# --- full sequence ---- --- best 1 domain ---- --- domain number estimation ---- # target name accession query name accession E-value score bias E-value score bias exp reg clu ov env dom rep inc description of target #------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ ----- --- --- --- --- --- --- --- --- --------------------- PAN_4 PF14295.6 OQR80433.1 - 3.9e-29 100.3 32.0 3.2e-10 39.7 6.6 3.4 3 0 0 3 3 3 3 PAN domain PAN_1 PF00024.26 OQR80433.1 - 5.4e-19 67.9 14.4 7.7e-07 29.0 3.3 3.2 1 1 2 3 3 3 3 PAN domain E_raikovi_mat PF06360.11 OQR80433.1 - 0.0017 18.7 28.1 0.8 10.2 3.6 3.5 3 0 0 3 3 3 3 Euplotes raikovi mating pheromone MANEC PF07502.14 OQR80433.1 - 0.0046 17.2 16.3 0.62 10.4 0.7 3.2 3 0 0 3 3 3 2 MANEC domain Consortin_C PF15281.6 OQR80433.1 - 0.0063 16.5 0.0 3.1 7.8 0.0 2.3 2 0 0 2 2 2 2 Consortin C-terminus NYAP_N PF15439.6 OQR80433.1 - 0.09 12.0 2.4 0.8 8.8 0.2 2.0 2 0 0 2 2 2 0 Neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adapter VIR_N PF15912.5 OQR80433.1 - 0.56 9.8 2.8 6.8 6.2 0.2 2.0 2 0 0 2 2 2 0 Virilizer, N-terminal Prot_inhib_II PF02428.15 OQR80433.1 - 1.3 9.5 30.3 1.6 9.3 1.8 3.6 3 0 0 3 3 3 0 Potato type II proteinase inhibitor family PAN_3 PF08277.12 OQR80433.1 - 1.7 8.5 28.1 1.5 8.7 5.7 3.5 3 1 0 3 3 3 0 PAN-like domain CAP_N PF01213.19 OQR80433.1 - 4.8 6.6 5.9 14 5.0 0.5 2.1 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal PTEN_C2 PF10409.9 OQR80435.1 - 3e-21 75.6 0.0 7.3e-21 74.3 0.0 1.7 1 1 0 1 1 1 1 C2 domain of PTEN tumour-suppressor protein LRR_4 PF12799.7 OQR80437.1 - 4.5e-05 23.7 2.2 0.00013 22.3 0.5 2.6 1 1 1 2 2 2 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 OQR80437.1 - 0.088 12.6 1.4 3 7.7 0.2 2.4 1 1 0 2 2 2 0 Leucine rich repeat REV1_C PF16727.5 OQR80437.1 - 0.16 12.4 0.1 0.28 11.6 0.1 1.4 1 0 0 1 1 1 0 DNA repair protein REV1 C-terminal domain Aa_trans PF01490.18 OQR80438.1 - 5.9e-27 94.4 25.6 1.9e-24 86.2 25.6 2.0 1 1 0 1 1 1 1 Transmembrane amino acid transporter protein DUF4652 PF15525.6 OQR80439.1 - 0.14 11.9 0.0 0.21 11.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4652) EamA PF00892.20 OQR80440.1 - 1.1e-05 25.7 8.7 1.3e-05 25.4 8.7 1.0 1 0 0 1 1 1 1 EamA-like transporter family SLC35F PF06027.12 OQR80440.1 - 0.0067 16.0 4.0 0.0079 15.7 4.0 1.0 1 0 0 1 1 1 1 Solute carrier family 35 DUF2583 PF10762.9 OQR80440.1 - 5.9 7.4 6.1 1.6 9.2 2.5 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF2583) Tubulin_C PF03953.17 OQR80441.1 - 1.3e-45 154.6 0.0 1.7e-45 154.3 0.0 1.1 1 0 0 1 1 1 1 Tubulin C-terminal domain ABC2_membrane PF01061.24 OQR80444.1 - 1.2e-39 136.0 28.5 1.2e-39 136.0 28.5 1.7 2 0 0 2 2 2 1 ABC-2 type transporter PDR_assoc PF08370.11 OQR80444.1 - 1.8e-08 34.0 1.2 1.8e-08 34.0 1.2 2.8 2 0 0 2 2 2 1 Plant PDR ABC transporter associated ABC2_membrane_3 PF12698.7 OQR80444.1 - 0.00065 18.9 28.0 0.0037 16.4 28.0 1.9 1 1 0 1 1 1 1 ABC-2 family transporter protein Pkinase_Tyr PF07714.17 OQR80445.1 - 1.1e-29 103.6 0.0 1.4e-19 70.4 0.0 3.1 2 1 1 3 3 3 3 Protein tyrosine kinase Pkinase PF00069.25 OQR80445.1 - 9.7e-26 90.7 0.0 2.3e-17 63.2 0.0 3.0 2 1 1 3 3 3 3 Protein kinase domain Ank_2 PF12796.7 OQR80447.1 - 2.5e-45 152.9 0.9 4.1e-17 62.5 0.6 3.3 3 0 0 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OQR80447.1 - 2.9e-33 110.1 2.7 8.1e-05 22.7 0.0 7.8 7 1 1 8 8 8 6 Ankyrin repeat Ank PF00023.30 OQR80447.1 - 3.7e-32 109.3 8.6 2.2e-06 27.9 0.0 8.0 7 1 1 8 8 8 6 Ankyrin repeat Ank_4 PF13637.6 OQR80447.1 - 5.7e-32 109.7 2.1 2.4e-09 37.6 0.1 5.3 4 1 1 5 5 5 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 OQR80447.1 - 8.3e-30 102.5 10.1 4.8e-05 23.6 0.0 8.0 3 2 5 8 8 8 8 Ankyrin repeats (many copies) Ank_2 PF12796.7 OQR80448.1 - 5.6e-51 171.1 9.0 7.4e-19 68.1 0.7 3.1 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQR80448.1 - 9.4e-47 156.8 18.5 1.5e-10 41.4 0.1 6.6 1 1 6 7 7 7 7 Ankyrin repeats (many copies) Ank PF00023.30 OQR80448.1 - 1.7e-41 138.9 20.0 4.5e-08 33.2 0.1 6.6 6 1 1 7 7 7 6 Ankyrin repeat Ank_3 PF13606.6 OQR80448.1 - 2e-37 122.9 3.5 0.00044 20.5 0.0 7.1 7 0 0 7 7 7 6 Ankyrin repeat Ank_5 PF13857.6 OQR80448.1 - 9.1e-22 76.8 7.4 2.7e-08 33.9 0.2 5.4 2 2 4 6 6 6 5 Ankyrin repeats (many copies) Imm_superinfect PF14373.6 OQR80448.1 - 3e-09 36.6 0.7 0.82 9.6 0.0 6.1 6 0 0 6 6 6 2 Superinfection immunity protein VWA_3_C PF18571.1 OQR80448.1 - 0.00016 21.5 0.7 1.4 8.8 0.1 5.1 6 0 0 6 6 6 1 von Willebrand factor type A C-terminal domain Aida_C2 PF14186.6 OQR80449.1 - 2.8e-43 147.0 0.0 3.9e-43 146.6 0.0 1.2 1 0 0 1 1 1 1 Cytoskeletal adhesion Aida_N PF08910.10 OQR80449.1 - 2.2e-23 82.6 0.0 3.3e-23 82.0 0.0 1.3 1 0 0 1 1 1 1 Aida N-terminus DUF953 PF06110.11 OQR80453.1 - 3e-33 113.9 0.0 2.7e-18 65.7 0.0 2.1 2 0 0 2 2 2 2 Eukaryotic protein of unknown function (DUF953) Thioredoxin PF00085.20 OQR80453.1 - 0.037 14.0 0.2 3.3 7.8 0.0 3.0 3 1 0 3 3 3 0 Thioredoxin DEP PF00610.21 OQR80454.1 - 1.5e-21 76.2 0.3 4.7e-21 74.6 0.0 2.1 2 0 0 2 2 2 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) START PF01852.19 OQR80454.1 - 5.2e-10 39.1 0.1 2.3e-08 33.7 0.1 2.2 2 0 0 2 2 2 2 START domain Pkinase PF00069.25 OQR80454.1 - 6.5e-05 22.4 0.1 0.00013 21.5 0.1 1.5 1 0 0 1 1 1 1 Protein kinase domain FYVE PF01363.21 OQR80455.1 - 3.5e-06 27.0 7.7 8.8e-06 25.8 7.7 1.6 1 0 0 1 1 1 1 FYVE zinc finger zf-B_box PF00643.24 OQR80455.1 - 0.0092 16.1 2.1 0.022 14.9 2.1 1.6 1 0 0 1 1 1 1 B-box zinc finger C1_2 PF03107.16 OQR80455.1 - 0.03 14.6 4.2 0.03 14.6 4.2 1.8 2 0 0 2 2 2 0 C1 domain zf-AN1 PF01428.16 OQR80455.1 - 1.3 9.2 5.9 2.9 8.1 5.9 1.6 1 0 0 1 1 1 0 AN1-like Zinc finger DUF244 PF03112.14 OQR80456.1 - 0.09 12.6 1.4 0.63 9.9 0.0 2.1 2 0 0 2 2 2 0 Uncharacterized protein family (ORF7) DUF DDE_Tnp_4 PF13359.6 OQR80458.1 - 2.1e-18 66.5 0.0 3.5e-18 65.8 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_1 PF01609.21 OQR80458.1 - 6.5e-07 29.2 0.0 1e-06 28.6 0.0 1.3 1 0 0 1 1 1 1 Transposase DDE domain Sugar_tr PF00083.24 OQR80459.1 - 1.8e-29 103.0 7.1 2.2e-29 102.6 7.1 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OQR80459.1 - 1.1e-21 77.2 12.3 1.2e-21 77.0 12.3 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_4 PF06779.14 OQR80459.1 - 3.1e-05 23.5 6.6 5.8e-05 22.6 6.6 1.4 1 0 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB ubiquitin PF00240.23 OQR80460.1 - 0.002 17.9 2.6 0.35 10.7 0.0 4.2 6 0 0 6 6 6 2 Ubiquitin family UCH PF00443.29 OQR80460.1 - 0.0022 17.5 0.4 0.0022 17.5 0.4 1.9 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase Mg_trans_NIPA PF05653.14 OQR80461.1 - 2.8e-20 72.6 4.6 3.8e-20 72.2 4.6 1.1 1 0 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.20 OQR80461.1 - 0.00026 21.2 7.2 0.00026 21.2 7.2 2.0 2 0 0 2 2 2 1 EamA-like transporter family Fz PF01392.22 OQR80461.1 - 0.00035 21.2 6.0 0.00035 21.2 6.0 1.8 1 1 0 1 1 1 1 Fz domain EmrE PF13536.6 OQR80461.1 - 0.0021 17.7 1.4 0.0033 17.1 1.4 1.4 1 0 0 1 1 1 1 Putative multidrug resistance efflux transporter DUF5080 PF16883.5 OQR80461.1 - 0.02 15.0 1.9 0.036 14.2 1.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5080) TMEM234 PF10639.9 OQR80461.1 - 0.056 13.5 1.8 0.12 12.4 1.8 1.6 1 0 0 1 1 1 0 Putative transmembrane family 234 ABC2_membrane_5 PF13346.6 OQR80461.1 - 0.098 12.2 10.2 0.24 10.9 8.2 2.0 1 1 1 2 2 2 0 ABC-2 family transporter protein DUF2721 PF11026.8 OQR80461.1 - 4 7.3 11.9 0.37 10.7 2.0 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF2721) Nop PF01798.18 OQR80462.1 - 8.5e-66 221.7 0.0 1.3e-65 221.1 0.0 1.3 1 0 0 1 1 1 1 snoRNA binding domain, fibrillarin Aminotran_1_2 PF00155.21 OQR80464.1 - 2e-63 214.8 0.0 2.3e-63 214.6 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 OQR80464.1 - 2e-06 26.6 0.0 4.8e-06 25.4 0.0 1.5 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Beta_elim_lyase PF01212.21 OQR80464.1 - 0.00082 18.7 0.0 0.0013 18.1 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.19 OQR80464.1 - 0.0052 15.8 0.0 0.0088 15.0 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V F-actin_cap_A PF01267.17 OQR80466.1 - 4.6e-54 183.6 0.2 5.1e-54 183.5 0.2 1.0 1 0 0 1 1 1 1 F-actin capping protein alpha subunit TFIIA PF03153.13 OQR80467.1 - 7.6 6.4 8.0 8.8 6.2 8.0 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit RNase_H2_suC PF08615.11 OQR80468.1 - 2e-09 37.8 0.1 2.1e-08 34.5 0.1 1.9 1 1 0 1 1 1 1 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) ATP_transf PF09830.9 OQR80468.1 - 0.072 13.2 0.0 0.12 12.5 0.0 1.4 1 0 0 1 1 1 0 ATP adenylyltransferase MTHFR PF02219.17 OQR80469.1 - 7.4e-21 74.7 0.0 1.7e-20 73.6 0.0 1.6 2 0 0 2 2 2 1 Methylenetetrahydrofolate reductase Peptidase_C12 PF01088.21 OQR80469.1 - 0.0058 16.4 0.1 0.012 15.4 0.1 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 ADIP PF11559.8 OQR80469.1 - 0.024 14.8 5.1 0.041 14.0 5.1 1.3 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding ZapB PF06005.12 OQR80469.1 - 0.26 11.7 11.7 0.73 10.3 10.2 2.2 2 0 0 2 2 2 0 Cell division protein ZapB Ax_dynein_light PF10211.9 OQR80469.1 - 0.26 11.2 5.1 0.44 10.5 5.1 1.2 1 0 0 1 1 1 0 Axonemal dynein light chain Spc7 PF08317.11 OQR80469.1 - 0.36 9.7 6.2 0.53 9.1 6.2 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein bZIP_2 PF07716.15 OQR80469.1 - 0.6 10.2 8.7 0.45 10.6 0.4 2.4 2 0 0 2 2 2 0 Basic region leucine zipper YabA PF06156.13 OQR80469.1 - 0.68 10.6 4.9 2.3 8.9 4.9 1.9 1 1 0 1 1 1 0 Initiation control protein YabA JIP_LZII PF16471.5 OQR80469.1 - 4.1 7.7 9.6 1.6 9.0 4.5 2.3 1 1 1 2 2 2 0 JNK-interacting protein leucine zipper II HALZ PF02183.18 OQR80469.1 - 4.1 7.7 8.9 4.6 7.6 2.5 2.4 2 0 0 2 2 2 0 Homeobox associated leucine zipper DivIC PF04977.15 OQR80469.1 - 8.3 6.3 8.6 11 5.9 3.0 2.4 1 1 1 2 2 2 0 Septum formation initiator HTH_29 PF13551.6 OQR80471.1 - 0.047 13.7 0.1 0.22 11.5 0.0 2.2 2 0 0 2 2 2 0 Winged helix-turn helix HTH_23 PF13384.6 OQR80471.1 - 0.23 11.3 2.2 2.9 7.8 0.0 3.5 3 1 1 4 4 4 0 Homeodomain-like domain ROQ_II PF18386.1 OQR80471.1 - 2 8.3 3.2 23 4.9 0.0 3.6 3 1 2 5 5 5 0 Roquin II domain Peptidase_C1 PF00112.23 OQR80473.1 - 3.7e-44 151.4 3.0 4.7e-44 151.1 3.0 1.1 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.15 OQR80473.1 - 0.0033 16.3 0.3 0.0064 15.3 0.2 1.4 2 0 0 2 2 2 1 Peptidase C1-like family MCR_gamma PF02240.16 OQR80473.1 - 0.2 10.9 0.0 0.37 10.0 0.0 1.3 1 0 0 1 1 1 0 Methyl-coenzyme M reductase gamma subunit ADH_N PF08240.12 OQR80474.1 - 5.8e-25 87.3 5.2 9.9e-25 86.5 5.2 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 OQR80474.1 - 1.9e-19 70.0 0.0 3.4e-19 69.1 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 OQR80474.1 - 1.3e-10 42.4 0.0 2e-10 41.8 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 OQR80474.1 - 1.4e-06 27.8 0.0 2.8e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 OQR80474.1 - 0.0036 16.7 0.0 0.0062 15.9 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Cyt_bd_oxida_I PF01654.17 OQR80474.1 - 0.057 12.0 0.1 0.11 11.1 0.1 1.3 1 0 0 1 1 1 0 Cytochrome bd terminal oxidase subunit I Ank_4 PF13637.6 OQR80475.1 - 4e-05 24.1 1.4 0.00043 20.8 0.3 2.6 2 1 0 2 2 2 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 OQR80475.1 - 0.00015 22.3 0.1 0.0012 19.4 0.0 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OQR80475.1 - 0.011 16.2 0.1 23 6.0 0.0 3.5 3 0 0 3 3 3 0 Ankyrin repeat Sugar_tr PF00083.24 OQR80477.1 - 2.9e-37 128.6 9.0 3.8e-37 128.2 9.0 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OQR80477.1 - 3.2e-13 49.4 18.7 4.5e-13 48.9 18.2 1.3 1 1 0 1 1 1 1 Major Facilitator Superfamily RVT_1 PF00078.27 OQR80480.1 - 5e-14 52.4 0.0 6.1e-14 52.1 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Aminotran_5 PF00266.19 OQR80484.1 - 1.2e-22 80.4 0.0 1.5e-22 80.1 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 OQR80484.1 - 6.2e-06 25.6 0.1 1e-05 24.9 0.1 1.3 1 1 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 OQR80484.1 - 2.1e-05 24.0 0.1 3.1e-05 23.5 0.1 1.1 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Elicitin PF00964.17 OQR80486.1 - 0.0079 16.3 0.7 0.017 15.2 0.7 1.5 1 0 0 1 1 1 1 Elicitin Glyco_hydro_16 PF00722.21 OQR80486.1 - 0.013 15.0 0.0 0.094 12.2 0.0 2.3 1 1 0 1 1 1 0 Glycosyl hydrolases family 16 Ank PF00023.30 OQR80489.1 - 1.6e-15 56.8 0.5 2e-08 34.3 0.1 2.1 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.7 OQR80489.1 - 1.7e-14 54.2 0.0 7.3e-14 52.1 0.0 1.7 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQR80489.1 - 4.8e-14 52.5 0.3 2.8e-10 40.5 0.1 1.9 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQR80489.1 - 4.7e-13 48.1 0.0 1.1e-05 25.4 0.0 2.1 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.6 OQR80489.1 - 6e-10 39.2 0.1 4e-06 27.0 0.0 2.0 1 1 1 2 2 2 2 Ankyrin repeats (many copies) PEGA PF08308.11 OQR80489.1 - 0.0047 16.8 0.1 2.8 7.9 0.0 2.2 2 0 0 2 2 2 2 PEGA domain Glycos_transf_1 PF00534.20 OQR80490.1 - 4.8e-07 29.5 0.0 1.7e-06 27.7 0.0 2.0 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 OQR80490.1 - 4.2e-06 27.2 0.0 8.8e-06 26.2 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Ninjurin PF04923.12 OQR80490.1 - 0.076 13.0 0.6 1.6 8.7 0.0 2.3 2 0 0 2 2 2 0 Ninjurin MMR_HSR1 PF01926.23 OQR80492.1 - 3.7e-14 52.8 0.0 3.7e-13 49.6 0.0 2.2 2 0 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 OQR80492.1 - 3.3e-10 40.1 0.5 1.3e-09 38.2 0.5 1.9 1 1 0 1 1 1 1 RsgA GTPase FeoB_N PF02421.18 OQR80492.1 - 2.7e-07 30.3 0.9 1.8e-05 24.3 0.2 2.7 2 1 0 2 2 2 1 Ferrous iron transport protein B AAA_29 PF13555.6 OQR80492.1 - 0.016 15.0 0.3 0.038 13.7 0.1 1.7 2 0 0 2 2 2 0 P-loop containing region of AAA domain GTP_EFTU PF00009.27 OQR80492.1 - 0.03 13.9 0.2 1 8.8 0.1 2.4 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain MCM PF00493.23 OQR80492.1 - 0.062 12.4 0.2 0.1 11.7 0.2 1.3 1 0 0 1 1 1 0 MCM P-loop domain MeaB PF03308.16 OQR80492.1 - 0.078 11.9 2.5 0.11 11.4 0.9 2.0 1 1 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB TniB PF05621.11 OQR80492.1 - 0.16 11.3 0.0 0.26 10.7 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein Roc PF08477.13 OQR80492.1 - 0.18 12.0 0.6 0.69 10.1 0.0 2.3 2 1 1 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase ABC_tran PF00005.27 OQR80493.1 - 1e-36 126.5 0.0 1.5e-36 125.9 0.0 1.2 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 OQR80493.1 - 6.6e-11 42.1 0.4 4.1e-07 29.7 0.0 2.1 1 1 1 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 OQR80493.1 - 4e-06 26.8 0.0 4.9e-06 26.5 0.0 1.2 1 1 0 1 1 1 1 AAA ATPase domain AAA_21 PF13304.6 OQR80493.1 - 8.8e-06 25.7 0.2 0.00082 19.3 0.1 2.1 1 1 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 OQR80493.1 - 3e-05 23.7 0.8 9.8e-05 22.0 0.4 2.0 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_22 PF13401.6 OQR80493.1 - 0.0016 18.7 0.1 0.0084 16.4 0.1 2.0 1 1 0 1 1 1 1 AAA domain ABC_ATPase PF09818.9 OQR80493.1 - 0.0034 16.3 0.2 0.61 8.8 0.0 2.4 3 0 0 3 3 3 1 Predicted ATPase of the ABC class RsgA_GTPase PF03193.16 OQR80493.1 - 0.0036 17.2 0.0 0.0076 16.2 0.0 1.5 1 0 0 1 1 1 1 RsgA GTPase AAA_16 PF13191.6 OQR80493.1 - 0.0043 17.4 0.1 0.0064 16.9 0.1 1.6 1 1 0 1 1 1 1 AAA ATPase domain Zeta_toxin PF06414.12 OQR80493.1 - 0.0045 16.3 0.0 0.01 15.1 0.0 1.6 1 0 0 1 1 1 1 Zeta toxin AAA_23 PF13476.6 OQR80493.1 - 0.0052 17.3 0.1 0.01 16.3 0.1 1.5 1 0 0 1 1 1 1 AAA domain DUF87 PF01935.17 OQR80493.1 - 0.0054 16.8 0.5 0.015 15.4 0.0 1.9 2 1 0 2 2 2 1 Helicase HerA, central domain AAA_30 PF13604.6 OQR80493.1 - 0.011 15.4 0.1 0.021 14.5 0.1 1.7 1 1 0 1 1 1 0 AAA domain AAA_10 PF12846.7 OQR80493.1 - 0.015 14.3 0.1 0.041 12.8 0.0 1.7 2 0 0 2 2 2 0 AAA-like domain DUF3584 PF12128.8 OQR80493.1 - 0.028 12.0 0.0 0.039 11.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) SbcCD_C PF13558.6 OQR80493.1 - 0.037 14.3 0.8 0.54 10.5 0.8 2.2 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_24 PF13479.6 OQR80493.1 - 0.047 13.4 0.1 0.065 13.0 0.1 1.6 1 1 0 1 1 1 0 AAA domain G-alpha PF00503.20 OQR80493.1 - 0.063 12.4 0.0 0.12 11.5 0.0 1.2 1 1 0 1 1 1 0 G-protein alpha subunit DUF815 PF05673.13 OQR80493.1 - 0.071 12.2 0.0 0.11 11.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) MMR_HSR1 PF01926.23 OQR80493.1 - 0.072 13.2 0.0 0.24 11.5 0.0 1.9 2 0 0 2 2 2 0 50S ribosome-binding GTPase FtsK_SpoIIIE PF01580.18 OQR80493.1 - 0.083 12.2 0.2 0.17 11.2 0.2 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family cobW PF02492.19 OQR80493.1 - 0.093 12.3 0.1 0.22 11.1 0.0 1.7 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain ATP-synt_ab PF00006.25 OQR80493.1 - 0.095 12.3 0.0 0.35 10.5 0.0 1.7 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_14 PF13173.6 OQR80493.1 - 0.11 12.5 0.2 0.49 10.4 0.0 2.0 2 2 0 2 2 2 0 AAA domain AAA_19 PF13245.6 OQR80493.1 - 0.11 12.8 0.2 0.51 10.7 0.1 2.0 1 1 0 1 1 1 0 AAA domain AAA_18 PF13238.6 OQR80493.1 - 0.14 12.7 0.0 0.37 11.3 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_33 PF13671.6 OQR80493.1 - 0.15 12.2 0.0 0.28 11.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain Lsm_C PF14894.6 OQR80493.1 - 0.2 11.5 1.4 2.1 8.2 0.1 2.6 2 1 0 2 2 2 0 Lsm C-terminal Anoctamin PF04547.12 OQR80494.1 - 2.1e-106 356.5 23.3 2.7e-106 356.1 23.3 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel Anoct_dimer PF16178.5 OQR80494.1 - 0.044 13.5 1.1 0.1 12.3 0.2 2.0 2 0 0 2 2 2 0 Dimerisation domain of Ca+-activated chloride-channel, anoctamin DUF2116 PF09889.9 OQR80494.1 - 0.083 12.9 0.1 0.37 10.8 0.1 2.1 1 0 0 1 1 1 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) DUF2207 PF09972.9 OQR80494.1 - 2.3 6.9 9.0 1.4 7.6 0.1 2.5 1 1 1 2 2 2 0 Predicted membrane protein (DUF2207) Metallophos PF00149.28 OQR80495.1 - 3.4e-17 63.6 0.5 5.6e-17 62.9 0.5 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_C PF14008.6 OQR80495.1 - 4.9e-08 33.7 0.9 4.2e-07 30.7 0.0 2.7 3 0 0 3 3 3 1 Iron/zinc purple acid phosphatase-like protein C Pur_ac_phosph_N PF16656.5 OQR80495.1 - 0.00021 21.8 0.1 0.00055 20.5 0.1 1.7 1 0 0 1 1 1 1 Purple acid Phosphatase, N-terminal domain Metallophos_2 PF12850.7 OQR80495.1 - 0.00041 20.6 0.1 0.031 14.5 0.0 2.2 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase superfamily domain IRK_C PF17655.1 OQR80496.1 - 1.1e-29 103.2 4.7 1.2e-15 57.6 0.2 4.0 3 1 0 3 3 3 2 Inward rectifier potassium channel C-terminal domain IRK PF01007.20 OQR80496.1 - 1.2e-09 38.1 14.6 0.00011 22.1 4.0 3.8 2 2 1 3 3 3 3 Inward rectifier potassium channel transmembrane domain Ion_trans_2 PF07885.16 OQR80496.1 - 5.3e-09 35.9 19.7 2.4e-06 27.4 6.6 3.2 2 2 0 2 2 2 2 Ion channel SKI PF01202.22 OQR80496.1 - 0.042 14.0 0.0 4 7.5 0.0 2.4 2 0 0 2 2 2 0 Shikimate kinase KTI12 PF08433.10 OQR80496.1 - 0.15 11.5 0.0 5.4 6.4 0.0 2.2 2 0 0 2 2 2 0 Chromatin associated protein KTI12 Helicase_C PF00271.31 OQR80497.1 - 1.1e-33 115.8 0.1 1.1e-33 115.8 0.1 1.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ERCC3_RAD25_C PF16203.5 OQR80497.1 - 0.00046 19.5 0.1 0.00058 19.2 0.1 1.1 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase MatE PF01554.18 OQR80499.1 - 1.3e-72 242.7 88.7 7.7e-23 80.9 16.2 4.8 5 0 0 5 5 5 4 MatE BRI3BP PF14965.6 OQR80499.1 - 2.3 7.7 12.5 5.1 6.6 0.1 3.6 3 0 0 3 3 3 0 Negative regulator of p53/TP53 Oxidored-like PF09791.9 OQR80500.1 - 1.4e-07 31.0 8.1 2.2e-07 30.4 8.1 1.3 1 0 0 1 1 1 1 Oxidoreductase-like protein, N-terminal KaiB PF07689.12 OQR80500.1 - 0.0053 16.5 0.0 0.0072 16.0 0.0 1.2 1 0 0 1 1 1 1 KaiB domain Peptidase_S24 PF00717.23 OQR80502.1 - 3.2e-06 27.0 0.3 5.1e-06 26.4 0.3 1.4 1 0 0 1 1 1 1 Peptidase S24-like Glyco_hydro_6 PF01341.17 OQR80504.1 - 1.1e-45 156.7 6.2 4.8e-45 154.6 5.7 2.1 1 1 1 2 2 2 1 Glycosyl hydrolases family 6 CBM_1 PF00734.18 OQR80504.1 - 8.8e-12 44.8 8.2 8.8e-12 44.8 8.2 2.9 4 0 0 4 4 4 1 Fungal cellulose binding domain Trypan_PARP PF05887.11 OQR80504.1 - 0.096 12.7 7.5 0.05 13.6 4.9 1.8 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) PT PF04886.12 OQR80504.1 - 0.72 9.4 46.3 0.092 12.3 37.2 2.9 2 1 1 3 3 3 0 PT repeat Glutaredoxin PF00462.24 OQR80505.1 - 1.5e-12 47.5 0.1 2.3e-12 47.0 0.1 1.3 1 0 0 1 1 1 1 Glutaredoxin Thioredoxin_2 PF13098.6 OQR80505.1 - 0.024 15.1 1.0 0.065 13.7 1.0 1.8 1 1 0 1 1 1 0 Thioredoxin-like domain Pkinase PF00069.25 OQR80507.1 - 1.4e-44 152.4 0.0 1.7e-44 152.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQR80507.1 - 2.2e-44 151.7 0.0 2.6e-44 151.5 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 OQR80507.1 - 0.0026 17.1 0.0 0.0039 16.6 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 OQR80507.1 - 0.0042 15.9 0.0 0.0061 15.4 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 OQR80507.1 - 0.0069 16.3 0.0 0.011 15.7 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 OQR80507.1 - 0.05 12.5 0.0 0.062 12.2 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain DP-EP PF08985.11 OQR80507.1 - 0.056 13.6 0.0 0.096 12.9 0.0 1.4 1 0 0 1 1 1 0 DP-EP family DHHC PF01529.20 OQR80509.1 - 2.9e-34 118.0 6.8 2.9e-34 118.0 6.8 3.1 3 0 0 3 3 3 1 DHHC palmitoyltransferase Ank_4 PF13637.6 OQR80509.1 - 9.9e-26 89.8 4.1 1.3e-09 38.4 0.0 4.9 4 1 1 5 5 5 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 OQR80509.1 - 3.1e-22 79.0 2.6 5.1e-08 33.4 0.0 3.6 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OQR80509.1 - 1.3e-18 65.2 5.0 0.0024 18.2 0.0 6.1 6 0 0 6 6 6 5 Ankyrin repeat Ank_5 PF13857.6 OQR80509.1 - 3.7e-16 59.0 5.1 3.4e-05 24.0 0.0 5.4 2 2 4 6 6 6 5 Ankyrin repeats (many copies) Ank PF00023.30 OQR80509.1 - 1.2e-11 44.5 8.5 0.0077 16.6 0.0 6.3 6 1 0 6 6 6 4 Ankyrin repeat DUF4149 PF13664.6 OQR80509.1 - 0.13 12.6 0.3 0.13 12.6 0.3 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4149) IGFBP PF00219.18 OQR80509.1 - 0.35 11.6 5.3 0.67 10.6 5.3 1.4 1 0 0 1 1 1 0 Insulin-like growth factor binding protein BPD_transp_2 PF02653.16 OQR80509.1 - 0.89 8.7 8.6 0.43 9.7 0.3 2.5 3 0 0 3 3 3 0 Branched-chain amino acid transport system / permease component Radical_SAM PF04055.21 OQR80510.1 - 2.8e-29 102.6 0.3 1.4e-28 100.4 0.0 2.3 3 0 0 3 3 3 1 Radical SAM superfamily UPF0004 PF00919.20 OQR80510.1 - 3.2e-29 100.8 0.2 7e-29 99.8 0.2 1.6 1 0 0 1 1 1 1 Uncharacterized protein family UPF0004 TRAM PF01938.20 OQR80510.1 - 0.00068 19.6 0.0 0.39 10.7 0.0 2.4 2 0 0 2 2 2 2 TRAM domain Solute_trans_a PF03619.16 OQR80512.1 - 8.7e-79 264.8 18.3 1.1e-78 264.4 18.3 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha Ank_2 PF12796.7 OQR80513.1 - 2.4e-31 108.1 3.0 1.6e-09 38.2 0.0 4.2 2 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQR80513.1 - 2.6e-24 85.2 2.3 7e-05 23.3 0.1 6.1 4 1 2 6 6 6 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 OQR80513.1 - 6.3e-21 74.2 8.9 0.0034 17.7 0.2 8.0 2 1 6 8 8 8 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQR80513.1 - 3.2e-18 63.9 0.1 0.11 13.1 0.0 8.4 8 1 1 9 9 9 4 Ankyrin repeat Ank PF00023.30 OQR80513.1 - 1.2e-08 35.0 0.2 12 6.6 0.1 6.6 5 1 1 6 6 6 1 Ankyrin repeat DUF5049 PF16468.5 OQR80513.1 - 0.00014 21.7 8.9 23 5.0 0.0 7.3 3 2 5 8 8 8 1 Domain of unknown function (DUF5049) XPB_DRD PF18458.1 OQR80513.1 - 0.0035 17.2 0.1 0.44 10.5 0.0 4.1 3 2 2 5 5 5 1 Xeroderma pigmentosum group B helicase damage recognition domain Peptidase_C2 PF00648.21 OQR80514.1 - 2.4e-66 223.8 4.7 2.6e-65 220.4 4.6 2.2 1 1 0 1 1 1 1 Calpain family cysteine protease Peptidase_C2 PF00648.21 OQR80515.1 - 4.8e-52 176.8 0.1 1.4e-51 175.3 0.1 1.7 1 1 0 1 1 1 1 Calpain family cysteine protease FAD_binding_3 PF01494.19 OQR80516.1 - 0.00093 18.5 0.0 0.0011 18.3 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain DUF676 PF05057.14 OQR80517.1 - 3.8e-06 26.6 0.0 0.015 14.8 0.0 2.4 2 0 0 2 2 2 2 Putative serine esterase (DUF676) PGAP1 PF07819.13 OQR80517.1 - 0.001 18.9 0.0 0.91 9.2 0.0 3.0 3 0 0 3 3 3 2 PGAP1-like protein DUF3040 PF11239.8 OQR80517.1 - 0.0067 16.7 0.0 3 8.2 0.0 3.0 2 0 0 2 2 2 1 Protein of unknown function (DUF3040) Acetate_kinase PF00871.17 OQR80517.1 - 0.013 14.3 0.3 0.47 9.1 0.1 2.2 2 0 0 2 2 2 0 Acetokinase family DUF818 PF05677.12 OQR80517.1 - 0.063 12.2 0.2 3 6.7 0.0 2.2 2 0 0 2 2 2 0 Chlamydia CHLPS protein (DUF818) Colicin_E5 PF12106.8 OQR80517.1 - 0.18 12.1 0.2 18 5.7 0.0 2.9 2 0 0 2 2 2 0 Colicin E5 ribonuclease domain DUF4320 PF14208.6 OQR80517.1 - 0.27 11.3 1.6 1.2 9.2 0.2 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4320) DUF4307 PF14155.6 OQR80517.1 - 0.67 9.8 3.7 3.1 7.7 0.2 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4307) DSS1_SEM1 PF05160.13 OQR80517.1 - 1.3 9.2 3.2 2.4 8.3 0.2 2.3 2 0 0 2 2 2 0 DSS1/SEM1 family DUF4110 PF13422.6 OQR80518.1 - 0.18 11.9 0.7 14 5.9 0.1 3.1 1 1 0 2 2 2 0 Domain of unknown function (DUF4110) Acyl-CoA_dh_N PF02771.16 OQR80519.1 - 4.4e-30 104.6 0.0 7.8e-30 103.8 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_1 PF00441.24 OQR80519.1 - 1.6e-27 96.6 0.0 2.5e-27 95.9 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 OQR80519.1 - 3.2e-22 78.5 0.0 5e-22 77.9 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 OQR80519.1 - 3.8e-05 24.0 0.2 0.00072 19.8 0.2 2.2 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Exo_endo_phos PF03372.23 OQR80520.1 - 1.4e-24 86.9 0.0 2.2e-24 86.3 0.0 1.3 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.6 OQR80520.1 - 0.0059 16.4 0.0 0.018 14.9 0.0 1.8 1 1 0 1 1 1 1 Endonuclease-reverse transcriptase ABC_membrane PF00664.23 OQR80522.1 - 6e-21 75.3 20.5 8e-21 74.9 20.5 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 OQR80522.1 - 1.5e-08 35.3 0.0 2.9e-08 34.3 0.0 1.6 1 0 0 1 1 1 1 ABC transporter RsgA_GTPase PF03193.16 OQR80522.1 - 0.011 15.7 0.9 0.019 14.8 0.0 1.8 2 0 0 2 2 2 0 RsgA GTPase Dynamin_N PF00350.23 OQR80522.1 - 0.029 14.4 0.1 0.063 13.3 0.1 1.5 1 0 0 1 1 1 0 Dynamin family AAA_29 PF13555.6 OQR80522.1 - 0.052 13.3 0.1 0.35 10.6 0.0 2.2 2 0 0 2 2 2 0 P-loop containing region of AAA domain ABC_membrane PF00664.23 OQR80523.1 - 6e-22 78.6 16.5 8.3e-22 78.1 16.5 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 OQR80523.1 - 3e-09 37.5 0.0 8.4e-09 36.1 0.0 1.7 1 0 0 1 1 1 1 ABC transporter RsgA_GTPase PF03193.16 OQR80523.1 - 0.019 14.8 0.0 0.054 13.4 0.0 1.7 1 0 0 1 1 1 0 RsgA GTPase Oxidored_FMN PF00724.20 OQR80530.1 - 1.8e-53 182.0 0.0 1.5e-47 162.5 0.0 2.7 1 1 1 2 2 2 2 NADH:flavin oxidoreductase / NADH oxidase family Oxidored_FMN PF00724.20 OQR80531.1 - 3.1e-24 85.9 0.0 1.7e-19 70.3 0.0 3.5 1 1 1 2 2 2 2 NADH:flavin oxidoreductase / NADH oxidase family Glyco_hydro_18 PF00704.28 OQR80531.1 - 0.088 12.5 0.2 0.15 11.7 0.2 1.4 1 0 0 1 1 1 0 Glycosyl hydrolases family 18 AA_permease_2 PF13520.6 OQR80533.1 - 2e-36 125.8 29.0 6.5e-36 124.1 24.6 2.1 1 1 1 2 2 2 2 Amino acid permease AA_permease PF00324.21 OQR80533.1 - 9.1e-27 93.8 24.9 9.1e-27 93.8 24.9 1.7 2 0 0 2 2 2 1 Amino acid permease AA_permease_C PF13906.6 OQR80533.1 - 3.1e-11 43.2 3.7 3.1e-11 43.2 3.7 3.8 4 1 0 4 4 4 1 C-terminus of AA_permease DUF2700 PF10912.8 OQR80533.1 - 0.032 14.3 0.0 0.032 14.3 0.0 2.8 3 1 1 4 4 4 0 Protein of unknown function (DUF2700) DUF2070 PF09843.9 OQR80533.1 - 0.045 12.0 14.6 0.4 8.9 0.4 2.1 2 0 0 2 2 2 0 Predicted membrane protein (DUF2070) Chitin_synth_1 PF01644.17 OQR80535.1 - 9.2e-50 168.8 0.0 3.4e-49 167.0 0.0 1.9 2 0 0 2 2 2 1 Chitin synthase Chitin_synth_2 PF03142.15 OQR80535.1 - 4.4e-26 91.6 1.5 2.6e-20 72.5 0.0 2.9 3 0 0 3 3 3 2 Chitin synthase Glyco_trans_2_3 PF13632.6 OQR80535.1 - 1.4e-12 47.9 2.1 1.4e-12 47.9 2.1 1.7 2 0 0 2 2 2 1 Glycosyl transferase family group 2 MIT PF04212.18 OQR80535.1 - 1.3e-07 31.6 1.2 1.3e-07 31.6 1.2 1.8 2 0 0 2 2 2 1 MIT (microtubule interacting and transport) domain Glyco_tranf_2_3 PF13641.6 OQR80535.1 - 1.6e-05 24.9 0.0 0.00016 21.7 0.0 2.2 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Chitin_synth_1N PF08407.11 OQR80535.1 - 2.3e-05 24.3 0.2 0.00012 21.9 0.2 2.2 3 0 0 3 3 3 1 Chitin synthase N-terminal GRAM PF02893.20 OQR80535.1 - 0.019 14.9 1.8 4.7 7.1 0.6 3.0 3 1 0 3 3 3 0 GRAM domain Ank_2 PF12796.7 OQR80537.1 - 6.5e-30 103.6 5.7 3.6e-17 62.7 0.9 2.9 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OQR80537.1 - 2.9e-22 76.3 5.3 9.2e-06 25.6 0.0 6.4 5 1 1 6 6 6 4 Ankyrin repeat Ank PF00023.30 OQR80537.1 - 9.4e-22 76.4 6.9 2.8e-05 24.4 0.0 5.7 5 1 1 6 6 6 4 Ankyrin repeat Ank_5 PF13857.6 OQR80537.1 - 4.8e-21 74.6 3.4 4.8e-09 36.3 0.0 4.1 2 2 2 4 4 4 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 OQR80537.1 - 1.4e-20 73.4 5.8 3.1e-12 46.8 0.0 3.9 3 2 1 4 4 4 3 Ankyrin repeats (many copies) DHBP_synthase PF00926.19 OQR80537.1 - 0.033 13.7 0.0 0.077 12.5 0.0 1.6 1 1 1 2 2 2 0 3,4-dihydroxy-2-butanone 4-phosphate synthase Pkinase PF00069.25 OQR80541.1 - 1.9e-31 109.4 0.3 6.1e-31 107.7 0.3 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQR80541.1 - 2.1e-31 109.2 0.4 2.1e-19 69.9 0.2 2.0 1 1 0 2 2 2 2 Protein tyrosine kinase Kdo PF06293.14 OQR80541.1 - 0.0013 18.1 0.1 0.002 17.5 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 OQR80541.1 - 0.0018 17.7 0.0 0.0029 17.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Choline_kinase PF01633.20 OQR80541.1 - 0.0093 15.6 0.0 0.3 10.7 0.0 2.1 1 1 1 2 2 2 2 Choline/ethanolamine kinase FTA2 PF13095.6 OQR80541.1 - 0.026 14.2 0.0 0.036 13.7 0.0 1.3 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 FYVE PF01363.21 OQR80542.1 - 1.7e-12 47.3 10.3 4e-12 46.1 10.3 1.5 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.16 OQR80542.1 - 0.00086 19.5 6.0 0.0017 18.5 6.0 1.5 1 0 0 1 1 1 1 FYVE-type zinc finger zf-RING_5 PF14634.6 OQR80542.1 - 1.2 9.2 11.8 2 8.4 11.8 1.4 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_2 PF13923.6 OQR80543.1 - 3.9e-09 36.2 9.7 3.9e-09 36.2 9.7 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 OQR80543.1 - 8.6e-09 35.1 6.0 8.6e-09 35.1 6.0 1.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 OQR80543.1 - 2.6e-08 33.6 9.0 2.6e-08 33.6 9.0 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 OQR80543.1 - 3.4e-08 33.7 7.9 3.4e-08 33.7 7.9 1.7 2 0 0 2 2 2 1 Ring finger domain zf-RING_UBOX PF13445.6 OQR80543.1 - 1.7e-07 31.1 3.3 1.7e-07 31.1 3.3 2.4 2 1 1 3 3 3 1 RING-type zinc-finger zf-RING_5 PF14634.6 OQR80543.1 - 5.5e-07 29.4 8.9 1.7e-06 27.9 9.1 1.7 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 OQR80543.1 - 2.6e-06 27.5 6.6 2.6e-06 27.5 6.6 1.9 2 1 0 2 2 2 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 OQR80543.1 - 1.2e-05 25.1 7.3 1.2e-05 25.1 7.3 2.4 2 1 1 3 3 3 1 Prokaryotic RING finger family 4 zf-RING_10 PF16685.5 OQR80543.1 - 0.00011 22.2 4.6 0.00023 21.2 4.6 1.5 1 0 0 1 1 1 1 zinc RING finger of MSL2 zf-rbx1 PF12678.7 OQR80543.1 - 0.00019 21.7 8.6 0.00064 20.0 8.6 1.9 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-Nse PF11789.8 OQR80543.1 - 0.0031 17.3 4.6 0.0069 16.2 4.6 1.5 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-C2HC5 PF06221.13 OQR80543.1 - 0.019 14.9 2.6 0.019 14.9 2.6 2.2 2 1 1 3 3 3 0 Putative zinc finger motif, C2HC5-type zinc-ribbons_6 PF07191.12 OQR80543.1 - 0.042 13.8 3.8 0.074 13.0 3.8 1.4 1 0 0 1 1 1 0 zinc-ribbons Rad50_zn_hook PF04423.14 OQR80543.1 - 0.078 12.8 0.4 1.6 8.6 0.1 2.4 2 0 0 2 2 2 0 Rad50 zinc hook motif zf-RING_4 PF14570.6 OQR80543.1 - 1.7 8.5 11.3 3.4 7.5 9.9 2.1 2 1 1 3 3 2 0 RING/Ubox like zinc-binding domain Zn-C2H2_12 PF18112.1 OQR80543.1 - 7.5 7.1 7.1 8.8 6.9 0.8 2.7 2 0 0 2 2 2 0 Autophagy receptor zinc finger-C2H2 domain CD34_antigen PF06365.12 OQR80544.1 - 0.0089 15.6 3.6 0.031 13.9 3.6 1.7 1 1 0 1 1 1 1 CD34/Podocalyxin family DSPc PF00782.20 OQR80545.1 - 8.6e-15 54.7 0.0 2.5e-14 53.2 0.0 1.7 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 OQR80545.1 - 0.0063 16.1 1.0 0.011 15.3 0.0 1.8 2 0 0 2 2 2 1 Protein-tyrosine phosphatase Gelsolin PF00626.22 OQR80545.1 - 0.11 12.5 1.4 4.7 7.2 0.1 2.8 2 1 0 2 2 2 0 Gelsolin repeat Pkinase PF00069.25 OQR80546.1 - 1.3e-68 231.3 0.0 2e-68 230.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQR80546.1 - 6.9e-39 133.7 0.0 1.1e-38 133.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OQR80546.1 - 0.062 12.6 0.1 1.1 8.6 0.0 2.6 3 0 0 3 3 3 0 Kinase-like DUF1871 PF08958.10 OQR80546.1 - 0.086 13.2 0.1 0.68 10.3 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1871) ELK PF03789.13 OQR80546.1 - 0.1 12.7 0.3 1.5 9.0 0.1 2.4 2 0 0 2 2 2 0 ELK domain Cation_ATPase_N PF00690.26 OQR80548.1 - 1.2e-10 40.9 0.0 1.5e-10 40.6 0.0 1.1 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Cellulase PF00150.18 OQR80553.1 - 6.2e-16 58.7 0.0 8.3e-16 58.2 0.0 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) BCCT PF02028.17 OQR80553.1 - 0.1 11.0 0.0 0.14 10.6 0.0 1.1 1 0 0 1 1 1 0 BCCT, betaine/carnitine/choline family transporter E3_UbLigase_RBR PF18091.1 OQR80556.1 - 0.0015 18.7 0.1 0.0015 18.7 0.1 2.3 3 0 0 3 3 3 1 E3 Ubiquitin Ligase RBR C-terminal domain YabA PF06156.13 OQR80556.1 - 0.025 15.2 1.9 0.025 15.2 1.9 3.6 2 1 0 2 2 2 0 Initiation control protein YabA CENP-F_leu_zip PF10473.9 OQR80556.1 - 1.8 8.6 22.8 15 5.6 14.5 3.2 2 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Peptidase_S49 PF01343.18 OQR80556.1 - 3 7.8 6.9 4.8 7.1 0.5 3.0 2 1 1 3 3 3 0 Peptidase family S49 CK2S PF15011.6 OQR80556.1 - 4.2 7.2 13.3 1.9 8.3 0.4 3.3 3 1 0 3 3 3 0 Casein Kinase 2 substrate ZapB PF06005.12 OQR80556.1 - 4.8 7.7 23.9 1.3 9.5 2.7 3.8 4 1 0 4 4 4 0 Cell division protein ZapB UPF0242 PF06785.11 OQR80556.1 - 9.5 6.3 28.4 1.9 8.5 3.9 3.1 2 1 1 3 3 3 0 Uncharacterised protein family (UPF0242) N-terminus Helicase_C_2 PF13307.6 OQR80557.1 - 8.1e-59 198.6 0.0 9.8e-59 198.3 0.0 1.1 1 0 0 1 1 1 1 Helicase C-terminal domain EamA PF00892.20 OQR80558.1 - 9.2e-13 48.5 14.6 1.1e-12 48.3 14.6 1.0 1 0 0 1 1 1 1 EamA-like transporter family DUF2871 PF11070.8 OQR80558.1 - 0.14 12.4 5.1 0.25 11.6 5.1 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2871) Asp4 PF16996.5 OQR80558.1 - 0.96 9.3 6.8 8.7 6.2 0.2 3.2 3 0 0 3 3 3 0 Accessory secretory protein Sec Asp4 DUF4131 PF13567.6 OQR80558.1 - 1.9 8.1 6.6 0.49 10.0 3.5 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4131) Ank_5 PF13857.6 OQR80561.1 - 7.1e-05 23.0 0.1 0.0096 16.2 0.0 2.8 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 OQR80561.1 - 0.00087 19.8 0.2 0.0018 18.8 0.2 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQR80561.1 - 0.0026 18.3 0.1 0.013 16.1 0.1 2.2 2 1 0 2 2 2 1 Ankyrin repeats (many copies) DUF2972 PF11186.8 OQR80561.1 - 0.035 14.0 0.9 0.092 12.7 0.8 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF2972) Ank_3 PF13606.6 OQR80561.1 - 0.047 14.2 0.4 1.3 9.8 0.0 3.1 4 0 0 4 4 4 0 Ankyrin repeat Ank_2 PF12796.7 OQR80565.1 - 9.1e-78 256.9 27.4 2.2e-13 50.6 0.7 8.5 3 2 2 7 7 7 7 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OQR80565.1 - 2.9e-54 180.4 22.6 5.3e-09 36.2 0.1 10.0 5 2 4 10 10 10 9 Ankyrin repeats (many copies) Ank_4 PF13637.6 OQR80565.1 - 7e-49 163.6 13.7 1.3e-08 35.2 0.1 10.3 7 3 3 10 10 10 10 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQR80565.1 - 3e-47 153.1 18.3 0.00085 19.6 0.0 14.6 15 1 1 16 16 13 10 Ankyrin repeat Ank PF00023.30 OQR80565.1 - 1.5e-41 139.0 29.2 0.00033 21.0 0.1 13.4 13 1 0 13 13 12 10 Ankyrin repeat ABC_tran PF00005.27 OQR80565.1 - 1.6e-30 106.4 0.0 3e-30 105.5 0.0 1.5 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.23 OQR80565.1 - 6.8e-12 45.6 5.9 6.8e-12 45.6 5.9 3.0 3 0 0 3 3 3 1 ABC transporter transmembrane region Ion_trans PF00520.31 OQR80565.1 - 1.9e-09 37.1 24.0 1.9e-09 37.1 24.0 2.4 2 1 1 3 3 3 1 Ion transport protein SMC_N PF02463.19 OQR80565.1 - 0.00026 20.5 0.3 0.53 9.7 0.0 2.4 1 1 1 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 OQR80565.1 - 0.0051 16.7 0.0 0.33 10.7 0.0 2.7 1 1 1 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 OQR80565.1 - 0.026 15.0 0.0 0.071 13.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 OQR80565.1 - 0.031 14.3 0.0 0.089 12.9 0.0 1.8 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_29 PF13555.6 OQR80565.1 - 0.053 13.3 0.1 0.22 11.3 0.1 2.1 1 0 0 1 1 1 0 P-loop containing region of AAA domain IstB_IS21 PF01695.17 OQR80565.1 - 0.1 12.3 0.1 0.62 9.8 0.0 2.1 2 0 0 2 2 2 0 IstB-like ATP binding protein ATP-synt_ab PF00006.25 OQR80565.1 - 0.16 11.6 0.1 1.9 8.1 0.0 2.5 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain CSRNP_N PF16019.5 OQR80570.1 - 4.8e-06 26.7 0.5 0.012 15.6 0.3 2.6 1 1 1 2 2 2 2 Cysteine/serine-rich nuclear protein N-terminus Ank PF00023.30 OQR80573.1 - 5.1e-11 42.5 0.1 9.2e-10 38.5 0.0 2.1 2 0 0 2 2 2 1 Ankyrin repeat Ank_4 PF13637.6 OQR80573.1 - 3.5e-10 40.2 0.1 0.00014 22.4 0.0 1.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 OQR80573.1 - 8.7e-09 35.9 0.0 1.1e-08 35.6 0.0 1.2 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OQR80573.1 - 3.8e-06 26.8 0.0 6.9e-06 26.0 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeat Ank_5 PF13857.6 OQR80573.1 - 0.00089 19.5 0.1 0.0013 18.9 0.1 1.5 1 1 0 1 1 1 1 Ankyrin repeats (many copies) NAD_binding_10 PF13460.6 OQR80575.1 - 2.3e-13 50.4 0.0 7.5e-13 48.8 0.0 1.7 2 0 0 2 2 2 1 NAD(P)H-binding 3Beta_HSD PF01073.19 OQR80575.1 - 7.6e-08 31.7 0.0 6.3e-06 25.4 0.0 2.0 1 1 1 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.13 OQR80575.1 - 0.00033 20.3 0.0 0.00041 20.0 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family Herpes_UL52 PF03121.15 OQR80577.1 - 4.6e-11 42.5 1.6 6.2e-11 42.1 0.1 2.1 2 0 0 2 2 2 1 Herpesviridae UL52/UL70 DNA primase SBP_bac_8 PF13416.6 OQR80583.1 - 0.13 12.1 0.0 0.15 11.8 0.0 1.2 1 0 0 1 1 1 0 Bacterial extracellular solute-binding protein GDPD PF03009.17 OQR80586.1 - 2.1e-52 178.4 0.0 3.5e-52 177.7 0.0 1.3 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family cNMP_binding PF00027.29 OQR80586.1 - 0.18 11.9 0.0 0.34 11.0 0.0 1.4 1 0 0 1 1 1 0 Cyclic nucleotide-binding domain UPF0242 PF06785.11 OQR80587.1 - 0.00036 20.7 12.9 0.0005 20.2 12.9 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0242) N-terminus SHE3 PF17078.5 OQR80587.1 - 0.00051 19.8 5.6 0.00064 19.5 5.6 1.2 1 0 0 1 1 1 1 SWI5-dependent HO expression protein 3 GAS PF13851.6 OQR80587.1 - 0.001 18.5 13.3 0.0014 18.1 13.3 1.3 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding ADIP PF11559.8 OQR80587.1 - 0.0016 18.5 13.7 0.0021 18.2 13.7 1.1 1 0 0 1 1 1 1 Afadin- and alpha -actinin-Binding DDE_Tnp_ISL3 PF01610.17 OQR80587.1 - 0.0029 17.4 5.4 0.0036 17.1 5.4 1.1 1 0 0 1 1 1 1 Transposase MPS2 PF17060.5 OQR80587.1 - 0.011 15.0 3.3 0.012 14.9 3.3 1.1 1 0 0 1 1 1 0 Monopolar spindle protein 2 T4SS PF07996.11 OQR80587.1 - 0.013 15.9 8.0 0.017 15.6 8.0 1.1 1 0 0 1 1 1 0 Type IV secretion system proteins SYCE1 PF15233.6 OQR80587.1 - 0.025 14.6 10.4 0.033 14.3 10.4 1.1 1 0 0 1 1 1 0 Synaptonemal complex central element protein 1 CENP-H PF05837.12 OQR80587.1 - 0.036 14.5 9.7 0.056 13.9 9.7 1.4 1 0 0 1 1 1 0 Centromere protein H (CENP-H) CCDC-167 PF15188.6 OQR80587.1 - 0.053 13.9 6.6 2.4 8.5 0.3 2.5 2 1 0 2 2 2 0 Coiled-coil domain-containing protein 167 Uso1_p115_C PF04871.13 OQR80587.1 - 0.08 13.3 11.6 0.15 12.4 11.6 1.5 1 1 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region DUF4407 PF14362.6 OQR80587.1 - 0.1 11.9 6.7 0.12 11.7 6.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF4200 PF13863.6 OQR80587.1 - 0.11 13.0 12.1 0.14 12.6 12.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) PCRF PF03462.18 OQR80587.1 - 0.15 11.9 7.3 0.2 11.5 7.3 1.2 1 0 0 1 1 1 0 PCRF domain DUF3972 PF13118.6 OQR80587.1 - 0.3 11.5 6.7 5.2 7.5 0.3 2.3 1 1 0 2 2 2 0 Protein of unknown function (DUF3972) TMPIT PF07851.13 OQR80587.1 - 0.31 10.3 5.6 0.36 10.0 5.6 1.3 1 0 0 1 1 1 0 TMPIT-like protein FlaC_arch PF05377.11 OQR80587.1 - 0.44 11.0 4.1 5.9 7.4 0.2 2.6 3 0 0 3 3 2 0 Flagella accessory protein C (FlaC) Jnk-SapK_ap_N PF09744.9 OQR80587.1 - 0.64 10.2 12.1 1.3 9.2 12.1 1.5 1 1 0 1 1 1 0 JNK_SAPK-associated protein-1 FUSC PF04632.12 OQR80587.1 - 0.91 8.0 3.9 0.98 7.9 3.9 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family Exonuc_VII_L PF02601.15 OQR80587.1 - 0.99 8.9 8.0 1.1 8.8 8.0 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit PRKG1_interact PF15898.5 OQR80587.1 - 1.3 10.0 11.6 2.1 9.3 11.1 1.6 1 1 0 1 1 1 0 cGMP-dependent protein kinase interacting domain SlyX PF04102.12 OQR80587.1 - 1.6 9.4 10.1 6.4 7.5 1.5 2.5 1 1 0 2 2 2 0 SlyX THOC7 PF05615.13 OQR80587.1 - 1.7 8.9 12.7 0.33 11.2 3.9 2.1 1 1 1 2 2 2 0 Tho complex subunit 7 APG6_N PF17675.1 OQR80587.1 - 2.7 8.5 14.3 0.45 11.0 4.7 2.1 1 1 1 2 2 2 0 Apg6 coiled-coil region DUF3450 PF11932.8 OQR80587.1 - 3.3 6.9 14.8 11 5.2 14.8 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3450) MerR-DNA-bind PF09278.11 OQR80587.1 - 4 8.0 7.7 4 8.1 0.9 2.3 2 0 0 2 2 2 0 MerR, DNA binding DUF2203 PF09969.9 OQR80587.1 - 4.5 8.0 7.3 7.1 7.4 7.3 1.5 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) DivIC PF04977.15 OQR80587.1 - 4.7 7.0 19.6 1 9.2 2.9 3.1 1 1 2 3 3 3 0 Septum formation initiator DUF5595 PF18077.1 OQR80587.1 - 8.3 6.6 8.1 9.2 6.4 0.5 2.4 1 1 0 2 2 2 0 Domain of unknown function (DUF5595) ZZ PF00569.17 OQR80599.1 - 4.6e-10 39.1 0.9 8.4e-10 38.3 0.9 1.5 1 0 0 1 1 1 1 Zinc finger, ZZ type PH PF00169.29 OQR80599.1 - 1e-08 35.6 0.0 1.9e-08 34.8 0.0 1.5 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 OQR80599.1 - 0.00038 20.8 2.7 0.0034 17.8 2.7 2.1 1 1 0 1 1 1 1 Pleckstrin homology domain Ribosomal_L31e PF01198.19 OQR80600.1 - 1e-42 144.3 2.8 1.4e-42 143.8 2.8 1.2 1 0 0 1 1 1 1 Ribosomal protein L31e Vsr PF03852.15 OQR80600.1 - 0.017 15.0 0.0 0.031 14.1 0.0 1.5 1 0 0 1 1 1 0 DNA mismatch endonuclease Vsr Val_tRNA-synt_C PF10458.9 OQR80600.1 - 0.04 14.2 0.5 0.04 14.2 0.5 1.6 2 0 0 2 2 2 0 Valyl tRNA synthetase tRNA binding arm tRNA-synt_2 PF00152.20 OQR80601.1 - 1.1e-101 340.1 0.0 1.4e-101 339.7 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 OQR80601.1 - 1.2e-13 50.9 0.0 3.2e-13 49.4 0.0 1.8 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain GAD PF02938.14 OQR80601.1 - 1.7e-07 31.3 0.0 3.9e-07 30.2 0.0 1.6 1 0 0 1 1 1 1 GAD domain tRNA-synt_2d PF01409.20 OQR80601.1 - 0.0064 16.0 0.0 0.048 13.1 0.0 2.4 2 1 0 2 2 2 1 tRNA synthetases class II core domain (F) tRNA-synt_2b PF00587.25 OQR80601.1 - 0.14 12.1 0.1 0.27 11.2 0.0 1.6 2 0 0 2 2 2 0 tRNA synthetase class II core domain (G, H, P, S and T) HMA PF00403.26 OQR80604.1 - 2.9e-21 75.7 3.8 2.4e-11 43.9 0.3 2.3 2 0 0 2 2 2 2 Heavy-metal-associated domain DXPR_C PF13288.6 OQR80604.1 - 0.11 12.7 0.0 0.21 11.8 0.0 1.5 1 0 0 1 1 1 0 DXP reductoisomerase C-terminal domain zf-LITAF-like PF10601.9 OQR80604.1 - 0.15 12.3 0.5 3 8.2 0.1 2.6 2 0 0 2 2 2 0 LITAF-like zinc ribbon domain Ank_2 PF12796.7 OQR80605.1 - 1.6e-33 115.2 4.5 4.3e-12 46.5 0.2 3.2 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.30 OQR80605.1 - 8.9e-32 108.2 4.2 1.1e-05 25.6 0.0 5.2 5 0 0 5 5 5 5 Ankyrin repeat Ank_4 PF13637.6 OQR80605.1 - 1.1e-29 102.4 0.8 7.1e-09 36.0 0.0 4.2 2 1 3 5 5 5 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 OQR80605.1 - 9.5e-19 67.2 5.5 3.1e-05 24.2 0.1 5.1 2 1 3 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQR80605.1 - 4.2e-17 60.5 0.4 0.011 16.2 0.0 5.2 5 0 0 5 5 5 4 Ankyrin repeat Arg_repressor PF01316.21 OQR80605.1 - 0.25 11.1 1.0 66 3.4 0.0 3.6 4 0 0 4 4 4 0 Arginine repressor, DNA binding domain Ank_2 PF12796.7 OQR80608.1 - 0.00015 22.3 0.1 0.0023 18.5 0.1 1.8 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQR80608.1 - 0.00051 20.6 0.1 0.0012 19.4 0.1 1.7 1 1 0 1 1 1 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 OQR80608.1 - 0.00078 19.7 0.1 0.5 10.8 0.0 2.3 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQR80608.1 - 0.0039 17.6 0.1 2.9 8.7 0.0 2.9 3 2 0 3 3 3 1 Ankyrin repeat DUF3488 PF11992.8 OQR80608.1 - 0.0045 16.0 0.4 0.0047 15.9 0.4 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3488) Bunya_G2 PF03563.13 OQR80608.1 - 0.046 13.0 1.7 0.048 12.9 1.7 1.0 1 0 0 1 1 1 0 Bunyavirus glycoprotein G2 Ank PF00023.30 OQR80608.1 - 0.093 13.2 0.1 0.77 10.3 0.0 2.2 2 1 0 2 2 2 0 Ankyrin repeat Ank_2 PF12796.7 OQR80609.1 - 0.034 14.7 0.1 0.067 13.8 0.1 1.5 1 1 0 1 1 1 0 Ankyrin repeats (3 copies) Ank_2 PF12796.7 OQR80610.1 - 1.9e-45 153.4 32.6 2.6e-09 37.5 0.2 6.0 2 2 4 7 7 7 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQR80610.1 - 1.1e-39 134.3 7.6 1.3e-06 28.8 0.1 8.5 6 2 3 9 9 9 8 Ankyrin repeats (many copies) Ank_5 PF13857.6 OQR80610.1 - 7e-35 118.6 18.8 5e-05 23.5 0.2 12.2 3 3 10 13 13 13 12 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQR80610.1 - 9.9e-24 80.9 9.8 0.56 10.9 0.0 12.3 13 0 0 13 13 12 5 Ankyrin repeat DUF5049 PF16468.5 OQR80610.1 - 9.5e-15 54.2 17.2 2.5 8.1 0.1 12.1 6 3 7 13 13 13 3 Domain of unknown function (DUF5049) Ank PF00023.30 OQR80610.1 - 2.3e-06 27.8 9.7 20 5.9 0.0 10.1 6 4 3 9 9 9 0 Ankyrin repeat Tom37 PF10568.9 OQR80610.1 - 9.2e-06 26.0 2.6 13 6.1 0.1 7.1 1 1 6 7 7 7 1 Outer mitochondrial membrane transport complex protein TBPIP PF07106.13 OQR80610.1 - 0.011 15.6 0.3 22 5.1 0.0 5.0 3 3 3 7 7 7 0 TBPIP/Hop2 winged helix domain Peptidase_C23 PF05379.11 OQR80610.1 - 0.022 14.9 2.8 10 6.3 0.0 5.1 4 3 2 6 6 6 0 Carlavirus endopeptidase 4HBT_2 PF13279.6 OQR80610.1 - 0.079 13.4 6.8 12 6.4 0.3 4.9 3 2 0 3 3 3 0 Thioesterase-like superfamily DUF281 PF03436.13 OQR80610.1 - 0.96 9.9 8.7 1.7 9.1 1.5 4.4 4 1 0 4 4 4 0 Domain of unknown function (DUF281) ABC_membrane PF00664.23 OQR80612.1 - 4.5e-29 102.0 16.8 7.9e-29 101.2 16.8 1.4 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 OQR80612.1 - 2.6e-07 31.2 0.0 5.3e-07 30.2 0.0 1.5 1 0 0 1 1 1 1 ABC transporter RsgA_GTPase PF03193.16 OQR80612.1 - 0.013 15.4 0.0 0.026 14.4 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase G10 PF01125.17 OQR80612.1 - 0.076 12.8 0.3 0.14 12.0 0.3 1.3 1 0 0 1 1 1 0 G10 protein HA PF03457.14 OQR80613.1 - 2.2e-35 120.8 0.0 8.4e-08 32.4 0.0 6.4 7 0 0 7 7 7 5 Helicase associated domain Methyltransf_12 PF08242.12 OQR80621.1 - 1.5e-15 57.8 0.0 5.5e-15 55.9 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 OQR80621.1 - 2.4e-15 57.0 0.0 6.9e-15 55.5 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 OQR80621.1 - 3.4e-14 53.0 0.0 4.6e-14 52.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OQR80621.1 - 1e-12 48.5 0.0 2.1e-12 47.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OQR80621.1 - 6e-10 39.1 0.0 8.7e-10 38.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 OQR80621.1 - 2.1e-06 27.4 0.0 4.1e-06 26.4 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase small domain Ubie_methyltran PF01209.18 OQR80621.1 - 1.8e-05 24.2 0.0 2.6e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family CMAS PF02353.20 OQR80621.1 - 0.0025 17.1 0.0 0.0037 16.6 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_4 PF02390.17 OQR80621.1 - 0.057 12.9 0.0 0.82 9.1 0.0 2.6 2 1 1 3 3 3 0 Putative methyltransferase Methyltransf_2 PF00891.18 OQR80621.1 - 0.082 12.2 0.0 0.13 11.6 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase domain DRE2_N PF16803.5 OQR80621.1 - 0.13 12.5 0.0 0.3 11.3 0.0 1.6 1 0 0 1 1 1 0 Fe-S cluster assembly protein DRE2 N-terminus Ank_2 PF12796.7 OQR80622.1 - 8.7e-91 298.6 22.2 1.1e-17 64.4 0.7 5.4 1 1 6 7 7 7 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQR80622.1 - 1.2e-58 194.8 22.7 4.6e-09 36.6 0.0 8.2 1 1 8 10 10 10 10 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQR80622.1 - 4e-52 168.1 4.1 0.00024 21.3 0.0 10.1 10 0 0 10 10 10 10 Ankyrin repeat Ank PF00023.30 OQR80622.1 - 5.7e-50 165.7 32.1 7.1e-06 26.2 0.3 10.1 7 2 3 10 10 10 10 Ankyrin repeat Ank_5 PF13857.6 OQR80622.1 - 5.1e-23 80.8 18.1 1.9e-05 24.8 0.3 7.8 3 3 3 8 8 8 6 Ankyrin repeats (many copies) Imm_superinfect PF14373.6 OQR80622.1 - 2.5e-09 36.9 3.7 0.27 11.2 0.2 7.6 8 0 0 8 8 8 2 Superinfection immunity protein YfmQ PF10787.9 OQR80622.1 - 0.0001 22.1 0.0 40 4.0 0.0 6.0 2 2 4 7 7 7 0 Uncharacterised protein from bacillus cereus group VWA_3_C PF18571.1 OQR80622.1 - 0.00014 21.7 5.1 19 5.2 0.0 6.7 8 0 0 8 8 8 0 von Willebrand factor type A C-terminal domain Ubiq-assoc PF09145.10 OQR80622.1 - 0.0047 16.9 5.8 17 5.5 0.0 5.9 7 0 0 7 7 7 1 Ubiquitin-associated Pyridoxal_deC PF00282.19 OQR80622.1 - 0.0055 15.5 0.1 33 3.0 0.0 4.9 2 1 4 6 6 6 0 Pyridoxal-dependent decarboxylase conserved domain Orn_Arg_deC_N PF02784.16 OQR80626.1 - 1.5e-26 93.3 0.0 2e-26 92.8 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.22 OQR80626.1 - 2e-12 47.2 0.0 5.9e-12 45.7 0.0 1.8 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain Rad60-SLD PF11976.8 OQR80626.1 - 0.065 13.1 0.2 0.18 11.6 0.2 1.7 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Mnd1 PF03962.15 OQR80626.1 - 0.55 10.6 2.2 4.3 7.7 0.1 2.4 2 0 0 2 2 2 0 Mnd1 HTH domain EF-hand_7 PF13499.6 OQR80627.1 - 0.013 15.9 1.2 0.022 15.2 0.1 2.0 2 1 0 2 2 2 0 EF-hand domain pair EF-hand_6 PF13405.6 OQR80627.1 - 0.023 14.6 0.1 0.12 12.4 0.1 2.2 1 0 0 1 1 1 0 EF-hand domain LRR_8 PF13855.6 OQR80632.1 - 1.6e-39 133.4 51.0 9.4e-12 44.5 2.1 7.6 6 3 2 8 8 8 7 Leucine rich repeat LRR_4 PF12799.7 OQR80632.1 - 8.5e-32 108.7 57.2 1.6e-09 37.9 0.7 10.3 6 3 7 13 13 13 10 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 OQR80632.1 - 2.9e-10 39.9 18.8 0.00011 21.7 0.5 4.2 3 3 1 4 4 4 3 Leucine-rich repeat LRR_1 PF00560.33 OQR80632.1 - 6.1e-09 35.2 45.5 4.3 8.3 0.0 13.9 13 2 1 14 14 14 6 Leucine Rich Repeat DXPR_C PF13288.6 OQR80632.1 - 0.18 12.1 0.0 5.8 7.2 0.1 2.3 2 0 0 2 2 2 0 DXP reductoisomerase C-terminal domain Pkinase PF00069.25 OQR80633.1 - 1.7e-75 253.8 0.0 1.9e-75 253.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQR80633.1 - 1.5e-39 135.9 0.0 1.9e-39 135.5 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OQR80633.1 - 2.2e-07 30.5 0.0 3.5e-07 29.8 0.0 1.3 1 0 0 1 1 1 1 Kinase-like FTA2 PF13095.6 OQR80633.1 - 0.033 13.8 0.1 5.9 6.5 0.0 2.2 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 OQR80633.1 - 0.12 12.3 0.0 2.2 8.2 0.0 1.9 1 1 1 2 2 2 0 Phosphotransferase enzyme family zf-B_box PF00643.24 OQR80636.1 - 2.1 8.6 13.9 5.2 7.3 13.9 1.7 1 0 0 1 1 1 0 B-box zinc finger B2-adapt-app_C PF09066.10 OQR80638.1 - 4.1e-16 59.0 0.0 1.2e-15 57.6 0.0 1.8 2 0 0 2 2 2 1 Beta2-adaptin appendage, C-terminal sub-domain RRM_1 PF00076.22 OQR80638.1 - 1.8e-14 53.3 0.0 4.3e-14 52.1 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Adaptin_N PF01602.20 OQR80638.1 - 7e-12 44.7 0.0 1.4e-11 43.6 0.0 1.5 1 0 0 1 1 1 1 Adaptin N terminal region CTD_bind PF04818.13 OQR80638.1 - 1.2e-08 35.6 1.2 1.9e-05 25.4 0.1 4.1 4 0 0 4 4 4 1 RNA polymerase II-binding domain. Surp PF01805.20 OQR80638.1 - 2.2e-05 24.3 0.4 7.9e-05 22.6 0.1 2.1 2 0 0 2 2 2 1 Surp module SAP PF02037.27 OQR80638.1 - 0.021 14.6 0.1 0.047 13.5 0.1 1.6 1 0 0 1 1 1 0 SAP domain RRM_7 PF16367.5 OQR80638.1 - 0.038 14.1 0.0 0.12 12.5 0.0 1.9 1 0 0 1 1 1 0 RNA recognition motif BRCC36_C PF18110.1 OQR80639.1 - 0.0022 18.1 0.2 0.0037 17.4 0.2 1.4 1 0 0 1 1 1 1 BRCC36 C-terminal helical domain FYVE PF01363.21 OQR80641.1 - 5.7e-16 58.4 13.8 2.1e-15 56.6 13.0 2.1 2 0 0 2 2 2 1 FYVE zinc finger GAF PF01590.26 OQR80641.1 - 0.007 17.0 0.1 0.015 15.9 0.1 1.6 1 0 0 1 1 1 1 GAF domain SpoVT_C PF15714.5 OQR80641.1 - 0.11 12.5 0.1 0.27 11.3 0.1 1.6 1 0 0 1 1 1 0 Stage V sporulation protein T C-terminal, transcription factor DZR PF12773.7 OQR80641.1 - 0.19 11.8 9.1 17 5.6 0.0 3.4 2 1 1 3 3 3 0 Double zinc ribbon FYVE_2 PF02318.16 OQR80641.1 - 1.1 9.5 15.6 2.4 8.4 11.5 2.7 2 1 0 2 2 2 0 FYVE-type zinc finger Zf_RING PF16744.5 OQR80641.1 - 3.9 7.6 9.2 11 6.2 9.2 1.8 1 0 0 1 1 1 0 KIAA1045 RING finger C2 PF00168.30 OQR80645.1 - 8e-10 38.9 0.0 1.7e-09 37.9 0.0 1.6 1 0 0 1 1 1 1 C2 domain Plectin PF00681.20 OQR80645.1 - 0.019 14.8 0.0 0.043 13.7 0.0 1.5 1 0 0 1 1 1 0 Plectin repeat TRAP_alpha PF03896.16 OQR80645.1 - 5.6 6.1 5.9 29 3.7 2.9 2.3 2 0 0 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit KCT2 PF17818.1 OQR80646.1 - 0.015 15.4 0.0 0.027 14.6 0.0 1.4 1 0 0 1 1 1 0 Keratinocyte-associated gene product RGS PF00615.19 OQR80650.1 - 6.3e-69 229.7 3.6 1.7e-18 67.0 0.0 4.2 4 0 0 4 4 4 4 Regulator of G protein signaling domain FliL PF03748.14 OQR80650.1 - 0.013 16.1 0.2 0.11 13.1 0.0 2.6 3 1 0 3 3 3 0 Flagellar basal body-associated protein FliL IQ PF00612.27 OQR80662.1 - 7.9e-19 65.6 46.6 0.0001 21.8 0.3 8.9 8 0 0 8 8 8 6 IQ calmodulin-binding motif Aa_trans PF01490.18 OQR80662.1 - 9.5e-07 27.9 11.2 1.5e-06 27.2 11.2 1.2 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein TPR_2 PF07719.17 OQR80662.1 - 6.2e-05 22.8 7.5 1.4 9.2 0.2 5.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 OQR80662.1 - 0.032 15.1 10.6 0.85 10.6 0.3 4.9 5 0 0 5 5 5 0 Tetratricopeptide repeat ANAPC3 PF12895.7 OQR80662.1 - 0.13 12.5 0.0 0.13 12.5 0.0 2.7 3 0 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.6 OQR80662.1 - 0.4 11.0 2.8 20 5.7 0.1 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.28 OQR80662.1 - 0.43 10.5 3.8 0.8 9.6 0.2 3.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_19 PF14559.6 OQR80662.1 - 0.86 10.2 10.3 3.3 8.3 0.2 4.3 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_12 PF13424.6 OQR80662.1 - 0.97 9.8 9.9 5.3 7.4 0.3 4.6 3 1 1 4 4 4 0 Tetratricopeptide repeat DUF1804 PF08822.11 OQR80679.1 - 0.056 13.4 0.1 9.8 6.1 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1804) MORN PF02493.20 OQR80685.1 - 3.1e-36 121.1 70.7 1.2e-05 24.9 2.0 11.1 11 0 0 11 11 11 9 MORN repeat RRM_1 PF00076.22 OQR80685.1 - 0.034 14.0 0.0 0.1 12.4 0.0 1.9 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ank_5 PF13857.6 OQR80686.1 - 2e-14 53.5 2.5 0.001 19.3 0.1 5.2 3 2 2 5 5 5 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 OQR80686.1 - 4.9e-14 52.7 2.0 2.4e-07 31.2 0.6 3.1 1 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQR80686.1 - 1.8e-12 47.5 2.0 0.00013 22.5 0.0 3.4 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQR80686.1 - 9.8e-10 37.8 0.3 0.21 12.2 0.0 4.8 3 1 1 4 4 4 3 Ankyrin repeat Ank PF00023.30 OQR80686.1 - 0.00023 21.4 0.3 7.2 7.2 0.0 4.5 2 2 1 3 3 3 1 Ankyrin repeat DUF5049 PF16468.5 OQR80686.1 - 0.0044 16.9 0.4 1.5 8.8 0.0 3.8 3 1 1 4 4 4 1 Domain of unknown function (DUF5049) RabGAP-TBC PF00566.18 OQR80697.1 - 4.6e-22 78.7 1.0 1.3e-21 77.2 1.0 1.7 1 0 0 1 1 1 1 Rab-GTPase-TBC domain F-box-like PF12937.7 OQR80697.1 - 2.4e-06 27.3 0.4 3.5e-05 23.6 0.4 2.5 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 OQR80697.1 - 3.8e-05 23.5 0.2 0.00015 21.6 0.2 2.0 1 0 0 1 1 1 1 F-box domain DUF1128 PF06569.11 OQR80697.1 - 0.097 12.7 0.7 0.23 11.5 0.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1128) DUF1825 PF08855.10 OQR80697.1 - 0.25 11.3 1.3 1.9 8.4 1.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1825) TMEM43 PF07787.12 OQR80698.1 - 2.6e-41 141.7 0.3 3.5e-41 141.2 0.3 1.1 1 0 0 1 1 1 1 Transmembrane protein 43 Apolipoprotein PF01442.18 OQR80711.1 - 0.00044 20.2 14.4 0.0032 17.4 13.8 2.1 1 1 0 1 1 1 1 Apolipoprotein A1/A4/E domain ApoLp-III PF07464.11 OQR80711.1 - 0.0022 18.1 8.6 0.0022 18.1 8.6 2.1 2 0 0 2 2 2 1 Apolipophorin-III precursor (apoLp-III) DUF1664 PF07889.12 OQR80711.1 - 0.0024 17.9 6.8 0.0024 17.9 6.8 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF1664) HAD_2 PF13419.6 OQR80711.1 - 0.017 15.2 4.4 0.017 15.2 4.4 2.0 2 1 0 2 2 2 0 Haloacid dehalogenase-like hydrolase ZnuA PF01297.17 OQR80711.1 - 0.022 14.2 1.5 0.022 14.2 1.5 1.8 2 0 0 2 2 2 0 Zinc-uptake complex component A periplasmic Usg PF06233.12 OQR80711.1 - 0.048 13.8 0.3 0.13 12.5 0.2 1.8 1 1 0 1 1 1 0 Usg-like family XkdW PF09636.10 OQR80711.1 - 0.12 12.4 6.3 0.057 13.5 2.5 2.2 1 1 1 2 2 2 0 XkdW protein Baculo_PEP_C PF04513.12 OQR80711.1 - 0.13 12.4 1.9 0.42 10.6 1.9 1.8 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF3970 PF13113.6 OQR80711.1 - 0.16 12.2 0.8 1.3 9.3 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3970) DUF98 PF01947.16 OQR80711.1 - 0.29 11.1 3.9 0.35 10.8 0.9 2.2 1 1 1 2 2 2 0 p-hydroxybenzoic acid synthase DUF1640 PF07798.11 OQR80711.1 - 0.39 10.7 10.8 0.13 12.3 6.8 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1640) Fzo_mitofusin PF04799.13 OQR80711.1 - 0.74 9.3 6.5 0.099 12.2 2.2 1.9 2 0 0 2 2 2 0 fzo-like conserved region YlqD PF11068.8 OQR80711.1 - 2.1 8.7 18.4 0.07 13.5 9.5 2.4 2 0 0 2 2 2 0 YlqD protein OmpH PF03938.14 OQR80711.1 - 3.9 7.8 20.2 1.3 9.3 8.9 2.3 1 1 0 2 2 2 0 Outer membrane protein (OmpH-like) DUF883 PF05957.13 OQR80711.1 - 4.8 7.9 8.6 2 9.1 2.6 2.4 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF883) KfrA_N PF11740.8 OQR80711.1 - 4.9 7.9 12.5 12 6.6 1.1 3.2 2 1 1 3 3 3 0 Plasmid replication region DNA-binding N-term YtxH PF12732.7 OQR80711.1 - 5.5 7.6 13.4 2.1 9.0 1.5 3.4 1 1 1 2 2 2 0 YtxH-like protein HU-CCDC81_bac_2 PF18175.1 OQR80711.1 - 6.9 6.6 6.6 43 4.1 1.1 3.5 2 1 1 3 3 3 0 CCDC81-like prokaryotic HU domain 2 VSG_B PF13206.6 OQR80711.1 - 7.9 5.6 12.1 1.6 7.9 8.4 1.4 1 1 0 1 1 1 0 Trypanosomal VSG domain WD40 PF00400.32 OQR80712.1 - 5.3e-50 166.3 28.7 2e-08 34.7 0.8 7.7 8 0 0 8 8 8 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OQR80712.1 - 3.6e-16 59.2 0.1 0.02 15.2 0.0 6.9 1 1 6 7 7 7 5 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 OQR80712.1 - 3.4e-06 27.1 0.0 0.13 12.1 0.0 3.4 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 OQR80712.1 - 0.00036 19.6 5.9 0.87 8.5 0.2 4.8 1 1 3 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 OQR80712.1 - 0.00061 18.6 8.1 0.18 10.4 0.0 5.0 2 1 3 5 5 5 2 Nucleoporin Nup120/160 FlxA PF14282.6 OQR80712.1 - 0.0083 16.1 7.4 0.012 15.6 0.9 2.4 1 1 1 2 2 2 1 FlxA-like protein DUF1759 PF03564.15 OQR80712.1 - 0.054 13.4 1.4 0.11 12.4 1.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1759) IR1-M PF12185.8 OQR80712.1 - 0.44 10.5 3.5 1.3 9.0 3.5 1.8 1 0 0 1 1 1 0 Nup358/RanBP2 E3 ligase domain Fib_alpha PF08702.10 OQR80712.1 - 0.93 9.7 6.4 1.2 9.3 5.7 1.5 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family YabA PF06156.13 OQR80712.1 - 1.5 9.5 5.8 4.2 8.1 1.8 2.4 2 0 0 2 2 2 0 Initiation control protein YabA Cep57_CLD_2 PF14197.6 OQR80712.1 - 4.8 7.3 9.4 28 4.9 2.9 3.0 1 1 2 3 3 3 0 Centrosome localisation domain of PPC89 Glyco_hydro_11 PF00457.17 OQR80714.1 - 3.2e-75 251.7 18.3 3.8e-75 251.4 18.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 11 Pkinase_Tyr PF07714.17 OQR80736.1 - 2e-53 181.4 0.0 2.6e-53 181.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OQR80736.1 - 2.5e-51 174.6 0.0 3.5e-51 174.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 OQR80736.1 - 1.6e-05 23.9 0.0 2.5e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 OQR80736.1 - 7.4e-05 22.2 0.0 0.00041 19.8 0.0 2.2 3 0 0 3 3 3 1 Kinase-like Kdo PF06293.14 OQR80736.1 - 0.022 14.1 0.0 0.032 13.6 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 OQR80736.1 - 0.03 13.3 0.2 0.14 11.0 0.0 1.9 2 0 0 2 2 2 0 Haspin like kinase domain DUF4064 PF13273.6 OQR80736.1 - 0.043 14.1 1.4 0.093 13.0 1.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4064) APH PF01636.23 OQR80736.1 - 0.095 12.6 0.0 0.14 12.0 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family Syndecan PF01034.20 OQR80736.1 - 0.095 12.6 3.3 0.31 11.0 1.9 2.2 2 0 0 2 2 2 0 Syndecan domain VEGFR-2_TMD PF17988.1 OQR80736.1 - 0.17 11.4 2.0 0.38 10.2 2.0 1.6 1 0 0 1 1 1 0 VEGFR-2 Transmembrane domain Ras PF00071.22 OQR80737.1 - 1.8e-36 125.2 0.0 2e-36 125.1 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OQR80737.1 - 9.9e-12 45.1 0.0 1.2e-11 44.9 0.0 1.1 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 OQR80737.1 - 3.8e-05 23.7 0.0 4.5e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 OQR80737.1 - 0.01 15.7 0.0 0.22 11.4 0.0 2.1 1 1 1 2 2 2 0 RsgA GTPase AAA_16 PF13191.6 OQR80737.1 - 0.026 14.9 0.0 0.029 14.8 0.0 1.3 1 1 0 1 1 1 0 AAA ATPase domain EppA_BapA PF07268.11 OQR80737.1 - 0.084 12.8 0.0 0.1 12.6 0.0 1.1 1 0 0 1 1 1 0 Exported protein precursor (EppA/BapA) EF1G PF00647.19 OQR80748.1 - 8.5e-38 128.7 0.4 1.4e-37 128.0 0.4 1.3 1 0 0 1 1 1 1 Elongation factor 1 gamma, conserved domain GABP-alpha PF11620.8 OQR80748.1 - 0.055 13.7 0.0 0.09 13.0 0.0 1.4 1 0 0 1 1 1 0 GA-binding protein alpha chain Rod_C PF10493.9 OQR80750.1 - 1e-28 100.1 16.5 1e-28 100.1 16.5 2.3 2 0 0 2 2 2 1 Rough deal protein C-terminal region CH_2 PF06294.11 OQR80750.1 - 5.4e-26 90.6 0.6 1.6e-25 89.1 0.0 2.2 2 0 0 2 2 2 1 CH-like domain in sperm protein CAMSAP_CH PF11971.8 OQR80750.1 - 4.9e-08 32.7 0.3 2e-06 27.6 0.0 3.6 4 0 0 4 4 4 1 CAMSAP CH domain Cyc-maltodext_C PF10438.9 OQR80750.1 - 0.12 12.5 0.0 0.44 10.7 0.0 2.0 1 0 0 1 1 1 0 Cyclo-malto-dextrinase C-terminal domain HSP70 PF00012.20 OQR80751.1 - 7.9e-08 30.9 0.0 8.4e-08 30.9 0.0 1.0 1 0 0 1 1 1 1 Hsp70 protein E2F_TDP PF02319.20 OQR80753.1 - 2.1e-25 88.6 0.1 4.7e-25 87.4 0.1 1.6 1 0 0 1 1 1 1 E2F/DP family winged-helix DNA-binding domain Ion_trans PF00520.31 OQR80754.1 - 1.3e-30 106.4 6.1 1.9e-30 105.9 6.1 1.2 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 OQR80754.1 - 1.1e-09 38.1 0.7 1.1e-09 38.1 0.7 2.7 3 1 1 4 4 4 1 Ion channel IRK PF01007.20 OQR80754.1 - 0.0062 16.3 0.1 0.016 15.0 0.1 1.7 1 1 0 1 1 1 1 Inward rectifier potassium channel transmembrane domain COPI_assoc PF08507.10 OQR80770.1 - 1.4e-14 54.3 8.8 1.6e-14 54.0 8.8 1.1 1 0 0 1 1 1 1 COPI associated protein Pkinase PF00069.25 OQR80771.1 - 2.2e-18 66.6 0.0 6.7e-13 48.6 0.0 2.5 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OQR80771.1 - 4.5e-10 39.3 0.0 3.9e-08 32.9 0.0 2.4 2 0 0 2 2 2 2 Protein tyrosine kinase MBD PF01429.19 OQR80771.1 - 0.046 13.4 0.0 0.09 12.5 0.0 1.5 1 1 0 1 1 1 0 Methyl-CpG binding domain Kdo PF06293.14 OQR80771.1 - 0.056 12.8 0.0 0.38 10.1 0.0 2.1 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Asparaginase_2 PF01112.18 OQR80771.1 - 0.21 10.6 0.0 0.38 9.7 0.0 1.4 1 0 0 1 1 1 0 Asparaginase PAH PF02671.21 OQR80772.1 - 0.018 15.2 0.3 0.051 13.7 0.3 1.7 1 0 0 1 1 1 0 Paired amphipathic helix repeat Exonuc_VII_L PF02601.15 OQR80772.1 - 1.3 8.5 5.7 1.9 8.0 5.7 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit Oxidored_FMN PF00724.20 OQR80774.1 - 4e-93 312.4 0.0 4.6e-93 312.2 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Peptidase_C1 PF00112.23 OQR80784.1 - 5.7e-17 62.5 1.5 8.6e-17 61.9 1.5 1.3 1 0 0 1 1 1 1 Papain family cysteine protease Histone PF00125.24 OQR80785.1 - 3.3e-41 140.7 0.8 3.6e-41 140.6 0.8 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 OQR80785.1 - 0.00013 22.0 0.0 0.00016 21.8 0.0 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 OQR80785.1 - 0.00052 20.3 0.0 0.00068 20.0 0.0 1.1 1 0 0 1 1 1 1 CENP-S protein CBFD_NFYB_HMF PF00808.23 OQR80785.1 - 0.039 14.2 0.0 0.053 13.8 0.0 1.2 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 OQR80785.1 - 0.057 13.5 0.0 0.064 13.3 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Myb_DNA-binding PF00249.31 OQR80831.1 - 2.9e-39 133.0 14.4 3.6e-14 52.7 1.5 4.3 4 0 0 4 4 4 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OQR80831.1 - 3.1e-36 123.4 11.7 9e-17 61.1 0.4 4.6 3 1 2 5 5 5 3 Myb-like DNA-binding domain MADF_DNA_bdg PF10545.9 OQR80831.1 - 0.00023 21.4 9.5 0.48 10.8 0.0 4.5 4 0 0 4 4 4 2 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_4 PF13837.6 OQR80831.1 - 0.014 15.8 10.3 2.4 8.6 0.2 4.4 4 0 0 4 4 4 0 Myb/SANT-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OQR80831.1 - 0.034 14.0 0.9 0.83 9.6 0.0 3.3 4 0 0 4 4 4 0 Myb DNA-binding like Rap1_C PF11626.8 OQR80831.1 - 0.064 13.4 2.9 8.5 6.5 0.2 3.2 1 1 1 2 2 2 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain DUF1770 PF08589.10 OQR80831.1 - 0.29 12.1 7.1 0.39 11.7 5.3 2.2 1 1 0 1 1 1 0 Fungal protein of unknown function (DUF1770) Sporozoite_P67 PF05642.11 OQR80831.1 - 0.3 9.1 7.5 0.45 8.5 7.5 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Spore_III_AB PF09548.10 OQR80831.1 - 2 8.5 3.6 2.9 8.0 0.0 2.4 2 0 0 2 2 2 0 Stage III sporulation protein AB (spore_III_AB) CENP-B_dimeris PF09026.10 OQR80831.1 - 7.3 7.0 14.3 18 5.8 14.3 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain NOA36 PF06524.12 OQR80831.1 - 8.3 5.6 12.2 14 4.9 12.2 1.3 1 0 0 1 1 1 0 NOA36 protein FixS PF03597.15 OQR80833.1 - 0.47 10.2 2.4 1.7 8.4 2.4 2.1 1 0 0 1 1 1 0 Cytochrome oxidase maturation protein cbb3-type MatE PF01554.18 OQR80839.1 - 1.5e-05 24.8 29.4 0.00011 21.9 9.8 3.0 2 1 0 2 2 2 2 MatE Tyrosinase PF00264.20 OQR80840.1 - 5.9e-27 95.4 0.3 5.9e-27 95.4 0.3 1.7 2 0 0 2 2 2 1 Common central domain of tyrosinase 4HBT_3 PF13622.6 OQR80840.1 - 0.52 10.5 5.8 0.84 9.8 5.8 1.2 1 0 0 1 1 1 0 Thioesterase-like superfamily FAP PF07174.11 OQR80840.1 - 1.3 8.4 25.3 2 7.8 25.3 1.2 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) Kelch_1 PF01344.25 OQR80861.1 - 1.2e-37 127.3 7.3 7.7e-11 41.4 0.5 6.4 6 0 0 6 6 6 6 Kelch motif Kelch_4 PF13418.6 OQR80861.1 - 1.6e-33 114.4 11.3 2e-07 30.9 0.0 6.5 5 1 1 6 6 6 6 Galactose oxidase, central domain Kelch_6 PF13964.6 OQR80861.1 - 5.8e-31 105.8 8.2 8.1e-07 29.1 0.2 6.3 5 1 1 6 6 6 6 Kelch motif Kelch_3 PF13415.6 OQR80861.1 - 5.9e-30 103.0 11.0 7.8e-06 26.0 0.0 7.2 7 0 0 7 7 7 6 Galactose oxidase, central domain Kelch_5 PF13854.6 OQR80861.1 - 1e-25 89.2 14.9 0.00012 22.0 1.0 6.7 7 0 0 7 7 7 6 Kelch motif Kelch_2 PF07646.15 OQR80861.1 - 2.2e-20 71.8 10.1 0.00017 21.4 0.4 6.6 6 0 0 6 6 6 6 Kelch motif RAG2 PF03089.14 OQR80861.1 - 0.024 13.6 0.6 3.2 6.7 0.0 3.3 3 1 1 4 4 4 0 Recombination activating protein 2 Acyltransferase PF01553.21 OQR80876.1 - 1.9e-26 92.3 0.1 2.9e-26 91.7 0.1 1.3 1 0 0 1 1 1 1 Acyltransferase Ank_2 PF12796.7 OQR80881.1 - 2.3e-11 44.1 0.2 1.6e-05 25.4 0.0 3.0 4 0 0 4 4 4 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQR80881.1 - 2.3e-10 40.8 0.2 1.5e-07 31.8 0.1 3.2 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQR80881.1 - 1.7e-07 31.0 0.2 0.00099 19.4 0.0 4.4 4 0 0 4 4 4 1 Ankyrin repeat Ank PF00023.30 OQR80881.1 - 3.2e-07 30.5 0.0 0.032 14.7 0.0 3.9 4 1 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.6 OQR80881.1 - 1.9e-05 24.8 0.1 0.00025 21.2 0.0 2.4 2 0 0 2 2 2 1 Ankyrin repeats (many copies) DUF2742 PF10888.8 OQR80881.1 - 0.006 16.8 0.1 0.015 15.6 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2742) Pkinase PF00069.25 OQR80884.1 - 2.9e-16 59.6 0.2 1.8e-10 40.7 0.0 2.2 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OQR80884.1 - 1.5e-13 50.6 0.1 6e-11 42.1 0.0 2.1 1 1 1 2 2 2 2 Protein tyrosine kinase Ninjurin PF04923.12 OQR80885.1 - 0.12 12.4 1.5 0.99 9.4 0.1 2.6 2 0 0 2 2 2 0 Ninjurin Bap31_Bap29_C PF18035.1 OQR80886.1 - 0.016 15.2 0.4 0.032 14.2 0.4 1.5 1 0 0 1 1 1 0 Bap31/Bap29 cytoplasmic coiled-coil domain MatE PF01554.18 OQR80920.1 - 5.4e-15 55.4 9.0 7.2e-15 55.0 9.0 1.2 1 0 0 1 1 1 1 MatE adh_short PF00106.25 OQR80921.1 - 9.1e-15 54.6 0.0 2.1e-14 53.4 0.0 1.5 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 OQR80921.1 - 1e-08 35.1 0.0 1.6e-08 34.4 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OQR80921.1 - 0.029 14.3 0.2 0.069 13.1 0.1 1.6 2 0 0 2 2 2 0 KR domain Shikimate_DH PF01488.20 OQR80921.1 - 0.032 14.3 0.1 0.051 13.6 0.1 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase ApbA PF02558.16 OQR80921.1 - 0.055 13.1 0.0 0.094 12.4 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA B12-binding PF02310.19 OQR80921.1 - 0.064 13.3 0.3 0.71 9.9 0.4 2.4 2 1 1 3 3 3 0 B12 binding domain adh_short PF00106.25 OQR80922.1 - 4.7e-14 52.3 0.0 1.5e-13 50.6 0.0 1.7 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OQR80922.1 - 5.5e-10 39.2 0.0 8.9e-10 38.5 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Shikimate_DH PF01488.20 OQR80922.1 - 0.00053 20.1 0.0 0.0009 19.3 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Sacchrp_dh_NADP PF03435.18 OQR80922.1 - 0.05 13.9 0.0 0.087 13.1 0.0 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain KR PF08659.10 OQR80922.1 - 0.084 12.8 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 KR domain SNARE_assoc PF09335.11 OQR80926.1 - 2.7e-19 69.8 6.5 2.7e-19 69.8 6.5 2.2 3 0 0 3 3 3 1 SNARE associated Golgi protein zf-RanBP PF00641.18 OQR80930.1 - 4.9e-15 54.5 33.3 4.5e-06 25.9 4.0 3.5 3 0 0 3 3 3 3 Zn-finger in Ran binding protein and others EF-hand_7 PF13499.6 OQR80930.1 - 3e-05 24.4 3.9 0.11 13.0 0.0 3.3 3 0 0 3 3 3 2 EF-hand domain pair zf-Sec23_Sec24 PF04810.15 OQR80930.1 - 0.00043 20.3 2.2 1.8 8.7 0.1 3.7 3 0 0 3 3 3 1 Sec23/Sec24 zinc finger NAPRTase_N PF17767.1 OQR80930.1 - 0.00082 19.8 1.1 0.16 12.3 0.1 3.3 3 0 0 3 3 3 1 Nicotinate phosphoribosyltransferase (NAPRTase) N-terminal domain DUF4893 PF16233.5 OQR80930.1 - 0.0055 16.3 0.1 1.2 8.7 0.0 2.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4893) EF-hand_6 PF13405.6 OQR80930.1 - 0.066 13.2 4.5 6.9 6.9 0.0 3.9 4 0 0 4 4 4 0 EF-hand domain Vps36-NZF-N PF16988.5 OQR80930.1 - 0.4 10.1 19.0 2.6 7.5 0.8 3.9 3 0 0 3 3 3 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain Med11 PF10280.9 OQR80930.1 - 1.8 9.0 4.3 1.9 9.0 2.0 2.3 2 0 0 2 2 2 0 Mediator complex protein EF-hand_1 PF00036.32 OQR80930.1 - 3 7.6 4.8 3.2 7.5 0.0 3.1 3 0 0 3 3 3 0 EF hand FANCL_C PF11793.8 OQR80930.1 - 5.7 7.2 13.5 7 6.9 0.7 3.4 3 0 0 3 3 3 0 FANCL C-terminal domain FAT PF02259.23 OQR80931.1 - 1.2e-56 192.5 5.1 1.5e-56 192.1 1.8 2.4 2 1 0 2 2 2 1 FAT domain FRB_dom PF08771.11 OQR80931.1 - 7.1e-35 119.4 0.6 2.6e-34 117.6 0.6 2.1 1 0 0 1 1 1 1 FKBP12-rapamycin binding domain TPR_19 PF14559.6 OQR80931.1 - 0.0017 18.8 5.4 2.8 8.5 0.0 4.9 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_17 PF13431.6 OQR80931.1 - 0.005 17.1 0.3 5.9 7.5 0.0 4.1 5 0 0 5 5 5 1 Tetratricopeptide repeat Herpes_UL51 PF04540.13 OQR80931.1 - 0.11 12.2 0.1 0.25 11.1 0.1 1.6 1 0 0 1 1 1 0 Herpesvirus UL51 protein TPR_14 PF13428.6 OQR80931.1 - 4.4 8.4 9.8 85 4.4 0.0 5.9 7 1 1 8 8 8 0 Tetratricopeptide repeat DDE_Tnp_4 PF13359.6 OQR80940.1 - 3.2e-12 46.4 0.1 9.1e-12 44.9 0.0 1.9 2 1 0 2 2 2 1 DDE superfamily endonuclease Hydrolase_4 PF12146.8 OQR80952.1 - 1.1e-14 54.3 0.4 1.6e-14 53.8 0.4 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 OQR80952.1 - 3.6e-14 53.0 0.5 4.7e-14 52.7 0.5 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 OQR80952.1 - 2.2e-12 48.1 0.6 2.2e-12 48.1 0.6 1.9 2 0 0 2 2 2 1 Alpha/beta hydrolase family DUF676 PF05057.14 OQR80952.1 - 0.0013 18.3 0.1 0.0027 17.2 0.1 1.5 1 1 0 1 1 1 1 Putative serine esterase (DUF676) Esterase_phd PF10503.9 OQR80952.1 - 0.0016 18.0 0.1 0.004 16.7 0.1 1.6 1 1 0 1 1 1 1 Esterase PHB depolymerase Esterase PF00756.20 OQR80952.1 - 0.0023 17.6 0.1 0.09 12.4 0.0 2.1 2 0 0 2 2 2 1 Putative esterase BAAT_C PF08840.11 OQR80952.1 - 0.0088 16.0 0.1 0.045 13.7 0.0 1.9 1 1 1 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_2 PF02230.16 OQR80952.1 - 0.018 14.9 0.0 0.84 9.4 0.0 2.1 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Abhydro_lipase PF04083.16 OQR80952.1 - 0.032 13.8 0.1 0.062 12.9 0.1 1.5 1 0 0 1 1 1 0 Partial alpha/beta-hydrolase lipase region Asp2 PF16929.5 OQR80952.1 - 0.033 13.2 0.0 0.046 12.7 0.0 1.2 1 0 0 1 1 1 0 Accessory Sec system GspB-transporter Abhydrolase_3 PF07859.13 OQR80952.1 - 0.043 13.7 0.6 0.14 12.0 0.1 2.0 1 1 0 2 2 2 0 alpha/beta hydrolase fold LIDHydrolase PF10230.9 OQR80952.1 - 0.088 12.3 0.1 0.23 11.0 0.0 1.7 2 0 0 2 2 2 0 Lipid-droplet associated hydrolase Lipase_3 PF01764.25 OQR80952.1 - 0.089 12.7 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) Palm_thioest PF02089.15 OQR80952.1 - 0.12 12.2 0.0 0.15 11.9 0.0 1.1 1 0 0 1 1 1 0 Palmitoyl protein thioesterase MINDY_DUB PF04424.13 OQR80952.1 - 0.17 11.9 0.4 0.34 11.0 0.4 1.4 1 0 0 1 1 1 0 MINDY deubiquitinase Pkinase PF00069.25 OQR80954.1 - 1e-11 44.8 1.2 5.9e-11 42.2 0.1 2.5 2 1 0 2 2 2 1 Protein kinase domain EF-hand_1 PF00036.32 OQR80954.1 - 1.3e-10 40.0 1.0 5.2e-05 22.5 0.9 2.6 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 OQR80954.1 - 5.6e-10 39.5 1.4 1e-08 35.5 0.4 2.2 1 1 1 2 2 2 2 EF-hand domain pair Pkinase_Tyr PF07714.17 OQR80954.1 - 2.5e-09 36.8 0.1 1.6e-08 34.1 0.1 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase EF-hand_8 PF13833.6 OQR80954.1 - 2.6e-07 30.4 1.6 1.8e-06 27.7 0.4 2.5 1 1 1 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 OQR80954.1 - 4.2e-07 29.4 0.1 0.027 14.4 0.0 2.8 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 OQR80954.1 - 2.5e-06 26.7 2.4 0.0071 15.8 0.0 2.5 2 0 0 2 2 2 2 EF hand Ferlin_C PF16165.5 OQR80961.1 - 0.04 13.9 0.8 0.1 12.5 0.8 1.6 1 0 0 1 1 1 0 Ferlin C-terminus Radical_SAM_C PF16199.5 OQR80961.1 - 0.06 13.4 0.1 7.8 6.6 0.0 2.8 2 0 0 2 2 2 0 Radical_SAM C-terminal domain Bacillus_HBL PF05791.11 OQR80961.1 - 0.13 12.1 6.7 1.1 9.1 3.9 2.8 2 0 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) Arm PF00514.23 OQR80968.1 - 1e-57 190.5 27.8 4.2e-12 45.7 0.0 9.5 9 0 0 9 9 9 8 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 OQR80968.1 - 2.8e-17 62.8 9.5 3.6e-07 30.5 0.1 6.5 6 1 1 7 7 7 4 HEAT-like repeat HEAT_2 PF13646.6 OQR80968.1 - 5.1e-16 58.8 1.8 1.1e-05 25.7 0.0 5.3 3 2 3 6 6 5 5 HEAT repeats HEAT PF02985.22 OQR80968.1 - 9.1e-12 44.2 8.9 0.087 13.1 0.0 7.8 8 0 0 8 8 7 3 HEAT repeat NopRA1 PF16201.5 OQR80968.1 - 8e-07 28.8 0.5 0.0011 18.6 0.0 3.7 3 1 1 4 4 4 1 Nucleolar pre-ribosomal-associated protein 1 Arm_2 PF04826.13 OQR80968.1 - 1.9e-06 27.6 0.1 0.011 15.1 0.0 2.7 2 1 1 3 3 3 3 Armadillo-like Arm_3 PF16186.5 OQR80968.1 - 9.1e-06 25.1 0.0 0.086 12.4 0.0 2.9 2 0 0 2 2 2 2 Atypical Arm repeat V-ATPase_H_C PF11698.8 OQR80968.1 - 0.0008 19.5 0.0 0.66 10.1 0.0 4.2 4 1 1 5 5 5 1 V-ATPase subunit H DUF3361 PF11841.8 OQR80968.1 - 0.0013 18.7 0.0 1.8 8.5 0.0 2.9 2 1 0 2 2 2 2 Domain of unknown function (DUF3361) RICTOR_V PF14668.6 OQR80968.1 - 0.0042 17.3 3.5 5 7.4 0.1 4.6 4 2 1 5 5 5 1 Rapamycin-insensitive companion of mTOR, domain 5 PHC2_SAM_assoc PF16616.5 OQR80968.1 - 0.057 14.2 9.0 0.11 13.3 9.0 1.4 1 0 0 1 1 1 0 Unstructured region on Polyhomeotic-like protein 1 and 2 Afi1 PF07792.12 OQR80968.1 - 0.079 13.4 7.5 0.18 12.3 7.5 1.6 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking DUF1168 PF06658.12 OQR80968.1 - 0.091 12.6 20.2 0.15 11.9 20.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1168) UPF0561 PF10573.9 OQR80968.1 - 0.12 12.5 5.6 0.22 11.6 5.6 1.4 1 0 0 1 1 1 0 Uncharacterised protein family UPF0561 CTNNBL PF08216.11 OQR80968.1 - 0.19 11.9 8.4 4 7.7 0.0 5.0 6 0 0 6 6 6 0 Catenin-beta-like, Arm-motif containing nuclear Smg8_Smg9 PF10220.9 OQR80968.1 - 0.26 9.5 12.0 0.38 9.0 12.0 1.1 1 0 0 1 1 1 0 Smg8_Smg9 NPR3 PF03666.13 OQR80968.1 - 2.8 6.6 11.6 4 6.1 11.6 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 DUF4407 PF14362.6 OQR80968.1 - 2.8 7.2 6.6 5.2 6.3 6.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) RraB PF06877.11 OQR80971.1 - 0.16 12.7 0.3 2.9 8.7 0.0 2.7 3 0 0 3 3 3 0 Regulator of ribonuclease activity B RT_RNaseH PF17917.1 OQR80972.1 - 4.4e-09 36.6 0.0 5.3e-09 36.3 0.0 1.1 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 OQR80972.1 - 0.068 13.2 0.0 0.11 12.6 0.0 1.6 1 1 0 1 1 1 0 RNase H-like domain found in reverse transcriptase Tombus_movement PF05318.12 OQR80974.1 - 0.86 10.5 4.3 14 6.6 3.8 2.3 2 0 0 2 2 2 0 Tombusvirus movement protein LpxC PF03331.13 OQR80989.1 - 4.7e-57 193.5 0.0 5.2e-57 193.4 0.0 1.0 1 0 0 1 1 1 1 UDP-3-O-acyl N-acetylglycosamine deacetylase Ank PF00023.30 OQR80990.1 - 5.1e-10 39.4 0.6 9.1e-06 25.9 0.0 3.7 4 0 0 4 4 4 1 Ankyrin repeat Ank_4 PF13637.6 OQR80990.1 - 1.1e-09 38.6 0.0 4.5e-05 23.9 0.0 2.6 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 OQR80990.1 - 4.6e-08 33.5 0.1 1.6e-07 31.8 0.0 1.9 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OQR80990.1 - 2e-05 24.6 0.0 0.0083 16.6 0.0 3.7 4 0 0 4 4 4 1 Ankyrin repeat Ank_5 PF13857.6 OQR80990.1 - 0.00084 19.6 0.0 0.0031 17.8 0.0 2.0 2 1 1 3 3 3 1 Ankyrin repeats (many copies) PIG-S PF10510.9 OQR80991.1 - 2.9e-77 260.7 10.0 3.1e-76 257.3 10.0 1.9 1 1 0 1 1 1 1 Phosphatidylinositol-glycan biosynthesis class S protein Ank PF00023.30 OQR80992.1 - 1.1e-23 82.6 4.0 1.9e-07 31.2 0.2 3.3 3 0 0 3 3 3 3 Ankyrin repeat Ank_2 PF12796.7 OQR80992.1 - 8.5e-21 74.4 1.7 6.4e-14 52.3 0.6 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQR80992.1 - 3.3e-20 72.2 1.5 1.1e-10 41.8 0.1 3.2 1 1 3 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQR80992.1 - 5.7e-19 66.2 1.0 7.5e-05 22.8 0.0 3.3 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.6 OQR80992.1 - 8.5e-15 54.6 3.9 3.1e-07 30.5 0.3 3.2 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Biotin_lipoyl_2 PF13533.6 OQR80992.1 - 7.7 6.4 7.1 7.8 6.4 0.0 3.3 4 0 0 4 4 4 0 Biotin-lipoyl like SRPRB PF09439.10 OQR80994.1 - 9.4e-23 80.6 0.0 1.1e-22 80.4 0.0 1.0 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Arf PF00025.21 OQR80994.1 - 3.3e-10 39.7 0.0 3.8e-10 39.5 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 OQR80994.1 - 3.7e-07 30.4 0.0 5e-07 30.0 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 OQR80994.1 - 1.1e-05 25.5 0.0 1.4e-05 25.1 0.0 1.1 1 0 0 1 1 1 1 50S ribosome-binding GTPase Ras PF00071.22 OQR80994.1 - 0.0002 21.0 0.0 0.00025 20.7 0.0 1.1 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 OQR80994.1 - 0.00023 20.6 0.0 0.00029 20.3 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_22 PF13401.6 OQR80994.1 - 0.007 16.7 0.0 0.01 16.1 0.0 1.5 1 1 0 1 1 1 1 AAA domain DUF4024 PF13216.6 OQR80994.1 - 0.022 14.7 0.2 0.049 13.6 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4024) TsaE PF02367.17 OQR80994.1 - 0.022 14.8 0.1 0.028 14.4 0.1 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE GTP_EFTU PF00009.27 OQR80994.1 - 0.022 14.3 0.2 0.44 10.1 0.1 2.0 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain FeoB_N PF02421.18 OQR80994.1 - 0.037 13.6 0.0 0.053 13.1 0.0 1.3 1 0 0 1 1 1 0 Ferrous iron transport protein B AAA_18 PF13238.6 OQR80994.1 - 0.039 14.5 0.0 0.11 13.0 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_PrkA PF08298.11 OQR80994.1 - 0.052 12.4 0.0 0.067 12.1 0.0 1.3 1 0 0 1 1 1 0 PrkA AAA domain SRP54 PF00448.22 OQR80994.1 - 0.057 13.0 0.3 1.2 8.7 0.0 2.2 1 1 1 2 2 2 0 SRP54-type protein, GTPase domain RsgA_GTPase PF03193.16 OQR80994.1 - 0.057 13.3 0.0 0.081 12.8 0.0 1.2 1 0 0 1 1 1 0 RsgA GTPase AAA_16 PF13191.6 OQR80994.1 - 0.067 13.6 0.4 0.11 12.9 0.2 1.5 2 0 0 2 2 1 0 AAA ATPase domain PduV-EutP PF10662.9 OQR80994.1 - 0.074 12.8 0.0 0.13 12.0 0.0 1.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Mg_chelatase PF01078.21 OQR80994.1 - 0.096 12.1 0.0 0.12 11.7 0.0 1.2 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 OQR80994.1 - 0.1 12.8 0.1 0.12 12.5 0.1 1.3 1 1 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 OQR80994.1 - 0.11 12.4 0.0 1.2 9.0 0.0 2.0 1 1 1 2 2 2 0 ATPase domain predominantly from Archaea cobW PF02492.19 OQR80994.1 - 0.13 11.8 0.2 0.22 11.1 0.0 1.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_5 PF07728.14 OQR80994.1 - 0.14 12.1 0.0 0.18 11.8 0.0 1.2 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Tir_receptor_C PF07489.11 OQR80994.1 - 0.23 11.4 0.0 0.3 11.0 0.0 1.1 1 0 0 1 1 1 0 Translocated intimin receptor (Tir) C-terminus MMR_HSR1 PF01926.23 OQR80995.1 - 6.9e-05 22.9 0.2 0.00059 19.9 0.0 2.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase RHD3 PF05879.12 OQR80995.1 - 0.00015 20.1 0.0 0.00015 20.1 0.0 3.2 3 0 0 3 3 3 1 Root hair defective 3 GTP-binding protein (RHD3) Dynamin_N PF00350.23 OQR80995.1 - 0.00083 19.5 2.1 0.0015 18.6 0.1 2.4 2 1 0 2 2 2 1 Dynamin family FeoB_N PF02421.18 OQR80995.1 - 0.014 14.9 0.1 0.037 13.6 0.1 1.7 1 0 0 1 1 1 0 Ferrous iron transport protein B AAA_16 PF13191.6 OQR80995.1 - 0.19 12.1 0.0 0.83 10.0 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain DUF2408 PF10303.9 OQR80995.1 - 0.68 10.5 8.1 0.089 13.4 1.4 3.1 3 1 0 3 3 3 0 Protein of unknown function (DUF2408) FKBP_C PF00254.28 OQR80996.1 - 4.1e-32 110.4 0.0 4.6e-32 110.2 0.0 1.0 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Ribosomal_L36 PF00444.18 OQR80997.1 - 4.2e-21 74.9 12.0 5.4e-21 74.5 12.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L36 FBP_C PF16571.5 OQR80997.1 - 0.021 14.4 0.4 0.023 14.2 0.4 1.1 1 0 0 1 1 1 0 FBP C-terminal treble-clef zinc-finger Metallophos PF00149.28 OQR81000.1 - 1.5e-32 113.8 0.0 2.2e-32 113.2 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 OQR81000.1 - 0.0041 17.5 0.1 0.0075 16.7 0.1 1.4 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain DUF5378 PF17349.2 OQR81000.1 - 0.075 12.4 0.0 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5378) Metallophos_2 PF12850.7 OQR81000.1 - 0.16 12.2 0.0 0.24 11.6 0.0 1.3 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain IQ PF00612.27 OQR81008.1 - 3.1e-14 51.3 67.0 0.016 15.0 1.8 10.8 10 0 0 10 10 10 8 IQ calmodulin-binding motif zf-B_box PF00643.24 OQR81008.1 - 0.17 12.0 13.2 0.34 11.1 13.2 1.4 1 0 0 1 1 1 0 B-box zinc finger DUF2689 PF10894.8 OQR81008.1 - 0.23 11.3 2.5 2.4 8.0 0.9 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2689) IBR PF01485.21 OQR81008.1 - 0.61 10.3 11.3 1.8 8.9 11.3 1.7 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain CEBP_ZZ PF16366.5 OQR81008.1 - 3.1 8.1 14.8 1 9.6 11.5 1.9 2 0 0 2 2 2 0 Cytoplasmic polyadenylation element-binding protein ZZ domain CAP PF00188.26 OQR81038.1 - 3.1e-08 34.5 0.3 3.2e-08 34.5 0.3 1.1 1 0 0 1 1 1 1 Cysteine-rich secretory protein family KH_dom-like PF14714.6 OQR81039.1 - 0.028 14.7 0.9 0.048 14.0 0.9 1.4 1 0 0 1 1 1 0 KH-domain-like of EngA bacterial GTPase enzymes, C-terminal Aa_trans PF01490.18 OQR81041.1 - 1.4e-33 116.2 23.2 1.9e-33 115.8 23.2 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 OQR81041.1 - 2.6e-06 26.7 8.5 2.6e-06 26.7 8.5 3.0 2 1 0 3 3 3 2 Tryptophan/tyrosine permease family Flp1_like PF16982.5 OQR81041.1 - 0.023 14.1 0.6 0.069 12.5 0.6 1.9 1 0 0 1 1 1 0 Putative Flagellin, Flp1-like, domain DUF4731 PF15875.5 OQR81041.1 - 0.19 11.9 0.2 0.19 11.9 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4731) Acyl-CoA_dh_M PF02770.19 OQR81062.1 - 7.9e-13 48.4 0.0 6.1e-12 45.6 0.0 2.0 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_ox_N PF14749.6 OQR81062.1 - 6.6e-09 36.4 0.7 1.7e-08 35.0 0.7 1.8 1 1 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Las1 PF04031.13 OQR81062.1 - 0.038 14.1 0.0 0.18 11.9 0.0 1.9 2 0 0 2 2 2 0 Las1-like Arv1 PF04161.13 OQR81063.1 - 6.3e-44 150.6 7.9 7.8e-44 150.3 7.9 1.1 1 0 0 1 1 1 1 Arv1-like family HypA PF01155.19 OQR81063.1 - 0.14 12.2 0.9 0.23 11.5 0.9 1.3 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Metallophos PF00149.28 OQR81066.1 - 1.6e-08 35.3 0.0 2.7e-08 34.6 0.0 1.3 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 OQR81066.1 - 0.027 14.7 0.0 0.17 12.1 0.0 1.9 1 1 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain PGA_cap PF09587.10 OQR81066.1 - 0.055 12.9 0.6 0.48 9.8 0.6 2.3 1 1 0 1 1 1 0 Bacterial capsule synthesis protein PGA_cap Pkinase_Tyr PF07714.17 OQR81070.1 - 1.2e-56 191.9 0.0 1.6e-56 191.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OQR81070.1 - 6.1e-55 186.4 0.0 8.2e-55 186.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 OQR81070.1 - 0.0041 15.9 0.0 0.0062 15.4 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 OQR81070.1 - 0.056 12.8 0.1 0.08 12.3 0.1 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 OQR81070.1 - 0.2 11.2 0.1 0.35 10.4 0.1 1.4 1 0 0 1 1 1 0 RIO1 family C2 PF00168.30 OQR81096.1 - 3e-12 46.7 0.1 9.4e-12 45.1 0.1 1.9 1 0 0 1 1 1 1 C2 domain PH PF00169.29 OQR81096.1 - 4.9e-12 46.3 0.1 3.2e-11 43.7 0.0 2.3 2 0 0 2 2 2 1 PH domain PDZ PF00595.24 OQR81096.1 - 3.1e-08 33.9 0.1 0.0084 16.4 0.0 2.8 2 0 0 2 2 2 2 PDZ domain PDZ_6 PF17820.1 OQR81096.1 - 5.3e-07 29.4 0.0 0.0017 18.2 0.0 2.8 2 0 0 2 2 2 2 PDZ domain PH_11 PF15413.6 OQR81096.1 - 9.7e-07 29.2 0.4 6.7e-06 26.5 0.0 2.8 2 0 0 2 2 2 1 Pleckstrin homology domain PDZ_2 PF13180.6 OQR81096.1 - 0.00079 19.7 0.1 1.3 9.4 0.0 2.8 2 0 0 2 2 2 2 PDZ domain ATP-synt_B PF00430.18 OQR81096.1 - 0.01 15.9 17.3 0.01 15.9 17.3 4.8 4 2 2 6 6 6 0 ATP synthase B/B' CF(0) WH2 PF02205.20 OQR81096.1 - 0.04 13.7 6.3 3.1 7.7 0.3 3.9 4 0 0 4 4 4 0 WH2 motif RsgA_GTPase PF03193.16 OQR81097.1 - 0.046 13.6 0.1 0.1 12.5 0.0 1.6 2 0 0 2 2 2 0 RsgA GTPase AAA_16 PF13191.6 OQR81097.1 - 0.069 13.5 0.0 0.15 12.5 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain ACOX PF01756.19 OQR81098.1 - 7.7e-41 139.6 0.0 2.2e-40 138.1 0.0 1.8 1 1 0 1 1 1 1 Acyl-CoA oxidase ADP_PFK_GK PF04587.15 OQR81099.1 - 0.036 12.7 3.8 0.052 12.1 3.8 1.2 1 0 0 1 1 1 0 ADP-specific Phosphofructokinase/Glucokinase conserved region PH_BEACH PF14844.6 OQR81099.1 - 0.061 13.4 0.1 0.11 12.6 0.1 1.5 1 0 0 1 1 1 0 PH domain associated with Beige/BEACH Atg14 PF10186.9 OQR81099.1 - 0.18 10.9 4.6 0.24 10.4 4.6 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 SNF2_N PF00176.23 OQR81106.1 - 7.7e-50 169.6 0.8 2.5e-49 167.9 0.8 1.8 1 1 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.15 OQR81106.1 - 1.1e-12 48.3 0.0 2.3e-12 47.3 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF3535 PF12054.8 OQR81106.1 - 6.4e-05 22.4 2.1 0.00013 21.3 2.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3535) HEAT PF02985.22 OQR81106.1 - 0.00026 21.0 0.5 2.3 8.7 0.0 4.1 3 0 0 3 3 3 2 HEAT repeat SWI2_SNF2 PF18766.1 OQR81106.1 - 0.0019 17.9 0.0 0.0044 16.7 0.0 1.6 1 0 0 1 1 1 1 SWI2/SNF2 ATPase HEAT_2 PF13646.6 OQR81106.1 - 0.0025 18.2 0.1 3.2 8.2 0.0 4.4 4 0 0 4 4 4 1 HEAT repeats Dabb PF07876.12 OQR81146.1 - 2.3e-19 69.8 0.1 2.5e-19 69.7 0.1 1.0 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain E1-E2_ATPase PF00122.20 OQR81147.1 - 1.3e-25 90.0 0.1 2.9e-25 88.9 0.1 1.5 1 0 0 1 1 1 1 E1-E2 ATPase Calreticulin PF00262.18 OQR81148.1 - 1.2e-80 271.1 15.8 6.5e-59 199.6 7.2 2.4 2 1 1 3 3 3 2 Calreticulin family CBM77 PF18283.1 OQR81148.1 - 0.083 13.3 0.0 0.15 12.5 0.0 1.3 1 0 0 1 1 1 0 Carbohydrate binding module 77 HCMV_UL139 PF12507.8 OQR81148.1 - 0.68 10.3 4.4 0.73 10.2 3.2 1.6 2 0 0 2 2 2 0 Human Cytomegalovirus UL139 protein CDC45 PF02724.14 OQR81148.1 - 2.5 6.3 11.6 3.7 5.7 11.6 1.2 1 0 0 1 1 1 0 CDC45-like protein Syntaphilin PF15290.6 OQR81196.1 - 0.018 14.7 0.7 0.037 13.7 0.7 1.6 1 1 0 1 1 1 0 Golgi-localised syntaxin-1-binding clamp IQ PF00612.27 OQR81197.1 - 3.1e-06 26.5 25.5 0.0013 18.4 0.1 5.9 5 0 0 5 5 5 3 IQ calmodulin-binding motif WW PF00397.26 OQR81197.1 - 4.4e-05 23.5 6.6 0.021 14.9 0.7 2.8 2 0 0 2 2 2 2 WW domain Herpes_UL1 PF05259.11 OQR81197.1 - 0.011 15.8 0.0 5.6 7.1 0.0 2.8 2 0 0 2 2 2 0 Herpesvirus glycoprotein L Macoilin PF09726.9 OQR81198.1 - 0.00012 20.8 0.6 0.00014 20.6 0.6 1.0 1 0 0 1 1 1 1 Macoilin family BLOC1_2 PF10046.9 OQR81198.1 - 0.025 14.9 0.9 0.053 13.8 0.9 1.5 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 ZapB PF06005.12 OQR81198.1 - 0.051 14.0 8.9 0.13 12.7 8.9 1.6 1 0 0 1 1 1 0 Cell division protein ZapB Fungal_TACC PF12709.7 OQR81198.1 - 0.097 13.1 2.9 0.1 13.0 1.4 1.9 2 0 0 2 2 2 0 Fungal Transforming acidic coiled-coil (TACC) proteins Takusan PF04822.13 OQR81198.1 - 0.11 12.4 3.8 0.54 10.2 1.7 2.4 1 1 1 2 2 2 0 Takusan DivIC PF04977.15 OQR81198.1 - 0.53 10.1 6.9 1.7 8.5 5.8 2.1 1 1 1 2 2 2 0 Septum formation initiator CENP-H PF05837.12 OQR81198.1 - 1.1 9.7 8.0 0.53 10.7 4.7 2.0 2 1 0 2 2 2 0 Centromere protein H (CENP-H) OTU PF02338.19 OQR81199.1 - 5.9e-07 30.0 0.1 3.3e-06 27.6 0.0 2.1 2 0 0 2 2 2 1 OTU-like cysteine protease Peptidase_C65 PF10275.9 OQR81199.1 - 0.012 15.1 0.6 0.027 13.9 0.0 1.9 2 1 0 2 2 2 0 Peptidase C65 Otubain DDHD PF02862.17 OQR81199.1 - 0.014 15.5 2.0 0.016 15.4 2.0 1.1 1 0 0 1 1 1 0 DDHD domain DUF4174 PF13778.6 OQR81199.1 - 0.015 15.8 1.1 0.053 14.0 1.0 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4174) FAM178 PF14816.6 OQR81199.1 - 0.02 13.9 0.2 0.02 13.9 0.2 2.0 1 1 1 2 2 2 0 Family of unknown function, FAM178 Borrelia_P83 PF05262.11 OQR81199.1 - 0.031 12.8 12.5 0.034 12.7 12.5 1.0 1 0 0 1 1 1 0 Borrelia P83/100 protein MscS_TM PF12794.7 OQR81199.1 - 0.19 10.5 1.1 0.33 9.8 1.1 1.4 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 T4SS PF07996.11 OQR81199.1 - 0.25 11.8 4.9 13 6.2 2.2 2.2 1 1 1 2 2 2 0 Type IV secretion system proteins NCKAP5 PF15246.6 OQR81199.1 - 3.4 7.2 16.4 1.3 8.5 1.0 2.1 2 0 0 2 2 2 0 Nck-associated protein 5, Peripheral clock protein zf-BED PF02892.15 OQR81219.1 - 3e-09 36.7 0.9 5e-09 36.0 0.9 1.4 1 0 0 1 1 1 1 BED zinc finger Dimer_Tnp_hAT PF05699.14 OQR81219.1 - 0.029 14.1 0.0 0.068 13.0 0.0 1.7 1 0 0 1 1 1 0 hAT family C-terminal dimerisation region LAGLIDADG_3 PF14528.6 OQR81219.1 - 0.047 14.0 0.0 0.11 12.9 0.0 1.6 1 0 0 1 1 1 0 LAGLIDADG-like domain DUF4451 PF14616.6 OQR81219.1 - 0.087 13.0 0.1 0.18 12.0 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4451) zf-H2C2_5 PF13909.6 OQR81219.1 - 0.14 11.9 0.3 0.32 10.8 0.3 1.6 1 0 0 1 1 1 0 C2H2-type zinc-finger domain TBCA PF02970.16 OQR81221.1 - 4.8e-23 81.3 3.4 5.5e-23 81.1 3.4 1.1 1 0 0 1 1 1 1 Tubulin binding cofactor A TAP42 PF04177.12 OQR81221.1 - 0.017 14.2 2.5 0.018 14.2 2.5 1.0 1 0 0 1 1 1 0 TAP42-like family BLOC1_2 PF10046.9 OQR81221.1 - 0.032 14.5 0.3 0.042 14.1 0.3 1.2 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF2570 PF10828.8 OQR81221.1 - 0.032 14.0 1.3 0.044 13.6 1.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2570) ISG65-75 PF11727.8 OQR81221.1 - 0.054 12.7 0.8 0.057 12.7 0.8 1.1 1 0 0 1 1 1 0 Invariant surface glycoprotein Ank_4 PF13637.6 OQR81222.1 - 6.6e-12 45.7 0.2 0.0048 17.5 0.0 4.2 2 1 1 4 4 4 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 OQR81222.1 - 6.6e-09 36.2 0.0 1e-05 26.0 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OQR81222.1 - 8.3e-07 29.2 0.7 0.053 13.9 0.0 4.1 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQR81222.1 - 4.9e-06 26.5 0.1 12 6.9 0.0 5.3 4 1 1 5 5 5 1 Ankyrin repeat DUF1843 PF08898.10 OQR81222.1 - 0.053 14.0 0.1 0.84 10.2 0.0 2.9 5 0 0 5 5 5 0 Domain of unknown function (DUF1843) DEAD PF00270.29 OQR81223.1 - 1.1e-10 41.5 0.0 2.7e-10 40.3 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase zf-GRF PF06839.12 OQR81223.1 - 2.8e-10 40.1 1.0 4.8e-10 39.4 1.0 1.4 1 0 0 1 1 1 1 GRF zinc finger ResIII PF04851.15 OQR81223.1 - 0.00011 22.3 0.0 0.00052 20.1 0.0 2.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Kri1 PF05178.12 OQR81223.1 - 2.9 8.5 9.1 24 5.5 5.8 2.4 2 0 0 2 2 2 0 KRI1-like family Metallophos PF00149.28 OQR81224.1 - 1.9e-07 31.8 0.4 6.4e-07 30.1 0.4 1.9 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase NIF PF03031.18 OQR81225.1 - 3.7e-40 137.2 0.3 4.7e-40 136.9 0.3 1.1 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Myb_DNA-binding PF00249.31 OQR81227.1 - 2e-43 146.3 7.7 2.4e-14 53.3 0.3 3.2 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OQR81227.1 - 5.5e-37 125.8 0.4 7.6e-15 54.9 0.1 3.4 1 1 2 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OQR81227.1 - 0.011 15.6 0.0 0.9 9.5 0.0 2.6 2 0 0 2 2 2 0 Myb DNA-binding like SLIDE PF09111.10 OQR81227.1 - 0.011 15.7 0.0 3.7 7.6 0.0 2.8 2 1 0 2 2 2 0 SLIDE KI67R PF08065.12 OQR81227.1 - 0.06 13.9 0.5 11 6.6 0.1 2.6 1 1 1 2 2 2 0 KI67R (NUC007) repeat Myb_DNA-bind_2 PF08914.11 OQR81227.1 - 0.08 13.1 0.2 14 5.9 0.0 3.1 3 0 0 3 3 3 0 Rap1 Myb domain Rap1_C PF11626.8 OQR81227.1 - 0.11 12.6 2.2 9.7 6.4 0.1 3.2 1 1 1 2 2 2 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain Myb_DNA-bind_4 PF13837.6 OQR81227.1 - 0.45 10.9 2.0 25 5.3 0.0 3.0 3 0 0 3 3 3 0 Myb/SANT-like DNA-binding domain zf-met2 PF12907.7 OQR81271.1 - 0.012 15.7 0.6 0.04 14.1 0.6 1.9 1 1 0 1 1 1 0 Zinc-binding BK_channel_a PF03493.18 OQR81283.1 - 1.4e-21 76.5 0.0 3.9e-21 75.1 0.0 1.8 1 0 0 1 1 1 1 Calcium-activated BK potassium channel alpha subunit Ion_trans_2 PF07885.16 OQR81283.1 - 2e-12 46.9 0.7 2e-12 46.9 0.7 2.2 2 0 0 2 2 2 1 Ion channel Ion_trans PF00520.31 OQR81283.1 - 4.3e-11 42.5 10.8 9.5e-11 41.4 10.8 1.5 1 0 0 1 1 1 1 Ion transport protein TrkA_N PF02254.18 OQR81283.1 - 0.00069 19.9 0.0 0.076 13.3 0.0 2.5 2 0 0 2 2 2 1 TrkA-N domain Mannosyl_trans3 PF11051.8 OQR81285.1 - 5.9e-14 52.1 0.0 1.2e-13 51.1 0.0 1.4 1 0 0 1 1 1 1 Mannosyltransferase putative Cyclin_N PF00134.23 OQR81293.1 - 4e-05 23.4 0.8 0.00028 20.6 0.1 2.4 2 0 0 2 2 2 1 Cyclin, N-terminal domain TFIIB PF00382.19 OQR81293.1 - 0.033 14.2 2.0 3.5 7.7 0.2 2.4 2 0 0 2 2 2 0 Transcription factor TFIIB repeat Biopterin_H PF00351.21 OQR81296.1 - 2.1e-149 497.1 0.1 2.9e-149 496.6 0.1 1.1 1 0 0 1 1 1 1 Biopterin-dependent aromatic amino acid hydroxylase ACT PF01842.25 OQR81296.1 - 4.5e-06 26.3 0.0 9e-06 25.4 0.0 1.5 1 0 0 1 1 1 1 ACT domain CBS PF00571.28 OQR81297.1 - 2.8e-11 43.7 0.2 0.0028 18.1 0.0 3.5 3 0 0 3 3 3 3 CBS domain PX PF00787.24 OQR81297.1 - 2.9e-09 36.9 0.0 6.2e-09 35.8 0.0 1.5 1 0 0 1 1 1 1 PX domain EVE PF01878.18 OQR81298.1 - 4.7e-06 26.7 0.0 5.3e-06 26.5 0.0 1.1 1 0 0 1 1 1 1 EVE domain Adaptin_N PF01602.20 OQR81300.1 - 4.1e-80 269.8 9.6 5.6e-80 269.4 9.6 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Coatomer_b_Cpla PF14806.6 OQR81300.1 - 2.4e-57 192.4 0.0 6.3e-57 191.1 0.0 1.8 1 0 0 1 1 1 1 Coatomer beta subunit appendage platform Coatamer_beta_C PF07718.12 OQR81300.1 - 8.6e-48 161.8 0.0 1.9e-47 160.7 0.0 1.6 1 0 0 1 1 1 1 Coatomer beta C-terminal region HEAT_2 PF13646.6 OQR81300.1 - 1.2e-07 32.0 4.7 0.02 15.2 0.0 5.8 4 3 2 6 6 6 2 HEAT repeats Cnd1 PF12717.7 OQR81300.1 - 6.8e-07 29.5 3.6 5.2e-06 26.6 0.1 3.2 2 1 1 3 3 3 1 non-SMC mitotic condensation complex subunit 1 Coatomer_g_Cpla PF16381.5 OQR81300.1 - 7.7e-05 22.8 0.1 0.00064 19.8 0.0 2.5 2 1 1 3 3 3 1 Coatomer subunit gamma-1 C-terminal appendage platform HEAT PF02985.22 OQR81300.1 - 0.01 16.0 0.3 4.6 7.8 0.1 4.3 4 0 0 4 4 4 0 HEAT repeat MMS22L_C PF14911.6 OQR81300.1 - 0.032 13.3 0.9 7.9 5.4 0.0 2.6 2 0 0 2 2 2 0 S-phase genomic integrity recombination mediator, C-terminal HEAT_EZ PF13513.6 OQR81300.1 - 0.13 12.8 0.1 52 4.5 0.1 3.6 2 0 0 2 2 2 0 HEAT-like repeat Ank_2 PF12796.7 OQR81301.1 - 1e-15 58.1 9.4 3.9e-05 24.2 1.0 4.3 3 1 1 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQR81301.1 - 5.8e-10 39.5 10.1 0.042 14.4 0.0 6.7 3 2 1 5 5 5 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 OQR81301.1 - 1e-07 32.0 8.9 0.34 11.3 0.2 7.8 4 4 5 9 9 9 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQR81301.1 - 2e-07 30.7 10.5 8.9 7.2 0.1 9.1 9 0 0 9 9 9 1 Ankyrin repeat MRG PF05712.13 OQR81301.1 - 0.023 14.0 0.4 0.042 13.2 0.4 1.5 1 1 0 1 1 1 0 MRG Ank PF00023.30 OQR81301.1 - 0.055 13.9 0.9 3.1e+02 2.1 0.0 5.4 4 3 0 4 4 4 0 Ankyrin repeat Pecanex_C PF05041.15 OQR81302.1 - 1.1e-27 97.1 0.0 2.5e-27 95.9 0.0 1.5 1 0 0 1 1 1 1 Pecanex protein (C-terminus) ABC_tran PF00005.27 OQR81303.1 - 1.3e-13 51.7 0.0 1.5e-13 51.5 0.0 1.0 1 0 0 1 1 1 1 ABC transporter RsgA_GTPase PF03193.16 OQR81303.1 - 2.5e-05 24.2 0.0 2.8e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 RsgA GTPase AAA_29 PF13555.6 OQR81303.1 - 0.00017 21.2 0.1 0.00031 20.4 0.1 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.6 OQR81303.1 - 0.00046 20.6 0.0 0.00047 20.6 0.0 1.1 1 0 0 1 1 1 1 AAA ATPase domain AAA_21 PF13304.6 OQR81303.1 - 0.0011 18.9 0.0 0.0011 18.9 0.0 1.0 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_33 PF13671.6 OQR81303.1 - 0.0034 17.5 0.0 0.0036 17.5 0.0 1.1 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 OQR81303.1 - 0.004 16.5 0.0 0.0044 16.3 0.0 1.1 1 0 0 1 1 1 1 Zeta toxin cobW PF02492.19 OQR81303.1 - 0.005 16.4 0.0 0.0057 16.2 0.0 1.2 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_23 PF13476.6 OQR81303.1 - 0.0053 17.3 0.0 0.0081 16.7 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.6 OQR81303.1 - 0.015 14.9 0.1 0.018 14.6 0.1 1.2 1 1 0 1 1 1 0 AAA domain Guanylate_kin PF00625.21 OQR81303.1 - 0.028 14.1 0.0 0.053 13.2 0.0 1.4 1 1 1 2 2 2 0 Guanylate kinase AAA_30 PF13604.6 OQR81303.1 - 0.043 13.5 0.0 0.047 13.4 0.0 1.2 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 OQR81303.1 - 0.07 13.2 0.0 0.097 12.8 0.0 1.4 1 1 0 1 1 1 0 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 OQR81303.1 - 0.097 12.0 0.2 0.17 11.2 0.1 1.4 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region ATPase_2 PF01637.18 OQR81303.1 - 0.097 12.6 0.0 0.15 12.0 0.0 1.3 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea AAA PF00004.29 OQR81303.1 - 0.11 13.0 0.0 0.12 12.9 0.0 1.1 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 OQR81303.1 - 0.13 12.2 0.0 0.16 12.0 0.0 1.3 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 OQR81303.1 - 0.14 12.4 0.0 0.16 12.2 0.0 1.2 1 1 0 1 1 1 0 AAA domain AAA_18 PF13238.6 OQR81303.1 - 0.16 12.5 0.0 0.18 12.3 0.0 1.1 1 0 0 1 1 1 0 AAA domain SMC_N PF02463.19 OQR81303.1 - 0.17 11.3 0.1 0.24 10.8 0.1 1.3 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain 60KD_IMP PF02096.20 OQR81304.1 - 3.5e-16 59.6 0.3 5.9e-16 58.8 0.3 1.3 1 0 0 1 1 1 1 60Kd inner membrane protein Glyco_hydro_72 PF03198.14 OQR81305.1 - 2.4e-09 36.9 0.0 1.1e-07 31.5 0.0 2.4 2 1 0 2 2 2 2 Glucanosyltransferase ADH_N PF08240.12 OQR81306.1 - 5.4e-25 87.4 6.4 1.1e-24 86.4 6.4 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 OQR81306.1 - 3.6e-21 75.5 0.0 7.4e-21 74.5 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 OQR81306.1 - 3.6e-08 34.5 0.0 5.4e-08 34.0 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 OQR81306.1 - 2.6e-06 26.9 0.1 4.3e-06 26.2 0.1 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 OQR81306.1 - 0.0027 17.1 0.0 0.0047 16.3 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain GFO_IDH_MocA PF01408.22 OQR81306.1 - 0.042 14.7 0.2 0.12 13.2 0.2 1.8 1 1 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_7 PF13241.6 OQR81306.1 - 0.055 13.9 0.0 0.1 13.0 0.0 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding Methyltransf_11 PF08241.12 OQR81306.1 - 0.16 12.6 0.0 0.33 11.6 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain DUF678 PF05077.12 OQR81306.1 - 0.16 12.1 2.8 7 6.9 0.9 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF678) EMC1_C PF07774.13 OQR81307.1 - 1.1e-44 152.7 0.0 2.2e-44 151.7 0.0 1.6 1 0 0 1 1 1 1 ER membrane protein complex subunit 1, C-terminal PQQ_2 PF13360.6 OQR81307.1 - 1.1e-08 35.0 5.0 0.00015 21.4 0.0 3.3 4 1 0 4 4 4 2 PQQ-like domain PQQ PF01011.21 OQR81307.1 - 0.0023 17.8 0.1 0.065 13.2 0.0 3.3 3 0 0 3 3 3 1 PQQ enzyme repeat PALB2_WD40 PF16756.5 OQR81307.1 - 0.027 13.4 0.1 0.052 12.5 0.1 1.4 1 0 0 1 1 1 0 Partner and localizer of BRCA2 WD40 domain ESX-1_EspG PF14011.6 OQR81307.1 - 0.068 12.8 0.0 0.27 10.8 0.0 2.0 2 0 0 2 2 2 0 EspG family ubiquitin PF00240.23 OQR81308.1 - 0.051 13.3 0.1 0.27 11.0 0.0 2.2 1 1 1 2 2 2 0 Ubiquitin family TPR_2 PF07719.17 OQR81309.1 - 7.5e-09 35.0 1.5 0.026 14.6 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 OQR81309.1 - 4.5e-05 23.1 0.1 0.04 13.6 0.0 2.3 2 0 0 2 2 2 2 TPR repeat TPR_14 PF13428.6 OQR81309.1 - 0.00018 22.0 2.6 0.66 11.0 0.3 3.6 1 1 3 4 4 4 2 Tetratricopeptide repeat TPR_17 PF13431.6 OQR81309.1 - 0.00051 20.2 1.0 0.2 12.1 0.0 3.0 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 OQR81309.1 - 0.0007 20.1 2.2 0.34 11.4 0.6 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 OQR81309.1 - 0.0017 18.4 0.5 0.053 13.8 0.1 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.28 OQR81309.1 - 0.0036 17.1 0.7 0.23 11.4 0.1 2.7 3 0 0 3 3 3 1 Tetratricopeptide repeat KASH_CCD PF14662.6 OQR81309.1 - 0.0061 16.4 2.9 0.031 14.1 0.7 2.1 2 0 0 2 2 2 1 Coiled-coil region of CCDC155 or KASH ANAPC3 PF12895.7 OQR81309.1 - 0.088 13.0 0.3 0.51 10.6 0.3 2.1 1 1 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 DUF3762 PF12591.8 OQR81309.1 - 0.12 12.6 0.1 3.2 8.1 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3762) CaM_bdg_C0 PF10562.9 OQR81309.1 - 0.13 12.3 1.1 0.13 12.3 1.1 2.0 2 0 0 2 2 2 0 Calmodulin-binding domain C0 of NMDA receptor NR1 subunit Ank_5 PF13857.6 OQR81310.1 - 2.6e-26 91.3 1.7 8.4e-09 35.5 0.0 4.0 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_4 PF13637.6 OQR81310.1 - 1.3e-24 86.3 0.6 2.2e-10 40.8 0.1 3.9 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 OQR81310.1 - 2.8e-22 79.1 0.2 1.1e-15 58.0 0.1 2.7 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OQR81310.1 - 4.8e-20 69.5 0.2 5.2e-07 29.5 0.0 4.6 5 0 0 5 5 5 4 Ankyrin repeat Ank PF00023.30 OQR81310.1 - 5.6e-17 61.4 0.7 4.1e-05 23.8 0.0 4.6 5 0 0 5 5 5 4 Ankyrin repeat DUF4985 PF16373.5 OQR81310.1 - 0.05 14.1 0.0 0.069 13.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function ATPase_2 PF01637.18 OQR81311.1 - 0.02 14.8 0.0 0.032 14.1 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea Yippee-Mis18 PF03226.14 OQR81311.1 - 0.13 12.4 0.0 0.29 11.3 0.0 1.5 1 0 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly WD40 PF00400.32 OQR81312.1 - 3.6e-52 173.2 16.7 1.4e-06 28.9 0.2 8.3 8 0 0 8 8 8 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OQR81312.1 - 2.2e-15 56.7 1.2 0.036 14.4 0.0 6.8 2 1 5 7 7 7 5 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 OQR81312.1 - 3.5e-08 32.5 6.3 0.018 13.7 0.0 5.0 3 2 2 5 5 5 3 Nucleoporin Nup120/160 WD40_like PF17005.5 OQR81312.1 - 4e-08 32.9 0.0 0.015 14.6 0.0 3.2 1 1 2 3 3 3 3 WD40-like domain Ge1_WD40 PF16529.5 OQR81312.1 - 9.7e-05 21.5 9.4 0.1 11.5 0.5 5.2 2 1 2 5 5 5 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Nt_Gln_amidase PF09764.9 OQR81312.1 - 0.024 14.2 0.2 0.041 13.5 0.2 1.4 1 0 0 1 1 1 0 N-terminal glutamine amidase Ras PF00071.22 OQR81313.1 - 7e-65 217.6 0.6 8.2e-65 217.3 0.6 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OQR81313.1 - 2.5e-35 121.3 0.2 3.8e-35 120.7 0.2 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OQR81313.1 - 2.9e-17 62.7 0.1 3.8e-17 62.3 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 OQR81313.1 - 3.2e-07 30.1 0.4 8.3e-07 28.7 0.2 1.7 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 OQR81313.1 - 2.3e-06 27.2 0.2 2.6e-06 26.9 0.2 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.20 OQR81313.1 - 0.00049 19.4 1.1 0.041 13.0 0.4 2.8 1 1 1 2 2 2 1 G-protein alpha subunit RsgA_GTPase PF03193.16 OQR81313.1 - 0.00053 19.9 0.0 1.1 9.2 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase SRPRB PF09439.10 OQR81313.1 - 0.00091 18.7 0.1 0.0012 18.3 0.1 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 OQR81313.1 - 0.0014 18.7 0.1 0.0023 18.0 0.1 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Ser_hydrolase PF06821.13 OQR81313.1 - 0.007 16.2 0.1 0.014 15.2 0.1 1.4 1 1 0 1 1 1 1 Serine hydrolase AAA PF00004.29 OQR81313.1 - 0.017 15.6 0.0 0.25 11.8 0.0 2.4 1 1 1 2 2 2 0 ATPase family associated with various cellular activities (AAA) FeoB_N PF02421.18 OQR81313.1 - 0.067 12.7 0.2 0.33 10.5 0.2 2.0 1 1 0 1 1 1 0 Ferrous iron transport protein B PduV-EutP PF10662.9 OQR81313.1 - 0.077 12.7 0.1 0.16 11.7 0.1 1.7 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Septin PF00735.18 OQR81313.1 - 0.078 12.2 0.1 0.19 11.0 0.1 1.6 1 1 0 1 1 1 0 Septin AAA_7 PF12775.7 OQR81313.1 - 0.08 12.5 0.0 0.15 11.6 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region Helicase_C PF00271.31 OQR81314.1 - 3.3e-24 85.4 0.0 1.1e-23 83.7 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 OQR81314.1 - 6.6e-21 74.3 0.1 1.8e-20 72.9 0.1 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) Myb_DNA-binding PF00249.31 OQR81315.1 - 4.1e-13 49.3 1.1 2.8e-12 46.6 0.7 2.3 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OQR81315.1 - 0.0014 18.8 0.2 0.0049 17.1 0.1 2.0 2 0 0 2 2 2 1 Myb-like DNA-binding domain fn3 PF00041.21 OQR81316.1 - 3.3e-07 30.5 0.0 1e-06 29.0 0.0 1.8 1 0 0 1 1 1 1 Fibronectin type III domain WW PF00397.26 OQR81316.1 - 1.8e-05 24.7 0.8 3.2e-05 23.9 0.8 1.4 1 0 0 1 1 1 1 WW domain RIO1 PF01163.22 OQR81317.1 - 1.5e-49 168.1 0.1 2.8e-49 167.3 0.1 1.4 1 0 0 1 1 1 1 RIO1 family Rio2_N PF09202.11 OQR81317.1 - 1.9e-33 114.5 0.3 4.5e-33 113.3 0.3 1.7 1 0 0 1 1 1 1 Rio2, N-terminal APH PF01636.23 OQR81317.1 - 1.2e-07 31.9 3.8 0.0034 17.3 0.2 3.2 2 1 1 3 3 3 2 Phosphotransferase enzyme family Kdo PF06293.14 OQR81317.1 - 6.6e-06 25.6 0.2 0.0099 15.2 0.0 2.3 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 OQR81317.1 - 0.00016 21.1 0.0 0.00049 19.5 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Choline_kinase PF01633.20 OQR81317.1 - 0.016 14.8 1.2 0.47 10.0 0.1 2.3 2 0 0 2 2 2 0 Choline/ethanolamine kinase BUD22 PF09073.10 OQR81317.1 - 0.11 11.8 15.8 0.16 11.2 15.8 1.3 1 0 0 1 1 1 0 BUD22 Drc1-Sld2 PF11719.8 OQR81317.1 - 0.83 9.1 14.0 1.2 8.6 14.0 1.2 1 0 0 1 1 1 0 DNA replication and checkpoint protein DUF2457 PF10446.9 OQR81317.1 - 0.94 8.6 23.3 1.2 8.1 23.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Tub_N PF16322.5 OQR81317.1 - 1.6 9.1 12.0 2.3 8.6 12.0 1.2 1 0 0 1 1 1 0 Tubby N-terminal SAPS PF04499.15 OQR81317.1 - 1.9 7.2 9.8 2.6 6.7 9.8 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DNA_pol_phi PF04931.13 OQR81317.1 - 4.4 5.3 29.8 5.9 4.9 29.8 1.2 1 0 0 1 1 1 0 DNA polymerase phi Pro-kuma_activ PF09286.11 OQR81322.1 - 4.8e-16 59.4 0.0 8.1e-16 58.6 0.0 1.4 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain BROMI PF14961.6 OQR81324.1 - 2.2e-13 48.7 8.0 2.8e-13 48.3 8.0 1.1 1 0 0 1 1 1 1 Broad-minded protein Fer2_3 PF13085.6 OQR81325.1 - 3e-32 110.9 0.0 6e-32 109.9 0.0 1.5 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer4_17 PF13534.6 OQR81325.1 - 4.8e-10 39.8 5.9 4.8e-10 39.8 5.9 2.0 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_8 PF13183.6 OQR81325.1 - 2.5e-07 31.1 9.4 2.5e-07 31.1 9.4 2.7 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_10 PF13237.6 OQR81325.1 - 3.5e-07 30.2 4.3 3.5e-07 30.2 4.3 2.2 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer2 PF00111.27 OQR81325.1 - 0.00013 21.9 1.8 0.0025 17.7 0.3 2.4 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fer4_7 PF12838.7 OQR81325.1 - 0.038 14.6 8.8 0.038 14.6 8.8 2.5 2 2 0 2 2 2 0 4Fe-4S dicluster domain Fer4_18 PF13746.6 OQR81325.1 - 0.086 13.0 0.1 0.086 13.0 0.1 2.6 3 0 0 3 3 3 0 4Fe-4S dicluster domain SF3a60_bindingd PF12108.8 OQR81325.1 - 0.14 12.0 0.2 0.26 11.2 0.2 1.4 1 0 0 1 1 1 0 Splicing factor SF3a60 binding domain Fer4_9 PF13187.6 OQR81325.1 - 0.23 11.6 14.8 0.04 14.1 8.4 2.7 2 1 0 2 2 2 0 4Fe-4S dicluster domain C2 PF00168.30 OQR81326.1 - 6.8e-12 45.6 0.1 1.4e-11 44.6 0.1 1.5 1 0 0 1 1 1 1 C2 domain TUDOR_5 PF18359.1 OQR81326.1 - 8.3e-11 41.4 4.2 4.8e-05 23.0 1.2 2.5 2 0 0 2 2 2 2 Histone methyltransferase Tudor domain 1 53-BP1_Tudor PF09038.10 OQR81326.1 - 0.00048 20.1 0.4 0.28 11.1 0.1 2.5 2 0 0 2 2 2 2 Tumour suppressor p53-binding protein-1 Tudor DUF4537 PF15057.6 OQR81326.1 - 0.0079 16.2 0.1 0.041 13.9 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4537) Tudor_2 PF18104.1 OQR81326.1 - 0.042 13.5 3.6 2.6 7.8 0.3 2.8 3 0 0 3 3 3 0 Jumonji domain-containing protein 2A Tudor domain RNA_pol_Rpc82 PF05645.13 OQR81327.1 - 0.059 13.1 0.9 0.1 12.3 0.9 1.4 1 0 0 1 1 1 0 RNA polymerase III subunit RPC82 TPR_2 PF07719.17 OQR81328.1 - 5.6e-16 57.3 1.3 7.9e-05 22.5 0.1 4.0 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.28 OQR81328.1 - 6.7e-16 57.4 7.5 1.4e-06 27.8 0.1 4.0 4 0 0 4 4 3 3 Tetratricopeptide repeat TPR_8 PF13181.6 OQR81328.1 - 1.9e-08 33.9 3.3 0.0003 20.8 0.2 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_11 PF13414.6 OQR81328.1 - 4.1e-08 32.8 8.6 0.006 16.3 0.0 4.1 3 1 1 4 4 4 2 TPR repeat TPR_12 PF13424.6 OQR81328.1 - 2.4e-07 30.9 1.1 0.0016 18.7 0.2 3.0 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.6 OQR81328.1 - 1.8e-06 27.9 0.4 0.0039 17.5 0.1 3.1 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.6 OQR81328.1 - 8.2e-05 23.0 0.9 0.02 15.4 0.1 3.2 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 OQR81328.1 - 0.00091 19.9 2.1 0.12 13.3 0.1 3.8 3 1 1 4 4 3 1 Tetratricopeptide repeat IQ PF00612.27 OQR81328.1 - 0.0012 18.4 0.0 0.0012 18.4 0.0 2.3 3 0 0 3 3 2 1 IQ calmodulin-binding motif TPR_9 PF13371.6 OQR81328.1 - 0.0028 17.8 0.2 0.014 15.5 0.0 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat ApoO PF09769.9 OQR81328.1 - 0.011 15.7 6.7 0.016 15.2 1.1 3.0 3 0 0 3 3 3 0 Apolipoprotein O TPR_16 PF13432.6 OQR81328.1 - 0.013 16.1 0.4 0.79 10.4 0.0 2.8 2 1 0 2 2 2 0 Tetratricopeptide repeat ANAPC3 PF12895.7 OQR81328.1 - 0.016 15.4 4.5 0.51 10.6 3.4 2.7 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 OQR81328.1 - 0.073 13.7 0.2 3.8 8.3 0.1 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat Baculo_PEP_C PF04513.12 OQR81328.1 - 0.62 10.1 17.8 1.9 8.6 7.6 3.5 2 1 2 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus TPR_7 PF13176.6 OQR81328.1 - 2.3 8.4 5.5 50 4.3 0.0 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat BCDHK_Adom3 PF10436.9 OQR81328.1 - 2.4 8.0 16.8 0.56 10.0 11.8 2.4 2 1 0 2 2 2 0 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase TIG PF01833.24 OQR81329.1 - 3.3e-293 946.9 513.3 5.6e-12 45.6 0.3 65.9 65 1 0 65 65 65 53 IPT/TIG domain TIG_plexin PF17960.1 OQR81329.1 - 1e-39 134.4 110.2 0.073 13.1 0.0 39.9 47 0 0 47 47 47 18 TIG domain Laminin_G_3 PF13385.6 OQR81329.1 - 4.3e-26 91.9 1.9 1.7e-11 44.5 0.1 3.8 3 0 0 3 3 3 2 Concanavalin A-like lectin/glucanases superfamily Anth_Ig PF05587.13 OQR81329.1 - 0.026 14.8 36.5 2.3 8.6 0.1 14.7 17 0 0 17 17 17 0 Anthrax receptor extracellular domain DBB PF14545.6 OQR81329.1 - 3 7.8 16.6 32 4.4 0.0 9.2 11 0 0 11 11 11 0 Dof, BCAP, and BANK (DBB) motif, Tetraspanin PF00335.20 OQR81332.1 - 7.5e-07 29.1 54.7 0.00037 20.3 25.6 3.6 1 1 2 3 3 3 2 Tetraspanin family Pkinase PF00069.25 OQR81337.1 - 3.7e-51 174.0 0.0 5.6e-51 173.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQR81337.1 - 1.5e-48 165.3 0.0 2.2e-48 164.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase LRR_4 PF12799.7 OQR81337.1 - 3.2e-05 24.2 13.3 8.4e-05 22.9 1.8 4.3 4 0 0 4 4 4 1 Leucine Rich repeats (2 copies) Haspin_kinase PF12330.8 OQR81337.1 - 0.0046 15.9 0.1 0.025 13.5 0.0 2.1 2 2 0 2 2 2 1 Haspin like kinase domain Kdo PF06293.14 OQR81337.1 - 0.0085 15.5 0.0 0.016 14.6 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 OQR81337.1 - 0.012 14.4 0.1 0.019 13.8 0.1 1.1 1 0 0 1 1 1 0 Fungal protein kinase LRR_8 PF13855.6 OQR81337.1 - 0.013 15.2 2.2 0.013 15.2 2.2 2.7 2 0 0 2 2 2 0 Leucine rich repeat Kinase-like PF14531.6 OQR81337.1 - 0.038 13.3 0.0 0.064 12.6 0.0 1.3 1 0 0 1 1 1 0 Kinase-like LRR_1 PF00560.33 OQR81337.1 - 1.1 10.1 3.0 3.3e+02 2.5 0.1 4.6 4 0 0 4 4 4 0 Leucine Rich Repeat cNMP_binding PF00027.29 OQR81338.1 - 7.2e-37 125.3 0.2 3.7e-17 62.2 0.1 2.6 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain Ion_trans PF00520.31 OQR81338.1 - 1.9e-29 102.6 44.3 8e-15 54.7 18.8 2.6 2 1 0 2 2 2 2 Ion transport protein NDUFA12 PF05071.16 OQR81338.1 - 0.069 14.0 0.0 18 6.3 0.0 3.1 2 0 0 2 2 2 0 NADH ubiquinone oxidoreductase subunit NDUFA12 DUF2976 PF11190.8 OQR81338.1 - 0.074 12.9 4.5 0.9 9.4 0.1 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2976) DUF4179 PF13786.6 OQR81338.1 - 0.17 12.4 3.1 2.6 8.6 0.0 3.2 2 1 0 2 2 2 0 Domain of unknown function (DUF4179) cNMP_binding PF00027.29 OQR81339.1 - 1.1e-11 44.7 0.0 2.5e-11 43.5 0.0 1.7 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Ion_trans PF00520.31 OQR81339.1 - 4.2e-06 26.2 24.4 1.2e-05 24.7 24.4 1.7 1 1 0 1 1 1 1 Ion transport protein Sigma_reg_N PF13800.6 OQR81339.1 - 0.084 13.2 4.2 0.87 9.9 0.2 2.7 2 0 0 2 2 2 0 Sigma factor regulator N-terminal TMEM154 PF15102.6 OQR81340.1 - 0.029 14.3 0.3 0.12 12.3 0.4 2.0 2 0 0 2 2 2 0 TMEM154 protein family Caldesmon PF02029.15 OQR81340.1 - 0.1 11.3 21.0 0.14 10.9 21.0 1.1 1 0 0 1 1 1 0 Caldesmon DUF4876 PF16215.5 OQR81340.1 - 0.12 12.3 0.1 0.12 12.3 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4876) DUF4407 PF14362.6 OQR81340.1 - 0.31 10.3 11.6 0.64 9.3 11.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF948 PF06103.11 OQR81340.1 - 0.85 9.9 3.5 11 6.4 1.1 3.0 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) MscS_TM PF12794.7 OQR81340.1 - 0.88 8.4 5.7 2.2 7.1 2.6 2.3 2 0 0 2 2 2 0 Mechanosensitive ion channel inner membrane domain 1 Abhydrolase_1 PF00561.20 OQR81342.1 - 5.9e-14 52.3 0.0 1.7e-13 50.8 0.0 1.7 2 0 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 OQR81342.1 - 3.8e-07 29.6 0.0 7.2e-06 25.4 0.0 2.5 2 1 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 OQR81342.1 - 0.00059 20.5 0.0 0.0014 19.3 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family SSF PF00474.17 OQR81347.1 - 1.1e-26 93.6 19.9 1.1e-26 93.6 19.9 1.6 2 0 0 2 2 2 1 Sodium:solute symporter family COX16 PF14138.6 OQR81349.1 - 1.5e-14 54.3 1.9 1e-13 51.5 1.9 1.9 1 1 0 1 1 1 1 Cytochrome c oxidase assembly protein COX16 FAM178 PF14816.6 OQR81349.1 - 0.12 11.4 0.2 0.12 11.3 0.2 1.0 1 0 0 1 1 1 0 Family of unknown function, FAM178 Arc_PepC_II PF06847.11 OQR81349.1 - 0.23 12.0 3.1 0.89 10.1 0.2 2.1 1 1 1 2 2 2 0 Archaeal Peptidase A24 C-terminus Type II AIRC PF00731.20 OQR81350.1 - 9.7e-42 142.0 1.9 1.2e-41 141.7 1.9 1.1 1 0 0 1 1 1 1 AIR carboxylase Filamin PF00630.19 OQR81351.1 - 6.8e-16 59.0 0.2 1.3e-08 35.6 0.0 3.8 3 1 0 3 3 3 3 Filamin/ABP280 repeat Snf7 PF03357.21 OQR81352.1 - 2.4e-14 53.3 4.7 2.6e-14 53.2 4.7 1.0 1 0 0 1 1 1 1 Snf7 YlqD PF11068.8 OQR81352.1 - 0.003 17.9 4.1 0.0038 17.6 4.1 1.1 1 0 0 1 1 1 1 YlqD protein Prefoldin_2 PF01920.20 OQR81352.1 - 0.004 17.1 6.1 0.0051 16.8 0.4 2.0 1 1 1 2 2 2 1 Prefoldin subunit FapA PF03961.13 OQR81352.1 - 0.0065 15.1 2.0 0.0067 15.1 2.0 1.0 1 0 0 1 1 1 1 Flagellar Assembly Protein A ABC_tran_CTD PF16326.5 OQR81352.1 - 0.015 15.5 4.3 0.025 14.8 4.3 1.3 1 1 0 1 1 1 0 ABC transporter C-terminal domain DUF883 PF05957.13 OQR81352.1 - 0.042 14.4 1.7 0.056 14.1 1.7 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF883) ADIP PF11559.8 OQR81352.1 - 0.052 13.6 5.8 0.05 13.7 5.2 1.3 1 1 0 1 1 1 0 Afadin- and alpha -actinin-Binding SpoIISA_toxin PF14171.6 OQR81352.1 - 0.073 12.8 0.5 0.088 12.5 0.5 1.1 1 0 0 1 1 1 0 Toxin SpoIISA, type II toxin-antitoxin system ABC_tran PF00005.27 OQR81353.1 - 5.6e-23 82.0 0.0 8.3e-23 81.4 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 OQR81353.1 - 4.5e-07 30.0 2.1 0.018 14.9 0.1 2.3 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 OQR81353.1 - 0.00024 20.6 0.7 0.001 18.6 0.7 1.8 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 OQR81353.1 - 0.0033 17.2 0.1 0.011 15.5 0.0 1.8 2 1 0 2 2 2 1 AAA ATPase domain ABC_tran_Xtn PF12848.7 OQR81353.1 - 0.0094 16.0 0.3 0.032 14.2 0.3 1.9 1 0 0 1 1 1 1 ABC transporter AAA_29 PF13555.6 OQR81353.1 - 0.016 15.0 0.0 0.032 14.0 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF87 PF01935.17 OQR81353.1 - 0.047 13.8 0.6 0.45 10.6 0.0 2.3 2 0 0 2 2 2 0 Helicase HerA, central domain Rop PF01815.16 OQR81353.1 - 0.094 12.6 0.3 7.6 6.5 0.0 2.5 2 0 0 2 2 2 0 Rop protein MMR_HSR1 PF01926.23 OQR81353.1 - 0.13 12.3 0.0 0.42 10.7 0.0 1.9 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_23 PF13476.6 OQR81353.1 - 0.14 12.7 2.1 0.51 10.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain TMEM239 PF15841.5 OQR81354.1 - 0.0012 18.8 0.5 0.0059 16.5 0.0 2.2 2 0 0 2 2 2 1 Transmembrane protein 239 family LRR_6 PF13516.6 OQR81355.1 - 0.39 10.9 0.0 0.39 10.9 0.0 5.9 6 0 0 6 6 6 0 Leucine Rich repeat LRR_1 PF00560.33 OQR81355.1 - 4.8 8.1 7.9 1.1e+02 4.0 0.2 4.9 5 0 0 5 5 5 0 Leucine Rich Repeat Ldh_2 PF02615.14 OQR81356.1 - 2e-85 286.9 0.1 2.7e-85 286.5 0.1 1.2 1 0 0 1 1 1 1 Malate/L-lactate dehydrogenase DJ-1_PfpI PF01965.24 OQR81356.1 - 0.00042 20.1 0.1 0.0014 18.5 0.1 1.9 1 1 0 1 1 1 1 DJ-1/PfpI family GATase_5 PF13507.6 OQR81356.1 - 0.078 12.1 0.0 0.16 11.1 0.0 1.4 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain DHC_N2 PF08393.13 OQR81357.1 - 1e-06 28.2 0.1 1e-06 28.2 0.1 2.2 3 0 0 3 3 3 1 Dynein heavy chain, N-terminal region 2 DUF1765 PF08578.10 OQR81358.1 - 3.3e-17 63.1 2.5 3.3e-17 63.1 2.5 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF1765) Pkinase PF00069.25 OQR81359.1 - 5.9e-71 238.9 0.0 7.6e-71 238.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQR81359.1 - 8.3e-34 117.0 0.0 1.2e-33 116.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.24 OQR81359.1 - 6.3e-08 33.2 3.4 4.7e-06 27.2 0.7 2.8 2 0 0 2 2 2 2 Protein kinase C terminal domain PX PF00787.24 OQR81359.1 - 8.3e-08 32.2 0.3 1.6e-07 31.3 0.3 1.5 1 0 0 1 1 1 1 PX domain Kinase-like PF14531.6 OQR81359.1 - 0.0029 17.0 0.0 0.031 13.6 0.0 2.2 2 0 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 OQR81359.1 - 0.07 12.1 0.0 0.099 11.6 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain CCDC23 PF15674.5 OQR81361.1 - 0.011 15.8 2.5 0.026 14.5 2.5 1.6 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 23 LMBR1 PF04791.16 OQR81361.1 - 0.012 14.6 2.7 0.016 14.2 2.7 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Rbsn PF11464.8 OQR81361.1 - 0.021 14.5 2.2 0.058 13.1 2.2 1.7 1 0 0 1 1 1 0 Rabenosyn Rab binding domain Speriolin_N PF15058.6 OQR81361.1 - 0.051 13.7 0.1 0.15 12.2 0.2 1.7 2 0 0 2 2 2 0 Speriolin N terminus DASH_Dam1 PF08653.10 OQR81361.1 - 0.34 10.7 1.5 1 9.2 0.5 2.1 2 0 0 2 2 2 0 DASH complex subunit Dam1 CCDC-167 PF15188.6 OQR81361.1 - 0.53 10.7 8.0 0.16 12.4 1.1 2.4 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 HR1 PF02185.16 OQR81361.1 - 1.3 9.2 7.8 0.33 11.1 3.6 2.2 2 0 0 2 2 2 0 Hr1 repeat bZIP_Maf PF03131.17 OQR81361.1 - 1.4 9.4 7.8 0.19 12.2 2.6 2.0 2 0 0 2 2 2 0 bZIP Maf transcription factor Csm1_N PF18504.1 OQR81361.1 - 4.5 7.7 8.9 15 6.0 2.9 2.5 2 0 0 2 2 2 0 Csm1 N-terminal domain Asp-B-Hydro_N PF05279.11 OQR81362.1 - 0.077 13.1 0.8 0.11 12.5 0.8 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region CCDC23 PF15674.5 OQR81362.1 - 3.5 7.7 12.4 0.28 11.2 4.8 2.2 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 23 Macoilin PF09726.9 OQR81362.1 - 5.6 5.4 10.6 7.8 4.9 10.6 1.1 1 0 0 1 1 1 0 Macoilin family RGS PF00615.19 OQR81363.1 - 0.00015 22.0 0.0 0.00029 21.1 0.0 1.4 1 0 0 1 1 1 1 Regulator of G protein signaling domain Ricin_B_lectin PF00652.22 OQR81365.1 - 7.1e-22 78.0 12.1 3e-14 53.4 4.5 2.2 2 0 0 2 2 2 2 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.6 OQR81365.1 - 2.1e-09 37.9 10.7 0.00062 20.4 1.3 3.5 2 1 1 3 3 3 3 Ricin-type beta-trefoil lectin domain-like 2-Hacid_dh_C PF02826.19 OQR81366.1 - 1.5e-55 187.3 0.0 4.6e-55 185.7 0.0 1.8 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 OQR81366.1 - 1.3e-25 89.6 0.0 1.5e-25 89.4 0.0 1.0 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 OQR81366.1 - 4.9e-05 23.5 0.2 0.0004 20.6 0.1 2.1 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase IlvN PF07991.12 OQR81366.1 - 0.00062 19.4 0.0 0.0051 16.4 0.0 2.0 2 0 0 2 2 2 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain AdoHcyase_NAD PF00670.21 OQR81366.1 - 0.0038 17.3 0.9 0.0088 16.1 0.9 1.5 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain CoA_binding_2 PF13380.6 OQR81366.1 - 0.0069 16.9 0.0 0.016 15.7 0.0 1.6 1 0 0 1 1 1 1 CoA binding domain F420_oxidored PF03807.17 OQR81366.1 - 0.052 14.1 0.2 1.7 9.3 0.1 2.6 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent 3HCDH_N PF02737.18 OQR81366.1 - 0.066 13.1 0.3 0.14 12.1 0.3 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Rossmann-like PF10727.9 OQR81366.1 - 0.13 12.1 0.1 0.47 10.3 0.0 1.9 2 0 0 2 2 2 0 Rossmann-like domain FA_FANCE PF11510.8 OQR81367.1 - 3.2e-08 33.2 8.1 5.3e-08 32.5 8.1 1.3 1 0 0 1 1 1 1 Fanconi Anaemia group E protein FANCE Ank_2 PF12796.7 OQR81369.1 - 1.6e-60 201.7 6.6 2e-15 57.1 0.1 6.3 3 3 4 7 7 7 7 Ankyrin repeats (3 copies) Ank PF00023.30 OQR81369.1 - 5.8e-49 162.5 15.4 8.3e-07 29.2 0.3 9.8 9 1 1 10 10 10 9 Ankyrin repeat Ank_4 PF13637.6 OQR81369.1 - 9.9e-49 163.1 3.3 5.4e-10 39.6 0.1 9.3 4 3 6 10 10 10 9 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQR81369.1 - 3e-39 128.5 1.1 0.00015 21.9 0.0 10.8 11 0 0 11 11 11 8 Ankyrin repeat Ank_5 PF13857.6 OQR81369.1 - 1.4e-31 108.1 7.7 3.6e-06 27.1 0.1 8.2 5 1 3 8 8 8 7 Ankyrin repeats (many copies) MnmE_helical PF12631.7 OQR81370.1 - 5.5e-51 173.7 3.5 6.7e-51 173.4 3.5 1.1 1 0 0 1 1 1 1 MnmE helical domain TrmE_N PF10396.9 OQR81370.1 - 2.8e-36 124.3 0.0 7.7e-36 122.9 0.0 1.8 1 0 0 1 1 1 1 GTP-binding protein TrmE N-terminus MMR_HSR1 PF01926.23 OQR81370.1 - 2.4e-21 76.0 0.6 5.4e-21 74.8 0.2 1.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 OQR81370.1 - 5.7e-09 35.7 0.2 9.5e-09 35.0 0.2 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 OQR81370.1 - 2.9e-05 24.2 0.0 7.4e-05 22.9 0.0 1.6 1 1 0 1 1 1 1 Dynamin family MMR_HSR1_Xtn PF16897.5 OQR81370.1 - 0.0002 21.4 2.0 0.0002 21.3 0.2 2.0 2 0 0 2 2 2 1 C-terminal region of MMR_HSR1 domain RsgA_GTPase PF03193.16 OQR81370.1 - 0.00036 20.5 0.4 0.32 10.9 0.0 2.7 2 1 0 2 2 2 2 RsgA GTPase Arf PF00025.21 OQR81370.1 - 0.00042 19.8 0.4 0.34 10.3 0.0 2.5 2 0 0 2 2 2 2 ADP-ribosylation factor family ABC_tran PF00005.27 OQR81370.1 - 0.0028 18.1 1.0 0.012 16.1 0.4 2.3 2 1 1 3 3 3 1 ABC transporter cobW PF02492.19 OQR81370.1 - 0.0067 16.0 0.4 0.092 12.3 0.5 2.2 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_28 PF13521.6 OQR81370.1 - 0.016 15.5 0.0 0.035 14.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain DUF2188 PF09954.9 OQR81371.1 - 0.55 10.4 5.0 4.4 7.5 0.2 3.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2188) Pox_A_type_inc PF04508.12 OQR81371.1 - 4.5 7.3 12.2 60 3.7 0.0 5.6 5 0 0 5 5 5 0 Viral A-type inclusion protein repeat zf-met PF12874.7 OQR81372.1 - 5.9e-07 29.7 0.1 1e-06 28.9 0.1 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type SURF2 PF05477.11 OQR81372.1 - 1.3e-06 28.3 1.8 1.8e-06 27.9 1.8 1.2 1 0 0 1 1 1 1 Surfeit locus protein 2 (SURF2) zf-C2H2_jaz PF12171.8 OQR81372.1 - 7.8e-06 26.0 0.0 1.4e-05 25.2 0.0 1.4 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding SNRNP27 PF08648.12 OQR81372.1 - 2.3e-05 24.4 2.2 2.3e-05 24.4 2.2 2.4 2 0 0 2 2 2 1 U4/U6.U5 small nuclear ribonucleoproteins Vfa1 PF08432.10 OQR81372.1 - 0.019 15.3 2.7 0.037 14.4 2.7 1.4 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 zf-U1 PF06220.12 OQR81372.1 - 0.033 13.9 0.0 0.057 13.2 0.0 1.3 1 0 0 1 1 1 0 U1 zinc finger zf-C2H2_2 PF12756.7 OQR81372.1 - 0.09 13.1 0.2 0.21 11.9 0.0 1.6 1 1 0 1 1 1 0 C2H2 type zinc-finger (2 copies) zf-DBF PF07535.12 OQR81372.1 - 0.13 12.4 0.0 0.26 11.4 0.0 1.4 1 0 0 1 1 1 0 DBF zinc finger GAF PF01590.26 OQR81373.1 - 9.8e-28 97.4 0.1 3.4e-15 56.8 0.0 2.4 2 0 0 2 2 2 2 GAF domain PDEase_I PF00233.19 OQR81373.1 - 7e-21 75.0 0.1 1.8e-20 73.7 0.1 1.7 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase GAF_2 PF13185.6 OQR81373.1 - 2.5e-16 60.2 0.0 6e-09 36.3 0.0 2.3 2 0 0 2 2 2 2 GAF domain GAF_3 PF13492.6 OQR81373.1 - 8.8e-05 22.9 0.0 0.45 10.9 0.0 2.9 2 1 0 2 2 2 2 GAF domain Flavi_capsid PF01003.19 OQR81373.1 - 0.092 12.5 0.1 0.17 11.6 0.1 1.4 1 0 0 1 1 1 0 Flavivirus capsid protein C PDEase_I PF00233.19 OQR81374.1 - 4.9e-63 213.0 13.1 1.2e-62 211.8 11.8 2.1 2 0 0 2 2 2 1 3'5'-cyclic nucleotide phosphodiesterase GAF_2 PF13185.6 OQR81374.1 - 6.2e-40 136.7 0.0 7.7e-11 42.5 0.0 4.3 4 0 0 4 4 4 4 GAF domain GAF PF01590.26 OQR81374.1 - 1.2e-39 135.9 3.3 1.8e-11 44.8 0.1 4.6 4 0 0 4 4 4 4 GAF domain GAF_3 PF13492.6 OQR81374.1 - 1.8e-24 86.6 0.1 6.6e-08 33.0 0.0 4.9 5 0 0 5 5 5 4 GAF domain PA PF02225.22 OQR81375.1 - 9.8e-14 51.2 0.0 1.3e-13 50.8 0.0 1.3 1 0 0 1 1 1 1 PA domain Corona_S1 PF01600.16 OQR81375.1 - 0.005 15.7 0.0 0.0065 15.3 0.0 1.1 1 0 0 1 1 1 1 Coronavirus S1 glycoprotein AA_kinase PF00696.28 OQR81377.1 - 1.6e-38 132.6 0.0 2.4e-38 132.1 0.0 1.3 1 0 0 1 1 1 1 Amino acid kinase family ChuX_HutX PF06228.13 OQR81377.1 - 0.054 13.3 0.0 1 9.1 0.0 2.7 3 0 0 3 3 3 0 Haem utilisation ChuX/HutX Proteasome PF00227.26 OQR81378.1 - 8.8e-31 106.9 0.0 1.1e-30 106.6 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 OQR81378.1 - 3.7e-14 52.1 0.0 5.9e-14 51.4 0.0 1.3 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature DEAD PF00270.29 OQR81380.1 - 9.8e-32 110.1 0.0 1.2e-31 109.9 0.0 1.0 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 OQR81380.1 - 0.0059 16.6 0.0 0.0071 16.4 0.0 1.1 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF2477 PF10631.9 OQR81380.1 - 0.083 13.6 0.1 0.11 13.1 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2477) DEAD PF00270.29 OQR81381.1 - 1.7e-10 41.0 0.0 1.9e-10 40.8 0.0 1.1 1 0 0 1 1 1 1 DEAD/DEAH box helicase MORN PF02493.20 OQR81382.1 - 1.6e-90 291.9 125.7 5.7e-06 25.9 0.3 25.2 25 0 0 25 25 25 21 MORN repeat Avl9 PF09794.9 OQR81382.1 - 2.6e-21 75.8 0.1 1.3e-09 37.3 0.1 2.1 1 1 1 2 2 2 2 Transport protein Avl9 SPA PF08616.10 OQR81382.1 - 2.2e-05 24.4 0.1 5.7e-05 23.0 0.1 1.6 1 1 0 1 1 1 1 Stabilization of polarity axis ubiquitin PF00240.23 OQR81384.1 - 1.1e-33 114.8 0.4 1.1e-33 114.8 0.4 1.6 2 0 0 2 2 2 1 Ubiquitin family Ribosomal_S27 PF01599.19 OQR81384.1 - 1.2e-26 92.6 3.3 1.2e-26 92.6 3.3 1.8 2 0 0 2 2 2 1 Ribosomal protein S27a Rad60-SLD PF11976.8 OQR81384.1 - 1.9e-15 56.5 0.7 1.9e-15 56.5 0.7 1.7 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 OQR81384.1 - 1.7e-05 25.2 0.3 0.00013 22.4 0.1 2.3 2 1 0 2 2 2 1 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 OQR81384.1 - 0.00038 20.5 0.4 0.00086 19.4 0.4 1.7 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_5 PF18037.1 OQR81384.1 - 0.0044 17.4 1.1 0.017 15.5 0.0 2.1 1 1 0 2 2 2 1 Ubiquitin-like domain DUF2407 PF10302.9 OQR81384.1 - 0.01 16.4 0.5 0.014 15.9 0.5 1.2 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain TBK1_ULD PF18396.1 OQR81384.1 - 0.011 15.6 0.0 0.017 15.1 0.0 1.3 1 0 0 1 1 1 0 TANK binding kinase 1 ubiquitin-like domain IBR PF01485.21 OQR81384.1 - 0.022 15.0 0.7 0.036 14.3 0.7 1.4 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain PKD_channel PF08016.12 OQR81385.1 - 1.2e-45 155.9 13.0 1.2e-45 155.9 13.0 1.9 2 1 0 2 2 2 1 Polycystin cation channel Ion_trans PF00520.31 OQR81385.1 - 4e-09 36.1 20.1 4e-09 36.1 20.1 2.1 2 0 0 2 2 2 1 Ion transport protein DUF3278 PF11683.8 OQR81385.1 - 4 7.5 12.5 0.098 12.7 1.8 3.2 3 1 0 3 3 3 0 Protein of unknown function (DUF3278) IFT57 PF10498.9 OQR81386.1 - 0.00024 20.2 9.8 0.00024 20.2 9.8 7.2 3 1 5 8 8 8 2 Intra-flagellar transport protein 57 HAP1_N PF04849.13 OQR81386.1 - 0.00091 18.5 6.3 0.00091 18.5 6.3 8.2 3 2 5 8 8 8 2 HAP1 N-terminal conserved region DUF1811 PF08838.10 OQR81386.1 - 0.0022 18.2 0.6 0.0022 18.2 0.6 6.8 6 3 2 8 8 8 2 Protein of unknown function (DUF1811) LigT_PEase PF02834.16 OQR81386.1 - 0.015 15.5 0.1 0.015 15.5 0.1 4.7 5 0 0 5 5 5 0 LigT like Phosphoesterase Myb_DNA-bind_4 PF13837.6 OQR81386.1 - 0.15 12.4 5.6 3 8.3 0.1 4.3 3 0 0 3 3 3 0 Myb/SANT-like DNA-binding domain Scs3p PF10261.9 OQR81387.1 - 0.00012 21.6 1.0 0.00016 21.3 1.0 1.2 1 0 0 1 1 1 1 Inositol phospholipid synthesis and fat-storage-inducing TM ABC2_membrane_2 PF12679.7 OQR81387.1 - 0.036 13.3 0.3 0.11 11.7 0.3 1.7 1 1 0 1 1 1 0 ABC-2 family transporter protein DUF2663 PF10864.8 OQR81387.1 - 0.1 13.0 2.2 0.15 12.4 0.6 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2663) PI3Ka PF00613.20 OQR81388.1 - 1.6e-45 154.8 1.7 3e-45 153.9 1.7 1.4 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3K_C2 PF00792.24 OQR81388.1 - 6.7e-26 90.9 0.0 1.2e-25 90.0 0.0 1.5 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 PI3_PI4_kinase PF00454.27 OQR81388.1 - 1.7e-11 44.5 0.0 3.1e-11 43.6 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FYVE PF01363.21 OQR81389.1 - 9.3e-19 67.3 11.1 1.9e-18 66.4 11.1 1.5 1 0 0 1 1 1 1 FYVE zinc finger GAF PF01590.26 OQR81389.1 - 2.3e-05 25.0 0.0 6.7e-05 23.5 0.0 1.7 2 0 0 2 2 2 1 GAF domain GAF_2 PF13185.6 OQR81389.1 - 0.0072 16.6 0.0 0.017 15.4 0.0 1.6 2 0 0 2 2 2 1 GAF domain C1_2 PF03107.16 OQR81389.1 - 0.15 12.4 6.0 0.49 10.8 6.0 1.9 1 0 0 1 1 1 0 C1 domain FYVE_2 PF02318.16 OQR81389.1 - 0.28 11.4 5.9 0.55 10.5 5.9 1.4 1 0 0 1 1 1 0 FYVE-type zinc finger PIP5K PF01504.18 OQR81390.1 - 2.5e-71 240.1 0.6 2.1e-70 237.1 0.6 2.0 1 1 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase He_PIG PF05345.12 OQR81392.1 - 0.18 12.0 3.2 0.4 10.9 0.9 2.6 2 0 0 2 2 2 0 Putative Ig domain DIRP PF06584.13 OQR81394.1 - 3e-24 85.2 1.1 6.6e-24 84.1 0.3 2.0 2 0 0 2 2 2 1 DIRP CREPT PF16566.5 OQR81394.1 - 0.047 13.9 1.3 0.15 12.2 0.3 2.4 2 0 0 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour HEAT_PBS PF03130.16 OQR81394.1 - 0.18 12.6 0.8 9 7.3 0.1 3.2 3 0 0 3 3 3 0 PBS lyase HEAT-like repeat Acid_phosphat_B PF03767.14 OQR81395.1 - 0.17 11.4 0.1 0.5 9.9 0.0 1.7 2 0 0 2 2 2 0 HAD superfamily, subfamily IIIB (Acid phosphatase) Prenyltransf PF01255.19 OQR81396.1 - 7.7e-75 251.3 0.0 9.2e-75 251.0 0.0 1.1 1 0 0 1 1 1 1 Putative undecaprenyl diphosphate synthase Swi3 PF07962.12 OQR81396.1 - 0.0031 17.5 0.0 2.7 8.1 0.0 2.4 2 0 0 2 2 2 2 Replication Fork Protection Component Swi3 Cid2 PF09774.9 OQR81396.1 - 0.075 13.5 0.0 0.1 13.0 0.0 1.2 1 0 0 1 1 1 0 Caffeine-induced death protein 2 RuBisCO_large PF00016.20 OQR81396.1 - 0.093 11.9 0.0 0.14 11.3 0.0 1.2 1 0 0 1 1 1 0 Ribulose bisphosphate carboxylase large chain, catalytic domain DIOX_N PF14226.6 OQR81397.1 - 5.6e-27 94.8 0.0 8.4e-27 94.3 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 OQR81397.1 - 3.1e-22 78.9 0.0 6e-22 78.0 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Pro_isomerase PF00160.21 OQR81398.1 - 2.7e-39 135.0 0.0 3.4e-39 134.7 0.0 1.2 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD ABC_tran PF00005.27 OQR81399.1 - 5.2e-53 179.2 0.0 1.3e-26 93.7 0.0 2.7 2 0 0 2 2 2 2 ABC transporter ABC2_membrane_3 PF12698.7 OQR81399.1 - 8.4e-46 156.7 72.8 2.7e-33 115.5 21.0 3.0 3 1 0 3 3 3 2 ABC-2 family transporter protein AAA_21 PF13304.6 OQR81399.1 - 1e-19 71.5 2.3 4e-06 26.9 0.0 4.1 4 0 0 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 OQR81399.1 - 4.4e-05 23.4 0.3 0.12 12.1 0.0 2.8 3 0 0 3 3 3 2 AAA ATPase domain AAA_23 PF13476.6 OQR81399.1 - 6.7e-05 23.5 1.6 0.0019 18.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain SMC_N PF02463.19 OQR81399.1 - 7e-05 22.4 0.1 0.87 9.0 0.0 3.3 3 0 0 3 3 3 2 RecF/RecN/SMC N terminal domain SbcCD_C PF13558.6 OQR81399.1 - 0.00069 19.8 0.0 0.38 11.0 0.0 3.5 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit RsgA_GTPase PF03193.16 OQR81399.1 - 0.0016 18.3 0.3 0.016 15.1 0.1 2.3 2 0 0 2 2 2 1 RsgA GTPase AAA_29 PF13555.6 OQR81399.1 - 0.002 17.9 0.9 0.012 15.4 0.1 2.4 2 0 0 2 2 2 1 P-loop containing region of AAA domain DUF4162 PF13732.6 OQR81399.1 - 0.0038 17.9 0.8 0.94 10.2 0.0 4.0 4 0 0 4 4 4 1 Domain of unknown function (DUF4162) AAA_30 PF13604.6 OQR81399.1 - 0.011 15.5 0.1 1.7 8.3 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 OQR81399.1 - 0.025 15.0 0.0 7.5 6.9 0.0 2.7 2 0 0 2 2 2 0 AAA ATPase domain MukB PF04310.12 OQR81399.1 - 0.041 13.7 1.9 1.6 8.4 0.1 2.5 2 0 0 2 2 2 0 MukB N-terminal MMR_HSR1 PF01926.23 OQR81399.1 - 0.092 12.8 0.0 2.9 8.0 0.0 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase HTH_5 PF01022.20 OQR81399.1 - 0.11 12.4 0.3 0.29 11.0 0.3 1.8 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family AAA PF00004.29 OQR81399.1 - 0.14 12.6 1.4 55 4.2 0.0 3.5 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 OQR81399.1 - 0.21 11.3 1.2 5.8 6.6 0.0 2.7 2 0 0 2 2 2 0 AAA domain SRP54 PF00448.22 OQR81399.1 - 0.52 9.9 4.0 10 5.7 0.1 2.3 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain VPS13_C PF16909.5 OQR81400.1 - 2.3e-46 157.8 3.5 4.5e-41 140.6 0.1 2.9 2 0 0 2 2 2 2 Vacuolar-sorting-associated 13 protein C-terminal Chorein_N PF12624.7 OQR81400.1 - 2.6e-19 69.4 0.6 1.2e-18 67.4 0.0 2.5 3 0 0 3 3 3 1 N-terminal region of Chorein or VPS13 SHR-BD PF06650.12 OQR81400.1 - 2.7e-16 59.7 0.1 1.3e-12 47.7 0.0 3.0 2 0 0 2 2 2 2 SHR-binding domain of vacuolar-sorting associated protein 13 C2 PF00168.30 OQR81400.1 - 3.3e-09 36.9 0.1 1.2e-06 28.8 0.0 3.7 3 0 0 3 3 3 1 C2 domain ATG_C PF09333.11 OQR81400.1 - 0.0044 17.3 0.0 0.013 15.9 0.0 1.7 1 0 0 1 1 1 1 Autophagy-related protein C terminal domain VPS13 PF16908.5 OQR81400.1 - 0.019 14.8 5.8 1.5 8.6 0.1 3.5 2 1 0 3 3 3 0 Vacuolar sorting-associated protein 13, N-terminal Pro_CA PF00484.19 OQR81401.1 - 3.3e-49 167.2 0.1 5.5e-49 166.5 0.1 1.4 1 0 0 1 1 1 1 Carbonic anhydrase NAD_Gly3P_dh_N PF01210.23 OQR81401.1 - 4e-40 137.4 0.0 8.9e-40 136.2 0.0 1.6 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_Gly3P_dh_C PF07479.14 OQR81401.1 - 1.7e-38 132.1 0.4 4.7e-38 130.7 0.1 1.9 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus F420_oxidored PF03807.17 OQR81401.1 - 2.1e-12 47.4 0.1 7.9e-12 45.6 0.0 2.0 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent ApbA PF02558.16 OQR81401.1 - 2.1e-09 37.2 0.0 3.9e-09 36.3 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA NAD_binding_2 PF03446.15 OQR81401.1 - 2.3e-09 37.6 0.0 4.4e-09 36.7 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 3HCDH_N PF02737.18 OQR81401.1 - 7.6e-06 25.9 0.1 2e-05 24.6 0.1 1.8 1 1 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 OQR81401.1 - 2.8e-05 23.5 0.1 0.00095 18.5 0.0 2.3 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 OQR81401.1 - 0.0011 18.3 0.0 0.0074 15.7 0.0 2.1 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_10 PF13460.6 OQR81401.1 - 0.0051 16.7 0.0 0.051 13.5 0.0 2.3 2 0 0 2 2 2 1 NAD(P)H-binding UDPG_MGDP_dh_N PF03721.14 OQR81401.1 - 0.0093 15.6 0.0 0.019 14.5 0.0 1.6 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain GFO_IDH_MocA PF01408.22 OQR81401.1 - 0.012 16.4 0.2 0.07 14.0 0.1 2.3 2 0 0 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold Sacchrp_dh_NADP PF03435.18 OQR81401.1 - 0.025 14.9 0.0 0.58 10.4 0.0 2.7 2 1 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain IlvN PF07991.12 OQR81401.1 - 0.025 14.2 0.7 0.32 10.5 0.2 2.8 2 1 0 2 2 2 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain OCD_Mu_crystall PF02423.15 OQR81401.1 - 0.072 12.0 0.0 0.16 10.9 0.0 1.6 2 0 0 2 2 2 0 Ornithine cyclodeaminase/mu-crystallin family PDH PF02153.17 OQR81401.1 - 0.077 12.0 0.2 0.18 10.8 0.1 1.5 2 0 0 2 2 2 0 Prephenate dehydrogenase Shikimate_DH PF01488.20 OQR81401.1 - 0.092 12.8 0.0 3 7.9 0.0 2.8 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase Pyr_redox_2 PF07992.14 OQR81401.1 - 0.14 11.3 0.0 1.6 7.9 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Ank_2 PF12796.7 OQR81402.1 - 4e-19 69.0 0.1 2.5e-12 47.2 0.0 3.3 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OQR81402.1 - 4e-19 66.7 0.4 0.021 15.3 0.0 5.6 5 0 0 5 5 5 5 Ankyrin repeat Ank PF00023.30 OQR81402.1 - 7.4e-18 64.1 1.6 4.4e-05 23.7 0.1 5.6 5 0 0 5 5 5 4 Ankyrin repeat FYVE PF01363.21 OQR81402.1 - 2.5e-17 62.8 8.5 3.9e-17 62.2 8.5 1.3 1 0 0 1 1 1 1 FYVE zinc finger Ank_5 PF13857.6 OQR81402.1 - 4.4e-17 61.9 3.2 3.5e-05 24.0 0.1 4.7 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 OQR81402.1 - 1.8e-12 47.5 2.0 4.7e-06 27.0 0.0 5.7 3 2 4 7 7 7 2 Ankyrin repeats (many copies) tRNA_edit PF04073.15 OQR81403.1 - 1.2e-07 31.8 0.1 7.4e-07 29.3 0.1 1.9 1 1 0 1 1 1 1 Aminoacyl-tRNA editing domain DUF5607 PF18355.1 OQR81404.1 - 0.19 12.2 0.0 0.35 11.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5607) Glycos_transf_1 PF00534.20 OQR81405.1 - 5.8e-05 22.7 0.0 0.0001 21.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 OQR81405.1 - 0.0011 19.4 0.0 0.0022 18.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 C2 PF00168.30 OQR81406.1 - 0.014 15.7 0.3 1.3 9.3 0.0 3.3 3 0 0 3 3 3 0 C2 domain Tyr_Deacylase PF02580.16 OQR81407.1 - 2e-26 93.2 0.0 2.4e-26 93.0 0.0 1.1 1 0 0 1 1 1 1 D-Tyr-tRNA(Tyr) deacylase FTR1 PF03239.14 OQR81409.1 - 0.18 11.0 0.0 0.31 10.2 0.0 1.3 1 0 0 1 1 1 0 Iron permease FTR1 family cNMP_binding PF00027.29 OQR81410.1 - 3.2e-56 187.4 0.9 2.3e-14 53.2 0.0 4.5 4 0 0 4 4 4 4 Cyclic nucleotide-binding domain Ion_trans PF00520.31 OQR81410.1 - 1.1e-29 103.4 80.6 1.1e-13 51.0 13.1 4.5 4 0 0 4 4 4 4 Ion transport protein zf-B_box PF00643.24 OQR81410.1 - 0.035 14.3 10.7 0.085 13.0 10.7 1.7 1 0 0 1 1 1 0 B-box zinc finger IBR PF01485.21 OQR81410.1 - 0.95 9.7 5.5 2.5 8.4 5.5 1.7 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain GTP_EFTU PF00009.27 OQR81411.1 - 2.5e-36 125.0 0.6 8.1e-36 123.4 0.0 2.2 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain IF-2 PF11987.8 OQR81411.1 - 5.7e-19 68.2 0.0 2.1e-18 66.3 0.0 2.1 1 0 0 1 1 1 1 Translation-initiation factor 2 GTP_EFTU_D4 PF14578.6 OQR81411.1 - 2.6e-15 56.1 1.4 4.5e-15 55.3 0.1 2.2 2 0 0 2 2 2 1 Elongation factor Tu domain 4 GTP_EFTU_D2 PF03144.25 OQR81411.1 - 1.7e-10 41.1 7.0 6.4e-06 26.5 0.4 3.5 3 0 0 3 3 3 2 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 OQR81411.1 - 8.8e-07 29.0 0.1 6.2e-06 26.3 0.0 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase Roc PF08477.13 OQR81411.1 - 0.00087 19.5 0.0 0.0024 18.1 0.0 1.8 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase ATP_bind_1 PF03029.17 OQR81411.1 - 0.0029 17.4 0.1 0.021 14.6 0.0 2.6 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein AAA_22 PF13401.6 OQR81411.1 - 0.031 14.6 2.1 0.054 13.8 0.1 2.5 2 1 0 2 2 2 0 AAA domain Ras PF00071.22 OQR81411.1 - 0.056 13.0 0.0 0.26 10.9 0.0 2.2 1 1 0 1 1 1 0 Ras family Helitron_like_N PF14214.6 OQR81411.1 - 0.097 12.9 1.9 0.27 11.4 1.9 1.8 1 0 0 1 1 1 0 Helitron helicase-like domain at N-terminus RRM_1 PF00076.22 OQR81412.1 - 2.4e-17 62.5 0.1 3.9e-17 61.8 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FoP_duplication PF13865.6 OQR81412.1 - 2.8e-05 24.6 8.7 2.8e-05 24.6 8.7 3.6 3 2 1 4 4 4 1 C-terminal duplication domain of Friend of PRMT1 RRM_3 PF08777.11 OQR81412.1 - 0.077 13.1 0.2 0.14 12.3 0.2 1.4 1 0 0 1 1 1 0 RNA binding motif fn3 PF00041.21 OQR81413.1 - 2.4e-28 98.3 36.9 0.0019 18.5 0.1 14.3 14 0 0 14 14 14 10 Fibronectin type III domain Membrane_bind PF14564.6 OQR81413.1 - 0.0033 17.9 0.0 0.022 15.2 0.0 2.5 1 0 0 1 1 1 1 Membrane binding PP28 PF10252.9 OQR81414.1 - 2.1e-20 73.0 19.9 2.1e-20 73.0 19.9 2.9 2 1 1 3 3 3 1 Casein kinase substrate phosphoprotein PP28 SAP PF02037.27 OQR81414.1 - 1.7e-10 40.4 2.0 6.9e-10 38.5 0.3 2.3 2 0 0 2 2 2 1 SAP domain Ank_2 PF12796.7 OQR81415.1 - 5.8e-39 132.6 2.4 1e-15 58.1 0.1 3.3 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQR81415.1 - 1.7e-32 111.4 0.1 1.1e-12 48.2 0.0 4.5 1 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQR81415.1 - 1.8e-27 92.3 1.6 0.00063 20.0 0.0 6.8 5 1 2 7 7 7 5 Ankyrin repeat Ank_5 PF13857.6 OQR81415.1 - 3e-26 91.1 2.2 2.3e-07 31.0 0.0 5.8 1 1 5 6 6 6 5 Ankyrin repeats (many copies) Ank PF00023.30 OQR81415.1 - 6e-25 86.5 0.4 0.0028 18.0 0.0 6.3 5 1 1 6 6 6 5 Ankyrin repeat PX PF00787.24 OQR81415.1 - 8.4e-16 58.0 0.1 2.2e-15 56.6 0.1 1.7 1 0 0 1 1 1 1 PX domain MycE_N PF17843.1 OQR81415.1 - 0.15 12.5 0.9 0.75 10.3 0.1 2.3 2 0 0 2 2 2 0 MycE methyltransferase N-terminal NUDIX PF00293.28 OQR81416.1 - 6.5e-16 58.6 0.0 9.6e-16 58.0 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain zf-C3HC4_2 PF13923.6 OQR81416.1 - 1.8e-11 43.6 9.4 3.1e-11 42.9 9.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 OQR81416.1 - 5.2e-10 39.0 5.7 8.4e-10 38.4 5.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 OQR81416.1 - 2.2e-09 37.5 10.9 3.5e-09 36.8 10.9 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 OQR81416.1 - 2.6e-09 36.8 9.1 4.3e-09 36.1 9.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OQR81416.1 - 4.8e-07 29.7 7.1 7.4e-06 25.9 8.1 2.2 1 1 1 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 OQR81416.1 - 4.8e-07 29.6 7.0 7.9e-07 28.9 7.0 1.4 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 OQR81416.1 - 5e-06 26.3 7.1 7.9e-06 25.6 7.1 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 OQR81416.1 - 5.8e-05 23.2 10.4 0.00011 22.3 10.4 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.7 OQR81416.1 - 0.0024 18.1 8.6 0.0047 17.2 8.6 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain DUF3659 PF12396.8 OQR81416.1 - 0.13 12.2 0.1 0.24 11.3 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3659) zf-RING_11 PF17123.5 OQR81416.1 - 0.19 11.5 5.2 0.2 11.4 2.4 2.2 2 0 0 2 2 2 0 RING-like zinc finger Baculo_IE-1 PF05290.11 OQR81416.1 - 0.29 11.1 5.5 0.56 10.2 5.5 1.4 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) zf-RING_4 PF14570.6 OQR81416.1 - 4.1 7.3 7.2 11 5.9 7.2 1.7 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain AA_permease_2 PF13520.6 OQR81417.1 - 0.03 13.2 6.2 0.047 12.5 6.2 1.3 1 1 0 1 1 1 0 Amino acid permease K-box PF01486.17 OQR81418.1 - 2.7e-07 30.7 2.4 4.1e-07 30.1 2.4 1.3 1 0 0 1 1 1 1 K-box region Lebercilin PF15619.6 OQR81418.1 - 0.014 15.1 1.9 0.02 14.5 1.9 1.2 1 0 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease BST2 PF16716.5 OQR81418.1 - 0.094 13.3 0.2 0.35 11.5 0.0 1.9 2 0 0 2 2 2 0 Bone marrow stromal antigen 2 LapA_dom PF06305.11 OQR81418.1 - 0.52 10.2 0.0 0.52 10.2 0.0 2.3 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain DUF1192 PF06698.11 OQR81418.1 - 7.1 6.8 6.2 8.1 6.6 1.3 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1192) CNOT11 PF10155.9 OQR81419.1 - 5.6e-54 181.6 7.5 5.6e-54 181.6 7.5 2.5 3 0 0 3 3 3 1 CCR4-NOT transcription complex subunit 11 CRAL_TRIO PF00650.20 OQR81419.1 - 1.7e-27 96.1 1.8 2.2e-27 95.7 0.4 2.0 2 0 0 2 2 2 1 CRAL/TRIO domain Tub PF01167.18 OQR81419.1 - 1.1e-23 84.3 0.0 2.4e-23 83.2 0.0 1.6 1 0 0 1 1 1 1 Tub family FYVE PF01363.21 OQR81419.1 - 7.5e-13 48.4 5.9 1.9e-12 47.1 5.9 1.7 1 0 0 1 1 1 1 FYVE zinc finger DUF4131 PF13567.6 OQR81419.1 - 0.15 11.7 2.4 0.25 11.0 2.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) Cript PF10235.9 OQR81419.1 - 2.9 8.5 6.6 1.5 9.4 3.4 2.2 2 0 0 2 2 2 0 Microtubule-associated protein CRIPT ALAD PF00490.21 OQR81420.1 - 7.8e-56 189.5 0.0 8.9e-56 189.4 0.0 1.0 1 0 0 1 1 1 1 Delta-aminolevulinic acid dehydratase ALAD PF00490.21 OQR81421.1 - 3.7e-39 134.8 0.1 4.1e-39 134.6 0.1 1.0 1 0 0 1 1 1 1 Delta-aminolevulinic acid dehydratase PAC3 PF10178.9 OQR81422.1 - 2.9e-11 43.4 0.0 3e-11 43.3 0.0 1.0 1 0 0 1 1 1 1 Proteasome assembly chaperone 3 Sacchrp_dh_NADP PF03435.18 OQR81423.1 - 2e-19 70.2 0.0 3.1e-19 69.5 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Sacchrp_dh_C PF16653.5 OQR81423.1 - 5.5e-06 26.7 0.0 2e-05 24.8 0.0 1.8 1 1 0 1 1 1 1 Saccharopine dehydrogenase C-terminal domain KR PF08659.10 OQR81423.1 - 0.0093 15.9 0.0 0.017 15.0 0.0 1.4 1 0 0 1 1 1 1 KR domain 3Beta_HSD PF01073.19 OQR81423.1 - 0.026 13.5 0.0 0.039 13.0 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family DUF2781 PF10914.8 OQR81424.1 - 3.3e-11 43.8 11.7 8.6e-11 42.4 6.2 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF2781) FixP_N PF14715.6 OQR81424.1 - 0.88 9.4 6.0 0.11 12.2 0.8 2.2 2 1 1 3 3 3 0 N-terminal domain of cytochrome oxidase-cbb3, FixP Mito_carr PF00153.27 OQR81425.1 - 1e-60 201.6 6.8 1.1e-24 86.2 0.0 4.0 2 1 1 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 OQR81425.1 - 0.0012 18.0 0.3 0.0076 15.4 0.0 2.4 3 0 0 3 3 3 1 Gammaproteobacterial serine protease zf-Tim10_DDP PF02953.15 OQR81426.1 - 4e-17 61.6 5.2 5.8e-17 61.1 5.2 1.2 1 0 0 1 1 1 1 Tim10/DDP family zinc finger Hormone_recep PF00104.30 OQR81426.1 - 0.023 14.3 1.6 0.026 14.1 1.6 1.2 1 0 0 1 1 1 0 Ligand-binding domain of nuclear hormone receptor DUF2116 PF09889.9 OQR81426.1 - 2.4 8.2 5.5 0.62 10.1 0.8 2.1 1 1 1 2 2 2 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) Na_H_antiporter PF03553.14 OQR81427.1 - 3.4e-31 108.6 18.9 5e-31 108.1 8.2 3.1 2 1 0 2 2 2 2 Na+/H+ antiporter family DUF3417 PF11897.8 OQR81428.1 - 1.4 9.4 6.1 0.3 11.6 0.3 3.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3417) SKN1 PF03935.15 OQR81430.1 - 9.3e-60 202.4 22.9 3.2e-25 88.5 3.4 5.1 4 2 0 4 4 4 4 Beta-glucan synthesis-associated protein (SKN1) EB PF01683.18 OQR81430.1 - 0.014 15.7 2.0 0.014 15.7 2.0 2.1 2 0 0 2 2 2 0 EB module JmjC PF02373.22 OQR81432.1 - 5e-37 126.8 1.6 2.6e-36 124.5 0.1 2.4 2 0 0 2 2 2 1 JmjC domain, hydroxylase PHD PF00628.29 OQR81432.1 - 0.026 14.4 6.5 0.059 13.3 6.5 1.6 1 0 0 1 1 1 0 PHD-finger DUF5543 PF17697.1 OQR81432.1 - 0.32 11.3 1.6 0.74 10.1 1.6 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5543) PHD_2 PF13831.6 OQR81432.1 - 3.1 7.4 10.0 31 4.2 10.1 2.4 1 1 0 1 1 1 0 PHD-finger PB1 PF00564.24 OQR81433.1 - 9.5e-08 31.9 0.3 1.4e-07 31.4 0.3 1.3 1 0 0 1 1 1 1 PB1 domain UPF0767 PF15990.5 OQR81433.1 - 0.11 12.7 0.3 0.21 11.7 0.3 1.5 1 0 0 1 1 1 0 UPF0767 family Ank_2 PF12796.7 OQR81434.1 - 4.3e-20 72.1 4.6 2.7e-05 24.7 0.2 4.4 2 2 1 4 4 4 4 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OQR81434.1 - 2.6e-18 65.8 2.9 3.5e-08 33.6 0.2 4.9 4 1 1 5 5 5 4 Ankyrin repeats (many copies) Ank_4 PF13637.6 OQR81434.1 - 4e-16 59.1 1.8 9.4e-09 35.6 0.0 4.6 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQR81434.1 - 5.9e-15 53.9 1.9 0.015 15.8 0.0 5.7 5 0 0 5 5 5 4 Ankyrin repeat Ank PF00023.30 OQR81434.1 - 1.3e-11 44.4 5.6 0.0027 18.1 0.3 5.1 4 1 0 4 4 4 3 Ankyrin repeat DUF2321 PF10083.9 OQR81434.1 - 0.19 11.4 1.5 0.54 9.9 1.5 1.8 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2321) Phage-MuB_C PF09077.11 OQR81434.1 - 1.1 9.2 3.5 14 5.7 0.1 3.2 3 0 0 3 3 3 0 Mu B transposition protein, C terminal Pkip-1 PF06878.11 OQR81434.1 - 3.7 7.6 6.9 0.59 10.2 2.0 2.2 2 0 0 2 2 2 0 Pkip-1 protein PSP1 PF04468.12 OQR81435.1 - 5.1e-30 103.6 4.9 8.3e-30 102.9 4.9 1.4 1 0 0 1 1 1 1 PSP1 C-terminal conserved region Pkinase_Tyr PF07714.17 OQR81436.1 - 1.5e-89 299.7 0.0 1.1e-43 149.4 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 OQR81436.1 - 2e-84 283.1 0.0 2.5e-42 145.1 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain DEP PF00610.21 OQR81436.1 - 5.5e-19 68.0 3.1 3.1e-09 36.7 0.1 3.0 3 0 0 3 3 3 2 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) APH PF01636.23 OQR81436.1 - 3.1e-05 24.0 0.9 0.19 11.6 0.2 3.0 2 1 0 2 2 2 2 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 OQR81436.1 - 0.001 17.9 0.0 0.44 9.3 0.0 2.2 2 0 0 2 2 2 2 Fungal protein kinase ABC1 PF03109.16 OQR81436.1 - 0.0026 17.9 0.6 1 9.5 0.1 2.7 2 0 0 2 2 2 2 ABC1 family Seadorna_VP7 PF07387.11 OQR81436.1 - 0.0096 15.0 0.0 4.5 6.2 0.0 2.4 2 0 0 2 2 2 2 Seadornavirus VP7 Vmethyltransf PF01660.17 OQR81436.1 - 0.012 14.5 0.1 0.41 9.5 0.0 2.3 2 0 0 2 2 2 0 Viral methyltransferase Kinase-like PF14531.6 OQR81436.1 - 0.018 14.4 0.0 8.2 5.6 0.0 2.8 3 0 0 3 3 3 0 Kinase-like Pox_ser-thr_kin PF05445.11 OQR81436.1 - 0.09 11.7 0.2 8 5.3 0.0 2.7 2 0 0 2 2 2 0 Poxvirus serine/threonine protein kinase Haspin_kinase PF12330.8 OQR81436.1 - 0.091 11.7 0.3 11 4.8 0.0 2.7 3 0 0 3 3 3 0 Haspin like kinase domain Kelch_5 PF13854.6 OQR81436.1 - 0.76 9.8 2.8 1.1 9.3 0.3 2.5 2 0 0 2 2 2 0 Kelch motif GWT1 PF06423.12 OQR81437.1 - 1.5e-26 93.3 4.7 1.5e-26 93.3 4.7 3.2 3 1 1 4 4 4 1 GWT1 IQ PF00612.27 OQR81439.1 - 5.5e-05 22.6 23.1 0.26 11.2 1.4 6.4 5 0 0 5 5 5 3 IQ calmodulin-binding motif DUF1272 PF06906.11 OQR81439.1 - 0.011 15.8 1.3 0.031 14.4 1.3 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) HypA PF01155.19 OQR81439.1 - 4 7.5 6.3 6.7 6.8 0.6 3.3 3 0 0 3 3 3 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA rve_3 PF13683.6 OQR81439.1 - 4.5 7.1 0.0 4.5 7.1 0.0 4.3 5 0 0 5 5 5 0 Integrase core domain DUF5047 PF16466.5 OQR81440.1 - 0.17 12.2 0.0 0.45 10.9 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF5047) cEGF PF12662.7 OQR81441.1 - 2.5 8.1 8.3 13 5.8 8.3 2.4 1 0 0 1 1 1 0 Complement Clr-like EGF-like Acetyltransf_10 PF13673.7 OQR81443.1 - 3e-13 49.8 0.1 3.4e-13 49.7 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 OQR81443.1 - 1.4e-12 47.9 0.0 1.7e-12 47.6 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 OQR81443.1 - 8.6e-11 42.1 0.0 1.3e-10 41.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 OQR81443.1 - 9.7e-05 22.3 0.2 0.0002 21.3 0.2 1.5 2 0 0 2 2 2 1 FR47-like protein PanZ PF12568.8 OQR81443.1 - 0.00015 21.5 0.0 0.00018 21.3 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain, PanZ Acetyltransf_4 PF13420.7 OQR81443.1 - 0.0024 18.0 0.1 0.0039 17.3 0.1 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 OQR81443.1 - 0.0048 17.0 0.0 0.02 14.9 0.0 1.9 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_15 PF17013.5 OQR81443.1 - 0.013 15.0 0.1 0.016 14.7 0.1 1.1 1 0 0 1 1 1 0 Putative acetyl-transferase Acetyltransf_CG PF14542.6 OQR81443.1 - 0.031 14.4 0.0 0.066 13.4 0.0 1.5 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase HHH_4 PF14490.6 OQR81443.1 - 0.04 13.9 0.0 1.5 8.9 0.0 2.2 2 0 0 2 2 2 0 Helix-hairpin-helix containing domain ADP_ribosyl_GH PF03747.14 OQR81446.1 - 1.4e-25 90.7 0.0 2.4e-25 89.9 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylglycohydrolase PEPCK_ATP PF01293.20 OQR81446.1 - 0.0041 15.8 0.0 0.0065 15.2 0.0 1.2 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase Ank_2 PF12796.7 OQR81447.1 - 4.9e-10 39.9 3.0 5.6e-05 23.6 0.1 2.5 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQR81447.1 - 1.4e-08 35.1 0.7 0.00031 21.2 0.1 3.2 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 OQR81447.1 - 1e-07 32.1 3.1 0.2 12.0 0.0 4.1 2 2 2 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQR81447.1 - 2.1e-07 30.7 0.4 2.7 8.8 0.0 4.2 4 0 0 4 4 4 3 Ankyrin repeat Ank PF00023.30 OQR81447.1 - 0.00082 19.7 0.4 4.4 7.9 0.0 3.8 2 1 0 2 2 2 1 Ankyrin repeat DUF3447 PF11929.8 OQR81447.1 - 0.17 11.9 1.6 0.95 9.5 0.1 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3447) ABC2_membrane_3 PF12698.7 OQR81448.1 - 1.9e-17 63.4 9.8 9.1e-17 61.2 9.8 1.9 1 1 0 1 1 1 1 ABC-2 family transporter protein AAA_21 PF13304.6 OQR81448.1 - 0.16 11.7 0.0 0.27 11.0 0.0 1.2 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system FA_desaturase PF00487.24 OQR81449.1 - 0.023 14.6 0.1 0.027 14.3 0.1 1.1 1 0 0 1 1 1 0 Fatty acid desaturase Ank_2 PF12796.7 OQR81451.1 - 4.7e-14 52.7 11.8 2.4e-05 24.8 0.1 3.2 2 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OQR81451.1 - 6.2e-07 29.2 1.6 44 5.1 0.0 6.0 6 0 0 6 6 6 1 Ankyrin repeat Ank_5 PF13857.6 OQR81451.1 - 3.3e-06 27.3 3.5 0.19 12.1 0.0 4.5 2 2 3 5 5 5 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 OQR81451.1 - 5.9e-05 23.5 9.0 0.022 15.4 0.0 4.9 5 1 1 6 6 6 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 OQR81452.1 - 1.1e-14 54.8 5.9 1.6e-05 25.4 0.1 3.6 2 1 2 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQR81452.1 - 1.4e-11 44.6 8.5 3e-05 24.5 0.0 5.6 4 1 2 6 6 6 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQR81452.1 - 6.7e-07 29.1 9.4 17 6.4 0.1 7.9 7 1 1 8 8 8 1 Ankyrin repeat Ank_5 PF13857.6 OQR81452.1 - 1.2e-06 28.7 7.3 0.84 10.0 0.0 5.8 3 1 3 6 6 6 4 Ankyrin repeats (many copies) Ank PF00023.30 OQR81452.1 - 0.013 15.9 5.4 64 4.3 0.0 5.8 1 1 1 3 3 3 0 Ankyrin repeat Ion_trans PF00520.31 OQR81453.1 - 2.1e-20 73.0 12.8 3.1e-20 72.4 12.8 1.2 1 0 0 1 1 1 1 Ion transport protein cNMP_binding PF00027.29 OQR81453.1 - 1.4e-12 47.5 0.0 2.6e-12 46.6 0.0 1.5 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Ion_trans_2 PF07885.16 OQR81453.1 - 4.7e-11 42.5 4.7 1.5e-10 40.9 4.7 1.9 1 0 0 1 1 1 1 Ion channel DUF2189 PF09955.9 OQR81453.1 - 0.1 12.9 4.0 0.71 10.1 4.0 2.3 1 1 0 1 1 1 0 Predicted integral membrane protein (DUF2189) Trypsin_2 PF13365.6 OQR81454.1 - 0.00014 22.8 0.0 0.00032 21.6 0.0 1.6 1 1 0 1 1 1 1 Trypsin-like peptidase domain Ion_trans PF00520.31 OQR81455.1 - 1.6e-26 93.1 8.3 2.2e-26 92.6 8.3 1.1 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 OQR81455.1 - 1e-14 54.2 3.5 1e-14 54.2 3.5 2.3 2 1 0 2 2 2 1 Ion channel PKD_channel PF08016.12 OQR81455.1 - 0.0008 18.2 6.1 0.0016 17.2 1.2 2.0 1 1 1 2 2 2 2 Polycystin cation channel NrsF PF06532.11 OQR81455.1 - 0.0041 16.9 2.1 0.0041 16.9 2.1 2.5 1 1 1 3 3 3 1 Negative regulator of sigma F zinc_ribbon_2 PF13240.6 OQR81455.1 - 0.019 14.7 0.1 0.035 13.8 0.1 1.4 1 0 0 1 1 1 0 zinc-ribbon domain IBR PF01485.21 OQR81455.1 - 0.048 13.9 0.5 0.083 13.1 0.5 1.3 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain MFS_MOT1 PF16983.5 OQR81455.1 - 0.062 13.7 4.2 4.8 7.6 0.4 2.4 2 0 0 2 2 2 0 Molybdate transporter of MFS superfamily HEAT PF02985.22 OQR81456.1 - 0.076 13.3 0.4 4.4 7.8 0.0 2.9 2 1 1 3 3 3 0 HEAT repeat DUF5350 PF17299.2 OQR81456.1 - 1.3 9.6 4.5 0.27 11.8 0.4 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF5350) FYVE PF01363.21 OQR81457.1 - 1.4e-10 41.2 12.8 1.4e-10 41.2 12.8 2.2 2 0 0 2 2 2 1 FYVE zinc finger NOB1_Zn_bind PF08772.11 OQR81457.1 - 0.021 15.0 5.6 0.021 15.0 5.6 2.1 2 0 0 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like 2OG-FeII_Oxy_3 PF13640.6 OQR81458.1 - 3.7e-16 59.8 0.0 7.2e-16 58.9 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily zf-MYND PF01753.18 OQR81458.1 - 9.4e-10 38.4 16.3 2e-09 37.3 16.3 1.6 1 0 0 1 1 1 1 MYND finger 2OG-FeII_Oxy_4 PF13661.6 OQR81458.1 - 3.1e-08 34.2 0.0 8.6e-08 32.7 0.0 1.7 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily PhyH PF05721.13 OQR81458.1 - 0.0087 16.3 0.0 0.014 15.7 0.0 1.3 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Cyclin_N PF00134.23 OQR81459.1 - 2.2e-09 37.1 0.5 1.1e-07 31.7 0.1 2.4 2 0 0 2 2 2 1 Cyclin, N-terminal domain zf-C2H2_4 PF13894.6 OQR81459.1 - 3e-09 36.9 20.2 0.0012 19.6 0.7 4.1 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2 PF00096.26 OQR81459.1 - 1.6e-08 34.5 28.6 0.00044 20.6 0.4 4.1 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 OQR81459.1 - 1.1e-07 31.9 21.7 5.1e-07 29.8 0.8 4.1 4 0 0 4 4 4 2 Zinc-finger double domain TBX PF12598.8 OQR81459.1 - 0.01 16.6 8.1 0.043 14.6 2.0 2.7 2 0 0 2 2 2 0 T-box transcription factor DUF5557 PF17712.1 OQR81459.1 - 0.05 13.5 0.0 0.14 12.1 0.0 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5557) zf-met PF12874.7 OQR81459.1 - 0.072 13.5 4.9 0.13 12.7 1.0 3.2 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 OQR81459.1 - 2.1 8.7 6.9 0.84 10.0 0.6 3.1 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding 2-Hacid_dh_C PF02826.19 OQR81460.1 - 3.4e-58 195.9 0.0 5.2e-58 195.3 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 OQR81460.1 - 5e-27 94.2 0.0 6e-27 93.9 0.0 1.0 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 OQR81460.1 - 0.017 15.3 0.0 0.06 13.5 0.0 1.8 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase VOMI PF03762.17 OQR81460.1 - 0.034 14.3 0.0 0.056 13.6 0.0 1.2 1 0 0 1 1 1 0 Vitelline membrane outer layer protein I (VOMI) IlvN PF07991.12 OQR81460.1 - 0.1 12.1 0.0 0.25 10.9 0.0 1.6 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain GFO_IDH_MocA PF01408.22 OQR81460.1 - 0.11 13.4 0.0 0.25 12.2 0.0 1.6 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold KRAB PF01352.27 OQR81461.1 - 0.2 11.3 1.8 3.3 7.4 0.1 2.5 2 0 0 2 2 2 0 KRAB box Csm1_N PF18504.1 OQR81461.1 - 1.7 9.1 7.5 0.85 10.0 1.1 3.1 2 0 0 2 2 2 0 Csm1 N-terminal domain Lzipper-MIP1 PF14389.6 OQR81461.1 - 2.8 8.3 8.8 0.48 10.7 0.3 2.9 4 0 0 4 4 4 0 Leucine-zipper of ternary complex factor MIP1 CNDH2_C PF16858.5 OQR81462.1 - 6.4e-49 167.4 0.1 6.4e-49 167.4 0.1 2.3 3 0 0 3 3 3 1 Condensin II complex subunit CAP-H2 or CNDH2, C-term CNDH2_N PF06278.11 OQR81462.1 - 3.7e-21 75.5 1.7 1.2e-20 73.8 0.4 2.2 2 0 0 2 2 2 1 Condensin II complex subunit CAP-H2 or CNDH2, N-terminal Spc7 PF08317.11 OQR81463.1 - 0.035 13.0 38.9 0.13 11.1 5.8 2.6 2 1 1 3 3 3 0 Spc7 kinetochore protein DUF3138 PF11336.8 OQR81463.1 - 0.38 9.3 10.1 0.23 10.0 6.1 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF3138) DUF4407 PF14362.6 OQR81463.1 - 9.4 5.5 27.6 1.2 8.4 19.2 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4407) zf-CCCH PF00642.24 OQR81464.1 - 0.0029 17.5 3.7 0.0056 16.6 3.7 1.5 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) tRNA_anti-codon PF01336.25 OQR81464.1 - 0.021 14.8 0.0 0.045 13.7 0.0 1.5 1 0 0 1 1 1 0 OB-fold nucleic acid binding domain Ubie_methyltran PF01209.18 OQR81464.1 - 0.13 11.6 0.0 0.25 10.6 0.0 1.4 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family HLH PF00010.26 OQR81465.1 - 7.5e-10 38.6 0.4 1.6e-09 37.5 0.4 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Abhydrolase_1 PF00561.20 OQR81466.1 - 6.8e-34 117.7 0.0 1e-33 117.1 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 OQR81466.1 - 2.2e-12 46.7 0.0 4.4e-11 42.5 0.0 2.2 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 OQR81466.1 - 8.4e-08 33.1 0.1 1.2e-07 32.5 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_4 PF08386.10 OQR81466.1 - 0.00011 22.3 0.0 0.00021 21.4 0.0 1.4 1 0 0 1 1 1 1 TAP-like protein Peptidase_S28 PF05577.12 OQR81466.1 - 0.02 13.7 0.0 0.057 12.2 0.0 1.7 2 0 0 2 2 2 0 Serine carboxypeptidase S28 Bot1p PF12298.8 OQR81467.1 - 0.014 15.5 0.6 0.043 14.0 0.6 1.9 1 1 0 1 1 1 0 Eukaryotic mitochondrial regulator protein MRP-L20 PF12824.7 OQR81467.1 - 0.023 14.9 0.9 0.16 12.1 0.0 2.3 2 1 0 2 2 2 0 Mitochondrial ribosomal protein subunit L20 Aminotran_3 PF00202.21 OQR81468.1 - 3e-116 388.4 0.0 3.8e-116 388.1 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 OQR81468.1 - 8.5e-05 21.9 0.0 0.00015 21.1 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 OQR81468.1 - 0.0022 17.0 0.1 0.017 14.1 0.1 2.0 1 1 0 1 1 1 1 Aminotransferase class-V LisH PF08513.11 OQR81469.1 - 0.036 14.0 0.2 0.1 12.6 0.2 1.9 1 0 0 1 1 1 0 LisH ANAPC4_WD40 PF12894.7 OQR81469.1 - 0.036 14.4 0.4 45 4.4 0.0 4.2 1 1 1 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain Topoisom_bac PF01131.20 OQR81470.1 - 2.8e-103 346.1 0.0 4.1e-103 345.6 0.0 1.3 1 0 0 1 1 1 1 DNA topoisomerase zf-GRF PF06839.12 OQR81470.1 - 6e-31 106.3 12.4 7.9e-17 61.1 4.5 3.0 2 0 0 2 2 2 2 GRF zinc finger Toprim PF01751.22 OQR81470.1 - 6.1e-18 64.9 0.0 1.5e-17 63.7 0.0 1.7 1 0 0 1 1 1 1 Toprim domain zf-C4_Topoisom PF01396.19 OQR81470.1 - 0.0015 18.3 1.4 0.0015 18.3 1.4 4.4 5 0 0 5 5 5 1 Topoisomerase DNA binding C4 zinc finger Sfi1_C PF10638.9 OQR81470.1 - 0.45 11.3 2.9 1.1 10.1 0.9 2.5 3 0 0 3 3 3 0 Spindle body associated protein C-terminus SapB_1 PF05184.15 OQR81470.1 - 5.7 7.0 8.6 11 6.1 0.3 3.9 3 0 0 3 3 3 0 Saposin-like type B, region 1 OrfB_Zn_ribbon PF07282.11 OQR81470.1 - 9.8 6.2 8.0 1.1 9.2 0.1 3.3 2 1 1 3 3 3 0 Putative transposase DNA-binding domain EamA PF00892.20 OQR81471.1 - 0.0036 17.5 8.2 0.0036 17.5 8.2 3.6 2 2 0 2 2 2 1 EamA-like transporter family tRNA-synt_2 PF00152.20 OQR81472.1 - 5e-87 291.9 0.0 6.2e-87 291.6 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 OQR81472.1 - 3.1e-12 46.3 0.1 5.1e-12 45.6 0.1 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA_anti_2 PF13742.6 OQR81472.1 - 1.8e-05 24.9 0.0 5e-05 23.4 0.0 1.8 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 OQR81472.1 - 0.00099 18.7 0.1 0.017 14.6 0.0 2.3 2 0 0 2 2 2 1 tRNA synthetases class II core domain (F) DUF4253 PF14062.6 OQR81473.1 - 0.00026 21.1 3.2 0.52 10.5 0.4 3.3 2 1 1 3 3 3 2 Domain of unknown function (DUF4253) Lectin_like PF18560.1 OQR81473.1 - 0.02 15.0 0.5 0.066 13.4 0.3 2.0 1 1 1 2 2 2 0 Lectin like domain COMP PF11598.8 OQR81473.1 - 0.041 14.4 8.3 8.3 7.0 0.3 5.3 6 0 0 6 6 6 0 Cartilage oligomeric matrix protein P-mevalo_kinase PF04275.14 OQR81473.1 - 0.074 13.0 1.0 0.18 11.7 0.7 1.8 1 1 0 1 1 1 0 Phosphomevalonate kinase KASH_CCD PF14662.6 OQR81473.1 - 9.2 6.0 40.1 6.5 6.5 18.9 2.8 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 or KASH HrpB7 PF09486.10 OQR81473.1 - 9.4 6.6 10.2 0.43 10.9 1.1 2.9 2 1 0 2 2 2 0 Bacterial type III secretion protein (HrpB7) HSP70 PF00012.20 OQR81475.1 - 2.6e-265 881.3 5.9 2.9e-265 881.1 5.9 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 OQR81475.1 - 3.6e-15 55.6 0.1 3.9e-14 52.2 0.0 2.0 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.16 OQR81475.1 - 0.0016 18.2 0.0 0.0053 16.5 0.0 1.8 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain DDR PF08841.10 OQR81475.1 - 0.017 14.2 0.4 0.098 11.6 0.2 2.1 2 0 0 2 2 2 0 Diol dehydratase reactivase ATPase-like domain Hydantoinase_A PF01968.18 OQR81475.1 - 0.026 13.8 1.0 0.32 10.2 0.1 2.5 1 1 1 2 2 2 0 Hydantoinase/oxoprolinase PixA PF12306.8 OQR81475.1 - 0.052 13.7 0.5 0.12 12.5 0.5 1.7 1 0 0 1 1 1 0 Inclusion body protein MutS_III PF05192.18 OQR81475.1 - 0.21 11.8 2.0 13 6.0 1.3 2.4 2 0 0 2 2 2 0 MutS domain III PTPS PF01242.19 OQR81476.1 - 6.3e-22 77.8 0.2 7.5e-22 77.6 0.2 1.1 1 0 0 1 1 1 1 6-pyruvoyl tetrahydropterin synthase MatE PF01554.18 OQR81477.1 - 9.7e-48 161.9 33.6 2.5e-25 89.0 11.7 2.2 2 0 0 2 2 2 2 MatE Polysacc_synt_C PF14667.6 OQR81477.1 - 0.0029 17.7 24.8 0.0096 16.0 3.7 4.4 2 2 2 4 4 4 2 Polysaccharide biosynthesis C-terminal domain Pkinase_Tyr PF07714.17 OQR81478.1 - 9.8e-54 182.3 0.0 1.3e-53 182.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OQR81478.1 - 1e-49 169.3 0.0 1.4e-49 168.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Haspin_kinase PF12330.8 OQR81478.1 - 0.0018 17.3 0.0 0.008 15.2 0.0 1.9 1 1 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 OQR81478.1 - 0.0049 15.7 0.0 0.0075 15.1 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 OQR81478.1 - 0.043 13.7 0.0 0.066 13.1 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family AMA-1 PF02430.15 OQR81478.1 - 0.12 11.3 0.6 0.19 10.7 0.6 1.2 1 0 0 1 1 1 0 Apical membrane antigen 1 DUF515 PF04415.12 OQR81478.1 - 0.16 10.3 0.7 0.23 9.8 0.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF515) DUF4537 PF15057.6 OQR81479.1 - 0.0017 18.4 0.0 1.2 9.1 0.0 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF4537) Toxin_34 PF08396.10 OQR81479.1 - 0.0022 18.7 1.8 2.1 9.2 0.1 3.0 2 0 0 2 2 2 2 Spider toxin omega agatoxin/Tx1 family HSP70 PF00012.20 OQR81480.1 - 2.1e-169 564.6 5.4 2.8e-169 564.1 5.4 1.1 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 OQR81480.1 - 2.8e-15 56.0 0.1 3.3e-14 52.4 0.0 2.1 2 0 0 2 2 2 1 MreB/Mbl protein FtsA PF14450.6 OQR81480.1 - 0.00029 21.2 0.2 0.044 14.2 0.1 3.1 2 1 0 2 2 2 1 Cell division protein FtsA FGGY_C PF02782.16 OQR81480.1 - 0.00076 19.2 0.0 0.0015 18.3 0.0 1.5 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain DUF11 PF01345.18 OQR81480.1 - 0.0032 17.7 0.2 0.0091 16.3 0.2 1.7 1 0 0 1 1 1 1 Domain of unknown function DUF11 Hydantoinase_A PF01968.18 OQR81480.1 - 0.035 13.4 0.1 0.069 12.4 0.1 1.4 1 0 0 1 1 1 0 Hydantoinase/oxoprolinase DDR PF08841.10 OQR81480.1 - 0.036 13.1 0.2 0.26 10.3 0.1 2.2 2 0 0 2 2 2 0 Diol dehydratase reactivase ATPase-like domain Ppx-GppA PF02541.16 OQR81480.1 - 0.038 13.4 0.0 0.08 12.4 0.0 1.5 1 0 0 1 1 1 0 Ppx/GppA phosphatase family HSF_DNA-bind PF00447.17 OQR81481.1 - 2.2e-25 89.1 1.1 3.5e-25 88.5 1.1 1.3 1 0 0 1 1 1 1 HSF-type DNA-binding TolA_bind_tri PF16331.5 OQR81481.1 - 0.0053 16.8 5.9 0.0096 16.0 5.9 1.4 1 0 0 1 1 1 1 TolA binding protein trimerisation YabA PF06156.13 OQR81481.1 - 0.8 10.4 3.4 1.7 9.3 3.4 1.5 1 0 0 1 1 1 0 Initiation control protein YabA FYVE PF01363.21 OQR81482.1 - 5.9e-07 29.5 16.1 9.4e-07 28.9 16.1 1.3 1 0 0 1 1 1 1 FYVE zinc finger DUF3678 PF12435.8 OQR81482.1 - 0.02 14.2 0.8 0.02 14.2 0.8 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3678) FYVE_2 PF02318.16 OQR81482.1 - 0.74 10.0 12.3 1.3 9.2 12.3 1.4 1 0 0 1 1 1 0 FYVE-type zinc finger DZR PF12773.7 OQR81482.1 - 4.9 7.3 15.4 27 4.9 7.9 2.5 1 1 1 2 2 2 0 Double zinc ribbon C1_2 PF03107.16 OQR81482.1 - 7.2 7.0 15.4 3.3 8.1 7.9 2.7 3 0 0 3 3 3 0 C1 domain HAT_KAT11 PF08214.11 OQR81484.1 - 1.6e-29 103.3 2.1 9.9e-28 97.4 0.4 2.7 2 1 0 2 2 2 1 Histone acetylation protein Bromodomain PF00439.25 OQR81484.1 - 4.8e-16 58.6 0.0 1.1e-15 57.4 0.0 1.7 1 0 0 1 1 1 1 Bromodomain zf-TAZ PF02135.16 OQR81484.1 - 4.7e-10 39.8 13.1 4.7e-10 39.8 13.1 3.9 2 2 1 3 3 3 2 TAZ zinc finger ZZ PF00569.17 OQR81484.1 - 7e-08 32.2 4.6 7e-08 32.2 4.6 4.8 5 0 0 5 5 5 1 Zinc finger, ZZ type PHD PF00628.29 OQR81484.1 - 3.2e-06 26.9 3.6 3.2e-06 26.9 3.6 5.9 7 2 1 8 8 8 1 PHD-finger DUF902 PF06001.13 OQR81484.1 - 0.0065 16.9 3.6 0.0065 16.9 3.6 2.1 2 0 0 2 2 2 1 Domain of Unknown Function (DUF902) zf-H2C2_2 PF13465.6 OQR81484.1 - 3.2 8.3 7.5 0.89 10.1 0.3 4.0 2 1 1 3 3 3 0 Zinc-finger double domain DUF3293 PF11697.8 OQR81485.1 - 6.1e-13 49.0 0.0 9.2e-13 48.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3293) NOT2_3_5 PF04153.18 OQR81486.1 - 7.3e-13 48.7 1.6 2.1e-12 47.3 1.6 1.8 1 0 0 1 1 1 1 NOT2 / NOT3 / NOT5 family SPESP1 PF15754.5 OQR81486.1 - 0.012 14.8 0.9 0.016 14.4 0.9 1.1 1 0 0 1 1 1 0 Sperm equatorial segment protein 1 tRNA_NucTransf2 PF09249.11 OQR81486.1 - 0.14 12.4 0.0 0.31 11.3 0.0 1.5 1 0 0 1 1 1 0 tRNA nucleotidyltransferase, second domain Hid1 PF12722.7 OQR81486.1 - 7.3 4.6 7.1 9.9 4.1 7.1 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Pkinase PF00069.25 OQR81487.1 - 5e-48 163.8 0.0 6.7e-48 163.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQR81487.1 - 5.2e-45 153.7 0.0 6.5e-45 153.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Ank_4 PF13637.6 OQR81487.1 - 8.4e-08 32.6 0.0 0.00076 20.0 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 OQR81487.1 - 3.3e-07 30.8 0.0 7.2e-07 29.7 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OQR81487.1 - 2.8e-05 24.3 0.2 0.00014 22.1 0.1 2.1 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQR81487.1 - 0.0003 21.0 0.0 0.0092 16.4 0.0 3.0 3 0 0 3 3 3 1 Ankyrin repeat Ank PF00023.30 OQR81487.1 - 0.00051 20.4 0.0 0.13 12.8 0.0 2.9 2 0 0 2 2 2 1 Ankyrin repeat Pkinase_fungal PF17667.1 OQR81487.1 - 0.023 13.5 0.0 0.074 11.8 0.0 1.7 2 0 0 2 2 2 0 Fungal protein kinase Haspin_kinase PF12330.8 OQR81487.1 - 0.047 12.6 0.1 0.82 8.5 0.1 2.1 1 1 0 1 1 1 0 Haspin like kinase domain ABC1 PF03109.16 OQR81487.1 - 0.05 13.8 0.0 0.19 11.9 0.0 1.9 2 0 0 2 2 2 0 ABC1 family CHCH PF06747.13 OQR81488.1 - 3.7e-06 26.9 7.7 5.6e-06 26.3 7.7 1.3 1 0 0 1 1 1 1 CHCH domain COX6B PF02297.17 OQR81488.1 - 0.045 14.0 3.3 0.068 13.4 3.3 1.2 1 0 0 1 1 1 0 Cytochrome oxidase c subunit VIb Pet191_N PF10203.9 OQR81488.1 - 0.13 12.6 2.9 0.19 12.1 2.9 1.2 1 0 0 1 1 1 0 Cytochrome c oxidase assembly protein PET191 CX9C PF16860.5 OQR81488.1 - 0.33 11.0 4.8 0.57 10.2 4.8 1.4 1 0 0 1 1 1 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, Cupin_4 PF08007.12 OQR81489.1 - 2.9e-69 234.0 0.0 3.9e-69 233.6 0.0 1.1 1 0 0 1 1 1 1 Cupin superfamily protein Cupin_8 PF13621.6 OQR81489.1 - 4.7e-06 26.5 0.0 0.00059 19.6 0.0 2.4 1 1 0 1 1 1 1 Cupin-like domain Cupin_1 PF00190.22 OQR81489.1 - 0.0059 16.2 0.0 0.0098 15.5 0.0 1.3 1 0 0 1 1 1 1 Cupin Cupin_2 PF07883.11 OQR81489.1 - 0.077 12.7 0.0 0.32 10.7 0.0 1.9 2 0 0 2 2 2 0 Cupin domain MutS_V PF00488.21 OQR81490.1 - 2e-74 249.7 0.0 5e-74 248.4 0.0 1.7 2 0 0 2 2 2 1 MutS domain V MutS_III PF05192.18 OQR81490.1 - 1.2e-33 116.9 0.6 2.2e-33 116.1 0.6 1.4 1 0 0 1 1 1 1 MutS domain III MutS_IV PF05190.18 OQR81490.1 - 3e-14 53.1 0.1 6.6e-14 52.0 0.1 1.6 1 0 0 1 1 1 1 MutS family domain IV AAA_29 PF13555.6 OQR81490.1 - 0.16 11.7 0.0 0.44 10.3 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain Ank_2 PF12796.7 OQR81492.1 - 2e-81 268.7 27.6 1.7e-19 70.1 0.1 8.4 5 1 5 10 10 10 9 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQR81492.1 - 9.6e-63 207.8 14.4 6.2e-11 42.6 0.1 11.0 6 3 5 11 11 11 10 Ankyrin repeats (many copies) Pkinase PF00069.25 OQR81492.1 - 4.7e-56 190.1 0.0 3.2e-44 151.3 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OQR81492.1 - 1.7e-53 181.6 0.0 3.3e-39 134.8 0.0 2.4 2 0 0 2 2 2 2 Protein tyrosine kinase Ank_5 PF13857.6 OQR81492.1 - 1e-52 175.5 19.1 1.5e-10 41.1 0.2 10.7 5 2 6 11 11 11 10 Ankyrin repeats (many copies) Ank PF00023.30 OQR81492.1 - 1e-51 171.2 30.6 6.8e-08 32.6 0.0 13.5 13 0 0 13 13 13 11 Ankyrin repeat Ank_3 PF13606.6 OQR81492.1 - 6e-43 139.9 13.8 0.0041 17.5 0.0 13.9 15 0 0 15 15 15 10 Ankyrin repeat ABC1 PF03109.16 OQR81492.1 - 3.3e-05 24.0 0.1 0.18 12.0 0.0 2.5 2 0 0 2 2 2 2 ABC1 family GrlR PF16518.5 OQR81492.1 - 0.0033 17.4 1.1 2.6 8.0 0.1 2.5 2 0 0 2 2 2 2 T3SS negative regulator,GrlR Pkinase_fungal PF17667.1 OQR81492.1 - 0.0086 14.9 0.0 0.018 13.8 0.0 1.5 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 OQR81492.1 - 0.063 12.2 0.0 0.11 11.4 0.0 1.4 1 0 0 1 1 1 0 Haspin like kinase domain Shigella_OspC PF06128.11 OQR81492.1 - 0.11 12.2 0.9 24 4.6 0.0 3.6 4 0 0 4 4 4 0 Shigella flexneri OspC protein PSS PF03034.15 OQR81493.1 - 4e-76 256.4 11.0 5.9e-76 255.8 11.0 1.3 1 0 0 1 1 1 1 Phosphatidyl serine synthase Bromodomain PF00439.25 OQR81493.1 - 1.3e-13 50.8 1.4 1.2e-12 47.7 0.1 2.9 3 1 0 3 3 3 1 Bromodomain ASXH PF13919.6 OQR81493.1 - 0.022 14.8 0.2 0.037 14.0 0.2 1.3 1 0 0 1 1 1 0 Asx homology domain FTHFS PF01268.19 OQR81494.1 - 2.1e-182 607.2 0.3 6.8e-137 457.0 0.5 2.0 1 1 1 2 2 2 2 Formate--tetrahydrofolate ligase DUF4106 PF13388.6 OQR81494.1 - 0.011 15.0 0.1 0.016 14.4 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) FAD_binding_1 PF00667.20 OQR81495.1 - 4.7e-49 166.9 0.0 2.2e-48 164.7 0.0 1.9 1 1 1 2 2 2 1 FAD binding domain Flavodoxin_1 PF00258.25 OQR81495.1 - 7e-21 74.9 0.0 1.2e-20 74.1 0.0 1.4 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.21 OQR81495.1 - 2.6e-16 60.2 0.0 4.3e-16 59.5 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Coatomer_WDAD PF04053.14 OQR81496.1 - 5.2e-07 29.1 0.0 0.00069 18.8 0.0 3.5 3 0 0 3 3 3 2 Coatomer WD associated region DUF3446 PF11928.8 OQR81496.1 - 0.046 14.0 0.6 0.2 12.0 0.6 2.1 1 0 0 1 1 1 0 Early growth response N-terminal domain SIS_2 PF13580.6 OQR81496.1 - 0.065 13.3 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 SIS domain Tax PF02959.16 OQR81496.1 - 0.074 12.5 0.2 0.23 10.9 0.0 1.8 2 0 0 2 2 2 0 HTLV Tax ANAPC4_WD40 PF12894.7 OQR81496.1 - 0.12 12.6 0.1 1.8 8.9 0.0 2.9 4 0 0 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 OQR81496.1 - 0.15 13.0 0.0 9.1 7.3 0.0 3.1 2 0 0 2 2 2 0 WD domain, G-beta repeat Sedlin_N PF04628.13 OQR81497.1 - 1.4e-28 99.6 0.5 1.8e-28 99.3 0.5 1.1 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Sybindin PF04099.12 OQR81497.1 - 3.6e-06 27.0 0.2 4.7e-06 26.6 0.2 1.2 1 0 0 1 1 1 1 Sybindin-like family WD40 PF00400.32 OQR81498.1 - 0.0023 18.7 1.0 8.8 7.4 0.0 3.7 4 0 0 4 4 4 2 WD domain, G-beta repeat PQQ_3 PF13570.6 OQR81498.1 - 0.011 16.2 3.4 0.55 10.8 0.0 3.9 4 0 0 4 4 4 0 PQQ-like domain ANAPC4_WD40 PF12894.7 OQR81498.1 - 0.067 13.5 0.0 6 7.2 0.0 3.5 3 1 1 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 OQR81498.1 - 0.17 11.7 0.0 1 9.2 0.0 2.1 1 1 1 2 2 2 0 Eukaryotic translation initiation factor eIF2A Ala_racemase_N PF01168.20 OQR81499.1 - 7.2e-26 91.2 0.2 9.2e-26 90.8 0.2 1.1 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain D-ser_dehydrat PF14031.6 OQR81499.1 - 6.2e-17 62.0 0.0 8.2e-16 58.5 0.0 2.5 2 1 0 2 2 2 1 Putative serine dehydratase domain Mito_carr PF00153.27 OQR81500.1 - 6.4e-31 106.2 7.7 1.5e-13 50.4 0.1 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein Asp PF00026.23 OQR81502.1 - 9.5e-34 117.2 10.4 4.8e-33 114.9 10.4 1.8 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 OQR81502.1 - 2.5e-06 27.8 5.5 0.022 15.0 0.9 2.4 1 1 1 2 2 2 2 Xylanase inhibitor N-terminal gag-asp_proteas PF13975.6 OQR81502.1 - 0.03 14.9 0.2 0.5 11.0 0.1 2.6 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease SNF2_N PF00176.23 OQR81503.1 - 3.7e-62 210.1 0.3 9e-62 208.8 0.3 1.5 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 OQR81503.1 - 4.3e-18 65.7 0.0 1.8e-17 63.7 0.0 2.2 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Chromo PF00385.24 OQR81503.1 - 1.7e-16 59.9 0.0 3.2e-09 36.6 0.1 3.0 3 0 0 3 3 3 2 Chromo (CHRromatin Organisation MOdifier) domain ResIII PF04851.15 OQR81503.1 - 4e-09 36.7 0.0 1.2e-08 35.1 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 OQR81503.1 - 1.6e-06 27.5 0.2 3.7e-06 26.3 0.2 1.5 1 0 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 QLQ PF08880.11 OQR81503.1 - 1.9e-06 27.5 0.6 1.6e-05 24.6 0.0 2.5 2 0 0 2 2 2 1 QLQ PDZ_6 PF17820.1 OQR81503.1 - 0.00032 20.5 0.0 0.00071 19.4 0.0 1.7 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 OQR81503.1 - 0.0022 18.3 0.2 0.078 13.3 0.0 2.8 3 0 0 3 3 3 1 PDZ domain DEAD PF00270.29 OQR81503.1 - 0.0039 17.0 0.0 0.012 15.4 0.0 1.8 1 1 0 1 1 1 1 DEAD/DEAH box helicase PDZ PF00595.24 OQR81503.1 - 0.055 13.8 0.1 0.15 12.5 0.1 1.6 1 0 0 1 1 1 0 PDZ domain VIR_N PF15912.5 OQR81503.1 - 0.53 9.8 5.8 1.2 8.7 5.8 1.5 1 0 0 1 1 1 0 Virilizer, N-terminal Asp PF00026.23 OQR81504.1 - 1.3e-31 110.2 7.3 6.5e-31 107.9 7.3 1.8 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 OQR81504.1 - 0.0034 17.6 8.7 0.48 10.6 0.8 2.6 2 1 1 3 3 3 2 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 OQR81504.1 - 0.076 13.7 0.1 1.2 9.8 0.0 2.6 2 1 0 2 2 2 0 Aspartyl protease FeoA PF04023.14 OQR81505.1 - 0.084 13.1 0.0 0.17 12.2 0.0 1.4 1 0 0 1 1 1 0 FeoA domain DnaJ PF00226.31 OQR81507.1 - 4.1e-13 49.3 0.8 4.1e-13 49.3 0.8 3.2 3 0 0 3 3 3 1 DnaJ domain Macoilin PF09726.9 OQR81507.1 - 0.57 8.7 16.7 0.9 8.0 16.7 1.2 1 0 0 1 1 1 0 Macoilin family Fe_hyd_lg_C PF02906.14 OQR81507.1 - 0.97 9.0 5.5 2.9 7.5 5.5 1.8 1 1 0 1 1 1 0 Iron only hydrogenase large subunit, C-terminal domain MAT1 PF06391.13 OQR81507.1 - 4.9 6.9 24.5 0.27 11.0 18.6 1.8 2 0 0 2 2 2 0 CDK-activating kinase assembly factor MAT1 V_ATPase_I PF01496.19 OQR81507.1 - 5.5 4.8 8.8 7.6 4.3 8.8 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family ISG65-75 PF11727.8 OQR81507.1 - 7.9 5.6 30.5 6.2 6.0 8.2 2.7 2 1 1 3 3 3 0 Invariant surface glycoprotein DUF842 PF05811.13 OQR81508.1 - 2.8e-42 143.5 15.3 3.1e-42 143.4 15.3 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF842) DUF4635 PF15466.6 OQR81508.1 - 0.0088 15.6 0.8 0.015 14.8 0.8 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4635) zf-Tim10_DDP PF02953.15 OQR81508.1 - 0.019 14.6 8.0 0.62 9.8 2.6 2.6 1 1 1 2 2 2 0 Tim10/DDP family zinc finger Exonuc_VII_L PF02601.15 OQR81508.1 - 0.024 14.2 3.0 0.026 14.1 3.0 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit HD_3 PF13023.6 OQR81508.1 - 0.082 12.8 1.1 0.12 12.3 0.4 1.6 1 1 0 2 2 2 0 HD domain ApoLp-III PF07464.11 OQR81508.1 - 0.082 13.0 2.5 0.27 11.3 1.0 2.0 1 1 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) Col_cuticle_N PF01484.17 OQR81508.1 - 0.083 13.0 2.8 0.21 11.6 0.4 2.3 2 0 0 2 2 2 0 Nematode cuticle collagen N-terminal domain ING PF12998.7 OQR81508.1 - 0.092 13.3 2.6 4.6 7.9 0.1 2.4 1 1 1 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding PSD1 PF07587.11 OQR81508.1 - 0.22 11.0 2.7 0.26 10.7 2.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1553) COMPASS-Shg1 PF05205.12 OQR81508.1 - 0.22 12.2 2.0 1.4 9.7 1.1 2.0 1 1 1 2 2 2 0 COMPASS (Complex proteins associated with Set1p) component shg1 DHHC PF01529.20 OQR81509.1 - 0.026 14.6 1.7 0.029 14.5 1.7 1.1 1 0 0 1 1 1 0 DHHC palmitoyltransferase Ribosomal_S6e PF01092.19 OQR81510.1 - 4.9e-58 194.5 0.1 4.9e-58 194.5 0.1 1.6 2 0 0 2 2 2 1 Ribosomal protein S6e Phage_antitermQ PF06530.12 OQR81511.1 - 0.0048 16.8 4.4 0.98 9.3 0.4 2.7 2 0 0 2 2 2 2 Phage antitermination protein Q IFP_35_N PF07334.13 OQR81511.1 - 7.4 6.7 11.4 6.2 7.0 0.2 4.1 3 1 0 3 3 3 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus AFG1_ATPase PF03969.16 OQR81513.1 - 1.5e-89 300.4 2.1 1.2e-87 294.2 0.4 2.3 2 0 0 2 2 2 2 AFG1-like ATPase AAA_22 PF13401.6 OQR81513.1 - 2.5e-05 24.6 0.0 8.2e-05 22.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 OQR81513.1 - 5.6e-05 23.6 0.0 0.00036 20.9 0.0 2.4 1 1 0 1 1 1 1 AAA ATPase domain TPR_19 PF14559.6 OQR81513.1 - 0.00054 20.4 2.8 0.44 11.1 0.2 4.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.6 OQR81513.1 - 0.002 18.4 0.4 0.37 11.1 0.0 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 OQR81513.1 - 0.0047 17.6 1.5 3.8 8.6 0.0 4.5 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.17 OQR81513.1 - 0.0062 16.6 2.6 0.15 12.2 0.0 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat ATPase_2 PF01637.18 OQR81513.1 - 0.023 14.6 0.2 0.15 11.9 0.1 2.4 2 1 0 2 2 2 0 ATPase domain predominantly from Archaea AAA_14 PF13173.6 OQR81513.1 - 0.036 14.1 0.0 0.16 12.0 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 OQR81513.1 - 0.036 14.5 0.0 0.13 12.7 0.0 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Keratin_2_head PF16208.5 OQR81513.1 - 0.084 13.0 5.3 0.16 12.1 5.3 1.3 1 0 0 1 1 1 0 Keratin type II head KRTAP PF11759.8 OQR81513.1 - 0.79 10.3 8.3 1.8 9.2 8.3 1.5 1 0 0 1 1 1 0 Keratin-associated matrix DUF1422 PF07226.11 OQR81513.1 - 2.2 8.3 5.4 1.6 8.7 2.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1422) Thaumatin PF00314.17 OQR81514.1 - 0.00074 19.2 4.7 0.017 14.8 0.7 3.2 2 1 1 3 3 3 3 Thaumatin family SOG2 PF10428.9 OQR81514.1 - 0.082 12.1 9.4 0.089 12.0 9.4 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein EF-hand_1 PF00036.32 OQR81515.1 - 0.0091 15.5 0.0 0.024 14.2 0.0 1.7 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.6 OQR81515.1 - 0.028 14.9 0.0 0.094 13.2 0.0 1.9 1 0 0 1 1 1 0 EF-hand domain pair EF-hand_8 PF13833.6 OQR81515.1 - 0.043 13.7 0.0 0.094 12.6 0.0 1.5 1 0 0 1 1 1 0 EF-hand domain pair TRAPPC-Trs85 PF12739.7 OQR81516.1 - 1e-69 235.5 4.3 2.6e-69 234.2 4.3 1.6 1 1 0 1 1 1 1 ER-Golgi trafficking TRAPP I complex 85 kDa subunit TRAPPC9-Trs120 PF08626.11 OQR81516.1 - 0.002 15.6 0.0 0.0053 14.2 0.0 1.6 2 0 0 2 2 2 1 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit Transglut_C PF00927.22 OQR81516.1 - 0.022 14.9 0.0 13 6.0 0.0 2.7 2 0 0 2 2 2 0 Transglutaminase family, C-terminal ig like domain Orexin_rec2 PF03827.13 OQR81517.1 - 1.6 8.8 4.1 17 5.5 0.0 3.2 3 0 0 3 3 3 0 Orexin receptor type 2 Asp_Arg_Hydrox PF05118.15 OQR81518.1 - 1.3e-09 38.0 0.1 2.3e-09 37.2 0.1 1.4 1 0 0 1 1 1 1 Aspartyl/Asparaginyl beta-hydroxylase Sulfotransfer_1 PF00685.27 OQR81518.1 - 8.4e-09 35.3 0.0 4.7e-08 32.8 0.0 2.1 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 OQR81518.1 - 4.5e-07 30.5 0.0 0.0091 16.4 0.0 2.8 2 1 1 3 3 3 2 Sulfotransferase family Sulfotransfer_2 PF03567.14 OQR81518.1 - 0.0007 19.6 0.0 0.001 19.0 0.0 1.2 1 0 0 1 1 1 1 Sulfotransferase family C2 PF00168.30 OQR81519.1 - 0.0011 19.3 0.1 0.0077 16.5 0.0 2.3 2 0 0 2 2 2 1 C2 domain TUDOR_5 PF18359.1 OQR81519.1 - 0.0017 18.0 0.4 0.0052 16.5 0.1 2.1 2 0 0 2 2 2 1 Histone methyltransferase Tudor domain 1 DUF3333 PF11812.8 OQR81519.1 - 0.15 12.3 6.3 0.072 13.3 3.3 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF3333) PDZ PF00595.24 OQR81520.1 - 4.5e-06 26.9 0.0 0.38 11.1 0.0 3.2 3 0 0 3 3 3 3 PDZ domain PDZ_6 PF17820.1 OQR81520.1 - 1.2e-05 25.1 0.0 1.7 8.6 0.0 3.3 3 0 0 3 3 3 3 PDZ domain DUF202 PF02656.15 OQR81521.1 - 0.011 16.1 1.6 0.018 15.5 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF202) DUF3811 PF11656.8 OQR81521.1 - 0.1 13.0 2.1 0.15 12.5 2.1 1.3 1 0 0 1 1 1 0 YjbD family (DUF3811) Ank_2 PF12796.7 OQR81522.1 - 3.3e-33 114.1 7.3 5.9e-08 33.2 0.1 5.0 3 1 2 5 5 5 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQR81522.1 - 1.2e-28 99.1 8.6 5.8e-12 45.9 0.3 6.5 4 3 4 8 8 8 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQR81522.1 - 2.6e-28 94.9 11.1 1.3e-05 25.2 0.0 9.5 9 1 1 10 10 10 6 Ankyrin repeat Ank PF00023.30 OQR81522.1 - 5.5e-22 77.2 16.2 1.6e-05 25.1 0.1 8.4 9 0 0 9 9 9 5 Ankyrin repeat Ank_5 PF13857.6 OQR81522.1 - 6.2e-19 67.8 13.0 2.7e-06 27.5 0.2 8.0 3 2 5 9 9 9 5 Ankyrin repeats (many copies) Mic1 PF07035.12 OQR81522.1 - 0.017 14.8 0.8 0.033 13.9 0.8 1.4 1 0 0 1 1 1 0 Colon cancer-associated protein Mic1-like Aft1_HRA PF11786.8 OQR81522.1 - 0.11 12.8 0.1 0.25 11.7 0.1 1.5 1 0 0 1 1 1 0 Aft1 HRA domain Peptidase_S28 PF05577.12 OQR81524.1 - 3e-71 240.5 1.0 9e-71 238.9 1.0 1.7 1 1 0 1 1 1 1 Serine carboxypeptidase S28 L51_S25_CI-B8 PF05047.16 OQR81524.1 - 8.5e-10 38.4 0.2 1.6e-09 37.5 0.2 1.5 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain DUF2920 PF11144.8 OQR81524.1 - 0.12 11.5 0.2 0.67 9.1 0.1 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF2920) Ribosomal_L33 PF00471.20 OQR81525.1 - 8.5e-15 54.9 0.0 1e-14 54.7 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L33 Reo_P9 PF06043.11 OQR81525.1 - 0.096 12.1 0.0 0.1 12.0 0.0 1.0 1 0 0 1 1 1 0 Reovirus P9-like family Pkinase PF00069.25 OQR81526.1 - 4.5e-79 265.5 0.0 6.6e-79 265.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQR81526.1 - 1.9e-35 122.4 0.0 3e-35 121.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase OGG_N PF07934.12 OQR81526.1 - 1.2e-20 73.9 0.0 2.2e-20 72.9 0.0 1.5 1 0 0 1 1 1 1 8-oxoguanine DNA glycosylase, N-terminal domain HhH-GPD PF00730.25 OQR81526.1 - 7.3e-18 65.0 0.0 1.8e-17 63.8 0.0 1.6 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein Kinase-like PF14531.6 OQR81526.1 - 1.5e-05 24.4 0.0 0.001 18.4 0.0 2.2 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 OQR81526.1 - 0.00016 21.1 0.1 0.00034 20.0 0.1 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OQR81526.1 - 0.003 17.5 0.0 1.3 8.9 0.0 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family Elf4 PF07011.11 OQR81526.1 - 0.17 11.8 0.4 4.8 7.2 0.0 2.6 2 0 0 2 2 2 0 Early Flowering 4 domain DUF4407 PF14362.6 OQR81527.1 - 0.16 11.3 12.2 0.33 10.2 11.8 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) YlqD PF11068.8 OQR81527.1 - 0.69 10.3 25.9 0.52 10.7 4.7 2.5 1 1 1 2 2 2 0 YlqD protein Myb_DNA-bind_3 PF12776.7 OQR81527.1 - 0.77 10.8 7.3 0.45 11.5 0.7 2.6 2 1 1 3 3 3 0 Myb/SANT-like DNA-binding domain Tup_N PF08581.10 OQR81527.1 - 1.9 8.9 21.1 0.85 10.0 2.9 3.8 1 1 2 3 3 3 0 Tup N-terminal UPF0242 PF06785.11 OQR81527.1 - 6 6.9 28.5 3e+02 1.4 26.5 2.5 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DIT1_PvcA PF05141.12 OQR81527.1 - 6.6 6.1 11.9 0.7 9.3 0.2 2.2 1 1 1 2 2 2 0 Pyoverdine/dityrosine biosynthesis protein FYVE PF01363.21 OQR81528.1 - 9.2e-18 64.2 8.9 1.7e-17 63.3 8.9 1.4 1 0 0 1 1 1 1 FYVE zinc finger GAF PF01590.26 OQR81528.1 - 7.1e-05 23.4 0.0 0.00022 21.8 0.0 1.8 2 0 0 2 2 2 1 GAF domain FYVE_2 PF02318.16 OQR81528.1 - 0.034 14.4 5.8 0.075 13.3 5.8 1.5 1 0 0 1 1 1 0 FYVE-type zinc finger DUF4428 PF14471.6 OQR81528.1 - 0.069 13.1 2.3 0.19 11.7 2.3 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4428) C1_2 PF03107.16 OQR81528.1 - 6.1 7.3 10.1 2.4 8.5 7.2 1.9 2 0 0 2 2 2 0 C1 domain ACOX PF01756.19 OQR81530.1 - 7.1e-33 113.7 0.7 1.6e-32 112.6 0.3 1.8 2 0 0 2 2 2 1 Acyl-CoA oxidase Acyl-CoA_dh_M PF02770.19 OQR81530.1 - 2.4e-15 56.5 0.1 5.8e-15 55.3 0.1 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_ox_N PF14749.6 OQR81530.1 - 2.2e-11 44.4 0.2 3.9e-11 43.6 0.2 1.4 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_1 PF00441.24 OQR81530.1 - 0.00013 22.2 0.0 0.00033 20.9 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 OQR81530.1 - 0.015 16.0 0.0 0.064 13.9 0.0 2.1 2 0 0 2 2 2 0 Acyl-CoA dehydrogenase, N-terminal domain F-box-like PF12937.7 OQR81531.1 - 0.00028 20.7 0.0 0.18 11.8 0.0 2.7 2 0 0 2 2 2 2 F-box-like F-box PF00646.33 OQR81531.1 - 0.0023 17.8 3.3 0.4 10.6 0.2 3.0 3 0 0 3 3 3 2 F-box domain LRR_8 PF13855.6 OQR81531.1 - 1.5 8.7 8.7 32 4.4 0.0 5.0 6 0 0 6 6 6 0 Leucine rich repeat LRR_6 PF13516.6 OQR81531.1 - 1.9 8.7 9.0 3.2 8.1 0.0 5.3 8 0 0 8 8 8 0 Leucine Rich repeat DcpS_C PF11969.8 OQR81532.1 - 2.7e-16 60.1 4.1 3.9e-16 59.5 4.1 1.2 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding HIT PF01230.23 OQR81532.1 - 5.5e-10 39.9 4.7 1.1e-09 38.9 4.7 1.5 1 1 0 1 1 1 1 HIT domain Thioredoxin PF00085.20 OQR81533.1 - 5.7e-08 32.7 0.0 0.0031 17.5 0.0 2.9 3 0 0 3 3 3 2 Thioredoxin Thioredoxin_2 PF13098.6 OQR81533.1 - 0.019 15.4 2.2 9.4 6.7 0.3 3.6 3 1 0 3 3 3 0 Thioredoxin-like domain YacG PF03884.14 OQR81533.1 - 0.2 11.4 0.8 0.35 10.6 0.8 1.4 1 0 0 1 1 1 0 DNA gyrase inhibitor YacG DUF4498 PF14926.6 OQR81534.1 - 4.7e-59 199.7 0.0 5.2e-59 199.5 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4498) Apolipoprotein PF01442.18 OQR81535.1 - 8.3e-06 25.8 1.6 8.3e-06 25.8 1.6 13.1 6 4 8 14 14 14 7 Apolipoprotein A1/A4/E domain Rnk_N PF14760.6 OQR81535.1 - 0.14 12.7 0.8 2.3 8.8 0.4 3.1 2 0 0 2 2 2 0 Rnk N-terminus Ank_2 PF12796.7 OQR81536.1 - 1.5e-31 108.8 21.0 9.8e-09 35.7 0.8 5.1 1 1 6 7 7 7 7 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OQR81536.1 - 5.8e-24 83.8 12.5 0.019 15.3 0.1 9.4 1 1 7 9 9 9 8 Ankyrin repeats (many copies) Ank_4 PF13637.6 OQR81536.1 - 8.3e-21 74.1 11.5 0.00035 21.1 0.3 7.1 2 1 5 8 8 8 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQR81536.1 - 2.7e-13 48.8 3.8 0.46 11.2 0.0 8.8 11 0 0 11 11 11 2 Ankyrin repeat DUF5049 PF16468.5 OQR81536.1 - 7.2e-08 32.2 0.3 4.1 7.4 0.0 6.6 3 2 4 7 7 7 2 Domain of unknown function (DUF5049) Ank PF00023.30 OQR81536.1 - 0.0002 21.7 5.3 28 5.4 0.2 6.6 6 1 0 6 6 6 0 Ankyrin repeat DUF3953 PF13129.6 OQR81536.1 - 0.006 16.3 0.0 9.3 6.1 0.0 3.9 4 0 0 4 4 4 1 Protein of unknown function (DUF3953) GFA PF04828.14 OQR81537.1 - 0.00015 22.0 0.1 0.00052 20.3 0.0 1.9 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme Ribosomal_L37e PF01907.19 OQR81537.1 - 0.1 12.7 0.6 0.1 12.7 0.6 1.9 2 0 0 2 2 2 0 Ribosomal protein L37e MIF4G PF02854.19 OQR81538.1 - 2.6e-46 157.9 4.0 1.4e-31 109.8 1.5 2.4 2 0 0 2 2 2 2 MIF4G domain MA3 PF02847.17 OQR81538.1 - 2e-06 27.7 0.0 2e-05 24.6 0.0 2.6 2 0 0 2 2 2 1 MA3 domain Arm PF00514.23 OQR81539.1 - 2.5e-17 62.2 22.6 0.00084 19.3 0.1 10.7 10 0 0 10 10 10 6 Armadillo/beta-catenin-like repeat KAP PF05804.12 OQR81539.1 - 0.0012 17.2 20.1 0.047 11.8 0.2 4.5 4 1 0 4 4 4 4 Kinesin-associated protein (KAP) RICTOR_V PF14668.6 OQR81539.1 - 0.0034 17.6 6.6 2.7 8.3 0.0 5.6 5 1 1 6 6 6 1 Rapamycin-insensitive companion of mTOR, domain 5 Vac14_Fab1_bd PF12755.7 OQR81539.1 - 0.0052 17.4 5.4 0.097 13.3 0.1 5.1 4 1 1 5 5 5 1 Vacuolar 14 Fab1-binding region V-ATPase_H_N PF03224.14 OQR81539.1 - 0.17 11.1 18.6 2.3 7.4 0.5 6.1 2 1 2 4 4 4 0 V-ATPase subunit H Cnd1 PF12717.7 OQR81539.1 - 1 9.4 18.9 0.45 10.5 0.4 5.9 5 2 3 8 8 8 0 non-SMC mitotic condensation complex subunit 1 RICTOR_M PF14666.6 OQR81539.1 - 2.4 8.0 8.7 1.4 8.7 0.2 4.0 3 1 0 4 4 4 0 Rapamycin-insensitive companion of mTOR, middle domain HUN PF08729.10 OQR81540.1 - 1.2e-10 41.2 4.2 3.6e-10 39.7 4.2 1.8 1 0 0 1 1 1 1 HPC2 and ubinuclein domain UBN_AB PF14075.6 OQR81540.1 - 0.0071 16.1 0.0 0.0071 16.1 0.0 2.6 3 0 0 3 3 3 1 Ubinuclein conserved middle domain DUF373 PF04123.13 OQR81541.1 - 0.14 11.6 2.3 7.5 5.9 0.2 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF373) Tetraspanin PF00335.20 OQR81541.1 - 8.4 6.0 15.3 0.081 12.6 2.6 2.1 1 1 1 2 2 2 0 Tetraspanin family C2 PF00168.30 OQR81542.1 - 2e-16 60.2 0.0 2.6e-16 59.8 0.0 1.2 1 0 0 1 1 1 1 C2 domain DUF2076 PF09849.9 OQR81542.1 - 0.0015 18.7 1.8 0.0018 18.4 1.8 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2076) Pkinase_Tyr PF07714.17 OQR81543.1 - 2e-52 178.1 0.0 2.7e-52 177.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OQR81543.1 - 7.6e-48 163.2 0.0 1.2e-47 162.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain PB1 PF00564.24 OQR81543.1 - 9.5e-13 47.9 0.0 2.3e-12 46.7 0.0 1.6 1 0 0 1 1 1 1 PB1 domain Pkinase_fungal PF17667.1 OQR81543.1 - 9.5e-06 24.6 0.0 1.5e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 OQR81543.1 - 0.0041 16.5 0.0 0.0072 15.7 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 OQR81543.1 - 0.0042 16.5 0.0 0.0069 15.8 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family UQ_con PF00179.26 OQR81543.1 - 0.046 13.4 0.0 0.097 12.3 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin-conjugating enzyme Haspin_kinase PF12330.8 OQR81543.1 - 0.11 11.4 0.5 0.86 8.5 0.0 2.0 2 0 0 2 2 2 0 Haspin like kinase domain Peptidase_C2 PF00648.21 OQR81544.1 - 2.5e-08 33.3 0.0 1e-07 31.3 0.0 1.9 2 0 0 2 2 2 1 Calpain family cysteine protease DUF4097 PF13349.6 OQR81545.1 - 3.5e-08 33.1 13.8 9.5e-07 28.4 13.9 2.6 1 1 0 1 1 1 1 Putative adhesin LRR_4 PF12799.7 OQR81545.1 - 1.7e-07 31.4 22.0 2.3e-05 24.7 5.8 4.3 4 1 1 5 5 5 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 OQR81545.1 - 3.3e-05 23.6 13.4 0.0086 15.8 8.0 3.2 2 1 0 2 2 2 2 Leucine rich repeat LRR_6 PF13516.6 OQR81545.1 - 0.00034 20.4 8.6 0.24 11.5 0.5 4.0 3 0 0 3 3 3 2 Leucine Rich repeat Tetraspanin PF00335.20 OQR81545.1 - 0.0055 16.4 18.3 0.0055 16.4 18.3 4.7 2 1 3 5 5 5 1 Tetraspanin family DUF3185 PF11381.8 OQR81545.1 - 0.032 14.3 10.2 0.97 9.5 0.2 4.4 4 0 0 4 4 4 0 Protein of unknown function (DUF3185) LRR_1 PF00560.33 OQR81545.1 - 0.057 14.0 5.1 9.5 7.2 1.0 4.3 3 0 0 3 3 3 0 Leucine Rich Repeat C2 PF00168.30 OQR81546.1 - 2.3e-14 53.5 0.0 3.2e-14 53.0 0.0 1.2 1 0 0 1 1 1 1 C2 domain ATP_sub_h PF10775.9 OQR81546.1 - 0.024 14.6 0.5 0.05 13.6 0.5 1.5 1 0 0 1 1 1 0 ATP synthase complex subunit h C2 PF00168.30 OQR81547.1 - 1.9e-24 85.9 0.0 3.5e-24 85.0 0.0 1.4 1 0 0 1 1 1 1 C2 domain EMC3_TMCO1 PF01956.16 OQR81547.1 - 0.067 12.9 11.5 0.1 12.3 11.5 1.2 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like DUF4407 PF14362.6 OQR81547.1 - 0.39 10.0 16.0 0.56 9.5 16.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) ABC2_membrane_2 PF12679.7 OQR81547.1 - 0.42 9.9 1.6 0.54 9.5 1.6 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein AUX_IAA PF02309.16 OQR81547.1 - 0.49 10.2 8.9 0.88 9.4 8.9 1.3 1 0 0 1 1 1 0 AUX/IAA family GREB1 PF15782.5 OQR81547.1 - 1.1 6.3 9.7 1.3 6.0 9.7 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer CPSF100_C PF13299.6 OQR81547.1 - 1.4 9.0 5.5 2.1 8.5 5.5 1.2 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Neur_chan_memb PF02932.16 OQR81547.1 - 2.4 8.2 5.8 3 7.9 5.8 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region TFIIA PF03153.13 OQR81547.1 - 4.3 7.2 54.6 5.5 6.9 54.6 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF4883 PF16224.5 OQR81547.1 - 4.7 7.5 6.3 0.36 11.1 0.5 1.8 2 0 0 2 2 2 0 DOmain of unknown function (DUF4883) Exonuc_VII_L PF02601.15 OQR81547.1 - 7.2 6.1 15.7 10 5.6 15.7 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF4200 PF13863.6 OQR81548.1 - 1.3e-34 119.2 22.2 1.3e-34 119.2 22.2 5.2 5 0 0 5 5 5 2 Domain of unknown function (DUF4200) DUF3800 PF12686.7 OQR81548.1 - 2.1 9.0 10.3 1.3e+03 0.0 10.5 3.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3800) 2OG-FeII_Oxy_3 PF13640.6 OQR81549.1 - 1.6e-17 64.1 0.0 2.7e-17 63.4 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.6 OQR81549.1 - 7.4e-08 33.0 0.0 1.5e-07 32.0 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Mg_trans_NIPA PF05653.14 OQR81550.1 - 6.3e-30 104.3 20.5 7.5e-30 104.1 20.5 1.0 1 0 0 1 1 1 1 Magnesium transporter NIPA WBP-1 PF11669.8 OQR81550.1 - 0.073 13.7 0.5 0.073 13.7 0.5 2.5 3 0 0 3 3 3 0 WW domain-binding protein 1 zf-CCHC PF00098.23 OQR81551.1 - 2.2e-14 52.8 41.9 0.00041 20.3 0.3 5.3 5 0 0 5 5 5 5 Zinc knuckle zf-CCHC_2 PF13696.6 OQR81551.1 - 0.0014 18.4 5.3 0.031 14.1 1.8 5.2 5 0 0 5 5 5 3 Zinc knuckle zf-CCHC_4 PF14392.6 OQR81551.1 - 0.0077 15.9 32.6 0.32 10.7 1.0 5.2 4 1 1 5 5 5 3 Zinc knuckle zf-CCHC_3 PF13917.6 OQR81551.1 - 1.9 8.5 25.5 1.5 8.8 0.8 4.6 1 1 3 4 4 4 0 Zinc knuckle Sin_N PF04801.13 OQR81551.1 - 2.3 7.3 6.9 0.13 11.4 0.7 1.8 2 0 0 2 2 2 0 Sin-like protein conserved region FAM184 PF15665.5 OQR81552.1 - 0.15 11.9 24.6 0.22 11.3 24.6 1.2 1 0 0 1 1 1 0 Family with sequence similarity 184, A and B GAS PF13851.6 OQR81552.1 - 0.46 9.8 31.2 0.13 11.5 15.5 2.1 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Exonuc_VII_L PF02601.15 OQR81552.1 - 1.1 8.8 15.1 1.6 8.2 15.1 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit NPV_P10 PF05531.12 OQR81552.1 - 1.2 9.6 7.1 2.7 8.5 0.3 2.5 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein SlyX PF04102.12 OQR81552.1 - 2.2 8.9 16.5 0.079 13.6 3.9 2.8 2 1 0 2 2 2 0 SlyX CpxA_peri PF16527.5 OQR81552.1 - 6.2 7.2 12.9 6.1 7.2 4.2 2.1 1 1 1 2 2 2 0 Two-component sensor protein CpxA, periplasmic domain WD40 PF00400.32 OQR81553.1 - 1.1e-31 108.4 30.3 5.6e-05 23.8 0.2 11.3 11 0 0 11 11 11 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OQR81553.1 - 2.7e-17 62.8 10.6 0.014 15.7 0.1 9.2 2 1 6 9 9 9 5 Anaphase-promoting complex subunit 4 WD40 domain BBS2_Mid PF14783.6 OQR81553.1 - 5.5e-05 23.2 0.2 0.17 11.9 0.1 4.3 5 1 1 6 6 6 2 Ciliary BBSome complex subunit 2, middle region Hira PF07569.11 OQR81553.1 - 0.015 15.0 8.5 0.17 11.6 0.1 5.2 4 2 2 6 6 6 0 TUP1-like enhancer of split Nup160 PF11715.8 OQR81553.1 - 0.015 14.0 12.4 0.075 11.7 0.1 4.3 6 0 0 6 6 6 0 Nucleoporin Nup120/160 Post_transc_reg PF13797.6 OQR81554.1 - 0.085 12.7 0.1 0.14 12.0 0.1 1.5 1 0 0 1 1 1 0 Post-transcriptional regulator Neurexophilin PF06312.12 OQR81554.1 - 0.13 11.7 0.0 0.17 11.3 0.0 1.1 1 0 0 1 1 1 0 Neurexophilin CD34_antigen PF06365.12 OQR81555.1 - 0.01 15.4 0.0 0.019 14.5 0.0 1.4 1 0 0 1 1 1 0 CD34/Podocalyxin family Glycophorin_A PF01102.18 OQR81555.1 - 0.031 14.5 0.0 0.059 13.6 0.0 1.5 1 0 0 1 1 1 0 Glycophorin A EphA2_TM PF14575.6 OQR81555.1 - 0.04 14.8 0.0 0.062 14.2 0.0 1.5 1 1 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF4448 PF14610.6 OQR81555.1 - 0.057 13.2 0.0 0.095 12.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) Adeno_E3_CR2 PF02439.15 OQR81555.1 - 0.084 12.6 1.1 0.13 12.1 1.1 1.2 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 LapA_dom PF06305.11 OQR81555.1 - 0.6 10.0 1.9 0.41 10.5 0.3 1.5 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain Vps51 PF08700.11 OQR81556.1 - 5.8e-14 51.9 1.5 2e-13 50.2 1.5 2.0 1 0 0 1 1 1 1 Vps51/Vps67 Exo84_C PF16528.5 OQR81556.1 - 9.8e-12 45.1 3.0 1.5e-11 44.5 0.8 2.3 1 1 1 2 2 2 1 Exocyst component 84 C-terminal PH PF00169.29 OQR81556.1 - 1e-10 42.0 0.0 2.8e-10 40.6 0.0 1.8 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 OQR81556.1 - 6.6e-05 23.3 0.1 0.0003 21.2 0.0 2.2 2 0 0 2 2 2 1 Pleckstrin homology domain COG5 PF10392.9 OQR81556.1 - 0.00085 19.5 0.7 0.0037 17.4 0.7 2.1 1 0 0 1 1 1 1 Golgi transport complex subunit 5 DEP PF00610.21 OQR81556.1 - 0.019 15.0 0.0 0.057 13.5 0.0 1.8 1 0 0 1 1 1 0 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) COG2 PF06148.11 OQR81556.1 - 0.023 14.8 0.2 0.078 13.1 0.1 2.0 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 PH_8 PF15409.6 OQR81556.1 - 0.035 14.4 0.0 0.79 10.0 0.0 2.7 2 0 0 2 2 2 0 Pleckstrin homology domain NYD-SP28 PF14772.6 OQR81556.1 - 0.056 13.5 0.4 0.2 11.7 0.4 2.0 1 0 0 1 1 1 0 Sperm tail PKD_channel PF08016.12 OQR81558.1 - 3.6e-47 161.0 14.9 3.6e-47 161.0 14.9 1.7 2 0 0 2 2 2 1 Polycystin cation channel Ion_trans PF00520.31 OQR81558.1 - 1.2e-12 47.6 25.4 1.2e-12 47.6 25.4 2.2 2 0 0 2 2 2 1 Ion transport protein DUF5345 PF17280.2 OQR81558.1 - 1.8 8.6 5.4 0.59 10.2 0.1 2.7 2 0 0 2 2 2 0 Family of unknown function (DUF5345) LRR_9 PF14580.6 OQR81560.1 - 3.1e-10 39.8 0.1 1.8e-09 37.3 0.1 2.4 1 0 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.7 OQR81560.1 - 8.9e-05 22.8 6.5 0.00018 21.8 2.1 3.7 2 1 2 4 4 3 1 Leucine Rich repeats (2 copies) GIT_CC PF16559.5 OQR81560.1 - 0.0013 18.6 1.4 0.0013 18.6 1.4 6.9 6 0 0 6 6 6 2 GIT coiled-coil Rho guanine nucleotide exchange factor LRR_8 PF13855.6 OQR81560.1 - 0.11 12.2 6.0 0.047 13.4 2.2 2.4 2 0 0 2 2 2 0 Leucine rich repeat Ank_4 PF13637.6 OQR81561.1 - 1.2e-29 102.3 2.1 1e-10 41.9 0.1 3.3 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 OQR81561.1 - 1.5e-28 99.2 4.8 3.4e-14 53.2 1.1 2.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 OQR81561.1 - 1.3e-25 88.6 4.4 1.2e-05 25.5 0.0 4.1 4 0 0 4 4 4 4 Ankyrin repeat Ank_3 PF13606.6 OQR81561.1 - 2e-23 79.9 0.6 1.2e-05 25.3 0.0 4.1 4 0 0 4 4 4 4 Ankyrin repeat Ank_5 PF13857.6 OQR81561.1 - 7.4e-20 70.8 1.3 1.1e-08 35.2 0.1 3.3 1 1 2 3 3 3 3 Ankyrin repeats (many copies) T6SS-SciN PF12790.7 OQR81561.1 - 0.022 14.5 0.5 2.9 7.6 0.0 3.3 4 0 0 4 4 4 0 Type VI secretion lipoprotein, VasD, EvfM, TssJ, VC_A0113 Imm_superinfect PF14373.6 OQR81561.1 - 0.07 13.1 0.4 80 3.3 0.0 3.8 4 0 0 4 4 4 0 Superinfection immunity protein Cyclin_N PF00134.23 OQR81563.1 - 9.1e-08 31.9 1.4 1.4e-07 31.3 1.4 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain Astro_capsid_p PF12226.8 OQR81563.1 - 0.57 9.3 3.5 0.83 8.7 3.5 1.1 1 0 0 1 1 1 0 Turkey astrovirus capsid protein CENP-B_dimeris PF09026.10 OQR81563.1 - 0.91 10.0 7.0 2.1 8.8 7.0 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Ion_trans PF00520.31 OQR81564.1 - 4e-46 157.2 42.6 1.9e-24 86.2 17.5 2.3 2 0 0 2 2 2 2 Ion transport protein Ion_trans_2 PF07885.16 OQR81564.1 - 2.4e-23 81.9 20.9 4e-13 49.1 9.6 3.3 2 1 0 2 2 2 2 Ion channel cNMP_binding PF00027.29 OQR81564.1 - 1.3e-16 60.4 0.1 4.7e-07 29.8 0.0 3.1 3 0 0 3 3 3 2 Cyclic nucleotide-binding domain IRK PF01007.20 OQR81564.1 - 0.041 13.7 16.4 0.81 9.5 6.4 2.5 2 0 0 2 2 2 0 Inward rectifier potassium channel transmembrane domain Bromodomain PF00439.25 OQR81566.1 - 8.8e-05 22.5 0.1 0.00021 21.3 0.1 1.7 1 0 0 1 1 1 1 Bromodomain RNA_pol_Rpc4 PF05132.14 OQR81566.1 - 0.011 16.2 0.8 0.016 15.6 0.8 1.2 1 0 0 1 1 1 0 RNA polymerase III RPC4 Med3 PF11593.8 OQR81566.1 - 0.38 9.9 2.9 0.51 9.5 2.9 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal LRR_4 PF12799.7 OQR81567.1 - 0.00015 22.0 5.4 0.04 14.4 1.9 4.5 3 1 2 5 5 5 3 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 OQR81567.1 - 0.002 18.1 9.0 0.98 9.6 0.2 4.9 5 0 0 5 5 5 2 Leucine Rich repeat F-box PF00646.33 OQR81567.1 - 0.081 12.8 0.1 0.26 11.2 0.1 1.9 1 0 0 1 1 1 0 F-box domain Flp_N PF03930.14 OQR81567.1 - 0.093 12.7 0.0 0.3 11.1 0.0 1.8 2 0 0 2 2 2 0 Recombinase Flp protein N-terminus IL4 PF00727.18 OQR81567.1 - 0.12 12.6 1.3 1.1 9.5 0.1 2.4 2 0 0 2 2 2 0 Interleukin 4 DUF2462 PF09495.10 OQR81568.1 - 0.011 16.4 12.1 0.011 16.4 12.1 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2462) Haem_bd PF14376.6 OQR81568.1 - 0.34 10.9 5.1 0.17 11.8 0.7 2.0 2 0 0 2 2 2 0 Haem-binding domain XRN_M PF17846.1 OQR81568.1 - 6.1 5.7 7.9 0.72 8.7 1.0 1.9 1 1 1 2 2 2 0 Xrn1 helical domain LRR_6 PF13516.6 OQR81569.1 - 9.2e-16 56.5 12.9 0.076 13.1 0.1 8.6 8 0 0 8 8 8 7 Leucine Rich repeat LRR_4 PF12799.7 OQR81569.1 - 1.8e-07 31.3 3.8 0.06 13.8 0.1 5.9 5 1 1 6 6 6 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 OQR81569.1 - 1.5e-05 24.9 5.3 80 4.4 0.0 8.2 8 1 0 8 8 8 0 Leucine Rich Repeat SAM_Ste50p PF09235.10 OQR81569.1 - 1 9.7 9.6 6.5 7.1 0.0 5.0 4 2 1 5 5 5 0 Ste50p, sterile alpha motif zf-primase PF09329.11 OQR81571.1 - 0.12 12.2 0.0 0.22 11.3 0.0 1.4 1 0 0 1 1 1 0 Primase zinc finger DUF4085 PF13315.6 OQR81572.1 - 0.027 14.1 0.5 0.59 9.7 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4085) Myb_DNA-binding PF00249.31 OQR81572.1 - 0.044 14.0 2.9 0.26 11.5 0.0 3.0 3 0 0 3 3 3 0 Myb-like DNA-binding domain Cation_ATPase_N PF00690.26 OQR81572.1 - 0.28 10.9 3.4 12 5.7 0.0 3.6 4 0 0 4 4 4 0 Cation transporter/ATPase, N-terminus Glycos_transf_1 PF00534.20 OQR81573.1 - 1.1e-44 152.1 0.0 4.3e-21 75.2 0.0 3.1 2 2 0 2 2 2 2 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 OQR81573.1 - 9.9e-34 116.7 0.2 5.9e-16 59.1 0.0 2.9 3 0 0 3 3 3 2 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 OQR81573.1 - 6.8e-12 45.6 0.0 3.8e-05 24.0 0.0 2.6 2 0 0 2 2 2 2 Glycosyl transferases group 1 Asp1 PF16993.5 OQR81573.1 - 0.0036 16.6 0.7 2.8 7.1 0.0 3.0 3 0 0 3 3 3 2 Accessory Sec system protein Asp1 Aminoglyc_resit PF10706.9 OQR81573.1 - 0.075 12.8 0.0 2.4 7.9 0.0 2.3 2 0 0 2 2 2 0 Aminoglycoside-2''-adenylyltransferase Lipase_bact_N PF12262.8 OQR81573.1 - 0.13 11.6 0.3 26 4.0 0.0 3.0 2 1 0 2 2 2 0 Bacterial virulence factor lipase N-terminal RNase_P_Rpp14 PF01900.19 OQR81574.1 - 1.5e-23 82.9 0.7 1.9e-23 82.6 0.7 1.1 1 0 0 1 1 1 1 Rpp14/Pop5 family SAP18 PF06487.12 OQR81575.1 - 1.4e-28 99.8 0.0 2.8e-28 98.8 0.0 1.5 1 1 0 1 1 1 1 Sin3 associated polypeptide p18 (SAP18) LSM PF01423.22 OQR81576.1 - 7.8e-22 76.7 0.0 8.7e-22 76.6 0.0 1.0 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 OQR81576.1 - 0.07 13.3 0.0 0.086 13.0 0.0 1.1 1 0 0 1 1 1 0 Ataxin 2 SM domain Pkinase PF00069.25 OQR81578.1 - 1.2e-57 195.2 0.0 1.6e-57 194.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQR81578.1 - 2.5e-24 86.0 0.0 3.4e-24 85.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase EF-hand_7 PF13499.6 OQR81578.1 - 3.5e-16 59.4 2.1 5.8e-07 29.9 0.0 3.3 3 1 0 3 3 2 2 EF-hand domain pair EF-hand_6 PF13405.6 OQR81578.1 - 3.1e-14 51.6 2.6 0.0039 17.0 0.2 4.7 4 0 0 4 4 4 3 EF-hand domain EF-hand_1 PF00036.32 OQR81578.1 - 7.2e-14 50.2 5.7 6.9e-05 22.1 0.2 3.7 3 0 0 3 3 3 3 EF hand EF-hand_5 PF13202.6 OQR81578.1 - 2.8e-12 45.5 3.1 0.0081 15.6 0.1 3.5 3 0 0 3 3 3 3 EF hand EF-hand_8 PF13833.6 OQR81578.1 - 1.3e-08 34.6 2.7 0.00027 20.7 0.2 3.5 3 0 0 3 3 3 3 EF-hand domain pair Kinase-like PF14531.6 OQR81578.1 - 0.00015 21.2 0.1 0.058 12.7 0.0 2.7 2 1 0 2 2 2 2 Kinase-like EF-hand_4 PF12763.7 OQR81578.1 - 0.00018 21.4 1.3 0.11 12.5 0.1 2.5 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 OQR81578.1 - 0.00077 19.8 1.0 0.1 12.9 0.2 2.5 2 0 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region APH PF01636.23 OQR81578.1 - 0.0042 17.0 0.6 3.3 7.6 0.1 2.4 2 0 0 2 2 2 2 Phosphotransferase enzyme family RIO1 PF01163.22 OQR81578.1 - 0.15 11.7 3.2 0.2 11.2 0.3 2.5 2 1 1 3 3 3 0 RIO1 family Iso_dh PF00180.20 OQR81579.1 - 8e-75 252.1 0.0 1.2e-74 251.6 0.0 1.2 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase HEAT_2 PF13646.6 OQR81579.1 - 0.14 12.5 0.3 5 7.6 0.1 3.4 2 1 1 3 3 3 0 HEAT repeats GIY-YIG PF01541.24 OQR81580.1 - 2.2e-12 47.1 0.0 4.8e-12 46.0 0.0 1.6 1 0 0 1 1 1 1 GIY-YIG catalytic domain zf-RING_2 PF13639.6 OQR81580.1 - 0.01 16.2 8.7 0.019 15.3 8.7 1.5 1 0 0 1 1 1 1 Ring finger domain C1_2 PF03107.16 OQR81580.1 - 0.028 14.7 1.5 0.028 14.7 1.5 2.0 2 0 0 2 2 2 0 C1 domain zf-HC5HC2H_2 PF13832.6 OQR81580.1 - 0.036 14.2 3.1 0.069 13.3 3.1 1.5 1 0 0 1 1 1 0 PHD-zinc-finger like domain FANCL_C PF11793.8 OQR81580.1 - 0.051 13.8 9.0 0.16 12.1 9.0 1.8 1 1 0 1 1 1 0 FANCL C-terminal domain zf-HC5HC2H PF13771.6 OQR81580.1 - 0.11 12.7 5.8 0.25 11.6 5.8 1.6 1 1 0 1 1 1 0 PHD-like zinc-binding domain zf-C3HC4 PF00097.25 OQR81580.1 - 0.12 12.3 7.2 0.29 11.0 7.2 1.7 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 OQR81580.1 - 0.67 9.9 5.1 1.7 8.6 2.2 2.3 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 zf-rbx1 PF12678.7 OQR81580.1 - 1.1 9.6 6.4 3.5 8.0 6.4 1.9 1 1 0 1 1 1 0 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 OQR81580.1 - 1.3 9.0 9.1 16 5.4 9.2 2.4 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING-like PF08746.11 OQR81580.1 - 2.8 8.3 7.0 6.7 7.1 7.0 1.7 1 0 0 1 1 1 0 RING-like domain CCT PF06203.14 OQR81581.1 - 1.1e-13 50.9 11.3 2.8e-13 49.7 11.3 1.7 1 0 0 1 1 1 1 CCT motif PDZ PF00595.24 OQR81581.1 - 0.0008 19.7 0.0 0.0018 18.6 0.0 1.6 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 OQR81581.1 - 0.00096 19.0 0.0 0.0026 17.5 0.0 1.8 1 0 0 1 1 1 1 PDZ domain UBA PF00627.31 OQR81581.1 - 0.018 15.0 0.0 0.038 13.9 0.0 1.5 1 0 0 1 1 1 0 UBA/TS-N domain SMK-1 PF04802.15 OQR81583.1 - 4.4e-35 121.3 1.6 2.2e-34 119.0 1.1 2.1 2 0 0 2 2 2 1 Component of IIS longevity pathway SMK-1 RIH_assoc PF08454.11 OQR81583.1 - 0.015 15.2 0.4 0.1 12.4 0.0 2.5 3 0 0 3 3 3 0 RyR and IP3R Homology associated Rib_5-P_isom_A PF06026.14 OQR81584.1 - 2.6e-62 209.5 0.0 3.9e-62 208.9 0.0 1.3 1 0 0 1 1 1 1 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) Arm PF00514.23 OQR81584.1 - 0.0038 17.2 7.8 5.4 7.2 0.2 5.5 4 1 1 5 5 5 2 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 OQR81584.1 - 0.022 15.2 7.0 0.33 11.4 2.9 3.5 2 2 1 3 3 3 0 HEAT repeats ABC_sub_bind PF04392.12 OQR81584.1 - 0.034 13.4 0.0 0.13 11.5 0.0 1.8 2 0 0 2 2 2 0 ABC transporter substrate binding protein DeoRC PF00455.22 OQR81584.1 - 0.039 13.9 0.1 0.46 10.4 0.0 2.4 1 1 0 2 2 2 0 DeoR C terminal sensor domain Cnd1 PF12717.7 OQR81584.1 - 0.13 12.3 6.2 0.23 11.5 0.1 3.0 2 2 1 3 3 3 0 non-SMC mitotic condensation complex subunit 1 PHD PF00628.29 OQR81585.1 - 0.00085 19.2 7.0 0.002 18.0 7.0 1.6 1 0 0 1 1 1 1 PHD-finger Tfb5 PF06331.12 OQR81585.1 - 0.015 15.2 1.7 0.034 14.1 0.4 2.3 2 0 0 2 2 2 0 Transcription factor TFIIH complex subunit Tfb5 DUF4734 PF15881.5 OQR81585.1 - 0.097 12.8 2.3 0.13 12.4 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4734) Phasin_2 PF09361.10 OQR81585.1 - 0.32 11.3 9.0 8.1 6.8 3.5 3.1 3 0 0 3 3 3 0 Phasin protein NAPRTase_C PF17956.1 OQR81585.1 - 1.7 9.1 7.5 2.3 8.7 0.4 3.2 2 1 0 2 2 2 0 Nicotinate phosphoribosyltransferase C-terminal domain zf-rbx1 PF12678.7 OQR81585.1 - 2.3 8.5 7.1 0.96 9.8 4.0 1.9 2 0 0 2 2 2 0 RING-H2 zinc finger domain Collectrin PF16959.5 OQR81585.1 - 2.7 7.7 6.1 9 6.1 0.8 3.3 1 1 2 3 3 3 0 Renal amino acid transporter Cupin_4 PF08007.12 OQR81586.1 - 2.2e-49 168.6 0.8 3.1e-49 168.2 0.8 1.2 1 0 0 1 1 1 1 Cupin superfamily protein Cupin_8 PF13621.6 OQR81586.1 - 4.4e-06 26.6 1.4 0.0092 15.7 0.0 2.7 2 1 0 2 2 2 2 Cupin-like domain Cupin_2 PF07883.11 OQR81586.1 - 0.012 15.3 0.1 0.042 13.6 0.0 1.8 2 0 0 2 2 2 0 Cupin domain Cupin_1 PF00190.22 OQR81586.1 - 0.04 13.5 0.0 0.067 12.8 0.0 1.4 1 0 0 1 1 1 0 Cupin CENP-B_dimeris PF09026.10 OQR81586.1 - 0.09 13.2 5.7 0.19 12.2 5.7 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain TFB6 PF17110.5 OQR81586.1 - 0.095 12.4 0.8 0.22 11.2 0.2 1.9 2 0 0 2 2 2 0 Subunit 11 of the general transcription factor TFIIH CPSF100_C PF13299.6 OQR81586.1 - 0.15 12.3 1.6 0.47 10.6 0.0 2.2 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal DNA_pol_phi PF04931.13 OQR81586.1 - 0.83 7.7 9.3 0.077 11.1 4.1 1.8 2 0 0 2 2 2 0 DNA polymerase phi NOA36 PF06524.12 OQR81586.1 - 3.7 6.8 10.2 6.7 5.9 10.2 1.4 1 0 0 1 1 1 0 NOA36 protein PP2C PF00481.21 OQR81587.1 - 1.2e-20 74.3 0.1 3e-19 69.7 0.1 2.8 1 1 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 OQR81587.1 - 3.7e-05 23.5 0.1 0.0003 20.5 0.1 2.1 1 1 0 1 1 1 1 Protein phosphatase 2C Sugar_tr PF00083.24 OQR81588.1 - 3.2e-108 362.5 27.5 3.6e-108 362.3 27.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OQR81588.1 - 1.3e-25 90.1 35.8 1.9e-19 69.8 12.4 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Metallophos PF00149.28 OQR81589.1 - 5.7e-13 49.8 0.2 7.9e-13 49.4 0.2 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 OQR81589.1 - 4.7e-05 23.6 0.0 0.00037 20.7 0.0 2.1 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Crystall PF00030.19 OQR81590.1 - 1.6e-07 31.4 0.1 4.3e-07 30.0 0.1 1.8 1 0 0 1 1 1 1 Beta/Gamma crystallin Metallophos PF00149.28 OQR81591.1 - 1.5e-26 94.1 0.1 7.3e-12 46.2 0.0 2.5 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase Peptidase_U57 PF05582.12 OQR81591.1 - 4.6e-05 22.8 0.0 0.15 11.3 0.0 2.3 2 0 0 2 2 2 2 YabG peptidase U57 Epimerase_2 PF02350.19 OQR81591.1 - 0.009 14.9 0.0 2.3 7.0 0.0 2.2 2 0 0 2 2 2 2 UDP-N-acetylglucosamine 2-epimerase MGDG_synth PF06925.11 OQR81591.1 - 0.024 14.8 0.3 4.1 7.5 0.0 2.8 3 0 0 3 3 3 0 Monogalactosyldiacylglycerol (MGDG) synthase PrsW-protease PF13367.6 OQR81591.1 - 0.052 13.0 0.4 6.5 6.1 0.0 2.2 2 0 0 2 2 2 0 PrsW family intramembrane metalloprotease End_N_terminal PF12218.8 OQR81591.1 - 0.13 12.0 0.0 4.8 7.0 0.0 2.5 2 0 0 2 2 2 0 N terminal extension of bacteriophage endosialidase SDF PF00375.18 OQR81592.1 - 7.1e-70 236.0 43.2 1.7e-68 231.5 43.2 2.0 1 1 0 1 1 1 1 Sodium:dicarboxylate symporter family DUF4704 PF15787.5 OQR81593.1 - 0.0026 17.0 0.1 0.11 11.7 0.0 2.7 2 1 0 2 2 2 1 Domain of unknown function (DUF4704) HEAT PF02985.22 OQR81593.1 - 0.0028 17.8 5.3 0.6 10.5 0.2 3.4 4 0 0 4 4 4 2 HEAT repeat Arm PF00514.23 OQR81593.1 - 0.0037 17.3 0.3 3.4 7.8 0.0 3.8 4 0 0 4 4 4 1 Armadillo/beta-catenin-like repeat SIL1 PF16782.5 OQR81593.1 - 0.0042 16.4 0.0 0.0074 15.5 0.0 1.5 1 0 0 1 1 1 1 Nucleotide exchange factor SIL1 Fes1 PF08609.10 OQR81593.1 - 0.0045 17.8 2.6 0.013 16.3 0.8 2.7 3 1 0 3 3 3 1 Nucleotide exchange factor Fes1 HEAT_2 PF13646.6 OQR81593.1 - 0.026 14.9 0.4 0.32 11.4 0.0 2.5 2 1 0 2 2 2 0 HEAT repeats U3snoRNP10 PF12397.8 OQR81593.1 - 0.065 13.6 0.2 2.5 8.5 0.2 2.8 2 1 0 2 2 2 0 U3 small nucleolar RNA-associated protein 10 rpo132 PF12415.8 OQR81593.1 - 0.086 12.1 0.1 0.16 11.3 0.1 1.4 1 0 0 1 1 1 0 Poxvirus DNA dependent RNA polymerase Glycos_transf_1 PF00534.20 OQR81594.1 - 7.2e-17 61.4 0.0 2.1e-16 60.0 0.0 1.8 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 OQR81594.1 - 9.5e-15 55.2 0.0 2.8e-14 53.7 0.0 1.8 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 OQR81594.1 - 0.0011 19.3 0.0 0.0021 18.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 SAICAR_synt PF01259.18 OQR81595.1 - 7.7e-77 258.3 0.0 9.4e-77 258.0 0.0 1.1 1 0 0 1 1 1 1 SAICAR synthetase Mg_trans_NIPA PF05653.14 OQR81596.1 - 3e-42 144.7 20.0 1.6e-41 142.3 20.0 1.9 1 1 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.20 OQR81596.1 - 8.6e-07 29.2 2.7 8.6e-07 29.2 2.7 3.0 2 1 1 3 3 3 1 EamA-like transporter family TMEM234 PF10639.9 OQR81596.1 - 0.02 14.9 0.6 0.047 13.7 0.1 2.0 2 0 0 2 2 2 0 Putative transmembrane family 234 Mito_carr PF00153.27 OQR81597.1 - 2e-124 405.9 6.0 1.2e-21 76.4 0.0 6.0 5 1 1 6 6 6 6 Mitochondrial carrier protein DUF2268 PF10026.9 OQR81597.1 - 0.06 12.9 0.0 3.1 7.3 0.0 2.3 2 0 0 2 2 2 0 Predicted Zn-dependent protease (DUF2268) MAPEG PF01124.18 OQR81599.1 - 1.1e-18 67.4 2.7 1.2e-18 67.2 2.7 1.0 1 0 0 1 1 1 1 MAPEG family V-ATPase_C PF03223.15 OQR81600.1 - 4.6e-109 365.2 0.2 1.1e-108 363.9 0.2 1.5 1 1 0 1 1 1 1 V-ATPase subunit C RecG_N PF17190.4 OQR81600.1 - 0.24 12.1 1.7 23 5.8 0.0 3.5 3 0 0 3 3 3 0 RecG N-terminal helical domain ATG11 PF10377.9 OQR81601.1 - 3.8e-21 75.5 0.0 1.5e-20 73.6 0.0 2.1 1 0 0 1 1 1 1 Autophagy-related protein 11 Abhydrolase_3 PF07859.13 OQR81601.1 - 2.8e-20 73.1 0.1 1.5e-19 70.7 0.1 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 OQR81601.1 - 1.6e-16 60.3 0.0 5.6e-16 58.5 0.0 1.9 1 1 0 1 1 1 1 Carboxylesterase family APG17 PF04108.12 OQR81601.1 - 9.4e-13 48.0 3.5 9.4e-13 48.0 3.5 3.7 2 2 0 2 2 1 1 Autophagy protein Apg17 Mlf1IP PF10248.9 OQR81601.1 - 0.002 18.2 2.0 0.002 18.1 0.1 2.1 2 0 0 2 2 1 1 Myelodysplasia-myeloid leukemia factor 1-interacting protein Abhydrolase_6 PF12697.7 OQR81601.1 - 0.007 17.0 0.2 0.018 15.6 0.2 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family LIDHydrolase PF10230.9 OQR81601.1 - 0.0098 15.5 0.3 0.28 10.7 0.1 2.7 2 0 0 2 2 2 1 Lipid-droplet associated hydrolase Peptidase_S9 PF00326.21 OQR81601.1 - 0.016 14.7 0.1 0.032 13.7 0.1 1.5 1 0 0 1 1 1 0 Prolyl oligopeptidase family KLRAQ PF10205.9 OQR81601.1 - 0.071 13.4 0.2 0.071 13.4 0.2 3.6 3 1 1 4 4 4 0 Predicted coiled-coil domain-containing protein Shugoshin_N PF07558.11 OQR81601.1 - 0.19 11.6 1.1 4.6 7.2 0.7 2.7 2 0 0 2 2 2 0 Shugoshin N-terminal coiled-coil region TSC22 PF01166.18 OQR81601.1 - 0.53 10.6 4.0 2.9 8.3 0.1 3.8 4 0 0 4 4 4 0 TSC-22/dip/bun family AKNA PF12443.8 OQR81601.1 - 1.3 9.7 5.4 31 5.3 0.2 3.4 3 0 0 3 3 3 0 AT-hook-containing transcription factor Fib_alpha PF08702.10 OQR81601.1 - 1.9 8.7 12.0 3.7 7.7 2.1 4.6 3 2 1 4 4 4 0 Fibrinogen alpha/beta chain family PHM7_cyt PF14703.6 OQR81601.1 - 2.9 8.1 6.5 16 5.7 0.0 3.8 4 0 0 4 4 4 0 Cytosolic domain of 10TM putative phosphate transporter P16-Arc PF04699.14 OQR81602.1 - 2.8e-30 105.8 0.0 3e-30 105.7 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex 16 kDa subunit (p16-Arc) DUF2937 PF11157.8 OQR81602.1 - 0.073 12.8 0.1 0.088 12.5 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2937) TFIIF_alpha PF05793.12 OQR81603.1 - 8e-23 80.8 41.0 1.6e-19 69.9 41.0 2.4 1 1 0 1 1 1 1 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Kelch_1 PF01344.25 OQR81604.1 - 1.3e-44 149.6 8.7 1.5e-09 37.2 0.0 6.3 6 0 0 6 6 6 6 Kelch motif Kelch_3 PF13415.6 OQR81604.1 - 8.1e-43 144.0 9.9 1.3e-10 41.2 0.2 5.5 5 0 0 5 5 5 5 Galactose oxidase, central domain Kelch_4 PF13418.6 OQR81604.1 - 1e-41 140.7 13.3 2.4e-09 37.1 0.1 6.3 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_5 PF13854.6 OQR81604.1 - 1.5e-40 136.5 5.5 2.3e-06 27.5 0.0 6.4 6 0 0 6 6 6 6 Kelch motif Kelch_2 PF07646.15 OQR81604.1 - 2.1e-38 128.9 8.5 1.8e-07 30.8 0.1 6.3 6 0 0 6 6 6 6 Kelch motif Kelch_6 PF13964.6 OQR81604.1 - 2.7e-38 129.0 10.8 8.3e-08 32.3 0.1 6.4 5 1 1 6 6 6 6 Kelch motif BTB PF00651.31 OQR81604.1 - 6.5e-24 84.3 3.4 6.8e-23 81.0 0.6 2.2 1 1 1 2 2 2 1 BTB/POZ domain BACK PF07707.15 OQR81604.1 - 0.00019 21.5 0.3 0.0033 17.5 0.0 2.4 2 0 0 2 2 2 1 BTB And C-terminal Kelch DUF1265 PF06887.14 OQR81604.1 - 0.27 11.3 1.6 0.64 10.0 1.6 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1265) Abhydrolase_1 PF00561.20 OQR81605.1 - 2.1e-24 86.5 0.1 3.3e-23 82.6 0.1 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 OQR81605.1 - 9.9e-21 75.4 0.0 1.2e-20 75.1 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 OQR81605.1 - 3.1e-18 65.9 0.0 4.2e-18 65.5 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 DLH PF01738.18 OQR81605.1 - 0.00012 21.8 0.2 0.04 13.5 0.0 2.5 2 1 0 2 2 2 2 Dienelactone hydrolase family BAAT_C PF08840.11 OQR81605.1 - 0.00018 21.5 0.0 0.00074 19.5 0.0 1.8 1 1 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal DUF1057 PF06342.12 OQR81605.1 - 0.00024 20.3 0.0 0.00036 19.7 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1057) Abhydrolase_3 PF07859.13 OQR81605.1 - 0.0021 17.9 0.0 0.0033 17.3 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_8 PF06259.12 OQR81605.1 - 0.0063 16.2 0.0 0.011 15.4 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase Palm_thioest PF02089.15 OQR81605.1 - 0.013 15.3 0.0 0.016 15.0 0.0 1.3 1 0 0 1 1 1 0 Palmitoyl protein thioesterase UPF0227 PF05728.12 OQR81605.1 - 0.016 15.1 0.9 0.09 12.7 0.1 2.5 2 2 1 3 3 3 0 Uncharacterised protein family (UPF0227) PGAP1 PF07819.13 OQR81605.1 - 0.017 14.8 0.0 0.026 14.3 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein Peptidase_C80 PF11713.8 OQR81605.1 - 0.021 15.1 0.0 0.047 13.9 0.0 1.5 1 0 0 1 1 1 0 Peptidase C80 family Lipase PF00151.19 OQR81605.1 - 0.054 12.8 0.0 0.089 12.1 0.0 1.4 1 1 0 1 1 1 0 Lipase Abhydrolase_2 PF02230.16 OQR81605.1 - 0.11 12.2 0.4 5.9 6.6 0.1 2.8 2 1 0 3 3 3 0 Phospholipase/Carboxylesterase Esterase PF00756.20 OQR81605.1 - 0.2 11.2 0.0 0.44 10.1 0.0 1.8 1 1 0 1 1 1 0 Putative esterase Sld5 PF05916.11 OQR81606.1 - 1.5e-10 41.5 0.0 2.3e-10 40.9 0.0 1.3 1 0 0 1 1 1 1 GINS complex protein Lon_C PF05362.13 OQR81607.1 - 3.9e-61 206.2 0.7 8.5e-61 205.1 0.7 1.5 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain LON_substr_bdg PF02190.16 OQR81607.1 - 1e-25 90.8 0.1 1.7e-25 90.2 0.1 1.3 1 0 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain WD40 PF00400.32 OQR81607.1 - 1.4e-24 85.9 18.0 6.4e-07 30.0 1.1 8.5 7 0 0 7 7 7 4 WD domain, G-beta repeat AAA PF00004.29 OQR81607.1 - 5e-22 78.7 0.0 1e-21 77.7 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ANAPC4_WD40 PF12894.7 OQR81607.1 - 1.4e-19 70.2 0.1 1.2e-07 31.9 0.0 6.1 2 1 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Ricin_B_lectin PF00652.22 OQR81607.1 - 2.4e-16 60.1 14.1 3.5e-10 40.2 3.0 4.1 2 1 3 5 5 5 4 Ricin-type beta-trefoil lectin domain Cellulase PF00150.18 OQR81607.1 - 3.9e-16 59.3 0.1 7.1e-16 58.5 0.1 1.4 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) AAA_5 PF07728.14 OQR81607.1 - 1.9e-11 44.1 0.0 4.8e-11 42.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) RicinB_lectin_2 PF14200.6 OQR81607.1 - 6.7e-09 36.4 9.3 5.2e-08 33.5 2.3 3.8 3 0 0 3 3 3 1 Ricin-type beta-trefoil lectin domain-like AAA_2 PF07724.14 OQR81607.1 - 9.2e-08 32.4 0.0 1.9e-07 31.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) Cytochrom_D1 PF02239.16 OQR81607.1 - 0.00024 19.8 0.1 0.044 12.3 0.0 2.6 1 1 2 3 3 3 2 Cytochrome D1 heme domain AAA_16 PF13191.6 OQR81607.1 - 0.00037 20.9 1.5 0.0069 16.8 0.1 3.2 2 2 1 3 3 3 1 AAA ATPase domain ChlI PF13541.6 OQR81607.1 - 0.00046 20.0 0.1 0.00092 19.1 0.1 1.5 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase AAA_PrkA PF08298.11 OQR81607.1 - 0.00046 19.2 0.0 0.00087 18.3 0.0 1.3 1 0 0 1 1 1 1 PrkA AAA domain AAA_22 PF13401.6 OQR81607.1 - 0.0011 19.2 1.3 0.056 13.7 0.8 2.8 2 1 0 2 2 1 1 AAA domain IstB_IS21 PF01695.17 OQR81607.1 - 0.0012 18.6 0.0 0.0036 17.1 0.0 1.7 1 0 0 1 1 1 1 IstB-like ATP binding protein Nup160 PF11715.8 OQR81607.1 - 0.0022 16.7 0.0 0.099 11.3 0.0 2.2 2 0 0 2 2 2 1 Nucleoporin Nup120/160 CDtoxinA PF03498.14 OQR81607.1 - 0.003 17.2 0.6 0.18 11.4 0.0 2.5 2 0 0 2 2 2 1 Cytolethal distending toxin A/C domain RuvB_N PF05496.12 OQR81607.1 - 0.0057 16.4 0.0 0.017 14.9 0.0 1.7 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain NACHT PF05729.12 OQR81607.1 - 0.0082 16.1 0.0 0.23 11.4 0.0 2.5 2 0 0 2 2 2 1 NACHT domain AAA_25 PF13481.6 OQR81607.1 - 0.012 15.1 0.3 0.14 11.7 0.0 2.8 3 0 0 3 3 2 0 AAA domain RsgA_GTPase PF03193.16 OQR81607.1 - 0.013 15.5 0.1 0.039 13.8 0.0 1.8 2 0 0 2 2 1 0 RsgA GTPase Ge1_WD40 PF16529.5 OQR81607.1 - 0.014 14.3 3.7 6.4 5.6 0.3 3.7 2 1 2 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 OQR81607.1 - 0.016 14.5 0.0 6.1 6.1 0.1 2.5 2 0 0 2 2 2 0 WD40-like domain AAA_3 PF07726.11 OQR81607.1 - 0.018 14.9 0.0 0.041 13.7 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 OQR81607.1 - 0.022 14.5 0.0 0.043 13.5 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain NB-ARC PF00931.22 OQR81607.1 - 0.045 12.9 0.0 0.23 10.6 0.0 2.1 2 0 0 2 2 2 0 NB-ARC domain Coatomer_WDAD PF04053.14 OQR81607.1 - 0.061 12.4 0.0 0.13 11.3 0.0 1.5 1 0 0 1 1 1 0 Coatomer WD associated region AAA_18 PF13238.6 OQR81607.1 - 0.077 13.5 0.0 0.19 12.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 OQR81607.1 - 0.082 12.9 0.0 0.21 11.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 OQR81607.1 - 0.089 13.2 0.0 0.29 11.5 0.0 2.0 1 0 0 1 1 1 0 RNA helicase NTPase_1 PF03266.15 OQR81607.1 - 0.096 12.6 0.1 17 5.3 0.0 2.4 1 1 1 2 2 2 0 NTPase AAA_24 PF13479.6 OQR81607.1 - 0.099 12.4 0.0 0.19 11.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain Roc PF08477.13 OQR81607.1 - 0.1 12.8 0.1 0.69 10.1 0.0 2.5 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_33 PF13671.6 OQR81607.1 - 0.13 12.5 0.0 0.27 11.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain Torsin PF06309.11 OQR81607.1 - 0.16 12.0 0.0 0.48 10.5 0.0 1.7 1 0 0 1 1 1 0 Torsin Mito_carr PF00153.27 OQR81608.1 - 9.2e-58 192.2 1.4 3.7e-19 68.4 0.0 4.0 4 0 0 4 4 4 4 Mitochondrial carrier protein Transketolase_N PF00456.21 OQR81609.1 - 1.4e-93 313.5 0.1 2.3e-93 312.8 0.1 1.3 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.24 OQR81609.1 - 5e-37 127.3 0.0 9.3e-37 126.4 0.0 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 OQR81609.1 - 1.9e-08 34.2 0.0 4.7e-08 33.0 0.0 1.6 1 0 0 1 1 1 1 Transketolase, C-terminal domain DXP_synthase_N PF13292.6 OQR81609.1 - 0.005 16.1 0.0 0.0072 15.6 0.0 1.3 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase E1_dh PF00676.20 OQR81609.1 - 0.037 13.0 0.0 0.054 12.4 0.0 1.2 1 0 0 1 1 1 0 Dehydrogenase E1 component CYYR1 PF10873.8 OQR81609.1 - 0.13 12.7 0.4 0.25 11.8 0.4 1.4 1 0 0 1 1 1 0 Cysteine and tyrosine-rich protein 1 Rho_GDI PF02115.17 OQR81610.1 - 5.5e-46 156.8 0.1 6e-46 156.7 0.1 1.0 1 0 0 1 1 1 1 RHO protein GDP dissociation inhibitor Kinesin PF00225.23 OQR81611.1 - 5e-80 268.9 0.0 9.2e-80 268.1 0.0 1.4 1 1 0 1 1 1 1 Kinesin motor domain DUF1681 PF07933.14 OQR81611.1 - 1.8e-38 131.5 0.0 3.8e-38 130.5 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1681) Microtub_bd PF16796.5 OQR81611.1 - 1.6e-20 73.6 0.0 3.1e-20 72.6 0.0 1.5 1 0 0 1 1 1 1 Microtubule binding AAA_16 PF13191.6 OQR81611.1 - 0.013 15.9 0.0 0.03 14.7 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain AAA_30 PF13604.6 OQR81611.1 - 0.066 12.9 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain STAR_dimer PF16544.5 OQR81611.1 - 0.083 12.5 0.3 0.19 11.3 0.3 1.6 1 0 0 1 1 1 0 Homodimerisation region of STAR domain protein ResIII PF04851.15 OQR81611.1 - 0.12 12.3 0.1 0.28 11.2 0.1 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit LOR PF04525.12 OQR81612.1 - 8.6e-08 32.0 0.0 1.1e-07 31.6 0.0 1.2 1 0 0 1 1 1 1 LURP-one-related OATP PF03137.20 OQR81613.1 - 1.5e-78 264.5 60.7 8.9e-19 67.2 2.5 10.1 3 3 5 8 8 8 6 Organic Anion Transporter Polypeptide (OATP) family MFS_1 PF07690.16 OQR81613.1 - 2.4e-75 253.6 114.5 9.6e-30 103.7 31.8 3.4 4 0 0 4 4 4 3 Major Facilitator Superfamily Sugar_tr PF00083.24 OQR81613.1 - 4.3e-22 78.6 87.0 3.5e-09 36.0 27.0 5.9 2 2 1 3 3 3 3 Sugar (and other) transporter zf-CCHC_5 PF14787.6 OQR81613.1 - 0.21 11.3 0.1 0.21 11.3 0.1 2.3 3 0 0 3 3 3 0 GAG-polyprotein viral zinc-finger TMEM51 PF15345.6 OQR81613.1 - 1.5 8.6 2.8 0.67 9.8 0.1 1.7 2 0 0 2 2 2 0 Transmembrane protein 51 DUF2614 PF11023.8 OQR81613.1 - 2.8 8.1 48.3 0.055 13.6 5.2 5.2 5 0 0 5 5 5 0 Zinc-ribbon containing domain LOR PF04525.12 OQR81614.1 - 9.3e-07 28.6 0.1 1.3e-06 28.2 0.1 1.1 1 0 0 1 1 1 1 LURP-one-related FeS_assembly_P PF01883.19 OQR81616.1 - 2.4e-13 50.1 0.0 4.9e-13 49.0 0.0 1.5 1 0 0 1 1 1 1 Iron-sulfur cluster assembly protein F-box-like PF12937.7 OQR81616.1 - 1.1e-05 25.2 0.1 2.8e-05 23.9 0.1 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 OQR81616.1 - 0.00072 19.4 0.2 0.0021 17.9 0.0 1.9 2 0 0 2 2 2 1 F-box domain MFS_1 PF07690.16 OQR81617.1 - 1.8e-48 165.3 79.3 9.5e-31 107.0 38.3 4.5 5 0 0 5 5 5 3 Major Facilitator Superfamily OATP PF03137.20 OQR81617.1 - 1e-40 139.6 37.1 4.2e-17 61.6 3.2 6.6 4 2 1 5 5 5 4 Organic Anion Transporter Polypeptide (OATP) family Sugar_tr PF00083.24 OQR81617.1 - 1.9e-24 86.4 42.2 1.4e-12 47.2 22.4 2.6 2 0 0 2 2 2 2 Sugar (and other) transporter DUF2157 PF09925.9 OQR81617.1 - 0.54 10.0 29.6 0.44 10.3 6.7 4.7 4 2 0 4 4 4 0 Predicted membrane protein (DUF2157) Bystin PF05291.11 OQR81618.1 - 3e-127 423.9 0.1 3.9e-127 423.5 0.1 1.1 1 0 0 1 1 1 1 Bystin Cyclin PF08613.11 OQR81619.1 - 1.5e-33 116.4 0.1 2.7e-33 115.6 0.1 1.4 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 OQR81619.1 - 9.3e-11 41.6 0.4 2e-10 40.5 0.4 1.6 1 1 0 1 1 1 1 Cyclin, N-terminal domain Pkinase PF00069.25 OQR81620.1 - 5.4e-09 35.8 0.0 1.3e-08 34.6 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain HEAT PF02985.22 OQR81620.1 - 1.1e-08 34.6 0.0 0.012 15.8 0.0 4.5 4 0 0 4 4 4 2 HEAT repeat Pkinase_Tyr PF07714.17 OQR81620.1 - 3.6e-06 26.4 0.0 6.3e-06 25.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase HEAT_2 PF13646.6 OQR81620.1 - 2.1e-05 24.8 0.0 0.0048 17.2 0.0 3.0 2 1 1 3 3 3 1 HEAT repeats Cnd1 PF12717.7 OQR81620.1 - 0.00083 19.4 0.2 0.0075 16.3 0.2 2.3 1 1 0 1 1 1 1 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 OQR81620.1 - 0.029 14.9 2.1 1.8 9.2 0.0 3.5 4 0 0 4 4 4 0 HEAT-like repeat Ehbp PF10622.9 OQR81620.1 - 0.17 12.0 0.0 0.42 10.7 0.0 1.6 1 0 0 1 1 1 0 Energy-converting hydrogenase B subunit P (EhbP) Rtt106 PF08512.12 OQR81621.1 - 1.1e-16 61.1 0.0 2.8e-16 59.7 0.0 1.7 1 0 0 1 1 1 1 Histone chaperone Rttp106-like ATP-synt_F PF01990.17 OQR81622.1 - 7.1e-32 109.6 0.3 8.1e-32 109.4 0.3 1.0 1 0 0 1 1 1 1 ATP synthase (F/14-kDa) subunit Arf PF00025.21 OQR81623.1 - 3.2e-79 264.4 0.0 3.7e-79 264.2 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 OQR81623.1 - 1.2e-14 54.6 0.0 1.6e-14 54.2 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 OQR81623.1 - 9e-13 48.1 0.0 9.8e-13 48.0 0.0 1.1 1 0 0 1 1 1 1 Ras family SRPRB PF09439.10 OQR81623.1 - 9.3e-13 48.0 0.0 1.2e-12 47.7 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 OQR81623.1 - 4.2e-12 45.9 0.5 4.9e-08 32.5 0.1 2.1 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.12 OQR81623.1 - 5.4e-09 35.8 0.0 6.9e-09 35.4 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 OQR81623.1 - 1.9e-05 24.7 0.0 2.9e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.18 OQR81623.1 - 0.0094 15.3 0.1 0.016 14.5 0.1 1.3 1 1 0 1 1 1 1 6-phosphofructo-2-kinase Pkinase PF00069.25 OQR81624.1 - 4.3e-69 232.8 0.0 5.1e-69 232.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQR81624.1 - 1.1e-30 106.8 0.0 1.4e-30 106.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OQR81624.1 - 5.8e-07 29.1 0.0 1.3e-06 27.9 0.0 1.6 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 OQR81624.1 - 0.0005 19.5 0.1 0.00085 18.7 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 OQR81624.1 - 0.0091 15.6 0.4 0.018 14.6 0.3 1.5 1 1 0 1 1 1 1 RIO1 family Pox_ser-thr_kin PF05445.11 OQR81624.1 - 0.028 13.4 0.0 0.045 12.7 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase APH PF01636.23 OQR81624.1 - 0.081 12.8 0.1 2.2 8.1 0.1 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family DUF2205 PF10224.9 OQR81625.1 - 2.5 8.1 9.4 11 6.1 1.4 3.7 2 1 1 3 3 3 0 Short coiled-coil protein Mtd_N PF18454.1 OQR81626.1 - 9.2 6.4 7.3 26 4.9 0.3 3.7 3 0 0 3 3 3 0 Major tropism determinant N-terminal domain Elicitin PF00964.17 OQR81627.1 - 1.1e-15 57.5 3.1 2e-15 56.6 3.1 1.5 1 0 0 1 1 1 1 Elicitin Methyltransf_31 PF13847.6 OQR81628.1 - 2.2e-13 50.3 0.0 3.7e-11 43.0 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OQR81628.1 - 9.2e-13 48.7 0.0 1.7e-11 44.6 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OQR81628.1 - 1.3e-12 48.2 0.0 1.7e-10 41.5 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OQR81628.1 - 4.4e-11 42.9 0.0 5.9e-11 42.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OQR81628.1 - 8.5e-11 42.5 0.0 2.1e-09 38.0 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain CheR PF01739.18 OQR81628.1 - 0.00077 19.0 0.0 0.0023 17.5 0.0 1.7 1 1 0 1 1 1 1 CheR methyltransferase, SAM binding domain TehB PF03848.14 OQR81628.1 - 0.038 13.4 0.0 0.055 12.9 0.0 1.2 1 0 0 1 1 1 0 Tellurite resistance protein TehB Ubie_methyltran PF01209.18 OQR81628.1 - 0.099 12.0 0.0 0.36 10.1 0.0 1.9 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family DREV PF05219.12 OQR81628.1 - 0.19 10.8 0.0 13 4.8 0.0 2.1 2 0 0 2 2 2 0 DREV methyltransferase T3SS_needle_F PF09392.10 OQR81629.1 - 0.029 14.5 1.7 0.066 13.4 1.7 1.5 1 0 0 1 1 1 0 Type III secretion needle MxiH, YscF, SsaG, EprI, PscF, EscF Thioredoxin_8 PF13905.6 OQR81630.1 - 1.7e-08 34.7 0.1 3.7e-08 33.6 0.1 1.6 1 1 0 1 1 1 1 Thioredoxin-like AhpC-TSA PF00578.21 OQR81630.1 - 2.9e-07 30.4 0.1 4.3e-07 29.9 0.1 1.2 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin PF00085.20 OQR81630.1 - 0.052 13.5 0.1 0.25 11.3 0.1 1.9 1 1 1 2 2 2 0 Thioredoxin DUF2847 PF11009.8 OQR81630.1 - 0.16 11.9 0.0 0.32 10.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2847) Pkinase PF00069.25 OQR81631.1 - 1.1e-45 156.1 0.0 2e-45 155.2 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQR81631.1 - 7.4e-17 61.5 0.0 1.2e-16 60.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.11 OQR81631.1 - 0.002 17.2 0.7 0.0064 15.5 0.0 1.9 2 0 0 2 2 2 1 Poxvirus serine/threonine protein kinase Kinase-like PF14531.6 OQR81631.1 - 0.013 14.8 0.9 0.27 10.5 0.1 2.2 1 1 1 2 2 2 0 Kinase-like DUF2183 PF09949.9 OQR81632.1 - 9.3e-07 29.1 0.0 2.1e-06 28.0 0.0 1.7 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2183) DFF-C PF09033.10 OQR81632.1 - 0.029 14.3 0.2 2.2 8.2 0.2 2.5 3 0 0 3 3 3 0 DNA Fragmentation factor 45kDa, C terminal domain SpoIIE PF07228.12 OQR81633.1 - 2.1e-10 40.8 0.0 3.2e-10 40.2 0.0 1.2 1 0 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.6 OQR81633.1 - 3.5e-06 26.8 0.0 6.9e-06 25.8 0.0 1.4 1 1 0 1 1 1 1 Protein phosphatase 2C PP2C PF00481.21 OQR81633.1 - 6.7e-06 25.9 0.1 0.066 12.8 0.0 2.2 2 0 0 2 2 2 2 Protein phosphatase 2C Exo_endo_phos PF03372.23 OQR81634.1 - 1.3e-07 31.4 0.0 2.7e-07 30.4 0.0 1.6 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family VBS PF08913.10 OQR81634.1 - 0.14 12.7 0.3 26 5.3 0.1 2.4 2 0 0 2 2 2 0 Vinculin Binding Site SNAP PF14938.6 OQR81635.1 - 2.6e-07 30.3 5.1 2.2e-06 27.3 5.1 2.0 1 1 0 1 1 1 1 Soluble NSF attachment protein, SNAP MIT PF04212.18 OQR81635.1 - 0.0092 16.0 1.6 0.06 13.4 1.7 2.3 2 0 0 2 2 2 1 MIT (microtubule interacting and transport) domain ANAPC4_WD40 PF12894.7 OQR81636.1 - 2.4e-06 27.7 0.6 0.67 10.3 0.0 3.5 2 1 1 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 OQR81636.1 - 0.006 17.4 2.8 1.7 9.6 0.1 3.7 4 0 0 4 4 4 2 WD domain, G-beta repeat RNA_pol_N PF01194.17 OQR81637.1 - 3.7e-31 107.2 1.0 4.2e-31 107.0 1.0 1.0 1 0 0 1 1 1 1 RNA polymerases N / 8 kDa subunit Chordopox_RPO7 PF05864.12 OQR81637.1 - 0.017 15.4 0.7 0.024 14.9 0.7 1.3 1 1 0 1 1 1 0 Chordopoxvirus DNA-directed RNA polymerase 7 kDa polypeptide (RPO7) cNMP_binding PF00027.29 OQR81639.1 - 1.3e-06 28.4 0.1 3.4e-06 27.0 0.0 1.7 1 1 0 1 1 1 1 Cyclic nucleotide-binding domain zf-CCHC_6 PF15288.6 OQR81639.1 - 0.0034 17.2 0.1 0.0066 16.3 0.1 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-C2HE PF16278.5 OQR81639.1 - 0.043 14.3 0.2 1.4 9.5 0.0 2.6 2 0 0 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger zf-CCHC PF00098.23 OQR81639.1 - 0.06 13.4 4.9 0.3 11.3 0.1 2.4 2 0 0 2 2 2 0 Zinc knuckle CpXC PF14353.6 OQR81639.1 - 0.089 12.8 1.1 0.58 10.2 0.1 2.2 2 0 0 2 2 2 0 CpXC protein Rad50_zn_hook PF04423.14 OQR81639.1 - 0.17 11.7 0.7 0.49 10.3 0.0 2.0 2 0 0 2 2 2 0 Rad50 zinc hook motif ORC3_N PF07034.11 OQR81640.1 - 3.7e-18 65.7 2.1 2.3e-17 63.1 2.1 2.2 1 1 0 1 1 1 1 Origin recognition complex (ORC) subunit 3 N-terminus ORC_WH_C PF18137.1 OQR81640.1 - 3.3e-13 49.9 0.4 1.3e-10 41.5 0.4 2.7 1 1 0 1 1 1 1 Origin recognition complex winged helix C-terminal THP2 PF09432.10 OQR81640.1 - 0.027 14.5 0.6 0.19 11.8 0.0 2.7 3 0 0 3 3 3 0 Tho complex subunit THP2 ParB_C PF18064.1 OQR81640.1 - 0.68 10.1 4.5 0.7 10.1 0.4 2.8 3 0 0 3 3 3 0 Centromere-binding protein ParB C-terminal Cytochrom_B561 PF03188.16 OQR81641.1 - 4.6e-17 62.4 4.0 4.6e-17 62.4 4.0 1.8 2 1 0 2 2 2 1 Eukaryotic cytochrome b561 Trp_oprn_chp PF09534.10 OQR81641.1 - 0.021 14.6 1.0 0.048 13.4 1.0 1.6 1 0 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) DUF3784 PF12650.7 OQR81641.1 - 0.052 13.7 10.7 1 9.6 0.5 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF3784) Cation_ATPase_C PF00689.21 OQR81641.1 - 0.29 10.8 9.4 0.41 10.3 2.7 2.8 1 1 1 2 2 2 0 Cation transporting ATPase, C-terminus CPBP PF02517.16 OQR81641.1 - 5.7 7.4 12.6 51 4.3 12.6 2.4 1 1 0 1 1 1 0 CPBP intramembrane metalloprotease zf-RING_2 PF13639.6 OQR81642.1 - 1.2e-09 38.4 12.4 2.5e-09 37.3 12.4 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 OQR81642.1 - 2.7e-08 33.5 12.8 5.2e-08 32.6 12.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 OQR81642.1 - 4.1e-06 27.0 14.6 1.8e-05 24.9 14.6 2.1 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 OQR81642.1 - 4.1e-05 23.4 12.7 8.7e-05 22.3 12.7 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 OQR81642.1 - 0.0004 20.1 10.1 0.00093 18.9 10.1 1.7 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_3 PF13920.6 OQR81642.1 - 0.00065 19.5 7.7 0.0013 18.6 7.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OQR81642.1 - 0.002 18.1 11.4 0.0044 16.9 11.4 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zinc_ribbon_16 PF17034.5 OQR81642.1 - 0.0025 18.0 0.8 0.0048 17.1 0.8 1.7 1 0 0 1 1 1 1 Zinc-ribbon like family zf-RING_UBOX PF13445.6 OQR81642.1 - 0.013 15.5 9.6 0.035 14.1 9.6 1.8 1 0 0 1 1 1 0 RING-type zinc-finger zf-ANAPC11 PF12861.7 OQR81642.1 - 0.015 15.3 7.7 0.051 13.6 7.7 1.9 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_10 PF16685.5 OQR81642.1 - 0.018 15.2 4.8 0.045 13.9 4.8 1.6 1 0 0 1 1 1 0 zinc RING finger of MSL2 Zn_ribbon_17 PF17120.5 OQR81642.1 - 0.042 13.5 8.6 0.077 12.6 8.6 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-C3HC4_4 PF15227.6 OQR81642.1 - 0.36 11.0 8.3 0.99 9.6 8.3 1.8 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 OQR81642.1 - 1.4 8.8 11.9 9.9 6.1 11.9 2.3 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 RINGv PF12906.7 OQR81642.1 - 1.8 8.8 7.7 6.1 7.1 7.7 1.9 1 1 0 1 1 1 0 RING-variant domain zf-P11 PF03854.14 OQR81642.1 - 5.9 6.6 9.5 38 4.1 9.7 2.1 1 1 1 2 2 2 0 P-11 zinc finger TIR_2 PF13676.6 OQR81643.1 - 1.9e-11 44.6 0.0 3.2e-11 43.9 0.0 1.4 1 0 0 1 1 1 1 TIR domain TIR PF01582.20 OQR81643.1 - 0.0016 18.3 0.0 0.0024 17.7 0.0 1.2 1 0 0 1 1 1 1 TIR domain Neurochondrin PF05536.11 OQR81644.1 - 2.8e-45 154.8 4.1 4e-44 151.0 4.0 2.0 1 1 0 1 1 1 1 Neurochondrin DUF389 PF04087.14 OQR81645.1 - 3e-13 50.0 0.9 7.1e-13 48.8 0.9 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF389) zf-RanBP PF00641.18 OQR81645.1 - 2.7 7.4 4.9 6 6.3 4.9 1.5 1 0 0 1 1 1 0 Zn-finger in Ran binding protein and others DZR PF12773.7 OQR81645.1 - 3.1 7.9 4.4 0.9 9.6 0.7 1.9 2 0 0 2 2 2 0 Double zinc ribbon LRR_9 PF14580.6 OQR81646.1 - 1.6e-07 31.0 1.0 1.6e-07 31.0 1.0 2.8 3 0 0 3 3 3 1 Leucine-rich repeat LRR_4 PF12799.7 OQR81646.1 - 5.5e-06 26.6 23.3 0.074 13.5 0.5 6.8 6 1 1 7 7 7 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 OQR81646.1 - 8.6e-05 22.2 24.8 0.006 16.3 0.6 5.1 3 1 2 5 5 5 3 Leucine rich repeat WW PF00397.26 OQR81646.1 - 0.00012 22.1 5.5 0.00023 21.2 5.5 1.5 1 0 0 1 1 1 1 WW domain LRR_6 PF13516.6 OQR81646.1 - 0.0015 18.4 22.8 0.24 11.6 0.1 7.6 8 0 0 8 8 8 2 Leucine Rich repeat DUF3349 PF11829.8 OQR81646.1 - 0.2 12.5 0.0 0.2 12.5 0.0 3.4 3 1 1 4 4 4 0 Protein of unknown function (DUF3349) LRR_1 PF00560.33 OQR81646.1 - 2.4 9.1 14.5 3.9 8.4 0.7 6.0 4 2 0 4 4 4 0 Leucine Rich Repeat Hydrolase_6 PF13344.6 OQR81647.1 - 5.5e-21 74.6 0.0 2.1e-20 72.7 0.0 2.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase MAD PF05557.13 OQR81647.1 - 2.2e-19 69.3 11.4 2.2e-19 69.3 11.4 2.9 1 1 1 2 2 2 1 Mitotic checkpoint protein Pox_A_type_inc PF04508.12 OQR81647.1 - 9e-05 22.2 2.4 0.0063 16.3 0.2 3.6 3 0 0 3 3 3 1 Viral A-type inclusion protein repeat DUF1664 PF07889.12 OQR81647.1 - 0.019 15.0 0.4 0.019 15.0 0.4 4.1 4 0 0 4 4 4 0 Protein of unknown function (DUF1664) SMBP PF16785.5 OQR81647.1 - 0.11 12.7 0.2 0.11 12.7 0.2 2.1 2 0 0 2 2 2 0 Small metal-binding protein DUF4259 PF14078.6 OQR81647.1 - 0.24 12.1 5.6 0.13 13.0 1.6 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4259) HALZ PF02183.18 OQR81647.1 - 0.78 10.0 7.2 3.7 7.9 0.4 3.0 2 0 0 2 2 2 0 Homeobox associated leucine zipper CENP-F_leu_zip PF10473.9 OQR81647.1 - 2.9 7.9 35.8 0.88 9.6 7.4 4.4 2 2 2 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ATG16 PF08614.11 OQR81647.1 - 7 6.8 40.9 1.9 8.6 12.8 4.3 1 1 1 3 3 3 0 Autophagy protein 16 (ATG16) 2-Hacid_dh_C PF02826.19 OQR81649.1 - 5.3e-42 143.2 0.0 8.3e-42 142.5 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_2 PF03446.15 OQR81649.1 - 0.00052 20.2 0.2 0.0017 18.5 0.0 1.9 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 OQR81649.1 - 0.046 14.3 0.0 0.11 13.1 0.0 1.7 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Sacchrp_dh_NADP PF03435.18 OQR81649.1 - 0.15 12.3 1.2 1 9.6 1.2 2.2 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain HMG-CoA_red PF00368.18 OQR81650.1 - 3.3e-91 306.1 4.9 5.8e-91 305.2 4.9 1.4 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A reductase ACPS PF01648.20 OQR81651.1 - 8.6e-15 54.9 0.1 1.4e-14 54.2 0.1 1.6 1 1 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily 4PPT_N PF17837.1 OQR81651.1 - 0.1 12.7 0.3 4 7.6 0.0 2.4 2 0 0 2 2 2 0 4'-phosphopantetheinyl transferase N-terminal domain Got1 PF04178.12 OQR81652.1 - 3.4e-27 95.1 16.1 1.2e-26 93.4 15.0 1.9 1 1 1 2 2 2 2 Got1/Sft2-like family DUF5337 PF17272.2 OQR81652.1 - 0.54 10.1 3.7 1.2 9.0 3.7 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5337) CWC25 PF12542.8 OQR81653.1 - 1.1e-17 64.8 2.6 1.1e-17 64.8 2.6 4.8 4 2 0 4 4 4 1 Pre-mRNA splicing factor Cir_N PF10197.9 OQR81653.1 - 2.8e-13 49.8 11.6 2.8e-13 49.8 11.6 6.5 6 1 0 6 6 6 1 N-terminal domain of CBF1 interacting co-repressor CIR TPT PF03151.16 OQR81656.1 - 6.8e-30 104.4 19.4 9.3e-30 104.0 19.4 1.2 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 OQR81656.1 - 2e-10 41.0 23.7 7.6e-08 32.6 4.6 2.2 2 0 0 2 2 2 2 EamA-like transporter family UAA PF08449.11 OQR81656.1 - 0.00012 21.5 12.9 0.00012 21.5 12.9 2.4 1 1 1 2 2 2 1 UAA transporter family Elicitin PF00964.17 OQR81657.1 - 0.014 15.5 5.7 0.014 15.5 5.7 2.1 1 1 1 2 2 2 0 Elicitin Pkinase PF00069.25 OQR81658.1 - 2.4e-67 227.1 0.0 3.4e-67 226.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQR81658.1 - 3.6e-35 121.5 0.0 5.3e-35 121.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase EF-hand_7 PF13499.6 OQR81658.1 - 1.2e-31 109.0 2.0 4e-16 59.2 0.2 2.6 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 OQR81658.1 - 1.3e-29 99.5 14.0 1.3e-07 30.6 0.5 4.7 4 0 0 4 4 4 4 EF hand EF-hand_5 PF13202.6 OQR81658.1 - 6.1e-24 82.4 7.6 9.7e-06 24.9 0.0 4.4 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.6 OQR81658.1 - 5.6e-23 78.9 9.5 3.1e-05 23.6 0.3 4.7 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 OQR81658.1 - 1.6e-22 79.1 9.6 2.9e-11 43.0 0.1 4.1 3 2 2 5 5 5 4 EF-hand domain pair EF-hand_4 PF12763.7 OQR81658.1 - 4.5e-10 39.4 0.5 0.00047 20.1 0.0 2.7 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.6 OQR81658.1 - 3.2e-06 27.4 0.1 0.087 13.2 0.0 2.9 2 0 0 2 2 2 2 EF-hand domain SPARC_Ca_bdg PF10591.9 OQR81658.1 - 3.4e-06 27.4 0.0 0.0087 16.4 0.0 2.5 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region Kdo PF06293.14 OQR81658.1 - 0.00023 20.6 0.2 0.0004 19.8 0.2 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Dockerin_1 PF00404.18 OQR81658.1 - 0.00025 21.2 2.5 0.061 13.5 0.5 3.0 2 1 0 2 2 2 1 Dockerin type I domain Pkinase_fungal PF17667.1 OQR81658.1 - 0.0052 15.6 0.0 0.0087 14.9 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase TerB PF05099.13 OQR81658.1 - 0.0082 16.1 0.0 0.93 9.4 0.0 2.4 2 0 0 2 2 2 1 Tellurite resistance protein TerB EF-hand_11 PF08976.11 OQR81658.1 - 0.0087 16.9 0.0 8.7 7.3 0.0 2.4 1 1 1 2 2 2 2 EF-hand domain APH PF01636.23 OQR81658.1 - 0.021 14.7 0.8 0.021 14.7 0.8 2.0 2 1 1 3 3 3 0 Phosphotransferase enzyme family ZZ PF00569.17 OQR81658.1 - 0.046 13.5 1.2 0.13 12.1 1.2 1.7 1 0 0 1 1 1 0 Zinc finger, ZZ type Rhomboid PF01694.22 OQR81659.1 - 3.6e-20 72.5 6.7 9.8e-13 48.4 0.5 2.3 2 0 0 2 2 2 2 Rhomboid family IBR PF01485.21 OQR81660.1 - 1e-20 73.7 45.5 1.7e-12 47.4 6.1 4.4 3 1 0 3 3 3 2 IBR domain, a half RING-finger domain zf-C3HC4_2 PF13923.6 OQR81660.1 - 0.00023 20.9 1.8 0.00023 20.9 1.8 4.5 4 1 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 OQR81660.1 - 0.0011 18.8 1.0 0.0011 18.8 1.0 4.0 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OQR81660.1 - 0.0012 18.8 1.9 0.0012 18.8 1.9 4.0 3 1 0 3 3 3 1 RING-type zinc-finger zf-RING_2 PF13639.6 OQR81660.1 - 0.0076 16.6 3.9 0.0076 16.6 3.9 4.2 2 1 1 3 3 3 1 Ring finger domain zf-dskA_traR PF01258.17 OQR81660.1 - 1.7 8.6 11.1 0.62 10.1 1.4 3.3 2 0 0 2 2 2 0 Prokaryotic dksA/traR C4-type zinc finger zf-C3HC4_4 PF15227.6 OQR81660.1 - 3.3 7.9 32.8 0.32 11.2 4.7 4.1 3 1 1 4 4 4 0 zinc finger of C3HC4-type, RING EF-hand_8 PF13833.6 OQR81662.1 - 0.024 14.5 0.5 0.93 9.4 0.0 3.4 3 0 0 3 3 3 0 EF-hand domain pair VP4_2 PF08935.10 OQR81662.1 - 0.091 13.4 0.1 33 5.2 0.0 3.1 3 0 0 3 3 3 0 Viral protein VP4 subunit FXR_C1 PF16096.5 OQR81662.1 - 0.091 13.0 3.9 0.2 11.9 3.9 1.5 1 0 0 1 1 1 0 Fragile X-related 1 protein C-terminal region 2 EF-hand_11 PF08976.11 OQR81662.1 - 0.13 13.2 0.0 2 9.3 0.0 2.5 2 0 0 2 2 2 0 EF-hand domain SLX9 PF15341.6 OQR81662.1 - 0.18 12.2 8.0 0.045 14.1 4.1 2.0 2 0 0 2 2 2 0 Ribosome biogenesis protein SLX9 EF-hand_7 PF13499.6 OQR81662.1 - 1.6 9.2 6.9 2.5 8.6 0.0 4.2 5 0 0 5 5 5 0 EF-hand domain pair DUF1664 PF07889.12 OQR81662.1 - 6.2 6.9 5.3 1.4 9.0 0.1 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) DAP3 PF10236.9 OQR81663.1 - 2.3e-25 89.4 0.0 3.1e-25 89.0 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal death-associated protein 3 AAA_16 PF13191.6 OQR81663.1 - 0.002 18.6 0.0 0.0035 17.8 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_30 PF13604.6 OQR81663.1 - 0.0092 15.7 0.0 0.021 14.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain DUF2431 PF10354.9 OQR81664.1 - 1.3e-31 110.2 0.0 2.6e-31 109.1 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF2431) zf-C2H2_4 PF13894.6 OQR81664.1 - 1.1e-13 50.8 13.2 0.027 15.3 1.0 5.0 4 0 0 4 4 4 4 C2H2-type zinc finger zf-C2H2 PF00096.26 OQR81664.1 - 5e-11 42.4 9.9 0.012 16.0 0.1 5.0 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 OQR81664.1 - 1.6e-08 34.6 7.8 0.019 15.2 0.1 4.5 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 OQR81664.1 - 5.2e-08 32.7 9.6 0.078 13.0 0.1 4.6 4 0 0 4 4 4 3 C2H2-type zinc finger MTS PF05175.14 OQR81664.1 - 0.00018 21.1 0.0 0.0003 20.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain zf-C2H2_11 PF16622.5 OQR81664.1 - 0.0018 18.0 4.3 0.56 10.0 0.0 4.5 4 0 0 4 4 4 1 zinc-finger C2H2-type Methyltransf_4 PF02390.17 OQR81664.1 - 0.0022 17.5 0.2 0.0037 16.8 0.2 1.4 1 0 0 1 1 1 1 Putative methyltransferase zf-C2H2_2 PF12756.7 OQR81664.1 - 0.0043 17.4 20.1 0.56 10.6 3.4 4.9 2 2 2 4 4 4 3 C2H2 type zinc-finger (2 copies) zf-H2C2_2 PF13465.6 OQR81664.1 - 0.021 15.3 3.3 9.6 6.8 0.1 4.0 3 1 0 3 3 3 0 Zinc-finger double domain zf-C2H2_8 PF15909.5 OQR81664.1 - 0.045 14.0 2.8 0.89 9.9 0.5 2.7 1 1 1 2 2 2 0 C2H2-type zinc ribbon zf-met PF12874.7 OQR81664.1 - 0.69 10.4 9.4 14 6.2 0.1 4.3 4 0 0 4 4 4 0 Zinc-finger of C2H2 type Zn_ribbon_SprT PF17283.2 OQR81664.1 - 1.5 8.8 7.5 4.4 7.3 0.2 3.0 3 0 0 3 3 3 0 SprT-like zinc ribbon domain zf-met2 PF12907.7 OQR81664.1 - 1.6 9.0 7.7 5.2 7.3 0.2 3.5 3 0 0 3 3 3 0 Zinc-binding BolA PF01722.18 OQR81664.1 - 2.1 8.7 6.5 24 5.3 2.0 3.7 4 1 1 5 5 5 0 BolA-like protein zf_UBZ PF18439.1 OQR81664.1 - 2.8 7.6 5.7 2.6 7.7 0.1 3.1 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger Tcp11 PF05794.13 OQR81665.1 - 4.3e-36 125.0 4.5 4.3e-36 125.0 4.5 2.8 2 1 0 3 3 3 1 T-complex protein 11 BTRD1 PF17660.1 OQR81665.1 - 0.081 12.8 2.9 13 5.7 0.2 3.5 3 0 0 3 3 3 0 Bacterial tandem repeat domain 1 MatE PF01554.18 OQR81666.1 - 6.7e-47 159.1 29.1 5.2e-26 91.2 10.7 2.3 2 0 0 2 2 2 2 MatE Polysacc_synt_C PF14667.6 OQR81666.1 - 9.3e-05 22.5 11.3 0.0037 17.3 5.5 3.8 3 2 1 4 4 4 2 Polysaccharide biosynthesis C-terminal domain Got1 PF04178.12 OQR81667.1 - 5e-30 104.2 10.0 8.1e-30 103.6 9.9 1.4 1 1 0 1 1 1 1 Got1/Sft2-like family FKBP_C PF00254.28 OQR81668.1 - 6.9e-31 106.4 0.0 1.8e-30 105.1 0.0 1.7 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase NPL PF17800.1 OQR81668.1 - 1.4e-13 51.3 0.0 1.4e-13 51.3 0.0 2.4 2 1 0 2 2 1 1 Nucleoplasmin-like domain YL1 PF05764.13 OQR81668.1 - 0.0021 18.2 18.3 0.003 17.7 18.3 1.2 1 0 0 1 1 1 1 YL1 nuclear protein Presenilin PF01080.17 OQR81668.1 - 0.075 11.8 10.3 0.098 11.4 10.3 1.1 1 0 0 1 1 1 0 Presenilin GAGA_bind PF06217.12 OQR81668.1 - 0.08 13.2 6.2 0.1 12.9 6.2 1.3 1 0 0 1 1 1 0 GAGA binding protein-like family CDC45 PF02724.14 OQR81668.1 - 0.6 8.3 17.9 0.77 8.0 17.9 1.1 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 OQR81668.1 - 0.61 8.2 21.0 0.74 8.0 21.0 1.1 1 0 0 1 1 1 0 Nop14-like family Lin-8 PF03353.15 OQR81668.1 - 0.63 9.5 13.6 0.84 9.1 13.6 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist DUF908 PF06012.12 OQR81668.1 - 1.4 8.2 5.4 1.8 7.9 5.4 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) Borrelia_P83 PF05262.11 OQR81668.1 - 1.5 7.3 17.8 1.9 6.9 17.8 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein SDA1 PF05285.12 OQR81668.1 - 2.7 7.3 29.2 3.8 6.9 29.2 1.1 1 0 0 1 1 1 0 SDA1 RR_TM4-6 PF06459.12 OQR81668.1 - 3.4 7.4 18.5 6 6.6 18.5 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 IGFL PF14653.6 OQR81669.1 - 0.056 13.4 2.0 0.14 12.1 1.6 1.8 2 0 0 2 2 2 0 Insulin growth factor-like family Dimer_Tnp_hAT PF05699.14 OQR81670.1 - 4.6e-09 35.9 0.1 9.5e-09 34.9 0.1 1.6 1 1 0 1 1 1 1 hAT family C-terminal dimerisation region Mannitol_dh_C PF08125.13 OQR81671.1 - 3.4e-09 36.6 0.1 5.3e-08 32.6 0.1 2.2 1 1 0 1 1 1 1 Mannitol dehydrogenase C-terminal domain Metallophos PF00149.28 OQR81672.1 - 4e-08 34.0 1.0 1.8e-07 31.9 0.1 2.4 2 1 0 2 2 2 1 Calcineurin-like phosphoesterase ATP-synt_E PF05680.12 OQR81673.1 - 0.086 13.2 0.2 0.15 12.4 0.2 1.3 1 0 0 1 1 1 0 ATP synthase E chain Ank_4 PF13637.6 OQR81674.1 - 1.7e-08 34.8 1.1 2.5e-05 24.7 0.1 2.4 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 OQR81674.1 - 2.1e-07 31.5 0.1 2.7e-07 31.1 0.1 1.2 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OQR81674.1 - 1.3e-06 28.5 0.1 0.011 16.1 0.0 2.4 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQR81674.1 - 2.7e-06 27.3 0.0 0.027 15.0 0.0 2.8 3 0 0 3 3 3 2 Ankyrin repeat Ank PF00023.30 OQR81674.1 - 0.061 13.8 0.0 2.7 8.6 0.0 2.5 2 1 0 2 2 2 0 Ankyrin repeat PhoD PF09423.10 OQR81675.1 - 1.9e-12 46.9 0.5 3e-12 46.2 0.5 1.2 1 0 0 1 1 1 1 PhoD-like phosphatase Ski_Sno PF02437.17 OQR81675.1 - 0.066 13.0 0.0 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 SKI/SNO/DAC family Tom22 PF04281.13 OQR81678.1 - 1.7e-06 27.8 0.2 2.3e-06 27.4 0.2 1.2 1 0 0 1 1 1 1 Mitochondrial import receptor subunit Tom22 DUF898 PF05987.13 OQR81678.1 - 0.051 12.6 0.0 0.051 12.6 0.0 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF898) DUF98 PF01947.16 OQR81679.1 - 3.4e-47 160.2 0.0 4e-47 159.9 0.0 1.1 1 0 0 1 1 1 1 p-hydroxybenzoic acid synthase DPM2 PF07297.12 OQR81680.1 - 2.7e-31 107.7 3.2 3e-31 107.5 3.2 1.0 1 0 0 1 1 1 1 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) PIG-P PF08510.12 OQR81680.1 - 1.3e-06 28.3 1.1 1.5e-06 28.1 1.1 1.1 1 0 0 1 1 1 1 PIG-P DUF3536 PF12055.8 OQR81681.1 - 0.14 11.5 0.0 0.17 11.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3536) Ribosomal_L34 PF00468.17 OQR81682.1 - 1.2e-13 50.8 11.2 2.1e-13 50.0 11.2 1.4 1 0 0 1 1 1 1 Ribosomal protein L34 BPL_LplA_LipB PF03099.19 OQR81682.1 - 0.17 11.8 0.0 0.31 10.9 0.0 1.4 1 0 0 1 1 1 0 Biotin/lipoate A/B protein ligase family BRCA-2_OB1 PF09103.10 OQR81683.1 - 4.5e-19 68.6 0.0 2.6e-18 66.1 0.0 2.3 1 1 0 1 1 1 1 BRCA2, oligonucleotide/oligosaccharide-binding, domain 1 BRCA2 PF00634.18 OQR81683.1 - 1.5e-16 59.8 16.3 0.0099 15.5 0.4 6.6 6 0 0 6 6 6 5 BRCA2 repeat BRCA-2_helical PF09169.10 OQR81683.1 - 7e-12 45.4 0.0 2.3e-11 43.7 0.0 1.9 1 0 0 1 1 1 1 BRCA2, helical RMI1_C PF16099.5 OQR81683.1 - 0.018 14.9 0.1 0.046 13.6 0.1 1.7 1 0 0 1 1 1 0 Recq-mediated genome instability protein 1, C-terminal OB-fold PBP3 PF18056.1 OQR81683.1 - 0.25 11.5 1.0 3 8.0 0.0 2.9 3 0 0 3 3 3 0 Penicillin Binding Protein 3 Domain DNA_pol_A_exo1 PF01612.20 OQR81684.1 - 4.6e-18 65.5 0.1 1.1e-17 64.3 0.1 1.6 1 0 0 1 1 1 1 3'-5' exonuclease PPR_2 PF13041.6 OQR81684.1 - 2.4e-15 56.5 0.0 9.8e-10 38.5 0.0 4.3 3 1 1 4 4 4 3 PPR repeat family PPR_3 PF13812.6 OQR81684.1 - 1.3e-09 37.9 0.1 1.9e-05 24.6 0.0 4.9 4 1 2 6 6 6 3 Pentatricopeptide repeat domain PPR PF01535.20 OQR81684.1 - 2.5e-08 33.6 0.3 0.0093 16.2 0.0 4.8 4 0 0 4 4 4 2 PPR repeat PPR_1 PF12854.7 OQR81684.1 - 4.6e-07 29.4 1.1 0.16 11.7 0.0 4.7 5 0 0 5 5 5 2 PPR repeat PPR_long PF17177.4 OQR81684.1 - 0.0023 17.4 0.3 0.014 14.8 0.2 2.2 2 0 0 2 2 2 1 Pentacotripeptide-repeat region of PRORP TPR_14 PF13428.6 OQR81684.1 - 0.1 13.5 0.1 16 6.6 0.0 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat Ssl1 PF04056.14 OQR81685.1 - 0.059 13.2 0.3 4.6 7.0 0.0 2.3 2 0 0 2 2 2 0 Ssl1-like JAB PF01398.21 OQR81687.1 - 2.8e-32 111.2 0.6 5.7e-32 110.2 0.0 1.8 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.6 OQR81687.1 - 7.6e-15 55.3 0.5 1.3e-14 54.6 0.5 1.4 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function Prok-JAB PF14464.6 OQR81687.1 - 4.9e-06 26.3 0.0 8.4e-06 25.6 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain DUF5624 PF18538.1 OQR81687.1 - 0.00093 19.3 0.1 0.0017 18.4 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF5624) Baculo_ME53 PF06061.11 OQR81687.1 - 0.021 14.1 0.2 0.031 13.5 0.2 1.2 1 0 0 1 1 1 0 Baculoviridae ME53 SUR7 PF06687.12 OQR81688.1 - 1.5e-05 24.7 5.0 4.2e-05 23.3 3.3 2.1 2 0 0 2 2 2 1 SUR7/PalI family Claudin_2 PF13903.6 OQR81688.1 - 0.0012 18.6 4.4 0.025 14.3 4.4 2.2 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction DUF2207 PF09972.9 OQR81688.1 - 0.0053 15.6 0.1 0.0079 15.0 0.1 1.2 1 0 0 1 1 1 1 Predicted membrane protein (DUF2207) Amastin PF07344.11 OQR81688.1 - 0.0063 16.4 2.9 0.041 13.7 0.3 2.4 2 0 0 2 2 2 1 Amastin surface glycoprotein DUF4293 PF14126.6 OQR81688.1 - 0.024 14.9 0.5 0.043 14.1 0.2 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4293) Clc-like PF07062.12 OQR81688.1 - 0.15 11.5 10.1 1.1 8.7 0.1 3.0 2 1 0 2 2 2 0 Clc-like YrhK PF14145.6 OQR81689.1 - 1.2e-22 79.5 23.8 6.3e-09 35.6 2.9 3.4 3 0 0 3 3 3 3 YrhK-like protein DUF423 PF04241.15 OQR81689.1 - 0.48 10.7 9.7 1 9.6 0.4 3.3 3 1 0 3 3 3 0 Protein of unknown function (DUF423) EamA PF00892.20 OQR81689.1 - 2.1 8.5 17.3 0.1 12.8 3.3 3.1 2 1 1 3 3 3 0 EamA-like transporter family VitD-bind_III PF09164.10 OQR81690.1 - 0.092 12.7 0.0 0.27 11.2 0.0 1.8 1 0 0 1 1 1 0 Vitamin D binding protein, domain III PX PF00787.24 OQR81691.1 - 6.5e-09 35.8 1.3 1.1e-07 31.8 0.3 3.1 2 0 0 2 2 2 1 PX domain PikAIV_N PF18605.1 OQR81691.1 - 2.6 7.7 12.4 0.31 10.6 5.7 3.3 2 0 0 2 2 2 0 Narbonolide/10-deoxymethynolide synthase PikA4 N-terminal domain Ricin_B_lectin PF00652.22 OQR81695.1 - 1.8e-19 70.2 14.7 1.2e-09 38.5 3.0 3.0 1 1 1 3 3 3 3 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.6 OQR81695.1 - 2.1e-07 31.6 5.1 0.0019 18.8 0.3 3.3 2 2 1 3 3 3 2 Ricin-type beta-trefoil lectin domain-like Mvb12 PF09452.10 OQR81695.1 - 0.02 15.3 0.0 0.045 14.2 0.0 1.6 1 0 0 1 1 1 0 ESCRT-I subunit Mvb12 5_nucleotid_C PF02872.18 OQR81696.1 - 7.7e-33 113.9 0.0 1.8e-16 60.7 0.0 2.9 3 0 0 3 3 3 2 5'-nucleotidase, C-terminal domain Metallophos PF00149.28 OQR81696.1 - 3.3e-09 37.5 0.0 7e-09 36.5 0.0 1.6 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase SAM_adeno_trans PF01887.16 OQR81696.1 - 0.015 14.7 0.3 5.2 6.4 0.0 2.6 3 0 0 3 3 3 0 S-adenosyl-l-methionine hydroxide adenosyltransferase VRR_NUC PF08774.11 OQR81697.1 - 1.9e-13 50.4 0.0 6e-13 48.8 0.0 1.9 1 1 0 1 1 1 1 VRR-NUC domain TPR_14 PF13428.6 OQR81697.1 - 0.034 15.0 2.0 23 6.2 0.0 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.6 OQR81697.1 - 0.038 14.6 0.4 0.71 10.6 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.28 OQR81697.1 - 0.067 13.0 0.8 4.5 7.3 0.1 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_15 PF13429.6 OQR81697.1 - 0.11 11.6 0.1 0.3 10.3 0.1 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat Pkinase PF00069.25 OQR81698.1 - 3.2e-66 223.4 0.3 1.3e-65 221.4 0.0 2.2 2 1 1 3 3 3 1 Protein kinase domain cNMP_binding PF00027.29 OQR81698.1 - 2.2e-58 194.3 0.2 1.6e-20 72.9 0.0 3.7 3 0 0 3 3 3 3 Cyclic nucleotide-binding domain Pkinase_Tyr PF07714.17 OQR81698.1 - 1.7e-31 109.5 0.3 8.4e-31 107.2 0.0 2.4 3 0 0 3 3 3 1 Protein tyrosine kinase VASt PF16016.5 OQR81698.1 - 6.1e-26 91.7 0.5 2.3e-25 89.8 0.5 2.1 1 0 0 1 1 1 1 VAD1 Analog of StAR-related lipid transfer domain GRAM PF02893.20 OQR81698.1 - 7.2e-17 61.3 0.1 2.3e-16 59.7 0.1 1.9 1 0 0 1 1 1 1 GRAM domain FCH PF00611.23 OQR81698.1 - 5.3e-13 49.1 15.6 4.3e-08 33.3 0.3 4.8 5 0 0 5 5 5 2 Fes/CIP4, and EFC/F-BAR homology domain APH PF01636.23 OQR81698.1 - 0.0016 18.4 0.1 0.3 10.9 0.0 3.5 3 0 0 3 3 3 1 Phosphotransferase enzyme family Kinase-like PF14531.6 OQR81698.1 - 0.0017 17.7 0.0 0.0043 16.4 0.0 1.6 1 0 0 1 1 1 1 Kinase-like DUF4624 PF15417.6 OQR81698.1 - 0.062 13.1 0.1 0.27 11.1 0.2 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4624) V-SNARE PF05008.15 OQR81698.1 - 0.26 11.7 5.8 0.17 12.3 0.4 3.3 3 0 0 3 3 2 0 Vesicle transport v-SNARE protein N-terminus AI-2E_transport PF01594.16 OQR81698.1 - 0.27 10.4 0.5 0.62 9.2 0.5 1.6 1 0 0 1 1 1 0 AI-2E family transporter RT_RNaseH PF17917.1 OQR81698.1 - 0.4 11.0 2.3 2.4 8.5 0.3 2.9 3 0 0 3 3 3 0 RNase H-like domain found in reverse transcriptase P66_CC PF16563.5 OQR81698.1 - 3.5 7.3 6.4 2.7 7.7 2.8 2.7 1 1 1 2 2 2 0 Coiled-coil and interaction region of P66A and P66B with MBD2 Rotamase PF00639.21 OQR81699.1 - 3.4e-20 72.8 0.1 9.1e-20 71.4 0.1 1.8 1 1 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_3 PF13616.6 OQR81699.1 - 8.5e-17 61.8 1.4 6.6e-16 58.9 0.3 2.5 1 1 1 2 2 2 1 PPIC-type PPIASE domain WW PF00397.26 OQR81699.1 - 1.1e-07 31.8 2.0 2.3e-07 30.8 2.0 1.5 1 0 0 1 1 1 1 WW domain Rotamase_2 PF13145.6 OQR81699.1 - 0.00012 22.9 0.0 0.00024 21.9 0.0 1.6 1 0 0 1 1 1 1 PPIC-type PPIASE domain X8 PF07983.13 OQR81699.1 - 0.025 15.2 0.0 0.044 14.5 0.0 1.3 1 0 0 1 1 1 0 X8 domain PQQ PF01011.21 OQR81699.1 - 0.17 11.9 0.0 0.28 11.2 0.0 1.4 1 0 0 1 1 1 0 PQQ enzyme repeat NAD_binding_1 PF00175.21 OQR81699.1 - 0.41 11.3 4.1 19 6.0 0.0 2.8 1 1 0 2 2 2 0 Oxidoreductase NAD-binding domain TSNAXIP1_N PF15739.5 OQR81700.1 - 2.6e-08 34.2 0.9 3.7e-08 33.7 0.9 1.2 1 0 0 1 1 1 1 Translin-associated factor X-interacting N-terminus RILP PF11461.8 OQR81700.1 - 0.008 16.4 1.3 0.008 16.4 1.3 1.6 2 0 0 2 2 2 1 Rab interacting lysosomal protein MT PF12777.7 OQR81701.1 - 1.1e-06 27.9 0.0 1.6e-06 27.4 0.0 1.1 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor Acyl-CoA_dh_M PF02770.19 OQR81702.1 - 1.1e-17 64.0 0.0 1.9e-17 63.2 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain ACOX PF01756.19 OQR81702.1 - 5.3e-15 55.4 0.0 1e-14 54.5 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA oxidase Acyl-CoA_dh_1 PF00441.24 OQR81702.1 - 5.9e-06 26.6 1.2 0.00019 21.7 0.1 2.3 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Dynamin_N PF00350.23 OQR81703.1 - 1.2e-06 28.7 0.2 0.00018 21.6 0.1 2.0 1 1 1 2 2 2 2 Dynamin family MMR_HSR1 PF01926.23 OQR81703.1 - 7.6e-06 26.0 0.0 8.4e-06 25.9 0.0 1.1 1 0 0 1 1 1 1 50S ribosome-binding GTPase RHD3 PF05879.12 OQR81703.1 - 1.4e-05 23.5 0.0 1.5e-05 23.4 0.0 1.1 1 0 0 1 1 1 1 Root hair defective 3 GTP-binding protein (RHD3) GBP PF02263.19 OQR81703.1 - 0.00043 19.6 0.0 0.00049 19.4 0.0 1.1 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain HECT_2 PF09814.9 OQR81704.1 - 1.1e-38 133.1 0.1 2.2e-38 132.1 0.1 1.5 1 1 0 1 1 1 1 HECT-like Ubiquitin-conjugating enzyme (E2)-binding CS PF04969.16 OQR81704.1 - 0.036 15.1 0.1 0.12 13.4 0.1 2.0 1 0 0 1 1 1 0 CS domain MalF_P2 PF14785.6 OQR81704.1 - 0.063 13.3 0.0 0.17 11.9 0.0 1.7 1 0 0 1 1 1 0 Maltose transport system permease protein MalF P2 domain IFT57 PF10498.9 OQR81704.1 - 0.096 11.6 1.8 0.15 11.0 1.8 1.2 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 Syntaxin-6_N PF09177.11 OQR81704.1 - 0.13 12.8 0.7 0.28 11.8 0.7 1.5 1 0 0 1 1 1 0 Syntaxin 6, N-terminal She9_MDM33 PF05546.11 OQR81704.1 - 0.15 11.8 2.0 0.27 11.0 2.0 1.3 1 0 0 1 1 1 0 She9 / Mdm33 family ERp29 PF07749.12 OQR81704.1 - 0.21 12.5 1.6 0.42 11.5 1.6 1.5 1 0 0 1 1 1 0 Endoplasmic reticulum protein ERp29, C-terminal domain Phage_GPO PF05929.11 OQR81704.1 - 0.22 11.1 2.3 0.48 10.0 2.3 1.5 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase Tnp_P_element PF12017.8 OQR81705.1 - 0.0077 15.7 0.0 0.0096 15.4 0.0 1.1 1 0 0 1 1 1 1 Transposase protein Sugar_tr PF00083.24 OQR81706.1 - 2.8e-38 132.0 20.8 3.5e-38 131.6 20.8 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OQR81706.1 - 1.9e-32 112.6 39.5 1e-25 90.5 16.