 26.2 0.0 9.1e-06 25.4 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 CBK25214.2 - 0.0026 17.9 0.0 0.0065 16.6 0.0 1.6 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase3 PF13350.6 CBK25214.2 - 0.03 14.3 0.0 0.049 13.6 0.0 1.3 1 0 0 1 1 1 0 Tyrosine phosphatase family DUF2273 PF10031.9 CBK25214.2 - 0.047 13.7 0.9 0.081 13.0 0.9 1.4 1 0 0 1 1 1 0 Small integral membrane protein (DUF2273) PI3K_1B_p101 PF10486.9 CBK25214.2 - 4.1 5.1 7.2 6.9 4.3 7.2 1.3 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit KIX PF02172.16 CBK25215.2 - 0.099 12.9 0.1 0.13 12.5 0.1 1.2 1 0 0 1 1 1 0 KIX domain LRR_4 PF12799.7 CBK25216.2 - 1.5e-10 41.1 11.2 0.00047 20.5 0.9 3.6 2 1 2 4 4 4 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CBK25216.2 - 9.9e-10 38.0 7.5 8.4e-07 28.7 0.9 3.1 2 1 2 4 4 4 3 Leucine rich repeat LRR_1 PF00560.33 CBK25216.2 - 2.4e-05 24.2 9.1 2.2 9.1 0.2 5.1 4 0 0 4 4 4 3 Leucine Rich Repeat LRR_6 PF13516.6 CBK25216.2 - 10 6.5 11.5 16 5.9 0.1 4.3 5 0 0 5 5 5 0 Leucine Rich repeat ADP_ribosyl_GH PF03747.14 CBK25217.2 - 3.2e-14 53.4 0.0 3.6e-14 53.2 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylglycohydrolase CENP-T_C PF15511.6 CBK25218.2 - 2.7e-14 53.2 0.2 3.9e-14 52.7 0.2 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CBFD_NFYB_HMF PF00808.23 CBK25218.2 - 3.5e-05 24.0 0.0 5.2e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-S PF15630.6 CBK25218.2 - 0.0024 18.2 0.1 0.0046 17.3 0.1 1.4 1 0 0 1 1 1 1 CENP-S protein Fur_reg_FbpB PF13040.6 CBK25218.2 - 0.019 14.5 0.4 0.048 13.2 0.4 1.7 1 0 0 1 1 1 0 Fur-regulated basic protein B PHD PF00628.29 CBK25219.2 - 1.2e-08 34.7 4.6 1.9e-08 34.1 4.6 1.3 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.6 CBK25219.2 - 1.4e-05 25.3 0.5 2.3e-05 24.5 0.5 1.4 1 0 0 1 1 1 1 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.6 CBK25219.2 - 0.0016 18.6 0.6 0.0037 17.4 0.4 1.7 2 0 0 2 2 2 1 PHD-zinc-finger like domain PHD_2 PF13831.6 CBK25219.2 - 0.0019 17.7 0.1 0.0019 17.7 0.1 1.8 2 0 0 2 2 2 1 PHD-finger zf-rbx1 PF12678.7 CBK25219.2 - 0.0056 16.9 0.2 0.014 15.6 0.2 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RanBP PF00641.18 CBK25219.2 - 0.017 14.4 1.1 0.31 10.4 0.1 2.3 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others zf-ANAPC11 PF12861.7 CBK25219.2 - 0.12 12.5 1.0 0.22 11.6 1.0 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.6 CBK25219.2 - 1.4 9.3 7.9 0.99 9.8 2.8 2.6 2 1 0 2 2 2 0 Ring finger domain Zf_RING PF16744.5 CBK25219.2 - 2.6 8.2 5.8 11 6.3 5.8 2.1 1 1 0 1 1 1 0 KIAA1045 RING finger CHCH PF06747.13 CBK25221.2 - 0.0055 16.8 6.9 0.01 15.9 6.9 1.5 1 0 0 1 1 1 1 CHCH domain SesA PF17107.5 CBK25221.2 - 0.026 14.7 0.2 0.062 13.5 0.2 1.7 1 1 0 1 1 1 0 N-terminal domain on NACHT_NTPase and P-loop NTPases CX9C PF16860.5 CBK25221.2 - 0.13 12.3 4.8 0.22 11.6 4.8 1.3 1 0 0 1 1 1 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, SOG2 PF10428.9 CBK25221.2 - 0.26 10.4 24.7 0.31 10.2 24.7 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Presenilin PF01080.17 CBK25221.2 - 1.6 7.4 5.3 2 7.1 5.3 1.3 1 0 0 1 1 1 0 Presenilin SR-25 PF10500.9 CBK25221.2 - 1.6 8.3 23.2 2.4 7.7 23.2 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein TFIIA PF03153.13 CBK25221.2 - 5.1 7.0 15.7 7.3 6.5 15.7 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Ndc1_Nup PF09531.10 CBK25221.2 - 7.4 5.1 11.0 8 5.0 11.0 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup CYSTM PF12734.7 CBK25222.2 - 0.028 14.7 0.0 0.045 14.1 0.0 1.3 1 0 0 1 1 1 0 Cysteine-rich TM module stress tolerance Rsd_AlgQ PF04353.13 CBK25222.2 - 0.029 14.3 0.0 0.033 14.1 0.0 1.2 1 0 0 1 1 1 0 Regulator of RNA polymerase sigma(70) subunit, Rsd/AlgQ HSBP1 PF06825.12 CBK25222.2 - 0.041 13.7 0.3 0.063 13.1 0.3 1.3 1 0 0 1 1 1 0 Heat shock factor binding protein 1 DUF2157 PF09925.9 CBK25222.2 - 0.1 12.4 0.0 0.14 12.0 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2157) Fcf1 PF04900.12 CBK25223.2 - 1.2e-37 128.3 1.7 1.2e-37 128.3 1.7 1.8 2 0 0 2 2 2 1 Fcf1 PIN_9 PF18477.1 CBK25223.2 - 1.2e-12 48.1 0.5 2.5e-12 47.1 0.0 1.7 2 0 0 2 2 2 1 PIN like domain WHIM1 PF15612.6 CBK25223.2 - 0.027 14.0 0.0 0.054 13.1 0.0 1.5 1 0 0 1 1 1 0 WSTF, HB1, Itc1p, MBD9 motif 1 Cpn60_TCP1 PF00118.24 CBK25224.2 - 4.3e-164 546.8 0.3 4.9e-164 546.6 0.3 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Sec7 PF01369.20 CBK25225.2 - 7.9e-69 231.0 0.0 7.9e-69 231.0 0.0 3.2 5 0 0 5 5 5 1 Sec7 domain Sec7_N PF12783.7 CBK25225.2 - 4.1e-34 117.8 9.1 7.4e-34 116.9 3.9 3.8 4 0 0 4 4 4 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.10 CBK25225.2 - 3.5e-29 100.5 6.6 6.5e-26 90.0 0.0 4.4 5 0 0 5 5 5 2 Domain of unknown function (DUF1981) DCB PF16213.5 CBK25225.2 - 3.3e-06 26.9 0.0 3.3e-06 26.9 0.0 3.7 4 0 0 4 4 4 1 Dimerisation and cyclophilin-binding domain of Mon2 SDP_N PF12278.8 CBK25225.2 - 0.27 11.4 14.7 9.3 6.4 8.8 3.6 3 0 0 3 3 3 0 Sex determination protein N terminal DUF1635 PF07795.11 CBK25225.2 - 1.4 8.7 6.4 3.6 7.4 6.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1635) AF-4 PF05110.13 CBK25225.2 - 3.8 5.5 13.4 8.5 4.3 13.4 1.5 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Asparaginase_2 PF01112.18 CBK25226.2 - 6.4e-16 58.3 0.0 8.1e-16 57.9 0.0 1.2 1 0 0 1 1 1 1 Asparaginase CHAT PF12770.7 CBK25226.2 - 0.017 14.5 0.0 0.017 14.5 0.0 1.1 1 0 0 1 1 1 0 CHAT domain PP2C PF00481.21 CBK25227.2 - 4.7e-61 206.7 0.1 5.2e-61 206.5 0.1 1.0 1 0 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 CBK25227.2 - 0.00014 21.8 0.3 0.0013 18.7 0.3 2.0 1 1 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PAH PF02671.21 CBK25228.2 - 0.057 13.6 1.1 7.8 6.7 0.1 2.5 2 0 0 2 2 2 0 Paired amphipathic helix repeat SAM_1 PF00536.30 CBK25229.2 - 0.15 12.5 0.0 0.29 11.6 0.0 1.4 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) SBF_like PF13593.6 CBK25230.2 - 4e-32 111.8 23.3 4.3e-32 111.7 23.3 1.0 1 0 0 1 1 1 1 SBF-like CPA transporter family (DUF4137) SBF PF01758.16 CBK25230.2 - 1.4e-12 47.7 16.7 1.4e-12 47.7 16.7 1.7 1 1 0 1 1 1 1 Sodium Bile acid symporter family Pro_isomerase PF00160.21 CBK25231.2 - 1.6e-44 151.9 0.0 1.8e-44 151.8 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Fez1 PF06818.15 CBK25232.2 - 0.00073 20.0 16.0 0.0012 19.3 16.0 1.4 1 1 0 1 1 1 1 Fez1 DUF4200 PF13863.6 CBK25232.2 - 0.00095 19.6 2.6 0.00095 19.6 2.6 2.5 2 1 0 2 2 2 1 Domain of unknown function (DUF4200) Tmemb_cc2 PF10267.9 CBK25232.2 - 0.0053 16.0 7.4 0.0053 16.0 7.4 2.0 1 1 1 2 2 2 1 Predicted transmembrane and coiled-coil 2 protein TMF_DNA_bd PF12329.8 CBK25232.2 - 0.0082 16.1 1.5 0.0082 16.1 1.5 3.0 2 1 1 3 3 3 1 TATA element modulatory factor 1 DNA binding Phage_GP20 PF06810.11 CBK25232.2 - 0.013 15.3 7.2 0.14 11.9 0.6 2.3 2 1 0 2 2 2 0 Phage minor structural protein GP20 MitMem_reg PF13012.6 CBK25232.2 - 0.014 15.8 9.8 0.12 12.8 2.1 2.2 1 1 1 2 2 2 0 Maintenance of mitochondrial structure and function ADIP PF11559.8 CBK25232.2 - 0.018 15.1 4.9 0.018 15.1 4.9 2.1 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding ABC_tran_CTD PF16326.5 CBK25232.2 - 0.039 14.2 3.0 0.039 14.2 3.0 2.6 1 1 0 2 2 2 0 ABC transporter C-terminal domain DUF4618 PF15397.6 CBK25232.2 - 0.074 12.5 17.7 0.21 11.0 11.1 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4618) DUF641 PF04859.12 CBK25232.2 - 0.2 12.0 15.9 0.26 11.6 1.4 2.6 1 1 2 3 3 3 0 Plant protein of unknown function (DUF641) DASH_Dam1 PF08653.10 CBK25232.2 - 0.26 11.1 4.3 4 7.3 0.1 2.7 2 2 0 2 2 2 0 DASH complex subunit Dam1 Spc24 PF08286.11 CBK25232.2 - 0.32 11.2 19.5 0.25 11.6 4.7 2.7 1 1 2 3 3 3 0 Spc24 subunit of Ndc80 Swi5 PF07061.11 CBK25232.2 - 0.43 10.7 13.5 0.11 12.6 1.7 2.6 2 2 0 2 2 2 0 Swi5 APG6_N PF17675.1 CBK25232.2 - 0.5 10.9 22.5 3.4 8.2 7.4 2.3 1 1 1 2 2 2 0 Apg6 coiled-coil region DUF4298 PF14131.6 CBK25232.2 - 0.55 10.2 8.7 0.58 10.2 2.5 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF4298) DUF948 PF06103.11 CBK25232.2 - 0.58 10.5 2.5 2.8 8.3 0.1 2.4 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) DUF3450 PF11932.8 CBK25232.2 - 0.62 9.3 14.1 0.36 10.1 2.4 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) BORCS8 PF10167.9 CBK25232.2 - 0.73 9.8 8.6 0.53 10.3 0.6 2.1 2 0 0 2 2 2 0 BLOC-1-related complex sub-unit 8 FTA4 PF13093.6 CBK25232.2 - 0.79 9.6 12.8 2.1 8.2 4.6 2.1 1 1 1 2 2 2 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 ORF6C PF10552.9 CBK25232.2 - 0.81 9.8 10.4 2.5 8.2 1.7 2.6 2 1 0 2 2 2 0 ORF6C domain DUF724 PF05266.14 CBK25232.2 - 0.98 9.2 12.4 1.4 8.7 12.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF724) DUF812 PF05667.11 CBK25232.2 - 1.4 7.7 19.1 0.058 12.3 4.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF812) DUF5344 PF17279.2 CBK25232.2 - 1.6 9.4 11.2 5.1 7.8 0.6 2.7 2 2 0 2 2 2 0 Family of unknown function (DUF5344) Uso1_p115_C PF04871.13 CBK25232.2 - 1.7 9.0 18.7 1.2 9.5 7.0 2.5 2 1 0 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region THOC7 PF05615.13 CBK25232.2 - 1.8 8.9 14.4 0.36 11.1 4.0 2.2 2 0 0 2 2 2 0 Tho complex subunit 7 HIP1_clath_bdg PF16515.5 CBK25232.2 - 2.2 8.9 17.6 0.55 10.9 2.2 2.5 1 1 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Cluap1 PF10234.9 CBK25232.2 - 2.2 7.6 16.5 34 3.7 15.8 2.0 1 1 0 1 1 1 0 Clusterin-associated protein-1 DivIVA PF05103.13 CBK25232.2 - 2.2 8.3 14.5 2.2 8.4 4.7 2.4 1 1 1 2 2 2 0 DivIVA protein Prefoldin_2 PF01920.20 CBK25232.2 - 2.9 7.9 17.6 2.4 8.2 2.8 3.1 2 1 1 3 3 3 0 Prefoldin subunit OmpH PF03938.14 CBK25232.2 - 3.1 8.1 11.3 5.5 7.3 2.4 2.1 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) Fzo_mitofusin PF04799.13 CBK25232.2 - 3.7 7.1 9.3 6.4 6.3 1.3 2.2 2 0 0 2 2 2 0 fzo-like conserved region YlqD PF11068.8 CBK25232.2 - 4 7.8 12.9 1.5 9.2 2.4 2.2 1 1 1 2 2 2 0 YlqD protein Rho_Binding PF08912.11 CBK25232.2 - 4.3 8.2 21.1 8 7.4 6.7 2.6 2 1 1 3 3 3 0 Rho Binding Syntaxin-6_N PF09177.11 CBK25232.2 - 4.4 7.9 13.7 11 6.6 0.4 3.2 1 1 1 3 3 3 0 Syntaxin 6, N-terminal FlaC_arch PF05377.11 CBK25232.2 - 5.5 7.5 15.8 1.8 9.0 2.4 3.8 2 2 1 3 3 3 0 Flagella accessory protein C (FlaC) DUF745 PF05335.13 CBK25232.2 - 8.2 6.1 11.1 8.4 6.1 0.7 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF745) ERM PF00769.19 CBK25233.2 - 0.063 13.1 26.1 0.11 12.4 26.1 1.3 1 0 0 1 1 1 0 Ezrin/radixin/moesin family Med21 PF11221.8 CBK25233.2 - 0.11 12.7 24.6 0.067 13.4 16.8 2.7 1 1 1 2 2 2 0 Subunit 21 of Mediator complex DUF3106 PF11304.8 CBK25233.2 - 0.13 12.7 9.4 0.29 11.6 9.5 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3106) Fib_alpha PF08702.10 CBK25233.2 - 0.14 12.3 19.1 0.077 13.2 16.7 1.7 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family GBP_C PF02841.14 CBK25233.2 - 0.24 10.8 24.4 0.65 9.4 23.6 1.8 2 0 0 2 2 2 0 Guanylate-binding protein, C-terminal domain Baculo_PEP_C PF04513.12 CBK25233.2 - 0.27 11.3 11.1 5.5 7.0 2.7 3.0 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Fzo_mitofusin PF04799.13 CBK25233.2 - 0.27 10.8 18.3 1.9 8.0 6.6 2.4 1 1 1 2 2 2 0 fzo-like conserved region HalX PF08663.10 CBK25233.2 - 0.4 11.0 17.8 1.4 9.3 7.7 3.6 2 1 0 3 3 3 0 HalX domain DUF5082 PF16888.5 CBK25233.2 - 0.46 10.8 23.4 0.91 9.8 6.6 3.8 2 1 2 4 4 4 0 Domain of unknown function (DUF5082) ApoO PF09769.9 CBK25233.2 - 0.55 10.2 6.4 13 5.8 5.6 2.4 1 1 1 2 2 2 0 Apolipoprotein O Atg14 PF10186.9 CBK25233.2 - 0.95 8.5 20.9 2 7.4 20.9 1.6 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 V_ATPase_I PF01496.19 CBK25233.2 - 1 7.2 10.7 1.1 7.1 10.7 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF3450 PF11932.8 CBK25233.2 - 1.7 7.9 17.8 1.7 7.9 15.7 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) TSNAXIP1_N PF15739.5 CBK25233.2 - 2 8.8 21.1 6.1 7.3 10.6 2.6 2 1 1 3 3 3 0 Translin-associated factor X-interacting N-terminus ATG16 PF08614.11 CBK25233.2 - 2.6 8.2 24.7 4.8 7.4 22.0 2.3 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) Exonuc_VII_L PF02601.15 CBK25233.2 - 2.7 7.5 14.7 4 6.9 14.8 1.3 1 1 0 1 1 1 0 Exonuclease VII, large subunit UPF0242 PF06785.11 CBK25233.2 - 2.8 8.0 24.3 2.8 8.0 23.1 1.7 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus OEP PF02321.18 CBK25233.2 - 2.9 7.7 17.9 0.51 10.1 4.2 2.2 1 1 1 2 2 2 0 Outer membrane efflux protein Jnk-SapK_ap_N PF09744.9 CBK25233.2 - 3.3 7.9 31.0 7.7 6.7 16.2 2.6 2 1 1 3 3 3 0 JNK_SAPK-associated protein-1 Acetyltransf_3 PF13302.7 CBK25234.2 - 0.024 15.3 0.0 0.048 14.3 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 CBK25234.2 - 0.043 14.0 0.0 0.077 13.2 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Metallophos PF00149.28 CBK25235.2 - 9.8e-38 130.7 0.1 1.6e-37 130.0 0.1 1.3 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 CBK25235.2 - 0.028 14.6 0.0 0.04 14.1 0.0 1.2 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain DUF5378 PF17349.2 CBK25235.2 - 0.2 10.9 0.1 0.3 10.4 0.1 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5378) Pkinase PF00069.25 CBK25236.2 - 9e-45 153.1 0.0 1.2e-44 152.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBK25236.2 - 6.6e-18 64.9 0.0 1e-17 64.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Hist_deacetyl PF00850.19 CBK25237.2 - 2e-68 231.2 0.0 2.4e-68 230.9 0.0 1.0 1 0 0 1 1 1 1 Histone deacetylase domain PH_RBD PF12068.8 CBK25237.2 - 0.18 11.3 0.0 0.33 10.4 0.0 1.4 1 0 0 1 1 1 0 Rab-binding domain (RBD) Tfb4 PF03850.14 CBK25238.2 - 1.4e-06 28.0 0.0 2.9e-06 27.0 0.0 1.4 1 1 0 1 1 1 1 Transcription factor Tfb4 MFS_1 PF07690.16 CBK25239.2 - 9.1e-18 64.3 10.1 2e-14 53.3 3.8 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 CBK25239.2 - 4e-07 29.3 4.8 6.1e-06 25.4 0.7 2.1 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_4 PF06779.14 CBK25239.2 - 0.00027 20.4 0.6 0.00053 19.4 0.6 1.4 1 0 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB GTP_EFTU PF00009.27 CBK25240.2 - 9.9e-58 194.9 0.0 1.4e-57 194.4 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 CBK25240.2 - 2.5e-28 98.6 0.0 5e-28 97.6 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 CBK25240.2 - 8.3e-17 61.4 3.0 1.9e-16 60.2 3.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 CBK25240.2 - 4e-05 23.7 0.0 7.7e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase cobW PF02492.19 CBK25240.2 - 0.034 13.7 0.2 0.12 12.0 0.0 1.8 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain RsgA_GTPase PF03193.16 CBK25240.2 - 0.042 13.8 0.0 0.12 12.2 0.0 1.8 2 0 0 2 2 2 0 RsgA GTPase PduV-EutP PF10662.9 CBK25240.2 - 0.14 11.9 0.1 10 5.9 0.0 2.7 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation Oxidored_q6 PF01058.22 CBK25241.2 - 8.4e-23 80.6 0.0 1.4e-22 79.9 0.0 1.3 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit Secapin PF17521.2 CBK25241.2 - 0.07 12.9 0.8 0.18 11.6 0.0 2.1 2 0 0 2 2 2 0 Honey bee peptides HA2 PF04408.23 CBK25243.2 - 1.8e-21 76.4 0.0 4.3e-21 75.2 0.0 1.6 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 CBK25243.2 - 5.4e-14 52.3 0.0 1.1e-13 51.4 0.0 1.5 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 CBK25243.2 - 1.2e-13 51.3 0.0 7.1e-13 48.9 0.0 2.2 2 1 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 CBK25243.2 - 0.0002 21.2 0.2 0.002 17.9 0.1 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase MCR_D PF02505.14 CBK25243.2 - 0.1 12.4 0.0 0.23 11.3 0.0 1.5 1 0 0 1 1 1 0 Methyl-coenzyme M reductase operon protein D AAA_22 PF13401.6 CBK25244.2 - 0.00096 19.4 0.0 0.0013 19.1 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_23 PF13476.6 CBK25244.2 - 0.0015 19.1 0.9 0.0022 18.5 0.7 1.3 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.6 CBK25244.2 - 0.005 16.5 0.0 0.0076 16.0 0.0 1.3 1 0 0 1 1 1 1 P-loop containing region of AAA domain T2SSE PF00437.20 CBK25244.2 - 0.0057 15.8 0.0 0.0057 15.8 0.0 1.1 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_7 PF12775.7 CBK25244.2 - 0.0089 15.6 0.0 0.013 15.1 0.0 1.2 1 0 0 1 1 1 1 P-loop containing dynein motor region ATPase PF06745.13 CBK25244.2 - 0.011 15.0 0.1 0.016 14.5 0.1 1.3 1 0 0 1 1 1 0 KaiC ABC_tran PF00005.27 CBK25244.2 - 0.013 16.0 0.0 0.017 15.7 0.0 1.4 1 0 0 1 1 1 0 ABC transporter FtsK_SpoIIIE PF01580.18 CBK25244.2 - 0.02 14.2 0.1 0.031 13.6 0.1 1.3 1 1 0 1 1 1 0 FtsK/SpoIIIE family AAA_30 PF13604.6 CBK25244.2 - 0.026 14.2 0.1 0.035 13.8 0.1 1.2 1 0 0 1 1 1 0 AAA domain DEAD PF00270.29 CBK25244.2 - 0.032 14.0 0.0 0.038 13.7 0.0 1.2 1 0 0 1 1 1 0 DEAD/DEAH box helicase AAA_10 PF12846.7 CBK25244.2 - 0.05 12.5 0.0 0.061 12.2 0.0 1.1 1 0 0 1 1 1 0 AAA-like domain cobW PF02492.19 CBK25244.2 - 0.051 13.2 0.1 0.064 12.8 0.1 1.2 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_24 PF13479.6 CBK25244.2 - 0.052 13.3 0.0 0.15 11.8 0.0 1.7 2 0 0 2 2 2 0 AAA domain ResIII PF04851.15 CBK25244.2 - 0.063 13.3 0.0 0.071 13.1 0.0 1.3 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_19 PF13245.6 CBK25244.2 - 0.065 13.6 0.1 0.094 13.1 0.1 1.3 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 CBK25244.2 - 0.067 13.4 0.0 0.13 12.