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 OQR81706.1 - 0.0047 15.3 4.0 0.0055 15.1 2.7 1.6 1 1 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family MFS_4 PF06779.14 OQR81706.1 - 0.96 8.7 27.0 0.014 14.7 9.9 2.1 2 0 0 2 2 2 0 Uncharacterised MFS-type transporter YbfB FHA PF00498.26 OQR81707.1 - 3.9e-11 43.1 0.0 5.3e-11 42.7 0.0 1.2 1 0 0 1 1 1 1 FHA domain FHA_2 PF17913.1 OQR81707.1 - 0.0043 17.3 0.0 0.56 10.5 0.0 2.2 2 0 0 2 2 2 2 FHA domain YmaF PF12788.7 OQR81707.1 - 0.042 14.4 0.0 0.066 13.8 0.0 1.3 1 0 0 1 1 1 0 YmaF family HR1 PF02185.16 OQR81708.1 - 0.0068 16.5 3.3 0.0068 16.5 3.3 4.5 4 1 1 5 5 5 2 Hr1 repeat HEPN_SAV_6107 PF18726.1 OQR81708.1 - 0.019 15.4 0.0 15 6.1 0.0 3.1 3 0 0 3 3 3 0 SAV_6107-like HEPN Pox_A_type_inc PF04508.12 OQR81708.1 - 0.037 13.9 1.0 11 6.1 0.0 3.1 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat WD40_alt PF14077.6 OQR81708.1 - 2.9 7.8 4.4 2.6 8.0 0.3 2.8 3 0 0 3 3 3 0 Alternative WD40 repeat motif DUF569 PF04601.13 OQR81709.1 - 0.009 15.7 0.0 0.018 14.7 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF569) Na_trans_assoc PF06512.13 OQR81709.1 - 0.059 13.7 2.2 0.11 12.7 2.2 1.5 1 0 0 1 1 1 0 Sodium ion transport-associated Mt_ATP-synt_B PF05405.14 OQR81710.1 - 0.34 10.5 2.6 0.49 10.0 0.6 2.1 2 0 0 2 2 2 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) HECT PF00632.25 OQR81711.1 - 1.5e-81 274.2 0.0 2e-81 273.8 0.0 1.1 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) zf-RanBP PF00641.18 OQR81711.1 - 0.00036 19.8 1.7 0.00072 18.8 1.7 1.5 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others zf-Sec23_Sec24 PF04810.15 OQR81711.1 - 0.21 11.7 1.1 0.33 11.0 0.3 1.8 1 1 0 1 1 1 0 Sec23/Sec24 zinc finger Gtr1_RagA PF04670.12 OQR81712.1 - 1.1e-63 214.7 1.3 1.6e-63 214.2 1.3 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region UQ_con PF00179.26 OQR81712.1 - 8.5e-27 93.5 0.0 1.9e-26 92.4 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme MMR_HSR1 PF01926.23 OQR81712.1 - 0.17 12.0 0.0 0.36 10.9 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase ADH_zinc_N_2 PF13602.6 OQR81713.1 - 6.5e-17 62.8 0.0 1.4e-16 61.7 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 OQR81713.1 - 3.7e-14 52.8 0.1 6.2e-14 52.1 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 OQR81713.1 - 5.3e-10 39.1 0.0 1.5e-09 37.7 0.0 1.7 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ELFV_dehydrog PF00208.21 OQR81713.1 - 0.036 13.8 0.1 0.053 13.2 0.1 1.2 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase PP2C PF00481.21 OQR81714.1 - 4.7e-46 157.5 0.7 1.2e-44 152.9 0.7 2.6 1 1 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 OQR81714.1 - 0.00071 19.3 0.1 0.001 18.7 0.1 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C HTH_23 PF13384.6 OQR81714.1 - 0.16 11.8 0.0 0.47 10.3 0.0 1.8 1 0 0 1 1 1 0 Homeodomain-like domain Carb_anhydrase PF00194.21 OQR81715.1 - 2.5e-38 132.1 0.0 4.4e-38 131.3 0.0 1.3 1 1 0 1 1 1 1 Eukaryotic-type carbonic anhydrase SmaI PF17411.2 OQR81715.1 - 0.047 12.9 0.0 0.086 12.0 0.0 1.3 1 0 0 1 1 1 0 Type II site-specific deoxyribonuclease ABC_tran PF00005.27 OQR81716.1 - 1.8e-09 38.2 0.1 3.8e-09 37.2 0.0 1.5 2 0 0 2 2 2 1 ABC transporter SMC_N PF02463.19 OQR81716.1 - 7.9e-05 22.2 0.1 0.0001 21.8 0.1 1.1 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain ETC_C1_NDUFA5 PF04716.14 OQR81716.1 - 0.21 11.4 1.6 1.4 8.8 0.2 2.1 1 1 1 2 2 2 0 ETC complex I subunit conserved region ABC_membrane PF00664.23 OQR81717.1 - 3.6e-19 69.5 4.7 4.5e-19 69.2 4.7 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region Pex24p PF06398.11 OQR81717.1 - 0.045 12.7 1.1 0.056 12.4 1.1 1.3 1 1 0 1 1 1 0 Integral peroxisomal membrane peroxin HA PF03457.14 OQR81718.1 - 3.1e-33 113.9 1.0 1.5e-08 34.8 0.0 5.0 4 1 1 5 5 5 4 Helicase associated domain Aa_trans PF01490.18 OQR81719.1 - 6.6e-36 123.9 28.4 7.4e-36 123.7 28.4 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein SPC12 PF06645.13 OQR81719.1 - 0.023 14.8 0.4 0.023 14.8 0.4 4.7 6 2 0 6 6 6 0 Microsomal signal peptidase 12 kDa subunit (SPC12) DUF412 PF04217.13 OQR81719.1 - 2.8 7.8 5.7 0.78 9.6 0.8 2.3 1 1 1 2 2 2 0 Protein of unknown function, DUF412 zf-RING_2 PF13639.6 OQR81720.1 - 8.8e-14 51.6 4.3 2.5e-13 50.1 4.3 1.8 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 OQR81720.1 - 1e-08 35.3 6.1 3.2e-08 33.7 6.1 2.0 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 OQR81720.1 - 1.5e-08 34.4 4.0 3.1e-08 33.3 4.0 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OQR81720.1 - 2.2e-08 33.9 3.0 5.7e-08 32.6 3.0 1.8 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 OQR81720.1 - 6.3e-08 32.5 0.3 6.3e-08 32.5 0.3 2.4 1 1 1 2 2 2 1 RING-type zinc-finger zf-RING_11 PF17123.5 OQR81720.1 - 3.3e-07 29.9 2.1 3.3e-07 29.9 2.1 2.3 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4_3 PF13920.6 OQR81720.1 - 3e-06 27.0 4.2 6.2e-06 26.0 4.2 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 OQR81720.1 - 4.7e-05 22.9 4.1 9.5e-05 21.9 4.1 1.5 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zinc_ribbon_16 PF17034.5 OQR81720.1 - 0.00014 22.1 5.3 0.00041 20.5 5.3 1.9 1 1 0 1 1 1 1 Zinc-ribbon like family zf-ANAPC11 PF12861.7 OQR81720.1 - 0.00024 21.1 6.4 0.0018 18.3 6.4 2.2 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4 PF00097.25 OQR81720.1 - 0.00081 19.2 8.8 0.002 17.9 8.8 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3H2C3 PF17122.5 OQR81720.1 - 0.016 15.2 3.2 0.051 13.6 3.2 2.0 1 0 0 1 1 1 0 Zinc-finger Prok-RING_4 PF14447.6 OQR81720.1 - 0.02 14.7 9.7 0.031 14.1 8.1 2.0 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 OQR81720.1 - 0.023 14.9 3.5 0.11 12.7 3.7 2.1 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-Nse PF11789.8 OQR81720.1 - 0.039 13.8 0.5 0.081 12.8 0.5 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit PX PF00787.24 OQR81720.1 - 0.054 13.5 0.2 0.083 12.9 0.2 1.4 1 0 0 1 1 1 0 PX domain FANCL_C PF11793.8 OQR81720.1 - 0.7 10.1 7.0 4.1 7.6 7.0 2.3 1 1 0 1 1 1 0 FANCL C-terminal domain Abhydrolase_6 PF12697.7 OQR81721.1 - 1.5e-11 45.3 0.2 1.9e-11 45.0 0.2 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 OQR81721.1 - 7.9e-06 25.3 0.0 1.2e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 OQR81721.1 - 0.00031 20.5 0.0 0.0004 20.1 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Pyrophosphatase PF00719.19 OQR81722.1 - 7.5e-45 152.6 1.1 1e-44 152.2 0.1 1.7 2 0 0 2 2 2 1 Inorganic pyrophosphatase PH PF00169.29 OQR81722.1 - 1.2e-15 57.9 0.4 2.7e-15 56.8 0.4 1.6 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 OQR81722.1 - 8e-08 32.7 1.9 1.7e-06 28.4 1.9 2.5 1 1 0 1 1 1 1 Pleckstrin homology domain EF-hand_7 PF13499.6 OQR81722.1 - 8.1e-06 26.2 0.0 2.4e-05 24.7 0.0 1.8 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 OQR81722.1 - 3.1e-05 23.5 0.0 0.00011 21.9 0.0 2.0 1 0 0 1 1 1 1 EF-hand domain EF-hand_1 PF00036.32 OQR81722.1 - 0.00015 21.0 0.1 0.00057 19.2 0.0 2.0 2 0 0 2 2 2 1 EF hand EF-hand_5 PF13202.6 OQR81722.1 - 0.0031 16.9 0.0 0.0076 15.7 0.0 1.7 1 0 0 1 1 1 1 EF hand Dockerin_1 PF00404.18 OQR81722.1 - 0.1 12.8 0.3 0.29 11.3 0.0 1.9 2 0 0 2 2 2 0 Dockerin type I domain RCC1 PF00415.18 OQR81723.1 - 5.7e-61 202.9 23.6 2.6e-13 50.4 0.0 8.0 8 0 0 8 8 8 6 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 OQR81723.1 - 1.5e-34 117.0 34.8 2.5e-08 33.5 0.2 8.0 8 0 0 8 8 8 6 Regulator of chromosome condensation (RCC1) repeat DUF937 PF06078.11 OQR81723.1 - 0.06 14.0 0.0 0.16 12.6 0.0 1.6 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF937) Ank_2 PF12796.7 OQR81724.1 - 7.6e-27 93.7 2.1 1.9e-09 38.0 0.2 3.0 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQR81724.1 - 1.5e-26 92.4 5.3 4.7e-06 27.0 0.1 5.6 4 2 2 6 6 6 5 Ankyrin repeats (many copies) DHHC PF01529.20 OQR81724.1 - 1.6e-26 93.0 3.7 1.6e-26 93.0 3.7 3.1 4 0 0 4 4 4 1 DHHC palmitoyltransferase Ank_5 PF13857.6 OQR81724.1 - 8.4e-20 70.6 7.2 7.3e-07 29.3 0.1 4.6 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQR81724.1 - 6.9e-18 62.9 6.8 4.5e-05 23.5 0.0 6.6 6 0 0 6 6 6 3 Ankyrin repeat Ank PF00023.30 OQR81724.1 - 4e-11 42.8 7.0 0.00027 21.3 0.1 4.8 5 0 0 5 5 5 3 Ankyrin repeat HECT PF00632.25 OQR81725.1 - 1.4e-96 323.6 0.0 2.6e-96 322.7 0.0 1.4 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) DUF913 PF06025.12 OQR81725.1 - 1.6e-25 89.9 6.6 8.2e-21 74.4 0.0 4.2 2 1 1 3 3 3 2 Domain of Unknown Function (DUF913) UBM PF14377.6 OQR81725.1 - 3.9e-20 70.6 17.8 9.5e-07 28.1 0.6 5.0 3 1 1 4 4 4 4 Ubiquitin binding region UBA PF00627.31 OQR81725.1 - 0.00059 19.7 0.1 0.0014 18.5 0.1 1.7 1 0 0 1 1 1 1 UBA/TS-N domain DUF1824 PF08854.10 OQR81725.1 - 0.0035 17.2 0.1 0.0089 15.9 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1824) SDA1 PF05285.12 OQR81725.1 - 0.17 11.3 26.5 0.37 10.2 26.5 1.5 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 OQR81725.1 - 0.28 9.3 26.6 0.68 8.1 26.6 1.6 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 OQR81725.1 - 0.46 8.7 19.2 0.8 7.9 19.2 1.3 1 0 0 1 1 1 0 CDC45-like protein SAPS PF04499.15 OQR81725.1 - 2.9 6.6 9.6 0.21 10.3 3.4 2.1 2 0 0 2 2 2 0 SIT4 phosphatase-associated protein DNA_pol_phi PF04931.13 OQR81725.1 - 5.4 5.0 34.3 20 3.1 34.3 2.0 1 0 0 1 1 1 0 DNA polymerase phi Tim54 PF11711.8 OQR81725.1 - 6.8 5.4 9.7 14 4.3 9.7 1.4 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 UCH PF00443.29 OQR81726.1 - 1.4e-70 237.7 0.0 2.7e-70 236.8 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase PX PF00787.24 OQR81726.1 - 1.9e-16 60.0 0.4 4.5e-16 58.8 0.4 1.6 1 0 0 1 1 1 1 PX domain UCH_1 PF13423.6 OQR81726.1 - 2.7e-16 60.0 0.0 2.1e-08 34.1 0.0 2.7 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.12 OQR81726.1 - 2.8e-13 50.3 0.1 9.3e-13 48.6 0.1 2.0 1 0 0 1 1 1 1 DUSP domain Agenet PF05641.12 OQR81726.1 - 0.015 15.7 0.0 0.035 14.6 0.0 1.6 1 0 0 1 1 1 0 Agenet domain EF-hand_7 PF13499.6 OQR81726.1 - 0.22 12.0 1.3 16 6.0 0.1 3.8 4 0 0 4 4 4 0 EF-hand domain pair D123 PF07065.14 OQR81727.1 - 2.2e-78 263.5 2.7 4.5e-74 249.4 1.3 2.1 1 1 1 2 2 2 2 D123 Pkinase PF00069.25 OQR81728.1 - 1e-32 113.5 0.0 1.4e-32 113.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQR81728.1 - 1.2e-27 96.9 0.0 1.6e-27 96.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OQR81728.1 - 0.11 11.8 0.0 0.2 10.9 0.0 1.4 1 0 0 1 1 1 0 Kinase-like Ank_2 PF12796.7 OQR81729.1 - 5.8e-39 132.6 0.9 2.9e-14 53.4 0.0 5.5 3 1 2 5 5 5 5 Ankyrin repeats (3 copies) Ank PF00023.30 OQR81729.1 - 1.5e-32 110.6 7.3 0.00085 19.7 0.0 8.4 8 0 0 8 8 8 7 Ankyrin repeat Ank_4 PF13637.6 OQR81729.1 - 3.5e-31 107.2 1.5 2.1e-10 40.9 0.0 6.7 4 1 3 7 7 7 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQR81729.1 - 8.3e-31 102.6 3.5 3.1e-05 24.0 0.0 8.2 8 0 0 8 8 8 6 Ankyrin repeat Ank_5 PF13857.6 OQR81729.1 - 1.1e-29 102.0 3.7 8.8e-11 41.8 0.0 6.7 5 1 1 6 6 6 5 Ankyrin repeats (many copies) WD40 PF00400.32 OQR81729.1 - 1.8e-14 53.9 20.0 0.035 15.0 0.2 6.6 6 0 0 6 6 6 5 WD domain, G-beta repeat TIR_2 PF13676.6 OQR81729.1 - 3.7e-11 43.7 0.0 4.1e-08 33.8 0.0 2.8 2 0 0 2 2 2 2 TIR domain ANAPC4_WD40 PF12894.7 OQR81729.1 - 0.00019 21.7 2.5 0.066 13.5 0.1 4.2 3 1 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 OQR81729.1 - 0.044 12.7 0.3 1.6 7.6 0.0 2.9 1 1 1 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein PH PF00169.29 OQR81730.1 - 5.3e-13 49.4 0.0 1e-12 48.5 0.0 1.5 1 0 0 1 1 1 1 PH domain GBP PF02263.19 OQR81730.1 - 9e-10 38.2 0.0 2.4e-09 36.9 0.0 1.6 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain GBP_C PF02841.14 OQR81730.1 - 2.9e-07 30.2 2.2 5.5e-07 29.3 2.2 1.4 1 0 0 1 1 1 1 Guanylate-binding protein, C-terminal domain PH_11 PF15413.6 OQR81730.1 - 9.5e-05 22.8 0.3 0.00036 20.9 0.3 2.0 1 1 0 1 1 1 1 Pleckstrin homology domain DUF16 PF01519.16 OQR81730.1 - 0.35 11.4 3.5 1.3 9.5 3.5 2.0 1 0 0 1 1 1 0 Protein of unknown function DUF16 Complex1_LYR PF05347.15 OQR81731.1 - 1.1e-12 47.8 1.1 1.4e-12 47.5 1.1 1.2 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 OQR81731.1 - 0.00098 19.8 0.9 0.0011 19.6 0.9 1.1 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR_1 PF13232.6 OQR81731.1 - 0.0037 17.8 0.1 0.0043 17.6 0.1 1.2 1 0 0 1 1 1 1 Complex1_LYR-like RNase_PH PF01138.21 OQR81732.1 - 5.8e-12 46.3 0.0 1e-11 45.4 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 OQR81732.1 - 4.1e-05 23.5 0.0 0.0087 16.1 0.0 2.7 1 1 0 1 1 1 1 3' exoribonuclease family, domain 2 OsmC PF02566.19 OQR81733.1 - 1.6e-07 31.7 0.0 2.7e-07 31.0 0.0 1.4 1 0 0 1 1 1 1 OsmC-like protein Crp PF00325.20 OQR81733.1 - 0.17 11.6 0.1 0.42 10.3 0.1 1.7 1 0 0 1 1 1 0 Bacterial regulatory proteins, crp family Ion_trans PF00520.31 OQR81734.1 - 6.7e-52 176.1 30.7 8.4e-43 146.4 18.0 2.1 2 0 0 2 2 2 2 Ion transport protein PKD_channel PF08016.12 OQR81734.1 - 2.5e-06 26.4 30.1 7.3e-06 24.9 9.8 3.5 3 1 1 4 4 4 3 Polycystin cation channel EF-hand_6 PF13405.6 OQR81734.1 - 0.033 14.1 0.0 0.11 12.5 0.0 1.9 1 0 0 1 1 1 0 EF-hand domain EF-hand_1 PF00036.32 OQR81734.1 - 0.046 13.3 0.0 0.13 11.9 0.0 1.8 1 0 0 1 1 1 0 EF hand DUF1579 PF07617.11 OQR81734.1 - 0.12 12.3 0.1 32 4.4 0.2 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF1579) Lung_7-TM_R PF06814.13 OQR81737.1 - 2.8e-38 131.9 5.9 3.7e-38 131.4 5.9 1.1 1 0 0 1 1 1 1 Lung seven transmembrane receptor DUF3087 PF11286.8 OQR81737.1 - 0.25 10.8 0.9 2.7 7.4 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3087) ERM PF00769.19 OQR81739.1 - 0.021 14.6 14.1 0.025 14.4 14.1 1.1 1 0 0 1 1 1 0 Ezrin/radixin/moesin family MIF4G_like_2 PF09090.11 OQR81739.1 - 0.082 12.4 5.7 0.12 11.8 5.7 1.2 1 0 0 1 1 1 0 MIF4G like Atg14 PF10186.9 OQR81739.1 - 0.42 9.6 7.5 0.6 9.1 7.5 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 APG6_N PF17675.1 OQR81739.1 - 1.2 9.6 15.3 1.9 9.0 15.3 1.2 1 0 0 1 1 1 0 Apg6 coiled-coil region CENP-Q PF13094.6 OQR81739.1 - 1.6 8.9 16.0 3.9 7.7 15.9 1.6 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit Acetyltransf_11 PF13720.6 OQR81739.1 - 3 8.4 5.3 2.7 8.5 2.5 2.3 2 1 1 3 3 3 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 WGR PF05406.15 OQR81740.1 - 2.4e-11 43.5 1.1 4.7e-10 39.4 0.0 2.9 3 1 0 3 3 3 1 WGR domain WWE PF02825.20 OQR81740.1 - 3.1e-11 43.7 2.4 5.1e-09 36.6 0.6 2.6 2 0 0 2 2 2 2 WWE domain CRAL_TRIO PF00650.20 OQR81741.1 - 1.9e-56 190.1 1.7 3.2e-30 104.9 0.0 3.6 2 2 1 3 3 3 3 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 OQR81741.1 - 1.8e-12 47.6 0.3 1.7e-05 25.0 0.0 2.2 2 0 0 2 2 2 2 Divergent CRAL/TRIO domain CRAL_TRIO_N PF03765.15 OQR81741.1 - 2.7e-05 24.3 2.7 2.9e-05 24.2 0.5 2.2 3 0 0 3 3 3 1 CRAL/TRIO, N-terminal domain Peptidase_S3 PF00944.19 OQR81741.1 - 0.0026 17.6 0.0 1.3 8.8 0.0 2.3 2 0 0 2 2 2 2 Alphavirus core protein DENN PF02141.21 OQR81742.1 - 3.3e-23 82.6 1.1 7.7e-23 81.4 1.1 1.5 1 0 0 1 1 1 1 DENN (AEX-3) domain Abhydrolase_6 PF12697.7 OQR81743.1 - 3e-10 41.1 0.1 5.3e-10 40.3 0.1 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 OQR81743.1 - 2.6e-08 33.5 0.0 3.8e-08 32.9 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 OQR81743.1 - 3.9e-08 33.3 1.6 4.3e-08 33.1 0.1 1.8 2 0 0 2 2 2 1 alpha/beta hydrolase fold PH PF00169.29 OQR81743.1 - 9.5e-05 22.9 0.0 0.00018 21.9 0.0 1.5 1 0 0 1 1 1 1 PH domain Thioesterase PF00975.20 OQR81743.1 - 0.0089 16.2 0.0 0.019 15.1 0.0 1.5 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_3 PF07859.13 OQR81743.1 - 0.013 15.4 0.0 0.02 14.7 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Abhydro_lipase PF04083.16 OQR81743.1 - 0.18 11.4 0.4 0.77 9.4 0.0 2.2 3 0 0 3 3 3 0 Partial alpha/beta-hydrolase lipase region PAPS_reduct PF01507.19 OQR81744.1 - 4e-48 163.7 0.0 5.7e-48 163.2 0.0 1.2 1 0 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family Glutaredoxin PF00462.24 OQR81744.1 - 4.3e-13 49.3 2.1 2.7e-12 46.7 0.6 2.5 2 0 0 2 2 2 1 Glutaredoxin DUF836 PF05768.14 OQR81744.1 - 2.7e-05 24.5 0.5 6.4e-05 23.3 0.5 1.7 1 0 0 1 1 1 1 Glutaredoxin-like domain (DUF836) GST_N_3 PF13417.6 OQR81744.1 - 0.005 17.2 0.0 0.011 16.1 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Casc1_N PF15927.5 OQR81745.1 - 6.3e-35 120.7 14.1 6.3e-35 120.7 14.1 2.6 2 1 1 3 3 3 1 Cancer susceptibility candidate 1 N-terminus MoaF PF10703.9 OQR81745.1 - 0.096 12.6 0.0 0.25 11.3 0.0 1.6 1 0 0 1 1 1 0 MoaF N-terminal domain Ribosomal_S24e PF01282.19 OQR81746.1 - 2e-35 120.6 1.1 6.1e-35 119.0 0.0 2.0 1 1 1 2 2 2 1 Ribosomal protein S24e ORC5_C PF14630.6 OQR81747.1 - 1.8e-49 168.8 0.3 2.7e-49 168.2 0.3 1.3 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 5 C-terminus Macro PF01661.21 OQR81747.1 - 5.7e-37 126.4 0.0 1.2e-36 125.3 0.0 1.6 1 0 0 1 1 1 1 Macro domain AAA_16 PF13191.6 OQR81747.1 - 6.3e-09 36.4 0.0 1.4e-08 35.3 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 OQR81747.1 - 5.2e-05 23.5 0.4 0.00016 21.9 0.0 2.0 3 0 0 3 3 3 1 AAA domain ATPase_2 PF01637.18 OQR81747.1 - 0.16 11.8 0.0 0.35 10.7 0.0 1.5 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea SNARE PF05739.19 OQR81748.1 - 1.6e-05 24.8 0.2 3e-05 23.9 0.2 1.4 1 0 0 1 1 1 1 SNARE domain Tropomyosin PF00261.20 OQR81748.1 - 0.0034 16.8 0.5 0.0044 16.4 0.5 1.1 1 0 0 1 1 1 1 Tropomyosin Cas_NE0113 PF09623.10 OQR81748.1 - 0.04 13.6 0.1 0.051 13.3 0.1 1.2 1 0 0 1 1 1 0 CRISPR-associated protein NE0113 (Cas_NE0113) RasGAP_C PF03836.15 OQR81748.1 - 0.055 13.6 1.5 0.076 13.2 1.5 1.2 1 0 0 1 1 1 0 RasGAP C-terminus Lebercilin PF15619.6 OQR81748.1 - 0.07 12.8 3.3 0.085 12.5 3.3 1.1 1 0 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease DUF16 PF01519.16 OQR81748.1 - 0.085 13.4 2.3 0.11 13.0 2.3 1.2 1 0 0 1 1 1 0 Protein of unknown function DUF16 Sec20 PF03908.13 OQR81748.1 - 0.74 9.8 4.0 2.1 8.3 4.0 1.9 1 1 0 1 1 1 0 Sec20 Lung_7-TM_R PF06814.13 OQR81749.1 - 2.2e-45 155.2 13.3 3.1e-45 154.7 13.3 1.2 1 0 0 1 1 1 1 Lung seven transmembrane receptor Ost5 PF05251.12 OQR81749.1 - 0.35 11.2 5.9 1.3 9.4 0.8 3.1 2 0 0 2 2 2 0 Oligosaccharyltransferase subunit 5 Ribosomal_L39 PF00832.20 OQR81750.1 - 2.6e-22 78.2 9.0 3.7e-22 77.7 9.0 1.2 1 0 0 1 1 1 1 Ribosomal L39 protein EGF_2 PF07974.13 OQR81750.1 - 2.2e-05 24.7 51.7 0.00094 19.5 10.3 4.8 3 1 1 4 4 4 2 EGF-like domain EGF PF00008.27 OQR81750.1 - 0.002 18.4 2.6 0.002 18.4 2.6 4.0 3 0 0 3 3 3 2 EGF-like domain hEGF PF12661.7 OQR81750.1 - 0.018 15.7 4.6 0.018 15.7 4.6 5.5 5 1 1 6 6 6 0 Human growth factor-like EGF Laminin_EGF PF00053.24 OQR81750.1 - 0.042 14.0 46.3 0.064 13.4 15.9 4.0 2 1 2 4 4 4 0 Laminin EGF domain Pkinase_Tyr PF07714.17 OQR81751.1 - 3.1e-75 252.8 0.0 1.7e-32 112.7 0.0 3.3 2 1 1 3 3 3 3 Protein tyrosine kinase Pkinase PF00069.25 OQR81751.1 - 5.3e-75 252.2 0.0 7.5e-30 104.2 0.0 3.1 2 1 1 3 3 3 3 Protein kinase domain Haspin_kinase PF12330.8 OQR81751.1 - 1.2e-05 24.5 0.4 0.063 12.2 0.0 2.9 3 0 0 3 3 3 2 Haspin like kinase domain EphA2_TM PF14575.6 OQR81751.1 - 7.2e-05 23.6 0.0 0.27 12.1 0.0 2.5 2 0 0 2 2 2 2 Ephrin type-A receptor 2 transmembrane domain Herpes_gE PF02480.16 OQR81751.1 - 0.00064 18.6 0.0 0.058 12.1 0.0 2.1 2 0 0 2 2 2 1 Alphaherpesvirus glycoprotein E DUF4381 PF14316.6 OQR81751.1 - 0.0013 19.0 0.7 0.71 10.1 0.1 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4381) APH PF01636.23 OQR81751.1 - 0.0016 18.4 0.0 1.4 8.8 0.0 2.4 2 0 0 2 2 2 2 Phosphotransferase enzyme family Adeno_E3_CR2 PF02439.15 OQR81751.1 - 0.0025 17.5 0.1 0.98 9.2 0.0 2.6 2 0 0 2 2 2 1 Adenovirus E3 region protein CR2 DUF4448 PF14610.6 OQR81751.1 - 0.0034 17.2 0.0 0.73 9.6 0.0 2.9 2 1 0 2 2 2 1 Protein of unknown function (DUF4448) LapA_dom PF06305.11 OQR81751.1 - 0.0039 17.0 3.8 0.71 9.7 0.2 2.5 2 0 0 2 2 2 2 Lipopolysaccharide assembly protein A domain Spore_YhaL PF14147.6 OQR81751.1 - 0.0062 16.2 0.5 4.4 7.1 0.0 3.0 2 0 0 2 2 2 1 Sporulation protein YhaL MASE1 PF05231.14 OQR81751.1 - 0.016 14.4 0.0 0.16 11.1 0.0 2.0 2 0 0 2 2 2 0 MASE1 Protocadherin PF08374.11 OQR81751.1 - 0.026 14.5 0.0 0.86 9.5 0.0 2.4 2 0 0 2 2 2 0 Protocadherin NKAIN PF05640.14 OQR81751.1 - 0.059 12.6 0.0 10 5.3 0.0 2.4 2 0 0 2 2 2 0 Na,K-Atpase Interacting protein DUF2207 PF09972.9 OQR81751.1 - 0.061 12.1 0.0 0.25 10.1 0.0 1.8 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) DDE_Tnp_1_7 PF13843.6 OQR81751.1 - 0.083 12.2 0.1 2.3 7.5 0.0 2.1 2 0 0 2 2 2 0 Transposase IS4 Rax2 PF12768.7 OQR81751.1 - 0.096 12.1 0.1 0.59 9.6 0.1 2.1 2 0 0 2 2 2 0 Cortical protein marker for cell polarity DUF4307 PF14155.6 OQR81751.1 - 0.099 12.5 0.0 1.2 9.0 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4307) Ni_hydr_CYTB PF01292.20 OQR81751.1 - 0.11 12.1 0.0 2.5 7.6 0.0 2.2 2 0 0 2 2 2 0 Prokaryotic cytochrome b561 PAP_PilO PF06864.12 OQR81751.1 - 0.12 11.1 0.0 4.6 6.0 0.0 2.1 2 0 0 2 2 2 0 Pilin accessory protein (PilO) Cadherin_C_2 PF16492.5 OQR81751.1 - 0.14 12.9 0.0 0.74 10.6 0.0 2.1 2 0 0 2 2 2 0 Cadherin cytoplasmic C-terminal TMEMspv1-c74-12 PF11044.8 OQR81751.1 - 0.16 12.0 4.6 4.6 7.3 0.2 3.5 3 0 0 3 3 3 0 Plectrovirus spv1-c74 ORF 12 transmembrane protein DUF4051 PF13260.6 OQR81751.1 - 0.27 11.0 3.7 10 5.9 1.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4051) CcmD PF04995.14 OQR81751.1 - 3 8.0 9.6 8.9 6.5 3.2 2.6 2 0 0 2 2 2 0 Heme exporter protein D (CcmD) RCR PF12273.8 OQR81751.1 - 3.2 8.4 6.2 30 5.3 0.0 2.7 2 1 0 2 2 2 0 Chitin synthesis regulation, resistance to Congo red DnaJ PF00226.31 OQR81752.1 - 9.8e-23 80.1 0.2 1.2e-22 79.8 0.2 1.1 1 0 0 1 1 1 1 DnaJ domain DnaJ_C PF01556.18 OQR81753.1 - 1.7e-30 106.1 0.3 2.2e-30 105.7 0.3 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 OQR81753.1 - 2.8e-23 81.8 0.2 4.3e-23 81.2 0.2 1.3 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 OQR81753.1 - 1.3e-15 57.5 18.6 2.1e-15 56.8 18.6 1.4 1 0 0 1 1 1 1 DnaJ central domain HypA PF01155.19 OQR81753.1 - 0.011 15.7 6.1 0.75 9.8 1.6 2.5 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DZR PF12773.7 OQR81753.1 - 0.19 11.8 7.5 2.2 8.4 1.5 2.3 2 0 0 2 2 2 0 Double zinc ribbon Anti-TRAP PF15777.5 OQR81753.1 - 0.96 9.5 14.9 0.5 10.4 2.4 2.8 1 1 2 3 3 3 0 Tryptophan RNA-binding attenuator protein inhibitory protein DUF2614 PF11023.8 OQR81753.1 - 1.5 8.9 4.4 0.82 9.8 0.5 2.1 2 0 0 2 2 2 0 Zinc-ribbon containing domain zf-RING_10 PF16685.5 OQR81753.1 - 3.6 7.8 7.9 0.32 11.2 1.6 2.1 1 1 1 2 2 2 0 zinc RING finger of MSL2 zinc-ribbons_6 PF07191.12 OQR81753.1 - 5.5 7.0 8.6 10 6.2 2.1 2.3 1 1 1 2 2 2 0 zinc-ribbons Lar_restr_allev PF14354.6 OQR81753.1 - 6.5 7.2 7.6 5.3 7.5 4.6 2.4 2 1 1 3 3 3 0 Restriction alleviation protein Lar Pkinase_Tyr PF07714.17 OQR81754.1 - 4.1e-231 763.7 0.0 2.8e-57 194.0 0.0 5.1 4 1 1 5 5 5 5 Protein tyrosine kinase Pkinase PF00069.25 OQR81754.1 - 9.2e-225 743.1 0.0 2.8e-59 200.6 0.0 5.2 4 1 1 5 5 5 5 Protein kinase domain Kinase-like PF14531.6 OQR81754.1 - 4.4e-26 91.9 0.0 7.1e-06 25.5 0.0 5.3 5 0 0 5 5 5 5 Kinase-like C2 PF00168.30 OQR81754.1 - 5.2e-21 74.9 0.1 4.2e-05 23.8 0.1 4.5 4 0 0 4 4 4 3 C2 domain Pkinase_fungal PF17667.1 OQR81754.1 - 3e-18 65.8 1.4 9.6e-05 21.3 0.0 4.4 5 0 0 5 5 5 3 Fungal protein kinase YrbL-PhoP_reg PF10707.9 OQR81754.1 - 1e-10 41.5 4.5 0.062 12.8 0.1 5.2 5 0 0 5 5 5 3 PhoP regulatory network protein YrbL Kdo PF06293.14 OQR81754.1 - 8.6e-10 38.3 8.5 0.023 14.0 0.2 5.1 5 0 0 5 5 5 4 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OQR81754.1 - 6.6e-07 29.5 1.2 0.4 10.6 0.1 4.1 4 0 0 4 4 4 3 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 OQR81754.1 - 6.6e-07 28.7 0.6 4.9 6.1 0.0 5.2 5 0 0 5 5 5 3 Seadornavirus VP7 Haspin_kinase PF12330.8 OQR81754.1 - 1.9e-05 23.8 9.1 0.052 12.5 0.1 4.5 4 1 0 4 4 4 3 Haspin like kinase domain Pox_ser-thr_kin PF05445.11 OQR81754.1 - 0.014 14.4 7.0 5.1 5.9 0.1 3.7 4 0 0 4 4 4 0 Poxvirus serine/threonine protein kinase Cu-binding_MopE PF11617.8 OQR81754.1 - 5.5 7.2 5.3 33 4.8 0.2 3.3 3 0 0 3 3 3 0 Putative metal-binding motif PAN_4 PF14295.6 OQR81755.1 - 3.3e-06 26.9 6.8 3.4e-06 26.9 3.8 2.7 2 0 0 2 2 2 1 PAN domain MetallophosN PF16371.5 OQR81755.1 - 0.00012 22.3 0.1 0.0018 18.5 0.0 2.5 2 0 0 2 2 2 1 N terminal of Calcineurin-like phosphoesterase PIH1 PF08190.12 OQR81755.1 - 0.48 9.9 1.6 7.3 6.0 0.0 2.2 2 0 0 2 2 2 0 PIH1 N-terminal domain Trypsin_2 PF13365.6 OQR81756.1 - 1.3e-15 58.6 0.0 2.6e-14 54.4 0.0 2.5 1 1 0 1 1 1 1 Trypsin-like peptidase domain FYVE PF01363.21 OQR81756.1 - 8.3e-13 48.3 16.3 1.6e-12 47.4 16.3 1.5 1 0 0 1 1 1 1 FYVE zinc finger SAM_1 PF00536.30 OQR81756.1 - 1.2e-08 35.2 0.0 3.6e-08 33.7 0.0 1.8 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 OQR81756.1 - 9.6e-06 25.6 0.0 3.3e-05 23.9 0.0 2.0 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Trypsin PF00089.26 OQR81756.1 - 0.00017 21.5 0.0 0.0011 18.8 0.0 2.0 1 1 0 1 1 1 1 Trypsin F-box-like PF12937.7 OQR81756.1 - 0.00084 19.2 1.2 0.002 18.0 1.2 1.6 1 0 0 1 1 1 1 F-box-like Mob_synth_C PF06463.13 OQR81756.1 - 0.54 10.2 3.2 1.2 9.0 3.2 1.5 1 0 0 1 1 1 0 Molybdenum Cofactor Synthesis C zf-RING_2 PF13639.6 OQR81756.1 - 2.7 8.4 11.2 6.5 7.2 11.2 1.7 1 0 0 1 1 1 0 Ring finger domain Med17 PF10156.9 OQR81758.1 - 0.0014 17.5 2.1 0.0014 17.5 2.1 2.3 2 1 0 2 2 2 1 Subunit 17 of Mediator complex COG2 PF06148.11 OQR81759.1 - 1e-19 71.0 1.3 1e-19 71.0 1.3 2.0 2 0 0 2 2 2 1 COG (conserved oligomeric Golgi) complex component, COG2 Vps51 PF08700.11 OQR81759.1 - 0.017 15.2 0.0 0.042 13.9 0.0 1.7 1 0 0 1 1 1 0 Vps51/Vps67 DUF2205 PF10224.9 OQR81759.1 - 1.4 9.0 7.1 0.15 12.0 1.3 2.4 2 0 0 2 2 2 0 Short coiled-coil protein Dicty_CAR PF05462.11 OQR81760.1 - 6.1e-08 32.1 13.6 1e-07 31.4 13.6 1.3 1 0 0 1 1 1 1 Slime mold cyclic AMP receptor Exo_endo_phos PF03372.23 OQR81760.1 - 5.7e-07 29.3 0.0 1.5e-06 27.9 0.0 1.8 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family GPR_Gpa2_C PF11970.8 OQR81760.1 - 0.00025 21.0 0.0 0.001 19.1 0.0 2.0 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 C-term 7tm_1 PF00001.21 OQR81760.1 - 0.014 14.7 8.8 0.023 14.0 8.8 1.3 1 0 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) Tetraspanin PF00335.20 OQR81760.1 - 0.067 12.9 10.2 0.29 10.8 0.8 2.6 2 0 0 2 2 2 0 Tetraspanin family Git3 PF11710.8 OQR81760.1 - 3.3 7.4 13.5 15 5.2 13.5 2.1 1 1 0 1 1 1 0 G protein-coupled glucose receptor regulating Gpa2 Glyco_hydro_16 PF00722.21 OQR81761.1 - 2.5e-75 251.8 1.7 9.8e-37 126.1 0.1 2.1 2 0 0 2 2 2 2 Glycosyl hydrolases family 16 SKN1 PF03935.15 OQR81761.1 - 1.5e-38 132.5 9.7 3.8e-11 42.1 0.5 4.0 3 1 1 4 4 4 4 Beta-glucan synthesis-associated protein (SKN1) LBP_BPI_CETP PF01273.25 OQR81761.1 - 0.018 14.6 0.0 0.52 9.9 0.0 2.2 2 0 0 2 2 2 0 LBP / BPI / CETP family, N-terminal domain DUF2401 PF10287.9 OQR81761.1 - 0.023 14.3 0.5 1.5 8.3 0.1 2.4 2 0 0 2 2 2 0 Putative TOS1-like glycosyl hydrolase (DUF2401) MG3 PF17791.1 OQR81761.1 - 0.094 13.0 0.7 17 5.8 0.0 2.7 2 0 0 2 2 2 0 Macroglobulin domain MG3 PIP5K PF01504.18 OQR81763.1 - 2.8e-44 151.4 0.2 5.3e-42 143.9 0.2 2.3 1 1 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase Cpn60_TCP1 PF00118.24 OQR81763.1 - 1.6e-21 76.6 0.1 2.6e-21 75.8 0.1 1.2 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family FYVE PF01363.21 OQR81763.1 - 7.5e-20 70.8 9.4 7.5e-20 70.8 9.4 2.5 2 0 0 2 2 2 1 FYVE zinc finger FYVE_2 PF02318.16 OQR81763.1 - 0.24 11.6 7.3 2.4 8.4 6.5 2.5 2 0 0 2 2 2 0 FYVE-type zinc finger DUF2959 PF11172.8 OQR81767.1 - 0.0013 19.0 0.5 0.0013 19.0 0.5 3.2 1 1 1 3 3 3 1 Protein of unknown function (DUF2959) NPV_P10 PF05531.12 OQR81767.1 - 0.7 10.4 11.9 0.25 11.9 0.7 4.3 5 0 0 5 5 5 0 Nucleopolyhedrovirus P10 protein PGAP1 PF07819.13 OQR81767.1 - 1.5 8.5 5.2 2.7 7.7 0.0 3.1 2 1 3 5 5 5 0 PGAP1-like protein DUF4407 PF14362.6 OQR81767.1 - 5.6 6.2 14.1 0.27 10.5 5.8 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) ABC_tran_CTD PF16326.5 OQR81767.1 - 7.7 6.9 19.3 8.3 6.7 0.1 5.3 3 2 0 5 5 5 0 ABC transporter C-terminal domain HlyIII PF03006.20 OQR81768.1 - 3.1e-59 200.4 29.0 8.8e-52 176.0 21.1 2.1 2 0 0 2 2 2 2 Haemolysin-III related FixP_N PF14715.6 OQR81768.1 - 0.04 13.7 2.8 0.13 12.0 0.0 3.1 2 0 0 2 2 2 0 N-terminal domain of cytochrome oxidase-cbb3, FixP DUF2633 PF11119.8 OQR81768.1 - 5.9 6.9 6.6 1.4 8.9 2.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2633) Abhydrolase_1 PF00561.20 OQR81769.1 - 4.4e-08 33.1 0.1 2.4e-07 30.7 0.0 2.1 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_4 PF08386.10 OQR81769.1 - 3.2e-05 24.0 0.0 0.0001 22.4 0.0 1.9 1 0 0 1 1 1 1 TAP-like protein Hydrolase_4 PF12146.8 OQR81769.1 - 0.00019 20.8 0.0 0.087 12.1 0.0 2.7 3 0 0 3 3 3 2 Serine aminopeptidase, S33 GILT PF03227.16 OQR81770.1 - 1.5e-20 73.4 1.3 3.5e-13 49.7 0.0 2.4 2 0 0 2 2 2 2 Gamma interferon inducible lysosomal thiol reductase (GILT) ScsC_N PF18312.1 OQR81771.1 - 0.1 12.4 0.0 0.65 9.9 0.0 2.1 2 0 0 2 2 2 0 Copper resistance protein ScsC N-terminal domain PAN_4 PF14295.6 OQR81772.1 - 1.3e-05 25.0 7.3 0.00014 21.7 0.3 4.2 5 1 0 5 5 5 2 PAN domain Lustrin_cystein PF14625.6 OQR81772.1 - 0.055 13.9 4.0 0.33 11.4 4.0 2.5 1 0 0 1 1 1 0 Lustrin, cysteine-rich repeated domain Dickkopf_N PF04706.12 OQR81772.1 - 0.057 13.9 1.9 0.057 13.9 1.9 3.4 3 0 0 3 3 3 0 Dickkopf N-terminal cysteine-rich region Ketoacyl-synt_C PF02801.22 OQR81773.1 - 1.1e-38 131.9 0.2 2e-38 131.0 0.2 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain ketoacyl-synt PF00109.26 OQR81773.1 - 1.3e-27 97.0 0.8 1.3e-27 97.0 0.8 1.7 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Thiolase_N PF00108.23 OQR81773.1 - 0.00015 21.3 0.1 0.00041 19.8 0.1 1.6 2 0 0 2 2 2 1 Thiolase, N-terminal domain PAN_1 PF00024.26 OQR81774.1 - 3.6e-09 36.5 7.5 9.6e-06 25.5 1.9 3.6 3 1 1 4 4 4 2 PAN domain PAN_4 PF14295.6 OQR81774.1 - 7.4e-08 32.2 1.9 7.4e-08 32.2 1.9 4.7 5 0 0 5 5 5 2 PAN domain Nodulin_late PF07127.11 OQR81774.1 - 0.08 13.3 0.3 0.08 13.3 0.3 2.9 2 0 0 2 2 2 0 Late nodulin protein SPRY PF00622.28 OQR81775.1 - 0.00016 21.8 0.0 0.00019 21.5 0.0 1.3 1 1 0 1 1 1 1 SPRY domain PAN_1 PF00024.26 OQR81776.1 - 6.4e-09 35.7 7.6 4.2e-06 26.6 0.6 2.6 2 1 1 3 3 3 2 PAN domain PAN_4 PF14295.6 OQR81776.1 - 1e-07 31.7 17.4 0.0002 21.2 0.2 3.4 3 0 0 3 3 3 2 PAN domain PAN_2 PF08276.11 OQR81776.1 - 0.16 12.1 6.4 3.2 7.9 0.6 3.1 3 0 0 3 3 3 0 PAN-like domain MANEC PF07502.14 OQR81776.1 - 0.17 12.1 4.8 4.3 7.7 0.2 3.0 3 0 0 3 3 3 0 MANEC domain NMD3 PF04981.13 OQR81777.1 - 1e-09 38.2 0.0 2.3e-09 37.1 0.0 1.5 2 0 0 2 2 2 1 NMD3 family PQ-loop PF04193.14 OQR81778.1 - 1.4e-08 34.4 4.8 2.4e-08 33.6 4.8 1.4 1 0 0 1 1 1 1 PQ loop repeat MtN3_slv PF03083.16 OQR81778.1 - 0.0097 15.9 1.9 0.023 14.7 1.9 1.7 1 0 0 1 1 1 1 Sugar efflux transporter for intercellular exchange Glyco_hydro_cc PF11790.8 OQR81780.1 - 0.00023 20.8 0.0 0.00035 20.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core DUF3086 PF11285.8 OQR81780.1 - 0.13 11.3 0.0 0.18 10.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3086) Fz PF01392.22 OQR81781.1 - 7.5e-07 29.8 3.0 1.4e-06 28.9 3.0 1.5 1 1 0 1 1 1 1 Fz domain Mid1 PF12929.7 OQR81781.1 - 0.0011 18.3 2.1 0.0011 18.2 2.1 1.2 1 0 0 1 1 1 1 Stretch-activated Ca2+-permeable channel component TCR PF03638.15 OQR81782.1 - 0.005 17.1 18.6 0.005 17.1 18.6 3.5 3 1 0 3 3 3 1 Tesmin/TSO1-like CXC domain, cysteine-rich domain FHA PF00498.26 OQR81785.1 - 7.2e-08 32.7 0.2 3.8e-07 30.4 0.1 2.3 3 0 0 3 3 3 1 FHA domain CHAT PF12770.7 OQR81785.1 - 0.12 11.8 0.0 0.25 10.7 0.0 1.4 1 0 0 1 1 1 0 CHAT domain RasGEF PF00617.19 OQR81786.1 - 5e-31 108.3 1.5 1.4e-30 106.8 0.9 2.0 2 0 0 2 2 2 1 RasGEF domain Ank_4 PF13637.6 OQR81786.1 - 4.5e-17 62.2 4.2 1.2e-06 28.9 0.4 5.9 4 1 1 5 5 5 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 OQR81786.1 - 7.2e-17 61.7 1.3 1.4e-05 25.6 0.0 5.0 2 1 2 4 4 4 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OQR81786.1 - 9.1e-17 60.9 3.1 0.00027 21.2 0.0 6.3 4 1 2 6 6 6 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQR81786.1 - 4.4e-15 54.3 3.5 0.004 17.5 0.0 6.8 6 0 0 6 6 6 4 Ankyrin repeat PH PF00169.29 OQR81786.1 - 1.6e-11 44.6 1.2 8.3e-11 42.3 1.7 2.0 2 0 0 2 2 2 1 PH domain Ank PF00023.30 OQR81786.1 - 1.3e-09 38.0 13.8 0.016 15.7 0.0 6.7 8 0 0 8 8 6 2 Ankyrin repeat PH_8 PF15409.6 OQR81786.1 - 0.00016 21.9 1.5 0.00036 20.8 1.5 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain PH_11 PF15413.6 OQR81786.1 - 0.0015 18.9 7.0 0.01 16.3 7.0 2.3 1 1 0 1 1 1 1 Pleckstrin homology domain PH_3 PF14593.6 OQR81786.1 - 0.034 14.3 0.2 0.073 13.2 0.2 1.5 1 0 0 1 1 1 0 PH domain VPS9 PF02204.18 OQR81786.1 - 0.11 12.8 0.1 0.3 11.3 0.1 1.9 1 0 0 1 1 1 0 Vacuolar sorting protein 9 (VPS9) domain zf-UBR PF02207.20 OQR81787.1 - 3.7e-19 68.7 18.4 3.7e-19 68.7 18.4 3.0 2 0 0 2 2 2 1 Putative zinc finger in N-recognin (UBR box) ClpS PF02617.17 OQR81787.1 - 6.4e-07 29.1 0.1 2.2e-06 27.3 0.1 1.9 1 0 0 1 1 1 1 ATP-dependent Clp protease adaptor protein ClpS Cutinase PF01083.22 OQR81790.1 - 1.6e-37 129.2 3.8 2e-35 122.3 3.8 2.1 1 1 0 1 1 1 1 Cutinase Lipase_3 PF01764.25 OQR81790.1 - 0.01 15.7 0.0 0.13 12.1 0.0 2.2 1 1 0 1 1 1 0 Lipase (class 3) VirJ PF06057.11 OQR81790.1 - 0.033 14.1 0.0 0.042 13.7 0.0 1.2 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) DUF3385 PF11865.8 OQR81791.1 - 0.25 11.3 3.7 0.6 10.0 0.1 3.2 3 1 0 3 3 3 0 Domain of unknown function (DUF3385) Ank_2 PF12796.7 OQR81793.1 - 6.2e-46 154.9 0.1 2.3e-16 60.1 0.1 3.3 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OQR81793.1 - 1.7e-26 89.3 0.3 8.6e-06 25.7 0.0 5.5 5 0 0 5 5 5 4 Ankyrin repeat Ank PF00023.30 OQR81793.1 - 7.2e-25 86.3 3.2 0.00012 22.3 0.0 5.6 5 0 0 5 5 5 5 Ankyrin repeat Ank_4 PF13637.6 OQR81793.1 - 9.4e-22 77.1 2.8 1.9e-09 37.9 0.1 4.5 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 OQR81793.1 - 4.9e-20 71.3 0.8 0.0001 22.5 0.0 5.2 3 2 2 5 5 5 4 Ankyrin repeats (many copies) U-box PF04564.15 OQR81793.1 - 1.1e-15 57.6 0.0 2.6e-15 56.3 0.0 1.6 1 0 0 1 1 1 1 U-box domain zf-Nse PF11789.8 OQR81793.1 - 3.5e-06 26.7 0.0 8.1e-06 25.6 0.0 1.6 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit Ion_trans PF00520.31 OQR81794.1 - 1e-15 57.6 15.1 1.5e-15 57.1 15.1 1.2 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 OQR81794.1 - 4.6e-13 48.9 7.1 1.2e-12 47.6 7.1 1.7 1 0 0 1 1 1 1 Ion channel Aa_trans PF01490.18 OQR81795.1 - 2.4e-16 59.4 20.3 2.4e-16 59.4 20.3 2.5 2 1 1 3 3 3 2 Transmembrane amino acid transporter protein Ribosomal_S27e PF01667.17 OQR81796.1 - 0.02 14.6 16.7 0.75 9.6 4.6 3.7 3 0 0 3 3 3 0 Ribosomal protein S27 YyzF PF14116.6 OQR81796.1 - 0.11 12.6 2.5 3.4 7.8 0.1 3.6 3 0 0 3 3 3 0 YyzF-like protein DUF1084 PF06454.11 OQR81797.1 - 3.4e-09 36.5 9.5 1.3e-08 34.6 9.5 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF1084) HSF_DNA-bind PF00447.17 OQR81798.1 - 3.6e-12 46.7 0.1 5.9e-12 46.0 0.1 1.4 1 0 0 1 1 1 1 HSF-type DNA-binding TCL1_MTCP1 PF01840.17 OQR81798.1 - 0.14 11.8 0.1 0.24 11.1 0.1 1.4 1 1 0 1 1 1 0 TCL1/MTCP1 family DLH PF01738.18 OQR81799.1 - 4.7e-24 85.2 0.0 8.9e-24 84.3 0.0 1.5 1 0 0 1 1 1 1 Dienelactone hydrolase family BK_channel_a PF03493.18 OQR81799.1 - 6.9e-23 80.7 0.0 1.9e-22 79.3 0.0 1.7 1 0 0 1 1 1 1 Calcium-activated BK potassium channel alpha subunit Ion_trans_2 PF07885.16 OQR81799.1 - 1.9e-10 40.6 14.3 2.5e-09 37.0 14.3 2.7 1 1 0 1 1 1 1 Ion channel Peptidase_S15 PF02129.18 OQR81799.1 - 1.5e-06 28.0 0.3 5.9e-06 26.1 0.3 1.9 1 1 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) TrkA_N PF02254.18 OQR81799.1 - 0.0002 21.6 0.2 0.19 12.0 0.0 3.1 3 0 0 3 3 3 2 TrkA-N domain Ion_trans PF00520.31 OQR81799.1 - 0.0021 17.3 17.6 0.0067 15.7 17.6 1.8 1 1 0 1 1 1 1 Ion transport protein Lig_chan PF00060.26 OQR81799.1 - 0.0086 15.9 0.3 0.0086 15.9 0.3 2.0 2 0 0 2 2 2 1 Ligand-gated ion channel SET PF00856.28 OQR81801.1 - 3.4e-23 82.9 0.3 9e-10 39.2 0.1 3.6 2 2 1 3 3 3 3 SET domain SAF PF08666.12 OQR81801.1 - 0.0036 17.9 0.0 11 6.8 0.0 3.4 3 0 0 3 3 3 2 SAF domain Peptidase_M73 PF12389.8 OQR81801.1 - 0.097 12.5 0.0 0.24 11.2 0.0 1.6 2 0 0 2 2 2 0 Camelysin metallo-endopeptidase Cu-oxidase_3 PF07732.15 OQR81801.1 - 0.23 11.5 0.9 15 5.6 0.2 3.1 3 1 0 3 3 3 0 Multicopper oxidase Pkinase PF00069.25 OQR81802.1 - 2.4e-54 184.5 0.0 3.1e-54 184.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQR81802.1 - 1.4e-30 106.5 0.1 5.1e-30 104.6 0.1 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OQR81802.1 - 9.6e-06 24.6 0.0 1.8e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 OQR81802.1 - 8e-05 22.1 0.2 0.00012 21.5 0.2 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 OQR81802.1 - 0.00022 20.7 0.0 0.00054 19.4 0.0 1.5 1 1 0 1 1 1 1 Kinase-like APH PF01636.23 OQR81802.1 - 0.0017 18.3 0.0 0.18 11.7 0.0 2.4 1 1 1 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 OQR81802.1 - 0.014 15.0 0.1 0.25 10.9 0.1 2.1 1 1 1 2 2 2 0 Choline/ethanolamine kinase MuF_C PF18819.1 OQR81802.1 - 0.12 12.4 0.1 11 6.0 0.0 2.4 2 0 0 2 2 2 0 Phage MuF-C-terminal domain CPSase_L_D2 PF02786.17 OQR81803.1 - 4.2e-104 346.6 0.1 5.9e-80 267.7 0.1 2.4 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain Pkinase PF00069.25 OQR81803.1 - 3e-53 180.9 0.0 4.6e-53 180.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain CPSase_sm_chain PF00988.22 OQR81803.1 - 6.6e-49 165.0 0.0 1.4e-48 164.0 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain GATase PF00117.28 OQR81803.1 - 6.1e-46 156.6 0.0 3.7e-45 154.0 0.0 2.3 2 0 0 2 2 2 1 Glutamine amidotransferase class-I CPSase_L_D3 PF02787.19 OQR81803.1 - 2.2e-39 134.6 0.1 4.7e-39 133.5 0.1 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain Pkinase_Tyr PF07714.17 OQR81803.1 - 1.1e-33 116.7 0.0 3e-33 115.2 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase MGS PF02142.22 OQR81803.1 - 1.2e-17 63.8 0.0 2e-16 60.0 0.0 2.9 2 0 0 2 2 2 1 MGS-like domain ATP-grasp PF02222.22 OQR81803.1 - 1.7e-14 53.7 0.1 3e-08 33.4 0.0 2.4 2 0 0 2 2 2 2 ATP-grasp domain ATPgrasp_Ter PF15632.6 OQR81803.1 - 1.7e-13 50.5 0.1 1.4e-05 24.8 0.0 2.4 2 0 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon Dala_Dala_lig_C PF07478.13 OQR81803.1 - 8.1e-09 35.3 0.2 0.00032 20.3 0.0 2.4 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus Peptidase_C26 PF07722.13 OQR81803.1 - 0.00024 20.9 1.3 0.032 14.0 1.3 2.4 1 1 0 1 1 1 1 Peptidase C26 Pkinase_fungal PF17667.1 OQR81803.1 - 0.00037 19.4 0.0 0.00084 18.2 0.0 1.5 1 0 0 1 1 1 1 Fungal protein kinase ATP-grasp_3 PF02655.14 OQR81803.1 - 0.004 17.2 0.4 1.4 9.0 0.0 3.0 3 0 0 3 3 3 1 ATP-grasp domain GARS_A PF01071.19 OQR81803.1 - 0.0045 16.8 0.1 0.17 11.6 0.0 3.0 2 1 0 2 2 2 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain Kinase-like PF14531.6 OQR81803.1 - 0.0046 16.3 0.0 0.0094 15.3 0.0 1.4 1 0 0 1 1 1 1 Kinase-like DJ-1_PfpI PF01965.24 OQR81803.1 - 0.01 15.7 0.1 0.38 10.5 0.1 2.7 3 0 0 3 3 2 0 DJ-1/PfpI family ATP-grasp_5 PF13549.6 OQR81803.1 - 0.011 15.2 0.0 2.7 7.4 0.0 2.4 2 0 0 2 2 2 0 ATP-grasp domain APH PF01636.23 OQR81803.1 - 0.027 14.4 0.1 0.075 12.9 0.2 1.6 2 0 0 2 2 1 0 Phosphotransferase enzyme family DUF603 PF04645.12 OQR81803.1 - 0.11 12.3 0.0 0.26 10.9 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function, DUF603 TrkA_N PF02254.18 OQR81803.1 - 0.12 12.7 0.1 14 6.0 0.1 2.8 2 0 0 2 2 2 0 TrkA-N domain Kdo PF06293.14 OQR81803.1 - 0.2 11.0 0.1 0.43 9.9 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family ABC_membrane PF00664.23 OQR81804.1 - 1.8e-21 77.0 16.5 1.9e-21 76.9 15.6 1.5 1 1 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 OQR81804.1 - 0.076 13.5 0.1 0.17 12.4 0.1 1.5 1 0 0 1 1 1 0 ABC transporter AAA_29 PF13555.6 OQR81804.1 - 0.095 12.5 0.1 0.34 10.7 0.1 1.9 2 0 0 2 2 2 0 P-loop containing region of AAA domain PI-PLC-X PF00388.19 OQR81804.1 - 0.11 12.1 0.0 0.22 11.1 0.0 1.4 1 0 0 1 1 1 0 Phosphatidylinositol-specific phospholipase C, X domain Eno-Rase_NADH_b PF12242.8 OQR81804.1 - 0.15 11.9 0.6 0.35 10.7 0.6 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase HSF_DNA-bind PF00447.17 OQR81805.1 - 4.2e-15 56.1 0.0 9.4e-15 55.0 0.0 1.6 1 0 0 1 1 1 1 HSF-type DNA-binding PX PF00787.24 OQR81807.1 - 1.7e-09 37.7 0.0 3.1e-09 36.8 0.0 1.4 1 0 0 1 1 1 1 PX domain DAO PF01266.24 OQR81808.1 - 5.6e-67 226.8 0.0 6.9e-67 226.5 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 OQR81808.1 - 5e-08 33.1 0.1 1.1e-07 31.9 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 OQR81808.1 - 1.9e-05 24.1 1.4 8.1e-05 22.0 0.2 2.4 3 0 0 3 3 3 1 Thi4 family Pyr_redox_2 PF07992.14 OQR81808.1 - 4.5e-05 22.8 0.6 0.011 15.0 0.9 2.3 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 OQR81808.1 - 8.3e-05 21.8 1.8 9.7e-05 21.6 0.4 1.7 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.14 OQR81808.1 - 0.0003 19.6 0.7 0.0026 16.6 0.8 2.0 2 0 0 2 2 2 1 HI0933-like protein 3HCDH_N PF02737.18 OQR81808.1 - 0.001 19.0 0.1 0.002 18.0 0.1 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_binding_3 PF01494.19 OQR81808.1 - 0.0014 17.9 0.2 0.0023 17.2 0.2 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.27 OQR81808.1 - 0.0032 18.0 0.7 0.09 13.3 0.2 2.8 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase UDPG_MGDP_dh_N PF03721.14 OQR81808.1 - 0.0032 17.0 0.1 0.0051 16.4 0.1 1.3 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_Gly3P_dh_N PF01210.23 OQR81808.1 - 0.0043 17.0 0.0 0.0063 16.5 0.0 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Pyr_redox_3 PF13738.6 OQR81808.1 - 0.0078 15.5 1.7 0.013 14.8 0.9 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase 2-Hacid_dh_C PF02826.19 OQR81808.1 - 0.012 15.0 0.1 0.019 14.3 0.1 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ApbA PF02558.16 OQR81808.1 - 0.019 14.6 0.2 0.037 13.7 0.2 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA FAD_oxidored PF12831.7 OQR81808.1 - 0.034 13.5 0.1 0.043 13.2 0.1 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase NAD_binding_2 PF03446.15 OQR81808.1 - 0.04 14.1 0.1 0.073 13.2 0.1 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 OQR81808.1 - 0.042 14.4 0.5 0.098 13.3 0.5 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent IlvN PF07991.12 OQR81808.1 - 0.049 13.2 0.3 0.12 12.0 0.3 1.7 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain AlaDh_PNT_C PF01262.21 OQR81808.1 - 0.052 12.8 0.5 0.098 11.9 0.5 1.4 1 1 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain TrkA_N PF02254.18 OQR81808.1 - 0.11 12.7 1.1 0.39 11.0 0.1 2.0 2 0 0 2 2 2 0 TrkA-N domain XdhC_C PF13478.6 OQR81808.1 - 0.12 12.9 0.0 0.18 12.3 0.0 1.4 1 0 0 1 1 1 0 XdhC Rossmann domain ThiF PF00899.21 OQR81808.1 - 0.13 11.6 0.2 0.22 10.9 0.2 1.3 1 0 0 1 1 1 0 ThiF family Amino_oxidase PF01593.24 OQR81808.1 - 0.13 11.5 0.0 0.2 10.9 0.0 1.3 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase NAD_binding_7 PF13241.6 OQR81808.1 - 0.14 12.6 0.4 0.43 11.0 0.4 2.0 1 1 0 1 1 1 0 Putative NAD(P)-binding Lycopene_cycl PF05834.12 OQR81808.1 - 0.21 10.6 0.8 0.34 9.9 0.8 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein RabGAP-TBC PF00566.18 OQR81810.1 - 1.3e-40 139.3 0.0 2.4e-40 138.5 0.0 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain PriA_C PF18074.1 OQR81810.1 - 0.095 13.5 0.0 0.27 12.1 0.0 1.7 1 0 0 1 1 1 0 Primosomal protein N C-terminal domain Radial_spoke_3 PF06098.11 OQR81811.1 - 1.2e-96 323.4 14.4 1.4e-96 323.1 14.4 1.1 1 0 0 1 1 1 1 Radial spoke protein 3 MIP PF00230.20 OQR81811.1 - 1.8e-50 171.8 5.1 2.4e-50 171.3 5.1 1.2 1 0 0 1 1 1 1 Major intrinsic protein AAA_32 PF13654.6 OQR81811.1 - 0.00043 19.2 5.9 0.0006 18.7 5.9 1.3 1 0 0 1 1 1 1 AAA domain DUF1418 PF07214.12 OQR81811.1 - 0.17 11.8 0.3 0.43 10.5 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1418) SET PF00856.28 OQR81812.1 - 9e-06 26.2 0.0 2.7e-05 24.6 0.0 1.8 1 1 0 1 1 1 1 SET domain LicD PF04991.13 OQR81813.1 - 0.0026 17.9 0.2 0.012 15.8 0.2 2.0 2 0 0 2 2 2 1 LicD family zf-RanBP PF00641.18 OQR81814.1 - 4.8e-06 25.8 3.1 4.8e-06 25.8 3.1 1.9 2 0 0 2 2 2 1 Zn-finger in Ran binding protein and others Exo_endo_phos PF03372.23 OQR81814.1 - 0.0043 16.6 0.1 0.013 15.0 0.1 1.9 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DUF3213 PF11491.8 OQR81814.1 - 0.0096 16.1 1.4 0.41 10.9 0.3 2.8 2 1 1 3 3 3 1 Protein of unknown function (DUF3213) DZR PF12773.7 OQR81814.1 - 0.082 12.9 1.5 0.18 11.8 1.5 1.5 1 0 0 1 1 1 0 Double zinc ribbon ATP-synt_E PF05680.12 OQR81814.1 - 0.091 13.1 4.7 0.15 12.4 4.7 1.3 1 0 0 1 1 1 0 ATP synthase E chain DUF3090 PF11290.8 OQR81814.1 - 0.13 12.1 1.6 0.68 9.7 0.6 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3090) Lactamase_B_2 PF12706.7 OQR81815.1 - 7e-10 38.7 0.0 1.2e-05 24.9 0.0 2.7 2 1 0 2 2 2 2 Beta-lactamase superfamily domain Lactamase_B PF00753.27 OQR81815.1 - 6.3e-06 26.3 0.1 1.6e-05 25.0 0.1 1.6 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_4 PF13691.6 OQR81815.1 - 7.5e-05 22.3 0.0 0.00015 21.3 0.0 1.6 1 0 0 1 1 1 1 tRNase Z endonuclease HTH_Tnp_Tc5 PF03221.16 OQR81816.1 - 2.1e-12 46.8 0.4 7.2e-12 45.2 0.2 2.1 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain DDE_1 PF03184.19 OQR81816.1 - 3.9e-06 26.6 0.1 1e-05 25.3 0.1 1.8 1 0 0 1 1 1 1 DDE superfamily endonuclease Me-amine-dh_H PF06433.11 OQR81816.1 - 0.12 11.2 0.1 0.23 10.3 0.1 1.3 1 0 0 1 1 1 0 Methylamine dehydrogenase heavy chain (MADH) GH-E PF14410.6 OQR81816.1 - 0.15 12.5 0.3 6.2 7.3 0.1 2.9 2 0 0 2 2 2 0 HNH/ENDO VII superfamily nuclease with conserved GHE residues Arm PF00514.23 OQR81817.1 - 0.0033 17.4 4.1 0.045 13.8 0.1 3.3 3 0 0 3 3 3 1 Armadillo/beta-catenin-like repeat C1_1 PF00130.22 OQR81817.1 - 0.006 16.4 1.8 0.006 16.4 1.8 2.4 2 0 0 2 2 2 1 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-HC5HC2H PF13771.6 OQR81817.1 - 0.0063 16.7 8.8 0.0063 16.7 8.8 2.9 2 2 1 3 3 3 1 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.6 OQR81817.1 - 0.018 15.2 9.6 0.018 15.2 9.6 2.7 2 0 0 2 2 2 0 PHD-zinc-finger like domain PHD PF00628.29 OQR81817.1 - 0.019 14.9 9.6 0.075 12.9 9.6 2.1 1 0 0 1 1 1 0 PHD-finger zf-RING-like PF08746.11 OQR81817.1 - 0.15 12.4 9.6 0.063 13.6 4.2 2.9 2 0 0 2 2 2 0 RING-like domain DUF659 PF04937.15 OQR81819.1 - 9.7e-21 74.2 0.0 2.1e-20 73.2 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 OQR81819.1 - 1.2e-06 28.2 0.3 5.4e-06 26.1 0.0 2.3 2 1 0 2 2 2 1 hAT family C-terminal dimerisation region RRM_1 PF00076.22 OQR81820.1 - 4.4e-27 93.7 6.1 1.6e-15 56.6 0.2 2.7 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 OQR81820.1 - 1.1e-05 25.1 0.1 0.035 13.9 0.0 2.6 2 1 0 2 2 2 2 Occluded RNA-recognition motif Nup35_RRM_2 PF14605.6 OQR81820.1 - 0.00099 19.1 0.0 1.3 9.0 0.0 2.5 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif RRM_5 PF13893.6 OQR81820.1 - 0.001 18.7 0.1 0.54 9.9 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 OQR81820.1 - 0.17 12.1 0.1 2.3 8.4 0.1 2.7 2 2 1 3 3 3 0 RNA recognition motif CDC45 PF02724.14 OQR81820.1 - 7.3 4.7 10.3 8.1 4.6 10.3 1.2 1 0 0 1 1 1 0 CDC45-like protein NMD3 PF04981.13 OQR81821.1 - 2.1e-69 233.7 2.4 2.1e-69 233.7 2.4 1.6 2 0 0 2 2 2 1 NMD3 family DZR PF12773.7 OQR81821.1 - 3.8 7.6 6.5 97 3.1 3.9 3.1 3 0 0 3 3 3 0 Double zinc ribbon Enolase_C PF00113.22 OQR81822.1 - 1.1e-37 129.9 0.0 2e-37 129.0 0.0 1.4 1 1 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.16 OQR81822.1 - 4.4e-16 59.3 0.0 7.9e-16 58.4 0.0 1.5 1 0 0 1 1 1 1 Enolase, N-terminal domain Dpy-30 PF05186.13 OQR81822.1 - 0.15 11.8 0.0 0.44 10.3 0.0 1.8 1 0 0 1 1 1 0 Dpy-30 motif Pkinase PF00069.25 OQR81823.1 - 2.9e-80 269.4 0.0 4.2e-80 268.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQR81823.1 - 3.3e-38 131.4 0.0 5.3e-38 130.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OQR81823.1 - 9.8e-07 28.4 0.0 4.1e-06 26.3 0.0 1.8 1 1 1 2 2 2 1 Kinase-like RIO1 PF01163.22 OQR81823.1 - 2.7e-05 23.9 0.4 4.9e-05 23.0 0.4 1.3 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 OQR81823.1 - 0.00024 21.1 0.0 0.2 11.5 0.0 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family FTA2 PF13095.6 OQR81823.1 - 0.00077 19.2 0.1 0.21 11.2 0.0 2.4 1 1 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Haspin_kinase PF12330.8 OQR81823.1 - 0.0024 16.9 0.1 0.0043 16.0 0.1 1.4 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 OQR81823.1 - 0.0044 16.4 0.2 0.01 15.2 0.2 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.11 OQR81823.1 - 0.0087 15.2 0.0 0.014 14.5 0.0 1.2 1 0 0 1 1 1 1 Seadornavirus VP7 PRCC PF10253.9 OQR81824.1 - 5.6e-10 40.4 0.4 6.9e-10 40.1 0.4 1.2 1 0 0 1 1 1 1 Mitotic checkpoint regulator, MAD2B-interacting Ank_2 PF12796.7 OQR81825.1 - 7e-31 106.7 2.5 1.3e-16 60.9 0.2 4.1 3 1 1 4 4 4 3 Ankyrin repeats (3 copies) Ank PF00023.30 OQR81825.1 - 3.4e-21 74.7 5.5 2.4e-06 27.7 0.1 5.2 6 0 0 6 6 6 4 Ankyrin repeat Ank_3 PF13606.6 OQR81825.1 - 8.1e-19 65.8 0.1 0.0024 18.2 0.0 5.3 7 0 0 7 7 7 4 Ankyrin repeat Ank_4 PF13637.6 OQR81825.1 - 2.5e-17 63.0 0.2 3.7e-08 33.8 0.0 4.2 4 1 0 4 4 4 3 Ankyrin repeats (many copies) Imm_superinfect PF14373.6 OQR81825.1 - 4e-07 29.8 0.3 4.1 7.4 0.0 5.1 5 0 0 5 5 5 3 Superinfection immunity protein Ank_5 PF13857.6 OQR81825.1 - 1e-05 25.7 0.7 0.035 14.4 0.1 4.7 3 1 2 5 5 5 2 Ankyrin repeats (many copies) STT3_PglB_C PF18527.1 OQR81825.1 - 0.017 15.2 3.3 2 8.6 0.1 3.9 5 0 0 5 5 5 0 STT3/PglB C-terminal beta-barrel domain HP0268 PF18618.1 OQR81825.1 - 0.033 14.6 0.0 3.5 8.1 0.0 2.8 2 1 0 2 2 2 0 HP0268 BRCT_2 PF16589.5 OQR81825.1 - 0.05 14.0 1.5 9.1 6.8 1.5 3.2 1 1 0 1 1 1 0 BRCT domain, a BRCA1 C-terminus domain Adap_comp_sub PF00928.21 OQR81826.1 - 7.8e-91 304.1 0.1 1.2e-90 303.5 0.1 1.3 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 OQR81826.1 - 8.9e-07 28.9 1.6 8.9e-07 28.9 1.6 2.1 3 0 0 3 3 3 1 Clathrin adaptor complex small chain Myb_DNA-binding PF00249.31 OQR81826.1 - 0.00016 21.8 0.0 0.0035 17.5 0.0 2.6 2 0 0 2 2 2 1 Myb-like DNA-binding domain Retrotran_gag_2 PF14223.6 OQR81826.1 - 0.0016 18.1 1.0 0.0038 16.9 1.0 1.6 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type Longin PF13774.6 OQR81826.1 - 0.044 13.8 0.5 0.26 11.4 0.1 2.4 2 0 0 2 2 2 0 Regulated-SNARE-like domain DAO PF01266.24 OQR81828.1 - 1.6e-25 90.5 0.0 3e-25 89.6 0.0 1.4 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 OQR81828.1 - 0.0053 15.9 0.0 0.072 12.2 0.3 2.4 3 0 0 3 3 3 1 FAD binding domain GIDA PF01134.22 OQR81828.1 - 0.011 14.8 4.5 0.11 11.6 0.3 2.6 3 0 0 3 3 3 0 Glucose inhibited division protein A Pyr_redox_2 PF07992.14 OQR81828.1 - 0.013 14.8 0.0 0.024 13.9 0.0 1.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 OQR81828.1 - 0.051 12.9 0.4 0.099 11.9 0.4 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_8 PF13450.6 OQR81828.1 - 0.19 12.0 0.6 0.5 10.6 0.2 1.9 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 OQR81828.1 - 0.2 10.9 0.1 0.37 10.0 0.1 1.3 1 0 0 1 1 1 0 Thi4 family RdRP PF05183.12 OQR81829.1 - 1.2e-84 285.0 0.0 6.9e-72 242.9 0.0 2.1 2 0 0 2 2 2 2 RNA dependent RNA polymerase Glyco_hydro_3 PF00933.21 OQR81830.1 - 3e-48 164.8 0.0 4.3e-48 164.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.22 OQR81830.1 - 1.2e-36 126.6 0.0 2e-36 125.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Ricin_B_lectin PF00652.22 OQR81830.1 - 6.2e-27 94.4 12.0 1.8e-13 50.8 2.3 2.7 2 0 0 2 2 2 2 Ricin-type beta-trefoil lectin domain Fn3-like PF14310.6 OQR81830.1 - 9.5e-09 35.3 0.0 2.3e-08 34.0 0.0 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain RicinB_lectin_2 PF14200.6 OQR81830.1 - 6.3e-08 33.2 16.9 0.0039 17.9 0.9 3.9 2 1 0 3 3 3 3 Ricin-type beta-trefoil lectin domain-like CDtoxinA PF03498.14 OQR81830.1 - 8.2e-05 22.2 2.0 0.098 12.2 0.9 2.4 2 0 0 2 2 2 2 Cytolethal distending toxin A/C domain CARDB PF07705.11 OQR81830.1 - 0.026 14.8 0.4 0.093 13.0 0.4 1.9 1 0 0 1 1 1 0 CARDB Phage_spike PF18715.1 OQR81830.1 - 0.09 12.9 3.1 0.2 11.8 1.8 2.2 2 0 0 2 2 2 0 Phage spike trimer DUF11 PF01345.18 OQR81830.1 - 0.29 11.5 2.6 2.9 8.3 2.6 2.6 1 1 0 1 1 1 0 Domain of unknown function DUF11 NDUF_B12 PF08122.12 OQR81831.1 - 5e-07 29.7 0.0 8.8e-07 28.9 0.0 1.4 1 1 0 1 1 1 1 NADH-ubiquinone oxidoreductase B12 subunit family Peroxin-3 PF04882.12 OQR81832.1 - 3.1e-22 79.2 3.2 1.5e-09 37.4 0.1 3.2 1 1 1 3 3 3 3 Peroxin-3 ACDC PF14733.6 OQR81832.1 - 0.23 11.8 2.6 16 5.9 1.6 3.3 2 1 0 2 2 2 0 AP2-coincident C-terminal tRNA-synt_2d PF01409.20 OQR81833.1 - 1.1e-84 283.8 0.1 1.6e-84 283.2 0.1 1.2 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) PheRS_DBD3 PF18553.1 OQR81833.1 - 9.4e-20 70.7 0.1 2.3e-19 69.4 0.1 1.7 1 0 0 1 1 1 1 PheRS DNA binding domain 3 PheRS_DBD1 PF18552.1 OQR81833.1 - 4.8e-10 39.1 0.1 1.2e-09 37.7 0.1 1.7 1 0 0 1 1 1 1 PheRS DNA binding domain 1 tRNA_synthFbeta PF17759.1 OQR81833.1 - 3.1e-09 36.6 0.0 0.0002 20.9 0.0 2.2 2 0 0 2 2 2 2 Phenylalanyl tRNA synthetase beta chain CLM domain tRNA-synt_2 PF00152.20 OQR81833.1 - 3.4e-05 23.1 0.1 0.00011 21.4 0.0 1.8 2 0 0 2 2 2 1 tRNA synthetases class II (D, K and N) tRNA-synt_2b PF00587.25 OQR81833.1 - 0.0028 17.6 0.0 0.0059 16.6 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) RL PF17797.1 OQR81833.1 - 0.064 13.2 0.1 0.27 11.2 0.0 2.0 2 0 0 2 2 2 0 RL domain DUF3130 PF11328.8 OQR81833.1 - 0.093 13.0 0.1 0.2 11.9 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3130 HTH_30 PF13556.6 OQR81833.1 - 0.16 11.8 0.2 0.67 9.8 0.0 2.1 3 0 0 3 3 3 0 PucR C-terminal helix-turn-helix domain Ank_5 PF13857.6 OQR81834.1 - 5.7e-17 61.6 0.9 0.0074 16.6 0.0 5.7 3 2 2 5 5 5 5 Ankyrin repeats (many copies) Ank_2 PF12796.7 OQR81834.1 - 5.1e-15 55.8 0.1 0.00019 21.9 0.0 4.0 3 1 1 4 4 4 3 Ankyrin repeats (3 copies) FYVE PF01363.21 OQR81834.1 - 1.6e-11 44.1 12.4 2.8e-11 43.4 12.4 1.4 1 0 0 1 1 1 1 FYVE zinc finger Ank_3 PF13606.6 OQR81834.1 - 2.2e-10 39.8 4.8 0.57 10.9 0.0 7.3 8 0 0 8 8 8 2 Ankyrin repeat Ank_4 PF13637.6 OQR81834.1 - 7.5e-10 39.2 4.0 0.00064 20.2 0.1 5.1 4 2 2 6 6 6 3 Ankyrin repeats (many copies) Ank PF00023.30 OQR81834.1 - 8.1e-07 29.2 7.5 3.2 8.3 0.0 7.2 8 0 0 8 8 8 1 Ankyrin repeat HAUS-augmin3 PF14932.6 OQR81834.1 - 0.0056 16.3 1.2 0.0094 15.6 1.2 1.3 1 0 0 1 1 1 1 HAUS augmin-like complex subunit 3 Cytochrom_CIII PF02085.16 OQR81834.1 - 0.019 15.3 6.6 0.035 14.4 6.6 1.3 1 0 0 1 1 1 0 Class III cytochrome C family DUF4686 PF15742.5 OQR81834.1 - 0.023 13.9 4.3 0.039 13.1 4.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4686) DUF2046 PF09755.9 OQR81834.1 - 0.024 13.8 1.2 0.065 12.4 0.6 1.9 2 0 0 2 2 2 0 Uncharacterized conserved protein H4 (DUF2046) FYVE_2 PF02318.16 OQR81834.1 - 0.58 10.4 4.5 1.5 9.0 4.5 1.7 1 0 0 1 1 1 0 FYVE-type zinc finger LRR_4 PF12799.7 OQR81835.1 - 0.0049 17.3 7.0 0.095 13.2 1.1 2.6 1 1 3 4 4 4 4 Leucine Rich repeats (2 copies) DDHD PF02862.17 OQR81836.1 - 3.9e-26 92.6 1.2 2.8e-21 76.7 0.2 4.6 2 2 1 3 3 3 2 DDHD domain PH PF00169.29 OQR81836.1 - 4.9e-07 30.2 3.6 0.026 15.0 0.1 3.5 3 0 0 3 3 3 2 PH domain SDA1 PF05285.12 OQR81836.1 - 0.02 14.4 26.9 0.03 13.7 26.9 1.2 1 0 0 1 1 1 0 SDA1 eIF3_p135 PF12807.7 OQR81836.1 - 2.3 8.2 9.1 0.74 9.8 4.6 2.3 1 1 1 2 2 2 0 Translation initiation factor eIF3 subunit 135 MORN PF02493.20 OQR81837.1 - 0.00019 21.1 8.0 0.031 14.2 0.3 3.1 3 0 0 3 3 3 2 MORN repeat CCDC-167 PF15188.6 OQR81837.1 - 0.071 13.5 7.8 0.035 14.4 5.1 1.9 1 1 1 2 2 2 0 Coiled-coil domain-containing protein 167 C2 PF00168.30 OQR81838.1 - 1.6e-46 156.8 0.2 6.5e-05 23.2 0.0 10.2 10 0 0 10 10 10 8 C2 domain EF-hand_8 PF13833.6 OQR81838.1 - 1.6e-17 63.1 6.4 4.7e-07 29.5 0.1 4.3 3 1 1 4 4 4 4 EF-hand domain pair EF-hand_7 PF13499.6 OQR81838.1 - 6.8e-17 61.7 5.0 2.7e-06 27.7 0.1 4.5 4 0 0 4 4 4 3 EF-hand domain pair EF-hand_1 PF00036.32 OQR81838.1 - 1.6e-16 58.5 5.5 3.2e-05 23.2 0.1 5.5 5 0 0 5 5 5 3 EF hand EF-hand_6 PF13405.6 OQR81838.1 - 1.6e-14 52.5 3.4 0.0024 17.7 0.0 5.7 5 0 0 5 5 5 3 EF-hand domain SAM_2 PF07647.17 OQR81838.1 - 7e-14 51.7 0.3 2.1e-13 50.2 0.3 1.9 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) EF-hand_5 PF13202.6 OQR81838.1 - 9.4e-13 47.0 0.5 2.9e-05 23.3 0.0 3.9 3 0 0 3 3 3 2 EF hand SAM_1 PF00536.30 OQR81838.1 - 2.2e-12 47.3 0.3 4.9e-12 46.1 0.3 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Sec5 PF15469.6 OQR81839.1 - 6.2e-21 75.1 7.5 1.7e-20 73.6 5.9 2.7 1 1 0 1 1 1 1 Exocyst complex component Sec5 Vps51 PF08700.11 OQR81839.1 - 0.00017 21.6 2.8 0.00079 19.5 1.6 2.9 1 1 1 2 2 2 1 Vps51/Vps67 Dor1 PF04124.12 OQR81839.1 - 0.029 13.1 13.1 0.024 13.3 9.9 2.2 2 0 0 2 2 2 0 Dor1-like family TetR_C_29 PF17938.1 OQR81839.1 - 0.032 14.3 0.3 0.091 12.9 0.3 1.9 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain UPF0181 PF03701.14 OQR81839.1 - 0.4 10.4 2.1 1.1 9.0 0.0 2.5 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0181) COG2 PF06148.11 OQR81839.1 - 1.1 9.4 8.0 0.16 12.1 2.1 2.6 3 0 0 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 PolC_DP2 PF03833.13 OQR81839.1 - 2.1 6.1 6.8 0.098 10.5 0.9 1.6 2 0 0 2 2 2 0 DNA polymerase II large subunit DP2 Peptidase_S46 PF10459.9 OQR81839.1 - 9.8 4.7 10.2 3 6.4 7.4 1.5 2 0 0 2 2 2 0 Peptidase S46 FtsL PF04999.13 OQR81840.1 - 0.32 11.0 4.8 1.5 8.9 4.8 2.1 1 0 0 1 1 1 0 Cell division protein FtsL La PF05383.17 OQR81841.1 - 5.8e-20 71.1 0.4 2.4e-19 69.1 0.4 2.1 2 0 0 2 2 2 1 La domain RRM_3 PF08777.11 OQR81841.1 - 3.4e-19 68.8 0.2 8.8e-14 51.4 0.2 3.7 3 0 0 3 3 3 3 RNA binding motif Ribosomal_L22 PF00237.19 OQR81842.1 - 0.036 14.3 0.0 0.044 14.0 0.0 1.1 1 0 0 1 1 1 0 Ribosomal protein L22p/L17e Pyr_redox_dim PF02852.22 OQR81843.1 - 2.4e-31 108.2 1.1 3.4e-31 107.7 1.1 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox_2 PF07992.14 OQR81843.1 - 2.8e-13 49.8 0.1 5.8e-13 48.7 0.0 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase SUFU PF05076.13 OQR81844.1 - 0.024 14.6 0.5 0.12 12.4 0.2 2.2 2 0 0 2 2 2 0 Suppressor of fused protein (SUFU) TPR_9 PF13371.6 OQR81845.1 - 4.8e-09 36.3 0.2 6.1e-07 29.5 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.28 OQR81845.1 - 6.1e-09 35.3 8.1 0.0032 17.2 1.1 4.6 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_2 PF07719.17 OQR81845.1 - 1.6e-07 30.9 9.3 0.0092 16.0 0.1 3.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 OQR81845.1 - 1.8e-06 28.1 0.9 0.05 13.9 0.0 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_10 PF13374.6 OQR81845.1 - 1.5e-05 24.7 1.3 0.067 13.1 0.0 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.6 OQR81845.1 - 2.3e-05 24.1 0.3 0.16 12.1 0.2 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 OQR81845.1 - 2.3e-05 24.8 1.1 1.1 10.2 0.3 3.4 2 1 1 3 3 3 2 Tetratricopeptide repeat ANAPC3 PF12895.7 OQR81845.1 - 0.00014 22.0 4.0 0.0046 17.2 0.5 2.5 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.6 OQR81845.1 - 0.00032 21.1 2.6 0.6 10.7 0.1 3.2 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 OQR81845.1 - 0.0005 20.1 3.9 1.1 9.7 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 OQR81845.1 - 0.0015 18.5 1.4 1.6 8.9 0.0 2.9 2 1 1 3 3 3 2 Fis1 C-terminal tetratricopeptide repeat TPR_11 PF13414.6 OQR81845.1 - 0.0034 17.0 2.1 0.049 13.3 0.5 2.6 2 0 0 2 2 2 1 TPR repeat TPR_16 PF13432.6 OQR81845.1 - 0.033 14.8 4.1 2.2 9.0 0.8 3.3 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 OQR81845.1 - 0.073 13.7 0.5 1.2e+02 3.7 0.1 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_17 PF13431.6 OQR81845.1 - 0.078 13.4 1.3 1.5 9.4 0.1 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF3224 PF11528.8 OQR81846.1 - 0.0064 16.3 2.1 5.1 6.9 0.1 4.1 2 1 2 4 4 4 1 Protein of unknown function (DUF3224) DUF1939 PF09154.10 OQR81846.1 - 0.02 15.0 0.5 77 3.6 0.0 4.5 3 2 2 5 5 5 0 Domain of unknown function (DUF1939) Vma12 PF11712.8 OQR81850.1 - 4.7e-14 52.6 0.2 6.5e-14 52.2 0.2 1.1 1 0 0 1 1 1 1 Endoplasmic reticulum-based factor for assembly of V-ATPase DUF4407 PF14362.6 OQR81850.1 - 0.001 18.5 1.1 0.001 18.5 1.1 2.0 1 1 1 2 2 2 1 Domain of unknown function (DUF4407) FLYWCH_u PF16662.5 OQR81850.1 - 0.33 11.0 0.2 0.33 11.0 0.2 2.3 2 0 0 2 2 2 0 FLYWCH-type zinc finger-containing protein 1 Aa_trans PF01490.18 OQR81851.1 - 9.2e-44 149.8 27.2 1.4e-43 149.2 27.2 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 OQR81851.1 - 6.7e-05 22.1 13.9 6.7e-05 22.1 13.9 3.0 2 1 0 3 3 3 1 Tryptophan/tyrosine permease family Med4 PF10018.9 OQR81852.1 - 6.6e-19 68.3 0.8 4.8e-18 65.5 0.2 2.5 2 0 0 2 2 2 1 Vitamin-D-receptor interacting Mediator subunit 4 Prominin PF05478.11 OQR81852.1 - 9.5e-09 33.8 0.3 9.5e-09 33.8 0.3 4.6 6 0 0 6 6 6 3 Prominin Sua5_yciO_yrdC PF01300.18 OQR81852.1 - 0.0088 15.6 0.5 0.027 14.0 0.4 1.9 2 0 0 2 2 2 1 Telomere recombination MpPF26 PF07666.11 OQR81852.1 - 0.04 14.0 0.1 0.04 14.0 0.1 3.7 3 1 0 3 3 3 0 M penetrans paralogue family 26 Spo0A_C PF08769.11 OQR81852.1 - 0.046 13.8 0.3 0.22 11.6 0.0 2.3 2 0 0 2 2 2 0 Sporulation initiation factor Spo0A C terminal Muted PF14942.6 OQR81852.1 - 1.5 9.2 13.3 0.84 10.0 2.9 3.5 3 0 0 3 3 3 0 Organelle biogenesis, Muted-like protein ABC_tran_CTD PF16326.5 OQR81852.1 - 3.5 7.9 6.1 4.4 7.6 1.2 2.9 3 0 0 3 3 3 0 ABC transporter C-terminal domain Aa_trans PF01490.18 OQR81853.1 - 2.4e-43 148.4 25.2 3.4e-43 147.9 25.2 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 OQR81853.1 - 0.00011 21.4 17.8 0.00011 21.4 17.8 2.4 2 1 0 2 2 2 1 Tryptophan/tyrosine permease family PrgI PF12666.7 OQR81855.1 - 0.61 10.8 4.1 0.37 11.5 0.8 2.0 1 1 1 2 2 2 0 PrgI family protein ABC1 PF03109.16 OQR81856.1 - 3.7e-30 104.5 0.6 6.6e-30 103.7 0.6 1.4 1 0 0 1 1 1 1 ABC1 family Pkinase PF00069.25 OQR81856.1 - 0.0016 17.8 0.1 0.0038 16.6 0.1 1.5 1 0 0 1 1 1 1 Protein kinase domain RIO1 PF01163.22 OQR81856.1 - 0.041 13.5 0.3 0.14 11.7 0.1 1.9 2 0 0 2 2 2 0 RIO1 family APH PF01636.23 OQR81856.1 - 0.077 12.9 0.1 0.25 11.2 0.1 1.9 1 1 0 1 1 1 0 Phosphotransferase enzyme family Tim44 PF04280.15 OQR81857.1 - 5.4e-29 101.2 0.6 5.4e-29 101.2 0.6 2.8 2 1 1 3 3 3 1 Tim44-like domain DUF883 PF05957.13 OQR81857.1 - 0.01 16.4 11.4 0.16 12.6 9.0 2.7 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) Lant_dehydr_C PF14028.6 OQR81857.1 - 0.22 11.0 4.1 0.12 11.9 2.0 1.6 2 0 0 2 2 2 0 Lantibiotic biosynthesis dehydratase C-term MADF_DNA_bdg PF10545.9 OQR81857.1 - 0.38 11.1 4.8 1.8 8.9 3.6 2.4 2 0 0 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like DUF3810 PF12725.7 OQR81857.1 - 0.67 9.2 4.4 4.9 6.4 3.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3810) HMG_box PF00505.19 OQR81857.1 - 3.9 8.0 11.7 0.68 10.4 6.8 2.3 2 0 0 2 2 2 0 HMG (high mobility group) box LETM1 PF07766.13 OQR81857.1 - 6.7 6.0 8.6 12 5.2 8.6 1.3 1 0 0 1 1 1 0 LETM1-like protein D5_N PF08706.11 OQR81857.1 - 8.9 6.6 9.3 23 5.2 4.1 3.1 3 1 0 3 3 3 0 D5 N terminal like Mid2 PF04478.12 OQR81858.1 - 0.044 13.6 0.2 0.044 13.6 0.2 1.1 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor DBD_Tnp_Mut PF03108.15 OQR81859.1 - 0.11 12.5 0.1 7.2 6.7 0.0 2.2 2 0 0 2 2 2 0 MuDR family transposase DbpA PF03880.15 OQR81859.1 - 0.14 12.2 0.0 2.8 8.0 0.0 2.3 3 0 0 3 3 3 0 DbpA RNA binding domain Methyltransf_23 PF13489.6 OQR81860.1 - 2.3e-19 69.9 0.0 3e-19 69.5 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OQR81860.1 - 6.1e-16 58.9 0.0 2.1e-15 57.1 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 OQR81860.1 - 1.3e-13 51.4 0.0 2.7e-13 50.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OQR81860.1 - 1.1e-10 42.1 0.1 7.7e-10 39.4 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 OQR81860.1 - 3e-09 36.6 0.0 4.1e-09 36.1 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.6 OQR81860.1 - 2e-08 34.2 0.0 3.2e-08 33.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain TFCD_C PF12612.8 OQR81860.1 - 0.053 13.3 0.0 0.065 13.1 0.0 1.1 1 0 0 1 1 1 0 Tubulin folding cofactor D C terminal DREV PF05219.12 OQR81860.1 - 0.089 11.9 0.0 0.12 11.4 0.0 1.1 1 0 0 1 1 1 0 DREV methyltransferase MetW PF07021.12 OQR81860.1 - 0.12 12.0 0.1 0.18 11.3 0.1 1.3 1 1 0 1 1 1 0 Methionine biosynthesis protein MetW DUF111 PF01969.17 OQR81861.1 - 2.8e-133 444.6 0.0 3.9e-133 444.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function DUF111 CTP_synth_N PF06418.14 OQR81861.1 - 7.1e-106 353.4 5.1 1.8e-103 345.5 5.1 2.4 1 1 0 1 1 1 1 CTP synthase N-terminus AAR2 PF05282.11 OQR81861.1 - 2.1e-76 257.6 6.9 5.5e-75 253.0 6.9 2.2 1 1 0 1 1 1 1 AAR2 protein GATase PF00117.28 OQR81861.1 - 1.2e-50 172.0 2.4 1.2e-50 171.9 0.0 2.1 2 0 0 2 2 2 1 Glutamine amidotransferase class-I CbiA PF01656.23 OQR81861.1 - 0.16 12.0 0.0 0.33 11.0 0.0 1.6 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain MatE PF01554.18 OQR81862.1 - 1.6e-44 151.4 38.7 3.9e-23 81.9 8.3 3.2 4 0 0 4 4 4 2 MatE HD PF01966.22 OQR81863.1 - 0.13 12.4 0.0 0.23 11.7 0.0 1.3 1 0 0 1 1 1 0 HD domain Clr5 PF14420.6 OQR81864.1 - 0.15 12.3 0.1 0.54 10.5 0.0 2.0 2 0 0 2 2 2 0 Clr5 domain UPF0180 PF03698.13 OQR81866.1 - 0.027 14.6 0.4 0.14 12.4 0.0 2.3 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0180) DUF5575 PF17738.1 OQR81866.1 - 0.081 11.9 0.0 0.15 11.0 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5575) DUF2064 PF09837.9 OQR81866.1 - 0.19 11.6 0.0 1 9.2 0.0 2.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2064) FH2 PF02181.23 OQR81867.1 - 1.1e-91 307.8 0.7 1.1e-91 307.8 0.7 1.7 2 0 0 2 2 2 1 Formin Homology 2 Domain CCDC53 PF10152.9 OQR81867.1 - 8.1e-36 123.7 17.8 2.3e-13 50.9 0.2 4.7 5 0 0 5 5 5 3 Subunit CCDC53 of WASH complex CLP1_P PF16575.5 OQR81868.1 - 4.5e-41 140.7 0.0 8.6e-41 139.8 0.0 1.5 1 0 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop EF-hand_7 PF13499.6 OQR81868.1 - 7.6e-05 23.1 0.1 0.11 12.9 0.0 3.5 2 0 0 2 2 2 2 EF-hand domain pair p25-alpha PF05517.12 OQR81868.1 - 0.0026 18.0 0.0 1.6 8.9 0.0 3.1 3 0 0 3 3 3 1 p25-alpha DUF815 PF05673.13 OQR81868.1 - 0.0043 16.2 0.0 0.012 14.8 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF815) PulA_N1 PF17999.1 OQR81868.1 - 0.031 15.0 0.1 0.083 13.6 0.1 1.7 1 0 0 1 1 1 0 Pullulanase N1-terminal domain RNA_helicase PF00910.22 OQR81868.1 - 0.091 13.2 0.0 0.24 11.8 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_18 PF13238.6 OQR81868.1 - 0.094 13.3 0.0 0.25 11.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain EF-hand_6 PF13405.6 OQR81868.1 - 0.11 12.4 2.0 1.6 8.9 0.0 3.7 4 0 0 4 4 4 0 EF-hand domain AAA_16 PF13191.6 OQR81868.1 - 0.13 12.7 0.0 0.44 10.9 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain AAA_22 PF13401.6 OQR81868.1 - 0.16 12.2 0.0 0.55 10.5 0.0 1.9 1 0 0 1 1 1 0 AAA domain Phos_pyr_kin PF08543.12 OQR81869.1 - 2.3e-82 276.1 1.2 3.3e-82 275.6 1.2 1.2 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase TENA_THI-4 PF03070.16 OQR81869.1 - 4.3e-29 101.8 0.1 7.8e-29 101.0 0.1 1.4 1 0 0 1 1 1 1 TENA/THI-4/PQQC family HK PF02110.15 OQR81869.1 - 3e-06 26.8 0.9 5.6e-06 25.9 0.1 1.8 2 0 0 2 2 2 1 Hydroxyethylthiazole kinase family Carb_kinase PF01256.17 OQR81869.1 - 5.5e-05 22.8 0.8 0.00011 21.7 0.8 1.5 1 0 0 1 1 1 1 Carbohydrate kinase PX PF00787.24 OQR81870.1 - 5.5e-10 39.2 0.0 1.2e-09 38.1 0.0 1.5 1 0 0 1 1 1 1 PX domain TrmB PF01978.19 OQR81871.1 - 0.019 14.8 0.1 0.032 14.1 0.1 1.4 1 1 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB DUF4423 PF14394.6 OQR81871.1 - 0.035 13.8 0.0 0.04 13.6 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4423) MarR_2 PF12802.7 OQR81871.1 - 0.049 13.5 0.0 0.25 11.3 0.0 1.9 1 1 0 1 1 1 0 MarR family Nucleoside_tran PF01733.18 OQR81873.1 - 9e-22 77.8 12.4 3.5e-21 75.9 12.4 1.9 1 1 0 1 1 1 1 Nucleoside transporter Ion_trans PF00520.31 OQR81874.1 - 2e-129 430.1 56.3 2e-46 158.2 6.2 3.1 3 0 0 3 3 3 3 Ion transport protein PKD_channel PF08016.12 OQR81874.1 - 0.001 17.8 54.4 0.0028 16.4 1.5 8.8 6 3 3 9 9 9 6 Polycystin cation channel Lig_chan PF00060.26 OQR81874.1 - 0.73 9.7 9.1 7.5 6.4 0.1 4.0 3 1 0 3 3 3 0 Ligand-gated ion channel Glyco_hydro_20 PF00728.22 OQR81875.1 - 1.8e-93 313.8 0.1 2.6e-93 313.2 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.6 OQR81875.1 - 9.4e-11 42.5 0.4 2.5e-10 41.2 0.4 1.7 1 1 0 1 1 1 1 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.15 OQR81875.1 - 8.8e-08 33.0 0.7 3.1e-07 31.2 0.2 2.1 3 0 0 3 3 3 1 Glycosyl hydrolase family 20, domain 2 RecO_N_2 PF13114.6 OQR81875.1 - 0.074 12.8 0.0 0.23 11.2 0.0 1.7 2 0 0 2 2 2 0 RecO N terminal MFS_1 PF07690.16 OQR81876.1 - 2.3e-13 49.8 31.8 2.3e-13 49.8 31.8 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily CH PF00307.31 OQR81877.1 - 2.2e-19 69.7 0.0 2.7e-19 69.3 0.0 1.1 1 0 0 1 1 1 1 Calponin homology (CH) domain CDC24 PF06395.11 OQR81877.1 - 0.0059 16.8 0.0 0.0097 16.1 0.0 1.3 1 0 0 1 1 1 1 CDC24 Calponin Anoctamin PF04547.12 OQR81878.1 - 8.6e-82 275.4 20.8 1.1e-81 275.0 20.8 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel Anoct_dimer PF16178.5 OQR81878.1 - 0.0019 18.0 0.0 0.0033 17.2 0.0 1.4 1 0 0 1 1 1 1 Dimerisation domain of Ca+-activated chloride-channel, anoctamin tRNA-synt_2d PF01409.20 OQR81879.1 - 3.1e-49 167.7 0.3 6.7e-49 166.6 0.3 1.5 1 1 0 1 1 1 1 tRNA synthetases class II core domain (F) FDX-ACB PF03147.14 OQR81879.1 - 1.9e-25 89.1 0.0 7.1e-25 87.3 0.0 2.0 2 0 0 2 2 2 1 Ferredoxin-fold anticodon binding domain Pkinase PF00069.25 OQR81880.1 - 1.1e-63 215.1 0.1 1.3e-63 214.9 0.1 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQR81880.1 - 3.3e-43 147.8 0.0 4e-43 147.6 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 OQR81880.1 - 3.3e-06 26.3 0.7 7.3e-06 25.2 0.7 1.5 1 1 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 OQR81880.1 - 1.7e-05 23.8 0.0 2.6e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 OQR81880.1 - 0.00049 19.5 0.0 0.00074 18.9 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pox_ser-thr_kin PF05445.11 OQR81880.1 - 0.0033 16.5 0.4 0.0044 16.1 0.4 1.2 1 0 0 1 1 1 1 Poxvirus serine/threonine protein kinase Kdo PF06293.14 OQR81880.1 - 0.0051 16.2 0.3 0.0071 15.7 0.3 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OQR81880.1 - 0.02 14.8 0.0 0.62 9.9 0.1 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family RIO1 PF01163.22 OQR81880.1 - 0.034 13.7 0.1 0.049 13.2 0.1 1.2 1 0 0 1 1 1 0 RIO1 family Na_Ca_ex PF01699.24 OQR81881.1 - 6.4e-20 71.7 16.7 6.4e-20 71.7 16.7 1.6 1 1 1 2 2 2 2 Sodium/calcium exchanger protein zf-CCHC_3 PF13917.6 OQR81882.1 - 1.9e-19 69.3 1.8 4e-19 68.3 1.8 1.6 1 0 0 1 1 1 1 Zinc knuckle SR-25 PF10500.9 OQR81882.1 - 0.0052 16.4 29.8 0.0064 16.1 29.8 1.2 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein AF-4 PF05110.13 OQR81882.1 - 0.015 13.4 30.6 0.014 13.5 30.6 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein zf-CCHC_5 PF14787.6 OQR81882.1 - 0.048 13.4 2.4 0.092 12.5 2.4 1.4 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger TLP-20 PF06088.11 OQR81882.1 - 0.16 11.8 6.0 0.16 11.9 6.0 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) zf-CCHC PF00098.23 OQR81882.1 - 0.2 11.8 1.1 0.29 11.3 1.1 1.3 1 0 0 1 1 1 0 Zinc knuckle FancD2 PF14631.6 OQR81882.1 - 0.75 7.1 8.9 0.78 7.1 8.9 1.0 1 0 0 1 1 1 0 Fanconi anaemia protein FancD2 nuclease SAPS PF04499.15 OQR81882.1 - 0.82 8.4 5.2 0.74 8.5 5.2 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Smg8_Smg9 PF10220.9 OQR81882.1 - 1.2 7.3 11.8 1.5 7.0 11.8 1.2 1 0 0 1 1 1 0 Smg8_Smg9 Macoilin PF09726.9 OQR81882.1 - 3 6.3 17.8 3 6.3 17.8 1.0 1 0 0 1 1 1 0 Macoilin family Peroxin-3 PF04882.12 OQR81882.1 - 3.5 6.5 14.3 3.3 6.6 14.3 1.0 1 0 0 1 1 1 0 Peroxin-3 NPR3 PF03666.13 OQR81882.1 - 3.6 6.3 12.5 3.7 6.2 12.5 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 DUF4614 PF15391.6 OQR81882.1 - 4.6 7.2 21.1 5.4 7.0 21.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) Menin PF05053.13 OQR81882.1 - 5.6 5.2 9.7 5.4 5.3 9.7 1.0 1 0 0 1 1 1 0 Menin CCDC106 PF15794.5 OQR81882.1 - 6.8 6.3 21.4 8.8 6.0 21.4 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 Macro_2 PF14519.6 OQR81884.1 - 0.011 15.1 0.1 0.02 14.3 0.1 1.3 1 0 0 1 1 1 0 Macro-like domain DUF16 PF01519.16 OQR81885.1 - 0.0046 17.4 0.2 0.0046 17.4 0.2 9.0 11 2 1 12 12 12 1 Protein of unknown function DUF16 Nmad3 PF18754.1 OQR81885.1 - 0.11 12.0 0.9 4.4 6.8 0.2 3.0 2 0 0 2 2 2 0 Nucleotide modification associated domain 3 BTK PF00779.19 OQR81885.1 - 6.1 6.8 5.1 2 8.3 1.1 2.2 2 0 0 2 2 2 0 BTK motif Pkinase PF00069.25 OQR81886.1 - 3.8e-57 193.7 0.0 7.5e-57 192.7 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQR81886.1 - 1.6e-38 132.5 0.0 2.8e-38 131.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase SAM_2 PF07647.17 OQR81886.1 - 2.5e-09 37.1 0.4 4.8e-09 36.2 0.4 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 OQR81886.1 - 2.2e-06 28.0 0.2 4.9e-06 26.9 0.2 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Pkinase_fungal PF17667.1 OQR81886.1 - 4.2e-05 22.5 0.0 8.1e-05 21.6 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase zf-B_box PF00643.24 OQR81886.1 - 0.00012 22.1 6.2 0.00026 21.1 6.2 1.5 1 0 0 1 1 1 1 B-box zinc finger CEBP_ZZ PF16366.5 OQR81886.1 - 0.0043 17.3 4.5 0.0096 16.1 4.5 1.5 1 0 0 1 1 1 1 Cytoplasmic polyadenylation element-binding protein ZZ domain SAM_PNT PF02198.16 OQR81886.1 - 0.012 15.6 0.2 0.027 14.4 0.2 1.6 1 0 0 1 1 1 0 Sterile alpha motif (SAM)/Pointed domain Haspin_kinase PF12330.8 OQR81886.1 - 0.012 14.5 0.0 0.024 13.6 0.0 1.4 1 0 0 1 1 1 0 Haspin like kinase domain Seadorna_VP7 PF07387.11 OQR81886.1 - 0.03 13.4 0.0 0.048 12.7 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 SAM_3 PF18016.1 OQR81886.1 - 0.059 13.2 0.5 0.25 11.2 0.1 2.1 2 0 0 2 2 2 0 SAM domain (Sterile alpha motif) Kdo PF06293.14 OQR81886.1 - 0.15 11.4 0.0 0.32 10.3 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family SHOCT PF09851.9 OQR81886.1 - 2.7 7.8 6.0 5.2 6.9 0.1 3.4 3 0 0 3 3 3 0 Short C-terminal domain RabGAP-TBC PF00566.18 OQR81887.1 - 1.9e-30 106.1 2.3 2.9e-16 59.8 1.4 2.2 2 0 0 2 2 2 2 Rab-GTPase-TBC domain PH PF00169.29 OQR81887.1 - 0.002 18.6 0.0 0.0045 17.5 0.0 1.7 1 0 0 1 1 1 1 PH domain SQHop_cyclase_N PF13249.6 OQR81887.1 - 0.0093 15.1 0.1 0.016 14.4 0.1 1.3 1 0 0 1 1 1 1 Squalene-hopene cyclase N-terminal domain PH_8 PF15409.6 OQR81887.1 - 0.018 15.3 0.1 0.049 13.9 0.1 1.7 1 0 0 1 1 1 0 Pleckstrin homology domain Pkinase PF00069.25 OQR81889.1 - 2.3e-54 184.5 0.0 4.4e-50 170.5 0.0 2.5 2 1 1 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 OQR81889.1 - 4.3e-29 101.6 0.0 1.3e-27 96.8 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OQR81889.1 - 2.8e-05 23.1 0.0 4.6e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 OQR81889.1 - 0.00035 20.0 0.0 0.00058 19.3 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Elicitin PF00964.17 OQR81889.1 - 0.074 13.2 0.0 0.43 10.7 0.0 2.3 2 0 0 2 2 2 0 Elicitin CAP PF00188.26 OQR81889.1 - 0.08 13.8 0.9 0.15 12.9 0.9 1.4 1 0 0 1 1 1 0 Cysteine-rich secretory protein family MFS_2 PF13347.6 OQR81890.1 - 4.3e-27 94.8 28.3 6.8e-21 74.3 4.6 2.2 2 0 0 2 2 2 2 MFS/sugar transport protein MFS_1 PF07690.16 OQR81890.1 - 1.8e-17 63.4 23.1 5e-11 42.1 9.7 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 OQR81890.1 - 0.00044 19.3 23.7 0.0018 17.2 8.0 2.2 2 0 0 2 2 2 2 Sugar (and other) transporter NAGLU PF05089.12 OQR81892.1 - 1.2e-127 425.5 7.7 2.1e-127 424.7 7.7 1.4 1 0 0 1 1 1 1 Alpha-N-acetylglucosaminidase (NAGLU) tim-barrel domain NAGLU_C PF12972.7 OQR81892.1 - 1.6e-62 211.5 0.5 2.9e-62 210.6 0.5 1.4 1 0 0 1 1 1 1 Alpha-N-acetylglucosaminidase (NAGLU) C-terminal domain NAGLU_N PF12971.7 OQR81892.1 - 1.3e-15 57.0 0.0 3.3e-15 55.6 0.0 1.8 1 0 0 1 1 1 1 Alpha-N-acetylglucosaminidase (NAGLU) N-terminal domain p450 PF00067.22 OQR81893.1 - 5e-77 259.6 0.1 6e-77 259.3 0.1 1.0 1 0 0 1 1 1 1 Cytochrome P450 Pkinase PF00069.25 OQR81894.1 - 6e-65 219.2 0.0 1.1e-64 218.4 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQR81894.1 - 1.5e-33 116.2 0.0 2.4e-33 115.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase PH PF00169.29 OQR81894.1 - 2.5e-07 31.2 0.2 6.7e-07 29.8 0.0 1.9 2 0 0 2 2 2 1 PH domain PH_8 PF15409.6 OQR81894.1 - 2.5e-05 24.4 0.0 5.2e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain Haspin_kinase PF12330.8 OQR81894.1 - 0.0023 17.0 0.3 0.0035 16.4 0.3 1.3 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 OQR81894.1 - 0.0023 17.3 0.3 0.0041 16.5 0.3 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OQR81894.1 - 0.049 13.5 0.0 0.099 12.5 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family PhzC-PhzF PF02567.16 OQR81894.1 - 0.059 12.8 0.0 0.091 12.2 0.0 1.3 1 0 0 1 1 1 0 Phenazine biosynthesis-like protein YukC PF10140.9 OQR81894.1 - 0.084 11.7 0.0 0.13 11.1 0.0 1.2 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukC Pox_ser-thr_kin PF05445.11 OQR81894.1 - 0.1 11.6 1.1 0.19 10.7 0.4 1.7 2 0 0 2 2 2 0 Poxvirus serine/threonine protein kinase Med30 PF11315.8 OQR81895.1 - 0.0016 18.7 0.9 0.0022 18.2 0.9 1.3 1 0 0 1 1 1 1 Mediator complex subunit 30 Herpes_BLRF2 PF05812.12 OQR81895.1 - 0.01 15.9 0.9 0.021 15.0 0.9 1.6 1 0 0 1 1 1 0 Herpesvirus BLRF2 protein Ank_2 PF12796.7 OQR81896.1 - 3.7e-14 53.1 0.1 5.5e-08 33.3 0.0 2.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 OQR81896.1 - 2.7e-11 43.4 0.0 0.00021 21.6 0.0 3.3 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.6 OQR81896.1 - 9e-11 42.1 0.1 1.2e-05 25.8 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQR81896.1 - 1.9e-10 40.0 0.0 0.0003 21.0 0.0 3.9 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 OQR81896.1 - 3.3e-06 27.2 0.3 0.48 10.8 0.2 3.3 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Melibiase_2 PF16499.5 OQR81899.1 - 2e-41 142.0 0.0 3.1e-41 141.4 0.0 1.2 1 0 0 1 1 1 1 Alpha galactosidase A Melibiase PF02065.18 OQR81899.1 - 0.00088 18.3 0.1 0.0018 17.3 0.1 1.4 1 0 0 1 1 1 1 Melibiase WD40 PF00400.32 OQR81900.1 - 1.6e-17 63.5 7.9 0.0002 22.1 0.0 6.7 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OQR81900.1 - 4.1e-15 55.8 0.0 5.1e-05 23.5 0.0 5.8 1 1 5 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 OQR81900.1 - 0.0073 15.3 0.4 6.8 5.6 0.0 3.3 2 1 2 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein PQQ_3 PF13570.6 OQR81900.1 - 0.31 11.6 5.2 18 6.0 0.0 3.4 3 1 0 3 3 3 0 PQQ-like domain ATG101 PF07855.12 OQR81902.1 - 3.4e-33 114.8 0.2 4e-33 114.6 0.2 1.0 1 0 0 1 1 1 1 Autophagy-related protein 101 Transposase_22 PF02994.14 OQR81902.1 - 0.14 12.4 0.7 0.24 11.6 0.3 1.5 2 0 0 2 2 2 0 L1 transposable element RBD-like domain FtsA PF14450.6 OQR81903.1 - 0.034 14.6 0.1 0.12 12.8 0.1 1.9 1 1 1 2 2 2 0 Cell division protein FtsA Biopterin_H PF00351.21 OQR81905.1 - 1.9e-141 470.9 0.1 2.4e-141 470.6 0.1 1.1 1 0 0 1 1 1 1 Biopterin-dependent aromatic amino acid hydroxylase ACT PF01842.25 OQR81905.1 - 0.00023 20.9 0.0 0.00046 19.9 0.0 1.6 1 0 0 1 1 1 1 ACT domain ACT_4 PF13291.6 OQR81905.1 - 0.051 14.2 0.0 0.11 13.1 0.0 1.5 1 0 0 1 1 1 0 ACT domain DUF4380 PF14315.6 OQR81905.1 - 0.081 11.8 0.0 0.12 11.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4380) Cation_ATPase_C PF00689.21 OQR81907.1 - 9e-38 129.8 4.9 9e-38 129.8 4.9 2.5 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 OQR81907.1 - 9.4e-37 126.3 1.4 2.1e-36 125.2 0.0 2.3 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase PF13246.6 OQR81907.1 - 1e-17 64.0 0.0 2.1e-17 63.0 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 OQR81907.1 - 1.9e-16 61.0 0.0 8.7e-16 58.8 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 OQR81907.1 - 1.5e-14 53.4 0.0 3.7e-14 52.2 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 OQR81907.1 - 0.001 18.8 0.3 0.037 13.8 0.1 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Homeobox_KN PF05920.11 OQR81908.1 - 1.1e-33 114.8 0.7 3.9e-16 58.7 0.1 2.8 2 0 0 2 2 2 2 Homeobox KN domain Homeodomain PF00046.29 OQR81908.1 - 2.3e-12 46.5 3.4 2.1e-05 24.3 0.1 3.0 3 0 0 3 3 3 2 Homeodomain Homez PF11569.8 OQR81908.1 - 0.0069 15.8 0.0 0.77 9.3 0.0 2.6 2 0 0 2 2 2 2 Homeodomain leucine-zipper encoding, Homez UCH PF00443.29 OQR81909.1 - 5.5e-57 193.2 0.2 6.5e-57 192.9 0.2 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 OQR81909.1 - 6.7e-16 58.8 0.5 1.1e-15 58.1 0.5 1.3 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-GRF PF06839.12 OQR81909.1 - 2.4e-12 46.7 3.1 2.4e-12 46.7 3.1 2.0 2 0 0 2 2 2 1 GRF zinc finger zf-C4_Topoisom PF01396.19 OQR81909.1 - 0.0063 16.3 0.3 0.0063 16.3 0.3 2.8 3 0 0 3 3 3 1 Topoisomerase DNA binding C4 zinc finger Peptidase_C98 PF15499.6 OQR81909.1 - 0.28 10.6 8.1 3.6 7.0 0.0 4.0 3 1 1 4 4 4 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase DUF1126 PF06565.12 OQR81910.1 - 2e-76 252.6 0.0 1.8e-26 92.0 0.0 3.5 3 0 0 3 3 3 3 DUF1126 PH-like domain EF-hand_1 PF00036.32 OQR81910.1 - 0.004 16.6 0.2 0.043 13.4 0.2 2.8 3 0 0 3 3 3 1 EF hand EF-hand_7 PF13499.6 OQR81910.1 - 0.016 15.6 0.1 0.12 12.9 0.1 2.3 2 0 0 2 2 2 0 EF-hand domain pair DUF2375 PF09558.10 OQR81910.1 - 0.12 12.4 0.1 0.35 10.9 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2375) DUF1993 PF09351.10 OQR81910.1 - 0.13 12.4 0.6 0.35 11.0 0.6 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1993) EF-hand_6 PF13405.6 OQR81910.1 - 0.15 12.1 0.4 2.5 8.3 0.2 3.1 4 0 0 4 4 4 0 EF-hand domain DUF4598 PF15370.6 OQR81910.1 - 5 7.6 0.0 5 7.6 0.0 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4598) PseudoU_synth_2 PF00849.22 OQR81911.1 - 5.2e-23 81.9 0.0 1.3e-22 80.6 0.0 1.7 1 1 0 1 1 1 1 RNA pseudouridylate synthase Ank_2 PF12796.7 OQR81912.1 - 4.1e-19 69.0 0.4 9.9e-14 51.7 0.1 2.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 OQR81912.1 - 6.2e-19 67.5 3.5 7.9e-08 32.4 0.1 3.3 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.6 OQR81912.1 - 2.4e-15 56.4 0.1 2.5e-11 43.6 0.0 2.5 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQR81912.1 - 8.5e-14 50.3 0.2 0.00051 20.3 0.0 3.6 4 0 0 4 4 4 3 Ankyrin repeat Ank_4 PF13637.6 OQR81912.1 - 1.3e-12 47.9 0.1 9.1e-10 38.9 0.0 2.6 2 1 1 3 3 3 3 Ankyrin repeats (many copies) PEGA PF08308.11 OQR81912.1 - 0.016 15.1 0.0 5.9 6.9 0.0 2.9 2 1 1 3 3 3 0 PEGA domain Ank_2 PF12796.7 OQR81913.1 - 2.8e-116 380.3 34.6 7.5e-16 58.5 1.1 10.2 2 2 8 10 10 10 10 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQR81913.1 - 1.1e-82 271.4 21.9 9.9e-10 38.8 0.1 16.0 6 5 11 17 17 17 17 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQR81913.1 - 6.3e-81 256.6 24.1 0.00018 21.7 0.0 21.8 21 1 0 21 21 21 16 Ankyrin repeat Ank PF00023.30 OQR81913.1 - 1e-75 247.1 31.3 4.1e-05 23.8 0.0 21.5 21 1 0 21 21 21 18 Ankyrin repeat Ank_5 PF13857.6 OQR81913.1 - 1.5e-71 235.5 33.5 1e-06 28.9 0.0 18.5 2 2 17 20 20 20 19 Ankyrin repeats (many copies) EccE PF11203.8 OQR81913.1 - 0.0088 16.3 0.1 3.4 8.1 0.0 3.0 2 1 0 2 2 2 1 Putative type VII ESX secretion system translocon, EccE RNase_P_pop3 PF08228.11 OQR81913.1 - 0.062 13.4 6.1 0.14 12.2 0.2 3.6 3 1 0 3 3 3 0 RNase P subunit Pop3 Nitro_FeMo-Co PF02579.17 OQR81913.1 - 0.25 11.7 1.4 25 5.3 0.0 4.4 4 1 0 5 5 5 0 Dinitrogenase iron-molybdenum cofactor DUF2170 PF09938.9 OQR81913.1 - 0.81 9.4 4.5 23 4.7 0.0 4.3 4 0 0 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2170) Imm_superinfect PF14373.6 OQR81913.1 - 1.7 8.7 4.8 41 4.2 0.1 5.1 7 0 0 7 7 7 0 Superinfection immunity protein Tubulin PF00091.25 OQR81914.1 - 7.7e-34 117.6 0.8 1.3e-33 116.8 0.8 1.4 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain FtsZ_C PF12327.8 OQR81914.1 - 1.9e-29 101.8 0.2 4.3e-29 100.6 0.2 1.7 1 0 0 1 1 1 1 FtsZ family, C-terminal domain Aa_trans PF01490.18 OQR81916.1 - 3.8e-64 216.9 36.2 4.6e-64 216.6 36.2 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 OQR81916.1 - 6.3e-09 35.4 32.2 1.1e-07 31.3 32.2 2.3 1 1 0 1 1 1 1 Tryptophan/tyrosine permease family Aa_trans PF01490.18 OQR81917.1 - 1.2e-67 228.4 36.3 1.4e-67 228.2 36.3 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 OQR81917.1 - 1.8e-10 40.4 33.4 1.9e-09 37.1 33.4 2.0 1 1 0 1 1 1 1 Tryptophan/tyrosine permease family DEAD_2 PF06733.15 OQR81918.1 - 2e-53 180.6 0.8 3.2e-53 180.0 0.8 1.3 1 0 0 1 1 1 1 DEAD_2 Helicase_C_2 PF13307.6 OQR81918.1 - 1.5e-07 31.8 0.0 4.1e-07 30.3 0.0 1.7 1 0 0 1 1 1 1 Helicase C-terminal domain DEAD PF00270.29 OQR81918.1 - 7.6e-06 25.8 0.1 0.014 15.2 0.0 3.2 3 1 0 3 3 3 2 DEAD/DEAH box helicase ResIII PF04851.15 OQR81918.1 - 2.3e-05 24.5 0.1 0.01 15.9 0.0 2.6 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit PhoH PF02562.16 OQR81918.1 - 0.086 12.3 0.1 12 5.3 0.0 2.3 2 0 0 2 2 2 0 PhoH-like protein zf-like PF04071.12 OQR81918.1 - 0.19 11.7 1.8 0.27 11.2 0.1 2.1 2 0 0 2 2 2 0 Cysteine-rich small domain Phage_holin_Dp1 PF16938.5 OQR81919.1 - 0.53 10.5 4.2 3.4 8.0 0.3 2.6 1 1 1 2 2 2 0 Putative phage holin Dp-1 Aa_trans PF01490.18 OQR81920.1 - 2.4e-63 214.2 34.4 2.9e-63 214.0 34.4 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 OQR81920.1 - 7.6e-10 38.4 32.6 7.4e-09 35.1 32.6 2.0 1 1 0 1 1 1 1 Tryptophan/tyrosine permease family Ank_2 PF12796.7 OQR81922.1 - 0.00091 19.8 0.6 0.0015 19.0 0.6 1.3 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Capsid_N PF16903.5 OQR81922.1 - 0.065 12.8 0.0 0.068 12.8 0.0 1.1 1 0 0 1 1 1 0 Major capsid protein N-terminus Ank PF00023.30 OQR81922.1 - 0.11 13.0 0.6 0.32 11.5 0.6 2.0 1 1 0 1 1 1 0 Ankyrin repeat RIX1 PF08167.12 OQR81923.1 - 5.6e-10 39.3 1.4 5.6e-10 39.3 1.4 1.8 2 0 0 2 2 2 1 rRNA processing/ribosome biogenesis PUNUT PF16913.5 OQR81923.1 - 0.0033 16.7 0.3 0.0059 15.9 0.3 1.3 1 0 0 1 1 1 1 Purine nucleobase transmembrane transport CRM1_C PF08767.11 OQR81923.1 - 0.0078 15.4 0.1 0.016 14.4 0.1 1.7 1 0 0 1 1 1 1 CRM1 C terminal DUF4042 PF13251.6 OQR81923.1 - 0.05 13.3 5.3 0.031 14.0 0.9 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4042) DNA_pol_phi PF04931.13 OQR81923.1 - 7.9 4.4 23.9 2 6.4 20.1 1.9 2 0 0 2 2 2 0 DNA polymerase phi DUF2722 PF10846.8 OQR81923.1 - 7.9 5.3 14.1 14 4.5 14.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Pho88 PF10032.9 OQR81924.1 - 8.6e-32 109.9 0.1 1.5e-31 109.0 0.1 1.3 1 0 0 1 1 1 1 Phosphate transport (Pho88) Ank_2 PF12796.7 OQR81924.1 - 1.1e-15 57.9 0.0 5.2e-12 46.2 0.0 2.6 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OQR81924.1 - 8.4e-10 38.7 0.0 0.00015 21.9 0.0 2.7 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 OQR81924.1 - 9.8e-09 35.3 0.0 0.021 15.3 0.0 3.4 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.6 OQR81924.1 - 1.2e-08 35.3 0.0 5.1e-06 26.9 0.0 2.9 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQR81924.1 - 1e-07 31.6 0.0 0.072 13.7 0.0 3.6 4 0 0 4 4 4 2 Ankyrin repeat HAD_2 PF13419.6 OQR81926.1 - 6.7e-20 71.9 0.0 4.8e-19 69.1 0.0 2.0 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 OQR81926.1 - 1.7e-16 61.2 0.0 5.3e-15 56.3 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 OQR81926.1 - 5e-08 32.9 0.0 1.2e-07 31.6 0.0 1.6 1 0 0 1 1 1 1 HAD-hyrolase-like HAD PF12710.7 OQR81926.1 - 3.3e-05 24.4 0.0 7.3e-05 23.2 0.0 1.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Ank_2 PF12796.7 OQR81928.1 - 3.2e-21 75.7 0.9 6.4e-10 39.5 0.1 2.6 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 OQR81928.1 - 3.3e-15 55.7 3.7 7.9e-07 29.3 0.1 5.3 5 0 0 5 5 5 3 Ankyrin repeat Ank_4 PF13637.6 OQR81928.1 - 2.9e-14 53.2 0.1 9.5e-07 29.3 0.0 3.7 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Myb_DNA-binding PF00249.31 OQR81928.1 - 1.1e-11 44.7 0.4 1.8e-05 24.8 0.0 3.0 2 0 0 2 2 2 2 Myb-like DNA-binding domain Ank_5 PF13857.6 OQR81928.1 - 1.4e-10 41.2 0.3 0.00034 20.8 0.1 3.3 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQR81928.1 - 1.7e-08 34.0 2.2 0.016 15.6 0.0 4.8 5 0 0 5 5 5 2 Ankyrin repeat Myb_DNA-bind_6 PF13921.6 OQR81928.1 - 3.2e-08 33.7 0.6 0.012 15.8 0.0 3.4 3 0 0 3 3 3 2 Myb-like DNA-binding domain Mpp10 PF04006.12 OQR81928.1 - 4.9 5.5 30.2 5 5.5 2.4 2.4 2 0 0 2 2 2 0 Mpp10 protein zf-Nse PF11789.8 OQR81930.1 - 3.4e-15 55.6 0.2 6.9e-15 54.6 0.2 1.5 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit U-box PF04564.15 OQR81930.1 - 5.6e-05 23.2 0.0 0.00012 22.2 0.0 1.5 1 0 0 1 1 1 1 U-box domain zf-RING_UBOX PF13445.6 OQR81930.1 - 6e-05 23.0 0.1 0.00011 22.1 0.1 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 OQR81930.1 - 0.00037 20.3 0.1 0.00084 19.1 0.1 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Rtf2 PF04641.12 OQR81930.1 - 0.0094 15.3 1.0 0.013 14.9 0.1 1.8 2 0 0 2 2 2 1 Rtf2 RING-finger zf-MIZ PF02891.20 OQR81930.1 - 0.011 15.4 0.1 0.028 14.2 0.1 1.6 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger zf-rbx1 PF12678.7 OQR81930.1 - 0.013 15.8 0.2 0.031 14.6 0.2 1.7 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-RING_2 PF13639.6 OQR81930.1 - 0.023 15.0 0.2 0.043 14.2 0.2 1.5 1 0 0 1 1 1 0 Ring finger domain ASH PF15780.5 OQR81932.1 - 3.9e-49 164.9 24.2 0.00036 20.7 0.0 21.9 23 2 1 25 25 25 12 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin PapD-like PF14874.6 OQR81932.1 - 9.7e-20 70.6 7.8 0.25 11.5 0.0 12.0 13 0 0 13 13 13 6 Flagellar-associated PapD-like DUF1573 PF07610.11 OQR81932.1 - 7.8e-15 54.7 0.0 3.1 7.9 0.1 13.7 15 0 0 15 15 15 2 Protein of unknown function (DUF1573) Motile_Sperm PF00635.26 OQR81932.1 - 7.4e-13 48.3 14.8 0.017 14.9 0.0 12.6 13 1 0 13 13 13 4 MSP (Major sperm protein) domain TMEM131_like PF12371.8 OQR81932.1 - 5.2e-06 26.6 13.8 0.79 10.0 0.0 10.3 14 0 0 14 14 14 2 Transmembrane protein 131-like MYCBPAP PF14646.6 OQR81932.1 - 3.7e-05 22.9 5.0 0.57 9.1 0.0 8.4 10 1 0 11 11 11 1 MYCBP-associated protein family DUF5001 PF16392.5 OQR81932.1 - 0.00058 19.7 4.0 7 6.6 0.0 7.9 9 0 0 9 9 9 1 Ig-like domain WIF PF02019.18 OQR81932.1 - 0.074 12.7 0.5 4.7 6.9 0.0 4.0 4 0 0 4 4 4 0 WIF domain RNase_T PF00929.24 OQR81934.1 - 1.9e-06 28.6 0.1 6.3e-06 26.8 0.1 1.9 1 1 0 1 1 1 1 Exonuclease Ammonium_transp PF00909.21 OQR81935.1 - 4.7e-32 111.2 34.8 5.8e-32 110.9 34.0 1.5 1 1 1 2 2 2 1 Ammonium Transporter Family Myotub-related PF06602.14 OQR81936.1 - 8.6e-128 426.2 0.0 1.4e-127 425.5 0.0 1.3 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain DSPc PF00782.20 OQR81936.1 - 0.00016 21.5 0.0 0.00045 20.1 0.0 1.8 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 OQR81936.1 - 0.00043 19.9 0.1 0.00075 19.1 0.1 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 OQR81936.1 - 0.00091 19.3 0.0 0.0016 18.4 0.0 1.4 1 0 0 1 1 1 1 Tyrosine phosphatase family GRAM PF02893.20 OQR81936.1 - 0.091 12.7 0.8 0.5 10.3 0.1 2.6 3 1 0 3 3 3 0 GRAM domain HECT PF00632.25 OQR81938.1 - 3.4e-59 200.8 0.0 4.9e-59 200.3 0.0 1.1 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Kinesin PF00225.23 OQR81939.1 - 2.4e-103 345.6 0.4 5.2e-103 344.5 0.3 1.6 2 0 0 2 2 2 1 Kinesin motor domain NIF PF03031.18 OQR81939.1 - 5.7e-42 143.1 0.1 1e-41 142.3 0.1 1.4 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Microtub_bd PF16796.5 OQR81939.1 - 1.4e-24 86.8 1.6 4e-24 85.3 0.1 2.2 2 0 0 2 2 2 1 Microtubule binding ExsD PF16806.5 OQR81939.1 - 0.028 14.3 0.6 0.055 13.4 0.6 1.4 1 0 0 1 1 1 0 Antiactivator protein ExsD Cnn_1N PF07989.11 OQR81939.1 - 0.14 12.3 1.7 0.37 11.0 1.7 1.7 1 0 0 1 1 1 0 Centrosomin N-terminal motif 1 bZIP_2 PF07716.15 OQR81939.1 - 0.75 9.9 4.1 3.7 7.7 2.7 2.4 2 0 0 2 2 2 0 Basic region leucine zipper DivIC PF04977.15 OQR81939.1 - 0.93 9.3 4.8 0.67 9.8 1.9 2.1 1 1 1 2 2 2 0 Septum formation initiator CHAP PF05257.16 OQR81940.1 - 1.6e-13 51.0 0.2 2.9e-13 50.2 0.2 1.4 1 0 0 1 1 1 1 CHAP domain Caskin-Pro-rich PF16907.5 OQR81941.1 - 0.17 12.4 1.7 0.26 11.8 1.7 1.3 1 0 0 1 1 1 0 Proline rich region of Caskin proteins Xpo1 PF08389.12 OQR81942.1 - 8.2e-05 22.7 1.3 0.011 15.7 0.0 4.2 4 2 1 5 5 5 1 Exportin 1-like protein Importin_rep_3 PF18806.1 OQR81942.1 - 0.0078 16.2 0.1 0.16 12.0 0.0 3.2 2 1 1 3 3 3 1 Importin 13 repeat Fe-ADH PF00465.19 OQR81942.1 - 0.17 10.7 0.1 0.26 10.0 0.1 1.3 1 0 0 1 1 1 0 Iron-containing alcohol dehydrogenase Ank_2 PF12796.7 OQR81943.1 - 2.8e-40 136.8 3.4 2e-14 53.9 0.1 3.3 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQR81943.1 - 3.4e-36 123.1 4.5 1.6e-10 41.3 0.1 4.3 2 2 3 5 5 5 5 Ankyrin repeats (many copies) Ank PF00023.30 OQR81943.1 - 4.2e-32 109.2 4.4 5.9e-07 29.7 0.1 6.1 6 0 0 6 6 6 5 Ankyrin repeat Ank_3 PF13606.6 OQR81943.1 - 5.3e-27 90.9 0.1 0.0033 17.8 0.0 6.1 6 0 0 6 6 6 6 Ankyrin repeat Ank_5 PF13857.6 OQR81943.1 - 2.3e-24 85.1 2.7 3e-06 27.4 0.0 5.6 1 1 5 6 6 6 6 Ankyrin repeats (many copies) VWA_3_C PF18571.1 OQR81943.1 - 0.54 10.2 2.8 49 3.9 0.0 3.7 4 0 0 4 4 4 0 von Willebrand factor type A C-terminal domain Ank_2 PF12796.7 OQR81944.1 - 5.2e-37 126.3 5.1 6.8e-15 55.4 0.0 3.8 2 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.30 OQR81944.1 - 6.8e-31 105.3 5.4 7.1e-06 26.2 0.0 6.6 6 1 0 6 6 6 6 Ankyrin repeat Ank_3 PF13606.6 OQR81944.1 - 1.1e-23 80.7 1.4 0.0004 20.6 0.1 7.0 6 1 1 7 7 7 4 Ankyrin repeat Ank_4 PF13637.6 OQR81944.1 - 1.7e-23 82.6 1.7 1.5e-06 28.6 0.0 4.9 2 2 3 5 5 5 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 OQR81944.1 - 1e-18 67.1 1.3 0.0052 17.1 0.0 5.4 3 2 3 6 6 6 6 Ankyrin repeats (many copies) Ank_2 PF12796.7 OQR81945.1 - 9.6e-52 173.5 14.8 2.7e-18 66.3 0.4 4.8 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQR81945.1 - 9.8e-37 124.9 0.6 4.9e-11 42.9 0.0 5.1 3 1 2 5 5 5 4 Ankyrin repeats (many copies) Ank PF00023.30 OQR81945.1 - 9.7e-35 117.5 10.7 1.6e-07 31.5 0.0 7.1 6 1 0 6 6 6 5 Ankyrin repeat Ank_5 PF13857.6 OQR81945.1 - 7.9e-32 108.9 3.7 1.3e-09 38.1 0.0 6.7 1 1 6 7 7 7 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQR81945.1 - 6.5e-31 102.9 0.6 0.0032 17.8 0.0 7.1 7 0 0 7 7 7 6 Ankyrin repeat MauJ PF17419.2 OQR81945.1 - 0.0053 16.3 0.1 0.13 11.7 0.0 2.1 1 1 1 2 2 2 1 Methylamine utilization protein MauJ DUF4197 PF13852.6 OQR81945.1 - 0.013 15.1 0.1 0.08 12.6 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4197) PTS_IIA PF02255.16 OQR81945.1 - 0.23 11.5 1.3 0.49 10.5 0.7 1.9 1 1 0 1 1 1 0 PTS system, Lactose/Cellobiose specific IIA subunit Ank_2 PF12796.7 OQR81946.1 - 8.8e-16 58.3 0.3 1.1e-09 38.7 0.1 2.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 OQR81946.1 - 1.8e-15 56.6 1.9 5.6e-05 23.4 0.5 3.3 3 0 0 3 3 3 3 Ankyrin repeat Ank_3 PF13606.6 OQR81946.1 - 1.6e-14 52.6 0.8 0.0075 16.7 0.0 3.5 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.6 OQR81946.1 - 2.7e-13 49.9 0.4 0.0029 17.9 0.0 3.2 3 0 0 3 3 3 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 OQR81946.1 - 1.8e-10 41.1 1.1 1.9e-05 25.1 0.4 3.1 2 1 0 2 2 2 2 Ankyrin repeats (many copies) DUF1487 PF07368.11 OQR81946.1 - 0.018 14.5 0.2 0.026 14.0 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1487) Ank_2 PF12796.7 OQR81947.1 - 3.7e-33 114.0 4.7 1.1e-20 74.0 0.5 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 OQR81947.1 - 2.7e-27 94.0 1.1 3.3e-06 27.3 0.1 4.1 4 0 0 4 4 4 4 Ankyrin repeat Ank_4 PF13637.6 OQR81947.1 - 1e-26 92.9 1.4 1.4e-11 44.7 0.0 3.1 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 OQR81947.1 - 2.7e-23 81.7 0.1 6.2e-05 23.2 0.0 4.1 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQR81947.1 - 2.9e-23 79.4 0.0 0.00016 21.8 0.0 4.2 4 0 0 4 4 4 4 Ankyrin repeat VWA_3_C PF18571.1 OQR81947.1 - 0.016 15.0 2.6 15 5.5 0.1 4.0 4 0 0 4 4 4 0 von Willebrand factor type A C-terminal domain MG1 PF17790.1 OQR81947.1 - 0.038 14.4 0.1 1.6 9.2 0.1 2.2 1 1 1 2 2 2 0 Macroglobulin domain MG1 Ank_2 PF12796.7 OQR81948.1 - 3.1e-13 50.1 0.1 1.2e-12 48.2 0.1 1.8 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQR81948.1 - 4.1e-13 49.6 0.1 3e-09 37.2 0.0 2.1 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 OQR81948.1 - 5.2e-13 48.8 0.0 6.2e-08 32.8 0.0 3.1 3 0 0 3 3 3 3 Ankyrin repeat Ank_3 PF13606.6 OQR81948.1 - 3.4e-11 42.3 0.0 9.9e-05 22.5 0.0 3.2 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 OQR81948.1 - 7e-09 35.8 0.1 1.3e-05 25.3 0.1 2.6 1 1 2 3 3 3 2 Ankyrin repeats (many copies) AAA_6 PF12774.7 OQR81950.1 - 4.6e-151 502.4 0.4 5.6e-150 498.8 0.0 2.7 3 0 0 3 3 2 1 Hydrolytic ATP binding site of dynein motor region AAA_8 PF12780.7 OQR81950.1 - 2.4e-95 318.8 0.0 5.7e-95 317.6 0.0 1.6 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 AAA_9 PF12781.7 OQR81950.1 - 1.2e-86 289.4 2.3 3.7e-86 287.8 2.3 1.9 1 0 0 1 1 1 1 ATP-binding dynein motor region Dynein_C PF18199.1 OQR81950.1 - 2.2e-83 280.0 0.1 1e-82 277.8 0.0 2.3 3 0 0 3 3 3 1 Dynein heavy chain C-terminal domain AAA_7 PF12775.7 OQR81950.1 - 6.6e-73 244.1 1.0 2.7e-67 225.8 0.0 3.6 3 0 0 3 3 3 2 P-loop containing dynein motor region MT PF12777.7 OQR81950.1 - 2.2e-55 188.1 9.8 4.3e-55 187.1 9.8 1.4 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_lid_11 PF18198.1 OQR81950.1 - 1e-54 184.8 0.0 2.4e-54 183.6 0.0 1.7 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 OQR81950.1 - 1.1e-41 141.7 0.0 1.6e-40 137.9 0.0 3.0 4 0 0 4 4 2 1 Dynein heavy chain region D6 P-loop domain DHC_N2 PF08393.13 OQR81950.1 - 1.3e-26 93.7 0.1 1.3e-26 93.7 0.1 3.4 3 0 0 3 3 3 1 Dynein heavy chain, N-terminal region 2 Dynein_AAA_lid PF17852.1 OQR81950.1 - 6.6e-23 81.2 1.5 1.9e-22 79.8 0.1 2.7 2 0 0 2 2 1 1 Dynein heavy chain AAA lid domain AAA_5 PF07728.14 OQR81950.1 - 1.9e-22 79.7 0.0 4.2e-07 30.0 0.0 5.1 4 1 0 4 4 4 4 AAA domain (dynein-related subfamily) AAA_lid_1 PF17857.1 OQR81950.1 - 1.3e-13 51.0 0.0 6.5e-13 48.7 0.0 2.3 2 0 0 2 2 1 1 AAA+ lid domain AAA_22 PF13401.6 OQR81950.1 - 1.1e-12 48.5 1.5 0.00019 21.7 0.0 6.0 6 1 0 6 6 5 2 AAA domain AAA PF00004.29 OQR81950.1 - 1.8e-09 38.2 0.8 0.064 13.7 0.0 5.9 6 0 0 6 6 5 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 OQR81950.1 - 2.8e-06 27.8 7.1 0.84 10.0 0.0 5.8 6 1 1 7 7 6 2 AAA ATPase domain RNA_helicase PF00910.22 OQR81950.1 - 0.00073 19.9 0.0 8 6.9 0.0 3.9 3 0 0 3 3 3 0 RNA helicase Rad17 PF03215.15 OQR81950.1 - 0.00073 19.5 0.2 3.2 7.6 0.0 3.7 3 0 0 3 3 3 1 Rad17 P-loop domain AAA_30 PF13604.6 OQR81950.1 - 0.00085 19.1 1.2 2.7 7.7 0.0 3.7 3 0 0 3 3 3 1 AAA domain Sigma54_activat PF00158.26 OQR81950.1 - 0.0011 18.8 0.1 0.59 9.8 0.0 3.1 3 0 0 3 3 3 1 Sigma-54 interaction domain AAA_18 PF13238.6 OQR81950.1 - 0.0011 19.5 0.0 0.25 11.9 0.0 3.6 3 0 0 3 3 3 1 AAA domain RsgA_GTPase PF03193.16 OQR81950.1 - 0.0049 16.8 0.4 0.17 11.7 0.0 3.1 3 0 0 3 3 2 1 RsgA GTPase T2SSE PF00437.20 OQR81950.1 - 0.0084 15.2 0.4 1.8 7.6 0.0 3.0 3 0 0 3 3 3 1 Type II/IV secretion system protein AAA_33 PF13671.6 OQR81950.1 - 0.014 15.5 2.0 22 5.2 0.0 4.1 4 0 0 4 4 3 0 AAA domain ADIP PF11559.8 OQR81950.1 - 0.017 15.2 4.3 0.069 13.2 4.3 2.0 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding ABC_tran PF00005.27 OQR81950.1 - 0.018 15.5 0.0 0.24 11.9 0.0 2.9 2 0 0 2 2 2 0 ABC transporter AAA_19 PF13245.6 OQR81950.1 - 0.025 14.9 1.1 79 3.6 0.0 4.3 4 0 0 4 4 4 0 AAA domain DUF853 PF05872.12 OQR81950.1 - 0.039 12.5 0.8 3.5 6.1 0.0 3.0 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF853) ATP-synt_ab PF00006.25 OQR81950.1 - 0.11 12.1 0.0 0.76 9.4 0.0 2.5 2 1 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain DUF4201 PF13870.6 OQR81950.1 - 1.3 8.7 8.9 0.13 11.9 3.3 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4201) Guanylate_cyc PF00211.20 OQR81952.1 - 4.2e-10 39.5 0.0 2.4e-09 37.1 0.0 2.0 1 1 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain TPR_2 PF07719.17 OQR81952.1 - 0.0057 16.7 0.0 0.015 15.4 0.0 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat EGF_2 PF07974.13 OQR81955.1 - 7.4e-16 58.2 116.8 1.9e-05 25.0 5.8 10.5 11 0 0 11 11 11 7 EGF-like domain Laminin_EGF PF00053.24 OQR81955.1 - 0.007 16.5 4.4 0.007 16.5 4.4 8.5 8 2 0 8 8 8 5 Laminin EGF domain EGF PF00008.27 OQR81955.1 - 0.014 15.7 8.0 0.014 15.7 8.0 10.4 11 0 0 11 11 11 0 EGF-like domain Histone PF00125.24 OQR81956.1 - 8.8e-54 181.4 1.2 9.8e-54 181.2 1.2 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 PAF PF15715.5 OQR81956.1 - 0.00038 21.0 2.1 0.00048 20.7 2.1 1.1 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CENP-T_C PF15511.6 OQR81956.1 - 0.0009 19.3 0.3 0.0015 18.6 0.0 1.5 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 OQR81956.1 - 0.00091 19.6 0.0 0.0014 19.0 0.0 1.2 1 0 0 1 1 1 1 CENP-S protein CBFD_NFYB_HMF PF00808.23 OQR81956.1 - 0.023 14.9 0.0 0.046 14.0 0.0 1.5 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 OQR81956.1 - 0.033 14.3 0.1 0.059 13.4 0.0 1.5 2 0 0 2 2 2 0 Transcription initiation factor IID, 31kD subunit PFK PF00365.20 OQR81957.1 - 2.3e-56 191.2 0.2 2.9e-56 190.9 0.2 1.1 1 0 0 1 1 1 1 Phosphofructokinase DAGK_cat PF00781.24 OQR81957.1 - 0.004 16.8 0.1 0.0095 15.6 0.1 1.6 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain NAD_kinase PF01513.21 OQR81957.1 - 0.045 12.9 0.1 0.068 12.4 0.1 1.2 1 0 0 1 1 1 0 ATP-NAD kinase PhoLip_ATPase_C PF16212.5 OQR81958.1 - 8.9e-64 215.6 19.2 8.9e-64 215.6 19.2 2.5 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 OQR81958.1 - 2.3e-21 75.2 1.3 2.3e-21 75.2 1.3 2.3 2 0 0 2 2 2 1 Phospholipid-translocating ATPase N-terminal Cation_ATPase PF13246.6 OQR81958.1 - 1.5e-10 41.0 0.0 1.8e-09 37.6 0.0 2.2 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 OQR81958.1 - 4.6e-10 40.1 1.1 3.3e-06 27.5 0.2 3.1 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 OQR81958.1 - 2e-06 27.5 0.0 6.4e-06 25.8 0.0 1.9 1 1 0 1 1 1 1 E1-E2 ATPase Hydrolase_3 PF08282.12 OQR81958.1 - 0.0015 18.4 0.1 0.0035 17.1 0.0 1.6 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HA PF03457.14 OQR81962.1 - 1.4e-42 143.8 3.0 2.5e-12 46.9 0.1 5.1 5 0 0 5 5 5 4 Helicase associated domain Nbl1_Borealin_N PF10444.9 OQR81962.1 - 0.17 11.6 0.2 9.8 5.9 0.0 3.0 2 0 0 2 2 2 0 Nbl1 / Borealin N terminal TPR_2 PF07719.17 OQR81963.1 - 1.9e-07 30.7 0.7 0.00011 22.0 0.0 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.28 OQR81963.1 - 1.6e-06 27.6 2.1 5.2e-05 22.9 0.2 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 OQR81963.1 - 0.0004 20.4 0.9 0.009 16.2 0.2 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.6 OQR81963.1 - 0.0022 18.4 0.0 0.0064 17.0 0.0 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_9 PF13371.6 OQR81963.1 - 0.0029 17.7 0.1 0.041 14.0 0.0 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat ANAPC3 PF12895.7 OQR81963.1 - 0.013 15.7 0.2 0.043 14.0 0.2 1.8 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.6 OQR81963.1 - 0.049 14.3 0.1 0.63 10.7 0.0 2.7 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.6 OQR81963.1 - 0.094 13.4 0.2 1.9 9.3 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_11 PF13414.6 OQR81963.1 - 0.099 12.3 0.7 0.31 10.8 0.0 2.1 2 0 0 2 2 2 0 TPR repeat DUF2754 PF10953.8 OQR81963.1 - 1.6 9.0 4.5 3.7 7.9 1.1 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF2754) DUF3995 PF13160.6 OQR81963.1 - 4.5 7.6 9.1 0.42 11.0 0.7 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF3995) Podoplanin PF05808.11 OQR81966.1 - 0.00034 20.7 0.8 0.00062 19.9 0.8 1.4 1 0 0 1 1 1 1 Podoplanin SKG6 PF08693.10 OQR81966.1 - 0.00075 18.8 2.2 0.0013 18.0 2.2 1.4 1 0 0 1 1 1 1 Transmembrane alpha-helix domain LRR_8 PF13855.6 OQR81966.1 - 0.00094 18.9 1.9 0.0056 16.4 1.9 2.3 1 1 0 1 1 1 1 Leucine rich repeat LRR_4 PF12799.7 OQR81966.1 - 0.00094 19.5 9.6 0.34 11.4 0.5 3.7 1 1 3 4 4 4 2 Leucine Rich repeats (2 copies) TMEM154 PF15102.6 OQR81966.1 - 0.0046 16.9 0.1 0.0076 16.2 0.1 1.3 1 0 0 1 1 1 1 TMEM154 protein family Protocadherin PF08374.11 OQR81966.1 - 0.0068 16.4 0.0 0.011 15.7 0.0 1.3 1 0 0 1 1 1 1 Protocadherin DUF4064 PF13273.6 OQR81966.1 - 0.012 15.9 0.0 0.032 14.5 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF4064) DUF4366 PF14283.6 OQR81966.1 - 0.055 13.5 0.0 0.091 12.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) Mid2 PF04478.12 OQR81966.1 - 0.058 13.2 0.2 0.058 13.2 0.2 1.7 2 0 0 2 2 2 0 Mid2 like cell wall stress sensor NICE-1 PF15845.5 OQR81966.1 - 0.097 13.5 5.4 1.5 9.7 0.0 2.8 2 1 1 3 3 3 0 Cysteine-rich C-terminal 1 family EphA2_TM PF14575.6 OQR81966.1 - 0.15 13.0 0.0 0.3 12.0 0.0 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain MSA-2c PF12238.8 OQR81966.1 - 0.21 11.5 3.2 0.34 10.9 3.2 1.3 1 0 0 1 1 1 0 Merozoite surface antigen 2c Pkinase_Tyr PF07714.17 OQR81967.1 - 1.3e-44 152.4 0.0 2.4e-44 151.6 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OQR81967.1 - 1.2e-43 149.4 0.0 1.6e-43 149.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain LRR_4 PF12799.7 OQR81967.1 - 1.6e-05 25.2 17.1 0.039 14.4 1.2 5.0 3 2 2 5 5 5 3 Leucine Rich repeats (2 copies) FNIP PF05725.12 OQR81967.1 - 0.00087 19.4 4.6 1.8 8.8 0.1 3.6 3 0 0 3 3 3 2 FNIP Repeat Pkinase_fungal PF17667.1 OQR81967.1 - 0.0027 16.6 0.0 0.0039 16.0 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase LRR_8 PF13855.6 OQR81967.1 - 0.0032 17.2 6.2 0.026 14.3 1.6 3.1 2 1 2 4 4 4 3 Leucine rich repeat SKG6 PF08693.10 OQR81967.1 - 0.061 12.7 5.4 0.18 11.2 5.4 1.8 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Protocadherin PF08374.11 OQR81967.1 - 0.086 12.8 0.0 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 Protocadherin LRR_6 PF13516.6 OQR81967.1 - 6.8 7.0 6.4 35 4.8 0.0 4.5 5 0 0 5 5 5 0 Leucine Rich repeat Pkinase PF00069.25 OQR81968.1 - 3.8e-19 69.1 0.0 1.4e-18 67.2 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQR81968.1 - 2e-14 53.5 0.0 9.9e-14 51.2 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase DUF1617 PF07761.12 OQR81968.1 - 0.01 15.9 0.1 0.015 15.4 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1617) Haspin_kinase PF12330.8 OQR81968.1 - 0.14 11.0 0.0 0.2 10.6 0.0 1.1 1 0 0 1 1 1 0 Haspin like kinase domain B2-adapt-app_C PF09066.10 OQR81971.1 - 2.6e-16 59.7 0.4 3.3e-08 33.6 0.0 3.3 2 1 0 2 2 2 2 Beta2-adaptin appendage, C-terminal sub-domain FHA PF00498.26 OQR81971.1 - 1.1e-15 57.7 0.0 2.2e-15 56.8 0.0 1.5 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 OQR81971.1 - 6.3e-05 23.2 0.0 0.00016 21.9 0.0 1.6 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain Tautomerase PF01361.21 OQR81971.1 - 0.066 13.1 0.4 1.6 8.7 0.0 2.5 2 0 0 2 2 2 0 Tautomerase enzyme IQ PF00612.27 OQR81972.1 - 1.7e-06 27.3 141.5 0.013 15.2 1.2 20.0 19 1 2 21 21 21 10 IQ calmodulin-binding motif zf-B_box PF00643.24 OQR81972.1 - 0.00011 22.3 4.7 0.00011 22.3 4.7 5.6 5 1 0 5 5 5 3 B-box zinc finger TetR_C_6 PF13977.6 OQR81972.1 - 0.00021 21.5 0.3 0.00093 19.4 0.3 2.1 1 0 0 1 1 1 1 BetI-type transcriptional repressor, C-terminal DUF2564 PF10819.8 OQR81972.1 - 0.11 12.9 0.1 0.37 11.2 0.1 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2564) DUF2570 PF10828.8 OQR81972.1 - 1 9.2 8.9 0.027 14.3 0.5 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2570) Calx-beta PF03160.14 OQR81973.1 - 1.2e-33 115.2 6.5 5.6e-06 26.5 0.0 11.1 12 0 0 12 12 12 9 Calx-beta domain Cellulase PF00150.18 OQR81974.1 - 6.2e-22 78.3 12.2 8.8e-22 77.8 12.2 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_2_C PF02836.17 OQR81974.1 - 0.0036 16.5 0.2 0.006 15.7 0.2 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain adh_short_C2 PF13561.6 OQR81975.1 - 1.8e-47 161.8 0.0 2.2e-47 161.6 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OQR81975.1 - 9e-47 159.1 0.1 1.1e-46 158.8 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OQR81975.1 - 4.7e-11 42.9 0.6 9.5e-11 41.9 0.6 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 OQR81975.1 - 0.00021 20.8 0.1 0.00034 20.2 0.1 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 OQR81975.1 - 0.0016 17.5 0.0 0.0065 15.5 0.0 1.8 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Sacchrp_dh_NADP PF03435.18 OQR81975.1 - 0.0029 17.9 0.1 0.0057 16.9 0.1 1.5 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_4 PF07993.12 OQR81975.1 - 0.032 13.4 0.3 0.23 10.6 0.3 2.0 1 1 0 1 1 1 0 Male sterility protein ADH_zinc_N PF00107.26 OQR81975.1 - 0.1 12.6 0.0 0.23 11.4 0.0 1.6 1 0 0 1 1 1 0 Zinc-binding dehydrogenase UQ_con PF00179.26 OQR81976.1 - 1.4e-43 147.9 0.1 1.6e-43 147.7 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 OQR81976.1 - 0.055 13.2 0.0 0.064 13.0 0.0 1.3 1 0 0 1 1 1 0 Prokaryotic E2 family B Baculo_LEF-11 PF06385.12 OQR81977.1 - 0.14 12.7 0.0 5 7.7 0.0 2.5 1 1 1 2 2 2 0 Baculovirus LEF-11 protein GATase_6 PF13522.6 OQR81978.1 - 4e-20 72.4 0.3 5.7e-20 71.9 0.3 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.6 OQR81978.1 - 5.2e-14 52.2 0.0 8.4e-14 51.5 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.6 OQR81978.1 - 8.3e-05 21.6 0.1 9.7e-05 21.4 0.1 1.2 1 0 0 1 1 1 1 Glutamine amidotransferases class-II UCH PF00443.29 OQR81979.1 - 1.3e-18 67.5 0.0 2.4e-18 66.6 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 OQR81979.1 - 2.9e-12 46.8 0.1 4.4e-12 46.2 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-CCCH PF00642.24 OQR81979.1 - 1.9e-06 27.6 1.6 4.6e-06 26.4 1.6 1.7 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 OQR81979.1 - 5.4e-06 26.3 4.0 1.8e-05 24.6 4.0 2.0 1 0 0 1 1 1 1 Zinc finger domain Torus PF16131.5 OQR81979.1 - 0.00055 20.6 1.9 0.0013 19.4 1.9 1.6 1 0 0 1 1 1 1 Torus domain zf-CCHC_2 PF13696.6 OQR81979.1 - 0.001 18.8 4.2 0.0027 17.5 4.2 1.8 1 0 0 1 1 1 1 Zinc knuckle zf-CCCH_4 PF18044.1 OQR81979.1 - 0.0025 17.5 2.6 0.0025 17.5 2.6 2.5 2 0 0 2 2 2 1 CCCH-type zinc finger zf-CCCH_2 PF14608.6 OQR81979.1 - 0.0029 18.0 0.9 0.0029 18.0 0.9 3.2 4 0 0 4 4 4 1 RNA-binding, Nab2-type zinc finger zf-CCHC PF00098.23 OQR81979.1 - 0.21 11.7 4.5 0.66 10.2 4.5 1.9 1 0 0 1 1 1 0 Zinc knuckle EF-hand_7 PF13499.6 OQR81980.1 - 7e-12 45.6 5.6 0.0025 18.2 0.8 3.8 3 0 0 3 3 3 3 EF-hand domain pair EF-hand_1 PF00036.32 OQR81980.1 - 2.1e-09 36.3 4.4 0.0059 16.1 1.6 4.9 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.6 OQR81980.1 - 2.7e-09 36.2 3.7 0.018 14.9 0.3 4.9 4 0 0 4 4 4 3 EF-hand domain EF-hand_5 PF13202.6 OQR81980.1 - 3.4e-06 26.3 5.5 0.0018 17.7 0.5 3.6 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.6 OQR81980.1 - 9.3e-06 25.4 2.7 0.018 14.9 0.6 4.4 4 0 0 4 4 4 1 EF-hand domain pair zf-HC5HC2H_2 PF13832.6 OQR81981.1 - 2e-18 66.6 11.7 2e-18 66.6 11.7 2.5 2 0 0 2 2 2 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 OQR81981.1 - 2.9e-14 53.1 8.2 2.9e-14 53.1 8.2 3.3 2 1 1 3 3 3 1 PHD-like zinc-binding domain PHD_2 PF13831.6 OQR81981.1 - 9.4e-09 34.7 5.4 9.4e-09 34.7 5.4 3.8 4 0 0 4 4 4 1 PHD-finger PHD PF00628.29 OQR81981.1 - 1.1e-08 34.8 7.8 1.1e-08 34.8 7.8 3.8 3 1 0 3 3 3 2 PHD-finger PhnA_Zn_Ribbon PF08274.12 OQR81981.1 - 0.0049 16.8 2.1 0.0049 16.8 2.1 2.8 4 0 0 4 4 4 1 PhnA Zinc-Ribbon Prok-RING_1 PF14446.6 OQR81981.1 - 0.014 15.3 3.5 0.014 15.3 3.5 3.6 3 0 0 3 3 3 0 Prokaryotic RING finger family 1 DAGAT PF03982.13 OQR81982.1 - 1.1e-51 175.6 0.0 1.3e-51 175.2 0.0 1.1 1 0 0 1 1 1 1 Diacylglycerol acyltransferase Dexa_ind PF15198.6 OQR81982.1 - 0.52 10.5 4.4 0.99 9.6 4.4 1.4 1 0 0 1 1 1 0 Dexamethasone-induced NMO PF03060.15 OQR81983.1 - 7.3e-65 219.5 0.2 8.6e-65 219.3 0.2 1.0 1 0 0 1 1 1 1 Nitronate monooxygenase FMN_dh PF01070.18 OQR81983.1 - 1.2e-09 37.7 0.6 2.5e-09 36.6 0.6 1.4 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.25 OQR81983.1 - 8.8e-09 34.8 5.5 1.8e-06 27.2 3.4 2.4 2 0 0 2 2 2 2 IMP dehydrogenase / GMP reductase domain His_biosynth PF00977.21 OQR81983.1 - 5.8e-05 22.7 0.3 0.00012 21.7 0.0 1.6 2 0 0 2 2 2 1 Histidine biosynthesis protein DHO_dh PF01180.21 OQR81983.1 - 0.00048 19.4 0.3 0.00082 18.7 0.3 1.4 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase DUF561 PF04481.12 OQR81983.1 - 0.00075 18.7 0.1 0.0012 18.0 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF561) Glu_synthase PF01645.17 OQR81983.1 - 0.0031 16.7 0.4 0.0047 16.1 0.4 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase Dus PF01207.17 OQR81983.1 - 0.0038 16.4 0.0 0.0057 15.8 0.0 1.3 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) G3P_antiterm PF04309.12 OQR81983.1 - 0.012 15.0 0.2 0.061 12.7 0.1 2.0 2 0 0 2 2 2 0 Glycerol-3-phosphate responsive antiterminator ThiG PF05690.14 OQR81983.1 - 0.045 13.1 1.3 0.077 12.3 1.3 1.4 1 0 0 1 1 1 0 Thiazole biosynthesis protein ThiG TMP-TENI PF02581.17 OQR81983.1 - 0.075 12.4 0.9 0.17 11.2 0.9 1.7 1 1 0 1 1 1 0 Thiamine monophosphate synthase Exo_endo_phos PF03372.23 OQR81984.1 - 4.2e-13 49.4 0.5 8.9e-13 48.3 0.5 1.6 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Ank_2 PF12796.7 OQR81985.1 - 7.7e-152 494.3 75.3 1e-16 61.2 0.1 14.2 2 2 12 16 16 16 16 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQR81985.1 - 2.2e-112 366.1 42.9 8.4e-11 42.2 1.3 19.2 11 7 10 21 21 21 19 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQR81985.1 - 4.6e-97 306.1 57.1 4.2e-05 23.6 0.0 27.2 27 0 0 27 27 27 21 Ankyrin repeat Ank_5 PF13857.6 OQR81985.1 - 6.7e-92 300.4 54.9 1e-09 38.4 0.9 23.1 6 4 19 26 26 26 24 Ankyrin repeats (many copies) Ank PF00023.30 OQR81985.1 - 3.4e-78 254.9 68.7 0.0013 19.1 0.0 26.8 27 1 0 27 27 27 21 Ankyrin repeat Plasmid_RAQPRD PF09686.10 OQR81985.1 - 0.043 14.0 0.0 0.13 12.5 0.0 1.8 1 0 0 1 1 1 0 Plasmid protein of unknown function (Plasmid_RAQPRD) Peptidase_M16 PF00675.20 OQR81985.1 - 0.099 12.6 0.0 0.49 10.4 0.1 2.2 2 0 0 2 2 2 0 Insulinase (Peptidase family M16) WD40 PF00400.32 OQR81986.1 - 7.7e-45 150.0 18.4 1.6e-07 31.9 0.1 12.1 13 0 0 13 13 12 6 WD domain, G-beta repeat Utp12 PF04003.12 OQR81986.1 - 1.4e-22 80.0 2.4 2.4e-22 79.3 2.4 1.4 1 0 0 1 1 1 1 Dip2/Utp12 Family ANAPC4_WD40 PF12894.7 OQR81986.1 - 1e-21 77.0 0.0 0.00055 20.2 0.0 8.5 2 2 6 9 9 9 6 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 OQR81986.1 - 2.1e-09 36.8 0.6 0.62 9.0 0.0 6.3 3 3 2 5 5 5 3 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 OQR81986.1 - 1.3e-05 25.2 0.0 9.7 6.0 0.0 5.0 3 2 2 5 5 5 1 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 OQR81986.1 - 2.7e-05 23.0 1.3 0.083 11.5 0.2 3.5 2 1 1 4 4 4 2 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.16 OQR81986.1 - 0.0012 17.4 0.2 4 5.9 0.1 3.3 2 1 1 3 3 3 2 Cytochrome D1 heme domain PD40 PF07676.12 OQR81986.1 - 0.0076 16.2 7.2 14 5.8 0.1 6.5 8 0 0 8 8 8 1 WD40-like Beta Propeller Repeat DUF1513 PF07433.11 OQR81986.1 - 0.0083 15.2 0.1 0.57 9.2 0.0 3.3 4 0 0 4 4 4 1 Protein of unknown function (DUF1513) WD40_like PF17005.5 OQR81986.1 - 0.011 15.1 0.0 0.094 12.0 0.0 2.5 3 0 0 3 3 3 0 WD40-like domain Hira PF07569.11 OQR81986.1 - 0.047 13.4 0.2 1.7 8.3 0.0 2.9 3 1 0 3 3 3 0 TUP1-like enhancer of split Proteasome_A_N PF10584.9 OQR81986.1 - 0.4 10.4 4.2 4 7.2 0.0 4.0 4 0 0 4 4 3 0 Proteasome subunit A N-terminal signature fn3 PF00041.21 OQR81987.1 - 1.6e-07 31.5 0.0 3.1e-07 30.6 0.0 1.4 1 0 0 1 1 1 1 Fibronectin type III domain Ank_5 PF13857.6 OQR81987.1 - 2.6e-05 24.4 0.0 7.2e-05 23.0 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQR81987.1 - 0.0001 22.4 0.1 0.00048 20.4 0.0 2.1 2 0 0 2 2 2 1 Ankyrin repeat Ank_2 PF12796.7 OQR81987.1 - 0.00012 22.6 0.0 0.00022 21.7 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQR81987.1 - 0.0014 19.2 0.0 0.0045 17.5 0.0 1.9 1 0 0 1 1 1 1 Ankyrin repeats (many copies) DUF4675 PF15720.5 OQR81987.1 - 0.022 14.6 0.0 0.053 13.3 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4675) Ank PF00023.30 OQR81987.1 - 0.057 13.9 0.1 0.21 12.1 0.0 2.0 2 0 0 2 2 2 0 Ankyrin repeat FYVE PF01363.21 OQR81988.1 - 1.7e-05 24.9 13.4 4.4e-05 23.5 13.4 1.7 1 0 0 1 1 1 1 FYVE zinc finger GAF PF01590.26 OQR81988.1 - 0.00072 20.2 0.0 0.0026 18.4 0.0 2.0 1 0 0 1 1 1 1 GAF domain zf-AN1 PF01428.16 OQR81988.1 - 1.4 9.1 5.8 5.1 7.3 5.8 2.0 1 0 0 1 1 1 0 AN1-like Zinc finger FYVE_2 PF02318.16 OQR81988.1 - 5.4 7.2 16.0 0.097 12.9 8.1 2.1 2 0 0 2 2 2 0 FYVE-type zinc finger Laminin_B PF00052.18 OQR81989.1 - 8.7e-13 48.3 0.0 4e-12 46.2 0.0 2.0 2 0 0 2 2 2 1 Laminin B (Domain IV) RdRP_4 PF02123.16 OQR81989.1 - 0.21 10.4 0.0 0.29 9.9 0.0 1.1 1 0 0 1 1 1 0 Viral RNA-directed RNA-polymerase Big_9 PF17963.1 OQR81989.1 - 0.55 11.0 4.6 4.5 8.1 2.8 2.8 2 1 0 2 2 2 0 Bacterial Ig domain KH_1 PF00013.29 OQR81990.1 - 8.6e-17 60.7 0.3 1.2e-07 31.4 0.0 4.8 4 1 0 4 4 4 3 KH domain RNA_pol_Rpc34 PF05158.12 OQR81991.1 - 3.5e-67 227.2 1.5 4.1e-48 164.5 0.4 2.0 1 1 1 2 2 2 2 RNA polymerase Rpc34 subunit HMD PF03201.16 OQR81991.1 - 0.044 14.0 0.1 0.69 10.2 0.0 2.3 2 0 0 2 2 2 0 H2-forming N5,N10-methylene-tetrahydromethanopterin dehydrogenase B-block_TFIIIC PF04182.12 OQR81991.1 - 0.058 13.5 0.9 0.11 12.7 0.2 1.8 2 0 0 2 2 2 0 B-block binding subunit of TFIIIC TrmB PF01978.19 OQR81991.1 - 0.15 11.9 0.4 2.4 8.1 0.1 2.3 2 0 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB Dynein_light PF01221.18 OQR81992.1 - 9.5e-14 51.5 0.1 1.1e-13 51.3 0.1 1.1 1 0 0 1 1 1 1 Dynein light chain type 1 FdsD PF11390.8 OQR81992.1 - 0.18 12.2 0.1 0.73 10.2 0.1 2.0 2 0 0 2 2 2 0 NADH-dependant formate dehydrogenase delta subunit FdsD WD40 PF00400.32 OQR81993.1 - 3.5e-57 189.1 9.8 3.2e-09 37.2 0.1 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OQR81993.1 - 1.3e-23 83.1 0.1 0.00084 19.6 0.1 6.1 2 1 4 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 OQR81993.1 - 4.5e-09 35.5 7.0 0.054 12.1 0.1 5.4 2 1 4 6 6 6 4 Nucleoporin Nup120/160 eIF2A PF08662.11 OQR81993.1 - 1.3e-08 34.9 0.0 0.00027 20.9 0.0 3.5 1 1 3 4 4 4 2 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 OQR81993.1 - 2.5e-08 33.3 0.2 0.17 10.8 0.0 4.9 1 1 4 5 5 5 2 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 OQR81993.1 - 2.9e-07 30.1 0.0 0.0044 16.4 0.0 4.0 2 1 2 4 4 4 2 WD40-like domain Nbas_N PF15492.6 OQR81993.1 - 0.00059 19.2 0.3 1.4 8.2 0.1 3.6 1 1 3 4 4 4 2 Neuroblastoma-amplified sequence, N terminal Cytochrom_D1 PF02239.16 OQR81993.1 - 0.0012 17.4 0.2 0.29 9.6 0.1 2.8 1 1 3 4 4 4 1 Cytochrome D1 heme domain Itfg2 PF15907.5 OQR81993.1 - 0.0063 15.6 0.0 0.059 12.4 0.0 2.0 2 0 0 2 2 2 1 Integrin-alpha FG-GAP repeat-containing protein 2 PHTB1_N PF14727.6 OQR81993.1 - 0.024 14.0 0.0 0.083 12.2 0.0 1.8 2 0 0 2 2 2 0 PTHB1 N-terminus Nucleoporin_N PF08801.11 OQR81993.1 - 0.042 12.6 0.6 4 6.1 0.1 3.2 2 1 1 4 4 4 0 Nup133 N terminal like CbiG_N PF11760.8 OQR81993.1 - 0.1 12.6 0.0 6.8 6.8 0.1 2.7 3 0 0 3 3 3 0 Cobalamin synthesis G N-terminal Rav1p_C PF12234.8 OQR81993.1 - 0.16 10.3 0.2 0.96 7.8 0.3 1.9 1 1 0 2 2 2 0 RAVE protein 1 C terminal DAGAT PF03982.13 OQR81994.1 - 8.2e-53 179.2 0.0 1e-52 178.9 0.0 1.1 1 0 0 1 1 1 1 Diacylglycerol acyltransferase GAF PF01590.26 OQR81995.1 - 5.3e-05 23.9 0.0 0.00019 22.0 0.0 1.9 2 0 0 2 2 2 1 GAF domain FYVE PF01363.21 OQR81995.1 - 0.031 14.4 8.9 0.031 14.4 8.9 3.0 2 1 0 2 2 2 0 FYVE zinc finger IstB_IS21 PF01695.17 OQR81997.1 - 0.015 15.0 0.1 0.12 12.1 0.0 2.0 2 0 0 2 2 2 0 IstB-like ATP binding protein Syntaxin-6_N PF09177.11 OQR81997.1 - 0.56 10.8 3.4 5.8 7.5 1.9 3.0 1 1 0 2 2 2 0 Syntaxin 6, N-terminal Amidohydro_2 PF04909.14 OQR81998.1 - 4.8e-23 82.4 0.2 6.6e-23 81.9 0.2 1.2 1 0 0 1 1 1 1 Amidohydrolase HTH_5 PF01022.20 OQR81998.1 - 0.047 13.6 0.2 0.82 9.6 0.0 2.7 3 0 0 3 3 3 0 Bacterial regulatory protein, arsR family DUF2259 PF10016.9 OQR82000.1 - 1.1 9.1 8.0 1.3 8.9 0.7 3.2 2 1 0 2 2 2 0 Predicted secreted protein (DUF2259) HAP1_N PF04849.13 OQR82000.1 - 2.6 7.2 54.4 6.1 5.9 40.2 3.3 2 1 0 2 2 2 0 HAP1 N-terminal conserved region Sec10 PF07393.11 OQR82001.1 - 2.2e-79 267.7 6.8 3.8e-78 263.6 6.8 2.0 1 1 0 1 1 1 1 Exocyst complex component Sec10 DUF4507 PF14964.6 OQR82001.1 - 0.0007 18.6 3.5 0.0013 17.8 0.8 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4507) SARA PF11409.8 OQR82001.1 - 0.24 11.6 1.1 0.72 10.1 1.1 1.8 1 0 0 1 1 1 0 Smad anchor for receptor activation (SARA) DUF592 PF04574.13 OQR82001.1 - 1.4 8.7 5.7 0.31 10.8 0.4 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF592) Cyclin_N PF00134.23 OQR82002.1 - 7.1e-11 41.9 1.4 7.1e-11 41.9 1.4 2.1 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 OQR82002.1 - 0.0033 17.5 0.7 0.087 12.9 0.4 2.3 2 0 0 2 2 2 1 Cyclin, C-terminal domain DUF2163 PF09931.9 OQR82002.1 - 0.048 13.9 0.1 0.08 13.2 0.1 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2163) TPR_2 PF07719.17 OQR82003.1 - 1e-11 44.0 11.7 0.0013 18.7 1.9 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.28 OQR82003.1 - 1e-09 37.8 10.7 0.011 15.5 1.8 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.6 OQR82003.1 - 1.4e-06 28.8 10.8 9.9e-05 22.9 3.0 2.2 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.6 OQR82003.1 - 5.1e-06 26.7 6.8 0.013 15.7 2.0 2.8 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 OQR82003.1 - 9.3e-05 22.3 11.1 0.024 14.8 0.5 4.4 5 1 1 6 6 5 2 Tetratricopeptide repeat TPR_17 PF13431.6 OQR82003.1 - 0.00014 22.0 1.2 0.057 13.8 0.0 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.6 OQR82003.1 - 0.0002 21.0 5.6 0.024 14.3 0.3 2.4 1 1 1 2 2 2 2 TPR repeat TPR_14 PF13428.6 OQR82003.1 - 0.00036 21.1 7.9 0.2 12.6 0.2 3.3 1 1 2 3 3 3 2 Tetratricopeptide repeat DUF3856 PF12968.7 OQR82003.1 - 0.048 13.7 1.1 1.5 8.9 1.1 2.9 1 1 0 1 1 1 0 Domain of Unknown Function (DUF3856) TPR_10 PF13374.6 OQR82003.1 - 0.065 13.1 7.5 0.99 9.4 0.3 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF1353 PF07087.11 OQR82003.1 - 0.078 12.7 0.1 0.17 11.7 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1353) EF1G PF00647.19 OQR82003.1 - 0.082 13.0 0.5 0.25 11.4 0.2 1.9 1 1 1 2 2 2 0 Elongation factor 1 gamma, conserved domain TPR_9 PF13371.6 OQR82003.1 - 0.13 12.4 2.6 0.66 10.2 2.6 2.2 1 1 0 1 1 1 0 Tetratricopeptide repeat TPR_21 PF09976.9 OQR82003.1 - 0.15 11.7 6.7 0.4 10.4 6.7 1.6 1 1 0 1 1 1 0 Tetratricopeptide repeat-like domain TPR_19 PF14559.6 OQR82003.1 - 1.4 9.5 9.3 2.8 8.5 3.1 2.3 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.6 OQR82003.1 - 1.5 9.7 8.6 0.8 10.5 1.0 2.9 3 0 0 3 3 2 0 Tetratricopeptide repeat TPR_7 PF13176.6 OQR82003.1 - 2.8 8.2 5.8 23 5.3 0.3 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat DAO PF01266.24 OQR82004.1 - 3e-49 168.5 0.0 3.7e-49 168.2 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 OQR82004.1 - 2.5e-10 40.1 0.2 1.9e-05 24.0 0.1 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OQR82004.1 - 1.8e-07 31.3 0.1 5e-07 29.8 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 OQR82004.1 - 7.7e-06 24.9 0.3 0.024 13.4 0.0 2.2 2 0 0 2 2 2 2 HI0933-like protein FAD_binding_2 PF00890.24 OQR82004.1 - 1.3e-05 24.5 0.1 0.001 18.2 0.0 2.2 2 0 0 2 2 2 1 FAD binding domain Pyr_redox PF00070.27 OQR82004.1 - 3.4e-05 24.3 0.8 0.0075 16.8 0.3 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 OQR82004.1 - 0.00053 19.4 0.0 0.011 15.1 0.0 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.17 OQR82004.1 - 0.00058 19.2 0.0 0.0062 15.8 0.0 2.4 3 0 0 3 3 3 1 Thi4 family UDPG_MGDP_dh_N PF03721.14 OQR82004.1 - 0.0011 18.6 0.5 0.0022 17.6 0.5 1.5 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Amino_oxidase PF01593.24 OQR82004.1 - 0.01 15.2 0.2 2.9 7.1 0.1 2.3 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase GIDA PF01134.22 OQR82004.1 - 0.013 14.6 0.8 0.62 9.1 0.2 2.2 2 0 0 2 2 2 0 Glucose inhibited division protein A AlaDh_PNT_C PF01262.21 OQR82004.1 - 0.035 13.4 0.0 0.06 12.6 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_3 PF01494.19 OQR82004.1 - 0.067 12.4 0.4 0.13 11.4 0.4 1.4 1 0 0 1 1 1 0 FAD binding domain ApbA PF02558.16 OQR82004.1 - 0.1 12.2 0.2 0.18 11.5 0.2 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Pyr_redox_3 PF13738.6 OQR82004.1 - 0.22 10.8 0.0 2 7.6 0.0 2.3 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase CorA PF01544.18 OQR82005.1 - 8.6e-37 127.0 4.7 2.6e-29 102.5 1.9 2.3 2 0 0 2 2 2 2 CorA-like Mg2+ transporter protein APG12 PF04110.13 OQR82005.1 - 1.7e-29 102.0 0.0 4.3e-29 100.7 0.0 1.8 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 EF-hand_1 PF00036.32 OQR82005.1 - 6.5e-07 28.5 0.6 2.5e-06 26.6 0.6 2.1 1 0 0 1 1 1 1 EF hand Atg8 PF02991.16 OQR82005.1 - 8.6e-07 29.1 0.0 3.3e-06 27.2 0.0 2.1 1 1 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like EF-hand_5 PF13202.6 OQR82005.1 - 5e-06 25.8 0.3 2.5e-05 23.5 0.2 2.2 2 0 0 2 2 2 1 EF hand EF-hand_7 PF13499.6 OQR82005.1 - 2.3e-05 24.8 0.0 0.00013 22.3 0.0 2.4 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.6 OQR82005.1 - 2.4e-05 24.1 0.0 6.1e-05 22.8 0.0 1.7 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 OQR82005.1 - 8.8e-05 22.1 0.1 0.00038 20.2 0.1 2.1 1 0 0 1 1 1 1 EF-hand domain Tub PF01167.18 OQR82006.1 - 3.7e-58 197.1 0.3 6.8e-58 196.3 0.3 1.4 1 0 0 1 1 1 1 Tub family DUF3527 PF12043.8 OQR82006.1 - 0.0039 16.8 0.1 0.0039 16.8 0.1 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF3527) tRNA_synthFbeta PF17759.1 OQR82006.1 - 0.095 12.1 1.2 0.22 10.9 1.2 1.5 1 0 0 1 1 1 0 Phenylalanyl tRNA synthetase beta chain CLM domain Ank_4 PF13637.6 OQR82007.1 - 1.3e-27 95.7 9.3 6.9e-06 26.5 0.1 5.9 6 2 1 7 7 7 5 Ankyrin repeats (many copies) Ank_2 PF12796.7 OQR82007.1 - 7.1e-26 90.6 9.0 2.1e-07 31.4 0.2 5.2 2 2 4 6 6 6 5 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OQR82007.1 - 1.4e-18 66.7 10.3 0.011 16.0 0.0 8.3 2 1 7 9 9 9 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQR82007.1 - 6.7e-15 53.7 8.3 6.3 7.7 0.1 9.4 8 2 2 10 10 10 5 Ankyrin repeat DASH_Dad4 PF08650.10 OQR82007.1 - 7.3e-14 51.5 0.6 1.4e-13 50.6 0.6 1.4 1 0 0 1 1 1 1 DASH complex subunit Dad4 HA PF03457.14 OQR82007.1 - 0.0013 19.0 0.0 1.6 9.1 0.0 4.2 2 1 0 2 2 2 1 Helicase associated domain DUF5448 PF17526.2 OQR82007.1 - 0.053 13.7 0.0 0.12 12.5 0.0 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5448) DUF3322 PF11795.8 OQR82007.1 - 0.12 12.4 0.3 40 4.1 0.0 3.9 1 1 4 5 5 5 0 Uncharacterized protein conserved in bacteria N-term (DUF3322) Ank PF00023.30 OQR82007.1 - 0.22 12.0 2.1 1.2e+02 3.4 0.2 5.2 3 1 1 4 4 4 0 Ankyrin repeat TGBp3 PF02495.17 OQR82007.1 - 0.24 11.1 0.8 1.4e+02 2.3 0.0 4.4 5 0 0 5 5 5 0 Triple gene block 3 DAO PF01266.24 OQR82008.1 - 3.1e-55 188.2 0.0 3.8e-55 187.9 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 OQR82008.1 - 5.8e-10 38.9 0.0 1e-05 24.9 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OQR82008.1 - 8.1e-09 35.6 0.1 2.4e-08 34.1 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 OQR82008.1 - 3.3e-08 32.7 0.0 0.0037 16.0 0.0 2.2 2 0 0 2 2 2 2 HI0933-like protein FAD_binding_2 PF00890.24 OQR82008.1 - 1.7e-07 30.7 0.6 2.3e-06 27.0 0.6 2.1 1 1 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.27 OQR82008.1 - 4.3e-07 30.4 0.3 3.7e-05 24.2 0.3 2.8 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase UDPG_MGDP_dh_N PF03721.14 OQR82008.1 - 0.00014 21.5 0.2 0.00039 20.1 0.1 1.8 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Thi4 PF01946.17 OQR82008.1 - 0.00018 20.8 0.0 0.0023 17.2 0.0 2.3 3 0 0 3 3 3 1 Thi4 family GIDA PF01134.22 OQR82008.1 - 0.00041 19.6 0.0 0.053 12.6 0.0 2.2 2 0 0 2 2 2 1 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 OQR82008.1 - 0.00057 19.2 0.0 0.022 14.0 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 OQR82008.1 - 0.0018 17.7 0.1 0.22 10.7 0.1 2.2 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase FAD_binding_3 PF01494.19 OQR82008.1 - 0.0034 16.7 0.9 0.0067 15.7 0.3 1.7 2 0 0 2 2 2 1 FAD binding domain FAD_oxidored PF12831.7 OQR82008.1 - 0.0043 16.5 0.0 0.01 15.2 0.0 1.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase ApbA PF02558.16 OQR82008.1 - 0.017 14.8 0.3 0.041 13.5 0.3 1.6 1 1 0 1 1 1 0 Ketopantoate reductase PanE/ApbA 3HCDH_N PF02737.18 OQR82008.1 - 0.018 14.9 0.1 0.033 14.1 0.1 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 OQR82008.1 - 0.029 13.6 0.0 0.043 13.1 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Trp_halogenase PF04820.14 OQR82008.1 - 0.12 11.2 0.9 0.31 9.8 0.2 1.9 2 0 0 2 2 2 0 Tryptophan halogenase TrkA_N PF02254.18 OQR82008.1 - 0.14 12.5 0.1 0.26 11.6 0.1 1.4 1 0 0 1 1 1 0 TrkA-N domain PP2C PF00481.21 OQR82009.1 - 1.8e-41 142.5 0.0 2.3e-41 142.2 0.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 OQR82009.1 - 4.4e-06 26.5 0.0 8.2e-06 25.6 0.0 1.4 1 0 0 1 1 1 1 Protein phosphatase 2C Cyclin_N PF00134.23 OQR82010.1 - 2e-06 27.6 0.2 3.6e-06 26.7 0.2 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.11 OQR82010.1 - 3.3e-06 27.5 0.0 4.4e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 Cyclin JHY PF15261.6 OQR82011.1 - 9.3e-17 62.0 13.9 9.3e-17 62.0 13.9 2.4 2 1 0 2 2 2 1 Jhy protein DUF406 PF04175.12 OQR82011.1 - 3.9 8.0 7.1 7 7.2 0.2 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF406) LRR_4 PF12799.7 OQR82013.1 - 0.00091 19.6 3.4 3.2 8.3 1.0 3.8 3 0 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 OQR82013.1 - 0.0083 16.1 0.3 0.0083 16.1 0.3 4.5 5 0 0 5 5 5 1 Leucine Rich repeat VPS9 PF02204.18 OQR82014.1 - 6.3e-13 48.9 0.0 1.3e-12 47.8 0.0 1.6 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain C1_1 PF00130.22 OQR82014.1 - 0.028 14.3 6.2 0.07 13.0 6.2 1.6 1 1 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Prok-RING_1 PF14446.6 OQR82014.1 - 0.088 12.8 7.3 0.51 10.3 4.2 2.4 1 1 1 2 2 2 0 Prokaryotic RING finger family 1 4_1_CTD PF05902.13 OQR82014.1 - 0.089 12.9 0.3 0.33 11.1 0.3 1.9 1 1 0 1 1 1 0 4.1 protein C-terminal domain (CTD) PHD PF00628.29 OQR82014.1 - 5.1 7.1 8.2 10 6.1 8.2 1.5 1 0 0 1 1 1 0 PHD-finger zf-RING_2 PF13639.6 OQR82014.1 - 7.2 7.0 10.0 39 4.7 10.2 2.2 1 1 1 2 2 2 0 Ring finger domain RRM_1 PF00076.22 OQR82015.1 - 1.1e-61 204.5 3.5 3.8e-18 65.1 0.2 4.8 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 OQR82015.1 - 1.9e-07 30.8 1.1 0.76 9.7 0.0 4.7 3 2 0 3 3 3 3 Occluded RNA-recognition motif RRM_5 PF13893.6 OQR82015.1 - 2.2e-05 24.0 0.2 0.021 14.4 0.1 2.7 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 OQR82015.1 - 0.0033 17.4 0.1 44 4.2 0.0 4.5 5 0 0 5 5 5 1 Nup53/35/40-type RNA recognition motif PDZ PF00595.24 OQR82016.1 - 0.089 13.2 0.0 0.18 12.2 0.0 1.4 1 0 0 1 1 1 0 PDZ domain ParcG PF10274.9 OQR82017.1 - 6.3e-43 147.0 0.0 7.6e-43 146.8 0.0 1.1 1 0 0 1 1 1 1 Parkin co-regulated protein Elicitin PF00964.17 OQR82018.1 - 7e-14 51.7 9.7 2.5e-07 30.7 0.2 2.8 3 0 0 3 3 3 2 Elicitin TPR_2 PF07719.17 OQR82019.1 - 2.3e-11 42.9 23.6 0.049 13.8 1.0 8.7 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_1 PF00515.28 OQR82019.1 - 2.5e-11 42.9 16.5 0.0059 16.4 0.3 7.9 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_12 PF13424.6 OQR82019.1 - 7.5e-07 29.4 31.6 0.094 13.0 1.2 6.8 6 1 1 7 7 7 4 Tetratricopeptide repeat TPR_14 PF13428.6 OQR82019.1 - 0.00011 22.7 22.9 22 6.2 0.1 8.4 6 4 2 8 8 8 0 Tetratricopeptide repeat TPR_19 PF14559.6 OQR82019.1 - 0.0016 18.9 19.7 2.1 8.9 0.6 6.0 5 1 1 6 6 6 3 Tetratricopeptide repeat TPR_7 PF13176.6 OQR82019.1 - 0.0056 16.6 11.3 7.6 6.8 0.3 6.4 7 1 0 7 7 7 1 Tetratricopeptide repeat TPR_17 PF13431.6 OQR82019.1 - 0.023 15.1 9.9 4.8 7.8 0.1 6.5 5 2 0 5 5 5 0 Tetratricopeptide repeat ABATE PF07336.11 OQR82019.1 - 0.14 12.8 2.7 0.55 10.9 2.8 2.0 1 1 0 1 1 1 0 Putative stress-induced transcription regulator TPR_8 PF13181.6 OQR82019.1 - 1.1 9.7 0.0 1.1 9.7 0.0 6.8 9 0 0 9 9 9 0 Tetratricopeptide repeat TPR_11 PF13414.6 OQR82019.1 - 5.4 6.8 18.8 0.38 10.5 1.6 5.3 6 0 0 6 6 6 0 TPR repeat TPR_9 PF13371.6 OQR82019.1 - 5.5 7.2 15.4 0.66 10.2 1.6 5.0 5 1 0 5 5 5 0 Tetratricopeptide repeat UPF0242 PF06785.11 OQR82020.1 - 0.073 13.2 9.6 0.13 12.3 9.6 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus CT_C_D PF02682.16 OQR82020.1 - 0.074 12.8 1.9 0.14 11.8 1.8 1.5 1 1 0 1 1 1 0 Carboxyltransferase domain, subdomain C and D DUF4407 PF14362.6 OQR82020.1 - 0.2 11.0 9.1 0.36 10.1 9.1 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Mod_r PF07200.13 OQR82020.1 - 1.5 9.0 11.8 3.1 7.9 11.2 1.8 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein AKAP7_NLS PF10469.9 OQR82021.1 - 7.5e-31 107.6 0.0 1.6e-30 106.6 0.0 1.6 1 0 0 1 1 1 1 AKAP7 2'5' RNA ligase-like domain MJ1316 PF04457.12 OQR82021.1 - 1e-25 90.3 1.4 2.6e-25 88.9 1.4 1.8 1 0 0 1 1 1 1 MJ1316 RNA cyclic group end recognition domain AAA_33 PF13671.6 OQR82021.1 - 4.3e-09 36.7 0.0 1.3e-08 35.1 0.0 1.8 1 0 0 1 1 1 1 AAA domain 2_5_RNA_ligase2 PF13563.6 OQR82021.1 - 2.2e-06 27.7 0.7 0.0002 21.3 0.0 3.2 2 1 1 3 3 3 1 2'-5' RNA ligase superfamily AAA_16 PF13191.6 OQR82021.1 - 0.00028 21.3 0.0 0.0007 20.0 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain ABC_tran PF00005.27 OQR82021.1 - 0.00046 20.7 0.1 0.0012 19.3 0.0 1.7 2 0 0 2 2 1 1 ABC transporter KTI12 PF08433.10 OQR82021.1 - 0.00087 18.8 0.0 0.0021 17.6 0.0 1.7 1 1 0 1 1 1 1 Chromatin associated protein KTI12 CPT PF07931.12 OQR82021.1 - 0.0011 18.8 0.0 0.0027 17.6 0.0 1.7 1 0 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein LigT_PEase PF02834.16 OQR82021.1 - 0.0012 18.9 0.0 0.46 10.7 0.0 3.4 2 1 1 3 3 3 1 LigT like Phosphoesterase Viral_helicase1 PF01443.18 OQR82021.1 - 0.0045 16.8 0.0 0.011 15.5 0.0 1.7 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA_24 PF13479.6 OQR82021.1 - 0.012 15.3 0.0 0.031 14.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 OQR82021.1 - 0.018 14.7 0.0 0.048 13.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 OQR82021.1 - 0.031 14.8 0.0 0.073 13.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain 6PF2K PF01591.18 OQR82021.1 - 0.045 13.1 0.0 0.088 12.1 0.0 1.4 1 0 0 1 1 1 0 6-phosphofructo-2-kinase RWD PF05773.22 OQR82021.1 - 0.045 14.0 0.6 0.45 10.8 0.6 2.5 1 1 0 1 1 1 0 RWD domain Zeta_toxin PF06414.12 OQR82021.1 - 0.061 12.6 0.1 0.53 9.5 0.1 2.3 1 1 0 1 1 1 0 Zeta toxin DAP3 PF10236.9 OQR82021.1 - 0.094 11.9 0.0 0.17 11.0 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 NACHT PF05729.12 OQR82021.1 - 0.16 11.9 0.0 0.32 10.9 0.0 1.5 1 0 0 1 1 1 0 NACHT domain AAA_14 PF13173.6 OQR82021.1 - 0.18 11.9 0.0 0.34 11.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain Tat PF00539.18 OQR82021.1 - 0.99 9.6 3.2 1.7 8.8 0.4 2.3 2 0 0 2 2 2 0 Transactivating regulatory protein (Tat) Cation_ATPase_C PF00689.21 OQR82022.1 - 4e-40 137.5 0.5 4e-40 137.5 0.5 1.7 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase_3 PF08282.12 OQR82022.1 - 0.0032 17.3 0.6 0.0047 16.7 0.6 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 OQR82022.1 - 0.031 14.6 0.0 0.055 13.7 0.0 1.4 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Ost5 PF05251.12 OQR82022.1 - 0.51 10.6 6.4 0.3 11.4 3.8 2.0 2 0 0 2 2 2 0 Oligosaccharyltransferase subunit 5 Ricin_B_lectin PF00652.22 OQR82025.1 - 4.6e-06 26.9 1.4 1.3e-05 25.4 0.6 2.0 2 0 0 2 2 2 1 Ricin-type beta-trefoil lectin domain UVR PF02151.19 OQR82026.1 - 4.3e-06 26.3 18.7 4.3e-05 23.1 7.0 2.7 2 0 0 2 2 2 2 UvrB/uvrC motif F5_F8_type_C PF00754.25 OQR82026.1 - 0.00018 21.6 0.0 0.00043 20.4 0.0 1.6 1 0 0 1 1 1 1 F5/8 type C domain FlxA PF14282.6 OQR82026.1 - 0.14 12.2 4.7 0.55 10.3 0.3 3.0 2 0 0 2 2 2 0 FlxA-like protein DUF5575 PF17738.1 OQR82026.1 - 0.21 10.6 0.9 0.38 9.8 0.9 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5575) DUF4055 PF13264.6 OQR82026.1 - 0.28 11.3 1.7 0.63 10.2 1.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4055) zf-Di19 PF05605.12 OQR82026.1 - 5.8 7.3 19.1 13 6.2 5.2 3.1 1 1 2 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding Prok-RING_4 PF14447.6 OQR82026.1 - 9.6 6.2 14.4 25 4.8 1.6 3.8 3 0 0 3 3 3 0 Prokaryotic RING finger family 4 Hydrolase_3 PF08282.12 OQR82027.1 - 0.18 11.5 0.0 0.28 10.9 0.0 1.3 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase DUF4133 PF13571.6 OQR82027.1 - 0.26 11.6 3.5 2.1 8.7 0.1 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4133) Ank_2 PF12796.7 OQR82028.1 - 2.2e-30 105.1 2.2 1.4e-14 54.4 0.1 4.3 3 0 0 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQR82028.1 - 4.3e-28 97.3 4.3 1.4e-07 31.9 0.1 4.4 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQR82028.1 - 1e-24 83.9 1.7 0.00033 20.9 0.0 7.3 7 0 0 7 7 7 4 Ankyrin repeat Ank_5 PF13857.6 OQR82028.1 - 3.3e-19 68.7 4.2 7.6e-08 32.5 0.1 4.9 2 2 2 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 OQR82028.1 - 6.7e-19 67.4 5.5 2.3e-07 30.9 0.2 5.9 5 0 0 5 5 5 4 Ankyrin repeat HEAT PF02985.22 OQR82028.1 - 3e-05 23.9 10.4 3.5 8.1 0.1 8.2 8 0 0 8 8 8 1 HEAT repeat CLASP_N PF12348.8 OQR82028.1 - 0.00063 19.4 4.9 0.0078 15.8 0.1 4.0 3 1 0 3 3 3 1 CLASP N terminal IFRD PF05004.13 OQR82028.1 - 0.022 13.9 5.9 1.6 7.7 0.3 3.4 3 2 0 3 3 3 0 Interferon-related developmental regulator (IFRD) Vac14_Fab1_bd PF12755.7 OQR82028.1 - 0.072 13.7 0.0 18 6.0 0.0 4.3 4 0 0 4 4 4 0 Vacuolar 14 Fab1-binding region Clc-like PF07062.12 OQR82029.1 - 1.1 8.7 9.2 3.8 6.9 9.2 2.0 1 1 0 1 1 1 0 Clc-like SLATT_5 PF18160.1 OQR82029.1 - 7.5 5.8 7.1 19 4.5 7.1 1.6 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain family 5 VIT1 PF01988.19 OQR82030.1 - 3.6e-18 66.2 0.1 5.7e-18 65.6 0.1 1.3 1 0 0 1 1 1 1 VIT family NCE101 PF11654.8 OQR82030.1 - 0.019 14.7 1.1 0.043 13.5 0.1 2.0 2 0 0 2 2 2 0 Non-classical export protein 1 GAF_2 PF13185.6 OQR82031.1 - 1.1e-05 25.8 0.0 1.8e-05 25.1 0.0 1.4 1 0 0 1 1 1 1 GAF domain Thioredoxin PF00085.20 OQR82031.1 - 0.00016 21.6 0.0 0.00029 20.8 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin GAF PF01590.26 OQR82031.1 - 0.003 18.2 0.0 0.0047 17.6 0.0 1.3 1 0 0 1 1 1 1 GAF domain PGK PF00162.19 OQR82032.1 - 1.3e-148 495.0 2.8 1.5e-148 494.8 2.8 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase FtsJ PF01728.19 OQR82033.1 - 6.7e-51 172.9 0.0 7.5e-51 172.7 0.0 1.0 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_31 PF13847.6 OQR82033.1 - 3.3e-05 23.7 0.0 0.0092 15.8 0.0 2.1 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_23 PF13489.6 OQR82033.1 - 0.0026 17.6 0.0 0.0038 17.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain NNMT_PNMT_TEMT PF01234.17 OQR82033.1 - 0.085 12.0 0.0 8 5.6 0.0 2.1 2 0 0 2 2 2 0 NNMT/PNMT/TEMT family START PF01852.19 OQR82034.1 - 1.8e-18 66.8 0.0 2.1e-18 66.5 0.0 1.1 1 0 0 1 1 1 1 START domain DUF1826 PF08856.11 OQR82034.1 - 0.058 13.3 0.0 0.094 12.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1826) Steroid_dh PF02544.16 OQR82035.1 - 3.2e-19 69.4 0.5 5.6e-19 68.6 0.5 1.4 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase Astro_capsid_p PF12226.8 OQR82035.1 - 0.092 11.9 0.0 0.13 11.4 0.0 1.2 1 0 0 1 1 1 0 Turkey astrovirus capsid protein Mito_carr PF00153.27 OQR82036.1 - 1e-51 172.8 7.2 1.6e-17 63.2 0.0 3.9 3 1 0 3 3 3 3 Mitochondrial carrier protein tRNA-synt_1 PF00133.22 OQR82037.1 - 1e-40 139.6 0.0 2.2e-24 85.7 0.0 2.4 2 1 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.11 OQR82037.1 - 3.7e-19 68.7 0.9 2.1e-08 33.4 0.0 2.7 3 0 0 3 3 3 2 tRNA synthetases class I (M) Anticodon_1 PF08264.13 OQR82037.1 - 2.7e-12 46.9 0.0 6.5e-12 45.7 0.0 1.7 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.19 OQR82037.1 - 8.4e-07 28.6 0.0 1.8e-06 27.5 0.0 1.6 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain DDE_Tnp_4 PF13359.6 OQR82038.1 - 5.1e-05 23.0 0.0 5.5e-05 22.9 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease NAGLU PF05089.12 OQR82039.1 - 1.1e-127 425.6 10.1 3.5e-127 424.0 6.6 2.1 2 0 0 2 2 2 2 Alpha-N-acetylglucosaminidase (NAGLU) tim-barrel domain NAGLU_C PF12972.7 OQR82039.1 - 1.1e-66 225.1 2.6 1.9e-66 224.3 2.6 1.4 1 0 0 1 1 1 1 Alpha-N-acetylglucosaminidase (NAGLU) C-terminal domain NAGLU_N PF12971.7 OQR82039.1 - 1.1e-14 53.9 0.0 2.5e-14 52.8 0.0 1.6 1 0 0 1 1 1 1 Alpha-N-acetylglucosaminidase (NAGLU) N-terminal domain PARP PF00644.20 OQR82040.1 - 1.2e-11 44.6 3.9 2.5e-11 43.5 3.1 1.8 1 1 1 2 2 2 1 Poly(ADP-ribose) polymerase catalytic domain Aminotran_1_2 PF00155.21 OQR82041.1 - 1.2e-42 146.4 0.0 2.8e-42 145.2 0.0 1.6 2 0 0 2 2 2 1 Aminotransferase class I and II HAUS5 PF14817.6 OQR82041.1 - 7.2e-10 38.3 44.2 7.5e-06 25.0 11.3 3.4 1 1 1 2 2 2 2 HAUS augmin-like complex subunit 5 HTH_psq PF05225.16 OQR82041.1 - 2.6e-07 30.3 0.0 5.9e-07 29.1 0.0 1.6 1 0 0 1 1 1 1 helix-turn-helix, Psq domain Cep57_MT_bd PF06657.13 OQR82041.1 - 0.94 10.0 8.2 4.9 7.7 1.4 3.9 3 0 0 3 3 3 0 Centrosome microtubule-binding domain of Cep57 EF-hand_1 PF00036.32 OQR82042.1 - 8.1e-15 53.2 2.3 2.4e-06 26.7 0.2 2.5 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 OQR82042.1 - 6e-14 52.3 0.0 1.1e-13 51.4 0.0 1.5 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.6 OQR82042.1 - 6.5e-13 48.3 1.8 3.2e-07 30.1 0.1 2.9 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.6 OQR82042.1 - 8.7e-11 40.9 1.3 8.6e-06 25.3 0.2 2.6 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 OQR82042.1 - 6.1e-10 38.1 3.6 4.6e-06 25.9 0.6 2.5 2 0 0 2 2 2 2 EF hand SPARC_Ca_bdg PF10591.9 OQR82042.1 - 0.006 16.9 1.0 0.19 12.0 0.0 3.1 3 0 0 3 3 3 1 Secreted protein acidic and rich in cysteine Ca binding region Rap1a PF18602.1 OQR82042.1 - 0.06 13.7 0.1 0.23 11.8 0.1 2.0 1 0 0 1 1 1 0 Rap1a immunity proteins EF-hand_4 PF12763.7 OQR82042.1 - 0.12 12.4 1.1 6.6 6.7 0.0 2.5 1 1 1 2 2 2 0 Cytoskeletal-regulatory complex EF hand IQ PF00612.27 OQR82042.1 - 1.6 8.7 15.0 0.067 13.0 1.4 4.3 2 1 1 3 3 3 0 IQ calmodulin-binding motif Tubulin PF00091.25 OQR82043.1 - 4.7e-69 232.5 0.0 1e-68 231.5 0.0 1.6 2 0 0 2 2 2 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 OQR82043.1 - 4.8e-49 165.7 0.1 9.3e-49 164.8 0.1 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 OQR82043.1 - 1.1e-05 25.7 0.0 2.9e-05 24.4 0.0 1.7 1 1 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_2 PF13809.6 OQR82043.1 - 0.014 14.6 0.0 0.025 13.8 0.0 1.3 1 0 0 1 1 1 0 Tubulin like Hrs_helical PF12210.8 OQR82043.1 - 0.04 14.4 0.5 0.098 13.2 0.1 1.8 2 0 0 2 2 2 0 Hepatocyte growth factor-regulated tyrosine kinase substrate COX14 PF14880.6 OQR82044.1 - 0.1 12.4 0.3 0.28 11.1 0.0 1.8 2 0 0 2 2 2 0 Cytochrome oxidase c assembly Complex1_LYR_2 PF13233.6 OQR82045.1 - 3e-18 66.3 0.3 3.5e-18 66.1 0.3 1.1 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.15 OQR82045.1 - 2.3e-08 33.9 0.0 3.8e-08 33.2 0.0 1.4 1 0 0 1 1 1 1 Complex 1 protein (LYR family) CorA PF01544.18 OQR82045.1 - 0.057 12.7 0.2 0.062 12.6 0.2 1.2 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein DDE_1 PF03184.19 OQR82046.1 - 0.018 14.7 0.1 0.037 13.7 0.1 1.4 1 0 0 1 1 1 0 DDE superfamily endonuclease AAA_35 PF14516.6 OQR82046.1 - 0.16 10.8 0.3 2.3 7.0 0.1 2.1 2 0 0 2 2 2 0 AAA-like domain IBR PF01485.21 OQR82047.1 - 5e-18 65.1 23.9 1.5e-09 38.0 3.7 2.1 2 0 0 2 2 2 2 IBR domain, a half RING-finger domain zf-C2HC_2 PF13913.6 OQR82047.1 - 0.0046 16.8 14.2 0.038 13.9 5.6 3.1 2 0 0 2 2 2 2 zinc-finger of a C2HC-type zf-AN1 PF01428.16 OQR82047.1 - 0.053 13.7 4.4 0.053 13.7 4.4 3.2 2 2 1 3 3 3 0 AN1-like Zinc finger zf_UBZ PF18439.1 OQR82047.1 - 0.13 11.9 0.2 0.13 11.9 0.2 3.4 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger Pkinase PF00069.25 OQR82048.1 - 2.1e-72 243.7 0.0 2.7e-72 243.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQR82048.1 - 2.4e-34 118.8 0.0 3.1e-34 118.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase PX PF00787.24 OQR82048.1 - 4.5e-15 55.6 0.0 1.1e-14 54.4 0.0 1.6 1 0 0 1 1 1 1 PX domain Kinase-like PF14531.6 OQR82048.1 - 3.9e-08 33.0 0.0 6.3e-08 32.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_C PF00433.24 OQR82048.1 - 9.3e-06 26.3 4.8 2.4e-05 24.9 4.8 1.8 1 0 0 1 1 1 1 Protein kinase C terminal domain Pkinase_fungal PF17667.1 OQR82048.1 - 0.0018 17.1 0.0 0.0027 16.6 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase FTA2 PF13095.6 OQR82048.1 - 0.01 15.4 0.0 0.63 9.6 0.0 2.2 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 zf-CCCH PF00642.24 OQR82050.1 - 1.2e-19 69.7 16.4 2.3e-11 43.3 5.4 2.3 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 OQR82050.1 - 5.1e-13 48.6 16.8 2e-07 30.8 5.3 2.3 2 0 0 2 2 2 2 Zinc finger domain zf-CCCH_4 PF18044.1 OQR82050.1 - 7.3e-12 44.8 12.9 1.6e-06 27.8 2.5 2.4 2 0 0 2 2 2 2 CCCH-type zinc finger Torus PF16131.5 OQR82050.1 - 0.00036 21.2 10.4 0.023 15.4 0.7 2.4 1 1 1 2 2 2 2 Torus domain zf-CCCH_2 PF14608.6 OQR82050.1 - 0.00097 19.5 9.5 0.0087 16.5 1.5 2.5 2 0 0 2 2 2 2 RNA-binding, Nab2-type zinc finger PMR5N PF14416.6 OQR82050.1 - 1.3 9.4 3.5 8.4 6.8 0.4 2.4 1 1 1 2 2 2 0 PMR5 N terminal Domain FAM184 PF15665.5 OQR82051.1 - 0.0079 16.0 11.2 0.014 15.1 11.2 1.3 1 0 0 1 1 1 1 Family with sequence similarity 184, A and B DivIVA PF05103.13 OQR82051.1 - 0.037 14.1 13.0 0.081 13.0 13.0 1.5 1 0 0 1 1 1 0 DivIVA protein Muted PF14942.6 OQR82051.1 - 0.23 11.8 10.9 1 9.7 10.4 2.2 2 0 0 2 2 2 0 Organelle biogenesis, Muted-like protein JIP_LZII PF16471.5 OQR82051.1 - 2.5 8.3 6.8 3.9 7.7 0.8 2.5 2 0 0 2 2 2 0 JNK-interacting protein leucine zipper II DOPA_dioxygen PF08883.11 OQR82052.1 - 9e-27 93.4 0.4 1.5e-26 92.6 0.4 1.3 1 1 0 1 1 1 1 Dopa 4,5-dioxygenase family NfI_DNAbd_pre-N PF10524.9 OQR82052.1 - 0.092 12.6 0.7 0.93 9.4 0.1 2.3 2 0 0 2 2 2 0 Nuclear factor I protein pre-N-terminus PAZ PF02170.22 OQR82053.1 - 2e-22 79.5 0.2 3.7e-22 78.6 0.2 1.4 1 0 0 1 1 1 1 PAZ domain ArgoL1 PF08699.10 OQR82053.1 - 4.2e-20 71.1 0.1 1e-19 69.9 0.1 1.7 1 0 0 1 1 1 1 Argonaute linker 1 domain ArgoN PF16486.5 OQR82053.1 - 5.9e-18 65.8 0.4 1.1e-17 64.9 0.4 1.5 1 0 0 1 1 1 1 N-terminal domain of argonaute ArgoMid PF16487.5 OQR82053.1 - 2.6e-10 40.4 0.6 3.1e-09 37.0 0.0 2.7 3 0 0 3 3 3 1 Mid domain of argonaute ArgoL2 PF16488.5 OQR82053.1 - 5.8e-10 39.4 0.2 3.7e-09 36.8 0.0 2.5 4 0 0 4 4 4 1 Argonaute linker 2 domain MFS_1 PF07690.16 OQR82054.1 - 3e-33 115.2 39.2 5.9e-23 81.3 15.0 2.3 2 0 0 2 2 2 2 Major Facilitator Superfamily FYVE PF01363.21 OQR82054.1 - 1.8e-06 28.0 6.8 1.8e-06 28.0 6.8 2.5 3 0 0 3 3 3 1 FYVE zinc finger MFS_1_like PF12832.7 OQR82054.1 - 4.9e-06 25.7 13.3 0.0029 16.5 0.7 2.2 1 1 1 2 2 2 2 MFS_1 like family FYVE_2 PF02318.16 OQR82054.1 - 0.6 10.3 6.5 0.38 11.0 3.3 2.3 2 0 0 2 2 2 0 FYVE-type zinc finger Transp_Tc5_C PF04236.15 OQR82055.1 - 0.48 10.8 0.1 0.48 10.8 0.1 6.4 2 1 5 7 7 7 0 Tc5 transposase C-terminal domain SNARE PF05739.19 OQR82056.1 - 8.2e-13 48.1 0.2 8.2e-13 48.1 0.2 2.0 2 0 0 2 2 2 1 SNARE domain Syntaxin PF00804.25 OQR82056.1 - 8.7e-07 28.8 13.3 0.00098 18.8 0.7 2.6 3 0 0 3 3 3 2 Syntaxin GTA_holin_3TM PF11351.8 OQR82056.1 - 0.016 15.7 4.3 0.034 14.7 0.1 2.7 2 2 0 2 2 2 0 Holin of 3TMs, for gene-transfer release MCPsignal PF00015.21 OQR82056.1 - 0.037 13.8 0.3 0.037 13.8 0.3 2.2 2 0 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Syntaxin_2 PF14523.6 OQR82056.1 - 0.28 11.6 6.8 0.55 10.6 2.9 2.4 2 0 0 2 2 2 0 Syntaxin-like protein CC2-LZ PF16516.5 OQR82056.1 - 0.89 10.0 7.8 4.9 7.6 1.0 2.6 2 1 0 2 2 2 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator tRNA-synt_1 PF00133.22 OQR82057.1 - 2e-64 217.9 1.0 8.4e-43 146.5 6.2 6.0 2 1 1 3 3 3 3 tRNA synthetases class I (I, L, M and V) tRNA-synt_1_2 PF13603.6 OQR82057.1 - 2.7e-43 147.7 0.0 5.6e-43 146.6 0.0 1.5 1 0 0 1 1 1 1 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1g PF09334.11 OQR82057.1 - 1.5e-27 96.4 0.0 9.4e-20 70.7 0.0 4.6 4 1 1 5 5 5 3 tRNA synthetases class I (M) Anticodon_1 PF08264.13 OQR82057.1 - 2.3e-13 50.4 0.2 5.1e-13 49.2 0.2 1.6 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.19 OQR82057.1 - 0.00053 19.4 0.0 0.11 11.9 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain tRNA-synt_1f PF01921.18 OQR82057.1 - 0.1 11.5 0.0 1.4 7.7 0.0 2.2 2 0 0 2 2 2 0 tRNA synthetases class I (K) zf-ribbon_3 PF13248.6 OQR82057.1 - 1.2 8.7 4.9 0.89 9.1 0.6 2.3 2 0 0 2 2 2 0 zinc-ribbon domain DUF2935 PF11155.8 OQR82059.1 - 4.9 7.5 24.5 0.3 11.4 6.3 4.3 1 1 2 3 3 3 0 Domain of unknown function (DUF2935) FR47 PF08445.10 OQR82060.1 - 0.00019 21.3 0.0 0.0011 18.9 0.0 2.0 1 1 0 1 1 1 1 FR47-like protein Acetyltransf_3 PF13302.7 OQR82060.1 - 0.00052 20.7 0.0 0.0015 19.3 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain zf-RING_2 PF13639.6 OQR82061.1 - 9.1e-17 61.1 28.3 5.9e-09 36.1 6.3 3.5 3 0 0 3 3 3 2 Ring finger domain zf-RING_11 PF17123.5 OQR82061.1 - 5e-12 45.3 18.3 1e-06 28.4 4.2 3.0 2 0 0 2 2 2 2 RING-like zinc finger zf-RING_5 PF14634.6 OQR82061.1 - 1.1e-11 44.5 29.6 4.8e-07 29.6 5.2 3.8 3 0 0 3 3 3 2 zinc-RING finger domain zf-RING_UBOX PF13445.6 OQR82061.1 - 4.3e-10 39.5 27.4 2.5e-06 27.4 1.6 3.9 3 0 0 3 3 3 2 RING-type zinc-finger zf-C3HC4_2 PF13923.6 OQR82061.1 - 3.5e-08 33.2 21.8 0.00011 22.0 7.5 3.4 2 1 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 OQR82061.1 - 6.3e-08 32.6 19.7 0.00021 21.2 1.7 3.2 3 1 0 3 3 3 2 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 OQR82061.1 - 7.1e-08 32.6 26.9 5.8e-05 23.3 5.4 4.0 3 2 0 3 3 3 2 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 OQR82061.1 - 1.6e-06 27.9 17.6 0.00024 20.9 4.3 3.7 3 1 1 4 4 3 2 Zinc finger, C3HC4 type (RING finger) IQ PF00612.27 OQR82061.1 - 8.7e-06 25.1 0.1 2.4e-05 23.7 0.1 1.8 1 0 0 1 1 1 1 IQ calmodulin-binding motif zf-C3HC4_3 PF13920.6 OQR82061.1 - 0.00013 21.8 32.2 0.0035 17.2 5.3 3.7 3 1 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-RanBP PF00641.18 OQR82061.1 - 0.00018 20.7 1.4 0.00018 20.7 1.4 3.5 4 0 0 4 4 4 1 Zn-finger in Ran binding protein and others Zn_ribbon_17 PF17120.5 OQR82061.1 - 0.00048 19.7 24.1 0.00064 19.3 6.5 3.3 3 0 0 3 3 3 2 Zinc-ribbon, C4HC2 type zf-C3HC4_4 PF15227.6 OQR82061.1 - 0.0035 17.5 7.4 0.0035 17.5 7.4 3.3 3 1 0 3 3 2 2 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 OQR82061.1 - 0.0096 15.8 5.1 0.0096 15.8 5.1 4.5 3 1 1 4 4 4 2 Prokaryotic RING finger family 4 zf-RING_4 PF14570.6 OQR82061.1 - 0.87 9.4 28.2 0.3 10.9 3.6 4.1 3 1 1 4 4 4 0 RING/Ubox like zinc-binding domain zf-C3H2C3 PF17122.5 OQR82061.1 - 1.9 8.6 25.7 1 9.5 5.8 4.6 2 2 1 3 3 3 0 Zinc-finger EF-hand_1 PF00036.32 OQR82062.1 - 0.02 14.4 0.0 0.17 11.5 0.0 2.4 2 0 0 2 2 2 0 EF hand EF-hand_8 PF13833.6 OQR82062.1 - 0.024 14.5 0.1 7.6 6.5 0.0 3.7 3 1 0 3 3 3 0 EF-hand domain pair DUF5580 PF17743.1 OQR82062.1 - 0.036 12.6 0.0 0.061 11.9 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5580) EF-hand_6 PF13405.6 OQR82062.1 - 0.038 13.9 0.0 0.19 11.7 0.0 2.2 2 0 0 2 2 2 0 EF-hand domain TGT PF01702.18 OQR82063.1 - 8.1e-79 265.3 0.0 9.6e-79 265.1 0.0 1.0 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase Arm-DNA-bind_2 PF12167.8 OQR82063.1 - 0.13 12.2 0.3 0.32 11.0 0.3 1.6 1 0 0 1 1 1 0 Arm DNA-binding domain FYVE PF01363.21 OQR82064.1 - 0.00057 20.0 12.7 0.0014 18.7 12.8 1.6 1 1 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.16 OQR82064.1 - 0.49 10.6 6.6 0.96 9.7 6.6 1.5 1 0 0 1 1 1 0 FYVE-type zinc finger TauD PF02668.16 OQR82065.1 - 5.4e-41 141.2 0.1 9.9e-41 140.3 0.1 1.4 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF971 PF06155.12 OQR82065.1 - 6.1e-16 58.8 0.5 1.6e-14 54.3 0.1 2.5 1 1 1 2 2 2 2 Protein of unknown function (DUF971) HD PF01966.22 OQR82065.1 - 2e-06 28.0 0.3 4.3e-06 27.0 0.3 1.5 1 0 0 1 1 1 1 HD domain CsiD PF08943.10 OQR82065.1 - 0.0046 16.1 0.0 0.0094 15.1 0.0 1.4 1 0 0 1 1 1 1 CsiD HD_4 PF13328.6 OQR82065.1 - 0.054 13.2 0.0 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 HD domain HDOD PF08668.12 OQR82065.1 - 0.071 12.6 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 HDOD domain Big_4 PF07532.11 OQR82065.1 - 0.31 10.8 1.2 0.65 9.8 0.6 1.9 2 0 0 2 2 2 0 Bacterial Ig-like domain (group 4) AAA_16 PF13191.6 OQR82066.1 - 3e-05 24.5 0.0 0.00044 20.7 0.0 3.0 2 0 0 2 2 2 1 AAA ATPase domain AAA_23 PF13476.6 OQR82066.1 - 7.5 7.0 0.0 7.5 7.0 0.0 4.4 4 1 0 4 4 4 0 AAA domain CN_hydrolase PF00795.22 OQR82068.1 - 3.1e-25 89.0 0.0 3.7e-25 88.8 0.0 1.0 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Kelch_1 PF01344.25 OQR82068.1 - 0.0054 16.3 0.1 0.31 10.6 0.0 2.6 3 0 0 3 3 3 1 Kelch motif Kelch_5 PF13854.6 OQR82068.1 - 0.016 15.2 0.0 0.039 14.0 0.0 1.6 2 0 0 2 2 2 0 Kelch motif YjbT PF17089.5 OQR82068.1 - 0.13 12.3 0.0 0.25 11.4 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family Herpes_UL49_5 PF05702.11 OQR82070.1 - 0.55 10.3 4.1 1.9 8.7 4.1 1.8 1 0 0 1 1 1 0 Herpesvirus UL49.5 envelope/tegument protein BING4CT PF08149.11 OQR82071.1 - 9.1e-40 134.3 0.0 1.6e-37 127.2 0.0 3.3 3 0 0 3 3 3 1 BING4CT (NUC141) domain WD40_like PF17005.5 OQR82071.1 - 3.9e-08 33.0 0.0 0.0014 18.0 0.0 2.1 2 0 0 2 2 2 2 WD40-like domain ANAPC4_WD40 PF12894.7 OQR82071.1 - 6.1e-05 23.2 0.0 1 9.7 0.0 4.3 1 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 OQR82071.1 - 0.0002 22.1 0.0 0.033 15.1 0.0 3.7 4 0 0 4 4 4 1 WD domain, G-beta repeat Lipase_3 PF01764.25 OQR82073.1 - 2.4e-28 98.8 0.0 6e-28 97.5 0.0 1.7 1 0 0 1 1 1 1 Lipase (class 3) DUF2974 PF11187.8 OQR82073.1 - 0.00023 20.8 0.1 0.015 14.9 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF2974) Abhydrolase_5 PF12695.7 OQR82073.1 - 0.017 14.9 0.0 0.039 13.7 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_6 PF12697.7 OQR82073.1 - 0.063 13.9 1.5 0.11 13.1 0.0 2.1 2 1 0 2 2 2 0 Alpha/beta hydrolase family CCT PF06203.14 OQR82074.1 - 5.1e-17 61.6 9.1 8.2e-17 61.0 9.1 1.3 1 0 0 1 1 1 1 CCT motif CCT_2 PF09425.10 OQR82074.1 - 0.62 10.0 3.1 1.2 9.0 3.1 1.5 1 0 0 1 1 1 0 Divergent CCT motif 3Beta_HSD PF01073.19 OQR82076.1 - 1.2e-57 195.1 0.0 1.6e-57 194.7 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 OQR82076.1 - 7.9e-34 117.2 0.0 2.1e-33 115.8 0.0 1.6 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 OQR82076.1 - 6.8e-20 71.7 0.0 7.5e-19 68.3 0.1 2.3 2 1 0 2 2 2 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 OQR82076.1 - 4.6e-19 69.0 0.0 8.7e-19 68.1 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.12 OQR82076.1 - 2e-18 66.5 0.6 1.2e-14 54.1 0.0 2.2 2 0 0 2 2 2 2 Male sterility protein Cyt-b5 PF00173.28 OQR82076.1 - 6.9e-18 64.6 0.0 1.3e-17 63.7 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain NmrA PF05368.13 OQR82076.1 - 7.5e-09 35.5 0.0 1.2e-08 34.9 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family Polysacc_synt_2 PF02719.15 OQR82076.1 - 7.9e-09 35.1 1.7 1.7e-07 30.6 1.7 2.2 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 OQR82076.1 - 1.4e-08 34.2 0.0 2.1e-08 33.6 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain KR PF08659.10 OQR82076.1 - 2.2e-06 27.7 3.1 0.00018 21.5 3.1 3.2 1 1 0 1 1 1 1 KR domain adh_short PF00106.25 OQR82076.1 - 0.00088 18.8 0.0 0.0021 17.5 0.0 1.7 1 0 0 1 1 1 1 short chain dehydrogenase RNase_T PF00929.24 OQR82077.1 - 1.2e-13 51.9 0.1 1.9e-13 51.3 0.1 1.3 1 0 0 1 1 1 1 Exonuclease zf_CCCH_4 PF18345.1 OQR82077.1 - 2.7e-10 39.9 18.5 2.8e-05 24.0 3.5 2.4 2 0 0 2 2 2 2 Zinc finger domain zf-CCCH_4 PF18044.1 OQR82077.1 - 5.2e-08 32.5 16.7 0.00023 20.9 3.3 2.7 3 0 0 3 3 3 2 CCCH-type zinc finger zf-CCCH PF00642.24 OQR82077.1 - 5e-07 29.5 13.6 1.9e-05 24.4 4.7 2.3 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_3 PF15663.5 OQR82077.1 - 9.4e-06 25.8 2.2 0.061 13.5 0.1 2.4 2 0 0 2 2 2 2 Zinc-finger containing family zf-CCCH_2 PF14608.6 OQR82077.1 - 0.0012 19.2 13.6 0.0018 18.7 2.6 2.6 2 0 0 2 2 2 1 RNA-binding, Nab2-type zinc finger Torus PF16131.5 OQR82077.1 - 0.0023 18.6 8.9 0.032 14.9 1.6 2.4 1 1 1 2 2 2 2 Torus domain DNA_pol_A_exo1 PF01612.20 OQR82077.1 - 0.047 13.4 0.1 0.21 11.3 0.1 2.0 1 1 0 1 1 1 0 3'-5' exonuclease Gemini_AL1_M PF08283.11 OQR82077.1 - 0.16 12.1 0.0 0.31 11.1 0.0 1.4 1 0 0 1 1 1 0 Geminivirus rep protein central domain MFS_1 PF07690.16 OQR82078.1 - 3.5e-11 42.6 10.8 4.3e-11 42.3 10.8 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF4483 PF14825.6 OQR82079.1 - 1.7e-27 96.1 0.0 2.4e-27 95.7 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4483) Abhydrolase_3 PF07859.13 OQR82080.1 - 5.6e-41 140.7 0.0 8.4e-41 140.1 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 OQR82080.1 - 4.9e-13 48.7 0.0 7.5e-13 48.1 0.0 1.2 1 0 0 1 1 1 1 Steryl acetyl hydrolase Hydrolase_4 PF12146.8 OQR82080.1 - 0.011 15.0 0.1 0.088 12.1 0.0 2.4 2 1 0 2 2 2 0 Serine aminopeptidase, S33 COesterase PF00135.28 OQR82080.1 - 0.047 12.6 0.1 1.4 7.7 0.0 2.1 2 0 0 2 2 2 0 Carboxylesterase family TMEM173 PF15009.6 OQR82080.1 - 0.19 10.8 0.5 3.8 6.6 0.1 2.2 1 1 1 2 2 2 0 Transmembrane protein 173 RRM_1 PF00076.22 OQR82081.1 - 3.5e-14 52.4 0.0 8.6e-14 51.1 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PPTA PF01239.22 OQR82081.1 - 2.7e-07 30.1 22.8 2.8e-05 23.7 1.2 5.6 5 0 0 5 5 5 3 Protein prenyltransferase alpha subunit repeat SLC35F PF06027.12 OQR82081.1 - 5e-07 29.5 4.0 1.3e-06 28.2 4.0 1.6 1 0 0 1 1 1 1 Solute carrier family 35 EamA PF00892.20 OQR82081.1 - 1.6e-05 25.0 8.2 1.6e-05 25.0 8.2 3.2 2 1 0 2 2 2 1 EamA-like transporter family PUNUT PF16913.5 OQR82081.1 - 1.9e-05 24.1 3.8 3.3e-05 23.3 3.8 1.3 1 0 0 1 1 1 1 Purine nucleobase transmembrane transport Nuc_sug_transp PF04142.15 OQR82081.1 - 0.00082 18.6 2.3 0.0017 17.6 2.3 1.4 1 0 0 1 1 1 1 Nucleotide-sugar transporter Spo7_2_N PF15407.6 OQR82081.1 - 0.0047 16.5 0.1 0.012 15.3 0.1 1.7 1 0 0 1 1 1 1 Sporulation protein family 7 WD40_alt PF14077.6 OQR82081.1 - 0.015 15.2 0.2 0.039 13.8 0.2 1.6 1 0 0 1 1 1 0 Alternative WD40 repeat motif Tup_N PF08581.10 OQR82081.1 - 1.5 9.1 13.5 0.15 12.4 1.6 3.8 4 0 0 4 4 4 0 Tup N-terminal DUF2730 PF10805.8 OQR82081.1 - 4.2 7.5 5.9 3 8.0 1.1 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2730) PseudoU_synth_2 PF00849.22 OQR82083.1 - 6.9e-32 110.7 0.1 9.1e-32 110.3 0.1 1.2 1 0 0 1 1 1 1 RNA pseudouridylate synthase Sulfate_transp PF00916.20 OQR82084.1 - 4.2e-41 141.0 24.3 6e-41 140.5 24.3 1.3 1 0 0 1 1 1 1 Sulfate permease family STAS_2 PF13466.6 OQR82084.1 - 0.0003 21.1 0.0 0.00072 19.8 0.0 1.6 1 0 0 1 1 1 1 STAS domain MFS_MOT1 PF16983.5 OQR82084.1 - 0.0048 17.3 34.2 0.027 14.9 7.5 4.4 4 1 0 4 4 4 2 Molybdate transporter of MFS superfamily STAS PF01740.21 OQR82084.1 - 0.028 14.1 0.0 0.068 12.8 0.0 1.6 1 0 0 1 1 1 0 STAS domain DUF2975 PF11188.8 OQR82084.1 - 0.028 14.3 0.4 0.028 14.3 0.4 3.5 2 2 1 3 3 3 0 Protein of unknown function (DUF2975) Na_Ca_ex PF01699.24 OQR82085.1 - 3.2e-39 134.3 40.6 2.9e-22 79.2 18.2 2.3 2 0 0 2 2 2 2 Sodium/calcium exchanger protein Cyt_c_ox_IV PF12270.8 OQR82085.1 - 0.044 13.9 0.2 0.044 13.9 0.2 2.9 3 1 1 4 4 4 0 Cytochrome c oxidase subunit IV DUF4293 PF14126.6 OQR82085.1 - 0.36 11.1 0.1 0.36 11.1 0.1 3.3 3 2 1 4 4 4 0 Domain of unknown function (DUF4293) 7TM_GPCR_Srab PF10292.9 OQR82085.1 - 0.38 9.6 4.5 0.15 10.9 0.2 2.1 2 0 0 2 2 2 0 Serpentine type 7TM GPCR receptor class ab chemoreceptor DEAD_2 PF06733.15 OQR82086.1 - 2.2e-51 174.0 1.0 4.6e-51 172.9 1.0 1.6 1 0 0 1 1 1 1 DEAD_2 ResIII PF04851.15 OQR82086.1 - 2.8e-06 27.5 0.3 0.067 13.2 0.1 3.0 2 1 0 2 2 2 2 Type III restriction enzyme, res subunit PhoH PF02562.16 OQR82086.1 - 0.0011 18.4 0.0 0.67 9.4 0.0 2.3 2 0 0 2 2 2 2 PhoH-like protein FKBP_C PF00254.28 OQR82087.1 - 4e-28 97.6 0.0 7.6e-28 96.7 0.0 1.5 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase EF-hand_7 PF13499.6 OQR82087.1 - 4.8e-28 97.4 1.2 3.5e-13 49.8 0.2 2.5 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 OQR82087.1 - 6.1e-28 94.3 9.4 8.2e-07 28.1 0.2 4.5 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.6 OQR82087.1 - 1.4e-21 74.5 5.0 1.2e-05 24.8 0.1 4.5 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 OQR82087.1 - 2e-20 71.3 5.8 2.5e-06 26.7 0.1 4.5 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.6 OQR82087.1 - 2.9e-18 65.5 6.8 3e-07 30.2 0.3 4.3 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_9 PF14658.6 OQR82087.1 - 1.5e-11 44.5 0.1 9.3e-05 22.7 0.0 2.5 2 0 0 2 2 2 2 EF-hand domain WW PF00397.26 OQR82087.1 - 3.8e-08 33.3 4.4 7e-08 32.4 4.4 1.5 1 0 0 1 1 1 1 WW domain SPARC_Ca_bdg PF10591.9 OQR82087.1 - 1.9e-07 31.4 0.6 0.015 15.7 0.0 2.8 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region IQ PF00612.27 OQR82087.1 - 2.7e-05 23.6 0.7 6.9e-05 22.3 0.7 1.7 1 0 0 1 1 1 1 IQ calmodulin-binding motif EF-hand_11 PF08976.11 OQR82087.1 - 0.023 15.6 0.2 0.071 14.0 0.0 1.9 2 0 0 2 2 2 0 EF-hand domain Queuosine_synth PF02547.15 OQR82088.1 - 9.7e-94 314.1 0.0 1.1e-93 313.9 0.0 1.0 1 0 0 1 1 1 1 Queuosine biosynthesis protein GlcNAc PF11397.8 OQR82091.1 - 1.4e-92 310.9 0.0 4.9e-41 141.3 0.0 4.3 2 2 1 3 3 3 3 Glycosyltransferase (GlcNAc) FYVE PF01363.21 OQR82091.1 - 2e-18 66.3 37.2 5.2e-10 39.3 11.0 2.8 2 0 0 2 2 2 2 FYVE zinc finger FYVE_2 PF02318.16 OQR82091.1 - 1.1e-05 25.7 21.7 0.0066 16.7 8.2 2.7 2 0 0 2 2 2 2 FYVE-type zinc finger START PF01852.19 OQR82091.1 - 0.0072 15.8 0.7 0.077 12.4 0.1 2.4 2 0 0 2 2 2 1 START domain GST_N_3 PF13417.6 OQR82093.1 - 2.4e-11 43.9 0.1 5e-11 42.8 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 OQR82093.1 - 3e-08 33.8 0.9 5.4e-08 33.0 0.1 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 OQR82093.1 - 2.2e-07 31.1 0.2 6.4e-07 29.6 0.1 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 OQR82093.1 - 0.00081 19.4 0.1 0.002 18.1 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 OQR82093.1 - 0.027 14.7 0.0 0.041 14.1 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Skp1_POZ PF03931.15 OQR82100.1 - 8.8e-50 166.7 5.0 9.8e-15 54.5 0.0 4.5 4 0 0 4 4 4 4 Skp1 family, tetramerisation domain Skp1 PF01466.19 OQR82100.1 - 2.9e-32 110.5 1.4 1.9e-10 40.7 0.4 3.7 3 0 0 3 3 3 3 Skp1 family, dimerisation domain BTB PF00651.31 OQR82100.1 - 0.00083 19.6 3.3 11 6.2 0.1 4.3 3 2 0 3 3 3 3 BTB/POZ domain DUF1450 PF07293.11 OQR82100.1 - 0.0017 18.1 0.2 1.9 8.4 0.0 3.4 3 0 0 3 3 3 2 Protein of unknown function (DUF1450) THOC7 PF05615.13 OQR82102.1 - 1.3e-14 54.6 1.5 1.3e-14 54.6 1.5 2.2 1 1 1 2 2 2 1 Tho complex subunit 7 Gag_p17 PF00540.18 OQR82102.1 - 0.0097 15.9 1.3 0.041 13.9 0.3 2.3 1 1 2 3 3 3 1 gag gene protein p17 (matrix protein) DUF848 PF05852.11 OQR82102.1 - 0.024 14.7 4.6 0.024 14.7 4.6 2.3 1 1 1 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) DUF4407 PF14362.6 OQR82102.1 - 0.91 8.8 10.0 1.3 8.3 10.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) zf-C4H2 PF10146.9 OQR82102.1 - 6.4 7.0 12.8 2.1 8.6 4.4 2.1 1 1 1 2 2 2 0 Zinc finger-containing protein Reg_prop PF07494.11 OQR82103.1 - 0.067 13.4 0.0 0.37 11.2 0.0 2.4 1 0 0 1 1 1 0 Two component regulator propeller zf-CCCH_4 PF18044.1 OQR82104.1 - 5.3e-06 26.1 4.2 5.3e-06 26.1 4.2 1.8 2 0 0 2 2 2 1 CCCH-type zinc finger zf-CCCH PF00642.24 OQR82104.1 - 7.4e-06 25.8 2.9 1.5e-05 24.8 2.9 1.5 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 OQR82104.1 - 1e-05 25.4 6.2 2.3e-05 24.3 6.2 1.6 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH_2 PF14608.6 OQR82104.1 - 0.08 13.4 4.9 0.16 12.5 4.9 1.5 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger Torus PF16131.5 OQR82104.1 - 0.099 13.4 1.4 0.22 12.3 0.1 2.3 2 0 0 2 2 2 0 Torus domain RAG1_imp_bd PF12560.8 OQR82104.1 - 0.12 11.8 0.1 0.22 11.0 0.1 1.3 1 0 0 1 1 1 0 RAG1 importin binding WD40 PF00400.32 OQR82105.1 - 3e-32 110.1 15.5 3.2e-06 27.8 1.3 10.3 10 0 0 10 10 10 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OQR82105.1 - 5.5e-11 42.6 3.6 1.1 9.6 0.1 7.1 4 4 4 8 8 8 5 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 OQR82105.1 - 4.5e-06 26.7 0.3 1.7 8.5 0.0 3.5 3 0 0 3 3 3 3 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 OQR82105.1 - 0.00014 20.6 2.0 0.25 9.9 0.1 3.7 3 1 0 3 3 3 3 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 OQR82105.1 - 0.031 13.3 4.3 0.68 8.8 0.5 4.3 2 2 2 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Kin17_mid PF10357.9 OQR82107.1 - 2.2e-48 163.3 1.5 2.2e-48 163.3 1.5 2.2 2 0 0 2 2 2 1 Domain of Kin17 curved DNA-binding protein A_deaminase PF00962.22 OQR82107.1 - 6.2e-43 147.4 0.3 2.4e-31 109.3 0.2 2.4 1 1 1 2 2 2 2 Adenosine/AMP deaminase KN17_SH3 PF18131.1 OQR82107.1 - 5.1e-22 77.7 7.5 5.1e-22 77.7 7.5 2.8 4 0 0 4 4 4 1 KN17 SH3-like C-terminal domain zf-B_box PF00643.24 OQR82107.1 - 6.8e-10 38.9 33.2 2.4e-07 30.8 3.3 4.1 4 0 0 4 4 4 2 B-box zinc finger zf-C2H2_jaz PF12171.8 OQR82107.1 - 0.0037 17.5 4.3 0.0037 17.5 4.3 3.4 4 0 0 4 4 4 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 OQR82107.1 - 0.0058 17.0 5.0 0.0058 17.0 5.0 3.0 3 0 0 3 3 3 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 OQR82107.1 - 0.035 14.4 0.4 0.035 14.4 0.4 4.1 3 1 1 4 4 4 0 C2H2 type zinc-finger (2 copies) PARP PF00644.20 OQR82107.1 - 0.061 12.9 0.3 0.24 10.9 0.3 2.1 1 1 0 1 1 1 0 Poly(ADP-ribose) polymerase catalytic domain PTAC PF06130.12 OQR82107.1 - 0.08 13.1 0.8 3.5 7.8 0.2 2.9 2 0 0 2 2 2 0 Phosphate propanoyltransferase PhzC-PhzF PF02567.16 OQR82109.1 - 4.1e-66 223.3 0.0 5.3e-66 223.0 0.0 1.1 1 0 0 1 1 1 1 Phenazine biosynthesis-like protein Acetyltransf_1 PF00583.25 OQR82109.1 - 5.4e-13 49.2 0.0 1.1e-12 48.2 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 OQR82109.1 - 4.4e-12 46.0 0.0 1.1e-11 44.8 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 OQR82109.1 - 1e-08 35.5 0.0 2.4e-08 34.3 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 OQR82109.1 - 2.5e-06 27.6 0.0 5.3e-06 26.5 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 OQR82109.1 - 3.4e-05 23.9 0.0 0.0028 17.7 0.0 2.8 2 0 0 2 2 2 1 GCN5-related N-acetyl-transferase Acetyltransf_15 PF17013.5 OQR82109.1 - 0.0013 18.3 0.0 0.0019 17.7 0.0 1.2 1 0 0 1 1 1 1 Putative acetyl-transferase Acetyltransf_13 PF13880.6 OQR82109.1 - 0.0024 17.8 0.1 0.0052 16.7 0.1 1.5 1 0 0 1 1 1 1 ESCO1/2 acetyl-transferase DUF547 PF04784.14 OQR82111.1 - 5.8e-18 65.1 0.1 9.1e-18 64.5 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF547 EF-hand_1 PF00036.32 OQR82112.1 - 5.6e-26 88.1 13.5 5.7e-08 31.8 0.0 4.4 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 OQR82112.1 - 1.9e-24 85.9 6.9 1.2e-13 51.3 0.3 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 OQR82112.1 - 2.4e-19 67.5 4.8 3.1e-08 32.9 0.0 4.6 4 0 0 4 4 4 3 EF-hand domain EF-hand_8 PF13833.6 OQR82112.1 - 2.4e-17 62.5 13.8 5.6e-08 32.5 0.5 4.3 2 2 2 4 4 4 4 EF-hand domain pair zf-RING_2 PF13639.6 OQR82112.1 - 1.7e-12 47.5 5.5 1.7e-12 47.5 5.5 1.8 2 0 0 2 2 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 OQR82112.1 - 9.6e-12 44.6 5.5 1.9e-11 43.6 5.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) PA PF02225.22 OQR82112.1 - 5.9e-11 42.2 0.0 1.3e-10 41.2 0.0 1.6 1 0 0 1 1 1 1 PA domain zf-C3HC4 PF00097.25 OQR82112.1 - 4e-10 39.4 4.8 7.7e-10 38.5 4.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 OQR82112.1 - 6.1e-09 36.0 5.0 1.2e-08 35.1 3.7 2.2 2 0 0 2 2 1 1 RING-H2 zinc finger domain zf-RING_11 PF17123.5 OQR82112.1 - 9.2e-09 34.9 4.0 2.7e-08 33.4 4.0 1.8 1 0 0 1 1 1 1 RING-like zinc finger EF-hand_9 PF14658.6 OQR82112.1 - 4.6e-08 33.3 0.3 0.011 16.1 0.0 2.4 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 OQR82112.1 - 4.8e-08 32.1 9.6 4.6e-05 22.7 0.1 4.3 4 0 0 4 4 4 2 EF hand zf-RING_UBOX PF13445.6 OQR82112.1 - 8e-08 32.2 2.4 2.3e-07 30.7 2.5 1.8 1 1 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 OQR82112.1 - 3.4e-06 26.9 3.7 6.1e-06 26.1 3.7 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 OQR82112.1 - 4.4e-06 26.5 2.4 7.9e-06 25.6 2.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 OQR82112.1 - 7e-05 22.6 2.6 0.00013 21.7 2.6 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 Zf_RING PF16744.5 OQR82112.1 - 0.00062 19.8 2.6 0.0018 18.4 1.0 2.3 2 0 0 2 2 2 1 KIAA1045 RING finger zf-ANAPC11 PF12861.7 OQR82112.1 - 0.00066 19.7 4.2 0.0022 18.0 3.1 2.4 2 1 0 2 2 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_ribbon_17 PF17120.5 OQR82112.1 - 0.0013 18.3 2.9 0.0026 17.3 2.9 1.5 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type FHIPEP PF00771.20 OQR82112.1 - 0.0017 16.9 0.6 1.1 7.7 0.0 2.8 2 1 1 3 3 3 1 FHIPEP family SurA_N_3 PF13624.6 OQR82112.1 - 0.004 17.0 1.6 0.007 16.2 0.6 2.0 2 0 0 2 2 2 1 SurA N-terminal domain PepSY_2 PF13670.6 OQR82112.1 - 0.0048 16.9 7.8 0.59 10.2 0.5 3.9 3 1 1 4 4 4 1 Peptidase propeptide and YPEB domain zf-RING_4 PF14570.6 OQR82112.1 - 0.011 15.5 4.9 0.029 14.2 4.9 1.7 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain PHD PF00628.29 OQR82112.1 - 0.012 15.5 4.4 0.025 14.5 4.4 1.6 1 0 0 1 1 1 0 PHD-finger zf-C3HC4_4 PF15227.6 OQR82112.1 - 0.021 15.0 6.0 0.021 15.0 6.0 1.8 2 0 0 2 2 1 0 zinc finger of C3HC4-type, RING DUF3911 PF13050.6 OQR82112.1 - 0.027 14.6 5.3 0.18 11.9 0.4 2.8 2 1 1 3 3 2 0 Protein of unknown function (DUF3911) TerB PF05099.13 OQR82112.1 - 0.028 14.4 1.0 0.064 13.2 1.0 1.6 1 0 0 1 1 1 0 Tellurite resistance protein TerB U-box PF04564.15 OQR82112.1 - 0.037 14.2 0.0 0.097 12.9 0.0 1.7 1 0 0 1 1 1 0 U-box domain zf-RING-like PF08746.11 OQR82112.1 - 0.038 14.3 2.8 0.083 13.2 2.8 1.6 1 0 0 1 1 1 0 RING-like domain SUB1_ProdP9 PF18213.1 OQR82112.1 - 0.042 13.7 0.2 0.14 12.1 0.2 1.9 1 0 0 1 1 1 0 SUB1 protease Prodomain ProdP9 LETM1 PF07766.13 OQR82112.1 - 0.045 13.1 1.1 0.15 11.4 0.9 1.8 1 1 1 2 2 2 0 LETM1-like protein ERAP1_C PF11838.8 OQR82112.1 - 0.048 13.2 0.1 0.072 12.6 0.1 1.2 1 0 0 1 1 1 0 ERAP1-like C-terminal domain LapA_dom PF06305.11 OQR82112.1 - 0.05 13.4 1.7 0.23 11.3 0.2 2.4 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain SurA_N_2 PF13623.6 OQR82112.1 - 0.094 12.6 2.2 3.2 7.6 0.2 2.7 1 1 1 2 2 2 0 SurA N-terminal domain EF-hand_14 PF17959.1 OQR82112.1 - 0.098 13.0 0.8 6.7 7.1 0.1 2.4 2 0 0 2 2 2 0 EF-hand domain RINGv PF12906.7 OQR82112.1 - 0.11 12.6 4.9 0.34 11.1 4.9 1.9 1 0 0 1 1 1 0 RING-variant domain zf-C3H2C3 PF17122.5 OQR82112.1 - 0.13 12.4 1.4 0.38 10.8 1.4 1.8 1 0 0 1 1 1 0 Zinc-finger EF-hand_4 PF12763.7 OQR82112.1 - 0.14 12.1 5.3 19 5.3 0.3 3.6 1 1 2 3 3 3 0 Cytoskeletal-regulatory complex EF hand Prok-RING_1 PF14446.6 OQR82112.1 - 0.17 11.8 5.5 1.5 8.8 5.6 2.2 1 1 1 2 2 2 0 Prokaryotic RING finger family 1 DUF1418 PF07214.12 OQR82112.1 - 0.2 11.6 1.1 0.61 10.0 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1418) DUF3899 PF13038.6 OQR82112.1 - 0.33 11.5 1.5 1 9.9 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3899) HemY_N PF07219.13 OQR82112.1 - 0.45 10.7 2.3 11 6.3 0.5 2.5 2 0 0 2 2 2 0 HemY protein N-terminus FANCL_C PF11793.8 OQR82112.1 - 0.7 10.1 6.2 6.8 7.0 6.2 2.4 1 1 0 1 1 1 0 FANCL C-terminal domain Longin PF13774.6 OQR82114.1 - 1.1e-22 79.8 0.0 1.8e-22 79.2 0.0 1.3 1 0 0 1 1 1 1 Regulated-SNARE-like domain Synaptobrevin PF00957.21 OQR82114.1 - 5.3e-15 55.0 0.6 7.8e-15 54.5 0.1 1.5 2 0 0 2 2 2 1 Synaptobrevin COQ9 PF08511.11 OQR82114.1 - 0.0043 16.8 0.1 0.013 15.2 0.1 1.9 1 1 0 1 1 1 1 COQ9 Sec20 PF03908.13 OQR82114.1 - 1.9 8.4 4.5 27 4.8 2.3 3.0 2 1 0 2 2 2 0 Sec20 Nfu_N PF08712.11 OQR82115.1 - 5.8e-29 100.0 0.0 1.6e-28 98.6 0.0 1.8 1 0 0 1 1 1 1 Scaffold protein Nfu/NifU N terminal NifU PF01106.17 OQR82115.1 - 1.5e-26 92.3 0.1 2.6e-26 91.6 0.1 1.4 1 0 0 1 1 1 1 NifU-like domain PGI PF00342.19 OQR82115.1 - 0.06 11.9 0.1 0.083 11.5 0.1 1.1 1 0 0 1 1 1 0 Phosphoglucose isomerase CBM_1 PF00734.18 OQR82116.1 - 1.2e-05 25.2 11.2 1.2e-05 25.2 11.2 3.0 3 0 0 3 3 3 1 Fungal cellulose binding domain AgrB PF04647.15 OQR82118.1 - 0.0064 15.8 0.0 0.012 15.0 0.0 1.4 1 0 0 1 1 1 1 Accessory gene regulator B DUF4194 PF13835.6 OQR82118.1 - 0.03 14.1 0.3 0.052 13.3 0.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4194) YlqD PF11068.8 OQR82118.1 - 0.032 14.6 0.7 0.044 14.2 0.7 1.2 1 0 0 1 1 1 0 YlqD protein Type_III_YscG PF09477.10 OQR82118.1 - 0.11 12.6 0.6 4.2 7.5 0.1 2.4 2 1 0 2 2 2 0 Bacterial type II secretion system chaperone protein (type_III_yscG) Uteroglobin PF01099.17 OQR82118.1 - 0.19 12.1 1.5 1.5 9.2 0.2 2.7 3 0 0 3 3 3 0 Uteroglobin family B9-C2 PF07162.11 OQR82119.1 - 2.2e-19 70.3 0.1 3.6e-19 69.6 0.1 1.3 1 0 0 1 1 1 1 Ciliary basal body-associated, B9 protein YHYH PF14240.6 OQR82123.1 - 1.2e-20 74.4 9.6 1.7e-12 47.7 0.0 4.6 2 2 2 4 4 4 3 YHYH protein F5_F8_type_C PF00754.25 OQR82123.1 - 0.0046 17.1 0.3 0.05 13.7 0.0 2.7 3 0 0 3 3 3 1 F5/8 type C domain Pkinase PF00069.25 OQR82129.1 - 9.9e-48 162.8 0.0 1.2e-47 162.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQR82129.1 - 1.8e-47 161.8 0.0 2.3e-47 161.5 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OQR82129.1 - 3.2e-05 22.9 0.0 4e-05 22.6 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 OQR82129.1 - 0.00047 20.1 0.0 0.00071 19.6 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 OQR82129.1 - 0.12 11.3 0.0 0.33 9.8 0.0 1.6 2 0 0 2 2 2 0 Haspin like kinase domain Kinase-like PF14531.6 OQR82129.1 - 0.15 11.3 0.0 0.23 10.7 0.0 1.3 1 0 0 1 1 1 0 Kinase-like EBP PF05241.12 OQR82131.1 - 2.4e-32 111.8 9.9 2.9e-32 111.5 9.9 1.1 1 0 0 1 1 1 1 Emopamil binding protein PHB_acc PF05233.13 OQR82131.1 - 0.0024 17.9 0.3 0.0049 16.9 0.3 1.5 1 0 0 1 1 1 1 PHB accumulation regulatory domain DUF2781 PF10914.8 OQR82131.1 - 0.0036 17.7 5.9 0.0036 17.7 5.9 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF2781) DUF3377 PF11857.8 OQR82131.1 - 0.85 9.6 3.1 1.6 8.7 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3377) MatE PF01554.18 OQR82132.1 - 3.5e-34 117.8 37.5 1.9e-17 63.4 18.3 2.3 2 0 0 2 2 2 2 MatE Thioredoxin PF00085.20 OQR82133.1 - 1.8e-15 56.7 0.0 3.7e-15 55.8 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin Evr1_Alr PF04777.13 OQR82133.1 - 2.2e-14 53.7 0.8 5.3e-14 52.5 0.8 1.7 1 0 0 1 1 1 1 Erv1 / Alr family Thioredoxin_2 PF13098.6 OQR82133.1 - 0.00038 20.9 0.0 0.01 16.3 0.0 2.5 2 0 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_9 PF14595.6 OQR82133.1 - 0.05 13.4 0.0 0.095 12.5 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin Thioredoxin_8 PF13905.6 OQR82133.1 - 0.068 13.5 0.0 0.38 11.1 0.0 2.1 1 1 1 2 2 2 0 Thioredoxin-like FAD_SOX PF18371.1 OQR82133.1 - 0.084 13.2 0.0 0.26 11.7 0.0 1.8 1 1 0 1 1 1 0 Flavin adenine dinucleotide (FAD)-dependent sulfhydryl oxidase PseudoU_synth_1 PF01416.20 OQR82135.1 - 6.2e-15 55.6 0.1 4.2e-12 46.5 0.1 2.9 2 1 0 2 2 2 2 tRNA pseudouridine synthase SBF PF01758.16 OQR82136.1 - 1.8e-36 125.6 17.7 1.8e-36 125.6 17.7 2.8 2 1 1 3 3 3 1 Sodium Bile acid symporter family SBF_like PF13593.6 OQR82136.1 - 2.2e-10 40.4 26.9 2.7e-10 40.1 26.9 1.1 1 0 0 1 1 1 1 SBF-like CPA transporter family (DUF4137) MotA_ExbB PF01618.16 OQR82136.1 - 0.74 9.6 3.7 15 5.3 0.2 2.7 3 0 0 3 3 3 0 MotA/TolQ/ExbB proton channel family ArsC PF03960.15 OQR82137.1 - 4.4e-08 33.0 0.2 5.9e-08 32.6 0.2 1.4 1 1 0 1 1 1 1 ArsC family Glutaredoxin PF00462.24 OQR82137.1 - 0.1 12.8 0.2 0.24 11.7 0.1 1.6 2 0 0 2 2 2 0 Glutaredoxin ThiF PF00899.21 OQR82139.1 - 6.9e-47 159.8 0.0 9.3e-47 159.4 0.0 1.1 1 0 0 1 1 1 1 ThiF family Sacchrp_dh_NADP PF03435.18 OQR82139.1 - 0.013 15.8 1.0 0.44 10.8 1.0 2.5 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain NAD_binding_7 PF13241.6 OQR82139.1 - 0.018 15.5 0.0 0.045 14.2 0.0 1.6 1 1 0 1 1 1 0 Putative NAD(P)-binding 2-Hacid_dh_C PF02826.19 OQR82139.1 - 0.03 13.7 0.0 0.068 12.5 0.0 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain FAD_binding_3 PF01494.19 OQR82139.1 - 0.063 12.5 0.6 0.1 11.8 0.6 1.3 1 0 0 1 1 1 0 FAD binding domain ApbA PF02558.16 OQR82139.1 - 0.1 12.3 0.0 0.19 11.4 0.0 1.6 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA TrkA_N PF02254.18 OQR82139.1 - 0.16 12.2 1.1 0.88 9.8 0.2 2.6 3 1 0 3 3 3 0 TrkA-N domain IQ PF00612.27 OQR82140.1 - 4.2e-29 97.6 54.8 0.00069 19.2 1.6 12.9 12 0 0 12 12 12 9 IQ calmodulin-binding motif TPR_12 PF13424.6 OQR82140.1 - 1.2e-07 31.9 13.0 0.001 19.3 1.0 5.5 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_10 PF13374.6 OQR82140.1 - 9e-07 28.6 14.7 0.011 15.5 0.0 6.4 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_1 PF00515.28 OQR82140.1 - 3e-06 26.8 9.6 0.025 14.4 0.3 4.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 OQR82140.1 - 0.0081 16.2 11.6 0.16 12.2 0.1 5.3 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_7 PF13176.6 OQR82140.1 - 0.037 14.1 1.3 3 8.1 0.1 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat Peptidase_M22 PF00814.25 OQR82141.1 - 2.9e-88 296.1 0.0 3.5e-88 295.8 0.0 1.0 1 0 0 1 1 1 1 Glycoprotease family Thioredoxin PF00085.20 OQR82142.1 - 1.2e-40 137.7 0.0 9.6e-19 67.3 0.0 3.6 4 0 0 4 4 4 3 Thioredoxin Thioredoxin_7 PF13899.6 OQR82142.1 - 8.8e-09 35.4 0.0 0.0013 18.9 0.0 2.5 2 0 0 2 2 2 2 Thioredoxin-like Thioredoxin_8 PF13905.6 OQR82142.1 - 1.2e-08 35.1 0.2 0.13 12.6 0.0 5.3 3 2 2 5 5 5 1 Thioredoxin-like Thioredoxin_2 PF13098.6 OQR82142.1 - 2.3e-08 34.4 0.1 0.2 12.1 0.0 4.0 3 1 0 3 3 3 3 Thioredoxin-like domain OST3_OST6 PF04756.13 OQR82142.1 - 3.5e-08 33.2 0.0 6.2e-06 25.8 0.0 2.1 2 0 0 2 2 2 2 OST3 / OST6 family, transporter family Thioredoxin_6 PF13848.6 OQR82142.1 - 1.2e-07 31.8 0.0 0.0077 16.2 0.0 2.6 3 0 0 3 3 3 2 Thioredoxin-like domain HyaE PF07449.11 OQR82142.1 - 8.4e-05 22.5 0.0 1.1 9.2 0.0 3.2 3 0 0 3 3 3 2 Hydrogenase-1 expression protein HyaE TraF PF13728.6 OQR82142.1 - 0.00026 20.9 0.0 0.11 12.3 0.0 2.8 3 0 0 3 3 3 1 F plasmid transfer operon protein AhpC-TSA PF00578.21 OQR82142.1 - 0.0017 18.3 0.0 0.47 10.4 0.0 2.4 2 0 0 2 2 2 1 AhpC/TSA family Thioredoxin_9 PF14595.6 OQR82142.1 - 0.0044 16.8 0.1 1.3 8.8 0.0 2.6 3 0 0 3 3 3 1 Thioredoxin DUF5004 PF16395.5 OQR82142.1 - 0.034 14.1 0.2 0.073 13.1 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5004) TM_helix PF05552.12 OQR82142.1 - 0.8 9.7 3.8 2 8.4 3.8 1.6 1 0 0 1 1 1 0 Conserved TM helix COPI_assoc PF08507.10 OQR82143.1 - 4.7e-16 59.0 3.2 6.1e-16 58.7 3.2 1.1 1 0 0 1 1 1 1 COPI associated protein YtpI PF14007.6 OQR82143.1 - 0.0021 18.2 5.0 0.016 15.3 0.9 2.3 2 0 0 2 2 2 2 YtpI-like protein S-methyl_trans PF02574.16 OQR82144.1 - 1.2e-52 179.4 0.0 1.6e-52 178.9 0.0 1.2 1 0 0 1 1 1 1 Homocysteine S-methyltransferase Thioredoxin PF00085.20 OQR82144.1 - 1.4e-27 95.7 0.0 4e-27 94.2 0.0 1.8 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 OQR82144.1 - 0.00049 20.5 0.1 0.0041 17.6 0.1 2.4 1 1 0 1 1 1 1 Thioredoxin-like domain TraF PF13728.6 OQR82144.1 - 0.0043 16.9 0.0 0.0074 16.1 0.0 1.3 1 0 0 1 1 1 1 F plasmid transfer operon protein Thioredoxin_8 PF13905.6 OQR82144.1 - 0.094 13.1 0.0 1.5 9.2 0.0 2.6 1 1 1 2 2 2 0 Thioredoxin-like Thioredoxin_7 PF13899.6 OQR82144.1 - 0.1 12.8 0.0 0.29 11.3 0.0 1.8 2 0 0 2 2 2 0 Thioredoxin-like HyaE PF07449.11 OQR82144.1 - 0.17 11.9 0.0 0.35 10.9 0.0 1.4 1 0 0 1 1 1 0 Hydrogenase-1 expression protein HyaE Thioredoxin_9 PF14595.6 OQR82144.1 - 0.17 11.6 0.0 0.31 10.8 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin RabGAP-TBC PF00566.18 OQR82146.1 - 1.7e-34 119.3 0.2 3.3e-34 118.4 0.2 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Ank_5 PF13857.6 OQR82146.1 - 1.9e-06 28.0 0.2 0.00015 22.0 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 OQR82146.1 - 0.00023 21.7 0.0 0.002 18.7 0.0 2.5 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQR82146.1 - 0.00031 21.0 0.0 0.0081 16.6 0.0 3.2 3 0 0 3 3 3 1 Ankyrin repeat Ank_2 PF12796.7 OQR82146.1 - 0.0024 18.4 0.0 0.0057 17.2 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 OQR82146.1 - 0.0068 16.8 0.0 0.059 13.8 0.0 2.6 3 0 0 3 3 3 1 Ankyrin repeat GSHPx PF00255.19 OQR82147.1 - 9.4e-26 89.5 0.2 9.4e-26 89.5 0.2 1.6 2 0 0 2 2 2 1 Glutathione peroxidase PH PF00169.29 OQR82147.1 - 0.047 14.2 0.1 0.1 13.1 0.1 1.6 1 0 0 1 1 1 0 PH domain PH_8 PF15409.6 OQR82147.1 - 0.16 12.2 0.1 0.34 11.2 0.1 1.6 1 0 0 1 1 1 0 Pleckstrin homology domain Citrate_bind PF16114.5 OQR82148.1 - 2.2e-89 297.7 0.0 5.5e-89 296.4 0.0 1.7 2 0 0 2 2 2 1 ATP citrate lyase citrate-binding CoA_binding PF02629.19 OQR82148.1 - 9.1e-09 35.9 0.0 3.1e-08 34.2 0.0 2.0 1 0 0 1 1 1 1 CoA binding domain ATP-grasp_2 PF08442.10 OQR82148.1 - 0.00064 19.3 0.0 0.0012 18.4 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain Ligase_CoA PF00549.19 OQR82148.1 - 0.0016 18.3 0.0 0.0031 17.4 0.0 1.5 1 0 0 1 1 1 1 CoA-ligase FAP PF07174.11 OQR82148.1 - 1.4 8.3 11.5 2.1 7.7 11.5 1.2 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) Pkinase_Tyr PF07714.17 OQR82149.1 - 1.9e-50 171.6 0.0 2.3e-50 171.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OQR82149.1 - 2.4e-47 161.6 0.0 3.4e-47 161.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 OQR82149.1 - 0.00062 19.2 0.0 0.001 18.5 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 OQR82149.1 - 0.00075 18.4 0.0 0.002 17.0 0.0 1.6 2 0 0 2 2 2 1 Fungal protein kinase Metallophos PF00149.28 OQR82150.1 - 8e-24 85.3 0.5 1.9e-23 84.0 0.5 1.7 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_C PF14008.6 OQR82150.1 - 1e-16 61.5 0.1 5.1e-16 59.3 0.0 2.4 2 0 0 2 2 2 1 Iron/zinc purple acid phosphatase-like protein C Pur_ac_phosph_N PF16656.5 OQR82150.1 - 1.5e-11 44.7 1.6 1.5e-11 44.7 1.6 2.7 3 0 0 3 3 3 1 Purple acid Phosphatase, N-terminal domain MFS_2 PF13347.6 OQR82151.1 - 0.0012 17.5 1.3 0.0012 17.5 1.3 3.0 2 1 0 2 2 2 1 MFS/sugar transport protein DUF423 PF04241.15 OQR82151.1 - 0.12 12.6 3.5 0.15 12.3 0.2 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF423) Med18 PF09637.10 OQR82151.1 - 0.13 12.1 0.0 0.2 11.5 0.0 1.3 1 0 0 1 1 1 0 Med18 protein LRR_6 PF13516.6 OQR82155.1 - 2.1e-10 39.8 1.6 0.043 13.9 0.0 6.9 7 0 0 7 7 7 3 Leucine Rich repeat LRR_4 PF12799.7 OQR82155.1 - 0.00012 22.4 2.7 1.9 9.1 0.1 4.5 2 2 3 5 5 5 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 OQR82155.1 - 1.8 9.4 11.9 2.2e+02 3.1 0.1 6.2 7 1 0 7 7 7 0 Leucine Rich Repeat NEMP PF10225.9 OQR82156.1 - 4.2e-14 52.8 18.8 7e-09 35.7 0.0 3.2 3 0 0 3 3 3 2 NEMP family DUF1461 PF07314.11 OQR82156.1 - 0.11 12.4 0.1 0.11 12.4 0.1 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1461) PSII_Pbs27 PF13326.6 OQR82156.1 - 1.3 9.3 6.1 0.71 10.2 0.7 2.7 2 1 0 3 3 3 0 Photosystem II Pbs27 DUF1727 PF08353.10 OQR82156.1 - 1.3 8.9 3.7 7.8 6.5 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1727) PCI PF01399.27 OQR82158.1 - 6.7e-15 55.5 0.4 1.8e-14 54.1 0.0 1.9 2 0 0 2 2 2 1 PCI domain Ser_hydrolase PF06821.13 OQR82158.1 - 1.5e-10 41.2 0.1 1.4e-09 38.0 0.0 2.4 3 0 0 3 3 3 1 Serine hydrolase DUF1057 PF06342.12 OQR82158.1 - 0.00069 18.7 0.0 0.0016 17.5 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1057) Abhydrolase_6 PF12697.7 OQR82158.1 - 0.0067 17.0 0.0 0.012 16.2 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.7 OQR82158.1 - 0.043 13.6 0.0 0.082 12.7 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 OQR82158.1 - 0.16 11.6 0.0 0.27 10.8 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold Pkinase PF00069.25 OQR82159.1 - 2.3e-72 243.6 0.0 4.5e-72 242.6 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQR82159.1 - 2.7e-35 121.9 0.0 4.5e-35 121.2 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase SAM_2 PF07647.17 OQR82159.1 - 4.7e-09 36.2 0.1 1.1e-08 35.0 0.1 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 OQR82159.1 - 7.4e-08 32.7 0.1 1.6e-07 31.6 0.1 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Kinase-like PF14531.6 OQR82159.1 - 2.4e-05 23.8 0.0 4.5e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 OQR82159.1 - 0.00066 19.1 0.2 0.0015 17.9 0.2 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 OQR82159.1 - 0.002 17.0 1.0 0.0051 15.7 0.0 1.9 2 0 0 2 2 2 1 Fungal protein kinase NleF_casp_inhib PF16809.5 OQR82159.1 - 0.0027 17.6 1.9 0.0062 16.4 1.9 1.6 1 0 0 1 1 1 1 NleF caspase inhibitor RIO1 PF01163.22 OQR82159.1 - 0.0033 17.0 0.3 0.011 15.4 0.0 2.0 2 0 0 2 2 2 1 RIO1 family APH PF01636.23 OQR82159.1 - 0.021 14.7 1.1 1.2 9.0 0.1 3.0 3 1 1 4 4 4 0 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.11 OQR82159.1 - 0.03 13.3 0.1 0.047 12.7 0.1 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase DUF484 PF04340.12 OQR82159.1 - 0.031 14.0 2.8 0.056 13.1 2.8 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF484 FliJ PF02050.16 OQR82159.1 - 0.094 12.9 7.4 0.25 11.6 7.4 1.7 1 0 0 1 1 1 0 Flagellar FliJ protein FapA PF03961.13 OQR82159.1 - 0.11 11.1 4.0 0.17 10.4 4.0 1.3 1 0 0 1 1 1 0 Flagellar Assembly Protein A SpecificRecomb PF10136.9 OQR82159.1 - 0.33 9.2 1.7 0.51 8.6 1.7 1.2 1 0 0 1 1 1 0 Site-specific recombinase Lebercilin PF15619.6 OQR82159.1 - 1 9.0 13.6 2.1 7.9 13.6 1.4 1 0 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease FAM76 PF16046.5 OQR82159.1 - 5.3 6.3 8.8 8 5.7 8.8 1.2 1 0 0 1 1 1 0 FAM76 protein DUF1664 PF07889.12 OQR82159.1 - 8.7 6.4 7.8 9.1 6.3 1.4 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) TMPIT PF07851.13 OQR82159.1 - 9.3 5.4 12.5 0.93 8.7 2.5 3.0 2 1 1 3 3 3 0 TMPIT-like protein adh_short_C2 PF13561.6 OQR82161.1 - 5.2e-54 183.3 0.9 1.5e-53 181.8 0.9 1.7 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OQR82161.1 - 2e-42 144.9 4.1 9.6e-42 142.7 4.1 1.8 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OQR82161.1 - 2.8e-06 27.4 2.5 3e-05 24.0 0.5 2.2 2 0 0 2 2 2 1 KR domain Epimerase PF01370.21 OQR82161.1 - 0.0009 18.8 0.5 0.003 17.1 0.5 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DAHP_synth_1 PF00793.20 OQR82162.1 - 1.2e-96 322.8 0.0 1.6e-96 322.4 0.0 1.1 1 0 0 1 1 1 1 DAHP synthetase I family HSP70 PF00012.20 OQR82163.1 - 9.4e-61 205.7 4.1 4.5e-59 200.2 0.6 2.2 1 1 1 2 2 2 2 Hsp70 protein TPR_1 PF00515.28 OQR82163.1 - 6.5e-12 44.7 8.4 3.2e-05 23.5 0.2 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 OQR82163.1 - 1.2e-11 43.7 8.4 1.4e-05 24.9 0.3 4.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 OQR82163.1 - 4.1e-09 35.9 4.7 0.0015 18.6 0.1 3.4 2 0 0 2 2 2 2 Tetratricopeptide repeat MreB_Mbl PF06723.13 OQR82163.1 - 7.2e-05 21.7 3.7 0.00011 21.1 2.3 2.0 2 1 1 3 3 3 1 MreB/Mbl protein TPR_19 PF14559.6 OQR82163.1 - 0.00016 22.1 5.8 0.0011 19.4 1.8 3.0 1 1 1 2 2 2 2 Tetratricopeptide repeat ANAPC3 PF12895.7 OQR82163.1 - 0.00024 21.3 6.9 0.00071 19.8 6.9 1.9 1 1 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.6 OQR82163.1 - 0.00042 20.4 0.4 0.0022 18.1 0.4 2.3 1 1 1 2 2 2 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 OQR82163.1 - 0.0014 18.7 6.2 0.015 15.4 1.4 3.0 1 1 1 2 2 2 1 Fis1 C-terminal tetratricopeptide repeat Ubiq_cyt_C_chap PF03981.12 OQR82163.1 - 0.0018 18.4 0.3 0.0079 16.3 0.3 2.1 1 0 0 1 1 1 1 Ubiquinol-cytochrome C chaperone TPR_6 PF13174.6 OQR82163.1 - 0.0021 18.6 3.7 0.56 11.0 0.4 3.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 OQR82163.1 - 0.0054 17.0 11.5 0.026 14.8 0.6 3.4 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.6 OQR82163.1 - 0.0082 16.5 5.8 0.08 13.4 0.9 3.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 OQR82163.1 - 0.012 16.3 4.1 0.16 12.6 0.5 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.6 OQR82163.1 - 0.024 14.6 9.1 0.047 13.7 0.2 3.8 4 0 0 4 4 3 0 Tetratricopeptide repeat ANAPC5 PF12862.7 OQR82163.1 - 0.077 13.1 1.7 0.91 9.6 0.7 2.8 1 1 1 2 2 2 0 Anaphase-promoting complex subunit 5 TPR_11 PF13414.6 OQR82163.1 - 0.08 12.6 8.7 0.59 9.9 1.1 3.8 3 1 1 4 4 3 0 TPR repeat Terminase_4 PF05119.12 OQR82163.1 - 0.081 13.4 0.3 1.3 9.4 0.0 2.9 2 1 1 3 3 3 0 Phage terminase, small subunit TPR_14 PF13428.6 OQR82163.1 - 0.092 13.6 0.4 0.092 13.6 0.4 4.4 4 1 1 5 5 4 0 Tetratricopeptide repeat TUDOR PF00567.24 OQR82164.1 - 6.4e-05 23.0 0.0 0.00017 21.6 0.0 1.7 2 0 0 2 2 2 1 Tudor domain HNH PF01844.23 OQR82164.1 - 0.013 15.6 4.0 0.033 14.4 2.8 2.2 2 1 0 2 2 2 0 HNH endonuclease SMN PF06003.12 OQR82164.1 - 0.028 13.7 0.0 0.041 13.2 0.0 1.2 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) CTV_P23 PF04808.12 OQR82164.1 - 0.14 11.7 0.3 0.23 11.0 0.3 1.3 1 0 0 1 1 1 0 Citrus tristeza virus (CTV) P23 protein Aminotran_1_2 PF00155.21 OQR82165.1 - 1.1e-84 284.7 0.0 1.3e-84 284.4 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Thioredoxin_4 PF13462.6 OQR82165.1 - 2.8e-07 30.8 0.0 5.8e-07 29.8 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin DSBA PF01323.20 OQR82165.1 - 0.00011 22.0 0.0 0.015 15.1 0.0 2.5 2 0 0 2 2 2 2 DSBA-like thioredoxin domain RSN1_7TM PF02714.15 OQR82166.1 - 4.1e-31 108.3 20.3 7.1e-31 107.5 20.3 1.4 1 0 0 1 1 1 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 OQR82166.1 - 1.5e-13 50.8 4.5 1.5e-13 50.8 4.5 4.6 4 2 1 5 5 5 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 OQR82166.1 - 2e-05 24.9 0.1 0.00041 20.6 0.1 2.8 1 1 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter CCSMST1 PF15013.6 OQR82166.1 - 0.24 11.6 2.9 2.6 8.3 0.0 3.4 3 0 0 3 3 3 0 CCSMST1 family P5-ATPase PF12409.8 OQR82166.1 - 1.2 9.3 3.4 1.9 8.6 0.0 2.8 3 0 0 3 3 3 0 P5-type ATPase cation transporter Comm PF15957.5 OQR82166.1 - 2 8.8 5.8 11 6.4 0.4 3.2 2 1 0 2 2 2 0 Commissureless TMEM18 PF14770.6 OQR82166.1 - 7.5 6.6 10.5 1.5 8.8 2.0 3.3 3 0 0 3 3 3 0 Transmembrane protein 18 PPR_2 PF13041.6 OQR82167.1 - 2e-32 111.1 9.7 8.8e-14 51.4 0.7 4.6 1 1 3 4 4 4 4 PPR repeat family Methyltransf_4 PF02390.17 OQR82167.1 - 4.9e-20 71.7 0.4 1.1e-19 70.5 0.0 1.8 2 0 0 2 2 2 1 Putative methyltransferase PPR PF01535.20 OQR82167.1 - 1.2e-19 69.1 5.5 5.7e-05 23.1 0.1 5.6 5 0 0 5 5 5 4 PPR repeat PPR_3 PF13812.6 OQR82167.1 - 1.6e-16 60.1 2.9 5.5e-08 32.8 0.2 3.5 2 1 1 3 3 3 2 Pentatricopeptide repeat domain PPR_1 PF12854.7 OQR82167.1 - 7.9e-16 57.5 1.0 1.5e-08 34.2 0.0 4.4 4 0 0 4 4 4 3 PPR repeat PPR_long PF17177.4 OQR82167.1 - 8.2e-10 38.4 1.5 1.6e-08 34.2 0.6 2.4 1 1 1 2 2 2 1 Pentacotripeptide-repeat region of PRORP TPR_19 PF14559.6 OQR82167.1 - 0.00028 21.3 0.0 0.32 11.6 0.0 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat NIF3 PF01784.18 OQR82167.1 - 0.029 14.0 0.0 0.046 13.3 0.0 1.4 1 0 0 1 1 1 0 NIF3 (NGG1p interacting factor 3) MTS PF05175.14 OQR82167.1 - 0.039 13.5 0.0 0.1 12.2 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase small domain RPM2 PF08579.11 OQR82167.1 - 0.23 11.9 1.8 6 7.3 0.2 3.3 3 0 0 3 3 3 0 Mitochondrial ribonuclease P subunit (RPM2) Pkinase PF00069.25 OQR82168.1 - 3.6e-53 180.6 0.0 5.1e-53 180.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQR82168.1 - 1.1e-51 175.6 0.0 1.5e-51 175.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase LRR_4 PF12799.7 OQR82168.1 - 1.5e-05 25.2 9.1 0.072 13.5 1.8 5.1 4 2 1 5 5 5 2 Leucine Rich repeats (2 copies) Pkinase_fungal PF17667.1 OQR82168.1 - 0.00015 20.7 0.2 0.00021 20.2 0.2 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 OQR82168.1 - 0.0011 18.4 0.1 0.0017 17.7 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family FNIP PF05725.12 OQR82168.1 - 0.0018 18.4 7.1 0.36 11.0 0.0 4.7 4 1 2 6 6 6 1 FNIP Repeat APH PF01636.23 OQR82168.1 - 0.029 14.3 0.0 0.049 13.5 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family LRR_8 PF13855.6 OQR82168.1 - 0.12 12.2 4.7 0.92 9.3 0.4 3.6 2 1 2 4 4 4 0 Leucine rich repeat Nuc_deoxyri_tr2 PF15891.5 OQR82169.1 - 2e-28 98.8 0.0 1.1e-20 74.0 0.0 2.6 2 0 0 2 2 2 2 Nucleoside 2-deoxyribosyltransferase like Isy1 PF06246.12 OQR82169.1 - 0.11 12.1 0.1 6.8 6.2 0.1 2.2 1 1 1 2 2 2 0 Isy1-like splicing family Dzip-like_N PF13815.6 OQR82170.1 - 2.9e-33 114.3 9.1 2.9e-33 114.3 9.1 4.9 5 0 0 5 5 5 1 Iguana/Dzip1-like DAZ-interacting protein N-terminal IQ PF00612.27 OQR82170.1 - 6.9e-06 25.4 6.6 0.0027 17.3 0.2 3.7 3 0 0 3 3 3 2 IQ calmodulin-binding motif zf-C2H2_4 PF13894.6 OQR82170.1 - 0.12 13.3 1.1 0.51 11.3 1.1 2.1 1 0 0 1 1 1 0 C2H2-type zinc finger zf-Di19 PF05605.12 OQR82170.1 - 0.12 12.7 0.5 0.4 11.0 0.5 2.0 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_jaz PF12171.8 OQR82170.1 - 0.27 11.6 2.8 0.97 9.8 2.8 2.0 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding ApoO PF09769.9 OQR82170.1 - 0.81 9.7 5.2 2 8.4 0.6 2.7 2 0 0 2 2 2 0 Apolipoprotein O Voldacs PF03517.13 OQR82171.1 - 2.1e-20 73.3 2.9 1.1e-10 41.8 0.1 2.2 1 1 1 2 2 2 2 Regulator of volume decrease after cellular swelling Vps36_ESCRT-II PF11605.8 OQR82171.1 - 0.0012 18.9 0.0 0.0024 18.0 0.0 1.5 1 0 0 1 1 1 1 Vacuolar protein sorting protein 36 Vps36 BBL5 PF07289.11 OQR82171.1 - 0.027 13.5 0.0 0.03 13.4 0.0 1.2 1 0 0 1 1 1 0 Bardet-Biedl syndrome 5 protein PH_TFIIH PF08567.11 OQR82171.1 - 0.098 13.0 0.0 0.16 12.3 0.0 1.4 1 0 0 1 1 1 0 TFIIH p62 subunit, N-terminal domain CCT PF06203.14 OQR82172.1 - 0.014 15.4 5.1 0.13 12.4 4.4 2.1 2 0 0 2 2 2 0 CCT motif FIN1 PF17300.2 OQR82172.1 - 0.025 14.1 1.5 0.036 13.6 1.5 1.3 1 0 0 1 1 1 0 Filaments in between nuclei protein-1 DUF4442 PF14539.6 OQR82173.1 - 1.6e-29 102.7 0.1 1.9e-29 102.5 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4442) Med28 PF11594.8 OQR82177.1 - 0.11 12.6 0.0 0.16 12.0 0.0 1.3 1 0 0 1 1 1 0 Mediator complex subunit 28 Ank_2 PF12796.7 OQR82178.1 - 5.2e-19 68.6 5.0 1.2e-09 38.6 0.1 3.6 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OQR82178.1 - 4.1e-17 62.0 3.8 0.0033 17.7 0.1 6.3 2 1 4 6 6 6 5 Ankyrin repeats (many copies) Ank_4 PF13637.6 OQR82178.1 - 3.7e-14 52.9 3.6 0.011 16.3 0.1 5.2 3 3 1 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQR82178.1 - 3.4e-10 39.3 2.7 0.95 10.2 0.0 6.8 7 0 0 7 7 7 3 Ankyrin repeat Ank PF00023.30 OQR82178.1 - 1.3e-06 28.5 0.8 1.8 9.2 0.0 5.2 3 2 2 5 5 5 2 Ankyrin repeat DUF5049 PF16468.5 OQR82178.1 - 0.0018 18.2 1.4 19 5.3 0.0 5.3 3 2 3 6 6 6 1 Domain of unknown function (DUF5049) DUF1843 PF08898.10 OQR82178.1 - 0.0071 16.8 0.1 0.53 10.8 0.0 3.3 4 0 0 4 4 4 1 Domain of unknown function (DUF1843) OrfB_Zn_ribbon PF07282.11 OQR82181.1 - 0.011 15.7 4.3 0.03 14.2 4.3 1.7 1 0 0 1 1 1 0 Putative transposase DNA-binding domain YhfH PF14149.6 OQR82181.1 - 0.014 15.3 4.3 0.12 12.3 0.2 2.5 2 0 0 2 2 2 0 YhfH-like protein Zn_Tnp_IS91 PF14319.6 OQR82181.1 - 0.017 15.2 1.2 0.065 13.3 1.2 2.0 1 0 0 1 1 1 0 Transposase zinc-binding domain Lar_restr_allev PF14354.6 OQR82181.1 - 0.044 14.2 0.8 0.12 12.8 0.8 1.7 1 0 0 1 1 1 0 Restriction alleviation protein Lar zf-Mss51 PF13824.6 OQR82181.1 - 0.072 13.2 3.3 0.64 10.2 3.4 2.5 1 1 1 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 DZR PF12773.7 OQR82181.1 - 0.096 12.7 1.8 0.21 11.6 1.8 1.5 1 0 0 1 1 1 0 Double zinc ribbon Zn_Tnp_IS1595 PF12760.7 OQR82181.1 - 0.12 12.3 5.0 0.57 10.2 4.9 2.1 1 1 1 2 2 2 0 Transposase zinc-ribbon domain Ribosomal_S27 PF01599.19 OQR82181.1 - 0.26 11.5 7.6 0.91 9.7 1.0 2.8 1 1 1 2 2 2 0 Ribosomal protein S27a zf-C2H2_3 PF13878.6 OQR82181.1 - 0.31 10.9 3.0 0.84 9.5 0.2 2.6 2 0 0 2 2 2 0 zinc-finger of acetyl-transferase ESCO zf-ribbon_3 PF13248.6 OQR82181.1 - 0.32 10.5 6.2 2.8 7.5 0.5 2.5 2 0 0 2 2 2 0 zinc-ribbon domain TF_Zn_Ribbon PF08271.12 OQR82181.1 - 0.38 10.3 1.5 12 5.6 0.0 2.5 2 0 0 2 2 2 0 TFIIB zinc-binding Zn-ribbon_8 PF09723.10 OQR82181.1 - 1.4 9.1 5.2 11 6.2 0.4 2.4 1 1 1 2 2 2 0 Zinc ribbon domain zinc_ribbon_2 PF13240.6 OQR82181.1 - 2.3 8.0 7.9 42 4.1 7.9 2.4 1 1 0 1 1 1 0 zinc-ribbon domain zf-tcix PF14952.6 OQR82181.1 - 3.7 7.2 7.4 7.4 6.3 0.8 2.4 2 0 0 2 2 2 0 Putative treble-clef, zinc-finger, Zn-binding FYVE PF01363.21 OQR82182.1 - 1.3e-31 108.6 33.2 6.9e-17 61.4 9.1 3.7 3 0 0 3 3 3 2 FYVE zinc finger RhoGEF PF00621.20 OQR82182.1 - 9e-26 91.2 4.4 1.1e-24 87.7 4.4 2.3 1 1 0 1 1 1 1 RhoGEF domain PH PF00169.29 OQR82182.1 - 1.1e-16 61.3 14.4 0.00054 20.4 0.0 5.1 5 1 0 5 5 5 4 PH domain PH_11 PF15413.6 OQR82182.1 - 1.7e-05 25.2 15.0 0.72 10.3 0.0 5.0 4 1 0 4 4 4 3 Pleckstrin homology domain PH_13 PF16652.5 OQR82182.1 - 0.00049 19.9 8.0 0.075 12.8 0.3 4.6 5 1 0 5 5 5 2 Pleckstrin homology domain PH_9 PF15410.6 OQR82182.1 - 0.18 12.2 12.9 0.42 11.0 0.9 5.0 4 2 2 6 6 6 0 Pleckstrin homology domain PH_16 PF17838.1 OQR82182.1 - 2.7 7.9 5.8 27 4.6 0.1 4.6 5 1 0 5 5 5 0 PH domain Siva PF05458.12 OQR82182.1 - 9.6 5.9 18.0 2.8 7.6 3.6 2.5 2 0 0 2 2 2 0 Cd27 binding protein (Siva) fn3 PF00041.21 OQR82183.1 - 9.7e-107 349.5 118.2 6.3e-10 39.3 0.1 33.6 32 0 0 32 32 32 23 Fibronectin type III domain PA14 PF07691.12 OQR82183.1 - 5.1e-57 191.8 5.1 1.5e-23 83.2 0.1 4.7 4 0 0 4 4 4 3 PA14 domain Filamin PF00630.19 OQR82183.1 - 1.3e-34 119.1 0.0 3.8e-06 27.7 0.0 10.0 9 1 0 9 9 8 5 Filamin/ABP280 repeat Pur_ac_phosph_N PF16656.5 OQR82183.1 - 1.2e-12 48.2 75.1 6.9e-05 23.3 0.1 18.0 20 1 0 20 20 19 4 Purple acid Phosphatase, N-terminal domain DUF2369 PF10179.9 OQR82183.1 - 7.5e-06 26.2 15.0 1.7 9.1 0.0 10.0 11 0 0 11 11 10 1 Uncharacterised conserved protein (DUF2369) GLEYA PF10528.9 OQR82183.1 - 0.0011 19.3 24.7 0.0018 18.6 0.1 8.2 7 0 0 7 7 7 2 GLEYA domain fn3_4 PF16794.5 OQR82183.1 - 0.0051 16.7 0.0 20 5.1 0.0 5.3 5 0 0 5 5 4 0 Fibronectin-III type domain POTRA_1 PF08478.10 OQR82183.1 - 0.0072 16.6 0.0 45 4.4 0.0 5.9 6 0 0 6 6 6 0 POTRA domain, FtsQ-type SPDY PF03771.16 OQR82183.1 - 0.27 11.2 3.6 12 5.9 0.0 5.6 5 0 0 5 5 5 0 Domain of unknown function (DUF317) HTH_41 PF14502.6 OQR82183.1 - 0.37 10.5 7.5 20 5.0 0.0 6.0 8 0 0 8 8 8 0 Helix-turn-helix domain NAR2 PF16974.5 OQR82183.1 - 4 6.8 20.6 9.6 5.6 0.1 7.9 10 0 0 10 10 10 0 High-affinity nitrate transporter accessory MG4 PF17789.1 OQR82183.1 - 6.3 7.0 10.0 51 4.1 0.0 6.1 7 0 0 7 7 7 0 Macroglobulin domain MG4 DHHC PF01529.20 OQR82184.1 - 7.7e-35 119.9 14.4 7.7e-35 119.9 14.4 2.8 3 1 0 3 3 3 1 DHHC palmitoyltransferase MPC PF03650.13 OQR82184.1 - 0.22 11.7 1.3 0.26 11.5 0.1 1.7 2 0 0 2 2 2 0 Mitochondrial pyruvate carriers IGFBP PF00219.18 OQR82184.1 - 0.58 10.8 6.6 1.4 9.6 6.6 1.6 1 0 0 1 1 1 0 Insulin-like growth factor binding protein UDPGP PF01704.18 OQR82185.1 - 2.4e-171 570.0 0.2 2.7e-171 569.8 0.2 1.0 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase DUF4301 PF14134.6 OQR82185.1 - 0.099 11.4 0.2 1.1 8.0 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4301) Peptidase_C48 PF02902.19 OQR82186.1 - 1.7e-14 54.2 1.0 3.8e-14 53.0 1.0 1.6 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Peptidase_S28 PF05577.12 OQR82188.1 - 8.7e-96 321.4 0.2 1e-95 321.1 0.2 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase S28 Abhydrolase_1 PF00561.20 OQR82188.1 - 0.00061 19.5 0.0 0.0011 18.6 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S37 PF05576.11 OQR82188.1 - 0.0012 17.6 0.1 0.0019 16.9 0.1 1.3 1 0 0 1 1 1 1 PS-10 peptidase S37 Peptidase_S9 PF00326.21 OQR82188.1 - 0.0024 17.4 0.0 0.0048 16.4 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Peptidase_S28 PF05577.12 OQR82189.1 - 8.1e-192 637.8 9.9 9.5e-99 331.1 2.7 2.0 2 0 0 2 2 2 2 Serine carboxypeptidase S28 Peptidase_S37 PF05576.11 OQR82189.1 - 1.1e-10 40.8 1.5 0.00024 19.9 0.1 2.3 2 0 0 2 2 2 2 PS-10 peptidase S37 Peptidase_S9 PF00326.21 OQR82189.1 - 1.6e-08 34.3 0.3 0.00025 20.6 0.0 2.5 2 0 0 2 2 2 2 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 OQR82189.1 - 4.1e-06 26.2 0.4 0.061 12.6 0.1 2.4 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 OQR82189.1 - 7.6e-06 25.8 1.6 0.0065 16.1 0.1 2.9 3 0 0 3 3 3 2 alpha/beta hydrolase fold DUF1505 PF07403.11 OQR82189.1 - 0.0022 18.2 6.5 0.28 11.4 1.2 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF1505) HEAT_PBS PF03130.16 OQR82189.1 - 0.042 14.5 0.0 24 6.0 0.0 3.2 2 0 0 2 2 2 0 PBS lyase HEAT-like repeat ThiW PF09512.10 OQR82189.1 - 0.18 11.9 0.4 33 4.6 0.0 2.8 3 0 0 3 3 3 0 Thiamine-precursor transporter protein (ThiW) Pkinase PF00069.25 OQR82190.1 - 1.4e-44 152.4 0.0 1.8e-44 152.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQR82190.1 - 3.6e-36 124.8 0.0 4.3e-36 124.5 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OQR82190.1 - 2.5e-05 23.3 0.1 3.5e-05 22.8 0.1 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 OQR82190.1 - 3.5e-05 23.2 0.1 5.9e-05 22.5 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 OQR82190.1 - 6.5e-05 22.4 0.0 8.2e-05 22.1 0.0 1.2 1 0 0 1 1 1 1 Kinase-like FTA2 PF13095.6 OQR82190.1 - 0.012 15.2 0.2 0.29 10.7 0.0 2.2 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 ANF_receptor PF01094.28 OQR82190.1 - 0.075 12.1 0.0 0.26 10.4 0.0 1.7 2 0 0 2 2 2 0 Receptor family ligand binding region GBP PF02263.19 OQR82191.1 - 8.4e-06 25.2 0.0 3.1e-05 23.4 0.0 1.9 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain MMR_HSR1 PF01926.23 OQR82191.1 - 2.3e-05 24.4 0.0 9.5e-05 22.5 0.0 2.1 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 OQR82191.1 - 0.00018 21.6 0.2 0.0019 18.3 0.1 2.6 1 1 1 2 2 2 1 Dynamin family DUF2497 PF10691.9 OQR82191.1 - 0.085 13.3 0.1 3.3 8.2 0.0 3.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2497) Abi_2 PF07751.11 OQR82191.1 - 2 8.7 6.3 0.53 10.5 1.9 2.3 2 0 0 2 2 2 0 Abi-like protein RhgB_N PF09284.10 OQR82193.1 - 1.9e-61 207.8 1.3 2.2e-61 207.6 1.3 1.0 1 0 0 1 1 1 1 Rhamnogalacturonan lyase B, N-terminal TraO PF10626.9 OQR82193.1 - 0.077 12.8 0.1 0.13 12.0 0.1 1.4 1 0 0 1 1 1 0 Conjugative transposon protein TraO CCDC53 PF10152.9 OQR82194.1 - 0.029 14.8 3.7 0.085 13.3 3.7 1.8 1 1 0 1 1 1 0 Subunit CCDC53 of WASH complex YscJ_FliF_C PF08345.11 OQR82194.1 - 0.031 14.6 1.8 0.047 14.0 1.8 1.3 1 0 0 1 1 1 0 Flagellar M-ring protein C-terminal DUF1056 PF06341.11 OQR82194.1 - 1.6 9.1 5.1 12 6.3 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1056) B56 PF01603.20 OQR82195.1 - 6.3e-16 58.4 0.9 7.3e-16 58.2 0.1 1.5 2 0 0 2 2 2 1 Protein phosphatase 2A regulatory B subunit (B56 family) PPIP5K2_N PF18086.1 OQR82196.1 - 0.0049 17.0 0.6 0.019 15.1 0.1 2.2 2 0 0 2 2 2 1 Diphosphoinositol pentakisphosphate kinase 2 N-terminal domain HBD PF18534.1 OQR82196.1 - 0.11 12.7 0.6 0.25 11.5 0.1 1.8 2 0 0 2 2 2 0 Helical bundle domain ubiquitin PF00240.23 OQR82196.1 - 0.11 12.2 0.0 0.43 10.4 0.0 2.0 1 1 0 1 1 1 0 Ubiquitin family Abhydrolase_1 PF00561.20 OQR82197.1 - 1.4e-19 70.8 0.0 2.6e-18 66.6 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 OQR82197.1 - 7.1e-14 52.9 0.0 8.9e-14 52.6 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 OQR82197.1 - 1e-12 47.9 0.0 2.9e-07 30.0 0.1 3.0 2 1 1 3 3 3 2 Serine aminopeptidase, S33 DLH PF01738.18 OQR82197.1 - 0.0018 17.9 0.0 0.26 10.8 0.0 2.3 2 1 0 2 2 2 2 Dienelactone hydrolase family Thioesterase PF00975.20 OQR82197.1 - 0.013 15.7 0.0 0.019 15.0 0.0 1.2 1 0 0 1 1 1 0 Thioesterase domain Abhydrolase_4 PF08386.10 OQR82197.1 - 0.029 14.5 0.0 0.065 13.3 0.0 1.6 1 0 0 1 1 1 0 TAP-like protein Peptidase_S15 PF02129.18 OQR82197.1 - 0.097 12.2 0.0 0.21 11.1 0.0 1.5 1 1 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) Esterase PF00756.20 OQR82197.1 - 0.14 11.8 0.0 0.19 11.3 0.0 1.2 1 0 0 1 1 1 0 Putative esterase Abhydrolase_1 PF00561.20 OQR82198.1 - 2.9e-22 79.6 0.0 1.7e-21 77.0 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 OQR82198.1 - 7.1e-13 48.4 0.1 9.8e-13 47.9 0.1 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 OQR82198.1 - 2.4e-12 47.9 0.0 3e-12 47.6 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.18 OQR82198.1 - 0.02 14.4 0.0 4.7 6.7 0.0 2.2 2 0 0 2 2 2 0 Dienelactone hydrolase family Thioesterase PF00975.20 OQR82198.1 - 0.1 12.7 0.0 0.19 11.8 0.0 1.4 1 0 0 1 1 1 0 Thioesterase domain Asp-B-Hydro_N PF05279.11 OQR82201.1 - 0.0032 17.6 0.0 0.0034 17.5 0.0 1.1 1 0 0 1 1 1 1 Aspartyl beta-hydroxylase N-terminal region SoDot-IcmSS PF16848.5 OQR82201.1 - 0.078 12.9 0.0 0.078 12.9 0.0 1.1 1 0 0 1 1 1 0 Substrate of the Dot/Icm secretion system, putative DUF4203 PF13886.6 OQR82202.1 - 3.1e-53 180.4 53.3 3.9e-29 101.8 23.0 2.1 2 0 0 2 2 2 2 Domain of unknown function (DUF4203) DUF4203 PF13886.6 OQR82203.1 - 1.2e-11 44.6 5.8 1.4e-11 44.5 5.8 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4203) DUF308 PF03729.13 OQR82203.1 - 0.088 13.1 7.4 0.45 10.9 7.5 2.0 1 1 1 2 2 2 0 Short repeat of unknown function (DUF308) PRKCSH-like PF12999.7 OQR82204.1 - 3.2e-34 118.2 1.3 3.2e-34 118.2 1.3 1.9 2 0 0 2 2 2 1 Glucosidase II beta subunit-like PRKCSH_1 PF13015.6 OQR82204.1 - 1.6e-31 109.1 0.2 4.4e-31 107.6 0.2 1.8 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein PRKCSH PF07915.13 OQR82204.1 - 0.0022 18.9 0.4 0.0094 16.9 0.1 2.3 2 0 0 2 2 2 1 Glucosidase II beta subunit-like protein ATG27 PF09451.10 OQR82204.1 - 0.0069 16.3 0.5 0.013 15.4 0.5 1.5 1 0 0 1 1 1 1 Autophagy-related protein 27 Ldl_recept_a PF00057.18 OQR82204.1 - 0.52 10.6 16.3 2.8 8.2 5.5 2.9 1 1 1 2 2 2 0 Low-density lipoprotein receptor domain class A Sacchrp_dh_NADP PF03435.18 OQR82204.1 - 0.58 10.4 7.0 11 6.3 0.3 3.2 3 0 0 3 3 3 0 Saccharopine dehydrogenase NADP binding domain DUF4203 PF13886.6 OQR82205.1 - 3e-05 23.8 1.0 3.6e-05 23.5 1.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4203) Pkinase PF00069.25 OQR82206.1 - 1e-08 34.9 0.0 1.8e-08 34.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 OQR82206.1 - 0.0076 15.6 0.0 0.0094 15.3 0.0 1.1 1 0 0 1 1 1 1 Kinase-like COMM_domain PF07258.14 OQR82207.1 - 0.013 15.6 0.1 0.022 14.9 0.1 1.4 1 0 0 1 1 1 0 COMM domain DUF4203 PF13886.6 OQR82209.1 - 3.8e-121 402.2 126.2 6.7e-42 143.4 33.4 3.5 4 0 0 4 4 4 3 Domain of unknown function (DUF4203) DUF3270 PF11674.8 OQR82209.1 - 0.089 13.0 1.0 0.75 10.0 0.0 3.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3270) DUF4176 PF13780.6 OQR82210.1 - 0.016 15.2 0.0 0.022 14.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4176) Robl_LC7 PF03259.17 OQR82211.1 - 3e-06 26.9 0.1 1.7e-05 24.5 0.1 1.9 1 1 0 1 1 1 1 Roadblock/LC7 domain CooT PF10133.9 OQR82212.1 - 0.043 14.1 0.3 0.064 13.5 0.3 1.4 1 0 0 1 1 1 0 CO dehydrogenase accessory protein CooT POC1 PF10450.9 OQR82212.1 - 0.11 11.4 0.0 0.12 11.3 0.0 1.0 1 0 0 1 1 1 0 POC1 chaperone Tmemb_161AB PF10268.9 OQR82213.1 - 1.8e-39 135.7 3.2 2.4e-39 135.3 3.2 1.1 1 0 0 1 1 1 1 Predicted transmembrane protein 161AB Methyltransf_16 PF10294.9 OQR82217.1 - 8.5e-17 61.4 0.0 1.1e-16 61.0 0.0 1.1 1 0 0 1 1 1 1 Lysine methyltransferase MTS PF05175.14 OQR82217.1 - 0.0019 17.8 0.0 0.0027 17.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.6 OQR82217.1 - 0.085 13.6 0.0 0.13 13.0 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Cons_hypoth95 PF03602.15 OQR82217.1 - 0.17 11.5 0.0 0.24 11.0 0.0 1.2 1 0 0 1 1 1 0 Conserved hypothetical protein 95 PRP3 PF08572.10 OQR82218.1 - 4.8e-54 183.4 6.1 4.8e-54 183.4 6.1 2.2 3 0 0 3 3 3 1 pre-mRNA processing factor 3 (PRP3) DUF1115 PF06544.12 OQR82218.1 - 8e-43 146.0 0.3 1.7e-42 145.0 0.3 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1115) BHD_1 PF10403.9 OQR82218.1 - 0.12 12.3 0.0 0.29 11.0 0.0 1.7 1 0 0 1 1 1 0 Rad4 beta-hairpin domain 1 Peptidase_M32 PF02074.15 OQR82218.1 - 0.13 11.0 1.3 0.24 10.1 1.3 1.4 1 0 0 1 1 1 0 Carboxypeptidase Taq (M32) metallopeptidase Pox_P35 PF03213.14 OQR82218.1 - 0.55 9.4 1.7 0.98 8.6 1.7 1.3 1 0 0 1 1 1 0 Poxvirus P35 protein LRR_6 PF13516.6 OQR82219.1 - 0.00022 21.0 2.2 0.81 9.9 0.0 4.6 5 0 0 5 5 5 2 Leucine Rich repeat LRR_4 PF12799.7 OQR82219.1 - 0.076 13.5 12.2 0.49 10.9 0.1 4.4 5 0 0 5 5 5 0 Leucine Rich repeats (2 copies) AAA PF00004.29 OQR82220.1 - 1.9e-60 203.0 0.0 6e-44 149.7 0.0 2.3 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) PEX-1N PF09262.11 OQR82220.1 - 7.5e-22 77.5 2.9 8.3e-22 77.4 0.8 2.1 2 0 0 2 2 2 1 Peroxisome biogenesis factor 1, N-terminal AAA_16 PF13191.6 OQR82220.1 - 1.8e-13 51.2 3.9 3.2e-05 24.4 0.1 3.9 2 2 0 2 2 2 2 AAA ATPase domain RuvB_N PF05496.12 OQR82220.1 - 7.4e-10 38.8 0.0 2.2e-05 24.2 0.0 2.7 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 OQR82220.1 - 1e-09 38.8 1.2 0.039 14.2 0.1 4.6 3 2 0 3 3 2 2 AAA domain AAA_5 PF07728.14 OQR82220.1 - 2.1e-08 34.3 0.1 0.0053 16.8 0.0 3.7 3 2 0 3 3 3 2 AAA domain (dynein-related subfamily) AAA_lid_3 PF17862.1 OQR82220.1 - 4.8e-08 32.7 0.0 0.0012 18.6 0.0 2.5 2 0 0 2 2 2 2 AAA+ lid domain AAA_14 PF13173.6 OQR82220.1 - 2.7e-07 30.7 0.0 0.0058 16.7 0.0 2.4 2 0 0 2 2 2 2 AAA domain NACHT PF05729.12 OQR82220.1 - 5e-07 29.8 0.7 0.098 12.6 0.0 3.7 3 1 0 3 3 2 2 NACHT domain RNA_helicase PF00910.22 OQR82220.1 - 2.8e-06 27.7 0.0 0.035 14.5 0.0 2.6 2 0 0 2 2 2 2 RNA helicase AAA_25 PF13481.6 OQR82220.1 - 2e-05 24.3 4.4 0.26 10.8 0.0 4.3 3 1 1 4 4 4 1 AAA domain AAA_33 PF13671.6 OQR82220.1 - 2e-05 24.8 0.0 0.014 15.5 0.0 2.9 3 0 0 3 3 2 1 AAA domain AAA_18 PF13238.6 OQR82220.1 - 2e-05 25.1 0.0 0.04 14.5 0.0 2.8 2 0 0 2 2 2 1 AAA domain DUF815 PF05673.13 OQR82220.1 - 2.9e-05 23.3 0.0 0.0056 15.9 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF815) IstB_IS21 PF01695.17 OQR82220.1 - 4.3e-05 23.3 0.0 0.071 12.8 0.0 2.4 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_2 PF07724.14 OQR82220.1 - 4.7e-05 23.6 0.0 0.0016 18.6 0.0 2.5 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) ABC_tran PF00005.27 OQR82220.1 - 8.3e-05 23.1 0.0 0.25 11.8 0.0 2.9 3 0 0 3 3 2 1 ABC transporter ATPase_2 PF01637.18 OQR82220.1 - 0.00024 21.1 0.0 0.86 9.5 0.0 2.4 2 0 0 2 2 2 2 ATPase domain predominantly from Archaea Zeta_toxin PF06414.12 OQR82220.1 - 0.00028 20.2 0.1 0.21 10.8 0.0 2.6 3 0 0 3 3 3 1 Zeta toxin Mg_chelatase PF01078.21 OQR82220.1 - 0.00033 20.1 0.2 0.017 14.5 0.1 2.8 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_28 PF13521.6 OQR82220.1 - 0.00037 20.8 0.0 0.049 13.9 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.6 OQR82220.1 - 0.00041 20.1 0.0 0.72 9.6 0.0 2.4 2 0 0 2 2 2 2 AAA domain TsaE PF02367.17 OQR82220.1 - 0.00062 19.8 0.0 0.089 12.8 0.0 2.6 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_29 PF13555.6 OQR82220.1 - 0.00072 19.3 0.0 0.15 11.8 0.0 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_7 PF12775.7 OQR82220.1 - 0.0014 18.1 0.0 2 7.9 0.0 2.3 2 0 0 2 2 2 2 P-loop containing dynein motor region KAP_NTPase PF07693.14 OQR82220.1 - 0.003 16.9 0.0 1.5 8.0 0.0 2.8 2 1 0 3 3 3 1 KAP family P-loop domain RsgA_GTPase PF03193.16 OQR82220.1 - 0.003 17.5 0.0 0.34 10.8 0.0 2.5 2 0 0 2 2 2 1 RsgA GTPase Sigma54_activat PF00158.26 OQR82220.1 - 0.0032 17.2 0.0 1 9.0 0.0 2.8 2 1 0 2 2 2 1 Sigma-54 interaction domain NTPase_1 PF03266.15 OQR82220.1 - 0.0033 17.4 0.1 1.8 8.5 0.0 2.6 2 0 0 2 2 2 1 NTPase AFG1_ATPase PF03969.16 OQR82220.1 - 0.0037 16.2 0.0 0.19 10.6 0.0 2.4 2 0 0 2 2 2 1 AFG1-like ATPase AAA_17 PF13207.6 OQR82220.1 - 0.0087 16.5 0.0 0.27 11.7 0.1 2.6 2 0 0 2 2 2 1 AAA domain TIP49 PF06068.13 OQR82220.1 - 0.0091 15.2 0.0 0.021 14.0 0.0 1.5 2 0 0 2 2 1 1 TIP49 P-loop domain Rad17 PF03215.15 OQR82220.1 - 0.011 15.7 0.0 1.3 8.9 0.0 2.3 2 0 0 2 2 2 0 Rad17 P-loop domain DUF883 PF05957.13 OQR82220.1 - 0.015 15.9 0.9 0.043 14.4 0.9 1.8 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF883) TniB PF05621.11 OQR82220.1 - 0.016 14.6 0.0 5.5 6.4 0.0 2.8 3 0 0 3 3 2 0 Bacterial TniB protein Bac_DnaA PF00308.18 OQR82220.1 - 0.022 14.6 0.0 4.4 7.1 0.0 2.3 2 0 0 2 2 2 0 Bacterial dnaA protein NB-ARC PF00931.22 OQR82220.1 - 0.032 13.4 0.1 1.9 7.6 0.0 2.7 2 1 0 2 2 2 0 NB-ARC domain Viral_helicase1 PF01443.18 OQR82220.1 - 0.037 13.7 1.0 3.9 7.2 0.0 2.9 2 1 1 3 3 3 0 Viral (Superfamily 1) RNA helicase AAA_23 PF13476.6 OQR82220.1 - 0.045 14.3 0.0 8.4 6.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain Caprin-1_dimer PF18293.1 OQR82220.1 - 0.059 13.9 0.0 0.13 12.7 0.0 1.6 1 0 0 1 1 1 0 Caprin-1 dimerization domain AAA_3 PF07726.11 OQR82220.1 - 0.078 12.8 0.0 1.2 9.0 0.0 2.4 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) DAP3 PF10236.9 OQR82220.1 - 0.15 11.2 0.0 8.6 5.4 0.0 2.3 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 WD40 PF00400.32 OQR82221.1 - 2.3e-53 177.0 30.3 4e-07 30.6 0.1 12.9 13 0 0 13 13 13 11 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OQR82221.1 - 8.4e-12 45.2 9.4 0.19 12.1 0.1 9.7 4 3 7 11 11 11 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 OQR82221.1 - 0.0001 21.1 2.5 0.027 13.2 0.1 3.5 3 1 1 4 4 4 2 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 OQR82221.1 - 0.00026 20.1 1.0 4.7 6.1 0.0 4.9 4 1 1 5 5 5 2 WD40 region of Ge1, enhancer of mRNA-decapping protein His_Phos_2 PF00328.22 OQR82222.1 - 7.6e-07 28.8 0.1 0.0001 21.8 0.1 2.4 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Acetyltransf_1 PF00583.25 OQR82223.1 - 2.2e-14 53.7 0.0 2.7e-14 53.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 OQR82223.1 - 7.8e-11 42.3 0.0 1.3e-10 41.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 OQR82223.1 - 3.9e-09 36.5 0.0 5.2e-09 36.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 OQR82223.1 - 3.5e-08 33.3 0.0 4.8e-08 32.9 0.0 1.2 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_3 PF13302.7 OQR82223.1 - 6.8e-07 30.0 0.0 8.7e-07 29.7 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 OQR82223.1 - 0.00021 21.4 0.0 0.00038 20.5 0.0 1.5 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_15 PF17013.5 OQR82223.1 - 0.00074 19.0 0.0 0.00081 18.9 0.0 1.3 1 0 0 1 1 1 1 Putative acetyl-transferase Acetyltransf_4 PF13420.7 OQR82223.1 - 0.039 14.1 0.0 0.048 13.8 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_13 PF13880.6 OQR82223.1 - 0.084 12.9 0.0 0.16 12.0 0.0 1.4 1 0 0 1 1 1 0 ESCO1/2 acetyl-transferase AstA PF04958.12 OQR82223.1 - 0.17 10.4 0.0 0.23 10.0 0.0 1.1 1 0 0 1 1 1 0 Arginine N-succinyltransferase beta subunit DIOX_N PF14226.6 OQR82224.1 - 1.4e-08 35.5 0.0 2.6e-08 34.6 0.0 1.5 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 OQR82224.1 - 0.00077 19.9 0.0 0.0036 17.7 0.0 2.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily TFIIE_alpha PF02002.17 OQR82225.1 - 7.3e-05 22.6 0.4 0.0002 21.2 0.4 1.8 1 0 0 1 1 1 1 TFIIE alpha subunit K_channel_TID PF07941.11 OQR82225.1 - 0.026 15.0 4.9 0.051 14.0 4.9 1.4 1 0 0 1 1 1 0 Potassium channel Kv1.4 tandem inactivation domain DUF1936 PF09151.10 OQR82225.1 - 4.5 7.3 6.5 0.34 10.9 0.8 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1936) Paf1 PF03985.13 OQR82226.1 - 4.9e-49 167.5 2.4 4.9e-49 167.5 2.4 2.5 2 1 0 2 2 2 1 Paf1 SAC3_GANP PF03399.16 OQR82226.1 - 2e-32 112.8 2.5 6.8e-32 111.0 2.5 1.9 1 1 0 1 1 1 1 SAC3/GANP family Glucosamine_iso PF01182.20 OQR82226.1 - 9.2e-16 58.4 0.0 1.7e-15 57.5 0.0 1.4 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase CDC45 PF02724.14 OQR82226.1 - 0.027 12.8 5.0 0.043 12.1 5.0 1.2 1 0 0 1 1 1 0 CDC45-like protein EamA PF00892.20 OQR82227.1 - 4.7e-12 46.2 24.8 1.6e-07 31.6 7.1 2.2 2 0 0 2 2 2 2 EamA-like transporter family AMP-binding PF00501.28 OQR82228.1 - 6.5e-78 262.2 0.0 8.1e-78 261.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme ACAS_N PF16177.5 OQR82228.1 - 9.2e-25 86.3 1.5 2.5e-24 85.0 1.5 1.8 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus AMP-binding_C PF13193.6 OQR82228.1 - 4e-21 75.8 2.0 8.8e-21 74.7 1.1 2.0 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Thioredoxin_8 PF13905.6 OQR82229.1 - 4.3e-24 84.6 0.1 1.9e-23 82.6 0.0 2.1 2 0 0 2 2 2 1 Thioredoxin-like C2 PF00168.30 OQR82229.1 - 3.1e-15 56.3 0.0 4.3e-07 30.2 0.0 2.7 2 0 0 2 2 2 2 C2 domain Thioredoxin PF00085.20 OQR82229.1 - 2.3e-08 33.9 0.0 1.1e-05 25.3 0.0 2.6 1 1 0 1 1 1 1 Thioredoxin C1_1 PF00130.22 OQR82229.1 - 8.5e-07 28.8 4.4 8.5e-07 28.8 4.4 2.5 3 0 0 3 3 3 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Thioredoxin_2 PF13098.6 OQR82229.1 - 1.9e-05 25.1 0.0 5e-05 23.7 0.0 1.7 1 0 0 1 1 1 1 Thioredoxin-like domain AhpC-TSA PF00578.21 OQR82229.1 - 4.4e-05 23.4 0.0 0.00012 21.9 0.0 1.7 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 OQR82229.1 - 0.00011 21.9 0.0 0.00024 20.8 0.0 1.5 1 0 0 1 1 1 1 Redoxin C1_2 PF03107.16 OQR82229.1 - 0.0035 17.6 4.1 0.0038 17.5 1.7 2.4 2 0 0 2 2 2 1 C1 domain Thioredoxin_9 PF14595.6 OQR82229.1 - 0.0047 16.7 0.1 0.073 12.8 0.0 2.6 2 1 1 3 3 3 1 Thioredoxin DUF639 PF04842.12 OQR82229.1 - 0.15 11.5 0.1 0.26 10.7 0.1 1.3 1 0 0 1 1 1 0 Plant protein of unknown function (DUF639) zf-RING_9 PF13901.6 OQR82229.1 - 0.81 9.6 5.6 0.95 9.4 2.7 2.2 2 0 0 2 2 2 0 Putative zinc-RING and/or ribbon PHD PF00628.29 OQR82229.1 - 2.3 8.2 9.5 0.92 9.5 5.7 2.3 2 0 0 2 2 2 0 PHD-finger Na_Ca_ex PF01699.24 OQR82230.1 - 1.4e-30 106.2 46.0 3.3e-16 59.6 10.3 3.3 2 1 1 3 3 3 2 Sodium/calcium exchanger protein Rbx_binding PF18113.1 OQR82230.1 - 0.022 14.5 0.1 0.047 13.5 0.1 1.4 1 0 0 1 1 1 0 Rubredoxin binding C-terminal domain ELP6 PF09807.9 OQR82230.1 - 0.29 10.5 0.9 0.53 9.7 0.9 1.4 1 0 0 1 1 1 0 Elongation complex protein 6 Exo_endo_phos_2 PF14529.6 OQR82231.1 - 0.0013 18.5 1.0 0.0018 18.1 1.0 1.2 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.23 OQR82231.1 - 0.022 14.3 0.5 0.026 14.0 0.5 1.3 1 0 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family Disintegrin PF00200.23 OQR82233.1 - 1.9e-12 47.8 46.2 2.2e-06 28.4 12.0 4.0 3 2 0 3 3 3 3 Disintegrin Helicase_C_2 PF13307.6 OQR82233.1 - 0.45 10.7 1.2 12 6.0 0.1 2.5 3 0 0 3 3 3 0 Helicase C-terminal domain Aa_trans PF01490.18 OQR82245.1 - 2.1e-19 69.6 3.8 2.3e-19 69.4 3.8 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Fimbrial_K88 PF02432.15 OQR82245.1 - 0.07 13.1 0.0 0.1 12.6 0.0 1.3 1 0 0 1 1 1 0 Fimbrial, major and minor subunit YrhC PF14143.6 OQR82245.1 - 4.9 7.3 5.9 32 4.7 0.1 3.7 4 0 0 4 4 4 0 YrhC-like protein DIT1_PvcA PF05141.12 OQR82246.1 - 1.7e-55 188.4 0.3 4e-54 183.9 0.3 2.0 1 1 0 1 1 1 1 Pyoverdine/dityrosine biosynthesis protein Aa_trans PF01490.18 OQR82256.1 - 4.6e-13 48.7 0.8 5.3e-13 48.5 0.8 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Fimbrial_K88 PF02432.15 OQR82256.1 - 0.051 13.6 0.0 0.074 13.0 0.0 1.3 1 0 0 1 1 1 0 Fimbrial, major and minor subunit HA PF03457.14 OQR82272.1 - 4.9e-22 78.0 6.3 2.7e-09 37.2 0.0 4.8 5 1 0 5 5 5 4 Helicase associated domain Pkinase_Tyr PF07714.17 OQR82273.1 - 2.8e-09 36.6 0.0 3.3e-09 36.4 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OQR82273.1 - 3.4e-09 36.4 0.1 3.9e-09 36.2 0.1 1.0 1 0 0 1 1 1 1 Protein kinase domain ABC_membrane PF00664.23 OQR82275.1 - 1.4e-07 31.4 0.1 1.9e-07 31.0 0.1 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region SDF PF00375.18 OQR82278.1 - 1.9e-31 109.5 12.6 2.1e-31 109.3 12.6 1.0 1 0 0 1 1 1 1 Sodium:dicarboxylate symporter family Lipase_GDSL PF00657.22 OQR82279.1 - 2.8e-07 30.7 0.0 2.9e-07 30.7 0.0 1.0 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.6 OQR82279.1 - 9.3e-06 26.2 0.0 9.8e-06 26.1 0.0 1.0 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family ABC_membrane PF00664.23 OQR82282.1 - 1.1e-30 107.2 9.0 1.4e-30 106.9 9.0 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region IstB_IS21 PF01695.17 OQR82290.1 - 0.017 14.8 0.0 0.027 14.2 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_10 PF12846.7 OQR82290.1 - 0.13 11.2 0.0 0.18 10.7 0.0 1.1 1 0 0 1 1 1 0 AAA-like domain ResIII PF04851.15 OQR82290.1 - 0.13 12.2 0.0 0.19 11.7 0.0 1.2 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit ABC2_membrane PF01061.24 OQR82297.1 - 2.3e-13 50.1 5.5 2.3e-13 50.1 5.5 2.0 2 0 0 2 2 2 1 ABC-2 type transporter PDR_assoc PF08370.11 OQR82297.1 - 6.5e-08 32.2 2.4 1.9e-07 30.7 2.4 1.8 1 0 0 1 1 1 1 Plant PDR ABC transporter associated ABC_tran PF00005.27 OQR82297.1 - 1.1e-05 26.0 1.4 1.9e-05 25.2 1.4 1.4 1 0 0 1 1 1 1 ABC transporter RsgA_GTPase PF03193.16 OQR82297.1 - 0.00092 19.2 0.2 0.0018 18.2 0.2 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_29 PF13555.6 OQR82297.1 - 0.0015 18.3 0.8 0.0028 17.3 0.8 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC2_membrane_3 PF12698.7 OQR82297.1 - 0.0031 16.7 8.2 0.005 16.0 8.2 1.2 1 0 0 1 1 1 1 ABC-2 family transporter protein AAA_25 PF13481.6 OQR82297.1 - 0.044 13.4 0.4 0.082 12.5 0.4 1.4 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 OQR82297.1 - 0.1 13.1 1.0 0.17 12.3 1.0 1.3 1 0 0 1 1 1 0 AAA domain DUF3961 PF13106.6 OQR82297.1 - 0.13 11.9 2.5 0.28 10.9 2.5 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3961) HA PF03457.14 OQR82363.1 - 4.4e-40 135.8 7.8 7.2e-10 39.1 0.1 4.1 4 0 0 4 4 4 4 Helicase associated domain Ehbp PF10622.9 OQR82363.1 - 0.0019 18.2 2.8 10 6.2 0.1 3.7 4 0 0 4 4 4 2 Energy-converting hydrogenase B subunit P (EhbP) MutL_C PF08676.11 OQR82363.1 - 0.012 15.4 0.2 27 4.5 0.0 4.0 4 1 0 4 4 4 0 MutL C terminal dimerisation domain Glyco_hydro_130 PF04041.13 OQR82363.1 - 0.096 11.6 0.0 27 3.6 0.0 3.0 1 1 0 3 3 3 0 beta-1,4-mannooligosaccharide phosphorylase KLRAQ PF10205.9 OQR82363.1 - 0.1 12.9 1.5 60 4.0 0.0 3.4 3 0 0 3 3 3 0 Predicted coiled-coil domain-containing protein PagL PF09411.10 OQR82363.1 - 0.2 11.8 1.1 3.1 8.0 0.0 2.8 2 2 1 3 3 3 0 Lipid A 3-O-deacylase (PagL) FliJ PF02050.16 OQR82363.1 - 1.1 9.5 3.4 16 5.8 0.1 2.6 3 0 0 3 3 3 0 Flagellar FliJ protein MULE PF10551.9 OQR82378.1 - 0.039 14.4 0.1 0.071 13.5 0.1 1.4 1 0 0 1 1 1 0 MULE transposase domain gag-asp_proteas PF13975.6 OQR82380.1 - 0.0087 16.6 0.0 0.0099 16.4 0.0 1.2 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 OQR82380.1 - 0.077 13.6 0.0 0.082 13.6 0.0 1.3 1 0 0 1 1 1 0 Aspartyl protease V_ATPase_prox PF18274.1 OQR82380.1 - 0.14 12.2 0.0 0.2 11.7 0.0 1.4 1 0 0 1 1 1 0 Vacuolar ATPase Subunit I N-terminal proximal lobe Pkinase PF00069.25 OQR82394.1 - 1.5e-27 96.6 0.0 1.8e-27 96.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQR82394.1 - 1.7e-25 89.8 0.0 2.1e-25 89.5 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 OQR82394.1 - 0.18 10.7 0.0 0.2 10.6 0.0 1.1 1 0 0 1 1 1 0 Haspin like kinase domain Pkinase PF00069.25 OQR82395.1 - 3.8e-05 23.2 0.0 3.8e-05 23.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQR82395.1 - 0.00082 18.7 0.0 0.00083 18.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Carb_anhydrase PF00194.21 OQR82397.1 - 3.6e-21 75.9 0.1 1.3e-20 74.0 0.1 1.7 1 1 0 1 1 1 1 Eukaryotic-type carbonic anhydrase Ank PF00023.30 OQR82423.1 - 1.7e-17 63.0 0.8 9.2e-10 38.5 0.1 3.3 2 1 1 3 3 3 3 Ankyrin repeat Ank_2 PF12796.7 OQR82423.1 - 6.7e-13 49.0 0.2 1.9e-11 44.4 0.2 2.2 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OQR82423.1 - 4e-11 42.1 0.1 8.7e-06 25.7 0.0 3.3 2 1 1 3 3 3 2 Ankyrin repeat Ank_4 PF13637.6 OQR82423.1 - 1.7e-10 41.2 0.1 5.6e-05 23.6 0.0 2.3 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 OQR82423.1 - 6.2e-08 32.8 0.6 0.0013 19.0 0.0 2.2 1 1 1 2 2 2 2 Ankyrin repeats (many copies) EHN PF06441.12 OQR82423.1 - 0.17 12.2 0.1 0.56 10.6 0.0 1.8 1 1 1 2 2 2 0 Epoxide hydrolase N terminus ABC2_membrane PF01061.24 OQR82424.1 - 1.5e-36 125.8 28.2 1.8e-36 125.5 28.2 1.1 1 0 0 1 1 1 1 ABC-2 type transporter ERGIC_N PF13850.6 OQR82424.1 - 1.4 9.3 4.9 7.9 6.9 0.7 2.5 2 0 0 2 2 2 0 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Redoxin PF08534.10 OQR82436.1 - 3.2e-25 88.6 0.0 3.6e-25 88.4 0.0 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 OQR82436.1 - 4.1e-09 36.4 0.0 4.9e-09 36.2 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family ADH_N PF08240.12 OQR82457.1 - 4.8e-25 87.6 6.7 8.7e-25 86.7 6.7 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 OQR82457.1 - 9.2e-10 38.6 0.1 2.5e-09 37.2 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 OQR82457.1 - 0.00035 20.0 0.0 0.00051 19.5 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 OQR82457.1 - 0.014 14.7 0.0 0.028 13.7 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain ABC_membrane PF00664.23 OQR82459.1 - 1e-33 117.2 1.1 1.2e-33 116.9 1.1 1.0 1 0 0 1 1 1 1 ABC transporter transmembrane region DraK_HK_N PF18092.1 OQR82488.1 - 0.036 14.5 0.0 0.047 14.1 0.0 1.2 1 0 0 1 1 1 0 DraK Histidine Kinase N-terminal domain CNP1 PF08750.11 OQR82499.1 - 0.11 12.5 0.1 0.41 10.6 0.0 1.9 2 0 0 2 2 2 0 CNP1-like family Ammonium_transp PF00909.21 OQR82500.1 - 1.4e-71 241.3 17.3 1.7e-71 241.0 17.3 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family YuiB PF14068.6 OQR82500.1 - 0.043 14.4 2.4 0.078 13.6 0.2 2.5 3 0 0 3 3 3 0 Putative membrane protein BPL_N PF09825.9 OQR82541.1 - 5.8e-06 25.6 0.2 7.2e-06 25.3 0.2 1.1 1 0 0 1 1 1 1 Biotin-protein ligase, N terminal GATase_5 PF13507.6 OQR82541.1 - 0.0054 15.9 0.0 0.0057 15.8 0.0 1.1 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain GATase_3 PF07685.14 OQR82541.1 - 0.0099 15.5 0.0 0.012 15.2 0.0 1.1 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain Ank PF00023.30 OQR82559.1 - 1.8e-61 202.0 11.0 4.4e-08 33.2 0.0 8.1 8 0 0 8 8 8 8 Ankyrin repeat Ank_2 PF12796.7 OQR82559.1 - 6.1e-60 199.8 14.7 4.8e-14 52.7 0.2 5.4 1 1 5 6 6 6 6 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OQR82559.1 - 2.6e-44 144.1 5.2 0.00043 20.5 0.0 8.1 8 0 0 8 8 8 8 Ankyrin repeat Ank_4 PF13637.6 OQR82559.1 - 4.9e-42 141.8 7.1 7.4e-11 42.4 0.1 6.4 3 2 3 6 6 6 6 Ankyrin repeats (many copies) Ank_5 PF13857.6 OQR82559.1 - 7.9e-30 102.5 5.0 0.0003 21.0 0.0 7.8 2 2 6 8 8 8 7 Ankyrin repeats (many copies) MobC PF05713.11 OQR82559.1 - 6.2 7.4 7.5 20 5.8 0.1 3.9 3 0 0 3 3 3 0 Bacterial mobilisation protein (MobC) zf-RING_5 PF14634.6 OQR82573.1 - 0.033 14.2 1.5 0.053 13.5 1.5 1.3 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_7 PF02591.15 OQR82573.1 - 0.12 12.5 0.0 25 5.2 0.1 2.5 2 0 0 2 2 2 0 C4-type zinc ribbon domain Ntox14 PF15522.6 OQR82600.1 - 0.32 10.4 1.6 0.52 9.7 0.2 1.8 1 1 1 2 2 2 0 Novel toxin 14 DUF1356 PF07092.12 OQR82647.1 - 0.028 13.7 0.0 0.029 13.6 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1356) CtaG_Cox11 PF04442.14 OQR82649.1 - 5.7e-62 208.2 0.0 7.7e-62 207.8 0.0 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein CtaG/Cox11 cNMP_binding PF00027.29 OQR82650.1 - 1.3e-07 31.6 0.0 2.3e-07 30.8 0.0 1.4 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain PI3K_rbd PF00794.18 OQR82669.1 - 0.0081 16.3 0.0 0.013 15.6 0.0 1.3 1 0 0 1 1 1 1 PI3-kinase family, ras-binding domain AMA-1 PF02430.15 OQR82669.1 - 0.043 12.8 1.5 0.22 10.4 0.5 1.9 1 1 1 2 2 2 0 Apical membrane antigen 1 DUF3682 PF12446.8 OQR82669.1 - 3.4 8.2 7.2 5.4 7.5 7.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3682) PAC1 PF16094.5 OQR82669.1 - 4.4 6.4 7.1 6.2 5.9 6.5 1.5 1 1 0 1 1 1 0 Proteasome assembly chaperone 4 Ank_2 PF12796.7 OQR82816.1 - 2.3e-27 95.4 0.4 1.1e-16 61.1 0.0 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQR82816.1 - 4.6e-26 90.8 0.1 2.1e-10 40.9 0.0 2.7 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 OQR82816.1 - 2.7e-15 56.0 1.2 8.7e-05 22.8 0.0 3.9 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.6 OQR82816.1 - 4.8e-15 55.4 3.1 3.2e-06 27.3 0.2 3.6 1 1 3 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQR82816.1 - 9.4e-15 53.3 0.0 0.00044 20.5 0.0 3.9 4 0 0 4 4 4 3 Ankyrin repeat Nitro_FeMo-Co PF02579.17 OQR82816.1 - 0.088 13.2 0.2 5.6 7.4 0.1 2.2 1 1 1 2 2 2 0 Dinitrogenase iron-molybdenum cofactor PEGA PF08308.11 OQR82816.1 - 0.14 12.1 0.3 4.4 7.3 0.0 2.7 3 0 0 3 3 3 0 PEGA domain Ricin_B_lectin PF00652.22 OQR82980.1 - 5.9e-06 26.6 0.1 0.00039 20.7 0.2 2.2 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain Mito_carr PF00153.27 OQR82981.1 - 4.4e-25 87.4 3.3 3.6e-22 78.1 0.2 2.0 2 0 0 2 2 2 2 Mitochondrial carrier protein ABC_membrane PF00664.23 OQR83043.1 - 5.1e-26 91.9 6.2 5.5e-26 91.8 6.2 1.0 1 0 0 1 1 1 1 ABC transporter transmembrane region E2F_TDP PF02319.20 OQR83043.1 - 0.011 15.8 0.3 1.2 9.3 0.1 2.1 2 0 0 2 2 2 0 E2F/DP family winged-helix DNA-binding domain Pkinase_Tyr PF07714.17 OQR83044.1 - 2.2e-13 50.1 0.0 2.5e-13 49.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OQR83044.1 - 6.5e-09 35.5 0.0 8.1e-09 35.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Ank_3 PF13606.6 OQR83044.1 - 2.3e-05 24.4 0.0 5.3e-05 23.3 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeat Ank PF00023.30 OQR83044.1 - 0.00049 20.4 0.0 0.0016 18.8 0.0 1.9 2 0 0 2 2 2 1 Ankyrin repeat Ank_2 PF12796.7 OQR83044.1 - 0.00085 19.9 0.1 0.0092 16.6 0.0 2.0 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) ABC1 PF03109.16 OQR83044.1 - 0.067 13.4 0.0 0.095 12.9 0.0 1.3 1 0 0 1 1 1 0 ABC1 family SBDS_C PF09377.10 OQR83075.1 - 2.9e-35 120.8 1.6 4.5e-35 120.2 1.6 1.3 1 0 0 1 1 1 1 SBDS protein C-terminal domain L27_1 PF09058.10 OQR83075.1 - 0.27 11.2 0.9 2.1 8.4 0.1 2.5 3 0 0 3 3 3 0 L27_1 DUF1697 PF08002.11 OQR83078.1 - 5.6e-30 104.6 0.0 7.8e-30 104.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1697) Sugar_tr PF00083.24 OQR83079.1 - 1.7e-13 50.2 0.5 2e-13 50.0 0.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OQR83079.1 - 0.0011 17.9 0.3 0.0012 17.8 0.3 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily ThrE PF06738.12 OQR83079.1 - 0.26 10.6 2.2 0.31 10.4 2.2 1.2 1 0 0 1 1 1 0 Putative threonine/serine exporter DUF2167 PF09935.9 OQR83079.1 - 0.88 8.7 2.4 1.1 8.3 2.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2167) Sugar_tr PF00083.24 OQR83080.1 - 9.2e-12 44.6 2.6 1e-11 44.4 2.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OQR83080.1 - 0.00079 18.4 1.5 0.00089 18.3 1.5 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily ABC2_membrane PF01061.24 OQR83083.1 - 1.5e-32 112.7 28.9 2.4e-32 112.1 28.9 1.3 1 0 0 1 1 1 1 ABC-2 type transporter PDR_assoc PF08370.11 OQR83083.1 - 1.1e-07 31.4 0.5 1.1e-07 31.4 0.5 2.6 2 0 0 2 2 2 1 Plant PDR ABC transporter associated ABC2_membrane_3 PF12698.7 OQR83083.1 - 4.5e-05 22.7 18.2 4.5e-05 22.7 18.2 1.5 1 1 0 1 1 1 1 ABC-2 family transporter protein 5_nucleotid PF05761.14 OQR83084.1 - 6.9e-16 58.2 0.1 9.5e-16 57.7 0.1 1.1 1 0 0 1 1 1 1 5' nucleotidase family IMS PF00817.20 OQR83085.1 - 0.0051 16.8 0.9 0.011 15.7 0.0 2.0 3 0 0 3 3 3 1 impB/mucB/samB family BRCT_2 PF16589.5 OQR83087.1 - 1.6e-08 34.8 0.0 2e-08 34.5 0.0 1.1 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 OQR83087.1 - 6.4e-07 29.7 0.0 8e-07 29.4 0.0 1.2 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 OQR83087.1 - 6.7e-07 29.2 0.1 8.9e-07 28.8 0.1 1.1 1 0 0 1 1 1 1 twin BRCT domain LIG3_BRCT PF16759.5 OQR83087.1 - 0.0015 18.8 0.0 0.002 18.4 0.0 1.2 1 0 0 1 1 1 1 DNA ligase 3 BRCT domain Peptidase_M16 PF00675.20 OQR83087.1 - 0.083 12.9 0.0 0.099 12.6 0.0 1.1 1 0 0 1 1 1 0 Insulinase (Peptidase family M16) CBM_1 PF00734.18 OQR83091.1 - 8.7e-12 44.8 4.4 8.7e-12 44.8 4.4 1.6 2 0 0 2 2 2 1 Fungal cellulose binding domain CCDC24 PF15669.5 OQR83092.1 - 0.021 14.7 0.0 0.033 14.1 0.0 1.3 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 24 family DUF349 PF03993.12 OQR83092.1 - 0.27 11.5 4.5 1.1 9.6 4.5 2.0 1 1 0 1 1 1 0 Domain of Unknown Function (DUF349) TMEM72 PF16054.5 OQR83093.1 - 0.031 14.0 0.7 0.057 13.1 0.1 1.7 1 1 1 2 2 2 0 Transmembrane protein family 72 DUF3098 PF11297.8 OQR83093.1 - 0.036 13.7 1.8 0.092 12.4 1.1 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3098) CAP PF00188.26 OQR83094.1 - 1e-10 42.5 4.9 1e-10 42.5 4.9 1.6 2 0 0 2 2 2 1 Cysteine-rich secretory protein family PT PF04886.12 OQR83094.1 - 0.25 10.9 120.4 0.29 10.7 33.2 4.7 1 1 3 4 4 4 0 PT repeat PT PF04886.12 OQR83095.1 - 9.9e-14 50.6 86.2 7.9e-06 25.3 19.5 4.4 1 1 2 3 3 3 3 PT repeat CBM_1 PF00734.18 OQR83095.1 - 5.2e-11 42.3 12.7 5.2e-11 42.3 12.7 1.8 2 0 0 2 2 2 1 Fungal cellulose binding domain CtIP_N PF10482.9 OQR83098.1 - 0.099 12.7 0.1 0.19 11.8 0.1 1.5 1 0 0 1 1 1 0 Tumour-suppressor protein CtIP N-terminal domain FF PF01846.19 OQR83099.1 - 4.2e-11 42.9 4.4 9.6e-11 41.7 0.5 2.8 2 0 0 2 2 2 1 FF domain WW PF00397.26 OQR83099.1 - 2.3e-08 34.0 6.3 2.3e-05 24.4 3.1 2.6 2 0 0 2 2 2 2 WW domain kleA_kleC PF17383.2 OQR83099.1 - 0.043 14.1 1.0 0.043 14.1 1.0 2.8 3 0 0 3 3 3 0 Uncharacterized KorC regulated protein A Orthopox_A5L PF06193.11 OQR83099.1 - 0.2 11.1 5.2 0.23 10.9 3.0 2.1 2 0 0 2 2 2 0 Orthopoxvirus A5L protein-like Zip PF02535.22 OQR83099.1 - 5.6 6.1 6.4 0.3 10.3 0.2 1.8 2 0 0 2 2 2 0 ZIP Zinc transporter Alpha_kinase PF02816.18 OQR83100.1 - 0.02 15.0 0.0 0.038 14.1 0.0 1.4 1 0 0 1 1 1 0 Alpha-kinase family ABC_membrane PF00664.23 OQR83102.1 - 1.9e-49 168.8 18.4 2.5e-49 168.4 18.4 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 OQR83102.1 - 3.7e-07 30.7 0.0 8.9e-07 29.5 0.0 1.7 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 OQR83102.1 - 0.0013 18.2 0.2 0.0029 17.1 0.2 1.6 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain DNA_mis_repair PF01119.19 OQR83102.1 - 0.12 12.0 0.0 4.1 7.1 0.0 2.4 2 0 0 2 2 2 0 DNA mismatch repair protein, C-terminal domain TMEM213 PF15192.6 OQR83102.1 - 0.18 11.8 0.4 0.37 10.8 0.4 1.5 1 0 0 1 1 1 0 TMEM213 family AAA PF00004.29 OQR83102.1 - 0.38 11.2 2.5 0.86 10.0 0.7 2.3 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) DUF5424 PF17462.2 OQR83107.1 - 0.045 13.7 0.1 0.081 12.9 0.1 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5424) Esterase PF00756.20 OQR83108.1 - 2.9e-15 56.6 0.0 3.3e-15 56.4 0.0 1.0 1 0 0 1 1 1 1 Putative esterase AdoMet_dc PF02675.15 OQR83108.1 - 0.085 13.1 0.0 0.13 12.6 0.0 1.2 1 0 0 1 1 1 0 S-adenosylmethionine decarboxylase ABC_tran PF00005.27 OQR83127.1 - 3.9e-17 63.1 0.0 5.4e-17 62.6 0.0 1.2 1 0 0 1 1 1 1 ABC transporter MMR_HSR1 PF01926.23 OQR83127.1 - 0.0011 19.0 0.0 0.0021 18.1 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_23 PF13476.6 OQR83127.1 - 0.0083 16.7 0.0 0.012 16.1 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 OQR83127.1 - 0.009 15.7 0.0 0.019 14.7 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.6 OQR83127.1 - 0.021 15.2 0.0 0.03 14.7 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain RsgA_GTPase PF03193.16 OQR83127.1 - 0.028 14.3 0.0 0.042 13.8 0.0 1.2 1 0 0 1 1 1 0 RsgA GTPase DUF815 PF05673.13 OQR83127.1 - 0.046 12.9 0.0 0.066 12.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) T2SSE PF00437.20 OQR83127.1 - 0.058 12.4 0.1 0.31 10.1 0.1 1.8 2 0 0 2 2 2 0 Type II/IV secretion system protein DUF87 PF01935.17 OQR83127.1 - 0.086 12.9 0.1 0.13 12.3 0.1 1.2 1 0 0 1 1 1 0 Helicase HerA, central domain IstB_IS21 PF01695.17 OQR83127.1 - 0.094 12.4 0.0 0.15 11.8 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein FtsK_SpoIIIE PF01580.18 OQR83127.1 - 0.096 12.0 0.0 0.14 11.5 0.0 1.2 1 0 0 1 1 1 0 FtsK/SpoIIIE family MeaB PF03308.16 OQR83127.1 - 0.15 11.0 0.1 0.22 10.4 0.1 1.1 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Roc PF08477.13 OQR83127.1 - 0.17 12.1 0.0 0.28 11.4 0.0 1.3 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase TrwB_AAD_bind PF10412.9 OQR83127.1 - 0.22 10.4 0.0 0.31 9.9 0.0 1.1 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain Abhydrolase_1 PF00561.20 OQR83137.1 - 2.5e-06 27.4 0.5 9e-06 25.5 0.0 1.9 2 0 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 OQR83137.1 - 0.0003 20.1 0.1 0.003 16.9 0.1 2.0 1 1 0 1 1 1 1 Serine aminopeptidase, S33 DUF2920 PF11144.8 OQR83137.1 - 0.033 13.3 0.1 0.056 12.6 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2920) Abhydrolase_4 PF08386.10 OQR83137.1 - 0.037 14.2 0.1 0.13 12.4 0.1 1.9 1 1 0 1 1 1 0 TAP-like protein ABC2_membrane PF01061.24 OQR83141.1 - 1.9e-41 141.8 28.1 1.9e-41 141.8 28.1 1.7 2 0 0 2 2 2 1 ABC-2 type transporter PDR_assoc PF08370.11 OQR83141.1 - 3.4e-06 26.7 0.5 3.4e-06 26.7 0.5 2.6 3 0 0 3 3 3 1 Plant PDR ABC transporter associated ABC2_membrane_3 PF12698.7 OQR83141.1 - 0.00046 19.4 28.5 0.00079 18.6 28.5 1.3 1 1 0 1 1 1 1 ABC-2 family transporter protein CNOT1_CAF1_bind PF16415.5 OQR83183.1 - 0.0054 16.2 0.6 0.0061 16.0 0.6 1.0 1 0 0 1 1 1 1 CCR4-NOT transcription complex subunit 1 CAF1-binding domain Cmc1 PF08583.10 OQR83185.1 - 6.2e-12 45.4 2.9 7.2e-12 45.2 2.9 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like Pet191_N PF10203.9 OQR83185.1 - 0.055 13.8 1.0 1.9 8.9 0.3 2.2 2 1 0 2 2 2 0 Cytochrome c oxidase assembly protein PET191 Pkinase PF00069.25 OQR83186.1 - 0.00046 19.6 0.0 0.0005 19.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQR83186.1 - 0.1 11.9 0.0 0.14 11.4 0.0 1.1 1 0 0 1 1 1 0 Protein tyrosine kinase Esterase PF00756.20 OQR83187.1 - 5.3e-38 131.1 0.6 5.8e-38 131.0 0.6 1.0 1 0 0 1 1 1 1 Putative esterase Hydrolase_4 PF12146.8 OQR83187.1 - 0.00014 21.3 0.1 0.0003 20.1 0.1 1.4 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Esterase_phd PF10503.9 OQR83187.1 - 0.0023 17.4 0.1 0.0035 16.9 0.1 1.3 1 1 0 1 1 1 1 Esterase PHB depolymerase Peptidase_S9 PF00326.21 OQR83187.1 - 0.0097 15.4 0.1 0.042 13.3 0.0 1.9 1 1 0 2 2 2 1 Prolyl oligopeptidase family Tannase PF07519.11 OQR83187.1 - 0.036 13.0 0.1 0.036 13.0 0.1 1.2 1 0 0 1 1 1 0 Tannase and feruloyl esterase EcoRII-N PF09217.10 OQR83187.1 - 0.054 13.2 0.0 0.087 12.6 0.0 1.3 1 0 0 1 1 1 0 Restriction endonuclease EcoRII, N-terminal Ank_2 PF12796.7 OQR83196.1 - 9.2e-06 26.2 0.2 0.026 15.1 0.0 2.0 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQR83196.1 - 6e-05 23.5 0.0 0.011 16.3 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQR83196.1 - 0.00014 22.0 0.5 8.6 7.3 0.0 4.0 4 0 0 4 4 4 1 Ankyrin repeat Ank_5 PF13857.6 OQR83196.1 - 0.00063 20.0 0.5 1.4 9.3 0.0 3.4 1 1 3 4 4 4 2 Ankyrin repeats (many copies) CAP PF00188.26 OQR83197.1 - 2.2e-12 47.9 0.1 3.2e-11 44.2 0.1 2.2 1 1 0 1 1 1 1 Cysteine-rich secretory protein family Retrotrans_gag PF03732.17 OQR83200.1 - 4.5e-10 39.7 0.0 8.1e-10 38.9 0.0 1.4 1 0 0 1 1 1 1 Retrotransposon gag protein zf-CCHC PF00098.23 OQR83200.1 - 4.4e-05 23.4 3.5 0.0001 22.2 3.5 1.7 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_4 PF14392.6 OQR83200.1 - 0.00012 21.8 0.3 0.00027 20.6 0.3 1.6 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_5 PF14787.6 OQR83200.1 - 0.078 12.7 2.0 0.16 11.7 2.0 1.4 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger MOZART1 PF12554.8 OQR83200.1 - 0.13 12.1 1.0 0.77 9.6 0.0 2.4 3 0 0 3 3 3 0 Mitotic-spindle organizing gamma-tubulin ring associated E1-E2_ATPase PF00122.20 OQR83205.1 - 9e-46 155.7 0.2 1.3e-45 155.2 0.2 1.2 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_N PF00690.26 OQR83205.1 - 8.1e-13 47.9 0.0 1.7e-12 46.9 0.0 1.5 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus AbiJ_NTD5 PF18865.1 OQR83233.1 - 0.02 14.7 0.0 0.02 14.7 0.0 1.1 1 0 0 1 1 1 0 AbiJ N-terminal domain 5 AbiJ_NTD5 PF18865.1 OQR83234.1 - 0.044 13.6 0.0 0.046 13.5 0.0 1.1 1 0 0 1 1 1 0 AbiJ N-terminal domain 5 MFS_1 PF07690.16 OQR83236.1 - 2.1e-08 33.5 13.5 3.4e-08 32.8 13.5 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily ABC_membrane PF00664.23 OQR83253.1 - 2.9e-13 50.1 2.5 3.4e-13 49.9 2.5 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region DUF1304 PF06993.12 OQR83253.1 - 0.14 12.2 3.9 0.96 9.5 3.9 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF1304) PIH1_CS PF18201.1 OQR83295.1 - 3.7e-07 30.5 0.4 6.8e-07 29.6 0.4 1.4 1 0 0 1 1 1 1 PIH1 CS-like domain DUF2462 PF09495.10 OQR83295.1 - 1.9 9.3 11.5 22 5.8 6.9 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2462) S_100 PF01023.19 OQR83296.1 - 0.015 15.0 0.0 0.031 14.0 0.0 1.6 1 0 0 1 1 1 0 S-100/ICaBP type calcium binding domain PRT_C PF08372.10 OQR83296.1 - 0.16 11.7 0.2 0.31 10.8 0.2 1.4 1 0 0 1 1 1 0 Plant phosphoribosyltransferase C-terminal Pkinase PF00069.25 OQR83297.1 - 7.1e-50 169.8 0.0 9.6e-50 169.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQR83297.1 - 5.7e-18 65.1 0.0 8.3e-18 64.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OQR83297.1 - 0.00066 19.1 0.0 0.04 13.2 0.0 2.1 2 0 0 2 2 2 1 Kinase-like Choline_kinase PF01633.20 OQR83297.1 - 0.0078 15.8 0.1 0.027 14.1 0.0 1.9 2 0 0 2 2 2 1 Choline/ethanolamine kinase Kdo PF06293.14 OQR83297.1 - 0.018 14.4 0.0 0.031 13.6 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OQR83297.1 - 0.19 11.6 0.0 0.42 10.5 0.0 1.5 1 1 0 1 1 1 0 Phosphotransferase enzyme family Metallophos PF00149.28 OQR83298.1 - 4.3e-12 47.0 1.4 8e-12 46.1 1.4 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Pur_ac_phosph_N PF16656.5 OQR83298.1 - 1.5e-08 35.0 3.1 3e-08 34.1 3.1 1.4 1 0 0 1 1 1 1 Purple acid Phosphatase, N-terminal domain Metallophos_2 PF12850.7 OQR83298.1 - 0.011 16.0 0.0 0.016 15.4 0.0 1.3 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain fn3 PF00041.21 OQR83298.1 - 0.066 13.6 0.6 0.13 12.6 0.6 1.5 1 0 0 1 1 1 0 Fibronectin type III domain Lipocalin_4 PF13648.6 OQR83298.1 - 1.2 10.2 6.5 12 6.9 6.4 2.5 1 1 0 1 1 1 0 Lipocalin-like domain Ricin_B_lectin PF00652.22 OQR83318.1 - 2e-05 24.9 0.0 3.3e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain HSF_DNA-bind PF00447.17 OQR83328.1 - 4.8e-24 84.8 0.9 8.7e-24 84.0 0.9 1.4 1 0 0 1 1 1 1 HSF-type DNA-binding DNA_pol_B_exo2 PF10108.9 OQR83328.1 - 0.026 14.2 0.1 0.037 13.7 0.1 1.2 1 0 0 1 1 1 0 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB Proteasom_PSMB PF10508.9 OQR83328.1 - 0.16 10.5 0.0 0.21 10.1 0.0 1.1 1 0 0 1 1 1 0 Proteasome non-ATPase 26S subunit Ribosomal_S7 PF00177.21 OQR83329.1 - 4.5e-36 123.7 1.2 5.7e-36 123.4 1.2 1.1 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e ABC_membrane PF00664.23 OQR83367.1 - 6.8e-32 111.2 13.8 8.6e-32 110.9 13.8 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 OQR83367.1 - 5e-06 27.1 0.0 1e-05 26.0 0.0 1.6 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.23 OQR83372.1 - 3.7e-27 95.7 6.6 4.4e-27 95.4 6.6 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region PDR_CDR PF06422.12 OQR83374.1 - 0.00019 21.2 0.1 0.00034 20.5 0.1 1.4 1 0 0 1 1 1 1 CDR ABC transporter ABC2_membrane PF01061.24 OQR83374.1 - 0.0007 19.1 4.6 0.0007 19.1 4.6 1.9 2 0 0 2 2 2 1 ABC-2 type transporter Peptidase_C23 PF05379.11 OQR83375.1 - 0.13 12.4 0.0 0.15 12.2 0.0 1.1 1 0 0 1 1 1 0 Carlavirus endopeptidase Peptidase_S10 PF00450.22 OQR83387.1 - 7.2e-20 71.8 2.5 7.7e-20 71.7 2.5 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase SMC_N PF02463.19 OQR83388.1 - 0.017 14.5 0.1 0.02 14.3 0.1 1.0 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain ABC_membrane PF00664.23 OQR83389.1 - 4.6e-48 164.2 8.4 6.3e-48 163.8 8.4 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region YwiC PF14256.6 OQR83389.1 - 0.013 15.8 0.2 0.034 14.5 0.2 1.6 1 0 0 1 1 1 0 YwiC-like protein DUF2207 PF09972.9 OQR83389.1 - 5.3 5.7 5.8 2.3 6.9 3.4 1.7 2 1 0 2 2 2 0 Predicted membrane protein (DUF2207) Abhydrolase_1 PF00561.20 OQR83391.1 - 7.9e-07 29.0 0.1 1.4e-06 28.2 0.1 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 OQR83391.1 - 0.00047 19.5 0.0 0.45 9.7 0.0 2.4 2 0 0 2 2 2 2 Serine aminopeptidase, S33 CBM_1 PF00734.18 OQR83399.1 - 2e-34 117.2 68.9 7.6e-10 38.6 7.4 6.8 6 0 0 6 6 6 6 Fungal cellulose binding domain HOCHOB PF17943.1 OQR83399.1 - 3.2 8.5 15.4 11 6.7 0.3 4.3 3 1 1 4 4 4 0 Homeobox-cysteine loop-homeobox Crystall PF00030.19 OQR83399.1 - 9.1 6.6 8.4 17 5.7 0.9 3.4 2 2 1 3 3 3 0 Beta/Gamma crystallin ABC_membrane PF00664.23 OQR83404.1 - 9.5e-28 97.6 14.1 1.3e-27 97.2 14.1 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 OQR83404.1 - 2.7e-07 31.2 0.2 5.7e-07 30.1 0.2 1.6 1 0 0 1 1 1 1 ABC transporter Rhodanese PF00581.20 OQR83404.1 - 0.031 14.8 0.0 0.41 11.2 0.0 2.3 2 0 0 2 2 2 0 Rhodanese-like domain MMR_HSR1 PF01926.23 OQR83404.1 - 0.037 14.1 0.2 0.075 13.1 0.2 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase TatD_DNase PF01026.21 OQR83406.1 - 8.3e-41 140.1 0.0 9.3e-41 139.9 0.0 1.0 1 0 0 1 1 1 1 TatD related DNase PH PF00169.29 OQR83408.1 - 7.7e-10 39.2 0.1 7.6e-06 26.4 0.3 2.4 2 1 0 2 2 2 2 PH domain PH_11 PF15413.6 OQR83408.1 - 0.053 14.0 0.8 0.36 11.3 0.7 2.2 2 1 0 2 2 2 0 Pleckstrin homology domain RGS PF00615.19 OQR83418.1 - 3.1e-10 40.4 0.0 5.6e-10 39.5 0.0 1.4 1 0 0 1 1 1 1 Regulator of G protein signaling domain Herpes_LAMP2 PF06126.11 OQR83418.1 - 0.016 13.8 0.8 0.021 13.5 0.8 1.1 1 0 0 1 1 1 0 Herpesvirus Latent membrane protein 2 Nucleos_tra2_C PF07662.13 OQR83420.1 - 0.022 14.6 1.0 0.025 14.4 1.0 1.1 1 0 0 1 1 1 0 Na+ dependent nucleoside transporter C-terminus DUF1673 PF07895.11 OQR83420.1 - 0.048 13.4 5.1 0.041 13.6 3.2 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1673) EamA PF00892.20 OQR83420.1 - 0.36 11.0 11.4 0.88 9.7 11.4 1.8 1 1 0 1 1 1 0 EamA-like transporter family RseC_MucC PF04246.12 OQR83420.1 - 6.4 6.7 6.3 2 8.4 3.3 1.7 1 1 1 2 2 2 0 Positive regulator of sigma(E), RseC/MucC LAMTOR5 PF16672.5 OQR83421.1 - 2.5e-07 30.5 0.4 3.1e-07 30.2 0.4 1.1 1 0 0 1 1 1 1 Ragulator complex protein LAMTOR5 Myb_DNA-binding PF00249.31 OQR83422.1 - 0.0063 16.7 0.1 0.013 15.6 0.1 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Histone PF00125.24 OQR83426.1 - 4.3e-51 172.7 0.4 4.7e-51 172.6 0.4 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 OQR83426.1 - 0.0018 18.6 0.0 0.0027 18.0 0.0 1.2 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 OQR83426.1 - 0.002 18.3 0.1 0.0039 17.3 0.0 1.6 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold PAF PF15715.5 OQR83426.1 - 0.015 15.9 1.4 0.018 15.6 1.4 1.1 1 0 0 1 1 1 0 PCNA-associated factor histone like domain CBFD_NFYB_HMF PF00808.23 OQR83426.1 - 0.025 14.8 0.0 0.058 13.7 0.0 1.6 2 0 0 2 2 2 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-T_C PF15511.6 OQR83427.1 - 6.4e-09 35.9 0.0 7.7e-09 35.6 0.0 1.1 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 OQR83427.1 - 5.7e-05 23.4 0.1 7e-05 23.1 0.1 1.3 1 1 0 1 1 1 1 CENP-S protein TAF PF02969.17 OQR83427.1 - 0.00027 21.0 0.1 0.00035 20.7 0.1 1.3 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.23 OQR83427.1 - 0.0014 18.8 0.1 0.002 18.4 0.1 1.4 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 OQR83427.1 - 0.0017 18.7 0.0 0.0017 18.7 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-31kDa PF02291.15 OQR83427.1 - 0.0098 16.0 0.0 0.01 15.9 0.0 1.1 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 OQR83427.1 - 0.041 13.9 0.0 0.059 13.4 0.0 1.2 1 0 0 1 1 1 0 Bromodomain associated Mut7-C PF01927.16 OQR83434.1 - 2e-30 105.8 0.8 7.6e-30 103.9 0.6 2.0 2 0 0 2 2 2 1 Mut7-C RNAse domain DNA_pol_A_exo1 PF01612.20 OQR83434.1 - 1.8e-20 73.4 0.0 4.1e-20 72.2 0.0 1.5 1 0 0 1 1 1 1 3'-5' exonuclease tRNA_edit PF04073.15 OQR83434.1 - 4.8e-19 68.7 0.0 1.3e-18 67.2 0.0 1.8 1 0 0 1 1 1 1 Aminoacyl-tRNA editing domain DUF5615 PF18480.1 OQR83434.1 - 0.0021 17.7 0.1 0.0062 16.3 0.1 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF5615) zf-RRN7 PF11781.8 OQR83434.1 - 0.15 11.8 0.1 0.15 11.8 0.1 1.8 2 0 0 2 2 2 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 zf-IS66 PF13005.7 OQR83434.1 - 0.8 10.2 3.2 21 5.6 0.2 2.7 2 0 0 2 2 2 0 zinc-finger binding domain of transposase IS66 ADH_N PF08240.12 OQR83435.1 - 1.6e-24 85.9 5.9 3.1e-24 85.0 5.9 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 OQR83435.1 - 8.4e-21 74.3 0.0 1.4e-20 73.6 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 OQR83435.1 - 7e-12 46.5 0.0 1.1e-11 45.9 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 OQR83435.1 - 1.7e-06 27.5 0.0 3e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 OQR83435.1 - 0.0005 19.5 0.0 0.00084 18.7 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_10 PF13460.6 OQR83435.1 - 0.032 14.1 0.0 0.049 13.5 0.0 1.3 1 0 0 1 1 1 0 NAD(P)H-binding NAD_binding_7 PF13241.6 OQR83435.1 - 0.093 13.2 0.0 0.17 12.3 0.0 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding GFO_IDH_MocA PF01408.22 OQR83435.1 - 0.11 13.3 0.1 0.29 11.9 0.0 1.8 2 0 0 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold DUF678 PF05077.12 OQR83435.1 - 0.15 12.3 2.3 6.3 7.0 0.6 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF678) Aa_trans PF01490.18 OQR83444.1 - 1.4e-40 139.3 29.0 1.6e-40 139.1 29.0 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Peptidase_C1 PF00112.23 OQR83453.1 - 2.9e-28 99.4 0.4 3.2e-28 99.3 0.4 1.0 1 0 0 1 1 1 1 Papain family cysteine protease tRNA-synt_1_2 PF13603.6 OQR83453.1 - 0.15 11.5 0.0 0.21 11.1 0.0 1.2 1 0 0 1 1 1 0 Leucyl-tRNA synthetase, Domain 2 VWA PF00092.28 OQR83458.1 - 6.7e-24 85.1 0.0 1.1e-23 84.4 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.6 OQR83458.1 - 2.5e-15 56.7 0.0 3.6e-15 56.2 0.0 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 OQR83458.1 - 5.2e-11 43.1 0.0 2.3e-10 41.1 0.0 2.0 2 1 1 3 3 3 1 von Willebrand factor type A domain VWA_CoxE PF05762.14 OQR83458.1 - 0.00017 21.1 0.0 0.00026 20.4 0.0 1.3 1 0 0 1 1 1 1 VWA domain containing CoxE-like protein Tfb4 PF03850.14 OQR83458.1 - 0.0012 18.4 0.0 0.0017 17.9 0.0 1.3 1 1 0 1 1 1 1 Transcription factor Tfb4 DUF2201 PF09967.9 OQR83458.1 - 0.026 14.6 0.0 0.055 13.6 0.0 1.5 1 0 0 1 1 1 0 VWA-like domain (DUF2201) CobT_C PF11775.8 OQR83458.1 - 0.044 13.4 0.0 0.069 12.8 0.0 1.3 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT VWA domain Rad60-SLD PF11976.8 OQR83475.1 - 9.6e-12 44.6 0.0 1.5e-11 44.0 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 OQR83475.1 - 9.4e-06 25.3 0.0 1.4e-05 24.8 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin family ANAPC4_WD40 PF12894.7 OQR83501.1 - 2.3e-06 27.8 0.1 3.2e-05 24.1 0.1 2.4 1 1 1 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 OQR83501.1 - 0.0048 17.7 0.3 0.075 13.9 0.1 2.8 3 0 0 3 3 3 1 WD domain, G-beta repeat Glyco_hydro_18 PF00704.28 OQR83502.1 - 2.3e-25 90.0 0.3 1.7e-24 87.2 0.3 1.9 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 Hist_deacetyl PF00850.19 OQR83522.1 - 3.3e-71 240.3 1.1 4.6e-71 239.8 1.1 1.2 1 0 0 1 1 1 1 Histone deacetylase domain Helicase_C PF00271.31 OQR83523.1 - 2.6e-12 47.1 0.0 3.4e-12 46.7 0.0 1.2 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ERCC3_RAD25_C PF16203.5 OQR83523.1 - 0.066 12.4 0.0 0.083 12.1 0.0 1.1 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase ABC_membrane PF00664.23 OQR83563.1 - 9e-28 97.7 12.5 1.3e-27 97.2 12.5 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 OQR83563.1 - 1.8e-11 44.7 0.3 3.6e-11 43.7 0.3 1.5 1 0 0 1 1 1 1 ABC transporter MMR_HSR1 PF01926.23 OQR83563.1 - 0.008 16.2 0.1 0.017 15.2 0.1 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF87 PF01935.17 OQR83563.1 - 0.19 11.8 0.1 0.32 11.0 0.1 1.3 1 0 0 1 1 1 0 Helicase HerA, central domain Aldedh PF00171.22 OQR83569.1 - 4.1e-58 197.0 0.0 4.5e-58 196.9 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family zf-MIZ PF02891.20 OQR83647.1 - 5.9e-16 58.0 4.1 5.9e-16 58.0 4.1 2.2 2 0 0 2 2 2 1 MIZ/SP-RING zinc finger PINIT PF14324.6 OQR83647.1 - 0.00035 20.9 0.0 0.0007 19.9 0.0 1.4 1 0 0 1 1 1 1 PINIT domain zf-Nse PF11789.8 OQR83647.1 - 0.09 12.6 0.4 0.2 11.5 0.4 1.6 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-Sec23_Sec24 PF04810.15 OQR83647.1 - 0.25 11.4 5.7 6.3 6.9 0.1 2.7 2 0 0 2 2 2 0 Sec23/Sec24 zinc finger MRNIP PF15749.5 OQR83647.1 - 3.6 8.4 8.7 2.6 8.8 4.6 2.5 2 1 0 2 2 2 0 MRN-interacting protein zf_CCCH_4 PF18345.1 OQR83651.1 - 3.5e-07 30.0 22.1 2.6e-05 24.1 3.7 3.2 3 0 0 3 3 3 2 Zinc finger domain zf-CCCH PF00642.24 OQR83651.1 - 7.8e-06 25.7 19.8 1.7e-05 24.6 4.2 2.5 3 0 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 OQR83651.1 - 0.0012 18.6 14.2 0.0019 17.9 2.9 2.5 2 0 0 2 2 2 2 CCCH-type zinc finger Torus PF16131.5 OQR83651.1 - 0.0052 17.5 21.7 0.023 15.4 1.6 3.4 2 1 0 3 3 3 2 Torus domain LRV_FeS PF05484.11 OQR83651.1 - 0.02 14.9 1.9 4.8 7.3 0.1 2.3 2 0 0 2 2 2 0 LRV protein FeS4 cluster RHH_6 PF16762.5 OQR83651.1 - 0.02 15.5 0.0 1.4 9.6 0.0 2.7 2 0 0 2 2 2 0 Ribbon-helix-helix domain zf-like PF04071.12 OQR83651.1 - 0.084 12.8 5.1 0.52 10.3 0.8 2.4 2 0 0 2 2 2 0 Cysteine-rich small domain zf-CCCH_2 PF14608.6 OQR83651.1 - 0.099 13.2 9.9 1.3 9.6 1.4 2.7 3 0 0 3 3 3 0 RNA-binding, Nab2-type zinc finger zf-CCCH_3 PF15663.5 OQR83651.1 - 0.18 12.0 9.0 2.2 8.6 1.9 2.8 2 1 0 2 2 2 0 Zinc-finger containing family DUF4789 PF16033.5 OQR83651.1 - 5.9 7.5 8.1 4.8 7.8 3.1 2.7 1 1 2 3 3 3 0 Domain of unknown function (DUF4789) Pkinase_Tyr PF07714.17 OQR83677.1 - 3.3e-17 62.6 0.0 3.6e-17 62.5 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OQR83677.1 - 1.7e-13 50.5 0.0 1.8e-13 50.