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 CBK25244.2 - 0.067 12.8 0.0 0.079 12.5 0.0 1.2 1 0 0 1 1 1 0 AAA domain FrhB_FdhB_N PF04422.13 CBK25244.2 - 0.091 12.9 0.0 0.13 12.4 0.0 1.4 1 0 0 1 1 1 0 Coenzyme F420 hydrogenase/dehydrogenase, beta subunit N-term PhoH PF02562.16 CBK25244.2 - 0.095 12.1 0.0 0.1 12.0 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein Zeta_toxin PF06414.12 CBK25244.2 - 0.11 11.7 0.3 0.53 9.5 0.0 2.0 1 1 1 2 2 2 0 Zeta toxin AAA_16 PF13191.6 CBK25244.2 - 0.14 12.6 0.0 0.14 12.5 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain Sigma54_activat PF00158.26 CBK25244.2 - 0.14 11.9 0.0 0.16 11.6 0.0 1.2 1 0 0 1 1 1 0 Sigma-54 interaction domain HSP20 PF00011.21 CBK25245.2 - 5.7e-27 93.9 2.3 6.8e-27 93.6 2.3 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 CBK25245.2 - 3e-13 49.1 0.0 5e-13 48.4 0.0 1.4 1 0 0 1 1 1 1 HSP20-like domain found in ArsA YqzE PF14038.6 CBK25245.2 - 0.72 9.9 2.6 0.99 9.5 0.3 2.4 3 0 0 3 3 3 0 YqzE-like protein Methyltr_RsmB-F PF01189.17 CBK25246.2 - 2.4e-19 69.8 0.0 5.3e-18 65.4 0.0 2.3 2 1 0 2 2 2 2 16S rRNA methyltransferase RsmB/F CPSase_L_D2 PF02786.17 CBK25247.2 - 2e-72 243.1 0.0 3.3e-72 242.4 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 CBK25247.2 - 6.6e-44 149.0 0.0 1.6e-43 147.7 0.0 1.7 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 CBK25247.2 - 1.9e-36 124.4 0.0 4.2e-36 123.3 0.0 1.6 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.22 CBK25247.2 - 4.5e-18 64.9 0.2 9.6e-18 63.8 0.2 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme PCC_BT PF18140.1 CBK25247.2 - 1.6e-10 41.4 0.1 1.4e-05 25.4 0.0 2.5 1 1 1 2 2 2 2 Propionyl-coenzyme A carboxylase BT domain Biotin_lipoyl_2 PF13533.6 CBK25247.2 - 2.9e-08 33.4 0.1 1.6e-07 31.1 0.0 2.1 1 1 1 2 2 2 1 Biotin-lipoyl like Dala_Dala_lig_C PF07478.13 CBK25247.2 - 8e-08 32.1 0.1 3.5e-07 30.0 0.0 2.0 1 1 1 2 2 2 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 CBK25247.2 - 2.5e-05 23.9 0.0 5.3e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain DUF2118 PF09891.9 CBK25247.2 - 0.0022 18.0 0.0 0.0054 16.7 0.0 1.6 1 0 0 1 1 1 1 Uncharacterized protein conserved in archaea (DUF2118) GCV_H PF01597.19 CBK25247.2 - 0.003 17.5 0.1 0.011 15.6 0.1 2.0 1 0 0 1 1 1 1 Glycine cleavage H-protein PTS_EIIA_1 PF00358.20 CBK25247.2 - 0.0036 17.1 0.0 0.01 15.6 0.0 1.8 1 0 0 1 1 1 1 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 Peptidase_M23 PF01551.22 CBK25247.2 - 0.026 14.7 0.1 0.29 11.4 0.0 2.3 2 0 0 2 2 2 0 Peptidase family M23 RnfC_N PF13375.6 CBK25247.2 - 0.05 13.6 0.0 0.12 12.3 0.0 1.6 1 0 0 1 1 1 0 RnfC Barrel sandwich hybrid domain PYNP_C PF07831.13 CBK25247.2 - 0.064 12.9 0.0 0.2 11.3 0.0 1.8 1 0 0 1 1 1 0 Pyrimidine nucleoside phosphorylase C-terminal domain HlyD_D23 PF16576.5 CBK25247.2 - 0.092 11.9 0.0 0.19 10.9 0.0 1.5 1 0 0 1 1 1 0 Barrel-sandwich domain of CusB or HlyD membrane-fusion HlyD_3 PF13437.6 CBK25247.2 - 0.12 13.1 0.2 0.49 11.1 0.1 2.2 2 1 0 2 2 2 0 HlyD family secretion protein DNA_pol_E_B PF04042.16 CBK25248.2 - 7.7e-16 58.1 0.0 9.8e-16 57.7 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B COPIIcoated_ERV PF07970.12 CBK25249.2 - 7.5e-18 65.2 0.5 8.8e-18 65.0 0.5 1.0 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter Shisa PF13908.6 CBK25250.2 - 0.00076 19.8 3.1 0.00076 19.8 3.1 1.5 1 1 0 1 1 1 1 Wnt and FGF inhibitory regulator WBP-1 PF11669.8 CBK25250.2 - 0.0069 17.0 0.0 0.014 16.0 0.0 1.5 1 0 0 1 1 1 1 WW domain-binding protein 1 EphA2_TM PF14575.6 CBK25250.2 - 0.042 14.7 0.1 0.074 13.9 0.1 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain SUR7 PF06687.12 CBK25250.2 - 0.086 12.5 8.3 0.12 12.0 8.3 1.2 1 0 0 1 1 1 0 SUR7/PalI family TMEM154 PF15102.6 CBK25250.2 - 0.094 12.6 1.7 0.16 11.8 1.1 1.5 1 1 1 2 2 2 0 TMEM154 protein family GRP PF07172.11 CBK25250.2 - 0.66 10.7 12.8 1.8 9.3 9.9 2.2 2 0 0 2 2 2 0 Glycine rich protein family TPT PF03151.16 CBK25251.2 - 2.2e-16 60.1 16.6 3.2e-16 59.6 16.6 1.2 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 CBK25251.2 - 0.017 15.3 26.1 0.51 10.5 5.8 2.9 2 2 0 2 2 2 0 EamA-like transporter family LUD_dom PF02589.15 CBK25251.2 - 0.071 12.8 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 LUD domain UPF0139 PF03669.13 CBK25251.2 - 3.5 7.5 6.9 7.2 6.5 0.2 3.3 3 1 0 3 3 3 0 Uncharacterised protein family (UPF0139) CPSase_L_D2 PF02786.17 CBK25252.2 - 2e-72 243.1 0.0 3.3e-72 242.4 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 CBK25252.2 - 6.6e-44 149.0 0.0 1.6e-43 147.7 0.0 1.7 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 CBK25252.2 - 1.9e-36 124.4 0.0 4.2e-36 123.3 0.0 1.6 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.22 CBK25252.2 - 4.5e-18 64.9 0.2 9.6e-18 63.8 0.2 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme PCC_BT PF18140.1 CBK25252.2 - 1.6e-10 41.4 0.1 1.4e-05 25.4 0.0 2.5 1 1 1 2 2 2 2 Propionyl-coenzyme A carboxylase BT domain Biotin_lipoyl_2 PF13533.6 CBK25252.2 - 2.9e-08 33.4 0.1 1.6e-07 31.1 0.0 2.1 1 1 1 2 2 2 1 Biotin-lipoyl like Dala_Dala_lig_C PF07478.13 CBK25252.2 - 8e-08 32.1 0.1 3.5e-07 30.0 0.0 2.0 1 1 1 2 2 2 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 CBK25252.2 - 2.5e-05 23.9 0.0 5.3e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain DUF2118 PF09891.9 CBK25252.2 - 0.0022 18.0 0.0 0.0054 16.7 0.0 1.6 1 0 0 1 1 1 1 Uncharacterized protein conserved in archaea (DUF2118) GCV_H PF01597.19 CBK25252.2 - 0.003 17.5 0.1 0.011 15.6 0.1 2.0 1 0 0 1 1 1 1 Glycine cleavage H-protein PTS_EIIA_1 PF00358.20 CBK25252.2 - 0.0036 17.1 0.0 0.01 15.6 0.0 1.8 1 0 0 1 1 1 1 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 Peptidase_M23 PF01551.22 CBK25252.2 - 0.026 14.7 0.1 0.29 11.4 0.0 2.3 2 0 0 2 2 2 0 Peptidase family M23 RnfC_N PF13375.6 CBK25252.2 - 0.05 13.6 0.0 0.12 12.3 0.0 1.6 1 0 0 1 1 1 0 RnfC Barrel sandwich hybrid domain PYNP_C PF07831.13 CBK25252.2 - 0.064 12.9 0.0 0.2 11.3 0.0 1.8 1 0 0 1 1 1 0 Pyrimidine nucleoside phosphorylase C-terminal domain HlyD_D23 PF16576.5 CBK25252.2 - 0.092 11.9 0.0 0.19 10.9 0.0 1.5 1 0 0 1 1 1 0 Barrel-sandwich domain of CusB or HlyD membrane-fusion HlyD_3 PF13437.6 CBK25252.2 - 0.12 13.1 0.2 0.49 11.1 0.1 2.2 2 1 0 2 2 2 0 HlyD family secretion protein HSP20 PF00011.21 CBK25253.2 - 5.7e-27 93.9 2.3 6.8e-27 93.6 2.3 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 CBK25253.2 - 3e-13 49.1 0.0 5e-13 48.4 0.0 1.4 1 0 0 1 1 1 1 HSP20-like domain found in ArsA YqzE PF14038.6 CBK25253.2 - 0.72 9.9 2.6 0.99 9.5 0.3 2.4 3 0 0 3 3 3 0 YqzE-like protein AAA_22 PF13401.6 CBK25254.2 - 0.00097 19.4 0.0 0.0014 19.0 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_23 PF13476.6 CBK25254.2 - 0.0015 19.1 0.9 0.0022 18.5 0.7 1.3 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.6 CBK25254.2 - 0.0051 16.5 0.0 0.0076 16.0 0.0 1.3 1 0 0 1 1 1 1 P-loop containing region of AAA domain T2SSE PF00437.20 CBK25254.2 - 0.0058 15.7 0.0 0.0058 15.7 0.0 1.1 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_7 PF12775.7 CBK25254.2 - 0.0088 15.6 0.0 0.013 15.0 0.0 1.2 1 0 0 1 1 1 1 P-loop containing dynein motor region ATPase PF06745.13 CBK25254.2 - 0.012 15.0 0.1 0.016 14.5 0.1 1.3 1 0 0 1 1 1 0 KaiC ABC_tran PF00005.27 CBK25254.2 - 0.013 16.1 0.0 0.016 15.7 0.0 1.4 1 0 0 1 1 1 0 ABC transporter FtsK_SpoIIIE PF01580.18 CBK25254.2 - 0.02 14.2 0.1 0.031 13.6 0.1 1.3 1 1 0 1 1 1 0 FtsK/SpoIIIE family AAA_30 PF13604.6 CBK25254.2 - 0.023 14.4 0.1 0.031 14.0 0.1 1.1 1 0 0 1 1 1 0 AAA domain DEAD PF00270.29 CBK25254.2 - 0.032 14.0 0.0 0.038 13.8 0.0 1.2 1 0 0 1 1 1 0 DEAD/DEAH box helicase AAA_10 PF12846.7 CBK25254.2 - 0.05 12.5 0.0 0.061 12.2 0.0 1.1 1 0 0 1 1 1 0 AAA-like domain cobW PF02492.19 CBK25254.2 - 0.051 13.2 0.1 0.064 12.8 0.1 1.2 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_24 PF13479.6 CBK25254.2 - 0.052 13.3 0.0 0.15 11.8 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.6 CBK25254.2 - 0.062 13.6 0.1 0.087 13.2 0.1 1.3 1 0 0 1 1 1 0 AAA domain ResIII PF04851.15 CBK25254.2 - 0.063 13.3 0.0 0.071 13.1 0.0 1.3 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_33 PF13671.6 CBK25254.2 - 0.068 13.3 0.0 0.13 12.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 CBK25254.2 - 0.071 12.7 0.0 0.083 12.4 0.0 1.2 1 0 0 1 1 1 0 AAA domain PhoH PF02562.16 CBK25254.2 - 0.076 12.5 0.2 0.099 12.1 0.2 1.4 1 1 0 1 1 1 0 PhoH-like protein FrhB_FdhB_N PF04422.13 CBK25254.2 - 0.091 12.9 0.0 0.13 12.4 0.0 1.4 1 0 0 1 1 1 0 Coenzyme F420 hydrogenase/dehydrogenase, beta subunit N-term Zeta_toxin PF06414.12 CBK25254.2 - 0.11 11.8 0.3 0.53 9.5 0.0 2.0 1 1 1 2 2 2 0 Zeta toxin SRP54 PF00448.22 CBK25254.2 - 0.13 11.8 0.1 0.15 11.6 0.1 1.2 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain Sigma54_activat PF00158.26 CBK25254.2 - 0.14 11.9 0.0 0.16 11.7 0.0 1.2 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_16 PF13191.6 CBK25254.2 - 0.14 12.5 0.0 0.14 12.5 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain HA2 PF04408.23 CBK25255.2 - 1.8e-21 76.4 0.0 4.3e-21 75.2 0.0 1.6 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 CBK25255.2 - 5.4e-14 52.3 0.0 1e-13 51.4 0.0 1.5 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 CBK25255.2 - 1.3e-13 51.2 0.0 7.1e-13 48.9 0.0 2.2 2 1 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 CBK25255.2 - 0.00013 21.8 0.3 0.0013 18.6 0.1 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase MCR_D PF02505.14 CBK25255.2 - 0.1 12.4 0.0 0.23 11.3 0.0 1.5 1 0 0 1 1 1 0 Methyl-coenzyme M reductase operon protein D LRR_4 PF12799.7 CBK25256.2 - 0.071 13.6 3.9 5.5 7.6 0.1 4.4 3 2 1 4 4 4 0 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CBK25256.2 - 0.082 12.7 0.7 2.2 8.1 0.0 3.1 3 1 1 4 4 4 0 Leucine rich repeat ACR_tran PF00873.19 CBK25257.2 - 0.12 10.0 0.0 0.2 9.3 0.0 1.2 1 0 0 1 1 1 0 AcrB/AcrD/AcrF family TK PF00265.18 CBK25258.2 - 0.14 12.1 0.1 0.25 11.2 0.1 1.4 1 0 0 1 1 1 0 Thymidine kinase Ribosomal_S19 PF00203.21 CBK25260.2 - 6.1e-34 115.8 0.2 7.4e-34 115.5 0.2 1.1 1 0 0 1 1 1 1 Ribosomal protein S19 SMC_N PF02463.19 CBK25261.2 - 6.2e-68 228.5 0.0 1e-67 227.8 0.0 1.4 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 CBK25261.2 - 9.6e-24 83.9 0.1 2.4e-23 82.6 0.1 1.8 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 CBK25261.2 - 1.8e-12 47.7 2.6 3.8e-05 23.6 0.1 2.8 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 CBK25261.2 - 2.7e-07 30.6 0.5 2.7e-07 30.6 0.5 3.3 3 1 0 3 3 3 1 AAA ATPase domain AAA_23 PF13476.6 CBK25261.2 - 3.6e-05 24.4 33.8 3.6e-05 24.4 33.8 6.0 2 2 0 2 2 1 1 AAA domain AAA_29 PF13555.6 CBK25261.2 - 6e-05 22.7 0.1 0.00014 21.5 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain GAS PF13851.6 CBK25261.2 - 0.00026 20.4 2.4 0.00026 20.4 2.4 6.9 4 2 4 8 8 5 1 Growth-arrest specific micro-tubule binding HIP1_clath_bdg PF16515.5 CBK25261.2 - 0.015 15.9 4.5 0.015 15.9 4.5 9.0 6 4 2 8 8 7 0 Clathrin-binding domain of Huntingtin-interacting protein 1 ABC_tran PF00005.27 CBK25261.2 - 0.04 14.4 0.0 0.04 14.4 0.0 5.2 3 2 1 4 4 4 0 ABC transporter TPR_8 PF13181.6 CBK25261.2 - 0.58 10.5 3.1 20 5.7 0.1 4.0 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF2293 PF10056.9 CBK25261.2 - 2.8 8.2 10.8 5.2 7.4 4.5 3.8 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2293) Baculo_PEP_C PF04513.12 CBK25261.2 - 4.8 7.2 12.8 3.5 7.7 0.2 3.6 4 0 0 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus Pkinase PF00069.25 CBK25263.2 - 2.7e-22 79.4 0.0 3.1e-22 79.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBK25263.2 - 2.6e-11 43.3 0.0 3.2e-11 43.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 CBK25263.2 - 0.00054 19.4 0.1 0.0008 18.8 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 CBK25263.2 - 0.04 13.2 0.0 0.55 9.5 0.0 2.0 1 1 0 1 1 1 0 Kinase-like FTA2 PF13095.6 CBK25263.2 - 0.086 12.5 0.3 1.5 8.4 0.1 2.1 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 TMEM72 PF16054.5 CBK25263.2 - 0.1 12.3 0.0 0.19 11.4 0.0 1.5 1 0 0 1 1 1 0 Transmembrane protein family 72 Ribosomal_L27e PF01777.18 CBK25264.2 - 1.9e-12 47.4 1.4 2.2e-12 47.1 1.4 1.1 1 0 0 1 1 1 1 Ribosomal L27e protein family CagY_M PF07337.11 CBK25264.2 - 0.033 13.8 0.5 0.053 13.1 0.5 1.4 1 0 0 1 1 1 0 DC-EC Repeat FAS_N PF17828.1 CBK25264.2 - 0.08 13.0 0.0 0.098 12.7 0.0 1.1 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta Aminotran_4 PF01063.19 CBK25266.2 - 8.1e-20 71.6 0.0 1.9e-19 70.4 0.0 1.6 1 1 0 1 1 1 1 Amino-transferase class IV Atypical_Card PF18461.1 CBK25266.2 - 0.021 15.0 0.1 0.16 12.2 0.0 2.2 2 0 0 2 2 2 0 Atypical caspase recruitment domain HK PF02110.15 CBK25268.2 - 1.8e-82 276.5 2.6 2e-82 276.3 2.6 1.0 1 0 0 1 1 1 1 Hydroxyethylthiazole kinase family Phos_pyr_kin PF08543.12 CBK25268.2 - 3.6e-07 29.8 0.4 4.5e-07 29.5 0.4 1.2 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase Carb_kinase PF01256.17 CBK25268.2 - 0.00015 21.3 0.3 0.00018 21.1 0.3 1.2 1 0 0 1 1 1 1 Carbohydrate kinase Ribosomal_L26 PF16906.5 CBK25269.2 - 6.2e-19 68.3 0.5 8.1e-19 67.9 0.5 1.2 1 0 0 1 1 1 1 Ribosomal proteins L26 eukaryotic, L24P archaeal KOW PF00467.29 CBK25269.2 - 9.3e-10 38.1 3.0 1.9e-09 37.1 3.0 1.7 1 1 0 1 1 1 1 KOW motif TPD PF14811.6 CBK25270.2 - 3.8e-11 43.0 0.0 7e-11 42.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function TPD sequence-motif MPP6 PF10175.9 CBK25272.2 - 2.6e-06 27.9 8.3 3.5e-06 27.5 8.3 1.2 1 0 0 1 1 1 1 M-phase phosphoprotein 6 RF-1 PF00472.20 CBK25272.2 - 0.0059 16.5 0.5 0.0059 16.5 0.5 1.9 2 0 0 2 2 2 1 RF-1 domain P2 PF07194.11 CBK25272.2 - 0.011 15.8 0.1 0.91 9.6 0.0 2.2 2 0 0 2 2 2 0 P2 response regulator binding domain DUF3991 PF13154.6 CBK25272.2 - 0.035 14.5 0.1 1.8 9.0 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3991) DUF2718 PF10918.8 CBK25272.2 - 0.036 14.6 0.0 0.066 13.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2718) DUF4524 PF15025.6 CBK25272.2 - 0.08 12.7 0.9 0.21 11.3 0.9 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4524) REPA_OB_2 PF16900.5 CBK25272.2 - 0.31 11.0 2.4 0.41 10.6 0.4 1.9 2 0 0 2 2 2 0 Replication protein A OB domain Agouti PF05039.12 CBK25272.2 - 0.37 11.5 4.9 0.31 11.8 0.6 2.1 1 1 1 2 2 2 0 Agouti protein Thioredoxin_8 PF13905.6 CBK25272.2 - 0.57 10.5 3.5 0.58 10.5 0.6 2.0 1 1 1 2 2 2 0 Thioredoxin-like ANAPC4_WD40 PF12894.7 CBK25273.2 - 0.00015 22.0 0.0 0.51 10.7 0.0 3.5 1 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Coatomer_WDAD PF04053.14 CBK25273.2 - 0.005 15.9 0.0 0.0062 15.6 0.0 1.1 1 0 0 1 1 1 1 Coatomer WD associated region PQQ_2 PF13360.6 CBK25273.2 - 0.018 14.6 0.0 0.027 14.0 0.0 1.3 1 0 0 1 1 1 0 PQQ-like domain PQQ PF01011.21 CBK25273.2 - 0.12 12.3 0.0 21 5.3 0.0 3.7 4 0 0 4 4 4 0 PQQ enzyme repeat WD40 PF00400.32 CBK25273.2 - 0.31 12.0 1.8 3.1 8.8 0.0 3.6 6 0 0 6 6 6 0 WD domain, G-beta repeat BRCT_2 PF16589.5 CBK25274.2 - 3.1e-09 37.1 0.1 4.9e-07 30.1 0.0 2.5 2 1 0 2 2 2 2 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 CBK25274.2 - 1.2e-06 28.8 0.2 0.024 15.0 0.1 2.6 2 1 0 2 2 2 2 BRCA1 C Terminus (BRCT) domain CybS PF05328.12 CBK25274.2 - 0.11 12.1 0.2 0.25 11.0 0.1 1.6 2 0 0 2 2 2 0 CybS, succinate dehydrogenase cytochrome B small subunit Glyco_hydro_38N PF01074.22 CBK25275.2 - 5.1e-83 278.8 9.4 7.6e-83 278.2 9.4 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.13 CBK25275.2 - 3.1e-24 86.3 0.0 6.6e-24 85.2 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.11 CBK25275.2 - 3.4e-19 68.8 0.1 1.1e-18 67.2 0.1 1.9 1 0 0 1 1 1 1 Alpha mannosidase middle domain Glyco_hydro38C2 PF17677.1 CBK25275.2 - 7.5e-06 26.0 0.0 2.9e-05 24.1 0.0 2.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal beta sandwich domain Glyco_hydro_57 PF03065.15 CBK25275.2 - 0.032 13.4 0.2 0.093 11.9 0.2 1.7 1 1 0 1 1 1 0 Glycosyl hydrolase family 57 AAA PF00004.29 CBK25276.2 - 1.2e-42 145.5 0.0 2.1e-42 144.7 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CBK25276.2 - 4.9e-13 48.7 0.1 1.4e-12 47.2 0.1 1.8 1 0 0 1 1 1 1 AAA+ lid domain Prot_ATP_ID_OB PF16450.5 CBK25276.2 - 2.2e-09 37.1 0.4 2.2e-09 37.1 0.4 2.4 3 0 0 3 3 2 1 Proteasomal ATPase OB C-terminal domain AAA_2 PF07724.14 CBK25276.2 - 8.6e-08 32.5 0.1 2.7e-07 30.9 0.0 1.8 2 0 0 2 2 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 CBK25276.2 - 2.5e-07 31.2 0.3 0.00015 22.2 0.1 2.6 2 1 1 3 3 2 1 AAA ATPase domain AAA_5 PF07728.14 CBK25276.2 - 3.3e-06 27.1 2.1 9.9e-06 25.6 0.2 2.7 3 1 0 3 3 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 CBK25276.2 - 4.4e-06 26.5 0.0 1.1e-05 25.2 0.0 1.6 2 0 0 2 2 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 CBK25276.2 - 1.2e-05 25.6 0.4 0.034 14.4 0.1 2.3 1 1 1 2 2 2 2 AAA domain AAA_7 PF12775.7 CBK25276.2 - 5.2e-05 22.8 0.0 0.00014 21.5 0.0 1.7 1 1 0 1 1 1 1 P-loop containing dynein motor region AAA_25 PF13481.6 CBK25276.2 - 0.00022 20.9 0.8 0.083 12.5 0.1 2.5 1 1 1 2 2 2 1 AAA domain AAA_18 PF13238.6 CBK25276.2 - 0.00054 20.5 2.0 0.0015 19.1 0.0 2.6 3 0 0 3 3 2 1 AAA domain AAA_24 PF13479.6 CBK25276.2 - 0.00069 19.4 0.0 0.0019 17.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain Prot_ATP_OB_N PF17758.1 CBK25276.2 - 0.00087 18.9 0.7 0.0026 17.4 0.1 2.0 2 0 0 2 2 2 1 Proteasomal ATPase OB N-terminal domain ATPase PF06745.13 CBK25276.2 - 0.0011 18.4 0.3 0.064 12.6 0.1 2.4 1 1 1 2 2 2 1 KaiC RNA_helicase PF00910.22 CBK25276.2 - 0.0013 19.1 0.0 0.0034 17.7 0.0 1.8 1 0 0 1 1 1 1 RNA helicase TIP49 PF06068.13 CBK25276.2 - 0.0015 17.8 0.3 0.0043 16.3 0.2 1.8 1 1 0 1 1 1 1 TIP49 P-loop domain Mg_chelatase PF01078.21 CBK25276.2 - 0.0027 17.1 0.0 0.0048 16.3 0.0 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 CBK25276.2 - 0.0037 17.0 0.0 0.0069 16.1 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein T2SSE PF00437.20 CBK25276.2 - 0.011 14.8 0.9 0.03 13.4 0.2 2.0 2 1 0 2 2 2 0 Type II/IV secretion system protein AAA_3 PF07726.11 CBK25276.2 - 0.013 15.4 0.0 0.034 14.0 0.0 1.8 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 CBK25276.2 - 0.013 15.7 0.0 0.027 14.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 CBK25276.2 - 0.014 15.4 0.0 0.031 14.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 CBK25276.2 - 0.014 15.3 0.0 0.7 9.8 0.0 2.3 1 1 1 2 2 2 0 NACHT domain Parvo_NS1 PF01057.17 CBK25276.2 - 0.015 14.4 0.1 0.036 13.2 0.1 1.6 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_26 PF13500.6 CBK25276.2 - 0.016 15.1 0.0 0.029 14.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 CBK25276.2 - 0.018 15.0 0.0 0.035 14.1 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE DUF815 PF05673.13 CBK25276.2 - 0.023 13.8 0.0 0.043 13.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_30 PF13604.6 CBK25276.2 - 0.025 14.3 0.1 0.071 12.8 0.1 1.7 1 1 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 CBK25276.2 - 0.029 14.1 0.1 0.098 12.4 0.0 1.9 2 1 0 2 2 1 0 Sigma-54 interaction domain Hydin_ADK PF17213.3 CBK25276.2 - 0.032 14.5 2.8 11 6.2 0.1 3.5 4 0 0 4 4 3 0 Hydin Adenylate kinase-like domain AAA_33 PF13671.6 CBK25276.2 - 0.039 14.1 0.0 0.11 12.7 0.0 1.9 1 0 0 1 1 1 0 AAA domain Sigma54_activ_2 PF14532.6 CBK25276.2 - 0.039 14.1 0.0 0.091 12.9 0.0 1.7 1 1 0 1 1 1 0 Sigma-54 interaction domain PhoH PF02562.16 CBK25276.2 - 0.071 12.6 0.2 0.16 11.4 0.2 1.5 1 0 0 1 1 1 0 PhoH-like protein EutN_CcmL PF03319.13 CBK25276.2 - 0.084 13.5 0.1 23 5.7 0.1 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation protein EutN/carboxysome AAA_19 PF13245.6 CBK25276.2 - 0.12 12.7 0.3 0.31 11.3 0.3 1.7 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.27 CBK25276.2 - 0.13 12.7 0.1 0.55 10.8 0.0 2.1 2 0 0 2 2 2 0 ABC transporter AAA_11 PF13086.6 CBK25276.2 - 0.18 11.6 0.1 0.18 11.6 0.1 2.3 3 1 0 3 3 3 0 AAA domain MFS_1 PF07690.16 CBK25277.2 - 8.3e-19 67.7 0.0 1e-18 67.4 0.0 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 CBK25277.2 - 5.9e-16 58.4 0.0 1e-15 57.6 0.0 1.4 1 1 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.13 CBK25277.2 - 0.00011 20.8 0.1 0.00013 20.6 0.1 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1_like PF12832.7 CBK25277.2 - 0.00034 19.6 0.5 0.05 12.4 0.3 2.9 2 1 0 2 2 2 1 MFS_1 like family MFS_2 PF13347.6 CBK25277.2 - 0.035 12.7 3.4 0.13 10.8 1.4 2.2 1 1 0 2 2 2 0 MFS/sugar transport protein zf-RNPHF PF08080.12 CBK25277.2 - 0.055 13.4 0.1 0.14 12.1 0.1 1.7 1 0 0 1 1 1 0 RNPHF zinc finger PIG-P PF08510.12 CBK25277.2 - 0.061 13.2 0.1 0.39 10.6 0.0 2.2 2 0 0 2 2 2 0 PIG-P SET PF00856.28 CBK25278.2 - 4.9e-23 82.3 0.4 1e-21 78.1 0.4 2.2 1 1 0 1 1 1 1 SET domain AWS PF17907.1 CBK25278.2 - 9.8e-16 57.5 10.0 9.8e-16 57.5 10.0 2.1 2 0 0 2 2 2 1 AWS domain TPR_2 PF07719.17 CBK25279.2 - 0.18 12.0 0.4 2.4 8.5 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat Amidohydro_1 PF01979.20 CBK25280.2 - 2.2e-14 53.6 0.0 2.6e-14 53.3 0.0 1.0 1 0 0 1 1 1 1 Amidohydrolase family ComA PF02679.15 CBK25280.2 - 0.099 12.1 0.0 0.15 11.5 0.0 1.2 1 0 0 1 1 1 0 (2R)-phospho-3-sulfolactate synthase (ComA) He_PIG PF05345.12 CBK25281.2 - 6e-05 23.2 0.1 0.00013 22.1 0.1 1.6 1 0 0 1 1 1 1 Putative Ig domain Protocadherin PF08374.11 CBK25281.2 - 0.0032 17.5 1.0 0.0045 17.0 1.0 1.2 1 0 0 1 1 1 1 Protocadherin DUF4834 PF16118.5 CBK25281.2 - 0.018 16.0 0.4 0.027 15.4 0.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) EphA2_TM PF14575.6 CBK25281.2 - 0.04 14.8 1.8 0.068 14.1 1.8 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain ASFV_J13L PF05568.11 CBK25281.2 - 0.057 13.2 1.0 0.089 12.5 1.0 1.3 1 0 0 1 1 1 0 African swine fever virus J13L protein OSTbeta PF15048.6 CBK25281.2 - 0.062 13.4 1.1 0.1 12.7 1.1 1.3 1 0 0 1 1 1 0 Organic solute transporter subunit beta protein HemY_N PF07219.13 CBK25281.2 - 0.12 12.6 0.6 0.2 11.9 0.6 1.3 1 0 0 1 1 1 0 HemY protein N-terminus Amnionless PF14828.6 CBK25281.2 - 0.13 11.0 0.0 0.17 10.7 0.0 1.1 1 0 0 1 1 1 0 Amnionless TMEM132D_C PF15706.5 CBK25281.2 - 0.17 11.7 0.1 0.3 10.9 0.1 1.4 1 0 0 1 1 1 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term DUF4381 PF14316.6 CBK25281.2 - 0.26 11.5 0.0 0.38 11.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) Cadherin_C_2 PF16492.5 CBK25281.2 - 0.27 12.0 1.5 0.63 10.8 1.5 1.6 1 0 0 1 1 1 0 Cadherin cytoplasmic C-terminal OAD_gamma PF04277.13 CBK25281.2 - 2.1 9.0 7.4 6.1 7.5 7.4 1.7 1 1 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain SET PF00856.28 CBK25282.2 - 7.8e-08 32.9 0.1 2.2e-07 31.4 0.1 1.7 1 1 0 1 1 1 1 SET domain Yip1 PF04893.17 CBK25283.2 - 8.8e-07 28.8 7.8 3.6e-06 26.8 7.8 1.8 1 1 0 1 1 1 1 Yip1 domain GCV_T PF01571.21 CBK25284.2 - 1.7e-77 260.3 0.0 2.2e-77 259.9 0.0 1.1 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.11 CBK25284.2 - 2.4e-24 85.0 0.2 6.8e-24 83.6 0.2 1.7 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain SoxG PF04268.12 CBK25284.2 - 0.19 11.9 0.0 0.35 11.0 0.0 1.4 1 0 0 1 1 1 0 Sarcosine oxidase, gamma subunit family FtsJ PF01728.19 CBK25285.2 - 7.2e-56 189.1 0.3 1.9e-55 187.7 0.1 1.8 2 0 0 2 2 2 1 FtsJ-like methyltransferase DUF3381 PF11861.8 CBK25285.2 - 1.3e-38 132.4 12.1 1.3e-38 132.4 12.1 5.2 3 1 0 3 3 3 1 Domain of unknown function (DUF3381) Spb1_C PF07780.12 CBK25285.2 - 3e-37 128.3 22.3 3e-37 128.3 22.3 4.5 3 3 0 3 3 3 1 Spb1 C-terminal domain Methyltr_RsmB-F PF01189.17 CBK25285.2 - 0.047 13.3 0.0 0.19 11.4 0.0 2.0 1 0 0 1 1 1 0 16S rRNA methyltransferase RsmB/F Methyltrans_Mon PF14314.6 CBK25285.2 - 0.16 10.0 0.4 0.34 8.9 0.0 1.6 2 0 0 2 2 2 0 Virus-capping methyltransferase Collagen PF01391.18 CBK25285.2 - 1.8 8.4 9.2 0.54 10.1 2.1 2.3 2 0 0 2 2 2 0 Collagen triple helix repeat (20 copies) Ribosomal_L40e PF01020.17 CBK25286.2 - 3e-29 100.7 13.8 4.2e-29 100.2 13.8 1.2 1 0 0 1 1 1 1 Ribosomal L40e family ubiquitin PF00240.23 CBK25286.2 - 1.8e-21 75.6 0.3 2.6e-21 75.1 0.3 1.2 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 CBK25286.2 - 1.5e-10 40.7 0.2 2.4e-10 40.1 0.2 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Rad60-SLD_2 PF13881.6 CBK25286.2 - 0.00014 21.9 0.1 0.00027 21.0 0.1 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 CBK25286.2 - 0.0047 17.5 0.0 0.0047 17.5 0.0 1.2 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain CK_II_beta PF01214.18 CBK25287.2 - 6.2e-71 238.0 1.1 8.8e-71 237.5 1.1 1.2 1 0 0 1 1 1 1 Casein kinase II regulatory subunit CH PF00307.31 CBK25288.2 - 3.4e-05 24.0 0.3 8.4e-05 22.7 0.1 1.7 2 0 0 2 2 2 1 Calponin homology (CH) domain Golgin_A5 PF09787.9 CBK25288.2 - 0.0032 17.0 0.8 0.0072 15.8 0.7 1.5 2 0 0 2 2 2 1 Golgin subfamily A member 5 CC2-LZ PF16516.5 CBK25288.2 - 0.0053 17.1 0.5 0.014 15.7 0.5 1.7 1 0 0 1 1 1 1 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator CAMSAP_CH PF11971.8 CBK25288.2 - 0.013 15.3 0.0 0.028 14.3 0.0 1.5 1 0 0 1 1 1 0 CAMSAP CH domain HMMR_N PF15905.5 CBK25288.2 - 0.024 14.1 2.0 0.048 13.1 1.7 1.6 1 1 1 2 2 2 0 Hyaluronan mediated motility receptor N-terminal Rx_N PF18052.1 CBK25288.2 - 0.036 14.3 1.2 0.089 13.1 1.2 1.8 1 0 0 1 1 1 0 Rx N-terminal domain ATG16 PF08614.11 CBK25288.2 - 0.054 13.7 4.4 0.044 14.0 3.2 1.5 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) TMF_DNA_bd PF12329.8 CBK25288.2 - 0.056 13.4 0.9 0.056 13.4 0.9 2.0 2 1 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Goodbye PF17109.5 CBK25288.2 - 0.15 12.5 0.4 26 5.3 0.1 2.3 2 0 0 2 2 2 0 fungal STAND N-terminal Goodbye domain tRNA_edit PF04073.15 CBK25289.2 - 0.0017 18.4 0.0 0.0021 18.1 0.0 1.1 1 0 0 1 1 1 1 Aminoacyl-tRNA editing domain LRR_5 PF13306.6 CBK25291.2 - 0.0057 16.6 2.7 0.0089 16.0 2.7 1.2 1 0 0 1 1 1 1 BspA type Leucine rich repeat region (6 copies) hSac2 PF12456.8 CBK25291.2 - 0.013 15.2 0.3 1.8 8.3 0.0 3.1 1 1 2 3 3 3 0 Inositol phosphatase LRR_8 PF13855.6 CBK25291.2 - 0.12 12.2 0.3 0.93 9.3 0.1 2.6 3 0 0 3 3 3 0 Leucine rich repeat AhpC-TSA PF00578.21 CBK25292.2 - 8e-36 122.7 0.0 1.1e-35 122.3 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 CBK25292.2 - 1.2e-11 44.6 0.0 1.5e-11 44.2 0.0 1.1 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.9 CBK25292.2 - 1.8e-11 43.7 0.0 3.8e-11 42.6 0.0 1.5 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin WD40 PF00400.32 CBK25293.2 - 5.5e-17 61.8 4.1 1e-06 29.3 0.3 3.1 3 0 0 3 3 3 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBK25293.2 - 2.5e-06 27.7 0.1 0.048 14.0 0.0 3.0 1 1 2 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain IKI3 PF04762.12 CBK25293.2 - 0.00067 17.8 0.3 0.00074 17.7 0.3 1.0 1 0 0 1 1 1 1 IKI3 family Ge1_WD40 PF16529.5 CBK25293.2 - 0.014 14.4 0.0 0.98 8.3 0.0 2.2 1 1 1 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Nbas_N PF15492.6 CBK25293.2 - 0.014 14.8 0.2 7.4 5.8 0.0 2.9 2 1 1 3 3 3 0 Neuroblastoma-amplified sequence, N terminal PD40 PF07676.12 CBK25293.2 - 0.016 15.1 0.6 8.7 6.4 0.0 3.2 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat Glyco_hydro_31 PF01055.26 CBK25294.2 - 1.2e-123 413.6 3.3 1.7e-123 413.1 3.3 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.6 CBK25294.2 - 1.2e-17 64.0 0.2 8.5e-17 61.2 0.0 2.5 3 0 0 3 3 3 1 Galactose mutarotase-like Ist1 PF03398.14 CBK25296.2 - 4.7e-08 33.1 5.2 8.4e-08 32.3 5.2 1.4 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway DUF2201_N PF13203.6 CBK25296.2 - 0.012 15.2 1.0 0.012 15.2 1.0 2.4 1 1 1 2 2 2 0 Putative metallopeptidase domain UPF0051 PF01458.17 CBK25297.2 - 5.4e-33 114.5 0.0 7.3e-33 114.1 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized protein family (UPF0051) DUF4675 PF15720.5 CBK25297.2 - 0.16 11.7 0.7 0.31 10.8 0.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4675) ABC_tran PF00005.27 CBK25298.2 - 1.2e-21 77.7 0.0 1.7e-21 77.1 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 CBK25298.2 - 4.8e-09 36.5 3.4 3.2e-05 23.9 0.3 2.5 2 1 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 CBK25298.2 - 0.0001 21.8 0.1 0.0004 19.9 0.1 1.8 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 CBK25298.2 - 0.00013 21.6 0.3 0.00026 20.6 0.3 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 CBK25298.2 - 0.0012 18.8 0.1 0.0018 18.2 0.1 1.3 1 0 0 1 1 1 1 RsgA GTPase AAA_23 PF13476.6 CBK25298.2 - 0.0032 18.0 0.1 0.0041 17.7 0.1 1.4 1 0 0 1 1 1 1 AAA domain AAA_15 PF13175.6 CBK25298.2 - 0.005 16.6 0.0 0.052 13.3 0.0 1.9 1 1 1 2 2 2 1 AAA ATPase domain AAA_27 PF13514.6 CBK25298.2 - 0.016 14.8 0.0 0.024 14.2 0.0 1.2 1 0 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 CBK25298.2 - 0.034 14.1 0.1 0.057 13.3 0.1 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_25 PF13481.6 CBK25298.2 - 0.037 13.6 0.0 0.056 13.0 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 CBK25298.2 - 0.074 13.2 0.0 0.13 12.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 CBK25298.2 - 0.093 13.2 0.0 0.2 12.1 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Herpes_Helicase PF02689.14 CBK25298.2 - 0.11 10.3 0.1 0.15 10.0 0.1 1.1 1 0 0 1 1 1 0 Helicase AAA_22 PF13401.6 CBK25298.2 - 0.15 12.3 0.0 0.36 11.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 CBK25298.2 - 0.16 11.5 0.1 0.26 10.8 0.1 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region SNARE PF05739.19 CBK25299.2 - 6.6e-14 51.6 0.1 1.2e-13 50.8 0.1 1.5 1 0 0 1 1 1 1 SNARE domain Syntaxin PF00804.25 CBK25299.2 - 3.9e-05 23.4 2.8 3.9e-05 23.4 2.8 1.4 2 0 0 2 2 2 1 Syntaxin DUF2570 PF10828.8 CBK25299.2 - 0.0002 21.1 3.2 0.00028 20.7 3.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2570) CDT1_C PF16679.5 CBK25299.2 - 0.0076 16.7 0.9 0.0098 16.3 0.9 1.2 1 0 0 1 1 1 1 DNA replication factor Cdt1 C-terminal domain Tweety PF04906.13 CBK25299.2 - 0.025 13.2 0.2 0.029 13.0 0.2 1.0 1 0 0 1 1 1 0 Tweety H-kinase_dim PF02895.14 CBK25299.2 - 0.042 14.2 3.8 3.2 8.2 0.0 2.3 1 1 1 2 2 2 0 Signal transducing histidine kinase, homodimeric domain Caps_synth_GfcC PF06251.11 CBK25299.2 - 0.058 13.0 2.7 0.077 12.6 2.4 1.2 1 1 0 1 1 1 0 Capsule biosynthesis GfcC Filament PF00038.21 CBK25299.2 - 0.064 12.8 5.7 0.075 12.6 5.7 1.1 1 0 0 1 1 1 0 Intermediate filament protein SAS4 PF15460.6 CBK25299.2 - 0.092 12.8 1.5 0.15 12.2 1.5 1.4 1 0 0 1 1 1 0 Something about silencing, SAS, complex subunit 4 Abi_C PF14355.6 CBK25299.2 - 0.17 12.0 0.5 9 6.5 0.2 2.3 1 1 1 2 2 2 0 Abortive infection C-terminus SlyX PF04102.12 CBK25299.2 - 1 10.0 6.4 1.3 9.7 3.8 2.2 1 1 1 2 2 2 0 SlyX Laminin_EGF PF00053.24 CBK25301.2 - 1.6e-05 25.0 87.6 0.31 11.2 9.0 7.1 3 1 3 6 6 6 4 Laminin EGF domain EGF_2 PF07974.13 CBK25301.2 - 0.00038 20.8 101.0 0.00085 19.6 11.3 8.0 4 2 3 7 7 7 4 EGF-like domain hEGF PF12661.7 CBK25301.2 - 0.002 18.7 23.6 0.0066 17.0 7.3 7.5 7 1 0 7 7 7 3 Human growth factor-like EGF DUF4309 PF14172.6 CBK25301.2 - 0.093 12.7 0.2 0.14 12.1 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4309) ODV-E18 PF10717.9 CBK25301.2 - 0.31 11.0 1.4 0.7 9.8 1.4 1.6 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 Insulin_TMD PF17870.1 CBK25301.2 - 2.2 8.4 5.3 0.28 11.3 1.1 1.7 2 0 0 2 2 2 0 Insulin receptor trans-membrane segment Pkinase PF00069.25 CBK25302.2 - 2e-19 70.0 0.0 4e-19 69.0 0.0 1.4 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBK25302.2 - 3.5e-11 42.9 0.0 3.9e-11 42.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CBK25302.2 - 0.0015 17.9 0.0 0.0024 17.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 CBK25302.2 - 0.014 14.8 0.0 0.019 14.3 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CBK25302.2 - 0.019 14.9 0.0 0.028 14.3 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family CLASP_N PF12348.8 CBK25303.2 - 3.4e-07 30.1 0.2 3.8e-07 29.9 0.2 1.1 1 0 0 1 1 1 1 CLASP N terminal DLIC PF05783.11 CBK25304.2 - 0.13 11.1 6.3 0.17 10.7 6.3 1.1 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) Pectate_lyase_3 PF12708.7 CBK25305.2 - 6.6e-07 29.4 3.4 6.6e-07 29.4 3.4 2.0 1 1 1 2 2 2 1 Pectate lyase superfamily protein Aminotran_1_2 PF00155.21 CBK25308.2 - 7.2e-39 134.0 0.0 9.3e-39 133.6 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Ribosomal_S4e PF00900.20 CBK25309.2 - 2.1e-32 110.8 0.7 6.5e-32 109.3 0.7 1.8 1 0 0 1 1 1 1 Ribosomal family S4e 40S_S4_C PF16121.5 CBK25309.2 - 5e-26 90.1 0.0 8.9e-26 89.3 0.0 1.4 1 0 0 1 1 1 1 40S ribosomal protein S4 C-terminus KOW PF00467.29 CBK25309.2 - 0.00011 22.1 2.1 0.00011 22.1 2.1 3.0 4 0 0 4 4 4 1 KOW motif S4 PF01479.25 CBK25309.2 - 0.0044 16.7 0.2 0.01 15.5 0.0 1.8 2 0 0 2 2 2 1 S4 domain DUF4056 PF13265.6 CBK25309.2 - 0.23 10.8 0.4 0.39 10.0 0.3 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF4056) CLP1_P PF16575.5 CBK25310.2 - 1.1e-41 142.7 0.0 1.4e-41 142.3 0.0 1.2 1 0 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop FtsK_SpoIIIE PF01580.18 CBK25310.2 - 0.00039 19.9 0.0 0.00063 19.2 0.0 1.2 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_22 PF13401.6 CBK25310.2 - 0.063 13.5 0.0 1.4 9.2 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.6 CBK25310.2 - 0.15 12.1 0.0 0.32 11.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain Hist_deacetyl PF00850.19 CBK25310.2 - 0.19 11.2 0.0 0.29 10.6 0.0 1.2 1 0 0 1 1 1 0 Histone deacetylase domain Sec1 PF00995.23 CBK25311.2 - 3.9e-46 158.5 0.1 4.7e-46 158.2 0.1 1.0 1 0 0 1 1 1 1 Sec1 family NRN1 PF15056.6 CBK25311.2 - 0.058 13.5 0.0 2.2 8.4 0.0 2.2 2 0 0 2 2 2 0 Neuritin protein family Sec1 PF00995.23 CBK25312.2 - 6.2e-09 35.6 0.0 6.3e-09 35.6 0.0 1.0 1 0 0 1 1 1 1 Sec1 family AhpC-TSA PF00578.21 CBK25313.2 - 8e-36 122.7 0.0 1.1e-35 122.3 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 CBK25313.2 - 1.2e-11 44.6 0.0 1.5e-11 44.2 0.0 1.1 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.9 CBK25313.2 - 1.8e-11 43.7 0.0 3.8e-11 42.6 0.0 1.5 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin Collagen PF01391.18 CBK25315.2 - 0.14 11.9 4.1 0.22 11.3 4.1 1.2 1 0 0 1 1 1 0 Collagen triple helix repeat (20 copies) Lipase_3 PF01764.25 CBK25317.2 - 6.7e-10 39.0 0.1 2.3e-09 37.3 0.0 2.0 2 0 0 2 2 2 1 Lipase (class 3) PPR PF01535.20 CBK25317.2 - 5.7e-05 23.1 0.5 5.6 7.5 0.0 4.5 3 0 0 3 3 3 2 PPR repeat PPR_2 PF13041.6 CBK25317.2 - 0.021 15.0 1.8 9.7 6.5 0.0 4.7 5 0 0 5 5 5 0 PPR repeat family PGAP1 PF07819.13 CBK25317.2 - 0.033 13.9 0.1 0.1 12.3 0.0 1.8 2 0 0 2 2 2 0 PGAP1-like protein Viral_P18 PF04521.13 CBK25317.2 - 0.12 12.2 0.0 0.28 11.0 0.0 1.7 1 0 0 1 1 1 0 ssRNA positive strand viral 18kD cysteine rich protein Abhydrolase_6 PF12697.7 CBK25317.2 - 0.19 12.3 0.0 0.3 11.6 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Fer2 PF00111.27 CBK25318.2 - 2.3e-13 49.9 2.7 3.1e-13 49.5 2.7 1.2 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer2_4 PF13510.6 CBK25318.2 - 0.026 14.5 1.3 0.08 13.0 1.3 2.0 1 1 0 1 1 1 0 2Fe-2S iron-sulfur cluster binding domain UNC-93 PF05978.16 CBK25319.2 - 6.2e-10 39.0 8.6 1.3e-09 37.9 7.9 1.9 1 1 1 2 2 2 1 Ion channel regulatory protein UNC-93 Paf1 PF03985.13 CBK25320.2 - 3.2e-13 49.5 0.0 7.1e-13 48.3 0.0 1.5 1 1 0 1 1 1 1 Paf1 Cpn60_TCP1 PF00118.24 CBK25321.2 - 2.5e-98 329.8 16.7 3.4e-98 329.4 16.7 1.2 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Trypan_PARP PF05887.11 CBK25322.2 - 0.0002 21.3 33.6 0.0002 21.3 33.6 4.6 1 1 2 4 4 4 1 Procyclic acidic repetitive protein (PARP) PP-binding PF00550.25 CBK25323.2 - 1.4e-10 41.3 0.2 1.5e-10 41.3 0.2 1.0 1 0 0 1 1 1 1 Phosphopantetheine attachment site PP-binding_2 PF14573.6 CBK25323.2 - 0.0017 18.5 0.4 0.002 18.3 0.4 1.1 1 0 0 1 1 1 1 Acyl-carrier TAF PF02969.17 CBK25323.2 - 0.039 14.1 0.1 0.052 13.7 0.1 1.2 1 0 0 1 1 1 0 TATA box binding protein associated factor (TAF) Glu-tRNAGln PF02686.15 CBK25323.2 - 0.084 13.2 0.5 0.1 12.9 0.5 1.2 1 0 0 1 1 1 0 Glu-tRNAGln amidotransferase C subunit SMC_N PF02463.19 CBK25324.2 - 6.2e-68 228.5 0.0 1e-67 227.8 0.0 1.4 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 CBK25324.2 - 9.7e-24 83.9 0.1 2.4e-23 82.6 0.1 1.8 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 CBK25324.2 - 1.8e-12 47.7 2.6 3.8e-05 23.6 0.1 2.8 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 CBK25324.2 - 1.1e-06 28.7 2.3 1.1e-06 28.7 2.3 3.3 3 1 0 3 3 3 1 AAA ATPase domain AAA_23 PF13476.6 CBK25324.2 - 2.2e-05 25.0 33.1 2.2e-05 25.0 33.1 6.0 2 2 0 2 2 2 1 AAA domain AAA_29 PF13555.6 CBK25324.2 - 5.9e-05 22.7 0.1 0.00014 21.5 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain GAS PF13851.6 CBK25324.2 - 0.00019 20.9 1.9 0.00019 20.9 1.9 6.9 4 2 5 9 9 9 1 Growth-arrest specific micro-tubule binding ABC_tran PF00005.27 CBK25324.2 - 0.12 12.9 22.9 0.3 11.6 3.0 5.2 3 2 0 3 3 3 0 ABC transporter TPR_8 PF13181.6 CBK25324.2 - 0.58 10.5 3.1 20 5.7 0.1 4.0 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF2293 PF10056.9 CBK25324.2 - 2.5 8.4 10.8 5.2 7.4 4.5 3.9 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2293) Mito_fiss_reg PF05308.11 CBK25325.2 - 0.099 12.7 0.7 0.12 12.5 0.7 1.1 1 0 0 1 1 1 0 Mitochondrial fission regulator CAP_N PF01213.19 CBK25325.2 - 7.6 5.9 8.4 9.7 5.6 8.4 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal DNA_pol_B_2 PF03175.13 CBK25326.2 - 1.6e-16 60.3 12.9 5.5e-14 51.9 8.8 2.3 2 0 0 2 2 2 2 DNA polymerase type B, organellar and viral Ribosomal_L3 PF00297.22 CBK25327.2 - 4.9e-175 581.9 9.5 5.6e-175 581.7 9.5 1.0 1 0 0 1 1 1 1 Ribosomal protein L3 La PF05383.17 CBK25328.2 - 1.1e-20 73.4 0.3 2.5e-20 72.3 0.3 1.6 1 0 0 1 1 1 1 La domain RRM_1 PF00076.22 CBK25328.2 - 9.5e-05 22.1 0.1 0.00033 20.4 0.0 2.1 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FAM199X PF15814.5 CBK25328.2 - 0.79 8.7 7.8 1.9 7.5 7.8 1.6 1 0 0 1 1 1 0 Protein family FAM199X CDC27 PF09507.10 CBK25328.2 - 1.3 8.3 21.5 2.5 7.4 21.5 1.5 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 FSA_C PF10479.9 CBK25328.2 - 6.3 4.8 10.3 8.8 4.3 10.3 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus Ldh_1_N PF00056.23 CBK25329.2 - 8e-44 149.2 0.0 1.1e-43 148.7 0.0 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.18 CBK25329.2 - 6.7e-42 143.3 0.0 9.8e-42 142.7 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain 3Beta_HSD PF01073.19 CBK25329.2 - 0.0024 16.9 0.0 0.0032 16.5 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family TPR_14 PF13428.6 CBK25330.2 - 1.5e-09 37.9 13.9 0.014 16.1 0.0 6.2 6 2 2 8 8 8 3 Tetratricopeptide repeat TPR_19 PF14559.6 CBK25330.2 - 6.9e-08 32.9 13.1 0.73 10.4 0.1 5.8 5 1 1 6 6 6 4 Tetratricopeptide repeat TPR_16 PF13432.6 CBK25330.2 - 0.00039 21.0 4.3 1.4 9.7 2.3 4.0 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_15 PF13429.6 CBK25330.2 - 0.00072 18.9 10.2 0.0042 16.3 0.1 2.9 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 CBK25330.2 - 0.0026 17.7 13.5 2.8 8.3 0.0 6.4 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_12 PF13424.6 CBK25330.2 - 0.0097 16.2 8.3 2 8.8 0.0 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 CBK25330.2 - 0.02 15.1 11.3 0.21 11.9 0.0 5.9 7 0 0 7 7 7 0 Tetratricopeptide repeat Suf PF05843.14 CBK25330.2 - 0.12 12.3 0.0 0.12 12.3 0.0 2.1 2 1 0 2 2 2 0 Suppressor of forked protein (Suf) Coatomer_E PF04733.14 CBK25330.2 - 0.14 11.5 2.3 0.44 9.9 0.2 2.6 2 1 0 2 2 2 0 Coatomer epsilon subunit ANAPC3 PF12895.7 CBK25330.2 - 0.98 9.7 4.1 10 6.5 0.1 3.7 4 1 0 4 4 3 0 Anaphase-promoting complex, cyclosome, subunit 3 DUF3381 PF11861.8 CBK25330.2 - 1.5 8.6 6.0 0.45 10.3 1.5 2.3 3 0 0 3 3 3 0 Domain of unknown function (DUF3381) CENP-B_dimeris PF09026.10 CBK25330.2 - 2.7 8.4 8.2 6.2 7.3 8.2 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Pkinase PF00069.25 CBK25332.2 - 1.6e-54 185.1 0.0 6.9e-54 183.0 0.0 1.9 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBK25332.2 - 2.6e-28 99.0 0.0 3.9e-28 98.