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain 60KD_IMP PF02096.20 OQR83681.1 - 0.76 9.7 2.8 1.1 9.1 2.8 1.3 1 0 0 1 1 1 0 60Kd inner membrane protein Guanylate_cyc PF00211.20 OQR83682.1 - 2.8e-49 167.2 0.1 4e-49 166.7 0.1 1.2 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain MCM PF00493.23 OQR83682.1 - 0.16 11.0 0.1 0.55 9.3 0.1 1.7 2 0 0 2 2 2 0 MCM P-loop domain DUF5418 PF17439.2 OQR83682.1 - 2.2 8.4 11.7 4.8 7.2 11.7 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5418) Hist_deacetyl PF00850.19 OQR83687.1 - 7.2e-10 38.8 0.0 8e-10 38.7 0.0 1.0 1 0 0 1 1 1 1 Histone deacetylase domain RicinB_lectin_2 PF14200.6 OQR83689.1 - 1.8e-07 31.8 11.2 0.55 11.0 0.1 4.6 1 1 3 5 5 5 4 Ricin-type beta-trefoil lectin domain-like FRG1 PF06229.12 OQR83689.1 - 1e-06 28.6 0.0 2.7 7.7 0.0 4.4 2 2 0 4 4 4 3 FRG1-like domain PUA_3 PF17785.1 OQR83689.1 - 0.001 18.9 0.0 13 5.7 0.0 5.0 5 0 0 5 5 5 1 PUA-like domain TonB_2 PF13103.6 OQR83689.1 - 0.026 14.8 0.0 9 6.6 0.0 2.4 2 0 0 2 2 2 0 TonB C terminal Cadherin_4 PF17803.1 OQR83689.1 - 0.28 11.8 2.0 15 6.3 0.0 3.7 3 1 0 3 3 3 0 Bacterial cadherin-like domain Alpha-amyl_C2 PF07821.12 OQR83689.1 - 0.58 10.4 8.2 90 3.4 0.7 5.4 4 3 0 4 4 4 0 Alpha-amylase C-terminal beta-sheet domain Rubredoxin_2 PF18073.1 OQR83689.1 - 6.5 6.6 17.7 4.5 7.1 0.1 5.3 6 0 0 6 6 6 0 Rubredoxin metal binding domain CDH-cyt PF16010.5 OQR83689.1 - 7.5 6.2 13.9 11 5.7 0.1 4.8 4 2 2 6 6 6 0 Cytochrome domain of cellobiose dehydrogenase FliS_cochap PF16522.5 OQR83697.1 - 0.042 13.8 2.1 2.3 8.1 0.0 3.0 3 0 0 3 3 3 0 Flagellar FLiS export co-chaperone, HP1076 DUF3437 PF11919.8 OQR83697.1 - 0.091 12.7 0.2 0.53 10.2 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3437) UME PF08064.13 OQR83697.1 - 0.15 12.0 1.7 3 7.8 0.1 3.5 3 0 0 3 3 3 0 UME (NUC010) domain Aa_trans PF01490.18 OQR83701.1 - 2.6e-32 112.0 17.2 3.8e-32 111.5 17.2 1.2 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein GFO_IDH_MocA PF01408.22 OQR83703.1 - 2.6e-18 67.0 0.2 4e-18 66.4 0.2 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 OQR83703.1 - 2.7e-07 30.6 0.0 7.9e-07 29.1 0.0 1.8 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain Peptidase_C1 PF00112.23 OQR83705.1 - 6e-30 105.0 0.0 6.7e-30 104.8 0.0 1.0 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.15 OQR83705.1 - 0.033 13.0 0.0 0.041 12.7 0.0 1.1 1 0 0 1 1 1 0 Peptidase C1-like family DUF4223 PF13978.6 OQR83705.1 - 0.056 13.4 0.3 0.14 12.1 0.3 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF4223) Glyco_hydro_28 PF00295.17 OQR83707.1 - 1.2e-10 40.9 0.4 1.4e-10 40.8 0.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Glyco_hydro_28 PF00295.17 OQR83708.1 - 5.6e-24 84.8 1.2 1.4e-23 83.5 1.2 1.6 1 1 0 1 1 1 1 Glycosyl hydrolases family 28 HA PF03457.14 OQR83711.1 - 5.3e-14 52.3 2.5 1.7e-05 25.0 0.1 3.1 2 1 0 2 2 2 2 Helicase associated domain DUF4419 PF14388.6 OQR83714.1 - 9.7e-25 87.6 0.3 1.1e-24 87.4 0.3 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4419) Zip PF02535.22 OQR83722.1 - 1.2e-65 222.0 17.1 5.4e-45 154.1 8.1 2.0 1 1 1 2 2 2 2 ZIP Zinc transporter Ost4 PF10215.9 OQR83722.1 - 0.048 13.5 1.7 0.13 12.1 1.7 1.8 1 0 0 1 1 1 0 Oligosaccaryltransferase B12D PF06522.11 OQR83773.1 - 6.2e-12 45.1 0.0 8.5e-12 44.7 0.0 1.2 1 0 0 1 1 1 1 NADH-ubiquinone reductase complex 1 MLRQ subunit Ammonium_transp PF00909.21 OQR83812.1 - 2e-51 174.9 6.3 2.3e-51 174.8 6.3 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family Sdh5 PF03937.16 OQR83814.1 - 5e-21 74.5 0.1 9e-21 73.6 0.1 1.4 1 0 0 1 1 1 1 Flavinator of succinate dehydrogenase Phage_int_SAM_5 PF13102.6 OQR83814.1 - 0.031 14.6 0.0 0.049 14.0 0.0 1.4 1 0 0 1 1 1 0 Phage integrase SAM-like domain Adipokin_hormo PF06377.11 OQR83841.1 - 0.081 13.3 0.0 0.2 12.1 0.0 1.7 1 1 0 1 1 1 0 Adipokinetic hormone Glyco_hydro_1 PF00232.18 OQR83842.1 - 2.2e-60 204.4 0.0 2.4e-60 204.3 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 FMN_red PF03358.15 OQR83842.1 - 0.11 12.2 0.0 0.15 11.8 0.0 1.2 1 0 0 1 1 1 0 NADPH-dependent FMN reductase gag-asp_proteas PF13975.6 OQR83846.1 - 0.00012 22.6 0.0 0.00033 21.2 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 OQR83846.1 - 0.00012 22.6 0.0 0.00045 20.8 0.0 1.9 2 0 0 2 2 2 1 Aspartyl protease DUF3338 PF11819.8 OQR83846.1 - 0.036 14.0 1.5 0.12 12.4 1.5 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF3338) eIF3g PF12353.8 OQR83846.1 - 1.5 9.2 7.1 0.15 12.5 0.9 2.2 1 1 1 2 2 2 0 Eukaryotic translation initiation factor 3 subunit G Oxidored_FMN PF00724.20 OQR83872.1 - 1.7e-27 96.6 0.2 1.9e-27 96.4 0.2 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family DUF1848 PF08902.11 OQR83872.1 - 0.037 13.7 0.0 0.042 13.6 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1848) TMP-TENI PF02581.17 OQR83872.1 - 0.054 12.8 0.0 0.072 12.4 0.0 1.3 1 0 0 1 1 1 0 Thiamine monophosphate synthase PMT2_N PF17987.1 OQR83872.1 - 0.099 12.8 0.1 0.16 12.2 0.1 1.3 1 0 0 1 1 1 0 Phosphoethanolamine N-methyltransferase 2 N-terminal ABC_membrane PF00664.23 OQR83920.1 - 3.2e-16 59.8 0.0 3.4e-16 59.7 0.0 1.0 1 0 0 1 1 1 1 ABC transporter transmembrane region TMEM213 PF15192.6 OQR83920.1 - 0.015 15.2 1.5 0.023 14.7 1.5 1.3 1 0 0 1 1 1 0 TMEM213 family Cellulase PF00150.18 OQR83927.1 - 2.4e-08 33.8 0.0 3.1e-08 33.4 0.0 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) MFS_1 PF07690.16 OQR83930.1 - 0.00033 19.7 2.3 0.00036 19.6 2.3 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF4014 PF13198.6 OQR83930.1 - 0.1 13.0 0.0 0.28 11.6 0.0 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF4014) TLD PF07534.16 OQR83948.1 - 1.8e-17 63.9 0.0 2.3e-17 63.5 0.0 1.1 1 0 0 1 1 1 1 TLD HHH_3 PF12836.7 OQR83949.1 - 0.00047 20.3 0.1 0.00055 20.1 0.1 1.1 1 0 0 1 1 1 1 Helix-hairpin-helix motif IBR PF01485.21 OQR83957.1 - 0.0089 16.2 3.4 0.0089 16.2 3.4 4.3 2 1 1 3 3 3 2 IBR domain, a half RING-finger domain BNIP2 PF12496.8 OQR83958.1 - 0.06 13.8 0.4 0.14 12.6 0.4 1.5 1 0 0 1 1 1 0 Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2 SlyX PF04102.12 OQR83958.1 - 0.12 13.0 3.6 0.83 10.3 1.1 2.6 2 0 0 2 2 2 0 SlyX rRNA_proc-arch PF13234.6 OQR83958.1 - 0.14 12.0 4.5 3.4 7.5 0.0 2.5 2 1 1 3 3 3 0 rRNA-processing arch domain DUF3573 PF12097.8 OQR83958.1 - 0.19 10.5 2.4 0.27 10.0 2.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) Choline_kinase PF01633.20 OQR83976.1 - 1.9e-19 70.1 0.0 2.7e-19 69.6 0.0 1.1 1 0 0 1 1 1 1 Choline/ethanolamine kinase Choline_kinase PF01633.20 OQR83977.1 - 2.2e-31 109.1 0.0 3e-31 108.7 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase PH PF00169.29 OQR83983.1 - 0.0088 16.5 0.0 0.097 13.2 0.0 2.1 2 0 0 2 2 2 1 PH domain IQ_SEC7_PH PF16453.5 OQR83983.1 - 0.1 12.6 0.0 0.2 11.7 0.0 1.6 1 0 0 1 1 1 0 PH domain MatE PF01554.18 OQR83989.1 - 3.2e-37 127.7 30.2 2.8e-19 69.3 12.0 2.4 2 0 0 2 2 2 2 MatE LSM PF01423.22 OQR83990.1 - 8.2e-12 44.6 0.0 2.3e-11 43.2 0.0 1.7 1 0 0 1 1 1 1 LSM domain Tyrosinase PF00264.20 OQR83990.1 - 8.9e-10 39.2 0.3 1.3e-08 35.4 0.3 2.6 1 1 0 1 1 1 1 Common central domain of tyrosinase ABC2_membrane_3 PF12698.7 OQR83993.1 - 7.8e-31 107.4 21.6 9.8e-31 107.1 21.6 1.1 1 0 0 1 1 1 1 ABC-2 family transporter protein DUF4131 PF13567.6 OQR83993.1 - 0.78 9.4 3.4 1.1 8.9 0.8 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) Peptidase_U4 PF03419.13 OQR83993.1 - 5.4 6.2 12.5 0.23 10.7 5.2 2.1 1 1 1 2 2 2 0 Sporulation factor SpoIIGA Ank_2 PF12796.7 OQR83996.1 - 2.4e-29 101.7 21.2 4.1e-08 33.7 0.1 5.4 1 1 6 7 7 7 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQR83996.1 - 6.1e-29 100.0 5.5 2.8e-05 24.5 0.0 7.7 6 2 2 8 8 8 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQR83996.1 - 8.8e-18 62.6 6.7 1.5 9.7 0.0 10.1 9 1 1 10 10 10 4 Ankyrin repeat Ank_5 PF13857.6 OQR83996.1 - 1.5e-15 57.0 10.7 0.0058 16.9 0.0 7.9 6 3 4 10 10 10 6 Ankyrin repeats (many copies) DUF3447 PF11929.8 OQR83996.1 - 3e-11 43.1 11.2 0.00091 19.1 0.1 5.2 4 1 1 5 5 5 3 Domain of unknown function (DUF3447) Ank PF00023.30 OQR83996.1 - 0.0006 20.1 4.5 6.6 7.4 0.0 6.5 5 2 0 5 5 5 1 Ankyrin repeat AAA_16 PF13191.6 OQR83998.1 - 0.051 13.9 0.0 0.091 13.1 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_33 PF13671.6 OQR83998.1 - 0.083 13.1 0.0 0.15 12.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain Ank PF00023.30 OQR84001.1 - 9.4e-28 95.4 7.4 8.3e-08 32.3 0.2 4.0 3 1 1 4 4 4 4 Ankyrin repeat Ank_2 PF12796.7 OQR84001.1 - 5e-25 87.9 2.6 7.3e-13 48.9 0.2 2.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQR84001.1 - 2.6e-23 82.0 2.8 5.8e-11 42.7 0.0 2.7 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQR84001.1 - 6.2e-19 66.1 0.3 0.00019 21.6 0.1 4.1 4 0 0 4 4 4 4 Ankyrin repeat Ank_5 PF13857.6 OQR84001.1 - 1.1e-12 47.9 1.9 4.9e-05 23.5 0.0 3.2 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Imm_superinfect PF14373.6 OQR84001.1 - 0.0025 17.7 0.4 0.85 9.6 0.2 3.1 3 0 0 3 3 3 1 Superinfection immunity protein Arg_repressor PF01316.21 OQR84001.1 - 0.005 16.6 0.5 7.1 6.5 0.0 3.6 4 0 0 4 4 4 1 Arginine repressor, DNA binding domain FokI_N PF02981.15 OQR84001.1 - 0.04 14.1 0.0 1.4 9.1 0.0 2.0 1 1 1 2 2 2 0 Restriction endonuclease FokI, recognition domain UPF0014 PF03649.13 OQR84001.1 - 0.12 11.7 0.1 12 5.1 0.0 2.4 2 1 1 3 3 3 0 Uncharacterised protein family (UPF0014) A_deaminase PF00962.22 OQR84002.1 - 2.2e-87 293.4 0.0 2.6e-87 293.2 0.0 1.0 1 0 0 1 1 1 1 Adenosine/AMP deaminase Myb_DNA-binding PF00249.31 OQR84003.1 - 1.8e-41 140.1 13.4 7.3e-16 58.1 0.1 3.2 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OQR84003.1 - 2.6e-33 114.0 4.6 3.3e-13 49.7 0.0 3.1 1 1 2 3 3 3 3 Myb-like DNA-binding domain SLIDE PF09111.10 OQR84003.1 - 8e-07 29.1 0.0 0.063 13.3 0.0 3.1 1 1 2 3 3 3 2 SLIDE MADF_DNA_bdg PF10545.9 OQR84003.1 - 0.00014 22.1 2.2 0.024 14.9 0.3 3.1 3 0 0 3 3 3 1 Alcohol dehydrogenase transcription factor Myb/SANT-like Rap1_C PF11626.8 OQR84003.1 - 0.00025 21.1 8.2 0.059 13.5 2.5 2.8 2 1 0 2 2 2 2 TRF2-interacting telomeric protein/Rap1 - C terminal domain Myb_DNA-bind_4 PF13837.6 OQR84003.1 - 0.0078 16.6 7.9 0.4 11.1 0.6 3.4 2 1 1 3 3 3 2 Myb/SANT-like DNA-binding domain SANT_DAMP1_like PF16282.5 OQR84003.1 - 0.012 15.8 1.0 0.027 14.7 0.1 2.1 2 2 0 2 2 2 0 SANT/Myb-like domain of DAMP1 Myb_DNA-bind_7 PF15963.5 OQR84003.1 - 0.058 13.3 0.1 0.59 10.1 0.0 2.4 2 1 1 3 3 3 0 Myb DNA-binding like MOZART1 PF12554.8 OQR84005.1 - 1.9e-21 75.6 0.0 2.2e-21 75.3 0.0 1.1 1 0 0 1 1 1 1 Mitotic-spindle organizing gamma-tubulin ring associated Abhydrolase_1 PF00561.20 OQR84006.1 - 2.3e-14 53.7 0.0 3.6e-14 53.0 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 OQR84006.1 - 1.4e-11 44.1 0.0 6.4e-11 42.0 0.0 2.0 2 1 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 OQR84006.1 - 1.1e-06 29.4 0.0 2.3e-06 28.4 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Ank_5 PF13857.6 OQR84008.1 - 1e-11 44.8 0.8 0.014 15.7 0.0 4.5 2 2 3 5 5 5 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 OQR84008.1 - 1.7e-11 44.6 0.5 9.2e-06 26.2 0.0 2.8 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQR84008.1 - 2e-11 44.1 0.1 0.0033 18.0 0.0 4.1 4 0 0 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQR84008.1 - 1.5e-09 37.3 0.1 0.042 14.4 0.0 4.8 5 1 1 6 6 6 3 Ankyrin repeat DUF5049 PF16468.5 OQR84008.1 - 0.021 14.7 0.1 2.8 7.9 0.0 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF5049) Ank PF00023.30 OQR84008.1 - 0.097 13.2 0.0 33 5.2 0.0 3.1 3 0 0 3 3 3 0 Ankyrin repeat SapB_1 PF05184.15 OQR84008.1 - 3.6 7.7 5.3 1.7 8.7 0.5 3.0 4 0 0 4 4 4 0 Saposin-like type B, region 1 Pkinase_Tyr PF07714.17 OQR84009.1 - 7.8e-46 156.5 0.0 1.1e-45 155.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OQR84009.1 - 6.1e-45 153.6 0.0 8.8e-45 153.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Protocadherin PF08374.11 OQR84009.1 - 0.00015 21.8 0.8 0.00024 21.1 0.8 1.3 1 0 0 1 1 1 1 Protocadherin SKG6 PF08693.10 OQR84009.1 - 0.00068 19.0 4.3 0.0019 17.6 4.3 1.7 1 0 0 1 1 1 1 Transmembrane alpha-helix domain APH PF01636.23 OQR84009.1 - 0.0009 19.2 0.0 0.0014 18.6 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family STE2 PF02116.15 OQR84009.1 - 0.0016 17.8 0.3 0.0029 17.0 0.3 1.3 1 0 0 1 1 1 1 Fungal pheromone mating factor STE2 GPCR Adeno_E3_CR2 PF02439.15 OQR84009.1 - 0.0017 18.1 1.3 0.0046 16.7 1.3 1.7 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 Pkinase_fungal PF17667.1 OQR84009.1 - 0.0026 16.6 0.0 0.0038 16.0 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase CD34_antigen PF06365.12 OQR84009.1 - 0.014 15.0 0.0 0.024 14.2 0.0 1.3 1 0 0 1 1 1 0 CD34/Podocalyxin family EphA2_TM PF14575.6 OQR84009.1 - 0.017 16.0 0.0 0.042 14.7 0.0 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain TMEM51 PF15345.6 OQR84009.1 - 0.021 14.6 0.0 0.034 14.0 0.0 1.2 1 0 0 1 1 1 0 Transmembrane protein 51 TMEM154 PF15102.6 OQR84009.1 - 0.022 14.7 0.6 0.041 13.8 0.6 1.4 1 0 0 1 1 1 0 TMEM154 protein family Amnionless PF14828.6 OQR84009.1 - 0.048 12.5 0.0 0.088 11.6 0.0 1.3 1 0 0 1 1 1 0 Amnionless RicinB_lectin_2 PF14200.6 OQR84009.1 - 0.055 14.2 2.9 0.18 12.6 0.3 2.8 1 1 1 2 2 2 0 Ricin-type beta-trefoil lectin domain-like Haspin_kinase PF12330.8 OQR84009.1 - 0.13 11.2 0.0 0.21 10.5 0.0 1.5 1 1 0 1 1 1 0 Haspin like kinase domain Syndecan PF01034.20 OQR84009.1 - 0.14 12.1 0.4 0.29 11.1 0.4 1.5 1 0 0 1 1 1 0 Syndecan domain DUF4834 PF16118.5 OQR84009.1 - 0.15 13.0 0.0 0.34 11.9 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) Mid2 PF04478.12 OQR84009.1 - 1.5 8.7 5.2 3.1 7.6 5.2 1.6 1 1 0 1 1 1 0 Mid2 like cell wall stress sensor AMP-binding PF00501.28 OQR84016.1 - 8.4e-05 21.3 0.0 0.00011 21.0 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme RhoGEF PF00621.20 OQR84023.1 - 4.4e-14 53.1 0.1 8.2e-14 52.2 0.1 1.4 1 0 0 1 1 1 1 RhoGEF domain PH PF00169.29 OQR84023.1 - 7e-05 23.3 0.0 0.00015 22.2 0.0 1.6 1 0 0 1 1 1 1 PH domain PH_10 PF15411.6 OQR84023.1 - 0.071 13.4 0.2 0.3 11.3 0.0 2.0 2 0 0 2 2 2 0 Pleckstrin homology domain PH PF00169.29 OQR84024.1 - 2e-06 28.2 0.0 4.3e-06 27.2 0.0 1.5 1 1 1 2 2 2 1 PH domain EMP70 PF02990.16 OQR84027.1 - 9.8e-160 532.6 6.6 1.4e-159 532.1 6.6 1.2 1 0 0 1 1 1 1 Endomembrane protein 70 zf-C4pol PF14260.6 OQR84035.1 - 0.00056 20.3 7.3 0.00097 19.6 7.3 1.4 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta DZR PF12773.7 OQR84035.1 - 0.0013 18.7 5.3 0.0021 18.1 5.3 1.4 1 0 0 1 1 1 1 Double zinc ribbon Vps36-NZF-N PF16988.5 OQR84035.1 - 0.0034 16.7 5.3 0.45 9.9 1.1 2.3 2 0 0 2 2 2 2 Vacuolar protein sorting 36 NZF-N zinc-finger domain zf-tcix PF14952.6 OQR84035.1 - 0.05 13.2 0.0 0.05 13.2 0.0 1.9 2 0 0 2 2 2 0 Putative treble-clef, zinc-finger, Zn-binding RNA_POL_M_15KD PF02150.16 OQR84035.1 - 0.073 13.0 2.7 8.3 6.4 0.0 3.5 3 1 1 4 4 4 0 RNA polymerases M/15 Kd subunit DUF2116 PF09889.9 OQR84035.1 - 0.7 9.9 7.1 0.2 11.7 0.6 2.3 2 0 0 2 2 2 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) zinc_ribbon_2 PF13240.6 OQR84035.1 - 1.8 8.4 4.8 15 5.5 0.3 2.4 2 0 0 2 2 2 0 zinc-ribbon domain Tnp_zf-ribbon_2 PF13842.6 OQR84035.1 - 5.5 7.9 7.2 8.8 7.2 1.2 2.6 2 1 0 2 2 2 0 DDE_Tnp_1-like zinc-ribbon CEBP_ZZ PF16366.5 OQR84035.1 - 5.7 7.2 8.1 0.77 10.0 0.6 2.5 2 1 0 2 2 2 0 Cytoplasmic polyadenylation element-binding protein ZZ domain Hist_deacetyl PF00850.19 OQR84036.1 - 1.1e-57 195.9 0.5 1.2e-57 195.7 0.5 1.0 1 0 0 1 1 1 1 Histone deacetylase domain PEP-utilisers_N PF05524.13 OQR84037.1 - 0.12 12.6 2.3 0.19 11.9 0.2 2.1 2 0 0 2 2 2 0 PEP-utilising enzyme, N-terminal Fez1 PF06818.15 OQR84037.1 - 0.17 12.3 22.5 0.44 11.0 6.6 2.2 1 1 1 2 2 2 0 Fez1 Rootletin PF15035.6 OQR84037.1 - 0.22 11.5 23.3 0.77 9.8 7.2 3.1 1 1 2 3 3 3 0 Ciliary rootlet component, centrosome cohesion HALZ PF02183.18 OQR84037.1 - 1 9.6 9.6 2.4 8.5 0.1 3.3 3 0 0 3 3 3 0 Homeobox associated leucine zipper YscO PF07321.12 OQR84037.1 - 1.5 8.8 23.2 0.45 10.5 7.7 2.3 1 1 1 2 2 2 0 Type III secretion protein YscO DUF1635 PF07795.11 OQR84037.1 - 7.8 6.3 14.0 0.38 10.6 7.5 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1635) Ammonium_transp PF00909.21 OQR84038.1 - 9.4e-66 222.1 26.7 1.2e-65 221.8 26.7 1.1 1 0 0 1 1 1 1 Ammonium Transporter Family HA PF03457.14 OQR84044.1 - 1.7e-12 47.5 5.5 4.1e-09 36.6 0.0 3.4 4 0 0 4 4 4 3 Helicase associated domain WLM PF08325.10 OQR84045.1 - 3.6e-38 131.6 0.6 1.3e-37 129.7 0.0 2.2 2 0 0 2 2 2 1 WLM domain ABC_tran PF00005.27 OQR84045.1 - 1.5e-34 119.4 11.2 3.2e-18 66.6 0.0 4.9 5 2 0 5 5 3 2 ABC transporter AAA_21 PF13304.6 OQR84045.1 - 5.4e-14 52.7 13.1 6.3e-06 26.2 4.6 4.3 3 1 0 3 3 3 3 AAA domain, putative AbiEii toxin, Type IV TA system PUB PF09409.10 OQR84045.1 - 3.6e-13 49.3 0.0 3.8e-12 46.0 0.0 2.6 2 0 0 2 2 2 1 PUB domain SMC_N PF02463.19 OQR84045.1 - 4.1e-10 39.5 1.2 0.00011 21.7 0.0 4.3 3 2 1 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 OQR84045.1 - 6.5e-08 32.2 0.2 0.008 15.9 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.6 OQR84045.1 - 2.6e-07 31.4 8.3 0.00016 22.3 0.0 4.2 5 0 0 5 5 4 2 AAA domain AAA_30 PF13604.6 OQR84045.1 - 4.1e-07 29.9 3.5 0.00011 22.0 0.0 3.3 3 1 0 4 4 4 1 AAA domain AAA_22 PF13401.6 OQR84045.1 - 5.3e-07 30.0 5.9 0.0046 17.2 0.1 4.2 4 1 0 4 4 3 2 AAA domain AAA_28 PF13521.6 OQR84045.1 - 6.8e-06 26.4 0.0 0.0088 16.3 0.0 3.0 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 OQR84045.1 - 1.7e-05 24.8 0.1 0.038 13.9 0.0 2.9 2 0 0 2 2 2 2 RsgA GTPase AAA_18 PF13238.6 OQR84045.1 - 2e-05 25.1 2.0 0.046 14.3 0.0 3.3 3 0 0 3 3 3 2 AAA domain MMR_HSR1 PF01926.23 OQR84045.1 - 0.00028 20.9 0.4 0.74 9.9 0.0 3.5 3 0 0 3 3 3 1 50S ribosome-binding GTPase ABC_tran_Xtn PF12848.7 OQR84045.1 - 0.00099 19.1 0.6 0.00099 19.1 0.6 3.2 3 0 0 3 3 3 1 ABC transporter DUF815 PF05673.13 OQR84045.1 - 0.001 18.3 1.1 0.48 9.6 0.0 2.9 3 0 0 3 3 3 1 Protein of unknown function (DUF815) AAA_16 PF13191.6 OQR84045.1 - 0.0014 19.0 8.5 0.015 15.7 0.0 3.8 4 1 0 4 4 3 1 AAA ATPase domain AAA_7 PF12775.7 OQR84045.1 - 0.002 17.6 0.1 2.8 7.4 0.0 2.7 2 0 0 2 2 2 2 P-loop containing dynein motor region MeaB PF03308.16 OQR84045.1 - 0.0026 16.8 1.6 0.59 9.1 0.0 2.7 3 0 0 3 3 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB RNA_helicase PF00910.22 OQR84045.1 - 0.0036 17.7 0.0 5 7.6 0.0 2.8 2 0 0 2 2 2 0 RNA helicase IstB_IS21 PF01695.17 OQR84045.1 - 0.0036 17.1 0.0 2.9 7.6 0.0 2.9 3 0 0 3 3 2 1 IstB-like ATP binding protein AAA_5 PF07728.14 OQR84045.1 - 0.0041 17.1 5.8 0.66 10.0 0.1 3.9 4 0 0 4 4 3 1 AAA domain (dynein-related subfamily) NACHT PF05729.12 OQR84045.1 - 0.0044 17.0 0.1 1.2 9.0 0.0 2.6 2 0 0 2 2 2 1 NACHT domain SLT_beta PF02258.16 OQR84045.1 - 0.0046 17.0 0.3 0.013 15.5 0.3 1.7 1 0 0 1 1 1 1 Shiga-like toxin beta subunit SbcCD_C PF13558.6 OQR84045.1 - 0.0047 17.1 0.0 0.4 10.9 0.0 3.5 3 2 0 3 3 3 1 Putative exonuclease SbcCD, C subunit AAA_27 PF13514.6 OQR84045.1 - 0.007 16.0 0.0 0.24 11.0 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 OQR84045.1 - 0.017 15.3 0.7 6.7 6.9 0.0 3.2 3 0 0 3 3 2 0 AAA domain DUF45 PF01863.17 OQR84045.1 - 0.02 14.9 1.2 0.074 13.1 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function DUF45 AAA PF00004.29 OQR84045.1 - 0.025 15.0 0.3 19 5.6 0.0 3.5 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) Roc PF08477.13 OQR84045.1 - 0.03 14.5 0.1 14 5.9 0.0 2.7 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Zeta_toxin PF06414.12 OQR84045.1 - 0.033 13.5 0.1 0.79 9.0 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin Spermine_synt_N PF17284.2 OQR84045.1 - 0.054 13.4 0.0 0.13 12.1 0.0 1.6 1 0 0 1 1 1 0 Spermidine synthase tetramerisation domain Thymidylate_kin PF02223.17 OQR84045.1 - 0.059 13.0 0.5 0.53 9.9 0.0 2.5 2 0 0 2 2 2 0 Thymidylate kinase AAA_25 PF13481.6 OQR84045.1 - 0.066 12.8 0.1 18 4.8 0.0 3.4 3 0 0 3 3 3 0 AAA domain AAA_24 PF13479.6 OQR84045.1 - 0.073 12.8 0.0 11 5.7 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_15 PF13175.6 OQR84045.1 - 0.27 10.9 0.0 0.27 10.9 0.0 3.6 5 0 0 5 5 5 0 AAA ATPase domain ABC_ATPase PF09818.9 OQR84045.1 - 1.6 7.5 6.7 0.14 11.0 0.6 2.3 3 0 0 3 3 3 0 Predicted ATPase of the ABC class DUF724 PF05266.14 OQR84045.1 - 8.3 6.2 7.7 0.67 9.8 0.1 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF724) Far-17a_AIG1 PF04750.14 OQR84046.1 - 0.017 14.5 24.1 0.036 13.4 23.9 1.7 1 1 0 1 1 1 0 FAR-17a/AIG1-like protein p450 PF00067.22 OQR84053.1 - 0.025 13.3 0.0 0.044 12.5 0.0 1.3 1 0 0 1 1 1 0 Cytochrome P450 ABC2_membrane PF01061.24 OQR84082.1 - 2.6e-30 105.4 25.6 2.6e-30 105.4 25.6 1.3 2 0 0 2 2 2 1 ABC-2 type transporter PDR_CDR PF06422.12 OQR84082.1 - 0.00027 20.8 0.2 0.00027 20.8 0.2 2.4 2 0 0 2 2 2 1 CDR ABC transporter PDR_assoc PF08370.11 OQR84082.1 - 0.0063 16.2 6.1 0.033 13.9 0.1 4.2 4 0 0 4 4 4 1 Plant PDR ABC transporter associated Pkinase_Tyr PF07714.17 OQR84093.1 - 1.5e-19 70.3 0.0 2.6e-09 36.8 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 OQR84093.1 - 8.8e-17 61.3 0.0 8.7e-10 38.4 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain DAP10 PF07213.11 OQR84093.1 - 0.017 15.1 0.1 0.032 14.2 0.1 1.4 1 0 0 1 1 1 0 DAP10 membrane protein Syndecan PF01034.20 OQR84093.1 - 0.05 13.5 0.1 0.099 12.6 0.1 1.4 1 0 0 1 1 1 0 Syndecan domain RicinB_lectin_2 PF14200.6 OQR84113.1 - 0.0003 21.5 1.8 0.014 16.1 2.2 2.9 1 1 2 3 3 3 3 Ricin-type beta-trefoil lectin domain-like Pox_LP_H2 PF03356.15 OQR84113.1 - 0.0034 17.3 0.3 0.02 14.8 0.1 2.1 2 0 0 2 2 2 1 Viral late protein H2 Ank_5 PF13857.6 OQR84115.1 - 6.6e-48 160.2 10.4 1.4e-11 44.4 0.1 5.3 2 1 4 6 6 6 6 Ankyrin repeats (many copies) Ank_2 PF12796.7 OQR84115.1 - 4.5e-47 158.6 5.6 1.5e-15 57.5 0.6 4.0 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.30 OQR84115.1 - 1.6e-43 145.3 21.3 2.1e-08 34.2 0.2 7.1 7 0 0 7 7 7 7 Ankyrin repeat Ank_4 PF13637.6 OQR84115.1 - 6.2e-40 135.1 9.7 2e-09 37.8 0.0 6.9 1 1 6 7 7 7 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQR84115.1 - 3.9e-36 119.0 4.1 8.1e-06 25.8 0.0 7.2 7 0 0 7 7 7 7 Ankyrin repeat Packaging_FI PF14000.6 OQR84115.1 - 0.036 14.5 0.3 0.089 13.3 0.1 1.7 2 0 0 2 2 2 0 DNA packaging protein FI A_deamin PF02137.18 OQR84117.1 - 6.7e-53 180.3 4.5 1.6e-52 179.0 4.5 1.5 1 1 0 1 1 1 1 Adenosine-deaminase (editase) domain APOBEC_C PF05240.14 OQR84117.1 - 0.13 12.3 0.0 0.25 11.3 0.0 1.5 1 0 0 1 1 1 0 APOBEC-like C-terminal domain APOBEC2 PF18772.1 OQR84117.1 - 0.13 12.3 0.6 2.2 8.3 0.1 2.2 2 0 0 2 2 2 0 APOBEC2 NCA2 PF08637.10 OQR84130.1 - 9.4e-22 77.5 0.5 2.4e-21 76.2 0.5 1.7 1 0 0 1 1 1 1 ATP synthase regulation protein NCA2 RE_SacI PF09566.10 OQR84131.1 - 0.071 12.9 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 SacI restriction endonuclease zf-C3HC4_2 PF13923.6 OQR84150.1 - 4e-09 36.2 11.4 6.7e-09 35.5 11.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 OQR84150.1 - 1.9e-08 34.0 11.8 3.4e-08 33.2 11.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.6 OQR84150.1 - 5.7e-07 29.3 2.5 9.5e-07 28.6 2.5 1.4 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-RING_5 PF14634.6 OQR84150.1 - 1.1e-06 28.5 12.3 2e-06 27.6 12.3 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 OQR84150.1 - 8.6e-06 25.7 6.5 1.3e-05 25.1 3.5 2.3 1 1 1 2 2 2 1 RING-type zinc-finger zf-RING_2 PF13639.6 OQR84150.1 - 1.1e-05 25.7 11.6 1.8e-05 25.0 11.6 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 OQR84150.1 - 1.5e-05 24.7 9.0 2.8e-05 23.9 9.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 OQR84150.1 - 0.00087 19.4 7.6 0.0015 18.7 7.6 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-ANAPC11 PF12861.7 OQR84150.1 - 0.00094 19.2 3.8 0.0017 18.4 3.8 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.6 OQR84150.1 - 0.0015 18.3 7.6 0.0028 17.5 7.6 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-Nse PF11789.8 OQR84150.1 - 0.0039 17.0 6.4 0.0064 16.3 6.4 1.3 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit Mob_synth_C PF06463.13 OQR84150.1 - 0.0083 16.1 2.0 0.012 15.5 2.0 1.3 1 0 0 1 1 1 1 Molybdenum Cofactor Synthesis C zf-rbx1 PF12678.7 OQR84150.1 - 0.05 13.9 10.7 0.1 12.9 10.7 1.6 1 1 0 1 1 1 0 RING-H2 zinc finger domain zf-C2H2_4 PF13894.6 OQR84150.1 - 0.083 13.8 0.1 0.083 13.8 0.1 3.1 3 0 0 3 3 2 0 C2H2-type zinc finger zf-C3HC4_5 PF17121.5 OQR84150.1 - 0.21 11.5 5.6 0.58 10.1 5.6 1.8 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) DUF2318 PF10080.9 OQR84150.1 - 0.22 11.7 4.4 0.54 10.4 4.2 1.7 1 1 0 1 1 1 0 Predicted membrane protein (DUF2318) zf-RING_10 PF16685.5 OQR84150.1 - 0.23 11.6 4.6 0.41 10.8 4.6 1.4 1 0 0 1 1 1 0 zinc RING finger of MSL2 Trm112p PF03966.16 OQR84150.1 - 0.25 11.9 1.6 0.66 10.6 1.6 1.8 1 1 0 1 1 1 0 Trm112p-like protein zf-RING_4 PF14570.6 OQR84150.1 - 0.3 10.9 5.5 0.73 9.7 5.5 1.7 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-Sec23_Sec24 PF04810.15 OQR84150.1 - 0.4 10.8 4.7 0.74 9.9 2.0 2.4 2 1 0 2 2 2 0 Sec23/Sec24 zinc finger CEBP_ZZ PF16366.5 OQR84150.1 - 0.46 10.8 5.5 1.2 9.5 5.6 1.7 1 1 0 1 1 1 0 Cytoplasmic polyadenylation element-binding protein ZZ domain GAGA PF09237.11 OQR84150.1 - 0.81 9.5 5.8 1.8 8.4 1.4 2.6 1 1 1 2 2 2 0 GAGA factor zf-RING_11 PF17123.5 OQR84150.1 - 1.3 8.8 10.9 35 4.3 0.0 2.4 2 0 0 2 2 2 0 RING-like zinc finger zf-NADH-PPase PF09297.11 OQR84150.1 - 9.9 5.9 10.9 1.1 8.9 5.6 2.2 2 1 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain DUF2723 PF11028.8 OQR84157.1 - 8.9e-25 87.6 7.1 8.9e-25 87.6 7.1 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF2723) PMT_2 PF13231.6 OQR84157.1 - 0.0022 18.3 16.1 0.0036 17.5 16.1 1.4 1 1 0 1 1 1 1 Dolichyl-phosphate-mannose-protein mannosyltransferase BaxI_1 PF12811.7 OQR84157.1 - 0.069 12.7 6.0 0.037 13.6 3.6 1.8 1 1 0 1 1 1 0 Bax inhibitor 1 like AMP-binding_C PF13193.6 OQR84170.1 - 0.0009 20.2 0.0 0.0025 18.8 0.0 1.7 1 1 1 2 2 2 1 AMP-binding enzyme C-terminal domain Borrelia_P83 PF05262.11 OQR84175.1 - 0.059 11.9 8.2 0.081 11.4 8.2 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein OmpH PF03938.14 OQR84175.1 - 0.14 12.5 25.9 0.45 10.8 21.9 2.2 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) UBN_AB PF14075.6 OQR84175.1 - 0.21 11.3 9.6 0.46 10.2 9.6 1.5 1 0 0 1 1 1 0 Ubinuclein conserved middle domain DUF3584 PF12128.8 OQR84175.1 - 0.55 7.7 16.1 0.82 7.1 16.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) V_ATPase_I PF01496.19 OQR84175.1 - 1.2 7.0 5.3 1.7 6.4 5.3 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family AAA_23 PF13476.6 OQR84175.1 - 1.9 9.0 9.8 5.7 7.4 9.8 1.9 1 0 0 1 1 1 0 AAA domain TSP_NTD PF17804.1 OQR84175.1 - 2 8.6 9.6 3.9 7.7 9.6 1.4 1 0 0 1 1 1 0 Tail specific protease N-terminal domain Metal_resist PF13801.6 OQR84175.1 - 5.9 7.1 14.0 17 5.6 13.6 1.9 1 1 1 2 2 2 0 Heavy-metal resistance SprA-related PF12118.8 OQR84175.1 - 6.5 5.8 14.7 10 5.2 14.7 1.2 1 0 0 1 1 1 0 SprA-related family p450 PF00067.22 OQR84193.1 - 3.4e-71 240.4 0.0 3.8e-71 240.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Peptidase_M20 PF01546.28 OQR84195.1 - 3.8e-12 46.3 0.3 5.1e-12 45.9 0.3 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Tub PF01167.18 OQR84209.1 - 9e-21 74.7 0.2 1.7e-20 73.8 0.2 1.5 1 1 0 1 1 1 1 Tub family Ricin_B_lectin PF00652.22 OQR84210.1 - 6.8e-26 91.0 15.9 3e-13 50.1 1.6 2.3 2 0 0 2 2 2 2 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.6 OQR84210.1 - 5e-10 40.0 12.6 0.026 15.2 0.3 4.2 2 2 2 4 4 4 4 Ricin-type beta-trefoil lectin domain-like CDtoxinA PF03498.14 OQR84210.1 - 0.00026 20.6 10.3 0.0026 17.3 2.2 2.7 1 1 1 2 2 2 2 Cytolethal distending toxin A/C domain Aldo_ket_red PF00248.21 OQR84226.1 - 2.7e-44 151.6 0.0 9.3e-28 97.3 0.1 3.0 1 1 1 2 2 2 2 Aldo/keto reductase family Ank_5 PF13857.6 OQR84238.1 - 4.4e-06 26.9 0.1 5.3e-05 23.4 0.1 2.6 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQR84238.1 - 4.4e-06 26.6 0.4 0.0057 17.1 0.1 3.9 3 0 0 3 3 3 1 Ankyrin repeat Ank PF00023.30 OQR84238.1 - 2.4e-05 24.6 0.4 0.00026 21.3 0.5 2.6 2 0 0 2 2 2 1 Ankyrin repeat Ank_4 PF13637.6 OQR84238.1 - 3.1e-05 24.5 0.1 0.0004 20.9 0.0 2.6 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 OQR84238.1 - 0.00086 19.8 0.0 0.0022 18.6 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) DUF3884 PF13024.6 OQR84238.1 - 0.059 12.9 0.5 0.19 11.3 0.5 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3884) Pox_Ag35 PF03286.14 OQR84238.1 - 0.22 11.3 12.7 2.2 8.0 2.0 2.5 2 0 0 2 2 2 0 Pox virus Ag35 surface protein ABC_membrane PF00664.23 OQR84265.1 - 1.6e-26 93.6 14.8 2.2e-26 93.1 14.8 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region TMEM189_B_dmain PF10520.9 OQR84265.1 - 0.057 13.5 0.5 0.42 10.7 0.2 2.3 2 0 0 2 2 2 0 B domain of TMEM189, localisation domain HA PF03457.14 OQR84266.1 - 0.028 14.7 0.0 0.047 14.0 0.0 1.5 1 0 0 1 1 1 0 Helicase associated domain Ank_2 PF12796.7 OQR84269.1 - 1.6e-70 233.7 32.5 2.1e-13 50.7 1.4 6.1 1 1 5 7 7 7 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQR84269.1 - 8.6e-62 204.8 14.0 9.3e-10 38.9 0.0 9.7 4 2 6 10 10 10 10 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQR84269.1 - 1.3e-48 157.3 15.5 0.00081 19.7 0.0 13.1 13 0 0 13 13 13 12 Ankyrin repeat Ank_5 PF13857.6 OQR84269.1 - 6.4e-46 153.8 18.7 3.6e-08 33.5 0.1 9.8 3 2 6 10 10 10 10 Ankyrin repeats (many copies) Ank PF00023.30 OQR84269.1 - 6e-43 143.5 20.3 0.0027 18.1 0.0 12.5 12 1 1 13 13 13 11 Ankyrin repeat HTH_29 PF13551.6 OQR84321.1 - 0.067 13.2 0.0 0.12 12.4 0.0 1.4 1 0 0 1 1 1 0 Winged helix-turn helix Arm PF00514.23 OQR84324.1 - 0.061 13.4 1.2 0.13 12.4 0.5 1.9 2 0 0 2 2 2 0 Armadillo/beta-catenin-like repeat DUF1772 PF08592.11 OQR84325.1 - 1.2e-18 67.7 2.8 1.5e-18 67.5 2.8 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1772) DUF4660 PF15559.6 OQR84326.1 - 0.012 15.9 0.7 0.012 15.9 0.7 2.1 2 2 1 3 3 3 0 Domain of unknown function (DUF4660) DUF4203 PF13886.6 OQR84330.1 - 0.3 10.7 35.3 0.62 9.7 34.8 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4203) DDE_3 PF13358.6 OQR84332.1 - 4.1e-11 42.8 0.0 2.1e-10 40.5 0.0 2.1 1 1 0 1 1 1 1 DDE superfamily endonuclease HTH_32 PF13565.6 OQR84332.1 - 0.062 13.9 0.0 0.21 12.3 0.0 2.0 1 1 0 1 1 1 0 Homeodomain-like domain Glyoxalase_5 PF14696.6 OQR84334.1 - 1.9e-05 24.9 0.3 0.00033 20.8 0.0 2.7 3 0 0 3 3 3 1 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal Glyoxalase_4 PF13669.6 OQR84334.1 - 0.075 13.3 0.0 4.3 7.7 0.0 2.4 2 1 0 2 2 2 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily ORC6 PF05460.13 OQR84334.1 - 0.18 11.1 2.6 0.22 10.7 2.6 1.2 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Glyoxalase_5 PF14696.6 OQR84335.1 - 6e-07 29.7 0.4 2.6e-05 24.4 0.1 2.7 3 0 0 3 3 3 1 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal Glyoxalase_4 PF13669.6 OQR84335.1 - 0.01 16.1 0.1 0.23 11.8 0.0 2.2 2 0 0 2 2 2 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily SIS_2 PF13580.6 OQR84338.1 - 0.035 14.1 0.0 0.054 13.5 0.0 1.3 1 0 0 1 1 1 0 SIS domain NTPase_1 PF03266.15 OQR84338.1 - 0.14 12.0 0.1 0.31 10.9 0.1 1.6 1 1 0 1 1 1 0 NTPase UPF0203 PF05254.12 OQR84341.1 - 0.061 13.6 0.0 0.32 11.3 0.0 1.8 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0203) Hist_deacetyl PF00850.19 OQR84343.1 - 4.5e-16 59.2 0.1 7.4e-16 58.5 0.1 1.3 1 0 0 1 1 1 1 Histone deacetylase domain Ank_4 PF13637.6 OQR84344.1 - 1.1e-42 143.8 0.0 7.7e-12 45.5 0.0 5.0 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank_2 PF12796.7 OQR84344.1 - 3.4e-42 142.9 0.0 1.8e-17 63.7 0.0 3.2 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.30 OQR84344.1 - 1.2e-36 123.5 0.0 8.9e-07 29.1 0.0 6.0 6 0 0 6 6 6 5 Ankyrin repeat Ank_3 PF13606.6 OQR84344.1 - 1.1e-32 108.3 0.0 0.00016 21.9 0.0 6.1 6 0 0 6 6 6 6 Ankyrin repeat Ank_5 PF13857.6 OQR84344.1 - 1.8e-30 104.6 0.0 1.6e-08 34.7 0.0 4.3 2 2 3 5 5 5 5 Ankyrin repeats (many copies) PEGA PF08308.11 OQR84344.1 - 4.8e-07 29.6 0.0 0.41 10.6 0.0 4.2 4 0 0 4 4 4 2 PEGA domain EPSP_synthase PF00275.20 OQR84344.1 - 0.0003 19.6 0.2 1.3 7.6 0.0 3.1 1 1 1 3 3 3 2 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) Nitro_FeMo-Co PF02579.17 OQR84344.1 - 0.0036 17.6 0.0 1.8 9.0 0.0 3.1 1 1 2 3 3 3 1 Dinitrogenase iron-molybdenum cofactor HTH_Tnp_Tc3_1 PF11427.8 OQR84347.1 - 9.5e-05 22.2 0.0 0.00022 21.0 0.0 1.6 1 0 0 1 1 1 1 Tc3 transposase HTH_38 PF13936.6 OQR84347.1 - 0.0017 18.1 0.1 0.0045 16.7 0.0 1.8 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_7 PF02796.15 OQR84347.1 - 0.0085 16.2 0.2 0.26 11.4 0.0 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain of resolvase UPF0122 PF04297.14 OQR84347.1 - 0.04 14.1 0.1 0.059 13.6 0.1 1.5 1 1 0 1 1 1 0 Putative helix-turn-helix protein, YlxM / p13 like HTH_23 PF13384.6 OQR84347.1 - 0.074 12.9 0.0 0.18 11.7 0.0 1.7 2 0 0 2 2 2 0 Homeodomain-like domain Cyclin_N PF00134.23 OQR84350.1 - 4.7e-14 52.2 0.2 7.5e-14 51.6 0.2 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain ABC_tran PF00005.27 OQR84369.1 - 4.8e-09 36.8 0.0 6.3e-09 36.5 0.0 1.2 1 0 0 1 1 1 1 ABC transporter MMR_HSR1 PF01926.23 OQR84369.1 - 0.015 15.3 0.0 0.029 14.5 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_22 PF13401.6 OQR84369.1 - 0.022 15.0 0.0 0.035 14.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 OQR84369.1 - 0.079 12.2 0.0 0.16 11.3 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin ABC2_membrane PF01061.24 OQR84370.1 - 2e-31 109.1 28.1 2e-31 109.1 28.1 1.4 2 0 0 2 2 2 1 ABC-2 type transporter PDR_CDR PF06422.12 OQR84370.1 - 0.00045 20.1 0.1 0.00045 20.1 0.1 2.6 3 1 0 3 3 3 1 CDR ABC transporter DDE_Tnp_4 PF13359.6 OQR84372.1 - 5.4e-32 110.7 0.0 6.1e-32 110.5 0.0 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_1 PF01609.21 OQR84372.1 - 4e-08 33.2 0.0 6e-08 32.6 0.0 1.2 1 0 0 1 1 1 1 Transposase DDE domain Plant_tran PF04827.14 OQR84372.1 - 1.1e-06 28.4 0.5 8.7e-06 25.5 0.5 1.9 1 1 0 1 1 1 1 Plant transposon protein Choline_transpo PF04515.12 OQR84373.1 - 8.7e-13 48.2 0.8 9.7e-13 48.0 0.8 1.1 1 0 0 1 1 1 1 Plasma-membrane choline transporter PRORP PF16953.5 OQR84375.1 - 1.1e-12 48.0 2.1 1.4e-09 37.9 0.1 2.7 2 1 0 2 2 2 2 Protein-only RNase P PPR_long PF17177.4 OQR84375.1 - 8.4e-10 38.4 0.0 1.8e-09 37.3 0.0 1.5 1 0 0 1 1 1 1 Pentacotripeptide-repeat region of PRORP PPR_2 PF13041.6 OQR84375.1 - 0.00047 20.3 0.0 0.57 10.4 0.0 3.0 3 0 0 3 3 3 2 PPR repeat family PPR PF01535.20 OQR84375.1 - 0.0042 17.2 0.0 0.22 11.9 0.0 2.7 2 0 0 2 2 2 1 PPR repeat PI3_PI4_kinase PF00454.27 OQR84376.1 - 8.9e-50 169.8 0.0 1.7e-49 168.9 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FRB_dom PF08771.11 OQR84376.1 - 1.7e-45 153.5 0.1 3.3e-45 152.5 0.1 1.5 1 0 0 1 1 1 1 FKBP12-rapamycin binding domain FAT PF02259.23 OQR84376.1 - 1.1e-19 70.9 0.0 1.5e-19 70.4 0.0 1.2 1 0 0 1 1 1 1 FAT domain GSP_synth PF03738.14 OQR84377.1 - 2.6e-35 122.3 0.0 3.5e-35 121.9 0.0 1.1 1 0 0 1 1 1 1 Glutathionylspermidine synthase preATP-grasp YscJ_FliF PF01514.17 OQR84377.1 - 0.14 11.8 0.1 1.2 8.8 0.0 2.0 2 0 0 2 2 2 0 Secretory protein of YscJ/FliF family Acyl_transf_3 PF01757.22 OQR84409.1 - 2e-21 76.4 31.5 2e-21 76.4 31.5 1.9 1 1 0 1 1 1 1 Acyltransferase family MASE4 PF17158.4 OQR84409.1 - 0.0014 18.0 0.1 0.0014 18.0 0.1 2.3 2 1 0 2 2 2 1 Membrane-associated sensor, integral membrane domain DUF3325 PF11804.8 OQR84409.1 - 0.63 10.2 0.0 0.63 10.2 0.0 4.1 4 0 0 4 4 4 0 Protein of unknown function (DUF3325) Gp_dh_N PF00044.24 OQR84420.1 - 2.3e-24 85.7 0.1 2.5e-24 85.6 0.1 1.0 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DapB_N PF01113.20 OQR84420.1 - 0.0081 16.3 0.0 0.0081 16.3 0.0 1.1 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus 2-Hacid_dh_C PF02826.19 OQR84420.1 - 0.071 12.5 0.0 0.072 12.4 0.0 1.1 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ThiS PF02597.20 OQR84436.1 - 9.6e-13 48.6 0.0 1.1e-12 48.3 0.0 1.1 1 0 0 1 1 1 1 ThiS family ABC_membrane PF00664.23 OQR84461.1 - 3.1e-19 69.7 14.4 4.6e-19 69.1 14.4 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region IQ PF00612.27 OQR84464.1 - 0.00081 19.0 6.8 0.012 15.4 0.5 2.9 2 0 0 2 2 2 2 IQ calmodulin-binding motif C_tripleX PF02363.19 OQR84464.1 - 3.4 8.1 11.3 0.18 12.1 5.5 2.0 2 0 0 2 2 2 0 Cysteine rich repeat COMM_domain PF07258.14 OQR84465.1 - 3.6e-09 36.6 0.2 1.5e-08 34.7 0.0 1.9 2 0 0 2 2 2 1 COMM domain FBA_3 PF08268.12 OQR84465.1 - 0.12 12.4 0.1 0.17 11.8 0.1 1.2 1 0 0 1 1 1 0 F-box associated domain Colicin_E5 PF12106.8 OQR84465.1 - 0.15 12.4 0.3 1.7 9.0 0.1 2.1 1 1 1 2 2 2 0 Colicin E5 ribonuclease domain Methyltransf_28 PF02636.17 OQR84466.1 - 5.5e-37 127.8 0.0 1.3e-36 126.6 0.0 1.5 1 1 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase RrnaAD PF00398.20 OQR84466.1 - 5.3e-05 22.4 0.0 0.0001 21.5 0.0 1.6 1 1 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_12 PF08242.12 OQR84466.1 - 0.00028 21.6 0.0 0.00077 20.2 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 OQR84466.1 - 0.00095 19.8 0.0 0.0057 17.3 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain NodS PF05401.11 OQR84466.1 - 0.087 12.4 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 Nodulation protein S (NodS) Methyltransf_23 PF13489.6 OQR84466.1 - 0.12 12.2 0.0 0.19 11.5 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain NDK PF00334.19 OQR84516.1 - 7.5e-09 35.7 0.0 4.3e-06 26.8 0.0 2.4 2 0 0 2 2 2 2 Nucleoside diphosphate kinase BacA PF02673.18 OQR84516.1 - 0.028 14.2 1.1 0.046 13.4 1.1 1.3 1 0 0 1 1 1 0 Bacitracin resistance protein BacA CBM_1 PF00734.18 OQR84560.1 - 1.8e-22 78.9 65.3 7.6e-11 41.8 8.2 6.0 6 0 0 6 6 6 5 Fungal cellulose binding domain FSAP_sig_propep PF03032.15 OQR84560.1 - 1.4 9.0 4.1 12 6.1 0.0 2.9 3 0 0 3 3 3 0 Frog skin active peptide family signal and propeptide Stealth_CR1 PF17101.5 OQR84579.1 - 3.2e-12 45.9 0.0 5.6e-12 45.2 0.0 1.4 1 0 0 1 1 1 1 Stealth protein CR1, conserved region 1 Stealth_CR2 PF11380.8 OQR84579.1 - 1.1e-06 28.8 0.3 0.00049 20.2 0.1 2.4 2 0 0 2 2 2 2 Stealth protein CR2, conserved region 2 Stealth_CR3 PF17102.5 OQR84580.1 - 1.7e-18 66.3 1.4 4.1e-18 65.0 1.4 1.7 1 0 0 1 1 1 1 Stealth protein CR3, conserved region 3 Notch PF00066.17 OQR84580.1 - 3e-14 53.2 24.7 6.6e-07 29.7 8.8 2.6 2 0 0 2 2 2 2 LNR domain Stealth_CR4 PF17103.5 OQR84580.1 - 7e-10 38.6 0.0 1.5e-09 37.6 0.0 1.5 1 0 0 1 1 1 1 Stealth protein CR4, conserved region 4 Stealth_CR2 PF11380.8 OQR84580.1 - 2.5e-05 24.4 0.2 0.00019 21.6 0.0 2.4 2 0 0 2 2 2 1 Stealth protein CR2, conserved region 2 APC1_C PF18122.1 OQR84580.1 - 0.094 12.7 0.1 3.7 7.5 0.0 2.5 2 1 0 2 2 2 0 Anaphase-promoting complex sub unit 1 C-terminal domain TES PF08034.11 OQR84586.1 - 0.065 13.5 0.2 0.14 12.4 0.2 1.6 1 0 0 1 1 1 0 Trematode eggshell synthesis protein CAF1 PF04857.20 OQR84601.1 - 1e-22 80.8 4.7 1.6e-13 50.5 0.0 2.8 2 1 0 2 2 2 2 CAF1 family ribonuclease LRR_6 PF13516.6 OQR84608.1 - 1.3e-19 68.5 20.7 0.0036 17.3 0.0 8.8 8 0 0 8 8 8 5 Leucine Rich repeat EF-hand_7 PF13499.6 OQR84608.1 - 7.2e-11 42.4 0.0 1.9e-10 41.1 0.0 1.8 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 OQR84608.1 - 1.1e-10 40.2 0.2 0.00032 20.0 0.1 2.8 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 OQR84608.1 - 9e-08 31.5 0.2 0.0017 18.1 0.0 3.1 2 0 0 2 2 2 2 EF-hand domain LRR_1 PF00560.33 OQR84608.1 - 2.5e-07 30.3 3.7 4.9 8.1 0.2 7.5 7 0 0 7 7 7 1 Leucine Rich Repeat EF-hand_8 PF13833.6 OQR84608.1 - 3.1e-06 26.9 0.1 0.0099 15.7 0.0 2.7 1 1 1 2 2 2 2 EF-hand domain pair LRR_4 PF12799.7 OQR84608.1 - 0.00032 21.0 18.4 0.23 11.9 0.3 6.2 3 2 2 5 5 5 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 OQR84608.1 - 0.0016 18.1 15.6 0.017 14.9 0.5 6.0 5 2 0 5 5 5 1 Leucine rich repeat EF-hand_5 PF13202.6 OQR84608.1 - 0.0074 15.7 0.0 0.022 14.3 0.0 1.8 1 0 0 1 1 1 1 EF hand DUF1293 PF06950.11 OQR84608.1 - 0.067 13.3 0.0 0.2 11.8 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1293) Ricin_B_lectin PF00652.22 OQR84609.1 - 2.3e-17 63.4 6.5 2.3e-09 37.6 0.6 3.2 2 1 1 3 3 3 3 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.6 OQR84609.1 - 5.1e-07 30.3 3.0 0.0027 18.4 0.1 3.2 2 1 0 2 2 2 2 Ricin-type beta-trefoil lectin domain-like CDtoxinA PF03498.14 OQR84609.1 - 0.0018 17.9 0.6 0.27 10.8 0.0 2.5 2 1 0 2 2 2 2 Cytolethal distending toxin A/C domain Pkinase_Tyr PF07714.17 OQR84649.1 - 1.9e-32 112.6 0.0 2.5e-32 112.2 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OQR84649.1 - 4.7e-31 108.1 0.0 5.7e-31 107.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 OQR84649.1 - 0.12 11.1 0.0 0.17 10.6 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase RabGAP-TBC PF00566.18 OQR84654.1 - 1.9e-60 204.2 0.3 8.7e-60 202.0 0.0 1.9 1 1 1 2 2 2 1 Rab-GTPase-TBC domain DUF577 PF04510.12 OQR84654.1 - 0.039 13.9 0.2 0.069 13.0 0.2 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF577) SNARE_assoc PF09335.11 OQR84655.1 - 4e-14 53.1 2.4 8.9e-14 52.0 1.9 1.9 2 0 0 2 2 2 1 SNARE associated Golgi protein DUF3464 PF11947.8 OQR84655.1 - 0.13 12.1 0.0 0.26 11.0 0.0 1.4 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 Ank_2 PF12796.7 OQR84693.1 - 5.3e-28 97.4 4.5 3.7e-10 40.3 0.1 3.9 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQR84693.1 - 8.7e-23 80.4 0.0 3.1e-06 27.6 0.0 4.6 3 1 1 4 4 4 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 OQR84693.1 - 1.6e-22 79.2 0.3 0.00013 22.2 0.1 6.6 1 1 6 7 7 7 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQR84693.1 - 2.7e-15 54.9 0.0 3.6 8.5 0.0 7.0 6 1 1 7 7 7 3 Ankyrin repeat DUF5049 PF16468.5 OQR84693.1 - 1.9e-13 50.1 5.5 0.044 13.7 0.0 6.7 1 1 6 7 7 7 4 Domain of unknown function (DUF5049) T4_Rnl2_C PF18043.1 OQR84693.1 - 0.00015 21.9 2.0 5.2 7.3 0.0 4.8 4 1 2 6 6 6 1 T4 RNA ligase 2 C-terminal FaeA PF04703.12 OQR84693.1 - 0.00062 20.1 1.9 0.19 12.1 0.3 3.4 2 2 1 3 3 3 1 FaeA-like protein Baculo_LEF5_C PF11792.8 OQR84693.1 - 0.0014 18.2 2.4 9.4 6.0 0.1 4.8 4 1 1 5 5 5 1 Baculoviridae late expression factor 5 C-terminal domain DUF3447 PF11929.8 OQR84693.1 - 0.0035 17.3 0.9 0.22 11.5 0.0 3.2 1 1 3 4 4 4 1 Domain of unknown function (DUF3447) Ank PF00023.30 OQR84693.1 - 0.0096 16.3 0.0 25 5.6 0.0 5.2 4 1 0 4 4 3 0 Ankyrin repeat SapB_1 PF05184.15 OQR84693.1 - 0.063 13.3 2.3 1.7e+02 2.3 0.0 5.2 6 0 0 6 6 6 0 Saposin-like type B, region 1 CBFB_NFYA PF02045.15 OQR84693.1 - 0.073 13.7 0.3 55 4.5 0.1 3.7 2 2 1 3 3 3 0 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B TBPIP PF07106.13 OQR84693.1 - 0.094 12.7 0.0 63 3.6 0.0 4.1 2 2 3 5 5 5 0 TBPIP/Hop2 winged helix domain HBS1_N PF08938.10 OQR84693.1 - 0.11 12.8 0.1 4.5 7.7 0.0 3.2 2 1 2 4 4 4 0 HBS1 N-terminus YqbF PF14553.6 OQR84693.1 - 0.35 10.7 7.5 1.3e+02 2.5 0.0 5.8 7 0 0 7 7 6 0 YqbF, hypothetical protein domain CEBP_ZZ PF16366.5 OQR84693.1 - 0.42 10.9 2.0 5.7 7.2 0.1 3.1 2 1 0 2 2 2 0 Cytoplasmic polyadenylation element-binding protein ZZ domain zf-C3Hc3H PF13891.6 OQR84693.1 - 1.2 9.6 5.3 5.5 7.4 0.1 3.9 5 1 0 5 5 5 0 Potential DNA-binding domain ubiquitin PF00240.23 OQR84704.1 - 0.012 15.3 0.1 0.028 14.2 0.1 1.7 1 0 0 1 1 1 0 Ubiquitin family Ubiquitin_4 PF18036.1 OQR84704.1 - 0.085 12.9 0.0 0.26 11.4 0.0 1.8 1 0 0 1 1 1 0 Ubiquitin-like domain HA PF03457.14 OQR84705.1 - 1.1e-05 25.7 0.1 0.12 12.7 0.0 2.1 2 0 0 2 2 2 2 Helicase associated domain Utp14 PF04615.13 OQR84706.1 - 1.4e-57 195.9 19.8 1.4e-57 195.9 19.8 1.2 1 1 0 1 1 1 1 Utp14 protein TraU PF06834.11 OQR84706.1 - 0.11 11.8 0.1 0.26 10.5 0.1 1.6 1 0 0 1 1 1 0 TraU protein DUF3881 PF12997.7 OQR84706.1 - 4.8 6.3 6.4 3.1 7.0 1.3 2.7 2 1 1 3 3 3 0 Domain of unknown function, E. rectale Gene description (DUF3881) DUF4419 PF14388.6 OQR84707.1 - 7.4e-06 25.6 0.1 1.2e-05 25.0 0.0 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF4419) PALP PF00291.25 OQR84708.1 - 1e-77 261.5 0.3 1.3e-77 261.2 0.3 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme ACT PF01842.25 OQR84708.1 - 0.0002 21.0 0.0 0.00037 20.2 0.0 1.4 1 0 0 1 1 1 1 ACT domain ACT_6 PF13740.6 OQR84708.1 - 0.071 13.1 0.0 0.15 12.0 0.0 1.5 1 0 0 1 1 1 0 ACT domain HA PF03457.14 OQR84709.1 - 3.5e-20 72.1 0.5 3.8e-09 36.7 0.2 2.1 2 0 0 2 2 2 2 Helicase associated domain DUF4419 PF14388.6 OQR84710.1 - 6.7e-14 52.0 0.0 7e-11 42.1 0.0 2.0 1 1 1 2 2 2 2 Domain of unknown function (DUF4419) URO-D PF01208.17 OQR84752.1 - 8.6e-124 413.2 0.0 1e-123 412.9 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen decarboxylase (URO-D) Tup_N PF08581.10 OQR84753.1 - 0.0041 17.4 2.2 0.0041 17.4 2.2 5.1 1 1 3 5 5 5 2 Tup N-terminal Gon7 PF08738.10 OQR84753.1 - 0.01 15.9 0.4 0.01 15.9 0.4 3.1 3 0 0 3 3 3 0 Gon7 family DUF910 PF06014.11 OQR84753.1 - 0.024 14.6 0.4 0.1 12.6 0.0 2.4 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF910) LPP PF04728.13 OQR84753.1 - 0.052 13.9 15.2 11 6.5 0.4 6.1 4 1 2 6 6 6 0 Lipoprotein leucine-zipper Tox-GHH PF15636.6 OQR84753.1 - 0.062 13.3 4.3 0.18 11.8 4.3 1.8 1 0 0 1 1 1 0 GHH signature containing HNH/Endo VII superfamily nuclease toxin Baculo_PEP_C PF04513.12 OQR84753.1 - 0.74 9.9 20.3 1.1 9.3 4.2 3.7 2 2 2 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1664 PF07889.12 OQR84753.1 - 1.2 9.2 24.7 0.094 12.8 5.7 4.4 1 1 4 5 5 5 0 Protein of unknown function (DUF1664) TPR_MLP1_2 PF07926.12 OQR84753.1 - 3.7 7.6 37.1 5 7.2 5.0 4.3 1 1 4 5 5 5 0 TPR/MLP1/MLP2-like protein RasGAP_C PF03836.15 OQR84753.1 - 6.2 7.0 19.6 0.17 12.0 5.4 3.4 1 1 0 2 2 2 0 RasGAP C-terminus DUF3037 PF11236.8 OQR84753.1 - 6.9 7.1 14.1 0.13 12.6 2.2 3.2 2 1 2 4 4 4 0 Protein of unknown function (DUF3037) Actin PF00022.19 OQR84773.1 - 2.8e-78 263.4 0.0 1.3e-77 261.1 0.0 1.8 1 1 0 1 1 1 1 Actin TRP PF06011.12 OQR84804.1 - 6.4e-05 21.9 5.1 6.4e-05 21.9 5.1 2.4 2 0 0 2 2 2 2 Transient receptor potential (TRP) ion channel Ephrin_rec_like PF07699.13 OQR84804.1 - 0.00021 21.0 10.7 0.016 15.0 3.5 2.7 2 0 0 2 2 2 2 Putative ephrin-receptor like NCD3G PF07562.14 OQR84804.1 - 0.028 14.4 9.8 0.064 13.2 0.7 2.6 2 0 0 2 2 2 0 Nine Cysteines Domain of family 3 GPCR AMP-binding PF00501.28 OQR84859.1 - 1.1e-18 67.1 0.0 1.3e-18 66.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme Ank_2 PF12796.7 OQR84860.1 - 3e-25 88.6 25.1 6.9e-09 36.2 2.0 4.9 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQR84860.1 - 1.6e-20 73.2 20.2 1e-05 26.0 0.2 7.0 5 1 4 9 9 9 6 Ankyrin repeats (many copies) Ank_5 PF13857.6 OQR84860.1 - 5.2e-17 61.7 19.8 0.0043 17.3 0.1 8.3 3 2 6 9 9 9 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQR84860.1 - 1.2e-12 46.8 6.9 0.97 10.2 0.0 8.8 9 0 0 9 9 9 3 Ankyrin repeat Cas_Cas1 PF01867.16 OQR84860.1 - 4e-05 22.9 1.0 0.0091 15.2 0.1 2.3 1 1 1 2 2 2 2 CRISPR associated protein Cas1 DUF5049 PF16468.5 OQR84860.1 - 0.00037 20.3 1.0 12 5.9 0.0 5.7 2 1 4 6 6 6 1 Domain of unknown function (DUF5049) Ank PF00023.30 OQR84860.1 - 0.018 15.5 8.9 36 5.0 0.1 7.0 5 1 4 9 9 9 0 Ankyrin repeat Sld5 PF05916.11 OQR84906.1 - 1.4e-10 41.6 0.1 1.8e-10 41.3 0.1 1.2 1 0 0 1 1 1 1 GINS complex protein Pkinase PF00069.25 OQR84974.1 - 3.3e-15 56.2 0.1 6.3e-15 55.3 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQR84974.1 - 1.1e-13 51.2 0.0 1.6e-13 50.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Apo-VLDL-II PF05418.11 OQR84974.1 - 0.069 13.7 0.1 0.14 12.8 0.1 1.4 1 0 0 1 1 1 0 Apovitellenin I (Apo-VLDL-II) WD40 PF00400.32 OQR85019.1 - 1.1e-17 64.1 12.8 3.2e-05 24.6 0.0 6.4 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OQR85019.1 - 0.0029 17.9 0.3 3.3 8.1 0.0 3.3 2 2 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain tRNA-synt_1d PF00750.19 OQR85056.1 - 2.4e-69 233.9 0.0 3.7e-69 233.3 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (R) Ribosomal_L1 PF00687.21 OQR85056.1 - 3.4e-51 173.9 0.0 5.8e-51 173.1 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family DALR_1 PF05746.15 OQR85056.1 - 3e-20 72.6 0.2 8.4e-20 71.1 0.0 1.9 2 0 0 2 2 2 1 DALR anticodon binding domain tRNA-synt_1 PF00133.22 OQR85056.1 - 0.00025 19.5 0.0 0.0016 16.8 0.0 2.1 2 1 0 2 2 2 1 tRNA synthetases class I (I, L, M and V) tRNA-synt_1e PF01406.19 OQR85056.1 - 0.01 15.2 0.0 0.017 14.5 0.0 1.2 1 0 0 1 1 1 0 tRNA synthetases class I (C) catalytic domain Arg_tRNA_synt_N PF03485.16 OQR85056.1 - 0.064 13.9 0.0 0.26 11.9 0.0 2.1 1 0 0 1 1 1 0 Arginyl tRNA synthetase N terminal domain MoCF_biosynth PF00994.24 OQR85056.1 - 0.12 12.0 0.0 3.1 7.4 0.0 2.8 3 0 0 3 3 3 0 Probable molybdopterin binding domain FRG1 PF06229.12 OQR85081.1 - 0.00014 21.6 0.0 2.2 8.0 0.0 3.8 2 2 0 3 3 3 2 FRG1-like domain RicinB_lectin_2 PF14200.6 OQR85081.1 - 0.0061 17.3 4.3 11 6.8 0.0 3.9 2 2 3 5 5 5 3 Ricin-type beta-trefoil lectin domain-like zf-UBR PF02207.20 OQR85081.1 - 0.03 14.5 1.8 4.7 7.5 0.0 3.8 4 0 0 4 4 4 0 Putative zinc finger in N-recognin (UBR box) SprB PF13573.6 OQR85081.1 - 0.068 12.9 0.0 6.7 6.6 0.0 3.0 2 0 0 2 2 2 0 SprB repeat CID_GANP PF16766.5 OQR85081.1 - 0.098 12.9 1.4 31 4.8 0.0 3.8 4 0 0 4 4 4 0 Binding region of GANP to ENY2 Methyltransf_23 PF13489.6 OQR85082.1 - 5.4e-08 32.9 0.0 7.1e-08 32.5 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OQR85082.1 - 0.0053 17.4 0.0 0.011 16.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain NNMT_PNMT_TEMT PF01234.17 OQR85082.1 - 0.011 14.9 0.1 0.035 13.3 0.0 1.8 1 1 1 2 2 2 0 NNMT/PNMT/TEMT family Methyltransf_12 PF08242.12 OQR85082.1 - 0.031 15.0 0.0 0.059 14.1 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_8 PF05148.15 OQR85082.1 - 0.034 14.0 0.0 0.037 13.9 0.0 1.2 1 0 0 1 1 1 0 Hypothetical methyltransferase Methyltransf_11 PF08241.12 OQR85082.1 - 0.12 13.0 0.0 0.26 12.0 0.0 1.6 2 0 0 2 2 2 0 Methyltransferase domain GDP_Man_Dehyd PF16363.5 OQR85096.1 - 3.5e-40 138.4 0.0 6e-40 137.6 0.0 1.3 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 OQR85096.1 - 1.1e-35 123.2 0.0 1.5e-35 122.8 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 OQR85096.1 - 0.00049 19.4 0.0 0.0017 17.6 0.0 1.8 1 1 0 1 1 1 1 Male sterility protein RmlD_sub_bind PF04321.17 OQR85096.1 - 0.026 13.6 0.1 0.03 13.4 0.1 1.5 1 1 0 1 1 1 0 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 OQR85096.1 - 0.21 10.7 0.0 1.6 7.8 0.0 2.0 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein Annexin PF00191.20 OQR85099.1 - 4.2e-30 103.6 2.3 5e-09 36.1 0.2 4.1 4 0 0 4 4 4 4 Annexin Annexin_like PF18411.1 OQR85099.1 - 0.036 14.3 0.0 0.084 13.1 0.0 1.6 1 0 0 1 1 1 0 Annexin-like domain DUF2255 PF10012.9 OQR85099.1 - 0.17 12.0 0.2 9.3 6.4 0.0 2.4 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2255) Pro_isomerase PF00160.21 OQR85113.1 - 1.8e-30 106.3 0.0 2.4e-30 105.9 0.0 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RRM_1 PF00076.22 OQR85113.1 - 0.12 12.2 0.0 0.27 11.1 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Anoctamin PF04547.12 OQR85122.1 - 5.1e-73 246.4 1.8 5.7e-73 246.3 1.8 1.0 1 0 0 1 1 1 1 Calcium-activated chloride channel IspA PF04279.15 OQR85126.1 - 0.08 13.1 10.1 0.046 13.9 6.0 2.0 1 1 1 2 2 2 0 Intracellular septation protein A Pkinase PF00069.25 OQR85128.1 - 1.2e-38 133.0 0.1 1.3e-37 129.6 0.1 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQR85128.1 - 8.7e-16 58.0 0.0 1.8e-15 57.0 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OQR85128.1 - 0.011 14.5 0.0 0.016 14.0 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase ROS_MUCR PF05443.11 OQR85128.1 - 0.049 13.7 0.1 0.099 12.7 0.1 1.4 1 0 0 1 1 1 0 ROS/MUCR transcriptional regulator protein Paramyx_P_V_C PF03210.13 OQR85128.1 - 0.069 12.9 0.0 0.18 11.5 0.0 1.6 2 0 0 2 2 2 0 Paramyxovirus P/V phosphoprotein C-terminal Band_7 PF01145.25 OQR85129.1 - 2.6e-19 69.9 0.0 2.6e-19 69.9 0.0 3.1 1 1 0 2 2 2 1 SPFH domain / Band 7 family Band_7_1 PF13421.6 OQR85129.1 - 0.0033 17.2 0.1 0.0033 17.2 0.1 2.3 2 0 0 2 2 2 1 SPFH domain-Band 7 family Imm50 PF15594.6 OQR85129.1 - 0.14 12.4 1.0 0.44 10.8 0.0 2.3 2 1 1 3 3 3 0 Immunity protein 50 E1_UFD PF09358.10 OQR85129.1 - 4.6 8.0 6.0 51 4.7 5.0 3.2 1 1 1 2 2 2 0 Ubiquitin fold domain Band_7 PF01145.25 OQR85130.1 - 1.3e-22 80.6 0.0 1.3e-22 80.6 0.0 2.2 3 0 0 3 3 3 1 SPFH domain / Band 7 family Band_7_1 PF13421.6 OQR85130.1 - 0.012 15.4 0.0 0.023 14.4 0.0 1.4 1 0 0 1 1 1 0 SPFH domain-Band 7 family DUF3629 PF12302.8 OQR85130.1 - 0.3 10.5 4.6 0.42 10.0 4.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3629) DnaJ PF00226.31 OQR85132.1 - 2e-23 82.3 0.8 3.4e-23 81.5 0.8 1.4 1 0 0 1 1 1 1 DnaJ domain Tmemb_185A PF10269.9 OQR85132.1 - 8.9e-20 71.4 41.0 8.3e-15 55.1 25.2 3.0 1 1 1 2 2 2 2 Transmembrane Fragile-X-F protein PgaD PF13994.6 OQR85132.1 - 2.1 8.4 6.3 0.62 10.1 2.0 2.2 2 0 0 2 2 2 0 PgaD-like protein PhyH PF05721.13 OQR85133.1 - 4.7e-12 46.6 0.1 5.5e-11 43.1 0.1 2.2 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) 2OG-FeII_Oxy_5 PF13759.6 OQR85133.1 - 0.019 15.4 0.0 0.039 14.4 0.0 1.5 1 0 0 1 1 1 0 Putative 2OG-Fe(II) oxygenase Aminotran_5 PF00266.19 OQR85134.1 - 2e-24 86.2 0.0 4.6e-24 85.1 0.0 1.6 1 1 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 OQR85134.1 - 7.6e-08 31.3 0.0 1.1e-07 30.8 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 OQR85134.1 - 3e-07 29.9 0.0 4.4e-07 29.4 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II SepSecS PF05889.13 OQR85134.1 - 0.026 13.2 0.0 0.039 12.6 0.0 1.2 1 0 0 1 1 1 0 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS Wzy_C PF04932.15 OQR85135.1 - 0.058 13.0 3.6 0.083 12.5 3.6 1.3 1 0 0 1 1 1 0 O-Antigen ligase Pkinase PF00069.25 OQR85140.1 - 1.8e-05 24.3 0.1 1.8e-05 24.3 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 OQR85140.1 - 3.4e-05 22.8 0.1 3.5e-05 22.7 0.1 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 OQR85140.1 - 0.021 14.2 0.4 0.027 13.8 0.4 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OQR85140.1 - 0.053 13.4 0.2 0.059 13.3 0.2 1.1 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase_Tyr PF07714.17 OQR85140.1 - 0.08 12.2 0.1 0.08 12.2 0.1 1.1 1 0 0 1 1 1 0 Protein tyrosine kinase AAA PF00004.29 OQR85152.1 - 2.5e-20 73.2 0.2 1.2e-19 71.0 0.2 2.0 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 OQR85152.1 - 2.4e-05 24.8 0.0 5.1e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.14 OQR85152.1 - 6.7e-05 22.9 0.0 0.00026 21.0 0.0 2.1 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 OQR85152.1 - 0.00018 21.3 0.1 0.00036 20.3 0.1 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain DUF815 PF05673.13 OQR85152.1 - 0.00076 18.7 0.0 0.0014 17.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) ABC_tran PF00005.27 OQR85152.1 - 0.0015 19.1 0.0 0.0038 17.7 0.0 1.7 1 0 0 1 1 1 1 ABC transporter AAA_22 PF13401.6 OQR85152.1 - 0.0027 18.0 0.0 0.0075 16.5 0.0 1.9 1 1 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 OQR85152.1 - 0.0046 17.3 0.1 0.026 14.9 0.0 2.3 2 0 0 2 2 2 1 RNA helicase AAA_7 PF12775.7 OQR85152.1 - 0.0048 16.4 0.0 0.011 15.3 0.0 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_11 PF13086.6 OQR85152.1 - 0.0049 16.7 0.5 0.011 15.5 0.5 1.7 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 OQR85152.1 - 0.0081 16.7 0.0 0.022 15.3 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 OQR85152.1 - 0.0095 16.1 0.0 0.029 14.5 0.0 1.9 2 0 0 2 2 1 1 AAA domain AAA_28 PF13521.6 OQR85152.1 - 0.0097 16.2 0.0 0.023 15.0 0.0 1.7 2 0 0 2 2 1 1 AAA domain AAA_30 PF13604.6 OQR85152.1 - 0.0099 15.6 0.0 0.019 14.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 OQR85152.1 - 0.012 15.9 0.1 0.027 14.8 0.1 1.5 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 OQR85152.1 - 0.024 14.3 0.0 0.048 13.4 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein NACHT PF05729.12 OQR85152.1 - 0.027 14.4 0.1 0.099 12.6 0.1 2.1 1 1 0 1 1 1 0 NACHT domain AAA_14 PF13173.6 OQR85152.1 - 0.031 14.3 0.1 0.11 12.6 0.0 1.9 2 0 0 2 2 2 0 AAA domain Bac_DnaA PF00308.18 OQR85152.1 - 0.032 14.1 0.0 0.068 13.0 0.0 1.5 1 0 0 1 1 1 0 Bacterial dnaA protein Viral_helicase1 PF01443.18 OQR85152.1 - 0.046 13.5 0.0 0.12 12.1 0.0 1.7 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase TsaE PF02367.17 OQR85152.1 - 0.046 13.7 0.1 0.097 12.7 0.1 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Zeta_toxin PF06414.12 OQR85152.1 - 0.048 12.9 0.0 0.11 11.7 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin cobW PF02492.19 OQR85152.1 - 0.052 13.1 0.2 0.38 10.3 0.0 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_24 PF13479.6 OQR85152.1 - 0.1 12.3 0.2 0.55 9.9 0.1 2.1 2 0 0 2 2 2 0 AAA domain Mg_chelatase PF01078.21 OQR85152.1 - 0.12 11.7 0.1 0.25 10.7 0.1 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI MFS_1 PF07690.16 OQR85153.1 - 4.5e-29 101.5 54.1 7.8e-22 77.7 31.6 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily RELT PF12606.8 OQR85153.1 - 0.098 11.7 0.1 0.33 10.0 0.1 2.0 1 0 0 1 1 1 0 Tumour necrosis factor receptor superfamily member 19 DUF3530 PF12048.8 OQR85156.1 - 0.13 11.7 4.1 0.15 11.4 4.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3530) MIT PF04212.18 OQR85157.1 - 1.4e-05 25.0 1.3 1.4e-05 25.0 1.3 2.7 3 0 0 3 3 3 1 MIT (microtubule interacting and transport) domain DUF3856 PF12968.7 OQR85157.1 - 0.0071 16.4 0.9 0.079 13.0 0.1 2.3 2 0 0 2 2 2 1 Domain of Unknown Function (DUF3856) DUF1759 PF03564.15 OQR85157.1 - 0.02 14.8 2.5 0.041 13.8 0.1 2.4 2 1 1 3 3 3 0 Protein of unknown function (DUF1759) MbeD_MobD PF04899.12 OQR85157.1 - 0.076 13.1 0.2 0.17 12.0 0.2 1.5 1 0 0 1 1 1 0 MbeD/MobD like Aida_N PF08910.10 OQR85157.1 - 0.12 12.8 0.4 0.12 12.8 0.4 2.0 2 1 0 2 2 2 0 Aida N-terminus DUF5113 PF17140.4 OQR85157.1 - 0.22 11.3 2.1 0.25 11.1 0.2 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF5113) Bacteriocin_IIc PF10439.9 OQR85157.1 - 0.33 11.1 5.5 0.58 10.3 5.5 1.4 1 0 0 1 1 1 0 Bacteriocin class II with double-glycine leader peptide ATG11 PF10377.9 OQR85157.1 - 1.4 9.0 4.9 0.24 11.4 0.5 1.9 2 0 0 2 2 2 0 Autophagy-related protein 11 MRG PF05712.13 OQR85158.1 - 2e-37 128.4 0.1 5.9e-37 126.9 0.1 1.8 2 0 0 2 2 2 1 MRG TP_methylase PF00590.20 OQR85158.1 - 3.6e-24 85.9 0.0 1.4e-23 83.9 0.0 2.1 1 1 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases Tudor-knot PF11717.8 OQR85158.1 - 9.4e-09 35.0 0.1 4e-08 33.0 0.0 2.1 2 0 0 2 2 2 1 RNA binding activity-knot of a chromodomain CDC45 PF02724.14 OQR85158.1 - 3.1 6.0 11.7 4.1 5.6 11.7 1.2 1 0 0 1 1 1 0 CDC45-like protein FAD-oxidase_C PF02913.19 OQR85182.1 - 5.3e-44 150.7 0.0 5.8e-44 150.6 0.0 1.0 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain Acp26Ab PF05777.12 OQR85182.1 - 0.035 14.7 0.0 0.058 14.0 0.0 1.3 1 0 0 1 1 1 0 Drosophila accessory gland-specific peptide 26Ab (Acp26Ab) Glyco_hydro_17 PF00332.18 OQR85184.1 - 3e-07 30.3 0.4 0.0051 16.4 0.1 2.3 2 0 0 2 2 2 2 Glycosyl hydrolases family 17 TMEM154 PF15102.6 OQR85184.1 - 0.98 9.3 5.0 1.6 8.6 5.0 1.4 1 0 0 1 1 1 0 TMEM154 protein family SOG2 PF10428.9 OQR85184.1 - 2.6 7.2 13.5 3.6 6.7 13.5 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein IncD PF17628.2 OQR85185.1 - 0.018 14.8 0.0 0.023 14.5 0.0 1.3 1 0 0 1 1 1 0 Inclusion membrane protein D NnrU PF07298.11 OQR85185.1 - 0.024 14.1 1.0 0.049 13.1 0.9 1.5 1 1 1 2 2 2 0 NnrU protein PDZ_6 PF17820.1 OQR85186.1 - 8.2e-07 28.8 0.0 1.7e-06 27.8 0.0 1.5 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 OQR85186.1 - 3.8e-05 24.0 0.0 6.7e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 PDZ domain PFU PF09070.11 OQR85188.1 - 4.2e-05 23.8 0.0 6.7 7.0 0.0 3.9 4 0 0 4 4 4 3 PFU (PLAA family ubiquitin binding) DUF960 PF06124.11 OQR85188.1 - 0.13 12.9 0.1 6 7.6 0.0 2.5 1 1 1 2 2 2 0 Staphylococcal protein of unknown function (DUF960) CPL PF08144.11 OQR85189.1 - 1.5e-14 54.5 6.1 2.6e-13 50.5 0.0 4.2 3 3 0 3 3 3 1 CPL (NUC119) domain PUF PF00806.19 OQR85189.1 - 5.7e-07 28.9 0.0 0.12 12.1 0.0 4.6 4 0 0 4 4 4 3 Pumilio-family RNA binding repeat VSG_B PF13206.6 OQR85189.1 - 0.023 14.0 3.3 0.049 12.9 3.3 1.5 1 0 0 1 1 1 0 Trypanosomal VSG domain p450 PF00067.22 OQR85190.1 - 2.7e-51 174.8 1.3 3.2e-51 174.5 1.3 1.0 1 0 0 1 1 1 1 Cytochrome P450 Prot_ATP_OB_N PF17758.1 OQR85190.1 - 0.16 11.7 0.0 0.33 10.6 0.0 1.5 1 0 0 1 1 1 0 Proteasomal ATPase OB N-terminal domain Peptidase_C1 PF00112.23 OQR85192.1 - 4e-61 206.9 0.2 4.5e-61 206.7 0.2 1.0 1 0 0 1 1 1 1 Papain family cysteine protease AlgF PF11182.8 OQR85192.1 - 0.049 13.4 0.1 0.077 12.8 0.1 1.3 1 0 0 1 1 1 0 Alginate O-acetyl transferase AlgF FH2 PF02181.23 OQR85193.1 - 1e-79 268.4 4.1 1.5e-79 267.8 4.1 1.2 1 0 0 1 1 1 1 Formin Homology 2 Domain CCDC53 PF10152.9 OQR85193.1 - 1e-24 87.7 24.3 1.6e-13 51.3 1.6 4.2 3 1 2 5 5 5 3 Subunit CCDC53 of WASH complex Nitroreductase PF00881.24 OQR85193.1 - 0.056 13.5 0.0 11 6.1 0.0 2.8 2 1 1 3 3 3 0 Nitroreductase family SKG6 PF08693.10 OQR85194.1 - 0.0007 19.0 0.9 0.0016 17.8 0.9 1.6 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Alpha_GJ PF03229.13 OQR85194.1 - 0.23 12.0 10.2 0.057 14.0 3.7 2.3 2 0 0 2 2 2 0 Alphavirus glycoprotein J Syndecan PF01034.20 OQR85195.1 - 0.051 13.5 0.0 0.13 12.2 0.0 1.6 1 0 0 1 1 1 0 Syndecan domain DUF5305 PF17231.2 OQR85195.1 - 0.062 12.7 0.0 0.1 12.0 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5305) DUF4366 PF14283.6 OQR85195.1 - 6.1 6.9 9.2 2.2 8.3 4.2 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4366) Oxidored_FMN PF00724.20 OQR85197.1 - 1.7e-179 596.4 0.0 1e-88 297.9 0.0 2.0 2 0 0 2 2 2 2 NADH:flavin oxidoreductase / NADH oxidase family DUF4999 PF16390.5 OQR85197.1 - 0.005 17.0 0.0 0.97 9.7 0.0 2.5 2 0 0 2 2 2 2 Domain of unknown function His_biosynth PF00977.21 OQR85197.1 - 0.056 12.9 0.0 10 5.5 0.0 2.9 3 0 0 3 3 3 0 Histidine biosynthesis protein Peptidase_U32 PF01136.19 OQR85197.1 - 0.15 11.2 0.0 17 4.5 0.0 2.2 2 0 0 2 2 2 0 Peptidase family U32 Mob1_phocein PF03637.17 OQR85199.1 - 3.8e-75 251.5 0.0 4.5e-75 251.3 0.0 1.0 1 0 0 1 1 1 1 Mob1/phocein family ABC2_membrane PF01061.24 OQR85200.1 - 7.8e-33 113.7 31.5 7.8e-33 113.7 31.5 1.9 2 0 0 2 2 2 1 ABC-2 type transporter ABC2_membrane_3 PF12698.7 OQR85200.1 - 0.013 14.7 25.8 0.044 12.9 25.8 1.9 1 1 0 1 1 1 0 ABC-2 family transporter protein LRR_6 PF13516.6 OQR85203.1 - 3.2e-12 45.5 21.8 0.017 15.2 0.1 5.7 5 0 0 5 5 5 5 Leucine Rich repeat DUF4476 PF14771.6 OQR85203.1 - 7e-05 23.1 2.2 0.0026 18.0 0.1 3.0 2 1 0 2 2 2 1 Domain of unknown function (DUF4476) LRR_1 PF00560.33 OQR85203.1 - 0.017 15.6 4.9 4.8 8.1 0.2 4.8 4 0 0 4 4 4 0 Leucine Rich Repeat LRR_4 PF12799.7 OQR85203.1 - 0.78 10.3 12.0 0.63 10.6 2.2 3.7 2 1 2 4 4 4 0 Leucine Rich repeats (2 copies) HoxA13_N PF12284.8 OQR85204.1 - 0.24 12.0 0.3 0.41 11.3 0.3 1.2 1 0 0 1 1 1 0 Hox protein A13 N terminal GAF PF01590.26 OQR85205.1 - 6e-18 65.8 0.7 1.2e-07 32.4 0.2 2.2 2 0 0 2 2 2 2 GAF domain GAF_3 PF13492.6 OQR85205.1 - 0.004 17.5 0.0 0.038 14.3 0.0 2.2 2 1 0 2 2 2 1 GAF domain Peptidase_C24 PF03510.14 OQR85205.1 - 0.015 15.8 1.0 0.16 12.5 0.3 2.5 3 0 0 3 3 3 0 2C endopeptidase (C24) cysteine protease family EF-hand_7 PF13499.6 OQR85206.1 - 3.1e-21 75.6 12.6 2.1e-11 44.1 0.3 3.5 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_1 PF00036.32 OQR85206.1 - 2.2e-20 70.6 22.7 6.2e-08 31.6 0.8 5.1 6 0 0 6 6 6 4 EF hand EF-hand_6 PF13405.6 OQR85206.1 - 9.5e-20 68.8 12.1 1.1e-05 25.0 0.2 5.2 5 0 0 5 5 5 4 EF-hand domain EF-hand_8 PF13833.6 OQR85206.1 - 3.8e-15 55.5 12.2 1.5e-08 34.4 1.0 4.3 3 1 1 4 4 4 2 EF-hand domain pair EF-hand_5 PF13202.6 OQR85206.1 - 2.7e-13 48.7 13.6 9.1e-06 24.9 0.2 4.8 5 0 0 5 5 5 3 EF hand SPARC_Ca_bdg PF10591.9 OQR85206.1 - 4.6e-07 30.1 1.1 0.003 17.9 0.3 2.5 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_9 PF14658.6 OQR85206.1 - 7.7e-05 22.9 0.3 0.017 15.5 0.1 2.6 2 0 0 2 2 2 1 EF-hand domain EF-hand_4 PF12763.7 OQR85206.1 - 0.00086 19.2 4.0 0.1 12.5 0.2 2.7 3 0 0 3 3 3 2 Cytoskeletal-regulatory complex EF hand MotA_activ PF09114.10 OQR85206.1 - 0.0062 16.6 0.0 0.014 15.5 0.0 1.6 1 0 0 1 1 1 1 Transcription factor MotA, activation domain p25-alpha PF05517.12 OQR85206.1 - 0.015 15.4 3.9 0.18 12.0 0.1 2.8 4 0 0 4 4 4 0 p25-alpha PhoLip_ATPase_N PF16209.5 OQR85207.1 - 7.9e-23 79.9 1.1 7.9e-23 79.9 1.1 2.3 2 0 0 2 2 2 1 Phospholipid-translocating ATPase N-terminal Cation_ATPase PF13246.6 OQR85207.1 - 1.3e-10 41.2 0.0 5.7e-09 35.9 0.0 2.6 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 OQR85207.1 - 5.9e-07 30.0 0.0 7.6e-06 26.4 0.0 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 OQR85207.1 - 2.6e-06 27.1 0.0 1.2e-05 25.0 0.0 2.1 1 1 0 1 1 1 1 E1-E2 ATPase DUF4133 PF13571.6 OQR85207.1 - 1.6 9.1 3.4 19 5.6 0.5 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4133) Acyltransf_C PF16076.5 OQR85213.1 - 3.9e-07 30.1 0.3 7.8e-07 29.1 0.1 1.7 2 0 0 2 2 2 1 Acyltransferase C-terminus Acyltransferase PF01553.21 OQR85213.1 - 0.00031 20.4 0.0 0.00046 19.8 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase DUF1647 PF07801.11 OQR85213.1 - 0.13 12.1 0.0 0.32 10.7 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1647) zf-C3HC4_3 PF13920.6 OQR85214.1 - 6.2e-11 42.0 16.3 1.4e-10 40.9 16.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 OQR85214.1 - 6.7e-06 25.9 15.1 6.7e-06 25.9 15.1 1.9 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 OQR85214.1 - 0.0012 19.1 18.4 0.0031 17.8 18.4 1.8 1 0 0 1 1 1 1 Ring finger domain DUF4796 PF16044.5 OQR85214.1 - 2.1 7.9 9.1 3.9 7.0 4.4 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4796) zf-RING_11 PF17123.5 OQR85214.1 - 4.5 7.1 15.7 1.6 8.5 8.2 3.0 2 1 1 3 3 3 0 RING-like zinc finger ABC_membrane PF00664.23 OQR85217.1 - 8.9e-48 163.3 18.0 1.2e-47 162.9 18.0 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 OQR85217.1 - 1e-09 39.0 0.0 2.7e-09 37.7 0.0 1.7 1 0 0 1 1 1 1 ABC transporter AAA_29 PF13555.6 OQR85217.1 - 0.004 16.8 0.0 0.0092 15.7 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 OQR85217.1 - 0.03 14.2 0.0 0.056 13.3 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase G-alpha PF00503.20 OQR85217.1 - 0.14 11.3 0.0 0.22 10.7 0.0 1.2 1 0 0 1 1 1 0 G-protein alpha subunit Pirin_C PF05726.13 OQR85219.1 - 6.6e-20 71.4 0.0 1.2e-19 70.6 0.0 1.5 1 0 0 1 1 1 1 Pirin C-terminal cupin domain Pirin PF02678.16 OQR85219.1 - 1.9e-19 69.6 0.1 3.7e-19 68.7 0.1 1.5 1 0 0 1 1 1 1 Pirin Pirin_C_2 PF17954.1 OQR85219.1 - 0.16 12.2 0.0 0.25 11.5 0.0 1.4 1 0 0 1 1 1 0 Quercetinase C-terminal cupin domain Snf7 PF03357.21 OQR85223.1 - 1.5e-30 106.1 28.6 1.7e-30 105.9 28.6 1.0 1 0 0 1 1 1 1 Snf7 Arm-DNA-bind_3 PF13356.6 OQR85223.1 - 0.36 11.2 2.2 0.87 10.0 2.2 1.6 1 0 0 1 1 1 0 Arm DNA-binding domain RNA_lig_T4_1 PF09511.10 OQR85223.1 - 0.38 10.6 4.0 0.39 10.5 2.7 1.5 1 1 1 2 2 2 0 RNA ligase DUF2828 PF11443.8 OQR85226.1 - 5.9e-48 163.4 1.0 5.5e-26 90.8 0.5 3.0 2 1 0 2 2 2 2 Domain of unknown function (DUF2828) DUF445 PF04286.12 OQR85230.1 - 0.0023 17.8 6.9 0.2 11.4 7.7 2.1 1 1 1 2 2 2 1 Protein of unknown function (DUF445) RdRP PF05183.12 OQR85230.1 - 0.0047 15.6 2.7 0.0061 15.3 2.7 1.1 1 0 0 1 1 1 1 RNA dependent RNA polymerase RTTN_N PF14726.6 OQR85230.1 - 0.0053 17.5 8.1 0.017 15.9 2.3 2.4 1 1 1 2 2 2 1 Rotatin, an armadillo repeat protein, centriole functioning CotH PF08757.11 OQR85230.1 - 0.0058 16.2 3.9 0.51 9.8 0.3 2.7 1 1 2 3 3 3 2 CotH kinase protein HEAT_2 PF13646.6 OQR85230.1 - 0.012 16.0 0.4 0.12 12.8 0.1 2.4 1 1 0 2 2 2 0 HEAT repeats SapB_1 PF05184.15 OQR85230.1 - 0.027 14.5 3.7 0.19 11.8 0.0 3.6 2 2 3 5 5 5 0 Saposin-like type B, region 1 GerD PF17898.1 OQR85230.1 - 0.036 14.0 9.5 0.81 9.7 3.5 3.7 1 1 2 3 3 3 0 Spore germination GerD central core domain CtsR_C PF17727.1 OQR85230.1 - 0.037 14.1 1.1 0.29 11.3 0.0 2.7 2 1 0 2 2 2 0 CtsR C-terminal dimerization domain T6PP_N PF18572.1 OQR85230.1 - 0.049 13.5 4.3 0.22 11.4 0.4 2.6 1 1 1 2 2 2 0 Trehalose-6-phosphate phosphatase N-terminal helical bundle domain PqqD PF05402.12 OQR85230.1 - 0.054 13.8 0.3 18 5.7 0.0 3.3 3 1 1 4 4 3 0 Coenzyme PQQ synthesis protein D (PqqD) DnaGprimase_HBD PF16730.5 OQR85230.1 - 0.066 13.3 1.8 0.5 10.5 0.4 2.4 1 1 1 2 2 2 0 DnaG-primase C-terminal, helicase-binding domain DnaI_N PF07319.11 OQR85230.1 - 0.085 13.5 6.3 17 6.2 1.5 3.6 1 1 3 4 4 4 0 Primosomal protein DnaI N-terminus Nif11 PF07862.11 OQR85230.1 - 0.1 12.9 0.5 3.3 8.1 0.0 3.5 3 1 0 3 3 3 0 Nif11 domain L_biotic_typeA PF04604.13 OQR85230.1 - 0.12 12.2 0.3 1.9 8.4 0.0 2.8 2 0 0 2 2 2 0 Type-A lantibiotic Globin PF00042.22 OQR85230.1 - 0.13 12.8 0.3 0.85 10.2 0.0 2.4 2 1 0 2 2 2 0 Globin DUF3333 PF11812.8 OQR85230.1 - 0.23 11.7 4.7 0.25 11.5 0.6 2.6 1 1 2 3 3 3 0 Domain of unknown function (DUF3333) ATP-synt_G PF04718.15 OQR85230.1 - 0.52 11.2 6.6 2.6 8.9 1.3 2.7 1 1 1 2 2 2 0 Mitochondrial ATP synthase g subunit DUF3819 PF12842.7 OQR85230.1 - 0.78 9.7 11.5 3.9 7.4 0.1 2.8 1 1 2 3 3 3 0 Domain of unknown function (DUF3819) Vps39_2 PF10367.9 OQR85230.1 - 9 6.8 7.9 6.1 7.3 0.9 2.5 2 1 0 2 2 2 0 Vacuolar sorting protein 39 domain 2 Anoctamin PF04547.12 OQR85236.1 - 4.8e-79 266.3 19.9 4.8e-79 266.3 19.9 2.8 2 1 0 2 2 2 1 Calcium-activated chloride channel Anoct_dimer PF16178.5 OQR85236.1 - 0.011 15.5 0.0 0.023 14.4 0.0 1.6 1 0 0 1 1 1 0 Dimerisation domain of Ca+-activated chloride-channel, anoctamin DUF2157 PF09925.9 OQR85236.1 - 0.86 9.4 0.0 0.86 9.4 0.0 4.0 4 1 0 4 4 4 0 Predicted membrane protein (DUF2157) PAN_4 PF14295.6 OQR85289.1 - 2.4e-20 72.2 38.5 3.9e-08 33.1 5.3 4.4 4 0 0 4 4 4 4 PAN domain PAN_1 PF00024.26 OQR85289.1 - 9.9e-16 57.5 17.8 2.7e-05 24.0 1.4 4.2 3 1 1 4 4 4 3 PAN domain Dmrt1 PF12374.8 OQR85289.1 - 0.0077 16.7 1.6 10 6.6 0.0 3.3 3 0 0 3 3 3 2 Double-sex mab3 related transcription factor 1 Glyco_hyd_101C PF17451.2 OQR85289.1 - 0.024 14.9 0.8 7.1 7.0 0.0 2.8 3 0 0 3 3 3 0 Glycosyl hydrolase 101 beta sandwich domain Dynamin_M PF01031.20 OQR85299.1 - 1.7e-09 37.3 0.0 3.4e-09 36.3 0.0 1.5 1 0 0 1 1 1 1 Dynamin central region GED PF02212.18 OQR85299.1 - 2e-07 31.1 0.5 2e-07 31.1 0.5 2.3 2 0 0 2 2 2 1 Dynamin GTPase effector domain DUF5638 PF18688.1 OQR85299.1 - 0.023 15.0 0.3 0.1 12.9 0.2 2.2 1 1 0 1 1 1 0 Family of unknown function (DUF5638) S-AdoMet_synt_C PF02773.16 OQR85299.1 - 0.066 13.2 0.2 0.16 11.9 0.2 1.6 1 0 0 1 1 1 0 S-adenosylmethionine synthetase, C-terminal domain Dynamin_M PF01031.20 OQR85300.1 - 7.5e-35 120.5 0.2 1e-26 93.9 0.0 2.7 3 0 0 3 3 3 2 Dynamin central region Dynamin_N PF00350.23 OQR85300.1 - 2.5e-33 115.5 0.2 4.8e-33 114.6 0.2 1.5 1 0 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.23 OQR85300.1 - 4.7e-07 29.9 0.1 2.2e-06 27.7 0.1 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase IIGP PF05049.13 OQR85300.1 - 0.00055 19.1 0.0 1.5 7.8 0.0 3.3 3 0 0 3 3 3 2 Interferon-inducible GTPase (IIGP) AAA_29 PF13555.6 OQR85300.1 - 0.072 12.9 0.2 0.27 11.0 0.1 2.0 2 0 0 2 2 2 0 P-loop containing region of AAA domain ABC_tran PF00005.27 OQR85300.1 - 0.095 13.2 0.0 0.22 12.0 0.0 1.7 1 0 0 1 1 1 0 ABC transporter Tudor_4 PF18358.1 OQR85300.1 - 0.17 11.5 0.6 0.68 9.6 0.1 2.3 3 0 0 3 3 3 0 Histone methyltransferase Tudor domain FlgH PF02107.16 OQR85301.1 - 0.026 14.1 0.0 0.035 13.7 0.0 1.2 1 0 0 1 1 1 0 Flagellar L-ring protein RNA_pol_Rpc4 PF05132.14 OQR85301.1 - 0.098 13.1 0.4 0.15 12.5 0.4 1.2 1 0 0 1 1 1 0 RNA polymerase III RPC4 ABC2_membrane PF01061.24 OQR85309.1 - 7.1e-20 71.3 18.1 1.1e-19 70.7 18.1 1.3 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.27 OQR85309.1 - 1e-11 45.5 0.0 1.6e-11 44.9 0.0 1.3 1 0 0 1 1 1 1 ABC transporter Zeta_toxin PF06414.12 OQR85309.1 - 0.014 14.7 0.0 0.027 13.8 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_16 PF13191.6 OQR85309.1 - 0.026 14.9 0.0 0.049 14.0 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain MMR_HSR1 PF01926.23 OQR85309.1 - 0.031 14.3 0.0 0.059 13.4 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase Dynamin_N PF00350.23 OQR85309.1 - 0.12 12.4 0.1 0.22 11.6 0.1 1.4 1 0 0 1 1 1 0 Dynamin family ABC2_membrane PF01061.24 OQR85310.1 - 2.9e-32 111.8 24.1 4.6e-32 111.1 24.1 1.3 1 0 0 1 1 1 1 ABC-2 type transporter PDR_CDR PF06422.12 OQR85310.1 - 0.0001 22.1 0.4 0.0001 22.1 0.4 2.3 2 0 0 2 2 2 1 CDR ABC transporter PDR_assoc PF08370.11 OQR85310.1 - 0.074 12.8 0.2 0.074 12.8 0.2 4.3 4 1 1 5 5 5 0 Plant PDR ABC transporter associated Pkinase PF00069.25 OQR85313.1 - 6.8e-54 183.0 0.0 9.5e-54 182.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQR85313.1 - 2.2e-50 171.4 0.0 3e-50 170.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase LRR_8 PF13855.6 OQR85313.1 - 3.8e-12 45.8 5.1 1.5e-05 24.6 0.2 3.2 1 1 2 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 OQR85313.1 - 2e-10 40.7 11.3 0.00014 22.2 0.2 4.3 2 2 2 4 4 4 3 Leucine Rich repeats (2 copies) Pkinase_fungal PF17667.1 OQR85313.1 - 4.7e-05 22.3 0.0 8.2e-05 21.6 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase LRR_1 PF00560.33 OQR85313.1 - 0.0043 17.4 4.4 41 5.3 0.0 5.1 5 0 0 5 5 5 0 Leucine Rich Repeat Pentapeptide_4 PF13599.6 OQR85313.1 - 0.011 15.9 1.7 1 9.6 1.7 2.5 1 1 0 1 1 1 0 Pentapeptide repeats (9 copies) Kdo PF06293.14 OQR85313.1 - 0.012 15.0 0.0 0.022 14.1 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 OQR85313.1 - 0.18 11.4 0.0 1.8 8.2 0.0 2.1 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 LRR_6 PF13516.6 OQR85313.1 - 0.95 9.7 8.4 6.3 7.1 0.5 4.6 3 1 1 4 4 4 0 Leucine Rich repeat UMP1 PF05348.11 OQR85315.1 - 2.9e-23 82.3 0.1 3.2e-23 82.2 0.1 1.0 1 0 0 1 1 1 1 Proteasome maturation factor UMP1 Ank_4 PF13637.6 OQR85316.1 - 4.8e-06 27.0 0.1 6.8e-05 23.3 0.0 2.4 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 OQR85316.1 - 2.4e-05 24.8 0.4 0.00011 22.8 0.4 2.0 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OQR85316.1 - 4.5e-05 23.6 0.0 0.26 11.7 0.0 3.1 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQR85316.1 - 0.012 16.1 0.0 6 7.8 0.0 3.2 3 0 0 3 3 3 0 Ankyrin repeat DUF2514 PF10721.9 OQR85316.1 - 0.079 13.0 0.7 0.52 10.3 0.3 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF2514) Cutinase PF01083.22 OQR85324.1 - 4.4e-42 144.0 2.1 5.2e-42 143.8 2.1 1.0 1 0 0 1 1 1 1 Cutinase Lipase_3 PF01764.25 OQR85324.1 - 0.011 15.6 0.0 0.019 14.9 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) Pkinase PF00069.25 OQR85332.1 - 8.1e-77 258.1 0.0 9.6e-77 257.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQR85332.1 - 2.6e-33 115.4 0.0 3.3e-33 115.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 OQR85332.1 - 0.00045 19.3 0.0 0.0022 17.0 0.0 1.8 1 1 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 OQR85332.1 - 0.003 17.5 0.0 0.015 15.2 0.0 1.8 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 OQR85332.1 - 0.016 14.5 0.1 0.082 12.2 0.0 2.0 2 0 0 2 2 2 0 Kinase-like Kdo PF06293.14 OQR85332.1 - 0.088 12.2 0.0 0.17 11.2 0.0 1.6 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Chitin_synth_2 PF03142.15 OQR85333.1 - 2.2e-17 62.9 6.1 3.7e-14 52.3 0.7 2.2 1 1 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.6 OQR85333.1 - 1.3e-08 35.0 5.0 1.3e-08 35.0 5.0 2.5 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 OQR85333.1 - 0.00013 21.9 0.0 0.00022 21.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 OQR85333.1 - 0.12 11.9 0.0 6.3 6.3 0.0 2.2 2 0 0 2 2 2 0 Glycosyl transferase family 21 Ank_2 PF12796.7 OQR85335.1 - 1e-08 35.6 0.0 1.9e-08 34.8 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OQR85335.1 - 1.5e-07 31.5 0.4 4e-05 23.8 0.4 2.4 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQR85335.1 - 3.3e-07 30.1 0.2 0.00098 19.4 0.1 3.2 3 0 0 3 3 3 1 Ankyrin repeat Ank_4 PF13637.6 OQR85335.1 - 8.7e-06 26.2 0.3 3.8e-05 24.2 0.2 1.9 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 OQR85335.1 - 8.7e-05 22.8 1.8 0.0025 18.2 0.7 2.7 2 1 1 3 3 3 1 Ankyrin repeat Pkinase_Tyr PF07714.17 OQR85335.1 - 0.0067 15.7 0.0 0.013 14.8 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OQR85335.1 - 0.018 14.4 0.1 0.027 13.8 0.1 1.3 1 0 0 1 1 1 0 Protein kinase domain HA PF03457.14 OQR85345.1 - 4.2e-43 145.5 9.8 3.4e-11 43.3 0.2 5.1 4 1 1 5 5 5 5 Helicase associated domain Ehbp PF10622.9 OQR85345.1 - 0.086 12.9 1.6 4.4 7.4 0.0 3.5 4 1 1 5 5 5 0 Energy-converting hydrogenase B subunit P (EhbP) PH PF00169.29 OQR85347.1 - 6.6e-13 49.1 0.8 1.1e-12 48.4 0.8 1.3 1 0 0 1 1 1 1 PH domain PH_8 PF15409.6 OQR85347.1 - 0.0008 19.6 3.6 0.0052 17.0 3.6 2.1 1 1 0 1 1 1 1 Pleckstrin homology domain PH_11 PF15413.6 OQR85347.1 - 0.00094 19.6 2.3 0.0016 18.8 2.3 1.4 1 0 0 1 1 1 1 Pleckstrin homology domain PH_2 PF08458.10 OQR85347.1 - 0.13 12.7 1.3 0.26 11.7 0.8 1.9 2 1 0 2 2 2 0 Plant pleckstrin homology-like region PH PF00169.29 OQR85348.1 - 1.8e-14 54.1 0.4 4.5e-14 52.8 0.4 1.7 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 OQR85348.1 - 4.8e-09 36.6 1.3 1.2e-07 32.1 1.8 2.4 2 0 0 2 2 2 1 Pleckstrin homology domain PI3K_rbd PF00794.18 OQR85348.1 - 2e-07 31.1 0.2 4.1e-07 30.1 0.2 1.5 1 0 0 1 1 1 1 PI3-kinase family, ras-binding domain PH_8 PF15409.6 OQR85348.1 - 0.0029 17.9 6.2 0.068 13.5 6.2 2.6 1 1 0 1 1 1 1 Pleckstrin homology domain Mcp5_PH PF12814.7 OQR85348.1 - 0.0038 17.3 0.3 0.0072 16.4 0.3 1.3 1 0 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology PH_9 PF15410.6 OQR85348.1 - 0.026 14.9 0.5 0.063 13.6 0.5 1.5 1 0 0 1 1 1 0 Pleckstrin homology domain Rab5-bind PF09311.11 OQR85348.1 - 0.11 11.8 0.2 0.17 11.2 0.2 1.2 1 0 0 1 1 1 0 Rabaptin-like protein NPR1_like_C PF12313.8 OQR85348.1 - 0.28 10.7 1.5 0.79 9.2 0.7 1.9 2 0 0 2 2 2 0 NPR1/NIM1 like defence protein C terminal ALIX_LYPXL_bnd PF13949.6 OQR85349.1 - 0.003 16.9 12.0 0.003 16.9 12.0 3.3 1 1 2 3 3 3 2 ALIX V-shaped domain binding to HIV DUF3772 PF12607.8 OQR85349.1 - 0.56 10.0 6.5 0.36 10.6 0.3 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3772) Herpes_ICP4_N PF03584.15 OQR85349.1 - 4.1 7.2 7.9 0.8 9.5 0.5 2.8 3 1 1 4 4 4 0 Herpesvirus ICP4-like protein N-terminal region DUF1382 PF07131.11 OQR85349.1 - 10 6.2 7.6 20 5.3 0.3 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1382) TPR_12 PF13424.6 OQR85351.1 - 4.3e-09 36.5 1.4 0.00072 19.8 1.4 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_10 PF13374.6 OQR85351.1 - 4e-06 26.5 3.1 0.028 14.3 0.0 4.7 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.17 OQR85351.1 - 0.00034 20.5 7.3 0.11 12.6 0.1 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.6 OQR85351.1 - 0.0004 20.4 2.5 3.9 7.9 0.1 4.4 4 0 0 4 4 4 1 Tetratricopeptide repeat GSCFA PF08885.11 OQR85351.1 - 0.027 14.1 0.0 0.27 10.8 0.0 2.0 1 1 1 2 2 2 0 GSCFA family TPR_6 PF13174.6 OQR85351.1 - 0.038 14.6 4.9 16 6.4 1.1 4.7 5 1 1 6 6 6 0 Tetratricopeptide repeat TPR_1 PF00515.28 OQR85351.1 - 0.066 13.1 3.1 6 6.9 0.0 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.6 OQR85351.1 - 0.085 12.9 1.8 2.9 8.1 0.0 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.6 OQR85351.1 - 0.25 12.3 7.9 17 6.5 0.6 4.9 3 1 2 5 5 5 0 Tetratricopeptide repeat TPR_16 PF13432.6 OQR85351.1 - 0.25 12.0 6.9 0.12 13.0 2.4 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat DAG_kinase_N PF14513.6 OQR85361.1 - 7.5 6.7 9.2 2.7 8.2 4.8 2.2 2 0 0 2 2 2 0 Diacylglycerol kinase N-terminus WD40 PF00400.32 OQR85362.1 - 1.2e-11 44.9 13.6 1.4e-05 25.7 0.1 5.1 6 1 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OQR85362.1 - 0.00037 20.7 0.1 0.0023 18.2 0.0 2.3 2 1 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 OQR85362.1 - 0.0018 17.0 4.6 0.018 13.7 0.3 2.2 2 0 0 2 2 2 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 OQR85362.1 - 0.034 12.9 0.1 0.072 11.8 0.0 1.6 1 1 0 1 1 1 0 Nup133 N terminal like Clathrin PF00637.20 OQR85363.1 - 1.6e-15 57.2 7.5 1.6e-14 53.9 1.5 3.2 3 0 0 3 3 3 1 Region in Clathrin and VPS zf-rbx1 PF12678.7 OQR85363.1 - 0.00016 21.9 0.7 0.00045 20.4 0.7 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger domain Vps39_2 PF10367.9 OQR85363.1 - 0.00054 20.4 1.6 0.0032 17.9 0.2 2.6 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 2 TPR_15 PF13429.6 OQR85363.1 - 0.004 16.4 0.0 0.08 12.1 0.0 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat zf-RING_2 PF13639.6 OQR85363.1 - 0.008 16.5 4.3 0.037 14.4 4.3 2.2 1 1 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 OQR85363.1 - 0.035 14.1 2.0 0.085 12.9 2.0 1.6 1 0 0 1 1 1 0 RING-type zinc-finger WD40 PF00400.32 OQR85363.1 - 0.042 14.7 2.2 0.18 12.7 0.1 3.2 4 0 0 4 4 4 0 WD domain, G-beta repeat zf-RING_5 PF14634.6 OQR85363.1 - 0.073 13.0 4.5 0.17 11.8 4.5 1.7 1 0 0 1 1 1 0 zinc-RING finger domain DUF2480 PF10652.9 OQR85363.1 - 0.13 12.1 1.0 0.5 10.3 1.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2480) zf-RING_11 PF17123.5 OQR85363.1 - 0.37 10.6 8.5 8.3 6.3 8.5 2.7 1 1 0 1 1 1 0 RING-like zinc finger zf-C3HC4_2 PF13923.6 OQR85363.1 - 0.61 10.0 3.9 7.4 6.5 1.0 2.8 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 OQR85363.1 - 0.79 9.6 4.7 2.2 8.2 4.7 1.9 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) TCTP PF00838.17 OQR85364.1 - 1.2e-16 61.6 0.4 1.3e-16 61.4 0.4 1.0 1 0 0 1 1 1 1 Translationally controlled tumour protein DUF2339 PF10101.9 OQR85365.1 - 0.61 8.6 22.7 7.3 5.0 21.8 1.9 1 1 1 2 2 2 0 Predicted membrane protein (DUF2339) Pkinase PF00069.25 OQR85366.1 - 3.9e-58 196.9 0.1 4.4e-58 196.7 0.1 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQR85366.1 - 1.6e-39 135.8 0.1 1.9e-39 135.5 0.1 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OQR85366.1 - 1.2e-06 27.6 0.0 3e-06 26.3 0.0 1.6 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 OQR85366.1 - 1.3e-05 24.6 0.0 0.00013 21.4 0.0 2.0 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 OQR85366.1 - 0.00029 20.9 0.0 0.28 11.1 0.0 2.1 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 OQR85366.1 - 0.0017 17.7 0.3 0.0041 16.5 0.3 1.6 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 OQR85366.1 - 0.063 12.9 0.1 0.08 12.5 0.1 1.2 1 0 0 1 1 1 0 RIO1 family Haspin_kinase PF12330.8 OQR85366.1 - 0.091 11.7 0.5 0.17 10.8 0.5 1.6 1 1 0 1 1 1 0 Haspin like kinase domain CBFD_NFYB_HMF PF00808.23 OQR85382.1 - 3.3e-26 91.3 0.1 4.4e-26 90.9 0.1 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 OQR85382.1 - 0.001 19.4 0.0 0.0017 18.7 0.0 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 OQR85382.1 - 0.0047 17.0 0.0 0.0057 16.8 0.0 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold Bromo_TP PF07524.13 OQR85382.1 - 0.013 15.5 0.0 0.026 14.5 0.0 1.5 1 1 0 1 1 1 0 Bromodomain associated TFIID_20kDa PF03847.13 OQR85382.1 - 0.028 14.9 0.5 0.76 10.3 0.1 2.2 2 0 0 2 2 2 0 Transcription initiation factor TFIID subunit A TFIID-18kDa PF02269.16 OQR85382.1 - 0.048 13.7 0.0 0.061 13.4 0.0 1.3 1 0 0 1 1 1 0 Transcription initiation factor IID, 18kD subunit DUF4286 PF14114.6 OQR85383.1 - 4.7e-10 39.8 0.1 6.5e-10 39.4 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4286) DUF2807 PF10988.8 OQR85384.1 - 0.0083 15.9 0.0 0.021 14.6 0.0 1.9 1 1 0 1 1 1 1 Putative auto-transporter adhesin, head GIN domain DUF4097 PF13349.6 OQR85384.1 - 0.03 13.7 0.1 0.067 12.5 0.1 1.5 1 1 0 1 1 1 0 Putative adhesin ABC_membrane PF00664.23 OQR85388.1 - 1e-19 71.3 16.6 1.3e-19 70.9 16.6 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 OQR85388.1 - 4e-07 30.6 0.3 9.5e-07 29.4 0.3 1.7 1 0 0 1 1 1 1 ABC transporter PduV-EutP PF10662.9 OQR85388.1 - 0.0093 15.7 0.1 0.49 10.1 0.0 3.1 3 0 0 3 3 3 1 Ethanolamine utilisation - propanediol utilisation RsgA_GTPase PF03193.16 OQR85388.1 - 0.011 15.6 1.4 0.03 14.2 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase ERp29 PF07749.12 OQR85388.1 - 0.033 15.1 0.1 0.079 13.9 0.1 1.6 1 0 0 1 1 1 0 Endoplasmic reticulum protein ERp29, C-terminal domain Dynamin_N PF00350.23 OQR85388.1 - 0.095 12.7 0.6 0.2 11.7 0.2 1.7 2 0 0 2 2 2 0 Dynamin family MMR_HSR1 PF01926.23 OQR85388.1 - 0.12 12.4 0.1 0.31 11.1 0.1 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase LSM PF01423.22 OQR85411.1 - 4.3e-11 42.3 0.0 5.3e-11 42.0 0.0 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 OQR85411.1 - 0.048 13.8 0.0 0.065 13.4 0.0 1.2 1 0 0 1 1 1 0 Ataxin 2 SM domain V_ATPase_I PF01496.19 OQR85412.1 - 0.002 16.1 18.5 0.0026 15.8 18.5 1.2 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family SOBP PF15279.6 OQR85412.1 - 0.19 12.3 34.3 0.29 11.7 34.3 1.4 1 0 0 1 1 1 0 Sine oculis-binding protein LAP1C PF05609.12 OQR85412.1 - 0.41 9.7 24.3 0.61 9.1 24.3 1.3 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) DUF572 PF04502.13 OQR85412.1 - 0.7 9.4 25.8 1.1 8.9 25.8 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) Zip PF02535.22 OQR85412.1 - 0.77 8.9 6.8 1.1 8.4 6.8 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter EIF4E-T PF10477.9 OQR85412.1 - 1.2 7.9 34.5 1.6 7.5 34.5 1.3 1 0 0 1 1 1 0 Nucleocytoplasmic shuttling protein for mRNA cap-binding EIF4E Nop53 PF07767.11 OQR85412.1 - 1.9 7.8 36.7 2.6 7.3 36.7 1.1 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) HCO3_cotransp PF00955.21 OQR85412.1 - 2.8 6.7 6.4 3.5 6.4 6.4 1.3 1 0 0 1 1 1 0 HCO3- transporter family CAF1 PF04857.20 OQR85412.1 - 3.3 6.8 17.5 2.5 7.2 16.0 1.5 1 1 0 1 1 1 0 CAF1 family ribonuclease LMBR1 PF04791.16 OQR85412.1 - 5.6 5.7 14.2 7.1 5.4 14.2 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein EMP24_GP25L PF01105.24 OQR85413.1 - 1.1e-27 97.1 0.2 1.3e-27 96.9 0.2 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD DUF667 PF05018.13 OQR85414.1 - 9.2e-30 103.7 0.3 1.6e-29 103.0 0.3 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF667) cNMP_binding PF00027.29 OQR85417.1 - 0.00038 20.5 0.0 0.00061 19.8 0.0 1.4 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Exo_endo_phos PF03372.23 OQR85421.1 - 0.17 11.4 0.8 0.3 10.6 0.8 1.4 1 1 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family RUN PF02759.19 OQR85421.1 - 0.17 11.8 0.1 0.26 11.2 0.1 1.2 1 0 0 1 1 1 0 RUN domain Ank_2 PF12796.7 OQR85434.1 - 1.9e-50 169.4 5.4 5.7e-15 55.7 0.1 3.6 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQR85434.1 - 1.1e-31 108.8 1.2 9.2e-10 38.9 0.0 5.2 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank PF00023.30 OQR85434.1 - 7.5e-30 102.1 7.2 3.1e-07 30.5 0.2 5.1 5 0 0 5 5 5 5 Ankyrin repeat Ank_5 PF13857.6 OQR85434.1 - 3.5e-27 94.1 4.5 2.3e-09 37.3 0.2 4.3 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQR85434.1 - 1.2e-26 89.8 0.8 4.9e-05 23.4 0.0 5.4 5 1 0 5 5 5 5 Ankyrin repeat ABC_tran PF00005.27 OQR85435.1 - 8.8e-23 81.3 0.2 4.9e-13 49.8 0.0 2.9 3 1 0 3 3 3 2 ABC transporter AAA_21 PF13304.6 OQR85435.1 - 3e-06 27.3 0.3 0.058 13.2 0.1 2.4 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 OQR85435.1 - 0.00026 20.5 0.6 0.15 11.5 0.0 2.7 3 0 0 3 3 3 2 RecF/RecN/SMC N terminal domain ABC_tran_Xtn PF12848.7 OQR85435.1 - 0.00027 20.9 4.5 0.00055 19.9 4.5 1.4 1 0 0 1 1 1 1 ABC transporter AAA_28 PF13521.6 OQR85435.1 - 0.0013 19.0 0.0 0.0027 17.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 OQR85435.1 - 0.0026 17.5 0.0 0.0071 16.1 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.6 OQR85435.1 - 0.0042 17.5 0.1 0.011 16.2 0.0 1.7 2 0 0 2 2 2 1 AAA ATPase domain AAA_23 PF13476.6 OQR85435.1 - 0.0049 17.4 2.4 0.44 11.0 0.0 2.3 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 OQR85435.1 - 0.0052 16.7 0.0 0.012 15.5 0.0 1.6 1 0 0 1 1 1 1 RsgA GTPase TcpS PF17456.2 OQR85435.1 - 0.0061 16.6 0.3 0.011 15.8 0.3 1.3 1 0 0 1 1 1 1 Toxin-coregulated pilus protein S AAA_22 PF13401.6 OQR85435.1 - 0.0072 16.6 1.1 0.072 13.4 0.0 2.4 3 0 0 3 3 3 1 AAA domain AAA_30 PF13604.6 OQR85435.1 - 0.032 13.9 0.0 0.059 13.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 OQR85435.1 - 0.04 14.5 0.2 0.11 13.0 0.0 1.8 2 0 0 2 2 2 0 AAA domain DUF4337 PF14235.6 OQR85435.1 - 0.73 9.9 3.0 1.2 9.2 3.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) Acyltransferase PF01553.21 OQR85436.1 - 6e-08 32.4 0.0 2.3e-07 30.5 0.0 2.0 3 0 0 3 3 3 1 Acyltransferase DASH_Dad1 PF08649.10 OQR85436.1 - 0.11 12.7 0.1 0.43 10.8 0.0 1.9 2 0 0 2 2 2 0 DASH complex subunit Dad1 NUMOD1 PF07453.13 OQR85436.1 - 0.13 12.5 0.0 0.3 11.4 0.0 1.7 1 0 0 1 1 1 0 NUMOD1 domain TTL PF03133.15 OQR85444.1 - 4.4e-53 180.3 0.3 7.3e-53 179.6 0.3 1.4 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 OQR85444.1 - 2.4e-05 23.7 0.0 0.004 16.4 0.0 2.5 2 0 0 2 2 2 2 YheC/D like ATP-grasp ATP-grasp_3 PF02655.14 OQR85444.1 - 0.00046 20.3 0.2 1.3 9.1 0.0 2.7 3 0 0 3 3 3 2 ATP-grasp domain Syntaxin_2 PF14523.6 OQR85444.1 - 0.012 16.0 1.3 0.031 14.7 1.3 1.7 1 0 0 1 1 1 0 Syntaxin-like protein YgaB PF14182.6 OQR85444.1 - 0.58 10.6 8.4 0.42 11.0 0.6 3.3 3 0 0 3 3 3 0 YgaB-like protein MULE PF10551.9 OQR85445.1 - 1.1e-10 41.8 1.1 2.4e-10 40.7 0.5 1.7 2 0 0 2 2 2 1 MULE transposase domain Ank_4 PF13637.6 OQR85446.1 - 1.6e-08 34.9 1.2 8.8e-05 23.0 0.1 3.1 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 OQR85446.1 - 4.4e-06 27.2 0.1 1.9e-05 25.1 0.1 2.0 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OQR85446.1 - 4.6e-06 26.8 0.4 0.15 12.4 0.0 2.8 2 1 0 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQR85446.1 - 1.9e-05 24.7 0.0 1.2 9.9 0.0 3.4 3 0 0 3 3 3 2 Ankyrin repeat UPF0302 PF08864.10 OQR85493.1 - 0.05 13.7 0.0 0.19 11.8 0.0 1.9 2 0 0 2 2 2 0 UPF0302 domain Oxysterol_BP PF01237.18 OQR85498.1 - 1.2e-45 156.0 0.0 1.5e-35 122.8 0.0 2.2 1 1 1 2 2 2 2 Oxysterol-binding protein PH PF00169.29 OQR85498.1 - 1.3e-12 48.1 0.1 4.3e-12 46.5 0.0 2.0 2 0 0 2 2 2 1 PH domain START PF01852.19 OQR85498.1 - 6.3e-11 42.1 0.0 2.4e-09 36.9 0.0 2.8 2 1 0 2 2 2 1 START domain PH_11 PF15413.6 OQR85498.1 - 0.00032 21.1 0.3 0.00097 19.5 0.3 1.9 1 1 0 1 1 1 1 Pleckstrin homology domain PH_8 PF15409.6 OQR85498.1 - 0.007 16.6 0.0 0.016 15.5 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain ABC2_membrane PF01061.24 OQR85502.1 - 8.8e-41 139.6 29.0 8.8e-41 139.6 29.0 1.9 2 0 0 2 2 2 1 ABC-2 type transporter PDR_assoc PF08370.11 OQR85502.1 - 9.4e-07 28.5 1.5 9.4e-07 28.5 1.5 2.6 2 0 0 2 2 2 1 Plant PDR ABC transporter associated ABC_tran PF00005.27 OQR85502.1 - 0.00036 21.1 0.5 0.00068 20.2 0.5 1.5 1 0 0 1 1 1 1 ABC transporter AAA_29 PF13555.6 OQR85502.1 - 0.0035 17.0 0.3 0.0071 16.1 0.3 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC2_membrane_3 PF12698.7 OQR85502.1 - 0.011 14.9 32.1 0.035 13.2 32.1 1.8 1 1 0 1 1 1 0 ABC-2 family transporter protein RsgA_GTPase PF03193.16 OQR85502.1 - 0.02 14.8 0.2 0.032 14.1 0.2 1.3 1 0 0 1 1 1 0 RsgA GTPase AAA_23 PF13476.6 OQR85502.1 - 0.31 11.5 0.7 0.51 10.8 0.7 1.3 1 0 0 1 1 1 0 AAA domain ERGIC_N PF13850.6 OQR85502.1 - 4.5 7.7 9.2 13 6.2 0.0 3.0 3 0 0 3 3 3 0 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Peptidase_M56 PF05569.11 OQR85518.1 - 2.1 7.4 8.5 6.4 5.9 1.5 2.4 2 1 0 2 2 2 0 BlaR1 peptidase M56 DisA-linker PF10635.9 OQR85519.1 - 0.045 13.5 0.1 0.058 13.2 0.1 1.4 1 0 0 1 1 1 0 DisA bacterial checkpoint controller linker region DUF2817 PF10994.8 OQR85541.1 - 7.3e-75 252.5 0.7 8.6e-75 252.2 0.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2817) AstE_AspA PF04952.14 OQR85541.1 - 0.002 17.3 0.0 0.0036 16.4 0.0 1.3 1 0 0 1 1 1 1 Succinylglutamate desuccinylase / Aspartoacylase family DUF1838 PF08894.11 OQR85541.1 - 0.0071 16.1 0.4 0.012 15.3 0.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1838) Rossmann-like PF10727.9 OQR85541.1 - 0.13 12.1 0.0 0.24 11.3 0.0 1.4 1 0 0 1 1 1 0 Rossmann-like domain DAGAT PF03982.13 OQR85542.1 - 0.00035 19.6 0.0 0.00053 19.0 0.0 1.2 1 0 0 1 1 1 1 Diacylglycerol acyltransferase RhoGAP PF00620.27 OQR85544.1 - 7.5e-14 51.8 5.8 8.6e-11 41.9 1.6 2.8 2 0 0 2 2 2 2 RhoGAP domain AI-2E_transport PF01594.16 OQR85544.1 - 0.24 10.5 0.9 0.53 9.4 0.9 1.5 1 0 0 1 1 1 0 AI-2E family transporter DUF1765 PF08578.10 OQR85544.1 - 0.26 11.7 5.2 6.2 7.3 0.2 3.5 2 1 1 3 3 3 0 Protein of unknown function (DUF1765) DENN PF02141.21 OQR85545.1 - 3.4e-21 76.0 3.8 7.8e-21 74.9 3.8 1.6 1 1 0 1 1 1 1 DENN (AEX-3) domain CNTF PF01110.17 OQR85545.1 - 0.16 11.3 0.1 0.26 10.6 0.1 1.4 1 1 0 1 1 1 0 Ciliary neurotrophic factor BT1 PF03092.16 OQR85548.1 - 6.5e-09 34.5 16.7 4.6e-08 31.7 2.1 3.1 2 1 1 3 3 3 2 BT1 family PUCC PF03209.15 OQR85548.1 - 0.0022 17.1 0.7 0.0022 17.1 0.7 2.6 3 0 0 3 3 3 1 PUCC protein E1-E2_ATPase PF00122.20 OQR85548.1 - 5 6.6 6.0 0.51 9.8 0.9 2.0 2 0 0 2 2 2 0 E1-E2 ATPase GIDE PF12483.8 OQR85549.1 - 0.097 12.1 0.0 0.17 11.3 0.0 1.4 1 0 0 1 1 1 0 E3 Ubiquitin ligase ABC_membrane PF00664.23 OQR85556.1 - 3.9e-21 75.9 18.8 6.2e-21 75.3 18.8 1.3 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 OQR85556.1 - 1.3e-14 54.9 0.0 3.2e-14 53.6 0.0 1.7 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 OQR85556.1 - 3.6e-06 26.6 0.8 0.0045 16.4 0.2 2.3 1 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 OQR85556.1 - 0.00051 19.9 0.0 0.033 14.0 0.0 2.3 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system Dynamin_N PF00350.23 OQR85556.1 - 0.0012 18.9 0.0 0.0021 18.1 0.0 1.4 1 0 0 1 1 1 1 Dynamin family AAA_29 PF13555.6 OQR85556.1 - 0.0041 16.8 0.5 0.0095 15.7 0.1 1.8 2 0 0 2 2 1 1 P-loop containing region of AAA domain Zeta_toxin PF06414.12 OQR85556.1 - 0.0041 16.4 0.0 0.0077 15.5 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin AAA_16 PF13191.6 OQR85556.1 - 0.0076 16.6 0.0 0.023 15.1 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain AAA_23 PF13476.6 OQR85556.1 - 0.0088 16.6 0.0 0.016 15.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 OQR85556.1 - 0.013 15.4 0.1 0.028 14.3 0.1 1.5 1 0 0 1 1 1 0 RsgA GTPase MMR_HSR1 PF01926.23 OQR85556.1 - 0.015 15.4 0.0 0.049 13.7 0.0 1.8 1 0 0 1 1 1 0 50S ribosome-binding GTPase FtsK_SpoIIIE PF01580.18 OQR85556.1 - 0.072 12.4 0.3 0.14 11.5 0.3 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family cobW PF02492.19 OQR85556.1 - 0.086 12.4 0.2 0.21 11.2 0.1 1.7 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_15 PF13175.6 OQR85556.1 - 0.096 12.4 0.2 0.16 11.6 0.2 1.3 1 0 0 1 1 1 0 AAA ATPase domain DUF815 PF05673.13 OQR85556.1 - 0.096 11.8 0.1 0.21 10.7 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) IML1 PF12257.8 OQR85563.1 - 0.055 12.6 0.2 0.098 11.8 0.2 1.5 1 0 0 1 1 1 0 Vacuolar membrane-associated protein Iml1 Abhydrolase_1 PF00561.20 OQR85568.1 - 5.6e-19 68.8 0.1 9e-19 68.1 0.1 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 OQR85568.1 - 1.2e-08 35.9 0.0 1.4e-08 35.6 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 OQR85568.1 - 8e-07 28.6 0.0 1e-06 28.2 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Esterase PF00756.20 OQR85568.1 - 0.0018 18.0 0.5 0.0034 17.1 0.3 1.4 1 1 0 1 1 1 1 Putative esterase PGAP1 PF07819.13 OQR85568.1 - 0.0065 16.2 0.0 0.011 15.5 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein Thioesterase PF00975.20 OQR85568.1 - 0.041 14.0 0.3 0.089 12.9 0.2 1.5 1 1 0 1 1 1 0 Thioesterase domain Ndr PF03096.14 OQR85568.1 - 0.068 11.9 0.1 0.12 11.0 0.0 1.5 2 0 0 2 2 2 0 Ndr family F420_oxidored PF03807.17 OQR85570.1 - 1.7e-09 38.1 0.0 2.6e-09 37.5 0.0 1.3 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.20 OQR85570.1 - 0.064 13.3 0.0 0.12 12.4 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Str_synth PF03088.16 OQR85613.1 - 1e-16 60.8 0.0 3.2e-16 59.2 0.0 1.8 2 0 0 2 2 2 1 Strictosidine synthase SGL PF08450.12 OQR85613.1 - 1e-09 38.3 0.0 2.1e-09 37.4 0.0 1.4 2 0 0 2 2 2 1 SMP-30/Gluconolactonase/LRE-like region Arylesterase PF01731.20 OQR85613.1 - 0.04 14.1 0.0 0.094 12.9 0.0 1.7 1 0 0 1 1 1 0 Arylesterase Spore_GerQ PF09671.10 OQR85613.1 - 0.2 11.7 0.0 0.43 10.6 0.0 1.5 1 0 0 1 1 1 0 Spore coat protein (Spore_GerQ) Exotox-A_cataly PF09009.10 OQR85614.1 - 1.1 9.0 11.3 7.5 6.3 0.3 3.7 2 2 1 3 3 3 0 Exotoxin A catalytic ABC_tran PF00005.27 OQR85633.1 - 2.7e-34 118.6 0.0 4.1e-34 118.0 0.0 1.3 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 OQR85633.1 - 4.3e-07 29.6 0.2 1.6e-05 24.5 0.0 2.2 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA PF00004.29 OQR85633.1 - 0.00033 21.1 0.0 0.055 13.9 0.0 2.2 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 OQR85633.1 - 0.00096 19.4 0.2 0.0098 16.2 0.2 2.2 1 1 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 OQR85633.1 - 0.0024 17.8 0.0 0.0045 16.9 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_16 PF13191.6 OQR85633.1 - 0.011 16.2 0.1 0.022 15.2 0.1 1.5 1 1 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.6 OQR85633.1 - 0.018 14.8 0.0 0.042 13.6 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_30 PF13604.6 OQR85633.1 - 0.037 13.7 0.0 0.16 11.7 0.0 1.8 2 0 0 2 2 2 0 AAA domain APS_kinase PF01583.20 OQR85633.1 - 0.04 13.8 0.0 0.1 12.5 0.0 1.7 1 0 0 1 1 1 0 Adenylylsulphate kinase SbcCD_C PF13558.6 OQR85633.1 - 0.048 13.9 0.3 0.84 9.9 0.3 2.4 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_15 PF13175.6 OQR85633.1 - 0.061 13.0 0.0 0.11 12.2 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain ABC_ATPase PF09818.9 OQR85633.1 - 0.062 12.1 0.1 0.14 10.9 0.0 1.7 2 0 0 2 2 2 0 Predicted ATPase of the ABC class AAA_21 PF13304.6 OQR85633.1 - 0.1 12.4 0.1 3.1 7.5 0.0 2.1 1 1 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system DEAD PF00270.29 OQR85633.1 - 0.14 11.9 0.0 0.61 9.8 0.0 1.8 1 1 0 1 1 1 0 DEAD/DEAH box helicase IstB_IS21 PF01695.17 OQR85633.1 - 0.15 11.8 0.0 1 9.1 0.0 2.1 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_7 PF12775.7 OQR85633.1 - 0.15 11.6 0.0 0.28 10.7 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_25 PF13481.6 OQR85633.1 - 0.16 11.5 0.0 4.3 6.9 0.0 2.1 2 0 0 2 2 2 0 AAA domain Rad17 PF03215.15 OQR85633.1 - 0.17 11.8 0.0 0.65 9.9 0.0 1.8 2 0 0 2 2 2 0 Rad17 P-loop domain Syntaxin-18_N PF10496.9 OQR85634.1 - 0.019 15.2 0.6 0.021 15.0 0.6 1.1 1 0 0 1 1 1 0 SNARE-complex protein Syntaxin-18 N-terminus DALR_2 PF09190.11 OQR85634.1 - 0.13 12.7 0.2 0.16 12.5 0.2 1.4 1 1 0 1 1 1 0 DALR domain Gln_deamidase_2 PF18626.1 OQR85647.1 - 0.12 12.7 0.1 0.13 12.5 0.1 1.1 1 0 0 1 1 1 0 Glutaminase 5_nucleotid_C PF02872.18 OQR85649.1 - 4.2e-10 40.1 0.1 5.9e-10 39.6 0.1 1.1 1 0 0 1 1 1 1 5'-nucleotidase, C-terminal domain SAM_adeno_trans PF01887.16 OQR85649.1 - 0.063 12.7 0.0 0.075 12.5 0.0 1.2 1 0 0 1 1 1 0 S-adenosyl-l-methionine hydroxide adenosyltransferase Glyco_hydro_47 PF01532.20 OQR85650.1 - 1.3e-123 413.3 0.0 2e-123 412.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Ank_2 PF12796.7 OQR85654.1 - 1.4e-81 269.1 12.2 3.9e-22 78.6 0.8 6.2 1 1 5 6 6 6 6 Ankyrin repeats (3 copies) Ank PF00023.30 OQR85654.1 - 1.3e-69 227.8 29.3 3.1e-08 33.7 0.1 11.3 10 1 1 11 11 11 11 Ankyrin repeat Ank_3 PF13606.6 OQR85654.1 - 5.1e-62 198.5 10.8 1.6e-05 24.9 0.1 11.3 11 0 0 11 11 11 11 Ankyrin repeat Ank_4 PF13637.6 OQR85654.1 - 6.1e-57 189.3 22.5 4.7e-11 43.0 0.1 8.2 2 2 7 9 9 9 9 Ankyrin repeats (many copies) Ank_5 PF13857.6 OQR85654.1 - 1.9e-33 114.0 15.5 1.2e-07 31.9 0.1 8.6 3 2 6 9 9 9 9 Ankyrin repeats (many copies) Pkinase_Tyr PF07714.17 OQR85654.1 - 2.2e-31 109.1 0.0 3e-31 108.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OQR85654.1 - 1.1e-26 93.8 0.0 1.7e-26 93.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Imm_superinfect PF14373.6 OQR85654.1 - 8.2e-05 22.5 0.6 4.1 7.4 0.0 6.6 8 0 0 8 8 8 1 Superinfection immunity protein DUF4205 PF13898.6 OQR85654.1 - 0.0075 15.2 1.5 0.84 8.5 0.1 2.8 2 1 0 3 3 3 2 Domain of unknown function (DUF4205) Arg_repressor PF01316.21 OQR85654.1 - 0.011 15.5 0.3 40 4.1 0.0 5.6 7 0 0 7 7 7 0 Arginine repressor, DNA binding domain DUF2170 PF09938.9 OQR85654.1 - 0.12 12.1 0.1 52 3.5 0.0 3.6 2 2 2 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2170) CPP1-like PF11833.8 OQR85655.1 - 0.025 14.2 0.1 0.035 13.7 0.1 1.2 1 0 0 1 1 1 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like Evr1_Alr PF04777.13 OQR85661.1 - 1e-25 90.1 1.5 1.4e-25 89.7 1.5 1.2 1 0 0 1 1 1 1 Erv1 / Alr family DUF1743 PF08489.11 OQR85661.1 - 0.044 13.8 0.0 0.058 13.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1743) CAF1 PF04857.20 OQR85662.1 - 1.1e-85 287.7 1.5 1.3e-85 287.4 1.5 1.1 1 0 0 1 1 1 1 CAF1 family ribonuclease DNA_pol_A_exo1 PF01612.20 OQR85662.1 - 0.022 14.4 0.1 1.2 8.8 0.0 2.4 2 0 0 2 2 2 0 3'-5' exonuclease DUF1664 PF07889.12 OQR85662.1 - 0.2 11.7 0.8 1.4 9.0 0.0 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) Fungal_TACC PF12709.7 OQR85662.1 - 0.32 11.5 2.2 0.93 10.0 0.1 2.6 2 0 0 2 2 2 0 Fungal Transforming acidic coiled-coil (TACC) proteins Glyco_hydro_14 PF01373.17 OQR85664.1 - 5.4e-92 308.8 4.6 6.2e-92 308.6 4.6 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 14 Ricin_B_lectin PF00652.22 OQR85668.1 - 7e-10 39.2 3.4 1.2e-09 38.4 3.4 1.4 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain MULE PF10551.9 OQR85671.1 - 3.6e-08 33.7 0.2 3.6e-06 27.3 0.1 2.5 2 0 0 2 2 2 1 MULE transposase domain zf-CCHC_2 PF13696.6 OQR85671.1 - 1.6e-05 24.6 2.3 3.9e-05 23.4 2.3 1.7 1 0 0 1 1 1 1 Zinc knuckle SWIM PF04434.17 OQR85671.1 - 0.0064 16.1 1.2 0.0064 16.1 1.2 3.4 3 1 0 3 3 3 1 SWIM zinc finger DnaJ_CXXCXGXG PF00684.19 OQR85671.1 - 0.79 10.1 5.5 1.2 9.5 0.4 3.3 4 0 0 4 4 4 0 DnaJ central domain Glyco_hydro_3 PF00933.21 OQR85674.1 - 4.7e-59 200.4 0.0 6.6e-59 199.9 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.22 OQR85674.1 - 2.4e-19 70.1 0.0 3.8e-19 69.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain AAA_6 PF12774.7 OQR85677.1 - 7.8e-147 488.5 0.0 3.1e-145 483.2 0.0 2.6 3 0 0 3 3 3 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 OQR85677.1 - 1.6e-111 373.2 10.5 2.8e-111 372.5 10.5 1.4 1 0 0 1 1 1 1 Dynein heavy chain, N-terminal region 2 AAA_7 PF12775.7 OQR85677.1 - 9.4e-85 282.7 0.1 2.7e-79 264.9 0.0 3.5 3 0 0 3 3 3 2 P-loop containing dynein motor region Dynein_AAA_lid PF17852.1 OQR85677.1 - 1.8e-30 105.6 0.0 5.2e-30 104.2 0.0 1.9 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_5 PF07728.14 OQR85677.1 - 3.1e-22 79.0 0.0 1.4e-06 28.3 0.0 4.9 3 1 0 3 3 3 3 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 OQR85677.1 - 1.8e-09 38.0 0.1 0.1 12.9 0.0 4.5 4 0 0 4 4 4 2 AAA domain AAA_lid_1 PF17857.1 OQR85677.1 - 2.1e-09 37.5 0.0 6.1e-09 36.0 0.0 1.9 1 0 0 1 1 1 1 AAA+ lid domain AAA PF00004.29 OQR85677.1 - 2.1e-07 31.4 0.4 0.47 10.9 0.0 4.7 4 0 0 4 4 4 1 ATPase family associated with various cellular activities (AAA) T2SSE PF00437.20 OQR85677.1 - 1.3e-05 24.4 0.8 0.11 11.6 0.1 2.8 3 0 0 3 3 3 2 Type II/IV secretion system protein AAA_16 PF13191.6 OQR85677.1 - 1.4e-05 25.6 0.1 2 8.8 0.0 3.8 3 0 0 3 3 3 1 AAA ATPase domain AAA_30 PF13604.6 OQR85677.1 - 0.0001 22.1 1.8 1.3 8.7 0.1 3.5 3 0 0 3 3 3 1 AAA domain RNA_helicase PF00910.22 OQR85677.1 - 0.00016 22.1 0.8 6.4 7.2 0.0 4.2 4 0 0 4 4 3 0 RNA helicase Sigma54_activat PF00158.26 OQR85677.1 - 0.00018 21.3 1.1 1.5 8.5 0.0 3.3 3 0 0 3 3 3 2 Sigma-54 interaction domain DUF853 PF05872.12 OQR85677.1 - 0.00035 19.3 1.8 0.32 9.5 0.1 3.0 3 0 0 3 3 3 2 Bacterial protein of unknown function (DUF853) Mg_chelatase PF01078.21 OQR85677.1 - 0.0005 19.5 0.6 1.1 8.6 0.0 3.6 4 0 0 4 4 4 1 Magnesium chelatase, subunit ChlI FtsK_SpoIIIE PF01580.18 OQR85677.1 - 0.00083 18.8 0.2 0.32 10.3 0.0 2.6 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_19 PF13245.6 OQR85677.1 - 0.0014 19.0 1.2 34 4.7 0.0 4.8 5 0 0 5 5 4 0 AAA domain AAA_25 PF13481.6 OQR85677.1 - 0.0087 15.7 0.4 4.1 6.9 0.0 3.1 3 0 0 3 3 3 1 AAA domain AAA_29 PF13555.6 OQR85677.1 - 0.012 15.3 1.3 5.4 6.8 0.0 3.4 3 0 0 3 3 3 0 P-loop containing region of AAA domain DUF2451 PF10474.9 OQR85677.1 - 0.017 14.9 0.4 1.1 9.0 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function C-terminus (DUF2451) DEAD PF00270.29 OQR85677.1 - 0.026 14.3 0.0 3.7 7.3 0.0 2.6 2 0 0 2 2 2 0 DEAD/DEAH box helicase TsaE PF02367.17 OQR85677.1 - 0.035 14.1 1.7 19 5.3 0.1 4.0 4 0 0 4 4 4 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE DUF815 PF05673.13 OQR85677.1 - 0.037 13.2 0.5 0.71 9.0 0.1 2.8 3 1 0 3 3 3 0 Protein of unknown function (DUF815) AAA_33 PF13671.6 OQR85677.1 - 0.045 13.9 0.0 2.7 8.2 0.0 2.9 2 0 0 2 2 2 0 AAA domain SKA2 PF16740.5 OQR85677.1 - 0.096 12.5 0.1 0.4 10.5 0.1 2.1 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 2 TrwB_AAD_bind PF10412.9 OQR85677.1 - 0.12 11.3 3.1 7.5 5.3 0.3 3.3 3 0 0 3 3 3 0 Type IV secretion-system coupling protein DNA-binding domain SRP54 PF00448.22 OQR85677.1 - 0.12 12.0 0.4 1.2 8.7 0.1 2.5 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_18 PF13238.6 OQR85677.1 - 0.12 12.9 8.4 0.18 12.4 0.0 4.0 5 0 0 5 5 2 0 AAA domain NACHT PF05729.12 OQR85677.1 - 0.13 12.1 0.2 11 5.9 0.0 3.1 3 0 0 3 3 3 0 NACHT domain AAA_24 PF13479.6 OQR85677.1 - 0.15 11.7 0.8 5.2 6.7 0.0 3.2 3 0 0 3 3 3 0 AAA domain ResIII PF04851.15 OQR85677.1 - 0.17 11.8 1.0 2.6 8.0 0.0 3.0 3 0 0 3 3 3 0 Type III restriction enzyme, res subunit DUF2075 PF09848.9 OQR85677.1 - 0.49 9.6 2.9 5.7 6.1 0.0 2.6 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2075) ABC_tran PF00005.27 OQR85677.1 - 0.5 10.9 2.2 6.6 7.3 0.0 3.3 4 0 0 4 4 2 0 ABC transporter DUF87 PF01935.17 OQR85677.1 - 8.6 6.4 10.9 4.6 7.3 0.2 3.4 4 0 0 4 4 4 0 Helicase HerA, central domain Pkinase PF00069.25 OQR85679.1 - 1e-46 159.4 0.0 1.4e-46 159.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQR85679.1 - 1.6e-46 158.7 0.0 2.3e-46 158.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase TMEM154 PF15102.6 OQR85679.1 - 0.00049 20.0 0.4 0.00087 19.2 0.4 1.3 1 0 0 1 1 1 1 TMEM154 protein family DUF5305 PF17231.2 OQR85679.1 - 0.0014 18.1 0.3 0.0022 17.4 0.3 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF5305) Adeno_E3_CR2 PF02439.15 OQR85679.1 - 0.031 14.1 0.4 0.06 13.1 0.4 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 APH PF01636.23 OQR85679.1 - 0.15 12.0 0.0 0.3 11.0 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Peptidase_S10 PF00450.22 OQR85680.1 - 2.9e-96 323.4 0.0 3.3e-96 323.3 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Peptidase_S10 PF00450.22 OQR85681.1 - 4.4e-26 92.3 1.0 5e-26 92.1 1.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Ank_2 PF12796.7 OQR85689.1 - 2.9e-82 271.3 15.6 2.6e-13 50.3 0.2 7.0 2 2 6 8 8 8 8 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OQR85689.1 - 1.3e-58 188.0 8.2 0.00084 19.6 0.0 13.1 13 0 0 13 13 13 12 Ankyrin repeat Ank_4 PF13637.6 OQR85689.1 - 4.6e-58 192.9 3.0 3.1e-10 40.4 0.1 10.0 4 3 6 10 10 10 10 Ankyrin repeats (many copies) Ank_5 PF13857.6 OQR85689.1 - 1.1e-54 181.8 14.5 5.9e-09 36.0 0.0 11.0 4 2 7 11 11 11 11 Ankyrin repeats (many copies) Ank PF00023.30 OQR85689.1 - 7.7e-48 158.9 17.6 0.00027 21.2 0.1 13.2 14 0 0 14 14 14 12 Ankyrin repeat Ribosomal_S4e PF00900.20 OQR85689.1 - 0.022 14.7 0.0 23 5.0 0.0 3.7 3 2 1 4 4 4 0 Ribosomal family S4e VWA_3_C PF18571.1 OQR85689.1 - 0.028 14.3 0.0 41 4.1 0.0 4.6 5 0 0 5 5 5 0 von Willebrand factor type A C-terminal domain Nitro_FeMo-Co PF02579.17 OQR85689.1 - 0.17 12.2 0.4 36 4.8 0.0 3.5 4 1 0 4 4 4 0 Dinitrogenase iron-molybdenum cofactor DENN PF02141.21 OQR85694.1 - 1.5e-31 109.8 2.1 2.7e-31 109.0 2.1 1.5 1 0 0 1 1 1 1 DENN (AEX-3) domain RGS PF00615.19 OQR85694.1 - 1.7e-08 34.8 1.1 2.9e-08 34.0 1.1 1.4 1 0 0 1 1 1 1 Regulator of G protein signaling domain dDENN PF03455.19 OQR85694.1 - 0.051 13.6 0.0 0.14 12.2 0.0 1.8 1 0 0 1 1 1 0 dDENN domain Ank_2 PF12796.7 OQR85700.1 - 1.5e-41 140.9 0.0 8.8e-14 51.9 0.0 3.6 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OQR85700.1 - 2.9e-36 123.0 0.0 2e-07 31.1 0.0 4.5 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank PF00023.30 OQR85700.1 - 1.7e-33 113.5 0.0 1e-05 25.7 0.0 5.1 5 0 0 5 5 5 5 Ankyrin repeat Ank_4 PF13637.6 OQR85700.1 - 3.2e-33 113.7 0.0 1e-10 41.9 0.0 4.0 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQR85700.1 - 4.9e-33 109.4 0.0 6.5e-05 23.0 0.0 5.1 5 0 0 5 5 5 5 Ankyrin repeat Shigella_OspC PF06128.11 OQR85700.1 - 0.0015 18.3 0.1 0.99 9.1 0.0 3.5 1 1 3 4 4 4 1 Shigella flexneri OspC protein Ad_Cy_reg PF16701.5 OQR85700.1 - 0.0045 16.7 3.2 16 5.2 0.0 4.0 1 1 3 4 4 4 0 Adenylate cyclase regulatory domain UDPG_MGDP_dh_C PF03720.15 OQR85700.1 - 0.0073 16.7 0.3 12 6.3 0.1 3.8 1 1 1 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain Borealin PF10512.9 OQR85700.1 - 0.011 15.7 0.0 3.8 7.5 0.0 3.2 1 1 2 3 3 3 0 Cell division cycle-associated protein 8 INT_SG_DDX_CT_C PF15300.6 OQR85700.1 - 0.03 14.1 0.0 1.3 8.9 0.0 2.9 3 0 0 3 3 3 0 INTS6/SAGE1/DDX26B/CT45 C-terminus AbiJ_NTD3 PF18860.1 OQR85700.1 - 0.077 12.5 0.1 12 5.4 0.0 2.3 1 1 1 2 2 2 0 AbiJ N-terminal domain 3 Phage_C PF12025.8 OQR85700.1 - 0.083 12.7 0.3 40 4.2 0.0 3.7 4 0 0 4 4 4 0 Phage protein C DUF150 PF02576.17 OQR85700.1 - 0.21 12.0 5.5 67 4.0 0.1 4.5 4 1 0 4 4 4 0 RimP N-terminal domain CAP18_C PF12153.8 OQR85700.1 - 0.48 10.3 3.0 22 5.0 0.3 3.8 4 0 0 4 4 4 0 LPS binding domain of CAP18 (C terminal) ThiF PF00899.21 OQR85714.1 - 6.2e-17 61.8 0.2 1.2e-15 57.6 0.2 2.0 1 1 0 1 1 1 1 ThiF family cNMP_binding PF00027.29 OQR85715.1 - 6.3e-15 55.0 0.1 1.1e-14 54.3 0.1 1.4 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain STAS PF01740.21 OQR85715.1 - 3.3e-10 39.6 0.1 7e-10 38.6 0.1 1.5 1 0 0 1 1 1 1 STAS domain Sulfate_transp PF00916.20 OQR85715.1 - 5.8e-05 22.0 0.1 0.00011 21.1 0.1 1.5 1 0 0 1 1 1 1 Sulfate permease family STAS_2 PF13466.6 OQR85715.1 - 0.0012 19.1 0.0 0.0025 18.1 0.0 1.5 1 0 0 1 1 1 1 STAS domain OxoGdeHyase_C PF16870.5 OQR85715.1 - 0.03 14.0 0.0 0.048 13.3 0.0 1.2 1 0 0 1 1 1 0 2-oxoglutarate dehydrogenase C-terminal Baculo_PEP_C PF04513.12 OQR85716.1 - 0.035 14.2 0.3 0.04 14.0 0.3 1.1 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Rhodanese PF00581.20 OQR85718.1 - 7.6e-10 39.3 0.0 1e-09 38.9 0.0 1.1 1 0 0 1 1 1 1 Rhodanese-like domain Gly_reductase PF09338.11 OQR85718.1 - 0.017 13.6 0.0 0.018 13.4 0.0 1.0 1 0 0 1 1 1 0 Glycine/sarcosine/betaine reductase component B subunits LCCL PF03815.19 OQR85719.1 - 2.4 8.3 7.3 7.6 6.7 2.8 2.4 1 1 1 2 2 2 0 LCCL domain DUF726 PF05277.12 OQR85720.1 - 8.1e-19 67.7 0.0 1.3e-18 67.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF726) Lipase_3 PF01764.25 OQR85720.1 - 2e-06 27.7 0.0 4e-05 23.5 0.0 2.2 2 0 0 2 2 2 1 Lipase (class 3) DUF900 PF05990.12 OQR85720.1 - 0.0033 17.0 0.0 0.0096 15.5 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF900) DUF676 PF05057.14 OQR85720.1 - 0.01 15.4 0.1 0.022 14.3 0.0 1.6 2 0 0 2 2 2 0 Putative serine esterase (DUF676) Abhydrolase_1 PF00561.20 OQR85720.1 - 0.025 14.2 0.0 0.05 13.3 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 OQR85720.1 - 0.028 13.7 0.0 0.046 13.0 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Aconitase_B_N PF11791.8 OQR85720.1 - 0.035 14.2 0.0 0.068 13.2 0.0 1.5 1 0 0 1 1 1 0 Aconitate B N-terminal domain Abhydrolase_6 PF12697.7 OQR85720.1 - 0.044 14.4 0.1 0.13 12.9 0.0 1.6 1 1 0 2 2 2 0 Alpha/beta hydrolase family cNMP_binding PF00027.29 OQR85727.1 - 2.2e-16 59.7 0.0 1.3e-09 38.0 0.0 2.5 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain TPR_9 PF13371.6 OQR85727.1 - 0.044 13.9 0.0 0.088 13.0 0.0 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat MazG PF03819.17 OQR85727.1 - 0.072 13.3 0.0 12 6.2 0.0 3.3 2 1 1 3 3 3 0 MazG nucleotide pyrophosphohydrolase domain Sugar_tr PF00083.24 OQR85734.1 - 2.8e-21 75.9 6.7 3.2e-21 75.7 6.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OQR85734.1 - 5.7e-09 35.4 8.9 5.7e-09 35.4 8.9 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily ABC2_membrane_3 PF12698.7 OQR85734.1 - 0.0095 15.1 3.2 0.043 12.9 3.8 1.6 1 1 0 1 1 1 1 ABC-2 family transporter protein MFS_2 PF13347.6 OQR85734.1 - 0.014 14.0 0.9 0.014 14.0 0.9 1.4 2 0 0 2 2 2 0 MFS/sugar transport protein 7tm_3 PF00003.22 OQR85734.1 - 0.018 14.8 0.5 0.36 10.5 0.1 2.0 2 0 0 2 2 2 0 7 transmembrane sweet-taste receptor of 3 GCPR Ank_4 PF13637.6 OQR85737.1 - 1e-21 77.0 4.9 4.4e-09 36.7 0.0 3.6 3 0 0 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 OQR85737.1 - 1.7e-21 76.6 4.4 1.2e-06 29.0 0.5 3.6 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.30 OQR85737.1 - 3.3e-17 62.1 3.9 0.00093 19.5 0.7 5.8 5 0 0 5 5 5 5 Ankyrin repeat Ank_3 PF13606.6 OQR85737.1 - 1.4e-14 52.7 7.1 0.047 14.2 0.0 6.8 6 0 0 6 6 6 4 Ankyrin repeat Ank_5 PF13857.6 OQR85737.1 - 7.1e-14 51.7 5.0 3.2e-06 27.3 0.3 4.2 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Dimer_Tnp_hAT PF05699.14 OQR85738.1 - 0.01 15.6 0.0 0.021 14.6 0.0 1.7 1 1 0 1 1 1 0 hAT family C-terminal dimerisation region MatE PF01554.18 OQR85755.1 - 1e-20 74.0 23.3 7.4e-17 61.5 11.2 2.2 2 0 0 2 2 2 2 MatE Polysacc_synt_C PF14667.6 OQR85755.1 - 0.0041 17.2 15.5 0.0041 17.2 15.5 2.6 1 1 1 2 2 2 1 Polysaccharide biosynthesis C-terminal domain PsbN PF02468.15 OQR85755.1 - 0.11 12.3 0.9 0.79 9.6 0.9 2.5 1 0 0 1 1 1 0 Photosystem II reaction centre N protein (psbN) HTH_Tnp_Tc5 PF03221.16 OQR85758.1 - 7.2e-12 45.2 0.0 1e-11 44.6 0.0 1.3 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain MFS_1 PF07690.16 OQR85765.1 - 2.3e-10 39.9 22.4 2.8e-10 39.6 22.4 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 OQR85765.1 - 0.15 10.9 17.1 0.017 14.0 7.3 2.0 1 1 1 2 2 2 0 Sugar (and other) transporter Metallophos PF00149.28 OQR85770.1 - 1.3e-15 58.5 0.0 1.7e-15 58.1 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Pur_ac_phosph_N PF16656.5 OQR85770.1 - 3.5e-08 33.9 2.5 8.9e-08 32.6 2.5 1.7 1 0 0 1 1 1 1 Purple acid Phosphatase, N-terminal domain DUF365 PF04033.12 OQR85770.1 - 0.15 12.4 0.0 4.2 7.7 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF365) Ion_trans PF00520.31 OQR85771.1 - 1.3e-20 73.7 8.2 2.5e-20 72.7 8.2 1.5 1 0 0 1 1 1 1 Ion transport protein cNMP_binding PF00027.29 OQR85771.1 - 1.8e-18 66.4 0.0 3.6e-18 65.4 0.0 1.5 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Ion_trans_2 PF07885.16 OQR85771.1 - 1.3e-12 47.5 6.9 2.9e-12 46.4 6.9 1.6 1 0 0 1 1 1 1 Ion channel RasGAP_C PF03836.15 OQR85771.1 - 0.061 13.5 0.4 1.2 9.3 0.0 2.2 2 0 0 2 2 2 0 RasGAP C-terminus ABC_tran PF00005.27 OQR85778.1 - 3.4e-26 92.4 0.1 3e-12 47.2 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 OQR85778.1 - 2.2e-20 73.5 25.4 4.1e-18 66.0 15.8 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region AAA_16 PF13191.6 OQR85778.1 - 4.4e-05 23.9 0.0 0.021 15.2 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain MMR_HSR1 PF01926.23 OQR85778.1 - 0.00068 19.7 0.2 0.023 14.8 0.3 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 OQR85778.1 - 0.0024 17.8 0.0 0.56 10.1 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase AAA_22 PF13401.6 OQR85778.1 - 0.0055 17.0 0.4 0.98 9.7 0.1 2.4 2 0 0 2 2 2 1 AAA domain T2SSE PF00437.20 OQR85778.1 - 0.0062 15.6 0.0 0.15 11.1 0.0 2.2 2 0 0 2 2 2 1 Type II/IV secretion system protein IstB_IS21 PF01695.17 OQR85778.1 - 0.007 16.1 0.0 0.57 9.9 0.0 2.4 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_25 PF13481.6 OQR85778.1 - 0.0098 15.5 0.0 6 6.4 0.0 2.4 2 0 0 2 2 2 2 AAA domain TsaE PF02367.17 OQR85778.1 - 0.012 15.6 0.1 1.9 8.5 0.0 2.4 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE RNA_helicase PF00910.22 OQR85778.1 - 0.014 15.7 0.0 2.4 8.6 0.0 2.6 2 0 0 2 2 2 0 RNA helicase AAA_7 PF12775.7 OQR85778.1 - 0.027 14.0 0.1 8.9 5.8 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_29 PF13555.6 OQR85778.1 - 0.03 14.1 0.1 1.8 8.4 0.0 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain Zeta_toxin PF06414.12 OQR85778.1 - 0.076 12.3 0.1 2.5 7.3 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin PduV-EutP PF10662.9 OQR85778.1 - 0.11 12.3 0.2 23 4.7 0.0 2.7 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation ATP-synt_ab PF00006.25 OQR85778.1 - 0.13 11.9 0.0 12 5.5 0.0 2.2 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_23 PF13476.6 OQR85778.1 - 0.17 12.4 0.2 2 8.9 0.1 2.1 2 0 0 2 2 2 0 AAA domain cobW PF02492.19 OQR85778.1 - 0.17 11.5 0.3 13 5.3 0.0 3.3 4 0 0 4 4 4 0 CobW/HypB/UreG, nucleotide-binding domain NB-ARC PF00931.22 OQR85778.1 - 0.27 10.4 1.2 13 4.8 0.1 2.4 2 0 0 2 2 2 0 NB-ARC domain MSA-2c PF12238.8 OQR85782.1 - 0.77 9.7 10.6 1.5 8.8 10.4 1.5 2 0 0 2 2 2 0 Merozoite surface antigen 2c Med3 PF11593.8 OQR85782.1 - 0.94 8.6 0.0 0.94 8.6 0.0 2.2 2 0 0 2 2 2 0 Mediator complex subunit 3 fungal DDE_1 PF03184.19 OQR85796.1 - 6.7e-15 55.2 0.2 7.8e-15 55.0 0.2 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease RAMP PF04901.13 OQR85800.1 - 0.033 14.2 1.3 94 3.1 0.0 4.0 4 0 0 4 4 4 0 Receptor activity modifying family Ank_4 PF13637.6 OQR85821.1 - 3.7e-17 62.4 1.5 3.1e-09 37.2 0.1 2.0 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 OQR85821.1 - 1.5e-13 51.1 0.5 1.7e-13 50.9 0.5 1.0 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OQR85821.1 - 9.8e-13 47.1 0.6 3.2e-06 27.0 0.1 3.0 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.6 OQR85821.1 - 2.8e-12 46.6 0.9 5.8e-12 45.6 0.5 1.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 OQR85821.1 - 1.5e-08 34.7 1.7 0.0013 19.1 0.4 3.1 3 0 0 3 3 3 3 Ankyrin repeat DCP2 PF05026.13 OQR85827.1 - 0.057 13.7 0.5 0.54 10.6 0.1 3.0 2 0 0 2 2 2 0 Dcp2, box A domain HSP70 PF00012.20 OQR85839.1 - 3e-267 887.7 4.4 3.5e-267 887.5 4.4 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 OQR85839.1 - 2e-15 56.5 0.1 2.9e-14 52.6 0.0 2.0 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.16 OQR85839.1 - 0.002 17.9 0.0 0.0055 16.5 0.0 1.7 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain DDR PF08841.10 OQR85839.1 - 0.008 15.2 0.2 0.046 12.7 0.1 2.0 2 0 0 2 2 2 1 Diol dehydratase reactivase ATPase-like domain PilM_2 PF11104.8 OQR85839.1 - 0.055 12.5 0.0 4.1 6.3 0.0 2.3 2 0 0 2 2 2 0 Type IV pilus assembly protein PilM; MutS_III PF05192.18 OQR85839.1 - 0.33 11.1 2.5 13 5.9 1.3 2.4 2 0 0 2 2 2 0 MutS domain III Ank_2 PF12796.7 OQR85842.1 - 2.9e-179 582.2 59.2 1.5e-17 64.0 0.2 15.1 2 2 14 16 16 16 16 Ankyrin repeats (3 copies) Ank PF00023.30 OQR85842.1 - 1e-132 427.3 79.2 3.6e-06 27.2 0.1 27.0 26 1 1 27 27 27 26 Ankyrin repeat Ank_4 PF13637.6 OQR85842.1 - 1.3e-120 392.4 35.7 4.9e-09 36.6 0.0 21.5 5 5 18 24 24 24 24 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQR85842.1 - 1.3e-106 335.5 32.2 0.00014 22.0 0.0 26.6 26 1 1 27 27 27 24 Ankyrin repeat Ank_5 PF13857.6 OQR85842.1 - 3.3e-102 333.2 43.7 3.5e-10 39.9 0.0 17.4 9 5 9 18 18 18 18 Ankyrin repeats (many copies) PEGA PF08308.11 OQR85842.1 - 3.2e-06 26.9 2.5 47 4.0 0.0 9.3 10 0 0 10 10 10 0 PEGA domain GDPD_2 PF13653.6 OQR85842.1 - 7.6e-06 26.2 0.0 1.1e+02 3.5 0.0 8.3 9 0 0 9 9 9 0 Glycerophosphoryl diester phosphodiesterase family YfmQ PF10787.9 OQR85842.1 - 1.4e-05 24.9 0.0 40 4.0 0.0 7.0 4 2 2 7 7 7 0 Uncharacterised protein from bacillus cereus group GATase_7 PF13537.6 OQR85842.1 - 0.0033 17.3 0.0 26 4.7 0.0 7.2 11 1 1 12 12 12 0 Glutamine amidotransferase domain Tnp_P_element_C PF12596.8 OQR85842.1 - 0.21 12.1 2.5 71 4.0 0.0 4.5 4 0 0 4 4 4 0 87kDa Transposase Glyco_hydro_19 PF00182.19 OQR85872.1 - 6.3e-26 91.7 22.5 3.3e-13 50.1 0.9 4.0 2 1 2 4 4 4 3 Chitinase class I Chitin_bind_1 PF00187.19 OQR85872.1 - 3.4e-10 40.2 48.1 5.8e-06 26.7 17.5 3.0 3 0 0 3 3 3 2 Chitin recognition protein ABC_membrane PF00664.23 OQR85879.1 - 3.9e-29 102.2 13.4 5.4e-29 101.7 13.4 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 OQR85879.1 - 1.7e-07 31.8 0.1 3.9e-07 30.7 0.1 1.7 1 0 0 1 1 1 1 ABC transporter MMR_HSR1 PF01926.23 OQR85879.1 - 0.014 15.4 0.3 0.037 14.1 0.3 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase TauD PF02668.16 OQR85886.1 - 1.2e-25 90.8 0.3 1.6e-25 90.5 0.3 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family ADIP PF11559.8 OQR85888.1 - 0.075 13.1 2.3 0.29 11.2 1.8 1.9 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding XRCC4 PF06632.12 OQR85889.1 - 0.00049 19.1 9.1 0.00061 18.8 9.1 1.1 1 0 0 1 1 1 1 DNA double-strand break repair and V(D)J recombination protein XRCC4 DUF4201 PF13870.6 OQR85889.1 - 0.018 14.8 6.4 0.037 13.8 2.7 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) DUF4407 PF14362.6 OQR85889.1 - 0.34 10.2 9.4 0.46 9.8 9.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) TolA_bind_tri PF16331.5 OQR85889.1 - 0.87 9.7 5.8 0.71 10.0 3.4 2.1 2 1 0 2 2 2 0 TolA binding protein trimerisation BLOC1_2 PF10046.9 OQR85889.1 - 1 9.7 8.1 4.7 7.6 0.2 2.6 2 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DivIC PF04977.15 OQR85889.1 - 7.5 6.4 7.4 3.3 7.5 1.0 2.8 3 0 0 3 3 3 0 Septum formation initiator UPF0242 PF06785.11 OQR85889.1 - 8.1 6.5 11.2 5 7.2 9.5 1.5 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus CBM_1 PF00734.18 OQR85890.1 - 1.7e-14 53.4 25.3 3.3e-08 33.3 0.5 3.4 3 1 0 3 3 3 2 Fungal cellulose binding domain SH3_16 PF18348.1 OQR85890.1 - 0.11 12.3 1.1 0.25 11.2 1.1 1.5 1 0 0 1 1 1 0 Bacterial dipeptidyl-peptidase Sh3 domain Arf PF00025.21 OQR85894.1 - 8.5e-14 51.4 0.0 2.1e-13 50.1 0.0 1.6 1 1 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.20 OQR85894.1 - 7.6e-06 25.3 0.0 0.076 12.2 0.0 2.2 2 0 0 2 2 2 2 G-protein alpha subunit MMR_HSR1 PF01926.23 OQR85894.1 - 0.00024 21.1 0.0 0.00048 20.2 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 OQR85894.1 - 0.0042 16.6 0.0 0.0076 15.7 0.0 1.4 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 OQR85894.1 - 0.0055 16.3 0.0 0.0091 15.5 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 OQR85894.1 - 0.16 11.3 0.0 0.89 8.9 0.0 1.9 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region Ricin_B_lectin PF00652.22 OQR85899.1 - 3.6e-13 49.9 4.2 1.1e-06 29.0 0.9 3.2 1 1 2 3 3 3 3 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.6 OQR85899.1 - 0.00055 20.6 2.3 0.17 12.7 0.1 3.2 2 1 1 3 3 3 2 Ricin-type beta-trefoil lectin domain-like Tctex-1 PF03645.13 OQR85903.1 - 7.3e-05 22.9 0.0 8.7e-05 22.7 0.0 1.0 1 0 0 1 1 1 1 Tctex-1 family Cnd1 PF12717.7 OQR85904.1 - 2e-50 171.0 14.1 7.1e-50 169.2 0.2 5.1 5 0 0 5 5 5 2 non-SMC mitotic condensation complex subunit 1 ESCRT-II PF05871.12 OQR85904.1 - 1.1e-41 142.4 1.2 3.2e-41 140.9 1.2 1.9 1 0 0 1 1 1 1 ESCRT-II complex subunit Cnd1_N PF12922.7 OQR85904.1 - 8.1e-16 58.3 2.0 8.1e-16 58.3 2.0 2.5 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1, N-term HEAT PF02985.22 OQR85904.1 - 3.3e-07 30.0 1.0 0.63 10.5 0.0 6.2 6 0 0 6 6 6 2 HEAT repeat Cnd3 PF12719.7 OQR85904.1 - 4.7e-05 22.7 1.4 0.0008 18.7 0.2 3.1 2 0 0 2 2 2 1 Nuclear condensing complex subunits, C-term domain HEAT_2 PF13646.6 OQR85904.1 - 0.00015 22.1 0.1 0.28 11.6 0.0 5.6 5 0 0 5 5 5 1 HEAT repeats hSH3 PF14603.6 OQR85904.1 - 0.069 13.6 0.6 0.36 11.3 0.0 2.5 2 0 0 2 2 2 0 Helically-extended SH3 domain DUF4441 PF14536.6 OQR85904.1 - 0.6 10.3 6.9 2.2 8.5 0.4 3.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4441) FtsJ PF01728.19 OQR85906.1 - 1.4e-56 191.4 0.4 2.1e-56 190.8 0.1 1.4 2 0 0 2 2 2 1 FtsJ-like methyltransferase DUF3381 PF11861.8 OQR85906.1 - 3.8e-33 114.6 0.3 7.9e-33 113.6 0.3 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3381) SepSecS PF05889.13 OQR85906.1 - 0.079 11.6 0.4 0.21 10.2 0.1 1.7 2 0 0 2 2 2 0 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS ABC_membrane PF00664.23 OQR85908.1 - 3.1e-17 63.1 22.8 4e-17 62.8 22.8 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region UNC-50 PF05216.13 OQR85909.1 - 2.8e-28 99.0 5.1 3.2e-28 98.8 5.1 1.1 1 0 0 1 1 1 1 UNC-50 family YfzA PF14118.6 OQR85909.1 - 0.0037 17.6 1.1 0.0056 17.1 1.1 1.3 1 0 0 1 1 1 1 YfzA-like protein Tail_VII PF17091.5 OQR85909.1 - 0.035 14.0 0.4 0.076 12.9 0.4 1.6 1 0 0 1 1 1 0 Inovirus G7P protein TPH PF13868.6 OQR85910.1 - 1.2e-48 165.5 128.7 1.2e-48 165.5 128.7 2.0 2 0 0 2 2 2 1 Trichohyalin-plectin-homology domain Dynein_light PF01221.18 OQR85911.1 - 2.4e-25 88.7 1.2 2.7e-25 88.5 1.2 1.1 1 0 0 1 1 1 1 Dynein light chain type 1 COOH-NH2_lig PF14395.6 OQR85911.1 - 0.002 17.4 0.0 0.0023 17.2 0.0 1.1 1 0 0 1 1 1 1 Phage phiEco32-like COOH.NH2 ligase-type 2 DUF4854 PF16146.5 OQR85911.1 - 0.025 14.9 0.1 0.032 14.5 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4854) ApoO PF09769.9 OQR85911.1 - 0.056 13.4 0.0 0.062 13.3 0.0 1.1 1 0 0 1 1 1 0 Apolipoprotein O Ground-like PF04155.18 OQR85911.1 - 0.081 13.6 0.1 0.12 13.1 0.1 1.3 1 0 0 1 1 1 0 Ground-like domain RhoGAP PF00620.27 OQR85912.1 - 3.1e-06 27.1 1.7 5.1e-06 26.4 0.0 2.1 2 1 0 2 2 2 1 RhoGAP domain IQ PF00612.27 OQR85912.1 - 0.00014 21.4 2.1 0.00032 20.2 2.1 1.7 1 0 0 1 1 1 1 IQ calmodulin-binding motif ATP-gua_Ptrans PF00217.19 OQR85932.1 - 4.2e-151 500.2 0.0 5e-77 258.1 0.0 2.1 2 0 0 2 2 2 2 ATP:guanido phosphotransferase, C-terminal catalytic domain ATP-gua_PtransN PF02807.15 OQR85932.1 - 5.3e-62 206.1 0.0 1.3e-29 102.4 0.0 2.4 2 0 0 2 2 2 2 ATP:guanido phosphotransferase, N-terminal domain DUF3420 PF11900.8 OQR85932.1 - 0.0029 17.7 0.0 0.22 11.7 0.0 2.7 2 0 0 2 2 2 1 Domain of unknown function (DUF3420) XFP_N PF09364.10 OQR85932.1 - 0.12 11.1 0.0 3.8 6.2 0.0 2.1 2 0 0 2 2 2 0 XFP N-terminal domain Acyl_transf_3 PF01757.22 OQR85933.1 - 7.7e-20 71.2 31.6 2.1e-19 69.8 31.2 1.8 1 1 1 2 2 2 1 Acyltransferase family YlaH PF14036.6 OQR85933.1 - 1.7 9.0 8.8 0.45 10.9 2.1 2.5 2 0 0 2 2 2 0 YlaH-like protein TraX PF05857.11 OQR85948.1 - 0.0016 18.5 1.7 0.0021 18.2 1.7 1.1 1 0 0 1 1 1 1 TraX protein Gly-zipper_Omp PF13488.6 OQR85949.1 - 0.02 14.9 3.8 0.028 14.4 3.8 1.2 1 0 0 1 1 1 0 Glycine zipper Malate_DH PF12434.8 OQR85949.1 - 0.5 10.4 2.5 0.79 9.8 2.5 1.3 1 0 0 1 1 1 0 Malate dehydrogenase enzyme zf-RING_2 PF13639.6 OQR85950.1 - 4.7e-13 49.3 11.6 4.7e-13 49.3 11.6 2.4 2 0 0 2 2 2 1 Ring finger domain zf-RING_11 PF17123.5 OQR85950.1 - 7e-10 38.5 9.7 2.4e-09 36.8 9.7 2.0 1 0 0 1 1 1 1 RING-like zinc finger zf-rbx1 PF12678.7 OQR85950.1 - 7.7e-07 29.3 12.5 2.7e-06 27.6 12.5 1.9 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 OQR85950.1 - 4.4e-06 26.4 11.1 4.4e-06 26.4 11.1 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 OQR85950.1 - 8.4e-06 25.6 13.8 1.3e-05 24.9 8.0 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 OQR85950.1 - 1.4e-05 24.9 12.2 1.4e-05 24.9 12.2 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OQR85950.1 - 1.6e-05 24.8 11.5 2.8e-05 24.0 6.6 2.6 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 OQR85950.1 - 0.00023 21.1 10.7 0.00023 21.1 10.7 1.9 2 0 0 2 2 2 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 OQR85950.1 - 0.0019 18.2 4.3 0.0019 18.2 4.3 1.8 2 0 0 2 2 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.6 OQR85950.1 - 0.0074 16.1 10.2 0.017 15.0 10.2 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_10 PF16685.5 OQR85950.1 - 0.073 13.2 8.7 0.15 12.2 5.9 2.4 2 0 0 2 2 2 0 zinc RING finger of MSL2 FANCL_C PF11793.8 OQR85950.1 - 0.076 13.2 10.6 0.34 11.1 10.6 2.1 1 1 0 1 1 1 0 FANCL C-terminal domain zf-C3H2C3 PF17122.5 OQR85950.1 - 0.078 13.0 5.8 0.2 11.7 5.8 1.7 1 0 0 1 1 1 0 Zinc-finger RINGv PF12906.7 OQR85950.1 - 2.1 8.5 8.9 5.6 7.2 8.9 1.7 1 1 0 1 1 1 0 RING-variant domain Zn_ribbon_17 PF17120.5 OQR85950.1 - 3.5 7.3 12.9 0.62 9.7 8.8 2.0 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type zf-RING_4 PF14570.6 OQR85950.1 - 4.3 7.2 12.5 0.88 9.4 7.4 2.3 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain Cupin_8 PF13621.6 OQR85953.1 - 9e-24 84.6 0.1 2.2e-23 83.3 0.1 1.6 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.12 OQR85953.1 - 1.8e-05 24.4 0.1 4e-05 23.3 0.0 1.6 2 0 0 2 2 2 1 Cupin superfamily protein JmjC PF02373.22 OQR85953.1 - 0.067 13.6 0.1 0.23 11.9 0.1 2.0 2 0 0 2 2 2 0 JmjC domain, hydroxylase FAD_binding_8 PF08022.12 OQR85965.1 - 2.3e-14 53.4 0.1 5.3e-14 52.2 0.1 1.6 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.12 OQR85965.1 - 1.4e-13 51.2 0.0 2.4e-13 50.5 0.0 1.4 1 0 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.19 OQR85965.1 - 0.00015 21.9 2.2 0.00015 21.9 2.2 2.4 2 0 0 2 2 2 1 Ferric reductase like transmembrane component DUF1668 PF07893.13 OQR85965.1 - 0.008 15.6 0.2 0.029 13.7 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF1668) NAD_binding_1 PF00175.21 OQR85965.1 - 0.016 15.8 0.0 0.086 13.5 0.0 2.0 2 0 0 2 2 2 0 Oxidoreductase NAD-binding domain DUF4271 PF14093.6 OQR85965.1 - 0.2 11.5 7.0 5.7 6.8 3.7 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4271) Peptidase_U4 PF03419.13 OQR85965.1 - 2.7 7.2 5.3 0.96 8.7 0.1 2.1 2 0 0 2 2 2 0 Sporulation factor SpoIIGA Kelch_4 PF13418.6 OQR85966.1 - 1.4e-20 73.0 14.4 2.8e-05 24.0 0.0 7.1 7 1 0 7 7 7 5 Galactose oxidase, central domain EGF_2 PF07974.13 OQR85966.1 - 5.8e-11 42.6 56.0 0.00013 22.3 11.6 4.9 4 0 0 4 4 4 4 EGF-like domain Kelch_5 PF13854.6 OQR85966.1 - 1.8e-10 40.6 21.4 0.0061 16.5 0.4 5.9 5 1 0 5 5 5 3 Kelch motif Kelch_3 PF13415.6 OQR85966.1 - 2e-07 31.1 22.5 0.00052 20.2 0.0 6.9 6 1 0 6 6 6 2 Galactose oxidase, central domain Kelch_6 PF13964.6 OQR85966.1 - 9.4e-05 22.6 17.5 0.064 13.6 0.1 6.6 6 1 0 6 6 6 2 Kelch motif EGF_Tenascin PF18720.1 OQR85966.1 - 0.00013 21.9 11.2 0.00013 21.9 11.2 5.3 5 0 0 5 5 5 3 Tenascin EGF domain Kelch_1 PF01344.25 OQR85966.1 - 0.002 17.7 17.3 0.17 11.5 2.4 6.1 4 2 0 4 4 4 2 Kelch motif Kelch_2 PF07646.15 OQR85966.1 - 0.016 15.2 16.6 1.3 9.1 0.5 6.2 6 1 0 6 6 6 0 Kelch motif hEGF PF12661.7 OQR85966.1 - 0.073 13.7 37.2 0.32 11.7 3.6 5.5 4 0 0 4 4 4 0 Human growth factor-like EGF TPR_2 PF07719.17 OQR85967.1 - 1e-19 69.0 8.0 0.012 15.7 0.0 7.7 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_1 PF00515.28 OQR85967.1 - 1.9e-14 52.8 10.1 0.055 13.3 0.0 7.7 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_6 PF13174.6 OQR85967.1 - 4.5e-13 48.9 1.1 0.2 12.3 0.0 7.5 8 0 0 8 8 7 2 Tetratricopeptide repeat TPR_19 PF14559.6 OQR85967.1 - 5.9e-13 49.1 5.9 0.045 14.3 0.0 5.7 4 1 2 6 6 6 4 Tetratricopeptide repeat ANAPC3 PF12895.7 OQR85967.1 - 2.1e-12 47.1 11.1 0.00046 20.4 0.9 4.6 3 1 1 4 4 4 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.6 OQR85967.1 - 9.4e-11 41.9 12.2 0.006 16.8 0.2 6.6 2 2 5 7 7 7 6 Tetratricopeptide repeat TPR_8 PF13181.6 OQR85967.1 - 1.5e-10 40.4 7.3 0.067 13.4 0.0 7.8 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_14 PF13428.6 OQR85967.1 - 1.4e-09 38.0 0.1 2.9 8.9 0.0 5.8 3 3 2 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.6 OQR85967.1 - 3.7e-09 37.1 0.2 0.0034 18.0 0.2 4.8 3 2 3 6 6 6 1 Tetratricopeptide repeat TPR_7 PF13176.6 OQR85967.1 - 1.4e-08 34.2 6.4 0.26 11.4 0.0 6.5 6 1 1 7 7 7 2 Tetratricopeptide repeat TPR_11 PF13414.6 OQR85967.1 - 1.5e-06 27.8 1.3 0.3 10.8 0.0 5.1 4 1 1 5 5 5 1 TPR repeat TPR_21 PF09976.9 OQR85967.1 - 3.9e-05 23.5 0.2 3.9e-05 23.5 0.2 2.1 2 0 0 2 2 2 1 Tetratricopeptide repeat-like domain TPR_9 PF13371.6 OQR85967.1 - 6.2e-05 23.1 0.1 0.11 12.6 0.0 3.3 3 1 0 3 3 3 2 Tetratricopeptide repeat DUF2225 PF09986.9 OQR85967.1 - 0.0001 22.1 3.3 0.0082 15.9 0.1 3.8 1 1 2 3 3 3 1 Uncharacterized protein conserved in bacteria (DUF2225) Fis1_TPR_C PF14853.6 OQR85967.1 - 0.00046 20.2 3.3 7.1 6.8 0.0 6.1 6 1 1 7 7 6 1 Fis1 C-terminal tetratricopeptide repeat TPR_17 PF13431.6 OQR85967.1 - 0.0014 18.8 2.1 5.4 7.6 0.0 5.0 4 0 0 4 4 4 1 Tetratricopeptide repeat SRP_TPR_like PF17004.5 OQR85967.1 - 0.0037 17.3 8.2 0.19 11.8 0.7 3.8 2 2 0 3 3 3 1 Putative TPR-like repeat TPR_10 PF13374.6 OQR85967.1 - 0.056 13.3 6.9 29 4.7 0.1 5.5 6 0 0 6 6 6 0 Tetratricopeptide repeat DUF4810 PF16068.5 OQR85967.1 - 0.062 13.8 3.9 1.6 9.3 0.0 4.6 6 2 0 7 7 4 0 Domain of unknown function (DUF4810) HrpB1_HrpK PF09613.10 OQR85967.1 - 0.15 11.7 0.5 2.5 7.8 0.0 2.7 3 0 0 3 3 3 0 Bacterial type III secretion protein (HrpB1_HrpK) Glyco_tran_28_C PF04101.16 OQR85967.1 - 0.16 12.0 0.1 0.16 12.0 0.1 2.0 2 0 0 2 2 2 0 Glycosyltransferase family 28 C-terminal domain PPR PF01535.20 OQR85967.1 - 1.1 9.6 6.9 49 4.5 0.0 5.1 6 0 0 6 6 6 0 PPR repeat Myosin_head PF00063.21 OQR85983.1 - 6.3e-47 160.2 0.0 1e-46 159.5 0.0 1.3 1 0 0 1 1 1 1 Myosin head (motor domain) FYVE PF01363.21 OQR85983.1 - 1.6e-14 53.7 12.1 5.1e-14 52.2 12.1 1.9 1 0 0 1 1 1 1 FYVE zinc finger IQ PF00612.27 OQR85983.1 - 4.6e-07 29.1 39.4 0.0055 16.4 1.4 6.3 6 0 0 6 6 6 5 IQ calmodulin-binding motif Calici_MSP PF05752.11 OQR85983.1 - 0.19 11.6 0.9 0.5 10.2 0.9 1.6 1 0 0 1 1 1 0 Calicivirus minor structural protein FTA4 PF13093.6 OQR85983.1 - 3.6 7.4 10.9 10 5.9 10.9 1.9 1 1 0 1 1 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 W2 PF02020.18 OQR85984.1 - 5.8e-19 68.0 0.5 1.3e-18 66.9 0.5 1.6 1 0 0 1 1 1 1 eIF4-gamma/eIF5/eIF2-epsilon TP2 PF01254.18 OQR85992.1 - 0.0089 16.6 7.4 0.021 15.5 7.4 1.5 1 0 0 1 1 1 1 Nuclear transition protein 2 IBR PF01485.21 OQR85992.1 - 3.9 7.8 13.3 10 6.4 0.1 3.5 3 0 0 3 3 3 0 IBR domain, a half RING-finger domain zf-U1 PF06220.12 OQR85992.1 - 5.4 6.9 21.8 3 7.7 1.0 4.0 4 0 0 4 4 4 0 U1 zinc finger PyrI_C PF02748.15 OQR85993.1 - 3.1 7.8 11.0 2.2 8.3 0.2 3.5 4 0 0 4 4 4 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain ABC_tran PF00005.27 OQR86000.1 - 0.001 19.6 0.0 0.0025 18.3 0.0 1.6 2 0 0 2 2 2 1 ABC transporter MCM PF00493.23 OQR86000.1 - 0.015 14.4 0.0 0.025 13.7 0.0 1.2 1 0 0 1 1 1 0 MCM P-loop domain NACHT PF05729.12 OQR86000.1 - 0.02 14.8 0.0 0.038 13.9 0.0 1.6 1 0 0 1 1 1 0 NACHT domain IstB_IS21 PF01695.17 OQR86000.1 - 0.064 13.0 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_29 PF13555.6 OQR86000.1 - 0.087 12.6 0.0 0.22 11.3 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain E7R PF17467.2 OQR86000.1 - 0.09 12.9 0.9 0.32 11.2 0.2 2.4 2 0 0 2 2 2 0 Viral Protein E7 CbiA PF01656.23 OQR86000.1 - 0.11 12.6 0.0 0.28 11.2 0.0 1.6 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain RsgA_GTPase PF03193.16 OQR86000.1 - 0.17 11.8 0.0 0.32 10.9 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase AAA_25 PF13481.6 OQR86000.1 - 0.18 11.3 0.0 0.36 10.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_10 PF12846.7 OQR86000.1 - 0.19 10.6 0.0 0.41 9.5 0.0 1.5 2 0 0 2 2 2 0 AAA-like domain TPR_19 PF14559.6 OQR86008.1 - 1.5e-11 44.6 9.6 0.006 17.1 1.0 5.7 4 2 3 7 7 7 3 Tetratricopeptide repeat TPR_2 PF07719.17 OQR86008.1 - 1.2e-10 40.6 27.7 0.24 11.6 0.0 9.9 10 0 0 10 10 10 3 Tetratricopeptide repeat TPR_12 PF13424.6 OQR86008.1 - 2.4e-08 34.1 14.0 0.034 14.4 0.9 7.0 5 3 1 6 6 6 3 Tetratricopeptide repeat ANAPC3 PF12895.7 OQR86008.1 - 1.1e-07 32.0 24.4 0.00096 19.3 4.3 5.9 3 2 3 6 6 6 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 OQR86008.1 - 3.9e-07 30.3 18.6 0.045 14.4 0.0 7.8 9 0 0 9 9 7 2 Tetratricopeptide repeat TPR_14 PF13428.6 OQR86008.1 - 8.2e-07 29.3 3.5 0.37 11.7 0.0 7.5 6 2 3 9 9 6 1 Tetratricopeptide repeat TPR_16 PF13432.6 OQR86008.1 - 2.2e-06 28.2 8.2 0.14 12.8 0.2 6.1 5 3 2 7 7 6 2 Tetratricopeptide repeat TPR_8 PF13181.6 OQR86008.1 - 2.6e-05 24.1 21.4 0.18 12.1 0.0 7.8 9 0 0 9 9 7 2 Tetratricopeptide repeat TPR_1 PF00515.28 OQR86008.1 - 0.00014 21.5 34.5 0.09 12.6 0.3 9.9 11 0 0 11 11 11 3 Tetratricopeptide repeat TPR_7 PF13176.6 OQR86008.1 - 0.00045 20.0 6.7 5 7.4 0.0 6.3 6 0 0 6 6 6 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 OQR86008.1 - 0.05 13.7 0.2 0.05 13.7 0.2 5.3 6 1 1 7 7 6 0 Fis1 C-terminal tetratricopeptide repeat FIVAR PF07554.13 OQR86008.1 - 0.22 12.3 9.1 0.91 10.3 4.8 3.0 2 0 0 2 2 2 0 FIVAR domain UvrD-helicase PF00580.21 OQR86008.1 - 0.31 10.5 19.9 0.008 15.7 9.8 2.3 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain DUF4519 PF15012.6 OQR86008.1 - 1.2 9.3 5.9 3.1 8.0 5.9 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4519) PHM7_cyt PF14703.6 OQR86008.1 - 1.9 8.7 14.2 8.7 6.5 8.1 3.1 3 2 0 3 3 3 0 Cytosolic domain of 10TM putative phosphate transporter zf-C4H2 PF10146.9 OQR86008.1 - 2.8 8.2 22.5 1.7 8.9 16.0 2.6 2 0 0 2 2 2 0 Zinc finger-containing protein COG2 PF06148.11 OQR86008.1 - 2.8 8.0 22.2 0.86 9.7 0.1 4.1 3 1 0 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 RED_C PF07807.11 OQR86008.1 - 2.9 8.4 8.1 6.9 7.2 6.7 2.4 1 1 0 1 1 1 0 RED-like protein C-terminal region TPR_17 PF13431.6 OQR86008.1 - 5.6 7.6 6.4 3.9 8.1 0.4 4.0 4 0 0 4 4 2 0 Tetratricopeptide repeat Ly49 PF08391.10 OQR86008.1 - 7.8 6.9 11.7 6.6 7.1 6.9 2.9 2 0 0 2 2 2 0 Ly49-like protein, N-terminal region Cas_DxTHG PF09455.10 OQR86008.1 - 8.7 5.8 18.7 1.2 8.7 1.2 2.7 3 0 0 3 3 3 0 CRISPR-associated (Cas) DxTHG family TPR_10 PF13374.6 OQR86008.1 - 8.7 6.4 5.8 20 5.2 0.0 4.5 5 0 0 5 5 4 0 Tetratricopeptide repeat Kinesin_assoc PF16183.5 OQR86008.1 - 8.8 6.4 12.1 2.8 8.1 7.6 2.3 1 1 1 2 2 2 0 Kinesin-associated Lipoxygenase PF00305.19 OQR86011.1 - 1.2e-06 27.3 0.0 1.3e-06 27.2 0.0 1.1 1 0 0 1 1 1 1 Lipoxygenase DUF4507 PF14964.6 OQR86013.1 - 0.097 11.6 0.0 0.15 11.0 0.0 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4507) zf-RING_2 PF13639.6 OQR86038.1 - 1e-12 48.1 8.1 2.8e-12 46.7 8.1 1.8 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 OQR86038.1 - 2.3e-08 33.6 5.3 2.3e-08 33.6 5.3 2.3 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 OQR86038.1 - 1.6e-07 31.1 7.2 1.6e-07 31.1 7.2 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 OQR86038.1 - 6.1e-07 29.2 6.5 1.6e-06 27.9 6.5 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 OQR86038.1 - 6.9e-07 29.5 8.4 3.4e-06 27.3 8.4 2.3 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 OQR86038.1 - 1.6e-06 28.0 5.7 3.3e-06 27.0 5.7 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 OQR86038.1 - 8e-06 25.8 4.6 8e-06 25.8 4.6 2.2 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 OQR86038.1 - 0.0011 18.7 4.8 0.0024 17.7 4.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 OQR86038.1 - 0.0027 17.5 6.6 0.0071 16.2 6.6 1.8 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 Zn_ribbon_17 PF17120.5 OQR86038.1 - 0.0033 17.0 5.0 0.0075 15.9 5.0 1.6 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-ANAPC11 PF12861.7 OQR86038.1 - 0.031 14.3 5.1 0.11 12.6 5.1 2.0 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger FANCL_C PF11793.8 OQR86038.1 - 0.84 9.9 8.2 1.9 8.7 7.2 2.2 2 1 0 2 2 1 0 FANCL C-terminal domain RINGv PF12906.7 OQR86038.1 - 2.8 8.1 11.7 0.71 10.0 7.2 2.4 2 1 0 2 2 2 0 RING-variant domain Smg8_Smg9 PF10220.9 OQR86039.1 - 6.7e-31 107.4 13.0 4e-20 71.8 1.5 3.6 1 1 1 2 2 2 2 Smg8_Smg9 SAP PF02037.27 OQR86040.1 - 0.017 14.9 0.7 5 7.0 0.1 2.3 2 0 0 2 2 2 0 SAP domain T7SS_ESX_EspC PF10824.8 OQR86041.1 - 0.04 14.4 1.1 0.35 11.4 0.1 2.8 2 1 0 3 3 3 0 Excreted virulence factor EspC, type VII ESX diderm MCPsignal PF00015.21 OQR86041.1 - 0.6 9.9 5.7 0.1 12.4 1.0 1.9 2 0 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain DUF16 PF01519.16 OQR86041.1 - 3.9 8.0 8.2 0.74 10.3 1.6 2.4 2 1 0 2 2 2 0 Protein of unknown function DUF16 DUF1690 PF07956.11 OQR86041.1 - 8 6.9 15.4 0.56 10.6 4.3 2.8 2 1 1 3 3 3 0 Protein of Unknown function (DUF1690) Thioredoxin PF00085.20 OQR86049.1 - 1.2e-81 269.4 0.0 4.6e-27 94.0 0.0 3.1 3 0 0 3 3 3 3 Thioredoxin Thioredoxin_2 PF13098.6 OQR86049.1 - 3.5e-17 62.8 0.9 8.4e-05 23.0 0.0 4.6 3 2 0 3 3 3 3 Thioredoxin-like domain Thioredoxin_7 PF13899.6 OQR86049.1 - 5.6e-13 48.9 0.1 0.0035 17.5 0.0 3.6 3 1 1 4 4 4 3 Thioredoxin-like Thioredoxin_8 PF13905.6 OQR86049.1 - 2.1e-12 47.2 0.1 0.011 16.1 0.0 5.5 3 3 3 6 6 6 4 Thioredoxin-like HyaE PF07449.11 OQR86049.1 - 4.6e-12 45.9 0.0 0.019 14.9 0.0 3.5 3 0 0 3 3 3 3 Hydrogenase-1 expression protein HyaE TraF PF13728.6 OQR86049.1 - 2.5e-10 40.6 0.0 0.0034 17.2 0.0 3.1 3 0 0 3 3 3 2 F plasmid transfer operon protein AhpC-TSA PF00578.21 OQR86049.1 - 3.2e-09 36.8 0.2 0.13 12.2 0.0 3.4 3 1 0 3 3 3 3 AhpC/TSA family OST3_OST6 PF04756.13 OQR86049.1 - 4.6e-09 36.1 0.0 0.028 13.8 0.0 3.2 2 1 1 3 3 3 3 OST3 / OST6 family, transporter family Glutaredoxin PF00462.24 OQR86049.1 - 1.9e-08 34.4 0.0 0.015 15.5 0.0 3.5 3 0 0 3 3 3 2 Glutaredoxin Thioredoxin_9 PF14595.6 OQR86049.1 - 5.5e-08 32.6 0.0 0.0012 18.6 0.0 3.1 3 0 0 3 3 3 2 Thioredoxin Thioredoxin_3 PF13192.6 OQR86049.1 - 2.2e-07 30.8 0.0 0.2 11.7 0.0 3.2 3 0 0 3 3 3 2 Thioredoxin domain Redoxin PF08534.10 OQR86049.1 - 2.7e-07 30.4 0.8 0.11 12.2 0.1 3.3 3 0 0 3 3 3 2 Redoxin DUF836 PF05768.14 OQR86049.1 - 3.5e-05 24.1 0.0 3.1 8.3 0.0 3.2 3 0 0 3 3 3 2 Glutaredoxin-like domain (DUF836) Thioredoxin_6 PF13848.6 OQR86049.1 - 0.00031 20.7 0.0 4.6 7.1 0.0 3.2 3 0 0 3 3 3 1 Thioredoxin-like domain DDE_Tnp_1_2 PF13586.6 OQR86049.1 - 0.001 19.4 0.0 12 6.3 0.0 3.2 3 0 0 3 3 3 0 Transposase DDE domain DIM1 PF02966.16 OQR86049.1 - 0.0069 16.2 0.0 14 5.5 0.0 3.0 3 0 0 3 3 3 0 Mitosis protein DIM1 zf_C2H2_ZHX PF18387.1 OQR86049.1 - 0.0092 15.6 0.2 18 5.0 0.0 3.3 3 0 0 3 3 3 0 Zinc-fingers and homeoboxes C2H2 finger domain Thioredoxin_4 PF13462.6 OQR86049.1 - 0.067 13.3 0.1 23 5.1 0.0 3.2 3 1 1 4 4 3 0 Thioredoxin Mu-like_Com PF10122.9 OQR86049.1 - 0.093 12.2 1.6 26 4.4 0.1 3.2 3 0 0 3 3 3 0 Mu-like prophage protein Com DUF4490 PF14892.6 OQR86052.1 - 0.00016 21.7 0.9 0.019 15.0 0.0 3.0 2 1 1 3 3 3 2 Domain of unknown function (DUF4490) FtsX_ECD PF18075.1 OQR86052.1 - 0.011 16.4 0.4 0.76 10.4 0.0 2.2 1 1 1 2 2 2 0 FtsX extracellular domain Adenylsucc_synt PF00709.21 OQR86053.1 - 7.4e-174 578.6 0.0 8.7e-174 578.3 0.0 1.0 1 0 0 1 1 1 1 Adenylosuccinate synthetase LRR_6 PF13516.6 OQR86067.1 - 5.1e-08 32.3 11.2 0.012 15.6 0.2 4.9 5 0 0 5 5 5 4 Leucine Rich repeat LRR_1 PF00560.33 OQR86067.1 - 0.042 14.4 0.9 20 6.2 0.0 3.9 4 0 0 4 4 4 0 Leucine Rich Repeat LRR_4 PF12799.7 OQR86067.1 - 0.058 13.8 8.7 8.2 7.0 0.1 3.9 3 2 2 5 5 5 0 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 OQR86067.1 - 0.062 13.1 6.8 3.7 7.4 0.3 4.0 3 2 0 3 3 3 0 Leucine rich repeat DUF1943 PF09172.11 OQR86067.1 - 4.7 6.4 8.0 2.2 7.4 0.7 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1943) Choline_kinase PF01633.20 OQR86068.1 - 8.3e-54 182.4 0.0 1.3e-53 181.7 0.0 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.23 OQR86068.1 - 1.2e-12 48.3 0.0 2.1e-12 47.5 0.0 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.20 OQR86068.1 - 6e-07 29.1 0.1 1e-06 28.3 0.1 1.4 1 0 0 1 1 1 1 Ecdysteroid kinase Kdo PF06293.14 OQR86068.1 - 0.16 11.3 0.5 0.94 8.8 0.3 2.0 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinesin PF00225.23 OQR86076.1 - 1.2e-117 392.6 1.1 1.4e-117 392.4 0.5 1.4 2 0 0 2 2 2 1 Kinesin motor domain Cyto_heme_lyase PF01265.17 OQR86076.1 - 1.5e-34 120.0 1.6 4.6e-34 118.4 1.6 1.8 1 1 0 1 1 1 1 Cytochrome c/c1 heme lyase Microtub_bd PF16796.5 OQR86076.1 - 4.9e-29 101.2 0.2 1.4e-28 99.7 0.2 1.8 1 0 0 1 1 1 1 Microtubule binding Kinesin_assoc PF16183.5 OQR86076.1 - 0.0082 16.3 5.2 0.0082 16.3 5.2 2.3 2 1 0 2 2 2 1 Kinesin-associated PTSIIB_sorb PF03830.15 OQR86076.1 - 0.038 14.2 0.1 0.12 12.6 0.1 1.8 1 0 0 1 1 1 0 PTS system sorbose subfamily IIB component UPF0154 PF03672.13 OQR86076.1 - 0.16 12.0 0.4 0.53 10.3 0.4 1.8 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0154) Bac_DnaA PF00308.18 OQR86076.1 - 0.18 11.6 1.9 0.31 10.9 0.0 2.1 2 0 0 2 2 2 0 Bacterial dnaA protein VAPB_antitox PF02697.14 OQR86077.1 - 0.043 14.6 1.9 0.058 14.2 0.1 2.1 2 0 0 2 2 2 0 Putative antitoxin DUF5371 PF17341.2 OQR86077.1 - 0.078 13.2 1.1 0.23 11.7 1.1 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5371) zf-C2H2_3 PF13878.6 OQR86077.1 - 0.41 10.5 3.1 1.1 9.1 0.1 3.0 3 0 0 3 3 3 0 zinc-finger of acetyl-transferase ESCO zf-C2H2_4 PF13894.6 OQR86077.1 - 1 10.4 3.9 1.3 10.1 0.6 2.9 3 0 0 3 3 3 0 C2H2-type zinc finger HAD_2 PF13419.6 OQR86087.1 - 3.8e-15 56.4 0.0 4.3e-15 56.3 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 OQR86087.1 - 2.1e-09 38.0 0.0 2.5e-09 37.7 0.0 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 OQR86087.1 - 1.8e-08 34.3 0.0 3e-08 33.6 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like Sulfotransfer_1 PF00685.27 OQR86109.1 - 1.4e-27 96.8 0.0 2.8e-27 95.9 0.0 1.5 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 OQR86109.1 - 0.0012 19.3 0.1 0.0023 18.4 0.1 1.4 1 1 0 1 1 1 1 Sulfotransferase family Biotin_lipoyl PF00364.22 OQR86112.1 - 0.00081 19.2 0.0 0.016 15.1 0.0 2.1 2 0 0 2 2 2 1 Biotin-requiring enzyme OSR1_C PF12202.8 OQR86112.1 - 0.066 13.4 0.1 17 5.7 0.0 2.1 2 0 0 2 2 2 0 Oxidative-stress-responsive kinase 1 C-terminal domain LCAT PF02450.15 OQR86155.1 - 1e-17 64.4 0.1 1.5e-17 63.9 0.1 1.3 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase DUF2076 PF09849.9 OQR86155.1 - 0.022 14.8 0.2 0.032 14.3 0.2 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) TPR_12 PF13424.6 OQR86169.1 - 8.5e-15 54.8 6.7 4.8e-06 26.8 0.5 3.5 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.17 OQR86169.1 - 6e-07 29.1 0.1 0.052 13.7 0.0 3.8 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_10 PF13374.6 OQR86169.1 - 6.2e-07 29.1 1.0 0.012 15.5 0.0 4.5 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_8 PF13181.6 OQR86169.1 - 1.7e-05 24.6 0.2 0.02 15.0 0.0 3.7 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 OQR86169.1 - 0.00024 20.9 2.7 1.5 9.0 0.1 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 OQR86169.1 - 0.0042 16.8 0.1 13 5.8 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat Ank PF00023.30 OQR86170.1 - 1.6e-23 82.0 6.4 1.1e-06 28.7 0.4 4.1 4 0 0 4 4 4 3 Ankyrin repeat Ank_2 PF12796.7 OQR86170.1 - 2.7e-22 79.1 1.9 1e-14 54.8 0.3 2.3 2 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQR86170.1 - 1.1e-21 76.9 0.1 3.4e-10 40.3 0.0 3.1 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 OQR86170.1 - 1.1e-20 73.4 0.4 3.2e-08 33.7 0.1 3.2 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQR86170.1 - 7.1e-19 65.9 0.1 0.00014 22.0 0.0 3.6 3 0 0 3 3 3 3 Ankyrin repeat PseudoU_synth_2 PF00849.22 OQR86171.1 - 6.7e-21 75.0 0.0 7.6e-13 48.9 0.0 2.3 2 0 0 2 2 2 2 RNA pseudouridylate synthase HMG_box PF00505.19 OQR86171.1 - 0.0018 18.6 1.6 0.0036 17.7 1.6 1.4 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 OQR86171.1 - 0.0019 18.8 0.2 0.0043 17.6 0.2 1.6 1 0 0 1 1 1 1 HMG-box domain Ank_4 PF13637.6 OQR86172.1 - 6.2e-24 84.1 0.7 1.5e-10 41.4 0.0 3.0 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 OQR86172.1 - 6.6e-21 74.1 0.1 6.9e-12 45.4 0.1 2.1 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 OQR86172.1 - 7.6e-21 74.5 0.5 2.3e-09 37.7 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 OQR86172.1 - 1.4e-19 69.6 1.7 8.5e-07 29.1 0.0 4.2 4 0 0 4 4 4 4 Ankyrin repeat Ank_3 PF13606.6 OQR86172.1 - 4.4e-18 63.5 0.0 0.00019 21.6 0.0 4.1 4 0 0 4 4 4 4 Ankyrin repeat Ank_2 PF12796.7 OQR86173.1 - 3e-27 95.0 0.0 4.7e-13 49.5 0.0 2.1 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OQR86173.1 - 1e-24 86.2 0.1 4.1e-10 39.7 0.0 3.7 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 OQR86173.1 - 1.5e-23 82.1 0.6 5.3e-06 26.6 0.1 4.2 4 0 0 4 4 4 4 Ankyrin repeat Ank_3 PF13606.6 OQR86173.1 - 8.3e-19 65.7 0.1 0.0042 17.5 0.0 4.2 4 0 0 4 4 4 4 Ankyrin repeat Ank_4 PF13637.6 OQR86173.1 - 5e-17 62.0 0.0 6.3e-09 36.2 0.0 3.8 1 1 2 3 3 3 3 Ankyrin repeats (many copies) PEGA PF08308.11 OQR86173.1 - 0.00024 20.9 0.0 1 9.3 0.0 2.8 3 0 0 3 3 3 2 PEGA domain ATPase PF06745.13 OQR86173.1 - 0.08 12.3 0.0 0.34 10.2 0.0 1.8 2 0 0 2 2 2 0 KaiC Sugar_tr PF00083.24 OQR86174.1 - 3.6e-41 141.5 34.8 1.8e-39 135.9 34.8 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OQR86174.1 - 4.6e-27 94.9 36.0 2.9e-19 69.2 14.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Ycf70 PF17382.2 OQR86174.1 - 3.2 8.2 4.4 6.4 7.3 0.1 3.1 3 0 0 3 3 3 0 Uncharacterized Ycf70-like Sugar_tr PF00083.24 OQR86218.1 - 3.2e-23 82.3 13.7 3.7e-23 82.1 13.7 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OQR86218.1 - 1e-06 28.0 37.2 0.0001 21.4 14.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 OQR86219.1 - 1.5e-27 96.6 6.9 1.9e-27 96.3 6.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OQR86219.1 - 4.5e-20 71.9 12.2 5.3e-20 71.6 12.2 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_4 PF06779.14 OQR86219.1 - 4.5e-06 26.2 6.0 5.7e-06 25.9 6.0 1.2 1 0 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB MFS_2 PF13347.6 OQR86219.1 - 0.17 10.4 9.7 0.24 9.9 9.7 1.2 1 0 0 1 1 1 0 MFS/sugar transport protein UFD1 PF03152.14 OQR86220.1 - 6.8e-31 107.0 0.0 1.1e-30 106.4 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 UBX PF00789.20 OQR86220.1 - 4e-09 36.5 0.0 1e-08 35.2 0.0 1.7 1 0 0 1 1 1 1 UBX domain FG-GAP PF01839.23 OQR86221.1 - 6.4e-05 23.0 1.1 0.4 10.9 0.3 2.7 2 0 0 2 2 2 2 FG-GAP repeat VCBS PF13517.6 OQR86221.1 - 0.00012 22.6 0.1 0.00034 21.1 0.1 1.9 1 0 0 1 1 1 1 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella BBS2_Mid PF14783.6 OQR86221.1 - 0.013 15.5 0.1 6.1 6.9 0.0 3.0 3 0 0 3 3 3 0 Ciliary BBSome complex subunit 2, middle region Itfg2 PF15907.5 OQR86221.1 - 0.11 11.6 0.8 10 5.0 0.4 2.2 1 1 0 2 2 2 0 Integrin-alpha FG-GAP repeat-containing protein 2 Ank_5 PF13857.6 OQR86222.1 - 1.1e-08 35.2 0.1 0.00014 22.1 0.0 3.8 1 1 3 4 4 4 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 OQR86222.1 - 1.2e-07 32.2 0.5 8.5e-06 26.3 0.3 2.4 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQR86222.1 - 1.9e-07 31.5 0.1 1.2e-06 28.9 0.0 2.3 2 1 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQR86222.1 - 9.4e-05 22.5 0.0 1.1 10.0 0.0 4.0 5 0 0 5 5 5 2 Ankyrin repeat DUF5049 PF16468.5 OQR86222.1 - 0.00036 20.4 2.0 0.66 9.9 0.1 3.1 3 2 1 4 4 4 2 Domain of unknown function (DUF5049) YqbF PF14553.6 OQR86222.1 - 0.038 13.9 0.8 8.3 6.4 0.1 3.3 3 0 0 3 3 3 0 YqbF, hypothetical protein domain DUF4215 PF13948.6 OQR86222.1 - 0.054 13.9 4.2 0.13 12.8 4.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4215) SRR1 PF07985.12 OQR86223.1 - 1.6e-08 34.5 0.0 3e-08 33.6 0.0 1.5 1 0 0 1 1 1 1 SRR1 MEA1 PF06910.11 OQR86223.1 - 0.1 13.2 1.1 0.18 12.4 1.1 1.4 1 0 0 1 1 1 0 Male enhanced antigen 1 (MEA1) MBF1 PF08523.10 OQR86223.1 - 0.22 12.0 3.1 0.42 11.1 3.1 1.4 1 0 0 1 1 1 0 Multiprotein bridging factor 1 p450 PF00067.22 OQR86244.1 - 2.9e-49 168.1 0.8 3.7e-49 167.7 0.8 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF1548 PF07579.11 OQR86244.1 - 0.27 11.6 2.5 7.8 6.8 0.1 3.3 2 1 2 4 4 4 0 Domain of Unknown Function (DUF1548) MgtE PF01769.16 OQR86278.1 - 1.8e-14 54.2 9.3 1.8e-14 54.2 9.3 1.8 2 0 0 2 2 2 1 Divalent cation transporter Romo1 PF10247.9 OQR86278.1 - 0.075 13.4 3.1 0.25 11.7 3.1 1.9 1 1 0 1 1 1 0 Reactive mitochondrial oxygen species modulator 1 RicinB_lectin_2 PF14200.6 OQR86307.1 - 2.1e-08 34.8 16.5 0.3 11.8 0.4 6.3 2 2 3 6 6 6 5 Ricin-type beta-trefoil lectin domain-like FRG1 PF06229.12 OQR86307.1 - 1.8e-07 31.0 0.0 3.6 7.3 0.0 6.4 5 2 1 7 7 7 2 FRG1-like domain TonB_2 PF13103.6 OQR86307.1 - 0.0032 17.7 0.0 4.3 7.6 0.0 3.0 3 0 0 3 3 3 2 TonB C terminal CID_GANP PF16766.5 OQR86307.1 - 0.018 15.2 0.1 33 4.8 0.1 4.7 6 0 0 6 6 6 0 Binding region of GANP to ENY2 Peptidase_C16 PF01831.17 OQR86307.1 - 0.044 13.5 0.2 6.5 6.4 0.0 3.4 3 1 1 4 4 4 0 Peptidase C16 family Hormone_6 PF00236.18 OQR86307.1 - 2.8 8.0 17.4 41 4.3 0.1 7.5 9 0 0 9 9 9 0 Glycoprotein hormone DUF3280 PF11684.8 OQR86307.1 - 4.3 7.8 12.7 1e+02 3.3 0.1 6.4 8 0 0 8 8 8 0 Protein of unknown function (DUF2380) PhoLip_ATPase_N PF16209.5 OQR86322.1 - 2.7e-21 75.0 2.6 2.7e-21 75.0 2.6 1.9 2 0 0 2 2 2 1 Phospholipid-translocating ATPase N-terminal Cation_ATPase PF13246.6 OQR86322.1 - 1.5e-11 44.2 0.0 8e-11 41.9 0.0 2.1 2 0 0 2 2 2 1 Cation transport ATPase (P-type) E1-E2_ATPase PF00122.20 OQR86322.1 - 1.3e-07 31.4 0.0 6.7e-07 29.0 0.0 2.2 1 1 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.26 OQR86322.1 - 1.9e-06 28.3 1.2 4e-05 24.0 1.2 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase DUF1826 PF08856.11 OQR86322.1 - 0.11 12.5 0.3 0.45 10.4 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1826) Bromodomain PF00439.25 OQR86328.1 - 1.3e-13 50.8 0.0 1.9e-13 50.3 0.0 1.3 1 0 0 1 1 1 1 Bromodomain ERK-JNK_inhib PF15002.6 OQR86328.1 - 0.00043 20.0 3.1 0.0007 19.3 3.1 1.4 1 0 0 1 1 1 1 ERK and JNK pathways, inhibitor Peptidase_S49_N PF08496.10 OQR86328.1 - 1.3 9.1 6.4 2 8.5 6.4 1.3 1 0 0 1 1 1 0 Peptidase family S49 N-terminal E1_UFD PF09358.10 OQR86329.1 - 0.19 12.5 0.0 0.32 11.7 0.0 1.3 1 0 0 1 1 1 0 Ubiquitin fold domain Ank_2 PF12796.7 OQR86355.1 - 1.5e-42 144.0 15.9 2.1e-15 57.0 0.9 5.9 2 2 4 6 6 6 5 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OQR86355.1 - 2.1e-25 86.0 5.9 0.0024 18.2 0.0 9.8 9 0 0 9 9 9 5 Ankyrin repeat Ank_4 PF13637.6 OQR86355.1 - 7.1e-25 87.1 8.6 2.3e-05 24.9 0.2 7.5 4 3 4 8 8 8 6 Ankyrin repeats (many copies) Ank PF00023.30 OQR86355.1 - 4.3e-24 83.9 7.9 3.1e-05 24.2 0.0 8.0 8 0 0 8 8 8 6 Ankyrin repeat Ank_5 PF13857.6 OQR86355.1 - 4.4e-22 77.8 8.3 0.00013 22.2 0.0 8.4 5 2 3 8 8 8 5 Ankyrin repeats (many copies) PALP PF00291.25 OQR86383.1 - 6.4e-29 101.3 0.0 7.2e-29 101.1 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme zf-C3HC4_3 PF13920.6 OQR86416.1 - 2.3e-09 37.0 9.3 3.1e-09 36.5 9.3 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Ank PF00023.30 OQR86416.1 - 2.2e-07 31.0 0.3 6.6e-07 29.5 0.3 1.8 1 0 0 1 1 1 1 Ankyrin repeat Ank_5 PF13857.6 OQR86416.1 - 8.8e-06 25.9 0.3 1.4e-05 25.2 0.3 1.4 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQR86416.1 - 4.1e-05 23.7 0.2 0.00011 22.4 0.2 1.7 1 0 0 1 1 1 1 Ankyrin repeat zf-C3HC4_2 PF13923.6 OQR86416.1 - 0.0002 21.1 11.1 0.00036 20.3 11.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Ank_4 PF13637.6 OQR86416.1 - 0.00059 20.3 0.0 0.0012 19.4 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (many copies) zf-RING_UBOX PF13445.6 OQR86416.1 - 0.0038 17.2 6.1 0.0089 16.0 5.9 1.7 1 1 0 1 1 1 1 RING-type zinc-finger zf-RING_2 PF13639.6 OQR86416.1 - 0.0048 17.2 10.6 0.0072 16.6 10.6 1.3 1 0 0 1 1 1 1 Ring finger domain Ank_2 PF12796.7 OQR86416.1 - 0.0062 17.1 0.0 0.014 16.0 0.0 1.6 2 0 0 2 2 1 1 Ankyrin repeats (3 copies) zf-C3HC4 PF00097.25 OQR86416.1 - 0.0081 16.0 12.6 0.015 15.1 12.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 OQR86416.1 - 0.019 14.8 9.8 0.033 14.0 9.8 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 TerY_C PF15616.6 OQR86416.1 - 0.061 13.4 3.9 0.085 13.0 3.9 1.2 1 0 0 1 1 1 0 TerY-C metal binding domain zf-RING_4 PF14570.6 OQR86416.1 - 0.075 12.8 10.7 2.1 8.2 10.7 2.2 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain DUF1797 PF08796.10 OQR86416.1 - 0.13 12.4 1.0 7.3 6.8 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1797) zf-RING_5 PF14634.6 OQR86416.1 - 0.18 11.8 12.3 0.32 11.0 12.3 1.4 1 0 0 1 1 1 0 zinc-RING finger domain DUF2039 PF10217.9 OQR86416.1 - 0.23 11.8 9.6 0.5 10.7 9.2 1.7 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2039) zf-P11 PF03854.14 OQR86416.1 - 0.52 10.0 9.7 2.5 7.8 9.8 2.0 1 1 0 1 1 1 0 P-11 zinc finger Ank_5 PF13857.6 OQR86417.1 - 3.9e-05 23.9 0.0 5.5e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 OQR86417.1 - 0.0038 17.8 0.0 0.0041 17.7 0.0 1.2 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 OQR86417.1 - 0.014 16.0 0.0 0.014 16.0 0.0 1.1 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) Gag_MA PF01140.19 OQR86417.1 - 0.088 12.5 0.1 0.11 12.3 0.1 1.1 1 0 0 1 1 1 0 Matrix protein (MA), p15 Sugar_tr PF00083.24 OQR86436.1 - 2.1e-50 171.9 10.6 3e-50 171.4 10.6 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OQR86436.1 - 2.2e-15 56.4 14.3 3.9e-15 55.6 13.8 1.6 1 1 1 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 OQR86436.1 - 0.0022 16.5 4.0 0.0033 15.9 4.0 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Ion_trans_2 PF07885.16 OQR86453.1 - 8.5e-09 35.3 0.3 1.4e-08 34.6 0.3 1.3 1 0 0 1 1 1 1 Ion channel Ion_trans PF00520.31 OQR86453.1 - 2.8e-06 26.7 0.2 3.7e-06 26.4 0.2 1.2 1 0 0 1 1 1 1 Ion transport protein EF-hand_1 PF00036.32 OQR86453.1 - 0.0038 16.7 0.1 0.017 14.6 0.0 2.3 1 1 1 2 2 2 1 EF hand DUF1506 PF07405.11 OQR86453.1 - 0.089 13.0 0.1 0.13 12.4 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1506) EF-hand_7 PF13499.6 OQR86453.1 - 0.099 13.1 2.7 0.17 12.4 0.9 2.3 1 1 1 2 2 2 0 EF-hand domain pair EF-hand_6 PF13405.6 OQR86453.1 - 0.29 11.2 1.1 1.2 9.3 0.1 2.6 3 1 0 3 3 3 0 EF-hand domain Allexi_40kDa PF05549.11 OQR86453.1 - 0.34 10.4 4.7 0.46 10.0 4.7 1.2 1 0 0 1 1 1 0 Allexivirus 40kDa protein AstE_AspA PF04952.14 OQR86454.1 - 2.9e-14 52.8 0.0 3.6e-14 52.5 0.0 1.3 1 1 0 1 1 1 1 Succinylglutamate desuccinylase / Aspartoacylase family Ank_2 PF12796.7 OQR86479.1 - 2e-16 60.3 2.8 3.9e-11 43.4 0.6 2.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQR86479.1 - 5.7e-15 55.5 4.4 3.4e-10 40.2 0.5 2.9 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 OQR86479.1 - 1.9e-12 47.2 1.4 9.3e-12 45.0 1.3 2.0 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.30 OQR86479.1 - 5.8e-11 42.3 2.8 2.8e-06 27.5 0.6 3.5 3 1 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.6 OQR86479.1 - 8.6e-11 41.1 0.3 0.00014 22.0 0.1 3.5 3 0 0 3 3 3 2 Ankyrin repeat zf-C3HC4_3 PF13920.6 OQR86479.1 - 5.9e-10 38.8 8.5 5.9e-10 38.8 8.5 2.9 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) DZR PF12773.7 OQR86479.1 - 4e-05 23.5 14.6 0.044 13.8 14.6 2.6 1 1 0 1 1 1 1 Double zinc ribbon zf-C3HC4 PF00097.25 OQR86479.1 - 0.0018 18.1 12.2 0.0018 18.1 12.2 2.8 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 OQR86479.1 - 0.0038 17.0 11.0 0.0038 17.0 11.0 2.9 2 1 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) FeS PF04060.13 OQR86479.1 - 0.043 13.5 0.8 0.043 13.5 0.8 2.8 2 1 1 3 3 3 0 Putative Fe-S cluster DUF2039 PF10217.9 OQR86479.1 - 0.22 11.9 10.8 0.17 12.2 8.7 2.0 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2039) DUF4833 PF16117.5 OQR86480.1 - 7.8e-15 55.1 0.0 1.2e-14 54.5 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4833) START PF01852.19 OQR86480.1 - 1.7e-06 27.6 0.0 3.5e-06 26.6 0.0 1.5 1 0 0 1 1 1 1 START domain PX PF00787.24 OQR86480.1 - 5.9e-06 26.2 0.0 1.8e-05 24.7 0.0 1.8 1 0 0 1 1 1 1 PX domain HHH_8 PF14716.6 OQR86509.1 - 3.8e-13 49.6 0.1 6.4e-13 48.9 0.1 1.4 1 0 0 1 1 1 1 Helix-hairpin-helix domain AMP-binding PF00501.28 OQR86510.1 - 7.8e-87 291.6 0.0 9.4e-87 291.3 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 OQR86510.1 - 4.3e-14 53.2 0.7 1.8e-13 51.3 0.7 2.1 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain CDP-OH_P_transf PF01066.21 OQR86511.1 - 2.1e-16 60.4 0.2 2.1e-16 60.4 0.2 3.1 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase RRM_5 PF13893.6 OQR86512.1 - 4.9e-41 139.2 0.0 4.4e-20 71.5 0.0 4.1 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.22 OQR86512.1 - 5e-26 90.3 1.1 2.8e-07 30.3 0.1 4.3 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_8 PF11835.8 OQR86512.1 - 6.7e-13 48.7 0.5 2.5e-12 46.8 0.3 2.0 2 0 0 2 2 2 1 RRM-like domain RRM_occluded PF16842.5 OQR86512.1 - 5.7e-07 29.3 0.0 0.87 9.5 0.0 4.2 4 0 0 4 4 4 2 Occluded RNA-recognition motif Limkain-b1 PF11608.8 OQR86512.1 - 0.0017 18.4 0.1 0.3 11.2 0.0 2.7 2 0 0 2 2 2 1 Limkain b1 BT1 PF03092.16 OQR86536.1 - 7.5e-20 70.6 32.9 5.7e-10 38.0 2.5 5.1 5 2 1 6 6 6 3 BT1 family PUCC PF03209.15 OQR86536.1 - 4.4e-06 26.0 4.7 0.0017 17.5 0.1 3.0 3 0 0 3 3 3 2 PUCC protein MtN3_slv PF03083.16 OQR86537.1 - 2 8.5 8.8 1.3 9.2 0.1 4.1 4 0 0 4 4 4 0 Sugar efflux transporter for intercellular exchange DUF2897 PF11446.8 OQR86538.1 - 0.023 14.6 0.9 0.023 14.6 0.9 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2897) Med22 PF06179.12 OQR86541.1 - 6e-18 65.0 0.9 7.1e-18 64.8 0.9 1.1 1 0 0 1 1 1 1 Surfeit locus protein 5 subunit 22 of Mediator complex HMG_box PF00505.19 OQR86542.1 - 3e-14 53.2 2.0 5.3e-14 52.4 2.0 1.4 1 0 0 1 1 1 1 HMG (high mobility group) box SNF5 PF04855.12 OQR86542.1 - 2.3e-13 50.5 0.5 1e-12 48.4 0.0 1.9 2 0 0 2 2 2 1 SNF5 / SMARCB1 / INI1 HMG_box_2 PF09011.10 OQR86542.1 - 7.9e-07 29.6 3.5 1.5e-06 28.7 3.5 1.5 1 0 0 1 1 1 1 HMG-box domain Na_trans_assoc PF06512.13 OQR86542.1 - 0.0091 16.3 4.4 0.013 15.7 4.4 1.3 1 0 0 1 1 1 1 Sodium ion transport-associated MATalpha_HMGbox PF04769.12 OQR86542.1 - 0.049 12.9 0.2 0.067 12.5 0.2 1.2 1 0 0 1 1 1 0 Mating-type protein MAT alpha 1 HMG-box Protamine_like PF06382.11 OQR86542.1 - 0.11 12.7 0.1 0.17 12.1 0.1 1.2 1 0 0 1 1 1 0 Protamine and protamine like NOA36 PF06524.12 OQR86542.1 - 6.1 6.1 10.2 8.3 5.6 10.2 1.2 1 0 0 1 1 1 0 NOA36 protein ABC2_membrane PF01061.24 OQR86560.1 - 1.9e-35 122.2 30.8 1.9e-35 122.2 30.8 1.8 2 0 0 2 2 2 1 ABC-2 type transporter ABC_tran PF00005.27 OQR86560.1 - 3e-14 53.7 0.0 1.4e-12 48.3 0.0 2.3 2 0 0 2 2 2 1 ABC transporter PDR_assoc PF08370.11 OQR86560.1 - 7e-05 22.5 1.1 7e-05 22.5 1.1 3.1 3 0 0 3 3 3 1 Plant PDR ABC transporter associated ABC2_membrane_3 PF12698.7 OQR86560.1 - 0.004 16.3 19.2 0.004 16.3 19.2 1.9 1 1 1 2 2 2 1 ABC-2 family transporter protein DUF4227 PF14004.6 OQR86560.1 - 0.025 14.5 0.2 0.025 14.5 0.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4227) DUF4878 PF12870.7 OQR86565.1 - 0.033 14.5 0.0 0.044 14.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4878) CDP-OH_P_transf PF01066.21 OQR86565.1 - 0.18 12.6 0.3 0.35 11.7 0.2 1.5 1 1 0 1 1 1 0 CDP-alcohol phosphatidyltransferase AhpC-TSA PF00578.21 OQR86566.1 - 7.7e-17 61.4 0.0 8.3e-17 61.3 0.0 1.0 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 OQR86566.1 - 2e-07 30.8 0.0 2.4e-07 30.5 0.0 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA_2 PF13911.6 OQR86566.1 - 4.6e-05 23.5 0.0 6.3e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme CECR6_TMEM121 PF14997.6 OQR86568.1 - 0.066 13.0 0.3 0.08 12.8 0.3 1.2 1 0 0 1 1 1 0 CECR6/TMEM121 family DnaJ PF00226.31 OQR86593.1 - 2.6e-18 65.9 1.8 4.1e-18 65.3 1.8 1.3 1 0 0 1 1 1 1 DnaJ domain Thr_synth_N PF14821.6 OQR86594.1 - 3.6e-30 104.0 0.0 2.4e-29 101.4 0.0 2.3 2 0 0 2 2 2 1 Threonine synthase N terminus PALP PF00291.25 OQR86594.1 - 1.7e-17 63.8 0.0 8.8e-17 61.4 0.0 1.8 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Fib_alpha PF08702.10 OQR86597.1 - 0.0093 16.2 2.9 0.52 10.5 2.1 2.5 2 0 0 2 2 2 1 Fibrinogen alpha/beta chain family Mt_ATP-synt_B PF05405.14 OQR86597.1 - 0.82 9.3 4.3 1.7 8.3 0.0 3.1 3 1 1 4 4 4 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) DUF842 PF05811.13 OQR86597.1 - 2.9 7.6 7.8 0.8 9.4 3.1 2.3 3 0 0 3 3 3 0 Eukaryotic protein of unknown function (DUF842) SlyX PF04102.12 OQR86597.1 - 9.7 6.9 9.2 11 6.7 1.1 3.7 4 0 0 4 4 4 0 SlyX PH PF00169.29 OQR86605.1 - 0.004 17.7 0.0 0.022 15.3 0.0 2.0 1 1 1 2 2 2 1 PH domain PH_11 PF15413.6 OQR86605.1 - 0.092 13.2 0.2 0.47 10.9 0.4 1.9 1 1 1 2 2 2 0 Pleckstrin homology domain PI3_PI4_kinase PF00454.27 OQR86606.1 - 5.8e-46 157.3 0.1 3.5e-44 151.5 0.1 2.6 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.20 OQR86606.1 - 4.4e-45 153.4 0.6 7.7e-45 152.6 0.6 1.4 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PH PF00169.29 OQR86606.1 - 2.2e-15 57.0 0.3 6.5e-15 55.5 0.3 1.9 1 0 0 1 1 1 1 PH domain PI3K_C2 PF00792.24 OQR86606.1 - 3.4e-11 43.2 0.0 7.7e-11 42.1 0.0 1.6 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 PI3K_rbd PF00794.18 OQR86606.1 - 3e-08 33.8 0.4 7.8e-08 32.5 0.4 1.7 1 0 0 1 1 1 1 PI3-kinase family, ras-binding domain PH_11 PF15413.6 OQR86606.1 - 0.00036 20.9 1.0 0.0011 19.3 1.0 1.9 1 0 0 1 1 1 1 Pleckstrin homology domain PH_8 PF15409.6 OQR86606.1 - 0.0044 17.3 0.8 0.15 12.3 0.0 3.4 4 0 0 4 4 4 1 Pleckstrin homology domain DUF4135 PF13575.6 OQR86606.1 - 0.06 12.7 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4135) DENN PF02141.21 OQR86607.1 - 4.2e-27 95.3 2.1 1.1e-26 94.0 2.1 1.7 1 0 0 1 1 1 1 DENN (AEX-3) domain uDENN PF03456.18 OQR86607.1 - 5.8e-07 30.2 0.8 1.6e-06 28.8 0.2 2.1 2 0 0 2 2 2 1 uDENN domain dDENN PF03455.19 OQR86607.1 - 0.00017 21.5 2.0 0.00032 20.6 0.4 2.4 2 0 0 2 2 2 1 dDENN domain Zn-ribbon_8 PF09723.10 OQR86607.1 - 0.033 14.3 4.1 0.13 12.4 4.1 2.0 1 0 0 1 1 1 0 Zinc ribbon domain PDZ_6 PF17820.1 OQR86607.1 - 0.11 12.3 0.0 0.24 11.3 0.0 1.5 1 0 0 1 1 1 0 PDZ domain DZR PF12773.7 OQR86607.1 - 2.3 8.3 6.1 8 6.6 6.1 1.9 1 0 0 1 1 1 0 Double zinc ribbon adh_short PF00106.25 OQR86608.1 - 3.3e-25 88.7 1.1 6.2e-21 74.7 0.2 2.2 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 OQR86608.1 - 3.1e-17 62.9 0.0 7.9e-12 45.2 0.1 2.2 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OQR86608.1 - 6.3e-09 36.0 0.1 1.1e-08 35.3 0.1 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 OQR86608.1 - 0.00014 21.5 0.7 0.081 12.4 0.1 2.2 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 OQR86608.1 - 0.0066 15.6 0.1 0.0092 15.1 0.1 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein PDZ_6 PF17820.1 OQR86623.1 - 6.3e-06 25.9 0.0 1.4e-05 24.8 0.0 1.6 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 OQR86623.1 - 6.7e-06 26.3 0.0 1.7e-05 25.0 0.0 1.7 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 OQR86623.1 - 0.00064 20.0 0.0 0.0022 18.3 0.0 2.0 1 0 0 1 1 1 1 PDZ domain PLATZ PF04640.14 OQR86623.1 - 0.51 11.0 5.4 0.15 12.7 0.6 2.6 3 0 0 3 3 3 0 PLATZ transcription factor LMBR1 PF04791.16 OQR86623.1 - 3.9 6.3 5.6 5.7 5.7 5.6 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein ABC_tran PF00005.27 OQR86668.1 - 4.6e-08 33.7 1.0 7.3e-08 33.0 1.0 1.3 1 1 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 OQR86668.1 - 7.2e-06 26.0 0.4 8.2e-06 25.8 0.4 1.0 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 OQR86668.1 - 1.5e-05 24.7 0.1 2.3e-05 24.0 0.1 1.3 1 0 0 1 1 1 1 P-loop containing region of AAA domain SMC_N PF02463.19 OQR86668.1 - 0.00013 21.4 0.0 0.00014 21.4 0.0 1.1 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 OQR86668.1 - 0.00041 20.3 0.0 0.00041 20.3 0.0 1.2 1 0 0 1 1 1 1 RsgA GTPase MMR_HSR1 PF01926.23 OQR86668.1 - 0.0012 18.9 0.3 0.0018 18.4 0.3 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_30 PF13604.6 OQR86668.1 - 0.0023 17.7 0.0 0.0025 17.5 0.0 1.1 1 0 0 1 1 1 1 AAA domain Dynamin_N PF00350.23 OQR86668.1 - 0.0027 17.8 0.0 0.0028 17.7 0.0 1.3 1 0 0 1 1 1 1 Dynamin family AAA_23 PF13476.6 OQR86668.1 - 0.0027 18.3 0.6 0.0031 18.0 0.6 1.3 1 1 0 1 1 1 1 AAA domain AAA_15 PF13175.6 OQR86668.1 - 0.0034 17.2 0.0 0.0035 17.1 0.0 1.1 1 0 0 1 1 1 1 AAA ATPase domain cobW PF02492.19 OQR86668.1 - 0.0039 16.8 0.0 0.0043 16.7 0.0 1.1 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_16 PF13191.6 OQR86668.1 - 0.0041 17.5 0.0 0.0044 17.4 0.0 1.1 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 OQR86668.1 - 0.008 16.5 0.0 0.0087 16.3 0.0 1.2 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 OQR86668.1 - 0.0091 15.1 0.1 0.0091 15.1 0.1 1.2 1 0 0 1 1 1 1 Type II/IV secretion system protein Zeta_toxin PF06414.12 OQR86668.1 - 0.011 15.1 0.1 0.014 14.7 0.1 1.2 1 0 0 1 1 1 0 Zeta toxin DUF815 PF05673.13 OQR86668.1 - 0.011 14.9 0.0 0.011 14.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_7 PF12775.7 OQR86668.1 - 0.013 15.0 0.0 0.015 14.8 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region TrwB_AAD_bind PF10412.9 OQR86668.1 - 0.024 13.5 0.1 0.034 13.1 0.1 1.2 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain AAA_11 PF13086.6 OQR86668.1 - 0.055 13.2 0.1 0.059 13.1 0.1 1.1 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.9 OQR86668.1 - 0.058 12.6 0.0 0.058 12.6 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_25 PF13481.6 OQR86668.1 - 0.06 12.9 0.0 0.066 12.8 0.0 1.1 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 OQR86668.1 - 0.086 12.8 0.0 0.098 12.6 0.0 1.2 1 0 0 1 1 1 0 NACHT domain FtsK_SpoIIIE PF01580.18 OQR86668.1 - 0.095 12.0 0.1 0.12 11.7 0.1 1.2 1 0 0 1 1 1 0 FtsK/SpoIIIE family PhoH PF02562.16 OQR86668.1 - 0.11 12.0 0.1 0.12 11.8 0.1 1.2 1 0 0 1 1 1 0 PhoH-like protein AAA_27 PF13514.6 OQR86668.1 - 0.14 11.7 0.0 0.18 11.4 0.0 1.2 1 0 0 1 1 1 0 AAA domain DUF3694 PF12473.8 OQR86669.1 - 2.2e-05 25.2 0.6 8.9e-05 23.2 0.4 2.2 2 0 0 2 2 2 1 Kinesin protein GHMP_kinases_N PF00288.26 OQR86727.1 - 3e-12 46.6 1.6 4.8e-12 45.9 0.4 2.0 2 0 0 2 2 2 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 OQR86727.1 - 4.3e-08 33.4 0.1 8.9e-08 32.4 0.1 1.5 1 0 0 1 1 1 1 GHMP kinases C terminal Peptidase_M8 PF01457.16 OQR86731.1 - 1.2e-29 103.4 12.1 1.5e-28 99.8 12.1 2.2 1 1 0 1 1 1 1 Leishmanolysin EGF_2 PF07974.13 OQR86731.1 - 0.00035 20.9 27.9 0.0021 18.4 11.5 5.9 5 1 1 6 6 6 3 EGF-like domain PT PF04886.12 OQR86747.1 - 4e-16 58.3 165.8 5.8e-07 28.9 18.3 7.7 2 2 4 6 6 6 4 PT repeat CAMSAP_CKK PF08683.11 OQR86748.1 - 1.2e-28 99.6 0.1 2.6e-28 98.5 0.1 1.5 1 0 0 1 1 1 1 Microtubule-binding calmodulin-regulated spectrin-associated COMPASS-Shg1 PF05205.12 OQR86748.1 - 8.1 7.2 6.9 1.4 9.6 0.8 2.8 3 0 0 3 3 3 0 COMPASS (Complex proteins associated with Set1p) component shg1 BK_channel_a PF03493.18 OQR86749.1 - 6.1e-22 77.6 0.5 1.8e-19 69.8 0.1 2.9 2 0 0 2 2 2 1 Calcium-activated BK potassium channel alpha subunit Ion_trans PF00520.31 OQR86749.1 - 1e-19 70.8 11.0 1.9e-19 69.9 11.0 1.3 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 OQR86749.1 - 7.8e-12 45.0 1.9 2.1e-11 43.6 1.9 1.8 1 0 0 1 1 1 1 Ion channel TrkA_C PF02080.21 OQR86749.1 - 0.0044 16.8 0.0 0.63 9.9 0.0 2.6 2 0 0 2 2 2 1 TrkA-C domain DUF4106 PF13388.6 OQR86749.1 - 0.012 14.8 1.3 0.18 11.0 0.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4106) TrkA_N PF02254.18 OQR86749.1 - 0.019 15.2 0.1 0.077 13.3 0.1 2.0 2 0 0 2 2 2 0 TrkA-N domain SRC-1 PF08832.10 OQR86749.1 - 0.055 14.5 1.0 0.19 12.8 1.0 1.9 1 0 0 1 1 1 0 Steroid receptor coactivator MPS-4 PF17523.2 OQR86749.1 - 0.42 10.8 3.3 0.94 9.6 0.8 2.6 2 0 0 2 2 2 0 MinK-related peptide, potassium channel accessory sub-unit protein 4 Metallophos PF00149.28 OQR86766.1 - 2.6e-08 34.6 0.1 5e-08 33.7 0.1 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase TRP PF06011.12 OQR86803.1 - 2.2e-21 76.1 24.9 2.2e-21 76.1 24.9 2.2 1 1 1 2 2 2 1 Transient receptor potential (TRP) ion channel DUF4059 PF13268.6 OQR86803.1 - 0.11 13.0 0.3 0.11 13.0 0.3 4.2 4 1 0 4 4 4 0 Protein of unknown function (DUF4059) WD40 PF00400.32 OQR86817.1 - 2e-25 88.5 15.4 4.4e-06 27.3 0.2 9.7 11 0 0 11 11 11 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OQR86817.1 - 5.7e-08 32.9 0.0 0.17 12.2 0.0 4.6 4 0 0 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain EF-hand_5 PF13202.6 OQR86817.1 - 0.0025 17.2 0.2 0.0099 15.3 0.2 2.1 1 0 0 1 1 1 1 EF hand EF-hand_1 PF00036.32 OQR86817.1 - 0.0025 17.3 0.1 0.0025 17.3 0.1 3.1 3 0 0 3 3 3 1 EF hand EF-hand_7 PF13499.6 OQR86817.1 - 0.0031 17.9 0.2 0.011 16.1 0.2 2.1 1 1 0 1 1 1 1 EF-hand domain pair Nup160 PF11715.8 OQR86817.1 - 0.0094 14.6 0.0 0.45 9.1 0.0 2.8 4 0 0 4 4 4 1 Nucleoporin Nup120/160 EF-hand_6 PF13405.6 OQR86817.1 - 0.015 15.2 0.2 0.081 12.9 0.1 2.4 2 0 0 2 2 2 0 EF-hand domain EF-hand_8 PF13833.6 OQR86817.1 - 1.6 8.6 4.0 1.5 8.8 0.1 2.6 2 1 0 2 2 2 0 EF-hand domain pair zf-RING_2 PF13639.6 OQR86836.1 - 4.1e-09 36.6 12.7 4.1e-09 36.6 12.7 2.4 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.7 OQR86836.1 - 5.9e-07 29.7 12.9 1.8e-06 28.1 12.9 1.9 1 0 0 1 1 1 1 RING-H2 zinc finger domain Prok-RING_4 PF14447.6 OQR86836.1 - 8.1e-05 22.4 8.3 0.00012 21.9 7.0 2.0 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 OQR86836.1 - 0.00012 21.9 10.4 0.00012 21.9 10.4 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OQR86836.1 - 0.00058 19.8 13.3 0.0016 18.4 13.3 1.8 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 OQR86836.1 - 0.00064 19.5 11.9 0.00064 19.5 11.9 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 OQR86836.1 - 0.0016 18.3 12.7 0.0016 18.3 12.7 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 OQR86836.1 - 0.015 15.3 6.9 0.053 13.6 6.9 1.9 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.6 OQR86836.1 - 0.074 13.1 15.9 0.048 13.7 11.3 2.6 2 0 0 2 2 2 0 RING-type zinc-finger zf-C3HC4_4 PF15227.6 OQR86836.1 - 0.1 12.8 15.9 0.87 9.8 11.2 3.2 2 1 0 2 2 2 0 zinc finger of C3HC4-type, RING GNT-I PF03071.15 OQR86836.1 - 0.21 10.3 2.8 0.33 9.7 2.8 1.2 1 0 0 1 1 1 0 GNT-I family zf-Nse PF11789.8 OQR86836.1 - 0.49 10.2 6.2 1.3 8.9 6.2 1.8 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_11 PF17123.5 OQR86836.1 - 8.9 6.2 17.6 0.41 10.4 9.9 2.7 3 0 0 3 3 3 0 RING-like zinc finger WD40 PF00400.32 OQR86840.1 - 3.4e-12 46.7 7.7 0.00012 22.8 0.2 4.8 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OQR86840.1 - 3.2e-09 37.0 0.0 0.22 11.8 0.0 5.1 4 1 1 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Frtz PF11768.8 OQR86840.1 - 0.062 11.6 0.0 2.2 6.5 0.0 2.1 2 0 0 2 2 2 0 WD repeat-containing and planar cell polarity effector protein Fritz TUTF7_u4 PF16631.5 OQR86840.1 - 5 7.8 14.1 19 6.0 0.9 2.7 2 0 0 2 2 2 0 Unstructured region 4 on terminal uridylyltransferase 7 RsgA_GTPase PF03193.16 OQR86842.1 - 0.0097 15.8 0.0 0.023 14.6 0.0 1.6 1 0 0 1 1 1 1 RsgA GTPase ABC_tran PF00005.27 OQR86842.1 - 0.071 13.6 0.0 0.17 12.4 0.0 1.6 1 0 0 1 1 1 0 ABC transporter AAA_25 PF13481.6 OQR86842.1 - 0.091 12.3 0.0 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 OQR86842.1 - 0.12 12.1 0.0 0.31 10.8 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain HEAT PF02985.22 OQR86843.1 - 1.2e-09 37.5 5.2 0.17 12.2 0.0 6.8 7 0 0 7 7 7 3 HEAT repeat HEAT_2 PF13646.6 OQR86843.1 - 2.6e-07 30.9 0.2 0.0021 18.4 0.0 4.0 3 1 1 4 4 4 2 HEAT repeats Cnd1 PF12717.7 OQR86843.1 - 5.4e-06 26.5 1.0 0.13 12.3 0.1 3.4 2 2 2 4 4 4 2 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 OQR86843.1 - 7.5e-05 23.1 5.9 0.41 11.2 0.0 6.1 6 0 0 6 6 6 1 HEAT-like repeat Adaptin_N PF01602.20 OQR86843.1 - 0.001 17.7 0.1 3.5 6.1 0.0 3.5 2 1 3 5 5 5 1 Adaptin N terminal region Vac14_Fab1_bd PF12755.7 OQR86843.1 - 0.0033 18.0 0.0 1.1 10.0 0.0 3.8 3 1 0 3 3 3 1 Vacuolar 14 Fab1-binding region MOR2-PAG1_C PF14225.6 OQR86843.1 - 0.0042 17.0 0.3 0.067 13.0 0.0 2.7 2 1 1 3 3 3 1 Cell morphogenesis C-terminal ParcG PF10274.9 OQR86843.1 - 0.031 14.4 0.7 0.44 10.6 0.0 2.7 2 1 1 3 3 3 0 Parkin co-regulated protein CLASP_N PF12348.8 OQR86843.1 - 0.15 11.6 0.1 6.7 6.2 0.0 3.2 3 2 1 4 4 4 0 CLASP N terminal BLM10_mid PF16507.5 OQR86843.1 - 0.34 9.5 0.9 1.1 7.8 0.8 1.7 2 0 0 2 2 2 0 Proteasome-substrate-size regulator, mid region HTH_Tnp_Tc5 PF03221.16 OQR86853.1 - 8.4e-06 25.7 0.0 1.3e-05 25.1 0.0 1.3 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain DDE_3 PF13358.6 OQR86854.1 - 0.05 13.4 0.0 0.063 13.0 0.0 1.1 1 0 0 1 1 1 0 DDE superfamily endonuclease Glyco_hydro_47 PF01532.20 OQR86862.1 - 2.2e-50 171.9 0.0 3.3e-50 171.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 zf-CCCH PF00642.24 OQR86862.1 - 1.2e-37 127.0 40.5 2e-06 27.6 0.9 6.4 6 0 0 6 6 6 6 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RRM_1 PF00076.22 OQR86862.1 - 1.1e-34 118.0 0.3 2.7e-16 59.2 0.1 2.7 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf_CCCH_4 PF18345.1 OQR86862.1 - 1.9e-29 100.8 71.3 9.4e-06 25.5 3.1 6.4 6 0 0 6 6 6 6 Zinc finger domain zf-CCCH_4 PF18044.1 OQR86862.1 - 1.8e-26 91.4 48.4 1.1e-05 25.2 1.7 6.4 6 0 0 6 6 6 6 CCCH-type zinc finger Torus PF16131.5 OQR86862.1 - 1.2e-21 77.4 31.1 0.00017 22.3 0.1 6.8 4 1 2 7 7 7 6 Torus domain zf-CCCH_3 PF15663.5 OQR86862.1 - 3.7e-12 46.4 25.9 0.095 12.9 0.0 6.3 3 2 2 6 6 6 5 Zinc-finger containing family RRM_7 PF16367.5 OQR86862.1 - 5.7e-07 29.6 1.3 0.002 18.2 0.0 3.3 3 0 0 3 3 3 2 RNA recognition motif zf-CCCH_2 PF14608.6 OQR86862.1 - 1.9e-05 24.9 52.9 0.0045 17.4 1.4 6.7 7 0 0 7 7 6 5 RNA-binding, Nab2-type zinc finger Nup35_RRM_2 PF14605.6 OQR86862.1 - 0.013 15.5 0.3 0.49 10.4 0.1 2.4 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif RRM_2 PF04059.12 OQR86862.1 - 0.098 12.9 0.2 14 5.9 0.0 2.4 2 0 0 2 2 2 0 RNA recognition motif 2 NESP55 PF06390.12 OQR86862.1 - 0.52 9.9 9.8 0.061 12.9 0.7 2.4 2 0 0 2 2 2 0 Neuroendocrine-specific golgi protein P55 (NESP55) CDC45 PF02724.14 OQR86862.1 - 1 7.5 8.5 1.7 6.8 8.5 1.2 1 0 0 1 1 1 0 CDC45-like protein RNA_polI_A34 PF08208.11 OQR86862.1 - 4.2 7.4 13.6 0.25 11.4 7.9 1.8 2 0 0 2 2 2 0 DNA-directed RNA polymerase I subunit RPA34.5 PBP1_TM PF14812.6 OQR86862.1 - 10 6.6 9.8 9.4 6.7 3.8 2.7 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal EF-hand_7 PF13499.6 OQR86863.1 - 8.3e-43 144.7 33.0 1.3e-13 51.2 0.7 9.0 8 1 1 9 9 9 6 EF-hand domain pair EF-hand_1 PF00036.32 OQR86863.1 - 2.9e-36 120.3 33.1 1.2e-06 27.6 0.1 11.0 10 0 0 10 10 10 7 EF hand EF-hand_6 PF13405.6 OQR86863.1 - 7.9e-36 118.9 24.9 0.00013 21.7 0.4 11.4 11 0 0 11 11 11 7 EF-hand domain EF-hand_8 PF13833.6 OQR86863.1 - 3.4e-35 119.7 18.6 4.7e-10 39.2 0.1 9.4 8 2 2 10 10 10 5 EF-hand domain pair EF-hand_5 PF13202.6 OQR86863.1 - 1.1e-19 68.9 26.6 0.0034 16.8 0.1 8.4 8 0 0 8 8 8 6 EF hand EF-hand_14 PF17959.1 OQR86863.1 - 4.1e-08 33.5 8.7 0.75 10.2 0.0 7.5 7 3 0 7 7 7 2 EF-hand domain EF-hand_11 PF08976.11 OQR86863.1 - 1.8e-05 25.6 11.3 0.087 13.7 0.0 6.2 7 0 0 7 7 7 1 EF-hand domain SPARC_Ca_bdg PF10591.9 OQR86863.1 - 3.2e-05 24.2 14.9 0.057 13.7 0.2 5.5 5 1 0 5 5 5 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 OQR86863.1 - 0.0064 16.4 8.2 8.6 6.4 0.1 5.7 5 1 0 5 5 5 1 Cytoskeletal-regulatory complex EF hand Tn7_Tnp_TnsA_C PF08721.11 OQR86863.1 - 0.019 15.6 8.9 0.94 10.2 0.1 5.9 5 1 1 6 6 6 0 TnsA endonuclease C terminal EphA2_TM PF14575.6 OQR86863.1 - 0.1 13.5 0.1 0.32 11.9 0.1 1.8 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain UPF0231 PF06062.11 OQR86863.1 - 0.12 12.7 3.5 1.1 9.6 0.2 3.8 4 0 0 4 4 4 0 Uncharacterised protein family (UPF0231) Neil1-DNA_bind PF09292.10 OQR86863.1 - 0.7 9.9 2.9 17 5.5 0.1 3.0 3 0 0 3 3 3 0 Endonuclease VIII-like 1, DNA bind CH_2 PF06294.11 OQR86863.1 - 0.93 9.7 3.6 4.2 7.6 0.1 3.9 4 1 1 5 5 5 0 CH-like domain in sperm protein Pkinase PF00069.25 OQR86864.1 - 2.2e-30 105.9 0.1 2.6e-30 105.7 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQR86864.1 - 1.5e-26 93.3 0.0 2e-26 92.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 OQR86864.1 - 0.00017 21.0 0.6 0.00024 20.5 0.6 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 OQR86864.1 - 0.00036 19.4 0.1 0.00052 18.9 0.1 1.2 1 0 0 1 1 1 1 Fungal protein kinase MULE PF10551.9 OQR86864.1 - 0.0032 17.8 0.1 0.0056 17.1 0.1 1.4 1 0 0 1 1 1 1 MULE transposase domain DUF1356 PF07092.12 OQR86864.1 - 0.034 13.4 0.1 0.052 12.8 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1356) NCBP3 PF10309.9 OQR86864.1 - 0.047 13.5 0.4 0.14 12.1 0.0 2.0 2 0 0 2 2 2 0 Nuclear cap-binding protein subunit 3 Kinase-like PF14531.6 OQR86864.1 - 0.048 13.0 0.0 0.16 11.2 0.0 1.7 2 0 0 2 2 2 0 Kinase-like Sulfotransfer_3 PF13469.6 OQR86918.1 - 1.3e-14 55.1 0.0 3.5e-14 53.7 0.0 1.7 1 0 0 1 1 1 1 Sulfotransferase family Sulfotransfer_1 PF00685.27 OQR86918.1 - 7.4e-11 42.0 0.0 3.5e-10 39.8 0.0 2.0 1 1 0 1 1 1 1 Sulfotransferase domain Asp_Arg_Hydrox PF05118.15 OQR86918.1 - 1.7e-09 37.7 0.0 3.7e-09 36.6 0.0 1.6 1 0 0 1 1 1 1 Aspartyl/Asparaginyl beta-hydroxylase DUF2076 PF09849.9 OQR86920.1 - 0.0045 17.1 4.6 0.0061 16.6 4.6 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2076) Ricin_B_lectin PF00652.22 OQR86945.1 - 0.015 15.5 0.1 0.019 15.2 0.1 1.3 1 1 0 1 1 1 0 Ricin-type beta-trefoil lectin domain Ricin_B_lectin PF00652.22 OQR86946.1 - 1e-20 74.2 12.5 9.8e-14 51.7 5.6 3.0 2 1 1 3 3 3 3 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.6 OQR86946.1 - 4e-10 40.3 7.5 0.00037 21.2 1.8 3.8 2 2 2 4 4 4 3 Ricin-type beta-trefoil lectin domain-like BAG PF02179.16 OQR86976.1 - 6.9e-11 42.4 1.1 1.1e-10 41.8 1.1 1.3 1 0 0 1 1 1 1 BAG domain CRIC_ras_sig PF10534.9 OQR86976.1 - 0.082 13.1 0.0 0.26 11.5 0.0 1.8 1 0 0 1 1 1 0 Connector enhancer of kinase suppressor of ras ThiF PF00899.21 OQR86977.1 - 1.3e-15 57.4 0.0 1.5e-15 57.2 0.0 1.0 1 0 0 1 1 1 1 ThiF family Met_gamma_lyase PF06838.11 OQR86977.1 - 0.073 11.6 0.0 0.088 11.3 0.0 1.0 1 0 0 1 1 1 0 Methionine gamma-lyase TPR_2 PF07719.17 OQR86978.1 - 1.3e-09 37.4 5.2 0.0013 18.7 0.1 6.3 7 1 1 8 8 8 2 Tetratricopeptide repeat TPR_8 PF13181.6 OQR86978.1 - 1.8e-08 33.9 0.0 0.00058 19.9 0.0 4.8 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_14 PF13428.6 OQR86978.1 - 1.2e-07 32.0 2.1 1.1 10.2 0.0 7.0 3 2 3 6 6 6 2 Tetratricopeptide repeat TPR_1 PF00515.28 OQR86978.1 - 2.5e-07 30.2 0.0 0.00028 20.6 0.0 3.9 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 OQR86978.1 - 1.9e-06 28.4 0.0 0.012 16.2 0.0 5.2 6 1 2 8 8 6 3 Tetratricopeptide repeat TPR_12 PF13424.6 OQR86978.1 - 4.7e-05 23.6 0.4 0.0035 17.6 0.0 3.7 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.6 OQR86978.1 - 7.2e-05 22.9 0.0 0.02 15.1 0.0 4.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 OQR86978.1 - 0.0003 21.2 0.3 3.9 8.1 0.0 4.8 3 2 1 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.6 OQR86978.1 - 0.00048 19.8 0.0 0.076 12.7 0.0 3.4 2 1 1 3 3 3 1 TPR repeat ANAPC3 PF12895.7 OQR86978.1 - 0.0092 16.2 0.9 1.6 9.0 0.1 4.3 3 2 2 5 5 5 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.6 OQR86978.1 - 0.018 15.4 0.1 1 9.9 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF4435 PF14491.6 OQR86978.1 - 0.031 14.2 0.1 0.097 12.5 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF4435) TPR_7 PF13176.6 OQR86978.1 - 0.044 13.8 0.8 9.1 6.6 0.0 4.7 4 1 0 4 4 4 0 Tetratricopeptide repeat Sybindin PF04099.12 OQR86979.1 - 3.2e-26 92.0 0.2 3.4e-26 91.9 0.2 1.0 1 0 0 1 1 1 1 Sybindin-like family Sedlin_N PF04628.13 OQR86979.1 - 0.0001 22.4 0.1 0.00011 22.3 0.1 1.1 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Pkinase_Tyr PF07714.17 OQR86980.1 - 5.7e-05 22.5 0.0 7.6e-05 22.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase AP4E_app_platf PF14807.6 OQR86980.1 - 0.15 12.4 0.0 0.95 9.9 0.0 1.9 2 0 0 2 2 2 0 Adaptin AP4 complex epsilon appendage platform TSP_1 PF00090.19 OQR87035.1 - 3.9e-12 46.2 163.1 3e-08 33.7 9.1 15.8 15 2 1 16 16 16 10 Thrombospondin type 1 domain PTN_MK_C PF01091.18 OQR87035.1 - 0.034 14.5 88.2 0.21 12.0 0.2 12.9 11 2 2 13 13 13 0 PTN/MK heparin-binding protein family, C-terminal domain GST_C_6 PF17171.4 OQR87065.1 - 0.18 11.6 0.0 0.4 10.5 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Peptidase_C1 PF00112.23 OQR87091.1 - 1.1e-56 192.4 6.6 1.4e-56 192.0 6.6 1.2 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.15 OQR87091.1 - 0.0035 16.2 0.5 1.2 7.8 0.1 2.2 2 0 0 2 2 2 2 Peptidase C1-like family PT PF04886.12 OQR87091.1 - 3.4 7.3 32.5 2.6e+03 -1.9 32.5 2.6 1 1 0 1 1 1 0 PT repeat DUF659 PF04937.15 OQR87092.1 - 2.4e-05 24.2 1.4 0.05 13.5 0.2 3.3 2 1 1 3 3 3 2 Protein of unknown function (DUF 659) Cu-oxidase_2 PF07731.14 OQR87116.1 - 1e-22 80.4 1.1 1.4e-22 79.9 1.1 1.2 1 0 0 1 1 1 1 Multicopper oxidase Cu-oxidase_3 PF07732.15 OQR87117.1 - 1.7e-05 24.8 0.0 3.1e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 Multicopper oxidase Prefoldin_2 PF01920.20 OQR87118.1 - 3.8e-12 46.1 6.3 4.5e-12 45.8 6.3 1.1 1 0 0 1 1 1 1 Prefoldin subunit DUF5082 PF16888.5 OQR87118.1 - 0.00074 19.8 3.3 0.084 13.2 0.0 2.1 2 0 0 2 2 2 2 Domain of unknown function (DUF5082) DivIC PF04977.15 OQR87118.1 - 0.0011 18.6 7.3 0.086 12.6 0.7 2.8 2 1 1 3 3 3 2 Septum formation initiator GIT_CC PF16559.5 OQR87118.1 - 0.0055 16.6 2.4 1.2 9.1 0.1 2.4 2 0 0 2 2 2 2 GIT coiled-coil Rho guanine nucleotide exchange factor DUF4140 PF13600.6 OQR87118.1 - 0.012 16.0 6.3 0.74 10.3 0.8 2.1 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) DUF3847 PF12958.7 OQR87118.1 - 0.015 15.4 5.5 0.054 13.6 3.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3847) FlaC_arch PF05377.11 OQR87118.1 - 0.19 12.1 3.7 0.24 11.8 0.2 2.2 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) V_ATPase_I PF01496.19 OQR87118.1 - 0.28 9.0 3.2 0.31 8.9 3.2 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family APG6_N PF17675.1 OQR87118.1 - 7.4 7.1 13.8 2.3 8.7 0.9 2.0 1 1 0 2 2 2 0 Apg6 coiled-coil region P5CR_dimer PF14748.6 OQR87119.1 - 1.4e-35 121.6 0.5 2.6e-35 120.8 0.5 1.4 1 0 0 1 1 1 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.17 OQR87119.1 - 1e-18 67.7 0.3 1.9e-18 66.8 0.3 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.15 OQR87119.1 - 1.6e-05 25.1 0.1 3.3e-05 24.1 0.1 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 3HCDH_N PF02737.18 OQR87119.1 - 5.2e-05 23.2 0.2 5.2e-05 23.2 0.2 2.1 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.23 OQR87119.1 - 5.2e-05 23.3 0.2 0.0011 19.0 0.1 2.3 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus ApbA PF02558.16 OQR87119.1 - 0.00028 20.5 0.0 0.00041 20.0 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Shikimate_DH PF01488.20 OQR87119.1 - 0.0016 18.5 0.3 0.0044 17.1 0.3 1.7 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase UDPG_MGDP_dh_C PF03720.15 OQR87119.1 - 0.0017 18.7 0.0 0.0034 17.8 0.0 1.4 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain OCD_Mu_crystall PF02423.15 OQR87119.1 - 0.019 13.9 0.1 0.042 12.8 0.1 1.6 1 0 0 1 1 1 0 Ornithine cyclodeaminase/mu-crystallin family GFO_IDH_MocA PF01408.22 OQR87119.1 - 0.024 15.4 0.0 1.3 9.8 0.0 2.4 1 1 1 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_7 PF13241.6 OQR87119.1 - 0.027 14.9 0.0 0.058 13.8 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding CoA_binding PF02629.19 OQR87119.1 - 0.063 14.0 0.5 0.15 12.8 0.5 1.7 1 0 0 1 1 1 0 CoA binding domain PSDC PF12588.8 OQR87130.1 - 0.059 13.3 0.1 0.097 12.6 0.1 1.3 1 0 0 1 1 1 0 Phophatidylserine decarboxylase p450 PF00067.22 OQR87134.1 - 0.028 13.2 0.0 0.33 9.7 0.0 2.1 2 0 0 2 2 2 0 Cytochrome P450 UL2 PF08196.11 OQR87134.1 - 0.086 12.8 0.0 0.17 11.8 0.0 1.5 1 0 0 1 1 1 0 UL2 protein HAD_SAK_2 PF18143.1 OQR87146.1 - 0.033 14.5 0.0 0.05 13.9 0.0 1.3 1 1 0 1 1 1 0 HAD domain in Swiss Army Knife RNA repair proteins Lipocalin_3 PF12702.7 OQR87146.1 - 0.099 12.7 0.1 0.14 12.3 0.1 1.3 1 0 0 1 1 1 0 Lipocalin-like Mito_carr PF00153.27 OQR87168.1 - 1.4e-54 182.0 1.2 6.4e-23 80.5 0.0 3.5 3 1 0 3 3 3 3 Mitochondrial carrier protein PfkB PF00294.24 OQR87168.1 - 3.3e-24 85.7 0.0 6.8e-24 84.7 0.0 1.4 1 1 0 1 1 1 1 pfkB family carbohydrate kinase ADP_PFK_GK PF04587.15 OQR87168.1 - 0.067 11.8 0.0 0.11 11.1 0.0 1.3 1 0 0 1 1 1 0 ADP-specific Phosphofructokinase/Glucokinase conserved region NOD2_WH PF17779.1 OQR87168.1 - 0.32 11.4 1.8 39 4.7 0.4 3.5 3 0 0 3 3 3 0 NOD2 winged helix domain ABC_membrane PF00664.23 OQR87169.1 - 2.7e-79 266.7 38.9 1.6e-41 142.8 15.6 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 OQR87169.1 - 1.7e-52 177.6 0.1 1.2e-29 103.5 0.0 3.0 4 0 0 4 4 2 2 ABC transporter SMC_N PF02463.19 OQR87169.1 - 3.3e-06 26.7 8.0 0.075 12.5 0.1 4.1 2 2 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 OQR87169.1 - 4.8e-05 23.0 0.2 0.26 11.0 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 OQR87169.1 - 6.4e-05 22.9 0.1 0.066 13.1 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 OQR87169.1 - 7.8e-05 22.7 2.1 0.36 10.9 0.2 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_16 PF13191.6 OQR87169.1 - 0.00079 19.8 0.0 0.66 10.3 0.0 2.9 2 0 0 2 2 2 1 AAA ATPase domain DUF87 PF01935.17 OQR87169.1 - 0.0016 18.6 1.5 0.72 9.9 0.1 2.4 2 0 0 2 2 2 2 Helicase HerA, central domain AAA_21 PF13304.6 OQR87169.1 - 0.0061 16.4 1.0 3.5 7.4 0.0 3.5 3 1 0 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system MeaB PF03308.16 OQR87169.1 - 0.012 14.6 0.8 6.7 5.6 0.0 3.1 3 0 0 3 3 3 0 Methylmalonyl Co-A mutase-associated GTPase MeaB TsaE PF02367.17 OQR87169.1 - 0.024 14.6 0.3 2.2 8.3 0.0 3.1 2 1 0 3 3 3 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE cobW PF02492.19 OQR87169.1 - 0.032 13.8 1.0 2 8.0 0.1 3.1 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain Dynamin_N PF00350.23 OQR87169.1 - 0.06 13.4 6.0 0.73 9.9 1.0 2.6 2 0 0 2 2 2 0 Dynamin family Roc PF08477.13 OQR87169.1 - 0.07 13.3 1.0 3.2 8.0 0.1 3.2 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase FtsK_SpoIIIE PF01580.18 OQR87169.1 - 0.072 12.4 0.3 8.6 5.6 0.1 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family NACHT PF05729.12 OQR87169.1 - 0.11 12.4 4.9 1.9 8.4 0.1 3.9 4 0 0 4 4 4 0 NACHT domain T2SSE PF00437.20 OQR87169.1 - 0.13 11.3 0.1 6.5 5.7 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_23 PF13476.6 OQR87169.1 - 0.17 12.3 0.0 31 5.0 0.0 2.5 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.22 OQR87169.1 - 0.2 10.8 2.9 2 7.5 0.1 2.7 3 0 0 3 3 3 0 NB-ARC domain ATP_bind_1 PF03029.17 OQR87169.1 - 0.99 9.1 4.0 6.8 6.4 0.5 2.8 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein AAA_33 PF13671.6 OQR87169.1 - 2.3 8.4 4.5 1.8 8.7 0.3 2.7 3 0 0 3 3 3 0 AAA domain AAA_22 PF13401.6 OQR87169.1 - 2.8 8.2 7.0 11 6.2 0.4 3.4 4 0 0 4 4 4 0 AAA domain DUF676 PF05057.14 OQR87170.1 - 5e-33 114.4 0.0 7.6e-33 113.9 0.0 1.1 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Palm_thioest PF02089.15 OQR87170.1 - 0.00014 21.8 0.0 0.00021 21.2 0.0 1.3 1 0 0 1 1 1 1 Palmitoyl protein thioesterase PGAP1 PF07819.13 OQR87170.1 - 0.0013 18.5 0.1 0.0029 17.4 0.1 1.6 1 1 0 1 1 1 1 PGAP1-like protein Lipase_3 PF01764.25 OQR87170.1 - 0.015 15.2 0.0 0.033 14.1 0.0 1.6 1 0 0 1 1 1 0 Lipase (class 3) Tubulin PF00091.25 OQR87170.1 - 0.026 14.7 0.0 0.046 13.9 0.0 1.4 1 0 0 1 1 1 0 Tubulin/FtsZ family, GTPase domain LCAT PF02450.15 OQR87170.1 - 0.029 13.6 0.0 0.052 12.7 0.0 1.3 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase Abhydrolase_6 PF12697.7 OQR87170.1 - 0.041 14.5 0.0 0.053 14.1 0.0 1.3 1 1 0 1 1 1 0 Alpha/beta hydrolase family Ricin_B_lectin PF00652.22 OQR87193.1 - 1.9e-21 76.6 4.0 1.7e-12 47.7 0.5 2.1 2 0 0 2 2 2 2 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.6 OQR87193.1 - 3.3e-07 30.9 7.9 0.00038 21.1 0.4 3.5 2 2 2 4 4 4 3 Ricin-type beta-trefoil lectin domain-like CDtoxinA PF03498.14 OQR87193.1 - 0.0072 15.9 2.4 0.034 13.7 0.1 2.5 1 1 1 3 3 3 1 Cytolethal distending toxin A/C domain Peptidase_M14 PF00246.24 OQR87200.1 - 1.5e-45 156.2 0.2 2.3e-45 155.6 0.2 1.2 1 0 0 1 1 1 1 Zinc carboxypeptidase Glyco_hydro_16 PF00722.21 OQR87200.1 - 9.2e-08 31.8 0.0 1.8e-07 30.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Ank_2 PF12796.7 OQR87206.1 - 1.7e-22 79.8 15.7 1.1e-06 29.2 0.2 7.0 5 2 3 8 8 8 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQR87206.1 - 6.9e-16 58.4 10.3 0.00024 21.6 0.2 8.6 9 1 0 9 9 9 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 OQR87206.1 - 2.6e-15 56.3 13.3 0.048 14.0 0.0 10.1 5 3 6 11 11 11 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQR87206.1 - 2e-13 49.2 19.6 1.8 9.4 0.0 13.3 13 2 2 15 15 15 2 Ankyrin repeat Trans_reg_C PF00486.28 OQR87206.1 - 0.012 15.7 0.0 28 4.9 0.0 4.2 3 1 1 4 4 4 0 Transcriptional regulatory protein, C terminal Baculo_LEF5_C PF11792.8 OQR87206.1 - 0.025 14.2 0.1 9.6 6.0 0.1 2.6 2 0 0 2 2 2 0 Baculoviridae late expression factor 5 C-terminal domain HTH_11 PF08279.12 OQR87206.1 - 0.052 13.5 0.0 21 5.1 0.0 3.9 4 0 0 4 4 4 0 HTH domain Ank PF00023.30 OQR87206.1 - 0.066 13.7 7.4 63 4.3 0.3 7.2 6 2 1 7 7 7 0 Ankyrin repeat Ank_2 PF12796.7 OQR87207.1 - 1.2e-08 35.4 1.8 9.3e-07 29.4 1.2 2.6 2 1 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OQR87207.1 - 2.5e-06 27.6 0.6 0.29 11.5 0.0 3.6 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 OQR87207.1 - 1.2e-05 25.8 2.5 0.033 14.8 0.5 3.6 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQR87207.1 - 1.7e-05 24.8 0.5 0.56 10.9 0.0 4.3 5 0 0 5 5 5 2 Ankyrin repeat Ank PF00023.30 OQR87207.1 - 0.0054 17.1 0.3 5.5 7.6 0.0 4.0 4 0 0 4 4 4 1 Ankyrin repeat Ank_2 PF12796.7 OQR87208.1 - 9.8e-11 42.1 3.1 0.00096 19.7 0.1 4.1 3 1 1 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQR87208.1 - 6.4e-08 33.0 1.2 0.0021 18.6 0.1 3.5 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQR87208.1 - 3.8e-05 23.8 0.3 29 5.7 0.0 5.7 4 1 1 5 5 5 1 Ankyrin repeat DUF5049 PF16468.5 OQR87208.1 - 0.00022 21.0 2.9 0.41 10.6 0.0 4.4 4 1 1 5 5 5 1 Domain of unknown function (DUF5049) Ank_5 PF13857.6 OQR87208.1 - 0.002 18.4 1.3 2.1 8.8 0.0 3.8 2 2 2 4 4 4 1 Ankyrin repeats (many copies) Bin3 PF06859.12 OQR87209.1 - 8.1e-20 71.5 0.1 1.4e-19 70.7 0.1 1.4 1 0 0 1 1 1 1 Bicoid-interacting protein 3 (Bin3) dsrm PF00035.26 OQR87209.1 - 1.2e-10 42.0 0.0 2.4e-10 41.0 0.0 1.5 1 0 0 1 1 1 1 Double-stranded RNA binding motif Methyltransf_31 PF13847.6 OQR87209.1 - 7e-07 29.2 0.0 0.0024 17.7 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_25 PF13649.6 OQR87209.1 - 0.00041 21.0 0.0 0.085 13.6 0.0 2.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 OQR87209.1 - 0.066 14.0 0.2 19 6.1 0.0 2.8 3 0 0 3 3 3 0 Methyltransferase domain PRA1 PF03208.19 OQR87218.1 - 1.1e-20 73.7 0.6 1.5e-20 73.3 0.6 1.1 1 0 0 1 1 1 1 PRA1 family protein YIEGIA PF14045.6 OQR87218.1 - 0.028 13.3 0.0 0.039 12.8 0.0 1.2 1 0 0 1 1 1 0 YIEGIA protein Ion_trans PF00520.31 OQR87250.1 - 0.0002 20.7 51.5 0.00076 18.8 22.5 3.5 2 2 1 3 3 3 2 Ion transport protein HycH PF07450.11 OQR87250.1 - 0.017 15.5 0.2 2.6 8.4 0.0 2.8 3 0 0 3 3 3 0 Formate hydrogenlyase maturation protein HycH Baculo_PEP_C PF04513.12 OQR87250.1 - 0.047 13.7 0.4 0.1 12.6 0.4 1.5 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Bacillus_HBL PF05791.11 OQR87250.1 - 0.13 12.1 0.5 0.23 11.3 0.5 1.4 1 0 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) Adap_comp_sub PF00928.21 OQR87251.1 - 3.2e-69 233.2 0.0 3.9e-69 233.0 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 OQR87251.1 - 0.00083 19.3 0.0 0.0014 18.6 0.0 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain TniB PF05621.11 OQR87251.1 - 0.16 11.4 0.0 0.28 10.6 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein Enolase_C PF00113.22 OQR87256.1 - 5.6e-149 495.2 0.1 7e-149 494.9 0.1 1.1 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.16 OQR87256.1 - 2.2e-57 192.9 0.0 3.8e-57 192.1 0.0 1.4 1 0 0 1 1 1 1 Enolase, N-terminal domain MR_MLE_C PF13378.6 OQR87256.1 - 7.7e-08 32.2 0.0 1.2e-07 31.5 0.0 1.3 1 0 0 1 1 1 1 Enolase C-terminal domain-like MAAL_C PF07476.11 OQR87256.1 - 1.3e-06 27.7 0.1 3.2e-06 26.5 0.1 1.6 2 0 0 2 2 2 1 Methylaspartate ammonia-lyase C-terminus Fibin PF15819.5 OQR87258.1 - 0.0035 17.1 0.6 0.0073 16.1 0.6 1.5 1 0 0 1 1 1 1 Fin bud initiation factor homologue Kinesin_assoc PF16183.5 OQR87275.1 - 2 8.5 8.5 2.9 8.0 8.5 1.4 1 1 0 1 1 1 0 Kinesin-associated VPS11_C PF12451.8 OQR87275.1 - 2.7 8.3 7.7 1.3 9.3 1.3 2.4 2 0 0 2 2 2 0 Vacuolar protein sorting protein 11 C terminal CENP-O PF09496.10 OQR87276.1 - 0.0097 15.9 1.5 0.012 15.6 1.5 1.1 1 0 0 1 1 1 1 Cenp-O kinetochore centromere component bZIP_2 PF07716.15 OQR87276.1 - 0.035 14.2 5.3 0.035 14.2 5.3 2.4 2 0 0 2 2 2 0 Basic region leucine zipper bPH_3 PF14470.6 OQR87276.1 - 0.1 13.0 1.0 0.72 10.2 0.0 2.3 2 1 0 2 2 2 0 Bacterial PH domain HU-DNA_bdg PF14848.6 OQR87295.1 - 0.14 12.1 0.0 0.15 12.1 0.0 1.1 1 0 0 1 1 1 0 DNA-binding domain Pkinase PF00069.25 OQR87296.1 - 9.7e-73 244.8 0.1 1.2e-72 244.5 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQR87296.1 - 1e-31 110.2 0.0 1.3e-31 109.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OQR87296.1 - 2.9e-10 39.9 0.0 4.8e-07 29.4 0.0 2.1 2 0 0 2 2 2 2 Kinase-like Pkinase_fungal PF17667.1 OQR87296.1 - 0.00022 20.1 0.0 0.00036 19.4 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase FTA2 PF13095.6 OQR87296.1 - 0.00091 18.9 0.2 1.3 8.5 0.0 2.6 3 0 0 3 3 3 2 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 OQR87296.1 - 0.0016 17.9 0.7 0.004 16.5 0.1 1.8 1 1 1 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OQR87296.1 - 0.0018 18.2 0.2 0.019 14.9 0.2 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 OQR87296.1 - 0.074 12.6 0.2 0.14 11.8 0.2 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase Plant_tran PF04827.14 OQR87297.1 - 4.9e-18 65.5 0.0 5.2e-18 65.4 0.0 1.0 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_4 PF13359.6 OQR87297.1 - 0.062 13.0 0.0 0.07 12.8 0.0 1.1 1 0 0 1 1 1 0 DDE superfamily endonuclease HCNGP PF07818.13 OQR87298.1 - 3.1e-20 72.6 0.1 6.4e-20 71.6 0.1 1.5 1 0 0 1 1 1 1 HCNGP-like protein RCC1 PF00415.18 OQR87299.1 - 3.1e-74 245.4 19.5 1.5e-11 44.7 0.3 7.2 7 0 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 OQR87299.1 - 6.1e-26 89.6 44.4 5.4e-07 29.2 2.7 8.3 8 1 0 8 8 8 7 Regulator of chromosome condensation (RCC1) repeat SAP PF02037.27 OQR87299.1 - 0.00027 20.6 0.0 0.00064 19.4 0.0 1.7 1 0 0 1 1 1 1 SAP domain Ribosomal_L16 PF00252.18 OQR87299.1 - 0.029 14.4 0.2 0.078 13.0 0.0 1.7 2 0 0 2 2 2 0 Ribosomal protein L16p/L10e GGDEF_2 PF17853.1 OQR87299.1 - 0.052 13.8 0.0 0.11 12.7 0.0 1.5 1 0 0 1 1 1 0 GGDEF-like domain SelR PF01641.18 OQR87333.1 - 1.1e-49 167.5 0.2 1.2e-49 167.4 0.2 1.0 1 0 0 1 1 1 1 SelR domain GFA PF04828.14 OQR87333.1 - 0.028 14.8 0.6 0.55 10.6 0.1 2.1 1 1 0 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme zinc_ribbon_10 PF10058.9 OQR87333.1 - 0.044 13.5 0.6 1.2 9.0 0.0 2.2 2 0 0 2 2 2 0 Predicted integral membrane zinc-ribbon metal-binding protein Ribosomal_L37e PF01907.19 OQR87333.1 - 0.21 11.8 4.3 7.8 6.7 0.1 2.4 2 0 0 2 2 2 0 Ribosomal protein L37e Auto_anti-p27 PF06677.12 OQR87333.1 - 0.31 11.2 2.1 6.4 7.0 0.1 2.8 3 0 0 3 3 3 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) Ku_PK_bind PF08785.11 OQR87334.1 - 0.12 12.5 0.0 0.3 11.2 0.0 1.7 1 0 0 1 1 1 0 Ku C terminal domain like Mad3_BUB1_I PF08311.12 OQR87335.1 - 3.4e-40 136.9 0.7 6e-40 136.1 0.7 1.4 1 0 0 1 1 1 1 Mad3/BUB1 homology region 1 Mad3_BUB1_I_2 PF17014.5 OQR87335.1 - 8.4e-05 22.7 0.2 0.00018 21.6 0.2 1.5 1 0 0 1 1 1 1 Putative Mad3/BUB1 like region 1 protein adh_short PF00106.25 OQR87358.1 - 1.1e-44 152.3 0.6 1.2e-44 152.1 0.6 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OQR87358.1 - 7.6e-42 143.5 0.2 8.9e-42 143.2 0.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OQR87358.1 - 8.1e-09 35.6 0.4 1.6e-08 34.6 0.4 1.4 1 1 0 1 1 1 1 KR domain DUF1776 PF08643.10 OQR87358.1 - 0.0027 17.2 0.0 0.0061 16.0 0.0 1.6 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) IHHNV_capsid PF16530.5 OQR87359.1 - 0.11 11.6 0.0 0.17 11.0 0.0 1.2 1 0 0 1 1 1 0 Infectious hypodermal and haematopoietic necrosis virus, capsid Branch_AA_trans PF05525.13 OQR87359.1 - 0.17 10.7 0.0 0.21 10.4 0.0 1.1 1 0 0 1 1 1 0 Branched-chain amino acid transport protein Aldo_ket_red PF00248.21 OQR87360.1 - 5.6e-73 245.7 0.0 6.4e-73 245.5 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Hydrolase PF00702.26 OQR87360.1 - 0.044 14.1 0.0 0.66 10.2 0.0 2.5 1 1 0 2 2 2 0 haloacid dehalogenase-like hydrolase p25-alpha PF05517.12 OQR87377.1 - 2.9e-05 24.3 0.3 0.019 15.1 0.1 3.0 3 1 0 3 3 3 2 p25-alpha DUF535 PF04393.13 OQR87377.1 - 0.047 12.9 0.0 0.15 11.3 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF535) Pkinase_Tyr PF07714.17 OQR87378.1 - 2e-52 178.0 0.0 4.6e-52 176.9 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.25 OQR87378.1 - 4e-51 173.9 0.0 5.7e-51 173.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Crystall PF00030.19 OQR87378.1 - 6.6e-09 35.8 0.5 3.6e-05 23.9 0.0 2.5 2 0 0 2 2 2 2 Beta/Gamma crystallin Kdo PF06293.14 OQR87378.1 - 2.2e-05 23.9 0.1 3.9e-05 23.1 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 OQR87378.1 - 2.9e-05 23.0 0.0 5.8e-05 22.0 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 OQR87378.1 - 0.0045 16.9 0.0 0.0078 16.2 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 OQR87378.1 - 0.017 14.4 0.0 0.042 13.2 0.0 1.6 2 0 0 2 2 2 0 Kinase-like Haspin_kinase PF12330.8 OQR87378.1 - 0.033 13.1 0.0 0.095 11.6 0.1 1.7 1 1 0 1 1 1 0 Haspin like kinase domain FTA2 PF13095.6 OQR87378.1 - 0.15 11.6 0.0 0.44 10.1 0.0 1.7 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Inhibitor_I36 PF03995.13 OQR87378.1 - 1.5 8.8 4.8 30 4.6 0.1 3.3 3 1 1 4 4 4 0 Peptidase inhibitor family I36 SMC_N PF02463.19 OQR87379.1 - 0.0047 16.4 0.2 0.0076 15.7 0.2 1.3 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain SbcCD_C PF13558.6 OQR87379.1 - 0.15 12.3 1.2 0.27 11.5 0.1 1.9 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit WD40 PF00400.32 OQR87381.1 - 2.7e-10 40.7 10.0 0.019 15.8 0.0 5.1 6 0 0 6 6 6 4 WD domain, G-beta repeat NADHdh PF00146.21 OQR87384.1 - 5.5e-26 91.6 2.0 6.1e-26 91.4 1.3 1.5 1 1 0 1 1 1 1 NADH dehydrogenase ATP-synt_C PF00137.21 OQR87384.1 - 0.3 11.5 10.9 0.3 11.4 8.4 2.2 2 1 0 2 2 2 0 ATP synthase subunit C BTB_2 PF02214.22 OQR87385.1 - 2.1e-15 56.8 0.0 5.2e-15 55.6 0.0 1.6 2 0 0 2 2 2 1 BTB/POZ domain AMP-binding PF00501.28 OQR87397.1 - 9e-53 179.4 0.0 1.1e-52 179.0 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 OQR87397.1 - 0.034 15.1 0.0 0.081 13.9 0.0 1.7 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain DLIC PF05783.11 OQR87399.1 - 2.2e-15 56.4 0.0 9.4e-10 37.9 0.0 2.1 1 1 1 2 2 2 2 Dynein light intermediate chain (DLIC) Roc PF08477.13 OQR87399.1 - 4.5e-06 26.9 0.0 1.6e-05 25.1 0.0 2.0 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 OQR87399.1 - 0.004 16.8 0.0 0.01 15.4 0.0 1.7 2 0 0 2 2 2 1 Ras family AAA_16 PF13191.6 OQR87399.1 - 0.067 13.6 0.0 0.15 12.4 0.0 1.8 1 1 0 1 1 1 0 AAA ATPase domain RIIa PF02197.17 OQR87400.1 - 0.054 13.2 0.0 0.083 12.6 0.0 1.4 1 0 0 1 1 1 0 Regulatory subunit of type II PKA R-subunit MHB PF16525.5 OQR87400.1 - 0.18 12.1 0.0 0.22 11.8 0.0 1.2 1 0 0 1 1 1 0 Haemophore, haem-binding RdRP PF05183.12 OQR87423.1 - 3.5e-148 494.9 0.0 4.9e-148 494.4 0.0 1.2 1 0 0 1 1 1 1 RNA dependent RNA polymerase tRNA-synt_His PF13393.6 OQR87423.1 - 0.089 12.0 0.0 0.14 11.4 0.0 1.2 1 0 0 1 1 1 0 Histidyl-tRNA synthetase Trypsin_2 PF13365.6 OQR87424.1 - 1.8e-12 48.4 0.2 3.3e-12 47.6 0.2 1.4 1 0 0 1 1 1 1 Trypsin-like peptidase domain Trypsin PF00089.26 OQR87424.1 - 0.00015 21.6 2.9 0.00036 20.4 2.9 1.6 1 1 0 1 1 1 1 Trypsin Peptidase_S46 PF10459.9 OQR87424.1 - 0.091 11.4 0.1 0.19 10.3 0.1 1.4 1 0 0 1 1 1 0 Peptidase S46 Trypan_PARP PF05887.11 OQR87424.1 - 4 7.4 24.9 9.1 6.3 24.9 1.5 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Ricin_B_lectin PF00652.22 OQR87425.1 - 4.4e-10 39.9 11.6 1.3e-06 28.6 5.1 3.1 2 1 0 3 3 3 3 Ricin-type beta-trefoil lectin domain DEC-1_N PF04625.13 OQR87425.1 - 2 7.4 5.7 2.5 7.0 5.7 1.2 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region BPD_transp_1 PF00528.22 OQR87448.1 - 0.00012 21.9 1.5 0.00012 21.9 1.5 1.9 2 0 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component Ank_2 PF12796.7 OQR87449.1 - 3.1e-99 325.7 36.4 1.5e-18 67.1 2.7 10.8 5 3 6 11 11 11 11 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQR87449.1 - 2.2e-75 248.1 24.5 1.2e-11 44.9 0.1 15.6 5 4 12 17 17 17 14 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQR87449.1 - 1.6e-68 218.5 22.0 0.00029 21.0 0.0 18.9 20 0 0 20 20 20 14 Ankyrin repeat Ank_5 PF13857.6 OQR87449.1 - 4.1e-63 208.6 35.7 3.3e-09 36.8 1.2 15.4 8 5 8 16 16 16 14 Ankyrin repeats (many copies) Ank PF00023.30 OQR87449.1 - 1.5e-59 195.9 42.3 0.00016 22.0 0.0 19.8 20 0 0 20 20 20 12 Ankyrin repeat PEGA PF08308.11 OQR87449.1 - 0.0014 18.5 4.6 1.5 8.7 0.0 6.1 8 1 1 9 9 9 1 PEGA domain DUF2170 PF09938.9 OQR87449.1 - 0.0062 16.2 0.8 48 3.7 0.0 4.8 4 1 1 5 5 5 0 Uncharacterized protein conserved in bacteria (DUF2170) PhnH PF05845.12 OQR87449.1 - 0.022 14.5 0.0 0.057 13.2 0.0 1.6 1 0 0 1 1 1 0 Bacterial phosphonate metabolism protein (PhnH) DUF4988 PF16378.5 OQR87449.1 - 0.024 14.3 0.7 4.7 6.8 0.0 4.2 4 0 0 4 4 4 0 Domain of unknown function YlzJ PF14035.6 OQR87449.1 - 0.082 13.1 0.0 0.95 9.7 0.0 2.8 2 0 0 2 2 2 0 YlzJ-like protein PTR2 PF00854.21 OQR87477.1 - 4.6e-49 167.3 2.6 8.4e-49 166.4 2.6 1.4 1 1 0 1 1 1 1 POT family MFS_1 PF07690.16 OQR87477.1 - 5.7e-08 32.1 18.0 2.9e-07 29.8 17.3 2.0 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF4293 PF14126.6 OQR87477.1 - 0.052 13.8 2.2 0.062 13.5 0.6 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4293) TMEM43 PF07787.12 OQR87501.1 - 2.2 7.6 11.1 4.2e+02 0.1 11.1 2.3 1 1 0 1 1 1 0 Transmembrane protein 43 RCC1 PF00415.18 OQR87502.1 - 5.6e-61 203.0 3.6 1.6e-13 51.0 0.2 6.5 6 0 0 6 6 6 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 OQR87502.1 - 3e-40 135.2 20.7 9.7e-09 34.8 1.4 6.4 6 0 0 6 6 6 5 Regulator of chromosome condensation (RCC1) repeat TIG PF01833.24 OQR87502.1 - 6.5e-12 45.4 2.4 0.0013 18.8 0.5 5.1 4 1 0 4 4 4 3 IPT/TIG domain Trypsin_2 PF13365.6 OQR87503.1 - 7.8e-15 56.1 0.1 1.3e-14 55.4 0.1 1.3 1 0 0 1 1 1 1 Trypsin-like peptidase domain Trypsin PF00089.26 OQR87503.1 - 0.00033 20.5 3.2 0.0014 18.5 2.2 2.3 2 1 0 2 2 2 1 Trypsin Peptidase_S46 PF10459.9 OQR87503.1 - 0.1 11.2 1.2 4.1 5.9 0.1 2.1 2 0 0 2 2 2 0 Peptidase S46 AAA_6 PF12774.7 OQR87505.1 - 8.4e-149 495.0 0.4 4.2e-147 489.4 0.0 3.0 3 0 0 3 3 3 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 OQR87505.1 - 4.7e-131 437.6 2.0 4.7e-131 437.6 2.0 3.3 3 0 0 3 3 3 1 Dynein heavy chain, N-terminal region 2 AAA_8 PF12780.7 OQR87505.1 - 8.4e-104 346.5 0.0 2.5e-103 344.9 0.0 1.9 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 AAA_9 PF12781.7 OQR87505.1 - 4.4e-85 284.3 0.3 4.4e-85 284.3 0.3 4.3 5 0 0 5 5 5 1 ATP-binding dynein motor region AAA_7 PF12775.7 OQR87505.1 - 4.9e-70 234.7 0.7 1.1e-65 220.6 0.0 4.3 4 0 0 4 4 4 1 P-loop containing dynein motor region MT PF12777.7 OQR87505.1 - 3.4e-50 171.0 18.2 8.1e-50 169.8 18.2 1.6 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_5 PF07728.14 OQR87505.1 - 4.1e-13 49.5 0.4 0.057 13.4 0.0 6.4 6 1 0 6 6 5 3 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 OQR87505.1 - 5.1e-10 39.8 1.0 0.024 14.9 0.0 6.4 7 0 0 7 7 5 2 AAA domain AAA PF00004.29 OQR87505.1 - 1.2e-08 35.5 3.6 0.28 11.6 0.0 6.0 6 0 0 6 6 6 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 OQR87505.1 - 2.5e-08 34.5 0.0 0.095 13.1 0.0 5.3 4 0 0 4 4 4 1 AAA ATPase domain ResIII PF04851.15 OQR87505.1 - 2.4e-06 27.7 0.9 0.013 15.5 0.3 3.0 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit AAA_18 PF13238.6 OQR87505.1 - 7.2e-06 26.6 5.0 0.016 15.8 0.0 5.5 6 0 0 6 6 4 1 AAA domain ABC_tran PF00005.27 OQR87505.1 - 0.00021 21.8 0.3 1.7 9.2 0.0 4.6 5 0 0 5 5 3 1 ABC transporter Dynein_AAA_lid PF17852.1 OQR87505.1 - 0.00025 21.1 0.5 1.3 9.1 0.0 3.7 2 1 1 3 3 2 2 Dynein heavy chain AAA lid domain RNA_helicase PF00910.22 OQR87505.1 - 0.00042 20.7 0.1 4.9 7.6 0.0 3.9 3 0 0 3 3 3 1 RNA helicase DUF2075 PF09848.9 OQR87505.1 - 0.00064 19.1 0.0 0.002 17.4 0.0 1.8 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_33 PF13671.6 OQR87505.1 - 0.0024 18.1 0.8 13 5.9 0.0 4.4 4 0 0 4 4 4 0 AAA domain AAA_30 PF13604.6 OQR87505.1 - 0.0033 17.2 7.1 2.9 7.6 0.0 4.3 5 0 0 5 5 3 1 AAA domain AAA_19 PF13245.6 OQR87505.1 - 0.0034 17.7 3.1 0.057 13.8 0.1 3.8 3 0 0 3 3 3 1 AAA domain AAA_14 PF13173.6 OQR87505.1 - 0.0042 17.1 0.3 0.26 11.3 0.0 3.3 3 0 0 3 3 3 1 AAA domain AAA_lid_1 PF17857.1 OQR87505.1 - 0.0065 16.7 1.0 0.1 12.8 0.0 3.3 3 0 0 3 3 3 1 AAA+ lid domain Dynein_heavy PF03028.15 OQR87505.1 - 0.0094 16.0 0.4 0.23 11.6 0.0 3.4 4 0 0 4 4 2 1 Dynein heavy chain region D6 P-loop domain NACHT PF05729.12 OQR87505.1 - 0.031 14.2 1.8 11 5.9 0.0 4.0 4 0 0 4 4 4 0 NACHT domain AAA_29 PF13555.6 OQR87505.1 - 0.034 13.9 0.7 19 5.1 0.0 3.6 3 0 0 3 3 3 0 P-loop containing region of AAA domain TsaE PF02367.17 OQR87505.1 - 0.045 13.8 2.6 7.7 6.5 0.0 3.6 3 0 0 3 3 3 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE T2SSE PF00437.20 OQR87505.1 - 0.078 12.0 6.1 2.4 7.1 0.1 4.2 5 0 0 5 5 4 0 Type II/IV secretion system protein KH_2 PF07650.17 OQR87505.1 - 0.096 12.5 0.2 0.41 10.5 0.2 2.1 1 0 0 1 1 1 0 KH domain AAA_28 PF13521.6 OQR87505.1 - 0.16 12.2 0.4 99 3.1 0.0 3.9 4 0 0 4 4 3 0 AAA domain M PF02370.16 OQR87505.1 - 0.44 11.3 5.5 2.4 9.0 2.6 3.7 2 0 0 2 2 2 0 M protein repeat Mg_chelatase PF01078.21 OQR87505.1 - 0.58 9.5 3.4 10 5.4 0.0 3.5 4 0 0 4 4 3 0 Magnesium chelatase, subunit ChlI Sec8_exocyst PF04048.14 OQR87505.1 - 7.4 6.5 11.6 0.27 11.1 0.8 3.9 4 0 0 4 4 4 0 Sec8 exocyst complex component specific domain MFS_1 PF07690.16 OQR87520.1 - 1.6e-20 73.4 13.8 1.8e-20 73.2 13.8 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily OATP PF03137.20 OQR87520.1 - 5.6e-12 44.7 3.7 5.6e-12 44.7 3.7 3.0 1 1 1 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family Sugar_tr PF00083.24 OQR87520.1 - 1.1e-07 31.1 12.9 1.8e-07 30.4 12.9 1.5 1 1 0 1 1 1 1 Sugar (and other) transporter RQC PF09382.10 OQR87521.1 - 0.13 12.0 0.0 0.18 11.6 0.0 1.3 1 0 0 1 1 1 0 RQC domain WD40_4 PF16300.5 OQR87535.1 - 1.2e-32 111.6 0.9 1.1e-16 60.4 0.1 2.8 2 0 0 2 2 2 2 Type of WD40 repeat WD40 PF00400.32 OQR87535.1 - 9.5e-22 76.9 7.1 3.3e-08 34.0 0.0 7.3 8 0 0 8 8 8 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OQR87535.1 - 6.9e-15 55.1 0.4 5.5e-05 23.4 0.1 5.1 2 2 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain DUF1899 PF08953.11 OQR87535.1 - 1.8e-06 27.7 0.0 0.002 18.0 0.0 2.7 2 0 0 2 2 2 2 Domain of unknown function (DUF1899) Nup160 PF11715.8 OQR87535.1 - 0.052 12.2 0.8 6.2 5.3 0.1 2.9 3 1 0 3 3 3 0 Nucleoporin Nup120/160 Mg_trans_NIPA PF05653.14 OQR87537.1 - 3.1e-30 105.3 13.2 8.2e-17 61.3 3.9 2.1 2 0 0 2 2 2 2 Magnesium transporter NIPA EamA PF00892.20 OQR87537.1 - 0.00012 22.3 5.2 0.00012 22.3 5.2 4.0 3 2 1 4 4 4 1 EamA-like transporter family EmrE PF13536.6 OQR87537.1 - 0.045 13.3 11.4 1.6 8.3 10.6 2.7 1 1 0 1 1 1 0 Putative multidrug resistance efflux transporter UPF0060 PF02694.15 OQR87537.1 - 0.095 12.9 0.3 0.095 12.9 0.3 2.5 3 0 0 3 3 3 0 Uncharacterised BCR, YnfA/UPF0060 family PIRT PF15099.6 OQR87537.1 - 0.1 12.2 0.3 0.33 10.5 0.0 1.9 2 0 0 2 2 2 0 Phosphoinositide-interacting protein family Multi_Drug_Res PF00893.19 OQR87537.1 - 0.11 13.2 11.6 1.5 9.6 3.8 2.6 2 0 0 2 2 2 0 Small Multidrug Resistance protein TMEM234 PF10639.9 OQR87537.1 - 6 6.9 8.0 3 7.9 1.0 2.9 3 0 0 3 3 3 0 Putative transmembrane family 234 BT1 PF03092.16 OQR87554.1 - 0.0002 19.7 4.2 0.00056 18.3 2.1 2.2 2 1 0 2 2 2 1 BT1 family SUR7 PF06687.12 OQR87554.1 - 4.6 6.8 14.5 0.26 10.9 1.3 2.4 2 0 0 2 2 2 0 SUR7/PalI family DUF4231 PF14015.6 OQR87554.1 - 8 7.0 10.1 2.2 8.8 2.8 3.1 1 1 1 2 2 2 0 Protein of unknown function (DUF4231) MFS_1 PF07690.16 OQR87557.1 - 6e-46 157.0 61.8 1.4e-31 109.7 39.4 4.2 2 2 2 4 4 4 4 Major Facilitator Superfamily DUF5408 PF17402.2 OQR87557.1 - 0.38 10.7 3.5 18 5.3 0.4 2.8 2 0 0 2 2 2 0 Family of unknown function (DUF5408) Oxidored_FMN PF00724.20 OQR87631.1 - 1.1e-91 307.7 0.0 1.3e-91 307.5 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family PXT1 PF15214.6 OQR87632.1 - 0.023 15.1 0.4 0.057 13.8 0.1 1.8 2 0 0 2 2 2 0 Peroxisomal testis-specific protein 1 Pox_polyA_pol_N PF12630.7 OQR87633.1 - 0.024 15.0 0.3 0.025 14.9 0.3 1.2 1 0 0 1 1 1 0 Poxvirus poly(A) polymerase N-terminal domain DUF3021 PF11457.8 OQR87663.1 - 0.054 13.8 0.5 0.085 13.2 0.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3021) DUF4874 PF16173.5 OQR87663.1 - 0.12 12.0 0.0 0.19 11.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4874) Glyco_transf_28 PF03033.20 OQR87697.1 - 4.5e-12 46.2 0.0 6.5e-12 45.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain Colicin_Pyocin PF01320.18 OQR87697.1 - 0.069 13.3 0.0 0.13 12.4 0.0 1.4 1 0 0 1 1 1 0 Colicin immunity protein / pyocin immunity protein PTCB-BRCT PF12738.7 OQR87698.1 - 0.00058 19.8 0.0 0.14 12.1 0.0 3.1 3 0 0 3 3 3 2 twin BRCT domain TSLP PF15216.6 OQR87698.1 - 0.018 15.3 0.0 0.031 14.5 0.0 1.4 1 0 0 1 1 1 0 Thymic stromal lymphopoietin SK_channel PF03530.14 OQR87699.1 - 4.2e-13 49.3 1.7 1.1e-12 48.0 1.7 1.7 1 0 0 1 1 1 1 Calcium-activated SK potassium channel Ion_trans_2 PF07885.16 OQR87699.1 - 7.5e-13 48.3 11.8 3.9e-12 45.9 7.7 2.6 2 0 0 2 2 2 1 Ion channel Ion_trans PF00520.31 OQR87699.1 - 0.0031 16.8 17.4 0.067 12.4 17.5 2.5 1 1 0 1 1 1 1 Ion transport protein RTT107_BRCT_5 PF16770.5 OQR87700.1 - 0.00063 19.6 0.0 0.0066 16.3 0.0 2.1 2 0 0 2 2 2 1 Regulator of Ty1 transposition protein 107 BRCT domain BRCT PF00533.26 OQR87700.1 - 0.045 14.1 0.0 0.57 10.6 0.0 2.1 2 0 0 2 2 2 0 BRCA1 C Terminus (BRCT) domain MCM PF00493.23 OQR87701.1 - 1.5e-74 249.9 0.0 2.6e-74 249.1 0.0 1.4 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 OQR87701.1 - 6.5e-20 71.3 4.7 1.4e-19 70.2 4.5 1.7 2 0 0 2 2 2 1 MCM OB domain MCM_lid PF17855.1 OQR87701.1 - 8.2e-17 61.4 4.6 2.2e-16 60.1 4.3 1.9 2 0 0 2 2 2 1 MCM AAA-lid domain Mg_chelatase PF01078.21 OQR87701.1 - 7.3e-08 32.0 0.1 0.00045 19.7 0.0 2.8 1 1 1 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 OQR87701.1 - 4.7e-07 29.9 0.0 1e-06 28.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_30 PF13604.6 OQR87701.1 - 0.0023 17.7 0.1 0.023 14.4 0.1 2.3 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 OQR87701.1 - 0.031 14.7 0.1 0.21 11.9 0.1 2.3 2 1 0 2 2 2 0 AAA ATPase domain AAA PF00004.29 OQR87701.1 - 0.047 14.1 0.0 0.14 12.6 0.0 1.8 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_3 PF07726.11 OQR87701.1 - 0.05 13.5 0.0 0.16 11.8 0.0 1.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 OQR87701.1 - 0.068 12.9 0.0 4.8 6.9 0.0 2.5 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_22 PF13401.6 OQR87701.1 - 0.085 13.1 0.1 0.35 11.1 0.0 2.1 2 0 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.18 OQR87701.1 - 0.11 11.9 0.0 0.19 11.0 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_19 PF13245.6 OQR87701.1 - 0.12 12.7 0.3 1.5 9.2 0.0 2.6 2 1 1 3 3 3 0 AAA domain Ion_trans PF00520.31 OQR87702.1 - 7.3e-08 31.9 4.9 9.7e-08 31.5 4.9 1.1 1 0 0 1 1 1 1 Ion transport protein PKD_channel PF08016.12 OQR87702.1 - 7.2e-05 21.6 7.4 8.8e-05 21.4 7.4 1.1 1 0 0 1 1 1 1 Polycystin cation channel DivIC PF04977.15 OQR87702.1 - 0.0063 16.3 0.7 0.027 14.2 0.2 2.1 2 0 0 2 2 2 1 Septum formation initiator Pex24p PF06398.11 OQR87702.1 - 0.0087 15.1 0.1 0.013 14.5 0.1 1.2 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin Rab3-GTPase_cat PF13890.6 OQR87702.1 - 0.01 15.4 0.5 0.017 14.8 0.5 1.3 1 0 0 1 1 1 0 Rab3 GTPase-activating protein catalytic subunit DUF420 PF04238.12 OQR87702.1 - 0.25 11.6 2.8 0.37 11.1 2.7 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF420) Pkinase PF00069.25 OQR87718.1 - 2e-34 119.2 0.0 2.9e-34 118.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQR87718.1 - 9.6e-33 113.6 0.0 1.2e-32 113.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Ank_4 PF13637.6 OQR87718.1 - 7e-09 36.1 0.0 3.9e-07 30.5 0.0 3.2 2 1 1 3 3 3 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 OQR87718.1 - 1.2e-08 35.4 0.0 2.4e-08 34.4 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OQR87718.1 - 2.3e-07 30.5 0.1 0.01 16.3 0.0 4.1 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 OQR87718.1 - 7.2e-07 29.4 0.1 2.5e-06 27.6 0.1 2.0 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.30 OQR87718.1 - 0.00093 19.5 0.2 0.15 12.5 0.0 3.1 3 0 0 3 3 3 1 Ankyrin repeat Kinase-like PF14531.6 OQR87718.1 - 0.0018 17.7 0.0 0.0031 16.9 0.0 1.4 1 0 0 1 1 1 1 Kinase-like ABC_tran PF00005.27 OQR87721.1 - 8.5e-13 49.0 0.0 1.7e-12 48.0 0.0 1.5 1 0 0 1 1 1 1 ABC transporter LRR_9 PF14580.6 OQR87721.1 - 2.7e-12 46.6 0.2 2.6e-09 36.8 0.0 2.5 1 1 1 2 2 2 2 Leucine-rich repeat ABC_membrane PF00664.23 OQR87721.1 - 1.6e-10 41.1 10.9 1.5e-09 37.9 10.9 2.1 1 1 0 1 1 1 1 ABC transporter transmembrane region LRR_4 PF12799.7 OQR87721.1 - 1.4e-05 25.4 2.1 0.0081 16.6 0.1 3.9 1 1 2 4 4 4 1 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 OQR87721.1 - 0.03 14.1 3.5 0.21 11.4 0.1 2.8 2 0 0 2 2 2 0 Leucine rich repeat AAA_16 PF13191.6 OQR87721.1 - 0.051 13.9 0.0 0.14 12.6 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain Ank_2 PF12796.7 OQR87722.1 - 8.3e-36 122.4 0.7 1.1e-11 45.1 0.3 4.7 3 2 0 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OQR87722.1 - 2.2e-30 101.3 5.2 1.7e-05 24.8 0.0 7.9 8 1 0 8 8 8 6 Ankyrin repeat Ank PF00023.30 OQR87722.1 - 1.6e-28 97.9 10.8 9.3e-07 29.0 0.0 7.9 8 0 0 8 8 8 5 Ankyrin repeat Ank_4 PF13637.6 OQR87722.1 - 3.8e-28 97.5 4.8 2.6e-10 40.6 0.1 6.8 5 1 1 6 6 6 6 Ankyrin repeats (many copies) Ank_5 PF13857.6 OQR87722.1 - 8.4e-21 73.8 10.6 5.2e-05 23.4 0.1 7.3 5 1 2 7 7 7 6 Ankyrin repeats (many copies) TIR_2 PF13676.6 OQR87722.1 - 1.5e-13 51.4 0.0 6.4e-07 30.0 0.0 2.9 2 0 0 2 2 2 2 TIR domain Chromate_transp PF02417.15 OQR87723.1 - 0.81 9.8 9.6 1.8 8.7 0.0 3.1 3 0 0 3 3 3 0 Chromate transporter Retrotrans_gag PF03732.17 OQR87777.1 - 0.00076 19.7 0.0 0.0011 19.2 0.0 1.3 1 0 0 1 1 1 1 Retrotransposon gag protein Asp_protease_2 PF13650.6 OQR87778.1 - 0.0091 16.6 0.0 0.019 15.6 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 OQR87778.1 - 0.013 16.1 0.0 0.024 15.2 0.0 1.5 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 OQR87778.1 - 0.06 13.1 0.0 8.1 6.2 0.0 2.3 1 1 1 2 2 2 0 Retroviral aspartyl protease RVP PF00077.20 OQR87778.1 - 0.076 13.3 0.0 0.17 12.2 0.0 1.5 1 0 0 1 1 1 0 Retroviral aspartyl protease ARL2_Bind_BART PF11527.8 OQR87810.1 - 1.2e-19 70.6 2.4 1.3e-19 70.4 2.4 1.0 1 0 0 1 1 1 1 The ARF-like 2 binding protein BART FadR_C PF07840.12 OQR87810.1 - 0.0028 17.6 0.1 0.0037 17.2 0.1 1.3 1 1 0 1 1 1 1 FadR C-terminal domain Ax_dynein_light PF10211.9 OQR87860.1 - 7.9e-73 244.4 3.0 1e-72 244.0 3.0 1.1 1 0 0 1 1 1 1 Axonemal dynein light chain DUF572 PF04502.13 OQR87860.1 - 0.022 14.4 3.3 0.034 13.8 3.3 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) GrpE PF01025.19 OQR87860.1 - 0.078 12.6 4.1 0.17 11.5 4.1 1.5 1 0 0 1 1 1 0 GrpE DivIC PF04977.15 OQR87860.1 - 2.3 8.1 7.1 0.51 10.1 2.8 2.1 2 1 1 3 3 3 0 Septum formation initiator TTC5_OB PF16669.5 OQR87861.1 - 2.9e-19 68.9 0.1 4.1e-19 68.4 0.1 1.2 1 0 0 1 1 1 1 Tetratricopeptide repeat protein 5 OB fold domain TPR_1 PF00515.28 OQR87861.1 - 2.9e-08 33.2 3.5 1e-07 31.4 0.1 3.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.17 OQR87861.1 - 7.5e-08 31.9 4.3 1.2e-07 31.3 0.2 2.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.6 OQR87861.1 - 1.1e-06 28.2 7.6 0.0007 19.2 0.2 3.7 3 1 1 4 4 4 2 TPR repeat TPR_16 PF13432.6 OQR87861.1 - 2e-05 25.2 1.2 3.7e-05 24.3 1.2 1.4 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_8 PF13181.6 OQR87861.1 - 7.7e-05 22.6 0.1 0.00093 19.2 0.0 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 OQR87861.1 - 0.005 17.1 1.7 0.016 15.4 1.7 1.9 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_7 PF13176.6 OQR87861.1 - 0.011 15.7 0.6 0.064 13.3 0.2 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_17 PF13431.6 OQR87861.1 - 0.066 13.6 0.2 0.4 11.2 0.1 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 OQR87861.1 - 0.45 11.5 5.7 0.61 11.1 0.1 3.0 3 1 1 4 4 4 0 Tetratricopeptide repeat EamA PF00892.20 OQR87862.1 - 7.3e-13 48.9 38.0 1.2e-06 28.8 14.9 2.3 2 0 0 2 2 2 2 EamA-like transporter family DUF1186 PF06685.11 OQR87863.1 - 0.092 12.1 0.1 0.23 10.8 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1186) Coilin_N PF15862.5 OQR87863.1 - 2 8.2 9.0 0.82 9.5 0.6 2.4 2 0 0 2 2 2 0 Coilin N-terminus NAD_binding_1 PF00175.21 OQR87865.1 - 1.4e-12 48.2 0.0 3.7e-12 46.9 0.0 1.8 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 OQR87865.1 - 3.2e-11 43.5 0.0 5.5e-11 42.7 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain Globin PF00042.22 OQR87865.1 - 5.5e-09 36.6 0.0 1e-08 35.7 0.0 1.5 1 0 0 1 1 1 1 Globin NAD_binding_6 PF08030.12 OQR87865.1 - 6.2e-07 29.7 0.0 5.4e-05 23.4 0.0 2.3 1 1 1 2 2 2 2 Ferric reductase NAD binding domain HTH_33 PF13592.6 OQR87866.1 - 0.006 16.2 0.0 0.0086 15.7 0.0 1.3 1 0 0 1 1 1 1 Winged helix-turn helix Thioredoxin_8 PF13905.6 OQR87926.1 - 8.9e-58 192.6 0.0 2.2e-29 101.6 0.0 2.5 2 0 0 2 2 2 2 Thioredoxin-like Thioredoxin PF00085.20 OQR87926.1 - 6.9e-18 64.5 0.1 5.2e-06 26.4 0.0 4.3 3 1 1 4 4 4 3 Thioredoxin Redoxin PF08534.10 OQR87926.1 - 9.3e-18 64.3 0.0 7.7e-11 41.9 0.0 2.3 2 0 0 2 2 2 2 Redoxin AhpC-TSA PF00578.21 OQR87926.1 - 4.7e-16 58.8 0.0 2.5e-08 33.9 0.0 2.6 2 0 0 2 2 2 2 AhpC/TSA family Thioredoxin_2 PF13098.6 OQR87926.1 - 1.1e-15 58.0 0.0 1.1e-07 32.2 0.0 2.5 2 0 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_7 PF13899.6 OQR87926.1 - 5.5e-11 42.5 0.0 0.00023 21.3 0.0 3.1 2 1 0 2 2 2 2 Thioredoxin-like SCO1-SenC PF02630.14 OQR87926.1 - 7.3e-07 29.2 0.1 0.011 15.7 0.0 2.5 2 0 0 2 2 2 2 SCO1/SenC Thioredoxin_9 PF14595.6 OQR87926.1 - 2.1e-05 24.3 0.0 0.14 11.9 0.0 3.2 2 1 0 2 2 2 2 Thioredoxin ZZ PF00569.17 OQR87926.1 - 4.4e-05 23.2 7.9 9.5e-05 22.1 7.9 1.5 1 0 0 1 1 1 1 Zinc finger, ZZ type Glutaredoxin PF00462.24 OQR87926.1 - 0.004 17.4 0.0 8.5 6.7 0.0 3.9 2 2 0 2 2 2 2 Glutaredoxin TraF PF13728.6 OQR87926.1 - 0.068 13.0 0.0 3.2 7.5 0.0 2.6 2 1 0 2 2 2 0 F plasmid transfer operon protein C1_2 PF03107.16 OQR87926.1 - 0.67 10.3 7.9 2.2 8.6 7.9 1.9 1 0 0 1 1 1 0 C1 domain EF-hand_7 PF13499.6 OQR87929.1 - 1.6e-17 63.7 4.7 1.8e-06 28.3 0.0 4.5 3 1 0 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.6 OQR87929.1 - 2.6e-08 33.1 16.4 0.026 14.4 0.1 7.5 8 0 0 8 8 8 2 EF-hand domain EF-hand_1 PF00036.32 OQR87929.1 - 6.8e-08 31.5 14.9 4.6e-05 22.7 0.3 5.9 7 1 1 8 8 8 3 EF hand EF-hand_8 PF13833.6 OQR87929.1 - 1e-07 31.7 3.0 0.0013 18.6 0.1 3.6 4 0 0 4 4 4 2 EF-hand domain pair EF-hand_4 PF12763.7 OQR87929.1 - 0.00019 21.3 6.1 0.059 13.3 0.1 3.9 2 2 2 4 4 4 2 Cytoskeletal-regulatory complex EF hand EF-hand_5 PF13202.6 OQR87929.1 - 0.00053 19.4 10.3 0.012 15.1 0.2 4.7 5 0 0 5 5 5 2 EF hand Dockerin_1 PF00404.18 OQR87929.1 - 0.016 15.4 0.4 0.22 11.7 0.2 2.8 2 1 0 2 2 2 0 Dockerin type I domain EF-hand_11 PF08976.11 OQR87929.1 - 0.018 15.9 0.1 0.098 13.5 0.1 2.3 2 0 0 2 2 2 0 EF-hand domain DUF1380 PF07128.12 OQR87929.1 - 0.051 13.8 0.0 0.28 11.3 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1380) 3HCDH_N PF02737.18 OQR87930.1 - 2.5e-55 187.1 0.4 2.5e-55 187.1 0.4 1.9 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.22 OQR87930.1 - 2.5e-35 120.9 0.2 2.8e-25 88.7 0.0 3.7 4 0 0 4 4 4 2 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain ECH_1 PF00378.20 OQR87930.1 - 6.4e-11 42.0 0.2 1.4e-10 40.9 0.2 1.6 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase NAD_binding_2 PF03446.15 OQR87930.1 - 0.0053 16.9 0.3 0.014 15.6 0.1 1.9 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase PGP_phosphatase PF09419.10 OQR87930.1 - 0.017 14.8 0.1 0.033 13.8 0.1 1.4 1 0 0 1 1 1 0 Mitochondrial PGP phosphatase Pyr_redox PF00070.27 OQR87930.1 - 0.057 14.0 0.1 0.19 12.3 0.1 1.9 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OQR87930.1 - 0.13 12.6 0.1 0.41 10.9 0.1 1.9 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain RAB3GAP2_C PF14656.6 OQR87941.1 - 8.6e-13 47.4 1.0 4.6e-09 35.1 0.0 2.8 2 2 0 2 2 2 2 Rab3 GTPase-activating protein regulatory subunit C-terminus RRM_1 PF00076.22 OQR87942.1 - 0.00015 21.5 0.0 0.0004 20.2 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4286 PF14114.6 OQR87942.1 - 0.026 15.0 0.3 0.026 15.0 0.3 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4286) GAGA_bind PF06217.12 OQR87942.1 - 1.5 9.1 10.5 1.8 8.8 10.5 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family AAA_11 PF13086.6 OQR87942.1 - 3 7.5 11.4 3.9 7.2 11.4 1.1 1 0 0 1 1 1 0 AAA domain PGC7_Stella PF15549.6 OQR87942.1 - 4.4 7.3 10.8 5.9 6.9 6.2 2.1 1 1 0 2 2 2 0 PGC7/Stella/Dppa3 domain DUF4478 PF14793.6 OQR87987.1 - 0.17 11.8 0.1 0.42 10.5 0.0 1.6 2 0 0 2 2 2 0 Pyrimidine/purine nucleotide 5'-monophosphate nucleosidases LRR_8 PF13855.6 OQR87988.1 - 7.3e-22 76.9 56.4 9.3e-06 25.3 2.9 8.8 4 3 4 9 9 9 8 Leucine rich repeat LRR_4 PF12799.7 OQR87988.1 - 2.2e-19 69.2 66.5 8.4e-05 22.9 0.2 9.8 7 3 6 13 13 13 10 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 OQR87988.1 - 2.6e-15 55.1 34.2 0.054 13.6 0.5 13.2 14 0 0 14 14 14 5 Leucine Rich repeat FNIP PF05725.12 OQR87988.1 - 1.8e-05 24.8 27.9 0.31 11.2 5.5 6.4 5 1 0 5 5 5 3 FNIP Repeat LRR_1 PF00560.33 OQR87988.1 - 0.0008 19.6 51.7 1.3 9.8 0.0 13.1 11 3 2 13 13 13 1 Leucine Rich Repeat LRR_9 PF14580.6 OQR87988.1 - 0.0013 18.3 18.1 0.37 10.3 0.5 4.9 3 3 2 5 5 5 3 Leucine-rich repeat Pentapeptide_4 PF13599.6 OQR87988.1 - 0.034 14.3 0.3 0.36 11.0 0.2 2.8 2 0 0 2 2 2 0 Pentapeptide repeats (9 copies) PMP1_2 PF08114.11 OQR87988.1 - 0.041 13.6 0.5 0.15 11.8 0.2 2.1 2 0 0 2 2 2 0 ATPase proteolipid family DUF4199 PF13858.6 OQR87988.1 - 0.061 13.7 3.0 1.6 9.1 0.0 3.4 4 0 0 4 4 4 0 Protein of unknown function (DUF4199) YrhC PF14143.6 OQR87988.1 - 0.35 11.0 1.2 3.9 7.6 0.0 2.8 3 0 0 3 3 3 0 YrhC-like protein Pkinase_Tyr PF07714.17 OQR87989.1 - 9.2e-23 80.8 0.0 5.8e-19 68.4 0.0 2.2 1 1 1 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 OQR87989.1 - 1.3e-15 57.5 0.0 7.5e-14 51.7 0.0 2.1 1 1 1 2 2 2 2 Protein kinase domain DSPn PF14671.6 OQR88024.1 - 2.4e-08 34.5 0.1 3.2e-07 30.9 0.1 2.2 2 0 0 2 2 2 1 Dual specificity protein phosphatase, N-terminal half Sugar_tr PF00083.24 OQR88025.1 - 2e-31 109.4 39.0 1.1e-30 106.9 34.7 2.5 2 1 0 2 2 2 1 Sugar (and other) transporter MFS_1 PF07690.16 OQR88025.1 - 6.6e-22 77.9 42.5 4.5e-16 58.7 16.4 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily Radical_SAM PF04055.21 OQR88025.1 - 1.6e-12 48.1 0.0 3.4e-12 47.1 0.0 1.6 1 0 0 1 1 1 1 Radical SAM superfamily TRI12 PF06609.13 OQR88025.1 - 1.4e-06 27.1 2.4 2.9e-06 26.0 2.4 1.5 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Fer4_14 PF13394.6 OQR88025.1 - 0.011 15.8 0.0 0.038 14.1 0.0 1.9 1 0 0 1 1 1 0 4Fe-4S single cluster domain Ank_2 PF12796.7 OQR88076.1 - 7.6e-82 270.0 17.1 1.8e-15 57.3 0.4 6.7 1 1 5 7 7 7 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQR88076.1 - 2.7e-68 225.5 16.5 2.8e-09 37.3 0.1 10.9 3 3 8 12 12 12 11 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQR88076.1 - 6.7e-60 192.0 14.1 0.00081 19.7 0.0 14.4 15 0 0 15 15 15 13 Ankyrin repeat Ank PF00023.30 OQR88076.1 - 2.4e-55 182.7 36.0 0.00012 22.3 0.2 14.4 14 1 1 15 15 15 14 Ankyrin repeat Ank_5 PF13857.6 OQR88076.1 - 2.1e-42 142.6 22.7 7.6e-07 29.3 0.2 10.4 2 2 7 11 11 11 11 Ankyrin repeats (many copies) Imm_superinfect PF14373.6 OQR88076.1 - 0.0066 16.3 2.8 10 6.1 0.0 5.6 6 0 0 6 6 6 1 Superinfection immunity protein GATase_7 PF13537.6 OQR88076.1 - 0.015 15.2 0.0 20 5.1 0.0 4.9 4 1 0 5 5 5 0 Glutamine amidotransferase domain Nitro_FeMo-Co PF02579.17 OQR88076.1 - 0.052 13.9 0.6 56 4.2 0.2 3.9 3 1 1 4 4 4 0 Dinitrogenase iron-molybdenum cofactor VWA_3_C PF18571.1 OQR88076.1 - 1.4 8.8 3.8 25 4.8 0.1 4.3 5 0 0 5 5 5 0 von Willebrand factor type A C-terminal domain Pkinase PF00069.25 OQR88077.1 - 1.3e-39 136.2 0.0 1.7e-39 135.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQR88077.1 - 3.5e-33 115.0 0.0 4.3e-33 114.7 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OQR88077.1 - 5.4e-06 25.4 0.1 1.1e-05 24.5 0.0 1.5 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 OQR88077.1 - 0.00095 18.6 0.0 0.0015 17.9 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 OQR88077.1 - 0.0076 15.6 0.0 0.012 15.0 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Yuri_gagarin PF15934.5 OQR88128.1 - 0.015 15.2 0.0 0.032 14.1 0.0 1.5 1 0 0 1 1 1 0 Yuri gagarin C_Hendra PF16821.5 OQR88128.1 - 0.39 10.6 8.8 1.1 9.2 8.8 1.7 1 0 0 1 1 1 0 C protein from hendra and measles viruses Condensation PF00668.20 OQR88129.1 - 0.015 14.0 0.4 0.079 11.6 0.0 1.9 2 0 0 2 2 2 0 Condensation domain Cation_ATPase_N PF00690.26 OQR88130.1 - 1.7e-12 46.9 0.0 2e-12 46.6 0.0 1.1 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Baculo_E66 PF04850.12 OQR88143.1 - 0.0051 15.7 0.4 0.0052 15.6 0.4 1.1 1 0 0 1 1 1 1 Baculovirus E66 occlusion-derived virus envelope protein BCHF PF07284.11 OQR88143.1 - 0.07 13.1 0.6 0.084 12.9 0.6 1.1 1 0 0 1 1 1 0 2-vinyl bacteriochlorophyllide hydratase (BCHF) DDE_Tnp_1_7 PF13843.6 OQR88144.1 - 1.2e-13 51.1 0.0 1.5e-13 50.8 0.0 1.0 1 0 0 1 1 1 1 Transposase IS4 DDE_Tnp_1 PF01609.21 OQR88144.1 - 0.087 12.5 0.0 0.093 12.4 0.0 1.4 1 1 0 1 1 1 0 Transposase DDE domain Pre-PUA PF17832.1 OQR88146.1 - 3.6e-05 24.4 0.0 0.00027 21.5 0.0 2.4 2 0 0 2 2 2 1 Pre-PUA-like domain SWIB PF02201.18 OQR88146.1 - 0.025 14.5 0.0 0.06 13.2 0.0 1.6 1 0 0 1 1 1 0 SWIB/MDM2 domain Kin17_mid PF10357.9 OQR88146.1 - 0.048 13.6 0.0 0.1 12.5 0.0 1.5 1 0 0 1 1 1 0 Domain of Kin17 curved DNA-binding protein Ephrin_lbd PF01404.19 OQR88146.1 - 0.17 12.0 0.0 0.31 11.1 0.0 1.4 1 0 0 1 1 1 0 Ephrin receptor ligand binding domain DDE_1 PF03184.19 OQR88199.1 - 1.4e-21 76.9 0.3 7.7e-11 41.9 0.1 2.1 1 1 1 2 2 2 2 DDE superfamily endonuclease DEC-1_N PF04625.13 OQR88200.1 - 0.45 9.5 1.8 0.45 9.5 1.8 1.1 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region COesterase PF00135.28 OQR88204.1 - 9.4e-17 61.0 1.1 2.2e-16 59.8 1.1 1.5 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 OQR88204.1 - 7.6e-16 58.6 0.0 1.5e-15 57.6 0.0 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 OQR88204.1 - 7.8e-07 29.9 0.3 1.2e-06 29.3 0.3 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 OQR88204.1 - 2.6e-05 23.8 0.2 0.0009 18.8 0.1 2.3 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 OQR88204.1 - 0.00075 19.2 0.8 0.0018 18.0 0.8 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 OQR88204.1 - 0.0032 16.8 0.2 0.25 10.6 0.1 2.6 3 0 0 3 3 3 1 Serine aminopeptidase, S33 Chlorophyllase2 PF12740.7 OQR88204.1 - 0.013 14.4 0.0 0.021 13.8 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase enzyme Chlorophyllase PF07224.11 OQR88204.1 - 0.031 13.3 0.0 0.048 12.7 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase DLH PF01738.18 OQR88204.1 - 0.1 12.2 0.6 0.26 10.8 0.1 1.8 2 0 0 2 2 2 0 Dienelactone hydrolase family Abhydrolase_2 PF02230.16 OQR88204.1 - 0.11 12.3 0.1 0.29 10.9 0.0 1.6 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Pkinase PF00069.25 OQR88205.1 - 2.7e-51 174.4 0.0 4.6e-51 173.7 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain RyR PF02026.16 OQR88205.1 - 3.6e-43 145.7 0.1 7.4e-21 74.2 0.0 2.5 2 0 0 2 2 2 2 RyR domain Pkinase_Tyr PF07714.17 OQR88205.1 - 1e-25 90.5 0.0 2.1e-17 63.3 0.1 2.8 2 1 0 2 2 2 2 Protein tyrosine kinase APH PF01636.23 OQR88205.1 - 1.3e-05 25.3 0.0 0.2 11.5 0.5 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kinase-like PF14531.6 OQR88205.1 - 2.4e-05 23.8 0.0 0.0061 15.9 0.0 2.3 2 0 0 2 2 2 2 Kinase-like Pkinase_fungal PF17667.1 OQR88205.1 - 0.0003 19.7 0.0 0.00055 18.8 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase PH PF00169.29 OQR88205.1 - 0.011 16.2 0.0 0.027 15.0 0.0 1.6 1 0 0 1 1 1 0 PH domain PH_8 PF15409.6 OQR88205.1 - 0.047 14.0 0.0 0.11 12.8 0.0 1.6 1 0 0 1 1 1 0 Pleckstrin homology domain IQ_SEC7_PH PF16453.5 OQR88205.1 - 0.058 13.4 0.0 0.15 12.0 0.0 1.6 1 0 0 1 1 1 0 PH domain Ion_trans PF00520.31 OQR88208.1 - 3.2e-57 193.6 36.5 8.5e-35 120.1 13.8 2.1 2 0 0 2 2 2 2 Ion transport protein DEP PF00610.21 OQR88208.1 - 3.6e-07 30.2 0.0 6.7e-07 29.3 0.0 1.5 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) PKD_channel PF08016.12 OQR88208.1 - 0.0042 15.8 25.5 0.055 12.1 1.4 4.3 2 2 2 4 4 4 3 Polycystin cation channel Ion_trans PF00520.31 OQR88209.1 - 0.0033 16.7 0.4 0.0036 16.6 0.4 1.0 1 0 0 1 1 1 1 Ion transport protein Ion_trans PF00520.31 OQR88210.1 - 2.6e-22 79.3 2.0 3.6e-22 78.8 2.0 1.2 1 0 0 1 1 1 1 Ion transport protein EF-hand_1 PF00036.32 OQR88210.1 - 8.6e-13 46.8 3.7 0.00041 19.7 0.2 4.6 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.6 OQR88210.1 - 2.5e-11 42.5 2.4 0.0043 16.9 0.1 4.7 4 0 0 4 4 4 3 EF-hand domain EF-hand_7 PF13499.6 OQR88210.1 - 1.1e-10 41.8 2.0 1.7e-07 31.6 0.8 3.3 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_5 PF13202.6 OQR88210.1 - 7.1e-07 28.4 4.9 0.024 14.1 0.2 3.9 4 0 0 4 4 4 2 EF hand EF-hand_8 PF13833.6 OQR88210.1 - 4.2e-06 26.5 1.7 0.31 10.9 0.1 4.0 3 1 1 4 4 4 2 EF-hand domain pair SieB PF14163.6 OQR88210.1 - 0.74 9.3 8.6 0.014 14.9 1.8 1.6 2 0 0 2 2 2 0 Super-infection exclusion protein B DUF2534 PF10749.9 OQR88210.1 - 1.8 8.8 8.8 1.3 9.2 3.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2534) ABC_membrane PF00664.23 OQR88211.1 - 9.3e-25 87.8 12.8 1.4e-24 87.2 12.8 1.3 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 OQR88211.1 - 0.01 16.3 0.0 0.026 15.0 0.0 1.7 1 0 0 1 1 1 0 ABC transporter UPF0029 PF01205.19 OQR88232.1 - 3.6e-11 43.3 0.0 7.2e-11 42.4 0.0 1.6 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 MT PF12777.7 OQR88232.1 - 1.9e-05 23.9 0.0 2.8e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor EF-hand_7 PF13499.6 OQR88233.1 - 1.5e-20 73.4 1.0 7.2e-13 48.8 0.3 2.3 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 OQR88233.1 - 3.5e-19 68.4 5.3 9.5e-12 44.6 0.5 3.2 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_1 PF00036.32 OQR88233.1 - 6.7e-19 66.0 6.1 2.6e-07 29.7 1.5 3.5 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.6 OQR88233.1 - 4.1e-13 48.1 1.3 0.00015 21.4 0.1 4.3 4 1 0 4 4 4 2 EF-hand domain EF-hand_9 PF14658.6 OQR88233.1 - 9.2e-10 38.7 0.0 0.00028 21.2 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 OQR88233.1 - 1.6e-05 24.2 5.6 0.031 13.8 1.2 3.4 3 0 0 3 3 3 2 EF hand EF-hand_4 PF12763.7 OQR88233.1 - 0.00016 21.6 0.1 0.015 15.2 0.1 2.2 2 0 0 2 2 2 1 Cytoskeletal-regulatory complex EF hand SurA_N_3 PF13624.6 OQR88233.1 - 0.093 12.5 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 SurA N-terminal domain p25-alpha PF05517.12 OQR88233.1 - 0.095 12.9 0.0 4.7 7.4 0.0 2.0 1 1 1 2 2 2 0 p25-alpha F-box PF00646.33 OQR88234.1 - 0.016 15.1 0.6 0.096 12.6 0.1 2.4 2 0 0 2 2 2 0 F-box domain LRR_1 PF00560.33 OQR88234.1 - 0.21 12.3 3.1 84 4.3 0.0 3.9 4 0 0 4 4 4 0 Leucine Rich Repeat adh_short PF00106.25 OQR88247.1 - 1.2e-28 99.9 0.1 6.4e-22 78.0 0.1 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 OQR88247.1 - 2.2e-20 73.2 0.0 8.9e-15 54.9 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OQR88247.1 - 3.2e-07 30.4 0.0 5.5e-07 29.7 0.0 1.5 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 OQR88247.1 - 1.8e-05 24.0 0.1 3.1e-05 23.3 0.1 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.21 OQR88247.1 - 0.0019 17.7 0.1 0.021 14.3 0.1 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF3228 PF11539.8 OQR88253.1 - 5.9e-86 287.0 0.0 6.6e-86 286.8 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3228) EF-hand_5 PF13202.6 OQR88254.1 - 0.00092 18.6 0.2 0.0028 17.1 0.1 1.9 2 0 0 2 2 2 1 EF hand EF-hand_1 PF00036.32 OQR88254.1 - 0.0012 18.3 2.0 0.0033 16.8 0.6 2.4 2 0 0 2 2 2 1 EF hand WD40 PF00400.32 OQR88254.1 - 0.0013 19.5 5.6 17 6.5 0.0 6.6 7 0 0 7 7 7 1 WD domain, G-beta repeat EF-hand_6 PF13405.6 OQR88254.1 - 0.0024 17.7 0.4 0.017 15.0 0.1 2.5 2 0 0 2 2 2 1 EF-hand domain EF-hand_7 PF13499.6 OQR88254.1 - 0.005 17.3 0.2 0.014 15.8 0.2 1.8 1 0 0 1 1 1 1 EF-hand domain pair SIP1 PF04938.12 OQR88254.1 - 0.047 13.4 1.5 0.081 12.6 1.5 1.4 1 0 0 1 1 1 0 Survival motor neuron (SMN) interacting protein 1 (SIP1) EF-hand_8 PF13833.6 OQR88254.1 - 0.1 12.4 0.2 0.39 10.6 0.2 1.9 1 0 0 1 1 1 0 EF-hand domain pair PAS PF00989.25 OQR88266.1 - 0.21 11.6 0.2 0.21 11.6 0.2 1.7 2 0 0 2 2 2 0 PAS fold DUF3586 PF12131.8 OQR88266.1 - 5 7.4 13.9 4.5 7.6 2.6 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3586) CRAL_TRIO PF00650.20 OQR88269.1 - 1.9e-20 73.2 0.1 3.7e-20 72.2 0.1 1.5 1 0 0 1 1 1 1 CRAL/TRIO domain GOLD_2 PF13897.6 OQR88269.1 - 0.00019 22.0 10.9 0.0044 17.5 0.0 3.7 2 2 2 4 4 4 2 Golgi-dynamics membrane-trafficking ACBP PF00887.19 OQR88270.1 - 4.3e-13 49.3 0.0 1e-12 48.1 0.0 1.7 1 0 0 1 1 1 1 Acyl CoA binding protein CBM_1 PF00734.18 OQR88310.1 - 5.6e-13 48.6 5.5 5.6e-13 48.6 5.5 2.1 3 0 0 3 3 3 1 Fungal cellulose binding domain cNMP_binding PF00027.29 OQR88322.1 - 3.3e-16 59.1 0.0 6.1e-16 58.3 0.0 1.4 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Ion_trans PF00520.31 OQR88322.1 - 6.7e-06 25.5 13.3 1.4e-05 24.4 13.3 1.5 1 1 0 1 1 1 1 Ion transport protein AhpC-TSA PF00578.21 OQR88328.1 - 2e-32 111.7 0.0 2.8e-32 111.2 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 OQR88328.1 - 6.7e-14 51.8 0.0 8.9e-14 51.4 0.0 1.1 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.9 OQR88328.1 - 1.3e-11 44.1 0.0 2.2e-11 43.4 0.0 1.4 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin LRR_6 PF13516.6 OQR88329.1 - 1.9e-18 64.9 8.1 0.0011 18.9 0.1 7.7 7 0 0 7 7 7 4 Leucine Rich repeat LRR_4 PF12799.7 OQR88329.1 - 0.0038 17.6 20.7 0.89 10.1 0.2 6.2 3 1 4 7 7 7 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 OQR88329.1 - 0.2 12.3 10.7 59 4.8 0.0 6.2 6 1 0 6 6 6 0 Leucine Rich Repeat EF-hand_1 PF00036.32 OQR88330.1 - 0.00016 21.0 0.1 0.00042 19.6 0.1 1.8 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 OQR88330.1 - 0.0015 18.3 0.0 0.0068 16.3 0.0 2.2 2 0 0 2 2 2 1 EF-hand domain EF-hand_7 PF13499.6 OQR88330.1 - 0.0043 17.5 0.1 0.015 15.7 0.1 1.9 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.6 OQR88330.1 - 0.0059 16.1 0.0 0.015 14.8 0.0 1.7 1 0 0 1 1 1 1 EF hand IQ PF00612.27 OQR88330.1 - 0.019 14.7 0.2 0.049 13.4 0.2 1.8 1 0 0 1 1 1 0 IQ calmodulin-binding motif Voldacs PF03517.13 OQR88330.1 - 0.046 13.8 0.7 0.58 10.3 0.1 2.2 2 0 0 2 2 2 0 Regulator of volume decrease after cellular swelling EF-hand_4 PF12763.7 OQR88330.1 - 0.26 11.3 1.6 0.48 10.4 0.1 2.3 3 0 0 3 3 3 0 Cytoskeletal-regulatory complex EF hand GRDP-like PF07173.12 OQR88331.1 - 8.7e-14 52.4 0.3 2.6e-13 50.9 0.3 1.8 1 0 0 1 1 1 1 Glycine-rich domain-containing protein-like TerY_C PF15616.6 OQR88331.1 - 0.21 11.7 1.6 0.76 9.9 1.6 2.0 1 0 0 1 1 1 0 TerY-C metal binding domain zf-ribbon_3 PF13248.6 OQR88331.1 - 1 8.9 5.0 11 5.6 0.1 3.4 3 0 0 3 3 3 0 zinc-ribbon domain HypA PF01155.19 OQR88331.1 - 1.2 9.2 4.4 6.4 6.8 0.9 2.5 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DZR PF12773.7 OQR88331.1 - 1.8 8.6 5.9 2.9 8.0 0.9 2.7 1 1 1 2 2 2 0 Double zinc ribbon Pkinase PF00069.25 OQR88357.1 - 8.6e-19 67.9 0.6 1.1e-08 34.7 0.1 2.7 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OQR88357.1 - 8.6e-11 41.6 0.3 1.3e-05 24.6 0.1 2.1 1 1 1 2 2 2 2 Protein tyrosine kinase Mpv17_PMP22 PF04117.12 OQR88358.1 - 1.5e-20 73.1 3.5 3e-20 72.2 3.5 1.4 1 0 0 1 1 1 1 Mpv17 / PMP22 family HSP70 PF00012.20 OQR88359.1 - 1.2e-260 865.9 5.9 1.4e-260 865.6 5.9 1.1 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 OQR88359.1 - 9.6e-18 64.1 0.1 1.3e-16 60.4 0.0 2.2 2 0 0 2 2 2 1 MreB/Mbl protein M20_dimer PF07687.14 OQR88359.1 - 6.5e-09 35.7 0.4 1.9e-08 34.2 0.4 1.7 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M20 PF01546.28 OQR88359.1 - 9.9e-06 25.4 0.1 2.5e-05 24.1 0.1 1.8 2 0 0 2 2 2 1 Peptidase family M20/M25/M40 FGGY_C PF02782.16 OQR88359.1 - 0.013 15.2 0.0 0.031 14.0 0.0 1.6 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain MutS_III PF05192.18 OQR88359.1 - 0.085 13.1 0.4 4.8 7.3 0.1 2.3 2 0 0 2 2 2 0 MutS domain III TRAF_BIRC3_bd PF16673.5 OQR88359.1 - 0.085 12.7 0.2 0.25 11.1 0.2 1.8 1 0 0 1 1 1 0 TNF receptor-associated factor BIRC3 binding domain DDE_Tnp_4 PF13359.6 OQR88360.1 - 9.6e-18 64.3 0.0 1.3e-17 64.0 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_1 PF01609.21 OQR88360.1 - 4.2e-06 26.6 0.1 6.4e-05 22.7 0.0 2.1 1 1 1 2 2 2 1 Transposase DDE domain RRM_1 PF00076.22 OQR88362.1 - 0.00043 20.1 0.0 0.0012 18.6 0.0 1.9 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ubiquitin_4 PF18036.1 OQR88362.1 - 0.0052 16.8 3.5 0.94 9.6 0.2 3.7 4 0 0 4 4 4 1 Ubiquitin-like domain T3SSipB PF16535.5 OQR88362.1 - 0.37 11.3 10.3 0.9 10.0 10.3 1.7 1 0 0 1 1 1 0 Type III cell invasion protein SipB Histone PF00125.24 OQR88364.1 - 3.8e-49 166.4 3.5 4.2e-49 166.2 3.5 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 OQR88364.1 - 0.0002 21.7 0.0 0.00041 20.7 0.0 1.5 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 OQR88364.1 - 0.00061 19.9 0.2 0.0013 18.8 0.0 1.7 1 1 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CBFD_NFYB_HMF PF00808.23 OQR88364.1 - 0.0014 18.8 0.2 0.011 15.9 0.0 2.0 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone PAF PF15715.5 OQR88364.1 - 0.016 15.8 0.8 0.019 15.5 0.8 1.1 1 0 0 1 1 1 0 PCNA-associated factor histone like domain p450 PF00067.22 OQR88365.1 - 9.7e-63 212.5 0.0 1.6e-62 211.8 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Rop PF01815.16 OQR88366.1 - 0.052 13.4 0.3 0.052 13.4 0.3 1.9 2 0 0 2 2 2 0 Rop protein FAM178 PF14816.6 OQR88366.1 - 0.6 9.0 5.6 5.3 5.9 5.2 2.5 2 1 0 2 2 2 0 Family of unknown function, FAM178 Importin_rep_4 PF18808.1 OQR88368.1 - 3.8e-10 39.9 0.1 3.8e-10 39.9 0.1 4.3 3 2 2 5 5 5 1 Importin repeat HEAT_2 PF13646.6 OQR88368.1 - 8.9e-10 38.8 1.6 0.35 11.3 0.0 7.6 6 1 2 8 8 8 2 HEAT repeats HEAT PF02985.22 OQR88368.1 - 9.5e-09 34.8 5.5 4.6 7.8 0.0 9.6 10 0 0 10 10 10 2 HEAT repeat HEAT_EZ PF13513.6 OQR88368.1 - 0.0054 17.2 14.0 1.4 9.5 0.0 8.7 11 2 0 11 11 11 1 HEAT-like repeat UME PF08064.13 OQR88368.1 - 0.02 14.8 12.3 5.8 6.9 0.2 6.0 3 2 2 5 5 5 0 UME (NUC010) domain MtrH PF02007.18 OQR88368.1 - 0.025 13.7 0.1 0.044 12.9 0.1 1.3 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase MtrH subunit CLASP_N PF12348.8 OQR88368.1 - 0.092 12.3 12.9 3.7 7.0 0.3 6.0 7 0 0 7 7 7 0 CLASP N terminal Cation_ATPase_N PF00690.26 OQR88369.1 - 3.5e-15 55.4 0.0 4.3e-15 55.2 0.0 1.1 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus FtsA PF14450.6 OQR88371.1 - 0.064 13.7 0.0 0.094 13.1 0.0 1.2 1 0 0 1 1 1 0 Cell division protein FtsA V-SNARE_C PF12352.8 OQR88372.1 - 1.8e-14 53.7 4.4 3.5e-14 52.8 4.4 1.5 1 0 0 1 1 1 1 Snare region anchored in the vesicle membrane C-terminus V-SNARE PF05008.15 OQR88372.1 - 8.8e-09 35.6 2.6 8.8e-09 35.6 2.6 2.6 3 0 0 3 3 3 1 Vesicle transport v-SNARE protein N-terminus Sec20 PF03908.13 OQR88372.1 - 0.01 15.8 6.2 0.28 11.1 0.2 2.9 2 1 1 3 3 3 0 Sec20 DUF4407 PF14362.6 OQR88372.1 - 0.014 14.8 5.1 0.018 14.4 5.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Synaptobrevin PF00957.21 OQR88372.1 - 8.5 6.2 7.7 3.9 7.3 3.5 2.5 2 1 1 3 3 3 0 Synaptobrevin zf-AN1 PF01428.16 OQR88374.1 - 0.22 11.7 5.1 25 5.2 1.6 3.4 3 1 0 3 3 3 0 AN1-like Zinc finger Peptidase_M41 PF01434.18 OQR88376.1 - 5.6e-64 215.5 0.1 9.3e-64 214.8 0.1 1.4 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 OQR88376.1 - 5.8e-29 101.2 0.0 1.1e-28 100.3 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 OQR88376.1 - 3.6e-09 36.3 0.2 2.2e-08 33.8 0.0 2.4 2 0 0 2 2 2 1 AAA+ lid domain CDP-OH_P_transf PF01066.21 OQR88380.1 - 5e-16 59.2 0.2 1.5e-15 57.7 0.2 1.9 1 0 0 1 1 1 1 CDP-alcohol phosphatidyltransferase Choline_kinase PF01633.20 OQR88381.1 - 3.6e-58 196.7 0.1 4.9e-58 196.2 0.1 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.23 OQR88381.1 - 5.5e-12 46.1 0.0 9.3e-12 45.4 0.0 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.20 OQR88381.1 - 1.8e-05 24.2 0.6 3.4e-05 23.3 0.6 1.4 1 0 0 1 1 1 1 Ecdysteroid kinase DUF1679 PF07914.11 OQR88381.1 - 0.15 10.9 0.1 0.22 10.4 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) Pkinase_Tyr PF07714.17 OQR88382.1 - 1.6e-49 168.5 0.0 2.1e-49 168.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OQR88382.1 - 4.3e-48 164.0 0.0 6.4e-48 163.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 OQR88382.1 - 0.0038 16.1 0.0 0.0065 15.3 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase ThrE PF06738.12 OQR88382.1 - 1.4 8.2 7.8 0.71 9.2 3.9 2.0 2 0 0 2 2 2 0 Putative threonine/serine exporter DNA_pol_A_exo1 PF01612.20 OQR88383.1 - 5e-25 88.2 0.0 1.2e-24 87.0 0.0 1.6 1 0 0 1 1 1 1 3'-5' exonuclease NTP_transf_2 PF01909.23 OQR88383.1 - 3.5e-07 30.4 0.0 1.1e-06 28.8 0.0 1.9 2 0 0 2 2 2 1 Nucleotidyltransferase domain PAP_assoc PF03828.19 OQR88383.1 - 3.4e-05 24.0 0.3 0.00011 22.3 0.3 1.9 1 1 0 1 1 1 1 Cid1 family poly A polymerase Polbeta PF18765.1 OQR88383.1 - 0.00054 20.0 0.0 0.0021 18.1 0.0 2.0 2 0 0 2 2 2 1 Polymerase beta, Nucleotidyltransferase ABC_membrane PF00664.23 OQR88384.1 - 2.6e-35 122.4 14.2 2e-20 73.6 3.4 2.3 2 0 0 2 2 2 2 ABC transporter transmembrane region Ank_2 PF12796.7 OQR88384.1 - 1.5e-20 73.5 3.1 2e-11 44.3 0.7 2.6 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) ABC_tran PF00005.27 OQR88384.1 - 3.7e-13 50.2 0.0 7.5e-13 49.2 0.0 1.5 1 0 0 1 1 1 1 ABC transporter Ank_4 PF13637.6 OQR88384.1 - 9e-11 42.1 0.2 6.2e-10 39.4 0.1 2.5 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 OQR88384.1 - 3.3e-10 40.0 0.6 2.5e-06 27.7 0.0 3.4 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 OQR88384.1 - 8.7e-10 38.6 2.2 9.1e-06 25.9 0.0 3.9 3 0 0 3 3 2 2 Ankyrin repeat Ank_3 PF13606.6 OQR88384.1 - 4.4e-08 32.8 1.7 0.0011 19.3 0.0 4.5 4 0 0 4 4 4 2 Ankyrin repeat SMC_N PF02463.19 OQR88384.1 - 0.012 15.1 0.1 4.1 6.8 0.0 2.2 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain FtsK_SpoIIIE PF01580.18 OQR88384.1 - 0.028 13.8 0.0 0.055 12.8 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family TrwB_AAD_bind PF10412.9 OQR88384.1 - 0.079 11.9 0.0 0.16 10.9 0.0 1.4 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain Dynamin_N PF00350.23 OQR88384.1 - 0.16 12.0 0.0 0.42 10.7 0.0 1.7 1 0 0 1 1 1 0 Dynamin family NPCBM PF08305.11 OQR88385.1 - 3.7e-18 66.0 0.0 7e-18 65.1 0.0 1.5 1 0 0 1 1 1 1 NPCBM/NEW2 domain SPRY PF00622.28 OQR88385.1 - 2.1e-14 53.7 0.0 1.1e-09 38.4 0.0 2.4 2 0 0 2 2 2 2 SPRY domain zf-RanBP PF00641.18 OQR88385.1 - 4.9 6.6 9.2 0.1 12.0 1.2 2.4 3 0 0 3 3 3 0 Zn-finger in Ran binding protein and others Glyco_hydro_31 PF01055.26 OQR88386.1 - 2.2e-87 294.1 13.5 3.3e-87 293.5 13.5 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 DUF5110 PF17137.4 OQR88386.1 - 1.6e-11 44.3 0.7 3.6e-11 43.2 0.2 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF5110) Trefoil PF00088.18 OQR88386.1 - 2.6e-06 27.2 6.3 4.5e-06 26.5 6.3 1.4 1 0 0 1 1 1 1 Trefoil (P-type) domain DUF4968 PF16338.5 OQR88386.1 - 3.4e-05 24.1 0.0 7.4e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4968) Metallopep PF12044.8 OQR88387.1 - 1.5e-69 234.6 0.2 2.2e-69 234.2 0.2 1.1 1 0 0 1 1 1 1 Putative peptidase family Jacalin PF01419.17 OQR88387.1 - 2.7e-14 53.2 0.1 3.2e-09 36.8 0.0 3.4 3 0 0 3 3 3 2 Jacalin-like lectin domain Peptidase_M66 PF10462.9 OQR88387.1 - 0.013 14.5 1.4 0.023 13.7 1.4 1.3 1 0 0 1 1 1 0 Peptidase M66 Peptidase_M10 PF00413.24 OQR88387.1 - 0.015 15.1 0.1 0.029 14.2 0.1 1.4 1 0 0 1 1 1 0 Matrixin Reprolysin_3 PF13582.6 OQR88387.1 - 0.057 13.9 0.4 0.17 12.4 0.4 1.9 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.6 OQR88387.1 - 0.18 11.9 1.4 0.34 11.0 1.4 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12 Nup84_Nup100 PF04121.13 OQR88388.1 - 4e-122 408.8 4.7 6.8e-122 408.0 4.7 1.3 1 1 0 1 1 1 1 Nuclear pore protein 84 / 107 SPATA6 PF14909.6 OQR88388.1 - 0.095 12.8 0.2 0.29 11.2 0.1 1.9 2 0 0 2 2 2 0 Spermatogenesis-assoc protein 6 EamA PF00892.20 OQR88389.1 - 7.9e-25 87.6 37.7 2.5e-12 47.1 13.2 2.1 2 0 0 2 2 2 2 EamA-like transporter family EF-hand_1 PF00036.32 OQR88390.1 - 8.2e-15 53.2 6.3 6.1e-07 28.5 0.2 3.2 3 0 0 3 3 3 3 EF hand EF-hand_7 PF13499.6 OQR88390.1 - 2.8e-13 50.1 5.4 8.4e-08 32.6 1.7 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 OQR88390.1 - 1.9e-12 46.1 6.3 0.00069 19.0 0.2 3.2 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.6 OQR88390.1 - 2.7e-11 42.5 9.4 0.00012 21.7 0.1 3.4 2 1 1 3 3 3 3 EF-hand domain EF-hand_8 PF13833.6 OQR88390.1 - 9.3e-11 41.4 7.8 0.00011 22.0 0.4 3.3 2 2 1 3 3 3 3 EF-hand domain pair SPARC_Ca_bdg PF10591.9 OQR88390.1 - 0.0052 17.1 2.5 1.2 9.5 0.9 2.9 1 1 1 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region PCI PF01399.27 OQR88390.1 - 0.068 13.7 0.3 0.082 13.4 0.3 1.2 1 0 0 1 1 1 0 PCI domain EF-hand_4 PF12763.7 OQR88390.1 - 0.11 12.4 5.3 9.9 6.2 0.1 2.9 1 1 2 3 3 3 0 Cytoskeletal-regulatory complex EF hand Peptidase_C1 PF00112.23 OQR88392.1 - 7.1e-15 55.7 0.5 8.3e-15 55.5 0.5 1.1 1 0 0 1 1 1 1 Papain family cysteine protease Trypan_PARP PF05887.11 OQR88392.1 - 3.3e-05 23.9 7.3 5e-05 23.3 7.3 1.3 1 0 0 1 1 1 1 Procyclic acidic repetitive protein (PARP) cNMP_binding PF00027.29 OQR88394.1 - 3.7e-16 59.0 0.0 7.9e-16 57.9 0.0 1.6 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Cwf_Cwc_15 PF04889.12 OQR88394.1 - 0.0027 17.5 1.4 0.0041 16.9 1.4 1.3 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein GCIP PF13324.6 OQR88394.1 - 0.011 15.4 4.8 0.019 14.6 4.8 1.4 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting Sporozoite_P67 PF05642.11 OQR88394.1 - 0.017 13.3 1.5 0.025 12.7 1.5 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Telethonin PF09470.10 OQR88394.1 - 0.018 14.9 0.1 0.057 13.3 0.0 1.8 2 0 0 2 2 2 0 Telethonin protein CENP-B_dimeris PF09026.10 OQR88394.1 - 0.02 15.2 11.3 0.061 13.7 11.3 1.8 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Sigma70_ner PF04546.13 OQR88394.1 - 0.061 13.2 6.2 0.11 12.3 6.2 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region Pox_Ag35 PF03286.14 OQR88394.1 - 0.078 12.8 3.1 0.14 12.0 3.1 1.4 1 0 0 1 1 1 0 Pox virus Ag35 surface protein KxDL PF10241.9 OQR88394.1 - 0.86 9.9 4.1 7.6 6.9 0.9 2.4 2 0 0 2 2 2 0 Uncharacterized conserved protein NOA36 PF06524.12 OQR88394.1 - 1.2 8.4 11.6 1.9 7.7 11.6 1.2 1 0 0 1 1 1 0 NOA36 protein DNA_pol_phi PF04931.13 OQR88394.1 - 6.4 4.8 11.7 9.1 4.2 11.7 1.2 1 0 0 1 1 1 0 DNA polymerase phi Peptidase_C1 PF00112.23 OQR88395.1 - 3.6e-53 180.9 9.5 5e-53 180.4 9.5 1.2 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.15 OQR88395.1 - 5.1e-05 22.2 2.1 0.0098 14.7 0.4 2.1 2 0 0 2 2 2 2 Peptidase C1-like family MDMPI_N PF11716.8 OQR88395.1 - 0.13 12.9 1.1 0.25 12.0 1.1 1.4 1 0 0 1 1 1 0 Mycothiol maleylpyruvate isomerase N-terminal domain zinc_ribbon_2 PF13240.6 OQR88396.1 - 0.063 13.0 0.9 1.8 8.4 0.1 2.9 2 0 0 2 2 2 0 zinc-ribbon domain Prim_Zn_Ribbon PF08273.12 OQR88396.1 - 0.19 12.0 2.8 7.6 6.9 0.5 2.5 2 0 0 2 2 2 0 Zinc-binding domain of primase-helicase zf-HIT PF04438.16 OQR88396.1 - 0.93 9.4 5.9 0.55 10.2 0.5 2.2 2 0 0 2 2 2 0 HIT zinc finger TNFR_c6 PF00020.18 OQR88396.1 - 1.1 9.7 5.9 1.5 9.3 0.4 2.3 2 0 0 2 2 2 0 TNFR/NGFR cysteine-rich region zf-NADH-PPase PF09297.11 OQR88396.1 - 3.3 7.4 6.2 1.2 8.9 0.6 2.5 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain DHHC PF01529.20 OQR88397.1 - 6.5e-29 100.7 10.3 6.5e-29 100.7 10.3 1.6 2 0 0 2 2 2 1 DHHC palmitoyltransferase EcsB PF05975.12 OQR88397.1 - 0.03 13.2 0.3 0.03 13.2 0.3 1.7 2 0 0 2 2 2 0 Bacterial ABC transporter protein EcsB Aa_trans PF01490.18 OQR88399.1 - 8.7e-43 146.6 21.6 1.1e-42 146.2 21.6 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein TUDOR_5 PF18359.1 OQR88400.1 - 2.8e-17 62.1 18.1 1.2e-06 28.1 0.8 5.5 5 0 0 5 5 5 5 Histone methyltransferase Tudor domain 1 Agenet PF05641.12 OQR88400.1 - 7.7e-08 32.7 9.7 0.19 12.2 0.0 5.4 5 0 0 5 5 5 2 Agenet domain DUF4537 PF15057.6 OQR88400.1 - 7.5e-07 29.2 1.6 1 9.4 0.0 4.8 3 1 1 4 4 4 4 Domain of unknown function (DUF4537) DUF1325 PF07039.11 OQR88400.1 - 6.5e-06 26.3 10.4 0.013 15.5 1.3 4.1 3 1 1 4 4 4 3 SGF29 tudor-like domain EF-hand_6 PF13405.6 OQR88400.1 - 0.011 15.7 0.0 2.8 8.1 0.0 2.7 2 0 0 2 2 2 0 EF-hand domain 53-BP1_Tudor PF09038.10 OQR88400.1 - 0.018 15.0 3.6 1 9.3 0.0 4.2 4 1 1 5 5 5 0 Tumour suppressor p53-binding protein-1 Tudor EF-hand_7 PF13499.6 OQR88400.1 - 0.031 14.7 0.0 0.12 12.9 0.0 2.0 1 1 0 1 1 1 0 EF-hand domain pair LPD30 PF18850.1 OQR88400.1 - 0.044 13.6 0.1 4.8 7.0 0.0 3.1 3 1 0 3 3 3 0 Large polyvalent protein associated domain 30 DZR PF12773.7 OQR88400.1 - 0.14 12.2 7.4 0.034 14.2 1.4 2.3 2 0 0 2 2 2 0 Double zinc ribbon zf-RanBP PF00641.18 OQR88400.1 - 0.17 11.2 14.0 0.68 9.3 2.5 2.7 2 1 0 2 2 2 0 Zn-finger in Ran binding protein and others zf-ribbon_3 PF13248.6 OQR88400.1 - 5.5 6.5 8.4 0.66 9.5 1.1 2.3 2 0 0 2 2 2 0 zinc-ribbon domain Myosin_head PF00063.21 OQR88402.1 - 1.1e-70 238.7 0.0 3e-70 237.3 0.0 1.7 1 0 0 1 1 1 1 Myosin head (motor domain) FYVE PF01363.21 OQR88402.1 - 2.7e-12 46.7 18.6 9.5e-12 44.9 18.6 1.9 1 0 0 1 1 1 1 FYVE zinc finger IQ PF00612.27 OQR88402.1 - 0.00034 20.1 0.2 0.00034 20.1 0.2 5.2 5 0 0 5 5 5 2 IQ calmodulin-binding motif COMM_domain PF07258.14 OQR88402.1 - 0.099 12.8 0.4 0.42 10.8 0.1 2.3 2 0 0 2 2 2 0 COMM domain Acyl-CoA_dh_1 PF00441.24 OQR88406.1 - 1.3e-42 145.5 3.4 4.1e-40 137.4 0.1 2.3 2 0 0 2 2 2 2 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 OQR88406.1 - 1.3e-25 89.4 0.0 2.7e-25 88.4 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 OQR88406.1 - 3.9e-23 82.2 0.0 3.9e-22 79.0 0.0 2.4 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 OQR88406.1 - 7.6e-12 45.6 0.2 2.3e-09 37.7 0.0 2.3 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.8 OQR88406.1 - 0.27 10.9 1.2 1.4 8.5 0.4 2.4 2 1 0 2 2 2 0 4-hydroxyphenylacetate 3-hydroxylase N terminal Ank_2 PF12796.7 OQR88407.1 - 2.1e-15 57.1 1.9 5e-08 33.4 0.0 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQR88407.1 - 1.2e-13 51.3 0.3 3.5e-06 27.4 0.1 3.3 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQR88407.1 - 1.4e-10 40.5 0.1 3.1 8.7 0.0 5.1 5 0 0 5 5 5 4 Ankyrin repeat Ank_5 PF13857.6 OQR88407.1 - 2.9e-10 40.2 1.2 0.12 12.7 0.0 4.9 2 1 3 5 5 5 3 Ankyrin repeats (many copies) DUF5049 PF16468.5 OQR88407.1 - 0.001 18.9 0.1 24 4.9 0.0 4.3 1 1 3 4 4 4 1 Domain of unknown function (DUF5049) Ank PF00023.30 OQR88407.1 - 0.0016 18.8 0.2 36 5.0 0.0 3.9 2 1 1 3 3 3 0 Ankyrin repeat Ank_2 PF12796.7 OQR88408.1 - 1.8e-14 54.1 5.5 2.8e-08 34.2 0.8 2.