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 CBK25332.2 - 1.2e-05 25.4 0.0 0.01 15.8 0.0 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kinase-like PF14531.6 CBK25332.2 - 0.001 18.4 0.0 0.0023 17.3 0.0 1.6 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 CBK25332.2 - 0.0015 17.9 0.0 0.0025 17.2 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 CBK25332.2 - 0.0058 16.2 0.1 0.03 13.9 0.0 2.1 3 0 0 3 3 3 1 RIO1 family FTA2 PF13095.6 CBK25332.2 - 0.12 11.9 0.2 0.37 10.4 0.1 1.8 1 1 1 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 zf-CCCH_6 PF18585.1 CBK25333.2 - 0.18 11.7 0.4 0.94 9.4 0.0 2.4 2 0 0 2 2 2 0 Chromatin remodeling factor Mit1 C-terminal Zn finger 2 dDENN PF03455.19 CBK25334.2 - 0.004 17.1 4.1 0.0042 17.0 0.3 3.0 4 0 0 4 4 4 1 dDENN domain DUF2508 PF10704.9 CBK25334.2 - 1.2 9.4 4.3 19 5.5 0.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2508) DENN PF02141.21 CBK25335.2 - 2.3e-38 132.0 2.7 1e-37 129.9 2.7 1.9 1 1 0 1 1 1 1 DENN (AEX-3) domain SPA PF08616.10 CBK25335.2 - 0.0015 18.5 0.2 0.0031 17.4 0.2 1.5 1 0 0 1 1 1 1 Stabilization of polarity axis UCH PF00443.29 CBK25336.2 - 3.7e-17 62.7 0.8 5e-17 62.2 0.8 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase WD40 PF00400.32 CBK25337.2 - 6.2e-07 30.0 0.7 0.17 12.8 0.0 4.6 5 1 0 5 5 5 2 WD domain, G-beta repeat Pkinase PF00069.25 CBK25338.2 - 8.1e-15 54.9 0.0 6.2e-08 32.3 0.0 2.4 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CBK25338.2 - 0.00066 19.0 0.0 0.79 9.0 0.0 2.4 2 0 0 2 2 2 2 Protein tyrosine kinase Seadorna_VP7 PF07387.11 CBK25338.2 - 0.0026 16.9 0.0 0.0064 15.6 0.0 1.6 2 0 0 2 2 2 1 Seadornavirus VP7 MIF4G PF02854.19 CBK25338.2 - 0.025 14.2 0.6 4.5 6.8 0.0 2.3 2 0 0 2 2 2 0 MIF4G domain DUF2689 PF10894.8 CBK25338.2 - 0.031 14.0 0.0 0.073 12.8 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2689) APH PF01636.23 CBK25338.2 - 0.037 14.0 0.0 0.1 12.5 0.0 1.7 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kinase-like PF14531.6 CBK25338.2 - 0.15 11.4 0.3 1.3 8.2 0.0 2.5 3 0 0 3 3 3 0 Kinase-like UCH PF00443.29 CBK25339.2 - 1.5e-13 50.9 0.3 1.8e-13 50.6 0.3 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH PF00443.29 CBK25340.2 - 3e-17 63.0 1.2 3e-17 63.0 1.2 1.8 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase CDC45 PF02724.14 CBK25340.2 - 1.9 6.7 12.2 1.9 6.7 12.2 1.1 1 0 0 1 1 1 0 CDC45-like protein Hid1 PF12722.7 CBK25340.2 - 5.7 4.9 7.4 6.5 4.7 7.4 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Aa_trans PF01490.18 CBK25341.2 - 6.8e-17 61.3 16.5 8.7e-17 60.9 16.5 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Cas_APE2256 PF09651.10 CBK25341.2 - 0.11 12.4 0.2 0.21 11.5 0.2 1.4 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_APE2256) ECSCR PF15820.5 CBK25341.2 - 0.21 11.4 0.6 0.64 9.9 0.6 1.8 1 0 0 1 1 1 0 Endothelial cell-specific chemotaxis regulator CCDC84 PF14968.6 CBK25343.2 - 1.9e-32 113.2 22.5 5e-17 62.6 6.6 3.0 2 1 0 2 2 2 2 Coiled coil protein 84 DUF4972 PF16342.5 CBK25343.2 - 0.092 12.4 0.3 0.2 11.3 0.3 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4972) zf-DBF PF07535.12 CBK25343.2 - 1.6 8.9 7.8 0.2 11.8 2.0 2.2 2 0 0 2 2 2 0 DBF zinc finger DUF647 PF04884.14 CBK25344.2 - 1e-59 202.1 2.0 1.3e-59 201.8 2.0 1.1 1 0 0 1 1 1 1 Vitamin B6 photo-protection and homoeostasis UNC-93 PF05978.16 CBK25345.2 - 2.1e-12 47.0 10.0 2.1e-12 47.0 10.0 3.2 1 1 0 2 2 2 1 Ion channel regulatory protein UNC-93 AgrB PF04647.15 CBK25345.2 - 0.17 11.2 0.0 0.17 11.2 0.0 3.1 3 2 1 4 4 4 0 Accessory gene regulator B LRV_FeS PF05484.11 CBK25345.2 - 0.49 10.4 6.0 1 9.4 6.0 1.5 1 0 0 1 1 1 0 LRV protein FeS4 cluster Transport_MerF PF11431.8 CBK25345.2 - 4.5 7.2 6.5 5 7.1 0.6 3.5 3 0 0 3 3 3 0 Membrane transport protein MerF Arf PF00025.21 CBK25346.2 - 3.6e-78 261.0 0.4 3.9e-78 260.9 0.4 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 CBK25346.2 - 2.7e-15 56.6 0.2 3.7e-15 56.2 0.2 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 CBK25346.2 - 1.1e-14 54.3 0.0 1.3e-14 54.0 0.0 1.0 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.22 CBK25346.2 - 3.2e-14 52.8 0.0 3.6e-14 52.7 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.20 CBK25346.2 - 6.5e-14 51.9 1.8 8.3e-10 38.4 0.4 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.12 CBK25346.2 - 1.1e-10 41.3 0.1 1.4e-10 41.0 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 CBK25346.2 - 9.4e-07 28.9 0.1 1.4e-06 28.4 0.1 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.18 CBK25346.2 - 0.0054 16.1 0.2 0.0096 15.2 0.2 1.5 1 1 0 1 1 1 1 6-phosphofructo-2-kinase CRISPR_Cas2 PF09827.9 CBK25346.2 - 0.015 15.5 0.1 0.03 14.5 0.1 1.5 2 0 0 2 2 2 0 CRISPR associated protein Cas2 cobW PF02492.19 CBK25346.2 - 0.024 14.2 0.3 0.17 11.4 0.0 2.0 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.6 CBK25346.2 - 0.08 13.1 0.0 0.13 12.4 0.0 1.4 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.27 CBK25346.2 - 0.19 12.3 0.3 0.43 11.1 0.3 1.7 1 1 0 1 1 1 0 ABC transporter Arf PF00025.21 CBK25347.2 - 3.6e-78 261.0 0.4 3.9e-78 260.9 0.4 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 CBK25347.2 - 2.7e-15 56.6 0.2 3.7e-15 56.2 0.2 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 CBK25347.2 - 1.1e-14 54.3 0.0 1.3e-14 54.0 0.0 1.0 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.22 CBK25347.2 - 3.2e-14 52.8 0.0 3.6e-14 52.7 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.20 CBK25347.2 - 6.5e-14 51.9 1.8 8.3e-10 38.4 0.4 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.12 CBK25347.2 - 1.1e-10 41.3 0.1 1.4e-10 41.0 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 CBK25347.2 - 9.4e-07 28.9 0.1 1.4e-06 28.4 0.1 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.18 CBK25347.2 - 0.0054 16.1 0.2 0.0096 15.2 0.2 1.5 1 1 0 1 1 1 1 6-phosphofructo-2-kinase CRISPR_Cas2 PF09827.9 CBK25347.2 - 0.015 15.5 0.1 0.03 14.5 0.1 1.5 2 0 0 2 2 2 0 CRISPR associated protein Cas2 cobW PF02492.19 CBK25347.2 - 0.024 14.2 0.3 0.17 11.4 0.0 2.0 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.6 CBK25347.2 - 0.08 13.1 0.0 0.13 12.4 0.0 1.4 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.27 CBK25347.2 - 0.19 12.3 0.3 0.43 11.1 0.3 1.7 1 1 0 1 1 1 0 ABC transporter Arf PF00025.21 CBK25348.2 - 3.6e-78 261.0 0.4 3.9e-78 260.9 0.4 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 CBK25348.2 - 2.7e-15 56.6 0.2 3.7e-15 56.2 0.2 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 CBK25348.2 - 1.1e-14 54.3 0.0 1.3e-14 54.0 0.0 1.0 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.22 CBK25348.2 - 3.2e-14 52.8 0.0 3.6e-14 52.7 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.20 CBK25348.2 - 6.5e-14 51.9 1.8 8.3e-10 38.4 0.4 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.12 CBK25348.2 - 1.1e-10 41.3 0.1 1.4e-10 41.0 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 CBK25348.2 - 9.4e-07 28.9 0.1 1.4e-06 28.4 0.1 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.18 CBK25348.2 - 0.0054 16.1 0.2 0.0096 15.2 0.2 1.5 1 1 0 1 1 1 1 6-phosphofructo-2-kinase CRISPR_Cas2 PF09827.9 CBK25348.2 - 0.015 15.5 0.1 0.03 14.5 0.1 1.5 2 0 0 2 2 2 0 CRISPR associated protein Cas2 cobW PF02492.19 CBK25348.2 - 0.024 14.2 0.3 0.17 11.4 0.0 2.0 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.6 CBK25348.2 - 0.08 13.1 0.0 0.13 12.4 0.0 1.4 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.27 CBK25348.2 - 0.19 12.3 0.3 0.43 11.1 0.3 1.7 1 1 0 1 1 1 0 ABC transporter Vps51 PF08700.11 CBK25349.2 - 5.6e-20 71.2 2.0 5.6e-20 71.2 2.0 2.4 3 0 0 3 3 3 1 Vps51/Vps67 Sec5 PF15469.6 CBK25349.2 - 4.2e-17 62.6 2.2 4.2e-17 62.6 2.2 1.6 1 1 1 2 2 2 1 Exocyst complex component Sec5 Dor1 PF04124.12 CBK25349.2 - 1.5e-10 40.3 6.0 2.9e-10 39.4 5.5 1.7 1 1 1 2 2 2 1 Dor1-like family Vps54_N PF10475.9 CBK25349.2 - 8.9e-09 35.0 5.7 8.9e-09 35.0 5.7 1.6 1 1 1 2 2 2 1 Vacuolar-sorting protein 54, of GARP complex COG2 PF06148.11 CBK25349.2 - 2.5e-06 27.6 9.4 9.6e-06 25.7 3.2 2.5 1 1 0 2 2 2 1 COG (conserved oligomeric Golgi) complex component, COG2 Vps53_N PF04100.12 CBK25349.2 - 0.0011 18.0 4.8 0.0018 17.3 4.8 1.2 1 0 0 1 1 1 1 Vps53-like, N-terminal TF_AP-2 PF03299.14 CBK25349.2 - 0.003 17.6 0.5 0.015 15.3 0.1 2.0 2 0 0 2 2 2 1 Transcription factor AP-2 COG5 PF10392.9 CBK25349.2 - 0.0038 17.4 6.5 0.0083 16.3 1.8 2.6 2 1 0 2 2 2 1 Golgi transport complex subunit 5 Nmad5 PF18757.1 CBK25349.2 - 0.012 15.9 0.1 0.024 14.8 0.1 1.6 1 0 0 1 1 1 0 Nucleotide modification associated domain 5 Phlebovirus_NSM PF07246.11 CBK25349.2 - 0.23 10.8 5.4 0.034 13.5 1.7 1.5 2 0 0 2 2 2 0 Phlebovirus nonstructural protein NS-M Syntaxin-6_N PF09177.11 CBK25349.2 - 0.29 11.7 2.2 2.3 8.8 0.4 2.5 2 0 0 2 2 2 0 Syntaxin 6, N-terminal CENP-F_leu_zip PF10473.9 CBK25349.2 - 0.4 10.7 4.1 0.24 11.4 0.4 2.4 2 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Noelin-1 PF12308.8 CBK25349.2 - 2.9 7.9 5.4 6.1 6.9 0.8 2.6 2 0 0 2 2 2 0 Neurogenesis glycoprotein Cnd1 PF12717.7 CBK25350.2 - 0.18 11.9 0.0 0.61 10.1 0.0 1.9 2 1 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 He_PIG PF05345.12 CBK25352.2 - 3e-09 36.9 3.4 0.00039 20.6 0.1 3.8 4 0 0 4 4 4 2 Putative Ig domain TMEM132D_C PF15706.5 CBK25352.2 - 0.17 11.6 0.9 0.38 10.6 0.9 1.4 1 0 0 1 1 1 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term Baculo_11_kDa PF06143.11 CBK25352.2 - 1.3 8.7 6.1 3.1 7.4 6.1 1.6 1 0 0 1 1 1 0 Baculovirus 11 kDa family DUF1514 PF07438.11 CBK25352.2 - 1.4 8.8 4.8 1.2 9.0 2.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1514) ASFV_J13L PF05568.11 CBK25352.2 - 3.6 7.3 4.9 10 5.8 4.4 1.9 2 0 0 2 2 2 0 African swine fever virus J13L protein TMEM154 PF15102.6 CBK25352.2 - 9.3 6.2 6.9 1.2 9.0 2.6 1.7 2 0 0 2 2 2 0 TMEM154 protein family GCK PF07802.11 CBK25353.2 - 1.4e-10 41.4 5.4 5e-09 36.5 5.4 2.7 1 1 0 1 1 1 1 GCK domain YtxH PF12732.7 CBK25353.2 - 9.2 6.9 6.5 2.8e+02 2.1 6.5 2.7 1 1 0 1 1 1 0 YtxH-like protein PP2C PF00481.21 CBK25354.2 - 8.5e-37 127.2 0.0 3e-36 125.4 0.0 1.8 1 1 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 CBK25354.2 - 0.0018 17.9 0.0 0.012 15.3 0.0 2.3 1 1 0 1 1 1 1 Protein phosphatase 2C DAOA PF15199.6 CBK25354.2 - 0.0051 17.2 0.0 6 7.4 0.0 2.5 2 0 0 2 2 2 2 D-amino acid oxidase activator CholecysA-Rec_N PF09193.10 CBK25354.2 - 0.016 15.2 0.1 0.041 13.9 0.1 1.6 1 0 0 1 1 1 0 Cholecystokinin A receptor, N-terminal Y_phosphatase2 PF03162.13 CBK25355.2 - 1.1e-54 184.5 0.0 1.5e-54 184.0 0.0 1.2 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.6 CBK25355.2 - 4.1e-07 30.2 0.0 4.8e-07 30.0 0.0 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family DSPc PF00782.20 CBK25355.2 - 0.035 13.9 0.0 0.079 12.8 0.0 1.6 2 0 0 2 2 2 0 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 CBK25355.2 - 0.12 12.0 0.0 0.19 11.2 0.0 1.3 1 0 0 1 1 1 0 Protein-tyrosine phosphatase ubiquitin PF00240.23 CBK25356.2 - 0.0071 16.1 0.0 0.0098 15.6 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin family UCH PF00443.29 CBK25357.2 - 7.2e-12 45.3 0.0 5.8e-11 42.4 0.0 1.9 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 CBK25357.2 - 8.9e-06 25.5 0.5 4.2e-05 23.3 0.5 1.9 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Pkinase PF00069.25 CBK25358.2 - 4.9e-22 78.5 0.0 5.7e-22 78.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBK25358.2 - 2.5e-12 46.6 0.0 3.4e-12 46.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CBK25358.2 - 0.066 12.5 0.0 0.13 11.5 0.0 1.5 2 0 0 2 2 2 0 Kinase-like PTH2 PF01981.16 CBK25359.2 - 2.6e-41 140.6 0.2 4.5e-41 139.8 0.2 1.3 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 FAM176 PF14851.6 CBK25359.2 - 0.023 14.4 0.3 0.042 13.5 0.3 1.4 1 0 0 1 1 1 0 FAM176 family GntP_permease PF02447.16 CBK25359.2 - 0.061 12.0 0.0 0.073 11.8 0.0 1.1 1 0 0 1 1 1 0 GntP family permease DUF155 PF02582.14 CBK25359.2 - 0.11 12.6 0.0 0.13 12.3 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised ACR, YagE family COG1723 RAB3GAP2_C PF14656.6 CBK25359.2 - 0.13 10.5 0.4 0.16 10.2 0.4 1.1 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit C-terminus DNA_pol_phi PF04931.13 CBK25359.2 - 0.28 9.2 3.5 0.35 8.9 3.5 1.1 1 0 0 1 1 1 0 DNA polymerase phi V_ATPase_I PF01496.19 CBK25360.2 - 9.8e-259 860.6 15.8 5e-257 855.0 15.8 2.0 1 1 0 1 1 1 1 V-type ATPase 116kDa subunit family DUF4455 PF14643.6 CBK25360.2 - 0.013 14.2 2.0 0.61 8.7 0.5 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4455) PLAT PF01477.23 CBK25361.2 - 3.4e-16 59.8 0.0 6.3e-16 59.0 0.0 1.4 1 0 0 1 1 1 1 PLAT/LH2 domain SpoIIE PF07228.12 CBK25361.2 - 1.1e-06 28.7 0.0 1.8e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) NUC173 PF08161.12 CBK25362.2 - 4.6e-22 78.7 0.9 1.5e-21 77.0 0.3 2.2 2 0 0 2 2 2 1 NUC173 domain CesT PF05932.13 CBK25362.2 - 0.031 14.4 0.2 0.5 10.5 0.1 2.6 2 0 0 2 2 2 0 Tir chaperone protein (CesT) family PUB PF09409.10 CBK25362.2 - 0.072 13.0 0.2 0.22 11.5 0.0 1.9 2 0 0 2 2 2 0 PUB domain FliH PF02108.16 CBK25362.2 - 0.12 12.4 0.0 0.8 9.8 0.0 2.4 2 0 0 2 2 2 0 Flagellar assembly protein FliH MHCassoc_trimer PF08831.10 CBK25362.2 - 0.16 12.0 0.1 0.49 10.4 0.1 1.9 1 0 0 1 1 1 0 Class II MHC-associated invariant chain trimerisation domain CLASP_N PF12348.8 CBK25363.2 - 0.024 14.2 0.9 0.24 10.9 0.1 2.6 2 1 0 2 2 2 0 CLASP N terminal Npa1 PF11707.8 CBK25363.2 - 0.042 13.2 1.0 4.7 6.5 0.6 3.1 2 1 0 2 2 2 0 Ribosome 60S biogenesis N-terminal ParcG PF10274.9 CBK25363.2 - 0.073 13.2 0.3 4 7.5 0.2 2.3 1 1 0 2 2 2 0 Parkin co-regulated protein HEAT PF02985.22 CBK25363.2 - 0.15 12.4 3.2 7.7 7.1 0.1 4.6 5 0 0 5 5 5 0 HEAT repeat DNA_pol_A_exo1 PF01612.20 CBK25364.2 - 5.4e-17 62.1 0.1 8.1e-17 61.5 0.1 1.2 1 0 0 1 1 1 1 3'-5' exonuclease Kinesin PF00225.23 CBK25364.2 - 1.2e-07 31.0 0.0 1.8e-07 30.4 0.0 1.2 1 0 0 1 1 1 1 Kinesin motor domain Kinesin PF00225.23 CBK25365.2 - 3.7e-14 52.4 0.4 9.9e-14 51.0 0.0 1.7 2 0 0 2 2 2 1 Kinesin motor domain KASH_CCD PF14662.6 CBK25365.2 - 3.7e-05 23.6 9.5 5.5e-05 23.1 9.5 1.2 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 or KASH Troponin PF00992.20 CBK25365.2 - 0.00041 20.7 6.2 0.0006 20.1 6.2 1.2 1 0 0 1 1 1 1 Troponin DUF4795 PF16043.5 CBK25365.2 - 0.0015 18.2 4.7 0.0028 17.3 4.7 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4795) GIT_CC PF16559.5 CBK25365.2 - 0.0028 17.5 3.4 0.0064 16.3 3.4 1.6 1 0 0 1 1 1 1 GIT coiled-coil Rho guanine nucleotide exchange factor DivIC PF04977.15 CBK25365.2 - 0.0037 17.0 2.2 0.006 16.3 2.2 1.4 1 0 0 1 1 1 1 Septum formation initiator bZIP_1 PF00170.21 CBK25365.2 - 0.0073 16.4 4.1 0.018 15.1 4.1 1.7 1 0 0 1 1 1 1 bZIP transcription factor Vps53_N PF04100.12 CBK25365.2 - 0.0086 15.1 3.3 0.011 14.7 3.3 1.1 1 0 0 1 1 1 1 Vps53-like, N-terminal Spc7 PF08317.11 CBK25365.2 - 0.013 14.5 7.0 0.017 14.0 7.0 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein RasGAP_C PF03836.15 CBK25365.2 - 0.015 15.5 0.8 0.022 14.9 0.8 1.3 1 0 0 1 1 1 0 RasGAP C-terminus HalX PF08663.10 CBK25365.2 - 0.021 15.1 2.4 0.037 14.4 2.4 1.5 1 0 0 1 1 1 0 HalX domain YabA PF06156.13 CBK25365.2 - 0.032 14.8 3.3 0.067 13.8 3.3 1.6 1 0 0 1 1 1 0 Initiation control protein YabA ZapB PF06005.12 CBK25365.2 - 0.035 14.5 10.1 0.059 13.8 9.0 1.9 1 1 0 1 1 1 0 Cell division protein ZapB APG6_N PF17675.1 CBK25365.2 - 0.04 14.5 7.8 0.059 13.9 7.8 1.2 1 0 0 1 1 1 0 Apg6 coiled-coil region Spc24 PF08286.11 CBK25365.2 - 0.049 13.9 2.8 0.13 12.6 2.8 1.7 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 Mod_r PF07200.13 CBK25365.2 - 0.053 13.6 6.4 0.05 13.7 5.1 1.5 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein DIL PF01843.19 CBK25365.2 - 0.061 13.6 0.2 0.1 12.9 0.2 1.4 1 0 0 1 1 1 0 DIL domain DUF3450 PF11932.8 CBK25365.2 - 0.071 12.4 3.3 0.091 12.0 3.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Baculo_PEP_C PF04513.12 CBK25365.2 - 0.074 13.1 0.8 0.12 12.5 0.8 1.2 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus EMP24_GP25L PF01105.24 CBK25365.2 - 0.088 12.7 2.1 0.13 12.2 2.1 1.3 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD Wtap PF17098.5 CBK25365.2 - 0.09 12.7 6.7 0.12 12.3 6.7 1.2 1 0 0 1 1 1 0 WTAP/Mum2p family DUF1664 PF07889.12 CBK25365.2 - 0.09 12.8 2.8 0.14 12.2 2.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) DUF16 PF01519.16 CBK25365.2 - 0.098 13.2 2.2 0.15 12.6 2.2 1.3 1 0 0 1 1 1 0 Protein of unknown function DUF16 ADIP PF11559.8 CBK25365.2 - 0.1 12.7 6.0 0.15 12.1 6.0 1.2 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding NPV_P10 PF05531.12 CBK25365.2 - 0.12 12.8 0.7 0.25 11.8 0.7 1.5 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein HlyD_2 PF12700.7 CBK25365.2 - 0.16 10.7 2.4 0.21 10.3 2.4 1.1 1 0 0 1 1 1 0 HlyD family secretion protein HALZ PF02183.18 CBK25365.2 - 0.24 11.6 3.1 0.66 10.2 3.1 1.8 1 1 0 1 1 1 0 Homeobox associated leucine zipper TMF_DNA_bd PF12329.8 CBK25365.2 - 0.25 11.3 6.8 0.5 10.4 6.8 1.5 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding TMPIT PF07851.13 CBK25365.2 - 0.26 10.5 2.3 0.32 10.2 2.3 1.1 1 0 0 1 1 1 0 TMPIT-like protein DUF3552 PF12072.8 CBK25365.2 - 0.31 10.4 9.8 0.42 10.0 9.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) TSC22 PF01166.18 CBK25365.2 - 0.35 11.2 6.1 0.49 10.8 4.3 2.1 1 1 0 1 1 1 0 TSC-22/dip/bun family DUF4404 PF14357.6 CBK25365.2 - 1.2 9.8 5.5 7.3 7.3 0.1 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4404) SlyX PF04102.12 CBK25365.2 - 2 9.1 5.0 3.4 8.4 4.5 1.7 1 1 0 1 1 1 0 SlyX DUF1192 PF06698.11 CBK25366.2 - 0.0031 17.5 2.1 0.0031 17.5 2.1 6.4 7 0 0 7 7 7 2 Protein of unknown function (DUF1192) EMP70 PF02990.16 CBK25367.2 - 1.7e-146 489.0 16.6 1.7e-146 489.0 16.6 1.6 1 1 1 2 2 2 1 Endomembrane protein 70 Pro_isomerase PF00160.21 CBK25367.2 - 2.4e-29 102.7 0.0 3.9e-29 102.0 0.0 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Actin PF00022.19 CBK25369.2 - 1.6e-17 63.2 0.0 1.8e-17 63.1 0.0 1.1 1 0 0 1 1 1 1 Actin Actin PF00022.19 CBK25370.2 - 2.5e-20 72.5 0.0 3e-20 72.2 0.0 1.0 1 0 0 1 1 1 1 Actin HEAT PF02985.22 CBK25371.2 - 1.5e-14 52.8 2.4 0.023 14.9 0.0 4.7 4 0 0 4 4 4 4 HEAT repeat HEAT_2 PF13646.6 CBK25371.2 - 3e-08 33.9 1.0 0.035 14.5 0.0 4.2 2 2 2 4 4 4 2 HEAT repeats Adaptin_N PF01602.20 CBK25371.2 - 1.4e-06 27.2 0.6 0.0055 15.3 0.1 2.4 2 1 0 2 2 2 2 Adaptin N terminal region Cnd1 PF12717.7 CBK25371.2 - 2.4e-05 24.4 1.4 0.22 11.5 0.0 3.3 1 1 2 3 3 3 3 non-SMC mitotic condensation complex subunit 1 API5 PF05918.11 CBK25371.2 - 3.3e-05 22.9 0.5 2 7.1 0.0 3.2 3 0 0 3 3 3 3 Apoptosis inhibitory protein 5 (API5) Vac14_Fab1_bd PF12755.7 CBK25371.2 - 0.00034 21.2 0.3 0.095 13.3 0.1 3.2 3 0 0 3 3 3 1 Vacuolar 14 Fab1-binding region CLASP_N PF12348.8 CBK25371.2 - 0.056 13.0 0.1 0.15 11.6 0.0 1.7 2 0 0 2 2 2 0 CLASP N terminal MAD PF05557.13 CBK25372.2 - 3.4e-27 95.1 20.9 2.5e-25 89.0 0.4 3.0 2 1 1 3 3 3 2 Mitotic checkpoint protein FPP PF05911.11 CBK25372.2 - 0.05 11.8 17.5 0.049 11.8 14.1 1.9 2 0 0 2 2 2 0 Filament-like plant protein, long coiled-coil DUF489 PF04356.12 CBK25372.2 - 0.069 13.2 3.6 5.6 6.9 2.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF489) DUF3763 PF12592.8 CBK25372.2 - 0.36 10.9 4.5 7.6 6.7 0.1 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3763) YgaB PF14182.6 CBK25372.2 - 1.3 9.4 0.0 1.3 9.4 0.0 3.4 3 1 1 4 4 4 0 YgaB-like protein DUF4407 PF14362.6 CBK25372.2 - 6.6 6.0 7.5 13 5.0 7.5 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Clat_adaptor_s PF01217.20 CBK25373.2 - 3.3e-28 98.4 0.4 4.2e-28 98.1 0.4 1.1 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Nuc_sug_transp PF04142.15 CBK25374.2 - 2.5e-72 243.7 11.5 2.9e-72 243.5 11.5 1.0 1 0 0 1 1 1 1 Nucleotide-sugar transporter EamA PF00892.20 CBK25374.2 - 4.3e-07 30.2 16.6 8.7e-07 29.2 6.6 2.2 2 0 0 2 2 2 2 EamA-like transporter family PUNUT PF16913.5 CBK25374.2 - 5e-06 26.0 10.1 5e-06 26.0 10.1 1.5 1 1 0 1 1 1 1 Purine nucleobase transmembrane transport EmrE PF13536.6 CBK25374.2 - 1.2e-05 25.1 6.0 1.8e-05 24.5 6.0 1.6 1 1 0 1 1 1 1 Putative multidrug resistance efflux transporter CRT-like PF08627.10 CBK25374.2 - 1.9e-05 23.8 3.6 1.9e-05 23.8 3.6 1.5 2 0 0 2 2 2 1 CRT-like, chloroquine-resistance transporter-like UAA PF08449.11 CBK25374.2 - 4.4e-05 22.8 4.8 5.8e-05 22.4 4.1 1.5 1 1 0 1 1 1 1 UAA transporter family TPT PF03151.16 CBK25374.2 - 0.0022 17.4 8.3 0.0054 16.1 8.2 1.7 1 1 0 1 1 1 1 Triose-phosphate Transporter family Sugar_transport PF06800.12 CBK25374.2 - 0.0039 16.6 6.2 0.0054 16.1 6.2 1.3 1 0 0 1 1 1 1 Sugar transport protein DUF1129 PF06570.11 CBK25374.2 - 0.027 14.0 0.1 0.027 14.0 0.1 1.9 2 1 0 2 2 2 0 Protein of unknown function (DUF1129) Multi_Drug_Res PF00893.19 CBK25374.2 - 0.89 10.3 12.0 0.11 13.2 4.6 2.7 2 1 0 3 3 3 0 Small Multidrug Resistance protein PrgI PF12666.7 CBK25374.2 - 1.7 9.4 5.5 0.36 11.6 0.5 2.5 1 1 2 3 3 3 0 PrgI family protein YwiC PF14256.6 CBK25374.2 - 6.8 7.0 10.6 6.1 7.2 5.2 2.4 1 1 2 3 3 3 0 YwiC-like protein CHCH PF06747.13 CBK25375.2 - 0.0004 20.4 0.4 0.00057 19.9 0.4 1.2 1 0 0 1 1 1 1 CHCH domain CX9C PF16860.5 CBK25375.2 - 0.062 13.3 0.0 0.093 12.8 0.0 1.3 1 0 0 1 1 1 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, GCK PF07802.11 CBK25375.2 - 0.075 13.5 0.8 1 9.9 0.2 2.1 1 1 1 2 2 2 0 GCK domain LSM PF01423.22 CBK25377.2 - 2e-18 65.8 1.4 2.6e-18 65.5 1.4 1.2 1 0 0 1 1 1 1 LSM domain BPL_C PF02237.17 CBK25377.2 - 0.0041 17.0 0.8 0.0069 16.3 0.8 1.4 1 0 0 1 1 1 1 Biotin protein ligase C terminal domain Fumble PF03630.14 CBK25378.2 - 9.7e-101 337.2 0.1 1.2e-100 336.9 0.1 1.0 1 0 0 1 1 1 1 Fumble Mob1_phocein PF03637.17 CBK25379.2 - 2.9e-39 134.8 1.9 3.4e-39 134.6 1.9 1.1 1 0 0 1 1 1 1 Mob1/phocein family C8 PF08742.11 CBK25379.2 - 0.092 13.2 1.6 0.22 12.0 0.3 2.0 2 0 0 2 2 2 0 C8 domain Maf PF02545.14 CBK25380.2 - 2e-18 66.8 0.0 2.6e-18 66.4 0.0 1.1 1 0 0 1 1 1 1 Maf-like protein zf-Sec23_Sec24 PF04810.15 CBK25380.2 - 0.26 11.4 3.0 0.73 9.9 3.0 1.7 1 1 0 1 1 1 0 Sec23/Sec24 zinc finger VWA_2 PF13519.6 CBK25381.2 - 9e-06 26.3 0.0 4.7e-05 24.0 0.0 1.9 2 1 0 2 2 2 1 von Willebrand factor type A domain Methyltransf_33 PF10017.9 CBK25381.2 - 0.099 11.8 0.0 0.15 11.1 0.0 1.3 1 1 0 1 1 1 0 Histidine-specific methyltransferase, SAM-dependent TPR_14 PF13428.6 CBK25382.2 - 0.00037 21.1 0.1 3 8.9 0.0 4.7 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_19 PF14559.6 CBK25382.2 - 0.0024 18.3 0.0 0.053 14.0 0.0 2.6 2 1 0 2 2 2 1 Tetratricopeptide repeat tRNA-synt_2 PF00152.20 CBK25383.2 - 1.4e-81 274.0 0.1 1.8e-81 273.7 0.1 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 CBK25383.2 - 1.2e-10 41.3 0.1 2.2e-10 40.4 0.1 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 CBK25383.2 - 0.0007 19.1 0.2 0.0056 16.2 0.0 2.2 2 0 0 2 2 2 1 tRNA synthetases class II core domain (F) ATP-synt_ab PF00006.25 CBK25384.2 - 4.6e-106 353.2 0.0 6.9e-106 352.7 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_Xtn PF16886.5 CBK25384.2 - 4.7e-37 126.5 0.0 8.4e-37 125.7 0.0 1.4 1 0 0 1 1 1 1 ATPsynthase alpha/beta subunit N-term extension ATP-synt_ab_N PF02874.23 CBK25384.2 - 2.7e-13 50.2 2.2 1e-12 48.4 0.3 2.7 2 0 0 2 2 2 1 ATP synthase alpha/beta family, beta-barrel domain AAA_18 PF13238.6 CBK25384.2 - 0.17 12.5 0.2 0.74 10.4 0.0 2.0 2 0 0 2 2 2 0 AAA domain Ribosomal_L24e PF01246.20 CBK25385.2 - 4e-27 94.2 1.1 4e-27 94.2 1.1 1.6 2 1 0 2 2 2 1 Ribosomal protein L24e SANT_DAMP1_like PF16282.5 CBK25386.2 - 6e-23 80.9 1.0 1.5e-22 79.6 1.0 1.7 1 0 0 1 1 1 1 SANT/Myb-like domain of DAMP1 Ribosomal_L24e PF01246.20 CBK25387.2 - 3.1e-27 94.6 1.1 3.1e-27 94.6 1.1 1.6 2 1 0 2 2 2 1 Ribosomal protein L24e ATP-synt_ab PF00006.25 CBK25388.2 - 4.6e-106 353.2 0.0 6.9e-106 352.7 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_Xtn PF16886.5 CBK25388.2 - 4.7e-37 126.5 0.0 8.4e-37 125.7 0.0 1.4 1 0 0 1 1 1 1 ATPsynthase alpha/beta subunit N-term extension ATP-synt_ab_N PF02874.23 CBK25388.2 - 2.7e-13 50.2 2.2 1e-12 48.4 0.3 2.7 2 0 0 2 2 2 1 ATP synthase alpha/beta family, beta-barrel domain AAA_18 PF13238.6 CBK25388.2 - 0.17 12.5 0.2 0.74 10.4 0.0 2.0 2 0 0 2 2 2 0 AAA domain DUF3199 PF11436.8 CBK25389.2 - 0.046 13.7 9.5 2.3 8.3 0.2 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3199) SH2 PF00017.24 CBK25389.2 - 0.049 13.7 0.0 0.33 11.1 0.0 2.5 1 1 0 1 1 1 0 SH2 domain Presenilin PF01080.17 CBK25389.2 - 7.6 5.2 12.3 11 4.7 12.3 1.2 1 0 0 1 1 1 0 Presenilin Fer2 PF00111.27 CBK25390.2 - 1.1e-10 41.3 0.5 1.1e-10 41.3 0.5 1.8 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain TPR_2 PF07719.17 CBK25392.2 - 5.7e-07 29.2 0.1 0.18 12.0 0.0 3.6 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_20 PF14561.6 CBK25392.2 - 3.4e-05 24.1 0.8 0.00021 21.6 0.2 2.0 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 CBK25392.2 - 4.1e-05 24.1 0.1 0.24 12.3 0.0 2.9 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 CBK25392.2 - 4.8e-05 23.0 2.9 3.5 7.6 0.0 3.8 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_11 PF13414.6 CBK25392.2 - 0.00011 21.9 1.6 0.17 11.6 0.0 3.5 3 1 1 4 4 4 2 TPR repeat TPR_19 PF14559.6 CBK25392.2 - 0.00018 22.0 0.3 0.00046 20.6 0.1 1.8 2 0 0 2 2 2 1 Tetratricopeptide repeat MIT PF04212.18 CBK25392.2 - 0.0037 17.3 0.3 0.43 10.7 0.0 2.8 3 0 0 3 3 3 1 MIT (microtubule interacting and transport) domain TPR_8 PF13181.6 CBK25392.2 - 0.0041 17.2 0.4 2.1 8.8 0.0 3.6 4 0 0 4 4 4 1 Tetratricopeptide repeat NARP1 PF12569.8 CBK25392.2 - 0.007 15.3 0.1 0.0075 15.2 0.1 1.1 1 0 0 1 1 1 1 NMDA receptor-regulated protein 1 TPR_10 PF13374.6 CBK25392.2 - 0.011 15.6 0.0 4.3 7.4 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_17 PF13431.6 CBK25392.2 - 0.028 14.8 0.2 0.6 10.6 0.0 2.5 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.6 CBK25392.2 - 0.07 13.2 0.5 12 6.2 0.0 3.2 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF2373 PF10180.9 CBK25393.2 - 5.2e-22 77.5 1.9 5.2e-22 77.5 1.9 1.8 2 0 0 2 2 2 1 Uncharacterised conserved protein (DUF2373) NLRC4_HD2 PF17776.1 CBK25393.2 - 0.06 13.9 0.5 0.22 12.0 0.0 2.0 2 0 0 2 2 2 0 NLRC4 helical domain HD2 DDA1 PF10172.9 CBK25393.2 - 1.8 8.9 6.6 15 6.0 0.2 3.7 2 1 2 4 4 4 0 Det1 complexing ubiquitin ligase DUF1674 PF07896.12 CBK25394.2 - 6.4e-10 39.4 6.5 2.3e-09 37.6 6.5 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF1674) Kelch_1 PF01344.25 CBK25394.2 - 0.096 12.3 0.0 0.2 11.3 0.0 1.5 1 0 0 1 1 1 0 Kelch motif CoA_binding PF02629.19 CBK25395.2 - 7.8e-30 103.4 1.3 7.8e-30 103.4 1.3 2.5 3 0 0 3 3 3 1 CoA binding domain Ligase_CoA PF00549.19 CBK25395.2 - 2.3e-23 82.7 0.1 4.6e-23 81.7 0.1 1.5 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.6 CBK25395.2 - 7.1e-10 38.8 0.0 1.5e-09 37.8 0.0 1.5 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.6 CBK25395.2 - 0.00011 22.6 0.0 0.00024 21.6 0.0 1.6 1 0 0 1 1 1 1 CoA binding domain GFO_IDH_MocA PF01408.22 CBK25395.2 - 0.031 15.1 0.1 0.085 13.7 0.1 1.7 2 0 0 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold SseB PF07179.12 CBK25395.2 - 0.16 12.2 0.0 0.24 11.7 0.0 1.3 1 0 0 1 1 1 0 SseB protein N-terminal domain Ribosomal_L21e PF01157.18 CBK25396.2 - 3.4e-31 107.1 1.9 6.2e-31 106.3 1.9 1.4 1 0 0 1 1 1 1 Ribosomal protein L21e Put_Phosphatase PF06888.12 CBK25396.2 - 0.054 12.9 0.0 0.085 12.2 0.0 1.3 1 0 0 1 1 1 0 Putative Phosphatase MSP1b PF03429.13 CBK25396.2 - 0.17 9.9 0.0 0.2 9.7 0.0 1.1 1 0 0 1 1 1 0 Major surface protein 1B NFACT-R_1 PF05670.13 CBK25397.2 - 2.5e-36 124.6 0.0 3.4e-36 124.2 0.0 1.2 1 0 0 1 1 1 1 NFACT protein RNA binding domain ketoacyl-synt PF00109.26 CBK25398.2 - 6.8e-75 251.9 0.3 2e-74 250.3 0.0 1.9 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.21 CBK25398.2 - 9.4e-61 206.0 0.0 1.8e-60 205.1 0.0 1.4 1 0 0 1 1 1 1 Acyl transferase domain KR PF08659.10 CBK25398.2 - 2.8e-51 174.0 0.2 1.4e-48 165.2 0.0 2.6 2 0 0 2 2 2 1 KR domain Aminotran_1_2 PF00155.21 CBK25398.2 - 1.5e-47 162.6 0.0 2.8e-47 161.6 0.0 1.5 1 0 0 1 1 1 1 Aminotransferase class I and II PS-DH PF14765.6 CBK25398.2 - 7.4e-41 140.3 0.0 1.2e-40 139.6 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase Ketoacyl-synt_C PF02801.22 CBK25398.2 - 5.4e-36 123.2 0.4 1.4e-35 121.9 0.4 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain ADH_zinc_N PF00107.26 CBK25398.2 - 4.3e-24 85.0 0.0 3.7e-23 81.9 0.0 2.7 2 0 0 2 2 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 CBK25398.2 - 9.8e-16 59.0 0.0 3.5e-15 57.2 0.0 2.1 1 0 0 1 1 1 1 Zinc-binding dehydrogenase KAsynt_C_assoc PF16197.5 CBK25398.2 - 1.6e-12 47.8 0.0 4e-12 46.6 0.0 1.7 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension ADH_N PF08240.12 CBK25398.2 - 2.5e-07 30.6 2.6 7.2e-07 29.1 0.2 2.8 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain adh_short PF00106.25 CBK25398.2 - 1.5e-06 27.8 0.2 0.004 16.6 0.0 2.6 2 0 0 2 2 2 2 short chain dehydrogenase PP-binding PF00550.25 CBK25398.2 - 3.1e-06 27.4 0.2 1.4e-05 25.3 0.3 2.2 2 0 0 2 2 1 1 Phosphopantetheine attachment site ELFV_dehydrog PF00208.21 CBK25398.2 - 4.5e-06 26.6 1.3 0.024 14.4 0.0 2.6 2 0 0 2 2 2 2 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase AlaDh_PNT_C PF01262.21 CBK25398.2 - 2.6e-05 23.6 2.4 0.00027 20.3 0.8 2.5 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain adh_short_C2 PF13561.6 CBK25398.2 - 5.4e-05 22.9 0.0 0.069 12.7 0.0 2.6 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase Aminotran_5 PF00266.19 CBK25398.2 - 0.00019 20.5 0.0 0.00092 18.3 0.0 2.0 2 0 0 2 2 2 1 Aminotransferase class-V Thiolase_N PF00108.23 CBK25398.2 - 0.00031 20.2 0.0 0.00065 19.1 0.0 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain SAT PF16073.5 CBK25398.2 - 0.002 17.9 0.6 0.63 9.7 0.1 3.2 3 0 0 3 3 3 1 Starter unit:ACP transacylase in aflatoxin biosynthesis Epimerase PF01370.21 CBK25398.2 - 0.057 12.9 0.1 3.9 6.8 0.1 2.6 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family Cys_Met_Meta_PP PF01053.20 CBK25398.2 - 0.059 11.9 0.0 0.12 10.9 0.0 1.4 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme DapB_N PF01113.20 CBK25398.2 - 0.11 12.6 0.1 1.1 9.4 0.0 2.7 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus Peptidase_C1 PF00112.23 CBK25399.2 - 5.5e-100 333.9 21.2 1.6e-56 191.8 6.4 2.1 2 0 0 2 2 2 2 Papain family cysteine protease Octopine_DH PF02317.17 CBK25399.2 - 0.08 13.0 0.0 0.52 10.4 0.0 2.0 2 0 0 2 2 2 0 NAD/NADP octopine/nopaline dehydrogenase, alpha-helical domain Peptidase_C1_2 PF03051.15 CBK25399.2 - 0.083 11.7 11.4 0.19 10.4 0.8 3.3 4 0 0 4 4 4 0 Peptidase C1-like family Methyltransf_15 PF09445.10 CBK25400.2 - 1.2e-18 67.2 0.1 2.2e-18 66.4 0.1 1.4 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Cons_hypoth95 PF03602.15 CBK25400.2 - 4.4e-07 29.7 0.0 6.4e-07 29.2 0.0 1.3 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltr_RsmB-F PF01189.17 CBK25400.2 - 0.00031 20.5 0.0 0.0005 19.8 0.0 1.2 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F RrnaAD PF00398.20 CBK25400.2 - 0.0011 18.1 0.0 0.0019 17.4 0.0 1.3 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Met_10 PF02475.16 CBK25400.2 - 0.0097 15.7 0.0 0.012 15.4 0.0 1.3 1 0 0 1 1 1 1 Met-10+ like-protein DJ-1_PfpI PF01965.24 CBK25401.2 - 2.2e-08 34.1 0.6 1.1e-07 31.8 0.6 2.2 1 1 0 1 1 1 1 DJ-1/PfpI family GATase_3 PF07685.14 CBK25401.2 - 0.0074 15.9 0.0 0.015 14.9 0.0 1.5 1 1 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain GATase PF00117.28 CBK25401.2 - 0.042 13.6 0.0 0.062 13.1 0.0 1.3 1 0 0 1 1 1 0 Glutamine amidotransferase class-I G-patch_2 PF12656.7 CBK25402.2 - 2.2e-12 46.9 0.0 4.1e-12 46.0 0.0 1.4 1 0 0 1 1 1 1 G-patch domain zf-UBR PF02207.20 CBK25405.2 - 6.9e-16 58.2 21.3 6.9e-16 58.2 21.3 2.2 2 0 0 2 2 2 1 Putative zinc finger in N-recognin (UBR box) Amidohydro_1 PF01979.20 CBK25406.2 - 8.7e-24 84.5 1.0 1.5e-23 83.7 1.0 1.4 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 CBK25406.2 - 2.2e-08 34.0 0.0 4e-05 23.3 0.0 2.3 2 0 0 2 2 2 2 Amidohydrolase family DNA_pol_A PF00476.20 CBK25407.2 - 2.1e-76 257.4 0.0 5.4e-75 252.8 0.0 2.7 2 1 0 2 2 2 1 DNA polymerase family A Integrase_Zn PF02022.19 CBK25407.2 - 0.014 15.3 0.0 0.042 13.8 0.0 1.8 1 0 0 1 1 1 0 Integrase Zinc binding domain TB2_DP1_HVA22 PF03134.19 CBK25408.2 - 6e-15 54.9 4.0 7.4e-15 54.6 4.0 1.1 1 0 0 1 1 1 1 TB2/DP1, HVA22 family Ribosomal_L6e PF01159.19 CBK25409.2 - 5.5e-25 88.1 0.2 3.5e-12 46.8 0.0 2.1 1 1 1 2 2 2 2 Ribosomal protein L6e CPBP PF02517.16 CBK25410.2 - 2.7e-12 46.9 3.1 2.7e-12 46.9 3.1 1.9 1 1 1 2 2 2 1 CPBP intramembrane metalloprotease ODV-E18 PF10717.9 CBK25411.2 - 0.0014 18.4 0.9 0.0016 18.3 0.9 1.1 1 0 0 1 1 1 1 Occlusion-derived virus envelope protein ODV-E18 TPPK_C PF12555.8 CBK25411.2 - 0.0074 16.3 1.8 0.011 15.7 1.8 1.2 1 0 0 1 1 1 1 Thiamine pyrophosphokinase C terminal TMEM192 PF14802.6 CBK25411.2 - 0.037 13.1 1.1 0.041 13.0 1.1 1.0 1 0 0 1 1 1 0 TMEM192 family CrgA PF06781.12 CBK25411.2 - 0.087 12.9 0.2 0.091 12.8 0.2 1.1 1 0 0 1 1 1 0 Cell division protein CrgA DUF2768 PF10966.8 CBK25411.2 - 0.13 12.7 7.3 0.11 12.9 6.7 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2768) RIFIN PF02009.16 CBK25411.2 - 0.66 9.8 3.0 0.62 9.9 3.0 1.0 1 0 0 1 1 1 0 Rifin Syndecan PF01034.20 CBK25411.2 - 0.76 9.7 5.2 0.95 9.4 5.2 1.2 1 0 0 1 1 1 0 Syndecan domain Baculo_11_kDa PF06143.11 CBK25411.2 - 0.77 9.4 6.0 0.98 9.0 6.0 1.2 1 0 0 1 1 1 0 Baculovirus 11 kDa family SNRNP27 PF08648.12 CBK25412.2 - 1.1e-09 38.1 0.2 1.1e-09 38.1 0.2 1.7 2 0 0 2 2 2 1 U4/U6.U5 small nuclear ribonucleoproteins Corona_nucleoca PF00937.18 CBK25412.2 - 0.011 14.8 11.1 0.013 14.6 11.1 1.1 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein THRAP3_BCLAF1 PF15440.6 CBK25412.2 - 0.042 12.9 25.2 0.052 12.6 25.2 1.1 1 0 0 1 1 1 0 THRAP3/BCLAF1 family DUF1676 PF07898.13 CBK25414.2 - 0.083 12.9 2.4 0.093 12.8 2.