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OQR88408.1 - 8e-08 32.4 1.7 0.023 15.0 0.0 3.9 2 1 2 4 4 4 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 OQR88408.1 - 7.5e-07 29.6 1.4 7.6e-05 23.2 0.1 3.1 2 1 0 3 3 3 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQR88408.1 - 2.3e-06 27.5 0.5 0.11 13.1 0.0 3.3 2 1 1 3 3 3 2 Ankyrin repeat Ank PF00023.30 OQR88408.1 - 8.9e-05 22.8 0.7 1.2 9.7 0.0 3.0 2 1 0 2 2 2 2 Ankyrin repeat DUF3447 PF11929.8 OQR88408.1 - 0.025 14.5 2.4 2.2 8.3 0.1 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3447) BAP PF06639.11 OQR88408.1 - 0.16 12.3 0.2 6.8 7.1 0.0 2.2 2 0 0 2 2 2 0 Basal layer antifungal peptide (BAP) ADH_zinc_N PF00107.26 OQR88410.1 - 6.7e-05 22.9 0.0 0.00014 21.9 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Orai-1 PF07856.12 OQR88411.1 - 6.9e-37 126.8 14.6 1.9e-28 99.3 2.9 2.1 2 0 0 2 2 2 2 Mediator of CRAC channel activity Jiraiya PF15038.6 OQR88411.1 - 0.00017 21.1 0.6 0.00017 21.1 0.6 2.8 2 1 0 2 2 2 1 Jiraiya DUF2678 PF10856.8 OQR88411.1 - 0.86 9.6 5.6 1.6 8.7 1.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2678) CxxCxxCC PF03692.15 OQR88412.1 - 1.2e-13 51.6 4.4 1.7e-13 51.0 4.4 1.2 1 0 0 1 1 1 1 Putative zinc- or iron-chelating domain DUF3109 PF11307.8 OQR88412.1 - 0.00024 21.0 1.0 0.00036 20.4 1.0 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF3109) PSII_Pbs27 PF13326.6 OQR88412.1 - 0.14 12.4 0.1 0.25 11.7 0.1 1.3 1 0 0 1 1 1 0 Photosystem II Pbs27 SPRY PF00622.28 OQR88413.1 - 5.3e-10 39.5 0.0 1e-09 38.5 0.0 1.4 1 0 0 1 1 1 1 SPRY domain UIM PF02809.20 OQR88413.1 - 0.01 15.7 0.6 0.041 13.8 0.6 2.1 1 0 0 1 1 1 0 Ubiquitin interaction motif Pkinase_Tyr PF07714.17 OQR88416.1 - 4.7e-10 39.2 0.4 3.8e-09 36.2 0.1 2.3 2 1 1 3 3 3 1 Protein tyrosine kinase Pkinase PF00069.25 OQR88416.1 - 8.5e-07 28.6 0.1 2.8e-06 26.9 0.1 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQR88417.1 - 7.4e-22 77.9 2.0 4.1e-12 45.9 0.0 3.1 2 1 1 3 3 3 3 Protein tyrosine kinase Pkinase PF00069.25 OQR88417.1 - 7.6e-20 71.4 2.2 4.2e-11 42.7 0.3 3.2 2 1 0 2 2 2 2 Protein kinase domain Kdo PF06293.14 OQR88417.1 - 0.11 11.8 0.1 4.2 6.7 0.0 2.1 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_Tyr PF07714.17 OQR88418.1 - 8.4e-13 48.2 0.0 1.2e-12 47.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OQR88418.1 - 1.4e-12 47.6 0.0 2e-12 47.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase PF00069.25 OQR88419.1 - 5.7e-20 71.8 0.0 6.5e-20 71.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQR88419.1 - 7.3e-16 58.2 0.0 8.4e-16 58.0 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OQR88419.1 - 0.0051 16.2 0.0 0.0072 15.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_Tyr PF07714.17 OQR88420.1 - 1.3e-34 119.6 0.0 4.8e-21 75.2 0.0 3.0 1 1 2 3 3 3 3 Protein tyrosine kinase Pkinase PF00069.25 OQR88420.1 - 1.3e-30 106.7 0.0 2.4e-17 63.2 0.0 3.0 1 1 2 3 3 3 3 Protein kinase domain MIX PF18529.1 OQR88423.1 - 0.012 15.3 1.2 2.8 7.6 0.0 3.7 2 2 2 4 4 4 0 Mitochondrial membrane-anchored proteins ubiquitin PF00240.23 OQR88423.1 - 0.015 15.0 0.0 15 5.4 0.0 3.7 4 0 0 4 4 4 0 Ubiquitin family Toxin_11 PF07473.11 OQR88423.1 - 0.55 10.4 18.8 1.1 9.4 0.2 5.3 5 0 0 5 5 5 0 Spasmodic peptide gm9a; conotoxin from Conus species Alpha_kinase PF02816.18 OQR88425.1 - 5.9e-32 111.3 0.0 8e-32 110.8 0.0 1.2 1 0 0 1 1 1 1 Alpha-kinase family AAA_13 PF13166.6 OQR88429.1 - 0.0018 17.0 6.2 0.0025 16.5 6.2 1.2 1 0 0 1 1 1 1 AAA domain Fib_alpha PF08702.10 OQR88429.1 - 0.075 13.2 6.6 0.13 12.4 6.6 1.4 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family DUF4407 PF14362.6 OQR88429.1 - 0.14 11.5 7.6 0.22 10.9 7.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Atg14 PF10186.9 OQR88429.1 - 0.14 11.2 10.7 0.22 10.6 10.7 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Cob_adeno_trans PF01923.18 OQR88429.1 - 0.14 12.2 1.0 0.25 11.5 1.0 1.4 1 0 0 1 1 1 0 Cobalamin adenosyltransferase FlaC_arch PF05377.11 OQR88429.1 - 0.15 12.5 6.2 0.11 13.0 1.5 2.9 2 1 1 3 3 2 0 Flagella accessory protein C (FlaC) Adaptin_binding PF10199.9 OQR88429.1 - 0.16 12.6 5.9 2.7 8.6 1.0 2.5 1 1 1 2 2 2 0 Alpha and gamma adaptin binding protein p34 SKA1 PF07160.12 OQR88429.1 - 0.19 11.5 10.1 0.35 10.7 10.1 1.4 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 1 zf-C4H2 PF10146.9 OQR88429.1 - 0.28 11.5 13.7 0.44 10.8 13.0 1.7 1 1 0 1 1 1 0 Zinc finger-containing protein Syntaxin-6_N PF09177.11 OQR88429.1 - 0.39 11.3 6.9 0.64 10.6 6.1 1.8 1 1 0 1 1 1 0 Syntaxin 6, N-terminal HAUS6_N PF14661.6 OQR88429.1 - 0.84 9.2 6.4 1.4 8.5 5.8 1.7 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus Macoilin PF09726.9 OQR88429.1 - 2.3 6.7 12.2 3.3 6.2 12.2 1.1 1 0 0 1 1 1 0 Macoilin family TMPIT PF07851.13 OQR88429.1 - 3.7 6.7 6.4 5.2 6.2 6.4 1.2 1 0 0 1 1 1 0 TMPIT-like protein V_ATPase_I PF01496.19 OQR88429.1 - 8 4.2 6.8 11 3.8 6.8 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family H_PPase PF03030.16 OQR88432.1 - 9.9e-232 771.2 41.3 1.1e-231 771.0 41.3 1.0 1 0 0 1 1 1 1 Inorganic H+ pyrophosphatase TMEM208_SND2 PF05620.11 OQR88432.1 - 0.42 10.4 2.2 12 5.6 0.3 2.5 2 0 0 2 2 2 0 SRP-independent targeting protein 2/TMEM208 4HB_MCP_1 PF12729.7 OQR88434.1 - 0.13 11.8 1.3 3 7.4 0.1 2.4 2 0 0 2 2 2 0 Four helix bundle sensory module for signal transduction Nup35_RRM PF05172.13 OQR88436.1 - 0.0033 17.4 0.3 0.58 10.2 0.0 2.5 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif FANCD2OS PF15124.6 OQR88436.1 - 0.84 9.8 10.4 0.14 12.4 0.6 2.9 1 1 0 2 2 2 0 FANCD2 opposite strand protein CN_hydrolase PF00795.22 OQR88439.1 - 5e-33 114.5 0.0 7.2e-33 114.0 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase NAD_synthase PF02540.17 OQR88439.1 - 1.8e-26 92.8 0.0 4.7e-26 91.4 0.0 1.6 1 1 0 1 1 1 1 NAD synthase Pkinase PF00069.25 OQR88440.1 - 1.7e-95 319.4 0.2 1.5e-50 172.1 0.0 5.1 2 1 2 4 4 4 4 Protein kinase domain Pkinase_Tyr PF07714.17 OQR88440.1 - 1.3e-90 303.2 0.1 6.5e-45 153.4 0.0 5.3 3 1 2 5 5 5 5 Protein tyrosine kinase Pkinase_fungal PF17667.1 OQR88440.1 - 1.1e-06 27.8 0.0 1.1e-06 27.8 0.0 1.8 3 0 0 3 3 3 1 Fungal protein kinase Kinase-like PF14531.6 OQR88440.1 - 1.8e-06 27.5 0.9 0.48 9.7 0.0 4.2 4 0 0 4 4 4 3 Kinase-like Kdo PF06293.14 OQR88440.1 - 2.4e-05 23.8 4.4 0.14 11.5 0.2 4.2 4 0 0 4 4 4 3 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OQR88440.1 - 0.00039 20.4 0.1 0.0028 17.6 0.1 2.2 2 0 0 2 2 2 1 Phosphotransferase enzyme family AP_endonuc_2 PF01261.24 OQR88440.1 - 0.031 13.7 0.0 0.078 12.4 0.0 1.6 2 0 0 2 2 2 0 Xylose isomerase-like TIM barrel Choline_kinase PF01633.20 OQR88440.1 - 0.055 13.1 0.2 21 4.6 0.0 3.2 3 0 0 3 3 3 0 Choline/ethanolamine kinase RIO1 PF01163.22 OQR88440.1 - 0.21 11.2 0.9 1 8.9 0.0 2.2 2 0 0 2 2 2 0 RIO1 family TPR_10 PF13374.6 OQR88441.1 - 7.9e-55 181.4 16.7 5e-11 42.1 0.0 8.3 8 0 0 8 8 8 7 Tetratricopeptide repeat TPR_12 PF13424.6 OQR88441.1 - 1.5e-54 182.2 27.7 4e-15 55.9 0.7 5.1 3 1 2 5 5 5 5 Tetratricopeptide repeat TPR_1 PF00515.28 OQR88441.1 - 3.6e-17 61.4 29.3 0.0094 15.7 0.2 7.5 7 0 0 7 7 7 7 Tetratricopeptide repeat TPR_7 PF13176.6 OQR88441.1 - 8.5e-17 59.9 17.0 0.0018 18.2 0.0 7.6 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_2 PF07719.17 OQR88441.1 - 1.5e-15 56.0 22.3 0.047 13.8 1.8 7.2 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_8 PF13181.6 OQR88441.1 - 4.3e-15 54.6 25.3 0.00032 20.7 0.1 7.4 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_MalT PF17874.1 OQR88441.1 - 1e-11 44.9 5.9 1.3e-07 31.4 3.0 2.4 1 1 1 2 2 2 2 MalT-like TPR region TPR_14 PF13428.6 OQR88441.1 - 2e-07 31.3 6.1 3.1 8.8 0.0 7.0 5 1 2 7 7 7 1 Tetratricopeptide repeat TPR_16 PF13432.6 OQR88441.1 - 5.5e-07 30.1 5.8 1.3 9.8 0.1 6.5 6 1 0 6 6 6 1 Tetratricopeptide repeat TPR_19 PF14559.6 OQR88441.1 - 7.3e-05 23.2 10.3 0.51 10.9 0.2 4.6 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_4 PF07721.14 OQR88441.1 - 0.0001 22.6 0.0 16 6.5 0.0 5.4 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_6 PF13174.6 OQR88441.1 - 0.00011 22.6 11.7 0.13 12.9 0.1 5.5 6 0 0 6 6 6 2 Tetratricopeptide repeat SHNi-TPR PF10516.9 OQR88441.1 - 0.00036 19.9 3.8 0.0017 17.7 0.2 3.6 4 0 0 4 4 4 1 SHNi-TPR RPN6_N PF18055.1 OQR88441.1 - 0.00046 20.5 6.0 0.066 13.6 0.1 3.7 3 1 0 3 3 3 2 26S proteasome regulatory subunit RPN6 N-terminal domain SNAP PF14938.6 OQR88441.1 - 0.0016 17.9 0.4 0.0016 17.9 0.4 2.4 2 1 0 2 2 2 1 Soluble NSF attachment protein, SNAP BBS2_C PF14782.6 OQR88441.1 - 0.016 14.0 0.5 0.025 13.4 0.5 1.3 1 0 0 1 1 1 0 Ciliary BBSome complex subunit 2, C-terminal MIT PF04212.18 OQR88441.1 - 0.19 11.8 0.0 0.19 11.8 0.0 5.1 5 2 2 7 7 7 0 MIT (microtubule interacting and transport) domain TPR_3 PF07720.12 OQR88441.1 - 7.1 6.7 27.1 5.1 7.2 3.0 6.0 7 0 0 7 7 7 0 Tetratricopeptide repeat Internalin_N PF12354.8 OQR88445.1 - 0.01 15.9 0.1 0.044 13.9 0.1 2.0 2 0 0 2 2 2 0 Bacterial adhesion/invasion protein N terminal Ribosomal_L35p PF01632.19 OQR88446.1 - 2.8e-17 62.9 8.5 3.6e-17 62.6 8.5 1.1 1 0 0 1 1 1 1 Ribosomal protein L35 Pyr_redox_2 PF07992.14 OQR88447.1 - 7.9e-17 61.4 0.2 8.8e-17 61.3 0.2 1.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 OQR88447.1 - 0.00088 18.7 0.1 0.00088 18.7 0.1 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO PF01266.24 OQR88447.1 - 0.0068 16.0 0.1 0.0068 16.0 0.1 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 OQR88447.1 - 0.0078 16.4 2.6 0.017 15.4 2.4 1.7 1 1 0 1 1 1 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 OQR88447.1 - 0.0083 15.2 2.3 0.0086 15.2 2.3 1.3 1 1 0 1 1 1 1 Glucose inhibited division protein A FAD_binding_2 PF00890.24 OQR88447.1 - 0.015 14.4 1.9 0.021 13.9 1.9 1.2 1 0 0 1 1 1 0 FAD binding domain HI0933_like PF03486.14 OQR88447.1 - 0.026 13.3 0.4 0.027 13.2 0.4 1.1 1 0 0 1 1 1 0 HI0933-like protein Thi4 PF01946.17 OQR88447.1 - 0.028 13.7 0.2 0.035 13.3 0.2 1.2 1 0 0 1 1 1 0 Thi4 family AlaDh_PNT_C PF01262.21 OQR88447.1 - 0.098 11.9 0.2 0.15 11.3 0.2 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain GSP_synth PF03738.14 OQR88449.1 - 3e-102 342.6 0.0 3.7e-102 342.3 0.0 1.1 1 0 0 1 1 1 1 Glutathionylspermidine synthase preATP-grasp APH_6_hur PF04655.14 OQR88449.1 - 0.047 13.1 0.0 0.083 12.3 0.0 1.3 1 0 0 1 1 1 0 Aminoglycoside/hydroxyurea antibiotic resistance kinase HNOBA PF07701.14 OQR88449.1 - 0.091 12.2 0.0 0.24 10.8 0.0 1.7 2 0 0 2 2 2 0 Heme NO binding associated Pkinase PF00069.25 OQR88450.1 - 1.2e-55 188.8 0.5 6.2e-55 186.4 0.5 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQR88450.1 - 2.2e-31 109.1 0.2 3.1e-31 108.6 0.2 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OQR88450.1 - 0.00099 18.5 0.1 0.0027 17.1 0.1 1.6 1 1 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 OQR88450.1 - 0.0041 16.0 0.0 0.0065 15.3 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase YrbL-PhoP_reg PF10707.9 OQR88450.1 - 0.052 13.1 0.0 0.089 12.3 0.0 1.4 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Kdo PF06293.14 OQR88450.1 - 0.07 12.5 0.7 0.12 11.8 0.7 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Paramyx_P_V_C PF03210.13 OQR88450.1 - 0.07 12.9 0.0 0.36 10.6 0.0 1.9 2 0 0 2 2 2 0 Paramyxovirus P/V phosphoprotein C-terminal APH PF01636.23 OQR88450.1 - 0.089 12.7 0.0 0.21 11.5 0.1 1.5 1 1 0 1 1 1 0 Phosphotransferase enzyme family cNMP_binding PF00027.29 OQR88452.1 - 4.2e-15 55.6 0.0 7.8e-15 54.7 0.0 1.5 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Ion_trans PF00520.31 OQR88452.1 - 9.5e-11 41.4 9.6 1.7e-10 40.6 9.6 1.4 1 1 0 1 1 1 1 Ion transport protein KOW PF00467.29 OQR88452.1 - 0.035 14.1 0.2 0.19 11.8 0.0 2.2 2 0 0 2 2 2 0 KOW motif Nbl1_Borealin_N PF10444.9 OQR88452.1 - 0.24 11.1 4.9 22 4.8 0.1 3.6 3 0 0 3 3 3 0 Nbl1 / Borealin N terminal TRM PF02005.16 OQR88453.1 - 4.3e-71 240.1 0.3 6.1e-71 239.6 0.3 1.2 1 0 0 1 1 1 1 N2,N2-dimethylguanosine tRNA methyltransferase Beta_helix PF13229.6 OQR88453.1 - 9.4e-40 136.0 46.5 1.5e-19 70.4 8.7 3.0 1 1 2 3 3 3 3 Right handed beta helix region NosD PF05048.13 OQR88453.1 - 4.1e-16 59.0 16.0 1e-12 47.9 3.0 2.8 1 1 2 3 3 3 3 Periplasmic copper-binding protein (NosD) Met_10 PF02475.16 OQR88453.1 - 8.2e-06 25.7 0.2 1.8e-05 24.5 0.2 1.6 1 0 0 1 1 1 1 Met-10+ like-protein PrmA PF06325.13 OQR88453.1 - 0.00063 19.2 0.9 0.0014 18.1 0.8 1.6 1 1 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_15 PF09445.10 OQR88453.1 - 0.0073 15.9 0.9 0.015 14.9 0.1 1.9 2 0 0 2 2 2 1 RNA cap guanine-N2 methyltransferase Cons_hypoth95 PF03602.15 OQR88453.1 - 0.013 15.2 0.0 0.024 14.3 0.0 1.4 1 0 0 1 1 1 0 Conserved hypothetical protein 95 MTS PF05175.14 OQR88453.1 - 0.021 14.4 0.1 0.047 13.2 0.1 1.5 1 0 0 1 1 1 0 Methyltransferase small domain CTK3 PF12243.8 OQR88453.1 - 0.14 12.2 0.1 0.52 10.3 0.1 1.9 2 0 0 2 2 2 0 CTD kinase subunit gamma CTK3 ABC2_membrane PF01061.24 OQR88454.1 - 1.6e-14 53.8 18.6 1.6e-14 53.8 18.6 1.7 2 0 0 2 2 2 1 ABC-2 type transporter PDR_assoc PF08370.11 OQR88454.1 - 1.4e-07 31.1 1.2 1.4e-07 31.1 1.2 2.4 3 0 0 3 3 3 1 Plant PDR ABC transporter associated ABC2_membrane_3 PF12698.7 OQR88454.1 - 0.00089 18.5 10.9 0.00089 18.5 10.9 1.7 1 1 1 2 2 2 1 ABC-2 family transporter protein MRP_L53 PF10780.9 OQR88454.1 - 0.015 15.4 0.1 0.027 14.6 0.1 1.4 1 0 0 1 1 1 0 39S ribosomal protein L53/MRP-L53 FYVE PF01363.21 OQR88455.1 - 1.4e-07 31.5 17.9 1.4e-07 31.5 17.9 1.9 3 0 0 3 3 3 1 FYVE zinc finger DUF2496 PF10689.9 OQR88455.1 - 0.049 13.4 0.1 0.17 11.7 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2496) FYVE_2 PF02318.16 OQR88455.1 - 0.74 10.0 14.1 0.15 12.3 10.2 1.8 2 0 0 2 2 2 0 FYVE-type zinc finger CH PF00307.31 OQR88457.1 - 6.4e-12 45.6 0.1 1.7e-11 44.3 0.1 1.7 1 0 0 1 1 1 1 Calponin homology (CH) domain DUF3138 PF11336.8 OQR88457.1 - 0.019 13.6 1.6 0.035 12.7 1.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) DUF5082 PF16888.5 OQR88457.1 - 0.59 10.4 3.8 0.74 10.1 0.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF5082) DUF1664 PF07889.12 OQR88457.1 - 8.9 6.4 8.6 1.3 9.1 3.2 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) XRCC1_N PF01834.16 OQR88458.1 - 0.12 12.4 0.0 0.19 11.7 0.0 1.3 1 0 0 1 1 1 0 XRCC1 N terminal domain MFS_1 PF07690.16 OQR88459.1 - 8e-33 113.8 30.5 1.1e-32 113.3 30.5 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily OATP PF03137.20 OQR88459.1 - 4.3e-29 101.2 10.3 6.5e-22 77.5 1.8 3.2 1 1 1 2 2 2 2 Organic Anion Transporter Polypeptide (OATP) family Sugar_tr PF00083.24 OQR88459.1 - 3.9e-12 45.8 25.6 5.9e-11 41.9 25.6 2.2 1 1 0 1 1 1 1 Sugar (and other) transporter RCC1 PF00415.18 OQR88460.1 - 1.8e-46 156.5 4.3 7.1e-10 39.4 0.0 6.8 6 0 0 6 6 6 4 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 OQR88460.1 - 1.3e-21 75.8 24.8 2.5e-09 36.7 0.2 6.3 6 0 0 6 6 6 3 Regulator of chromosome condensation (RCC1) repeat Ank_2 PF12796.7 OQR88460.1 - 1.5e-14 54.4 8.2 0.00024 21.7 0.0 3.7 3 0 0 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQR88460.1 - 9.1e-13 48.5 7.5 0.00066 20.2 0.1 4.7 4 0 0 4 4 4 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 OQR88460.1 - 1.9e-08 34.4 12.4 0.65 10.4 0.0 7.4 2 2 4 7 7 7 4 Ankyrin repeats (many copies) PA PF02225.22 OQR88460.1 - 0.00014 21.8 0.0 0.065 13.3 0.0 2.6 2 0 0 2 2 2 2 PA domain Ank_3 PF13606.6 OQR88460.1 - 0.00025 21.2 6.4 51 4.9 0.1 7.1 7 0 0 7 7 7 0 Ankyrin repeat IQ PF00612.27 OQR88460.1 - 0.1 12.5 1.3 0.37 10.7 1.3 2.0 1 0 0 1 1 1 0 IQ calmodulin-binding motif NIF PF03031.18 OQR88462.1 - 0.0045 16.8 0.4 0.017 14.9 0.0 2.2 2 0 0 2 2 2 1 NLI interacting factor-like phosphatase Acid_PPase PF12689.7 OQR88462.1 - 0.44 10.4 5.0 5.5 6.8 0.6 3.5 3 1 0 3 3 3 0 Acid Phosphatase DUF2207 PF09972.9 OQR88463.1 - 0.0032 16.3 0.5 0.004 16.0 0.5 1.1 1 0 0 1 1 1 1 Predicted membrane protein (DUF2207) DUF247 PF03140.15 OQR88463.1 - 0.11 11.7 0.0 0.15 11.2 0.0 1.1 1 0 0 1 1 1 0 Plant protein of unknown function Choline_transpo PF04515.12 OQR88464.1 - 4.2e-81 272.7 31.8 4.2e-81 272.7 31.8 2.7 3 0 0 3 3 3 1 Plasma-membrane choline transporter TetR_C_27 PF17935.1 OQR88464.1 - 0.13 12.3 0.0 0.27 11.3 0.0 1.4 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain Gpi1 PF05024.15 OQR88469.1 - 1.1e-47 162.5 8.7 2.3e-47 161.5 8.7 1.5 1 0 0 1 1 1 1 N-acetylglucosaminyl transferase component (Gpi1) SIR2 PF02146.17 OQR88470.1 - 0.00096 19.1 0.0 0.4 10.6 0.0 3.1 1 1 1 2 2 2 2 Sir2 family NRBF2 PF08961.10 OQR88470.1 - 0.0033 17.0 0.2 0.0061 16.2 0.2 1.4 1 0 0 1 1 1 1 Nuclear receptor-binding factor 2, autophagy regulator KELK PF15796.5 OQR88470.1 - 0.047 14.1 3.6 0.17 12.3 0.5 2.6 2 0 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase ATG16 PF08614.11 OQR88470.1 - 0.34 11.1 4.7 0.32 11.2 0.7 2.1 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) TMF_DNA_bd PF12329.8 OQR88470.1 - 0.41 10.7 3.6 0.44 10.6 0.3 2.3 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding BRCT PF00533.26 OQR88472.1 - 1.3e-23 83.2 0.1 2.7e-11 43.7 0.0 2.7 2 0 0 2 2 2 2 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 OQR88472.1 - 2.1e-11 43.6 0.4 5.6e-08 32.6 0.2 2.7 2 0 0 2 2 2 2 twin BRCT domain DNA_ligase_A_M PF01068.21 OQR88472.1 - 4e-11 42.9 0.0 1.3e-10 41.3 0.0 1.8 1 1 0 1 1 1 1 ATP dependent DNA ligase domain BRCT_2 PF16589.5 OQR88472.1 - 3.6e-09 36.9 0.2 0.0014 19.0 0.0 2.4 2 0 0 2 2 2 2 BRCT domain, a BRCA1 C-terminus domain Hydrolase_4 PF12146.8 OQR88473.1 - 0.003 16.9 0.0 0.0086 15.4 0.0 1.8 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 OQR88473.1 - 0.004 16.8 0.1 0.0063 16.2 0.1 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold MaoC_dehydrat_N PF13452.6 OQR88473.1 - 0.09 12.9 0.0 0.19 11.9 0.0 1.5 1 0 0 1 1 1 0 N-terminal half of MaoC dehydratase PARG_cat PF05028.14 OQR88478.1 - 0.079 12.2 3.0 1.6 8.0 0.2 2.1 2 0 0 2 2 2 0 Poly (ADP-ribose) glycohydrolase (PARG) RAMP PF04901.13 OQR88478.1 - 0.24 11.4 1.1 16 5.5 0.0 2.1 2 0 0 2 2 2 0 Receptor activity modifying family DUF4419 PF14388.6 OQR88479.1 - 1.7e-38 132.7 1.0 3e-38 132.0 1.0 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF4419) EamA PF00892.20 OQR88480.1 - 9.4e-19 67.9 39.0 2.5e-09 37.4 13.8 2.1 2 0 0 2 2 2 2 EamA-like transporter family SLC35F PF06027.12 OQR88480.1 - 1.6e-07 31.1 6.1 1.6e-07 31.1 6.1 2.1 1 1 0 2 2 2 1 Solute carrier family 35 PUNUT PF16913.5 OQR88480.1 - 0.00014 21.2 8.3 0.00014 21.2 8.3 2.1 2 0 0 2 2 2 1 Purine nucleobase transmembrane transport TPT PF03151.16 OQR88480.1 - 0.0015 17.9 9.6 0.0037 16.7 9.5 1.7 1 1 0 1 1 1 1 Triose-phosphate Transporter family Sugar_transport PF06800.12 OQR88480.1 - 0.03 13.6 12.0 0.061 12.6 2.3 3.3 2 2 0 2 2 2 0 Sugar transport protein UNC-50 PF05216.13 OQR88480.1 - 0.85 9.1 13.7 0.021 14.4 5.1 2.3 2 0 0 2 2 2 0 UNC-50 family DUF3955 PF13127.6 OQR88480.1 - 2.4 8.0 12.4 0.053 13.3 1.2 3.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3955) Glyco_transf_22 PF03901.17 OQR88481.1 - 1.6e-96 324.1 17.6 1.8e-96 323.9 17.6 1.0 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family PrgI PF12666.7 OQR88481.1 - 7 7.4 8.4 58 4.5 0.1 3.1 1 1 1 2 2 2 0 PrgI family protein WD40 PF00400.32 OQR88482.1 - 7.2e-40 134.2 11.1 5.8e-14 52.3 0.5 6.4 6 0 0 6 6 6 5 WD domain, G-beta repeat Katanin_con80 PF13925.6 OQR88482.1 - 5.1e-20 72.1 0.0 8.6e-20 71.4 0.0 1.3 1 0 0 1 1 1 1 con80 domain of Katanin ANAPC4_WD40 PF12894.7 OQR88482.1 - 4.1e-14 52.6 0.1 9.1e-08 32.3 0.0 3.9 1 1 3 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 OQR88482.1 - 4.8e-08 33.1 1.3 1.3e-05 25.2 0.1 2.4 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A Nucleoporin_N PF08801.11 OQR88482.1 - 3.2e-06 26.1 1.8 0.3 9.8 0.0 3.7 1 1 2 3 3 3 3 Nup133 N terminal like Nup160 PF11715.8 OQR88482.1 - 5.2e-05 22.1 1.7 0.12 11.0 0.1 2.9 1 1 2 3 3 3 3 Nucleoporin Nup120/160 WD40_like PF17005.5 OQR88482.1 - 0.00042 19.7 0.0 0.0056 16.1 0.0 2.2 1 1 1 2 2 2 1 WD40-like domain Cytochrom_D1 PF02239.16 OQR88482.1 - 0.00056 18.6 0.0 0.00092 17.8 0.0 1.3 1 0 0 1 1 1 1 Cytochrome D1 heme domain Ge1_WD40 PF16529.5 OQR88482.1 - 0.00097 18.2 2.7 0.23 10.4 0.2 3.8 2 1 2 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein RRM_1 PF00076.22 OQR88483.1 - 1.2e-22 79.5 0.0 1.7e-22 79.0 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 OQR88483.1 - 0.005 16.7 0.0 0.0066 16.3 0.0 1.1 1 0 0 1 1 1 1 Occluded RNA-recognition motif RRM_5 PF13893.6 OQR88483.1 - 0.0099 15.5 0.0 0.014 15.0 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 OQR88483.1 - 0.03 14.4 0.0 0.059 13.5 0.0 1.5 1 1 0 1 1 1 0 RNA recognition motif SET_assoc PF11767.8 OQR88483.1 - 0.066 12.9 0.0 0.1 12.3 0.0 1.2 1 0 0 1 1 1 0 Histone lysine methyltransferase SET associated Pyridoxal_deC PF00282.19 OQR88484.1 - 1.2e-05 24.2 0.0 0.003 16.3 0.0 2.0 1 1 1 2 2 2 2 Pyridoxal-dependent decarboxylase conserved domain SNF2_N PF00176.23 OQR88485.1 - 2.1e-55 187.8 0.3 3.4e-55 187.2 0.3 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 OQR88485.1 - 4e-20 72.2 0.0 5e-19 68.7 0.0 2.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 OQR88485.1 - 2.8e-08 33.9 0.4 1.1e-07 32.0 0.0 2.2 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 OQR88485.1 - 9.1e-06 25.0 0.4 0.0079 15.4 0.0 2.7 2 1 0 2 2 2 2 Class II histone deacetylase complex subunits 2 and 3 DEAD PF00270.29 OQR88485.1 - 2.1e-05 24.3 0.0 4.5e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase ERCC3_RAD25_C PF16203.5 OQR88485.1 - 0.0006 19.1 0.0 0.003 16.8 0.0 2.2 1 1 1 2 2 2 1 ERCC3/RAD25/XPB C-terminal helicase RabGAP-TBC PF00566.18 OQR88486.1 - 1.6e-56 191.4 0.9 2.4e-56 190.8 0.9 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain CSN8_PSD8_EIF3K PF10075.9 OQR88486.1 - 5.8e-19 68.5 0.0 1.6e-18 67.0 0.0 1.8 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family PDZ PF00595.24 OQR88486.1 - 0.0057 17.0 0.0 0.013 15.9 0.0 1.6 1 0 0 1 1 1 1 PDZ domain PCI PF01399.27 OQR88486.1 - 0.022 15.2 0.0 0.075 13.5 0.0 1.9 1 0 0 1 1 1 0 PCI domain PDZ_6 PF17820.1 OQR88486.1 - 0.071 13.0 0.0 0.32 10.9 0.0 2.2 2 0 0 2 2 2 0 PDZ domain Ion_trans PF00520.31 OQR88488.1 - 7.2e-07 28.7 26.8 1.8e-06 27.4 26.8 1.6 1 1 0 1 1 1 1 Ion transport protein PKD_channel PF08016.12 OQR88488.1 - 4e-06 25.8 12.3 4e-06 25.8 12.3 1.9 1 1 1 2 2 2 1 Polycystin cation channel UPF0242 PF06785.11 OQR88488.1 - 0.021 14.9 3.7 0.056 13.5 3.7 1.7 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus ZapB PF06005.12 OQR88488.1 - 0.03 14.8 5.3 0.058 13.9 5.3 1.4 1 0 0 1 1 1 0 Cell division protein ZapB HALZ PF02183.18 OQR88488.1 - 0.1 12.9 3.1 0.13 12.5 0.8 2.3 2 1 1 3 3 2 0 Homeobox associated leucine zipper DUF4168 PF13767.6 OQR88488.1 - 0.13 13.5 2.1 0.52 11.5 2.1 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4168) ApoO PF09769.9 OQR88488.1 - 0.13 12.2 0.8 0.37 10.8 0.2 1.9 2 0 0 2 2 2 0 Apolipoprotein O DUF1640 PF07798.11 OQR88488.1 - 0.2 11.7 7.3 0.38 10.8 7.3 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1640) bZIP_1 PF00170.21 OQR88488.1 - 0.34 11.0 4.8 0.22 11.7 2.2 1.9 1 1 1 2 2 2 0 bZIP transcription factor Fzo_mitofusin PF04799.13 OQR88488.1 - 1.2 8.6 7.6 2.1 7.9 3.3 2.2 2 0 0 2 2 2 0 fzo-like conserved region SlyX PF04102.12 OQR88488.1 - 2.6 8.7 6.5 2.3 8.9 3.7 2.3 2 1 1 3 3 3 0 SlyX Ank_4 PF13637.6 OQR88489.1 - 2.4e-05 24.8 0.2 0.00021 21.7 0.0 2.6 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 OQR88489.1 - 3.6e-05 24.3 0.0 0.00013 22.5 0.0 1.9 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) DHHC PF01529.20 OQR88489.1 - 0.0014 18.7 1.9 0.0014 18.7 1.9 4.6 2 1 1 3 3 3 1 DHHC palmitoyltransferase Ank_3 PF13606.6 OQR88489.1 - 0.0042 17.5 0.0 0.9 10.3 0.0 3.3 3 0 0 3 3 3 1 Ankyrin repeat Ank_5 PF13857.6 OQR88489.1 - 0.0076 16.5 0.0 0.035 14.4 0.0 2.1 1 1 1 2 2 2 1 Ankyrin repeats (many copies) DUF4064 PF13273.6 OQR88489.1 - 6.7 7.1 11.6 2.3 8.5 0.6 3.7 3 1 0 3 3 3 0 Protein of unknown function (DUF4064) CBM_1 PF00734.18 OQR88491.1 - 6.4e-09 35.6 14.3 6.4e-09 35.6 14.3 3.0 3 1 0 3 3 3 1 Fungal cellulose binding domain DPBB_1 PF03330.18 OQR88491.1 - 0.0011 19.2 0.2 0.0011 19.2 0.2 1.9 2 0 0 2 2 2 1 Lytic transglycolase PT PF04886.12 OQR88491.1 - 0.016 14.8 18.1 0.016 14.8 18.1 3.7 1 1 1 2 2 2 0 PT repeat DUF4106 PF13388.6 OQR88491.1 - 1.9 7.7 17.9 2.8 7.1 17.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) Cation_ATPase_C PF00689.21 OQR88492.1 - 4.9e-51 173.0 1.3 8e-51 172.3 1.3 1.3 1 0 0 1 1 1 1 Cation transporting ATPase, C-terminus ATP_Ca_trans_C PF12424.8 OQR88492.1 - 1.8e-05 25.1 0.7 7.2e-05 23.2 0.7 2.0 1 0 0 1 1 1 1 Plasma membrane calcium transporter ATPase C terminal Hydrolase PF00702.26 OQR88492.1 - 0.00032 21.1 0.0 0.0016 18.7 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 OQR88492.1 - 0.00066 19.5 0.1 0.0014 18.4 0.1 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase SDF PF00375.18 OQR88494.1 - 8.9e-18 64.5 5.7 9.7e-18 64.4 5.7 1.0 1 0 0 1 1 1 1 Sodium:dicarboxylate symporter family SCAI PF12070.8 OQR88494.1 - 0.022 13.6 0.0 0.022 13.6 0.0 1.1 1 0 0 1 1 1 0 Protein SCAI DSPc PF00782.20 OQR88495.1 - 8.8e-36 122.7 0.4 1.6e-35 121.8 0.4 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Glyco_hydro_18 PF00704.28 OQR88495.1 - 5.2e-20 72.4 0.1 1.1e-19 71.4 0.1 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Y_phosphatase PF00102.27 OQR88495.1 - 0.00026 20.6 0.0 0.00043 19.9 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Init_tRNA_PT PF04179.12 OQR88495.1 - 0.025 14.9 0.0 0.054 13.8 0.0 1.5 1 0 0 1 1 1 0 Rit1 DUSP-like domain PTPlike_phytase PF14566.6 OQR88495.1 - 0.026 14.6 0.1 0.05 13.7 0.1 1.4 1 0 0 1 1 1 0 Inositol hexakisphosphate Cadherin_C_2 PF16492.5 OQR88495.1 - 0.23 12.3 1.7 0.29 11.9 0.3 1.8 2 0 0 2 2 2 0 Cadherin cytoplasmic C-terminal Ank_2 PF12796.7 OQR88497.1 - 4.2e-05 24.0 1.3 0.0092 16.6 0.2 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQR88497.1 - 0.0057 17.2 0.1 0.11 13.1 0.0 2.6 2 0 0 2 2 2 1 Ankyrin repeats (many copies) DUF3447 PF11929.8 OQR88497.1 - 0.031 14.2 0.7 7.7 6.6 0.4 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF3447) Ank_3 PF13606.6 OQR88497.1 - 0.039 14.5 0.2 9.6 7.2 0.0 3.5 3 0 0 3 3 3 0 Ankyrin repeat Ank_5 PF13857.6 OQR88497.1 - 0.044 14.1 0.1 16 5.9 0.0 2.5 1 1 1 2 2 2 0 Ankyrin repeats (many copies) Pkinase_Tyr PF07714.17 OQR88498.1 - 4.4e-49 167.1 0.2 6.5e-49 166.5 0.2 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OQR88498.1 - 3.3e-45 154.5 0.1 4.2e-45 154.2 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Haspin_kinase PF12330.8 OQR88498.1 - 0.00031 19.8 0.1 0.0023 16.9 0.1 2.0 1 1 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 OQR88498.1 - 0.0017 17.2 0.0 0.0028 16.5 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 OQR88498.1 - 0.042 13.8 0.0 0.064 13.2 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family WD40 PF00400.32 OQR88499.1 - 3e-11 43.7 9.6 0.033 15.1 0.0 6.7 6 0 0 6 6 6 3 WD domain, G-beta repeat TPR_12 PF13424.6 OQR88499.1 - 8.7e-10 38.8 9.5 2e-07 31.2 0.5 3.2 1 1 1 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 OQR88499.1 - 1e-09 37.7 2.7 0.0034 17.4 0.0 3.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 OQR88499.1 - 2.8e-08 33.3 1.4 0.22 11.8 0.2 4.3 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_1 PF00515.28 OQR88499.1 - 1.8e-07 30.7 2.9 0.1 12.5 0.0 4.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 OQR88499.1 - 3e-06 26.9 2.1 0.34 11.1 0.0 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat LysM PF01476.20 OQR88499.1 - 1.2e-05 25.2 0.3 3.2e-05 23.9 0.0 1.9 2 0 0 2 2 1 1 LysM domain TPR_MalT PF17874.1 OQR88499.1 - 3.3e-05 23.4 5.1 6e-05 22.6 3.9 1.9 1 1 1 2 2 2 1 MalT-like TPR region TPR_19 PF14559.6 OQR88499.1 - 4.9e-05 23.8 2.1 0.0085 16.6 0.2 2.9 2 1 1 3 3 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 OQR88499.1 - 0.0024 18.5 0.8 0.34 11.6 0.3 2.5 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.6 OQR88499.1 - 0.0056 16.3 0.3 4.5 7.0 0.1 3.3 3 0 0 3 3 3 1 TPR repeat TPR_14 PF13428.6 OQR88499.1 - 0.0083 16.9 2.4 8 7.6 0.0 3.8 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_10 PF13374.6 OQR88499.1 - 0.0089 15.9 2.0 0.026 14.4 0.0 2.8 3 0 0 3 3 3 1 Tetratricopeptide repeat FAA_hydro_N_2 PF18288.1 OQR88499.1 - 0.094 13.1 0.5 1.2 9.6 0.1 3.0 3 0 0 3 3 2 0 Fumarylacetoacetase N-terminal domain 2 ANAPC3 PF12895.7 OQR88499.1 - 0.21 11.9 4.2 6.3 7.1 0.5 3.1 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 SAM_KSR1 PF13543.6 OQR88499.1 - 0.44 10.7 3.5 6.2 7.0 0.7 3.5 2 1 1 3 3 3 0 SAM like domain present in kinase suppressor RAS 1 Baculo_PEP_C PF04513.12 OQR88499.1 - 1.8 8.6 8.4 0.33 11.0 0.4 3.2 3 1 1 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus Trns_repr_metal PF02583.17 OQR88499.1 - 3.6 8.0 8.9 0.4 11.1 0.5 3.1 3 0 0 3 3 3 0 Metal-sensitive transcriptional repressor ABC2_membrane PF01061.24 OQR88502.1 - 1.8e-35 122.3 20.1 2.6e-35 121.8 20.1 1.2 1 0 0 1 1 1 1 ABC-2 type transporter DUF1899 PF08953.11 OQR88502.1 - 0.17 11.8 0.1 2.3 8.2 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1899) DUF2085 PF09858.9 OQR88503.1 - 0.016 15.6 3.9 0.43 11.1 2.0 2.4 2 0 0 2 2 2 0 Predicted membrane protein (DUF2085) Glyco_hydro_18 PF00704.28 OQR88506.1 - 1.3e-157 524.4 19.1 5.4e-81 272.7 5.3 2.1 2 0 0 2 2 2 2 Glycosyl hydrolases family 18 Com_YlbF PF06133.11 OQR88507.1 - 0.11 13.1 3.0 0.23 12.1 3.0 1.5 1 0 0 1 1 1 0 Control of competence regulator ComK, YlbF/YmcA FapA PF03961.13 OQR88507.1 - 1.5 7.3 3.2 2.1 6.8 3.2 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A adh_short PF00106.25 OQR88508.1 - 3.2e-50 170.3 0.9 4e-50 170.0 0.9 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OQR88508.1 - 1.4e-33 116.4 0.0 1.7e-33 116.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OQR88508.1 - 1.3e-09 38.2 1.9 3e-09 37.0 1.9 1.5 1 1 0 1 1 1 1 KR domain THF_DHG_CYH_C PF02882.19 OQR88508.1 - 0.00054 19.3 0.4 0.00092 18.6 0.4 1.4 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Epimerase PF01370.21 OQR88508.1 - 0.0025 17.3 0.1 0.0037 16.7 0.1 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family TrkA_N PF02254.18 OQR88508.1 - 0.024 14.9 0.0 0.048 13.9 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain Ldh_1_N PF00056.23 OQR88508.1 - 0.049 13.7 0.6 0.09 12.9 0.6 1.4 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain Syndecan PF01034.20 OQR88510.1 - 0.0011 18.8 0.0 0.0021 17.9 0.0 1.4 1 0 0 1 1 1 1 Syndecan domain Insulin_TMD PF17870.1 OQR88510.1 - 0.035 14.2 0.3 0.11 12.6 0.3 1.8 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment LRR_8 PF13855.6 OQR88510.1 - 3.9 7.3 12.7 11 5.8 1.9 3.4 1 1 3 4 4 4 0 Leucine rich repeat ABC2_membrane PF01061.24 OQR88512.1 - 3.5e-34 118.1 26.1 5.4e-34 117.5 26.1 1.3 1 0 0 1 1 1 1 ABC-2 type transporter PDR_CDR PF06422.12 OQR88512.1 - 0.00075 19.3 0.1 0.00075 19.3 0.1 2.4 2 0 0 2 2 2 1 CDR ABC transporter ABC2_membrane PF01061.24 OQR88513.1 - 7.2e-33 113.8 24.8 1.2e-32 113.0 24.8 1.4 1 0 0 1 1 1 1 ABC-2 type transporter PDR_CDR PF06422.12 OQR88513.1 - 6e-06 26.1 0.3 6e-06 26.1 0.3 2.6 3 0 0 3 3 3 1 CDR ABC transporter PDR_assoc PF08370.11 OQR88513.1 - 0.045 13.5 0.3 0.045 13.5 0.3 3.0 2 1 1 3 3 3 0 Plant PDR ABC transporter associated ADH_zinc_N PF00107.26 OQR88515.1 - 0.00033 20.6 0.2 0.00055 19.9 0.2 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Eno-Rase_NADH_b PF12242.8 OQR88515.1 - 0.045 13.5 0.3 0.1 12.3 0.2 1.6 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase PAN_4 PF14295.6 OQR88516.1 - 2e-22 78.8 26.9 2.7e-11 43.2 3.9 3.5 3 0 0 3 3 3 3 PAN domain PAN_1 PF00024.26 OQR88516.1 - 3.1e-17 62.3 16.0 1.8e-07 31.0 1.8 3.3 1 1 2 3 3 3 3 PAN domain PAN_2 PF08276.11 OQR88516.1 - 0.0051 16.9 23.6 0.47 10.6 4.6 3.3 3 0 0 3 3 3 3 PAN-like domain PAN_3 PF08277.12 OQR88516.1 - 0.058 13.2 20.2 0.23 11.3 1.5 3.4 3 0 0 3 3 3 0 PAN-like domain SpoIIE PF07228.12 OQR88517.1 - 8.2e-10 38.9 0.0 1.8e-09 37.8 0.0 1.5 1 0 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C PF00481.21 OQR88517.1 - 0.00011 21.9 0.0 0.031 13.9 0.0 2.5 2 0 0 2 2 2 2 Protein phosphatase 2C IKBKB_SDD PF18397.1 OQR88517.1 - 0.045 13.0 4.9 0.075 12.3 4.9 1.3 1 0 0 1 1 1 0 IQBAL scaffold dimerization domain TRAF_BIRC3_bd PF16673.5 OQR88517.1 - 0.1 12.4 0.8 0.27 11.0 0.8 1.8 1 0 0 1 1 1 0 TNF receptor-associated factor BIRC3 binding domain BST2 PF16716.5 OQR88517.1 - 6.4 7.4 9.8 20 5.8 5.3 2.6 1 1 1 2 2 2 0 Bone marrow stromal antigen 2 HECT PF00632.25 OQR88519.1 - 2.4e-34 119.2 0.0 4.2e-34 118.4 0.0 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) zf-RanBP PF00641.18 OQR88519.1 - 0.012 14.9 2.4 0.027 13.8 2.4 1.5 1 0 0 1 1 1 0 Zn-finger in Ran binding protein and others Vps36-NZF-N PF16988.5 OQR88519.1 - 0.068 12.6 3.6 0.15 11.5 3.6 1.5 1 0 0 1 1 1 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain Aha1_N PF09229.11 OQR88521.1 - 0.028 14.6 0.1 0.036 14.3 0.1 1.1 1 0 0 1 1 1 0 Activator of Hsp90 ATPase, N-terminal TGT PF01702.18 OQR88522.1 - 2.9e-108 362.1 0.0 1.8e-106 356.2 0.0 2.0 1 1 0 1 1 1 1 Queuine tRNA-ribosyltransferase Pkinase_Tyr PF07714.17 OQR88523.1 - 4e-52 177.1 0.0 5.6e-52 176.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OQR88523.1 - 7.6e-49 166.4 0.0 1.2e-48 165.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 OQR88523.1 - 0.0045 16.3 0.0 0.018 14.4 0.0 1.8 2 0 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 OQR88523.1 - 0.026 13.5 0.0 0.067 12.1 0.0 1.6 1 0 0 1 1 1 0 Haspin like kinase domain Pkinase_fungal PF17667.1 OQR88523.1 - 0.044 12.5 0.1 0.088 11.6 0.1 1.4 1 0 0 1 1 1 0 Fungal protein kinase APH PF01636.23 OQR88523.1 - 0.049 13.5 0.0 0.087 12.7 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family BaxI_1 PF12811.7 OQR88523.1 - 0.18 11.4 5.6 0.097 12.2 3.3 1.6 1 1 0 1 1 1 0 Bax inhibitor 1 like Chitin_synth_1 PF01644.17 OQR88524.1 - 6.6e-44 149.8 0.0 1.2e-43 148.9 0.0 1.5 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_2 PF03142.15 OQR88524.1 - 6.5e-26 91.0 4.9 1.6e-20 73.3 0.0 3.2 3 0 0 3 3 3 2 Chitin synthase Glyco_trans_2_3 PF13632.6 OQR88524.1 - 2.1e-12 47.4 0.8 2.1e-12 47.4 0.8 1.9 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Chitin_synth_1N PF08407.11 OQR88524.1 - 1.8e-06 27.8 0.8 5.6e-06 26.2 0.7 1.9 2 0 0 2 2 2 1 Chitin synthase N-terminal Glyco_tranf_2_3 PF13641.6 OQR88524.1 - 0.00026 21.0 0.0 0.0017 18.3 0.0 2.1 2 0 0 2 2 2 1 Glycosyltransferase like family 2 MIT PF04212.18 OQR88524.1 - 0.00054 20.0 0.3 0.0014 18.6 0.3 1.8 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain Pkinase PF00069.25 OQR88525.1 - 2.9e-69 233.4 0.0 4.1e-69 232.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQR88525.1 - 5.1e-32 111.2 0.0 8e-32 110.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PX PF00787.24 OQR88525.1 - 5.4e-13 48.9 0.0 1.5e-12 47.5 0.0 1.8 1 0 0 1 1 1 1 PX domain Kinase-like PF14531.6 OQR88525.1 - 6.3e-07 29.0 0.0 1.2e-06 28.0 0.0 1.5 1 0 0 1 1 1 1 Kinase-like FTA2 PF13095.6 OQR88525.1 - 0.00032 20.4 0.1 1.8 8.1 0.0 3.0 3 0 0 3 3 3 2 Kinetochore Sim4 complex subunit FTA2 Pkinase_C PF00433.24 OQR88525.1 - 0.00033 21.3 0.6 0.001 19.7 0.3 2.1 2 0 0 2 2 2 1 Protein kinase C terminal domain APH PF01636.23 OQR88525.1 - 0.011 15.7 0.0 0.021 14.8 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 OQR88525.1 - 0.14 11.1 0.0 0.22 10.5 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain FH2 PF02181.23 OQR88527.1 - 2.7e-52 178.2 8.9 2.6e-48 165.0 5.3 2.2 2 0 0 2 2 2 2 Formin Homology 2 Domain CCDC53 PF10152.9 OQR88527.1 - 1.6e-08 35.1 0.1 1.6e-08 35.1 0.1 3.6 2 1 0 2 2 2 1 Subunit CCDC53 of WASH complex WH2 PF02205.20 OQR88527.1 - 0.00072 19.3 20.3 3.7 7.5 0.1 7.3 8 0 0 8 8 8 4 WH2 motif Sugar_tr PF00083.24 OQR88532.1 - 1e-39 136.7 22.5 3.7e-38 131.6 22.5 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OQR88532.1 - 3.7e-34 118.2 48.5 4.6e-31 108.0 28.8 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Thioesterase PF00975.20 OQR88532.1 - 0.0034 17.5 0.0 0.0058 16.8 0.0 1.3 1 0 0 1 1 1 1 Thioesterase domain Ank_2 PF12796.7 OQR88534.1 - 1.6e-56 188.8 14.5 1.3e-09 38.5 0.1 9.9 6 3 2 9 9 9 8 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OQR88534.1 - 2.7e-36 119.5 16.1 0.00042 20.5 0.0 15.1 15 0 0 15 15 15 8 Ankyrin repeat Ank_4 PF13637.6 OQR88534.1 - 4.6e-35 119.5 20.6 0.00043 20.8 0.0 10.7 8 2 2 10 10 10 8 Ankyrin repeats (many copies) Ank_5 PF13857.6 OQR88534.1 - 3.6e-30 103.6 9.1 1.1e-05 25.5 0.0 11.3 10 2 2 12 12 12 7 Ankyrin repeats (many copies) Ank PF00023.30 OQR88534.1 - 2e-26 91.2 24.6 5.2e-07 29.8 0.0 12.7 13 0 0 13 13 13 7 Ankyrin repeat AMP-binding PF00501.28 OQR88534.1 - 5.5e-10 38.4 0.0 9e-10 37.7 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme DUF249 PF03158.13 OQR88534.1 - 0.014 15.1 1.2 0.37 10.5 0.0 3.2 3 0 0 3 3 3 0 Multigene family 530 protein Anoctamin PF04547.12 OQR88539.1 - 1.6e-83 281.1 15.4 2e-83 280.8 15.4 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel RVT_3 PF13456.6 OQR88540.1 - 8.4e-26 90.2 0.1 9.6e-26 90.0 0.1 1.0 1 0 0 1 1 1 1 Reverse transcriptase-like RNase_H PF00075.24 OQR88540.1 - 2.7e-12 47.1 0.6 2.4e-11 44.0 0.6 1.9 1 1 0 1 1 1 1 RNase H Glyco_hydro_49N PF17433.2 OQR88540.1 - 0.14 11.7 0.0 0.19 11.4 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 49 N-terminal Ig-like domain Pkinase PF00069.25 OQR88541.1 - 1.9e-78 263.5 0.0 3.6e-78 262.6 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQR88541.1 - 5.9e-36 124.1 0.0 1e-35 123.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Ribonuclease_3 PF00636.26 OQR88541.1 - 8.6e-06 26.3 0.1 0.038 14.6 0.0 2.8 2 0 0 2 2 2 2 Ribonuclease III domain Kdo PF06293.14 OQR88541.1 - 0.0043 16.4 0.1 0.0082 15.5 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 OQR88541.1 - 0.0061 15.9 0.0 0.011 15.1 0.0 1.4 1 0 0 1 1 1 1 Kinase-like R3H PF01424.22 OQR88541.1 - 0.0068 16.4 0.5 0.032 14.2 0.1 2.3 2 0 0 2 2 2 1 R3H domain MARVEL PF01284.23 OQR88541.1 - 0.011 15.8 0.2 0.022 14.8 0.2 1.4 1 0 0 1 1 1 0 Membrane-associating domain YrbL-PhoP_reg PF10707.9 OQR88541.1 - 0.13 11.8 0.0 0.32 10.5 0.0 1.6 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL DUF2243 PF10002.9 OQR88541.1 - 0.14 12.3 1.2 6.3 6.9 0.1 3.1 3 0 0 3 3 3 0 Predicted membrane protein (DUF2243) DUF1456 PF07308.13 OQR88541.1 - 0.17 12.2 0.1 0.73 10.2 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1456) Trm112p PF03966.16 OQR88542.1 - 1.2e-14 54.6 0.1 1.8e-14 54.0 0.1 1.3 1 0 0 1 1 1 1 Trm112p-like protein A2L_zn_ribbon PF08792.10 OQR88542.1 - 0.037 13.7 0.4 0.12 12.1 0.1 1.9 2 0 0 2 2 2 0 A2L zinc ribbon domain ADK_lid PF05191.14 OQR88542.1 - 0.097 12.7 0.1 0.22 11.5 0.1 1.6 1 0 0 1 1 1 0 Adenylate kinase, active site lid GN3L_Grn1 PF08701.11 OQR88543.1 - 4.6e-15 55.5 24.4 4.6e-15 55.5 24.4 2.3 2 0 0 2 2 1 1 GNL3L/Grn1 putative GTPase MMR_HSR1 PF01926.23 OQR88543.1 - 1.2e-14 54.4 0.2 4.5e-12 46.1 0.0 2.7 2 1 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 OQR88543.1 - 1.1e-08 34.7 0.3 7e-06 25.7 0.0 2.4 2 0 0 2 2 2 2 Ferrous iron transport protein B RsgA_GTPase PF03193.16 OQR88543.1 - 1.5e-07 31.5 0.9 0.0052 16.7 0.1 2.7 3 0 0 3 3 3 2 RsgA GTPase AIG1 PF04548.16 OQR88543.1 - 0.0023 17.3 0.0 0.0023 17.3 0.0 1.8 2 0 0 2 2 2 1 AIG1 family SusD-like PF12741.7 OQR88543.1 - 0.0044 16.0 0.0 0.0067 15.4 0.0 1.2 1 0 0 1 1 1 1 Susd and RagB outer membrane lipoprotein Nuc_deoxyri_tr2 PF15891.5 OQR88543.1 - 0.019 15.2 0.0 0.05 13.9 0.0 1.8 1 1 0 1 1 1 0 Nucleoside 2-deoxyribosyltransferase like Roc PF08477.13 OQR88543.1 - 0.032 14.5 0.3 3 8.1 0.0 3.6 4 0 0 4 4 4 0 Ras of Complex, Roc, domain of DAPkinase cobW PF02492.19 OQR88543.1 - 0.049 13.2 1.2 0.078 12.6 0.5 1.7 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_16 PF13191.6 OQR88543.1 - 0.082 13.3 0.1 1.2 9.4 0.0 2.3 2 0 0 2 2 2 0 AAA ATPase domain Dynamin_N PF00350.23 OQR88543.1 - 0.091 12.8 0.3 0.091 12.8 0.3 3.1 2 2 1 3 3 3 0 Dynamin family Cas3_C PF18395.1 OQR88543.1 - 0.097 13.2 0.3 0.4 11.2 0.0 2.2 2 0 0 2 2 2 0 Cas3 C-terminal domain AAA_18 PF13238.6 OQR88543.1 - 0.6 10.7 0.0 0.6 10.7 0.0 2.8 2 1 1 3 3 3 0 AAA domain DUF3040 PF11239.8 OQR88543.1 - 0.9 9.9 4.1 45 4.4 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3040) DUF3915 PF13054.6 OQR88543.1 - 2.6 8.1 4.8 1.1 9.3 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3915) SIKE PF05769.11 OQR88544.1 - 0.0062 16.5 0.1 0.0095 15.9 0.1 1.4 1 0 0 1 1 1 1 SIKE family JIP_LZII PF16471.5 OQR88544.1 - 0.069 13.3 1.7 0.13 12.5 0.4 2.1 2 0 0 2 2 2 0 JNK-interacting protein leucine zipper II VP40 PF07447.12 OQR88544.1 - 0.091 11.9 0.0 0.11 11.5 0.0 1.2 1 0 0 1 1 1 0 Matrix protein VP40 EMP24_GP25L PF01105.24 OQR88544.1 - 0.35 10.8 3.1 0.51 10.3 3.1 1.3 1 1 0 1 1 1 0 emp24/gp25L/p24 family/GOLD Gly-zipper_Omp PF13488.6 OQR88545.1 - 0.018 15.0 9.0 0.027 14.5 9.0 1.2 1 0 0 1 1 1 0 Glycine zipper Choline_transpo PF04515.12 OQR88545.1 - 0.023 13.9 0.1 0.048 12.8 0.0 1.5 2 0 0 2 2 2 0 Plasma-membrane choline transporter Gly-zipper_YMGG PF13441.6 OQR88545.1 - 0.053 13.3 8.9 0.095 12.5 8.9 1.3 1 0 0 1 1 1 0 YMGG-like Gly-zipper Bacteriocin_IIc PF10439.9 OQR88545.1 - 0.26 11.5 3.5 0.38 10.9 3.5 1.2 1 0 0 1 1 1 0 Bacteriocin class II with double-glycine leader peptide Rick_17kDa_Anti PF05433.15 OQR88545.1 - 2.4 8.1 11.1 5 7.1 11.1 1.5 1 1 0 1 1 1 0 Glycine zipper 2TM domain Gly-zipper_OmpA PF13436.6 OQR88545.1 - 3.9 7.3 8.1 9.2 6.1 8.1 1.5 1 1 0 1 1 1 0 Glycine-zipper domain Baculo_PEP_C PF04513.12 OQR88547.1 - 0.24 11.4 6.1 1.5 8.9 0.7 2.9 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF4140 PF13600.6 OQR88547.1 - 1.6 9.2 13.6 2.6 8.6 1.3 4.6 4 1 2 6 6 6 0 N-terminal domain of unknown function (DUF4140) Atg14 PF10186.9 OQR88547.1 - 2.8 7.0 25.6 0.053 12.6 5.8 2.6 3 0 0 3 3 3 0 Vacuolar sorting 38 and autophagy-related subunit 14 DASH_Dam1 PF08653.10 OQR88547.1 - 4.4 7.2 9.8 7.4 6.5 0.3 3.5 3 0 0 3 3 3 0 DASH complex subunit Dam1 BLOC1_2 PF10046.9 OQR88547.1 - 4.7 7.6 19.5 0.14 12.5 4.0 3.5 3 1 1 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF1192 PF06698.11 OQR88547.1 - 9.4 6.4 13.7 10 6.3 0.4 3.9 4 0 0 4 4 4 0 Protein of unknown function (DUF1192) Mnd1 PF03962.15 OQR88548.1 - 1.2e-25 89.5 0.2 2.5e-25 88.5 0.2 1.6 1 0 0 1 1 1 1 Mnd1 HTH domain LZ3wCH PF18517.1 OQR88548.1 - 1.2e-12 47.7 1.8 1.2e-12 47.7 1.8 2.9 3 1 0 3 3 3 1 Leucine zipper with capping helix domain DUF4509 PF14970.6 OQR88548.1 - 0.0012 18.8 1.8 0.0019 18.1 1.8 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4509) DUF1664 PF07889.12 OQR88548.1 - 0.02 14.9 0.9 0.044 13.8 0.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) AMH_N PF04709.12 OQR88548.1 - 0.096 11.6 1.1 0.14 11.0 1.1 1.2 1 0 0 1 1 1 0 Anti-Mullerian hormone, N terminal region ABC_tran_Xtn PF12848.7 OQR88548.1 - 0.097 12.7 5.1 0.22 11.6 5.1 1.6 1 0 0 1 1 1 0 ABC transporter FapA PF03961.13 OQR88548.1 - 0.1 11.2 7.8 0.12 10.9 7.4 1.4 1 1 0 1 1 1 0 Flagellar Assembly Protein A YscO PF07321.12 OQR88548.1 - 0.67 9.9 13.8 0.15 12.0 9.9 1.8 2 0 0 2 2 2 0 Type III secretion protein YscO Atg14 PF10186.9 OQR88548.1 - 1.1 8.3 9.9 1.6 7.8 9.9 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Snapin_Pallidin PF14712.6 OQR88548.1 - 1.9 8.9 9.1 4.3 7.8 7.7 2.2 1 1 1 2 2 2 0 Snapin/Pallidin CCDC-167 PF15188.6 OQR88548.1 - 5.7 7.3 8.8 32 5.0 6.9 2.2 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 DUF1325 PF07039.11 OQR88549.1 - 1.4e-28 99.6 0.0 2.2e-28 99.0 0.0 1.3 1 0 0 1 1 1 1 SGF29 tudor-like domain Tudor_3 PF18115.1 OQR88549.1 - 0.00083 19.1 0.0 0.0016 18.2 0.0 1.5 1 0 0 1 1 1 1 DNA repair protein Crb2 Tudor domain LBR_tudor PF09465.10 OQR88549.1 - 0.017 14.9 0.0 1.2 9.0 0.0 2.3 2 0 0 2 2 2 0 Lamin-B receptor of TUDOR domain Agenet PF05641.12 OQR88549.1 - 0.15 12.5 0.1 2.9 8.4 0.1 2.5 2 0 0 2 2 2 0 Agenet domain p450 PF00067.22 OQR88550.1 - 5.8e-08 31.9 0.0 7.5e-08 31.5 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 CIDE-N PF02017.15 OQR88550.1 - 0.12 12.4 0.1 0.36 10.9 0.0 1.7 2 0 0 2 2 2 0 CIDE-N domain Band_3_cyto PF07565.13 OQR88550.1 - 0.13 12.1 0.0 0.16 11.7 0.0 1.2 1 0 0 1 1 1 0 Band 3 cytoplasmic domain LRR_8 PF13855.6 OQR88552.1 - 1.2e-09 37.8 7.9 3.7e-08 33.0 3.4 3.5 2 1 1 3 3 3 2 Leucine rich repeat LRR_4 PF12799.7 OQR88552.1 - 2.8e-07 30.7 4.4 0.00043 20.6 0.2 3.6 2 1 1 3 3 3 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 OQR88552.1 - 0.019 15.5 6.5 1.4 9.8 0.5 5.0 4 1 0 4 4 4 0 Leucine Rich Repeat DUF3959 PF13105.6 OQR88552.1 - 0.021 14.3 1.8 0.03 13.8 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3959) LRRNT_2 PF08263.12 OQR88552.1 - 0.23 11.8 1.8 0.59 10.5 1.8 1.7 1 0 0 1 1 1 0 Leucine rich repeat N-terminal domain MAPEG PF01124.18 OQR88553.1 - 2e-18 66.6 0.0 2.9e-18 66.0 0.0 1.2 1 0 0 1 1 1 1 MAPEG family SNO PF01174.19 OQR88554.1 - 1.1e-40 139.5 0.0 1.8e-40 138.8 0.0 1.3 1 0 0 1 1 1 1 SNO glutamine amidotransferase family ECH_1 PF00378.20 OQR88554.1 - 1.4e-39 136.0 0.0 2e-39 135.4 0.0 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 OQR88554.1 - 2.4e-20 73.3 0.0 3e-20 73.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase GATase_3 PF07685.14 OQR88554.1 - 2.3e-09 37.1 0.0 4.4e-09 36.2 0.0 1.4 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain Peptidase_S51 PF03575.17 OQR88554.1 - 0.00019 21.2 0.0 0.00031 20.4 0.0 1.3 1 0 0 1 1 1 1 Peptidase family S51 DJ-1_PfpI PF01965.24 OQR88554.1 - 0.0048 16.7 0.0 0.018 14.9 0.0 1.9 2 0 0 2 2 2 1 DJ-1/PfpI family GATase PF00117.28 OQR88554.1 - 0.054 13.3 0.0 0.08 12.7 0.0 1.4 1 0 0 1 1 1 0 Glutamine amidotransferase class-I PolyA_pol_RNAbd PF12627.7 OQR88554.1 - 0.073 12.8 0.1 0.23 11.3 0.0 1.9 2 0 0 2 2 2 0 Probable RNA and SrmB- binding site of polymerase A Ndc1_Nup PF09531.10 OQR88555.1 - 0.74 8.4 6.8 0.96 8.1 6.8 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup BTHB PF18410.1 OQR88556.1 - 1.2e-05 25.0 0.2 2.9e-05 23.8 0.2 1.6 1 0 0 1 1 1 1 Basic tilted helix bundle domain DUF4777 PF16007.5 OQR88556.1 - 0.012 15.8 0.2 0.071 13.4 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4777) BACK PF07707.15 OQR88556.1 - 0.072 13.2 1.5 0.11 12.6 0.2 2.0 2 0 0 2 2 2 0 BTB And C-terminal Kelch WSD PF15613.6 OQR88558.1 - 2.1e-13 50.6 0.2 2.1e-13 50.6 0.2 5.2 3 3 0 3 3 3 1 Williams-Beuren syndrome DDT (WSD), D-TOX E motif PHD PF00628.29 OQR88558.1 - 3.4e-11 42.8 24.6 4.2e-06 26.5 10.5 2.6 2 0 0 2 2 2 2 PHD-finger zf-HC5HC2H PF13771.6 OQR88558.1 - 4.7e-07 30.0 15.4 0.002 18.4 5.5 2.9 2 0 0 2 2 2 2 PHD-like zinc-binding domain zf-PHD-like PF15446.6 OQR88558.1 - 0.00045 19.9 14.9 0.028 14.1 1.0 3.7 2 1 1 3 3 3 2 PHD/FYVE-zinc-finger like domain PHD_2 PF13831.6 OQR88558.1 - 0.35 10.5 14.0 0.46 10.1 0.3 3.0 3 0 0 3 3 3 0 PHD-finger SOBP PF15279.6 OQR88558.1 - 6.4 7.3 8.2 16 6.0 8.2 1.7 1 0 0 1 1 1 0 Sine oculis-binding protein TUDOR_5 PF18359.1 OQR88560.1 - 0.0017 18.0 0.1 0.14 11.8 0.0 3.4 3 0 0 3 3 3 1 Histone methyltransferase Tudor domain 1 TTL PF03133.15 OQR88562.1 - 5e-82 275.4 3.4 5.3e-82 275.3 2.8 1.3 1 1 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 OQR88562.1 - 3.9e-09 36.1 0.2 0.00055 19.3 0.0 2.6 2 0 0 2 2 2 2 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 OQR88562.1 - 1.5e-05 24.4 0.0 0.0075 15.6 0.0 2.2 2 0 0 2 2 2 2 Sugar-transfer associated ATP-grasp RimK PF08443.11 OQR88562.1 - 0.056 13.0 0.0 3.1 7.3 0.0 2.3 2 0 0 2 2 2 0 RimK-like ATP-grasp domain GSH-S_ATP PF02955.16 OQR88562.1 - 0.067 12.6 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 Prokaryotic glutathione synthetase, ATP-grasp domain cNMP_binding PF00027.29 OQR88563.1 - 6.1e-43 144.8 0.1 4.8e-18 65.0 0.0 3.6 3 0 0 3 3 3 3 Cyclic nucleotide-binding domain SURF1 PF02104.15 OQR88564.1 - 2.2e-31 109.4 0.0 2.7e-31 109.2 0.0 1.0 1 0 0 1 1 1 1 SURF1 family DUF3768 PF12599.8 OQR88564.1 - 0.029 14.4 0.0 2.5 8.2 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3768) Elicitin PF00964.17 OQR88566.1 - 0.0034 17.4 0.0 0.008 16.2 0.0 1.6 1 1 0 1 1 1 1 Elicitin Elicitin PF00964.17 OQR88567.1 - 0.00085 19.4 0.1 0.0026 17.8 0.1 1.9 1 0 0 1 1 1 1 Elicitin KAR9 PF08580.10 OQR88567.1 - 1.9 6.9 9.3 2.2 6.7 9.3 1.0 1 0 0 1 1 1 0 Yeast cortical protein KAR9 Peptidase_S21 PF00716.17 OQR88567.1 - 7.6 6.1 19.7 9.9 5.7 19.7 1.3 1 0 0 1 1 1 0 Assemblin (Peptidase family S21) HSP70 PF00012.20 OQR88569.1 - 1.8e-157 525.1 1.7 2e-157 525.0 1.7 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 OQR88569.1 - 1e-12 47.5 0.1 1.4e-12 47.1 0.1 1.1 1 0 0 1 1 1 1 MreB/Mbl protein DDR PF08841.10 OQR88569.1 - 0.0022 17.0 0.1 0.018 14.1 0.1 2.1 2 0 0 2 2 2 1 Diol dehydratase reactivase ATPase-like domain HOIP-UBA PF16678.5 OQR88569.1 - 0.069 13.2 0.0 0.16 12.0 0.0 1.5 1 0 0 1 1 1 0 HOIP UBA domain pair DUF2073 PF09846.9 OQR88569.1 - 0.071 13.0 0.4 2.9 7.8 0.0 2.4 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2073) ABC_membrane PF00664.23 OQR88570.1 - 4.5e-59 200.4 6.8 5.5e-59 200.0 6.8 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 OQR88570.1 - 6.2e-20 72.1 0.0 1.1e-19 71.3 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_29 PF13555.6 OQR88570.1 - 0.00079 19.1 0.1 0.0017 18.1 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain UPF0114 PF03350.16 OQR88570.1 - 0.0051 17.0 1.7 0.0062 16.7 0.1 2.0 2 0 0 2 2 2 1 Uncharacterized protein family, UPF0114 RsgA_GTPase PF03193.16 OQR88570.1 - 0.0055 16.6 0.7 0.0083 16.0 0.0 1.6 2 0 0 2 2 1 1 RsgA GTPase AAA_16 PF13191.6 OQR88570.1 - 0.006 17.0 0.1 0.013 15.9 0.1 1.5 1 0 0 1 1 1 1 AAA ATPase domain DUF87 PF01935.17 OQR88570.1 - 0.011 15.9 0.1 0.019 15.0 0.1 1.3 1 0 0 1 1 1 0 Helicase HerA, central domain AAA_5 PF07728.14 OQR88570.1 - 0.011 15.7 0.0 0.025 14.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) SRP54 PF00448.22 OQR88570.1 - 0.03 13.9 0.1 0.08 12.6 0.0 1.7 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_22 PF13401.6 OQR88570.1 - 0.045 14.0 0.1 0.12 12.6 0.0 1.7 2 0 0 2 2 2 0 AAA domain G-alpha PF00503.20 OQR88570.1 - 0.057 12.6 0.1 0.086 12.0 0.1 1.2 1 0 0 1 1 1 0 G-protein alpha subunit APS_kinase PF01583.20 OQR88570.1 - 0.057 13.3 0.1 0.12 12.2 0.1 1.5 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_30 PF13604.6 OQR88570.1 - 0.061 13.0 0.2 0.19 11.4 0.0 1.9 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 OQR88570.1 - 0.11 11.7 0.0 0.21 10.9 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_33 PF13671.6 OQR88570.1 - 0.17 12.1 0.1 0.44 10.7 0.0 1.6 2 0 0 2 2 2 0 AAA domain adh_short PF00106.25 OQR88572.1 - 5.6e-15 55.3 0.0 8.7e-15 54.7 0.0 1.3 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OQR88572.1 - 2.7e-08 33.7 0.0 4.4e-08 33.0 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Shikimate_DH PF01488.20 OQR88572.1 - 0.0017 18.4 0.0 0.0027 17.8 0.0 1.2 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase KR PF08659.10 OQR88572.1 - 0.022 14.7 0.1 0.038 13.9 0.1 1.4 1 0 0 1 1 1 0 KR domain 2-Hacid_dh_C PF02826.19 OQR88572.1 - 0.029 13.7 0.1 0.043 13.2 0.1 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Epimerase PF01370.21 OQR88572.1 - 0.034 13.6 0.1 0.043 13.3 0.1 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family F420_oxidored PF03807.17 OQR88572.1 - 0.11 13.1 0.0 0.21 12.2 0.0 1.4 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent KIAA1430 PF13879.6 OQR88574.1 - 1.2e-10 42.1 1.6 1.2e-10 42.1 1.6 3.0 2 1 1 3 3 3 1 KIAA1430 homologue Beta-lactamase PF00144.24 OQR88576.1 - 1.1e-38 133.3 0.0 1.7e-38 132.7 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase Sybindin PF04099.12 OQR88577.1 - 1.8e-40 138.2 0.0 2.1e-40 138.0 0.0 1.0 1 0 0 1 1 1 1 Sybindin-like family Sedlin_N PF04628.13 OQR88577.1 - 1.5e-05 25.1 0.0 1.5e-05 25.1 0.0 1.2 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Myosin_head PF00063.21 OQR88578.1 - 6.6e-112 374.9 0.1 1e-111 374.3 0.1 1.3 1 0 0 1 1 1 1 Myosin head (motor domain) Transket_pyr PF02779.24 OQR88578.1 - 3.3e-58 196.3 0.0 5.7e-58 195.5 0.0 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain E1_dh PF00676.20 OQR88578.1 - 1.7e-51 175.0 0.0 4.3e-51 173.7 0.0 1.7 1 0 0 1 1 1 1 Dehydrogenase E1 component DUF4419 PF14388.6 OQR88578.1 - 1.7e-41 142.6 0.0 2.5e-36 125.7 0.0 2.6 1 1 1 2 2 2 2 Domain of unknown function (DUF4419) OxoGdeHyase_C PF16870.5 OQR88578.1 - 2.2e-41 141.1 0.0 4.8e-41 140.0 0.0 1.6 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase C-terminal EF-hand_7 PF13499.6 OQR88578.1 - 3.6e-27 94.6 2.7 3.7e-12 46.5 0.0 4.2 3 0 0 3 3 3 3 EF-hand domain pair EF-hand_1 PF00036.32 OQR88578.1 - 5.4e-26 88.2 10.9 1.3e-05 24.4 0.1 5.7 5 0 0 5 5 5 5 EF hand fn3 PF00041.21 OQR88578.1 - 7.9e-23 80.6 7.3 9.4e-06 25.9 0.0 6.5 6 0 0 6 6 6 4 Fibronectin type III domain EF-hand_5 PF13202.6 OQR88578.1 - 7.8e-22 75.7 10.5 0.00032 20.0 0.2 5.6 5 0 0 5 5 5 5 EF hand EF-hand_6 PF13405.6 OQR88578.1 - 9.2e-20 68.8 9.2 0.0042 16.9 0.2 5.8 5 0 0 5 5 5 5 EF-hand domain EF-hand_8 PF13833.6 OQR88578.1 - 2.7e-16 59.2 10.3 0.0051 16.6 0.2 5.7 4 1 1 5 5 5 5 EF-hand domain pair PH PF00169.29 OQR88578.1 - 1.7e-12 47.7 0.0 6e-12 46.0 0.0 2.0 1 0 0 1 1 1 1 PH domain Pur_ac_phosph_N PF16656.5 OQR88578.1 - 2.3e-11 44.1 3.6 0.091 13.3 0.0 5.6 5 0 0 5 5 5 3 Purple acid Phosphatase, N-terminal domain DUF2369 PF10179.9 OQR88578.1 - 0.00032 21.0 0.0 37 4.8 0.0 4.7 4 0 0 4 4 4 0 Uncharacterised conserved protein (DUF2369) PH_11 PF15413.6 OQR88578.1 - 0.0048 17.3 0.1 0.072 13.5 0.0 2.7 2 0 0 2 2 2 1 Pleckstrin homology domain LXG PF04740.12 OQR88578.1 - 0.006 16.3 0.3 0.015 15.0 0.3 1.6 1 0 0 1 1 1 1 LXG domain of WXG superfamily SPARC_Ca_bdg PF10591.9 OQR88578.1 - 0.0064 16.8 0.5 0.14 12.5 0.0 3.0 3 0 0 3 3 2 1 Secreted protein acidic and rich in cysteine Ca binding region RNA_helicase PF00910.22 OQR88578.1 - 0.054 13.9 0.2 0.28 11.6 0.0 2.4 2 0 0 2 2 1 0 RNA helicase AAA_19 PF13245.6 OQR88578.1 - 0.082 13.2 0.0 0.23 11.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain STI1 PF17830.1 OQR88578.1 - 0.086 12.8 2.9 53 3.8 0.3 4.5 4 0 0 4 4 4 0 STI1 domain NACHT PF05729.12 OQR88578.1 - 0.11 12.4 0.0 0.31 10.9 0.0 1.8 1 0 0 1 1 1 0 NACHT domain Peptidase_M13_N PF05649.13 OQR88579.1 - 4.1e-74 250.6 0.5 5.4e-74 250.2 0.5 1.2 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13 PF01431.21 OQR88579.1 - 2.4e-66 223.3 0.0 4.3e-66 222.4 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M13 CENP-P PF13096.6 OQR88579.1 - 0.02 14.6 0.1 0.12 12.1 0.0 2.1 2 0 0 2 2 2 0 CENP-A-nucleosome distal (CAD) centromere subunit, CENP-P Fibrinogen_C PF00147.18 OQR88579.1 - 0.055 13.3 0.0 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 Fibrinogen beta and gamma chains, C-terminal globular domain ABC_membrane PF00664.23 OQR88580.1 - 1.8e-25 90.1 25.2 2.4e-25 89.7 25.2 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region Rsa3 PF14615.6 OQR88580.1 - 0.081 12.5 0.0 0.35 10.5 0.0 2.1 2 0 0 2 2 2 0 Ribosome-assembly protein 3 KASH_CCD PF14662.6 OQR88582.1 - 0.0019 18.1 26.3 0.0019 18.1 26.3 4.6 2 2 3 5 5 5 1 Coiled-coil region of CCDC155 or KASH CALCOCO1 PF07888.11 OQR88582.1 - 0.0025 16.7 32.2 0.0025 16.7 32.2 2.7 1 1 2 3 3 3 1 Calcium binding and coiled-coil domain (CALCOCO1) like TolA_bind_tri PF16331.5 OQR88582.1 - 0.018 15.1 4.9 0.018 15.1 4.9 6.6 3 1 2 6 6 6 0 TolA binding protein trimerisation DegS PF05384.11 OQR88582.1 - 3.3 7.2 40.5 0.014 14.9 17.0 3.8 2 1 1 3 3 3 0 Sensor protein DegS ADIP PF11559.8 OQR88582.1 - 3.9 7.6 67.6 1.7 8.7 4.6 6.0 1 1 4 5 5 5 0 Afadin- and alpha -actinin-Binding T2SSG PF08334.11 OQR88582.1 - 4.5 7.4 6.2 7.4 6.7 0.0 3.2 1 1 1 3 3 3 0 Type II secretion system (T2SS), protein G DUF4618 PF15397.6 OQR88582.1 - 5.5 6.3 46.7 12 5.2 0.1 4.6 2 1 1 3 3 3 0 Domain of unknown function (DUF4618) Spc7 PF08317.11 OQR88582.1 - 5.5 5.8 61.8 0.2 10.5 7.4 4.3 1 1 3 4 4 4 0 Spc7 kinetochore protein Ank_2 PF12796.7 OQR88584.1 - 4.1e-24 85.0 13.6 7.2e-07 29.7 0.4 7.4 1 1 7 8 8 8 8 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OQR88584.1 - 3.9e-19 68.5 21.2 0.43 11.0 0.1 12.8 5 4 9 14 14 14 7 Ankyrin repeats (many copies) Ank_4 PF13637.6 OQR88584.1 - 4.1e-19 68.7 10.2 0.0013 19.3 0.1 8.8 7 3 3 10 10 10 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQR88584.1 - 1.2e-12 46.8 14.2 3.7 8.4 0.1 12.0 11 3 2 13 13 13 3 Ankyrin repeat Ank PF00023.30 OQR88584.1 - 3.7e-05 24.0 6.3 26 5.5 0.2 8.0 6 3 2 8 8 8 1 Ankyrin repeat DUF3447 PF11929.8 OQR88584.1 - 0.71 9.9 12.3 3.3 7.7 2.7 4.9 4 1 2 6 6 6 0 Domain of unknown function (DUF3447) Steroid_dh PF02544.16 OQR88585.1 - 2.6e-31 108.6 1.6 3.9e-31 108.1 1.6 1.3 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1295 PF06966.12 OQR88585.1 - 0.0058 16.2 0.2 0.0086 15.6 0.2 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF1295) ubiquitin PF00240.23 OQR88585.1 - 0.0061 16.3 0.2 0.029 14.1 0.2 1.9 1 1 0 1 1 1 1 Ubiquitin family Ank_4 PF13637.6 OQR88586.1 - 2.6e-20 72.5 1.6 4.5e-05 23.9 0.1 5.7 4 2 2 6 6 6 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 OQR88586.1 - 2.3e-19 69.7 6.0 5.4e-08 33.3 0.1 4.1 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OQR88586.1 - 2.4e-17 62.8 2.7 0.037 14.4 0.1 6.9 1 1 6 7 7 7 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQR88586.1 - 1.6e-11 43.4 2.8 0.51 11.1 0.0 7.3 4 3 4 8 8 8 2 Ankyrin repeat DUF5049 PF16468.5 OQR88586.1 - 1.4e-06 28.1 0.6 3.5 7.6 0.0 5.6 4 2 2 6 6 6 1 Domain of unknown function (DUF5049) Ank PF00023.30 OQR88586.1 - 0.00023 21.4 1.1 47 4.7 0.0 5.8 3 3 2 5 5 5 0 Ankyrin repeat VHL_C PF17211.3 OQR88586.1 - 0.026 14.5 0.1 22 5.2 0.0 4.3 5 1 0 5 5 5 0 VHL box domain BTHB PF18410.1 OQR88586.1 - 0.08 12.8 0.2 85 3.1 0.0 4.8 6 1 1 7 7 7 0 Basic tilted helix bundle domain IL8 PF00048.20 OQR88586.1 - 0.11 12.7 0.0 7.7 6.7 0.0 2.7 2 0 0 2 2 2 0 Small cytokines (intecrine/chemokine), interleukin-8 like Helicase_PWI PF18149.1 OQR88586.1 - 0.11 12.7 0.8 47 4.2 0.0 3.6 3 1 0 3 3 3 0 N-terminal helicase PWI domain Sec7_N PF12783.7 OQR88589.1 - 0.08 12.8 0.0 0.17 11.8 0.0 1.5 1 0 0 1 1 1 0 Guanine nucleotide exchange factor in Golgi transport N-terminal FRG1 PF06229.12 OQR88590.1 - 0.00038 20.2 0.0 0.38 10.5 0.0 2.2 1 1 1 2 2 2 2 FRG1-like domain Rubredoxin_2 PF18073.1 OQR88590.1 - 0.013 15.2 12.1 0.035 13.8 0.3 3.9 4 0 0 4 4 4 0 Rubredoxin metal binding domain RicinB_lectin_2 PF14200.6 OQR88590.1 - 0.015 16.0 2.0 0.015 16.0 2.0 2.6 1 1 2 3 3 3 0 Ricin-type beta-trefoil lectin domain-like DUF3624 PF12292.8 OQR88590.1 - 0.017 15.5 0.4 8.9 6.8 0.0 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3624) DUF3716 PF12511.8 OQR88590.1 - 0.28 11.2 5.9 1.1 9.4 1.0 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF3716) CDH-cyt PF16010.5 OQR88590.1 - 2 8.0 8.5 8.8 6.0 0.2 2.9 1 1 2 3 3 3 0 Cytochrome domain of cellobiose dehydrogenase TetR_C_8 PF14278.6 OQR88593.1 - 0.073 13.2 0.1 0.35 11.0 0.0 2.1 2 0 0 2 2 2 0 Transcriptional regulator C-terminal region T2SSM PF04612.12 OQR88593.1 - 0.72 9.9 10.0 1.2 9.2 10.0 1.2 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein M YlqD PF11068.8 OQR88593.1 - 2.1 8.7 13.4 4.1 7.8 13.4 1.4 1 0 0 1 1 1 0 YlqD protein START PF01852.19 OQR88594.1 - 5.8e-06 25.9 0.1 9.8e-06 25.1 0.1 1.3 1 0 0 1 1 1 1 START domain C1_1 PF00130.22 OQR88594.1 - 0.029 14.2 3.0 0.071 13.0 3.0 1.6 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) FYVE_2 PF02318.16 OQR88594.1 - 0.098 12.9 1.6 0.2 11.9 1.6 1.4 1 0 0 1 1 1 0 FYVE-type zinc finger FYVE PF01363.21 OQR88594.1 - 0.11 12.6 4.9 0.24 11.6 4.9 1.5 1 0 0 1 1 1 0 FYVE zinc finger zf-RING_10 PF16685.5 OQR88594.1 - 0.33 11.1 4.4 0.79 9.9 4.4 1.6 1 0 0 1 1 1 0 zinc RING finger of MSL2 PHD PF00628.29 OQR88594.1 - 0.5 10.3 4.7 1.2 9.1 4.7 1.7 1 0 0 1 1 1 0 PHD-finger DUF501 PF04417.12 OQR88596.1 - 0.01 15.7 0.2 0.012 15.4 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF501) GST_C_3 PF14497.6 OQR88597.1 - 1.4e-15 57.3 0.0 2e-15 56.8 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 OQR88597.1 - 4.2e-09 36.6 0.0 1.3e-08 35.0 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 OQR88597.1 - 3.6e-06 27.1 0.0 6.2e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 OQR88597.1 - 5.7e-06 26.3 0.0 2.5e-05 24.2 0.0 2.0 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 OQR88597.1 - 0.0032 17.9 0.0 0.0071 16.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Ank_4 PF13637.6 OQR88599.1 - 8.6e-28 96.4 6.9 3.3e-16 59.4 0.3 3.4 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 OQR88599.1 - 9.3e-26 89.6 6.0 4.3e-10 39.7 0.1 3.3 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 OQR88599.1 - 2.9e-25 88.7 0.5 6.2e-20 71.6 0.4 2.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OQR88599.1 - 1.2e-20 71.3 0.7 1.6e-07 31.1 0.0 4.1 4 0 0 4 4 4 3 Ankyrin repeat Ank PF00023.30 OQR88599.1 - 3.5e-18 65.2 1.7 2.9e-06 27.5 0.1 4.0 4 0 0 4 4 4 3 Ankyrin repeat F-box-like PF12937.7 OQR88599.1 - 1.3e-07 31.4 0.5 2.5e-07 30.5 0.5 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 OQR88599.1 - 0.00075 19.3 0.1 0.0014 18.4 0.1 1.4 1 0 0 1 1 1 1 F-box domain RNA_ligase PF09414.10 OQR88602.1 - 1.5e-27 96.9 0.0 2.6e-27 96.1 0.0 1.4 1 0 0 1 1 1 1 RNA ligase HAD_SAK_1 PF10307.9 OQR88602.1 - 1.1e-06 28.6 0.0 2.6e-06 27.4 0.0 1.5 1 0 0 1 1 1 1 HAD domain family 1 in Swiss Army Knife RNA repair proteins NTP_transf_2 PF01909.23 OQR88602.1 - 0.03 14.6 0.0 0.12 12.7 0.0 2.0 1 1 0 1 1 1 0 Nucleotidyltransferase domain SpoU_methylase PF00588.19 OQR88604.1 - 2.8e-26 92.4 0.0 1.8e-24 86.5 0.0 2.7 2 0 0 2 2 2 2 SpoU rRNA Methylase family Castor_Poll_mid PF06241.12 OQR88605.1 - 5.8e-54 180.4 0.0 4.1e-25 87.8 0.0 4.5 5 0 0 5 5 5 2 Castor and Pollux, part of voltage-gated ion channel TrkA_C PF02080.21 OQR88605.1 - 1.3e-05 25.0 0.3 0.28 11.0 0.0 4.5 4 0 0 4 4 4 2 TrkA-C domain OSTbeta PF15048.6 OQR88605.1 - 0.25 11.5 2.5 1.5 9.0 0.1 2.8 3 0 0 3 3 3 0 Organic solute transporter subunit beta protein FAM76 PF16046.5 OQR88606.1 - 0.0012 18.3 3.8 0.0012 18.3 3.8 4.7 3 1 1 4 4 4 1 FAM76 protein LAGLIDADG_WhiA PF14527.6 OQR88606.1 - 0.59 10.2 4.4 2.1 8.5 0.5 3.5 2 0 0 2 2 2 0 WhiA LAGLIDADG-like domain Ank_5 PF13857.6 OQR88607.1 - 0.011 16.0 0.0 1.8 9.0 0.0 2.2 2 0 0 2 2 2 0 Ankyrin repeats (many copies) Ank_4 PF13637.6 OQR88607.1 - 0.037 14.6 0.0 0.17 12.5 0.0 2.0 1 1 0 1 1 1 0 Ankyrin repeats (many copies) Ank_2 PF12796.7 OQR88607.1 - 0.044 14.4 0.0 0.081 13.5 0.0 1.5 1 1 0 1 1 1 0 Ankyrin repeats (3 copies) ABC_membrane PF00664.23 OQR88609.1 - 1.1e-95 320.4 28.3 6.8e-51 173.5 5.4 2.3 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 OQR88609.1 - 8.5e-55 185.0 0.1 5.1e-35 121.0 0.0 2.7 2 0 0 2 2 2 2 ABC transporter AAA_29 PF13555.6 OQR88609.1 - 6.5e-08 32.2 1.0 0.0092 15.7 0.1 2.9 2 0 0 2 2 2 2 P-loop containing region of AAA domain Zeta_toxin PF06414.12 OQR88609.1 - 2.4e-07 30.2 0.1 0.015 14.6 0.0 2.3 2 0 0 2 2 2 2 Zeta toxin AAA_16 PF13191.6 OQR88609.1 - 3e-07 31.0 0.5 0.0034 17.8 0.2 2.5 2 0 0 2 2 2 2 AAA ATPase domain SMC_N PF02463.19 OQR88609.1 - 9.2e-07 28.5 0.9 0.001 18.6 0.0 3.3 2 1 1 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_30 PF13604.6 OQR88609.1 - 9.3e-07 28.7 0.3 0.056 13.2 0.0 3.9 3 1 0 3 3 3 2 AAA domain G-alpha PF00503.20 OQR88609.1 - 2.2e-06 27.1 0.0 0.022 13.9 0.0 2.5 2 0 0 2 2 2 2 G-protein alpha subunit DUF87 PF01935.17 OQR88609.1 - 2.3e-06 27.9 0.1 0.034 14.2 0.0 2.6 2 0 0 2 2 2 2 Helicase HerA, central domain RsgA_GTPase PF03193.16 OQR88609.1 - 1.9e-05 24.6 0.0 0.11 12.4 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_22 PF13401.6 OQR88609.1 - 2.8e-05 24.4 0.1 0.17 12.1 0.0 3.0 2 1 0 2 2 2 2 AAA domain AAA_24 PF13479.6 OQR88609.1 - 0.00038 20.3 0.1 0.37 10.5 0.1 2.8 2 1 0 2 2 2 2 AAA domain AAA_25 PF13481.6 OQR88609.1 - 0.0011 18.5 0.5 0.46 10.0 0.0 3.2 3 0 0 3 3 3 1 AAA domain AAA_15 PF13175.6 OQR88609.1 - 0.0012 18.7 0.0 0.62 9.7 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain AAA_7 PF12775.7 OQR88609.1 - 0.0015 18.1 0.0 2.4 7.6 0.0 2.6 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_21 PF13304.6 OQR88609.1 - 0.0019 18.0 0.3 3.1 7.5 0.1 3.2 3 0 0 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system APS_kinase PF01583.20 OQR88609.1 - 0.0031 17.4 0.1 1 9.2 0.0 2.5 2 0 0 2 2 2 1 Adenylylsulphate kinase Ploopntkinase3 PF18751.1 OQR88609.1 - 0.006 16.5 0.1 0.81 9.6 0.0 2.5 2 0 0 2 2 2 1 P-loop Nucleotide Kinase3 AAA_18 PF13238.6 OQR88609.1 - 0.011 16.3 0.0 4.4 7.9 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 OQR88609.1 - 0.011 16.0 0.2 5.3 7.3 0.1 2.4 2 0 0 2 2 2 0 AAA domain SRP54 PF00448.22 OQR88609.1 - 0.016 14.8 0.0 2.8 7.5 0.0 2.8 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain MMR_HSR1 PF01926.23 OQR88609.1 - 0.019 15.1 0.0 4.6 7.3 0.0 2.7 2 0 0 2 2 2 0 50S ribosome-binding GTPase DLIC PF05783.11 OQR88609.1 - 0.023 13.5 0.1 5.7 5.7 0.0 2.3 2 0 0 2 2 2 0 Dynein light intermediate chain (DLIC) AAA_23 PF13476.6 OQR88609.1 - 0.024 15.1 0.4 6.3 7.2 0.1 2.5 2 0 0 2 2 2 0 AAA domain ATP-synt_ab PF00006.25 OQR88609.1 - 0.028 14.1 0.9 5.4 6.6 0.1 2.5 2 1 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_17 PF13207.6 OQR88609.1 - 0.028 14.8 0.0 9.2 6.7 0.0 2.8 2 0 0 2 2 2 0 AAA domain PRK PF00485.18 OQR88609.1 - 0.042 13.6 0.1 9 6.0 0.0 2.6 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family AAA_33 PF13671.6 OQR88609.1 - 0.047 13.9 0.0 8.2 6.6 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.14 OQR88609.1 - 0.056 13.4 0.0 2.8 7.9 0.0 2.7 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Roc PF08477.13 OQR88609.1 - 0.064 13.5 0.1 4 7.7 0.0 2.8 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase FtsK_SpoIIIE PF01580.18 OQR88609.1 - 0.11 11.8 0.2 16 4.8 0.0 2.5 2 0 0 2 2 2 0 FtsK/SpoIIIE family Pox_A32 PF04665.12 OQR88609.1 - 0.16 11.4 3.0 8.2 5.8 0.1 3.1 4 0 0 4 4 3 0 Poxvirus A32 protein NACHT PF05729.12 OQR88609.1 - 0.22 11.4 1.0 17 5.3 0.1 2.7 3 0 0 3 3 2 0 NACHT domain YwiC PF14256.6 OQR88609.1 - 1.3 9.4 10.4 6.4 7.1 1.0 3.7 3 0 0 3 3 3 0 YwiC-like protein bZIP_2 PF07716.15 OQR88610.1 - 0.046 13.8 0.3 0.046 13.8 0.3 2.2 2 1 0 2 2 2 0 Basic region leucine zipper MFS_1 PF07690.16 OQR88612.1 - 1.6e-25 89.8 43.1 7.8e-21 74.4 11.0 2.9 2 1 1 3 3 3 3 Major Facilitator Superfamily Sugar_tr PF00083.24 OQR88612.1 - 3.2e-13 49.4 18.7 1.5e-12 47.2 3.9 2.3 2 0 0 2 2 2 2 Sugar (and other) transporter OATP PF03137.20 OQR88612.1 - 1.3e-11 43.5 10.6 5.7e-07 28.2 0.0 3.5 2 2 1 3 3 3 3 Organic Anion Transporter Polypeptide (OATP) family Cellsynth_D PF03500.13 OQR88612.1 - 0.13 12.1 0.0 0.28 11.1 0.0 1.4 1 0 0 1 1 1 0 Cellulose synthase subunit D APH PF01636.23 OQR88614.1 - 2.3e-05 24.4 0.2 3.6e-05 23.8 0.2 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 OQR88614.1 - 0.00032 20.4 0.1 0.00045 19.9 0.1 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.22 OQR88614.1 - 0.001 18.7 0.3 0.0027 17.4 0.0 1.8 2 0 0 2 2 2 1 RIO1 family Pkinase PF00069.25 OQR88614.1 - 0.0037 16.7 0.0 0.0054 16.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain EcKinase PF02958.20 OQR88614.1 - 0.013 14.9 0.3 0.032 13.5 0.2 1.6 1 1 0 1 1 1 0 Ecdysteroid kinase DUF1679 PF07914.11 OQR88614.1 - 0.026 13.4 1.0 0.27 10.0 0.2 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF1679) Kdo PF06293.14 OQR88614.1 - 0.096 12.0 0.0 0.18 11.2 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family CMAS PF02353.20 OQR88615.1 - 3.2e-24 85.7 0.1 4.6e-24 85.2 0.1 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Pkinase_Tyr PF07714.17 OQR88616.1 - 1.8e-36 125.8 0.0 2e-36 125.6 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OQR88616.1 - 3.1e-34 118.5 0.0 3.7e-34 118.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 OQR88616.1 - 0.038 12.8 0.0 0.047 12.5 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase WD40 PF00400.32 OQR88617.1 - 3.6e-10 40.2 12.7 0.017 16.0 0.0 5.1 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OQR88617.1 - 5.2e-05 23.5 0.0 7.5 6.9 0.0 3.8 2 1 1 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain BBS2_Mid PF14783.6 OQR88617.1 - 0.13 12.3 0.0 7.6 6.6 0.0 2.7 2 0 0 2 2 2 0 Ciliary BBSome complex subunit 2, middle region eIF2A PF08662.11 OQR88617.1 - 0.14 12.0 0.0 0.81 9.5 0.0 2.1 2 0 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A PAN_4 PF14295.6 OQR88619.1 - 4.3e-08 33.0 4.3 2e-07 30.8 4.3 2.3 1 1 0 1 1 1 1 PAN domain Lactamase_B PF00753.27 OQR88620.1 - 2e-21 76.9 0.1 6.9e-21 75.2 0.1 1.8 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily BLACT_WH PF17778.1 OQR88620.1 - 3.1e-08 33.5 0.1 5.8e-08 32.6 0.1 1.4 1 0 0 1 1 1 1 Beta-lactamase associated winged helix domain Lactamase_B_2 PF12706.7 OQR88620.1 - 5.9e-07 29.2 0.0 9.4e-07 28.5 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_6 PF16661.5 OQR88620.1 - 0.00012 21.6 0.0 0.0002 20.9 0.0 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily domain SNF2_N PF00176.23 OQR88621.1 - 8.5e-36 123.4 0.2 9.7e-35 119.9 0.0 2.4 2 1 0 2 2 2 1 SNF2 family N-terminal domain ResIII PF04851.15 OQR88621.1 - 5e-09 36.4 0.0 6.9e-09 35.9 0.0 1.2 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 OQR88621.1 - 4.5e-05 23.3 0.0 0.0001 22.1 0.0 1.5 1 1 0 1 1 1 1 DEAD/DEAH box helicase DUF2075 PF09848.9 OQR88621.1 - 0.026 13.8 0.0 0.032 13.5 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) DUF1780 PF08682.10 OQR88621.1 - 0.032 13.9 0.0 0.057 13.1 0.0 1.3 1 0 0 1 1 1 0 Putative endonuclease, protein of unknown function (DUF1780) SWI2_SNF2 PF18766.1 OQR88621.1 - 0.1 12.2 0.0 0.17 11.5 0.0 1.3 1 0 0 1 1 1 0 SWI2/SNF2 ATPase DDE_Tnp_4 PF13359.6 OQR88624.1 - 2.7e-10 40.1 0.0 3.9e-10 39.6 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_4 PF13359.6 OQR88625.1 - 6.1e-11 42.2 0.0 8.1e-11 41.8 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_1 PF01609.21 OQR88625.1 - 0.019 14.6 0.1 0.03 13.9 0.1 1.4 1 1 0 1 1 1 0 Transposase DDE domain Lustrin_cystein PF14625.6 OQR88627.1 - 0.013 15.9 1.1 0.022 15.1 0.4 1.7 2 0 0 2 2 2 0 Lustrin, cysteine-rich repeated domain SAS4 PF15460.6 OQR88627.1 - 4.8 7.3 17.2 4.1 7.6 4.8 3.7 3 0 0 3 3 3 0 Something about silencing, SAS, complex subunit 4 GCN5L1 PF06320.13 OQR88629.1 - 9.1e-12 45.1 3.0 1.1e-11 44.9 3.0 1.1 1 0 0 1 1 1 1 GCN5-like protein 1 (GCN5L1) SprA-related PF12118.8 OQR88629.1 - 0.11 11.7 3.0 0.13 11.4 3.0 1.0 1 0 0 1 1 1 0 SprA-related family PDZ_6 PF17820.1 OQR88630.1 - 7.3e-09 35.3 0.0 2e-08 33.9 0.0 1.8 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 OQR88630.1 - 2.6e-08 34.1 0.0 6.1e-08 32.9 0.0 1.7 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 OQR88630.1 - 2.9e-07 30.7 0.0 9.7e-07 29.0 0.0 1.9 1 0 0 1 1 1 1 PDZ domain FAM184 PF15665.5 OQR88630.1 - 0.095 12.5 18.1 0.16 11.8 18.1 1.2 1 0 0 1 1 1 0 Family with sequence similarity 184, A and B FERM_F2 PF18377.1 OQR88632.1 - 0.023 14.6 0.4 0.049 13.6 0.4 1.5 1 0 0 1 1 1 0 FERM F2 acyl-CoA binding protein-like domain Pertussis_S2S3 PF02918.15 OQR88632.1 - 0.062 13.2 0.0 0.1 12.5 0.0 1.3 1 0 0 1 1 1 0 Pertussis toxin, subunit 2 and 3, C-terminal domain HWE_HK PF07536.14 OQR88632.1 - 0.12 13.1 1.0 0.23 12.2 0.1 1.9 2 0 0 2 2 2 0 HWE histidine kinase TPT PF03151.16 OQR88633.1 - 8.6e-50 169.7 29.7 1e-49 169.5 29.7 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 OQR88633.1 - 2e-06 28.0 32.8 0.00053 20.2 13.0 2.1 2 0 0 2 2 2 2 EamA-like transporter family DUF2953 PF11167.8 OQR88633.1 - 0.019 15.0 0.6 4.1 7.5 0.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2953) Bromo_coat PF01318.18 OQR88633.1 - 0.019 15.0 0.0 0.032 14.3 0.0 1.4 1 0 0 1 1 1 0 Bromovirus coat protein UAA PF08449.11 OQR88633.1 - 0.044 13.0 27.8 0.085 12.0 27.8 1.5 1 1 0 1 1 1 0 UAA transporter family Pkinase_Tyr PF07714.17 OQR88636.1 - 9.8e-79 264.3 0.0 4.1e-39 134.4 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 OQR88636.1 - 5.7e-63 212.7 0.0 1.8e-30 106.2 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Haspin_kinase PF12330.8 OQR88636.1 - 0.17 10.8 0.0 1.4 7.8 0.0 2.1 2 0 0 2 2 2 0 Haspin like kinase domain CBFD_NFYB_HMF PF00808.23 OQR88637.1 - 4e-22 78.3 1.0 7.5e-22 77.4 1.0 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CRAL_TRIO PF00650.20 OQR88637.1 - 1.3e-17 64.0 0.1 1.3e-17 64.0 0.1 1.8 2 0 0 2 2 2 1 CRAL/TRIO domain Histone PF00125.24 OQR88637.1 - 3.4e-16 59.8 4.0 6.9e-16 58.8 4.0 1.5 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 COPI_assoc PF08507.10 OQR88637.1 - 0.00013 22.0 6.2 0.00013 22.0 6.2 3.4 3 1 0 3 3 3 1 COPI associated protein CRAL_TRIO_2 PF13716.6 OQR88637.1 - 0.0076 16.4 0.1 0.014 15.6 0.1 1.4 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain NOC3p PF07540.11 OQR88639.1 - 6e-21 74.7 0.1 6e-21 74.7 0.1 2.7 3 0 0 3 3 3 1 Nucleolar complex-associated protein Pkinase_Tyr PF07714.17 OQR88639.1 - 1.8e-18 66.8 2.0 1.3e-10 41.0 0.0 2.7 2 1 1 3 3 3 2 Protein tyrosine kinase Pkinase PF00069.25 OQR88639.1 - 5.4e-11 42.3 0.0 2.4e-08 33.7 0.0 3.1 2 1 1 3 3 3 2 Protein kinase domain Ribosomal_S27e PF01667.17 OQR88639.1 - 0.078 12.7 0.1 1.9 8.3 0.0 2.4 2 0 0 2 2 2 0 Ribosomal protein S27 CBF PF03914.17 OQR88639.1 - 0.69 9.9 0.0 0.69 9.9 0.0 3.0 4 0 0 4 4 4 0 CBF/Mak21 family HAT_KAT11 PF08214.11 OQR88642.1 - 1.8e-26 93.2 4.9 1.8e-26 93.2 4.9 3.4 3 1 0 3 3 3 1 Histone acetylation protein zf-TAZ PF02135.16 OQR88642.1 - 1.7e-21 76.4 55.8 5.6e-13 49.2 12.8 5.0 4 0 0 4 4 4 2 TAZ zinc finger Bromodomain PF00439.25 OQR88642.1 - 2.1e-19 69.4 1.9 3.8e-18 65.3 0.1 3.3 3 0 0 3 3 3 1 Bromodomain ZZ PF00569.17 OQR88642.1 - 5.8e-12 45.2 8.4 5.8e-12 45.2 8.4 4.4 5 0 0 5 5 5 1 Zinc finger, ZZ type KIX_2 PF16987.5 OQR88642.1 - 6.1e-08 32.6 0.2 3.1e-07 30.3 0.2 2.3 1 0 0 1 1 1 1 KIX domain PHD PF00628.29 OQR88642.1 - 7.6e-05 22.5 6.0 7.6e-05 22.5 6.0 5.7 7 1 0 7 7 7 1 PHD-finger KIX PF02172.16 OQR88642.1 - 0.014 15.7 0.0 0.06 13.6 0.0 2.2 1 0 0 1 1 1 0 KIX domain CSN5_C PF18323.1 OQR88642.1 - 0.61 11.0 5.2 4 8.4 0.2 3.6 2 0 0 2 2 2 0 Cop9 signalosome subunit 5 C-terminal domain DUF4407 PF14362.6 OQR88642.1 - 3.8 6.8 8.4 3.6 6.9 5.9 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) TINF2_N PF14973.6 OQR88642.1 - 4.1 7.7 11.5 7.4 6.9 2.1 4.1 3 0 0 3 3 3 0 TERF1-interacting nuclear factor 2 N-terminus MFS_1 PF07690.16 OQR88643.1 - 9.3e-18 64.3 39.0 1.1e-14 54.1 26.0 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily DDE_1 PF03184.19 OQR88645.1 - 4.1e-10 39.6 0.0 9e-09 35.2 0.0 2.2 2 1 0 2 2 2 2 DDE superfamily endonuclease CS PF04969.16 OQR88647.1 - 0.089 13.8 0.0 0.17 12.9 0.0 1.6 1 1 0 1 1 1 0 CS domain TPR_12 PF13424.6 OQR88648.1 - 8.8e-09 35.5 7.6 0.0054 17.0 0.2 3.8 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_1 PF00515.28 OQR88648.1 - 6.9e-08 32.0 6.8 0.017 14.9 0.4 4.5 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.17 OQR88648.1 - 3.2e-05 23.7 5.0 0.032 14.3 0.3 4.6 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_17 PF13431.6 OQR88648.1 - 0.0014 18.8 0.8 10 6.8 0.0 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat GATase_5 PF13507.6 OQR88648.1 - 0.0017 17.5 0.0 0.0033 16.6 0.0 1.4 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain TPR_8 PF13181.6 OQR88648.1 - 0.0053 16.9 1.5 1.1 9.7 0.5 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 OQR88648.1 - 0.019 15.8 0.6 60 4.8 0.0 4.9 5 1 1 6 6 6 0 Tetratricopeptide repeat TPR_10 PF13374.6 OQR88648.1 - 0.021 14.7 0.5 20 5.2 0.0 3.9 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_MalT PF17874.1 OQR88648.1 - 0.029 13.7 5.1 0.23 10.8 0.1 2.4 2 1 1 3 3 3 0 MalT-like TPR region DUF1841 PF08897.11 OQR88648.1 - 0.14 12.2 0.5 0.94 9.5 0.0 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF1841) ANAPC3 PF12895.7 OQR88648.1 - 0.36 11.1 8.1 12 6.2 0.1 3.5 2 1 1 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 Adap_comp_sub PF00928.21 OQR88649.1 - 2e-133 443.7 1.7 1.5e-68 231.0 0.2 2.1 2 0 0 2 2 2 2 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 OQR88649.1 - 1.2e-15 57.7 2.0 6.3e-07 29.4 0.2 2.4 2 0 0 2 2 2 2 Clathrin adaptor complex small chain DUF4231 PF14015.6 OQR88650.1 - 0.18 12.3 2.8 0.6 10.6 2.8 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF4231) DUF3975 PF13126.6 OQR88650.1 - 8.9 6.8 10.2 4 8.0 1.3 3.2 2 1 0 3 3 3 0 Protein of unknown function (DUF3975) Myosin_head PF00063.21 OQR88651.1 - 3.9e-224 745.8 2.0 4.8e-224 745.5 2.0 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) Ank_2 PF12796.7 OQR88651.1 - 2.3e-35 121.0 10.3 1.5e-10 41.5 0.8 5.1 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank PF00023.30 OQR88651.1 - 1.3e-26 91.8 16.1 2e-05 24.8 0.3 7.8 7 0 0 7 7 7 6 Ankyrin repeat Ank_3 PF13606.6 OQR88651.1 - 3.1e-25 85.5 7.6 0.015 15.8 0.0 8.5 8 0 0 8 8 8 7 Ankyrin repeat Ank_5 PF13857.6 OQR88651.1 - 3.6e-25 87.7 10.3 3.3e-06 27.3 0.0 5.9 3 2 3 6 6 6 6 Ankyrin repeats (many copies) Ank_4 PF13637.6 OQR88651.1 - 5.1e-22 78.0 9.3 6.3e-07 29.8 0.2 7.2 4 3 4 8 8 8 5 Ankyrin repeats (many copies) FYVE PF01363.21 OQR88651.1 - 1.1e-14 54.3 9.9 2.9e-14 53.0 9.9 1.8 1 0 0 1 1 1 1 FYVE zinc finger IQ PF00612.27 OQR88651.1 - 0.0029 17.3 7.2 0.55 10.2 1.5 3.3 2 0 0 2 2 2 2 IQ calmodulin-binding motif AAA_22 PF13401.6 OQR88651.1 - 0.013 15.8 0.0 0.065 13.5 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 OQR88651.1 - 0.014 15.8 0.6 0.047 14.1 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain AAA_19 PF13245.6 OQR88651.1 - 0.024 14.9 0.0 0.48 10.7 0.0 2.7 2 0 0 2 2 2 0 AAA domain Sigma54_activat PF00158.26 OQR88651.1 - 0.031 14.0 0.0 0.07 12.8 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain RNA_helicase PF00910.22 OQR88651.1 - 0.12 12.7 0.0 0.46 10.9 0.0 2.0 1 0 0 1 1 1 0 RNA helicase DUF2767 PF10965.8 OQR88651.1 - 0.66 10.0 4.0 0.97 9.5 2.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2767) Zeta_toxin PF06414.12 OQR88651.1 - 2.6 7.3 10.1 0.74 9.1 0.1 2.7 2 0 0 2 2 2 0 Zeta toxin Asp-B-Hydro_N PF05279.11 OQR88651.1 - 3.6 7.6 8.7 8 6.5 8.7 1.5 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Pkinase_Tyr PF07714.17 OQR88654.1 - 6.8e-20 71.4 0.0 8.1e-20 71.2 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OQR88654.1 - 7.7e-20 71.4 0.0 8.9e-20 71.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQR88655.1 - 3.8e-33 114.9 0.0 4.7e-33 114.6 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OQR88655.1 - 3.4e-28 98.7 0.0 4.6e-28 98.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain HSF_DNA-bind PF00447.17 OQR88656.1 - 6.4e-31 106.8 0.6 1.1e-30 106.1 0.6 1.4 1 0 0 1 1 1 1 HSF-type DNA-binding CENP-F_leu_zip PF10473.9 OQR88656.1 - 0.0011 18.9 2.1 0.0019 18.2 2.1 1.4 1 0 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF4988 PF16378.5 OQR88656.1 - 0.0041 16.8 0.2 0.0065 16.2 0.2 1.2 1 0 0 1 1 1 1 Domain of unknown function TSC22 PF01166.18 OQR88656.1 - 0.0044 17.3 1.2 0.02 15.2 0.3 2.3 1 1 1 2 2 2 1 TSC-22/dip/bun family NPV_P10 PF05531.12 OQR88656.1 - 0.012 16.0 0.2 0.023 15.2 0.2 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein HAUS-augmin3 PF14932.6 OQR88656.1 - 0.024 14.2 1.5 0.036 13.6 1.5 1.3 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 YabA PF06156.13 OQR88656.1 - 0.024 15.3 1.7 0.043 14.5 1.7 1.5 1 0 0 1 1 1 0 Initiation control protein YabA SCO1-SenC PF02630.14 OQR88656.1 - 0.032 14.2 0.1 0.057 13.3 0.1 1.4 1 0 0 1 1 1 0 SCO1/SenC LPP PF04728.13 OQR88656.1 - 0.041 14.3 0.1 0.092 13.2 0.1 1.6 1 0 0 1 1 1 0 Lipoprotein leucine-zipper Synaptonemal_3 PF15191.6 OQR88656.1 - 0.068 12.9 0.1 0.3 10.9 0.1 2.1 1 1 1 2 2 2 0 Synaptonemal complex central element protein 3 DUF2730 PF10805.8 OQR88656.1 - 0.11 12.5 2.1 0.22 11.6 0.3 2.3 2 1 1 3 3 3 0 Protein of unknown function (DUF2730) TolA_bind_tri PF16331.5 OQR88656.1 - 0.12 12.5 2.2 0.15 12.1 1.0 1.8 1 1 0 1 1 1 0 TolA binding protein trimerisation DUF5082 PF16888.5 OQR88656.1 - 0.13 12.6 3.1 9.4 6.5 3.1 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF5082) ZapB PF06005.12 OQR88656.1 - 0.18 12.3 3.2 0.33 11.4 3.0 1.5 1 1 0 1 1 1 0 Cell division protein ZapB UBM PF14377.6 OQR88656.1 - 0.46 10.0 2.5 2.6 7.6 0.1 2.4 2 0 0 2 2 2 0 Ubiquitin binding region ABC_membrane PF00664.23 OQR88657.1 - 9.4e-21 74.7 12.7 1.2e-20 74.3 12.7 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 OQR88657.1 - 4.2e-18 66.2 0.0 8.1e-18 65.3 0.0 1.5 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 OQR88657.1 - 6.3e-06 25.8 0.2 0.0038 16.7 0.1 2.2 1 1 1 2 2 2 2 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 OQR88657.1 - 0.0028 17.6 0.1 0.0049 16.8 0.1 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_29 PF13555.6 OQR88657.1 - 0.0039 16.9 0.1 0.012 15.4 0.1 1.8 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.6 OQR88657.1 - 0.0075 16.5 0.0 0.22 11.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain Dynamin_N PF00350.23 OQR88657.1 - 0.012 15.7 0.0 0.021 14.9 0.0 1.4 1 0 0 1 1 1 0 Dynamin family AAA_21 PF13304.6 OQR88657.1 - 0.02 14.7 0.0 0.074 12.8 0.0 1.9 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 OQR88657.1 - 0.021 15.2 0.0 0.04 14.3 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain cobW PF02492.19 OQR88657.1 - 0.05 13.2 0.0 0.12 12.0 0.0 1.6 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_23 PF13476.6 OQR88657.1 - 0.058 13.9 0.1 0.1 13.1 0.1 1.3 1 0 0 1 1 1 0 AAA domain AAA_15 PF13175.6 OQR88657.1 - 0.079 12.7 0.0 0.12 12.1 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain MMR_HSR1 PF01926.23 OQR88657.1 - 0.093 12.8 0.0 0.21 11.7 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_25 PF13481.6 OQR88657.1 - 0.1 12.2 0.1 0.25 10.9 0.0 1.7 2 0 0 2 2 2 0 AAA domain Adeno_IVa2 PF02456.15 OQR88657.1 - 0.47 9.2 2.7 0.26 10.0 0.1 1.8 3 0 0 3 3 3 0 Adenovirus IVa2 protein ABC_membrane PF00664.23 OQR88658.1 - 3.1e-21 76.3 14.5 4.1e-21 75.9 14.5 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 OQR88658.1 - 0.00014 22.4 0.1 0.00027 21.4 0.1 1.6 1 0 0 1 1 1 1 ABC transporter AAA_29 PF13555.6 OQR88658.1 - 0.007 16.1 0.6 0.066 13.0 0.1 2.4 2 0 0 2 2 2 1 P-loop containing region of AAA domain SKN1 PF03935.15 OQR88660.1 - 7.2e-73 245.7 4.5 1.5e-72 244.6 4.5 1.4 1 1 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) FKS1_dom1 PF14288.6 OQR88660.1 - 2.3e-20 73.2 2.3 1.8e-19 70.4 2.3 2.2 1 1 0 1 1 1 1 1,3-beta-glucan synthase subunit FKS1, domain-1 Glyco_hydro_16 PF00722.21 OQR88660.1 - 2.4e-05 23.9 0.2 0.19 11.2 0.0 2.4 2 0 0 2 2 2 2 Glycosyl hydrolases family 16 Motile_Sperm PF00635.26 OQR88661.1 - 1.4e-18 66.8 5.8 2.2e-09 37.1 0.2 3.7 3 1 0 3 3 3 2 MSP (Major sperm protein) domain DnaJ PF00226.31 OQR88662.1 - 0.11 12.7 0.1 0.24 11.6 0.1 1.6 1 0 0 1 1 1 0 DnaJ domain START PF01852.19 OQR88663.1 - 1.6e-22 80.0 0.1 2e-22 79.7 0.1 1.0 1 0 0 1 1 1 1 START domain ORC5_C PF14630.6 OQR88664.1 - 0.03 13.8 0.1 0.075 12.5 0.1 1.6 1 1 0 1 1 1 0 Origin recognition complex (ORC) subunit 5 C-terminus RIB43A PF05914.12 OQR88665.1 - 2.8e-49 167.9 65.5 3.2e-49 167.7 65.5 1.0 1 0 0 1 1 1 1 RIB43A Ribosomal_S27e PF01667.17 OQR88666.1 - 8.3e-29 99.1 6.0 1e-28 98.8 6.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S27 DUF3795 PF12675.7 OQR88666.1 - 0.028 14.8 1.1 0.088 13.2 1.2 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3795) zf-CSL PF05207.13 OQR88666.1 - 0.058 13.1 2.2 0.12 12.2 2.2 1.6 1 1 0 1 1 1 0 CSL zinc finger DEAD PF00270.29 OQR88668.1 - 6.3e-49 166.1 0.0 1.5e-48 164.9 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OQR88668.1 - 1.7e-31 108.8 0.0 1.3e-28 99.6 0.0 2.7 3 0 0 3 3 3 2 Helicase conserved C-terminal domain ERCC3_RAD25_C PF16203.5 OQR88668.1 - 0.0023 17.2 0.0 0.0023 17.2 0.0 2.2 2 0 0 2 2 2 1 ERCC3/RAD25/XPB C-terminal helicase CMS1 PF14617.6 OQR88668.1 - 0.069 12.5 0.0 0.069 12.5 0.0 3.1 2 1 0 2 2 2 0 U3-containing 90S pre-ribosomal complex subunit Arrestin_C PF02752.22 OQR88668.1 - 0.44 11.0 3.8 1 9.8 3.8 1.6 1 0 0 1 1 1 0 Arrestin (or S-antigen), C-terminal domain ESM4 PF15952.5 OQR88668.1 - 0.52 10.7 5.2 1 9.7 5.2 1.4 1 0 0 1 1 1 0 Enhancer of split M4 family CP12 PF02672.15 OQR88668.1 - 2.8 8.7 9.3 7.3 7.4 9.3 1.8 1 0 0 1 1 1 0 CP12 domain Tyrosinase PF00264.20 OQR88670.1 - 5.2e-11 43.3 0.4 7.8e-08 32.9 0.0 2.3 1 1 1 2 2 2 2 Common central domain of tyrosinase Ricin_B_lectin PF00652.22 OQR88673.1 - 7.2e-20 71.5 9.1 2.4e-10 40.7 0.3 3.5 2 2 0 3 3 3 3 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.6 OQR88673.1 - 1.5e-05 25.7 2.2 0.59 10.9 0.1 4.6 3 1 0 4 4 4 1 Ricin-type beta-trefoil lectin domain-like CDtoxinA PF03498.14 OQR88673.1 - 2e-05 24.2 1.9 0.072 12.7 0.1 3.1 2 1 0 3 3 3 2 Cytolethal distending toxin A/C domain Peptidase_Mx PF15887.5 OQR88673.1 - 0.054 12.9 0.0 0.09 12.2 0.0 1.3 1 0 0 1 1 1 0 Putative zinc-binding metallo-peptidase ubiquitin PF00240.23 OQR88676.1 - 0.0017 18.1 1.1 0.0024 17.6 0.1 1.7 2 0 0 2 2 2 1 Ubiquitin family USP7_C2 PF14533.6 OQR88676.1 - 0.018 14.7 0.1 0.044 13.5 0.1 1.6 1 0 0 1 1 1 0 Ubiquitin-specific protease C-terminal UN_NPL4 PF11543.8 OQR88676.1 - 0.16 12.4 0.0 0.4 11.2 0.0 1.6 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 CorA PF01544.18 OQR88678.1 - 0.00012 21.5 21.2 0.00077 18.9 21.2 2.0 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein ABC_membrane PF00664.23 OQR88680.1 - 1.1e-47 163.1 19.1 1.4e-47 162.6 19.1 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 OQR88680.1 - 1.3e-34 119.6 0.0 3e-34 118.5 0.0 1.6 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 OQR88680.1 - 1.8e-06 27.5 3.8 1.5e-05 24.5 0.6 2.9 2 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain ABC_ATPase PF09818.9 OQR88680.1 - 0.0019 17.1 0.0 0.004 16.0 0.0 1.5 1 0 0 1 1 1 1 Predicted ATPase of the ABC class AAA_22 PF13401.6 OQR88680.1 - 0.0021 18.4 0.1 0.0087 16.3 0.1 2.0 1 1 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 OQR88680.1 - 0.004 17.1 0.1 0.04 13.8 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase AAA PF00004.29 OQR88680.1 - 0.0067 16.9 0.2 0.16 12.4 0.2 2.8 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 OQR88680.1 - 0.013 15.9 0.3 0.056 13.8 0.1 2.2 2 1 0 2 2 2 0 AAA ATPase domain AAA_30 PF13604.6 OQR88680.1 - 0.046 13.4 0.9 0.36 10.5 0.3 2.7 2 1 0 2 2 2 0 AAA domain AAA_29 PF13555.6 OQR88680.1 - 0.057 13.2 0.0 0.14 12.0 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain APS_kinase PF01583.20 OQR88680.1 - 0.08 12.8 0.0 0.19 11.6 0.0 1.6 1 0 0 1 1 1 0 Adenylylsulphate kinase SbcCD_C PF13558.6 OQR88680.1 - 0.12 12.6 3.2 0.36 11.1 0.6 2.8 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit PrgI PF12666.7 OQR88680.1 - 4.2 8.1 8.1 7.1 7.4 0.1 3.7 4 0 0 4 4 4 0 PrgI family protein Trypsin_2 PF13365.6 OQR88681.1 - 2.6e-13 51.1 0.1 4.7e-13 50.3 0.1 1.4 1 0 0 1 1 1 1 Trypsin-like peptidase domain Trypsin PF00089.26 OQR88681.1 - 1.8e-07 31.2 1.4 3.3e-07 30.3 1.4 1.4 1 0 0 1 1 1 1 Trypsin Peptidase_S46 PF10459.9 OQR88681.1 - 0.0024 16.6 2.0 0.077 11.6 0.1 2.6 3 0 0 3 3 3 2 Peptidase S46 IBR PF01485.21 OQR88683.1 - 3.4e-05 24.0 24.9 7.4e-05 22.9 9.1 4.1 3 1 0 3 3 3 2 IBR domain, a half RING-finger domain Phage_holin_4_2 PF04020.13 OQR88683.1 - 1.7 9.3 10.7 0.098 13.3 5.3 1.6 2 0 0 2 2 2 0 Mycobacterial 4 TMS phage holin, superfamily IV Pkinase_Tyr PF07714.17 OQR88686.1 - 1.4e-26 93.4 0.0 1.8e-26 93.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OQR88686.1 - 4.5e-21 75.4 0.0 6.1e-21 75.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain HypA PF01155.19 OQR88686.1 - 0.028 14.5 0.2 0.053 13.5 0.2 1.4 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA ABC_membrane PF00664.23 OQR88688.1 - 2.2e-51 175.1 20.6 3e-51 174.7 20.6 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 OQR88688.1 - 1.6e-30 106.4 0.1 8.9e-30 104.0 0.1 2.2 2 0 0 2 2 2 1 ABC transporter SMC_N PF02463.19 OQR88688.1 - 4.6e-07 29.5 0.6 2.9e-06 26.9 0.6 2.2 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain ABC_ATPase PF09818.9 OQR88688.1 - 0.00062 18.7 0.2 0.0014 17.5 0.2 1.5 1 1 0 1 1 1 1 Predicted ATPase of the ABC class AAA_22 PF13401.6 OQR88688.1 - 0.05 13.9 0.4 0.52 10.6 0.4 2.3 1 1 0 1 1 1 0 AAA domain AAA_5 PF07728.14 OQR88688.1 - 0.06 13.3 0.2 16 5.5 0.0 2.6 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) APS_kinase PF01583.20 OQR88688.1 - 0.11 12.3 0.0 0.27 11.1 0.0 1.6 1 0 0 1 1 1 0 Adenylylsulphate kinase Glycophorin_A PF01102.18 OQR88688.1 - 0.16 12.2 4.2 0.37 11.0 0.1 3.3 3 0 0 3 3 3 0 Glycophorin A RPN2_C PF18004.1 OQR88690.1 - 8e-40 136.4 6.6 8.5e-39 133.0 6.6 2.2 1 1 0 1 1 1 1 26S proteasome regulatory subunit RPN2 C-terminal domain PC_rep PF01851.22 OQR88690.1 - 8e-38 127.0 17.6 6.9e-08 32.6 0.0 8.3 8 0 0 8 8 8 6 Proteasome/cyclosome repeat HEAT_2 PF13646.6 OQR88690.1 - 4.7e-22 78.2 0.2 7.6e-14 51.9 0.0 4.6 3 2 1 4 4 4 3 HEAT repeats HEAT_EZ PF13513.6 OQR88690.1 - 1.6e-06 28.5 0.2 0.066 13.7 0.1 4.6 4 1 0 4 4 4 2 HEAT-like repeat HEAT PF02985.22 OQR88690.1 - 1.1e-05 25.3 0.5 0.85 10.1 0.1 4.9 4 0 0 4 4 4 2 HEAT repeat Cnd1 PF12717.7 OQR88690.1 - 1.6e-05 25.0 0.5 0.021 14.9 0.0 3.9 5 0 0 5 5 5 2 non-SMC mitotic condensation complex subunit 1 Methyltransf_2 PF00891.18 OQR88690.1 - 0.11 11.8 0.1 0.38 10.0 0.0 1.9 2 0 0 2 2 2 0 O-methyltransferase domain TPR_8 PF13181.6 OQR88694.1 - 1.1e-06 28.4 8.2 0.11 12.8 0.2 5.5 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.6 OQR88694.1 - 4.4e-06 26.9 12.8 0.099 12.9 0.1 4.6 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_7 PF13176.6 OQR88694.1 - 1.1e-05 25.1 5.3 0.063 13.3 0.3 4.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 OQR88694.1 - 1.3e-05 25.7 6.2 0.071 14.0 0.1 5.4 6 1 1 7 7 4 1 Tetratricopeptide repeat TPR_1 PF00515.28 OQR88694.1 - 1.7e-05 24.4 13.3 0.00082 19.1 0.5 4.6 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_2 PF07719.17 OQR88694.1 - 2e-05 24.3 17.1 0.0074 16.3 0.5 5.8 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_16 PF13432.6 OQR88694.1 - 0.00025 21.7 1.1 0.71 10.6 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat CENP-B_dimeris PF09026.10 OQR88694.1 - 0.0011 19.3 14.7 0.0024 18.2 14.7 1.5 1 0 0 1 1 1 1 Centromere protein B dimerisation domain TPR_11 PF13414.6 OQR88694.1 - 0.018 14.7 4.0 10 5.9 0.0 4.5 5 0 0 5 5 5 0 TPR repeat FAM176 PF14851.6 OQR88694.1 - 0.095 12.4 1.6 0.21 11.2 1.6 1.5 1 0 0 1 1 1 0 FAM176 family TPR_10 PF13374.6 OQR88694.1 - 0.24 11.3 5.8 14 5.7 0.1 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat NOA36 PF06524.12 OQR88694.1 - 0.25 10.6 11.2 0.39 10.0 11.2 1.2 1 0 0 1 1 1 0 NOA36 protein SDA1 PF05285.12 OQR88694.1 - 0.33 10.3 4.3 0.51 9.7 4.3 1.2 1 0 0 1 1 1 0 SDA1 RXT2_N PF08595.11 OQR88694.1 - 0.47 10.5 5.2 1 9.4 5.2 1.5 1 0 0 1 1 1 0 RXT2-like, N-terminal TPR_6 PF13174.6 OQR88694.1 - 1.4 9.7 13.7 7 7.5 0.3 5.8 7 0 0 7 7 6 0 Tetratricopeptide repeat TFIIA PF03153.13 OQR88694.1 - 1.6 8.6 7.9 0.087 12.8 2.4 1.6 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Cwf_Cwc_15 PF04889.12 OQR88694.1 - 4.5 6.9 13.7 9.3 5.9 13.7 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DNA_pol_phi PF04931.13 OQR88694.1 - 4.5 5.2 14.0 6.9 4.6 14.0 1.2 1 0 0 1 1 1 0 DNA polymerase phi Peptidase_C1 PF00112.23 OQR88696.1 - 1.1e-54 185.8 10.0 1.6e-54 185.3 10.0 1.2 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.15 OQR88696.1 - 0.0018 17.1 2.6 0.089 11.6 0.4 2.3 2 0 0 2 2 2 2 Peptidase C1-like family TraI_2_C PF07515.11 OQR88697.1 - 0.12 12.4 0.0 0.21 11.5 0.0 1.4 2 0 0 2 2 2 0 Putative conjugal transfer nickase/helicase TraI C-term Ank_2 PF12796.7 OQR88699.1 - 4.8e-62 206.5 20.7 2.3e-15 56.9 2.5 11.3 5 2 6 11 11 11 10 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQR88699.1 - 1.8e-42 143.2 26.8 1.2e-07 32.1 0.1 15.1 8 4 9 17 17 17 10 Ankyrin repeats (many copies) Ank PF00023.30 OQR88699.1 - 2.3e-39 132.2 39.6 0.0027 18.1 0.3 19.4 21 0 0 21 21 21 11 Ankyrin repeat Ank_3 PF13606.6 OQR88699.1 - 1.2e-38 126.6 28.9 0.0051 17.2 0.1 19.6 21 0 0 21 21 21 11 Ankyrin repeat Ank_5 PF13857.6 OQR88699.1 - 4.5e-38 128.8 32.3 1.4e-06 28.4 2.5 16.3 15 3 4 19 19 19 9 Ankyrin repeats (many copies) DUF3377 PF11857.8 OQR88701.1 - 0.026 14.5 0.2 0.044 13.7 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) P120R PF08062.11 OQR88701.1 - 0.43 11.0 3.9 0.86 10.0 3.9 1.5 1 0 0 1 1 1 0 P120R (NUC006) repeat SWIM PF04434.17 OQR88702.1 - 0.048 13.3 3.8 1.5 8.6 0.2 2.4 2 0 0 2 2 2 0 SWIM zinc finger Metallophos PF00149.28 OQR88703.1 - 1.7e-13 51.6 1.3 2.5e-13 51.0 1.3 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Pur_ac_phosph_N PF16656.5 OQR88703.1 - 1.3e-06 28.9 0.8 1.3e-06 28.9 0.8 2.1 2 0 0 2 2 2 1 Purple acid Phosphatase, N-terminal domain Metallophos_C PF14008.6 OQR88703.1 - 0.0065 17.3 0.1 0.025 15.4 0.1 2.1 1 0 0 1 1 1 1 Iron/zinc purple acid phosphatase-like protein C 2OG-FeII_Oxy_3 PF13640.6 OQR88704.1 - 1.4e-06 29.1 0.0 0.0018 19.1 0.0 2.4 2 0 0 2 2 2 2 2OG-Fe(II) oxygenase superfamily UCH PF00443.29 OQR88705.1 - 3.7e-51 174.1 0.1 5.7e-51 173.5 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase USP7_ICP0_bdg PF12436.8 OQR88705.1 - 1.2e-48 165.5 0.0 2.2e-48 164.7 0.0 1.4 1 0 0 1 1 1 1 ICP0-binding domain of Ubiquitin-specific protease 7 UCH_1 PF13423.6 OQR88705.1 - 4.1e-21 75.9 0.0 7.9e-21 75.0 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase USP7_C2 PF14533.6 OQR88705.1 - 6.9e-20 71.6 0.2 1.1e-18 67.8 0.0 2.7 3 0 0 3 3 3 1 Ubiquitin-specific protease C-terminal ubiquitin PF00240.23 OQR88705.1 - 0.0013 18.4 0.1 0.19 11.5 0.0 3.8 4 0 0 4 4 4 1 Ubiquitin family Ubiquitin_2 PF14560.6 OQR88705.1 - 0.0076 16.7 0.0 0.025 15.0 0.0 1.9 1 0 0 1 1 1 1 Ubiquitin-like domain Peptidase_C98 PF15499.6 OQR88705.1 - 0.067 12.6 1.1 0.32 10.4 0.0 2.6 3 0 0 3 3 3 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase Nop52 PF05997.12 OQR88708.1 - 2.3e-63 213.9 10.2 2.3e-63 213.9 10.2 2.2 2 1 0 2 2 2 1 Nucleolar protein,Nop52 COX6A PF02046.15 OQR88708.1 - 0.00072 20.0 0.7 0.00072 20.0 0.7 2.7 2 1 0 2 2 2 1 Cytochrome c oxidase subunit VIa Glyco_hydro_6 PF01341.17 OQR88710.1 - 8.1e-28 98.0 4.5 1.9e-27 96.8 4.5 1.5 1 1 0 1 1 1 1 Glycosyl hydrolases family 6 Tctex-1 PF03645.13 OQR88712.1 - 9.3e-27 93.3 0.2 1.1e-26 93.0 0.2 1.1 1 0 0 1 1 1 1 Tctex-1 family TipAS PF07739.13 OQR88712.1 - 0.06 13.9 0.0 0.072 13.6 0.0 1.1 1 0 0 1 1 1 0 TipAS antibiotic-recognition domain Glutaminase PF04960.15 OQR88714.1 - 4.6e-40 137.6 0.4 1e-39 136.4 0.2 1.6 2 0 0 2 2 2 1 Glutaminase EF-hand_14 PF17959.1 OQR88714.1 - 2.2e-09 37.5 0.0 8.8e-09 35.6 0.0 2.1 1 1 0 1 1 1 1 EF-hand domain EF-hand_1 PF00036.32 OQR88714.1 - 0.0066 15.9 0.1 0.033 13.7 0.1 2.2 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 OQR88714.1 - 0.017 15.0 0.5 0.059 13.3 0.2 2.1 2 0 0 2 2 2 0 EF-hand domain EF-hand_5 PF13202.6 OQR88714.1 - 0.051 13.1 0.1 0.14 11.7 0.1 1.8 1 0 0 1 1 1 0 EF hand EF-hand_7 PF13499.6 OQR88714.1 - 0.062 13.8 0.1 0.22 12.0 0.0 2.0 2 0 0 2 2 2 0 EF-hand domain pair COPI_assoc PF08507.10 OQR88716.1 - 4.9e-12 46.0 16.3 5.7e-12 45.8 16.3 1.0 1 0 0 1 1 1 1 COPI associated protein Fringe PF02434.16 OQR88717.1 - 3e-12 46.5 0.0 4.2e-12 46.0 0.0 1.2 1 0 0 1 1 1 1 Fringe-like Galactosyl_T PF01762.21 OQR88717.1 - 0.006 16.4 0.0 0.015 15.1 0.0 1.8 2 0 0 2 2 2 1 Galactosyltransferase Peptidase_C2 PF00648.21 OQR88718.1 - 3.1e-42 144.6 0.0 5e-42 143.9 0.0 1.3 1 0 0 1 1 1 1 Calpain family cysteine protease Calpain_III PF01067.22 OQR88718.1 - 2.8e-22 79.5 0.8 0.00039 20.7 0.0 5.0 4 1 0 4 4 4 4 Calpain large subunit, domain III MIT PF04212.18 OQR88718.1 - 1.4e-05 25.1 6.7 0.004 17.2 1.2 2.4 2 0 0 2 2 2 2 MIT (microtubule interacting and transport) domain Prefoldin_2 PF01920.20 OQR88719.1 - 2.4e-19 69.2 3.2 2.6e-19 69.1 3.2 1.0 1 0 0 1 1 1 1 Prefoldin subunit DASH_Dad3 PF08656.10 OQR88719.1 - 0.00034 20.6 0.9 0.00067 19.7 0.9 1.5 1 0 0 1 1 1 1 DASH complex subunit Dad3 DivIVA PF05103.13 OQR88719.1 - 0.0048 17.0 3.7 0.022 14.9 1.9 2.0 2 0 0 2 2 2 1 DivIVA protein GNT-I PF03071.15 OQR88719.1 - 0.0058 15.4 0.5 0.0068 15.2 0.5 1.0 1 0 0 1 1 1 1 GNT-I family ABC_tran_CTD PF16326.5 OQR88719.1 - 0.0086 16.3 2.1 1.8 8.9 1.2 2.2 2 0 0 2 2 2 2 ABC transporter C-terminal domain CENP-F_leu_zip PF10473.9 OQR88719.1 - 0.029 14.4 1.2 0.029 14.4 1.2 1.9 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ZapB PF06005.12 OQR88719.1 - 0.029 14.8 1.6 0.029 14.8 1.6 1.9 2 0 0 2 2 2 0 Cell division protein ZapB DUF4061 PF13270.6 OQR88719.1 - 0.083 13.2 1.5 0.13 12.6 1.5 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4061) PhyH PF05721.13 OQR88719.1 - 0.089 13.0 0.1 0.096 12.9 0.1 1.0 1 0 0 1 1 1 0 Phytanoyl-CoA dioxygenase (PhyH) DUF1488 PF07369.11 OQR88719.1 - 0.09 12.8 0.1 0.19 11.8 0.1 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1488) GAS PF13851.6 OQR88719.1 - 0.24 10.7 6.9 1.5 8.1 6.9 1.9 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding COG2 PF06148.11 OQR88719.1 - 0.31 11.1 4.6 3.2 7.9 0.2 2.1 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Ank_2 PF12796.7 OQR88721.1 - 9.5e-52 173.5 10.8 1.1e-17 64.3 0.5 5.1 2 2 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQR88721.1 - 7.1e-46 154.0 6.7 7.2e-09 36.0 0.1 6.9 4 2 3 7 7 7 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQR88721.1 - 4.4e-42 137.2 11.7 0.00044 20.5 0.1 9.5 10 0 0 10 10 10 9 Ankyrin repeat Ank PF00023.30 OQR88721.1 - 1.2e-40 136.2 19.2 0.00011 22.5 0.2 9.9 9 1 1 10 10 10 9 Ankyrin repeat Ank_5 PF13857.6 OQR88721.1 - 4.7e-37 125.6 15.6 1.1e-08 35.1 0.1 7.6 2 2 6 8 8 8 8 Ankyrin repeats (many copies) DHHC PF01529.20 OQR88726.1 - 1.8e-15 57.3 1.5 1.8e-15 57.3 1.5 2.1 2 0 0 2 2 2 2 DHHC palmitoyltransferase COX15-CtaA PF02628.15 OQR88726.1 - 0.042 12.9 0.5 0.059 12.4 0.5 1.1 1 0 0 1 1 1 0 Cytochrome oxidase assembly protein SKN1 PF03935.15 OQR88728.1 - 1.1e-58 198.9 20.6 5.9e-25 87.6 1.3 5.1 4 2 0 4 4 4 4 Beta-glucan synthesis-associated protein (SKN1) DUF5454 PF17535.2 OQR88728.1 - 0.041 13.3 0.2 0.077 12.4 0.2 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5454) EB PF01683.18 OQR88728.1 - 0.062 13.6 3.3 0.069 13.4 1.6 2.0 2 0 0 2 2 2 0 EB module Nodulin_late PF07127.11 OQR88728.1 - 9.5 6.6 5.7 1.3 9.4 0.5 2.3 3 0 0 3 3 3 0 Late nodulin protein Pkinase PF00069.25 OQR88729.1 - 6e-29 101.2 4.5 4.4e-18 65.6 2.6 2.0 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OQR88729.1 - 3.8e-18 65.7 2.3 1.5e-13 50.6 1.2 2.1 1 1 1 2 2 2 2 Protein tyrosine kinase Kdo PF06293.14 OQR88729.1 - 9.1e-06 25.2 0.1 1.3e-05 24.7 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 OQR88729.1 - 0.0053 15.6 0.1 0.0068 15.2 0.1 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 OQR88729.1 - 0.014 14.7 0.5 0.2 11.0 0.0 2.0 1 1 0 2 2 2 0 Kinase-like PhzC-PhzF PF02567.16 OQR88731.1 - 1.2e-57 195.6 0.0 2.3e-57 194.6 0.0 1.5 1 0 0 1 1 1 1 Phenazine biosynthesis-like protein UCH PF00443.29 OQR88731.1 - 1.6e-29 103.2 0.0 6.5e-29 101.2 0.0 1.9 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-RanBP PF00641.18 OQR88731.1 - 7.1e-20 70.0 41.7 2.8e-07 29.7 3.9 4.9 4 0 0 4 4 4 4 Zn-finger in Ran binding protein and others Acetyltransf_1 PF00583.25 OQR88731.1 - 6.1e-13 49.0 0.0 1.3e-12 47.9 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 OQR88731.1 - 1.8e-11 44.1 0.0 4.6e-11 42.8 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain UCH_1 PF13423.6 OQR88731.1 - 8.7e-11 42.0 6.2 3e-07 30.3 0.0 3.9 3 1 0 3 3 3 2 Ubiquitin carboxyl-terminal hydrolase Acetyltransf_7 PF13508.7 OQR88731.1 - 1.4e-08 35.1 0.1 3.5e-08 33.8 0.1 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Laminin_G_3 PF13385.6 OQR88731.1 - 8.1e-07 29.3 0.0 1.3e-05 25.4 0.0 2.8 2 0 0 2 2 2 1 Concanavalin A-like lectin/glucanases superfamily Acetyltransf_9 PF13527.7 OQR88731.1 - 1.7e-05 24.9 0.0 3.5e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF2464 PF10240.9 OQR88731.1 - 0.00051 19.7 1.4 0.17 11.4 0.0 3.8 4 0 0 4 4 4 1 Multivesicular body subunit 12 Acetyltransf_CG PF14542.6 OQR88731.1 - 0.00068 19.7 0.0 0.0018 18.4 0.0 1.6 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_15 PF17013.5 OQR88731.1 - 0.0073 15.8 0.0 0.014 14.9 0.0 1.3 1 0 0 1 1 1 1 Putative acetyl-transferase Acetyltransf_13 PF13880.6 OQR88731.1 - 0.021 14.8 0.0 0.076 13.0 0.0 1.9 1 0 0 1 1 1 0 ESCO1/2 acetyl-transferase DZR PF12773.7 OQR88731.1 - 0.15 12.1 41.5 1.1 9.4 8.9 6.3 6 0 0 6 6 6 0 Double zinc ribbon SKN1 PF03935.15 OQR88732.1 - 5.9e-59 199.8 21.7 6e-28 97.5 0.8 5.2 4 2 0 4 4 4 4 Beta-glucan synthesis-associated protein (SKN1) EB PF01683.18 OQR88732.1 - 0.015 15.6 3.3 0.016 15.5 1.1 2.2 2 0 0 2 2 2 0 EB module Albumin_I_a PF16720.5 OQR88732.1 - 3 7.8 4.6 4.2 7.4 1.4 2.6 1 1 1 2 2 2 0 Albumin I chain a EGF_2 PF07974.13 OQR88733.1 - 0.44 11.0 8.7 1.1 9.7 8.7 1.7 1 1 0 1 1 1 0 EGF-like domain Nodulin_late PF07127.11 OQR88733.1 - 0.57 10.6 4.5 0.67 10.3 3.1 1.8 2 0 0 2 2 2 0 Late nodulin protein Peptidase_C12 PF01088.21 OQR88734.1 - 0.085 12.6 0.0 0.085 12.6 0.0 1.1 1 0 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase, family 1 Ank_2 PF12796.7 OQR88737.1 - 1.3e-60 201.9 65.1 2.8e-10 40.7 1.4 8.8 1 1 9 11 11 11 11 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQR88737.1 - 5.5e-48 160.8 31.7 1.4e-05 25.6 0.5 11.9 6 3 8 14 14 14 14 Ankyrin repeats (many copies) Ank_5 PF13857.6 OQR88737.1 - 2.6e-41 139.1 34.5 9.4e-05 22.6 0.1 17.1 3 2 15 18 18 18 14 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQR88737.1 - 2e-28 95.3 24.3 2.5 8.9 0.0 18.4 17 2 2 19 19 19 6 Ankyrin repeat Ank PF00023.30 OQR88737.1 - 8.1e-09 35.5 20.8 34 5.1 0.0 13.5 9 4 3 12 12 12 0 Ankyrin repeat DUF5049 PF16468.5 OQR88737.1 - 2e-06 27.6 14.7 45 4.0 0.1 11.6 8 2 5 13 13 13 0 Domain of unknown function (DUF5049) CNOT1_HEAT PF16418.5 OQR88737.1 - 0.0016 18.5 0.0 0.66 10.0 0.0 3.9 3 0 0 3 3 3 1 CCR4-NOT transcription complex subunit 1 HEAT repeat AhpC-TSA PF00578.21 OQR88737.1 - 0.016 15.1 1.1 29 4.6 0.0 4.7 1 1 4 6 6 6 0 AhpC/TSA family HA PF03457.14 OQR88737.1 - 0.16 12.4 2.5 24 5.4 0.0 4.7 4 1 0 4 4 4 0 Helicase associated domain Ank_2 PF12796.7 OQR88738.1 - 5.7e-14 52.5 1.5 2.7e-07 31.1 0.2 2.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQR88738.1 - 4.9e-13 49.3 4.0 9.4e-05 22.9 0.2 3.3 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 OQR88738.1 - 5.8e-12 45.6 2.5 0.0078 16.5 0.1 4.2 3 2 1 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQR88738.1 - 6.7e-10 38.4 0.6 0.13 12.9 0.0 4.4 5 0 0 5 5 5 3 Ankyrin repeat Ank PF00023.30 OQR88738.1 - 1e-05 25.7 0.6 0.72 10.4 0.0 4.1 4 1 0 4 4 4 2 Ankyrin repeat HA PF03457.14 OQR88738.1 - 0.00038 20.7 0.1 0.0075 16.6 0.1 2.3 2 0 0 2 2 2 1 Helicase associated domain DUF5049 PF16468.5 OQR88738.1 - 0.022 14.6 4.6 10 6.1 0.1 4.0 3 2 2 5 5 5 0 Domain of unknown function (DUF5049) Ank_4 PF13637.6 OQR88739.1 - 2.6e-45 152.2 8.4 7.2e-08 32.8 0.0 9.1 6 3 4 10 10 10 9 Ankyrin repeats (many copies) Ank_2 PF12796.7 OQR88739.1 - 9.7e-42 141.5 15.3 7.4e-09 36.1 0.1 6.5 1 1 5 7 7 7 7 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OQR88739.1 - 4.2e-39 132.1 9.1 0.003 17.8 0.0 12.8 2 2 12 14 14 14 11 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQR88739.1 - 1e-23 80.8 4.7 0.27 11.9 0.0 13.8 13 1 2 15 15 15 5 Ankyrin repeat Ank PF00023.30 OQR88739.1 - 2.2e-06 27.9 6.7 81 3.9 0.0 10.0 6 3 2 8 8 8 0 Ankyrin repeat DUF5049 PF16468.5 OQR88739.1 - 2.5e-05 24.1 6.8 5.5 7.0 0.0 8.4 8 1 3 11 11 11 1 Domain of unknown function (DUF5049) ENTH PF01417.20 OQR88739.1 - 0.00048 20.2 1.1 3.9 7.6 0.0 4.5 5 0 0 5 5 5 2 ENTH domain DUF1843 PF08898.10 OQR88739.1 - 0.0014 19.0 3.8 13 6.4 0.0 6.7 9 0 0 9 9 9 1 Domain of unknown function (DUF1843) YicC_N PF03755.13 OQR88739.1 - 0.055 13.9 0.3 0.24 11.8 0.0 2.1 3 0 0 3 3 3 0 YicC-like family, N-terminal region Pkinase PF00069.25 OQR88740.1 - 1.6e-39 135.9 0.4 2.1e-38 132.2 0.4 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQR88740.1 - 1.1e-15 57.7 0.1 2.3e-15 56.6 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OQR88740.1 - 0.00027 20.3 0.0 0.00035 20.0 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 OQR88740.1 - 0.0033 16.3 0.0 0.0047 15.7 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase YrbL-PhoP_reg PF10707.9 OQR88740.1 - 0.017 14.6 0.0 0.025 14.1 0.0 1.3 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Pox_ser-thr_kin PF05445.11 OQR88740.1 - 0.03 13.3 0.0 0.042 12.8 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Kdo PF06293.14 OQR88740.1 - 0.12 11.7 0.0 0.17 11.3 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 OQR88741.1 - 2.8e-09 36.7 0.0 3.8e-09 36.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQR88741.1 - 0.012 14.9 0.0 0.015 14.6 0.0 1.1 1 0 0 1 1 1 0 Protein tyrosine kinase SHE3 PF17078.5 OQR88742.1 - 0.022 14.4 39.6 1.3 8.7 4.9 4.3 3 1 1 4 4 4 0 SWI5-dependent HO expression protein 3 YejG PF13989.6 OQR88742.1 - 0.79 10.2 5.8 0.75 10.3 0.5 3.2 2 1 2 4 4 4 0 YejG-like protein DUF3209 PF11483.8 OQR88742.1 - 8.4 6.9 11.4 2.6 8.5 1.1 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3209) DDT PF02791.17 OQR88744.1 - 9.7e-15 54.6 0.9 2.1e-14 53.6 0.9 1.6 1 0 0 1 1 1 1 DDT domain PHD PF00628.29 OQR88744.1 - 1.4e-11 44.1 8.8 3.1e-11 43.0 8.8 1.7 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.6 OQR88744.1 - 0.0063 16.7 4.3 0.02 15.2 4.3 2.0 1 1 0 1 1 1 1 PHD-like zinc-binding domain PHD_2 PF13831.6 OQR88744.1 - 0.018 14.6 6.3 0.035 13.6 1.2 2.4 2 0 0 2 2 2 0 PHD-finger WHIM1 PF15612.6 OQR88744.1 - 0.024 14.2 0.0 0.07 12.7 0.0 1.8 1 0 0 1 1 1 0 WSTF, HB1, Itc1p, MBD9 motif 1 DUF1364 PF07102.12 OQR88744.1 - 0.14 12.0 1.1 0.33 10.8 1.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1364) V_ATPase_I PF01496.19 OQR88744.1 - 1.1 7.1 8.8 0.026 12.4 2.5 1.4 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family C1_1 PF00130.22 OQR88744.1 - 6.4 6.8 10.7 2.1 8.3 4.6 2.4 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) COMM_domain PF07258.14 OQR88748.1 - 9.2e-15 54.5 0.1 2e-14 53.4 0.1 1.5 1 0 0 1 1 1 1 COMM domain DUF1818 PF08848.11 OQR88748.1 - 0.49 10.5 5.0 3.1 7.9 0.0 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF1818) Metallophos PF00149.28 OQR88749.1 - 8.6e-13 49.3 0.3 8.6e-13 49.3 0.3 1.5 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 OQR88749.1 - 0.00068 19.9 0.1 0.018 15.2 0.0 2.2 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase superfamily domain Peptidase_U57 PF05582.12 OQR88749.1 - 0.068 12.4 0.0 0.1 11.9 0.0 1.3 1 0 0 1 1 1 0 YabG peptidase U57 Aminotran_5 PF00266.19 OQR88751.1 - 2.5e-34 118.8 0.0 3.4e-34 118.4 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V PKD_channel PF08016.12 OQR88753.1 - 7.1e-08 31.6 8.7 7.1e-08 31.6 8.7 2.9 2 1 1 3 3 3 2 Polycystin cation channel Ion_trans PF00520.31 OQR88753.1 - 1e-06 28.2 23.4 1e-06 28.2 23.4 2.1 1 1 1 2 2 2 1 Ion transport protein Metallophos_C PF14008.6 OQR88754.1 - 1.8e-05 25.5 0.2 0.0027 18.5 0.0 2.8 2 0 0 2 2 2 2 Iron/zinc purple acid phosphatase-like protein C SIS PF01380.22 OQR88761.1 - 1.3e-32 112.4 0.1 1.1e-15 57.7 0.0 2.5 2 0 0 2 2 2 2 SIS domain Tropomyosin PF00261.20 OQR88762.1 - 0.0068 15.8 23.0 0.013 14.9 23.0 1.3 1 0 0 1 1 1 1 Tropomyosin BssS PF13991.6 OQR88762.1 - 0.061 13.4 0.2 0.51 10.4 0.3 2.5 2 0 0 2 2 2 0 BssS protein family DUF745 PF05335.13 OQR88762.1 - 0.082 12.6 19.2 0.026 14.3 8.2 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF745) HIP1_clath_bdg PF16515.5 OQR88762.1 - 0.35 11.5 28.8 2.2 8.9 6.2 3.8 1 1 2 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Spc7 PF08317.11 OQR88762.1 - 1.4 7.8 22.0 2.6 6.8 22.0 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein UPF0449 PF15136.6 OQR88762.1 - 3.8 8.1 20.2 0.7 10.4 2.7 4.3 2 1 0 3 3 3 0 Uncharacterised protein family UPF0449 SHIPPO-rpt PF07004.12 OQR88762.1 - 4.1 8.5 6.0 0.9 10.6 0.2 2.9 4 0 0 4 4 4 0 Sperm-tail PG-rich repeat Laminin_II PF06009.12 OQR88762.1 - 5.2 7.1 19.0 8 6.5 5.8 2.6 1 1 1 2 2 2 0 Laminin Domain II ADH_zinc_N PF00107.26 OQR88768.1 - 7.3e-25 87.4 0.2 3.5e-24 85.2 0.1 2.0 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 OQR88768.1 - 1.4e-15 58.5 0.0 3.8e-15 57.1 0.0 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 OQR88768.1 - 2.1e-12 46.9 0.1 7.7e-11 41.9 0.0 2.6 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain LPP PF04728.13 OQR88769.1 - 0.27 11.6 0.0 0.27 11.6 0.0 10.8 10 1 0 10 10 10 0 Lipoprotein leucine-zipper Cu-oxidase_2 PF07731.14 OQR88771.1 - 1.4e-19 70.2 1.5 1.4e-19 70.2 1.5 2.9 3 1 0 3 3 3 1 Multicopper oxidase Cu-oxidase_3 PF07732.15 OQR88771.1 - 2.8e-12 46.7 1.0 5.9e-10 39.2 1.5 3.1 2 1 0 2 2 2 1 Multicopper oxidase DUF3328 PF11807.8 OQR88771.1 - 0.14 11.9 0.2 0.25 11.1 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3328) DDE_Tnp_4 PF13359.6 OQR88773.1 - 2.3e-11 43.6 0.2 4e-11 42.8 0.2 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 OQR88773.1 - 0.00013 21.6 0.1 0.00022 20.9 0.1 1.3 1 0 0 1 1 1 1 Plant transposon protein RVT_1 PF00078.27 OQR88776.1 - 7.5e-15 55.1 0.0 1.9e-14 53.8 0.0 1.7 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF4670 PF15709.5 OQR88777.1 - 0.0088 15.4 9.6 0.0096 15.3 9.6 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4670) Tho2 PF11262.8 OQR88780.1 - 1.3e-78 264.2 2.0 1.3e-78 264.2 2.0 2.8 2 1 1 3 3 3 1 Transcription factor/nuclear export subunit protein 2 THOC2_N PF16134.5 OQR88780.1 - 6.3e-55 187.0 5.9 3.2e-29 102.1 3.8 4.4 1 1 1 2 2 2 2 THO complex subunit 2 N-terminus Thoc2 PF11732.8 OQR88780.1 - 1.2e-26 92.5 0.4 3.6e-26 91.0 0.0 2.1 2 0 0 2 2 2 1 Transcription- and export-related complex subunit A_deaminase PF00962.22 OQR88780.1 - 1.3e-23 83.9 0.2 3.1e-23 82.6 0.2 1.7 1 0 0 1 1 1 1 Adenosine/AMP deaminase RGS PF00615.19 OQR88781.1 - 4.2e-06 27.0 0.0 6.4e-06 26.4 0.0 1.3 1 0 0 1 1 1 1 Regulator of G protein signaling domain Com_YlbF PF06133.11 OQR88784.1 - 0.015 15.9 6.3 0.028 15.0 6.3 1.4 1 0 0 1 1 1 0 Control of competence regulator ComK, YlbF/YmcA DUF3573 PF12097.8 OQR88784.1 - 0.11 11.3 2.2 0.14 11.0 2.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) DUF2654 PF10849.8 OQR88784.1 - 0.18 12.1 0.2 0.18 12.1 0.2 2.5 3 1 1 4 4 4 0 Protein of unknown function (DUF2654) GAS PF13851.6 OQR88784.1 - 0.7 9.2 12.7 3.2 7.1 2.2 2.1 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding WGR PF05406.15 OQR88785.1 - 2.5e-26 91.6 1.6 2.5e-26 91.6 1.6 2.1 2 0 0 2 2 2 1 WGR domain BRCT PF00533.26 OQR88785.1 - 2.8e-23 82.1 0.0 6.8e-11 42.4 0.0 2.8 2 0 0 2 2 2 2 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 OQR88785.1 - 1.1e-11 44.5 2.6 4.9e-05 23.2 0.3 2.5 2 0 0 2 2 2 2 twin BRCT domain PARP_reg PF02877.14 OQR88785.1 - 1.2e-11 44.9 0.0 2.8e-11 43.7 0.0 1.6 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase, regulatory domain ART PF01129.18 OQR88785.1 - 1e-10 41.3 0.0 2.2e-10 40.2 0.0 1.5 1 0 0 1 1 1 1 NAD:arginine ADP-ribosyltransferase ADPrib_exo_Tox PF03496.14 OQR88785.1 - 0.0024 17.2 0.0 0.023 14.1 0.0 2.4 1 1 0 1 1 1 1 ADP-ribosyltransferase exoenzyme BRCT_2 PF16589.5 OQR88785.1 - 0.0042 17.5 1.6 1.7 9.1 0.0 3.2 3 0 0 3 3 3 2 BRCT domain, a BRCA1 C-terminus domain Pox_Ag35 PF03286.14 OQR88785.1 - 0.024 14.4 8.7 0.063 13.1 8.7 1.6 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Interferon PF00143.19 OQR88785.1 - 0.35 11.0 1.6 2.7 8.1 0.2 2.5 2 0 0 2 2 2 0 Interferon alpha/beta domain FAM176 PF14851.6 OQR88785.1 - 1.6 8.4 4.9 4.8 6.8 4.9 1.8 1 0 0 1 1 1 0 FAM176 family Tcf25 PF04910.14 OQR88787.1 - 0.012 14.8 0.5 0.016 14.3 0.5 1.2 1 0 0 1 1 1 0 Transcriptional repressor TCF25 GABP-alpha PF11620.8 OQR88787.1 - 0.076 13.2 0.8 0.19 12.0 0.8 1.7 1 0 0 1 1 1 0 GA-binding protein alpha chain T_Ag_DNA_bind PF02217.16 OQR88787.1 - 0.16 12.6 1.3 0.35 11.5 0.4 2.0 2 0 0 2 2 2 0 Origin of replication binding protein LRR_8 PF13855.6 OQR88790.1 - 1.4e-22 79.2 38.7 1.1e-08 34.7 1.0 6.6 5 2 1 7 7 7 6 Leucine rich repeat LRR_4 PF12799.7 OQR88790.1 - 2.1e-17 62.9 36.5 0.0053 17.1 0.7 8.2 7 1 2 9 9 9 7 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 OQR88790.1 - 0.031 13.8 13.3 3.4 7.1 0.1 4.8 5 0 0 5 5 5 0 Leucine-rich repeat LRR_1 PF00560.33 OQR88790.1 - 0.26 12.0 18.6 89 4.3 0.3 9.9 9 1 0 9 9 9 0 Leucine Rich Repeat LRR_6 PF13516.6 OQR88790.1 - 0.6 10.3 30.2 15 6.0 0.0 9.0 10 0 0 10 10 10 0 Leucine Rich repeat LRR_8 PF13855.6 OQR88792.1 - 1.2e-05 25.0 27.3 6.1e-05 22.7 3.6 4.3 1 1 4 5 5 5 3 Leucine rich repeat LRR_4 PF12799.7 OQR88792.1 - 0.00014 22.2 3.5 0.00014 22.2 3.5 4.5 2 1 3 5 5 5 2 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 OQR88792.1 - 0.013 15.0 1.4 0.013 15.0 1.4 2.1 1 1 0 2 2 2 0 Leucine-rich repeat DUF4317 PF14199.6 OQR88792.1 - 0.17 11.0 1.5 0.17 11.0 0.1 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4317) LRR_6 PF13516.6 OQR88792.1 - 0.49 10.6 0.1 0.49 10.6 0.1 5.5 6 0 0 6 6 6 0 Leucine Rich repeat HEAT PF02985.22 OQR88793.1 - 1.3e-13 50.0 3.8 0.0048 17.1 0.0 5.7 5 0 0 5 5 5 4 HEAT repeat HEAT_2 PF13646.6 OQR88793.1 - 6e-12 45.8 0.0 9.1e-05 22.8 0.0 4.1 2 2 1 3 3 3 2 HEAT repeats HEAT_EZ PF13513.6 OQR88793.1 - 6e-08 33.0 1.0 0.041 14.4 0.0 4.5 5 0 0 5 5 5 3 HEAT-like repeat Cnd1 PF12717.7 OQR88793.1 - 3e-05 24.1 0.0 0.18 11.8 0.0 3.1 2 1 1 4 4 4 3 non-SMC mitotic condensation complex subunit 1 CLASP_N PF12348.8 OQR88793.1 - 0.0023 17.5 0.0 0.97 9.0 0.0 2.2 2 0 0 2 2 2 2 CLASP N terminal Adaptin_N PF01602.20 OQR88793.1 - 0.0047 15.6 0.1 0.88 8.1 0.0 2.5 3 0 0 3 3 3 2 Adaptin N terminal region DUF4042 PF13251.6 OQR88793.1 - 0.0055 16.4 0.1 0.067 12.9 0.0 2.7 2 1 2 4 4 4 1 Domain of unknown function (DUF4042) Arm PF00514.23 OQR88793.1 - 3.5 7.8 5.7 6.3 7.0 0.0 3.5 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat LRR_8 PF13855.6 OQR88794.1 - 0.0019 17.9 0.1 0.0045 16.7 0.1 1.7 1 0 0 1 1 1 1 Leucine rich repeat LRR_4 PF12799.7 OQR88794.1 - 0.023 15.1 0.4 0.07 13.6 0.4 1.8 1 0 0 1 1 1 0 Leucine Rich repeats (2 copies) K_oxygenase PF13434.6 OQR88794.1 - 0.21 10.7 0.0 0.31 10.1 0.0 1.2 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) Acyl_transf_1 PF00698.21 OQR88796.1 - 1.1e-08 35.0 0.1 1.1e-08 34.9 0.1 1.1 1 0 0 1 1 1 1 Acyl transferase domain AA_permease_2 PF13520.6 OQR88797.1 - 0.093 11.5 10.6 0.11 11.3 7.1 1.9 1 1 0 1 1 1 0 Amino acid permease Pkinase PF00069.25 OQR88798.1 - 5.4e-52 176.8 0.3 7.3e-30 104.2 0.0 3.7 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OQR88798.1 - 2.2e-50 171.4 0.0 1.6e-25 89.9 0.0 3.8 2 1 0 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 OQR88798.1 - 0.00028 19.8 0.0 0.0038 16.1 0.0 2.0 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 OQR88798.1 - 0.0019 18.2 0.0 0.89 9.4 0.0 2.4 2 0 0 2 2 2 2 Phosphotransferase enzyme family EphA2_TM PF14575.6 OQR88798.1 - 0.0061 17.4 0.1 0.019 15.8 0.1 1.8 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain Protocadherin PF08374.11 OQR88798.1 - 0.019 15.0 0.0 0.049 13.6 0.0 1.6 1 0 0 1 1 1 0 Protocadherin Haspin_kinase PF12330.8 OQR88798.1 - 0.02 13.9 0.0 14 4.5 0.0 3.1 2 1 0 3 3 3 0 Haspin like kinase domain Kinase-like PF14531.6 OQR88798.1 - 0.061 12.6 0.0 0.64 9.3 0.0 2.5 3 0 0 3 3 3 0 Kinase-like Adeno_E3_CR2 PF02439.15 OQR88798.1 - 0.062 13.1 1.5 0.13 12.0 1.5 1.5 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Glycophorin_A PF01102.18 OQR88798.1 - 0.13 12.5 0.0 0.3 11.4 0.0 1.5 1 0 0 1 1 1 0 Glycophorin A PRIMA1 PF16101.5 OQR88798.1 - 0.15 12.1 0.0 0.48 10.5 0.0 1.8 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 TLC PF03219.14 OQR88799.1 - 3.1e-16 59.2 17.9 4.6e-10 38.8 3.0 3.9 1 1 1 3 3 3 3 TLC ATP/ADP transporter MFS_1 PF07690.16 OQR88799.1 - 7.1e-07 28.5 13.7 7.1e-07 28.5 13.7 2.6 1 1 0 2 2 2 1 Major Facilitator Superfamily PMSR PF01625.21 OQR88800.1 - 1.9e-121 401.6 12.0 5.6e-61 205.2 3.1 2.0 2 0 0 2 2 2 2 Peptide methionine sulfoxide reductase Vsr PF03852.15 OQR88800.1 - 0.026 14.4 0.0 4.2 7.3 0.0 2.6 2 0 0 2 2 2 0 DNA mismatch endonuclease Vsr CAF1 PF04857.20 OQR88800.1 - 0.03 13.5 3.3 0.89 8.7 0.6 2.1 1 1 0 2 2 2 0 CAF1 family ribonuclease NTR2 PF15458.6 OQR88800.1 - 0.059 12.9 0.1 3.2 7.2 0.0 2.1 2 0 0 2 2 2 0 Nineteen complex-related protein 2 Pox_F17 PF04767.12 OQR88801.1 - 0.0089 16.5 0.0 0.02 15.4 0.0 1.6 1 0 0 1 1 1 1 DNA-binding 11 kDa phosphoprotein RVT_1 PF00078.27 OQR88803.1 - 8.3e-15 54.9 0.0 1.3e-07 31.4 0.0 2.3 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) zf-RVT PF13966.6 OQR88803.1 - 0.038 14.7 0.3 0.038 14.7 0.3 2.3 2 0 0 2 2 2 0 zinc-binding in reverse transcriptase Ank_4 PF13637.6 OQR88804.1 - 2.5e-13 50.3 1.7 0.00081 19.9 0.0 4.5 4 1 0 4 4 4 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 OQR88804.1 - 5.7e-12 45.6 2.6 0.0094 16.3 0.0 5.0 2 2 3 5 5 5 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 OQR88804.1 - 4.9e-11 43.1 0.8 3e-06 27.7 0.1 2.7 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OQR88804.1 - 8.9e-08 31.8 0.6 0.77 10.5 0.0 5.1 4 1 1 5 5 5 2 Ankyrin repeat DUF1843 PF08898.10 OQR88804.1 - 0.027 15.0 0.4 1.5 9.4 0.1 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF1843) DUF3447 PF11929.8 OQR88804.1 - 0.12 12.3 0.0 1.1 9.2 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3447) tRNA-synt_2b PF00587.25 OQR88805.1 - 9.6e-39 133.2 0.0 2e-38 132.1 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 OQR88805.1 - 6.3e-20 71.1 0.9 1.2e-19 70.2 0.9 1.5 1 0 0 1 1 1 1 Anticodon binding domain tRNA_SAD PF07973.14 OQR88805.1 - 5.2e-09 36.1 0.3 1.8e-08 34.3 0.1 2.0 2 0 0 2 2 2 1 Threonyl and Alanyl tRNA synthetase second additional domain Kelch_5 PF13854.6 OQR88806.1 - 7.7e-33 112.0 10.0 1.3e-05 25.0 0.0 7.5 7 0 0 7 7 7 6 Kelch motif Kelch_2 PF07646.15 OQR88806.1 - 7e-30 101.9 17.5 6.5e-05 22.7 0.3 7.3 6 1 0 6 6 6 6 Kelch motif Kelch_3 PF13415.6 OQR88806.1 - 3e-29 100.7 8.0 4.6e-09 36.4 0.0 7.9 8 0 0 8 8 8 4 Galactose oxidase, central domain Kelch_6 PF13964.6 OQR88806.1 - 6e-29 99.4 12.5 0.00048 20.3 0.1 8.5 8 0 0 8 8 8 6 Kelch motif Kelch_1 PF01344.25 OQR88806.1 - 6.6e-27 92.8 9.5 0.0001 21.8 0.0 6.6 6 0 0 6 6 6 6 Kelch motif Kelch_4 PF13418.6 OQR88806.1 - 3.3e-21 75.0 16.5 6.5e-06 26.1 0.3 7.2 7 1 1 8 8 8 6 Galactose oxidase, central domain DUF5071 PF16804.5 OQR88806.1 - 0.036 14.3 2.1 27 5.1 0.0 3.6 2 1 1 3 3 3 0 Domain of unknown function (DUF5071) BTB_2 PF02214.22 OQR88807.1 - 5.7e-12 45.8 0.5 1.7e-11 44.3 0.1 1.9 2 0 0 2 2 2 1 BTB/POZ domain SPRY PF00622.28 OQR88807.1 - 3.2e-05 24.0 0.3 6.1e-05 23.1 0.3 1.4 1 0 0 1 1 1 1 SPRY domain Pkinase PF00069.25 OQR88807.1 - 0.0054 16.1 0.1 0.0076 15.6 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain BTB_3 PF16017.5 OQR88807.1 - 0.08 13.0 0.0 0.16 12.1 0.0 1.5 1 0 0 1 1 1 0 BTB/POZ domain ATP_bind_1 PF03029.17 OQR88810.1 - 1.3e-56 192.1 3.8 8.7e-56 189.4 3.8 1.8 1 1 0 1 1 1 1 Conserved hypothetical ATP binding protein Pkinase PF00069.25 OQR88811.1 - 2.3e-38 132.1 0.0 2.5e-38 132.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQR88811.1 - 3.9e-14 52.6 0.0 4.9e-14 52.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OQR88811.1 - 5.9e-05 22.5 0.0 7.3e-05 22.2 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 OQR88811.1 - 0.041 12.6 0.0 0.063 12.0 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase HTH_Tnp_Tc5 PF03221.16 OQR88811.1 - 0.14 12.2 0.0 0.28 11.2 0.0 1.5 1 0 0 1 1 1 0 Tc5 transposase DNA-binding domain WD40 PF00400.32 OQR88812.1 - 1.5e-10 41.5 9.6 0.0011 19.8 0.1 5.3 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OQR88812.1 - 0.0043 17.3 0.0 3.2 8.1 0.0 3.4 2 1 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain DUF4075 PF13294.6 OQR88812.1 - 0.12 12.5 0.3 0.6 10.3 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4075) Ank_2 PF12796.7 OQR88813.1 - 3.8e-40 136.3 7.2 6.2e-14 52.3 0.2 3.1 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQR88813.1 - 1.7e-33 114.5 2.3 1.3e-10 41.6 0.1 3.9 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 OQR88813.1 - 9.3e-33 111.2 7.4 3.6e-07 30.3 0.0 5.0 5 0 0 5 5 5 5 Ankyrin repeat Ank_3 PF13606.6 OQR88813.1 - 1.6e-24 83.3 0.6 0.00016 21.8 0.0 5.1 5 0 0 5 5 5 5 Ankyrin repeat Ank_5 PF13857.6 OQR88813.1 - 3.9e-24 84.4 11.4 2.2e-07 31.0 0.0 4.8 1 1 4 5 5 5 5 Ankyrin repeats (many copies) PsbR PF04725.12 OQR88813.1 - 0.0046 17.3 0.1 1.7 9.1 0.0 3.0 3 0 0 3 3 3 1 Photosystem II 10 kDa polypeptide PsbR TPR_MLP1_2 PF07926.12 OQR88817.1 - 6.3e-12 45.7 20.0 6.3e-12 45.7 20.0 11.3 4 2 7 13 13 13 3 TPR/MLP1/MLP2-like protein TMF_DNA_bd PF12329.8 OQR88817.1 - 0.0034 17.4 8.1 0.0034 17.4 8.1 13.4 5 3 7 14 14 14 2 TATA element modulatory factor 1 DNA binding MitMem_reg PF13012.6 OQR88825.1 - 6.7e-22 78.0 0.0 1.2e-21 77.2 0.0 1.4 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function JAB PF01398.21 OQR88825.1 - 7.8e-20 71.0 0.0 1.3e-19 70.3 0.0 1.3 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Methyltransf_16 PF10294.9 OQR88826.1 - 1e-22 80.7 0.2 1.7e-22 79.9 0.2 1.3 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_12 PF08242.12 OQR88826.1 - 4.4e-05 24.2 0.2 8.7e-05 23.2 0.2 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 OQR88826.1 - 4.6e-05 23.0 0.3 0.00011 21.8 0.1 1.8 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_25 PF13649.6 OQR88826.1 - 7.5e-05 23.4 0.0 0.00015 22.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 OQR88826.1 - 0.00013 21.5 0.1 0.00027 20.4 0.1 1.5 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) CMAS PF02353.20 OQR88826.1 - 0.00035 19.9 0.0 0.00058 19.2 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_11 PF08241.12 OQR88826.1 - 0.0067 17.1 0.0 0.012 16.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.16 OQR88826.1 - 0.01 15.6 0.0 0.02 14.6 0.0 1.4 1 0 0 1 1 1 0 Met-10+ like-protein Methyltransf_23 PF13489.6 OQR88826.1 - 0.084 12.7 0.0 0.12 12.2 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Kinesin PF00225.23 OQR88827.1 - 2.2e-99 332.6 0.0 2.2e-99 332.6 0.0 2.5 3 0 0 3 3 3 1 Kinesin motor domain Microtub_bd PF16796.5 OQR88827.1 - 2.7e-50 170.2 0.1 9.8e-50 168.4 0.0 2.1 2 0 0 2 2 2 1 Microtubule binding Spc7 PF08317.11 OQR88827.1 - 2.3 7.0 50.9 0.32 9.8 12.7 3.3 1 1 1 3 3 3 0 Spc7 kinetochore protein DUF4201 PF13870.6 OQR88827.1 - 3.3 7.4 38.9 0.057 13.1 11.9 4.3 2 1 2 4 4 4 0 Domain of unknown function (DUF4201) AAA_24 PF13479.6 OQR88827.1 - 5.9 6.6 9.2 3.4 7.3 0.7 3.4 3 1 1 4 4 4 0 AAA domain AMP-binding PF00501.28 OQR88829.1 - 4e-48 164.1 0.0 5e-48 163.7 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 OQR88829.1 - 1.3e-14 54.9 0.1 3.8e-14 53.4 0.1 1.8 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain AAA_33 PF13671.6 OQR88831.1 - 5.5e-22 78.5 0.0 1e-21 77.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 OQR88831.1 - 2.4e-10 40.0 0.0 4.5e-10 39.1 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin KTI12 PF08433.10 OQR88831.1 - 2.8e-06 27.0 0.0 1.7e-05 24.4 0.0 2.1 2 0 0 2 2 2 1 Chromatin associated protein KTI12 AAA_18 PF13238.6 OQR88831.1 - 4.6e-06 27.2 0.0 1.5e-05 25.5 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 OQR88831.1 - 0.00031 21.2 0.0 0.0016 18.9 0.0 2.2 2 1 1 3 3 3 1 AAA ATPase domain CPT PF07931.12 OQR88831.1 - 0.00048 20.0 0.0 0.00081 19.3 0.0 1.3 1 0 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein AAA_22 PF13401.6 OQR88831.1 - 0.00088 19.6 0.0 0.0025 18.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain 6PF2K PF01591.18 OQR88831.1 - 0.0038 16.6 0.0 0.6 9.4 0.0 2.4 2 0 0 2 2 2 1 6-phosphofructo-2-kinase AAA_17 PF13207.6 OQR88831.1 - 0.007 16.8 0.0 0.014 15.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.6 OQR88831.1 - 0.054 13.7 0.0 0.27 11.5 0.0 2.1 2 1 0 2 2 2 0 AAA domain APS_kinase PF01583.20 OQR88831.1 - 0.068 13.1 0.0 0.26 11.2 0.0 1.9 2 0 0 2 2 2 0 Adenylylsulphate kinase DUF2075 PF09848.9 OQR88831.1 - 0.072 12.3 0.0 0.12 11.5 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA PF00004.29 OQR88831.1 - 0.12 12.8 0.0 0.27 11.7 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Glyco_hydro_1 PF00232.18 OQR88832.1 - 7e-31 107.1 0.5 7.4e-31 107.0 0.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 PI3_PI4_kinase PF00454.27 OQR88833.1 - 1.5e-30 106.8 0.1 6.4e-23 81.9 0.1 2.5 1 1 1 2 2 2 2 Phosphatidylinositol 3- and 4-kinase PH PF00169.29 OQR88833.1 - 1.7e-07 31.7 0.7 4e-07 30.5 0.0 2.0 2 0 0 2 2 2 1 PH domain Mcp5_PH PF12814.7 OQR88833.1 - 0.0003 20.9 0.4 0.01 16.0 0.0 2.9 3 0 0 3 3 3 1 Meiotic cell cortex C-terminal pleckstrin homology PH_11 PF15413.6 OQR88833.1 - 0.0023 18.3 0.4 0.037 14.5 0.1 2.8 2 0 0 2 2 2 1 Pleckstrin homology domain Rad52_Rad22 PF04098.15 OQR88834.1 - 8.6e-42 142.7 0.0 1.2e-41 142.2 0.0 1.1 1 0 0 1 1 1 1 Rad52/22 family double-strand break repair protein Med3 PF11593.8 OQR88834.1 - 1.3 8.2 12.9 1.7 7.8 12.9 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal SPX PF03105.19 OQR88834.1 - 1.6 8.6 4.5 2 8.2 4.5 1.1 1 0 0 1 1 1 0 SPX domain Trypsin_2 PF13365.6 OQR88835.1 - 1e-13 52.4 0.0 1.9e-13 51.6 0.0 1.5 1 0 0 1 1 1 1 Trypsin-like peptidase domain DUF3808 PF10300.9 OQR88835.1 - 4.4e-06 25.7 0.7 7.3e-06 25.0 0.7 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3808) TPR_2 PF07719.17 OQR88835.1 - 0.00034 20.5 3.1 9.6 6.6 0.0 4.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 OQR88835.1 - 0.0012 18.8 1.5 0.3 11.4 0.0 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.28 OQR88835.1 - 0.026 14.4 3.8 2.9 7.8 0.0 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat Trypsin PF00089.26 OQR88835.1 - 0.026 14.3 3.6 0.12 12.2 0.2 2.4 2 0 0 2 2 2 0 Trypsin PDZ_6 PF17820.1 OQR88835.1 - 0.038 13.9 0.3 0.54 10.1 0.0 2.6 2 0 0 2 2 2 0 PDZ domain TPR_6 PF13174.6 OQR88835.1 - 0.16 12.7 2.6 18 6.2 0.3 4.0 3 0 0 3 3 3 0 Tetratricopeptide repeat ACT_7 PF13840.6 OQR88836.1 - 1.4e-26 92.1 0.0 1.1e-16 60.3 0.0 2.5 2 0 0 2 2 2 2 ACT domain Castor1_N PF18700.1 OQR88836.1 - 0.052 13.4 0.0 0.13 12.1 0.0 1.6 1 0 0 1 1 1 0 Cytosolic arginine sensor for mTORC1 subunit 1 N-terminal domain ACT PF01842.25 OQR88836.1 - 0.09 12.6 0.0 0.22 11.3 0.0 1.6 1 0 0 1 1 1 0 ACT domain BK_channel_a PF03493.18 OQR88846.1 - 4.6e-17 62.0 1.1 1.4e-15 57.2 0.2 2.7 2 1 0 2 2 2 1 Calcium-activated BK potassium channel alpha subunit TrkA_N PF02254.18 OQR88846.1 - 2.3e-06 27.8 0.1 0.0019 18.5 0.1 2.5 2 0 0 2 2 2 2 TrkA-N domain Amidohydro_1 PF01979.20 OQR88847.1 - 5.4e-20 72.0 0.4 1.2e-18 67.6 0.4 2.2 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 OQR88847.1 - 1.1e-17 64.7 0.9 1.1e-10 41.7 0.0 2.7 1 1 1 2 2 2 2 Amidohydrolase family PAP2 PF01569.21 OQR88851.1 - 2.1e-06 27.5 0.7 1.9e-05 24.4 0.2 2.6 1 1 1 2 2 2 1 PAP2 superfamily DUF212 PF02681.14 OQR88851.1 - 0.033 14.3 2.0 0.069 13.3 0.0 2.3 2 0 0 2 2 2 0 Divergent PAP2 family DUF4238 PF14022.6 OQR88851.1 - 0.064 12.8 1.3 0.11 12.0 1.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4238) FAM76 PF16046.5 OQR88851.1 - 0.61 9.4 8.6 1.1 8.5 8.6 1.4 1 0 0 1 1 1 0 FAM76 protein KIAA1430 PF13879.6 OQR88851.1 - 2.5 8.9 11.1 23 5.8 0.4 2.9 2 0 0 2 2 2 0 KIAA1430 homologue Elicitin PF00964.17 OQR88853.1 - 0.00068 19.7 0.1 0.07 13.2 0.1 2.4 2 0 0 2 2 2 2 Elicitin Elicitin PF00964.17 OQR88854.1 - 0.036 14.2 0.1 0.051 13.7 0.1 1.2 1 0 0 1 1 1 0 Elicitin C2 PF00168.30 OQR88862.1 - 6.2e-20 71.4 0.0 1.1e-19 70.6 0.0 1.4 1 0 0 1 1 1 1 C2 domain Pex24p PF06398.11 OQR88862.1 - 0.0032 16.5 0.4 0.0046 16.0 0.4 1.2 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin Pkinase_Tyr PF07714.17 OQR88863.1 - 9.6e-27 93.9 0.0 1.4e-26 93.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OQR88863.1 - 3.3e-25 88.9 0.0 4.7e-25 88.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain S_4TM PF18159.1 OQR88863.1 - 3.5 6.8 8.5 1.8 7.8 0.0 2.9 2 1 1 3 3 3 0 SMODS-associating 4TM effector domain Aa_trans PF01490.18 OQR88864.1 - 1.6e-39 135.8 29.3 2.2e-39 135.3 29.3 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DUF3959 PF13105.6 OQR88864.1 - 0.15 11.6 6.3 0.034 13.7 2.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3959) UPF0182 PF03699.13 OQR88864.1 - 0.28 9.3 6.0 0.54 8.3 6.0 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0182) WD40 PF00400.32 OQR88865.1 - 1e-20 73.7 3.0 4e-05 24.3 0.1 9.3 9 0 0 9 9 9 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OQR88865.1 - 3.7e-05 24.0 0.0 0.87 9.9 0.0 4.5 3 1 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain DDE_1 PF03184.19 OQR88866.1 - 0.19 11.3 0.0 0.28 10.8 0.0 1.2 1 0 0 1 1 1 0 DDE superfamily endonuclease EamA PF00892.20 OQR88867.1 - 8.3e-28 97.3 69.6 2.6e-14 53.6 16.7 4.1 3 1 1 4 4 4 3 EamA-like transporter family TPT PF03151.16 OQR88867.1 - 6.2e-05 22.5 23.5 0.0024 17.3 1.9 3.5 1 1 2 3 3 3 2 Triose-phosphate Transporter family Nuc_sug_transp PF04142.15 OQR88867.1 - 0.00011 21.5 14.5 0.0054 16.0 1.9 3.1 2 2 0 3 3 3 2 Nucleotide-sugar transporter FemAB PF02388.16 OQR88868.1 - 0.003 16.5 2.2 0.003 16.5 2.2 1.9 1 1 1 2 2 2 1 FemAB family HrpB7 PF09486.10 OQR88868.1 - 0.004 17.6 9.2 0.65 10.4 0.1 2.2 2 0 0 2 2 2 2 Bacterial type III secretion protein (HrpB7) AAA_13 PF13166.6 OQR88868.1 - 0.06 12.0 12.1 0.11 11.2 12.1 1.4 1 1 0 1 1 1 0 AAA domain Fez1 PF06818.15 OQR88868.1 - 0.26 11.7 17.2 0.48 10.8 9.2 2.0 2 0 0 2 2 2 0 Fez1 CCDC23 PF15674.5 OQR88868.1 - 0.4 10.7 6.8 15 5.6 0.0 2.9 2 1 0 2 2 2 0 Coiled-coil domain-containing protein 23 Spc7 PF08317.11 OQR88868.1 - 0.5 9.2 15.2 5.1 5.9 0.1 2.1 2 0 0 2 2 2 0 Spc7 kinetochore protein DUF724 PF05266.14 OQR88868.1 - 1.8 8.4 12.2 2.6 7.8 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF724) Bcr-Abl_Oligo PF09036.10 OQR88868.1 - 2.1 8.4 10.8 0.46 10.5 1.7 2.9 2 1 1 3 3 3 0 Bcr-Abl oncoprotein oligomerisation domain DUF1664 PF07889.12 OQR88868.1 - 3.1 7.9 10.9 14 5.7 6.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) DUF3450 PF11932.8 OQR88868.1 - 5.8 6.1 9.8 13 5.0 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) DASH_Dam1 PF08653.10 OQR88871.1 - 6.9e-08 32.2 0.0 1.6e-07 31.0 0.0 1.6 1 0 0 1 1 1 1 DASH complex subunit Dam1 Cpn60_TCP1 PF00118.24 OQR88872.1 - 1.9e-43 148.9 0.0 1e-42 146.4 0.0 1.9 1 1 1 2 2 2 1 TCP-1/cpn60 chaperonin family NTP_transf_2 PF01909.23 OQR88873.1 - 1.6e-07 31.5 0.1 1.5e-06 28.4 0.0 2.3 2 0 0 2 2 2 1 Nucleotidyltransferase domain PAP_assoc PF03828.19 OQR88873.1 - 1.3e-05 25.3 0.2 1.3e-05 25.3 0.2 3.1 3 1 0 3 3 2 1 Cid1 family poly A polymerase VasL PF12486.8 OQR88873.1 - 0.013 15.4 1.4 0.013 15.4 1.4 1.9 2 0 0 2 2 2 0 Type VI secretion system, EvfB, or VasL ATG16 PF08614.11 OQR88873.1 - 0.015 15.5 1.0 0.015 15.5 1.0 2.4 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) BLOC1_2 PF10046.9 OQR88873.1 - 0.06 13.6 2.2 0.13 12.6 1.5 1.9 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Uds1 PF15456.6 OQR88873.1 - 0.073 13.2 0.1 0.073 13.2 0.1 2.5 2 0 0 2 2 2 0 Up-regulated During Septation AAA_32 PF13654.6 OQR88873.1 - 0.26 10.0 10.2 0.55 8.9 2.4 2.1 2 0 0 2 2 2 0 AAA domain DUF812 PF05667.11 OQR88873.1 - 1.2 7.9 13.9 5.8 5.7 13.9 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF812) ZapB PF06005.12 OQR88873.1 - 1.4 9.4 12.2 0.085 13.3 4.5 2.5 2 0 0 2 2 2 0 Cell division protein ZapB SlyX PF04102.12 OQR88873.1 - 2.4 8.8 5.1 1.1 9.9 1.0 2.6 2 1 1 3 3 3 0 SlyX UPF0242 PF06785.11 OQR88873.1 - 5.1 7.2 8.9 0.18 11.9 0.3 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Ras PF00071.22 OQR88877.1 - 1.9e-18 66.6 0.0 2.9e-18 66.0 0.0 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OQR88877.1 - 5.1e-14 52.5 0.0 8.9e-14 51.7 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OQR88877.1 - 0.0044 16.5 0.0 0.0072 15.8 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Pex16 PF08610.10 OQR88881.1 - 0.031 13.4 0.0 0.039 13.1 0.0 1.2 1 0 0 1 1 1 0 Peroxisomal membrane protein (Pex16) InPase PF18823.1 OQR88881.1 - 0.12 12.1 0.2 0.18 11.5 0.2 1.2 1 0 0 1 1 1 0 Inorganic Pyrophosphatase PT PF04886.12 OQR88882.1 - 1.3e-12 47.0 93.9 1.7e-07 30.6 24.6 6.6 4 2 2 6 6 6 4 PT repeat CAP PF00188.26 OQR88882.1 - 1.5e-09 38.7 0.3 5.1e-09 37.0 0.3 1.9 1 0 0 1 1 1 1 Cysteine-rich secretory protein family Ank_5 PF13857.6 OQR88883.1 - 0.0012 19.1 0.5 0.037 14.4 0.1 2.0 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 OQR88883.1 - 0.048 14.2 0.6 0.92 10.2 0.4 2.0 1 1 1 2 2 2 0 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQR88883.1 - 0.053 14.1 0.3 3 8.7 0.1 2.5 2 1 1 3 3 3 0 Ankyrin repeat Ank_2 PF12796.7 OQR88883.1 - 0.058 14.0 0.2 0.09 13.4 0.2 1.4 1 1 0 1 1 1 0 Ankyrin repeats (3 copies) Ank_2 PF12796.7 OQR88884.1 - 1.8e-23 82.9 9.3 2.6e-08 34.3 0.6 4.2 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQR88884.1 - 1.4e-21 76.5 10.0 7.8e-05 23.2 0.1 5.6 4 2 2 6 6 6 6 Ankyrin repeats (many copies) Ank_5 PF13857.6 OQR88884.1 - 2.5e-16 59.5 12.0 0.14 12.5 0.1 7.9 1 1 7 8 8 8 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQR88884.1 - 3.9e-12 45.2 3.0 0.73 10.6 0.0 7.5 6 2 2 8 8 8 3 Ankyrin repeat Ank PF00023.30 OQR88884.1 - 1.4e-10 41.1 2.2 1.2 9.7 0.1 7.6 4 2 2 6 6 6 3 Ankyrin repeat DUF5049 PF16468.5 OQR88884.1 - 0.00015 21.6 4.0 8.7 6.3 0.0 5.6 4 2 3 7 7 7 1 Domain of unknown function (DUF5049) DUF1707 PF08044.11 OQR88884.1 - 0.0012 18.8 1.0 5 7.3 0.0 4.6 6 0 0 6 6 6 1 Domain of unknown function (DUF1707) Sushi_2 PF09014.10 OQR88884.1 - 0.026 14.4 1.5 15 5.6 0.0 3.4 2 1 1 4 4 4 0 Beta-2-glycoprotein-1 fifth domain DsrC PF04358.13 OQR88884.1 - 0.064 13.8 0.1 3.1 8.4 0.0 3.2 2 1 0 2 2 2 0 DsrC like protein EF-hand_7 PF13499.6 OQR88885.1 - 1.5e-10 41.3 1.4 8.3e-05 23.0 0.6 5.0 5 0 0 5 5 5 2 EF-hand domain pair EF-hand_6 PF13405.6 OQR88885.1 - 8.2e-07 28.5 3.2 0.028 14.3 0.7 4.1 3 0 0 3 3 3 2 EF-hand domain EF-hand_8 PF13833.6 OQR88885.1 - 0.00014 21.6 0.3 0.44 10.4 0.0 4.0 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_1 PF00036.32 OQR88885.1 - 0.0024 17.3 3.7 1.6 8.5 0.3 3.8 3 0 0 3 3 3 2 EF hand MCD_N PF17408.2 OQR88885.1 - 0.1 12.7 0.1 0.63 10.2 0.0 2.3 2 0 0 2 2 2 0 Malonyl-CoA decarboxylase N-terminal domain Ank_5 PF13857.6 OQR88886.1 - 1.4e-13 50.8 0.3 0.0012 19.1 0.2 3.3 1 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 OQR88886.1 - 2.3e-11 44.0 1.8 0.002 18.7 0.0 3.1 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 OQR88886.1 - 1.2e-07 32.2 0.8 0.0031 18.1 0.0 2.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OQR88886.1 - 0.00012 22.3 0.1 8.9 7.3 0.0 3.8 3 1 1 4 4 4 2 Ankyrin repeat DUF5049 PF16468.5 OQR88886.1 - 0.0057 16.5 0.0 6.5 6.7 0.1 3.0 2 1 1 3 3 3 1 Domain of unknown function (DUF5049) S1FA PF04689.13 OQR88887.1 - 0.11 12.7 0.1 0.22 11.7 0.1 1.5 1 0 0 1 1 1 0 DNA binding protein S1FA Aminotran_1_2 PF00155.21 OQR88891.1 - 4.5e-44 151.1 0.0 5.6e-44 150.8 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II KLRAQ PF10205.9 OQR88892.1 - 0.00038 20.6 3.2 0.00038 20.6 3.2 4.7 4 2 3 7 7 7 1 Predicted coiled-coil domain-containing protein DASH_Hsk3 PF08227.11 OQR88893.1 - 0.027 14.9 1.7 0.045 14.1 1.7 1.5 1 1 0 1 1 1 0 DASH complex subunit Hsk3 like Pro_isomerase PF00160.21 OQR88894.1 - 4.1e-40 137.6 0.2 6.1e-40 137.1 0.2 1.2 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Pkinase PF00069.25 OQR88898.1 - 1.8e-44 152.1 0.0 3.3e-44 151.2 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQR88898.1 - 1.9e-44 151.9 0.0 3.3e-44 151.1 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase LRR_8 PF13855.6 OQR88898.1 - 1.7e-13 50.1 31.2 2.2e-07 30.5 6.3 4.8 3 1 4 7 7 7 4 Leucine rich repeat LRR_4 PF12799.7 OQR88898.1 - 7.1e-08 32.6 33.1 0.0001 22.6 2.8 5.7 1 1 6 7 7 7 5 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 OQR88898.1 - 2.2e-07 30.5 7.2 0.0016 18.0 2.2 2.5 1 1 1 2 2 2 2 Leucine-rich repeat Pkinase_fungal PF17667.1 OQR88898.1 - 1.2e-05 24.3 0.0 1.9e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 OQR88898.1 - 0.011 15.1 0.0 0.024 14.0 0.0 1.5 2 0 0 2 2 2 0 Kinase-like TBPIP PF07106.13 OQR88899.1 - 5.2e-22 77.5 0.6 5.2e-22 77.5 0.6 2.2 2 0 0 2 2 2 1 TBPIP/Hop2 winged helix domain LZ3wCH PF18517.1 OQR88899.1 - 1.9e-09 37.5 0.1 1e-08 35.1 0.1 2.4 1 0 0 1 1 1 1 Leucine zipper with capping helix domain Penicillinase_R PF03965.16 OQR88899.1 - 0.0011 19.3 3.0 0.0033 17.8 0.2 2.5 2 1 0 2 2 2 1 Penicillinase repressor RPW8 PF05659.11 OQR88899.1 - 0.044 13.5 1.7 0.073 12.8 0.2 2.1 2 1 0 2 2 2 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 MID_MedPIWI PF18296.1 OQR88899.1 - 0.049 13.4 4.6 1.3 8.8 2.3 2.1 2 0 0 2 2 2 0 MID domain of medPIWI GCR1_C PF12550.8 OQR88899.1 - 0.051 13.9 0.2 2.1 8.7 0.0 2.5 2 0 0 2 2 2 0 Transcriptional activator of glycolytic enzymes DUF5427 PF10310.9 OQR88899.1 - 0.088 11.7 13.9 0.19 10.6 10.9 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF5427) SlyX PF04102.12 OQR88899.1 - 0.65 10.6 5.2 41 4.9 5.2 2.8 1 1 0 1 1 1 0 SlyX Presenilin PF01080.17 OQR88899.1 - 1 8.1 4.5 1.1 7.9 4.5 1.2 1 0 0 1 1 1 0 Presenilin COG2 PF06148.11 OQR88899.1 - 1 9.4 4.3 0.29 11.2 0.6 1.9 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 CDC45 PF02724.14 OQR88899.1 - 1.1 7.5 9.0 1.5 7.0 9.0 1.3 1 0 0 1 1 1 0 CDC45-like protein SKA1 PF07160.12 OQR88899.1 - 1.2 9.0 13.5 0.54 10.1 0.2 2.3 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 1 PTPRCAP PF15713.5 OQR88899.1 - 3.9 7.8 9.1 8.4 6.7 9.1 1.5 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated eIF3_subunit PF08597.10 OQR88899.1 - 5.6 6.8 24.9 0.66 9.8 20.2 1.7 2 0 0 2 2 2 0 Translation initiation factor eIF3 subunit PUF PF00806.19 OQR88901.1 - 1.3e-61 200.9 9.9 7.6e-08 31.6 0.0 8.4 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat sCache_2 PF17200.4 OQR88901.1 - 0.076 12.9 0.1 52 3.6 0.0 4.0 5 0 0 5 5 5 0 Single Cache domain 2 UPF0259 PF06790.11 OQR88901.1 - 0.22 11.3 0.3 0.33 10.7 0.3 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0259) Pro_CA PF00484.19 OQR88902.1 - 1.1e-49 168.7 0.1 1.8e-49 168.1 0.1 1.3 1 0 0 1 1 1 1 Carbonic anhydrase Ricin_B_lectin PF00652.22 OQR88910.1 - 1.1e-20 74.2 26.0 2.3e-12 47.3 4.9 3.3 3 0 0 3 3 3 2 Ricin-type beta-trefoil lectin domain Trypsin_2 PF13365.6 OQR88910.1 - 1.9e-14 54.8 0.4 4.6e-14 53.6 0.4 1.7 1 0 0 1 1 1 1 Trypsin-like peptidase domain RicinB_lectin_2 PF14200.6 OQR88910.1 - 4e-05 24.2 25.5 0.035 14.8 1.8 5.1 2 1 3 5 5 5 3 Ricin-type beta-trefoil lectin domain-like Peptidase_S46 PF10459.9 OQR88910.1 - 0.025 13.2 1.7 0.25 9.9 0.1 2.1 2 0 0 2 2 2 0 Peptidase S46 DEC-1_N PF04625.13 OQR88910.1 - 0.97 8.4 2.6 1.6 7.7 2.6 1.2 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region YopE_N PF09020.10 OQR88910.1 - 8 6.7 8.0 11 6.3 0.6 3.5 4 0 0 4 4 4 0 YopE, N terminal Alg6_Alg8 PF03155.15 OQR88914.1 - 2.8e-55 188.2 18.6 3.6e-55 187.8 18.6 1.1 1 0 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family SDF PF00375.18 OQR88915.1 - 9.9e-27 94.0 12.7 3.9e-26 92.0 12.7 1.8 1 1 0 1 1 1 1 Sodium:dicarboxylate symporter family DUF4501 PF14946.6 OQR88915.1 - 0.0019 18.3 0.2 0.037 14.1 0.0 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF4501) p450 PF00067.22 OQR88917.1 - 2.6e-58 197.9 0.0 3e-58 197.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Pkinase_Tyr PF07714.17 OQR88920.1 - 3e-44 151.3 0.0 3.9e-44 150.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OQR88920.1 - 6.4e-44 150.3 0.0 8.9e-44 149.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Ank_5 PF13857.6 OQR88920.1 - 4.2e-22 77.9 5.7 8.8e-12 45.0 0.2 4.0 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 OQR88920.1 - 2e-20 73.1 0.6 1.4e-15 57.6 0.5 2.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQR88920.1 - 5e-17 62.0 0.7 8.3e-07 29.4 0.1 3.4 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 OQR88920.1 - 1.9e-14 53.4 7.1 1.8e-05 25.0 0.4 4.6 4 0 0 4 4 4 3 Ankyrin repeat Ank_3 PF13606.6 OQR88920.1 - 1.2e-12 46.8 2.7 0.0001 22.4 0.1 4.1 4 0 0 4 4 4 3 Ankyrin repeat Pkinase_fungal PF17667.1 OQR88920.1 - 0.00013 20.9 0.0 0.00018 20.4 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase FMN_bind_2 PF04299.12 OQR88921.1 - 5.6e-49 166.1 0.2 6.8e-49 165.8 0.2 1.1 1 0 0 1 1 1 1 Putative FMN-binding domain Pyridox_ox_2 PF12900.7 OQR88921.1 - 0.1 12.6 0.0 0.15 12.0 0.0 1.4 1 1 0 1 1 1 0 Pyridoxamine 5'-phosphate oxidase Sugar_tr PF00083.24 OQR88922.1 - 9.8e-43 146.6 31.4 1.1e-26 93.8 2.6 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 OQR88922.1 - 8e-27 94.1 32.7 1.7e-18 66.7 8.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily AbiJ_NTD5 PF18865.1 OQR88922.1 - 0.1 12.4 0.0 0.2 11.5 0.0 1.4 1 0 0 1 1 1 0 AbiJ N-terminal domain 5 SET PF00856.28 OQR88923.1 - 0.00027 21.4 0.0 0.12 12.8 0.0 2.3 2 0 0 2 2 2 2 SET domain PRCH PF03967.13 OQR88923.1 - 0.058 13.6 0.0 0.59 10.4 0.0 2.6 1 1 1 3 3 3 0 Photosynthetic reaction centre, H-chain N-terminal region F-actin_cap_A PF01267.17 OQR88924.1 - 3.4e-69 233.3 0.4 4e-69 233.0 0.4 1.1 1 0 0 1 1 1 1 F-actin capping protein alpha subunit AMP-binding PF00501.28 OQR88926.1 - 1.8e-37 128.9 0.2 2.5e-37 128.5 0.2 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 OQR88926.1 - 0.00012 23.0 0.0 0.00025 22.0 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Hexapep_2 PF14602.6 OQR88926.1 - 0.0004 20.1 8.2 0.26 11.1 0.2 5.1 5 0 0 5 5 5 2 Hexapeptide repeat of succinyl-transferase Hexapep PF00132.24 OQR88926.1 - 0.0019 17.8 10.5 0.6 9.9 0.1 5.9 9 0 0 9 9 9 2 Bacterial transferase hexapeptide (six repeats) FAE1_CUT1_RppA PF08392.12 OQR88926.1 - 0.022 14.0 0.0 0.05 12.9 0.0 1.5 1 0 0 1 1 1 0 FAE1/Type III polyketide synthase-like protein Myosin_head PF00063.21 OQR88927.1 - 1.1e-159 532.8 13.7 1.3e-116 390.4 1.0 2.8 3 0 0 3 3 3 2 Myosin head (motor domain) Zeta_toxin PF06414.12 OQR88927.1 - 0.019 14.2 0.0 0.05 12.9 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin FlaC_arch PF05377.11 OQR88927.1 - 0.023 15.1 2.5 0.8 10.1 0.1 3.8 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) TPR_5 PF12688.7 OQR88927.1 - 0.062 13.5 0.5 0.33 11.2 0.1 2.4 2 0 0 2 2 1 0 Tetratrico peptide repeat ADIP PF11559.8 OQR88927.1 - 0.087 12.9 27.4 0.031 14.3 6.5 3.8 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding AAA_22 PF13401.6 OQR88927.1 - 0.17 12.2 2.6 0.28 11.5 0.0 2.8 3 0 0 3 3 2 0 AAA domain ABC_tran PF00005.27 OQR88927.1 - 0.52 10.8 0.0 0.52 10.8 0.0 3.5 3 1 0 3 3 2 0 ABC transporter AAA_16 PF13191.6 OQR88927.1 - 0.9 9.9 0.0 0.9 9.9 0.0 3.3 3 1 0 3 3 3 0 AAA ATPase domain Csm1_N PF18504.1 OQR88927.1 - 1.1 9.7 20.3 4.6 7.6 0.3 4.9 2 1 2 4 4 4 0 Csm1 N-terminal domain PKcGMP_CC PF16808.5 OQR88927.1 - 1.1 9.2 7.1 27 4.7 0.4 4.0 2 1 2 4 4 4 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Spc7 PF08317.11 OQR88927.1 - 1.2 7.9 27.8 3.3 6.5 11.9 2.6 1 1 1 2 2 2 0 Spc7 kinetochore protein GAS PF13851.6 OQR88927.1 - 1.4 8.2 31.6 0.43 9.9 14.1 3.7 2 1 1 3 3 3 0 Growth-arrest specific micro-tubule binding IQ PF00612.27 OQR88927.1 - 1.4 8.9 13.4 0.39 10.6 0.6 3.6 3 0 0 3 3 3 0 IQ calmodulin-binding motif SlyX PF04102.12 OQR88927.1 - 1.7 9.3 22.0 0.61 10.7 4.0 5.2 2 1 2 4 4 3 0 SlyX Fib_alpha PF08702.10 OQR88927.1 - 1.7 8.8 10.7 0.27 11.4 4.3 2.7 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Baculo_PEP_C PF04513.12 OQR88927.1 - 5.5 7.0 17.5 1.3 9.1 9.7 2.7 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus UPF0242 PF06785.11 OQR88927.1 - 6.8 6.8 25.4 5.5 7.0 11.1 2.6 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus FlxA PF14282.6 OQR88927.1 - 7.2 6.7 17.7 0.4 10.7 1.8 3.7 2 1 1 3 3 3 0 FlxA-like protein CdvA PF18822.1 OQR88927.1 - 9.9 6.0 17.2 5.1 7.0 1.1 4.2 3 1 1 4 4 4 0 CdvA-like coiled-coil domain Myosin_head PF00063.21 OQR88928.1 - 2.6e-135 452.3 0.1 2.5e-117 392.8 0.0 2.1 2 0 0 2 2 2 2 Myosin head (motor domain) AAA_22 PF13401.6 OQR88928.1 - 0.0075 16.5 0.0 0.025 14.8 0.0 2.0 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 OQR88928.1 - 0.015 14.6 0.0 0.027 13.7 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin T2SSE PF00437.20 OQR88928.1 - 0.015 14.4 0.0 0.026 13.6 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_16 PF13191.6 OQR88928.1 - 0.045 14.1 0.0 0.14 12.5 0.0 1.8 1 0 0 1 1 1 0 AAA ATPase domain ABC_tran PF00005.27 OQR88928.1 - 0.068 13.7 0.1 0.22 12.0 0.0 1.9 2 0 0 2 2 2 0 ABC transporter IQ PF00612.27 OQR88930.1 - 1e-07 31.1 10.4 0.0049 16.5 0.5 4.0 3 0 0 3 3 3 2 IQ calmodulin-binding motif EF-hand_5 PF13202.6 OQR88930.1 - 0.00056 19.3 0.0 0.002 17.6 0.0 1.9 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.6 OQR88930.1 - 0.0018 18.7 0.1 0.16 12.5 0.0 3.2 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_6 PF13405.6 OQR88930.1 - 0.0038 17.0 0.0 0.039 13.9 0.0 2.7 3 0 0 3 3 3 1 EF-hand domain FPP PF05911.11 OQR88930.1 - 0.015 13.5 12.4 0.025 12.8 12.4 1.3 1 0 0 1 1 1 0 Filament-like plant protein, long coiled-coil EF-hand_1 PF00036.32 OQR88930.1 - 0.034 13.7 0.0 0.086 12.4 0.0 1.8 1 0 0 1 1 1 0 EF hand EF-hand_9 PF14658.6 OQR88930.1 - 0.045 14.1 0.0 0.27 11.6 0.0 2.3 2 0 0 2 2 2 0 EF-hand domain DUF190 PF02641.15 OQR88930.1 - 0.059 13.7 0.2 0.15 12.4 0.2 1.6 1 0 0 1 1 1 0 Uncharacterized ACR, COG1993 SPG48 PF14764.6 OQR88930.1 - 0.095 13.2 2.5 0.35 11.4 0.1 3.0 3 0 0 3 3 3 0 AP-5 complex subunit, vesicle trafficking MscS_porin PF12795.7 OQR88930.1 - 0.13 11.8 6.3 0.28 10.7 6.3 1.5 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain Tup_N PF08581.10 OQR88930.1 - 0.18 12.1 3.7 0.26 11.6 1.7 2.3 1 1 0 1 1 1 0 Tup N-terminal Snapin_Pallidin PF14712.6 OQR88930.1 - 0.21 12.0 4.1 9.6 6.7 1.2 3.0 2 0 0 2 2 2 0 Snapin/Pallidin Serine_rich PF08824.10 OQR88930.1 - 0.39 10.7 4.5 0.79 9.7 2.1 2.7 1 1 0 2 2 2 0 Serine rich protein interaction domain LMBR1 PF04791.16 OQR88930.1 - 0.96 8.3 5.6 1.6 7.6 5.6 1.4 1 0 0 1 1 1 0 LMBR1-like membrane protein Syntaxin_2 PF14523.6 OQR88930.1 - 1.3 9.4 12.2 1.1 9.7 9.2 2.5 2 0 0 2 2 2 0 Syntaxin-like protein Allexi_40kDa PF05549.11 OQR88930.1 - 5 6.6 10.9 0.95 8.9 4.8 2.5 1 1 0 2 2 2 0 Allexivirus 40kDa protein RSN1_7TM PF02714.15 OQR88931.1 - 8.8e-30 103.9 26.0 8.8e-30 103.9 26.0 2.2 3 0 0 3 3 3 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 OQR88931.1 - 2.1e-17 63.3 3.5 2.1e-17 63.3 3.5 3.0 4 1 0 4 4 4 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 OQR88931.1 - 5.4e-07 30.0 0.0 2.3e-06 28.0 0.0 2.2 1 1 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter HTH_ABP1_N PF18107.1 OQR88931.1 - 0.00031 20.4 0.1 0.0078 15.9 0.0 2.8 2 0 0 2 2 2 1 Fission yeast centromere protein N-terminal domain DUF4267 PF14087.6 OQR88931.1 - 0.17 12.0 2.0 3.1 7.9 0.0 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4267) RabGAP-TBC PF00566.18 OQR88932.1 - 4.1e-30 105.0 0.0 6.9e-30 104.3 0.0 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain DUF1772 PF08592.11 OQR88936.1 - 0.8 10.0 5.4 1.9 8.8 0.1 3.2 2 2 1 3 3 3 0 Domain of unknown function (DUF1772) TPR_1 PF00515.28 OQR88937.1 - 2.5e-16 58.7 0.6 0.0017 18.1 0.2 4.6 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_12 PF13424.6 OQR88937.1 - 4.6e-15 55.7 6.9 2.1e-06 27.9 0.3 4.6 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.17 OQR88937.1 - 3e-14 51.9 0.6 0.0084 16.2 0.1 5.4 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_10 PF13374.6 OQR88937.1 - 1.3e-12 47.2 4.0 6.7e-05 22.6 0.3 4.7 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_7 PF13176.6 OQR88937.1 - 2.2e-10 39.8 1.2 0.0018 18.2 0.1 4.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 OQR88937.1 - 9.5e-10 37.9 1.9 0.04 14.1 0.0 4.9 5 0 0 5 5 5 2 Tetratricopeptide repeat SNAP PF14938.6 OQR88937.1 - 0.0042 16.6 0.0 0.0081 15.6 0.0 1.5 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_11 PF13414.6 OQR88937.1 - 0.009 15.7 1.0 2.2 8.1 0.0 4.2 4 1 0 4 4 4 1 TPR repeat RPN7 PF10602.9 OQR88937.1 - 0.017 14.9 1.0 1.4 8.6 0.1 2.7 1 1 1 2 2 2 0 26S proteasome subunit RPN7 Gp_dh_N PF00044.24 OQR88937.1 - 0.034 14.5 0.0 0.092 13.1 0.0 1.7 1 0 0 1 1 1 0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain TPR_MalT PF17874.1 OQR88937.1 - 0.23 10.8 5.5 1.4e+02 1.6 0.0 3.0 1 1 0 2 2 2 0 MalT-like TPR region Ank_2 PF12796.7 OQR88938.1 - 8.6e-15 55.1 5.6 2.1e-05 25.0 0.1 3.1 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQR88938.1 - 2.1e-11 44.1 2.7 0.0053 17.3 0.1 4.7 1 1 5 6 6 6 6 Ankyrin repeats (many copies) Ank_5 PF13857.6 OQR88938.1 - 2.2e-10 40.6 3.4 0.22 11.9 0.0 6.0 3 1 3 6 6 6 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQR88938.1 - 4.6e-09 35.8 1.1 0.31 11.7 0.0 5.6 5 1 1 6 6 6 2 Ankyrin repeat DUF3447 PF11929.8 OQR88938.1 - 0.0016 18.4 0.1 0.69 9.9 0.0 3.4 1 1 2 3 3 3 2 Domain of unknown function (DUF3447) Ank PF00023.30 OQR88938.1 - 0.02 15.3 0.3 3.1 8.4 0.1 3.7 3 2 0 3 3 3 0 Ankyrin repeat DUF5049 PF16468.5 OQR88938.1 - 0.075 12.9 0.2 3.2 7.7 0.0 3.2 3 1 1 4 4 4 0 Domain of unknown function (DUF5049) VWA_3_C PF18571.1 OQR88938.1 - 0.15 11.9 0.0 5 7.1 0.0 3.0 3 0 0 3 3 3 0 von Willebrand factor type A C-terminal domain DNA_pol_A_exo1 PF01612.20 OQR88939.1 - 1.9e-15 57.0 0.0 3.7e-15 56.1 0.0 1.4 1 0 0 1 1 1 1 3'-5' exonuclease Ank_2 PF12796.7 OQR88940.1 - 1.2e-80 266.1 32.1 9.7e-16 58.1 0.0 9.2 5 2 5 10 10 9 8 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQR88940.1 - 2.1e-60 200.4 21.6 1e-09 38.7 0.0 13.6 5 3 8 13 13 13 12 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQR88940.1 - 4.6e-55 177.1 24.3 2.2e-05 24.5 0.0 17.4 18 0 0 18 18 18 12 Ankyrin repeat Ank_5 PF13857.6 OQR88940.1 - 8.4e-51 169.4 21.9 1.1e-11 44.7 0.0 11.6 7 4 4 12 12 12 9 Ankyrin repeats (many copies) Pkinase PF00069.25 OQR88940.1 - 6.7e-44 150.2 0.0 1.8e-43 148.8 0.0 1.7 1 0 0 1 1 1 1 Protein kinase domain Ank PF00023.30 OQR88940.1 - 4.4e-43 143.9 36.8 3.5e-06 27.2 0.0 15.8 16 0 0 16 16 15 10 Ankyrin repeat Pkinase_Tyr PF07714.17 OQR88940.1 - 6e-41 140.4 0.1 5.8e-39 133.9 0.0 2.5 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 OQR88940.1 - 0.063 12.6 0.0 0.12 11.6 0.0 1.4 1 0 0 1 1 1 0 Kinase-like TackOD1 PF18551.1 OQR88940.1 - 1.2 8.8 8.0 0.92 9.1 2.0 3.1 2 1 1 3 3 3 0 Thaumarchaeal output domain 1 zf-C4pol PF14260.6 OQR88940.1 - 2.5 8.6 8.1 8.2 7.0 8.1 1.9 1 0 0 1 1 1 0 C4-type zinc-finger of DNA polymerase delta Vps36-NZF-N PF16988.5 OQR88940.1 - 6.6 6.2 8.3 2 7.9 1.0 2.8 2 0 0 2 2 2 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain DZR PF12773.7 OQR88940.1 - 8.6 6.5 7.0 62 3.7 2.8 2.4 1 1 2 3 3 3 0 Double zinc ribbon NUDIX PF00293.28 OQR88942.1 - 1.6e-16 60.6 0.1 3.1e-16 59.6 0.1 1.4 1 0 0 1 1 1 1 NUDIX domain zf-Di19 PF05605.12 OQR88942.1 - 9.6e-09 35.4 5.9 1.9e-08 34.4 5.9 1.6 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding zinc_ribbon_9 PF14369.6 OQR88942.1 - 0.056 13.7 3.0 10 6.5 0.7 2.8 2 0 0 2 2 2 0 zinc-ribbon Ribosomal_L37ae PF01780.19 OQR88942.1 - 0.12 12.4 0.2 0.64 10.2 0.0 2.2 3 0 0 3 3 3 0 Ribosomal L37ae protein family zf-H2C2_2 PF13465.6 OQR88942.1 - 4.8 7.8 6.7 2.4 8.8 0.1 3.0 3 0 0 3 3 3 0 Zinc-finger double domain Rtf2 PF04641.12 OQR88943.1 - 5.3e-14 52.2 1.6 1.3e-13 50.9 1.6 1.6 1 1 0 1 1 1 1 Rtf2 RING-finger zf-NOSIP PF15906.5 OQR88943.1 - 7e-07 29.3 0.3 2.1e-06 27.7 0.1 2.0 2 0 0 2 2 2 1 Zinc-finger of nitric oxide synthase-interacting protein zf-Nse PF11789.8 OQR88943.1 - 3.4e-05 23.6 0.3 0.00077 19.2 0.2 2.4 2 0 0 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit Pro_isomerase PF00160.21 OQR88943.1 - 0.00086 19.6 0.0 0.0029 17.9 0.0 2.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD U-box PF04564.15 OQR88943.1 - 0.0067 16.6 0.0 0.19 11.9 0.0 2.5 2 0 0 2 2 2 1 U-box domain DUF4706 PF15797.5 OQR88943.1 - 0.016 15.8 0.1 0.082 13.4 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4706) EF-hand_like PF09279.11 OQR88943.1 - 0.56 10.7 4.1 1.2 9.6 0.2 3.2 2 2 0 2 2 2 0 Phosphoinositide-specific phospholipase C, efhand-like DUF3774 PF12609.8 OQR88943.1 - 4.3 8.4 5.2 48 5.1 0.0 3.0 3 0 0 3 3 3 0 Wound-induced protein KOW PF00467.29 OQR88944.1 - 0.0086 16.0 0.1 9.9 6.3 0.1 3.8 4 0 0 4 4 4 2 KOW motif EF-hand_1 PF00036.32 OQR88945.1 - 2.3e-18 64.3 8.8 8.9e-06 24.9 1.7 4.4 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.6 OQR88945.1 - 3.3e-15 54.6 9.8 7.8e-05 22.3 1.3 4.4 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 OQR88945.1 - 9.5e-15 54.2 5.4 8.2e-06 25.6 0.4 4.3 4 0 0 4 4 4 4 EF-hand domain pair EF-hand_7 PF13499.6 OQR88945.1 - 1.4e-14 54.3 5.5 2e-07 31.3 2.2 2.6 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 OQR88945.1 - 0.0042 16.5 11.3 0.0051 16.2 0.8 4.2 4 0 0 4 4 4 1 EF hand Cu-binding_MopE PF11617.8 OQR88945.1 - 0.031 14.4 0.4 0.38 10.9 0.0 2.5 2 0 0 2 2 2 0 Putative metal-binding motif Pkinase_Tyr PF07714.17 OQR88947.1 - 5.8e-07 29.1 0.0 7.4e-07 28.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase cNMP_binding PF00027.29 OQR88953.1 - 3.7e-33 113.5 0.2 9.1e-21 73.7 0.0 2.1 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain ABC_membrane PF00664.23 OQR88954.1 - 1.8e-40 139.3 13.9 2.3e-40 139.0 13.9 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region DUF4574 PF15141.6 OQR88954.1 - 0.11 12.4 0.3 0.4 10.6 0.0 2.0 2 0 0 2 2 2 0 Ubiquinol-cytochrome-c reductase complex assembly factor 3 GCP_N_terminal PF17681.1 OQR88956.1 - 0.011 15.4 0.4 4 7.0 0.5 2.2 1 1 0 2 2 2 0 Gamma tubulin complex component N-terminal Glutaredoxin2_C PF04399.13 OQR88956.1 - 0.016 15.0 0.0 6.1 6.7 0.0 2.8 3 0 0 3 3 3 0 Glutaredoxin 2, C terminal domain Ribonuc_red_2_N PF08471.10 OQR88956.1 - 0.075 13.2 0.0 0.23 11.7 0.0 1.8 2 0 0 2 2 2 0 Class II vitamin B12-dependent ribonucleotide reductase PTPlike_phytase PF14566.6 OQR88957.1 - 3.8e-79 264.3 0.4 9.7e-42 142.7 0.2 2.5 2 0 0 2 2 2 2 Inositol hexakisphosphate GST_C_3 PF14497.6 OQR88957.1 - 1.2e-08 35.0 0.0 7.8e-08 32.4 0.0 2.4 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 OQR88957.1 - 1.6e-08 34.5 0.0 2.3e-06 27.5 0.0 3.0 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain Ank_2 PF12796.7 OQR88957.1 - 7.7e-06 26.4 0.7 0.0037 17.8 0.2 3.8 2 1 3 5 5 4 2 Ankyrin repeats (3 copies) DSPc PF00782.20 OQR88957.1 - 0.00029 20.7 0.0 0.13 12.1 0.0 2.9 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Ank_5 PF13857.6 OQR88957.1 - 0.00043 20.5 0.5 0.82 10.1 0.0 3.9 3 1 1 4 4 4 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 OQR88957.1 - 0.00063 20.3 0.2 0.23 12.1 0.0 4.4 5 0 0 5 5 4 1 Ankyrin repeats (many copies) Y_phosphatase PF00102.27 OQR88957.1 - 0.00097 18.8 0.0 0.29 10.7 0.0 2.4 2 0 0 2 2 2 2 Protein-tyrosine phosphatase GST_N PF02798.20 OQR88957.1 - 0.001 19.4 0.0 0.0025 18.1 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 OQR88957.1 - 0.002 18.3 0.0 0.0079 16.4 0.0 2.1 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Y_phosphatase3 PF13350.6 OQR88957.1 - 0.0025 17.8 0.0 0.4 10.6 0.0 2.5 2 0 0 2 2 2 1 Tyrosine phosphatase family RRM_5 PF13893.6 OQR88957.1 - 0.05 13.2 0.1 0.53 9.9 0.0 2.4 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Laminin_II PF06009.12 OQR88957.1 - 0.41 10.6 2.2 2.9 7.9 1.6 2.3 2 0 0 2 2 2 0 Laminin Domain II Ank_3 PF13606.6 OQR88957.1 - 0.54 11.0 2.2 2.2e+02 3.0 0.0 5.2 5 0 0 5 5 4 0 Ankyrin repeat FR47 PF08445.10 OQR88958.1 - 0.00041 20.3 0.0 0.00091 19.1 0.0 1.6 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_1 PF00583.25 OQR88958.1 - 0.0011 19.2 0.0 0.0018 18.5 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 OQR88958.1 - 0.0024 18.3 0.0 0.0043 17.4 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 OQR88958.1 - 0.0098 15.8 0.0 0.019 14.9 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 OQR88958.1 - 0.025 15.3 0.0 0.043 14.5 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain RRM_1 PF00076.22 OQR88960.1 - 6.3e-23 80.4 1.5 1.2e-13 50.7 0.0 2.9 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 OQR88960.1 - 0.00031 20.5 0.0 0.19 11.6 0.0 2.7 2 0 0 2 2 2 2 Occluded RNA-recognition motif Lsm_interact PF05391.11 OQR88960.1 - 0.00053 19.4 1.1 0.0015 17.9 0.4 2.2 2 0 0 2 2 2 1 Lsm interaction motif CDC45 PF02724.14 OQR88960.1 - 0.15 10.4 7.5 0.046 12.0 3.8 1.8 2 0 0 2 2 2 0 CDC45-like protein CTP_transf_1 PF01148.20 OQR88961.1 - 3.2e-35 122.2 17.2 4.8e-33 115.1 13.4 2.3 2 1 0 2 2 2 2 Cytidylyltransferase family SPW PF03779.14 OQR88961.1 - 0.009 15.6 0.6 0.009 15.6 0.6 2.4 2 0 0 2 2 2 1 SPW repeat peroxidase PF00141.23 OQR88962.1 - 6.7e-05 22.7 0.1 0.11 12.2 0.0 2.1 1 1 1 2 2 2 2 Peroxidase DUF2517 PF10725.9 OQR88962.1 - 0.14 12.0 0.2 0.33 10.8 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2517) Complex1_LYR PF05347.15 OQR88963.1 - 3e-11 43.2 0.0 4.1e-11 42.8 0.0 1.2 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 OQR88963.1 - 0.0017 19.1 0.1 0.0021 18.8 0.1 1.2 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR_1 PF13232.6 OQR88963.1 - 0.036 14.7 0.0 0.046 14.3 0.0 1.1 1 0 0 1 1 1 0 Complex1_LYR-like Rad60-SLD PF11976.8 OQR88964.1 - 1e-33 115.0 4.6 6e-11 42.0 0.2 3.2 3 0 0 3 3 3 3 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 OQR88964.1 - 9.3e-19 67.0 5.1 2.5e-06 27.1 0.1 3.2 3 0 0 3 3 3 3 Ubiquitin family RBD PF02196.15 OQR88964.1 - 2.3e-07 30.8 0.2 0.037 14.1 0.0 2.7 3 0 0 3 3 3 2 Raf-like Ras-binding domain TUG-UBL1 PF11470.8 OQR88964.1 - 0.00014 22.0 0.2 0.11 12.7 0.0 3.4 3 0 0 3 3 3 1 TUG ubiquitin-like domain Cobl PF09469.10 OQR88964.1 - 0.0033 17.7 2.8 1.3 9.3 0.1 3.0 2 2 1 3 3 3 2 Cordon-bleu ubiquitin-like domain pP_pnuc_2 PF18166.1 OQR88964.1 - 0.037 14.1 0.4 1.3 9.1 0.5 2.8 1 1 2 3 3 3 0 Predicted pPIWI-associating nuclease FNIP_C PF14638.6 OQR88964.1 - 0.086 12.5 0.1 1.6 8.3 0.0 2.4 3 0 0 3 3 3 0 Folliculin-interacting protein C-terminus FlaG PF03646.15 OQR88964.1 - 0.19 11.9 2.8 2.1 8.5 0.2 2.8 3 0 0 3 3 3 0 FlaG protein zf-BED PF02892.15 OQR88965.1 - 0.0065 16.5 1.0 0.0065 16.5 1.0 2.2 2 0 0 2 2 2 1 BED zinc finger Peptidase_M48 PF01435.18 OQR88967.1 - 2.7e-20 73.0 0.0 3.5e-20 72.6 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M48 Peptidase_M48_N PF16491.5 OQR88967.1 - 9.8e-08 32.1 1.8 1.5e-07 31.5 1.8 1.2 1 0 0 1 1 1 1 CAAX prenyl protease N-terminal, five membrane helices DUF2268 PF10026.9 OQR88967.1 - 0.061 12.9 0.0 0.077 12.6 0.0 1.1 1 0 0 1 1 1 0 Predicted Zn-dependent protease (DUF2268) DUF2985 PF11204.8 OQR88969.1 - 2.5e-07 30.7 5.1 2.5e-07 30.7 5.1 2.1 2 1 0 2 2 2 1 Protein of unknown function (DUF2985) LapA_dom PF06305.11 OQR88969.1 - 0.001 18.8 2.8 0.06 13.2 0.0 2.4 2 0 0 2 2 2 1 Lipopolysaccharide assembly protein A domain Saf_2TM PF18303.1 OQR88969.1 - 0.013 15.1 2.7 0.57 9.8 0.3 3.0 1 1 2 3 3 3 0 SAVED-fused 2TM effector domain Mg_trans_NIPA PF05653.14 OQR88970.1 - 2.1e-29 102.6 12.1 2.7e-29 102.2 12.1 1.1 1 0 0 1 1 1 1 Magnesium transporter NIPA TMEM234 PF10639.9 OQR88970.1 - 0.00046 20.2 0.2 0.0014 18.6 0.2 1.9 1 0 0 1 1 1 1 Putative transmembrane family 234 Adipogenin PF15202.6 OQR88970.1 - 0.039 14.0 0.1 0.039 14.0 0.1 2.0 2 0 0 2 2 2 0 Adipogenin MgtE PF01769.16 OQR88971.1 - 3.2e-25 88.9 6.3 3.2e-25 88.9 6.3 2.9 2 1 1 3 3 3 1 Divalent cation transporter Ank_2 PF12796.7 OQR88972.1 - 5.1e-47 158.4 6.0 1.3e-13 51.4 0.1 4.6 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQR88972.1 - 2.1e-36 123.8 0.7 4.7e-07 30.2 0.0 7.5 3 2 3 7 7 7 7 Ankyrin repeats (many copies) Ank PF00023.30 OQR88972.1 - 1e-34 117.5 14.5 5.5e-05 23.4 0.1 9.4 8 1 1 9 9 9 8 Ankyrin repeat Ank_3 PF13606.6 OQR88972.1 - 6.8e-28 93.6 0.0 0.022 15.2 0.0 9.5 10 0 0 10 10 10 7 Ankyrin repeat Ank_5 PF13857.6 OQR88972.1 - 9.2e-21 73.6 7.0 0.00015 21.9 0.1 7.6 3 2 6 9 9 9 6 Ankyrin repeats (many copies) PEGA PF08308.11 OQR88972.1 - 0.16 11.9 0.4 22 5.0 0.1 2.9 3 0 0 3 3 3 0 PEGA domain Ank_2 PF12796.7 OQR88973.1 - 1e-41 141.4 7.5 4.9e-15 55.9 0.4 5.1 2 1 3 5 5 5 4 Ankyrin repeats (3 copies) Ank PF00023.30 OQR88973.1 - 7.1e-32 108.5 6.8 8.2e-06 26.0 0.1 8.6 9 0 0 9 9 9 6 Ankyrin repeat Ank_3 PF13606.6 OQR88973.1 - 7e-26 87.5 3.6 0.0032 17.8 0.0 9.2 8 1 1 9 9 9 5 Ankyrin repeat Ank_4 PF13637.6 OQR88973.1 - 2.2e-25 88.7 1.2 2.8e-05 24.6 0.0 8.0 3 2 5 8 8 8 7 Ankyrin repeats (many copies) Ank_5 PF13857.6 OQR88973.1 - 2.3e-20 72.4 3.7 0.00041 20.6 0.0 5.4 3 2 2 5 5 5 4 Ankyrin repeats (many copies) Shigella_OspC PF06128.11 OQR88973.1 - 0.015 15.0 1.1 0.043 13.5 0.1 2.0 1 1 1 2 2 2 0 Shigella flexneri OspC protein FTCD_C PF04961.12 OQR88974.1 - 0.041 13.7 1.2 0.076 12.8 1.2 1.4 1 0 0 1 1 1 0 Formiminotransferase-cyclodeaminase DUF4710 PF15828.5 OQR88974.1 - 1.3 9.2 6.8 3.2 7.9 6.8 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4710) Methyltransf_25 PF13649.6 OQR88975.1 - 1.3e-06 29.0 0.0 3.2e-06 27.8 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 OQR88975.1 - 3.3e-05 23.7 0.0 5e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OQR88975.1 - 0.00085 20.0 0.0 0.0013 19.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OQR88975.1 - 0.0017 19.0 0.0 0.0031 18.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_33 PF10017.9 OQR88975.1 - 0.0072 15.5 0.0 0.012 14.7 0.0 1.3 1 0 0 1 1 1 1 Histidine-specific methyltransferase, SAM-dependent Methyltransf_32 PF13679.6 OQR88975.1 - 0.014 15.4 0.0 0.022 14.7 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain TehB PF03848.14 OQR88975.1 - 0.041 13.3 0.0 0.062 12.7 0.0 1.2 1 0 0 1 1 1 0 Tellurite resistance protein TehB Methyltransf_23 PF13489.6 OQR88975.1 - 0.13 12.0 0.0 0.26 11.1 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain DUF3156 PF11354.8 OQR88976.1 - 0.049 13.5 0.1 0.12 12.3 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3156) HIG_1_N PF04588.13 OQR88978.1 - 1.1e-05 25.6 0.0 2e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 Hypoxia induced protein conserved region B PF02216.16 OQR88978.1 - 0.083 12.9 0.4 0.15 12.1 0.0 1.6 2 0 0 2 2 2 0 B domain Sin_N PF04801.13 OQR88981.1 - 8.9e-68 229.5 1.3 1.4e-67 228.8 1.3 1.3 1 1 0 1 1 1 1 Sin-like protein conserved region NUC130_3NT PF08158.12 OQR88981.1 - 0.0013 19.0 0.0 0.051 13.9 0.0 2.5 2 0 0 2 2 2 1 NUC130/3NT domain Pkinase PF00069.25 OQR88985.1 - 1e-63 215.2 0.0 1.8e-63 214.4 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQR88985.1 - 3.2e-49 167.6 0.0 6.8e-49 166.5 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase RhoGAP PF00620.27 OQR88985.1 - 1.7e-24 86.4 0.1 2.9e-24 85.6 0.1 1.4 1 0 0 1 1 1 1 RhoGAP domain Pkinase_fungal PF17667.1 OQR88985.1 - 6.3e-06 25.2 0.0 1.1e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase DbpA PF03880.15 OQR88985.1 - 0.0042 17.0 0.0 0.0096 15.9 0.0 1.5 1 0 0 1 1 1 1 DbpA RNA binding domain APH PF01636.23 OQR88985.1 - 0.024 14.6 0.0 3.3 7.5 0.0 2.6 1 1 1 2 2 2 0 Phosphotransferase enzyme family DUF4456 PF14644.6 OQR88985.1 - 0.055 13.2 0.1 0.1 12.3 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4456) Kinase-like PF14531.6 OQR88985.1 - 0.099 11.9 0.0 0.3 10.4 0.0 1.8 1 1 0 1 1 1 0 Kinase-like Sec15 PF04091.12 OQR88986.1 - 2.9e-28 99.2 2.5 1.7e-20 73.7 2.6 2.2 1 1 1 2 2 2 2 Exocyst complex subunit Sec15-like DIL PF01843.19 OQR88986.1 - 0.018 15.3 0.7 0.46 10.8 0.0 2.8 1 1 0 2 2 2 0 DIL domain Transferase PF02458.15 OQR88988.1 - 4e-19 68.6 0.0 7e-19 67.8 0.0 1.2 1 1 0 1 1 1 1 Transferase family YycI PF09648.10 OQR88988.1 - 0.15 11.7 0.0 0.26 10.8 0.0 1.3 1 0 0 1 1 1 0 YycH protein Arm PF00514.23 OQR88989.1 - 2.2e-20 71.9 22.3 0.00038 20.4 0.0 9.8 11 0 0 11 11 11 6 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 OQR88989.1 - 3.4e-10 40.2 0.3 0.013 16.0 0.1 5.6 6 1 1 7 7 7 2 HEAT-like repeat HEAT_2 PF13646.6 OQR88989.1 - 4.5e-10 39.8 0.9 0.019 15.4 0.0 4.5 5 0 0 5 5 5 3 HEAT repeats HEAT PF02985.22 OQR88989.1 - 2e-08 33.8 8.6 0.19 12.0 0.0 7.7 8 0 0 8 8 8 2 HEAT repeat Cnd1 PF12717.7 OQR88989.1 - 3.5e-06 27.2 1.3 1.5 8.9 0.0 3.6 2 1 1 3 3 3 3 non-SMC mitotic condensation complex subunit 1 WAPL PF07814.13 OQR88989.1 - 0.00082 18.3 0.4 0.00082 18.3 0.4 3.0 3 1 1 4 4 4 1 Wings apart-like protein regulation of heterochromatin Adaptin_N PF01602.20 OQR88989.1 - 0.017 13.7 0.4 0.017 13.7 0.4 3.1 2 2 1 3 3 3 0 Adaptin N terminal region RICTOR_N PF14664.6 OQR88989.1 - 0.019 14.0 9.2 0.043 12.8 0.6 3.8 3 2 1 4 4 4 0 Rapamycin-insensitive companion of mTOR, N-term Arm_2 PF04826.13 OQR88989.1 - 0.027 13.9 10.9 0.42 10.0 4.8 4.0 3 1 0 3 3 3 0 Armadillo-like DUF4572 PF15139.6 OQR88990.1 - 0.00013 22.0 0.2 0.0025 17.8 0.2 2.6 1 1 0 1 1 1 1 Domain of unknown function (DUF4572) RCC1 PF00415.18 OQR88992.1 - 9.4e-31 106.2 2.3 4.8e-10 39.9 0.2 6.0 5 1 1 6 6 6 3 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 OQR88992.1 - 7.8e-19 67.0 16.0 7.8e-07 28.7 0.4 4.8 4 0 0 4 4 4 4 Regulator of chromosome condensation (RCC1) repeat AAA-ATPase_like PF09820.9 OQR88992.1 - 0.26 10.7 1.4 0.39 10.1 1.4 1.2 1 0 0 1 1 1 0 Predicted AAA-ATPase Guanylate_cyc PF00211.20 OQR88998.1 - 5.6e-52 176.0 0.1 8.3e-52 175.5 0.1 1.3 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain HNOBA PF07701.14 OQR88998.1 - 0.013 15.0 0.1 0.02 14.3 0.1 1.3 1 0 0 1 1 1 0 Heme NO binding associated Kinesin PF00225.23 OQR88999.1 - 4.5e-106 354.5 0.4 4.5e-106 354.5 0.4 3.4 3 0 0 3 3 3 1 Kinesin motor domain Microtub_bd PF16796.5 OQR88999.1 - 4.5e-25 88.3 0.4 6.1e-23 81.4 0.0 4.4 3 0 0 3 3 3 1 Microtubule binding Ank_5 PF13857.6 OQR88999.1 - 0.00012 22.3 0.0 0.00029 21.1 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 OQR88999.1 - 0.00037 21.0 0.0 0.0013 19.3 0.0 1.9 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 OQR88999.1 - 0.0042 17.5 0.1 0.014 15.8 0.1 1.9 1 0 0 1 1 1 1 Ankyrin repeat MPLKIP PF15502.6 OQR88999.1 - 0.06 13.6 0.1 0.27 11.5 0.1 2.2 1 0 0 1 1 1 0 M-phase-specific PLK1-interacting protein Ank_3 PF13606.6 OQR88999.1 - 0.097 13.3 0.0 0.31 11.7 0.0 2.0 1 0 0 1 1 1 0 Ankyrin repeat Kinesin PF00225.23 OQR89001.1 - 5.5e-33 114.3 0.5 5.5e-33 114.3 0.5 1.9 2 0 0 2 2 2 1 Kinesin motor domain DUF4472 PF14739.6 OQR89001.1 - 2.7e-25 89.2 13.3 2.7e-25 89.2 13.3 4.5 3 1 0 3 3 3 1 Domain of unknown function (DUF4472) DUF2935 PF11155.8 OQR89001.1 - 7.3e-05 23.1 0.2 0.049 13.9 0.0 3.4 1 1 1 2 2 2 2 Domain of unknown function (DUF2935) Wzy_C PF04932.15 OQR89004.1 - 1.9 8.1 8.0 0.62 9.7 1.7 2.9 3 0 0 3 3 3 0 O-Antigen ligase DUF588 PF04535.12 OQR89005.1 - 0.019 14.8 0.4 0.025 14.4 0.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF588) G8 PF10162.9 OQR89010.1 - 1.7e-12 47.5 0.2 4.7e-12 46.1 0.2 1.7 1 0 0 1 1 1 1 G8 domain Beta_helix PF13229.6 OQR89010.1 - 7.4e-05 22.7 1.7 7.4e-05 22.7 1.7 3.6 3 1 1 4 4 4 2 Right handed beta helix region Pkinase PF00069.25 OQR89013.1 - 8.5e-18 64.7 0.0 9.3e-17 61.2 0.0 1.9 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQR89013.1 - 1.9e-17 63.4 0.0 1.5e-16 60.5 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase LRR_9 PF14580.6 OQR89014.1 - 4.8e-10 39.2 1.2 2.8e-09 36.7 1.2 1.8 1 1 0 1 1 1 1 Leucine-rich repeat LRR_8 PF13855.6 OQR89014.1 - 5.1e-10 39.0 7.5 1.2e-09 37.8 7.2 1.8 2 0 0 2 2 2 1 Leucine rich repeat LRR_4 PF12799.7 OQR89014.1 - 7.2e-05 23.1 13.1 0.0065 16.9 3.1 2.7 1 1 2 3 3 3 3 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 OQR89014.1 - 0.49 10.6 3.2 32 4.9 0.2 3.2 3 0 0 3 3 3 0 Leucine Rich repeat SelP_N PF04592.14 OQR89015.1 - 0.41 10.0 10.1 0.48 9.8 10.1 1.1 1 0 0 1 1 1 0 Selenoprotein P, N terminal region RAMP4 PF06624.12 OQR89017.1 - 4.9e-19 68.2 0.0 5.7e-19 67.9 0.0 1.0 1 0 0 1 1 1 1 Ribosome associated membrane protein RAMP4 Beta_protein PF14350.6 OQR89019.1 - 0.16 11.3 0.0 0.2 11.0 0.0 1.1 1 0 0 1 1 1 0 Beta protein FYVE PF01363.21 OQR89020.1 - 8.3e-11 41.9 9.5 4.1e-09 36.5 9.2 2.3 2 0 0 2 2 2 1 FYVE zinc finger PI3Ka PF00613.20 OQR89020.1 - 0.047 13.1 0.1 0.086 12.2 0.1 1.4 1 0 0 1 1 1 0 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PH_2 PF08458.10 OQR89020.1 - 0.054 13.8 0.1 0.11 12.9 0.1 1.5 1 0 0 1 1 1 0 Plant pleckstrin homology-like region PH PF00169.29 OQR89020.1 - 0.15 12.6 0.0 0.39 11.3 0.0 1.7 1 0 0 1 1 1 0 PH domain REJ PF02010.15 OQR89025.1 - 4.4e-49 167.5 8.6 4.4e-49 167.5 8.6 2.0 1 1 1 2 2 2 1 REJ domain Tetraspanin PF00335.20 OQR89025.1 - 1e-22 81.0 83.0 3.9e-11 43.1 7.3 6.4 4 1 2 6 6 6 5 Tetraspanin family EGF PF00008.27 OQR89025.1 - 0.0079 16.5 9.7 0.022 15.1 9.7 1.8 1 0 0 1 1 1 1 EGF-like domain GPS PF01825.21 OQR89025.1 - 0.089 13.3 7.8 0.37 11.4 7.8 2.2 1 0 0 1 1 1 0 GPCR proteolysis site, GPS, motif SIR2 PF02146.17 OQR89027.1 - 1.3e-26 93.6 0.5 2e-19 70.2 0.0 2.2 1 1 1 2 2 2 2 Sir2 family TPP_enzyme_M PF00205.22 OQR89027.1 - 0.056 13.2 0.0 0.99 9.1 0.0 2.2 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain EGF PF00008.27 OQR89029.1 - 0.00022 21.5 7.2 0.00022 21.5 7.2 4.1 4 0 0 4 4 4 1 EGF-like domain hEGF PF12661.7 OQR89029.1 - 0.0011 19.5 1.5 0.0011 19.5 1.5 4.4 4 0 0 4 4 4 1 Human growth factor-like EGF EGF_2 PF07974.13 OQR89029.1 - 0.0015 18.8 8.1 0.0015 18.8 8.1 5.1 5 0 0 5 5 5 2 EGF-like domain Utp14 PF04615.13 OQR89030.1 - 8.1e-97 325.6 57.5 8.1e-97 325.6 57.5 1.8 1 1 0 2 2 2 1 Utp14 protein GH97_C PF14509.6 OQR89030.1 - 0.062 13.5 0.6 0.45 10.8 0.6 2.6 1 0 0 1 1 1 0 Glycosyl-hydrolase 97 C-terminal, oligomerisation Phage_rep_O PF04492.13 OQR89030.1 - 0.076 13.6 0.1 0.19 12.3 0.1 1.7 1 0 0 1 1 1 0 Bacteriophage replication protein O Ribosomal_L28e PF01778.17 OQR89031.1 - 7.3e-38 129.9 1.7 7.3e-38 129.9 1.7 2.0 2 0 0 2 2 2 1 Ribosomal L28e protein family Mak16 PF04874.14 OQR89031.1 - 1.9e-30 105.4 15.9 1.9e-30 105.4 15.9 3.0 2 1 1 3 3 3 1 Mak16 protein C-terminal region BUD22 PF09073.10 OQR89031.1 - 9.8e-06 25.2 25.6 1.3e-05 24.8 25.6 1.1 1 0 0 1 1 1 1 BUD22 Nop14 PF04147.12 OQR89031.1 - 0.02 13.2 36.5 0.027 12.7 36.5 1.1 1 0 0 1 1 1 0 Nop14-like family Ribosomal_S11 PF00411.19 OQR89032.1 - 1e-45 154.6 2.2 1.4e-45 154.2 2.2 1.2 1 0 0 1 1 1 1 Ribosomal protein S11 DUF2252 PF10009.9 OQR89032.1 - 0.079 12.0 0.0 0.09 11.8 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2252) DUF4419 PF14388.6 OQR89033.1 - 1.9e-99 332.9 0.2 2.2e-99 332.7 0.2 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4419) Ank_2 PF12796.7 OQR89037.1 - 1.5e-19 70.4 9.8 2e-07 31.5 0.5 3.3 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQR89037.1 - 1.2e-14 54.4 4.7 2.8e-05 24.6 0.3 4.9 3 1 2 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQR89037.1 - 3e-11 42.5 3.0 2 9.3 0.0 6.9 5 2 2 7 7 7 3 Ankyrin repeat Ank_5 PF13857.6 OQR89037.1 - 4.2e-10 39.7 5.0 0.39 11.1 0.1 6.2 2 2 4 6 6 6 5 Ankyrin repeats (many copies) DUF5049 PF16468.5 OQR89037.1 - 0.0066 16.3 0.9 3.8 7.5 0.0 4.5 3 1 3 6 6 6 1 Domain of unknown function (DUF5049) Ank PF00023.30 OQR89037.1 - 0.067 13.7 0.8 11 6.7 0.1 3.8 1 1 1 2 2 2 0 Ankyrin repeat Aa_trans PF01490.18 OQR89039.1 - 1.3e-25 90.0 17.8 1.6e-25 89.7 17.8 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Tetraspanin PF00335.20 OQR89039.1 - 1.8 8.2 14.1 8.1 6.1 14.2 2.3 1 1 0 1 1 1 0 Tetraspanin family AAA_24 PF13479.6 OQR89041.1 - 0.062 13.0 0.0 0.087 12.5 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 OQR89043.1 - 3.1e-41 140.9 0.0 6.3e-41 139.9 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 OQR89043.1 - 7.1e-14 51.3 0.1 2.1e-13 49.8 0.1 1.8 1 0 0 1 1 1 1 AAA+ lid domain Prot_ATP_ID_OB PF16450.5 OQR89043.1 - 2e-10 40.5 0.1 5.6e-10 39.0 0.1 1.8 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_16 PF13191.6 OQR89043.1 - 7.1e-07 29.8 0.0 0.00059 20.3 0.1 2.5 1 1 1 2 2 2 1 AAA ATPase domain AAA_5 PF07728.14 OQR89043.1 - 1.5e-05 25.0 0.1 0.00015 21.8 0.1 2.5 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 OQR89043.1 - 2.1e-05 24.7 0.0 4.5e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 OQR89043.1 - 6.2e-05 23.3 0.1 0.038 14.3 0.0 2.6 1 1 1 2 2 2 1 AAA domain RuvB_N PF05496.12 OQR89043.1 - 8.4e-05 22.4 0.0 0.00021 21.1 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain DUF815 PF05673.13 OQR89043.1 - 0.0023 17.1 0.0 0.0046 16.2 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) Prot_ATP_OB_N PF17758.1 OQR89043.1 - 0.0024 17.5 0.2 0.011 15.4 0.0 2.1 3 0 0 3 3 1 1 Proteasomal ATPase OB N-terminal domain RNA_helicase PF00910.22 OQR89043.1 - 0.0025 18.2 0.0 0.0055 17.1 0.0 1.6 1 0 0 1 1 1 1 RNA helicase IstB_IS21 PF01695.17 OQR89043.1 - 0.0031 17.3 0.0 0.0071 16.1 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein Mg_chelatase PF01078.21 OQR89043.1 - 0.0048 16.3 0.0 0.0091 15.4 0.0 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_18 PF13238.6 OQR89043.1 - 0.0056 17.2 0.0 0.018 15.6 0.0 1.9 1 1 0 1 1 1 1 AAA domain TIP49 PF06068.13 OQR89043.1 - 0.0082 15.4 0.3 0.016 14.4 0.0 1.6 2 0 0 2 2 2 1 TIP49 P-loop domain AAA_28 PF13521.6 OQR89043.1 - 0.013 15.7 0.0 0.029 14.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 OQR89043.1 - 0.014 15.1 0.0 0.059 13.1 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 OQR89043.1 - 0.018 14.6 0.0 0.043 13.3 0.0 1.6 1 1 0 1 1 1 0 P-loop containing dynein motor region AAA_25 PF13481.6 OQR89043.1 - 0.02 14.5 0.4 0.055 13.0 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 OQR89043.1 - 0.026 14.7 0.0 0.058 13.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain ATPase PF06745.13 OQR89043.1 - 0.032 13.6 0.2 0.13 11.6 0.0 2.0 3 0 0 3 3 3 0 KaiC AAA_3 PF07726.11 OQR89043.1 - 0.034 14.0 0.0 0.085 12.7 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 OQR89043.1 - 0.035 13.8 0.0 0.11 12.3 0.0 1.8 1 1 0 1 1 1 0 Sigma-54 interaction domain PhoH PF02562.16 OQR89043.1 - 0.044 13.2 0.1 0.087 12.3 0.1 1.4 1 0 0 1 1 1 0 PhoH-like protein TsaE PF02367.17 OQR89043.1 - 0.056 13.4 0.0 0.12 12.4 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_14 PF13173.6 OQR89043.1 - 0.068 13.2 0.0 0.14 12.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain Parvo_NS1 PF01057.17 OQR89043.1 - 0.083 12.0 0.0 0.16 11.0 0.0 1.4 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 NACHT PF05729.12 OQR89043.1 - 0.13 12.2 0.0 0.39 10.6 0.0 1.8 1 1 0 1 1 1 0 NACHT domain NPC1_N PF16414.5 OQR89045.1 - 1.7e-14 54.0 19.4 3.3e-14 53.1 19.4 1.4 1 1 0 1 1 1 1 Niemann-Pick C1 N terminus Folate_rec PF03024.14 OQR89045.1 - 0.00016 21.6 6.2 0.00016 21.6 6.2 2.0 2 1 1 3 3 3 1 Folate receptor family RNA_pol_Rpb1_1 PF04997.12 OQR89045.1 - 0.15 11.4 0.4 0.27 10.5 0.0 1.5 2 0 0 2 2 2 0 RNA polymerase Rpb1, domain 1 RRM_1 PF00076.22 OQR89046.1 - 1.1e-18 66.8 0.0 1.9e-18 66.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_8 PF11835.8 OQR89046.1 - 0.053 13.7 0.0 0.094 12.9 0.0 1.4 1 1 0 1 1 1 0 RRM-like domain PAP2 PF01569.21 OQR89049.1 - 3.3e-19 69.0 4.1 3.3e-19 69.0 4.1 2.2 1 1 1 2 2 2 1 PAP2 superfamily PAP2_3 PF14378.6 OQR89049.1 - 0.0061 16.3 15.5 0.011 15.4 10.5 3.5 2 1 0 2 2 2 1 PAP2 superfamily PAP2_C PF14360.6 OQR89049.1 - 0.011 16.3 0.3 0.011 16.3 0.3 2.9 3 0 0 3 3 3 0 PAP2 superfamily C-terminal Gly_rich PF12810.7 OQR89051.1 - 3.9e-14 53.1 52.3 6e-14 52.6 52.3 1.2 1 0 0 1 1 1 1 Glycine rich protein WW PF00397.26 OQR89051.1 - 4.1e-11 42.8 11.5 4.5e-05 23.5 0.6 4.5 4 0 0 4 4 4 4 WW domain Erf4 PF10256.9 OQR89055.1 - 5.1e-06 26.6 0.0 8.9e-06 25.8 0.0 1.4 1 0 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family Motile_Sperm PF00635.26 OQR89055.1 - 1.9e-05 24.5 0.0 2.6e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 MSP (Major sperm protein) domain TPR_2 PF07719.17 OQR89056.1 - 1.6e-36 121.4 10.1 2.9e-05 23.8 0.1 10.3 10 0 0 10 10 10 7 Tetratricopeptide repeat TPR_1 PF00515.28 OQR89056.1 - 2.6e-33 112.5 8.0 1e-05 25.1 0.0 8.3 8 0 0 8 8 8 6 Tetratricopeptide repeat TPR_8 PF13181.6 OQR89056.1 - 7.3e-30 100.7 5.7 0.00072 19.6 0.1 8.9 9 0 0 9 9 9 6 Tetratricopeptide repeat TPR_11 PF13414.6 OQR89056.1 - 1.4e-24 85.4 6.4 7.3e-07 28.8 0.0 8.3 3 2 5 8 8 8 5 TPR repeat TPR_12 PF13424.6 OQR89056.1 - 4.8e-20 71.6 7.9 4.2e-06 26.9 0.2 6.7 6 1 1 7 7 7 5 Tetratricopeptide repeat TPR_16 PF13432.6 OQR89056.1 - 1.7e-16 60.6 0.1 0.0039 17.8 0.0 5.3 3 2 3 6 6 6 4 Tetratricopeptide repeat TPR_7 PF13176.6 OQR89056.1 - 8.2e-15 53.7 2.3 0.061 13.4 0.0 7.7 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_17 PF13431.6 OQR89056.1 - 2.1e-13 49.6 7.6 0.014 15.7 0.0 7.9 9 0 0 9 9 7 2 Tetratricopeptide repeat TPR_14 PF13428.6 OQR89056.1 - 1.4e-12 47.3 3.2 0.0047 17.6 0.0 7.6 5 3 4 9 9 6 2 Tetratricopeptide repeat ANAPC3 PF12895.7 OQR89056.1 - 1.6e-11 44.2 12.0 0.00042 20.5 0.1 6.3 2 2 2 5 5 5 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.6 OQR89056.1 - 1.7e-11 44.1 0.0 0.0012 18.9 0.0 5.0 1 1 5 6 6 6 4 Tetratricopeptide repeat TPR_19 PF14559.6 OQR89056.1 - 6.3e-10 39.4 1.4 0.66 10.5 0.0 6.8 5 3 2 7 7 7 2 Tetratricopeptide repeat TPR_6 PF13174.6 OQR89056.1 - 8.9e-07 29.2 10.0 16 6.4 0.0 8.6 10 0 0 10 10 9 0 Tetratricopeptide repeat NARP1 PF12569.8 OQR89056.1 - 2.4e-05 23.4 0.6 0.42 9.5 0.0 3.5 2 1 2 4 4 4 2 NMDA receptor-regulated protein 1 TPR_15 PF13429.6 OQR89056.1 - 7e-05 22.2 0.1 4.5 6.4 0.0 4.0 2 1 2 4 4 4 2 Tetratricopeptide repeat TPR_10 PF13374.6 OQR89056.1 - 0.00056 19.7 15.4 6.6 6.7 0.0 7.2 9 0 0 9 9 7 2 Tetratricopeptide repeat TPR_3 PF07720.12 OQR89056.1 - 0.00065 19.6 5.9 22 5.2 0.1 6.0 5 0 0 5 5 5 0 Tetratricopeptide repeat F-box-like PF12937.7 OQR89056.1 - 0.0086 16.0 0.0 0.027 14.4 0.0 1.8 1 0 0 1 1 1 1 F-box-like PknG_TPR PF16918.5 OQR89056.1 - 0.032 13.0 0.1 5.1 5.7 0.0 2.3 2 0 0 2 2 2 0 Protein kinase G tetratricopeptide repeat BTAD PF03704.17 OQR89056.1 - 0.049 14.1 0.3 0.34 11.4 0.1 2.4 2 0 0 2 2 2 0 Bacterial transcriptional activator domain DUF3808 PF10300.9 OQR89056.1 - 0.069 11.9 2.0 1.3 7.7 0.0 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF3808) TPR_MalT PF17874.1 OQR89056.1 - 0.091 12.1 0.0 1.6 8.0 0.0 2.9 3 0 0 3 3 3 0 MalT-like TPR region SNAP PF14938.6 OQR89056.1 - 0.13 11.6 1.9 2.7 7.3 0.1 3.4 3 1 0 3 3 3 0 Soluble NSF attachment protein, SNAP Fis1_TPR_C PF14853.6 OQR89056.1 - 0.56 10.3 6.0 20 5.4 0.0 4.5 4 1 1 5 5 5 0 Fis1 C-terminal tetratricopeptide repeat GAF PF01590.26 OQR89058.1 - 4.6e-11 43.5 0.0 8e-11 42.7 0.0 1.4 1 0 0 1 1 1 1 GAF domain GAF_3 PF13492.6 OQR89058.1 - 3.7e-06 27.3 0.0 1.1e-05 25.8 0.0 1.9 1 0 0 1 1 1 1 GAF domain LRRFIP PF09738.9 OQR89058.1 - 0.05 13.1 21.4 0.094 12.2 21.4 1.4 1 0 0 1 1 1 0 LRRFIP family CEP63 PF17045.5 OQR89058.1 - 0.081 12.8 22.4 0.14 12.0 22.4 1.3 1 0 0 1 1 1 0 Centrosomal protein of 63 kDa ADIP PF11559.8 OQR89058.1 - 0.29 11.2 25.6 0.33 11.0 8.2 2.4 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding DUF641 PF04859.12 OQR89058.1 - 1 9.7 14.4 1.2 9.5 1.0 2.5 2 0 0 2 2 2 0 Plant protein of unknown function (DUF641) DUF1664 PF07889.12 OQR89058.1 - 4 7.5 14.3 3.6 7.7 3.5 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) ATG16 PF08614.11 OQR89058.1 - 4.3 7.5 25.4 6.6 6.9 8.2 2.4 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) BST2 PF16716.5 OQR89058.1 - 6.7 7.4 18.2 8.7 7.0 3.2 2.8 2 0 0 2 2 2 0 Bone marrow stromal antigen 2 NPIP PF06409.11 OQR89058.1 - 6.8 5.7 12.8 0.42 9.6 2.7 2.2 2 0 0 2 2 2 0 Nuclear pore complex interacting protein (NPIP) YabA PF06156.13 OQR89058.1 - 8.7 7.0 26.7 0.043 14.5 8.0 3.0 2 1 1 3 3 2 0 Initiation control protein YabA GDPD PF03009.17 OQR89061.1 - 4.2e-16 59.4 0.0 5e-16 59.2 0.0 1.1 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family MatE PF01554.18 OQR89062.1 - 3.5e-52 176.3 29.0 3.8e-28 98.2 8.2 2.2 2 0 0 2 2 2 2 MatE Polysacc_synt_C PF14667.6 OQR89062.1 - 0.00061 19.9 16.7 0.00061 19.9 16.7 4.0 3 1 2 5 5 5 2 Polysaccharide biosynthesis C-terminal domain DUF3311 PF11755.8 OQR89062.1 - 0.02 14.8 1.0 1.3 9.1 0.1 3.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3311) FERM_M PF00373.18 OQR89063.1 - 0.094 13.1 2.1 0.12 12.8 1.5 1.5 1 1 0 1 1 1 0 FERM central domain Peptidase_C1 PF00112.23 OQR89065.1 - 2.5e-95 318.7 22.5 3.3e-62 210.4 6.1 2.5 3 0 0 3 3 3 2 Papain family cysteine protease PT PF04886.12 OQR89065.1 - 1.1e-08 34.5 21.9 3.4e-05 23.3 21.9 2.5 1 1 0 1 1 1 1 PT repeat Peptidase_C1_2 PF03051.15 OQR89065.1 - 2e-05 23.6 4.5 0.33 9.7 0.2 3.2 3 0 0 3 3 3 3 Peptidase C1-like family SMC_ScpB PF04079.16 OQR89065.1 - 0.011 15.4 0.1 0.45 10.1 0.1 2.4 2 0 0 2 2 2 0 Segregation and condensation complex subunit ScpB DUF4074 PF13293.6 OQR89065.1 - 0.073 13.4 0.3 12 6.3 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4074) Inhibitor_I29 PF08246.12 OQR89065.1 - 0.45 11.0 2.9 10 6.6 0.1 2.5 2 0 0 2 2 2 0 Cathepsin propeptide inhibitor domain (I29) Trypan_PARP PF05887.11 OQR89065.1 - 4.9 7.1 10.5 11 6.0 10.5 1.5 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Glyco_hydro_6 PF01341.17 OQR89067.1 - 7.1e-14 52.2 0.0 8.2e-14 52.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 6 SLATT_3 PF18184.1 OQR89067.1 - 0.089 12.9 0.0 0.12 12.5 0.0 1.1 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain 3 Torsin PF06309.11 OQR89071.1 - 5.3e-12 45.9 0.1 4.2e-11 43.0 0.0 2.3 2 1 0 2 2 2 1 Torsin AAA_2 PF07724.14 OQR89071.1 - 6.7e-08 32.8 1.1 1.1e-07 32.1 0.2 1.9 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA PF00004.29 OQR89071.1 - 1.9e-07 31.6 0.6 2.1e-06 28.2 0.1 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 OQR89071.1 - 1.4e-05 25.1 0.1 3.6e-05 23.8 0.1 1.6 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 OQR89071.1 - 7.4e-05 23.0 0.2 0.00046 20.5 0.2 2.3 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 OQR89071.1 - 0.00049 20.2 0.7 0.0026 17.8 0.7 2.1 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_14 PF13173.6 OQR89071.1 - 0.00092 19.2 0.1 0.0023 18.0 0.1 1.8 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 OQR89071.1 - 0.0046 16.7 0.1 0.0065 16.2 0.1 1.3 1 0 0 1 1 1 1 AAA domain AAA_23 PF13476.6 OQR89071.1 - 0.0086 16.6 0.2 0.015 15.8 0.2 1.5 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.6 OQR89071.1 - 0.015 14.8 0.1 0.33 10.5 0.0 2.2 1 1 1 2 2 2 0 AAA domain Csa1 PF06023.12 OQR89071.1 - 0.032 13.6 0.1 0.062 12.6 0.1 1.4 1 0 0 1 1 1 0 CRISPR-associated exonuclease Csa1 Mg_chelatase PF01078.21 OQR89071.1 - 0.043 13.2 0.4 0.85 9.0 0.4 2.2 1 1 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_18 PF13238.6 OQR89071.1 - 0.05 14.2 0.0 0.12 12.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain APS_kinase PF01583.20 OQR89071.1 - 0.054 13.4 0.0 0.1 12.5 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase PhoH PF02562.16 OQR89071.1 - 0.091 12.2 0.4 0.88 9.0 0.0 2.3 2 1 0 2 2 2 0 PhoH-like protein DUF2075 PF09848.9 OQR89071.1 - 0.11 11.7 0.6 0.36 10.0 0.6 1.8 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) SRP54 PF00448.22 OQR89071.1 - 0.18 11.4 1.5 0.36 10.4 1.5 1.8 1 1 0 1 1 1 0 SRP54-type protein, GTPase domain Ank_5 PF13857.6 OQR89073.1 - 7.6e-18 64.3 0.2 4.8e-08 33.1 0.0 3.0 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 OQR89073.1 - 1.8e-16 60.5 0.1 3e-08 34.1 0.0 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OQR89073.1 - 1.5e-12 46.5 0.0 0.00024 21.3 0.0 3.2 3 0 0 3 3 3 3 Ankyrin repeat Ank PF00023.30 OQR89073.1 - 9.5e-12 44.8 0.6 0.0006 20.1 0.0 3.3 3 0 0 3 3 3 3 Ankyrin repeat Ank_4 PF13637.6 OQR89073.1 - 3.7e-11 43.3 0.1 0.00039 20.9 0.0 3.1 3 0 0 3 3 3 3 Ankyrin repeats (many copies) ABC2_membrane PF01061.24 OQR89074.1 - 1.8e-32 112.5 28.6 1.8e-32 112.5 28.6 1.5 2 0 0 2 2 2 1 ABC-2 type transporter ABC2_membrane_3 PF12698.7 OQR89074.1 - 0.025 13.7 26.8 0.0094 15.1 23.9 1.7 1 1 1 2 2 2 0 ABC-2 family transporter protein DUF2070 PF09843.9 OQR89074.1 - 2.3 6.4 15.6 3 6.0 15.6 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) ABC_tran PF00005.27 OQR89075.1 - 5.3e-14 52.9 0.0 8e-14 52.3 0.0 1.3 1 0 0 1 1 1 1 ABC transporter Zeta_toxin PF06414.12 OQR89075.1 - 0.00064 19.1 0.0 0.0011 18.3 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin AAA_29 PF13555.6 OQR89075.1 - 0.0062 16.3 0.3 0.016 15.0 0.3 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.6 OQR89075.1 - 0.012 16.0 0.1 0.029 14.7 0.1 1.9 1 1 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 OQR89075.1 - 0.022 15.1 0.0 0.047 14.0 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_5 PF07728.14 OQR89075.1 - 0.036 14.1 0.0 0.073 13.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) DUF815 PF05673.13 OQR89075.1 - 0.039 13.1 0.0 0.059 12.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) RsgA_GTPase PF03193.16 OQR89075.1 - 0.039 13.9 0.1 0.071 13.0 0.1 1.4 1 0 0 1 1 1 0 RsgA GTPase MMR_HSR1 PF01926.23 OQR89075.1 - 0.08 13.0 0.0 0.16 12.1 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase SMC_N PF02463.19 OQR89075.1 - 0.084 12.3 0.1 3 7.2 0.0 2.2 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain Ploopntkinase3 PF18751.1 OQR89075.1 - 0.11 12.5 0.1 0.22 11.4 0.1 1.5 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 AAA_18 PF13238.6 OQR89075.1 - 0.11 13.1 0.0 0.19 12.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain STAT_bind PF02864.15 OQR89080.1 - 0.0096 16.5 0.6 0.011 16.2 0.6 1.1 1 0 0 1 1 1 1 STAT protein, DNA binding domain DUF1759 PF03564.15 OQR89080.1 - 0.078 12.9 1.1 0.23 11.4 0.2 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1759) ENTH PF01417.20 OQR89081.1 - 6.7e-16 58.5 0.0 4.1e-09 36.6 0.0 2.3 2 0 0 2 2 2 2 ENTH domain ANTH PF07651.16 OQR89081.1 - 0.00025 20.1 0.8 0.03 13.3 0.0 2.5 3 0 0 3 3 3 2 ANTH domain HEAT PF02985.22 OQR89081.1 - 0.0032 17.6 0.1 45 4.7 0.0 4.4 4 0 0 4 4 4 0 HEAT repeat SIL1 PF16782.5 OQR89081.1 - 0.09 12.0 0.0 1.2 8.3 0.0 2.1 2 0 0 2 2 2 0 Nucleotide exchange factor SIL1 PX PF00787.24 OQR89083.1 - 5.7e-08 32.7 0.0 1.8e-07 31.1 0.0 1.8 1 1 0 1 1 1 1 PX domain Laminin_G_3 PF13385.6 OQR89084.1 - 0.038 14.1 0.1 0.099 12.8 0.0 1.8 2 0 0 2 2 2 0 Concanavalin A-like lectin/glucanases superfamily ATP13 PF12921.7 OQR89084.1 - 0.11 12.4 0.1 0.23 11.3 0.1 1.5 1 0 0 1 1 1 0 Mitochondrial ATPase expression DUF2235 PF09994.9 OQR89086.1 - 1.1e-56 192.3 0.1 1.9e-56 191.6 0.0 1.4 2 0 0 2 2 2 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) Salt_tol_Pase PF09506.10 OQR89086.1 - 0.014 14.2 0.0 0.022 13.6 0.0 1.2 1 0 0 1 1 1 0 Glucosylglycerol-phosphate phosphatase (Salt_tol_Pase) DUF5540 PF17694.1 OQR89089.1 - 0.091 13.3 0.6 0.24 12.0 0.6 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5540) Phage_sheath_1 PF04984.14 OQR89089.1 - 0.14 12.0 0.1 0.44 10.4 0.0 1.8 2 0 0 2 2 2 0 Phage tail sheath protein subtilisin-like domain Phg_2220_C PF09524.10 OQR89089.1 - 0.46 10.6 2.9 16 5.7 0.0 3.3 3 0 0 3 3 3 0 Conserved phage C-terminus (Phg_2220_C) Aa_trans PF01490.18 OQR89090.1 - 1.2e-41 142.8 23.7 1.6e-41 142.4 23.7 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Thioredoxin PF00085.20 OQR89093.1 - 3.3e-34 117.0 0.0 3.1e-18 65.6 0.0 3.3 3 1 0 3 3 3 2 Thioredoxin Thioredoxin_8 PF13905.6 OQR89093.1 - 1.1e-08 35.2 0.4 0.057 13.7 0.0 4.6 3 2 2 5 5 5 2 Thioredoxin-like Thioredoxin_6 PF13848.6 OQR89093.1 - 7.8e-07 29.2 0.0 0.043 13.7 0.0 2.3 2 0 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_7 PF13899.6 OQR89093.1 - 1.1e-06 28.7 0.0 0.0087 16.2 0.0 2.6 2 0 0 2 2 2 2 Thioredoxin-like Thioredoxin_2 PF13098.6 OQR89093.1 - 2.8e-06 27.7 0.2 0.017 15.5 0.0 3.8 3 1 0 3 3 3 2 Thioredoxin-like domain AhpC-TSA PF00578.21 OQR89093.1 - 4.8e-06 26.5 0.0 0.012 15.6 0.0 2.4 2 0 0 2 2 2 2 AhpC/TSA family OST3_OST6 PF04756.13 OQR89093.1 - 4.1e-05 23.1 0.0 0.0016 17.9 0.0 2.2 1 1 1 2 2 2 1 OST3 / OST6 family, transporter family TraF PF13728.6 OQR89093.1 - 9.8e-05 22.3 0.0 0.0082 16.0 0.0 2.3 2 0 0 2 2 2 1 F plasmid transfer operon protein Thioredoxin_9 PF14595.6 OQR89093.1 - 0.00067 19.4 0.0 0.64 9.8 0.0 2.4 2 0 0 2 2 2 2 Thioredoxin Redoxin PF08534.10 OQR89093.1 - 0.0025 17.5 0.0 0.69 9.6 0.0 2.3 2 0 0 2 2 2 2 Redoxin HyaE PF07449.11 OQR89093.1 - 0.037 14.0 0.0 3.7 7.6 0.0 2.9 3 0 0 3 3 3 0 Hydrogenase-1 expression protein HyaE Thioredoxin PF00085.20 OQR89094.1 - 5.6e-11 42.3 0.0 8.3e-11 41.8 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin TraF PF13728.6 OQR89094.1 - 0.00013 21.8 0.0 0.00021 21.2 0.0 1.2 1 0 0 1 1 1 1 F plasmid transfer operon protein Thioredoxin_2 PF13098.6 OQR89094.1 - 0.0017 18.8 0.2 0.06 13.8 0.2 2.2 1 1 0 1 1 1 1 Thioredoxin-like domain OST3_OST6 PF04756.13 OQR89094.1 - 0.0066 15.8 0.0 0.0086 15.5 0.0 1.2 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family HyaE PF07449.11 OQR89094.1 - 0.03 14.3 0.0 0.054 13.5 0.0 1.4 1 0 0 1 1 1 0 Hydrogenase-1 expression protein HyaE AAA_8 PF12780.7 OQR89096.1 - 1e-91 306.9 0.0 2e-91 305.9 0.0 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 Dynein_C PF18199.1 OQR89096.1 - 2e-77 260.4 0.0 4.2e-77 259.4 0.0 1.6 1 0 0 1 1 1 1 Dynein heavy chain C-terminal domain MT PF12777.7 OQR89096.1 - 4.5e-74 249.5 13.7 8.5e-74 248.6 13.7 1.5 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_9 PF12781.7 OQR89096.1 - 2.8e-71 239.2 0.8 2.8e-71 239.2 0.8 2.5 2 0 0 2 2 2 1 ATP-binding dynein motor region AAA_7 PF12775.7 OQR89096.1 - 8.5e-53 178.5 0.2 4.1e-50 169.8 0.1 3.5 3 0 0 3 3 3 1 P-loop containing dynein motor region AAA_lid_11 PF18198.1 OQR89096.1 - 2.7e-50 170.4 0.2 8.5e-49 165.5 0.0 2.4 2 0 0 2 2 2 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 OQR89096.1 - 2.6e-31 108.2 0.0 1.4e-30 105.8 0.0 2.4 2 0 0 2 2 1 1 Dynein heavy chain region D6 P-loop domain AAA_lid_1 PF17857.1 OQR89096.1 - 1.6e-23 82.8 0.2 8.6e-23 80.5 0.2 2.3 1 0 0 1 1 1 1 AAA+ lid domain Dynein_AAA_lid PF17852.1 OQR89096.1 - 1.4e-17 64.0 2.4 1.5e-16 60.6 3.4 2.3 2 0 0 2 2 2 1 Dynein heavy chain AAA lid domain AAA_5 PF07728.14 OQR89096.1 - 7.2e-17 61.7 0.0 1.7e-07 31.3 0.0 4.5 3 0 0 3 3 3 3 AAA domain (dynein-related subfamily) AAA_6 PF12774.7 OQR89096.1 - 3e-11 42.9 0.0 6.9e-07 28.5 0.0 3.6 3 1 0 3 3 3 2 Hydrolytic ATP binding site of dynein motor region AAA_16 PF13191.6 OQR89096.1 - 4.9e-07 30.3 0.0 0.71 10.2 0.0 4.0 3 0 0 3 3 3 2 AAA ATPase domain AAA_18 PF13238.6 OQR89096.1 - 2e-05 25.1 0.1 1.6 9.3 0.0 4.6 4 0 0 4 4 4 1 AAA domain AAA_22 PF13401.6 OQR89096.1 - 0.00011 22.5 0.0 0.52 10.6 0.0 3.4 3 0 0 3 3 3 2 AAA domain AAA PF00004.29 OQR89096.1 - 0.0005 20.5 0.1 1.6 9.2 0.0 4.2 4 0 0 4 4 3 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 OQR89096.1 - 0.00068 19.8 0.6 0.53 10.4 0.0 4.2 5 0 0 5 5 4 1 AAA domain AAA_19 PF13245.6 OQR89096.1 - 0.00088 19.6 0.2 0.19 12.1 0.1 3.6 3 1 0 3 3 2 1 AAA domain Sigma54_activat PF00158.26 OQR89096.1 - 0.0032 17.2 0.0 0.32 10.7 0.0 2.8 2 0 0 2 2 2 1 Sigma-54 interaction domain T2SSE PF00437.20 OQR89096.1 - 0.0035 16.5 0.0 0.16 11.0 0.0 3.1 3 0 0 3 3 3 1 Type II/IV secretion system protein Actin PF00022.19 OQR89097.1 - 5.1e-96 321.8 0.0 3.6e-94 315.7 0.0 2.0 1 1 0 1 1 1 1 Actin Phage_pRha PF09669.10 OQR89097.1 - 0.18 12.3 0.0 8.5 7.0 0.0 2.9 3 0 0 3 3 3 0 Phage regulatory protein Rha (Phage_pRha) BT1 PF03092.16 OQR89098.1 - 1.4e-22 79.6 28.0 4.7e-10 38.3 1.6 5.9 5 1 0 6 6 6 5 BT1 family PUCC PF03209.15 OQR89098.1 - 1.6e-06 27.4 1.7 0.047 12.7 0.2 3.1 2 0 0 2 2 2 2 PUCC protein Cu_amine_oxidN2 PF02727.16 OQR89098.1 - 0.00076 19.7 0.0 0.26 11.6 0.0 2.3 2 0 0 2 2 2 2 Copper amine oxidase, N2 domain DUF1325 PF07039.11 OQR89098.1 - 0.0018 18.3 0.1 2.6 8.1 0.0 2.5 2 0 0 2 2 2 2 SGF29 tudor-like domain RasGEF PF00617.19 OQR89099.1 - 1.7e-21 77.3 0.2 5.6e-21 75.5 0.0 2.0 2 0 0 2 2 2 1 RasGEF domain Acyl_transf_3 PF01757.22 OQR89101.1 - 6.1e-05 22.2 0.5 9.5e-05 21.6 0.3 1.5 1 1 0 1 1 1 1 Acyltransferase family AhpC-TSA PF00578.21 OQR89102.1 - 4.6e-10 39.5 0.1 7.9e-10 38.7 0.1 1.5 1 1 0 1 1 1 1 AhpC/TSA family Thioredoxin_2 PF13098.6 OQR89102.1 - 6.3e-06 26.6 0.1 1.4e-05 25.4 0.1 1.6 1 1 0 1 1 1 1 Thioredoxin-like domain Redoxin PF08534.10 OQR89102.1 - 7.1e-06 25.8 0.1 1.2e-05 25.1 0.1 1.5 1 1 0 1 1 1 1 Redoxin Thioredoxin PF00085.20 OQR89102.1 - 3.6e-05 23.7 0.4 0.00016 21.6 0.3 2.0 1 1 0 2 2 2 1 Thioredoxin Thioredoxin_8 PF13905.6 OQR89102.1 - 0.0019 18.5 0.9 0.0098 16.2 0.9 2.0 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin_7 PF13899.6 OQR89102.1 - 0.043 14.0 0.3 0.11 12.7 0.1 2.0 2 1 0 2 2 2 0 Thioredoxin-like zf_C2H2_ZHX PF18387.1 OQR89102.1 - 0.13 11.9 1.4 0.34 10.6 1.4 1.7 1 1 0 1 1 1 0 Zinc-fingers and homeoboxes C2H2 finger domain Orn_Arg_deC_N PF02784.16 OQR89103.1 - 8.8e-39 133.4 0.0 1.1e-38 133.0 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.22 OQR89103.1 - 3.3e-19 68.9 0.0 3.7e-19 68.8 0.0 1.3 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain ABC_membrane PF00664.23 OQR89107.1 - 7e-48 163.6 14.5 8.5e-48 163.4 14.5 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region PhoR PF11808.8 OQR89107.1 - 0.25 11.8 2.1 0.25 11.8 0.3 2.0 2 0 0 2 2 2 0 Phosphate regulon sensor protein PhoR Glyco_hydro_1 PF00232.18 OQR89110.1 - 6.7e-62 209.4 0.2 7.4e-62 209.2 0.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 FYVE PF01363.21 OQR89112.1 - 5.4e-12 45.7 13.5 5.4e-12 45.7 13.5 1.7 2 0 0 2 2 2 1 FYVE zinc finger Cupin_4 PF08007.12 OQR89112.1 - 0.012 15.2 0.1 0.021 14.3 0.1 1.4 1 0 0 1 1 1 0 Cupin superfamily protein FYVE_2 PF02318.16 OQR89112.1 - 0.052 13.8 5.4 0.13 12.5 5.4 1.7 1 0 0 1 1 1 0 FYVE-type zinc finger Enolase_N PF03952.16 OQR89112.1 - 0.093 12.9 0.1 0.21 11.8 0.1 1.5 1 0 0 1 1 1 0 Enolase, N-terminal domain DUF4792 PF16040.5 OQR89112.1 - 0.096 12.6 0.0 0.34 10.8 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4792) FYVE PF01363.21 OQR89113.1 - 7.1e-12 45.3 11.0 1.8e-11 44.0 11.0 1.7 1 0 0 1 1 1 1 FYVE zinc finger HpaB_N PF11794.8 OQR89113.1 - 0.15 11.7 0.1 1 9.0 0.0 2.1 2 0 0 2 2 2 0 4-hydroxyphenylacetate 3-hydroxylase N terminal FYVE_2 PF02318.16 OQR89113.1 - 0.99 9.6 13.9 0.083 13.1 8.0 2.2 2 1 0 3 3 3 0 FYVE-type zinc finger C1_1 PF00130.22 OQR89113.1 - 1.1 9.2 11.4 0.43 10.5 8.2 2.0 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-RING_UBOX PF13445.6 OQR89113.1 - 1.4 9.0 8.9 3.9 7.6 8.9 1.9 1 0 0 1 1 1 0 RING-type zinc-finger Glyco_hydro_53 PF07745.13 OQR89114.1 - 0.0016 17.5 0.0 0.0031 16.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 53 FeoB_associated PF12669.7 OQR89114.1 - 0.15 12.5 0.9 1.2 9.6 0.1 2.3 2 0 0 2 2 2 0 FeoB-associated Cys-rich membrane protein Glyco_hydro_17 PF00332.18 OQR89114.1 - 0.54 9.8 4.3 0.93 9.0 2.8 2.1 1 1 1 2 2 2 0 Glycosyl hydrolases family 17 SOG2 PF10428.9 OQR89114.1 - 1.1 8.4 9.8 1.5 8.0 9.8 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein PRD1_DD PF11087.8 OQR89114.1 - 3.5 7.4 10.8 0.11 12.2 1.2 2.7 2 0 0 2 2 2 0 PRD1 phage membrane DNA delivery DEC-1_N PF04625.13 OQR89114.1 - 8.5 5.3 16.6 14 4.5 16.6 1.3 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region Cupin_8 PF13621.6 OQR89115.1 - 5e-20 72.3 2.6 1e-19 71.3 2.6 1.5 1 0 0 1 1 1 1 Cupin-like domain M20_dimer PF07687.14 OQR89115.1 - 5.8e-12 45.5 0.3 1.3e-11 44.3 0.1 1.7 2 0 0 2 2 2 1 Peptidase dimerisation domain JmjC PF02373.22 OQR89115.1 - 9.5e-08 32.5 0.1 4.1e-07 30.4 0.1 2.1 1 1 0 1 1 1 1 JmjC domain, hydroxylase Peptidase_M20 PF01546.28 OQR89115.1 - 2e-06 27.6 0.1 3e-06 27.1 0.1 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 BRE PF06113.12 OQR89115.1 - 0.072 11.9 0.1 0.44 9.3 0.0 2.1 2 0 0 2 2 2 0 Brain and reproductive organ-expressed protein (BRE) FYVE PF01363.21 OQR89116.1 - 3.7e-12 46.2 11.3 1.1e-11 44.7 11.3 1.8 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.16 OQR89116.1 - 0.0094 16.2 3.9 0.023 14.9 3.9 1.7 1 0 0 1 1 1 1 FYVE-type zinc finger HECT PF00632.25 OQR89117.1 - 9.8e-33 113.9 0.2 2.1e-30 106.3 0.2 2.8 1 1 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Pkinase_Tyr PF07714.17 OQR89125.1 - 5.6e-34 117.6 0.1 3.8e-19 69.0 0.0 3.0 2 1 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 OQR89125.1 - 2.3e-26 92.7 0.0 3.5e-15 56.1 0.0 2.3 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OQR89126.1 - 2.1e-20 73.1 0.1 3.7e-20 72.3 0.1 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OQR89126.1 - 4e-17 62.5 0.0 4.4e-17 62.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQR89127.1 - 4.3e-30 104.9 0.1 7.7e-30 104.0 0.1 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OQR89127.1 - 3.4e-25 88.9 0.0 5.4e-25 88.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain DUF809 PF05663.11 OQR89127.1 - 0.095 12.8 0.3 0.15 12.2 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF809) HTH_38 PF13936.6 OQR89129.1 - 0.057 13.2 0.4 0.18 11.6 0.4 1.9 1 1 0 1 1 1 0 Helix-turn-helix domain DUF2732 PF10809.8 OQR89129.1 - 0.1 12.4 0.2 0.14 12.0 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2732) UPF0242 PF06785.11 OQR89131.1 - 0.63 10.1 5.3 2.4 8.2 0.3 2.5 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus DUF4407 PF14362.6 OQR89131.1 - 0.75 9.1 12.7 0.64 9.3 6.5 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) PBP_N PF17093.5 OQR89131.1 - 5 7.4 6.6 0.31 11.3 0.3 2.1 2 1 1 3 3 3 0 Penicillin-binding protein N-terminus Hydrolase PF00702.26 OQR89132.1 - 0.00046 20.5 0.0 0.00068 20.0 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_C PF00689.21 OQR89132.1 - 0.063 13.0 9.8 0.15 11.7 6.9 2.3 1 1 1 2 2 2 0 Cation transporting ATPase, C-terminus bZIP_1 PF00170.21 OQR89133.1 - 0.0099 16.0 10.3 0.027 14.6 10.3 1.8 1 1 0 1 1 1 1 bZIP transcription factor Ank_2 PF12796.7 OQR89137.1 - 4.8e-32 110.4 7.7 4.2e-11 43.3 0.5 3.8 3 1 1 4 4 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQR89137.1 - 4.8e-29 100.3 2.5 8.4e-09 35.8 0.0 5.5 2 2 3 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQR89137.1 - 6.5e-25 84.5 1.8 0.014 15.9 0.0 7.6 7 0 0 7 7 7 5 Ankyrin repeat Ank PF00023.30 OQR89137.1 - 5.4e-24 83.5 7.6 0.0023 18.3 0.0 8.2 8 0 0 8 8 8 5 Ankyrin repeat Ank_5 PF13857.6 OQR89137.1 - 2.1e-21 75.7 2.7 6.2e-06 26.4 0.1 5.7 3 2 2 5 5 5 5 Ankyrin repeats (many copies) TPR_1 PF00515.28 OQR89137.1 - 5.6e-10 38.6 8.4 5.1e-05 22.9 0.2 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 OQR89137.1 - 1.8e-09 37.0 8.2 0.00065 19.6 0.1 3.9 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 OQR89137.1 - 2.6e-06 27.0 5.0 3.6e-06 26.6 0.8 2.4 2 0 0 2 2 2 1 TPR repeat TPR_16 PF13432.6 OQR89137.1 - 2.5e-05 24.8 3.0 0.078 13.6 0.1 2.8 1 1 1 2 2 2 2 Tetratricopeptide repeat ANAPC3 PF12895.7 OQR89137.1 - 0.00093 19.4 3.6 0.0024 18.1 3.6 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.6 OQR89137.1 - 0.0014 19.1 4.3 0.051 14.1 1.0 3.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 OQR89137.1 - 0.0095 16.1 0.9 3.9 7.9 0.1 3.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 OQR89137.1 - 0.012 15.8 5.6 3.4 8.0 1.7 3.0 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_17 PF13431.6 OQR89137.1 - 0.017 15.5 5.3 0.86 10.1 2.5 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_9 PF13371.6 OQR89137.1 - 0.023 14.8 0.2 0.087 13.0 0.2 2.1 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_14 PF13428.6 OQR89137.1 - 0.096 13.6 2.9 12 7.1 0.0 3.8 2 1 1 3 3 3 0 Tetratricopeptide repeat Pecanex_C PF05041.15 OQR89137.1 - 0.1 12.2 0.0 0.18 11.3 0.0 1.3 1 0 0 1 1 1 0 Pecanex protein (C-terminus) MIT PF04212.18 OQR89137.1 - 0.13 12.3 1.7 20 5.3 0.1 3.4 3 0 0 3 3 3 0 MIT (microtubule interacting and transport) domain Tim17 PF02466.19 OQR89139.1 - 6.3e-11 42.6 4.4 9.5e-11 42.1 4.4 1.3 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Beta-lactamase PF00144.24 OQR89140.1 - 1.3e-06 27.9 0.0 1.8e-06 27.4 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase DUF3471 PF11954.8 OQR89140.1 - 0.15 12.5 0.0 0.24 11.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3471) MatE PF01554.18 OQR89141.1 - 2.4e-31 108.6 33.3 1.5e-18 67.0 12.9 2.3 2 0 0 2 2 2 2 MatE Polysacc_synt_C PF14667.6 OQR89141.1 - 0.62 10.1 45.1 0.014 15.4 14.8 4.6 2 2 3 5 5 5 0 Polysaccharide biosynthesis C-terminal domain Mito_fiss_Elm1 PF06258.11 OQR89144.1 - 2.1e-59 201.2 0.0 2.4e-59 201.0 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial fission ELM1 Epimerase_2 PF02350.19 OQR89144.1 - 0.029 13.2 0.0 0.039 12.8 0.0 1.2 1 0 0 1 1 1 0 UDP-N-acetylglucosamine 2-epimerase RCC1 PF00415.18 OQR89145.1 - 9.7e-66 218.2 18.7 1.1e-15 57.9 0.3 8.1 8 0 0 8 8 8 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 OQR89145.1 - 1.3e-27 94.9 42.3 1.8e-05 24.4 1.4 7.7 7 1 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat HAGH_C PF16123.5 OQR89145.1 - 5.9e-24 84.4 0.1 1.1e-23 83.6 0.1 1.4 1 0 0 1 1 1 1 Hydroxyacylglutathione hydrolase C-terminus Lactamase_B PF00753.27 OQR89145.1 - 9.4e-15 55.1 1.4 2.6e-14 53.7 1.4 1.8 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 OQR89145.1 - 0.056 12.9 0.0 0.12 11.9 0.0 1.6 1 0 0 1 1 1 0 Beta-lactamase superfamily domain LRAT PF04970.13 OQR89151.1 - 2.2e-09 37.7 0.0 1.1e-08 35.5 0.0 2.0 1 1 0 1 1 1 1 Lecithin retinol acyltransferase COG5 PF10392.9 OQR89151.1 - 0.081 13.1 1.2 0.14 12.3 1.2 1.4 1 0 0 1 1 1 0 Golgi transport complex subunit 5 zf-RanBP PF00641.18 OQR89152.1 - 1.4e-14 53.1 15.4 1.9e-07 30.3 0.8 2.5 2 0 0 2 2 2 2 Zn-finger in Ran binding protein and others zf-RING_5 PF14634.6 OQR89152.1 - 0.037 14.0 3.2 0.12 12.3 3.2 1.9 1 1 0 1 1 1 0 zinc-RING finger domain zf-P11 PF03854.14 OQR89152.1 - 0.11 12.2 2.6 0.27 10.9 0.1 2.1 2 0 0 2 2 2 0 P-11 zinc finger RR_TM4-6 PF06459.12 OQR89152.1 - 0.91 9.3 8.1 1.1 9.1 8.1 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 RecR PF02132.15 OQR89152.1 - 8.2 6.1 11.2 0.2 11.3 2.0 2.6 2 1 0 2 2 2 0 RecR protein EST1_DNA_bind PF10373.9 OQR89153.1 - 3.2e-35 122.0 0.1 5.8e-35 121.1 0.1 1.4 1 0 0 1 1 1 1 Est1 DNA/RNA binding domain EST1 PF10374.9 OQR89153.1 - 3.2e-12 47.3 3.4 4e-10 40.4 1.9 2.9 2 1 0 2 2 2 1 Telomerase activating protein Est1 TPR_19 PF14559.6 OQR89153.1 - 0.11 13.0 1.6 23 5.6 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat Tubulin PF00091.25 OQR89154.1 - 5.7e-56 189.8 0.0 1.8e-55 188.2 0.0 1.8 1 1 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 OQR89154.1 - 3.7e-46 156.4 0.0 5.7e-46 155.8 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Pkinase_Tyr PF07714.17 OQR89156.1 - 2.1e-16 60.0 0.0 2.7e-16 59.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OQR89156.1 - 1.3e-12 47.6 0.0 1.7e-12 47.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pro_isomerase PF00160.21 OQR89157.1 - 1.3e-45 155.5 0.0 1.8e-45 155.1 0.0 1.2 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Lipoxygenase PF00305.19 OQR89159.1 - 6.6e-15 54.6 0.9 2.8e-14 52.5 0.9 1.9 1 1 0 1 1 1 1 Lipoxygenase SWIB PF02201.18 OQR89159.1 - 0.11 12.4 0.5 2.1 8.3 0.0 2.7 3 0 0 3 3 3 0 SWIB/MDM2 domain Thioredoxin_6 PF13848.6 OQR89161.1 - 6.1e-06 26.3 0.1 0.0051 16.7 0.0 4.1 2 1 1 3 3 3 1 Thioredoxin-like domain FCP1_C PF09309.10 OQR89161.1 - 0.04 13.8 11.5 0.19 11.5 10.6 2.0 2 0 0 2 2 2 0 FCP1, C-terminal Peptidase_S49_N PF08496.10 OQR89161.1 - 1.1 9.3 14.6 2.1 8.4 14.6 1.4 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Membralin PF09746.9 OQR89161.1 - 1.2 8.0 4.1 1.3 7.9 0.0 2.1 2 0 0 2 2 2 0 Tumour-associated protein EF-hand_7 PF13499.6 OQR89162.1 - 2.3e-48 162.5 12.1 6.2e-13 49.0 0.1 7.6 7 0 0 7 7 7 5 EF-hand domain pair EF-hand_1 PF00036.32 OQR89162.1 - 6.5e-44 144.2 6.0 4.3e-06 25.9 0.0 10.5 10 0 0 10 10 10 7 EF hand EF-hand_6 PF13405.6 OQR89162.1 - 3e-37 123.3 7.4 3.6e-06 26.5 0.1 10.3 10 0 0 10 10 10 7 EF-hand domain EF-hand_5 PF13202.6 OQR89162.1 - 3.3e-27 92.7 10.3 5.6e-05 22.4 0.1 8.2 8 0 0 8 8 8 7 EF hand EF-hand_8 PF13833.6 OQR89162.1 - 3.9e-23 81.1 16.0 1.7e-07 31.0 0.1 7.1 4 3 3 7 7 7 5 EF-hand domain pair WW PF00397.26 OQR89162.1 - 5.2e-19 68.0 20.8 1.8e-10 40.7 1.8 5.6 5 0 0 5 5 5 3 WW domain Ank_2 PF12796.7 OQR89162.1 - 7.9e-17 61.6 1.1 5.7e-05 23.6 0.2 5.2 1 1 3 5 5 5 5 Ankyrin repeats (3 copies) SPARC_Ca_bdg PF10591.9 OQR89162.1 - 1.7e-10 41.2 11.1 0.0096 16.2 0.1 5.5 4 1 1 5 5 5 3 Secreted protein acidic and rich in cysteine Ca binding region Ank_5 PF13857.6 OQR89162.1 - 2.8e-09 37.0 6.7 0.15 12.4 0.6 5.9 3 1 2 5 5 5 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQR89162.1 - 4.2e-09 35.9 15.4 0.75 10.5 0.1 8.9 8 1 1 9 9 7 2 Ankyrin repeat EF-hand_9 PF14658.6 OQR89162.1 - 3.7e-08 33.6 0.3 1.2 9.5 0.0 6.0 6 0 0 6 6 6 3 EF-hand domain Ank_4 PF13637.6 OQR89162.1 - 8.9e-08 32.5 8.1 0.00039 20.9 0.3 5.6 4 1 0 5 5 5 1 Ankyrin repeats (many copies) Ank PF00023.30 OQR89162.1 - 5.1e-06 26.7 17.4 3.1 8.4 0.1 7.9 8 0 0 8 8 8 2 Ankyrin repeat EF-hand_10 PF14788.6 OQR89162.1 - 8.8e-05 22.3 0.0 1.7 8.6 0.0 4.9 5 0 0 5 5 4 1 EF hand EF-hand_11 PF08976.11 OQR89162.1 - 0.0041 18.0 0.9 5.3 8.0 0.0 3.6 3 1 0 3 3 2 1 EF-hand domain DUF5580 PF17743.1 OQR89162.1 - 0.0051 15.4 0.1 0.013 14.0 0.1 1.6 1 0 0 1 1 1 1 Family of unknown function (DUF5580) DXP_synthase_N PF13292.6 OQR89162.1 - 0.0067 15.7 0.0 0.37 10.0 0.0 3.1 3 1 0 3 3 3 1 1-deoxy-D-xylulose-5-phosphate synthase EF-hand_4 PF12763.7 OQR89162.1 - 0.15 12.0 12.2 11 6.1 0.1 6.0 4 1 2 6 6 6 0 Cytoskeletal-regulatory complex EF hand IQ PF00612.27 OQR89162.1 - 0.24 11.3 2.7 1.2 9.2 2.7 2.2 1 0 0 1 1 1 0 IQ calmodulin-binding motif Fe_dep_repr_C PF02742.15 OQR89162.1 - 0.45 10.6 1.9 22 5.2 0.1 3.5 3 0 0 3 3 3 0 Iron dependent repressor, metal binding and dimerisation domain EF-hand_14 PF17959.1 OQR89162.1 - 0.47 10.8 2.8 29 5.1 0.0 3.6 4 0 0 4 4 3 0 EF-hand domain PDEase_I PF00233.19 OQR89163.1 - 1.3e-66 224.8 4.7 1.3e-66 224.7 2.6 2.1 2 0 0 2 2 2 1 3'5'-cyclic nucleotide phosphodiesterase ApbA_C PF08546.11 OQR89163.1 - 0.14 12.4 0.5 12 6.1 0.5 2.6 1 1 0 1 1 1 0 Ketopantoate reductase PanE/ApbA C terminal Hydrophobin_2 PF06766.11 OQR89163.1 - 0.68 9.9 2.4 40 4.3 0.9 3.2 3 0 0 3 3 3 0 Fungal hydrophobin p450 PF00067.22 OQR89164.1 - 0.05 12.3 0.0 0.057 12.1 0.0 1.0 1 0 0 1 1 1 0 Cytochrome P450 p450 PF00067.22 OQR89165.1 - 4.9e-05 22.3 0.0 5.5e-05 22.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 EpuA PF11772.8 OQR89165.1 - 1.1 9.0 3.1 6.7 6.5 0.0 2.5 2 0 0 2 2 2 0 DNA-directed RNA polymerase subunit beta Acyl_transf_1 PF00698.21 OQR89166.1 - 6.6e-18 65.3 2.9 9.1e-18 64.8 2.9 1.1 1 0 0 1 1 1 1 Acyl transferase domain p450 PF00067.22 OQR89166.1 - 6.6e-12 44.9 0.0 1.4e-11 43.9 0.0 1.5 2 0 0 2 2 2 1 Cytochrome P450 SAT PF16073.5 OQR89166.1 - 0.021 14.6 0.6 0.08 12.7 0.5 1.8 1 1 0 1 1 1 0 Starter unit:ACP transacylase in aflatoxin biosynthesis DNA_ligase_A_M PF01068.21 OQR89169.1 - 7.5e-40 136.8 0.0 1.2e-39 136.1 0.0 1.4 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_C PF04679.15 OQR89169.1 - 3e-23 82.3 0.0 6.3e-23 81.2 0.0 1.6 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region DNA_ligase_A_N PF04675.14 OQR89169.1 - 1.6e-22 80.7 0.9 3.6e-22 79.5 0.6 1.7 2 0 0 2 2 2 1 DNA ligase N terminus RNA_ligase PF09414.10 OQR89169.1 - 2e-07 31.4 0.0 3.6e-07 30.7 0.0 1.3 1 0 0 1 1 1 1 RNA ligase mRNA_cap_enzyme PF01331.19 OQR89169.1 - 0.00032 20.6 0.0 0.0018 18.1 0.0 2.1 1 1 0 1 1 1 1 mRNA capping enzyme, catalytic domain DNA_ligase_OB_2 PF14743.6 OQR89169.1 - 0.0026 17.8 0.1 1 9.5 0.0 3.2 4 0 0 4 4 4 1 DNA ligase OB-like domain RMP PF14996.6 OQR89170.1 - 2.2e-41 141.6 5.2 2.6e-41 141.4 5.2 1.1 1 0 0 1 1 1 1 Retinal Maintenance Pet191_N PF10203.9 OQR89171.1 - 4.1e-16 59.0 3.2 4.5e-16 58.9 3.2 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein PET191 cNMP_binding PF00027.29 OQR89172.1 - 9.6e-11 41.6 0.0 1.4e-09 37.9 0.0 2.5 2 1 0 2 2 2 1 Cyclic nucleotide-binding domain Pkinase_Tyr PF07714.17 OQR89173.1 - 2.1e-19 69.9 0.0 1.4e-12 47.4 0.0 2.5 2 1 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 OQR89173.1 - 5e-17 62.1 0.0 4.7e-08 32.7 0.0 2.5 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 OQR89175.1 - 2.2e-23 82.9 0.0 2.8e-23 82.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OQR89175.1 - 6.8e-22 78.1 0.0 1.1e-21 77.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Kinesin PF00225.23 OQR89178.1 - 2.8e-104 348.6 3.5 2.8e-104 348.6 3.5 2.4 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 OQR89178.1 - 1.1e-47 161.7 2.8 2.1e-47 160.8 0.1 2.8 2 0 0 2 2 2 1 Microtubule binding AAA_22 PF13401.6 OQR89179.1 - 0.091 13.0 0.0 0.33 11.2 0.0 1.9 2 0 0 2 2 2 0 AAA domain XPG_N PF00752.17 OQR89181.1 - 5e-20 71.9 0.0 1.5e-19 70.3 0.0 1.9 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.18 OQR89181.1 - 2.1e-13 50.4 0.2 1e-12 48.2 0.1 2.4 2 0 0 2 2 2 1 XPG I-region XPG_I_2 PF12813.7 OQR89181.1 - 3.3e-05 23.5 0.1 7e-05 22.4 0.1 1.5 1 0 0 1 1 1 1 XPG domain containing ClpB_D2-small PF10431.9 OQR89182.1 - 6.1e-23 80.7 0.3 7.6e-23 80.4 0.3 1.1 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein ThiF PF00899.21 OQR89182.1 - 0.17 11.2 0.0 0.2 11.0 0.0 1.1 1 0 0 1 1 1 0 ThiF family Pkinase PF00069.25 OQR89185.1 - 2e-53 181.4 0.0 4e-35 121.5 0.1 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OQR89185.1 - 7.6e-29 100.8 0.0 4.6e-23 81.8 0.1 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase RGS PF00615.19 OQR89185.1 - 1.6e-11 44.5 0.3 1.6e-11 44.5 0.3 1.8 2 0 0 2 2 2 1 Regulator of G protein signaling domain Kinase-like PF14531.6 OQR89185.1 - 2e-07 30.6 0.0 0.00049 19.5 0.0 2.3 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.14 OQR89185.1 - 0.00066 19.1 0.0 0.0017 17.8 0.0 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_Tyr PF07714.17 OQR89186.1 - 3.2e-52 177.4 0.0 4.6e-52 176.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OQR89186.1 - 2.3e-50 171.4 0.0 3.5e-50 170.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Ank_2 PF12796.7 OQR89186.1 - 2.2e-30 105.1 7.4 1.2e-14 54.7 0.3 4.3 4 1 1 5 5 5 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQR89186.1 - 1.4e-21 76.5 1.8 2.5e-05 24.7 0.1 5.4 2 2 3 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQR89186.1 - 1.7e-21 74.0 4.1 0.0011 19.2 0.1 7.7 9 0 0 9 9 9 4 Ankyrin repeat Ank_5 PF13857.6 OQR89186.1 - 1.1e-20 73.5 10.2 1.5e-06 28.3 0.4 6.1 2 1 5 7 7 7 5 Ankyrin repeats (many copies) Ank PF00023.30 OQR89186.1 - 1.6e-18 66.2 15.5 0.00056 20.2 0.1 7.0 6 2 1 7 7 7 5 Ankyrin repeat Haspin_kinase PF12330.8 OQR89186.1 - 0.0012 17.9 0.1 0.012 14.6 0.1 2.1 1 1 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 OQR89186.1 - 0.0041 16.5 0.0 0.0064 15.9 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family NDUF_C2 PF06374.11 OQR89188.1 - 0.12 12.6 0.0 0.23 11.6 0.0 1.4 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase subunit b14.5b (NDUFC2) SVA PF05326.11 OQR89188.1 - 0.16 12.0 3.6 2.2 8.3 1.6 2.3 2 0 0 2 2 2 0 Seminal vesicle autoantigen (SVA) Oxidored_FMN PF00724.20 OQR89192.1 - 4.1e-81 272.9 0.0 4.9e-81 272.7 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Peptidase_S28 PF05577.12 OQR89194.1 - 2.6e-96 323.1 2.6 3.1e-96 322.8 2.6 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase S28 Peptidase_S37 PF05576.11 OQR89194.1 - 0.00012 20.9 0.1 0.00019 20.3 0.1 1.3 1 0 0 1 1 1 1 PS-10 peptidase S37 Abhydrolase_1 PF00561.20 OQR89194.1 - 0.042 13.5 0.0 0.12 12.0 0.0 1.8 2 0 0 2 2 2 0 alpha/beta hydrolase fold Mannosyl_trans3 PF11051.8 OQR89195.1 - 1.3e-37 129.6 0.0 2e-37 129.0 0.0 1.2 1 0 0 1 1 1 1 Mannosyltransferase putative ABC_membrane PF00664.23 OQR89197.1 - 7.6e-26 91.4 14.0 1.1e-25 90.9 14.0 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_membrane PF00664.23 OQR89198.1 - 1.2e-54 185.8 39.9 8.3e-28 97.8 22.6 2.3 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 OQR89198.1 - 2.3e-21 76.7 0.0 4.2e-21 75.9 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_16 PF13191.6 OQR89198.1 - 0.02 15.3 0.0 0.043 14.2 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain RsgA_GTPase PF03193.16 OQR89198.1 - 0.095 12.6 0.0 0.21 11.5 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase Ank_4 PF13637.6 OQR89202.1 - 1.6e-17 63.6 1.6 2.4e-12 47.1 0.1 2.9 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 OQR89202.1 - 2.6e-15 56.8 2.5 1.9e-09 38.0 0.4 2.8 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank PF00023.30 OQR89202.1 - 1.8e-13 50.2 4.9 4.6e-06 26.8 0.1 4.0 4 0 0 4 4 4 3 Ankyrin repeat Ank_3 PF13606.6 OQR89202.1 - 1.6e-12 46.4 0.9 2.7e-05 24.2 0.0 3.8 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.6 OQR89202.1 - 1.3e-09 38.1 1.9 4.9e-06 26.7 0.7 3.5 1 1 2 3 3 3 2 Ankyrin repeats (many copies) WW PF00397.26 OQR89202.1 - 0.00035 20.6 1.7 0.00035 20.6 1.7 2.6 2 0 0 2 2 2 1 WW domain Spc7 PF08317.11 OQR89203.1 - 0.0015 17.5 17.4 0.0015 17.5 17.4 3.9 1 1 2 4 4 4 2 Spc7 kinetochore protein YusW PF14039.6 OQR89203.1 - 0.52 10.9 7.8 3.3 8.3 0.0 3.9 3 0 0 3 3 3 0 YusW-like protein TSC22 PF01166.18 OQR89203.1 - 1.5 9.2 15.1 0.069 13.5 4.7 3.9 3 1 1 4 4 4 0 TSC-22/dip/bun family NAD_binding_6 PF08030.12 OQR89204.1 - 8.5e-14 52.0 0.0 1.5e-10 41.4 0.0 2.4 2 0 0 2 2 2 2 Ferric reductase NAD binding domain NAD_binding_1 PF00175.21 OQR89204.1 - 7.7e-11 42.6 0.0 2.2e-10 41.1 0.0 1.8 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_8 PF08022.12 OQR89204.1 - 1.8e-10 40.9 0.0 3.1e-10 40.1 0.0 1.3 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.12 OQR89205.1 - 1.2e-14 54.7 0.1 2.5e-12 47.2 0.1 2.3 1 1 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 OQR89205.1 - 9e-11 41.8 0.0 1.7e-10 41.0 0.0 1.4 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_1 PF00175.21 OQR89205.1 - 2.1e-06 28.4 0.0 3.4e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Ferric_reduct PF01794.19 OQR89205.1 - 4e-05 23.7 0.5 8.7e-05 22.6 0.5 1.6 1 0 0 1 1 1 1 Ferric reductase like transmembrane component NTP_transferase PF00483.23 OQR89211.1 - 2.8e-22 79.5 0.0 4.4e-22 78.9 0.0 1.5 1 1 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.7 OQR89211.1 - 4.5e-12 46.6 0.0 5.1e-12 46.4 0.0 1.3 1 0 0 1 1 1 1 MobA-like NTP transferase domain IspD PF01128.19 OQR89211.1 - 0.0016 18.2 0.0 0.0024 17.7 0.0 1.3 1 0 0 1 1 1 1 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase DUF5612 PF18462.1 OQR89211.1 - 0.01 15.7 0.1 0.019 14.8 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5612) KASH_CCD PF14662.6 OQR89212.1 - 0.022 14.6 5.3 0.035 13.9 5.3 1.3 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH SIKE PF05769.11 OQR89212.1 - 0.069 13.1 4.4 0.12 12.3 4.4 1.3 1 0 0 1 1 1 0 SIKE family DUF2383 PF09537.10 OQR89212.1 - 0.078 13.3 2.4 2.3 8.6 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF2383) Lipoprotein_7 PF01540.16 OQR89212.1 - 0.31 10.3 3.3 0.45 9.8 3.3 1.1 1 0 0 1 1 1 0 Adhesin lipoprotein bZIP_1 PF00170.21 OQR89212.1 - 0.43 10.7 15.0 0.46 10.6 7.5 2.3 2 0 0 2 2 2 0 bZIP transcription factor ATG16 PF08614.11 OQR89212.1 - 1.3 9.2 18.7 26 5.0 18.7 2.1 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) AAA_13 PF13166.6 OQR89212.1 - 1.5 7.4 7.6 3 6.4 7.6 1.3 1 1 0 1 1 1 0 AAA domain SlyX PF04102.12 OQR89212.1 - 1.7 9.3 6.2 2.1 9.1 3.5 2.3 2 0 0 2 2 2 0 SlyX FAM76 PF16046.5 OQR89212.1 - 1.7 7.9 9.0 2.5 7.4 9.0 1.2 1 0 0 1 1 1 0 FAM76 protein Ndc1_Nup PF09531.10 OQR89212.1 - 2.1 6.9 6.2 2.7 6.6 6.2 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup BLOC1_2 PF10046.9 OQR89212.1 - 2.2 8.6 4.9 22 5.4 0.3 2.4 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 bZIP_2 PF07716.15 OQR89212.1 - 2.7 8.1 21.6 0.058 13.5 10.6 2.3 2 0 0 2 2 2 0 Basic region leucine zipper ADIP PF11559.8 OQR89212.1 - 3.8 7.6 10.8 3.7 7.6 1.3 2.2 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding HOOK PF05622.12 OQR89212.1 - 3.8 5.5 13.5 5.3 5.1 13.5 1.1 1 0 0 1 1 1 0 HOOK protein DHHC PF01529.20 OQR89215.1 - 1.9e-07 31.2 9.3 1.9e-07 31.2 9.3 2.1 2 0 0 2 2 2 1 DHHC palmitoyltransferase Mannosyl_trans3 PF11051.8 OQR89217.1 - 1e-32 113.6 0.5 2.5e-28 99.2 0.8 2.9 2 1 0 2 2 2 2 Mannosyltransferase putative Ank_5 PF13857.6 OQR89221.1 - 1.3e-13 50.9 0.4 8.4e-13 48.3 0.5 2.0 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 OQR89221.1 - 4.4e-13 49.5 0.4 7e-07 29.7 0.1 3.0 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 OQR89221.1 - 2.7e-12 46.6 1.9 4.6e-05 23.7 0.3 3.1 3 0 0 3 3 3 2 Ankyrin repeat Ank_2 PF12796.7 OQR89221.1 - 2.8e-12 47.0 0.1 4.7e-12 46.3 0.1 1.4 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OQR89221.1 - 5e-10 38.7 0.2 1.5e-05 25.0 0.1 3.0 3 0 0 3 3 3 2 Ankyrin repeat Raptor_N PF14538.6 OQR89222.1 - 4.4e-69 231.1 0.0 6.1e-69 230.6 0.0 1.2 1 0 0 1 1 1 1 Raptor N-terminal CASPase like domain Peptidase_C14 PF00656.22 OQR89222.1 - 0.02 14.9 0.0 0.031 14.2 0.0 1.3 1 1 0 1 1 1 0 Caspase domain Peptidase_C1 PF00112.23 OQR89227.1 - 5e-76 255.6 12.6 3.8e-40 138.3 4.5 3.6 2 2 0 2 2 2 2 Papain family cysteine protease Peptidase_C1_2 PF03051.15 OQR89227.1 - 6.6e-06 25.2 7.9 0.15 10.8 0.1 4.0 4 0 0 4 4 4 3 Peptidase C1-like family Peptidase_C39_2 PF13529.6 OQR89227.1 - 0.0066 17.0 5.5 0.11 13.0 0.1 2.7 2 1 0 2 2 2 1 Peptidase_C39 like family AAA_6 PF12774.7 OQR89228.1 - 1.1e-121 405.8 0.0 2.4e-121 404.7 0.0 1.5 1 0 0 1 1 1 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 OQR89228.1 - 4.1e-92 309.4 0.2 4.1e-92 309.4 0.2 2.5 3 0 0 3 3 3 1 Dynein heavy chain, N-terminal region 2 Kelch_5 PF13854.6 OQR89228.1 - 1.1e-41 140.2 1.0 1.7e-06 27.9 0.0 6.6 6 0 0 6 6 6 6 Kelch motif Kelch_4 PF13418.6 OQR89228.1 - 8.9e-32 108.9 2.0 1.1e-06 28.5 0.0 6.7 6 0 0 6 6 6 4 Galactose oxidase, central domain Kelch_3 PF13415.6 OQR89228.1 - 2.9e-28 97.5 4.5 4e-10 39.7 0.0 7.0 7 0 0 7 7 7 5 Galactose oxidase, central domain Kelch_1 PF01344.25 OQR89228.1 - 1.4e-24 85.4 7.6 4.4e-07 29.4 0.0 6.2 6 1 1 7 7 7 3 Kelch motif Kelch_6 PF13964.6 OQR89228.1 - 3.5e-24 84.2 10.5 2.2e-06 27.8 0.0 6.3 3 2 3 6 6 6 5 Kelch motif Kelch_2 PF07646.15 OQR89228.1 - 1.5e-20 72.3 10.5 4.6e-07 29.6 0.2 6.4 6 0 0 6 6 6 4 Kelch motif TIG PF01833.24 OQR89228.1 - 0.00082 19.4 0.9 0.0045 17.0 1.1 2.0 2 0 0 2 2 2 1 IPT/TIG domain AAA_5 PF07728.14 OQR89228.1 - 0.03 14.3 0.0 0.17 11.9 0.0 2.3 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) DUF4208 PF13907.6 OQR89228.1 - 0.044 14.2 0.5 0.26 11.7 0.1 2.6 2 0 0 2 2 1 0 Domain of unknown function (DUF4208) AAA PF00004.29 OQR89228.1 - 0.088 13.2 0.0 0.38 11.2 0.0 2.1 2 0 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) Seryl_tRNA_N PF02403.22 OQR89228.1 - 0.14 12.4 1.1 8.2 6.7 0.9 3.1 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DUF1848 PF08902.11 OQR89228.1 - 0.2 11.3 0.9 1.7 8.3 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1848) Fez1 PF06818.15 OQR89228.1 - 9.4 6.6 11.3 6.6 7.1 8.0 2.1 2 0 0 2 2 2 0 Fez1 Amino_oxidase PF01593.24 OQR89229.1 - 1.8e-15 57.2 0.0 9.1e-10 38.4 0.0 2.1 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 OQR89229.1 - 2.3e-15 56.6 0.0 4.9e-15 55.5 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 OQR89229.1 - 3.5e-10 39.6 0.3 2.4e-06 27.0 0.3 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 OQR89229.1 - 1.2e-09 38.2 0.4 6.5e-07 29.2 0.6 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 OQR89229.1 - 2.8e-07 30.0 0.1 5e-07 29.2 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 OQR89229.1 - 6.2e-07 29.1 0.1 1.1e-06 28.3 0.1 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 OQR89229.1 - 1.1e-06 28.7 0.0 0.038 14.0 0.0 2.5 2 0 0 2 2 2 2 FAD-NAD(P)-binding HI0933_like PF03486.14 OQR89229.1 - 5.5e-05 22.0 0.7 0.0058 15.4 0.1 2.1 2 0 0 2 2 2 2 HI0933-like protein Thi4 PF01946.17 OQR89229.1 - 0.00016 21.0 0.0 0.00025 20.4 0.0 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox PF00070.27 OQR89229.1 - 0.00053 20.5 0.4 0.047 14.3 0.4 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 OQR89229.1 - 0.0015 17.7 1.5 0.0034 16.5 0.2 2.0 2 0 0 2 2 2 1 Glucose inhibited division protein A O-FucT PF10250.9 OQR89229.1 - 0.012 15.4 0.1 0.024 14.4 0.0 1.3 1 1 0 1 1 1 0 GDP-fucose protein O-fucosyltransferase Pyr_redox_3 PF13738.6 OQR89229.1 - 0.02 14.1 1.5 0.18 11.0 0.3 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.16 OQR89229.1 - 0.025 14.2 0.2 0.059 13.0 0.2 1.6 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Trp_halogenase PF04820.14 OQR89229.1 - 0.032 13.1 0.1 2.7 6.8 0.1 2.2 2 0 0 2 2 2 0 Tryptophan halogenase Lycopene_cycl PF05834.12 OQR89229.1 - 0.068 12.2 5.7 1.9 7.5 0.3 2.6 2 1 0 3 3 3 0 Lycopene cyclase protein UDPG_MGDP_dh_N PF03721.14 OQR89229.1 - 0.094 12.3 0.2 0.17 11.5 0.2 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain FAD_binding_3 PF01494.19 OQR89229.1 - 0.1 11.9 0.4 0.3 10.3 0.1 1.8 2 0 0 2 2 2 0 FAD binding domain 3HCDH_N PF02737.18 OQR89229.1 - 0.18 11.6 0.2 0.3 10.9 0.2 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Methyltransf_16 PF10294.9 OQR89230.1 - 6.3e-13 48.8 0.0 6.1e-12 45.6 0.0 2.2 2 0 0 2 2 2 1 Lysine methyltransferase SET PF00856.28 OQR89230.1 - 3.6e-08 34.0 0.0 7.3e-08 33.0 0.0 1.5 1 0 0 1 1 1 1 SET domain Methyltransf_25 PF13649.6 OQR89230.1 - 5.1e-08 33.5 0.0 1.3e-07 32.2 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OQR89230.1 - 1.9e-07 31.1 0.0 4.8e-07 29.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OQR89230.1 - 3.3e-06 27.0 0.0 6.1e-06 26.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OQR89230.1 - 9e-06 26.3 0.0 2.1e-05 25.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OQR89230.1 - 2.4e-05 25.0 0.0 5.6e-05 23.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 OQR89230.1 - 0.062 12.8 0.0 0.14 11.7 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase small domain KIX_2 PF16987.5 OQR89231.1 - 8.2e-05 22.5 0.2 0.00028 20.8 0.2 1.9 1 0 0 1 1 1 1 KIX domain BBP1_C PF15272.6 OQR89231.1 - 0.67 9.8 5.7 1.2 8.9 0.3 2.7 3 0 0 3 3 3 0 Spindle pole body component BBP1, C-terminal UQ_con PF00179.26 OQR89233.1 - 6.5e-46 155.5 0.0 1.3e-45 154.4 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme PfkB PF00294.24 OQR89233.1 - 1.2e-40 139.7 0.0 1.8e-40 139.1 0.0 1.1 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Prok-E2_B PF14461.6 OQR89233.1 - 0.0033 17.1 0.0 0.051 13.3 0.0 2.3 2 0 0 2 2 2 1 Prokaryotic E2 family B Phos_pyr_kin PF08543.12 OQR89233.1 - 0.0073 15.7 0.0 0.017 14.5 0.0 1.5 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase DUF1479 PF07350.12 OQR89233.1 - 0.017 13.9 0.0 0.031 13.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1479) Na_sulph_symp PF00939.19 OQR89234.1 - 8.1e-32 110.9 37.4 1.1e-31 110.5 37.4 1.1 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CitMHS PF03600.16 OQR89234.1 - 1.4e-29 103.3 31.2 1.4e-29 103.3 31.2 2.1 1 1 1 2 2 2 2 Citrate transporter SPX PF03105.19 OQR89234.1 - 1.2e-26 94.5 10.1 4.2e-13 50.0 4.2 2.8 1 1 2 3 3 3 3 SPX domain DUF2568 PF10823.8 OQR89234.1 - 0.02 15.1 0.7 0.02 15.1 0.7 3.2 4 0 0 4 4 4 0 Protein of unknown function (DUF2568) SafA PF17073.5 OQR89234.1 - 7 6.7 9.0 0.2 11.6 0.7 2.7 2 0 0 2 2 2 0 Two-component-system connector protein TEP1_N PF05386.11 OQR89234.1 - 8.9 6.0 8.4 3 7.5 0.0 2.8 3 0 0 3 3 3 0 TEP1 N-terminal domain IF-2B PF01008.17 OQR89235.1 - 1.5e-68 231.1 1.1 3.5e-68 229.9 1.1 1.5 1 1 0 1 1 1 1 Initiation factor 2 subunit family WD40 PF00400.32 OQR89236.1 - 1.1e-18 67.2 11.3 0.00016 22.3 0.1 6.9 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OQR89236.1 - 8.7e-06 26.0 0.5 0.0057 16.9 0.1 3.2 2 1 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 OQR89236.1 - 0.004 15.9 1.1 0.25 10.0 0.0 2.2 2 0 0 2 2 2 2 Nucleoporin Nup120/160 MRP-L28 PF09812.9 OQR89238.1 - 4.5e-05 23.6 0.1 9e-05 22.7 0.1 1.3 1 1 0 1 1 1 1 Mitochondrial ribosomal protein L28 DEAD PF00270.29 OQR89239.1 - 9.3e-27 93.9 0.1 9.3e-27 93.9 0.1 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Ank_5 PF13857.6 OQR89239.1 - 7.1e-15 54.9 2.8 1.4e-09 38.0 0.3 2.7 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 OQR89239.1 - 1.5e-11 44.7 0.1 9e-11 42.2 0.2 2.1 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) IQ PF00612.27 OQR89239.1 - 3.8e-10 38.7 10.2 0.0062 16.2 0.2 4.1 4 0 0 4 4 4 3 IQ calmodulin-binding motif Ank_3 PF13606.6 OQR89239.1 - 8.4e-09 35.0 1.3 0.0007 19.9 0.0 3.0 3 0 0 3 3 2 2 Ankyrin repeat Ank_4 PF13637.6 OQR89239.1 - 8.8e-08 32.5 0.8 6.5e-07 29.8 0.3 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 OQR89239.1 - 2.6e-07 30.8 1.7 0.001 19.4 0.1 3.1 2 0 0 2 2 2 2 Ankyrin repeat ResIII PF04851.15 OQR89239.1 - 4.5e-06 26.8 0.2 1.4e-05 25.2 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 OQR89239.1 - 0.0046 17.2 0.4 0.018 15.3 0.0 2.1 3 0 0 3 3 3 1 AAA domain SWI2_SNF2 PF18766.1 OQR89239.1 - 0.02 14.5 0.2 0.12 12.1 0.0 2.0 2 0 0 2 2 2 0 SWI2/SNF2 ATPase HHH_5 PF14520.6 OQR89239.1 - 0.21 12.2 1.4 6.8 7.4 0.1 2.9 2 0 0 2 2 2 0 Helix-hairpin-helix domain SBF_like PF13593.6 OQR89240.1 - 0.0089 15.4 0.3 0.011 15.1 0.3 1.1 1 0 0 1 1 1 1 SBF-like CPA transporter family (DUF4137) Claudin_3 PF06653.11 OQR89240.1 - 0.06 13.3 0.6 0.073 13.0 0.6 1.3 1 0 0 1 1 1 0 Tight junction protein, Claudin-like ABC2_membrane PF01061.24 OQR89249.1 - 1.8e-68 230.1 67.3 9.7e-37 126.4 27.3 3.0 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.27 OQR89249.1 - 3e-25 89.3 0.1 4.7e-13 49.8 0.0 3.3 2 1 0 2 2 2 2 ABC transporter AAA_29 PF13555.6 OQR89249.1 - 2.2e-07 30.5 2.8 0.014 15.1 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 OQR89249.1 - 4.6e-07 30.4 0.0 0.0019 18.6 0.0 2.3 2 0 0 2 2 2 2 AAA ATPase domain PDR_assoc PF08370.11 OQR89249.1 - 5.2e-07 29.3 0.8 5.2e-07 29.3 0.8 4.9 4 0 0 4 4 3 2 Plant PDR ABC transporter associated AAA_21 PF13304.6 OQR89249.1 - 7.3e-07 29.3 2.4 0.011 15.6 0.0 3.6 3 1 0 4 4 3 2 AAA domain, putative AbiEii toxin, Type IV TA system PDR_CDR PF06422.12 OQR89249.1 - 1.1e-06 28.4 2.2 5.8e-05 22.9 0.3 3.3 3 0 0 3 3 2 1 CDR ABC transporter RsgA_GTPase PF03193.16 OQR89249.1 - 2.3e-06 27.6 1.5 0.0099 15.8 0.3 2.3 2 0 0 2 2 2 2 RsgA GTPase AAA_22 PF13401.6 OQR89249.1 - 3.2e-06 27.5 0.2 0.0073 16.6 0.0 2.5 2 0 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.23 OQR89249.1 - 7.6e-05 22.8 0.1 0.045 13.8 0.0 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_30 PF13604.6 OQR89249.1 - 0.00016 21.5 0.3 0.24 11.1 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.6 OQR89249.1 - 0.00029 20.5 0.1 0.52 9.8 0.2 2.5 2 0 0 2 2 2 2 AAA domain AAA PF00004.29 OQR89249.1 - 0.0004 20.8 0.3 0.35 11.3 0.0 2.8 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_23 PF13476.6 OQR89249.1 - 0.00046 20.7 2.1 0.55 10.7 0.3 2.7 2 1 1 3 3 2 2 AAA domain ABC2_membrane_3 PF12698.7 OQR89249.1 - 0.00061 19.0 52.3 0.0056 15.8 23.4 3.2 2 2 0 2 2 2 2 ABC-2 family transporter protein NACHT PF05729.12 OQR89249.1 - 0.00084 19.3 1.1 0.37 10.7 0.1 2.5 2 0 0 2 2 2 1 NACHT domain cobW PF02492.19 OQR89249.1 - 0.0009 18.9 1.3 0.79 9.3 0.2 2.3 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain AAA_18 PF13238.6 OQR89249.1 - 0.001 19.6 0.0 0.25 11.9 0.0 2.4 2 0 0 2 2 2 1 AAA domain Ploopntkinase3 PF18751.1 OQR89249.1 - 0.0013 18.7 0.2 0.018 15.0 0.0 2.2 2 0 0 2 2 2 1 P-loop Nucleotide Kinase3 NTPase_1 PF03266.15 OQR89249.1 - 0.0013 18.7 4.4 0.01 15.8 0.1 3.1 3 0 0 3 3 3 1 NTPase SMC_N PF02463.19 OQR89249.1 - 0.0013 18.2 0.6 12 5.3 0.0 4.0 4 0 0 4 4 4 0 RecF/RecN/SMC N terminal domain RNA_helicase PF00910.22 OQR89249.1 - 0.0014 19.0 0.4 0.19 12.1 0.0 2.6 2 0 0 2 2 2 1 RNA helicase DUF87 PF01935.17 OQR89249.1 - 0.0017 18.5 4.6 0.023 14.8 0.1 2.5 2 0 0 2 2 2 1 Helicase HerA, central domain AAA_33 PF13671.6 OQR89249.1 - 0.0018 18.4 0.4 0.8 9.9 0.1 2.4 2 0 0 2 2 2 1 AAA domain ABC_ATPase PF09818.9 OQR89249.1 - 0.0051 15.7 0.7 0.23 10.2 0.1 2.2 2 0 0 2 2 2 1 Predicted ATPase of the ABC class Roc PF08477.13 OQR89249.1 - 0.0075 16.5 0.5 0.66 10.2 0.0 2.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase AAA_19 PF13245.6 OQR89249.1 - 0.0077 16.6 0.1 2.1 8.7 0.0 2.4 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 OQR89249.1 - 0.011 15.1 2.9 0.27 10.5 0.0 2.2 2 0 0 2 2 2 0 Zeta toxin AAA_17 PF13207.6 OQR89249.1 - 0.011 16.2 1.6 0.074 13.5 0.1 2.2 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.14 OQR89249.1 - 0.016 15.2 0.3 0.43 10.6 0.1 2.4 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) ATPase_2 PF01637.18 OQR89249.1 - 0.032 14.1 0.1 1.4 8.8 0.0 2.3 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea Rad17 PF03215.15 OQR89249.1 - 0.045 13.7 0.1 2.7 7.9 0.0 2.3 2 0 0 2 2 2 0 Rad17 P-loop domain RuvB_N PF05496.12 OQR89249.1 - 0.048 13.4 0.3 3.6 7.3 0.0 2.4 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain DUF2075 PF09848.9 OQR89249.1 - 0.05 12.8 0.0 0.17 11.1 0.0 1.8 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_24 PF13479.6 OQR89249.1 - 0.063 13.0 1.3 9.1 5.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 OQR89249.1 - 0.072 13.1 1.2 5.9 6.9 0.3 2.4 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE MCM PF00493.23 OQR89249.1 - 0.076 12.1 0.1 0.18 10.9 0.0 1.6 2 0 0 2 2 1 0 MCM P-loop domain ATP_bind_1 PF03029.17 OQR89249.1 - 0.11 12.3 1.4 0.56 9.9 0.0 2.2 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein PRK PF00485.18 OQR89249.1 - 0.13 11.9 0.1 5.9 6.6 0.1 2.3 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family Septin PF00735.18 OQR89249.1 - 0.14 11.4 0.2 2.3 7.4 0.0 2.1 2 0 0 2 2 2 0 Septin NB-ARC PF00931.22 OQR89249.1 - 0.2 10.8 2.1 8.1 5.6 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain Gtr1_RagA PF04670.12 OQR89249.1 - 0.21 10.9 0.6 13 5.0 0.0 2.3 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region Viral_helicase1 PF01443.18 OQR89249.1 - 0.25 11.0 0.2 1.7 8.4 0.0 2.5 3 0 0 3 3 3 0 Viral (Superfamily 1) RNA helicase AAA_7 PF12775.7 OQR89249.1 - 0.36 10.3 2.8 0.8 9.2 0.1 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region ATPase PF06745.13 OQR89249.1 - 0.42 9.9 1.8 2.6 7.3 0.1 2.2 2 0 0 2 2 2 0 KaiC PduV-EutP PF10662.9 OQR89249.1 - 0.51 10.1 3.2 3.5 7.4 0.3 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_28 PF13521.6 OQR89249.1 - 0.8 9.9 2.8 19 5.5 0.7 2.3 2 0 0 2 2 2 0 AAA domain Pkinase_Tyr PF07714.17 OQR89250.1 - 4.8e-11 42.4 0.2 2.4e-10 40.1 0.2 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OQR89250.1 - 7.3e-11 41.9 0.3 1.3e-10 41.1 0.3 1.4 1 1 0 1 1 1 1 Protein kinase domain Peptidase_C69 PF03577.15 OQR89251.1 - 3e-54 184.5 0.0 7.7e-54 183.1 0.0 1.7 1 1 0 1 1 1 1 Peptidase family C69 zf-RING_2 PF13639.6 OQR89251.1 - 3.1e-10 40.2 6.4 6e-10 39.3 6.4 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 OQR89251.1 - 6.8e-07 29.0 7.2 1.3e-06 28.1 7.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 OQR89251.1 - 1.2e-06 28.2 3.1 2.4e-06 27.2 3.1 1.6 1 0 0 1 1 1 1 RING-like zinc finger zf-rbx1 PF12678.7 OQR89251.1 - 1.5e-06 28.4 4.1 3.5e-06 27.2 4.1 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 OQR89251.1 - 9.6e-06 25.5 6.0 1.7e-05 24.7 6.0 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 OQR89251.1 - 3.2e-05 23.7 5.9 5.7e-05 22.9 5.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 OQR89251.1 - 0.00014 21.4 4.8 0.00033 20.2 4.8 1.6 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-RING_UBOX PF13445.6 OQR89251.1 - 0.00018 21.4 1.9 0.00036 20.5 1.9 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 OQR89251.1 - 0.00039 20.2 7.0 0.00069 19.4 7.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 OQR89251.1 - 0.00094 19.0 7.3 0.0017 18.2 7.3 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 OQR89251.1 - 0.0095 16.0 3.3 0.025 14.6 3.3 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger FANCL_C PF11793.8 OQR89251.1 - 0.077 13.2 6.5 0.026 14.7 3.4 1.9 2 0 0 2 2 1 0 FANCL C-terminal domain zf-C3H2C3 PF17122.5 OQR89251.1 - 0.18 11.8 2.9 0.43 10.6 2.9 1.7 1 0 0 1 1 1 0 Zinc-finger zf-RING_4 PF14570.6 OQR89251.1 - 0.86 9.4 10.0 1.8 8.5 10.0 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_10 PF16685.5 OQR89251.1 - 2.5 8.3 5.3 4.9 7.4 5.3 1.4 1 0 0 1 1 1 0 zinc RING finger of MSL2 RINGv PF12906.7 OQR89251.1 - 3 8.1 8.3 6.7 6.9 8.3 1.6 1 0 0 1 1 1 0 RING-variant domain Pkinase_Tyr PF07714.17 OQR89252.1 - 3.3e-07 29.9 0.1 1.9e-06 27.3 0.1 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OQR89252.1 - 8.8e-06 25.3 0.1 1.4e-05 24.6 0.1 1.4 1 1 0 1 1 1 1 Protein kinase domain DUF1242 PF06842.12 OQR89253.1 - 2.1e-15 56.2 1.6 4.5e-15 55.1 1.6 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1242) Pkinase PF00069.25 OQR89253.1 - 1.1e-11 44.6 0.0 1.7e-11 44.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQR89253.1 - 7e-08 32.1 0.0 1.3e-07 31.1 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase TGFb_propeptide PF00688.18 OQR89253.1 - 0.046 13.4 0.8 0.077 12.7 0.8 1.3 1 0 0 1 1 1 0 TGF-beta propeptide SART-1 PF03343.13 OQR89254.1 - 2.6e-27 95.7 11.8 6.7e-22 77.8 7.7 2.2 1 1 1 2 2 2 2 SART-1 family MPM1 PF17234.2 OQR89254.1 - 0.19 12.0 5.1 0.23 11.7 5.1 1.1 1 0 0 1 1 1 0 Mitochondrial peculiar membrane protein 1 Ank_2 PF12796.7 OQR89256.1 - 2.8e-12 47.0 5.5 0.00016 22.2 0.1 3.1 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQR89256.1 - 1.8e-10 41.1 1.9 0.029 15.0 0.1 4.6 3 1 2 5 5 5 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 OQR89256.1 - 3.7e-09 36.7 3.9 0.0015 18.8 0.0 5.4 3 3 3 6 6 6 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQR89256.1 - 4.4e-06 26.6 1.5 21 6.1 0.0 5.8 5 1 1 6 6 6 2 Ankyrin repeat Ank PF00023.30 OQR89256.1 - 0.021 15.2 0.7 39 4.9 0.0 3.9 3 1 1 4 4 4 0 Ankyrin repeat MatE PF01554.18 OQR89262.1 - 8.6e-33 113.3 43.2 5.4e-17 61.9 18.9 2.6 2 0 0 2 2 2 2 MatE MENTAL PF10457.9 OQR89262.1 - 0.015 15.1 5.6 1.5 8.6 0.6 2.6 2 0 0 2 2 2 0 Cholesterol-capturing domain DUF3042 PF11240.8 OQR89262.1 - 0.024 14.6 0.0 1.9 8.5 0.0 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3042) YbgT_YccB PF08173.11 OQR89262.1 - 1.5 9.0 8.9 0.35 11.0 0.4 3.7 3 0 0 3 3 3 0 Membrane bound YbgT-like protein Romo1 PF10247.9 OQR89262.1 - 1.7 9.0 14.0 2.3 8.6 0.6 4.0 2 2 1 3 3 3 0 Reactive mitochondrial oxygen species modulator 1 Polysacc_synt_C PF14667.6 OQR89262.1 - 2.8 8.0 46.9 0.064 13.3 7.4 4.0 5 0 0 5 5 5 0 Polysaccharide biosynthesis C-terminal domain DUF4271 PF14093.6 OQR89262.1 - 3.4 7.5 33.4 0.12 12.2 7.2 3.5 2 2 1 3 3 3 0 Domain of unknown function (DUF4271) ATP19 PF11022.8 OQR89262.1 - 5.5 7.4 0.0 5.5 7.4 0.0 3.7 5 0 0 5 5 5 0 ATP synthase subunit K DUF1281_C PF18406.1 OQR89264.1 - 0.048 13.3 0.2 0.11 12.2 0.2 1.5 1 0 0 1 1 1 0 Ferredoxin-like domain in Api92-like protein tRNA_m1G_MT PF01746.21 OQR89269.1 - 3.2e-21 75.9 0.2 1.2e-20 74.1 0.0 2.0 2 1 0 2 2 2 1 tRNA (Guanine-1)-methyltransferase DUF2122 PF09895.9 OQR89269.1 - 0.11 12.8 0.3 2.2 8.7 0.0 2.4 2 1 0 2 2 2 0 RecB-family nuclease (DUF2122) Orn_Arg_deC_N PF02784.16 OQR89270.1 - 3.2e-38 131.5 0.0 5e-38 130.9 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.22 OQR89270.1 - 1.5e-14 53.9 0.0 3.1e-14 53.0 0.0 1.4 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain CP12 PF02672.15 OQR89271.1 - 0.091 13.5 1.0 0.091 13.5 1.0 2.7 2 1 1 3 3 3 0 CP12 domain LtrA PF06772.11 OQR89272.1 - 2e-19 70.1 13.5 2.4e-19 69.8 13.5 1.0 1 0 0 1 1 1 1 Bacterial low temperature requirement A protein (LtrA) WD40 PF00400.32 OQR89273.1 - 4.4e-14 52.6 28.9 0.00018 22.2 0.1 11.4 13 0 0 13 13 13 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OQR89273.1 - 4.6e-11 42.9 0.4 0.0024 18.1 0.0 7.4 6 1 2 8 8 8 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 OQR89273.1 - 8.3e-05 21.4 0.2 0.0052 15.5 0.0 2.7 2 0 0 2 2 2 1 Nucleoporin Nup120/160 DUF3236 PF11576.8 OQR89273.1 - 0.02 14.6 0.0 0.043 13.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3236) Frtz PF11768.8 OQR89273.1 - 0.032 12.6 0.1 0.13 10.6 0.0 2.0 2 0 0 2 2 2 0 WD repeat-containing and planar cell polarity effector protein Fritz LVIVD PF08309.11 OQR89273.1 - 0.11 11.9 0.0 0.33 10.3 0.0 1.9 1 0 0 1 1 1 0 LVIVD repeat zf-CCCH_4 PF18044.1 OQR89276.1 - 4.4e-09 35.9 16.9 0.00019 21.2 5.5 2.4 2 0 0 2 2 2 2 CCCH-type zinc finger zf-CCCH PF00642.24 OQR89276.1 - 9.2e-08 31.8 13.5 7.2e-05 22.6 1.9 2.6 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) CTD_bind PF04818.13 OQR89276.1 - 4.7e-07 30.5 0.1 1.3e-06 29.1 0.0 1.8 2 0 0 2 2 2 1 RNA polymerase II-binding domain. zf_CCCH_4 PF18345.1 OQR89276.1 - 6.7e-07 29.2 16.1 0.0026 17.7 2.8 2.5 2 0 0 2 2 2 2 Zinc finger domain Torus PF16131.5 OQR89276.1 - 1.5e-05 25.7 2.3 0.001 19.8 0.2 2.7 2 0 0 2 2 2 1 Torus domain zf-CCCH_2 PF14608.6 OQR89276.1 - 0.00064 20.1 13.7 0.0023 18.3 1.6 2.4 2 0 0 2 2 2 2 RNA-binding, Nab2-type zinc finger zf-CCCH_3 PF15663.5 OQR89276.1 - 0.0094 16.2 0.6 2.2 8.6 0.1 2.5 2 0 0 2 2 2 2 Zinc-finger containing family HpaB PF03241.13 OQR89276.1 - 0.13 11.3 0.0 0.23 10.5 0.0 1.3 1 0 0 1 1 1 0 4-hydroxyphenylacetate 3-hydroxylase C terminal Ank_4 PF13637.6 OQR89277.1 - 0.00025 21.5 0.1 0.00041 20.8 0.1 1.3 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 OQR89277.1 - 0.015 15.8 0.1 0.022 15.3 0.1 1.3 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) Ank_2 PF12796.7 OQR89278.1 - 4.7e-17 62.4 16.3 9.9e-07 29.3 0.2 3.3 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQR89278.1 - 1e-15 57.9 1.0 0.00065 20.2 0.0 5.0 2 1 3 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQR89278.1 - 7.7e-11 41.2 0.0 0.73 10.6 0.0 6.2 5 1 1 6 6 6 3 Ankyrin repeat Ank_5 PF13857.6 OQR89278.1 - 3.4e-10 40.0 0.8 0.37 11.2 0.0 6.0 1 1 5 6 6 6 3 Ankyrin repeats (many copies) DUF5049 PF16468.5 OQR89278.1 - 0.00053 19.8 4.7 1.5 8.8 0.0 4.9 3 2 3 6 6 6 1 Domain of unknown function (DUF5049) FAM195 PF14799.6 OQR89278.1 - 0.048 14.0 1.3 3.2 8.2 0.0 3.0 2 2 0 2 2 2 0 FAM195 family ENTH PF01417.20 OQR89278.1 - 0.068 13.2 0.6 7.4 6.6 0.0 2.6 2 2 0 2 2 2 0 ENTH domain Ank PF00023.30 OQR89278.1 - 0.073 13.6 0.3 1.8e+02 2.8 0.1 4.7 3 2 1 4 4 4 0 Ankyrin repeat SapB_1 PF05184.15 OQR89278.1 - 0.42 10.7 7.2 3.5 7.7 0.1 4.3 4 0 0 4 4 4 0 Saposin-like type B, region 1 PhyH PF05721.13 OQR89283.1 - 1.6e-08 35.1 0.2 1.1e-07 32.3 0.2 2.0 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) RelB_transactiv PF16181.5 OQR89284.1 - 0.11 12.7 0.1 0.15 12.3 0.1 1.2 1 0 0 1 1 1 0 RelB transactivation domain cNMP_binding PF00027.29 OQR89287.1 - 7.9e-38 128.4 0.4 4.7e-19 68.2 0.0 2.6 3 0 0 3 3 3 2 Cyclic nucleotide-binding domain DUF5586 PF17824.1 OQR89287.1 - 0.0014 17.8 0.1 0.0018 17.4 0.1 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF5586) ATP-synt_DE_N PF02823.16 OQR89287.1 - 0.0018 18.1 0.1 2.5 8.1 0.0 2.5 2 0 0 2 2 2 2 ATP synthase, Delta/Epsilon chain, beta-sandwich domain MAM33 PF02330.16 OQR89287.1 - 0.0086 16.0 0.8 0.13 12.2 0.0 2.3 2 0 0 2 2 2 1 Mitochondrial glycoprotein DUF5044 PF16447.5 OQR89287.1 - 0.025 14.4 0.1 0.63 9.8 0.0 2.7 2 1 0 3 3 3 0 Domain of unknown function (DUF5044) Dpy-30 PF05186.13 OQR89287.1 - 0.097 12.4 0.2 0.84 9.4 0.2 2.4 2 1 0 2 2 2 0 Dpy-30 motif Ank_2 PF12796.7 OQR89288.1 - 8.8e-25 87.1 3.0 1.9e-14 54.0 0.8 2.5 3 0 0 3 3 3 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OQR89288.1 - 9e-24 81.0 3.1 8.5e-05 22.7 0.2 5.3 5 0 0 5 5 5 4 Ankyrin repeat Ank_4 PF13637.6 OQR89288.1 - 3.1e-22 78.6 10.0 1.2e-08 35.3 0.0 3.8 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 OQR89288.1 - 6.2e-21 74.2 4.7 2.5e-06 27.6 0.2 4.5 3 1 1 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 OQR89288.1 - 5.6e-18 64.5 8.7 1.3e-06 28.6 0.7 4.8 5 0 0 5 5 5 4 Ankyrin repeat Proteasome PF00227.26 OQR89289.1 - 6.3e-27 94.3 0.2 1.5e-26 93.1 0.2 1.6 1 1 0 1 1 1 1 Proteasome subunit WW PF00397.26 OQR89298.1 - 1.1e-07 31.8 1.1 2.3e-07 30.8 1.1 1.6 1 0 0 1 1 1 1 WW domain DUF1218 PF06749.12 OQR89298.1 - 0.31 11.6 7.7 0.82 10.2 7.7 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1218) Copine PF07002.16 OQR89299.1 - 7e-51 172.8 0.0 8.2e-51 172.5 0.0 1.0 1 0 0 1 1 1 1 Copine vWA-TerF-like PF10138.9 OQR89299.1 - 2.1e-11 44.3 0.0 2.3e-11 44.2 0.0 1.1 1 0 0 1 1 1 1 vWA found in TerF C terminus VWA PF00092.28 OQR89299.1 - 0.00051 20.3 0.0 0.0008 19.7 0.0 1.4 1 1 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.6 OQR89299.1 - 0.045 13.7 0.0 0.062 13.2 0.0 1.2 1 0 0 1 1 1 0 von Willebrand factor type A domain AAA_12 PF13087.6 OQR89300.1 - 1.8e-32 112.6 0.0 4.1e-32 111.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 OQR89300.1 - 3.6e-09 36.8 0.6 3.6e-09 36.8 0.6 2.1 2 1 0 2 2 2 1 AAA domain UvrD_C_2 PF13538.6 OQR89300.1 - 0.018 14.9 0.0 0.036 13.9 0.0 1.5 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain AAA_30 PF13604.6 OQR89300.1 - 0.064 13.0 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain COPIIcoated_ERV PF07970.12 OQR89301.1 - 2.9e-70 236.5 1.3 3.3e-70 236.4 0.6 1.5 2 0 0 2 2 2 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 OQR89301.1 - 1.6e-24 86.0 0.1 3.3e-24 85.0 0.1 1.5 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Pkinase PF00069.25 OQR89302.1 - 1e-05 25.1 0.1 1.9e-05 24.2 0.0 1.4 2 0 0 2 2 2 1 Protein kinase domain PI3_PI4_kinase PF00454.27 OQR89308.1 - 2.8e-33 115.8 0.0 3.7e-33 115.4 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase DUF4135 PF13575.6 OQR89308.1 - 0.0032 16.8 0.0 0.004 16.5 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4135) F-box-like PF12937.7 OQR89310.1 - 0.00023 21.0 1.0 0.00044 20.1 1.0 1.4 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 OQR89310.1 - 0.0039 17.0 0.2 0.014 15.3 0.1 2.0 2 0 0 2 2 2 1 F-box domain SMC_hinge PF06470.13 OQR89310.1 - 0.015 15.6 0.0 0.025 14.9 0.0 1.4 1 0 0 1 1 1 0 SMC proteins Flexible Hinge Domain F-box-like PF12937.7 OQR89311.1 - 0.004 17.0 1.5 0.0078 16.1 1.5 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 OQR89311.1 - 0.014 15.2 0.9 0.053 13.4 0.1 2.1 2 0 0 2 2 2 0 F-box domain DUF1598 PF07643.11 OQR89311.1 - 0.17 12.1 0.0 0.31 11.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1598) PI3Ka PF00613.20 OQR89312.1 - 2.6e-46 157.4 0.2 4.8e-46 156.5 0.2 1.4 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3_PI4_kinase PF00454.27 OQR89312.1 - 5.2e-45 154.2 0.1 1.7e-42 146.0 0.1 2.5 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase DUF4135 PF13575.6 OQR89312.1 - 6.5e-05 22.4 0.0 0.00011 21.6 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4135) DUF3136 PF11334.8 OQR89312.1 - 0.0024 17.6 0.0 0.0055 16.5 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3136) HTH_57 PF18679.1 OQR89312.1 - 0.052 13.9 0.1 6.6 7.1 0.0 2.5 2 0 0 2 2 2 0 ThcOx helix turn helix domain E1-E2_ATPase PF00122.20 OQR89319.1 - 2.1e-48 164.3 3.5 3.3e-48 163.6 3.5 1.4 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.26 OQR89319.1 - 5.9e-46 157.4 0.7 1.2e-45 156.4 0.3 1.7 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 OQR89319.1 - 3.6e-06 26.9 1.2 0.0014 18.4 0.9 3.0 2 2 1 3 3 3 2 haloacid dehalogenase-like hydrolase HAD PF12710.7 OQR89319.1 - 5.1e-05 23.8 0.0 0.00016 22.2 0.0 1.9 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 OQR89319.1 - 0.028 14.5 0.3 0.5 10.5 0.0 3.0 3 1 1 4 4 4 0 Haloacid dehalogenase-like hydrolase TPR_12 PF13424.6 OQR89326.1 - 2.9e-17 62.7 6.7 6.7e-11 42.3 1.9 2.5 1 1 1 2 2 2 2 Tetratricopeptide repeat PH PF00169.29 OQR89326.1 - 3.2e-11 43.7 0.1 1.1e-10 41.9 0.1 2.0 1 0 0 1 1 1 1 PH domain TPR_7 PF13176.6 OQR89326.1 - 7.6e-06 25.6 1.3 0.039 14.0 0.1 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat PH_8 PF15409.6 OQR89326.1 - 2.2e-05 24.6 0.4 0.00051 20.3 0.4 3.1 1 1 0 1 1 1 1 Pleckstrin homology domain PH_11 PF15413.6 OQR89326.1 - 5.6e-05 23.5 0.4 0.00032 21.1 0.4 2.3 1 1 0 1 1 1 1 Pleckstrin homology domain TPR_10 PF13374.6 OQR89326.1 - 0.0003 20.6 0.8 2.1 8.3 0.1 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 OQR89326.1 - 0.0084 16.1 0.6 0.5 10.6 0.1 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 OQR89326.1 - 0.019 14.8 0.0 3.2 7.7 0.1 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat EF-hand_6 PF13405.6 OQR89326.1 - 0.044 13.7 0.0 1.5 8.9 0.0 2.8 2 0 0 2 2 2 0 EF-hand domain Pkinase PF00069.25 OQR89333.1 - 3.1e-46 157.9 0.0 5.8e-46 157.0 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQR89333.1 - 1.9e-27 96.2 0.0 2.9e-27 95.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase LRR_4 PF12799.7 OQR89333.1 - 4.4e-13 49.2 16.4 0.0021 18.4 0.1 6.5 3 2 1 6 6 6 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 OQR89333.1 - 3.5e-06 26.8 10.9 25 5.9 0.0 8.7 8 1 0 8 8 8 0 Leucine Rich Repeat Kinase-like PF14531.6 OQR89333.1 - 0.00017 21.0 0.0 0.00034 20.0 0.0 1.4 1 0 0 1 1 1 1 Kinase-like F-box-like PF12937.7 OQR89333.1 - 0.0034 17.3 0.7 0.0093 15.8 0.7 1.7 1 0 0 1 1 1 1 F-box-like LRR_6 PF13516.6 OQR89333.1 - 0.021 14.8 0.3 0.021 14.8 0.3 9.6 11 0 0 11 11 11 0 Leucine Rich repeat Pkinase_fungal PF17667.1 OQR89333.1 - 0.11 11.3 0.0 0.16 10.7 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Acyltransferase PF01553.21 OQR89337.1 - 1.4e-05 24.7 0.0 0.0001 21.9 0.0 2.1 1 1 0 1 1 1 1 Acyltransferase DUF155 PF02582.14 OQR89338.1 - 6.6e-27 94.7 0.9 1.4e-26 93.7 0.9 1.5 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 F420_oxidored PF03807.17 OQR89349.1 - 6.6e-10 39.4 0.0 1.1e-09 38.8 0.0 1.3 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.19 OQR89349.1 - 1.3e-05 24.7 0.0 2.2e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.23 OQR89349.1 - 0.013 15.5 0.5 0.1 12.6 0.5 2.0 1 1 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Rossmann-like PF10727.9 OQR89349.1 - 0.016 15.0 0.1 0.031 14.1 0.1 1.5 1 0 0 1 1 1 0 Rossmann-like domain K_oxygenase PF13434.6 OQR89349.1 - 0.048 12.8 0.1 0.096 11.8 0.1 1.4 1 1 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) Shikimate_DH PF01488.20 OQR89349.1 - 0.12 12.4 0.0 0.2 11.7 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Pyr_redox_2 PF07992.14 OQR89349.1 - 0.13 11.5 0.0 0.18 11.0 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase SSF PF00474.17 OQR89350.1 - 3.3e-06 26.2 26.7 4e-05 22.7 26.7 2.7 1 1 0 1 1 1 1 Sodium:solute symporter family PepSY_TM PF03929.16 OQR89350.1 - 1.6 8.3 9.3 0.39 10.3 2.8 2.5 2 0 0 2 2 2 0 PepSY-associated TM region Tub PF01167.18 OQR89351.1 - 3e-52 177.8 0.0 6.2e-52 176.7 0.0 1.5 1 0 0 1 1 1 1 Tub family zf-RING_2 PF13639.6 OQR89351.1 - 3.6e-08 33.6 11.6 3.6e-08 33.6 11.6 1.8 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 OQR89351.1 - 4.1e-07 29.7 10.8 4.1e-07 29.7 10.8 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 OQR89351.1 - 2e-05 24.4 9.6 2e-05 24.4 9.6 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 OQR89351.1 - 0.00014 21.7 12.2 0.00014 21.7 12.2 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OQR89351.1 - 0.0006 19.8 2.8 0.0006 19.8 2.8 2.1 1 1 1 2 2 2 1 RING-type zinc-finger Prok-RING_4 PF14447.6 OQR89351.1 - 0.00087 19.1 7.6 0.00087 19.1 7.6 2.4 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-rbx1 PF12678.7 OQR89351.1 - 0.0014 18.9 10.1 0.0014 18.9 10.1 2.3 2 1 0 2 2 2 1 RING-H2 zinc finger domain zf-ACC PF17848.1 OQR89351.1 - 0.0055 16.7 0.8 0.0055 16.7 0.8 2.0 2 0 0 2 2 1 1 Acetyl-coA carboxylase zinc finger domain Baculo_IE-1 PF05290.11 OQR89351.1 - 0.0073 16.3 3.2 0.018 15.0 3.2 1.6 1 0 0 1 1 1 1 Baculovirus immediate-early protein (IE-0) zf-MYND PF01753.18 OQR89351.1 - 0.018 15.1 0.3 0.23 11.6 0.3 2.3 1 1 1 2 2 2 0 MYND finger zf-ANAPC11 PF12861.7 OQR89351.1 - 0.058 13.5 3.2 0.12 12.4 3.2 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_6 PF14835.6 OQR89351.1 - 0.23 11.3 4.3 0.63 10.0 4.3 1.7 1 0 0 1 1 1 0 zf-RING of BARD1-type protein FYVE PF01363.21 OQR89351.1 - 0.95 9.6 16.2 5.5 7.2 16.2 2.1 1 1 0 1 1 1 0 FYVE zinc finger zf-RING_10 PF16685.5 OQR89351.1 - 4.2 7.6 11.0 1.1 9.4 7.1 2.0 1 1 0 1 1 1 0 zinc RING finger of MSL2 NmrA PF05368.13 OQR89352.1 - 3.3e-06 26.8 0.0 5.1e-06 26.2 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 OQR89352.1 - 0.0021 18.0 0.3 0.0069 16.3 0.3 1.9 1 1 0 1 1 1 1 NAD(P)H-binding RmlD_sub_bind PF04321.17 OQR89352.1 - 0.011 14.9 0.1 0.04 13.0 0.0 1.8 2 0 0 2 2 2 0 RmlD substrate binding domain RRP36 PF06102.12 OQR89354.1 - 1.3e-44 152.1 35.0 1.6e-44 151.8 35.0 1.1 1 0 0 1 1 1 1 rRNA biogenesis protein RRP36 DUF3723 PF12520.8 OQR89354.1 - 0.0047 15.7 5.2 0.0059 15.3 5.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3723) RmlD_sub_bind PF04321.17 OQR89355.1 - 5.1e-10 38.9 0.0 6.8e-08 32.0 0.0 2.7 1 1 0 1 1 1 1 RmlD substrate binding domain Epimerase PF01370.21 OQR89355.1 - 6e-10 39.0 0.0 4.8e-09 36.0 0.0 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 OQR89355.1 - 1.5e-08 34.8 0.0 2.4e-08 34.1 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 OQR89355.1 - 1.6e-08 33.9 0.0 6.1e-08 32.0 0.0 1.8 1 1 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.13 OQR89355.1 - 7.7e-05 22.4 0.0 0.00012 21.7 0.0 1.4 1 1 0 1 1 1 1 NmrA-like family NAD_binding_4 PF07993.12 OQR89355.1 - 0.0036 16.5 0.1 0.68 9.0 0.0 2.9 2 1 1 3 3 3 1 Male sterility protein Sacchrp_dh_NADP PF03435.18 OQR89355.1 - 0.011 15.9 0.0 0.054 13.8 0.0 2.0 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain Pyr_redox_dim PF02852.22 OQR89356.1 - 3.1e-16 59.6 0.4 3.7e-16 59.3 0.4 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Glyco_hydro_43 PF04616.14 OQR89358.1 - 6.1e-35 120.9 3.9 8.4e-35 120.5 3.9 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 DUF1640 PF07798.11 OQR89358.1 - 1.5e-07 31.6 6.0 2.1e-06 27.9 6.0 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF1640) AI-2E_transport PF01594.16 OQR89359.1 - 8.9e-27 94.1 33.8 4.4e-23 81.9 24.2 3.1 2 1 0 2 2 2 2 AI-2E family transporter DUF4344 PF14247.6 OQR89359.1 - 0.21 11.2 0.0 0.33 10.6 0.0 1.3 1 0 0 1 1 1 0 Putative metallopeptidase Stk19 PF10494.9 OQR89360.1 - 7.1e-21 75.0 1.8 1.4e-20 74.0 1.8 1.4 1 1 0 1 1 1 1 Serine-threonine protein kinase 19 Ctr PF04145.15 OQR89361.1 - 4.8e-18 66.2 0.6 8.2e-18 65.4 0.6 1.3 1 0 0 1 1 1 1 Ctr copper transporter family MORN PF02493.20 OQR89361.1 - 1.7e-10 40.1 29.1 2.2e-05 24.1 0.3 6.0 6 0 0 6 6 6 5 MORN repeat LRR_6 PF13516.6 OQR89362.1 - 1.1e-15 56.2 16.4 0.0059 16.6 0.0 8.2 8 0 0 8 8 8 5 Leucine Rich repeat LRR_1 PF00560.33 OQR89362.1 - 0.00013 22.0 2.0 25 6.0 0.0 6.7 7 1 0 7 7 7 1 Leucine Rich Repeat LRR_8 PF13855.6 OQR89362.1 - 0.00019 21.1 16.5 1.6 8.6 0.1 7.2 5 3 1 6 6 6 3 Leucine rich repeat F-box_4 PF15966.5 OQR89362.1 - 0.0021 17.9 0.2 0.015 15.2 0.1 2.1 2 0 0 2 2 2 1 F-box SwrA PF17423.2 OQR89362.1 - 0.032 14.2 0.2 0.089 12.8 0.1 1.7 2 0 0 2 2 2 0 Swarming motility protein IF-2B PF01008.17 OQR89366.1 - 0.12 11.6 0.0 0.14 11.3 0.0 1.0 1 0 0 1 1 1 0 Initiation factor 2 subunit family Retrotrans_gag PF03732.17 OQR89368.1 - 1.8e-10 41.0 0.0 3.8e-10 39.9 0.0 1.6 1 0 0 1 1 1 1 Retrotransposon gag protein zf-CCHC PF00098.23 OQR89368.1 - 3.3e-07 30.1 3.9 5e-07 29.5 3.9 1.3 1 0 0 1 1 1 1 Zinc knuckle DUF4939 PF16297.5 OQR89368.1 - 8.7e-05 22.4 0.0 0.00018 21.4 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4939) DEC-1_N PF04625.13 OQR89368.1 - 0.0007 18.7 1.1 0.001 18.2 1.1 1.2 1 0 0 1 1 1 1 DEC-1 protein, N-terminal region zf-CCHC_3 PF13917.6 OQR89368.1 - 0.017 15.1 0.9 0.034 14.1 0.9 1.4 1 0 0 1 1 1 0 Zinc knuckle YgbB PF02542.16 OQR89368.1 - 0.04 14.2 0.2 0.11 12.7 0.1 1.7 2 0 0 2 2 2 0 YgbB family SlyX PF04102.12 OQR89368.1 - 0.046 14.3 0.0 0.13 12.9 0.0 1.8 1 0 0 1 1 1 0 SlyX zf-CCHC_4 PF14392.6 OQR89368.1 - 0.11 12.2 0.5 0.19 11.5 0.5 1.4 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_2 PF13696.6 OQR89368.1 - 0.18 11.7 2.4 0.29 11.0 2.4 1.3 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_5 PF14787.6 OQR89368.1 - 5.6 6.8 8.0 0.5 10.1 3.4 1.6 2 0 0 2 2 2 0 GAG-polyprotein viral zinc-finger AA_permease_2 PF13520.6 OQR89371.1 - 5.8e-17 61.6 51.5 6.8e-17 61.4 51.