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1676) DUF913 PF06025.12 CBK25414.2 - 0.37 9.7 4.7 0.37 9.7 4.7 1.0 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) PBP1_TM PF14812.6 CBK25414.2 - 0.66 10.4 8.0 0.52 10.7 6.7 1.6 1 1 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF3332 PF11810.8 CBK25414.2 - 3.7 7.1 5.6 5.5 6.6 5.6 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF3332) RabGAP-TBC PF00566.18 CBK25415.2 - 4.6e-05 23.2 0.3 0.0094 15.6 0.0 2.1 2 0 0 2 2 2 2 Rab-GTPase-TBC domain Beach PF02138.18 CBK25417.2 - 9.3e-39 133.5 4.9 1.4e-38 132.9 3.2 2.2 2 1 0 2 2 2 1 Beige/BEACH domain Pkinase PF00069.25 CBK25417.2 - 0.0027 17.1 0.2 0.0043 16.5 0.2 1.2 1 0 0 1 1 1 1 Protein kinase domain WD40 PF00400.32 CBK25418.2 - 1.3e-08 35.3 1.4 0.0014 19.4 0.2 3.4 3 0 0 3 3 3 2 WD domain, G-beta repeat TPR_1 PF00515.28 CBK25419.2 - 2e-23 81.2 3.5 0.002 17.9 0.0 8.1 8 0 0 8 8 7 6 Tetratricopeptide repeat TPR_2 PF07719.17 CBK25419.2 - 3.2e-20 70.6 15.5 0.001 19.0 0.0 9.0 10 0 0 10 10 9 5 Tetratricopeptide repeat TPR_8 PF13181.6 CBK25419.2 - 4.9e-18 63.8 10.8 0.0031 17.6 0.0 9.7 11 0 0 11 11 10 4 Tetratricopeptide repeat TPR_17 PF13431.6 CBK25419.2 - 3.2e-15 55.3 7.2 0.0085 16.4 0.0 8.2 9 0 0 9 9 8 2 Tetratricopeptide repeat TPR_16 PF13432.6 CBK25419.2 - 1.2e-14 54.6 0.8 0.017 15.8 0.0 5.4 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_9 PF13371.6 CBK25419.2 - 2.5e-14 53.2 2.5 2e-05 24.7 0.0 4.9 5 0 0 5 5 4 3 Tetratricopeptide repeat TPR_19 PF14559.6 CBK25419.2 - 7.7e-14 52.0 3.7 0.1 13.1 0.0 6.9 5 1 2 7 7 7 4 Tetratricopeptide repeat TPR_11 PF13414.6 CBK25419.2 - 2.3e-11 43.2 14.8 2.9e-06 26.9 0.0 7.6 7 2 2 9 9 9 2 TPR repeat TPR_7 PF13176.6 CBK25419.2 - 4.2e-09 35.8 2.3 0.25 11.5 0.1 6.1 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.6 CBK25419.2 - 4.8e-09 36.3 6.9 0.23 12.4 0.0 7.7 5 2 4 9 9 9 2 Tetratricopeptide repeat TPR_10 PF13374.6 CBK25419.2 - 3.6e-07 29.8 0.4 1.2 9.1 0.0 4.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 CBK25419.2 - 7.2e-07 29.4 12.3 0.0011 19.1 0.6 7.0 5 2 1 6 6 6 1 Tetratricopeptide repeat TPR_6 PF13174.6 CBK25419.2 - 1.3e-06 28.6 6.4 1.3 9.8 0.0 7.8 8 1 1 9 9 8 1 Tetratricopeptide repeat TPR_15 PF13429.6 CBK25419.2 - 1.5e-06 27.7 2.8 0.00012 21.4 0.1 3.4 2 1 0 3 3 3 1 Tetratricopeptide repeat ANAPC3 PF12895.7 CBK25419.2 - 0.00064 19.9 19.6 0.052 13.8 0.6 6.0 4 2 3 7 7 7 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_MalT PF17874.1 CBK25419.2 - 0.0084 15.5 0.1 0.28 10.5 0.0 2.5 1 1 1 2 2 2 2 MalT-like TPR region TPR_4 PF07721.14 CBK25419.2 - 0.01 16.4 0.0 1.7 9.5 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF4810 PF16068.5 CBK25419.2 - 0.088 13.4 0.5 1.3 9.6 0.0 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF4810) TOM20_plant PF06552.12 CBK25419.2 - 0.13 12.0 0.1 9.8 5.9 0.0 3.0 2 1 1 3 3 3 0 Plant specific mitochondrial import receptor subunit TOM20 Fis1_TPR_C PF14853.6 CBK25419.2 - 0.74 9.9 9.6 3.6 7.7 0.1 5.0 5 0 0 5 5 5 0 Fis1 C-terminal tetratricopeptide repeat HA2 PF04408.23 CBK25420.2 - 3.7e-22 78.7 0.1 9.9e-22 77.3 0.1 1.8 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.31 CBK25420.2 - 5.2e-13 49.3 0.0 1.2e-12 48.2 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.16 CBK25420.2 - 9e-08 32.4 0.0 3.4e-07 30.5 0.0 2.0 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.29 CBK25420.2 - 0.11 12.2 0.0 0.23 11.2 0.0 1.5 1 0 0 1 1 1 0 DEAD/DEAH box helicase Actin PF00022.19 CBK25421.2 - 7.1e-105 350.9 0.0 2.7e-104 349.0 0.0 1.7 1 1 0 1 1 1 1 Actin Actin_micro PF17003.5 CBK25421.2 - 0.0067 15.7 0.0 0.35 10.0 0.0 2.1 2 0 0 2 2 2 2 Putative actin-like family MreB_Mbl PF06723.13 CBK25421.2 - 0.16 10.8 0.0 7.6 5.2 0.0 2.7 2 1 0 2 2 2 0 MreB/Mbl protein EIF_2_alpha PF07541.12 CBK25423.2 - 2.2e-24 85.8 0.0 3.9e-24 85.0 0.0 1.4 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 2 alpha subunit S1 PF00575.23 CBK25423.2 - 1.5e-14 54.1 0.4 2.6e-14 53.3 0.4 1.5 1 0 0 1 1 1 1 S1 RNA binding domain DnaJ PF00226.31 CBK25424.2 - 3e-23 81.7 1.7 4e-23 81.3 1.7 1.2 1 0 0 1 1 1 1 DnaJ domain DUF1706 PF08020.11 CBK25424.2 - 0.021 14.7 0.1 0.023 14.6 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1706) DUF2654 PF10849.8 CBK25424.2 - 0.076 13.2 0.1 0.12 12.6 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2654) FRB_dom PF08771.11 CBK25424.2 - 0.09 13.2 0.1 0.11 12.9 0.1 1.1 1 0 0 1 1 1 0 FKBP12-rapamycin binding domain DUF3395 PF11875.8 CBK25426.2 - 3.1e-26 92.1 0.0 3.6e-26 91.9 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3395) Lectin_leg-like PF03388.13 CBK25427.2 - 6.6e-39 133.6 1.2 8.5e-39 133.2 1.2 1.1 1 0 0 1 1 1 1 Legume-like lectin family Lectin_legB PF00139.19 CBK25427.2 - 1.3e-09 38.0 0.1 6.8e-09 35.6 0.1 1.9 1 1 0 1 1 1 1 Legume lectin domain Bact_lectin PF18483.1 CBK25427.2 - 1.2e-08 35.2 0.6 1.8e-08 34.6 0.6 1.2 1 0 0 1 1 1 1 Bacterial lectin NDUFV3 PF15880.5 CBK25427.2 - 0.0036 17.3 0.3 0.0074 16.3 0.3 1.5 1 0 0 1 1 1 1 NADH dehydrogenase [ubiquinone] flavoprotein 3, mitochondrial CIA30 PF08547.12 CBK25427.2 - 0.12 12.4 0.2 0.33 10.9 0.1 1.8 2 0 0 2 2 2 0 Complex I intermediate-associated protein 30 (CIA30) Oxidored_q2 PF00420.24 CBK25428.2 - 0.059 13.0 0.1 0.099 12.3 0.1 1.3 1 0 0 1 1 1 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L Ribosomal_L23 PF00276.20 CBK25430.2 - 1.3e-15 57.5 2.9 4.8e-15 55.7 2.9 1.7 1 1 0 1 1 1 1 Ribosomal protein L23 IL31 PF15209.6 CBK25430.2 - 0.046 13.5 0.2 0.054 13.3 0.2 1.1 1 0 0 1 1 1 0 Interleukin 31 Peptidase_C1 PF00112.23 CBK25431.2 - 1e-11 45.4 0.0 2.5e-11 44.1 0.0 1.6 1 0 0 1 1 1 1 Papain family cysteine protease TA_inhibitor PF17574.2 CBK25431.2 - 5.2e-09 36.0 0.0 0.0041 17.1 0.0 3.8 4 0 0 4 4 4 2 Inhibitor of toxin/antitoxin system (Gp4.5) Inhibitor_I29 PF08246.12 CBK25431.2 - 0.00027 21.3 2.8 0.001 19.5 0.3 2.4 2 0 0 2 2 2 1 Cathepsin propeptide inhibitor domain (I29) Baculo_RING PF05883.11 CBK25431.2 - 1.9 8.5 3.8 3.6 7.6 0.3 2.6 2 0 0 2 2 2 0 Baculovirus U-box/Ring-like domain DUF759 PF05537.11 CBK25432.2 - 0.06 12.2 0.0 0.068 12.0 0.0 1.0 1 0 0 1 1 1 0 Borrelia burgdorferi protein of unknown function (DUF759) PelD_GGDEF PF16963.5 CBK25432.2 - 0.12 12.2 0.0 0.14 11.9 0.0 1.1 1 0 0 1 1 1 0 PelD GGDEF domain Carboxyl_trans PF01039.22 CBK25433.2 - 4.9e-190 632.4 0.1 5.8e-190 632.1 0.1 1.0 1 0 0 1 1 1 1 Carboxyl transferase domain MdcE PF06833.11 CBK25433.2 - 0.0093 15.5 0.0 0.03 13.8 0.0 1.8 3 0 0 3 3 3 1 Malonate decarboxylase gamma subunit (MdcE) Mucin-like PF16058.5 CBK25434.2 - 1.6 8.9 5.8 0.5 10.5 0.2 2.5 2 1 0 2 2 2 0 Mucin-like DNA_topoisoIV PF00521.20 CBK25436.2 - 9.5e-123 410.2 0.0 9.5e-123 410.2 0.0 1.6 2 0 0 2 2 2 1 DNA gyrase/topoisomerase IV, subunit A TOPRIM_C PF16898.5 CBK25436.2 - 2.8e-44 150.5 3.8 1.1e-43 148.5 3.8 2.2 1 0 0 1 1 1 1 C-terminal associated domain of TOPRIM DNA_gyraseB PF00204.25 CBK25436.2 - 1.1e-17 64.1 1.2 3.2e-17 62.6 1.2 1.8 1 0 0 1 1 1 1 DNA gyrase B HATPase_c PF02518.26 CBK25436.2 - 6e-13 49.3 0.0 1.8e-12 47.7 0.0 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Toprim PF01751.22 CBK25436.2 - 4.1e-06 27.0 0.0 1.5e-05 25.2 0.0 2.0 1 0 0 1 1 1 1 Toprim domain Collagen PF01391.18 CBK25438.2 - 0.00018 21.2 10.1 0.00018 21.2 10.1 2.5 2 1 1 3 3 3 2 Collagen triple helix repeat (20 copies) Helicase_C_2 PF13307.6 CBK25439.2 - 1.1e-51 175.4 0.2 6.5e-51 172.9 0.0 2.3 2 0 0 2 2 2 1 Helicase C-terminal domain DEAD_2 PF06733.15 CBK25439.2 - 2.4e-34 118.5 4.3 5.6e-34 117.3 4.3 1.7 1 0 0 1 1 1 1 DEAD_2 DEAD PF00270.29 CBK25439.2 - 6.3e-05 22.8 0.1 0.0046 16.7 0.0 3.0 3 0 0 3 3 3 1 DEAD/DEAH box helicase ResIII PF04851.15 CBK25439.2 - 0.0002 21.4 0.1 0.038 14.0 0.0 2.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit GAS PF13851.6 CBK25439.2 - 0.018 14.4 3.9 0.052 12.9 0.2 2.3 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding AAA_11 PF13086.6 CBK25439.2 - 0.022 14.6 1.4 0.053 13.3 1.4 1.7 1 1 0 1 1 1 0 AAA domain MORN_2 PF07661.13 CBK25440.2 - 0.086 13.1 4.1 0.22 11.9 0.6 3.3 3 0 0 3 3 3 0 MORN repeat variant Aldo_ket_red PF00248.21 CBK25441.2 - 6e-47 160.2 0.0 9.7e-47 159.6 0.0 1.3 1 1 0 1 1 1 1 Aldo/keto reductase family Flot PF15975.5 CBK25442.2 - 0.031 14.5 5.7 0.069 13.3 5.7 1.5 1 0 0 1 1 1 0 Flotillin DUF2796 PF10986.8 CBK25442.2 - 0.13 12.2 5.8 1.2 9.1 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2796) UQ_con PF00179.26 CBK25443.2 - 6.4e-07 29.1 0.1 7.4e-07 28.9 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Cactin_mid PF10312.9 CBK25445.2 - 0.061 13.0 0.1 0.074 12.8 0.1 1.1 1 0 0 1 1 1 0 Conserved mid region of cactin Utp21 PF04192.12 CBK25446.2 - 5e-35 121.1 0.0 4.6e-34 117.9 0.0 2.0 1 1 0 1 1 1 1 Utp21 specific WD40 associated putative domain WD40 PF00400.32 CBK25446.2 - 9.1e-14 51.6 7.4 2.8 8.9 0.0 9.1 9 0 0 9 9 9 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBK25446.2 - 6.5e-09 36.0 0.0 0.0089 16.3 0.0 4.7 4 1 1 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 CBK25446.2 - 0.0066 15.2 0.0 2.6 6.6 0.0 3.3 2 1 1 3 3 3 1 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.16 CBK25446.2 - 0.19 10.2 0.0 0.33 9.4 0.0 1.3 1 0 0 1 1 1 0 Cytochrome D1 heme domain zf-C2H2_4 PF13894.6 CBK25447.2 - 0.75 10.8 17.0 4 8.6 1.5 3.8 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2_6 PF13912.6 CBK25447.2 - 1.9 8.6 0.0 1.9 8.6 0.0 3.3 4 0 0 4 4 4 0 C2H2-type zinc finger He_PIG PF05345.12 CBK25448.2 - 0.00024 21.2 0.0 0.0011 19.1 0.0 2.1 1 0 0 1 1 1 1 Putative Ig domain Sushi PF00084.20 CBK25448.2 - 0.13 12.8 3.3 0.34 11.5 0.4 2.5 2 0 0 2 2 2 0 Sushi repeat (SCR repeat) TMEM154 PF15102.6 CBK25448.2 - 0.28 11.1 1.0 0.63 9.9 1.0 1.5 1 0 0 1 1 1 0 TMEM154 protein family Peptidase_M24 PF00557.24 CBK25449.2 - 3.6e-40 137.9 0.0 4.3e-40 137.6 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 DUF4710 PF15828.5 CBK25449.2 - 0.036 14.2 8.7 0.89 9.7 6.7 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4710) PBP1_TM PF14812.6 CBK25449.2 - 2.9 8.3 9.0 0.11 12.9 2.2 1.9 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Na_H_antiporter PF03553.14 CBK25450.2 - 5.1e-40 137.6 16.8 5.1e-40 137.6 16.8 2.2 2 0 0 2 2 2 1 Na+/H+ antiporter family CitMHS PF03600.16 CBK25450.2 - 5.2e-05 22.6 37.6 0.0003 20.1 24.3 2.4 1 1 1 2 2 2 2 Citrate transporter tRNA-synt_1g PF09334.11 CBK25451.2 - 1.9e-147 491.1 0.0 2.6e-147 490.7 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 CBK25451.2 - 7.4e-09 34.4 0.6 0.00034 19.0 0.0 3.2 2 1 1 3 3 3 2 tRNA synthetases class I (I, L, M and V) DZR PF12773.7 CBK25451.2 - 0.044 13.8 6.0 0.23 11.5 6.0 2.3 1 1 0 1 1 1 0 Double zinc ribbon zinc_ribbon_9 PF14369.6 CBK25451.2 - 0.92 9.8 4.9 0.25 11.6 1.1 2.1 2 0 0 2 2 2 0 zinc-ribbon RecR PF02132.15 CBK25451.2 - 2.9 7.5 5.0 6 6.5 0.6 2.7 2 0 0 2 2 2 0 RecR protein Cnd1 PF12717.7 CBK25452.2 - 4.8e-40 137.2 0.0 6.7e-40 136.8 0.0 1.2 1 0 0 1 1 1 1 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 CBK25452.2 - 2.7e-06 26.2 0.1 2.9e-06 26.1 0.1 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Nipped-B_C PF12830.7 CBK25452.2 - 0.00042 20.3 0.1 0.00079 19.4 0.1 1.4 1 1 0 1 1 1 1 Sister chromatid cohesion C-terminus HEAT_EZ PF13513.6 CBK25452.2 - 0.2 12.2 0.0 32 5.2 0.0 3.1 3 0 0 3 3 3 0 HEAT-like repeat RRM_1 PF00076.22 CBK25453.2 - 2.3e-27 94.6 0.0 4e-12 45.8 0.0 4.1 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 CBK25453.2 - 7e-08 32.1 1.1 0.04 13.5 0.0 3.1 1 1 2 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 CBK25453.2 - 6.9e-06 25.8 0.1 1.7 8.6 0.1 4.0 3 1 0 3 3 3 3 Occluded RNA-recognition motif Limkain-b1 PF11608.8 CBK25453.2 - 1.6e-05 24.9 0.1 0.49 10.5 0.0 3.4 3 0 0 3 3 3 2 Limkain b1 Nup35_RRM_2 PF14605.6 CBK25453.2 - 2.7e-05 24.1 0.1 0.052 13.5 0.0 3.6 3 1 0 3 3 3 1 Nup53/35/40-type RNA recognition motif Nup35_RRM PF05172.13 CBK25453.2 - 0.0001 22.2 0.6 1.3 9.0 0.0 3.7 3 1 0 3 3 3 2 Nup53/35/40-type RNA recognition motif RRM_7 PF16367.5 CBK25453.2 - 0.0079 16.3 0.1 0.078 13.1 0.0 2.4 2 1 0 2 2 2 1 RNA recognition motif DUF4523 PF15023.6 CBK25453.2 - 0.078 12.8 0.2 0.83 9.5 0.1 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF4523) Ribosomal_L5_C PF00673.21 CBK25454.2 - 1.6e-20 73.0 0.0 2.5e-20 72.4 0.0 1.3 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.19 CBK25454.2 - 6e-19 68.1 0.3 1.2e-18 67.2 0.1 1.6 2 0 0 2 2 2 1 Ribosomal protein L5 HTH_ABP1_N PF18107.1 CBK25454.2 - 0.021 14.5 0.3 0.071 12.8 0.1 1.8 2 0 0 2 2 2 0 Fission yeast centromere protein N-terminal domain AP_endonuc_2 PF01261.24 CBK25455.2 - 2.2e-06 27.3 0.0 8.3e-06 25.4 0.0 1.8 1 1 1 2 2 2 1 Xylose isomerase-like TIM barrel Utp12 PF04003.12 CBK25456.2 - 1.3e-16 60.8 3.0 2.2e-16 60.1 3.0 1.4 1 0 0 1 1 1 1 Dip2/Utp12 Family CDC45 PF02724.14 CBK25457.2 - 0.09 11.1 15.0 0.13 10.5 15.0 1.2 1 0 0 1 1 1 0 CDC45-like protein RR_TM4-6 PF06459.12 CBK25457.2 - 0.13 12.1 10.6 0.19 11.5 10.6 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF1387 PF07139.11 CBK25457.2 - 0.22 11.2 12.1 0.29 10.8 12.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) DUF3801 PF12687.7 CBK25457.2 - 0.36 10.9 20.3 0.91 9.6 20.2 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3801) Presenilin PF01080.17 CBK25457.2 - 0.56 8.9 16.8 0.8 8.4 16.8 1.3 1 0 0 1 1 1 0 Presenilin SpoIIP PF07454.11 CBK25457.2 - 0.87 9.0 13.8 1.7 8.0 13.8 1.5 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) FAM60A PF15396.6 CBK25457.2 - 1.4 8.9 7.2 2.1 8.3 7.2 1.5 1 0 0 1 1 1 0 Protein Family FAM60A CobT PF06213.12 CBK25457.2 - 1.8 7.9 26.7 3.8 6.8 26.7 1.6 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT DUF908 PF06012.12 CBK25457.2 - 1.8 7.9 13.5 2.8 7.2 13.5 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) Membralin PF09746.9 CBK25457.2 - 3.2 6.7 7.1 3.9 6.4 7.1 1.1 1 0 0 1 1 1 0 Tumour-associated protein ALMT PF11744.8 CBK25457.2 - 3.3 6.5 8.4 4.5 6.0 8.4 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter Connexin PF00029.19 CBK25457.2 - 4.4 7.0 6.6 6.5 6.4 6.6 1.3 1 0 0 1 1 1 0 Connexin CLN3 PF02487.17 CBK25457.2 - 7.3 5.5 7.8 9.1 5.2 7.8 1.3 1 0 0 1 1 1 0 CLN3 protein Hid1 PF12722.7 CBK25457.2 - 8.6 4.3 15.1 10 4.1 15.1 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein CAML PF14963.6 CBK25457.2 - 9.2 6.3 9.1 15 5.6 9.1 1.2 1 0 0 1 1 1 0 Calcium signal-modulating cyclophilin ligand Gti1_Pac2 PF09729.9 CBK25457.2 - 9.8 6.2 17.5 1.7 8.7 13.9 1.6 2 0 0 2 2 2 0 Gti1/Pac2 family SLC12 PF03522.15 CBK25457.2 - 9.8 5.1 17.7 14 4.5 17.7 1.2 1 0 0 1 1 1 0 Solute carrier family 12 Cob_adeno_trans PF01923.18 CBK25458.2 - 1.8e-52 177.8 0.0 2.1e-52 177.5 0.0 1.1 1 0 0 1 1 1 1 Cobalamin adenosyltransferase DUF4389 PF14333.6 CBK25458.2 - 0.1 12.5 0.0 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4389) ATP-grasp_5 PF13549.6 CBK25459.2 - 1.5e-52 178.3 0.0 2.2e-52 177.7 0.0 1.2 1 0 0 1 1 1 1 ATP-grasp domain Succ_CoA_lig PF13607.6 CBK25459.2 - 2.9e-40 137.3 0.0 1.5e-39 135.0 0.0 2.2 2 0 0 2 2 2 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.6 CBK25459.2 - 2e-18 67.0 0.0 5.9e-18 65.5 0.0 1.9 2 0 0 2 2 2 1 CoA binding domain CoA_binding PF02629.19 CBK25459.2 - 2.7e-05 24.8 0.0 6.5e-05 23.5 0.0 1.7 1 0 0 1 1 1 1 CoA binding domain tRNA_bind PF01588.20 CBK25460.2 - 3.1e-18 65.7 0.0 4.4e-18 65.2 0.0 1.2 1 0 0 1 1 1 1 Putative tRNA binding domain Glyco_transf_49 PF13896.6 CBK25460.2 - 1.6e-08 34.3 0.0 2e-08 34.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyl-transferase for dystroglycan MatE PF01554.18 CBK25461.2 - 3e-26 92.0 23.8 1.4e-16 60.6 2.5 3.8 4 0 0 4 4 4 2 MatE Polysacc_synt_C PF14667.6 CBK25461.2 - 0.0011 19.0 11.1 0.0011 19.0 11.1 4.3 2 1 2 4 4 4 2 Polysaccharide biosynthesis C-terminal domain Pkinase PF00069.25 CBK25462.2 - 0.00018 21.0 0.4 0.00084 18.8 0.3 1.9 1 1 0 1 1 1 1 Protein kinase domain Viral_P18 PF04521.13 CBK25462.2 - 0.1 12.4 0.1 0.43 10.4 0.0 2.0 3 0 0 3 3 3 0 ssRNA positive strand viral 18kD cysteine rich protein PPIP5K2_N PF18086.1 CBK25463.2 - 2.1e-32 111.1 0.1 2.5e-32 110.9 0.1 1.1 1 0 0 1 1 1 1 Diphosphoinositol pentakisphosphate kinase 2 N-terminal domain His_Phos_2 PF00328.22 CBK25464.2 - 2.8e-68 231.0 1.6 4e-68 230.5 1.6 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) RimK PF08443.11 CBK25464.2 - 0.00021 20.9 0.0 0.0004 20.0 0.0 1.4 1 0 0 1 1 1 1 RimK-like ATP-grasp domain BCNT PF07572.12 CBK25465.2 - 5.1e-22 77.7 8.6 5.1e-22 77.7 8.6 2.4 3 0 0 3 3 3 1 Bucentaur or craniofacial development baeRF_family3 PF18845.1 CBK25465.2 - 0.1 12.9 0.1 0.1 12.9 0.1 2.7 2 1 1 3 3 3 0 Bacterial archaeo-eukaryotic release factor family 3 Glyco_hydro_47 PF01532.20 CBK25466.2 - 6.2e-116 388.0 1.9 8.9e-116 387.5 1.9 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 RRM_1 PF00076.22 CBK25467.2 - 7e-13 48.2 0.0 1e-12 47.7 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Bac_rhamnosid_N PF08531.10 CBK25467.2 - 0.27 11.0 0.6 0.45 10.3 0.6 1.3 1 0 0 1 1 1 0 Alpha-L-rhamnosidase N-terminal domain WAK PF08488.11 CBK25468.2 - 0.066 13.7 0.1 0.076 13.5 0.1 1.1 1 0 0 1 1 1 0 Wall-associated kinase PTEN_C2 PF10409.9 CBK25469.2 - 7.8e-07 28.9 0.0 1.5e-06 28.0 0.0 1.5 1 0 0 1 1 1 1 C2 domain of PTEN tumour-suppressor protein Y_phosphatase PF00102.27 CBK25469.2 - 0.0021 17.7 0.1 0.0043 16.7 0.1 1.5 1 1 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 CBK25469.2 - 0.0031 17.5 0.1 0.014 15.4 0.0 2.1 2 0 0 2 2 2 1 Tyrosine phosphatase family DSPc PF00782.20 CBK25469.2 - 0.031 14.1 0.2 0.078 12.8 0.2 1.6 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain Y_phosphatase2 PF03162.13 CBK25469.2 - 0.035 13.7 0.1 0.071 12.7 0.1 1.5 1 0 0 1 1 1 0 Tyrosine phosphatase family PTPlike_phytase PF14566.6 CBK25469.2 - 0.072 13.2 0.0 0.2 11.7 0.0 1.8 1 0 0 1 1 1 0 Inositol hexakisphosphate CDKN3 PF05706.12 CBK25469.2 - 0.1 12.2 0.2 0.22 11.2 0.2 1.6 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) AMP-binding PF00501.28 CBK25470.2 - 6.1e-15 54.7 0.1 1.6e-13 50.1 0.1 2.2 1 1 0 1 1 1 1 AMP-binding enzyme Mito_carr PF00153.27 CBK25471.2 - 9.1e-47 156.9 0.5 2.2e-17 62.7 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Methyltransf_11 PF08241.12 CBK25472.2 - 6.2e-16 58.8 0.0 1e-15 58.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CBK25472.2 - 2.3e-15 57.1 0.0 3.9e-15 56.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CBK25472.2 - 3.6e-11 43.1 0.0 4.8e-11 42.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 CBK25472.2 - 5.8e-10 39.2 0.0 8.3e-10 38.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CBK25472.2 - 9.1e-09 36.0 0.0 1.4e-08 35.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 CBK25472.2 - 1.8e-05 24.2 0.0 2.3e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Ubie_methyltran PF01209.18 CBK25472.2 - 2.5e-05 23.7 0.0 3.7e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_9 PF08003.11 CBK25472.2 - 0.00011 21.3 0.1 0.00026 20.0 0.1 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_8 PF05148.15 CBK25472.2 - 0.00032 20.6 0.0 0.00043 20.2 0.0 1.2 1 0 0 1 1 1 1 Hypothetical methyltransferase MetW PF07021.12 CBK25472.2 - 0.00047 19.8 0.0 0.00071 19.2 0.0 1.2 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW MTS PF05175.14 CBK25472.2 - 0.00089 18.8 0.0 0.0015 18.1 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase small domain TehB PF03848.14 CBK25472.2 - 0.088 12.2 0.1 0.34 10.3 0.1 1.8 1 1 0 1 1 1 0 Tellurite resistance protein TehB DUF726 PF05277.12 CBK25473.2 - 9.6e-35 120.1 0.1 1.1e-34 120.0 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF726) LIDHydrolase PF10230.9 CBK25473.2 - 0.0085 15.7 0.0 0.011 15.3 0.0 1.4 1 1 0 1 1 1 1 Lipid-droplet associated hydrolase PFK PF00365.20 CBK25474.2 - 4.8e-27 95.0 0.0 4.3e-26 91.9 0.0 2.1 1 1 0 1 1 1 1 Phosphofructokinase RsgA_N PF16745.5 CBK25474.2 - 0.037 13.8 0.1 5.9 6.7 0.0 2.5 2 0 0 2 2 2 0 RsgA N-terminal domain TCR PF03638.15 CBK25475.2 - 5.4e-22 77.8 54.0 3.9e-12 46.2 16.2 2.1 2 0 0 2 2 2 2 Tesmin/TSO1-like CXC domain, cysteine-rich domain XPA_C PF05181.12 CBK25475.2 - 0.33 10.9 3.8 0.66 10.0 0.2 2.4 2 0 0 2 2 2 0 XPA protein C-terminus MSL2-CXC PF16682.5 CBK25475.2 - 8.5 6.6 50.7 7.5 6.8 15.8 2.9 2 2 1 3 3 3 0 CXC domain of E3 ubiquitin-protein ligase MSL2 IP_trans PF02121.18 CBK25476.2 - 2.2e-56 191.2 3.3 2.5e-56 191.0 3.3 1.0 1 0 0 1 1 1 1 Phosphatidylinositol transfer protein HA2 PF04408.23 CBK25477.2 - 5.6e-22 78.1 0.0 5.6e-22 78.1 0.0 2.4 2 1 0 2 2 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 CBK25477.2 - 6.1e-16 58.6 0.0 1.4e-15 57.4 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 CBK25477.2 - 1.9e-14 53.9 0.1 3.2e-13 50.0 0.0 3.0 3 0 0 3 3 3 1 Helicase conserved C-terminal domain S1 PF00575.23 CBK25477.2 - 8.3e-14 51.7 0.2 2e-13 50.4 0.2 1.7 1 0 0 1 1 1 1 S1 RNA binding domain DEAD PF00270.29 CBK25477.2 - 1.6e-07 31.3 0.2 3.6e-07 30.1 0.2 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 CBK25477.2 - 6.9e-07 29.6 0.3 2.5e-06 27.8 0.1 2.0 2 0 0 2 2 1 1 AAA domain T2SSE PF00437.20 CBK25477.2 - 3.9e-05 22.9 0.1 9.2e-05 21.6 0.1 1.7 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_30 PF13604.6 CBK25477.2 - 0.00025 20.8 0.1 0.00054 19.7 0.1 1.5 1 0 0 1 1 1 1 AAA domain Flavi_DEAD PF07652.14 CBK25477.2 - 0.0022 18.0 0.1 0.0045 17.0 0.1 1.5 1 0 0 1 1 1 1 Flavivirus DEAD domain AAA_19 PF13245.6 CBK25477.2 - 0.0028 18.0 0.1 0.0067 16.8 0.1 1.6 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.6 CBK25477.2 - 0.0091 16.0 0.6 0.23 11.5 0.6 2.5 1 1 0 1 1 1 1 AAA domain Apt1 PF10351.9 CBK25477.2 - 0.023 13.6 8.8 0.036 12.9 8.8 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain ABC_tran PF00005.27 CBK25477.2 - 0.026 15.0 0.2 0.51 10.8 0.1 2.8 2 0 0 2 2 2 0 ABC transporter PhoH PF02562.16 CBK25477.2 - 0.032 13.7 0.1 0.11 11.9 0.0 1.9 2 0 0 2 2 2 0 PhoH-like protein ResIII PF04851.15 CBK25477.2 - 0.039 14.0 0.0 6.7 6.7 0.0 2.7 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit ATPase PF06745.13 CBK25477.2 - 0.043 13.2 0.0 0.084 12.2 0.0 1.4 1 0 0 1 1 1 0 KaiC Microtub_bd PF16796.5 CBK25477.2 - 0.069 13.1 0.1 5.9 6.8 0.1 2.7 2 0 0 2 2 2 0 Microtubule binding TrwB_AAD_bind PF10412.9 CBK25477.2 - 0.12 11.2 0.1 0.24 10.3 0.1 1.5 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain AAA_25 PF13481.6 CBK25477.2 - 0.13 11.8 0.0 0.32 10.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 CBK25477.2 - 0.2 11.4 1.0 16 5.2 0.1 2.4 1 1 1 2 2 2 0 IstB-like ATP binding protein Macoilin PF09726.9 CBK25477.2 - 0.26 9.8 7.5 0.42 9.1 7.5 1.3 1 0 0 1 1 1 0 Macoilin family Presenilin PF01080.17 CBK25477.2 - 0.88 8.3 3.6 1.4 7.6 3.6 1.2 1 0 0 1 1 1 0 Presenilin Pkinase PF00069.25 CBK25478.2 - 2.3e-23 82.9 0.0 2.3e-23 82.9 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBK25478.2 - 1.5e-10 40.9 0.0 2.8e-10 39.9 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CBK25478.2 - 2.8e-08 33.0 0.0 2.8e-08 33.0 0.0 2.2 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 CBK25478.2 - 0.00053 20.0 0.0 0.19 11.6 0.0 2.3 2 0 0 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 CBK25478.2 - 0.0041 16.5 0.0 0.0079 15.6 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family CDC45 PF02724.14 CBK25478.2 - 2.2 6.5 26.2 3.2 6.0 26.2 1.1 1 0 0 1 1 1 0 CDC45-like protein Presenilin PF01080.17 CBK25478.2 - 4.8 5.8 18.6 6.6 5.4 18.6 1.1 1 0 0 1 1 1 0 Presenilin Armet PF10208.9 CBK25479.2 - 5.8e-20 71.7 5.8 9.1e-20 71.1 5.8 1.2 1 0 0 1 1 1 1 Degradation arginine-rich protein for mis-folding SAP PF02037.27 CBK25479.2 - 0.022 14.5 0.0 0.05 13.4 0.0 1.7 1 0 0 1 1 1 0 SAP domain HLH PF00010.26 CBK25480.2 - 4e-09 36.3 4.1 4e-09 36.3 4.1 2.3 3 0 0 3 3 3 1 Helix-loop-helix DNA-binding domain UvrD_C PF13361.6 CBK25480.2 - 0.097 12.0 3.4 0.13 11.6 3.4 1.2 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain DSPc PF00782.20 CBK25481.2 - 2.9e-17 62.7 0.3 5e-17 62.0 0.3 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain CDKN3 PF05706.12 CBK25481.2 - 0.0021 17.8 0.5 0.0039 16.9 0.5 1.4 1 0 0 1 1 1 1 Cyclin-dependent kinase inhibitor 3 (CDKN3) Chal_sti_synt_C PF02797.15 CBK25481.2 - 0.0085 16.1 0.0 3.5 7.6 0.0 2.2 2 0 0 2 2 2 2 Chalcone and stilbene synthases, C-terminal domain Collagen_bind PF05737.12 CBK25481.2 - 0.075 13.2 0.1 0.16 12.1 0.0 1.5 2 0 0 2 2 2 0 Collagen binding domain MAM33 PF02330.16 CBK25482.2 - 3.7e-15 56.4 9.5 3.8e-14 53.1 9.5 2.0 1 1 0 1 1 1 1 Mitochondrial glycoprotein Utp21 PF04192.12 CBK25482.2 - 0.024 14.1 0.2 0.69 9.4 0.0 2.2 2 0 0 2 2 2 0 Utp21 specific WD40 associated putative domain CCDC53 PF10152.9 CBK25483.2 - 0.014 15.9 5.0 0.018 15.4 5.0 1.3 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex tRNA-synt_1c PF00749.21 CBK25483.2 - 0.016 14.1 4.2 0.019 13.9 4.2 1.1 1 0 0 1 1 1 0 tRNA synthetases class I (E and Q), catalytic domain DUF45 PF01863.17 CBK25483.2 - 0.12 12.4 4.1 0.17 11.9 4.1 1.3 1 0 0 1 1 1 0 Protein of unknown function DUF45 Spt20 PF12090.8 CBK25483.2 - 0.13 11.9 8.3 0.13 11.8 8.3 1.2 1 0 0 1 1 1 0 Spt20 family NPR3 PF03666.13 CBK25483.2 - 0.17 10.7 7.5 0.16 10.7 7.5 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Hid1 PF12722.7 CBK25483.2 - 0.57 8.2 8.3 0.59 8.2 8.3 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein SspB PF04386.13 CBK25483.2 - 0.63 9.9 5.7 0.85 9.5 5.7 1.4 1 0 0 1 1 1 0 Stringent starvation protein B RR_TM4-6 PF06459.12 CBK25483.2 - 1.1 9.1 11.0 1.2 8.9 11.0 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Pribosyl_synth PF14572.6 CBK25483.2 - 1.2 9.2 3.5 0.94 9.5 0.1 1.9 2 0 0 2 2 2 0 Phosphoribosyl synthetase-associated domain Presenilin PF01080.17 CBK25483.2 - 1.8 7.3 8.4 2 7.1 8.4 1.1 1 0 0 1 1 1 0 Presenilin Neur_chan_memb PF02932.16 CBK25483.2 - 4.2 7.4 5.3 4.7 7.2 5.3 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Peptidase_S49_N PF08496.10 CBK25483.2 - 4.6 7.3 7.9 6.4 6.8 7.9 1.4 1 0 0 1 1 1 0 Peptidase family S49 N-terminal HABP4_PAI-RBP1 PF04774.15 CBK25484.2 - 1.5e-11 45.1 10.3 1.5e-11 45.1 10.3 4.2 3 1 1 4 4 4 1 Hyaluronan / mRNA binding family Myb_DNA-binding PF00249.31 CBK25485.2 - 7.3e-13 48.5 0.3 1.3e-12 47.7 0.0 1.6 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 CBK25485.2 - 1.1e-06 28.8 0.1 2e-06 27.9 0.1 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 CBK25485.2 - 9.6e-05 22.2 0.1 0.00019 21.3 0.1 1.5 1 1 0 1 1 1 1 Myb DNA-binding like Nitrate_red_del PF02613.15 CBK25485.2 - 0.049 13.7 0.0 0.073 13.1 0.0 1.4 1 0 0 1 1 1 0 Nitrate reductase delta subunit Glyco_hydro_9 PF00759.19 CBK25485.2 - 0.069 12.6 0.2 0.085 12.3 0.2 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 9 Lyase_aromatic PF00221.19 CBK25486.2 - 7.7e-179 595.2 0.0 8.8e-179 595.0 0.0 1.0 1 0 0 1 1 1 1 Aromatic amino acid lyase Glycos_transf_2 PF00535.26 CBK25487.2 - 8.7e-29 100.5 0.0 1.1e-28 100.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 CBK25487.2 - 5.2e-06 26.5 0.0 8.4e-06 25.8 0.0 1.5 1 1 0 1 1 1 1 Glycosyltransferase like family 2 HIT PF01230.23 CBK25488.2 - 7.9e-19 68.2 0.0 9.2e-19 68.0 0.0 1.0 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 CBK25488.2 - 0.00038 20.9 0.0 0.00044 20.7 0.0 1.1 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.15 CBK25488.2 - 0.0065 16.3 0.0 0.0074 16.1 0.0 1.1 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 GalP_UDP_tr_C PF02744.17 CBK25488.2 - 0.089 12.5 0.0 0.11 12.3 0.0 1.2 1 0 0 1 1 1 0 Galactose-1-phosphate uridyl transferase, C-terminal domain Metallophos PF00149.28 CBK25489.2 - 3.3e-31 109.4 0.0 4.2e-31 109.0 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase VOMI PF03762.17 CBK25489.2 - 0.13 12.3 0.0 0.22 11.6 0.0 1.3 1 0 0 1 1 1 0 Vitelline membrane outer layer protein I (VOMI) EF-hand_1 PF00036.32 CBK25490.2 - 5.7e-14 50.5 0.3 2.4e-05 23.5 0.1 4.3 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.6 CBK25490.2 - 2e-12 45.9 1.8 0.00016 21.3 0.1 4.4 5 0 0 5 5 5 3 EF-hand domain EF-hand_7 PF13499.6 CBK25490.2 - 1.1e-11 44.9 0.0 2.6e-08 34.2 0.0 2.6 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_8 PF13833.6 CBK25490.2 - 1.3e-09 37.7 0.0 0.051 13.4 0.0 3.5 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.6 CBK25490.2 - 1e-05 24.8 1.0 0.0091 15.5 0.1 3.4 3 0 0 3 3 3 2 EF hand OrfB_Zn_ribbon PF07282.11 CBK25490.2 - 0.013 15.4 0.8 1.3 8.9 0.3 2.4 2 0 0 2 2 2 0 Putative transposase DNA-binding domain TF_Zn_Ribbon PF08271.12 CBK25490.2 - 0.1 12.1 0.9 0.19 11.2 0.9 1.5 1 0 0 1 1 1 0 TFIIB zinc-binding DUF4857 PF16149.5 CBK25490.2 - 0.14 11.4 0.0 0.44 9.8 0.0 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4857) AMP-binding PF00501.28 CBK25491.2 - 2.6e-79 266.8 0.0 3.1e-79 266.5 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme FlaE PF07559.14 CBK25491.2 - 0.12 12.9 0.0 0.34 11.5 0.0 1.8 1 0 0 1 1 1 0 Flagellar basal body protein FlaE AMP-binding PF00501.28 CBK25492.2 - 6e-70 235.9 0.1 7.3e-70 235.7 0.1 1.1 1 0 0 1 1 1 1 AMP-binding enzyme FlaE PF07559.14 CBK25492.2 - 0.16 12.6 0.0 0.3 11.7 0.0 1.4 1 0 0 1 1 1 0 Flagellar basal body protein FlaE Pacs-1 PF10254.9 CBK25493.2 - 1.2e-06 27.8 0.0 3.8e-06 26.1 0.0 1.5 1 1 0 1 1 1 1 PACS-1 cytosolic sorting protein Oxidored-like PF09791.9 CBK25493.2 - 0.17 11.6 1.8 0.2 11.4 0.2 1.9 2 0 0 2 2 2 0 Oxidoreductase-like protein, N-terminal UPF0054 PF02130.17 CBK25494.2 - 2.7e-27 95.1 0.1 3.3e-27 94.8 0.1 1.1 1 0 0 1 1 1 1 Uncharacterized protein family UPF0054 Peptidase_M10 PF00413.24 CBK25494.2 - 0.0042 17.0 0.1 0.011 15.6 0.1 1.7 1 1 0 1 1 1 1 Matrixin Phage_int_SAM_5 PF13102.6 CBK25494.2 - 0.056 13.8 0.5 0.12 12.7 0.5 1.5 1 0 0 1 1 1 0 Phage integrase SAM-like domain DUF4296 PF14129.6 CBK25495.2 - 0.0011 19.5 1.8 0.0011 19.5 1.8 2.6 2 1 0 2 2 2 1 Domain of unknown function (DUF4296) T2SSF PF00482.23 CBK25495.2 - 0.047 13.6 1.7 0.09 12.7 0.9 1.8 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein F DUF5035 PF16438.5 CBK25495.2 - 0.17 11.7 2.6 0.1 12.4 0.4 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF5035) TetR_C_11 PF16859.5 CBK25495.2 - 0.19 12.0 0.1 31 4.9 0.0 2.3 1 1 1 2 2 2 0 Tetracyclin repressor-like, C-terminal domain STI1 PF17830.1 CBK25495.2 - 1.8 8.6 7.5 7.2 6.6 4.8 3.0 2 1 0 2 2 2 0 STI1 domain ABC_tran PF00005.27 CBK25496.2 - 3.8e-54 182.9 0.0 6.8e-26 91.4 0.0 3.3 3 0 0 3 3 3 2 ABC transporter ABC2_membrane_3 PF12698.7 CBK25496.2 - 1.2e-51 175.8 61.9 2.6e-30 105.7 24.1 2.6 2 1 0 2 2 2 2 ABC-2 family transporter protein AAA_21 PF13304.6 CBK25496.2 - 8.4e-18 65.2 0.2 6.9e-07 29.4 0.0 4.3 4 0 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 CBK25496.2 - 2.2e-08 33.8 0.2 0.0062 16.0 0.0 3.1 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 CBK25496.2 - 4.5e-05 24.0 3.7 0.0077 16.8 0.0 3.1 3 0 0 3 3 3 2 AAA domain SbcCD_C PF13558.6 CBK25496.2 - 0.00021 21.5 0.0 0.031 14.5 0.0 3.4 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit RsgA_GTPase PF03193.16 CBK25496.2 - 0.00029 20.8 0.4 0.03 14.2 0.0 3.0 2 1 0 2 2 2 1 RsgA GTPase SRP54 PF00448.22 CBK25496.2 - 0.0013 18.4 1.7 0.72 9.4 0.1 2.4 2 0 0 2 2 2 2 SRP54-type protein, GTPase domain DUF4162 PF13732.6 CBK25496.2 - 0.0021 18.7 0.6 0.27 12.0 0.1 3.5 3 0 0 3 3 3 1 Domain of unknown function (DUF4162) ATP-synt_ab PF00006.25 CBK25496.2 - 0.0062 16.2 0.0 2.8 7.5 0.0 2.3 2 0 0 2 2 2 2 ATP synthase alpha/beta family, nucleotide-binding domain AAA_15 PF13175.6 CBK25496.2 - 0.0063 16.3 0.0 7 6.2 0.1 3.2 2 1 1 3 3 3 2 AAA ATPase domain Ppx-GppA PF02541.16 CBK25496.2 - 0.038 13.4 0.2 0.069 12.6 0.2 1.3 1 0 0 1 1 1 0 Ppx/GppA phosphatase family AAA_24 PF13479.6 CBK25496.2 - 0.044 13.5 0.1 2.7 7.7 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 CBK25496.2 - 0.057 13.2 0.1 3.4 7.5 0.0 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 CBK25496.2 - 0.064 13.3 0.1 6 7.0 0.0 2.7 2 0 0 2 2 2 0 50S ribosome-binding GTPase DUF3669 PF12417.8 CBK25496.2 - 0.15 12.3 0.0 0.53 10.5 0.0 1.9 1 0 0 1 1 1 0 Zinc finger protein AAA PF00004.29 CBK25496.2 - 1.7 9.1 3.7 11 6.4 0.2 3.4 2 2 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) DASH_Duo1 PF08651.10 CBK25498.2 - 0.0088 15.8 0.2 0.0094 15.7 0.2 1.1 1 0 0 1 1 1 1 DASH complex subunit Duo1 DASH_Dad2 PF08654.10 CBK25498.2 - 0.028 14.8 0.6 0.032 14.7 0.6 1.0 1 0 0 1 1 1 0 DASH complex subunit Dad2 MORN PF02493.20 CBK25499.2 - 9.6e-47 154.2 79.1 2.2e-06 27.2 2.4 13.1 13 0 0 13 13 13 12 MORN repeat TPR_12 PF13424.6 CBK25501.2 - 0.01 16.1 0.7 0.01 16.1 0.7 2.4 2 1 0 2 2 2 0 Tetratricopeptide repeat Nop14 PF04147.12 CBK25501.2 - 0.066 11.4 23.9 0.082 11.1 23.9 1.0 1 0 0 1 1 1 0 Nop14-like family Sporozoite_P67 PF05642.11 CBK25501.2 - 0.33 9.0 4.2 0.48 8.5 4.2 1.3 1 0 0 1 1 1 0 Sporozoite P67 surface antigen LRIF1 PF15741.5 CBK25501.2 - 0.71 8.3 7.4 0.84 8.1 7.4 1.1 1 0 0 1 1 1 0 Ligand-dependent nuclear receptor-interacting factor 1 TRAP_alpha PF03896.16 CBK25501.2 - 1.2 8.3 5.5 2.1 7.5 5.5 1.4 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Phage_Gp23 PF10669.9 CBK25501.2 - 3.3 8.1 12.6 8.4 6.8 12.6 1.7 1 0 0 1 1 1 0 Protein gp23 (Bacteriophage A118) Presenilin PF01080.17 CBK25501.2 - 3.4 6.3 7.5 5.7 5.6 7.5 1.3 1 0 0 1 1 1 0 Presenilin TLP-20 PF06088.11 CBK25501.2 - 3.6 7.5 7.9 6.2 6.7 7.9 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) Hanta_G2 PF01561.16 CBK25502.2 - 5.4e-05 22.0 0.4 6.3e-05 21.8 0.4 1.0 1 0 0 1 1 1 1 Hantavirus glycoprotein G2 OAD_gamma PF04277.13 CBK25502.2 - 0.00012 22.6 1.0 0.00018 22.0 1.0 1.2 1 0 0 1 1 1 1 Oxaloacetate decarboxylase, gamma chain DUF4064 PF13273.6 CBK25502.2 - 0.007 16.6 0.1 0.0091 16.3 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4064) Baculo_F PF12259.8 CBK25502.2 - 0.0094 14.5 0.1 0.01 14.4 0.1 1.1 1 0 0 1 1 1 1 Baculovirus F protein Orf78 PF06024.12 CBK25502.2 - 0.043 14.1 0.1 0.067 13.5 0.1 1.3 1 0 0 1 1 1 0 Orf78 (ac78) Sigma_reg_N PF13800.6 CBK25502.2 - 0.056 13.7 0.5 0.096 13.0 0.5 1.4 1 0 0 1 1 1 0 Sigma factor regulator N-terminal DUF4231 PF14015.6 CBK25502.2 - 0.11 13.0 0.0 0.14 12.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4231) Baculo_11_kDa PF06143.11 CBK25502.2 - 0.13 11.9 2.0 0.23 11.1 2.0 1.4 1 0 0 1 1 1 0 Baculovirus 11 kDa family EphA2_TM PF14575.6 CBK25502.2 - 0.19 12.6 0.6 0.6 11.0 0.7 1.7 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Pkinase_Tyr PF07714.17 CBK25503.2 - 2.8e-67 226.7 0.0 3.2e-67 226.5 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 CBK25503.2 - 1e-55 189.0 0.0 1.3e-55 188.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 CBK25503.2 - 0.0011 17.9 0.0 0.0018 17.1 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 CBK25503.2 - 0.072 12.0 0.0 0.11 11.4 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain ANTH PF07651.16 CBK25504.2 - 7.1e-09 35.1 0.2 1.4e-08 34.1 0.2 1.4 1 0 0 1 1 1 1 ANTH domain Pkinase_Tyr PF07714.17 CBK25504.2 - 0.00075 18.9 0.0 0.0015 17.9 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase zf-H2C2_2 PF13465.6 CBK25505.2 - 4.5e-17 61.6 26.2 2.1e-06 27.9 0.6 5.5 5 0 0 5 5 5 4 Zinc-finger double domain zf-C2H2 PF00096.26 CBK25505.2 - 0.0004 20.7 34.8 0.034 14.6 0.8 6.1 5 2 0 5 5 5 3 Zinc finger, C2H2 type zf-H2C2_5 PF13909.6 CBK25505.2 - 0.0022 17.7 0.7 0.0022 17.7 0.7 4.2 4 1 0 4 4 4 2 C2H2-type zinc-finger domain zf-C2H2_4 PF13894.6 CBK25505.2 - 0.0032 18.2 0.8 0.0032 18.2 0.8 5.7 5 1 0 5 5 5 2 C2H2-type zinc finger OrsD PF12013.8 CBK25505.2 - 0.41 11.1 20.2 3 8.3 1.6 4.9 2 2 3 5 5 5 0 Orsellinic acid/F9775 biosynthesis cluster protein D FOXP-CC PF16159.5 CBK25505.2 - 9.2 7.0 10.2 22 5.8 0.1 4.2 2 2 3 5 5 5 0 FOXP coiled-coil domain Peptidase_C1 PF00112.23 CBK25506.2 - 1.1e-63 215.2 7.4 1.4e-63 214.9 7.4 1.1 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.15 CBK25506.2 - 2.9e-05 23.0 1.7 0.00038 19.3 0.4 2.2 2 0 0 2 2 2 2 Peptidase C1-like family Peptidase_C1 PF00112.23 CBK25507.2 - 1.7e-60 204.8 6.2 2.1e-60 204.5 6.2 1.1 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.15 CBK25507.2 - 6.9e-06 25.1 1.3 0.00013 20.9 0.3 2.3 2 0 0 2 2 2 2 Peptidase C1-like family AI-2E_transport PF01594.16 CBK25508.2 - 4.3e-12 45.8 8.4 6.7e-12 45.2 8.4 1.2 1 0 0 1 1 1 1 AI-2E family transporter E1-E2_ATPase PF00122.20 CBK25508.2 - 0.72 9.3 0.0 0.72 9.3 0.0 2.2 1 1 0 2 2 2 0 E1-E2 ATPase Sec23_trunk PF04811.15 CBK25509.2 - 1.2e-30 106.8 0.0 1.8e-30 106.3 0.0 1.2 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.15 CBK25509.2 - 2.5e-15 56.1 0.1 5.7e-15 55.0 0.1 1.7 1 0 0 1 1 1 1 Sec23/Sec24 helical domain zf-Sec23_Sec24 PF04810.15 CBK25509.2 - 4.7e-14 52.2 1.0 9.4e-14 51.2 1.0 1.6 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Sec23_BS PF08033.12 CBK25509.2 - 6.4e-09 36.4 0.0 2.6e-08 34.5 0.0 2.0 2 0 0 2 2 2 1 Sec23/Sec24 beta-sandwich domain MFS_1 PF07690.16 CBK25510.2 - 2.6e-23 82.5 55.7 1e-20 74.0 23.