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 OQR89371.1 - 4.4e-12 45.3 45.5 5.7e-12 45.0 45.5 1.0 1 0 0 1 1 1 1 Amino acid permease DUF2807 PF10988.8 OQR89381.1 - 4.4e-22 78.7 15.2 3.7e-13 49.7 9.0 2.1 1 1 1 2 2 2 2 Putative auto-transporter adhesin, head GIN domain F-box-like PF12937.7 OQR89382.1 - 0.045 13.7 0.0 0.13 12.2 0.0 1.9 1 0 0 1 1 1 0 F-box-like zf-HC5HC2H_2 PF13832.6 OQR89384.1 - 1.4e-17 63.8 8.3 1.4e-17 63.8 8.3 3.1 2 1 0 2 2 2 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 OQR89384.1 - 1.3e-12 47.8 6.7 1.3e-12 47.8 6.7 4.4 3 1 1 4 4 4 1 PHD-like zinc-binding domain PHD_2 PF13831.6 OQR89384.1 - 5.7e-12 45.0 2.5 5.7e-12 45.0 2.5 5.4 5 1 0 5 5 5 1 PHD-finger PHD PF00628.29 OQR89384.1 - 2.6e-10 40.0 6.2 2.6e-10 40.0 6.2 5.2 7 1 1 8 8 8 2 PHD-finger Prok-RING_1 PF14446.6 OQR89384.1 - 0.00023 21.0 2.3 0.00023 21.0 2.3 3.3 4 0 0 4 4 4 1 Prokaryotic RING finger family 1 C1_1 PF00130.22 OQR89384.1 - 0.029 14.2 1.6 0.029 14.2 1.6 5.1 6 1 0 6 6 6 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-UDP PF14569.6 OQR89384.1 - 0.96 9.6 7.7 0.12 12.5 2.4 2.3 2 1 1 3 3 3 0 Zinc-binding RING-finger SRCR_2 PF15494.6 OQR89384.1 - 2.2 8.9 6.3 0.17 12.5 0.8 1.9 2 0 0 2 2 2 0 Scavenger receptor cysteine-rich domain zf-Mss51 PF13824.6 OQR89384.1 - 3.2 7.9 8.5 0.35 11.0 1.9 2.6 2 0 0 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 DAP3 PF10236.9 OQR89386.1 - 0.0069 15.6 0.0 0.33 10.1 0.0 2.4 2 0 0 2 2 2 1 Mitochondrial ribosomal death-associated protein 3 DUF3546 PF12066.8 OQR89386.1 - 0.02 15.1 1.6 0.22 11.7 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3546) AAA_25 PF13481.6 OQR89386.1 - 0.11 12.1 0.0 0.38 10.3 0.0 1.9 2 0 0 2 2 2 0 AAA domain PTEN_C2 PF10409.9 OQR89386.1 - 0.13 12.0 1.3 0.25 11.1 0.2 2.0 2 0 0 2 2 2 0 C2 domain of PTEN tumour-suppressor protein Anoctamin PF04547.12 OQR89388.1 - 1.3e-63 215.4 17.1 1.8e-63 214.9 17.1 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel EF-hand_1 PF00036.32 OQR89388.1 - 0.093 12.3 1.0 23 4.8 0.0 3.4 3 0 0 3 3 3 0 EF hand EF-hand_6 PF13405.6 OQR89388.1 - 0.89 9.7 5.2 14 5.9 0.4 3.4 3 0 0 3 3 3 0 EF-hand domain Exo70 PF03081.15 OQR89389.1 - 3.2e-38 131.7 6.6 5.2e-38 131.1 6.6 1.3 1 0 0 1 1 1 1 Exo70 exocyst complex subunit Sec34 PF04136.15 OQR89389.1 - 0.0017 18.3 0.4 0.0057 16.5 0.4 1.9 1 0 0 1 1 1 1 Sec34-like family INTS2 PF14750.6 OQR89390.1 - 6.7e-30 103.5 10.7 7.6e-29 100.0 10.5 2.4 1 1 0 1 1 1 1 Integrator complex subunit 2 CwfJ_C_1 PF04677.15 OQR89391.1 - 3.2e-30 104.5 0.5 5.8e-30 103.7 0.5 1.4 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 CwfJ_C_2 PF04676.14 OQR89391.1 - 3.6e-13 50.2 0.3 9.4e-13 48.9 0.3 1.7 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 2 HIT PF01230.23 OQR89391.1 - 0.019 15.7 1.4 0.078 13.7 1.5 2.1 1 1 0 1 1 1 0 HIT domain zf-LITAF-like PF10601.9 OQR89392.1 - 0.046 14.0 2.0 0.11 12.8 2.0 1.6 1 0 0 1 1 1 0 LITAF-like zinc ribbon domain TMEM72 PF16054.5 OQR89392.1 - 0.061 13.0 2.4 0.097 12.4 2.4 1.2 1 0 0 1 1 1 0 Transmembrane protein family 72 DUF4212 PF13937.6 OQR89392.1 - 1.6 9.2 8.0 5.1 7.6 7.9 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4212) EGF_2 PF07974.13 OQR89395.1 - 4.2e-31 107.0 114.7 5.5e-06 26.6 5.0 10.5 10 0 0 10 10 10 8 EGF-like domain PAP2_C PF14360.6 OQR89395.1 - 3.7e-11 43.4 6.7 3.7e-11 43.4 6.7 2.9 2 0 0 2 2 2 1 PAP2 superfamily C-terminal Laminin_EGF PF00053.24 OQR89395.1 - 0.0015 18.6 2.4 0.0015 18.6 2.4 8.8 8 1 0 8 8 8 7 Laminin EGF domain EGF PF00008.27 OQR89395.1 - 0.0037 17.5 7.1 0.0037 17.5 7.1 11.0 11 0 0 11 11 11 6 EGF-like domain Lipase_GDSL_2 PF13472.6 OQR89396.1 - 1.1e-42 146.4 0.0 4.6e-23 82.5 0.0 2.1 2 0 0 2 2 2 2 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 OQR89396.1 - 1.9e-32 112.9 0.0 6.2e-16 59.0 0.0 2.2 2 0 0 2 2 2 2 GDSL-like Lipase/Acylhydrolase ALGX PF16822.5 OQR89396.1 - 0.0053 16.5 0.0 0.038 13.7 0.0 2.0 2 0 0 2 2 2 1 SGNH hydrolase-like domain, acetyltransferase AlgX Pkinase PF00069.25 OQR89398.1 - 7.9e-50 169.7 0.0 1.3e-49 169.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQR89398.1 - 1.4e-23 83.5 0.0 2.6e-23 82.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase PX PF00787.24 OQR89398.1 - 8.9e-05 22.4 1.9 0.00023 21.1 1.9 1.7 1 0 0 1 1 1 1 PX domain zf-C3HC4_2 PF13923.6 OQR89398.1 - 0.00011 22.0 5.8 0.00011 22.0 5.8 2.7 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 OQR89398.1 - 0.00028 21.1 4.2 0.00028 21.1 4.2 3.1 3 0 0 3 3 2 1 Ring finger domain zf-rbx1 PF12678.7 OQR89398.1 - 0.00054 20.2 9.4 0.0028 17.9 9.4 2.2 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 OQR89398.1 - 0.003 17.5 5.7 0.003 17.5 5.7 2.7 2 1 0 2 2 2 1 zinc-RING finger domain Luteo_PO PF04662.13 OQR89398.1 - 0.0085 15.8 0.3 0.019 14.6 0.3 1.6 1 0 0 1 1 1 1 Luteovirus P0 protein zf-RING_UBOX PF13445.6 OQR89398.1 - 0.014 15.4 2.8 0.1 12.7 2.8 2.5 1 1 0 1 1 1 0 RING-type zinc-finger Kdo PF06293.14 OQR89398.1 - 0.014 14.8 0.4 0.052 12.9 0.4 1.9 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family zf-RING_11 PF17123.5 OQR89398.1 - 0.021 14.6 2.9 0.021 14.6 2.9 2.9 2 1 0 2 2 2 0 RING-like zinc finger Nudix_N_2 PF14803.6 OQR89398.1 - 0.035 14.0 0.7 0.035 14.0 0.7 2.4 3 0 0 3 3 2 0 Nudix N-terminal zf-Nse PF11789.8 OQR89398.1 - 0.089 12.6 1.7 0.23 11.3 1.7 1.6 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4 PF00097.25 OQR89398.1 - 0.093 12.6 13.9 0.084 12.8 10.5 2.7 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 OQR89398.1 - 0.72 10.1 6.5 0.092 12.9 1.9 2.0 2 0 0 2 2 1 0 zinc finger of C3HC4-type, RING zf-ANAPC11 PF12861.7 OQR89398.1 - 2.7 8.1 6.0 0.4 10.7 1.5 1.9 2 0 0 2 2 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING-like PF08746.11 OQR89398.1 - 6.3 7.2 7.7 2.2 8.7 4.3 2.1 2 0 0 2 2 1 0 RING-like domain Zn_ribbon_17 PF17120.5 OQR89398.1 - 7.6 6.2 8.6 5.7 6.6 2.0 2.8 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type cNMP_binding PF00027.29 OQR89400.1 - 5.6e-13 48.8 0.0 1e-12 48.0 0.0 1.5 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Ion_trans PF00520.31 OQR89400.1 - 4.3e-09 36.0 18.7 4.8e-09 35.8 18.1 1.4 1 1 0 1 1 1 1 Ion transport protein Abhydrolase_1 PF00561.20 OQR89404.1 - 6e-21 75.2 0.2 2e-17 63.7 0.6 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 OQR89404.1 - 2.6e-18 67.5 0.0 3.4e-18 67.0 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 OQR89404.1 - 0.002 17.5 0.2 0.0038 16.5 0.2 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 E1-E2_ATPase PF00122.20 OQR89406.1 - 1.6e-31 109.2 5.5 9.6e-20 70.8 0.3 2.7 3 0 0 3 3 3 2 E1-E2 ATPase Cation_ATPase PF13246.6 OQR89406.1 - 3.9e-18 65.3 0.0 7.6e-18 64.4 0.0 1.4 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 OQR89406.1 - 2.7e-16 60.5 0.6 4.5e-15 56.5 0.6 2.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 OQR89406.1 - 4.9e-10 38.9 0.0 1.1e-09 37.8 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 OQR89406.1 - 0.00018 21.4 0.1 0.015 15.1 0.0 2.6 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase Phage_holin_3_6 PF07332.11 OQR89406.1 - 0.0086 16.1 1.9 1.5 8.8 1.0 2.5 2 0 0 2 2 2 2 Putative Actinobacterial Holin-X, holin superfamily III HAD PF12710.7 OQR89406.1 - 0.039 14.3 0.0 0.11 12.8 0.0 1.7 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 OQR89406.1 - 0.13 12.4 0.0 0.3 11.2 0.0 1.6 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase Pkinase PF00069.25 OQR89407.1 - 1.3e-53 182.1 0.4 1e-52 179.1 0.4 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQR89407.1 - 3.8e-27 95.2 0.1 5.4e-27 94.7 0.1 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OQR89407.1 - 1.6e-05 23.9 0.0 0.0001 21.2 0.0 1.9 1 1 1 2 2 2 1 Fungal protein kinase Kdo PF06293.14 OQR89407.1 - 0.00081 18.8 0.1 0.0012 18.2 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family PHD_like PF12910.7 OQR89407.1 - 0.08 13.0 0.0 0.69 9.9 0.0 2.2 2 0 0 2 2 2 0 Antitoxin of toxin-antitoxin, RelE / RelB, TA system Pkinase PF00069.25 OQR89409.1 - 3.5e-19 69.2 0.1 3.9e-19 69.1 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQR89409.1 - 2e-13 50.3 0.3 2.1e-13 50.2 0.3 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 OQR89409.1 - 0.0015 17.9 0.0 0.0026 17.1 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Mannosyl_trans3 PF11051.8 OQR89412.1 - 1.1e-126 421.8 3.7 3.9e-38 131.4 0.1 6.2 5 1 0 5 5 5 5 Mannosyltransferase putative NIF PF03031.18 OQR89412.1 - 0.0016 18.2 1.3 1.2 8.9 0.1 3.6 4 0 0 4 4 4 1 NLI interacting factor-like phosphatase DEP PF00610.21 OQR89412.1 - 0.011 15.8 0.1 2.9 8.0 0.0 3.1 2 0 0 2 2 2 0 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) TMEM164 PF14808.6 OQR89413.1 - 1.2e-20 74.0 12.2 1.6e-20 73.6 12.2 1.1 1 0 0 1 1 1 1 TMEM164 family Ank_5 PF13857.6 OQR89414.1 - 8.3e-12 45.1 2.3 3.6e-05 24.0 0.2 2.6 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 OQR89414.1 - 2.2e-11 44.2 8.0 1.1e-05 26.0 0.2 2.8 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQR89414.1 - 2.4e-08 34.4 4.4 0.00056 20.4 0.2 3.5 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 OQR89414.1 - 3.4e-08 33.6 8.6 0.0016 18.8 0.2 4.9 5 0 0 5 5 5 3 Ankyrin repeat Ank_3 PF13606.6 OQR89414.1 - 3.9e-07 29.8 2.3 0.014 15.9 0.0 5.5 5 0 0 5 5 5 1 Ankyrin repeat Ank_2 PF12796.7 OQR89417.1 - 7.7e-14 52.0 0.7 5.5e-10 39.7 0.1 2.9 1 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OQR89417.1 - 2.1e-11 43.0 4.5 0.00073 19.8 0.1 4.5 5 0 0 5 5 5 3 Ankyrin repeat Ank_4 PF13637.6 OQR89417.1 - 4.6e-09 36.6 0.6 4.3e-07 30.4 0.0 3.5 2 2 2 4 4 4 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 OQR89417.1 - 6.5e-07 29.5 1.8 0.03 14.6 0.1 3.7 3 1 0 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 OQR89417.1 - 0.001 19.4 8.9 0.026 14.9 0.3 4.3 4 1 0 4 4 4 2 Ankyrin repeat Tachystatin_A PF11406.8 OQR89417.1 - 0.1 12.7 0.5 9.5 6.4 0.3 2.4 2 0 0 2 2 2 0 Antimicrobial peptide tachystatin A Ank_2 PF12796.7 OQR89418.1 - 2.2e-12 47.4 0.3 8.6e-12 45.5 0.1 2.0 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQR89418.1 - 4.7e-12 46.2 0.1 9.8e-06 26.0 0.0 3.1 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 OQR89418.1 - 7.4e-11 42.1 0.3 1.1e-05 25.6 0.1 3.3 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQR89418.1 - 1.3e-10 40.5 2.3 0.0059 17.0 0.0 4.5 5 0 0 5 5 5 2 Ankyrin repeat Ank PF00023.30 OQR89418.1 - 2.3e-06 27.8 3.4 0.018 15.5 0.1 3.9 4 0 0 4 4 4 2 Ankyrin repeat DUF2384 PF09722.10 OQR89418.1 - 0.045 13.8 0.1 0.21 11.7 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2384) Ank_2 PF12796.7 OQR89419.1 - 3.3e-20 72.5 0.1 3.9e-11 43.4 0.0 3.1 1 1 3 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQR89419.1 - 2.9e-10 40.5 0.1 5.7e-05 23.6 0.0 3.4 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 OQR89419.1 - 4.3e-10 39.6 0.3 2.2e-05 24.7 0.3 3.3 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQR89419.1 - 1.3e-07 31.3 0.1 0.042 14.4 0.0 4.3 4 0 0 4 4 4 2 Ankyrin repeat Ank PF00023.30 OQR89419.1 - 0.0016 18.8 0.8 3 8.5 0.2 3.5 3 0 0 3 3 3 2 Ankyrin repeat T4_Rnl2_C PF18043.1 OQR89419.1 - 0.032 14.4 0.3 8.6 6.6 0.0 3.0 3 0 0 3 3 3 0 T4 RNA ligase 2 C-terminal SPRY PF00622.28 OQR89420.1 - 9.3e-12 45.1 0.1 1.4e-11 44.5 0.1 1.3 1 0 0 1 1 1 1 SPRY domain F-box-like PF12937.7 OQR89420.1 - 0.00022 21.1 0.4 0.00039 20.3 0.4 1.4 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 OQR89420.1 - 0.0012 18.7 0.1 0.0025 17.6 0.1 1.5 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 OQR89420.1 - 0.038 13.9 0.1 0.069 13.0 0.1 1.4 1 0 0 1 1 1 0 F-box PX PF00787.24 OQR89422.1 - 2.9e-15 56.2 1.2 2.9e-15 56.2 1.2 1.6 2 0 0 2 2 2 1 PX domain DUF4131 PF13567.6 OQR89422.1 - 0.44 10.2 5.7 4.5 6.9 5.7 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4131) SF1-HH PF16275.5 OQR89426.1 - 6.2e-26 91.0 1.9 6.2e-26 91.0 1.9 2.0 2 0 0 2 2 2 1 Splicing factor 1 helix-hairpin domain KH_1 PF00013.29 OQR89426.1 - 1e-08 34.9 0.1 2e-08 34.0 0.1 1.5 1 0 0 1 1 1 1 KH domain PHD_4 PF16866.5 OQR89426.1 - 0.00033 20.7 1.5 0.00078 19.5 1.5 1.7 1 0 0 1 1 1 1 PHD-finger zf-CCHC PF00098.23 OQR89426.1 - 0.037 14.1 2.0 0.037 14.1 2.0 2.4 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_3 PF13917.6 OQR89426.1 - 0.18 11.8 5.8 0.081 12.9 1.6 2.4 1 1 1 2 2 2 0 Zinc knuckle GFO_IDH_MocA PF01408.22 OQR89429.1 - 2.3e-22 80.1 0.5 4.4e-22 79.1 0.1 1.6 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_3 PF03447.16 OQR89429.1 - 4.8e-05 24.0 0.0 6.9e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain GFO_IDH_MocA_C PF02894.17 OQR89429.1 - 0.001 19.0 0.0 0.0018 18.3 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain DUF4160 PF13711.6 OQR89429.1 - 0.057 13.7 2.0 1.2 9.5 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4160) Cellulase PF00150.18 OQR89430.1 - 9.7e-31 107.2 1.4 1.3e-30 106.8 1.4 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) SARAF PF06682.12 OQR89430.1 - 0.0074 16.0 0.0 0.012 15.3 0.0 1.2 1 0 0 1 1 1 1 SOCE-associated regulatory factor of calcium homoeostasis Wzy_C PF04932.15 OQR89430.1 - 0.074 12.7 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 O-Antigen ligase DUF4131 PF13567.6 OQR89430.1 - 0.13 11.9 0.0 0.23 11.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) Wzz PF02706.15 OQR89430.1 - 0.16 12.3 0.4 0.37 11.1 0.4 1.6 1 0 0 1 1 1 0 Chain length determinant protein Cellulase PF00150.18 OQR89431.1 - 3.1e-13 49.8 0.2 4.3e-13 49.3 0.2 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Cellulase-like PF12876.7 OQR89431.1 - 0.066 12.5 0.0 0.089 12.1 0.0 1.2 1 0 0 1 1 1 0 Sugar-binding cellulase-like IQ PF00612.27 OQR89432.1 - 3.1e-11 42.0 32.3 0.0018 17.9 0.7 7.6 7 0 0 7 7 7 6 IQ calmodulin-binding motif DUF3515 PF12028.8 OQR89432.1 - 0.093 12.5 0.0 0.2 11.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3515) Kinesin_assoc PF16183.5 OQR89432.1 - 0.27 11.4 1.4 7.5 6.7 0.1 2.6 2 0 0 2 2 2 0 Kinesin-associated SesA PF17107.5 OQR89432.1 - 2.4 8.3 7.7 0.46 10.7 0.1 2.9 3 0 0 3 3 3 0 N-terminal domain on NACHT_NTPase and P-loop NTPases ABC_membrane PF00664.23 OQR89433.1 - 3.1e-28 99.2 15.0 3.1e-28 99.2 15.0 1.7 1 1 1 2 2 2 2 ABC transporter transmembrane region RasGAP PF00616.19 OQR89433.1 - 0.043 13.5 0.1 0.08 12.6 0.1 1.6 1 0 0 1 1 1 0 GTPase-activator protein for Ras-like GTPase Sensor PF13796.6 OQR89433.1 - 6.3 6.8 12.7 0.081 13.0 2.9 2.3 2 2 0 2 2 2 0 Putative sensor LRR_9 PF14580.6 OQR89434.1 - 4.7e-14 52.3 1.1 8.7e-13 48.1 0.2 2.6 1 1 2 3 3 3 2 Leucine-rich repeat LRR_4 PF12799.7 OQR89434.1 - 3.3e-10 40.1 10.7 1.3e-07 31.8 1.3 3.6 2 1 3 5 5 5 3 Leucine Rich repeats (2 copies) DDE_1 PF03184.19 OQR89434.1 - 4.6e-06 26.4 0.2 2.6e-05 23.9 0.0 2.4 2 1 0 2 2 2 1 DDE superfamily endonuclease LRR_8 PF13855.6 OQR89434.1 - 5.6e-05 22.8 11.0 0.0071 16.1 6.0 3.4 3 0 0 3 3 3 2 Leucine rich repeat LRR_6 PF13516.6 OQR89434.1 - 0.13 12.3 2.0 52 4.3 0.1 3.8 3 0 0 3 3 3 0 Leucine Rich repeat Syntaxin-6_N PF09177.11 OQR89434.1 - 5.8 7.5 7.6 0.87 10.2 2.4 2.4 2 0 0 2 2 2 0 Syntaxin 6, N-terminal Metallophos PF00149.28 OQR89440.1 - 9.1e-23 81.8 0.0 1.5e-22 81.2 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Histidinol_dh PF00815.20 OQR89441.1 - 1.1e-114 383.6 7.1 1.3e-114 383.4 7.1 1.0 1 0 0 1 1 1 1 Histidinol dehydrogenase SNF2_N PF00176.23 OQR89442.1 - 8.2e-73 245.1 0.1 2e-72 243.8 0.1 1.6 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 OQR89442.1 - 4.4e-19 68.8 0.0 2e-18 66.8 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Bromodomain PF00439.25 OQR89442.1 - 9.8e-16 57.6 0.1 2.3e-15 56.4 0.1 1.6 1 0 0 1 1 1 1 Bromodomain ResIII PF04851.15 OQR89442.1 - 2.2e-10 40.8 0.2 1.2e-09 38.4 0.0 2.3 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit SnAC PF14619.6 OQR89442.1 - 1.6e-07 31.8 0.2 4.9e-07 30.2 0.2 1.9 1 0 0 1 1 1 1 Snf2-ATP coupling, chromatin remodelling complex DEAD PF00270.29 OQR89442.1 - 2e-06 27.7 0.0 5.3e-06 26.3 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase SWI2_SNF2 PF18766.1 OQR89442.1 - 9.3e-05 22.2 0.0 0.00029 20.6 0.0 1.8 1 0 0 1 1 1 1 SWI2/SNF2 ATPase HDA2-3 PF11496.8 OQR89442.1 - 0.00027 20.2 0.0 0.0019 17.4 0.0 2.3 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 cNMP_binding PF00027.29 OQR89445.1 - 6.1e-05 23.0 0.0 0.00014 21.9 0.0 1.7 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain T3SS_LEE_assoc PF13327.6 OQR89445.1 - 0.019 15.0 0.2 0.1 12.6 0.1 2.3 2 0 0 2 2 2 0 Type III secretion system subunit Aa_trans PF01490.18 OQR89446.1 - 4.7e-38 130.9 24.9 6.4e-38 130.5 24.9 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Fumarate_red_D PF02313.17 OQR89446.1 - 0.2 11.8 0.1 0.2 11.8 0.1 4.0 4 1 1 5 5 5 0 Fumarate reductase subunit D Rtt106 PF08512.12 OQR89448.1 - 8e-30 103.1 0.0 3.7e-24 85.0 0.0 2.4 2 0 0 2 2 2 2 Histone chaperone Rttp106-like SSrecog PF03531.14 OQR89448.1 - 6.8e-25 86.8 0.0 1.5e-24 85.7 0.0 1.6 1 0 0 1 1 1 1 Structure-specific recognition protein (SSRP1) POB3_N PF17292.2 OQR89448.1 - 2.1e-13 50.5 0.1 3.4e-12 46.6 0.0 2.8 3 1 0 3 3 3 1 POB3-like N-terminal PH domain PH_TFIIH PF08567.11 OQR89448.1 - 0.002 18.4 0.1 0.0079 16.5 0.1 2.0 2 0 0 2 2 2 1 TFIIH p62 subunit, N-terminal domain YL1 PF05764.13 OQR89448.1 - 0.38 10.8 18.9 0.58 10.2 18.9 1.3 1 0 0 1 1 1 0 YL1 nuclear protein Ank_2 PF12796.7 OQR89450.1 - 3.4e-67 223.0 18.1 2.7e-18 66.3 1.7 5.5 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank PF00023.30 OQR89450.1 - 4.2e-58 191.4 30.2 2e-06 28.0 0.1 10.8 10 0 0 10 10 10 10 Ankyrin repeat Ank_4 PF13637.6 OQR89450.1 - 1.5e-51 172.2 10.9 1.4e-10 41.5 0.1 7.5 5 2 2 7 7 7 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQR89450.1 - 1.4e-48 157.2 10.6 3.5e-05 23.8 0.0 10.8 10 0 0 10 10 10 10 Ankyrin repeat Ank_5 PF13857.6 OQR89450.1 - 3.1e-37 126.2 21.6 2.8e-05 24.3 0.0 9.6 2 2 8 10 10 10 10 Ankyrin repeats (many copies) TPR_2 PF07719.17 OQR89450.1 - 3.2e-08 33.1 1.7 0.011 15.8 0.9 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.28 OQR89450.1 - 1.2e-06 28.1 0.9 0.023 14.5 0.4 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.6 OQR89450.1 - 1.5e-05 25.5 1.3 4.6e-05 24.0 1.3 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_12 PF13424.6 OQR89450.1 - 0.00025 21.2 0.4 0.00082 19.6 0.4 1.9 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_8 PF13181.6 OQR89450.1 - 0.0023 18.0 0.7 2.5 8.5 0.5 3.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.6 OQR89450.1 - 0.0033 17.1 2.7 0.0062 16.2 1.5 2.2 1 1 1 2 2 2 1 TPR repeat TPR_17 PF13431.6 OQR89450.1 - 0.011 16.0 2.1 0.076 13.4 0.3 2.9 3 0 0 3 3 2 0 Tetratricopeptide repeat TPR_9 PF13371.6 OQR89450.1 - 0.011 15.8 0.1 0.022 14.9 0.1 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_10 PF13374.6 OQR89450.1 - 0.023 14.5 1.1 0.14 12.1 0.1 2.7 2 1 1 3 3 3 0 Tetratricopeptide repeat FtsZ_C PF12327.8 OQR89450.1 - 0.025 14.9 0.1 0.054 13.8 0.1 1.5 1 0 0 1 1 1 0 FtsZ family, C-terminal domain VWA_3_C PF18571.1 OQR89450.1 - 0.11 12.4 4.3 46 4.0 0.0 4.9 6 0 0 6 6 5 0 von Willebrand factor type A C-terminal domain DUF3856 PF12968.7 OQR89450.1 - 0.11 12.5 0.1 0.35 10.9 0.1 1.8 1 1 0 1 1 1 0 Domain of Unknown Function (DUF3856) TPR_19 PF14559.6 OQR89450.1 - 0.59 10.7 2.9 0.83 10.2 1.5 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat BRCT_2 PF16589.5 OQR89451.1 - 2.6e-13 50.2 0.3 1.7e-07 31.6 0.0 3.1 3 0 0 3 3 3 2 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 OQR89451.1 - 3.6e-12 46.5 0.0 3e-06 27.5 0.0 2.4 2 0 0 2 2 2 2 BRCA1 C Terminus (BRCT) domain Ank PF00023.30 OQR89451.1 - 3.9e-06 27.1 0.0 9.9e-06 25.8 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeat BRCT_3 PF18428.1 OQR89451.1 - 6.5e-06 26.2 0.2 0.00021 21.3 0.2 2.5 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain RTT107_BRCT_5 PF16770.5 OQR89451.1 - 8.7e-06 25.6 0.0 4.2e-05 23.4 0.0 2.1 2 0 0 2 2 2 1 Regulator of Ty1 transposition protein 107 BRCT domain Ank_2 PF12796.7 OQR89451.1 - 0.00012 22.6 0.0 0.00037 21.0 0.0 1.8 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) PTCB-BRCT PF12738.7 OQR89451.1 - 0.00094 19.1 0.0 0.011 15.6 0.0 2.5 2 1 0 2 2 2 1 twin BRCT domain Ank_3 PF13606.6 OQR89451.1 - 0.0099 16.3 0.0 0.036 14.6 0.0 2.0 2 0 0 2 2 2 1 Ankyrin repeat Ank_5 PF13857.6 OQR89451.1 - 0.058 13.7 0.0 0.16 12.3 0.0 1.7 1 0 0 1 1 1 0 Ankyrin repeats (many copies) MFS_1 PF07690.16 OQR89454.1 - 2.5e-30 105.6 35.3 6.4e-28 97.7 26.4 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 OQR89454.1 - 2.2e-07 30.1 22.0 3.1e-06 26.3 4.3 2.1 1 1 1 2 2 2 2 MFS_1 like family Peptidase_S28 PF05577.12 OQR89455.1 - 9.6e-56 189.4 0.1 1.2e-55 189.1 0.1 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase S28 Hydrolase_4 PF12146.8 OQR89455.1 - 1.3e-05 24.6 0.1 2e-05 24.0 0.1 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 OQR89455.1 - 2.3e-05 24.2 0.0 4.4e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S37 PF05576.11 OQR89455.1 - 0.00074 18.3 0.3 0.0028 16.4 0.0 1.8 2 0 0 2 2 2 1 PS-10 peptidase S37 Peptidase_S9 PF00326.21 OQR89455.1 - 0.0013 18.2 0.0 0.0038 16.7 0.0 1.7 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.7 OQR89455.1 - 0.0036 17.9 0.1 0.0055 17.3 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF2920 PF11144.8 OQR89455.1 - 0.18 10.9 0.1 0.31 10.2 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2920) Ank_4 PF13637.6 OQR89456.1 - 1.9e-27 95.3 2.7 1.2e-08 35.3 0.0 3.9 2 1 3 5 5 5 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 OQR89456.1 - 3.8e-25 87.6 0.5 6e-11 42.4 0.0 3.4 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 OQR89456.1 - 7.3e-25 87.4 0.1 3.5e-13 49.9 0.0 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 OQR89456.1 - 7.5e-22 76.8 0.9 3.2e-06 27.3 0.1 4.4 4 0 0 4 4 4 4 Ankyrin repeat Ank_3 PF13606.6 OQR89456.1 - 1.9e-18 64.6 0.0 0.00045 20.5 0.0 4.5 4 0 0 4 4 4 4 Ankyrin repeat MMR_HSR1 PF01926.23 OQR89462.1 - 1.6e-14 53.9 2.6 1e-09 38.5 0.3 2.4 2 0 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.18 OQR89462.1 - 3.6e-07 29.8 0.7 0.003 17.1 0.1 2.3 2 0 0 2 2 2 2 Ferrous iron transport protein B GTP_EFTU PF00009.27 OQR89462.1 - 5.5e-07 29.3 0.3 2.3e-05 24.1 0.0 2.2 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 OQR89462.1 - 8.2e-06 25.8 5.8 0.0082 16.1 0.1 2.9 2 1 1 3 3 3 2 RsgA GTPase Dynamin_N PF00350.23 OQR89462.1 - 5.8e-05 23.2 1.7 0.067 13.2 0.3 2.5 2 0 0 2 2 2 2 Dynamin family AAA_18 PF13238.6 OQR89462.1 - 0.018 15.6 1.1 0.32 11.5 0.1 2.4 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 OQR89462.1 - 0.024 15.0 0.1 0.15 12.4 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain DUF815 PF05673.13 OQR89462.1 - 0.034 13.3 2.7 1.9 7.6 0.0 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF815) Roc PF08477.13 OQR89462.1 - 0.13 12.4 1.4 3.7 7.8 0.1 3.1 2 1 1 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase Peptidase_S10 PF00450.22 OQR89463.1 - 3.4e-63 214.5 0.0 3.9e-63 214.3 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Peptidase_S10 PF00450.22 OQR89464.1 - 1.5e-29 103.7 1.3 1.7e-29 103.5 1.3 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase TUDOR_5 PF18359.1 OQR89473.1 - 4.4e-107 349.7 77.6 2.1e-09 36.9 0.0 14.3 14 0 0 14 14 14 14 Histone methyltransferase Tudor domain 1 Tudor_3 PF18115.1 OQR89473.1 - 2.8e-59 196.8 30.6 0.0001 22.0 0.1 14.1 15 0 0 15 15 15 12 DNA repair protein Crb2 Tudor domain Agenet PF05641.12 OQR89473.1 - 6e-51 170.8 48.4 0.0021 18.5 0.0 14.4 14 0 0 14 14 14 14 Agenet domain DUF4537 PF15057.6 OQR89473.1 - 2.8e-41 140.3 34.0 2.4e-07 30.8 0.2 9.0 5 2 3 9 9 9 8 Domain of unknown function (DUF4537) Tudor_2 PF18104.1 OQR89473.1 - 5.2e-38 128.4 62.6 4.7e-05 23.0 0.1 14.0 14 0 0 14 14 14 11 Jumonji domain-containing protein 2A Tudor domain 53-BP1_Tudor PF09038.10 OQR89473.1 - 2.6e-34 117.8 45.7 0.014 15.3 0.3 13.8 10 3 3 14 14 14 12 Tumour suppressor p53-binding protein-1 Tudor DUF1325 PF07039.11 OQR89473.1 - 1.9e-30 105.6 38.1 0.00027 21.0 0.1 11.8 3 2 9 12 12 12 11 SGF29 tudor-like domain Rad9_Rad53_bind PF08605.10 OQR89473.1 - 2.4e-16 60.1 29.0 0.0073 16.5 0.1 12.8 8 4 5 13 13 13 3 Fungal Rad9-like Rad53-binding LBR_tudor PF09465.10 OQR89473.1 - 1e-11 44.5 56.6 0.21 11.4 0.1 13.5 13 0 0 13 13 13 7 Lamin-B receptor of TUDOR domain PWWP PF00855.17 OQR89473.1 - 1.2e-09 38.5 0.0 16 5.9 0.0 9.0 10 0 0 10 10 10 0 PWWP domain TUDOR PF00567.24 OQR89473.1 - 2.3e-08 34.1 14.3 2 8.4 0.1 8.0 5 2 3 9 9 9 3 Tudor domain DUF5530 PF17670.1 OQR89473.1 - 3.1e-08 33.5 18.4 13 5.6 0.0 11.4 10 3 2 13 13 13 1 Family of unknown function (DUF5530) SH3_15 PF18346.1 OQR89473.1 - 0.6 10.5 18.3 42 4.5 0.2 8.0 8 2 0 8 8 7 0 Mind bomb SH3 repeat domain ILVD_EDD PF00920.21 OQR89473.1 - 0.75 8.3 5.7 2 6.9 0.1 3.5 3 1 1 4 4 4 0 Dehydratase family AAA PF00004.29 OQR89475.1 - 0.017 15.5 0.0 0.039 14.4 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 OQR89475.1 - 0.037 14.6 0.2 0.23 12.0 0.2 2.2 1 1 0 1 1 1 0 AAA domain AAA_17 PF13207.6 OQR89475.1 - 0.042 14.3 0.1 2.3 8.6 0.0 2.4 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 OQR89475.1 - 0.082 12.6 0.0 0.15 11.8 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein SNF5 PF04855.12 OQR89478.1 - 3.8e-14 53.1 0.0 7e-14 52.2 0.0 1.4 1 0 0 1 1 1 1 SNF5 / SMARCB1 / INI1 HTH_31 PF13560.6 OQR89478.1 - 5.9e-05 23.3 0.1 0.00011 22.5 0.1 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_3 PF01381.22 OQR89478.1 - 0.00021 21.3 0.4 0.0012 18.9 0.0 2.1 2 0 0 2 2 2 1 Helix-turn-helix HTH_37 PF13744.6 OQR89478.1 - 0.018 15.0 0.0 0.043 13.8 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_23 PF13384.6 OQR89478.1 - 0.056 13.3 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 Homeodomain-like domain HTH_19 PF12844.7 OQR89478.1 - 0.09 12.8 0.0 0.19 11.7 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain Pox_Ag35 PF03286.14 OQR89479.1 - 0.0097 15.7 1.9 0.011 15.6 1.9 1.1 1 0 0 1 1 1 1 Pox virus Ag35 surface protein GST_C_2 PF13410.6 OQR89479.1 - 0.017 15.2 0.6 0.14 12.2 0.6 2.4 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain EF-1_beta_acid PF10587.9 OQR89479.1 - 0.03 14.8 6.3 0.03 14.8 6.3 2.6 2 0 0 2 2 2 0 Eukaryotic elongation factor 1 beta central acidic region GST_C PF00043.25 OQR89479.1 - 0.11 12.7 2.4 0.25 11.6 0.3 2.4 2 1 0 2 2 2 0 Glutathione S-transferase, C-terminal domain PBP1_TM PF14812.6 OQR89479.1 - 0.35 11.3 6.4 0.46 10.9 6.4 1.2 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Ribosomal_60s PF00428.19 OQR89479.1 - 3.3 8.4 20.7 0.61 10.7 15.4 2.1 1 1 1 2 2 2 0 60s Acidic ribosomal protein DDHD PF02862.17 OQR89483.1 - 0.00026 21.2 2.7 0.00074 19.8 1.8 1.9 2 0 0 2 2 2 1 DDHD domain DUF676 PF05057.14 OQR89483.1 - 0.02 14.4 0.1 0.24 10.9 0.0 2.1 2 0 0 2 2 2 0 Putative serine esterase (DUF676) WWE PF02825.20 OQR89483.1 - 0.032 14.8 0.0 0.087 13.4 0.0 1.7 2 0 0 2 2 2 0 WWE domain GBP PF02263.19 OQR89484.1 - 6.9e-73 245.1 0.1 3.5e-72 242.8 0.0 2.2 2 0 0 2 2 2 1 Guanylate-binding protein, N-terminal domain GBP_C PF02841.14 OQR89484.1 - 3.4e-14 52.9 12.2 3.4e-14 52.9 12.2 3.1 1 1 1 3 3 3 1 Guanylate-binding protein, C-terminal domain MMR_HSR1 PF01926.23 OQR89484.1 - 0.0013 18.7 0.1 0.0046 17.0 0.1 2.0 1 0 0 1 1 1 1 50S ribosome-binding GTPase NPV_P10 PF05531.12 OQR89484.1 - 0.26 11.8 5.2 5.3 7.6 1.6 3.2 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein UPF0565 PF10561.9 OQR89485.1 - 2.6e-44 151.7 0.0 1.9e-21 76.6 0.1 2.1 1 1 1 2 2 2 2 Uncharacterised protein family UPF0565 Ras PF00071.22 OQR89488.1 - 2e-43 147.8 0.0 2.4e-43 147.5 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OQR89488.1 - 1e-29 103.2 0.0 1.5e-29 102.6 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OQR89488.1 - 1.3e-14 54.1 0.0 1.6e-14 53.7 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family DLIC PF05783.11 OQR89488.1 - 3.3e-07 29.5 0.0 0.0014 17.6 0.0 2.1 2 0 0 2 2 2 2 Dynein light intermediate chain (DLIC) Gtr1_RagA PF04670.12 OQR89488.1 - 3e-05 23.5 0.0 3.9e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 OQR89488.1 - 0.00094 19.3 0.1 0.0023 18.0 0.0 1.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_7 PF12775.7 OQR89488.1 - 0.0094 15.5 0.0 0.033 13.7 0.0 1.9 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_16 PF13191.6 OQR89488.1 - 0.024 15.0 0.0 0.035 14.5 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain TniB PF05621.11 OQR89488.1 - 0.025 14.0 0.0 0.047 13.1 0.0 1.4 1 0 0 1 1 1 0 Bacterial TniB protein SRPRB PF09439.10 OQR89488.1 - 0.049 13.1 0.0 0.069 12.6 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit NitrOD2 PF18550.1 OQR89488.1 - 0.16 12.1 0.1 3.4 7.8 0.0 2.4 1 1 2 3 3 3 0 Nitrososphaera output domain 2 Sigma54_activat PF00158.26 OQR89488.1 - 0.19 11.4 0.0 0.34 10.6 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain ABC2_membrane_3 PF12698.7 OQR89489.1 - 9.8e-20 70.9 26.1 9.8e-20 70.9 26.1 1.6 2 0 0 2 2 2 1 ABC-2 family transporter protein ABC_tran PF00005.27 OQR89489.1 - 2.1e-13 51.0 0.0 3.8e-13 50.1 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_23 PF13476.6 OQR89489.1 - 0.0027 18.2 0.3 0.0027 18.2 0.3 1.6 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 OQR89489.1 - 0.0033 17.1 0.3 0.0074 16.0 0.3 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 OQR89489.1 - 0.0053 16.7 0.0 0.0095 15.9 0.0 1.3 1 0 0 1 1 1 1 RsgA GTPase AAA_15 PF13175.6 OQR89489.1 - 0.054 13.2 0.1 0.094 12.4 0.1 1.3 1 0 0 1 1 1 0 AAA ATPase domain AAA_21 PF13304.6 OQR89489.1 - 0.067 13.0 0.1 0.14 11.9 0.1 1.5 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system Lebercilin PF15619.6 OQR89490.1 - 0.014 15.1 10.9 0.24 11.1 5.5 2.2 1 1 1 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease DUF5094 PF17015.5 OQR89490.1 - 0.019 15.1 2.9 0.032 14.3 2.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5094) PRT_C PF08372.10 OQR89490.1 - 0.027 14.2 0.5 0.037 13.8 0.5 1.3 1 0 0 1 1 1 0 Plant phosphoribosyltransferase C-terminal DUF5499 PF17603.2 OQR89490.1 - 0.059 14.0 0.2 0.097 13.3 0.2 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5499) Herpes_BLRF2 PF05812.12 OQR89490.1 - 0.16 12.1 4.3 0.8 9.9 0.8 2.5 2 1 1 3 3 3 0 Herpesvirus BLRF2 protein YabA PF06156.13 OQR89490.1 - 0.45 11.2 8.2 0.67 10.6 6.3 2.0 1 1 1 2 2 2 0 Initiation control protein YabA MatE PF01554.18 OQR89491.1 - 4.3e-34 117.5 33.4 6.4e-21 74.7 12.8 2.3 2 0 0 2 2 2 2 MatE Ank_5 PF13857.6 OQR89494.1 - 0.0053 17.1 0.0 0.0089 16.3 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeats (many copies) ATP-synt_ab_C PF00306.27 OQR89495.1 - 4e-08 33.7 0.1 5.3e-08 33.2 0.1 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain PIG-P PF08510.12 OQR89495.1 - 0.025 14.5 1.1 0.025 14.5 1.1 1.9 2 0 0 2 2 2 0 PIG-P 2TM PF13239.6 OQR89495.1 - 0.049 13.9 2.8 0.073 13.4 2.8 1.3 1 0 0 1 1 1 0 2TM domain Na_H_antiport_3 PF07399.11 OQR89497.1 - 0.034 13.0 0.1 0.043 12.7 0.1 1.1 1 0 0 1 1 1 0 Putative Na+/H+ antiporter Glyoxalase PF00903.25 OQR89502.1 - 5.5e-09 36.3 0.1 6.6e-09 36.0 0.1 1.1 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 OQR89502.1 - 0.00049 20.9 0.0 0.00058 20.6 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase-like domain MIP PF00230.20 OQR89503.1 - 4.4e-51 173.8 4.5 6.1e-51 173.3 4.5 1.2 1 0 0 1 1 1 1 Major intrinsic protein DDE_3 PF13358.6 OQR89505.1 - 9.8e-06 25.4 0.2 0.00029 20.6 0.1 2.7 2 1 0 2 2 2 1 DDE superfamily endonuclease Tenui_NCP PF04876.12 OQR89505.1 - 0.061 12.9 0.3 0.35 10.4 0.1 2.1 1 1 1 2 2 2 0 Tenuivirus major non-capsid protein E1-E2_ATPase PF00122.20 OQR89507.1 - 4.2e-24 85.1 3.2 2.1e-20 73.0 0.1 3.2 3 0 0 3 3 3 3 E1-E2 ATPase Cation_ATPase_N PF00690.26 OQR89507.1 - 7e-13 48.1 0.0 1.1e-12 47.4 0.0 1.4 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus E1-E2_ATPase PF00122.20 OQR89508.1 - 2.1e-36 125.2 7.0 9.2e-25 87.2 0.8 3.0 3 0 0 3 3 3 2 E1-E2 ATPase Cation_ATPase_N PF00690.26 OQR89508.1 - 1.4e-14 53.5 0.0 2.7e-14 52.6 0.0 1.5 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Sulfate_transp PF00916.20 OQR89508.1 - 0.01 14.6 3.5 0.063 12.0 0.1 2.2 2 0 0 2 2 2 0 Sulfate permease family Hydrolase PF00702.26 OQR89508.1 - 0.026 14.8 0.1 0.063 13.6 0.1 1.7 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase DUF3792 PF12670.7 OQR89508.1 - 0.49 10.6 0.1 0.49 10.6 0.1 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF3792) zf-C2H2 PF00096.26 OQR89511.1 - 1.3e-11 44.3 25.3 0.00024 21.4 1.6 3.5 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 OQR89511.1 - 1.1e-08 35.2 21.8 0.0014 19.3 3.1 3.4 3 0 0 3 3 3 3 C2H2-type zinc finger zf-H2C2_2 PF13465.6 OQR89511.1 - 9.8e-08 32.1 19.7 0.00018 21.8 3.4 4.2 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_11 PF16622.5 OQR89511.1 - 0.0002 21.0 1.2 0.0002 21.0 1.2 3.1 3 0 0 3 3 3 1 zinc-finger C2H2-type zf-C2H2_8 PF15909.5 OQR89511.1 - 0.087 13.1 9.0 0.38 11.1 8.5 2.0 1 1 0 1 1 1 0 C2H2-type zinc ribbon zf-C2H2_aberr PF17017.5 OQR89511.1 - 0.1 12.8 0.0 0.1 12.8 0.0 2.6 2 1 0 2 2 2 0 Aberrant zinc-finger zf-TRAF PF02176.18 OQR89511.1 - 0.35 11.6 10.3 0.12 13.1 3.1 2.3 2 0 0 2 2 2 0 TRAF-type zinc finger FOXP-CC PF16159.5 OQR89511.1 - 0.45 11.2 8.8 2.4 8.8 0.1 3.3 1 1 2 3 3 3 0 FOXP coiled-coil domain zf-C2H2_jaz PF12171.8 OQR89511.1 - 0.9 9.9 14.1 0.77 10.1 0.9 3.2 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 OQR89511.1 - 1 9.8 11.1 2.9 8.4 0.1 3.4 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-C2HE PF16278.5 OQR89511.1 - 2.1 8.9 11.5 10 6.7 0.4 2.7 2 0 0 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger Zn-C2H2_12 PF18112.1 OQR89511.1 - 9.3 6.8 8.0 23 5.6 0.9 3.0 3 0 0 3 3 3 0 Autophagy receptor zinc finger-C2H2 domain HECT PF00632.25 OQR89513.1 - 8.2e-84 281.7 0.0 1.3e-83 281.0 0.0 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) zf-RanBP PF00641.18 OQR89513.1 - 0.1 12.0 1.6 0.24 10.8 0.2 2.2 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others PP2C PF00481.21 OQR89515.1 - 4.5e-57 193.6 0.1 7.7e-57 192.9 0.0 1.4 2 0 0 2 2 2 1 Protein phosphatase 2C PP2C_2 PF13672.6 OQR89515.1 - 2.4e-07 30.6 0.0 4.7e-07 29.7 0.0 1.5 1 1 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 OQR89515.1 - 0.015 15.2 0.0 3.5 7.5 0.0 2.2 2 0 0 2 2 2 0 Stage II sporulation protein E (SpoIIE) Thioredoxin_15 PF18403.1 OQR89515.1 - 0.022 14.7 0.1 0.054 13.4 0.0 1.7 2 0 0 2 2 2 0 Thioredoxin-like domain PseudoU_synth_1 PF01416.20 OQR89516.1 - 2.9e-10 40.6 0.4 2.8e-09 37.4 0.0 2.4 3 0 0 3 3 3 1 tRNA pseudouridine synthase DUF1296 PF06972.11 OQR89516.1 - 0.049 13.8 0.4 0.23 11.6 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1296) HutD PF05962.11 OQR89517.1 - 3.3e-34 118.5 0.0 3.7e-34 118.3 0.0 1.0 1 0 0 1 1 1 1 HutD RCC1 PF00415.18 OQR89518.1 - 2.3e-77 255.5 5.0 1.1e-13 51.5 0.1 7.9 7 1 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 OQR89518.1 - 2.2e-36 122.9 22.5 1.7e-10 40.4 0.0 8.1 8 0 0 8 8 8 6 Regulator of chromosome condensation (RCC1) repeat PHD PF00628.29 OQR89518.1 - 8.7e-05 22.3 18.6 8.7e-05 22.3 18.6 2.5 2 1 0 2 2 2 1 PHD-finger Glyoxalase PF00903.25 OQR89522.1 - 2.8e-12 46.9 0.0 3.1e-12 46.8 0.0 1.0 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 OQR89522.1 - 0.0045 17.3 0.0 0.012 15.8 0.0 1.7 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Ank_2 PF12796.7 OQR89523.1 - 4.3e-29 100.9 0.3 4.7e-13 49.5 0.0 3.8 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQR89523.1 - 4.6e-27 94.0 0.3 4.4e-09 36.7 0.0 5.0 2 1 4 6 6 6 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 OQR89523.1 - 3.1e-25 87.9 0.3 4.6e-12 45.9 0.1 4.2 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQR89523.1 - 6.3e-21 72.2 0.1 0.00011 22.3 0.0 5.6 5 0 0 5 5 5 4 Ankyrin repeat Ank PF00023.30 OQR89523.1 - 9.2e-19 67.0 0.1 9.9e-05 22.6 0.0 4.9 4 0 0 4 4 4 4 Ankyrin repeat HTH_Tnp_Tc5 PF03221.16 OQR89523.1 - 0.00012 22.0 0.3 0.0045 17.0 0.0 2.4 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain PAD PF03068.15 OQR89523.1 - 0.038 13.0 0.1 0.06 12.3 0.1 1.2 1 0 0 1 1 1 0 Protein-arginine deiminase (PAD) LRR_4 PF12799.7 OQR89524.1 - 3.4e-07 30.5 5.4 1.9 9.0 0.6 5.6 4 1 1 5 5 5 3 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 OQR89524.1 - 0.013 15.5 2.2 0.098 12.6 0.5 2.4 2 0 0 2 2 2 0 BspA type Leucine rich repeat region (6 copies) Sigma54_DBD PF04552.13 OQR89524.1 - 0.04 13.6 0.2 4.9 6.8 0.0 2.3 2 0 0 2 2 2 0 Sigma-54, DNA binding domain LRR_6 PF13516.6 OQR89524.1 - 0.27 11.4 4.0 27 5.2 0.0 5.1 6 0 0 6 6 6 0 Leucine Rich repeat Peptidase_C3 PF00548.20 OQR89530.1 - 0.11 12.4 0.0 0.22 11.4 0.0 1.4 1 0 0 1 1 1 0 3C cysteine protease (picornain 3C) Aa_trans PF01490.18 OQR89533.1 - 1.6e-40 139.1 18.6 2.1e-40 138.7 18.6 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Hum_adeno_E3A PF05393.11 OQR89533.1 - 3.3 7.8 7.5 0.47 10.5 0.6 2.8 2 1 1 3 3 3 0 Human adenovirus early E3A glycoprotein RRF PF01765.19 OQR89535.1 - 9.7e-44 149.2 2.2 9.7e-44 149.2 2.2 1.6 2 0 0 2 2 2 1 Ribosome recycling factor Ank_2 PF12796.7 OQR89535.1 - 2.7e-18 66.3 6.4 2.9e-10 40.6 0.5 3.6 1 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQR89535.1 - 3.6e-14 52.9 2.5 0.0033 18.0 0.1 5.5 3 3 2 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQR89535.1 - 6.6e-11 41.5 0.3 0.87 10.4 0.0 6.5 6 0 0 6 6 6 3 Ankyrin repeat Ank_5 PF13857.6 OQR89535.1 - 1e-08 35.3 1.2 1.5 9.2 0.1 5.9 3 2 2 5 5 5 3 Ankyrin repeats (many copies) Ank PF00023.30 OQR89535.1 - 0.0056 17.1 4.2 6.4 7.4 0.0 5.5 3 2 1 4 4 4 1 Ankyrin repeat REF PF05755.12 OQR89535.1 - 0.18 11.6 1.5 0.18 11.6 0.2 1.6 2 0 0 2 2 2 0 Rubber elongation factor protein (REF) DUF5049 PF16468.5 OQR89535.1 - 0.92 9.4 3.9 26 4.8 0.0 4.3 5 1 1 6 6 6 0 Domain of unknown function (DUF5049) YtxH PF12732.7 OQR89535.1 - 1.6 9.4 7.8 0.29 11.7 3.4 2.0 2 0 0 2 2 2 0 YtxH-like protein MMS19_N PF14500.6 OQR89536.1 - 1.4e-65 221.5 2.7 1.4e-65 221.5 2.7 2.3 2 0 0 2 2 2 1 Dos2-interacting transcription regulator of RNA-Pol-II MMS19_C PF12460.8 OQR89536.1 - 1.5e-38 133.0 1.0 1.5e-38 133.0 1.0 3.0 2 1 0 3 3 3 1 RNAPII transcription regulator C-terminal DUF3385 PF11865.8 OQR89536.1 - 0.021 14.7 1.7 8.2 6.3 0.1 4.0 3 0 0 3 3 3 0 Domain of unknown function (DUF3385) Arm PF00514.23 OQR89536.1 - 1.2 9.2 7.9 35 4.6 0.0 5.8 6 1 1 7 7 7 0 Armadillo/beta-catenin-like repeat Ank_2 PF12796.7 OQR89538.1 - 5e-49 164.8 28.0 3.2e-11 43.7 4.7 8.0 3 3 4 8 8 8 8 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQR89538.1 - 7.1e-38 128.5 28.9 2.3e-06 28.0 0.0 10.2 6 3 3 9 9 9 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQR89538.1 - 7.4e-33 108.9 29.4 0.0019 18.5 0.0 16.2 17 0 0 17 17 15 8 Ankyrin repeat Ank_5 PF13857.6 OQR89538.1 - 1.7e-29 101.4 24.7 3.9e-06 27.0 0.0 11.1 5 3 8 14 14 14 11 Ankyrin repeats (many copies) DUF4537 PF15057.6 OQR89538.1 - 2.4e-15 56.6 5.9 0.043 13.9 0.1 8.7 8 0 0 8 8 8 4 Domain of unknown function (DUF4537) Ank PF00023.30 OQR89538.1 - 6.4e-14 51.7 35.0 2.4e-05 24.6 0.0 11.7 13 0 0 13 13 13 4 Ankyrin repeat RCC1 PF00415.18 OQR89538.1 - 2.6e-10 40.8 5.7 0.0024 18.5 0.0 5.1 4 0 0 4 4 4 2 Regulator of chromosome condensation (RCC1) repeat DUF1325 PF07039.11 OQR89538.1 - 1.9e-09 37.7 2.5 0.25 11.4 0.1 5.8 6 0 0 6 6 6 3 SGF29 tudor-like domain RCC1_2 PF13540.6 OQR89538.1 - 4.3e-06 26.4 23.2 0.059 13.2 0.0 7.3 8 0 0 8 8 8 2 Regulator of chromosome condensation (RCC1) repeat LBR_tudor PF09465.10 OQR89538.1 - 0.0077 16.0 0.2 20 5.1 0.0 4.4 4 0 0 4 4 4 0 Lamin-B receptor of TUDOR domain Tudor_2 PF18104.1 OQR89538.1 - 0.02 14.5 9.8 0.52 10.0 0.0 6.0 7 0 0 7 7 7 0 Jumonji domain-containing protein 2A Tudor domain LicD PF04991.13 OQR89542.1 - 1.5e-21 77.6 0.0 1.2e-20 74.6 0.0 2.0 1 1 0 1 1 1 1 LicD family ELFV_dehydrog PF00208.21 OQR89545.1 - 1.2e-33 116.8 0.0 2.2e-33 116.0 0.0 1.3 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Bac_GDH PF05088.12 OQR89545.1 - 1.2e-20 72.8 0.5 2.4e-18 65.2 0.4 2.5 2 1 0 2 2 2 2 Bacterial NAD-glutamate dehydrogenase SHIPPO-rpt PF07004.12 OQR89545.1 - 7.3e-12 45.6 29.2 0.62 11.1 0.1 10.3 10 0 0 10 10 10 6 Sperm-tail PG-rich repeat ELFV_dehydrog_N PF02812.18 OQR89545.1 - 0.00072 19.4 0.0 0.0022 17.9 0.0 1.8 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain Pkinase PF00069.25 OQR89546.1 - 0.0055 16.1 0.2 0.0056 16.1 0.2 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase PF00069.25 OQR89547.1 - 1e-50 172.6 0.1 1.3e-50 172.2 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQR89547.1 - 7.9e-31 107.3 0.0 1e-30 106.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 OQR89547.1 - 0.0011 18.9 0.1 0.092 12.6 0.2 2.2 1 1 0 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 OQR89547.1 - 0.0096 15.3 0.0 0.018 14.4 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 OQR89547.1 - 0.025 14.0 0.0 0.041 13.2 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PCAF_N PF06466.11 OQR89547.1 - 0.041 13.5 0.0 0.067 12.7 0.0 1.3 1 0 0 1 1 1 0 PCAF (P300/CBP-associated factor) N-terminal domain RIO1 PF01163.22 OQR89547.1 - 0.076 12.6 0.1 0.13 11.8 0.1 1.3 1 0 0 1 1 1 0 RIO1 family Acyl_transf_3 PF01757.22 OQR89549.1 - 8.7e-10 38.2 3.5 1.1e-09 37.8 3.5 1.2 1 0 0 1 1 1 1 Acyltransferase family Folate_carrier PF01770.18 OQR89552.1 - 1.1e-63 215.4 24.0 2.4e-63 214.3 24.0 1.5 1 1 0 1 1 1 1 Reduced folate carrier MFS_1 PF07690.16 OQR89552.1 - 6.7e-09 35.1 24.4 0.00018 20.6 1.5 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 OQR89552.1 - 0.035 12.9 20.5 0.039 12.8 0.8 3.1 2 1 1 3 3 3 0 MFS_1 like family AAA_11 PF13086.6 OQR89553.1 - 6.5e-61 206.4 1.1 1.8e-60 204.9 1.1 1.8 1 0 0 1 1 1 1 AAA domain AAA_12 PF13087.6 OQR89553.1 - 1.1e-53 181.8 0.0 2.5e-53 180.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain SEN1_N PF12726.7 OQR89553.1 - 2.8e-12 45.7 6.5 2.8e-12 45.7 6.5 2.7 4 1 0 4 4 4 1 SEN1 N terminal AAA_30 PF13604.6 OQR89553.1 - 2.1e-09 37.4 0.4 0.00045 20.0 0.1 2.6 2 0 0 2 2 2 2 AAA domain Med26 PF08711.11 OQR89553.1 - 4.2e-09 36.3 0.5 1.2e-08 34.8 0.5 1.9 1 0 0 1 1 1 1 TFIIS helical bundle-like domain AAA_19 PF13245.6 OQR89553.1 - 3.6e-07 30.6 1.6 0.011 16.1 0.0 3.5 3 1 0 3 3 3 2 AAA domain Viral_helicase1 PF01443.18 OQR89553.1 - 0.00084 19.2 0.1 2 8.1 0.0 3.7 3 1 1 4 4 4 2 Viral (Superfamily 1) RNA helicase APG6_N PF17675.1 OQR89553.1 - 0.26 11.8 2.6 1.1 9.8 2.6 2.1 1 0 0 1 1 1 0 Apg6 coiled-coil region hnRNP_Q_AcD PF18360.1 OQR89554.1 - 8.3e-25 86.5 0.0 6.3e-10 38.9 0.0 3.3 3 0 0 3 3 3 3 Heterogeneous nuclear ribonucleoprotein Q acidic domain DUF1640 PF07798.11 OQR89555.1 - 2.9e-07 30.7 8.0 8.8e-06 25.9 8.0 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF1640) DHHA2 PF02833.14 OQR89555.1 - 0.0002 21.6 0.3 0.00065 19.9 0.1 1.8 2 0 0 2 2 2 1 DHHA2 domain DDE_Tnp_IS240 PF13610.6 OQR89555.1 - 0.015 15.5 1.6 0.025 14.8 1.4 1.5 1 1 0 1 1 1 0 DDE domain HALZ PF02183.18 OQR89555.1 - 0.017 15.4 0.8 4.2 7.7 0.1 2.9 2 0 0 2 2 2 0 Homeobox associated leucine zipper CbiK PF06180.11 OQR89555.1 - 0.035 13.4 0.6 0.14 11.5 0.3 1.8 1 1 1 2 2 2 0 Cobalt chelatase (CbiK) Polysacc_deac_2 PF04748.13 OQR89555.1 - 0.062 12.5 1.9 0.27 10.4 0.2 2.0 1 1 1 2 2 2 0 Divergent polysaccharide deacetylase CCDC24 PF15669.5 OQR89555.1 - 0.21 11.4 4.0 0.2 11.5 2.2 1.7 1 1 1 2 2 2 0 Coiled-coil domain-containing protein 24 family Enkurin PF13864.6 OQR89555.1 - 0.24 11.8 8.2 1.8 9.0 3.2 2.3 1 1 1 2 2 2 0 Calmodulin-binding Torus PF16131.5 OQR89559.1 - 1.1e-32 113.0 0.8 3.7e-32 111.3 0.8 2.0 1 0 0 1 1 1 1 Torus domain WW PF00397.26 OQR89559.1 - 1.2e-09 38.1 3.0 1.2e-09 38.1 3.0 2.0 2 0 0 2 2 2 1 WW domain RRM_1 PF00076.22 OQR89559.1 - 3.1e-07 30.1 0.0 8.8e-07 28.7 0.0 1.9 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-RanBP PF00641.18 OQR89559.1 - 0.00069 18.9 4.4 0.0017 17.7 4.4 1.6 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others zf_CCCH_4 PF18345.1 OQR89559.1 - 0.022 14.8 5.4 0.074 13.1 5.4 2.0 1 0 0 1 1 1 0 Zinc finger domain RE_AspBHI_N PF18062.1 OQR89559.1 - 0.058 12.9 0.1 0.14 11.7 0.1 1.6 1 0 0 1 1 1 0 Restriction endonuclease AspBHI N-terminal zf-CCCH PF00642.24 OQR89559.1 - 4.7 7.2 10.8 4.3 7.4 6.5 2.4 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-Sec23_Sec24 PF04810.15 OQR89559.1 - 7.5 6.7 6.8 15 5.7 0.1 2.9 2 0 0 2 2 2 0 Sec23/Sec24 zinc finger Pkinase PF00069.25 OQR89561.1 - 2.2e-44 151.8 0.0 3.1e-44 151.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQR89561.1 - 2.3e-24 86.1 0.0 3e-24 85.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Methyltransf_16 PF10294.9 OQR89561.1 - 2.7e-24 85.8 0.0 1.2e-23 83.7 0.0 1.9 2 0 0 2 2 2 1 Lysine methyltransferase PrmA PF06325.13 OQR89561.1 - 3.9e-05 23.2 0.0 6e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) APH PF01636.23 OQR89561.1 - 9e-05 22.5 0.0 0.00017 21.6 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Methyltransf_23 PF13489.6 OQR89561.1 - 0.00069 19.5 0.0 0.0015 18.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 OQR89561.1 - 0.0014 18.2 0.0 0.005 16.4 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase small domain DDE_Tnp_IS66_C PF13817.6 OQR89561.1 - 1.4 9.2 2.9 1.1 9.6 0.2 2.2 3 0 0 3 3 3 0 IS66 C-terminal element DUF2434 PF10361.9 OQR89562.1 - 0.033 13.2 0.2 0.053 12.5 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2434) Spore_coat_CotO PF14153.6 OQR89563.1 - 0.062 13.2 10.9 0.11 12.4 10.9 1.4 1 0 0 1 1 1 0 Spore coat protein CotO SpoIIIAH PF12685.7 OQR89563.1 - 0.1 12.4 8.7 0.18 11.6 8.7 1.4 1 0 0 1 1 1 0 SpoIIIAH-like protein Raftlin PF15250.6 OQR89563.1 - 0.27 9.9 12.2 3.6 6.2 0.0 2.1 2 0 0 2 2 2 0 Raftlin SAPS PF04499.15 OQR89563.1 - 0.28 9.9 11.4 0.37 9.5 11.4 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Zip PF02535.22 OQR89563.1 - 1.3 8.2 10.1 2 7.6 10.1 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Vfa1 PF08432.10 OQR89563.1 - 1.5 9.2 22.4 0.076 13.3 14.6 2.2 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 Hid1 PF12722.7 OQR89563.1 - 1.9 6.5 6.3 2.8 6.0 6.3 1.3 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Nop14 PF04147.12 OQR89563.1 - 5.7 5.0 30.0 0.46 8.6 25.3 1.5 2 0 0 2 2 2 0 Nop14-like family CLASP_N PF12348.8 OQR89564.1 - 2.7e-27 95.8 2.1 3e-17 62.9 0.7 3.7 3 0 0 3 3 3 3 CLASP N terminal HEAT_2 PF13646.6 OQR89564.1 - 3.9e-10 40.0 5.5 0.0029 17.9 0.0 6.8 6 1 1 7 7 7 2 HEAT repeats HEAT_EZ PF13513.6 OQR89564.1 - 2.2e-07 31.2 19.1 0.0055 17.2 0.1 9.4 12 0 0 12 12 12 2 HEAT-like repeat HEAT PF02985.22 OQR89564.1 - 4e-06 26.6 19.9 0.62 10.5 0.1 9.6 11 0 0 11 11 11 3 HEAT repeat Vac14_Fab1_bd PF12755.7 OQR89564.1 - 2.7e-05 24.7 0.3 1.2 9.8 0.0 5.0 4 0 0 4 4 4 1 Vacuolar 14 Fab1-binding region Cnd1 PF12717.7 OQR89564.1 - 0.00014 21.9 15.4 0.012 15.6 0.1 6.6 6 2 0 6 6 6 2 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 OQR89564.1 - 0.00053 18.7 12.4 0.15 10.6 1.3 4.7 4 2 1 5 5 5 4 Adaptin N terminal region RTP1_C1 PF10363.9 OQR89564.1 - 0.00085 19.5 1.7 2.1 8.5 0.0 5.2 5 0 0 5 5 5 1 Required for nuclear transport of RNA pol II C-terminus 1 IFRD PF05004.13 OQR89564.1 - 0.0016 17.6 0.6 0.44 9.6 0.0 2.6 2 0 0 2 2 2 2 Interferon-related developmental regulator (IFRD) Thioredoxin_8 PF13905.6 OQR89567.1 - 1.5e-23 83.0 0.0 1.9e-23 82.6 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin PF00085.20 OQR89567.1 - 8.9e-10 38.5 0.0 1.9e-07 31.0 0.0 2.1 1 1 1 2 2 2 2 Thioredoxin Redoxin PF08534.10 OQR89567.1 - 6.1e-06 26.0 0.0 7.6e-06 25.7 0.0 1.1 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 OQR89567.1 - 6.3e-06 26.1 0.0 8.2e-06 25.8 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_2 PF13098.6 OQR89567.1 - 0.0002 21.8 0.0 0.00029 21.2 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_9 PF14595.6 OQR89567.1 - 0.00029 20.6 0.0 0.5 10.1 0.0 2.1 1 1 1 2 2 2 2 Thioredoxin Thioredoxin_7 PF13899.6 OQR89567.1 - 0.031 14.5 0.0 0.063 13.5 0.0 1.7 1 1 0 1 1 1 0 Thioredoxin-like Anoctamin PF04547.12 OQR89568.1 - 4.7e-119 398.2 14.8 6.1e-119 397.8 14.8 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel Anoct_dimer PF16178.5 OQR89568.1 - 0.037 13.7 0.5 0.16 11.7 0.1 2.1 2 0 0 2 2 2 0 Dimerisation domain of Ca+-activated chloride-channel, anoctamin RSN1_7TM PF02714.15 OQR89568.1 - 0.11 11.8 11.4 0.021 14.1 7.3 1.9 2 0 0 2 2 2 0 Calcium-dependent channel, 7TM region, putative phosphate dCMP_cyt_deam_1 PF00383.23 OQR89571.1 - 4.2e-28 97.2 0.2 1.3e-27 95.7 0.0 1.9 2 0 0 2 2 2 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 OQR89571.1 - 5.2e-16 58.6 0.9 1.8e-15 56.9 0.0 2.1 2 1 0 2 2 2 1 MafB19-like deaminase Gln-synt_C-ter PF18318.1 OQR89571.1 - 0.019 14.8 0.0 0.053 13.4 0.0 1.7 1 0 0 1 1 1 0 Glutamine synthetase C-terminal domain APOBEC4_like PF18774.1 OQR89571.1 - 0.025 14.5 0.1 0.061 13.3 0.1 1.7 1 0 0 1 1 1 0 APOBEC4-like -AID/APOBEC-deaminase APOBEC3 PF18771.1 OQR89571.1 - 0.037 14.2 0.1 0.12 12.5 0.1 1.9 1 0 0 1 1 1 0 APOBEC3 SNAD4 PF18750.1 OQR89571.1 - 0.082 13.0 1.0 0.12 12.5 0.1 1.8 2 0 0 2 2 2 0 Secreted Novel AID/APOBEC-like Deaminase 4 CTU2 PF10288.9 OQR89571.1 - 0.092 13.0 0.9 0.17 12.1 0.9 1.5 1 0 0 1 1 1 0 Cytoplasmic tRNA 2-thiolation protein 2 SMC_N PF02463.19 OQR89572.1 - 0.00064 19.2 0.2 0.00079 18.9 0.2 1.1 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain Pro_sub2 PF18513.1 OQR89579.1 - 0.13 12.5 0.0 0.24 11.6 0.0 1.5 1 0 0 1 1 1 0 Prodomain subtilisin 2 EMP24_GP25L PF01105.24 OQR89580.1 - 2.7e-10 40.5 0.0 4.1e-10 39.9 0.0 1.2 1 1 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Ank_4 PF13637.6 OQR89582.1 - 1.8e-05 25.2 3.4 0.038 14.6 0.0 4.4 5 0 0 5 5 5 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 OQR89582.1 - 2.6e-05 24.7 0.7 0.037 14.6 0.1 2.7 3 0 0 3 3 3 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OQR89582.1 - 0.017 15.6 1.5 13 6.8 0.0 4.5 5 0 0 5 5 5 0 Ankyrin repeat Ank_5 PF13857.6 OQR89583.1 - 5.6e-05 23.3 0.1 0.0088 16.3 0.0 2.1 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 OQR89583.1 - 0.001 19.6 0.0 0.0012 19.4 0.0 1.2 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQR89583.1 - 0.016 15.8 0.0 0.087 13.4 0.0 1.9 1 1 0 1 1 1 0 Ankyrin repeats (many copies) Ank PF00023.30 OQR89583.1 - 0.04 14.4 0.0 11 6.6 0.0 2.3 1 1 1 2 2 2 0 Ankyrin repeat Ank_3 PF13606.6 OQR89583.1 - 0.082 13.5 0.0 8.1 7.4 0.0 2.3 2 1 0 2 2 2 0 Ankyrin repeat Ank_2 PF12796.7 OQR89584.1 - 3.1e-11 43.7 0.3 4e-07 30.5 0.1 2.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OQR89584.1 - 7.8e-08 32.4 0.2 0.59 10.5 0.0 4.2 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 OQR89584.1 - 6e-06 26.7 0.2 0.019 15.6 0.0 3.5 2 1 1 3 3 3 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQR89584.1 - 5.1e-05 23.4 0.1 5.7 7.8 0.0 4.2 3 1 1 4 4 4 2 Ankyrin repeat Ank PF00023.30 OQR89584.1 - 0.00014 22.1 0.8 4.5 7.9 0.6 4.3 1 1 1 2 2 2 1 Ankyrin repeat DUF5049 PF16468.5 OQR89584.1 - 0.11 12.4 0.0 7.9 6.5 0.0 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF5049) DER1 PF04511.15 OQR89585.1 - 3.7e-51 173.8 12.9 4.2e-51 173.6 12.9 1.0 1 0 0 1 1 1 1 Der1-like family DUF4286 PF14114.6 OQR89587.1 - 1.9e-13 50.7 0.0 3e-13 50.1 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4286) Glyco_hydro_18 PF00704.28 OQR89588.1 - 8.4e-09 35.6 0.1 1.3e-08 35.0 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 TACI-CRD2 PF09305.10 OQR89588.1 - 0.014 15.4 0.3 0.029 14.4 0.3 1.5 1 0 0 1 1 1 0 TACI, cysteine-rich domain Glyco_hydro_18 PF00704.28 OQR89589.1 - 2.3e-17 63.7 2.0 5.1e-17 62.6 2.0 1.5 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 FYVE PF01363.21 OQR89590.1 - 4.7e-09 36.3 15.2 9.9e-09 35.2 15.2 1.4 1 0 0 1 1 1 1 FYVE zinc finger START PF01852.19 OQR89590.1 - 7.7e-08 32.0 0.0 1.7e-07 30.8 0.0 1.6 1 0 0 1 1 1 1 START domain DUF3074 PF11274.8 OQR89590.1 - 0.0025 17.8 0.0 0.0042 17.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3074) DUF3692 PF12469.8 OQR89590.1 - 0.06 13.6 0.0 0.27 11.5 0.0 1.9 2 0 0 2 2 2 0 CRISPR-associated protein FYVE_2 PF02318.16 OQR89590.1 - 0.084 13.1 5.6 0.21 11.8 5.6 1.6 1 0 0 1 1 1 0 FYVE-type zinc finger zf-C3HC4 PF00097.25 OQR89590.1 - 0.11 12.4 12.6 0.3 11.0 11.7 2.3 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-CRD PF17979.1 OQR89590.1 - 1.8 8.7 14.1 6.3 6.9 14.1 1.9 1 1 0 1 1 1 0 Cysteine rich domain with multizinc binding regions PTA_PTB PF01515.19 OQR89594.1 - 6.7e-114 380.5 2.0 1e-113 379.9 2.0 1.3 1 0 0 1 1 1 1 Phosphate acetyl/butaryl transferase AAA_26 PF13500.6 OQR89594.1 - 5.8e-20 72.0 0.0 1.3e-19 70.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain DRTGG PF07085.12 OQR89594.1 - 1.3e-15 57.1 1.3 2.5e-15 56.1 0.1 2.2 3 0 0 3 3 3 1 DRTGG domain Ykof PF07615.11 OQR89594.1 - 0.16 12.5 0.3 2.4 8.7 0.0 2.7 2 0 0 2 2 2 0 YKOF-related Family Ank_2 PF12796.7 OQR89595.1 - 7.9e-37 125.7 2.7 1.3e-13 51.4 0.1 4.5 2 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OQR89595.1 - 6.7e-30 102.8 2.0 3e-12 46.5 0.0 5.2 3 2 2 5 5 5 5 Ankyrin repeats (many copies) Ank_4 PF13637.6 OQR89595.1 - 1.1e-25 89.6 0.3 4.7e-07 30.2 0.1 5.7 4 1 1 5 5 5 5 Ankyrin repeats (many copies) Ank PF00023.30 OQR89595.1 - 1.6e-25 88.3 5.9 0.00096 19.5 0.0 8.0 8 0 0 8 8 8 6 Ankyrin repeat Ank_3 PF13606.6 OQR89595.1 - 1e-21 74.6 0.4 0.00022 21.4 0.0 7.6 8 0 0 8 8 8 5 Ankyrin repeat Pkinase PF00069.25 OQR89595.1 - 9.7e-10 38.2 0.0 6.4e-09 35.5 0.0 2.2 1 1 1 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQR89595.1 - 1.4e-09 37.6 0.0 5.2e-09 35.8 0.0 1.9 1 1 1 2 2 2 1 Protein tyrosine kinase Shigella_OspC PF06128.11 OQR89595.1 - 0.036 13.8 0.1 2.3 7.9 0.0 2.3 2 0 0 2 2 2 0 Shigella flexneri OspC protein Abhydrolase_3 PF07859.13 OQR89601.1 - 1.2e-40 139.7 0.0 1.7e-40 139.2 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 OQR89601.1 - 5.9e-21 74.8 0.1 3.6e-19 68.9 0.1 2.0 2 0 0 2 2 2 2 Steryl acetyl hydrolase Hydrolase_4 PF12146.8 OQR89601.1 - 0.0024 17.2 0.1 0.083 12.1 0.0 2.2 1 1 1 2 2 2 1 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 OQR89601.1 - 0.062 12.8 0.3 0.57 9.6 0.3 2.1 1 1 0 1 1 1 0 Prolyl oligopeptidase family WD40 PF00400.32 OQR89602.1 - 4.4e-39 131.8 17.1 1e-07 32.5 0.2 7.7 8 0 0 8 8 8 7 WD domain, G-beta repeat EF-hand_1 PF00036.32 OQR89602.1 - 5.3e-25 85.1 9.3 4.9e-09 35.1 0.0 4.7 4 0 0 4 4 4 3 EF hand EF-hand_7 PF13499.6 OQR89602.1 - 5.6e-23 81.2 5.5 4.7e-14 52.6 0.3 2.5 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 OQR89602.1 - 1.5e-21 74.4 5.1 2.4e-09 36.4 0.0 4.2 4 0 0 4 4 4 3 EF-hand domain EF-hand_5 PF13202.6 OQR89602.1 - 2.1e-15 55.4 9.9 7.1e-06 25.3 0.0 4.2 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.6 OQR89602.1 - 1.2e-14 53.9 12.6 5.4e-08 32.6 0.4 4.8 2 2 2 4 4 4 3 EF-hand domain pair ANAPC4_WD40 PF12894.7 OQR89602.1 - 9.3e-12 45.1 0.8 0.00065 19.9 0.2 5.2 2 1 3 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain EF-hand_9 PF14658.6 OQR89602.1 - 1.2e-05 25.5 0.1 0.12 12.8 0.0 2.4 2 0 0 2 2 2 2 EF-hand domain Nup160 PF11715.8 OQR89602.1 - 0.00015 20.6 7.0 0.34 9.5 0.1 4.4 1 1 2 4 4 4 2 Nucleoporin Nup120/160 PALB2_WD40 PF16756.5 OQR89602.1 - 0.0012 17.8 0.1 0.0052 15.8 0.0 2.1 2 0 0 2 2 2 1 Partner and localizer of BRCA2 WD40 domain WD40_3 PF15911.5 OQR89602.1 - 0.0026 17.7 0.0 0.13 12.3 0.0 2.6 2 0 0 2 2 2 1 WD domain, G-beta repeat EF-hand_14 PF17959.1 OQR89602.1 - 0.0058 16.9 0.6 0.27 11.6 0.1 2.3 2 0 0 2 2 2 1 EF-hand domain eIF2A PF08662.11 OQR89602.1 - 0.014 15.3 0.1 7.3 6.4 0.1 2.9 2 1 0 3 3 3 0 Eukaryotic translation initiation factor eIF2A Nucleoporin_N PF08801.11 OQR89602.1 - 0.022 13.5 0.1 2.8 6.6 0.0 3.3 1 1 1 3 3 3 0 Nup133 N terminal like EF-hand_4 PF12763.7 OQR89602.1 - 0.06 13.3 6.9 1.2 9.2 0.6 4.5 3 1 1 4 4 4 0 Cytoskeletal-regulatory complex EF hand Acetyltransf_11 PF13720.6 OQR89602.1 - 0.076 13.5 0.3 3.7 8.1 0.0 3.0 3 0 0 3 3 3 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 Hira PF07569.11 OQR89602.1 - 0.094 12.4 1.2 1.3 8.7 0.1 3.2 2 1 1 3 3 3 0 TUP1-like enhancer of split DUF3008 PF11450.8 OQR89602.1 - 0.12 12.6 0.3 0.38 10.9 0.3 1.8 1 0 0 1 1 1 0 Protein of unknwon function (DUF3008) Ank PF00023.30 OQR89603.1 - 1.6e-20 72.5 0.7 2.2e-05 24.7 0.0 6.2 6 0 0 6 6 6 4 Ankyrin repeat Ank_2 PF12796.7 OQR89603.1 - 2.5e-20 72.9 2.1 2.2e-07 31.3 0.9 3.2 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OQR89603.1 - 3.5e-20 71.8 0.3 7.5e-07 29.3 0.0 4.3 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 OQR89603.1 - 1e-13 51.4 1.6 0.027 15.1 0.0 5.5 3 2 3 6 6 6 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQR89603.1 - 2.5e-11 42.7 2.5 0.0067 16.8 0.0 7.0 6 2 0 6 6 6 3 Ankyrin repeat Glyco_trans_1_2 PF13524.6 OQR89604.1 - 3.4e-06 27.4 0.0 7.1e-06 26.3 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 DUF2062 PF09835.9 OQR89605.1 - 0.033 14.1 0.0 0.049 13.5 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2062) Mid2 PF04478.12 OQR89605.1 - 0.066 13.0 0.0 0.1 12.4 0.0 1.3 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor Myb_DNA-bind_5 PF13873.6 OQR89607.1 - 0.29 11.2 9.0 0.12 12.5 1.2 3.2 2 1 0 3 3 3 0 Myb/SANT-like DNA-binding domain Lyase_1 PF00206.20 OQR89609.1 - 4.7e-109 364.6 0.2 6.2e-109 364.2 0.2 1.2 1 0 0 1 1 1 1 Lyase FumaraseC_C PF10415.9 OQR89609.1 - 3.2e-26 91.5 2.0 6.7e-26 90.5 0.3 2.5 3 0 0 3 3 3 1 Fumarase C C-terminus tRNA-synt_1 PF00133.22 OQR89611.1 - 1.5e-216 720.3 0.0 2.2e-216 719.8 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 OQR89611.1 - 8.9e-25 87.4 0.1 1.9e-24 86.4 0.1 1.5 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 OQR89611.1 - 2.9e-14 52.7 0.6 0.00026 19.8 0.4 4.0 3 1 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1e PF01406.19 OQR89611.1 - 2.3e-05 23.9 0.0 0.00024 20.5 0.0 2.6 2 0 0 2 2 2 1 tRNA synthetases class I (C) catalytic domain BRCT_2 PF16589.5 OQR89614.1 - 0.0064 16.9 0.0 0.19 12.1 0.0 2.2 2 0 0 2 2 2 2 BRCT domain, a BRCA1 C-terminus domain BRCT_2 PF16589.5 OQR89615.1 - 0.00044 20.6 0.0 0.39 11.2 0.0 2.1 2 0 0 2 2 2 2 BRCT domain, a BRCA1 C-terminus domain PTCB-BRCT PF12738.7 OQR89615.1 - 0.016 15.1 0.0 0.026 14.5 0.0 1.3 1 0 0 1 1 1 0 twin BRCT domain BRCT PF00533.26 OQR89615.1 - 0.028 14.8 0.0 0.88 10.0 0.0 2.1 2 0 0 2 2 2 0 BRCA1 C Terminus (BRCT) domain cNMP_binding PF00027.29 OQR89617.1 - 1.4e-19 69.9 0.0 2.4e-19 69.2 0.0 1.4 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Ion_trans PF00520.31 OQR89617.1 - 8.5e-14 51.4 6.8 1.3e-13 50.8 6.8 1.2 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 OQR89617.1 - 0.015 15.3 0.4 0.015 15.3 0.4 2.0 2 0 0 2 2 2 0 Ion channel LRR_4 PF12799.7 OQR89619.1 - 1.3e-13 50.8 16.6 7.6e-07 29.4 2.6 3.7 2 1 1 3 3 3 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 OQR89619.1 - 6.3e-10 38.7 14.4 4e-05 23.3 2.2 3.7 1 1 3 4 4 4 4 Leucine rich repeat LRR_6 PF13516.6 OQR89619.1 - 3.7e-06 26.6 13.9 1.3 9.3 0.1 6.0 5 1 1 6 6 6 4 Leucine Rich repeat LRR_9 PF14580.6 OQR89619.1 - 9.6e-06 25.2 1.9 1.7e-05 24.4 1.9 1.4 1 0 0 1 1 1 1 Leucine-rich repeat LRR_1 PF00560.33 OQR89619.1 - 0.00043 20.5 14.8 19 6.3 0.1 6.3 4 1 1 5 5 5 2 Leucine Rich Repeat Asp5 PF17000.5 OQR89619.1 - 0.043 13.9 0.0 0.093 12.9 0.0 1.6 1 0 0 1 1 1 0 Accessory secretory protein Sec, Asp5 CCDC53 PF10152.9 OQR89620.1 - 6.6e-53 179.2 8.0 1.5e-37 129.4 0.0 3.2 3 1 0 3 3 3 2 Subunit CCDC53 of WASH complex PARP_reg PF02877.14 OQR89621.1 - 8.6e-44 148.9 1.8 1.5e-43 148.2 1.8 1.4 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase, regulatory domain WGR PF05406.15 OQR89621.1 - 4.8e-14 52.2 0.2 1.3e-13 50.8 0.2 1.8 1 0 0 1 1 1 1 WGR domain Baculo_PP31 PF05311.11 OQR89621.1 - 0.0099 15.4 0.5 0.036 13.5 0.6 1.7 1 1 0 1 1 1 1 Baculovirus 33KDa late protein (PP31) PARP PF00644.20 OQR89621.1 - 0.044 13.4 0.1 0.18 11.4 0.1 2.1 2 0 0 2 2 2 0 Poly(ADP-ribose) polymerase catalytic domain Ank_2 PF12796.7 OQR89624.1 - 1.2e-15 57.8 2.6 0.00017 22.1 0.0 3.6 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQR89624.1 - 1.3e-11 44.7 0.3 0.01 16.4 0.0 4.9 3 2 1 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQR89624.1 - 7.4e-09 35.2 0.0 2.1 9.2 0.0 4.9 5 0 0 5 5 5 3 Ankyrin repeat Ank_5 PF13857.6 OQR89624.1 - 8.4e-05 22.8 0.0 0.38 11.1 0.0 4.3 4 1 1 5 5 5 1 Ankyrin repeats (many copies) DUF5049 PF16468.5 OQR89624.1 - 0.00044 20.1 1.0 1.1 9.2 0.0 3.8 3 2 1 4 4 4 2 Domain of unknown function (DUF5049) Ank PF00023.30 OQR89624.1 - 0.047 14.1 0.0 1.3e+02 3.3 0.0 4.1 4 0 0 4 4 4 0 Ankyrin repeat Pox_A3L PF05288.11 OQR89624.1 - 0.12 12.4 0.0 0.9 9.6 0.0 2.4 2 0 0 2 2 2 0 Poxvirus A3L Protein Ank_4 PF13637.6 OQR89625.1 - 9.8e-11 42.0 0.0 8.2e-05 23.1 0.0 2.1 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 OQR89625.1 - 7.2e-09 35.7 0.1 0.013 15.8 0.2 2.9 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 OQR89625.1 - 1.8e-07 31.7 0.0 2.9e-07 31.0 0.0 1.3 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OQR89625.1 - 8.9e-06 25.7 0.0 0.48 11.1 0.0 2.8 3 0 0 3 3 3 2 Ankyrin repeat Ank_2 PF12796.7 OQR89627.1 - 5.6e-10 39.7 1.0 0.00012 22.6 0.0 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQR89627.1 - 7.9e-08 32.7 2.2 0.00081 19.9 0.0 2.4 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 OQR89627.1 - 7.4e-06 26.1 0.4 0.19 12.1 0.0 3.0 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQR89627.1 - 2.6e-05 24.3 0.5 0.68 10.7 0.0 3.1 3 0 0 3 3 3 2 Ankyrin repeat Ank_2 PF12796.7 OQR89628.1 - 1.1e-27 96.4 16.7 1.2e-07 32.2 0.1 5.3 2 1 4 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQR89628.1 - 3.1e-25 88.2 6.6 2.8e-06 27.8 0.0 6.8 7 0 0 7 7 7 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 OQR89628.1 - 1.4e-13 50.8 15.5 0.081 13.3 0.0 9.1 4 3 6 10 10 10 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQR89628.1 - 4.4e-12 45.1 8.3 0.076 13.6 0.0 9.4 12 0 0 12 12 12 3 Ankyrin repeat Ank PF00023.30 OQR89628.1 - 2.2e-06 27.9 3.9 16 6.1 0.0 7.6 7 1 0 7 7 7 1 Ankyrin repeat Ank_2 PF12796.7 OQR89629.1 - 5.4e-14 52.5 2.1 1.3e-07 32.1 0.1 3.3 1 1 3 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQR89629.1 - 4.2e-12 46.3 4.5 3e-06 27.7 0.1 3.8 3 1 0 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQR89629.1 - 8.2e-05 22.7 7.7 2.7 8.8 0.0 6.0 7 0 0 7 7 7 2 Ankyrin repeat Ank_5 PF13857.6 OQR89629.1 - 0.054 13.8 5.7 0.51 10.7 0.0 4.0 4 1 2 6 6 6 0 Ankyrin repeats (many copies) Helicase_PWI PF18149.1 OQR89629.1 - 0.063 13.5 0.1 3.1 8.0 0.1 2.4 1 1 1 2 2 2 0 N-terminal helicase PWI domain Baculo_19 PF04798.12 OQR89629.1 - 0.17 11.6 1.8 1.6 8.5 0.1 2.8 3 0 0 3 3 3 0 Baculovirus 19 kDa protein conserved region Ank_2 PF12796.7 OQR89630.1 - 3.7e-15 56.3 10.9 2.2e-06 28.1 0.8 3.0 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQR89630.1 - 1.1e-12 48.2 0.5 0.00019 22.0 0.0 3.2 3 0 0 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 OQR89630.1 - 3e-10 40.2 2.4 0.00052 20.2 0.1 4.0 2 2 2 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQR89630.1 - 1.6e-09 37.2 0.6 0.59 10.9 0.0 4.9 4 1 1 5 5 5 3 Ankyrin repeat DUF5049 PF16468.5 OQR89630.1 - 1.7e-06 27.8 2.0 1.7 8.6 0.0 4.9 1 1 4 5 5 5 3 Domain of unknown function (DUF5049) Syntaxin PF00804.25 OQR89631.1 - 6.9e-34 117.3 11.4 1.1e-33 116.6 11.4 1.3 1 0 0 1 1 1 1 Syntaxin SNARE PF05739.19 OQR89631.1 - 1.4e-13 50.6 0.8 3.7e-13 49.2 0.8 1.8 1 0 0 1 1 1 1 SNARE domain DLP_helical PF18709.1 OQR89631.1 - 0.078 12.2 10.4 0.4 9.8 2.0 2.9 2 1 1 3 3 3 0 Dynamin-like helical domain Syntaxin_2 PF14523.6 OQR89631.1 - 0.12 12.7 8.9 0.049 14.0 1.9 2.6 2 1 0 2 2 2 0 Syntaxin-like protein PAH PF02671.21 OQR89631.1 - 1.9 8.7 4.3 6.1 7.1 4.3 2.0 1 1 0 1 1 1 0 Paired amphipathic helix repeat Pkinase_Tyr PF07714.17 OQR89636.1 - 0.00012 21.5 0.1 0.00059 19.2 0.0 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase LRR_8 PF13855.6 OQR89636.1 - 0.0011 18.7 13.0 0.097 12.5 5.7 3.3 1 1 2 3 3 3 3 Leucine rich repeat Pkinase PF00069.25 OQR89636.1 - 0.005 16.2 0.2 0.1 12.0 0.1 2.3 2 0 0 2 2 2 1 Protein kinase domain LRR_4 PF12799.7 OQR89636.1 - 0.016 15.6 24.0 0.1 13.1 4.9 3.7 3 1 1 4 4 4 0 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 OQR89636.1 - 0.096 12.8 4.8 6.2 7.1 0.1 4.3 4 0 0 4 4 4 0 Leucine Rich repeat EphA2_TM PF14575.6 OQR89636.1 - 0.17 12.8 0.0 0.39 11.6 0.0 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain LRR_1 PF00560.33 OQR89636.1 - 6.3 7.8 12.2 4.9 8.1 0.5 4.8 3 1 1 4 4 4 0 Leucine Rich Repeat HHH_3 PF12836.7 OQR89637.1 - 5.6e-08 32.9 0.0 1.9e-07 31.2 0.0 1.9 1 0 0 1 1 1 1 Helix-hairpin-helix motif HHH_6 PF14579.6 OQR89637.1 - 2.5e-05 24.4 0.0 0.00014 22.0 0.0 2.3 1 0 0 1 1 1 1 Helix-hairpin-helix motif HHH PF00633.23 OQR89637.1 - 0.00032 20.4 0.0 0.00077 19.2 0.0 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix motif DUF655 PF04919.12 OQR89637.1 - 0.0004 20.4 0.2 0.0011 18.9 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF655) HHH_5 PF14520.6 OQR89637.1 - 0.0023 18.5 0.0 0.0073 16.9 0.0 1.9 1 0 0 1 1 1 1 Helix-hairpin-helix domain HHH_2 PF12826.7 OQR89637.1 - 0.022 14.8 0.0 0.094 12.8 0.0 2.0 2 0 0 2 2 2 0 Helix-hairpin-helix motif AAA_19 PF13245.6 OQR89637.1 - 0.026 14.8 0.0 0.1 12.9 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 OQR89637.1 - 0.051 14.0 0.0 0.47 10.8 0.0 2.5 2 1 0 2 2 2 0 AAA ATPase domain US10 PF17617.2 OQR89637.1 - 0.16 12.1 0.0 0.33 11.0 0.0 1.6 1 0 0 1 1 1 0 Viral unique short region 10 SKG6 PF08693.10 OQR89639.1 - 0.00015 21.1 2.8 0.00028 20.2 2.8 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Yip1 PF04893.17 OQR89639.1 - 0.02 14.6 0.0 0.034 13.9 0.0 1.3 1 0 0 1 1 1 0 Yip1 domain Sulf_transp PF04143.14 OQR89639.1 - 0.027 14.1 0.1 0.038 13.5 0.1 1.1 1 0 0 1 1 1 0 Sulphur transport Shisa PF13908.6 OQR89639.1 - 0.028 14.7 0.3 0.028 14.7 0.3 4.0 2 1 2 4 4 4 0 Wnt and FGF inhibitory regulator Adeno_E3_CR2 PF02439.15 OQR89639.1 - 0.29 10.9 1.8 0.52 10.1 1.8 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 ARTD15_N PF18084.1 OQR89639.1 - 1.6 9.0 7.7 0.35 11.2 0.8 3.1 3 0 0 3 3 3 0 ARTD15 N-terminal domain PP2C PF00481.21 OQR89641.1 - 1.2e-55 189.0 0.0 1.8e-55 188.4 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 OQR89641.1 - 0.0002 21.0 0.3 0.0015 18.2 0.3 2.4 1 1 0 1 1 1 1 Protein phosphatase 2C CRT-like PF08627.10 OQR89643.1 - 6.1e-50 170.0 17.4 1.9e-49 168.4 17.4 1.7 1 1 0 1 1 1 1 CRT-like, chloroquine-resistance transporter-like TMEM234 PF10639.9 OQR89643.1 - 0.007 16.4 0.2 0.02 14.9 0.2 1.7 1 0 0 1 1 1 1 Putative transmembrane family 234 EamA PF00892.20 OQR89643.1 - 0.0089 16.2 8.1 0.0089 16.2 8.1 4.4 3 1 1 4 4 4 2 EamA-like transporter family DUF2798 PF11391.8 OQR89643.1 - 0.24 11.5 6.5 0.21 11.6 3.5 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2798) Phage_holin_5_2 PF16079.5 OQR89643.1 - 2.6 8.4 8.3 7.7 6.9 0.9 4.0 4 0 0 4 4 4 0 Phage holin family Hol44, in holin superfamily V Pkinase PF00069.25 OQR89644.1 - 7.2e-48 163.2 0.0 1.4e-47 162.3 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQR89644.1 - 1.1e-25 90.4 0.0 1.8e-25 89.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 OQR89644.1 - 0.003 17.5 0.2 0.55 10.1 0.0 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kinase-like PF14531.6 OQR89644.1 - 0.011 15.1 0.0 0.019 14.3 0.0 1.5 1 0 0 1 1 1 0 Kinase-like RIO1 PF01163.22 OQR89644.1 - 0.027 14.1 0.1 4.8 6.7 0.0 2.3 2 0 0 2 2 2 0 RIO1 family BK_channel_a PF03493.18 OQR89645.1 - 1.5e-15 57.2 0.0 3e-15 56.2 0.0 1.6 1 0 0 1 1 1 1 Calcium-activated BK potassium channel alpha subunit Ion_trans PF00520.31 OQR89645.1 - 6.9e-14 51.7 8.0 1.6e-13 50.5 8.0 1.5 1 1 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 OQR89645.1 - 7.3e-11 41.9 0.8 7.3e-11 41.9 0.8 1.9 2 0 0 2 2 2 1 Ion channel TrkA_N PF02254.18 OQR89645.1 - 0.00038 20.7 0.2 0.26 11.6 0.0 2.7 2 0 0 2 2 2 2 TrkA-N domain Thioredoxin_8 PF13905.6 OQR89646.1 - 1.8e-23 82.7 0.0 2.2e-22 79.2 0.0 2.6 2 0 0 2 2 2 1 Thioredoxin-like Thioredoxin PF00085.20 OQR89646.1 - 9.8e-08 31.9 0.0 0.00035 20.5 0.0 2.6 1 1 1 2 2 2 2 Thioredoxin Thioredoxin_2 PF13098.6 OQR89646.1 - 1.8e-06 28.4 0.0 4.9e-06 27.0 0.0 1.7 1 0 0 1 1 1 1 Thioredoxin-like domain Redoxin PF08534.10 OQR89646.1 - 0.0023 17.7 0.0 0.0055 16.4 0.0 1.6 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 OQR89646.1 - 0.0028 17.6 0.0 0.0069 16.3 0.0 1.6 1 0 0 1 1 1 1 AhpC/TSA family Cellulase PF00150.18 OQR89648.1 - 2.6e-07 30.3 0.0 3.3e-07 30.0 0.0 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Peptidase_C1 PF00112.23 OQR89649.1 - 1.6e-98 329.1 18.8 2.2e-52 178.3 1.3 2.2 2 0 0 2 2 2 2 Papain family cysteine protease Peptidase_C1_2 PF03051.15 OQR89649.1 - 0.028 13.2 9.9 0.73 8.5 1.0 2.9 3 0 0 3 3 3 0 Peptidase C1-like family SPATA48 PF15073.6 OQR89649.1 - 0.17 12.2 0.0 13 6.1 0.0 2.3 2 0 0 2 2 2 0 Spermatogenesis-associated protein 48 Pyr_redox_2 PF07992.14 OQR89650.1 - 1.8e-38 132.5 0.0 3.7e-38 131.4 0.0 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 OQR89650.1 - 0.0022 18.5 0.1 0.0066 17.0 0.1 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DUF3445 PF11927.8 OQR89650.1 - 0.011 15.3 0.0 0.017 14.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3445) HA2 PF04408.23 OQR89652.1 - 1.2e-13 51.3 1.6 2.1e-13 50.5 1.6 1.4 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.31 OQR89652.1 - 1.9e-13 50.7 0.0 5.4e-13 49.2 0.0 1.8 1 1 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 OQR89652.1 - 7.8e-09 35.5 0.3 1.5e-08 34.6 0.3 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_19 PF13245.6 OQR89652.1 - 6.2e-05 23.4 0.3 0.00011 22.6 0.3 1.4 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 OQR89652.1 - 6.6e-05 23.2 1.0 0.0002 21.6 0.3 2.1 2 1 0 2 2 2 1 AAA domain SRP54 PF00448.22 OQR89652.1 - 0.00043 20.0 0.1 0.00065 19.4 0.1 1.4 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain Flavi_DEAD PF07652.14 OQR89652.1 - 0.00066 19.7 0.2 0.0013 18.7 0.2 1.5 1 0 0 1 1 1 1 Flavivirus DEAD domain ResIII PF04851.15 OQR89652.1 - 0.00079 19.5 0.1 0.0076 16.3 0.1 2.1 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_30 PF13604.6 OQR89652.1 - 0.0009 19.0 0.2 0.0014 18.3 0.2 1.3 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 OQR89652.1 - 0.0029 16.7 0.0 0.0056 15.8 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein ATPase PF06745.13 OQR89652.1 - 0.013 14.8 0.0 0.026 13.9 0.0 1.4 1 0 0 1 1 1 0 KaiC AAA_7 PF12775.7 OQR89652.1 - 0.021 14.3 0.0 0.037 13.6 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_14 PF13173.6 OQR89652.1 - 0.052 13.6 0.2 1.2 9.1 0.2 2.5 1 1 0 1 1 1 0 AAA domain AAA_33 PF13671.6 OQR89652.1 - 0.062 13.5 0.1 0.16 12.1 0.1 1.7 1 1 0 1 1 1 0 AAA domain DUF2075 PF09848.9 OQR89652.1 - 0.087 12.0 0.1 0.15 11.2 0.1 1.4 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Herpes_ori_bp PF02399.15 OQR89652.1 - 0.12 10.4 0.1 0.18 9.8 0.1 1.2 1 0 0 1 1 1 0 Origin of replication binding protein ABC_tran PF00005.27 OQR89652.1 - 0.19 12.3 0.2 1.7 9.2 0.2 2.2 1 1 0 1 1 1 0 ABC transporter Terminase_3 PF04466.13 OQR89652.1 - 0.2 11.1 0.0 0.31 10.5 0.0 1.3 1 0 0 1 1 1 0 Phage terminase large subunit OB_NTP_bind PF07717.16 OQR89654.1 - 5.4e-13 49.1 0.0 1.1e-12 48.1 0.0 1.5 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Peptidase_M91 PF14891.6 OQR89654.1 - 0.016 15.6 0.1 0.024 15.0 0.1 1.4 1 0 0 1 1 1 0 Effector protein Abhydrolase_1 PF00561.20 OQR89658.1 - 7e-11 42.3 0.1 5e-10 39.4 0.1 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 OQR89658.1 - 3.9e-10 39.4 0.0 5.4e-10 38.9 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 OQR89658.1 - 8.8e-05 23.2 0.0 0.00012 22.8 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.18 OQR89658.1 - 0.00078 19.1 0.0 0.0015 18.2 0.0 1.3 1 1 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Lipase_3 PF01764.25 OQR89658.1 - 0.015 15.2 0.1 0.027 14.3 0.1 1.5 1 0 0 1 1 1 0 Lipase (class 3) DUF1057 PF06342.12 OQR89658.1 - 0.015 14.4 0.0 0.025 13.6 0.0 1.4 1 1 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1057) LIDHydrolase PF10230.9 OQR89658.1 - 0.022 14.3 0.0 0.16 11.5 0.0 1.9 1 1 1 2 2 2 0 Lipid-droplet associated hydrolase FSH1 PF03959.13 OQR89658.1 - 0.089 12.4 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 Serine hydrolase (FSH1) PAF-AH_p_II PF03403.13 OQR89658.1 - 0.093 11.2 0.0 0.13 10.8 0.0 1.2 1 0 0 1 1 1 0 Platelet-activating factor acetylhydrolase, isoform II Glyco_trans_1_4 PF13692.6 OQR89659.1 - 0.00024 21.5 0.0 0.00059 20.3 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.20 OQR89659.1 - 0.00048 19.7 0.0 0.0012 18.4 0.0 1.6 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.20 OQR89660.1 - 1.5e-05 24.6 0.0 2.5e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 OQR89660.1 - 0.0031 17.9 0.0 0.0049 17.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Ufd2P_core PF10408.9 OQR89672.1 - 2.1e-159 532.1 2.6 2.7e-159 531.7 2.6 1.1 1 0 0 1 1 1 1 Ubiquitin elongating factor core U-box PF04564.15 OQR89672.1 - 4.2e-28 97.3 0.2 1.7e-27 95.4 0.2 2.1 1 0 0 1 1 1 1 U-box domain Glyco_hydro_72 PF03198.14 OQR89673.1 - 6.5e-44 150.5 0.5 1e-43 149.8 0.1 1.4 2 0 0 2 2 2 1 Glucanosyltransferase Aa_trans PF01490.18 OQR89673.1 - 5.7e-34 117.5 18.4 7.9e-34 117.0 18.4 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Cellulase PF00150.18 OQR89673.1 - 0.012 15.1 0.0 0.037 13.5 0.0 1.7 2 1 0 2 2 2 0 Cellulase (glycosyl hydrolase family 5) Aa_trans PF01490.18 OQR89676.1 - 2.7e-35 121.9 20.0 3.6e-35 121.5 20.0 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein EamA PF00892.20 OQR89679.1 - 3.2e-14 53.3 32.6 1.5e-08 34.9 12.8 2.1 2 0 0 2 2 2 2 EamA-like transporter family TPT PF03151.16 OQR89679.1 - 0.013 14.8 7.0 0.018 14.4 5.1 2.1 1 1 0 1 1 1 0 Triose-phosphate Transporter family Oxidored_FMN PF00724.20 OQR89680.1 - 1.1e-89 301.1 0.0 1.2e-89 300.9 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Ank_5 PF13857.6 OQR89681.1 - 3.2e-21 75.1 0.1 2.8e-06 27.5 0.0 4.2 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 OQR89681.1 - 4.3e-18 65.7 0.0 4e-15 56.2 0.0 2.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQR89681.1 - 1.1e-17 64.1 0.0 3.4e-06 27.5 0.0 3.3 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 OQR89681.1 - 7.3e-16 57.8 0.1 0.00028 21.2 0.0 4.2 4 0 0 4 4 4 3 Ankyrin repeat Ank_3 PF13606.6 OQR89681.1 - 3.6e-12 45.3 0.1 0.00026 21.2 0.0 4.1 4 1 0 4 4 4 2 Ankyrin repeat Iso_dh PF00180.20 OQR89682.1 - 0.47 9.5 3.0 0.5 9.4 3.0 1.1 1 0 0 1 1 1 0 Isocitrate/isopropylmalate dehydrogenase LYRIC PF15686.5 OQR89682.1 - 4.4 6.8 7.3 5.1 6.5 7.3 1.1 1 0 0 1 1 1 0 Lysine-rich CEACAM1 co-isolated protein family MIF4G PF02854.19 OQR89683.1 - 6.1e-44 150.2 3.1 1.1e-43 149.3 3.1 1.4 1 0 0 1 1 1 1 MIF4G domain MA3 PF02847.17 OQR89683.1 - 2.4e-10 40.4 0.8 9.5e-10 38.5 0.0 2.4 3 1 0 3 3 3 1 MA3 domain Dak2 PF02734.17 OQR89683.1 - 0.14 12.1 0.4 0.7 9.8 0.0 2.4 2 1 0 2 2 2 0 DAK2 domain Sld5 PF05916.11 OQR89683.1 - 0.31 11.5 2.1 1.4 9.4 0.1 2.6 2 1 0 2 2 2 0 GINS complex protein CPSF100_C PF13299.6 OQR89683.1 - 2.2 8.4 5.6 11 6.2 2.0 2.7 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal CH_2 PF06294.11 OQR89688.1 - 1e-18 67.2 0.0 5.5e-18 64.9 0.0 2.3 2 0 0 2 2 2 1 CH-like domain in sperm protein ADK PF00406.22 OQR89688.1 - 1.2e-13 51.4 0.2 1.3e-12 48.1 0.0 2.6 2 0 0 2 2 2 1 Adenylate kinase AAA_17 PF13207.6 OQR89688.1 - 0.00051 20.5 0.5 0.0022 18.4 0.0 2.4 2 0 0 2 2 2 1 AAA domain Hydin_ADK PF17213.3 OQR89688.1 - 0.045 14.0 0.0 0.045 14.0 0.0 3.9 3 1 0 3 3 3 0 Hydin Adenylate kinase-like domain Endonuc-HincII PF09226.11 OQR89689.1 - 0.021 14.2 0.0 0.039 13.2 0.0 1.5 1 0 0 1 1 1 0 Restriction endonuclease HincII ATP-synt_C PF00137.21 OQR89690.1 - 5.1e-28 97.2 30.6 2.5e-14 53.3 13.2 2.1 2 0 0 2 2 2 2 ATP synthase subunit C DUF1869 PF08956.10 OQR89690.1 - 0.051 13.5 0.0 0.096 12.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1869) GTP_EFTU PF00009.27 OQR89691.1 - 1.3e-52 178.1 0.1 2.1e-52 177.5 0.1 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain ChaC PF04752.12 OQR89691.1 - 5.6e-43 147.1 0.0 2.3e-42 145.1 0.0 1.9 2 0 0 2 2 2 1 ChaC-like protein EFG_C PF00679.24 OQR89691.1 - 1.2e-20 73.3 0.0 2.8e-20 72.1 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 OQR89691.1 - 2.3e-08 34.3 2.6 7.8e-08 32.6 2.6 2.0 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 OQR89691.1 - 1.7e-07 31.3 0.1 4.1e-07 30.1 0.1 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase GGACT PF06094.12 OQR89691.1 - 0.00031 21.3 0.0 0.00089 19.9 0.0 1.7 1 0 0 1 1 1 1 Gamma-glutamyl cyclotransferase, AIG2-like RsgA_GTPase PF03193.16 OQR89691.1 - 0.00058 19.8 0.0 0.12 12.3 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase SRPRB PF09439.10 OQR89691.1 - 0.0028 17.1 0.0 0.0062 16.0 0.0 1.5 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit FeoB_N PF02421.18 OQR89691.1 - 0.0035 16.9 0.1 0.027 14.0 0.1 2.4 1 1 0 1 1 1 1 Ferrous iron transport protein B EFG_II PF14492.6 OQR89691.1 - 0.0037 17.3 0.1 0.0083 16.2 0.1 1.5 1 0 0 1 1 1 1 Elongation Factor G, domain II AIG2_2 PF13772.6 OQR89691.1 - 0.0041 17.5 0.0 0.0084 16.5 0.0 1.5 1 0 0 1 1 1 1 AIG2-like family Septin PF00735.18 OQR89691.1 - 0.011 15.1 0.1 0.019 14.2 0.1 1.3 1 0 0 1 1 1 0 Septin Arf PF00025.21 OQR89691.1 - 0.062 12.8 0.0 0.21 11.0 0.0 1.9 1 1 0 1 1 1 0 ADP-ribosylation factor family Roc PF08477.13 OQR89691.1 - 0.072 13.3 0.0 0.14 12.4 0.0 1.5 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase PT PF04886.12 OQR89696.1 - 1.7e-13 49.8 36.2 9.5e-09 34.7 16.6 2.8 2 1 1 3 3 3 2 PT repeat DUF4106 PF13388.6 OQR89696.1 - 0.0095 15.2 7.5 0.013 14.7 7.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4106) Trypan_PARP PF05887.11 OQR89696.1 - 4.1 7.4 19.9 5.7 6.9 19.9 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Ribosomal_S19 PF00203.21 OQR89705.1 - 1.8e-32 111.1 0.1 2.5e-32 110.6 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein S19 LCAT PF02450.15 OQR89705.1 - 0.13 11.4 0.0 0.17 11.0 0.0 1.1 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase IQ PF00612.27 OQR89706.1 - 4.7e-21 72.6 75.8 2.7e-05 23.6 0.4 13.0 12 0 0 12 12 12 9 IQ calmodulin-binding motif p25-alpha PF05517.12 OQR89706.1 - 0.00024 21.3 0.0 0.00078 19.6 0.0 1.9 1 0 0 1 1 1 1 p25-alpha Intg_mem_TP0381 PF09529.10 OQR89706.1 - 0.075 12.5 1.7 0.09 12.3 0.0 1.9 2 0 0 2 2 2 0 Integral membrane protein (intg_mem_TP0381) Atypical_Card PF18461.1 OQR89706.1 - 1.6 9.0 3.9 43 4.4 0.1 3.1 2 0 0 2 2 2 0 Atypical caspase recruitment domain Ank_2 PF12796.7 OQR89707.1 - 4.6e-33 113.7 0.4 1.1e-11 45.1 0.0 3.8 4 0 0 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQR89707.1 - 1.9e-28 98.5 4.8 3.5e-08 33.8 0.0 5.4 2 2 3 5 5 5 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 OQR89707.1 - 5.6e-28 96.6 3.9 1.5e-09 37.9 0.5 4.5 3 3 2 5 5 5 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQR89707.1 - 6.2e-26 87.6 0.5 2.4e-05 24.4 0.0 7.6 7 0 0 7 7 7 4 Ankyrin repeat Ank PF00023.30 OQR89707.1 - 1.4e-25 88.5 6.6 6.9e-07 29.4 0.0 6.3 5 1 0 5 5 5 3 Ankyrin repeat Ribosomal_L10 PF00466.20 OQR89707.1 - 8.7e-22 77.1 0.2 2.5e-21 75.7 0.0 1.8 2 0 0 2 2 2 1 Ribosomal protein L10 RL10P_insert PF17777.1 OQR89707.1 - 3.1e-20 72.0 0.1 7.6e-20 70.7 0.1 1.7 1 0 0 1 1 1 1 Insertion domain in 60S ribosomal protein L10P Ribosomal_60s PF00428.19 OQR89707.1 - 1e-09 38.9 9.0 2.2e-09 37.8 9.0 1.6 1 0 0 1 1 1 1 60s Acidic ribosomal protein DAGAT PF03982.13 OQR89708.1 - 4.2e-05 22.6 0.1 6.4e-05 22.0 0.1 1.3 1 1 0 1 1 1 1 Diacylglycerol acyltransferase Acyltransferase PF01553.21 OQR89708.1 - 0.016 14.8 0.0 0.34 10.5 0.0 2.2 1 1 0 1 1 1 0 Acyltransferase Pkinase PF00069.25 OQR89709.1 - 1.7e-105 352.1 0.0 7e-53 179.7 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OQR89709.1 - 9.1e-104 346.3 0.0 3.2e-52 177.4 0.0 2.4 2 0 0 2 2 2 2 Protein tyrosine kinase Glyco_hydro_18 PF00704.28 OQR89709.1 - 1.7e-70 238.2 0.1 2.4e-70 237.7 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Pkinase_fungal PF17667.1 OQR89709.1 - 2.3e-08 33.3 0.0 0.0033 16.2 0.0 2.2 2 0 0 2 2 2 2 Fungal protein kinase Kinase-like PF14531.6 OQR89709.1 - 2.7e-08 33.5 0.0 0.00046 19.6 0.0 2.4 2 0 0 2 2 2 2 Kinase-like FTA2 PF13095.6 OQR89709.1 - 0.00019 21.1 0.1 4.3 6.9 0.0 4.0 4 0 0 4 4 4 2 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 OQR89709.1 - 0.00028 20.3 0.1 0.8 9.0 0.0 2.4 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OQR89709.1 - 0.00044 20.3 0.1 0.41 10.5 0.0 2.5 2 0 0 2 2 2 2 Phosphotransferase enzyme family DUF587 PF04532.12 OQR89709.1 - 0.005 16.1 0.1 0.011 15.0 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF587) Nitrate_red_gam PF02665.14 OQR89709.1 - 0.0054 16.3 0.7 0.014 14.9 0.0 2.0 2 0 0 2 2 2 1 Nitrate reductase gamma subunit Haspin_kinase PF12330.8 OQR89709.1 - 0.012 14.6 0.1 1.6 7.6 0.0 2.3 2 0 0 2 2 2 0 Haspin like kinase domain Arm_vescicular PF18770.1 OQR89709.1 - 0.12 12.3 0.2 0.94 9.5 0.0 2.6 2 1 1 3 3 3 0 Armadillo tether-repeat of vescicular transport factor Choline_transpo PF04515.12 OQR89710.1 - 3.3e-58 197.4 29.7 3.3e-58 197.4 29.7 5.3 5 3 0 5 5 5 1 Plasma-membrane choline transporter cNMP_binding PF00027.29 OQR89710.1 - 5.5e-50 167.4 0.0 4e-15 55.7 0.0 5.1 5 0 0 5 5 5 4 Cyclic nucleotide-binding domain Ion_trans PF00520.31 OQR89710.1 - 3.7e-21 75.5 93.7 4.1e-11 42.6 7.9 6.8 6 1 0 6 6 6 4 Ion transport protein Ion_trans_2 PF07885.16 OQR89710.1 - 7.6e-12 45.0 43.8 6.8e-06 26.0 4.6 5.9 5 0 0 5 5 5 3 Ion channel DAGAT PF03982.13 OQR89711.1 - 5.1e-05 22.3 0.0 0.00021 20.3 0.0 1.7 1 1 1 2 2 2 1 Diacylglycerol acyltransferase SLATT_fungal PF18142.1 OQR89712.1 - 8.6 6.4 6.6 0.75 9.8 1.4 1.8 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain T6SS_Vgr PF13296.6 OQR89715.1 - 0.008 16.3 1.5 0.83 9.8 0.2 2.3 1 1 1 2 2 2 2 Putative type VI secretion system Rhs element Vgr FAD_binding_4 PF01565.23 OQR89723.1 - 9.4e-16 57.8 0.1 1.5e-15 57.2 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain Na_H_antiporter PF03553.14 OQR89724.1 - 1.5e-39 136.0 9.9 1.5e-39 136.0 9.9 3.1 1 1 1 2 2 2 1 Na+/H+ antiporter family KIAA1430 PF13879.6 OQR89724.1 - 4.4e-09 37.0 13.5 4.4e-09 37.0 13.5 2.5 1 1 1 2 2 2 1 KIAA1430 homologue Lung_7-TM_R PF06814.13 OQR89725.1 - 0.66 9.2 41.2 0.0076 15.5 23.9 3.1 2 2 0 2 2 2 0 Lung seven transmembrane receptor PhoLip_ATPase_N PF16209.5 OQR89725.1 - 0.86 9.3 5.0 7.4 6.3 0.9 3.1 2 0 0 2 2 2 0 Phospholipid-translocating ATPase N-terminal F-box PF00646.33 OQR89727.1 - 0.00018 21.3 0.0 0.00072 19.4 0.0 2.0 2 0 0 2 2 2 1 F-box domain FPP PF05911.11 OQR89727.1 - 0.00034 19.0 16.0 0.00034 19.0 16.0 2.2 2 0 0 2 2 2 2 Filament-like plant protein, long coiled-coil MAD PF05557.13 OQR89727.1 - 0.0043 15.5 12.3 0.0043 15.5 12.3 2.3 2 0 0 2 2 2 1 Mitotic checkpoint protein Flp_N PF03930.14 OQR89727.1 - 0.0057 16.6 2.6 0.065 13.2 0.4 2.6 2 0 0 2 2 2 1 Recombinase Flp protein N-terminus F-box-like PF12937.7 OQR89727.1 - 0.011 15.6 0.0 0.025 14.5 0.0 1.6 1 0 0 1 1 1 0 F-box-like CD4-extracel PF09191.10 OQR89727.1 - 0.033 14.6 0.7 0.1 13.0 0.7 1.8 1 0 0 1 1 1 0 CD4, extracellular ArsR PF09824.9 OQR89727.1 - 0.12 12.0 5.9 0.55 9.8 0.8 2.6 2 0 0 2 2 2 0 ArsR transcriptional regulator HXXSHH PF07586.11 OQR89727.1 - 0.21 11.2 5.7 0.44 10.1 5.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1552) Prefoldin_2 PF01920.20 OQR89727.1 - 0.85 9.6 31.5 3.2 7.7 8.7 4.7 3 1 1 4 4 4 0 Prefoldin subunit Med10 PF09748.9 OQR89727.1 - 1 9.3 8.9 4 7.4 0.0 3.4 3 0 0 3 3 3 0 Transcription factor subunit Med10 of Mediator complex USP8_interact PF08941.10 OQR89727.1 - 2.8 7.7 12.4 0.31 10.9 0.1 3.4 2 1 0 3 3 3 0 USP8 interacting KELK PF15796.5 OQR89727.1 - 3.5 8.1 37.4 1.7 9.1 7.7 5.1 2 2 3 5 5 5 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase NPV_P10 PF05531.12 OQR89727.1 - 3.8 8.0 7.5 12 6.5 0.6 3.7 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein UIM PF02809.20 OQR89727.1 - 5.2 7.2 7.3 0.97 9.5 1.5 3.0 2 0 0 2 2 2 0 Ubiquitin interaction motif bZIP_1 PF00170.21 OQR89727.1 - 7.1 6.8 25.4 0.75 9.9 1.1 4.9 4 0 0 4 4 4 0 bZIP transcription factor Hist_deacetyl PF00850.19 OQR89728.1 - 1.8e-63 214.9 0.1 2.7e-63 214.3 0.1 1.2 1 0 0 1 1 1 1 Histone deacetylase domain Ank_4 PF13637.6 OQR89728.1 - 5.4e-13 49.2 2.1 1.6e-07 31.7 0.3 3.5 2 1 0 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 OQR89728.1 - 6.4e-12 45.5 0.4 3.6e-07 30.3 0.1 4.5 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 OQR89728.1 - 1.2e-11 45.0 1.8 1.1e-05 25.9 0.4 3.7 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OQR89728.1 - 1.8e-11 43.2 2.3 0.093 13.3 0.0 5.6 5 0 0 5 5 5 3 Ankyrin repeat Ank PF00023.30 OQR89728.1 - 1.5e-08 34.7 5.0 0.0067 16.8 0.2 4.9 5 0 0 5 5 5 2 Ankyrin repeat Ank_2 PF12796.7 OQR89729.1 - 1.9e-47 159.8 16.3 2.8e-12 47.1 0.9 7.7 3 2 5 8 8 8 8 Ankyrin repeats (3 copies) Ank PF00023.30 OQR89729.1 - 3.2e-36 122.2 34.3 0.0014 18.9 0.1 12.1 12 0 0 12 12 12 11 Ankyrin repeat Ank_4 PF13637.6 OQR89729.1 - 6.6e-36 122.2 19.6 5.7e-10 39.5 0.4 10.5 7 3 4 11 11 11 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQR89729.1 - 8.4e-36 117.9 27.4 0.00051 20.3 0.1 13.2 14 0 0 14 14 14 10 Ankyrin repeat Ank_5 PF13857.6 OQR89729.1 - 1.1e-34 118.0 19.1 1.7e-05 25.0 0.0 10.5 6 4 5 11 11 11 9 Ankyrin repeats (many copies) FYVE PF01363.21 OQR89731.1 - 7.6e-14 51.6 8.5 7.6e-14 51.6 8.5 2.1 2 1 0 2 2 2 1 FYVE zinc finger zf-C2HC5 PF06221.13 OQR89731.1 - 0.1 12.6 3.8 0.29 11.2 3.8 1.7 1 0 0 1 1 1 0 Putative zinc finger motif, C2HC5-type FYVE_2 PF02318.16 OQR89731.1 - 2.7 8.2 10.7 2.8 8.2 8.8 2.0 1 1 1 2 2 2 0 FYVE-type zinc finger SNARE PF05739.19 OQR89732.1 - 1.1e-11 44.6 0.1 1.1e-11 44.6 0.1 1.9 2 0 0 2 2 2 1 SNARE domain Syntaxin PF00804.25 OQR89732.1 - 0.0025 17.5 7.1 0.25 11.0 0.2 2.2 2 0 0 2 2 2 2 Syntaxin SLATT_5 PF18160.1 OQR89732.1 - 0.067 12.5 0.1 0.11 11.8 0.1 1.4 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain family 5 DUF2207 PF09972.9 OQR89732.1 - 0.079 11.7 1.2 2.8 6.6 0.1 2.3 1 1 2 3 3 3 0 Predicted membrane protein (DUF2207) Syntaxin-6_N PF09177.11 OQR89732.1 - 0.42 11.2 4.9 0.14 12.7 0.6 2.3 2 2 0 2 2 2 0 Syntaxin 6, N-terminal Glyco_transf_41 PF13844.6 OQR89733.1 - 5.7e-12 44.8 0.1 5.4e-10 38.3 0.1 2.2 2 0 0 2 2 2 2 Glycosyl transferase family 41 PA PF02225.22 OQR89733.1 - 0.0025 17.8 0.0 0.0046 17.0 0.0 1.4 1 0 0 1 1 1 1 PA domain DUF4817 PF16087.5 OQR89733.1 - 0.02 14.7 1.4 0.029 14.2 0.1 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain (DUF4817) Pkinase PF00069.25 OQR89734.1 - 1.2e-67 228.0 0.0 1.6e-67 227.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQR89734.1 - 3.9e-31 108.3 0.0 5.8e-31 107.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OQR89734.1 - 2.4e-07 30.4 0.1 8.5e-06 25.3 0.0 2.2 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 OQR89734.1 - 1.1e-05 24.9 0.2 2.9e-05 23.5 0.2 1.6 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 OQR89734.1 - 2.1e-05 24.2 0.0 3.8e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 RIO1 family Haspin_kinase PF12330.8 OQR89734.1 - 0.0002 20.4 0.0 0.00036 19.6 0.0 1.4 1 0 0 1 1 1 1 Haspin like kinase domain Myb_DNA-binding PF00249.31 OQR89734.1 - 0.00028 21.0 0.1 0.0011 19.2 0.1 2.0 2 0 0 2 2 2 1 Myb-like DNA-binding domain Seadorna_VP7 PF07387.11 OQR89734.1 - 0.14 11.2 0.0 0.23 10.5 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 CBM_1 PF00734.18 OQR89737.1 - 3.6e-13 49.2 23.8 2.9e-12 46.3 6.3 4.2 3 1 0 3 3 3 2 Fungal cellulose binding domain HOCHOB PF17943.1 OQR89737.1 - 1.8 9.3 4.6 21 5.9 0.4 2.3 2 0 0 2 2 2 0 Homeobox-cysteine loop-homeobox PX PF00787.24 OQR89738.1 - 1.6e-07 31.3 0.1 2.5e-07 30.7 0.1 1.2 1 0 0 1 1 1 1 PX domain PX PF00787.24 OQR89739.1 - 9.1e-13 48.2 0.0 0.00047 20.1 0.0 3.5 3 1 1 4 4 4 3 PX domain Myosin_head PF00063.21 OQR89740.1 - 3.2e-130 435.5 0.1 4.9e-130 434.8 0.1 1.3 1 0 0 1 1 1 1 Myosin head (motor domain) PX PF00787.24 OQR89740.1 - 3.9e-11 42.9 0.3 1.3e-10 41.3 0.3 1.9 1 0 0 1 1 1 1 PX domain IQ PF00612.27 OQR89740.1 - 0.0015 18.1 19.5 0.018 14.8 1.9 4.0 3 0 0 3 3 3 3 IQ calmodulin-binding motif ZapB PF06005.12 OQR89740.1 - 2.3 8.7 13.3 0.49 10.9 8.7 2.3 2 0 0 2 2 2 0 Cell division protein ZapB YabA PF06156.13 OQR89740.1 - 6.4 7.5 8.0 38 5.0 5.5 3.1 2 1 1 3 3 3 0 Initiation control protein YabA Myosin_head PF00063.21 OQR89741.1 - 5.3e-52 177.0 0.3 7.8e-52 176.4 0.3 1.3 1 0 0 1 1 1 1 Myosin head (motor domain) PX PF00787.24 OQR89741.1 - 7e-12 45.3 1.2 1.7e-11 44.1 0.4 2.1 2 0 0 2 2 2 1 PX domain IQ PF00612.27 OQR89741.1 - 5.3e-09 35.1 17.4 0.00055 19.5 0.7 4.2 3 0 0 3 3 3 3 IQ calmodulin-binding motif HALZ PF02183.18 OQR89741.1 - 0.36 11.1 6.5 1.3 9.3 1.8 3.0 3 0 0 3 3 3 0 Homeobox associated leucine zipper 6PGD PF00393.19 OQR89745.1 - 1.9e-126 421.3 0.0 2.3e-126 421.0 0.0 1.1 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.15 OQR89745.1 - 2.5e-45 154.5 0.0 3.6e-45 154.0 0.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 3HCDH_N PF02737.18 OQR89745.1 - 0.0081 16.1 0.0 0.016 15.1 0.0 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain F420_oxidored PF03807.17 OQR89745.1 - 0.014 15.9 0.0 0.03 14.9 0.0 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent SPRY PF00622.28 OQR89746.1 - 3.7e-18 65.8 0.0 5.7e-18 65.2 0.0 1.3 1 0 0 1 1 1 1 SPRY domain TGT PF01702.18 OQR89747.1 - 7.6e-138 459.4 0.0 1e-137 459.0 0.0 1.1 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase CIA30 PF08547.12 OQR89747.1 - 1.8e-34 119.0 0.0 2.9e-34 118.4 0.0 1.3 1 0 0 1 1 1 1 Complex I intermediate-associated protein 30 (CIA30) YgbA_NO PF11756.8 OQR89747.1 - 0.068 13.5 0.4 0.28 11.5 0.1 2.0 2 0 0 2 2 2 0 Nitrous oxide-stimulated promoter Glu-tRNAGln PF02686.15 OQR89747.1 - 0.17 12.2 0.1 0.43 10.9 0.1 1.6 1 0 0 1 1 1 0 Glu-tRNAGln amidotransferase C subunit Trm112p PF03966.16 OQR89748.1 - 1e-10 42.1 0.0 1.1e-10 41.9 0.0 1.1 1 0 0 1 1 1 1 Trm112p-like protein BT1 PF03092.16 OQR89749.1 - 4.4e-11 41.7 1.2 4.4e-11 41.7 1.2 3.3 2 1 1 3 3 3 3 BT1 family PUCC PF03209.15 OQR89749.1 - 0.00022 20.4 6.3 0.00062 18.9 0.3 2.5 2 0 0 2 2 2 2 PUCC protein Dicer_N PF17895.1 OQR89749.1 - 0.032 14.1 0.0 0.065 13.1 0.0 1.4 1 0 0 1 1 1 0 Giardia Dicer N-terminal domain Phage_holin_3_6 PF07332.11 OQR89749.1 - 0.16 12.0 0.0 0.16 12.0 0.0 3.5 4 0 0 4 4 4 0 Putative Actinobacterial Holin-X, holin superfamily III Cupin_4 PF08007.12 OQR89750.1 - 3.3e-12 46.5 1.1 7.7e-11 42.0 1.1 2.7 1 1 0 1 1 1 1 Cupin superfamily protein Cupin_8 PF13621.6 OQR89750.1 - 1.6e-10 41.1 0.0 2.9e-10 40.3 0.0 1.4 1 0 0 1 1 1 1 Cupin-like domain Cupin_2 PF07883.11 OQR89750.1 - 0.0047 16.6 0.0 0.051 13.3 0.0 2.5 3 0 0 3 3 3 1 Cupin domain AKNA PF12443.8 OQR89750.1 - 0.0058 17.2 0.1 0.016 15.8 0.1 1.7 1 0 0 1 1 1 1 AT-hook-containing transcription factor DUF2205 PF10224.9 OQR89750.1 - 0.014 15.4 0.1 0.029 14.3 0.1 1.5 1 0 0 1 1 1 0 Short coiled-coil protein V-SNARE PF05008.15 OQR89750.1 - 0.027 14.8 0.3 2.5 8.6 0.1 2.3 2 0 0 2 2 2 0 Vesicle transport v-SNARE protein N-terminus Dimerisation PF08100.11 OQR89750.1 - 0.091 12.8 0.2 0.21 11.7 0.2 1.6 1 0 0 1 1 1 0 Dimerisation domain RED_N PF07808.13 OQR89751.1 - 1.8e-15 57.2 0.6 1.6e-12 47.5 0.0 4.2 3 1 1 4 4 4 3 RED-like protein N-terminal region Mid2 PF04478.12 OQR89756.1 - 0.11 12.4 0.0 0.21 11.4 0.0 1.5 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor LOR PF04525.12 OQR89756.1 - 0.13 11.9 0.0 0.23 11.0 0.0 1.5 1 0 0 1 1 1 0 LURP-one-related zf-C2H2 PF00096.26 OQR89757.1 - 1.6e-27 94.4 52.3 1e-05 25.7 0.2 8.2 8 0 0 8 8 8 7 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 OQR89757.1 - 2.2e-22 77.8 52.2 0.00068 20.3 0.1 8.2 8 0 0 8 8 8 7 C2H2-type zinc finger zf-H2C2_2 PF13465.6 OQR89757.1 - 3e-16 59.0 34.3 0.0092 16.4 0.1 9.2 9 1 0 9 9 9 5 Zinc-finger double domain zf-C2H2_6 PF13912.6 OQR89757.1 - 1.7e-06 27.9 38.4 0.013 15.5 0.0 7.8 9 0 0 9 9 8 3 C2H2-type zinc finger zf-Di19 PF05605.12 OQR89757.1 - 0.00014 22.1 14.6 0.00062 20.0 3.3 5.7 4 2 1 5 5 5 3 Drought induced 19 protein (Di19), zinc-binding zf-met PF12874.7 OQR89757.1 - 0.001 19.3 1.1 0.0043 17.4 0.6 7.2 7 0 0 7 7 7 2 Zinc-finger of C2H2 type zf-C2H2_8 PF15909.5 OQR89757.1 - 0.002 18.4 30.9 0.019 15.2 3.3 4.7 2 2 3 5 5 5 2 C2H2-type zinc ribbon zf_UBZ PF18439.1 OQR89757.1 - 0.0075 15.8 13.1 2.7 7.7 0.1 5.0 5 0 0 5 5 5 2 Ubiquitin-Binding Zinc Finger zf-H2C2_5 PF13909.6 OQR89757.1 - 0.017 14.9 32.5 1.8 8.4 0.4 7.1 7 0 0 7 7 6 0 C2H2-type zinc-finger domain Sprouty PF05210.13 OQR89757.1 - 0.02 15.2 0.5 0.02 15.2 0.5 3.0 2 1 0 2 2 2 0 Sprouty protein (Spry) zf-C2H2_9 PF16293.5 OQR89757.1 - 0.043 13.7 0.2 0.043 13.7 0.2 4.4 6 0 0 6 6 5 0 C2H2 type zinc-finger (1 copy) IBR PF01485.21 OQR89757.1 - 0.14 12.4 0.2 0.14 12.4 0.2 4.3 1 1 3 4 4 3 0 IBR domain, a half RING-finger domain zf-C2H2_jaz PF12171.8 OQR89757.1 - 0.17 12.2 0.2 0.17 12.2 0.2 6.1 7 0 0 7 7 6 0 Zinc-finger double-stranded RNA-binding zf-C2H2_11 PF16622.5 OQR89757.1 - 0.36 10.6 32.4 0.95 9.3 0.0 7.5 8 0 0 8 8 8 0 zinc-finger C2H2-type zf_C2H2_ZHX PF18387.1 OQR89757.1 - 0.45 10.2 0.1 0.45 10.2 0.1 5.9 4 2 3 7 7 7 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-C2H2_3rep PF18868.1 OQR89757.1 - 0.7 10.6 25.7 3.6 8.3 0.3 5.6 2 1 2 4 4 4 0 Zinc finger C2H2-type, 3 repeats zinc_ribbon_15 PF17032.5 OQR89757.1 - 0.84 10.4 23.0 2.2 9.1 1.6 4.4 2 1 3 5 5 5 0 zinc-ribbon family DZR PF12773.7 OQR89757.1 - 1.4 9.0 28.0 1.7e+02 2.3 6.8 4.1 2 2 0 2 2 2 0 Double zinc ribbon zf-CCHC_2 PF13696.6 OQR89757.1 - 2.1 8.2 7.5 2.4 8.1 0.4 3.6 3 0 0 3 3 3 0 Zinc knuckle FOXP-CC PF16159.5 OQR89757.1 - 2.7 8.7 25.7 12 6.7 0.4 6.2 3 2 3 6 6 6 0 FOXP coiled-coil domain CpXC PF14353.6 OQR89757.1 - 4.4 7.4 22.7 1.7 8.7 0.8 4.7 2 2 1 3 3 3 0 CpXC protein ROS_MUCR PF05443.11 OQR89757.1 - 4.6 7.3 5.6 20 5.3 0.2 3.2 2 2 1 3 3 3 0 ROS/MUCR transcriptional regulator protein ADK_lid PF05191.14 OQR89757.1 - 5.6 7.0 23.3 0.45 10.5 3.1 4.8 4 2 0 4 4 4 0 Adenylate kinase, active site lid OSCP PF00213.18 OQR89758.1 - 2.8e-45 154.5 3.7 3.3e-45 154.3 3.7 1.0 1 0 0 1 1 1 1 ATP synthase delta (OSCP) subunit Sec5 PF15469.6 OQR89758.1 - 0.035 13.9 0.3 0.044 13.6 0.3 1.1 1 0 0 1 1 1 0 Exocyst complex component Sec5 ABC_tran_CTD PF16326.5 OQR89758.1 - 1.1 9.6 4.1 3.4 8.0 0.3 2.5 2 0 0 2 2 2 0 ABC transporter C-terminal domain FA_desaturase PF00487.24 OQR89759.1 - 1.2e-12 48.2 21.3 2.7e-12 47.1 21.3 1.5 1 1 0 1 1 1 1 Fatty acid desaturase RNase_PH PF01138.21 OQR89760.1 - 1.8e-19 70.6 0.4 4e-18 66.2 0.0 2.4 2 0 0 2 2 2 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 OQR89760.1 - 7.8e-08 32.2 0.4 4.7e-07 29.7 0.0 2.3 2 0 0 2 2 2 1 3' exoribonuclease family, domain 2 DUF812 PF05667.11 OQR89761.1 - 2.2e-90 304.3 24.8 3.7e-89 300.2 24.8 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF812) Lebercilin PF15619.6 OQR89761.1 - 0.018 14.7 1.7 0.018 14.7 1.7 4.2 2 1 2 4 4 4 0 Ciliary protein causing Leber congenital amaurosis disease DotD PF16816.5 OQR89761.1 - 0.032 14.2 0.5 0.074 13.0 0.5 1.7 1 0 0 1 1 1 0 DotD protein TPD52 PF04201.15 OQR89761.1 - 0.13 11.9 3.8 0.076 12.6 1.5 1.9 2 0 0 2 2 2 0 Tumour protein D52 family RasGEF_N PF00618.20 OQR89761.1 - 0.15 12.4 0.5 1.8 8.8 0.1 2.7 2 1 0 2 2 2 0 RasGEF N-terminal motif Cauli_DNA-bind PF03310.13 OQR89761.1 - 9 6.4 8.9 9.4 6.3 5.6 2.7 2 1 0 2 2 2 0 Caulimovirus DNA-binding protein BT1 PF03092.16 OQR89762.1 - 1.2e-12 46.9 10.0 8.7e-11 40.7 1.0 3.1 3 0 0 3 3 3 3 BT1 family PUCC PF03209.15 OQR89762.1 - 0.00019 20.6 0.4 0.00019 20.6 0.4 2.3 3 0 0 3 3 3 1 PUCC protein MACPF PF01823.19 OQR89769.1 - 0.0027 17.9 0.7 0.0068 16.5 0.7 1.6 1 1 0 1 1 1 1 MAC/Perforin domain DUF4808 PF16066.5 OQR89770.1 - 0.24 11.9 0.3 0.32 11.6 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4808) Peptidase_M41 PF01434.18 OQR89771.1 - 2.5e-62 210.1 0.2 4.5e-62 209.3 0.0 1.5 2 0 0 2 2 1 1 Peptidase family M41 AAA PF00004.29 OQR89771.1 - 1.7e-42 145.0 0.0 3.7e-42 143.9 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 OQR89771.1 - 3.4e-15 55.6 0.1 9.8e-15 54.1 0.1 1.8 1 0 0 1 1 1 1 AAA+ lid domain AAA_22 PF13401.6 OQR89771.1 - 0.00016 22.0 0.0 0.13 12.5 0.0 2.8 2 0 0 2 2 2 2 AAA domain FtsH_ext PF06480.15 OQR89771.1 - 0.00031 21.1 0.0 0.0012 19.1 0.0 2.0 1 1 0 1 1 1 1 FtsH Extracellular AAA_5 PF07728.14 OQR89771.1 - 0.00031 20.8 0.0 0.0027 17.7 0.0 2.6 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) TIP49 PF06068.13 OQR89771.1 - 0.0021 17.3 1.1 0.0028 16.9 0.1 1.7 2 0 0 2 2 2 1 TIP49 P-loop domain AAA_2 PF07724.14 OQR89771.1 - 0.0031 17.6 0.0 0.016 15.4 0.0 2.2 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) Mg_chelatase PF01078.21 OQR89771.1 - 0.007 15.8 0.0 0.019 14.4 0.1 1.6 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI RuvB_N PF05496.12 OQR89771.1 - 0.0079 16.0 0.0 0.019 14.7 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 OQR89771.1 - 0.015 15.7 0.2 0.21 12.0 0.1 2.4 1 1 1 2 2 2 0 AAA ATPase domain IstB_IS21 PF01695.17 OQR89771.1 - 0.026 14.2 0.0 0.063 13.0 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_14 PF13173.6 OQR89771.1 - 0.03 14.4 0.0 0.094 12.7 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.6 OQR89771.1 - 0.038 14.4 0.1 0.59 10.6 0.0 2.9 3 0 0 3 3 2 0 AAA domain AAA_33 PF13671.6 OQR89771.1 - 0.058 13.5 0.0 0.15 12.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 OQR89771.1 - 0.067 12.7 0.0 0.27 10.7 0.0 1.8 2 0 0 2 2 2 0 P-loop containing dynein motor region WW PF00397.26 OQR89773.1 - 1.1e-11 44.6 0.5 0.00022 21.2 0.1 2.7 2 0 0 2 2 2 2 WW domain zf-C3HC4_3 PF13920.6 OQR89773.1 - 5.1 7.0 18.6 9.3 6.2 8.1 3.0 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) DZR PF12773.7 OQR89773.1 - 5.2 7.2 16.7 6.8 6.8 7.5 3.2 2 1 1 3 3 3 0 Double zinc ribbon Metallophos PF00149.28 OQR89778.1 - 1.6e-08 35.3 4.1 4.7e-08 33.8 4.1 1.8 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Corona_M PF01635.18 OQR89785.1 - 0.082 12.2 1.2 0.11 11.7 0.1 1.7 2 0 0 2 2 2 0 Coronavirus M matrix/glycoprotein Ipi1_N PF12333.8 OQR89788.1 - 3.8e-08 33.9 4.9 1.3e-06 28.9 0.5 4.7 3 1 0 3 3 3 1 Rix1 complex component involved in 60S ribosome maturation HEAT_EZ PF13513.6 OQR89788.1 - 0.0053 17.2 0.6 0.035 14.6 0.6 2.6 1 0 0 1 1 1 1 HEAT-like repeat DUF1712 PF08217.11 OQR89790.1 - 9.7e-12 44.2 0.0 1.5e-11 43.5 0.0 1.2 1 0 0 1 1 1 1 Fungal domain of unknown function (DUF1712) Sugar_tr PF00083.24 OQR89791.1 - 5.5e-25 88.1 11.4 6e-25 88.0 11.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OQR89791.1 - 6e-06 25.4 11.8 1.3e-05 24.3 11.8 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF5325 PF17259.2 OQR89791.1 - 0.028 14.3 1.1 0.06 13.2 1.1 1.6 1 1 0 1 1 1 0 Family of unknown function (DUF5325) HlyIII PF03006.20 OQR89791.1 - 0.06 13.1 6.5 0.12 12.1 6.5 1.6 1 1 0 1 1 1 0 Haemolysin-III related DUF4407 PF14362.6 OQR89791.1 - 0.36 10.2 0.9 0.58 9.5 0.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Sigma_reg_N PF13800.6 OQR89791.1 - 2 8.8 4.1 4.1 7.8 1.0 2.5 2 1 1 3 3 3 0 Sigma factor regulator N-terminal Sugar_tr PF00083.24 OQR89792.1 - 4.3e-50 170.9 9.9 5.4e-50 170.6 9.9 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OQR89792.1 - 3.5e-15 55.8 13.2 6.9e-15 54.8 12.8 1.6 1 1 1 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 OQR89792.1 - 6.7e-05 21.5 3.0 9.4e-05 21.0 3.0 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_5 PF05631.14 OQR89792.1 - 0.0027 16.7 0.6 0.0078 15.2 0.4 1.8 2 0 0 2 2 2 1 Sugar-tranasporters, 12 TM Pro_isomerase PF00160.21 OQR89794.1 - 4.8e-50 169.9 0.4 5.4e-50 169.7 0.4 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD NYD-SP28_assoc PF14775.6 OQR89795.1 - 3.8e-16 58.9 1.1 3.8e-16 58.9 1.1 5.7 4 1 2 6 6 6 1 Sperm tail C-terminal domain Syntaxin-6_N PF09177.11 OQR89795.1 - 0.22 12.1 14.7 1.2 9.7 4.1 3.0 1 1 1 2 2 2 0 Syntaxin 6, N-terminal Myb_DNA-bind_4 PF13837.6 OQR89795.1 - 0.87 10.0 8.0 2 8.9 6.6 2.4 1 1 1 2 2 2 0 Myb/SANT-like DNA-binding domain ZnuA PF01297.17 OQR89795.1 - 1.4 8.2 5.8 4 6.8 5.8 1.8 1 0 0 1 1 1 0 Zinc-uptake complex component A periplasmic Atg14 PF10186.9 OQR89795.1 - 1.9 7.5 17.3 3.7 6.5 17.3 1.4 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF1664 PF07889.12 OQR89795.1 - 8.4 6.5 13.3 1.3 9.1 2.6 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) CBAH PF02275.18 OQR89797.1 - 2.4e-22 80.0 0.0 5.9e-22 78.7 0.0 1.7 1 1 0 1 1 1 1 Linear amide C-N hydrolases, choloylglycine hydrolase family Dirigent PF03018.14 OQR89797.1 - 0.088 12.6 0.0 0.15 11.9 0.0 1.3 1 0 0 1 1 1 0 Dirigent-like protein RasGAP PF00616.19 OQR89803.1 - 1e-24 87.4 0.7 1.2e-18 67.6 0.0 2.9 2 1 1 3 3 3 2 GTPase-activator protein for Ras-like GTPase PH PF00169.29 OQR89803.1 - 6.9e-11 42.6 0.0 1.4e-10 41.6 0.0 1.5 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 OQR89803.1 - 0.018 15.5 0.0 0.063 13.7 0.0 2.0 1 0 0 1 1 1 0 Pleckstrin homology domain Osteoregulin PF07175.11 OQR89803.1 - 0.059 13.6 1.3 0.14 12.3 1.3 1.6 1 0 0 1 1 1 0 Osteoregulin Glucan_synthase PF02364.15 OQR89804.1 - 6.5e-199 663.0 26.4 2.6e-175 584.9 22.4 3.4 1 1 1 2 2 2 2 1,3-beta-glucan synthase component HSP70 PF00012.20 OQR89805.1 - 4.7e-20 71.3 0.1 5.2e-20 71.2 0.1 1.0 1 0 0 1 1 1 1 Hsp70 protein Hydantoinase_A PF01968.18 OQR89805.1 - 0.09 12.0 0.0 0.099 11.9 0.0 1.0 1 0 0 1 1 1 0 Hydantoinase/oxoprolinase DUF2396 PF09654.10 OQR89806.1 - 0.0027 17.8 1.0 0.0067 16.5 1.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2396) Tox-REase-7 PF15649.6 OQR89806.1 - 0.038 14.3 0.0 0.23 11.8 0.0 2.3 2 1 0 2 2 2 0 Restriction endonuclease fold toxin 7 tRNA-synt_1g PF09334.11 OQR89806.1 - 0.1 11.3 5.2 0.18 10.5 4.8 1.6 1 1 1 2 2 2 0 tRNA synthetases class I (M) DUF2802 PF10975.8 OQR89806.1 - 0.66 10.1 0.1 0.66 10.1 0.1 3.0 3 1 1 4 4 4 0 Protein of unknown function (DUF2802) DUF3813 PF12758.7 OQR89806.1 - 9.2 6.7 10.6 2.3 8.6 3.4 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF3813) G-alpha PF00503.20 OQR89808.1 - 1.2e-102 343.7 6.7 2.2e-102 342.9 6.7 1.3 1 0 0 1 1 1 1 G-protein alpha subunit cNMP_binding PF00027.29 OQR89808.1 - 2.4e-28 98.1 0.1 1.2e-10 41.3 0.1 3.9 3 0 0 3 3 3 3 Cyclic nucleotide-binding domain Ion_trans PF00520.31 OQR89808.1 - 5.5e-22 78.2 89.1 7.7e-08 31.9 17.9 4.4 4 0 0 4 4 4 4 Ion transport protein Ion_trans_2 PF07885.16 OQR89808.1 - 3.8e-14 52.4 36.3 5.2e-06 26.3 3.9 5.2 4 0 0 4 4 4 4 Ion channel Arf PF00025.21 OQR89808.1 - 4.4e-12 45.8 0.7 5.7e-09 35.7 0.2 2.5 2 0 0 2 2 2 2 ADP-ribosylation factor family AAA_29 PF13555.6 OQR89808.1 - 0.12 12.1 0.0 0.55 10.0 0.0 2.1 2 0 0 2 2 2 0 P-loop containing region of AAA domain Roc PF08477.13 OQR89808.1 - 0.48 10.7 3.3 19 5.5 0.1 3.1 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase Gtr1_RagA PF04670.12 OQR89808.1 - 1.7 7.9 4.6 4.2 6.7 0.5 2.4 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region PH PF00169.29 OQR89809.1 - 3.6e-11 43.5 0.1 7.9e-11 42.4 0.1 1.6 1 0 0 1 1 1 1 PH domain PH_3 PF14593.6 OQR89809.1 - 9.6e-06 25.7 0.0 2.4e-05 24.4 0.0 1.7 1 0 0 1 1 1 1 PH domain PH_8 PF15409.6 OQR89809.1 - 0.00024 21.3 0.0 0.00061 20.0 0.0 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain PH_11 PF15413.6 OQR89809.1 - 0.015 15.7 0.4 0.23 11.9 0.4 2.5 1 1 0 1 1 1 0 Pleckstrin homology domain Ricin_B_lectin PF00652.22 OQR89812.1 - 3.1e-09 37.2 1.2 0.00017 21.8 0.7 3.1 2 1 1 3 3 3 3 Ricin-type beta-trefoil lectin domain N_Asn_amidohyd PF14736.6 OQR89813.1 - 5.6e-28 97.9 0.0 7e-28 97.5 0.0 1.1 1 0 0 1 1 1 1 Protein N-terminal asparagine amidohydrolase TPR_14 PF13428.6 OQR89818.1 - 4.2e-06 27.1 1.0 2.3e-05 24.8 0.2 2.7 2 1 1 3 3 3 2 Tetratricopeptide repeat Suf PF05843.14 OQR89818.1 - 2e-05 24.8 0.1 6.2e-05 23.1 0.0 1.7 2 0 0 2 2 2 1 Suppressor of forked protein (Suf) TPR_15 PF13429.6 OQR89818.1 - 0.00069 18.9 0.6 0.0013 18.0 0.6 1.3 1 0 0 1 1 1 1 Tetratricopeptide repeat NRDE-2 PF08424.10 OQR89818.1 - 0.00079 18.6 1.0 0.00079 18.6 1.0 1.6 2 0 0 2 2 2 1 NRDE-2, necessary for RNA interference TPR_19 PF14559.6 OQR89818.1 - 0.0029 18.1 0.1 0.2 12.2 0.0 2.5 1 1 1 2 2 2 2 Tetratricopeptide repeat Mad3_BUB1_I PF08311.12 OQR89818.1 - 0.041 13.9 0.3 0.43 10.6 0.1 2.2 1 1 0 2 2 2 0 Mad3/BUB1 homology region 1 Pkinase PF00069.25 OQR89820.1 - 2e-13 50.3 2.4 1.7e-12 47.3 0.0 3.1 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQR89820.1 - 4.3e-05 22.9 0.0 0.0001 21.7 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Ricin_B_lectin PF00652.22 OQR89821.1 - 4.5e-23 81.9 12.4 1.6e-12 47.8 2.2 2.3 2 0 0 2 2 2 2 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.6 OQR89821.1 - 1.6e-06 28.7 8.7 0.072 13.8 0.4 3.5 2 1 1 3 3 3 3 Ricin-type beta-trefoil lectin domain-like CDtoxinA PF03498.14 OQR89821.1 - 0.00035 20.2 9.5 0.061 12.9 0.1 3.2 2 1 1 3 3 3 2 Cytolethal distending toxin A/C domain Med13_C PF06333.12 OQR89821.1 - 0.67 9.2 8.2 0.9 8.8 8.2 1.3 1 0 0 1 1 1 0 Mediator complex subunit 13 C-terminal domain PH PF00169.29 OQR89822.1 - 5.7e-14 52.5 0.5 1.8e-08 34.8 0.0 2.9 2 1 0 2 2 2 2 PH domain PH_9 PF15410.6 OQR89822.1 - 0.075 13.4 1.9 2.1 8.7 0.0 3.0 3 1 0 3 3 3 0 Pleckstrin homology domain SUI1 PF01253.22 OQR89825.1 - 9.8e-21 74.1 0.0 2.9e-20 72.6 0.0 1.8 1 0 0 1 1 1 1 Translation initiation factor SUI1 DUF4611 PF15387.6 OQR89825.1 - 0.21 11.8 5.4 0.83 9.9 5.3 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4611) RXT2_N PF08595.11 OQR89825.1 - 0.22 11.5 1.3 0.43 10.6 1.3 1.4 1 0 0 1 1 1 0 RXT2-like, N-terminal Snf7 PF03357.21 OQR89825.1 - 4.2 6.9 6.4 0.86 9.2 0.5 2.4 2 1 0 2 2 2 0 Snf7 DNA_pol_phi PF04931.13 OQR89825.1 - 9.3 4.2 6.7 2.5 6.1 3.7 1.5 2 0 0 2 2 2 0 DNA polymerase phi Beach PF02138.18 OQR89826.1 - 1.3e-72 244.5 0.0 2.3e-72 243.7 0.0 1.4 1 0 0 1 1 1 1 Beige/BEACH domain IF-2B PF01008.17 OQR89827.1 - 2.4e-67 227.1 0.2 3.4e-67 226.6 0.2 1.1 1 0 0 1 1 1 1 Initiation factor 2 subunit family DUF2723 PF11028.8 OQR89828.1 - 1.4e-12 47.8 12.7 1.7e-12 47.6 10.4 2.3 3 0 0 3 3 3 1 Protein of unknown function (DUF2723) DUF2154 PF09922.9 OQR89832.1 - 0.00025 20.9 0.0 0.00039 20.3 0.0 1.3 1 0 0 1 1 1 1 Cell wall-active antibiotics response 4TMS YvqF AAA_18 PF13238.6 OQR89833.1 - 0.15 12.6 0.0 0.29 11.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain PLAC8 PF04749.17 OQR89835.1 - 2.3e-20 73.4 10.5 2.9e-20 73.1 10.5 1.1 1 0 0 1 1 1 1 PLAC8 family Ala_racemase_N PF01168.20 OQR89836.1 - 4.5e-25 88.6 0.0 5.7e-25 88.3 0.0 1.0 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain PIP5K PF01504.18 OQR89837.1 - 3.6e-64 216.6 0.0 5.1e-64 216.1 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase FGFR3_TM PF18123.1 OQR89837.1 - 0.048 13.2 2.7 0.33 10.5 2.7 2.6 1 0 0 1 1 1 0 Fibroblast growth factor receptor 3 transmembrane domain ParD_like PF11903.8 OQR89837.1 - 0.14 12.3 0.2 0.49 10.5 0.0 2.0 2 0 0 2 2 2 0 ParD-like antitoxin of type II bacterial toxin-antitoxin system 7tm_1 PF00001.21 OQR89837.1 - 0.71 9.2 7.8 1.3 8.2 7.3 1.8 1 1 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) LRR_8 PF13855.6 OQR89838.1 - 1.5e-37 127.1 69.3 1e-09 38.0 4.4 5.2 2 1 5 7 7 7 7 Leucine rich repeat LRR_4 PF12799.7 OQR89838.1 - 1.6e-22 79.2 37.6 1.5e-06 28.4 1.1 5.9 3 1 2 6 6 6 6 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 OQR89838.1 - 3.9e-06 26.7 33.3 0.7 10.7 1.2 8.9 8 1 1 9 9 9 2 Leucine Rich Repeat LRR_9 PF14580.6 OQR89838.1 - 3.2e-05 23.5 11.2 0.049 13.1 2.9 3.4 1 1 3 4 4 4 3 Leucine-rich repeat LRR_3 PF07725.12 OQR89838.1 - 0.055 13.3 0.4 0.055 13.3 0.4 2.9 2 0 0 2 2 2 0 Leucine Rich Repeat DUF2322 PF10084.9 OQR89838.1 - 0.11 12.6 0.7 49 4.1 0.0 3.3 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2322) SHOCT PF09851.9 OQR89838.1 - 0.13 12.0 0.2 0.53 10.1 0.2 2.1 1 0 0 1 1 1 0 Short C-terminal domain LRR_6 PF13516.6 OQR89838.1 - 0.79 9.9 24.1 0.61 10.3 0.3 7.0 8 0 0 8 8 8 0 Leucine Rich repeat LRR_4 PF12799.7 OQR89839.1 - 0.0044 17.4 30.9 0.048 14.1 0.8 7.6 3 2 5 8 8 8 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 OQR89839.1 - 8.8 6.2 20.6 2.4 8.0 2.5 5.8 4 2 2 6 6 6 0 Leucine rich repeat CCDC53 PF10152.9 OQR89841.1 - 4.1e-82 274.1 48.9 7.7e-12 45.9 2.9 9.6 7 2 2 9 9 8 8 Subunit CCDC53 of WASH complex FH2 PF02181.23 OQR89841.1 - 2.4e-75 254.0 0.4 3.5e-75 253.5 0.4 1.2 1 0 0 1 1 1 1 Formin Homology 2 Domain zf-HC5HC2H_2 PF13832.6 OQR89841.1 - 0.00017 21.7 1.7 0.00041 20.5 1.7 1.6 1 0 0 1 1 1 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 OQR89841.1 - 0.0019 18.4 1.7 0.0047 17.1 1.7 1.6 1 0 0 1 1 1 1 PHD-like zinc-binding domain DUF1664 PF07889.12 OQR89841.1 - 0.013 15.5 0.6 0.013 15.5 0.6 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) PHD PF00628.29 OQR89841.1 - 0.029 14.2 11.6 0.075 12.9 11.6 1.7 1 1 0 1 1 1 0 PHD-finger Fib_alpha PF08702.10 OQR89841.1 - 0.058 13.6 1.4 0.22 11.7 1.4 2.0 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Fez1 PF06818.15 OQR89841.1 - 0.06 13.8 3.0 0.16 12.4 3.0 1.6 1 0 0 1 1 1 0 Fez1 PSII_Pbs27 PF13326.6 OQR89841.1 - 0.08 13.3 0.2 0.3 11.4 0.2 2.0 1 0 0 1 1 1 0 Photosystem II Pbs27 ERCC3_RAD25_C PF16203.5 OQR89841.1 - 0.16 11.2 0.0 0.28 10.4 0.0 1.3 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase COG2 PF06148.11 OQR89841.1 - 0.47 10.5 1.9 2.2 8.4 0.4 2.4 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Baculo_PEP_C PF04513.12 OQR89841.1 - 3.7 7.6 6.1 1.2 9.2 2.4 2.0 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Ndc1_Nup PF09531.10 OQR89841.1 - 8.4 4.9 12.3 15 4.1 12.3 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup PH PF00169.29 OQR89842.1 - 1.4e-12 48.1 0.1 4.1e-08 33.7 0.1 2.5 2 0 0 2 2 2 2 PH domain PH_9 PF15410.6 OQR89842.1 - 0.017 15.5 0.2 18 5.8 0.0 3.2 3 0 0 3 3 3 0 Pleckstrin homology domain RXT2_N PF08595.11 OQR89842.1 - 0.026 14.6 5.2 0.21 11.6 1.7 2.3 2 0 0 2 2 2 0 RXT2-like, N-terminal GCIP PF13324.6 OQR89842.1 - 0.077 12.6 8.1 0.17 11.5 0.9 2.7 3 0 0 3 3 3 0 Grap2 and cyclin-D-interacting PH_11 PF15413.6 OQR89842.1 - 0.097 13.1 0.8 3.5 8.1 0.3 3.2 2 1 0 2 2 2 0 Pleckstrin homology domain ANAPC15 PF15243.6 OQR89842.1 - 0.19 12.2 13.4 0.066 13.6 4.3 2.6 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 15 Sigma70_ner PF04546.13 OQR89842.1 - 0.5 10.2 6.4 0.36 10.7 0.2 2.5 2 0 0 2 2 2 0 Sigma-70, non-essential region SDA1 PF05285.12 OQR89842.1 - 0.71 9.2 6.0 0.76 9.1 0.2 2.1 2 0 0 2 2 2 0 SDA1 FAM176 PF14851.6 OQR89842.1 - 0.83 9.3 7.0 1 9.0 0.7 2.4 2 0 0 2 2 2 0 FAM176 family PTPRCAP PF15713.5 OQR89842.1 - 0.88 9.9 11.9 0.079 13.2 2.1 2.3 2 0 0 2 2 2 0 Protein tyrosine phosphatase receptor type C-associated Cwf_Cwc_15 PF04889.12 OQR89842.1 - 1.2 8.8 15.6 0.17 11.6 5.6 2.3 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein PPP4R2 PF09184.11 OQR89842.1 - 2 7.9 8.0 10 5.6 2.5 2.2 2 0 0 2 2 2 0 PPP4R2 CobT PF06213.12 OQR89842.1 - 3.4 7.0 6.4 2.8 7.3 0.4 2.3 2 0 0 2 2 2 0 Cobalamin biosynthesis protein CobT PBP1_TM PF14812.6 OQR89842.1 - 8.8 6.8 21.7 2.4 8.6 1.2 2.5 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Pkinase PF00069.25 OQR89851.1 - 5.6e-138 458.6 0.0 6.2e-68 229.0 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OQR89851.1 - 2.9e-65 220.1 0.0 3e-32 111.9 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase PH PF00169.29 OQR89851.1 - 2e-23 82.9 0.3 1.4e-10 41.6 0.0 2.8 2 0 0 2 2 2 2 PH domain Haspin_kinase PF12330.8 OQR89851.1 - 4.3e-08 32.5 2.7 0.0032 16.4 0.1 2.6 3 0 0 3 3 3 2 Haspin like kinase domain PH_11 PF15413.6 OQR89851.1 - 5.4e-07 30.0 9.2 0.017 15.6 1.9 4.8 2 2 0 2 2 2 2 Pleckstrin homology domain SnoaL_2 PF12680.7 OQR89851.1 - 1.7e-06 28.6 0.9 0.045 14.4 0.1 2.6 2 0 0 2 2 2 2 SnoaL-like domain Kdo PF06293.14 OQR89851.1 - 1.4e-05 24.6 3.2 0.081 12.3 0.2 2.5 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OQR89851.1 - 0.0014 18.6 0.4 2.3 8.1 0.1 2.6 2 0 0 2 2 2 2 Phosphotransferase enzyme family PH_15 PF17339.2 OQR89851.1 - 0.0064 16.4 0.2 1.3 8.9 0.0 2.4 2 0 0 2 2 2 1 PH domain FTA2 PF13095.6 OQR89851.1 - 0.037 13.6 0.9 8.8 5.9 0.1 2.5 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Pox_ser-thr_kin PF05445.11 OQR89851.1 - 0.062 12.3 3.0 3.2 6.6 0.3 2.2 2 0 0 2 2 2 0 Poxvirus serine/threonine protein kinase R2K_3 PF14243.6 OQR89851.1 - 0.097 12.7 0.1 19 5.2 0.0 2.4 2 0 0 2 2 2 0 ATP-grasp domain, R2K clade family 3 PH_16 PF17838.1 OQR89851.1 - 0.16 11.8 0.1 13 5.7 0.0 2.4 2 0 0 2 2 2 0 PH domain DUF321 PF03778.13 OQR89851.1 - 0.49 10.1 2.1 26 4.6 0.2 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF321) ABC_tran PF00005.27 OQR89852.1 - 5.5e-06 26.9 0.2 1.7e-05 25.3 0.0 1.9 2 1 0 2 2 2 1 ABC transporter F-box-like PF12937.7 OQR89852.1 - 0.0038 17.1 0.1 0.0092 15.9 0.1 1.7 1 0 0 1 1 1 1 F-box-like SMC_N PF02463.19 OQR89852.1 - 0.053 13.0 0.3 0.097 12.1 0.1 1.5 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain F-box PF00646.33 OQR89852.1 - 0.055 13.4 0.0 0.15 12.0 0.0 1.7 1 0 0 1 1 1 0 F-box domain BRX_assoc PF16627.5 OQR89854.1 - 0.16 12.1 0.4 36 4.6 0.0 2.9 2 1 0 2 2 2 0 Unstructured region between BRX_N and BRX domain ATP-grasp_2 PF08442.10 OQR89856.1 - 7.9e-65 218.2 0.5 4.8e-64 215.6 0.0 2.0 2 0 0 2 2 2 1 ATP-grasp domain Ligase_CoA PF00549.19 OQR89856.1 - 8.1e-24 84.2 1.5 1.3e-23 83.5 1.5 1.3 1 0 0 1 1 1 1 CoA-ligase ATP-grasp_5 PF13549.6 OQR89856.1 - 3.3e-08 33.3 0.3 1e-07 31.7 0.1 1.9 2 1 0 2 2 2 1 ATP-grasp domain Peripla_BP_4 PF13407.6 OQR89856.1 - 0.0047 16.5 1.2 0.013 15.1 1.4 1.7 2 0 0 2 2 2 1 Periplasmic binding protein domain Toprim_2 PF13155.6 OQR89856.1 - 0.065 13.7 0.2 0.65 10.5 0.1 2.4 2 0 0 2 2 2 0 Toprim-like GARS_A PF01071.19 OQR89856.1 - 0.079 12.7 3.5 5.5 6.7 0.3 2.8 2 1 0 2 2 2 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain Pkinase PF00069.25 OQR89857.1 - 1.1e-32 113.5 0.1 1.3e-32 113.3 0.1 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQR89857.1 - 5.2e-26 91.5 0.0 6.1e-26 91.3 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 OQR89857.1 - 0.0014 18.1 0.0 0.0021 17.5 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 OQR89857.1 - 0.02 14.2 0.0 0.039 13.2 0.0 1.4 1 1 0 1 1 1 0 Kinase-like Haspin_kinase PF12330.8 OQR89857.1 - 0.036 13.0 0.0 0.045 12.7 0.0 1.1 1 0 0 1 1 1 0 Haspin like kinase domain APH PF01636.23 OQR89857.1 - 0.11 12.4 0.0 0.2 11.5 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Beach PF02138.18 OQR89857.1 - 0.11 11.8 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 Beige/BEACH domain ABC_membrane PF00664.23 OQR89860.1 - 1.5e-19 70.7 11.2 3.2e-19 69.6 11.2 1.6 1 0 0 1 1 1 1 ABC transporter transmembrane region PIG-X PF08320.12 OQR89865.1 - 7.8e-22 78.2 0.0 1.5e-21 77.3 0.0 1.4 1 0 0 1 1 1 1 PIG-X / PBN1 DUF5643 PF18705.1 OQR89865.1 - 0.011 15.7 0.7 0.052 13.5 0.3 2.2 2 1 0 2 2 2 0 Family of unknown function (DUF5643) MarR PF01047.22 OQR89865.1 - 0.075 13.0 0.0 0.34 10.9 0.0 2.1 2 0 0 2 2 2 0 MarR family adh_short PF00106.25 OQR89867.1 - 5.3e-45 153.3 5.1 7.2e-45 152.9 5.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OQR89867.1 - 1.5e-38 132.7 3.4 4.3e-38 131.2 3.4 1.7 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OQR89867.1 - 5.3e-17 62.3 1.3 7.2e-17 61.9 1.3 1.2 1 0 0 1 1 1 1 KR domain THF_DHG_CYH_C PF02882.19 OQR89867.1 - 0.0053 16.1 2.0 0.011 15.0 0.7 2.1 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Epimerase PF01370.21 OQR89867.1 - 0.0094 15.4 0.6 0.021 14.3 0.6 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.18 OQR89867.1 - 0.14 12.0 0.7 0.28 11.0 0.7 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF5353 PF17304.2 OQR89868.1 - 0.033 13.9 0.2 0.096 12.4 0.2 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5353) PspB PF06667.12 OQR89868.1 - 1.7 8.8 5.9 39 4.4 1.9 3.4 3 0 0 3 3 3 0 Phage shock protein B PrmA PF06325.13 OQR89880.1 - 6.4e-11 42.2 0.5 1.3e-10 41.1 0.5 1.5 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.6 OQR89880.1 - 2.3e-10 41.0 0.4 6.8e-10 39.5 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 OQR89880.1 - 1.3e-07 31.5 0.0 2.9e-07 30.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OQR89880.1 - 2.8e-07 31.1 0.0 8.8e-07 29.5 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OQR89880.1 - 6.8e-07 29.3 0.0 1.4e-06 28.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 OQR89880.1 - 1.9e-06 27.4 0.1 3.6e-06 26.5 0.1 1.4 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_9 PF08003.11 OQR89880.1 - 1.5e-05 24.1 0.0 2.1e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) MTS PF05175.14 OQR89880.1 - 6e-05 22.6 0.2 0.00011 21.8 0.2 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_18 PF12847.7 OQR89880.1 - 0.00019 21.4 0.4 0.00043 20.3 0.4 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OQR89880.1 - 0.00091 19.9 0.0 0.0021 18.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain TehB PF03848.14 OQR89880.1 - 0.0045 16.4 0.1 0.04 13.3 0.1 2.2 2 0 0 2 2 2 1 Tellurite resistance protein TehB zf-C2H2_2 PF12756.7 OQR89880.1 - 0.0098 16.2 0.6 0.026 14.9 0.6 1.7 1 0 0 1 1 1 1 C2H2 type zinc-finger (2 copies) FtsJ PF01728.19 OQR89880.1 - 0.0099 16.0 0.0 0.023 14.8 0.0 1.6 1 0 0 1 1 1 1 FtsJ-like methyltransferase PCMT PF01135.19 OQR89880.1 - 0.015 15.0 0.1 0.024 14.4 0.1 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Ubie_methyltran PF01209.18 OQR89880.1 - 0.024 14.0 0.1 0.039 13.3 0.1 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_32 PF13679.6 OQR89880.1 - 0.061 13.3 1.2 0.11 12.5 0.1 1.9 2 0 0 2 2 2 0 Methyltransferase domain Wtap PF17098.5 OQR89880.1 - 0.073 13.0 1.1 0.11 12.4 1.1 1.2 1 0 0 1 1 1 0 WTAP/Mum2p family AATF-Che1 PF13339.6 OQR89880.1 - 0.13 13.0 0.2 0.3 11.8 0.2 1.6 1 0 0 1 1 1 0 Apoptosis antagonizing transcription factor Spc24 PF08286.11 OQR89880.1 - 0.13 12.5 1.6 0.28 11.5 1.6 1.4 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 Cons_hypoth95 PF03602.15 OQR89880.1 - 0.15 11.7 0.0 0.37 10.4 0.0 1.7 1 0 0 1 1 1 0 Conserved hypothetical protein 95 zf-CpG_bind_C PF12269.8 OQR89880.1 - 1.5 8.5 4.9 13 5.4 0.5 2.1 2 0 0 2 2 2 0 CpG binding protein zinc finger C terminal domain HECT PF00632.25 OQR89885.1 - 4.4e-74 249.7 0.0 6.2e-74 249.2 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) zf-RanBP PF00641.18 OQR89885.1 - 7.8e-06 25.1 3.3 1.4e-05 24.3 3.3 1.4 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others DUF2070 PF09843.9 OQR89887.1 - 0.42 8.8 3.2 0.49 8.6 3.2 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Claudin_2 PF13903.6 OQR89887.1 - 6.9 6.4 11.6 3.9e+02 0.7 11.1 2.9 1 1 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction ABC2_membrane PF01061.24 OQR89888.1 - 4.1e-66 222.4 83.1 1.2e-35 122.8 33.9 2.8 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.27 OQR89888.1 - 3.7e-33 114.9 0.2 3.3e-17 63.3 0.1 2.5 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 OQR89888.1 - 7.1e-06 26.0 0.3 0.13 12.1 0.0 3.2 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 OQR89888.1 - 1.7e-05 24.8 0.2 0.0039 17.1 0.0 2.5 2 0 0 2 2 2 1 RsgA GTPase AAA_16 PF13191.6 OQR89888.1 - 1.8e-05 25.2 0.4 0.062 13.7 0.1 2.4 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.6 OQR89888.1 - 6e-05 22.7 3.7 0.023 14.4 0.2 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain ABC2_membrane_3 PF12698.7 OQR89888.1 - 0.00011 21.5 21.9 0.00011 21.5 21.9 3.8 2 2 0 3 3 3 2 ABC-2 family transporter protein MMR_HSR1 PF01926.23 OQR89888.1 - 0.0014 18.7 1.5 0.5 10.5 0.1 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_22 PF13401.6 OQR89888.1 - 0.0028 18.0 0.2 0.4 10.9 0.1 2.6 2 0 0 2 2 2 1 AAA domain PolyG_pol PF01518.16 OQR89888.1 - 0.0073 15.0 0.0 0.014 14.2 0.0 1.3 1 0 0 1 1 1 1 Sigma NS protein PDR_CDR PF06422.12 OQR89888.1 - 0.011 15.6 12.8 0.071 13.0 0.5 3.6 3 0 0 3 3 3 0 CDR ABC transporter AAA_25 PF13481.6 OQR89888.1 - 0.013 15.1 0.5 0.45 10.1 0.1 2.4 2 0 0 2 2 2 0 AAA domain SMC_N PF02463.19 OQR89888.1 - 0.024 14.1 1.2 0.65 9.4 0.1 2.8 2 2 0 2 2 2 0 RecF/RecN/SMC N terminal domain DUF4227 PF14004.6 OQR89888.1 - 0.025 14.5 0.0 0.16 12.0 0.0 2.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4227) AAA_28 PF13521.6 OQR89888.1 - 0.026 14.8 0.3 2.1 8.6 0.2 2.6 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 OQR89888.1 - 0.038 13.2 0.1 7.7 5.7 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin Dynamin_N PF00350.23 OQR89888.1 - 0.046 13.8 0.9 1.8 8.6 0.3 2.4 2 0 0 2 2 2 0 Dynamin family AAA_30 PF13604.6 OQR89888.1 - 0.05 13.3 0.7 0.28 10.9 0.2 2.1 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 OQR89888.1 - 0.054 14.1 0.0 5 7.7 0.0 2.5 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 OQR89888.1 - 0.16 11.9 0.9 19 5.1 0.0 3.3 3 0 0 3 3 3 0 NTPase Roc PF08477.13 OQR89888.1 - 0.21 11.8 0.5 38 4.5 0.0 2.8 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_23 PF13476.6 OQR89888.1 - 0.43 11.1 0.9 3.2 8.2 0.4 2.3 2 0 0 2 2 2 0 AAA domain ABC2_membrane PF01061.24 OQR89889.1 - 2.4e-135 448.6 173.6 1.6e-37 129.0 31.3 5.9 7 0 0 7 7 7 4 ABC-2 type transporter ABC_tran PF00005.27 OQR89889.1 - 7.3e-65 217.6 2.0 2.5e-17 63.7 0.1 4.9 5 0 0 5 5 5 4 ABC transporter AAA_16 PF13191.6 OQR89889.1 - 5.7e-12 46.3 1.9 0.21 11.9 0.1 4.4 4 0 0 4 4 4 4 AAA ATPase domain RsgA_GTPase PF03193.16 OQR89889.1 - 5.8e-12 45.8 4.0 0.0015 18.5 0.0 4.9 5 0 0 5 5 5 2 RsgA GTPase AAA_21 PF13304.6 OQR89889.1 - 6.8e-12 45.8 5.3 0.4 10.4 0.0 6.3 6 0 0 6 6 6 3 AAA domain, putative AbiEii toxin, Type IV TA system ABC2_membrane_3 PF12698.7 OQR89889.1 - 4.6e-11 42.4 142.7 1.4e-05 24.4 23.4 6.3 4 3 2 6 6 4 4 ABC-2 family transporter protein SMC_N PF02463.19 OQR89889.1 - 6.2e-11 42.1 4.1 0.00051 19.5 0.0 5.4 5 1 0 6 6 6 2 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 OQR89889.1 - 6.1e-10 39.5 1.1 1.6 9.0 0.0 5.5 5 0 0 5 5 5 2 AAA domain AAA_29 PF13555.6 OQR89889.1 - 3.1e-09 36.5 16.9 0.024 14.4 0.4 5.0 5 0 0 5 5 5 4 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 OQR89889.1 - 3e-08 33.7 3.6 0.18 11.9 0.0 4.6 4 0 0 4 4 4 2 50S ribosome-binding GTPase PDR_CDR PF06422.12 OQR89889.1 - 5.1e-07 29.5 3.1 5.6e-06 26.2 0.5 6.5 8 0 0 8 8 4 2 CDR ABC transporter AAA_25 PF13481.6 OQR89889.1 - 8.1e-07 28.8 3.1 0.26 10.8 0.1 5.1 5 0 0 5 5 5 2 AAA domain AAA_23 PF13476.6 OQR89889.1 - 1.1e-05 26.0 3.1 0.55 10.7 0.1 4.0 4 0 0 4 4 4 2 AAA domain Zeta_toxin PF06414.12 OQR89889.1 - 0.00016 21.0 5.4 4.2 6.6 0.0 4.3 4 0 0 4 4 4 1 Zeta toxin AAA_28 PF13521.6 OQR89889.1 - 0.0003 21.1 6.0 13 6.0 1.0 4.8 4 0 0 4 4 4 0 AAA domain Gtr1_RagA PF04670.12 OQR89889.1 - 0.00041 19.8 2.7 3.9 6.8 0.0 4.7 5 0 0 5 5 5 1 Gtr1/RagA G protein conserved region AAA_18 PF13238.6 OQR89889.1 - 0.00042 20.9 0.7 14 6.2 0.0 4.7 5 0 0 5 5 4 0 AAA domain AAA_30 PF13604.6 OQR89889.1 - 0.00048 19.9 5.7 0.33 10.7 0.2 3.8 4 0 0 4 4 4 2 AAA domain Dynamin_N PF00350.23 OQR89889.1 - 0.0034 17.4 5.5 6.3 6.8 0.1 4.5 4 0 0 4 4 4 0 Dynamin family AAA PF00004.29 OQR89889.1 - 0.0046 17.4 6.1 17 5.8 0.2 5.1 4 2 0 4 4 4 0 ATPase family associated with various cellular activities (AAA) Roc PF08477.13 OQR89889.1 - 0.0054 16.9 4.9 12 6.1 0.0 4.6 4 0 0 4 4 4 0 Ras of Complex, Roc, domain of DAPkinase RNA_helicase PF00910.22 OQR89889.1 - 0.0065 16.8 4.0 20 5.6 0.0 4.6 4 0 0 4 4 4 0 RNA helicase AAA_33 PF13671.6 OQR89889.1 - 0.0071 16.5 1.6 13 5.9 0.0 4.0 4 0 0 4 4 4 0 AAA domain Ploopntkinase3 PF18751.1 OQR89889.1 - 0.044 13.7 5.3 5.3 6.9 0.0 4.0 4 0 0 4 4 4 0 P-loop Nucleotide Kinase3 SbcCD_C PF13558.6 OQR89889.1 - 0.095 12.9 0.0 21 5.5 0.0 3.0 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit FeoB_N PF02421.18 OQR89889.1 - 0.13 11.7 5.7 40 3.7 0.0 4.2 4 0 0 4 4 4 0 Ferrous iron transport protein B KTI12 PF08433.10 OQR89889.1 - 0.16 11.4 0.2 7.3 5.9 0.0 2.4 2 0 0 2 2 2 0 Chromatin associated protein KTI12 MCM PF00493.23 OQR89889.1 - 0.16 11.1 0.1 19 4.3 0.0 2.6 2 0 0 2 2 2 0 MCM P-loop domain TsaE PF02367.17 OQR89889.1 - 0.22 11.5 5.0 9.2 6.3 0.2 3.3 3 0 0 3 3 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE PduV-EutP PF10662.9 OQR89889.1 - 0.4 10.4 8.1 11 5.8 0.3 4.1 4 0 0 4 4 4 0 Ethanolamine utilisation - propanediol utilisation CbtB PF09489.10 OQR89889.1 - 0.4 10.8 5.6 19 5.5 0.7 4.0 2 0 0 2 2 2 0 Probable cobalt transporter subunit (CbtB) PRK PF00485.18 OQR89889.1 - 1.1 9.0 3.6 26 4.5 0.1 3.1 3 0 0 3 3 2 0 Phosphoribulokinase / Uridine kinase family TssO PF17561.2 OQR89889.1 - 1.2 9.2 9.1 0.16 12.1 0.2 3.6 3 0 0 3 3 2 0 Type VI secretion system, TssO AAA_24 PF13479.6 OQR89889.1 - 2.8 7.6 10.4 33 4.1 0.5 4.3 4 0 0 4 4 4 0 AAA domain DnaB_C PF03796.15 OQR89889.1 - 3.6 6.8 4.6 31 3.8 0.0 3.1 4 0 0 4 4 4 0 DnaB-like helicase C terminal domain FKBP_C PF00254.28 OQR89893.1 - 1.2e-35 121.7 0.0 1.4e-35 121.5 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase HTH_5 PF01022.20 OQR89894.1 - 0.048 13.5 0.0 0.11 12.4 0.0 1.6 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family Gifsy-2 PF13856.6 OQR89895.1 - 0.072 13.5 0.1 0.15 12.5 0.1 1.4 1 0 0 1 1 1 0 ATP-binding sugar transporter from pro-phage ALMT PF11744.8 OQR89895.1 - 3.1 6.5 6.4 2.1 7.1 5.1 1.3 1 1 0 1 1 1 0 Aluminium activated malate transporter DUF2115 PF09888.9 OQR89900.1 - 0.55 10.7 4.3 0.38 11.3 2.1 1.8 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2115) REJ PF02010.15 OQR89904.1 - 4.9e-53 180.5 16.1 5.5e-52 177.1 11.3 3.8 4 1 1 5 5 5 2 REJ domain GPS PF01825.21 OQR89904.1 - 1e-11 45.2 1.6 4.5e-11 43.1 1.6 2.2 1 0 0 1 1 1 1 GPCR proteolysis site, GPS, motif EGF_2 PF07974.13 OQR89904.1 - 0.51 10.8 8.1 1.4 9.3 8.1 1.7 1 0 0 1 1 1 0 EGF-like domain Pkinase PF00069.25 OQR89905.1 - 6.7e-24 84.7 0.0 7.8e-24 84.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQR89905.1 - 1.4e-20 73.7 0.0 1.9e-20 73.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase HlyE PF06109.13 OQR89906.1 - 8.4e-07 28.6 0.4 1.3e-06 28.0 0.4 1.3 1 0 0 1 1 1 1 Haemolysin E (HlyE) Ald_deCOase PF11266.8 OQR89906.1 - 0.018 14.7 0.2 0.042 13.6 0.2 1.6 1 0 0 1 1 1 0 Long-chain fatty aldehyde decarbonylase Myosin_head PF00063.21 OQR89908.1 - 1.7e-215 717.3 0.5 2.3e-194 647.4 0.3 2.1 2 0 0 2 2 2 2 Myosin head (motor domain) IQ PF00612.27 OQR89908.1 - 1.2e-12 46.4 34.3 0.0016 18.1 1.0 5.7 5 0 0 5 5 5 5 IQ calmodulin-binding motif PDZ_6 PF17820.1 OQR89908.1 - 1.7e-07 31.0 0.1 0.078 12.8 0.0 3.7 3 0 0 3 3 3 2 PDZ domain PDZ PF00595.24 OQR89908.1 - 7.4e-06 26.2 0.0 0.035 14.5 0.0 3.8 3 1 0 3 3 3 1 PDZ domain Tricorn_PDZ PF14685.6 OQR89908.1 - 0.002 18.0 0.0 0.21 11.6 0.0 3.2 3 0 0 3 3 3 1 Tricorn protease PDZ domain PDZ_2 PF13180.6 OQR89908.1 - 0.014 15.7 0.1 5.7 7.3 0.0 3.5 4 0 0 4 4 4 0 PDZ domain AAA_22 PF13401.6 OQR89908.1 - 0.04 14.2 0.0 0.24 11.7 0.0 2.3 2 0 0 2 2 2 0 AAA domain T2SSE PF00437.20 OQR89908.1 - 0.058 12.4 0.0 0.11 11.5 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_16 PF13191.6 OQR89908.1 - 0.058 13.8 0.7 0.21 12.0 0.0 2.3 3 0 0 3 3 2 0 AAA ATPase domain Hpr_kinase_C PF07475.12 OQR89908.1 - 0.072 12.6 0.1 5 6.6 0.0 2.3 2 0 0 2 2 2 0 HPr Serine kinase C-terminal domain Sigma54_activat PF00158.26 OQR89908.1 - 0.091 12.5 0.0 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_19 PF13245.6 OQR89908.1 - 0.12 12.7 0.0 0.52 10.6 0.0 2.1 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 OQR89908.1 - 0.18 12.3 0.9 0.42 11.1 0.1 2.1 2 0 0 2 2 2 0 ABC transporter DUF4207 PF13904.6 OQR89908.1 - 0.96 9.1 7.8 1.6 8.4 7.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4207) DDRGK PF09756.9 OQR89908.1 - 1.9 8.1 8.6 6.5 6.3 6.8 2.3 2 0 0 2 2 2 0 DDRGK domain Myosin_head PF00063.21 OQR89909.1 - 2.6e-216 720.0 0.0 3.4e-216 719.6 0.0 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) AAA_16 PF13191.6 OQR89909.1 - 0.0022 18.4 0.0 0.0055 17.1 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 OQR89909.1 - 0.075 13.3 0.0 0.38 11.0 0.0 2.2 2 0 0 2 2 2 0 AAA domain Hpr_kinase_C PF07475.12 OQR89909.1 - 0.15 11.6 0.0 6.7 6.2 0.0 2.3 2 0 0 2 2 2 0 HPr Serine kinase C-terminal domain DENN PF02141.21 OQR89910.1 - 1.7e-34 119.4 2.8 6.9e-33 114.2 2.8 2.5 1 1 0 1 1 1 1 DENN (AEX-3) domain dDENN PF03455.19 OQR89910.1 - 6.1e-06 26.1 0.0 1.5e-05 24.9 0.0 1.6 1 0 0 1 1 1 1 dDENN domain RGS PF00615.19 OQR89910.1 - 0.00072 19.8 5.6 0.4 11.0 3.6 2.5 2 0 0 2 2 2 2 Regulator of G protein signaling domain Phage_Integr_2 PF13009.6 OQR89910.1 - 1.3 8.0 4.0 7 5.7 1.0 2.1 1 1 1 2 2 2 0 Putative phage integrase DUF4205 PF13898.6 OQR89912.1 - 8.3e-99 330.8 0.0 1.3e-98 330.2 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4205) Myb_DNA-binding PF00249.31 OQR89912.1 - 0.0059 16.8 1.1 0.034 14.4 0.9 2.2 2 0 0 2 2 2 1 Myb-like DNA-binding domain WBS_methylT PF12589.8 OQR89912.1 - 8 7.3 10.4 11 6.8 8.4 2.3 1 1 0 1 1 1 0 Methyltransferase involved in Williams-Beuren syndrome Metallophos PF00149.28 OQR89913.1 - 1e-15 58.8 0.1 1.5e-15 58.2 0.1 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase RRM_1 PF00076.22 OQR89914.1 - 0.013 15.3 0.1 0.86 9.5 0.0 3.4 4 0 0 4 4 4 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Forkhead PF00250.18 OQR89914.1 - 0.058 13.7 0.1 0.17 12.1 0.1 1.8 1 0 0 1 1 1 0 Forkhead domain MIEAP PF16026.5 OQR89914.1 - 0.17 12.1 5.2 4.9 7.3 0.0 3.2 4 0 0 4 4 4 0 Mitochondria-eating protein Vma12 PF11712.8 OQR89914.1 - 0.36 10.9 9.2 6.5 6.8 0.1 3.0 3 0 0 3 3 3 0 Endoplasmic reticulum-based factor for assembly of V-ATPase Clat_adaptor_s PF01217.20 OQR89916.1 - 4.7e-44 149.8 3.4 5.2e-44 149.6 3.4 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain HOCHOB PF17943.1 OQR89916.1 - 0.025 15.3 1.7 0.67 10.7 0.8 2.8 2 1 0 2 2 2 0 Homeobox-cysteine loop-homeobox AAA_11 PF13086.6 OQR89917.1 - 6.1e-66 222.9 3.5 1.4e-33 116.8 0.0 2.7 3 0 0 3 3 3 2 AAA domain AAA_12 PF13087.6 OQR89917.1 - 6.2e-61 205.5 0.0 1.7e-60 204.1 0.0 1.8 2 0 0 2 2 2 1 AAA domain UCH PF00443.29 OQR89917.1 - 2.5e-14 53.4 0.0 5.5e-14 52.3 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase VPS13 PF16908.5 OQR89917.1 - 1.4e-13 51.2 2.5 2.1e-10 40.8 0.4 2.4 2 0 0 2 2 2 2 Vacuolar sorting-associated protein 13, N-terminal UCH_1 PF13423.6 OQR89917.1 - 7.9e-13 48.7 0.0 1.8e-12 47.5 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase AAA_30 PF13604.6 OQR89917.1 - 3.7e-11 43.1 0.1 6.5e-07 29.3 0.0 2.6 2 0 0 2 2 2 2 AAA domain Viral_helicase1 PF01443.18 OQR89917.1 - 1.3e-08 34.9 0.0 0.027 14.2 0.1 3.3 3 0 0 3 3 3 3 Viral (Superfamily 1) RNA helicase AAA_19 PF13245.6 OQR89917.1 - 9e-07 29.3 0.1 0.00087 19.6 0.0 2.5 2 0 0 2 2 2 2 AAA domain Chorein_N PF12624.7 OQR89917.1 - 1.7e-06 28.2 0.0 7.1e-06 26.1 0.0 2.1 1 0 0 1 1 1 1 N-terminal region of Chorein or VPS13 AAA_22 PF13401.6 OQR89917.1 - 4.6e-05 23.7 0.1 0.00093 19.5 0.0 2.9 3 0 0 3 3 2 1 AAA domain ResIII PF04851.15 OQR89917.1 - 0.00022 21.2 0.1 1.5 8.8 0.0 3.4 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit T2SSE PF00437.20 OQR89917.1 - 0.0039 16.3 0.6 0.0076 15.3 0.1 1.7 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA PF00004.29 OQR89917.1 - 0.0058 17.1 0.0 0.024 15.1 0.0 2.1 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 OQR89917.1 - 0.0087 16.5 0.5 0.035 14.5 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain DUF2075 PF09848.9 OQR89917.1 - 0.0088 15.3 0.3 4.1 6.5 0.0 3.2 3 0 0 3 3 3 1 Uncharacterized conserved protein (DUF2075) PhoH PF02562.16 OQR89917.1 - 0.039 13.4 0.2 2 7.8 0.1 2.4 2 0 0 2 2 2 0 PhoH-like protein AAA_7 PF12775.7 OQR89917.1 - 0.087 12.3 0.0 0.18 11.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region Rad17 PF03215.15 OQR89917.1 - 0.088 12.7 0.0 0.26 11.2 0.0 1.8 1 0 0 1 1 1 0 Rad17 P-loop domain ATPase_2 PF01637.18 OQR89917.1 - 0.14 12.0 0.0 4.2 7.2 0.0 2.4 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea AAA_18 PF13238.6 OQR89917.1 - 0.16 12.6 0.0 0.87 10.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain WD40 PF00400.32 OQR89918.1 - 2e-27 94.9 17.5 2e-06 28.4 0.3 6.5 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OQR89918.1 - 1.5e-16 60.5 4.7 4.8e-06 26.8 0.2 3.9 1 1 3 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 OQR89918.1 - 1.3e-06 28.4 0.0 0.083 12.8 0.1 3.1 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A DPPIV_N PF00930.21 OQR89918.1 - 0.1 11.3 0.0 4.4 6.0 0.0 2.4 2 0 0 2 2 2 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region DUF1674 PF07896.12 OQR89921.1 - 1e-09 38.7 3.2 2.3e-09 37.6 3.2 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF1674) Myotub-related PF06602.14 OQR89922.1 - 9.7e-109 363.5 0.0 1.4e-108 363.0 0.0 1.3 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain VPS13_C PF16909.5 OQR89922.1 - 0.00053 19.8 1.2 0.00096 19.0 1.2 1.4 1 0 0 1 1 1 1 Vacuolar-sorting-associated 13 protein C-terminal Y_phosphatase3 PF13350.6 OQR89922.1 - 0.036 14.0 0.0 0.065 13.2 0.0 1.5 1 0 0 1 1 1 0 Tyrosine phosphatase family GRAM PF02893.20 OQR89922.1 - 0.037 13.9 0.0 0.071 13.0 0.0 1.4 1 0 0 1 1 1 0 GRAM domain PH_TFIIH PF08567.11 OQR89922.1 - 0.04 14.2 0.0 0.085 13.2 0.0 1.5 1 0 0 1 1 1 0 TFIIH p62 subunit, N-terminal domain Vps36_ESCRT-II PF11605.8 OQR89922.1 - 0.083 13.1 0.0 0.18 12.0 0.0 1.5 1 0 0 1 1 1 0 Vacuolar protein sorting protein 36 Vps36 IQ PF00612.27 OQR89923.1 - 2e-10 39.5 49.0 0.0014 18.3 0.8 8.8 8 0 0 8 8 8 6 IQ calmodulin-binding motif LRR_4 PF12799.7 OQR89923.1 - 1.1e-05 25.7 7.9 0.094 13.2 0.1 4.6 3 1 3 6 6 6 3 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 OQR89923.1 - 1.8 8.9 16.7 1.7 8.9 0.1 5.6 7 0 0 7 7 7 0 Leucine Rich repeat LRR_1 PF00560.33 OQR89923.1 - 1.8 9.4 8.4 2.4e+02 3.0 0.0 6.1 7 0 0 7 7 7 0 Leucine Rich Repeat LRR_8 PF13855.6 OQR89926.1 - 1.1e-14 53.9 41.3 6.5e-08 32.2 5.1 3.8 1 1 3 4 4 4 4 Leucine rich repeat LRR_4 PF12799.7 OQR89926.1 - 1.9e-09 37.6 28.1 8e-05 22.9 3.8 4.5 1 1 4 5 5 5 5 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 OQR89926.1 - 1.2e-08 34.3 18.7 0.0027 17.6 0.2 5.9 6 0 0 6 6 6 4 Leucine Rich repeat LRR_9 PF14580.6 OQR89926.1 - 9e-05 22.0 4.9 0.0001 21.8 3.0 1.9 1 1 1 2 2 2 1 Leucine-rich repeat LRR_1 PF00560.33 OQR89926.1 - 0.00074 19.7 17.7 0.33 11.7 1.1 6.5 5 1 0 5 5 5 2 Leucine Rich Repeat Pkinase_Tyr PF07714.17 OQR89926.1 - 0.083 12.2 0.0 0.13 11.5 0.0 1.3 1 0 0 1 1 1 0 Protein tyrosine kinase Pkinase PF00069.25 OQR89926.1 - 0.12 11.7 0.0 0.22 10.8 0.0 1.4 1 0 0 1 1 1 0 Protein kinase domain DUF5437 PF17505.2 OQR89926.1 - 0.17 12.0 0.2 5.1 7.2 0.0 2.7 3 0 0 3 3 3 0 Family of unknown function (DUF5437) PheRS_DBD2 PF18554.1 OQR89926.1 - 0.35 10.9 1.1 10 6.2 0.1 2.6 2 0 0 2 2 2 0 PheRS DNA binding domain 2 Myosin_head PF00063.21 OQR89929.1 - 8.4e-215 715.0 1.8 1.6e-214 714.1 1.8 1.4 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_TH1 PF06017.13 OQR89929.1 - 5.5e-33 114.2 5.8 5.5e-33 114.2 5.8 1.9 2 0 0 2 2 2 1 Unconventional myosin tail, actin- and lipid-binding AAA_22 PF13401.6 OQR89929.1 - 0.00033 20.9 0.1 0.017 15.4 0.0 3.0 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.6 OQR89929.1 - 0.0031 17.9 0.1 0.0092 16.4 0.1 1.9 1 1 0 1 1 1 1 AAA ATPase domain AAA_19 PF13245.6 OQR89929.1 - 0.018 15.4 0.0 0.043 14.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 OQR89929.1 - 0.048 13.4 0.0 0.11 12.3 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain TMEM65 PF10507.9 OQR89930.1 - 1.4e-36 124.8 2.3 2.5e-36 123.9 2.3 1.4 1 0 0 1 1 1 1 Transmembrane protein 65 EF-hand_1 PF00036.32 OQR89930.1 - 0.05 13.2 0.0 0.13 11.9 0.0 1.7 1 0 0 1 1 1 0 EF hand EF-hand_7 PF13499.6 OQR89930.1 - 0.058 13.8 0.3 0.33 11.4 0.3 2.1 1 1 0 1 1 1 0 EF-hand domain pair EF-hand_6 PF13405.6 OQR89930.1 - 0.14 12.1 0.0 0.3 11.1 0.0 1.5 1 0 0 1 1 1 0 EF-hand domain HSF_DNA-bind PF00447.17 OQR89931.1 - 3.3e-25 88.5 1.0 3.3e-25 88.5 1.0 2.0 2 0 0 2 2 2 1 HSF-type DNA-binding NPM1-C PF16276.5 OQR89931.1 - 0.03 14.3 0.1 0.1 12.6 0.1 1.9 1 0 0 1 1 1 0 Nucleophosmin C-terminal domain ABC_membrane PF00664.23 OQR89941.1 - 1.4e-35 123.3 2.3 1.6e-35 123.1 2.3 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region CDC45 PF02724.14 OQR89944.1 - 0.022 13.1 22.5 0.027 12.8 22.5 1.2 1 0 0 1 1 1 0 CDC45-like protein NUDIX PF00293.28 OQR89945.1 - 2.9e-11 43.5 0.0 8.7e-11 42.0 0.0 1.7 2 0 0 2 2 2 1 NUDIX domain DUF5435 PF17503.2 OQR89946.1 - 0.028 14.2 0.1 0.031 14.0 0.1 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5435) WD40 PF00400.32 OQR89947.1 - 8e-17 61.3 5.8 0.00015 22.5 0.9 5.2 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OQR89947.1 - 8.5e-08 32.4 0.1 0.6 10.5 0.0 4.2 3 1 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Cytochrom_D1 PF02239.16 OQR89947.1 - 1.2e-05 24.1 0.2 0.03 12.8 0.1 2.3 2 0 0 2 2 2 2 Cytochrome D1 heme domain PQQ PF01011.21 OQR89947.1 - 0.021 14.8 0.0 0.06 13.3 0.0 1.7 1 0 0 1 1 1 0 PQQ enzyme repeat Exo_endo_phos PF03372.23 OQR89963.1 - 1e-05 25.2 0.0 5.8e-05 22.7 0.0 2.1 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family CybS PF05328.12 OQR89964.1 - 6.3e-13 48.6 0.0 8.6e-13 48.1 0.0 1.2 1 0 0 1 1 1 1 CybS, succinate dehydrogenase cytochrome B small subunit MaoC_dehydratas PF01575.19 OQR89965.1 - 8.4e-21 73.8 0.0 1.1e-20 73.4 0.0 1.1 1 0 0 1 1 1 1 MaoC like domain MaoC_dehydrat_N PF13452.6 OQR89965.1 - 4.1e-08 33.4 0.0 1.5e-07 31.6 0.0 1.7 1 1 0 1 1 1 1 N-terminal half of MaoC dehydratase Thioredoxin PF00085.20 OQR89966.1 - 6.8e-62 205.9 3.0 1.2e-29 102.3 0.0 3.6 4 1 0 4 4 4 2 Thioredoxin Thioredoxin_6 PF13848.6 OQR89966.1 - 4.3e-35 121.3 5.9 1.7e-25 90.0 0.3 3.4 2 1 1 3 3 3 3 Thioredoxin-like domain Thioredoxin_2 PF13098.6 OQR89966.1 - 1.9e-12 47.6 2.4 5.3e-05 23.6 0.1 4.5 3 2 0 3 3 3 2 Thioredoxin-like domain OST3_OST6 PF04756.13 OQR89966.1 - 7.9e-11 41.8 0.3 0.00042 19.8 0.0 2.7 3 0 0 3 3 3 2 OST3 / OST6 family, transporter family Thioredoxin_8 PF13905.6 OQR89966.1 - 1.7e-08 34.7 0.0 0.0048 17.2 0.0 4.2 2 1 1 3 3 3 2 Thioredoxin-like AhpC-TSA PF00578.21 OQR89966.1 - 1.8e-08 34.3 0.3 0.015 15.2 0.0 3.5 3 1 1 4 4 4 2 AhpC/TSA family Thioredoxin_7 PF13899.6 OQR89966.1 - 4.8e-08 33.1 0.0 0.018 15.2 0.0 3.1 2 1 0 2 2 2 2 Thioredoxin-like ERp29_N PF07912.13 OQR89966.1 - 0.00022 21.4 0.7 1.3 9.2 0.0 3.6 4 0 0 4 4 4 2 ERp29, N-terminal domain Redoxin PF08534.10 OQR89966.1 - 0.00023 20.9 2.7 0.69 9.6 0.0 3.9 4 1 0 4 4 4 2 Redoxin HyaE PF07449.11 OQR89966.1 - 0.0022 17.9 1.3 3.1 7.8 0.0 3.8 2 1 1 3 3 3 1 Hydrogenase-1 expression protein HyaE Thioredoxin_9 PF14595.6 OQR89966.1 - 0.03 14.1 0.0 4.1 7.2 0.0 2.6 2 0 0 2 2 2 0 Thioredoxin Helicase_C PF00271.31 OQR89966.1 - 0.068 13.5 0.1 0.47 10.8 0.1 2.4 2 0 0 2 2 2 0 Helicase conserved C-terminal domain COG5 PF10392.9 OQR89966.1 - 0.11 12.7 0.1 2.1 8.5 0.0 2.5 2 1 1 3 3 3 0 Golgi transport complex subunit 5 DUF4395 PF14340.6 OQR89967.1 - 0.0086 16.4 0.9 0.013 15.8 0.9 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4395) IspA PF04279.15 OQR89967.1 - 0.015 15.5 4.5 0.024 14.8 4.0 1.6 1 1 1 2 2 2 0 Intracellular septation protein A EamA PF00892.20 OQR89967.1 - 0.024 14.8 2.6 0.024 14.8 2.6 2.7 2 2 1 3 3 3 0 EamA-like transporter family DUF1844 PF08899.11 OQR89968.1 - 0.042 14.1 0.1 0.091 13.1 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1844) EppA_BapA PF07268.11 OQR89968.1 - 0.14 12.1 0.3 0.7 9.8 0.3 1.9 1 1 1 2 2 2 0 Exported protein precursor (EppA/BapA) Gly-zipper_Omp PF13488.6 OQR89968.1 - 0.5 10.4 9.1 0.79 9.8 9.1 1.3 1 0 0 1 1 1 0 Glycine zipper 2OG-FeII_Oxy_3 PF13640.6 OQR89969.1 - 1e-13 52.0 0.3 3e-13 50.5 0.0 1.9 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily DUF1348 PF07080.11 OQR89969.1 - 0.6 10.0 3.2 10 6.1 2.4 3.0 2 1 0 2 2 2 0 Protein of unknown function (DUF1348) NPL PF17800.1 OQR89970.1 - 3.6e-13 50.0 0.1 3.6e-13 50.0 0.1 2.0 2 0 0 2 2 2 1 Nucleoplasmin-like domain Nucleoplasmin PF03066.15 OQR89970.1 - 2.8e-05 24.5 0.2 6.8e-05 23.3 0.2 1.7 1 0 0 1 1 1 1 Nucleoplasmin/nucleophosmin domain CDC45 PF02724.14 OQR89970.1 - 0.15 10.3 7.3 0.16 10.2 7.3 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF4820 PF16091.5 OQR89970.1 - 2.2 7.6 11.2 3 7.2 11.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) RR_TM4-6 PF06459.12 OQR89970.1 - 3.8 7.3 15.2 4.7 7.0 15.2 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 GCFC PF07842.12 OQR89971.1 - 1.2e-07 31.7 1.2 6.2e-06 26.0 0.2 2.6 1 1 1 2 2 2 2 GC-rich sequence DNA-binding factor-like protein TMA7 PF09072.10 OQR89971.1 - 2.6 9.0 9.9 0.82 10.6 4.1 2.8 1 1 1 2 2 2 0 Translation machinery associated TMA7 Pkinase_Tyr PF07714.17 OQR89972.1 - 7.5e-14 51.6 0.0 1e-06 28.2 0.0 2.3 1 1 1 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 OQR89972.1 - 1.5e-10 40.9 0.0 9.8e-05 21.8 0.0 2.8 1 1 2 3 3 3 2 Protein kinase domain Adeno_E3_CR2 PF02439.15 OQR89972.1 - 9.2e-05 22.1 0.7 0.00017 21.3 0.7 1.4 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 Epiglycanin_C PF14654.6 OQR89972.1 - 0.0037 17.3 0.1 0.0079 16.2 0.1 1.5 1 0 0 1 1 1 1 Mucin, catalytic, TM and cytoplasmic tail region Glycophorin_A PF01102.18 OQR89972.1 - 0.025 14.8 0.1 0.047 13.9 0.1 1.4 1 0 0 1 1 1 0 Glycophorin A T4SS_CagC PF16943.5 OQR89972.1 - 0.028 14.6 0.8 0.051 13.8 0.8 1.3 1 0 0 1 1 1 0 Cag pathogenicity island, type IV secretory system EphA2_TM PF14575.6 OQR89972.1 - 0.057 14.3 0.0 0.097 13.6 0.0 1.3 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain SKG6 PF08693.10 OQR89972.1 - 8.3 5.9 11.2 0.16 11.4 4.3 1.7 2 0 0 2 2 2 0 Transmembrane alpha-helix domain BLOC1_2 PF10046.9 OQR89973.1 - 0.0085 16.4 0.4 0.13 12.5 0.0 2.7 2 0 0 2 2 2 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 bZIP_2 PF07716.15 OQR89973.1 - 0.02 14.9 19.4 0.017 15.2 6.3 2.5 2 0 0 2 2 2 0 Basic region leucine zipper bZIP_1 PF00170.21 OQR89973.1 - 0.04 14.0 16.9 0.26 11.4 2.8 2.7 2 0 0 2 2 2 0 bZIP transcription factor DUF5406 PF17400.2 OQR89973.1 - 0.057 13.8 0.0 0.86 10.0 0.0 2.7 3 0 0 3 3 3 0 Family of unknown function (DUF5406) Popeye PF04831.13 OQR89973.1 - 1.2 9.3 9.3 32 4.7 0.0 4.0 3 1 0 3 3 3 0 Popeye protein conserved region HAUS6_N PF14661.6 OQR89973.1 - 1.8 8.1 6.9 0.14 11.7 0.3 2.2 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus HNOB PF07700.15 OQR89974.1 - 0.019 14.9 0.1 0.029 14.3 0.1 1.3 1 0 0 1 1 1 0 Haem-NO-binding Prok-E2_B PF14461.6 OQR89976.1 - 0.012 15.3 0.0 0.023 14.4 0.0 1.4 1 0 0 1 1 1 0 Prokaryotic E2 family B Alba PF01918.21 OQR89976.1 - 0.1 12.4 0.0 0.25 11.2 0.0 1.6 1 0 0 1 1 1 0 Alba DUF4460 PF14687.6 OQR89984.1 - 0.0013 18.8 0.1 0.0039 17.2 0.1 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF4460) PT PF04886.12 OQR89985.1 - 0.31 10.6 15.7 0.92 9.1 15.7 1.8 1 1 0 1 1 1 0 PT repeat DUF4106 PF13388.6 OQR89985.1 - 1.4 8.0 3.4 2 7.6 3.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) Ion_trans_2 PF07885.16 OQR89986.1 - 8.2e-07 28.9 1.1 1.8e-06 27.8 0.5 1.9 1 1 0 1 1 1 1 Ion channel SK_channel PF03530.14 OQR89986.1 - 0.00015 21.7 1.1 0.00035 20.5 1.1 1.6 1 0 0 1 1 1 1 Calcium-activated SK potassium channel DUF2721 PF11026.8 OQR89986.1 - 0.021 14.7 0.6 0.021 14.7 0.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2721) Allexi_40kDa PF05549.11 OQR89986.1 - 0.029 13.9 1.3 0.046 13.2 1.3 1.3 1 0 0 1 1 1 0 Allexivirus 40kDa protein NapE PF06796.11 OQR89986.1 - 0.067 12.7 1.8 0.16 11.5 1.8 1.6 1 0 0 1 1 1 0 Periplasmic nitrate reductase protein NapE fn3 PF00041.21 OQR89987.1 - 1.5e-09 38.1 0.1 0.0048 17.2 0.0 3.8 2 2 0 2 2 2 2 Fibronectin type III domain PA PF02225.22 OQR89987.1 - 3.6e-07 30.1 0.0 8.9e-07 28.9 0.0 1.6 1 0 0 1 1 1 1 PA domain Pur_ac_phosph_N PF16656.5 OQR89987.1 - 0.13 12.9 0.0 3.1 8.5 0.1 2.6 2 0 0 2 2 2 0 Purple acid Phosphatase, N-terminal domain Arm PF00514.23 OQR89988.1 - 1.7e-21 75.5 44.5 0.00047 20.1 0.0 14.5 15 0 0 15 15 15 9 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 OQR89988.1 - 0.0001 22.6 1.9 0.24 11.8 0.1 4.9 4 0 0 4 4 4 1 HEAT repeats Arm_2 PF04826.13 OQR89988.1 - 0.0051 16.3 3.8 6.1 6.2 0.0 4.9 3 1 1 4 4 4 2 Armadillo-like Brix PF04427.18 OQR89990.1 - 8.4e-32 110.8 0.0 3.8e-31 108.7 0.0 2.0 2 0 0 2 2 2 1 Brix domain EF-hand_6 PF13405.6 OQR89990.1 - 3.9e-08 32.6 2.4 0.19 11.8 0.0 4.9 4 0 0 4 4 4 3 EF-hand domain EF-hand_1 PF00036.32 OQR89990.1 - 7.3e-08 31.4 0.1 1.8 8.3 0.0 4.9 4 0 0 4 4 4 3 EF hand EF-hand_7 PF13499.6 OQR89990.1 - 9.1e-07 29.2 1.9 0.16 12.4 0.0 4.7 3 1 1 4 4 4 3 EF-hand domain pair RIIa PF02197.17 OQR89990.1 - 0.00065 19.3 0.2 0.0043 16.7 0.2 2.3 1 1 0 1 1 1 1 Regulatory subunit of type II PKA R-subunit EF-hand_10 PF14788.6 OQR89990.1 - 0.077 12.9 0.0 0.8 9.6 0.0 2.6 2 0 0 2 2 2 0 EF hand Transposase_20 PF02371.16 OQR89990.1 - 0.12 12.7 0.0 0.3 11.4 0.0 1.6 1 0 0 1 1 1 0 Transposase IS116/IS110/IS902 family WD40 PF00400.32 OQR89992.1 - 2.2e-12 47.2 12.1 0.00016 22.4 0.3 6.8 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OQR89992.1 - 5.2e-05 23.5 0.0 1.4 9.2 0.0 4.3 4 1 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain GAS PF13851.6 OQR89992.1 - 0.0035 16.7 16.6 0.0035 16.7 16.6 5.2 3 1 2 5 5 5 1 Growth-arrest specific micro-tubule binding WD40_like PF17005.5 OQR89992.1 - 0.052 12.9 0.0 0.26 10.6 0.0 2.3 2 0 0 2 2 2 0 WD40-like domain TMF_DNA_bd PF12329.8 OQR89992.1 - 0.076 13.0 0.2 0.076 13.0 0.2 8.2 7 2 1 8 8 8 0 TATA element modulatory factor 1 DNA binding PQQ_3 PF13570.6 OQR89992.1 - 0.2 12.2 0.0 14 6.3 0.0 3.4 4 0 0 4 4 4 0 PQQ-like domain Carn_acyltransf PF00755.20 OQR89993.1 - 7.1e-170 566.5 0.0 8e-170 566.3 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase DUF1298 PF06974.13 OQR89993.1 - 0.013 15.4 0.0 0.026 14.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1298) Glyco_hydro_3 PF00933.21 OQR89994.1 - 6.9e-55 186.6 0.7 9.5e-55 186.2 0.1 1.5 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.22 OQR89994.1 - 1.3e-33 116.7 0.0 2.8e-33 115.6 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain FMO-like PF00743.19 OQR89994.1 - 2.8e-05 22.7 0.0 6.6e-05 21.5 0.0 1.6 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like Fn3-like PF14310.6 OQR89994.1 - 0.0042 17.2 0.0 0.016 15.3 0.0 2.0 1 0 0 1 1 1 1 Fibronectin type III-like domain Vps54 PF07928.12 OQR89995.1 - 2.2e-45 154.4 2.6 1e-44 152.3 2.6 2.2 1 0 0 1 1 1 1 Vps54-like protein Vps54_N PF10475.9 OQR89995.1 - 5.3e-18 65.3 16.8 1.8e-17 63.6 2.0 2.9 3 0 0 3 3 3 2 Vacuolar-sorting protein 54, of GARP complex DUF885 PF05960.11 OQR89995.1 - 0.0019 18.0 0.7 0.0082 15.8 0.2 2.2 1 1 0 2 2 2 1 Bacterial protein of unknown function (DUF885) COG2 PF06148.11 OQR89995.1 - 0.0075 16.4 4.6 0.0075 16.4 4.6 3.0 3 0 0 3 3 3 1 COG (conserved oligomeric Golgi) complex component, COG2 AATF-Che1 PF13339.6 OQR89995.1 - 7.2 7.3 12.9 1.4 9.6 0.3 3.7 2 1 1 3 3 3 0 Apoptosis antagonizing transcription factor Imm5 PF14423.6 OQR90000.1 - 4.5 7.5 8.2 2.2 8.5 5.7 1.7 1 1 0 1 1 1 0 Immunity protein Imm5 Kelch_3 PF13415.6 OQR90001.1 - 7.5e-08 32.5 0.3 0.098 13.0 0.1 4.0 4 0 0 4 4 4 3 Galactose oxidase, central domain Kelch_5 PF13854.6 OQR90001.1 - 2.8e-07 30.4 0.0 0.001 19.0 0.0 2.5 2 0 0 2 2 2 2 Kelch motif Kelch_4 PF13418.6 OQR90001.1 - 0.0003 20.7 0.1 0.73 9.9 0.0 2.7 2 0 0 2 2 2 2 Galactose oxidase, central domain Kelch_6 PF13964.6 OQR90001.1 - 0.00049 20.3 0.1 0.067 13.5 0.0 2.6 2 0 0 2 2 2 1 Kelch motif P_proprotein PF01483.20 OQR90001.1 - 0.084 12.9 0.1 0.23 11.5 0.1 1.8 1 0 0 1 1 1 0 Proprotein convertase P-domain IATP PF04568.12 OQR90002.1 - 9.5e-05 22.8 0.2 0.00013 22.3 0.2 1.3 1 0 0 1 1 1 1 Mitochondrial ATPase inhibitor, IATP YcxB PF14317.6 OQR90002.1 - 0.033 13.9 0.2 5.8 6.7 0.2 2.3 2 0 0 2 2 2 0 YcxB-like protein SpoVIF PF14069.6 OQR90002.1 - 0.052 13.3 0.2 1.5 8.6 0.0 2.2 2 0 0 2 2 2 0 Stage VI sporulation protein F HBS1_N PF08938.10 OQR90002.1 - 0.074 13.4 1.1 0.21 11.9 1.0 1.8 1 1 0 1 1 1 0 HBS1 N-terminus 4_1_CTD PF05902.13 OQR90003.1 - 0.045 13.8 0.0 0.092 12.8 0.0 1.5 1 0 0 1 1 1 0 4.1 protein C-terminal domain (CTD) Methyltr_RsmB-F PF01189.17 OQR90004.1 - 4.6e-15 55.8 0.0 1.5e-09 37.8 0.0 2.5 2 0 0 2 2 2 2 16S rRNA methyltransferase RsmB/F WD40 PF00400.32 OQR90005.1 - 9.5e-30 102.2 30.8 4.6e-07 30.4 0.2 8.7 8 0 0 8 8 8 6 WD domain, G-beta repeat Hira PF07569.11 OQR90005.1 - 9.7e-30 103.9 1.0 3.7e-24 85.7 0.0 2.3 2 0 0 2 2 2 2 TUP1-like enhancer of split ANAPC4_WD40 PF12894.7 OQR90005.1 - 1.3e-15 57.5 0.1 0.04 14.2 0.0 6.2 3 1 3 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 OQR90005.1 - 0.0023 17.0 0.4 0.54 9.2 0.0 2.9 2 1 0 2 2 2 2 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 OQR90005.1 - 0.033 14.1 2.1 15 5.7 0.1 4.2 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat TFIIIC_delta PF12657.7 OQR90005.1 - 0.079 12.9 0.2 0.079 12.9 0.2 2.5 3 1 0 3 3 3 0 Transcription factor IIIC subunit delta N-term IKI3 PF04762.12 OQR90005.1 - 0.19 9.7 1.3 2.8 5.8 0.0 2.3 1 1 1 2 2 2 0 IKI3 family Histone PF00125.24 OQR90006.1 - 1.3e-19 70.8 0.0 1.6e-19 70.5 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Histone_H2A_C PF16211.5 OQR90006.1 - 2.1e-11 43.4 1.8 9.2e-11 41.3 1.8 2.1 1 1 0 1 1 1 1 C-terminus of histone H2A CBFD_NFYB_HMF PF00808.23 OQR90006.1 - 0.00027 21.1 0.0 0.00036 20.7 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone ABC_tran PF00005.27 OQR90009.1 - 1.1e-51 175.0 0.1 5e-31 108.0 0.0 2.4 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 OQR90009.1 - 8.6e-47 160.1 36.6 1.5e-25 90.4 5.0 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.19 OQR90009.1 - 3.7e-09 36.4 0.0 0.012 15.1 0.2 3.5 2 2 1 3 3 3 3 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 OQR90009.1 - 6.8e-06 26.1 0.6 0.0018 18.4 0.1 2.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 OQR90009.1 - 0.00022 21.2 0.1 0.61 10.0 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_16 PF13191.6 OQR90009.1 - 0.00061 20.2 0.7 0.52 10.7 0.0 2.9 3 1 0 3 3 3 2 AAA ATPase domain AAA_29 PF13555.6 OQR90009.1 - 0.00072 19.2 0.2 0.4 10.5 0.1 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_21 PF13304.6 OQR90009.1 - 0.0012 18.7 0.1 0.9 9.3 0.2 3.4 2 1 1 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 OQR90009.1 - 0.0018 18.5 3.9 2 8.7 1.2 3.5 2 1 0 2 2 2 2 AAA domain DUF87 PF01935.17 OQR90009.1 - 0.016 15.3 1.6 0.092 12.8 0.2 2.2 2 0 0 2 2 2 0 Helicase HerA, central domain Dynamin_N PF00350.23 OQR90009.1 - 0.022 14.8 1.0 3.1 7.8 0.0 2.5 2 0 0 2 2 2 0 Dynamin family AAA_23 PF13476.6 OQR90009.1 - 0.023 15.2 0.1 0.32 11.5 0.0 2.2 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 OQR90009.1 - 0.023 15.1 0.1 5.2 7.5 0.0 2.6 2 0 0 2 2 2 0 RNA helicase DUF815 PF05673.13 OQR90009.1 - 0.026 13.7 0.0 3.6 6.7 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF815) IstB_IS21 PF01695.17 OQR90009.1 - 0.046 13.5 0.2 4.5 7.0 0.0 3.2 3 0 0 3 3 3 0 IstB-like ATP binding protein AAA_18 PF13238.6 OQR90009.1 - 0.077 13.5 0.1 5.3 7.6 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 OQR90009.1 - 0.14 11.7 0.3 7.2 6.1 0.0 2.5 2 0 0 2 2 2 0 P-loop containing dynein motor region Zeta_toxin PF06414.12 OQR90009.1 - 0.22 10.7 0.1 14 4.9 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin AAA_30 PF13604.6 OQR90009.1 - 0.63 9.7 3.0 15 5.2 1.0 3.0 2 1 0 2 2 2 0 AAA domain CGI-121 PF08617.10 OQR90010.1 - 1e-35 123.2 1.4 2.3e-35 122.1 1.4 1.6 1 0 0 1 1 1 1 Kinase binding protein CGI-121 RPAP3_C PF13877.6 OQR90010.1 - 1.8e-20 73.2 2.0 4.1e-20 72.1 2.0 1.6 1 0 0 1 1 1 1 Potential Monad-binding region of RPAP3 TPR_1 PF00515.28 OQR90010.1 - 1.7e-15 56.1 4.7 0.00014 21.5 0.1 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 OQR90010.1 - 2.5e-10 39.6 6.3 0.0013 18.7 0.2 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 OQR90010.1 - 2.7e-09 36.5 1.1 5.4e-06 26.0 0.1 3.0 2 1 1 3 3 3 2 TPR repeat TPR_16 PF13432.6 OQR90010.1 - 1.5e-07 31.9 4.5 1.6e-06 28.6 0.1 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 OQR90010.1 - 6.3e-07 29.1 3.3 0.15 12.4 0.0 4.2 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_9 PF13371.6 OQR90010.1 - 1.3e-05 25.3 0.7 0.0062 16.7 0.5 2.6 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.6 OQR90010.1 - 3.8e-05 23.8 2.3 0.0052 17.1 0.2 3.1 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_7 PF13176.6 OQR90010.1 - 0.0011 18.9 0.5 0.017 15.1 0.0 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 OQR90010.1 - 0.0012 18.9 2.9 4.2 7.5 0.1 3.8 2 1 1 3 3 3 2 Fis1 C-terminal tetratricopeptide repeat TPR_12 PF13424.6 OQR90010.1 - 0.0041 17.4 8.7 0.15 12.4 1.4 2.8 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.6 OQR90010.1 - 0.0077 16.7 2.7 0.019 15.5 0.2 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 OQR90010.1 - 0.014 16.1 0.9 13 6.9 0.2 3.2 2 1 1 3 3 3 0 Tetratricopeptide repeat Adeno_PVIII PF01310.18 OQR90010.1 - 0.2 11.2 0.4 1.7 8.2 0.0 2.1 2 0 0 2 2 2 0 Adenovirus hexon associated protein, protein VIII AA_permease_2 PF13520.6 OQR90013.1 - 1.9e-42 145.6 40.6 1.9e-42 145.6 40.6 1.6 1 1 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 OQR90013.1 - 2.9e-33 115.2 38.5 5.2e-33 114.3 38.5 1.4 1 0 0 1 1 1 1 Amino acid permease AA_permease_C PF13906.6 OQR90013.1 - 5.1e-11 42.5 4.7 5.1e-11 42.5 4.7 3.8 4 0 0 4 4 4 1 C-terminus of AA_permease PSS PF03034.15 OQR90013.1 - 0.0066 16.2 0.1 0.0066 16.2 0.1 1.8 2 1 0 2 2 2 1 Phosphatidyl serine synthase ECR1_N PF14382.6 OQR90014.1 - 3.9e-16 58.5 0.5 7.4e-16 57.7 0.5 1.5 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region KH_6 PF15985.5 OQR90014.1 - 3.5e-11 43.3 0.1 8e-11 42.1 0.1 1.7 1 0 0 1 1 1 1 KH domain GxGYxYP_C PF14323.6 OQR90014.1 - 0.042 13.7 0.1 0.18 11.7 0.0 1.8 2 0 0 2 2 2 0 GxGYxYP putative glycoside hydrolase C-terminal domain ATP-grasp PF02222.22 OQR90015.1 - 4.2e-54 182.7 0.0 6e-54 182.2 0.0 1.2 1 0 0 1 1 1 1 ATP-grasp domain PurK_C PF17769.1 OQR90015.1 - 2e-19 69.0 0.0 4.6e-19 67.8 0.0 1.7 1 0 0 1 1 1 1 Phosphoribosylaminoimidazole carboxylase C-terminal domain CPSase_L_D2 PF02786.17 OQR90015.1 - 7e-08 32.2 0.0 1e-07 31.7 0.0 1.2 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Dala_Dala_lig_C PF07478.13 OQR90015.1 - 1.1e-05 25.1 0.0 6.6e-05 22.5 0.0 2.0 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus AIRC PF00731.20 OQR90015.1 - 1.3e-05 24.8 0.2 4.9e-05 23.0 0.1 2.1 2 0 0 2 2 2 1 AIR carboxylase 2-Hacid_dh_C PF02826.19 OQR90015.1 - 0.025 14.0 0.0 0.059 12.7 0.0 1.6 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain S4 PF01479.25 OQR90017.1 - 6.5e-11 41.8 0.0 1.2e-10 40.9 0.0 1.5 1 0 0 1 1 1 1 S4 domain Ribosomal_S4 PF00163.19 OQR90017.1 - 4e-08 34.1 1.3 6.8e-08 33.3 1.3 1.5 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain CG-1 PF03859.16 OQR90022.1 - 6.4e-30 103.3 0.0 1e-29 102.6 0.0 1.3 1 0 0 1 1 1 1 CG-1 domain TIG PF01833.24 OQR90022.1 - 0.05 13.7 0.6 0.14 12.3 0.6 1.8 1 1 0 1 1 1 0 IPT/TIG domain WD40 PF00400.32 OQR90023.1 - 1.5e-19 69.9 6.2 3.8e-07 30.7 0.1 6.1 6 0 0 6 6 6 3 WD domain, G-beta repeat DEP PF00610.21 OQR90023.1 - 3.1e-17 62.4 0.0 1.2e-10 41.2 0.0 2.8 2 0 0 2 2 2 2 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) ANAPC4_WD40 PF12894.7 OQR90023.1 - 7.6e-07 29.3 1.1 0.012 15.9 0.2 4.1 3 1 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain FAM220 PF15487.6 OQR90023.1 - 1.3 8.5 6.4 2.4 7.7 6.4 1.3 1 0 0 1 1 1 0 FAM220 family WD40 PF00400.32 OQR90024.1 - 8.3e-23 80.3 16.9 0.019 15.8 0.0 11.1 11 0 0 11 11 11 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OQR90024.1 - 7.4e-07 29.4 0.1 0.37 11.1 0.0 6.3 4 2 3 7 7 7 1 Anaphase-promoting complex subunit 4 WD40 domain PQQ_3 PF13570.6 OQR90024.1 - 0.0035 17.8 0.2 10 6.8 0.0 5.3 5 0 0 5 5 5 1 PQQ-like domain WD40_like PF17005.5 OQR90024.1 - 0.0043 16.4 0.0 0.23 10.7 0.0 3.0 3 0 0 3 3 3 1 WD40-like domain YjeF_N PF03853.15 OQR90025.1 - 5.4e-39 133.8 0.0 6.7e-39 133.5 0.0 1.1 1 0 0 1 1 1 1 YjeF-related protein N-terminus LSM PF01423.22 OQR90028.1 - 2.5e-17 62.3 0.5 3.5e-17 61.9 0.5 1.2 1 0 0 1 1 1 1 LSM domain SPECT1 PF18680.1 OQR90028.1 - 0.058 13.1 0.4 0.071 12.8 0.4 1.1 1 0 0 1 1 1 0 Plasmodium host cell traversal SPECT1 SAM_1 PF00536.30 OQR90029.1 - 1.5e-10 41.3 1.6 4.5e-10 39.8 0.1 2.7 3 0 0 3 3 3 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 OQR90029.1 - 6.3e-09 35.8 1.2 2.1e-08 34.1 0.1 2.6 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) WD40 PF00400.32 OQR90030.1 - 1.7e-30 104.6 10.0 3.8e-06 27.5 0.1 6.2 7 0 0 7 7 7 5 WD domain, G-beta repeat Sof1 PF04158.14 OQR90030.1 - 1.6e-27 95.6 15.8 3.4e-27 94.5 15.8 1.6 1 0 0 1 1 1 1 Sof1-like domain ANAPC4_WD40 PF12894.7 OQR90030.1 - 1.3e-08 35.1 0.0 0.015 15.6 0.0 4.5 2 1 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 OQR90030.1 - 0.0019 17.2 0.1 0.51 9.2 0.0 2.6 2 1 0 2 2 2 2 WD40 region of Ge1, enhancer of mRNA-decapping protein MBR1 PF17058.5 OQR90030.1 - 0.047 14.0 5.3 0.11 12.8 5.3 1.6 1 0 0 1 1 1 0 Mitochondrial biogenesis regulation protein 1 zf-SAP30 PF13866.6 OQR90030.1 - 0.047 13.8 0.0 0.22 11.7 0.0 2.1 1 0 0 1 1 1 0 SAP30 zinc-finger EMP24_GP25L PF01105.24 OQR90034.1 - 3.1e-44 151.1 0.1 6.6e-44 150.0 0.1 1.5 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD EF-hand_1 PF00036.32 OQR90034.1 - 1e-20 71.6 5.3 8.3e-06 25.0 0.2 5.4 6 0 0 6 6 6 3 EF hand EF-hand_6 PF13405.6 OQR90034.1 - 4e-18 63.7 5.5 3.4e-05 23.4 0.0 5.3 5 0 0 5 5 5 3 EF-hand domain EF-hand_7 PF13499.6 OQR90034.1 - 2.5e-16 59.9 1.5 2.7e-10 40.6 0.0 4.0 4 0 0 4 4 4 2 EF-hand domain pair EF-hand_5 PF13202.6 OQR90034.1 - 6.3e-15 53.9 5.2 0.0012 18.2 0.0 5.2 5 0 0 5 5 5 3 EF hand EF-hand_8 PF13833.6 OQR90034.1 - 6.3e-09 35.5 7.4 0.35 10.7 0.0 5.5 5 1 1 6 6 6 3 EF-hand domain pair EF-hand_9 PF14658.6 OQR90034.1 - 0.0024 18.2 0.1 0.24 11.8 0.0 3.1 1 1 1 2 2 2 2 EF-hand domain Phage_hub_GP28 PF11110.8 OQR90034.1 - 0.031 14.2 0.1 0.073 13.0 0.1 1.6 1 0 0 1 1 1 0 Baseplate hub distal subunit EF-hand_4 PF12763.7 OQR90034.1 - 0.05 13.6 0.0 1 9.4 0.0 3.0 1 1 1 2 2 2 0 Cytoskeletal-regulatory complex EF hand Hemerythrin PF01814.23 OQR90035.1 - 1.2e-10 42.1 8.4 5.9e-10 39.9 6.9 2.2 2 1 0 2 2 2 1 Hemerythrin HHE cation binding domain Ribosomal_60s PF00428.19 OQR90036.1 - 1.5e-22 80.0 13.9 1.7e-22 79.8 13.9 1.0 1 0 0 1 1 1 1 60s Acidic ribosomal protein Adaptin_N PF01602.20 OQR90037.1 - 1.5e-97 327.4 6.0 2e-56 191.6 3.1 2.0 2 0 0 2 2 2 2 Adaptin N terminal region Cnd1 PF12717.7 OQR90037.1 - 5.2e-14 52.6 1.2 0.0052 16.8 0.1 4.6 4 0 0 4 4 4 3 non-SMC mitotic condensation complex subunit 1 Cnd3 PF12719.7 OQR90037.1 - 0.00013 21.3 1.2 0.053 12.7 0.1 2.5 2 0 0 2 2 2 2 Nuclear condensing complex subunits, C-term domain RTP1_C1 PF10363.9 OQR90037.1 - 0.0024 18.1 1.1 0.37 11.0 0.1 3.6 4 0 0 4 4 4 1 Required for nuclear transport of RNA pol II C-terminus 1 HEAT PF02985.22 OQR90037.1 - 0.021 15.1 0.1 51 4.5 0.0 4.9 4 1 0 4 4 4 0 HEAT repeat MMS19_C PF12460.8 OQR90037.1 - 0.24 10.5 3.3 0.21 10.7 0.3 2.4 2 1 0 2 2 2 0 RNAPII transcription regulator C-terminal HBS1_N PF08938.10 OQR90037.1 - 0.24 11.7 4.1 15 6.0 2.7 3.0 2 0 0 2 2 2 0 HBS1 N-terminus ABC_membrane PF00664.23 OQR90038.1 - 1.1e-34 120.3 14.5 1.6e-34 119.9 14.5 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region TPR_1 PF00515.28 OQR90042.1 - 1.4e-21 75.3 6.3 0.0028 17.4 0.2 6.7 6 0 0 6 6 6 6 Tetratricopeptide repeat TPR_2 PF07719.17 OQR90042.1 - 1.3e-17 62.4 11.0 0.00092 19.1 0.0 6.9 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_8 PF13181.6 OQR90042.1 - 1.6e-11 43.4 8.4 0.27 11.5 0.1 6.5 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_9 PF13371.6 OQR90042.1 - 4.9e-08 33.0 7.6 0.0038 17.3 0.1 5.8 5 1 1 6 6 5 1 Tetratricopeptide repeat TPR_19 PF14559.6 OQR90042.1 - 6.2e-07 29.8 9.8 0.0009 19.7 0.1 4.5 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 OQR90042.1 - 7.5e-05 23.2 12.7 1 10.4 0.0 7.0 5 2 2 7 7 6 1 Tetratricopeptide repeat NTP_transf_2 PF01909.23 OQR90042.1 - 0.0001 22.5 0.0 0.00067 19.9 0.0 2.3 2 0 0 2 2 2 1 Nucleotidyltransferase domain TPR_17 PF13431.6 OQR90042.1 - 0.00025 21.2 5.2 1.1 9.8 0.0 5.4 6 0 0 6 6 5 1 Tetratricopeptide repeat PAP_assoc PF03828.19 OQR90042.1 - 0.0012 19.1 0.0 0.0042 17.3 0.0 1.9 1 0 0 1 1 1 1 Cid1 family poly A polymerase TPR_16 PF13432.6 OQR90042.1 - 0.0015 19.1 12.9 0.017 15.8 0.1 4.6 4 1 1 5 5 4 1 Tetratricopeptide repeat SHNi-TPR PF10516.9 OQR90042.1 - 0.0024 17.3 1.3 7.6 6.1 0.0 4.9 6 0 0 6 6 6 1 SHNi-TPR TPR_12 PF13424.6 OQR90042.1 - 0.021 15.1 14.2 0.14 12.5 0.9 5.6 4 2 2 6 6 6 0 Tetratricopeptide repeat TPR_11 PF13414.6 OQR90042.1 - 0.025 14.3 10.0 8.1 6.2 0.0 5.5 4 2 3 7 7 7 0 TPR repeat TPR_6 PF13174.6 OQR90042.1 - 0.07 13.8 10.8 1.6 9.5 0.1 5.9 6 0 0 6 6 6 0 Tetratricopeptide repeat DUF3361 PF11841.8 OQR90042.1 - 0.093 12.7 0.0 0.33 10.9 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF3361) TPR_7 PF13176.6 OQR90042.1 - 0.59 10.3 10.4 3.4 7.9 0.0 5.6 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_15 PF13429.6 OQR90042.1 - 2.1 7.5 8.9 0.13 11.4 0.1 3.2 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_21 PF09976.9 OQR90042.1 - 2.7 7.7 8.0 3.6 7.3 0.2 3.4 4 0 0 4 4 3 0 Tetratricopeptide repeat-like domain DUF2968 PF11180.8 OQR90042.1 - 3.5 7.2 14.9 2.4 7.7 3.1 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2968) TMEM154 PF15102.6 OQR90043.1 - 0.069 13.1 0.1 0.11 12.3 0.1 1.4 1 1 0 1 1 1 0 TMEM154 protein family XPG_N PF00752.17 OQR90044.1 - 1e-30 106.2 0.0 2e-30 105.2 0.0 1.5 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.18 OQR90044.1 - 1.3e-27 96.0 0.0 3.1e-27 94.7 0.0 1.7 1 0 0 1 1 1 1 XPG I-region 5_3_exonuc PF01367.20 OQR90044.1 - 0.00018 22.0 0.0 0.00063 20.3 0.0 2.0 1 0 0 1 1 1 1 5'-3' exonuclease, C-terminal SAM fold Fe_dep_repr_C PF02742.15 OQR90044.1 - 0.01 15.9 0.0 5.8 7.1 0.0 2.5 2 0 0 2 2 2 0 Iron dependent repressor, metal binding and dimerisation domain 5_3_exonuc_N PF02739.16 OQR90044.1 - 0.014 15.3 0.0 0.43 10.5 0.0 2.4 2 1 0 2 2 2 0 5'-3' exonuclease, N-terminal resolvase-like domain Kinesin PF00225.23 OQR90045.1 - 3.1e-25 88.8 0.0 3.7e-25 88.6 0.0 1.0 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 OQR90045.1 - 4.8e-16 59.0 0.0 5.8e-16 58.8 0.0 1.0 1 0 0 1 1 1 1 Microtubule binding Bac_DnaA PF00308.18 OQR90045.1 - 0.018 14.9 0.0 0.025 14.4 0.0 1.2 1 0 0 1 1 1 0 Bacterial dnaA protein DUF1970 PF09301.10 OQR90045.1 - 0.13 12.5 0.0 0.26 11.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1970) zf-CCHC PF00098.23 OQR90046.1 - 2.1e-20 71.8 44.6 3.6e-06 26.8 3.5 6.2 6 0 0 6 6 6 5 Zinc knuckle zf-CCHC_4 PF14392.6 OQR90046.1 - 0.0034 17.1 39.7 0.15 11.8 0.3 6.2 6 1 1 7 7 7 5 Zinc knuckle zf-CCHC_3 PF13917.6 OQR90046.1 - 0.008 16.1 31.3 0.056 13.4 2.0 6.1 4 1 2 6 6 6 3 Zinc knuckle zf-CCHC_6 PF15288.6 OQR90046.1 - 0.08 12.8 28.1 0.34 10.8 0.7 4.4 4 1 1 5 5 5 0 Zinc knuckle Bromodomain PF00439.25 OQR90048.1 - 7.2e-40 134.9 1.2 1.1e-18 67.0 0.1 2.9 2 0 0 2 2 2 2 Bromodomain PHD PF00628.29 OQR90048.1 - 2.4e-13 49.7 17.8 4.8e-09 36.0 6.8 2.9 2 0 0 2 2 2 2 PHD-finger PDZ PF00595.24 OQR90048.1 - 1.9e-10 41.0 2.3 0.0029 17.9 1.0 5.4 6 0 0 6 6 6 2 PDZ domain PDZ_2 PF13180.6 OQR90048.1 - 1.3e-08 35.1 0.5 1 9.7 0.0 5.4 6 0 0 6 6 6 2 PDZ domain FYRC PF05965.14 OQR90048.1 - 2e-07 31.0 0.0 7.8e-07 29.2 0.0 2.1 1 0 0 1 1 1 1 F/Y rich C-terminus PDZ_6 PF17820.1 OQR90048.1 - 0.00024 20.9 0.1 9.5 6.2 0.0 4.8 4 0 0 4 4 4 1 PDZ domain PHD_2 PF13831.6 OQR90048.1 - 0.002 17.6 3.0 0.14 11.7 0.4 3.4 3 0 0 3 3 3 1 PHD-finger WHIM1 PF15612.6 OQR90048.1 - 0.006 16.1 0.0 0.014 15.0 0.0 1.7 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 1 FYRN PF05964.14 OQR90048.1 - 0.0085 15.9 0.0 0.023 14.5 0.0 1.7 1 0 0 1 1 1 1 F/Y-rich N-terminus DDT PF02791.17 OQR90048.1 - 0.027 14.8 0.5 0.093 13.1 0.5 2.0 1 0 0 1 1 1 0 DDT domain C1_2 PF03107.16 OQR90048.1 - 0.74 10.2 10.6 1.3 9.4 1.0 2.9 2 0 0 2 2 2 0 C1 domain Prok-RING_1 PF14446.6 OQR90048.1 - 1.9 8.5 15.8 0.26 11.3 3.0 3.6 3 0 0 3 3 3 0 Prokaryotic RING finger family 1 ADK_lid PF05191.14 OQR90048.1 - 2 8.5 6.1 1.1 9.3 3.0 2.3 2 0 0 2 2 2 0 Adenylate kinase, active site lid C1_1 PF00130.22 OQR90048.1 - 2.9 7.8 6.2 13 5.8 0.5 3.0 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Ubiquitin_4 PF18036.1 OQR90049.1 - 0.081 13.0 0.0 0.14 12.2 0.0 1.5 1 1 0 1 1 1 0 Ubiquitin-like domain ADH_zinc_N_2 PF13602.6 OQR90050.1 - 9e-18 65.6 0.0 1.5e-17 64.9 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 OQR90050.1 - 1.5e-10 41.2 0.2 3.3e-10 40.1 0.3 1.5 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 OQR90050.1 - 1.8e-05 24.5 0.0 4.1e-05 23.4 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain DUF2855 PF11017.8 OQR90050.1 - 0.034 13.9 0.3 0.41 10.3 0.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2855) TPR_2 PF07719.17 OQR90052.1 - 1.5e-11 43.4 10.1 0.00015 21.6 0.1 5.2 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_19 PF14559.6 OQR90052.1 - 1.3e-08 35.3 7.0 2.6e-05 24.7 0.7 4.5 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_14 PF13428.6 OQR90052.1 - 4.4e-08 33.3 3.6 0.59 11.1 0.1 5.0 2 1 3 5 5 5 3 Tetratricopeptide repeat TPR_17 PF13431.6 OQR90052.1 - 7.3e-08 32.3 3.5 0.043 14.2 0.1 4.9 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.6 OQR90052.1 - 1.2e-05 25.5 2.3 0.75 10.1 0.0 4.2 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.6 OQR90052.1 - 2.1e-05 24.9 4.8 0.14 12.9 0.1 4.8 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_16 PF13432.6 OQR90052.1 - 2.3e-05 25.0 1.4 0.0009 19.8 0.1 3.4 4 0 0 4 4 4 1 Tetratricopeptide repeat DUF5588 PF17826.1 OQR90052.1 - 0.00015 20.8 0.1 0.00038 19.5 0.1 1.6 1 1 0 1 1 1 1 Family of unknown function (DUF5588) TPR_1 PF00515.28 OQR90052.1 - 0.00021 21.0 3.9 0.077 12.9 0.1 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.6 OQR90052.1 - 0.00048 20.0 2.2 1.3 9.2 0.0 4.5 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_8 PF13181.6 OQR90052.1 - 0.00068 19.7 6.6 0.0028 17.7 0.1 4.2 5 1 0 5 5 4 1 Tetratricopeptide repeat RPN6_N PF18055.1 OQR90052.1 - 0.0036 17.7 1.3 1.2 9.6 0.1 2.5 2 0 0 2 2 2 2 26S proteasome regulatory subunit RPN6 N-terminal domain TPR_11 PF13414.6 OQR90052.1 - 0.0065 16.1 4.1 1.4 8.7 0.2 3.7 2 1 1 3 3 3 2 TPR repeat TPR_9 PF13371.6 OQR90052.1 - 0.021 14.9 0.1 0.19 11.9 0.0 2.5 2 1 1 3 3 3 0 Tetratricopeptide repeat NARP1 PF12569.8 OQR90052.1 - 0.035 13.0 1.5 1.1 8.0 0.0 2.3 1 1 1 2 2 2 0 NMDA receptor-regulated protein 1 Wzy_C_2 PF11846.8 OQR90052.1 - 0.16 11.9 0.2 0.9 9.4 0.1 2.0 1 1 1 2 2 2 0 Virulence factor membrane-bound polymerase, C-terminal DUF5438 PF17506.2 OQR90054.1 - 0.1 13.0 0.1 0.99 9.8 0.1 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5438) AAA_12 PF13087.6 OQR90055.1 - 7.4e-59 198.7 0.0 8.4e-59 198.6 0.0 1.0 1 0 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.6 OQR90055.1 - 0.11 12.3 0.1 0.25 11.2 0.1 1.7 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain Sugar_tr PF00083.24 OQR90066.1 - 1.6e-12 47.1 5.2 2.4e-10 39.9 5.1 2.1 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OQR90066.1 - 3.3e-12 46.0 11.6 3.4e-11 42.7 11.6 2.0 1 1 0 1 1 1 1 Major Facilitator Superfamily C2 PF00168.30 OQR90067.1 - 1.7e-12 47.5 0.3 5.7e-12 45.8 0.0 2.0 2 0 0 2 2 2 1 C2 domain PTR2 PF00854.21 OQR90076.1 - 1.7e-60 204.9 7.4 5.2e-60 203.4 7.4 1.7 1 1 0 1 1 1 1 POT family 7TM_GPCR_Srh PF10318.9 OQR90076.1 - 0.033 13.2 0.3 0.033 13.2 0.3 2.6 2 1 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srh PAN_4 PF14295.6 OQR90079.1 - 1e-20 73.4 23.6 4.8e-07 29.6 3.4 3.7 3 0 0 3 3 3 3 PAN domain Med9 PF07544.13 OQR90079.1 - 0.12 12.5 0.0 18 5.5 0.0 2.8 3 0 0 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 DUF1657 PF07870.11 OQR90079.1 - 0.14 12.1 5.5 13 5.8 0.1 4.0 4 0 0 4 4 4 0 Protein of unknown function (DUF1657) Whib PF02467.16 OQR90079.1 - 0.24 12.0 10.8 16 6.1 0.4 3.4 3 0 0 3 3 3 0 Transcription factor WhiB zf-CpG_bind_C PF12269.8 OQR90079.1 - 0.73 9.6 10.6 2.2 8.0 1.2 2.6 1 1 1 2 2 2 0 CpG binding protein zinc finger C terminal domain Arc_trans_TRASH PF08394.10 OQR90079.1 - 0.88 10.0 7.8 2 8.8 0.1 3.4 3 0 0 3 3 3 0 Archaeal TRASH domain MFS_1 PF07690.16 OQR90080.1 - 4.7e-36 124.4 43.6 2.1e-32 112.4 31.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily WD40 PF00400.32 OQR90091.1 - 8.2e-35 118.2 12.5 6.2e-08 33.2 0.0 6.8 7 0 0 7 7 7 6 WD domain, G-beta repeat WD40_like PF17005.5 OQR90091.1 - 8.5e-07 28.6 1.5 9.8e-07 28.4 0.8 1.4 2 0 0 2 2 2 1 WD40-like domain ANAPC4_WD40 PF12894.7 OQR90091.1 - 3.8e-05 23.9 0.3 0.55 10.6 0.0 4.6 2 1 3 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain Mcl1_mid PF12341.8 OQR90091.1 - 0.031 13.6 0.0 0.09 12.1 0.0 1.7 2 0 0 2 2 2 0 Minichromosome loss protein, Mcl1, middle region RAB3GAP2_N PF14655.6 OQR90091.1 - 0.059 12.6 0.0 0.097 11.9 0.0 1.3 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus PQQ PF01011.21 OQR90091.1 - 0.1 12.6 0.5 2.6 8.1 0.1 3.0 4 0 0 4 4 4 0 PQQ enzyme repeat Rtf2 PF04641.12 OQR90092.1 - 3.4e-50 170.9 10.1 9.7e-50 169.4 10.1 1.6 1 1 0 1 1 1 1 Rtf2 RING-finger zf-Nse PF11789.8 OQR90092.1 - 0.00021 21.1 0.7 0.7 9.8 0.0 2.5 2 0 0 2 2 2 2 Zinc-finger of the MIZ type in Nse subunit zf-RanBP PF00641.18 OQR90092.1 - 0.078 12.3 0.2 0.14 11.5 0.2 1.5 1 0 0 1 1 1 0 Zn-finger in Ran binding protein and others zf-RING_UBOX PF13445.6 OQR90092.1 - 0.088 12.9 1.0 0.19 11.7 1.0 1.7 1 0 0 1 1 1 0 RING-type zinc-finger zf-NOSIP PF15906.5 OQR90092.1 - 0.11 12.6 0.0 0.23 11.6 0.0 1.5 1 0 0 1 1 1 0 Zinc-finger of nitric oxide synthase-interacting protein Nup160 PF11715.8 OQR90094.1 - 0.0011 17.7 0.5 0.25 9.9 0.0 2.2 2 0 0 2 2 2 2 Nucleoporin Nup120/160 WD40 PF00400.32 OQR90094.1 - 0.015 16.1 6.4 0.29 12.1 0.1 4.3 4 0 0 4 4 4 0 WD domain, G-beta repeat PQQ_3 PF13570.6 OQR90094.1 - 0.091 13.3 5.4 34 5.1 0.0 5.1 5 1 0 5 5 5 0 PQQ-like domain POX PF07526.11 OQR90095.1 - 0.05 14.2 0.1 0.05 14.2 0.1 1.2 1 0 0 1 1 1 0 Associated with HOX TPR_1 PF00515.28 OQR90096.1 - 0.018 14.9 0.0 0.11 12.3 0.0 2.4 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_2 PF07719.17 OQR90096.1 - 0.096 12.8 0.0 1.4 9.2 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat Ras PF00071.22 OQR90107.1 - 7.5e-49 165.4 0.0 9.7e-49 165.1 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OQR90107.1 - 6e-30 103.9 0.0 1.6e-29 102.6 0.0 1.6 1 1 1 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OQR90107.1 - 6.9e-09 35.4 0.0 8.3e-09 35.1 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 OQR90107.1 - 8.2e-05 22.7 0.0 0.0002 21.4 0.0 1.6 1 1 1 2 2 2 1 50S ribosome-binding GTPase RNA_helicase PF00910.22 OQR90107.1 - 0.00011 22.5 0.2 0.00086 19.7 0.1 2.2 1 1 0 1 1 1 1 RNA helicase Gtr1_RagA PF04670.12 OQR90107.1 - 0.0083 15.5 0.0 0.012 15.0 0.0 1.3 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 OQR90107.1 - 0.024 14.5 0.1 1.8 8.4 0.1 2.1 2 0 0 2 2 2 0 RsgA GTPase AAA_16 PF13191.6 OQR90107.1 - 0.063 13.7 0.0 0.11 12.9 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain ArgoMid PF16487.5 OQR90107.1 - 0.073 13.3 0.1 0.13 12.5 0.1 1.4 1 0 0 1 1 1 0 Mid domain of argonaute TsaE PF02367.17 OQR90107.1 - 0.11 12.5 0.2 0.66 10.0 0.2 2.0 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_7 PF12775.7 OQR90107.1 - 0.14 11.7 0.1 0.22 11.0 0.1 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_33 PF13671.6 OQR90107.1 - 0.15 12.2 0.1 0.28 11.3 0.1 1.5 1 0 0 1 1 1 0 AAA domain GDH_N PF12466.8 OQR90108.1 - 0.016 15.4 0.4 1.8 8.9 0.0 3.1 3 0 0 3 3 3 0 Glutamate dehydrogenase N terminal Attachment_P66 PF11263.8 OQR90108.1 - 0.073 12.3 2.3 0.21 10.8 0.5 2.2 2 0 0 2 2 2 0 Borrelia burgdorferi attachment protein P66 SR-25 PF10500.9 OQR90109.1 - 0.69 9.5 30.7 0.99 9.0 30.7 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein EMG1 PF03587.14 OQR90132.1 - 1.2e-68 230.6 0.0 2.3e-68 229.7 0.0 1.4 1 0 0 1 1 1 1 EMG1/NEP1 methyltransferase Peptidase_C69 PF03577.15 OQR90132.1 - 1e-45 156.4 0.1 3.4e-45 154.7 0.1 1.9 1 1 0 1 1 1 1 Peptidase family C69 Phage_attach PF05354.11 OQR90132.1 - 0.11 12.4 0.0 0.31 10.9 0.0 1.8 1 0 0 1 1 1 0 Phage Head-Tail Attachment LSM PF01423.22 OQR90133.1 - 8.1e-15 54.3 0.1 1e-14 54.0 0.1 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 OQR90133.1 - 7.5e-05 22.8 0.0 9.7e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 Ataxin 2 SM domain SRP68 PF16969.5 OQR90134.1 - 2.9e-121 406.2 8.0 4.6e-121 405.6 8.0 1.3 1 1 0 1 1 1 1 RNA-binding signal recognition particle 68 PTS_IIA PF02255.16 OQR90134.1 - 0.078 13.0 2.4 0.97 9.5 0.2 2.7 2 0 0 2 2 2 0 PTS system, Lactose/Cellobiose specific IIA subunit TipAS PF07739.13 OQR90134.1 - 0.32 11.6 5.3 4.8 7.8 0.5 2.9 3 0 0 3 3 3 0 TipAS antibiotic-recognition domain TPR_2 PF07719.17 OQR90134.1 - 1.6 9.0 11.4 2.3 8.5 1.4 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat Bin3 PF06859.12 OQR90136.1 - 8.8e-40 135.7 0.2 1.7e-39 134.8 0.0 1.6 2 0 0 2 2 1 1 Bicoid-interacting protein 3 (Bin3) Methyltransf_31 PF13847.6 OQR90136.1 - 1.6e-10 41.0 0.0 5.5e-07 29.5 0.1 2.3 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.12 OQR90136.1 - 5.5e-10 39.9 0.1 2e-08 34.9 0.1 2.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OQR90136.1 - 2.9e-09 37.5 0.0 4.4e-06 27.3 0.0 2.4 1 1 1 2 2 2 2 Methyltransferase domain Methyltransf_23 PF13489.6 OQR90136.1 - 3.3e-08 33.5 0.0 5.2e-08 32.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OQR90136.1 - 5.9e-07 30.1 0.0 0.0028 18.3 0.0 2.4 1 1 1 2 2 2 2 Methyltransferase domain Methyltransf_4 PF02390.17 OQR90136.1 - 0.00091 18.7 0.0 0.0019 17.7 0.0 1.5 1 0 0 1 1 1 1 Putative methyltransferase PCMT PF01135.19 OQR90136.1 - 0.014 15.2 0.0 0.022 14.5 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MTS PF05175.14 OQR90136.1 - 0.019 14.5 0.0 0.031 13.8 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Ubie_methyltran PF01209.18 OQR90136.1 - 0.044 13.1 0.0 0.078 12.3 0.0 1.4 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_18 PF12847.7 OQR90136.1 - 0.053 13.4 0.0 0.089 12.7 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Swi3 PF07962.12 OQR90144.1 - 2.9e-17 62.4 0.0 4.8e-17 61.7 0.0 1.3 1 0 0 1 1 1 1 Replication Fork Protection Component Swi3 TPR_14 PF13428.6 OQR90145.1 - 1.3e-07 31.8 22.0 0.1 13.5 0.3 9.4 7 1 3 10 10 10 2 Tetratricopeptide repeat TPR_8 PF13181.6 OQR90145.1 - 3.7e-06 26.7 1.5 0.0063 16.6 0.2 4.8 4 0 0 4 4 4 1 Tetratricopeptide repeat Suf PF05843.14 OQR90145.1 - 5.4e-06 26.6 3.9 0.019 15.0 0.2 2.8 3 0 0 3 3 3 2 Suppressor of forked protein (Suf) TPR_7 PF13176.6 OQR90145.1 - 1.6e-05 24.6 3.2 0.05 13.6 0.1 4.5 4 0 0 4 4 4 2 Tetratricopeptide repeat RPN7 PF10602.9 OQR90145.1 - 0.00024 20.9 1.6 0.1 12.3 0.0 2.8 3 0 0 3 3 3 2 26S proteasome subunit RPN7 Mad3_BUB1_I PF08311.12 OQR90145.1 - 0.0016 18.4 7.9 0.031 14.2 0.1 4.4 3 2 1 4 4 4 1 Mad3/BUB1 homology region 1 TPR_15 PF13429.6 OQR90145.1 - 0.0019 17.5 10.1 0.11 11.7 3.2 3.8 2 1 3 5 5 5 3 Tetratricopeptide repeat TPR_12 PF13424.6 OQR90145.1 - 0.0019 18.4 3.7 0.08 13.2 0.1 4.0 4 1 0 4 4 4 1 Tetratricopeptide repeat NRDE-2 PF08424.10 OQR90145.1 - 0.0056 15.9 4.5 0.4 9.8 0.5 4.2 2 2 2 4 4 4 1 NRDE-2, necessary for RNA interference TPR_2 PF07719.17 OQR90145.1 - 0.0065 16.5 0.6 0.0065 16.5 0.6 5.9 7 0 0 7 7 6 1 Tetratricopeptide repeat TPR_19 PF14559.6 OQR90145.1 - 0.085 13.4 7.3 16 6.1 0.3 4.5 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_1 PF00515.28 OQR90145.1 - 0.11 12.4 0.2 0.11 12.4 0.2 4.5 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_16 PF13432.6 OQR90145.1 - 0.22 12.2 7.1 30 5.4 0.1 4.6 3 1 1 4 4 4 0 Tetratricopeptide repeat PTB PF08416.13 OQR90150.1 - 0.059 13.5 0.1 0.22 11.7 0.1 2.0 1 0 0 1 1 1 0 Phosphotyrosine-binding domain DUF3361 PF11841.8 OQR90150.1 - 0.28 11.1 3.5 2.5 8.0 0.6 3.3 2 1 0 2 2 2 0 Domain of unknown function (DUF3361) Ran_BP1 PF00638.18 OQR90155.1 - 5.9e-38 129.9 0.8 9.2e-38 129.2 0.8 1.3 1 0 0 1 1 1 1 RanBP1 domain WH1 PF00568.23 OQR90155.1 - 0.0022 17.9 0.5 0.0079 16.1 0.5 1.9 1 1 0 1 1 1 1 WH1 domain PMI_typeI PF01238.21 OQR90156.1 - 4.5e-108 361.8 0.0 6.2e-108 361.3 0.0 1.2 1 0 0 1 1 1 1 Phosphomannose isomerase type I AAA PF00004.29 OQR90156.1 - 5.7e-15 55.9 0.0 1.8e-14 54.3 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 OQR90156.1 - 4.6e-05 23.4 0.0 0.0001 22.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 OQR90156.1 - 0.00066 20.1 0.0 0.0023 18.3 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain Cupin_1 PF00190.22 OQR90156.1 - 0.0019 17.8 0.0 0.0053 16.4 0.0 1.7 1 0 0 1 1 1 1 Cupin RuvB_N PF05496.12 OQR90156.1 - 0.002 17.9 0.1 0.0055 16.5 0.1 1.7 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 OQR90156.1 - 0.0024 18.2 0.0 0.0075 16.5 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.6 OQR90156.1 - 0.0045 17.3 0.3 0.23 11.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.21 OQR90156.1 - 0.0075 15.7 0.1 0.014 14.8 0.1 1.3 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 OQR90156.1 - 0.0078 16.0 0.0 0.015 15.0 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein NTPase_1 PF03266.15 OQR90156.1 - 0.011 15.7 0.8 5.2 6.9 0.1 2.6 2 0 0 2 2 2 0 NTPase AAA_33 PF13671.6 OQR90156.1 - 0.024 14.8 0.0 0.048 13.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain Cupin_2 PF07883.11 OQR90156.1 - 0.025 14.3 0.0 3.3 7.5 0.0 2.6 2 0 0 2 2 2 0 Cupin domain TIP49 PF06068.13 OQR90156.1 - 0.03 13.5 0.0 0.054 12.7 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_18 PF13238.6 OQR90156.1 - 0.043 14.4 0.0 0.16 12.6 0.0 2.0 1 0 0 1 1 1 0 AAA domain AraC_binding PF02311.19 OQR90156.1 - 0.058 13.3 0.2 8.4 6.3 0.0 3.0 3 0 0 3 3 3 0 AraC-like ligand binding domain AAA_30 PF13604.6 OQR90156.1 - 0.058 13.1 0.1 0.15 11.8 0.1 1.6 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 OQR90156.1 - 0.067 12.7 0.0 0.14 11.6 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region PhoH PF02562.16 OQR90156.1 - 0.21 11.0 1.3 0.48 9.8 0.2 1.9 2 0 0 2 2 2 0 PhoH-like protein Vps53_N PF04100.12 OQR90157.1 - 5e-13 48.8 0.3 5.7e-13 48.6 0.3 1.0 1 0 0 1 1 1 1 Vps53-like, N-terminal Vps54_N PF10475.9 OQR90157.1 - 0.0017 17.7 0.2 0.0019 17.5 0.2 1.0 1 0 0 1 1 1 1 Vacuolar-sorting protein 54, of GARP complex HSCB_C PF07743.13 OQR90157.1 - 0.032 14.7 0.6 0.048 14.2 0.6 1.4 1 0 0 1 1 1 0 HSCB C-terminal oligomerisation domain Orthopox_F6 PF06601.12 OQR90157.1 - 0.045 13.9 0.2 0.13 12.4 0.1 1.7 2 0 0 2 2 2 0 Orthopoxvirus F6 protein DUF2730 PF10805.8 OQR90157.1 - 0.08 13.0 0.1 0.23 11.6 0.0 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2730) SLC35F PF06027.12 OQR90158.1 - 2.4e-76 257.1 24.0 2.9e-76 256.9 24.0 1.0 1 0 0 1 1 1 1 Solute carrier family 35 EamA PF00892.20 OQR90158.1 - 7.1e-11 42.4 27.7 7.1e-06 26.2 12.6 2.2 2 0 0 2 2 2 2 EamA-like transporter family CRT-like PF08627.10 OQR90158.1 - 2.4e-10 39.9 3.9 2.4e-10 39.9 3.9 2.3 2 1 0 2 2 2 1 CRT-like, chloroquine-resistance transporter-like UAA PF08449.11 OQR90158.1 - 4.7e-07 29.3 21.1 6.3e-07 28.9 21.1 1.1 1 0 0 1 1 1 1 UAA transporter family Condensin2nSMC PF12422.8 OQR90160.1 - 0.02 15.1 1.9 0.4 10.9 1.9 2.6 1 1 0 1 1 1 0 Condensin II non structural maintenance of chromosomes subunit BAR_3 PF16746.5 OQR90160.1 - 0.095 12.4 2.6 0.16 11.7 2.6 1.3 1 0 0 1 1 1 0 BAR domain of APPL family DUF4162 PF13732.6 OQR90160.1 - 0.17 12.6 0.4 1.7 9.4 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4162) Peptidase_M20 PF01546.28 OQR90163.1 - 2.8e-58 197.1 0.0 6.1e-29 101.2 0.0 2.1 2 0 0 2 2 2 2 Peptidase family M20/M25/M40 M20_dimer PF07687.14 OQR90163.1 - 3.2e-32 110.7 0.0 8.6e-16 57.8 0.0 2.3 2 0 0 2 2 2 2 Peptidase dimerisation domain NifU PF01106.17 OQR90163.1 - 0.011 15.8 0.1 3.7 7.8 0.0 2.6 2 0 0 2 2 2 0 NifU-like domain DUF1816 PF08846.10 OQR90163.1 - 0.054 13.5 0.0 6.6 6.8 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1816) DUF1942 PF09167.11 OQR90164.1 - 0.051 13.5 0.7 0.21 11.5 0.1 2.3 3 0 0 3 3 3 0 Domain of unknown function (DUF1942) Glyco_hydro81C PF17652.1 OQR90166.1 - 1.3e-84 284.5 2.3 1.8e-84 284.0 2.3 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 C-terminal domain Glyco_hydro_81 PF03639.13 OQR90166.1 - 1.8e-30 106.2 0.0 2.8e-30 105.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 N-terminal domain Ribonuc_red_sm PF00268.21 OQR90167.1 - 3e-114 381.2 0.9 3.6e-114 381.0 0.9 1.0 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain DUF4744 PF15918.5 OQR90167.1 - 0.16 12.8 0.0 0.31 11.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4744) GLEYA PF10528.9 OQR90170.1 - 0.15 12.5 0.4 0.69 10.4 0.5 1.9 2 0 0 2 2 2 0 GLEYA domain DnaJ PF00226.31 OQR90186.1 - 6.9e-23 80.6 1.9 1e-22 80.0 0.2 2.0 2 0 0 2 2 2 1 DnaJ domain Claudin_2 PF13903.6 OQR90187.1 - 0.0017 18.1 2.1 0.3 10.8 0.3 2.4 2 0 0 2 2 2 2 PMP-22/EMP/MP20/Claudin tight junction SYS1 PF09801.9 OQR90187.1 - 0.056 13.6 3.7 0.15 12.2 3.7 1.9 1 1 0 1 1 1 0 Integral membrane protein S linking to the trans Golgi network LUC7 PF03194.15 OQR90192.1 - 1.5e-78 263.9 1.2 2.1e-78 263.5 1.2 1.3 1 1 0 1 1 1 1 LUC7 N_terminus Mu-like_Pro PF10123.9 OQR90192.1 - 0.063 12.8 3.4 0.087 12.4 3.4 1.1 1 0 0 1 1 1 0 Mu-like prophage I protein Mistic PF11458.8 OQR90192.1 - 0.25 11.3 1.9 1.8 8.6 1.3 2.2 1 1 1 2 2 2 0 Membrane-integrating protein Mistic TBCA PF02970.16 OQR90192.1 - 0.98 9.8 7.1 7.7 6.9 1.1 2.5 1 1 1 2 2 2 0 Tubulin binding cofactor A DUF4778 PF16008.5 OQR90192.1 - 1 9.4 12.3 0.99 9.4 7.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4778) Pkinase_Tyr PF07714.17 OQR90195.1 - 9.8e-21 74.2 0.0 1.3e-20 73.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OQR90195.1 - 3.6e-20 72.4 0.0 4.7e-20 72.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain PALP PF00291.25 OQR90196.1 - 2.4e-25 89.5 0.0 3.4e-25 89.0 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme CBS PF00571.28 OQR90196.1 - 1.1e-13 51.4 0.1 1.6e-07 31.7 0.0 2.8 2 0 0 2 2 2 2 CBS domain Abhydrolase_6 PF12697.7 OQR90197.1 - 6.4e-09 36.7 0.0 9.1e-09 36.2 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 OQR90197.1 - 5e-05 23.1 0.0 8.6e-05 22.3 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF1057 PF06342.12 OQR90197.1 - 9.4e-05 21.6 0.0 0.00015 20.9 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1057) Thioesterase PF00975.20 OQR90197.1 - 0.00065 19.9 0.0 0.0009 19.4 0.0 1.2 1 0 0 1 1 1 1 Thioesterase domain DUF1842 PF08896.10 OQR90197.1 - 0.086 13.1 0.1 13 6.0 0.0 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF1842) Gly_transf_sug PF04488.15 OQR90198.1 - 2.7e-14 53.6 0.1 6.6e-14 52.3 0.1 1.7 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.12 OQR90198.1 - 4.1e-08 32.9 0.1 5.7e-08 32.5 0.1 1.3 1 0 0 1 1 1 1 Capsular polysaccharide synthesis protein START PF01852.19 OQR90199.1 - 6e-24 84.6 0.1 7e-24 84.4 0.1 1.1 1 0 0 1 1 1 1 START domain Methyltransf_16 PF10294.9 OQR90200.1 - 4.7e-20 72.0 0.0 5.9e-20 71.7 0.0 1.1 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_12 PF08242.12 OQR90200.1 - 0.0067 17.2 0.0 0.01 16.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OQR90200.1 - 0.011 15.6 0.0 0.013 15.3 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain DUF938 PF06080.12 OQR90200.1 - 0.052 13.3 0.0 0.067 12.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF938) DUF3696 PF12476.8 OQR90200.1 - 0.09 13.2 0.0 0.39 11.2 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3696) START PF01852.19 OQR90201.1 - 5.7e-23 81.4 0.0 7.3e-23 81.1 0.0 1.1 1 0 0 1 1 1 1 START domain Polyketide_cyc2 PF10604.9 OQR90201.1 - 0.16 12.3 0.0 1.2 9.3 0.0 2.2 2 1 0 2 2 2 0 Polyketide cyclase / dehydrase and lipid transport SelR PF01641.18 OQR90212.1 - 2.1e-46 157.0 0.0 2.4e-46 156.8 0.0 1.0 1 0 0 1 1 1 1 SelR domain zinc_ribbon_10 PF10058.9 OQR90212.1 - 0.0014 18.3 0.1 0.87 9.4 0.0 2.3 2 0 0 2 2 2 2 Predicted integral membrane zinc-ribbon metal-binding protein TF_Zn_Ribbon PF08271.12 OQR90212.1 - 0.023 14.2 1.9 3.5 7.2 0.3 2.4 2 0 0 2 2 2 0 TFIIB zinc-binding Zn_ribbon_recom PF13408.6 OQR90212.1 - 0.45 11.1 3.3 18 6.0 0.4 2.3 2 0 0 2 2 2 0 Recombinase zinc beta ribbon domain CMS1 PF14617.6 OQR90213.1 - 8.4e-32 110.5 0.5 1e-31 110.2 0.5 1.1 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit DEAD PF00270.29 OQR90213.1 - 0.0022 17.8 0.0 0.0034 17.2 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase SpoIIP PF07454.11 OQR90213.1 - 0.021 14.3 1.0 1.1 8.7 0.1 2.1 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) FAM194 PF14977.6 OQR90215.1 - 6.3e-11 42.0 0.0 9.4e-11 41.4 0.0 1.3 1 0 0 1 1 1 1 FAM194 protein DIX PF00778.17 OQR90216.1 - 1.4e-07 31.3 0.0 2.4e-07 30.5 0.0 1.4 1 0 0 1 1 1 1 DIX domain DnaJ PF00226.31 OQR90216.1 - 1.1e-05 25.4 0.0 6.1e-05 23.1 0.0 2.2 2 0 0 2 2 2 1 DnaJ domain GYF_2 PF14237.6 OQR90216.1 - 0.043 13.6 0.0 0.11 12.3 0.0 1.7 1 0 0 1 1 1 0 GYF domain 2 RabGAP-TBC PF00566.18 OQR90217.1 - 8.2e-44 149.8 1.0 8.2e-44 149.8 1.0 2.6 3 0 0 3 3 3 1 Rab-GTPase-TBC domain PH PF00169.29 OQR90217.1 - 1.4e-15 57.7 0.6 2.5e-15 56.8 0.6 1.5 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 OQR90217.1 - 0.0022 18.4 3.9 0.012 16.0 3.9 2.3 1 1 0 1 1 1 1 Pleckstrin homology domain PH_3 PF14593.6 OQR90217.1 - 0.021 14.9 1.1 0.056 13.6 1.1 1.8 1 0 0 1 1 1 0 PH domain PH_13 PF16652.5 OQR90217.1 - 0.041 13.7 0.1 0.041 13.7 0.1 1.7 2 0 0 2 2 2 0 Pleckstrin homology domain PH_6 PF15406.6 OQR90217.1 - 0.11 12.7 0.0 0.23 11.7 0.0 1.5 1 0 0 1 1 1 0 Pleckstrin homology domain CIAPIN1 PF05093.13 OQR90218.1 - 1e-15 58.0 17.0 3.9e-12 46.6 3.8 2.5 1 1 1 2 2 2 2 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis Dynein_C PF18199.1 OQR90219.1 - 4.2e-97 325.1 0.0 8.6e-97 324.0 0.0 1.5 2 0 0 2 2 2 1 Dynein heavy chain C-terminal domain AAA_lid_11 PF18198.1 OQR90219.1 - 5.4e-61 205.2 0.0 8.8e-61 204.5 0.0 1.3 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 OQR90219.1 - 6.4e-43 145.6 0.0 6.1e-42 142.5 0.0 2.2 2 0 0 2 2 2 1 Dynein heavy chain region D6 P-loop domain Rotamase PF00639.21 OQR90220.1 - 1.3e-23 83.7 0.0 1.5e-23 83.6 0.0 1.0 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_3 PF13616.6 OQR90220.1 - 4.7e-22 78.7 0.0 5.2e-22 78.6 0.0 1.0 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_2 PF13145.6 OQR90220.1 - 0.0001 23.1 0.0 0.00012 22.9 0.0 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain AAA_8 PF12780.7 OQR90221.1 - 9.9e-90 300.4 0.0 2.1e-89 299.3 0.0 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 AAA_9 PF12781.7 OQR90221.1 - 3.1e-87 291.3 0.4 3.1e-87 291.3 0.4 2.9 3 0 0 3 3 3 1 ATP-binding dynein motor region MT PF12777.7 OQR90221.1 - 5.1e-52 177.0 16.6 5.1e-52 177.0 16.6 1.6 2 0 0 2 2 2 1 Microtubule-binding stalk of dynein motor AAA_lid_1 PF17857.1 OQR90221.1 - 3.7e-18 65.6 0.2 2.8e-17 62.8 0.0 2.7 2 0 0 2 2 2 1 AAA+ lid domain AAA_7 PF12775.7 OQR90221.1 - 0.0004 19.9 0.3 0.001 18.6 0.1 1.9 2 0 0 2 2 2 1 P-loop containing dynein motor region Laminin_II PF06009.12 OQR90221.1 - 0.0099 15.9 4.4 0.0099 15.9 4.4 3.7 3 2 2 5 5 5 1 Laminin Domain II AAA_5 PF07728.14 OQR90221.1 - 0.013 15.5 0.1 1.4 8.9 0.0 3.5 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) PRO8NT PF08082.11 OQR90221.1 - 0.045 13.7 0.0 1.1 9.1 0.0 2.5 2 0 0 2 2 2 0 PRO8NT (NUC069), PrP8 N-terminal domain Fez1 PF06818.15 OQR90221.1 - 1.5 9.2 23.8 0.14 12.6 3.3 3.0 3 0 0 3 3 3 0 Fez1 V_ATPase_I PF01496.19 OQR90221.1 - 5.1 4.9 12.5 0.32 8.9 2.2 2.2 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family Pkinase PF00069.25 OQR90222.1 - 1.5e-78 263.8 0.0 1.9e-78 263.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQR90222.1 - 1.5e-33 116.2 0.0 1.9e-33 115.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OQR90222.1 - 3.3e-05 22.9 0.0 5.8e-05 22.0 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 OQR90222.1 - 0.00049 19.5 0.1 0.00075 18.9 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 OQR90222.1 - 0.0044 16.4 0.0 0.0083 15.5 0.0 1.5 1 1 0 1 1 1 1 Kinase-like PACT_coil_coil PF10495.9 OQR90222.1 - 0.14 12.8 0.1 0.26 11.9 0.1 1.4 1 0 0 1 1 1 0 Pericentrin-AKAP-450 domain of centrosomal targeting protein YscO PF07321.12 OQR90228.1 - 0.23 11.4 0.1 0.23 11.4 0.1 1.7 2 0 0 2 2 2 0 Type III secretion protein YscO PIGA PF08288.12 OQR90230.1 - 4.7e-39 132.9 0.4 1.2e-38 131.6 0.4 1.7 1 0 0 1 1 1 1 PIGA (GPI anchor biosynthesis) Glyco_transf_4 PF13439.6 OQR90230.1 - 2.6e-26 92.6 0.1 4.2e-26 92.0 0.1 1.3 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glycos_transf_1 PF00534.20 OQR90230.1 - 1.5e-24 86.4 0.0 2.5e-24 85.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 OQR90230.1 - 7.7e-22 78.2 0.0 1.4e-21 77.3 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 OQR90230.1 - 3.5e-10 40.6 0.0 6.1e-10 39.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.6 OQR90230.1 - 4.1e-05 23.9 0.0 0.00011 22.5 0.0 1.7 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_4_2 PF13477.6 OQR90230.1 - 0.00015 21.8 0.2 0.00027 21.0 0.2 1.4 1 0 0 1 1 1 1 Glycosyl transferase 4-like AD PF09793.9 OQR90231.1 - 1.6e-23 82.7 0.2 2.1e-23 82.3 0.2 1.2 1 0 0 1 1 1 1 Anticodon-binding domain Gemin6 PF06372.12 OQR90231.1 - 1.1e-06 28.3 0.0 0.0018 17.9 0.0 2.2 2 1 0 2 2 2 2 Gemin6 protein Cons_hypoth95 PF03602.15 OQR90231.1 - 0.062 12.9 0.0 0.089 12.4 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical protein 95 AtuA PF07287.11 OQR90231.1 - 0.089 11.5 0.0 0.13 10.9 0.0 1.2 1 0 0 1 1 1 0 Acyclic terpene utilisation family protein AtuA Glyco_hydro_12 PF01670.16 OQR90232.1 - 3.3e-46 158.0 6.0 3.9e-46 157.8 6.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 12 Acetyltransf_1 PF00583.25 OQR90245.1 - 3.1e-16 59.7 0.2 4.3e-16 59.2 0.2 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 OQR90245.1 - 1.1e-09 38.6 0.1 1.6e-09 38.0 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 OQR90245.1 - 1.7e-09 37.7 0.3 2.1e-09 37.4 0.3 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 OQR90245.1 - 3.3e-07 30.2 0.1 6.3e-07 29.3 0.1 1.5 1 1 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 OQR90245.1 - 0.00062 19.8 0.2 0.0012 18.9 0.2 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 OQR90245.1 - 0.0018 19.0 0.1 0.0025 18.5 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_13 PF13880.6 OQR90245.1 - 0.0044 17.0 0.1 0.0076 16.2 0.1 1.4 1 0 0 1 1 1 1 ESCO1/2 acetyl-transferase Ank_2 PF12796.7 OQR90246.1 - 1.8e-11 44.5 0.9 1.2e-06 29.0 0.1 2.9 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQR90246.1 - 1.9e-07 31.5 0.5 0.099 13.3 0.1 4.5 3 1 2 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQR90246.1 - 4e-07 29.8 1.4 7.8 7.4 0.0 5.8 6 1 1 7 7 7 2 Ankyrin repeat Ank_5 PF13857.6 OQR90246.1 - 8.3e-05 22.8 1.5 5.1 7.5 0.0 5.2 3 2 3 6 6 6 1 Ankyrin repeats (many copies) DUF5049 PF16468.5 OQR90246.1 - 0.027 14.4 0.0 0.65 9.9 0.0 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF5049) zf-UBR PF02207.20 OQR90247.1 - 1.2e-18 67.0 11.5 1.2e-18 67.0 11.5 2.8 2 0 0 2 2 2 1 Putative zinc finger in N-recognin (UBR box) ClpS PF02617.17 OQR90247.1 - 0.15 11.8 0.3 0.8 9.5 0.1 2.4 2 0 0 2 2 2 0 ATP-dependent Clp protease adaptor protein ClpS Metallophos PF00149.28 OQR90250.1 - 8.2e-06 26.5 0.1 1.2e-05 25.9 0.1 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase COX15-CtaA PF02628.15 OQR90251.1 - 2.7e-103 345.4 4.6 2.7e-103 345.4 4.6 1.7 2 0 0 2 2 2 1 Cytochrome oxidase assembly protein Ank_2 PF12796.7 OQR90251.1 - 3.8e-83 274.1 33.5 2.6e-09 37.6 0.1 14.7 10 4 5 15 15 14 13 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQR90251.1 - 1.7e-67 223.0 46.9 4e-06 27.3 0.1 20.7 15 6 6 21 21 21 18 Ankyrin repeats (many copies) Ank_5 PF13857.6 OQR90251.1 - 1.2e-61 203.9 40.0 4.1e-08 33.3 0.0 20.2 14 4 8 22 22 22 15 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQR90251.1 - 1.5e-38 126.4 33.7 0.0032 17.8 0.0 25.0 29 0 0 29 29 27 7 Ankyrin repeat Ank PF00023.30 OQR90251.1 - 7.9e-21 73.5 35.1 0.00092 19.6 0.1 15.9 19 2 1 20 20 18 5 Ankyrin repeat Ion_trans PF00520.31 OQR90251.1 - 1.2e-11 44.3 22.0 2.4e-11 43.3 22.0 1.5 1 0 0 1 1 1 1 Ion transport protein SMP_2 PF10144.9 OQR90251.1 - 0.0048 16.6 5.5 0.31 10.7 0.1 3.4 2 1 1 3 3 3 1 Bacterial virulence factor haemolysin DUF249 PF03158.13 OQR90251.1 - 0.032 14.0 4.2 8 6.1 0.0 5.7 4 1 3 7 7 7 0 Multigene family 530 protein Nipped-B_C PF12830.7 OQR90251.1 - 0.048 13.6 0.7 0.14 12.1 0.7 1.8 1 0 0 1 1 1 0 Sister chromatid cohesion C-terminus DIRP PF06584.13 OQR90251.1 - 0.96 9.7 2.8 3 8.1 2.8 1.8 1 0 0 1 1 1 0 DIRP AAA_2 PF07724.14 OQR90264.1 - 3.1e-45 154.3 0.0 5.2e-45 153.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA PF00004.29 OQR90264.1 - 1.1e-14 55.0 0.0 2.2e-14 54.0 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.9 OQR90264.1 - 9.5e-11 41.6 0.0 2.2e-10 40.4 0.0 1.6 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA_22 PF13401.6 OQR90264.1 - 1.4e-05 25.3 0.2 0.00015 22.1 0.2 2.3 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.12 OQR90264.1 - 0.0002 21.2 0.1 0.0029 17.4 0.1 2.4 2 1 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 OQR90264.1 - 0.00029 20.9 0.2 0.0018 18.3 0.2 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) MCM PF00493.23 OQR90264.1 - 0.00038 19.6 0.7 0.0016 17.5 0.2 2.0 2 0 0 2 2 2 1 MCM P-loop domain Sigma54_activat PF00158.26 OQR90264.1 - 0.001 18.8 0.1 0.014 15.1 0.1 2.2 1 1 0 1 1 1 1 Sigma-54 interaction domain Sigma54_activ_2 PF14532.6 OQR90264.1 - 0.0011 19.1 0.0 0.0035 17.4 0.0 1.9 1 1 0 1 1 1 1 Sigma-54 interaction domain Mg_chelatase PF01078.21 OQR90264.1 - 0.0012 18.3 0.1 0.017 14.5 0.0 2.4 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_7 PF12775.7 OQR90264.1 - 0.0027 17.3 0.0 0.0052 16.3 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region T2SSE PF00437.20 OQR90264.1 - 0.0027 16.8 0.0 0.0048 16.0 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein IstB_IS21 PF01695.17 OQR90264.1 - 0.0085 15.8 0.0 0.019 14.7 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_16 PF13191.6 OQR90264.1 - 0.012 16.0 0.1 0.045 14.1 0.1 1.8 1 1 1 2 2 2 0 AAA ATPase domain AAA_18 PF13238.6 OQR90264.1 - 0.013 16.1 0.0 0.025 15.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 OQR90264.1 - 0.021 15.0 0.0 0.057 13.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.18 OQR90264.1 - 0.022 14.1 0.1 0.049 13.0 0.1 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_24 PF13479.6 OQR90264.1 - 0.027 14.2 0.0 0.045 13.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain IPT PF01745.16 OQR90264.1 - 0.038 13.4 0.2 0.092 12.1 0.2 1.5 1 0 0 1 1 1 0 Isopentenyl transferase AAA_14 PF13173.6 OQR90264.1 - 0.038 14.0 0.0 0.085 12.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain zinc_ribbon_5 PF13719.6 OQR90264.1 - 0.048 13.4 1.1 11 5.9 0.1 2.5 2 0 0 2 2 2 0 zinc-ribbon domain ResIII PF04851.15 OQR90264.1 - 0.048 13.7 0.0 0.09 12.8 0.0 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit TrwB_AAD_bind PF10412.9 OQR90264.1 - 0.049 12.5 0.0 0.11 11.4 0.0 1.5 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain ABC_tran PF00005.27 OQR90264.1 - 0.057 13.9 0.0 0.16 12.5 0.0 1.8 1 0 0 1 1 1 0 ABC transporter PhoH PF02562.16 OQR90264.1 - 0.061 12.8 0.0 0.13 11.7 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein DEAD PF00270.29 OQR90264.1 - 0.1 12.3 0.3 0.42 10.4 0.2 2.0 1 1 0 2 2 2 0 DEAD/DEAH box helicase NACHT PF05729.12 OQR90264.1 - 0.12 12.3 0.1 0.55 10.1 0.0 2.2 2 0 0 2 2 2 0 NACHT domain zinc_ribbon_2 PF13240.6 OQR90264.1 - 0.12 12.1 0.1 0.29 10.9 0.1 1.6 1 0 0 1 1 1 0 zinc-ribbon domain DZR PF12773.7 OQR90264.1 - 0.21 11.7 0.9 0.4 10.7 0.9 1.4 1 0 0 1 1 1 0 Double zinc ribbon GLE1 PF07817.13 OQR90265.1 - 7.9e-50 169.4 0.1 7.9e-50 169.4 0.1 1.7 2 0 0 2 2 2 1 GLE1-like protein PhyH PF05721.13 OQR90265.1 - 0.85 9.8 4.4 1.9 8.7 4.4 1.5 1 0 0 1 1 1 0 Phytanoyl-CoA dioxygenase (PhyH) DDHD PF02862.17 OQR90265.1 - 2.8 8.1 6.8 2.9 8.0 4.3 2.2 2 0 0 2 2 2 0 DDHD domain V_ATPase_I PF01496.19 OQR90265.1 - 5.4 4.8 8.3 7.4 4.3 8.3 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Rx_N PF18052.1 OQR90265.1 - 6.9 7.0 11.2 5.1 7.5 9.0 2.0 2 0 0 2 2 2 0 Rx N-terminal domain SAPS PF04499.15 OQR90265.1 - 8.6 5.0 12.3 17 4.0 12.3 1.4 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein UPF0016 PF01169.19 OQR90266.1 - 2e-43 146.6 24.5 1.3e-21 76.7 7.0 2.2 2 0 0 2 2 2 2 Uncharacterized protein family UPF0016 Mntp PF02659.15 OQR90266.1 - 0.00022 21.0 5.2 0.0036 17.1 0.0 2.7 2 0 0 2 2 2 1 Putative manganese efflux pump EF-hand_1 PF00036.32 OQR90266.1 - 0.0013 18.2 0.1 0.0036 16.8 0.1 1.8 1 0 0 1 1 1 1 EF hand EF-hand_5 PF13202.6 OQR90266.1 - 0.0031 16.9 0.2 0.0071 15.8 0.2 1.6 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 OQR90266.1 - 0.0033 17.2 0.1 0.011 15.6 0.1 1.8 1 0 0 1 1 1 1 EF-hand domain TerC PF03741.16 OQR90266.1 - 0.0075 16.0 1.3 0.0075 16.0 1.3 2.4 2 1 1 3 3 3 2 Integral membrane protein TerC family EF-hand_7 PF13499.6 OQR90266.1 - 0.079 13.4 0.0 0.15 12.5 0.0 1.4 1 0 0 1 1 1 0 EF-hand domain pair EF-hand_7 PF13499.6 OQR90270.1 - 2.3e-21 76.0 9.5 1.4e-10 41.4 0.7 2.5 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 OQR90270.1 - 2.1e-16 58.4 9.8 1.2e-07 31.1 1.1 3.8 4 0 0 4 4 4 3 EF-hand domain EF-hand_1 PF00036.32 OQR90270.1 - 1.9e-15 55.2 6.2 8.4e-06 25.0 0.1 3.8 4 0 0 4 4 4 3 EF hand EF-hand_5 PF13202.6 OQR90270.1 - 1.5e-06 27.4 8.7 0.0026 17.2 0.3 3.2 4 0 0 4 4 4 2 EF hand EF-hand_9 PF14658.6 OQR90270.1 - 6.8e-05 23.1 0.2 0.0021 18.3 0.2 2.5 2 1 1 3 3 3 1 EF-hand domain EF-hand_8 PF13833.6 OQR90270.1 - 0.00025 20.8 7.1 0.021 14.6 0.4 3.3 2 2 2 4 4 4 3 EF-hand domain pair Caleosin PF05042.13 OQR90270.1 - 0.0043 17.0 0.3 1.9 8.4 0.0 2.4 2 0 0 2 2 2 2 Caleosin related protein Dockerin_1 PF00404.18 OQR90270.1 - 0.019 15.1 0.0 2.3 8.5 0.0 3.1 3 0 0 3 3 3 0 Dockerin type I domain PWWP PF00855.17 OQR90275.1 - 6.6e-11 42.5 0.0 6.6e-11 42.5 0.0 4.6 2 1 0 2 2 2 1 PWWP domain Med26 PF08711.11 OQR90275.1 - 3.3e-05 23.8 0.1 0.00017 21.5 0.1 2.3 1 0 0 1 1 1 1 TFIIS helical bundle-like domain JAB PF01398.21 OQR90275.1 - 1.6 8.7 0.0 1.6 8.7 0.0 3.4 4 1 0 4 4 4 0 JAB1/Mov34/MPN/PAD-1 ubiquitin protease RicinB_lectin_2 PF14200.6 OQR90276.1 - 9.1e-05 23.1 7.0 0.62 10.8 0.2 3.9 1 1 3 5 5 5 4 Ricin-type beta-trefoil lectin domain-like FRG1 PF06229.12 OQR90276.1 - 0.0096 15.7 0.0 11 5.6 0.0 4.0 3 2 1 4 4 4 1 FRG1-like domain Integrase_H2C2 PF17921.1 OQR90276.1 - 0.027 14.6 1.2 93 3.2 0.0 4.6 6 0 0 6 6 6 0 Integrase zinc binding domain PAP2 PF01569.21 OQR90283.1 - 1.9e-18 66.5 4.9 1.9e-18 66.5 4.9 2.3 2 1 0 2 2 2 1 PAP2 superfamily PDCD2_C PF04194.13 OQR90284.1 - 3.4e-40 138.0 5.4 2.1e-38 132.1 0.7 3.5 3 1 0 3 3 3 2 Programmed cell death protein 2, C-terminal putative domain zf-MYND PF01753.18 OQR90284.1 - 3.7e-07 30.1 11.5 3.7e-07 30.1 11.5 2.2 3 0 0 3 3 3 1 MYND finger zf-HIT PF04438.16 OQR90284.1 - 0.0054 16.6 4.1 0.0054 16.6 4.1 3.5 4 0 0 4 4 4 1 HIT zinc finger HTH_Crp_2 PF13545.6 OQR90284.1 - 0.13 12.3 0.0 0.37 10.8 0.0 1.8 1 1 0 1 1 1 0 Crp-like helix-turn-helix domain DUSP PF06337.12 OQR90285.1 - 2e-08 34.7 0.0 3.8e-08 33.8 0.0 1.5 1 0 0 1 1 1 1 DUSP domain Cwf_Cwc_15 PF04889.12 OQR90285.1 - 0.068 12.9 10.2 0.32 10.7 7.0 2.1 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein AP3D1 PF06375.11 OQR90285.1 - 2 8.6 14.6 0.39 11.0 10.8 1.7 2 0 0 2 2 2 0 AP-3 complex subunit delta-1 Trypan_PARP PF05887.11 OQR90285.1 - 8.1 6.4 8.7 1.8 8.6 2.7 2.1 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) DDOST_48kD PF03345.14 OQR90286.1 - 1e-113 380.3 0.0 1.5e-113 379.8 0.0 1.2 1 0 0 1 1 1 1 Oligosaccharyltransferase 48 kDa subunit beta Pkinase PF00069.25 OQR90286.1 - 1.6e-16 60.4 0.0 3.2e-16 59.5 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQR90286.1 - 1.2e-12 47.7 0.0 2.4e-12 46.7 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 OQR90286.1 - 0.1 12.5 0.0 0.19 11.6 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Beach PF02138.18 OQR90292.1 - 1.5e-120 401.7 0.1 3.6e-120 400.5 0.0 1.7 2 0 0 2 2 2 1 Beige/BEACH domain WD40 PF00400.32 OQR90292.1 - 6.6e-08 33.1 9.6 0.004 18.0 0.1 5.5 4 1 0 4 4 4 2 WD domain, G-beta repeat PH_BEACH PF14844.6 OQR90292.1 - 8.3e-05 22.6 0.1 0.00024 21.1 0.1 1.8 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH Laminin_G_3 PF13385.6 OQR90292.1 - 0.012 15.8 0.0 0.043 14.0 0.0 1.9 1 0 0 1 1 1 0 Concanavalin A-like lectin/glucanases superfamily Ge1_WD40 PF16529.5 OQR90292.1 - 0.019 13.9 0.0 0.042 12.8 0.0 1.5 1 0 0 1 1 1 0 WD40 region of Ge1, enhancer of mRNA-decapping protein AAA_16 PF13191.6 OQR90292.1 - 0.16 12.4 0.1 0.45 10.9 0.1 1.8 1 0 0 1 1 1 0 AAA ATPase domain DUF3506 PF12014.8 OQR90292.1 - 0.2 11.7 0.0 1.1 9.2 0.0 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF3506) TetR_C_32 PF09209.11 OQR90296.1 - 0.085 12.9 0.0 13 5.8 0.0 2.5 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain Sec_GG PF07549.14 OQR90296.1 - 0.11 12.0 0.9 0.37 10.4 0.9 2.0 1 0 0 1 1 1 0 SecD/SecF GG Motif MtmB PF05369.12 OQR90297.1 - 0.083 11.7 0.0 0.11 11.2 0.0 1.2 1 0 0 1 1 1 0 Monomethylamine methyltransferase MtmB Pkinase_Tyr PF07714.17 OQR90308.1 - 0.0017 17.7 0.0 0.0029 17.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase DUF2614 PF11023.8 OQR90308.1 - 0.011 15.8 0.3 0.023 14.8 0.3 1.5 1 0 0 1 1 1 0 Zinc-ribbon containing domain DZR PF12773.7 OQR90308.1 - 0.018 15.0 2.1 0.018 15.0 2.1 2.1 2 0 0 2 2 2 0 Double zinc ribbon zf-ribbon_3 PF13248.6 OQR90308.1 - 0.068 12.6 2.5 0.22 11.0 2.5 2.0 1 0 0 1 1 1 0 zinc-ribbon domain Pkinase PF00069.25 OQR90308.1 - 0.12 11.7 0.0 0.18 11.1 0.0 1.4 1 1 0 1 1 1 0 Protein kinase domain Pkinase_Tyr PF07714.17 OQR90309.1 - 8.3e-09 35.1 0.0 1e-08 34.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OQR90309.1 - 5.8e-07 29.1 0.0 6.4e-07 29.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain PRORP PF16953.5 OQR90317.1 - 2.8e-42 144.9 0.2 5.5e-42 143.9 0.2 1.4 1 0 0 1 1 1 1 Protein-only RNase P PPR_long PF17177.4 OQR90317.1 - 5.9e-42 143.4 0.9 5.9e-42 143.4 0.9 1.6 2 0 0 2 2 2 1 Pentacotripeptide-repeat region of PRORP PPR PF01535.20 OQR90317.1 - 1.4e-08 34.5 0.1 0.088 13.1 0.0 4.6 4 0 0 4 4 4 3 PPR repeat PPR_3 PF13812.6 OQR90317.1 - 3.7e-08 33.3 2.2 0.17 12.0 0.1 4.2 4 0 0 4 4 4 3 Pentatricopeptide repeat domain PPR_2 PF13041.6 OQR90317.1 - 1.6e-06 28.2 0.1 0.84 9.9 0.1 4.4 3 1 1 4 4 4 2 PPR repeat family RNase_Zc3h12a PF11977.8 OQR90317.1 - 6e-05 22.9 0.6 0.00019 21.2 0.1 2.1 2 1 0 2 2 2 1 Zc3h12a-like Ribonuclease NYN domain Phage_ABA_S PF18066.1 OQR90317.1 - 0.036 14.7 2.4 1.6 9.4 0.1 3.8 2 1 2 4 4 4 0 Phage ABA sandwich domain Meiosis_expr PF15163.6 OQR90317.1 - 0.076 13.7 1.6 1.2 9.9 0.1 2.7 2 0 0 2 2 2 0 Meiosis-expressed PPR_1 PF12854.7 OQR90317.1 - 0.59 9.9 2.1 9.4 6.0 0.1 3.5 5 0 0 5 5 5 0 PPR repeat FYVE PF01363.21 OQR90321.1 - 1.5e-15 57.1 11.2 3.8e-15 55.8 11.2 1.7 1 0 0 1 1 1 1 FYVE zinc finger LRR_6 PF13516.6 OQR90321.1 - 8.6e-07 28.5 7.6 0.47 10.6 0.0 4.9 5 0 0 5 5 5 3 Leucine Rich repeat GAF PF01590.26 OQR90321.1 - 1.3e-06 29.1 0.0 3.4e-06 27.7 0.0 1.8 1 0 0 1 1 1 1 GAF domain IQ PF00612.27 OQR90321.1 - 0.0021 17.7 25.1 0.55 10.2 0.0 6.8 6 0 0 6 6 6 3 IQ calmodulin-binding motif FYVE_2 PF02318.16 OQR90321.1 - 0.042 14.1 9.0 0.29 11.4 9.0 2.5 1 0 0 1 1 1 0 FYVE-type zinc finger Lactamase_B_2 PF12706.7 OQR90323.1 - 6.3e-20 71.5 0.0 7.9e-19 68.0 0.1 2.1 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B_4 PF13691.6 OQR90323.1 - 1.4e-08 34.2 0.0 4.8e-08 32.6 0.0 1.9 1 0 0 1 1 1 1 tRNase Z endonuclease Lactamase_B PF00753.27 OQR90323.1 - 0.007 16.4 0.0 0.029 14.4 0.0 1.9 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Spt5_N PF11942.8 OQR90323.1 - 6.3 7.8 7.8 10 7.2 4.3 2.3 1 1 1 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal Gp_dh_C PF02800.20 OQR90324.1 - 1.8e-41 141.4 0.1 2.5e-41 140.9 0.1 1.2 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 OQR90324.1 - 1.4e-38 131.3 0.0 2.5e-38 130.5 0.0 1.4 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DapB_N PF01113.20 OQR90324.1 - 0.078 13.1 0.0 0.19 11.9 0.0 1.8 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Sulfate_transp PF00916.20 OQR90325.1 - 3.4e-80 269.6 25.2 2.8e-79 266.6 25.2 2.0 1 1 0 1 1 1 1 Sulfate permease family STAS PF01740.21 OQR90325.1 - 7.9e-13 48.1 0.0 1.4e-12 47.2 0.0 1.4 1 0 0 1 1 1 1 STAS domain WD40 PF00400.32 OQR90361.1 - 2.9e-12 46.9 20.7 0.27 12.2 0.0 9.7 11 0 0 11 11 11 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OQR90361.1 - 2.4e-06 27.8 1.2 1.2 9.5 0.1 5.3 4 2 1 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain EF-hand_8 PF13833.6 OQR90361.1 - 1.5e-05 24.8 0.0 5.3e-05 23.0 0.0 2.0 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_7 PF13499.6 OQR90361.1 - 7.4e-05 23.1 0.1 0.0002 21.8 0.1 1.8 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.6 OQR90361.1 - 0.00011 21.6 0.3 0.00025 20.4 0.3 1.6 1 0 0 1 1 1 1 EF hand EF-hand_1 PF00036.32 OQR90361.1 - 0.00019 20.7 0.5 0.00054 19.3 0.5 1.8 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 OQR90361.1 - 0.002 17.9 0.2 0.0073 16.2 0.2 2.0 1 0 0 1 1 1 1 EF-hand domain Nup160 PF11715.8 OQR90361.1 - 0.004 15.9 0.9 0.016 13.9 0.1 1.9 1 1 0 2 2 2 1 Nucleoporin Nup120/160 RNase_T PF00929.24 OQR90362.1 - 1.3e-16 61.6 0.0 2.2e-16 60.9 0.0 1.4 1 0 0 1 1 1 1 Exonuclease DNA_pol_A_exo1 PF01612.20 OQR90362.1 - 9.1e-05 22.2 0.9 0.0002 21.1 0.1 2.0 2 1 0 2 2 2 1 3'-5' exonuclease MFS_2 PF13347.6 OQR90363.1 - 2.5e-08 32.9 11.2 2.5e-08 32.9 11.2 2.7 2 1 0 2 2 2 2 MFS/sugar transport protein MGC-24 PF05283.11 OQR90365.1 - 0.044 14.2 18.8 0.064 13.7 18.8 1.3 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin PHM7_cyt PF14703.6 OQR90366.1 - 6.7e-08 33.0 2.4 5.1e-07 30.1 1.5 2.5 2 1 0 2 2 2 1 Cytosolic domain of 10TM putative phosphate transporter RSN1_7TM PF02714.15 OQR90366.1 - 2.9e-05 23.5 6.7 2.9e-05 23.5 6.7 2.5 2 1 0 2 2 2 1 Calcium-dependent channel, 7TM region, putative phosphate DUF4349 PF14257.6 OQR90366.1 - 0.03 13.8 1.9 0.074 12.5 1.9 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) APG17 PF04108.12 OQR90366.1 - 0.074 12.2 1.9 0.085 12.0 0.8 1.5 2 0 0 2 2 2 0 Autophagy protein Apg17 FapA PF03961.13 OQR90366.1 - 0.11 11.1 0.6 0.17 10.5 0.6 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A HemX PF04375.14 OQR90366.1 - 0.12 11.7 1.0 0.21 10.8 1.0 1.3 1 0 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase Anoctamin PF04547.12 OQR90366.1 - 0.35 9.7 10.7 0.19 10.5 0.1 3.3 4 0 0 4 4 4 0 Calcium-activated chloride channel Uso1_p115_C PF04871.13 OQR90366.1 - 0.67 10.3 5.8 1.3 9.4 5.8 1.4 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region Lipase_3 PF01764.25 OQR90367.1 - 3e-26 92.0 0.0 5.6e-26 91.1 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) DUF2974 PF11187.8 OQR90367.1 - 0.0025 17.4 0.0 0.02 14.4 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF2974) DUF2924 PF11149.8 OQR90368.1 - 0.26 11.7 2.8 0.5 10.8 0.0 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2924) NPV_P10 PF05531.12 OQR90368.1 - 3.7 8.1 5.9 2.7 8.5 0.6 2.9 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein tRNA-synt_1g PF09334.11 OQR90369.1 - 1.2e-100 337.0 1.5 8.5e-55 186.1 0.0 2.1 1 1 1 2 2 2 2 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 OQR90369.1 - 7.9e-37 126.8 4.5 8.6e-22 77.1 0.1 3.2 1 1 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA_bind PF01588.20 OQR90369.1 - 1.4e-24 86.0 0.0 2.4e-24 85.2 0.0 1.4 1 0 0 1 1 1 1 Putative tRNA binding domain tRNA-synt_1e PF01406.19 OQR90369.1 - 5.3e-13 49.0 0.6 8.4e-08 31.9 0.7 2.2 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain tRNA-synt_1f PF01921.18 OQR90369.1 - 1.8e-06 27.1 0.3 0.035 13.0 0.0 3.0 3 0 0 3 3 3 2 tRNA synthetases class I (K) Anticodon_1 PF08264.13 OQR90369.1 - 0.015 15.3 0.0 0.034 14.1 0.0 1.6 1 0 0 1 1 1 0 Anticodon-binding domain of tRNA Peptidase_S8 PF00082.22 OQR90387.1 - 4.5e-36 124.6 2.6 8e-36 123.8 2.6 1.5 1 0 0 1 1 1 1 Subtilase family Ank_2 PF12796.7 OQR90402.1 - 2.1e-66 220.5 11.8 2.5e-13 50.4 0.2 5.5 2 2 2 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQR90402.1 - 1.8e-59 197.4 16.3 1e-09 38.8 0.1 8.6 2 2 8 10 10 10 10 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQR90402.1 - 4e-48 155.8 6.1 0.0014 18.9 0.1 12.6 12 0 0 12 12 12 12 Ankyrin repeat Ank PF00023.30 OQR90402.1 - 1.2e-36 123.6 26.7 4.4e-05 23.7 0.4 12.8 14 0 0 14 14 14 8 Ankyrin repeat Ank_5 PF13857.6 OQR90402.1 - 1.5e-34 117.5 17.7 1.6e-05 25.1 0.1 10.8 2 2 10 12 12 12 10 Ankyrin repeats (many copies) Pkinase_Tyr PF07714.17 OQR90402.1 - 6.4e-16 58.4 0.0 1.1e-15 57.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OQR90402.1 - 8.9e-14 51.5 0.1 1.5e-13 50.7 0.1 1.3 1 0 0 1 1 1 1 Protein kinase domain cobW PF02492.19 OQR90408.1 - 4.6e-47 159.9 0.8 6.6e-47 159.4 0.8 1.2 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.14 OQR90408.1 - 1e-10 41.4 0.1 3.2e-10 39.8 0.1 1.9 1 0 0 1 1 1 1 Cobalamin synthesis protein cobW C-terminal domain RsgA_GTPase PF03193.16 OQR90408.1 - 0.019 14.9 0.0 0.74 9.7 0.0 2.3 2 0 0 2 2 2 0 RsgA GTPase MobB PF03205.14 OQR90408.1 - 0.061 13.2 0.0 0.14 12.1 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B SRPRB PF09439.10 OQR90408.1 - 0.16 11.4 0.0 0.36 10.2 0.0 1.5 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Peptidase_M24 PF00557.24 OQR90409.1 - 1e-50 172.3 0.1 1.3e-50 172.0 0.1 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 zf-C6H2 PF15801.5 OQR90409.1 - 4.3e-17 62.1 6.4 7.5e-17 61.4 6.4 1.4 1 0 0 1 1 1 1 zf-MYND-like zinc finger, mRNA-binding zf-MYND PF01753.18 OQR90409.1 - 0.00038 20.5 4.3 0.0009 19.3 4.3 1.6 1 0 0 1 1 1 1 MYND finger zf-HIT PF04438.16 OQR90409.1 - 0.0033 17.2 3.9 0.0065 16.3 3.9 1.5 1 0 0 1 1 1 1 HIT zinc finger p450 PF00067.22 OQR90410.1 - 2.9e-46 158.2 0.2 3.2e-46 158.0 0.2 1.0 1 0 0 1 1 1 1 Cytochrome P450 WD40 PF00400.32 OQR90411.1 - 7.9e-51 168.9 58.2 0.0077 17.1 0.0 25.5 26 1 1 27 27 27 15 WD domain, G-beta repeat HELP PF03451.14 OQR90411.1 - 2.4e-33 113.8 0.8 1.6e-18 66.3 0.1 4.3 5 0 0 5 5 5 3 HELP motif ANAPC4_WD40 PF12894.7 OQR90411.1 - 9.3e-25 86.8 2.0 0.003 17.8 0.0 12.9 8 3 5 13 13 13 4 Anaphase-promoting complex subunit 4 WD40 domain EF-hand_7 PF13499.6 OQR90411.1 - 1.3e-07 31.9 0.0 9.4e-05 22.8 0.0 2.6 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 OQR90411.1 - 5.9e-06 25.8 0.1 2.8 8.1 0.0 4.2 4 0 0 4 4 4 2 EF-hand domain CPSF_A PF03178.15 OQR90411.1 - 1.4e-05 24.6 0.0 0.56 9.5 0.0 4.6 4 0 0 4 4 4 1 CPSF A subunit region Ge1_WD40 PF16529.5 OQR90411.1 - 3.4e-05 23.0 2.5 0.077 11.9 0.0 5.4 5 0 0 5 5 5 1 WD40 region of Ge1, enhancer of mRNA-decapping protein EF-hand_1 PF00036.32 OQR90411.1 - 0.00074 18.9 0.1 0.74 9.5 0.0 3.6 3 0 0 3 3 3 1 EF hand Coatomer_WDAD PF04053.14 OQR90411.1 - 0.014 14.4 0.7 7.8 5.4 0.0 4.0 4 1 0 5 5 5 0 Coatomer WD associated region Sensor PF13796.6 OQR90417.1 - 3.1e-09 37.1 2.1 3.5e-09 36.9 1.0 1.6 1 1 1 2 2 2 2 Putative sensor eIF-6 PF01912.18 OQR90420.1 - 3.7e-32 111.3 1.6 5.7e-32 110.7 0.8 1.6 2 0 0 2 2 2 1 eIF-6 family DUF1676 PF07898.13 OQR90423.1 - 0.02 14.9 0.9 0.037 14.1 0.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1676) UCH PF00443.29 OQR90424.1 - 3e-52 177.7 0.2 5.8e-52 176.7 0.2 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 OQR90424.1 - 3e-24 86.2 1.4 3.9e-24 85.8 0.1 1.8 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase RNA_pol_3_Rpc31 PF11705.8 OQR90424.1 - 0.00029 21.2 0.0 0.00029 21.2 0.0 3.6 4 0 0 4 4 4 2 DNA-directed RNA polymerase III subunit Rpc31 DUF1464 PF07318.12 OQR90424.1 - 0.043 13.0 0.0 0.078 12.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1464) zf-MYND PF01753.18 OQR90425.1 - 2.9e-09 36.8 17.5 5.3e-09 36.0 17.5 1.4 1 0 0 1 1 1 1 MYND finger UCH PF00443.29 OQR90426.1 - 1.1e-60 205.4 0.7 1.1e-60 205.4 0.7 1.9 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 OQR90426.1 - 6.8e-19 68.6 0.8 1.3e-18 67.7 0.8 1.7 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Rsa3 PF14615.6 OQR90426.1 - 0.0032 17.0 0.9 1.9 8.2 0.1 2.8 2 0 0 2 2 2 2 Ribosome-assembly protein 3 Ion_trans PF00520.31 OQR90426.1 - 0.0038 16.5 4.9 0.0064 15.8 4.9 1.2 1 0 0 1 1 1 1 Ion transport protein Atg14 PF10186.9 OQR90426.1 - 0.073 12.1 3.9 0.3 10.1 4.0 1.9 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 BST2 PF16716.5 OQR90426.1 - 0.62 10.7 4.9 2.2 8.9 4.9 1.9 1 0 0 1 1 1 0 Bone marrow stromal antigen 2 DUF2570 PF10828.8 OQR90426.1 - 3.6 7.4 9.3 2.7 7.9 6.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2570) RicinB_lectin_2 PF14200.6 OQR90428.1 - 0.12 13.1 2.3 0.12 13.2 1.0 1.7 1 1 1 2 2 2 0 Ricin-type beta-trefoil lectin domain-like CID_GANP PF16766.5 OQR90428.1 - 0.21 11.8 0.0 4.5 7.6 0.0 2.1 2 0 0 2 2 2 0 Binding region of GANP to ENY2 HigB-like_toxin PF05015.13 OQR90429.1 - 0.082 13.3 0.1 2.3 8.7 0.2 3.3 2 0 0 2 2 2 0 RelE-like toxin of type II toxin-antitoxin system HigB GST_C_3 PF14497.6 OQR90430.1 - 5.6e-12 45.7 0.0 1.1e-11 44.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 OQR90430.1 - 1.8e-09 37.8 0.0 0.00063 20.0 0.0 2.6 2 0 0 2 2 2 2 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 OQR90430.1 - 0.00025 21.4 0.0 0.49 10.8 0.0 2.5 2 0 0 2 2 2 2 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 OQR90430.1 - 0.0027 17.7 0.0 0.0059 16.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 OQR90430.1 - 0.0028 17.9 0.0 0.012 15.9 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 OQR90431.1 - 1.4e-12 47.7 0.0 2.2e-12 47.0 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 OQR90431.1 - 5.7e-06 26.6 0.0 1.1e-05 25.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 OQR90431.1 - 0.0023 17.9 0.0 0.0055 16.7 0.0 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 OQR90431.1 - 0.012 16.0 0.0 0.025 15.0 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 OQR90431.1 - 0.014 15.6 0.0 0.021 15.0 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 OQR90431.1 - 0.016 15.5 0.0 0.031 14.6 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain PX PF00787.24 OQR90438.1 - 1.5e-08 34.6 0.0 1.8e-08 34.3 0.0 1.1 1 0 0 1 1 1 1 PX domain DDE_1 PF03184.19 OQR90439.1 - 4.7e-36 124.1 0.1 7.6e-36 123.4 0.1 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.16 OQR90439.1 - 7.3e-10 38.7 0.1 2.8e-09 36.9 0.1 2.1 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain HTH_ABP1_N PF18107.1 OQR90439.1 - 0.0014 18.3 0.1 0.0014 18.3 0.1 2.5 3 0 0 3 3 3 1 Fission yeast centromere protein N-terminal domain Evr1_Alr PF04777.13 OQR90439.1 - 0.016 15.6 1.1 3.7 8.1 0.0 3.2 3 0 0 3 3 3 0 Erv1 / Alr family Atg14 PF10186.9 OQR90440.1 - 0.16 11.0 19.7 0.22 10.6 4.8 2.7 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 UDPGT PF00201.18 OQR90441.1 - 1.2e-26 93.6 0.1 8.6e-26 90.8 0.1 2.0 1 1 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.16 OQR90441.1 - 3.9e-05 23.7 0.0 5.9e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Glyco_transf_28 PF03033.20 OQR90441.1 - 0.00081 19.4 0.0 0.0021 18.1 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain Glyco_trans_1_3 PF13528.6 OQR90441.1 - 0.006 15.9 0.0 0.36 10.0 0.0 2.2 2 0 0 2 2 2 2 Glycosyl transferase family 1 Pkinase PF00069.25 OQR90442.1 - 3e-68 230.0 0.0 4.1e-68 229.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQR90442.1 - 3e-39 134.9 0.0 4.1e-39 134.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OQR90442.1 - 3.4e-10 39.7 0.0 7.7e-06 25.4 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Pkinase_fungal PF17667.1 OQR90442.1 - 0.014 14.2 0.0 0.031 13.0 0.0 1.5 1 0 0 1 1 1 0 Fungal protein kinase Seadorna_VP7 PF07387.11 OQR90442.1 - 0.11 11.5 0.0 0.21 10.6 0.0 1.4 1 0 0 1 1 1 0 Seadornavirus VP7 Pkinase_Tyr PF07714.17 OQR90449.1 - 8.6e-62 208.7 0.0 2e-31 109.2 0.0 3.3 2 2 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 OQR90449.1 - 1.6e-58 198.2 0.0 3.9e-29 101.8 0.0 3.0 2 2 0 2 2 2 2 Protein kinase domain APH PF01636.23 OQR90449.1 - 6.2e-05 23.0 0.1 0.012 15.6 0.1 2.6 3 0 0 3 3 3 1 Phosphotransferase enzyme family Kdo PF06293.14 OQR90449.1 - 0.00079 18.8 0.6 0.063 12.6 0.1 2.2 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family DNA_pol_D_N PF18018.1 OQR90449.1 - 0.1 12.7 0.0 0.33 11.1 0.0 1.9 1 0 0 1 1 1 0 DNA polymerase delta subunit OB-fold domain DUF5365 PF17326.2 OQR90449.1 - 0.17 12.3 0.4 1.7 9.1 0.1 2.8 3 1 0 3 3 3 0 Family of unknown function (DUF5365) Brr6_like_C_C PF10104.9 OQR90449.1 - 0.35 10.7 1.3 3.8 7.3 0.1 2.2 2 0 0 2 2 2 0 Di-sulfide bridge nucleocytoplasmic transport domain NUDIX PF00293.28 OQR90450.1 - 7.4e-15 55.1 0.1 1.2e-14 54.5 0.1 1.4 1 0 0 1 1 1 1 NUDIX domain Glyco_hydro_17 PF00332.18 OQR90450.1 - 2.6e-05 24.0 6.2 0.0014 18.3 6.2 2.3 1 1 0 1 1 1 1 Glycosyl hydrolases family 17 Ricin_B_lectin PF00652.22 OQR90450.1 - 0.001 19.3 2.5 0.0015 18.8 0.7 2.2 2 1 0 2 2 2 1 Ricin-type beta-trefoil lectin domain AAA PF00004.29 OQR90451.1 - 1.3e-45 155.0 0.0 7.9e-41 139.6 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) Bromodomain PF00439.25 OQR90451.1 - 1.7e-20 72.9 0.2 4.7e-20 71.4 0.2 1.7 1 0 0 1 1 1 1 Bromodomain AAA_lid_3 PF17862.1 OQR90451.1 - 6.7e-10 38.6 0.0 2.5e-09 36.8 0.0 2.0 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 OQR90451.1 - 5e-07 30.3 0.0 2.1e-05 25.0 0.0 3.3 2 0 0 2 2 2 1 AAA ATPase domain AAA_2 PF07724.14 OQR90451.1 - 9.9e-07 29.0 0.0 4e-06 27.1 0.0 2.1 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 OQR90451.1 - 3.2e-06 27.5 0.0 0.076 13.3 0.1 4.3 3 1 0 3 3 3 1 AAA domain IstB_IS21 PF01695.17 OQR90451.1 - 2e-05 24.4 0.0 0.00014 21.7 0.0 2.4 3 0 0 3 3 2 1 IstB-like ATP binding protein AAA_5 PF07728.14 OQR90451.1 - 0.0014 18.6 0.1 0.011 15.7 0.0 2.7 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) T2SSC PF11356.8 OQR90451.1 - 0.0035 17.2 0.2 0.0099 15.8 0.2 1.7 1 0 0 1 1 1 1 Type II secretion system protein C PHD PF00628.29 OQR90451.1 - 0.0039 17.1 9.3 0.0049 16.7 7.8 2.0 2 0 0 2 2 2 1 PHD-finger Zf_RING PF16744.5 OQR90451.1 - 0.0043 17.1 4.0 0.012 15.7 4.0 1.8 1 0 0 1 1 1 1 KIAA1045 RING finger RNA_helicase PF00910.22 OQR90451.1 - 0.0045 17.4 0.0 0.033 14.6 0.0 2.5 2 0 0 2 2 2 1 RNA helicase AAA_14 PF13173.6 OQR90451.1 - 0.0056 16.7 0.0 0.11 12.5 0.0 2.7 2 0 0 2 2 2 1 AAA domain Sigma54_activ_2 PF14532.6 OQR90451.1 - 0.015 15.5 0.0 0.036 14.2 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_7 PF12775.7 OQR90451.1 - 0.015 14.8 0.1 0.09 12.3 0.0 2.1 2 0 0 2 2 2 0 P-loop containing dynein motor region RuvB_N PF05496.12 OQR90451.1 - 0.019 14.7 0.0 0.077 12.7 0.0 2.0 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 OQR90451.1 - 0.023 15.2 1.4 0.11 13.0 0.0 2.9 2 0 0 2 2 1 0 AAA domain Parvo_NS1 PF01057.17 OQR90451.1 - 0.038 13.1 0.0 0.083 12.0 0.0 1.5 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Mg_chelatase PF01078.21 OQR90451.1 - 0.049 13.0 0.0 0.11 11.9 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI C1_1 PF00130.22 OQR90451.1 - 0.13 12.2 3.5 0.28 11.1 3.5 1.6 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Sigma54_activat PF00158.26 OQR90451.1 - 0.14 11.9 0.0 0.49 10.1 0.0 1.9 2 1 0 2 2 2 0 Sigma-54 interaction domain CHD5 PF04420.14 OQR90451.1 - 0.31 10.9 1.0 0.92 9.4 1.0 1.8 1 0 0 1 1 1 0 CHD5-like protein ABC_tran PF00005.27 OQR90451.1 - 1.9 9.0 0.0 1.9 9.0 0.0 3.7 4 1 0 4 4 3 0 ABC transporter zf-RING_9 PF13901.6 OQR90451.1 - 5.2 7.0 9.5 5.1 7.0 7.2 2.2 2 0 0 2 2 1 0 Putative zinc-RING and/or ribbon zf-RING_2 PF13639.6 OQR90451.1 - 7.9 6.9 11.6 12 6.3 10.2 2.1 2 0 0 2 2 2 0 Ring finger domain zf-RING_2 PF13639.6 OQR90452.1 - 1.2e-12 48.0 2.5 3.1e-12 46.6 2.5 1.8 1 0 0 1 1 1 1 Ring finger domain PX PF00787.24 OQR90452.1 - 3.2e-09 36.8 0.1 4.9e-09 36.2 0.1 1.3 1 0 0 1 1 1 1 PX domain zf-rbx1 PF12678.7 OQR90452.1 - 4.2e-08 33.3 1.4 1.2e-07 31.9 1.4 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_3 PF13920.6 OQR90452.1 - 4.2e-07 29.7 1.3 7.8e-07 28.9 1.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 OQR90452.1 - 4.3e-07 29.7 2.3 4.3e-07 29.7 2.3 1.9 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OQR90452.1 - 1.3e-06 28.3 1.1 3e-06 27.1 1.1 1.7 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 OQR90452.1 - 3.5e-06 26.8 4.3 1e-05 25.3 4.3 1.9 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 OQR90452.1 - 7.6e-06 25.9 0.2 7.6e-06 25.9 0.2 2.9 4 0 0 4 4 2 1 RING-type zinc-finger zf-C3HC4 PF00097.25 OQR90452.1 - 1e-05 25.3 1.4 1e-05 25.3 1.4 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 OQR90452.1 - 1.4e-05 24.7 0.5 1.4e-05 24.7 0.5 2.7 2 0 0 2 2 2 1 RING-like zinc finger FANCL_C PF11793.8 OQR90452.1 - 0.0026 17.9 3.5 0.011 15.9 3.5 2.1 1 1 0 1 1 1 1 FANCL C-terminal domain zf-ANAPC11 PF12861.7 OQR90452.1 - 0.0051 16.8 2.4 0.016 15.3 2.4 1.9 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_ribbon_17 PF17120.5 OQR90452.1 - 0.0099 15.5 4.0 0.0099 15.5 4.0 2.5 2 1 1 3 3 3 1 Zinc-ribbon, C4HC2 type zf-C3H2C3 PF17122.5 OQR90452.1 - 0.013 15.5 0.8 0.013 15.5 0.8 2.3 2 1 0 2 2 1 0 Zinc-finger RINGv PF12906.7 OQR90452.1 - 0.017 15.2 1.2 0.053 13.6 1.2 1.9 1 1 0 1 1 1 0 RING-variant domain zinc_ribbon_16 PF17034.5 OQR90452.1 - 0.032 14.4 2.5 0.035 14.3 0.7 1.9 1 1 1 2 2 2 0 Zinc-ribbon like family zf-C3HC4_4 PF15227.6 OQR90452.1 - 0.09 13.0 4.6 0.71 10.1 4.6 2.6 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING Prok-RING_1 PF14446.6 OQR90452.1 - 0.21 11.5 5.1 0.25 11.3 0.3 2.3 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 zf-RING_4 PF14570.6 OQR90452.1 - 0.33 10.8 2.2 1.2 9.0 2.2 2.0 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-AD PF07776.15 OQR90452.1 - 0.61 10.4 5.1 0.4 10.9 0.2 2.4 2 0 0 2 2 2 0 Zinc-finger associated domain (zf-AD) Glyco_transf_20 PF00982.21 OQR90471.1 - 5.7e-88 295.7 0.0 8.1e-88 295.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.16 OQR90471.1 - 1.6e-42 145.2 0.0 2.6e-42 144.6 0.0 1.3 1 0 0 1 1 1 1 Trehalose-phosphatase Polysacc_synt_C PF14667.6 OQR90472.1 - 0.013 15.5 2.3 0.015 15.3 2.3 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis C-terminal domain Oxidored_q3 PF00499.20 OQR90472.1 - 0.075 12.8 1.2 5.4 6.7 0.0 2.0 2 0 0 2 2 2 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 Abhydrolase_9_N PF15420.6 OQR90472.1 - 0.084 12.9 0.6 2.8 7.9 0.1 2.0 2 0 0 2 2 2 0 Alpha/beta-hydrolase family N-terminus Babuvirus_MP PF07234.11 OQR90472.1 - 0.33 11.1 0.2 0.33 11.1 0.2 2.1 1 1 1 2 2 2 0 Movement and RNA silencing protein Dynein_light PF01221.18 OQR90473.1 - 4.1e-24 84.7 0.6 4.8e-24 84.5 0.6 1.1 1 0 0 1 1 1 1 Dynein light chain type 1 Metallophos PF00149.28 OQR90474.1 - 1.3e-15 58.4 0.7 2.3e-15 57.6 0.7 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_C PF14008.6 OQR90474.1 - 1.7e-07 32.0 0.2 5.4e-07 30.4 0.2 2.0 1 0 0 1 1 1 1 Iron/zinc purple acid phosphatase-like protein C Metallophos_2 PF12850.7 OQR90474.1 - 0.00032 20.9 0.0 1.1 9.5 0.0 2.2 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase superfamily domain Pur_ac_phosph_N PF16656.5 OQR90474.1 - 0.00038 21.0 14.6 0.0004 20.9 7.8 3.1 2 1 0 2 2 2 1 Purple acid Phosphatase, N-terminal domain ZZ PF00569.17 OQR90478.1 - 1.4e-09 37.6 6.3 2.3e-09 36.9 6.3 1.3 1 0 0 1 1 1 1 Zinc finger, ZZ type C1_2 PF03107.16 OQR90478.1 - 0.0004 20.7 5.8 0.00085 19.6 5.8 1.5 1 0 0 1 1 1 1 C1 domain Band_7 PF01145.25 OQR90479.1 - 4.2e-26 92.1 0.1 4.2e-26 92.1 0.1 2.4 2 1 0 2 2 2 1 SPFH domain / Band 7 family Band_7_1 PF13421.6 OQR90479.1 - 0.045 13.5 0.1 0.11 12.1 0.1 1.7 1 0 0 1 1 1 0 SPFH domain-Band 7 family Flot PF15975.5 OQR90479.1 - 1.1 9.5 15.0 2.2 8.5 5.4 2.4 1 1 1 2 2 2 0 Flotillin DivIVA PF05103.13 OQR90479.1 - 1.4 9.0 9.8 7.2 6.7 3.4 2.2 1 1 1 2 2 2 0 DivIVA protein TPR_19 PF14559.6 OQR90480.1 - 1.3e-05 25.7 0.1 0.22 12.0 0.0 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.6 OQR90480.1 - 3.4e-05 23.9 2.0 0.022 15.1 0.8 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.6 OQR90480.1 - 0.0044 17.3 1.5 1.3 9.4 0.0 3.1 3 1 0 3 3 3 1 Tetratricopeptide repeat Coatomer_E PF04733.14 OQR90480.1 - 0.0057 16.1 0.0 0.01 15.2 0.0 1.3 1 0 0 1 1 1 1 Coatomer epsilon subunit TPR_16 PF13432.6 OQR90480.1 - 0.0097 16.5 0.0 0.66 10.7 0.0 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.17 OQR90480.1 - 0.017 15.2 5.0 0.78 10.0 0.1 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.6 OQR90480.1 - 0.14 12.8 0.7 1.7 9.5 0.1 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_20 PF14561.6 OQR90480.1 - 0.17 12.3 0.0 3.7 7.9 0.0 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.28 OQR90480.1 - 0.73 9.8 2.4 2.7 7.9 0.2 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF4029 PF13221.6 OQR90480.1 - 1.1 10.0 7.8 0.84 10.3 5.0 2.3 2 0 0 2 2 1 0 Protein of unknown function (DUF4029) CitMHS PF03600.16 OQR90480.1 - 3.3 6.8 13.2 5.7 6.0 13.2 1.4 1 0 0 1 1 1 0 Citrate transporter Myosin_head PF00063.21 OQR90481.1 - 2.3e-211 703.6 0.0 3.5e-211 703.0 0.0 1.2 1 0 0 1 1 1 1 Myosin head (motor domain) IQ PF00612.27 OQR90481.1 - 2.3e-05 23.8 37.0 0.019 14.7 3.8 5.9 6 0 0 6 6 6 4 IQ calmodulin-binding motif Myosin_N PF02736.19 OQR90481.1 - 0.00062 19.5 0.0 0.0014 18.4 0.0 1.7 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain AAA_16 PF13191.6 OQR90481.1 - 0.00096 19.6 1.2 0.011 16.1 0.0 2.7 2 0 0 2 2 2 1 AAA ATPase domain Zeta_toxin PF06414.12 OQR90481.1 - 0.011 15.0 0.0 0.011 15.0 0.0 2.2 2 1 1 3 3 3 0 Zeta toxin AAA_22 PF13401.6 OQR90481.1 - 0.021 15.1 2.3 0.23 11.7 0.0 3.2 3 0 0 3 3 3 0 AAA domain DUF87 PF01935.17 OQR90481.1 - 0.022 14.8 6.3 0.35 10.9 0.1 3.4 3 0 0 3 3 3 0 Helicase HerA, central domain AAA_6 PF12774.7 OQR90481.1 - 0.023 13.7 2.7 0.43 9.5 0.0 2.9 2 1 1 3 3 3 0 Hydrolytic ATP binding site of dynein motor region RPN2_C PF18004.1 OQR90481.1 - 0.065 13.2 9.7 0.15 12.0 9.7 1.5 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain AAA_7 PF12775.7 OQR90481.1 - 0.096 12.2 0.4 0.48 9.9 0.0 2.2 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_18 PF13238.6 OQR90481.1 - 0.13 12.8 0.0 0.67 10.5 0.0 2.4 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 OQR90481.1 - 0.57 10.6 7.2 7.7 7.0 7.1 2.4 2 0 0 2 2 2 0 AAA domain Myosin_head PF00063.21 OQR90483.1 - 2.3e-42 145.1 0.1 3e-42 144.7 0.1 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) Zeta_toxin PF06414.12 OQR90483.1 - 0.0018 17.6 0.1 0.0028 17.0 0.1 1.2 1 0 0 1 1 1 1 Zeta toxin Myosin_N PF02736.19 OQR90483.1 - 0.0024 17.7 0.7 0.0042 16.9 0.7 1.4 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain AAA_16 PF13191.6 OQR90483.1 - 0.0095 16.3 0.0 0.016 15.6 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 OQR90483.1 - 0.023 15.0 0.0 0.042 14.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 OQR90483.1 - 0.052 13.6 0.0 0.12 12.3 0.0 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Sigma54_activat PF00158.26 OQR90483.1 - 0.067 12.9 0.1 0.14 11.9 0.0 1.7 2 0 0 2 2 2 0 Sigma-54 interaction domain RNA_helicase PF00910.22 OQR90483.1 - 0.076 13.4 0.0 0.17 12.3 0.0 1.6 1 0 0 1 1 1 0 RNA helicase CbiA PF01656.23 OQR90483.1 - 0.09 12.8 0.4 0.24 11.5 0.2 1.8 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_10 PF12846.7 OQR90483.1 - 0.13 11.2 0.0 0.18 10.7 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain DTW PF03942.15 OQR90484.1 - 1.6e-43 148.7 1.5 2.4e-43 148.2 1.5 1.2 1 0 0 1 1 1 1 DTW domain Ribo_biogen_C PF04034.13 OQR90484.1 - 0.00017 21.3 0.0 0.00032 20.4 0.0 1.5 1 0 0 1 1 1 1 Ribosome biogenesis protein, C-terminal Peptidase_M23 PF01551.22 OQR90484.1 - 0.13 12.5 0.3 1.7 8.9 0.0 2.2 2 0 0 2 2 2 0 Peptidase family M23 Pro_isomerase PF00160.21 OQR90485.1 - 2.3e-49 167.7 0.2 1.7e-48 164.9 0.0 2.2 2 0 0 2 2 2 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD WD40 PF00400.32 OQR90485.1 - 7.6e-14 51.9 0.9 9.7e-05 23.1 0.0 4.4 4 0 0 4 4 4 2 WD domain, G-beta repeat Ge1_WD40 PF16529.5 OQR90485.1 - 2.5e-07 30.0 0.3 0.00079 18.5 0.0 2.3 1 1 1 2 2 2 2 WD40 region of Ge1, enhancer of mRNA-decapping protein ANAPC4_WD40 PF12894.7 OQR90485.1 - 0.00084 19.6 0.0 0.13 12.6 0.0 3.7 3 1 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain Cellulase PF00150.18 OQR90486.1 - 1.3e-37 129.8 6.9 5.1e-23 81.9 0.8 2.2 2 0 0 2 2 2 2 Cellulase (glycosyl hydrolase family 5) Cellulase PF00150.18 OQR90487.1 - 3.9e-25 88.8 0.0 6.9e-25 88.0 0.0 1.4 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Thioredoxin_6 PF13848.6 OQR90487.1 - 4.7e-12 46.2 1.9 6.5e-11 42.5 1.1 2.4 2 0 0 2 2 2 1 Thioredoxin-like domain Thioredoxin PF00085.20 OQR90487.1 - 0.0044 17.0 0.0 0.042 13.8 0.0 2.6 3 0 0 3 3 3 1 Thioredoxin La PF05383.17 OQR90488.1 - 1.1e-15 57.4 0.1 2.5e-15 56.3 0.1 1.6 1 0 0 1 1 1 1 La domain Anoctamin PF04547.12 OQR90491.1 - 1.4e-64 218.6 11.4 2.2e-64 218.0 11.4 1.2 1 0 0 1 1 1 1 Calcium-activated chloride channel Spt5-NGN PF03439.13 OQR90491.1 - 9e-19 67.2 0.0 2.1e-18 66.0 0.0 1.7 1 0 0 1 1 1 1 Early transcription elongation factor of RNA pol II, NGN section C2 PF00168.30 OQR90491.1 - 2.9e-16 59.6 0.0 1.1e-15 57.8 0.0 2.1 2 0 0 2 2 2 1 C2 domain KOW PF00467.29 OQR90491.1 - 2.5e-13 49.5 32.5 9.2e-06 25.4 0.2 7.1 7 0 0 7 7 7 4 KOW motif RSN1_7TM PF02714.15 OQR90491.1 - 0.0002 20.8 3.1 0.0002 20.8 3.1 2.0 3 0 0 3 3 3 1 Calcium-dependent channel, 7TM region, putative phosphate Spt5_N PF11942.8 OQR90491.1 - 0.00089 20.2 14.1 0.00089 20.2 14.1 2.9 2 0 0 2 2 2 1 Spt5 transcription elongation factor, acidic N-terminal DUF3912 PF13051.6 OQR90491.1 - 0.0048 17.1 5.1 0.049 13.9 0.1 3.1 3 0 0 3 3 3 1 Protein of unknown function (DUF3912) DUF150_C PF17384.2 OQR90491.1 - 0.75 10.0 3.4 7.3 6.8 0.2 3.4 3 0 0 3 3 3 0 RimP C-terminal SH3 domain PhoLip_ATPase_C PF16212.5 OQR90492.1 - 3.1e-08 33.7 8.7 4.1e-08 33.3 8.7 1.1 1 0 0 1 1 1 1 Phospholipid-translocating P-type ATPase C-terminal FYVE PF01363.21 OQR90501.1 - 4.6e-10 39.5 25.5 3.6e-07 30.2 16.7 2.7 2 0 0 2 2 2 2 FYVE zinc finger DZR PF12773.7 OQR90501.1 - 4.4 7.4 23.7 1.6 8.8 1.4 3.2 2 1 0 2 2 2 0 Double zinc ribbon TPMT PF05724.11 OQR90502.1 - 1e-32 113.6 0.3 1.3e-31 110.0 0.3 1.9 1 1 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_25 PF13649.6 OQR90502.1 - 1e-09 38.9 0.0 1.5e-09 38.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OQR90502.1 - 2.2e-07 30.8 0.0 3.2e-07 30.3 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OQR90502.1 - 1.9e-06 27.8 0.0 3.8e-06 26.8 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OQR90502.1 - 2.9e-06 28.0 0.0 4.6e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OQR90502.1 - 8.9e-06 26.3 0.0 1.5e-05 25.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain TehB PF03848.14 OQR90502.1 - 0.0027 17.1 0.0 0.0037 16.7 0.0 1.2 1 0 0 1 1 1 1 Tellurite resistance protein TehB N2227 PF07942.12 OQR90502.1 - 0.02 14.1 0.0 0.029 13.6 0.0 1.3 1 0 0 1 1 1 0 N2227-like protein UPF0506 PF11703.8 OQR90503.1 - 1.5 9.3 16.7 6.8 7.1 7.2 2.9 1 1 2 3 3 3 0 UPF0506 Ank_2 PF12796.7 OQR90504.1 - 2.8e-11 43.8 0.6 7.7e-11 42.4 0.3 1.8 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OQR90504.1 - 3e-09 36.9 2.4 2.6e-05 24.4 0.5 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQR90504.1 - 3.7e-09 36.1 0.7 0.0049 17.3 0.0 4.1 4 0 0 4 4 4 2 Ankyrin repeat Ank_4 PF13637.6 OQR90504.1 - 6.8e-09 36.1 6.7 1.5e-06 28.6 0.4 3.7 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 OQR90504.1 - 6.3e-05 23.2 4.8 0.0055 17.1 0.1 2.9 3 0 0 3 3 3 2 Ankyrin repeat zf-C3HC4_3 PF13920.6 OQR90505.1 - 8.4e-15 54.4 11.9 1.5e-14 53.5 11.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Ank_2 PF12796.7 OQR90505.1 - 5e-14 52.7 0.1 1.4e-13 51.2 0.1 1.8 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQR90505.1 - 1.2e-13 51.3 0.2 2.2e-09 37.7 0.0 2.7 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 OQR90505.1 - 1.6e-13 50.6 0.3 4.9e-07 29.9 0.1 2.7 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQR90505.1 - 7.6e-13 47.4 0.1 1.9e-05 24.7 0.0 2.9 2 0 0 2 2 2 2 Ankyrin repeat Ank PF00023.30 OQR90505.1 - 7.9e-13 48.2 0.1 1.4e-05 25.3 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeat Prok-RING_4 PF14447.6 OQR90505.1 - 1.7e-06 27.8 10.7 3.1e-06 27.0 10.7 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 OQR90505.1 - 5e-06 26.8 10.9 5e-06 26.8 10.9 1.9 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 OQR90505.1 - 0.00017 21.3 10.8 0.00039 20.2 10.8 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 OQR90505.1 - 0.00018 21.3 11.2 0.00039 20.2 11.2 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OQR90505.1 - 0.004 17.1 11.3 0.01 15.7 11.3 1.7 1 0 0 1 1 1 1 zinc-RING finger domain ABC_tran_CTD PF16326.5 OQR90505.1 - 0.11 12.8 3.6 0.13 12.6 2.0 2.0 2 0 0 2 2 2 0 ABC transporter C-terminal domain Rubredoxin_2 PF18073.1 OQR90505.1 - 0.32 10.7 3.9 0.14 11.9 0.7 2.0 2 0 0 2 2 2 0 Rubredoxin metal binding domain Holin_BhlA PF10960.8 OQR90505.1 - 0.33 10.9 2.3 0.74 9.8 2.3 1.5 1 0 0 1 1 1 0 BhlA holin family zf-RING_4 PF14570.6 OQR90505.1 - 0.81 9.5 9.1 2 8.3 9.1 1.7 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_UBOX PF13445.6 OQR90505.1 - 2.2 8.4 6.9 1.6 8.8 4.4 2.1 1 1 1 2 2 2 0 RING-type zinc-finger zf-P11 PF03854.14 OQR90505.1 - 5.9 6.6 10.9 0.28 10.9 4.7 2.0 2 0 0 2 2 2 0 P-11 zinc finger Sulfotransfer_3 PF13469.6 OQR90506.1 - 4.7e-35 121.9 0.2 1.7e-34 120.1 0.2 1.8 1 1 0 1 1 1 1 Sulfotransferase family Sulfotransfer_1 PF00685.27 OQR90506.1 - 7.4e-11 42.0 0.2 1.6e-10 40.9 0.2 1.5 1 1 0 1 1 1 1 Sulfotransferase domain AAA PF00004.29 OQR90514.1 - 1.3e-30 106.5 0.0 2.9e-21 76.3 0.0 2.8 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 OQR90514.1 - 2.2e-07 31.4 0.1 0.00037 20.9 0.1 3.3 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 OQR90514.1 - 4.1e-06 27.1 2.1 0.00027 21.2 0.1 3.2 3 1 0 3 3 2 1 AAA domain AAA_5 PF07728.14 OQR90514.1 - 0.0003 20.8 0.0 0.029 14.4 0.0 3.3 3 0 0 3 3 2 1 AAA domain (dynein-related subfamily) AAA_24 PF13479.6 OQR90514.1 - 0.00034 20.4 0.0 0.45 10.2 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_7 PF12775.7 OQR90514.1 - 0.00059 19.4 0.2 0.055 13.0 0.1 2.5 2 0 0 2 2 2 1 P-loop containing dynein motor region RsgA_GTPase PF03193.16 OQR90514.1 - 0.0013 18.7 0.1 0.29 11.0 0.0 2.6 2 0 0 2 2 2 1 RsgA GTPase Sigma54_activat PF00158.26 OQR90514.1 - 0.0017 18.1 0.8 2.7 7.7 0.0 3.0 2 1 0 3 3 3 2 Sigma-54 interaction domain AAA_14 PF13173.6 OQR90514.1 - 0.0019 18.3 0.0 0.0076 16.3 0.0 2.1 2 0 0 2 2 1 1 AAA domain DUF815 PF05673.13 OQR90514.1 - 0.0023 17.1 0.1 0.7 9.0 0.0 2.6 2 0 0 2 2 2 1 Protein of unknown function (DUF815) IstB_IS21 PF01695.17 OQR90514.1 - 0.0026 17.5 0.0 3.1 7.5 0.0 2.7 2 0 0 2 2 2 2 IstB-like ATP binding protein RNA_helicase PF00910.22 OQR90514.1 - 0.0032 17.8 0.0 1.5 9.2 0.0 2.7 2 0 0 2 2 2 1 RNA helicase Rad17 PF03215.15 OQR90514.1 - 0.0032 17.4 0.0 1.1 9.2 0.0 2.6 2 0 0 2 2 2 1 Rad17 P-loop domain ABC_tran PF00005.27 OQR90514.1 - 0.0045 17.5 0.1 5 7.6 0.0 3.9 4 0 0 4 4 4 1 ABC transporter AAA_2 PF07724.14 OQR90514.1 - 0.0061 16.7 0.0 0.09 12.9 0.0 2.6 3 0 0 3 3 2 1 AAA domain (Cdc48 subfamily) Zot PF05707.12 OQR90514.1 - 0.0099 15.5 0.1 0.051 13.2 0.0 1.9 1 1 0 2 2 2 1 Zonular occludens toxin (Zot) AAA_18 PF13238.6 OQR90514.1 - 0.016 15.7 1.5 9.9 6.7 0.0 3.4 4 0 0 4 4 3 0 AAA domain NACHT PF05729.12 OQR90514.1 - 0.021 14.7 0.1 1.2 9.1 0.0 3.2 3 0 0 3 3 3 0 NACHT domain AAA_6 PF12774.7 OQR90514.1 - 0.029 13.4 0.1 2 7.3 0.1 2.5 2 0 0 2 2 2 0 Hydrolytic ATP binding site of dynein motor region RuvB_N PF05496.12 OQR90514.1 - 0.035 13.9 0.0 12 5.6 0.0 2.6 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain AAA_25 PF13481.6 OQR90514.1 - 0.042 13.4 0.0 2 7.9 0.0 2.8 2 0 0 2 2 2 0 AAA domain CbiA PF01656.23 OQR90514.1 - 0.042 13.9 0.0 0.13 12.3 0.0 2.0 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_33 PF13671.6 OQR90514.1 - 0.05 13.8 1.8 0.13 12.5 0.0 2.6 3 0 0 3 3 2 0 AAA domain AAA_19 PF13245.6 OQR90514.1 - 0.054 13.8 0.2 0.27 11.6 0.2 2.2 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 OQR90514.1 - 0.081 12.7 2.4 7.3 6.4 0.3 2.6 2 0 0 2 2 2 0 P-loop containing region of AAA domain SRP54 PF00448.22 OQR90514.1 - 0.092 12.4 1.6 0.16 11.5 0.2 2.2 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain T2SSE PF00437.20 OQR90514.1 - 0.16 11.0 2.1 0.21 10.6 0.1 2.2 3 0 0 3 3 3 0 Type II/IV secretion system protein AAA_30 PF13604.6 OQR90514.1 - 0.16 11.7 1.2 0.24 11.1 0.0 1.9 2 0 0 2 2 2 0 AAA domain FYDLN_acid PF09538.10 OQR90514.1 - 6.2 7.5 8.5 18 6.1 8.5 1.7 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) DUF3453 PF11935.8 OQR90515.1 - 6.9e-05 22.6 0.1 0.00015 21.5 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3453) DDE_Tnp_4 PF13359.6 OQR90516.1 - 0.00017 21.3 0.0 0.0003 20.5 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease Adeno_E3_CR2 PF02439.15 OQR90517.1 - 7e-05 22.5 0.0 0.00015 21.4 0.0 1.5 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 SKG6 PF08693.10 OQR90517.1 - 0.0072 15.7 1.4 0.0072 15.7 1.4 1.9 2 0 0 2 2 2 1 Transmembrane alpha-helix domain Glycophorin_A PF01102.18 OQR90517.1 - 0.01 16.0 0.1 0.021 15.0 0.1 1.4 1 0 0 1 1 1 0 Glycophorin A Gram_pos_anchor PF00746.21 OQR90517.1 - 0.018 15.0 0.2 0.04 13.8 0.2 1.6 1 0 0 1 1 1 0 LPXTG cell wall anchor motif EphA2_TM PF14575.6 OQR90517.1 - 0.025 15.5 0.0 0.38 11.6 0.0 2.3 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Pkinase_Tyr PF07714.17 OQR90517.1 - 0.033 13.5 0.0 0.051 12.9 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase Syndecan PF01034.20 OQR90517.1 - 0.075 13.0 0.0 0.14 12.1 0.0 1.4 1 0 0 1 1 1 0 Syndecan domain Protocadherin PF08374.11 OQR90517.1 - 0.086 12.8 0.0 0.14 12.1 0.0 1.3 1 0 0 1 1 1 0 Protocadherin DUF3188 PF11384.8 OQR90517.1 - 0.18 11.5 0.6 0.34 10.7 0.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3188) Defb50 PF17546.2 OQR90517.1 - 1.5 8.8 5.4 1.1 9.2 1.5 2.7 3 0 0 3 3 3 0 Beta defensin 50 DLH PF01738.18 OQR90520.1 - 1.4e-16 60.7 0.4 1e-15 57.9 0.0 2.7 2 0 0 2 2 2 1 Dienelactone hydrolase family Esterase PF00756.20 OQR90520.1 - 0.043 13.5 0.1 0.23 11.1 0.0 2.2 2 0 0 2 2 2 0 Putative esterase Hydrolase_4 PF12146.8 OQR90520.1 - 0.065 12.5 0.2 8.2 5.6 0.0 3.3 2 1 1 3 3 3 0 Serine aminopeptidase, S33 Glyco_transf_4 PF13439.6 OQR90520.1 - 0.1 12.6 0.0 0.22 11.5 0.0 1.5 1 0 0 1 1 1 0 Glycosyltransferase Family 4 Peptidase_S9 PF00326.21 OQR90520.1 - 0.11 11.9 0.9 0.86 9.0 0.0 2.6 2 1 1 3 3 3 0 Prolyl oligopeptidase family MAP70 PF07058.11 OQR90521.1 - 0.035 12.9 0.4 0.042 12.6 0.4 1.0 1 0 0 1 1 1 0 Microtubule-associated protein 70 AA_permease_2 PF13520.6 OQR90522.1 - 6.1e-47 160.4 47.8 8.2e-47 160.0 47.8 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 OQR90523.1 - 1.2e-46 159.4 45.9 1.6e-46 159.1 45.9 1.1 1 0 0 1 1 1 1 Amino acid permease Sid-5 PF17204.3 OQR90523.1 - 0.16 12.2 3.5 0.44 10.7 0.2 2.7 2 0 0 2 2 2 0 Sid-5 family ParcG PF10274.9 OQR90524.1 - 1.9e-70 236.7 0.0 3.8e-70 235.7 0.0 1.5 1 0 0 1 1 1 1 Parkin co-regulated protein TIG PF01833.24 OQR90524.1 - 7.4e-29 99.7 69.7 2.1e-06 27.7 0.2 19.6 22 0 0 22 22 22 10 IPT/TIG domain C2 PF00168.30 OQR90524.1 - 2.5e-09 37.4 0.0 6.4e-09 36.0 0.0 1.8 1 0 0 1 1 1 1 C2 domain GPHH PF16905.5 OQR90524.1 - 0.028 14.2 0.0 0.1 12.4 0.0 2.0 1 0 0 1 1 1 0 Voltage-dependent L-type calcium channel, IQ-associated CEP76-C2 PF15627.6 OQR90524.1 - 0.065 12.8 0.0 0.16 11.5 0.0 1.6 1 0 0 1 1 1 0 CEP76 C2 domain EF-hand_7 PF13499.6 OQR90524.1 - 0.18 12.3 0.1 11 6.6 0.0 3.1 3 0 0 3 3 3 0 EF-hand domain pair ABC_tran PF00005.27 OQR90526.1 - 4.6e-54 182.7 0.3 4.2e-26 92.1 0.0 2.7 3 0 0 3 3 2 2 ABC transporter AAA_21 PF13304.6 OQR90526.1 - 1e-14 55.1 2.6 0.0014 18.5 0.1 4.4 5 0 0 5 5 4 3 AAA domain, putative AbiEii toxin, Type IV TA system ABC_tran_Xtn PF12848.7 OQR90526.1 - 1.1e-12 47.8 9.3 6.4e-10 38.9 4.4 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 OQR90526.1 - 4.1e-07 29.7 7.9 0.2 11.1 0.0 4.1 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 OQR90526.1 - 1.5e-06 27.8 0.8 0.0031 17.2 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 OQR90526.1 - 4.4e-06 26.8 1.9 0.0045 17.1 0.2 2.6 2 1 0 2 2 2 2 50S ribosome-binding GTPase AAA_23 PF13476.6 OQR90526.1 - 4.5e-06 27.3 10.7 0.0001 22.9 0.0 3.5 3 1 1 4 4 4 2 AAA domain RsgA_GTPase PF03193.16 OQR90526.1 - 2.2e-05 24.4 2.1 0.012 15.5 0.1 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_16 PF13191.6 OQR90526.1 - 5.9e-05 23.5 0.0 0.15 12.5 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain AAA_13 PF13166.6 OQR90526.1 - 0.00027 19.7 0.1 2.1 6.9 0.1 3.3 2 1 0 3 3 3 1 AAA domain NB-ARC PF00931.22 OQR90526.1 - 0.00034 19.9 0.1 0.2 10.8 0.1 2.8 2 2 0 2 2 2 1 NB-ARC domain AAA_18 PF13238.6 OQR90526.1 - 0.00045 20.8 0.4 1.8 9.1 0.0 3.4 3 0 0 3 3 3 1 AAA domain ATPase_2 PF01637.18 OQR90526.1 - 0.00076 19.5 0.0 0.049 13.5 0.0 2.4 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea MeaB PF03308.16 OQR90526.1 - 0.0011 18.1 0.1 0.93 8.4 0.0 2.3 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA PF00004.29 OQR90526.1 - 0.0012 19.3 0.0 0.62 10.5 0.0 2.9 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 OQR90526.1 - 0.0013 19.1 0.2 1.1 9.6 0.0 2.5 2 0 0 2 2 2 1 RNA helicase AAA_15 PF13175.6 OQR90526.1 - 0.0021 17.8 0.0 1.6 8.3 0.0 2.4 2 1 0 2 2 2 2 AAA ATPase domain AAA_27 PF13514.6 OQR90526.1 - 0.0022 17.6 0.3 0.052 13.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 OQR90526.1 - 0.0041 16.9 0.0 1.5 8.5 0.0 2.4 2 0 0 2 2 2 1 AAA domain SbcCD_C PF13558.6 OQR90526.1 - 0.0049 17.1 0.6 10 6.4 0.0 4.0 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit KAP_NTPase PF07693.14 OQR90526.1 - 0.0055 16.0 0.0 0.4 9.9 0.0 2.2 1 1 1 2 2 2 1 KAP family P-loop domain Roc PF08477.13 OQR90526.1 - 0.0092 16.2 3.3 3.6 7.8 0.1 3.8 5 0 0 5 5 3 1 Ras of Complex, Roc, domain of DAPkinase AAA_24 PF13479.6 OQR90526.1 - 0.0095 15.7 0.3 1.7 8.3 0.2 2.4 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 OQR90526.1 - 0.012 15.9 2.3 0.17 12.1 0.0 3.0 3 1 0 3 3 2 0 AAA domain AAA_14 PF13173.6 OQR90526.1 - 0.017 15.2 0.0 1.5 8.8 0.0 3.2 3 1 1 4 4 3 0 AAA domain Rad17 PF03215.15 OQR90526.1 - 0.024 14.5 0.0 0.31 11.0 0.0 2.5 3 0 0 3 3 2 0 Rad17 P-loop domain MukB PF04310.12 OQR90526.1 - 0.027 14.3 0.5 0.5 10.1 0.0 2.8 3 0 0 3 3 3 0 MukB N-terminal AAA_28 PF13521.6 OQR90526.1 - 0.039 14.2 1.9 3.1 8.0 0.0 2.8 3 0 0 3 3 2 0 AAA domain Dynamin_N PF00350.23 OQR90526.1 - 0.046 13.8 1.9 2 8.5 0.0 2.7 2 1 0 2 2 2 0 Dynamin family Zeta_toxin PF06414.12 OQR90526.1 - 0.056 12.7 0.2 0.43 9.8 0.0 2.1 2 0 0 2 2 2 0 Zeta toxin AAA_7 PF12775.7 OQR90526.1 - 0.086 12.3 0.1 7.8 6.0 0.0 2.2 2 0 0 2 2 2 0 P-loop containing dynein motor region NACHT PF05729.12 OQR90526.1 - 0.09 12.7 0.6 8.7 6.2 0.0 2.4 2 0 0 2 2 2 0 NACHT domain AAA_33 PF13671.6 OQR90526.1 - 0.092 12.9 0.0 7.2 6.8 0.0 3.0 3 0 0 3 3 2 0 AAA domain Ploopntkinase3 PF18751.1 OQR90526.1 - 0.097 12.6 0.1 8.6 6.2 0.0 2.6 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 FeoB_N PF02421.18 OQR90526.1 - 0.15 11.6 0.6 4.3 6.8 0.1 2.4 2 0 0 2 2 2 0 Ferrous iron transport protein B DUF87 PF01935.17 OQR90526.1 - 0.17 11.9 7.2 0.55 10.3 0.7 3.2 4 0 0 4 4 3 0 Helicase HerA, central domain PRK PF00485.18 OQR90526.1 - 0.23 11.2 0.5 10 5.8 0.0 2.4 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family Gtr1_RagA PF04670.12 OQR90526.1 - 0.55 9.5 2.3 1.3 8.4 0.0 2.4 3 0 0 3 3 3 0 Gtr1/RagA G protein conserved region Na_H_Exchanger PF00999.21 OQR90527.1 - 3.1e-23 82.2 30.0 4.4e-23 81.7 30.0 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family GTP_EFTU PF00009.27 OQR90528.1 - 2.1e-49 167.7 0.0 3.7e-49 166.9 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain LepA_C PF06421.12 OQR90528.1 - 1.9e-42 143.8 1.3 4.2e-42 142.6 1.3 1.6 1 0 0 1 1 1 1 GTP-binding protein LepA C-terminus EFG_C PF00679.24 OQR90528.1 - 1.3e-17 63.6 0.1 3e-17 62.4 0.1 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 OQR90528.1 - 2.5e-09 37.4 0.1 5.3e-09 36.3 0.1 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 OQR90528.1 - 1.5e-05 25.0 0.1 3e-05 24.1 0.1 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 OQR90528.1 - 0.012 15.1 0.0 0.035 13.5 0.0 1.9 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit Dynein_light PF01221.18 OQR90529.1 - 1e-24 86.6 0.4 1.2e-24 86.5 0.4 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 HLH PF00010.26 OQR90530.1 - 6.5e-09 35.6 1.3 1.1e-08 34.9 1.3 1.4 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain PAS PF00989.25 OQR90530.1 - 8.5e-05 22.5 0.1 0.0029 17.6 0.0 2.8 3 0 0 3 3 3 1 PAS fold PAS_4 PF08448.10 OQR90530.1 - 0.00015 22.0 0.0 0.00047 20.4 0.0 1.9 1 0 0 1 1 1 1 PAS fold PAS_9 PF13426.7 OQR90530.1 - 0.00064 19.9 0.0 0.0024 18.1 0.0 2.0 2 0 0 2 2 2 1 PAS domain PAS_8 PF13188.7 OQR90530.1 - 0.0026 17.8 0.0 0.0061 16.6 0.0 1.7 1 0 0 1 1 1 1 PAS domain PAS_3 PF08447.12 OQR90530.1 - 0.02 15.2 0.0 0.074 13.4 0.0 2.1 2 0 0 2 2 2 0 PAS fold Acyl-CoA_dh_2 PF08028.11 OQR90530.1 - 0.025 14.9 0.0 0.31 11.3 0.0 2.2 2 0 0 2 2 2 0 Acyl-CoA dehydrogenase, C-terminal domain Pkinase PF00069.25 OQR90533.1 - 1.6e-15 57.2 0.0 2.3e-15 56.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQR90533.1 - 2.7e-15 56.4 0.0 1.1e-14 54.4 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 OQR90533.1 - 0.034 13.5 0.0 0.061 12.7 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Peptidase_C69 PF03577.15 OQR90534.1 - 3.8e-52 177.6 0.7 6.2e-52 176.9 0.7 1.3 1 0 0 1 1 1 1 Peptidase family C69 Phage_attach PF05354.11 OQR90534.1 - 0.083 12.8 0.0 0.44 10.5 0.0 2.3 2 0 0 2 2 2 0 Phage Head-Tail Attachment DUF2431 PF10354.9 OQR90537.1 - 1.4e-35 123.0 0.0 2.5e-35 122.2 0.0 1.4 2 0 0 2 2 2 1 Domain of unknown function (DUF2431) FDX-ACB PF03147.14 OQR90537.1 - 0.00077 19.8 0.0 0.0016 18.8 0.0 1.5 1 0 0 1 1 1 1 Ferredoxin-fold anticodon binding domain IQ PF00612.27 OQR90540.1 - 0.0012 18.5 2.4 0.0088 15.8 2.4 2.6 1 0 0 1 1 1 1 IQ calmodulin-binding motif Minor_capsid_2 PF11114.8 OQR90540.1 - 0.09 12.8 0.0 0.25 11.4 0.0 1.7 1 0 0 1 1 1 0 Minor capsid protein HIT PF01230.23 OQR90541.1 - 1.3e-28 99.6 0.0 2.5e-28 98.7 0.0 1.5 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 OQR90541.1 - 1.5e-19 70.6 0.0 2.9e-19 69.6 0.0 1.5 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding DUF1148 PF06618.11 OQR90541.1 - 0.06 13.5 2.2 0.12 12.5 2.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1148) G5 PF07501.12 OQR90541.1 - 0.11 13.0 0.0 1.1 9.7 0.0 2.3 2 0 0 2 2 2 0 G5 domain Peptidase_C1 PF00112.23 OQR90542.1 - 4.1e-67 226.4 4.1 6.4e-67 225.8 4.1 1.3 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 OQR90542.1 - 7.8e-15 55.1 1.2 1.5e-14 54.1 1.2 1.5 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.15 OQR90542.1 - 1.8e-05 23.7 1.9 0.013 14.3 0.2 2.5 3 0 0 3 3 3 2 Peptidase C1-like family DUF4756 PF15948.5 OQR90542.1 - 0.063 13.1 0.2 0.14 12.0 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4756) MAD PF05557.13 OQR90542.1 - 0.16 10.3 0.0 0.22 9.9 0.0 1.1 1 0 0 1 1 1 0 Mitotic checkpoint protein DUF1279 PF06916.13 OQR90543.1 - 3.4e-14 53.1 2.9 8.7e-13 48.6 2.9 2.2 1 1 0 1 1 1 1 Protein of unknown function (DUF1279) FAA_hydrolase PF01557.18 OQR90544.1 - 2.7e-55 187.4 0.0 3.9e-55 186.9 0.0 1.2 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family KH_2 PF07650.17 OQR90544.1 - 0.059 13.2 1.6 0.39 10.6 0.1 2.4 2 0 0 2 2 2 0 KH domain FWWh PF14922.6 OQR90551.1 - 1.8e-10 40.9 1.9 3.1e-10 40.2 1.9 1.3 1 0 0 1 1 1 1 Protein of unknown function CHAD PF05235.14 OQR90551.1 - 0.6 10.1 3.5 1.2 9.1 1.9 2.2 2 1 0 2 2 2 0 CHAD domain ZapB PF06005.12 OQR90551.1 - 2.9 8.4 6.4 12 6.4 0.4 3.2 2 1 0 2 2 2 0 Cell division protein ZapB PDZ_6 PF17820.1 OQR90552.1 - 7e-12 45.0 0.0 0.00038 20.3 0.0 3.3 3 0 0 3 3 3 3 PDZ domain PDZ PF00595.24 OQR90552.1 - 1e-09 38.6 0.0 0.03 14.7 0.0 3.3 3 0 0 3 3 3 3 PDZ domain Tricorn_PDZ PF14685.6 OQR90552.1 - 0.00019 21.3 0.0 1.6 8.8 0.0 3.4 3 0 0 3 3 3 2 Tricorn protease PDZ domain PDZ_4 PF17816.1 OQR90552.1 - 0.052 13.9 0.0 1.9 8.9 0.0 2.9 2 1 1 3 3 3 0 PDZ domain Anoctamin PF04547.12 OQR90553.1 - 2.4e-102 343.1 25.7 2.8e-102 342.9 25.7 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel Anoct_dimer PF16178.5 OQR90553.1 - 1.8e-07 31.1 0.0 3.1e-07 30.3 0.0 1.3 1 0 0 1 1 1 1 Dimerisation domain of Ca+-activated chloride-channel, anoctamin DUF2207 PF09972.9 OQR90553.1 - 9.1 4.9 12.6 3.4 6.3 3.4 2.5 2 1 0 2 2 2 0 Predicted membrane protein (DUF2207) TauE PF01925.19 OQR90557.1 - 0.02 14.5 3.1 0.025 14.2 3.1 1.1 1 0 0 1 1 1 0 Sulfite exporter TauE/SafE zf-C3HC4_3 PF13920.6 OQR90558.1 - 5.3e-14 51.8 9.7 9.9e-14 50.9 9.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) PH PF00169.29 OQR90558.1 - 2.9e-08 34.2 0.3 4.6e-08 33.5 0.3 1.3 1 0 0 1 1 1 1 PH domain zf-RING_2 PF13639.6 OQR90558.1 - 4e-06 27.1 10.2 1.1e-05 25.7 10.2 1.8 1 0 0 1 1 1 1 Ring finger domain Prok-RING_4 PF14447.6 OQR90558.1 - 5.5e-06 26.1 9.6 1.3e-05 25.0 9.6 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 OQR90558.1 - 2e-05 24.4 11.3 3.6e-05 23.5 11.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) PH_11 PF15413.6 OQR90558.1 - 0.00013 22.3 0.4 0.00024 21.5 0.4 1.4 1 0 0 1 1 1 1 Pleckstrin homology domain Ank_2 PF12796.7 OQR90558.1 - 0.00055 20.5 1.2 0.0025 18.4 0.4 2.1 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) zf-RING_5 PF14634.6 OQR90558.1 - 0.0013 18.7 9.1 0.0013 18.7 9.1 2.0 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4 PF00097.25 OQR90558.1 - 0.0014 18.4 10.4 0.0032 17.3 10.4 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-P11 PF03854.14 OQR90558.1 - 0.0033 17.1 10.5 0.0033 17.1 10.5 2.8 3 1 1 4 4 3 1 P-11 zinc finger Ank_5 PF13857.6 OQR90558.1 - 0.0095 16.2 2.0 0.026 14.8 1.2 2.2 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 OQR90558.1 - 0.14 12.8 2.7 2 9.1 0.1 3.0 3 1 0 3 3 3 0 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQR90558.1 - 0.14 12.8 2.3 0.44 11.3 0.4 2.8 3 0 0 3 3 2 0 Ankyrin repeat DZR PF12773.7 OQR90558.1 - 1.3 9.1 6.5 1.3 9.1 1.2 2.4 2 0 0 2 2 2 0 Double zinc ribbon zf-C3HC4_4 PF15227.6 OQR90558.1 - 1.6 8.9 10.0 4.5 7.5 10.1 1.8 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING RecR PF02132.15 OQR90558.1 - 4.5 6.9 9.4 1.5 8.5 4.2 2.4 1 1 1 2 2 2 0 RecR protein RPN7 PF10602.9 OQR90561.1 - 6.5e-53 179.0 2.9 1.3e-52 178.0 2.9 1.5 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.27 OQR90561.1 - 1.2e-15 57.9 0.3 7.3e-15 55.4 0.0 2.2 2 0 0 2 2 2 1 PCI domain TPR_2 PF07719.17 OQR90561.1 - 0.0043 17.1 0.4 3.8 7.8 0.1 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat HGD-D PF06050.13 OQR90561.1 - 0.095 12.4 0.8 0.19 11.4 0.5 1.6 2 0 0 2 2 2 0 2-hydroxyglutaryl-CoA dehydratase, D-component HSCB_C PF07743.13 OQR90561.1 - 0.099 13.1 4.7 0.06 13.8 1.8 2.1 2 0 0 2 2 2 0 HSCB C-terminal oligomerisation domain Ank_2 PF12796.7 OQR90562.1 - 1.6e-46 156.8 17.5 1.2e-13 51.5 0.7 4.9 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQR90562.1 - 1.2e-35 121.4 0.9 5.7e-11 42.7 0.1 4.7 3 1 2 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQR90562.1 - 1.5e-30 101.8 6.9 0.00043 20.5 0.0 8.6 8 0 0 8 8 8 7 Ankyrin repeat Ank PF00023.30 OQR90562.1 - 1.4e-28 98.0 12.0 0.00012 22.3 0.3 8.2 7 1 1 8 8 8 6 Ankyrin repeat Ank_5 PF13857.6 OQR90562.1 - 8.8e-21 73.7 13.5 7.3e-06 26.2 0.2 7.3 2 2 6 8 8 8 6 Ankyrin repeats (many copies) Pkinase PF00069.25 OQR90563.1 - 1.8e-16 60.3 0.0 4.9e-16 58.9 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQR90563.1 - 5.9e-13 48.7 0.0 9.2e-13 48.1 0.0 1.4 2 0 0 2 2 2 1 Protein tyrosine kinase Ank_2 PF12796.7 OQR90564.1 - 4.8e-41 139.2 2.1 9.4e-12 45.4 0.0 3.0 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.30 OQR90564.1 - 7e-28 95.8 0.2 8.5e-06 26.0 0.0 4.1 4 0 0 4 4 4 4 Ankyrin repeat Ank_3 PF13606.6 OQR90564.1 - 2.6e-23 79.6 0.1 9.3e-05 22.6 0.0 4.2 4 0 0 4 4 4 4 Ankyrin repeat Ank_5 PF13857.6 OQR90564.1 - 3.1e-23 81.5 0.1 7.1e-08 32.6 0.0 3.4 2 2 1 3 3 3 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 OQR90564.1 - 2.3e-22 79.1 0.1 3.3e-11 43.5 0.0 2.4 2 0 0 2 2 2 2 Ankyrin repeats (many copies) SLBP_RNA_bind PF15247.6 OQR90566.1 - 6.1e-32 109.6 1.7 2.1e-31 107.8 1.7 1.9 1 0 0 1 1 1 1 Histone RNA hairpin-binding protein RNA-binding domain Ten1_2 PF15490.6 OQR90567.1 - 1.6e-27 95.6 0.2 1.7e-27 95.4 0.2 1.0 1 0 0 1 1 1 1 Telomere-capping, CST complex subunit Rep_fac-A_3 PF08661.11 OQR90567.1 - 0.00018 21.8 0.0 0.00021 21.6 0.0 1.1 1 0 0 1 1 1 1 Replication factor A protein 3 DUF4688 PF15752.5 OQR90567.1 - 0.044 13.0 0.0 0.047 12.9 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4688) DUF3573 PF12097.8 OQR90568.1 - 0.26 10.1 1.4 0.31 9.8 0.5 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3573) HAUS6_N PF14661.6 OQR90568.1 - 0.38 10.3 3.7 0.64 9.6 3.7 1.3 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus V_ATPase_I PF01496.19 OQR90568.1 - 0.46 8.4 4.0 0.58 8.0 4.0 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DivIC PF04977.15 OQR90568.1 - 2.5 7.9 6.4 0.15 11.9 0.4 2.1 2 1 0 2 2 2 0 Septum formation initiator Trypsin_2 PF13365.6 OQR90569.1 - 0.054 14.4 0.1 0.1 13.5 0.1 1.6 1 1 0 1 1 1 0 Trypsin-like peptidase domain Elicitin PF00964.17 OQR90570.1 - 1.8e-07 31.2 13.9 0.0017 18.4 3.8 2.8 2 0 0 2 2 2 2 Elicitin zf-C2HC_2 PF13913.6 OQR90570.1 - 0.0018 18.1 20.9 0.036 14.0 0.7 4.7 4 0 0 4 4 4 3 zinc-finger of a C2HC-type Tub PF01167.18 OQR90571.1 - 7.4e-42 143.8 0.0 1.5e-41 142.8 0.0 1.5 1 0 0 1 1 1 1 Tub family PDZ PF00595.24 OQR90571.1 - 0.034 14.5 0.0 0.068 13.5 0.0 1.5 1 0 0 1 1 1 0 PDZ domain DUF4519 PF15012.6 OQR90572.1 - 2.9 8.1 4.6 0.68 10.1 0.3 2.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4519) PNGaseA PF12222.8 OQR90575.1 - 3.4e-93 312.9 3.8 5e-93 312.3 3.8 1.2 1 0 0 1 1 1 1 Peptide N-acetyl-beta-D-glucosaminyl asparaginase amidase A Atrophin-1 PF03154.15 OQR90576.1 - 1.1 7.5 2.8 1.2 7.3 2.8 1.0 1 0 0 1 1 1 0 Atrophin-1 family Ring_hydroxyl_A PF00848.19 OQR90577.1 - 3.2e-36 125.3 0.1 6e-36 124.4 0.1 1.4 1 0 0 1 1 1 1 Ring hydroxylating alpha subunit (catalytic domain) Rieske PF00355.26 OQR90577.1 - 1.3e-14 53.9 0.0 2.3e-14 53.1 0.0 1.3 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain CCT PF06203.14 OQR90578.1 - 6.7e-18 64.5 9.8 1.1e-17 63.8 9.8 1.4 1 0 0 1 1 1 1 CCT motif CCT_2 PF09425.10 OQR90578.1 - 0.0022 17.9 0.2 0.0055 16.5 0.2 1.7 1 0 0 1 1 1 1 Divergent CCT motif SMC_N PF02463.19 OQR90579.1 - 6.1e-47 159.9 0.0 1.5e-38 132.4 0.0 4.0 3 2 1 4 4 4 2 RecF/RecN/SMC N terminal domain ABC_tran PF00005.27 OQR90579.1 - 3.6e-35 121.5 6.3 1e-28 100.6 0.0 4.3 4 1 0 4 4 3 3 ABC transporter ABC_membrane PF00664.23 OQR90579.1 - 6.7e-24 85.0 14.2 1.3e-23 84.0 14.2 1.4 1 0 0 1 1 1 1 ABC transporter transmembrane region AAA_23 PF13476.6 OQR90579.1 - 1.7e-18 67.9 16.9 2.6e-18 67.3 1.9 3.4 3 0 0 3 3 3 1 AAA domain AAA_15 PF13175.6 OQR90579.1 - 1e-10 41.9 11.7 3.5e-09 36.9 1.6 4.1 4 0 0 4 4 4 1 AAA ATPase domain AAA_21 PF13304.6 OQR90579.1 - 1.9e-10 41.0 4.0 2.4e-05 24.3 0.1 4.6 4 1 1 5 5 5 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 OQR90579.1 - 4.5e-10 39.1 0.3 3.9e-07 29.7 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 OQR90579.1 - 0.0013 18.8 0.7 0.34 11.0 0.0 3.6 2 1 1 3 3 3 1 50S ribosome-binding GTPase IstB_IS21 PF01695.17 OQR90579.1 - 0.0015 18.3 0.7 7.4 6.3 0.0 3.5 3 0 0 3 3 3 1 IstB-like ATP binding protein RsgA_GTPase PF03193.16 OQR90579.1 - 0.0016 18.3 0.0 3.1 7.7 0.0 3.0 3 0 0 3 3 2 2 RsgA GTPase AAA_27 PF13514.6 OQR90579.1 - 0.0018 17.9 0.1 0.006 16.2 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.14 OQR90579.1 - 0.0079 16.2 0.2 4.6 7.2 0.0 4.0 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 OQR90579.1 - 0.0084 16.4 0.3 25 5.1 0.0 3.9 3 0 0 3 3 3 0 AAA domain AAA PF00004.29 OQR90579.1 - 0.019 15.4 0.5 3.8 7.9 0.0 3.8 4 0 0 4 4 3 0 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 OQR90579.1 - 0.021 15.2 0.5 12 6.2 0.0 3.4 3 0 0 3 3 3 0 AAA ATPase domain RNA_helicase PF00910.22 OQR90579.1 - 0.062 13.7 0.2 3.9 7.9 0.0 3.5 3 0 0 3 3 3 0 RNA helicase AAA_18 PF13238.6 OQR90579.1 - 0.17 12.4 0.2 11 6.6 0.0 2.9 2 0 0 2 2 2 0 AAA domain CorA PF01544.18 OQR90579.1 - 0.35 10.1 4.8 0.53 9.5 3.3 2.0 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein DUF87 PF01935.17 OQR90579.1 - 0.36 10.9 6.5 0.62 10.1 0.3 3.7 3 0 0 3 3 3 0 Helicase HerA, central domain ABC_ATPase PF09818.9 OQR90579.1 - 0.65 8.7 5.0 2.5 6.8 0.0 3.0 3 0 0 3 3 3 0 Predicted ATPase of the ABC class DUF1319 PF07028.11 OQR90579.1 - 0.65 10.2 4.9 0.54 10.5 2.6 2.1 2 0 0 2 2 1 0 Protein of unknown function (DUF1319) MFS_1 PF07690.16 OQR90581.1 - 1e-08 34.5 28.8 1e-08 34.5 28.8 2.4 1 1 0 1 1 1 1 Major Facilitator Superfamily SPC25 PF06703.11 OQR90581.1 - 0.00028 20.7 1.0 0.00028 20.7 1.0 2.4 2 1 0 2 2 2 1 Microsomal signal peptidase 25 kDa subunit (SPC25) PetM PF08041.11 OQR90581.1 - 1.7 8.3 8.5 1.1 8.8 5.2 2.5 2 0 0 2 2 2 0 PetM family of cytochrome b6f complex subunit 7 F-box-like PF12937.7 OQR90588.1 - 6.1e-06 26.0 0.3 1.7e-05 24.6 0.3 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 OQR90588.1 - 0.027 14.3 0.2 0.027 14.3 0.2 2.2 2 0 0 2 2 2 0 F-box domain RabGAP-TBC PF00566.18 OQR90589.1 - 9.4e-33 113.7 0.9 9.4e-33 113.7 0.9 3.0 4 0 0 4 4 4 2 Rab-GTPase-TBC domain LPD34 PF18852.1 OQR90589.1 - 0.11 12.1 4.7 0.038 13.6 1.5 1.9 2 0 0 2 2 2 0 Large polyvalent protein associated domain 34 Topoisom_I_N PF02919.15 OQR90589.1 - 0.29 10.6 2.0 0.67 9.4 2.0 1.5 1 0 0 1 1 1 0 Eukaryotic DNA topoisomerase I, DNA binding fragment Takusan PF04822.13 OQR90589.1 - 1.2 9.0 5.9 3.7 7.5 0.2 3.4 2 1 1 3 3 3 0 Takusan Ank_2 PF12796.7 OQR90591.1 - 4.3e-09 36.8 1.0 1.5e-06 28.7 0.2 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQR90591.1 - 7.8e-09 35.9 2.1 0.00092 19.7 0.1 2.8 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 OQR90591.1 - 1.2e-06 28.7 1.0 0.087 13.2 0.2 3.7 1 1 3 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQR90591.1 - 1.7e-05 24.8 0.3 0.44 11.3 0.0 4.4 4 0 0 4 4 4 1 Ankyrin repeat 6PF2K PF01591.18 OQR90592.1 - 2.3e-72 242.9 0.0 3.2e-72 242.5 0.0 1.1 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 OQR90592.1 - 4.5e-25 88.5 0.0 2.6e-24 86.0 0.0 1.9 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.6 OQR90592.1 - 1.8e-07 31.4 0.0 3.4e-07 30.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.6 OQR90592.1 - 0.0032 17.9 0.0 0.0053 17.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.10 OQR90592.1 - 0.07 12.6 0.0 0.11 11.9 0.0 1.4 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA PF00004.29 OQR90592.1 - 0.079 13.4 0.0 0.17 12.3 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) SRP54 PF00448.22 OQR90592.1 - 0.1 12.2 0.0 0.98 9.0 0.0 2.1 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain HTH_25 PF13413.6 OQR90592.1 - 0.1 12.4 0.0 0.26 11.2 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain AAA_5 PF07728.14 OQR90592.1 - 0.14 12.2 0.0 0.24 11.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Zeta_toxin PF06414.12 OQR90592.1 - 0.15 11.3 0.0 0.52 9.6 0.0 2.0 1 1 0 1 1 1 0 Zeta toxin Pkinase PF00069.25 OQR90593.1 - 3.5e-54 183.9 0.0 5.1e-54 183.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQR90593.1 - 7.6e-32 110.6 0.0 1.1e-31 110.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 OQR90593.1 - 9.3e-09 34.9 0.1 5.6e-08 32.4 0.2 2.1 2 1 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 OQR90593.1 - 3.6e-06 26.5 0.0 5.1e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.22 OQR90593.1 - 8.1e-05 22.3 0.0 0.00016 21.3 0.0 1.4 1 0 0 1 1 1 1 RIO1 family RRM_1 PF00076.22 OQR90593.1 - 0.00017 21.3 0.1 0.001 18.8 0.0 2.3 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 OQR90593.1 - 0.013 15.7 0.0 0.025 14.7 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif APH PF01636.23 OQR90593.1 - 0.051 13.5 0.0 0.91 9.4 0.0 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.9 OQR90593.1 - 0.058 12.9 0.0 0.12 11.9 0.0 1.5 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Choline_kinase PF01633.20 OQR90593.1 - 0.076 12.6 0.0 0.14 11.7 0.0 1.5 1 0 0 1 1 1 0 Choline/ethanolamine kinase TPR_2 PF07719.17 OQR90594.1 - 8.8e-07 28.6 0.0 0.69 10.2 0.0 4.2 3 0 0 3 3 3 2 Tetratricopeptide repeat PHD PF00628.29 OQR90594.1 - 2.1e-06 27.5 10.2 5.6e-06 26.2 10.2 1.8 1 0 0 1 1 1 1 PHD-finger TPR_14 PF13428.6 OQR90594.1 - 4.3e-06 27.1 0.2 1.1 10.2 0.0 4.9 4 1 1 5 5 4 2 Tetratricopeptide repeat IQ PF00612.27 OQR90594.1 - 8.3e-06 25.2 27.6 0.00062 19.3 1.4 5.5 5 0 0 5 5 5 3 IQ calmodulin-binding motif TPR_19 PF14559.6 OQR90594.1 - 3.2e-05 24.3 0.2 0.88 10.1 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 OQR90594.1 - 4.8e-05 23.6 0.6 2.3 8.6 0.0 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.28 OQR90594.1 - 0.00078 19.2 0.0 5.4 7.0 0.0 3.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 OQR90594.1 - 0.014 15.6 0.1 0.072 13.3 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_9 PF13371.6 OQR90594.1 - 0.025 14.7 0.0 0.11 12.7 0.0 2.2 1 0 0 1 1 1 0 Tetratricopeptide repeat Phe_ZIP PF08916.11 OQR90594.1 - 0.1 13.3 7.5 1.1 10.1 0.2 3.9 4 0 0 4 4 4 0 Phenylalanine zipper TPR_16 PF13432.6 OQR90594.1 - 0.17 12.6 1.6 4 8.2 0.0 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.6 OQR90594.1 - 0.79 10.5 3.3 58 4.6 0.0 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat Cpn10 PF00166.21 OQR90596.1 - 2.8e-28 97.8 0.0 3.1e-28 97.7 0.0 1.0 1 0 0 1 1 1 1 Chaperonin 10 Kd subunit Glyco_hydro_3 PF00933.21 OQR90597.1 - 8e-57 193.0 0.0 1.1e-56 192.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.22 OQR90597.1 - 5.6e-36 124.4 0.0 1.1e-35 123.5 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.6 OQR90597.1 - 6.6e-11 42.2 0.0 1.4e-10 41.1 0.0 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain CRAL_TRIO PF00650.20 OQR90598.1 - 2.6e-26 92.3 0.1 3.3e-26 91.9 0.1 1.1 1 0 0 1 1 1 1 CRAL/TRIO domain HEAT_2 PF13646.6 OQR90599.1 - 3.8e-32 110.5 2.3 3.2e-13 49.9 0.0 3.2 2 1 1 3 3 3 3 HEAT repeats HEAT_PBS PF03130.16 OQR90599.1 - 2e-22 77.5 0.1 2e-05 24.8 0.0 5.9 6 0 0 6 6 6 4 PBS lyase HEAT-like repeat HEAT PF02985.22 OQR90599.1 - 4e-09 36.0 0.2 0.45 10.9 0.0 5.7 6 0 0 6 6 6 3 HEAT repeat HEAT_EZ PF13513.6 OQR90599.1 - 0.0031 18.0 0.5 1.3 9.6 0.1 3.7 3 1 1 4 4 4 2 HEAT-like repeat DUF533 PF04391.12 OQR90599.1 - 0.013 15.1 0.3 0.31 10.6 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF533) DUF1955 PF09205.10 OQR90599.1 - 0.07 12.9 0.1 0.21 11.3 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1955) Aminotran_1_2 PF00155.21 OQR90600.1 - 1.1e-40 140.0 0.0 1.5e-40 139.5 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II DapB_C PF05173.14 OQR90600.1 - 1.7e-28 99.1 0.1 5.2e-28 97.5 0.0 1.9 2 0 0 2 2 2 1 Dihydrodipicolinate reductase, C-terminus DapB_N PF01113.20 OQR90600.1 - 4e-10 39.9 0.0 4.6e-08 33.2 0.0 2.5 1 1 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus Aminotran_MocR PF12897.7 OQR90600.1 - 3.9e-09 35.8 0.0 3.4e-08 32.7 0.0 2.2 1 1 0 1 1 1 1 Alanine-glyoxylate amino-transferase Chlam_vir PF05475.11 OQR90600.1 - 0.016 15.0 0.0 2.3 7.9 0.0 2.9 3 0 0 3 3 3 0 Pgp3 C-terminal domain Beta_elim_lyase PF01212.21 OQR90600.1 - 0.067 12.5 0.0 0.12 11.6 0.0 1.3 1 0 0 1 1 1 0 Beta-eliminating lyase Nic96 PF04097.14 OQR90612.1 - 2.2e-54 185.0 0.3 7.9e-54 183.2 0.3 1.9 1 1 0 1 1 1 1 Nup93/Nic96 FCP1_C PF09309.10 OQR90612.1 - 0.012 15.6 0.2 0.023 14.6 0.2 1.4 1 0 0 1 1 1 0 FCP1, C-terminal Ank_2 PF12796.7 OQR90613.1 - 2e-26 92.3 0.4 6.7e-08 33.0 0.0 4.0 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OQR90613.1 - 2.7e-25 88.1 2.0 2.3e-07 31.0 0.1 4.7 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 OQR90613.1 - 5.1e-18 65.2 0.4 0.00053 20.5 0.0 5.3 2 2 2 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 OQR90613.1 - 4.8e-16 58.4 0.8 0.00015 22.1 0.1 6.0 5 0 0 5 5 5 2 Ankyrin repeat Ank_3 PF13606.6 OQR90613.1 - 7.5e-15 53.6 0.4 0.026 15.0 0.0 5.9 5 0 0 5 5 4 3 Ankyrin repeat zf-C3HC4 PF00097.25 OQR90613.1 - 4e-09 36.2 6.4 4e-09 36.2 6.4 2.4 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 OQR90613.1 - 2.1e-08 33.9 8.7 9.8e-08 31.7 8.7 2.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 OQR90613.1 - 1.2e-07 32.0 8.9 1.2e-07 32.0 8.9 2.6 2 0 0 2 2 1 1 Ring finger domain zf-RING_UBOX PF13445.6 OQR90613.1 - 4.3e-06 26.7 4.7 4.3e-06 26.7 4.7 2.2 2 0 0 2 2 1 1 RING-type zinc-finger zf-ANAPC11 PF12861.7 OQR90613.1 - 0.00043 20.3 3.6 0.00058 19.9 2.0 2.1 2 0 0 2 2 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.6 OQR90613.1 - 0.0011 18.7 7.8 0.0011 18.7 7.8 3.0 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 OQR90613.1 - 0.0014 18.8 7.3 0.0014 18.8 7.3 3.0 3 0 0 3 3 2 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.7 OQR90613.1 - 0.0021 18.3 5.8 0.0021 18.3 5.8 2.5 2 0 0 2 2 1 1 RING-H2 zinc finger domain PWI PF01480.17 OQR90613.1 - 0.024 14.9 0.0 0.11 12.8 0.0 2.2 1 0 0 1 1 1 0 PWI domain zf-Nse PF11789.8 OQR90613.1 - 0.032 14.0 3.4 0.098 12.5 3.4 1.9 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit YscO PF07321.12 OQR90613.1 - 0.73 9.8 7.0 2.4 8.1 0.8 2.5 2 0 0 2 2 2 0 Type III secretion protein YscO Baculo_PEP_C PF04513.12 OQR90613.1 - 0.77 9.8 29.6 0.017 15.1 2.9 4.0 4 0 0 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1664 PF07889.12 OQR90613.1 - 1.5 8.9 3.9 3.7 7.6 0.1 2.9 3 0 0 3 3 2 0 Protein of unknown function (DUF1664) DUF1387 PF07139.11 OQR90613.1 - 3.7 7.2 13.1 9 5.9 13.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) AA_permease_2 PF13520.6 OQR90633.1 - 1.9e-07 30.3 27.9 1.9e-07 30.3 27.9 2.4 2 1 0 2 2 2 1 Amino acid permease AA_permease PF00324.21 OQR90633.1 - 3.9e-06 25.7 23.2 3.9e-06 25.7 23.2 2.4 2 0 0 2 2 2 1 Amino acid permease MFS_1 PF07690.16 OQR90641.1 - 0.0011 18.0 34.4 0.0038 16.2 26.4 3.5 1 1 2 3 3 3 3 Major Facilitator Superfamily PTPLA PF04387.14 OQR90642.1 - 1.3e-56 190.8 7.9 1.3e-56 190.8 7.9 3.5 4 0 0 4 4 4 1 Protein tyrosine phosphatase-like protein, PTPLA RGS_DHEX PF18148.1 OQR90642.1 - 0.19 11.9 0.4 2.1 8.5 0.0 2.4 2 0 0 2 2 2 0 Regulator of G-protein signalling DHEX domain DUF5531 PF17671.1 OQR90642.1 - 0.66 9.8 4.6 14 5.5 0.5 2.8 2 0 0 2 2 2 0 Family of unknown function (DUF5531) Med26 PF08711.11 OQR90643.1 - 8.2e-11 41.8 0.0 1.9e-10 40.6 0.0 1.6 1 0 0 1 1 1 1 TFIIS helical bundle-like domain PAP2 PF01569.21 OQR90643.1 - 6.1e-09 35.8 4.5 6.1e-09 35.8 4.5 2.1 2 1 1 3 3 3 1 PAP2 superfamily ABC_tran PF00005.27 OQR90655.1 - 8e-12 45.8 0.0 1.2e-11 45.3 0.0 1.3 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 OQR90655.1 - 0.0008 18.9 0.1 0.00095 18.7 0.1 1.1 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain ABC_ATPase PF09818.9 OQR90655.1 - 0.0036 16.2 0.1 0.0042 15.9 0.1 1.3 1 1 0 1 1 1 1 Predicted ATPase of the ABC class SbcCD_C PF13558.6 OQR90655.1 - 0.006 16.8 1.5 0.33 11.2 1.3 2.6 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA PF00004.29 OQR90655.1 - 0.078 13.4 0.1 0.095 13.1 0.1 1.2 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PIP5K PF01504.18 OQR90656.1 - 9.5e-69 231.7 0.3 5.5e-68 229.2 0.3 2.0 1 1 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase 7tm_2 PF00002.24 OQR90656.1 - 1.9e-07 30.7 1.2 1.9e-07 30.7 1.2 2.4 2 1 0 2 2 2 1 7 transmembrane receptor (Secretin family) DoxX_2 PF13564.6 OQR90656.1 - 0.023 14.8 0.0 0.064 13.4 0.0 1.7 1 0 0 1 1 1 0 DoxX-like family Adeno_E3B PF03376.14 OQR90656.1 - 0.033 14.4 0.9 0.033 14.4 0.9 2.2 2 0 0 2 2 2 0 Adenovirus E3B protein AstA PF04958.12 OQR90656.1 - 0.15 10.6 0.0 0.26 9.8 0.0 1.3 1 0 0 1 1 1 0 Arginine N-succinyltransferase beta subunit DUF5058 PF16481.5 OQR90656.1 - 0.41 10.3 3.0 17 5.0 0.4 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF5058) Yip1 PF04893.17 OQR90656.1 - 2.6 7.8 13.1 0.32 10.7 2.5 2.7 3 0 0 3 3 3 0 Yip1 domain CaMKII_AD PF08332.10 OQR90657.1 - 9e-11 42.0 0.1 1e-10 41.8 0.1 1.1 1 0 0 1 1 1 1 Calcium/calmodulin dependent protein kinase II association domain SnoaL_3 PF13474.6 OQR90657.1 - 0.0017 18.6 0.1 0.0017 18.6 0.1 1.0 1 0 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.6 OQR90657.1 - 0.009 16.4 0.0 0.0096 16.3 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) PX PF00787.24 OQR90658.1 - 7.8e-09 35.5 0.0 1.4e-08 34.7 0.0 1.4 1 0 0 1 1 1 1 PX domain adh_short_C2 PF13561.6 OQR90659.1 - 4.3e-53 180.3 0.7 5.2e-53 180.0 0.7 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OQR90659.1 - 7.3e-44 149.6 1.4 9.7e-44 149.2 1.4 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OQR90659.1 - 1e-12 48.4 2.1 1.2e-12 48.1 0.7 1.7 2 0 0 2 2 2 1 KR domain F420_oxidored PF03807.17 OQR90659.1 - 0.0017 18.9 0.1 0.0044 17.6 0.1 1.7 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent DeoC PF01791.9 OQR90659.1 - 0.04 13.5 0.0 0.065 12.8 0.0 1.3 1 0 0 1 1 1 0 DeoC/LacD family aldolase DNA_pol_A_exoN PF18305.1 OQR90660.1 - 0.023 15.0 0.4 11 6.3 0.0 2.8 3 0 0 3 3 3 0 3' to 5' exonuclease C-terminal domain P53 PF00870.18 OQR90660.1 - 0.12 12.2 0.0 0.19 11.5 0.0 1.3 1 0 0 1 1 1 0 P53 DNA-binding domain UNC-93 PF05978.16 OQR90670.1 - 2.4e-10 40.4 7.3 2.4e-10 40.4 7.3 3.0 3 0 0 3 3 3 1 Ion channel regulatory protein UNC-93 MFS_1 PF07690.16 OQR90670.1 - 5.6e-10 38.7 35.2 5.6e-10 38.7 35.2 2.7 2 2 1 3 3 3 1 Major Facilitator Superfamily CRAL_TRIO PF00650.20 OQR90671.1 - 3e-32 111.5 0.4 4.3e-32 111.0 0.4 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 OQR90671.1 - 0.00017 21.8 0.1 0.00031 20.9 0.1 1.4 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain CarD_CdnL_TRCF PF02559.16 OQR90671.1 - 0.008 16.9 0.4 3.4 8.5 0.0 2.8 1 1 2 3 3 3 2 CarD-like/TRCF domain CRAL_TRIO_N PF03765.15 OQR90671.1 - 0.028 14.6 0.0 0.082 13.1 0.0 1.8 2 0 0 2 2 2 0 CRAL/TRIO, N-terminal domain YEATS PF03366.16 OQR90671.1 - 0.098 12.6 0.1 0.29 11.1 0.1 1.8 1 1 0 1 1 1 0 YEATS family Pkinase PF00069.25 OQR90672.1 - 1.6e-09 37.5 1.4 3.7e-07 29.8 0.3 2.1 1 1 1 2 2 2 2 Protein kinase domain Pkinase_fungal PF17667.1 OQR90672.1 - 9.1e-07 28.0 0.2 1.1e-06 27.7 0.2 1.1 1 0 0 1 1 1 1 Fungal protein kinase Pkinase_Tyr PF07714.17 OQR90672.1 - 0.00037 19.9 1.0 0.15 11.3 0.4 2.5 1 1 1 2 2 2 2 Protein tyrosine kinase Kdo PF06293.14 OQR90672.1 - 0.0044 16.4 0.1 0.0054 16.1 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family DUF4474 PF14751.6 OQR90672.1 - 0.12 11.8 0.0 0.13 11.6 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4474) Syntaxin-18_N PF10496.9 OQR90673.1 - 0.097 12.9 1.3 0.2 12.0 1.3 1.5 1 0 0 1 1 1 0 SNARE-complex protein Syntaxin-18 N-terminus NINJA_B PF16136.5 OQR90673.1 - 0.29 11.5 7.0 0.48 10.8 7.0 1.3 1 0 0 1 1 1 0 Putative nuclear localisation signal PDZ_6 PF17820.1 OQR90676.1 - 8.8e-15 54.3 0.0 0.0034 17.2 0.0 4.7 5 0 0 5 5 5 4 PDZ domain PDZ PF00595.24 OQR90676.1 - 1.6e-12 47.6 0.0 0.07 13.5 0.0 5.8 6 0 0 6 6 6 4 PDZ domain PDZ_2 PF13180.6 OQR90676.1 - 0.00014 22.1 0.0 0.089 13.1 0.0 3.9 4 0 0 4 4 4 1 PDZ domain SOG2 PF10428.9 OQR90676.1 - 5.2 6.2 22.2 9.7 5.3 22.2 1.4 1 0 0 1 1 1 0 RAM signalling pathway protein Ank_2 PF12796.7 OQR90677.1 - 4.7e-77 254.6 42.4 3.2e-11 43.7 0.1 14.5 10 6 3 13 13 13 11 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQR90677.1 - 2.5e-61 203.3 29.6 1.4e-07 31.9 0.0 18.0 15 6 6 21 21 21 13 Ankyrin repeats (many copies) Ank_5 PF13857.6 OQR90677.1 - 7.5e-56 185.5 38.6 9.4e-06 25.8 2.0 17.8 14 3 6 20 20 20 13 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQR90677.1 - 1.3e-47 154.2 33.0 0.017 15.6 0.0 22.0 22 1 0 22 22 22 12 Ankyrin repeat Ank PF00023.30 OQR90677.1 - 1.5e-43 145.4 49.8 0.0019 18.6 0.1 20.9 23 0 0 23 23 23 11 Ankyrin repeat WD40 PF00400.32 OQR90679.1 - 2.8e-28 97.6 13.4 1.1e-07 32.4 0.2 5.9 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OQR90679.1 - 5e-16 58.8 2.2 0.00078 19.7 0.0 5.1 2 1 4 6 6 6 6 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 OQR90679.1 - 3e-06 27.3 0.0 0.00014 21.9 0.0 2.6 1 1 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 OQR90679.1 - 9.5e-06 24.8 0.1 0.004 16.1 0.0 3.2 2 1 0 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Gmad1 PF10647.9 OQR90679.1 - 0.00057 19.7 0.3 1.2 8.8 0.0 3.2 2 1 1 3 3 3 2 Lipoprotein LpqB beta-propeller domain PD40 PF07676.12 OQR90679.1 - 0.0064 16.4 0.5 0.34 10.9 0.1 2.9 3 0 0 3 3 3 1 WD40-like Beta Propeller Repeat Ndufs5 PF10200.9 OQR90680.1 - 0.00013 22.2 0.2 0.00017 21.8 0.2 1.2 1 0 0 1 1 1 1 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa DUF3128 PF11326.8 OQR90680.1 - 0.029 14.7 2.6 0.15 12.4 2.6 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3128) UPF0203 PF05254.12 OQR90680.1 - 0.9 9.8 4.9 5.8 7.2 4.9 1.9 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0203) TMEM132D_C PF15706.5 OQR90688.1 - 0.097 12.5 0.0 3 7.7 0.0 2.1 2 0 0 2 2 2 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term zf-PARP PF00645.18 OQR90689.1 - 1.4e-06 29.0 1.8 9.1e-06 26.5 1.8 2.0 1 1 0 1 1 1 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region Ion_trans_2 PF07885.16 OQR90698.1 - 5.5e-10 39.1 6.1 1.5e-09 37.6 6.1 1.8 1 0 0 1 1 1 1 Ion channel Ion_trans PF00520.31 OQR90698.1 - 0.0026 17.0 12.2 0.0026 17.0 12.2 1.9 2 1 0 2 2 2 1 Ion transport protein IRK PF01007.20 OQR90698.1 - 0.055 13.3 1.5 0.37 10.6 0.4 2.3 2 0 0 2 2 2 0 Inward rectifier potassium channel transmembrane domain HSCB_C PF07743.13 OQR90699.1 - 3.8e-17 62.6 0.3 7.7e-17 61.6 0.3 1.5 1 0 0 1 1 1 1 HSCB C-terminal oligomerisation domain DnaJ PF00226.31 OQR90699.1 - 2.1e-07 31.0 0.1 4.3e-07 29.9 0.1 1.5 1 0 0 1 1 1 1 DnaJ domain Nucleo_LEF-12 PF06256.11 OQR90699.1 - 0.12 12.1 0.7 0.19 11.5 0.7 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus LEF-12 protein Pepdidase_M14_N PF18027.1 OQR90700.1 - 3.2e-10 40.3 0.1 7.1e-10 39.2 0.1 1.6 1 0 0 1 1 1 1 Cytosolic carboxypeptidase N-terminal domain Peptidase_M14 PF00246.24 OQR90700.1 - 1.3e-08 35.0 0.0 3.2e-08 33.7 0.0 1.6 1 1 0 1 1 1 1 Zinc carboxypeptidase Arm PF00514.23 OQR90700.1 - 0.00047 20.1 5.2 0.26 11.4 0.0 5.8 6 0 0 6 6 6 1 Armadillo/beta-catenin-like repeat AstE_AspA PF04952.14 OQR90700.1 - 0.0022 17.1 0.0 0.0041 16.2 0.0 1.4 1 0 0 1 1 1 1 Succinylglutamate desuccinylase / Aspartoacylase family RIH_assoc PF08454.11 OQR90700.1 - 0.042 13.7 0.1 0.23 11.3 0.1 2.3 1 0 0 1 1 1 0 RyR and IP3R Homology associated Atx10homo_assoc PF09759.9 OQR90700.1 - 0.16 12.1 0.1 1.4 9.0 0.0 2.6 2 0 0 2 2 2 0 Spinocerebellar ataxia type 10 protein domain Pribosyltran PF00156.27 OQR90701.1 - 4e-13 49.2 0.0 5e-13 48.9 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 OQR90701.1 - 0.00014 21.3 0.0 0.00018 21.0 0.0 1.1 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase TTc_toxin_rep PF18807.1 OQR90702.1 - 0.11 12.3 0.5 1.2 9.0 0.5 2.2 2 0 0 2 2 2 0 Tripartite Tc toxins repeat Hist_deacetyl PF00850.19 OQR90703.1 - 4.8e-69 233.2 0.1 9.4e-69 232.2 0.0 1.4 2 0 0 2 2 2 1 Histone deacetylase domain Ank_2 PF12796.7 OQR90703.1 - 6.5e-14 52.3 0.1 2.9e-10 40.6 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQR90703.1 - 6.2e-12 45.8 0.0 5e-09 36.5 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 OQR90703.1 - 1.2e-11 44.6 0.1 0.00056 20.2 0.0 3.6 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQR90703.1 - 5.1e-11 41.8 0.8 0.01 16.3 0.0 4.7 4 0 0 4 4 4 2 Ankyrin repeat Ank PF00023.30 OQR90703.1 - 2.5e-10 40.3 4.0 0.00049 20.4 0.0 4.6 4 0 0 4 4 4 3 Ankyrin repeat Pkinase PF00069.25 OQR90704.1 - 4.1e-63 213.2 0.0 3.4e-62 210.2 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQR90704.1 - 3e-33 115.2 0.0 4e-33 114.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OQR90704.1 - 5.1e-06 26.0 0.1 2.5e-05 23.8 0.0 2.0 2 1 0 2 2 2 1 Kinase-like YrbL-PhoP_reg PF10707.9 OQR90704.1 - 0.00012 21.7 0.2 0.00027 20.5 0.2 1.6 1 1 0 1 1 1 1 PhoP regulatory network protein YrbL Pkinase_fungal PF17667.1 OQR90704.1 - 0.00021 20.2 0.0 0.00032 19.6 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 OQR90704.1 - 0.00088 18.7 0.1 0.0013 18.1 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pox_ser-thr_kin PF05445.11 OQR90704.1 - 0.0036 16.3 0.0 0.0056 15.7 0.0 1.2 1 0 0 1 1 1 1 Poxvirus serine/threonine protein kinase APH PF01636.23 OQR90704.1 - 0.013 15.4 0.1 0.099 12.5 0.0 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family NAD_Gly3P_dh_N PF01210.23 OQR90704.1 - 0.14 12.1 0.1 0.29 11.1 0.1 1.5 1 1 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus HypA PF01155.19 OQR90705.1 - 0.051 13.6 0.3 0.064 13.3 0.3 1.2 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA CTU2 PF10288.9 OQR90705.1 - 0.14 12.4 3.4 0.17 12.2 3.4 1.1 1 0 0 1 1 1 0 Cytoplasmic tRNA 2-thiolation protein 2 Eapp_C PF10238.9 OQR90705.1 - 0.15 12.1 4.3 0.054 13.6 2.0 1.3 1 1 0 1 1 1 0 E2F-associated phosphoprotein Laminin_G_3 PF13385.6 OQR90707.1 - 1.2e-15 58.0 5.6 1.7e-09 38.0 0.1 3.7 3 0 0 3 3 3 2 Concanavalin A-like lectin/glucanases superfamily CUB PF00431.20 OQR90707.1 - 1.2e-08 35.3 0.0 0.064 13.6 0.0 4.1 3 0 0 3 3 3 3 CUB domain EGF_2 PF07974.13 OQR90707.1 - 0.014 15.8 12.9 0.014 15.8 12.9 3.9 4 0 0 4 4 4 0 EGF-like domain Lpp-LpqN PF10738.9 OQR90707.1 - 0.032 13.7 0.0 0.073 12.5 0.0 1.6 1 0 0 1 1 1 0 Probable lipoprotein LpqN CUB PF00431.20 OQR90708.1 - 4e-06 27.1 0.0 0.00014 22.2 0.0 3.0 2 0 0 2 2 2 1 CUB domain Ephrin_rec_like PF07699.13 OQR90708.1 - 0.0048 16.6 3.9 0.0048 16.6 3.9 3.2 2 0 0 2 2 2 1 Putative ephrin-receptor like EGF_2 PF07974.13 OQR90708.1 - 0.0073 16.7 14.1 0.0073 16.7 14.1 3.4 4 0 0 4 4 4 1 EGF-like domain EGF_Tenascin PF18720.1 OQR90708.1 - 0.013 15.5 13.8 0.068 13.2 13.8 2.4 1 0 0 1 1 1 0 Tenascin EGF domain NCD3G PF07562.14 OQR90708.1 - 0.044 13.7 12.0 0.23 11.4 2.6 2.8 2 0 0 2 2 2 0 Nine Cysteines Domain of family 3 GPCR Glyco_hydro_2_C PF02836.17 OQR90708.1 - 0.062 12.4 0.1 0.11 11.6 0.1 1.2 1 0 0 1 1 1 0 Glycosyl hydrolases family 2, TIM barrel domain Prp18 PF02840.15 OQR90710.1 - 3.5e-15 56.3 0.2 2.6e-14 53.5 0.0 2.1 2 0 0 2 2 2 1 Prp18 domain SHIPPO-rpt PF07004.12 OQR90710.1 - 0.013 16.4 8.0 0.4 11.7 0.1 5.0 4 1 0 4 4 4 0 Sperm-tail PG-rich repeat V-ATPase_G_2 PF16999.5 OQR90710.1 - 0.18 12.3 1.3 2 8.9 0.4 2.3 2 0 0 2 2 2 0 Vacuolar (H+)-ATPase G subunit Adaptin_N PF01602.20 OQR90711.1 - 9.7e-112 374.2 16.6 1.3e-111 373.8 16.6 1.1 1 0 0 1 1 1 1 Adaptin N terminal region COP-gamma_platf PF08752.10 OQR90711.1 - 1.6e-48 164.7 0.3 6.2e-48 162.8 0.2 2.1 2 0 0 2 2 2 1 Coatomer gamma subunit appendage platform subdomain HEAT_2 PF13646.6 OQR90711.1 - 3.3e-16 59.4 5.5 3.2e-06 27.4 0.0 6.1 3 2 4 7 7 7 4 HEAT repeats Cnd1 PF12717.7 OQR90711.1 - 7e-15 55.4 16.6 2.7e-08 34.0 1.7 4.1 3 1 1 4 4 4 3 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 OQR90711.1 - 2.3e-05 24.2 9.2 14 6.3 0.1 7.2 6 0 0 6 6 6 2 HEAT repeat HEAT_EZ PF13513.6 OQR90711.1 - 0.00077 19.9 7.5 3.6 8.2 0.5 5.4 4 1 2 6 6 6 2 HEAT-like repeat Arm PF00514.23 OQR90711.1 - 0.013 15.5 1.5 13 6.0 0.0 4.9 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat ATPase PF06745.13 OQR90711.1 - 0.037 13.4 0.1 0.2 11.0 0.1 2.2 2 0 0 2 2 2 0 KaiC p450 PF00067.22 OQR90715.1 - 1.5e-80 271.2 0.0 1.8e-80 271.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF5464 PF17552.2 OQR90715.1 - 0.082 13.2 1.4 15 5.9 0.0 2.6 2 0 0 2 2 2 0 Family of unknown function (DUF5464) PGF-CTERM PF18204.1 OQR90716.1 - 0.26 11.3 0.6 0.26 11.3 0.6 2.6 3 1 0 3 3 3 0 PGF-CTERM motif ABC_tran PF00005.27 OQR90718.1 - 1.4e-51 174.6 0.0 4.3e-29 101.8 0.0 2.4 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 OQR90718.1 - 8.5e-51 173.2 35.0 1.3e-26 93.8 10.7 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region MMR_HSR1 PF01926.23 OQR90718.1 - 5.3e-07 29.7 0.1 0.044 13.9 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 OQR90718.1 - 7.9e-06 25.9 0.1 0.012 15.6 0.0 2.6 2 0 0 2 2 2 2 RsgA GTPase SMC_N PF02463.19 OQR90718.1 - 2.2e-05 24.0 5.8 0.36 10.2 0.1 4.1 2 2 1 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 OQR90718.1 - 0.00027 20.6 2.4 0.21 11.3 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 OQR90718.1 - 0.00045 20.7 0.1 0.46 10.9 0.0 2.9 2 0 0 2 2 2 1 AAA ATPase domain AAA_21 PF13304.6 OQR90718.1 - 0.00047 20.0 2.5 0.79 9.5 0.3 3.2 2 1 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 OQR90718.1 - 0.0014 18.9 0.2 2 8.7 0.1 3.1 2 1 0 2 2 2 1 AAA domain AAA_23 PF13476.6 OQR90718.1 - 0.0021 18.6 0.2 1.2 9.6 0.0 2.4 2 0 0 2 2 2 1 AAA domain Dynamin_N PF00350.23 OQR90718.1 - 0.0034 17.4 2.2 0.15 12.1 0.6 2.5 2 0 0 2 2 2 1 Dynamin family DUF815 PF05673.13 OQR90718.1 - 0.0036 16.5 0.1 3.2 6.8 0.1 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF815) AAA_18 PF13238.6 OQR90718.1 - 0.016 15.7 0.0 8.6 6.9 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 OQR90718.1 - 0.03 13.9 0.1 3.3 7.2 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region Roc PF08477.13 OQR90718.1 - 0.044 14.0 1.1 8.4 6.6 0.0 3.3 3 0 0 3 3 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_24 PF13479.6 OQR90718.1 - 0.061 13.0 0.0 0.83 9.3 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_15 PF13175.6 OQR90718.1 - 0.075 12.7 0.0 3.4 7.3 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain Ploopntkinase3 PF18751.1 OQR90718.1 - 0.11 12.4 0.0 4.2 7.2 0.0 2.4 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 Septin PF00735.18 OQR90718.1 - 0.13 11.6 0.1 3.2 7.0 0.0 2.3 2 0 0 2 2 2 0 Septin AAA_30 PF13604.6 OQR90718.1 - 0.15 11.8 0.6 22 4.7 0.0 2.8 2 1 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 OQR90718.1 - 0.15 11.3 2.2 0.75 9.0 0.1 2.6 3 0 0 3 3 2 0 Zeta toxin IstB_IS21 PF01695.17 OQR90718.1 - 0.15 11.8 1.7 12 5.6 0.1 3.1 3 0 0 3 3 3 0 IstB-like ATP binding protein ATP-synt_ab PF00006.25 OQR90718.1 - 0.16 11.6 0.0 11 5.6 0.0 2.6 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain NB-ARC PF00931.22 OQR90718.1 - 0.27 10.4 0.8 7.6 5.6 0.0 2.6 2 1 0 2 2 2 0 NB-ARC domain DUF87 PF01935.17 OQR90718.1 - 0.66 10.0 4.0 0.57 10.2 0.2 2.3 2 0 0 2 2 2 0 Helicase HerA, central domain DEAD PF00270.29 OQR90718.1 - 1.3 8.7 5.3 7.1 6.4 0.9 3.4 3 1 0 3 3 3 0 DEAD/DEAH box helicase Sterol_MT_C PF08498.10 OQR90719.1 - 1.1e-27 96.1 0.2 2.9e-27 94.7 0.2 1.8 1 0 0 1 1 1 1 Sterol methyltransferase C-terminal Methyltransf_11 PF08241.12 OQR90719.1 - 8.5e-21 74.4 0.0 1.9e-20 73.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OQR90719.1 - 2.1e-18 66.6 0.0 3.4e-18 65.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OQR90719.1 - 8.4e-18 64.9 0.0 1.9e-17 63.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 OQR90719.1 - 4.2e-17 62.3 0.0 6.7e-17 61.7 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.6 OQR90719.1 - 5.4e-15 55.6 0.0 8.1e-15 55.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 OQR90719.1 - 6.5e-11 42.0 0.0 1.7e-10 40.7 0.0 1.6 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 OQR90719.1 - 4.4e-09 37.0 0.0 9.1e-09 36.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 OQR90719.1 - 0.00052 19.5 0.0 0.00081 18.9 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 OQR90719.1 - 0.00083 18.9 0.0 0.0018 17.9 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_15 PF09445.10 OQR90719.1 - 0.0044 16.6 0.1 0.0084 15.7 0.1 1.5 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase PRE_C2HC PF07530.11 OQR90719.1 - 0.079 13.1 0.0 21 5.3 0.0 2.6 2 1 0 2 2 2 0 Associated with zinc fingers UPF0020 PF01170.18 OQR90719.1 - 0.12 12.1 0.0 0.65 9.7 0.0 1.9 2 0 0 2 2 2 0 Putative RNA methylase family UPF0020 NNMT_PNMT_TEMT PF01234.17 OQR90719.1 - 0.13 11.5 0.0 0.31 10.2 0.0 1.6 1 1 0 1 1 1 0 NNMT/PNMT/TEMT family Glyco_hydro_32N PF00251.20 OQR90722.1 - 1.5e-48 166.0 4.7 2.4e-48 165.3 4.7 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.12 OQR90722.1 - 2.5e-26 92.6 1.2 3.9e-26 91.9 1.2 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 C terminal DUF4975 PF16346.5 OQR90722.1 - 4.8e-05 23.5 0.5 0.00011 22.4 0.5 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4975) BNR_2 PF13088.6 OQR90722.1 - 0.00016 21.1 0.0 0.00032 20.1 0.0 1.5 1 0 0 1 1 1 1 BNR repeat-like domain Glyco_hydro_130 PF04041.13 OQR90722.1 - 0.029 13.3 0.0 0.05 12.5 0.0 1.3 1 0 0 1 1 1 0 beta-1,4-mannooligosaccharide phosphorylase BNR PF02012.20 OQR90722.1 - 0.073 13.1 1.1 0.66 10.2 0.6 3.1 2 0 0 2 2 2 0 BNR/Asp-box repeat Pro_Al_protease PF02983.14 OQR90722.1 - 0.33 11.1 2.5 10 6.3 0.2 2.4 2 0 0 2 2 2 0 Alpha-lytic protease prodomain SRAP PF02586.14 OQR90723.1 - 1.7e-58 197.8 0.1 2.9e-58 197.0 0.1 1.4 1 0 0 1 1 1 1 SOS response associated peptidase (SRAP) CBM_1 PF00734.18 OQR90724.1 - 3.5e-19 68.4 28.0 4.7e-12 45.6 12.1 4.7 6 0 0 6 6 6 2 Fungal cellulose binding domain Hydrolase_4 PF12146.8 OQR90725.1 - 6.9e-14 51.7 0.0 2.9e-10 39.8 0.0 2.2 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 OQR90725.1 - 1.2e-11 44.8 0.1 7.2e-09 35.7 0.1 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold AXE1 PF05448.12 OQR90725.1 - 4.9e-07 28.7 0.2 0.0043 15.8 0.0 2.3 1 1 1 2 2 2 2 Acetyl xylan esterase (AXE1) Abhydrolase_6 PF12697.7 OQR90725.1 - 2.4e-06 28.3 0.0 3.4e-06 27.8 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.18 OQR90725.1 - 8.9e-05 22.2 0.0 0.00038 20.1 0.0 1.9 1 1 1 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) Peptidase_S9 PF00326.21 OQR90725.1 - 0.00014 21.4 0.0 0.00033 20.2 0.0 1.6 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_2 PF02230.16 OQR90725.1 - 0.00085 19.2 0.1 0.07 12.9 0.1 3.0 2 1 0 2 2 2 1 Phospholipase/Carboxylesterase DLH PF01738.18 OQR90725.1 - 0.0027 17.3 0.0 0.03 13.9 0.0 2.3 2 1 0 2 2 2 1 Dienelactone hydrolase family DUF818 PF05677.12 OQR90725.1 - 0.017 14.1 0.0 0.025 13.5 0.0 1.2 1 0 0 1 1 1 0 Chlamydia CHLPS protein (DUF818) BAAT_C PF08840.11 OQR90725.1 - 0.13 12.2 0.0 2.4 8.0 0.0 2.2 1 1 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal Ras PF00071.22 OQR90736.1 - 5.5e-49 165.9 0.3 1.2e-48 164.8 0.3 1.6 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OQR90736.1 - 3.6e-33 114.3 0.3 1.4e-32 112.4 0.3 2.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OQR90736.1 - 7.4e-15 54.8 0.1 1.6e-14 53.8 0.1 1.5 1 0 0 1 1 1 1 ADP-ribosylation factor family Peptidase_M14 PF00246.24 OQR90736.1 - 1.6e-14 54.4 0.0 3.2e-14 53.4 0.0 1.5 1 0 0 1 1 1 1 Zinc carboxypeptidase Pepdidase_M14_N PF18027.1 OQR90736.1 - 4.2e-09 36.7 0.0 1.2e-08 35.2 0.0 1.8 1 0 0 1 1 1 1 Cytosolic carboxypeptidase N-terminal domain PPR PF01535.20 OQR90736.1 - 1.8e-06 27.8 0.1 1.3 9.5 0.0 5.8 4 0 0 4 4 4 2 PPR repeat Gtr1_RagA PF04670.12 OQR90736.1 - 6e-06 25.8 0.1 1.2e-05 24.8 0.1 1.5 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 OQR90736.1 - 0.00022 21.3 0.1 0.00055 20.0 0.1 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase PPR_2 PF13041.6 OQR90736.1 - 0.00026 21.1 0.3 18 5.6 0.0 4.8 5 0 0 5 5 3 0 PPR repeat family SRPRB PF09439.10 OQR90736.1 - 0.00029 20.3 0.1 0.001 18.6 0.0 1.9 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 OQR90736.1 - 0.00097 18.7 1.8 0.029 13.9 1.8 2.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AstE_AspA PF04952.14 OQR90736.1 - 0.01 14.9 0.0 0.017 14.2 0.0 1.3 1 0 0 1 1 1 0 Succinylglutamate desuccinylase / Aspartoacylase family PPR_3 PF13812.6 OQR90736.1 - 0.077 13.1 1.0 23 5.1 0.0 4.0 5 0 0 5 5 3 0 Pentatricopeptide repeat domain PPR_long PF17177.4 OQR90736.1 - 6.3 6.1 9.7 4.1 6.7 0.3 4.2 3 2 2 5 5 5 0 Pentacotripeptide-repeat region of PRORP Kinesin PF00225.23 OQR90737.1 - 1.2e-97 326.8 4.7 1.2e-97 326.8 4.7 1.8 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 OQR90737.1 - 2.4e-24 86.0 0.2 2.4e-24 86.0 0.2 2.6 2 1 1 3 3 3 1 Microtubule binding UPF0086 PF01868.16 OQR90737.1 - 0.036 14.0 0.4 0.23 11.4 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function UPF0086 RPW8 PF05659.11 OQR90737.1 - 0.23 11.2 4.0 0.17 11.5 0.4 2.4 2 1 0 2 2 2 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 XkdW PF09636.10 OQR90737.1 - 1.5 9.0 5.6 0.55 10.4 0.5 2.8 2 2 1 3 3 3 0 XkdW protein Tox-REase-5 PF15648.6 OQR90737.1 - 1.7 9.2 4.9 1.4 9.5 1.2 2.5 2 0 0 2 2 2 0 Restriction endonuclease fold toxin 5 zf-C4H2 PF10146.9 OQR90737.1 - 3.6 7.8 9.3 18 5.6 5.1 2.7 2 0 0 2 2 2 0 Zinc finger-containing protein Ank_2 PF12796.7 OQR90738.1 - 5.8e-92 302.4 37.2 2.1e-19 69.9 1.6 8.4 3 1 4 8 8 8 7 Ankyrin repeats (3 copies) Ank PF00023.30 OQR90738.1 - 5e-90 292.3 46.0 2.5e-09 37.2 0.1 14.9 14 1 1 15 15 15 13 Ankyrin repeat Ank_4 PF13637.6 OQR90738.1 - 7e-69 227.4 14.3 2.4e-11 43.9 0.0 9.9 5 3 5 10 10 10 10 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQR90738.1 - 1.3e-67 215.7 21.6 1.9e-05 24.7 0.0 14.8 14 1 1 15 15 15 13 Ankyrin repeat Ank_5 PF13857.6 OQR90738.1 - 7e-52 172.8 37.4 4.5e-09 36.4 1.6 13.4 4 4 10 14 14 14 12 Ankyrin repeats (many copies) VWA_3_C PF18571.1 OQR90738.1 - 0.0016 18.3 0.4 11 5.9 0.0 6.1 8 0 0 8 8 8 1 von Willebrand factor type A C-terminal domain RNase_PH_C PF03725.15 OQR90738.1 - 0.0018 18.3 1.6 1.3e+02 2.7 0.0 7.4 6 2 3 9 9 9 0 3' exoribonuclease family, domain 2 YfmQ PF10787.9 OQR90738.1 - 0.0033 17.2 0.0 0.35 10.6 0.0 3.8 4 1 0 4 4 4 1 Uncharacterised protein from bacillus cereus group PTS_IIA PF02255.16 OQR90738.1 - 0.3 11.1 4.1 70 3.6 0.6 4.1 3 1 1 4 4 4 0 PTS system, Lactose/Cellobiose specific IIA subunit DUF2149 PF09919.9 OQR90738.1 - 0.46 10.8 3.0 83 3.5 0.2 4.4 4 2 0 4 4 4 0 Uncharacterized conserved protein (DUF2149) DUF4796 PF16044.5 OQR90738.1 - 1.1 8.8 3.0 21 4.6 0.1 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4796) Ank_2 PF12796.7 OQR90739.1 - 8.5e-31 106.4 13.6 2.5e-07 31.2 0.0 4.9 1 1 5 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQR90739.1 - 2.9e-26 91.5 8.1 4.7e-05 23.9 0.1 6.7 4 2 4 8 8 8 6 Ankyrin repeats (many copies) Ank_5 PF13857.6 OQR90739.1 - 2.9e-22 78.4 7.4 0.00026 21.2 0.1 9.8 4 3 5 10 10 10 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQR90739.1 - 1.9e-15 55.4 6.6 1.1 10.0 0.0 10.6 11 1 0 11 11 11 3 Ankyrin repeat DUF3447 PF11929.8 OQR90739.1 - 8e-06 25.7 0.4 1.7 8.7 0.0 4.8 2 1 2 5 5 5 2 Domain of unknown function (DUF3447) Ank PF00023.30 OQR90739.1 - 0.00013 22.2 0.1 40 4.9 0.0 6.1 4 2 0 4 4 4 0 Ankyrin repeat DUF5049 PF16468.5 OQR90739.1 - 0.0072 16.2 0.0 35 4.4 0.0 4.9 5 1 1 6 6 6 0 Domain of unknown function (DUF5049) Pox_A12 PF04651.13 OQR90740.1 - 0.011 15.8 1.4 5.1 7.1 0.0 2.7 1 1 1 2 2 2 0 Poxvirus A12 protein Pullulanase_N2 PF17967.1 OQR90740.1 - 0.022 15.6 1.8 0.022 15.6 1.8 2.3 2 0 0 2 2 2 0 Pullulanase N2 domain SCAB-Ig PF16709.5 OQR90740.1 - 0.074 13.1 0.0 0.19 11.8 0.0 1.8 1 0 0 1 1 1 0 Ig domain of plant-specific actin-binding protein zf-RING_9 PF13901.6 OQR90740.1 - 0.36 10.8 3.5 0.7 9.8 3.5 1.5 1 0 0 1 1 1 0 Putative zinc-RING and/or ribbon Seryl_tRNA_N PF02403.22 OQR90740.1 - 2.1 8.6 19.0 0.32 11.3 8.4 3.1 1 1 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Mito_carr PF00153.27 OQR90741.1 - 5.1e-28 96.8 1.5 1.1e-10 41.3 0.0 3.7 3 1 0 3 3 3 3 Mitochondrial carrier protein HA2 PF04408.23 OQR90741.1 - 4.3e-23 81.7 0.2 4.3e-23 81.7 0.2 2.9 4 0 0 4 4 4 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 OQR90741.1 - 1e-15 57.8 0.0 5e-15 55.6 0.0 2.3 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 OQR90741.1 - 1.4e-10 41.4 0.0 1.1e-09 38.6 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 OQR90741.1 - 2e-07 30.9 0.1 1e-06 28.6 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.6 OQR90741.1 - 0.00038 20.8 1.0 0.0015 18.8 0.0 2.6 3 0 0 3 3 3 1 AAA domain ATPase PF06745.13 OQR90741.1 - 0.058 12.7 0.0 0.17 11.2 0.0 1.7 1 0 0 1 1 1 0 KaiC Glyco_tran_28_C PF04101.16 OQR90742.1 - 5.3e-25 88.3 0.0 6e-25 88.2 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Gal_Lectin PF02140.18 OQR90780.1 - 9.9e-219 708.5 78.8 2.5e-16 59.9 1.3 16.1 15 1 1 16 16 16 16 Galactose binding lectin domain DUF3395 PF11875.8 OQR90780.1 - 0.041 13.8 0.1 1.9e+02 1.8 0.0 5.5 6 0 0 6 6 6 0 Domain of unknown function (DUF3395) PKD_channel PF08016.12 OQR90781.1 - 9.3e-24 83.9 28.2 1.3e-21 76.8 24.0 2.1 2 0 0 2 2 2 2 Polycystin cation channel Ion_trans PF00520.31 OQR90781.1 - 7.3e-07 28.7 27.2 7.3e-07 28.7 27.2 1.6 2 0 0 2 2 2 1 Ion transport protein DUF1521 PF07481.11 OQR90781.1 - 0.035 14.1 0.1 0.062 13.3 0.1 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1521) DUF3810 PF12725.7 OQR90781.1 - 3.6 6.8 17.2 0.017 14.5 6.1 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF3810) PgaD PF13994.6 OQR90781.1 - 3.7 7.6 12.5 0.74 9.9 7.5 2.4 1 1 0 2 2 2 0 PgaD-like protein Lipase_3 PF01764.25 OQR90782.1 - 3e-30 104.9 0.1 6.1e-30 103.9 0.1 1.5 1 0 0 1 1 1 1 Lipase (class 3) DUF4083 PF13314.6 OQR90782.1 - 0.00089 19.2 0.0 0.0037 17.2 0.0 2.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4083) Abhydrolase_3 PF07859.13 OQR90782.1 - 0.025 14.4 0.1 0.072 12.9 0.0 1.7 2 0 0 2 2 2 0 alpha/beta hydrolase fold DUF2974 PF11187.8 OQR90782.1 - 0.027 14.0 0.0 0.079 12.5 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2974) Abhydrolase_6 PF12697.7 OQR90782.1 - 0.079 13.6 0.5 0.44 11.1 0.0 2.2 1 1 0 2 2 2 0 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 OQR90782.1 - 0.11 11.8 0.0 0.2 10.9 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 OQR90782.1 - 0.13 11.8 0.1 0.28 10.8 0.1 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold Peptidase_C13 PF01650.18 OQR90784.1 - 1.9e-101 338.9 0.2 2.7e-101 338.4 0.2 1.1 1 0 0 1 1 1 1 Peptidase C13 family RelB PF04221.12 OQR90784.1 - 0.0081 16.1 0.0 0.017 15.1 0.0 1.5 1 0 0 1 1 1 1 RelB antitoxin NPL PF17800.1 OQR90785.1 - 4.8e-15 56.0 5.6 8.8e-15 55.2 0.0 2.3 2 1 0 2 2 2 1 Nucleoplasmin-like domain Nucleoplasmin PF03066.15 OQR90785.1 - 0.11 13.1 0.0 0.31 11.5 0.0 1.8 1 1 1 2 2 2 0 Nucleoplasmin/nucleophosmin domain GlcNAc PF11397.8 OQR90805.1 - 8.2e-50 170.2 0.6 9.3e-42 143.7 0.2 2.4 1 1 1 2 2 2 2 Glycosyltransferase (GlcNAc) DUF3135 PF11333.8 OQR90807.1 - 0.0037 17.5 1.6 0.0083 16.4 1.6 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3135) Pkinase_Tyr PF07714.17 OQR90808.1 - 2.6e-26 92.5 0.0 7.7e-26 90.9 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OQR90808.1 - 2.1e-21 76.5 0.0 3.6e-21 75.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain LRR_8 PF13855.6 OQR90808.1 - 2e-05 24.2 0.3 0.00021 21.0 0.5 2.5 2 0 0 2 2 2 1 Leucine rich repeat LRR_4 PF12799.7 OQR90808.1 - 0.0017 18.7 1.1 0.012 16.0 0.6 2.6 2 0 0 2 2 2 1 Leucine Rich repeats (2 copies) FNIP PF05725.12 OQR90808.1 - 0.023 14.8 1.9 0.058 13.6 1.9 1.7 1 0 0 1 1 1 0 FNIP Repeat LRR_6 PF13516.6 OQR90808.1 - 0.024 14.7 0.5 15 6.0 0.0 3.3 2 0 0 2 2 2 0 Leucine Rich repeat Asp PF00026.23 OQR90809.1 - 2.8e-36 125.5 4.0 3.6e-36 125.2 4.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 OQR90809.1 - 8.2e-08 32.7 1.9 4.6e-07 30.2 1.9 2.2 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 OQR90809.1 - 0.00046 20.8 0.1 0.038 14.6 0.0 2.5 2 0 0 2 2 2 1 Aspartyl protease TAXi_C PF14541.6 OQR90809.1 - 0.0064 16.3 0.0 0.014 15.2 0.0 1.6 1 0 0 1 1 1 1 Xylanase inhibitor C-terminal CxC3 PF18804.1 OQR90809.1 - 0.12 12.2 5.7 0.78 9.6 1.0 2.5 2 0 0 2 2 2 0 CxC3 like cysteine cluster associated with KDZ transposases Plasmod_dom_1 PF09715.10 OQR90809.1 - 2.2 8.4 4.5 8.7 6.5 1.4 2.8 2 0 0 2 2 2 0 Plasmodium protein of unknown function (Plasmod_dom_1) LapA_dom PF06305.11 OQR90809.1 - 3.2 7.6 4.9 3.7 7.4 0.6 2.3 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain EF-hand_6 PF13405.6 OQR90810.1 - 0.064 13.2 0.1 0.26 11.3 0.1 2.1 1 0 0 1 1 1 0 EF-hand domain Arm-DNA-bind_3 PF13356.6 OQR90810.1 - 0.082 13.3 0.0 0.3 11.5 0.0 1.9 2 0 0 2 2 2 0 Arm DNA-binding domain EF-hand_1 PF00036.32 OQR90810.1 - 0.4 10.3 1.4 0.66 9.7 0.2 2.0 2 0 0 2 2 2 0 EF hand Ank_5 PF13857.6 OQR90813.1 - 4e-23 81.2 12.9 1.9e-05 24.9 0.1 8.7 3 2 6 9 9 9 7 Ankyrin repeats (many copies) Ank_2 PF12796.7 OQR90813.1 - 8.7e-23 80.7 15.4 1.4e-08 35.2 0.4 4.3 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQR90813.1 - 5.3e-21 74.7 17.9 2.3e-05 24.8 0.1 6.4 3 1 4 7 7 7 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQR90813.1 - 1.7e-17 61.7 9.8 0.045 14.3 0.0 9.1 8 1 1 9 9 9 5 Ankyrin repeat DUF5049 PF16468.5 OQR90813.1 - 4.8e-08 32.8 8.9 4.7 7.2 0.0 7.3 2 1 6 8 8 8 4 Domain of unknown function (DUF5049) Ank PF00023.30 OQR90813.1 - 0.054 14.0 8.8 11 6.6 0.0 6.2 5 2 0 5 5 5 0 Ankyrin repeat 2_5_RNA_ligase2 PF13563.6 OQR90823.1 - 1.8e-05 24.7 1.4 3.7e-05 23.7 1.4 1.5 1 0 0 1 1 1 1 2'-5' RNA ligase superfamily DIOX_N PF14226.6 OQR90823.1 - 0.16 12.7 0.0 0.34 11.7 0.0 1.6 1 0 0 1 1 1 0 non-haem dioxygenase in morphine synthesis N-terminal p450 PF00067.22 OQR90826.1 - 0.44 9.2 1.4 8.2 5.0 0.5 2.3 1 1 1 2 2 2 0 Cytochrome P450 MMR_HSR1 PF01926.23 OQR90828.1 - 4.5e-18 65.4 0.1 1.4e-17 63.8 0.0 1.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase NOG1 PF06858.14 OQR90828.1 - 4.9e-16 58.3 0.0 1.2e-15 57.0 0.0 1.7 1 0 0 1 1 1 1 Nucleolar GTP-binding protein 1 (NOG1) NOG1_N PF17835.1 OQR90828.1 - 1.4e-14 54.4 0.7 2.2e-14 53.7 0.7 1.3 1 0 0 1 1 1 1 NOG1 N-terminal helical domain FeoB_N PF02421.18 OQR90828.1 - 5.1e-12 45.6 0.0 8.4e-12 44.9 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 OQR90828.1 - 0.00021 21.3 0.2 0.0023 17.8 0.1 2.5 2 1 0 2 2 2 1 RsgA GTPase AAA_15 PF13175.6 OQR90828.1 - 0.011 15.5 0.0 0.019 14.7 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_23 PF13476.6 OQR90828.1 - 0.015 15.8 0.3 0.057 13.9 0.0 1.9 2 1 0 2 2 2 0 AAA domain DUF815 PF05673.13 OQR90828.1 - 0.054 12.6 0.1 0.42 9.7 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) T3SchapCesA PF11439.8 OQR90828.1 - 0.1 12.8 0.2 0.43 10.8 0.1 2.0 2 0 0 2 2 2 0 Type III secretion system filament chaperone CesA Dynamin_N PF00350.23 OQR90828.1 - 0.11 12.5 1.3 2.2 8.3 0.2 2.6 2 2 0 3 3 3 0 Dynamin family ABC_tran PF00005.27 OQR90828.1 - 0.14 12.7 0.2 0.58 10.7 0.1 2.1 1 1 1 2 2 2 0 ABC transporter Roc PF08477.13 OQR90828.1 - 0.14 12.3 0.0 0.37 11.0 0.0 1.7 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase FYVE PF01363.21 OQR90840.1 - 3e-14 52.9 16.5 7.5e-14 51.6 16.5 1.7 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.16 OQR90840.1 - 0.0013 18.9 10.7 0.003 17.8 10.7 1.5 1 0 0 1 1 1 1 FYVE-type zinc finger DUF2387 PF09526.10 OQR90840.1 - 0.039 14.1 1.7 0.15 12.2 1.7 2.0 1 0 0 1 1 1 0 Probable metal-binding protein (DUF2387) DUF5445 PF17520.2 OQR90840.1 - 0.13 12.2 0.3 0.34 10.8 0.3 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5445) Complex1_LYR PF05347.15 OQR90841.1 - 3.9e-07 30.0 0.0 7.1e-07 29.2 0.0 1.5 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Formin_GBD_N PF18382.1 OQR90841.1 - 0.086 13.3 0.3 0.16 12.4 0.2 1.5 1 1 1 2 2 2 0 Formin N-terminal GTPase-binding domain EST1_DNA_bind PF10373.9 OQR90842.1 - 3.4e-36 125.2 3.3 3.4e-36 125.2 3.3 2.8 3 0 0 3 3 3 1 Est1 DNA/RNA binding domain RNase_Zc3h12a PF11977.8 OQR90842.1 - 3.5e-25 88.6 0.0 9.7e-25 87.2 0.0 1.7 1 1 0 1 1 1 1 Zc3h12a-like Ribonuclease NYN domain Acetyltransf_1 PF00583.25 OQR90842.1 - 1.1e-08 35.3 0.0 2.3e-08 34.3 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 OQR90842.1 - 2.5e-07 30.7 0.0 1.2e-06 28.4 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain EST1 PF10374.9 OQR90842.1 - 2.7e-06 28.1 0.8 0.0006 20.5 0.8 2.9 1 1 0 1 1 1 1 Telomerase activating protein Est1 Acetyltransf_7 PF13508.7 OQR90842.1 - 7.1e-06 26.4 0.0 1.6e-05 25.2 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 OQR90842.1 - 0.022 14.9 1.1 0.03 14.5 0.0 1.7 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain FR47 PF08445.10 OQR90842.1 - 0.051 13.6 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 FR47-like protein GNAT_acetyltran PF12746.7 OQR90842.1 - 0.053 13.1 1.2 0.059 12.9 0.0 1.6 2 0 0 2 2 2 0 GNAT acetyltransferase YL1 PF05764.13 OQR90842.1 - 3.2 7.8 10.0 5.2 7.1 10.0 1.2 1 0 0 1 1 1 0 YL1 nuclear protein Aminotran_1_2 PF00155.21 OQR90843.1 - 2e-68 231.2 0.0 2.3e-68 231.0 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 OQR90843.1 - 0.00018 20.6 0.0 0.00088 18.3 0.0 1.8 2 0 0 2 2 2 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 OQR90843.1 - 0.0002 20.8 0.4 0.00031 20.1 0.4 1.4 1 0 0 1 1 1 1 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.20 OQR90843.1 - 0.0079 14.8 0.0 0.011 14.2 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 OQR90843.1 - 0.015 14.6 0.2 0.073 12.4 0.2 1.9 1 1 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Flg_hook PF02120.16 OQR90843.1 - 0.025 14.5 0.0 0.25 11.3 0.0 2.6 4 0 0 4 4 4 0 Flagellar hook-length control protein FliK HATPase_c_5 PF14501.6 OQR90843.1 - 0.047 13.6 0.0 0.09 12.7 0.0 1.4 1 0 0 1 1 1 0 GHKL domain Hydrolase_4 PF12146.8 OQR90844.1 - 1.9e-21 76.5 0.1 8.2e-12 44.9 0.0 2.4 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 OQR90844.1 - 5.6e-09 35.8 0.0 1.1e-08 34.8 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 OQR90844.1 - 6.5e-09 35.8 0.0 0.002 17.8 0.0 2.4 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 OQR90844.1 - 1.7e-06 28.8 0.0 0.00028 21.5 0.0 2.3 1 1 1 2 2 2 1 Alpha/beta hydrolase family PhoPQ_related PF10142.9 OQR90844.1 - 0.00048 18.9 0.0 0.00085 18.1 0.0 1.3 1 0 0 1 1 1 1 PhoPQ-activated pathogenicity-related protein FSH1 PF03959.13 OQR90844.1 - 0.0013 18.4 0.0 0.0024 17.6 0.0 1.4 1 0 0 1 1 1 1 Serine hydrolase (FSH1) DLH PF01738.18 OQR90844.1 - 0.0046 16.5 0.0 0.014 15.0 0.0 1.8 1 1 0 1 1 1 1 Dienelactone hydrolase family TPR_17 PF13431.6 OQR90844.1 - 0.014 15.7 0.8 0.069 13.6 0.8 2.3 1 0 0 1 1 1 0 Tetratricopeptide repeat LIP PF03583.14 OQR90844.1 - 0.046 13.0 0.1 0.29 10.4 0.0 2.0 2 0 0 2 2 2 0 Secretory lipase LRR_6 PF13516.6 OQR90844.1 - 0.047 13.8 19.1 0.38 10.9 0.2 5.2 5 0 0 5 5 5 0 Leucine Rich repeat Esterase PF00756.20 OQR90844.1 - 0.049 13.3 0.0 0.084 12.5 0.0 1.3 1 0 0 1 1 1 0 Putative esterase GAS PF13851.6 OQR90844.1 - 0.1 11.9 6.4 0.22 10.9 6.4 1.5 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Herpes_DNAp_acc PF04929.12 OQR90844.1 - 7.1 5.5 10.8 0.23 10.4 2.6 1.9 1 1 1 2 2 2 0 Herpes DNA replication accessory factor SMC_N PF02463.19 OQR90845.1 - 7.8e-65 218.4 0.0 2.3e-64 216.9 0.0 1.8 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 OQR90845.1 - 1.9e-24 86.2 0.0 7.4e-24 84.3 0.0 2.1 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_23 PF13476.6 OQR90845.1 - 2.2e-14 54.4 16.0 2.2e-14 54.4 16.0 6.7 2 2 2 4 4 4 1 AAA domain AAA_21 PF13304.6 OQR90845.1 - 1.3e-12 48.2 2.0 3.2e-06 27.2 0.0 3.3 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 OQR90845.1 - 3e-08 33.8 7.0 3e-08 33.8 7.0 4.1 2 2 1 3 3 3 2 AAA ATPase domain AAA_29 PF13555.6 OQR90845.1 - 0.00098 18.8 0.0 0.0022 17.7 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain Pkinase_Tyr PF07714.17 OQR90847.1 - 5.4e-114 379.8 0.0 7.7e-56 189.2 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 OQR90847.1 - 6.4e-101 337.2 0.0 2.7e-51 174.5 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain MafB19-deam PF14437.6 OQR90847.1 - 4.7e-10 39.4 0.2 8.6e-10 38.5 0.2 1.4 1 0 0 1 1 1 1 MafB19-like deaminase dCMP_cyt_deam_1 PF00383.23 OQR90847.1 - 5.6e-08 32.6 1.5 1.2e-07 31.5 1.5 1.5 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region APH PF01636.23 OQR90847.1 - 3.3e-06 27.2 0.6 0.057 13.3 0.1 2.3 2 0 0 2 2 2 2 Phosphotransferase enzyme family Haspin_kinase PF12330.8 OQR90847.1 - 5.3e-06 25.6 0.0 0.47 9.3 0.1 4.2 4 0 0 4 4 4 2 Haspin like kinase domain Pkinase_fungal PF17667.1 OQR90847.1 - 0.0043 15.9 0.0 0.28 9.9 0.0 2.1 2 0 0 2 2 2 1 Fungal protein kinase Bd3614-deam PF14439.6 OQR90847.1 - 0.095 12.8 0.1 0.21 11.7 0.1 1.6 1 0 0 1 1 1 0 Bd3614-like deaminase Allantoicase PF03561.15 OQR90848.1 - 4e-99 328.4 0.0 1.9e-50 170.6 0.0 2.0 2 0 0 2 2 2 2 Allantoicase repeat Ank_2 PF12796.7 OQR90849.1 - 3.3e-69 229.5 12.6 4.9e-16 59.1 1.9 6.7 1 1 6 7 7 7 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQR90849.1 - 2.8e-65 215.9 2.3 9.1e-09 35.7 0.0 9.1 3 3 5 9 9 9 9 Ankyrin repeats (many copies) Ank_5 PF13857.6 OQR90849.1 - 8.4e-53 175.8 16.2 4.7e-12 45.9 0.5 9.2 4 2 5 9 9 9 9 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQR90849.1 - 2.8e-50 162.4 14.5 6.2e-06 26.2 0.3 12.4 13 0 0 13 13 13 9 Ankyrin repeat Ank PF00023.30 OQR90849.1 - 3.3e-47 156.9 24.9 2.1e-06 27.9 0.4 12.1 13 0 0 13 13 13 8 Ankyrin repeat DUF5049 PF16468.5 OQR90849.1 - 0.12 12.2 0.3 26 4.8 0.0 4.3 5 1 0 5 5 5 0 Domain of unknown function (DUF5049) Peptidase_M48 PF01435.18 OQR90850.1 - 1.7e-36 125.8 0.0 4.9e-36 124.4 0.0 1.7 1 1 0 1 1 1 1 Peptidase family M48 DDE_Tnp_4 PF13359.6 OQR90852.1 - 4.3e-08 33.0 0.0 1.6e-07 31.2 0.0 1.7 1 1 0 1 1 1 1 DDE superfamily endonuclease AAA PF00004.29 OQR90853.1 - 1.4e-43 148.5 0.0 3.4e-43 147.2 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) bZIP_1 PF00170.21 OQR90853.1 - 1.5e-11 44.2 14.7 1.5e-11 44.2 14.7 3.3 3 0 0 3 3 3 1 bZIP transcription factor Prot_ATP_ID_OB PF16450.5 OQR90853.1 - 2.1e-09 37.2 0.1 9.7e-09 35.1 0.0 2.2 2 0 0 2 2 2 1 Proteasomal ATPase OB C-terminal domain AAA_5 PF07728.14 OQR90853.1 - 8.2e-09 35.6 0.7 3.4e-07 30.4 0.1 2.8 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) bZIP_2 PF07716.15 OQR90853.1 - 3.6e-08 33.4 11.3 3.6e-08 33.4 11.3 3.5 3 0 0 3 3 3 1 Basic region leucine zipper AAA_2 PF07724.14 OQR90853.1 - 5.9e-08 33.0 0.0 1.6e-07 31.6 0.0 1.8 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_lid_3 PF17862.1 OQR90853.1 - 2.3e-06 27.3 0.1 1.9e-05 24.3 0.0 2.5 2 0 0 2 2 2 1 AAA+ lid domain DUF815 PF05673.13 OQR90853.1 - 0.00012 21.3 0.0 0.0003 20.1 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF815) RuvB_N PF05496.12 OQR90853.1 - 0.00051 19.8 0.0 0.0013 18.5 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 OQR90853.1 - 0.00055 20.3 4.0 0.0045 17.4 0.0 3.0 2 2 0 3 3 3 1 AAA ATPase domain AAA_22 PF13401.6 OQR90853.1 - 0.00062 20.0 0.5 0.061 13.6 0.1 3.2 1 1 1 2 2 2 1 AAA domain DUF3638 PF12340.8 OQR90853.1 - 0.0011 18.3 0.4 0.003 16.9 0.4 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3638) AAA_33 PF13671.6 OQR90853.1 - 0.0012 19.0 0.0 0.0047 17.1 0.0 2.1 2 0 0 2 2 1 1 AAA domain Mg_chelatase PF01078.21 OQR90853.1 - 0.0014 18.1 1.1 0.0032 16.9 0.1 2.0 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI NTPase_1 PF03266.15 OQR90853.1 - 0.0022 17.9 0.1 0.036 14.0 0.0 2.8 3 0 0 3 3 3 1 NTPase RNA_helicase PF00910.22 OQR90853.1 - 0.0028 18.0 0.0 0.018 15.4 0.0 2.4 2 1 0 2 2 1 1 RNA helicase TIP49 PF06068.13 OQR90853.1 - 0.003 16.8 0.0 0.0081 15.4 0.0 1.7 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_28 PF13521.6 OQR90853.1 - 0.0035 17.6 0.0 0.0095 16.2 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 OQR90853.1 - 0.005 17.4 4.0 0.008 16.7 0.0 3.1 3 1 1 4 4 2 1 AAA domain TsaE PF02367.17 OQR90853.1 - 0.0069 16.4 0.0 0.053 13.5 0.0 2.3 1 1 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE IstB_IS21 PF01695.17 OQR90853.1 - 0.0099 15.6 0.0 0.023 14.4 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_30 PF13604.6 OQR90853.1 - 0.013 15.2 0.0 0.03 14.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_3 PF07726.11 OQR90853.1 - 0.018 14.9 0.1 0.1 12.4 0.0 2.3 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Parvo_NS1 PF01057.17 OQR90853.1 - 0.021 13.9 0.0 0.055 12.5 0.0 1.6 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_7 PF12775.7 OQR90853.1 - 0.023 14.2 0.1 0.13 11.7 0.1 2.2 1 1 0 1 1 1 0 P-loop containing dynein motor region AAA_24 PF13479.6 OQR90853.1 - 0.042 13.6 0.0 0.11 12.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 OQR90853.1 - 0.051 13.5 0.1 0.29 11.0 0.0 2.3 3 0 0 3 3 2 0 NACHT domain Sigma54_activat PF00158.26 OQR90853.1 - 0.081 12.6 0.1 0.44 10.2 0.0 2.1 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_14 PF13173.6 OQR90853.1 - 0.094 12.7 0.0 0.3 11.1 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 OQR90853.1 - 0.28 10.8 1.9 1.6 8.3 1.3 2.4 1 1 0 1 1 1 0 AAA domain DUF3175 PF11373.8 OQR90853.1 - 0.3 11.3 1.8 0.66 10.2 0.4 2.4 2 0 0 2 2 1 0 Protein of unknown function (DUF3175) AAA_11 PF13086.6 OQR90853.1 - 0.82 9.4 10.2 1 9.1 0.0 2.8 3 0 0 3 3 3 0 AAA domain YabA PF06156.13 OQR90853.1 - 2.3 8.9 15.0 11 6.8 3.8 3.6 3 0 0 3 3 3 0 Initiation control protein YabA AAA_23 PF13476.6 OQR90853.1 - 5.6 7.4 0.0 5.6 7.4 0.0 3.5 2 1 0 2 2 1 0 AAA domain zf-AN1 PF01428.16 OQR90874.1 - 5.9e-20 71.1 40.5 9e-13 48.2 11.6 4.8 4 1 1 5 5 5 2 AN1-like Zinc finger zf-Di19 PF05605.12 OQR90874.1 - 6.4e-08 32.8 24.1 0.00014 22.1 0.6 4.5 4 0 0 4 4 4 2 Drought induced 19 protein (Di19), zinc-binding Rad50_zn_hook PF04423.14 OQR90874.1 - 7.3e-05 22.5 2.7 0.32 10.9 0.1 3.6 3 0 0 3 3 3 2 Rad50 zinc hook motif zf-C2H2_9 PF16293.5 OQR90874.1 - 7.6e-05 22.5 2.8 0.28 11.1 0.0 3.1 3 0 0 3 3 3 2 C2H2 type zinc-finger (1 copy) zf-C2H2 PF00096.26 OQR90874.1 - 0.00019 21.7 0.6 0.012 16.0 0.2 5.3 7 0 0 7 7 6 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 OQR90874.1 - 0.00047 20.8 1.3 0.067 14.1 0.0 5.8 5 1 1 6 6 5 2 C2H2-type zinc finger FOXP-CC PF16159.5 OQR90874.1 - 0.0023 18.5 10.3 0.39 11.4 0.3 3.8 4 0 0 4 4 4 2 FOXP coiled-coil domain GAGA PF09237.11 OQR90874.1 - 0.0095 15.7 3.6 1 9.2 0.2 3.8 3 0 0 3 3 3 1 GAGA factor zf-met PF12874.7 OQR90874.1 - 0.048 14.1 0.0 0.048 14.1 0.0 4.9 5 0 0 5 5 5 0 Zinc-finger of C2H2 type UBZ_FAAP20 PF15750.5 OQR90874.1 - 0.051 13.5 3.5 14 5.7 0.4 3.6 3 0 0 3 3 3 0 Ubiquitin-binding zinc-finger zf-FPG_IleRS PF06827.14 OQR90874.1 - 0.052 13.4 9.7 0.77 9.7 0.0 4.3 4 0 0 4 4 4 0 Zinc finger found in FPG and IleRS zinc_ribbon_9 PF14369.6 OQR90874.1 - 0.1 12.9 17.4 1.3 9.3 0.4 5.1 5 0 0 5 5 5 0 zinc-ribbon Prok-RING_4 PF14447.6 OQR90874.1 - 2.3 8.2 25.4 4.8 7.1 0.0 4.7 4 1 0 4 4 4 0 Prokaryotic RING finger family 4 zinc_ribbon_5 PF13719.6 OQR90874.1 - 5.6 6.8 20.5 2.8 7.8 0.1 5.0 5 0 0 5 5 4 0 zinc-ribbon domain Dynein_light PF01221.18 OQR90875.1 - 2.1e-43 146.6 1.8 2.3e-43 146.4 1.8 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 Sushi PF00084.20 OQR90876.1 - 2.8e-11 43.8 1.8 4.9e-11 43.1 1.8 1.3 1 0 0 1 1 1 1 Sushi repeat (SCR repeat) DUF547 PF04784.14 OQR90877.1 - 4.7e-18 65.4 0.0 1e-17 64.3 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function, DUF547 ETC_C1_NDUFA4 PF04800.12 OQR90878.1 - 8.6e-29 99.7 0.1 1.7e-28 98.7 0.1 1.5 1 0 0 1 1 1 1 ETC complex I subunit conserved region DUF2188 PF09954.9 OQR90878.1 - 0.082 13.1 0.6 0.28 11.4 0.1 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2188) Pkinase PF00069.25 OQR90880.1 - 0.057 12.8 0.0 0.065 12.6 0.0 1.0 1 0 0 1 1 1 0 Protein kinase domain Phe_tRNA-synt_N PF02912.18 OQR90880.1 - 0.12 12.3 0.1 0.18 11.8 0.1 1.2 1 0 0 1 1 1 0 Aminoacyl tRNA synthetase class II, N-terminal domain Aldedh PF00171.22 OQR90881.1 - 4.5e-75 252.9 0.0 6.6e-75 252.4 0.0 1.1 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 OQR90881.1 - 0.0012 18.4 0.0 0.0059 16.1 0.0 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF1487) DUF2790 PF10976.8 OQR90881.1 - 0.12 12.4 0.0 0.24 11.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2790) Pkinase PF00069.25 OQR90882.1 - 5.8e-88 294.7 0.0 5.8e-49 166.8 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OQR90882.1 - 6.8e-84 281.2 0.0 1.8e-48 165.1 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 OQR90882.1 - 7.7e-10 38.1 0.3 0.0009 18.1 0.1 2.2 2 0 0 2 2 2 2 Fungal protein kinase Kdo PF06293.14 OQR90882.1 - 9.1e-05 21.9 0.0 0.32 10.3 0.0 2.5 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 OQR90882.1 - 0.0001 21.7 0.0 0.18 11.1 0.0 2.5 3 0 0 3 3 3 2 Kinase-like Haspin_kinase PF12330.8 OQR90882.1 - 0.00014 20.9 0.2 0.79 8.6 0.1 3.0 2 1 0 2 2 2 2 Haspin like kinase domain APH PF01636.23 OQR90882.1 - 0.00028 20.9 0.1 0.63 9.9 0.0 2.2 2 0 0 2 2 2 2 Phosphotransferase enzyme family Adeno_E3_CR2 PF02439.15 OQR90882.1 - 0.0017 18.1 1.2 0.0037 17.0 1.2 1.5 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 Vps4_C PF09336.10 OQR90882.1 - 0.015 15.3 0.0 5.3 7.1 0.0 2.6 2 0 0 2 2 2 0 Vps4 C terminal oligomerisation domain PRIMA1 PF16101.5 OQR90882.1 - 0.027 14.5 0.0 2.6 8.1 0.1 3.0 3 0 0 3 3 3 0 Proline-rich membrane anchor 1 CNH PF00780.22 OQR90882.1 - 0.043 13.4 0.1 7.1 6.1 0.0 2.3 2 0 0 2 2 2 0 CNH domain Orf78 PF06024.12 OQR90882.1 - 0.072 13.4 0.0 0.17 12.2 0.0 1.6 1 0 0 1 1 1 0 Orf78 (ac78) HHH_4 PF14490.6 OQR90882.1 - 0.074 13.0 0.0 35 4.5 0.0 3.2 3 0 0 3 3 3 0 Helix-hairpin-helix containing domain SKG6 PF08693.10 OQR90882.1 - 0.35 10.3 7.3 0.077 12.4 3.3 2.1 3 0 0 3 3 3 0 Transmembrane alpha-helix domain TcpE PF12648.7 OQR90882.1 - 0.51 10.9 0.0 0.51 10.9 0.0 2.3 3 0 0 3 3 2 0 TcpE family DnaJ PF00226.31 OQR90884.1 - 2.6e-21 75.5 1.4 2.6e-21 75.5 1.4 2.2 2 0 0 2 2 2 1 DnaJ domain Pox_A_type_inc PF04508.12 OQR90884.1 - 0.031 14.1 4.0 6.3 6.8 0.1 3.1 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat Sec16 PF12932.7 OQR90884.1 - 0.26 11.9 2.1 27 5.4 2.0 2.8 2 0 0 2 2 2 0 Vesicle coat trafficking protein Sec16 mid-region BAG PF02179.16 OQR90884.1 - 1.6 9.2 6.7 0.41 11.1 0.2 3.3 4 0 0 4 4 4 0 BAG domain EMP24_GP25L PF01105.24 OQR90884.1 - 1.7 8.6 15.5 0.081 12.9 3.4 3.5 3 0 0 3 3 3 0 emp24/gp25L/p24 family/GOLD DUF3450 PF11932.8 OQR90884.1 - 5.9 6.1 27.2 0.1 11.9 6.1 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3450) Phage_GP20 PF06810.11 OQR90884.1 - 7.3 6.4 23.1 0.18 11.6 8.8 3.5 3 1 0 3 3 3 0 Phage minor structural protein GP20 ParE_toxin PF05016.15 OQR90884.1 - 9.1 7.0 9.4 5.9 7.6 0.3 3.5 3 0 0 3 3 3 0 ParE toxin of type II toxin-antitoxin system, parDE RSN1_7TM PF02714.15 OQR90886.1 - 1.2e-102 343.0 47.1 2.7e-52 177.8 18.0 2.6 2 0 0 2 2 2 2 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 OQR90886.1 - 4.3e-66 221.5 10.7 8.2e-37 126.4 1.0 5.2 7 0 0 7 7 7 2 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 OQR90886.1 - 5.8e-47 160.2 10.9 2.4e-24 86.5 0.7 4.1 2 2 0 3 3 3 3 Cytosolic domain of 10TM putative phosphate transporter DUF4202 PF13875.6 OQR90886.1 - 0.068 13.1 0.6 7.8 6.3 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4202) ADIP PF11559.8 OQR90887.1 - 0.0077 16.3 8.5 0.0077 16.3 8.5 2.6 3 0 0 3 3 3 1 Afadin- and alpha -actinin-Binding DUF2524 PF10732.9 OQR90887.1 - 0.021 15.1 4.4 0.021 15.1 4.4 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2524) HTH_5 PF01022.20 OQR90887.1 - 0.045 13.6 0.1 0.15 11.9 0.1 2.0 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family DUF4094 PF13334.6 OQR90887.1 - 0.19 12.2 8.1 1.2 9.6 0.2 3.1 2 1 0 2 2 2 0 Domain of unknown function (DUF4094) Aldo_ket_red PF00248.21 OQR90888.1 - 2.2e-45 155.1 1.5 3.5e-44 151.2 0.1 3.3 3 1 0 3 3 3 1 Aldo/keto reductase family Ank_2 PF12796.7 OQR90889.1 - 2.3e-47 159.5 5.9 3.3e-11 43.6 0.0 5.2 3 1 2 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQR90889.1 - 1.7e-41 140.1 7.8 5.8e-11 42.7 0.2 7.8 2 1 7 9 9 9 8 Ankyrin repeats (many copies) Ank PF00023.30 OQR90889.1 - 2.3e-35 119.5 5.4 0.00011 22.4 0.3 10.3 11 0 0 11 11 11 8 Ankyrin repeat Ank_3 PF13606.6 OQR90889.1 - 9.1e-35 114.8 2.8 0.0006 20.1 0.1 9.1 9 0 0 9 9 9 8 Ankyrin repeat Ank_5 PF13857.6 OQR90889.1 - 1.3e-32 111.4 6.6 1.6e-06 28.3 0.1 7.4 3 2 5 8 8 8 7 Ankyrin repeats (many copies) Imm_superinfect PF14373.6 OQR90889.1 - 0.016 15.1 7.3 11 6.0 0.0 5.5 6 0 0 6 6 6 0 Superinfection immunity protein Shigella_OspC PF06128.11 OQR90889.1 - 0.047 13.4 0.2 0.24 11.1 0.3 2.0 2 0 0 2 2 2 0 Shigella flexneri OspC protein BT1 PF03092.16 OQR90890.1 - 2e-14 52.7 0.4 3e-14 52.2 0.4 1.2 1 0 0 1 1 1 1 BT1 family PUCC PF03209.15 OQR90890.1 - 0.034 13.1 5.4 0.14 11.2 0.5 2.4 2 0 0 2 2 2 0 PUCC protein UPF0242 PF06785.11 OQR90891.1 - 0.043 13.9 14.6 0.92 9.6 13.3 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus DASH_Dad2 PF08654.10 OQR90891.1 - 0.049 14.1 11.0 0.2 12.1 6.2 2.5 2 0 0 2 2 2 0 DASH complex subunit Dad2 Inhibitor_G39P PF11417.8 OQR90891.1 - 0.053 14.1 0.3 19 5.9 0.1 3.0 2 0 0 2 2 2 0 Loader and inhibitor of phage G40P Lipase_2 PF01674.18 OQR90891.1 - 0.065 12.7 0.4 3.6 7.0 0.0 2.3 2 0 0 2 2 2 0 Lipase (class 2) LCD1 PF09798.9 OQR90891.1 - 0.11 11.0 9.1 0.21 10.1 9.1 1.4 1 0 0 1 1 1 0 DNA damage checkpoint protein DUF3573 PF12097.8 OQR90891.1 - 0.17 10.7 4.9 2.7 6.7 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3573) IFP_35_N PF07334.13 OQR90891.1 - 0.37 10.9 4.9 13 5.9 0.1 2.7 2 0 0 2 2 2 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus Surfac_D-trimer PF09006.11 OQR90891.1 - 1.4 8.8 4.5 4.4 7.3 0.5 2.6 2 0 0 2 2 2 0 Lung surfactant protein D coiled-coil trimerisation DUF4407 PF14362.6 OQR90891.1 - 4.1 6.7 11.2 2.5 7.4 8.0 2.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4407) Glu-tRNAGln PF02686.15 OQR90891.1 - 4.2 7.8 5.7 19 5.7 0.6 3.2 2 1 1 3 3 3 0 Glu-tRNAGln amidotransferase C subunit DUF4140 PF13600.6 OQR90891.1 - 8.1 6.9 10.0 9 6.8 2.4 3.2 3 1 0 3 3 3 0 N-terminal domain of unknown function (DUF4140) Csm1_N PF18504.1 OQR90891.1 - 9.1 6.7 15.2 16 5.9 1.1 3.6 3 0 0 3 3 3 0 Csm1 N-terminal domain MRAP PF15183.6 OQR90897.1 - 0.13 12.2 1.5 0.2 11.6 0.8 1.6 2 0 0 2 2 2 0 Melanocortin-2 receptor accessory protein family Phage_holin_3_6 PF07332.11 OQR90897.1 - 0.17 11.9 0.7 0.37 10.8 0.7 1.5 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III Kelch_2 PF07646.15 OQR90898.1 - 1.7 8.7 5.0 11 6.1 0.6 3.8 2 0 0 2 2 2 0 Kelch motif PA28_beta PF02252.18 OQR90899.1 - 1.2e-23 83.4 11.0 1.3e-18 67.1 0.3 4.2 4 0 0 4 4 4 2 Proteasome activator pa28 beta subunit Med26 PF08711.11 OQR90899.1 - 5.9e-09 35.8 0.4 1.7e-08 34.3 0.4 1.9 1 0 0 1 1 1 1 TFIIS helical bundle-like domain Peripla_BP_2 PF01497.18 OQR90899.1 - 1.3e-07 31.5 2.5 3.1e-07 30.2 0.0 2.6 3 0 0 3 3 3 1 Periplasmic binding protein Glycoprot_B_PH2 PF17417.2 OQR90899.1 - 0.00075 19.8 2.3 0.0078 16.5 2.3 2.9 1 0 0 1 1 1 1 Herpesvirus Glycoprotein B PH-like domain DEK_C PF08766.11 OQR90899.1 - 0.0018 18.2 0.5 0.0079 16.1 0.5 2.3 1 0 0 1 1 1 1 DEK C terminal domain 2OG-Fe_Oxy_2 PF10014.9 OQR90899.1 - 0.2 11.4 2.8 0.22 11.3 0.6 2.2 2 0 0 2 2 2 0 2OG-Fe dioxygenase T3SchapCesA PF11439.8 OQR90899.1 - 4.1 7.6 10.2 0.93 9.7 1.6 3.6 3 0 0 3 3 3 0 Type III secretion system filament chaperone CesA RPN6_N PF18055.1 OQR90901.1 - 2.3e-28 98.9 1.9 1.1e-27 96.7 0.0 2.5 2 1 0 2 2 2 1 26S proteasome regulatory subunit RPN6 N-terminal domain PCI PF01399.27 OQR90901.1 - 3.3e-18 66.1 6.5 3.1e-17 63.0 0.6 2.8 2 1 0 2 2 2 1 PCI domain RPN6_C_helix PF18503.1 OQR90901.1 - 5.2e-11 42.1 0.3 2.1e-09 36.9 0.0 2.8 2 0 0 2 2 2 1 26S proteasome subunit RPN6 C-terminal helix domain TPR_MalT PF17874.1 OQR90901.1 - 0.0056 16.1 6.9 0.0078 15.6 5.4 1.9 1 1 1 2 2 2 1 MalT-like TPR region TPR_12 PF13424.6 OQR90901.1 - 0.013 15.8 3.2 0.013 15.8 3.2 3.5 4 1 0 4 4 4 0 Tetratricopeptide repeat ComR_TPR PF18710.1 OQR90901.1 - 0.016 14.7 1.3 0.041 13.4 1.3 1.7 1 0 0 1 1 1 0 ComR tetratricopeptide TPR_7 PF13176.6 OQR90901.1 - 0.027 14.5 9.8 0.48 10.6 0.2 4.6 5 0 0 5 5 5 0 Tetratricopeptide repeat DDRGK PF09756.9 OQR90901.1 - 0.095 12.3 0.0 0.19 11.3 0.0 1.4 1 0 0 1 1 1 0 DDRGK domain DUF410 PF04190.13 OQR90901.1 - 0.14 12.0 3.2 1.2 8.8 0.6 2.3 1 1 0 2 2 2 0 Protein of unknown function (DUF410) TPR_19 PF14559.6 OQR90901.1 - 0.79 10.3 7.1 0.24 11.9 1.5 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.6 OQR90901.1 - 1 10.1 7.7 12 6.7 0.9 3.5 3 2 0 3 3 2 0 Tetratricopeptide repeat TPR_2 PF07719.17 OQR90901.1 - 4.2 7.7 13.5 13 6.2 0.0 5.2 6 1 1 7 7 7 0 Tetratricopeptide repeat TFCD_C PF12612.8 OQR90902.1 - 1.8e-45 155.1 0.6 2e-44 151.7 0.0 2.8 4 0 0 4 4 4 1 Tubulin folding cofactor D C terminal HEAT_2 PF13646.6 OQR90902.1 - 3e-06 27.5 4.0 2.5 8.5 0.0 5.7 6 0 0 6 6 6 3 HEAT repeats HEAT_EZ PF13513.6 OQR90902.1 - 2.2e-05 24.8 11.1 2 9.0 0.0 7.2 7 0 0 7 7 7 2 HEAT-like repeat HEAT PF02985.22 OQR90902.1 - 0.0038 17.4 21.8 0.55 10.6 0.0 8.7 9 0 0 9 9 9 2 HEAT repeat Cnd1 PF12717.7 OQR90902.1 - 0.0054 16.8 0.3 17 5.5 0.0 4.4 4 1 0 4 4 4 2 non-SMC mitotic condensation complex subunit 1 Cnd3 PF12719.7 OQR90902.1 - 0.042 13.0 3.4 2 7.6 0.0 4.0 5 0 0 5 5 5 0 Nuclear condensing complex subunits, C-term domain Nuc_sug_transp PF04142.15 OQR90913.1 - 6.3e-70 235.8 26.2 7.6e-70 235.6 26.2 1.1 1 0 0 1 1 1 1 Nucleotide-sugar transporter UAA PF08449.11 OQR90913.1 - 4.8e-05 22.7 21.3 4.8e-05 22.7 21.3 2.0 1 1 1 2 2 2 1 UAA transporter family PUNUT PF16913.5 OQR90913.1 - 0.00014 21.3 18.2 0.00014 21.3 18.2 1.9 1 1 1 2 2 2 1 Purine nucleobase transmembrane transport EamA PF00892.20 OQR90913.1 - 0.0056 16.9 11.2 0.0056 16.9 11.2 3.4 2 2 0 2 2 2 1 EamA-like transporter family TPT PF03151.16 OQR90913.1 - 0.0067 15.8 19.9 0.19 11.1 19.9 2.7 1 1 0 1 1 1 1 Triose-phosphate Transporter family OB_aCoA_assoc PF01796.17 OQR90913.1 - 0.08 13.0 0.0 0.15 12.1 0.0 1.5 1 0 0 1 1 1 0 DUF35 OB-fold domain, acyl-CoA-associated DUF3188 PF11384.8 OQR90913.1 - 0.088 12.5 0.2 0.088 12.5 0.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3188) Usp PF00582.26 OQR90914.1 - 5.6e-12 46.4 0.0 7.2e-05 23.3 0.0 3.2 2 1 1 3 3 3 3 Universal stress protein family Pkinase PF00069.25 OQR90915.1 - 1.5e-71 240.9 0.0 2.3e-71 240.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQR90915.1 - 1.1e-32 113.4 0.0 1.8e-32 112.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase PX PF00787.24 OQR90915.1 - 2.5e-15 56.4 0.2 6e-15 55.2 0.2 1.6 1 0 0 1 1 1 1 PX domain Kinase-like PF14531.6 OQR90915.1 - 1.3e-07 31.2 0.0 5.3e-07 29.2 0.0 1.8 2 0 0 2 2 2 1 Kinase-like Pkinase_C PF00433.24 OQR90915.1 - 0.00056 20.6 5.1 0.0017 19.1 1.2 3.2 3 0 0 3 3 3 1 Protein kinase C terminal domain APH PF01636.23 OQR90915.1 - 0.017 15.0 0.1 0.09 12.7 0.0 2.2 2 1 0 2 2 2 0 Phosphotransferase enzyme family FTA2 PF13095.6 OQR90915.1 - 0.02 14.5 0.0 4.6 6.8 0.0 2.3 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Pkinase_fungal PF17667.1 OQR90915.1 - 0.092 11.5 0.0 0.18 10.6 0.0 1.4 1 0 0 1 1 1 0 Fungal protein kinase Seadorna_VP7 PF07387.11 OQR90915.1 - 0.11 11.5 0.0 0.21 10.6 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 Itfg2 PF15907.5 OQR90916.1 - 7e-14 51.6 0.8 1.5e-12 47.2 0.1 2.7 2 1 1 4 4 4 1 Integrin-alpha FG-GAP repeat-containing protein 2 BBS2_Mid PF14783.6 OQR90916.1 - 2.7e-06 27.4 0.9 0.27 11.3 0.0 3.5 3 1 1 4 4 4 2 Ciliary BBSome complex subunit 2, middle region BBS1 PF14779.6 OQR90916.1 - 0.00017 21.1 0.5 1.6 8.1 0.1 3.4 2 1 1 4 4 4 3 Ciliary BBSome complex subunit 1 FG-GAP PF01839.23 OQR90916.1 - 0.0083 16.2 0.0 0.018 15.2 0.0 1.5 1 0 0 1 1 1 1 FG-GAP repeat VCBS PF13517.6 OQR90916.1 - 0.14 12.8 0.3 0.7 10.5 0.1 2.3 2 0 0 2 2 2 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella ELMO_CED12 PF04727.13 OQR90917.1 - 1.4e-12 48.1 0.4 3.1e-12 47.0 0.1 1.6 2 0 0 2 2 2 1 ELMO/CED-12 family DIX PF00778.17 OQR90917.1 - 0.0087 15.9 0.0 0.016 15.0 0.0 1.4 1 0 0 1 1 1 1 DIX domain Ank_2 PF12796.7 OQR90935.1 - 2.7e-11 43.9 1.3 0.00027 21.5 0.0 3.9 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQR90935.1 - 8.2e-05 23.1 4.8 0.18 12.5 0.0 5.2 4 2 1 5 5 5 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 OQR90935.1 - 0.00011 22.4 0.4 9.5 6.7 0.0 4.9 4 0 0 4 4 4 2 Ankyrin repeats (many copies) Ank PF00023.30 OQR90935.1 - 0.0032 17.9 8.0 19 5.9 0.2 6.1 6 0 0 6 6 6 1 Ankyrin repeat Ank_3 PF13606.6 OQR90935.1 - 0.028 14.9 7.9 16 6.5 0.2 5.8 7 0 0 7 7 7 0 Ankyrin repeat UPF0020 PF01170.18 OQR90936.1 - 1.1e-08 35.1 0.0 4.8e-06 26.4 0.0 2.3 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 MethyltransfD12 PF02086.15 OQR90936.1 - 0.1 12.3 0.3 0.52 9.9 0.0 2.1 1 1 1 2 2 2 0 D12 class N6 adenine-specific DNA methyltransferase Ank_2 PF12796.7 OQR90937.1 - 0.051 14.2 0.1 0.16 12.6 0.1 1.8 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OQR90937.1 - 0.15 12.4 0.0 0.48 10.8 0.0 1.9 1 0 0 1 1 1 0 Ankyrin repeats (many copies) PHD PF00628.29 OQR90937.1 - 0.33 10.9 8.2 0.85 9.6 8.2 1.7 1 1 0 1 1 1 0 PHD-finger RNA_pol_Rpb4 PF03874.16 OQR90938.1 - 2.6e-17 63.3 1.7 4.8e-17 62.4 1.7 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb4 RNA_pol_Rpb4 PF03874.16 OQR90948.1 - 1.8e-18 67.0 0.3 2.4e-18 66.6 0.3 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb4 Sec15 PF04091.12 OQR90948.1 - 0.0052 16.2 0.0 0.0055 16.1 0.0 1.2 1 0 0 1 1 1 1 Exocyst complex subunit Sec15-like SLATT_6 PF18169.1 OQR90949.1 - 0.053 13.1 0.0 0.1 12.2 0.0 1.4 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain 6 Ank_2 PF12796.7 OQR90950.1 - 3e-139 454.0 34.8 5.5e-16 58.9 0.3 10.4 2 2 12 14 14 14 13 Ankyrin repeats (3 copies) Ank PF00023.30 OQR90950.1 - 1.6e-85 278.1 37.1 7.4e-07 29.3 0.0 16.3 16 0 0 16 16 16 16 Ankyrin repeat Ank_4 PF13637.6 OQR90950.1 - 6.5e-79 259.4 11.8 7e-11 42.4 0.0 13.7 4 2 9 14 14 14 14 Ankyrin repeats (many copies) Ank_5 PF13857.6 OQR90950.1 - 4.7e-72 237.1 15.8 4.6e-09 36.4 0.5 13.2 5 4 9 14 14 14 13 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQR90950.1 - 8.3e-60 191.7 4.1 0.00016 21.8 0.2 16.4 16 0 0 16 16 16 11 Ankyrin repeat Mqo PF06039.15 OQR90950.1 - 6.8e-05 21.6 0.0 0.8 8.2 0.0 4.4 2 1 2 4 4 4 3 Malate:quinone oxidoreductase (Mqo) Imm_superinfect PF14373.6 OQR90950.1 - 0.00043 20.1 6.7 3.9 7.5 0.0 7.3 7 0 0 7 7 7 1 Superinfection immunity protein CM_1 PF07736.11 OQR90950.1 - 0.015 15.7 3.1 45 4.5 0.0 5.0 4 2 1 5 5 5 0 Chorismate mutase type I DUF4541 PF15074.6 OQR90950.1 - 0.045 14.3 0.0 1.4 9.6 0.0 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4541) ATPase PF06745.13 OQR90950.1 - 0.092 12.1 0.0 16 4.8 0.0 3.4 3 0 0 3 3 3 0 KaiC RRM_1 PF00076.22 OQR90951.1 - 1.8e-42 143.0 1.0 1.4e-20 72.9 0.1 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RBM39linker PF15519.6 OQR90951.1 - 6.3e-15 56.0 0.1 2e-14 54.4 0.1 1.9 1 0 0 1 1 1 1 linker between RRM2 and RRM3 domains in RBM39 protein RRM_7 PF16367.5 OQR90951.1 - 0.0014 18.7 0.1 0.81 9.9 0.0 2.9 2 0 0 2 2 2 2 RNA recognition motif RRM_5 PF13893.6 OQR90951.1 - 0.01 15.4 0.0 0.034 13.8 0.0 1.8 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RL PF17797.1 OQR90951.1 - 0.034 14.1 0.1 1.9 8.5 0.0 2.8 3 0 0 3 3 3 0 RL domain RRM_occluded PF16842.5 OQR90951.1 - 0.06 13.2 0.1 3.6 7.5 0.0 2.7 3 0 0 3 3 3 0 Occluded RNA-recognition motif RRM_3 PF08777.11 OQR90951.1 - 0.084 12.9 0.9 0.62 10.1 0.0 2.7 4 0 0 4 4 4 0 RNA binding motif HEPN_RnaseLS PF18869.1 OQR90951.1 - 0.092 12.9 0.0 0.18 11.9 0.0 1.4 1 0 0 1 1 1 0 RnaseLS-like HEPN FAM76 PF16046.5 OQR90951.1 - 1.2 8.4 10.7 2.1 7.7 10.7 1.3 1 0 0 1 1 1 0 FAM76 protein vATP-synt_E PF01991.18 OQR90952.1 - 8.2e-47 159.2 5.7 1e-46 158.9 5.7 1.1 1 0 0 1 1 1 1 ATP synthase (E/31 kDa) subunit SIR2 PF02146.17 OQR90953.1 - 2.5e-47 161.1 0.3 6.3e-47 159.8 0.3 1.6 1 1 0 1 1 1 1 Sir2 family DNA_ligase_ZBD PF03119.16 OQR90953.1 - 0.083 12.9 0.4 8.2 6.5 0.1 2.5 2 0 0 2 2 2 0 NAD-dependent DNA ligase C4 zinc finger domain Proteasome PF00227.26 OQR90954.1 - 1.8e-34 118.9 0.1 2.4e-34 118.5 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit TraI_2_C PF07515.11 OQR90954.1 - 0.056 13.4 0.0 0.12 12.3 0.0 1.6 2 0 0 2 2 2 0 Putative conjugal transfer nickase/helicase TraI C-term DUF4073 PF13285.6 OQR90954.1 - 0.095 12.3 0.0 0.24 11.0 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4073) PFU PF09070.11 OQR90970.1 - 1.7e-11 44.4 2.0 0.0014 18.8 0.0 3.1 2 1 1 3 3 3 3 PFU (PLAA family ubiquitin binding) DUF1327 PF07041.11 OQR90970.1 - 0.064 13.3 0.0 2.6 8.1 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1327) Aldedh PF00171.22 OQR90971.1 - 0.0014 17.3 0.1 0.0017 17.0 0.1 1.1 1 0 0 1 1 1 1 Aldehyde dehydrogenase family cNMP_binding PF00027.29 OQR90977.1 - 1.5e-17 63.4 0.0 2.8e-17 62.6 0.0 1.5 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Ion_trans PF00520.31 OQR90977.1 - 1.8e-13 50.3 16.8 2.7e-13 49.7 16.8 1.2 1 0 0 1 1 1 1 Ion transport protein RNR_Alpha PF17975.1 OQR90977.1 - 0.04 14.4 0.1 10 6.7 0.0 2.5 2 0 0 2 2 2 0 Ribonucleotide reductase alpha domain Pkinase_Tyr PF07714.17 OQR90978.1 - 9.8e-35 120.1 0.0 1.4e-34 119.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OQR90978.1 - 2.6e-29 102.4 0.0 3.8e-29 101.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain C2 PF00168.30 OQR90978.1 - 8.1e-16 58.2 0.0 1.7e-15 57.2 0.0 1.5 1 0 0 1 1 1 1 C2 domain HMG_CoA_synt_C PF08540.10 OQR90979.1 - 5.7e-87 291.9 0.3 9.4e-87 291.2 0.1 1.5 2 0 0 2 2 2 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal HMG_CoA_synt_N PF01154.17 OQR90979.1 - 7.9e-82 273.3 0.1 1.2e-81 272.8 0.1 1.2 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal DUF2614 PF11023.8 OQR90979.1 - 0.13 12.3 0.0 0.4 10.8 0.0 1.8 1 0 0 1 1 1 0 Zinc-ribbon containing domain Ferric_reduct PF01794.19 OQR90986.1 - 8.5e-17 61.4 9.1 8.5e-17 61.4 9.1 2.5 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 OQR90986.1 - 1.1e-09 38.6 0.0 4.9e-07 30.0 0.0 2.7 1 1 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 OQR90986.1 - 6.2e-09 35.9 0.0 1.6e-08 34.6 0.0 1.7 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_1 PF00175.21 OQR90986.1 - 3.1e-06 27.8 0.0 9.2e-06 26.3 0.0 1.9 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain PI3K_C2 PF00792.24 OQR90986.1 - 0.026 14.4 0.2 0.096 12.6 0.0 2.0 2 0 0 2 2 2 0 Phosphoinositide 3-kinase C2 DUF3836 PF12930.7 OQR90986.1 - 0.24 11.1 2.5 5.5 6.8 0.0 3.2 3 0 0 3 3 3 0 Family of unknown function (DUF3836) DUF4405 PF14358.6 OQR90986.1 - 0.31 11.6 17.9 0.081 13.5 5.2 3.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4405) MPM1 PF17234.2 OQR90986.1 - 0.42 10.8 2.8 64 3.8 0.1 3.3 3 0 0 3 3 3 0 Mitochondrial peculiar membrane protein 1 Retrotran_gag_2 PF14223.6 OQR90994.1 - 0.015 14.9 0.0 0.023 14.4 0.0 1.3 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type Pkinase PF00069.25 OQR91004.1 - 3.7e-05 23.2 0.0 0.0011 18.3 0.0 2.2 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQR91004.1 - 0.081 12.2 0.0 0.94 8.7 0.0 2.1 1 1 0 1 1 1 0 Protein tyrosine kinase Mannosyl_trans3 PF11051.8 OQR91005.1 - 2.9e-33 115.4 0.0 3e-31 108.8 0.0 2.1 1 1 0 1 1 1 1 Mannosyltransferase putative Myb_DNA-binding PF00249.31 OQR91007.1 - 4.2e-39 132.5 9.5 9.3e-15 54.6 0.5 4.4 5 0 0 5 5 5 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OQR91007.1 - 3.9e-33 113.5 3.5 3.4e-15 56.0 0.2 3.7 1 1 2 3 3 3 3 Myb-like DNA-binding domain DSPc PF00782.20 OQR91007.1 - 9.9e-28 96.6 0.0 1.7e-27 95.9 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain EGF_2 PF07974.13 OQR91007.1 - 2.2e-08 34.3 89.2 0.00081 19.7 5.9 9.3 8 1 0 8 8 8 6 EGF-like domain MMR_HSR1 PF01926.23 OQR91007.1 - 4.9e-06 26.6 0.0 1e-05 25.6 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase PTPlike_phytase PF14566.6 OQR91007.1 - 5.3e-05 23.4 0.0 9.6e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 Inositol hexakisphosphate ABC_tran PF00005.27 OQR91007.1 - 0.0036 17.8 0.0 0.0074 16.8 0.0 1.4 1 0 0 1 1 1 1 ABC transporter RsgA_GTPase PF03193.16 OQR91007.1 - 0.0049 16.8 0.0 0.012 15.5 0.0 1.6 1 0 0 1 1 1 1 RsgA GTPase AAA_16 PF13191.6 OQR91007.1 - 0.0082 16.5 0.0 0.017 15.5 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain Myb_DNA-bind_4 PF13837.6 OQR91007.1 - 0.01 16.2 2.9 8.2 6.9 0.0 3.4 3 0 0 3 3 3 0 Myb/SANT-like DNA-binding domain Y_phosphatase PF00102.27 OQR91007.1 - 0.026 14.1 0.0 0.056 13.0 0.0 1.5 1 0 0 1 1 1 0 Protein-tyrosine phosphatase IIGP PF05049.13 OQR91007.1 - 0.18 10.8 0.0 0.35 9.9 0.0 1.4 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) IstB_IS21 PF01695.17 OQR91007.1 - 0.23 11.2 0.0 0.42 10.3 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein Pkinase_Tyr PF07714.17 OQR91008.1 - 5.9e-46 156.8 0.0 1.7e-27 96.4 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 OQR91008.1 - 6.8e-39 133.8 0.0 1.9e-37 129.1 0.0 2.6 2 1 0 2 2 2 1 Protein kinase domain DUF979 PF06166.12 OQR91008.1 - 0.013 14.7 0.8 0.05 12.8 0.8 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF979) DUF2106 PF09879.9 OQR91008.1 - 0.1 12.1 1.1 1.1 8.8 0.0 2.8 3 0 0 3 3 3 0 Predicted membrane protein (DUF2106) Clathrin PF00637.20 OQR91009.1 - 0.0089 15.9 0.4 0.045 13.6 0.1 2.1 2 1 0 2 2 2 1 Region in Clathrin and VPS IQ PF00612.27 OQR91010.1 - 5e-14 50.7 8.7 3e-05 23.4 0.2 4.3 4 0 0 4 4 4 3 IQ calmodulin-binding motif Spb1_C PF07780.12 OQR91011.1 - 1.3e-58 198.2 25.7 1.3e-58 198.2 25.7 2.9 2 1 1 3 3 3 1 Spb1 C-terminal domain Ank_2 PF12796.7 OQR91012.1 - 5.7e-29 100.5 8.9 1.8e-11 44.5 0.9 3.2 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) zf-C3HC4_3 PF13920.6 OQR91012.1 - 1.1e-24 86.0 34.2 3.3e-13 49.3 11.9 2.5 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) Ank_5 PF13857.6 OQR91012.1 - 1.2e-24 86.0 2.7 5e-08 33.1 0.0 4.3 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank_4 PF13637.6 OQR91012.1 - 5.3e-23 81.1 4.0 3e-10 40.4 0.1 3.5 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQR91012.1 - 3e-21 73.2 3.8 0.00011 22.3 0.3 6.4 6 0 0 6 6 6 4 Ankyrin repeat Ank PF00023.30 OQR91012.1 - 1.1e-19 70.0 7.1 1.1e-06 28.8 0.7 4.8 4 0 0 4 4 4 4 Ankyrin repeat Prok-RING_4 PF14447.6 OQR91012.1 - 8.8e-08 31.9 35.1 0.00014 21.7 12.8 2.6 2 0 0 2 2 2 2 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 OQR91012.1 - 7.6e-06 26.2 40.8 0.00027 21.2 13.6 2.9 3 0 0 3 3 2 2 Ring finger domain zf-C3HC4_2 PF13923.6 OQR91012.1 - 0.003 17.4 38.8 0.045 13.6 14.2 2.6 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OQR91012.1 - 0.34 10.9 36.2 0.23 11.5 13.2 2.6 2 0 0 2 2 2 0 zinc-RING finger domain DUF393 PF04134.12 OQR91012.1 - 1.2 10.5 3.3 99 4.3 0.0 3.9 4 0 0 4 4 3 0 Protein of unknown function, DUF393 zf-RING_4 PF14570.6 OQR91012.1 - 3.1 7.7 30.2 1.2 8.9 10.2 2.5 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain DUF5318 PF17249.2 OQR91012.1 - 7 6.4 6.1 17 5.2 0.3 2.6 2 0 0 2 2 2 0 Family of unknown function (DUF5318) Rad50_zn_hook PF04423.14 OQR91012.1 - 8 6.4 6.4 31 4.5 1.3 2.5 2 0 0 2 2 2 0 Rad50 zinc hook motif DUF4392 PF14336.6 OQR91013.1 - 5.6e-67 226.3 0.1 8.8e-67 225.6 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4392) C2 PF00168.30 OQR91013.1 - 0.021 15.1 0.0 0.11 12.7 0.0 2.2 1 1 0 1 1 1 0 C2 domain Mga PF05043.13 OQR91013.1 - 0.31 11.7 0.8 1 10.0 0.3 2.1 2 0 0 2 2 2 0 Mga helix-turn-helix domain EamA PF00892.20 OQR91071.1 - 4.6e-06 26.9 7.6 4.6e-06 26.9 7.6 1.5 2 0 0 2 2 2 1 EamA-like transporter family TMEM234 PF10639.9 OQR91071.1 - 0.005 16.9 0.9 0.0059 16.6 0.9 1.2 1 0 0 1 1 1 1 Putative transmembrane family 234 UAA PF08449.11 OQR91071.1 - 0.006 15.8 1.7 0.0069 15.6 1.7 1.1 1 0 0 1 1 1 1 UAA transporter family UPF0060 PF02694.15 OQR91071.1 - 0.039 14.2 1.0 0.058 13.6 1.0 1.4 1 0 0 1 1 1 0 Uncharacterised BCR, YnfA/UPF0060 family DUF3493 PF11998.8 OQR91071.1 - 3.3 8.0 5.5 1.2 9.3 2.1 1.9 2 0 0 2 2 2 0 Low psii accumulation1 / Rep27 EF-hand_6 PF13405.6 OQR91072.1 - 0.0024 17.6 0.0 0.15 12.0 0.0 3.6 4 0 0 4 4 4 1 EF-hand domain EF-hand_2 PF09068.11 OQR91072.1 - 0.0071 16.5 0.0 0.063 13.4 0.0 2.6 2 0 0 2 2 2 1 EF hand EF-hand_1 PF00036.32 OQR91072.1 - 0.019 14.5 0.0 0.38 10.4 0.0 2.9 3 0 0 3 3 3 0 EF hand EF-hand_8 PF13833.6 OQR91072.1 - 0.052 13.4 0.0 0.48 10.3 0.0 2.6 1 1 0 1 1 1 0 EF-hand domain pair PP2C PF00481.21 OQR91073.1 - 1.2e-39 136.6 0.0 3.3e-39 135.1 0.0 1.7 1 1 0 1 1 1 1 Protein phosphatase 2C HpcH_HpaI PF03328.14 OQR91074.1 - 1.3e-97 325.2 0.6 1.2e-47 162.0 0.2 2.5 3 0 0 3 3 3 2 HpcH/HpaI aldolase/citrate lyase family C-C_Bond_Lyase PF15617.6 OQR91074.1 - 9.8e-12 44.7 7.5 4.7e-05 22.7 0.1 4.6 4 2 0 4 4 4 3 C-C_Bond_Lyase of the TIM-Barrel fold PEP-utilizers_C PF02896.18 OQR91074.1 - 1.2e-06 27.9 0.2 0.067 12.3 0.0 3.2 3 0 0 3 3 3 2 PEP-utilising enzyme, TIM barrel domain DUF2280 PF10045.9 OQR91074.1 - 0.0007 19.8 0.0 0.12 12.6 0.0 2.7 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2280) RisS_PPD PF16524.5 OQR91074.1 - 0.055 13.7 0.0 0.96 9.7 0.0 2.6 2 0 0 2 2 2 0 Periplasmic domain of Sensor histidine kinase RisS Ank_2 PF12796.7 OQR91075.1 - 1.4e-17 64.0 4.8 1.1e-10 41.9 0.6 2.5 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQR91075.1 - 1.2e-15 57.6 0.7 4e-10 40.0 0.2 3.0 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 OQR91075.1 - 8.1e-12 45.1 1.4 6.3e-06 26.4 0.1 3.0 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQR91075.1 - 3.7e-11 42.2 1.4 0.009 16.5 0.0 5.6 6 0 0 6 6 6 3 Ankyrin repeat RRM_1 PF00076.22 OQR91075.1 - 2.6e-09 36.8 0.0 2.7e-06 27.1 0.0 2.7 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ank PF00023.30 OQR91075.1 - 0.00012 22.4 4.4 1.3 9.6 0.1 4.1 4 0 0 4 4 4 2 Ankyrin repeat WD40 PF00400.32 OQR91077.1 - 1e-44 149.6 22.4 4.8e-08 33.5 0.3 7.6 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OQR91077.1 - 1.7e-11 44.3 2.2 0.24 11.7 0.0 6.7 2 2 4 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 OQR91077.1 - 2.3e-05 23.9 0.0 0.0002 20.8 0.1 2.3 1 1 1 2 2 2 1 WD40-like domain Nup160 PF11715.8 OQR91077.1 - 0.00024 19.9 2.2 0.49 9.0 0.5 4.1 2 1 1 4 4 4 2 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 OQR91077.1 - 0.015 14.3 0.5 2.4 7.1 0.0 3.6 3 1 1 5 5 5 0 WD40 region of Ge1, enhancer of mRNA-decapping protein LisH PF08513.11 OQR91077.1 - 0.017 15.0 0.9 0.032 14.2 0.0 2.0 2 0 0 2 2 2 0 LisH PQQ PF01011.21 OQR91077.1 - 0.018 15.0 0.2 9.9 6.3 0.1 3.3 3 0 0 3 3 3 0 PQQ enzyme repeat Frtz PF11768.8 OQR91077.1 - 0.021 13.2 0.0 3.1 6.0 0.0 2.5 2 1 0 2 2 2 0 WD repeat-containing and planar cell polarity effector protein Fritz PQQ_3 PF13570.6 OQR91077.1 - 0.52 10.9 2.6 26 5.5 0.1 3.7 4 0 0 4 4 4 0 PQQ-like domain MTP18 PF10558.9 OQR91078.1 - 7.2e-23 81.4 1.3 7.9e-13 48.7 0.2 2.0 1 1 1 2 2 2 2 Mitochondrial 18 KDa protein (MTP18) Peptidase_M24 PF00557.24 OQR91079.1 - 1.6e-60 204.4 0.1 2.2e-60 203.9 0.1 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.16 OQR91079.1 - 5.8e-25 87.4 0.0 2e-24 85.7 0.0 1.9 2 0 0 2 2 2 1 Aminopeptidase P, N-terminal domain CC2-LZ PF16516.5 OQR91079.1 - 0.16 12.3 0.0 0.39 11.1 0.0 1.5 1 0 0 1 1 1 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator Mannosyl_trans3 PF11051.8 OQR91080.1 - 1e-35 123.5 0.0 1.7e-35 122.7 0.0 1.3 1 0 0 1 1 1 1 Mannosyltransferase putative Sulfate_transp PF00916.20 OQR91081.1 - 1.9e-22 79.6 26.0 3.3e-22 78.8 26.0 1.3 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 OQR91081.1 - 0.012 15.2 0.0 0.024 14.3 0.0 1.5 1 0 0 1 1 1 0 STAS domain Ribosomal_S5 PF00333.20 OQR91111.1 - 1.9e-28 98.2 1.5 4.2e-28 97.1 1.5 1.6 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.15 OQR91111.1 - 1.4e-25 88.5 0.0 3.2e-25 87.4 0.0 1.6 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain DUF5320 PF17253.2 OQR91111.1 - 0.18 12.9 7.1 1.6 9.9 3.5 2.7 3 0 0 3 3 3 0 Family of unknown function (DUF5320) FoP_duplication PF13865.6 OQR91111.1 - 4.1 8.0 11.4 7.9 7.1 11.4 1.4 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 Pkinase PF00069.25 OQR91113.1 - 7.7e-11 41.9 0.0 1e-10 41.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQR91113.1 - 5.9e-07 29.0 0.0 7.8e-07 28.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Chitin_synth_1 PF01644.17 OQR91117.1 - 5.3e-50 169.6 0.0 8.8e-50 168.9 0.0 1.4 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_2 PF03142.15 OQR91117.1 - 3.2e-27 95.3 4.1 1.1e-20 73.8 0.0 3.5 3 1 0 4 4 4 2 Chitin synthase Glyco_trans_2_3 PF13632.6 OQR91117.1 - 1.5e-08 34.8 11.3 1.5e-08 34.8 11.3 2.9 2 1 0 2 2 2 1 Glycosyl transferase family group 2 MIT PF04212.18 OQR91117.1 - 0.00052 20.0 0.2 0.0019 18.2 0.0 2.0 2 0 0 2 2 2 1 MIT (microtubule interacting and transport) domain Glyco_tranf_2_3 PF13641.6 OQR91117.1 - 0.037 13.9 0.0 0.082 12.8 0.0 1.6 1 0 0 1 1 1 0 Glycosyltransferase like family 2 Chitin_synth_1N PF08407.11 OQR91117.1 - 0.045 13.7 0.0 0.11 12.4 0.0 1.7 1 0 0 1 1 1 0 Chitin synthase N-terminal Ferric_reduct PF01794.19 OQR91118.1 - 4.7e-18 65.5 12.7 4.9e-18 65.4 8.3 2.9 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 OQR91118.1 - 6.3e-15 55.6 0.0 1.1e-14 54.8 0.0 1.4 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 OQR91118.1 - 2.7e-12 46.7 0.2 5.4e-12 45.8 0.2 1.5 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_1 PF00175.21 OQR91118.1 - 0.0013 19.3 0.1 0.0051 17.4 0.0 2.0 3 0 0 3 3 3 1 Oxidoreductase NAD-binding domain Rad9 PF04139.13 OQR91119.1 - 4e-47 160.8 1.9 4.8e-47 160.5 1.9 1.1 1 0 0 1 1 1 1 Rad9 DUF5091 PF17012.5 OQR91119.1 - 0.00074 19.8 0.1 0.0025 18.1 0.0 1.9 3 0 0 3 3 3 1 Domain of unknown function (DUF5091) XPG_N PF00752.17 OQR91119.1 - 0.14 12.6 0.0 0.38 11.2 0.0 1.7 1 0 0 1 1 1 0 XPG N-terminal domain RIBIOP_C PF04950.12 OQR91120.1 - 1.8e-93 313.2 3.9 3.4e-93 312.3 0.1 2.3 2 0 0 2 2 2 1 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal cNMP_binding PF00027.29 OQR91120.1 - 2.6e-27 94.7 0.7 2.1e-12 47.0 0.1 5.0 4 1 0 4 4 4 2 Cyclic nucleotide-binding domain RGS PF00615.19 OQR91120.1 - 0.025 14.8 0.1 0.11 12.7 0.1 2.2 2 0 0 2 2 2 0 Regulator of G protein signaling domain MIP PF00230.20 OQR91132.1 - 1.3e-51 175.5 9.7 1.7e-51 175.1 9.7 1.0 1 0 0 1 1 1 1 Major intrinsic protein ADK PF00406.22 OQR91136.1 - 1.3e-52 177.9 0.0 2.6e-34 118.5 0.0 3.2 3 0 0 3 3 3 2 Adenylate kinase BT1 PF03092.16 OQR91136.1 - 4.7e-41 140.6 20.6 4.5e-26 91.2 4.2 2.8 1 1 2 3 3 3 2 BT1 family AAA_17 PF13207.6 OQR91136.1 - 7.9e-24 84.6 0.0 1.6e-16 61.0 0.0 2.6 2 0 0 2 2 2 2 AAA domain MFS_1 PF07690.16 OQR91136.1 - 2e-08 33.6 44.0 2.9e-07 29.7 26.6 2.7 1 1 2 3 3 3 2 Major Facilitator Superfamily AAA_18 PF13238.6 OQR91136.1 - 4e-06 27.4 0.0 7.3e-05 23.3 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 OQR91136.1 - 0.011 15.9 0.0 0.043 14.0 0.0 2.0 1 0 0 1 1 1 0 AAA domain Hydin_ADK PF17213.3 OQR91136.1 - 0.59 10.4 6.6 8.5 6.6 0.2 3.8 4 0 0 4 4 4 0 Hydin Adenylate kinase-like domain Ribosomal_L3 PF00297.22 OQR91137.1 - 1.4e-180 600.1 7.8 1.6e-180 600.0 7.8 1.0 1 0 0 1 1 1 1 Ribosomal protein L3 Skp1 PF01466.19 OQR91138.1 - 5.3e-28 96.9 0.7 9.8e-28 96.0 0.7 1.5 1 0 0 1 1 1 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.15 OQR91138.1 - 1.7e-23 82.5 0.3 3.2e-23 81.7 0.3 1.4 1 0 0 1 1 1 1 Skp1 family, tetramerisation domain BTB PF00651.31 OQR91138.1 - 0.00063 20.0 0.1 0.0029 17.8 0.1 1.9 1 1 0 1 1 1 1 BTB/POZ domain Forkhead PF00250.18 OQR91146.1 - 2.9e-07 30.6 2.0 3.1e-07 30.6 0.5 1.8 2 1 0 2 2 2 1 Forkhead domain PHD PF00628.29 OQR91146.1 - 1.1e-06 28.4 8.3 2.2e-06 27.5 8.3 1.5 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.6 OQR91146.1 - 0.00089 19.5 3.5 0.0021 18.3 3.5 1.6 1 0 0 1 1 1 1 PHD-like zinc-binding domain Linker_histone PF00538.19 OQR91146.1 - 0.059 13.8 0.0 0.1 13.0 0.0 1.5 1 0 0 1 1 1 0 linker histone H1 and H5 family zf-HC5HC2H_2 PF13832.6 OQR91146.1 - 0.11 12.7 4.1 0.12 12.6 2.7 1.8 1 1 1 2 2 2 0 PHD-zinc-finger like domain NOG1_N PF17835.1 OQR91147.1 - 7.5e-55 185.3 1.1 7.5e-55 185.3 1.1 2.5 3 0 0 3 3 3 1 NOG1 N-terminal helical domain NOG1 PF06858.14 OQR91147.1 - 9.1e-27 92.6 0.7 1.7e-26 91.7 0.1 1.8 2 0 0 2 2 2 1 Nucleolar GTP-binding protein 1 (NOG1) NOGCT PF08155.11 OQR91147.1 - 4.3e-25 87.5 1.3 1e-24 86.3 1.3 1.7 1 0 0 1 1 1 1 NOGCT (NUC087) domain MMR_HSR1 PF01926.23 OQR91147.1 - 6.1e-17 61.7 0.0 1.4e-16 60.6 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 OQR91147.1 - 5.1e-09 35.8 0.0 8.7e-09 35.1 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B AAA_16 PF13191.6 OQR91147.1 - 0.064 13.6 0.3 0.45 10.9 0.0 2.4 2 1 0 2 2 2 0 AAA ATPase domain Dynamin_N PF00350.23 OQR91147.1 - 0.68 10.0 4.6 5.8 6.9 0.0 3.1 3 1 1 4 4 4 0 Dynamin family BPL_LplA_LipB PF03099.19 OQR91148.1 - 4.6e-08 33.0 0.0 7.9e-08 32.3 0.0 1.4 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family RINGv PF12906.7 OQR91149.1 - 0.0002 21.4 2.3 0.00032 20.8 2.3 1.5 1 1 0 1 1 1 1 RING-variant domain Histone PF00125.24 OQR91152.1 - 3.3e-52 176.3 2.6 3.7e-52 176.2 2.6 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 OQR91152.1 - 9.5e-05 22.7 0.1 0.00014 22.1 0.1 1.2 1 0 0 1 1 1 1 CENP-S protein PAF PF15715.5 OQR91152.1 - 0.00022 21.8 1.2 0.00027 21.5 1.2 1.1 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CENP-T_C PF15511.6 OQR91152.1 - 0.0005 20.2 0.1 0.00099 19.2 0.1 1.5 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TFIID-31kDa PF02291.15 OQR91152.1 - 0.035 14.2 0.4 0.059 13.4 0.1 1.5 2 0 0 2 2 2 0 Transcription initiation factor IID, 31kD subunit CBFD_NFYB_HMF PF00808.23 OQR91152.1 - 0.052 13.8 0.1 0.099 12.9 0.1 1.5 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone RINGv PF12906.7 OQR91154.1 - 2.3e-07 30.8 8.3 3.9e-07 30.1 8.3 1.4 1 0 0 1 1 1 1 RING-variant domain zf-RING_2 PF13639.6 OQR91154.1 - 1.9e-06 28.1 8.9 3.3e-06 27.3 8.9 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_4 PF14570.6 OQR91154.1 - 0.0025 17.6 5.6 0.004 16.9 5.6 1.4 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-ANAPC11 PF12861.7 OQR91154.1 - 0.0067 16.5 1.2 0.016 15.3 1.2 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.6 OQR91154.1 - 0.041 13.7 6.3 0.083 12.8 6.3 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-UDP PF14569.6 OQR91154.1 - 0.048 13.8 1.8 0.083 13.0 1.8 1.4 1 0 0 1 1 1 0 Zinc-binding RING-finger DUF3185 PF11381.8 OQR91154.1 - 0.09 12.8 0.5 0.09 12.8 0.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3185) Zn_ribbon_17 PF17120.5 OQR91154.1 - 0.094 12.4 6.7 0.18 11.5 6.7 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type PHD PF00628.29 OQR91154.1 - 0.14 12.0 6.9 0.24 11.3 6.9 1.4 1 0 0 1 1 1 0 PHD-finger FANCL_C PF11793.8 OQR91154.1 - 0.25 11.5 4.8 0.54 10.5 4.8 1.6 1 0 0 1 1 1 0 FANCL C-terminal domain zf-rbx1 PF12678.7 OQR91154.1 - 0.26 11.6 5.8 0.47 10.8 5.8 1.5 1 0 0 1 1 1 0 RING-H2 zinc finger domain Prok-RING_4 PF14447.6 OQR91154.1 - 0.88 9.5 5.1 1.8 8.5 5.1 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 Internalin_N PF12354.8 OQR91154.1 - 1.4 9.0 4.4 15 5.7 0.1 2.6 3 0 0 3 3 3 0 Bacterial adhesion/invasion protein N terminal Yip1 PF04893.17 OQR91154.1 - 2.1 8.0 13.0 3.2 7.4 13.0 1.2 1 0 0 1 1 1 0 Yip1 domain zf-C3HC4 PF00097.25 OQR91154.1 - 2.4 8.1 8.8 4.7 7.2 8.8 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) CRPA PF05745.11 OQR91154.1 - 6.7 6.7 8.3 0.48 10.4 2.8 1.9 2 0 0 2 2 2 0 Chlamydia 15 kDa cysteine-rich outer membrane protein (CRPA) DUF1980 PF09323.10 OQR91154.1 - 7.1 6.5 5.6 14 5.5 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1980) zf-C3HC4_2 PF13923.6 OQR91154.1 - 9.5 6.2 8.6 28 4.7 8.6 1.8 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DnaJ PF00226.31 OQR91155.1 - 2.9e-05 24.1 0.0 0.00014 21.9 0.0 2.2 1 0 0 1 1 1 1 DnaJ domain DUF5357 PF17310.2 OQR91155.1 - 1.2 7.6 4.9 2.2 6.8 4.9 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5357) Pkinase_Tyr PF07714.17 OQR91156.1 - 3.3e-40 138.0 0.0 3.6e-40 137.9 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OQR91156.1 - 8e-36 123.7 0.0 9.4e-36 123.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 OQR91156.1 - 0.00077 18.3 0.0 0.00093 18.1 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 OQR91156.1 - 0.047 13.6 0.0 0.067 13.1 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kinase-like PF14531.6 OQR91156.1 - 0.077 12.3 0.0 0.089 12.1 0.0 1.2 1 0 0 1 1 1 0 Kinase-like EI24 PF07264.11 OQR91159.1 - 0.0028 17.9 3.4 0.0036 17.6 3.4 1.1 1 0 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) Ceramidase PF05875.12 OQR91159.1 - 0.021 14.3 2.0 0.075 12.5 0.0 2.0 2 0 0 2 2 2 0 Ceramidase DUF3592 PF12158.8 OQR91159.1 - 0.098 12.7 1.5 0.3 11.2 0.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3592) DUF2207 PF09972.9 OQR91159.1 - 0.12 11.1 0.7 0.14 10.9 0.7 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) SecE PF00584.20 OQR91159.1 - 0.19 11.6 0.1 0.19 11.6 0.1 2.6 2 1 0 2 2 2 0 SecE/Sec61-gamma subunits of protein translocation complex HemY_N PF07219.13 OQR91159.1 - 0.53 10.5 3.0 0.76 10.0 0.7 2.0 2 0 0 2 2 2 0 HemY protein N-terminus DUF3487 PF11990.8 OQR91159.1 - 5.6 6.9 8.9 1.3 8.9 0.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3487) HA PF03457.14 OQR91160.1 - 3e-23 81.9 1.2 2e-08 34.4 0.0 3.8 4 0 0 4 4 4 3 Helicase associated domain RINGv PF12906.7 OQR91162.1 - 0.0012 18.9 11.6 0.0012 18.9 11.6 2.3 2 0 0 2 2 2 1 RING-variant domain Peptidase_M48_N PF16491.5 OQR91162.1 - 0.46 10.4 0.1 0.46 10.4 0.1 2.8 3 0 0 3 3 3 0 CAAX prenyl protease N-terminal, five membrane helices DUF1218 PF06749.12 OQR91162.1 - 2.4 8.7 9.1 6.9 7.3 6.5 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1218) ABC2_membrane_3 PF12698.7 OQR91162.1 - 7.3 5.6 6.9 14 4.7 6.9 1.4 1 0 0 1 1 1 0 ABC-2 family transporter protein LapA_dom PF06305.11 OQR91162.1 - 9.1 6.2 9.8 8.7 6.3 0.9 3.1 3 0 0 3 3 3 0 Lipopolysaccharide assembly protein A domain Sel1 PF08238.12 OQR91163.1 - 4.5e-37 125.7 37.7 3.5e-05 24.3 0.1 11.8 11 1 0 11 11 11 10 Sel1 repeat TPR_17 PF13431.6 OQR91163.1 - 0.015 15.6 0.4 22 5.7 0.2 5.1 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.28 OQR91163.1 - 2.5 8.1 18.1 8.4 6.4 0.1 6.4 6 0 0 6 6 6 0 Tetratricopeptide repeat CpXC PF14353.6 OQR91177.1 - 2 8.5 15.2 0.11 12.5 2.4 3.1 2 1 1 3 3 3 0 CpXC protein cNMP_binding PF00027.29 OQR91178.1 - 3.9e-15 55.7 0.0 3.2e-13 49.6 0.0 2.2 1 1 0 1 1 1 1 Cyclic nucleotide-binding domain ZZ PF00569.17 OQR91179.1 - 5.8e-09 35.6 10.7 1.2e-08 34.6 10.7 1.6 1 0 0 1 1 1 1 Zinc finger, ZZ type F-box-like PF12937.7 OQR91179.1 - 1.2e-07 31.4 0.2 3.8e-07 29.9 0.2 1.9 1 0 0 1 1 1 1 F-box-like USP7_ICP0_bdg PF12436.8 OQR91179.1 - 3.2e-06 26.7 0.0 8.4e-05 22.0 0.0 2.1 2 0 0 2 2 2 1 ICP0-binding domain of Ubiquitin-specific protease 7 F-box PF00646.33 OQR91179.1 - 6.1e-06 26.0 0.0 1.6e-05 24.7 0.0 1.8 1 0 0 1 1 1 1 F-box domain GramPos_pilinD1 PF16555.5 OQR91179.1 - 0.17 12.0 0.0 0.41 10.8 0.0 1.6 1 0 0 1 1 1 0 Gram-positive pilin subunit D1, N-terminal domain Mito_carr PF00153.27 OQR91197.1 - 1.4e-59 198.1 4.8 7.4e-21 73.9 0.1 3.8 3 0 0 3 3 3 3 Mitochondrial carrier protein Metallophos PF00149.28 OQR91197.1 - 2.2e-39 136.1 0.1 4e-39 135.2 0.1 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Foie-gras_1 PF11817.8 OQR91197.1 - 1e-24 87.5 4.6 1.9e-24 86.7 4.6 1.5 1 0 0 1 1 1 1 Foie gras liver health family 1 RabGAP-TBC PF00566.18 OQR91197.1 - 6.6e-23 81.5 1.0 1.9e-22 80.0 1.0 1.9 1 1 0 1 1 1 1 Rab-GTPase-TBC domain STPPase_N PF16891.5 OQR91197.1 - 1.5e-13 51.0 0.1 3.9e-13 49.6 0.1 1.7 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain PH PF00169.29 OQR91197.1 - 9.3e-05 22.9 0.0 0.00056 20.4 0.0 2.4 1 0 0 1 1 1 1 PH domain TRAPPC10 PF12584.8 OQR91197.1 - 0.006 16.3 0.0 0.015 15.0 0.0 1.6 1 0 0 1 1 1 1 Trafficking protein particle complex subunit 10, TRAPPC10 Gryzun-like PF12742.7 OQR91197.1 - 0.018 15.0 0.0 0.062 13.3 0.0 1.9 1 0 0 1 1 1 0 Gryzun, putative Golgi trafficking DUF2299 PF10061.9 OQR91197.1 - 0.26 11.0 1.5 0.44 10.3 0.3 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2299) MS_channel PF00924.18 OQR91198.1 - 4.6e-28 98.2 0.1 6.9e-28 97.6 0.1 1.3 1 0 0 1 1 1 1 Mechanosensitive ion channel Sec62 PF03839.16 OQR91198.1 - 0.2 11.1 1.7 0.47 9.9 1.7 1.6 1 0 0 1 1 1 0 Translocation protein Sec62 PEX11 PF05648.14 OQR91199.1 - 2.4e-08 33.7 10.6 3.8e-08 33.1 6.6 2.7 1 1 1 2 2 2 1 Peroxisomal biogenesis factor 11 (PEX11) FOXP-CC PF16159.5 OQR91199.1 - 2.7 8.7 17.6 0.63 10.7 1.8 4.3 2 2 2 4 4 4 0 FOXP coiled-coil domain CxC6 PF18721.1 OQR91200.1 - 0.01 16.1 33.1 0.053 13.8 7.7 3.5 1 1 2 3 3 3 0 CxC6 like cysteine cluster associated with KDZ transposases ATP-synt_ab PF00006.25 OQR91209.1 - 2.5e-28 99.2 0.0 4e-28 98.5 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 OQR91209.1 - 0.0047 17.4 0.0 0.012 16.1 0.0 1.7 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain AAA PF00004.29 OQR91209.1 - 0.028 14.8 0.0 0.068 13.6 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 OQR91209.1 - 0.059 13.7 0.0 0.13 12.6 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain ATPase PF06745.13 OQR91209.1 - 0.066 12.6 0.0 0.099 12.0 0.0 1.3 1 0 0 1 1 1 0 KaiC ABC_tran PF00005.27 OQR91209.1 - 0.071 13.6 0.0 0.21 12.1 0.0 1.8 1 0 0 1 1 1 0 ABC transporter PMP1_2 PF08114.11 OQR91216.1 - 0.18 11.6 0.9 0.31 10.8 0.1 1.8 2 0 0 2 2 2 0 ATPase proteolipid family Glycophorin_A PF01102.18 OQR91217.1 - 5.4e-05 23.4 0.5 5.4e-05 23.4 0.5 2.8 2 2 1 3 3 3 1 Glycophorin A TMEM154 PF15102.6 OQR91217.1 - 0.00081 19.3 0.1 0.00081 19.3 0.1 3.4 2 2 1 3 3 3 1 TMEM154 protein family CD34_antigen PF06365.12 OQR91217.1 - 0.0013 18.3 0.0 0.0025 17.4 0.0 1.4 1 0 0 1 1 1 1 CD34/Podocalyxin family Adeno_E3_CR2 PF02439.15 OQR91217.1 - 0.0015 18.2 3.6 0.0028 17.4 3.6 1.4 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 Shisa PF13908.6 OQR91217.1 - 0.0034 17.7 6.5 0.0034 17.7 6.5 3.6 1 1 3 4 4 4 1 Wnt and FGF inhibitory regulator Podoplanin PF05808.11 OQR91217.1 - 0.011 15.9 12.7 0.011 15.9 12.7 2.1 1 1 1 2 2 2 0 Podoplanin Chordopox_A13L PF05961.11 OQR91217.1 - 0.056 13.7 0.2 0.32 11.2 0.0 2.3 2 0 0 2 2 2 0 Chordopoxvirus A13L protein Syndecan PF01034.20 OQR91217.1 - 0.099 12.6 0.1 0.42 10.6 0.1 2.0 1 0 0 1 1 1 0 Syndecan domain Insulin_TMD PF17870.1 OQR91217.1 - 0.1 12.7 0.1 0.19 11.8 0.1 1.4 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment DUF5305 PF17231.2 OQR91217.1 - 0.12 11.7 0.1 0.24 10.8 0.1 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5305) EF-hand_6 PF13405.6 OQR91218.1 - 3.6e-05 23.3 2.1 0.0016 18.2 0.0 3.2 3 0 0 3 3 3 1 EF-hand domain EF-hand_1 PF00036.32 OQR91218.1 - 0.0002 20.7 0.2 0.033 13.8 0.0 2.8 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 OQR91218.1 - 0.019 15.4 0.7 0.11 13.0 0.2 2.5 2 0 0 2 2 2 0 EF-hand domain pair WI12 PF07107.11 OQR91218.1 - 0.06 13.5 0.0 0.12 12.5 0.0 1.4 1 0 0 1 1 1 0 Wound-induced protein WI12 Guanylate_cyc PF00211.20 OQR91219.1 - 2.8e-97 323.7 0.4 2.5e-49 167.4 0.0 2.4 2 0 0 2 2 2 2 Adenylate and Guanylate cyclase catalytic domain DAO PF01266.24 OQR91219.1 - 1.8e-45 156.1 0.0 3.3e-45 155.2 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 OQR91219.1 - 0.0029 16.4 0.7 0.05 12.3 0.1 2.2 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_2 PF07992.14 OQR91219.1 - 0.022 14.0 0.1 2.7 7.1 0.1 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HNOBA PF07701.14 OQR91219.1 - 0.078 12.4 0.4 7.3 6.0 0.1 2.4 2 0 0 2 2 2 0 Heme NO binding associated Pyr_redox_3 PF13738.6 OQR91219.1 - 0.094 12.0 2.5 0.082 12.1 0.1 2.1 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.16 OQR91219.1 - 0.13 11.9 0.2 0.26 10.9 0.2 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA 3HCDH_N PF02737.18 OQR91219.1 - 0.13 12.1 0.1 0.26 11.2 0.1 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF2107 PF09880.9 OQR91219.1 - 0.34 11.0 5.3 1.7 8.8 5.3 2.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2107) zf-C2H2_2 PF12756.7 OQR91227.1 - 1.3e-30 105.7 22.6 2.3e-27 95.3 5.2 3.5 4 0 0 4 4 4 3 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.8 OQR91227.1 - 0.00059 20.0 6.8 0.00059 20.0 6.8 4.0 3 1 0 3 3 3 1 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.26 OQR91227.1 - 0.0012 19.1 25.5 0.0022 18.3 3.0 4.7 4 0 0 4 4 4 2 Zinc finger, C2H2 type zf-C2HC_2 PF13913.6 OQR91227.1 - 0.003 17.4 0.2 0.0096 15.8 0.2 1.9 1 0 0 1 1 1 1 zinc-finger of a C2HC-type zf-C2H2_6 PF13912.6 OQR91227.1 - 0.004 17.1 3.2 0.004 17.1 3.2 3.8 3 0 0 3 3 3 1 C2H2-type zinc finger zf-C2H2_4 PF13894.6 OQR91227.1 - 0.015 16.1 1.1 0.015 16.1 1.1 4.7 5 0 0 5 5 5 0 C2H2-type zinc finger FYDLN_acid PF09538.10 OQR91227.1 - 0.16 12.7 11.5 0.48 11.1 3.2 3.0 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) zf-met PF12874.7 OQR91227.1 - 2.6 8.6 10.5 0.98 9.9 6.3 2.5 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_3rep PF18868.1 OQR91227.1 - 3.5 8.3 10.5 1.2 9.8 0.3 4.2 2 2 1 4 4 4 0 Zinc finger C2H2-type, 3 repeats zf-LYAR PF08790.11 OQR91227.1 - 6.6 6.7 9.4 4.8 7.2 0.4 3.1 3 0 0 3 3 3 0 LYAR-type C2HC zinc finger Cadherin_C_2 PF16492.5 OQR91230.1 - 0.014 16.1 0.1 0.29 11.9 0.0 2.9 2 0 0 2 2 2 0 Cadherin cytoplasmic C-terminal CBM64 PF18666.1 OQR91230.1 - 0.088 12.9 0.4 0.29 11.2 0.4 1.8 1 0 0 1 1 1 0 Carbohydrate-binding module 64 Methyltransf_16 PF10294.9 OQR91231.1 - 3.3e-22 79.0 0.1 4.8e-22 78.5 0.1 1.1 1 0 0 1 1 1 1 Lysine methyltransferase MTS PF05175.14 OQR91231.1 - 0.02 14.4 0.0 0.03 13.9 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain EF-hand_1 PF00036.32 OQR91232.1 - 5.8e-13 47.4 7.3 0.00017 20.9 0.1 4.6 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.6 OQR91232.1 - 7.2e-11 41.1 5.6 0.017 15.0 0.1 4.7 4 0 0 4 4 4 3 EF-hand domain EF-hand_7 PF13499.6 OQR91232.1 - 9e-11 42.1 5.7 6.3e-05 23.4 0.8 3.5 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 OQR91232.1 - 5.8e-09 35.0 3.0 0.016 14.7 0.1 4.4 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.6 OQR91232.1 - 1.4e-05 24.8 7.9 0.97 9.3 0.2 4.3 4 0 0 4 4 4 3 EF-hand domain pair EF-hand_4 PF12763.7 OQR91232.1 - 0.0081 16.1 0.6 0.33 10.9 0.0 2.6 1 1 1 2 2 2 1 Cytoskeletal-regulatory complex EF hand Yip1 PF04893.17 OQR91251.1 - 1.5e-10 41.1 11.6 2.1e-10 40.6 11.6 1.2 1 0 0 1 1 1 1 Yip1 domain Kinesin PF00225.23 OQR91252.1 - 2.5e-79 266.7 0.3 4.3e-79 265.9 0.3 1.4 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 OQR91252.1 - 3.8e-14 52.9 0.4 8.4e-14 51.7 0.0 1.8 2 0 0 2 2 2 1 Microtubule binding AAA_16 PF13191.6 OQR91252.1 - 0.0049 17.3 0.1 0.062 13.7 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain AAA_30 PF13604.6 OQR91252.1 - 0.02 14.6 0.1 2 8.1 0.1 2.4 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 OQR91252.1 - 0.037 14.4 0.2 0.38 11.1 0.1 2.5 2 0 0 2 2 2 0 RNA helicase AAA_22 PF13401.6 OQR91252.1 - 0.067 13.5 0.2 0.26 11.6 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 OQR91252.1 - 0.12 12.8 0.0 0.97 9.9 0.0 2.2 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) DUF87 PF01935.17 OQR91252.1 - 0.2 11.7 1.4 0.38 10.8 0.0 2.1 3 0 0 3 3 3 0 Helicase HerA, central domain Ank_5 PF13857.6 OQR91253.1 - 1.3e-21 76.4 5.2 1e-11 44.8 0.1 4.2 3 2 2 5 5 4 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 OQR91253.1 - 2.2e-16 60.0 1.2 5.4e-06 26.8 0.1 3.5 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 OQR91253.1 - 2.5e-15 56.8 0.1 3e-07 30.9 0.0 3.1 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OQR91253.1 - 2.1e-14 52.2 2.6 0.00043 20.5 0.0 5.0 5 0 0 5 5 5 2 Ankyrin repeat Ank PF00023.30 OQR91253.1 - 5.9e-12 45.5 2.5 0.00029 21.2 0.1 4.2 5 0 0 5 5 4 2 Ankyrin repeat zf-C3HC4_3 PF13920.6 OQR91253.1 - 2.6e-07 30.4 12.3 2.6e-07 30.4 12.3 2.2 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) Rsa3 PF14615.6 OQR91253.1 - 0.04 13.5 0.0 12 5.6 0.0 2.3 2 0 0 2 2 2 0 Ribosome-assembly protein 3 zf-C3HC4_2 PF13923.6 OQR91253.1 - 0.093 12.6 20.6 0.038 13.8 15.5 2.4 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) DUF2039 PF10217.9 OQR91253.1 - 0.24 11.8 7.2 0.49 10.8 7.2 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2039) zf-RING_4 PF14570.6 OQR91253.1 - 1.5 8.7 10.8 4.3 7.2 10.8 1.8 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-C3HC4 PF00097.25 OQR91253.1 - 1.6 8.7 21.3 0.25 11.2 16.3 2.1 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) AAA_26 PF13500.6 OQR91254.1 - 2.2e-43 148.4 0.0 3.1e-43 147.9 0.0 1.2 1 0 0 1 1 1 1 AAA domain DRTGG PF07085.12 OQR91254.1 - 7.3e-07 28.9 0.0 1.4e-06 28.0 0.0 1.4 1 0 0 1 1 1 1 DRTGG domain CbiA PF01656.23 OQR91254.1 - 0.0012 18.9 0.0 0.0029 17.7 0.0 1.6 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain Gly_reductase PF09338.11 OQR91254.1 - 0.12 10.7 0.2 0.19 10.1 0.2 1.2 1 0 0 1 1 1 0 Glycine/sarcosine/betaine reductase component B subunits AA_permease_2 PF13520.6 OQR91269.1 - 5.7e-50 170.4 47.1 9.3e-50 169.7 47.1 1.3 1 1 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 OQR91269.1 - 2e-08 33.3 41.6 3.3e-08 32.6 41.6 1.3 1 0 0 1 1 1 1 Amino acid permease Gluconate_2-dh3 PF13618.6 OQR91271.1 - 8.6 6.6 11.1 51 4.1 11.1 2.4 1 1 0 1 1 1 0 Gluconate 2-dehydrogenase subunit 3 SspH PF08141.12 OQR91273.1 - 0.045 13.9 1.4 3.1 8.0 1.2 2.3 2 0 0 2 2 2 0 Small acid-soluble spore protein H family NUC205 PF08168.11 OQR91273.1 - 2.5 7.7 3.8 1.9 8.1 0.1 2.4 2 0 0 2 2 2 0 NUC205 domain FAD_binding_3 PF01494.19 OQR91274.1 - 3e-65 220.8 0.0 3.8e-65 220.4 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 OQR91274.1 - 0.064 12.8 0.3 1.7 8.1 0.1 2.8 1 1 1 2 2 2 0 FAD dependent oxidoreductase SKIP_SNW PF02731.15 OQR91275.1 - 2.4e-66 222.3 1.2 2.4e-66 222.3 1.2 2.3 2 0 0 2 2 2 1 SKIP/SNW domain Cwf_Cwc_15 PF04889.12 OQR91275.1 - 9.5 5.9 35.3 0.079 12.7 17.2 2.3 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein ABC_tran PF00005.27 OQR91283.1 - 1e-31 110.2 0.0 2.1e-31 109.2 0.0 1.5 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.23 OQR91283.1 - 2e-23 83.4 12.3 2e-23 83.4 12.3 1.9 2 0 0 2 2 2 1 ABC transporter transmembrane region SMC_N PF02463.19 OQR91283.1 - 4.8e-08 32.7 0.1 8.1e-06 25.4 0.1 2.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 OQR91283.1 - 2.9e-06 27.8 0.0 1.3e-05 25.7 0.0 2.1 1 0 0 1 1 1 1 AAA ATPase domain AAA PF00004.29 OQR91283.1 - 0.00079 19.9 0.1 0.71 10.3 0.0 2.7 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 OQR91283.1 - 0.0008 19.7 1.9 0.0068 16.7 0.4 2.7 2 1 0 2 2 1 1 AAA domain RNA_helicase PF00910.22 OQR91283.1 - 0.00088 19.6 0.1 0.0036 17.7 0.1 2.1 1 0 0 1 1 1 1 RNA helicase RsgA_GTPase PF03193.16 OQR91283.1 - 0.003 17.5 0.0 0.0086 16.0 0.0 1.7 1 0 0 1 1 1 1 RsgA GTPase AAA_15 PF13175.6 OQR91283.1 - 0.0035 17.1 0.0 0.015 15.1 0.0 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_23 PF13476.6 OQR91283.1 - 0.0064 17.0 0.1 0.015 15.8 0.1 1.8 1 1 0 1 1 1 1 AAA domain AAA_21 PF13304.6 OQR91283.1 - 0.011 15.6 0.2 0.13 12.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 OQR91283.1 - 0.011 15.5 0.0 0.033 13.9 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_ATPase PF09818.9 OQR91283.1 - 0.017 14.0 0.1 0.3 9.8 0.1 2.2 2 0 0 2 2 2 0 Predicted ATPase of the ABC class ATP-synt_ab PF00006.25 OQR91283.1 - 0.027 14.1 0.1 0.13 11.9 0.0 2.1 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain SbcCD_C PF13558.6 OQR91283.1 - 0.033 14.4 0.2 0.16 12.2 0.2 2.2 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_5 PF07728.14 OQR91283.1 - 0.033 14.2 0.1 0.5 10.4 0.0 2.6 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) NACHT PF05729.12 OQR91283.1 - 0.039 13.9 0.1 0.11 12.3 0.0 1.9 2 0 0 2 2 1 0 NACHT domain AAA_14 PF13173.6 OQR91283.1 - 0.042 13.9 0.0 0.16 12.0 0.0 1.9 2 0 0 2 2 1 0 AAA domain AAA_30 PF13604.6 OQR91283.1 - 0.043 13.5 0.0 0.5 10.1 0.0 2.7 2 1 0 2 2 2 0 AAA domain Septin PF00735.18 OQR91283.1 - 0.063 12.6 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 Septin Rad17 PF03215.15 OQR91283.1 - 0.068 13.1 0.0 0.19 11.6 0.0 1.7 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_25 PF13481.6 OQR91283.1 - 0.1 12.1 0.0 0.5 9.9 0.0 2.0 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 OQR91283.1 - 0.14 12.2 0.0 0.6 10.2 0.0 2.1 2 0 0 2 2 2 0 50S ribosome-binding GTPase DUF5090 PF17009.5 OQR91285.1 - 0.036 14.0 2.7 0.052 13.5 2.7 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF5090) PIG-H PF10181.9 OQR91295.1 - 5e-15 55.1 0.5 8.2e-15 54.4 0.5 1.3 1 0 0 1 1 1 1 GPI-GlcNAc transferase complex, PIG-H component Surp PF01805.20 OQR91295.1 - 0.096 12.7 0.0 0.18 11.8 0.0 1.5 1 0 0 1 1 1 0 Surp module PhzC-PhzF PF02567.16 OQR91296.1 - 2.5e-53 181.4 0.0 2.9e-53 181.1 0.0 1.1 1 0 0 1 1 1 1 Phenazine biosynthesis-like protein Cyclin_N PF00134.23 OQR91297.1 - 9.4e-11 41.6 0.0 3.7e-10 39.6 0.0 2.1 1 1 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 OQR91297.1 - 4.1e-07 30.1 0.1 1.5e-06 28.3 0.0 2.0 2 0 0 2 2 2 1 Cyclin, C-terminal domain CCDC84 PF14968.6 OQR91298.1 - 2.1e-16 60.5 21.2 1.9e-13 50.8 13.2 3.2 1 1 1 2 2 2 2 Coiled coil protein 84 HHH_5 PF14520.6 OQR91302.1 - 0.00056 20.5 0.1 0.0016 19.0 0.0 1.8 2 0 0 2 2 2 1 Helix-hairpin-helix domain BAF PF02961.14 OQR91302.1 - 0.0013 19.1 0.1 0.0083 16.5 0.0 2.2 1 1 1 2 2 2 1 Barrier to autointegration factor IMS_HHH PF11798.8 OQR91302.1 - 0.021 15.1 0.0 0.043 14.2 0.0 1.6 1 1 0 1 1 1 0 IMS family HHH motif HHH PF00633.23 OQR91302.1 - 0.081 12.8 0.3 0.24 11.3 0.3 1.9 1 0 0 1 1 1 0 Helix-hairpin-helix motif Cyclase PF04199.13 OQR91302.1 - 0.097 12.9 0.0 0.55 10.5 0.0 1.9 2 0 0 2 2 2 0 Putative cyclase Glyco_hydro_3 PF00933.21 OQR91303.1 - 1.4e-56 192.2 0.0 1.9e-56 191.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.22 OQR91303.1 - 2.2e-39 135.6 0.0 3.9e-39 134.7 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.6 OQR91303.1 - 7.4e-11 42.0 0.0 1.4e-10 41.1 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain cNMP_binding PF00027.29 OQR91304.1 - 4.4e-09 36.3 0.0 7.7e-09 35.5 0.0 1.3 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Serine_protease PF18405.1 OQR91304.1 - 0.022 13.9 0.0 0.037 13.2 0.0 1.3 1 0 0 1 1 1 0 Gammaproteobacterial serine protease Sas10_Utp3 PF04000.15 OQR91305.1 - 1.3e-13 51.4 1.0 3.3e-13 50.1 0.1 2.2 2 0 0 2 2 2 1 Sas10/Utp3/C1D family eIF-3c_N PF05470.12 OQR91305.1 - 0.15 10.3 9.8 0.2 9.9 9.8 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus PI3K_1B_p101 PF10486.9 OQR91305.1 - 0.35 8.6 6.7 0.47 8.2 6.7 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit DUF4407 PF14362.6 OQR91305.1 - 1.5 8.1 8.5 2.2 7.6 8.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) UQ_con PF00179.26 OQR91306.1 - 2.1e-40 137.6 0.0 3e-40 137.1 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme DNA_pol_phi PF04931.13 OQR91306.1 - 0.0041 15.3 14.2 0.0048 15.1 14.2 1.2 1 0 0 1 1 1 1 DNA polymerase phi TLP-20 PF06088.11 OQR91306.1 - 0.0094 15.9 10.4 0.013 15.3 10.4 1.2 1 0 0 1 1 1 1 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) PPP4R2 PF09184.11 OQR91306.1 - 0.016 14.8 12.7 0.02 14.5 12.7 1.1 1 0 0 1 1 1 0 PPP4R2 NOA36 PF06524.12 OQR91306.1 - 0.05 12.9 16.0 0.063 12.6 16.0 1.1 1 0 0 1 1 1 0 NOA36 protein Sporozoite_P67 PF05642.11 OQR91306.1 - 0.24 9.5 6.0 0.26 9.3 6.0 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DUF913 PF06025.12 OQR91306.1 - 0.28 10.1 5.7 0.34 9.8 5.7 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) RNA_pol_Rpc4 PF05132.14 OQR91306.1 - 0.36 11.3 3.2 0.44 11.0 3.2 1.2 1 0 0 1 1 1 0 RNA polymerase III RPC4 Cwf_Cwc_15 PF04889.12 OQR91306.1 - 0.42 10.3 17.8 0.59 9.8 17.8 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Nop14 PF04147.12 OQR91306.1 - 0.53 8.4 19.5 0.61 8.2 19.5 1.1 1 0 0 1 1 1 0 Nop14-like family DUF2457 PF10446.9 OQR91306.1 - 0.58 9.2 21.0 0.76 8.8 21.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) SDA1 PF05285.12 OQR91306.1 - 0.76 9.1 19.7 0.9 8.9 19.7 1.1 1 0 0 1 1 1 0 SDA1 RXT2_N PF08595.11 OQR91306.1 - 1.2 9.1 12.2 2 8.4 12.2 1.4 1 0 0 1 1 1 0 RXT2-like, N-terminal Afi1 PF07792.12 OQR91306.1 - 1.5 9.3 11.7 2.4 8.7 11.7 1.2 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking CDC45 PF02724.14 OQR91306.1 - 2.9 6.1 16.9 3.3 5.9 16.9 1.1 1 0 0 1 1 1 0 CDC45-like protein CobT PF06213.12 OQR91306.1 - 3.1 7.1 18.0 4.1 6.7 18.0 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT FAM60A PF15396.6 OQR91306.1 - 8.7 6.3 9.0 12 5.8 9.0 1.1 1 0 0 1 1 1 0 Protein Family FAM60A PseudoU_synth_1 PF01416.20 OQR91307.1 - 2.9e-19 69.5 0.0 6.7e-15 55.5 0.0 2.2 2 0 0 2 2 2 2 tRNA pseudouridine synthase MetW PF07021.12 OQR91307.1 - 0.011 15.4 0.0 0.016 14.8 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW ThiF PF00899.21 OQR91308.1 - 1.6e-38 132.4 0.1 2.6e-38 131.7 0.1 1.3 1 0 0 1 1 1 1 ThiF family Sacchrp_dh_NADP PF03435.18 OQR91308.1 - 0.0034 17.6 1.4 0.014 15.6 1.4 2.0 1 1 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain UDPG_MGDP_dh_N PF03721.14 OQR91308.1 - 0.0068 16.0 0.0 0.013 15.1 0.0 1.5 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain ApbA PF02558.16 OQR91308.1 - 0.017 14.8 0.1 0.052 13.2 0.1 1.9 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA FAD_binding_3 PF01494.19 OQR91308.1 - 0.047 12.9 0.1 0.067 12.4 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain AlaDh_PNT_C PF01262.21 OQR91308.1 - 0.063 12.6 0.1 0.14 11.4 0.1 1.6 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain TrkA_N PF02254.18 OQR91308.1 - 0.071 13.4 0.0 0.23 11.7 0.0 1.9 1 0 0 1 1 1 0 TrkA-N domain 3HCDH_N PF02737.18 OQR91308.1 - 0.077 12.9 0.1 0.13 12.2 0.1 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.19 OQR91308.1 - 0.099 12.0 0.1 0.49 9.7 0.0 2.0 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain LRR_6 PF13516.6 OQR91309.1 - 1.5e-17 62.1 38.5 0.064 13.3 0.1 14.3 14 0 0 14 14 14 6 Leucine Rich repeat LRR_4 PF12799.7 OQR91309.1 - 7.8e-15 54.8 43.2 0.0014 19.0 2.3 9.9 3 1 9 12 12 12 9 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 OQR91309.1 - 7.5e-14 51.2 39.4 1.1e-05 25.1 0.5 8.4 6 2 6 12 12 12 5 Leucine rich repeat LRR_1 PF00560.33 OQR91309.1 - 0.38 11.5 50.7 2.3 9.1 1.2 12.9 13 4 0 13 13 13 0 Leucine Rich Repeat LRR_9 PF14580.6 OQR91309.1 - 0.44 10.0 12.4 1 8.8 0.9 4.5 1 1 4 5 5 5 0 Leucine-rich repeat WD40 PF00400.32 OQR91310.1 - 6.9e-10 39.4 16.3 0.0037 18.1 0.5 6.7 6 1 1 7 7 7 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OQR91310.1 - 9.2e-09 35.5 0.9 0.0027 18.0 0.0 4.8 3 2 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 OQR91310.1 - 0.00026 20.9 3.1 0.011 15.7 0.8 3.5 2 1 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A DENN PF02141.21 OQR91311.1 - 2.3e-54 184.2 6.4 5.2e-54 183.0 6.4 1.6 1 0 0 1 1 1 1 DENN (AEX-3) domain ArfGap PF01412.18 OQR91311.1 - 8.8e-27 93.5 0.8 2e-26 92.3 0.8 1.7 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf uDENN PF03456.18 OQR91311.1 - 1.2e-14 54.8 1.2 4e-14 53.1 1.2 2.0 1 0 0 1 1 1 1 uDENN domain dDENN PF03455.19 OQR91311.1 - 2.9e-08 33.6 4.4 2.9e-08 33.6 4.4 2.4 2 0 0 2 2 2 1 dDENN domain IQ PF00612.27 OQR91311.1 - 1.4e-05 24.5 19.6 0.0096 15.6 2.4 4.5 4 0 0 4 4 4 3 IQ calmodulin-binding motif DUF3490 PF11995.8 OQR91311.1 - 0.026 14.4 0.0 0.072 12.9 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF3490) DiS_P_DiS PF06750.13 OQR91311.1 - 0.041 14.0 0.2 0.12 12.5 0.2 1.7 1 0 0 1 1 1 0 Bacterial Peptidase A24 N-terminal domain Mei5 PF10376.9 OQR91311.1 - 0.55 10.1 2.9 1.1 9.1 2.9 1.4 1 0 0 1 1 1 0 Double-strand recombination repair protein FA_hydroxylase PF04116.13 OQR91312.1 - 2.6e-21 76.4 14.5 2.6e-21 76.4 14.5 1.7 2 1 1 3 3 3 1 Fatty acid hydroxylase superfamily DUF3278 PF11683.8 OQR91312.1 - 0.077 13.1 2.8 0.18 11.9 2.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3278) FAD_binding_6 PF00970.24 OQR91314.1 - 9.2e-35 119.0 0.0 1.4e-34 118.4 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 OQR91314.1 - 9.6e-07 29.4 0.0 1.8e-06 28.5 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_9 PF08021.11 OQR91314.1 - 0.0014 18.9 0.0 0.0051 17.0 0.0 1.8 1 1 0 1 1 1 1 Siderophore-interacting FAD-binding domain NAD_binding_6 PF08030.12 OQR91314.1 - 0.055 13.6 0.0 0.096 12.8 0.0 1.4 1 0 0 1 1 1 0 Ferric reductase NAD binding domain HSF_DNA-bind PF00447.17 OQR91341.1 - 8e-139 452.7 36.2 2.4e-26 92.2 1.5 6.5 6 0 0 6 6 6 6 HSF-type DNA-binding DUF812 PF05667.11 OQR91341.1 - 0.00055 19.0 20.7 0.0084 15.1 1.2 4.0 4 0 0 4 4 4 2 Protein of unknown function (DUF812) Seryl_tRNA_N PF02403.22 OQR91341.1 - 0.0066 16.7 17.1 0.052 13.8 0.5 5.1 5 1 0 5 5 5 2 Seryl-tRNA synthetase N-terminal domain DUF948 PF06103.11 OQR91341.1 - 0.043 14.1 17.0 2.6 8.4 0.3 5.2 5 0 0 5 5 5 0 Bacterial protein of unknown function (DUF948) Pathogen_betaC1 PF09593.10 OQR91341.1 - 0.085 12.8 0.2 0.24 11.3 0.2 1.7 1 0 0 1 1 1 0 Beta-satellite pathogenicity beta C1 protein DASH_Dam1 PF08653.10 OQR91341.1 - 0.11 12.3 9.7 3.2 7.6 0.1 4.6 4 0 0 4 4 4 0 DASH complex subunit Dam1 DarA_N PF18788.1 OQR91341.1 - 0.13 12.4 0.1 0.13 12.4 0.1 2.6 3 0 0 3 3 3 0 Defence against restriction A N-terminal Exonuc_VII_L PF02601.15 OQR91341.1 - 0.17 11.4 11.8 0.23 11.0 1.6 3.8 4 0 0 4 4 4 0 Exonuclease VII, large subunit Flu_NS2 PF00601.19 OQR91341.1 - 0.19 12.0 4.3 0.51 10.7 1.4 2.8 2 0 0 2 2 2 0 Influenza non-structural protein (NS2) PRP1_N PF06424.12 OQR91341.1 - 0.22 11.9 3.3 3.7 7.9 0.4 3.4 3 1 0 3 3 2 0 PRP1 splicing factor, N-terminal DUF4065 PF13274.6 OQR91341.1 - 0.3 12.0 7.4 1.3 10.0 0.1 4.0 4 0 0 4 4 3 0 Protein of unknown function (DUF4065) FlaC_arch PF05377.11 OQR91341.1 - 0.32 11.4 23.3 3.4 8.1 1.0 6.0 5 0 0 5 5 5 0 Flagella accessory protein C (FlaC) EDR1 PF14381.6 OQR91341.1 - 0.38 10.4 4.4 1.4 8.6 0.2 3.4 4 0 0 4 4 4 0 Ethylene-responsive protein kinase Le-CTR1 NPV_P10 PF05531.12 OQR91341.1 - 2.1 8.9 21.9 12 6.4 1.3 5.2 5 0 0 5 5 5 0 Nucleopolyhedrovirus P10 protein LXG PF04740.12 OQR91341.1 - 3.4 7.3 16.4 1.8 8.2 1.0 3.9 4 0 0 4 4 4 0 LXG domain of WXG superfamily DUF1664 PF07889.12 OQR91341.1 - 5.4 7.1 23.2 0.44 10.6 0.5 5.2 5 0 0 5 5 5 0 Protein of unknown function (DUF1664) BLOC1_2 PF10046.9 OQR91341.1 - 8.4 6.8 23.8 3.9 7.8 0.9 5.5 6 0 0 6 6 6 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 HSF_DNA-bind PF00447.17 OQR91342.1 - 1.1e-29 102.9 3.4 1.1e-29 102.9 3.4 1.9 2 0 0 2 2 2 1 HSF-type DNA-binding DUF812 PF05667.11 OQR91342.1 - 0.0019 17.2 1.9 0.0022 16.9 1.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF812) HAUS-augmin3 PF14932.6 OQR91342.1 - 0.0029 17.2 2.7 0.0044 16.6 2.7 1.3 1 0 0 1 1 1 1 HAUS augmin-like complex subunit 3 TSC22 PF01166.18 OQR91342.1 - 0.0029 17.9 1.9 0.0076 16.5 1.9 1.8 1 0 0 1 1 1 1 TSC-22/dip/bun family Baculo_PEP_C PF04513.12 OQR91342.1 - 0.0068 16.4 0.8 0.01 15.9 0.2 1.6 2 0 0 2 2 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus Dynamitin PF04912.14 OQR91342.1 - 0.0083 15.5 3.8 0.011 15.1 3.8 1.1 1 0 0 1 1 1 1 Dynamitin DUF5320 PF17253.2 OQR91342.1 - 0.011 16.7 0.2 0.023 15.8 0.2 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5320) Muted PF14942.6 OQR91342.1 - 0.019 15.3 4.0 0.036 14.4 4.0 1.4 1 0 0 1 1 1 0 Organelle biogenesis, Muted-like protein Sec23_trunk PF04811.15 OQR91342.1 - 0.021 14.4 0.5 2.5 7.6 0.0 2.4 2 1 0 2 2 2 0 Sec23/Sec24 trunk domain LPP PF04728.13 OQR91342.1 - 0.021 15.2 1.6 0.048 14.1 1.6 1.6 1 0 0 1 1 1 0 Lipoprotein leucine-zipper CENP-F_leu_zip PF10473.9 OQR91342.1 - 0.021 14.8 2.9 0.034 14.2 2.9 1.3 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 COG5 PF10392.9 OQR91342.1 - 0.024 14.8 0.8 0.058 13.6 0.8 1.7 1 0 0 1 1 1 0 Golgi transport complex subunit 5 DUF5082 PF16888.5 OQR91342.1 - 0.025 14.8 1.9 0.047 14.0 1.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5082) YlbD_coat PF14071.6 OQR91342.1 - 0.027 14.7 4.1 0.95 9.7 1.6 3.2 2 1 1 3 3 3 0 Putative coat protein Seryl_tRNA_N PF02403.22 OQR91342.1 - 0.028 14.7 0.5 0.055 13.7 0.5 1.5 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain Myosin_tail_1 PF01576.19 OQR91342.1 - 0.038 11.8 3.6 0.051 11.4 3.6 1.1 1 0 0 1 1 1 0 Myosin tail ANAPC4 PF12896.7 OQR91342.1 - 0.04 13.4 0.7 0.072 12.6 0.7 1.3 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 4 Sipho_Gp157 PF05565.11 OQR91342.1 - 0.045 13.8 2.0 0.085 12.9 2.0 1.4 1 0 0 1 1 1 0 Siphovirus Gp157 NPV_P10 PF05531.12 OQR91342.1 - 0.058 13.9 2.9 0.14 12.6 2.9 1.7 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein DUF2205 PF10224.9 OQR91342.1 - 0.059 13.4 0.6 0.12 12.4 0.6 1.6 1 0 0 1 1 1 0 Short coiled-coil protein Prefoldin PF02996.17 OQR91342.1 - 0.066 13.1 1.4 0.13 12.2 1.4 1.5 1 0 0 1 1 1 0 Prefoldin subunit CdiI_4 PF18624.1 OQR91342.1 - 0.072 13.6 1.7 0.078 13.5 0.5 1.7 2 0 0 2 2 1 0 CDI immunity protein Phage_GP20 PF06810.11 OQR91342.1 - 0.086 12.6 2.8 0.13 12.1 2.8 1.2 1 0 0 1 1 1 0 Phage minor structural protein GP20 FlxA PF14282.6 OQR91342.1 - 0.091 12.8 7.9 0.12 12.4 6.2 1.8 1 1 1 2 2 2 0 FlxA-like protein PRKG1_interact PF15898.5 OQR91342.1 - 0.13 13.1 2.7 0.23 12.4 2.7 1.4 1 0 0 1 1 1 0 cGMP-dependent protein kinase interacting domain DUF4988 PF16378.5 OQR91342.1 - 0.17 11.5 1.4 0.22 11.2 0.5 1.6 2 0 0 2 2 2 0 Domain of unknown function SlyX PF04102.12 OQR91342.1 - 0.17 12.5 2.2 0.36 11.5 2.2 1.5 1 0 0 1 1 1 0 SlyX ADIP PF11559.8 OQR91342.1 - 0.2 11.8 3.3 0.29 11.2 3.3 1.3 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding DUF3450 PF11932.8 OQR91342.1 - 0.23 10.7 5.3 0.35 10.1 5.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) V_ATPase_I PF01496.19 OQR91342.1 - 0.29 9.0 6.2 0.077 10.9 1.6 1.8 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family SLX9 PF15341.6 OQR91342.1 - 1.5 9.2 6.2 0.88 10.0 2.5 2.2 3 0 0 3 3 2 0 Ribosome biogenesis protein SLX9 HSF_DNA-bind PF00447.17 OQR91343.1 - 1.2e-31 109.1 3.0 2.4e-31 108.2 3.0 1.5 1 0 0 1 1 1 1 HSF-type DNA-binding DUF812 PF05667.11 OQR91343.1 - 0.0049 15.8 3.4 0.0054 15.7 3.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF812) CAP_N PF01213.19 OQR91343.1 - 0.0051 16.3 2.7 0.0073 15.8 2.7 1.2 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) N terminal Syntaxin-6_N PF09177.11 OQR91343.1 - 0.0059 17.1 2.3 0.011 16.2 2.3 1.5 1 1 0 1 1 1 1 Syntaxin 6, N-terminal DASH_Hsk3 PF08227.11 OQR91343.1 - 0.0066 16.8 2.7 0.014 15.7 2.7 1.6 1 0 0 1 1 1 1 DASH complex subunit Hsk3 like DUF3450 PF11932.8 OQR91343.1 - 0.0076 15.6 3.7 0.01 15.2 3.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3450) Baculo_PEP_C PF04513.12 OQR91343.1 - 0.011 15.7 1.3 0.018 15.1 1.3 1.3 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus ATG16 PF08614.11 OQR91343.1 - 0.012 15.8 3.3 0.016 15.4 3.3 1.1 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) LidA_Long_CC PF18641.1 OQR91343.1 - 0.015 15.4 2.3 0.023 14.7 2.3 1.3 1 0 0 1 1 1 0 LidA long coiled-coil domain LPP PF04728.13 OQR91343.1 - 0.02 15.3 2.6 0.052 14.0 2.6 1.7 1 0 0 1 1 1 0 Lipoprotein leucine-zipper YlbD_coat PF14071.6 OQR91343.1 - 0.02 15.1 4.8 0.034 14.4 4.8 1.5 1 0 0 1 1 1 0 Putative coat protein HORMA PF02301.18 OQR91343.1 - 0.029 14.0 2.3 0.037 13.6 2.3 1.3 1 0 0 1 1 1 0 HORMA domain AAA_11 PF13086.6 OQR91343.1 - 0.032 14.0 1.9 0.039 13.7 1.9 1.1 1 0 0 1 1 1 0 AAA domain CENP-F_leu_zip PF10473.9 OQR91343.1 - 0.032 14.2 3.1 0.049 13.7 3.1 1.3 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 BLOC1_2 PF10046.9 OQR91343.1 - 0.036 14.4 0.9 0.065 13.5 0.9 1.5 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 FapA PF03961.13 OQR91343.1 - 0.041 12.5 1.9 0.047 12.3 1.9 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A DUF1664 PF07889.12 OQR91343.1 - 0.043 13.8 2.2 0.067 13.2 2.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Phlebovirus_NSM PF07246.11 OQR91343.1 - 0.089 12.2 0.9 0.12 11.8 0.9 1.2 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M DUF5082 PF16888.5 OQR91343.1 - 0.14 12.5 3.4 0.14 12.5 0.7 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF5082) DUF5304 PF17230.2 OQR91343.1 - 0.15 12.3 0.1 0.22 11.7 0.1 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5304) Spectrin PF00435.21 OQR91343.1 - 0.16 12.5 3.0 0.29 11.6 2.6 1.6 1 1 0 1 1 1 0 Spectrin repeat HIP1_clath_bdg PF16515.5 OQR91343.1 - 0.23 12.1 5.6 0.23 12.1 4.7 1.5 1 1 0 1 1 1 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Jnk-SapK_ap_N PF09744.9 OQR91343.1 - 0.25 11.6 5.8 0.38 11.0 5.8 1.3 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 DUF4407 PF14362.6 OQR91343.1 - 0.43 9.9 1.8 0.54 9.6 1.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) TolA_bind_tri PF16331.5 OQR91343.1 - 0.82 9.8 7.4 0.32 11.1 4.7 1.7 2 0 0 2 2 2 0 TolA binding protein trimerisation HSF_DNA-bind PF00447.17 OQR91344.1 - 8.2e-28 96.9 0.5 1.4e-27 96.1 0.5 1.4 1 0 0 1 1 1 1 HSF-type DNA-binding YlqD PF11068.8 OQR91344.1 - 0.0096 16.3 0.6 0.015 15.7 0.6 1.2 1 0 0 1 1 1 1 YlqD protein FlaC_arch PF05377.11 OQR91344.1 - 0.042 14.2 0.5 0.11 12.9 0.5 1.6 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) DUF4988 PF16378.5 OQR91344.1 - 0.11 12.2 0.7 0.22 11.2 0.5 1.5 1 1 0 1 1 1 0 Domain of unknown function Pkinase PF00069.25 OQR91345.1 - 7.3e-79 264.8 0.0 7.2e-41 140.3 0.0 2.8 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 OQR91345.1 - 7.2e-76 254.9 0.0 2.1e-39 135.4 0.0 3.4 3 0 0 3 3 3 2 Protein tyrosine kinase NAD_binding_1 PF00175.21 OQR91345.1 - 0.00013 22.6 0.0 0.00058 20.5 0.0 2.2 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain LRR_8 PF13855.6 OQR91345.1 - 0.00027 20.6 1.4 0.00087 19.0 1.4 2.0 1 0 0 1 1 1 1 Leucine rich repeat Kdo PF06293.14 OQR91345.1 - 0.00053 19.4 0.1 1.1 8.6 0.0 2.7 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family CCDC32 PF14989.6 OQR91345.1 - 0.00062 19.8 1.5 0.0015 18.5 1.5 1.6 1 0 0 1 1 1 1 Coiled-coil domain containing 32 Kinase-like PF14531.6 OQR91345.1 - 0.013 14.8 0.0 0.079 12.3 0.0 2.0 2 0 0 2 2 2 0 Kinase-like Syndecan PF01034.20 OQR91345.1 - 0.02 14.8 0.0 0.062 13.2 0.0 1.8 1 0 0 1 1 1 0 Syndecan domain DUF2207 PF09972.9 OQR91345.1 - 0.057 12.2 0.4 0.7 8.6 0.1 2.2 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) TMEM154 PF15102.6 OQR91345.1 - 0.06 13.3 0.3 1.9 8.4 0.0 2.6 2 0 0 2 2 2 0 TMEM154 protein family ASFV_J13L PF05568.11 OQR91345.1 - 0.078 12.7 0.1 0.28 10.9 0.1 1.9 1 0 0 1 1 1 0 African swine fever virus J13L protein DUF3278 PF11683.8 OQR91345.1 - 0.14 12.3 0.4 0.43 10.7 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3278) DUF3627 PF12299.8 OQR91345.1 - 1.7 8.7 6.1 0.6 10.2 1.6 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3627) LRR_4 PF12799.7 OQR91345.1 - 2 8.9 10.0 11 6.6 5.9 3.1 1 1 1 2 2 2 0 Leucine Rich repeats (2 copies) Abhydrolase_1 PF00561.20 OQR91346.1 - 2e-23 83.4 0.1 1.4e-16 60.9 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 OQR91346.1 - 2.8e-22 80.4 0.0 3.5e-22 80.1 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 OQR91346.1 - 7.8e-16 58.1 0.0 4.2e-15 55.7 0.0 1.9 1 1 0 1 1 1 1 Serine aminopeptidase, S33 UPF0227 PF05728.12 OQR91346.1 - 0.0002 21.3 0.1 0.02 14.9 0.0 2.5 2 1 0 2 2 2 1 Uncharacterised protein family (UPF0227) Abhydrolase_2 PF02230.16 OQR91346.1 - 0.0004 20.3 0.1 3.3 7.4 0.0 3.4 2 1 0 2 2 2 2 Phospholipase/Carboxylesterase Esterase PF00756.20 OQR91346.1 - 0.0011 18.7 0.0 0.0028 17.3 0.0 1.9 2 0 0 2 2 2 1 Putative esterase Abhydrolase_4 PF08386.10 OQR91346.1 - 0.0064 16.6 0.0 1.4 9.1 0.0 2.3 2 0 0 2 2 2 1 TAP-like protein DUF676 PF05057.14 OQR91346.1 - 0.044 13.3 0.0 0.088 12.3 0.0 1.5 1 0 0 1 1 1 0 Putative serine esterase (DUF676) LIP PF03583.14 OQR91346.1 - 0.045 13.1 0.1 2.8 7.2 0.0 2.1 2 0 0 2 2 2 0 Secretory lipase PGAP1 PF07819.13 OQR91346.1 - 0.099 12.4 0.1 1.4 8.6 0.1 2.3 1 1 0 1 1 1 0 PGAP1-like protein Palm_thioest PF02089.15 OQR91346.1 - 0.12 12.2 0.0 0.16 11.8 0.0 1.3 1 0 0 1 1 1 0 Palmitoyl protein thioesterase Ribosomal_L12 PF00542.19 OQR91347.1 - 5.4e-23 81.1 7.9 1.2e-22 80.0 7.9 1.6 1 0 0 1 1 1 1 Ribosomal protein L7/L12 C-terminal domain Ribosomal_L12_N PF16320.5 OQR91347.1 - 0.00047 19.8 8.9 0.00081 19.0 1.5 2.8 3 0 0 3 3 3 2 Ribosomal protein L7/L12 dimerisation domain AlkA_N PF06029.11 OQR91347.1 - 0.034 14.4 0.1 2.1 8.7 0.0 2.2 1 1 1 2 2 2 0 AlkA N-terminal domain AsnA PF03590.15 OQR91348.1 - 0.076 12.7 0.0 0.12 12.1 0.0 1.2 1 0 0 1 1 1 0 Aspartate-ammonia ligase Pkinase PF00069.25 OQR91349.1 - 1.1e-17 64.4 0.0 4e-17 62.5 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQR91349.1 - 1.1e-12 47.8 0.0 1e-10 41.4 0.0 2.3 1 1 0 1 1 1 1 Protein tyrosine kinase 2-Hacid_dh PF00389.30 OQR91371.1 - 1.4e-21 76.6 0.1 2.3e-19 69.4 0.0 2.1 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 2-Hacid_dh_C PF02826.19 OQR91371.1 - 6.7e-19 67.9 0.0 1.2e-18 67.1 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.18 OQR91371.1 - 0.13 12.1 0.2 0.32 10.9 0.2 1.6 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain CoA_binding_2 PF13380.6 OQR91371.1 - 0.14 12.7 0.0 0.42 11.1 0.0 1.8 2 0 0 2 2 2 0 CoA binding domain 2-Hacid_dh_C PF02826.19 OQR91372.1 - 1.1e-57 194.3 0.0 2.1e-57 193.4 0.0 1.5 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 OQR91372.1 - 1.4e-27 96.0 0.0 1.6e-27 95.8 0.0 1.0 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 OQR91372.1 - 4.4e-06 26.9 0.1 4.2e-05 23.8 0.0 2.1 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase IlvN PF07991.12 OQR91372.1 - 0.0017 17.9 0.1 0.011 15.3 0.0 2.0 2 0 0 2 2 2 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain CoA_binding_2 PF13380.6 OQR91372.1 - 0.0054 17.2 0.0 0.012 16.1 0.0 1.6 1 0 0 1 1 1 1 CoA binding domain AdoHcyase_NAD PF00670.21 OQR91372.1 - 0.011 15.8 0.2 0.026 14.6 0.2 1.6 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 3HCDH_N PF02737.18 OQR91372.1 - 0.11 12.4 0.1 0.23 11.3 0.1 1.6 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF1933 PF09147.10 OQR91372.1 - 0.11 12.1 0.1 0.36 10.4 0.1 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF1933) GFO_IDH_MocA PF01408.22 OQR91372.1 - 0.12 13.2 1.1 0.93 10.3 0.3 2.5 2 1 0 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold F420_oxidored PF03807.17 OQR91372.1 - 0.36 11.4 2.0 4.6 7.9 0.4 3.0 2 2 1 3 3 3 0 NADP oxidoreductase coenzyme F420-dependent TPR_1 PF00515.28 OQR91377.1 - 5.6e-19 67.1 26.3 1.4e-05 24.7 0.0 8.4 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_8 PF13181.6 OQR91377.1 - 2.5e-17 61.6 17.7 1.1e-06 28.3 0.0 8.5 7 1 0 7 7 7 4 Tetratricopeptide repeat TPR_14 PF13428.6 OQR91377.1 - 1.8e-15 56.3 24.6 3.3e-06 27.4 0.1 9.8 8 3 3 11 11 9 5 Tetratricopeptide repeat TPR_2 PF07719.17 OQR91377.1 - 5.9e-14 51.0 32.5 0.00045 20.1 0.0 8.6 9 0 0 9 9 9 5 Tetratricopeptide repeat TPR_16 PF13432.6 OQR91377.1 - 3.3e-13 50.0 18.5 2.3e-07 31.4 1.5 7.0 5 3 2 7 7 6 3 Tetratricopeptide repeat TPR_11 PF13414.6 OQR91377.1 - 1.3e-12 47.1 13.7 1e-08 34.7 1.0 5.5 3 2 2 5 5 5 2 TPR repeat TPR_19 PF14559.6 OQR91377.1 - 1.2e-11 44.9 17.7 0.0022 18.5 0.1 8.3 5 3 6 11 11 11 3 Tetratricopeptide repeat ANAPC8 PF04049.13 OQR91377.1 - 1.6e-11 44.4 2.6 3.3e-09 36.9 0.9 2.9 2 1 1 3 3 3 1 Anaphase promoting complex subunit 8 / Cdc23 ANAPC3 PF12895.7 OQR91377.1 - 5.1e-09 36.2 26.3 0.033 14.4 0.5 5.6 4 1 0 4 4 4 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.6 OQR91377.1 - 1e-07 31.5 18.8 0.17 12.0 0.3 7.8 8 0 0 8 8 7 3 Tetratricopeptide repeat TPR_17 PF13431.6 OQR91377.1 - 2.7e-05 24.3 22.9 0.0028 17.9 0.0 7.0 10 0 0 10 10 7 2 Tetratricopeptide repeat TPR_6 PF13174.6 OQR91377.1 - 0.00067 20.1 32.0 0.38 11.5 0.7 9.6 11 0 0 11 11 10 2 Tetratricopeptide repeat NARP1 PF12569.8 OQR91377.1 - 0.0018 17.3 7.4 0.2 10.6 0.8 3.5 1 1 1 2 2 2 2 NMDA receptor-regulated protein 1 TPR_9 PF13371.6 OQR91377.1 - 0.002 18.3 18.4 0.012 15.8 0.6 6.1 3 1 4 7 7 7 2 Tetratricopeptide repeat TPR_15 PF13429.6 OQR91377.1 - 0.021 14.1 11.6 0.033 13.4 2.1 4.2 2 1 2 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.6 OQR91377.1 - 0.067 13.5 21.4 1.4 9.3 0.2 6.6 5 2 2 7 7 7 0 Tetratricopeptide repeat DUF3808 PF10300.9 OQR91377.1 - 0.099 11.4 4.3 0.19 10.4 0.4 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF3808) DUF2491 PF10679.9 OQR91377.1 - 0.13 11.4 0.4 0.9 8.7 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2491) Sel1 PF08238.12 OQR91377.1 - 0.4 11.4 9.1 90 4.0 0.5 5.7 5 1 0 5 5 4 0 Sel1 repeat WD40 PF00400.32 OQR91379.1 - 1.7e-17 63.4 0.2 5.3e-08 33.4 0.0 2.5 2 0 0 2 2 2 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OQR91379.1 - 0.0069 16.7 0.0 5 7.5 0.0 2.8 1 1 1 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 OQR91379.1 - 0.048 13.5 0.0 0.075 12.9 0.0 1.3 1 0 0 1 1 1 0 Eukaryotic translation initiation factor eIF2A Atg14 PF10186.9 OQR91389.1 - 3.2e-08 33.0 3.2 5.1e-08 32.4 3.2 1.3 1 0 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 Cnn_1N PF07989.11 OQR91389.1 - 3.6 7.8 8.2 0.95 9.7 0.8 2.6 1 1 1 2 2 2 0 Centrosomin N-terminal motif 1 Epimerase PF01370.21 OQR91390.1 - 1.2e-23 83.8 0.1 1.7e-23 83.3 0.1 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 OQR91390.1 - 9.5e-19 67.6 0.1 1.6e-11 43.9 0.1 2.2 1 1 1 2 2 2 2 Male sterility protein 3Beta_HSD PF01073.19 OQR91390.1 - 4.6e-18 65.2 0.1 6.2e-18 64.8 0.1 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 OQR91390.1 - 1.6e-17 64.0 0.0 2.1e-17 63.6 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 OQR91390.1 - 3.1e-13 49.9 0.0 9.3e-13 48.3 0.0 1.9 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 OQR91390.1 - 2.3e-07 30.2 0.1 3.1e-07 29.8 0.1 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 OQR91390.1 - 3.9e-07 29.5 0.1 8.4e-07 28.4 0.1 1.5 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NmrA PF05368.13 OQR91390.1 - 0.0005 19.7 0.1 0.00096 18.8 0.1 1.4 1 0 0 1 1 1 1 NmrA-like family KR PF08659.10 OQR91390.1 - 0.00065 19.7 0.2 0.032 14.2 0.2 2.2 1 1 0 1 1 1 1 KR domain adh_short PF00106.25 OQR91390.1 - 0.011 15.3 0.1 0.065 12.7 0.1 2.2 1 1 0 1 1 1 0 short chain dehydrogenase Pkinase PF00069.25 OQR91392.1 - 1.3e-56 191.9 0.0 6.2e-56 189.7 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQR91392.1 - 6.1e-33 114.2 0.1 5.4e-32 111.1 0.0 1.9 1 1 1 2 2 2 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OQR91392.1 - 0.0067 15.2 0.0 0.01 14.6 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase YrbL-PhoP_reg PF10707.9 OQR91392.1 - 0.0068 16.0 0.1 0.12 11.9 0.0 2.2 2 0 0 2 2 2 1 PhoP regulatory network protein YrbL Kinase-like PF14531.6 OQR91392.1 - 0.025 13.9 0.2 0.099 11.9 0.1 2.1 2 1 0 2 2 2 0 Kinase-like APH PF01636.23 OQR91392.1 - 0.031 14.2 0.1 0.31 10.9 0.1 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.14 OQR91392.1 - 0.055 12.8 0.3 0.094 12.1 0.3 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 OQR91392.1 - 0.16 11.5 0.0 0.43 10.2 0.0 1.7 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 DUF4404 PF14357.6 OQR91393.1 - 0.95 10.1 6.8 2.9 8.6 0.2 4.0 4 0 0 4 4 4 0 Domain of unknown function (DUF4404) NinG PF05766.12 OQR91393.1 - 2 8.3 6.4 4.1 7.3 6.4 1.5 1 0 0 1 1 1 0 Bacteriophage Lambda NinG protein FANCI_S2 PF14676.6 OQR91393.1 - 7 6.9 10.5 1.5 9.1 2.5 3.9 2 1 1 3 3 3 0 FANCI solenoid 2 AA_permease_2 PF13520.6 OQR91399.1 - 7.6e-50 170.0 46.0 1.1e-49 169.4 46.0 1.2 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 OQR91399.1 - 3.5e-05 22.6 45.4 5.5e-05 21.9 45.4 1.2 1 0 0 1 1 1 1 Amino acid permease DUF5337 PF17272.2 OQR91399.1 - 7.1 6.5 6.9 10 6.0 1.2 3.3 3 0 0 3 3 3 0 Family of unknown function (DUF5337) DUF4199 PF13858.6 OQR91400.1 - 0.28 11.6 4.1 0.15 12.4 0.5 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF4199) Notch PF00066.17 OQR91402.1 - 0.0054 17.2 6.8 0.013 15.9 6.8 1.7 1 1 0 1 1 1 1 LNR domain zf-RING_2 PF13639.6 OQR91403.1 - 9.3e-09 35.5 10.0 1.4e-08 34.9 10.0 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 OQR91403.1 - 7.6e-08 32.1 9.1 1.1e-07 31.5 9.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 OQR91403.1 - 1.2e-07 31.4 10.2 1.9e-07 30.8 10.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 OQR91403.1 - 3.4e-07 30.0 8.0 4.9e-07 29.5 8.0 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 OQR91403.1 - 1.9e-05 24.7 8.8 3.9e-05 23.7 8.8 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.7 OQR91403.1 - 2.5e-05 24.5 10.6 0.00024 21.3 10.6 2.1 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 OQR91403.1 - 3e-05 24.0 3.0 3.1e-05 23.9 1.6 1.8 1 1 1 2 2 2 1 RING-type zinc-finger Prok-RING_4 PF14447.6 OQR91403.1 - 0.00018 21.3 9.1 0.0003 20.6 9.1 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 OQR91403.1 - 0.003 17.5 8.7 0.006 16.5 8.7 1.5 1 0 0 1 1 1 1 zinc-RING finger domain Zn-C2H2_12 PF18112.1 OQR91403.1 - 0.0092 16.4 0.1 0.033 14.7 0.1 2.0 1 0 0 1 1 1 1 Autophagy receptor zinc finger-C2H2 domain zf-RING_10 PF16685.5 OQR91403.1 - 0.0095 16.1 5.4 0.017 15.3 5.4 1.3 1 0 0 1 1 1 1 zinc RING finger of MSL2 SPT6_acidic PF14632.6 OQR91403.1 - 0.042 14.4 0.1 0.057 14.0 0.1 1.2 1 0 0 1 1 1 0 Acidic N-terminal SPT6 zf-ANAPC11 PF12861.7 OQR91403.1 - 0.061 13.4 4.3 0.13 12.3 4.3 1.6 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_6 PF14835.6 OQR91403.1 - 0.069 13.0 4.0 0.12 12.3 4.0 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-P11 PF03854.14 OQR91403.1 - 0.079 12.6 6.4 0.14 11.8 6.4 1.4 1 0 0 1 1 1 0 P-11 zinc finger Baculo_IE-1 PF05290.11 OQR91403.1 - 0.084 12.8 4.8 0.13 12.2 4.8 1.3 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) zf-RING_4 PF14570.6 OQR91403.1 - 0.097 12.5 5.6 0.49 10.2 6.0 2.0 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_11 PF17123.5 OQR91403.1 - 0.51 10.1 9.3 1.2 8.9 9.3 1.7 1 0 0 1 1 1 0 RING-like zinc finger DZR PF12773.7 OQR91403.1 - 0.57 10.2 4.3 1.1 9.4 4.3 1.5 1 0 0 1 1 1 0 Double zinc ribbon IBR PF01485.21 OQR91403.1 - 2.7 8.3 9.7 8.6 6.7 7.8 2.6 1 1 1 2 2 2 0 IBR domain, a half RING-finger domain Ras PF00071.22 OQR91404.1 - 2.1e-62 209.5 0.2 2.9e-62 209.0 0.2 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OQR91404.1 - 7.8e-36 122.9 0.1 1.3e-35 122.2 0.1 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OQR91404.1 - 1.2e-14 54.2 0.1 1.8e-14 53.6 0.1 1.3 1 1 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 OQR91404.1 - 6.5e-07 29.4 0.0 1e-06 28.8 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 OQR91404.1 - 3.1e-05 24.0 0.2 0.019 14.9 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 OQR91404.1 - 5.2e-05 22.9 0.2 0.00023 20.8 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 OQR91404.1 - 0.0013 18.1 0.0 0.0023 17.4 0.0 1.5 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_16 PF13191.6 OQR91404.1 - 0.0024 18.3 0.2 0.0048 17.3 0.2 1.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 OQR91404.1 - 0.0057 16.9 0.1 0.028 14.7 0.1 2.0 1 1 0 1 1 1 1 AAA domain PduV-EutP PF10662.9 OQR91404.1 - 0.01 15.6 0.0 0.017 14.8 0.0 1.7 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation ABC_tran PF00005.27 OQR91404.1 - 0.01 16.3 0.0 0.02 15.4 0.0 1.6 1 1 0 1 1 1 0 ABC transporter SRPRB PF09439.10 OQR91404.1 - 0.026 14.0 0.0 0.049 13.1 0.0 1.5 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_14 PF13173.6 OQR91404.1 - 0.034 14.2 0.0 0.097 12.7 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_24 PF13479.6 OQR91404.1 - 0.036 13.8 0.1 0.068 12.9 0.1 1.7 1 1 0 1 1 1 0 AAA domain KAP_NTPase PF07693.14 OQR91404.1 - 0.042 13.1 0.0 0.057 12.7 0.0 1.2 1 0 0 1 1 1 0 KAP family P-loop domain Herpes_glycop_H PF02489.16 OQR91404.1 - 0.056 12.0 0.0 0.058 11.9 0.0 1.1 1 0 0 1 1 1 0 Herpesvirus glycoprotein H main domain FeoB_N PF02421.18 OQR91404.1 - 0.064 12.8 0.1 0.26 10.8 0.0 1.8 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_5 PF07728.14 OQR91404.1 - 0.073 13.1 0.0 0.35 10.9 0.0 2.0 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) TniB PF05621.11 OQR91404.1 - 0.098 12.1 0.0 0.22 10.9 0.0 1.6 1 0 0 1 1 1 0 Bacterial TniB protein YtzH PF14165.6 OQR91404.1 - 0.16 12.4 0.0 0.52 10.7 0.0 1.8 2 0 0 2 2 2 0 YtzH-like protein AAA_21 PF13304.6 OQR91404.1 - 0.25 11.1 0.5 0.4 10.4 0.5 1.4 1 1 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system LRR_8 PF13855.6 OQR91406.1 - 1.9e-08 33.9 7.4 1.3e-06 28.1 0.7 4.3 4 1 1 5 5 5 2 Leucine rich repeat WD40 PF00400.32 OQR91406.1 - 1.4e-05 25.8 4.8 0.0025 18.6 1.1 4.9 4 0 0 4 4 4 1 WD domain, G-beta repeat LRR_4 PF12799.7 OQR91406.1 - 0.0013 19.1 9.6 0.0051 17.2 0.8 4.7 4 1 2 6 6 6 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 OQR91406.1 - 0.021 15.3 0.3 2 9.3 0.1 4.3 3 0 0 3 3 3 0 Leucine Rich Repeat Peptidase_M24 PF00557.24 OQR91425.1 - 8.8e-26 90.9 0.3 1.6e-25 90.1 0.3 1.4 1 0 0 1 1 1 1 Metallopeptidase family M24 Rhodanese PF00581.20 OQR91425.1 - 7.5e-21 74.7 0.0 2.7e-10 40.7 0.0 2.9 2 1 0 2 2 2 2 Rhodanese-like domain Zn_Tnp_IS91 PF14319.6 OQR91425.1 - 1.5 8.9 5.3 4.3 7.4 0.5 2.7 2 0 0 2 2 2 0 Transposase zinc-binding domain Utp21 PF04192.12 OQR91426.1 - 2.2e-53 181.2 0.2 3.8e-53 180.4 0.2 1.3 1 0 0 1 1 1 1 Utp21 specific WD40 associated putative domain WD40 PF00400.32 OQR91426.1 - 2.4e-28 97.8 26.3 1e-10 42.0 2.0 11.3 12 0 0 12 12 11 6 WD domain, G-beta repeat HAD_2 PF13419.6 OQR91426.1 - 2.5e-22 79.8 0.0 4.6e-22 79.0 0.0 1.5 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase ANAPC4_WD40 PF12894.7 OQR91426.1 - 1.2e-14 54.3 0.0 0.00063 20.0 0.0 5.7 4 2 2 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 OQR91426.1 - 1.2e-09 37.4 7.4 0.019 13.6 0.4 5.0 2 2 3 5 5 5 4 Nucleoporin Nup120/160 Hydrolase PF00702.26 OQR91426.1 - 2.2e-08 34.6 0.0 1.5e-07 31.9 0.0 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase WD40_like PF17005.5 OQR91426.1 - 3e-06 26.8 0.0 0.1 11.9 0.0 4.1 4 1 0 4 4 4 1 WD40-like domain Ge1_WD40 PF16529.5 OQR91426.1 - 0.001 18.1 0.6 3.9 6.3 0.1 3.6 2 2 1 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Cytochrom_D1 PF02239.16 OQR91426.1 - 0.0084 14.7 0.0 0.022 13.3 0.0 1.6 1 0 0 1 1 1 1 Cytochrome D1 heme domain Hydrolase_6 PF13344.6 OQR91426.1 - 0.012 15.7 0.0 1.2 9.3 0.0 2.8 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase Hira PF07569.11 OQR91426.1 - 0.015 15.0 1.6 19 4.9 0.0 4.9 6 0 0 6 6 6 0 TUP1-like enhancer of split Hydrolase_like PF13242.6 OQR91426.1 - 0.088 12.9 0.0 0.2 11.8 0.0 1.6 1 0 0 1 1 1 0 HAD-hyrolase-like Glu_synthase PF01645.17 OQR91436.1 - 4.5e-152 506.4 0.7 2.5e-150 500.7 0.2 2.2 2 0 0 2 2 2 2 Conserved region in glutamate synthase GATase_2 PF00310.21 OQR91436.1 - 4.3e-125 417.7 0.0 5.9e-125 417.3 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Glu_syn_central PF04898.14 OQR91436.1 - 2.3e-110 368.5 0.0 4.8e-110 367.4 0.0 1.5 1 0 0 1 1 1 1 Glutamate synthase central domain GXGXG PF01493.19 OQR91436.1 - 1e-74 250.3 6.5 1.9e-74 249.4 6.5 1.5 1 0 0 1 1 1 1 GXGXG motif FMN_dh PF01070.18 OQR91436.1 - 0.11 11.4 0.8 0.3 10.1 0.5 1.8 2 0 0 2 2 2 0 FMN-dependent dehydrogenase Peptidase_S74 PF13884.6 OQR91443.1 - 8.2e-12 45.3 0.3 1.3e-11 44.6 0.3 1.3 1 0 0 1 1 1 1 Chaperone of endosialidase Phage_BR0599 PF09356.10 OQR91443.1 - 0.022 15.1 1.3 38 4.7 0.0 6.9 3 0 0 3 3 3 0 Phage conserved hypothetical protein BR0599 Ribosomal_L27e PF01777.18 OQR91445.1 - 1.1e-30 105.9 6.7 1.5e-30 105.4 6.7 1.2 1 0 0 1 1 1 1 Ribosomal L27e protein family KOW PF00467.29 OQR91445.1 - 3.1e-05 23.8 2.0 3.1e-05 23.8 2.0 2.1 3 0 0 3 3 3 1 KOW motif DUF1322 PF07032.11 OQR91445.1 - 0.069 13.7 0.1 0.16 12.5 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1322) zf-C2H2_jaz PF12171.8 OQR91446.1 - 2.2e-07 31.0 4.8 3.5e-05 24.0 0.7 2.3 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.6 OQR91446.1 - 2.2e-05 24.9 3.4 0.045 14.6 0.2 2.3 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.26 OQR91446.1 - 7.8e-05 22.9 2.4 0.14 12.7 0.1 2.3 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-Di19 PF05605.12 OQR91446.1 - 0.0026 18.0 2.8 0.078 13.3 0.3 2.2 1 1 1 2 2 2 2 Drought induced 19 protein (Di19), zinc-binding zf-met PF12874.7 OQR91446.1 - 0.01 16.2 2.8 0.84 10.1 0.3 2.3 2 0 0 2 2 2 0 Zinc-finger of C2H2 type LIM PF00412.22 OQR91446.1 - 0.022 15.0 1.0 0.042 14.1 1.0 1.5 1 1 0 1 1 1 0 LIM domain zf-C2H2_2 PF12756.7 OQR91446.1 - 0.098 13.0 3.0 5.9 7.3 0.2 2.2 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) PyrI_C PF02748.15 OQR91446.1 - 0.11 12.5 8.8 2.4 8.2 3.2 2.3 1 1 1 2 2 2 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain DUF629 PF04780.12 OQR91446.1 - 0.19 10.3 0.9 0.25 9.8 0.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF629) Elf1 PF05129.13 OQR91446.1 - 1.2 9.2 5.5 6.7 6.8 1.4 2.3 1 1 1 2 2 2 0 Transcription elongation factor Elf1 like zf-BED PF02892.15 OQR91446.1 - 3.4 7.8 6.7 10 6.2 1.3 2.2 1 1 1 2 2 2 0 BED zinc finger DUF4187 PF13821.6 OQR91446.1 - 4.4 7.2 6.2 2.4 8.0 1.5 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4187) PACT_coil_coil PF10495.9 OQR91447.1 - 0.00051 20.6 0.2 0.0014 19.2 0.2 1.8 1 1 0 1 1 1 1 Pericentrin-AKAP-450 domain of centrosomal targeting protein Spc110_C PF18520.1 OQR91447.1 - 0.017 14.7 0.7 0.041 13.5 0.7 1.6 1 0 0 1 1 1 0 Spindle pole body component 110 C-terminal domain Mlo PF03094.15 OQR91447.1 - 0.025 13.0 21.4 0.022 13.1 3.4 2.6 3 0 0 3 3 3 0 Mlo family DUF5381 PF17353.2 OQR91447.1 - 9.4 6.0 10.3 1.4 8.6 4.8 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5381) Pkinase_Tyr PF07714.17 OQR91448.1 - 7.6e-32 110.6 0.0 1e-31 110.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OQR91448.1 - 2.8e-26 92.5 0.0 3.9e-26 92.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain AAA PF00004.29 OQR91458.1 - 8.6e-40 136.2 0.0 4.7e-38 130.6 0.0 2.6 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) DAO PF01266.24 OQR91458.1 - 5.2e-33 115.1 0.0 8.3e-33 114.4 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase AAA_lid_3 PF17862.1 OQR91458.1 - 1.3e-08 34.5 0.1 5.2e-08 32.6 0.1 2.1 1 0 0 1 1 1 1 AAA+ lid domain RuvB_N PF05496.12 OQR91458.1 - 1.4e-05 24.9 0.0 3.8e-05 23.5 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 OQR91458.1 - 0.00033 20.9 0.4 0.068 13.4 0.1 3.8 3 1 0 3 3 3 1 AAA domain AAA_16 PF13191.6 OQR91458.1 - 0.00089 19.7 0.1 0.014 15.8 0.0 2.8 2 1 0 2 2 2 1 AAA ATPase domain AAA_2 PF07724.14 OQR91458.1 - 0.0013 18.9 0.5 0.08 13.0 0.0 3.4 4 0 0 4 4 3 1 AAA domain (Cdc48 subfamily) LisH PF08513.11 OQR91458.1 - 0.0019 18.1 0.1 0.004 17.1 0.1 1.5 1 0 0 1 1 1 1 LisH TIP49 PF06068.13 OQR91458.1 - 0.0024 17.1 0.0 0.0053 16.0 0.0 1.5 2 0 0 2 2 1 1 TIP49 P-loop domain NAD_binding_9 PF13454.6 OQR91458.1 - 0.007 16.4 0.0 0.24 11.4 0.0 2.4 2 0 0 2 2 2 1 FAD-NAD(P)-binding RNA_helicase PF00910.22 OQR91458.1 - 0.0076 16.6 0.1 0.046 14.1 0.0 2.4 2 0 0 2 2 2 1 RNA helicase Mg_chelatase PF01078.21 OQR91458.1 - 0.01 15.2 0.1 0.024 14.0 0.1 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_14 PF13173.6 OQR91458.1 - 0.012 15.7 0.0 0.047 13.7 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 OQR91458.1 - 0.016 14.9 0.2 0.056 13.2 0.0 2.0 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 OQR91458.1 - 0.017 15.1 0.0 0.034 14.2 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_5 PF07728.14 OQR91458.1 - 0.025 14.6 0.9 0.087 12.8 0.0 2.4 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) Amino_oxidase PF01593.24 OQR91458.1 - 0.034 13.4 0.0 0.059 12.6 0.0 1.4 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase Lycopene_cycl PF05834.12 OQR91458.1 - 0.039 13.0 0.0 1.8 7.5 0.0 2.3 2 0 0 2 2 2 0 Lycopene cyclase protein MAJIN PF15077.6 OQR91458.1 - 0.041 13.7 3.3 0.076 12.8 3.3 1.4 1 0 0 1 1 1 0 Membrane-anchored junction protein NACHT PF05729.12 OQR91458.1 - 0.044 13.7 0.0 0.16 11.9 0.0 1.9 1 0 0 1 1 1 0 NACHT domain Pyr_redox_2 PF07992.14 OQR91458.1 - 0.047 12.9 0.3 5.5 6.1 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase IstB_IS21 PF01695.17 OQR91458.1 - 0.05 13.3 0.0 0.15 11.8 0.0 1.8 1 0 0 1 1 1 0 IstB-like ATP binding protein NTPase_1 PF03266.15 OQR91458.1 - 0.059 13.3 0.5 0.36 10.7 0.0 2.4 3 0 0 3 3 3 0 NTPase AAA_25 PF13481.6 OQR91458.1 - 0.098 12.2 0.1 0.81 9.2 0.1 2.5 2 1 1 3 3 3 0 AAA domain AAA_18 PF13238.6 OQR91458.1 - 0.13 12.8 0.0 0.51 10.9 0.0 2.1 1 0 0 1 1 1 0 AAA domain ApbA PF02558.16 OQR91458.1 - 0.15 11.7 0.2 0.41 10.3 0.2 1.7 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA NAD_binding_8 PF13450.6 OQR91458.1 - 0.25 11.6 0.4 0.75 10.1 0.4 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain FG-GAP_2 PF14312.6 OQR91459.1 - 1e-83 275.4 55.2 3.6e-11 43.1 0.1 15.3 15 0 0 15 15 15 14 FG-GAP repeat Calx-beta PF03160.14 OQR91459.1 - 2.8e-09 37.0 0.1 0.0029 17.8 0.1 4.0 3 0 0 3 3 3 3 Calx-beta domain Pribosyltran_N PF13793.6 OQR91460.1 - 1.8e-50 169.7 0.3 1.1e-49 167.2 0.1 2.1 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.6 OQR91460.1 - 4.8e-27 95.2 0.2 1.5e-26 93.6 0.1 1.9 2 0 0 2 2 2 1 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.27 OQR91460.1 - 2.1e-13 50.1 0.7 7e-13 48.4 0.1 2.0 2 0 0 2 2 2 1 Phosphoribosyl transferase domain UPRTase PF14681.6 OQR91460.1 - 0.018 14.5 0.0 0.03 13.7 0.0 1.4 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase DUF1751 PF08551.10 OQR91461.1 - 4.4e-10 40.0 1.8 9.3e-10 39.0 1.8 1.6 1 0 0 1 1 1 1 Eukaryotic integral membrane protein (DUF1751) Rhomboid PF01694.22 OQR91461.1 - 4.8e-08 33.1 4.6 8.8e-08 32.3 4.6 1.5 1 0 0 1 1 1 1 Rhomboid family BatA PF07584.11 OQR91461.1 - 2.1 8.8 6.5 0.74 10.2 0.5 3.0 2 2 1 4 4 4 0 Aerotolerance regulator N-terminal DNA_pol_E_B PF04042.16 OQR91471.1 - 8.5e-43 146.2 0.4 1.2e-42 145.7 0.4 1.2 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B DUF3228 PF11539.8 OQR91471.1 - 0.046 13.2 0.0 0.074 12.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3228) PsiA PF06952.11 OQR91471.1 - 0.06 12.6 0.0 0.11 11.7 0.0 1.4 1 0 0 1 1 1 0 PsiA protein Peptidase_S10 PF00450.22 OQR91472.1 - 8.3e-50 170.4 0.3 9.6e-50 170.2 0.3 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase 2-Hacid_dh_C PF02826.19 OQR91473.1 - 4.2e-35 120.7 0.0 6.8e-35 120.0 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ACT PF01842.25 OQR91473.1 - 6.7e-09 35.4 0.3 2.2e-08 33.7 0.0 2.0 2 0 0 2 2 2 1 ACT domain 2-Hacid_dh PF00389.30 OQR91473.1 - 1.5e-07 31.1 0.0 4.5e-07 29.6 0.0 2.1 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 OQR91473.1 - 0.00016 21.8 0.2 0.00035 20.8 0.2 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase ACT_4 PF13291.6 OQR91473.1 - 0.04 14.5 0.0 0.12 13.0 0.0 1.9 1 0 0 1 1 1 0 ACT domain ACT_6 PF13740.6 OQR91473.1 - 0.04 13.9 0.1 0.25 11.4 0.0 2.4 2 0 0 2 2 2 0 ACT domain DUF3219 PF11514.8 OQR91473.1 - 0.12 12.3 0.0 0.23 11.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3219) UDPG_MGDP_dh_C PF03720.15 OQR91473.1 - 0.17 12.3 0.0 1.7 9.1 0.0 2.3 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain Ank_4 PF13637.6 OQR91476.1 - 2.5e-29 101.3 2.5 1.3e-14 54.4 0.1 3.1 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 OQR91476.1 - 6.2e-21 74.8 0.5 6e-18 65.2 0.2 2.0 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OQR91476.1 - 2.1e-20 72.5 0.7 3.7e-12 46.2 0.2 2.9 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQR91476.1 - 4.1e-16 57.4 1.8 1.2e-05 25.3 0.0 4.1 4 0 0 4 4 4 3 Ankyrin repeat Ank PF00023.30 OQR91476.1 - 2.5e-14 53.0 3.8 7.7e-06 26.1 0.3 3.7 4 0 0 4 4 4 2 Ankyrin repeat Shigella_OspC PF06128.11 OQR91476.1 - 0.065 13.0 0.1 0.79 9.4 0.0 2.0 1 1 1 2 2 2 0 Shigella flexneri OspC protein NMT1_2 PF13379.6 OQR91476.1 - 0.077 12.7 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 NMT1-like family Myotub-related PF06602.14 OQR91477.1 - 5.3e-139 463.0 0.0 1e-138 462.1 0.0 1.4 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain FYVE PF01363.21 OQR91477.1 - 9.5e-19 67.3 9.5 2.3e-18 66.1 9.5 1.7 1 0 0 1 1 1 1 FYVE zinc finger Y_phosphatase PF00102.27 OQR91477.1 - 7.9e-06 25.6 0.1 1.6e-05 24.6 0.1 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase 3-PAP PF12578.8 OQR91477.1 - 0.00014 21.7 0.0 0.00035 20.3 0.0 1.7 1 0 0 1 1 1 1 Myotubularin-associated protein DSPc PF00782.20 OQR91477.1 - 0.00035 20.4 0.3 0.00092 19.0 0.1 1.8 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 OQR91477.1 - 0.0016 18.5 0.0 0.0029 17.6 0.0 1.5 1 0 0 1 1 1 1 Tyrosine phosphatase family GRAM PF02893.20 OQR91477.1 - 0.002 18.0 0.0 0.007 16.2 0.0 1.9 1 0 0 1 1 1 1 GRAM domain PTPlike_phytase PF14566.6 OQR91477.1 - 0.43 10.7 2.5 0.52 10.4 0.0 2.4 3 0 0 3 3 3 0 Inositol hexakisphosphate LRR_8 PF13855.6 OQR91478.1 - 6.4e-09 35.4 1.1 3e-05 23.7 0.4 2.8 1 1 1 2 2 2 2 Leucine rich repeat Notch PF00066.17 OQR91478.1 - 0.0017 18.7 12.7 0.0059 17.0 12.7 1.9 1 0 0 1 1 1 1 LNR domain LRR_4 PF12799.7 OQR91478.1 - 0.038 14.4 8.4 0.21 12.1 0.6 3.6 3 1 0 3 3 3 0 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 OQR91480.1 - 3.9e-26 88.8 21.9 0.0047 16.9 0.1 12.4 13 1 0 13 13 13 8 Leucine Rich repeat LRR_4 PF12799.7 OQR91480.1 - 4.5e-07 30.1 25.0 0.0092 16.4 0.5 6.8 2 1 8 10 10 10 6 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 OQR91480.1 - 6.5e-06 25.8 22.5 0.01 15.6 0.5 6.2 5 2 1 6 6 6 3 Leucine rich repeat LRR_1 PF00560.33 OQR91480.1 - 4.1e-05 23.6 10.0 56 4.9 0.0 7.9 8 1 0 8 8 8 0 Leucine Rich Repeat DUF5392 PF17370.2 OQR91480.1 - 0.13 12.4 0.0 0.25 11.4 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5392) NAD_binding_6 PF08030.12 OQR91482.1 - 2e-35 122.2 0.0 3.9e-35 121.3 0.0 1.5 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 OQR91482.1 - 1e-19 70.6 0.0 2.4e-19 69.4 0.0 1.6 1 0 0 1 1 1 1 FAD-binding domain Pkinase_Tyr PF07714.17 OQR91482.1 - 1.4e-13 50.7 0.0 2.3e-13 50.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OQR91482.1 - 2.1e-13 50.3 0.0 3.9e-13 49.4 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Ferric_reduct PF01794.19 OQR91482.1 - 1e-11 45.0 10.0 2.2e-11 44.0 10.0 1.6 1 0 0 1 1 1 1 Ferric reductase like transmembrane component NAD_binding_1 PF00175.21 OQR91482.1 - 0.0005 20.7 0.0 0.008 16.8 0.0 2.8 2 1 0 2 2 2 1 Oxidoreductase NAD-binding domain EF-hand_7 PF13499.6 OQR91482.1 - 0.00056 20.3 0.3 0.0013 19.1 0.3 1.7 1 0 0 1 1 1 1 EF-hand domain pair FAD_binding_6 PF00970.24 OQR91482.1 - 0.001 19.3 0.0 0.0023 18.2 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain EF-hand_6 PF13405.6 OQR91482.1 - 0.0026 17.5 0.1 0.0085 16.0 0.1 1.9 1 0 0 1 1 1 1 EF-hand domain EF-hand_1 PF00036.32 OQR91482.1 - 0.058 13.0 0.1 0.2 11.3 0.1 1.9 1 0 0 1 1 1 0 EF hand EF-hand_8 PF13833.6 OQR91482.1 - 0.11 12.4 0.0 0.28 11.1 0.0 1.7 1 0 0 1 1 1 0 EF-hand domain pair DUF2025 PF09634.10 OQR91482.1 - 0.12 12.4 0.1 0.3 11.1 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2025) Abhydrolase_1 PF00561.20 OQR91484.1 - 1e-16 61.4 0.1 1.4e-16 60.9 0.1 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 OQR91484.1 - 2e-14 53.5 0.0 2.9e-14 52.9 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 OQR91484.1 - 2.2e-14 54.6 0.6 3.5e-14 53.9 0.6 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.20 OQR91484.1 - 0.00015 21.5 0.0 0.00022 21.0 0.0 1.2 1 0 0 1 1 1 1 Putative esterase PGAP1 PF07819.13 OQR91484.1 - 0.00086 19.1 0.0 0.0027 17.5 0.0 1.7 1 1 1 2 2 2 1 PGAP1-like protein Abhydrolase_5 PF12695.7 OQR91484.1 - 0.0013 18.6 0.0 0.0021 17.8 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Ser_hydrolase PF06821.13 OQR91484.1 - 0.0022 17.9 0.0 0.0034 17.2 0.0 1.4 1 0 0 1 1 1 1 Serine hydrolase DUF915 PF06028.11 OQR91484.1 - 0.0022 17.4 0.0 0.0049 16.2 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF915) Abhydrolase_3 PF07859.13 OQR91484.1 - 0.0036 17.2 0.0 0.0055 16.6 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Ndr PF03096.14 OQR91484.1 - 0.0083 14.9 0.0 0.014 14.2 0.0 1.3 1 0 0 1 1 1 1 Ndr family Palm_thioest PF02089.15 OQR91484.1 - 0.042 13.7 0.0 0.055 13.3 0.0 1.2 1 0 0 1 1 1 0 Palmitoyl protein thioesterase Abhydrolase_2 PF02230.16 OQR91484.1 - 0.13 12.1 0.0 0.3 10.8 0.0 1.6 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase PSP1 PF04468.12 OQR91485.1 - 3.3e-30 104.2 3.2 7.7e-30 103.0 3.2 1.7 1 0 0 1 1 1 1 PSP1 C-terminal conserved region DUF5374 PF17344.2 OQR91486.1 - 0.34 10.8 2.4 3.2 7.7 0.1 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF5374) RUN PF02759.19 OQR91487.1 - 1.1e-15 57.8 0.5 7.3e-15 55.1 0.1 2.5 2 0 0 2 2 2 1 RUN domain RhoGAP PF00620.27 OQR91487.1 - 3.3e-13 49.7 0.4 2e-12 47.2 0.1 2.2 2 0 0 2 2 2 1 RhoGAP domain ELMO_CED12 PF04727.13 OQR91487.1 - 6.7e-08 32.8 0.0 1.6e-07 31.6 0.0 1.6 1 0 0 1 1 1 1 ELMO/CED-12 family SH3_3 PF08239.11 OQR91487.1 - 0.0046 17.2 1.0 0.017 15.4 0.5 2.2 2 0 0 2 2 2 1 Bacterial SH3 domain SH3_4 PF06347.13 OQR91487.1 - 0.04 13.7 0.2 0.13 12.1 0.2 1.8 1 0 0 1 1 1 0 Bacterial SH3 domain GAT PF03127.14 OQR91487.1 - 0.26 11.6 1.5 19 5.7 0.3 3.2 2 0 0 2 2 2 0 GAT domain Alginate_lyase2 PF08787.11 OQR91488.1 - 1.1e-20 74.5 0.0 1.4e-20 74.1 0.0 1.1 1 0 0 1 1 1 1 Alginate lyase DUF1336 PF07059.12 OQR91490.1 - 8.9e-65 218.9 0.0 1.8e-64 217.9 0.0 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF1336) START PF01852.19 OQR91490.1 - 1.3e-13 50.9 0.6 2.1e-13 50.1 0.6 1.2 1 0 0 1 1 1 1 START domain PH PF00169.29 OQR91490.1 - 2.9e-10 40.6 0.0 7.5e-10 39.3 0.0 1.8 1 0 0 1 1 1 1 PH domain PH_8 PF15409.6 OQR91490.1 - 0.0017 18.6 0.0 0.0097 16.2 0.0 2.3 2 0 0 2 2 2 1 Pleckstrin homology domain Sec63 PF02889.16 OQR91491.1 - 0.00013 21.3 0.0 0.00015 21.1 0.0 1.1 1 0 0 1 1 1 1 Sec63 Brl domain DUF267 PF03268.14 OQR91492.1 - 0.41 9.5 6.0 0.9 8.3 0.5 2.7 3 0 0 3 3 3 0 Caenorhabditis protein of unknown function, DUF267 DsbB PF02600.16 OQR91492.1 - 3 8.3 11.1 8.1 6.9 6.0 3.4 3 1 0 3 3 3 0 Disulfide bond formation protein DsbB PX PF00787.24 OQR91501.1 - 1.2e-12 47.8 0.0 1.8e-09 37.6 0.0 2.5 2 0 0 2 2 2 2 PX domain adh_short_C2 PF13561.6 OQR91502.1 - 1.1e-37 129.8 1.7 6.8e-31 107.6 0.8 2.1 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OQR91502.1 - 8.9e-33 113.4 1.2 1.2e-32 113.0 1.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OQR91502.1 - 0.0013 18.6 0.5 0.0054 16.7 0.5 2.0 1 1 0 1 1 1 1 KR domain THF_DHG_CYH_C PF02882.19 OQR91502.1 - 0.014 14.8 0.3 0.058 12.7 0.1 2.0 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Epimerase PF01370.21 OQR91502.1 - 0.026 14.0 0.2 0.092 12.2 0.3 2.0 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family ABC2_membrane_3 PF12698.7 OQR91502.1 - 0.041 13.0 0.3 0.06 12.5 0.3 1.3 1 1 0 1 1 1 0 ABC-2 family transporter protein Ion_trans PF00520.31 OQR91503.1 - 2.5e-34 118.6 15.9 1.9e-15 56.7 1.3 3.2 3 0 0 3 3 3 3 Ion transport protein cNMP_binding PF00027.29 OQR91503.1 - 7.5e-13 48.4 0.0 1.6e-12 47.3 0.0 1.5 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Ion_trans_2 PF07885.16 OQR91503.1 - 3e-09 36.7 1.2 9.5e-09 35.1 1.2 1.9 1 0 0 1 1 1 1 Ion channel zf-C3HC4_3 PF13920.6 OQR91506.1 - 1.3e-10 40.9 17.4 3.1e-10 39.8 17.4 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 OQR91506.1 - 5.2e-07 29.4 16.3 1e-06 28.5 16.3 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 RRM_1 PF00076.22 OQR91506.1 - 1e-06 28.5 0.0 2.4e-06 27.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) K-box PF01486.17 OQR91506.1 - 7.7e-05 22.8 13.9 7.7e-05 22.8 13.9 2.9 1 1 0 2 2 2 1 K-box region Gti1_Pac2 PF09729.9 OQR91506.1 - 0.035 14.2 3.1 0.13 12.4 3.0 2.0 1 1 0 1 1 1 0 Gti1/Pac2 family LMBR1 PF04791.16 OQR91506.1 - 0.63 8.9 5.2 0.92 8.3 5.2 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein Myosin_head PF00063.21 OQR91507.1 - 1.3e-168 562.3 0.0 1.4e-119 400.3 0.0 2.2 2 0 0 2 2 2 2 Myosin head (motor domain) AAA_22 PF13401.6 OQR91507.1 - 0.0099 16.2 0.0 0.04 14.2 0.0 2.1 1 0 0 1 1 1 1 AAA domain IQ PF00612.27 OQR91507.1 - 0.012 15.4 1.1 0.012 15.4 1.1 3.9 4 0 0 4 4 4 0 IQ calmodulin-binding motif HALZ PF02183.18 OQR91507.1 - 0.013 15.7 0.3 0.044 14.0 0.3 2.0 1 0 0 1 1 1 0 Homeobox associated leucine zipper T2SSE PF00437.20 OQR91507.1 - 0.019 14.0 0.0 0.048 12.7 0.0 1.6 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_16 PF13191.6 OQR91507.1 - 0.13 12.6 4.4 0.22 11.9 0.0 2.9 3 0 0 3 3 3 0 AAA ATPase domain ABC_tran_Xtn PF12848.7 OQR91507.1 - 1.1 9.3 3.7 0.48 10.5 0.2 2.2 2 0 0 2 2 2 0 ABC transporter SHIPPO-rpt PF07004.12 OQR91508.1 - 3 8.9 10.6 3.2 8.8 0.0 3.9 5 0 0 5 5 5 0 Sperm-tail PG-rich repeat PI3Ka PF00613.20 OQR91509.1 - 7.2e-21 74.4 2.8 2.6e-20 72.6 0.1 2.7 3 0 0 3 3 3 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) cNMP_binding PF00027.29 OQR91509.1 - 5.1e-06 26.5 0.0 1.2e-05 25.3 0.0 1.6 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain PI3K_C2 PF00792.24 OQR91509.1 - 6.4e-06 26.1 0.1 2.3e-05 24.3 0.0 2.0 2 0 0 2 2 2 1 Phosphoinositide 3-kinase C2 GAF PF01590.26 OQR91509.1 - 0.045 14.4 0.0 0.13 12.9 0.0 1.9 1 0 0 1 1 1 0 GAF domain DUF2805 PF10985.8 OQR91509.1 - 0.45 10.9 1.8 0.53 10.7 0.4 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2805) ABC_tran PF00005.27 OQR91517.1 - 7.8e-17 62.1 0.2 1.9e-16 60.8 0.2 1.6 1 1 0 1 1 1 1 ABC transporter ABC_membrane PF00664.23 OQR91517.1 - 7.7e-16 58.6 13.3 1.1e-15 58.1 13.3 1.3 1 0 0 1 1 1 1 ABC transporter transmembrane region AAA_29 PF13555.6 OQR91517.1 - 0.069 12.9 0.2 0.22 11.3 0.0 1.9 2 0 0 2 2 2 0 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 OQR91517.1 - 0.12 12.3 0.1 0.23 11.4 0.1 1.4 1 0 0 1 1 1 0 RsgA GTPase TsaE PF02367.17 OQR91517.1 - 0.12 12.3 0.0 0.25 11.3 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE DnaB_C PF03796.15 OQR91517.1 - 0.13 11.6 0.0 0.21 10.9 0.0 1.2 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain AAA_25 PF13481.6 OQR91517.1 - 0.19 11.3 0.0 0.32 10.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain Myb_DNA-binding PF00249.31 OQR91518.1 - 5.1e-18 65.0 9.9 5.7e-11 42.4 1.2 3.7 4 0 0 4 4 4 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OQR91518.1 - 4.4e-17 62.1 3.2 2.5e-09 37.3 0.3 3.1 1 1 2 3 3 3 3 Myb-like DNA-binding domain Rap1_C PF11626.8 OQR91518.1 - 0.32 11.1 3.1 0.32 11.1 0.6 2.0 2 0 0 2 2 2 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain Myb_DNA-bind_4 PF13837.6 OQR91518.1 - 0.68 10.3 11.2 3.3 8.2 0.4 3.2 2 2 0 3 3 3 0 Myb/SANT-like DNA-binding domain DSPn PF14671.6 OQR91519.1 - 9e-39 133.1 0.1 1.5e-37 129.1 0.0 2.9 3 0 0 3 3 3 1 Dual specificity protein phosphatase, N-terminal half UEV PF05743.13 OQR91519.1 - 1.7e-35 121.5 0.1 3.8e-35 120.4 0.1 1.6 1 0 0 1 1 1 1 UEV domain Vps23_core PF09454.10 OQR91519.1 - 4.5e-22 77.8 3.9 4.7e-22 77.7 0.9 2.6 3 0 0 3 3 3 1 Vps23 core domain DSPc PF00782.20 OQR91519.1 - 1.9e-16 60.1 0.1 3e-14 52.9 0.0 3.1 3 0 0 3 3 3 1 Dual specificity phosphatase, catalytic domain UQ_con PF00179.26 OQR91519.1 - 7.8e-07 28.8 0.3 2.2e-06 27.4 0.3 1.8 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Y_phosphatase PF00102.27 OQR91519.1 - 6.6e-06 25.9 0.0 2.1e-05 24.2 0.0 1.9 2 0 0 2 2 2 1 Protein-tyrosine phosphatase BET PF17035.5 OQR91519.1 - 0.001 19.2 0.8 0.0024 18.0 0.0 1.9 2 0 0 2 2 2 1 Bromodomain extra-terminal - transcription regulation PTPlike_phytase PF14566.6 OQR91519.1 - 0.0012 19.0 1.5 0.027 14.6 0.0 2.6 2 0 0 2 2 2 1 Inositol hexakisphosphate Edc3_linker PF16598.5 OQR91519.1 - 1.8 9.2 4.3 6.1 7.6 4.3 1.8 1 0 0 1 1 1 0 Linker region of enhancer of mRNA-decapping protein 3 DUF745 PF05335.13 OQR91519.1 - 7.4 6.2 9.0 17 5.1 9.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF745) Ysc84 PF04366.12 OQR91525.1 - 4.5e-34 116.9 0.1 1e-33 115.8 0.1 1.6 1 0 0 1 1 1 1 Las17-binding protein actin regulator FYVE PF01363.21 OQR91525.1 - 7.8e-14 51.6 3.5 7.8e-14 51.6 3.5 3.3 3 1 0 3 3 3 1 FYVE zinc finger zf-ribbon_3 PF13248.6 OQR91525.1 - 0.00029 20.1 1.0 0.00029 20.1 1.0 3.7 4 1 0 4 4 4 1 zinc-ribbon domain zinc_ribbon_2 PF13240.6 OQR91525.1 - 0.00033 20.3 5.5 0.00033 20.3 5.5 3.6 4 0 0 4 4 4 1 zinc-ribbon domain DZR PF12773.7 OQR91525.1 - 0.0024 17.8 1.2 0.0024 17.8 1.2 4.3 3 1 1 4 4 4 1 Double zinc ribbon Prok-RING_2 PF14445.6 OQR91525.1 - 0.006 16.7 3.8 0.006 16.7 3.8 2.1 2 0 0 2 2 2 1 Prokaryotic RING finger family 2 FYVE_2 PF02318.16 OQR91525.1 - 0.049 13.9 0.9 0.049 13.9 0.9 2.7 4 0 0 4 4 4 0 FYVE-type zinc finger BRE PF06113.12 OQR91525.1 - 0.23 10.3 0.0 0.35 9.7 0.0 1.2 1 0 0 1 1 1 0 Brain and reproductive organ-expressed protein (BRE) Lipase_GDSL_2 PF13472.6 OQR91526.1 - 8.2e-10 39.4 0.0 9.3e-10 39.2 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 OQR91526.1 - 0.0029 17.6 0.0 0.0044 17.0 0.0 1.3 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Pkinase_Tyr PF07714.17 OQR91527.1 - 6.7e-38 130.4 0.0 2.2e-37 128.8 0.0 1.9 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OQR91527.1 - 4.8e-37 127.7 0.0 1.9e-36 125.8 0.0 1.9 2 0 0 2 2 2 1 Protein kinase domain Kinase-like PF14531.6 OQR91527.1 - 0.0067 15.8 0.0 0.015 14.7 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 OQR91527.1 - 0.0083 15.0 0.0 0.017 13.9 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Arm PF00514.23 OQR91527.1 - 0.0096 15.9 7.9 7.7 6.7 0.0 7.1 7 0 0 7 7 7 1 Armadillo/beta-catenin-like repeat PUF PF00806.19 OQR91527.1 - 0.07 12.9 0.1 0.34 10.7 0.1 2.3 1 0 0 1 1 1 0 Pumilio-family RNA binding repeat DUF3385 PF11865.8 OQR91527.1 - 0.1 12.5 4.9 0.24 11.3 1.1 3.4 2 1 0 2 2 2 0 Domain of unknown function (DUF3385) Lipase_GDSL_2 PF13472.6 OQR91528.1 - 6.7e-23 82.0 0.0 1.1e-22 81.4 0.0 1.3 2 0 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 OQR91528.1 - 2.2e-14 53.9 0.0 3e-14 53.5 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase ALGX PF16822.5 OQR91528.1 - 0.011 15.5 0.0 0.27 10.9 0.0 2.1 2 0 0 2 2 2 0 SGNH hydrolase-like domain, acetyltransferase AlgX DltD PF04914.12 OQR91528.1 - 0.012 15.0 0.0 0.016 14.6 0.0 1.2 1 0 0 1 1 1 0 DltD protein Lipase_GDSL PF00657.22 OQR91529.1 - 7.6e-06 26.0 0.0 9.2e-06 25.8 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.6 OQR91529.1 - 6e-05 23.5 0.0 7.6e-05 23.2 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Pilin_N PF07790.11 OQR91538.1 - 0.0031 18.4 2.3 0.016 16.1 0.2 2.8 2 1 0 2 2 2 1 Archaeal Type IV pilin, N-terminal SpoIIIAH PF12685.7 OQR91538.1 - 0.018 14.9 0.1 0.026 14.4 0.1 1.2 1 0 0 1 1 1 0 SpoIIIAH-like protein DUF4834 PF16118.5 OQR91538.1 - 0.077 14.0 0.0 2.1 9.3 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) Hamartin PF04388.12 OQR91538.1 - 0.86 8.2 9.1 1.3 7.6 9.1 1.2 1 0 0 1 1 1 0 Hamartin protein Peptidase_M17 PF00883.21 OQR91539.1 - 2e-62 211.3 0.0 2.4e-62 211.0 0.0 1.0 1 0 0 1 1 1 1 Cytosol aminopeptidase family, catalytic domain GCK PF07802.11 OQR91540.1 - 6.4e-20 71.4 1.2 1.3e-19 70.3 1.2 1.5 1 0 0 1 1 1 1 GCK domain tRNA_lig_CPD PF08302.11 OQR91540.1 - 0.054 12.9 0.0 0.081 12.4 0.0 1.3 1 0 0 1 1 1 0 Fungal tRNA ligase phosphodiesterase domain Ank_2 PF12796.7 OQR91543.1 - 3.3e-54 181.4 22.8 4e-16 59.4 1.6 5.6 2 1 4 6 6 6 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQR91543.1 - 6e-47 157.4 7.6 1.6e-10 41.3 0.0 9.2 4 3 5 9 9 9 8 Ankyrin repeats (many copies) Pkinase PF00069.25 OQR91543.1 - 2.3e-46 158.3 0.2 6.8e-46 156.8 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQR91543.1 - 2e-45 155.1 0.0 5e-45 153.8 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase Ank PF00023.30 OQR91543.1 - 9.6e-37 123.8 3.2 3.8e-06 27.1 0.1 8.6 8 1 0 8 8 8 7 Ankyrin repeat Ank_5 PF13857.6 OQR91543.1 - 1.1e-36 124.4 6.0 2.2e-08 34.2 0.0 6.6 3 1 4 7 7 7 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQR91543.1 - 3e-32 107.0 7.7 0.00078 19.7 0.0 9.9 11 0 0 11 11 11 7 Ankyrin repeat Haspin_kinase PF12330.8 OQR91543.1 - 0.023 13.7 0.0 0.049 12.6 0.0 1.6 1 1 0 1 1 1 0 Haspin like kinase domain Kdo PF06293.14 OQR91543.1 - 0.034 13.5 0.1 0.061 12.7 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family COX6B PF02297.17 OQR91544.1 - 2.8e-14 53.1 4.6 3.2e-14 52.9 4.6 1.1 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb RabGAP-TBC PF00566.18 OQR91545.1 - 1.4e-41 142.6 0.2 3.7e-41 141.2 0.2 1.7 1 0 0 1 1 1 1 Rab-GTPase-TBC domain FYVE PF01363.21 OQR91545.1 - 6.9e-16 58.2 13.7 1.6e-15 57.0 13.7 1.7 1 0 0 1 1 1 1 FYVE zinc finger ACBP PF00887.19 OQR91545.1 - 0.0054 16.9 0.0 0.011 15.9 0.0 1.5 1 0 0 1 1 1 1 Acyl CoA binding protein FYVE_2 PF02318.16 OQR91545.1 - 3.2 8.0 11.5 12 6.1 11.0 2.2 1 1 0 1 1 1 0 FYVE-type zinc finger PA26 PF04636.13 OQR91546.1 - 2.6e-06 26.7 0.0 3.4e-06 26.3 0.0 1.1 1 0 0 1 1 1 1 PA26 p53-induced protein (sestrin) HAV_VP PF12944.7 OQR91546.1 - 0.085 12.8 0.0 0.12 12.3 0.0 1.2 1 0 0 1 1 1 0 Hepatitis A virus viral protein VP YjbR PF04237.13 OQR91546.1 - 0.1 13.1 0.0 0.33 11.5 0.0 1.9 2 0 0 2 2 2 0 YjbR Urocanase PF01175.18 OQR91547.1 - 4.7e-87 291.0 0.1 9.7e-87 290.0 0.1 1.6 1 0 0 1 1 1 1 Urocanase Rossmann-like domain Urocanase_C PF17392.2 OQR91547.1 - 1.7e-85 285.4 1.5 1.7e-85 285.4 1.5 1.6 2 0 0 2 2 2 1 Urocanase C-terminal domain Urocanase_N PF17391.2 OQR91547.1 - 5.1e-55 184.6 3.2 7.3e-55 184.1 0.3 2.5 3 0 0 3 3 3 1 Urocanase N-terminal domain Methyltransf_11 PF08241.12 OQR91548.1 - 2.3e-13 50.6 0.0 3.8e-13 49.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OQR91548.1 - 1.1e-10 42.0 0.0 2.2e-10 41.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OQR91548.1 - 2.2e-08 34.7 0.0 3.5e-08 34.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OQR91548.1 - 3.2e-07 30.2 0.0 4.1e-07 29.9 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OQR91548.1 - 0.024 14.5 0.0 0.032 14.1 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_9 PF08003.11 OQR91548.1 - 0.061 12.2 0.0 0.07 12.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) Methyltransf_29 PF03141.16 OQR91548.1 - 0.22 10.0 0.1 0.42 9.1 0.1 1.4 1 1 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase OPT PF03169.15 OQR91549.1 - 2.3e-99 333.7 46.4 2.9e-99 333.4 46.4 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein SEP PF08059.13 OQR91550.1 - 4.3e-27 94.5 0.1 8.1e-27 93.6 0.1 1.5 1 0 0 1 1 1 1 SEP domain UBX PF00789.20 OQR91550.1 - 2.7e-11 43.5 0.0 4.5e-11 42.8 0.0 1.3 1 0 0 1 1 1 1 UBX domain DGF-1_C PF11040.8 OQR91550.1 - 0.11 12.5 0.0 0.32 11.0 0.0 1.8 1 0 0 1 1 1 0 Dispersed gene family protein 1 of Trypanosoma cruzi C-terminus SCO1-SenC PF02630.14 OQR91557.1 - 0.069 13.1 0.2 0.14 12.0 0.1 1.5 1 1 0 1 1 1 0 SCO1/SenC DUF1176 PF06674.11 OQR91557.1 - 0.11 11.9 0.9 0.22 10.9 0.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1176) Ank_2 PF12796.7 OQR91559.1 - 9.1e-19 67.8 10.1 7.6e-08 32.8 0.4 5.3 2 1 4 6 6 6 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQR91559.1 - 2.1e-14 53.7 3.3 6.8e-06 26.5 0.0 7.3 6 3 1 7 7 7 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 OQR91559.1 - 1.3e-13 50.9 3.9 0.0019 18.5 0.0 8.4 3 2 7 10 10 10 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQR91559.1 - 4.6e-07 29.6 2.5 97 4.1 0.0 9.5 11 0 0 11 11 11 0 Ankyrin repeat DUF3447 PF11929.8 OQR91559.1 - 0.013 15.5 3.5 0.28 11.2 0.2 3.9 1 1 2 4 4 4 0 Domain of unknown function (DUF3447) DUF1843 PF08898.10 OQR91559.1 - 0.037 14.5 0.0 3 8.4 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1843) Ank PF00023.30 OQR91559.1 - 0.14 12.7 0.7 1.5e+02 3.1 0.0 5.0 6 1 0 6 6 6 0 Ankyrin repeat Pkinase_Tyr PF07714.17 OQR91560.1 - 2.2e-16 59.9 0.0 3e-16 59.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OQR91560.1 - 8.6e-14 51.5 0.0 1.1e-13 51.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQR91561.1 - 5.3e-25 88.2 0.0 5.9e-25 88.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OQR91561.1 - 1.3e-24 87.1 0.0 1.6e-24 86.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain MatE PF01554.18 OQR91593.1 - 6.5e-50 168.9 35.0 9.9e-26 90.3 16.2 2.5 2 1 0 2 2 2 2 MatE Sulfotransfer_3 PF13469.6 OQR91594.1 - 0.00082 19.8 0.0 0.0012 19.3 0.0 1.3 1 0 0 1 1 1 1 Sulfotransferase family Sulfotransfer_1 PF00685.27 OQR91594.1 - 0.052 13.0 0.0 0.061 12.8 0.0 1.2 1 0 0 1 1 1 0 Sulfotransferase domain Pkinase_Tyr PF07714.17 OQR91595.1 - 5.6e-34 117.6 0.0 7e-34 117.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OQR91595.1 - 1.6e-32 113.0 0.0 2e-32 112.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain DUF4218 PF13960.6 OQR91596.1 - 0.033 13.8 0.1 0.099 12.3 0.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4218) Pkinase_Tyr PF07714.17 OQR91597.1 - 1.7e-60 204.5 0.0 2.7e-56 190.7 0.0 3.8 3 1 0 3 3 3 2 Protein tyrosine kinase Pkinase PF00069.25 OQR91597.1 - 2.4e-53 181.2 0.0 1e-41 143.1 0.0 3.7 2 1 1 3 3 3 3 Protein kinase domain Kdo PF06293.14 OQR91597.1 - 0.022 14.1 1.3 4.3 6.6 0.1 2.5 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OQR91597.1 - 0.22 11.4 1.2 12 5.7 0.3 3.0 2 1 1 3 3 3 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 OQR91597.1 - 1.5 7.7 10.1 0.19 10.6 0.1 3.4 4 0 0 4 4 4 0 Haspin like kinase domain Sulfotransfer_3 PF13469.6 OQR91598.1 - 0.0061 17.0 0.0 0.0063 16.9 0.0 1.2 1 0 0 1 1 1 1 Sulfotransferase family Ax_dynein_light PF10211.9 OQR91614.1 - 1.3e-83 279.6 12.3 2.5e-83 278.6 12.3 1.5 1 0 0 1 1 1 1 Axonemal dynein light chain DUF1744 PF08490.12 OQR91614.1 - 1.9e-79 267.1 0.3 8.7e-78 261.6 0.3 2.3 1 1 0 1 1 1 1 Domain of unknown function (DUF1744) Fer4_10 PF13237.6 OQR91614.1 - 0.1 12.7 1.4 0.49 10.6 1.4 2.2 1 0 0 1 1 1 0 4Fe-4S dicluster domain DpnI_C PF17726.1 OQR91615.1 - 2.4 8.3 7.2 0.69 10.1 0.7 2.4 2 1 1 3 3 3 0 Dam-replacing HTH domain FBPase PF00316.20 OQR91616.1 - 2.3e-51 174.0 0.0 3.1e-51 173.5 0.0 1.1 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase, N-terminal domain DUF1484 PF07363.11 OQR91616.1 - 0.15 13.1 0.2 0.28 12.2 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1484) Meiosis_expr PF15163.6 OQR91617.1 - 2.6e-28 98.5 6.6 3.8e-28 97.9 6.6 1.2 1 0 0 1 1 1 1 Meiosis-expressed TPR_1 PF00515.28 OQR91618.1 - 1.6e-10 40.3 9.7 4.3e-05 23.1 0.0 4.5 3 2 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 OQR91618.1 - 7.6e-07 28.8 13.0 2.1e-05 24.3 0.0 4.3 5 1 0 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.6 OQR91618.1 - 7.7e-06 26.3 1.6 0.00016 22.2 0.2 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.6 OQR91618.1 - 0.00042 20.4 1.8 0.0027 17.8 0.9 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 OQR91618.1 - 0.00091 19.3 0.0 0.00091 19.3 0.0 4.4 5 1 0 5 5 5 1 Tetratricopeptide repeat TPR_19 PF14559.6 OQR91618.1 - 0.001 19.5 5.9 0.0011 19.5 0.9 3.3 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 OQR91618.1 - 0.0011 19.2 1.7 0.031 14.5 0.3 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat ANAPC3 PF12895.7 OQR91618.1 - 0.0016 18.6 0.2 0.0016 18.6 0.2 2.4 2 1 1 3 3 2 1 Anaphase-promoting complex, cyclosome, subunit 3 DUF4366 PF14283.6 OQR91618.1 - 0.003 17.6 0.2 0.0048 16.9 0.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4366) TPR_11 PF13414.6 OQR91618.1 - 0.0032 17.1 0.9 0.4 10.4 0.1 3.4 3 1 1 4 4 4 2 TPR repeat TPR_17 PF13431.6 OQR91618.1 - 0.0047 17.2 1.9 0.089 13.2 0.2 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.6 OQR91618.1 - 0.0078 16.8 2.2 0.33 11.7 0.1 3.6 4 0 0 4 4 3 1 Tetratricopeptide repeat DUF3834 PF12916.7 OQR91618.1 - 0.047 12.9 0.0 0.068 12.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3834) TPR_16 PF13432.6 OQR91618.1 - 0.059 14.0 5.4 0.57 10.9 0.1 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.6 OQR91618.1 - 0.35 11.0 8.9 2.8 8.2 0.2 4.1 3 2 0 3 3 3 0 Tetratricopeptide repeat PGBA_C PF15437.6 OQR91618.1 - 0.35 11.3 7.2 0.81 10.1 2.3 2.4 2 0 0 2 2 2 0 Plasminogen-binding protein pgbA C-terminal Seryl_tRNA_N PF02403.22 OQR91618.1 - 1.6 9.0 6.0 0.55 10.5 3.0 1.7 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Ank_2 PF12796.7 OQR91619.1 - 1.5e-58 195.3 4.5 7.7e-17 61.7 0.1 4.3 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OQR91619.1 - 4.6e-45 151.1 10.1 5.9e-11 42.4 0.0 6.4 2 1 5 7 7 7 6 Ankyrin repeats (many copies) Ank_4 PF13637.6 OQR91619.1 - 1.2e-42 143.7 0.3 1.9e-11 44.2 0.0 4.9 2 2 3 5 5 5 5 Ankyrin repeats (many copies) Ank PF00023.30 OQR91619.1 - 9.6e-38 127.0 4.9 2e-06 28.0 0.0 6.5 7 0 0 7 7 7 6 Ankyrin repeat Ank_3 PF13606.6 OQR91619.1 - 9.8e-35 114.7 0.1 8e-05 22.7 0.0 6.7 7 0 0 7 7 7 6 Ankyrin repeat DUF4988 PF16378.5 OQR91619.1 - 0.0037 16.9 0.2 0.65 9.6 0.0 2.9 1 1 1 3 3 3 1 Domain of unknown function EPSP_synthase PF00275.20 OQR91619.1 - 0.0091 14.7 0.4 0.99 8.0 0.0 2.6 2 1 1 3 3 3 2 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) Imm_superinfect PF14373.6 OQR91619.1 - 0.016 15.1 0.1 12 5.9 0.0 3.7 5 0 0 5 5 5 0 Superinfection immunity protein Pyridoxal_deC PF00282.19 OQR91620.1 - 2.5e-39 135.1 0.0 3.1e-39 134.8 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Beta_elim_lyase PF01212.21 OQR91620.1 - 0.00039 19.8 0.0 0.00049 19.5 0.0 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase SepSecS PF05889.13 OQR91620.1 - 0.0004 19.2 0.0 0.00063 18.5 0.0 1.2 1 0 0 1 1 1 1 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS Aminotran_1_2 PF00155.21 OQR91620.1 - 0.0013 18.0 0.0 0.0021 17.3 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 OQR91620.1 - 0.0056 15.7 0.1 0.034 13.1 0.1 1.9 1 1 0 1 1 1 1 Aminotransferase class-V LacY_symp PF01306.19 OQR91620.1 - 0.13 11.0 0.1 0.2 10.4 0.1 1.2 1 0 0 1 1 1 0 LacY proton/sugar symporter zf-primase PF09329.11 OQR91621.1 - 9.7e-11 41.3 0.8 1.8e-10 40.4 0.8 1.5 1 0 0 1 1 1 1 Primase zinc finger DUF4203 PF13886.6 OQR91622.1 - 1.4e-18 67.3 28.2 1.7e-18 67.0 28.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4203) Ank_2 PF12796.7 OQR91623.1 - 2.6e-34 117.7 1.4 2.7e-12 47.1 0.3 4.1 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQR91623.1 - 8.8e-32 109.1 0.7 8.7e-09 35.7 0.1 5.1 4 1 1 5 5 5 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 OQR91623.1 - 5.9e-26 90.2 0.5 1.6e-07 31.4 0.0 5.4 3 2 2 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQR91623.1 - 2.4e-25 85.8 0.1 7.9e-05 22.8 0.0 6.9 6 1 0 6 6 6 4 Ankyrin repeat Ank PF00023.30 OQR91623.1 - 5.6e-20 70.8 13.6 0.00023 21.5 0.1 7.6 7 2 0 7 7 7 5 Ankyrin repeat HEM4 PF02602.15 OQR91623.1 - 0.024 14.0 0.0 4.1 6.7 0.0 2.2 2 0 0 2 2 2 0 Uroporphyrinogen-III synthase HemD zf-RING_13 PF17977.1 OQR91623.1 - 0.082 13.1 1.2 29 4.9 0.2 3.4 2 1 1 3 3 3 0 RING/Ubox like zinc-binding domain Ras PF00071.22 OQR91624.1 - 7.9e-13 48.3 0.2 3.6e-11 42.9 0.2 2.2 1 1 0 1 1 1 1 Ras family Roc PF08477.13 OQR91624.1 - 3.2e-11 43.5 0.3 1.8e-09 37.8 0.3 2.9 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 OQR91624.1 - 1.2e-06 28.6 0.0 1.6e-06 28.1 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Arf PF00025.21 OQR91624.1 - 4.4e-06 26.3 0.0 0.00023 20.7 0.0 2.5 1 1 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 OQR91624.1 - 0.0023 17.8 0.1 0.032 14.1 0.1 2.2 2 0 0 2 2 2 1 RsgA GTPase ABC_tran PF00005.27 OQR91624.1 - 0.0041 17.6 0.1 0.015 15.8 0.0 1.8 2 0 0 2 2 2 1 ABC transporter RNA_helicase PF00910.22 OQR91624.1 - 0.025 14.9 0.0 0.053 13.9 0.0 1.6 1 0 0 1 1 1 0 RNA helicase ATP-synt_ab PF00006.25 OQR91624.1 - 0.081 12.6 0.2 0.98 9.0 0.0 2.1 1 1 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain SRPRB PF09439.10 OQR91624.1 - 0.092 12.2 0.0 0.24 10.8 0.0 1.8 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_18 PF13238.6 OQR91624.1 - 0.11 13.0 0.2 0.19 12.3 0.2 1.6 1 1 0 1 1 1 0 AAA domain Hpr_kinase_C PF07475.12 OQR91624.1 - 0.16 11.5 0.1 0.24 10.9 0.1 1.3 1 0 0 1 1 1 0 HPr Serine kinase C-terminal domain LYRIC PF15686.5 OQR91625.1 - 0.00057 19.6 0.0 0.0007 19.3 0.0 1.1 1 0 0 1 1 1 1 Lysine-rich CEACAM1 co-isolated protein family Shisa PF13908.6 OQR91625.1 - 0.003 17.8 0.1 0.0059 16.9 0.0 1.5 2 0 0 2 2 1 1 Wnt and FGF inhibitory regulator SIT PF15330.6 OQR91625.1 - 0.0044 17.4 1.4 0.028 14.9 0.6 2.1 2 0 0 2 2 2 1 SHP2-interacting transmembrane adaptor protein, SIT DUF4446 PF14584.6 OQR91625.1 - 0.005 16.8 0.2 0.0073 16.3 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4446) EphA2_TM PF14575.6 OQR91625.1 - 0.0064 17.4 2.9 0.02 15.8 2.9 1.9 1 1 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain WBP-1 PF11669.8 OQR91625.1 - 0.0095 16.6 6.7 0.047 14.3 6.7 2.0 1 1 0 1 1 1 1 WW domain-binding protein 1 FAM163 PF15069.6 OQR91625.1 - 0.0099 16.3 0.0 0.017 15.6 0.0 1.3 1 0 0 1 1 1 1 FAM163 family LegC3_N PF18654.1 OQR91625.1 - 0.011 14.9 3.1 0.015 14.5 3.1 1.1 1 0 0 1 1 1 0 LegC3 N-terminal coiled-coil domain OATP PF03137.20 OQR91625.1 - 0.012 14.0 0.1 0.015 13.6 0.1 1.1 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Mucin PF01456.17 OQR91625.1 - 0.012 15.6 0.1 0.021 14.8 0.1 1.4 1 1 0 1 1 1 0 Mucin-like glycoprotein Rhabdo_glycop PF00974.18 OQR91625.1 - 0.014 13.9 0.3 0.014 13.9 0.3 1.6 2 0 0 2 2 2 0 Rhabdovirus spike glycoprotein NEMP PF10225.9 OQR91625.1 - 0.082 12.6 0.2 0.11 12.1 0.2 1.3 1 0 0 1 1 1 0 NEMP family TMEM52 PF14979.6 OQR91625.1 - 0.097 12.6 1.1 0.24 11.3 0.2 2.0 2 0 0 2 2 2 0 Transmembrane 52 TMEM154 PF15102.6 OQR91625.1 - 0.15 11.9 1.8 0.19 11.6 0.1 2.2 2 1 0 2 2 2 0 TMEM154 protein family RCR PF12273.8 OQR91625.1 - 0.15 12.7 7.4 0.32 11.6 7.4 1.7 1 1 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red Cytadhesin_P30 PF07271.11 OQR91625.1 - 0.21 11.1 2.3 0.39 10.2 2.2 1.4 1 1 0 1 1 1 0 Cytadhesin P30/P32 DUF4834 PF16118.5 OQR91625.1 - 0.23 12.5 0.2 0.23 12.5 0.2 2.0 2 1 1 3 3 3 0 Domain of unknown function (DUF4834) Flot PF15975.5 OQR91625.1 - 0.23 11.7 6.1 0.36 11.0 6.1 1.3 1 0 0 1 1 1 0 Flotillin TMEM51 PF15345.6 OQR91625.1 - 0.28 11.0 9.4 4.5 7.0 9.5 2.1 1 1 0 1 1 1 0 Transmembrane protein 51 Sarcoglycan_2 PF05510.13 OQR91625.1 - 0.3 9.8 3.9 1.8 7.2 3.4 1.9 1 1 1 2 2 2 0 Sarcoglycan alpha/epsilon DUF4381 PF14316.6 OQR91625.1 - 0.37 11.0 10.2 0.1 12.8 4.9 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4381) Ctr PF04145.15 OQR91625.1 - 0.73 10.4 2.1 0.96 10.1 2.1 1.5 1 1 0 1 1 1 0 Ctr copper transporter family TMIE PF16038.5 OQR91625.1 - 0.87 9.5 7.1 2.8 7.8 7.1 1.8 1 1 0 1 1 1 0 TMIE protein GP41 PF00517.17 OQR91625.1 - 7.5 6.4 9.7 0.24 11.3 2.1 1.9 1 1 1 2 2 2 0 Retroviral envelope protein Glyco_transf_41 PF13844.6 OQR91626.1 - 2.8e-83 279.9 1.4 7.9e-41 140.0 0.2 2.1 1 1 1 2 2 2 2 Glycosyl transferase family 41 Methyltransf_11 PF08241.12 OQR91626.1 - 9e-07 29.5 0.0 3e-05 24.6 0.0 2.6 2 0 0 2 2 2 1 Methyltransferase domain TPR_16 PF13432.6 OQR91626.1 - 2e-05 25.1 0.0 0.00016 22.2 0.0 2.3 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.28 OQR91626.1 - 0.00032 20.4 0.0 0.054 13.3 0.0 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat Methyltransf_23 PF13489.6 OQR91626.1 - 0.017 14.9 0.0 0.036 13.9 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain TPR_19 PF14559.6 OQR91626.1 - 0.022 15.2 0.1 0.44 11.1 0.0 2.8 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 OQR91626.1 - 0.024 15.4 0.0 0.23 12.4 0.0 2.4 1 1 1 2 2 2 0 Tetratricopeptide repeat Methyltransf_25 PF13649.6 OQR91626.1 - 0.027 15.2 0.0 0.84 10.4 0.0 2.5 2 0 0 2 2 2 0 Methyltransferase domain TPR_8 PF13181.6 OQR91626.1 - 0.031 14.5 0.0 2.2 8.7 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 OQR91626.1 - 0.031 14.4 0.0 5.8 7.3 0.0 2.8 3 0 0 3 3 2 0 Tetratricopeptide repeat BK_channel_a PF03493.18 OQR91626.1 - 0.047 13.9 0.1 0.51 10.6 0.0 2.7 2 1 0 2 2 2 0 Calcium-activated BK potassium channel alpha subunit ApbA PF02558.16 OQR91626.1 - 0.1 12.3 0.0 2.5 7.7 0.0 2.3 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA TPR_12 PF13424.6 OQR91626.1 - 0.1 12.9 0.1 11 6.4 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat HECT PF00632.25 OQR91627.1 - 2.6e-61 207.8 0.0 7.2e-61 206.3 0.0 1.7 2 0 0 2 2 2 1 HECT-domain (ubiquitin-transferase) MIB_HERC2 PF06701.13 OQR91627.1 - 6.4e-14 52.0 0.4 2.4e-13 50.1 0.4 2.1 1 0 0 1 1 1 1 Mib_herc2 SPRY PF00622.28 OQR91627.1 - 6.1e-11 42.5 0.0 1.8e-10 40.9 0.0 1.8 1 0 0 1 1 1 1 SPRY domain Laminin_G_3 PF13385.6 OQR91627.1 - 2.8e-09 37.3 0.0 5.3e-09 36.4 0.0 1.4 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily DUF1583 PF07622.11 OQR91627.1 - 0.15 10.8 0.0 0.29 9.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1583) DUF1765 PF08578.10 OQR91628.1 - 1.1e-20 74.4 2.0 3.2e-20 72.9 2.0 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF1765) C2 PF00168.30 OQR91628.1 - 1.4e-10 41.4 0.0 3.6e-10 40.0 0.0 1.7 1 0 0 1 1 1 1 C2 domain PH PF00169.29 OQR91628.1 - 1.4e-09 38.4 0.2 1.4e-08 35.1 0.1 2.5 2 0 0 2 2 2 1 PH domain DUF1825 PF08855.10 OQR91628.1 - 0.011 15.6 0.0 0.032 14.1 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1825) Med3 PF11593.8 OQR91628.1 - 0.072 12.3 2.9 0.13 11.5 2.9 1.3 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Med9 PF07544.13 OQR91650.1 - 0.00024 21.1 3.0 0.00024 21.1 3.0 4.8 3 1 2 6 6 6 1 RNA polymerase II transcription mediator complex subunit 9 AAA_13 PF13166.6 OQR91650.1 - 0.0019 17.0 7.8 0.0019 17.0 7.8 2.3 1 1 1 2 2 2 1 AAA domain Paramyx_P_V_C PF03210.13 OQR91650.1 - 0.0076 16.1 0.1 0.0076 16.1 0.1 2.8 3 1 0 3 3 3 1 Paramyxovirus P/V phosphoprotein C-terminal ATG16 PF08614.11 OQR91650.1 - 0.029 14.6 38.9 0.12 12.6 22.6 3.7 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) KCNQC3-Ank-G_bd PF11956.8 OQR91650.1 - 0.05 13.9 0.0 0.13 12.5 0.0 1.7 1 0 0 1 1 1 0 Ankyrin-G binding motif of KCNQ2-3 MH1 PF03165.16 OQR91650.1 - 0.29 11.4 3.7 1.1 9.6 1.4 2.7 1 1 1 2 2 2 0 MH1 domain DUF16 PF01519.16 OQR91650.1 - 0.42 11.1 28.5 2.7 8.5 0.7 4.2 1 1 1 3 3 3 0 Protein of unknown function DUF16 Lzipper-MIP1 PF14389.6 OQR91650.1 - 0.45 10.9 24.8 0.25 11.6 6.3 4.2 2 1 2 4 4 4 0 Leucine-zipper of ternary complex factor MIP1 NPV_P10 PF05531.12 OQR91650.1 - 2.7 8.5 15.8 1.1 9.7 2.1 4.5 5 2 1 6 6 6 0 Nucleopolyhedrovirus P10 protein UCH PF00443.29 OQR91650.1 - 3.2 7.2 8.7 4.1 6.8 8.0 1.6 1 1 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase Fib_alpha PF08702.10 OQR91650.1 - 4.1 7.6 31.1 3 8.0 12.2 4.2 1 1 3 4 4 4 0 Fibrinogen alpha/beta chain family DUF1664 PF07889.12 OQR91650.1 - 4.6 7.3 23.4 2 8.5 1.1 4.0 2 1 2 4 4 4 0 Protein of unknown function (DUF1664) DUF4407 PF14362.6 OQR91650.1 - 5 6.4 28.5 0.98 8.7 6.6 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) Ank_3 PF13606.6 OQR91651.1 - 1.1e-05 25.4 0.6 0.18 12.5 0.0 3.3 2 1 1 3 3 3 2 Ankyrin repeat Ank_2 PF12796.7 OQR91651.1 - 0.00014 22.4 1.9 0.00033 21.2 1.6 1.8 2 1 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OQR91651.1 - 0.00019 21.6 1.9 0.62 10.5 0.0 3.2 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 OQR91651.1 - 0.00024 21.6 1.1 0.00089 19.8 0.1 2.4 2 1 0 2 2 2 1 Ankyrin repeats (many copies) Exo_endo_phos PF03372.23 OQR91652.1 - 0.016 14.7 0.0 0.063 12.8 0.0 1.9 1 1 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family ABC_membrane PF00664.23 OQR91669.1 - 1.8e-18 67.2 23.0 2.2e-18 66.9 23.0 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 OQR91669.1 - 1e-05 26.1 0.2 2e-05 25.1 0.2 1.5 1 0 0 1 1 1 1 ABC transporter RsgA_GTPase PF03193.16 OQR91669.1 - 0.021 14.7 0.4 0.045 13.7 0.0 1.7 2 0 0 2 2 2 0 RsgA GTPase Dynamin_N PF00350.23 OQR91669.1 - 0.12 12.4 0.2 0.25 11.4 0.2 1.5 1 0 0 1 1 1 0 Dynamin family MMR_HSR1 PF01926.23 OQR91669.1 - 0.16 12.1 0.1 0.37 10.9 0.1 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase Tmemb_18A PF09771.9 OQR91669.1 - 1.5 9.2 5.8 4.3 7.7 2.4 2.5 2 0 0 2 2 2 0 Transmembrane protein 188 Ank_5 PF13857.6 OQR91670.1 - 1e-21 76.7 5.1 0.0053 17.1 0.3 7.5 3 1 5 8 8 8 7 Ankyrin repeats (many copies) Ank_2 PF12796.7 OQR91670.1 - 7.7e-20 71.3 6.8 5.5e-07 30.1 0.2 4.5 1 1 3 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQR91670.1 - 2e-18 66.5 6.0 8.5e-05 23.0 0.1 6.5 5 1 2 7 7 7 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQR91670.1 - 9.1e-14 50.2 2.7 2.5 9.0 0.0 7.9 6 1 2 8 8 8 5 Ankyrin repeat DUF5049 PF16468.5 OQR91670.1 - 0.00013 21.8 0.1 2.2 8.2 0.0 4.5 3 1 2 5 5 5 2 Domain of unknown function (DUF5049) Ank PF00023.30 OQR91670.1 - 0.00076 19.8 5.7 56 4.4 0.0 6.8 2 2 5 7 7 7 0 Ankyrin repeat DLH PF01738.18 OQR91671.1 - 2.9e-16 59.7 0.0 3.5e-16 59.4 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_1 PF00561.20 OQR91671.1 - 0.0036 17.0 0.0 0.005 16.5 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 OQR91671.1 - 0.0076 15.5 0.0 0.064 12.5 0.0 2.0 1 1 1 2 2 2 1 Serine aminopeptidase, S33 Pkinase PF00069.25 OQR91672.1 - 2.9e-29 102.2 0.1 6.5e-29 101.1 0.1 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQR91672.1 - 4.3e-25 88.5 0.1 2.4e-24 86.0 0.1 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Crystall PF00030.19 OQR91672.1 - 0.0074 16.5 0.5 0.034 14.4 0.6 2.1 1 1 0 1 1 1 1 Beta/Gamma crystallin Pkinase_fungal PF17667.1 OQR91672.1 - 0.11 11.2 0.0 0.17 10.6 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase FTA2 PF13095.6 OQR91672.1 - 0.12 12.0 0.1 5.5 6.6 0.0 2.2 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 OQR91672.1 - 0.18 11.1 0.0 0.32 10.3 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Dpy-30 PF05186.13 OQR91682.1 - 0.002 17.8 0.1 0.0051 16.5 0.1 1.7 1 1 0 1 1 1 1 Dpy-30 motif TyrRSs_C PF16714.5 OQR91682.1 - 0.024 14.5 0.0 0.04 13.7 0.0 1.3 1 0 0 1 1 1 0 Tyrosyl-tRNA synthetase C-terminal domain ASH PF15780.5 OQR91684.1 - 3.5e-08 33.6 0.3 0.0039 17.4 0.0 2.4 2 0 0 2 2 2 2 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin PapD-like PF14874.6 OQR91684.1 - 1.6e-06 28.2 0.2 5.8e-06 26.4 0.2 1.9 1 0 0 1 1 1 1 Flagellar-associated PapD-like TMEM131_like PF12371.8 OQR91684.1 - 0.0011 19.2 0.9 0.076 13.3 0.1 3.2 3 0 0 3 3 3 1 Transmembrane protein 131-like EF-hand_1 PF00036.32 OQR91685.1 - 3.8e-14 51.1 0.1 1.9e-06 27.0 0.0 2.9 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 OQR91685.1 - 2.4e-12 45.7 3.9 4.5e-05 23.1 0.9 3.0 2 1 1 3 3 3 2 EF-hand domain EF-hand_7 PF13499.6 OQR91685.1 - 8.8e-12 45.3 0.1 8.8e-12 45.3 0.1 2.2 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_8 PF13833.6 OQR91685.1 - 1.3e-11 44.2 0.1 4.3e-11 42.5 0.1 2.0 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.6 OQR91685.1 - 2.3e-11 42.6 3.4 2.5e-05 23.6 0.1 3.6 3 0 0 3 3 3 2 EF hand SPARC_Ca_bdg PF10591.9 OQR91685.1 - 0.062 13.6 0.3 0.15 12.4 0.3 1.7 1 0 0 1 1 1 0 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_9 PF14658.6 OQR91685.1 - 0.063 13.6 0.0 0.18 12.2 0.0 1.7 1 0 0 1 1 1 0 EF-hand domain EF-hand_4 PF12763.7 OQR91685.1 - 0.087 12.8 0.2 0.23 11.4 0.1 1.8 1 1 0 1 1 1 0 Cytoskeletal-regulatory complex EF hand CBFD_NFYB_HMF PF00808.23 OQR91686.1 - 9.9e-22 77.0 0.1 2.8e-21 75.6 0.1 1.8 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 OQR91686.1 - 1.8e-16 60.7 0.7 5.8e-16 59.1 0.7 1.9 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 WW PF00397.26 OQR91687.1 - 4e-30 103.6 37.6 2.3e-07 30.8 1.6 5.9 6 0 0 6 6 6 5 WW domain IQ PF00612.27 OQR91687.1 - 1.6e-12 46.0 21.0 0.0069 16.1 1.3 5.9 5 0 0 5 5 5 5 IQ calmodulin-binding motif zf-C2H2 PF00096.26 OQR91687.1 - 0.0012 19.2 1.1 0.0012 19.2 1.1 3.3 4 0 0 4 4 4 1 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 OQR91687.1 - 0.0067 16.7 0.3 0.027 14.7 0.3 2.2 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.12 OQR91687.1 - 0.0076 16.5 3.3 0.03 14.6 3.3 2.1 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_4 PF13894.6 OQR91687.1 - 0.015 16.1 0.9 0.015 16.1 0.9 3.6 4 0 0 4 4 4 0 C2H2-type zinc finger Glyco_hyd_101C PF17451.2 OQR91687.1 - 0.12 12.6 0.1 0.12 12.6 0.1 4.4 3 1 2 5 5 5 0 Glycosyl hydrolase 101 beta sandwich domain DUF5111 PF17138.4 OQR91687.1 - 0.21 11.5 4.9 1.9 8.3 0.0 3.3 4 0 0 4 4 4 0 Domain of unknown function (DUF5111) zf-BED PF02892.15 OQR91687.1 - 0.65 10.1 6.6 0.63 10.1 3.8 2.5 2 0 0 2 2 2 0 BED zinc finger AMP-binding PF00501.28 OQR91688.1 - 1.5e-69 234.6 0.0 2.8e-69 233.7 0.0 1.4 2 0 0 2 2 2 1 AMP-binding enzyme AMP-binding_C PF13193.6 OQR91688.1 - 0.00017 22.5 0.0 0.00039 21.3 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain zf-C2H2 PF00096.26 OQR91689.1 - 0.7 10.5 21.0 2.2 8.9 0.1 5.4 5 0 0 5 5 5 0 Zinc finger, C2H2 type zf-C2H2_6 PF13912.6 OQR91689.1 - 1.6 8.8 7.1 6.4 6.9 1.0 3.5 2 1 1 3 3 3 0 C2H2-type zinc finger Arc_trans_TRASH PF08394.10 OQR91689.1 - 6 7.3 8.3 0.39 11.1 2.1 2.2 2 0 0 2 2 2 0 Archaeal TRASH domain Hat1_N PF10394.9 OQR91690.1 - 1.1e-35 123.3 1.3 1.6e-35 122.7 0.7 1.6 2 0 0 2 2 2 1 Histone acetyl transferase HAT1 N-terminus Acetyltransf_1 PF00583.25 OQR91690.1 - 2.1e-07 31.2 0.0 5.8e-07 29.8 0.0 1.8 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 OQR91690.1 - 7e-06 26.0 0.0 3.1e-05 23.9 0.0 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 OQR91690.1 - 0.00037 20.9 0.0 0.00078 19.8 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 OQR91690.1 - 0.0042 17.2 0.0 0.013 15.5 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 OQR91690.1 - 0.057 13.4 0.0 0.19 11.7 0.0 1.9 2 0 0 2 2 2 0 FR47-like protein MOZ_SAS PF01853.18 OQR91690.1 - 0.11 12.2 0.0 0.2 11.3 0.0 1.5 1 0 0 1 1 1 0 MOZ/SAS family RNA_pol_Rpb2_6 PF00562.28 OQR91691.1 - 4.3e-63 213.7 0.0 7e-63 213.0 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 OQR91691.1 - 1.1e-54 185.0 0.0 1.6e-54 184.5 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.14 OQR91691.1 - 1.6e-22 80.0 0.2 3.2e-22 79.1 0.2 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_3 PF04565.16 OQR91691.1 - 2.5e-21 75.6 0.1 7.4e-21 74.1 0.0 1.9 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_4 PF04566.13 OQR91691.1 - 3.2e-19 69.0 1.1 8.7e-19 67.6 1.1 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_5 PF04567.17 OQR91691.1 - 6.3e-11 42.7 0.6 2e-10 41.1 0.6 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 Hexapep PF00132.24 OQR91697.1 - 7.2e-10 38.2 10.8 9.1e-06 25.2 3.9 4.4 3 1 1 4 4 4 2 Bacterial transferase hexapeptide (six repeats) Fucokinase PF07959.12 OQR91697.1 - 0.012 14.5 1.2 0.022 13.7 1.2 1.5 1 1 0 1 1 1 0 L-fucokinase Hexapep_2 PF14602.6 OQR91697.1 - 0.039 13.7 14.8 0.084 12.6 4.6 3.9 3 1 1 4 4 4 0 Hexapeptide repeat of succinyl-transferase Corona_NS1 PF06145.11 OQR91697.1 - 0.13 11.8 0.1 0.27 10.8 0.1 1.4 1 0 0 1 1 1 0 Coronavirus nonstructural protein NS1 SHIPPO-rpt PF07004.12 OQR91698.1 - 2.9e-11 43.7 12.0 0.9 10.6 0.3 7.1 7 0 0 7 7 7 6 Sperm-tail PG-rich repeat Stealth_CR3 PF17102.5 OQR91699.1 - 1.3e-17 63.4 5.7 4.2e-17 61.8 4.1 2.4 2 0 0 2 2 2 1 Stealth protein CR3, conserved region 3 Stealth_CR4 PF17103.5 OQR91699.1 - 7.4e-14 51.4 0.1 1.9e-13 50.1 0.1 1.7 1 0 0 1 1 1 1 Stealth protein CR4, conserved region 4 RabGAP-TBC PF00566.18 OQR91709.1 - 1.5e-29 103.2 0.0 3e-29 102.2 0.0 1.5 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Ank_2 PF12796.7 OQR91709.1 - 2.6e-22 79.2 0.2 8.1e-14 52.0 0.5 2.6 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQR91709.1 - 6.9e-16 58.4 8.2 4e-08 33.6 1.5 5.3 3 1 3 6 6 6 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 OQR91709.1 - 1e-14 54.3 7.2 0.00067 19.9 0.1 5.7 2 1 3 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQR91709.1 - 3.3e-11 42.4 5.8 0.1 13.2 0.2 5.7 5 0 0 5 5 5 3 Ankyrin repeat Ank PF00023.30 OQR91709.1 - 6.7e-07 29.5 6.3 0.031 14.7 1.2 4.8 3 1 1 4 4 4 2 Ankyrin repeat fn3 PF00041.21 OQR91709.1 - 7.1e-05 23.1 0.0 0.00052 20.3 0.0 2.2 2 0 0 2 2 2 1 Fibronectin type III domain SAM_2 PF07647.17 OQR91709.1 - 0.083 13.0 0.0 0.3 11.2 0.0 1.9 2 0 0 2 2 2 0 SAM domain (Sterile alpha motif) Atx10homo_assoc PF09759.9 OQR91710.1 - 3.6e-26 91.1 4.4 6.8e-16 58.1 0.1 4.4 4 0 0 4 4 4 3 Spinocerebellar ataxia type 10 protein domain DUF525 PF04379.14 OQR91728.1 - 5.1e-19 68.3 0.0 8.2e-19 67.6 0.0 1.3 1 0 0 1 1 1 1 ApaG domain Complex1_LYR PF05347.15 OQR91728.1 - 9.4e-05 22.4 1.2 0.0055 16.7 0.0 2.8 3 0 0 3 3 3 1 Complex 1 protein (LYR family) zf-CCHC_3 PF13917.6 OQR91729.1 - 5.4e-08 32.7 0.1 1.7e-07 31.1 0.1 1.9 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.23 OQR91729.1 - 0.0092 16.0 1.4 0.02 15.0 1.4 1.6 1 0 0 1 1 1 1 Zinc knuckle ORC6 PF05460.13 OQR91729.1 - 0.06 12.6 21.7 0.08 12.2 21.7 1.1 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) LAP1C PF05609.12 OQR91729.1 - 1.6 7.8 19.7 1.6 7.7 19.7 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) SSP160 PF06933.11 OQR91729.1 - 3.2 5.9 7.4 4.2 5.5 7.4 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Hid1 PF12722.7 OQR91729.1 - 7.8 4.5 19.9 8.2 4.4 19.9 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF4603 PF15376.6 OQR91729.1 - 8.2 3.7 28.5 7.9 3.7 28.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4603) Malic_M PF03949.15 OQR91730.1 - 1.5e-95 319.4 0.6 1.9e-95 319.0 0.6 1.1 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.19 OQR91730.1 - 1.3e-74 250.0 0.0 2e-74 249.3 0.0 1.3 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain Pyr_redox_2 PF07992.14 OQR91730.1 - 0.1 11.8 0.1 0.2 10.8 0.1 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase ERG4_ERG24 PF01222.17 OQR91734.1 - 9.6e-132 439.8 13.5 1.3e-131 439.3 13.5 1.2 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DEAD PF00270.29 OQR91734.1 - 2.1e-45 154.6 0.7 7.2e-45 152.9 0.0 2.2 3 0 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OQR91734.1 - 4.9e-22 78.4 0.0 1.5e-21 76.8 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 OQR91734.1 - 2.4e-15 56.5 0.2 7.4e-15 54.9 0.2 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 OQR91734.1 - 3.9e-07 30.2 3.7 1e-06 28.9 0.0 2.6 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit DUF1295 PF06966.12 OQR91734.1 - 0.01 15.3 0.1 0.021 14.4 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1295) CENP-O PF09496.10 OQR91734.1 - 8.2 6.3 10.9 5.7 6.9 8.7 1.9 1 1 1 2 2 2 0 Cenp-O kinetochore centromere component PCMT PF01135.19 OQR91735.1 - 2.2e-41 141.9 0.0 2.9e-41 141.5 0.0 1.1 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.6 OQR91735.1 - 1.9e-11 44.0 0.0 3.6e-11 43.1 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OQR91735.1 - 6.7e-11 42.8 0.0 1.6e-10 41.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OQR91735.1 - 1.2e-09 38.2 0.0 1.7e-09 37.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OQR91735.1 - 1.8e-09 38.1 0.0 3.2e-09 37.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 OQR91735.1 - 2.4e-09 36.9 0.0 3.5e-09 36.3 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family PrmA PF06325.13 OQR91735.1 - 1.6e-08 34.3 0.1 2.4e-08 33.7 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_32 PF13679.6 OQR91735.1 - 1.2e-06 28.7 0.1 2e-06 27.9 0.0 1.5 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OQR91735.1 - 1.2e-06 29.1 0.0 2.4e-06 28.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 OQR91735.1 - 1.5e-06 27.8 0.0 2.9e-06 27.0 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_18 PF12847.7 OQR91735.1 - 3.8e-05 23.7 0.0 6.4e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain NodS PF05401.11 OQR91735.1 - 6.1e-05 22.7 0.0 9.7e-05 22.1 0.0 1.3 1 0 0 1 1 1 1 Nodulation protein S (NodS) Drc1-Sld2 PF11719.8 OQR91735.1 - 0.00055 19.6 0.0 0.00071 19.2 0.0 1.1 1 0 0 1 1 1 1 DNA replication and checkpoint protein Methyltransf_3 PF01596.17 OQR91735.1 - 0.001 18.3 0.0 0.0015 17.8 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_9 PF08003.11 OQR91735.1 - 0.0019 17.2 0.0 0.0041 16.1 0.0 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF1698) AviRa PF11599.8 OQR91735.1 - 0.0041 16.6 0.0 0.0061 16.0 0.0 1.3 1 0 0 1 1 1 1 RRNA methyltransferase AviRa CMAS PF02353.20 OQR91735.1 - 0.0057 16.0 0.0 0.0085 15.4 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Met_10 PF02475.16 OQR91735.1 - 0.018 14.8 0.0 0.024 14.4 0.0 1.2 1 0 0 1 1 1 0 Met-10+ like-protein FtsJ PF01728.19 OQR91735.1 - 0.022 14.8 0.0 0.049 13.8 0.0 1.5 1 1 0 1 1 1 0 FtsJ-like methyltransferase Borealin PF10512.9 OQR91735.1 - 0.056 13.4 0.3 0.12 12.4 0.0 1.6 2 0 0 2 2 1 0 Cell division cycle-associated protein 8 Thioredoxin PF00085.20 OQR91736.1 - 4.2e-25 87.7 0.1 4.8e-25 87.5 0.1 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 OQR91736.1 - 1.2e-05 25.7 0.2 0.0004 20.8 0.2 2.1 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_9 PF14595.6 OQR91736.1 - 0.00031 20.5 0.0 0.00033 20.4 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 OQR91736.1 - 0.00052 20.3 0.0 0.0038 17.5 0.0 2.0 1 1 1 2 2 2 1 Thioredoxin-like Phosducin PF02114.16 OQR91736.1 - 0.0042 16.1 0.0 0.0047 15.9 0.0 1.0 1 0 0 1 1 1 1 Phosducin Redoxin PF08534.10 OQR91736.1 - 0.02 14.6 0.2 0.09 12.5 0.1 1.8 1 1 1 2 2 2 0 Redoxin Thioredoxin_5 PF13743.6 OQR91736.1 - 0.11 12.1 0.2 6.1 6.5 0.1 2.1 1 1 1 2 2 2 0 Thioredoxin OST3_OST6 PF04756.13 OQR91736.1 - 0.14 11.5 0.0 0.15 11.4 0.0 1.2 1 0 0 1 1 1 0 OST3 / OST6 family, transporter family GIT_SHD PF08518.11 OQR91736.1 - 0.18 11.5 4.5 6.1 6.6 0.1 2.8 3 0 0 3 3 3 0 Spa2 homology domain (SHD) of GIT TPR_14 PF13428.6 OQR91737.1 - 0.00016 22.2 0.6 0.0077 17.0 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat NRDE-2 PF08424.10 OQR91737.1 - 0.00079 18.6 0.4 0.0045 16.2 0.0 2.1 2 0 0 2 2 2 1 NRDE-2, necessary for RNA interference AAA_lid_6 PF17866.1 OQR91737.1 - 0.022 15.0 0.0 0.69 10.1 0.0 2.7 2 0 0 2 2 2 0 AAA lid domain Suf PF05843.14 OQR91737.1 - 0.042 13.8 0.5 1.8 8.5 0.0 2.7 2 1 0 2 2 2 0 Suppressor of forked protein (Suf) Nuc_sug_transp PF04142.15 OQR91756.1 - 2.3e-20 73.0 16.3 3.4e-20 72.4 16.3 1.2 1 0 0 1 1 1 1 Nucleotide-sugar transporter PUNUT PF16913.5 OQR91756.1 - 8.4e-08 31.8 7.4 8.4e-08 31.8 7.4 1.6 2 0 0 2 2 2 1 Purine nucleobase transmembrane transport EamA PF00892.20 OQR91756.1 - 0.00037 20.7 6.6 0.00037 20.7 6.6 2.5 2 1 0 2 2 2 1 EamA-like transporter family DUF758 PF05527.11 OQR91756.1 - 0.027 14.4 1.0 0.043 13.8 0.2 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF758) AAA_6 PF12774.7 OQR91757.1 - 5.8e-143 475.8 0.0 1.4e-142 474.5 0.0 1.7 1 0 0 1 1 1 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 OQR91757.1 - 3.5e-129 431.4 4.3 3.5e-129 431.4 4.3 2.6 2 1 0 2 2 2 1 Dynein heavy chain, N-terminal region 2 AAA_8 PF12780.7 OQR91757.1 - 6.4e-85 284.6 0.3 2.5e-83 279.4 0.0 2.8 2 0 0 2 2 2 1 P-loop containing dynein motor region D4 AAA_7 PF12775.7 OQR91757.1 - 5e-66 221.7 1.8 3.2e-60 202.7 0.0 4.8 5 0 0 5 5 5 1 P-loop containing dynein motor region AAA_5 PF07728.14 OQR91757.1 - 7.7e-17 61.6 0.0 0.02 14.9 0.0 5.9 4 1 0 4 4 4 4 AAA domain (dynein-related subfamily) AAA_lid_1 PF17857.1 OQR91757.1 - 6.2e-15 55.2 0.0 2.4e-14 53.3 0.0 2.1 1 0 0 1 1 1 1 AAA+ lid domain Dynein_AAA_lid PF17852.1 OQR91757.1 - 7.4e-14 51.9 3.4 9.4e-14 51.6 0.5 2.9 2 0 0 2 2 2 1 Dynein heavy chain AAA lid domain AAA PF00004.29 OQR91757.1 - 4e-11 43.5 2.5 0.026 14.9 0.0 5.1 4 0 0 4 4 4 3 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 OQR91757.1 - 1.7e-10 41.3 0.3 0.026 14.8 0.1 5.1 4 0 0 4 4 4 2 AAA domain AAA_18 PF13238.6 OQR91757.1 - 2.4e-08 34.6 1.5 0.073 13.6 0.0 5.4 5 0 0 5 5 5 2 AAA domain AAA_16 PF13191.6 OQR91757.1 - 8.5e-07 29.5 0.1 3.8 7.8 0.0 5.2 4 0 0 4 4 4 2 AAA ATPase domain T2SSE PF00437.20 OQR91757.1 - 0.00014 21.0 0.8 0.75 8.8 0.0 3.5 4 0 0 4 4 4 2 Type II/IV secretion system protein NACHT PF05729.12 OQR91757.1 - 0.0016 18.4 0.5 0.27 11.2 0.0 3.8 3 0 0 3 3 3 1 NACHT domain RNA_helicase PF00910.22 OQR91757.1 - 0.0018 18.6 0.2 16 5.9 0.0 4.1 3 0 0 3 3 3 0 RNA helicase Sigma54_activat PF00158.26 OQR91757.1 - 0.002 17.9 0.4 0.75 9.5 0.0 3.8 4 0 0 4 4 4 1 Sigma-54 interaction domain Apolipoprotein PF01442.18 OQR91757.1 - 0.0038 17.1 0.6 0.14 12.0 0.1 3.2 2 1 0 2 2 2 1 Apolipoprotein A1/A4/E domain Sigma54_activ_2 PF14532.6 OQR91757.1 - 0.0047 17.0 0.3 0.36 10.9 0.0 3.2 3 0 0 3 3 2 1 Sigma-54 interaction domain AAA_24 PF13479.6 OQR91757.1 - 0.0064 16.2 0.6 1.2 8.8 0.0 3.9 3 0 0 3 3 3 1 AAA domain TsaE PF02367.17 OQR91757.1 - 0.0078 16.2 1.3 11 6.0 0.1 3.9 3 0 0 3 3 3 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_29 PF13555.6 OQR91757.1 - 0.013 15.2 2.8 6.6 6.6 0.1 3.7 3 0 0 3 3 3 0 P-loop containing region of AAA domain APS_kinase PF01583.20 OQR91757.1 - 0.02 14.8 0.6 11 5.9 0.0 3.1 3 0 0 3 3 3 0 Adenylylsulphate kinase AAA_30 PF13604.6 OQR91757.1 - 0.026 14.3 4.6 14 5.3 0.1 4.1 4 0 0 4 4 4 0 AAA domain Zeta_toxin PF06414.12 OQR91757.1 - 0.42 9.9 2.2 27 3.9 0.1 3.7 4 0 0 4 4 4 0 Zeta toxin SRP54 PF00448.22 OQR91757.1 - 0.46 10.1 3.3 26 4.4 0.1 3.4 3 0 0 3 3 3 0 SRP54-type protein, GTPase domain AAA_33 PF13671.6 OQR91757.1 - 0.6 10.3 5.6 14 5.8 0.1 3.8 4 0 0 4 4 4 0 AAA domain NTPase_1 PF03266.15 OQR91757.1 - 0.79 9.6 6.2 4.6 7.1 0.1 3.1 3 0 0 3 3 3 0 NTPase AAA_28 PF13521.6 OQR91757.1 - 2.1 8.6 10.7 2.9 8.1 0.9 4.1 4 0 0 4 4 4 0 AAA domain Mg_chelatase PF01078.21 OQR91757.1 - 5.6 6.3 7.1 13 5.1 0.1 4.0 5 0 0 5 5 4 0 Magnesium chelatase, subunit ChlI RRT14 PF17075.5 OQR91758.1 - 0.021 14.9 2.6 1.3 9.1 0.2 2.3 2 0 0 2 2 2 0 Regular of rDNA transcription protein 14 DUF4890 PF16231.5 OQR91758.1 - 0.027 14.9 1.4 0.027 14.9 1.4 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4890) TraI PF07057.11 OQR91758.1 - 0.071 13.2 0.1 7.5 6.7 0.1 2.4 2 0 0 2 2 2 0 DNA helicase TraI DUF2062 PF09835.9 OQR91759.1 - 8.3e-15 54.9 4.7 9.2e-15 54.8 4.7 1.0 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2062) Sugar_tr PF00083.24 OQR91760.1 - 6.1e-114 381.4 31.1 1.1e-87 294.8 16.8 2.0 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 OQR91760.1 - 2.7e-36 125.2 28.6 2.2e-32 112.4 18.5 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily DUF2238 PF09997.9 OQR91760.1 - 0.19 11.5 0.1 0.19 11.5 0.1 2.8 3 0 0 3 3 3 0 Predicted membrane protein (DUF2238) PSI PF01437.25 OQR91760.1 - 6.9 7.3 7.3 11 6.6 7.3 1.3 1 0 0 1 1 1 0 Plexin repeat COG4 PF08318.12 OQR91761.1 - 5.9e-26 91.3 2.6 1.8e-25 89.7 2.6 1.8 1 1 0 1 1 1 1 COG4 transport protein RINT1_TIP1 PF04437.13 OQR91761.1 - 2.4e-06 26.7 0.0 5e-06 25.7 0.0 1.5 1 0 0 1 1 1 1 RINT-1 / TIP-1 family Sec15 PF04091.12 OQR91761.1 - 0.00025 20.5 0.1 0.00079 18.9 0.1 1.9 1 0 0 1 1 1 1 Exocyst complex subunit Sec15-like Dimerisation2 PF16864.5 OQR91761.1 - 0.01 15.8 0.6 0.092 12.7 0.1 2.6 2 0 0 2 2 2 0 Dimerisation domain Ribosomal_60s PF00428.19 OQR91761.1 - 0.77 10.4 4.8 0.22 12.1 0.8 2.1 2 0 0 2 2 2 0 60s Acidic ribosomal protein Yip1 PF04893.17 OQR91762.1 - 3e-17 62.9 16.4 3.9e-17 62.5 16.4 1.2 1 0 0 1 1 1 1 Yip1 domain Calci_bind_CcbP PF11535.8 OQR91762.1 - 0.15 12.6 0.0 0.23 11.9 0.0 1.3 1 0 0 1 1 1 0 Calcium binding Globin PF00042.22 OQR91763.1 - 0.0011 19.5 0.3 0.0065 17.0 0.3 2.2 1 1 0 1 1 1 1 Globin CBM_1 PF00734.18 OQR91782.1 - 4.2e-13 49.0 22.5 6.6e-08 32.4 6.8 4.5 5 0 0 5 5 5 2 Fungal cellulose binding domain PAN_4 PF14295.6 OQR91782.1 - 0.0067 16.3 2.1 0.0067 16.3 2.1 4.6 4 1 0 5 5 5 1 PAN domain PMP22_Claudin PF00822.20 OQR91782.1 - 1.2 9.0 5.5 7 6.5 2.0 2.9 2 1 0 2 2 2 0 PMP-22/EMP/MP20/Claudin family CBM_1 PF00734.18 OQR91783.1 - 1.3e-19 69.8 26.3 1.4e-11 44.1 7.7 4.7 5 0 0 5 5 5 2 Fungal cellulose binding domain DUF572 PF04502.13 OQR91783.1 - 0.011 15.3 2.7 0.016 14.9 2.7 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) Glyco_hydro_18 PF00704.28 OQR91784.1 - 6.2e-55 187.1 0.3 7.3e-55 186.9 0.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Inhibitor_G39P PF11417.8 OQR91784.1 - 0.057 13.9 0.1 0.42 11.2 0.0 2.5 2 0 0 2 2 2 0 Loader and inhibitor of phage G40P PHR PF08005.12 OQR91784.1 - 0.13 12.9 0.1 0.23 12.1 0.1 1.3 1 0 0 1 1 1 0 PHR domain Glyco_hydro_18 PF00704.28 OQR91785.1 - 4.3e-108 361.7 3.6 1.7e-53 182.4 0.3 2.0 2 0 0 2 2 2 2 Glycosyl hydrolases family 18 PHR PF08005.12 OQR91785.1 - 0.00058 20.5 0.1 1.4 9.6 0.0 2.3 2 0 0 2 2 2 2 PHR domain DUF5643 PF18705.1 OQR91785.1 - 0.009 16.0 0.0 0.99 9.4 0.0 2.4 2 0 0 2 2 2 2 Family of unknown function (DUF5643) TcpQ PF10671.9 OQR91785.1 - 0.02 15.0 0.1 12 6.1 0.0 2.6 2 0 0 2 2 2 0 Toxin co-regulated pilus biosynthesis protein Q Vta1 PF04652.16 OQR91799.1 - 9e-45 152.2 0.4 1.8e-44 151.2 0.4 1.5 1 0 0 1 1 1 1 Vta1 like Cellulase PF00150.18 OQR91799.1 - 3.2e-31 108.8 1.5 4.3e-31 108.4 1.5 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Vta1_C PF18097.1 OQR91799.1 - 0.00029 20.5 2.6 0.00056 19.6 0.9 2.3 2 0 0 2 2 2 1 Vta1 C-terminal domain tRNA_m1G_MT PF01746.21 OQR91800.1 - 1.7e-26 93.1 0.0 2.9e-26 92.4 0.0 1.4 1 1 0 1 1 1 1 tRNA (Guanine-1)-methyltransferase Myb_DNA-binding PF00249.31 OQR91801.1 - 0.095 12.9 0.0 0.17 12.1 0.0 1.4 1 0 0 1 1 1 0 Myb-like DNA-binding domain G-patch_2 PF12656.7 OQR91803.1 - 3e-17 62.4 0.1 3e-17 62.4 0.1 3.2 3 1 0 3 3 3 1 G-patch domain V_ATPase_I PF01496.19 OQR91803.1 - 4 5.2 3.6 5.1 4.9 3.6 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family PI3_PI4_kinase PF00454.27 OQR91804.1 - 2.2e-25 89.9 0.0 3.3e-14 53.3 0.0 2.7 1 1 1 2 2 2 2 Phosphatidylinositol 3- and 4-kinase Ribonuclease_T2 PF00445.18 OQR91804.1 - 1.1e-20 74.6 0.5 2.5e-20 73.5 0.5 1.6 1 0 0 1 1 1 1 Ribonuclease T2 family PH PF00169.29 OQR91804.1 - 5.8e-15 55.7 0.3 2.1e-14 53.9 0.1 2.1 2 0 0 2 2 2 1 PH domain PH_9 PF15410.6 OQR91804.1 - 0.027 14.8 0.5 0.49 10.8 0.5 2.5 1 1 0 1 1 1 0 Pleckstrin homology domain PH_11 PF15413.6 OQR91804.1 - 0.18 12.2 1.5 0.94 9.9 1.5 2.2 1 1 0 1 1 1 0 Pleckstrin homology domain DUF2048 PF09752.9 OQR91805.1 - 7.8e-63 212.7 0.0 9.2e-63 212.5 0.0 1.0 1 0 0 1 1 1 1 Abhydrolase domain containing 18 Abhydrolase_6 PF12697.7 OQR91805.1 - 6.8e-05 23.6 0.3 0.00016 22.4 0.3 1.5 2 0 0 2 2 2 1 Alpha/beta hydrolase family Esterase PF00756.20 OQR91805.1 - 0.00031 20.5 0.0 0.00048 19.8 0.0 1.3 1 0 0 1 1 1 1 Putative esterase Abhydrolase_1 PF00561.20 OQR91805.1 - 0.00056 19.6 0.1 0.0028 17.4 0.0 2.0 2 0 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 OQR91805.1 - 0.0016 17.7 0.1 0.0094 15.2 0.1 2.0 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Scramblase PF03803.15 OQR91805.1 - 0.068 12.5 0.1 0.11 11.8 0.1 1.3 1 0 0 1 1 1 0 Scramblase Ank_2 PF12796.7 OQR91806.1 - 1.8e-18 66.9 6.5 1.1e-08 35.6 0.2 4.1 3 2 0 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQR91806.1 - 5.9e-18 65.0 6.6 1e-06 29.1 0.2 6.0 4 2 2 6 6 6 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 OQR91806.1 - 1.5e-17 63.4 1.9 0.0002 21.6 0.1 4.8 3 1 1 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQR91806.1 - 1.2e-11 43.7 7.5 0.2 12.3 0.0 7.8 9 0 0 9 9 9 4 Ankyrin repeat Ank PF00023.30 OQR91806.1 - 2.3e-06 27.8 3.0 0.17 12.4 0.0 5.8 5 1 1 6 6 6 1 Ankyrin repeat EF-hand_6 PF13405.6 OQR91807.1 - 4.9e-10 38.5 0.6 1.6e-05 24.5 0.0 4.2 4 0 0 4 4 4 2 EF-hand domain EF-hand_1 PF00036.32 OQR91807.1 - 4.8e-09 35.1 2.8 2.5e-05 23.5 0.1 4.7 5 0 0 5 5 5 2 EF hand EF-hand_7 PF13499.6 OQR91807.1 - 6.4e-07 29.7 1.6 0.0038 17.7 0.0 4.4 5 0 0 5 5 5 1 EF-hand domain pair EF-hand_8 PF13833.6 OQR91807.1 - 2e-06 27.6 1.5 0.00032 20.5 0.1 4.0 4 1 0 4 4 4 1 EF-hand domain pair EF-hand_5 PF13202.6 OQR91807.1 - 0.0022 17.4 0.2 0.0022 17.4 0.2 2.6 4 0 0 4 4 4 1 EF hand HSP70 PF00012.20 OQR91830.1 - 2e-131 439.1 7.0 2.9e-131 438.6 7.0 1.2 1 0 0 1 1 1 1 Hsp70 protein DUF2451 PF10474.9 OQR91830.1 - 1.3e-47 162.6 2.3 3.5e-47 161.2 2.3 1.7 1 0 0 1 1 1 1 Protein of unknown function C-terminus (DUF2451) MreB_Mbl PF06723.13 OQR91830.1 - 2.2e-13 49.7 2.8 4.5e-13 48.7 2.8 1.4 1 0 0 1 1 1 1 MreB/Mbl protein Vps54_N PF10475.9 OQR91830.1 - 5.3e-05 22.7 6.1 5.9e-05 22.5 1.2 3.5 3 1 0 3 3 3 1 Vacuolar-sorting protein 54, of GARP complex PilM_2 PF11104.8 OQR91830.1 - 0.015 14.4 0.1 0.77 8.7 0.0 2.3 2 0 0 2 2 2 0 Type IV pilus assembly protein PilM; DUF1836 PF08876.11 OQR91830.1 - 0.037 14.1 0.2 0.18 11.8 0.2 2.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1836) MitoNEET_N PF10660.9 OQR91831.1 - 9.7e-15 54.3 0.0 1.3e-14 53.9 0.0 1.2 1 0 0 1 1 1 1 Iron-containing outer mitochondrial membrane protein N-terminus zf-CDGSH PF09360.10 OQR91831.1 - 9e-10 38.6 3.1 1.4e-09 38.0 3.1 1.5 1 1 0 1 1 1 1 Iron-binding zinc finger CDGSH type PH PF00169.29 OQR91832.1 - 1.5e-08 35.1 0.3 3.7e-08 33.8 0.2 1.8 2 0 0 2 2 2 1 PH domain PH_4 PF15404.6 OQR91832.1 - 0.017 14.9 0.9 0.73 9.6 0.2 2.3 2 0 0 2 2 2 0 Pleckstrin homology domain DUF2856 PF11043.8 OQR91832.1 - 0.15 12.2 0.1 0.5 10.5 0.1 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2856) RNA_pol_Rpb1_5 PF04998.17 OQR91833.1 - 2.8e-103 345.0 0.1 4.7e-103 344.3 0.1 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_1 PF04997.12 OQR91833.1 - 1.1e-91 307.4 0.0 2e-91 306.6 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_2 PF00623.20 OQR91833.1 - 1.8e-73 246.2 0.2 8.7e-73 244.0 0.0 2.1 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_6 PF04992.14 OQR91833.1 - 5.4e-60 202.5 0.0 1.2e-59 201.4 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 6 RNA_pol_Rpb1_7 PF04990.12 OQR91833.1 - 1.4e-50 170.7 2.4 2.7e-50 169.8 2.4 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 7 RNA_pol_Rpb1_3 PF04983.18 OQR91833.1 - 2.8e-44 150.8 0.0 8.9e-43 145.9 0.0 2.9 3 0 0 3 3 3 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_R PF05001.13 OQR91833.1 - 4.2e-44 146.6 348.5 0.0077 16.5 12.7 19.8 2 2 32 34 34 34 33 RNA polymerase Rpb1 C-terminal repeat RNA_pol_Rpb1_4 PF05000.17 OQR91833.1 - 6.2e-34 116.2 0.1 1.4e-33 115.1 0.1 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 Ferric_reduct PF01794.19 OQR91852.1 - 3.4e-17 62.7 9.3 3.4e-17 62.7 9.3 2.0 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 OQR91852.1 - 1.3e-13 51.4 0.0 2.4e-11 44.0 0.0 2.4 1 1 0 1 1 1 1 Ferric reductase NAD binding domain DOMON PF03351.17 OQR91852.1 - 2.4e-12 47.2 0.8 4e-12 46.4 0.1 1.7 2 0 0 2 2 2 1 DOMON domain FAD_binding_8 PF08022.12 OQR91852.1 - 1.7e-09 37.7 0.0 3.2e-09 36.8 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_1 PF00175.21 OQR91852.1 - 5.7e-07 30.2 0.0 1.2e-06 29.1 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain DUF4405 PF14358.6 OQR91852.1 - 2.6 8.6 16.8 0.036 14.6 2.5 3.6 3 1 0 3 3 3 0 Domain of unknown function (DUF4405) FAD_binding_4 PF01565.23 OQR91853.1 - 4.2e-43 146.4 0.9 1.1e-20 73.7 0.0 2.5 2 0 0 2 2 2 2 FAD binding domain BBE PF08031.12 OQR91853.1 - 1.2e-05 25.3 0.1 4.1e-05 23.6 0.0 1.9 2 0 0 2 2 2 1 Berberine and berberine like ERG2_Sigma1R PF04622.12 OQR91853.1 - 0.00036 19.9 0.2 0.44 9.9 0.0 2.5 2 0 0 2 2 2 2 ERG2 and Sigma1 receptor like protein DUF4381 PF14316.6 OQR91853.1 - 0.092 13.0 0.3 1.6 9.0 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) DUF2934 PF11154.8 OQR91853.1 - 0.11 12.2 0.5 1.1 9.0 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2934) DEAD PF00270.29 OQR91855.1 - 2e-41 141.7 0.0 1.3e-40 139.0 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OQR91855.1 - 1e-21 77.3 0.0 2.2e-21 76.3 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 OQR91855.1 - 0.0032 17.5 0.0 0.0056 16.7 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 OQR91855.1 - 0.011 15.1 0.2 0.11 11.8 0.0 2.0 2 0 0 2 2 2 0 U3-containing 90S pre-ribosomal complex subunit Exosortase_EpsH PF09721.10 OQR91855.1 - 0.069 12.7 0.3 0.12 11.9 0.3 1.3 1 0 0 1 1 1 0 Transmembrane exosortase (Exosortase_EpsH) ACT_3 PF10000.9 OQR91855.1 - 0.11 12.4 0.0 0.26 11.2 0.0 1.6 1 0 0 1 1 1 0 ACT domain AAA_19 PF13245.6 OQR91855.1 - 0.12 12.7 0.0 0.52 10.6 0.0 2.2 2 1 0 2 2 2 0 AAA domain Ank_2 PF12796.7 OQR91857.1 - 3.5e-11 43.5 0.1 9.7e-11 42.1 0.1 1.6 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQR91857.1 - 9.6e-10 38.8 0.1 3.5e-06 27.5 0.0 2.1 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 OQR91857.1 - 4e-09 36.6 0.2 0.049 14.0 0.0 3.0 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQR91857.1 - 1.8e-06 27.8 0.1 0.75 10.6 0.0 3.1 2 1 1 3 3 3 3 Ankyrin repeat Ank PF00023.30 OQR91857.1 - 0.0025 18.2 0.0 14 6.3 0.0 3.1 2 1 0 2 2 2 2 Ankyrin repeat DUF5049 PF16468.5 OQR91857.1 - 0.0025 17.7 0.6 2.3 8.2 0.0 2.9 1 1 2 3 3 3 2 Domain of unknown function (DUF5049) DUF3447 PF11929.8 OQR91857.1 - 0.023 14.7 0.2 0.44 10.5 0.1 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF3447) Ndc80_HEC PF03801.13 OQR91858.1 - 7.8e-42 142.5 0.2 4.6e-41 140.0 0.0 2.4 2 0 0 2 2 2 1 HEC/Ndc80p family DUF641 PF04859.12 OQR91858.1 - 0.0034 17.7 2.1 0.0034 17.7 2.1 4.6 2 2 3 5 5 5 1 Plant protein of unknown function (DUF641) DUF4413 PF14372.6 OQR91858.1 - 0.065 13.6 2.3 8.9 6.8 0.0 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4413) ADH_N PF08240.12 OQR91859.1 - 5.2e-24 84.2 6.6 1e-23 83.3 6.6 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 OQR91859.1 - 3.5e-18 65.8 0.0 6.1e-18 65.0 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 OQR91859.1 - 8.4e-07 30.1 0.0 1.4e-06 29.4 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 OQR91859.1 - 2.8e-05 23.5 0.2 5.2e-05 22.6 0.2 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 OQR91859.1 - 0.0011 18.4 0.1 0.0017 17.7 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Cyt_bd_oxida_I PF01654.17 OQR91859.1 - 0.0084 14.8 0.3 0.014 14.0 0.3 1.3 1 0 0 1 1 1 1 Cytochrome bd terminal oxidase subunit I GFO_IDH_MocA PF01408.22 OQR91859.1 - 0.069 14.0 0.3 0.14 13.0 0.0 1.6 2 0 0 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_7 PF13241.6 OQR91859.1 - 0.12 12.8 0.0 0.26 11.7 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding SHMT PF00464.19 OQR91896.1 - 6.6e-200 663.8 0.0 7.8e-200 663.6 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Aminotran_1_2 PF00155.21 OQR91896.1 - 2.1e-06 27.2 0.0 4.3e-06 26.2 0.0 1.5 1 1 0 1 1 1 1 Aminotransferase class I and II mCpol PF18182.1 OQR91896.1 - 0.009 16.3 0.2 0.02 15.2 0.2 1.5 1 0 0 1 1 1 1 minimal CRISPR polymerase domain Aminotran_5 PF00266.19 OQR91896.1 - 0.035 13.1 0.0 0.052 12.5 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class-V TPR_19 PF14559.6 OQR91897.1 - 7.3e-06 26.4 0.2 1.8e-05 25.2 0.2 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_14 PF13428.6 OQR91897.1 - 0.00011 22.7 2.0 0.056 14.3 0.0 3.8 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 OQR91897.1 - 0.0015 18.8 2.8 0.058 13.7 0.2 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 OQR91897.1 - 0.0036 17.3 0.8 0.011 15.8 0.1 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 OQR91897.1 - 0.0047 17.5 0.0 0.011 16.3 0.0 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_17 PF13431.6 OQR91897.1 - 0.016 15.6 0.4 0.048 14.1 0.1 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat Spond_N PF06468.13 OQR91897.1 - 0.044 13.9 0.0 0.079 13.1 0.0 1.4 1 0 0 1 1 1 0 Spondin_N TPR_4 PF07721.14 OQR91897.1 - 0.045 14.4 0.9 0.16 12.6 0.1 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_20 PF14561.6 OQR91897.1 - 0.05 13.9 0.0 0.11 12.8 0.0 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_6 PF13174.6 OQR91897.1 - 0.067 13.9 0.6 6.7 7.6 0.1 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.6 OQR91897.1 - 0.11 12.6 2.4 0.14 12.3 0.3 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_15 PF13429.6 OQR91897.1 - 0.12 11.6 0.1 0.21 10.8 0.1 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat Homeodomain PF00046.29 OQR91898.1 - 1.8e-25 88.5 6.3 5.1e-09 35.9 0.6 4.2 3 0 0 3 3 3 3 Homeodomain PHD PF00628.29 OQR91898.1 - 3.4e-07 30.0 8.0 6.2e-07 29.2 8.0 1.4 1 0 0 1 1 1 1 PHD-finger zf-4CXXC_R1 PF10497.9 OQR91898.1 - 0.00069 19.8 6.5 0.0015 18.7 6.5 1.5 1 0 0 1 1 1 1 Zinc-finger domain of monoamine-oxidase A repressor R1 Homeobox_KN PF05920.11 OQR91898.1 - 0.0045 16.9 1.9 1.2 9.1 0.2 3.6 3 0 0 3 3 3 1 Homeobox KN domain PHD_4 PF16866.5 OQR91898.1 - 0.0047 17.0 6.9 0.022 14.8 6.9 2.3 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 OQR91898.1 - 0.0054 16.3 1.7 0.013 15.0 1.7 1.6 1 0 0 1 1 1 1 PHD-finger Zf_RING PF16744.5 OQR91898.1 - 0.017 15.2 6.7 0.055 13.6 6.7 1.9 1 0 0 1 1 1 0 KIAA1045 RING finger zf-RING_2 PF13639.6 OQR91898.1 - 0.022 15.1 8.6 0.038 14.3 8.6 1.4 1 0 0 1 1 1 0 Ring finger domain zf-HC5HC2H PF13771.6 OQR91898.1 - 0.041 14.1 7.1 0.12 12.6 7.1 1.8 1 0 0 1 1 1 0 PHD-like zinc-binding domain C1_2 PF03107.16 OQR91898.1 - 0.062 13.6 1.5 0.13 12.6 1.5 1.6 1 0 0 1 1 1 0 C1 domain Prok-RING_1 PF14446.6 OQR91898.1 - 0.09 12.7 7.9 0.2 11.6 7.9 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 TusA PF01206.17 OQR91898.1 - 0.1 12.5 0.1 0.45 10.4 0.1 2.2 1 0 0 1 1 1 0 Sulfurtransferase TusA zf-RING_9 PF13901.6 OQR91898.1 - 0.14 12.1 12.1 0.15 12.0 8.8 2.4 2 0 0 2 2 2 0 Putative zinc-RING and/or ribbon C1_1 PF00130.22 OQR91898.1 - 0.28 11.1 8.8 0.071 13.0 5.6 1.6 1 1 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-RING-like PF08746.11 OQR91898.1 - 4 7.8 10.0 7.2 7.0 10.0 1.4 1 0 0 1 1 1 0 RING-like domain SHMT PF00464.19 OQR91899.1 - 0.019 13.6 0.1 0.021 13.4 0.1 1.2 1 0 0 1 1 1 0 Serine hydroxymethyltransferase MatE PF01554.18 OQR91900.1 - 6.8e-42 142.9 34.5 2e-22 79.6 8.4 2.8 3 0 0 3 3 3 2 MatE Polysacc_synt_C PF14667.6 OQR91900.1 - 7.3e-05 22.9 8.1 7.3e-05 22.9 8.1 4.4 2 2 2 4 4 4 2 Polysaccharide biosynthesis C-terminal domain WD40 PF00400.32 OQR91905.1 - 3.8e-15 56.0 32.6 0.0021 18.9 0.1 11.1 12 0 0 12 12 12 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OQR91905.1 - 8.8e-11 42.0 1.0 0.52 10.7 0.0 7.7 5 4 3 8 8 8 3 Anaphase-promoting complex subunit 4 WD40 domain EF-hand_7 PF13499.6 OQR91905.1 - 6.4e-07 29.7 0.3 1.5e-06 28.5 0.3 1.7 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.6 OQR91905.1 - 1.3e-06 28.1 0.2 3.4e-06 26.8 0.2 1.7 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.6 OQR91905.1 - 2.5e-05 23.5 0.1 6.4e-05 22.3 0.1 1.7 1 0 0 1 1 1 1 EF hand EF-hand_1 PF00036.32 OQR91905.1 - 0.00081 18.8 0.1 0.0026 17.2 0.1 1.9 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 OQR91905.1 - 0.015 15.2 0.1 0.06 13.3 0.1 2.1 1 0 0 1 1 1 0 EF-hand domain Glu_cyclase_2 PF05096.12 OQR91905.1 - 0.068 12.6 0.0 0.13 11.6 0.0 1.4 1 0 0 1 1 1 0 Glutamine cyclotransferase DAGK_cat PF00781.24 OQR91906.1 - 3.8e-25 87.9 0.0 6.6e-25 87.2 0.0 1.4 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain NAD_kinase PF01513.21 OQR91906.1 - 0.18 10.9 0.0 0.32 10.1 0.0 1.3 1 0 0 1 1 1 0 ATP-NAD kinase Pyr_redox_2 PF07992.14 OQR91907.1 - 4.9e-59 200.0 6.9 1.8e-29 102.9 0.1 2.7 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 OQR91907.1 - 7.8e-26 90.5 0.2 2e-25 89.2 0.2 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Epimerase PF01370.21 OQR91907.1 - 6.5e-13 48.7 0.0 1.3e-12 47.7 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Pyr_redox PF00070.27 OQR91907.1 - 5.2e-12 46.1 8.3 5.6e-10 39.6 0.0 3.3 3 0 0 3 3 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 OQR91907.1 - 6.5e-10 38.9 1.0 6.5e-10 38.9 1.0 2.2 3 0 0 3 3 3 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 OQR91907.1 - 2.3e-09 36.8 5.2 1.2e-05 24.6 2.3 3.5 4 0 0 4 4 4 2 FAD binding domain RmlD_sub_bind PF04321.17 OQR91907.1 - 7.2e-09 35.2 0.0 2.1e-08 33.6 0.0 1.7 2 0 0 2 2 2 1 RmlD substrate binding domain GIDA PF01134.22 OQR91907.1 - 9.5e-09 34.8 0.9 1.5e-08 34.2 0.3 1.6 2 0 0 2 2 2 1 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 OQR91907.1 - 2.1e-07 30.5 4.2 0.00074 18.9 0.0 3.3 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 OQR91907.1 - 2.2e-05 23.3 3.6 0.0092 14.7 0.8 3.0 3 0 0 3 3 3 2 HI0933-like protein K_oxygenase PF13434.6 OQR91907.1 - 2.4e-05 23.6 0.7 0.13 11.3 0.0 2.9 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) FAD_binding_3 PF01494.19 OQR91907.1 - 0.00028 20.2 3.7 0.17 11.1 0.1 2.3 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 OQR91907.1 - 0.00034 20.8 1.4 0.0011 19.2 0.9 2.2 3 0 0 3 3 1 1 NAD(P)-binding Rossmann-like domain GDP_Man_Dehyd PF16363.5 OQR91907.1 - 0.00046 19.7 0.0 0.007 15.8 0.0 2.2 1 1 1 2 2 2 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 OQR91907.1 - 0.001 18.2 0.0 0.0035 16.5 0.0 1.8 1 1 1 2 2 2 1 Polysaccharide biosynthesis protein Thi4 PF01946.17 OQR91907.1 - 0.0016 17.8 0.0 0.0029 16.9 0.0 1.4 1 0 0 1 1 1 1 Thi4 family DXP_reductoisom PF02670.16 OQR91907.1 - 0.0019 18.9 0.0 0.0087 16.8 0.0 2.2 2 0 0 2 2 1 1 1-deoxy-D-xylulose 5-phosphate reductoisomerase DAO PF01266.24 OQR91907.1 - 0.019 14.6 0.9 5.2 6.5 0.3 2.7 3 0 0 3 3 3 0 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 OQR91907.1 - 0.02 14.0 0.1 1.3 8.0 0.0 2.3 2 0 0 2 2 2 0 Lycopene cyclase protein Lipase_3 PF01764.25 OQR91907.1 - 0.036 13.9 0.1 0.087 12.7 0.1 1.6 1 0 0 1 1 1 0 Lipase (class 3) 3Beta_HSD PF01073.19 OQR91907.1 - 0.042 12.8 0.1 0.9 8.5 0.0 2.3 1 1 1 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family GlcNAc PF11397.8 OQR91915.1 - 3e-57 194.7 1.3 8.9e-47 160.2 1.9 2.5 1 1 1 2 2 2 2 Glycosyltransferase (GlcNAc) PI_PP_I PF18363.1 OQR91915.1 - 0.047 13.9 1.2 0.19 11.9 0.4 2.2 2 0 0 2 2 2 0 Phosphoinositide phosphatase insertion domain APG6_N PF17675.1 OQR91915.1 - 0.089 13.3 6.4 0.16 12.5 6.4 1.4 1 0 0 1 1 1 0 Apg6 coiled-coil region VERL PF11386.8 OQR91916.1 - 0.05 13.8 0.0 0.11 12.7 0.0 1.6 1 0 0 1 1 1 0 Vitelline envelope receptor for lysin PP2C PF00481.21 OQR91918.1 - 1.2e-48 166.0 0.0 1.6e-46 159.0 0.0 2.2 1 1 1 2 2 2 2 Protein phosphatase 2C Toprim_Crpt PF13342.6 OQR91918.1 - 0.005 16.8 0.1 0.012 15.5 0.1 1.6 1 0 0 1 1 1 1 C-terminal repeat of topoisomerase DUF1043 PF06295.12 OQR91918.1 - 0.18 11.8 1.5 0.47 10.5 1.5 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) GHMP_kinases_N PF00288.26 OQR91919.1 - 3.6e-13 49.5 3.0 5.7e-13 48.9 1.3 2.3 2 0 0 2 2 2 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 OQR91919.1 - 2.2e-06 28.0 0.0 5e-06 26.8 0.0 1.6 1 0 0 1 1 1 1 GHMP kinases C terminal SoPB_HTH PF18090.1 OQR91919.1 - 0.027 14.6 0.0 0.49 10.6 0.0 2.5 2 0 0 2 2 2 0 Centromere-binding protein HTH domain EFP_N PF08207.12 OQR91920.1 - 1.2e-19 70.1 0.0 2.5e-19 69.1 0.0 1.6 1 0 0 1 1 1 1 Elongation factor P (EF-P) KOW-like domain EFP PF01132.20 OQR91920.1 - 6.1e-14 51.8 0.3 9.8e-14 51.1 0.3 1.3 1 0 0 1 1 1 1 Elongation factor P (EF-P) OB domain Elong-fact-P_C PF09285.11 OQR91920.1 - 2.6e-08 33.5 1.6 3.1e-08 33.2 0.4 1.8 2 0 0 2 2 2 1 Elongation factor P, C-terminal Ribosomal_S4e PF00900.20 OQR91920.1 - 0.00051 19.9 0.1 0.0085 16.0 0.0 2.3 2 0 0 2 2 2 1 Ribosomal family S4e Geminin PF07412.12 OQR91931.1 - 2.9e-06 27.2 46.7 0.088 12.5 3.3 7.2 7 0 0 7 7 7 5 Geminin TFIID-18kDa PF02269.16 OQR91931.1 - 0.022 14.8 0.8 16 5.6 0.0 4.2 4 0 0 4 4 4 0 Transcription initiation factor IID, 18kD subunit YxiJ PF14176.6 OQR91931.1 - 0.074 13.5 0.1 34 5.0 0.0 4.3 4 0 0 4 4 4 0 YxiJ-like protein HrpB2 PF09487.10 OQR91931.1 - 1.4 9.4 3.9 30 5.1 0.3 3.7 3 0 0 3 3 3 0 Bacterial type III secretion protein (HrpB2) PIN_6 PF17146.4 OQR91931.1 - 2 9.0 4.7 19 5.8 0.3 3.2 2 0 0 2 2 2 0 PIN domain of ribonuclease Arm PF00514.23 OQR91933.1 - 0.11 12.5 0.0 0.11 12.5 0.0 7.6 9 0 0 9 9 9 0 Armadillo/beta-catenin-like repeat API5 PF05918.11 OQR91933.1 - 1.4 7.6 6.6 1.2 7.8 0.2 2.8 3 0 0 3 3 3 0 Apoptosis inhibitory protein 5 (API5) Methyltransf_16 PF10294.9 OQR91959.1 - 2.4e-17 63.2 0.0 4.4e-17 62.4 0.0 1.4 1 1 0 1 1 1 1 Lysine methyltransferase PrmA PF06325.13 OQR91959.1 - 3.3e-13 49.7 0.1 5.1e-13 49.1 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 OQR91959.1 - 4.4e-07 29.6 1.0 4.9e-07 29.4 0.1 1.5 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_25 PF13649.6 OQR91959.1 - 8.1e-06 26.5 0.0 1.3e-05 25.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OQR91959.1 - 0.00013 22.7 0.1 0.00024 21.8 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.15 OQR91959.1 - 0.00054 19.6 0.0 0.00067 19.4 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Met_10 PF02475.16 OQR91959.1 - 0.002 17.9 0.0 0.0028 17.4 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_23 PF13489.6 OQR91959.1 - 0.0028 17.5 0.0 0.0032 17.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OQR91959.1 - 0.0031 17.3 0.1 0.0051 16.6 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OQR91959.1 - 0.0065 17.1 0.0 0.01 16.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain tRNA_U5-meth_tr PF05958.11 OQR91959.1 - 0.0069 15.4 0.1 0.009 15.0 0.1 1.1 1 0 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase CMAS PF02353.20 OQR91959.1 - 0.091 12.0 0.0 0.12 11.6 0.0 1.1 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Complex1_LYR PF05347.15 OQR91960.1 - 1.5e-09 37.7 0.1 2.2e-09 37.2 0.1 1.3 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Spot_14 PF07084.12 OQR91960.1 - 0.05 13.7 0.3 0.05 13.7 0.3 1.1 1 0 0 1 1 1 0 Thyroid hormone-inducible hepatic protein Spot 14 AA_permease_2 PF13520.6 OQR91961.1 - 1e-41 143.2 38.2 1e-41 143.2 38.2 2.1 1 1 2 3 3 3 1 Amino acid permease AA_permease PF00324.21 OQR91961.1 - 6.9e-26 90.9 44.0 6.9e-26 90.9 44.0 1.8 2 1 0 2 2 2 1 Amino acid permease AA_permease_C PF13906.6 OQR91961.1 - 6.8e-18 64.5 8.8 6.8e-18 64.5 8.8 4.1 4 0 0 4 4 4 1 C-terminus of AA_permease Spore_permease PF03845.13 OQR91961.1 - 3.4e-05 22.9 14.7 3.4e-05 22.9 14.7 3.0 2 1 0 3 3 3 1 Spore germination protein DUF1516 PF07457.11 OQR91961.1 - 0.27 11.5 0.0 0.27 11.5 0.0 3.9 4 0 0 4 4 4 0 Protein of unknown function (DUF1516) CSRNP_N PF16019.5 OQR91962.1 - 5.6e-07 29.7 1.5 1e-06 28.8 1.5 1.5 1 1 0 1 1 1 1 Cysteine/serine-rich nuclear protein N-terminus RMI1_N PF08585.12 OQR91962.1 - 0.0088 15.8 0.7 0.0094 15.7 0.7 1.1 1 0 0 1 1 1 1 RecQ mediated genome instability protein GatB_N PF02934.15 OQR91963.1 - 1.4e-108 362.5 1.0 1.7e-108 362.2 1.0 1.1 1 0 0 1 1 1 1 GatB/GatE catalytic domain GatB_Yqey PF02637.18 OQR91963.1 - 2.4e-38 131.3 0.0 5.2e-38 130.2 0.0 1.6 1 0 0 1 1 1 1 GatB domain Collectrin PF16959.5 OQR91963.1 - 0.074 12.8 0.3 0.22 11.3 0.3 1.7 2 0 0 2 2 2 0 Renal amino acid transporter Cyclin_C PF02984.19 OQR91965.1 - 6.9e-20 71.3 2.6 7.6e-20 71.2 2.6 1.0 1 0 0 1 1 1 1 Cyclin, C-terminal domain Exo_endo_phos_2 PF14529.6 OQR91966.1 - 0.085 12.7 0.3 0.42 10.5 0.2 1.9 1 1 1 2 2 2 0 Endonuclease-reverse transcriptase PK PF00224.21 OQR91967.1 - 8.2e-109 363.7 2.7 1.3e-108 363.0 2.7 1.2 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.16 OQR91967.1 - 2.4e-21 76.1 0.0 4.3e-20 72.1 0.0 2.6 2 1 0 2 2 2 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.14 OQR91967.1 - 5.3e-05 22.5 1.1 0.00023 20.4 0.1 2.1 2 0 0 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family ChlamPMP_M PF07548.11 OQR91967.1 - 0.15 12.0 0.0 0.27 11.2 0.0 1.4 1 0 0 1 1 1 0 Chlamydia polymorphic membrane protein middle domain FYVE PF01363.21 OQR91968.1 - 8e-07 29.1 3.9 1.5e-06 28.2 3.9 1.5 1 0 0 1 1 1 1 FYVE zinc finger GAF PF01590.26 OQR91968.1 - 0.018 15.7 0.0 0.046 14.3 0.0 1.7 1 0 0 1 1 1 0 GAF domain zf-C3HC4_3 PF13920.6 OQR91968.1 - 0.063 13.1 13.3 0.14 12.1 13.3 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_1 PF14446.6 OQR91968.1 - 0.16 11.9 8.0 0.28 11.1 8.0 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 DUF1451 PF07295.11 OQR91968.1 - 0.93 9.5 6.7 18 5.3 7.4 2.3 2 0 0 2 2 2 0 Zinc-ribbon containing domain FYVE_2 PF02318.16 OQR91968.1 - 1.1 9.5 9.9 1.9 8.7 9.9 1.4 1 0 0 1 1 1 0 FYVE-type zinc finger zf-B_box PF00643.24 OQR91968.1 - 1.7 8.9 10.1 4.7 7.4 10.1 1.8 1 1 0 1 1 1 0 B-box zinc finger Ank_2 PF12796.7 OQR91972.1 - 4.9e-30 103.9 1.6 4.2e-10 40.1 0.1 3.7 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQR91972.1 - 1.7e-29 101.8 2.5 5.2e-09 36.5 0.1 4.7 2 1 3 5 5 5 4 Ankyrin repeats (many copies) Ank PF00023.30 OQR91972.1 - 1.6e-26 91.5 1.1 1.2e-05 25.6 0.0 6.2 6 0 0 6 6 6 4 Ankyrin repeat Ank_5 PF13857.6 OQR91972.1 - 9.5e-24 83.2 0.1 1.2e-06 28.7 0.0 4.8 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQR91972.1 - 1.9e-22 76.9 0.8 5.9e-05 23.2 0.0 6.5 7 0 0 7 7 7 4 Ankyrin repeat LRR_6 PF13516.6 OQR91973.1 - 4e-16 57.6 23.5 0.0046 16.9 0.3 9.5 11 0 0 11 11 11 6 Leucine Rich repeat IMS PF00817.20 OQR91975.1 - 1.3e-43 148.6 0.0 2.3e-43 147.8 0.0 1.4 1 0 0 1 1 1 1 impB/mucB/samB family IMS_HHH PF11798.8 OQR91975.1 - 0.044 14.1 0.0 0.15 12.5 0.0 1.9 1 0 0 1 1 1 0 IMS family HHH motif EbsA PF17255.2 OQR91975.1 - 0.33 11.3 5.7 0.23 11.8 3.5 1.9 2 0 0 2 2 2 0 EbsA-like protein Glyco_hydro_47 PF01532.20 OQR91976.1 - 1.3e-138 462.8 0.1 1.5e-138 462.6 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 DUF455 PF04305.14 OQR91990.1 - 3.5e-80 269.1 0.1 4e-80 268.9 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF455) DUF1192 PF06698.11 OQR91991.1 - 0.44 10.6 5.9 2.6 8.1 0.1 3.9 3 1 0 3 3 3 0 Protein of unknown function (DUF1192) Cupin_8 PF13621.6 OQR91992.1 - 8.2e-21 74.9 6.5 9.1e-20 71.4 0.1 3.6 3 1 0 3 3 3 1 Cupin-like domain JmjC PF02373.22 OQR91992.1 - 6.1e-14 52.4 5.9 1.6e-12 47.9 0.1 4.5 4 1 0 4 4 4 1 JmjC domain, hydroxylase F-box-like PF12937.7 OQR91992.1 - 1.1e-05 25.2 0.5 2.5e-05 24.1 0.5 1.6 1 0 0 1 1 1 1 F-box-like Cupin_4 PF08007.12 OQR91992.1 - 0.0017 17.9 0.2 0.0046 16.5 0.0 1.8 2 0 0 2 2 2 1 Cupin superfamily protein F-box PF00646.33 OQR91992.1 - 0.0096 15.8 0.0 0.023 14.6 0.0 1.6 1 0 0 1 1 1 1 F-box domain SR-25 PF10500.9 OQR91992.1 - 0.018 14.7 8.0 0.029 14.0 8.0 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Cupin_1 PF00190.22 OQR91992.1 - 0.043 13.4 0.0 0.076 12.6 0.0 1.3 1 0 0 1 1 1 0 Cupin DUF1738 PF08401.11 OQR91992.1 - 0.063 13.4 2.5 0.2 11.7 2.5 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF1738) GAGA_bind PF06217.12 OQR91992.1 - 0.088 13.1 4.1 0.14 12.4 4.1 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family Med19 PF10278.9 OQR91992.1 - 0.52 10.2 12.0 0.9 9.4 12.0 1.3 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 ketoacyl-synt PF00109.26 OQR91993.1 - 1.2e-12 48.0 2.2 1.2e-12 48.0 2.2 2.3 2 1 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.10 OQR91993.1 - 9.6e-10 38.2 0.6 4.5e-07 29.6 0.1 2.5 2 0 0 2 2 2 2 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Inhibitor_I29 PF08246.12 OQR91995.1 - 8 7.0 8.8 1.4 9.4 0.3 3.2 3 0 0 3 3 3 0 Cathepsin propeptide inhibitor domain (I29) Leg1 PF05612.12 OQR91996.1 - 0.0053 16.0 0.1 0.0082 15.3 0.1 1.2 1 0 0 1 1 1 1 Leg1 FMO-like PF00743.19 OQR91996.1 - 0.035 12.5 0.1 0.079 11.4 0.1 1.5 1 0 0 1 1 1 0 Flavin-binding monooxygenase-like Tropomyosin_1 PF12718.7 OQR91997.1 - 0.00032 20.9 10.1 0.00032 20.9 10.1 5.3 3 1 1 5 5 5 1 Tropomyosin like XhlA PF10779.9 OQR91997.1 - 0.0037 17.4 4.2 0.0037 17.4 4.2 2.9 2 1 2 4 4 4 1 Haemolysin XhlA Prefoldin_2 PF01920.20 OQR91997.1 - 0.02 14.8 5.1 0.02 14.8 5.1 4.9 3 2 3 6 6 6 0 Prefoldin subunit FlaC_arch PF05377.11 OQR91997.1 - 0.9 10.0 8.0 3.8 8.0 2.8 3.7 2 2 2 4 4 4 0 Flagella accessory protein C (FlaC) SecD-TM1 PF13721.6 OQR91997.1 - 9.3 6.8 11.2 6.5 7.3 1.7 3.5 3 0 0 3 3 3 0 SecD export protein N-terminal TM region adh_short_C2 PF13561.6 OQR91998.1 - 2e-52 178.1 0.0 2.6e-52 177.7 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OQR91998.1 - 9.8e-50 168.7 0.0 1.2e-49 168.4 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OQR91998.1 - 3.3e-08 33.7 0.0 4.1e-08 33.3 0.0 1.2 1 0 0 1 1 1 1 KR domain FTR PF01913.18 OQR91998.1 - 0.031 14.2 0.0 0.054 13.5 0.0 1.4 1 0 0 1 1 1 0 Formylmethanofuran-tetrahydromethanopterin formyltransferase Epimerase PF01370.21 OQR91998.1 - 0.17 11.3 0.0 0.45 9.9 0.0 1.8 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Lactamase_B_2 PF12706.7 OQR92010.1 - 0.00028 20.5 0.0 0.0025 17.4 0.0 2.2 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 OQR92010.1 - 0.0003 20.9 0.0 0.00057 20.0 0.0 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily 4HB_MCP_1 PF12729.7 OQR92010.1 - 0.012 15.1 3.8 0.017 14.7 0.5 2.5 2 0 0 2 2 2 0 Four helix bundle sensory module for signal transduction Asp_Arg_Hydrox PF05118.15 OQR92011.1 - 7.1e-31 107.2 0.2 7.1e-30 103.9 0.0 2.2 2 0 0 2 2 2 1 Aspartyl/Asparaginyl beta-hydroxylase Methyltransf_31 PF13847.6 OQR92011.1 - 7.7e-12 45.3 0.2 1.5e-11 44.3 0.2 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OQR92011.1 - 1.3e-08 35.4 0.1 2.6e-08 34.4 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OQR92011.1 - 2e-08 34.3 0.0 3e-08 33.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OQR92011.1 - 2.5e-08 34.5 0.1 5.6e-08 33.4 0.1 1.6 1 0 0 1 1 1 1 Methyltransferase domain MetW PF07021.12 OQR92011.1 - 1.1e-06 28.4 0.1 2e-06 27.5 0.1 1.4 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_12 PF08242.12 OQR92011.1 - 1.1e-06 29.2 0.1 1.1e-06 29.2 0.1 2.0 2 0 0 2 2 2 1 Methyltransferase domain FtsJ PF01728.19 OQR92011.1 - 0.0061 16.7 0.2 0.013 15.7 0.1 1.6 1 1 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_32 PF13679.6 OQR92011.1 - 0.009 16.0 0.0 0.017 15.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 OQR92011.1 - 0.041 13.6 0.1 0.08 12.7 0.1 1.4 1 1 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) PrmA PF06325.13 OQR92011.1 - 0.043 13.2 0.0 0.076 12.4 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 OQR92011.1 - 0.047 13.2 0.0 0.083 12.4 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain TRAPP PF04051.16 OQR92012.1 - 1.2e-39 135.4 0.0 1.3e-39 135.2 0.0 1.0 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component HSP90 PF00183.18 OQR92013.1 - 7.5e-154 513.4 21.5 9.2e-154 513.1 21.5 1.1 1 0 0 1 1 1 1 Hsp90 protein HATPase_c PF02518.26 OQR92013.1 - 2.7e-15 56.9 0.1 6.9e-15 55.5 0.1 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 OQR92013.1 - 2.6e-11 43.5 0.4 9.2e-11 41.7 0.3 2.0 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase CobT PF06213.12 OQR92013.1 - 0.12 11.8 18.2 1.3 8.3 11.0 2.7 3 0 0 3 3 3 0 Cobalamin biosynthesis protein CobT PDCD2_C PF04194.13 OQR92013.1 - 0.23 11.5 12.6 0.063 13.4 5.6 2.3 2 0 0 2 2 2 0 Programmed cell death protein 2, C-terminal putative domain RXT2_N PF08595.11 OQR92013.1 - 0.39 10.7 13.2 0.9 9.6 1.1 2.6 2 0 0 2 2 2 0 RXT2-like, N-terminal RNase_H2_suC PF08615.11 OQR92013.1 - 1.2 9.3 5.6 26 5.0 3.9 2.4 2 0 0 2 2 2 0 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) CDC45 PF02724.14 OQR92013.1 - 1.6 6.9 15.9 1.7 6.8 8.8 2.1 2 0 0 2 2 2 0 CDC45-like protein DUF3381 PF11861.8 OQR92013.1 - 3.6 7.4 20.2 0.19 11.5 9.2 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF3381) ANAPC15 PF15243.6 OQR92013.1 - 4.5 7.7 25.0 3.2 8.2 13.0 2.6 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 15 SDA1 PF05285.12 OQR92013.1 - 8.1 5.8 25.1 5.2 6.4 2.1 2.2 2 0 0 2 2 2 0 SDA1 FAM176 PF14851.6 OQR92013.1 - 9.1 5.9 17.2 6.9 6.3 0.3 2.4 2 0 0 2 2 2 0 FAM176 family Nop25 PF09805.9 OQR92013.1 - 9.5 6.7 20.8 3.1 8.3 2.1 2.5 2 0 0 2 2 2 0 Nucleolar protein 12 (25kDa) DUF4611 PF15387.6 OQR92013.1 - 9.9 6.5 17.0 11 6.3 2.5 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4611) Hexapep PF00132.24 OQR92026.1 - 1.6e-15 56.1 18.0 8e-06 25.4 1.5 4.3 3 1 1 4 4 4 4 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 OQR92026.1 - 4.6e-05 23.1 16.0 0.014 15.1 3.3 3.9 3 1 1 4 4 4 2 Hexapeptide repeat of succinyl-transferase Fucokinase PF07959.12 OQR92026.1 - 0.18 10.7 1.7 0.7 8.8 0.5 1.9 1 1 1 2 2 2 0 L-fucokinase DUF4455 PF14643.6 OQR92027.1 - 1e-59 202.5 23.3 4.7e-38 131.1 11.8 2.9 2 0 0 2 2 2 2 Domain of unknown function (DUF4455) DUF4456 PF14644.6 OQR92027.1 - 1e-41 143.0 1.2 1e-41 143.0 1.2 4.8 5 1 0 5 5 5 2 Domain of unknown function (DUF4456) RNA_pol_Rbc25 PF08292.12 OQR92027.1 - 6.2e-22 78.2 0.1 2.4e-21 76.3 0.1 2.1 1 0 0 1 1 1 1 RNA polymerase III subunit Rpc25 SHS2_Rpb7-N PF03876.17 OQR92027.1 - 1.4e-12 47.8 0.1 4.6e-12 46.1 0.1 2.0 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1 PF00575.23 OQR92027.1 - 0.04 14.3 0.0 0.16 12.3 0.0 2.1 1 0 0 1 1 1 0 S1 RNA binding domain Rhomboid PF01694.22 OQR92028.1 - 6.8e-25 87.8 9.3 6.8e-25 87.8 9.3 1.4 2 0 0 2 2 2 1 Rhomboid family Mesd PF10185.9 OQR92028.1 - 0.14 12.1 0.0 0.21 11.5 0.0 1.2 1 0 0 1 1 1 0 Chaperone for wingless signalling and trafficking of LDL receptor Mito_carr PF00153.27 OQR92029.1 - 1.9e-65 216.8 6.2 2.5e-24 85.0 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein PP2C PF00481.21 OQR92030.1 - 7.6e-55 186.3 0.0 2.4e-54 184.7 0.0 1.9 1 0 0 1 1 1 1 Protein phosphatase 2C Pkinase PF00069.25 OQR92030.1 - 3.1e-16 59.5 0.0 6.5e-16 58.5 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQR92030.1 - 2.7e-05 23.6 0.0 5.2e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase SpoIIE PF07228.12 OQR92030.1 - 0.17 11.8 0.1 0.17 11.8 0.1 2.2 2 0 0 2 2 2 0 Stage II sporulation protein E (SpoIIE) HMG_box PF00505.19 OQR92031.1 - 7.6e-11 42.3 0.4 1.4e-10 41.5 0.0 1.6 2 1 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.10 OQR92031.1 - 5.2e-05 23.7 0.0 0.0001 22.8 0.0 1.5 1 0 0 1 1 1 1 HMG-box domain MATalpha_HMGbox PF04769.12 OQR92031.1 - 0.0026 17.1 0.1 0.0031 16.8 0.1 1.0 1 0 0 1 1 1 1 Mating-type protein MAT alpha 1 HMG-box Myosin_head PF00063.21 OQR92032.1 - 1.1e-30 106.6 0.0 1.3e-30 106.3 0.0 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_N PF02736.19 OQR92032.1 - 0.012 15.4 0.2 0.02 14.7 0.2 1.3 1 0 0 1 1 1 0 Myosin N-terminal SH3-like domain PIP5K PF01504.18 OQR92034.1 - 4.6e-57 193.3 0.6 3e-45 154.6 0.0 2.2 2 0 0 2 2 2 2 Phosphatidylinositol-4-phosphate 5-Kinase IR1-M PF12185.8 OQR92034.1 - 0.088 12.8 0.1 0.23 11.4 0.1 1.7 1 0 0 1 1 1 0 Nup358/RanBP2 E3 ligase domain FAE1_CUT1_RppA PF08392.12 OQR92043.1 - 0.012 14.9 0.1 0.016 14.5 0.1 1.1 1 0 0 1 1 1 0 FAE1/Type III polyketide synthase-like protein Ank_2 PF12796.7 OQR92047.1 - 2.8e-145 473.3 33.7 1.2e-17 64.3 0.1 8.4 1 1 9 11 11 11 11 Ankyrin repeats (3 copies) Ank PF00023.30 OQR92047.1 - 2.3e-100 325.0 37.6 2.9e-09 36.9 0.0 16.1 14 2 2 16 16 16 15 Ankyrin repeat Ank_4 PF13637.6 OQR92047.1 - 1.1e-85 280.9 15.8 3.2e-13 49.9 0.0 12.6 4 3 10 14 14 14 13 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQR92047.1 - 2.5e-78 248.6 14.8 2.1e-06 27.6 0.0 16.0 15 1 1 16 16 16 15 Ankyrin repeat Ank_5 PF13857.6 OQR92047.1 - 1.4e-73 241.9 20.7 5.2e-12 45.8 0.4 11.0 2 2 10 13 13 13 13 Ankyrin repeats (many copies) PEGA PF08308.11 OQR92047.1 - 6.9e-07 29.1 0.5 44 4.1 0.0 8.8 12 0 0 12 12 12 0 PEGA domain DUF3915 PF13054.6 OQR92047.1 - 0.013 15.5 0.3 0.12 12.4 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3915) DUF2384 PF09722.10 OQR92047.1 - 0.023 14.7 0.0 1.8e+02 2.3 0.0 5.4 7 0 0 7 7 7 0 Protein of unknown function (DUF2384) CUE PF02845.16 OQR92047.1 - 0.027 14.2 1.0 12 5.8 0.0 3.9 4 0 0 4 4 4 0 CUE domain DUF2520 PF10728.9 OQR92047.1 - 0.038 13.8 1.5 3.6 7.4 0.3 3.6 3 1 1 4 4 4 0 Domain of unknown function (DUF2520) EPSP_synthase PF00275.20 OQR92047.1 - 0.13 10.9 3.1 30 3.1 0.0 4.7 5 1 0 5 5 5 0 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) ANAPC1 PF12859.7 OQR92050.1 - 2.4e-10 41.1 0.3 2.4e-06 28.1 0.0 3.2 1 1 1 2 2 2 2 Anaphase-promoting complex subunit 1 APC1_C PF18122.1 OQR92050.1 - 0.019 14.9 1.2 0.056 13.4 1.2 1.7 1 0 0 1 1 1 0 Anaphase-promoting complex sub unit 1 C-terminal domain PC_rep PF01851.22 OQR92050.1 - 8.7 7.0 8.7 40 4.9 0.1 4.3 6 0 0 6 6 6 0 Proteasome/cyclosome repeat MFS_1 PF07690.16 OQR92051.1 - 9.9e-28 97.1 34.6 1.1e-26 93.6 34.4 2.2 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 OQR92051.1 - 1.6e-12 47.0 23.4 2.4e-07 30.0 6.9 2.6 2 1 1 3 3 3 2 Sugar (and other) transporter MFS_2 PF13347.6 OQR92051.1 - 0.43 9.1 26.0 0.03 12.9 5.4 3.1 2 1 1 3 3 3 0 MFS/sugar transport protein Oleosin PF01277.17 OQR92051.1 - 1.7 8.4 5.9 9.3 6.1 0.0 3.0 1 1 0 2 2 2 0 Oleosin Lipocalin_3 PF12702.7 OQR92052.1 - 0.062 13.4 0.3 0.11 12.6 0.3 1.5 1 0 0 1 1 1 0 Lipocalin-like TPR_1 PF00515.28 OQR92053.1 - 0.00083 19.1 2.9 0.022 14.6 0.0 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.6 OQR92053.1 - 0.0013 19.0 0.2 0.0013 19.0 0.2 4.0 3 1 2 5 5 5 1 Tetratricopeptide repeat TPR_7 PF13176.6 OQR92053.1 - 0.002 18.0 3.1 0.014 15.4 0.0 3.3 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.6 OQR92053.1 - 0.0031 18.1 2.1 4.7 8.0 0.0 3.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.17 OQR92053.1 - 0.005 16.9 12.5 0.26 11.5 0.0 5.3 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_8 PF13181.6 OQR92053.1 - 0.023 14.9 6.6 1.5 9.2 0.0 4.7 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_14 PF13428.6 OQR92053.1 - 0.039 14.8 9.4 5.4 8.1 0.0 5.1 5 2 2 7 7 7 0 Tetratricopeptide repeat TPR_10 PF13374.6 OQR92053.1 - 0.11 12.4 5.7 0.41 10.6 0.0 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.6 OQR92053.1 - 2.1 9.1 8.6 12 6.8 0.1 4.7 6 0 0 6 6 6 0 Tetratricopeptide repeat TEX13 PF15186.6 OQR92054.1 - 0.00022 21.0 7.2 0.00022 21.0 7.2 2.1 2 0 0 2 2 2 1 Testis-expressed sequence 13 protein family DUF812 PF05667.11 OQR92054.1 - 0.00031 19.8 7.4 0.00046 19.2 7.4 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF812) Spc7 PF08317.11 OQR92054.1 - 0.00031 19.7 5.1 0.00031 19.7 5.1 1.9 2 0 0 2 2 2 1 Spc7 kinetochore protein IFT57 PF10498.9 OQR92054.1 - 0.00046 19.3 5.9 0.00046 19.3 5.9 1.7 2 0 0 2 2 2 1 Intra-flagellar transport protein 57 EzrA PF06160.12 OQR92054.1 - 0.0011 17.2 7.6 0.0018 16.5 7.6 1.3 1 0 0 1 1 1 1 Septation ring formation regulator, EzrA Exonuc_VII_L PF02601.15 OQR92054.1 - 0.0026 17.4 0.7 0.0026 17.4 0.7 2.0 2 0 0 2 2 2 1 Exonuclease VII, large subunit AAA_13 PF13166.6 OQR92054.1 - 0.0043 15.8 1.8 0.0043 15.8 1.8 1.9 2 0 0 2 2 2 1 AAA domain BLOC1S3 PF15753.5 OQR92054.1 - 0.0046 17.1 5.6 0.012 15.7 5.6 1.7 1 0 0 1 1 1 1 Biogenesis of lysosome-related organelles complex 1 subunit 3 Laminin_II PF06009.12 OQR92054.1 - 0.0056 16.7 5.5 0.0056 16.7 5.5 1.8 2 0 0 2 2 1 1 Laminin Domain II Med4 PF10018.9 OQR92054.1 - 0.0057 16.4 6.7 0.0057 16.4 6.7 1.8 2 0 0 2 2 2 1 Vitamin-D-receptor interacting Mediator subunit 4 DUF5082 PF16888.5 OQR92054.1 - 0.0059 16.9 6.1 0.0059 16.9 6.1 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF5082) EMP24_GP25L PF01105.24 OQR92054.1 - 0.01 15.8 4.2 0.48 10.3 4.2 2.2 1 1 0 1 1 1 0 emp24/gp25L/p24 family/GOLD APG6_N PF17675.1 OQR92054.1 - 0.015 15.9 8.2 0.015 15.9 8.2 2.2 2 0 0 2 2 2 0 Apg6 coiled-coil region DUF948 PF06103.11 OQR92054.1 - 0.016 15.5 2.8 0.032 14.5 2.8 1.4 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) AAA_23 PF13476.6 OQR92054.1 - 0.018 15.5 1.2 0.018 15.5 1.2 1.9 2 0 0 2 2 1 0 AAA domain GOLD_2 PF13897.6 OQR92054.1 - 0.019 15.4 5.1 0.062 13.8 0.0 3.2 2 1 2 4 4 3 0 Golgi-dynamics membrane-trafficking Mod_r PF07200.13 OQR92054.1 - 0.019 15.0 7.8 0.019 15.0 7.8 1.9 2 0 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein DUF1664 PF07889.12 OQR92054.1 - 0.023 14.7 5.3 0.023 14.7 5.3 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Cep57_CLD_2 PF14197.6 OQR92054.1 - 0.025 14.6 4.9 0.09 12.9 4.9 2.0 1 0 0 1 1 1 0 Centrosome localisation domain of PPC89 DUF2730 PF10805.8 OQR92054.1 - 0.026 14.6 4.3 0.06 13.4 4.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2730) V_ATPase_I PF01496.19 OQR92054.1 - 0.035 12.0 3.4 0.057 11.4 3.4 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family OmpH PF03938.14 OQR92054.1 - 0.039 14.3 12.2 0.038 14.3 6.1 2.2 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) Atg14 PF10186.9 OQR92054.1 - 0.052 12.6 12.2 0.008 15.3 5.3 2.1 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 XhlA PF10779.9 OQR92054.1 - 0.14 12.3 1.6 0.39 11.0 1.3 1.9 1 1 0 1 1 1 0 Haemolysin XhlA LPP PF04728.13 OQR92054.1 - 0.16 12.4 14.8 1.2 9.6 3.6 3.4 3 0 0 3 3 3 0 Lipoprotein leucine-zipper SlyX PF04102.12 OQR92054.1 - 0.25 12.0 12.6 1.3 9.7 10.6 2.7 1 1 1 2 2 2 0 SlyX Rogdi_lz PF10259.9 OQR92054.1 - 0.29 10.5 8.6 1.8 8.0 7.5 2.0 1 1 1 2 2 2 0 Rogdi leucine zipper containing protein FlaC_arch PF05377.11 OQR92054.1 - 0.47 10.9 5.8 30 5.1 5.3 2.8 1 1 0 1 1 1 0 Flagella accessory protein C (FlaC) Fib_alpha PF08702.10 OQR92054.1 - 0.53 10.5 9.2 0.067 13.4 3.6 2.2 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family GrpE PF01025.19 OQR92054.1 - 0.71 9.5 8.1 0.11 12.2 2.0 2.4 3 0 0 3 3 2 0 GrpE DUF16 PF01519.16 OQR92054.1 - 0.76 10.3 10.2 0.079 13.5 5.6 1.8 2 0 0 2 2 1 0 Protein of unknown function DUF16 Cob_adeno_trans PF01923.18 OQR92054.1 - 0.91 9.6 6.6 0.17 12.0 2.5 1.9 2 0 0 2 2 2 0 Cobalamin adenosyltransferase DUF4795 PF16043.5 OQR92054.1 - 1.1 8.8 10.4 1 8.9 7.2 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4795) T3SSipB PF16535.5 OQR92054.1 - 1.4 9.4 15.5 1.2 9.6 7.5 2.2 2 0 0 2 2 2 0 Type III cell invasion protein SipB Myb_DNA-bind_5 PF13873.6 OQR92054.1 - 2.2 8.4 9.8 6.7 6.9 0.1 3.4 3 1 1 4 4 3 0 Myb/SANT-like DNA-binding domain FapA PF03961.13 OQR92054.1 - 2.3 6.7 8.5 0.33 9.5 3.6 1.9 2 0 0 2 2 2 0 Flagellar Assembly Protein A Tho2 PF11262.8 OQR92054.1 - 2.4 7.3 10.8 0.17 11.0 1.8 2.2 2 0 0 2 2 2 0 Transcription factor/nuclear export subunit protein 2 zf-C4H2 PF10146.9 OQR92054.1 - 3 8.1 8.1 0.35 11.1 3.6 1.7 2 0 0 2 2 2 0 Zinc finger-containing protein TolA_bind_tri PF16331.5 OQR92054.1 - 3.4 7.8 19.8 0.16 12.0 11.2 2.8 3 0 0 3 3 2 0 TolA binding protein trimerisation DUF724 PF05266.14 OQR92054.1 - 3.5 7.4 10.8 0.14 12.0 3.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF724) DUF3450 PF11932.8 OQR92054.1 - 5.7 6.2 17.6 0.27 10.5 9.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) KxDL PF10241.9 OQR92054.1 - 5.7 7.3 13.0 0.57 10.5 6.3 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein NPV_P10 PF05531.12 OQR92054.1 - 9.7 6.7 12.7 4.2 7.9 6.9 2.7 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein adh_short PF00106.25 OQR92089.1 - 7.1e-14 51.7 0.2 2.9e-09 36.7 0.0 2.2 1 1 1 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 OQR92089.1 - 5.3e-10 39.3 0.1 3.9e-07 29.9 0.0 2.1 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OQR92090.1 - 6.4e-33 113.9 0.3 8.5e-33 113.5 0.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OQR92090.1 - 6.1e-26 91.4 0.6 7.4e-26 91.1 0.6 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OQR92090.1 - 3e-06 27.2 0.2 5.3e-06 26.5 0.2 1.5 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 OQR92090.1 - 1.7e-05 24.8 0.2 2.6e-05 24.2 0.2 1.3 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 OQR92090.1 - 0.00062 19.4 0.3 0.0008 19.0 0.3 1.2 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.21 OQR92090.1 - 0.002 17.7 0.0 0.0037 16.8 0.0 1.6 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family ADH_zinc_N PF00107.26 OQR92090.1 - 0.0039 17.2 0.1 0.0068 16.4 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase RmlD_sub_bind PF04321.17 OQR92090.1 - 0.1 11.7 0.1 0.13 11.3 0.1 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain Ras PF00071.22 OQR92091.1 - 1.6e-53 180.6 0.1 2.2e-53 180.2 0.1 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OQR92091.1 - 1.3e-29 102.8 0.0 2.8e-29 101.8 0.0 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OQR92091.1 - 2e-14 53.4 0.0 2.9e-14 52.9 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 OQR92091.1 - 4.3e-05 23.5 0.1 0.019 14.9 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 OQR92091.1 - 4.3e-05 23.1 0.4 0.00017 21.2 0.1 1.9 1 1 0 2 2 2 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.18 OQR92091.1 - 0.00031 20.3 0.4 0.0015 18.1 0.4 1.9 1 1 0 1 1 1 1 Ferrous iron transport protein B MMR_HSR1 PF01926.23 OQR92091.1 - 0.00084 19.4 0.0 0.002 18.2 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 OQR92091.1 - 0.0016 17.9 0.0 0.0025 17.2 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 OQR92091.1 - 0.0032 16.8 0.1 0.0044 16.4 0.1 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region ATP_bind_1 PF03029.17 OQR92091.1 - 0.0057 16.5 0.2 0.041 13.7 0.1 2.0 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein PduV-EutP PF10662.9 OQR92091.1 - 0.0061 16.3 0.0 0.013 15.3 0.0 1.5 1 0 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation AAA_16 PF13191.6 OQR92091.1 - 0.054 13.9 0.1 0.11 12.8 0.1 1.7 1 1 0 1 1 1 0 AAA ATPase domain AAA_18 PF13238.6 OQR92091.1 - 0.085 13.4 0.1 0.17 12.5 0.1 1.6 1 1 0 1 1 1 0 AAA domain Bac_DnaA PF00308.18 OQR92091.1 - 0.088 12.6 0.1 0.17 11.7 0.0 1.7 2 1 0 2 2 2 0 Bacterial dnaA protein NACHT PF05729.12 OQR92091.1 - 0.15 12.0 0.2 0.33 10.9 0.2 1.8 1 1 0 1 1 1 0 NACHT domain Pkinase_Tyr PF07714.17 OQR92093.1 - 3.6e-30 105.1 0.0 4.6e-30 104.