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Med11 PF10280.9 CBK25511.2 - 0.013 15.9 0.1 0.015 15.8 0.1 1.1 1 0 0 1 1 1 0 Mediator complex protein PHP PF02811.19 CBK25514.2 - 1.7e-07 31.7 0.1 1.8e-07 31.6 0.1 1.2 1 0 0 1 1 1 1 PHP domain Tyr_Deacylase PF02580.16 CBK25515.2 - 2.1e-49 167.8 0.0 2.7e-49 167.4 0.0 1.1 1 0 0 1 1 1 1 D-Tyr-tRNA(Tyr) deacylase ACT_5 PF13710.6 CBK25515.2 - 0.047 13.5 0.2 0.11 12.4 0.0 1.7 2 0 0 2 2 2 0 ACT domain RhoGAP-FF1 PF16512.5 CBK25515.2 - 0.052 14.2 0.2 0.16 12.7 0.2 1.8 1 1 0 1 1 1 0 p190-A and -B Rho GAPs FF domain Ribosomal_S7e PF01251.18 CBK25516.2 - 3.5e-65 219.2 1.0 3.9e-65 219.0 1.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S7e DUF2040 PF09745.9 CBK25517.2 - 4.8e-22 78.3 24.7 4.8e-22 78.3 24.7 2.0 1 1 1 2 2 2 1 Coiled-coil domain-containing protein 55 (DUF2040) TFIIA_gamma_N PF02268.16 CBK25518.2 - 2e-10 40.5 0.1 3.1e-10 39.9 0.1 1.3 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit, helical domain Peptidase_M20 PF01546.28 CBK25519.2 - 1.2e-18 67.6 0.0 1.9e-18 67.0 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 CBK25519.2 - 0.0035 17.3 0.0 0.0069 16.3 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain A2L_zn_ribbon PF08792.10 CBK25519.2 - 1.5 8.6 3.5 0.69 9.7 0.5 2.1 2 0 0 2 2 2 0 A2L zinc ribbon domain Glyco_transf_22 PF03901.17 CBK25520.2 - 6.8e-74 249.6 30.1 8e-74 249.3 30.1 1.0 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family NGP1NT PF08153.12 CBK25521.2 - 1e-45 155.1 0.4 3.5e-45 153.3 0.4 2.0 1 0 0 1 1 1 1 NGP1NT (NUC091) domain MMR_HSR1 PF01926.23 CBK25521.2 - 4.2e-19 68.7 0.4 3.3e-15 56.2 0.0 3.0 2 1 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.18 CBK25521.2 - 2.3e-06 27.2 0.2 1.8e-05 24.3 0.0 2.4 3 0 0 3 3 3 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 CBK25521.2 - 1.2e-05 25.2 0.0 4.6e-05 23.4 0.0 1.9 1 1 0 1 1 1 1 RsgA GTPase Arf PF00025.21 CBK25521.2 - 0.0041 16.6 0.6 0.23 10.9 0.0 2.6 2 1 0 2 2 2 1 ADP-ribosylation factor family Roc PF08477.13 CBK25521.2 - 0.0096 16.1 0.1 5.5 7.2 0.0 2.6 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase cobW PF02492.19 CBK25521.2 - 0.052 13.1 0.0 0.38 10.3 0.0 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Dynamin_N PF00350.23 CBK25521.2 - 2.4 8.2 10.8 8.2 6.5 4.6 4.1 2 2 0 2 2 2 0 Dynamin family Ribosomal_L36e PF01158.18 CBK25522.2 - 1.5e-27 95.7 7.7 1.6e-27 95.5 7.7 1.0 1 0 0 1 1 1 1 Ribosomal protein L36e D5_N PF08706.11 CBK25522.2 - 0.055 13.7 2.1 0.062 13.6 2.1 1.1 1 0 0 1 1 1 0 D5 N terminal like Dak2 PF02734.17 CBK25522.2 - 0.059 13.3 0.1 0.066 13.1 0.1 1.1 1 0 0 1 1 1 0 DAK2 domain DUF2207 PF09972.9 CBK25523.2 - 0.65 8.7 4.4 0.48 9.1 2.6 1.6 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) CitMHS PF03600.16 CBK25523.2 - 3.4 6.8 10.4 6.1 6.0 10.0 1.4 1 1 0 1 1 1 0 Citrate transporter DUF2721 PF11026.8 CBK25523.2 - 4.1 7.3 13.6 4.6 7.1 0.3 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF2721) SF3A2 PF16835.5 CBK25525.2 - 2.7e-34 117.4 0.0 4.5e-34 116.7 0.0 1.4 1 0 0 1 1 1 1 Pre-mRNA-splicing factor SF3a complex subunit 2 (Prp11) zf-met PF12874.7 CBK25525.2 - 4.2e-06 27.0 0.5 8.3e-06 26.0 0.5 1.5 1 0 0 1 1 1 1 Zinc-finger of C2H2 type CactinC_cactus PF09732.9 CBK25525.2 - 1.3e-05 25.1 0.2 2.2e-05 24.4 0.2 1.3 1 0 0 1 1 1 1 Cactus-binding C-terminus of cactin protein GATase_5 PF13507.6 CBK25525.2 - 0.052 12.6 0.0 0.15 11.1 0.0 1.7 2 0 0 2 2 2 0 CobB/CobQ-like glutamine amidotransferase domain DUF4957 PF16318.5 CBK25526.2 - 0.062 13.2 3.4 0.22 11.4 3.4 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4957) Band_7 PF01145.25 CBK25527.2 - 3.5e-23 82.5 2.8 4.5e-23 82.2 1.2 1.8 1 1 1 2 2 2 1 SPFH domain / Band 7 family YdfA_immunity PF12127.8 CBK25527.2 - 7.7e-05 21.9 6.7 0.0001 21.5 6.7 1.1 1 0 0 1 1 1 1 SigmaW regulon antibacterial Band_7_1 PF13421.6 CBK25527.2 - 0.087 12.5 0.2 0.14 11.9 0.2 1.4 1 0 0 1 1 1 0 SPFH domain-Band 7 family YpjP PF14005.6 CBK25527.2 - 0.12 12.4 0.4 0.39 10.8 0.1 1.9 1 1 0 2 2 2 0 YpjP-like protein ZnuA PF01297.17 CBK25527.2 - 0.17 11.3 3.5 0.23 10.8 3.5 1.1 1 0 0 1 1 1 0 Zinc-uptake complex component A periplasmic Pre-PUA PF17832.1 CBK25528.2 - 2.9e-23 82.3 0.1 4.2e-23 81.8 0.1 1.2 1 0 0 1 1 1 1 Pre-PUA-like domain PUA PF01472.20 CBK25528.2 - 4.3e-18 65.0 0.1 8.9e-18 64.0 0.1 1.6 1 0 0 1 1 1 1 PUA domain DUF4292 PF14125.6 CBK25528.2 - 0.0054 16.4 0.1 0.007 16.1 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4292) Mito_carr PF00153.27 CBK25529.2 - 2.5e-53 178.0 1.4 6.8e-17 61.2 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF1500 PF07389.12 CBK25529.2 - 0.033 14.3 0.0 0.072 13.2 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1500) DUF3147 PF11345.8 CBK25530.2 - 5.4e-08 33.2 24.2 0.00034 21.0 4.9 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF3147) Lin-8 PF03353.15 CBK25530.2 - 0.055 13.0 0.4 0.076 12.6 0.4 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist ThrE PF06738.12 CBK25530.2 - 1.9 7.8 15.5 0.065 12.6 7.8 2.3 1 1 0 2 2 2 0 Putative threonine/serine exporter DUF4131 PF13567.6 CBK25530.2 - 4.4 6.9 11.5 10 5.7 0.3 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF4131) ArfGap PF01412.18 CBK25531.2 - 9.4e-46 154.7 1.0 1.4e-45 154.2 1.0 1.2 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf ABC_tran PF00005.27 CBK25532.2 - 8.6e-34 117.0 0.0 1.6e-15 57.9 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 CBK25532.2 - 1.9e-13 50.4 1.8 0.0011 18.4 0.0 4.1 3 1 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 CBK25532.2 - 2.3e-13 50.6 1.8 0.0041 17.0 0.0 4.2 2 2 1 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system RLI PF04068.15 CBK25532.2 - 1.3e-11 44.1 3.4 1.3e-11 44.1 3.4 1.9 2 0 0 2 2 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI Fer4 PF00037.27 CBK25532.2 - 4e-08 32.7 3.0 4e-08 32.7 3.0 2.2 2 0 0 2 2 1 1 4Fe-4S binding domain AAA_15 PF13175.6 CBK25532.2 - 1.6e-06 28.1 0.1 0.15 11.7 0.0 3.4 3 0 0 3 3 3 2 AAA ATPase domain AAA_16 PF13191.6 CBK25532.2 - 5.9e-06 26.8 0.0 0.083 13.3 0.0 2.6 2 1 0 2 2 2 2 AAA ATPase domain Fer4_6 PF12837.7 CBK25532.2 - 8.3e-06 25.7 2.0 8.3e-06 25.7 2.0 2.4 2 0 0 2 2 2 1 4Fe-4S binding domain AAA PF00004.29 CBK25532.2 - 5.7e-05 23.6 0.0 0.33 11.4 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 CBK25532.2 - 5.8e-05 23.1 0.1 0.022 14.7 0.1 3.2 2 1 1 3 3 3 1 Rad17 P-loop domain RsgA_GTPase PF03193.16 CBK25532.2 - 8e-05 22.6 0.1 0.42 10.5 0.0 2.9 2 0 0 2 2 2 2 RsgA GTPase NACHT PF05729.12 CBK25532.2 - 0.00011 22.2 0.5 0.051 13.5 0.0 2.6 3 0 0 3 3 2 1 NACHT domain SRP54 PF00448.22 CBK25532.2 - 0.00015 21.5 1.4 0.045 13.4 0.0 2.2 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_22 PF13401.6 CBK25532.2 - 0.00021 21.6 0.0 0.11 12.7 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 CBK25532.2 - 0.00027 20.6 0.2 0.64 9.8 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.6 CBK25532.2 - 0.00032 21.3 0.1 0.075 13.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain Fer4_7 PF12838.7 CBK25532.2 - 0.00034 21.2 1.1 0.00034 21.2 1.1 2.3 1 1 2 3 3 2 2 4Fe-4S dicluster domain Fer4_2 PF12797.7 CBK25532.2 - 0.00059 19.8 0.7 0.00059 19.8 0.7 2.4 2 0 0 2 2 2 1 4Fe-4S binding domain AAA_24 PF13479.6 CBK25532.2 - 0.0012 18.6 0.7 0.41 10.3 0.0 2.6 2 1 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 CBK25532.2 - 0.0018 18.6 0.0 3.2 8.2 0.0 2.8 2 0 0 2 2 2 1 RNA helicase AAA_30 PF13604.6 CBK25532.2 - 0.0019 18.0 0.1 0.38 10.4 0.0 2.6 2 0 0 2 2 2 1 AAA domain Fer4_10 PF13237.6 CBK25532.2 - 0.0027 17.8 1.4 0.0027 17.8 1.4 2.4 1 1 1 2 2 2 2 4Fe-4S dicluster domain AAA_33 PF13671.6 CBK25532.2 - 0.0028 17.8 0.0 1.6 8.9 0.0 2.6 2 0 0 2 2 2 1 AAA domain TsaE PF02367.17 CBK25532.2 - 0.0031 17.5 0.0 0.13 12.3 0.0 2.4 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE SbcCD_C PF13558.6 CBK25532.2 - 0.004 17.4 0.0 0.52 10.6 0.0 2.9 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit Fer4_16 PF13484.6 CBK25532.2 - 0.0049 17.8 0.3 0.0049 17.8 0.3 2.3 2 0 0 2 2 1 1 4Fe-4S double cluster binding domain Fer4_9 PF13187.6 CBK25532.2 - 0.005 17.0 10.7 0.0094 16.1 10.7 1.5 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_21 PF14697.6 CBK25532.2 - 0.0083 16.2 11.1 0.022 14.9 11.1 1.7 1 1 0 1 1 1 1 4Fe-4S dicluster domain Thymidylate_kin PF02223.17 CBK25532.2 - 0.013 15.2 0.1 2.1 8.0 0.0 2.5 2 0 0 2 2 2 0 Thymidylate kinase AAA_5 PF07728.14 CBK25532.2 - 0.015 15.3 0.6 1.2 9.1 0.0 2.9 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) AAA_28 PF13521.6 CBK25532.2 - 0.021 15.1 1.7 2.4 8.4 0.0 2.8 3 0 0 3 3 2 0 AAA domain DUF815 PF05673.13 CBK25532.2 - 0.028 13.6 0.1 2.3 7.3 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_18 PF13238.6 CBK25532.2 - 0.032 14.8 0.0 7.7 7.1 0.0 2.5 2 0 0 2 2 2 0 AAA domain VirE PF05272.11 CBK25532.2 - 0.041 13.6 0.0 5.4 6.7 0.0 2.3 2 0 0 2 2 2 0 Virulence-associated protein E AAA_7 PF12775.7 CBK25532.2 - 0.047 13.2 0.1 1.2 8.6 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_13 PF13166.6 CBK25532.2 - 0.11 11.1 0.5 0.22 10.1 0.0 1.7 2 0 0 2 2 1 0 AAA domain AAA_14 PF13173.6 CBK25532.2 - 0.12 12.4 0.0 12 5.9 0.0 2.9 3 0 0 3 3 2 0 AAA domain AAA_19 PF13245.6 CBK25532.2 - 0.12 12.7 0.3 1.5 9.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 CBK25532.2 - 0.13 12.3 1.3 14 5.8 0.0 2.9 3 0 0 3 3 2 0 50S ribosome-binding GTPase Fer4_8 PF13183.6 CBK25532.2 - 0.14 12.7 0.2 0.14 12.7 0.2 2.2 2 0 0 2 2 1 0 4Fe-4S dicluster domain DUF359 PF04019.12 CBK25532.2 - 0.14 11.8 0.1 0.44 10.2 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF359) KAP_NTPase PF07693.14 CBK25532.2 - 0.14 11.4 0.0 4.2 6.5 0.0 2.2 2 0 0 2 2 2 0 KAP family P-loop domain NB-ARC PF00931.22 CBK25532.2 - 0.15 11.3 0.0 9.6 5.3 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain NTPase_1 PF03266.15 CBK25532.2 - 1.1 9.1 4.9 8.1 6.3 0.0 3.2 4 0 0 4 4 3 0 NTPase Fer4_4 PF12800.7 CBK25532.2 - 3.8 8.3 15.1 0.14 12.7 3.2 2.5 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_3 PF12798.7 CBK25532.2 - 7.4 7.8 14.2 0.085 13.8 4.2 2.5 2 1 0 2 2 1 0 4Fe-4S binding domain Carboxyl_trans PF01039.22 CBK25534.2 - 4.3e-132 441.2 0.0 5.7e-132 440.8 0.0 1.1 1 0 0 1 1 1 1 Carboxyl transferase domain Aa_trans PF01490.18 CBK25535.2 - 7.3e-27 94.1 19.3 9.7e-27 93.7 19.3 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Spindle_Spc25 PF08234.12 CBK25536.2 - 2.5e-18 66.1 0.9 2.5e-18 66.1 0.9 2.1 2 1 0 2 2 2 1 Chromosome segregation protein Spc25 DUF4407 PF14362.6 CBK25536.2 - 0.0064 15.9 9.3 0.0088 15.4 9.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4407) ATG16 PF08614.11 CBK25536.2 - 0.024 14.8 10.1 0.024 14.8 10.1 2.1 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) DUF948 PF06103.11 CBK25536.2 - 0.47 10.7 2.0 3.4 8.0 1.2 2.3 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) V_ATPase_I PF01496.19 CBK25536.2 - 0.54 8.1 5.8 0.53 8.1 5.8 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Exonuc_VII_L PF02601.15 CBK25536.2 - 0.74 9.3 5.9 0.97 8.9 5.9 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit Atg14 PF10186.9 CBK25536.2 - 0.79 8.7 15.6 1.3 8.1 15.6 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 UPF0242 PF06785.11 CBK25536.2 - 1.2 9.2 16.9 2.5 8.2 16.9 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus FapA PF03961.13 CBK25536.2 - 1.6 7.3 14.5 2.1 6.9 14.5 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A TMPIT PF07851.13 CBK25536.2 - 5.8 6.1 7.6 8.1 5.6 7.6 1.4 1 0 0 1 1 1 0 TMPIT-like protein TRAP_beta PF05753.14 CBK25537.2 - 6e-14 51.8 0.0 7.1e-14 51.6 0.0 1.0 1 0 0 1 1 1 1 Translocon-associated protein beta (TRAPB) EAF PF09816.9 CBK25539.2 - 0.026 14.9 0.0 0.031 14.7 0.0 1.2 1 0 0 1 1 1 0 RNA polymerase II transcription elongation factor Pkinase PF00069.25 CBK25540.2 - 6.9e-41 140.4 0.3 1.1e-40 139.7 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBK25540.2 - 2.1e-22 79.7 0.0 3.1e-22 79.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.11 CBK25540.2 - 0.0028 16.7 1.8 0.0034 16.4 0.5 1.9 1 1 1 2 2 2 1 Poxvirus serine/threonine protein kinase APH PF01636.23 CBK25540.2 - 0.017 15.0 0.0 0.026 14.4 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kinase-like PF14531.6 CBK25540.2 - 0.054 12.8 0.0 0.29 10.4 0.0 2.1 1 1 1 2 2 2 0 Kinase-like DUF349 PF03993.12 CBK25540.2 - 0.11 12.8 5.0 0.41 11.0 3.5 2.2 2 0 0 2 2 2 0 Domain of Unknown Function (DUF349) WD40 PF00400.32 CBK25541.2 - 5.1e-29 99.9 5.1 2.7e-07 31.2 0.5 5.4 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBK25541.2 - 3e-12 46.7 0.0 0.024 14.9 0.0 5.2 2 1 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 CBK25541.2 - 5.7e-05 22.0 0.3 0.00094 17.9 0.1 2.5 1 1 2 4 4 4 1 Nucleoporin Nup120/160 CUT PF02376.15 CBK25541.2 - 0.016 15.3 0.1 0.032 14.4 0.1 1.5 1 0 0 1 1 1 0 CUT domain PALB2_WD40 PF16756.5 CBK25541.2 - 0.024 13.6 0.0 0.82 8.5 0.0 2.3 2 0 0 2 2 2 0 Partner and localizer of BRCA2 WD40 domain Ge1_WD40 PF16529.5 CBK25541.2 - 0.063 12.2 0.2 1.8 7.4 0.0 2.5 2 1 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein IL10 PF00726.17 CBK25543.2 - 0.0031 17.0 0.2 0.021 14.3 0.0 2.2 3 0 0 3 3 3 1 Interleukin 10 DCB PF16213.5 CBK25544.2 - 7.1e-16 58.4 1.0 1.3e-15 57.5 1.0 1.4 1 0 0 1 1 1 1 Dimerisation and cyclophilin-binding domain of Mon2 Sec7_N PF12783.7 CBK25544.2 - 0.017 15.0 1.1 0.91 9.4 0.1 2.3 2 0 0 2 2 2 0 Guanine nucleotide exchange factor in Golgi transport N-terminal eIF-6 PF01912.18 CBK25545.2 - 2.5e-79 265.2 0.3 4e-79 264.6 0.3 1.3 1 0 0 1 1 1 1 eIF-6 family Toprim PF01751.22 CBK25545.2 - 0.11 12.7 0.0 0.17 12.1 0.0 1.4 1 0 0 1 1 1 0 Toprim domain ATP-synt_C PF00137.21 CBK25546.2 - 3e-33 114.0 35.2 1.8e-20 73.0 15.3 2.1 2 0 0 2 2 2 2 ATP synthase subunit C KRTAP PF11759.8 CBK25546.2 - 2.9 8.5 9.1 1.6 9.3 4.0 2.2 2 0 0 2 2 2 0 Keratin-associated matrix UDPGP PF01704.18 CBK25547.2 - 0.0014 17.4 0.0 0.0017 17.1 0.0 1.0 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase HSP70 PF00012.20 CBK25548.2 - 1.7e-74 251.1 0.0 2.1e-74 250.8 0.0 1.1 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 CBK25548.2 - 7.3e-06 25.0 0.0 1.5e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 MreB/Mbl protein Cyclin PF08613.11 CBK25549.2 - 7.3e-27 94.7 1.1 7.3e-27 94.7 1.1 1.8 2 0 0 2 2 2 1 Cyclin Cyclin_N PF00134.23 CBK25549.2 - 7.5e-11 41.9 0.2 9.8e-11 41.5 0.2 1.2 1 0 0 1 1 1 1 Cyclin, N-terminal domain eIF3_subunit PF08597.10 CBK25550.2 - 4.4e-24 85.7 8.0 5.5e-24 85.4 8.0 1.1 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit FYDLN_acid PF09538.10 CBK25550.2 - 0.34 11.6 5.1 1.8 9.3 1.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) SH3_14 PF18343.1 CBK25551.2 - 0.08 13.0 3.7 0.062 13.4 1.6 2.0 2 1 0 2 2 2 0 Dda helicase SH3 domain DUF2935 PF11155.8 CBK25551.2 - 0.12 12.7 14.3 0.18 12.2 1.3 3.7 1 1 2 3 3 3 0 Domain of unknown function (DUF2935) YbjQ_1 PF01906.17 CBK25551.2 - 0.13 12.9 0.5 0.5 11.0 0.5 2.0 1 0 0 1 1 1 0 Putative heavy-metal-binding DUF2353 PF09789.9 CBK25551.2 - 0.67 9.2 53.7 2.7 7.3 24.5 2.2 1 1 1 2 2 2 0 Uncharacterized coiled-coil protein (DUF2353) Lebercilin PF15619.6 CBK25551.2 - 0.81 9.3 62.6 3.8 7.1 22.7 3.5 1 1 1 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease Tropomyosin PF00261.20 CBK25551.2 - 1.2 8.5 49.5 0.28 10.5 39.9 3.3 1 1 2 3 3 3 0 Tropomyosin Spc7 PF08317.11 CBK25551.2 - 2.3 7.0 61.0 0.57 9.0 15.4 3.2 1 1 2 3 3 3 0 Spc7 kinetochore protein Lipoprotein_6 PF01441.19 CBK25551.2 - 2.8 7.9 11.5 0.67 9.9 3.6 2.6 2 1 0 2 2 2 0 Lipoprotein Fib_alpha PF08702.10 CBK25551.2 - 2.9 8.1 53.1 0.59 10.3 13.4 3.9 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family Filament PF00038.21 CBK25551.2 - 4 6.9 65.4 4.7 6.7 20.2 3.3 1 1 2 3 3 3 0 Intermediate filament protein DUF1664 PF07889.12 CBK25551.2 - 4.1 7.5 36.7 1.9 8.5 5.6 4.4 1 1 3 4 4 4 0 Protein of unknown function (DUF1664) Fez1 PF06818.15 CBK25551.2 - 4.6 7.7 58.2 77 3.7 31.0 2.5 1 1 1 2 2 2 0 Fez1 TPR_MLP1_2 PF07926.12 CBK25551.2 - 5.1 7.2 65.7 1 9.4 14.1 4.6 1 1 3 4 4 3 0 TPR/MLP1/MLP2-like protein Rab5-bind PF09311.11 CBK25551.2 - 8.8 5.6 61.7 0.71 9.2 1.5 3.3 1 1 1 2 2 2 0 Rabaptin-like protein AAA_13 PF13166.6 CBK25551.2 - 9 4.8 45.6 0.5 9.0 20.7 2.3 1 1 1 2 2 2 0 AAA domain HTH_52 PF18576.1 CBK25552.2 - 0.094 12.9 1.6 0.24 11.7 1.6 1.7 1 1 0 1 1 1 0 Helix-turn-helix domain LRR_8 PF13855.6 CBK25553.2 - 0.0049 16.6 2.4 0.11 12.3 0.1 3.8 4 0 0 4 4 4 1 Leucine rich repeat LRR_4 PF12799.7 CBK25553.2 - 1.4 9.5 16.2 41 4.8 0.0 6.2 5 2 4 9 9 9 0 Leucine Rich repeats (2 copies) # # Program: hmmscan # Version: 3.2.1 (June 2018) # Pipeline mode: SCAN # Query file: /oak/stanford/groups/akundaje/marinovg/genomes/Stramenopiles/Blastocystis_hominis-ASM15166v1/GCA_000151665.1_ASM15166v1_protein.faa # Target file: /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm # Option settings: /oak/stanford/groups/akundaje/marinovg/programs/hmmer-3.2.1/bin/hmmscan -o /oak/stanford/groups/akundaje/marinovg/genomes/Stramenopiles/Blastocystis_hominis-ASM15166v1/GCA_000151665.1_ASM15166v1_protein.PFam32-A --tblout /oak/stanford/groups/akundaje/marinovg/genomes/Stramenopiles/Blastocystis_hominis-ASM15166v1/GCA_000151665.1_ASM15166v1_protein.PFam32-A.tblout --cpu 20 /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm /oak/stanford/groups/akundaje/marinovg/genomes/Stramenopiles/Blastocystis_hominis-ASM15166v1/GCA_000151665.1_ASM15166v1_protein.faa # Current dir: /oak/stanford/groups/akundaje/marinovg/genomes # Date: Mon Mar 25 11:00:19 2019 # [ok]