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OQR92093.1 - 1.4e-20 73.8 0.0 1.8e-20 73.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQR92095.1 - 7.1e-34 117.3 0.0 8e-34 117.1 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OQR92095.1 - 3.3e-33 115.2 0.0 4e-33 114.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Myb_DNA-binding PF00249.31 OQR92144.1 - 1.7e-08 34.5 0.1 4.3e-08 33.2 0.1 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OQR92144.1 - 0.013 15.7 0.3 0.056 13.7 0.1 2.2 2 0 0 2 2 2 0 Myb-like DNA-binding domain Peptidase_C98 PF15499.6 OQR92144.1 - 0.018 14.5 2.1 1.5 8.2 0.0 2.8 3 0 0 3 3 3 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase Myb_DNA-binding PF00249.31 OQR92145.1 - 1.1e-33 115.1 5.3 3.7e-10 39.8 0.3 3.5 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OQR92145.1 - 1.3e-10 41.4 6.8 0.0086 16.3 0.3 3.6 3 0 0 3 3 3 3 Myb-like DNA-binding domain DUF5009 PF16401.5 OQR92145.1 - 0.0014 18.2 1.8 0.0014 18.2 1.8 2.8 4 0 0 4 4 4 1 Domain of unknown function (DUF5009) DUF2165 PF09933.9 OQR92145.1 - 0.017 15.2 1.7 0.017 15.2 1.7 2.5 2 0 0 2 2 2 0 Predicted small integral membrane protein (DUF2165) DUF1624 PF07786.12 OQR92145.1 - 0.02 14.4 6.8 0.046 13.3 6.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1624) Importin_rep PF18773.1 OQR92145.1 - 0.26 11.0 3.5 45 3.9 0.1 3.8 3 0 0 3 3 3 0 Importin 13 repeat Myb_DNA-bind_7 PF15963.5 OQR92145.1 - 0.34 10.8 7.2 29 4.7 0.1 3.8 4 0 0 4 4 4 0 Myb DNA-binding like DASH_Spc19 PF08287.11 OQR92145.1 - 5.3 6.9 8.2 3.2 7.6 1.1 3.0 3 0 0 3 3 3 0 Spc19 HAGH_C PF16123.5 OQR92146.1 - 2.9e-22 79.0 1.4 6.7e-22 77.8 1.4 1.7 1 0 0 1 1 1 1 Hydroxyacylglutathione hydrolase C-terminus Lactamase_B PF00753.27 OQR92146.1 - 7.8e-07 29.3 4.7 1.9e-05 24.8 4.7 2.4 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 OQR92146.1 - 0.046 13.2 0.5 0.19 11.2 0.3 2.2 2 0 0 2 2 2 0 Beta-lactamase superfamily domain DUF553 PF04473.12 OQR92146.1 - 0.081 12.5 0.9 1 8.9 0.0 3.0 3 0 0 3 3 3 0 Transglutaminase-like domain DUF997 PF06196.12 OQR92146.1 - 0.55 10.3 3.8 13 5.8 0.0 3.9 4 0 0 4 4 4 0 Protein of unknown function (DUF997) Nitrate_red_gam PF02665.14 OQR92146.1 - 1.7 8.2 4.2 55 3.2 0.2 3.3 3 0 0 3 3 3 0 Nitrate reductase gamma subunit DUF3584 PF12128.8 OQR92147.1 - 0.012 13.2 37.8 0.016 12.8 37.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) HOOK PF05622.12 OQR92147.1 - 0.89 7.6 52.4 0.52 8.4 39.2 2.0 1 1 1 2 2 2 0 HOOK protein Apolipoprotein PF01442.18 OQR92147.1 - 3.5 7.5 40.8 3 7.7 19.0 2.5 1 1 1 2 2 2 0 Apolipoprotein A1/A4/E domain KASH_CCD PF14662.6 OQR92147.1 - 9.6 6.0 48.5 7.8 6.3 10.8 3.4 1 1 2 3 3 3 0 Coiled-coil region of CCDC155 or KASH Gelsolin PF00626.22 OQR92154.1 - 2.1e-84 277.4 0.0 4e-17 61.9 0.0 6.4 6 0 0 6 6 6 6 Gelsolin repeat DHHC PF01529.20 OQR92154.1 - 3.5e-32 111.3 14.0 3.5e-32 111.3 14.0 1.9 2 0 0 2 2 2 1 DHHC palmitoyltransferase VHP PF02209.19 OQR92154.1 - 7.1e-16 58.0 0.7 1.8e-15 56.7 0.7 1.8 1 0 0 1 1 1 1 Villin headpiece domain Use1 PF09753.9 OQR92155.1 - 0.00077 19.3 4.5 0.0022 17.8 4.5 1.7 1 1 0 1 1 1 1 Membrane fusion protein Use1 FAM184 PF15665.5 OQR92155.1 - 0.016 15.0 0.4 0.022 14.6 0.4 1.2 1 0 0 1 1 1 0 Family with sequence similarity 184, A and B SNARE PF05739.19 OQR92155.1 - 0.058 13.4 0.0 0.13 12.3 0.0 1.7 1 0 0 1 1 1 0 SNARE domain ArsR PF09824.9 OQR92155.1 - 0.071 12.7 0.1 0.1 12.2 0.1 1.3 1 1 0 1 1 1 0 ArsR transcriptional regulator Sec20 PF03908.13 OQR92155.1 - 0.16 11.9 3.2 2.8 7.9 2.8 2.5 1 1 1 2 2 2 0 Sec20 Myc_target_1 PF15179.6 OQR92155.1 - 0.22 11.4 3.7 0.046 13.6 0.7 1.5 1 1 1 2 2 2 0 Myc target protein 1 His_Phos_1 PF00300.22 OQR92156.1 - 4e-26 91.9 0.0 7.4e-12 45.4 0.0 3.1 2 2 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) TPR_2 PF07719.17 OQR92157.1 - 1.3e-30 103.0 5.3 0.00023 21.0 0.0 12.3 14 0 0 14 14 12 6 Tetratricopeptide repeat TPR_14 PF13428.6 OQR92157.1 - 5.6e-28 95.2 8.2 0.04 14.7 0.0 11.4 8 3 6 14 14 11 6 Tetratricopeptide repeat TPR_19 PF14559.6 OQR92157.1 - 2e-22 79.5 4.3 6.4e-06 26.6 0.0 8.0 8 1 0 8 8 7 3 Tetratricopeptide repeat TPR_16 PF13432.6 OQR92157.1 - 5e-21 75.1 1.3 0.001 19.7 0.1 8.6 9 1 0 9 9 8 4 Tetratricopeptide repeat TPR_8 PF13181.6 OQR92157.1 - 8.3e-19 66.2 8.9 0.00055 20.0 0.0 9.4 10 0 0 10 10 10 3 Tetratricopeptide repeat TPR_1 PF00515.28 OQR92157.1 - 5.1e-17 60.9 3.5 0.023 14.5 0.0 8.8 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_17 PF13431.6 OQR92157.1 - 5.3e-17 60.9 8.3 6.7e-05 23.0 0.0 9.3 11 0 0 11 11 9 3 Tetratricopeptide repeat TPR_11 PF13414.6 OQR92157.1 - 4.3e-15 55.1 8.1 3e-06 26.8 0.4 7.4 7 1 1 8 8 8 4 TPR repeat TPR_12 PF13424.6 OQR92157.1 - 1.2e-13 51.1 18.2 0.0025 18.0 0.1 10.4 7 2 3 10 10 10 2 Tetratricopeptide repeat TPR_6 PF13174.6 OQR92157.1 - 1.9e-11 43.8 8.2 5.5 7.8 0.1 9.8 10 0 0 10 10 10 1 Tetratricopeptide repeat ANAPC3 PF12895.7 OQR92157.1 - 7.7e-10 38.9 7.8 1.2e-05 25.4 0.4 5.0 6 0 0 6 6 6 2 Anaphase-promoting complex, cyclosome, subunit 3 Suf PF05843.14 OQR92157.1 - 2.1e-09 37.8 0.4 2.7e-07 30.9 0.0 3.4 2 1 1 3 3 3 2 Suppressor of forked protein (Suf) TPR_7 PF13176.6 OQR92157.1 - 3.9e-09 35.9 1.2 0.006 16.5 0.0 5.8 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_MalT PF17874.1 OQR92157.1 - 6.8e-07 29.0 7.0 3.7e-05 23.3 0.1 3.5 2 1 1 3 3 3 1 MalT-like TPR region TPR_9 PF13371.6 OQR92157.1 - 1.3e-06 28.4 2.5 0.1 12.7 0.0 5.4 4 3 0 4 4 4 1 Tetratricopeptide repeat BTAD PF03704.17 OQR92157.1 - 1.1e-05 26.0 6.1 0.0042 17.5 0.2 3.8 3 2 1 4 4 3 1 Bacterial transcriptional activator domain TPR_4 PF07721.14 OQR92157.1 - 2.4e-05 24.6 3.5 1.5 9.6 0.1 6.5 7 0 0 7 7 6 1 Tetratricopeptide repeat TPR_15 PF13429.6 OQR92157.1 - 7.7e-05 22.0 14.3 0.0009 18.5 0.0 4.0 3 1 1 5 5 4 2 Tetratricopeptide repeat PPR PF01535.20 OQR92157.1 - 0.00029 20.9 3.3 2.2e+02 2.4 0.0 7.9 9 0 0 9 9 7 0 PPR repeat NARP1 PF12569.8 OQR92157.1 - 0.0023 16.9 3.5 3.2 6.5 0.2 3.7 1 1 3 4 4 4 1 NMDA receptor-regulated protein 1 ChAPs PF09295.10 OQR92157.1 - 0.0026 16.8 2.7 0.4 9.6 1.1 2.7 1 1 1 2 2 2 2 ChAPs (Chs5p-Arf1p-binding proteins) ANAPC5 PF12862.7 OQR92157.1 - 0.026 14.6 0.1 0.35 11.0 0.0 2.8 2 1 1 3 3 2 0 Anaphase-promoting complex subunit 5 DUF4919 PF16266.5 OQR92157.1 - 0.067 13.1 0.0 0.76 9.7 0.0 2.6 3 0 0 3 3 2 0 Domain of unknown function (DUF4919) Mad3_BUB1_I PF08311.12 OQR92157.1 - 0.13 12.3 8.2 24 4.9 0.0 6.1 6 1 1 7 7 7 0 Mad3/BUB1 homology region 1 TPR_20 PF14561.6 OQR92157.1 - 0.24 11.8 1.4 9.1 6.7 0.0 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat Cellulase PF00150.18 OQR92171.1 - 4.9e-27 95.1 0.0 5.9e-27 94.8 0.0 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) FA_hydroxylase PF04116.13 OQR92172.1 - 4.4e-23 82.1 23.9 5.1e-23 81.9 21.4 1.9 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily DUF4913 PF16259.5 OQR92172.1 - 0.04 14.0 0.4 0.079 13.0 0.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4913) zf-CHY PF05495.12 OQR92175.1 - 7.1e-11 42.4 21.7 1e-10 41.9 21.7 1.2 1 0 0 1 1 1 1 CHY zinc finger RNA_POL_M_15KD PF02150.16 OQR92175.1 - 0.018 14.9 13.6 0.072 13.0 0.1 3.3 3 0 0 3 3 3 0 RNA polymerases M/15 Kd subunit TATR PF03430.13 OQR92175.1 - 0.057 11.8 0.0 0.063 11.7 0.0 1.0 1 0 0 1 1 1 0 Trans-activating transcriptional regulator zinc_ribbon_4 PF13717.6 OQR92175.1 - 0.073 13.0 10.7 0.31 11.0 0.2 2.9 2 1 0 2 2 2 0 zinc-ribbon domain Zn_Tnp_IS91 PF14319.6 OQR92175.1 - 5.5 7.1 18.6 0.49 10.5 7.4 2.1 1 1 1 2 2 2 0 Transposase zinc-binding domain EF-hand_1 PF00036.32 OQR92176.1 - 3e-21 73.3 15.2 1.1e-05 24.6 0.1 5.9 6 0 0 6 6 6 4 EF hand EF-hand_7 PF13499.6 OQR92176.1 - 9.4e-20 70.8 10.4 3.8e-07 30.5 1.7 4.7 4 0 0 4 4 4 3 EF-hand domain pair EF-hand_6 PF13405.6 OQR92176.1 - 2.7e-18 64.3 16.5 6.6e-05 22.5 0.9 6.9 6 0 0 6 6 6 4 EF-hand domain EF-hand_5 PF13202.6 OQR92176.1 - 3.3e-14 51.6 11.8 0.00034 20.0 0.8 5.1 5 0 0 5 5 5 4 EF hand EF-hand_8 PF13833.6 OQR92176.1 - 2.4e-10 40.1 15.4 0.00022 21.0 0.0 5.3 5 1 1 6 6 6 3 EF-hand domain pair CbiX PF01903.17 OQR92176.1 - 3.3e-08 33.8 0.0 1.4e-06 28.6 0.0 2.7 2 0 0 2 2 2 1 CbiX Epimerase PF01370.21 OQR92176.1 - 0.021 14.3 0.1 0.14 11.6 0.0 2.3 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family DHH PF01368.20 OQR92176.1 - 0.035 14.3 0.2 1.3 9.3 0.0 3.0 3 0 0 3 3 3 0 DHH family EFhand_Ca_insen PF08726.10 OQR92176.1 - 0.11 12.6 0.0 0.95 9.6 0.0 2.3 2 0 0 2 2 2 0 Ca2+ insensitive EF hand JmjN PF02375.17 OQR92176.1 - 0.15 12.1 0.1 0.74 9.8 0.1 2.3 1 0 0 1 1 1 0 jmjN domain NAD_binding_6 PF08030.12 OQR92177.1 - 1.2e-08 35.2 0.0 1.9e-08 34.6 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 OQR92177.1 - 1.1e-05 25.4 0.1 2.4e-05 24.4 0.1 1.6 1 0 0 1 1 1 1 FAD-binding domain Cmc1 PF08583.10 OQR92178.1 - 0.001 19.0 0.1 0.32 11.1 0.1 2.1 2 0 0 2 2 2 2 Cytochrome c oxidase biogenesis protein Cmc1 like COX6B PF02297.17 OQR92178.1 - 0.0038 17.4 0.5 0.0082 16.4 0.5 1.5 1 1 0 1 1 1 1 Cytochrome oxidase c subunit VIb COX17 PF05051.13 OQR92178.1 - 0.0082 16.5 0.1 3.2 8.2 0.0 2.3 2 0 0 2 2 2 2 Cytochrome C oxidase copper chaperone (COX17) CHCH PF06747.13 OQR92178.1 - 0.01 15.9 0.4 0.11 12.7 0.4 2.1 1 1 0 1 1 1 0 CHCH domain CX9C PF16860.5 OQR92178.1 - 0.035 14.1 0.7 3.8 7.6 0.1 2.1 2 0 0 2 2 2 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, UPF0203 PF05254.12 OQR92178.1 - 0.15 12.3 1.5 0.85 9.9 1.5 1.9 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0203) Pet191_N PF10203.9 OQR92178.1 - 0.18 12.1 1.1 4.3 7.7 1.2 2.1 1 1 1 2 2 2 0 Cytochrome c oxidase assembly protein PET191 Mt_ATP-synt_D PF05873.12 OQR92180.1 - 8.6e-15 54.9 0.2 1.2e-14 54.5 0.2 1.1 1 0 0 1 1 1 1 ATP synthase D chain, mitochondrial (ATP5H) DUF327 PF03885.13 OQR92180.1 - 0.098 12.6 0.1 0.41 10.6 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF327) HIG_1_N PF04588.13 OQR92181.1 - 7.8e-19 67.6 0.4 1e-18 67.3 0.4 1.2 1 0 0 1 1 1 1 Hypoxia induced protein conserved region SNARE PF05739.19 OQR92182.1 - 7.1e-15 54.8 0.3 1.6e-14 53.6 0.3 1.6 1 0 0 1 1 1 1 SNARE domain Syntaxin PF00804.25 OQR92182.1 - 8.1e-05 22.4 10.2 0.0027 17.4 0.2 2.6 3 0 0 3 3 3 2 Syntaxin SIL1 PF16782.5 OQR92182.1 - 0.13 11.4 4.4 1.3 8.2 0.3 2.3 2 1 0 2 2 2 0 Nucleotide exchange factor SIL1 T2SSF PF00482.23 OQR92182.1 - 0.32 11.0 3.3 0.17 11.8 0.7 1.8 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein F Use1 PF09753.9 OQR92182.1 - 0.61 9.8 7.3 1.8 8.2 7.3 1.8 1 1 0 1 1 1 0 Membrane fusion protein Use1 DUF16 PF01519.16 OQR92182.1 - 0.96 10.0 13.3 0.18 12.3 2.2 2.5 2 1 0 2 2 2 0 Protein of unknown function DUF16 AI-2E_transport PF01594.16 OQR92182.1 - 1.9 7.6 8.5 0.17 11.0 1.4 2.0 2 0 0 2 2 2 0 AI-2E family transporter bZIP_2 PF07716.15 OQR92184.1 - 0.14 12.3 5.6 0.23 11.6 5.6 1.3 1 0 0 1 1 1 0 Basic region leucine zipper zf-PARP PF00645.18 OQR92197.1 - 4.1e-07 30.8 0.0 5.3e-07 30.4 0.0 1.3 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region Myb_DNA-binding PF00249.31 OQR92198.1 - 2.2e-21 75.8 8.3 2.9e-08 33.8 0.9 3.4 3 1 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OQR92198.1 - 9.5e-18 64.2 6.1 3.1e-09 36.9 1.2 3.0 3 0 0 3 3 3 2 Myb-like DNA-binding domain Atg29_N PF18388.1 OQR92198.1 - 0.00074 19.3 4.4 0.027 14.3 1.1 2.4 2 0 0 2 2 2 2 Atg29 N-terminal domain Rap1_C PF11626.8 OQR92198.1 - 0.0012 18.9 0.0 0.56 10.3 0.7 2.3 1 1 1 2 2 2 2 TRF2-interacting telomeric protein/Rap1 - C terminal domain Myb_DNA-bind_6 PF13921.6 OQR92199.1 - 1.1e-11 44.7 5.4 3.6e-07 30.3 0.3 2.8 2 1 1 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 OQR92199.1 - 1.2e-08 35.0 5.5 1.1e-06 28.7 1.8 3.3 3 0 0 3 3 3 2 Myb-like DNA-binding domain DUF4411 PF14367.6 OQR92199.1 - 0.0037 17.2 0.5 0.54 10.1 0.1 2.1 2 0 0 2 2 2 2 Domain of unknown function (DUF4411) Myb_DNA-bind_4 PF13837.6 OQR92199.1 - 0.22 11.9 6.7 3.6 8.0 3.0 3.2 3 1 0 3 3 3 0 Myb/SANT-like DNA-binding domain MOZ_SAS PF01853.18 OQR92200.1 - 1.6e-81 272.2 0.8 2.3e-81 271.8 0.8 1.2 1 0 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 OQR92200.1 - 1.2e-18 66.4 0.5 1.2e-18 66.4 0.5 1.9 2 0 0 2 2 2 1 MYST family zinc finger domain Tudor-knot PF11717.8 OQR92200.1 - 7.7e-15 54.5 1.6 1.6e-14 53.5 1.6 1.6 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain PPL5 PF18168.1 OQR92200.1 - 0.18 11.1 3.6 0.28 10.5 3.6 1.2 1 0 0 1 1 1 0 Prim-pol family 5 zf-C2H2 PF00096.26 OQR92200.1 - 0.29 11.7 2.2 0.74 10.4 2.2 1.8 1 0 0 1 1 1 0 Zinc finger, C2H2 type FCP1_C PF09309.10 OQR92200.1 - 2.8 7.7 11.9 4.3 7.1 11.9 1.2 1 0 0 1 1 1 0 FCP1, C-terminal Myb_DNA-binding PF00249.31 OQR92201.1 - 4.3e-38 129.3 10.4 5e-12 45.8 1.5 3.5 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OQR92201.1 - 1.8e-34 117.8 8.8 2.6e-16 59.6 0.4 3.9 2 1 2 4 4 4 3 Myb-like DNA-binding domain Myb_DNA-bind_4 PF13837.6 OQR92201.1 - 0.00052 20.3 7.0 0.32 11.4 0.3 3.7 3 0 0 3 3 3 2 Myb/SANT-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OQR92201.1 - 0.0031 17.4 0.1 0.02 14.8 0.0 2.4 2 0 0 2 2 2 1 Myb DNA-binding like EF-hand_7 PF13499.6 OQR92201.1 - 0.0045 17.4 0.2 0.02 15.3 0.1 2.3 2 0 0 2 2 2 1 EF-hand domain pair Spore_III_AB PF09548.10 OQR92201.1 - 0.029 14.5 0.7 0.051 13.7 0.1 1.7 2 0 0 2 2 2 0 Stage III sporulation protein AB (spore_III_AB) PaaA_PaaC PF05138.12 OQR92201.1 - 0.054 12.6 0.4 0.38 9.9 0.3 2.2 1 1 0 1 1 1 0 Phenylacetic acid catabolic protein pPIWI_RE_Y PF18156.1 OQR92201.1 - 0.059 13.8 0.3 0.22 11.9 0.1 2.0 2 1 0 2 2 2 0 pPIWI_RE three-gene island domain Y Skp1 PF01466.19 OQR92201.1 - 0.084 13.0 2.4 4.8 7.4 0.2 3.7 3 1 0 3 3 3 0 Skp1 family, dimerisation domain Spt5_N PF11942.8 OQR92201.1 - 2.3 9.2 9.0 4.2 8.4 4.9 2.5 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal Atg29_N PF18388.1 OQR92201.1 - 4.5 7.2 6.0 5.2 7.0 0.4 3.2 3 0 0 3 3 3 0 Atg29 N-terminal domain Myb_DNA-bind_6 PF13921.6 OQR92202.1 - 8e-11 42.0 1.4 3.7e-10 39.9 0.2 2.4 3 0 0 3 3 3 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 OQR92202.1 - 3.5e-07 30.3 3.2 1.2e-06 28.5 0.2 2.7 3 0 0 3 3 3 1 Myb-like DNA-binding domain Atg29_N PF18388.1 OQR92202.1 - 0.00083 19.1 0.2 0.0066 16.2 0.0 2.1 1 1 1 2 2 2 1 Atg29 N-terminal domain Pkinase_Tyr PF07714.17 OQR92203.1 - 2.3e-26 92.7 0.0 1.8e-25 89.8 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OQR92203.1 - 2.3e-23 82.9 0.1 1.6e-22 80.1 0.0 2.2 2 1 0 2 2 2 1 Protein kinase domain Acyl-CoA_dh_1 PF00441.24 OQR92203.1 - 0.065 13.4 0.0 0.12 12.6 0.0 1.3 1 0 0 1 1 1 0 Acyl-CoA dehydrogenase, C-terminal domain LRR_8 PF13855.6 OQR92204.1 - 1.9e-21 75.5 15.5 2.7e-10 39.8 7.7 3.0 2 0 0 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 OQR92204.1 - 1.5e-14 53.8 23.8 5.1e-06 26.7 1.6 4.9 1 1 3 5 5 5 5 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 OQR92204.1 - 6.6e-05 22.9 12.7 2.4 9.0 0.1 6.2 4 2 0 4 4 4 3 Leucine Rich Repeat LRR_6 PF13516.6 OQR92204.1 - 0.00046 20.0 16.4 3.1 8.1 0.8 5.9 5 0 0 5 5 5 2 Leucine Rich repeat LRR_9 PF14580.6 OQR92204.1 - 0.006 16.1 11.4 0.27 10.7 0.7 3.0 1 1 2 3 3 3 3 Leucine-rich repeat LRR_3 PF07725.12 OQR92204.1 - 0.19 11.6 4.6 0.5 10.3 1.4 3.1 2 0 0 2 2 2 0 Leucine Rich Repeat TPR_12 PF13424.6 OQR92204.1 - 0.21 11.9 2.1 4.5 7.6 0.2 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 OQR92204.1 - 0.38 11.5 1.5 76 4.3 0.1 3.6 3 1 0 3 3 3 0 Tetratricopeptide repeat UME PF08064.13 OQR92204.1 - 2.3 8.2 6.3 0.36 10.8 0.6 2.6 3 0 0 3 3 3 0 UME (NUC010) domain Rdx PF10262.9 OQR92205.1 - 2.6e-08 33.9 0.0 3.4e-08 33.5 0.0 1.2 1 0 0 1 1 1 1 Rdx family Myb_DNA-binding PF00249.31 OQR92206.1 - 1.3e-20 73.3 4.4 1.5e-14 53.9 1.3 2.1 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OQR92206.1 - 2.7e-18 65.9 0.3 1.1e-13 51.2 0.1 2.1 1 1 1 2 2 2 2 Myb-like DNA-binding domain Atg29_N PF18388.1 OQR92206.1 - 0.0014 18.4 1.2 0.12 12.2 0.1 2.3 2 1 0 2 2 2 2 Atg29 N-terminal domain RAP80_UIM PF18282.1 OQR92206.1 - 0.009 15.8 0.1 0.015 15.0 0.1 1.4 1 0 0 1 1 1 1 RAP80 N-terminal ubiquitin interaction motif SLIDE PF09111.10 OQR92206.1 - 0.01 15.9 0.0 1.1 9.3 0.0 2.0 1 1 1 2 2 2 2 SLIDE Rap1_C PF11626.8 OQR92206.1 - 0.033 14.3 1.1 2 8.6 1.1 2.1 1 1 0 1 1 1 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain Myb_DNA-bind_4 PF13837.6 OQR92206.1 - 0.28 11.6 3.9 0.49 10.8 1.4 2.4 2 1 0 2 2 2 0 Myb/SANT-like DNA-binding domain NAD_binding_6 PF08030.12 OQR92214.1 - 4.2e-12 46.5 0.6 1.2e-09 38.5 0.1 2.8 2 1 0 2 2 2 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.19 OQR92214.1 - 4.4e-11 43.0 14.4 4.4e-11 43.0 14.4 2.3 2 1 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 OQR92214.1 - 4.9e-09 36.3 0.3 1.1e-08 35.1 0.1 1.8 2 0 0 2 2 2 1 FAD-binding domain DOMON PF03351.17 OQR92214.1 - 1.6e-05 25.1 0.2 3.9e-05 23.9 0.2 1.6 1 0 0 1 1 1 1 DOMON domain NAD_binding_1 PF00175.21 OQR92214.1 - 0.00078 20.1 0.0 0.0039 17.8 0.0 2.2 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 OQR92214.1 - 0.027 14.8 0.0 0.066 13.6 0.0 1.6 1 0 0 1 1 1 0 Oxidoreductase FAD-binding domain DUF4405 PF14358.6 OQR92214.1 - 3.8 8.1 21.3 0.98 10.0 11.0 3.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4405) EamA PF00892.20 OQR92215.1 - 1.4e-46 158.0 143.8 8.6e-13 48.6 12.0 7.1 7 0 0 7 7 7 7 EamA-like transporter family SLATT_1 PF18181.1 OQR92215.1 - 1.1 9.2 22.1 1.1 9.2 0.5 4.9 5 0 0 5 5 5 0 SMODS and SLOG-associating 2TM effector domain 1 Peptidase_A22B PF04258.13 OQR92219.1 - 1.2e-66 225.1 8.9 1.8e-66 224.6 8.9 1.2 1 0 0 1 1 1 1 Signal peptide peptidase PA PF02225.22 OQR92219.1 - 7.1e-05 22.8 0.0 0.00016 21.6 0.0 1.6 1 0 0 1 1 1 1 PA domain CTP_transf_like PF01467.26 OQR92220.1 - 1.2e-08 35.3 0.0 1.9e-08 34.6 0.0 1.3 1 0 0 1 1 1 1 Cytidylyltransferase-like FAD_syn PF06574.12 OQR92220.1 - 0.0074 16.2 0.3 0.013 15.4 0.3 1.3 1 0 0 1 1 1 1 FAD synthetase Ank_2 PF12796.7 OQR92221.1 - 2.9e-34 117.5 26.7 7.5e-09 36.1 1.1 6.9 2 2 6 8 8 8 8 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQR92221.1 - 9.3e-29 99.4 33.7 2.7e-05 24.6 0.4 10.3 6 3 4 10 10 10 8 Ankyrin repeats (many copies) Ank_5 PF13857.6 OQR92221.1 - 3e-13 49.7 29.4 0.055 13.8 0.0 11.6 4 3 10 14 14 14 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQR92221.1 - 9.5e-13 47.1 27.1 0.34 11.6 0.0 13.7 11 4 4 15 15 15 2 Ankyrin repeat DUF3447 PF11929.8 OQR92221.1 - 2.5e-05 24.1 0.1 0.49 10.4 0.0 4.6 3 2 3 7 7 7 2 Domain of unknown function (DUF3447) DUF5515 PF17635.2 OQR92221.1 - 0.052 14.2 0.8 48 4.7 0.0 4.3 5 0 0 5 5 5 0 Family of unknown function (DUF5515) Helicase_PWI PF18149.1 OQR92221.1 - 0.13 12.5 0.0 4 7.7 0.0 2.7 2 0 0 2 2 2 0 N-terminal helicase PWI domain Ank PF00023.30 OQR92221.1 - 0.19 12.2 24.3 5.1 7.7 0.1 8.9 5 4 3 8 8 8 0 Ankyrin repeat zf-C3Hc3H PF13891.6 OQR92221.1 - 0.31 11.5 1.8 0.54 10.7 0.3 2.2 3 0 0 3 3 3 0 Potential DNA-binding domain Tim17 PF02466.19 OQR92231.1 - 1.3e-23 83.5 0.7 2.4e-23 82.6 0.7 1.5 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family ThiF PF00899.21 OQR92231.1 - 4.9e-21 75.2 0.0 7.6e-21 74.6 0.0 1.6 1 1 0 1 1 1 1 ThiF family E1_4HB PF16191.5 OQR92231.1 - 1.9e-06 28.0 2.2 1.3 9.3 0.1 4.1 3 1 0 3 3 3 3 Ubiquitin-activating enzyme E1 four-helix bundle Citrate_synt PF00285.21 OQR92232.1 - 2.1e-104 349.5 0.0 2.7e-104 349.1 0.0 1.1 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain WD40 PF00400.32 OQR92233.1 - 2.8e-68 224.2 19.1 1.6e-09 38.2 0.0 8.8 8 1 0 8 8 8 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OQR92233.1 - 1.6e-23 82.8 1.7 0.00092 19.5 0.2 6.3 2 2 3 5 5 5 5 Anaphase-promoting complex subunit 4 WD40 domain NLE PF08154.12 OQR92233.1 - 1.1e-12 48.2 0.2 1.9e-12 47.5 0.2 1.4 1 0 0 1 1 1 1 NLE (NUC135) domain eIF2A PF08662.11 OQR92233.1 - 2.9e-08 33.8 0.2 0.03 14.2 0.0 4.2 3 2 2 5 5 5 3 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 OQR92233.1 - 3.6e-08 32.7 0.2 0.032 13.2 0.0 5.2 3 2 3 6 6 6 2 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 OQR92233.1 - 6.2e-06 26.0 6.3 2 8.5 0.0 5.0 6 0 0 6 6 6 3 WD40-like Beta Propeller Repeat Nup160 PF11715.8 OQR92233.1 - 1.7e-05 23.7 1.5 7.4 5.1 0.0 4.6 3 2 2 5 5 5 4 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 OQR92233.1 - 0.0024 16.7 0.3 0.93 8.2 0.1 2.6 2 1 0 2 2 2 2 Nup133 N terminal like Cytochrom_D1 PF02239.16 OQR92233.1 - 0.0024 16.5 0.0 0.62 8.5 0.0 3.1 3 1 1 4 4 4 2 Cytochrome D1 heme domain WD40_like PF17005.5 OQR92233.1 - 0.0041 16.5 0.0 1.5 8.1 0.0 3.5 4 0 0 4 4 4 1 WD40-like domain Gmad1 PF10647.9 OQR92233.1 - 0.0078 16.0 1.2 9.7 5.9 0.4 3.8 2 2 2 4 4 4 1 Lipoprotein LpqB beta-propeller domain IKI3 PF04762.12 OQR92233.1 - 0.037 12.0 0.4 0.34 8.8 0.0 2.4 2 1 0 3 3 3 0 IKI3 family Proteasome_A_N PF10584.9 OQR92233.1 - 0.11 12.2 4.3 26 4.6 0.1 4.0 4 0 0 4 4 4 0 Proteasome subunit A N-terminal signature DNA_ligase_A_M PF01068.21 OQR92234.1 - 1.6e-57 194.5 0.2 3.4e-57 193.4 0.2 1.6 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 OQR92234.1 - 3.8e-40 138.0 0.0 9.1e-40 136.8 0.0 1.7 1 0 0 1 1 1 1 DNA ligase N terminus mRNA_cap_enzyme PF01331.19 OQR92234.1 - 0.0021 17.9 0.1 0.18 11.6 0.1 2.5 1 1 0 1 1 1 1 mRNA capping enzyme, catalytic domain BSP_II PF05432.11 OQR92234.1 - 0.96 9.1 31.9 1.6 8.4 31.9 1.2 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) DEAD PF00270.29 OQR92235.1 - 2.9e-23 82.5 0.1 1.4e-22 80.3 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase Sec63 PF02889.16 OQR92235.1 - 2.4e-19 69.5 5.0 5.7e-19 68.3 5.0 1.7 1 1 0 1 1 1 1 Sec63 Brl domain ResIII PF04851.15 OQR92235.1 - 6.3e-06 26.3 0.0 2.4e-05 24.4 0.0 2.0 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit T2SSE PF00437.20 OQR92235.1 - 0.00014 21.1 0.0 0.0006 19.0 0.0 2.0 2 0 0 2 2 2 1 Type II/IV secretion system protein LSM PF01423.22 OQR92259.1 - 3.9e-18 64.9 0.4 6.7e-18 64.1 0.3 1.5 2 0 0 2 2 2 1 LSM domain Hfq PF17209.3 OQR92259.1 - 0.07 12.8 0.1 0.15 11.7 0.1 1.5 1 0 0 1 1 1 0 Hfq protein CLZ PF16526.5 OQR92261.1 - 0.2 12.1 4.0 0.27 11.6 2.1 2.0 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Uso1_p115_C PF04871.13 OQR92261.1 - 0.41 11.0 6.5 0.75 10.2 6.5 1.3 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region HALZ PF02183.18 OQR92261.1 - 0.93 9.8 5.8 5.1 7.4 2.1 2.3 2 0 0 2 2 2 0 Homeobox associated leucine zipper EphA2_TM PF14575.6 OQR92262.1 - 0.067 14.1 0.1 6.1 7.8 0.0 3.4 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain AAA_11 PF13086.6 OQR92263.1 - 3.1e-34 118.9 2.8 5.2e-23 82.2 0.1 3.7 2 2 1 3 3 3 2 AAA domain AAA_30 PF13604.6 OQR92263.1 - 9.3e-07 28.8 0.3 4.1e-06 26.6 0.3 2.2 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 OQR92263.1 - 2.8e-06 27.7 1.2 1.2e-05 25.6 1.2 2.2 2 1 0 2 2 2 1 AAA domain UvrD-helicase PF00580.21 OQR92263.1 - 0.016 14.8 0.4 0.086 12.4 0.0 2.3 2 1 0 2 2 2 0 UvrD/REP helicase N-terminal domain PhoH PF02562.16 OQR92263.1 - 0.028 13.9 0.1 0.061 12.8 0.1 1.5 1 0 0 1 1 1 0 PhoH-like protein ResIII PF04851.15 OQR92263.1 - 0.069 13.1 0.0 0.51 10.3 0.0 2.3 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_16 PF13191.6 OQR92263.1 - 0.087 13.2 0.1 0.32 11.4 0.1 1.9 1 0 0 1 1 1 0 AAA ATPase domain Helicase_RecD PF05127.14 OQR92263.1 - 0.11 12.4 2.3 0.77 9.6 0.4 3.0 1 1 1 2 2 2 0 Helicase ECH_1 PF00378.20 OQR92264.1 - 8.5e-84 280.8 1.5 9.7e-84 280.6 1.5 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 OQR92264.1 - 5.9e-37 127.9 1.2 1.4e-34 120.1 0.7 2.0 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase Peptidase_S49 PF01343.18 OQR92264.1 - 0.027 14.4 0.1 0.19 11.7 0.0 2.1 2 0 0 2 2 2 0 Peptidase family S49 NPV_P10 PF05531.12 OQR92276.1 - 0.00031 21.2 3.5 0.00031 21.2 3.5 7.7 6 3 2 8 8 8 2 Nucleopolyhedrovirus P10 protein DUF1664 PF07889.12 OQR92276.1 - 0.0045 17.0 1.2 0.0045 17.0 1.2 8.3 5 2 5 10 10 10 1 Protein of unknown function (DUF1664) Vip3A_N PF12495.8 OQR92276.1 - 0.015 15.2 0.2 0.015 15.2 0.2 4.4 4 1 1 5 5 5 0 Vegetative insecticide protein 3A N terminal UPF0184 PF03670.13 OQR92276.1 - 0.061 13.7 2.9 0.53 10.7 2.9 2.8 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0184) Anoctamin PF04547.12 OQR92289.1 - 1.7e-63 215.0 24.7 2.6e-63 214.4 24.7 1.2 1 0 0 1 1 1 1 Calcium-activated chloride channel FHA PF00498.26 OQR92289.1 - 2.7e-13 50.0 0.1 6.8e-13 48.8 0.1 1.8 1 0 0 1 1 1 1 FHA domain B12D PF06522.11 OQR92289.1 - 5.9e-08 32.4 0.0 2.3e-07 30.5 0.0 2.1 1 0 0 1 1 1 1 NADH-ubiquinone reductase complex 1 MLRQ subunit zf-C3HC4_2 PF13923.6 OQR92289.1 - 2e-06 27.5 15.4 2e-06 27.5 15.4 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 OQR92289.1 - 3.2e-06 27.4 15.2 3.2e-06 27.4 15.2 2.6 3 0 0 3 3 2 1 Ring finger domain zf-C3HC4 PF00097.25 OQR92289.1 - 4e-06 26.6 15.0 4e-06 26.6 15.0 2.1 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 OQR92289.1 - 7.1e-06 25.8 9.6 7.1e-06 25.8 9.6 2.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OQR92289.1 - 5.3e-05 23.2 12.4 0.00017 21.5 12.4 2.0 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 OQR92289.1 - 7.2e-05 22.9 16.9 0.00024 21.2 16.9 2.0 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING EF-hand_7 PF13499.6 OQR92289.1 - 0.00039 20.8 0.0 0.0023 18.4 0.0 2.4 2 0 0 2 2 1 1 EF-hand domain pair Yop-YscD_cpl PF16697.5 OQR92289.1 - 0.00071 19.8 0.0 0.0017 18.6 0.0 1.6 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain EF-hand_1 PF00036.32 OQR92289.1 - 0.0052 16.3 0.0 4 7.2 0.0 2.9 2 0 0 2 2 2 2 EF hand zf-RING_5 PF14634.6 OQR92289.1 - 0.0082 16.1 13.2 0.0082 16.1 13.2 2.7 3 0 0 3 3 3 1 zinc-RING finger domain EF-hand_6 PF13405.6 OQR92289.1 - 0.0091 15.9 0.0 1.3 9.1 0.0 3.0 2 0 0 2 2 2 1 EF-hand domain zf-rbx1 PF12678.7 OQR92289.1 - 0.0093 16.2 11.7 0.035 14.4 11.7 2.0 1 0 0 1 1 1 1 RING-H2 zinc finger domain Prok-RING_4 PF14447.6 OQR92289.1 - 0.89 9.5 17.5 0.1 12.5 12.2 2.2 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 Hydrolase_4 PF12146.8 OQR92290.1 - 3.6e-15 55.9 0.0 1.2e-14 54.1 0.0 1.8 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 OQR92290.1 - 2.3e-12 47.1 0.2 7.1e-10 38.9 0.2 2.2 1 1 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 OQR92290.1 - 1.6e-08 35.5 0.0 2.4e-08 34.8 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.18 OQR92290.1 - 0.0027 17.4 0.0 0.0033 17.1 0.0 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) DUF915 PF06028.11 OQR92290.1 - 0.013 14.8 0.0 0.025 13.9 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) DLH PF01738.18 OQR92290.1 - 0.049 13.2 0.1 0.44 10.1 0.1 2.4 2 1 0 2 2 2 0 Dienelactone hydrolase family Cutinase PF01083.22 OQR92290.1 - 0.076 13.0 0.2 0.21 11.5 0.0 1.7 2 0 0 2 2 2 0 Cutinase Oxidored_nitro PF00148.19 OQR92290.1 - 0.16 10.7 0.0 0.25 10.1 0.0 1.2 1 0 0 1 1 1 0 Nitrogenase component 1 type Oxidoreductase DUF4398 PF14346.6 OQR92291.1 - 0.39 11.4 5.7 9.5 6.9 1.2 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4398) MFS_1 PF07690.16 OQR92292.1 - 6.9e-17 61.4 19.2 1.8e-16 60.0 19.2 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily SepZ PF06066.11 OQR92292.1 - 2.3 8.5 5.4 5.4 7.3 0.1 2.4 2 0 0 2 2 2 0 SepZ PH PF00169.29 OQR92293.1 - 1.1e-23 83.8 1.8 1.8e-10 41.3 0.0 3.6 4 0 0 4 4 4 3 PH domain PH_9 PF15410.6 OQR92293.1 - 4.3e-05 23.9 0.8 0.056 13.8 0.1 3.1 2 0 0 2 2 2 2 Pleckstrin homology domain PH_11 PF15413.6 OQR92293.1 - 0.0002 21.8 2.3 1.7 9.1 0.1 4.1 3 2 0 3 3 3 2 Pleckstrin homology domain PH_2 PF08458.10 OQR92293.1 - 0.019 15.3 0.6 0.067 13.5 0.1 2.3 2 0 0 2 2 2 0 Plant pleckstrin homology-like region PH_13 PF16652.5 OQR92293.1 - 0.022 14.6 0.2 8.8 6.1 0.1 3.3 3 0 0 3 3 3 0 Pleckstrin homology domain PH_4 PF15404.6 OQR92293.1 - 0.53 10.1 3.4 73 3.1 0.0 3.9 3 1 0 4 4 4 0 Pleckstrin homology domain Ank_2 PF12796.7 OQR92294.1 - 8.4e-47 157.7 4.8 8.4e-13 48.7 0.1 5.9 4 2 2 6 6 6 5 Ankyrin repeats (3 copies) Ank PF00023.30 OQR92294.1 - 5.7e-39 130.9 13.3 0.00013 22.2 0.0 11.4 11 1 0 11 11 11 8 Ankyrin repeat Ank_4 PF13637.6 OQR92294.1 - 2.9e-38 129.7 7.4 1.7e-07 31.7 0.0 8.6 5 3 3 9 9 9 8 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQR92294.1 - 1.5e-33 111.1 18.6 0.00061 20.1 0.0 11.8 12 0 0 12 12 12 8 Ankyrin repeat Ank_5 PF13857.6 OQR92294.1 - 1.6e-29 101.6 13.5 1.2e-05 25.4 0.0 8.5 4 3 5 10 10 10 8 Ankyrin repeats (many copies) Shigella_OspC PF06128.11 OQR92294.1 - 0.047 13.4 1.2 5.1 6.7 0.1 3.4 3 1 1 4 4 4 0 Shigella flexneri OspC protein BH4 PF02180.17 OQR92294.1 - 0.42 10.5 0.0 0.42 10.5 0.0 1.6 2 0 0 2 2 2 0 Bcl-2 homology region 4 Lactamase_B PF00753.27 OQR92295.1 - 1e-07 32.2 0.1 0.00026 21.1 0.0 2.2 2 0 0 2 2 2 2 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 OQR92295.1 - 0.0019 17.7 0.2 0.038 13.5 0.0 2.1 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Ank_2 PF12796.7 OQR92296.1 - 2.8e-47 159.2 4.4 4.5e-16 59.2 0.1 4.7 1 1 3 5 5 5 5 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OQR92296.1 - 6.1e-37 121.4 8.2 3.5e-05 23.9 0.0 9.1 9 0 0 9 9 9 8 Ankyrin repeat Ank_4 PF13637.6 OQR92296.1 - 7.7e-37 125.2 4.0 2.7e-11 43.7 0.0 5.5 4 1 0 5 5 5 5 Ankyrin repeats (many copies) Ank PF00023.30 OQR92296.1 - 5.2e-33 112.1 17.5 3.1e-06 27.4 0.1 8.8 8 1 1 9 9 9 7 Ankyrin repeat Ank_5 PF13857.6 OQR92296.1 - 5.1e-28 96.8 11.8 6.9e-06 26.2 0.1 8.0 1 1 6 8 8 8 8 Ankyrin repeats (many copies) PRAI PF00697.22 OQR92300.1 - 0.22 11.3 0.0 0.3 10.9 0.0 1.4 1 0 0 1 1 1 0 N-(5'phosphoribosyl)anthranilate (PRA) isomerase DCP1 PF06058.13 OQR92301.1 - 2.1e-34 117.9 0.1 3.5e-34 117.2 0.1 1.4 1 0 0 1 1 1 1 Dcp1-like decapping family Exo_endo_phos PF03372.23 OQR92301.1 - 2.3e-07 30.6 0.0 4.4e-07 29.7 0.0 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family baeRF_family5 PF18846.1 OQR92301.1 - 1.7 8.8 4.0 42 4.3 0.1 3.5 4 0 0 4 4 4 0 Bacterial archaeo-eukaryotic release factor family 5 PI3_PI4_kinase PF00454.27 OQR92302.1 - 6.3e-30 104.8 0.3 6.6e-21 75.2 0.0 2.5 1 1 1 2 2 2 2 Phosphatidylinositol 3- and 4-kinase FYVE PF01363.21 OQR92302.1 - 5.4e-19 68.1 2.2 5.4e-19 68.1 2.2 2.7 2 1 0 2 2 2 1 FYVE zinc finger PI3Ka PF00613.20 OQR92302.1 - 1.4e-07 31.1 1.2 3.1e-06 26.7 0.4 2.6 2 1 0 2 2 2 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) DUF4135 PF13575.6 OQR92302.1 - 0.013 14.8 0.0 0.024 14.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4135) FYVE_2 PF02318.16 OQR92302.1 - 0.016 15.4 1.7 0.016 15.4 1.7 2.5 2 0 0 2 2 2 0 FYVE-type zinc finger F-box-like PF12937.7 OQR92302.1 - 0.032 14.1 0.4 0.096 12.6 0.4 1.8 1 0 0 1 1 1 0 F-box-like E_raikovi_mat PF06360.11 OQR92302.1 - 0.12 12.8 0.6 0.34 11.4 0.6 1.8 1 0 0 1 1 1 0 Euplotes raikovi mating pheromone IBR PF01485.21 OQR92302.1 - 5.4 7.3 7.6 2.9 8.2 4.1 2.3 2 0 0 2 2 2 0 IBR domain, a half RING-finger domain HhH-GPD PF00730.25 OQR92303.1 - 2.9e-13 50.2 0.0 4.7e-13 49.5 0.0 1.3 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 OQR92303.1 - 0.00032 20.4 0.6 0.0021 17.8 0.1 2.8 2 1 0 2 2 2 1 Helix-hairpin-helix motif EndIII_4Fe-2S PF10576.9 OQR92303.1 - 0.0098 16.2 4.2 0.016 15.6 4.2 1.4 1 0 0 1 1 1 1 Iron-sulfur binding domain of endonuclease III CNTF PF01110.17 OQR92303.1 - 0.071 12.5 0.1 0.11 11.9 0.1 1.2 1 0 0 1 1 1 0 Ciliary neurotrophic factor HHH_5 PF14520.6 OQR92303.1 - 0.074 13.7 0.7 2.5 8.8 0.1 2.6 2 0 0 2 2 2 0 Helix-hairpin-helix domain Endonuc-FokI_C PF09254.11 OQR92303.1 - 0.096 11.9 0.0 0.14 11.4 0.0 1.3 1 0 0 1 1 1 0 Restriction endonuclease FokI, C terminal DUF2400 PF09674.10 OQR92303.1 - 0.1 12.6 0.5 0.4 10.6 0.0 2.1 1 1 0 2 2 2 0 Protein of unknown function (DUF2400) PPR_2 PF13041.6 OQR92304.1 - 1.9e-14 53.6 1.0 0.062 13.5 0.0 7.8 6 1 2 8 8 8 4 PPR repeat family PPR PF01535.20 OQR92304.1 - 1.4e-10 40.6 0.5 2.1 8.8 0.0 7.4 8 0 0 8 8 8 4 PPR repeat PPR_3 PF13812.6 OQR92304.1 - 3.5e-05 23.8 0.3 0.53 10.4 0.0 4.9 5 0 0 5 5 5 1 Pentatricopeptide repeat domain PPR_long PF17177.4 OQR92304.1 - 0.00036 20.0 6.3 7.5 5.8 0.0 6.0 6 1 0 6 6 6 2 Pentacotripeptide-repeat region of PRORP Ank_4 PF13637.6 OQR92305.1 - 3.6e-21 75.2 1.7 2.2e-08 34.5 0.1 4.2 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 OQR92305.1 - 7.3e-18 64.4 0.5 1.2e-08 35.0 0.0 4.5 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 OQR92305.1 - 1.2e-17 64.3 0.2 1.5e-15 57.5 0.1 2.3 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OQR92305.1 - 1.3e-14 52.8 4.7 1.1e-05 25.4 0.1 4.6 5 0 0 5 5 5 3 Ankyrin repeat Ank PF00023.30 OQR92305.1 - 1.9e-13 50.2 0.5 0.0056 17.1 0.1 3.6 3 0 0 3 3 3 3 Ankyrin repeat CHASE3 PF05227.13 OQR92305.1 - 0.092 12.7 0.0 12 5.8 0.0 2.3 2 0 0 2 2 2 0 CHASE3 domain HSP70 PF00012.20 OQR92306.1 - 5.1e-243 807.7 14.4 5.7e-243 807.5 14.4 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 OQR92306.1 - 2e-13 49.9 2.0 2e-13 49.9 0.2 1.9 2 0 0 2 2 2 1 MreB/Mbl protein Radial_spoke_3 PF06098.11 OQR92306.1 - 5.8e-05 22.5 6.1 5.8e-05 22.5 6.1 1.7 2 0 0 2 2 2 1 Radial spoke protein 3 FGGY_C PF02782.16 OQR92306.1 - 0.0031 17.2 0.4 0.021 14.6 0.0 2.5 4 0 0 4 4 4 1 FGGY family of carbohydrate kinases, C-terminal domain Hydantoinase_A PF01968.18 OQR92306.1 - 0.025 13.8 0.2 0.067 12.4 0.2 1.7 1 0 0 1 1 1 0 Hydantoinase/oxoprolinase StbA PF06406.11 OQR92306.1 - 0.096 11.9 2.0 0.13 11.4 0.0 2.2 3 0 0 3 3 3 0 StbA protein YlzJ PF14035.6 OQR92306.1 - 0.15 12.3 0.1 0.85 9.9 0.1 2.3 1 0 0 1 1 1 0 YlzJ-like protein LANC_like PF05147.13 OQR92306.1 - 0.55 8.8 1.5 0.98 7.9 1.5 1.3 1 0 0 1 1 1 0 Lanthionine synthetase C-like protein PspB PF06667.12 OQR92306.1 - 2.2 8.4 3.7 1.1 9.3 0.3 2.2 2 0 0 2 2 2 0 Phage shock protein B DUF4537 PF15057.6 OQR92346.1 - 2.3e-05 24.4 0.0 3.7 7.6 0.0 4.3 3 1 0 4 4 4 3 Domain of unknown function (DUF4537) TUDOR_5 PF18359.1 OQR92346.1 - 0.18 11.6 0.3 11 5.8 0.0 3.3 4 0 0 4 4 4 0 Histone methyltransferase Tudor domain 1 Thioredoxin_4 PF13462.6 OQR92347.1 - 1.9e-07 31.4 0.0 2.9e-07 30.8 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin DSBA PF01323.20 OQR92347.1 - 1.2e-05 25.2 0.4 0.00043 20.1 0.1 2.5 1 1 1 2 2 2 2 DSBA-like thioredoxin domain PH PF00169.29 OQR92348.1 - 0.0007 20.1 0.0 0.0012 19.3 0.0 1.5 1 1 0 1 1 1 1 PH domain DNA_pol3_a_NII PF11490.8 OQR92348.1 - 0.042 13.7 0.0 0.075 12.9 0.0 1.3 1 0 0 1 1 1 0 DNA polymerase III polC-type N-terminus II CNOT1_TTP_bind PF16417.5 OQR92348.1 - 0.057 12.6 0.1 0.073 12.2 0.1 1.1 1 0 0 1 1 1 0 CCR4-NOT transcription complex subunit 1 TTP binding domain Spc7 PF08317.11 OQR92349.1 - 0.0058 15.6 2.1 0.0058 15.6 2.1 2.4 1 1 1 2 2 2 1 Spc7 kinetochore protein DUF1699 PF08004.11 OQR92349.1 - 0.022 14.4 0.5 0.076 12.7 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1699) DUF1933 PF09147.10 OQR92349.1 - 0.035 13.7 0.4 0.066 12.8 0.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1933) Phage_TAC_2 PF06894.11 OQR92349.1 - 0.061 13.1 7.1 0.82 9.5 2.5 3.2 2 1 1 3 3 3 0 Bacteriophage lambda tail assembly chaperone, TAC, protein G DUF957 PF06117.11 OQR92349.1 - 0.36 10.4 1.1 1.8 8.2 0.0 2.6 3 0 0 3 3 3 0 Enterobacterial protein of unknown function (DUF957) Mvb12 PF09452.10 OQR92349.1 - 0.9 10.0 2.7 30 5.1 0.1 3.0 3 1 0 3 3 3 0 ESCRT-I subunit Mvb12 DivIVA PF05103.13 OQR92349.1 - 1.1 9.3 21.9 0.043 13.9 3.5 3.8 4 0 0 4 4 4 0 DivIVA protein DUF5082 PF16888.5 OQR92349.1 - 2.1 8.7 13.1 0.41 10.9 1.5 3.3 2 1 2 4 4 4 0 Domain of unknown function (DUF5082) DUF416 PF04222.12 OQR92349.1 - 2.6 7.4 9.0 0.19 11.1 2.5 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF416) Fib_alpha PF08702.10 OQR92349.1 - 3.6 7.8 10.7 1.8 8.7 0.9 2.9 1 1 2 4 4 4 0 Fibrinogen alpha/beta chain family CdvA PF18822.1 OQR92349.1 - 4.1 7.3 9.2 2.6 7.9 1.8 3.2 3 1 0 3 3 3 0 CdvA-like coiled-coil domain Aida_N PF08910.10 OQR92349.1 - 6 7.3 7.8 1.5 9.3 0.7 2.8 2 1 1 3 3 3 0 Aida N-terminus DUF3584 PF12128.8 OQR92349.1 - 8.9 3.7 18.8 0.73 7.3 11.5 1.8 1 1 0 2 2 2 0 Protein of unknown function (DUF3584) CREPT PF16566.5 OQR92349.1 - 9.3 6.4 13.2 0.3 11.2 2.0 2.9 1 1 2 3 3 3 0 Cell-cycle alteration and expression-elevated protein in tumour Cation_ATPase PF13246.6 OQR92351.1 - 4.7e-09 36.2 0.2 1.1e-07 31.9 0.0 2.9 2 1 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 OQR92351.1 - 3.9e-07 30.6 0.0 0.0024 18.2 0.0 2.4 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 OQR92351.1 - 9.5e-06 25.2 0.0 1.8e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 E1-E2 ATPase PGBA_C PF15437.6 OQR92351.1 - 0.33 11.3 3.9 0.68 10.3 3.9 1.4 1 0 0 1 1 1 0 Plasminogen-binding protein pgbA C-terminal TPR_12 PF13424.6 OQR92370.1 - 0.0014 18.9 0.0 1.7 9.0 0.0 2.9 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_10 PF13374.6 OQR92370.1 - 0.0045 16.8 0.1 7.8 6.5 0.0 4.2 5 0 0 5 5 5 1 Tetratricopeptide repeat Pex19 PF04614.12 OQR92371.1 - 3.8e-38 131.6 24.2 4.8e-38 131.3 23.4 1.5 1 1 0 1 1 1 1 Pex19 protein family ZYG-11_interact PF05884.12 OQR92371.1 - 0.082 12.3 2.2 0.18 11.2 0.2 2.3 1 1 1 2 2 2 0 Interactor of ZYG-11 BACK PF07707.15 OQR92371.1 - 0.12 12.5 1.5 0.19 11.8 0.2 2.0 2 0 0 2 2 2 0 BTB And C-terminal Kelch UPF0149 PF03695.13 OQR92371.1 - 0.21 11.9 5.6 4.8 7.4 4.9 2.2 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0149) DUF1397 PF07165.11 OQR92371.1 - 0.25 10.7 2.8 4.2 6.7 0.0 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1397) Dynein_light PF01221.18 OQR92371.1 - 0.66 10.3 5.1 3.1 8.2 0.2 2.5 2 0 0 2 2 2 0 Dynein light chain type 1 HD_3 PF13023.6 OQR92371.1 - 1.2 9.0 8.0 0.27 11.2 1.7 2.5 1 1 0 2 2 2 0 HD domain SesA PF17107.5 OQR92371.1 - 4.1 7.6 5.3 12 6.1 0.8 2.6 2 1 1 3 3 3 0 N-terminal domain on NACHT_NTPase and P-loop NTPases SpoU_methylase PF00588.19 OQR92375.1 - 1.8e-15 57.3 0.0 3.8e-15 56.3 0.0 1.5 2 0 0 2 2 2 1 SpoU rRNA Methylase family Ank_2 PF12796.7 OQR92376.1 - 5.4e-15 55.8 0.0 1.3e-07 32.0 0.0 2.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 OQR92376.1 - 2.8e-14 52.8 0.2 4.7e-06 26.8 0.1 4.6 4 0 0 4 4 4 4 Ankyrin repeat Ank_3 PF13606.6 OQR92376.1 - 6e-12 44.6 0.0 0.14 12.8 0.0 4.9 4 0 0 4 4 4 3 Ankyrin repeat Ank_4 PF13637.6 OQR92376.1 - 7.4e-12 45.5 0.1 0.38 11.4 0.0 4.8 3 1 1 4 4 4 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 OQR92376.1 - 2.5e-07 30.8 0.3 0.014 15.7 0.0 4.6 2 2 3 5 5 5 2 Ankyrin repeats (many copies) FYVE PF01363.21 OQR92376.1 - 0.00046 20.3 9.0 0.002 18.2 9.0 2.0 1 1 0 1 1 1 1 FYVE zinc finger Ank_2 PF12796.7 OQR92409.1 - 2.2e-14 53.8 0.0 7.2e-09 36.1 0.0 2.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OQR92409.1 - 1.7e-12 46.3 0.1 0.00061 20.1 0.0 3.6 3 0 0 3 3 3 3 Ankyrin repeat Ank PF00023.30 OQR92409.1 - 1.5e-10 41.0 1.2 0.0017 18.7 0.0 3.5 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.6 OQR92409.1 - 6.5e-10 39.1 1.6 0.00037 20.7 0.1 3.5 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 OQR92409.1 - 1.9e-09 37.8 0.0 0.00029 21.4 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Tim44 PF04280.15 OQR92409.1 - 0.11 12.6 0.0 0.17 12.0 0.0 1.3 1 0 0 1 1 1 0 Tim44-like domain Cyclase PF04199.13 OQR92410.1 - 4.2e-47 159.8 0.5 6.1e-23 81.6 0.1 2.2 2 0 0 2 2 2 2 Putative cyclase Cupin_3 PF05899.12 OQR92410.1 - 0.0072 16.0 0.3 5.4 6.8 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF861) DUF4588 PF15251.6 OQR92410.1 - 0.017 14.9 0.1 8.7 6.0 0.0 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4588) Abhydro_lipase PF04083.16 OQR92410.1 - 0.17 11.5 0.0 0.54 9.9 0.0 1.9 2 0 0 2 2 2 0 Partial alpha/beta-hydrolase lipase region DUF4141 PF13605.6 OQR92410.1 - 0.41 9.9 2.2 9 5.6 0.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4141) CCDC24 PF15669.5 OQR92411.1 - 9.1e-29 100.8 1.3 2.4e-28 99.4 1.3 1.8 1 1 0 1 1 1 1 Coiled-coil domain-containing protein 24 family GvpL_GvpF PF06386.11 OQR92411.1 - 0.069 13.1 1.1 0.11 12.5 1.1 1.3 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF DHR10 PF18595.1 OQR92411.1 - 0.17 12.0 11.6 0.39 10.8 7.6 2.5 2 0 0 2 2 2 0 Designed helical repeat protein 10 domain Dynactin_p22 PF07426.11 OQR92411.1 - 0.54 10.1 8.2 0.3 10.9 0.3 2.6 2 1 0 2 2 2 0 Dynactin subunit p22 DUF2982 PF11201.8 OQR92411.1 - 0.58 9.7 2.6 20 4.7 0.1 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2982) AAA_23 PF13476.6 OQR92411.1 - 0.78 10.2 9.4 0.093 13.2 3.3 2.0 2 0 0 2 2 2 0 AAA domain Remorin_C PF03763.13 OQR92411.1 - 2 8.3 6.5 0.65 9.9 2.5 2.1 2 1 1 3 3 3 0 Remorin, C-terminal region NPV_P10 PF05531.12 OQR92411.1 - 2.2 8.8 7.4 3.8 8.1 0.0 3.4 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein Peptidase_M13_N PF05649.13 OQR92412.1 - 6.2e-79 266.4 0.1 7.9e-79 266.1 0.1 1.1 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13 PF01431.21 OQR92412.1 - 5.1e-69 232.0 0.0 8.9e-69 231.2 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M48 PF01435.18 OQR92412.1 - 0.024 14.4 0.1 0.13 12.0 0.0 2.1 3 0 0 3 3 3 0 Peptidase family M48 C_GCAxxG_C_C PF09719.10 OQR92412.1 - 0.053 13.8 0.0 0.13 12.6 0.0 1.6 1 0 0 1 1 1 0 Putative redox-active protein (C_GCAxxG_C_C) PEN-2 PF10251.9 OQR92413.1 - 5.1e-16 58.9 2.7 6.4e-16 58.6 2.7 1.1 1 0 0 1 1 1 1 Presenilin enhancer-2 subunit of gamma secretase EamA PF00892.20 OQR92413.1 - 0.13 12.4 6.6 0.17 12.1 5.4 1.5 1 1 1 2 2 2 0 EamA-like transporter family C2 PF00168.30 OQR92425.1 - 1.5e-17 63.8 0.0 3.3e-17 62.7 0.0 1.6 1 0 0 1 1 1 1 C2 domain LRR_9 PF14580.6 OQR92425.1 - 4e-14 52.5 0.5 1.1e-13 51.0 0.5 1.8 1 0 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.7 OQR92425.1 - 4.3e-09 36.5 9.3 0.00011 22.5 0.3 4.3 2 1 3 5 5 5 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 OQR92425.1 - 0.00016 21.4 1.7 0.00016 21.4 1.7 3.8 2 1 1 3 3 3 1 Leucine rich repeat LRR_1 PF00560.33 OQR92425.1 - 0.013 15.9 6.7 7.8 7.5 0.0 4.9 3 1 0 3 3 3 0 Leucine Rich Repeat Dpy-30 PF05186.13 OQR92425.1 - 0.06 13.1 1.9 0.68 9.7 0.7 2.4 2 0 0 2 2 2 0 Dpy-30 motif LRR_6 PF13516.6 OQR92425.1 - 3.2 8.0 6.3 1.2e+02 3.1 0.0 4.2 4 0 0 4 4 4 0 Leucine Rich repeat DUF4886 PF16227.5 OQR92426.1 - 0.017 14.3 0.7 0.049 12.8 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4886) DUF977 PF06163.11 OQR92426.1 - 0.054 13.4 0.4 0.13 12.2 0.1 1.8 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF977) Swi5 PF07061.11 OQR92426.1 - 0.07 13.2 0.3 2.1 8.5 0.0 2.9 3 0 0 3 3 3 0 Swi5 Dna2 PF08696.11 OQR92427.1 - 0.061 13.1 1.1 1.2 8.9 0.3 2.2 2 0 0 2 2 2 0 DNA replication factor Dna2 JAKMIP_CC3 PF16034.5 OQR92427.1 - 0.1 12.6 2.2 0.17 11.8 2.2 1.3 1 0 0 1 1 1 0 JAKMIP CC3 domain HisKA_3 PF07730.13 OQR92427.1 - 0.36 11.4 2.8 2.7 8.6 0.1 2.6 1 1 1 2 2 2 0 Histidine kinase CCDC-167 PF15188.6 OQR92427.1 - 0.46 10.9 2.5 0.7 10.3 1.8 1.7 1 1 0 1 1 1 0 Coiled-coil domain-containing protein 167 bZIP_2 PF07716.15 OQR92427.1 - 1.4 9.0 11.8 18 5.5 0.1 2.7 2 1 0 2 2 2 0 Basic region leucine zipper RrnaAD PF00398.20 OQR92428.1 - 4.2e-06 26.0 0.0 9.5e-06 24.9 0.0 1.5 2 0 0 2 2 2 1 Ribosomal RNA adenine dimethylase Methyltransf_25 PF13649.6 OQR92428.1 - 0.024 15.3 0.0 0.052 14.3 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain PCMT PF01135.19 OQR92428.1 - 0.068 12.9 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) SPRY PF00622.28 OQR92429.1 - 1.8e-21 76.4 0.0 3.4e-21 75.6 0.0 1.5 1 0 0 1 1 1 1 SPRY domain PCMT PF01135.19 OQR92429.1 - 2.4e-14 53.6 0.0 4.4e-14 52.7 0.0 1.4 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.6 OQR92429.1 - 0.0018 18.1 0.0 0.0045 16.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 OQR92429.1 - 0.031 13.6 0.0 0.058 12.7 0.0 1.3 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase GlgS PF08971.11 OQR92429.1 - 0.13 12.3 0.3 0.56 10.3 0.3 2.0 2 0 0 2 2 2 0 Glycogen synthesis protein CorA PF01544.18 OQR92430.1 - 0.013 14.8 5.9 2.5 7.4 1.1 2.9 1 1 1 2 2 2 0 CorA-like Mg2+ transporter protein SNARE PF05739.19 OQR92430.1 - 0.021 14.8 0.2 0.021 14.8 0.2 1.8 2 0 0 2 2 2 0 SNARE domain Use1 PF09753.9 OQR92430.1 - 0.023 14.4 1.4 0.03 14.1 1.4 1.2 1 0 0 1 1 1 0 Membrane fusion protein Use1 DUF2857 PF11198.8 OQR92430.1 - 0.034 13.9 0.5 0.065 13.0 0.3 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2857) Methyltransf_4 PF02390.17 OQR92431.1 - 5.1e-09 35.8 0.0 6.7e-09 35.4 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_25 PF13649.6 OQR92431.1 - 5.8e-07 30.1 0.1 9.8e-07 29.4 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OQR92431.1 - 6.7e-06 26.0 0.1 8.2e-06 25.7 0.1 1.2 1 0 0 1 1 1 1 Methyltransferase domain DOT1 PF08123.13 OQR92431.1 - 8.3e-06 25.5 0.0 1.2e-05 25.0 0.0 1.2 1 0 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_18 PF12847.7 OQR92431.1 - 1e-05 25.5 0.0 1.5e-05 24.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 OQR92431.1 - 1.5e-05 24.4 0.0 1.9e-05 24.1 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_11 PF08241.12 OQR92431.1 - 0.0003 21.4 0.0 0.00048 20.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OQR92431.1 - 0.00076 19.4 0.0 0.00076 19.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MetW PF07021.12 OQR92431.1 - 0.0012 18.4 0.1 0.0018 17.9 0.1 1.3 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_32 PF13679.6 OQR92431.1 - 0.0021 18.1 0.0 0.0032 17.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OQR92431.1 - 0.0034 18.1 0.0 0.0051 17.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 OQR92431.1 - 0.0051 16.2 0.0 0.0061 16.0 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) RrnaAD PF00398.20 OQR92431.1 - 0.13 11.3 0.0 0.17 10.9 0.0 1.3 1 1 0 1 1 1 0 Ribosomal RNA adenine dimethylase DsbC PF11412.8 OQR92432.1 - 0.012 15.7 0.0 0.019 15.0 0.0 1.3 1 0 0 1 1 1 0 Disulphide bond corrector protein DsbC tRNA-synt_1b PF00579.25 OQR92448.1 - 3.3e-60 203.9 0.0 5e-60 203.3 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) Pkinase_Tyr PF07714.17 OQR92448.1 - 2.1e-40 138.6 0.0 3.4e-40 138.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OQR92448.1 - 1.3e-39 136.2 0.0 2.3e-39 135.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain S4 PF01479.25 OQR92448.1 - 0.0051 16.5 0.0 0.011 15.4 0.0 1.6 1 0 0 1 1 1 1 S4 domain TyrRSs_C PF16714.5 OQR92448.1 - 0.14 11.9 0.2 21 5.0 0.0 2.4 1 1 1 2 2 2 0 Tyrosyl-tRNA synthetase C-terminal domain CHRD PF07452.12 OQR92448.1 - 0.15 13.1 0.3 0.39 11.7 0.3 1.7 1 0 0 1 1 1 0 CHRD domain zf-C3HC4_2 PF13923.6 OQR92449.1 - 8.2e-07 28.8 9.1 8.2e-07 28.8 9.1 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.6 OQR92449.1 - 8.8e-07 28.7 5.3 8.8e-07 28.7 5.3 1.7 2 0 0 2 2 2 1 zf-RING of BARD1-type protein zf-C3HC4 PF00097.25 OQR92449.1 - 2.3e-06 27.4 8.0 2.3e-06 27.4 8.0 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 OQR92449.1 - 0.00011 22.4 9.6 0.00011 22.4 9.6 2.1 2 0 0 2 2 2 1 Ring finger domain zf-RING_UBOX PF13445.6 OQR92449.1 - 0.0002 21.3 7.5 0.00033 20.6 6.6 1.9 1 1 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 OQR92449.1 - 0.00035 20.5 10.7 0.00035 20.5 10.7 2.4 2 0 0 2 2 2 1 zinc-RING finger domain zf-RanBP PF00641.18 OQR92449.1 - 0.00068 18.9 1.6 0.00068 18.9 1.6 2.7 3 0 0 3 3 3 1 Zn-finger in Ran binding protein and others zf-ANAPC11 PF12861.7 OQR92449.1 - 0.0021 18.1 5.7 0.0021 18.1 5.7 1.9 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.6 OQR92449.1 - 0.0033 17.5 8.8 0.0033 17.5 8.8 2.1 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.6 OQR92449.1 - 0.017 14.9 13.1 0.017 14.9 13.1 2.2 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) ATG16 PF08614.11 OQR92449.1 - 0.031 14.5 1.0 0.075 13.3 1.0 1.6 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) zf-RING_10 PF16685.5 OQR92449.1 - 0.4 10.9 12.0 0.045 13.9 7.1 1.9 2 0 0 2 2 2 0 zinc RING finger of MSL2 DZR PF12773.7 OQR92449.1 - 5.4 7.1 18.3 2 8.5 0.4 3.1 2 1 0 2 2 2 0 Double zinc ribbon ABC_membrane PF00664.23 OQR92450.1 - 5.4e-56 190.3 36.0 8.1e-34 117.5 7.4 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 OQR92450.1 - 7.7e-43 146.3 0.0 5e-25 88.6 0.0 2.4 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 OQR92450.1 - 7.4e-06 25.6 0.0 2.4e-05 23.9 0.0 2.0 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 OQR92450.1 - 0.0047 16.9 0.4 1 9.3 0.1 2.4 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 OQR92450.1 - 0.0093 16.0 0.2 7.3 6.7 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase Glyco_hydro_72 PF03198.14 OQR92451.1 - 6.6e-54 183.3 0.5 9.5e-54 182.8 0.5 1.1 1 0 0 1 1 1 1 Glucanosyltransferase Fringe PF02434.16 OQR92451.1 - 1.8e-06 27.6 0.0 4.6e-06 26.2 0.0 1.6 2 0 0 2 2 2 1 Fringe-like TIMELESS PF04821.14 OQR92452.1 - 2.1e-53 181.4 3.3 2.1e-53 181.4 3.3 2.0 2 1 0 2 2 2 1 Timeless protein TIMELESS_C PF05029.13 OQR92452.1 - 8.3e-09 35.1 0.0 8.3e-09 35.1 0.0 3.5 4 0 0 4 4 4 2 Timeless protein C terminal region FAM176 PF14851.6 OQR92452.1 - 0.004 16.8 2.1 0.004 16.8 2.1 4.2 4 0 0 4 4 4 1 FAM176 family DUF913 PF06025.12 OQR92452.1 - 3.3 6.6 8.4 0.066 12.2 0.7 1.9 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) TSNAXIP1_N PF15739.5 OQR92453.1 - 2.1e-13 50.6 3.5 2.1e-13 50.6 3.5 3.8 2 1 1 3 3 2 1 Translin-associated factor X-interacting N-terminus ALIX_LYPXL_bnd PF13949.6 OQR92453.1 - 0.053 12.8 11.0 0.1 11.9 11.0 1.4 1 0 0 1 1 1 0 ALIX V-shaped domain binding to HIV Phos_pyr_kin PF08543.12 OQR92453.1 - 0.091 12.1 4.9 0.14 11.5 3.9 1.8 2 0 0 2 2 2 0 Phosphomethylpyrimidine kinase Ubiquitin_2 PF14560.6 OQR92453.1 - 0.25 11.8 2.8 0.59 10.6 2.8 1.6 1 0 0 1 1 1 0 Ubiquitin-like domain Phe_hydrox_dim PF07976.12 OQR92453.1 - 0.31 11.1 1.5 0.74 9.8 1.5 1.6 1 1 0 1 1 1 0 Phenol hydroxylase, C-terminal dimerisation domain TACC_C PF05010.14 OQR92453.1 - 0.64 9.8 19.8 0.18 11.6 11.2 2.6 1 1 1 2 2 2 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal Syntaxin-6_N PF09177.11 OQR92453.1 - 1.1 9.9 9.9 2.3e+02 2.4 9.2 2.7 1 1 0 1 1 1 0 Syntaxin 6, N-terminal DivIC PF04977.15 OQR92453.1 - 1.8 8.4 7.5 11 5.8 0.1 3.3 2 2 0 2 2 2 0 Septum formation initiator CENP-F_leu_zip PF10473.9 OQR92453.1 - 3.7 7.6 20.0 27 4.8 2.6 2.9 2 1 2 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Tox-REase-5 PF15648.6 OQR92453.1 - 6.2 7.4 6.2 15 6.2 0.0 3.1 2 1 1 3 3 3 0 Restriction endonuclease fold toxin 5 FlaC_arch PF05377.11 OQR92453.1 - 8.2 6.9 12.1 0.52 10.7 0.1 4.3 4 1 1 5 5 5 0 Flagella accessory protein C (FlaC) zf-RING_2 PF13639.6 OQR92454.1 - 1.7e-12 47.5 7.4 1.7e-12 47.5 7.4 2.2 2 0 0 2 2 2 1 Ring finger domain PX PF00787.24 OQR92454.1 - 6.2e-09 35.8 0.1 1.5e-08 34.6 0.1 1.6 1 1 0 1 1 1 1 PX domain zf-RING_UBOX PF13445.6 OQR92454.1 - 8.9e-09 35.2 4.5 2.8e-08 33.7 4.5 1.9 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_11 PF17123.5 OQR92454.1 - 2.4e-07 30.4 5.3 8.1e-07 28.7 5.3 2.0 1 0 0 1 1 1 1 RING-like zinc finger zf-rbx1 PF12678.7 OQR92454.1 - 4.8e-07 30.0 9.7 4.8e-07 30.0 9.7 2.0 2 1 0 2 2 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 OQR92454.1 - 1.7e-06 27.8 9.2 6.3e-06 25.9 9.2 2.0 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 OQR92454.1 - 7e-06 25.8 5.9 7e-06 25.8 5.9 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OQR92454.1 - 8.2e-06 25.7 5.1 8.2e-06 25.7 5.1 2.0 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4 PF00097.25 OQR92454.1 - 6.5e-05 22.7 6.0 6.5e-05 22.7 6.0 1.8 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.8 OQR92454.1 - 0.00077 19.6 5.6 0.00077 19.6 5.6 2.5 2 1 0 2 2 2 1 FANCL C-terminal domain zf-ANAPC11 PF12861.7 OQR92454.1 - 0.00079 19.4 6.3 0.0015 18.6 5.7 1.8 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.6 OQR92454.1 - 0.0021 17.9 4.8 0.0021 17.9 4.8 2.5 2 1 0 2 2 2 1 Prokaryotic RING finger family 4 RINGv PF12906.7 OQR92454.1 - 0.017 15.2 4.2 0.055 13.6 4.2 1.9 1 1 0 1 1 1 0 RING-variant domain DUF1644 PF07800.12 OQR92454.1 - 0.15 12.1 2.9 0.87 9.6 1.2 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1644) zf-Nse PF11789.8 OQR92454.1 - 1.4 8.8 9.7 2.3 8.1 4.2 2.5 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4_4 PF15227.6 OQR92454.1 - 3.6 7.8 10.2 0.66 10.2 4.7 2.6 2 1 0 2 2 2 0 zinc finger of C3HC4-type, RING Zn_ribbon_17 PF17120.5 OQR92454.1 - 9 6.0 16.3 0.29 10.8 9.6 2.0 2 1 0 2 2 1 0 Zinc-ribbon, C4HC2 type zf-RING_2 PF13639.6 OQR92455.1 - 9.3e-14 51.5 4.3 9.3e-14 51.5 4.3 1.9 2 0 0 2 2 1 1 Ring finger domain zf-rbx1 PF12678.7 OQR92455.1 - 3.4e-10 40.0 6.6 1.3e-09 38.2 6.6 1.9 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 OQR92455.1 - 4.3e-10 39.3 5.9 1.4e-09 37.6 5.9 1.9 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 OQR92455.1 - 1.9e-08 34.0 3.4 4e-08 33.0 3.4 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 OQR92455.1 - 4.1e-08 32.8 1.9 1.3e-07 31.2 1.9 1.9 1 1 0 1 1 1 1 RING-like zinc finger zf-C3HC4_3 PF13920.6 OQR92455.1 - 8.7e-08 31.9 3.6 1.9e-07 30.8 3.6 1.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OQR92455.1 - 8.5e-07 28.9 3.8 8.5e-07 28.9 3.8 1.9 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 OQR92455.1 - 2.9e-06 27.1 2.9 6.1e-06 26.1 2.9 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 OQR92455.1 - 8.9e-05 22.5 4.1 0.00018 21.5 2.9 2.0 2 1 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.6 OQR92455.1 - 0.00063 19.5 5.4 0.0036 17.1 4.6 2.4 2 1 1 3 3 3 1 Prokaryotic RING finger family 4 zf-C3H2C3 PF17122.5 OQR92455.1 - 0.00092 19.2 2.7 0.0028 17.7 2.7 1.8 1 0 0 1 1 1 1 Zinc-finger PX PF00787.24 OQR92455.1 - 0.0013 18.7 0.7 0.0022 17.9 0.7 1.4 1 1 0 1 1 1 1 PX domain Zn_ribbon_17 PF17120.5 OQR92455.1 - 0.0024 17.5 5.7 0.0053 16.4 5.7 1.6 1 1 0 1 1 1 1 Zinc-ribbon, C4HC2 type FANCL_C PF11793.8 OQR92455.1 - 0.0037 17.4 6.7 0.0067 16.6 4.3 2.3 2 1 0 2 2 1 1 FANCL C-terminal domain Prok-RING_1 PF14446.6 OQR92455.1 - 0.022 14.7 4.4 0.12 12.3 1.2 2.3 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 zf-RING_4 PF14570.6 OQR92455.1 - 0.054 13.3 1.3 0.12 12.2 1.3 1.6 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain RINGv PF12906.7 OQR92455.1 - 0.079 13.1 4.3 0.24 11.5 4.3 1.8 1 1 0 1 1 1 0 RING-variant domain PHD PF00628.29 OQR92455.1 - 0.084 12.8 3.8 0.15 12.0 3.8 1.5 1 0 0 1 1 1 0 PHD-finger Baculo_RING PF05883.11 OQR92455.1 - 0.089 12.8 0.2 0.17 11.9 0.2 1.5 1 0 0 1 1 1 0 Baculovirus U-box/Ring-like domain zf-RING_10 PF16685.5 OQR92455.1 - 0.095 12.8 2.9 0.26 11.5 2.9 1.8 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-Nse PF11789.8 OQR92455.1 - 0.11 12.3 2.7 0.3 10.9 1.6 2.2 2 1 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit AFG1_ATPase PF03969.16 OQR92455.1 - 0.14 11.1 0.0 0.21 10.4 0.0 1.3 1 0 0 1 1 1 0 AFG1-like ATPase zf-RING-like PF08746.11 OQR92455.1 - 0.23 11.8 3.3 0.6 10.5 3.3 1.7 1 0 0 1 1 1 0 RING-like domain zf-C3HC4_4 PF15227.6 OQR92455.1 - 0.23 11.7 4.7 1.7 8.9 4.8 2.3 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING RecR PF02132.15 OQR92455.1 - 0.83 9.3 5.7 8.5 6.0 0.5 2.4 2 0 0 2 2 2 0 RecR protein RPN6_N PF18055.1 OQR92466.1 - 0.13 12.6 0.0 12 6.3 0.0 2.1 2 0 0 2 2 2 0 26S proteasome regulatory subunit RPN6 N-terminal domain PDDEXK_1 PF12705.7 OQR92467.1 - 5.6e-28 98.5 0.0 1.3e-27 97.4 0.0 1.7 1 0 0 1 1 1 1 PD-(D/E)XK nuclease superfamily UvrD_C PF13361.6 OQR92467.1 - 6.7e-11 42.2 0.5 1.2e-09 38.1 1.7 2.0 1 1 0 2 2 2 1 UvrD-like helicase C-terminal domain Cas_Cas4 PF01930.17 OQR92467.1 - 1.3e-06 28.6 0.0 0.001 19.2 0.0 2.6 2 0 0 2 2 2 2 Domain of unknown function DUF83 AAA_22 PF13401.6 OQR92467.1 - 0.00014 22.1 0.1 1 9.6 0.0 3.3 2 0 0 2 2 2 2 AAA domain Dna2 PF08696.11 OQR92467.1 - 0.0047 16.8 0.0 0.012 15.4 0.0 1.7 1 0 0 1 1 1 1 DNA replication factor Dna2 UPRTase PF14681.6 OQR92467.1 - 0.0055 16.2 0.2 0.011 15.2 0.2 1.4 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase AAA_16 PF13191.6 OQR92467.1 - 1.1 9.6 6.9 1.1 9.6 1.0 3.7 2 2 0 2 2 2 0 AAA ATPase domain polyprenyl_synt PF00348.17 OQR92468.1 - 1.1e-65 221.2 0.1 1.4e-65 220.9 0.1 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase HEPPP_synt_1 PF07307.11 OQR92468.1 - 0.02 14.5 0.1 0.033 13.8 0.1 1.3 1 0 0 1 1 1 0 Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1 Svs_4_5_6 PF17381.2 OQR92468.1 - 0.034 15.1 0.0 0.067 14.2 0.0 1.4 1 0 0 1 1 1 0 Seminal vesicle secretory proteins 4/5/6 KR PF08659.10 OQR92468.1 - 0.084 12.8 0.1 0.14 12.1 0.1 1.3 1 0 0 1 1 1 0 KR domain VirK PF06903.12 OQR92468.1 - 0.13 12.3 0.0 0.25 11.4 0.0 1.4 1 0 0 1 1 1 0 VirK protein Ank_2 PF12796.7 OQR92469.1 - 1.7e-23 83.0 6.6 1.5e-09 38.3 1.0 3.5 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQR92469.1 - 1.4e-17 63.8 3.5 2.8e-08 34.2 0.1 4.7 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQR92469.1 - 2.7e-17 61.1 6.2 0.0057 17.1 0.0 6.8 7 0 0 7 7 7 4 Ankyrin repeat Ank PF00023.30 OQR92469.1 - 3.2e-12 46.3 11.9 0.019 15.4 0.4 6.2 6 0 0 6 6 6 4 Ankyrin repeat Ank_5 PF13857.6 OQR92469.1 - 1.2e-11 44.6 5.1 0.00085 19.6 0.1 5.3 3 1 2 5 5 5 4 Ankyrin repeats (many copies) Shigella_OspC PF06128.11 OQR92469.1 - 0.029 14.1 0.1 1.5 8.5 0.0 2.9 2 1 2 4 4 4 0 Shigella flexneri OspC protein KdpD PF02702.17 OQR92469.1 - 0.049 13.1 0.5 0.19 11.1 0.0 2.1 2 0 0 2 2 2 0 Osmosensitive K+ channel His kinase sensor domain RGS PF00615.19 OQR92469.1 - 0.12 12.7 0.3 17 5.7 0.0 3.2 3 1 1 4 4 4 0 Regulator of G protein signaling domain FbpA PF05833.11 OQR92482.1 - 5.3e-35 121.1 9.7 5.3e-35 121.1 9.7 2.5 2 1 0 2 2 2 1 Fibronectin-binding protein A N-terminus (FbpA) NFACT-R_1 PF05670.13 OQR92482.1 - 5e-33 114.0 1.3 1.2e-31 109.6 0.0 3.8 4 0 0 4 4 4 1 NFACT protein RNA binding domain NFACT-C PF11923.8 OQR92482.1 - 1.3e-28 99.0 0.0 1.3e-28 99.0 0.0 3.8 3 0 0 3 3 2 1 NFACT protein C-terminal domain TPR_1 PF00515.28 OQR92482.1 - 1.9e-12 46.5 12.0 0.028 14.3 0.0 7.6 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_2 PF07719.17 OQR92482.1 - 1.4e-10 40.5 8.0 0.11 12.6 0.0 8.5 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_12 PF13424.6 OQR92482.1 - 1.8e-10 40.9 11.7 0.00016 21.9 0.1 4.5 5 0 0 5 5 4 3 Tetratricopeptide repeat TPR_14 PF13428.6 OQR92482.1 - 0.0013 19.4 9.7 1.1e+02 4.0 0.2 8.3 6 1 2 8 8 8 0 Tetratricopeptide repeat TPR_16 PF13432.6 OQR92482.1 - 0.0033 18.0 7.5 1.2 9.9 0.0 5.9 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_19 PF14559.6 OQR92482.1 - 0.004 17.6 21.7 2.9 8.5 0.0 7.2 7 0 0 7 7 6 3 Tetratricopeptide repeat TPR_10 PF13374.6 OQR92482.1 - 0.018 14.9 6.4 1.5 8.8 0.0 5.4 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_7 PF13176.6 OQR92482.1 - 0.021 14.8 0.2 21 5.4 0.0 4.8 5 0 0 5 5 4 0 Tetratricopeptide repeat DUF5590 PF17881.1 OQR92482.1 - 0.067 13.3 0.0 0.24 11.5 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF5590) TPR_9 PF13371.6 OQR92482.1 - 0.069 13.3 0.1 1.1 9.5 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 OQR92482.1 - 0.24 11.7 14.7 56 4.3 0.0 8.5 10 0 0 10 10 8 0 Tetratricopeptide repeat CRISPR_Cse1 PF09481.10 OQR92482.1 - 2.3 7.2 7.5 1.3 8.0 5.0 1.8 2 0 0 2 2 2 0 CRISPR-associated protein Cse1 (CRISPR_cse1) HATPase_c_3 PF13589.6 OQR92483.1 - 0.052 13.4 0.1 0.14 12.0 0.1 1.7 1 1 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DnaJ PF00226.31 OQR92484.1 - 1.4e-19 70.0 1.1 3.2e-19 68.8 0.4 2.0 2 0 0 2 2 2 1 DnaJ domain Lipase_3 PF01764.25 OQR92484.1 - 0.0037 17.1 0.0 4.1 7.3 0.0 2.8 2 0 0 2 2 2 2 Lipase (class 3) DUF3482 PF11981.8 OQR92484.1 - 2.4 7.5 9.4 5.7 6.2 0.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3482) Fis1_TPR_C PF14853.6 OQR92485.1 - 0.0092 16.0 0.2 0.015 15.4 0.2 1.4 1 0 0 1 1 1 1 Fis1 C-terminal tetratricopeptide repeat BUD22 PF09073.10 OQR92485.1 - 0.024 14.0 3.9 0.032 13.6 3.9 1.1 1 0 0 1 1 1 0 BUD22 NOA36 PF06524.12 OQR92485.1 - 1.1 8.6 6.0 1.3 8.3 6.0 1.1 1 0 0 1 1 1 0 NOA36 protein zf-CW PF07496.15 OQR92489.1 - 4e-47 158.0 39.1 3.1e-17 62.3 9.2 3.6 3 0 0 3 3 3 3 CW-type Zinc Finger DapB_C PF05173.14 OQR92489.1 - 0.0038 17.2 0.1 0.5 10.4 0.0 2.7 2 0 0 2 2 2 2 Dihydrodipicolinate reductase, C-terminus OxoGdeHyase_C PF16870.5 OQR92489.1 - 0.025 14.3 0.1 0.076 12.7 0.1 1.8 1 0 0 1 1 1 0 2-oxoglutarate dehydrogenase C-terminal FmiP_Thoc5 PF09766.9 OQR92509.1 - 5.9e-68 229.8 0.2 5.9e-68 229.8 0.2 2.2 2 0 0 2 2 2 1 Fms-interacting protein/Thoc5 RGI1 PF10843.8 OQR92509.1 - 0.038 13.6 0.4 0.094 12.4 0.4 1.6 1 0 0 1 1 1 0 Respiratory growth induced protein 1 YbfN PF13982.6 OQR92509.1 - 0.088 13.1 0.5 0.35 11.2 0.2 2.1 2 0 0 2 2 2 0 YbfN-like lipoprotein DUF1664 PF07889.12 OQR92509.1 - 2.1 8.4 9.0 8.2 6.5 3.7 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Pkinase PF00069.25 OQR92510.1 - 6.4e-65 219.1 0.0 1.6e-64 217.8 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQR92510.1 - 2.8e-29 102.2 0.0 1.3e-26 93.5 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OQR92510.1 - 2.5e-09 36.9 0.0 3.9e-09 36.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 OQR92510.1 - 8.3e-06 24.8 0.0 1.3e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 OQR92510.1 - 0.03 14.3 0.1 4.3 7.2 0.2 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.14 OQR92510.1 - 0.12 11.8 0.1 0.19 11.1 0.1 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family KRAB PF01352.27 OQR92510.1 - 0.14 11.9 0.0 0.3 10.8 0.0 1.5 1 0 0 1 1 1 0 KRAB box HECT PF00632.25 OQR92511.1 - 2.1e-76 257.3 0.0 2.5e-76 257.1 0.0 1.0 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Pkinase PF00069.25 OQR92527.1 - 4.1e-39 134.5 0.0 1.8e-38 132.5 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQR92527.1 - 1.7e-34 119.3 0.0 2.4e-33 115.5 0.0 2.3 1 1 0 1 1 1 1 Protein tyrosine kinase EphA2_TM PF14575.6 OQR92527.1 - 4.1e-05 24.4 0.0 0.0001 23.1 0.0 1.7 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain Shisa PF13908.6 OQR92527.1 - 0.0017 18.6 0.6 0.0032 17.8 0.6 1.3 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator Pkinase_fungal PF17667.1 OQR92527.1 - 0.0021 16.9 0.0 0.0033 16.3 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase T4SS_CagC PF16943.5 OQR92527.1 - 0.004 17.3 0.4 0.009 16.2 0.4 1.5 1 0 0 1 1 1 1 Cag pathogenicity island, type IV secretory system DUF4307 PF14155.6 OQR92527.1 - 0.0096 15.7 0.0 0.019 14.8 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4307) Adeno_E3_CR2 PF02439.15 OQR92527.1 - 0.018 14.8 3.4 0.045 13.5 3.4 1.6 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 TMEM154 PF15102.6 OQR92527.1 - 0.021 14.7 0.1 0.038 13.9 0.1 1.4 1 0 0 1 1 1 0 TMEM154 protein family ECSCR PF15820.5 OQR92527.1 - 0.037 13.9 0.1 0.083 12.7 0.1 1.6 1 0 0 1 1 1 0 Endothelial cell-specific chemotaxis regulator TMEM51 PF15345.6 OQR92527.1 - 0.042 13.7 0.0 0.071 12.9 0.0 1.3 1 0 0 1 1 1 0 Transmembrane protein 51 MtrF PF09472.10 OQR92527.1 - 6.6 6.2 7.4 0.59 9.6 2.2 1.9 2 0 0 2 2 2 0 Tetrahydromethanopterin S-methyltransferase, F subunit (MtrF) Thaumatin PF00314.17 OQR92529.1 - 8.6e-05 22.3 4.9 0.0048 16.6 1.4 3.0 1 1 1 2 2 2 2 Thaumatin family TPR_12 PF13424.6 OQR92530.1 - 3.3e-31 107.4 0.8 2.3e-14 53.4 0.0 5.5 2 1 4 6 6 6 6 Tetratricopeptide repeat TPR_10 PF13374.6 OQR92530.1 - 6.9e-29 98.9 0.0 7.4e-08 32.0 0.0 6.8 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_2 PF07719.17 OQR92530.1 - 3e-10 39.4 4.9 0.082 13.1 0.0 6.2 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_1 PF00515.28 OQR92530.1 - 2.6e-08 33.3 4.7 0.35 10.8 0.1 5.4 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_8 PF13181.6 OQR92530.1 - 6.7e-07 29.0 2.4 4.1 7.9 0.1 6.2 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_7 PF13176.6 OQR92530.1 - 3e-05 23.7 2.7 3.2 8.0 0.0 5.5 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_17 PF13431.6 OQR92530.1 - 0.049 14.0 3.2 11 6.6 0.1 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat CPSase_L_D2 PF02786.17 OQR92531.1 - 2.1e-74 249.6 0.2 4.1e-74 248.6 0.2 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain PYC_OADA PF02436.18 OQR92531.1 - 8.6e-68 228.0 0.0 1.4e-67 227.3 0.0 1.4 1 0 0 1 1 1 1 Conserved carboxylase domain Biotin_carb_N PF00289.22 OQR92531.1 - 1.6e-39 134.8 0.1 5.6e-39 133.1 0.0 2.1 2 0 0 2 2 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 OQR92531.1 - 7.4e-31 106.4 0.0 2.7e-30 104.6 0.0 2.1 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain HMGL-like PF00682.19 OQR92531.1 - 8.5e-27 94.4 0.0 1.7e-26 93.4 0.0 1.4 1 0 0 1 1 1 1 HMGL-like Biotin_lipoyl PF00364.22 OQR92531.1 - 5e-17 61.5 5.7 1.3e-16 60.2 5.7 1.7 1 0 0 1 1 1 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.13 OQR92531.1 - 8.7e-11 41.7 0.0 2.2e-10 40.4 0.0 1.6 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus Biotin_lipoyl_2 PF13533.6 OQR92531.1 - 6.9e-09 35.4 2.3 0.00034 20.4 0.1 2.7 1 1 1 2 2 2 2 Biotin-lipoyl like ATP-grasp PF02222.22 OQR92531.1 - 1.6e-06 27.8 0.1 6e-06 25.9 0.1 1.9 2 0 0 2 2 2 1 ATP-grasp domain ATP-grasp_3 PF02655.14 OQR92531.1 - 3.4e-05 23.9 0.0 7.6e-05 22.8 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain HlyD_3 PF13437.6 OQR92531.1 - 5.1e-05 23.9 1.0 0.14 12.8 0.1 2.9 2 0 0 2 2 2 2 HlyD family secretion protein HlyD_D23 PF16576.5 OQR92531.1 - 0.00025 20.4 0.9 0.14 11.4 0.1 2.3 1 1 1 2 2 2 2 Barrel-sandwich domain of CusB or HlyD membrane-fusion ATP-grasp_4 PF13535.6 OQR92531.1 - 0.0015 18.1 0.0 0.0035 17.0 0.0 1.7 1 0 0 1 1 1 1 ATP-grasp domain NQRA PF05896.11 OQR92531.1 - 0.0072 15.8 0.9 0.013 15.0 0.9 1.4 1 0 0 1 1 1 1 Na(+)-translocating NADH-quinone reductase subunit A (NQRA) ATPgrasp_ST PF14397.6 OQR92531.1 - 0.011 14.9 0.0 0.089 12.0 0.0 2.3 2 0 0 2 2 2 0 Sugar-transfer associated ATP-grasp ATPgrasp_Ter PF15632.6 OQR92531.1 - 0.017 14.9 0.1 0.049 13.4 0.1 1.8 1 0 0 1 1 1 0 ATP-grasp in the biosynthetic pathway with Ter operon RnfC_N PF13375.6 OQR92531.1 - 0.048 13.6 1.0 0.13 12.2 1.0 1.7 1 0 0 1 1 1 0 RnfC Barrel sandwich hybrid domain GCV_H PF01597.19 OQR92531.1 - 0.22 11.4 1.3 0.84 9.5 0.8 2.2 1 1 1 2 2 2 0 Glycine cleavage H-protein Peptidase_C97 PF05903.14 OQR92532.1 - 1e-43 148.7 0.0 1.4e-43 148.3 0.0 1.1 1 0 0 1 1 1 1 PPPDE putative peptidase domain LRAT PF04970.13 OQR92532.1 - 0.077 13.3 0.0 0.13 12.6 0.0 1.4 1 0 0 1 1 1 0 Lecithin retinol acyltransferase EF-hand_6 PF13405.6 OQR92545.1 - 2.7e-10 39.3 8.7 0.0037 17.1 0.2 7.8 9 0 0 9 9 9 4 EF-hand domain EF-hand_7 PF13499.6 OQR92545.1 - 9e-10 38.9 1.1 0.00018 21.9 0.0 5.1 4 0 0 4 4 4 2 EF-hand domain pair EF-hand_8 PF13833.6 OQR92545.1 - 3.2e-05 23.7 1.1 2.2 8.2 0.1 4.3 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_1 PF00036.32 OQR92545.1 - 0.00037 19.8 4.1 0.18 11.4 0.1 5.0 4 0 0 4 4 4 1 EF hand RIIa PF02197.17 OQR92545.1 - 0.024 14.3 0.0 0.069 12.8 0.0 1.8 1 0 0 1 1 1 0 Regulatory subunit of type II PKA R-subunit EF-hand_5 PF13202.6 OQR92545.1 - 0.04 13.4 2.0 0.61 9.7 0.1 3.7 4 0 0 4 4 4 0 EF hand LMBR1 PF04791.16 OQR92546.1 - 5.5e-41 141.0 34.4 1.5e-23 83.6 7.9 2.0 1 1 1 2 2 2 2 LMBR1-like membrane protein TMEM43 PF07787.12 OQR92546.1 - 0.58 9.5 2.6 0.65 9.3 0.1 2.3 2 0 0 2 2 2 0 Transmembrane protein 43 Toxin_24 PF08094.11 OQR92547.1 - 0.056 13.3 1.4 0.09 12.6 1.4 1.3 1 0 0 1 1 1 0 Conotoxin TVIIA/GS family Cyt-b5 PF00173.28 OQR92554.1 - 8.2e-24 83.6 0.1 9e-12 45.0 0.0 2.2 2 0 0 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain DUF572 PF04502.13 OQR92555.1 - 2.1e-46 159.1 0.2 6.5e-45 154.2 0.2 2.0 1 1 0 1 1 1 1 Family of unknown function (DUF572) SelR PF01641.18 OQR92555.1 - 0.018 15.1 0.6 0.082 13.0 0.1 2.1 1 1 1 2 2 2 0 SelR domain UPF0449 PF15136.6 OQR92555.1 - 0.65 10.5 2.9 0.29 11.6 0.5 1.7 2 0 0 2 2 2 0 Uncharacterised protein family UPF0449 Ribosomal_L26 PF16906.5 OQR92556.1 - 5.8e-17 61.9 1.1 2.2e-16 60.1 1.1 2.1 1 0 0 1 1 1 1 Ribosomal proteins L26 eukaryotic, L24P archaeal C2-C2_1 PF11618.8 OQR92556.1 - 6.8e-07 29.5 2.7 0.00017 21.7 0.3 3.2 2 0 0 2 2 2 2 First C2 domain of RPGR-interacting protein 1 KOW PF00467.29 OQR92556.1 - 1.6e-05 24.7 0.4 3.6e-05 23.5 0.4 1.6 1 0 0 1 1 1 1 KOW motif Fez1 PF06818.15 OQR92556.1 - 0.003 18.0 14.7 0.003 18.0 14.7 3.6 2 1 1 3 3 3 1 Fez1 Rad9 PF04139.13 OQR92556.1 - 0.056 12.9 9.1 0.2 11.1 8.0 2.4 1 1 1 2 2 2 0 Rad9 SnoaL_4 PF13577.6 OQR92557.1 - 1.3e-10 41.5 0.0 1.7e-10 41.1 0.0 1.2 1 0 0 1 1 1 1 SnoaL-like domain SnoaL_2 PF12680.7 OQR92557.1 - 0.00013 22.6 0.0 0.00023 21.8 0.0 1.5 1 1 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.6 OQR92557.1 - 0.023 15.1 0.0 0.03 14.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4440) TPR_2 PF07719.17 OQR92558.1 - 8.7e-05 22.3 0.1 0.38 11.0 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 OQR92558.1 - 0.00043 20.0 0.2 0.078 12.8 0.1 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 OQR92558.1 - 0.0012 19.1 0.3 0.011 16.0 0.1 2.6 2 1 0 2 2 2 1 Tetratricopeptide repeat SPO22 PF08631.10 OQR92558.1 - 0.019 14.4 1.6 0.05 13.1 0.6 1.8 1 1 1 2 2 2 0 Meiosis protein SPO22/ZIP4 like ANAPC3 PF12895.7 OQR92558.1 - 0.3 11.3 1.3 0.44 10.8 0.4 1.8 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 PI3_PI4_kinase PF00454.27 OQR92559.1 - 9.9e-36 123.8 0.4 7.4e-28 98.0 0.4 2.4 1 1 1 2 2 2 2 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.20 OQR92559.1 - 0.00024 20.6 0.3 0.00044 19.7 0.3 1.3 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) DUF4135 PF13575.6 OQR92559.1 - 0.0049 16.2 0.0 0.0071 15.7 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4135) PhyH PF05721.13 OQR92560.1 - 1.2e-10 42.0 0.0 1.6e-10 41.6 0.0 1.2 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) LRR_9 PF14580.6 OQR92561.1 - 1.2e-15 57.5 3.2 1.2e-15 57.5 3.2 3.0 2 1 1 3 3 3 2 Leucine-rich repeat LRR_4 PF12799.7 OQR92561.1 - 6.7e-14 51.8 34.0 4.8e-05 23.6 8.6 4.8 6 0 0 6 6 6 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 OQR92561.1 - 8.9e-09 35.0 29.5 6.2e-06 25.9 8.7 4.5 3 2 1 4 4 4 2 Leucine rich repeat CTP_transf_1 PF01148.20 OQR92563.1 - 9.2e-39 133.8 29.7 2.1e-38 132.6 24.8 2.4 1 1 1 2 2 2 1 Cytidylyltransferase family DJ-1_PfpI PF01965.24 OQR92590.1 - 6e-28 97.7 0.0 4.9e-19 68.7 0.0 2.0 1 1 1 2 2 2 2 DJ-1/PfpI family TMEM234 PF10639.9 OQR92591.1 - 3.4e-37 127.0 0.5 3.9e-37 126.8 0.5 1.0 1 0 0 1 1 1 1 Putative transmembrane family 234 EamA PF00892.20 OQR92591.1 - 0.0066 16.6 2.8 0.0066 16.6 1.7 1.5 2 0 0 2 2 2 1 EamA-like transporter family V-SNARE_C PF12352.8 OQR92592.1 - 8.8e-16 57.9 2.4 2.3e-15 56.6 2.4 1.8 1 0 0 1 1 1 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.13 OQR92592.1 - 1.2e-08 34.8 1.3 1.1e-07 31.6 0.1 2.4 2 1 0 2 2 2 1 Sec20 Band_7 PF01145.25 OQR92593.1 - 3.9e-36 124.7 4.9 3.9e-36 124.7 4.9 1.9 2 1 0 2 2 2 1 SPFH domain / Band 7 family Band_7_1 PF13421.6 OQR92593.1 - 0.0063 16.2 0.0 0.015 15.1 0.0 1.6 1 1 0 1 1 1 1 SPFH domain-Band 7 family DUF2500 PF10694.9 OQR92593.1 - 0.17 12.4 0.0 0.17 12.4 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2500) HEAT PF02985.22 OQR92594.1 - 6.5e-30 100.6 7.9 0.00014 21.8 0.0 11.8 11 0 0 11 11 11 6 HEAT repeat HEAT_EZ PF13513.6 OQR92594.1 - 1.1e-25 89.7 15.9 1.3e-12 48.0 0.0 10.4 11 1 1 12 12 12 4 HEAT-like repeat HEAT_2 PF13646.6 OQR92594.1 - 2.6e-19 69.4 0.0 0.00021 21.6 0.0 7.6 4 3 4 8 8 8 6 HEAT repeats Vac14_Fab1_bd PF12755.7 OQR92594.1 - 2.3e-13 50.6 0.0 0.0023 18.5 0.1 6.3 5 1 2 7 7 7 3 Vacuolar 14 Fab1-binding region Cnd1 PF12717.7 OQR92594.1 - 6.8e-12 45.7 0.5 0.0037 17.3 0.0 4.3 4 0 0 4 4 4 4 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 OQR92594.1 - 1.3e-09 37.1 3.9 0.0035 16.0 0.0 4.1 3 1 1 4 4 4 3 Adaptin N terminal region MMS19_C PF12460.8 OQR92594.1 - 3.3e-08 33.1 1.2 0.31 10.1 0.0 4.5 3 1 1 4 4 4 3 RNAPII transcription regulator C-terminal IBN_N PF03810.19 OQR92594.1 - 6.4e-07 29.2 0.0 3.3e-06 26.9 0.0 2.3 1 0 0 1 1 1 1 Importin-beta N-terminal domain CLASP_N PF12348.8 OQR92594.1 - 6.6e-06 25.8 0.5 2.3 7.7 0.0 5.2 4 2 1 5 5 5 1 CLASP N terminal Arm PF00514.23 OQR92594.1 - 1.9e-05 24.5 8.4 5.8 7.1 0.0 7.8 9 1 0 9 9 9 1 Armadillo/beta-catenin-like repeat RIX1 PF08167.12 OQR92594.1 - 0.0011 18.8 2.8 0.87 9.3 0.0 4.0 3 1 1 4 4 4 1 rRNA processing/ribosome biogenesis TAF6_C PF07571.13 OQR92594.1 - 0.0017 18.7 0.1 12 6.3 0.0 3.9 3 0 0 3 3 3 0 TAF6 C-terminal HEAT repeat domain ANAPC15 PF15243.6 OQR92594.1 - 0.089 13.2 4.0 0.19 12.2 4.0 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 15 Tti2 PF10521.9 OQR92594.1 - 0.11 12.1 5.2 5.1 6.5 0.0 4.6 4 1 1 5 5 5 0 Tti2 family RTP1_C1 PF10363.9 OQR92594.1 - 0.17 12.1 0.2 74 3.6 0.1 4.5 5 1 0 5 5 5 0 Required for nuclear transport of RNA pol II C-terminus 1 Cnd3 PF12719.7 OQR92594.1 - 0.5 9.5 5.6 5.5 6.1 0.0 3.5 4 1 0 4 4 4 0 Nuclear condensing complex subunits, C-term domain LRR_6 PF13516.6 OQR92595.1 - 4.6e-14 51.2 27.3 0.56 10.4 0.0 11.8 13 0 0 13 13 13 6 Leucine Rich repeat LRR_4 PF12799.7 OQR92595.1 - 2.6e-11 43.6 9.1 1.1 9.8 1.1 8.4 4 3 3 8 8 8 6 Leucine Rich repeats (2 copies) WW PF00397.26 OQR92595.1 - 9.5e-11 41.6 22.3 1.2e-06 28.5 3.2 3.5 3 0 0 3 3 3 3 WW domain IQ PF00612.27 OQR92595.1 - 3.8e-08 32.4 83.8 0.12 12.3 0.2 11.9 11 0 0 11 11 11 7 IQ calmodulin-binding motif zf-B_box PF00643.24 OQR92595.1 - 0.00028 21.0 7.4 0.00078 19.6 7.4 1.8 1 0 0 1 1 1 1 B-box zinc finger CEBP_ZZ PF16366.5 OQR92595.1 - 0.021 15.1 5.8 0.066 13.5 5.8 1.8 1 0 0 1 1 1 0 Cytoplasmic polyadenylation element-binding protein ZZ domain Pkinase PF00069.25 OQR92597.1 - 9e-52 176.0 0.3 2.1e-51 174.8 0.3 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQR92597.1 - 4e-23 82.0 0.2 9.7e-23 80.8 0.1 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 OQR92597.1 - 0.0094 15.3 0.0 0.044 13.1 0.0 2.0 1 1 1 2 2 2 1 Kinase-like APH PF01636.23 OQR92597.1 - 0.025 14.5 0.5 0.18 11.7 0.3 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family Myb_DNA-binding PF00249.31 OQR92598.1 - 2.8e-17 62.6 0.1 1.1e-07 31.9 0.0 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OQR92598.1 - 9.4e-07 29.0 0.2 0.00049 20.3 0.0 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OQR92598.1 - 0.0086 15.9 0.1 4.9 7.1 0.0 2.6 2 0 0 2 2 2 2 Myb DNA-binding like Metallophos_2 PF12850.7 OQR92599.1 - 1.1e-06 29.0 0.0 1.6e-06 28.4 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.28 OQR92599.1 - 1.5e-05 25.6 0.0 2.2e-05 25.1 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_3 PF14582.6 OQR92599.1 - 0.00019 20.9 0.0 0.56 9.5 0.1 2.9 2 1 0 2 2 2 2 Metallophosphoesterase, calcineurin superfamily DNA_pol_E_B PF04042.16 OQR92599.1 - 0.0036 16.7 0.0 0.0083 15.5 0.0 1.6 1 1 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B Pkinase PF00069.25 OQR92600.1 - 1.8e-55 188.2 0.0 2.1e-55 187.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQR92600.1 - 2.4e-29 102.4 0.0 1.9e-28 99.5 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OQR92600.1 - 6.3e-10 38.8 0.0 7.9e-10 38.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 OQR92600.1 - 5.9e-07 28.6 0.0 9e-07 28.0 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 OQR92600.1 - 0.00029 20.2 0.2 0.00059 19.2 0.2 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OQR92600.1 - 0.0041 17.1 0.3 0.0073 16.3 0.3 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 OQR92600.1 - 0.1 12.2 0.3 0.18 11.4 0.1 1.5 2 0 0 2 2 2 0 Choline/ethanolamine kinase FYVE PF01363.21 OQR92602.1 - 5.8e-18 64.8 4.3 9.3e-18 64.1 4.3 1.3 1 0 0 1 1 1 1 FYVE zinc finger PH_6 PF15406.6 OQR92602.1 - 0.00021 21.6 0.0 0.00041 20.6 0.0 1.4 1 0 0 1 1 1 1 Pleckstrin homology domain PH_3 PF14593.6 OQR92602.1 - 0.0092 16.1 0.1 0.018 15.1 0.1 1.5 1 0 0 1 1 1 1 PH domain PH PF00169.29 OQR92602.1 - 0.03 14.8 0.0 0.063 13.8 0.0 1.6 1 1 0 1 1 1 0 PH domain Mcp5_PH PF12814.7 OQR92602.1 - 0.097 12.8 0.0 0.2 11.8 0.0 1.5 1 0 0 1 1 1 0 Meiotic cell cortex C-terminal pleckstrin homology FYVE_2 PF02318.16 OQR92602.1 - 0.69 10.2 9.7 0.068 13.4 3.3 2.3 2 0 0 2 2 2 0 FYVE-type zinc finger Zn-ribbon_8 PF09723.10 OQR92602.1 - 1.1 9.5 7.7 7 6.9 2.9 2.4 1 1 1 2 2 2 0 Zinc ribbon domain DZR PF12773.7 OQR92602.1 - 2.8 8.0 7.8 25 5.0 0.4 2.3 1 1 1 2 2 2 0 Double zinc ribbon GBP PF02263.19 OQR92603.1 - 7.8e-49 166.3 0.0 1.6e-48 165.2 0.0 1.5 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain GBP_C PF02841.14 OQR92603.1 - 5.1e-20 72.1 21.3 1.1e-14 54.5 0.2 2.6 3 0 0 3 3 3 2 Guanylate-binding protein, C-terminal domain PH PF00169.29 OQR92603.1 - 1.9e-09 38.0 0.0 6e-09 36.4 0.0 1.9 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 OQR92603.1 - 0.17 12.3 4.7 0.63 10.5 0.2 3.9 3 1 0 3 3 3 0 Pleckstrin homology domain zf-met PF12874.7 OQR92603.1 - 0.32 11.5 3.3 0.15 12.5 0.5 2.0 2 0 0 2 2 2 0 Zinc-finger of C2H2 type Pro_isomerase PF00160.21 OQR92604.1 - 8.5e-33 113.9 0.0 9.8e-33 113.7 0.0 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DUF1298 PF06974.13 OQR92606.1 - 1.5e-10 41.2 0.0 2.8e-10 40.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1298) WES_acyltransf PF03007.16 OQR92606.1 - 3.1e-07 30.4 0.0 2.9e-06 27.2 0.0 2.2 1 1 0 1 1 1 1 Wax ester synthase-like Acyl-CoA acyltransferase domain Complex1_LYR PF05347.15 OQR92606.1 - 5.4e-06 26.4 2.0 1.7e-05 24.8 2.0 1.9 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Zip PF02535.22 OQR92606.1 - 0.81 8.8 6.9 1.3 8.2 6.9 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter CorA PF01544.18 OQR92641.1 - 4.8e-06 26.1 5.8 5.9e-06 25.8 5.8 1.1 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein cNMP_binding PF00027.29 OQR92642.1 - 1.1e-16 60.6 0.0 2.8e-16 59.4 0.0 1.7 2 0 0 2 2 2 1 Cyclic nucleotide-binding domain PX PF00787.24 OQR92642.1 - 4.3e-08 33.1 0.9 4.3e-08 33.1 0.9 2.0 2 0 0 2 2 2 1 PX domain Peptidase_C25 PF01364.18 OQR92642.1 - 0.00087 18.6 0.0 0.0012 18.2 0.0 1.1 1 0 0 1 1 1 1 Peptidase family C25 UPF0449 PF15136.6 OQR92642.1 - 0.04 14.4 0.3 0.1 13.1 0.3 1.6 1 0 0 1 1 1 0 Uncharacterised protein family UPF0449 DEAD PF00270.29 OQR92643.1 - 7.5e-45 152.8 0.0 1.2e-44 152.1 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OQR92643.1 - 8.7e-27 93.7 0.1 8.5e-26 90.5 0.1 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 OQR92643.1 - 6.6e-06 26.2 0.0 2e-05 24.6 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit GUCT PF08152.12 OQR92643.1 - 0.0074 16.6 0.0 0.032 14.5 0.0 2.1 1 0 0 1 1 1 1 GUCT (NUC152) domain CMS1 PF14617.6 OQR92643.1 - 0.019 14.3 0.0 0.05 12.9 0.0 1.7 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit TPR_12 PF13424.6 OQR92644.1 - 9e-37 125.2 0.3 1.4e-09 38.1 0.0 5.2 2 2 2 5 5 5 5 Tetratricopeptide repeat TPR_10 PF13374.6 OQR92644.1 - 1.4e-30 104.2 4.8 3.2e-06 26.8 0.0 7.4 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_1 PF00515.28 OQR92644.1 - 4.4e-11 42.1 3.5 0.0003 20.5 0.1 5.0 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.17 OQR92644.1 - 6.2e-10 38.4 1.1 0.058 13.5 0.0 5.4 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_8 PF13181.6 OQR92644.1 - 2.6e-07 30.3 4.4 0.013 15.6 0.2 4.2 5 0 0 5 5 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 OQR92644.1 - 3e-06 26.9 6.3 0.046 13.8 0.1 4.8 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_MalT PF17874.1 OQR92644.1 - 5.5e-06 26.0 1.4 0.41 10.0 0.1 3.3 2 1 1 3 3 3 2 MalT-like TPR region TPR_6 PF13174.6 OQR92644.1 - 0.0024 18.4 1.2 4.2 8.2 0.0 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat SNAP PF14938.6 OQR92644.1 - 0.0059 16.1 0.2 3.5 7.0 0.1 2.3 2 0 0 2 2 2 2 Soluble NSF attachment protein, SNAP TPR_11 PF13414.6 OQR92644.1 - 0.01 15.5 2.9 1.2 8.9 0.2 3.8 4 0 0 4 4 4 0 TPR repeat DUF4953 PF16313.5 OQR92644.1 - 0.038 13.2 0.1 0.057 12.6 0.1 1.3 1 0 0 1 1 1 0 Met-zincin 14-3-3 PF00244.20 OQR92644.1 - 0.043 13.3 0.8 1.3 8.5 0.1 2.5 1 1 1 2 2 2 0 14-3-3 protein TPR_16 PF13432.6 OQR92644.1 - 0.051 14.2 0.0 8 7.2 0.0 3.2 2 1 0 2 2 2 0 Tetratricopeptide repeat DUF4404 PF14357.6 OQR92644.1 - 0.068 13.8 0.1 2.2 9.0 0.0 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4404) DUF1368 PF07112.11 OQR92644.1 - 0.13 11.1 0.9 0.2 10.4 0.3 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1368) ANAPC5 PF12862.7 OQR92644.1 - 0.42 10.7 7.7 0.94 9.6 0.2 3.8 2 1 0 3 3 3 0 Anaphase-promoting complex subunit 5 PI3Ka PF00613.20 OQR92662.1 - 2.6e-84 281.2 9.4 4.4e-42 143.6 0.5 2.5 2 0 0 2 2 2 2 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PH PF00169.29 OQR92662.1 - 1.9e-56 189.0 21.4 2.7e-15 56.7 0.1 5.7 6 0 0 6 6 5 4 PH domain PI3_PI4_kinase PF00454.27 OQR92662.1 - 3.4e-51 174.5 0.2 2e-39 136.0 0.0 4.5 3 1 0 3 3 3 2 Phosphatidylinositol 3- and 4-kinase PH_8 PF15409.6 OQR92662.1 - 1.7e-15 57.0 12.0 4.6e-06 26.8 0.0 5.7 5 1 0 5 5 4 3 Pleckstrin homology domain PI3K_C2 PF00792.24 OQR92662.1 - 2.7e-15 56.5 0.0 1.9e-08 34.3 0.0 3.1 2 0 0 2 2 2 2 Phosphoinositide 3-kinase C2 PH_11 PF15413.6 OQR92662.1 - 6.8e-13 49.0 23.8 0.003 18.0 2.7 5.7 4 1 0 4 4 4 4 Pleckstrin homology domain PI3K_rbd PF00794.18 OQR92662.1 - 7.3e-13 48.6 2.3 3.1e-05 24.1 0.1 3.0 2 0 0 2 2 2 2 PI3-kinase family, ras-binding domain PH_4 PF15404.6 OQR92662.1 - 2.8e-07 30.5 4.3 0.016 15.0 0.1 3.5 4 0 0 4 4 3 2 Pleckstrin homology domain PH_9 PF15410.6 OQR92662.1 - 4.6e-07 30.2 12.4 0.02 15.3 0.1 4.7 4 0 0 4 4 4 3 Pleckstrin homology domain DUF3136 PF11334.8 OQR92662.1 - 1.8e-05 24.5 0.1 0.35 10.7 0.0 3.0 3 0 0 3 3 3 2 Protein of unknown function (DUF3136) PH_13 PF16652.5 OQR92662.1 - 7.7e-05 22.6 7.3 0.041 13.7 0.3 4.8 5 0 0 5 5 4 1 Pleckstrin homology domain PH_2 PF08458.10 OQR92662.1 - 0.00032 21.0 5.4 15 6.0 0.0 4.7 4 0 0 4 4 4 0 Plant pleckstrin homology-like region Mcp5_PH PF12814.7 OQR92662.1 - 0.0079 16.3 11.4 1.2 9.2 0.0 4.6 4 0 0 4 4 4 2 Meiotic cell cortex C-terminal pleckstrin homology CDT1 PF08839.11 OQR92662.1 - 0.1 12.9 1.3 0.43 10.9 0.1 2.6 2 0 0 2 2 2 0 DNA replication factor CDT1 like DUF2947 PF11163.8 OQR92662.1 - 0.13 12.2 0.8 1.2 9.0 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2947) TPR_20 PF14561.6 OQR92662.1 - 0.21 12.0 1.2 0.42 11.0 0.1 2.1 2 0 0 2 2 1 0 Tetratricopeptide repeat DUF226 PF02890.14 OQR92662.1 - 0.34 10.9 3.8 0.31 11.1 0.7 2.5 2 0 0 2 2 2 0 Borrelia family of unknown function DUF226 CRM1_C PF08767.11 OQR92662.1 - 0.59 9.2 6.4 1.9 7.6 0.7 2.5 2 0 0 2 2 2 0 CRM1 C terminal ELO PF01151.18 OQR92663.1 - 2.6e-67 227.0 19.2 2.6e-67 227.0 19.2 2.4 2 0 0 2 2 2 1 GNS1/SUR4 family MBOAT PF03062.19 OQR92663.1 - 4.8e-31 108.4 3.5 4.8e-31 108.4 3.5 2.3 2 1 0 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family WD40 PF00400.32 OQR92664.1 - 2e-23 82.2 12.5 2.4e-06 28.1 0.1 6.1 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OQR92664.1 - 2.3e-18 66.2 0.2 0.00041 20.6 0.1 5.3 2 2 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 OQR92664.1 - 0.00041 19.1 1.2 0.053 12.2 0.2 2.1 1 1 1 2 2 2 2 Nucleoporin Nup120/160 WD40_like PF17005.5 OQR92664.1 - 0.00056 19.3 0.1 1.7 7.9 0.0 3.3 3 1 1 4 4 4 2 WD40-like domain Nucleoporin_N PF08801.11 OQR92664.1 - 0.067 11.9 0.1 0.17 10.6 0.1 1.7 1 1 0 1 1 1 0 Nup133 N terminal like VID27 PF08553.10 OQR92664.1 - 0.11 11.5 0.0 0.16 11.0 0.0 1.2 1 0 0 1 1 1 0 VID27 C-terminal WD40-like domain MBOAT PF03062.19 OQR92665.1 - 1.2e-39 136.7 9.4 1.2e-39 136.7 9.4 2.0 1 1 1 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family TauE PF01925.19 OQR92666.1 - 1.4e-21 77.3 29.9 3.8e-12 46.4 18.5 2.3 2 1 0 2 2 2 2 Sulfite exporter TauE/SafE Dynein_C PF18199.1 OQR92667.1 - 6.7e-90 301.4 0.0 1e-89 300.8 0.0 1.2 1 0 0 1 1 1 1 Dynein heavy chain C-terminal domain AAA_lid_11 PF18198.1 OQR92667.1 - 3.4e-56 189.6 0.1 6.3e-56 188.7 0.1 1.4 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain Maf PF02545.14 OQR92667.1 - 2.8e-54 183.4 0.0 8.4e-54 181.9 0.0 1.8 2 0 0 2 2 2 1 Maf-like protein Dynein_heavy PF03028.15 OQR92667.1 - 1.8e-31 108.7 0.1 5.5e-31 107.1 0.0 1.8 2 0 0 2 2 2 1 Dynein heavy chain region D6 P-loop domain DUF3456 PF11938.8 OQR92667.1 - 5.2e-09 36.8 4.8 6.4e-07 30.0 0.9 2.3 1 1 0 2 2 2 2 TLR4 regulator and MIR-interacting MSAP AAA_25 PF13481.6 OQR92669.1 - 0.00019 21.1 0.0 0.00037 20.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.6 OQR92669.1 - 0.00023 21.2 0.0 0.0005 20.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 OQR92669.1 - 0.0011 19.2 0.0 0.0031 17.8 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 OQR92669.1 - 0.0013 19.2 0.0 0.0024 18.3 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain IstB_IS21 PF01695.17 OQR92669.1 - 0.0072 16.1 0.0 0.016 14.9 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein ABC_tran PF00005.27 OQR92669.1 - 0.012 16.1 0.0 0.029 14.9 0.0 1.7 2 0 0 2 2 1 0 ABC transporter AAA_11 PF13086.6 OQR92669.1 - 0.033 14.0 0.0 0.065 13.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 OQR92669.1 - 0.048 13.4 0.0 0.098 12.4 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA_7 PF12775.7 OQR92669.1 - 0.048 13.2 0.0 0.13 11.7 0.0 1.7 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_5 PF07728.14 OQR92669.1 - 0.049 13.6 0.0 0.18 11.8 0.0 1.9 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA PF00004.29 OQR92669.1 - 0.058 13.8 0.0 0.15 12.4 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.12 OQR92669.1 - 0.069 12.4 0.0 0.14 11.4 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin ATPase PF06745.13 OQR92669.1 - 0.07 12.5 0.0 0.15 11.4 0.0 1.6 1 0 0 1 1 1 0 KaiC PhoH PF02562.16 OQR92669.1 - 0.07 12.6 0.0 0.13 11.7 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein AAA_28 PF13521.6 OQR92669.1 - 0.15 12.3 0.0 0.77 10.0 0.0 2.0 2 0 0 2 2 2 0 AAA domain Ephrin_rec_like PF07699.13 OQR92670.1 - 4.1e-42 141.7 93.3 3.6e-07 29.8 4.4 10.0 3 2 6 10 10 10 9 Putative ephrin-receptor like NCD3G PF07562.14 OQR92670.1 - 3.2e-18 65.4 60.2 0.0042 17.0 1.0 9.1 7 2 1 8 8 8 8 Nine Cysteines Domain of family 3 GPCR LRR_8 PF13855.6 OQR92670.1 - 4.1e-13 48.9 22.3 6.2e-09 35.5 5.6 4.4 2 1 0 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 OQR92670.1 - 3e-10 40.2 25.3 0.003 17.9 3.5 4.9 4 0 0 4 4 4 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 OQR92670.1 - 9.1e-05 22.5 26.3 0.023 15.2 0.3 8.5 7 2 0 7 7 7 1 Leucine Rich Repeat TNFR_c6 PF00020.18 OQR92670.1 - 0.00065 20.1 67.1 0.45 11.0 0.3 11.8 5 3 3 11 11 11 6 TNFR/NGFR cysteine-rich region LRR_6 PF13516.6 OQR92670.1 - 0.0021 17.9 15.1 0.91 9.7 0.0 6.1 6 0 0 6 6 6 2 Leucine Rich repeat Ras PF00071.22 OQR92671.1 - 1.9e-35 121.8 0.3 2.3e-35 121.6 0.3 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OQR92671.1 - 4e-26 91.6 0.1 6.1e-26 91.0 0.1 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OQR92671.1 - 8.2e-09 35.1 0.1 1e-08 34.9 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 OQR92671.1 - 5.6e-06 25.9 0.4 7e-06 25.6 0.4 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region DLIC PF05783.11 OQR92671.1 - 0.00013 21.0 0.7 0.0056 15.6 0.0 2.0 1 1 1 2 2 2 2 Dynein light intermediate chain (DLIC) GTP_EFTU PF00009.27 OQR92671.1 - 0.00024 20.7 0.3 0.0017 17.9 0.3 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 OQR92671.1 - 0.0015 18.0 0.1 0.0018 17.7 0.1 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 OQR92671.1 - 0.028 14.5 0.0 0.047 13.8 0.0 1.5 1 1 0 1 1 1 0 50S ribosome-binding GTPase FeoB_N PF02421.18 OQR92671.1 - 0.094 12.2 0.1 2.7 7.5 0.0 2.2 2 0 0 2 2 2 0 Ferrous iron transport protein B G-alpha PF00503.20 OQR92671.1 - 0.16 11.1 0.9 0.75 8.9 0.1 2.2 1 1 2 3 3 3 0 G-protein alpha subunit Peptidase_S41 PF03572.18 OQR92683.1 - 2.4e-14 53.3 0.0 3.5e-14 52.7 0.0 1.2 1 0 0 1 1 1 1 Peptidase family S41 EcKinase PF02958.20 OQR92685.1 - 1e-13 51.2 0.2 3.9e-12 46.1 0.1 2.2 2 1 0 2 2 2 1 Ecdysteroid kinase APH PF01636.23 OQR92685.1 - 4.2e-12 46.5 0.0 6.4e-12 45.9 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.11 OQR92685.1 - 9e-12 44.6 0.1 2.3e-11 43.2 0.1 1.5 1 1 1 2 2 2 1 Protein of unknown function (DUF1679) Choline_kinase PF01633.20 OQR92685.1 - 0.012 15.2 0.0 0.02 14.5 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase EF_assoc_2 PF08356.12 OQR92686.1 - 0.15 12.0 0.1 0.18 11.8 0.1 1.1 1 0 0 1 1 1 0 EF hand associated Peptidase_M3 PF01432.20 OQR92688.1 - 7e-142 473.9 0.0 1.3e-141 473.1 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M3 Peptidase_M50B PF13398.6 OQR92688.1 - 0.014 15.0 0.0 0.025 14.2 0.0 1.3 1 0 0 1 1 1 0 Peptidase M50B-like PhaP_Bmeg PF09602.10 OQR92688.1 - 0.056 13.4 1.0 0.79 9.6 0.2 2.9 4 0 0 4 4 4 0 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) HA PF03457.14 OQR92688.1 - 0.086 13.2 0.1 0.2 12.0 0.1 1.6 1 0 0 1 1 1 0 Helicase associated domain ABC_tran_CTD PF16326.5 OQR92688.1 - 0.42 10.9 4.7 1.7 9.0 0.2 3.5 4 0 0 4 4 4 0 ABC transporter C-terminal domain Kinesin PF00225.23 OQR92689.1 - 1.8e-91 306.6 0.2 1.8e-91 306.6 0.2 1.6 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 OQR92689.1 - 2.8e-15 56.5 0.0 8.1e-15 55.0 0.0 1.8 1 0 0 1 1 1 1 Microtubule binding FHA PF00498.26 OQR92689.1 - 1.7e-05 25.0 0.2 0.00015 22.1 0.0 2.5 2 0 0 2 2 2 1 FHA domain DUF3437 PF11919.8 OQR92689.1 - 0.025 14.5 0.4 0.025 14.5 0.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3437) Yop-YscD_cpl PF16697.5 OQR92689.1 - 0.073 13.4 0.0 0.26 11.6 0.0 1.9 1 0 0 1 1 1 0 Inner membrane component of T3SS, cytoplasmic domain Staphostatin_A PF09022.10 OQR92689.1 - 0.1 12.5 0.2 0.27 11.2 0.2 1.7 1 0 0 1 1 1 0 Staphostatin A LMWPc PF01451.21 OQR92691.1 - 2.6e-25 89.5 0.0 4.5e-25 88.7 0.0 1.4 1 0 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase Peptidase_M3 PF01432.20 OQR92694.1 - 1.3e-142 476.3 0.0 1.8e-142 475.8 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M3 Peptidase_M50B PF13398.6 OQR92694.1 - 0.023 14.4 0.0 0.041 13.5 0.0 1.3 1 0 0 1 1 1 0 Peptidase M50B-like FYVE PF01363.21 OQR92728.1 - 9.5e-18 64.1 12.3 1.8e-17 63.2 12.3 1.4 1 0 0 1 1 1 1 FYVE zinc finger GAF PF01590.26 OQR92728.1 - 2.7e-09 37.8 0.0 5.7e-09 36.7 0.0 1.5 1 0 0 1 1 1 1 GAF domain GAF_3 PF13492.6 OQR92728.1 - 0.0029 17.9 0.0 0.0077 16.6 0.0 1.7 1 0 0 1 1 1 1 GAF domain C1_2 PF03107.16 OQR92728.1 - 0.015 15.6 5.5 0.035 14.4 5.5 1.6 1 0 0 1 1 1 0 C1 domain VAD1-2 PF15310.6 OQR92728.1 - 0.1 12.5 3.5 0.17 11.7 3.5 1.3 1 0 0 1 1 1 0 Vitamin A-deficiency (VAD) rat model signalling FYVE_2 PF02318.16 OQR92728.1 - 0.44 10.8 6.9 1.2 9.4 6.9 1.7 1 0 0 1 1 1 0 FYVE-type zinc finger Zf_RING PF16744.5 OQR92728.1 - 1.1 9.4 8.4 3 8.0 8.4 1.7 1 0 0 1 1 1 0 KIAA1045 RING finger Peptidase_M14 PF00246.24 OQR92729.1 - 2.6e-38 132.5 0.2 3.5e-38 132.0 0.2 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase AstE_AspA PF04952.14 OQR92729.1 - 0.00075 18.7 0.0 0.0014 17.8 0.0 1.5 1 1 0 1 1 1 1 Succinylglutamate desuccinylase / Aspartoacylase family VirArc_Nuclease PF12187.8 OQR92729.1 - 0.058 12.9 0.1 0.11 12.1 0.1 1.4 1 0 0 1 1 1 0 Viral/Archaeal nuclease DUF2817 PF10994.8 OQR92729.1 - 0.096 12.1 0.0 0.17 11.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2817) FYVE PF01363.21 OQR92730.1 - 1.1e-15 57.5 17.7 1.1e-15 57.5 17.7 2.2 3 0 0 3 3 3 1 FYVE zinc finger EF-hand_7 PF13499.6 OQR92731.1 - 7.8e-10 39.1 2.1 2.5e-09 37.4 0.3 2.5 2 1 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 OQR92731.1 - 3e-09 36.1 0.2 0.0025 17.6 0.0 4.0 4 0 0 4 4 4 2 EF-hand domain EF-hand_1 PF00036.32 OQR92731.1 - 3e-08 32.6 0.7 0.00033 20.0 0.1 3.6 4 0 0 4 4 4 2 EF hand EF-hand_8 PF13833.6 OQR92731.1 - 7.8e-07 28.9 4.1 0.019 14.8 0.1 3.6 4 0 0 4 4 4 2 EF-hand domain pair EF-hand_5 PF13202.6 OQR92731.1 - 4e-06 26.1 0.1 0.0064 15.9 0.0 3.3 3 0 0 3 3 3 2 EF hand DUF760 PF05542.11 OQR92731.1 - 0.01 16.2 0.0 0.029 14.7 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF760) Nucleopor_Nup85 PF07575.13 OQR92731.1 - 0.11 11.0 0.0 0.15 10.6 0.0 1.1 1 0 0 1 1 1 0 Nup85 Nucleoporin EF-hand_4 PF12763.7 OQR92731.1 - 0.13 12.2 0.1 0.27 11.2 0.1 1.5 1 1 0 1 1 1 0 Cytoskeletal-regulatory complex EF hand Mito_fiss_reg PF05308.11 OQR92731.1 - 1.4 8.9 3.8 2.3 8.2 3.8 1.4 1 0 0 1 1 1 0 Mitochondrial fission regulator Med9 PF07544.13 OQR92732.1 - 2.9e-12 46.5 0.4 3.6e-12 46.2 0.4 1.1 1 0 0 1 1 1 1 RNA polymerase II transcription mediator complex subunit 9 DASH_Duo1 PF08651.10 OQR92732.1 - 0.059 13.1 0.1 0.16 11.8 0.1 1.6 2 0 0 2 2 2 0 DASH complex subunit Duo1 zf-B_box PF00643.24 OQR92733.1 - 2.6e-06 27.5 40.3 0.00038 20.5 4.8 3.6 3 0 0 3 3 3 3 B-box zinc finger Rox3 PF08633.10 OQR92733.1 - 0.026 14.8 0.1 0.026 14.8 0.1 1.9 2 0 0 2 2 2 0 Rox3 mediator complex subunit DUF2431 PF10354.9 OQR92733.1 - 0.069 13.4 0.1 0.069 13.4 0.1 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF2431) APG6_N PF17675.1 OQR92733.1 - 3.1 8.3 16.0 0.068 13.7 3.8 3.1 3 0 0 3 3 3 0 Apg6 coiled-coil region Biotin_lipoyl PF00364.22 OQR92734.1 - 1.7e-15 56.6 0.2 3.2e-15 55.7 0.1 1.5 1 1 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 OQR92734.1 - 6.8e-05 22.6 0.0 0.00015 21.5 0.0 1.6 1 0 0 1 1 1 1 Biotin-lipoyl like FYVE PF01363.21 OQR92735.1 - 2.1e-09 37.4 6.1 2.3e-09 37.3 6.1 1.1 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.16 OQR92735.1 - 0.0093 16.2 1.7 0.0093 16.2 1.7 1.1 1 0 0 1 1 1 1 FYVE-type zinc finger zf-C2HC5 PF06221.13 OQR92735.1 - 0.1 12.6 6.2 0.19 11.7 6.3 1.5 1 1 0 1 1 1 0 Putative zinc finger motif, C2HC5-type DUF2256 PF10013.9 OQR92735.1 - 2.4 8.3 7.3 1.1 9.4 0.3 2.4 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2256) Sigma70_r4 PF04545.16 OQR92746.1 - 0.00036 20.0 0.2 0.00091 18.7 0.2 1.7 1 0 0 1 1 1 1 Sigma-70, region 4 CENP-B_N PF04218.13 OQR92746.1 - 0.00089 18.9 0.2 0.0021 17.6 0.2 1.7 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain HTH_29 PF13551.6 OQR92746.1 - 0.05 13.6 0.1 0.14 12.2 0.1 1.8 1 0 0 1 1 1 0 Winged helix-turn helix HTH_24 PF13412.6 OQR92746.1 - 0.091 12.3 0.0 0.2 11.2 0.0 1.6 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding Ank_2 PF12796.7 OQR92747.1 - 1.2e-23 83.5 12.9 8e-09 36.0 0.6 4.3 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OQR92747.1 - 3.9e-20 71.7 12.8 0.0068 16.7 0.0 7.5 1 1 7 8 8 8 6 Ankyrin repeats (many copies) Ank_4 PF13637.6 OQR92747.1 - 2.3e-19 69.5 11.7 9.3e-05 22.9 0.1 5.9 3 1 2 6 6 6 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQR92747.1 - 1.2e-11 43.7 10.4 1.7 9.4 0.0 8.8 8 1 1 9 9 9 3 Ankyrin repeat DUF5049 PF16468.5 OQR92747.1 - 7.8e-07 28.9 6.6 1.5 8.8 0.0 7.3 1 1 8 9 9 9 1 Domain of unknown function (DUF5049) Ank PF00023.30 OQR92747.1 - 0.00031 21.0 10.7 6.7 7.4 0.1 6.8 3 2 1 4 4 4 2 Ankyrin repeat DUF249 PF03158.13 OQR92747.1 - 0.0013 18.5 5.0 0.52 10.0 0.0 4.2 2 2 3 5 5 5 1 Multigene family 530 protein DUF1707 PF08044.11 OQR92747.1 - 0.05 13.7 1.7 23 5.2 0.0 4.4 5 0 0 5 5 5 0 Domain of unknown function (DUF1707) ENTH PF01417.20 OQR92747.1 - 0.17 11.9 1.0 16 5.5 0.0 3.6 3 2 0 3 3 3 0 ENTH domain YmaF PF12788.7 OQR92747.1 - 4.6 7.8 11.9 15 6.2 2.9 3.4 1 1 3 4 4 4 0 YmaF family CKS PF01111.19 OQR92748.1 - 2.4e-35 120.6 0.7 3.1e-35 120.3 0.7 1.1 1 0 0 1 1 1 1 Cyclin-dependent kinase regulatory subunit Ank_2 PF12796.7 OQR92754.1 - 1.4e-33 115.3 11.1 5.6e-10 39.7 0.1 8.0 3 1 5 8 8 8 5 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OQR92754.1 - 3e-25 87.9 13.4 0.08 13.3 0.0 13.2 4 3 9 13 13 13 5 Ankyrin repeats (many copies) Ank_4 PF13637.6 OQR92754.1 - 2.9e-24 85.1 12.5 2.9e-05 24.5 0.0 10.3 5 3 6 11 11 11 8 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQR92754.1 - 1e-14 53.2 5.6 2.4 9.0 0.0 12.7 12 1 1 13 13 11 1 Ankyrin repeat Methyltransf_11 PF08241.12 OQR92754.1 - 6.4e-12 46.0 0.0 1.7e-11 44.6 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OQR92754.1 - 2.8e-10 40.8 0.1 3e-09 37.5 0.0 2.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 OQR92754.1 - 2.5e-09 37.2 0.0 9.1e-09 35.4 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 OQR92754.1 - 1.4e-08 34.7 0.0 6.8e-08 32.5 0.0 2.2 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_12 PF08242.12 OQR92754.1 - 7.3e-07 29.9 0.0 2.2e-06 28.3 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain TPR_19 PF14559.6 OQR92754.1 - 3.7e-06 27.4 0.0 1.1e-05 25.9 0.0 1.9 1 0 0 1 1 1 1 Tetratricopeptide repeat Thioredoxin_8 PF13905.6 OQR92754.1 - 0.00079 19.7 0.1 0.0022 18.3 0.1 1.7 1 0 0 1 1 1 1 Thioredoxin-like Ank PF00023.30 OQR92754.1 - 0.002 18.5 12.8 6 7.5 0.5 9.0 7 3 0 7 7 6 1 Ankyrin repeat TPR_2 PF07719.17 OQR92754.1 - 0.011 15.8 0.0 1.1 9.6 0.0 3.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_17 PF13431.6 OQR92754.1 - 0.013 15.9 0.1 1.8 9.1 0.0 3.3 3 0 0 3 3 2 0 Tetratricopeptide repeat TPR_9 PF13371.6 OQR92754.1 - 0.015 15.5 0.0 0.036 14.2 0.0 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_11 PF13414.6 OQR92754.1 - 0.016 14.9 0.0 0.14 11.9 0.0 2.5 2 0 0 2 2 2 0 TPR repeat DUF5049 PF16468.5 OQR92754.1 - 0.017 15.0 0.1 11 6.0 0.0 3.9 3 0 0 3 3 2 0 Domain of unknown function (DUF5049) TPR_8 PF13181.6 OQR92754.1 - 0.034 14.3 0.0 0.44 10.9 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat NodS PF05401.11 OQR92754.1 - 0.056 13.1 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 Nodulation protein S (NodS) TPR_1 PF00515.28 OQR92754.1 - 0.069 13.0 0.0 16 5.5 0.0 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat TPPII_N PF12583.8 OQR92754.1 - 0.12 13.0 0.5 2.7 8.6 0.0 3.1 3 1 1 4 4 4 0 Tripeptidyl peptidase II N terminal Homeodomain PF00046.29 OQR92772.1 - 0.085 12.7 0.1 0.34 10.8 0.1 2.1 1 0 0 1 1 1 0 Homeodomain ThiF PF00899.21 OQR92773.1 - 6.8e-90 300.7 0.0 4e-63 213.0 0.0 2.4 1 1 1 2 2 2 2 ThiF family UBA_e1_thiolCys PF10585.9 OQR92773.1 - 1.3e-65 221.8 0.8 1.3e-65 221.8 0.8 1.7 2 0 0 2 2 2 1 Ubiquitin-activating enzyme active site E1_4HB PF16191.5 OQR92773.1 - 9.3e-17 61.0 0.1 6.2e-16 58.3 0.0 2.5 3 0 0 3 3 3 1 Ubiquitin-activating enzyme E1 four-helix bundle E1_FCCH PF16190.5 OQR92773.1 - 9.8e-11 41.7 0.4 8.3e-09 35.5 0.1 3.1 2 1 0 2 2 2 1 Ubiquitin-activating enzyme E1 FCCH domain MORN PF02493.20 OQR92775.1 - 3.7e-17 61.1 30.6 7.7e-06 25.5 0.0 6.5 6 1 0 6 6 6 5 MORN repeat HSP70 PF00012.20 OQR92800.1 - 9.7e-103 344.4 0.0 1.2e-102 344.1 0.0 1.1 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 OQR92800.1 - 1.5e-15 56.8 0.0 2.9e-08 32.9 0.0 3.2 3 0 0 3 3 3 3 MreB/Mbl protein StbA PF06406.11 OQR92800.1 - 0.11 11.7 0.0 0.34 10.1 0.0 1.8 2 0 0 2 2 2 0 StbA protein BcrAD_BadFG PF01869.20 OQR92800.1 - 0.12 11.8 0.0 2.8 7.3 0.0 2.2 2 0 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family Peptidase_A22B PF04258.13 OQR92801.1 - 1.2e-45 156.3 13.8 1.6e-45 155.9 9.5 2.5 2 1 0 2 2 2 1 Signal peptide peptidase PA PF02225.22 OQR92801.1 - 5e-06 26.5 0.0 3.5e-05 23.7 0.0 2.3 2 0 0 2 2 2 1 PA domain CRT-like PF08627.10 OQR92821.1 - 9.2e-12 44.5 3.8 9.7e-12 44.5 3.8 1.0 1 0 0 1 1 1 1 CRT-like, chloroquine-resistance transporter-like BP28CT PF08146.12 OQR92822.1 - 8.2e-30 103.7 0.5 8.2e-30 103.7 0.5 3.1 3 1 0 3 3 3 1 BP28CT (NUC211) domain U3snoRNP10 PF12397.8 OQR92822.1 - 3.8e-22 78.8 0.5 3.8e-22 78.8 0.5 5.8 5 0 0 5 5 5 1 U3 small nucleolar RNA-associated protein 10 HEAT_2 PF13646.6 OQR92822.1 - 4.3e-05 23.8 2.2 0.27 11.6 0.2 4.7 3 0 0 3 3 3 1 HEAT repeats HEAT PF02985.22 OQR92822.1 - 0.00018 21.5 3.0 0.077 13.3 0.2 5.1 4 0 0 4 4 4 1 HEAT repeat ParcG PF10274.9 OQR92822.1 - 0.0016 18.6 3.2 2.1 8.4 0.2 4.7 4 0 0 4 4 4 1 Parkin co-regulated protein YcbB PF08664.10 OQR92822.1 - 0.013 15.5 0.3 0.12 12.4 0.0 2.5 2 0 0 2 2 2 0 YcbB domain DUF2218 PF09981.9 OQR92822.1 - 0.058 13.8 0.6 0.29 11.6 0.6 2.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2218) MSP7_C PF12948.7 OQR92822.1 - 0.071 13.8 0.2 0.19 12.4 0.2 1.7 1 0 0 1 1 1 0 MSP7-like protein C-terminal domain Ribosomal_L22 PF00237.19 OQR92823.1 - 2.7e-26 91.8 0.4 5.2e-26 90.9 0.4 1.5 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e CRT-like PF08627.10 OQR92824.1 - 2.4e-121 404.8 37.4 1.3e-56 192.0 13.4 3.1 3 0 0 3 3 3 3 CRT-like, chloroquine-resistance transporter-like SLC35F PF06027.12 OQR92824.1 - 4.4e-11 42.8 2.6 5.9e-06 26.0 0.3 4.4 4 1 0 4 4 4 2 Solute carrier family 35 UAA PF08449.11 OQR92824.1 - 2e-07 30.6 6.5 0.00062 19.1 3.4 2.8 2 0 0 2 2 2 2 UAA transporter family Nuc_sug_transp PF04142.15 OQR92824.1 - 2.2e-05 23.8 12.1 0.00015 21.0 1.5 3.6 4 0 0 4 4 4 2 Nucleotide-sugar transporter EamA PF00892.20 OQR92824.1 - 0.094 12.9 0.3 0.094 12.9 0.3 6.1 5 3 1 6 6 6 0 EamA-like transporter family CRT-like PF08627.10 OQR92825.1 - 5.9e-09 35.3 0.8 6.3e-09 35.2 0.8 1.0 1 0 0 1 1 1 1 CRT-like, chloroquine-resistance transporter-like SLC35F PF06027.12 OQR92825.1 - 0.0015 18.1 0.1 0.0015 18.1 0.1 1.1 1 0 0 1 1 1 1 Solute carrier family 35 Peptidase_S10 PF00450.22 OQR92826.1 - 1.9e-29 103.4 0.3 2.6e-29 102.9 0.3 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase Homez PF11569.8 OQR92826.1 - 0.088 12.3 0.0 0.16 11.4 0.0 1.4 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez Ribosomal_L22 PF00237.19 OQR92834.1 - 1.5e-33 115.1 0.1 3.8e-33 113.8 0.1 1.7 1 1 0 1 1 1 1 Ribosomal protein L22p/L17e ACP53EA PF06313.11 OQR92835.1 - 0.11 12.7 0.0 0.17 12.1 0.0 1.2 1 0 0 1 1 1 0 Drosophila ACP53EA protein CoA_transf_3 PF02515.17 OQR92837.1 - 0.001 18.3 0.0 0.0039 16.4 0.0 1.8 1 1 0 1 1 1 1 CoA-transferase family III TPH PF13868.6 OQR92839.1 - 2.3e-12 46.1 111.8 2.3e-12 46.1 111.8 2.1 1 1 1 2 2 2 1 Trichohyalin-plectin-homology domain NuA4 PF09340.10 OQR92839.1 - 0.017 15.0 1.8 0.095 12.6 0.0 3.3 2 0 0 2 2 2 0 Histone acetyltransferase subunit NuA4 RCC1 PF00415.18 OQR92840.1 - 1.3e-90 297.9 17.5 9.3e-15 55.0 0.1 7.5 7 0 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 OQR92840.1 - 6.4e-47 156.5 36.6 2.7e-10 39.8 2.5 7.7 7 0 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat ubiquitin PF00240.23 OQR92840.1 - 4.9e-19 67.9 0.1 9.4e-19 66.9 0.1 1.5 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 OQR92840.1 - 3.9e-05 23.4 0.0 6.7e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 OQR92840.1 - 0.00042 20.8 0.0 0.0009 19.8 0.0 1.5 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain Rad60-SLD_2 PF13881.6 OQR92840.1 - 0.00069 19.7 0.0 0.0017 18.4 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Methyltransf_23 PF13489.6 OQR92851.1 - 4.7e-26 91.6 0.0 6.4e-26 91.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OQR92851.1 - 2.1e-20 73.2 0.1 3.4e-20 72.5 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OQR92851.1 - 2.4e-16 60.2 0.1 4.2e-16 59.4 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OQR92851.1 - 6.5e-16 58.5 0.0 8.7e-16 58.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OQR92851.1 - 3.7e-15 56.5 0.1 6.1e-15 55.8 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 OQR92851.1 - 7.7e-11 41.8 0.0 1.2e-10 41.1 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase PrmA PF06325.13 OQR92851.1 - 2.8e-10 40.1 0.0 3.9e-10 39.6 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_9 PF08003.11 OQR92851.1 - 8e-07 28.3 0.0 1.3e-06 27.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) NodS PF05401.11 OQR92851.1 - 2.1e-05 24.2 0.0 2.9e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) MTS PF05175.14 OQR92851.1 - 5.1e-05 22.9 0.1 0.0001 21.9 0.1 1.4 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_16 PF10294.9 OQR92851.1 - 0.00026 20.8 0.0 0.00048 19.9 0.0 1.4 1 0 0 1 1 1 1 Lysine methyltransferase Ubie_methyltran PF01209.18 OQR92851.1 - 0.00037 19.9 0.0 0.00056 19.3 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_PK PF05891.12 OQR92851.1 - 0.00091 18.8 0.0 0.0012 18.4 0.0 1.2 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_32 PF13679.6 OQR92851.1 - 0.0021 18.0 0.0 0.0039 17.2 0.0 1.5 2 0 0 2 2 1 1 Methyltransferase domain TPMT PF05724.11 OQR92851.1 - 0.0025 17.5 0.1 0.014 15.0 0.1 2.0 1 1 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) MetW PF07021.12 OQR92851.1 - 0.0066 16.1 0.0 0.0099 15.5 0.0 1.2 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW TehB PF03848.14 OQR92851.1 - 0.0088 15.5 0.0 0.018 14.5 0.0 1.5 2 0 0 2 2 2 1 Tellurite resistance protein TehB NAD_binding_2 PF03446.15 OQR92851.1 - 0.015 15.4 0.0 0.026 14.7 0.0 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase DREV PF05219.12 OQR92851.1 - 0.017 14.2 0.0 0.024 13.7 0.0 1.2 1 0 0 1 1 1 0 DREV methyltransferase PCMT PF01135.19 OQR92851.1 - 0.084 12.6 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Coatomer_WDAD PF04053.14 OQR92852.1 - 1.7e-124 416.3 0.0 2.6e-124 415.7 0.0 1.3 1 0 0 1 1 1 1 Coatomer WD associated region COPI_C PF06957.11 OQR92852.1 - 5.8e-106 354.6 0.1 9e-106 354.0 0.1 1.2 1 0 0 1 1 1 1 Coatomer (COPI) alpha subunit C-terminus WD40 PF00400.32 OQR92852.1 - 1e-45 152.7 21.1 8.4e-09 35.9 0.3 8.5 8 0 0 8 8 8 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OQR92852.1 - 5e-11 42.7 1.6 8e-05 22.9 0.1 6.1 4 2 3 7 7 7 2 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 OQR92852.1 - 0.021 14.7 0.2 6.8 6.5 0.0 3.2 3 0 0 3 3 3 0 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 OQR92852.1 - 0.25 9.9 7.0 1.7 7.2 0.1 3.3 2 1 1 3 3 3 0 Nucleoporin Nup120/160 PA PF02225.22 OQR92853.1 - 9.6e-11 41.6 0.0 0.00014 21.8 0.0 2.8 2 1 0 2 2 2 2 PA domain PDZ_6 PF17820.1 OQR92853.1 - 2.5e-05 24.0 0.0 5.8e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 OQR92853.1 - 0.00085 19.6 0.0 0.002 18.5 0.0 1.6 1 0 0 1 1 1 1 PDZ domain zf-RING_4 PF14570.6 OQR92854.1 - 8.5e-21 73.5 10.9 1.7e-20 72.5 10.9 1.6 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain RRM_1 PF00076.22 OQR92854.1 - 5e-08 32.7 0.0 1.1e-07 31.6 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-C3HC4_3 PF13920.6 OQR92854.1 - 4.4e-07 29.7 9.7 8.6e-07 28.7 9.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-UDP PF14569.6 OQR92854.1 - 0.00035 20.6 4.9 0.00098 19.2 4.9 1.7 1 0 0 1 1 1 1 Zinc-binding RING-finger zf-RING_2 PF13639.6 OQR92854.1 - 0.0074 16.6 13.3 0.015 15.6 13.3 1.5 1 0 0 1 1 1 1 Ring finger domain Torus PF16131.5 OQR92854.1 - 0.062 14.0 0.1 0.062 14.0 0.1 2.0 2 0 0 2 2 1 0 Torus domain zf-CCCH_2 PF14608.6 OQR92854.1 - 0.087 13.3 2.1 0.3 11.6 2.1 2.0 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger Nup35_RRM_2 PF14605.6 OQR92854.1 - 0.13 12.3 0.0 0.39 10.8 0.0 1.8 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif Prok-RING_4 PF14447.6 OQR92854.1 - 0.14 12.1 9.9 1.7 8.6 7.8 2.5 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 Rad50_zn_hook PF04423.14 OQR92854.1 - 0.34 10.8 3.4 0.38 10.6 0.7 2.3 2 0 0 2 2 2 0 Rad50 zinc hook motif DUF2486 PF10667.9 OQR92854.1 - 0.36 11.0 12.7 0.59 10.3 12.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2486) DZR PF12773.7 OQR92854.1 - 1.8 8.7 10.3 0.23 11.5 0.7 2.5 2 0 0 2 2 2 0 Double zinc ribbon FYVE_2 PF02318.16 OQR92854.1 - 2.1 8.6 11.9 1.3 9.2 9.9 1.7 1 1 0 1 1 1 0 FYVE-type zinc finger Baculo_IE-1 PF05290.11 OQR92854.1 - 3.4 7.6 8.6 3.9 7.4 7.3 1.7 2 0 0 2 2 2 0 Baculovirus immediate-early protein (IE-0) PX PF00787.24 OQR92889.1 - 8.5e-09 35.4 0.2 8.3e-08 32.2 0.1 2.1 2 0 0 2 2 2 1 PX domain zf-RING_2 PF13639.6 OQR92889.1 - 4.1e-08 33.4 19.4 4.1e-08 33.4 19.4 2.0 2 0 0 2 2 2 1 Ring finger domain zf-RING_11 PF17123.5 OQR92889.1 - 2e-06 27.5 12.0 2e-06 27.5 12.0 2.0 2 0 0 2 2 2 1 RING-like zinc finger zf-rbx1 PF12678.7 OQR92889.1 - 0.0001 22.5 17.5 0.0001 22.5 17.5 2.4 2 1 0 2 2 2 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 OQR92889.1 - 0.0017 18.4 11.0 0.0017 18.4 11.0 2.2 2 1 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_2 PF13923.6 OQR92889.1 - 0.0068 16.2 18.5 0.031 14.1 18.5 2.2 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OQR92889.1 - 0.0085 16.1 15.9 0.0085 16.1 15.9 2.0 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 OQR92889.1 - 0.064 13.2 16.5 0.18 11.8 16.5 1.8 1 0 0 1 1 1 0 zinc-RING finger domain FANCL_C PF11793.8 OQR92889.1 - 0.067 13.4 11.3 0.23 11.7 11.3 2.0 1 1 0 1 1 1 0 FANCL C-terminal domain EB PF01683.18 OQR92890.1 - 0.26 11.6 18.3 0.11 12.8 9.5 3.0 2 1 0 2 2 2 0 EB module MFS_1 PF07690.16 OQR92891.1 - 1e-32 113.5 35.8 1e-32 113.5 35.8 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily Glyco_hydro_17 PF00332.18 OQR92894.1 - 0.041 13.5 0.2 0.079 12.5 0.2 1.7 1 1 0 1 1 1 0 Glycosyl hydrolases family 17 Laminin_II PF06009.12 OQR92895.1 - 0.14 12.2 3.0 2 8.4 0.0 2.7 2 0 0 2 2 2 0 Laminin Domain II DUF4407 PF14362.6 OQR92895.1 - 3.4 6.9 10.2 0.71 9.2 5.5 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Metallophos PF00149.28 OQR92896.1 - 1.8e-12 48.2 1.1 2.6e-12 47.7 1.1 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Pur_ac_phosph_N PF16656.5 OQR92896.1 - 4.6e-09 36.7 0.6 4.6e-09 36.7 0.6 2.1 2 0 0 2 2 2 1 Purple acid Phosphatase, N-terminal domain Metallophos_C PF14008.6 OQR92896.1 - 0.00015 22.6 0.1 0.00049 20.9 0.1 2.0 1 0 0 1 1 1 1 Iron/zinc purple acid phosphatase-like protein C LSM14 PF12701.7 OQR92897.1 - 1.8e-28 98.4 0.0 3.8e-28 97.4 0.0 1.6 1 0 0 1 1 1 1 Scd6-like Sm domain FDF PF09532.10 OQR92897.1 - 5.5e-06 27.2 8.0 9.7e-05 23.2 0.0 3.0 2 1 1 3 3 3 2 FDF domain SM-ATX PF14438.6 OQR92897.1 - 0.00034 20.7 0.0 0.00071 19.7 0.0 1.5 1 0 0 1 1 1 1 Ataxin 2 SM domain MFAP1 PF06991.11 OQR92898.1 - 1.9e-64 217.5 35.2 1.9e-64 217.5 35.2 2.4 1 1 2 3 3 3 1 Microfibril-associated/Pre-mRNA processing ubiquitin PF00240.23 OQR92899.1 - 0.043 13.6 0.0 0.16 11.8 0.0 1.9 2 0 0 2 2 2 0 Ubiquitin family ABC2_membrane PF01061.24 OQR92900.1 - 1.6e-71 240.0 63.9 1.3e-40 139.1 24.1 2.9 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.27 OQR92900.1 - 1.4e-31 109.8 0.0 9.3e-16 58.6 0.0 2.4 2 0 0 2 2 2 2 ABC transporter ABC2_membrane_3 PF12698.7 OQR92900.1 - 5.1e-07 29.1 17.6 5.1e-07 29.1 17.6 2.8 2 1 0 2 2 2 1 ABC-2 family transporter protein PDR_assoc PF08370.11 OQR92900.1 - 5.3e-07 29.3 4.8 5.8e-05 22.8 1.3 4.1 4 0 0 4 4 3 2 Plant PDR ABC transporter associated AAA_21 PF13304.6 OQR92900.1 - 7.6e-07 29.2 1.4 0.039 13.8 0.0 3.4 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system PDR_CDR PF06422.12 OQR92900.1 - 7.9e-07 28.9 6.8 2.8e-05 23.9 0.3 3.9 3 0 0 3 3 3 1 CDR ABC transporter AAA_16 PF13191.6 OQR92900.1 - 1.8e-05 25.2 0.0 0.22 11.9 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.6 OQR92900.1 - 2e-05 24.2 3.5 0.014 15.1 0.5 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 OQR92900.1 - 0.00019 21.4 1.2 0.016 15.1 0.2 2.4 2 0 0 2 2 2 1 RsgA GTPase Zeta_toxin PF06414.12 OQR92900.1 - 0.00038 19.8 0.1 0.11 11.8 0.0 2.3 2 0 0 2 2 2 1 Zeta toxin MMR_HSR1 PF01926.23 OQR92900.1 - 0.0004 20.4 1.2 0.12 12.5 0.1 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_22 PF13401.6 OQR92900.1 - 0.0017 18.7 0.0 1.7 9.0 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.6 OQR92900.1 - 0.0082 15.7 0.5 0.2 11.2 0.2 2.3 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 OQR92900.1 - 0.014 15.9 0.0 3.8 8.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.6 OQR92900.1 - 0.038 14.5 0.7 0.78 10.2 0.4 2.3 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 OQR92900.1 - 0.092 13.0 0.2 12 6.1 0.4 2.7 2 1 0 2 2 2 0 AAA domain AAA PF00004.29 OQR92900.1 - 0.18 12.3 0.1 10 6.6 0.1 3.0 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Roc PF08477.13 OQR92900.1 - 0.18 12.0 0.1 28 4.9 0.1 2.5 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Dynamin_N PF00350.23 OQR92900.1 - 0.18 11.8 0.8 4.5 7.3 0.1 2.6 3 0 0 3 3 2 0 Dynamin family AAA_30 PF13604.6 OQR92900.1 - 0.29 10.8 0.7 1.5 8.5 0.3 2.1 2 0 0 2 2 2 0 AAA domain SMC_N PF02463.19 OQR92900.1 - 0.43 10.0 5.7 18 4.6 0.1 3.7 3 1 1 4 4 4 0 RecF/RecN/SMC N terminal domain DUF2568 PF10823.8 OQR92900.1 - 8.3 6.8 16.2 5.1 7.4 1.9 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2568) Mg_trans_NIPA PF05653.14 OQR92948.1 - 1e-11 44.5 1.1 1.2e-11 44.3 1.1 1.0 1 0 0 1 1 1 1 Magnesium transporter NIPA PIP5K PF01504.18 OQR92949.1 - 1.3e-59 201.7 0.0 2.3e-59 200.9 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase 7tm_2 PF00002.24 OQR92949.1 - 0.00011 21.6 7.6 0.00011 21.6 7.6 2.0 2 0 0 2 2 2 1 7 transmembrane receptor (Secretin family) Heliorhodopsin PF18761.1 OQR92949.1 - 0.0085 15.4 0.1 0.0085 15.4 0.1 2.1 3 0 0 3 3 3 1 Heliorhodopsin MFS_1 PF07690.16 OQR92949.1 - 1.7 7.5 12.3 0.23 10.3 6.6 2.1 1 1 1 2 2 2 0 Major Facilitator Superfamily Yip1 PF04893.17 OQR92949.1 - 2.5 7.8 13.0 0.028 14.1 2.3 2.5 2 1 0 2 2 2 0 Yip1 domain DUF1980 PF09323.10 OQR92949.1 - 5.4 6.9 7.4 4.8 7.1 0.1 3.4 3 2 2 5 5 5 0 Domain of unknown function (DUF1980) Pkinase PF00069.25 OQR92952.1 - 9e-10 38.3 0.0 9.5e-10 38.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 OQR92952.1 - 2.3e-09 36.9 0.1 3.4e-09 36.4 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OQR92952.1 - 2.3e-06 27.7 0.0 0.00025 21.0 0.0 2.1 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pkinase_Tyr PF07714.17 OQR92952.1 - 2.3e-05 23.8 0.0 2.6e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.22 OQR92952.1 - 0.0013 18.4 0.3 0.0024 17.5 0.3 1.7 1 1 0 1 1 1 1 RIO1 family Choline_kinase PF01633.20 OQR92952.1 - 0.005 16.4 0.0 0.0074 15.9 0.0 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase EcKinase PF02958.20 OQR92952.1 - 0.051 12.9 0.0 0.063 12.6 0.0 1.3 1 0 0 1 1 1 0 Ecdysteroid kinase WaaY PF06176.11 OQR92952.1 - 0.087 12.4 0.1 0.16 11.5 0.1 1.5 1 1 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) AAA PF00004.29 OQR92953.1 - 3.4e-07 30.8 0.0 6.4e-07 29.9 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 OQR92953.1 - 1.7e-05 25.1 0.0 0.00011 22.5 0.0 2.4 1 1 0 1 1 1 1 AAA domain AAA_7 PF12775.7 OQR92953.1 - 2.1e-05 24.1 0.0 4.2e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_16 PF13191.6 OQR92953.1 - 2.2e-05 24.9 0.0 0.00012 22.5 0.0 2.1 1 1 1 2 2 2 1 AAA ATPase domain AAA_14 PF13173.6 OQR92953.1 - 9.4e-05 22.5 0.0 0.00075 19.5 0.0 2.4 2 1 1 3 3 3 1 AAA domain NTPase_1 PF03266.15 OQR92953.1 - 0.00013 21.9 0.1 0.17 11.8 0.0 2.4 2 0 0 2 2 2 2 NTPase ResIII PF04851.15 OQR92953.1 - 0.00054 20.0 0.0 0.03 14.3 0.0 2.7 2 1 1 3 3 3 1 Type III restriction enzyme, res subunit AAA_5 PF07728.14 OQR92953.1 - 0.0012 18.9 0.0 0.0037 17.3 0.0 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RNA_helicase PF00910.22 OQR92953.1 - 0.0013 19.1 0.0 0.012 16.0 0.0 2.2 2 0 0 2 2 2 1 RNA helicase NACHT PF05729.12 OQR92953.1 - 0.0019 18.1 0.0 0.0042 17.0 0.0 1.7 1 1 0 1 1 1 1 NACHT domain AAA_19 PF13245.6 OQR92953.1 - 0.0022 18.3 0.0 0.0054 17.1 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 OQR92953.1 - 0.0023 17.7 0.0 0.0061 16.3 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 OQR92953.1 - 0.0026 18.3 0.0 0.0059 17.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain ATPase_2 PF01637.18 OQR92953.1 - 0.003 17.5 0.0 0.0064 16.4 0.0 1.5 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea Mg_chelatase PF01078.21 OQR92953.1 - 0.0049 16.3 0.0 0.0088 15.4 0.0 1.3 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI NB-ARC PF00931.22 OQR92953.1 - 0.007 15.6 0.0 0.018 14.3 0.0 1.6 2 0 0 2 2 2 1 NB-ARC domain Rad17 PF03215.15 OQR92953.1 - 0.0085 16.0 0.0 0.02 14.8 0.0 1.6 1 0 0 1 1 1 1 Rad17 P-loop domain Viral_helicase1 PF01443.18 OQR92953.1 - 0.009 15.8 0.0 0.019 14.7 0.0 1.6 1 1 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA_33 PF13671.6 OQR92953.1 - 0.0093 16.1 0.0 0.02 15.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 OQR92953.1 - 0.019 14.8 0.1 0.37 10.5 0.0 2.1 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 OQR92953.1 - 0.022 14.8 0.0 0.045 13.8 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE TniB PF05621.11 OQR92953.1 - 0.029 13.8 0.1 1.6 8.1 0.0 2.3 2 0 0 2 2 2 0 Bacterial TniB protein MCM PF00493.23 OQR92953.1 - 0.03 13.4 0.0 0.063 12.4 0.0 1.5 1 0 0 1 1 1 0 MCM P-loop domain Sigma54_activat PF00158.26 OQR92953.1 - 0.039 13.6 0.0 0.48 10.1 0.0 2.2 2 0 0 2 2 2 0 Sigma-54 interaction domain ABC_tran PF00005.27 OQR92953.1 - 0.043 14.3 0.0 0.1 13.1 0.0 1.7 1 1 0 1 1 1 0 ABC transporter TrwB_AAD_bind PF10412.9 OQR92953.1 - 0.044 12.7 0.0 0.074 12.0 0.0 1.4 1 1 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain AAA_24 PF13479.6 OQR92953.1 - 0.054 13.2 0.0 0.096 12.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain T2SSE PF00437.20 OQR92953.1 - 0.069 12.2 0.0 0.13 11.2 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein Zeta_toxin PF06414.12 OQR92953.1 - 0.074 12.3 0.0 0.13 11.5 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin G-alpha PF00503.20 OQR92953.1 - 0.08 12.1 0.0 0.11 11.7 0.0 1.4 1 0 0 1 1 1 0 G-protein alpha subunit AAA_25 PF13481.6 OQR92953.1 - 0.099 12.2 0.0 1.1 8.8 0.0 2.5 2 1 1 3 3 3 0 AAA domain PduV-EutP PF10662.9 OQR92953.1 - 0.1 12.3 0.0 0.19 11.5 0.0 1.5 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation RuvB_N PF05496.12 OQR92953.1 - 0.13 12.0 0.0 1.7 8.4 0.0 2.3 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain VPS11_C PF12451.8 OQR92954.1 - 2.3e-13 50.1 0.4 6.7e-13 48.6 0.4 1.9 1 0 0 1 1 1 1 Vacuolar protein sorting protein 11 C terminal Clathrin PF00637.20 OQR92954.1 - 1.3e-09 38.1 5.5 0.00017 21.5 0.2 3.2 2 1 0 2 2 2 2 Region in Clathrin and VPS zf-C3H2C3 PF17122.5 OQR92954.1 - 3.9e-07 30.0 9.6 1.2e-06 28.4 9.6 1.9 1 0 0 1 1 1 1 Zinc-finger Vps39_2 PF10367.9 OQR92954.1 - 0.0021 18.5 2.0 0.012 16.1 1.8 2.4 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 2 zf-RING_UBOX PF13445.6 OQR92954.1 - 0.012 15.7 7.9 0.027 14.5 7.9 1.6 1 0 0 1 1 1 0 RING-type zinc-finger zf-C3HC4_2 PF13923.6 OQR92954.1 - 0.013 15.3 9.2 0.03 14.2 9.2 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 OQR92954.1 - 0.065 13.5 4.1 0.19 12.1 4.1 1.8 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-RING_2 PF13639.6 OQR92954.1 - 0.087 13.2 9.1 0.21 12.0 9.1 1.7 1 0 0 1 1 1 0 Ring finger domain Phage_GP20 PF06810.11 OQR92954.1 - 0.096 12.5 2.8 0.22 11.3 0.0 2.4 2 0 0 2 2 2 0 Phage minor structural protein GP20 Prok-RING_1 PF14446.6 OQR92954.1 - 0.39 10.7 6.6 1.1 9.3 6.6 1.7 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 zf-RING_5 PF14634.6 OQR92954.1 - 0.79 9.7 8.7 2.1 8.4 8.7 1.7 1 0 0 1 1 1 0 zinc-RING finger domain Pkinase PF00069.25 OQR92955.1 - 1.4e-05 24.6 0.1 1.5e-05 24.5 0.1 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQR92955.1 - 0.0011 18.3 0.1 0.0012 18.2 0.1 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase WLM PF08325.10 OQR92956.1 - 2.1e-49 168.2 0.1 2.7e-49 167.9 0.1 1.1 1 0 0 1 1 1 1 WLM domain zf-RanBP PF00641.18 OQR92956.1 - 0.0038 16.5 1.8 0.006 15.9 1.8 1.3 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others SVIP PF15811.5 OQR92956.1 - 0.033 14.6 0.1 0.033 14.6 0.1 2.2 3 0 0 3 3 3 0 Small VCP/p97-interacting protein DUF45 PF01863.17 OQR92956.1 - 0.047 13.7 0.2 0.1 12.6 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function DUF45 Pkinase PF00069.25 OQR92957.1 - 8.5e-27 94.2 0.8 6.3e-26 91.3 0.8 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQR92957.1 - 1.4e-09 37.6 0.1 2.3e-09 36.9 0.1 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OQR92957.1 - 8.9e-05 21.4 0.1 0.00011 21.1 0.1 1.1 1 0 0 1 1 1 1 Fungal protein kinase YrbL-PhoP_reg PF10707.9 OQR92957.1 - 0.00083 18.9 0.2 0.002 17.7 0.2 1.6 1 1 0 1 1 1 1 PhoP regulatory network protein YrbL PHA-1 PF06542.11 OQR92957.1 - 0.023 13.5 0.2 0.025 13.4 0.2 1.1 1 0 0 1 1 1 0 Regulator protein PHA-1 DUF2807 PF10988.8 OQR92958.1 - 5.7e-13 49.0 10.0 3.6e-11 43.2 10.0 2.6 1 1 0 1 1 1 1 Putative auto-transporter adhesin, head GIN domain MA3 PF02847.17 OQR92959.1 - 5.9e-26 90.7 0.3 1.6e-25 89.2 0.3 1.8 1 0 0 1 1 1 1 MA3 domain MIF4G PF02854.19 OQR92959.1 - 5.5e-17 62.1 0.0 2.3e-16 60.1 0.0 2.0 2 0 0 2 2 2 1 MIF4G domain DUF5523 PF17661.1 OQR92959.1 - 0.065 12.9 1.3 0.12 12.0 1.3 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5523) CDC50 PF03381.15 OQR92960.1 - 2.1e-85 286.7 0.3 2.7e-85 286.3 0.3 1.1 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family DUF4064 PF13273.6 OQR92960.1 - 0.13 12.5 1.4 8.4 6.7 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4064) TPR_1 PF00515.28 OQR92961.1 - 7.5e-45 149.0 16.4 4.1e-09 35.9 0.1 10.2 10 0 0 10 10 10 6 Tetratricopeptide repeat TPR_2 PF07719.17 OQR92961.1 - 8.3e-45 147.3 19.5 7.7e-07 28.8 0.1 10.6 10 0 0 10 10 10 9 Tetratricopeptide repeat TPR_16 PF13432.6 OQR92961.1 - 4.6e-36 123.2 5.7 6.4e-09 36.3 0.0 7.5 6 1 1 7 7 7 6 Tetratricopeptide repeat TPR_8 PF13181.6 OQR92961.1 - 1.1e-33 112.6 11.1 0.0018 18.3 0.1 10.3 10 0 0 10 10 10 7 Tetratricopeptide repeat ANAPC3 PF12895.7 OQR92961.1 - 3.7e-33 113.6 11.5 1.1e-15 57.6 0.3 5.7 3 2 2 5 5 5 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.6 OQR92961.1 - 1.4e-28 99.2 3.8 2.8e-06 27.7 0.3 8.4 4 2 5 9 9 9 7 Tetratricopeptide repeat TPR_12 PF13424.6 OQR92961.1 - 1.1e-26 92.9 21.6 1.4e-06 28.5 1.0 9.1 5 2 4 9 9 9 8 Tetratricopeptide repeat TPR_14 PF13428.6 OQR92961.1 - 4.9e-24 83.0 10.7 0.052 14.4 0.0 10.4 4 2 6 10 10 10 7 Tetratricopeptide repeat TPR_17 PF13431.6 OQR92961.1 - 1.1e-21 75.6 10.1 0.00097 19.4 0.0 9.6 10 1 1 11 11 9 3 Tetratricopeptide repeat TPR_7 PF13176.6 OQR92961.1 - 3.1e-21 73.8 8.7 0.042 13.9 0.0 10.0 9 1 1 10 10 10 4 Tetratricopeptide repeat TPR_11 PF13414.6 OQR92961.1 - 4.8e-21 74.2 11.2 1.4e-06 27.9 0.1 7.6 4 1 5 9 9 9 5 TPR repeat TPR_6 PF13174.6 OQR92961.1 - 4.1e-16 58.5 14.3 0.0075 16.8 0.0 9.8 11 0 0 11 11 11 3 Tetratricopeptide repeat TPR_9 PF13371.6 OQR92961.1 - 1.6e-10 41.0 6.4 0.00023 21.2 0.0 5.5 5 2 2 7 7 7 2 Tetratricopeptide repeat TPR_10 PF13374.6 OQR92961.1 - 1.4e-07 31.1 21.4 0.56 10.2 0.4 9.2 10 0 0 10 10 10 3 Tetratricopeptide repeat TPR_4 PF07721.14 OQR92961.1 - 8.7e-07 29.0 7.4 0.18 12.5 0.0 5.7 6 0 0 6 6 4 2 Tetratricopeptide repeat HrpB1_HrpK PF09613.10 OQR92961.1 - 3.6e-06 26.6 0.1 0.003 17.2 0.1 3.3 2 1 0 2 2 2 1 Bacterial type III secretion protein (HrpB1_HrpK) TPR_15 PF13429.6 OQR92961.1 - 4.1e-06 26.2 2.1 0.25 10.5 0.0 4.5 2 1 2 4 4 4 1 Tetratricopeptide repeat TPR_21 PF09976.9 OQR92961.1 - 0.00013 21.7 1.3 0.0067 16.2 0.3 3.7 3 1 1 4 4 4 1 Tetratricopeptide repeat-like domain TPR_20 PF14561.6 OQR92961.1 - 0.00024 21.3 3.1 0.005 17.1 0.9 4.0 2 2 2 4 4 4 1 Tetratricopeptide repeat SRP_TPR_like PF17004.5 OQR92961.1 - 0.00056 19.9 2.5 8.8 6.4 0.0 3.7 3 0 0 3 3 3 0 Putative TPR-like repeat ChAPs PF09295.10 OQR92961.1 - 0.0011 18.0 0.0 4.2 6.3 0.0 3.4 2 1 2 4 4 4 2 ChAPs (Chs5p-Arf1p-binding proteins) DUF2225 PF09986.9 OQR92961.1 - 0.0018 18.0 6.8 2.1 8.0 0.2 4.4 4 1 1 5 5 5 2 Uncharacterized protein conserved in bacteria (DUF2225) Type_III_YscG PF09477.10 OQR92961.1 - 0.0035 17.4 0.8 1.9 8.6 0.1 2.5 2 0 0 2 2 2 1 Bacterial type II secretion system chaperone protein (type_III_yscG) BTAD PF03704.17 OQR92961.1 - 0.03 14.8 7.7 0.42 11.0 0.5 4.3 5 1 1 6 6 4 0 Bacterial transcriptional activator domain FAT PF02259.23 OQR92961.1 - 0.11 11.7 7.2 4.7 6.3 3.5 3.9 1 1 0 2 2 2 0 FAT domain PPTA PF01239.22 OQR92961.1 - 0.15 11.8 4.3 0.61 9.9 0.1 3.4 4 0 0 4 4 3 0 Protein prenyltransferase alpha subunit repeat CDC50 PF03381.15 OQR92962.1 - 1.1e-88 297.4 0.6 1.1e-88 297.4 0.6 1.3 1 1 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family PP2C PF00481.21 OQR92963.1 - 2.3e-135 450.2 0.1 4.3e-67 226.5 0.0 2.0 2 0 0 2 2 2 2 Protein phosphatase 2C PP2C_2 PF13672.6 OQR92963.1 - 2.2e-16 60.1 0.0 5.2e-07 29.5 0.0 3.2 2 2 0 2 2 2 2 Protein phosphatase 2C F420H2_quin_red PF04075.14 OQR92963.1 - 0.018 15.1 0.1 19 5.4 0.0 3.0 3 0 0 3 3 3 0 F420H(2)-dependent quinone reductase RMF PF04957.12 OQR92963.1 - 0.079 13.2 0.0 25 5.2 0.0 2.6 2 0 0 2 2 2 0 Ribosome modulation factor DUF3670 PF12419.8 OQR92964.1 - 0.023 14.5 0.0 5.4 6.9 0.0 2.5 2 0 0 2 2 2 0 SNF2 Helicase protein DUF1093 PF06486.11 OQR92964.1 - 0.064 13.9 0.1 40 5.0 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1093) MoCF_biosynth PF00994.24 OQR92965.1 - 1.9e-26 92.5 0.0 7.9e-26 90.5 0.0 2.0 2 0 0 2 2 2 1 Probable molybdopterin binding domain Phage_X PF05155.15 OQR92965.1 - 0.12 12.9 0.2 96 3.5 0.0 3.7 3 0 0 3 3 3 0 Phage X family HMw1_D2 PF18254.1 OQR92965.1 - 0.13 12.7 2.1 65 4.0 0.1 3.6 3 0 0 3 3 3 0 HMW1 domain 2 DUF4235 PF14019.6 OQR92965.1 - 0.15 12.1 2.0 29 4.8 0.1 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF4235) Acyl-CoA_dh_M PF02770.19 OQR93032.1 - 0.013 15.7 0.0 0.014 15.5 0.0 1.1 1 0 0 1 1 1 0 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_ox_N PF14749.6 OQR93033.1 - 1.1e-18 68.0 0.0 1.2e-18 67.9 0.0 1.0 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal TIM PF00121.18 OQR93034.1 - 1.3e-83 280.2 1.1 1.8e-83 279.7 1.1 1.2 1 0 0 1 1 1 1 Triosephosphate isomerase Gp_dh_C PF02800.20 OQR93034.1 - 9e-68 226.8 0.0 1.6e-67 226.0 0.0 1.4 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 OQR93034.1 - 4.1e-37 126.6 0.1 1.1e-36 125.2 0.1 1.8 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DapB_N PF01113.20 OQR93034.1 - 0.016 15.3 0.3 0.093 12.9 0.0 2.4 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus Nucleoside_tran PF01733.18 OQR93035.1 - 3.5e-14 52.9 10.2 3.7e-13 49.5 10.2 2.5 1 1 0 1 1 1 1 Nucleoside transporter EF-hand_7 PF13499.6 OQR93035.1 - 1.1e-11 45.0 0.3 2.9e-11 43.6 0.3 1.8 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 OQR93035.1 - 1.2e-11 43.3 0.6 0.00014 21.1 0.1 2.8 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 OQR93035.1 - 3.8e-10 38.9 0.3 0.00015 21.4 0.0 3.0 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 OQR93035.1 - 2.7e-08 32.9 0.6 0.0051 16.3 0.1 2.7 2 0 0 2 2 2 2 EF hand ALMT PF11744.8 OQR93035.1 - 2.9e-06 26.4 1.2 2.9e-06 26.4 1.2 2.3 2 0 0 2 2 2 1 Aluminium activated malate transporter EF-hand_8 PF13833.6 OQR93035.1 - 0.0031 17.3 0.2 0.45 10.4 0.1 3.6 4 0 0 4 4 4 1 EF-hand domain pair PTEN_C2 PF10409.9 OQR93046.1 - 1e-12 47.9 1.0 1.6e-12 47.3 1.0 1.3 1 0 0 1 1 1 1 C2 domain of PTEN tumour-suppressor protein DSPc PF00782.20 OQR93046.1 - 1.5e-06 28.1 0.0 3e-06 27.1 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 OQR93046.1 - 0.00012 22.1 0.0 0.00019 21.5 0.0 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 OQR93046.1 - 0.011 15.3 0.4 0.024 14.2 0.0 1.8 2 0 0 2 2 2 0 Protein-tyrosine phosphatase DUF411 PF04214.13 OQR93046.1 - 0.028 14.4 0.0 0.06 13.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF IBR PF01485.21 OQR93047.1 - 0.0079 16.4 8.1 0.014 15.6 2.7 2.6 2 0 0 2 2 2 1 IBR domain, a half RING-finger domain zinc_ribbon_9 PF14369.6 OQR93047.1 - 0.059 13.6 3.3 3.1 8.1 0.1 3.3 3 0 0 3 3 3 0 zinc-ribbon zf-RING_7 PF02591.15 OQR93047.1 - 0.95 9.7 5.6 6.9 6.9 0.1 3.5 3 0 0 3 3 3 0 C4-type zinc ribbon domain DUF2946 PF11162.8 OQR93047.1 - 2.2 8.9 4.1 0.94 10.2 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2946) zinc-ribbons_6 PF07191.12 OQR93047.1 - 6 6.9 11.5 1.2 9.1 1.9 3.3 2 1 1 3 3 3 0 zinc-ribbons Pro_dh PF01619.18 OQR93048.1 - 9.6e-81 271.5 1.0 4.4e-80 269.4 1.0 1.8 1 1 0 1 1 1 1 Proline dehydrogenase EF-hand_7 PF13499.6 OQR93048.1 - 4.1e-06 27.1 1.5 0.0039 17.6 0.1 2.1 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 OQR93048.1 - 3.9e-05 23.4 0.0 0.00013 21.7 0.0 1.9 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 OQR93048.1 - 0.012 15.1 0.0 0.034 13.7 0.0 1.8 1 0 0 1 1 1 0 EF hand DENN PF02141.21 OQR93048.1 - 0.04 13.9 0.0 0.095 12.6 0.0 1.6 1 0 0 1 1 1 0 DENN (AEX-3) domain EF-hand_6 PF13405.6 OQR93048.1 - 0.041 13.8 0.0 0.15 12.1 0.0 2.0 1 0 0 1 1 1 0 EF-hand domain UCH PF00443.29 OQR93052.1 - 1.1e-45 156.1 1.2 1.1e-45 156.1 1.2 3.2 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase SAS-6_N PF16531.5 OQR93052.1 - 3.3e-26 91.7 1.7 7.1e-26 90.6 0.0 2.7 2 0 0 2 2 2 1 Centriolar protein SAS N-terminal UCH_1 PF13423.6 OQR93052.1 - 5.1e-18 65.7 0.1 5.1e-18 65.7 0.1 2.7 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase HEAT PF02985.22 OQR93052.1 - 0.091 13.1 0.1 0.58 10.6 0.0 2.5 2 0 0 2 2 2 0 HEAT repeat Hema_stalk PF08720.10 OQR93052.1 - 0.19 11.4 0.2 0.41 10.3 0.2 1.6 1 0 0 1 1 1 0 Influenza C hemagglutinin stalk Sas6_CC PF18594.1 OQR93052.1 - 0.27 11.1 3.0 0.93 9.3 0.2 3.5 3 0 0 3 3 3 0 Sas6/XLF/XRCC4 coiled-coil domain Pkinase PF00069.25 OQR93053.1 - 5.7e-62 209.5 0.1 1e-54 185.7 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OQR93053.1 - 2.9e-60 203.7 0.4 5e-53 180.0 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase EphA2_TM PF14575.6 OQR93053.1 - 2.3e-06 28.4 3.2 0.0029 18.4 0.4 2.7 2 1 0 2 2 2 2 Ephrin type-A receptor 2 transmembrane domain Orf78 PF06024.12 OQR93053.1 - 6.3e-05 23.2 1.1 0.34 11.2 0.8 2.5 2 0 0 2 2 2 2 Orf78 (ac78) Epiglycanin_C PF14654.6 OQR93053.1 - 8.9e-05 22.5 3.4 1 9.5 0.0 3.8 4 0 0 4 4 4 2 Mucin, catalytic, TM and cytoplasmic tail region FAM163 PF15069.6 OQR93053.1 - 0.00027 21.4 0.3 0.042 14.3 0.2 2.7 2 0 0 2 2 2 1 FAM163 family DUF4448 PF14610.6 OQR93053.1 - 0.00033 20.5 1.3 0.069 12.9 0.3 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF4448) ECSCR PF15820.5 OQR93053.1 - 0.0005 19.9 4.5 0.031 14.1 0.6 2.5 2 0 0 2 2 2 1 Endothelial cell-specific chemotaxis regulator CD34_antigen PF06365.12 OQR93053.1 - 0.00061 19.4 2.9 0.57 9.7 0.3 2.7 3 0 0 3 3 3 2 CD34/Podocalyxin family Sigma_reg_N PF13800.6 OQR93053.1 - 0.0013 19.0 2.9 0.31 11.4 0.2 2.9 3 0 0 3 3 2 1 Sigma factor regulator N-terminal TMEM154 PF15102.6 OQR93053.1 - 0.0019 18.1 11.1 0.082 12.8 0.0 3.5 2 1 0 2 2 2 1 TMEM154 protein family Peptidase_M56 PF05569.11 OQR93053.1 - 0.0022 17.3 1.7 0.25 10.5 0.4 2.3 2 0 0 2 2 2 1 BlaR1 peptidase M56 Shisa PF13908.6 OQR93053.1 - 0.0027 18.0 2.0 0.0027 18.0 2.0 3.3 2 1 1 3 3 2 1 Wnt and FGF inhibitory regulator RIFIN PF02009.16 OQR93053.1 - 0.0029 17.5 2.2 0.44 10.4 1.7 2.6 2 0 0 2 2 2 1 Rifin AMA-1 PF02430.15 OQR93053.1 - 0.003 16.6 3.2 1.6 7.6 0.0 2.2 2 0 0 2 2 2 2 Apical membrane antigen 1 Pkinase_fungal PF17667.1 OQR93053.1 - 0.0031 16.3 0.0 0.0052 15.6 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase DAG1 PF05454.11 OQR93053.1 - 0.0034 16.8 7.7 0.2 11.0 0.2 2.5 2 0 0 2 2 2 2 Dystroglycan (Dystrophin-associated glycoprotein 1) RCR PF12273.8 OQR93053.1 - 0.0047 17.6 0.3 0.0047 17.6 0.3 3.4 2 1 1 3 3 2 1 Chitin synthesis regulation, resistance to Congo red SARAF PF06682.12 OQR93053.1 - 0.0058 16.3 0.1 0.27 10.8 0.1 2.3 2 0 0 2 2 2 1 SOCE-associated regulatory factor of calcium homoeostasis Adeno_E3_CR2 PF02439.15 OQR93053.1 - 0.0065 16.2 7.5 0.0065 16.2 7.5 2.5 2 0 0 2 2 2 1 Adenovirus E3 region protein CR2 Cadherin_C_2 PF16492.5 OQR93053.1 - 0.0079 16.9 2.1 0.28 12.0 0.1 2.7 2 0 0 2 2 2 1 Cadherin cytoplasmic C-terminal DUF4366 PF14283.6 OQR93053.1 - 0.0099 15.9 3.5 0.15 12.1 0.0 3.0 3 0 0 3 3 3 1 Domain of unknown function (DUF4366) DUF4064 PF13273.6 OQR93053.1 - 0.013 15.7 0.5 1.3 9.4 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4064) PspB PF06667.12 OQR93053.1 - 0.028 14.5 1.1 8.9 6.4 0.1 2.6 2 0 0 2 2 2 0 Phage shock protein B m04gp34like PF12216.8 OQR93053.1 - 0.03 13.9 4.6 1.3 8.6 0.1 2.4 2 0 0 2 2 2 0 Immune evasion protein DUF2207 PF09972.9 OQR93053.1 - 0.033 12.9 0.2 1.1 8.0 0.1 2.0 1 1 1 2 2 2 0 Predicted membrane protein (DUF2207) Stevor PF17410.2 OQR93053.1 - 0.034 13.7 1.5 0.16 11.5 1.0 2.1 2 0 0 2 2 2 0 Subtelomeric Variable Open Reading frame DUF2561 PF10812.8 OQR93053.1 - 0.039 14.0 0.2 0.039 14.0 0.2 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF2561) Haspin_kinase PF12330.8 OQR93053.1 - 0.043 12.8 2.2 0.51 9.2 0.0 2.8 3 0 0 3 3 3 0 Haspin like kinase domain Amnionless PF14828.6 OQR93053.1 - 0.06 12.2 0.3 2.8 6.7 0.1 2.1 2 0 0 2 2 2 0 Amnionless FtsX PF02687.21 OQR93053.1 - 0.066 13.7 0.7 2.4 8.7 0.2 2.4 2 0 0 2 2 2 0 FtsX-like permease family SP_C-Propep PF08999.10 OQR93053.1 - 0.11 12.3 5.5 1.9 8.3 1.8 2.6 2 0 0 2 2 2 0 Surfactant protein C, N terminal propeptide DUF4834 PF16118.5 OQR93053.1 - 0.11 13.4 0.0 4.9 8.2 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) DUF2371 PF10177.9 OQR93053.1 - 0.12 12.6 0.5 2.2 8.5 0.1 2.4 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2371) Pilin_N PF07790.11 OQR93053.1 - 0.12 13.3 3.2 17 6.4 0.2 2.9 2 0 0 2 2 2 0 Archaeal Type IV pilin, N-terminal Insulin_TMD PF17870.1 OQR93053.1 - 0.13 12.3 13.8 0.081 13.0 1.6 2.5 2 0 0 2 2 2 0 Insulin receptor trans-membrane segment Tmemb_9 PF05434.11 OQR93053.1 - 0.13 12.1 5.2 3.3 7.6 0.0 2.5 2 0 0 2 2 2 0 TMEM9 DUF5385 PF17359.2 OQR93053.1 - 0.14 11.7 2.6 3.7 7.1 0.2 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5385) DUF1218 PF06749.12 OQR93053.1 - 0.15 12.6 1.7 15 6.2 0.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1218) GAPT PF11770.8 OQR93053.1 - 0.16 11.8 2.2 9.1 6.1 0.5 3.3 3 0 0 3 3 3 0 GRB2-binding adapter (GAPT) Baculo_11_kDa PF06143.11 OQR93053.1 - 0.37 10.4 5.6 1.3 8.6 1.4 2.4 2 0 0 2 2 2 0 Baculovirus 11 kDa family 7tm_6 PF02949.20 OQR93053.1 - 0.4 9.7 4.6 0.36 9.9 0.7 2.4 3 0 0 3 3 2 0 7tm Odorant receptor ATP_synt_H PF05493.13 OQR93053.1 - 0.68 10.4 4.0 9.6 6.8 0.2 2.9 2 0 0 2 2 2 0 ATP synthase subunit H Pox_EPC_I2-L1 PF12575.8 OQR93053.1 - 1 9.6 4.9 23 5.3 0.9 2.6 2 0 0 2 2 2 0 Poxvirus entry protein complex L1 and I2 LRRC37AB_C PF14914.6 OQR93053.1 - 1.4 8.8 9.2 0.086 12.8 1.3 2.5 3 0 0 3 3 2 0 LRRC37A/B like protein 1 C-terminal domain DUF3139 PF11337.8 OQR93053.1 - 4.6 8.0 7.0 16 6.2 0.7 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3139) FeoB_associated PF12669.7 OQR93053.1 - 8.3 6.9 16.9 8.1 6.9 4.5 2.5 2 0 0 2 2 2 0 FeoB-associated Cys-rich membrane protein Kinesin PF00225.23 OQR93097.1 - 4.2e-124 413.8 15.8 9.5e-40 136.5 0.1 4.2 4 0 0 4 4 4 4 Kinesin motor domain Microtub_bd PF16796.5 OQR93097.1 - 7.9e-30 103.8 0.0 9.2e-17 61.4 0.0 2.8 2 0 0 2 2 2 2 Microtubule binding AAA_16 PF13191.6 OQR93097.1 - 0.0028 18.1 0.4 4.5 7.6 0.0 3.1 3 0 0 3 3 3 2 AAA ATPase domain IstB_IS21 PF01695.17 OQR93097.1 - 0.003 17.3 0.1 1.2 8.8 0.0 3.1 3 0 0 3 3 3 2 IstB-like ATP binding protein AAA_22 PF13401.6 OQR93097.1 - 0.72 10.1 7.1 11 6.3 0.0 3.6 3 0 0 3 3 3 0 AAA domain Adaptin_binding PF10199.9 OQR93097.1 - 3.7 8.2 6.4 0.52 10.9 1.8 2.1 2 1 0 2 2 2 0 Alpha and gamma adaptin binding protein p34 Baculo_p24 PF05073.12 OQR93097.1 - 5.2 6.8 12.5 5.5 6.7 0.1 3.9 4 1 0 4 4 4 0 Baculovirus P24 capsid protein DUF4260 PF14079.6 OQR93098.1 - 3e-28 98.0 1.6 3.5e-28 97.8 1.6 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4260) Annexin PF00191.20 OQR93099.1 - 1.4e-55 185.2 0.1 3.4e-13 49.4 0.0 4.2 4 0 0 4 4 4 4 Annexin Kinesin PF00225.23 OQR93100.1 - 5.1e-63 213.0 1.4 8.2e-38 130.2 0.2 2.1 2 0 0 2 2 2 2 Kinesin motor domain Microtub_bd PF16796.5 OQR93100.1 - 1.8e-16 60.4 0.0 3.2e-16 59.6 0.0 1.4 1 0 0 1 1 1 1 Microtubule binding zf-CCCH PF00642.24 OQR93101.1 - 4.5e-09 36.0 2.6 4.5e-09 36.0 2.6 2.4 4 0 0 4 4 4 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-C3HC4_3 PF13920.6 OQR93101.1 - 3.4e-06 26.8 5.8 6.4e-06 25.9 5.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OQR93101.1 - 4.4e-06 26.6 7.5 1.1e-05 25.4 7.5 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_2 PF13639.6 OQR93101.1 - 6.7e-06 26.3 8.6 6.7e-06 26.3 8.6 1.8 2 0 0 2 2 2 1 Ring finger domain zf_CCCH_4 PF18345.1 OQR93101.1 - 3.5e-05 23.7 5.0 9.2e-05 22.4 5.0 1.8 1 0 0 1 1 1 1 Zinc finger domain zf-C3HC4 PF00097.25 OQR93101.1 - 0.00017 21.4 9.4 0.00039 20.2 9.4 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 OQR93101.1 - 0.00024 20.9 8.8 0.00049 19.9 8.8 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OQR93101.1 - 0.00052 19.9 10.8 0.0011 18.9 10.8 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-CCCH_4 PF18044.1 OQR93101.1 - 0.0041 16.9 3.3 0.0041 16.9 3.3 2.4 3 0 0 3 3 3 1 CCCH-type zinc finger Prok-RING_4 PF14447.6 OQR93101.1 - 0.027 14.3 5.1 0.062 13.2 5.1 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 OQR93101.1 - 0.079 13.1 7.7 0.25 11.5 7.7 1.9 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_10 PF16685.5 OQR93101.1 - 0.14 12.4 7.6 0.061 13.5 4.9 1.8 2 0 0 2 2 1 0 zinc RING finger of MSL2 FYVE PF01363.21 OQR93101.1 - 0.42 10.8 8.8 1.3 9.2 8.6 1.9 1 1 0 1 1 1 0 FYVE zinc finger Peptidase_S9 PF00326.21 OQR93102.1 - 1.8e-36 125.7 0.1 3e-36 124.9 0.1 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family DPPIV_N PF00930.21 OQR93102.1 - 1.8e-30 105.9 0.7 1.6e-29 102.8 0.1 2.5 3 0 0 3 3 3 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region VHL PF01847.16 OQR93102.1 - 7.2e-14 51.5 0.4 1.6e-05 24.7 0.1 2.7 2 0 0 2 2 2 2 VHL beta domain Esterase PF00756.20 OQR93102.1 - 7e-05 22.6 0.0 0.00015 21.5 0.0 1.5 1 0 0 1 1 1 1 Putative esterase Peptidase_S15 PF02129.18 OQR93102.1 - 0.0035 17.0 0.0 0.0064 16.1 0.0 1.5 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Methyltransf_16 PF10294.9 OQR93103.1 - 3.6e-32 111.5 0.0 6.1e-32 110.7 0.0 1.3 1 0 0 1 1 1 1 Lysine methyltransferase Pkinase_Tyr PF07714.17 OQR93103.1 - 3.6e-17 62.5 0.0 5.7e-17 61.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OQR93103.1 - 1.8e-13 50.5 0.0 3.4e-13 49.6 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain LRR_4 PF12799.7 OQR93103.1 - 0.0031 17.9 8.5 1.9 9.0 0.0 4.0 3 0 0 3 3 3 2 Leucine Rich repeats (2 copies) Methyltransf_23 PF13489.6 OQR93103.1 - 0.063 13.1 0.0 0.16 11.8 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Ank PF00023.30 OQR93104.1 - 3.4e-18 65.2 8.6 1.6e-06 28.3 0.4 4.9 4 1 1 5 5 5 3 Ankyrin repeat Ank_2 PF12796.7 OQR93104.1 - 4.9e-18 65.5 1.9 6.2e-11 42.7 0.3 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OQR93104.1 - 1.6e-11 44.2 4.1 2.9e-05 24.2 0.7 3.3 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 OQR93104.1 - 6.9e-09 36.1 1.2 0.0001 22.8 0.1 3.1 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQR93104.1 - 1.3e-08 34.4 0.5 0.14 12.8 0.0 3.6 2 1 1 3 3 3 3 Ankyrin repeat Isochorismatase PF00857.20 OQR93105.1 - 5.1e-27 95.2 0.3 7.4e-27 94.6 0.3 1.2 1 0 0 1 1 1 1 Isochorismatase family AAA PF00004.29 OQR93106.1 - 1.2e-52 177.8 0.0 9.8e-40 136.0 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 OQR93106.1 - 2e-09 37.1 0.1 6.6e-09 35.4 0.1 1.9 1 1 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 OQR93106.1 - 1.3e-08 35.4 0.1 0.0078 16.6 0.0 2.9 2 1 0 2 2 2 2 AAA ATPase domain IstB_IS21 PF01695.17 OQR93106.1 - 4.1e-08 33.2 0.0 0.00047 19.9 0.0 2.5 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_22 PF13401.6 OQR93106.1 - 5.7e-08 33.1 2.7 0.086 13.1 0.3 4.2 2 2 1 3 3 3 2 AAA domain AAA_2 PF07724.14 OQR93106.1 - 6.2e-07 29.7 0.1 4e-05 23.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 OQR93106.1 - 6.6e-07 29.4 0.1 0.0036 17.3 0.1 3.0 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 OQR93106.1 - 1.2e-06 28.3 0.0 0.094 12.5 0.0 3.0 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 OQR93106.1 - 6.9e-06 26.3 0.0 0.16 12.1 0.0 2.4 2 0 0 2 2 2 2 AAA domain NB-ARC PF00931.22 OQR93106.1 - 8.5e-06 25.1 0.0 0.032 13.4 0.0 2.2 2 0 0 2 2 2 2 NB-ARC domain Mg_chelatase PF01078.21 OQR93106.1 - 8.7e-06 25.3 0.5 0.004 16.6 0.1 2.3 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI TIP49 PF06068.13 OQR93106.1 - 2.1e-05 23.9 0.0 0.081 12.1 0.0 2.4 2 0 0 2 2 2 2 TIP49 P-loop domain CDC48_2 PF02933.17 OQR93106.1 - 3.4e-05 23.5 0.2 0.00089 19.0 0.0 2.9 3 0 0 3 3 3 1 Cell division protein 48 (CDC48), domain 2 ATPase_2 PF01637.18 OQR93106.1 - 5.4e-05 23.2 0.1 3.1 7.6 0.0 3.8 2 2 1 4 4 4 2 ATPase domain predominantly from Archaea Sigma54_activat PF00158.26 OQR93106.1 - 0.00014 21.7 0.1 0.12 12.0 0.0 2.4 2 0 0 2 2 2 2 Sigma-54 interaction domain TniB PF05621.11 OQR93106.1 - 0.00019 20.9 0.3 5.8 6.3 0.0 4.1 3 1 1 4 4 4 0 Bacterial TniB protein TsaE PF02367.17 OQR93106.1 - 0.00021 21.3 0.0 0.8 9.7 0.0 2.4 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_24 PF13479.6 OQR93106.1 - 0.00026 20.8 0.4 0.38 10.4 0.0 3.3 3 1 0 3 3 3 1 AAA domain ABC_tran PF00005.27 OQR93106.1 - 0.00031 21.3 0.0 0.15 12.5 0.0 2.8 2 1 0 2 2 2 1 ABC transporter ATPase PF06745.13 OQR93106.1 - 0.00031 20.2 0.0 0.024 14.0 0.0 2.5 2 0 0 2 2 2 1 KaiC RNA_helicase PF00910.22 OQR93106.1 - 0.00032 21.0 0.0 0.16 12.4 0.0 2.6 2 0 0 2 2 2 1 RNA helicase NACHT PF05729.12 OQR93106.1 - 0.00032 20.6 0.2 1.1 9.2 0.0 3.0 2 1 0 2 2 2 2 NACHT domain AAA_14 PF13173.6 OQR93106.1 - 0.00079 19.5 0.0 0.11 12.5 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 OQR93106.1 - 0.0012 18.4 0.1 0.16 11.4 0.0 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_18 PF13238.6 OQR93106.1 - 0.0019 18.8 0.0 1.5 9.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain PhoH PF02562.16 OQR93106.1 - 0.0024 17.4 0.3 0.94 8.9 0.1 2.3 2 0 0 2 2 2 1 PhoH-like protein Zeta_toxin PF06414.12 OQR93106.1 - 0.0029 16.9 0.1 0.53 9.5 0.1 2.5 2 0 0 2 2 2 1 Zeta toxin AAA_30 PF13604.6 OQR93106.1 - 0.005 16.6 0.1 3.6 7.3 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.6 OQR93106.1 - 0.0083 16.4 0.0 1.6 9.0 0.0 2.6 2 0 0 2 2 2 1 AAA domain Rad17 PF03215.15 OQR93106.1 - 0.0085 16.0 0.0 0.11 12.4 0.0 2.3 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_3 PF07726.11 OQR93106.1 - 0.011 15.6 0.0 2.8 7.8 0.0 2.6 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Bac_DnaA PF00308.18 OQR93106.1 - 0.016 15.0 0.0 0.74 9.6 0.0 2.3 2 0 0 2 2 2 0 Bacterial dnaA protein AAA_19 PF13245.6 OQR93106.1 - 0.018 15.4 0.5 1.3 9.3 0.0 3.2 2 1 1 3 3 3 0 AAA domain AAA_25 PF13481.6 OQR93106.1 - 0.029 13.9 5.6 5.2 6.6 0.7 3.8 2 2 2 4 4 4 0 AAA domain AAA_11 PF13086.6 OQR93106.1 - 0.1 12.4 0.0 9.6 5.9 0.0 2.2 2 0 0 2 2 2 0 AAA domain DUF2075 PF09848.9 OQR93106.1 - 0.11 11.7 0.1 5.1 6.2 0.0 2.5 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) DUF1336 PF07059.12 OQR93121.1 - 3.7e-64 216.9 0.0 1.1e-63 215.4 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF1336) START PF01852.19 OQR93121.1 - 4.2e-21 75.3 0.4 8.9e-21 74.3 0.4 1.5 1 0 0 1 1 1 1 START domain PH PF00169.29 OQR93121.1 - 4.5e-09 36.8 0.1 1e-08 35.7 0.1 1.6 1 0 0 1 1 1 1 PH domain Polyketide_cyc2 PF10604.9 OQR93121.1 - 0.0024 18.1 0.1 0.0067 16.7 0.1 1.7 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport PH_8 PF15409.6 OQR93121.1 - 0.0033 17.7 0.3 0.1 12.9 0.0 2.5 2 0 0 2 2 2 1 Pleckstrin homology domain TCR PF03638.15 OQR93122.1 - 1.1e-25 89.6 52.2 2.7e-13 50.0 20.1 2.3 2 0 0 2 2 2 2 Tesmin/TSO1-like CXC domain, cysteine-rich domain F-box-like PF12937.7 OQR93122.1 - 3.1e-05 23.8 0.1 6e-05 22.8 0.1 1.4 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 OQR93122.1 - 0.0013 18.5 0.0 0.0028 17.5 0.0 1.5 1 0 0 1 1 1 1 F-box domain MSL2-CXC PF16682.5 OQR93122.1 - 7.6 6.8 43.6 8.5 6.6 16.0 2.7 2 1 0 2 2 2 0 CXC domain of E3 ubiquitin-protein ligase MSL2 MFS_1 PF07690.16 OQR93123.1 - 4.4e-41 141.0 70.0 4e-25 88.5 28.2 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily DUF3925 PF13063.6 OQR93123.1 - 0.088 13.0 9.3 0.87 9.8 0.8 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3925) Kinocilin PF15033.6 OQR93123.1 - 2.6 7.7 7.5 12 5.6 0.2 3.6 2 1 0 3 3 3 0 Kinocilin protein YL1 PF05764.13 OQR93124.1 - 0.077 13.1 2.4 0.1 12.7 2.4 1.1 1 0 0 1 1 1 0 YL1 nuclear protein Crystall PF00030.19 OQR93126.1 - 6.1e-06 26.4 0.3 2e-05 24.7 0.3 2.0 1 0 0 1 1 1 1 Beta/Gamma crystallin Crystall_3 PF08964.10 OQR93126.1 - 0.033 14.3 0.4 4.3 7.6 0.0 2.4 1 1 1 2 2 2 0 Beta/Gamma crystallin FA_hydroxylase PF04116.13 OQR93127.1 - 4.4e-07 30.3 15.1 4.4e-07 30.3 15.1 2.0 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily DUF5082 PF16888.5 OQR93128.1 - 0.0088 16.3 18.2 0.26 11.6 2.1 2.6 1 1 1 2 2 2 2 Domain of unknown function (DUF5082) adh_short PF00106.25 OQR93129.1 - 2.2e-50 170.8 0.2 3e-50 170.4 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OQR93129.1 - 5.1e-31 108.0 0.1 6.6e-31 107.7 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OQR93129.1 - 1.5e-13 51.0 0.1 2.1e-13 50.6 0.1 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 OQR93129.1 - 9.2e-06 25.3 0.2 2.2e-05 24.1 0.2 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.18 OQR93129.1 - 0.051 13.5 0.0 0.085 12.7 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_10 PF13460.6 OQR93129.1 - 0.056 13.3 0.0 0.09 12.7 0.0 1.4 1 0 0 1 1 1 0 NAD(P)H-binding LANC_like PF05147.13 OQR93130.1 - 0.11 11.1 0.0 0.12 10.9 0.0 1.0 1 0 0 1 1 1 0 Lanthionine synthetase C-like protein DENN PF02141.21 OQR93134.1 - 5.8e-34 117.7 14.9 9.3e-34 117.0 3.5 4.4 4 1 0 4 4 4 1 DENN (AEX-3) domain RGS PF00615.19 OQR93134.1 - 1.9e-10 41.0 7.6 4.5e-05 23.7 0.1 3.0 3 0 0 3 3 3 2 Regulator of G protein signaling domain dDENN PF03455.19 OQR93134.1 - 0.00085 19.3 0.2 0.00085 19.3 0.2 2.3 2 0 0 2 2 2 1 dDENN domain Polysacc_synt_C PF14667.6 OQR93135.1 - 0.045 13.8 1.0 0.055 13.5 1.0 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis C-terminal domain Pkinase PF00069.25 OQR93136.1 - 1.5e-70 237.6 0.0 2.2e-70 237.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQR93136.1 - 2.5e-42 144.9 0.0 3.7e-42 144.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 OQR93136.1 - 2.2e-07 30.5 0.4 3.7e-07 29.7 0.4 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.9 OQR93136.1 - 2.6e-06 27.1 0.4 5.1e-06 26.2 0.4 1.4 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL Kinase-like PF14531.6 OQR93136.1 - 4.5e-06 26.2 0.0 6.5e-06 25.7 0.0 1.4 1 1 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 OQR93136.1 - 4.9e-05 22.3 0.1 7.2e-05 21.7 0.1 1.3 1 0 0 1 1 1 1 Fungal protein kinase RIO1 PF01163.22 OQR93136.1 - 0.00012 21.7 1.8 0.00021 21.0 1.8 1.3 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 OQR93136.1 - 0.00064 19.7 0.0 0.0017 18.3 0.0 1.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family BRCA-2_OB3 PF09104.10 OQR93136.1 - 0.048 13.3 0.1 0.13 11.9 0.1 1.7 1 0 0 1 1 1 0 BRCA2, oligonucleotide/oligosaccharide-binding, domain 3 FTA2 PF13095.6 OQR93136.1 - 0.058 13.0 0.2 0.17 11.5 0.2 1.8 1 1 1 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 DUF848 PF05852.11 OQR93136.1 - 0.088 12.9 0.1 0.43 10.7 0.0 2.1 2 0 0 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) DUF4602 PF15375.6 OQR93152.1 - 7.4e-18 65.2 11.8 9.1e-18 64.9 11.8 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4602) ASH PF15780.5 OQR93153.1 - 1.5e-17 63.6 9.8 0.00067 19.8 0.0 8.4 9 0 0 9 9 9 4 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin DUF5001 PF16392.5 OQR93153.1 - 0.00011 22.1 0.2 10 6.1 0.0 5.4 5 0 0 5 5 5 1 Ig-like domain DUF1573 PF07610.11 OQR93153.1 - 0.00019 21.4 0.9 2.9 8.0 0.0 5.1 6 0 0 6 6 6 2 Protein of unknown function (DUF1573) TMEM131_like PF12371.8 OQR93153.1 - 0.00029 21.0 2.9 0.57 10.5 0.0 4.3 4 0 0 4 4 4 2 Transmembrane protein 131-like Motile_Sperm PF00635.26 OQR93153.1 - 0.0008 19.2 2.3 0.21 11.4 0.0 4.6 5 1 0 5 5 5 1 MSP (Major sperm protein) domain MYCBPAP PF14646.6 OQR93153.1 - 0.0022 17.0 0.0 0.0096 14.9 0.0 2.2 2 1 0 2 2 2 1 MYCBP-associated protein family Gryzun-like PF12742.7 OQR93153.1 - 0.007 16.4 0.0 46 4.1 0.0 4.5 4 0 0 4 4 4 0 Gryzun, putative Golgi trafficking PTR2 PF00854.21 OQR93154.1 - 5.5e-60 203.3 12.6 8.7e-60 202.6 12.6 1.3 1 0 0 1 1 1 1 POT family PSI_PsaJ PF01701.18 OQR93154.1 - 0.047 14.2 0.6 0.047 14.2 0.6 2.5 2 0 0 2 2 2 0 Photosystem I reaction centre subunit IX / PsaJ DUF2627 PF11118.8 OQR93154.1 - 0.68 10.5 3.5 12 6.5 0.2 3.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2627) Chordopox_A13L PF05961.11 OQR93154.1 - 0.89 9.8 2.7 4.8 7.5 0.0 3.0 3 0 0 3 3 3 0 Chordopoxvirus A13L protein Pkinase PF00069.25 OQR93157.1 - 4.4e-48 163.9 0.0 9.9e-48 162.8 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQR93157.1 - 1.6e-44 152.2 0.0 2.5e-44 151.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase SAM_1 PF00536.30 OQR93157.1 - 5.7e-08 33.1 0.0 2.5e-06 27.8 0.0 2.6 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) Pkinase_fungal PF17667.1 OQR93157.1 - 4.1e-07 29.1 0.1 6.5e-07 28.5 0.1 1.2 1 0 0 1 1 1 1 Fungal protein kinase PH PF00169.29 OQR93157.1 - 7.8e-07 29.6 0.9 2.2e-06 28.1 0.1 2.2 2 0 0 2 2 2 1 PH domain SAM_2 PF07647.17 OQR93157.1 - 1.7e-06 28.0 0.1 2.9e-05 24.1 0.0 2.6 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) Haspin_kinase PF12330.8 OQR93157.1 - 3.9e-05 22.8 0.1 6.3e-05 22.1 0.1 1.3 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 OQR93157.1 - 0.00083 19.3 0.5 0.0038 17.2 0.2 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family BCL_N PF04714.13 OQR93157.1 - 0.011 15.7 2.3 0.076 13.1 0.9 2.4 2 0 0 2 2 2 0 BCL7, N-terminal conserver region Kinase-like PF14531.6 OQR93157.1 - 0.021 14.2 0.0 0.038 13.3 0.0 1.4 1 0 0 1 1 1 0 Kinase-like PH_15 PF17339.2 OQR93157.1 - 0.11 12.4 0.0 0.23 11.3 0.0 1.5 1 0 0 1 1 1 0 PH domain PH_9 PF15410.6 OQR93157.1 - 0.12 12.8 0.8 0.34 11.3 0.8 1.7 1 1 0 1 1 1 0 Pleckstrin homology domain LRR_8 PF13855.6 OQR93158.1 - 1.7e-14 53.3 27.8 5.3e-07 29.3 4.8 4.4 2 2 3 5 5 5 5 Leucine rich repeat LRR_4 PF12799.7 OQR93158.1 - 5.3e-11 42.6 37.1 0.00019 21.7 4.0 5.9 3 2 4 7 7 7 5 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 OQR93158.1 - 0.68 10.7 29.2 6.3 7.8 2.3 7.5 7 1 0 7 7 7 0 Leucine Rich Repeat BUD22 PF09073.10 OQR93158.1 - 2 7.7 36.0 0.025 13.9 28.6 1.5 2 0 0 2 2 2 0 BUD22 RP-C_C PF11800.8 OQR93158.1 - 2.2 8.3 12.6 0.063 13.4 5.6 2.0 2 0 0 2 2 2 0 Replication protein C C-terminal region Herpes_LMP1 PF05297.11 OQR93158.1 - 7.2 5.7 7.5 11 5.1 7.5 1.1 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) Ank_2 PF12796.7 OQR93160.1 - 1.6e-20 73.5 5.1 0.0002 21.9 0.1 4.3 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQR93160.1 - 2.6e-17 63.0 9.2 0.0032 18.0 0.1 6.7 3 3 5 8 8 8 7 Ankyrin repeats (many copies) Ank_5 PF13857.6 OQR93160.1 - 2e-12 47.1 4.3 0.039 14.3 0.0 6.5 2 2 6 8 8 8 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQR93160.1 - 3.3e-11 42.4 0.7 3.1 8.7 0.0 8.0 9 0 0 9 9 9 2 Ankyrin repeat DUF5049 PF16468.5 OQR93160.1 - 4.1e-05 23.4 0.2 25 4.8 0.0 5.9 5 1 1 6 6 6 1 Domain of unknown function (DUF5049) Ank PF00023.30 OQR93160.1 - 0.0009 19.6 0.4 35 5.1 0.1 5.6 2 2 0 2 2 2 0 Ankyrin repeat Myb_DNA-binding PF00249.31 OQR93161.1 - 1.5e-07 31.5 0.0 0.0095 16.1 0.0 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OQR93161.1 - 6.5e-06 26.3 0.0 0.0078 16.4 0.0 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 OQR93161.1 - 0.014 15.5 0.4 9 6.5 0.1 3.2 2 1 1 3 3 3 0 Myb/SANT-like DNA-binding domain PTPS_related PF10131.9 OQR93161.1 - 0.15 10.3 0.1 0.29 9.4 0.0 1.4 2 0 0 2 2 2 0 6-pyruvoyl-tetrahydropterin synthase related domain; membrane protein Pkinase PF00069.25 OQR93162.1 - 9.9e-70 234.9 0.0 1.7e-69 234.2 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQR93162.1 - 1.4e-36 126.1 0.0 2.4e-36 125.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase AAA PF00004.29 OQR93162.1 - 9.3e-18 64.9 0.0 2.6e-17 63.5 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Pkinase_fungal PF17667.1 OQR93162.1 - 2.8e-05 23.1 0.0 8.6e-05 21.5 0.0 1.8 1 0 0 1 1 1 1 Fungal protein kinase AAA_14 PF13173.6 OQR93162.1 - 0.00079 19.5 0.0 0.0039 17.2 0.0 2.2 1 0 0 1 1 1 1 AAA domain Kinase-like PF14531.6 OQR93162.1 - 0.003 16.9 0.0 0.0087 15.4 0.0 1.8 2 0 0 2 2 2 1 Kinase-like AAA_22 PF13401.6 OQR93162.1 - 0.0032 17.7 0.0 0.079 13.2 0.0 3.0 2 1 0 2 2 1 1 AAA domain AAA_2 PF07724.14 OQR93162.1 - 0.0079 16.3 0.0 0.029 14.5 0.0 2.0 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 OQR93162.1 - 0.008 15.9 0.0 0.028 14.1 0.0 1.9 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain APH PF01636.23 OQR93162.1 - 0.01 15.8 0.0 0.022 14.7 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family AAA_16 PF13191.6 OQR93162.1 - 0.021 15.2 0.1 0.13 12.7 0.0 2.4 2 0 0 2 2 2 0 AAA ATPase domain TIP49 PF06068.13 OQR93162.1 - 0.026 13.7 0.0 0.053 12.7 0.0 1.4 1 0 0 1 1 1 0 TIP49 P-loop domain IstB_IS21 PF01695.17 OQR93162.1 - 0.028 14.2 0.0 0.31 10.7 0.0 2.4 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_5 PF07728.14 OQR93162.1 - 0.046 13.7 0.0 0.13 12.2 0.0 1.8 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 OQR93162.1 - 0.062 13.5 0.0 0.24 11.6 0.0 2.0 1 0 0 1 1 1 0 AAA domain Kdo PF06293.14 OQR93162.1 - 0.074 12.4 0.0 0.19 11.1 0.0 1.6 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Mg_chelatase PF01078.21 OQR93162.1 - 0.087 12.2 0.1 0.2 11.0 0.1 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Collagen PF01391.18 OQR93162.1 - 0.65 9.8 26.6 0.53 10.1 8.8 3.4 3 0 0 3 3 3 0 Collagen triple helix repeat (20 copies) PurL_C PF16904.5 OQR93163.1 - 0.01 16.1 0.1 0.012 15.9 0.1 1.1 1 0 0 1 1 1 0 Phosphoribosylformylglycinamidine synthase II C-terminus Na_H_Exchanger PF00999.21 OQR93164.1 - 8.5e-60 202.5 39.7 1e-59 202.2 39.7 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family FeoB_C PF07664.12 OQR93164.1 - 0.14 11.8 4.9 2 8.1 0.2 4.0 3 0 0 3 3 3 0 Ferrous iron transport protein B C terminus TraL PF07178.11 OQR93164.1 - 5.2 7.6 15.2 0.84 10.1 1.8 3.9 4 0 0 4 4 4 0 TraL protein ABC2_membrane PF01061.24 OQR93166.1 - 3.3e-65 219.4 64.2 2.6e-36 125.0 27.6 2.6 2 0 0 2 2 2 2 ABC-2 type transporter ABC_tran PF00005.27 OQR93166.1 - 7.6e-35 120.4 0.0 2.3e-16 60.5 0.0 2.5 2 0 0 2 2 2 2 ABC transporter RsgA_GTPase PF03193.16 OQR93166.1 - 1.9e-07 31.2 0.1 0.00022 21.2 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase PDR_assoc PF08370.11 OQR93166.1 - 1.9e-06 27.5 0.5 8.2e-06 25.5 0.5 2.1 1 0 0 1 1 1 1 Plant PDR ABC transporter associated AAA_25 PF13481.6 OQR93166.1 - 2.6e-06 27.2 0.3 0.052 13.1 0.1 2.5 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.6 OQR93166.1 - 1.5e-05 24.6 2.2 0.012 15.4 0.2 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_21 PF13304.6 OQR93166.1 - 5e-05 23.3 0.1 4.3 7.0 0.0 3.4 3 0 0 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system ABC2_membrane_3 PF12698.7 OQR93166.1 - 5e-05 22.6 20.7 5e-05 22.6 20.7 2.8 2 1 0 2 2 1 1 ABC-2 family transporter protein AAA_22 PF13401.6 OQR93166.1 - 5.2e-05 23.6 0.2 0.12 12.7 0.1 3.1 3 0 0 3 3 3 1 AAA domain AAA_33 PF13671.6 OQR93166.1 - 0.00048 20.3 0.1 0.8 9.9 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 OQR93166.1 - 0.00068 20.1 0.1 1.4 9.3 0.0 2.8 2 0 0 2 2 2 2 AAA ATPase domain Globin PF00042.22 OQR93166.1 - 0.0013 19.3 2.2 2.3 8.8 0.2 3.2 2 2 0 2 2 2 2 Globin AAA_30 PF13604.6 OQR93166.1 - 0.0039 16.9 4.0 1.2 8.9 0.5 2.5 2 1 0 2 2 2 2 AAA domain AAA_23 PF13476.6 OQR93166.1 - 0.0081 16.7 0.6 1.1 9.8 0.1 2.6 2 0 0 2 2 2 1 AAA domain TsaE PF02367.17 OQR93166.1 - 0.0098 15.9 1.7 1.2 9.2 0.3 2.7 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE Peptidase_C28 PF05408.11 OQR93166.1 - 0.018 14.8 0.0 0.06 13.1 0.0 1.7 2 0 0 2 2 2 0 Foot-and-mouth virus L-proteinase AAA_24 PF13479.6 OQR93166.1 - 0.02 14.6 1.5 3.7 7.2 0.5 2.3 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 OQR93166.1 - 0.026 15.1 0.1 9.9 6.7 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 OQR93166.1 - 0.029 14.8 1.3 2.9 8.3 0.0 3.6 3 1 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) SMC_N PF02463.19 OQR93166.1 - 0.03 13.8 0.0 13 5.2 0.0 3.0 3 1 0 3 3 3 0 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 OQR93166.1 - 0.039 14.0 0.3 9 6.4 0.1 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase MeaB PF03308.16 OQR93166.1 - 0.086 11.8 0.6 8.3 5.3 0.1 2.5 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB RNA_helicase PF00910.22 OQR93166.1 - 0.11 12.8 0.2 29 5.1 0.0 2.7 2 0 0 2 2 2 0 RNA helicase AAA_28 PF13521.6 OQR93166.1 - 0.17 12.1 0.5 23 5.2 0.1 2.5 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 OQR93166.1 - 0.29 10.4 2.5 4.8 6.4 0.2 2.3 2 0 0 2 2 2 0 Zeta toxin cobW PF02492.19 OQR93166.1 - 0.34 10.5 1.8 15 5.1 0.2 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_19 PF13245.6 OQR93166.1 - 1 9.7 3.4 5.4 7.3 0.0 2.7 3 0 0 3 3 2 0 AAA domain NACHT PF05729.12 OQR93166.1 - 2.6 7.9 4.8 19 5.2 0.3 2.4 2 0 0 2 2 2 0 NACHT domain DUF87 PF01935.17 OQR93166.1 - 6.5 6.8 5.6 24 4.9 0.4 2.5 2 0 0 2 2 2 0 Helicase HerA, central domain PDR_CDR PF06422.12 OQR93166.1 - 9.4 6.2 8.3 2 8.4 0.0 3.4 3 0 0 3 3 2 0 CDR ABC transporter RRM_1 PF00076.22 OQR93167.1 - 2.1e-14 53.1 0.1 3.2e-14 52.5 0.1 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 OQR93167.1 - 0.00018 21.1 0.0 0.00025 20.6 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 OQR93167.1 - 0.006 16.4 0.0 0.0097 15.8 0.0 1.3 1 0 0 1 1 1 1 Occluded RNA-recognition motif TRA-1_regulated PF02343.16 OQR93167.1 - 0.1 12.6 0.0 0.16 12.1 0.0 1.2 1 0 0 1 1 1 0 TRA-1 regulated protein R03H10.4 DUF4508 PF14969.6 OQR93168.1 - 0.0057 16.9 0.3 0.42 10.9 0.0 3.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4508) LcrV PF04792.12 OQR93168.1 - 0.041 13.2 0.3 0.71 9.1 0.3 2.3 1 1 0 2 2 2 0 V antigen (LcrV) protein TPR_14 PF13428.6 OQR93168.1 - 0.31 12.0 2.2 16 6.6 0.1 4.3 4 1 1 5 5 5 0 Tetratricopeptide repeat DUF3361 PF11841.8 OQR93168.1 - 1.5 8.8 4.3 4.8 7.1 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3361) DUF1754 PF08555.10 OQR93173.1 - 6.5e-07 30.1 1.4 6.5e-07 30.1 1.4 2.3 2 1 0 2 2 2 1 Eukaryotic family of unknown function (DUF1754) EF-hand_7 PF13499.6 OQR93174.1 - 5.3e-11 42.8 2.2 1.4e-08 35.0 0.4 3.5 3 0 0 3 3 3 1 EF-hand domain pair SAM_1 PF00536.30 OQR93174.1 - 1.3e-10 41.5 0.0 3.8e-10 40.0 0.0 1.9 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) EF-hand_6 PF13405.6 OQR93174.1 - 9.1e-08 31.4 1.7 0.0096 15.8 0.1 4.0 3 0 0 3 3 3 2 EF-hand domain SAM_2 PF07647.17 OQR93174.1 - 1.2e-07 31.7 0.0 3.9e-07 30.1 0.0 1.8 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) GAF_2 PF13185.6 OQR93174.1 - 2.1e-07 31.3 0.0 1.1 9.6 0.0 6.3 6 0 0 6 6 6 1 GAF domain EF-hand_1 PF00036.32 OQR93174.1 - 4.7e-05 22.6 2.5 0.02 14.4 0.4 3.3 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.6 OQR93174.1 - 0.0002 21.2 1.8 0.0012 18.7 0.2 3.1 2 1 1 3 3 3 1 EF-hand domain pair EF-hand_5 PF13202.6 OQR93174.1 - 0.16 11.5 2.2 5.4 6.7 0.2 3.7 3 0 0 3 3 3 0 EF hand IQ PF00612.27 OQR93175.1 - 3.4e-11 41.9 17.4 0.027 14.3 0.0 4.6 4 0 0 4 4 4 4 IQ calmodulin-binding motif TSC22 PF01166.18 OQR93175.1 - 0.15 12.4 7.0 2.5 8.5 1.2 3.3 2 0 0 2 2 2 0 TSC-22/dip/bun family Peptidase_U4 PF03419.13 OQR93175.1 - 0.18 11.1 0.7 0.36 10.1 0.7 1.4 1 0 0 1 1 1 0 Sporulation factor SpoIIGA Pkinase PF00069.25 OQR93176.1 - 1.1e-61 208.5 0.0 6e-61 206.1 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Tubulin PF00091.25 OQR93176.1 - 5.9e-54 183.3 0.0 1.3e-53 182.1 0.0 1.6 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Pkinase_Tyr PF07714.17 OQR93176.1 - 1.9e-31 109.3 0.2 7.2e-26 91.0 0.0 2.4 1 1 1 2 2 2 2 Protein tyrosine kinase His_Phos_1 PF00300.22 OQR93176.1 - 6.5e-30 104.3 2.1 6.5e-30 104.3 2.1 2.0 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) NAD_kinase PF01513.21 OQR93176.1 - 8.1e-16 58.1 0.0 1.9e-15 56.8 0.0 1.6 1 0 0 1 1 1 1 ATP-NAD kinase Misat_Tub_SegII PF10644.9 OQR93176.1 - 0.0037 17.6 0.0 0.01 16.1 0.0 1.8 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.6 OQR93176.1 - 0.0093 15.7 0.0 0.021 14.5 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain DAGK_cat PF00781.24 OQR93176.1 - 0.014 15.0 0.0 0.044 13.4 0.0 1.9 1 0 0 1 1 1 0 Diacylglycerol kinase catalytic domain Haspin_kinase PF12330.8 OQR93176.1 - 0.028 13.4 0.2 0.049 12.6 0.2 1.3 1 0 0 1 1 1 0 Haspin like kinase domain Tubulin_C PF03953.17 OQR93176.1 - 0.071 13.3 0.3 0.21 11.8 0.0 1.9 2 0 0 2 2 2 0 Tubulin C-terminal domain Tubulin_2 PF13809.6 OQR93176.1 - 0.099 11.8 0.0 0.17 11.0 0.0 1.3 1 0 0 1 1 1 0 Tubulin like APH PF01636.23 OQR93176.1 - 0.2 11.6 3.6 2.4 8.0 0.0 3.0 3 0 0 3 3 3 0 Phosphotransferase enzyme family SH3BGR PF04908.15 OQR93177.1 - 0.0011 19.1 0.5 0.0025 18.0 0.5 1.6 1 1 0 1 1 1 1 SH3-binding, glutamic acid-rich protein Glutaredoxin PF00462.24 OQR93177.1 - 0.11 12.7 0.0 0.21 11.8 0.0 1.4 1 0 0 1 1 1 0 Glutaredoxin MIP PF00230.20 OQR93178.1 - 1.3e-39 136.3 11.4 1.5e-39 136.0 11.4 1.1 1 0 0 1 1 1 1 Major intrinsic protein ATP-synt_J PF04911.12 OQR93178.1 - 1.9 8.1 6.0 6.2 6.5 0.4 3.3 2 1 1 3 3 3 0 ATP synthase j chain Peptidase_S28 PF05577.12 OQR93179.1 - 2.9e-64 217.5 0.0 3.9e-64 217.0 0.0 1.2 1 0 0 1 1 1 1 Serine carboxypeptidase S28 LRR_8 PF13855.6 OQR93179.1 - 4.7e-17 61.5 18.6 1.7e-08 34.1 0.4 3.7 3 0 0 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 OQR93179.1 - 4.3e-15 55.6 13.4 0.0033 17.8 0.0 5.1 5 0 0 5 5 4 4 Leucine Rich repeats (2 copies) Peptidase_S37 PF05576.11 OQR93179.1 - 0.00011 21.0 0.2 0.00022 20.0 0.2 1.4 1 0 0 1 1 1 1 PS-10 peptidase S37 Hydrolase_4 PF12146.8 OQR93179.1 - 0.00012 21.4 0.1 0.00023 20.5 0.1 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 OQR93179.1 - 0.005 16.5 0.2 0.013 15.2 0.1 1.7 2 0 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 OQR93179.1 - 0.012 15.1 0.1 0.029 13.9 0.1 1.6 2 0 0 2 2 2 0 Prolyl oligopeptidase family Abhydrolase_6 PF12697.7 OQR93179.1 - 0.024 15.3 1.1 0.13 12.8 1.1 2.1 1 1 0 1 1 1 0 Alpha/beta hydrolase family LRR_5 PF13306.6 OQR93179.1 - 0.041 13.8 0.0 0.095 12.7 0.0 1.5 1 0 0 1 1 1 0 BspA type Leucine rich repeat region (6 copies) LRR_1 PF00560.33 OQR93179.1 - 2.9 8.8 18.7 56 4.9 0.7 7.3 6 1 1 7 7 7 0 Leucine Rich Repeat LRR_6 PF13516.6 OQR93179.1 - 8.9 6.7 9.6 34 4.9 0.0 4.9 6 0 0 6 6 6 0 Leucine Rich repeat PH PF00169.29 OQR93180.1 - 4.8e-10 39.9 1.7 1.1e-09 38.7 1.7 1.6 1 0 0 1 1 1 1 PH domain PH_8 PF15409.6 OQR93180.1 - 2e-05 24.8 1.2 2e-05 24.8 1.2 1.5 2 0 0 2 2 2 1 Pleckstrin homology domain PH_13 PF16652.5 OQR93180.1 - 0.0049 16.7 0.4 0.0049 16.7 0.4 1.5 2 0 0 2 2 2 1 Pleckstrin homology domain PH_10 PF15411.6 OQR93180.1 - 0.12 12.7 0.2 0.12 12.7 0.2 2.0 2 0 0 2 2 2 0 Pleckstrin homology domain PH_11 PF15413.6 OQR93180.1 - 0.96 9.9 12.1 4.6 7.7 3.0 2.8 2 1 0 3 3 3 0 Pleckstrin homology domain zf-RING_2 PF13639.6 OQR93181.1 - 6.3e-10 39.2 9.5 6.3e-10 39.2 9.5 2.6 2 0 0 2 2 2 1 Ring finger domain Med26 PF08711.11 OQR93181.1 - 6.5e-09 35.7 0.0 1.9e-08 34.2 0.0 1.9 1 0 0 1 1 1 1 TFIIS helical bundle-like domain zf-C3HC4_2 PF13923.6 OQR93181.1 - 1.1e-06 28.3 9.2 1.1e-06 28.3 9.2 2.3 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 OQR93181.1 - 1.4e-06 27.9 7.7 1.4e-06 27.9 7.7 2.2 2 0 0 2 2 2 1 RING-like zinc finger zf-rbx1 PF12678.7 OQR93181.1 - 1.5e-06 28.4 6.5 1.5e-06 28.4 6.5 2.6 2 0 0 2 2 2 1 RING-H2 zinc finger domain PHD PF00628.29 OQR93181.1 - 8.7e-06 25.5 6.5 8.7e-06 25.5 6.5 2.9 2 1 0 2 2 2 1 PHD-finger zf-C3HC4 PF00097.25 OQR93181.1 - 0.00056 19.7 7.5 0.00056 19.7 7.5 2.5 2 1 1 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 OQR93181.1 - 0.0027 17.7 4.0 0.0027 17.7 4.0 2.1 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.6 OQR93181.1 - 0.0042 16.9 9.7 0.0042 16.9 9.7 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OQR93181.1 - 0.011 15.7 7.4 0.011 15.7 7.4 3.1 2 1 1 3 3 3 0 RING-type zinc-finger zf-RING_5 PF14634.6 OQR93181.1 - 0.016 15.1 8.5 0.016 15.1 8.5 2.3 3 0 0 3 3 2 0 zinc-RING finger domain zf-RING_4 PF14570.6 OQR93181.1 - 0.03 14.1 6.9 0.081 12.7 6.9 1.8 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-HC5HC2H PF13771.6 OQR93181.1 - 0.11 12.7 19.6 0.092 13.0 2.7 3.0 1 1 0 2 2 2 0 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.6 OQR93181.1 - 1.3 9.2 18.2 19 5.5 8.2 2.8 1 1 1 2 2 2 0 PHD-zinc-finger like domain SAYSvFN PF10260.9 OQR93182.1 - 1.1e-15 57.3 0.0 2.4e-15 56.2 0.0 1.6 1 1 0 1 1 1 1 Uncharacterized conserved domain (SAYSvFN) MPP6 PF10175.9 OQR93182.1 - 0.0078 16.7 2.9 0.0096 16.4 2.9 1.1 1 0 0 1 1 1 1 M-phase phosphoprotein 6 TLP-20 PF06088.11 OQR93182.1 - 0.017 15.0 0.1 0.019 14.8 0.1 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) Cwf_Cwc_15 PF04889.12 OQR93182.1 - 0.028 14.2 8.0 0.033 13.9 8.0 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DNA_pol_phi PF04931.13 OQR93182.1 - 0.27 9.3 8.1 0.34 9.0 8.1 1.1 1 0 0 1 1 1 0 DNA polymerase phi Mg_trans_NIPA PF05653.14 OQR93183.1 - 8.1e-38 130.2 18.7 3.6e-24 85.4 6.0 2.2 2 0 0 2 2 2 2 Magnesium transporter NIPA DnaJ_C PF01556.18 OQR93183.1 - 3.7e-29 101.7 0.1 6.6e-29 100.9 0.1 1.4 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 OQR93183.1 - 1.6e-28 98.6 1.0 3.6e-28 97.5 1.0 1.6 1 0 0 1 1 1 1 DnaJ domain FYVE PF01363.21 OQR93183.1 - 2.5e-16 59.5 9.5 6.5e-16 58.2 9.5 1.7 1 0 0 1 1 1 1 FYVE zinc finger GAF PF01590.26 OQR93183.1 - 0.00011 22.8 0.1 0.00026 21.6 0.1 1.7 1 0 0 1 1 1 1 GAF domain TMEM234 PF10639.9 OQR93183.1 - 0.0026 17.8 0.8 0.0026 17.8 0.8 1.9 2 0 0 2 2 2 1 Putative transmembrane family 234 Herpes_LMP1 PF05297.11 OQR93183.1 - 0.0076 15.5 0.2 0.014 14.6 0.2 1.3 1 0 0 1 1 1 1 Herpesvirus latent membrane protein 1 (LMP1) 7TM_GPCR_Sri PF10327.9 OQR93183.1 - 0.062 12.5 6.0 0.022 14.0 3.2 1.7 2 0 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Sri Exonuc_VII_L PF02601.15 OQR93183.1 - 1.9 8.0 7.1 9.5 5.7 0.2 2.3 2 0 0 2 2 2 0 Exonuclease VII, large subunit BPL_LplA_LipB PF03099.19 OQR93184.1 - 7.5e-16 58.2 0.0 1.4e-15 57.4 0.0 1.5 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family RNA_pol_Rpc82 PF05645.13 OQR93184.1 - 1.2e-09 38.3 1.9 5.4e-07 29.6 0.5 3.6 2 1 0 2 2 2 1 RNA polymerase III subunit RPC82 HTH_9 PF08221.11 OQR93184.1 - 4.5e-08 33.1 1.8 3.4e-05 23.9 0.5 3.4 3 0 0 3 3 3 2 RNA polymerase III subunit RPC82 helix-turn-helix domain TFIIE_alpha PF02002.17 OQR93184.1 - 1.4e-05 24.9 4.6 7.3e-05 22.6 0.4 2.8 3 0 0 3 3 3 1 TFIIE alpha subunit BPL_C PF02237.17 OQR93184.1 - 0.00017 21.4 0.0 0.00034 20.5 0.0 1.5 1 0 0 1 1 1 1 Biotin protein ligase C terminal domain Nucleocapsid-N PF11030.8 OQR93184.1 - 0.14 12.1 0.0 0.34 10.8 0.0 1.6 2 0 0 2 2 2 0 Nucleocapsid protein N Ofd1_CTDD PF10637.9 OQR93185.1 - 1.1e-61 208.4 0.0 3.7e-58 196.9 0.0 2.1 2 0 0 2 2 2 2 Oxoglutarate and iron-dependent oxygenase degradation C-term 2OG-FeII_Oxy_4 PF13661.6 OQR93185.1 - 2.1e-23 82.8 0.0 1.1e-22 80.4 0.0 2.1 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.6 OQR93185.1 - 1.8e-13 51.1 0.0 3.6e-13 50.2 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DUF3644 PF12358.8 OQR93185.1 - 0.14 12.7 0.0 0.35 11.4 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3644) DnaJ PF00226.31 OQR93186.1 - 2.3e-24 85.3 5.1 4.5e-24 84.3 5.1 1.5 1 0 0 1 1 1 1 DnaJ domain Thioredoxin PF00085.20 OQR93186.1 - 6.7e-10 38.9 0.2 3.8e-06 26.8 0.0 2.3 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_6 PF13848.6 OQR93186.1 - 1.4e-05 25.1 0.1 0.16 11.9 0.0 2.3 2 0 0 2 2 2 2 Thioredoxin-like domain Calsequestrin PF01216.17 OQR93186.1 - 0.084 11.9 3.8 1.4 7.8 0.0 2.9 3 0 0 3 3 3 0 Calsequestrin OST3_OST6 PF04756.13 OQR93186.1 - 0.15 11.4 0.0 0.37 10.1 0.0 1.7 1 1 1 2 2 2 0 OST3 / OST6 family, transporter family TPR_2 PF07719.17 OQR93187.1 - 6.6e-08 32.1 0.1 0.00016 21.5 0.4 3.2 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.6 OQR93187.1 - 2e-06 28.2 1.4 7.2e-06 26.4 0.0 2.5 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 OQR93187.1 - 6.6e-06 26.7 0.8 2.4e-05 24.9 0.2 2.4 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 OQR93187.1 - 9.3e-05 22.9 5.5 0.0035 18.0 0.3 4.2 2 1 2 4 4 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 OQR93187.1 - 0.0003 21.0 8.8 0.0023 18.2 0.8 2.7 1 1 3 4 4 4 2 Tetratricopeptide repeat ANAPC3 PF12895.7 OQR93187.1 - 0.0012 19.0 1.0 0.0034 17.6 0.3 2.0 1 1 1 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_1 PF00515.28 OQR93187.1 - 0.0012 18.5 0.4 0.024 14.5 0.1 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.6 OQR93187.1 - 0.0013 18.9 0.1 6.1 7.5 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.6 OQR93187.1 - 0.022 15.4 0.0 8.9 7.2 0.0 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.6 OQR93187.1 - 0.062 13.2 0.1 0.24 11.3 0.1 2.1 1 0 0 1 1 1 0 Tetratricopeptide repeat YccV-like PF08755.11 OQR93187.1 - 0.08 13.5 0.3 0.73 10.4 0.3 2.5 1 1 0 1 1 1 0 Hemimethylated DNA-binding protein YccV like TPR_9 PF13371.6 OQR93187.1 - 0.08 13.1 4.0 0.15 12.2 0.4 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF5112 PF17139.4 OQR93187.1 - 0.082 12.4 0.1 0.13 11.7 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5112) DUF4398 PF14346.6 OQR93187.1 - 5.3 7.7 8.2 33 5.2 8.2 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4398) TPR_2 PF07719.17 OQR93188.1 - 2.2e-05 24.2 0.2 0.69 10.2 0.1 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.6 OQR93188.1 - 0.00032 20.9 0.4 0.028 14.8 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.28 OQR93188.1 - 0.00078 19.2 0.6 6.4 6.8 0.2 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 OQR93188.1 - 0.0011 18.6 0.0 0.13 12.0 0.0 3.1 3 0 0 3 3 3 1 TPR repeat TPR_8 PF13181.6 OQR93188.1 - 0.0013 18.7 0.4 0.14 12.4 0.5 2.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 OQR93188.1 - 0.0072 16.8 0.0 0.022 15.3 0.0 1.8 2 0 0 2 2 2 1 Tetratricopeptide repeat DUF2225 PF09986.9 OQR93188.1 - 0.043 13.6 0.0 0.044 13.5 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2225) LMF1 PF06762.14 OQR93189.1 - 2.2e-110 369.8 9.8 2.9e-110 369.4 9.8 1.1 1 0 0 1 1 1 1 Lipase maturation factor HMMR_C PF15908.5 OQR93189.1 - 0.00011 22.6 3.2 0.00011 22.6 3.2 2.4 1 1 0 2 2 2 1 Hyaluronan mediated motility receptor C-terminal Cnn_1N PF07989.11 OQR93189.1 - 0.065 13.4 16.4 0.35 11.0 0.1 3.4 3 0 0 3 3 3 0 Centrosomin N-terminal motif 1 UPF0242 PF06785.11 OQR93189.1 - 0.33 11.1 18.1 0.47 10.5 3.0 2.7 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus DUF1336 PF07059.12 OQR93190.1 - 1.2e-48 166.1 0.0 2.2e-48 165.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1336) PH PF00169.29 OQR93190.1 - 1.6e-17 63.9 0.0 4.9e-17 62.3 0.0 1.9 1 0 0 1 1 1 1 PH domain PX PF00787.24 OQR93190.1 - 1.7e-05 24.8 0.0 3.7e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 PX domain PH_11 PF15413.6 OQR93190.1 - 0.00014 22.2 8.7 0.001 19.5 6.5 3.1 2 1 0 2 2 2 1 Pleckstrin homology domain PH_8 PF15409.6 OQR93190.1 - 0.00025 21.3 0.1 0.00095 19.4 0.1 2.0 1 1 0 1 1 1 1 Pleckstrin homology domain Cpta_toxin PF07254.12 OQR93190.1 - 0.075 13.0 2.2 1.9 8.5 0.1 2.3 2 0 0 2 2 2 0 Membrane-bound toxin component of toxin-antitoxin system PH_9 PF15410.6 OQR93190.1 - 0.68 10.3 3.0 8.6 6.8 1.4 2.9 2 1 0 2 2 2 0 Pleckstrin homology domain Nucleoside_tran PF01733.18 OQR93191.1 - 5.2e-40 137.7 18.6 5.2e-40 137.7 18.6 2.7 1 1 1 2 2 2 1 Nucleoside transporter 60KD_IMP PF02096.20 OQR93191.1 - 3.6 7.5 9.9 5.2 6.9 0.2 3.5 3 1 1 4 4 4 0 60Kd inner membrane protein Pkinase PF00069.25 OQR93192.1 - 2.5e-52 177.8 0.0 4.3e-50 170.5 0.0 2.2 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQR93192.1 - 6.3e-24 84.6 0.0 2e-23 83.0 0.0 1.9 2 1 0 2 2 2 1 Protein tyrosine kinase RGS PF00615.19 OQR93192.1 - 3.7e-09 36.9 0.2 8.3e-08 32.5 0.0 2.6 3 0 0 3 3 3 1 Regulator of G protein signaling domain Haspin_kinase PF12330.8 OQR93192.1 - 0.017 14.1 0.1 0.028 13.4 0.1 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Pkinase_fungal PF17667.1 OQR93192.1 - 0.072 11.9 0.0 0.77 8.5 0.0 2.0 2 0 0 2 2 2 0 Fungal protein kinase DUF2890 PF11081.8 OQR93192.1 - 0.089 12.9 0.2 18 5.4 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2890) FBD PF08387.10 OQR93192.1 - 0.1 12.5 0.0 0.23 11.4 0.0 1.5 1 0 0 1 1 1 0 FBD zf-CCHC_5 PF14787.6 OQR93192.1 - 0.13 12.0 0.1 0.27 11.0 0.1 1.5 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger DEAD PF00270.29 OQR93193.1 - 1e-36 126.4 0.2 1.6e-36 125.7 0.2 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OQR93193.1 - 1.4e-24 86.6 0.0 3.7e-24 85.2 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 OQR93193.1 - 5.2e-06 26.6 0.0 1.5e-05 25.0 0.0 1.7 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DUF2399 PF09664.10 OQR93193.1 - 0.091 12.7 0.0 0.32 10.9 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function C-terminus (DUF2399) CMS1 PF14617.6 OQR93193.1 - 0.096 12.0 0.2 0.34 10.2 0.0 1.8 2 0 0 2 2 2 0 U3-containing 90S pre-ribosomal complex subunit DUF5586 PF17824.1 OQR93194.1 - 0.036 13.2 0.1 0.047 12.8 0.1 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5586) Evf PF18270.1 OQR93194.1 - 0.04 13.3 0.2 0.059 12.8 0.2 1.3 1 0 0 1 1 1 0 Virulence factor Evf BCDHK_Adom3 PF10436.9 OQR93205.1 - 1.1e-28 100.1 0.2 1.6e-28 99.6 0.2 1.2 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 OQR93205.1 - 2.4e-08 34.5 0.0 1.5e-07 31.9 0.0 2.1 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 OQR93205.1 - 0.056 13.3 0.0 0.13 12.1 0.0 1.6 1 1 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Transglut_core PF01841.19 OQR93206.1 - 0.018 15.5 0.0 0.069 13.6 0.0 2.1 1 1 0 1 1 1 0 Transglutaminase-like superfamily SpoU_sub_bind PF08032.12 OQR93206.1 - 0.15 12.3 0.0 0.49 10.7 0.0 1.9 1 0 0 1 1 1 0 RNA 2'-O ribose methyltransferase substrate binding Lactamase_B_2 PF12706.7 OQR93207.1 - 7.3e-34 117.1 0.0 1e-33 116.6 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 OQR93207.1 - 3.5e-14 53.0 0.0 5.1e-14 52.5 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 OQR93207.1 - 0.038 14.0 0.1 0.27 11.2 0.0 2.1 2 0 0 2 2 2 0 Metallo-beta-lactamase superfamily Dor1 PF04124.12 OQR93210.1 - 2.4e-52 177.7 5.9 3.8e-52 177.1 5.9 1.3 1 0 0 1 1 1 1 Dor1-like family Vps54_N PF10475.9 OQR93210.1 - 0.00064 19.1 3.3 0.0012 18.1 3.3 1.4 1 0 0 1 1 1 1 Vacuolar-sorting protein 54, of GARP complex Zw10 PF06248.13 OQR93210.1 - 0.0012 17.5 3.6 0.0025 16.4 3.6 1.5 1 0 0 1 1 1 1 Centromere/kinetochore Zw10 Sec5 PF15469.6 OQR93210.1 - 0.0075 16.1 1.4 0.02 14.7 1.4 1.7 1 0 0 1 1 1 1 Exocyst complex component Sec5 EzrA PF06160.12 OQR93210.1 - 0.012 13.8 2.1 0.02 13.1 2.1 1.2 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA SAT PF16073.5 OQR93210.1 - 1.2 8.8 5.6 3.4 7.3 1.5 2.5 2 0 0 2 2 2 0 Starter unit:ACP transacylase in aflatoxin biosynthesis Myotub-related PF06602.14 OQR93211.1 - 1.4e-113 379.4 0.0 5.3e-113 377.5 0.0 1.8 2 0 0 2 2 2 1 Myotubularin-like phosphatase domain Y_phosphatase PF00102.27 OQR93211.1 - 0.02 14.5 0.0 0.034 13.7 0.0 1.3 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 OQR93211.1 - 0.1 12.5 0.0 0.22 11.5 0.0 1.5 1 0 0 1 1 1 0 Tyrosine phosphatase family UQ_con PF00179.26 OQR93212.1 - 2.8e-50 169.6 0.0 3.2e-50 169.4 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 OQR93212.1 - 0.0043 16.7 0.0 0.0055 16.4 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 OQR93212.1 - 0.035 14.4 0.0 0.053 13.8 0.0 1.3 1 0 0 1 1 1 0 RWD domain UEV PF05743.13 OQR93212.1 - 0.075 12.9 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 UEV domain DUF676 PF05057.14 OQR93242.1 - 2.6e-28 99.1 0.0 4.1e-27 95.1 0.0 2.1 2 0 0 2 2 2 1 Putative serine esterase (DUF676) Palm_thioest PF02089.15 OQR93242.1 - 0.004 17.0 0.0 0.0082 16.0 0.0 1.4 1 0 0 1 1 1 1 Palmitoyl protein thioesterase PGAP1 PF07819.13 OQR93242.1 - 0.01 15.6 0.0 0.021 14.5 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein LCAT PF02450.15 OQR93242.1 - 0.084 12.0 0.0 0.13 11.4 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase Abhydrolase_6 PF12697.7 OQR93242.1 - 0.098 13.2 0.1 0.33 11.5 0.0 1.9 1 1 0 1 1 1 0 Alpha/beta hydrolase family Mce4_CUP1 PF11887.8 OQR93243.1 - 0.02 14.3 0.6 0.041 13.3 0.6 1.4 1 0 0 1 1 1 0 Cholesterol uptake porter CUP1 of Mce4, putative BST2 PF16716.5 OQR93243.1 - 3.6 8.3 10.2 0.39 11.3 0.3 3.0 2 1 1 3 3 3 0 Bone marrow stromal antigen 2 DUF2804 PF10974.8 OQR93244.1 - 1.1e-49 169.8 0.7 1.4e-49 169.4 0.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2804) Pyr_redox_2 PF07992.14 OQR93245.1 - 4.2e-55 187.1 0.1 1e-53 182.5 0.1 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 OQR93245.1 - 3.7e-32 110.8 0.1 7.1e-32 109.9 0.1 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 OQR93245.1 - 1.1e-20 73.9 0.8 1.6e-16 60.6 0.0 2.9 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 OQR93245.1 - 6.2e-13 48.7 0.2 1.4e-08 34.4 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 OQR93245.1 - 1.1e-07 31.6 0.2 6.3e-07 29.1 0.8 1.9 3 0 0 3 3 3 1 FAD dependent oxidoreductase K_oxygenase PF13434.6 OQR93245.1 - 7.2e-05 22.1 0.0 0.0024 17.1 0.0 2.3 1 1 1 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) HI0933_like PF03486.14 OQR93245.1 - 0.00025 19.9 0.4 0.0063 15.3 0.5 2.7 3 0 0 3 3 3 1 HI0933-like protein FAD_binding_2 PF00890.24 OQR93245.1 - 0.00026 20.2 1.5 0.00063 18.9 1.5 1.6 1 0 0 1 1 1 1 FAD binding domain AlaDh_PNT_C PF01262.21 OQR93245.1 - 0.00037 19.8 1.1 0.29 10.4 0.0 2.3 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_7 PF13241.6 OQR93245.1 - 0.0016 18.8 0.1 0.65 10.5 0.0 2.4 2 0 0 2 2 2 1 Putative NAD(P)-binding NAD_binding_8 PF13450.6 OQR93245.1 - 0.002 18.3 0.2 0.002 18.3 0.2 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 OQR93245.1 - 0.0055 15.8 1.2 0.0055 15.8 1.2 1.7 2 0 0 2 2 2 1 Glucose inhibited division protein A DAO PF01266.24 OQR93245.1 - 0.0074 15.9 4.5 0.019 14.6 0.1 2.9 2 1 1 3 3 3 1 FAD dependent oxidoreductase 2-Hacid_dh_C PF02826.19 OQR93245.1 - 0.011 15.1 1.5 4.1 6.7 0.0 3.2 3 0 0 3 3 3 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.18 OQR93245.1 - 0.024 14.5 1.3 0.12 12.2 0.0 2.2 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Thi4 PF01946.17 OQR93245.1 - 0.047 12.9 0.5 0.097 11.9 0.5 1.4 1 0 0 1 1 1 0 Thi4 family FAD_binding_3 PF01494.19 OQR93245.1 - 5.6 6.1 5.1 2.3 7.4 0.5 2.0 2 0 0 2 2 2 0 FAD binding domain zf-RING_2 PF13639.6 OQR93246.1 - 4.9e-12 46.0 5.3 4.9e-12 46.0 5.3 2.2 2 0 0 2 2 2 1 Ring finger domain PX PF00787.24 OQR93246.1 - 3e-08 33.6 1.7 5e-08 32.9 1.7 1.3 1 0 0 1 1 1 1 PX domain zf-rbx1 PF12678.7 OQR93246.1 - 8.4e-08 32.4 14.1 1.4e-07 31.7 10.3 2.9 2 1 0 2 2 2 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 OQR93246.1 - 2.9e-07 30.5 4.3 2.9e-07 30.5 4.3 2.1 2 1 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_11 PF17123.5 OQR93246.1 - 4.6e-07 29.5 2.6 1.1e-06 28.3 2.6 1.7 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_UBOX PF13445.6 OQR93246.1 - 7.8e-07 29.0 2.6 1.9e-06 27.8 2.6 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 OQR93246.1 - 2e-06 27.6 3.6 2e-06 27.6 3.6 2.2 2 1 0 2 2 2 1 zinc-RING finger domain zf-C3HC4 PF00097.25 OQR93246.1 - 2.5e-06 27.3 3.3 2.5e-06 27.3 3.3 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 OQR93246.1 - 2.3e-05 24.1 7.5 0.0001 22.1 7.5 2.2 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 OQR93246.1 - 8.1e-05 22.4 1.5 8.1e-05 22.4 1.5 2.8 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 OQR93246.1 - 0.00034 20.4 6.8 0.017 15.0 7.5 2.6 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 Zn_ribbon_17 PF17120.5 OQR93246.1 - 0.0018 17.9 3.5 0.0018 17.9 3.5 2.6 3 0 0 3 3 3 1 Zinc-ribbon, C4HC2 type zf-RING_4 PF14570.6 OQR93246.1 - 0.16 11.8 7.0 0.075 12.8 3.8 2.0 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain FANCL_C PF11793.8 OQR93246.1 - 3.1 8.0 11.3 4.4 7.5 7.6 3.0 2 1 0 2 2 2 0 FANCL C-terminal domain zf-C3HC4_4 PF15227.6 OQR93246.1 - 6.8 6.9 11.7 0.67 10.2 2.5 3.1 3 0 0 3 3 3 0 zinc finger of C3HC4-type, RING DUF676 PF05057.14 OQR93247.1 - 1.2e-29 103.5 0.0 2.2e-28 99.3 0.0 2.1 2 0 0 2 2 2 1 Putative serine esterase (DUF676) Palm_thioest PF02089.15 OQR93247.1 - 0.00014 21.8 0.0 0.00024 21.1 0.0 1.3 1 0 0 1 1 1 1 Palmitoyl protein thioesterase PGAP1 PF07819.13 OQR93247.1 - 0.087 12.5 0.0 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein Lipase_3 PF01764.25 OQR93247.1 - 0.099 12.5 0.0 0.18 11.7 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) LCAT PF02450.15 OQR93247.1 - 0.15 11.2 0.0 0.23 10.6 0.0 1.1 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase FAP206 PF12018.8 OQR93249.1 - 4.8e-72 242.8 1.1 6.3e-72 242.4 0.2 1.7 2 0 0 2 2 2 1 Domain of unknown function DUF2120 PF09893.9 OQR93249.1 - 0.026 14.6 0.9 0.38 10.8 0.0 3.0 3 0 0 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2120) KN_motif PF12075.8 OQR93249.1 - 0.19 11.6 0.1 0.4 10.5 0.1 1.5 1 0 0 1 1 1 0 KN motif Fib_alpha PF08702.10 OQR93249.1 - 4.4 7.5 7.1 32 4.7 3.8 2.9 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family Cellulase PF00150.18 OQR93252.1 - 9.6e-86 287.7 10.0 1.6e-28 100.0 0.1 3.3 3 0 0 3 3 3 3 Cellulase (glycosyl hydrolase family 5) Ank_2 PF12796.7 OQR93252.1 - 2.8e-54 181.7 14.3 3.2e-13 50.1 0.3 6.7 1 1 4 6 6 6 6 Ankyrin repeats (3 copies) Ank PF00023.30 OQR93252.1 - 4.3e-45 150.3 14.7 4.2e-06 26.9 0.0 12.8 12 1 0 12 12 12 9 Ankyrin repeat Ank_4 PF13637.6 OQR93252.1 - 6.1e-43 144.7 5.6 1.7e-08 34.9 0.0 8.9 5 2 2 8 8 8 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQR93252.1 - 1.7e-36 120.1 1.5 0.0016 18.8 0.0 12.1 11 1 1 12 12 12 7 Ankyrin repeat Ank_5 PF13857.6 OQR93252.1 - 1.3e-24 85.9 10.4 0.00081 19.7 0.0 9.7 3 2 7 10 10 10 8 Ankyrin repeats (many copies) Clathrin_bdg PF15045.6 OQR93252.1 - 1.1e-07 31.7 0.0 0.68 10.0 0.0 3.7 3 0 0 3 3 3 3 Clathrin-binding box of Aftiphilin, vesicle trafficking LapA_dom PF06305.11 OQR93252.1 - 0.04 13.7 2.4 13 5.7 0.0 3.4 3 0 0 3 3 3 0 Lipopolysaccharide assembly protein A domain gpW PF02831.15 OQR93252.1 - 0.086 12.8 3.2 30 4.6 0.1 3.6 3 0 0 3 3 3 0 gpW PRANC PF09372.10 OQR93252.1 - 0.15 12.4 14.8 23 5.4 0.4 5.7 4 2 2 6 6 6 0 PRANC domain SARAF PF06682.12 OQR93252.1 - 0.33 10.6 1.0 84 2.7 0.0 3.0 3 0 0 3 3 3 0 SOCE-associated regulatory factor of calcium homoeostasis PMP1_2 PF08114.11 OQR93252.1 - 3.8 7.3 8.7 17 5.2 0.1 3.5 3 0 0 3 3 3 0 ATPase proteolipid family MIR PF02815.19 OQR93253.1 - 7.7e-09 35.7 0.0 1.3e-08 34.9 0.0 1.4 1 0 0 1 1 1 1 MIR domain Rad51 PF08423.11 OQR93254.1 - 8.9e-30 103.8 0.0 1.1e-29 103.5 0.0 1.1 1 0 0 1 1 1 1 Rad51 ATPase PF06745.13 OQR93254.1 - 7.7e-08 32.0 0.7 2.8e-07 30.1 0.7 1.9 1 1 0 1 1 1 1 KaiC AAA_25 PF13481.6 OQR93254.1 - 7.1e-05 22.5 0.0 0.00011 21.9 0.0 1.2 1 0 0 1 1 1 1 AAA domain RecA PF00154.21 OQR93254.1 - 0.0021 17.6 0.3 0.45 9.9 0.0 2.2 1 1 1 2 2 2 2 recA bacterial DNA recombination protein ABC_tran PF00005.27 OQR93254.1 - 0.0041 17.6 0.0 0.01 16.4 0.0 1.9 1 1 0 1 1 1 1 ABC transporter NACHT PF05729.12 OQR93254.1 - 0.0077 16.2 0.0 0.015 15.2 0.0 1.4 1 0 0 1 1 1 1 NACHT domain AAA_18 PF13238.6 OQR93254.1 - 0.052 14.1 0.0 0.3 11.6 0.0 2.2 1 1 0 1 1 1 0 AAA domain DUF2306 PF10067.9 OQR93255.1 - 4.9e-17 62.5 14.3 3.1e-12 46.9 3.2 2.0 2 0 0 2 2 2 2 Predicted membrane protein (DUF2306) DUF4401 PF14351.6 OQR93255.1 - 0.012 15.0 3.2 0.017 14.4 3.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4401) DUF420 PF04238.12 OQR93255.1 - 0.012 15.9 12.6 0.047 14.0 0.2 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF420) 7TMR-DISM_7TM PF07695.11 OQR93255.1 - 0.52 10.2 5.2 0.49 10.3 0.4 2.4 1 1 2 3 3 3 0 7TM diverse intracellular signalling DUF3995 PF13160.6 OQR93255.1 - 3 8.2 11.6 2.3 8.6 1.8 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF3995) ADP_PFK_GK PF04587.15 OQR93268.1 - 2.5e-101 339.4 0.0 2.9e-101 339.1 0.0 1.0 1 0 0 1 1 1 1 ADP-specific Phosphofructokinase/Glucokinase conserved region LRR_6 PF13516.6 OQR93269.1 - 0.0027 17.6 0.0 1.5 9.0 0.0 2.8 2 0 0 2 2 2 2 Leucine Rich repeat DUF5305 PF17231.2 OQR93270.1 - 0.0014 18.1 0.0 0.002 17.6 0.0 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF5305) EGF_2 PF07974.13 OQR93270.1 - 0.0055 17.0 15.9 0.0055 17.0 15.9 4.2 5 1 0 5 5 5 2 EGF-like domain TMEM154 PF15102.6 OQR93270.1 - 0.0087 16.0 0.0 0.013 15.4 0.0 1.2 1 0 0 1 1 1 1 TMEM154 protein family DUF4381 PF14316.6 OQR93270.1 - 0.011 16.0 0.0 0.015 15.5 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) BatD PF13584.6 OQR93270.1 - 0.043 12.6 0.0 0.056 12.2 0.0 1.1 1 0 0 1 1 1 0 Oxygen tolerance EGF PF00008.27 OQR93270.1 - 0.049 14.0 9.9 0.049 14.0 9.9 4.5 4 1 1 5 5 5 0 EGF-like domain Cation_efflux PF01545.21 OQR93270.1 - 0.12 12.1 0.0 1.8 8.2 0.0 2.0 2 0 0 2 2 2 0 Cation efflux family DUF4366 PF14283.6 OQR93270.1 - 0.12 12.4 0.0 0.24 11.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) CALM_bind PF16025.5 OQR93271.1 - 1.5 9.3 5.3 5.1 7.6 5.3 1.9 1 1 0 1 1 1 0 Calcium-dependent calmodulin binding Vps5 PF09325.10 OQR93272.1 - 5.7e-37 127.5 3.3 7.7e-37 127.1 3.3 1.1 1 0 0 1 1 1 1 Vps5 C terminal like PX PF00787.24 OQR93272.1 - 4.6e-27 94.2 0.0 8.7e-27 93.4 0.0 1.5 1 0 0 1 1 1 1 PX domain BAR_3_WASP_bdg PF10456.9 OQR93272.1 - 0.00011 21.8 4.5 0.001 18.6 4.5 2.2 1 1 0 1 1 1 1 WASP-binding domain of Sorting nexin protein FAM92 PF06730.11 OQR93272.1 - 0.0015 18.0 3.3 0.007 15.8 1.9 2.1 2 0 0 2 2 2 1 FAM92 protein WD40 PF00400.32 OQR93273.1 - 5.5e-20 71.3 8.9 0.00079 20.2 0.0 7.0 8 0 0 8 8 8 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OQR93273.1 - 1.1e-11 44.8 0.3 0.018 15.3 0.0 5.5 2 2 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain ShlB PF03865.13 OQR93273.1 - 0.081 12.4 1.6 0.15 11.5 1.6 1.3 1 0 0 1 1 1 0 Haemolysin secretion/activation protein ShlB/FhaC/HecB EGF_2 PF07974.13 OQR93274.1 - 5.2e-05 23.5 40.3 0.00093 19.5 13.1 4.3 4 1 0 4 4 4 2 EGF-like domain EGF PF00008.27 OQR93274.1 - 7.2e-05 23.0 8.5 7.2e-05 23.0 8.5 3.6 3 0 0 3 3 3 1 EGF-like domain Herpes_BLLF1 PF05109.13 OQR93274.1 - 9.2e-05 20.6 16.5 0.00014 20.0 16.5 1.2 1 0 0 1 1 1 1 Herpes virus major outer envelope glycoprotein (BLLF1) hEGF PF12661.7 OQR93274.1 - 0.011 16.3 5.0 0.011 16.3 5.0 5.0 4 1 0 4 4 4 0 Human growth factor-like EGF cEGF PF12662.7 OQR93274.1 - 1.3 9.0 14.9 1.6 8.7 0.7 3.8 3 0 0 3 3 3 0 Complement Clr-like EGF-like OST3_OST6 PF04756.13 OQR93275.1 - 2.8e-62 210.7 0.0 3.5e-62 210.4 0.0 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Copper-fist PF00649.18 OQR93275.1 - 0.088 12.3 0.1 0.17 11.4 0.1 1.4 1 0 0 1 1 1 0 Copper fist DNA binding domain Spore_YabQ PF09578.10 OQR93275.1 - 0.22 11.7 8.6 2.2 8.6 2.0 2.5 2 0 0 2 2 2 0 Spore cortex protein YabQ (Spore_YabQ) ubiquitin PF00240.23 OQR93276.1 - 6.1e-09 35.5 0.1 1.9e-08 33.9 0.1 1.9 1 0 0 1 1 1 1 Ubiquitin family Glyco_hydro_63 PF03200.16 OQR93277.1 - 3.1e-137 458.3 0.4 3.6e-82 276.7 0.1 2.1 2 0 0 2 2 2 2 Glycosyl hydrolase family 63 C-terminal domain Glyco_hydro_63N PF16923.5 OQR93277.1 - 9.5e-33 114.2 0.5 1.6e-32 113.4 0.2 1.6 2 0 0 2 2 2 1 Glycosyl hydrolase family 63 N-terminal domain GDE_C PF06202.14 OQR93277.1 - 1.8e-07 30.4 0.0 4.7e-07 29.1 0.0 1.6 2 0 0 2 2 2 1 Amylo-alpha-1,6-glucosidase Glycos_transf_2 PF00535.26 OQR93278.1 - 3.2e-30 105.2 0.0 4.3e-30 104.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 OQR93278.1 - 2.2e-09 37.6 0.0 3e-09 37.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 OQR93278.1 - 0.004 16.7 0.0 0.0055 16.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Pneumo_ncap PF03246.13 OQR93278.1 - 0.032 13.0 0.1 0.043 12.6 0.1 1.1 1 0 0 1 1 1 0 Pneumovirus nucleocapsid protein F-box PF00646.33 OQR93279.1 - 3.9e-06 26.6 0.1 8.7e-06 25.5 0.1 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 OQR93279.1 - 0.0035 17.2 1.0 0.0067 16.3 0.1 2.1 2 0 0 2 2 2 1 F-box-like Adeno_Penton_B PF01686.17 OQR93279.1 - 0.018 13.5 0.1 0.023 13.2 0.1 1.0 1 0 0 1 1 1 0 Adenovirus penton base protein ACI44 PF15270.6 OQR93280.1 - 0.12 12.6 1.4 0.34 11.1 1.4 1.7 1 0 0 1 1 1 0 Metallo-carboxypeptidase inhibitor polyprenyl_synt PF00348.17 OQR93281.1 - 4e-62 209.6 0.0 4.8e-62 209.3 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase HTH_22 PF13309.6 OQR93281.1 - 0.029 14.4 0.1 0.14 12.3 0.0 2.0 2 0 0 2 2 2 0 HTH domain Flavodoxin_1 PF00258.25 OQR93293.1 - 1.1e-24 87.2 0.2 1.7e-24 86.7 0.2 1.3 1 0 0 1 1 1 1 Flavodoxin FAD_binding_1 PF00667.20 OQR93293.1 - 1.5e-19 70.4 0.1 2e-19 70.0 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.21 OQR93293.1 - 3.6e-07 30.8 0.0 1e-06 29.4 0.0 1.7 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Flavodoxin_5 PF12724.7 OQR93293.1 - 5.3e-05 23.5 0.0 0.038 14.2 0.0 2.4 1 1 0 2 2 2 2 Flavodoxin domain B56 PF01603.20 OQR93294.1 - 2.9e-99 332.9 0.1 3.7e-99 332.5 0.1 1.0 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) eIF-6 PF01912.18 OQR93295.1 - 1.1e-56 191.3 0.2 1.3e-56 191.2 0.2 1.0 1 0 0 1 1 1 1 eIF-6 family Pkinase PF00069.25 OQR93304.1 - 2e-13 50.3 0.0 2.8e-12 46.6 0.0 2.2 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQR93304.1 - 4e-06 26.3 0.0 1.4e-05 24.5 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase WD40 PF00400.32 OQR93305.1 - 1.9e-15 57.0 0.5 0.00081 20.2 0.0 6.4 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OQR93305.1 - 8.6e-11 42.0 0.0 0.22 11.9 0.0 6.0 1 1 4 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain Cytochrom_D1 PF02239.16 OQR93305.1 - 2.9e-08 32.7 0.0 5.5e-08 31.7 0.0 1.5 1 0 0 1 1 1 1 Cytochrome D1 heme domain CNH PF00780.22 OQR93305.1 - 0.097 12.3 0.0 1.6 8.3 0.0 2.3 2 1 0 2 2 2 0 CNH domain DUF5640 PF18692.1 OQR93305.1 - 0.15 12.1 0.0 0.54 10.3 0.0 1.9 1 0 0 1 1 1 0 Family of unknown function (DUF5640) ECH_1 PF00378.20 OQR93306.1 - 1.3e-63 214.7 0.1 1.5e-63 214.5 0.1 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 OQR93306.1 - 7.1e-30 104.6 0.4 6.1e-29 101.6 0.4 1.7 1 1 1 2 2 2 1 Enoyl-CoA hydratase/isomerase Elicitin PF00964.17 OQR93307.1 - 0.0023 18.0 2.3 0.0023 18.0 2.3 2.9 2 2 0 2 2 2 1 Elicitin PsbU PF06514.11 OQR93307.1 - 0.0039 17.1 0.0 0.0096 15.9 0.0 1.6 2 0 0 2 2 2 1 Photosystem II 12 kDa extrinsic protein (PsbU) DUF1690 PF07956.11 OQR93308.1 - 0.00088 19.7 5.2 0.006 17.0 5.0 2.0 1 1 0 1 1 1 1 Protein of Unknown function (DUF1690) CHCH PF06747.13 OQR93308.1 - 0.0091 16.1 2.7 0.017 15.2 2.7 1.5 1 0 0 1 1 1 1 CHCH domain PrpR_N PF06506.11 OQR93308.1 - 0.049 13.2 0.6 8.7 5.9 0.1 2.2 1 1 1 2 2 2 0 Propionate catabolism activator Cullin PF00888.22 OQR93309.1 - 4.9e-174 580.4 6.4 6.3e-174 580.0 6.4 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 OQR93309.1 - 1.6e-25 88.9 2.2 2.9e-25 88.1 0.8 2.3 2 0 0 2 2 2 1 Cullin protein neddylation domain ERG4_ERG24 PF01222.17 OQR93310.1 - 5.2e-76 256.1 12.0 6.1e-76 255.9 12.0 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.12 OQR93310.1 - 0.0071 15.9 0.2 0.0071 15.9 0.2 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1295) Pkinase PF00069.25 OQR93311.1 - 1.3e-12 47.7 0.0 1.5e-12 47.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQR93311.1 - 4.8e-11 42.4 0.0 5.4e-11 42.3 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase LRR_4 PF12799.7 OQR93312.1 - 3.1e-23 81.5 13.0 1.6e-05 25.1 0.0 5.6 5 0 0 5 5 5 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 OQR93312.1 - 2.7e-17 62.3 16.0 8.6e-05 22.2 2.2 5.3 2 1 2 5 5 5 4 Leucine rich repeat LRR_6 PF13516.6 OQR93312.1 - 4.1e-09 35.8 13.6 1.3 9.3 0.1 7.8 7 0 0 7 7 7 4 Leucine Rich repeat LRR_9 PF14580.6 OQR93312.1 - 6.6e-08 32.2 3.6 0.00023 20.7 0.7 2.8 1 1 1 2 2 2 2 Leucine-rich repeat LRR_1 PF00560.33 OQR93312.1 - 9.1e-05 22.5 17.2 7.7 7.5 0.2 7.1 7 1 0 7 7 7 3 Leucine Rich Repeat CoA_transf_3 PF02515.17 OQR93313.1 - 3.8e-107 358.6 0.0 6e-107 358.0 0.0 1.3 1 0 0 1 1 1 1 CoA-transferase family III His_Phos_2 PF00328.22 OQR93313.1 - 2.3e-31 109.5 0.4 4e-31 108.7 0.4 1.4 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Flp_N PF03930.14 OQR93313.1 - 0.12 12.3 0.2 0.36 10.8 0.0 1.8 2 0 0 2 2 2 0 Recombinase Flp protein N-terminus Pkinase_Tyr PF07714.17 OQR93324.1 - 2.1e-42 145.2 3.9 5.5e-22 78.3 0.0 4.6 2 2 2 4 4 4 4 Protein tyrosine kinase Pkinase PF00069.25 OQR93324.1 - 2.8e-33 115.4 0.4 1.3e-18 67.3 0.0 4.3 3 2 2 5 5 5 3 Protein kinase domain LRR_4 PF12799.7 OQR93324.1 - 1.5e-28 98.3 67.8 1.2e-06 28.7 2.5 10.5 8 2 1 10 10 10 7 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 OQR93324.1 - 3.2e-22 78.0 60.7 1.8e-08 34.0 5.5 8.2 6 2 2 8 8 8 6 Leucine rich repeat LRR_6 PF13516.6 OQR93324.1 - 1.7e-16 58.8 32.3 1 9.6 0.1 13.4 13 0 0 13 13 13 7 Leucine Rich repeat LRR_1 PF00560.33 OQR93324.1 - 2.1e-08 33.6 38.6 0.61 10.8 0.1 11.8 12 0 0 12 12 11 5 Leucine Rich Repeat FNIP PF05725.12 OQR93324.1 - 4.9e-08 33.0 0.0 0.96 9.7 0.0 4.4 3 1 0 3 3 3 2 FNIP Repeat LRR_9 PF14580.6 OQR93324.1 - 5.8e-05 22.7 26.7 0.073 12.6 1.4 4.3 3 1 0 3 3 3 3 Leucine-rich repeat Kinase-like PF14531.6 OQR93324.1 - 0.027 13.8 0.0 4.8 6.4 0.0 2.5 2 0 0 2 2 2 0 Kinase-like EpCAM_N PF18635.1 OQR93324.1 - 0.81 9.9 2.9 33 4.8 0.1 3.4 2 0 0 2 2 2 0 Epithelial cell adhesion molecule N-terminal domain V-set_CD47 PF08204.11 OQR93324.1 - 6.8 6.7 9.4 2.2 8.3 1.0 3.5 3 0 0 3 3 3 0 CD47 immunoglobulin-like domain Ricin_B_lectin PF00652.22 OQR93335.1 - 4.5e-63 211.2 42.2 9.7e-11 42.0 2.9 9.5 8 2 0 8 8 8 7 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.6 OQR93335.1 - 2.2e-19 69.9 19.4 0.0027 18.4 0.4 10.5 7 6 3 10 10 10 8 Ricin-type beta-trefoil lectin domain-like Glt_symporter PF03616.14 OQR93335.1 - 0.013 14.2 0.0 0.37 9.4 0.0 2.4 2 0 0 2 2 2 0 Sodium/glutamate symporter DUF4290 PF14123.6 OQR93335.1 - 0.09 12.3 0.0 0.21 11.1 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4290) dCMP_cyt_deam_1 PF00383.23 OQR93335.1 - 0.13 12.2 0.2 30 4.6 0.0 3.0 2 0 0 2 2 2 0 Cytidine and deoxycytidylate deaminase zinc-binding region Cadherin PF00028.17 OQR93335.1 - 0.31 11.5 3.6 82 3.7 0.0 4.7 5 0 0 5 5 5 0 Cadherin domain PRANC PF09372.10 OQR93335.1 - 6.1 7.2 9.9 1.6 9.1 1.8 4.2 7 0 0 7 7 7 0 PRANC domain Pkinase PF00069.25 OQR93336.1 - 5.6e-48 163.6 0.0 1.1e-47 162.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQR93336.1 - 2.1e-47 161.6 0.0 3.1e-47 161.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase TMEM72 PF16054.5 OQR93336.1 - 0.03 14.0 0.0 0.059 13.1 0.0 1.4 1 0 0 1 1 1 0 Transmembrane protein family 72 LapA_dom PF06305.11 OQR93336.1 - 0.071 12.9 0.1 0.69 9.8 0.0 2.2 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain PRA1 PF03208.19 OQR93336.1 - 0.13 11.9 0.0 0.23 11.1 0.0 1.3 1 0 0 1 1 1 0 PRA1 family protein Nup160 PF11715.8 OQR93356.1 - 2.5e-12 46.2 0.2 6e-11 41.7 0.2 2.0 1 1 0 1 1 1 1 Nucleoporin Nup120/160 Peptidase_C1 PF00112.23 OQR93357.1 - 7.4e-10 39.3 0.1 0.011 15.8 0.0 3.5 3 0 0 3 3 3 3 Papain family cysteine protease DUF2681 PF10883.8 OQR93357.1 - 0.16 12.4 0.4 0.35 11.3 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2681) Peptidase_M3 PF01432.20 OQR93358.1 - 1.2e-125 420.4 0.0 1.5e-125 420.1 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M3 DUF659 PF04937.15 OQR93359.1 - 2.9e-27 95.4 1.0 3.7e-27 95.0 1.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) IRF-2BP1_2 PF11261.8 OQR93359.1 - 0.027 14.0 0.0 0.13 11.9 0.0 2.0 2 0 0 2 2 2 0 Interferon regulatory factor 2-binding protein zinc finger MCM_bind PF09739.9 OQR93376.1 - 2.2e-62 211.3 0.6 6.6e-50 170.2 0.1 2.0 1 1 1 2 2 2 2 Mini-chromosome maintenance replisome factor MCM_lid PF17855.1 OQR93376.1 - 0.0004 20.7 0.0 0.00071 20.0 0.0 1.3 1 0 0 1 1 1 1 MCM AAA-lid domain HWE_HK PF07536.14 OQR93376.1 - 0.0089 16.7 0.1 0.031 15.0 0.1 1.9 2 0 0 2 2 2 1 HWE histidine kinase AAA_lid_2 PF17863.1 OQR93376.1 - 0.025 14.4 0.0 0.044 13.6 0.0 1.4 1 0 0 1 1 1 0 AAA lid domain AAA_lid_3 PF17862.1 OQR93376.1 - 0.17 11.7 0.0 0.39 10.6 0.0 1.7 1 0 0 1 1 1 0 AAA+ lid domain Robl_LC7 PF03259.17 OQR93377.1 - 9.6e-19 67.0 0.1 3.6e-18 65.1 0.0 2.0 2 0 0 2 2 2 1 Roadblock/LC7 domain Arm PF00514.23 OQR93377.1 - 5.2e-09 35.9 4.5 1.4 9.1 0.1 5.5 5 0 0 5 5 5 3 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 OQR93377.1 - 8.9e-05 22.8 1.7 0.017 15.5 0.1 3.1 2 1 0 2 2 2 1 HEAT repeats Arm_2 PF04826.13 OQR93377.1 - 0.0024 17.4 2.1 0.0036 16.8 0.6 1.9 1 1 0 2 2 2 1 Armadillo-like Cnd1 PF12717.7 OQR93377.1 - 0.01 15.9 2.8 3.4 7.7 0.1 3.0 2 1 1 3 3 3 0 non-SMC mitotic condensation complex subunit 1 LAMTOR5 PF16672.5 OQR93377.1 - 0.011 15.6 0.0 0.026 14.4 0.0 1.7 1 0 0 1 1 1 0 Ragulator complex protein LAMTOR5 V-ATPase_H_N PF03224.14 OQR93377.1 - 0.049 12.9 0.8 1.4 8.2 0.2 2.2 1 1 1 2 2 2 0 V-ATPase subunit H UNC45-central PF11701.8 OQR93377.1 - 0.082 12.9 1.7 11 6.0 0.1 2.7 1 1 1 2 2 2 0 Myosin-binding striated muscle assembly central HEAT_EZ PF13513.6 OQR93377.1 - 0.17 12.5 3.9 78 3.9 0.2 4.2 3 1 1 4 4 4 0 HEAT-like repeat HEAT PF02985.22 OQR93377.1 - 0.68 10.4 6.8 4 8.0 0.0 4.7 5 0 0 5 5 5 0 HEAT repeat DnaJ PF00226.31 OQR93378.1 - 1.2e-20 73.4 0.3 1.8e-20 72.8 0.3 1.3 1 0 0 1 1 1 1 DnaJ domain adh_short PF00106.25 OQR93379.1 - 2.8e-24 85.7 1.0 3e-17 62.7 0.1 2.9 2 1 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 OQR93379.1 - 9.3e-10 38.5 0.7 1e-07 31.8 0.0 2.5 2 1 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase PP2C PF00481.21 OQR93380.1 - 1.9e-43 149.0 0.0 2.8e-43 148.4 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C UQ_con PF00179.26 OQR93380.1 - 5.3e-06 26.1 0.2 9.4e-06 25.3 0.2 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme PP2C_2 PF13672.6 OQR93380.1 - 0.001 18.7 0.0 0.0018 18.0 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C Agarase_CBM PF17992.1 OQR93381.1 - 0.0048 16.5 0.1 0.026 14.1 0.0 2.2 2 0 0 2 2 2 1 Agarase CBM like domain zf-RING_5 PF14634.6 OQR93381.1 - 0.0049 16.8 6.1 0.01 15.8 6.1 1.6 1 0 0 1 1 1 1 zinc-RING finger domain ANAPC4_WD40 PF12894.7 OQR93381.1 - 0.0059 16.9 0.0 1.1 9.6 0.0 3.0 1 1 2 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain Mei4 PF13971.6 OQR93381.1 - 0.011 15.3 1.2 0.022 14.3 1.2 1.4 1 0 0 1 1 1 0 Meiosis-specific protein Mei4 RsgI_N PF12791.7 OQR93381.1 - 0.05 13.5 0.0 0.096 12.6 0.0 1.4 1 0 0 1 1 1 0 Anti-sigma factor N-terminus zf-RING_11 PF17123.5 OQR93381.1 - 1.3 8.9 6.5 0.096 12.4 0.7 2.2 2 0 0 2 2 2 0 RING-like zinc finger zf-RING_2 PF13639.6 OQR93381.1 - 2.6 8.5 7.8 8.4 6.8 7.8 1.9 1 0 0 1 1 1 0 Ring finger domain DUF1336 PF07059.12 OQR93401.1 - 1.1e-37 130.3 0.0 1.4e-37 130.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1336) FAD-oxidase_C PF02913.19 OQR93402.1 - 3.8e-41 141.4 0.0 6.8e-41 140.5 0.0 1.3 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain Abhydrolase_1 PF00561.20 OQR93402.1 - 1e-23 84.3 0.0 8.9e-23 81.2 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold FAD_binding_4 PF01565.23 OQR93402.1 - 2.9e-17 62.7 0.3 5.9e-17 61.7 0.3 1.5 1 0 0 1 1 1 1 FAD binding domain Abhydrolase_4 PF08386.10 OQR93402.1 - 8.1e-15 54.8 0.0 2.4e-14 53.3 0.0 1.8 1 0 0 1 1 1 1 TAP-like protein CENP-C_C PF11699.8 OQR93404.1 - 7.8e-06 26.0 0.0 0.00011 22.3 0.0 2.5 1 1 0 1 1 1 1 Mif2/CENP-C like Mif2_N PF15624.6 OQR93404.1 - 0.00021 22.0 6.7 0.00021 22.0 6.7 4.4 1 1 3 4 4 4 1 Kinetochore CENP-C fungal homologue, Mif2, N-terminal Cupin_2 PF07883.11 OQR93404.1 - 0.058 13.1 0.0 0.12 12.1 0.0 1.6 1 0 0 1 1 1 0 Cupin domain ABC_tran PF00005.27 OQR93405.1 - 1.5e-37 129.2 0.0 1.3e-17 64.6 0.0 2.3 2 0 0 2 2 2 2 ABC transporter RLI PF04068.15 OQR93405.1 - 5.5e-14 51.7 6.7 1.6e-13 50.2 6.7 1.8 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI SMC_N PF02463.19 OQR93405.1 - 1.8e-08 34.1 3.3 0.0042 16.5 0.1 3.8 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain Fer4 PF00037.27 OQR93405.1 - 2.8e-08 33.2 3.3 2.8e-08 33.2 3.3 2.8 3 0 0 3 3 2 1 4Fe-4S binding domain AAA_21 PF13304.6 OQR93405.1 - 3.2e-08 33.7 4.4 0.39 10.5 1.5 4.2 2 2 1 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 OQR93405.1 - 3.3e-07 30.9 0.0 0.0018 18.7 0.0 2.4 2 0 0 2 2 2 2 AAA ATPase domain AAA PF00004.29 OQR93405.1 - 4.2e-06 27.2 0.0 0.031 14.7 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_15 PF13175.6 OQR93405.1 - 1.5e-05 24.9 0.0 0.28 10.8 0.0 3.1 3 0 0 3 3 3 2 AAA ATPase domain Fer4_6 PF12837.7 OQR93405.1 - 1.5e-05 24.9 2.4 1.5e-05 24.9 2.4 2.8 3 0 0 3 3 2 1 4Fe-4S binding domain AAA_22 PF13401.6 OQR93405.1 - 4.7e-05 23.7 0.0 0.022 15.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 OQR93405.1 - 0.0001 22.5 0.0 0.069 13.3 0.0 2.5 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 OQR93405.1 - 0.00012 22.1 0.1 0.33 10.9 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_29 PF13555.6 OQR93405.1 - 0.00015 21.5 0.2 0.33 10.7 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain TsaE PF02367.17 OQR93405.1 - 0.00016 21.6 0.1 0.026 14.5 0.1 2.5 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE NACHT PF05729.12 OQR93405.1 - 0.00019 21.4 1.3 0.044 13.7 0.0 2.5 2 0 0 2 2 2 1 NACHT domain RNA_helicase PF00910.22 OQR93405.1 - 0.00024 21.5 0.1 0.57 10.6 0.0 3.0 2 1 0 2 2 2 1 RNA helicase AAA_7 PF12775.7 OQR93405.1 - 0.00025 20.6 0.2 0.17 11.4 0.1 3.3 2 1 1 3 3 3 1 P-loop containing dynein motor region SRP54 PF00448.22 OQR93405.1 - 0.00028 20.6 0.7 0.11 12.1 0.0 2.3 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_24 PF13479.6 OQR93405.1 - 0.0011 18.7 0.1 0.25 11.1 0.0 2.4 2 0 0 2 2 2 1 AAA domain Fer4_2 PF12797.7 OQR93405.1 - 0.0013 18.7 0.8 0.0013 18.7 0.8 2.8 2 0 0 2 2 2 1 4Fe-4S binding domain Fer4_10 PF13237.6 OQR93405.1 - 0.0014 18.7 1.3 0.0014 18.7 1.3 2.5 1 1 1 2 2 2 2 4Fe-4S dicluster domain AAA_18 PF13238.6 OQR93405.1 - 0.0017 18.9 0.0 1.3 9.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain Fer4_7 PF12838.7 OQR93405.1 - 0.0021 18.6 1.2 0.0021 18.6 1.2 2.6 1 1 2 3 3 3 2 4Fe-4S dicluster domain Rad17 PF03215.15 OQR93405.1 - 0.0022 17.9 0.0 0.13 12.2 0.0 2.4 2 0 0 2 2 2 1 Rad17 P-loop domain Fer4_21 PF14697.6 OQR93405.1 - 0.0024 17.9 12.7 0.0071 16.4 12.7 1.8 1 0 0 1 1 1 1 4Fe-4S dicluster domain AAA_28 PF13521.6 OQR93405.1 - 0.0031 17.8 0.0 0.81 9.9 0.0 2.4 2 0 0 2 2 2 1 AAA domain Fer4_9 PF13187.6 OQR93405.1 - 0.004 17.3 13.0 0.011 15.9 13.0 1.8 1 0 0 1 1 1 1 4Fe-4S dicluster domain AAA_5 PF07728.14 OQR93405.1 - 0.0076 16.3 2.0 0.34 10.9 0.0 3.4 3 1 0 3 3 3 1 AAA domain (dynein-related subfamily) Fer4_16 PF13484.6 OQR93405.1 - 0.0085 17.0 0.2 0.0085 17.0 0.2 2.7 2 0 0 2 2 2 1 4Fe-4S double cluster binding domain VirE PF05272.11 OQR93405.1 - 0.0096 15.7 0.0 3.1 7.5 0.0 2.3 2 0 0 2 2 2 1 Virulence-associated protein E AAA_30 PF13604.6 OQR93405.1 - 0.016 15.0 0.2 1.6 8.4 0.0 2.4 2 0 0 2 2 2 0 AAA domain dNK PF01712.19 OQR93405.1 - 0.024 14.5 0.1 0.76 9.6 0.0 2.5 3 0 0 3 3 2 0 Deoxynucleoside kinase NTPase_1 PF03266.15 OQR93405.1 - 0.028 14.3 1.0 1.8 8.5 0.0 2.8 2 0 0 2 2 2 0 NTPase Thymidylate_kin PF02223.17 OQR93405.1 - 0.028 14.1 0.1 9.7 5.8 0.0 2.5 2 0 0 2 2 2 0 Thymidylate kinase AAA_14 PF13173.6 OQR93405.1 - 0.037 14.1 0.5 9.3 6.3 0.0 3.1 2 1 1 3 3 3 0 AAA domain MMR_HSR1 PF01926.23 OQR93405.1 - 0.044 13.9 1.0 4.2 7.5 0.0 2.7 2 1 0 2 2 2 0 50S ribosome-binding GTPase NB-ARC PF00931.22 OQR93405.1 - 0.046 12.9 0.1 1.6 7.8 0.0 2.2 2 0 0 2 2 2 0 NB-ARC domain Septin PF00735.18 OQR93405.1 - 0.05 12.9 0.0 0.88 8.8 0.0 2.2 2 0 0 2 2 2 0 Septin MobB PF03205.14 OQR93405.1 - 0.056 13.3 1.0 0.67 9.9 0.0 2.4 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B MeaB PF03308.16 OQR93405.1 - 0.13 11.2 0.3 1.6 7.6 0.1 2.2 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_19 PF13245.6 OQR93405.1 - 0.16 12.3 0.1 1.5 9.2 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.6 OQR93405.1 - 0.33 11.4 9.2 0.18 12.3 0.5 2.7 2 1 0 3 3 2 0 AAA domain AAA_13 PF13166.6 OQR93405.1 - 0.46 9.1 1.5 0.46 9.1 0.0 1.7 2 0 0 2 2 1 0 AAA domain Fer4_17 PF13534.6 OQR93405.1 - 4.2 8.0 12.2 0.072 13.7 1.2 2.5 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_8 PF13183.6 OQR93405.1 - 5.3 7.6 11.8 0.4 11.2 1.7 2.5 1 1 1 2 2 2 0 4Fe-4S dicluster domain Orthoreo_P10 PF07204.11 OQR93406.1 - 0.0019 18.2 0.3 0.0019 18.2 0.3 2.2 1 1 1 2 2 2 1 Orthoreovirus membrane fusion protein p10 Shisa PF13908.6 OQR93406.1 - 0.021 15.1 0.4 0.021 15.1 0.4 1.5 1 1 0 1 1 1 0 Wnt and FGF inhibitory regulator Pkr1 PF08636.10 OQR93406.1 - 0.036 14.2 4.5 0.036 14.2 4.5 2.9 3 0 0 3 3 3 0 ER protein Pkr1 Myelin_PLP PF01275.19 OQR93406.1 - 0.047 13.6 10.2 0.06 13.2 10.2 1.3 1 0 0 1 1 1 0 Myelin proteolipid protein (PLP or lipophilin) Glycophorin_A PF01102.18 OQR93406.1 - 0.16 12.3 0.4 0.16 12.3 0.4 2.1 1 1 1 2 2 2 0 Glycophorin A Spo7 PF03907.13 OQR93406.1 - 0.31 10.5 7.6 2 7.8 1.3 2.2 2 0 0 2 2 2 0 Spo7-like protein DUF4271 PF14093.6 OQR93406.1 - 0.46 10.4 22.8 0.026 14.5 17.2 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4271) WBP-1 PF11669.8 OQR93406.1 - 6.3 7.5 8.7 0.54 10.9 2.4 2.3 1 1 1 2 2 2 0 WW domain-binding protein 1 Ank_4 PF13637.6 OQR93449.1 - 2.8e-20 72.4 8.1 3.5e-05 24.3 0.2 5.3 3 1 3 6 6 6 5 Ankyrin repeats (many copies) Ank_2 PF12796.7 OQR93449.1 - 3.6e-20 72.3 13.1 7.5e-09 36.1 0.8 4.0 1 1 2 5 5 5 4 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OQR93449.1 - 4.7e-12 45.9 11.6 0.37 11.2 0.0 6.5 2 2 4 6 6 6 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQR93449.1 - 3.3e-09 36.2 4.0 13 6.8 0.0 7.2 7 0 0 7 7 7 1 Ankyrin repeat DUF5049 PF16468.5 OQR93449.1 - 6.7e-05 22.7 4.1 16 5.5 0.0 5.3 2 2 3 5 5 5 3 Domain of unknown function (DUF5049) DUF249 PF03158.13 OQR93449.1 - 0.012 15.4 0.4 5.2 6.7 0.0 3.2 3 0 0 3 3 3 0 Multigene family 530 protein DUF3447 PF11929.8 OQR93449.1 - 0.07 13.1 1.7 8.1 6.5 0.2 3.3 1 1 2 3 3 3 0 Domain of unknown function (DUF3447) Ank PF00023.30 OQR93449.1 - 0.16 12.5 5.9 38 4.9 0.2 5.5 3 1 2 5 5 5 0 Ankyrin repeat DUF3523 PF12037.8 OQR93450.1 - 1.1e-61 208.5 14.5 1.7e-61 207.9 14.5 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3523) AAA PF00004.29 OQR93450.1 - 2.3e-22 79.8 0.0 4.8e-22 78.8 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 OQR93450.1 - 2.8e-05 24.6 9.2 0.00013 22.4 0.3 3.8 3 1 0 3 3 3 1 AAA ATPase domain RuvB_N PF05496.12 OQR93450.1 - 0.00011 21.9 0.0 0.00033 20.5 0.0 1.8 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 OQR93450.1 - 0.00015 22.0 6.0 0.012 15.9 0.0 3.6 2 1 2 4 4 4 2 AAA domain AAA_33 PF13671.6 OQR93450.1 - 0.0006 20.0 0.7 0.0016 18.6 0.0 2.1 2 1 0 2 2 2 1 AAA domain AAA_5 PF07728.14 OQR93450.1 - 0.00085 19.3 0.2 0.0098 15.9 0.1 2.5 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 OQR93450.1 - 0.0034 16.8 0.1 0.012 15.1 0.1 1.9 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 OQR93450.1 - 0.0036 17.2 0.0 0.008 16.0 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 OQR93450.1 - 0.0065 17.0 1.8 0.015 15.9 0.1 2.8 2 1 0 2 2 2 1 AAA domain AAA_lid_3 PF17862.1 OQR93450.1 - 0.0071 16.1 0.0 0.016 15.0 0.0 1.6 1 0 0 1 1 1 1 AAA+ lid domain Zot PF05707.12 OQR93450.1 - 0.008 15.8 0.0 0.12 12.0 0.0 2.3 2 0 0 2 2 2 1 Zonular occludens toxin (Zot) TsaE PF02367.17 OQR93450.1 - 0.012 15.6 0.0 0.034 14.1 0.0 1.7 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE IstB_IS21 PF01695.17 OQR93450.1 - 0.016 15.0 0.0 0.062 13.0 0.0 2.0 2 0 0 2 2 2 0 IstB-like ATP binding protein RNA_helicase PF00910.22 OQR93450.1 - 0.029 14.8 0.1 0.11 12.9 0.0 2.0 2 0 0 2 2 1 0 RNA helicase Sigma54_activ_2 PF14532.6 OQR93450.1 - 0.054 13.6 0.0 0.23 11.6 0.0 2.1 2 0 0 2 2 2 0 Sigma-54 interaction domain Rad17 PF03215.15 OQR93450.1 - 0.073 13.0 0.0 0.2 11.6 0.0 1.9 1 1 0 1 1 1 0 Rad17 P-loop domain AAA_25 PF13481.6 OQR93450.1 - 0.084 12.4 0.2 0.26 10.8 0.2 1.8 1 1 0 1 1 1 0 AAA domain NACHT PF05729.12 OQR93450.1 - 0.1 12.5 0.1 0.41 10.5 0.0 2.0 2 0 0 2 2 2 0 NACHT domain AAA_28 PF13521.6 OQR93450.1 - 0.13 12.5 0.0 0.13 12.5 0.0 2.9 3 1 0 3 3 2 0 AAA domain AAA_11 PF13086.6 OQR93450.1 - 0.13 12.0 0.0 0.13 12.0 0.0 2.8 3 0 0 3 3 1 0 AAA domain AAA_17 PF13207.6 OQR93450.1 - 0.83 10.1 4.6 0.83 10.1 0.1 2.7 2 0 0 2 2 2 0 AAA domain Hydin_ADK PF17213.3 OQR93450.1 - 3.1 8.0 7.0 1.6 9.0 0.1 2.4 2 0 0 2 2 2 0 Hydin Adenylate kinase-like domain DUF3611 PF12263.8 OQR93451.1 - 0.13 12.2 3.9 0.18 11.7 3.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3611) Pkinase PF00069.25 OQR93460.1 - 5.2e-36 124.4 0.0 1.3e-35 123.1 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQR93460.1 - 1.9e-16 60.1 0.0 2.7e-16 59.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 OQR93460.1 - 0.0014 18.0 0.1 0.0029 17.0 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OQR93460.1 - 0.0031 17.5 0.1 0.0069 16.3 0.1 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 OQR93460.1 - 0.011 15.0 0.0 0.17 11.2 0.0 2.1 1 1 1 2 2 2 0 Kinase-like VEGF_C PF14554.6 OQR93460.1 - 0.063 13.4 0.0 0.12 12.5 0.0 1.4 1 0 0 1 1 1 0 VEGF heparin-binding domain FYVE PF01363.21 OQR93461.1 - 1.5e-09 37.9 17.6 3.6e-09 36.6 17.6 1.6 1 0 0 1 1 1 1 FYVE zinc finger GAF PF01590.26 OQR93461.1 - 1.1e-06 29.3 0.3 4.4e-06 27.4 0.1 2.1 2 0 0 2 2 2 1 GAF domain FYVE_2 PF02318.16 OQR93461.1 - 0.0026 18.0 7.3 0.0063 16.7 7.3 1.6 1 0 0 1 1 1 1 FYVE-type zinc finger Cupin_8 PF13621.6 OQR93462.1 - 1.7e-77 260.6 2.4 2.3e-77 260.1 2.4 1.1 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.12 OQR93462.1 - 0.001 18.6 0.1 0.0025 17.3 0.1 1.6 1 0 0 1 1 1 1 Cupin superfamily protein DUF2661 PF10860.8 OQR93462.1 - 0.012 15.7 0.8 0.036 14.2 0.8 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2661) JmjC PF02373.22 OQR93462.1 - 0.017 15.6 0.0 0.1 13.1 0.0 2.3 2 0 0 2 2 2 0 JmjC domain, hydroxylase ERCC3_RAD25_C PF16203.5 OQR93463.1 - 2.8e-108 360.8 0.2 5.1e-108 360.0 0.2 1.4 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase Helicase_C_3 PF13625.6 OQR93463.1 - 1.1e-34 119.3 0.0 2.3e-34 118.3 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 OQR93463.1 - 1.8e-14 54.1 0.0 4.6e-14 52.8 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 OQR93463.1 - 3.4e-11 43.5 0.2 1.5e-10 41.4 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain SNF2_N PF00176.23 OQR93463.1 - 2.2e-07 29.9 0.0 3.3e-07 29.3 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain VBS PF08913.10 OQR93463.1 - 0.075 13.5 0.2 0.23 11.9 0.2 1.8 1 0 0 1 1 1 0 Vinculin Binding Site RNR_N PF08343.10 OQR93463.1 - 0.53 10.3 3.4 1.3 9.1 0.6 3.0 3 0 0 3 3 3 0 Ribonucleotide reductase N-terminal FYVE PF01363.21 OQR93464.1 - 3.3e-13 49.6 10.7 7.2e-13 48.5 10.7 1.5 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.16 OQR93464.1 - 0.0051 17.0 5.0 0.012 15.8 5.0 1.5 1 0 0 1 1 1 1 FYVE-type zinc finger zf-RING_2 PF13639.6 OQR93464.1 - 0.076 13.4 10.0 0.18 12.2 10.0 1.7 1 0 0 1 1 1 0 Ring finger domain Zf_RING PF16744.5 OQR93464.1 - 0.63 10.2 5.3 1.3 9.1 5.3 1.5 1 0 0 1 1 1 0 KIAA1045 RING finger DUF2431 PF10354.9 OQR93465.1 - 1.8e-05 25.1 0.0 0.00023 21.5 0.0 2.6 1 1 0 1 1 1 1 Domain of unknown function (DUF2431) Pep_deformylase PF01327.21 OQR93466.1 - 2.3e-44 150.8 0.0 2.7e-44 150.6 0.0 1.0 1 0 0 1 1 1 1 Polypeptide deformylase SHR-BD PF06650.12 OQR93477.1 - 2.3e-19 69.8 1.0 1.9e-16 60.3 0.0 3.8 2 2 1 3 3 3 1 SHR-binding domain of vacuolar-sorting associated protein 13 EF-hand_7 PF13499.6 OQR93477.1 - 1.2e-17 64.1 10.1 5.9e-09 36.3 0.2 2.9 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 OQR93477.1 - 3.2e-15 54.5 10.4 8.3e-05 21.9 0.0 4.8 4 0 0 4 4 4 3 EF hand VPS13_C PF16909.5 OQR93477.1 - 9.7e-15 54.8 2.3 9.9e-09 35.2 0.0 2.8 2 0 0 2 2 2 2 Vacuolar-sorting-associated 13 protein C-terminal EF-hand_6 PF13405.6 OQR93477.1 - 1.3e-14 52.8 7.0 3.9e-05 23.2 0.0 4.7 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 OQR93477.1 - 2.2e-08 33.8 10.3 0.01 15.7 0.1 4.7 3 1 1 4 4 4 3 EF-hand domain pair EF-hand_5 PF13202.6 OQR93477.1 - 2.6e-08 33.0 11.4 0.008 15.6 0.0 4.6 4 0 0 4 4 4 3 EF hand ATG_C PF09333.11 OQR93477.1 - 3.1e-07 30.6 0.0 1.2e-06 28.8 0.0 2.0 1 0 0 1 1 1 1 Autophagy-related protein C terminal domain C2 PF00168.30 OQR93477.1 - 3.8e-06 27.1 0.1 1.2e-05 25.5 0.1 1.9 1 0 0 1 1 1 1 C2 domain SPARC_Ca_bdg PF10591.9 OQR93477.1 - 0.058 13.7 8.5 1.7 9.0 0.6 3.4 3 1 0 3 3 3 0 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_10 PF14788.6 OQR93477.1 - 0.089 12.7 0.7 0.91 9.4 0.0 2.8 3 0 0 3 3 3 0 EF hand Alpha-amylase PF00128.24 OQR93478.1 - 4e-73 246.9 0.3 4.2e-56 190.9 1.0 3.0 2 1 0 2 2 2 2 Alpha amylase, catalytic domain V-set_2 PF15910.5 OQR93478.1 - 0.016 15.3 0.1 0.83 9.8 0.0 2.6 2 0 0 2 2 2 0 ICOS V-set domain PH_11 PF15413.6 OQR93478.1 - 0.11 13.0 0.0 0.28 11.6 0.0 1.7 1 0 0 1 1 1 0 Pleckstrin homology domain Aminotran_5 PF00266.19 OQR93478.1 - 0.14 11.1 0.1 0.24 10.3 0.1 1.3 1 0 0 1 1 1 0 Aminotransferase class-V DEC-1_N PF04625.13 OQR93478.1 - 0.15 11.0 0.5 0.24 10.4 0.5 1.2 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region hDGE_amylase PF14701.6 OQR93478.1 - 0.37 9.8 3.5 7.9 5.4 0.1 2.7 4 0 0 4 4 4 0 Glycogen debranching enzyme, glucanotransferase domain COX7C PF02935.16 OQR93482.1 - 7.4 6.9 7.1 1 9.7 1.4 2.4 2 2 0 2 2 2 0 Cytochrome c oxidase subunit VIIc DUF5472 PF17566.2 OQR93483.1 - 0.75 9.8 0.1 0.75 9.8 0.1 2.5 2 1 0 2 2 2 0 Family of unknown function (DUF5472) Ank_4 PF13637.6 OQR93501.1 - 3.9e-10 40.1 0.8 3.4e-07 30.7 0.1 2.3 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 OQR93501.1 - 1.1e-08 35.1 0.5 0.0057 16.9 0.0 3.0 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 OQR93501.1 - 2.6e-07 31.1 0.0 3.5e-07 30.7 0.0 1.2 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OQR93501.1 - 0.00026 21.2 0.3 4.3 8.2 0.0 3.3 3 0 0 3 3 3 2 Ankyrin repeat UQ_con PF00179.26 OQR93502.1 - 9.9e-48 161.4 0.0 1.1e-47 161.2 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme NVEALA PF14055.6 OQR93509.1 - 0.045 13.7 0.6 0.32 11.0 0.1 2.1 2 0 0 2 2 2 0 NVEALA protein Gram_pos_anchor PF00746.21 OQR93509.1 - 0.49 10.4 2.0 5.4 7.0 0.0 2.4 3 0 0 3 3 3 0 LPXTG cell wall anchor motif CH PF00307.31 OQR93510.1 - 7e-20 71.2 1.2 4.5e-08 33.3 0.0 4.2 3 1 0 3 3 3 2 Calponin homology (CH) domain ASH PF15780.5 OQR93510.1 - 1.5e-12 47.5 0.0 3.2e-12 46.5 0.0 1.6 1 0 0 1 1 1 1 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin CAMSAP_CH PF11971.8 OQR93510.1 - 4.7e-09 35.9 0.2 0.00075 19.3 0.0 3.0 2 0 0 2 2 2 2 CAMSAP CH domain IQ PF00612.27 OQR93510.1 - 2.6e-05 23.6 0.4 2.6e-05 23.6 0.4 18.8 20 0 0 20 20 20 7 IQ calmodulin-binding motif TMEM131_like PF12371.8 OQR93510.1 - 0.13 12.5 0.1 0.46 10.8 0.1 1.9 1 0 0 1 1 1 0 Transmembrane protein 131-like Ribonuc_L-PSP PF01042.21 OQR93511.1 - 2.8e-27 95.1 0.0 3.2e-27 95.0 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP HSF_DNA-bind PF00447.17 OQR93512.1 - 1.3e-22 80.2 0.4 1.8e-22 79.7 0.4 1.2 1 0 0 1 1 1 1 HSF-type DNA-binding Ank_2 PF12796.7 OQR93513.1 - 7.2e-37 125.8 18.1 8.6e-12 45.5 0.2 4.1 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQR93513.1 - 2.9e-25 88.3 7.6 5.5e-06 26.8 0.0 6.6 2 2 5 7 7 7 7 Ankyrin repeats (many copies) Ank_5 PF13857.6 OQR93513.1 - 3.2e-20 71.9 8.4 0.0061 16.9 0.1 7.9 1 1 8 9 9 9 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQR93513.1 - 6.4e-19 66.1 1.5 0.5 11.1 0.0 8.9 5 4 4 9 9 9 3 Ankyrin repeat DUF5049 PF16468.5 OQR93513.1 - 6e-07 29.3 0.4 1.7 8.6 0.0 5.9 6 1 2 8 8 8 2 Domain of unknown function (DUF5049) DUF249 PF03158.13 OQR93513.1 - 0.0002 21.2 2.1 0.23 11.2 0.0 3.6 2 1 2 4 4 4 1 Multigene family 530 protein DUF4751 PF15942.5 OQR93513.1 - 0.0029 17.6 2.3 0.55 10.2 0.0 3.2 2 2 2 4 4 4 2 Domain of unknown function (DUF4751) Ank PF00023.30 OQR93513.1 - 0.008 16.6 1.5 19 5.9 0.0 5.6 2 2 2 4 4 4 0 Ankyrin repeat DUF5644 PF18712.1 OQR93513.1 - 0.053 13.5 0.1 3.4 7.7 0.0 3.2 2 1 1 3 3 3 0 Family of unknown function (DUF5644) DUF1843 PF08898.10 OQR93513.1 - 0.056 14.0 0.2 9.8 6.8 0.0 3.6 5 0 0 5 5 4 0 Domain of unknown function (DUF1843) TBPIP PF07106.13 OQR93513.1 - 0.075 13.0 0.0 17 5.4 0.0 3.6 3 1 0 3 3 3 0 TBPIP/Hop2 winged helix domain LSM PF01423.22 OQR93514.1 - 7e-22 76.9 0.3 8.5e-22 76.6 0.3 1.0 1 0 0 1 1 1 1 LSM domain HECT PF00632.25 OQR93549.1 - 1.6e-91 307.0 0.0 2.6e-91 306.3 0.0 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Pkinase PF00069.25 OQR93550.1 - 3.3e-66 223.3 0.0 4.2e-66 223.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQR93550.1 - 6.1e-30 104.4 0.0 9.8e-30 103.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OQR93550.1 - 8.1e-05 22.1 0.0 0.00015 21.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 OQR93550.1 - 0.0022 17.9 0.0 0.0043 17.0 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 OQR93550.1 - 0.0036 16.7 0.0 0.0057 16.0 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 OQR93550.1 - 0.15 10.8 0.0 0.26 10.0 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase FTA2 PF13095.6 OQR93550.1 - 0.15 11.7 0.0 0.22 11.1 0.0 1.3 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 CD36 PF01130.21 OQR93551.1 - 2.4e-35 122.0 9.5 1.7e-23 82.9 1.4 3.3 2 1 1 3 3 3 3 CD36 family DUF2200 PF09966.9 OQR93551.1 - 1.1 9.4 5.5 21 5.3 0.0 4.1 5 0 0 5 5 5 0 Uncharacterized protein conserved in bacteria (DUF2200) CCDC50_N PF15295.6 OQR93552.1 - 0.085 13.0 4.7 0.32 11.2 4.7 1.9 1 1 0 1 1 1 0 Coiled-coil domain-containing protein 50 N-terminus PTPlike_phytase PF14566.6 OQR93552.1 - 0.091 12.9 0.5 0.15 12.2 0.5 1.4 1 0 0 1 1 1 0 Inositol hexakisphosphate zf-RING_2 PF13639.6 OQR93553.1 - 6.1e-13 48.9 8.0 6.1e-13 48.9 8.0 2.3 2 0 0 2 2 2 1 Ring finger domain zf-RING_11 PF17123.5 OQR93553.1 - 6.4e-09 35.4 5.7 1.4e-08 34.3 5.7 1.6 1 0 0 1 1 1 1 RING-like zinc finger zf-rbx1 PF12678.7 OQR93553.1 - 8.2e-08 32.4 5.4 8.2e-08 32.4 5.4 2.2 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 OQR93553.1 - 4.9e-07 29.7 4.3 1.2e-06 28.4 4.3 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 OQR93553.1 - 5.7e-07 29.3 7.7 1.2e-06 28.2 7.7 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 OQR93553.1 - 9.8e-07 28.5 9.0 1.9e-06 27.6 9.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 OQR93553.1 - 2.7e-06 27.1 6.0 5.9e-06 26.1 6.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 OQR93553.1 - 7.5e-06 25.9 10.3 8.3e-06 25.8 6.2 2.6 2 1 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.6 OQR93553.1 - 0.0001 22.2 7.6 0.00019 21.3 7.6 1.5 1 0 0 1 1 1 1 zinc-RING finger domain Zn_ribbon_17 PF17120.5 OQR93553.1 - 0.00021 20.9 5.4 0.00021 20.9 5.4 2.3 2 0 0 2 2 2 1 Zinc-ribbon, C4HC2 type zf-Nse PF11789.8 OQR93553.1 - 0.00049 19.9 2.4 0.00095 18.9 2.4 1.4 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit FANCL_C PF11793.8 OQR93553.1 - 0.00089 19.4 10.5 0.0061 16.7 10.5 2.2 1 1 0 1 1 1 1 FANCL C-terminal domain RINGv PF12906.7 OQR93553.1 - 0.0012 18.9 9.3 0.0029 17.7 9.3 1.7 1 0 0 1 1 1 1 RING-variant domain zf-RING-like PF08746.11 OQR93553.1 - 0.0059 16.9 3.3 0.013 15.8 3.3 1.6 1 0 0 1 1 1 1 RING-like domain Prok-RING_4 PF14447.6 OQR93553.1 - 0.0068 16.3 6.2 0.012 15.4 6.2 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 PHD PF00628.29 OQR93553.1 - 0.078 12.9 7.9 0.16 11.9 7.9 1.6 1 0 0 1 1 1 0 PHD-finger Zf_RING PF16744.5 OQR93553.1 - 0.086 13.0 5.4 0.17 12.1 5.4 1.5 1 0 0 1 1 1 0 KIAA1045 RING finger RBFA PF02033.18 OQR93553.1 - 0.16 12.5 0.1 0.35 11.3 0.1 1.5 1 0 0 1 1 1 0 Ribosome-binding factor A zf-RING_4 PF14570.6 OQR93553.1 - 0.22 11.3 8.0 0.42 10.4 8.0 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain START PF01852.19 OQR93554.1 - 3.8e-23 82.0 0.0 4.1e-23 81.9 0.0 1.0 1 0 0 1 1 1 1 START domain Pkinase PF00069.25 OQR93555.1 - 3.4e-52 177.4 0.0 4.3e-52 177.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQR93555.1 - 5.1e-27 94.8 0.0 2e-26 92.8 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 OQR93555.1 - 0.00018 21.5 0.4 0.02 14.8 0.1 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family Haspin_kinase PF12330.8 OQR93555.1 - 0.00053 19.0 0.0 0.00088 18.3 0.0 1.3 1 0 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 OQR93555.1 - 0.00076 18.4 0.0 0.0012 17.7 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase RIO1 PF01163.22 OQR93555.1 - 0.013 15.1 0.0 0.028 14.0 0.0 1.5 1 0 0 1 1 1 0 RIO1 family Kinase-like PF14531.6 OQR93555.1 - 0.014 14.7 0.0 0.02 14.2 0.0 1.5 1 1 0 1 1 1 0 Kinase-like UPF0052 PF01933.18 OQR93556.1 - 1.9e-82 276.8 0.3 2.9e-82 276.2 0.3 1.2 1 0 0 1 1 1 1 Uncharacterised protein family UPF0052 UQ_con PF00179.26 OQR93556.1 - 8.6e-52 174.5 0.0 1.4e-51 173.8 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme HAD_2 PF13419.6 OQR93556.1 - 6.1e-10 39.5 0.0 1.6e-09 38.1 0.0 1.8 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 OQR93556.1 - 6.5e-05 23.3 0.0 0.00013 22.3 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 OQR93556.1 - 0.021 14.9 0.0 0.046 13.8 0.0 1.5 1 0 0 1 1 1 0 HAD-hyrolase-like HAD PF12710.7 OQR93556.1 - 0.096 13.1 0.0 0.22 11.9 0.0 1.6 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase RWD PF05773.22 OQR93556.1 - 0.14 12.5 0.0 0.32 11.3 0.0 1.6 1 0 0 1 1 1 0 RWD domain Atx10homo_assoc PF09759.9 OQR93557.1 - 0.00035 20.5 5.3 0.6 10.2 1.0 3.8 2 1 2 4 4 4 2 Spinocerebellar ataxia type 10 protein domain SAPS PF04499.15 OQR93557.1 - 0.006 15.4 1.1 0.009 14.8 0.3 1.7 2 0 0 2 2 2 1 SIT4 phosphatase-associated protein DUF3361 PF11841.8 OQR93557.1 - 0.016 15.2 9.6 5.5 6.9 0.5 3.9 3 1 1 4 4 4 0 Domain of unknown function (DUF3361) Mis14 PF08641.12 OQR93557.1 - 0.046 14.0 0.2 0.11 12.8 0.2 1.7 1 0 0 1 1 1 0 Kinetochore protein Mis14 like DUF4476 PF14771.6 OQR93557.1 - 0.82 10.0 3.2 7.6 6.9 0.1 3.2 2 1 1 3 3 3 0 Domain of unknown function (DUF4476) LRR_4 PF12799.7 OQR93560.1 - 3.9e-06 27.1 9.7 0.018 15.5 0.1 5.1 6 0 0 6 6 6 2 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 OQR93560.1 - 0.00011 22.0 11.0 0.038 14.0 0.1 6.2 7 0 0 7 7 7 2 Leucine Rich repeat LRR_8 PF13855.6 OQR93560.1 - 0.63 9.9 8.1 0.64 9.8 1.6 3.8 3 1 0 3 3 3 0 Leucine rich repeat TPH PF13868.6 OQR93561.1 - 5.7 5.3 148.1 0.77 8.2 67.8 2.8 2 1 1 3 3 3 0 Trichohyalin-plectin-homology domain SNF2_N PF00176.23 OQR93562.1 - 5.3e-57 193.1 0.4 1.8e-55 188.0 0.4 3.0 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 OQR93562.1 - 1.3e-16 61.0 0.0 1.9e-15 57.2 0.0 2.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain zf-PARP PF00645.18 OQR93562.1 - 1.2e-06 29.3 1.0 4.3e-05 24.3 0.2 3.3 2 0 0 2 2 2 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region zf-C3HC4_3 PF13920.6 OQR93562.1 - 1.2e-05 25.1 5.1 1.2e-05 25.1 5.1 3.5 4 0 0 4 4 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 OQR93562.1 - 2.3e-05 24.1 8.5 2.3e-05 24.1 8.5 2.6 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OQR93562.1 - 0.00038 20.3 7.3 0.00038 20.3 7.3 3.0 3 1 0 3 3 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 OQR93562.1 - 0.00088 19.6 7.2 0.00088 19.6 7.2 2.8 2 0 0 2 2 2 1 Ring finger domain zf-RING_UBOX PF13445.6 OQR93562.1 - 0.0014 18.6 2.1 0.0014 18.6 2.1 2.4 2 1 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 OQR93562.1 - 0.0061 16.4 7.8 0.0061 16.4 7.8 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 OQR93562.1 - 0.0076 16.5 3.9 0.0076 16.5 3.9 2.4 2 0 0 2 2 1 1 RING-H2 zinc finger domain LcrV PF04792.12 OQR93562.1 - 0.024 13.9 0.0 0.045 13.0 0.0 1.4 1 0 0 1 1 1 0 V antigen (LcrV) protein zf-ANAPC11 PF12861.7 OQR93562.1 - 2.4 8.2 7.8 0.074 13.1 0.9 2.0 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.6 OQR93562.1 - 3 8.1 12.0 1.8 8.8 9.1 2.3 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-ribbon_3 PF13248.6 OQR93562.1 - 4 7.0 6.0 3.1 7.3 0.0 3.4 3 0 0 3 3 2 0 zinc-ribbon domain Sld5 PF05916.11 OQR93597.1 - 1.2e-06 28.9 0.2 2.3e-06 28.0 0.2 1.4 1 0 0 1 1 1 1 GINS complex protein Rft-1 PF04506.13 OQR93598.1 - 3.1e-84 283.6 22.8 1.6e-50 172.3 4.5 2.2 1 1 1 2 2 2 2 Rft protein Kinesin PF00225.23 OQR93598.1 - 4.4e-20 71.9 0.7 2.3e-18 66.2 0.7 3.0 1 1 0 1 1 1 1 Kinesin motor domain Polysacc_synt_C PF14667.6 OQR93598.1 - 5.8e-05 23.2 14.0 5.8e-05 23.2 14.0 3.0 2 1 1 3 3 3 1 Polysaccharide biosynthesis C-terminal domain DivIC PF04977.15 OQR93598.1 - 0.0003 20.5 4.3 0.0003 20.5 4.3 3.0 1 1 1 2 2 2 1 Septum formation initiator bZIP_1 PF00170.21 OQR93598.1 - 0.0014 18.7 2.4 0.0014 18.7 2.4 2.6 2 0 0 2 2 2 1 bZIP transcription factor Microtub_bd PF16796.5 OQR93598.1 - 0.0021 18.0 0.0 0.018 15.0 0.0 2.3 1 1 0 1 1 1 1 Microtubule binding HALZ PF02183.18 OQR93598.1 - 0.0076 16.4 0.6 0.03 14.5 0.6 2.0 1 0 0 1 1 1 1 Homeobox associated leucine zipper Spc7 PF08317.11 OQR93598.1 - 0.016 14.1 12.5 0.03 13.2 12.5 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein HMMR_N PF15905.5 OQR93598.1 - 0.061 12.8 15.7 0.12 11.9 15.7 1.4 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal NRBF2 PF08961.10 OQR93598.1 - 0.54 9.8 7.8 0.76 9.3 6.6 1.8 1 1 1 2 2 2 0 Nuclear receptor-binding factor 2, autophagy regulator YabA PF06156.13 OQR93598.1 - 2.7 8.7 16.6 0.73 10.5 8.6 3.3 1 1 2 3 3 3 0 Initiation control protein YabA Seryl_tRNA_N PF02403.22 OQR93598.1 - 3.1 8.1 12.1 0.56 10.5 7.6 1.9 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain zf-C4H2 PF10146.9 OQR93598.1 - 3.6 7.8 13.8 0.84 9.9 10.2 1.7 2 0 0 2 2 2 0 Zinc finger-containing protein TMF_TATA_bd PF12325.8 OQR93598.1 - 4.5 7.5 16.2 2.1 8.6 13.3 2.0 2 0 0 2 2 1 0 TATA element modulatory factor 1 TATA binding DUF4200 PF13863.6 OQR93598.1 - 4.7 7.6 17.7 10 6.5 17.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) Atg14 PF10186.9 OQR93598.1 - 4.9 6.1 13.6 10 5.1 13.6 1.4 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Fib_alpha PF08702.10 OQR93598.1 - 8.3 6.6 13.9 30 4.8 13.9 2.0 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family FapA PF03961.13 OQR93598.1 - 8.4 4.9 9.9 13 4.2 9.9 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A Acetyltransf_1 PF00583.25 OQR93599.1 - 2.6e-14 53.4 0.0 3.2e-14 53.1 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 OQR93599.1 - 6.1e-09 35.9 0.0 7.9e-09 35.5 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 OQR93599.1 - 7.7e-09 35.9 0.0 1.1e-08 35.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 OQR93599.1 - 6.6e-05 23.1 0.0 8.2e-05 22.8 0.0 1.0 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 OQR93599.1 - 7e-05 22.7 0.0 0.00011 22.1 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_3 PF13302.7 OQR93599.1 - 0.00017 22.3 0.0 0.0002 22.1 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_13 PF13880.6 OQR93599.1 - 0.00054 19.9 0.0 0.00095 19.1 0.0 1.4 1 0 0 1 1 1 1 ESCO1/2 acetyl-transferase PanZ PF12568.8 OQR93599.1 - 0.0019 17.9 0.0 0.0039 16.9 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain, PanZ Acetyltransf_CG PF14542.6 OQR93599.1 - 0.13 12.4 0.0 0.23 11.6 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase MFS_1 PF07690.16 OQR93601.1 - 1.2e-39 136.3 21.7 4.8e-33 114.5 7.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 OQR93601.1 - 8.1e-09 34.8 15.7 1.1e-07 31.0 15.7 2.1 1 1 0 1 1 1 1 MFS_1 like family Sugar_tr PF00083.24 OQR93601.1 - 2.6e-07 29.9 0.1 2.6e-07 29.9 0.1 2.2 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_3 PF05977.13 OQR93601.1 - 2.8 6.2 19.7 0.19 10.1 0.7 2.7 2 1 1 3 3 3 0 Transmembrane secretion effector Pkinase PF00069.25 OQR93602.1 - 2.4e-77 259.9 0.0 3.3e-77 259.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQR93602.1 - 3.6e-33 114.9 0.0 5.4e-33 114.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OQR93602.1 - 5.3e-05 22.7 0.0 7.7e-05 22.1 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 OQR93602.1 - 0.00058 19.9 0.0 0.045 13.7 0.0 2.1 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 OQR93602.1 - 0.00083 18.2 0.0 0.0026 16.6 0.0 1.8 2 0 0 2 2 2 1 Fungal protein kinase Kdo PF06293.14 OQR93602.1 - 0.0024 17.2 0.3 0.0049 16.3 0.3 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family WaaY PF06176.11 OQR93602.1 - 0.017 14.8 0.1 0.026 14.1 0.1 1.2 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) EamA PF00892.20 OQR93603.1 - 5e-15 55.9 33.8 3.2e-13 50.0 13.1 2.2 2 0 0 2 2 2 2 EamA-like transporter family TPT PF03151.16 OQR93603.1 - 0.0031 16.9 8.5 0.0031 16.9 8.5 2.3 1 1 1 2 2 2 1 Triose-phosphate Transporter family Mt_ATP-synt_B PF05405.14 OQR93604.1 - 7e-10 38.8 11.0 4.9e-05 23.0 3.6 2.4 3 0 0 3 3 3 2 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) NleF_casp_inhib PF16809.5 OQR93604.1 - 0.0089 15.9 2.1 0.017 15.1 2.1 1.4 1 0 0 1 1 1 1 NleF caspase inhibitor MYO10_CC PF16735.5 OQR93604.1 - 0.022 14.9 4.7 1.2 9.3 0.1 2.5 2 0 0 2 2 2 0 Unconventional myosin-X coiled coil domain GIT_CC PF16559.5 OQR93605.1 - 0.086 12.7 0.6 0.086 12.7 0.6 5.6 6 1 1 7 7 7 0 GIT coiled-coil Rho guanine nucleotide exchange factor Baculo_PEP_C PF04513.12 OQR93605.1 - 1.1 9.3 15.7 0.43 10.6 1.9 4.3 2 1 1 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus KASH_CCD PF14662.6 OQR93605.1 - 2.5 7.9 53.6 0.056 13.3 17.9 3.6 3 1 1 4 4 4 0 Coiled-coil region of CCDC155 or KASH MAD PF05557.13 OQR93605.1 - 2.9 6.1 48.4 0.074 11.4 18.2 3.4 1 1 2 3 3 3 0 Mitotic checkpoint protein DUF4404 PF14357.6 OQR93605.1 - 3.2 8.5 23.6 0.15 12.7 3.3 4.5 3 1 0 4 4 4 0 Domain of unknown function (DUF4404) Fez1 PF06818.15 OQR93605.1 - 3.9 7.9 38.3 68 3.8 10.0 3.6 1 1 1 2 2 2 0 Fez1 Golgin_A5 PF09787.9 OQR93605.1 - 4.1 6.8 50.1 0.78 9.2 18.9 3.1 2 1 1 3 3 3 0 Golgin subfamily A member 5 Spc29 PF17082.5 OQR93605.1 - 9.9 5.9 23.9 1.6 8.5 4.0 3.8 1 1 1 3 3 3 0 Spindle Pole Component 29 MFS_1 PF07690.16 OQR93606.1 - 1.4e-35 122.9 17.8 1.4e-35 122.9 17.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 OQR93606.1 - 3.5e-06 26.2 8.3 3.5e-06 26.2 8.3 2.3 2 1 0 2 2 2 1 Sugar (and other) transporter MFS_1_like PF12832.7 OQR93606.1 - 3.8e-06 26.0 0.0 5.4e-05 22.2 0.0 2.3 1 1 0 1 1 1 1 MFS_1 like family MFS_3 PF05977.13 OQR93606.1 - 1.9 6.8 11.6 0.052 11.9 0.4 2.4 2 1 1 3 3 3 0 Transmembrane secretion effector DUF3586 PF12131.8 OQR93607.1 - 0.12 12.6 17.9 1.3 9.3 6.6 2.8 1 1 2 3 3 3 0 Protein of unknown function (DUF3586) EAP30 PF04157.16 OQR93608.1 - 2.4e-69 233.2 0.8 2.7e-69 233.1 0.8 1.0 1 0 0 1 1 1 1 EAP30/Vps36 family Arf PF00025.21 OQR93609.1 - 2.9e-37 127.8 0.0 3.1e-37 127.7 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.20 OQR93609.1 - 3.3e-09 36.4 0.1 2.9e-05 23.4 0.0 2.0 1 1 1 2 2 2 2 G-protein alpha subunit MMR_HSR1 PF01926.23 OQR93609.1 - 2.3e-06 27.7 0.0 2.9e-06 27.3 0.0 1.1 1 0 0 1 1 1 1 50S ribosome-binding GTPase Roc PF08477.13 OQR93609.1 - 1.3e-05 25.4 0.0 2.9e-05 24.3 0.0 1.5 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 OQR93609.1 - 2.1e-05 24.1 0.0 2.5e-05 23.8 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 OQR93609.1 - 0.0036 16.7 0.0 0.0043 16.4 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Ras PF00071.22 OQR93609.1 - 0.0073 15.9 0.0 0.0085 15.7 0.0 1.1 1 0 0 1 1 1 1 Ras family PduV-EutP PF10662.9 OQR93609.1 - 0.048 13.4 0.0 0.062 13.0 0.0 1.2 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation DUF5319 PF17252.2 OQR93609.1 - 0.064 13.5 0.0 0.11 12.7 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5319) Antibiotic_NAT PF02522.14 OQR93609.1 - 0.065 13.0 0.0 0.068 13.0 0.0 1.1 1 0 0 1 1 1 0 Aminoglycoside 3-N-acetyltransferase DUF3961 PF13106.6 OQR93609.1 - 0.17 11.6 0.9 1.3 8.7 0.1 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF3961) UcrQ PF02939.16 OQR93612.1 - 4.1e-11 42.6 0.0 7.1e-11 41.9 0.0 1.4 1 1 1 2 2 2 1 UcrQ family Cyt_b-c1_8 PF10890.8 OQR93612.1 - 6.6e-06 26.4 0.0 8.6e-06 26.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome b-c1 complex subunit 8 Phage_integrase PF00589.22 OQR93613.1 - 7.1e-05 22.7 0.1 0.00027 20.8 0.0 1.9 2 0 0 2 2 2 1 Phage integrase family Phage_int_SAM_4 PF13495.6 OQR93613.1 - 0.058 13.9 0.0 0.45 11.0 0.0 2.5 3 0 0 3 3 3 0 Phage integrase, N-terminal SAM-like domain Xpo1 PF08389.12 OQR93613.1 - 0.085 12.9 0.2 0.34 10.9 0.1 2.0 2 0 0 2 2 2 0 Exportin 1-like protein Cellulase PF00150.18 OQR93614.1 - 2.7e-30 105.7 0.3 5e-30 104.9 0.3 1.4 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) PrgH PF09480.10 OQR93614.1 - 0.026 13.9 0.0 0.039 13.3 0.0 1.2 1 0 0 1 1 1 0 Type III secretion system protein PrgH-EprH (PrgH) DUF4684 PF15736.5 OQR93614.1 - 0.028 13.1 0.6 0.041 12.6 0.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4684) PufQ PF05398.11 OQR93614.1 - 0.057 13.6 0.1 0.1 12.7 0.1 1.4 1 0 0 1 1 1 0 PufQ cytochrome subunit Abhydrolase_1 PF00561.20 OQR93615.1 - 5.2e-23 82.0 0.0 3.1e-20 72.9 0.0 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_4 PF08386.10 OQR93615.1 - 2.4e-16 59.7 0.0 9.5e-16 57.8 0.0 2.1 2 0 0 2 2 2 1 TAP-like protein Ank_2 PF12796.7 OQR93615.1 - 6.1e-12 46.0 7.7 0.00086 19.9 0.2 5.0 3 2 3 6 6 6 5 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OQR93615.1 - 5.4e-11 42.5 2.8 0.039 14.3 0.1 7.0 5 1 2 7 7 7 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 OQR93615.1 - 9e-11 42.1 2.3 0.00015 22.2 0.0 6.2 5 2 1 6 6 6 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQR93615.1 - 9.5e-06 25.6 0.5 13 6.8 0.0 6.8 7 1 1 8 8 8 1 Ankyrin repeat Ank PF00023.30 OQR93615.1 - 0.029 14.8 0.8 1.6e+02 3.0 0.0 5.5 3 2 0 3 3 3 0 Ankyrin repeat Thia_YuaJ PF09515.10 OQR93615.1 - 0.066 13.2 0.3 0.96 9.4 0.0 2.3 2 0 0 2 2 2 0 Thiamine transporter protein (Thia_YuaJ) DUF3209 PF11483.8 OQR93616.1 - 0.06 13.8 0.5 0.085 13.3 0.5 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3209) Cas9-BH PF16593.5 OQR93616.1 - 0.11 12.2 0.1 0.23 11.2 0.1 1.5 1 0 0 1 1 1 0 Bridge helix of CRISPR-associated endonuclease Cas9 DUF667 PF05018.13 OQR93617.1 - 4.9e-90 300.2 0.8 7.5e-90 299.6 0.8 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF667) Ysc84 PF04366.12 OQR93617.1 - 7.4e-32 109.8 0.3 1.4e-31 108.9 0.3 1.5 1 0 0 1 1 1 1 Las17-binding protein actin regulator tRNA-synt_2b PF00587.25 OQR93617.1 - 2.6e-27 95.9 0.0 5e-27 95.0 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.22 OQR93617.1 - 1.1e-06 28.8 1.1 2.8e-06 27.5 1.1 1.7 1 0 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain THUMP PF02926.17 OQR93618.1 - 2.3e-17 63.4 2.9 2.3e-17 63.4 2.9 2.0 1 1 1 2 2 2 1 THUMP domain Transposase_31 PF04754.12 OQR93618.1 - 0.096 12.3 0.0 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 Putative transposase, YhgA-like Ribosomal_S2 PF00318.20 OQR93618.1 - 0.17 11.1 1.4 0.18 11.0 0.1 1.8 2 0 0 2 2 2 0 Ribosomal protein S2 LANC_like PF05147.13 OQR93618.1 - 0.19 10.3 0.0 0.29 9.7 0.0 1.2 1 0 0 1 1 1 0 Lanthionine synthetase C-like protein GP67 PF17634.2 OQR93618.1 - 6.4 7.3 12.6 11 6.6 1.1 2.3 2 0 0 2 2 2 0 Gene product 67 PEPCK_ATP PF01293.20 OQR93619.1 - 4.3e-219 727.9 0.1 5.4e-219 727.6 0.1 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase DHBP_synthase PF00926.19 OQR93620.1 - 5.6e-83 277.2 0.0 7.2e-83 276.8 0.0 1.1 1 0 0 1 1 1 1 3,4-dihydroxy-2-butanone 4-phosphate synthase GTP_cyclohydro2 PF00925.20 OQR93620.1 - 0.093 12.3 0.0 11 5.6 0.0 2.4 1 1 0 2 2 2 0 GTP cyclohydrolase II PsaF PF17550.2 OQR93620.1 - 0.12 11.9 0.0 0.2 11.1 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function DUF4558 PF15104.6 OQR93621.1 - 1.4e-16 60.3 6.1 2.7e-16 59.4 6.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4558) ubiquitin PF00240.23 OQR93621.1 - 0.00057 19.6 0.0 0.0012 18.6 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family UBX PF00789.20 OQR93621.1 - 0.03 14.5 0.1 0.24 11.6 0.0 2.3 1 1 1 2 2 2 0 UBX domain Ank_2 PF12796.7 OQR93641.1 - 1.7e-54 182.3 4.1 1.5e-11 44.7 0.1 5.6 1 1 3 5 5 5 5 Ankyrin repeats (3 copies) Ank PF00023.30 OQR93641.1 - 2.8e-39 131.9 19.5 3.3e-05 24.1 0.1 9.3 8 2 3 11 11 11 8 Ankyrin repeat Ank_4 PF13637.6 OQR93641.1 - 1e-38 131.2 12.5 1.4e-08 35.1 0.0 8.1 1 1 8 9 9 9 9 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQR93641.1 - 8.4e-38 124.1 6.7 0.00042 20.5 0.0 10.3 10 1 1 11 11 11 8 Ankyrin repeat Ank_5 PF13857.6 OQR93641.1 - 1.5e-21 76.1 11.2 8.8e-06 25.9 0.1 7.5 2 1 6 8 8 8 5 Ankyrin repeats (many copies) GATase_7 PF13537.6 OQR93641.1 - 0.0014 18.5 0.0 0.39 10.6 0.0 3.1 2 1 1 3 3 3 1 Glutamine amidotransferase domain Arg_repressor PF01316.21 OQR93641.1 - 0.012 15.4 0.7 30 4.4 0.0 4.6 5 0 0 5 5 5 0 Arginine repressor, DNA binding domain Tautomerase PF01361.21 OQR93642.1 - 0.025 14.5 0.1 0.093 12.7 0.1 2.0 1 0 0 1 1 1 0 Tautomerase enzyme DUF3810 PF12725.7 OQR93642.1 - 0.09 12.1 0.9 0.14 11.5 0.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) LMBR1 PF04791.16 OQR93642.1 - 0.65 8.8 4.2 0.78 8.6 4.2 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein PAN_4 PF14295.6 OQR93643.1 - 1.9e-27 94.9 26.5 1.1e-08 34.9 2.2 4.8 4 0 0 4 4 4 4 PAN domain PAN_1 PF00024.26 OQR93643.1 - 9.9e-26 89.5 30.1 1.1e-07 31.7 2.4 4.4 4 0 0 4 4 4 4 PAN domain PAN_2 PF08276.11 OQR93643.1 - 9.3e-05 22.5 31.2 0.082 13.0 1.2 4.6 4 0 0 4 4 4 4 PAN-like domain fn3 PF00041.21 OQR93643.1 - 0.022 15.1 0.1 0.14 12.5 0.0 2.2 2 0 0 2 2 2 0 Fibronectin type III domain fn3_2 PF16893.5 OQR93643.1 - 0.075 13.2 0.1 7.6 6.8 0.0 2.5 2 0 0 2 2 2 0 Fibronectin type III domain FKBP_C PF00254.28 OQR93644.1 - 8.2e-64 212.0 0.0 1.1e-31 108.9 0.0 2.2 2 0 0 2 2 2 2 FKBP-type peptidyl-prolyl cis-trans isomerase Ank_2 PF12796.7 OQR93645.1 - 3.5e-31 107.6 6.5 8.2e-12 45.5 1.1 3.1 1 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.30 OQR93645.1 - 2.7e-26 90.8 10.8 3.2e-06 27.3 0.0 6.2 4 1 2 6 6 6 5 Ankyrin repeat Ank_4 PF13637.6 OQR93645.1 - 5.6e-19 68.3 3.3 3.8e-05 24.1 0.0 4.3 2 2 3 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQR93645.1 - 2.5e-16 58.1 4.1 0.075 13.6 0.0 6.0 6 0 0 6 6 6 4 Ankyrin repeat Ank_5 PF13857.6 OQR93645.1 - 1.6e-15 56.9 6.5 0.00047 20.4 0.1 5.1 2 1 3 5 5 5 5 Ankyrin repeats (many copies) Mqo PF06039.15 OQR93645.1 - 0.043 12.4 0.0 0.14 10.7 0.0 1.7 1 1 2 3 3 3 0 Malate:quinone oxidoreductase (Mqo) YfmQ PF10787.9 OQR93645.1 - 0.057 13.2 0.0 6.9 6.4 0.0 3.5 2 1 2 4 4 4 0 Uncharacterised protein from bacillus cereus group IL17_R_N PF15037.6 OQR93645.1 - 0.15 11.0 0.0 0.2 10.6 0.0 1.1 1 0 0 1 1 1 0 Interleukin-17 receptor extracellular region CTP_transf_1 PF01148.20 OQR93646.1 - 8.1e-68 229.1 16.6 1.3e-67 228.4 16.6 1.3 1 0 0 1 1 1 1 Cytidylyltransferase family Ank_2 PF12796.7 OQR93649.1 - 1.2e-12 48.3 9.9 3.3e-05 24.4 0.2 3.6 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQR93649.1 - 9.4e-07 29.3 6.3 0.35 11.5 0.1 5.2 2 1 3 5 5 5 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQR93649.1 - 9.4e-07 28.7 2.1 5.3 7.9 0.0 6.0 5 1 1 6 6 6 1 Ankyrin repeat Ank_5 PF13857.6 OQR93649.1 - 1.1e-05 25.7 2.6 0.18 12.2 0.0 4.9 1 1 5 6 6 6 1 Ankyrin repeats (many copies) Ank PF00023.30 OQR93649.1 - 0.00079 19.8 0.1 44 4.8 0.0 5.7 3 2 1 4 4 4 0 Ankyrin repeat PTB PF08416.13 OQR93649.1 - 0.0045 17.1 0.2 2.6 8.2 0.5 2.3 2 0 0 2 2 2 2 Phosphotyrosine-binding domain DUF5049 PF16468.5 OQR93649.1 - 0.0092 15.9 2.2 4.5 7.2 0.1 4.4 3 1 2 5 5 5 1 Domain of unknown function (DUF5049) COPIIcoated_ERV PF07970.12 OQR93649.1 - 0.11 12.4 2.4 0.1 12.4 0.4 2.0 1 1 1 2 2 2 0 Endoplasmic reticulum vesicle transporter bZIP_1 PF00170.21 OQR93651.1 - 9.8e-12 44.8 12.9 1.7e-11 44.1 12.9 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 OQR93651.1 - 1.4e-06 28.3 10.4 1.4e-06 28.3 10.4 2.2 1 1 1 2 2 2 1 Basic region leucine zipper bZIP_Maf PF03131.17 OQR93651.1 - 5.5e-06 26.8 9.0 8.9e-06 26.1 9.0 1.3 1 0 0 1 1 1 1 bZIP Maf transcription factor YabA PF06156.13 OQR93651.1 - 1.3e-05 25.7 0.0 2.5e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 Initiation control protein YabA CASP_C PF08172.12 OQR93651.1 - 8.6e-05 22.0 0.5 0.00015 21.2 0.5 1.3 1 0 0 1 1 1 1 CASP C terminal TSC22 PF01166.18 OQR93651.1 - 0.00031 21.0 1.5 0.013 15.7 0.4 2.3 1 1 1 2 2 2 2 TSC-22/dip/bun family DUF4164 PF13747.6 OQR93651.1 - 0.0063 16.8 3.3 0.012 15.9 3.3 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4164) HALZ PF02183.18 OQR93651.1 - 0.011 15.9 5.0 0.079 13.2 0.4 2.2 1 1 1 2 2 2 0 Homeobox associated leucine zipper JIP_LZII PF16471.5 OQR93651.1 - 0.013 15.7 3.4 0.029 14.5 3.4 1.6 1 0 0 1 1 1 0 JNK-interacting protein leucine zipper II TMF_TATA_bd PF12325.8 OQR93651.1 - 0.016 15.4 2.1 0.028 14.6 2.1 1.4 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding ZapB PF06005.12 OQR93651.1 - 0.019 15.4 5.2 0.02 15.3 4.1 1.6 1 1 0 1 1 1 0 Cell division protein ZapB DivIC PF04977.15 OQR93651.1 - 0.024 14.4 6.1 0.23 11.3 5.0 2.5 1 1 1 2 2 2 0 Septum formation initiator RasGAP_C PF03836.15 OQR93651.1 - 0.026 14.7 2.0 0.042 14.0 2.0 1.3 1 0 0 1 1 1 0 RasGAP C-terminus ADIP PF11559.8 OQR93651.1 - 0.03 14.4 6.9 0.047 13.8 6.9 1.3 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding EMP24_GP25L PF01105.24 OQR93651.1 - 0.03 14.3 2.2 0.03 14.3 2.2 1.7 2 0 0 2 2 2 0 emp24/gp25L/p24 family/GOLD DUF5094 PF17015.5 OQR93651.1 - 0.033 14.3 1.6 0.055 13.6 1.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5094) DUF4407 PF14362.6 OQR93651.1 - 0.034 13.5 0.7 0.052 12.9 0.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) V_ATPase_I PF01496.19 OQR93651.1 - 0.038 11.9 0.5 0.056 11.4 0.5 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family CENP-F_leu_zip PF10473.9 OQR93651.1 - 0.05 13.6 3.7 0.077 13.0 3.7 1.2 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 LPP PF04728.13 OQR93651.1 - 0.053 13.9 2.1 0.12 12.8 2.1 1.5 1 0 0 1 1 1 0 Lipoprotein leucine-zipper APG6_N PF17675.1 OQR93651.1 - 0.054 14.0 3.4 0.093 13.3 3.4 1.3 1 0 0 1 1 1 0 Apg6 coiled-coil region Cep57_CLD_2 PF14197.6 OQR93651.1 - 0.12 12.5 6.7 0.24 11.5 6.7 1.5 1 0 0 1 1 1 0 Centrosome localisation domain of PPC89 DUF2205 PF10224.9 OQR93651.1 - 0.14 12.1 2.9 0.28 11.2 2.9 1.5 1 0 0 1 1 1 0 Short coiled-coil protein Spc24 PF08286.11 OQR93651.1 - 0.18 12.1 3.4 0.2 11.9 2.2 1.7 2 0 0 2 2 1 0 Spc24 subunit of Ndc80 DUF3450 PF11932.8 OQR93651.1 - 0.2 11.0 4.1 0.29 10.4 4.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Phlebovirus_NSM PF07246.11 OQR93651.1 - 0.21 10.9 2.6 0.33 10.3 2.6 1.2 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M CtIP_N PF10482.9 OQR93651.1 - 0.26 11.3 5.2 0.35 10.9 2.3 1.9 1 1 1 2 2 2 0 Tumour-suppressor protein CtIP N-terminal domain FapA PF03961.13 OQR93651.1 - 0.41 9.2 2.1 0.57 8.7 2.1 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A TMF_DNA_bd PF12329.8 OQR93651.1 - 0.81 9.7 5.7 1.5 8.9 5.7 1.3 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding ABC2_membrane PF01061.24 OQR93652.1 - 6.5e-09 35.5 5.9 6.5e-09 35.5 5.9 1.5 2 0 0 2 2 2 1 ABC-2 type transporter ABC2_membrane_3 PF12698.7 OQR93652.1 - 0.32 10.1 8.4 0.34 10.0 8.4 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein BBS2_C PF14782.6 OQR93679.1 - 1.1e-135 452.8 3.9 1.1e-135 452.8 3.9 2.7 3 0 0 3 3 3 1 Ciliary BBSome complex subunit 2, C-terminal BBS2_Mid PF14783.6 OQR93679.1 - 8e-41 138.5 1.7 1e-38 131.7 0.1 3.7 4 0 0 4 4 4 1 Ciliary BBSome complex subunit 2, middle region BBS2_N PF14781.6 OQR93679.1 - 5.9e-36 122.6 0.7 4.6e-35 119.7 0.0 2.9 3 0 0 3 3 3 1 Ciliary BBSome complex subunit 2, N-terminal Itfg2 PF15907.5 OQR93679.1 - 2.5e-05 23.5 1.7 0.26 10.3 0.0 3.8 1 1 2 4 4 4 3 Integrin-alpha FG-GAP repeat-containing protein 2 VCBS PF13517.6 OQR93679.1 - 0.00023 21.7 1.9 0.0061 17.1 0.6 3.4 2 1 1 3 3 3 1 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.23 OQR93679.1 - 0.00064 19.8 0.9 0.0017 18.4 0.1 2.2 2 0 0 2 2 2 1 FG-GAP repeat PQQ_2 PF13360.6 OQR93679.1 - 0.038 13.6 0.0 0.2 11.2 0.0 2.0 1 1 0 1 1 1 0 PQQ-like domain MtN3_slv PF03083.16 OQR93680.1 - 5.2e-27 93.7 14.9 6.5e-16 58.2 1.1 2.2 2 0 0 2 2 2 2 Sugar efflux transporter for intercellular exchange LAB_N PF07578.11 OQR93680.1 - 0.056 13.5 0.3 0.056 13.5 0.3 2.6 2 1 0 2 2 2 0 Lipid A Biosynthesis N-terminal domain PIH1 PF08190.12 OQR93681.1 - 6.4e-32 110.3 3.1 3.8e-31 107.8 0.0 2.7 2 0 0 2 2 2 1 PIH1 N-terminal domain PIH1_CS PF18201.1 OQR93681.1 - 3.1e-16 59.6 0.1 1.9e-15 57.1 0.0 2.4 3 0 0 3 3 3 1 PIH1 CS-like domain Preseq_ALAS PF09029.10 OQR93681.1 - 0.014 15.9 1.6 0.062 13.8 1.6 2.1 1 0 0 1 1 1 0 5-aminolevulinate synthase presequence Rhabdo_M2 PF04785.12 OQR93681.1 - 0.1 11.9 0.2 4.3 6.6 0.0 2.5 2 0 0 2 2 2 0 Rhabdovirus matrix protein M2 FKBP_C PF00254.28 OQR93683.1 - 2.3e-23 82.3 0.0 2.8e-23 82.1 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase ARL2_Bind_BART PF11527.8 OQR93684.1 - 2.8e-21 75.8 7.7 4.1e-21 75.2 7.7 1.2 1 0 0 1 1 1 1 The ARF-like 2 binding protein BART DDHD PF02862.17 OQR93690.1 - 1.8e-41 142.7 3.5 1.2e-15 58.3 0.1 4.5 2 2 1 3 3 3 3 DDHD domain TPR_2 PF07719.17 OQR93690.1 - 0.0012 18.8 0.0 0.32 11.2 0.0 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 OQR93690.1 - 0.018 14.9 0.1 0.5 10.3 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat PGAP1 PF07819.13 OQR93690.1 - 0.037 13.8 0.1 0.097 12.4 0.1 1.7 1 0 0 1 1 1 0 PGAP1-like protein ACCA PF03255.14 OQR93690.1 - 4.2 7.2 6.9 42 4.0 0.5 3.4 3 0 0 3 3 3 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit Peptidase_C1 PF00112.23 OQR93691.1 - 2.1e-42 145.7 1.0 1.5e-41 142.9 0.2 2.4 2 1 0 2 2 2 1 Papain family cysteine protease Castor_Poll_mid PF06241.12 OQR93691.1 - 1.9e-27 95.2 0.0 1.9e-24 85.6 0.0 2.8 3 0 0 3 3 3 2 Castor and Pollux, part of voltage-gated ion channel Peptidase_C1_2 PF03051.15 OQR93691.1 - 0.00017 20.5 0.2 0.0096 14.7 0.0 2.3 2 0 0 2 2 2 2 Peptidase C1-like family RII_binding_1 PF10522.9 OQR93691.1 - 0.84 10.0 3.6 3.4 8.1 1.3 2.8 2 0 0 2 2 2 0 RII binding domain UL42 PF17638.2 OQR93691.1 - 5.5 7.0 5.8 2.2 8.3 0.9 2.4 2 0 0 2 2 2 0 HCMV UL42 Surp PF01805.20 OQR93692.1 - 3e-34 116.8 1.7 5.1e-17 61.6 0.2 2.5 2 0 0 2 2 2 2 Surp module PRP21_like_P PF12230.8 OQR93692.1 - 3e-25 89.4 13.6 2.6e-16 60.2 1.9 3.1 2 1 1 3 3 3 2 Pre-mRNA splicing factor PRP21 like protein ubiquitin PF00240.23 OQR93692.1 - 0.00031 20.4 0.6 0.0045 16.7 0.4 2.8 2 1 0 2 2 2 1 Ubiquitin family PAG PF15347.6 OQR93692.1 - 0.27 10.2 4.1 0.052 12.6 0.7 1.5 2 0 0 2 2 2 0 Phosphoprotein associated with glycosphingolipid-enriched Ins134_P3_kin PF05770.11 OQR93693.1 - 4.2e-33 114.6 0.1 6.4e-33 114.0 0.1 1.2 1 0 0 1 1 1 1 Inositol 1,3,4-trisphosphate 5/6-kinase ATP-grasp domain Ins134_P3_kin_N PF17927.1 OQR93693.1 - 7.2e-07 29.5 0.1 2.1e-06 28.0 0.1 1.9 1 0 0 1 1 1 1 Inositol 1,3,4-trisphosphate 5/6-kinase pre-ATP-grasp domain TTL PF03133.15 OQR93693.1 - 0.028 13.6 0.0 0.11 11.6 0.0 1.8 2 0 0 2 2 2 0 Tubulin-tyrosine ligase family 2-oxoacid_dh PF00198.23 OQR93694.1 - 3.1e-66 223.1 3.2 8.8e-66 221.7 0.2 2.0 2 0 0 2 2 2 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 OQR93694.1 - 6.9e-15 54.6 1.8 5.4e-14 51.8 1.3 2.4 2 0 0 2 2 2 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 OQR93694.1 - 1.8e-05 24.4 0.7 5.8e-05 22.8 0.1 2.2 2 0 0 2 2 2 1 Biotin-lipoyl like PYNP_C PF07831.13 OQR93694.1 - 0.087 12.5 0.1 6.7 6.4 0.0 3.2 3 0 0 3 3 3 0 Pyrimidine nucleoside phosphorylase C-terminal domain UPF0121 PF03661.13 OQR93695.1 - 9.4e-43 146.3 3.3 1.4e-42 145.7 3.3 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0121) TPR_2 PF07719.17 OQR93695.1 - 2.9e-18 64.4 3.9 2.9e-06 27.0 0.1 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.28 OQR93695.1 - 2.9e-17 61.7 3.9 1.4e-06 27.8 0.2 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 OQR93695.1 - 1.9e-12 46.6 8.2 2.2e-09 36.8 0.8 3.6 2 1 2 4 4 4 3 TPR repeat TPR_16 PF13432.6 OQR93695.1 - 6.5e-09 36.3 0.2 7.7e-05 23.3 0.1 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 OQR93695.1 - 7.7e-08 32.0 7.7 0.087 13.1 0.0 4.2 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_17 PF13431.6 OQR93695.1 - 3.7e-07 30.1 1.2 0.31 11.5 0.0 3.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 OQR93695.1 - 8.6e-07 28.6 0.2 0.0069 16.3 0.0 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 OQR93695.1 - 1.2e-05 25.7 1.2 0.074 13.6 0.1 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_10 PF13374.6 OQR93695.1 - 3e-05 23.8 2.8 0.3 11.0 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 OQR93695.1 - 3.5e-05 24.3 0.2 0.27 12.2 0.0 3.9 2 1 2 4 4 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 OQR93695.1 - 0.0002 21.6 2.1 0.089 13.1 0.3 2.9 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_3 PF07720.12 OQR93695.1 - 0.0019 18.1 0.7 0.39 10.8 0.0 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.6 OQR93695.1 - 0.0041 17.7 1.6 11 7.0 0.2 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 OQR93695.1 - 0.14 12.2 1.4 21 5.2 0.1 3.5 2 1 1 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat Pro_isomerase PF00160.21 OQR93696.1 - 3.8e-46 157.2 0.2 4.2e-46 157.1 0.2 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Thi4 PF01946.17 OQR93697.1 - 5.3e-105 349.8 0.9 7.5e-105 349.3 0.9 1.2 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.24 OQR93697.1 - 3.4e-08 33.0 1.8 1.5e-05 24.3 0.6 2.2 1 1 1 2 2 2 2 FAD binding domain DAO PF01266.24 OQR93697.1 - 9.6e-08 32.0 2.2 3.3e-06 26.9 0.8 2.1 1 1 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 OQR93697.1 - 1.1e-06 28.7 0.1 3.3e-06 27.2 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 OQR93697.1 - 6.4e-05 22.5 0.0 0.0001 21.8 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 OQR93697.1 - 0.00044 19.6 0.1 0.00077 18.8 0.1 1.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 OQR93697.1 - 0.0021 16.8 0.4 0.0036 16.1 0.4 1.4 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_3 PF01494.19 OQR93697.1 - 0.0053 16.1 0.0 0.0096 15.2 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain GMC_oxred_N PF00732.19 OQR93697.1 - 0.0057 16.1 0.0 0.11 11.9 0.0 2.1 2 0 0 2 2 2 1 GMC oxidoreductase GIDA PF01134.22 OQR93697.1 - 0.0098 15.0 2.2 0.36 9.8 0.8 2.1 2 0 0 2 2 2 1 Glucose inhibited division protein A Lycopene_cycl PF05834.12 OQR93697.1 - 0.026 13.6 0.2 0.04 13.0 0.2 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein RNA_pol_Rpb1_3 PF04983.18 OQR93697.1 - 0.044 13.7 0.0 0.064 13.2 0.0 1.3 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 3 NAD_binding_9 PF13454.6 OQR93697.1 - 0.055 13.5 0.1 0.19 11.7 0.1 1.8 2 0 0 2 2 2 0 FAD-NAD(P)-binding Pyr_redox_3 PF13738.6 OQR93697.1 - 0.056 12.7 0.0 0.093 12.0 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 OQR93697.1 - 0.071 11.9 0.4 0.12 11.2 0.4 1.3 1 0 0 1 1 1 0 Tryptophan halogenase Auto_anti-p27 PF06677.12 OQR93698.1 - 4.1e-31 106.9 14.9 2.2e-16 59.7 4.8 2.4 2 0 0 2 2 2 2 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) CxC6 PF18721.1 OQR93698.1 - 0.0018 18.5 0.4 0.57 10.5 0.1 2.4 2 0 0 2 2 2 2 CxC6 like cysteine cluster associated with KDZ transposases DUF3810 PF12725.7 OQR93698.1 - 0.0072 15.7 0.2 0.0072 15.7 0.2 1.9 1 1 1 2 2 2 1 Protein of unknown function (DUF3810) Rep_fac-A_C PF08646.10 OQR93698.1 - 0.0093 15.7 2.6 0.93 9.2 0.1 2.4 2 0 0 2 2 2 2 Replication factor-A C terminal domain DNA_ligase_A_N PF04675.14 OQR93698.1 - 0.053 13.9 0.2 0.59 10.4 0.0 2.2 2 0 0 2 2 2 0 DNA ligase N terminus zf-RRPl_C4 PF17026.5 OQR93698.1 - 0.068 13.3 1.0 3.2 7.9 0.2 2.4 2 0 0 2 2 2 0 Putative ribonucleoprotein zinc-finger pf C4 type IBR PF01485.21 OQR93698.1 - 0.077 13.2 2.9 3.3 8.0 0.3 2.7 2 0 0 2 2 2 0 IBR domain, a half RING-finger domain Ephrin_rec_like PF07699.13 OQR93698.1 - 0.11 12.3 0.1 4.8 7.0 0.1 2.4 2 0 0 2 2 2 0 Putative ephrin-receptor like zf-RRN7 PF11781.8 OQR93698.1 - 0.24 11.1 0.1 0.24 11.1 0.1 1.9 2 0 0 2 2 2 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 Peptidase_U4 PF03419.13 OQR93698.1 - 3.8 6.7 7.1 6.2 6.0 7.1 1.4 1 1 0 1 1 1 0 Sporulation factor SpoIIGA DHHC PF01529.20 OQR93699.1 - 5e-20 72.0 11.3 5e-20 72.0 11.3 2.3 2 1 0 2 2 2 1 DHHC palmitoyltransferase AA_permease_2 PF13520.6 OQR93701.1 - 3.7e-14 52.4 47.0 5.2e-14 51.9 47.0 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 OQR93701.1 - 9.4e-11 41.0 37.9 1.9e-10 39.9 37.7 1.5 1 1 0 1 1 1 1 Amino acid permease Castor_Poll_mid PF06241.12 OQR93702.1 - 3.6e-19 68.6 0.0 5.9e-15 55.1 0.0 2.6 2 0 0 2 2 2 2 Castor and Pollux, part of voltage-gated ion channel MFS_1 PF07690.16 OQR93703.1 - 1.6e-56 191.7 42.4 4.9e-52 177.0 27.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 OQR93703.1 - 1.4e-05 24.2 20.6 0.00013 21.0 20.5 2.3 1 1 0 1 1 1 1 Sugar (and other) transporter LIFR_D2 PF17971.1 OQR93703.1 - 0.028 14.6 0.0 0.075 13.2 0.0 1.7 1 1 0 1 1 1 0 Leukemia inhibitory factor receptor D2 domain Reticulon PF02453.17 OQR93703.1 - 0.16 12.0 9.3 2 8.4 0.1 3.4 3 0 0 3 3 3 0 Reticulon MMR_HSR1 PF01926.23 OQR93704.1 - 5.2e-12 45.9 0.0 8.8e-11 41.9 0.0 2.3 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 OQR93704.1 - 5.7e-06 25.9 0.0 0.0033 16.9 0.0 2.3 2 0 0 2 2 2 2 Ferrous iron transport protein B RsgA_GTPase PF03193.16 OQR93704.1 - 0.00071 19.5 0.1 0.015 15.2 0.1 2.2 1 1 0 1 1 1 1 RsgA GTPase Roc PF08477.13 OQR93704.1 - 0.0065 16.7 0.1 1 9.6 0.0 2.9 2 1 0 3 3 3 1 Ras of Complex, Roc, domain of DAPkinase Dynamin_N PF00350.23 OQR93704.1 - 0.013 15.6 0.0 0.046 13.8 0.0 1.9 2 0 0 2 2 2 0 Dynamin family Septin PF00735.18 OQR93704.1 - 0.029 13.6 0.0 0.048 12.9 0.0 1.3 1 0 0 1 1 1 0 Septin SKG6 PF08693.10 OQR93706.1 - 3.1e-05 23.3 0.7 3.1e-05 23.3 0.7 2.0 2 0 0 2 2 2 1 Transmembrane alpha-helix domain Peptidase_C1 PF00112.23 OQR93707.1 - 3.8e-79 265.8 7.7 7.5e-40 137.3 0.6 3.8 2 2 0 2 2 2 2 Papain family cysteine protease Peptidase_C1_2 PF03051.15 OQR93707.1 - 1.2e-07 30.9 6.7 0.22 10.3 0.0 4.2 4 0 0 4 4 4 4 Peptidase C1-like family PNP_UDP_1 PF01048.20 OQR93707.1 - 0.006 15.9 0.1 3.8 6.7 0.0 2.3 2 0 0 2 2 2 2 Phosphorylase superfamily HEPN_AbiA_CTD PF18732.1 OQR93707.1 - 0.013 15.5 0.0 3.5 7.6 0.0 2.3 2 0 0 2 2 2 0 HEPN like, Abia C-terminal domain DEP PF00610.21 OQR93707.1 - 0.022 14.8 0.3 6.1 7.0 0.0 2.6 2 0 0 2 2 2 0 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Uteroglobin PF01099.17 OQR93707.1 - 0.035 14.4 0.0 0.48 10.8 0.0 2.3 2 0 0 2 2 2 0 Uteroglobin family DUF5447 PF17525.2 OQR93707.1 - 0.068 13.6 0.2 11 6.5 0.0 2.9 2 0 0 2 2 2 0 Family of unknown function (DUF5447) META PF03724.16 OQR93707.1 - 0.094 12.7 0.3 10 6.1 0.0 2.7 2 0 0 2 2 2 0 META domain CEBP_ZZ PF16366.5 OQR93707.1 - 1.1 9.5 7.8 4.4 7.6 0.4 3.2 3 0 0 3 3 3 0 Cytoplasmic polyadenylation element-binding protein ZZ domain Glyco_hydro81C PF17652.1 OQR93726.1 - 1.2e-210 698.9 1.8 4.1e-108 361.7 1.0 2.3 2 0 0 2 2 2 2 Glycosyl hydrolase family 81 C-terminal domain Glyco_hydro_81 PF03639.13 OQR93726.1 - 8.2e-65 219.1 6.7 6.8e-32 110.9 0.2 2.6 3 0 0 3 3 3 2 Glycosyl hydrolase family 81 N-terminal domain HEAT PF02985.22 OQR93727.1 - 6.1e-36 119.4 46.9 0.007 16.5 0.0 22.3 25 0 0 25 25 23 9 HEAT repeat HEAT_2 PF13646.6 OQR93727.1 - 2e-26 92.2 29.3 0.04 14.3 0.1 16.0 12 5 2 16 16 15 7 HEAT repeats HEAT_EZ PF13513.6 OQR93727.1 - 6.2e-24 84.1 38.9 0.043 14.3 0.0 20.1 19 4 5 24 24 22 7 HEAT-like repeat CLASP_N PF12348.8 OQR93727.1 - 1.3e-19 70.7 0.0 0.00051 19.7 0.0 9.7 7 2 1 9 9 9 5 CLASP N terminal Cnd1 PF12717.7 OQR93727.1 - 1.8e-16 60.6 3.1 0.045 13.8 0.0 11.0 10 1 1 11 11 11 1 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 OQR93727.1 - 5.7e-11 42.9 0.0 0.89 10.2 0.0 9.7 8 1 1 9 9 9 2 Vacuolar 14 Fab1-binding region UME PF08064.13 OQR93727.1 - 2.9e-07 30.3 5.5 1.2 9.1 0.1 8.9 7 2 0 7 7 7 1 UME (NUC010) domain Adaptin_N PF01602.20 OQR93727.1 - 5.3e-07 28.6 25.4 0.58 8.7 0.3 9.0 8 2 2 11 11 11 6 Adaptin N terminal region TIP120 PF08623.10 OQR93727.1 - 1.9e-05 24.5 0.0 0.067 13.0 0.0 5.6 5 0 0 5 5 5 1 TATA-binding protein interacting (TIP20) Ecm29 PF13001.7 OQR93727.1 - 5.6e-05 22.0 1.5 0.0023 16.7 0.0 4.4 5 0 0 5 5 5 1 Proteasome stabiliser Condensin2nSMC PF12422.8 OQR93727.1 - 0.006 16.8 0.5 9.9 6.3 0.0 5.2 6 0 0 6 6 3 1 Condensin II non structural maintenance of chromosomes subunit Tti2 PF10521.9 OQR93727.1 - 0.0069 16.0 0.0 1.1 8.7 0.0 4.4 3 1 1 4 4 4 1 Tti2 family Arm PF00514.23 OQR93727.1 - 0.018 15.1 11.0 2.9 8.1 0.2 7.2 6 0 0 6 6 6 0 Armadillo/beta-catenin-like repeat Cohesin_HEAT PF12765.7 OQR93727.1 - 0.039 14.3 8.7 1e+02 3.3 0.0 7.6 7 0 0 7 7 7 0 HEAT repeat associated with sister chromatid cohesion Gcn1_N PF12074.8 OQR93727.1 - 0.18 11.1 7.9 0.68 9.2 0.3 4.9 5 0 0 5 5 5 0 Generalcontrol nonderepressible 1 (Gcn1) N-terminal DUF2019 PF09450.10 OQR93727.1 - 0.3 11.0 1.5 2.1 8.3 0.0 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF2019) Proteasome PF00227.26 OQR93728.1 - 2.3e-55 187.0 0.2 2.8e-55 186.8 0.2 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 OQR93728.1 - 1.5e-12 47.0 0.0 2.7e-12 46.1 0.0 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature DUF835 PF05763.12 OQR93729.1 - 0.11 12.3 2.3 0.98 9.2 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF835) TPR_11 PF13414.6 OQR93730.1 - 3.4e-17 61.9 14.6 1.5e-08 34.2 0.9 4.3 3 1 1 4 4 4 3 TPR repeat TPR_17 PF13431.6 OQR93730.1 - 3.2e-14 52.2 14.5 2e-06 27.8 0.5 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.28 OQR93730.1 - 7.4e-14 50.9 17.5 2e-07 30.5 0.6 4.7 4 1 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.17 OQR93730.1 - 1.3e-12 46.8 15.9 9.6e-07 28.5 0.4 4.5 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 OQR93730.1 - 3.2e-09 36.8 5.6 7.5e-05 23.2 0.3 3.5 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.6 OQR93730.1 - 4.8e-09 36.7 9.6 0.0018 18.8 0.8 3.2 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.6 OQR93730.1 - 2.9e-07 30.7 10.0 0.00043 20.5 1.7 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 OQR93730.1 - 6.1e-07 29.2 11.9 0.00028 20.9 0.1 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.6 OQR93730.1 - 7.2e-07 29.6 8.3 0.00051 20.5 0.9 2.4 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_20 PF14561.6 OQR93730.1 - 5e-06 26.8 1.8 0.0023 18.2 0.9 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat Glyco_transf_8 PF01501.20 OQR93730.1 - 0.0022 17.6 0.2 0.0082 15.7 0.0 2.0 2 0 0 2 2 2 1 Glycosyl transferase family 8 Alkyl_sulf_dimr PF14863.6 OQR93730.1 - 0.036 14.5 0.3 0.078 13.4 0.2 1.6 1 1 0 1 1 1 0 Alkyl sulfatase dimerisation Sel1 PF08238.12 OQR93730.1 - 0.056 14.2 2.8 23 5.9 0.0 3.6 3 0 0 3 3 3 0 Sel1 repeat TPR_15 PF13429.6 OQR93730.1 - 0.2 10.8 3.1 0.5 9.5 3.1 1.7 1 1 0 1 1 1 0 Tetratricopeptide repeat BTAD PF03704.17 OQR93730.1 - 0.26 11.7 3.1 2.3 8.7 3.1 2.0 1 1 0 1 1 1 0 Bacterial transcriptional activator domain TPR_6 PF13174.6 OQR93730.1 - 0.38 11.5 6.1 30 5.5 0.1 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.6 OQR93730.1 - 0.48 10.6 6.0 69 3.8 0.0 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat ANAPC3 PF12895.7 OQR93730.1 - 2.5 8.4 8.6 8.4 6.7 5.1 2.4 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 Pkinase PF00069.25 OQR93731.1 - 9.3e-72 241.6 0.0 1.3e-71 241.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQR93731.1 - 1.9e-35 122.4 0.0 2.4e-35 122.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OQR93731.1 - 4.4e-05 22.9 0.0 7.2e-05 22.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 OQR93731.1 - 0.00034 20.0 0.1 0.00076 18.9 0.1 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family LRR_8 PF13855.6 OQR93731.1 - 0.0031 17.2 0.1 0.0097 15.6 0.1 1.8 1 0 0 1 1 1 1 Leucine rich repeat APH PF01636.23 OQR93731.1 - 0.0086 16.0 0.1 0.072 13.0 0.1 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family LRR_4 PF12799.7 OQR93731.1 - 0.009 16.4 6.3 0.01 16.2 0.1 3.4 3 0 0 3 3 3 1 Leucine Rich repeats (2 copies) YrbL-PhoP_reg PF10707.9 OQR93731.1 - 0.012 15.2 0.0 0.025 14.1 0.0 1.5 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL RIO1 PF01163.22 OQR93731.1 - 0.17 11.4 0.2 0.27 10.8 0.2 1.2 1 0 0 1 1 1 0 RIO1 family OTU PF02338.19 OQR93732.1 - 1.5e-16 61.0 0.0 3.4e-16 59.9 0.0 1.6 1 0 0 1 1 1 1 OTU-like cysteine protease Peptidase_C65 PF10275.9 OQR93732.1 - 0.0025 17.3 0.0 0.12 11.8 0.0 2.3 2 0 0 2 2 2 2 Peptidase C65 Otubain Glucosamine_iso PF01182.20 OQR93745.1 - 1.8e-21 77.1 0.0 2.7e-21 76.5 0.0 1.2 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase Amidohydro_1 PF01979.20 OQR93746.1 - 5.8e-18 65.3 0.2 5.8e-18 65.3 0.2 1.7 2 1 0 2 2 2 1 Amidohydrolase family Amidohydro_3 PF07969.11 OQR93746.1 - 2.7e-08 33.7 6.0 2.5e-07 30.5 0.0 3.2 4 0 0 4 4 4 2 Amidohydrolase family Ank_2 PF12796.7 OQR93746.1 - 1e-06 29.2 1.8 2.5e-06 28.0 0.7 2.2 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OQR93746.1 - 5e-06 26.7 0.9 0.015 15.6 0.2 2.8 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 OQR93746.1 - 4.7e-05 23.9 0.2 4.7e-05 23.9 0.2 2.9 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQR93746.1 - 0.021 15.3 0.1 27 5.8 0.0 3.3 3 0 0 3 3 3 0 Ankyrin repeat UNC-93 PF05978.16 OQR93747.1 - 4.7e-14 52.4 6.1 1.2e-13 51.0 6.1 1.7 1 0 0 1 1 1 1 Ion channel regulatory protein UNC-93 MFS_1 PF07690.16 OQR93747.1 - 9.5e-14 51.1 25.1 1.5e-13 50.4 25.1 1.4 1 0 0 1 1 1 1 Major Facilitator Superfamily DCA16 PF15349.6 OQR93748.1 - 0.023 14.3 0.0 0.03 13.9 0.0 1.2 1 0 0 1 1 1 0 DDB1- and CUL4-associated factor 16 Inv-AAD PF18785.1 OQR93748.1 - 0.15 12.0 0.0 0.2 11.5 0.0 1.2 1 0 0 1 1 1 0 Invertebrate-AID/APOBEC-deaminase Proteasome PF00227.26 OQR93749.1 - 1.1e-60 204.3 0.0 1.5e-60 203.9 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 OQR93749.1 - 2.5e-10 39.8 0.4 5.9e-10 38.7 0.0 1.8 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature Pkinase PF00069.25 OQR93750.1 - 1.4e-82 277.0 0.0 1.7e-82 276.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQR93750.1 - 3.4e-38 131.4 0.0 4.4e-38 131.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OQR93750.1 - 0.00026 20.4 0.0 0.0033 16.8 0.0 2.3 2 1 0 2 2 2 1 Kinase-like Kdo PF06293.14 OQR93750.1 - 0.00058 19.3 0.0 0.00092 18.6 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Trans_reg_C PF00486.28 OQR93750.1 - 0.0024 17.9 0.0 0.0055 16.8 0.0 1.6 1 0 0 1 1 1 1 Transcriptional regulatory protein, C terminal Pkinase_fungal PF17667.1 OQR93750.1 - 0.014 14.2 0.0 0.026 13.3 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase APH PF01636.23 OQR93750.1 - 0.02 14.8 0.0 0.083 12.8 0.0 1.8 1 1 1 2 2 2 0 Phosphotransferase enzyme family DHHC PF01529.20 OQR93751.1 - 8.5e-15 55.0 34.7 3.4e-07 30.4 10.0 3.3 2 1 1 3 3 3 2 DHHC palmitoyltransferase Spt4 PF06093.13 OQR93751.1 - 0.018 15.1 2.0 0.037 14.1 2.0 1.5 1 0 0 1 1 1 0 Spt4/RpoE2 zinc finger DUF4548 PF15081.6 OQR93751.1 - 0.11 12.4 0.1 0.22 11.4 0.0 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4548) UPRTase PF14681.6 OQR93753.1 - 6.1e-66 221.8 0.0 7.3e-66 221.5 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.27 OQR93753.1 - 9.4e-05 22.0 0.0 0.00014 21.4 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain Choline_transpo PF04515.12 OQR93791.1 - 1.2e-64 218.6 31.0 1.2e-64 218.6 31.0 2.6 1 1 2 3 3 3 2 Plasma-membrane choline transporter SPC12 PF06645.13 OQR93791.1 - 3.9 7.6 7.7 0.28 11.3 0.3 3.0 3 0 0 3 3 3 0 Microsomal signal peptidase 12 kDa subunit (SPC12) CLP1_P PF16575.5 OQR93792.1 - 8e-58 195.3 0.0 1.1e-57 194.8 0.0 1.2 1 0 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop Mg_trans_NIPA PF05653.14 OQR93792.1 - 6.9e-35 120.6 16.3 6.8e-34 117.3 16.7 2.4 2 1 0 2 2 2 1 Magnesium transporter NIPA CLP1_N PF16573.5 OQR93792.1 - 2.7e-30 104.4 0.0 5.1e-30 103.5 0.0 1.5 1 0 0 1 1 1 1 N-terminal beta-sandwich domain of polyadenylation factor Clp1 PF06807.14 OQR93792.1 - 1.9e-16 60.5 0.1 3.5e-16 59.7 0.1 1.4 1 0 0 1 1 1 1 Pre-mRNA cleavage complex II protein Clp1 EamA PF00892.20 OQR93792.1 - 1.8e-06 28.2 1.9 1.8e-06 28.2 1.9 3.2 2 1 1 3 3 3 1 EamA-like transporter family DUF3392 PF11872.8 OQR93792.1 - 5.9e-05 23.3 2.6 0.00018 21.7 1.3 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF3392) AAA_29 PF13555.6 OQR93792.1 - 0.0093 15.7 0.0 0.026 14.3 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain T2SSE PF00437.20 OQR93792.1 - 0.024 13.7 0.1 0.051 12.6 0.1 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein ATP_bind_1 PF03029.17 OQR93792.1 - 0.037 13.8 0.0 0.066 13.0 0.0 1.4 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein CbiA PF01656.23 OQR93792.1 - 0.045 13.8 0.0 0.46 10.5 0.0 2.2 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_10 PF12846.7 OQR93792.1 - 0.22 10.4 0.0 0.42 9.5 0.0 1.4 1 0 0 1 1 1 0 AAA-like domain TMEM234 PF10639.9 OQR93792.1 - 3.6 7.6 8.6 0.44 10.6 0.1 3.1 4 0 0 4 4 4 0 Putative transmembrane family 234 DMT_6 PF04342.12 OQR93792.1 - 7.4 6.8 9.6 0.091 13.0 0.5 2.5 3 1 0 3 3 3 0 Putative member of DMT superfamily (DUF486) ubiquitin PF00240.23 OQR93793.1 - 8.6e-34 115.1 0.4 8.6e-34 115.1 0.4 1.5 2 0 0 2 2 2 1 Ubiquitin family Ribosomal_S30 PF04758.14 OQR93793.1 - 1.8e-28 98.5 9.6 2.9e-28 97.8 9.6 1.3 1 0 0 1 1 1 1 Ribosomal protein S30 Rad60-SLD PF11976.8 OQR93793.1 - 8.7e-16 57.5 0.7 1.5e-15 56.8 0.7 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 OQR93793.1 - 2.4e-05 24.7 0.1 0.0001 22.7 0.1 1.9 1 1 0 1 1 1 1 Ubiquitin-like domain DUF2407 PF10302.9 OQR93793.1 - 0.0012 19.4 0.5 0.0021 18.6 0.5 1.3 1 1 0 1 1 1 1 DUF2407 ubiquitin-like domain Rad60-SLD_2 PF13881.6 OQR93793.1 - 0.0057 16.7 0.8 0.022 14.9 0.8 2.1 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Sde2_N_Ubi PF13019.6 OQR93793.1 - 0.0063 16.3 0.7 0.0099 15.7 0.7 1.3 1 1 0 1 1 1 1 Silencing defective 2 N-terminal ubiquitin domain Ubiquitin_5 PF18037.1 OQR93793.1 - 0.008 16.5 0.8 0.015 15.7 0.0 1.7 2 0 0 2 2 2 1 Ubiquitin-like domain TBK1_ULD PF18396.1 OQR93793.1 - 0.0096 15.8 0.0 0.013 15.4 0.0 1.3 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain Ubiquitin_4 PF18036.1 OQR93793.1 - 0.15 12.1 2.2 7.9 6.6 0.0 2.7 3 0 0 3 3 3 0 Ubiquitin-like domain Aldedh PF00171.22 OQR93794.1 - 2e-182 606.8 0.1 2.3e-182 606.7 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Fur_reg_FbpB PF13040.6 OQR93794.1 - 0.1 12.1 0.0 0.24 11.0 0.0 1.5 1 0 0 1 1 1 0 Fur-regulated basic protein B NTP_transf_4 PF13562.6 OQR93794.1 - 0.11 12.7 0.0 0.28 11.4 0.0 1.6 1 1 0 1 1 1 0 Sugar nucleotidyl transferase Biotin_lipoyl PF00364.22 OQR93795.1 - 9.5e-09 35.0 0.1 1.6e-08 34.2 0.1 1.3 1 0 0 1 1 1 1 Biotin-requiring enzyme FYVE PF01363.21 OQR93796.1 - 1.8e-06 28.0 10.8 6.1e-06 26.3 10.8 1.9 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.16 OQR93796.1 - 0.00057 20.1 10.7 0.0018 18.5 10.7 1.8 1 0 0 1 1 1 1 FYVE-type zinc finger Siva PF05458.12 OQR93796.1 - 0.071 12.8 6.6 0.12 12.1 6.6 1.3 1 0 0 1 1 1 0 Cd27 binding protein (Siva) ThiF PF00899.21 OQR93797.1 - 2.5e-63 213.7 0.0 3.4e-63 213.3 0.0 1.1 1 0 0 1 1 1 1 ThiF family E2_bind PF08825.10 OQR93797.1 - 5.3e-19 68.1 0.0 8.2e-19 67.5 0.0 1.3 1 0 0 1 1 1 1 E2 binding domain Shikimate_DH PF01488.20 OQR93797.1 - 0.005 16.9 0.1 0.023 14.7 0.0 2.0 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase DUF2946 PF11162.8 OQR93797.1 - 0.064 13.9 0.3 0.064 13.9 0.3 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2946) Sacchrp_dh_NADP PF03435.18 OQR93797.1 - 0.075 13.3 0.6 0.32 11.2 0.0 2.3 2 2 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain Pantoate_transf PF02548.15 OQR93798.1 - 5.4e-107 357.0 0.2 6.4e-107 356.8 0.2 1.0 1 0 0 1 1 1 1 Ketopantoate hydroxymethyltransferase PEP_mutase PF13714.6 OQR93798.1 - 0.00018 21.0 0.7 0.0029 17.1 0.7 2.6 1 1 0 1 1 1 1 Phosphoenolpyruvate phosphomutase NanE PF04131.14 OQR93798.1 - 0.12 11.6 3.8 0.23 10.6 0.6 2.5 3 0 0 3 3 3 0 Putative N-acetylmannosamine-6-phosphate epimerase Lactamase_B_2 PF12706.7 OQR93811.1 - 9.7e-33 113.4 0.0 1.2e-32 113.0 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 OQR93811.1 - 8.7e-12 45.2 0.0 1.2e-11 44.8 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 OQR93811.1 - 0.067 13.2 1.1 0.32 11.0 0.4 2.1 2 0 0 2 2 2 0 Metallo-beta-lactamase superfamily TENA_THI-4 PF03070.16 OQR93819.1 - 0.011 15.6 0.0 0.023 14.5 0.0 1.5 2 0 0 2 2 2 0 TENA/THI-4/PQQC family Ribosomal_L29e PF01779.17 OQR93820.1 - 5.6e-20 71.4 10.7 5.6e-20 71.4 10.7 1.6 2 0 0 2 2 2 1 Ribosomal L29e protein family TAFII55_N PF04658.13 OQR93820.1 - 0.93 9.2 6.6 0.97 9.1 6.6 1.0 1 0 0 1 1 1 0 TAFII55 protein conserved region Rhomboid PF01694.22 OQR93821.1 - 3.6e-39 134.2 19.7 6.8e-38 130.0 17.1 2.5 3 0 0 3 3 3 1 Rhomboid family DER1 PF04511.15 OQR93821.1 - 0.00011 22.2 0.2 0.00011 22.2 0.2 1.7 2 1 0 2 2 2 1 Der1-like family IHHNV_capsid PF16530.5 OQR93821.1 - 0.013 14.6 0.0 0.019 14.1 0.0 1.2 1 0 0 1 1 1 0 Infectious hypodermal and haematopoietic necrosis virus, capsid DUF1751 PF08551.10 OQR93821.1 - 0.3 11.7 0.1 0.3 11.7 0.1 2.5 3 0 0 3 3 3 0 Eukaryotic integral membrane protein (DUF1751) START PF01852.19 OQR93823.1 - 9.2e-08 31.7 0.0 1.4e-07 31.1 0.0 1.2 1 0 0 1 1 1 1 START domain FYVE PF01363.21 OQR93823.1 - 0.00051 20.1 17.2 0.0014 18.7 17.2 1.7 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.16 OQR93823.1 - 0.0056 16.9 10.5 0.013 15.7 10.5 1.6 1 0 0 1 1 1 1 FYVE-type zinc finger zf-C2HE PF16278.5 OQR93823.1 - 0.028 14.8 9.0 0.21 12.0 0.7 3.2 2 1 1 3 3 3 0 C2HE / C2H2 / C2HC zinc-binding finger Acyl_transf_3 PF01757.22 OQR93824.1 - 3.2e-05 23.2 2.8 6.2e-05 22.2 2.8 1.5 1 1 0 1 1 1 1 Acyltransferase family SesA PF17107.5 OQR93825.1 - 0.08 13.1 0.0 0.39 10.9 0.0 2.0 2 0 0 2 2 2 0 N-terminal domain on NACHT_NTPase and P-loop NTPases SKG6 PF08693.10 OQR93826.1 - 0.0021 17.4 1.1 0.0036 16.7 1.1 1.3 1 0 0 1 1 1 1 Transmembrane alpha-helix domain zf_CCCH_5 PF18384.1 OQR93827.1 - 0.017 15.3 23.7 0.79 9.9 0.8 4.3 4 0 0 4 4 4 0 Unkempt Zinc finger domain 1 (Znf1) zf-TAZ PF02135.16 OQR93827.1 - 2.4 8.7 17.7 8.1 7.0 10.7 2.4 1 1 1 2 2 2 0 TAZ zinc finger Transp_Tc5_C PF04236.15 OQR93827.1 - 6.1 7.3 14.2 2.4 8.6 3.0 3.5 1 1 3 4 4 4 0 Tc5 transposase C-terminal domain Paf67 PF10255.9 OQR93828.1 - 6.8e-98 328.3 10.4 1.8e-97 326.9 10.4 1.6 1 1 0 1 1 1 1 RNA polymerase I-associated factor PAF67 TPR_6 PF13174.6 OQR93828.1 - 0.074 13.7 0.1 0.84 10.4 0.0 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.17 OQR93828.1 - 0.13 12.4 0.0 1.6 9.1 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF1192 PF06698.11 OQR93829.1 - 0.023 14.8 0.2 4.8 7.3 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) DcpS_C PF11969.8 OQR93831.1 - 3.5e-28 98.4 0.3 4.3e-28 98.1 0.3 1.1 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding HIT PF01230.23 OQR93831.1 - 1.7e-14 54.3 0.6 2.5e-14 53.8 0.6 1.2 1 0 0 1 1 1 1 HIT domain CwfJ_C_1 PF04677.15 OQR93831.1 - 0.17 11.8 3.2 0.46 10.4 3.1 1.8 1 1 0 1 1 1 0 Protein similar to CwfJ C-terminus 1 Jacalin PF01419.17 OQR93832.1 - 1.3e-11 44.5 0.3 4e-11 43.0 0.3 1.8 1 0 0 1 1 1 1 Jacalin-like lectin domain BP28CT PF08146.12 OQR93832.1 - 0.87 9.4 5.8 1.5 8.7 0.1 3.4 3 0 0 3 3 3 0 BP28CT (NUC211) domain Complex1_LYR PF05347.15 OQR93860.1 - 2.4e-09 37.1 1.5 3.4e-09 36.6 1.5 1.3 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 OQR93860.1 - 0.031 15.0 0.4 0.037 14.8 0.4 1.2 1 0 0 1 1 1 0 Complex1_LYR-like WD40 PF00400.32 OQR93861.1 - 5.1e-47 156.9 23.8 3.4e-08 34.0 0.1 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OQR93861.1 - 3.9e-09 36.7 1.1 0.25 11.7 0.0 5.0 1 1 2 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 OQR93861.1 - 0.0024 16.9 0.1 16 4.3 0.0 4.1 2 1 1 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 OQR93861.1 - 0.003 17.5 0.0 0.021 14.7 0.0 2.1 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.16 OQR93861.1 - 0.0032 16.0 0.1 0.25 9.8 0.1 2.5 2 1 0 3 3 3 2 Cytochrome D1 heme domain Nup160 PF11715.8 OQR93861.1 - 0.0061 15.3 6.3 0.26 9.9 0.0 4.1 3 1 1 5 5 5 1 Nucleoporin Nup120/160 WD40_like PF17005.5 OQR93861.1 - 0.055 12.8 0.0 7 5.9 0.0 2.2 2 0 0 2 2 2 0 WD40-like domain SHS2_Rpb7-N PF03876.17 OQR93862.1 - 3.8e-14 52.8 0.6 1.5e-13 50.9 0.0 2.0 2 0 0 2 2 2 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1 PF00575.23 OQR93862.1 - 9.8e-09 35.4 0.3 2.5e-08 34.1 0.3 1.7 1 0 0 1 1 1 1 S1 RNA binding domain SET PF00856.28 OQR93863.1 - 1.7e-14 54.6 0.4 4.3e-13 50.0 0.4 2.2 1 1 0 1 1 1 1 SET domain Cmc1 PF08583.10 OQR93864.1 - 1.4e-13 50.7 6.6 1.9e-13 50.2 3.3 2.6 2 0 0 2 2 2 1 Cytochrome c oxidase biogenesis protein Cmc1 like GST_C_3 PF14497.6 OQR93865.1 - 8.4e-08 32.3 0.0 1.5e-07 31.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 OQR93865.1 - 0.016 15.5 0.0 0.063 13.6 0.0 1.9 1 1 0 1 1 1 0 Glutathione S-transferase, N-terminal domain tRNA-synt_His PF13393.6 OQR93866.1 - 7e-44 150.3 0.1 9.3e-44 149.9 0.1 1.2 1 0 0 1 1 1 1 Histidyl-tRNA synthetase tRNA-synt_2b PF00587.25 OQR93866.1 - 3.3e-15 56.5 0.0 9.6e-15 55.0 0.0 1.8 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 OQR93866.1 - 1.4e-11 44.3 0.0 3.6e-11 43.1 0.0 1.7 1 0 0 1 1 1 1 Anticodon binding domain PALP PF00291.25 OQR93867.1 - 6.2e-73 245.8 0.5 7.4e-73 245.5 0.5 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Pkinase PF00069.25 OQR93868.1 - 3.8e-62 210.0 0.0 7.6e-62 209.1 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQR93868.1 - 1.7e-41 142.3 0.0 2.9e-41 141.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OQR93868.1 - 9.8e-10 38.2 0.0 1.9e-09 37.3 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 OQR93868.1 - 2.5e-06 26.6 2.0 6.2e-06 25.2 1.9 1.9 1 1 0 1 1 1 1 Fungal protein kinase APH PF01636.23 OQR93868.1 - 0.0046 16.9 0.0 0.017 15.1 0.0 1.8 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 OQR93868.1 - 0.029 13.7 0.0 0.057 12.8 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family MAP65_ASE1 PF03999.12 OQR93869.1 - 1.5e-09 37.1 2.8 1.5e-09 37.1 2.8 4.0 3 1 0 3 3 3 1 Microtubule associated protein (MAP65/ASE1 family) SAWADEE PF16719.5 OQR93869.1 - 0.0045 17.0 0.7 0.02 14.9 0.7 2.1 1 0 0 1 1 1 1 SAWADEE domain Methyltransf_14 PF08484.11 OQR93869.1 - 0.021 14.7 0.6 0.077 12.8 0.6 2.0 1 0 0 1 1 1 0 C-methyltransferase C-terminal domain SOGA PF11365.8 OQR93869.1 - 0.032 15.4 3.3 0.032 15.4 3.3 4.4 4 0 0 4 4 4 0 Protein SOGA Mlf1IP PF10248.9 OQR93870.1 - 1.4 8.8 8.8 0.97 9.4 0.4 2.5 1 1 2 3 3 3 0 Myelodysplasia-myeloid leukemia factor 1-interacting protein Kinesin PF00225.23 OQR93872.1 - 6.2e-98 327.8 0.5 7.8e-98 327.5 0.5 1.1 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 OQR93872.1 - 9.1e-26 90.6 0.0 1.2e-23 83.8 0.0 2.4 1 1 0 1 1 1 1 Microtubule binding HTH_CodY PF08222.11 OQR93872.1 - 0.014 14.9 0.3 0.035 13.6 0.1 1.7 2 0 0 2 2 2 0 CodY helix-turn-helix domain IPT PF01745.16 OQR93872.1 - 0.02 14.3 0.0 0.037 13.4 0.0 1.3 1 0 0 1 1 1 0 Isopentenyl transferase AAA_22 PF13401.6 OQR93872.1 - 0.064 13.5 0.1 0.24 11.6 0.0 2.0 2 0 0 2 2 2 0 AAA domain GAF_2 PF13185.6 OQR93894.1 - 5.5e-09 36.4 0.0 7.1e-09 36.1 0.0 1.2 1 0 0 1 1 1 1 GAF domain GAF PF01590.26 OQR93894.1 - 3.3e-05 24.5 0.0 4.9e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 GAF domain GAF_3 PF13492.6 OQR93894.1 - 0.017 15.4 0.0 0.042 14.2 0.0 1.6 1 1 0 1 1 1 0 GAF domain Glycos_transf_1 PF00534.20 OQR93896.1 - 5.7e-13 48.8 0.0 1.3e-12 47.6 0.0 1.6 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 OQR93896.1 - 3.3e-09 37.3 0.0 1.2e-08 35.5 0.0 1.8 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 OQR93896.1 - 1.7e-06 28.2 0.0 3.6e-06 27.1 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.6 OQR93896.1 - 6.9e-05 23.3 0.0 0.00018 22.0 0.0 1.6 2 0 0 2 2 2 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.6 OQR93896.1 - 0.031 14.7 0.0 0.068 13.6 0.0 1.5 1 0 0 1 1 1 0 Glycosyl transferases group 1 DUF1670 PF07900.11 OQR93896.1 - 0.22 10.8 0.0 0.34 10.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1670) Astacin PF01400.24 OQR93897.1 - 5.4e-25 88.1 5.2 2e-23 83.0 5.2 2.3 1 1 0 1 1 1 1 Astacin (Peptidase family M12A) EF-hand_7 PF13499.6 OQR93898.1 - 6.6e-37 125.8 4.7 2.9e-07 30.8 0.0 7.8 8 0 0 8 8 8 6 EF-hand domain pair EF-hand_6 PF13405.6 OQR93898.1 - 3.8e-24 82.5 0.4 0.1 12.6 0.0 12.4 13 0 0 13 13 12 5 EF-hand domain EF-hand_1 PF00036.32 OQR93898.1 - 2.2e-23 80.0 0.0 0.014 14.9 0.0 11.0 11 0 0 11 11 11 6 EF hand EF-hand_8 PF13833.6 OQR93898.1 - 4e-19 68.2 4.4 0.00052 19.8 0.0 8.0 7 3 1 8 8 8 4 EF-hand domain pair EF-hand_11 PF08976.11 OQR93898.1 - 4.1e-10 40.5 1.0 0.026 15.4 0.0 5.7 6 0 0 6 6 5 2 EF-hand domain EF-hand_9 PF14658.6 OQR93898.1 - 1.1e-07 32.1 0.2 1.9 8.8 0.0 6.7 8 0 0 8 8 8 1 EF-hand domain DUF5580 PF17743.1 OQR93898.1 - 6.9e-05 21.6 3.0 0.26 9.8 0.1 4.2 3 1 0 4 4 4 2 Family of unknown function (DUF5580) EF-hand_5 PF13202.6 OQR93898.1 - 0.00032 20.1 1.2 0.1 12.1 0.0 4.5 4 0 0 4 4 4 1 EF hand PAS_2 PF08446.11 OQR93898.1 - 0.026 15.2 0.0 0.075 13.7 0.0 1.8 1 0 0 1 1 1 0 PAS fold Lactamase_B_5 PF14597.6 OQR93898.1 - 0.037 13.5 0.0 3.1 7.2 0.0 2.3 2 0 0 2 2 2 0 Metallo-beta-lactamase superfamily EF-hand_14 PF17959.1 OQR93898.1 - 0.078 13.3 0.4 44 4.5 0.0 4.2 3 1 1 4 4 4 0 EF-hand domain vWF_A PF12450.8 OQR93898.1 - 0.08 12.9 0.0 0.28 11.2 0.0 1.9 1 0 0 1 1 1 0 von Willebrand factor AAA_assoc_C PF09821.9 OQR93898.1 - 0.25 11.9 1.2 18 5.9 0.0 4.4 6 1 0 6 6 4 0 C-terminal AAA-associated domain Ank_2 PF12796.7 OQR93914.1 - 1.1e-19 70.8 2.9 5.1e-07 30.2 0.1 3.4 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQR93914.1 - 5.4e-19 68.3 3.5 2.6e-06 27.8 0.2 4.4 3 1 1 4 4 4 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 OQR93914.1 - 6.2e-15 55.1 1.9 0.0077 16.5 0.0 5.2 1 1 3 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQR93914.1 - 8.7e-13 47.2 2.1 0.4 11.4 0.0 6.8 4 2 3 7 7 7 4 Ankyrin repeat DUF5049 PF16468.5 OQR93914.1 - 6.4e-06 26.0 0.1 12 5.9 0.0 5.8 1 1 5 6 6 6 2 Domain of unknown function (DUF5049) Trans_reg_C PF00486.28 OQR93914.1 - 0.028 14.5 0.0 26 5.0 0.0 3.3 4 0 0 4 4 4 0 Transcriptional regulatory protein, C terminal RabGAP-TBC PF00566.18 OQR93915.1 - 2.8e-37 128.5 0.1 3.8e-37 128.1 0.1 1.1 1 0 0 1 1 1 1 Rab-GTPase-TBC domain bZIP_1 PF00170.21 OQR93917.1 - 1.3 9.2 6.2 0.22 11.6 2.3 1.8 2 0 0 2 2 2 0 bZIP transcription factor PKD_channel PF08016.12 OQR93918.1 - 3.7e-53 180.7 17.4 3.7e-53 180.7 17.4 2.0 2 1 0 2 2 2 1 Polycystin cation channel Lactamase_B_2 PF12706.7 OQR93918.1 - 3.2e-13 49.6 0.2 1.9e-05 24.2 0.0 2.5 2 0 0 2 2 2 2 Beta-lactamase superfamily domain Ion_trans PF00520.31 OQR93918.1 - 4.1e-06 26.2 24.1 3.9e-05 23.0 23.2 2.2 2 0 0 2 2 2 1 Ion transport protein Lactamase_B PF00753.27 OQR93918.1 - 0.00024 21.2 0.0 0.00052 20.1 0.0 1.5 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily MHB PF16525.5 OQR93918.1 - 0.065 13.5 0.1 2.1 8.6 0.0 2.8 2 0 0 2 2 2 0 Haemophore, haem-binding Hexapep PF00132.24 OQR93919.1 - 3.1e-15 55.2 15.0 4.2e-06 26.3 0.5 4.2 3 1 1 4 4 4 4 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 OQR93919.1 - 1.2e-06 28.1 12.0 0.00013 21.6 0.9 3.7 3 1 0 3 3 3 2 Hexapeptide repeat of succinyl-transferase Fucokinase PF07959.12 OQR93919.1 - 0.0004 19.4 2.3 0.0073 15.3 0.5 2.1 1 1 1 2 2 2 2 L-fucokinase Pepsin-I3 PF06394.13 OQR93919.1 - 0.19 12.0 0.3 4 7.7 0.0 2.9 3 1 0 3 3 3 0 Pepsin inhibitor-3-like repeated domain zf-U1 PF06220.12 OQR93920.1 - 0.00026 20.7 1.2 0.00047 19.9 1.2 1.4 1 0 0 1 1 1 1 U1 zinc finger Agenet PF05641.12 OQR93920.1 - 0.0018 18.7 0.1 0.0057 17.1 0.1 1.9 1 0 0 1 1 1 1 Agenet domain AKAP95 PF04988.12 OQR93920.1 - 0.011 15.9 0.4 0.025 14.8 0.4 1.6 1 0 0 1 1 1 0 A-kinase anchoring protein 95 (AKAP95) RPA43_OB PF17875.1 OQR93920.1 - 0.14 12.8 2.9 0.3 11.7 0.4 2.4 2 0 0 2 2 2 0 RPA43 OB domain in RNA Pol I IQ PF00612.27 OQR93921.1 - 0.0019 17.8 0.7 0.02 14.6 0.7 3.0 1 0 0 1 1 1 1 IQ calmodulin-binding motif Ank PF00023.30 OQR93921.1 - 0.003 17.9 0.1 0.0084 16.5 0.1 1.8 1 0 0 1 1 1 1 Ankyrin repeat Med21 PF11221.8 OQR93921.1 - 0.017 15.4 7.1 0.078 13.2 7.1 2.2 1 0 0 1 1 1 0 Subunit 21 of Mediator complex Spc110_C PF18520.1 OQR93921.1 - 0.037 13.6 1.4 0.19 11.4 1.4 2.2 1 0 0 1 1 1 0 Spindle pole body component 110 C-terminal domain RraA-like PF03737.15 OQR93922.1 - 3.2e-40 137.7 0.3 3.8e-40 137.5 0.3 1.1 1 0 0 1 1 1 1 Aldolase/RraA Maf1 PF09174.10 OQR93932.1 - 6.9e-49 166.3 2.1 1.5e-48 165.2 2.1 1.5 1 1 0 1 1 1 1 Maf1 regulator DUF4230 PF14014.6 OQR93932.1 - 0.029 14.7 0.4 0.96 9.7 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4230) RCC1 PF00415.18 OQR93933.1 - 5.1e-69 228.7 13.5 6.2e-12 45.9 0.4 7.3 7 0 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 OQR93933.1 - 6.1e-33 111.9 44.2 5e-07 29.4 2.8 8.9 8 2 1 9 9 9 7 Regulator of chromosome condensation (RCC1) repeat NUP50 PF08911.11 OQR93933.1 - 0.032 14.9 0.0 0.06 14.0 0.0 1.3 1 0 0 1 1 1 0 NUP50 (Nucleoporin 50 kDa) DUF4094 PF13334.6 OQR93934.1 - 0.018 15.4 13.8 0.076 13.4 4.1 3.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4094) Shugoshin_N PF07558.11 OQR93934.1 - 0.09 12.7 4.0 0.51 10.3 4.0 2.4 1 0 0 1 1 1 0 Shugoshin N-terminal coiled-coil region bZIP_1 PF00170.21 OQR93934.1 - 0.56 10.3 9.0 0.41 10.8 3.2 3.4 2 0 0 2 2 2 0 bZIP transcription factor bZIP_2 PF07716.15 OQR93934.1 - 0.72 10.0 8.7 2.6 8.2 3.2 3.3 2 0 0 2 2 2 0 Basic region leucine zipper Acetyltransf_10 PF13673.7 OQR93935.1 - 2.2e-06 27.6 0.0 2.4e-06 27.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 OQR93935.1 - 6.9e-06 26.4 0.0 8e-06 26.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 OQR93935.1 - 6.2e-05 23.2 0.0 7.1e-05 23.0 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.7 OQR93935.1 - 0.00033 20.7 0.0 0.00064 19.8 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 OQR93935.1 - 0.0014 18.7 0.0 0.0015 18.7 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_6 PF13480.7 OQR93935.1 - 0.0018 18.5 0.0 0.0022 18.2 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Rbx_binding PF18113.1 OQR93935.1 - 0.13 12.1 0.1 0.38 10.6 0.1 1.8 1 1 1 2 2 2 0 Rubredoxin binding C-terminal domain Pkinase PF00069.25 OQR93936.1 - 3.5e-48 164.2 0.0 1.5e-33 116.3 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OQR93936.1 - 1.3e-30 106.6 0.0 1.5e-22 80.1 0.0 2.4 2 0 0 2 2 2 2 Protein tyrosine kinase Kdo PF06293.14 OQR93936.1 - 0.032 13.6 0.0 0.06 12.7 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DBD_Tnp_Mut PF03108.15 OQR93938.1 - 0.00092 19.1 0.5 0.0013 18.7 0.5 1.2 1 0 0 1 1 1 1 MuDR family transposase Zip PF02535.22 OQR93942.1 - 4.3e-12 45.9 9.5 6.8e-11 42.0 3.5 2.3 2 0 0 2 2 2 2 ZIP Zinc transporter Acyl_transf_3 PF01757.22 OQR93942.1 - 0.79 8.7 14.5 0.016 14.3 3.0 2.7 2 1 1 3 3 3 0 Acyltransferase family Pkinase PF00069.25 OQR93943.1 - 7.8e-49 166.4 0.0 1.1e-48 165.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQR93943.1 - 1.5e-48 165.3 0.0 2.5e-48 164.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase CD34_antigen PF06365.12 OQR93943.1 - 0.0012 18.5 0.0 0.0021 17.7 0.0 1.3 1 0 0 1 1 1 1 CD34/Podocalyxin family Pkinase_fungal PF17667.1 OQR93943.1 - 0.0019 17.0 0.0 0.0032 16.3 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase SKG6 PF08693.10 OQR93943.1 - 0.0081 15.5 0.1 0.019 14.4 0.1 1.6 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Haspin_kinase PF12330.8 OQR93943.1 - 0.017 14.0 0.3 0.044 12.7 0.1 1.9 1 1 0 1 1 1 0 Haspin like kinase domain APH PF01636.23 OQR93943.1 - 0.16 11.9 0.0 0.71 9.8 0.0 2.0 1 1 0 2 2 2 0 Phosphotransferase enzyme family Histone PF00125.24 OQR93946.1 - 1.4e-20 74.0 0.1 1.7e-20 73.7 0.1 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID_20kDa PF03847.13 OQR93946.1 - 0.00022 21.6 0.0 0.00036 21.0 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A CBFD_NFYB_HMF PF00808.23 OQR93946.1 - 0.0017 18.6 0.7 0.0034 17.6 0.0 1.8 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone YscO-like PF16789.5 OQR93946.1 - 0.014 15.4 0.0 0.016 15.3 0.0 1.1 1 0 0 1 1 1 0 YscO-like protein MRP-S28 PF10213.9 OQR93947.1 - 4.3e-13 49.8 0.4 8.4e-13 48.8 0.2 1.6 2 0 0 2 2 2 1 Mitochondrial ribosomal subunit protein Steroid_dh PF02544.16 OQR93948.1 - 2.2e-51 173.8 1.2 2.2e-51 173.8 1.2 2.4 3 0 0 3 3 3 1 3-oxo-5-alpha-steroid 4-dehydrogenase CorA PF01544.18 OQR93948.1 - 7.9e-45 153.4 5.2 2e-39 135.6 2.9 2.2 2 0 0 2 2 2 2 CorA-like Mg2+ transporter protein DUF1295 PF06966.12 OQR93948.1 - 4.8e-05 23.0 0.1 9.8e-05 22.0 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) EF-hand_6 PF13405.6 OQR93948.1 - 0.033 14.1 0.0 0.091 12.7 0.0 1.8 1 0 0 1 1 1 0 EF-hand domain CCDC142 PF14923.6 OQR93948.1 - 0.086 11.6 0.0 0.13 10.9 0.0 1.3 1 0 0 1 1 1 0 Coiled-coil protein 142 FIST_C PF10442.9 OQR93949.1 - 9.1e-10 38.6 0.0 4.4e-09 36.4 0.0 2.1 2 1 0 2 2 2 1 FIST C domain F-box-like PF12937.7 OQR93949.1 - 0.002 18.0 0.5 0.0042 17.0 0.0 1.8 2 0 0 2 2 2 1 F-box-like FIST PF08495.10 OQR93949.1 - 0.056 13.5 0.1 1.9 8.4 0.0 2.5 2 1 0 2 2 2 0 FIST N domain Coatomer_E PF04733.14 OQR93950.1 - 1.7e-72 244.3 1.0 1.9e-72 244.1 1.0 1.0 1 0 0 1 1 1 1 Coatomer epsilon subunit TPR_1 PF00515.28 OQR93950.1 - 0.00011 21.8 0.4 0.13 12.1 0.2 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.6 OQR93950.1 - 0.00092 19.8 3.4 0.064 14.1 0.1 4.3 3 1 2 5 5 5 1 Tetratricopeptide repeat TPR_2 PF07719.17 OQR93950.1 - 0.0037 17.3 0.4 0.0037 17.3 0.4 4.4 5 0 0 5 5 5 1 Tetratricopeptide repeat AstA PF04958.12 OQR93950.1 - 0.0039 15.8 0.0 0.0074 14.9 0.0 1.4 1 0 0 1 1 1 1 Arginine N-succinyltransferase beta subunit TPR_19 PF14559.6 OQR93950.1 - 0.041 14.4 0.5 0.041 14.4 0.5 4.5 4 2 1 5 5 5 0 Tetratricopeptide repeat TPR_10 PF13374.6 OQR93950.1 - 0.094 12.6 1.0 0.33 10.9 1.0 2.0 1 0 0 1 1 1 0 Tetratricopeptide repeat Cas_Csm6 PF09659.10 OQR93950.1 - 0.12 11.1 0.5 0.22 10.3 0.1 1.5 2 0 0 2 2 2 0 CRISPR-associated protein (Cas_Csm6) TPR_16 PF13432.6 OQR93950.1 - 0.97 10.1 6.8 0.56 10.9 0.3 3.5 2 2 1 3 3 3 0 Tetratricopeptide repeat DnaJ PF00226.31 OQR93951.1 - 2.6e-28 97.9 1.6 3.8e-28 97.4 1.6 1.3 1 0 0 1 1 1 1 DnaJ domain Histone_H2A_C PF16211.5 OQR93952.1 - 3.1e-19 68.4 1.4 5.9e-19 67.5 1.4 1.5 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 OQR93952.1 - 3.4e-16 59.8 0.0 4.2e-16 59.5 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 OQR93952.1 - 9.9e-05 22.5 0.0 0.00013 22.2 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone VPS9 PF02204.18 OQR93953.1 - 2.7e-07 30.8 0.1 8.1e-07 29.2 0.1 1.9 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain Rep-A_N PF04057.12 OQR93977.1 - 1.4e-15 57.1 0.1 1.3e-14 54.0 0.0 2.1 2 0 0 2 2 2 1 Replication factor-A protein 1, N-terminal domain BTB_2 PF02214.22 OQR93977.1 - 7.7e-11 42.2 0.1 1.5e-10 41.2 0.0 1.6 2 0 0 2 2 2 1 BTB/POZ domain BTB PF00651.31 OQR93977.1 - 0.0099 16.1 0.1 0.035 14.3 0.0 1.9 2 1 0 2 2 2 1 BTB/POZ domain TPP1 PF10341.9 OQR93977.1 - 0.01 15.8 0.0 0.021 14.8 0.0 1.6 1 0 0 1 1 1 0 Shelterin complex subunit, TPP1/ACD CEBP_ZZ PF16366.5 OQR93978.1 - 0.00013 22.1 3.9 0.00033 20.8 3.9 1.6 1 0 0 1 1 1 1 Cytoplasmic polyadenylation element-binding protein ZZ domain IQ PF00612.27 OQR93978.1 - 0.0015 18.1 16.3 0.035 13.9 1.0 4.7 4 0 0 4 4 4 2 IQ calmodulin-binding motif zf-B_box PF00643.24 OQR93978.1 - 0.0037 17.4 5.8 0.0075 16.4 5.8 1.4 1 0 0 1 1 1 1 B-box zinc finger BTB_2 PF02214.22 OQR93979.1 - 1e-13 51.4 0.0 2.5e-13 50.2 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain SPRY PF00622.28 OQR93979.1 - 4.9e-07 29.9 0.0 7.8e-07 29.2 0.0 1.4 1 0 0 1 1 1 1 SPRY domain Neuralized PF07177.12 OQR93979.1 - 0.0078 16.2 0.0 0.015 15.3 0.0 1.6 1 1 0 1 1 1 1 Neuralized BTB PF00651.31 OQR93979.1 - 0.059 13.6 0.0 0.11 12.7 0.0 1.4 1 0 0 1 1 1 0 BTB/POZ domain Nodulin_late PF07127.11 OQR93980.1 - 0.013 15.8 1.1 0.013 15.8 1.1 3.3 3 0 0 3 3 3 0 Late nodulin protein Disintegrin PF00200.23 OQR93981.1 - 4.1e-12 46.7 92.5 0.005 17.6 5.8 7.5 4 4 1 5 5 5 5 Disintegrin Nodulin_late PF07127.11 OQR93981.1 - 0.0025 18.1 1.9 0.0025 18.1 1.9 6.5 6 4 2 8 8 8 1 Late nodulin protein TFIIS_M PF07500.14 OQR93996.1 - 4.4e-17 62.6 4.5 9.2e-17 61.5 4.5 1.5 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS), central domain TFIIS_C PF01096.18 OQR93996.1 - 5.3e-17 61.4 3.9 1.1e-16 60.4 3.9 1.5 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS) Med26 PF08711.11 OQR93996.1 - 1.4e-12 47.5 1.4 4.5e-12 45.8 1.4 2.0 1 0 0 1 1 1 1 TFIIS helical bundle-like domain zf-DNL PF05180.12 OQR93996.1 - 0.027 14.4 0.8 0.085 12.8 0.8 1.8 1 0 0 1 1 1 0 DNL zinc finger zinc_ribbon_6 PF14599.6 OQR93996.1 - 6.1 6.9 7.2 5.2 7.2 0.3 3.0 3 0 0 3 3 3 0 Zinc-ribbon IF4E PF01652.18 OQR93997.1 - 1.1e-39 135.8 0.0 1.3e-39 135.5 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E CH PF00307.31 OQR93998.1 - 3.7e-18 65.7 2.0 5.7e-05 23.3 0.1 4.8 5 0 0 5 5 5 4 Calponin homology (CH) domain CH_2 PF06294.11 OQR93998.1 - 0.01 16.0 0.6 3.5 7.8 0.0 4.2 5 0 0 5 5 5 0 CH-like domain in sperm protein TPKR_C2 PF16920.5 OQR93998.1 - 0.15 12.2 0.1 0.55 10.4 0.1 2.0 1 0 0 1 1 1 0 Tyrosine-protein kinase receptor C2 Ig-like domain Pox_MCEL PF03291.16 OQR93999.1 - 1.5e-41 142.6 0.2 1.4e-32 113.1 0.0 2.4 2 0 0 2 2 2 2 mRNA capping enzyme Peptidase_S9 PF00326.21 OQR93999.1 - 2e-39 135.3 0.0 3.8e-39 134.4 0.0 1.5 1 0 0 1 1 1 1 Prolyl oligopeptidase family Methyltransf_25 PF13649.6 OQR93999.1 - 5e-10 40.0 0.4 3e-08 34.3 0.4 2.6 1 1 0 1 1 1 1 Methyltransferase domain DLH PF01738.18 OQR93999.1 - 6e-09 35.8 0.0 4.1e-08 33.0 0.0 2.2 1 1 0 1 1 1 1 Dienelactone hydrolase family Methyltransf_12 PF08242.12 OQR93999.1 - 1.7e-08 35.1 0.0 3.8e-08 34.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OQR93999.1 - 4.1e-08 33.2 0.0 9e-08 32.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Peptidase_S15 PF02129.18 OQR93999.1 - 8.4e-08 32.1 1.0 8.4e-08 32.1 1.0 2.8 3 0 0 3 3 3 1 X-Pro dipeptidyl-peptidase (S15 family) Methyltransf_11 PF08241.12 OQR93999.1 - 1.8e-06 28.5 0.2 6.1e-05 23.6 0.2 2.5 1 1 0 1 1 1 1 Methyltransferase domain Hydrolase_4 PF12146.8 OQR93999.1 - 7.5e-06 25.4 0.3 0.0024 17.2 0.2 2.5 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 OQR93999.1 - 1.1e-05 26.1 0.3 2.6e-05 24.9 0.3 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Methyltransf_23 PF13489.6 OQR93999.1 - 1.6e-05 24.8 0.1 9.2e-05 22.3 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Abhydrolase_3 PF07859.13 OQR93999.1 - 2.4e-05 24.3 0.4 0.00059 19.8 0.4 2.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold WW PF00397.26 OQR93999.1 - 0.00011 22.2 1.7 0.00011 22.2 1.7 2.8 3 0 0 3 3 2 1 WW domain Esterase PF00756.20 OQR93999.1 - 0.00018 21.2 0.1 0.00064 19.4 0.1 1.9 1 0 0 1 1 1 1 Putative esterase TPMT PF05724.11 OQR93999.1 - 0.0013 18.4 0.0 0.0044 16.7 0.0 1.8 2 0 0 2 2 2 1 Thiopurine S-methyltransferase (TPMT) BAAT_C PF08840.11 OQR93999.1 - 0.0021 18.0 0.0 0.036 14.0 0.0 2.3 1 1 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal LIP PF03583.14 OQR93999.1 - 0.02 14.2 1.1 0.066 12.5 0.9 1.8 2 0 0 2 2 2 0 Secretory lipase Methyltransf_4 PF02390.17 OQR93999.1 - 0.037 13.5 0.0 0.072 12.6 0.0 1.5 1 0 0 1 1 1 0 Putative methyltransferase PD40 PF07676.12 OQR93999.1 - 0.057 13.4 0.0 0.14 12.2 0.0 1.7 1 0 0 1 1 1 0 WD40-like Beta Propeller Repeat COesterase PF00135.28 OQR93999.1 - 1.2 7.9 4.6 0.19 10.5 0.2 1.7 2 0 0 2 2 2 0 Carboxylesterase family LIDHydrolase PF10230.9 OQR94003.1 - 2.4e-48 165.0 0.9 4e-48 164.3 0.9 1.4 1 0 0 1 1 1 1 Lipid-droplet associated hydrolase Fringe PF02434.16 OQR94003.1 - 6.3e-12 45.5 0.8 1.3e-11 44.5 0.8 1.4 1 0 0 1 1 1 1 Fringe-like Abhydrolase_1 PF00561.20 OQR94003.1 - 3.1e-08 33.6 0.0 5.8e-08 32.7 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 OQR94003.1 - 5e-08 32.5 0.0 8.6e-08 31.7 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 OQR94003.1 - 1.9e-06 28.7 0.0 5e-06 27.3 0.0 1.7 1 0 0 1 1 1 1 Alpha/beta hydrolase family Galactosyl_T PF01762.21 OQR94003.1 - 1.1e-05 25.3 0.5 3.2e-05 23.9 0.5 1.8 1 0 0 1 1 1 1 Galactosyltransferase Ser_hydrolase PF06821.13 OQR94003.1 - 0.008 16.0 0.1 0.067 13.0 0.0 2.2 2 0 0 2 2 2 1 Serine hydrolase Lipase_3 PF01764.25 OQR94003.1 - 0.025 14.4 0.0 0.21 11.4 0.0 2.1 2 0 0 2 2 2 0 Lipase (class 3) Lipase PF00151.19 OQR94003.1 - 0.061 12.6 0.0 0.1 11.9 0.0 1.2 1 0 0 1 1 1 0 Lipase Esterase PF00756.20 OQR94003.1 - 0.11 12.1 0.0 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 Putative esterase DUF1294 PF06961.13 OQR94003.1 - 0.13 12.6 0.0 0.31 11.3 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1294) BAAT_C PF08840.11 OQR94003.1 - 0.15 12.0 0.0 0.44 10.4 0.0 1.9 1 1 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Sec1 PF00995.23 OQR94004.1 - 6.3e-15 55.4 0.0 7e-08 32.2 0.0 2.2 2 0 0 2 2 2 2 Sec1 family DUF1566 PF07603.11 OQR94004.1 - 0.085 13.2 0.0 0.22 11.9 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1566) AA_permease_2 PF13520.6 OQR94015.1 - 6.5e-62 209.7 73.3 1e-41 143.2 41.9 2.6 2 1 0 2 2 2 2 Amino acid permease AA_permease PF00324.21 OQR94015.1 - 8.9e-44 149.9 65.6 1.7e-27 96.2 39.2 2.3 2 0 0 2 2 2 2 Amino acid permease AA_permease_C PF13906.6 OQR94015.1 - 3.2e-10 39.9 4.8 3.2e-10 39.9 4.8 3.1 2 0 0 2 2 2 1 C-terminus of AA_permease WW PF00397.26 OQR94015.1 - 1.9e-05 24.6 0.1 5.4e-05 23.2 0.1 1.8 1 0 0 1 1 1 1 WW domain IQ PF00612.27 OQR94015.1 - 4.2e-05 23.0 94.9 0.027 14.2 0.2 14.7 14 0 0 14 14 14 9 IQ calmodulin-binding motif DUF3382 PF11862.8 OQR94015.1 - 3.4 8.0 6.3 3.9 7.8 0.2 3.9 3 0 0 3 3 3 0 Domain of unknown function (DUF3382) Ribosomal_S2 PF00318.20 OQR94016.1 - 2e-25 89.3 0.2 1.8e-12 46.9 0.1 2.6 1 1 1 2 2 2 2 Ribosomal protein S2 AMP-binding PF00501.28 OQR94016.1 - 1.4e-07 30.5 0.1 0.01 14.4 0.1 2.7 2 1 0 2 2 2 2 AMP-binding enzyme AMP-binding_C PF13193.6 OQR94016.1 - 0.0092 16.9 0.1 0.026 15.5 0.1 1.9 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Proton_antipo_C PF01010.19 OQR94016.1 - 0.025 14.2 0.2 0.05 13.2 0.2 1.5 1 0 0 1 1 1 0 NADH-dehyrogenase subunit F, TMs, (complex I) C-terminus 40S_SA_C PF16122.5 OQR94016.1 - 0.035 15.5 10.0 0.035 15.5 10.0 2.6 2 1 0 2 2 2 0 40S ribosomal protein SA C-terminus ARGLU PF15346.6 OQR94016.1 - 2.6 7.9 7.4 2.5 8.0 4.1 2.1 2 0 0 2 2 2 0 Arginine and glutamate-rich 1 BiPBP_C PF06832.12 OQR94017.1 - 0.0097 15.9 0.0 0.021 14.8 0.0 1.5 1 0 0 1 1 1 1 Penicillin-Binding Protein C-terminus Family LMWPc PF01451.21 OQR94018.1 - 8.6e-29 100.7 0.2 8.4e-28 97.5 0.2 2.0 1 1 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase zf-HC5HC2H_2 PF13832.6 OQR94018.1 - 0.027 14.6 0.1 0.049 13.8 0.1 1.4 1 0 0 1 1 1 0 PHD-zinc-finger like domain DUF2024 PF09630.10 OQR94018.1 - 0.1 12.5 0.1 0.61 10.0 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF2024) Aminotran_5 PF00266.19 OQR94019.1 - 7.1e-35 120.6 0.0 1.4e-34 119.7 0.0 1.5 1 0 0 1 1 1 1 Aminotransferase class-V ATP_bind_3 PF01171.20 OQR94019.1 - 1.6e-16 60.6 0.1 4.4e-16 59.2 0.0 1.7 2 0 0 2 2 2 1 PP-loop family Ribosomal_L7Ae PF01248.26 OQR94020.1 - 1.2e-23 82.7 0.0 2.1e-23 81.9 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RRP7 PF12923.7 OQR94020.1 - 3.4e-22 78.8 20.8 5.3e-22 78.2 20.8 1.3 1 0 0 1 1 1 1 Ribosomal RNA-processing protein 7 (RRP7) C-terminal domain RRM_1 PF00076.22 OQR94020.1 - 5.5e-05 22.9 0.0 0.00015 21.5 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_Rrp7 PF17799.1 OQR94020.1 - 9.6e-05 22.2 0.0 0.00073 19.4 0.0 2.0 1 1 1 2 2 2 1 Rrp7 RRM-like N-terminal domain zf-HC5HC2H_2 PF13832.6 OQR94021.1 - 5.5e-30 103.8 8.2 1.3e-27 96.1 0.2 2.4 2 0 0 2 2 2 2 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 OQR94021.1 - 3.3e-22 78.5 7.8 3.3e-19 68.9 0.0 3.2 3 0 0 3 3 3 2 PHD-like zinc-binding domain PHD PF00628.29 OQR94021.1 - 3.9e-06 26.7 28.3 7.2e-05 22.6 7.7 4.1 4 1 0 4 4 4 2 PHD-finger PHD_2 PF13831.6 OQR94021.1 - 0.00019 20.9 1.0 0.00019 20.9 1.0 3.9 3 0 0 3 3 3 1 PHD-finger BET PF17035.5 OQR94021.1 - 0.0013 18.8 0.0 0.55 10.4 0.1 2.4 2 0 0 2 2 2 2 Bromodomain extra-terminal - transcription regulation zf-RING-like PF08746.11 OQR94021.1 - 0.0034 17.7 24.7 0.029 14.7 3.0 2.9 3 0 0 3 3 3 2 RING-like domain Prok-RING_1 PF14446.6 OQR94021.1 - 0.0094 15.9 0.4 0.0094 15.9 0.4 2.9 3 0 0 3 3 3 1 Prokaryotic RING finger family 1 FANCL_C PF11793.8 OQR94021.1 - 0.24 11.6 17.4 0.17 12.1 0.5 2.8 2 0 0 2 2 2 0 FANCL C-terminal domain zf-RING_2 PF13639.6 OQR94021.1 - 0.56 10.6 23.7 0.25 11.7 9.1 3.5 3 0 0 3 3 3 0 Ring finger domain EI24 PF07264.11 OQR94022.1 - 5e-44 150.7 34.8 1.8e-23 83.7 10.2 2.1 2 0 0 2 2 2 2 Etoposide-induced protein 2.4 (EI24) DUF2428 PF10350.9 OQR94023.1 - 6.6e-45 153.5 2.9 8.9e-45 153.1 0.3 2.6 2 0 0 2 2 2 1 Putative death-receptor fusion protein (DUF2428) BTB_2 PF02214.22 OQR94030.1 - 3.7e-25 88.1 0.2 7.2e-12 45.5 0.0 2.7 2 0 0 2 2 2 2 BTB/POZ domain Nsp1_C PF05064.13 OQR94030.1 - 9.6e-19 67.3 1.7 9.6e-19 67.3 1.7 2.2 2 0 0 2 2 2 1 Nsp1-like C-terminal region LMBR1 PF04791.16 OQR94030.1 - 0.4 9.5 5.4 1 8.2 5.4 1.6 1 0 0 1 1 1 0 LMBR1-like membrane protein SMC_N PF02463.19 OQR94032.1 - 0.15 11.5 0.4 0.17 11.3 0.4 1.1 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain OST3_OST6 PF04756.13 OQR94033.1 - 3.4e-24 85.7 0.9 1e-23 84.1 0.9 1.8 1 1 0 1 1 1 1 OST3 / OST6 family, transporter family RasGEF PF00617.19 OQR94034.1 - 1.5e-32 113.2 0.0 3e-32 112.2 0.0 1.5 1 0 0 1 1 1 1 RasGEF domain Ank_2 PF12796.7 OQR94034.1 - 8.9e-30 103.1 0.8 1.7e-08 34.9 0.1 5.0 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.30 OQR94034.1 - 8.4e-24 82.9 5.6 0.00081 19.7 0.0 8.2 8 0 0 8 8 8 5 Ankyrin repeat Ank_4 PF13637.6 OQR94034.1 - 2.6e-22 78.9 1.1 4.5e-06 27.1 0.0 5.8 3 2 3 6 6 6 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 OQR94034.1 - 6e-22 77.4 2.9 1.2e-05 25.5 0.1 7.6 5 2 2 7 7 7 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQR94034.1 - 4e-20 69.8 0.4 0.057 14.0 0.0 8.4 7 0 0 7 7 7 4 Ankyrin repeat PH PF00169.29 OQR94034.1 - 6.9e-13 49.0 1.4 1e-12 48.5 0.2 1.9 2 0 0 2 2 2 1 PH domain VPS9 PF02204.18 OQR94034.1 - 0.00017 21.7 0.0 0.00049 20.3 0.0 1.9 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain PDZ PF00595.24 OQR94034.1 - 0.0019 18.5 0.0 0.0046 17.3 0.0 1.6 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 OQR94034.1 - 0.0086 15.9 0.0 0.026 14.4 0.0 1.8 1 0 0 1 1 1 1 PDZ domain zf-HIT PF04438.16 OQR94034.1 - 0.33 10.9 15.3 2.7 7.9 1.6 2.7 2 0 0 2 2 2 0 HIT zinc finger Pkinase PF00069.25 OQR94035.1 - 1.7e-59 201.3 0.0 2e-59 201.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQR94035.1 - 3.4e-25 88.8 0.0 4.8e-25 88.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Glycos_trans_3N PF02885.17 OQR94035.1 - 0.0029 17.4 0.0 0.0058 16.4 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family, helical bundle domain APH PF01636.23 OQR94035.1 - 0.0039 17.1 0.0 0.0079 16.1 0.0 1.6 2 0 0 2 2 2 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 OQR94035.1 - 0.008 15.2 0.1 0.011 14.7 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 OQR94035.1 - 0.0097 15.2 0.0 0.018 14.4 0.0 1.4 1 1 0 1 1 1 1 Kinase-like Pox_ser-thr_kin PF05445.11 OQR94035.1 - 0.063 12.2 0.0 0.095 11.7 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Kdo PF06293.14 OQR94035.1 - 0.066 12.6 0.1 0.096 12.0 0.1 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.11 OQR94035.1 - 0.076 12.1 0.0 0.11 11.5 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 FTA2 PF13095.6 OQR94035.1 - 0.11 12.1 0.0 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 TF_Zn_Ribbon PF08271.12 OQR94036.1 - 0.016 14.7 3.2 0.08 12.5 0.2 2.5 2 0 0 2 2 2 0 TFIIB zinc-binding zf-HIT PF04438.16 OQR94036.1 - 0.071 13.0 16.4 0.12 12.3 1.0 2.4 2 1 0 2 2 2 0 HIT zinc finger zf_UBZ PF18439.1 OQR94036.1 - 0.52 10.0 3.2 3.9 7.2 0.3 2.7 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger Rubredoxin_2 PF18073.1 OQR94036.1 - 0.73 9.6 6.3 4.5 7.1 0.3 2.5 2 0 0 2 2 2 0 Rubredoxin metal binding domain zf-ribbon_3 PF13248.6 OQR94036.1 - 0.84 9.1 13.5 2.2 7.8 2.7 3.4 2 2 1 3 3 3 0 zinc-ribbon domain Desulfoferrod_N PF06397.12 OQR94036.1 - 7.6 6.2 10.4 25 4.6 4.2 2.8 2 1 0 2 2 2 0 Desulfoferrodoxin, N-terminal domain RecR PF02132.15 OQR94036.1 - 8 6.1 8.1 21 4.8 0.3 2.3 2 0 0 2 2 2 0 RecR protein Lipase_GDSL_2 PF13472.6 OQR94037.1 - 3e-26 92.9 0.0 4e-26 92.5 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 OQR94037.1 - 3.7e-17 63.0 0.0 6.6e-17 62.2 0.0 1.4 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_3 PF14606.6 OQR94037.1 - 0.13 12.4 0.0 0.21 11.7 0.0 1.4 1 1 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family WD40 PF00400.32 OQR94054.1 - 3.3e-15 56.2 11.8 2e-05 25.3 0.8 7.5 7 0 0 7 7 7 4 WD domain, G-beta repeat Myb_DNA-binding PF00249.31 OQR94054.1 - 1.7e-12 47.3 0.1 3.7e-12 46.2 0.1 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain ANAPC4_WD40 PF12894.7 OQR94054.1 - 3.7e-09 36.8 0.1 5.5e-05 23.4 0.0 4.5 4 0 0 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain RWP-RK PF02042.15 OQR94054.1 - 7.1e-05 22.7 2.3 0.00014 21.8 2.3 1.5 1 0 0 1 1 1 1 RWP-RK domain Myb_DNA-bind_7 PF15963.5 OQR94054.1 - 0.0018 18.1 0.1 0.0047 16.8 0.1 1.6 1 0 0 1 1 1 1 Myb DNA-binding like Myb_DNA-bind_6 PF13921.6 OQR94054.1 - 0.0069 16.6 0.0 0.038 14.3 0.1 2.2 2 0 0 2 2 2 1 Myb-like DNA-binding domain tRNA-synt_2 PF00152.20 OQR94055.1 - 6.6e-54 183.1 0.0 5e-34 117.8 0.0 3.1 1 1 1 2 2 2 2 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 OQR94055.1 - 2.4e-12 46.6 0.0 4.4e-12 45.8 0.0 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 OQR94055.1 - 0.0008 19.0 0.1 0.046 13.2 0.0 2.5 2 0 0 2 2 2 1 tRNA synthetases class II core domain (F) Cys_rich_FGFR PF00839.17 OQR94055.1 - 0.0099 16.0 0.1 0.029 14.5 0.0 1.7 2 0 0 2 2 2 1 Cysteine rich repeat Choline_transpo PF04515.12 OQR94056.1 - 2.8e-75 253.5 27.9 2.8e-75 253.5 27.9 2.4 1 1 2 3 3 3 1 Plasma-membrane choline transporter 2OG-FeII_Oxy_3 PF13640.6 OQR94057.1 - 6e-10 39.9 0.0 1.3e-09 38.8 0.0 1.5 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily COMM_domain PF07258.14 OQR94058.1 - 1.9e-09 37.5 0.1 3.6e-09 36.6 0.1 1.5 1 0 0 1 1 1 1 COMM domain SCAB-Ig PF16709.5 OQR94072.1 - 0.086 12.9 0.0 0.2 11.8 0.0 1.6 1 0 0 1 1 1 0 Ig domain of plant-specific actin-binding protein RNA_pol_Rpb2_6 PF00562.28 OQR94074.1 - 1.4e-114 383.2 0.4 2.7e-114 382.3 0.4 1.4 1 1 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 OQR94074.1 - 1e-36 126.4 0.0 1.7e-36 125.7 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_3 PF04565.16 OQR94074.1 - 1.4e-28 98.9 0.0 3.6e-28 97.5 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_7 PF04560.20 OQR94074.1 - 1.5e-21 76.6 0.5 4.6e-21 75.0 0.5 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_2 PF04561.14 OQR94074.1 - 2.7e-16 59.8 0.0 4.6e-16 59.0 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpa2_4 PF06883.12 OQR94074.1 - 1e-09 38.2 0.0 2e-09 37.3 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase I, Rpa2 specific domain DUF2688 PF10892.8 OQR94074.1 - 0.32 10.5 2.6 0.4 10.2 1.4 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2688) ZapB PF06005.12 OQR94075.1 - 0.0023 18.3 3.0 0.0023 18.3 3.0 6.1 3 1 2 5 5 5 3 Cell division protein ZapB DUF4083 PF13314.6 OQR94089.1 - 0.03 14.3 0.6 0.086 12.8 0.6 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4083) RCC1 PF00415.18 OQR94090.1 - 2.3e-99 325.9 14.3 1.1e-16 61.1 0.0 7.2 7 0 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 OQR94090.1 - 1.3e-57 190.5 26.3 3.5e-10 39.4 0.1 8.3 8 0 0 8 8 8 8 Regulator of chromosome condensation (RCC1) repeat BTB PF00651.31 OQR94090.1 - 1.3e-17 64.0 4.5 3.6e-17 62.6 0.2 2.9 2 1 1 3 3 3 1 BTB/POZ domain BACK PF07707.15 OQR94090.1 - 0.0016 18.5 0.2 0.016 15.3 0.0 2.2 1 1 1 2 2 2 1 BTB And C-terminal Kelch Peptidase_C25_C PF03785.14 OQR94090.1 - 0.022 14.6 0.5 29 4.6 0.1 4.2 5 0 0 5 5 5 0 Peptidase family C25, C terminal ig-like domain RHS_repeat PF05593.14 OQR94090.1 - 0.066 13.7 1.9 2.8 8.5 0.2 2.9 3 0 0 3 3 3 0 RHS Repeat WD40 PF00400.32 OQR94091.1 - 1.8e-13 50.7 10.8 0.013 16.3 0.2 6.2 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OQR94091.1 - 9.7e-09 35.4 0.0 0.0071 16.6 0.0 4.8 3 2 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 OQR94091.1 - 0.00038 19.5 0.4 0.25 10.2 0.0 3.3 2 1 1 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein SWIB PF02201.18 OQR94092.1 - 5.2e-16 58.3 0.9 5.2e-16 58.3 0.9 2.2 3 0 0 3 3 3 1 SWIB/MDM2 domain Methyltransf_PK PF05891.12 OQR94092.1 - 0.12 11.8 0.1 0.2 11.2 0.1 1.3 1 0 0 1 1 1 0 AdoMet dependent proline di-methyltransferase Methyltransf_11 PF08241.12 OQR94093.1 - 2.9e-06 27.9 0.0 5.4e-06 27.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OQR94093.1 - 1.1e-05 26.0 0.0 2.2e-05 25.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 OQR94093.1 - 0.0025 17.4 0.0 0.35 10.4 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase small domain Methyltransf_23 PF13489.6 OQR94093.1 - 0.0054 16.6 0.0 0.015 15.1 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OQR94093.1 - 0.046 14.5 0.0 0.39 11.5 0.0 2.2 1 1 0 1 1 1 0 Methyltransferase domain DREV PF05219.12 OQR94093.1 - 0.11 11.6 0.0 0.13 11.3 0.0 1.3 1 0 0 1 1 1 0 DREV methyltransferase 2-oxoacid_dh PF00198.23 OQR94094.1 - 3.7e-82 275.3 0.1 4.7e-82 274.9 0.1 1.1 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) E3_binding PF02817.17 OQR94094.1 - 1.8e-09 37.8 0.1 5.7e-09 36.2 0.0 1.9 2 0 0 2 2 2 1 e3 binding domain DUF2339 PF10101.9 OQR94095.1 - 0.0001 21.1 11.1 0.00016 20.4 11.1 1.4 1 1 0 1 1 1 1 Predicted membrane protein (DUF2339) DUF4293 PF14126.6 OQR94095.1 - 0.028 14.7 17.2 0.25 11.6 0.8 3.3 2 1 1 3 3 3 0 Domain of unknown function (DUF4293) DUF2391 PF09622.10 OQR94095.1 - 0.44 9.8 7.2 0.31 10.3 4.1 2.3 3 0 0 3 3 3 0 Putative integral membrane protein (DUF2391) E1-E2_ATPase PF00122.20 OQR94095.1 - 0.45 10.0 3.4 9 5.8 0.1 2.5 2 1 0 2 2 2 0 E1-E2 ATPase DHHC PF01529.20 OQR94095.1 - 1.8 8.6 23.6 1.7 8.8 4.4 4.0 2 1 2 4 4 4 0 DHHC palmitoyltransferase PX PF00787.24 OQR94106.1 - 0.0015 18.5 0.0 0.0029 17.6 0.0 1.5 1 0 0 1 1 1 1 PX domain NEMP PF10225.9 OQR94107.1 - 0.073 12.7 0.3 0.073 12.7 0.3 1.6 2 0 0 2 2 2 0 NEMP family LRR_8 PF13855.6 OQR94108.1 - 5.8e-05 22.8 10.0 0.0034 17.1 2.4 4.9 4 1 2 6 6 6 3 Leucine rich repeat LRR_4 PF12799.7 OQR94108.1 - 7.9e-05 22.9 20.7 0.58 10.7 0.9 7.1 5 1 2 7 7 7 4 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 OQR94108.1 - 9.2e-05 22.2 7.8 1.2 9.4 0.0 6.1 6 0 0 6 6 6 2 Leucine Rich repeat LRR_1 PF00560.33 OQR94108.1 - 0.094 13.3 12.7 12 6.9 0.0 6.8 8 0 0 8 8 8 0 Leucine Rich Repeat RCR PF12273.8 OQR94110.1 - 3.7e-05 24.4 3.3 0.25 12.0 0.0 3.2 2 0 0 2 2 2 2 Chitin synthesis regulation, resistance to Congo red DUF2157 PF09925.9 OQR94110.1 - 0.00012 21.9 4.7 0.063 13.1 0.0 3.6 4 0 0 4 4 3 2 Predicted membrane protein (DUF2157) CCSMST1 PF15013.6 OQR94110.1 - 0.00035 20.7 0.3 0.19 11.9 0.0 2.7 3 0 0 3 3 2 1 CCSMST1 family Pox_EPC_I2-L1 PF12575.8 OQR94110.1 - 0.0017 18.6 0.1 0.62 10.3 0.0 2.8 2 0 0 2 2 2 1 Poxvirus entry protein complex L1 and I2 DUF3300 PF11737.8 OQR94110.1 - 0.0018 17.9 2.3 0.0089 15.6 0.7 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF3300) 7TM_GPCR_Str PF10326.9 OQR94110.1 - 0.002 17.5 0.3 1.1 8.5 0.0 2.5 3 0 0 3 3 3 2 Serpentine type 7TM GPCR chemoreceptor Str TCRP1 PF14944.6 OQR94110.1 - 0.0023 18.0 5.1 0.0023 18.0 5.1 2.6 2 0 0 2 2 2 1 Tongue Cancer Chemotherapy Resistant Protein 1 DUF3899 PF13038.6 OQR94110.1 - 0.0033 17.9 1.5 0.79 10.3 0.1 2.6 2 0 0 2 2 2 1 Domain of unknown function (DUF3899) MIG-14_Wnt-bd PF06664.12 OQR94110.1 - 0.0035 16.6 0.4 2.3 7.4 0.0 2.5 3 0 0 3 3 3 2 Wnt-binding factor required for Wnt secretion DUF2076 PF09849.9 OQR94110.1 - 0.005 16.9 20.1 0.017 15.2 10.0 2.2 2 0 0 2 2 2 2 Uncharacterized protein conserved in bacteria (DUF2076) DUF4131 PF13567.6 OQR94110.1 - 0.0059 16.3 3.1 2.9 7.5 0.0 3.9 4 0 0 4 4 4 1 Domain of unknown function (DUF4131) DAG1 PF05454.11 OQR94110.1 - 0.021 14.2 0.1 2 7.7 0.0 2.1 2 0 0 2 2 2 0 Dystroglycan (Dystrophin-associated glycoprotein 1) Prominin PF05478.11 OQR94110.1 - 0.025 12.6 0.3 1.5 6.7 0.0 2.1 2 0 0 2 2 2 0 Prominin PXPV PF12778.7 OQR94110.1 - 0.029 14.2 6.5 0.029 14.2 6.5 4.3 2 1 1 3 3 2 0 PXPV repeat (3 copies) DUF3784 PF12650.7 OQR94110.1 - 0.034 14.3 0.3 4.4 7.6 0.0 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF3784) SARAF PF06682.12 OQR94110.1 - 0.037 13.7 6.8 0.1 12.3 0.2 2.9 2 1 0 2 2 2 0 SOCE-associated regulatory factor of calcium homoeostasis DUF2207 PF09972.9 OQR94110.1 - 0.041 12.7 0.0 4.4 6.0 0.0 2.1 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) FtsH_ext PF06480.15 OQR94110.1 - 0.051 13.9 0.4 9.9 6.6 0.1 2.7 2 0 0 2 2 2 0 FtsH Extracellular MFS_Mycoplasma PF07672.13 OQR94110.1 - 0.053 12.8 0.1 10 5.3 0.0 2.3 2 0 0 2 2 2 0 Mycoplasma MFS transporter CD34_antigen PF06365.12 OQR94110.1 - 0.054 13.1 0.0 0.84 9.2 0.0 2.1 2 0 0 2 2 2 0 CD34/Podocalyxin family DUF3098 PF11297.8 OQR94110.1 - 0.062 12.9 0.7 14 5.4 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3098) Trp_oprn_chp PF09534.10 OQR94110.1 - 0.062 13.1 0.5 7.5 6.3 0.0 3.1 3 0 0 3 3 3 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) DUF3522 PF12036.8 OQR94110.1 - 0.065 13.5 1.8 3.1 8.0 1.0 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF3522) TMEM251 PF15190.6 OQR94110.1 - 0.075 13.0 3.9 5.5 7.0 0.0 2.8 3 0 0 3 3 3 0 Transmembrane protein 251 SCIMP PF15050.6 OQR94110.1 - 0.11 13.0 0.8 1.6 9.2 0.0 2.3 2 0 0 2 2 2 0 SCIMP protein DUF3357 PF11837.8 OQR94110.1 - 0.13 12.7 0.0 9.9 6.7 0.0 2.8 3 0 0 3 3 2 0 Domain of unknown function (DUF3357) Saf_2TM PF18303.1 OQR94110.1 - 0.16 11.6 0.4 8.7 5.9 0.1 2.2 2 0 0 2 2 2 0 SAVED-fused 2TM effector domain BatD PF13584.6 OQR94110.1 - 0.16 10.7 0.0 8.3 5.1 0.0 2.2 2 0 0 2 2 2 0 Oxygen tolerance DUF3040 PF11239.8 OQR94110.1 - 0.16 12.2 1.1 17 5.8 0.0 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3040) NupH_GANP PF16768.5 OQR94110.1 - 0.17 11.5 0.7 0.33 10.6 0.7 1.4 1 0 0 1 1 1 0 Nucleoporin homology of Germinal-centre associated nuclear protein DotU PF09850.9 OQR94110.1 - 0.29 10.8 0.8 7.6 6.2 0.0 2.3 2 0 0 2 2 2 0 Type VI secretion system protein DotU Corona_S2 PF01601.16 OQR94110.1 - 0.47 8.9 5.7 2.5 6.5 0.2 2.4 2 0 0 2 2 2 0 Coronavirus S2 glycoprotein SfLAP PF11139.8 OQR94110.1 - 0.66 9.4 8.3 20 4.5 0.0 3.5 4 0 0 4 4 3 0 Sap, sulfolipid-1-addressing protein Stealth_CR2 PF11380.8 OQR94111.1 - 4.7e-25 87.9 0.1 1.1e-24 86.7 0.1 1.6 1 0 0 1 1 1 1 Stealth protein CR2, conserved region 2 Stealth_CR1 PF17101.5 OQR94111.1 - 1.1e-06 28.3 0.4 2.3e-06 27.2 0.4 1.6 1 0 0 1 1 1 1 Stealth protein CR1, conserved region 1 DPM3 PF08285.11 OQR94112.1 - 0.0094 16.1 2.2 0.01 16.0 1.7 1.3 1 1 0 1 1 1 1 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) Phage_holin_3_6 PF07332.11 OQR94112.1 - 0.023 14.7 0.2 0.028 14.5 0.2 1.1 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III DUF998 PF06197.13 OQR94112.1 - 0.032 13.8 1.5 0.046 13.3 1.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF998) Peptidase_U4 PF03419.13 OQR94112.1 - 0.088 12.1 0.2 0.1 11.9 0.2 1.0 1 0 0 1 1 1 0 Sporulation factor SpoIIGA Mannosyl_trans3 PF11051.8 OQR94122.1 - 8.7e-34 117.1 0.0 1.3e-33 116.6 0.0 1.2 1 0 0 1 1 1 1 Mannosyltransferase putative Josephin PF02099.17 OQR94122.1 - 3.1e-19 69.7 0.0 1.6e-18 67.4 0.0 1.8 1 1 1 2 2 2 1 Josephin CholecysA-Rec_N PF09193.10 OQR94122.1 - 0.14 12.2 0.2 0.39 10.8 0.2 1.7 1 0 0 1 1 1 0 Cholecystokinin A receptor, N-terminal GyrI-like PF06445.15 OQR94123.1 - 8.5e-14 52.1 0.0 1.6e-13 51.2 0.0 1.5 1 1 0 1 1 1 1 GyrI-like small molecule binding domain Cass2 PF14526.6 OQR94123.1 - 1.1e-10 41.9 0.0 1.2e-10 41.7 0.0 1.0 1 0 0 1 1 1 1 Integron-associated effector binding protein Arginase PF00491.21 OQR94124.1 - 1.4e-67 228.1 0.0 1.8e-67 227.8 0.0 1.1 1 0 0 1 1 1 1 Arginase family HA2 PF04408.23 OQR94125.1 - 6.6e-21 74.6 0.0 1.6e-20 73.4 0.0 1.6 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 OQR94125.1 - 5.9e-15 55.4 0.0 1.7e-14 53.9 0.0 1.8 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 OQR94125.1 - 6.2e-12 45.8 0.0 1.4e-11 44.7 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 OQR94125.1 - 3.4e-07 30.2 0.0 8.1e-07 29.0 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_19 PF13245.6 OQR94125.1 - 4.1e-05 24.0 0.0 7.8e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 OQR94125.1 - 0.00021 21.6 0.0 0.00044 20.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 OQR94125.1 - 0.01 14.9 0.1 0.026 13.6 0.0 1.6 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_30 PF13604.6 OQR94125.1 - 0.015 15.1 0.0 0.032 13.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain Flavi_DEAD PF07652.14 OQR94125.1 - 0.032 14.2 0.1 0.056 13.4 0.1 1.4 1 0 0 1 1 1 0 Flavivirus DEAD domain ATPase PF06745.13 OQR94125.1 - 0.037 13.4 0.0 0.073 12.4 0.0 1.4 1 0 0 1 1 1 0 KaiC DUF2075 PF09848.9 OQR94125.1 - 0.052 12.8 0.0 0.073 12.3 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) PhoH PF02562.16 OQR94125.1 - 0.084 12.3 0.1 0.24 10.8 0.1 1.7 2 0 0 2 2 2 0 PhoH-like protein ResIII PF04851.15 OQR94125.1 - 0.091 12.8 0.2 0.74 9.8 0.1 2.4 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit UvrD-helicase PF00580.21 OQR94125.1 - 0.15 11.5 0.3 0.54 9.7 0.3 1.7 1 1 1 2 2 2 0 UvrD/REP helicase N-terminal domain AAA_33 PF13671.6 OQR94125.1 - 0.17 12.0 0.0 0.33 11.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain eIF2A PF08662.11 OQR94137.1 - 5.2e-71 238.6 0.0 5e-68 228.8 0.0 3.3 3 1 0 4 4 4 2 Eukaryotic translation initiation factor eIF2A PD40 PF07676.12 OQR94137.1 - 0.57 10.2 2.8 15 5.7 0.0 4.1 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat Peptidase_M8 PF01457.16 OQR94138.1 - 1.2e-121 407.1 46.2 1.6e-62 211.9 15.1 5.4 2 2 1 4 4 4 3 Leishmanolysin Astacin PF01400.24 OQR94138.1 - 0.0065 16.1 0.4 4.6 6.8 0.0 3.0 3 0 0 3 3 3 2 Astacin (Peptidase family M12A) TPR_18 PF13512.6 OQR94138.1 - 0.0075 16.4 0.0 0.15 12.2 0.0 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat cEGF PF12662.7 OQR94138.1 - 0.18 11.8 18.7 0.16 11.9 3.3 3.8 3 0 0 3 3 3 0 Complement Clr-like EGF-like Peptidase_M10 PF00413.24 OQR94138.1 - 0.23 11.3 0.0 17 5.2 0.0 2.2 2 0 0 2 2 2 0 Matrixin PX PF00787.24 OQR94139.1 - 1.4e-05 25.0 0.1 3.4e-05 23.8 0.1 1.6 1 1 0 1 1 1 1 PX domain DUF5344 PF17279.2 OQR94139.1 - 0.017 15.7 0.2 0.049 14.2 0.2 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5344) DCB PF16213.5 OQR94140.1 - 3.9e-32 111.4 6.7 8.5e-31 107.0 2.8 4.0 3 0 0 3 3 3 1 Dimerisation and cyclophilin-binding domain of Mon2 Mon2_C PF16206.5 OQR94140.1 - 1.5e-24 86.3 2.4 2.3e-22 79.0 0.3 3.2 3 1 0 3 3 3 1 C-terminal region of Mon2 protein Sec7_N PF12783.7 OQR94140.1 - 4.7e-16 59.1 0.7 4.7e-16 59.1 0.7 3.9 4 1 0 4 4 4 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.10 OQR94140.1 - 0.015 15.1 8.3 0.14 12.0 0.0 5.1 4 1 0 4 4 4 0 Domain of unknown function (DUF1981) Atx10homo_assoc PF09759.9 OQR94141.1 - 0.0013 18.8 1.4 0.0032 17.4 0.4 2.0 1 1 1 2 2 2 2 Spinocerebellar ataxia type 10 protein domain DUF3361 PF11841.8 OQR94141.1 - 0.098 12.6 1.7 2.8 7.9 0.2 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF3361) UPF0220 PF05255.11 OQR94142.1 - 0.061 12.9 2.3 0.088 12.3 0.4 2.1 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0220) FAD_binding_1 PF00667.20 OQR94143.1 - 3.4e-59 200.1 0.1 5.8e-59 199.4 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 OQR94143.1 - 7.1e-32 110.6 0.5 1.4e-31 109.6 0.5 1.5 1 0 0 1 1 1 1 Flavodoxin POPLD PF08170.12 OQR94143.1 - 1.1e-18 67.3 1.3 5.7e-18 65.0 0.0 2.7 3 0 0 3 3 3 1 POPLD (NUC188) domain NAD_binding_1 PF00175.21 OQR94143.1 - 2.6e-17 63.4 0.1 9.7e-17 61.6 0.1 2.1 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain POP1 PF06978.11 OQR94143.1 - 2.7e-10 40.6 5.4 2.5e-06 27.6 0.1 2.7 1 1 1 2 2 2 2 Ribonucleases P/MRP protein subunit POP1 Flavodoxin_5 PF12724.7 OQR94143.1 - 0.0033 17.7 0.0 0.019 15.2 0.0 2.4 2 1 0 2 2 2 1 Flavodoxin domain Aa_trans PF01490.18 OQR94145.1 - 1.1e-37 129.7 18.3 1.4e-37 129.4 18.3 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Ribosomal_L41 PF05162.13 OQR94195.1 - 5.4e-08 32.8 33.2 7e-08 32.4 33.2 1.2 1 0 0 1 1 1 1 Ribosomal protein L41 ubiquitin PF00240.23 OQR94195.1 - 1.9e-05 24.3 0.0 2.8e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 OQR94195.1 - 0.035 13.9 0.0 0.055 13.3 0.0 1.3 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Ank_2 PF12796.7 OQR94196.1 - 1.3e-36 125.0 5.9 2.6e-16 60.0 0.8 4.4 2 2 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OQR94196.1 - 4e-30 103.5 10.8 2.6e-09 37.2 0.4 6.7 5 2 2 7 7 7 5 Ankyrin repeats (many copies) Ank_4 PF13637.6 OQR94196.1 - 6.6e-30 103.1 9.5 9.5e-09 35.6 0.2 5.2 4 2 2 6 6 6 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQR94196.1 - 1.9e-24 83.1 13.2 9.1e-05 22.6 0.1 7.8 8 0 0 8 8 8 6 Ankyrin repeat Ank PF00023.30 OQR94196.1 - 4e-19 68.1 17.3 1.5e-05 25.2 0.1 6.4 5 1 1 6 6 6 4 Ankyrin repeat FAM183 PF14886.6 OQR94197.1 - 8.8e-13 48.9 0.4 1.3e-12 48.4 0.4 1.2 1 0 0 1 1 1 1 FAM183A and FAM183B related DUF3011 PF11218.8 OQR94197.1 - 0.014 15.4 0.1 0.021 14.8 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3011) LLC1 PF14945.6 OQR94197.1 - 0.015 15.9 0.6 0.026 15.1 0.6 1.4 1 1 0 1 1 1 0 Normal lung function maintenance, Low in Lung Cancer 1 protein LRR_6 PF13516.6 OQR94198.1 - 1.4e-13 49.7 9.6 0.00019 21.2 0.1 6.3 6 0 0 6 6 6 3 Leucine Rich repeat LRR_8 PF13855.6 OQR94198.1 - 1.6e-06 27.8 2.3 0.00012 21.8 0.1 3.0 2 0 0 2 2 2 1 Leucine rich repeat LRR_1 PF00560.33 OQR94198.1 - 2.4e-05 24.2 1.7 6.7 7.7 0.0 5.6 4 1 1 5 5 5 1 Leucine Rich Repeat LRR_4 PF12799.7 OQR94198.1 - 2.7e-05 24.4 5.5 0.038 14.4 0.1 4.8 3 2 2 5 5 5 2 Leucine Rich repeats (2 copies) Glyco_hydro_17 PF00332.18 OQR94198.1 - 0.068 12.8 3.0 0.24 11.0 3.0 1.9 1 0 0 1 1 1 0 Glycosyl hydrolases family 17 HrpB7 PF09486.10 OQR94198.1 - 0.38 11.1 5.7 5.9 7.3 0.2 2.3 2 0 0 2 2 2 0 Bacterial type III secretion protein (HrpB7) DUF16 PF01519.16 OQR94198.1 - 0.42 11.1 4.0 1 9.9 0.4 2.4 1 1 1 2 2 2 0 Protein of unknown function DUF16 PspA_IM30 PF04012.12 OQR94198.1 - 0.73 9.4 4.2 3.3 7.2 3.7 1.9 1 1 0 1 1 1 0 PspA/IM30 family Rootletin PF15035.6 OQR94198.1 - 0.74 9.8 4.6 1.3 9.0 4.6 1.3 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion SlyX PF04102.12 OQR94198.1 - 2.5 8.8 4.6 13 6.5 0.3 2.7 2 0 0 2 2 2 0 SlyX Jnk-SapK_ap_N PF09744.9 OQR94198.1 - 4.3 7.6 5.8 34 4.6 2.3 2.5 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 DDE_Tnp_4 PF13359.6 OQR94201.1 - 2.4e-07 30.6 0.0 4.5e-07 29.7 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease TPR_2 PF07719.17 OQR94202.1 - 4.4e-08 32.6 5.2 0.0088 16.1 0.2 4.7 4 0 0 4 4 4 2 Tetratricopeptide repeat F-box-like PF12937.7 OQR94202.1 - 3.5e-07 30.0 0.5 3.5e-07 30.0 0.5 2.4 2 0 0 2 2 2 1 F-box-like TPR_1 PF00515.28 OQR94202.1 - 8.2e-06 25.4 3.9 0.24 11.3 0.1 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 OQR94202.1 - 0.00046 20.4 6.1 0.0028 17.9 0.1 4.1 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_8 PF13181.6 OQR94202.1 - 0.00082 19.4 5.4 0.072 13.3 0.0 4.4 5 1 1 6 6 6 1 Tetratricopeptide repeat TPR_17 PF13431.6 OQR94202.1 - 0.0016 18.7 4.5 4.9 7.8 0.2 4.5 4 0 0 4 4 4 1 Tetratricopeptide repeat F-box PF00646.33 OQR94202.1 - 0.0032 17.3 1.3 0.01 15.7 0.0 2.4 2 0 0 2 2 2 1 F-box domain TPR_14 PF13428.6 OQR94202.1 - 0.013 16.3 3.3 0.6 11.1 0.1 3.5 2 1 1 3 3 3 0 Tetratricopeptide repeat DUF4192 PF13830.6 OQR94202.1 - 0.023 14.8 0.1 0.067 13.2 0.1 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4192) TPR_19 PF14559.6 OQR94202.1 - 0.044 14.3 2.5 1 9.9 1.5 3.2 2 1 0 2 2 2 0 Tetratricopeptide repeat ANAPC3 PF12895.7 OQR94202.1 - 3.9 7.8 7.2 6.2 7.1 0.1 3.1 3 1 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 PHTB1_N PF14727.6 OQR94210.1 - 1.4e-130 436.4 0.0 1.8e-130 436.1 0.0 1.1 1 0 0 1 1 1 1 PTHB1 N-terminus PHTB1_C PF14728.6 OQR94210.1 - 2.2e-128 428.6 0.2 2.7e-128 428.2 0.2 1.1 1 0 0 1 1 1 1 PTHB1 C-terminus ORC4_C PF14629.6 OQR94218.1 - 3.9e-18 65.6 0.5 8.7e-18 64.5 0.5 1.6 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 4 C-terminus HHH_8 PF14716.6 OQR94218.1 - 5.6e-15 55.5 1.0 1.4e-14 54.2 1.0 1.8 1 0 0 1 1 1 1 Helix-hairpin-helix domain AAA_16 PF13191.6 OQR94218.1 - 1.4e-07 32.0 0.8 1.2e-06 29.0 0.8 2.6 1 1 0 1 1 1 1 AAA ATPase domain DUF815 PF05673.13 OQR94218.1 - 0.00017 20.8 5.5 0.00045 19.4 0.2 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA PF00004.29 OQR94218.1 - 0.0002 21.8 0.0 0.00082 19.8 0.0 2.1 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 OQR94218.1 - 0.00024 21.1 1.1 0.0011 18.9 0.1 2.4 2 0 0 2 2 2 1 NACHT domain AAA_22 PF13401.6 OQR94218.1 - 0.00025 21.3 0.1 0.0012 19.1 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 OQR94218.1 - 0.027 14.0 0.0 0.13 11.7 0.0 2.2 1 0 0 1 1 1 0 P-loop containing dynein motor region DHHC PF01529.20 OQR94220.1 - 1.6e-28 99.5 19.6 9.8e-27 93.7 15.2 2.8 1 1 1 2 2 2 1 DHHC palmitoyltransferase zinc_ribbon_15 PF17032.5 OQR94220.1 - 0.0053 17.5 0.6 0.0053 17.5 0.6 1.7 2 0 0 2 2 2 1 zinc-ribbon family DZR PF12773.7 OQR94220.1 - 0.75 9.9 8.4 1.5 8.9 8.4 1.5 1 0 0 1 1 1 0 Double zinc ribbon Ank_2 PF12796.7 OQR94221.1 - 3.9e-25 88.3 16.3 5.2e-07 30.2 0.6 3.0 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQR94221.1 - 1e-15 57.8 7.4 1.8e-06 28.4 0.2 4.6 3 1 1 5 5 5 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQR94221.1 - 2e-10 40.0 7.2 1.6 9.5 0.1 6.3 3 2 3 6 6 6 4 Ankyrin repeat Ank_5 PF13857.6 OQR94221.1 - 6.6e-10 39.1 6.8 0.1 12.9 0.0 5.7 1 1 5 6 6 6 4 Ankyrin repeats (many copies) DUF249 PF03158.13 OQR94221.1 - 0.028 14.1 0.1 6.6 6.4 0.0 2.3 2 0 0 2 2 2 0 Multigene family 530 protein DUF5049 PF16468.5 OQR94221.1 - 0.05 13.5 0.0 1.1 9.3 0.0 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF5049) Ank PF00023.30 OQR94221.1 - 0.066 13.7 8.0 49 4.6 1.8 5.0 3 2 1 4 4 4 0 Ankyrin repeat Pterin_bind PF00809.22 OQR94222.1 - 1.5e-78 263.9 0.1 1.9e-78 263.5 0.1 1.1 1 0 0 1 1 1 1 Pterin binding enzyme HPPK PF01288.20 OQR94222.1 - 1.9e-35 121.7 0.0 3.9e-35 120.8 0.0 1.5 1 0 0 1 1 1 1 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) MIF4G_like PF09088.11 OQR94222.1 - 0.16 11.7 0.0 0.37 10.5 0.0 1.5 1 0 0 1 1 1 0 MIF4G like SR-25 PF10500.9 OQR94223.1 - 0.87 9.1 5.8 1.3 8.6 5.8 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein TPR_14 PF13428.6 OQR94230.1 - 0.0029 18.3 1.9 0.8 10.7 0.1 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat Pro_isomerase PF00160.21 OQR94231.1 - 4.3e-45 153.8 0.0 4.9e-45 153.6 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Abhydrolase_1 PF00561.20 OQR94232.1 - 4.3e-29 101.9 0.0 5.7e-29 101.5 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 OQR94232.1 - 3.9e-05 24.4 0.1 5.4e-05 23.9 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 OQR94232.1 - 0.0016 17.8 0.1 0.0096 15.2 0.1 2.0 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Esterase PF00756.20 OQR94232.1 - 0.0027 17.4 0.0 0.0035 17.0 0.0 1.2 1 0 0 1 1 1 1 Putative esterase Peptidase_S9 PF00326.21 OQR94232.1 - 0.15 11.5 0.0 4.6 6.6 0.0 2.2 2 0 0 2 2 2 0 Prolyl oligopeptidase family PHD PF00628.29 OQR94234.1 - 6.7e-06 25.9 9.4 3.2e-05 23.7 9.4 2.3 1 0 0 1 1 1 1 PHD-finger Transket_pyr PF02779.24 OQR94235.1 - 3e-48 163.8 0.0 4e-48 163.4 0.0 1.2 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 OQR94235.1 - 3.3e-35 120.7 0.0 6.2e-35 119.8 0.0 1.4 1 0 0 1 1 1 1 Transketolase, C-terminal domain PFOR_II PF17147.4 OQR94235.1 - 0.016 15.5 0.0 0.029 14.7 0.0 1.4 1 0 0 1 1 1 0 Pyruvate:ferredoxin oxidoreductase core domain II DENN PF02141.21 OQR94236.1 - 1.8e-29 103.1 2.5 6.5e-27 94.7 0.3 2.4 2 0 0 2 2 2 2 DENN (AEX-3) domain uDENN PF03456.18 OQR94236.1 - 5.3e-08 33.5 0.3 2.4e-07 31.4 0.3 2.3 1 0 0 1 1 1 1 uDENN domain dDENN PF03455.19 OQR94236.1 - 0.0049 16.8 0.6 0.015 15.3 0.6 1.8 1 0 0 1 1 1 1 dDENN domain PDZ_6 PF17820.1 OQR94236.1 - 0.066 13.1 0.0 0.17 11.8 0.0 1.6 1 0 0 1 1 1 0 PDZ domain BK_channel_a PF03493.18 OQR94237.1 - 2.1e-17 63.1 0.0 6.9e-16 58.2 0.0 2.6 2 0 0 2 2 2 1 Calcium-activated BK potassium channel alpha subunit Ion_trans PF00520.31 OQR94237.1 - 4e-12 45.9 19.5 9.4e-12 44.7 19.5 1.5 1 1 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 OQR94237.1 - 3.2e-10 39.8 4.6 1.1e-09 38.2 4.6 1.9 1 0 0 1 1 1 1 Ion channel DUF3080 PF11279.8 OQR94238.1 - 0.017 14.4 0.6 0.017 14.4 0.6 2.2 2 1 1 3 3 3 0 Protein of unknown function (DUF3080) PHD PF00628.29 OQR94238.1 - 0.024 14.5 11.3 0.22 11.5 11.3 2.3 1 1 0 1 1 1 0 PHD-finger GFO_IDH_MocA PF01408.22 OQR94239.1 - 1.1e-18 68.2 0.1 1.3e-18 68.0 0.1 1.1 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Trp_syntA PF00290.20 OQR94240.1 - 2.2e-81 272.5 0.3 2.9e-81 272.1 0.3 1.1 1 0 0 1 1 1 1 Tryptophan synthase alpha chain Tfb4 PF03850.14 OQR94240.1 - 2.2e-56 191.4 4.9 3.3e-56 190.8 4.9 1.3 1 0 0 1 1 1 1 Transcription factor Tfb4 His_biosynth PF00977.21 OQR94240.1 - 0.07 12.6 0.0 0.38 10.2 0.0 2.0 2 0 0 2 2 2 0 Histidine biosynthesis protein TPR_1 PF00515.28 OQR94241.1 - 1.7e-11 43.4 0.4 0.00095 18.9 0.0 3.7 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.6 OQR94241.1 - 9.3e-07 28.6 0.5 0.00051 20.1 0.0 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.6 OQR94241.1 - 9.3e-07 28.9 0.1 2.8e-06 27.4 0.0 1.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.17 OQR94241.1 - 1e-06 28.4 0.1 0.084 13.0 0.0 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 OQR94241.1 - 1.1e-06 29.1 1.4 0.00057 20.3 0.1 3.0 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.6 OQR94241.1 - 7.1e-06 25.6 0.6 0.023 14.4 0.2 2.9 2 1 1 3 3 3 2 TPR repeat TPR_6 PF13174.6 OQR94241.1 - 1.2e-05 25.6 0.4 0.011 16.3 0.1 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.6 OQR94241.1 - 2.8e-05 24.7 0.2 0.046 14.4 0.1 2.7 3 0 0 3 3 2 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 OQR94241.1 - 0.00072 19.6 0.4 0.011 15.8 0.0 2.9 2 1 1 3 3 3 1 Fis1 C-terminal tetratricopeptide repeat TPR_14 PF13428.6 OQR94241.1 - 0.0023 18.6 0.2 1.2 10.1 0.1 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.6 OQR94241.1 - 0.0051 17.1 0.1 0.44 11.0 0.0 3.2 3 1 0 3 3 3 1 Tetratricopeptide repeat GDC-P PF02347.16 OQR94242.1 - 1.9e-194 646.5 0.0 1.8e-176 587.2 0.0 3.1 3 0 0 3 3 3 3 Glycine cleavage system P-protein Aminotran_5 PF00266.19 OQR94242.1 - 3.4e-09 36.1 0.0 2.4e-07 30.1 0.1 2.2 2 0 0 2 2 2 2 Aminotransferase class-V Beta_elim_lyase PF01212.21 OQR94242.1 - 0.00024 20.5 0.1 0.00048 19.5 0.1 1.4 1 0 0 1 1 1 1 Beta-eliminating lyase Sulf_transp PF04143.14 OQR94303.1 - 4.7e-31 108.5 31.9 1.5e-30 106.9 31.9 1.7 1 1 0 1 1 1 1 Sulphur transport Myb_DNA-bind_3 PF12776.7 OQR94303.1 - 7.6e-13 49.3 0.1 3.4e-12 47.2 0.1 2.2 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain DUF573 PF04504.14 OQR94303.1 - 4.1 8.1 6.3 1.3 9.7 0.1 2.9 3 0 0 3 3 3 0 Protein of unknown function, DUF573 RRP36 PF06102.12 OQR94304.1 - 0.036 14.0 5.0 0.06 13.3 5.0 1.3 1 0 0 1 1 1 0 rRNA biogenesis protein RRP36 UPF0122 PF04297.14 OQR94304.1 - 0.17 12.1 2.7 14 5.9 0.0 2.7 1 1 1 2 2 2 0 Putative helix-turn-helix protein, YlxM / p13 like Transglut_core PF01841.19 OQR94305.1 - 1e-12 48.5 0.3 1.9e-12 47.6 0.3 1.4 1 0 0 1 1 1 1 Transglutaminase-like superfamily PUB PF09409.10 OQR94305.1 - 3.1e-09 36.6 0.1 9.5e-09 35.1 0.1 1.8 1 0 0 1 1 1 1 PUB domain Rad4 PF03835.15 OQR94305.1 - 4.2e-08 33.0 0.7 1e-07 31.7 0.7 1.6 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain AZUL PF16558.5 OQR94305.1 - 5.2e-05 23.4 0.6 0.00023 21.3 0.6 2.2 1 0 0 1 1 1 1 Amino-terminal Zinc-binding domain of ubiquitin ligase E3A PAW PF04721.17 OQR94305.1 - 0.031 14.1 0.3 0.059 13.1 0.3 1.4 1 0 0 1 1 1 0 PNGase C-terminal domain, mannose-binding module PAW Jacalin PF01419.17 OQR94305.1 - 0.084 12.8 0.0 0.17 11.8 0.0 1.5 1 0 0 1 1 1 0 Jacalin-like lectin domain Sec1 PF00995.23 OQR94306.1 - 7.4e-103 345.7 0.0 9e-103 345.5 0.0 1.0 1 0 0 1 1 1 1 Sec1 family Exo_endo_phos PF03372.23 OQR94307.1 - 2.8e-12 46.7 0.0 5e-12 45.9 0.0 1.4 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family WD40 PF00400.32 OQR94308.1 - 1.3e-17 63.8 3.9 0.0042 17.9 0.0 6.3 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OQR94308.1 - 1e-11 44.9 0.2 0.00013 22.2 0.5 4.4 3 1 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 OQR94308.1 - 9.5e-08 31.1 2.9 1.3e-05 24.1 0.6 2.3 1 1 0 2 2 2 2 Nucleoporin Nup120/160 PALB2_WD40 PF16756.5 OQR94308.1 - 0.018 13.9 0.1 0.094 11.6 0.1 2.0 2 0 0 2 2 2 0 Partner and localizer of BRCA2 WD40 domain Ge1_WD40 PF16529.5 OQR94308.1 - 0.028 13.4 0.6 1.6 7.6 0.1 2.8 2 1 1 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein IQ PF00612.27 OQR94309.1 - 2.1e-10 39.5 71.7 0.023 14.4 0.1 13.0 12 1 1 13 13 13 8 IQ calmodulin-binding motif LRR_6 PF13516.6 OQR94309.1 - 1.9e-06 27.5 22.4 0.1 12.7 0.3 8.9 8 1 1 9 9 9 2 Leucine Rich repeat LRR_4 PF12799.7 OQR94309.1 - 0.00037 20.8 28.4 0.018 15.5 0.9 8.6 4 3 6 10 10 10 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 OQR94309.1 - 0.0078 15.9 7.6 0.015 15.0 1.0 4.6 4 0 0 4 4 4 1 Leucine rich repeat Methyltransf_11 PF08241.12 OQR94312.1 - 2.9e-10 40.7 0.0 4.9e-10 39.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OQR94312.1 - 3.4e-08 33.4 0.0 3.7e-08 33.3 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OQR94312.1 - 3.2e-06 27.7 0.1 1.1e-05 26.0 0.1 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OQR94312.1 - 0.00083 20.1 0.0 0.0011 19.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 OQR94312.1 - 0.052 12.9 0.1 0.098 12.0 0.1 1.4 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family PcrB PF01884.17 OQR94312.1 - 0.13 11.7 0.0 0.15 11.5 0.0 1.0 1 0 0 1 1 1 0 PcrB family DUF455 PF04305.14 OQR94313.1 - 5.9e-76 255.3 0.0 8.5e-76 254.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF455) Glyco_trans_1_4 PF13692.6 OQR94313.1 - 3.5e-18 66.3 0.0 7.9e-18 65.2 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferases group 1 DUF273 PF03314.14 OQR94313.1 - 0.089 12.3 0.2 0.4 10.2 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function, DUF273 YvrJ PF12841.7 OQR94314.1 - 0.026 14.1 0.2 0.096 12.2 0.2 2.1 1 0 0 1 1 1 0 YvrJ protein family Vac_Fusion PF02346.16 OQR94314.1 - 0.95 9.1 3.7 7.4 6.3 0.1 3.4 4 0 0 4 4 4 0 Chordopoxvirus multifunctional envelope protein A27 SlyX PF04102.12 OQR94314.1 - 7.7 7.2 7.4 15 6.3 2.4 3.4 3 0 0 3 3 3 0 SlyX Clathrin_H_link PF13838.6 OQR94315.1 - 0.084 12.8 1.7 0.41 10.6 1.7 2.3 1 0 0 1 1 1 0 Clathrin-H-link Fer4_24 PF18109.1 OQR94315.1 - 1 9.7 5.5 18 5.7 1.2 2.6 2 0 0 2 2 2 0 Ferredoxin I 4Fe-4S cluster domain Syntaxin-6_N PF09177.11 OQR94315.1 - 9.7 6.8 29.5 0.37 11.4 4.4 4.1 3 1 0 3 3 3 0 Syntaxin 6, N-terminal NAD_binding_4 PF07993.12 OQR94316.1 - 2.5e-70 236.6 0.0 3.8e-70 236.0 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein Acyltransferase PF01553.21 OQR94316.1 - 4.5e-23 81.3 0.0 8.8e-23 80.4 0.0 1.5 1 0 0 1 1 1 1 Acyltransferase Sterile PF03015.19 OQR94316.1 - 9.9e-13 48.1 0.2 2.1e-12 47.1 0.2 1.6 1 0 0 1 1 1 1 Male sterility protein GDP_Man_Dehyd PF16363.5 OQR94316.1 - 7e-05 22.4 1.2 0.015 14.7 0.4 3.1 2 1 0 2 2 2 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 OQR94316.1 - 0.00026 20.5 0.0 0.0012 18.4 0.0 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 OQR94316.1 - 0.00083 18.4 0.1 0.012 14.6 0.0 2.4 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 OQR94316.1 - 0.031 13.4 0.0 0.098 11.8 0.0 1.9 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein DUF433 PF04255.14 OQR94316.1 - 0.078 12.8 0.1 3.5 7.6 0.0 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF433) EF-hand_7 PF13499.6 OQR94375.1 - 1.2e-16 60.9 11.4 3.2e-10 40.3 0.4 3.5 4 0 0 4 4 4 2 EF-hand domain pair EF-hand_1 PF00036.32 OQR94375.1 - 3.2e-11 42.0 9.5 6.6e-05 22.2 0.2 4.5 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.6 OQR94375.1 - 5.5e-10 38.4 3.6 0.00016 21.3 0.1 4.7 4 0 0 4 4 4 3 EF-hand domain EF-hand_8 PF13833.6 OQR94375.1 - 7.5e-06 25.7 3.1 1.1 9.2 0.0 4.3 3 1 1 4 4 4 3 EF-hand domain pair EF-hand_5 PF13202.6 OQR94375.1 - 1.4e-05 24.4 3.4 0.00059 19.2 0.3 3.7 3 0 0 3 3 3 1 EF hand IQ PF00612.27 OQR94375.1 - 0.02 14.7 18.9 0.12 12.3 0.7 4.8 5 0 0 5 5 5 0 IQ calmodulin-binding motif SPARC_Ca_bdg PF10591.9 OQR94375.1 - 0.048 14.0 8.8 0.25 11.7 0.1 3.6 3 0 0 3 3 3 0 Secreted protein acidic and rich in cysteine Ca binding region zf-C2H2_4 PF13894.6 OQR94375.1 - 5.3 8.2 6.3 3.6 8.7 2.9 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger DLIC PF05783.11 OQR94376.1 - 9.4e-38 130.2 0.0 3.2e-37 128.5 0.0 1.7 1 1 0 1 1 1 1 Dynein light intermediate chain (DLIC) Roc PF08477.13 OQR94376.1 - 0.00093 19.4 0.0 0.0064 16.7 0.0 2.4 2 1 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase AAA_16 PF13191.6 OQR94376.1 - 0.028 14.8 0.3 0.41 11.0 0.0 2.4 2 1 0 2 2 2 0 AAA ATPase domain AAA_29 PF13555.6 OQR94376.1 - 0.11 12.2 0.0 0.25 11.1 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF2689 PF10894.8 OQR94376.1 - 0.16 11.8 0.1 0.37 10.6 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2689) EF-hand_6 PF13405.6 OQR94377.1 - 7.8e-13 47.2 0.3 0.0053 16.6 0.0 4.5 4 0 0 4 4 4 3 EF-hand domain EF-hand_7 PF13499.6 OQR94377.1 - 6.1e-10 39.4 0.0 0.091 13.2 0.0 3.7 3 1 0 3 3 3 3 EF-hand domain pair EF-hand_1 PF00036.32 OQR94377.1 - 2.7e-09 35.9 0.0 0.0072 15.8 0.0 4.5 4 0 0 4 4 4 2 EF hand EF-hand_9 PF14658.6 OQR94377.1 - 1.7e-08 34.6 0.0 0.029 14.7 0.0 3.5 3 0 0 3 3 3 2 EF-hand domain EF-hand_5 PF13202.6 OQR94377.1 - 0.00016 21.0 0.1 0.02 14.4 0.0 2.8 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.6 OQR94377.1 - 0.00031 20.5 0.0 3.7 7.5 0.0 4.4 4 1 1 5 5 5 2 EF-hand domain pair PgpA PF04608.13 OQR94377.1 - 0.024 14.7 0.0 13 5.8 0.0 2.9 3 0 0 3 3 3 0 Phosphatidylglycerophosphatase A SPARC_Ca_bdg PF10591.9 OQR94377.1 - 0.18 12.1 0.7 10 6.5 0.0 2.9 3 0 0 3 3 3 0 Secreted protein acidic and rich in cysteine Ca binding region RNase_PH PF01138.21 OQR94378.1 - 1.1e-15 58.3 0.0 1.6e-15 57.7 0.0 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 OQR94378.1 - 1.9e-10 40.6 0.1 4.2e-10 39.5 0.1 1.6 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 PH PF00169.29 OQR94379.1 - 1.3e-16 60.9 0.3 2e-16 60.4 0.3 1.3 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 OQR94379.1 - 3.4e-05 24.2 0.8 8.1e-05 23.0 0.8 1.6 1 1 0 1 1 1 1 Pleckstrin homology domain PH_13 PF16652.5 OQR94379.1 - 0.0055 16.5 0.2 0.015 15.1 0.1 1.7 2 0 0 2 2 2 1 Pleckstrin homology domain PH_9 PF15410.6 OQR94379.1 - 0.0072 16.7 0.1 0.064 13.6 0.1 2.1 1 1 0 1 1 1 1 Pleckstrin homology domain PH_3 PF14593.6 OQR94379.1 - 0.025 14.7 0.1 0.098 12.8 0.1 1.8 1 1 0 1 1 1 0 PH domain PH_4 PF15404.6 OQR94379.1 - 0.078 12.8 0.2 0.14 11.9 0.2 1.5 1 1 1 2 2 2 0 Pleckstrin homology domain PH_2 PF08458.10 OQR94379.1 - 0.14 12.6 0.1 0.38 11.1 0.0 1.8 1 1 0 1 1 1 0 Plant pleckstrin homology-like region FYVE PF01363.21 OQR94380.1 - 5.2e-16 58.5 13.2 1.1e-15 57.5 13.2 1.5 1 0 0 1 1 1 1 FYVE zinc finger GAF PF01590.26 OQR94380.1 - 1.4e-06 28.9 0.0 3.3e-06 27.8 0.0 1.6 1 0 0 1 1 1 1 GAF domain Metallophos PF00149.28 OQR94381.1 - 1.8e-13 51.5 1.4 2.9e-13 50.8 1.4 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Pur_ac_phosph_N PF16656.5 OQR94381.1 - 6.3e-08 33.1 0.1 2.1e-07 31.4 0.1 1.9 1 0 0 1 1 1 1 Purple acid Phosphatase, N-terminal domain Metallophos_2 PF12850.7 OQR94381.1 - 0.00079 19.7 0.0 0.52 10.5 0.0 2.3 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase superfamily domain P16-Arc PF04699.14 OQR94382.1 - 0.045 14.2 0.2 9 6.8 0.0 3.0 3 0 0 3 3 3 0 ARP2/3 complex 16 kDa subunit (p16-Arc) DUF1041 PF06292.17 OQR94382.1 - 0.12 12.8 3.7 6.3 7.3 0.0 4.0 4 0 0 4 4 4 0 Domain of Unknown Function (DUF1041) Glyco_hydro_6 PF01341.17 OQR94383.1 - 1.4e-94 317.2 16.6 5e-47 161.1 2.6 3.7 2 2 1 3 3 3 3 Glycosyl hydrolases family 6 Snurportin1 PF11538.8 OQR94383.1 - 0.0084 16.3 3.8 0.0084 16.3 3.8 2.5 3 0 0 3 3 3 1 Snurportin1 Ank_2 PF12796.7 OQR94384.1 - 2.2e-15 57.0 9.8 9e-05 23.0 0.2 5.6 2 2 5 7 7 7 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQR94384.1 - 2.1e-13 50.5 2.9 0.0049 17.4 0.0 7.4 5 2 3 8 8 8 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 OQR94384.1 - 6e-12 45.6 13.9 0.41 11.0 0.3 7.7 4 2 4 8 8 8 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQR94384.1 - 3.4e-06 27.0 7.6 6 7.8 0.0 8.1 8 1 1 9 9 9 1 Ankyrin repeat Ank PF00023.30 OQR94384.1 - 0.0061 17.0 1.0 84 3.9 0.0 5.7 4 2 0 4 4 4 0 Ankyrin repeat TSLP PF15216.6 OQR94384.1 - 0.12 12.6 0.2 0.36 11.1 0.2 1.8 1 1 0 1 1 1 0 Thymic stromal lymphopoietin Aldose_epim PF01263.20 OQR94397.1 - 5e-38 131.1 0.0 5.6e-38 130.9 0.0 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase AKAP7_NLS PF10469.9 OQR94398.1 - 3.3e-20 72.9 0.0 5.3e-20 72.2 0.0 1.3 1 0 0 1 1 1 1 AKAP7 2'5' RNA ligase-like domain AAA_33 PF13671.6 OQR94398.1 - 5.3e-06 26.7 3.2 5.4e-06 26.6 0.0 2.4 2 1 0 2 2 2 1 AAA domain 2_5_RNA_ligase2 PF13563.6 OQR94398.1 - 6e-06 26.2 0.0 1e-05 25.5 0.0 1.3 1 0 0 1 1 1 1 2'-5' RNA ligase superfamily AAA_16 PF13191.6 OQR94398.1 - 0.00016 22.1 0.0 0.0031 17.9 0.0 2.7 3 0 0 3 3 3 1 AAA ATPase domain KTI12 PF08433.10 OQR94398.1 - 0.00028 20.4 0.0 0.00044 19.8 0.0 1.2 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_18 PF13238.6 OQR94398.1 - 0.00048 20.7 0.0 0.0011 19.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain CPT PF07931.12 OQR94398.1 - 0.0019 18.0 0.1 0.012 15.5 0.1 2.2 2 1 0 2 2 2 1 Chloramphenicol phosphotransferase-like protein ABC_tran PF00005.27 OQR94398.1 - 0.0068 16.9 0.0 0.013 16.0 0.0 1.6 1 0 0 1 1 1 1 ABC transporter Viral_helicase1 PF01443.18 OQR94398.1 - 0.012 15.4 0.1 0.031 14.0 0.0 1.8 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA_22 PF13401.6 OQR94398.1 - 0.017 15.4 1.0 0.055 13.8 0.1 2.2 2 1 0 2 2 2 0 AAA domain Ploopntkinase3 PF18751.1 OQR94398.1 - 0.018 15.0 0.0 1.9 8.3 0.0 2.3 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 APS_kinase PF01583.20 OQR94398.1 - 0.028 14.3 0.1 0.067 13.1 0.0 1.6 1 1 0 1 1 1 0 Adenylylsulphate kinase NACHT PF05729.12 OQR94398.1 - 0.03 14.3 0.0 0.057 13.3 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA_30 PF13604.6 OQR94398.1 - 0.047 13.4 0.0 0.084 12.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 OQR94398.1 - 0.052 12.8 0.0 0.33 10.2 0.0 2.0 2 0 0 2 2 2 0 Zeta toxin NTPase_1 PF03266.15 OQR94398.1 - 0.12 12.2 0.1 16 5.3 0.0 2.9 2 1 1 3 3 3 0 NTPase DUF2075 PF09848.9 OQR94398.1 - 0.17 11.1 0.2 0.93 8.7 0.2 1.9 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Glyco_hydro_38N PF01074.22 OQR94399.1 - 7.8e-82 274.9 4.3 1.3e-81 274.2 4.3 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.13 OQR94399.1 - 9.5e-32 110.8 0.3 1.8e-31 109.9 0.3 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.11 OQR94399.1 - 2.6e-18 66.0 0.7 6.4e-18 64.7 0.1 2.1 2 0 0 2 2 2 1 Alpha mannosidase middle domain ZZ PF00569.17 OQR94399.1 - 1e-09 38.1 5.7 2e-09 37.1 5.7 1.4 1 0 0 1 1 1 1 Zinc finger, ZZ type C1_2 PF03107.16 OQR94399.1 - 0.077 13.3 6.0 0.21 11.9 6.0 1.7 1 0 0 1 1 1 0 C1 domain STAC2_u1 PF16664.5 OQR94399.1 - 5.9 7.4 8.9 1.8 9.0 4.5 2.4 2 0 0 2 2 2 0 Unstructured on SH3 and cysteine-rich domain-containing protein 2 Ank_2 PF12796.7 OQR94400.1 - 8.1e-17 61.6 8.1 4.5e-05 23.9 0.0 6.5 4 1 3 7 7 7 4 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OQR94400.1 - 5.4e-10 38.6 11.8 0.11 13.1 0.1 8.3 8 0 0 8 8 8 2 Ankyrin repeat Ank_4 PF13637.6 OQR94400.1 - 3e-09 37.2 4.3 0.4 11.3 0.0 6.5 6 0 0 6 6 6 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 OQR94400.1 - 1.8e-08 34.5 13.3 0.025 14.9 0.1 7.9 6 2 2 8 8 8 3 Ankyrin repeats (many copies) Ank PF00023.30 OQR94400.1 - 6.8e-06 26.3 6.1 0.3 11.6 0.1 5.5 6 0 0 6 6 6 3 Ankyrin repeat DAP_B PF07930.12 OQR94400.1 - 0.12 12.4 0.1 0.23 11.4 0.1 1.4 1 0 0 1 1 1 0 D-aminopeptidase, domain B DUF4226 PF10774.9 OQR94400.1 - 3.5 7.9 5.5 29 5.0 0.2 3.2 2 1 0 2 2 2 0 Domain of unknown function (DUF4226) INTS2 PF14750.6 OQR94401.1 - 2e-06 25.8 0.9 2.4e-06 25.5 0.9 1.1 1 0 0 1 1 1 1 Integrator complex subunit 2 5_nucleotid_C PF02872.18 OQR94402.1 - 3.7e-26 92.2 0.0 8e-26 91.1 0.0 1.5 1 0 0 1 1 1 1 5'-nucleotidase, C-terminal domain Metallophos PF00149.28 OQR94402.1 - 0.0017 18.9 0.0 0.0031 18.0 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase MHC_II_beta PF00969.19 OQR94402.1 - 0.067 13.3 0.2 0.17 12.0 0.2 1.6 1 0 0 1 1 1 0 Class II histocompatibility antigen, beta domain Ge1_WD40 PF16529.5 OQR94424.1 - 1.3e-14 53.9 0.0 2.3e-13 49.8 0.0 2.1 1 1 0 1 1 1 1 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40 PF00400.32 OQR94424.1 - 3.8e-08 33.9 1.1 0.0066 17.3 0.1 3.5 3 0 0 3 3 3 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OQR94424.1 - 0.007 16.6 0.1 0.43 10.9 0.0 2.6 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain 7TMR-HDED PF07697.11 OQR94424.1 - 0.31 11.1 3.7 0.62 10.1 3.4 1.5 1 1 0 1 1 1 0 7TM-HD extracellular SPX PF03105.19 OQR94424.1 - 1.1 9.1 7.7 1.9 8.3 7.7 1.3 1 0 0 1 1 1 0 SPX domain Dynein_attach_N PF15867.5 OQR94425.1 - 4.5e-20 71.4 0.6 1.1e-19 70.1 0.6 1.7 1 0 0 1 1 1 1 Dynein attachment factor N-terminus RPAP3_C PF13877.6 OQR94425.1 - 7.9e-14 52.0 0.4 4.6e-13 49.5 0.0 2.4 2 1 1 3 3 3 1 Potential Monad-binding region of RPAP3 Laminin_G_3 PF13385.6 OQR94426.1 - 1.8e-07 31.4 0.0 1.5e-06 28.5 0.0 2.5 2 0 0 2 2 2 1 Concanavalin A-like lectin/glucanases superfamily WD40 PF00400.32 OQR94426.1 - 0.00046 20.9 0.4 0.003 18.3 0.1 2.7 2 0 0 2 2 2 1 WD domain, G-beta repeat Ank_2 PF12796.7 OQR94427.1 - 1.4e-33 115.3 4.4 4.5e-16 59.2 0.6 3.7 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) FH2 PF02181.23 OQR94427.1 - 4.1e-28 98.6 18.4 2e-26 93.0 0.7 5.1 6 0 0 6 6 6 2 Formin Homology 2 Domain Ank_4 PF13637.6 OQR94427.1 - 1.8e-24 85.8 3.2 8.4e-10 39.0 0.6 4.8 3 1 1 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQR94427.1 - 6.6e-20 69.1 5.7 0.01 16.3 0.0 7.5 7 0 0 7 7 7 4 Ankyrin repeat Ank PF00023.30 OQR94427.1 - 1.3e-15 57.0 7.3 0.00017 21.9 0.0 6.0 5 0 0 5 5 5 3 Ankyrin repeat SapB_2 PF03489.17 OQR94427.1 - 3.5e-13 49.4 31.9 0.0096 16.0 0.1 10.1 10 0 0 10 10 10 7 Saposin-like type B, region 2 Ank_5 PF13857.6 OQR94427.1 - 2.8e-11 43.4 5.5 0.00056 20.2 0.7 5.3 1 1 5 6 6 6 3 Ankyrin repeats (many copies) PH_12 PF16457.5 OQR94427.1 - 2.5e-05 24.8 0.4 9e-05 23.0 0.1 2.1 2 0 0 2 2 2 1 Pleckstrin homology domain C2 PF00168.30 OQR94427.1 - 5.4e-05 23.4 0.0 0.00017 21.8 0.0 1.8 1 0 0 1 1 1 1 C2 domain WW PF00397.26 OQR94427.1 - 7e-05 22.8 6.3 7e-05 22.8 6.3 1.9 2 0 0 2 2 2 1 WW domain PH PF00169.29 OQR94427.1 - 0.00023 21.6 0.1 0.0005 20.5 0.1 1.6 1 0 0 1 1 1 1 PH domain Mcp5_PH PF12814.7 OQR94427.1 - 0.014 15.5 0.2 0.042 14.0 0.2 1.8 1 0 0 1 1 1 0 Meiotic cell cortex C-terminal pleckstrin homology Syntaxin_2 PF14523.6 OQR94427.1 - 0.1 13.0 0.9 35 4.9 0.0 4.0 3 0 0 3 3 3 0 Syntaxin-like protein KIAA1430 PF13879.6 OQR94428.1 - 9.2e-27 93.8 17.9 1.6e-26 93.0 17.9 1.4 1 0 0 1 1 1 1 KIAA1430 homologue Chromo PF00385.24 OQR94428.1 - 0.07 13.1 0.7 0.21 11.5 0.7 1.9 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain LysE PF01810.18 OQR94429.1 - 4e-14 52.5 8.9 4e-14 52.5 8.9 1.9 2 0 0 2 2 2 1 LysE type translocator MarC PF01914.17 OQR94429.1 - 0.6 9.5 8.2 0.18 11.1 1.6 2.7 3 0 0 3 3 3 0 MarC family integral membrane protein PAN_4 PF14295.6 OQR94430.1 - 0.00078 19.3 2.2 0.0014 18.5 2.2 1.4 1 0 0 1 1 1 1 PAN domain PAN_1 PF00024.26 OQR94430.1 - 0.019 14.9 2.7 0.023 14.7 2.7 1.3 1 0 0 1 1 1 0 PAN domain cNMP_binding PF00027.29 OQR94460.1 - 4.3e-55 183.8 1.9 1.1e-13 51.0 0.1 4.9 4 1 0 4 4 4 4 Cyclic nucleotide-binding domain Ion_trans PF00520.31 OQR94460.1 - 4.2e-51 173.5 102.1 3.5e-27 95.2 8.4 5.3 5 0 0 5 5 5 5 Ion transport protein Ion_trans_2 PF07885.16 OQR94460.1 - 5.8e-09 35.8 30.3 8.5e-09 35.3 2.8 6.9 6 1 0 6 6 6 2 Ion channel zf-B_box PF00643.24 OQR94460.1 - 7.3e-05 22.8 7.9 0.00016 21.7 7.9 1.6 1 0 0 1 1 1 1 B-box zinc finger TelA PF05816.11 OQR94460.1 - 0.081 12.0 0.1 0.18 10.8 0.1 1.5 1 0 0 1 1 1 0 Toxic anion resistance protein (TelA) CEBP_ZZ PF16366.5 OQR94460.1 - 0.14 12.4 6.7 0.34 11.2 6.7 1.7 1 0 0 1 1 1 0 Cytoplasmic polyadenylation element-binding protein ZZ domain PKD_channel PF08016.12 OQR94461.1 - 5.4e-16 58.3 19.5 7.1e-15 54.6 8.5 3.6 4 0 0 4 4 4 2 Polycystin cation channel Ion_trans PF00520.31 OQR94461.1 - 5.2e-08 32.4 7.8 5.2e-08 32.4 7.8 2.7 2 0 0 2 2 2 1 Ion transport protein TrbE PF11100.8 OQR94462.1 - 0.018 15.2 0.5 0.035 14.3 0.5 1.5 1 0 0 1 1 1 0 Conjugal transfer protein TrbE HTH_13 PF11972.8 OQR94462.1 - 0.32 11.1 1.2 0.89 9.7 0.1 2.0 2 0 0 2 2 2 0 HTH DNA binding domain Ammonium_transp PF00909.21 OQR94465.1 - 1.4e-92 310.4 24.4 1.8e-92 310.1 24.4 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family CYSTM PF12734.7 OQR94465.1 - 9.9 6.6 7.3 0.46 10.8 0.7 2.3 2 0 0 2 2 2 0 Cysteine-rich TM module stress tolerance RabGAP-TBC PF00566.18 OQR94523.1 - 5.7e-40 137.3 2.5 8e-36 123.7 1.3 2.2 2 0 0 2 2 2 2 Rab-GTPase-TBC domain FYVE PF01363.21 OQR94523.1 - 3.6e-17 62.2 10.5 8.4e-17 61.1 10.5 1.6 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.16 OQR94523.1 - 0.003 17.7 5.1 0.0076 16.4 5.1 1.6 1 0 0 1 1 1 1 FYVE-type zinc finger zf-B_box PF00643.24 OQR94523.1 - 1.4 9.1 8.3 0.91 9.7 4.5 2.4 2 0 0 2 2 2 0 B-box zinc finger SQS_PSY PF00494.19 OQR94524.1 - 9.8e-41 140.0 0.0 1.3e-40 139.6 0.0 1.1 1 0 0 1 1 1 1 Squalene/phytoene synthase PGK PF00162.19 OQR94525.1 - 7.8e-158 525.3 0.6 9.4e-158 525.1 0.6 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase PH PF00169.29 OQR94526.1 - 1.6e-06 28.6 0.1 4.9e-06 27.0 0.1 1.9 1 0 0 1 1 1 1 PH domain PH_8 PF15409.6 OQR94526.1 - 0.023 14.9 1.8 0.043 14.1 0.0 2.1 2 0 0 2 2 2 0 Pleckstrin homology domain MFS_1 PF07690.16 OQR94528.1 - 2.7e-25 89.0 31.9 2.7e-25 89.0 31.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 OQR94528.1 - 0.00064 18.7 1.1 0.00064 18.7 1.1 3.3 2 2 1 3 3 3 2 Sugar (and other) transporter Beach PF02138.18 OQR94529.1 - 1.1e-115 385.8 0.0 1.9e-115 385.0 0.0 1.4 1 0 0 1 1 1 1 Beige/BEACH domain PH_BEACH PF14844.6 OQR94529.1 - 1.8e-11 44.0 0.1 8.6e-11 41.8 0.1 2.2 2 0 0 2 2 2 1 PH domain associated with Beige/BEACH DUF4704 PF15787.5 OQR94529.1 - 5.7e-11 42.2 1.5 5.7e-11 42.2 1.5 2.2 2 1 0 2 2 2 1 Domain of unknown function (DUF4704) WD40 PF00400.32 OQR94529.1 - 0.0021 18.9 5.5 0.2 12.6 0.3 3.9 3 0 0 3 3 3 2 WD domain, G-beta repeat MFS_1 PF07690.16 OQR94530.1 - 5.5e-26 91.3 28.9 5.5e-26 91.3 28.9 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF3382 PF11862.8 OQR94530.1 - 0.12 12.6 5.2 1.1 9.6 1.0 3.8 4 0 0 4 4 4 0 Domain of unknown function (DUF3382) Hexokinase_2 PF03727.16 OQR94554.1 - 0.06 12.8 0.0 0.091 12.2 0.0 1.2 1 0 0 1 1 1 0 Hexokinase RRM_1 PF00076.22 OQR94555.1 - 2.5e-33 113.7 0.1 3.3e-16 58.8 0.0 3.1 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 OQR94555.1 - 3.4e-09 36.7 0.0 0.0021 18.2 0.0 2.7 2 1 0 2 2 2 2 RNA recognition motif Nup35_RRM_2 PF14605.6 OQR94555.1 - 2.6e-05 24.1 0.0 0.2 11.7 0.0 2.4 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif DUF1866 PF08952.11 OQR94555.1 - 0.019 14.8 0.0 1.2 9.0 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1866) DNA_pol_delta_4 PF04081.13 OQR94555.1 - 0.96 9.8 7.8 2.6 8.4 7.8 1.7 1 0 0 1 1 1 0 DNA polymerase delta, subunit 4 FAM176 PF14851.6 OQR94555.1 - 1.4 8.6 9.5 2.8 7.6 9.5 1.6 1 0 0 1 1 1 0 FAM176 family Presenilin PF01080.17 OQR94555.1 - 8 5.1 5.2 11 4.7 5.2 1.2 1 0 0 1 1 1 0 Presenilin Atg14 PF10186.9 OQR94558.1 - 2.2e-22 79.6 2.7 9.3e-20 70.9 1.2 2.4 2 1 0 2 2 2 1 Vacuolar sorting 38 and autophagy-related subunit 14 Methyltransf_16 PF10294.9 OQR94559.1 - 2e-08 34.2 0.0 2.3e-08 34.0 0.0 1.1 1 0 0 1 1 1 1 Lysine methyltransferase MTS PF05175.14 OQR94559.1 - 1.6e-05 24.5 0.0 1.9e-05 24.3 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.13 OQR94559.1 - 0.00063 19.2 0.0 0.00078 18.9 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.6 OQR94559.1 - 0.025 15.3 0.0 0.034 14.8 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Cons_hypoth95 PF03602.15 OQR94559.1 - 0.029 14.0 0.0 0.037 13.7 0.0 1.2 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Methyltransf_11 PF08241.12 OQR94559.1 - 0.08 13.6 0.0 0.11 13.1 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.6 OQR94559.1 - 0.11 12.3 0.0 0.13 12.1 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.12 OQR94559.1 - 0.12 13.1 0.0 0.15 12.8 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain RNA_pol_A_bac PF01000.26 OQR94560.1 - 4.6e-27 94.6 0.1 5.9e-26 91.0 0.0 2.4 2 0 0 2 2 2 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.24 OQR94560.1 - 3.9e-22 77.5 0.0 5.2e-22 77.1 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Fer4_9 PF13187.6 OQR94560.1 - 0.72 10.1 7.1 0.29 11.3 0.6 2.4 2 0 0 2 2 2 0 4Fe-4S dicluster domain DER1 PF04511.15 OQR94561.1 - 1.2e-17 64.5 2.6 1.3e-17 64.3 2.6 1.1 1 0 0 1 1 1 1 Der1-like family IFT46_B_C PF12317.8 OQR94562.1 - 4.3e-94 314.2 2.6 5.3e-94 313.9 2.6 1.1 1 0 0 1 1 1 1 Intraflagellar transport complex B protein 46 C terminal Dus PF01207.17 OQR94563.1 - 1.9e-70 237.4 0.0 2.3e-70 237.2 0.0 1.1 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) His_biosynth PF00977.21 OQR94563.1 - 0.0034 16.9 0.0 0.006 16.1 0.0 1.3 1 0 0 1 1 1 1 Histidine biosynthesis protein DHO_dh PF01180.21 OQR94563.1 - 0.0037 16.5 0.0 1.2 8.2 0.0 2.1 2 0 0 2 2 2 2 Dihydroorotate dehydrogenase TMP-TENI PF02581.17 OQR94563.1 - 0.019 14.3 0.0 0.031 13.6 0.0 1.4 1 0 0 1 1 1 0 Thiamine monophosphate synthase G3P_antiterm PF04309.12 OQR94563.1 - 0.038 13.4 0.0 0.092 12.2 0.0 1.6 1 0 0 1 1 1 0 Glycerol-3-phosphate responsive antiterminator FMN_dh PF01070.18 OQR94563.1 - 0.045 12.8 0.0 0.066 12.2 0.0 1.2 1 0 0 1 1 1 0 FMN-dependent dehydrogenase zf-RING_4 PF14570.6 OQR94564.1 - 0.015 15.1 0.1 1.2 8.9 0.0 2.3 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain YgbB PF02542.16 OQR94564.1 - 0.14 12.5 1.6 0.24 11.7 0.8 1.7 1 1 0 1 1 1 0 YgbB family zf-UBR PF02207.20 OQR94564.1 - 0.21 11.8 2.0 6.8 6.9 0.2 2.3 1 1 1 2 2 2 0 Putative zinc finger in N-recognin (UBR box) YabA PF06156.13 OQR94564.1 - 0.59 10.8 5.2 0.25 12.0 2.1 1.9 2 0 0 2 2 2 0 Initiation control protein YabA Pro_isomerase PF00160.21 OQR94565.1 - 4.3e-48 163.6 0.1 5.6e-48 163.2 0.1 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD TetR_C_15 PF17918.1 OQR94566.1 - 0.0044 17.8 0.8 0.015 16.0 0.8 2.0 1 0 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain Helicase_C_3 PF13625.6 OQR94566.1 - 0.021 15.0 1.4 0.05 13.8 1.4 1.7 1 0 0 1 1 1 0 Helicase conserved C-terminal domain KASH_CCD PF14662.6 OQR94566.1 - 3.2 7.5 49.0 1.7 8.4 13.7 3.1 1 1 2 3 3 3 0 Coiled-coil region of CCDC155 or KASH DUF3584 PF12128.8 OQR94566.1 - 3.9 4.8 47.3 0.037 11.6 27.0 2.7 1 1 2 3 3 3 0 Protein of unknown function (DUF3584) Aldedh PF00171.22 OQR94568.1 - 4.2e-70 236.6 0.0 5.1e-70 236.3 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF5122 PF17164.4 OQR94568.1 - 0.16 12.3 0.0 0.36 11.1 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF5122) beta-propeller PRP38 PF03371.15 OQR94569.1 - 4.7e-53 179.6 0.4 1e-52 178.5 0.2 1.6 2 0 0 2 2 2 1 PRP38 family SMN PF06003.12 OQR94569.1 - 1.8e-06 27.4 1.9 1.8e-06 27.4 1.9 2.3 1 1 1 2 2 2 1 Survival motor neuron protein (SMN) CDC45 PF02724.14 OQR94569.1 - 0.75 8.0 16.3 1.1 7.4 16.3 1.3 1 0 0 1 1 1 0 CDC45-like protein PUB PF09409.10 OQR94592.1 - 6.1e-39 131.8 0.0 1.4e-15 57.0 0.0 3.8 3 0 0 3 3 3 3 PUB domain TUDOR_5 PF18359.1 OQR94592.1 - 2.5e-24 84.7 22.8 3.9e-07 29.7 0.4 6.9 6 0 0 6 6 6 4 Histone methyltransferase Tudor domain 1 Agenet PF05641.12 OQR94592.1 - 7.7e-15 55.1 18.7 0.038 14.4 0.2 8.4 8 0 0 8 8 8 4 Agenet domain DUF4537 PF15057.6 OQR94592.1 - 2.3e-14 53.5 14.4 0.00017 21.6 2.1 5.7 3 2 3 6 6 6 4 Domain of unknown function (DUF4537) EF-hand_7 PF13499.6 OQR94592.1 - 2.3e-11 44.0 0.1 3.2e-08 33.9 0.0 3.2 2 0 0 2 2 2 1 EF-hand domain pair Tudor_2 PF18104.1 OQR94592.1 - 9.5e-09 34.8 21.8 0.019 14.7 0.6 7.3 8 0 0 8 8 8 3 Jumonji domain-containing protein 2A Tudor domain DUF1325 PF07039.11 OQR94592.1 - 7.6e-08 32.5 7.6 0.064 13.3 0.2 6.0 3 2 2 5 5 4 3 SGF29 tudor-like domain EF-hand_1 PF00036.32 OQR94592.1 - 7.9e-07 28.2 0.7 0.0029 17.0 0.7 4.0 3 0 0 3 3 3 1 EF hand EF-hand_6 PF13405.6 OQR94592.1 - 8.7e-07 28.4 2.6 0.64 10.1 0.0 4.4 4 0 0 4 4 3 2 EF-hand domain TUDOR PF00567.24 OQR94592.1 - 2.2e-05 24.5 2.1 0.00088 19.3 0.3 4.1 3 2 2 5 5 5 1 Tudor domain LBR_tudor PF09465.10 OQR94592.1 - 0.0026 17.5 15.2 0.53 10.1 0.3 7.4 8 1 0 8 8 8 1 Lamin-B receptor of TUDOR domain EF-hand_8 PF13833.6 OQR94592.1 - 0.0086 15.9 2.3 0.028 14.3 0.6 2.6 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_5 PF13202.6 OQR94592.1 - 0.011 15.3 0.5 0.046 13.2 0.2 2.3 2 0 0 2 2 2 0 EF hand SH3_2 PF07653.17 OQR94592.1 - 0.022 14.5 0.9 4.6 7.0 0.0 3.8 4 1 0 4 4 4 0 Variant SH3 domain EF-hand_4 PF12763.7 OQR94592.1 - 0.033 14.2 0.1 7.2 6.6 0.0 3.1 2 0 0 2 2 2 0 Cytoskeletal-regulatory complex EF hand 53-BP1_Tudor PF09038.10 OQR94592.1 - 0.035 14.1 14.6 0.47 10.4 0.8 5.7 5 1 0 6 6 6 0 Tumour suppressor p53-binding protein-1 Tudor Zip PF02535.22 OQR94592.1 - 2.7 7.1 9.2 0.054 12.7 1.0 2.4 2 0 0 2 2 2 0 ZIP Zinc transporter Pkinase PF00069.25 OQR94593.1 - 0.0016 17.9 0.1 0.012 15.0 0.1 1.9 1 1 0 1 1 1 1 Protein kinase domain ADK PF00406.22 OQR94594.1 - 1.2e-46 158.5 0.0 1.5e-46 158.2 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 OQR94594.1 - 4.5e-25 88.7 0.0 8.3e-25 87.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 OQR94594.1 - 2.4e-07 31.4 0.0 5.2e-07 30.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 OQR94594.1 - 0.00031 20.9 0.0 0.0014 18.8 0.0 2.0 1 1 0 1 1 1 1 AAA domain Hydin_ADK PF17213.3 OQR94594.1 - 0.00044 20.6 3.1 0.58 10.4 0.1 2.8 2 1 1 3 3 3 2 Hydin Adenylate kinase-like domain ADK_lid PF05191.14 OQR94594.1 - 0.0029 17.5 1.8 0.01 15.8 0.0 2.6 2 2 0 2 2 2 1 Adenylate kinase, active site lid Cytidylate_kin PF02224.18 OQR94594.1 - 0.0076 16.0 0.0 0.011 15.5 0.0 1.3 1 0 0 1 1 1 1 Cytidylate kinase Thymidylate_kin PF02223.17 OQR94594.1 - 0.093 12.4 0.0 1.5 8.5 0.0 2.3 2 0 0 2 2 2 0 Thymidylate kinase CDC24_OB3 PF17244.2 OQR94594.1 - 0.13 11.9 0.0 0.17 11.6 0.0 1.2 1 0 0 1 1 1 0 Cell division control protein 24, OB domain 3 Pkinase PF00069.25 OQR94595.1 - 1.7e-34 119.4 0.0 2.3e-34 119.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQR94595.1 - 2.9e-27 95.6 0.0 3.5e-27 95.3 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OQR94595.1 - 0.0081 15.5 0.0 0.0098 15.2 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 OQR94595.1 - 0.016 14.6 0.0 0.021 14.2 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OQR94595.1 - 0.044 13.7 0.0 0.063 13.2 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Ank_2 PF12796.7 OQR94596.1 - 7e-84 276.5 50.9 1.2e-14 54.6 1.3 10.5 3 2 8 12 12 12 11 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQR94596.1 - 1.6e-64 213.5 26.5 1.3e-07 32.0 0.2 14.7 8 4 7 15 15 15 15 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQR94596.1 - 1.8e-60 193.7 38.8 8.1e-05 22.7 0.1 19.6 22 0 0 22 22 22 14 Ankyrin repeat Ank PF00023.30 OQR94596.1 - 1.3e-58 193.0 39.5 6e-08 32.8 0.3 18.9 19 0 0 19 19 19 12 Ankyrin repeat Ank_5 PF13857.6 OQR94596.1 - 2.4e-56 187.1 34.3 2.9e-08 33.8 0.6 13.6 7 4 7 14 14 14 11 Ankyrin repeats (many copies) YebO PF13974.6 OQR94596.1 - 0.058 13.5 4.1 0.42 10.7 0.8 3.7 2 1 1 3 3 3 0 YebO-like protein Pkinase PF00069.25 OQR94597.1 - 2.2e-23 82.9 0.0 2.6e-23 82.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQR94597.1 - 5.1e-18 65.3 0.0 5.9e-18 65.1 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase DUF3149 PF11346.8 OQR94598.1 - 0.1 12.3 0.1 0.1 12.3 0.1 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3149) TIM21 PF08294.11 OQR94598.1 - 4.2 7.2 5.7 11 5.9 0.4 2.6 2 0 0 2 2 2 0 TIM21 CBM_1 PF00734.18 OQR94599.1 - 4.4e-90 295.2 154.1 7.8e-10 38.5 7.4 11.6 11 0 0 11 11 11 10 Fungal cellulose binding domain DUF5629 PF18629.1 OQR94599.1 - 0.0021 18.6 3.4 10 6.8 0.1 4.3 4 0 0 4 4 4 2 Family of unknown function (DUF5629) HOIP-UBA PF16678.5 OQR94599.1 - 0.066 13.2 1.8 11 6.0 0.0 3.4 3 0 0 3 3 3 0 HOIP UBA domain pair TPR_8 PF13181.6 OQR94616.1 - 2.9e-20 70.7 11.1 9e-05 22.4 0.0 6.3 6 0 0 6 6 6 6 Tetratricopeptide repeat TPR_2 PF07719.17 OQR94616.1 - 7.3e-19 66.3 9.6 8.3e-05 22.4 0.0 6.4 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_1 PF00515.28 OQR94616.1 - 7.8e-17 60.3 13.6 6.3e-06 25.8 0.0 6.4 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_11 PF13414.6 OQR94616.1 - 8.5e-17 60.6 10.3 0.0053 16.4 0.3 5.2 3 1 2 5 5 5 4 TPR repeat TPR_17 PF13431.6 OQR94616.1 - 3.2e-16 58.4 6.7 0.027 14.8 0.0 5.6 4 1 1 5 5 5 4 Tetratricopeptide repeat TPR_7 PF13176.6 OQR94616.1 - 1.7e-15 55.8 5.1 0.039 14.0 0.0 6.2 5 1 1 6 6 6 4 Tetratricopeptide repeat TPR_14 PF13428.6 OQR94616.1 - 7.9e-15 54.3 10.8 0.0006 20.4 0.0 5.3 1 1 4 5 5 5 4 Tetratricopeptide repeat TPR_19 PF14559.6 OQR94616.1 - 7.8e-14 51.9 15.9 2.2e-05 24.9 0.1 3.8 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.6 OQR94616.1 - 3.5e-12 46.7 11.3 2.3e-05 24.9 0.3 3.3 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.6 OQR94616.1 - 2.2e-11 43.9 13.3 0.025 14.9 0.0 5.2 1 1 2 4 4 4 4 Tetratricopeptide repeat TPR_6 PF13174.6 OQR94616.1 - 4.8e-11 42.5 10.7 0.11 13.2 0.0 6.1 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_9 PF13371.6 OQR94616.1 - 1.2e-08 35.0 2.9 0.001 19.2 0.0 3.4 3 1 1 4 4 4 2 Tetratricopeptide repeat ANAPC3 PF12895.7 OQR94616.1 - 3.1e-08 33.7 4.7 0.005 17.0 0.0 3.6 1 1 3 4 4 4 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.6 OQR94616.1 - 3.6e-08 33.0 9.0 0.00037 19.8 0.2 3.1 1 1 2 3 3 3 3 Tetratricopeptide repeat BTAD PF03704.17 OQR94616.1 - 4.3e-05 24.0 1.6 0.0061 17.0 0.4 2.6 2 1 0 2 2 2 1 Bacterial transcriptional activator domain DUF2989 PF11207.8 OQR94616.1 - 0.00038 20.3 9.4 0.031 14.0 1.0 2.4 1 1 0 2 2 2 2 Protein of unknown function (DUF2989) TPR_20 PF14561.6 OQR94616.1 - 0.00073 19.8 16.8 0.017 15.4 0.6 3.4 3 1 1 4 4 4 2 Tetratricopeptide repeat PPR PF01535.20 OQR94616.1 - 0.0013 18.9 0.1 0.085 13.1 0.0 3.3 3 0 0 3 3 3 1 PPR repeat Sel1 PF08238.12 OQR94616.1 - 0.005 17.5 0.8 0.021 15.5 0.1 2.5 2 0 0 2 2 1 1 Sel1 repeat TPR_10 PF13374.6 OQR94616.1 - 0.0079 16.0 12.9 10 6.1 0.0 6.5 5 2 1 6 6 6 0 Tetratricopeptide repeat Rapsyn_N PF10579.9 OQR94616.1 - 0.0087 16.1 0.1 0.15 12.1 0.0 2.4 2 0 0 2 2 2 1 Rapsyn N-terminal myristoylation and linker region DUF4810 PF16068.5 OQR94616.1 - 0.017 15.7 7.1 0.11 13.1 0.0 4.3 1 1 3 4 4 4 0 Domain of unknown function (DUF4810) Drf_FH3 PF06367.16 OQR94616.1 - 0.035 13.7 0.0 0.19 11.3 0.0 2.2 2 1 0 2 2 2 0 Diaphanous FH3 Domain PsbP PF01789.16 OQR94616.1 - 0.09 12.9 1.5 0.74 9.9 1.5 2.3 1 1 0 1 1 1 0 PsbP DUF3731 PF12531.8 OQR94616.1 - 0.14 11.9 2.2 0.96 9.2 0.1 2.5 2 1 0 2 2 2 0 DNA-K related protein TPR_3 PF07720.12 OQR94616.1 - 1.1 9.4 0.0 1.1 9.4 0.0 4.4 5 0 0 5 5 4 0 Tetratricopeptide repeat MAS20 PF02064.15 OQR94616.1 - 2.4 8.3 11.7 0.05 13.7 4.0 2.1 2 1 0 2 2 2 0 MAS20 protein import receptor LRR_4 PF12799.7 OQR94617.1 - 0.0024 18.2 12.9 0.02 15.3 2.4 5.0 3 3 1 4 4 4 1 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 OQR94617.1 - 0.057 13.4 0.7 0.14 12.2 0.7 1.5 1 1 0 1 1 1 0 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 OQR94617.1 - 0.18 11.6 8.2 1.1 9.1 0.2 4.3 4 2 1 5 5 5 0 Leucine rich repeat LRR_6 PF13516.6 OQR94617.1 - 0.39 10.9 2.9 3 8.1 0.2 3.4 3 0 0 3 3 3 0 Leucine Rich repeat LRR_1 PF00560.33 OQR94617.1 - 6.1 7.8 9.6 1.3 9.9 2.2 3.7 5 1 0 5 5 5 0 Leucine Rich Repeat bZIP_1 PF00170.21 OQR94618.1 - 0.073 13.2 6.6 0.16 12.1 6.6 1.6 1 0 0 1 1 1 0 bZIP transcription factor Apt1 PF10351.9 OQR94618.1 - 0.14 10.9 5.4 0.17 10.7 5.4 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain FapA PF03961.13 OQR94618.1 - 0.42 9.1 1.9 0.48 9.0 1.9 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A Proteasom_PSMB PF10508.9 OQR94619.1 - 2.1e-31 109.0 3.6 1.3e-20 73.4 0.0 2.1 2 0 0 2 2 2 2 Proteasome non-ATPase 26S subunit Utp12 PF04003.12 OQR94619.1 - 0.011 16.1 0.2 8.7 6.7 0.0 2.7 2 0 0 2 2 2 0 Dip2/Utp12 Family IFRD PF05004.13 OQR94619.1 - 0.56 9.3 3.6 0.57 9.2 0.8 2.1 2 0 0 2 2 2 0 Interferon-related developmental regulator (IFRD) HVSL PF09749.9 OQR94620.1 - 6.7e-37 127.2 0.1 8.7e-37 126.9 0.1 1.1 1 0 0 1 1 1 1 Uncharacterised conserved protein HNOBA PF07701.14 OQR94620.1 - 0.078 12.4 0.1 0.14 11.6 0.1 1.4 1 1 0 1 1 1 0 Heme NO binding associated Aha1_N PF09229.11 OQR94642.1 - 4.3e-20 72.3 0.6 8.4e-20 71.4 0.6 1.5 1 0 0 1 1 1 1 Activator of Hsp90 ATPase, N-terminal zf-MYND PF01753.18 OQR94642.1 - 6e-10 39.0 15.8 1.1e-09 38.2 15.8 1.5 1 0 0 1 1 1 1 MYND finger DUF4685 PF15737.5 OQR94642.1 - 0.019 15.4 1.3 0.034 14.6 1.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4685) PolC_DP2 PF03833.13 OQR94642.1 - 0.051 11.4 6.1 0.07 11.0 6.1 1.2 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 SR-25 PF10500.9 OQR94642.1 - 0.078 12.6 11.0 0.098 12.3 11.0 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein zf-C6H2 PF15801.5 OQR94642.1 - 0.11 12.9 12.0 0.27 11.6 12.0 1.6 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding DUF1079 PF06435.11 OQR94642.1 - 0.31 11.3 0.2 0.31 11.3 0.2 2.0 2 0 0 2 2 2 0 Repeat of unknown function (DUF1079) zf-Mss51 PF13824.6 OQR94642.1 - 0.36 11.0 5.3 1 9.5 5.3 1.8 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 RWP-RK PF02042.15 OQR94643.1 - 3.6e-13 49.3 0.0 5.6e-13 48.6 0.0 1.3 1 0 0 1 1 1 1 RWP-RK domain Indigoidine_A PF04227.12 OQR94644.1 - 3.7e-124 413.8 5.2 3.7e-124 413.8 5.2 1.6 2 0 0 2 2 2 1 Indigoidine synthase A like protein Pyr_redox_2 PF07992.14 OQR94644.1 - 2.2e-51 174.9 0.1 3.8e-51 174.1 0.1 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase PfkB PF00294.24 OQR94644.1 - 3.2e-31 108.7 4.6 2.7e-30 105.7 3.1 2.8 2 1 0 2 2 2 1 pfkB family carbohydrate kinase Pyr_redox_dim PF02852.22 OQR94644.1 - 3.3e-24 85.3 0.0 1.2e-23 83.4 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 OQR94644.1 - 1.6e-16 60.7 1.3 1.8e-13 50.8 0.0 3.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 OQR94644.1 - 4.4e-11 42.6 0.1 1.7e-07 30.8 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 OQR94644.1 - 3.5e-06 26.4 0.5 1.1e-05 24.7 0.4 1.9 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.14 OQR94644.1 - 0.00067 18.5 0.1 0.0018 17.0 0.1 1.8 1 0 0 1 1 1 1 HI0933-like protein FAD_oxidored PF12831.7 OQR94644.1 - 0.00085 18.8 0.1 0.0016 17.9 0.1 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 OQR94644.1 - 0.001 18.4 0.1 0.0044 16.3 0.1 2.1 1 0 0 1 1 1 1 Thi4 family NAD_binding_8 PF13450.6 OQR94644.1 - 0.0013 18.9 3.2 0.015 15.5 0.3 2.8 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 OQR94644.1 - 0.0015 18.2 0.8 0.17 11.4 0.2 2.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 OQR94644.1 - 0.0026 17.1 0.1 0.44 9.8 0.0 2.8 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain GIDA PF01134.22 OQR94644.1 - 0.0026 16.9 2.0 0.0066 15.6 0.1 2.3 2 0 0 2 2 2 1 Glucose inhibited division protein A Tombus_P19 PF03220.13 OQR94644.1 - 0.1 12.3 0.5 6.7 6.4 0.0 2.4 2 0 0 2 2 2 0 Tombusvirus P19 core protein TPP_enzyme_N PF02776.18 OQR94644.1 - 0.1 12.2 0.2 0.24 11.0 0.2 1.5 1 0 0 1 1 1 0 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain Phage-MuB_C PF09077.11 OQR94644.1 - 0.16 11.9 0.9 25 4.8 0.0 3.0 3 0 0 3 3 2 0 Mu B transposition protein, C terminal TIM PF00121.18 OQR94645.1 - 3.5e-86 288.5 0.1 4e-86 288.3 0.1 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase Arm-DNA-bind_3 PF13356.6 OQR94645.1 - 0.09 13.2 0.1 0.24 11.8 0.0 1.7 2 0 0 2 2 2 0 Arm DNA-binding domain EF-hand_7 PF13499.6 OQR94659.1 - 1e-09 38.7 2.9 1.1e-09 38.6 0.8 2.1 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 OQR94659.1 - 7.7e-08 31.7 0.2 0.0051 16.6 0.0 2.6 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.32 OQR94659.1 - 1.8e-07 30.2 0.1 0.00052 19.4 0.1 2.7 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 OQR94659.1 - 5e-05 23.1 0.8 0.27 11.1 0.1 2.9 3 0 0 3 3 3 2 EF-hand domain pair TUDOR_5 PF18359.1 OQR94659.1 - 6.7e-05 22.5 0.1 0.00013 21.6 0.1 1.4 1 0 0 1 1 1 1 Histone methyltransferase Tudor domain 1 SPARC_Ca_bdg PF10591.9 OQR94659.1 - 0.00016 22.0 2.1 0.00016 22.0 2.1 2.6 4 0 0 4 4 4 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_9 PF14658.6 OQR94659.1 - 0.004 17.4 0.4 0.011 16.0 0.1 1.9 2 0 0 2 2 2 1 EF-hand domain Med30 PF11315.8 OQR94659.1 - 0.0043 17.2 0.5 0.0043 17.2 0.5 3.0 1 1 1 3 3 3 1 Mediator complex subunit 30 Agenet PF05641.12 OQR94659.1 - 0.016 15.7 2.8 0.037 14.5 2.8 1.6 1 0 0 1 1 1 0 Agenet domain DUF3726 PF12525.8 OQR94659.1 - 0.088 12.9 0.1 0.29 11.3 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3726) EF-hand_5 PF13202.6 OQR94659.1 - 0.13 11.8 1.1 1.9 8.1 0.1 3.0 3 0 0 3 3 3 0 EF hand YojJ PF10372.9 OQR94659.1 - 0.14 12.2 4.0 11 6.2 0.3 3.3 3 0 0 3 3 3 0 Bacterial membrane-spanning protein N-terminus DUF1664 PF07889.12 OQR94659.1 - 0.21 11.6 17.4 0.99 9.5 1.9 3.4 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) JIP_LZII PF16471.5 OQR94659.1 - 0.88 9.8 17.7 0.075 13.2 2.0 3.7 3 1 1 4 4 4 0 JNK-interacting protein leucine zipper II Spc7 PF08317.11 OQR94659.1 - 6.4 5.6 29.0 0.67 8.8 6.2 2.4 1 1 1 2 2 2 0 Spc7 kinetochore protein p25-alpha PF05517.12 OQR94659.1 - 7.7 6.7 8.0 0.66 10.1 0.7 2.6 2 1 0 2 2 2 0 p25-alpha C2 PF00168.30 OQR94660.1 - 2.3e-93 307.3 2.5 1.3e-18 67.2 0.0 8.4 8 0 0 8 8 8 8 C2 domain FerI PF08151.12 OQR94660.1 - 9.6e-05 22.4 0.0 0.00087 19.3 0.0 2.4 2 0 0 2 2 2 1 FerI (NUC094) domain DOCK-C2 PF14429.6 OQR94660.1 - 0.021 14.6 0.0 0.62 9.8 0.0 2.6 2 0 0 2 2 2 0 C2 domain in Dock180 and Zizimin proteins NT-C2 PF10358.9 OQR94660.1 - 0.024 14.4 2.0 0.052 13.3 0.0 2.6 3 0 0 3 3 3 0 N-terminal C2 in EEIG1 and EHBP1 proteins Ferlin_C PF16165.5 OQR94660.1 - 0.026 14.5 0.1 0.23 11.4 0.0 2.2 2 0 0 2 2 2 0 Ferlin C-terminus AIF-MLS PF14962.6 OQR94660.1 - 0.58 10.1 3.0 0.25 11.3 0.5 1.6 2 0 0 2 2 2 0 Mitochondria Localisation Sequence RT_RNaseH PF17917.1 OQR94661.1 - 0.063 13.6 0.0 0.99 9.7 0.0 2.7 3 0 0 3 3 3 0 RNase H-like domain found in reverse transcriptase PIN_6 PF17146.4 OQR94661.1 - 0.086 13.4 0.8 7.8 7.1 0.2 3.3 3 0 0 3 3 3 0 PIN domain of ribonuclease Raptor_N PF14538.6 OQR94661.1 - 0.45 10.4 4.2 8.8 6.3 0.3 3.3 3 0 0 3 3 3 0 Raptor N-terminal CASPase like domain Lipase_3 PF01764.25 OQR94662.1 - 6.9e-14 51.9 0.0 2e-13 50.4 0.0 1.8 1 1 0 1 1 1 1 Lipase (class 3) TRP PF06011.12 OQR94663.1 - 3.7e-15 55.6 30.7 8.9e-15 54.3 30.7 1.6 1 1 0 1 1 1 1 Transient receptor potential (TRP) ion channel Phage_holin_3_6 PF07332.11 OQR94663.1 - 0.24 11.4 0.0 0.24 11.4 0.0 4.6 3 1 1 4 4 4 0 Putative Actinobacterial Holin-X, holin superfamily III DUF3382 PF11862.8 OQR94663.1 - 0.29 11.4 0.1 0.29 11.4 0.1 3.6 4 0 0 4 4 4 0 Domain of unknown function (DUF3382) TarH PF02203.15 OQR94663.1 - 6.1 6.7 6.2 1.9 8.4 0.2 2.6 3 0 0 3 3 3 0 Tar ligand binding domain homologue PP2C PF00481.21 OQR94664.1 - 4.9e-50 170.6 0.0 5.9e-49 167.0 0.0 2.0 1 1 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 OQR94664.1 - 7.7e-05 22.4 0.1 0.00022 21.0 0.0 1.8 1 1 1 2 2 2 1 Protein phosphatase 2C Kelch_1 PF01344.25 OQR94665.1 - 4.2e-42 141.5 2.9 8.2e-11 41.3 0.0 6.2 6 0 0 6 6 6 5 Kelch motif Kelch_2 PF07646.15 OQR94665.1 - 4.4e-41 137.4 9.5 6.7e-09 35.4 0.4 6.6 6 0 0 6 6 6 6 Kelch motif Kelch_6 PF13964.6 OQR94665.1 - 8.6e-41 136.9 5.9 3.5e-09 36.6 0.2 6.4 5 1 1 6 6 6 6 Kelch motif Kelch_3 PF13415.6 OQR94665.1 - 1.9e-37 126.8 3.3 3.6e-08 33.5 0.1 7.5 7 1 0 7 7 7 6 Galactose oxidase, central domain Kelch_4 PF13418.6 OQR94665.1 - 8.1e-35 118.6 7.7 1.9e-08 34.2 0.0 6.4 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_5 PF13854.6 OQR94665.1 - 6.9e-32 108.9 1.9 2e-07 30.8 0.0 5.7 5 0 0 5 5 5 5 Kelch motif BTB PF00651.31 OQR94665.1 - 7.3e-23 80.9 0.4 3.9e-22 78.6 0.1 2.1 1 1 1 2 2 2 1 BTB/POZ domain Glyco_transf_15 PF01793.16 OQR94665.1 - 0.17 11.1 0.1 0.31 10.3 0.1 1.3 1 0 0 1 1 1 0 Glycolipid 2-alpha-mannosyltransferase Myotub-related PF06602.14 OQR94666.1 - 3.2e-122 407.8 0.2 4.3e-122 407.4 0.2 1.1 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain DSPc PF00782.20 OQR94666.1 - 0.00047 20.0 0.0 0.00094 19.0 0.0 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 OQR94666.1 - 0.00061 19.8 0.0 0.0011 19.0 0.0 1.5 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 OQR94666.1 - 0.0032 17.1 0.0 0.0056 16.3 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase zf-primase PF09329.11 OQR94666.1 - 0.031 14.1 0.2 0.085 12.7 0.2 1.7 1 0 0 1 1 1 0 Primase zinc finger zf-RanBP PF00641.18 OQR94666.1 - 0.11 11.9 9.4 0.019 14.3 3.7 2.3 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others Gag_spuma PF03276.14 OQR94666.1 - 0.56 8.6 2.6 0.84 8.0 2.6 1.1 1 0 0 1 1 1 0 Spumavirus gag protein Transket_pyr PF02779.24 OQR94667.1 - 1.2e-58 197.7 0.0 2.3e-58 196.8 0.0 1.5 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain OxoGdeHyase_C PF16870.5 OQR94667.1 - 5.6e-50 169.0 0.0 1.2e-49 167.9 0.0 1.6 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase C-terminal E1_dh PF00676.20 OQR94667.1 - 6.2e-49 166.5 0.0 9.6e-49 165.9 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component Myosin_head PF00063.21 OQR94668.1 - 4.2e-213 709.4 2.9 6.1e-213 708.8 2.9 1.2 1 0 0 1 1 1 1 Myosin head (motor domain) IQ PF00612.27 OQR94668.1 - 4.2e-14 50.9 17.7 0.0006 19.4 0.1 4.8 4 0 0 4 4 4 4 IQ calmodulin-binding motif WW PF00397.26 OQR94668.1 - 8.1e-08 32.2 0.0 1.4e-07 31.5 0.0 1.4 1 0 0 1 1 1 1 WW domain UPF0242 PF06785.11 OQR94668.1 - 0.00075 19.7 7.8 0.0019 18.3 7.8 1.7 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0242) N-terminus AAA_16 PF13191.6 OQR94668.1 - 0.01 16.3 0.0 0.036 14.5 0.0 2.0 1 0 0 1 1 1 1 AAA ATPase domain INTS5_N PF14837.6 OQR94668.1 - 0.012 15.2 0.2 2.1 7.9 0.0 2.5 2 0 0 2 2 2 0 Integrator complex subunit 5 N-terminus AAA_22 PF13401.6 OQR94668.1 - 0.039 14.2 0.2 0.35 11.1 0.0 2.7 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 OQR94668.1 - 0.2 10.9 3.4 0.31 10.3 0.2 2.4 2 0 0 2 2 2 0 Zeta toxin TMF_DNA_bd PF12329.8 OQR94668.1 - 0.98 9.5 7.7 0.27 11.3 0.4 2.8 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding FAM76 PF16046.5 OQR94668.1 - 1.7 7.9 5.6 4 6.7 5.6 1.6 1 0 0 1 1 1 0 FAM76 protein ABC_tran PF00005.27 OQR94668.1 - 3 8.3 4.7 2.1 8.9 0.5 2.8 2 1 0 2 2 2 0 ABC transporter Chitin_synth_1 PF01644.17 OQR94669.1 - 6.4e-42 143.3 0.0 1.4e-41 142.2 0.0 1.6 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_2 PF03142.15 OQR94669.1 - 3.8e-26 91.8 0.1 6e-22 77.9 0.1 2.4 2 0 0 2 2 2 2 Chitin synthase FGGY_C PF02782.16 OQR94669.1 - 9.5e-24 84.2 0.3 2.2e-23 83.0 0.3 1.6 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.21 OQR94669.1 - 2.7e-17 63.1 0.0 5.7e-17 62.1 0.0 1.6 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain Glyco_trans_2_3 PF13632.6 OQR94669.1 - 2.9e-13 50.2 1.3 8.1e-13 48.7 1.0 2.0 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Chitin_synth_1N PF08407.11 OQR94669.1 - 3.9e-10 39.5 0.1 1e-09 38.2 0.1 1.7 1 0 0 1 1 1 1 Chitin synthase N-terminal MIT PF04212.18 OQR94669.1 - 1.4e-09 37.9 0.0 3.3e-09 36.7 0.0 1.7 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain Glyco_tranf_2_3 PF13641.6 OQR94669.1 - 2.3e-08 34.2 0.0 5.9e-08 32.9 0.0 1.8 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 OQR94669.1 - 0.029 13.8 0.0 9.3 5.7 0.0 2.6 2 0 0 2 2 2 0 Glycosyl transferase family 21 Pkinase PF00069.25 OQR94718.1 - 5.1e-48 163.7 0.0 6.5e-48 163.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQR94718.1 - 4.6e-42 144.1 0.0 6.4e-42 143.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OQR94718.1 - 0.00046 19.1 0.1 0.00066 18.6 0.1 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 OQR94718.1 - 0.01 15.2 0.0 0.029 13.7 0.0 1.7 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Nucleoside_tran PF01733.18 OQR94718.1 - 0.034 13.6 0.3 0.055 12.9 0.3 1.3 1 0 0 1 1 1 0 Nucleoside transporter Haspin_kinase PF12330.8 OQR94718.1 - 0.068 12.1 0.0 0.12 11.3 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain Oxidored_FMN PF00724.20 OQR94719.1 - 6.2e-45 153.9 1.4 8.7e-41 140.3 1.4 3.0 1 1 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Arf PF00025.21 OQR94720.1 - 5.9e-72 240.8 0.2 6.7e-72 240.6 0.2 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.20 OQR94720.1 - 3.8e-14 52.6 0.4 1.4e-09 37.6 0.0 2.4 1 1 1 2 2 2 2 G-protein alpha subunit Roc PF08477.13 OQR94720.1 - 1e-12 48.3 0.0 1.5e-12 47.8 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 OQR94720.1 - 5.5e-12 45.5 0.0 6.3e-12 45.3 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.22 OQR94720.1 - 1.1e-11 44.5 0.0 1.3e-11 44.3 0.0 1.0 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 OQR94720.1 - 1.3e-09 37.8 0.0 1.5e-09 37.6 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 OQR94720.1 - 4.6e-07 29.9 0.0 7.1e-07 29.3 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 OQR94720.1 - 0.0017 17.9 0.0 0.017 14.7 0.0 1.9 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain AAA_18 PF13238.6 OQR94720.1 - 0.016 15.7 0.1 0.033 14.8 0.1 1.6 1 1 0 1 1 1 0 AAA domain PduV-EutP PF10662.9 OQR94720.1 - 0.028 14.2 0.0 0.051 13.3 0.0 1.4 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation PAE PF03283.13 OQR94720.1 - 0.052 12.7 0.0 0.06 12.5 0.0 1.1 1 0 0 1 1 1 0 Pectinacetylesterase cobW PF02492.19 OQR94720.1 - 0.09 12.4 0.0 0.76 9.3 0.0 2.0 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain NACHT PF05729.12 OQR94720.1 - 0.13 12.2 0.2 1.6 8.6 0.0 2.4 2 1 0 2 2 2 0 NACHT domain Vac14_Fig4_bd PF11916.8 OQR94721.1 - 7.2e-61 205.0 11.6 1.3e-59 200.9 9.2 3.2 2 1 0 2 2 2 1 Vacuolar protein 14 C-terminal Fig4p binding Vac14_Fab1_bd PF12755.7 OQR94721.1 - 6.2e-48 161.4 0.1 2.9e-41 140.0 0.1 4.4 3 1 1 4 4 4 2 Vacuolar 14 Fab1-binding region HEAT PF02985.22 OQR94721.1 - 3.8e-16 57.8 4.1 2e-05 24.4 0.0 7.1 7 0 0 7 7 7 4 HEAT repeat Cnd1 PF12717.7 OQR94721.1 - 3.4e-12 46.7 1.5 0.00019 21.5 0.0 4.8 3 1 2 5 5 5 3 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 OQR94721.1 - 2.8e-09 37.3 0.0 0.0073 16.8 0.0 4.5 4 0 0 4 4 3 2 HEAT-like repeat CLASP_N PF12348.8 OQR94721.1 - 7.6e-07 28.9 0.5 0.029 13.9 0.0 4.7 3 2 2 5 5 5 1 CLASP N terminal HEAT_2 PF13646.6 OQR94721.1 - 1.5e-06 28.5 0.5 0.92 9.9 0.0 5.6 6 2 0 6 6 6 2 HEAT repeats Tti2 PF10521.9 OQR94721.1 - 7e-06 25.8 3.3 0.0047 16.5 0.0 3.7 3 1 1 4 4 4 2 Tti2 family RasGEF_N_2 PF14663.6 OQR94721.1 - 0.00099 19.5 0.6 4.1 7.9 0.0 3.8 4 0 0 4 4 4 2 Rapamycin-insensitive companion of mTOR RasGEF_N domain TIP120 PF08623.10 OQR94721.1 - 0.0058 16.4 1.1 0.63 9.8 0.2 3.3 3 0 0 3 3 3 1 TATA-binding protein interacting (TIP20) RTP1_C1 PF10363.9 OQR94721.1 - 0.033 14.4 1.2 2.9 8.1 0.3 3.4 3 1 0 3 3 3 0 Required for nuclear transport of RNA pol II C-terminus 1 Lactamase_B_6 PF16661.5 OQR94721.1 - 0.11 11.9 0.1 0.39 10.1 0.1 1.9 1 1 1 2 2 2 0 Metallo-beta-lactamase superfamily domain ParcG PF10274.9 OQR94721.1 - 0.16 12.1 1.3 1.5 8.9 0.4 2.8 2 1 1 3 3 3 0 Parkin co-regulated protein RIX1 PF08167.12 OQR94721.1 - 0.16 11.7 5.4 4 7.2 1.9 3.7 2 1 1 3 3 3 0 rRNA processing/ribosome biogenesis RasGAP PF00616.19 OQR94727.1 - 2.1e-14 53.7 0.4 1.5e-11 44.4 0.1 2.5 1 1 1 2 2 2 2 GTPase-activator protein for Ras-like GTPase DUF999 PF06198.11 OQR94728.1 - 0.16 12.0 0.1 2.8 7.9 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF999) EF-hand_5 PF13202.6 OQR94729.1 - 8.4e-05 21.9 0.1 0.0002 20.7 0.1 1.7 1 0 0 1 1 1 1 EF hand EF-hand_1 PF00036.32 OQR94729.1 - 0.0012 18.3 0.0 0.0035 16.8 0.0 1.9 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 OQR94729.1 - 0.0031 17.3 0.1 0.014 15.3 0.1 2.2 1 0 0 1 1 1 1 EF-hand domain EF-hand_7 PF13499.6 OQR94729.1 - 0.014 15.8 0.4 0.086 13.3 0.4 2.5 1 0 0 1 1 1 0 EF-hand domain pair Histone PF00125.24 OQR94730.1 - 1.3e-52 177.6 0.7 1.4e-52 177.5 0.7 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 OQR94730.1 - 0.0012 19.1 0.0 0.0019 18.5 0.0 1.2 1 0 0 1 1 1 1 CENP-S protein PAF PF15715.5 OQR94730.1 - 0.0012 19.4 1.3 0.0016 19.1 1.3 1.1 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CENP-T_C PF15511.6 OQR94730.1 - 0.0018 18.4 0.1 0.0034 17.5 0.0 1.6 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold CBFD_NFYB_HMF PF00808.23 OQR94730.1 - 0.016 15.5 0.0 0.036 14.3 0.0 1.6 2 0 0 2 2 2 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Rad51 PF08423.11 OQR94732.1 - 3.7e-36 124.7 0.0 4.7e-36 124.4 0.0 1.1 1 0 0 1 1 1 1 Rad51 ATPase PF06745.13 OQR94732.1 - 3.5e-08 33.1 1.3 4.7e-05 22.9 0.1 2.3 2 1 0 2 2 2 2 KaiC AAA_25 PF13481.6 OQR94732.1 - 4.5e-08 32.9 1.2 2.2e-07 30.6 1.2 1.8 1 1 0 1 1 1 1 AAA domain RecA PF00154.21 OQR94732.1 - 1.9e-05 24.3 2.5 0.00013 21.6 2.5 1.9 1 1 0 1 1 1 1 recA bacterial DNA recombination protein AAA_22 PF13401.6 OQR94732.1 - 0.00049 20.4 0.0 0.00086 19.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain DnaB_C PF03796.15 OQR94732.1 - 0.00071 19.0 0.3 0.16 11.3 0.2 2.0 1 1 1 2 2 2 2 DnaB-like helicase C terminal domain DUF2075 PF09848.9 OQR94732.1 - 0.0099 15.2 0.0 0.015 14.6 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) NTPase_P4 PF11602.8 OQR94732.1 - 0.023 13.9 0.1 0.034 13.4 0.1 1.3 1 0 0 1 1 1 0 ATPase P4 of dsRNA bacteriophage phi-12 Zot PF05707.12 OQR94732.1 - 0.024 14.3 0.0 0.028 14.1 0.0 1.2 1 0 0 1 1 1 0 Zonular occludens toxin (Zot) AAA_33 PF13671.6 OQR94732.1 - 0.035 14.3 0.1 0.077 13.2 0.1 1.5 1 1 0 1 1 1 0 AAA domain GP24_25 PF17388.2 OQR94732.1 - 0.073 13.1 0.3 0.19 11.7 0.1 1.7 1 1 1 2 2 2 0 Tail assembly gene products 24 & 25 NACHT PF05729.12 OQR94732.1 - 0.087 12.7 0.0 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 NACHT domain DHHC PF01529.20 OQR94733.1 - 5.4e-21 75.1 8.2 5.4e-21 75.1 8.2 2.4 2 1 0 2 2 2 1 DHHC palmitoyltransferase AgrB PF04647.15 OQR94733.1 - 2 7.7 15.9 0.023 14.0 6.2 2.0 2 0 0 2 2 2 0 Accessory gene regulator B Filament PF00038.21 OQR94734.1 - 0.011 15.4 2.2 0.015 14.9 2.2 1.2 1 0 0 1 1 1 0 Intermediate filament protein Laminin_I PF06008.14 OQR94734.1 - 0.021 14.6 2.5 0.039 13.7 2.5 1.4 1 1 0 1 1 1 0 Laminin Domain I FliD_C PF07195.12 OQR94734.1 - 0.022 14.2 0.9 0.16 11.4 0.5 1.9 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 C-terminus Spectrin PF00435.21 OQR94734.1 - 0.027 14.9 4.2 0.8 10.2 0.8 2.1 1 1 1 2 2 2 0 Spectrin repeat Syntaxin-6_N PF09177.11 OQR94734.1 - 0.032 14.8 1.9 0.37 11.4 0.1 2.1 1 1 1 2 2 2 0 Syntaxin 6, N-terminal BAG PF02179.16 OQR94734.1 - 0.047 14.1 1.0 0.17 12.4 1.0 1.9 1 1 0 1 1 1 0 BAG domain Mod_r PF07200.13 OQR94734.1 - 0.059 13.5 1.7 0.17 12.0 1.7 1.8 1 1 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein Bcr-Abl_Oligo PF09036.10 OQR94734.1 - 0.13 12.3 1.8 11 6.1 0.1 2.4 1 1 0 2 2 2 0 Bcr-Abl oncoprotein oligomerisation domain PI3K_P85_iSH2 PF16454.5 OQR94734.1 - 0.14 11.7 3.4 0.81 9.3 3.4 1.9 1 1 0 1 1 1 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain Prefoldin PF02996.17 OQR94734.1 - 0.15 12.0 3.4 1.2 9.0 0.1 2.3 2 1 0 2 2 2 0 Prefoldin subunit Prefoldin_2 PF01920.20 OQR94734.1 - 0.31 11.0 6.3 3.1 7.8 3.3 2.4 1 1 3 4 4 4 0 Prefoldin subunit TPR_MLP1_2 PF07926.12 OQR94734.1 - 0.89 9.6 7.8 6.5 6.8 1.1 2.1 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein SR-25 PF10500.9 OQR94737.1 - 0.54 9.8 6.9 1 8.9 6.9 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF1180 PF06679.12 OQR94737.1 - 2.9 8.3 6.5 22 5.4 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) Copine PF07002.16 OQR94765.1 - 7.1e-123 408.1 0.0 2.3e-61 207.0 0.0 2.1 2 0 0 2 2 2 2 Copine vWA-TerF-like PF10138.9 OQR94765.1 - 7.8e-20 71.8 0.0 1.1e-08 35.4 0.0 2.4 2 1 0 2 2 2 2 vWA found in TerF C terminus VWA PF00092.28 OQR94765.1 - 1.2e-08 35.4 0.0 0.0014 18.9 0.0 2.4 2 0 0 2 2 2 2 von Willebrand factor type A domain VWA_2 PF13519.6 OQR94765.1 - 0.00028 21.5 0.0 0.74 10.5 0.0 2.7 2 0 0 2 2 2 2 von Willebrand factor type A domain VWA_3 PF13768.6 OQR94765.1 - 0.0025 17.7 0.0 1.4 8.9 0.0 2.5 2 0 0 2 2 2 2 von Willebrand factor type A domain PSII PF00421.19 OQR94765.1 - 0.16 10.6 0.0 2.1 6.9 0.0 2.1 2 0 0 2 2 2 0 Photosystem II protein AHD PF17793.1 OQR94765.1 - 0.21 11.4 0.7 11 5.9 0.1 2.5 2 0 0 2 2 2 0 ANC1 homology domain (AHD) EF-hand_1 PF00036.32 OQR94766.1 - 4e-18 63.6 11.8 1.9e-05 23.9 0.5 4.6 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 OQR94766.1 - 6.4e-17 61.8 9.3 1.5e-09 38.2 1.7 3.1 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 OQR94766.1 - 9.1e-17 59.5 9.3 0.00031 20.4 0.3 4.6 4 1 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 OQR94766.1 - 4.5e-16 58.4 9.0 2.3e-10 40.1 0.3 3.4 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.6 OQR94766.1 - 8.1e-09 34.6 12.4 0.024 14.1 0.4 4.4 4 0 0 4 4 4 4 EF hand SPARC_Ca_bdg PF10591.9 OQR94766.1 - 0.0013 19.0 2.6 0.056 13.8 0.1 2.6 2 1 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 OQR94766.1 - 0.0023 17.9 1.3 0.34 10.9 0.1 2.8 3 0 0 3 3 3 2 Cytoskeletal-regulatory complex EF hand Caleosin PF05042.13 OQR94766.1 - 4.8 7.1 5.7 18 5.2 0.1 3.6 2 2 2 4 4 4 0 Caleosin related protein CAP_GLY PF01302.25 OQR94767.1 - 1e-17 63.9 1.9 2.3e-17 62.8 1.9 1.6 1 0 0 1 1 1 1 CAP-Gly domain TFIID-18kDa PF02269.16 OQR94767.1 - 4.6e-17 61.8 0.1 1.2e-16 60.5 0.1 1.6 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit LRR_9 PF14580.6 OQR94767.1 - 4.3e-11 42.6 0.2 1.7e-06 27.7 0.0 3.0 1 1 1 3 3 3 3 Leucine-rich repeat LRR_4 PF12799.7 OQR94767.1 - 7.5e-09 35.7 18.1 0.0072 16.7 0.8 5.1 1 1 4 6 6 6 5 Leucine Rich repeats (2 copies) Ubiquitin_2 PF14560.6 OQR94767.1 - 1.2e-08 35.3 0.0 3.5e-08 33.8 0.0 1.9 1 0 0 1 1 1 1 Ubiquitin-like domain LRR_8 PF13855.6 OQR94767.1 - 4.5e-06 26.3 16.7 0.01 15.5 1.0 4.4 1 1 3 4 4 4 4 Leucine rich repeat ubiquitin PF00240.23 OQR94767.1 - 0.013 15.2 0.0 0.047 13.4 0.0 2.0 1 0 0 1 1 1 0 Ubiquitin family KNOX1 PF03790.13 OQR94767.1 - 0.024 14.4 0.2 0.076 12.7 0.0 1.9 2 0 0 2 2 2 0 KNOX1 domain LRR_6 PF13516.6 OQR94767.1 - 0.28 11.4 9.6 78 3.7 0.1 5.7 6 0 0 6 6 6 0 Leucine Rich repeat LRR_1 PF00560.33 OQR94767.1 - 0.8 10.5 10.3 1.8e+02 3.3 0.1 5.7 6 0 0 6 6 6 0 Leucine Rich Repeat Ion_trans PF00520.31 OQR94768.1 - 1.6e-168 558.1 76.7 1.9e-43 148.4 13.1 4.2 4 0 0 4 4 4 4 Ion transport protein GPHH PF16905.5 OQR94768.1 - 1.2e-08 34.6 0.0 2.7e-08 33.5 0.0 1.7 1 0 0 1 1 1 1 Voltage-dependent L-type calcium channel, IQ-associated PKD_channel PF08016.12 OQR94768.1 - 3.1e-07 29.4 70.2 7.7e-05 21.5 0.3 9.4 7 2 2 9 9 9 8 Polycystin cation channel RdRP_3 PF00998.23 OQR94768.1 - 0.17 10.6 0.5 2.1 7.0 0.1 2.1 2 0 0 2 2 2 0 Viral RNA dependent RNA polymerase RGS PF00615.19 OQR94769.1 - 4.5e-68 226.9 13.8 7.7e-20 71.3 0.4 4.1 4 0 0 4 4 4 4 Regulator of G protein signaling domain Linker_histone PF00538.19 OQR94769.1 - 0.082 13.3 0.0 0.34 11.3 0.0 2.1 2 0 0 2 2 2 0 linker histone H1 and H5 family FliL PF03748.14 OQR94769.1 - 0.14 12.7 0.0 0.44 11.2 0.0 1.9 1 0 0 1 1 1 0 Flagellar basal body-associated protein FliL Dpy-30 PF05186.13 OQR94770.1 - 5e-14 51.7 0.0 1.1e-13 50.6 0.0 1.6 1 0 0 1 1 1 1 Dpy-30 motif ADK PF00406.22 OQR94770.1 - 1.9e-07 31.3 0.0 0.00062 19.9 0.0 2.7 1 1 1 2 2 2 2 Adenylate kinase AAA_18 PF13238.6 OQR94770.1 - 0.00025 21.6 0.1 0.014 15.9 0.0 3.0 2 1 0 2 2 2 1 AAA domain APG5 PF04106.12 OQR94784.1 - 1.2e-46 159.2 1.6 1.8e-46 158.6 1.6 1.3 1 0 0 1 1 1 1 Autophagy protein Apg5 Aa_trans PF01490.18 OQR94785.1 - 1.9e-45 155.3 32.0 2.4e-45 155.0 32.0 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Cpn60_TCP1 PF00118.24 OQR94786.1 - 2.1e-91 307.0 13.6 3.5e-91 306.3 13.6 1.3 1 1 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF126 PF01989.16 OQR94786.1 - 0.095 12.5 0.0 1.9 8.4 0.0 2.5 2 0 0 2 2 2 0 Aconitase X swivel domain PH PF00169.29 OQR94787.1 - 7.1e-36 122.9 0.1 7.5e-08 32.8 0.0 9.6 9 0 0 9 9 9 5 PH domain PH_6 PF15406.6 OQR94787.1 - 0.00041 20.6 13.7 0.0051 17.1 0.1 4.8 6 0 0 6 6 6 3 Pleckstrin homology domain PH_11 PF15413.6 OQR94787.1 - 0.24 11.8 19.7 1.5 9.3 0.1 7.4 8 3 1 9 9 9 0 Pleckstrin homology domain PH_13 PF16652.5 OQR94787.1 - 0.34 10.7 2.7 3.2 7.5 0.0 3.6 4 0 0 4 4 4 0 Pleckstrin homology domain ParcG PF10274.9 OQR94788.1 - 3.1e-56 190.4 0.0 5.3e-56 189.6 0.0 1.3 1 0 0 1 1 1 1 Parkin co-regulated protein UQ_con PF00179.26 OQR94789.1 - 3.3e-44 149.9 0.0 4.1e-44 149.6 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UBA PF00627.31 OQR94789.1 - 2.9e-11 43.0 0.0 6.2e-11 42.0 0.0 1.5 1 0 0 1 1 1 1 UBA/TS-N domain Prok-E2_B PF14461.6 OQR94789.1 - 1.7e-06 27.8 0.0 2.2e-06 27.4 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic E2 family B DUF1296 PF06972.11 OQR94789.1 - 0.0023 18.0 0.5 0.016 15.3 0.1 2.5 3 1 1 4 4 4 1 Protein of unknown function (DUF1296) RWD PF05773.22 OQR94789.1 - 0.0034 17.7 0.0 0.0047 17.2 0.0 1.4 1 0 0 1 1 1 1 RWD domain CUE PF02845.16 OQR94789.1 - 0.16 11.7 0.0 0.39 10.5 0.0 1.6 1 0 0 1 1 1 0 CUE domain RIH_assoc PF08454.11 OQR94800.1 - 1.6e-23 82.5 4.4 1.6e-23 82.5 4.4 4.5 4 0 0 4 4 4 1 RyR and IP3R Homology associated Ins145_P3_rec PF08709.11 OQR94800.1 - 2.6e-23 82.3 0.4 3.9e-22 78.5 0.1 2.7 1 1 1 2 2 2 1 Inositol 1,4,5-trisphosphate/ryanodine receptor Ion_trans PF00520.31 OQR94800.1 - 1.1e-11 44.4 7.7 3.1e-11 43.0 7.7 1.7 1 0 0 1 1 1 1 Ion transport protein RYDR_ITPR PF01365.21 OQR94800.1 - 1.3e-11 44.3 18.3 2.3e-07 30.4 1.6 4.3 5 0 0 5 5 5 2 RIH domain MIR PF02815.19 OQR94800.1 - 5e-10 39.5 1.1 0.00012 21.9 0.0 4.2 1 1 2 4 4 4 3 MIR domain L27_N PF09060.10 OQR94800.1 - 0.03 14.4 6.5 0.15 12.1 1.0 3.6 3 0 0 3 3 3 0 L27_N SKA2 PF16740.5 OQR94800.1 - 3.3 7.5 8.9 1 9.2 3.8 3.0 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 2 Glyco_hydro_18 PF00704.28 OQR94801.1 - 1.6e-09 38.0 0.3 1.9e-09 37.7 0.3 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 NhaB PF06450.12 OQR94801.1 - 0.039 12.8 0.1 0.056 12.3 0.1 1.2 1 0 0 1 1 1 0 Bacterial Na+/H+ antiporter B (NhaB) TGS PF02824.21 OQR94803.1 - 0.054 13.6 0.0 0.16 12.0 0.0 1.7 1 1 0 1 1 1 0 TGS domain MOSC_N PF03476.16 OQR94804.1 - 1.3e-43 147.7 0.0 2.7e-32 111.2 0.0 2.5 2 0 0 2 2 2 2 MOSC N-terminal beta barrel domain MOSC PF03473.17 OQR94804.1 - 2.3e-19 69.7 0.0 6.2e-19 68.3 0.0 1.8 2 0 0 2 2 2 1 MOSC domain PDDEXK_10 PF07788.11 OQR94804.1 - 0.026 14.5 0.1 7.2 6.6 0.0 2.8 2 0 0 2 2 2 0 PD-(D/E)XK nuclease superfamily Ank_4 PF13637.6 OQR94805.1 - 3.8e-30 103.9 5.5 0.00011 22.7 0.0 7.7 4 2 3 7 7 7 7 Ankyrin repeats (many copies) Ank_2 PF12796.7 OQR94805.1 - 4.5e-27 94.5 13.9 8e-06 26.4 0.1 5.4 1 1 5 6 6 6 6 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OQR94805.1 - 1.7e-24 85.6 11.5 0.0026 18.0 0.0 11.1 5 3 7 12 12 12 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQR94805.1 - 2.5e-18 64.3 0.6 2.3 9.0 0.0 11.0 11 1 1 12 12 12 3 Ankyrin repeat DUF3447 PF11929.8 OQR94805.1 - 0.0064 16.4 5.4 0.94 9.5 0.2 4.1 1 1 3 4 4 4 2 Domain of unknown function (DUF3447) DUF5049 PF16468.5 OQR94805.1 - 0.016 15.1 12.9 17 5.4 0.0 7.3 4 2 4 8 8 8 0 Domain of unknown function (DUF5049) Ank PF00023.30 OQR94805.1 - 0.044 14.3 1.6 3.4e+02 1.9 0.0 6.5 6 2 0 6 6 6 0 Ankyrin repeat RNase_HII PF01351.18 OQR94806.1 - 8.6e-56 188.9 0.0 1e-55 188.7 0.0 1.1 1 0 0 1 1 1 1 Ribonuclease HII Hydrolase_4 PF12146.8 OQR94807.1 - 2.9e-10 39.8 0.0 6.6e-07 28.8 0.0 2.1 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 OQR94807.1 - 1.9e-06 28.7 0.0 2.8e-06 28.1 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 OQR94807.1 - 7.3e-06 25.8 0.1 2.4e-05 24.1 0.0 1.8 1 1 1 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_2 PF02230.16 OQR94807.1 - 3.1e-05 23.9 0.4 0.0065 16.3 0.0 2.2 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.21 OQR94807.1 - 0.0013 18.3 0.0 0.0021 17.6 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family DUF2920 PF11144.8 OQR94807.1 - 0.027 13.6 0.0 0.094 11.9 0.0 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2920) Ribosomal_L12 PF00542.19 OQR94808.1 - 1.2e-22 80.0 8.9 1.2e-22 80.0 8.9 2.0 2 0 0 2 2 2 1 Ribosomal protein L7/L12 C-terminal domain Ribosomal_L12_N PF16320.5 OQR94808.1 - 3.6e-08 33.0 1.7 3.1e-06 26.8 0.2 2.6 2 0 0 2 2 2 2 Ribosomal protein L7/L12 dimerisation domain HIN PF02760.15 OQR94808.1 - 0.059 13.1 1.0 3.5 7.3 0.0 2.2 2 0 0 2 2 2 0 HIN-200/IF120x domain ENTH PF01417.20 OQR94809.1 - 0.027 14.5 0.5 14 5.8 0.1 3.0 2 1 0 2 2 2 0 ENTH domain AP4E_app_platf PF14807.6 OQR94809.1 - 0.041 14.2 0.0 5.7 7.4 0.0 2.5 2 0 0 2 2 2 0 Adaptin AP4 complex epsilon appendage platform DUF333 PF03891.15 OQR94809.1 - 0.041 14.1 0.6 11 6.3 0.0 3.5 4 0 0 4 4 4 0 Domain of unknown function (DUF333) LVIVD PF08309.11 OQR94809.1 - 0.046 13.0 1.7 0.15 11.4 0.2 2.3 2 0 0 2 2 2 0 LVIVD repeat Marek_SORF3 PF07153.11 OQR94809.1 - 0.36 10.1 5.4 11 5.3 0.3 3.4 3 0 0 3 3 3 0 Marek's disease-like virus SORF3 protein CUTL PF16557.5 OQR94809.1 - 0.99 9.6 4.6 22 5.3 0.5 2.8 2 0 0 2 2 2 0 CUT1-like DNA-binding domain of SATB Prefoldin PF02996.17 OQR94810.1 - 0.03 14.2 3.0 0.055 13.4 1.6 2.2 2 0 0 2 2 2 0 Prefoldin subunit RNase_P_Rpp14 PF01900.19 OQR94811.1 - 1.5e-05 25.2 0.0 1.9e-05 24.9 0.0 1.1 1 0 0 1 1 1 1 Rpp14/Pop5 family VWA_2 PF13519.6 OQR94812.1 - 4e-11 43.5 0.1 9.2e-11 42.3 0.1 1.7 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.28 OQR94812.1 - 0.0022 18.3 0.0 0.0044 17.3 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain INT_SG_DDX_CT_C PF15300.6 OQR94812.1 - 0.0041 16.9 0.0 0.0091 15.8 0.0 1.6 1 0 0 1 1 1 1 INTS6/SAGE1/DDX26B/CT45 C-terminus TPR_2 PF07719.17 OQR94813.1 - 3.5e-19 67.3 17.1 0.0025 17.8 0.0 9.1 9 0 0 9 9 9 5 Tetratricopeptide repeat TPR_1 PF00515.28 OQR94813.1 - 1.6e-17 62.5 12.2 6.6e-05 22.6 0.0 7.8 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_8 PF13181.6 OQR94813.1 - 1.2e-16 59.4 8.7 0.044 14.0 0.0 7.6 8 0 0 8 8 7 4 Tetratricopeptide repeat TPR_19 PF14559.6 OQR94813.1 - 1.5e-16 60.7 10.6 0.00017 22.0 0.0 6.8 6 1 1 7 7 7 4 Tetratricopeptide repeat TPR_16 PF13432.6 OQR94813.1 - 1.8e-12 47.7 11.6 7e-06 26.6 0.0 6.5 5 2 1 6 6 6 2 Tetratricopeptide repeat TPR_14 PF13428.6 OQR94813.1 - 4.3e-12 45.8 16.9 0.07 14.0 0.0 9.3 4 2 7 11 11 11 4 Tetratricopeptide repeat TPR_11 PF13414.6 OQR94813.1 - 1.3e-09 37.6 3.8 0.078 12.7 0.0 6.6 6 2 2 8 8 8 4 TPR repeat TPR_9 PF13371.6 OQR94813.1 - 5.9e-09 36.0 6.1 0.061 13.5 0.0 5.5 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_6 PF13174.6 OQR94813.1 - 1.1e-08 35.2 4.1 3.6 8.4 0.2 7.7 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_7 PF13176.6 OQR94813.1 - 6.1e-08 32.1 11.5 1.8 8.8 0.0 7.4 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_17 PF13431.6 OQR94813.1 - 6.4e-08 32.5 2.9 0.2 12.1 0.0 7.0 8 0 0 8 8 6 1 Tetratricopeptide repeat TPR_21 PF09976.9 OQR94813.1 - 2e-07 30.9 0.6 0.0018 18.0 0.1 4.0 3 2 0 3 3 3 2 Tetratricopeptide repeat-like domain TPR_15 PF13429.6 OQR94813.1 - 2e-05 23.9 11.1 0.0077 15.5 0.1 4.3 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 OQR94813.1 - 4.9e-05 23.5 21.0 0.28 11.5 0.0 7.5 7 2 1 8 8 8 2 Tetratricopeptide repeat TPR_20 PF14561.6 OQR94813.1 - 0.0074 16.6 0.3 0.048 14.0 0.0 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat ANAPC3 PF12895.7 OQR94813.1 - 0.01 16.0 14.9 9.6 6.5 1.7 5.5 3 2 2 5 5 5 0 Anaphase-promoting complex, cyclosome, subunit 3 DSPc PF00782.20 OQR94814.1 - 1.1e-09 38.2 0.0 2.9e-09 36.8 0.0 1.7 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 OQR94814.1 - 7e-08 32.3 0.0 1.2e-07 31.6 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase CDKN3 PF05706.12 OQR94814.1 - 0.00059 19.5 0.0 0.00095 18.9 0.0 1.3 1 0 0 1 1 1 1 Cyclin-dependent kinase inhibitor 3 (CDKN3) Y_phosphatase3 PF13350.6 OQR94814.1 - 0.0071 16.3 0.0 0.012 15.6 0.0 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase2 PF03162.13 OQR94814.1 - 0.053 13.1 0.0 0.51 9.9 0.0 2.1 2 0 0 2 2 2 0 Tyrosine phosphatase family Integrase_Zn PF02022.19 OQR94814.1 - 0.37 10.8 1.5 0.69 9.9 0.1 2.1 2 0 0 2 2 2 0 Integrase Zinc binding domain Pkinase_Tyr PF07714.17 OQR94815.1 - 2.5e-60 204.0 0.0 3.3e-60 203.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OQR94815.1 - 3.1e-60 203.8 0.0 5e-60 203.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 OQR94815.1 - 0.001 18.0 0.0 0.0021 16.9 0.0 1.5 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 OQR94815.1 - 0.054 12.4 0.1 0.11 11.5 0.1 1.4 1 0 0 1 1 1 0 Haspin like kinase domain ACT PF01842.25 OQR94815.1 - 0.12 12.2 0.1 0.24 11.2 0.1 1.5 1 0 0 1 1 1 0 ACT domain APH PF01636.23 OQR94815.1 - 0.2 11.6 0.0 0.2 11.6 0.0 2.1 3 0 0 3 3 3 0 Phosphotransferase enzyme family MFAP1 PF06991.11 OQR94815.1 - 1.3 8.8 5.1 2.4 7.9 5.1 1.3 1 0 0 1 1 1 0 Microfibril-associated/Pre-mRNA processing DUF2046 PF09755.9 OQR94817.1 - 8.9e-08 31.7 19.1 0.0015 17.8 2.9 3.0 1 1 1 2 2 2 2 Uncharacterized conserved protein H4 (DUF2046) Diphthami_syn_2 PF01902.17 OQR94817.1 - 0.0004 19.9 1.2 0.00064 19.3 1.2 1.4 1 1 0 1 1 1 1 Diphthamide synthase AAA_18 PF13238.6 OQR94817.1 - 0.27 11.8 3.6 0.37 11.3 3.1 1.5 1 1 0 1 1 1 0 AAA domain Sigma54_CBD PF04963.13 OQR94817.1 - 0.94 9.3 8.7 10 5.9 8.7 2.4 1 1 0 1 1 1 0 Sigma-54 factor, core binding domain ApoO PF09769.9 OQR94817.1 - 1.2 9.1 4.7 10 6.1 0.5 2.6 2 1 1 3 3 3 0 Apolipoprotein O zf-CRD PF17979.1 OQR94817.1 - 1.7 8.7 5.1 1.1 9.3 1.6 2.0 1 1 1 2 2 2 0 Cysteine rich domain with multizinc binding regions Mic1 PF07035.12 OQR94818.1 - 1.7e-07 31.1 2.5 4.7e-07 29.6 2.5 1.7 1 0 0 1 1 1 1 Colon cancer-associated protein Mic1-like Ank_2 PF12796.7 OQR94819.1 - 7.4e-26 90.6 3.8 1e-10 42.0 0.1 3.3 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.30 OQR94819.1 - 1.8e-25 88.2 11.5 4.9e-06 26.8 0.1 6.1 6 0 0 6 6 6 6 Ankyrin repeat Ank_4 PF13637.6 OQR94819.1 - 3.1e-24 85.0 4.2 8.6e-08 32.6 0.0 4.1 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQR94819.1 - 2.9e-22 76.4 3.9 0.0012 19.1 0.0 6.1 6 0 0 6 6 6 5 Ankyrin repeat Ank_5 PF13857.6 OQR94819.1 - 1.1e-19 70.2 4.5 1.2e-08 35.0 0.2 3.9 2 1 3 5 5 5 3 Ankyrin repeats (many copies) MetallophosN PF16371.5 OQR94819.1 - 2.5e-07 30.9 0.1 0.12 12.7 0.0 3.3 3 0 0 3 3 3 3 N terminal of Calcineurin-like phosphoesterase Amidohydro_1 PF01979.20 OQR94820.1 - 1.6e-32 113.2 0.0 2.4e-32 112.6 0.0 1.2 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 OQR94820.1 - 6.7e-06 25.8 0.0 8.6e-06 25.5 0.0 1.2 1 0 0 1 1 1 1 Amidohydrolase family LRR_4 PF12799.7 OQR94822.1 - 8.2e-11 42.0 8.8 0.0015 18.9 0.5 5.2 3 2 4 7 7 7 4 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 OQR94822.1 - 3e-06 26.9 16.2 0.64 10.2 0.0 7.9 10 0 0 10 10 10 3 Leucine Rich repeat LRR_8 PF13855.6 OQR94822.1 - 0.0011 18.7 11.5 0.0014 18.3 1.4 4.2 3 2 1 4 4 4 1 Leucine rich repeat LRR_1 PF00560.33 OQR94822.1 - 0.63 10.8 15.3 35 5.5 0.0 7.0 9 0 0 9 9 9 0 Leucine Rich Repeat SAM_Ste50p PF09235.10 OQR94822.1 - 0.9 9.8 5.0 11 6.4 0.1 3.6 3 1 1 4 4 4 0 Ste50p, sterile alpha motif DnaJ PF00226.31 OQR94871.1 - 3.4e-18 65.5 0.2 9.7e-18 64.1 0.2 1.8 1 0 0 1 1 1 1 DnaJ domain Atg14 PF10186.9 OQR94871.1 - 2 7.4 10.6 4.5 6.3 10.6 1.5 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 PP2C PF00481.21 OQR94872.1 - 3.4e-48 164.5 0.2 5.8e-48 163.8 0.2 1.4 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 OQR94872.1 - 5.5e-07 29.4 0.0 1.7e-06 27.9 0.0 1.7 1 1 0 1 1 1 1 Protein phosphatase 2C HrpJ PF07201.11 OQR94872.1 - 0.0025 18.2 0.5 0.093 13.0 0.0 2.7 3 0 0 3 3 3 1 HrpJ-like domain SpoIIE PF07228.12 OQR94872.1 - 0.012 15.5 0.1 0.035 14.0 0.0 1.8 2 0 0 2 2 2 0 Stage II sporulation protein E (SpoIIE) Tnp_22_dsRBD PF17490.2 OQR94872.1 - 0.17 11.9 0.1 0.53 10.3 0.0 1.8 2 0 0 2 2 2 0 L1 transposable element dsRBD-like domain HBS1_N PF08938.10 OQR94872.1 - 0.42 10.9 1.8 1.5 9.1 0.2 2.3 2 1 0 2 2 2 0 HBS1 N-terminus zf-C3HC4_3 PF13920.6 OQR94873.1 - 1.2e-06 28.3 11.4 1.2e-06 28.3 11.4 3.4 4 1 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) R3H PF01424.22 OQR94873.1 - 0.00049 20.0 0.8 0.0011 18.9 0.8 1.7 1 0 0 1 1 1 1 R3H domain Prok-RING_4 PF14447.6 OQR94873.1 - 0.0028 17.5 7.6 0.0028 17.5 7.6 2.9 4 0 0 4 4 4 1 Prokaryotic RING finger family 4 tRNA_synt_1c_R2 PF04557.15 OQR94873.1 - 0.024 15.6 0.7 0.059 14.3 0.7 1.7 1 0 0 1 1 1 0 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 2 MbeD_MobD PF04899.12 OQR94873.1 - 0.038 14.1 0.8 0.12 12.6 0.8 1.9 1 0 0 1 1 1 0 MbeD/MobD like GAIN_A PF18619.1 OQR94873.1 - 0.13 12.5 0.3 1.7 8.9 0.1 2.5 2 0 0 2 2 2 0 GPCR-Autoproteolysis-INducing (GAIN) subdomain A zf_Hakai PF18408.1 OQR94873.1 - 0.39 10.5 4.2 0.37 10.5 0.5 2.6 2 0 0 2 2 2 0 C2H2 Hakai zinc finger domain E2F_TDP PF02319.20 OQR94874.1 - 1.6e-37 127.3 2.9 1.8e-19 69.6 0.3 2.8 3 0 0 3 3 3 2 E2F/DP family winged-helix DNA-binding domain TrmB PF01978.19 OQR94874.1 - 0.0068 16.3 0.1 0.2 11.6 0.0 2.3 2 0 0 2 2 2 1 Sugar-specific transcriptional regulator TrmB Cdc6_C PF09079.11 OQR94874.1 - 0.32 11.0 2.2 2 8.5 0.0 2.8 3 0 0 3 3 3 0 CDC6, C terminal winged helix domain SUV3_C PF12513.8 OQR94875.1 - 5.4e-14 51.9 0.2 1.6e-13 50.3 0.2 1.9 1 0 0 1 1 1 1 Mitochondrial degradasome RNA helicase subunit C terminal Suv3_C_1 PF18147.1 OQR94875.1 - 4.8e-12 45.6 0.0 1.2e-11 44.2 0.0 1.8 1 0 0 1 1 1 1 Suv3 C-terminal domain 1 Helicase_C PF00271.31 OQR94875.1 - 3.6e-10 40.2 0.0 7.1e-10 39.2 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Suv3_N PF18114.1 OQR94875.1 - 0.025 14.7 0.0 0.053 13.6 0.0 1.5 1 0 0 1 1 1 0 Suv3 helical N-terminal domain RepA_C PF04796.12 OQR94875.1 - 0.034 14.2 0.0 0.068 13.2 0.0 1.4 1 0 0 1 1 1 0 Plasmid encoded RepA protein CRT-like PF08627.10 OQR94876.1 - 2e-117 391.9 21.4 2.3e-117 391.7 21.4 1.0 1 0 0 1 1 1 1 CRT-like, chloroquine-resistance transporter-like UAA PF08449.11 OQR94876.1 - 3.3e-06 26.5 17.3 0.00013 21.3 17.9 2.4 1 1 0 1 1 1 1 UAA transporter family SLC35F PF06027.12 OQR94876.1 - 2.3e-05 24.1 6.4 2.3e-05 24.1 6.4 2.1 2 0 0 2 2 2 2 Solute carrier family 35 EamA PF00892.20 OQR94876.1 - 0.14 12.3 30.1 0.34 11.1 2.2 3.3 3 1 0 3 3 3 0 EamA-like transporter family Pkinase PF00069.25 OQR94877.1 - 1.8e-61 207.8 0.0 3e-61 207.1 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQR94877.1 - 8.3e-31 107.2 0.0 1.2e-30 106.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OQR94877.1 - 3.1e-05 23.5 0.0 4.5e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 OQR94877.1 - 0.00018 20.6 0.3 0.00034 19.7 0.3 1.4 1 1 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 OQR94877.1 - 0.0029 17.6 0.2 0.0059 16.6 0.2 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 OQR94877.1 - 0.016 14.6 0.8 0.025 13.9 0.8 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.9 OQR94877.1 - 0.033 13.7 0.0 0.066 12.7 0.0 1.4 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL RIO1 PF01163.22 OQR94877.1 - 0.052 13.1 0.0 0.096 12.3 0.0 1.4 1 0 0 1 1 1 0 RIO1 family Pkinase_fungal PF17667.1 OQR94877.1 - 0.12 11.1 0.3 0.14 10.9 0.3 1.3 1 1 0 1 1 1 0 Fungal protein kinase Seadorna_VP7 PF07387.11 OQR94877.1 - 0.22 10.6 0.1 0.36 9.9 0.1 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Rad17 PF03215.15 OQR94878.1 - 3.9e-22 79.1 0.2 1.4e-21 77.3 0.2 1.9 1 0 0 1 1 1 1 Rad17 P-loop domain zf-RanBP PF00641.18 OQR94878.1 - 1.7e-07 30.4 17.1 0.0013 18.0 5.1 2.5 2 0 0 2 2 2 2 Zn-finger in Ran binding protein and others AAA_16 PF13191.6 OQR94878.1 - 5.8e-05 23.5 0.0 0.00016 22.1 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 OQR94878.1 - 5.8e-05 22.7 0.0 0.00024 20.8 0.0 1.9 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_22 PF13401.6 OQR94878.1 - 0.00011 22.5 0.0 0.00035 20.8 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 OQR94878.1 - 0.00027 21.4 0.0 0.00096 19.6 0.0 2.0 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 OQR94878.1 - 0.00033 21.2 0.3 0.0013 19.3 0.0 2.2 2 0 0 2 2 1 1 AAA domain AAA_assoc_2 PF16193.5 OQR94878.1 - 0.0006 20.1 0.0 0.0022 18.3 0.0 2.0 1 0 0 1 1 1 1 AAA C-terminal domain AAA_33 PF13671.6 OQR94878.1 - 0.0041 17.3 0.7 0.01 16.0 0.1 2.0 2 0 0 2 2 1 1 AAA domain AAA_5 PF07728.14 OQR94878.1 - 0.0044 17.0 0.0 0.015 15.3 0.0 2.0 2 0 0 2 2 1 1 AAA domain (dynein-related subfamily) NTPase_1 PF03266.15 OQR94878.1 - 0.0052 16.7 0.0 0.014 15.3 0.0 1.7 1 0 0 1 1 1 1 NTPase RsgA_GTPase PF03193.16 OQR94878.1 - 0.0085 16.0 0.0 0.021 14.7 0.0 1.6 1 0 0 1 1 1 1 RsgA GTPase RNA_helicase PF00910.22 OQR94878.1 - 0.0097 16.3 0.3 0.029 14.7 0.0 2.1 2 0 0 2 2 1 1 RNA helicase RuvB_N PF05496.12 OQR94878.1 - 0.01 15.6 0.0 0.036 13.8 0.0 1.9 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain ArsA_ATPase PF02374.15 OQR94878.1 - 0.012 14.8 1.2 4.9 6.2 0.6 2.7 2 0 0 2 2 2 0 Anion-transporting ATPase NB-ARC PF00931.22 OQR94878.1 - 0.012 14.8 0.0 0.028 13.6 0.0 1.7 1 0 0 1 1 1 0 NB-ARC domain DNA_pol3_delta PF06144.13 OQR94878.1 - 0.017 14.9 0.2 0.059 13.1 0.2 1.9 1 0 0 1 1 1 0 DNA polymerase III, delta subunit AAA_PrkA PF08298.11 OQR94878.1 - 0.019 13.9 0.0 0.035 13.0 0.0 1.3 1 0 0 1 1 1 0 PrkA AAA domain DUF1462 PF07315.11 OQR94878.1 - 0.071 13.4 0.1 16 5.8 0.0 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1462) Sec5 PF15469.6 OQR94878.1 - 0.081 12.7 2.3 0.64 9.8 0.4 2.6 2 0 0 2 2 2 0 Exocyst complex component Sec5 TsaE PF02367.17 OQR94878.1 - 0.088 12.8 0.0 0.48 10.4 0.0 2.2 1 1 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_17 PF13207.6 OQR94878.1 - 0.13 12.7 0.3 0.98 9.8 0.2 2.6 2 0 0 2 2 2 0 AAA domain Ploopntkinase3 PF18751.1 OQR94878.1 - 0.13 12.1 0.0 0.26 11.2 0.0 1.4 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 RecR PF02132.15 OQR94878.1 - 7.5 6.2 19.2 0.86 9.2 1.5 3.1 3 0 0 3 3 2 0 RecR protein Acyltransferase PF01553.21 OQR94879.1 - 1.3e-19 70.1 0.0 2.6e-19 69.2 0.0 1.5 1 0 0 1 1 1 1 Acyltransferase Acyltransf_C PF16076.5 OQR94879.1 - 1.7e-12 47.2 0.0 3.2e-12 46.3 0.0 1.5 1 0 0 1 1 1 1 Acyltransferase C-terminus F-protein PF00469.20 OQR94880.1 - 0.14 11.8 0.0 0.2 11.2 0.0 1.2 1 0 0 1 1 1 0 Negative factor, (F-Protein) or Nef TPR_14 PF13428.6 OQR94881.1 - 0.0068 17.1 0.1 5.6 8.1 0.1 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 OQR94881.1 - 0.0074 16.4 0.2 3.2 8.2 0.1 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.6 OQR94881.1 - 0.011 16.1 0.4 0.2 12.0 0.3 2.4 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.17 OQR94881.1 - 0.011 15.8 0.1 1 9.6 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.28 OQR94881.1 - 0.044 13.6 0.0 1.9 8.5 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat WW PF00397.26 OQR94881.1 - 0.051 13.7 0.6 0.051 13.7 0.6 1.9 2 0 0 2 2 2 0 WW domain FMN_red PF03358.15 OQR94904.1 - 2.2e-05 24.3 0.2 3.2e-05 23.7 0.2 1.3 1 0 0 1 1 1 1 NADPH-dependent FMN reductase DNase_II PF03265.15 OQR94904.1 - 0.074 12.3 0.0 0.098 11.9 0.0 1.2 1 0 0 1 1 1 0 Deoxyribonuclease II Flavodoxin_2 PF02525.17 OQR94904.1 - 0.091 12.5 0.1 0.14 11.8 0.1 1.3 1 0 0 1 1 1 0 Flavodoxin-like fold START PF01852.19 OQR94905.1 - 3e-05 23.5 0.1 0.00019 20.9 0.0 2.4 3 0 0 3 3 3 1 START domain PDZ_6 PF17820.1 OQR94905.1 - 0.001 18.9 0.1 0.44 10.4 0.0 2.7 2 0 0 2 2 2 2 PDZ domain PDZ PF00595.24 OQR94905.1 - 0.022 15.1 0.1 0.49 10.8 0.1 2.3 2 0 0 2 2 2 0 PDZ domain Tricorn_PDZ PF14685.6 OQR94905.1 - 0.13 12.3 0.0 3.4 7.7 0.0 2.4 2 0 0 2 2 2 0 Tricorn protease PDZ domain CBM9_2 PF16011.5 OQR94906.1 - 0.00035 20.4 1.1 0.00057 19.6 1.1 1.3 1 1 0 1 1 1 1 Carbohydrate-binding family 9 PQ-loop PF04193.14 OQR94907.1 - 1.9e-33 114.0 25.8 3.8e-19 68.2 7.8 3.4 4 0 0 4 4 4 2 PQ loop repeat Yip1 PF04893.17 OQR94915.1 - 7.6e-05 22.5 1.5 8.5e-05 22.3 1.5 1.0 1 0 0 1 1 1 1 Yip1 domain SPRY PF00622.28 OQR94916.1 - 1.1e-05 25.5 0.1 2.2e-05 24.5 0.1 1.7 1 1 0 1 1 1 1 SPRY domain Neuralized PF07177.12 OQR94916.1 - 0.0021 18.1 0.0 0.0042 17.1 0.0 1.5 1 0 0 1 1 1 1 Neuralized FH2 PF02181.23 OQR94916.1 - 0.0091 15.2 5.6 0.013 14.6 5.6 1.2 1 0 0 1 1 1 1 Formin Homology 2 Domain TMP_2 PF06791.13 OQR94916.1 - 0.04 13.6 0.2 0.064 12.9 0.2 1.3 1 0 0 1 1 1 0 Prophage tail length tape measure protein HAP1_N PF04849.13 OQR94916.1 - 0.1 11.8 9.9 0.14 11.3 9.9 1.1 1 0 0 1 1 1 0 HAP1 N-terminal conserved region UPF0242 PF06785.11 OQR94916.1 - 0.19 11.8 11.2 0.3 11.2 11.2 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus LCIB_C_CA PF18599.1 OQR94916.1 - 0.33 10.2 3.1 0.55 9.5 3.1 1.4 1 0 0 1 1 1 0 Limiting CO2-inducible proteins B/C beta carbonyic anhydrases Cortex-I_coil PF09304.10 OQR94916.1 - 0.37 11.0 8.2 1.1 9.4 2.9 2.2 1 1 1 2 2 2 0 Cortexillin I, coiled coil RRM_1 PF00076.22 OQR94918.1 - 2.3e-27 94.6 0.1 3.1e-13 49.3 0.0 2.7 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Cnd1 PF12717.7 OQR94918.1 - 3.1e-21 76.1 11.1 7.4e-17 61.9 0.4 5.4 5 1 0 5 5 5 3 non-SMC mitotic condensation complex subunit 1 UBA PF00627.31 OQR94918.1 - 1.5e-16 59.9 0.6 1.7e-09 37.4 0.1 3.0 2 0 0 2 2 2 2 UBA/TS-N domain G-patch PF01585.23 OQR94918.1 - 6e-11 42.1 6.3 1.3e-10 41.0 6.3 1.5 1 0 0 1 1 1 1 G-patch domain OCRE PF17780.1 OQR94918.1 - 3.6e-09 36.5 11.2 6.8e-09 35.6 11.2 1.4 1 0 0 1 1 1 1 OCRE domain Cnd3 PF12719.7 OQR94918.1 - 5.2e-06 25.9 5.5 1.5e-05 24.4 0.4 3.7 4 0 0 4 4 4 1 Nuclear condensing complex subunits, C-term domain zf-RanBP PF00641.18 OQR94918.1 - 0.00014 21.1 3.9 0.00034 19.9 3.9 1.6 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others HEAT PF02985.22 OQR94918.1 - 0.0002 21.3 10.7 6.4 7.3 0.1 7.3 7 0 0 7 7 7 1 HEAT repeat Cohesin_HEAT PF12765.7 OQR94918.1 - 0.0092 16.3 0.2 23 5.4 0.0 3.9 3 0 0 3 3 3 0 HEAT repeat associated with sister chromatid cohesion G-patch_2 PF12656.7 OQR94918.1 - 0.012 15.6 2.6 0.032 14.3 2.6 1.7 1 0 0 1 1 1 0 G-patch domain zf-C2H2_11 PF16622.5 OQR94918.1 - 0.013 15.3 0.5 0.04 13.7 0.5 1.9 1 0 0 1 1 1 0 zinc-finger C2H2-type HEAT_2 PF13646.6 OQR94918.1 - 0.015 15.7 1.3 12 6.3 0.0 3.8 3 0 0 3 3 3 0 HEAT repeats zf-C2H2_jaz PF12171.8 OQR94918.1 - 0.031 14.6 0.1 0.11 12.8 0.1 2.0 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 OQR94918.1 - 0.19 12.2 2.8 0.41 11.1 0.1 2.6 2 0 0 2 2 2 0 Zinc-finger of C2H2 type SPRY PF00622.28 OQR94919.1 - 4.7e-08 33.2 0.0 8.3e-08 32.4 0.0 1.4 1 0 0 1 1 1 1 SPRY domain Neuralized PF07177.12 OQR94919.1 - 0.00065 19.7 0.0 0.0012 18.8 0.0 1.5 1 0 0 1 1 1 1 Neuralized TPR_MLP1_2 PF07926.12 OQR94919.1 - 0.0052 16.8 13.4 0.0081 16.2 13.4 1.2 1 0 0 1 1 1 1 TPR/MLP1/MLP2-like protein Exonuc_VII_L PF02601.15 OQR94919.1 - 0.035 13.7 2.0 0.044 13.3 2.0 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit FAM76 PF16046.5 OQR94919.1 - 0.069 12.5 5.1 0.11 11.8 5.1 1.2 1 0 0 1 1 1 0 FAM76 protein IZUMO PF15005.6 OQR94919.1 - 0.26 11.8 3.4 0.53 10.8 3.4 1.4 1 0 0 1 1 1 0 Izumo sperm-egg fusion, Ig domain-associated K-box PF01486.17 OQR94919.1 - 0.59 10.3 14.3 48 4.2 14.3 2.4 1 1 0 1 1 1 0 K-box region Tweety PF04906.13 OQR94919.1 - 0.8 8.3 4.5 1.1 7.8 4.5 1.1 1 0 0 1 1 1 0 Tweety DUF1904 PF08921.11 OQR94920.1 - 0.03 14.6 0.1 0.056 13.8 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1904) IBR PF01485.21 OQR94946.1 - 4.8e-07 29.9 10.1 4.8e-07 29.9 10.1 3.6 2 1 2 4 4 4 2 IBR domain, a half RING-finger domain zf-C3HC4 PF00097.25 OQR94946.1 - 0.00012 21.9 8.4 0.00012 21.9 8.4 3.3 2 2 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OQR94946.1 - 0.00045 20.2 3.8 0.00045 20.2 3.8 2.9 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 OQR94946.1 - 0.0044 16.8 0.2 0.0044 16.8 0.2 4.5 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 OQR94946.1 - 0.019 15.3 11.3 0.019 15.3 11.3 3.7 2 2 1 3 3 3 0 Ring finger domain zf-RING_5 PF14634.6 OQR94946.1 - 0.022 14.7 10.0 0.022 14.7 10.0 2.7 2 1 0 2 2 2 0 zinc-RING finger domain XFP PF03894.15 OQR94946.1 - 0.065 13.0 0.0 0.12 12.0 0.0 1.4 1 1 0 1 1 1 0 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase Zn_Tnp_IS91 PF14319.6 OQR94946.1 - 0.52 10.4 13.4 1.3 9.1 0.5 2.4 2 0 0 2 2 2 0 Transposase zinc-binding domain zf-RING_14 PF17978.1 OQR94946.1 - 0.86 10.1 11.4 0.44 11.0 3.1 2.5 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain Glyco_hydro_12 PF01670.16 OQR94954.1 - 2.3e-43 148.7 8.3 2.6e-43 148.5 8.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 12 Glyco_hydro_53 PF07745.13 OQR94955.1 - 0.082 11.9 0.0 0.18 10.7 0.0 1.6 1 1 0 1 1 1 0 Glycosyl hydrolase family 53 MFS_1 PF07690.16 OQR94956.1 - 9.2e-22 77.4 34.7 1.3e-21 76.9 34.7 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily SPX PF03105.19 OQR94956.1 - 1.1e-15 58.5 18.2 2.4e-08 34.3 1.2 3.2 2 1 1 3 3 3 3 SPX domain OATP PF03137.20 OQR94956.1 - 5.9e-05 21.6 1.9 5.9e-05 21.6 1.9 1.6 1 1 1 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family CCDC154 PF15450.6 OQR94956.1 - 0.021 13.4 2.3 0.036 12.6 2.3 1.3 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 154 Sugar_tr PF00083.24 OQR94956.1 - 0.094 11.6 23.2 1.3 7.8 23.2 2.2 1 1 0 1 1 1 0 Sugar (and other) transporter hDGE_amylase PF14701.6 OQR94956.1 - 0.16 11.0 1.0 0.25 10.4 1.0 1.2 1 0 0 1 1 1 0 Glycogen debranching enzyme, glucanotransferase domain Glyco_hydro_28 PF00295.17 OQR94957.1 - 3.8e-107 358.1 18.0 4.3e-107 357.9 18.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Rhamnogal_lyase PF06045.11 OQR94957.1 - 0.16 11.3 0.9 0.27 10.6 0.9 1.2 1 0 0 1 1 1 0 Rhamnogalacturonate lyase family NT5C PF06941.12 OQR94963.1 - 0.0066 16.3 0.2 0.012 15.5 0.2 1.4 1 1 0 1 1 1 1 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C) eIF-1a PF01176.19 OQR94965.1 - 6.1e-21 74.0 0.2 8.8e-21 73.5 0.2 1.3 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 ADH_zinc_N PF00107.26 OQR94968.1 - 3.6e-12 46.4 0.1 1.3e-11 44.6 0.0 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 OQR94968.1 - 0.0017 18.2 0.0 0.57 10.1 0.0 2.3 1 1 1 2 2 2 2 Alcohol dehydrogenase GroES-like domain ADH_N_2 PF16884.5 OQR94968.1 - 0.0045 16.9 0.0 0.0076 16.1 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase NAD_binding_10 PF13460.6 OQR94968.1 - 0.0048 16.8 0.1 0.0079 16.1 0.1 1.3 1 0 0 1 1 1 1 NAD(P)H-binding TrkA_N PF02254.18 OQR94968.1 - 0.023 14.9 0.2 0.039 14.2 0.2 1.3 1 0 0 1 1 1 0 TrkA-N domain SGTA_dimer PF16546.5 OQR94975.1 - 0.0016 18.1 0.3 0.0035 17.1 0.3 1.6 1 0 0 1 1 1 1 Homodimerisation domain of SGTA UPF0004 PF00919.20 OQR94975.1 - 0.066 13.3 0.1 0.088 12.9 0.1 1.2 1 0 0 1 1 1 0 Uncharacterized protein family UPF0004 Tnp_zf-ribbon_2 PF13842.6 OQR94976.1 - 1.9e-05 25.4 8.3 1.9e-05 25.4 8.3 2.3 3 0 0 3 3 3 1 DDE_Tnp_1-like zinc-ribbon zf-RanBP PF00641.18 OQR94976.1 - 6e-05 22.3 3.0 0.00017 20.8 3.0 1.9 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others Elicitin PF00964.17 OQR94977.1 - 1.8e-05 24.8 0.2 2.3e-05 24.4 0.2 1.3 1 0 0 1 1 1 1 Elicitin Cupin_5 PF06172.11 OQR94978.1 - 3.1e-28 98.7 0.0 3.6e-28 98.5 0.0 1.1 1 0 0 1 1 1 1 Cupin superfamily (DUF985) Elicitin PF00964.17 OQR94979.1 - 0.0081 16.2 9.7 0.81 9.8 1.8 3.4 2 1 0 2 2 2 2 Elicitin Unpaired PF15972.5 OQR94979.1 - 0.15 11.6 0.0 1.4 8.4 0.0 2.1 2 0 0 2 2 2 0 Unpaired protein DUF4690 PF15756.5 OQR94979.1 - 2 9.1 11.9 0.42 11.2 4.4 2.4 2 0 0 2 2 2 0 Small Novel Rich in Cartilage Elicitin PF00964.17 OQR94980.1 - 0.0022 18.0 0.1 0.0031 17.6 0.1 1.2 1 0 0 1 1 1 1 Elicitin DUF1664 PF07889.12 OQR94981.1 - 0.0035 17.4 1.7 0.0041 17.2 1.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1664) Laminin_II PF06009.12 OQR94981.1 - 0.013 15.5 1.9 0.015 15.3 1.9 1.1 1 0 0 1 1 1 0 Laminin Domain II GP41 PF00517.17 OQR94981.1 - 0.033 14.1 0.8 0.04 13.8 0.8 1.1 1 0 0 1 1 1 0 Retroviral envelope protein Herpes_UL25 PF01499.16 OQR94981.1 - 0.051 12.1 1.9 0.052 12.1 1.9 1.0 1 0 0 1 1 1 0 Herpesvirus UL25 family NPV_P10 PF05531.12 OQR94981.1 - 0.08 13.4 2.0 0.12 12.8 2.0 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein Elicitin PF00964.17 OQR94982.1 - 2e-05 24.6 1.3 2.9e-05 24.1 1.0 1.4 1 1 0 1 1 1 1 Elicitin Elicitin PF00964.17 OQR94983.1 - 1.4e-08 34.7 0.7 2.1e-08 34.1 0.7 1.2 1 0 0 1 1 1 1 Elicitin DUF5004 PF16395.5 OQR94983.1 - 0.064 13.3 0.1 0.089 12.8 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5004) DUF2475 PF10629.9 OQR94984.1 - 0.043 14.0 0.0 0.06 13.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2475) TRAM_LAG1_CLN8 PF03798.16 OQR94985.1 - 4.1e-28 98.5 61.9 1.9e-15 57.1 17.9 4.0 3 1 1 4 4 4 3 TLC domain Glutaminase PF04960.15 OQR94988.1 - 2.1e-114 381.5 3.6 2.9e-89 299.1 0.0 2.7 3 0 0 3 3 3 2 Glutaminase Ank_2 PF12796.7 OQR94988.1 - 3.5e-25 88.4 0.1 4.5e-11 43.2 0.0 3.6 3 1 0 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQR94988.1 - 1e-20 73.8 4.0 2e-06 28.2 0.1 4.2 2 2 3 5 5 5 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 OQR94988.1 - 8.8e-16 57.8 0.8 2.8e-06 27.5 0.0 3.7 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQR94988.1 - 5.5e-14 50.9 0.8 0.0033 17.8 0.0 6.1 6 0 0 6 6 6 2 Ankyrin repeat Ank PF00023.30 OQR94988.1 - 5.9e-12 45.5 2.6 0.0035 17.7 0.0 5.9 6 1 0 6 6 6 2 Ankyrin repeat EF-hand_14 PF17959.1 OQR94988.1 - 1.7e-09 37.9 0.0 4.8e-09 36.5 0.0 1.8 1 0 0 1 1 1 1 EF-hand domain DUF1843 PF08898.10 OQR94988.1 - 0.00021 21.7 0.3 2.5 8.7 0.1 3.7 4 0 0 4 4 4 2 Domain of unknown function (DUF1843) TetR PF13972.6 OQR94988.1 - 0.064 13.0 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 Bacterial transcriptional repressor MCM PF00493.23 OQR95013.1 - 2e-98 328.0 0.2 3.1e-98 327.4 0.2 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 OQR95013.1 - 9e-37 125.7 0.9 2e-36 124.6 0.9 1.5 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 OQR95013.1 - 3.6e-27 94.6 3.1 7.4e-27 93.6 0.8 2.5 2 0 0 2 2 2 1 MCM AAA-lid domain MCM_N PF14551.6 OQR95013.1 - 1.9e-11 44.5 0.0 6.9e-11 42.7 0.0 2.0 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 OQR95013.1 - 7.7e-05 22.2 0.0 0.00032 20.1 0.0 2.0 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 OQR95013.1 - 0.0028 17.5 0.0 0.015 15.1 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 OQR95013.1 - 0.05 13.6 0.0 0.13 12.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Ribosomal_L19e PF01280.20 OQR95014.1 - 2.5e-64 215.7 11.0 2.5e-64 215.7 11.0 1.8 1 1 1 2 2 2 1 Ribosomal protein L19e YibE_F PF07907.11 OQR95015.1 - 7.1e-05 22.4 4.4 9.6e-05 22.0 4.4 1.3 1 0 0 1 1 1 1 YibE/F-like protein ATP-synt_I PF03899.15 OQR95015.1 - 0.0038 17.6 7.9 0.0038 17.6 7.9 1.7 1 1 0 1 1 1 1 ATP synthase I chain DUF3262 PF11660.8 OQR95015.1 - 0.036 14.5 1.2 0.036 14.5 1.2 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3262) MASE4 PF17158.4 OQR95015.1 - 0.12 11.7 6.2 0.14 11.4 5.6 1.4 1 1 0 1 1 1 0 Membrane-associated sensor, integral membrane domain Abhydrolase_9_N PF15420.6 OQR95015.1 - 0.18 11.8 3.1 0.28 11.2 2.8 1.4 1 1 0 1 1 1 0 Alpha/beta-hydrolase family N-terminus DUF1129 PF06570.11 OQR95015.1 - 0.19 11.2 4.9 0.24 10.9 4.8 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1129) DUF4570 PF15134.6 OQR95016.1 - 0.12 12.4 6.4 3.3 7.8 0.0 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4570) AAA_3 PF07726.11 OQR95017.1 - 0.087 12.7 0.0 0.1 12.5 0.0 1.1 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Ribosomal_L27A PF00828.19 OQR95018.1 - 8.8e-38 129.9 0.2 1.9e-37 128.8 0.2 1.6 1 0 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A PPV_E1_N PF00524.18 OQR95019.1 - 0.089 13.2 0.1 0.12 12.8 0.1 1.3 1 0 0 1 1 1 0 E1 Protein, N terminal domain Myb_DNA-binding PF00249.31 OQR95030.1 - 5.8e-30 103.2 6.8 3.4e-14 52.8 0.2 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OQR95030.1 - 4.2e-21 74.9 5.3 1.4e-16 60.5 1.1 2.5 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OQR95030.1 - 0.0004 20.2 0.1 0.0049 16.7 0.0 2.3 2 0 0 2 2 2 1 Myb DNA-binding like SANT_DAMP1_like PF16282.5 OQR95030.1 - 0.0022 18.1 1.0 0.0071 16.5 0.2 2.0 1 1 1 2 2 2 1 SANT/Myb-like domain of DAMP1 Myb_DNA-bind_4 PF13837.6 OQR95030.1 - 0.0024 18.2 3.2 0.0055 17.0 0.4 2.5 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain SLIDE PF09111.10 OQR95030.1 - 0.01 15.9 0.1 0.042 13.9 0.0 2.0 2 0 0 2 2 2 0 SLIDE Arm PF00514.23 OQR95031.1 - 0.056 13.5 0.0 9.9 6.4 0.0 3.1 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat WD40 PF00400.32 OQR95033.1 - 5.2e-27 93.6 10.0 2.1e-06 28.4 0.4 5.2 5 0 0 5 5 5 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OQR95033.1 - 7.2e-06 26.2 0.2 0.0099 16.2 0.2 2.9 1 1 2 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain DUF1921 PF09081.10 OQR95033.1 - 0.00031 20.9 1.2 1.8 8.9 0.0 4.1 4 2 0 4 4 4 2 Domain of unknown function (DUF1921) Ge1_WD40 PF16529.5 OQR95033.1 - 0.0019 17.2 0.0 2 7.3 0.0 2.9 1 1 2 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 OQR95033.1 - 0.01 14.5 0.3 2.5 6.6 0.1 2.9 2 1 1 3 3 3 0 Nucleoporin Nup120/160 OATP PF03137.20 OQR95034.1 - 4.2e-07 28.6 0.8 4.8e-07 28.4 0.8 1.1 1 0 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family adh_short PF00106.25 OQR95035.1 - 2.5e-27 95.6 1.5 1e-25 90.4 0.7 2.1 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 OQR95035.1 - 4.1e-24 85.4 0.9 8.2e-23 81.2 0.9 2.1 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OQR95035.1 - 5.7e-14 52.4 0.2 8.2e-14 51.9 0.2 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 OQR95035.1 - 4e-06 26.5 0.1 7e-06 25.7 0.1 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 OQR95035.1 - 2.7e-05 24.1 0.6 6.9e-05 22.8 0.6 1.7 1 1 0 1 1 1 1 NAD(P)H-binding ApbA PF02558.16 OQR95035.1 - 0.00088 18.9 0.1 0.0016 18.1 0.1 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA GDP_Man_Dehyd PF16363.5 OQR95035.1 - 0.0016 17.9 0.0 0.0022 17.5 0.0 1.5 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase DFP PF04127.15 OQR95035.1 - 0.012 15.5 0.2 0.02 14.7 0.2 1.3 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein YjeF_N PF03853.15 OQR95035.1 - 0.043 13.7 0.0 0.08 12.8 0.0 1.5 1 0 0 1 1 1 0 YjeF-related protein N-terminus F420_oxidored PF03807.17 OQR95035.1 - 0.055 14.0 0.3 0.16 12.6 0.1 1.8 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent TrkA_N PF02254.18 OQR95035.1 - 0.08 13.2 0.0 0.22 11.8 0.0 1.9 2 0 0 2 2 2 0 TrkA-N domain Pyr_redox_3 PF13738.6 OQR95035.1 - 0.14 11.4 0.0 0.2 10.8 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase OATP PF03137.20 OQR95036.1 - 0.00083 17.8 3.4 0.00084 17.7 0.1 2.4 3 1 0 3 3 3 1 Organic Anion Transporter Polypeptide (OATP) family MFS_1 PF07690.16 OQR95036.1 - 0.037 13.0 5.8 0.19 10.6 5.8 1.9 1 1 0 1 1 1 0 Major Facilitator Superfamily Peptidase_M32 PF02074.15 OQR95036.1 - 0.11 11.3 0.0 0.14 10.9 0.0 1.1 1 0 0 1 1 1 0 Carboxypeptidase Taq (M32) metallopeptidase DUF4938 PF16292.5 OQR95036.1 - 0.11 11.8 0.0 0.16 11.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4938) FKBP_C PF00254.28 OQR95041.1 - 4.1e-25 87.9 0.1 5e-25 87.6 0.1 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase NARG2_C PF10505.9 OQR95042.1 - 2.3e-18 66.5 0.1 4.6e-18 65.5 0.1 1.4 1 0 0 1 1 1 1 NMDA receptor-regulated gene protein 2 C-terminus Stomoxyn PF11585.8 OQR95042.1 - 0.64 10.1 3.6 0.56 10.3 1.1 2.2 2 0 0 2 2 2 0 Insect antimicrobial peptide, stomoxyn Syntaxin-18_N PF10496.9 OQR95043.1 - 5.7e-05 23.3 1.3 5.7e-05 23.3 1.3 3.0 2 2 0 2 2 2 1 SNARE-complex protein Syntaxin-18 N-terminus DASH_Dad3 PF08656.10 OQR95043.1 - 0.0084 16.2 3.4 0.048 13.7 0.2 3.0 3 0 0 3 3 3 1 DASH complex subunit Dad3 SNARE PF05739.19 OQR95043.1 - 0.011 15.7 0.0 0.011 15.7 0.0 2.1 3 0 0 3 3 3 0 SNARE domain MapZ_EC1 PF18041.1 OQR95043.1 - 0.025 14.8 2.0 0.049 13.9 0.2 2.1 2 0 0 2 2 2 0 MapZ extracellular domain 1 7TMR-HDED PF07697.11 OQR95043.1 - 0.06 13.5 2.2 0.095 12.8 2.2 1.3 1 0 0 1 1 1 0 7TM-HD extracellular RGS12_usC PF16612.5 OQR95043.1 - 0.15 12.5 3.5 0.4 11.1 3.4 1.8 1 1 0 1 1 1 0 C-terminal unstructured region of RGS12 Rsc14 PF08586.10 OQR95043.1 - 0.22 12.4 2.7 19 6.1 0.1 2.7 2 0 0 2 2 2 0 RSC complex, Rsc14/Ldb7 subunit Syntaxin-6_N PF09177.11 OQR95043.1 - 0.36 11.4 5.7 0.27 11.8 1.5 2.4 2 1 1 3 3 3 0 Syntaxin 6, N-terminal FTA4 PF13093.6 OQR95043.1 - 0.84 9.5 10.1 25 4.7 10.1 2.1 1 1 0 1 1 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 THOC7 PF05615.13 OQR95043.1 - 3.6 7.9 14.6 0.16 12.3 2.2 2.5 2 0 0 2 2 2 0 Tho complex subunit 7 FliJ PF02050.16 OQR95043.1 - 7.6 6.8 12.7 3.3 7.9 3.2 2.5 2 0 0 2 2 2 0 Flagellar FliJ protein Abhydrolase_1 PF00561.20 OQR95044.1 - 1.2e-07 31.6 0.1 2.2e-07 30.8 0.1 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 OQR95044.1 - 2.9e-05 24.8 0.0 0.00022 21.9 0.0 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 OQR95044.1 - 0.00029 20.2 0.0 0.0013 18.0 0.0 2.0 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Peptidase_S10 PF00450.22 OQR95044.1 - 0.094 12.1 0.0 3.4 7.0 0.0 2.1 2 0 0 2 2 2 0 Serine carboxypeptidase RRM_1 PF00076.22 OQR95045.1 - 3.2e-25 87.8 0.0 4.7e-12 45.5 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) NYN PF01936.18 OQR95045.1 - 9.2e-12 45.7 0.0 2.6e-10 40.9 0.0 2.7 2 1 0 2 2 2 1 NYN domain Nup35_RRM_2 PF14605.6 OQR95045.1 - 8.4e-06 25.7 0.0 0.013 15.5 0.0 2.4 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif RRM_7 PF16367.5 OQR95045.1 - 0.016 15.3 0.0 0.22 11.6 0.0 2.4 2 1 0 2 2 2 0 RNA recognition motif DUF1866 PF08952.11 OQR95045.1 - 0.12 12.2 0.0 16 5.3 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1866) CDC73_C PF05179.14 OQR95046.1 - 2.5e-46 157.3 0.3 6.2e-46 156.0 0.3 1.7 1 0 0 1 1 1 1 RNA pol II accessory factor, Cdc73 family, C-terminal Guanylate_cyc PF00211.20 OQR95046.1 - 7.9e-09 35.4 0.0 7.4e-08 32.2 0.0 2.2 1 1 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain CDC73_N PF16050.5 OQR95046.1 - 1.8e-08 34.1 4.1 1.3e-05 24.7 1.2 2.3 1 1 1 2 2 2 2 Paf1 complex subunit CDC73 N-terminal Clenterotox PF03505.14 OQR95046.1 - 0.025 14.2 0.1 0.059 13.0 0.1 1.6 1 0 0 1 1 1 0 Clostridium enterotoxin Myb_DNA-binding PF00249.31 OQR95047.1 - 1.7e-08 34.5 0.1 2.9e-08 33.8 0.1 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OQR95047.1 - 0.001 19.3 0.6 0.002 18.3 0.2 1.7 2 0 0 2 2 2 1 Myb-like DNA-binding domain RecC_C PF17946.1 OQR95047.1 - 0.054 13.3 0.1 0.066 13.0 0.1 1.1 1 0 0 1 1 1 0 RecC C-terminal domain DUF1168 PF06658.12 OQR95076.1 - 1e-28 99.8 12.3 1.5e-28 99.3 12.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1168) DUF4175 PF13779.6 OQR95076.1 - 0.0049 14.9 4.6 0.0055 14.7 4.6 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4175) MRP-L46 PF11788.8 OQR95076.1 - 0.008 16.9 3.8 0.016 16.0 3.8 1.4 1 0 0 1 1 1 1 39S mitochondrial ribosomal protein L46 PDEase_I_N PF08499.12 OQR95076.1 - 3.7 7.5 5.6 11 5.9 2.2 2.9 2 1 1 3 3 3 0 3'5'-cyclic nucleotide phosphodiesterase N-terminal Presenilin PF01080.17 OQR95076.1 - 7.7 5.2 5.0 8.1 5.1 5.0 1.1 1 0 0 1 1 1 0 Presenilin Response_reg PF00072.24 OQR95077.1 - 4e-16 59.2 0.1 1.4e-15 57.4 0.1 2.0 1 0 0 1 1 1 1 Response regulator receiver domain SAM_1 PF00536.30 OQR95077.1 - 1.3e-14 54.4 0.1 4.2e-14 52.7 0.1 2.0 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 OQR95077.1 - 6.6e-13 48.6 0.0 1.7e-12 47.2 0.0 1.8 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) IQ PF00612.27 OQR95077.1 - 6e-06 25.6 29.4 0.0011 18.6 0.6 6.6 6 0 0 6 6 6 2 IQ calmodulin-binding motif Ank_2 PF12796.7 OQR95077.1 - 4.7e-05 23.9 0.2 0.00028 21.4 0.0 2.4 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OQR95077.1 - 0.00014 22.0 0.0 0.055 14.0 0.0 3.0 2 0 0 2 2 2 1 Ankyrin repeat Ank_5 PF13857.6 OQR95077.1 - 0.00022 21.5 1.1 0.0084 16.4 0.1 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 OQR95077.1 - 0.00024 21.4 0.3 0.0008 19.7 0.3 2.0 1 0 0 1 1 1 1 Ankyrin repeat Ank_4 PF13637.6 OQR95077.1 - 0.00032 21.2 0.1 0.0022 18.5 0.1 2.5 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Hydrolase_4 PF12146.8 OQR95077.1 - 0.00099 18.4 0.0 0.0028 17.0 0.0 1.8 1 1 0 1 1 1 1 Serine aminopeptidase, S33 DUF3834 PF12916.7 OQR95077.1 - 0.0067 15.7 0.0 0.038 13.2 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF3834) GP52 PF17468.2 OQR95077.1 - 0.081 13.1 0.0 0.23 11.6 0.0 1.7 1 0 0 1 1 1 0 Phage gene product 52 T2SSF PF00482.23 OQR95077.1 - 0.1 12.6 0.1 0.51 10.3 0.0 2.2 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein F 14-3-3 PF00244.20 OQR95078.1 - 5.3e-103 343.3 4.6 6e-103 343.1 4.6 1.0 1 0 0 1 1 1 1 14-3-3 protein TPR_12 PF13424.6 OQR95078.1 - 0.031 14.6 0.1 1.3 9.4 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat Ribosomal_L7Ae PF01248.26 OQR95078.1 - 0.063 13.0 0.2 13 5.6 0.1 2.3 2 0 0 2 2 2 0 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family SecY PF00344.20 OQR95088.1 - 2.1e-73 247.2 16.7 2.7e-73 246.9 16.7 1.1 1 0 0 1 1 1 1 SecY translocase Plug_translocon PF10559.9 OQR95088.1 - 1.4e-17 63.2 1.3 2.5e-17 62.4 0.0 2.2 2 0 0 2 2 2 1 Plug domain of Sec61p Atypical_Card PF18461.1 OQR95089.1 - 1.1 9.5 3.7 54 4.1 0.0 3.4 2 2 1 3 3 3 0 Atypical caspase recruitment domain cNMP_binding PF00027.29 OQR95090.1 - 1.7e-40 137.0 0.3 7.6e-16 58.0 0.0 4.3 5 0 0 5 5 5 3 Cyclic nucleotide-binding domain RGS PF00615.19 OQR95090.1 - 7.5e-38 129.4 15.0 6.8e-22 78.0 2.1 4.2 3 0 0 3 3 3 2 Regulator of G protein signaling domain DnaJ PF00226.31 OQR95090.1 - 7.2e-09 35.6 0.0 2.5e-08 33.9 0.0 2.0 1 0 0 1 1 1 1 DnaJ domain Pkinase PF00069.25 OQR95090.1 - 4.7e-07 29.4 0.1 3.9e-05 23.2 0.0 3.8 3 1 0 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQR95090.1 - 7.8e-05 22.1 0.2 0.0013 18.0 0.0 2.5 2 0 0 2 2 2 1 Protein tyrosine kinase RGS-like PF09128.11 OQR95090.1 - 0.00076 19.2 2.8 0.078 12.7 0.3 3.3 2 0 0 2 2 2 2 Regulator of G protein signalling-like domain NUDIX PF00293.28 OQR95091.1 - 8.3e-14 51.8 0.1 5.7e-13 49.0 0.0 1.9 2 0 0 2 2 2 1 NUDIX domain SpoU_methylase PF00588.19 OQR95092.1 - 2e-18 66.9 0.0 2.8e-18 66.5 0.0 1.1 1 0 0 1 1 1 1 SpoU rRNA Methylase family Methyltrn_RNA_4 PF09936.9 OQR95092.1 - 0.1 12.5 0.0 1.8 8.4 0.0 2.1 2 0 0 2 2 2 0 SAM-dependent RNA methyltransferase Cyto_heme_lyase PF01265.17 OQR95093.1 - 0.17 11.4 5.8 0.21 11.2 5.8 1.1 1 0 0 1 1 1 0 Cytochrome c/c1 heme lyase TMA7 PF09072.10 OQR95093.1 - 1 10.2 12.8 0.71 10.8 7.2 2.4 2 1 0 2 2 2 0 Translation machinery associated TMA7 FAM76 PF16046.5 OQR95093.1 - 5.6 6.2 15.6 7 5.9 15.6 1.1 1 0 0 1 1 1 0 FAM76 protein PPL5 PF18168.1 OQR95093.1 - 6 6.1 9.7 6.2 6.0 9.7 1.1 1 0 0 1 1 1 0 Prim-pol family 5 Adaptin_binding PF10199.9 OQR95093.1 - 9.3 6.9 16.2 15 6.2 16.2 1.4 1 0 0 1 1 1 0 Alpha and gamma adaptin binding protein p34 dCMP_cyt_deam_1 PF00383.23 OQR95121.1 - 1.5e-16 60.1 0.4 1.8e-16 59.8 0.4 1.1 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region dCMP_cyt_deam_2 PF08211.12 OQR95121.1 - 6.5e-13 49.0 2.6 4.8e-11 43.0 0.3 2.1 2 0 0 2 2 2 2 Cytidine and deoxycytidylate deaminase zinc-binding region LmjF365940-deam PF14421.6 OQR95121.1 - 0.055 13.1 1.8 4.9 6.7 0.3 2.1 1 1 1 2 2 2 0 A distinct subfamily of CDD/CDA-like deaminases EAF PF09816.9 OQR95124.1 - 2.8e-15 56.5 0.0 3.3e-15 56.3 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase II transcription elongation factor Anoctamin PF04547.12 OQR95125.1 - 1.8e-63 214.9 20.7 1.8e-63 214.9 20.7 2.3 2 0 0 2 2 2 1 Calcium-activated chloride channel Ion_trans_2 PF07885.16 OQR95125.1 - 8.9e-11 41.6 5.4 8.9e-11 41.6 5.4 2.9 2 0 0 2 2 2 1 Ion channel Patatin PF01734.22 OQR95125.1 - 4.4e-06 27.0 2.9 0.073 13.2 0.1 2.8 1 1 0 2 2 2 2 Patatin-like phospholipase EF-hand_7 PF13499.6 OQR95125.1 - 0.019 15.4 0.4 0.067 13.6 0.0 2.2 2 0 0 2 2 2 0 EF-hand domain pair EF-hand_6 PF13405.6 OQR95125.1 - 0.031 14.2 2.2 6.8 6.9 0.1 3.4 3 0 0 3 3 3 0 EF-hand domain EF-hand_1 PF00036.32 OQR95125.1 - 0.16 11.6 1.0 47 3.9 0.1 3.5 3 0 0 3 3 3 0 EF hand GIDA PF01134.22 OQR95126.1 - 1.3e-154 515.0 0.0 1.7e-154 514.6 0.0 1.1 1 0 0 1 1 1 1 Glucose inhibited division protein A GIDA_assoc PF13932.6 OQR95126.1 - 1.2e-63 215.1 0.0 1.7e-63 214.6 0.0 1.2 1 0 0 1 1 1 1 GidA associated domain Pyr_redox_2 PF07992.14 OQR95126.1 - 4.6e-08 32.6 0.5 2.2e-07 30.4 0.5 2.0 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 OQR95126.1 - 8.8e-08 31.9 2.0 1.6e-07 31.1 2.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 OQR95126.1 - 3.7e-06 26.3 3.7 8.5e-06 25.1 2.5 2.0 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.14 OQR95126.1 - 0.00021 20.1 2.9 0.0057 15.4 0.4 2.5 3 0 0 3 3 3 1 HI0933-like protein DAO PF01266.24 OQR95126.1 - 0.00029 20.5 0.7 0.14 11.7 0.9 2.5 2 0 0 2 2 2 2 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 OQR95126.1 - 0.0008 18.8 1.3 0.0019 17.5 1.3 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox PF00070.27 OQR95126.1 - 0.001 19.6 0.2 0.0025 18.3 0.2 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 OQR95126.1 - 0.0066 15.7 1.1 0.065 12.5 0.1 2.4 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 OQR95126.1 - 0.0071 15.4 1.2 0.02 13.9 1.2 1.7 1 1 0 1 1 1 1 Lycopene cyclase protein Thi4 PF01946.17 OQR95126.1 - 0.047 12.9 0.5 0.093 12.0 0.5 1.4 1 0 0 1 1 1 0 Thi4 family Trp_halogenase PF04820.14 OQR95126.1 - 0.13 11.0 0.7 1.5 7.6 0.9 2.0 2 0 0 2 2 2 0 Tryptophan halogenase NAD_binding_8 PF13450.6 OQR95126.1 - 0.16 12.2 1.2 0.36 11.1 1.2 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain AAA PF00004.29 OQR95127.1 - 8.2e-20 71.6 0.0 8.4e-19 68.3 0.0 2.5 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 OQR95127.1 - 1.4e-05 25.2 0.0 8.4e-05 22.6 0.0 2.5 2 1 0 2 2 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 OQR95127.1 - 3e-05 24.5 0.0 5.1e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_28 PF13521.6 OQR95127.1 - 0.0013 19.0 0.0 0.0026 18.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 OQR95127.1 - 0.0016 18.3 0.5 0.0044 16.8 0.0 1.9 2 0 0 2 2 2 1 AAA domain DUF815 PF05673.13 OQR95127.1 - 0.0017 17.6 0.0 0.0031 16.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_22 PF13401.6 OQR95127.1 - 0.002 18.4 0.1 0.0073 16.6 0.0 1.9 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 OQR95127.1 - 0.0037 17.6 2.0 0.025 15.0 0.0 3.0 4 0 0 4 4 2 1 RNA helicase AAA_33 PF13671.6 OQR95127.1 - 0.0043 17.2 0.0 0.02 15.1 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 OQR95127.1 - 0.0053 17.3 0.0 0.017 15.7 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_7 PF12775.7 OQR95127.1 - 0.0076 15.8 0.0 0.02 14.4 0.0 1.7 1 0 0 1 1 1 1 P-loop containing dynein motor region RuvB_N PF05496.12 OQR95127.1 - 0.012 15.4 0.0 0.022 14.5 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_14 PF13173.6 OQR95127.1 - 0.013 15.6 0.3 0.081 13.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 OQR95127.1 - 0.016 14.9 0.0 0.045 13.5 0.0 1.7 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_30 PF13604.6 OQR95127.1 - 0.017 14.9 0.0 0.03 14.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain PPV_E1_C PF00519.17 OQR95127.1 - 0.019 13.8 1.3 0.037 12.9 0.1 1.8 2 0 0 2 2 2 0 Papillomavirus helicase Bac_DnaA PF00308.18 OQR95127.1 - 0.023 14.5 0.0 0.058 13.2 0.0 1.6 1 0 0 1 1 1 0 Bacterial dnaA protein ABC_tran PF00005.27 OQR95127.1 - 0.028 14.9 0.1 0.077 13.5 0.0 1.8 2 0 0 2 2 1 0 ABC transporter Zeta_toxin PF06414.12 OQR95127.1 - 0.03 13.6 0.0 0.058 12.7 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_6 PF12774.7 OQR95127.1 - 0.064 12.2 0.0 0.11 11.4 0.0 1.3 1 0 0 1 1 1 0 Hydrolytic ATP binding site of dynein motor region AAA_19 PF13245.6 OQR95127.1 - 0.068 13.5 0.1 0.17 12.3 0.1 1.6 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 OQR95127.1 - 0.069 13.1 0.0 0.15 12.1 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_3 PF07726.11 OQR95127.1 - 0.096 12.5 0.0 0.23 11.3 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Viral_helicase1 PF01443.18 OQR95127.1 - 0.11 12.2 0.0 0.3 10.8 0.0 1.7 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Mg_chelatase PF01078.21 OQR95127.1 - 0.13 11.6 0.0 0.23 10.8 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI NACHT PF05729.12 OQR95127.1 - 0.19 11.6 0.0 0.42 10.5 0.0 1.5 1 0 0 1 1 1 0 NACHT domain AAA_29 PF13555.6 OQR95127.1 - 0.23 11.2 0.7 0.58 9.9 0.0 2.0 2 0 0 2 2 2 0 P-loop containing region of AAA domain Kinesin PF00225.23 OQR95128.1 - 2.7e-98 329.0 0.6 4.1e-98 328.4 0.6 1.3 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 OQR95128.1 - 2.2e-22 79.6 1.5 3.4e-22 79.0 0.1 2.0 2 1 0 2 2 2 1 Microtubule binding AAA_22 PF13401.6 OQR95128.1 - 0.034 14.4 1.0 0.079 13.2 0.0 2.1 2 0 0 2 2 2 0 AAA domain ATG16 PF08614.11 OQR95128.1 - 0.05 13.8 19.9 0.44 10.7 19.9 2.5 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) AAA_16 PF13191.6 OQR95128.1 - 0.2 12.0 1.6 0.67 10.3 0.0 2.5 3 0 0 3 3 3 0 AAA ATPase domain AAA_7 PF12775.7 OQR95128.1 - 0.22 11.0 2.0 0.26 10.8 0.0 2.2 3 0 0 3 3 3 0 P-loop containing dynein motor region YgaB PF14182.6 OQR95128.1 - 0.86 10.0 10.8 3.1 8.3 10.8 1.9 1 0 0 1 1 1 0 YgaB-like protein Herpes_BLRF2 PF05812.12 OQR95128.1 - 6.9 6.8 18.0 5.1 7.3 3.5 4.1 3 1 1 4 4 4 0 Herpesvirus BLRF2 protein NAD_binding_2 PF03446.15 OQR95129.1 - 2.1e-48 164.5 1.1 3.1e-48 163.9 1.1 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 OQR95129.1 - 5.3e-35 120.3 1.3 9.9e-35 119.4 1.3 1.5 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.17 OQR95129.1 - 1.8e-08 34.8 0.0 4.4e-08 33.6 0.0 1.7 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.19 OQR95129.1 - 0.00014 21.3 0.0 0.00022 20.6 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.18 OQR95129.1 - 0.00049 20.0 0.0 0.001 19.0 0.0 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 OQR95129.1 - 0.00087 19.4 0.1 0.0029 17.7 0.0 2.0 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase ApbA PF02558.16 OQR95129.1 - 0.039 13.6 0.2 0.14 11.8 0.0 1.9 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA Sacchrp_dh_NADP PF03435.18 OQR95129.1 - 0.048 13.9 0.0 1.6 9.0 0.0 2.2 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain DUF87 PF01935.17 OQR95130.1 - 0.00018 21.7 1.4 0.00019 21.6 1.4 1.1 1 0 0 1 1 1 1 Helicase HerA, central domain Helo_like_N PF17111.5 OQR95130.1 - 0.028 13.8 4.0 0.052 12.9 4.0 1.4 1 0 0 1 1 1 0 Fungal N-terminal domain of STAND proteins Exonuc_VII_L PF02601.15 OQR95130.1 - 0.051 13.1 0.8 0.048 13.2 0.8 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF1943 PF09172.11 OQR95130.1 - 0.056 12.7 1.9 0.075 12.3 1.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1943) Acyl-CoA_ox_N PF14749.6 OQR95130.1 - 0.13 12.8 2.5 0.19 12.3 2.5 1.2 1 0 0 1 1 1 0 Acyl-coenzyme A oxidase N-terminal TMPIT PF07851.13 OQR95130.1 - 1.6 7.9 7.3 2.1 7.5 7.3 1.2 1 0 0 1 1 1 0 TMPIT-like protein XhlA PF10779.9 OQR95130.1 - 2.8 8.2 8.2 2.6 8.3 2.6 2.3 1 1 1 2 2 2 0 Haemolysin XhlA SseC PF04888.12 OQR95130.1 - 9.9 5.7 6.7 4.5 6.8 4.4 1.6 1 1 1 2 2 2 0 Secretion system effector C (SseC) like family DIOX_N PF14226.6 OQR95131.1 - 1.4e-10 42.0 0.0 2.9e-10 40.9 0.0 1.6 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 OQR95131.1 - 0.0026 18.2 0.0 0.0051 17.3 0.0 1.6 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily ASCH PF04266.14 OQR95131.1 - 0.089 13.4 0.1 0.3 11.7 0.0 2.0 2 0 0 2 2 2 0 ASCH domain Ank_2 PF12796.7 OQR95132.1 - 1.5e-38 131.2 3.8 4.6e-10 40.0 0.0 4.8 2 1 4 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQR95132.1 - 4.1e-29 100.6 3.3 7.1e-11 42.4 0.0 6.0 4 3 2 6 6 6 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 OQR95132.1 - 3.7e-26 90.8 2.2 2.5e-10 40.4 0.1 5.0 3 2 2 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQR95132.1 - 1.1e-25 86.9 2.2 6.1e-05 23.1 0.0 7.5 7 0 0 7 7 7 4 Ankyrin repeat Ank PF00023.30 OQR95132.1 - 1e-22 79.5 4.3 0.00033 21.0 0.0 6.2 6 0 0 6 6 6 4 Ankyrin repeat Fic PF02661.18 OQR95132.1 - 5.1e-14 52.9 0.0 2e-13 51.0 0.0 2.1 1 0 0 1 1 1 1 Fic/DOC family TruB_C_2 PF16198.5 OQR95132.1 - 0.11 12.7 0.0 0.35 11.0 0.0 1.8 1 0 0 1 1 1 0 tRNA pseudouridylate synthase B C-terminal domain NAD_binding_2 PF03446.15 OQR95133.1 - 1.7e-49 168.0 1.9 3e-49 167.2 1.9 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 OQR95133.1 - 3.1e-34 117.8 3.5 3.7e-34 117.6 2.2 1.7 2 0 0 2 2 2 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.17 OQR95133.1 - 2.2e-07 31.4 0.0 5.9e-07 30.0 0.0 1.8 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.19 OQR95133.1 - 0.0002 20.8 0.0 0.00032 20.1 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_10 PF13460.6 OQR95133.1 - 0.00021 21.3 0.0 0.00076 19.4 0.0 1.8 1 1 0 1 1 1 1 NAD(P)H-binding Shikimate_DH PF01488.20 OQR95133.1 - 0.00051 20.1 0.2 0.0012 18.9 0.0 1.9 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.6 OQR95133.1 - 0.00059 20.2 0.1 0.003 18.0 0.0 2.1 2 0 0 2 2 2 1 Putative NAD(P)-binding Sacchrp_dh_NADP PF03435.18 OQR95133.1 - 0.0014 18.9 0.0 0.0096 16.2 0.0 2.0 1 1 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain 3HCDH_N PF02737.18 OQR95133.1 - 0.0031 17.4 0.0 0.0076 16.2 0.0 1.7 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ApbA PF02558.16 OQR95133.1 - 0.019 14.6 0.1 0.019 14.6 0.1 1.8 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA EF-hand_1 PF00036.32 OQR95159.1 - 4.5e-10 38.4 1.9 0.00011 21.5 0.0 2.3 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 OQR95159.1 - 5.1e-10 39.6 1.3 6.2e-10 39.4 1.3 1.1 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 OQR95159.1 - 1.3e-06 27.9 2.2 0.027 14.4 0.4 2.3 2 0 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.6 OQR95159.1 - 0.00011 22.0 0.2 0.00011 22.0 0.2 2.5 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_5 PF13202.6 OQR95159.1 - 0.0006 19.2 1.1 0.16 11.5 0.5 2.5 2 0 0 2 2 2 2 EF hand EF-hand_4 PF12763.7 OQR95159.1 - 0.03 14.3 1.3 0.05 13.6 0.7 1.7 1 1 1 2 2 2 0 Cytoskeletal-regulatory complex EF hand YusW PF14039.6 OQR95159.1 - 0.03 14.8 0.2 0.033 14.7 0.2 1.1 1 0 0 1 1 1 0 YusW-like protein Ank_2 PF12796.7 OQR95160.1 - 2.7e-21 75.9 2.2 3.2e-13 50.1 1.3 2.2 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OQR95160.1 - 9.7e-19 67.2 5.6 6e-09 36.0 0.1 2.8 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 OQR95160.1 - 1.3e-16 60.8 3.4 4.5e-09 36.7 0.8 3.5 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 OQR95160.1 - 2.3e-12 46.7 8.3 0.00011 22.5 0.1 4.0 5 0 0 5 5 5 3 Ankyrin repeat Ank_3 PF13606.6 OQR95160.1 - 9.9e-11 40.9 3.7 0.0048 17.3 0.1 4.2 5 0 0 5 5 5 3 Ankyrin repeat Copper-bind PF00127.20 OQR95160.1 - 0.00024 21.5 0.4 0.001 19.4 0.4 2.0 1 1 0 1 1 1 1 Copper binding proteins, plastocyanin/azurin family Cupredoxin_1 PF13473.6 OQR95160.1 - 0.0032 17.6 0.0 0.0061 16.6 0.0 1.5 1 0 0 1 1 1 1 Cupredoxin-like domain DNase_II PF03265.15 OQR95161.1 - 4.7e-20 72.1 4.8 2.5e-19 69.7 4.8 2.1 1 1 0 1 1 1 1 Deoxyribonuclease II Lipocalin_4 PF13648.6 OQR95161.1 - 0.033 15.2 2.1 0.043 14.8 0.8 1.9 2 0 0 2 2 2 0 Lipocalin-like domain RRM_1 PF00076.22 OQR95163.1 - 5e-48 160.8 0.0 1.4e-16 60.0 0.0 3.1 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 OQR95163.1 - 5.3e-05 23.0 0.0 0.13 12.2 0.0 2.6 3 0 0 3 3 3 2 Occluded RNA-recognition motif RRM_3 PF08777.11 OQR95163.1 - 0.00028 20.9 0.0 0.81 9.8 0.0 3.2 3 0 0 3 3 3 1 RNA binding motif Limkain-b1 PF11608.8 OQR95163.1 - 0.00037 20.5 0.0 0.014 15.5 0.0 2.6 2 0 0 2 2 2 1 Limkain b1 RRM_7 PF16367.5 OQR95163.1 - 0.1 12.8 0.0 7 6.8 0.0 2.8 3 0 0 3 3 3 0 RNA recognition motif Cyt-b5 PF00173.28 OQR95164.1 - 5.7e-09 36.0 0.0 0.0051 16.9 0.0 2.4 2 1 0 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain Ribonuc_red_lgC PF02867.15 OQR95193.1 - 6.8e-12 44.7 0.3 1.7e-05 23.6 0.1 3.1 3 0 0 3 3 3 3 Ribonucleotide reductase, barrel domain Agenet PF05641.12 OQR95194.1 - 8.2e-07 29.4 0.0 3e-06 27.6 0.0 2.0 1 0 0 1 1 1 1 Agenet domain TUDOR_5 PF18359.1 OQR95194.1 - 4.7e-05 23.0 0.0 8.3e-05 22.2 0.0 1.4 1 0 0 1 1 1 1 Histone methyltransferase Tudor domain 1 SpoIIIAH PF12685.7 OQR95194.1 - 0.0011 18.9 0.9 0.0011 18.9 0.9 2.1 2 0 0 2 2 2 1 SpoIIIAH-like protein Tudor_2 PF18104.1 OQR95194.1 - 0.0021 17.7 0.2 0.004 16.8 0.2 1.5 1 0 0 1 1 1 1 Jumonji domain-containing protein 2A Tudor domain TUDOR PF00567.24 OQR95194.1 - 0.0045 17.0 0.0 0.0095 16.0 0.0 1.5 1 0 0 1 1 1 1 Tudor domain MRI PF15325.6 OQR95194.1 - 0.0061 17.6 1.5 0.0061 17.6 1.5 2.6 2 1 0 2 2 2 1 Modulator of retrovirus infection SMG1_N PF17229.2 OQR95194.1 - 0.0063 17.2 1.4 0.0063 17.2 1.4 1.8 2 0 0 2 2 1 1 Serine/threonine-protein kinase SMG1 N-terminal Tudor_3 PF18115.1 OQR95194.1 - 0.0077 16.1 0.0 0.014 15.2 0.0 1.4 1 0 0 1 1 1 1 DNA repair protein Crb2 Tudor domain DUF4537 PF15057.6 OQR95194.1 - 0.015 15.3 0.0 0.028 14.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4537) HAS-barrel PF09378.10 OQR95194.1 - 0.21 11.8 0.7 1 9.6 0.8 2.0 1 1 0 1 1 1 0 HAS barrel domain SID-1_RNA_chan PF13965.6 OQR95194.1 - 0.28 9.6 0.2 0.43 8.9 0.2 1.3 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 DUF4834 PF16118.5 OQR95194.1 - 0.33 11.9 0.1 0.33 11.9 0.1 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4834) Connexin PF00029.19 OQR95194.1 - 2.1 8.1 3.9 1.3 8.8 0.1 2.1 2 0 0 2 2 2 0 Connexin SOBP PF15279.6 OQR95194.1 - 3.2 8.3 12.4 1.7 9.2 2.3 2.1 2 0 0 2 2 2 0 Sine oculis-binding protein CCDC53 PF10152.9 OQR95194.1 - 5 7.5 13.9 5.3 7.5 4.7 2.2 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex Striatin PF08232.12 OQR95194.1 - 6.5 7.3 15.2 3.7 8.1 3.4 2.2 2 0 0 2 2 2 0 Striatin family FAM176 PF14851.6 OQR95194.1 - 9.1 5.9 9.5 0.35 10.5 0.1 2.5 2 1 1 3 3 3 0 FAM176 family RCC1 PF00415.18 OQR95198.1 - 1.2e-70 233.9 19.7 6.3e-13 49.1 0.2 8.3 7 1 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 OQR95198.1 - 1.2e-34 117.4 39.0 1.3e-08 34.4 2.6 6.9 6 0 0 6 6 6 6 Regulator of chromosome condensation (RCC1) repeat SPRY PF00622.28 OQR95198.1 - 1.7e-32 112.1 0.2 2.5e-16 59.9 0.0 2.8 2 0 0 2 2 2 2 SPRY domain Laminin_G_3 PF13385.6 OQR95198.1 - 6.7e-10 39.3 0.0 2e-09 37.8 0.0 1.8 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily DUF4705 PF15788.5 OQR95198.1 - 0.33 11.2 1.9 0.77 10.0 1.9 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4705) EamA PF00892.20 OQR95199.1 - 0.0019 18.4 9.1 0.0035 17.5 9.1 1.5 1 1 0 1 1 1 1 EamA-like transporter family K1 PF02960.14 OQR95199.1 - 0.054 13.6 0.2 0.08 13.1 0.2 1.4 1 0 0 1 1 1 0 K1 glycoprotein PGBA_N PF15436.6 OQR95200.1 - 0.014 15.1 0.0 0.024 14.3 0.0 1.4 1 0 0 1 1 1 0 Plasminogen-binding protein pgbA N-terminal CHAP PF05257.16 OQR95202.1 - 1.4e-11 44.8 0.0 2.4e-11 44.0 0.0 1.4 1 0 0 1 1 1 1 CHAP domain Ank_2 PF12796.7 OQR95260.1 - 1.6e-35 121.5 5.6 1.1e-15 57.9 0.1 2.6 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQR95260.1 - 1.4e-24 86.2 0.7 1e-13 51.5 0.0 3.7 2 2 2 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 OQR95260.1 - 3.2e-21 74.8 2.8 6.3e-06 26.4 0.0 4.7 5 0 0 5 5 5 3 Ankyrin repeat Ank_3 PF13606.6 OQR95260.1 - 2.9e-20 70.2 0.4 9.2e-05 22.6 0.0 4.7 5 0 0 5 5 5 3 Ankyrin repeat Ank_5 PF13857.6 OQR95260.1 - 6.5e-16 58.2 0.5 1.3e-06 28.6 0.0 3.5 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Shigella_OspC PF06128.11 OQR95260.1 - 0.022 14.5 0.1 7.9 6.1 0.0 2.8 1 1 2 3 3 3 0 Shigella flexneri OspC protein VWA_3_C PF18571.1 OQR95260.1 - 0.027 14.4 0.9 3.9 7.4 0.0 3.3 3 0 0 3 3 3 0 von Willebrand factor type A C-terminal domain adh_short PF00106.25 OQR95261.1 - 1.8e-05 24.3 0.0 3e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OQR95261.1 - 0.00079 19.0 0.0 0.0011 18.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 OQR95261.1 - 0.12 11.8 0.0 0.14 11.6 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family PX PF00787.24 OQR95262.1 - 1.8e-05 24.7 0.1 4.6e-05 23.4 0.0 1.7 1 1 1 2 2 2 1 PX domain adh_short PF00106.25 OQR95263.1 - 7.7e-18 64.7 0.2 1e-15 57.8 0.1 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 OQR95263.1 - 9.4e-09 35.2 0.0 1.4e-06 28.1 0.0 2.2 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OQR95263.1 - 2.9e-05 24.0 0.0 4.7e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 KR domain RCC1 PF00415.18 OQR95264.1 - 1.6e-51 172.7 12.8 6.3e-15 55.5 0.3 5.4 5 0 0 5 5 5 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 OQR95264.1 - 1.7e-22 78.6 27.2 7.7e-09 35.1 0.8 5.9 5 1 0 5 5 5 4 Regulator of chromosome condensation (RCC1) repeat Desulfoferrodox PF01880.18 OQR95264.1 - 0.18 12.4 0.1 0.39 11.3 0.1 1.4 1 0 0 1 1 1 0 Desulfoferrodoxin PRT_C PF08372.10 OQR95285.1 - 6.6e-07 29.2 0.1 4.8e-06 26.4 0.0 2.1 2 0 0 2 2 2 1 Plant phosphoribosyltransferase C-terminal Reticulon PF02453.17 OQR95285.1 - 0.00044 20.3 4.0 0.39 10.7 0.3 2.4 2 0 0 2 2 2 2 Reticulon DUF639 PF04842.12 OQR95285.1 - 0.0029 17.1 0.6 0.017 14.6 0.1 2.1 2 0 0 2 2 2 1 Plant protein of unknown function (DUF639) Pex24p PF06398.11 OQR95285.1 - 0.041 12.9 2.9 0.18 10.8 0.1 2.1 2 0 0 2 2 2 0 Integral peroxisomal membrane peroxin 14-3-3 PF00244.20 OQR95285.1 - 0.12 11.9 0.0 0.21 11.1 0.0 1.3 1 0 0 1 1 1 0 14-3-3 protein FCD PF07729.12 OQR95286.1 - 0.063 13.7 0.1 0.16 12.4 0.1 1.7 1 0 0 1 1 1 0 FCD domain YL1 PF05764.13 OQR95286.1 - 0.82 9.7 12.5 0.12 12.4 2.8 2.4 2 0 0 2 2 2 0 YL1 nuclear protein TraC PF07820.12 OQR95286.1 - 4.4 7.7 7.5 4.1 7.8 0.3 2.5 2 0 0 2 2 2 0 TraC-like protein Ank PF00023.30 OQR95287.1 - 0.0012 19.2 0.0 0.0042 17.5 0.0 2.0 1 0 0 1 1 1 1 Ankyrin repeat Ank_5 PF13857.6 OQR95287.1 - 0.03 14.7 0.0 0.077 13.3 0.0 1.7 1 0 0 1 1 1 0 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQR95287.1 - 0.036 14.6 0.1 0.53 11.0 0.0 2.6 2 0 0 2 2 2 0 Ankyrin repeat Ank_4 PF13637.6 OQR95287.1 - 0.044 14.4 0.1 0.35 11.5 0.1 2.4 1 1 1 2 2 2 0 Ankyrin repeats (many copies) UPF0029 PF01205.19 OQR95288.1 - 2.5e-34 117.8 0.2 3.5e-34 117.3 0.2 1.2 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 RWD PF05773.22 OQR95288.1 - 6.9e-09 36.0 0.1 1.2e-08 35.3 0.1 1.3 1 0 0 1 1 1 1 RWD domain Gene66 PF02053.15 OQR95288.1 - 0.17 11.5 0.3 0.78 9.3 0.0 1.9 2 0 0 2 2 2 0 Gene 66 (IR5) protein 3HCDH_N PF02737.18 OQR95289.1 - 2.6e-57 193.6 0.0 3.5e-57 193.2 0.0 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.22 OQR95289.1 - 8.4e-30 103.2 0.2 8.8e-29 100.0 0.0 2.4 3 0 0 3 3 3 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain NAD_binding_2 PF03446.15 OQR95289.1 - 3e-05 24.3 2.3 5.2e-05 23.5 2.3 1.5 1 1 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 2-Hacid_dh_C PF02826.19 OQR95289.1 - 0.0081 15.5 0.6 0.014 14.7 0.5 1.4 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.14 OQR95289.1 - 0.037 13.6 0.2 0.051 13.1 0.2 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain F420_oxidored PF03807.17 OQR95289.1 - 0.039 14.5 0.4 0.097 13.3 0.4 1.8 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent DUF1681 PF07933.14 OQR95290.1 - 1.7e-52 177.0 0.0 2.1e-52 176.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1681) sCache_like PF16736.5 OQR95290.1 - 0.13 12.4 0.0 0.33 11.1 0.1 1.6 2 0 0 2 2 2 0 Single Cache-like Aa_trans PF01490.18 OQR95295.1 - 7.6e-52 176.4 27.4 1e-51 176.0 27.4 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Ras PF00071.22 OQR95295.1 - 1.2e-19 70.5 0.0 2.7e-19 69.4 0.0 1.6 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OQR95295.1 - 2.5e-13 50.3 0.0 5.6e-13 49.2 0.0 1.6 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SH2 PF00017.24 OQR95295.1 - 7.1e-08 32.4 0.1 1.5e-07 31.4 0.1 1.5 1 0 0 1 1 1 1 SH2 domain MMR_HSR1 PF01926.23 OQR95295.1 - 0.0045 17.1 0.0 0.0088 16.1 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase RabGAP-TBC PF00566.18 OQR95296.1 - 1.1e-25 90.5 1.7 1.3e-24 87.1 1.7 2.3 1 1 0 1 1 1 1 Rab-GTPase-TBC domain F-box PF00646.33 OQR95296.1 - 4e-08 33.0 1.5 1.4e-07 31.2 1.5 1.9 1 0 0 1 1 1 1 F-box domain DUF2841 PF11001.8 OQR95296.1 - 0.029 14.4 0.5 6.7 6.8 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2841) F-box-like PF12937.7 OQR95296.1 - 0.042 13.7 0.6 0.11 12.5 0.6 1.7 1 0 0 1 1 1 0 F-box-like EMP70 PF02990.16 OQR95297.1 - 2.8e-157 524.5 18.7 4.2e-157 523.9 18.7 1.3 1 0 0 1 1 1 1 Endomembrane protein 70 Glucosamine_iso PF01182.20 OQR95299.1 - 3.3e-71 239.8 0.0 3.8e-71 239.5 0.0 1.0 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase Sacchrp_dh_C PF16653.5 OQR95300.1 - 1.4e-85 287.7 0.0 2.1e-85 287.0 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase C-terminal domain AlaDh_PNT_N PF05222.15 OQR95300.1 - 8.7e-28 97.3 0.0 2e-27 96.2 0.0 1.7 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain Sacchrp_dh_NADP PF03435.18 OQR95300.1 - 6.4e-17 62.0 0.1 1.6e-16 60.8 0.1 1.7 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Saccharop_dh_N PF04455.12 OQR95300.1 - 8.4e-13 48.6 0.0 3.1e-12 46.8 0.0 2.0 1 0 0 1 1 1 1 LOR/SDH bifunctional enzyme conserved region AlaDh_PNT_C PF01262.21 OQR95300.1 - 0.0005 19.4 0.0 0.012 14.9 0.0 2.8 2 1 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain ApbA PF02558.16 OQR95300.1 - 0.1 12.2 0.3 1.9 8.1 0.0 2.5 3 0 0 3 3 3 0 Ketopantoate reductase PanE/ApbA K_channel_TID PF07941.11 OQR95300.1 - 0.11 12.9 2.0 0.3 11.6 2.0 1.6 1 0 0 1 1 1 0 Potassium channel Kv1.4 tandem inactivation domain MatE PF01554.18 OQR95320.1 - 5.6e-13 48.9 15.4 5.2e-11 42.4 11.1 3.4 2 2 0 2 2 2 2 MatE DUF2645 PF10840.8 OQR95320.1 - 0.49 11.1 8.5 3.8 8.2 2.5 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2645) PP2C PF00481.21 OQR95323.1 - 3.6e-37 128.4 0.0 9.7e-37 127.0 0.0 1.6 2 0 0 2 2 2 1 Protein phosphatase 2C Pkinase PF00069.25 OQR95323.1 - 8.4e-27 94.2 0.0 1.6e-26 93.3 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain cNMP_binding PF00027.29 OQR95323.1 - 6.6e-22 77.4 0.0 7.4e-12 45.2 0.0 3.5 2 1 0 2 2 2 2 Cyclic nucleotide-binding domain Pkinase_Tyr PF07714.17 OQR95323.1 - 5e-11 42.4 0.0 8.6e-11 41.6 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase PP2C_2 PF13672.6 OQR95323.1 - 2.4e-05 24.1 0.0 0.00015 21.4 0.0 2.1 2 0 0 2 2 2 1 Protein phosphatase 2C Kinase-like PF14531.6 OQR95323.1 - 0.00025 20.5 0.0 0.00045 19.6 0.0 1.4 1 0 0 1 1 1 1 Kinase-like RdRP PF05183.12 OQR95324.1 - 1.2e-127 427.0 0.0 3.8e-85 286.7 0.0 2.1 2 0 0 2 2 2 2 RNA dependent RNA polymerase Pkinase_Tyr PF07714.17 OQR95330.1 - 7.9e-56 189.2 0.0 1e-55 188.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OQR95330.1 - 5.4e-53 180.0 0.0 7.5e-53 179.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 OQR95330.1 - 0.00049 19.5 0.0 0.00079 18.8 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 OQR95330.1 - 0.0014 17.7 0.0 0.002 17.1 0.0 1.1 1 0 0 1 1 1 1 Haspin like kinase domain EGF PF00008.27 OQR95330.1 - 0.0029 17.9 11.8 0.0029 17.9 11.8 12.4 12 0 0 12 12 12 3 EGF-like domain APH PF01636.23 OQR95330.1 - 0.0097 15.9 0.2 0.0097 15.9 0.2 1.6 2 0 0 2 2 2 1 Phosphotransferase enzyme family hEGF PF12661.7 OQR95330.1 - 0.017 15.8 10.5 0.017 15.8 10.5 13.1 13 0 0 13 13 13 0 Human growth factor-like EGF Kdo PF06293.14 OQR95330.1 - 0.051 12.9 0.0 0.088 12.2 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 OQR95330.1 - 0.13 11.0 0.0 0.19 10.4 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase PX PF00787.24 OQR95331.1 - 1.7e-07 31.2 0.3 2.7e-07 30.6 0.3 1.3 1 0 0 1 1 1 1 PX domain TAFII28 PF04719.14 OQR95332.1 - 1.8e-26 92.0 0.2 2.8e-26 91.4 0.2 1.3 1 0 0 1 1 1 1 hTAFII28-like protein conserved region CDC45 PF02724.14 OQR95332.1 - 0.026 12.8 7.8 0.023 13.0 7.8 1.1 1 0 0 1 1 1 0 CDC45-like protein TetR_C_25 PF17933.1 OQR95332.1 - 0.041 14.2 0.0 0.078 13.3 0.0 1.4 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain MDM1 PF15501.6 OQR95332.1 - 0.22 10.6 6.0 0.25 10.4 6.0 1.1 1 0 0 1 1 1 0 Nuclear protein MDM1 DNA_pol_phi PF04931.13 OQR95332.1 - 0.23 9.5 23.7 0.26 9.3 23.7 1.1 1 0 0 1 1 1 0 DNA polymerase phi BUD22 PF09073.10 OQR95332.1 - 1.5 8.1 17.6 1.6 8.0 17.6 1.1 1 0 0 1 1 1 0 BUD22 SDA1 PF05285.12 OQR95332.1 - 1.9 7.9 19.4 2.2 7.6 19.4 1.2 1 0 0 1 1 1 0 SDA1 Mpp10 PF04006.12 OQR95332.1 - 3.6 5.9 19.2 4.2 5.7 19.2 1.1 1 0 0 1 1 1 0 Mpp10 protein Presenilin PF01080.17 OQR95332.1 - 5.7 5.6 5.5 6 5.5 5.5 1.1 1 0 0 1 1 1 0 Presenilin LAP1C PF05609.12 OQR95332.1 - 6.4 5.7 8.4 7.8 5.5 8.4 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Nop14 PF04147.12 OQR95332.1 - 6.6 4.8 20.6 7.1 4.7 20.6 1.1 1 0 0 1 1 1 0 Nop14-like family His_Phos_1 PF00300.22 OQR95333.1 - 4.4e-47 160.3 0.0 1e-46 159.1 0.0 1.6 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Sel1 PF08238.12 OQR95333.1 - 7.8e-39 131.2 19.5 5.6e-11 42.7 0.2 8.3 8 0 0 8 8 8 5 Sel1 repeat TPR_6 PF13174.6 OQR95333.1 - 0.00045 20.7 3.5 13 6.7 0.0 6.6 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_2 PF07719.17 OQR95334.1 - 1.5e-32 109.1 7.9 0.0071 16.4 0.0 10.1 10 0 0 10 10 10 8 Tetratricopeptide repeat TPR_1 PF00515.28 OQR95334.1 - 3.1e-31 105.9 11.6 9.1e-06 25.3 0.0 9.3 10 0 0 10 10 10 7 Tetratricopeptide repeat TPR_12 PF13424.6 OQR95334.1 - 1.2e-21 76.7 6.0 0.00043 20.5 0.0 7.5 4 2 2 7 7 7 5 Tetratricopeptide repeat TPR_8 PF13181.6 OQR95334.1 - 7e-21 72.6 5.2 0.0014 18.7 0.0 8.1 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_16 PF13432.6 OQR95334.1 - 1.4e-18 67.3 0.1 0.0089 16.7 0.0 7.1 5 1 2 7 7 7 5 Tetratricopeptide repeat TPR_19 PF14559.6 OQR95334.1 - 2.2e-18 66.5 1.4 0.0009 19.7 0.0 7.1 5 2 2 7 7 7 3 Tetratricopeptide repeat TPR_14 PF13428.6 OQR95334.1 - 1.4e-16 59.8 3.0 0.061 14.2 0.0 8.3 5 3 5 10 10 10 4 Tetratricopeptide repeat TPR_17 PF13431.6 OQR95334.1 - 2.4e-13 49.5 11.6 0.001 19.3 0.0 9.1 10 0 0 10 10 10 2 Tetratricopeptide repeat TPR_6 PF13174.6 OQR95334.1 - 3.4e-11 43.0 3.6 0.49 11.1 0.0 8.1 9 0 0 9 9 9 2 Tetratricopeptide repeat TPR_9 PF13371.6 OQR95334.1 - 2e-10 40.6 0.6 0.037 14.2 0.1 5.0 3 2 1 5 5 5 3 Tetratricopeptide repeat TPR_7 PF13176.6 OQR95334.1 - 1.9e-09 36.9 7.1 1.2 9.4 0.0 8.4 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_11 PF13414.6 OQR95334.1 - 3.1e-07 29.9 9.8 0.13 12.0 0.1 6.3 4 2 2 6 6 6 2 TPR repeat TPR_15 PF13429.6 OQR95334.1 - 4.9e-05 22.7 0.4 0.04 13.1 0.1 4.0 2 1 0 3 3 3 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 OQR95334.1 - 0.00014 21.8 1.3 1.8 8.7 0.1 4.7 5 0 0 5 5 5 1 Fis1 C-terminal tetratricopeptide repeat ANAPC3 PF12895.7 OQR95334.1 - 0.00043 20.5 13.3 1.5 9.1 0.6 5.0 2 2 3 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.6 OQR95334.1 - 0.00065 19.5 4.1 0.6 10.1 0.2 5.3 5 0 0 5 5 5 1 Tetratricopeptide repeat Loricrin PF15847.5 OQR95335.1 - 2.1 7.4 61.0 2.5 7.1 61.0 1.1 1 0 0 1 1 1 0 Major keratinocyte cell envelope protein His_Phos_1 PF00300.22 OQR95336.1 - 1.8e-42 145.3 0.0 3.5e-42 144.3 0.0 1.4 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Metallophos PF00149.28 OQR95336.1 - 1.1e-32 114.2 0.1 3e-32 112.8 0.1 1.8 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 OQR95336.1 - 0.0065 16.9 0.1 0.016 15.6 0.1 1.6 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain Noc2 PF03715.13 OQR95338.1 - 9e-79 264.8 9.3 1e-78 264.6 8.1 1.7 2 0 0 2 2 2 1 Noc2p family Nop14 PF04147.12 OQR95338.1 - 0.00073 17.9 1.2 0.00073 17.9 1.2 3.1 2 1 0 3 3 3 1 Nop14-like family CNDH2_C PF16858.5 OQR95338.1 - 1.7 8.5 18.7 0.28 11.0 5.4 2.4 2 0 0 2 2 2 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term SDA1 PF05285.12 OQR95338.1 - 2.1 7.7 34.3 0.13 11.7 11.0 2.4 2 0 0 2 2 2 0 SDA1 Ank_2 PF12796.7 OQR95340.1 - 3.5e-28 98.0 5.4 4.7e-08 33.5 0.0 6.0 2 1 5 7 7 7 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQR95340.1 - 1.4e-20 73.4 4.4 0.011 16.3 0.0 9.2 6 4 0 8 8 8 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 OQR95340.1 - 6.8e-17 61.3 3.5 0.13 12.6 0.0 10.0 5 3 6 11 11 11 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQR95340.1 - 6.1e-15 53.8 1.2 3.6 8.5 0.0 10.1 8 3 2 10 10 10 3 Ankyrin repeat DUF249 PF03158.13 OQR95340.1 - 3.1e-05 23.8 6.4 0.0018 18.0 0.2 3.8 4 2 0 4 4 4 2 Multigene family 530 protein Ank PF00023.30 OQR95340.1 - 6.9e-05 23.1 0.2 12 6.5 0.0 6.8 4 3 2 6 6 6 1 Ankyrin repeat Tn7_Tnp_TnsA_C PF08721.11 OQR95340.1 - 0.055 14.1 0.0 4.2 8.1 0.0 3.5 3 0 0 3 3 3 0 TnsA endonuclease C terminal DUF1843 PF08898.10 OQR95340.1 - 0.15 12.6 0.1 18 5.9 0.0 3.5 4 0 0 4 4 4 0 Domain of unknown function (DUF1843) Peptidase_C1 PF00112.23 OQR95341.1 - 6.3e-61 206.2 8.0 9.8e-61 205.6 8.0 1.2 1 0 0 1 1 1 1 Papain family cysteine protease PT PF04886.12 OQR95341.1 - 2.4e-10 39.8 24.6 2.2e-06 27.1 24.6 2.4 1 1 0 1 1 1 1 PT repeat Peptidase_C1_2 PF03051.15 OQR95341.1 - 0.0011 17.9 0.6 0.21 10.3 0.0 2.2 2 0 0 2 2 2 2 Peptidase C1-like family Trypan_PARP PF05887.11 OQR95341.1 - 3.2 7.7 15.5 4.5 7.3 14.7 1.6 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) Peptidase_C1 PF00112.23 OQR95342.1 - 8e-62 209.2 13.6 1.4e-61 208.4 13.6 1.4 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.15 OQR95342.1 - 5.3e-05 22.2 1.3 0.09 11.5 0.1 2.1 2 0 0 2 2 2 2 Peptidase C1-like family FHA PF00498.26 OQR95343.1 - 1.9e-05 24.9 0.0 3.9e-05 23.9 0.0 1.6 1 1 0 1 1 1 1 FHA domain DUF4476 PF14771.6 OQR95345.1 - 0.024 14.9 0.3 0.058 13.7 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4476) AP_endonuc_2 PF01261.24 OQR95346.1 - 1.8e-05 24.3 1.1 2.9e-05 23.6 1.1 1.3 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel Pkinase PF00069.25 OQR95347.1 - 7.8e-19 68.1 0.1 1.1e-18 67.5 0.0 1.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQR95347.1 - 3.4e-18 65.9 0.0 4e-18 65.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PspA_IM30 PF04012.12 OQR95347.1 - 0.0011 18.6 0.4 0.0017 17.9 0.4 1.2 1 0 0 1 1 1 1 PspA/IM30 family ADIP PF11559.8 OQR95347.1 - 0.0066 16.6 2.0 0.011 15.9 2.0 1.3 1 0 0 1 1 1 1 Afadin- and alpha -actinin-Binding NPV_P10 PF05531.12 OQR95347.1 - 0.018 15.5 1.4 0.029 14.8 0.5 1.8 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Tropomyosin_1 PF12718.7 OQR95347.1 - 0.023 14.8 1.1 0.035 14.2 1.1 1.2 1 0 0 1 1 1 0 Tropomyosin like Kdo PF06293.14 OQR95347.1 - 0.056 12.8 0.2 0.22 10.8 0.0 1.8 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family LPP PF04728.13 OQR95347.1 - 0.062 13.7 0.9 0.19 12.2 0.3 2.1 2 0 0 2 2 2 0 Lipoprotein leucine-zipper Helo_like_N PF17111.5 OQR95347.1 - 0.08 12.3 0.9 0.13 11.6 0.9 1.3 1 0 0 1 1 1 0 Fungal N-terminal domain of STAND proteins Laminin_II PF06009.12 OQR95347.1 - 0.085 12.9 0.4 0.16 12.0 0.1 1.6 2 0 0 2 2 2 0 Laminin Domain II betaPIX_CC PF16523.5 OQR95347.1 - 0.1 12.4 0.1 0.23 11.3 0.1 1.6 1 0 0 1 1 1 0 betaPIX coiled coil DUF4988 PF16378.5 OQR95347.1 - 0.11 12.2 0.7 0.18 11.5 0.2 1.6 2 0 0 2 2 2 0 Domain of unknown function PHD_Oberon PF07227.11 OQR95347.1 - 0.11 12.4 0.0 0.2 11.5 0.0 1.3 1 0 0 1 1 1 0 PHD - plant homeodomain finger protein DUF4140 PF13600.6 OQR95347.1 - 0.14 12.6 0.6 0.29 11.6 0.6 1.5 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) Ribosomal_S3Ae PF01015.18 OQR95348.1 - 2.5e-91 304.7 3.0 3e-91 304.5 3.0 1.0 1 0 0 1 1 1 1 Ribosomal S3Ae family IQ PF00612.27 OQR95349.1 - 7.5e-30 99.9 62.5 0.0007 19.2 0.9 13.0 12 0 0 12 12 12 11 IQ calmodulin-binding motif Exo_endo_phos PF03372.23 OQR95349.1 - 1e-22 80.8 0.1 3.9e-22 78.9 0.1 2.0 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family zf-C6H2 PF15801.5 OQR95349.1 - 4.5e-10 39.7 0.7 1.1e-09 38.4 0.7 1.7 1 0 0 1 1 1 1 zf-MYND-like zinc finger, mRNA-binding BolA PF01722.18 OQR95349.1 - 0.0061 16.8 0.0 0.044 14.1 0.0 2.5 2 0 0 2 2 2 1 BolA-like protein Exo_endo_phos_2 PF14529.6 OQR95349.1 - 0.077 12.8 0.0 0.25 11.2 0.0 1.9 1 0 0 1 1 1 0 Endonuclease-reverse transcriptase ADH_zinc_N_2 PF13602.6 OQR95350.1 - 2e-22 80.7 0.0 4.3e-22 79.6 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 OQR95350.1 - 8.4e-09 35.3 0.0 8.4e-09 35.3 0.0 2.4 2 1 1 3 3 3 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 OQR95350.1 - 7.3e-07 29.2 0.0 1.6e-06 28.1 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Pkinase PF00069.25 OQR95351.1 - 3.3e-38 131.5 0.1 8.8e-38 130.2 0.1 1.7 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQR95351.1 - 1.5e-22 80.2 0.3 3.7e-22 78.8 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase Ion_trans PF00520.31 OQR95351.1 - 1.2e-19 70.5 15.7 2.2e-19 69.7 15.7 1.4 1 0 0 1 1 1 1 Ion transport protein cNMP_binding PF00027.29 OQR95351.1 - 4.3e-11 42.7 0.1 1.4e-10 41.1 0.1 1.8 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Ion_trans_2 PF07885.16 OQR95351.1 - 1.7e-10 40.7 6.2 4.9e-10 39.2 6.2 1.9 1 1 0 1 1 1 1 Ion channel Pkinase_fungal PF17667.1 OQR95351.1 - 0.00025 19.9 0.0 0.00055 18.8 0.0 1.5 1 0 0 1 1 1 1 Fungal protein kinase Histone PF00125.24 OQR95352.1 - 9.1e-40 136.1 3.5 1.7e-39 135.2 3.5 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 SGS PF05002.15 OQR95352.1 - 5.1e-29 100.2 6.4 6.5e-29 99.9 4.7 2.1 2 0 0 2 2 2 1 SGS domain CS PF04969.16 OQR95352.1 - 1.1e-15 58.4 0.2 2.2e-15 57.4 0.2 1.6 1 0 0 1 1 1 1 CS domain TPR_1 PF00515.28 OQR95352.1 - 3.6e-14 51.9 2.6 2.2e-06 27.2 0.3 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 OQR95352.1 - 8.1e-11 41.4 2.3 1.4e-07 31.0 0.4 2.7 1 1 1 2 2 2 2 TPR repeat TPR_2 PF07719.17 OQR95352.1 - 1.6e-10 40.2 12.8 7.9e-05 22.5 0.4 4.6 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 OQR95352.1 - 1.6e-06 27.9 1.9 0.028 14.6 0.2 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.6 OQR95352.1 - 5.9e-05 23.1 1.2 0.00014 22.0 1.2 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_19 PF14559.6 OQR95352.1 - 6.2e-05 23.4 4.5 6.2e-05 23.4 4.5 2.8 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.6 OQR95352.1 - 0.00027 21.1 1.6 0.013 15.8 0.8 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 OQR95352.1 - 0.0034 18.0 3.5 0.0034 18.0 3.5 3.1 2 1 0 3 3 3 1 Tetratricopeptide repeat TFIID-31kDa PF02291.15 OQR95352.1 - 0.0062 16.6 0.1 0.015 15.3 0.1 1.6 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit CENP-T_C PF15511.6 OQR95352.1 - 0.0082 16.3 0.1 0.02 15.0 0.1 1.6 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold ANAPC3 PF12895.7 OQR95352.1 - 0.0094 16.2 1.1 0.029 14.6 1.1 1.8 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 CENP-S PF15630.6 OQR95352.1 - 0.015 15.6 0.2 0.038 14.4 0.2 1.6 1 0 0 1 1 1 0 CENP-S protein TAF PF02969.17 OQR95352.1 - 0.038 14.2 0.7 0.085 13.0 0.7 1.6 1 0 0 1 1 1 0 TATA box binding protein associated factor (TAF) TPR_14 PF13428.6 OQR95352.1 - 0.052 14.4 10.7 0.22 12.4 1.9 3.8 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.6 OQR95352.1 - 0.065 13.3 3.0 0.13 12.3 0.1 2.9 3 0 0 3 3 2 0 Tetratricopeptide repeat Claudin_2 PF13903.6 OQR95353.1 - 0.033 14.0 0.1 0.033 14.0 0.1 2.5 2 1 0 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction COX14 PF14880.6 OQR95353.1 - 0.15 11.9 0.2 12 5.8 0.0 2.6 2 0 0 2 2 2 0 Cytochrome oxidase c assembly Clc-like PF07062.12 OQR95353.1 - 0.15 11.5 20.3 2.5 7.5 0.0 2.8 2 1 0 2 2 2 0 Clc-like TTL PF03133.15 OQR95354.1 - 2.7e-07 30.0 0.0 4e-07 29.4 0.0 1.2 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family EGF_Tenascin PF18720.1 OQR95354.1 - 0.0016 18.4 9.5 0.0032 17.5 9.5 1.5 1 0 0 1 1 1 1 Tenascin EGF domain ATPgrasp_YheCD PF14398.6 OQR95354.1 - 0.026 13.8 0.0 0.037 13.3 0.0 1.2 1 0 0 1 1 1 0 YheC/D like ATP-grasp Dala_Dala_lig_C PF07478.13 OQR95354.1 - 0.17 11.4 0.0 0.28 10.7 0.0 1.3 1 0 0 1 1 1 0 D-ala D-ala ligase C-terminus EB PF01683.18 OQR95354.1 - 0.51 10.7 10.7 0.96 9.8 10.7 1.7 1 1 0 1 1 1 0 EB module EGF PF00008.27 OQR95354.1 - 0.83 10.0 11.8 2.1 8.7 11.8 1.7 1 0 0 1 1 1 0 EGF-like domain EGF_2 PF07974.13 OQR95354.1 - 4.2 7.8 24.8 0.17 12.3 18.3 2.0 2 0 0 2 2 2 0 EGF-like domain AA_kinase PF00696.28 OQR95355.1 - 2e-41 142.2 0.6 4.6e-41 141.0 0.6 1.6 1 0 0 1 1 1 1 Amino acid kinase family Homoserine_dh PF00742.19 OQR95355.1 - 1.3e-34 119.6 0.0 2.6e-34 118.6 0.0 1.6 1 0 0 1 1 1 1 Homoserine dehydrogenase ACT_7 PF13840.6 OQR95355.1 - 3.4e-06 26.8 0.2 0.025 14.4 0.0 3.8 3 0 0 3 3 3 2 ACT domain NAD_binding_3 PF03447.16 OQR95355.1 - 6.1e-06 26.9 3.1 0.00047 20.8 0.0 3.5 3 0 0 3 3 3 1 Homoserine dehydrogenase, NAD binding domain DUF2007 PF09413.10 OQR95355.1 - 0.044 14.0 1.0 10 6.4 0.0 4.3 5 0 0 5 5 5 0 Putative prokaryotic signal transducing protein TROVE PF05731.11 OQR95355.1 - 0.15 11.1 0.0 0.47 9.4 0.0 1.7 2 0 0 2 2 2 0 TROVE domain TTL PF03133.15 OQR95356.1 - 3.9e-71 239.6 1.8 1.1e-42 146.2 0.0 2.2 2 0 0 2 2 2 2 Tubulin-tyrosine ligase family EGF_2 PF07974.13 OQR95356.1 - 0.0027 18.1 13.5 0.0052 17.1 13.5 1.5 1 0 0 1 1 1 1 EGF-like domain ATPgrasp_YheCD PF14398.6 OQR95356.1 - 0.0078 15.5 0.0 0.018 14.3 0.0 1.5 1 0 0 1 1 1 1 YheC/D like ATP-grasp EGF_Tenascin PF18720.1 OQR95356.1 - 0.011 15.7 7.4 0.031 14.3 7.4 1.8 1 0 0 1 1 1 0 Tenascin EGF domain Dala_Dala_lig_C PF07478.13 OQR95356.1 - 0.08 12.5 0.0 0.14 11.6 0.0 1.3 1 0 0 1 1 1 0 D-ala D-ala ligase C-terminus EB PF01683.18 OQR95356.1 - 0.088 13.1 3.9 0.17 12.2 3.9 1.5 1 0 0 1 1 1 0 EB module I-EGF_1 PF18372.1 OQR95356.1 - 0.15 12.2 5.5 0.36 11.0 5.5 1.7 1 0 0 1 1 1 0 Integrin beta epidermal growth factor like domain 1 hEGF PF12661.7 OQR95356.1 - 0.86 10.3 5.0 1.9 9.3 5.0 1.6 1 0 0 1 1 1 0 Human growth factor-like EGF EGF PF00008.27 OQR95356.1 - 8.6 6.8 8.9 20 5.6 8.9 1.6 1 0 0 1 1 1 0 EGF-like domain Ctr PF04145.15 OQR95357.1 - 1.2e-14 55.2 14.0 2.5e-12 47.6 14.0 2.2 1 1 0 1 1 1 1 Ctr copper transporter family HMA PF00403.26 OQR95357.1 - 3.7e-07 30.5 0.3 6.9e-07 29.6 0.3 1.5 1 0 0 1 1 1 1 Heavy-metal-associated domain YHS PF04945.13 OQR95357.1 - 0.01 15.9 0.1 0.084 13.0 0.0 2.6 3 0 0 3 3 3 0 YHS domain Ephrin_rec_like PF07699.13 OQR95358.1 - 1.1e-06 28.3 49.5 0.00019 21.1 3.3 8.1 5 2 2 7 7 7 4 Putative ephrin-receptor like SKG6 PF08693.10 OQR95358.1 - 0.0047 16.3 5.9 0.0096 15.3 5.9 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain DUF3377 PF11857.8 OQR95358.1 - 0.04 13.8 1.7 0.089 12.7 1.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) NCD3G PF07562.14 OQR95358.1 - 0.62 10.1 41.0 0.11 12.5 2.6 7.2 5 2 1 6 6 6 0 Nine Cysteines Domain of family 3 GPCR TTL PF03133.15 OQR95359.1 - 6.5e-26 91.1 0.1 1.1e-25 90.3 0.1 1.4 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family EGF_2 PF07974.13 OQR95359.1 - 0.00029 21.1 14.0 0.00064 20.0 14.0 1.6 1 0 0 1 1 1 1 EGF-like domain hEGF PF12661.7 OQR95359.1 - 0.15 12.8 7.5 0.33 11.6 7.5 1.7 1 0 0 1 1 1 0 Human growth factor-like EGF EGF_Tenascin PF18720.1 OQR95359.1 - 0.16 12.1 7.4 0.32 11.1 7.4 1.5 1 0 0 1 1 1 0 Tenascin EGF domain EB PF01683.18 OQR95359.1 - 0.18 12.1 8.1 0.2 11.9 7.4 1.5 1 1 0 1 1 1 0 EB module I-EGF_1 PF18372.1 OQR95359.1 - 0.23 11.6 5.3 0.49 10.5 5.3 1.6 1 0 0 1 1 1 0 Integrin beta epidermal growth factor like domain 1 DUF1206 PF06724.11 OQR95359.1 - 0.31 11.1 2.1 0.23 11.6 0.2 1.7 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1206) Pkinase PF00069.25 OQR95360.1 - 4e-47 160.8 0.0 6.2e-47 160.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQR95360.1 - 1.9e-41 142.0 0.0 3.1e-41 141.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase LRR_4 PF12799.7 OQR95360.1 - 2.4e-05 24.6 13.0 0.021 15.2 0.6 4.6 4 0 0 4 4 4 2 Leucine Rich repeats (2 copies) Pkinase_fungal PF17667.1 OQR95360.1 - 5.6e-05 22.1 0.1 0.00066 18.6 0.0 2.0 2 0 0 2 2 2 1 Fungal protein kinase Glycophorin_A PF01102.18 OQR95360.1 - 0.014 15.6 0.3 0.014 15.6 0.3 1.9 1 1 1 2 2 2 0 Glycophorin A DUF4501 PF14946.6 OQR95360.1 - 0.024 14.7 0.8 0.024 14.7 0.8 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4501) DUF4064 PF13273.6 OQR95360.1 - 0.036 14.4 0.2 0.091 13.0 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4064) Otopetrin PF03189.13 OQR95360.1 - 0.042 12.7 0.1 0.042 12.7 0.1 2.1 1 1 0 2 2 2 0 Otopetrin DUF5305 PF17231.2 OQR95360.1 - 0.048 13.0 0.0 0.083 12.3 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5305) LysM PF01476.20 OQR95360.1 - 0.12 12.4 0.2 0.56 10.3 0.2 2.2 1 0 0 1 1 1 0 LysM domain SPX PF03105.19 OQR95360.1 - 0.14 12.0 5.7 0.21 11.5 5.7 1.1 1 0 0 1 1 1 0 SPX domain DUF4366 PF14283.6 OQR95360.1 - 0.46 10.5 0.0 0.46 10.5 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4366) DUF4834 PF16118.5 OQR95360.1 - 0.74 10.8 2.5 1.9 9.5 2.5 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4834) Podoplanin PF05808.11 OQR95360.1 - 4.8 7.3 9.5 0.5 10.4 2.2 2.5 3 0 0 3 3 2 0 Podoplanin Pkinase_Tyr PF07714.17 OQR95361.1 - 1e-08 34.8 0.0 2.4e-08 33.6 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.25 OQR95361.1 - 8.9e-08 31.8 0.0 1.5e-07 31.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Podoplanin PF05808.11 OQR95361.1 - 2.4e-05 24.5 9.9 0.00033 20.8 1.6 2.3 2 0 0 2 2 2 2 Podoplanin T4SS_CagC PF16943.5 OQR95361.1 - 0.0017 18.5 1.2 0.049 13.8 0.0 2.5 2 0 0 2 2 2 1 Cag pathogenicity island, type IV secretory system DUF4366 PF14283.6 OQR95361.1 - 0.007 16.4 0.3 1.4 9.0 0.0 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF4366) TMEM154 PF15102.6 OQR95361.1 - 0.022 14.6 0.4 0.2 11.5 0.0 2.2 2 0 0 2 2 2 0 TMEM154 protein family DUF5305 PF17231.2 OQR95361.1 - 0.026 13.9 0.9 2.7 7.4 0.0 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5305) OppC_N PF12911.7 OQR95361.1 - 0.075 13.0 4.3 1.7 8.7 0.0 3.3 3 1 0 3 3 3 0 N-terminal TM domain of oligopeptide transport permease C DUF4064 PF13273.6 OQR95361.1 - 0.32 11.3 6.0 1.8 8.9 0.1 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF4064) DUF4190 PF13828.6 OQR95361.1 - 0.42 10.4 8.4 0.29 10.9 1.1 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4190) DUF2613 PF11021.8 OQR95361.1 - 1.1 9.4 14.9 0.34 11.0 0.4 4.1 4 0 0 4 4 4 0 Protein of unknown function (DUF2613) FNIP PF05725.12 OQR95361.1 - 1.1 9.5 8.8 13 6.1 2.3 3.1 2 1 0 2 2 2 0 FNIP Repeat RNA_pol_Rpb8 PF03870.15 OQR95362.1 - 2.8e-46 157.2 0.0 3.1e-46 157.0 0.0 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb8 RNA_pol_RpbG PF16992.5 OQR95362.1 - 0.026 14.6 0.0 0.21 11.7 0.0 1.9 2 0 0 2 2 2 0 DNA-directed RNA polymerase, subunit G DUF1764 PF08576.10 OQR95363.1 - 2.6e-22 79.6 4.7 2.6e-22 79.6 4.7 2.0 1 1 1 2 2 2 1 Eukaryotic protein of unknown function (DUF1764) Tup_N PF08581.10 OQR95363.1 - 0.022 15.0 5.2 0.04 14.2 5.2 1.4 1 0 0 1 1 1 0 Tup N-terminal Minor_capsid_3 PF12691.7 OQR95363.1 - 0.2 12.1 2.4 0.54 10.6 2.4 1.7 1 1 0 1 1 1 0 Minor capsid protein from bacteriophage FmdE PF02663.14 OQR95363.1 - 0.37 10.8 4.4 0.51 10.4 4.4 1.3 1 0 0 1 1 1 0 FmdE, Molybdenum formylmethanofuran dehydrogenase operon PA26 PF04636.13 OQR95363.1 - 0.52 9.2 7.1 0.6 9.0 7.1 1.0 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) DUF3584 PF12128.8 OQR95363.1 - 0.9 7.0 13.3 1.1 6.7 13.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Atg14 PF10186.9 OQR95363.1 - 1.1 8.3 10.5 1.3 8.1 10.5 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Fzo_mitofusin PF04799.13 OQR95363.1 - 1.3 8.5 5.1 1.7 8.1 5.1 1.2 1 0 0 1 1 1 0 fzo-like conserved region DUF4407 PF14362.6 OQR95363.1 - 4.2 6.6 9.6 5.3 6.3 9.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Ank_2 PF12796.7 OQR95364.1 - 3.8e-104 341.5 35.9 1.2e-15 57.8 0.1 10.2 1 1 9 11 11 11 11 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQR95364.1 - 9.8e-94 306.6 30.0 1.2e-09 38.5 0.0 16.2 6 6 11 17 17 17 17 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQR95364.1 - 6.9e-71 225.7 30.0 0.0013 19.1 0.0 21.4 22 0 0 22 22 22 14 Ankyrin repeat Ank_5 PF13857.6 OQR95364.1 - 4.1e-70 230.9 40.3 3.6e-08 33.5 0.1 17.5 5 4 13 18 18 18 16 Ankyrin repeats (many copies) Ank PF00023.30 OQR95364.1 - 4.1e-65 213.6 42.7 0.00034 20.9 0.0 20.3 21 0 0 21 21 21 15 Ankyrin repeat DUF249 PF03158.13 OQR95364.1 - 0.0033 17.2 0.9 42 3.8 0.0 5.3 4 3 3 7 7 7 0 Multigene family 530 protein EccE PF11203.8 OQR95364.1 - 0.019 15.3 1.3 0.11 12.8 0.0 2.7 3 0 0 3 3 3 0 Putative type VII ESX secretion system translocon, EccE Sacchrp_dh_NADP PF03435.18 OQR95364.1 - 0.12 12.6 0.0 0.12 12.6 0.0 4.0 5 1 0 5 5 5 0 Saccharopine dehydrogenase NADP binding domain GatB_Yqey PF02637.18 OQR95365.1 - 0.09 12.7 0.1 0.2 11.6 0.1 1.5 1 0 0 1 1 1 0 GatB domain Myc_target_1 PF15179.6 OQR95365.1 - 0.11 12.4 0.2 0.24 11.3 0.2 1.5 1 0 0 1 1 1 0 Myc target protein 1 EF-hand_1 PF00036.32 OQR95365.1 - 0.12 12.0 0.1 0.3 10.7 0.1 1.7 1 0 0 1 1 1 0 EF hand COX1 PF00115.20 OQR95365.1 - 1.4 7.7 8.1 1.3 7.8 5.7 1.9 2 0 0 2 2 2 0 Cytochrome C and Quinol oxidase polypeptide I DUF4191 PF13829.6 OQR95365.1 - 4.3 6.6 6.0 1.9 7.8 0.0 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4191) MttA_Hcf106 PF02416.16 OQR95365.1 - 9.7 5.6 6.2 1.2 8.5 1.0 2.2 2 0 0 2 2 2 0 mttA/Hcf106 family Pet100 PF09803.9 OQR95367.1 - 1.8e-09 38.0 0.3 1.8e-09 37.9 0.3 1.0 1 0 0 1 1 1 1 Pet100 TRI5 PF06330.11 OQR95367.1 - 0.062 12.2 0.0 0.069 12.0 0.0 1.1 1 0 0 1 1 1 0 Trichodiene synthase (TRI5) Dus PF01207.17 OQR95368.1 - 3.5e-72 243.1 0.1 4.4e-72 242.8 0.1 1.1 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) His_biosynth PF00977.21 OQR95368.1 - 8.3e-08 32.0 0.0 1.3e-07 31.3 0.0 1.2 1 0 0 1 1 1 1 Histidine biosynthesis protein ThiG PF05690.14 OQR95368.1 - 4.4e-06 26.2 0.1 3.3e-05 23.3 0.0 2.0 1 1 1 2 2 2 1 Thiazole biosynthesis protein ThiG NMO PF03060.15 OQR95368.1 - 1.6e-05 24.5 0.0 2.7e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 Nitronate monooxygenase DHO_dh PF01180.21 OQR95368.1 - 6.6e-05 22.3 0.1 0.31 10.2 0.0 2.1 2 0 0 2 2 2 2 Dihydroorotate dehydrogenase TMP-TENI PF02581.17 OQR95368.1 - 0.019 14.3 0.0 0.035 13.4 0.0 1.4 1 0 0 1 1 1 0 Thiamine monophosphate synthase G3P_antiterm PF04309.12 OQR95368.1 - 0.12 11.8 0.0 0.2 11.1 0.0 1.3 1 0 0 1 1 1 0 Glycerol-3-phosphate responsive antiterminator IMPDH PF00478.25 OQR95368.1 - 0.21 10.5 0.0 0.35 9.8 0.0 1.2 1 0 0 1 1 1 0 IMP dehydrogenase / GMP reductase domain DAGK_cat PF00781.24 OQR95369.1 - 2.1e-30 104.9 0.1 3.3e-30 104.3 0.1 1.3 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain Tim17 PF02466.19 OQR95370.1 - 1.5e-29 102.6 3.2 2e-29 102.2 3.2 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family ABC2_membrane PF01061.24 OQR95371.1 - 1.1e-35 123.0 24.3 1.9e-35 122.2 24.3 1.4 1 0 0 1 1 1 1 ABC-2 type transporter PDR_CDR PF06422.12 OQR95371.1 - 7.1e-06 25.8 0.6 7.1e-06 25.8 0.6 2.1 2 0 0 2 2 2 1 CDR ABC transporter AAA_21 PF13304.6 OQR95371.1 - 0.0099 15.7 0.0 0.017 14.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system PDR_assoc PF08370.11 OQR95371.1 - 0.018 14.8 0.2 0.018 14.8 0.2 3.3 3 0 0 3 3 3 0 Plant PDR ABC transporter associated AAA_18 PF13238.6 OQR95372.1 - 8.4e-06 26.4 0.0 2.1e-05 25.1 0.0 1.7 2 0 0 2 2 2 1 AAA domain dNK PF01712.19 OQR95372.1 - 0.00043 20.2 1.8 0.0017 18.2 1.8 2.0 1 1 0 1 1 1 1 Deoxynucleoside kinase AAA_28 PF13521.6 OQR95372.1 - 0.0011 19.2 0.0 0.0026 18.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 OQR95372.1 - 0.033 14.3 0.0 0.074 13.2 0.0 1.6 1 1 0 1 1 1 0 AAA domain Lon_C PF05362.13 OQR95373.1 - 1.3e-72 243.6 0.2 2.3e-72 242.8 0.2 1.4 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain LON_substr_bdg PF02190.16 OQR95373.1 - 4.8e-36 124.6 0.1 4.8e-36 124.6 0.1 2.3 1 1 1 2 2 1 1 ATP-dependent protease La (LON) substrate-binding domain AAA PF00004.29 OQR95373.1 - 2.2e-22 79.9 0.2 1.2e-21 77.5 0.0 2.3 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) ChlI PF13541.6 OQR95373.1 - 6.6e-07 29.2 0.0 1.6e-06 28.0 0.0 1.7 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase AAA_2 PF07724.14 OQR95373.1 - 5.7e-06 26.5 0.0 2.1e-05 24.7 0.0 1.9 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 OQR95373.1 - 3e-05 24.0 0.0 6.3e-05 23.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 OQR95373.1 - 5.7e-05 23.4 1.0 0.0023 18.2 0.1 3.5 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 OQR95373.1 - 0.00015 22.2 1.1 0.0035 17.8 0.0 2.8 2 1 0 2 2 2 1 AAA ATPase domain AAA_PrkA PF08298.11 OQR95373.1 - 0.00036 19.6 0.0 0.00097 18.1 0.0 1.6 2 0 0 2 2 2 1 PrkA AAA domain AAA_18 PF13238.6 OQR95373.1 - 0.00043 20.8 1.2 0.0088 16.6 0.1 2.9 3 0 0 3 3 3 1 AAA domain RuvB_N PF05496.12 OQR95373.1 - 0.0011 18.7 0.0 0.0056 16.4 0.0 2.3 2 1 0 2 2 1 1 Holliday junction DNA helicase RuvB P-loop domain IstB_IS21 PF01695.17 OQR95373.1 - 0.0059 16.4 0.0 0.015 15.0 0.0 1.7 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_23 PF13476.6 OQR95373.1 - 0.015 15.8 3.1 4.6 7.7 0.0 2.5 2 1 0 2 2 2 0 AAA domain AAA_14 PF13173.6 OQR95373.1 - 0.016 15.3 0.0 0.078 13.0 0.0 2.2 2 0 0 2 2 1 0 AAA domain RsgA_GTPase PF03193.16 OQR95373.1 - 0.02 14.8 0.0 0.071 13.0 0.0 1.9 1 0 0 1 1 1 0 RsgA GTPase RNA_helicase PF00910.22 OQR95373.1 - 0.049 14.0 0.0 0.17 12.3 0.0 2.0 1 0 0 1 1 1 0 RNA helicase Phage_connect_1 PF05135.13 OQR95373.1 - 0.05 14.1 2.8 0.051 14.1 0.2 2.4 3 0 0 3 3 1 0 Phage gp6-like head-tail connector protein NTPase_1 PF03266.15 OQR95373.1 - 0.056 13.4 0.4 1.2 9.1 0.1 2.9 2 1 1 3 3 3 0 NTPase DUF1493 PF07377.12 OQR95373.1 - 0.058 13.9 2.4 6.1 7.3 0.9 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1493) AAA_7 PF12775.7 OQR95373.1 - 0.069 12.7 0.4 0.16 11.5 0.0 1.8 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_30 PF13604.6 OQR95373.1 - 0.071 12.8 0.0 0.18 11.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain TIP49 PF06068.13 OQR95373.1 - 0.11 11.6 0.1 0.11 11.6 0.1 1.7 2 0 0 2 2 1 0 TIP49 P-loop domain ABC_tran PF00005.27 OQR95373.1 - 0.14 12.7 1.9 0.83 10.2 0.1 2.7 2 0 0 2 2 2 0 ABC transporter F-box-like_2 PF13013.6 OQR95373.1 - 0.16 11.9 0.4 0.92 9.5 0.0 2.5 3 0 0 3 3 2 0 F-box-like domain SKI PF01202.22 OQR95373.1 - 0.18 11.9 0.0 0.18 11.9 0.0 2.6 3 0 0 3 3 3 0 Shikimate kinase 5_3_exonuc PF01367.20 OQR95373.1 - 0.25 11.9 2.9 0.77 10.4 2.9 1.9 1 0 0 1 1 1 0 5'-3' exonuclease, C-terminal SAM fold Exonuc_VII_L PF02601.15 OQR95373.1 - 0.4 10.2 3.5 0.73 9.3 3.5 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit ABC2_membrane PF01061.24 OQR95374.1 - 2.7e-33 115.2 24.8 3.9e-33 114.7 24.8 1.3 1 0 0 1 1 1 1 ABC-2 type transporter PDR_CDR PF06422.12 OQR95374.1 - 2.7e-08 33.6 0.6 6.3e-08 32.4 0.0 2.0 2 0 0 2 2 2 1 CDR ABC transporter PDR_assoc PF08370.11 OQR95374.1 - 0.007 16.1 0.0 0.007 16.1 0.0 3.4 4 0 0 4 4 4 1 Plant PDR ABC transporter associated PEX11 PF05648.14 OQR95375.1 - 1.3e-35 122.9 1.1 1.5e-35 122.7 1.1 1.0 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) ELFV_dehydrog PF00208.21 OQR95376.1 - 5.3e-51 173.7 0.0 1.6e-50 172.1 0.0 1.9 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ELFV_dehydrog_N PF02812.18 OQR95376.1 - 6.9e-39 132.7 0.0 1.5e-38 131.6 0.0 1.6 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain BET PF17035.5 OQR95376.1 - 3e-17 62.5 0.1 9.1e-17 61.0 0.1 1.9 1 0 0 1 1 1 1 Bromodomain extra-terminal - transcription regulation Bromodomain PF00439.25 OQR95376.1 - 2.9e-16 59.3 0.0 9.6e-16 57.6 0.0 2.0 1 0 0 1 1 1 1 Bromodomain Kelch_5 PF13854.6 OQR95376.1 - 2.5e-12 46.5 0.2 0.0021 18.0 0.0 5.6 6 0 0 6 6 6 3 Kelch motif Kelch_1 PF01344.25 OQR95376.1 - 1e-10 41.0 0.8 0.45 10.1 0.0 6.6 6 0 0 6 6 6 3 Kelch motif Kelch_4 PF13418.6 OQR95376.1 - 9.2e-10 38.4 3.3 0.0017 18.3 0.1 5.0 5 0 0 5 5 5 2 Galactose oxidase, central domain Kelch_6 PF13964.6 OQR95376.1 - 1.3e-08 34.8 3.5 0.081 13.3 0.0 5.8 5 0 0 5 5 5 2 Kelch motif Kelch_2 PF07646.15 OQR95376.1 - 0.00013 21.8 0.0 6.1 7.0 0.0 4.7 4 0 0 4 4 4 2 Kelch motif NAD_binding_7 PF13241.6 OQR95376.1 - 0.12 12.8 0.0 0.41 11.1 0.0 1.8 1 0 0 1 1 1 0 Putative NAD(P)-binding DUF4381 PF14316.6 OQR95376.1 - 0.16 12.2 1.2 0.58 10.4 1.2 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) Zip PF02535.22 OQR95376.1 - 0.28 10.4 0.0 0.28 10.4 0.0 1.9 2 0 0 2 2 2 0 ZIP Zinc transporter Kelch_3 PF13415.6 OQR95376.1 - 1.1 9.6 12.6 2.8 8.3 0.2 4.9 6 0 0 6 6 5 0 Galactose oxidase, central domain Peptidase_M16 PF00675.20 OQR95376.1 - 2.9 7.9 5.9 10 6.1 5.7 2.0 2 0 0 2 2 2 0 Insulinase (Peptidase family M16) Ctr PF04145.15 OQR95376.1 - 4.7 7.8 11.8 0.14 12.8 0.3 3.3 3 0 0 3 3 3 0 Ctr copper transporter family Ricin_B_lectin PF00652.22 OQR95378.1 - 3.2e-13 50.0 5.5 4.2e-07 30.3 0.2 2.6 2 1 0 2 2 2 2 Ricin-type beta-trefoil lectin domain CDtoxinA PF03498.14 OQR95378.1 - 0.0017 17.9 0.1 3.1 7.4 0.0 3.3 3 0 0 3 3 3 2 Cytolethal distending toxin A/C domain Glyco_hydro_42 PF02449.15 OQR95378.1 - 0.075 12.4 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 Beta-galactosidase bZIP_Maf PF03131.17 OQR95379.1 - 0.065 13.8 4.9 0.12 12.9 4.9 1.4 1 0 0 1 1 1 0 bZIP Maf transcription factor bZIP_1 PF00170.21 OQR95379.1 - 0.13 12.4 7.5 0.21 11.7 7.5 1.3 1 0 0 1 1 1 0 bZIP transcription factor Cnn_1N PF07989.11 OQR95379.1 - 0.18 12.0 3.8 0.31 11.2 3.8 1.3 1 0 0 1 1 1 0 Centrosomin N-terminal motif 1 Metallophos PF00149.28 OQR95380.1 - 4e-17 63.4 1.6 5.4e-17 63.0 1.6 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Ricin_B_lectin PF00652.22 OQR95381.1 - 1.6e-14 54.2 5.3 2e-14 54.0 5.3 1.0 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.6 OQR95381.1 - 4.1e-09 37.0 6.1 1.3e-05 25.8 1.6 2.1 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain-like CDtoxinA PF03498.14 OQR95381.1 - 0.0035 16.9 1.9 0.0059 16.2 1.9 1.4 1 1 0 1 1 1 1 Cytolethal distending toxin A/C domain Nucleoside_tran PF01733.18 OQR95382.1 - 3.5e-17 62.7 20.1 1.5e-14 54.1 4.8 2.6 2 1 1 3 3 3 2 Nucleoside transporter MFS_1 PF07690.16 OQR95382.1 - 7.3e-05 21.8 42.9 9.1e-05 21.5 39.7 2.0 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF21 PF01595.20 OQR95382.1 - 0.18 11.5 5.7 0.39 10.4 1.9 2.6 2 0 0 2 2 2 0 Cyclin M transmembrane N-terminal domain RRM_1 PF00076.22 OQR95383.1 - 2.4e-24 84.9 0.0 5.7e-24 83.7 0.0 1.7 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CSTF2_hinge PF14327.6 OQR95383.1 - 2.2e-05 24.8 0.1 5.3e-05 23.6 0.1 1.6 1 0 0 1 1 1 1 Hinge domain of cleavage stimulation factor subunit 2 RRM_7 PF16367.5 OQR95383.1 - 0.0029 17.7 0.0 0.0054 16.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif RRM_occluded PF16842.5 OQR95383.1 - 0.0098 15.7 0.0 0.028 14.3 0.0 1.7 1 1 0 1 1 1 1 Occluded RNA-recognition motif MutS_V PF00488.21 OQR95384.1 - 2.4e-73 246.2 0.7 5e-73 245.1 0.7 1.5 1 0 0 1 1 1 1 MutS domain V MutS_I PF01624.20 OQR95384.1 - 1.9e-34 118.3 0.0 5.5e-34 116.8 0.0 1.8 2 0 0 2 2 2 1 MutS domain I MutS_III PF05192.18 OQR95384.1 - 2.6e-34 119.1 3.1 1.3e-32 113.6 3.2 2.6 2 0 0 2 2 2 1 MutS domain III MutS_II PF05188.17 OQR95384.1 - 2.2e-11 44.2 0.2 2.5e-10 40.8 0.2 2.6 1 1 0 1 1 1 1 MutS domain II MutS_IV PF05190.18 OQR95384.1 - 1.2e-09 38.4 0.0 3.6e-09 36.8 0.0 1.9 1 0 0 1 1 1 1 MutS family domain IV LIP1 PF15904.5 OQR95384.1 - 2.4 8.6 5.7 5.5 7.4 0.2 3.6 3 0 0 3 3 3 0 LKB1 serine/threonine kinase interacting protein 1 Mlo PF03094.15 OQR95385.1 - 0.00021 19.8 1.7 0.00021 19.8 1.7 2.0 1 1 1 2 2 2 1 Mlo family DUF2634 PF10934.8 OQR95385.1 - 0.14 12.3 2.0 0.22 11.7 0.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2634) TMEM144 PF07857.12 OQR95386.1 - 1.7e-62 211.4 4.0 6.1e-62 209.5 4.0 1.7 1 1 0 1 1 1 1 Transmembrane family, TMEM144 of transporters Sugar_transport PF06800.12 OQR95386.1 - 2.1e-08 33.8 6.7 2.9e-06 26.8 0.0 2.4 2 1 0 2 2 2 2 Sugar transport protein DMT_YdcZ PF04657.13 OQR95386.1 - 0.0063 16.8 20.5 0.2 12.0 9.4 2.8 2 1 0 2 2 2 2 Putative inner membrane exporter, YdcZ 7tm_1 PF00001.21 OQR95386.1 - 0.08 12.2 0.0 0.16 11.3 0.0 1.4 1 0 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) Phage_holin_5_2 PF16079.5 OQR95386.1 - 0.48 10.8 7.3 6.2 7.2 0.2 3.4 3 1 0 3 3 3 0 Phage holin family Hol44, in holin superfamily V La PF05383.17 OQR95387.1 - 8.5e-18 64.2 0.0 1.4e-17 63.5 0.0 1.4 1 0 0 1 1 1 1 La domain RRM_1 PF00076.22 OQR95387.1 - 0.00014 21.7 0.0 0.0042 16.9 0.0 2.7 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SET PF00856.28 OQR95388.1 - 5.2e-11 43.2 1.0 4.2e-10 40.3 0.1 2.5 2 1 0 2 2 2 1 SET domain zf-MYND PF01753.18 OQR95388.1 - 3.6e-09 36.6 12.8 3.6e-09 36.6 12.8 2.3 2 1 0 2 2 2 1 MYND finger TPR_12 PF13424.6 OQR95388.1 - 0.058 13.7 0.0 0.59 10.5 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat Ank_2 PF12796.7 OQR95389.1 - 2e-66 220.5 26.9 4.3e-17 62.5 0.3 6.3 2 2 5 7 7 7 7 Ankyrin repeats (3 copies) Ank PF00023.30 OQR95389.1 - 1.1e-46 155.3 24.2 0.00014 22.2 0.0 11.2 11 0 0 11 11 11 11 Ankyrin repeat Ank_4 PF13637.6 OQR95389.1 - 8.2e-45 150.6 10.6 3.2e-08 33.9 0.0 9.2 3 3 6 10 10 10 10 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQR95389.1 - 4.2e-42 137.3 15.9 0.0028 18.0 0.0 11.3 11 0 0 11 11 11 10 Ankyrin repeat Ank_5 PF13857.6 OQR95389.1 - 1.2e-35 121.1 19.4 2e-07 31.2 0.2 10.6 3 2 8 11 11 11 9 Ankyrin repeats (many copies) Snapin_Pallidin PF14712.6 OQR95390.1 - 8.2e-11 42.2 6.9 1.4e-10 41.5 6.9 1.3 1 0 0 1 1 1 1 Snapin/Pallidin Asp PF00026.23 OQR95391.1 - 3.8e-76 256.5 0.9 4.5e-76 256.3 0.9 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 OQR95391.1 - 3.1e-06 27.5 0.0 0.0036 17.6 0.0 2.5 1 1 1 2 2 2 2 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 OQR95391.1 - 0.045 14.4 0.0 11 6.7 0.0 2.5 2 1 0 2 2 2 0 Aspartyl protease Sugar_tr PF00083.24 OQR95392.1 - 2.1e-27 96.1 36.8 2.8e-20 72.6 9.7 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 OQR95392.1 - 2.9e-22 79.1 45.9 3.4e-20 72.3 32.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily C2 PF00168.30 OQR95393.1 - 5.6e-15 55.5 0.0 4.8e-13 49.3 0.0 3.7 3 0 0 3 3 3 1 C2 domain DEP PF00610.21 OQR95393.1 - 5.3e-08 32.8 0.0 0.0021 18.1 0.0 3.1 3 0 0 3 3 3 2 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) NapD PF03927.13 OQR95393.1 - 0.042 13.9 0.5 0.16 12.1 0.5 2.0 1 0 0 1 1 1 0 NapD protein FAS_N PF17828.1 OQR95393.1 - 0.19 11.8 0.5 0.89 9.6 0.1 2.2 2 0 0 2 2 2 0 N-terminal domain in fatty acid synthase subunit beta TRP PF06011.12 OQR95394.1 - 2.7e-18 65.9 23.5 5.9e-16 58.2 23.5 2.1 1 1 0 1 1 1 1 Transient receptor potential (TRP) ion channel Dynamitin PF04912.14 OQR95395.1 - 5e-56 190.7 24.4 3e-54 184.8 24.4 2.0 1 1 0 1 1 1 1 Dynamitin PLU-1 PF08429.11 OQR95395.1 - 0.0059 15.8 4.9 0.0059 15.8 4.9 1.8 2 0 0 2 2 2 1 PLU-1-like protein Sugarporin_N PF11471.8 OQR95395.1 - 0.06 13.3 1.1 0.21 11.5 0.1 2.5 3 0 0 3 3 3 0 Maltoporin periplasmic N-terminal extension CENP-Q PF13094.6 OQR95395.1 - 0.15 12.2 18.6 1.2 9.3 3.3 3.6 2 1 1 3 3 3 0 CENP-Q, a CENPA-CAD centromere complex subunit CLZ PF16526.5 OQR95395.1 - 0.24 11.8 20.6 1.9 8.9 1.1 5.5 3 2 3 6 6 6 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF3209 PF11483.8 OQR95395.1 - 0.37 11.2 4.9 11 6.5 0.4 3.3 2 1 1 3 3 3 0 Protein of unknown function (DUF3209) FapA PF03961.13 OQR95395.1 - 0.48 9.0 8.7 0.066 11.8 2.0 2.1 2 0 0 2 2 2 0 Flagellar Assembly Protein A DUF2203 PF09969.9 OQR95395.1 - 3 8.6 8.9 0.56 10.9 1.1 3.3 2 1 1 3 3 3 0 Uncharacterized conserved protein (DUF2203) Fib_alpha PF08702.10 OQR95395.1 - 4.9 7.3 19.3 0.54 10.4 6.1 3.2 1 1 1 3 3 3 0 Fibrinogen alpha/beta chain family TRPM_tetra PF16519.5 OQR95395.1 - 5.7 7.1 12.8 14 5.8 0.1 5.2 5 1 1 6 6 6 0 Tetramerisation domain of TRPM XhlA PF10779.9 OQR95395.1 - 8.1 6.7 7.9 5 7.4 0.5 4.0 5 0 0 5 5 5 0 Haemolysin XhlA I-EGF_1 PF18372.1 OQR95396.1 - 1.4 9.1 8.2 1.8 8.7 0.2 3.9 4 0 0 4 4 4 0 Integrin beta epidermal growth factor like domain 1 TBP PF00352.21 OQR95397.1 - 5.9e-37 125.5 0.0 9.5e-23 80.0 0.0 2.1 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.8 OQR95397.1 - 0.00055 20.0 0.0 0.028 14.5 0.0 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF3378) WD40 PF00400.32 OQR95398.1 - 1.1e-22 79.9 14.1 3.9e-05 24.3 0.7 6.6 6 1 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OQR95398.1 - 5.9e-08 32.9 7.2 0.038 14.3 0.0 4.2 3 1 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 OQR95398.1 - 0.00022 20.3 0.5 0.51 9.2 0.0 3.5 2 2 0 2 2 2 2 WD40 region of Ge1, enhancer of mRNA-decapping protein WDCP PF15390.6 OQR95398.1 - 0.011 14.1 0.2 0.017 13.5 0.2 1.1 1 0 0 1 1 1 0 WD repeat and coiled-coil-containing protein family Pribosyltran_N PF13793.6 OQR95400.1 - 8.8e-35 119.1 0.2 7.8e-34 116.1 0.1 2.3 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.6 OQR95400.1 - 1.6e-24 86.9 0.7 5.5e-24 85.2 0.5 2.0 2 0 0 2 2 2 1 Phosphoribosyl synthetase-associated domain Ank_4 PF13637.6 OQR95400.1 - 7.4e-16 58.3 0.0 0.00027 21.4 0.0 4.2 4 0 0 4 4 4 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 OQR95400.1 - 1.6e-14 54.3 0.0 1.5e-08 35.1 0.0 3.2 3 0 0 3 3 3 2 Ankyrin repeats (3 copies) Pribosyltran PF00156.27 OQR95400.1 - 4e-14 52.4 0.7 1.4e-12 47.4 0.2 2.3 2 0 0 2 2 2 1 Phosphoribosyl transferase domain Ank_5 PF13857.6 OQR95400.1 - 6e-11 42.4 0.0 0.00017 21.8 0.0 4.4 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQR95400.1 - 3.8e-10 39.1 0.2 0.012 16.1 0.0 4.5 4 0 0 4 4 4 3 Ankyrin repeat Ank PF00023.30 OQR95400.1 - 3e-09 36.9 3.0 0.00013 22.2 0.0 5.0 5 0 0 5 5 5 2 Ankyrin repeat UPRTase PF14681.6 OQR95400.1 - 0.015 14.7 0.1 0.057 12.9 0.1 1.9 2 0 0 2 2 2 0 Uracil phosphoribosyltransferase PKD_channel PF08016.12 OQR95401.1 - 1.1e-14 54.0 22.6 1.8e-11 43.4 21.7 3.0 2 1 0 2 2 2 2 Polycystin cation channel Ion_trans PF00520.31 OQR95401.1 - 1.2e-06 28.0 22.5 1.9e-06 27.3 22.5 1.3 1 0 0 1 1 1 1 Ion transport protein DUF4032 PF13224.6 OQR95401.1 - 0.17 11.7 0.0 0.52 10.2 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4032) DUF2417 PF10329.9 OQR95401.1 - 0.19 11.1 12.6 0.18 11.2 8.7 2.3 2 0 0 2 2 2 0 Region of unknown function (DUF2417) TPR_2 PF07719.17 OQR95403.1 - 4e-06 26.5 7.7 0.011 15.8 0.0 3.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 OQR95403.1 - 7.9e-06 26.1 6.4 0.00029 21.0 0.0 2.9 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.28 OQR95403.1 - 0.00025 20.8 7.3 0.0055 16.5 0.3 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 OQR95403.1 - 0.0041 17.1 0.3 0.17 12.0 0.0 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.6 OQR95403.1 - 0.0066 16.9 1.0 0.11 13.0 0.1 3.0 1 1 2 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 OQR95403.1 - 0.046 13.9 0.1 0.046 13.9 0.1 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.6 OQR95403.1 - 0.085 13.5 2.1 3.7 8.4 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.6 OQR95403.1 - 0.14 12.0 4.5 0.52 10.2 0.1 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF1771 PF08590.10 OQR95403.1 - 0.81 10.1 7.8 0.76 10.2 0.2 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1771) Glyco_trans_2_3 PF13632.6 OQR95405.1 - 3.1e-18 66.4 0.3 3.4e-17 63.0 0.0 2.7 3 0 0 3 3 3 1 Glycosyl transferase family group 2 Cellulose_synt PF03552.14 OQR95405.1 - 3.1e-14 52.5 7.2 3.2e-10 39.2 0.6 3.4 3 1 1 4 4 4 2 Cellulose synthase PH PF00169.29 OQR95405.1 - 1.1e-09 38.8 0.5 3.3e-09 37.2 0.1 2.1 2 0 0 2 2 2 1 PH domain Glyco_tranf_2_3 PF13641.6 OQR95405.1 - 2.3e-08 34.2 0.0 0.00023 21.1 0.0 2.5 2 0 0 2 2 2 2 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 OQR95405.1 - 6.8e-08 32.5 0.0 0.2 11.5 0.0 3.4 3 0 0 3 3 3 3 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 OQR95405.1 - 4e-05 23.2 0.0 0.0021 17.6 0.0 2.7 3 0 0 3 3 3 1 Glycosyl transferase family 21 zf-C6H2 PF15801.5 OQR95405.1 - 0.00015 22.0 11.1 0.00015 22.0 11.1 3.3 3 1 0 3 3 3 1 zf-MYND-like zinc finger, mRNA-binding PH_11 PF15413.6 OQR95405.1 - 0.0038 17.6 0.2 0.0099 16.3 0.2 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain PH_8 PF15409.6 OQR95405.1 - 0.0059 16.9 0.4 0.12 12.7 0.4 2.5 1 1 0 1 1 1 1 Pleckstrin homology domain Mcp5_PH PF12814.7 OQR95405.1 - 0.089 12.9 0.0 0.17 12.0 0.0 1.4 1 0 0 1 1 1 0 Meiotic cell cortex C-terminal pleckstrin homology Pkinase PF00069.25 OQR95406.1 - 6e-92 307.7 0.0 3.8e-72 242.8 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OQR95406.1 - 3.2e-51 174.1 0.0 3.1e-38 131.6 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 OQR95406.1 - 5.2e-11 42.4 0.0 2.4e-08 33.6 0.0 2.4 2 0 0 2 2 2 2 Kinase-like RIO1 PF01163.22 OQR95406.1 - 1.1e-07 31.6 0.4 0.011 15.4 0.0 3.0 3 0 0 3 3 3 2 RIO1 family NAF PF03822.14 OQR95406.1 - 3.2e-07 30.4 0.1 1.1e-06 28.7 0.1 1.9 1 0 0 1 1 1 1 NAF domain Kdo PF06293.14 OQR95406.1 - 6e-07 29.0 0.2 0.00017 21.0 0.1 2.5 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OQR95406.1 - 1e-06 28.9 0.1 0.033 14.1 0.0 2.6 2 0 0 2 2 2 2 Phosphotransferase enzyme family FTA2 PF13095.6 OQR95406.1 - 0.00093 18.9 0.2 0.49 10.0 0.0 2.5 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Seadorna_VP7 PF07387.11 OQR95406.1 - 0.0015 17.6 0.5 0.67 9.0 0.0 3.3 3 0 0 3 3 3 1 Seadornavirus VP7 Pkinase_fungal PF17667.1 OQR95406.1 - 0.0029 16.5 0.0 0.087 11.6 0.1 2.3 2 0 0 2 2 2 1 Fungal protein kinase Choline_kinase PF01633.20 OQR95406.1 - 0.019 14.6 0.6 0.18 11.4 0.1 2.5 2 1 0 2 2 2 0 Choline/ethanolamine kinase DUF4483 PF14825.6 OQR95407.1 - 3.1e-05 23.8 1.3 0.088 12.6 0.0 3.9 2 1 2 4 4 4 3 Domain of unknown function (DUF4483) IBR PF01485.21 OQR95408.1 - 1.9 8.8 13.0 6.4 7.1 0.6 2.8 2 1 0 2 2 2 0 IBR domain, a half RING-finger domain Defensin_1 PF00323.19 OQR95408.1 - 4.5 7.9 16.1 5.5 7.6 3.9 3.4 3 0 0 3 3 3 0 Mammalian defensin DUF3586 PF12131.8 OQR95410.1 - 1.9 8.7 16.5 2 8.7 3.3 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF3586) PI3_PI4_kinase PF00454.27 OQR95411.1 - 9.8e-40 136.9 0.1 2.5e-29 102.8 0.0 2.4 1 1 1 2 2 2 2 Phosphatidylinositol 3- and 4-kinase DEP PF00610.21 OQR95411.1 - 8e-07 29.0 0.0 2.6e-06 27.4 0.0 1.8 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) DUF4135 PF13575.6 OQR95411.1 - 0.0051 16.2 0.0 0.008 15.5 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4135) RecQ_Zn_bind PF16124.5 OQR95411.1 - 0.016 15.9 0.2 0.063 14.0 0.0 2.1 2 0 0 2 2 2 0 RecQ zinc-binding HSF_DNA-bind PF00447.17 OQR95412.1 - 8.3e-15 55.2 0.0 1.4e-14 54.4 0.0 1.3 1 0 0 1 1 1 1 HSF-type DNA-binding DUF3874 PF12990.7 OQR95412.1 - 0.018 15.3 0.1 0.065 13.6 0.0 1.9 2 0 0 2 2 2 0 Domain of unknonw function from B. Theta Gene description (DUF3874) SAPIS-gp6 PF16722.5 OQR95412.1 - 0.31 11.5 1.9 0.51 10.8 1.9 1.3 1 0 0 1 1 1 0 Pathogenicity island protein gp6 in Staphylococcus Peptidase_M16_M PF16187.5 OQR95414.1 - 1.4e-62 211.6 0.2 4.2e-62 210.0 0.2 1.8 1 0 0 1 1 1 1 Middle or third domain of peptidase_M16 Peptidase_M16 PF00675.20 OQR95414.1 - 1.1e-36 126.1 0.1 5.9e-36 123.7 0.0 2.1 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 OQR95414.1 - 1.1e-27 97.2 0.4 2.5e-19 70.0 0.0 2.9 3 0 0 3 3 3 2 Peptidase M16 inactive domain HSF_DNA-bind PF00447.17 OQR95415.1 - 7.2e-22 77.8 0.0 1.2e-21 77.1 0.0 1.3 1 0 0 1 1 1 1 HSF-type DNA-binding bZIP_1 PF00170.21 OQR95415.1 - 0.0038 17.3 0.4 0.0067 16.5 0.4 1.4 1 0 0 1 1 1 1 bZIP transcription factor MIS13 PF08202.11 OQR95415.1 - 0.011 15.0 1.1 0.016 14.6 1.1 1.2 1 0 0 1 1 1 0 Mis12-Mtw1 protein family DUF2730 PF10805.8 OQR95415.1 - 0.051 13.7 1.3 0.085 13.0 1.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2730) DUF3874 PF12990.7 OQR95415.1 - 0.19 12.1 1.2 0.25 11.7 0.1 1.7 2 0 0 2 2 2 0 Domain of unknonw function from B. Theta Gene description (DUF3874) fn3_PAP PF17808.1 OQR95418.1 - 0.039 14.1 0.4 0.43 10.7 0.1 2.6 3 0 0 3 3 3 0 Fn3-like domain from Purple Acid Phosphatase RCC1 PF00415.18 OQR95419.1 - 1.1e-38 131.6 26.3 6.5e-13 49.1 1.4 7.7 6 2 1 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 OQR95419.1 - 3.3e-29 100.1 25.9 4.5e-10 39.0 1.7 6.7 7 0 0 7 7 7 5 Regulator of chromosome condensation (RCC1) repeat Hira PF07569.11 OQR95419.1 - 2.5 7.8 5.0 19 4.9 0.1 3.1 3 0 0 3 3 3 0 TUP1-like enhancer of split Methyltr_RsmB-F PF01189.17 OQR95420.1 - 3.1e-34 118.4 0.0 3.2e-33 115.1 0.0 2.2 1 1 0 1 1 1 1 16S rRNA methyltransferase RsmB/F FtsJ PF01728.19 OQR95420.1 - 0.0024 18.0 0.0 0.0066 16.6 0.0 1.7 2 0 0 2 2 2 1 FtsJ-like methyltransferase Methyltr_RsmF_N PF17125.5 OQR95420.1 - 0.14 12.6 0.0 0.36 11.3 0.0 1.7 1 0 0 1 1 1 0 N-terminal domain of 16S rRNA methyltransferase RsmF TruD PF01142.18 OQR95421.1 - 4.7e-41 141.0 0.1 6.3e-35 120.8 0.0 2.6 3 0 0 3 3 3 2 tRNA pseudouridine synthase D (TruD) BATS PF06968.13 OQR95422.1 - 2.9e-17 62.6 0.1 2e-16 59.9 0.0 2.4 3 0 0 3 3 3 1 Biotin and Thiamin Synthesis associated domain Cass2 PF14526.6 OQR95422.1 - 2e-14 54.0 0.0 6.1e-14 52.4 0.0 1.9 2 0 0 2 2 2 1 Integron-associated effector binding protein GyrI-like PF06445.15 OQR95422.1 - 2.1e-14 54.1 0.6 8.4e-14 52.2 0.6 1.9 1 1 0 1 1 1 1 GyrI-like small molecule binding domain Radical_SAM PF04055.21 OQR95422.1 - 1.2e-13 51.8 0.7 2.4e-13 50.8 0.7 1.5 1 0 0 1 1 1 1 Radical SAM superfamily EF1_GNE PF00736.19 OQR95423.1 - 7.7e-31 106.1 2.6 1.3e-30 105.5 2.6 1.3 1 0 0 1 1 1 1 EF-1 guanine nucleotide exchange domain EF-1_beta_acid PF10587.9 OQR95423.1 - 0.028 14.9 9.2 0.028 14.9 9.2 2.8 3 0 0 3 3 2 0 Eukaryotic elongation factor 1 beta central acidic region FAM176 PF14851.6 OQR95423.1 - 0.14 11.8 1.7 0.2 11.3 1.7 1.3 1 0 0 1 1 1 0 FAM176 family Red1 PF07964.11 OQR95423.1 - 0.18 10.0 6.2 0.21 9.8 6.2 1.1 1 0 0 1 1 1 0 Rec10 / Red1 AIM3 PF17096.5 OQR95423.1 - 0.43 11.5 10.2 0.92 10.5 10.2 1.5 1 1 0 1 1 1 0 Altered inheritance of mitochondria protein 3 CCDC106 PF15794.5 OQR95423.1 - 0.44 10.2 4.0 0.62 9.7 4.0 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 IFT57 PF10498.9 OQR95423.1 - 0.51 9.2 5.3 0.81 8.6 5.3 1.3 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 PBP1_TM PF14812.6 OQR95423.1 - 1.6 9.2 12.4 0.061 13.7 6.8 1.5 2 0 0 2 2 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DDRGK PF09756.9 OQR95423.1 - 4.9 6.7 8.6 9.4 5.8 8.6 1.5 1 1 0 1 1 1 0 DDRGK domain Pox_Ag35 PF03286.14 OQR95423.1 - 6.1 6.6 17.1 0.2 11.4 11.1 1.5 2 0 0 2 2 2 0 Pox virus Ag35 surface protein Stm1_N PF09598.10 OQR95423.1 - 9.2 7.2 27.1 0.11 13.4 5.0 2.8 2 1 1 3 3 3 0 Stm1 Methyltransf_16 PF10294.9 OQR95424.1 - 2.8e-26 92.3 0.0 4e-26 91.8 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_31 PF13847.6 OQR95424.1 - 0.00014 21.7 0.0 0.00027 20.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OQR95424.1 - 0.00038 21.1 0.0 0.0048 17.6 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 OQR95424.1 - 0.0012 18.4 0.0 0.0021 17.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_23 PF13489.6 OQR95424.1 - 0.0084 16.0 0.0 0.026 14.3 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain GidB PF02527.15 OQR95424.1 - 0.05 12.9 0.1 0.15 11.3 0.0 1.8 2 0 0 2 2 2 0 rRNA small subunit methyltransferase G FRG PF08867.11 OQR95424.1 - 0.091 13.7 0.1 0.26 12.2 0.1 1.7 1 0 0 1 1 1 0 FRG domain PCMT PF01135.19 OQR95424.1 - 0.11 12.2 0.0 0.25 11.1 0.0 1.5 2 0 0 2 2 2 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) DUF4203 PF13886.6 OQR95426.1 - 3.9e-25 88.7 35.7 6.5e-25 88.0 30.7 2.0 2 0 0 2 2 2 2 Domain of unknown function (DUF4203) DctQ PF04290.12 OQR95426.1 - 0.021 14.8 5.6 0.021 14.8 5.6 2.9 2 2 0 2 2 2 0 Tripartite ATP-independent periplasmic transporters, DctQ component Amidase PF01425.21 OQR95427.1 - 4.9e-83 279.6 0.7 6.5e-83 279.2 0.7 1.1 1 0 0 1 1 1 1 Amidase Ras PF00071.22 OQR95429.1 - 8.4e-36 123.0 0.1 1.1e-35 122.6 0.1 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OQR95429.1 - 1.9e-25 89.4 0.1 3.5e-25 88.6 0.1 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OQR95429.1 - 5.6e-10 38.9 0.0 8e-10 38.4 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 OQR95429.1 - 0.0025 17.2 0.1 0.0035 16.7 0.1 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 OQR95429.1 - 0.012 15.7 0.1 0.027 14.5 0.0 1.7 2 0 0 2 2 2 0 50S ribosome-binding GTPase G-alpha PF00503.20 OQR95429.1 - 0.17 11.0 0.2 4.3 6.4 0.1 2.1 1 1 1 2 2 2 0 G-protein alpha subunit DUF4485 PF14846.6 OQR95430.1 - 4.3e-18 65.2 0.1 1.1e-17 63.8 0.1 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4485) Oxysterol_BP PF01237.18 OQR95431.1 - 3.2e-50 171.0 0.4 3.1e-41 141.5 0.0 2.0 1 1 1 2 2 2 2 Oxysterol-binding protein SNARE_assoc PF09335.11 OQR95432.1 - 3.6e-09 37.1 1.3 3.6e-09 37.1 1.3 2.6 3 0 0 3 3 3 1 SNARE associated Golgi protein Ntox43 PF15537.6 OQR95432.1 - 0.15 12.1 0.1 0.28 11.2 0.1 1.3 1 0 0 1 1 1 0 Bacterial toxin 43 Ank_2 PF12796.7 OQR95434.1 - 4.8e-13 49.5 1.5 9.4e-13 48.6 0.6 2.0 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank PF00023.30 OQR95434.1 - 4.9e-13 48.9 5.9 4.9e-06 26.7 0.2 4.4 4 0 0 4 4 4 2 Ankyrin repeat Ank_4 PF13637.6 OQR95434.1 - 7e-11 42.4 0.4 1.4e-09 38.3 0.2 2.8 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQR95434.1 - 7.8e-09 35.1 6.9 0.0001 22.4 0.1 4.5 5 0 0 5 5 5 2 Ankyrin repeat Ank_5 PF13857.6 OQR95434.1 - 1.2e-05 25.5 1.4 0.00024 21.3 0.5 2.8 2 1 1 3 3 3 2 Ankyrin repeats (many copies) SYCE1 PF15233.6 OQR95434.1 - 0.0053 16.8 9.3 0.093 12.8 0.0 2.3 2 0 0 2 2 2 1 Synaptonemal complex central element protein 1 DUF812 PF05667.11 OQR95434.1 - 0.0059 15.6 6.5 0.0059 15.6 6.5 1.9 1 1 1 2 2 2 1 Protein of unknown function (DUF812) CENP-F_leu_zip PF10473.9 OQR95434.1 - 0.073 13.1 6.7 0.087 12.9 5.4 1.8 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 APG6_N PF17675.1 OQR95434.1 - 0.9 10.1 10.2 1.8 9.1 10.2 1.6 1 0 0 1 1 1 0 Apg6 coiled-coil region ubiquitin PF00240.23 OQR95435.1 - 0.02 14.6 0.1 0.034 13.9 0.1 1.3 1 0 0 1 1 1 0 Ubiquitin family DUF4641 PF15483.6 OQR95435.1 - 0.026 13.6 0.0 0.03 13.5 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4641) Rad60-SLD PF11976.8 OQR95435.1 - 0.066 13.0 0.0 0.1 12.5 0.0 1.3 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like RTC PF01137.21 OQR95435.1 - 0.14 11.3 0.0 0.14 11.3 0.0 1.1 1 0 0 1 1 1 0 RNA 3'-terminal phosphate cyclase DSPn PF14671.6 OQR95436.1 - 6.3e-41 140.1 0.2 1.5e-40 138.9 0.0 1.7 2 0 0 2 2 2 1 Dual specificity protein phosphatase, N-terminal half DSPc PF00782.20 OQR95436.1 - 7e-16 58.2 0.0 1.5e-14 54.0 0.0 2.3 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.6 OQR95436.1 - 2.1e-05 24.7 0.0 9.7e-05 22.5 0.0 1.9 2 0 0 2 2 2 1 Inositol hexakisphosphate Y_phosphatase PF00102.27 OQR95436.1 - 2.4e-05 24.0 0.0 5e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 Protein-tyrosine phosphatase TTL PF03133.15 OQR95437.1 - 2.5e-88 296.0 3.1 3.6e-88 295.5 3.1 1.1 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family CS PF04969.16 OQR95437.1 - 1.6e-10 41.9 0.0 3.1e-10 40.9 0.0 1.5 1 0 0 1 1 1 1 CS domain ATPgrasp_YheCD PF14398.6 OQR95437.1 - 4.8e-08 32.6 0.3 3.1e-05 23.4 0.0 3.0 2 1 0 2 2 2 2 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 OQR95437.1 - 8.9e-05 21.9 0.0 0.0025 17.1 0.0 2.4 2 0 0 2 2 2 1 Sugar-transfer associated ATP-grasp GSH-S_ATP PF02955.16 OQR95437.1 - 0.031 13.7 0.0 0.062 12.7 0.0 1.4 1 0 0 1 1 1 0 Prokaryotic glutathione synthetase, ATP-grasp domain LRR_6 PF13516.6 OQR95439.1 - 4.7e-10 38.7 27.0 0.051 13.7 0.1 8.0 8 0 0 8 8 8 5 Leucine Rich repeat LRR_4 PF12799.7 OQR95439.1 - 8.4e-06 26.0 19.0 0.02 15.3 1.5 4.7 2 1 2 4 4 4 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 OQR95439.1 - 0.001 18.8 20.3 0.017 14.8 3.4 5.2 3 3 1 4 4 4 1 Leucine rich repeat LRR_1 PF00560.33 OQR95439.1 - 0.0011 19.2 10.5 55 4.9 0.1 7.3 7 1 0 7 7 7 0 Leucine Rich Repeat LRR_2 PF07723.13 OQR95439.1 - 0.14 12.9 0.6 1.1e+02 3.7 0.2 4.5 5 0 0 5 5 5 0 Leucine Rich Repeat zf-HC5HC2H_2 PF13832.6 OQR95440.1 - 1.8e-14 53.8 8.3 3.5e-14 52.9 8.3 1.4 1 0 0 1 1 1 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 OQR95440.1 - 1.3e-13 51.0 6.0 6.8e-13 48.7 1.9 2.5 2 0 0 2 2 2 1 PHD-like zinc-binding domain Ada3 PF10198.9 OQR95440.1 - 0.0002 21.5 0.4 0.0002 21.5 0.4 2.0 2 0 0 2 2 2 1 Histone acetyltransferases subunit 3 FANCL_C PF11793.8 OQR95440.1 - 0.0094 16.1 1.0 0.0094 16.1 1.0 2.4 2 0 0 2 2 2 1 FANCL C-terminal domain CHAD PF05235.14 OQR95440.1 - 0.059 13.3 0.2 0.11 12.5 0.2 1.3 1 0 0 1 1 1 0 CHAD domain PHD PF00628.29 OQR95440.1 - 0.11 12.5 12.2 0.06 13.3 3.9 2.5 2 0 0 2 2 2 0 PHD-finger C1_2 PF03107.16 OQR95440.1 - 3.4 8.0 7.0 1.4 9.3 1.1 2.5 2 0 0 2 2 2 0 C1 domain Zf_RING PF16744.5 OQR95440.1 - 3.9 7.7 8.4 0.37 10.9 2.1 2.3 2 0 0 2 2 2 0 KIAA1045 RING finger zf-RING_2 PF13639.6 OQR95440.1 - 9.3 6.7 11.7 6.1 7.3 3.1 2.5 2 0 0 2 2 2 0 Ring finger domain PNRC PF15365.6 OQR95441.1 - 5.9e-08 32.3 5.7 5.9e-08 32.3 5.7 2.6 2 1 0 2 2 2 1 Proline-rich nuclear receptor coactivator motif Ricin_B_lectin PF00652.22 OQR95442.1 - 1.8e-19 70.3 11.9 2.8e-11 43.8 5.0 3.1 2 1 1 3 3 3 3 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.6 OQR95442.1 - 2.2e-07 31.5 9.6 0.049 14.4 0.3 3.8 2 2 2 4 4 4 3 Ricin-type beta-trefoil lectin domain-like CDtoxinA PF03498.14 OQR95442.1 - 0.05 13.2 5.1 4.5 6.9 0.8 3.3 2 1 1 3 3 3 0 Cytolethal distending toxin A/C domain YchF-GTPase_C PF06071.13 OQR95443.1 - 1.9e-38 130.5 0.3 3.9e-38 129.5 0.3 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.23 OQR95443.1 - 7.7e-21 74.3 0.0 1.7e-20 73.2 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 OQR95443.1 - 3.9e-07 29.7 0.0 6.6e-07 29.0 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B MeaB PF03308.16 OQR95443.1 - 0.0074 15.3 0.0 0.015 14.3 0.0 1.4 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB Metallophos PF00149.28 OQR95445.1 - 6.4e-16 59.5 1.6 1.1e-15 58.7 1.6 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Pur_ac_phosph_N PF16656.5 OQR95445.1 - 6.6e-16 58.7 7.2 1.7e-15 57.4 7.2 1.7 1 0 0 1 1 1 1 Purple acid Phosphatase, N-terminal domain Metallophos_C PF14008.6 OQR95445.1 - 1.5e-12 48.1 0.1 4.4e-12 46.7 0.1 1.9 1 0 0 1 1 1 1 Iron/zinc purple acid phosphatase-like protein C PhoD_N PF16655.5 OQR95445.1 - 0.002 18.6 1.5 0.0037 17.8 0.5 2.0 2 0 0 2 2 2 1 PhoD-like phosphatase, N-terminal domain DUF2369 PF10179.9 OQR95445.1 - 0.0072 16.7 0.5 0.018 15.4 0.5 1.7 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2369) DUF1796 PF08795.10 OQR95445.1 - 0.013 15.5 0.8 0.5 10.3 0.4 2.4 2 0 0 2 2 2 0 Putative papain-like cysteine peptidase (DUF1796) Metallophos_2 PF12850.7 OQR95445.1 - 0.027 14.7 0.1 0.98 9.6 0.0 2.2 2 0 0 2 2 2 0 Calcineurin-like phosphoesterase superfamily domain Diphthamide_syn PF01866.17 OQR95446.1 - 5.7e-117 390.5 0.0 7.1e-117 390.2 0.0 1.1 1 0 0 1 1 1 1 Putative diphthamide synthesis protein DUF5331 PF17265.2 OQR95446.1 - 0.14 11.9 0.0 0.36 10.6 0.0 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5331) DUF3813 PF12758.7 OQR95447.1 - 0.01 16.1 0.0 0.023 15.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3813) TSSC4 PF15264.6 OQR95448.1 - 0.075 13.3 0.4 0.1 12.9 0.4 1.2 1 0 0 1 1 1 0 Tumour suppressing sub-chromosomal transferable candidate 4 Sod_Fe_C PF02777.18 OQR95450.1 - 3e-40 136.5 0.5 1.4e-39 134.4 0.0 2.2 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 OQR95450.1 - 4.2e-27 94.4 3.2 1e-26 93.2 3.2 1.7 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain Pyr_redox_2 PF07992.14 OQR95450.1 - 1.1e-13 51.1 0.0 1.1e-12 47.8 0.0 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OQR95450.1 - 0.0009 19.4 0.0 0.0023 18.1 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 OQR95450.1 - 0.0013 18.0 0.0 0.99 8.6 0.0 3.2 3 0 0 3 3 3 1 Thi4 family NAD_binding_7 PF13241.6 OQR95450.1 - 0.0075 16.7 0.1 2.5 8.6 0.0 2.7 2 0 0 2 2 2 1 Putative NAD(P)-binding NAD_binding_9 PF13454.6 OQR95450.1 - 0.019 14.9 0.0 0.07 13.1 0.0 2.0 2 0 0 2 2 2 0 FAD-NAD(P)-binding Pyr_redox PF00070.27 OQR95450.1 - 0.026 15.1 0.0 3.1 8.4 0.0 2.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pkinase PF00069.25 OQR95451.1 - 3.4e-68 229.9 0.0 4.2e-68 229.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQR95451.1 - 2.1e-31 109.1 0.0 3e-31 108.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 OQR95451.1 - 0.0074 15.7 0.2 0.017 14.5 0.2 1.5 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 OQR95451.1 - 0.03 14.0 0.4 0.71 9.4 0.1 2.3 1 1 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Haspin_kinase PF12330.8 OQR95451.1 - 0.038 12.9 0.2 0.062 12.2 0.2 1.4 1 1 0 1 1 1 0 Haspin like kinase domain Spa1_C PF18218.1 OQR95451.1 - 0.046 14.1 0.0 11 6.5 0.0 2.7 2 1 0 2 2 2 0 Lantibiotic immunity protein Spa1 C-terminal domain Kinase-like PF14531.6 OQR95451.1 - 0.067 12.5 0.1 0.27 10.5 0.0 1.9 1 1 1 2 2 2 0 Kinase-like Pox_VLTF3 PF04947.14 OQR95451.1 - 0.12 12.1 0.7 0.22 11.2 0.7 1.4 1 0 0 1 1 1 0 Poxvirus Late Transcription Factor VLTF3 like XPG_I PF00867.18 OQR95452.1 - 3.2e-26 91.5 1.2 5.5e-26 90.8 0.3 1.9 2 0 0 2 2 2 1 XPG I-region XPG_N PF00752.17 OQR95452.1 - 8.9e-21 74.3 0.0 2.1e-20 73.1 0.0 1.7 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I_2 PF12813.7 OQR95452.1 - 5.4e-07 29.3 0.1 9e-07 28.6 0.1 1.3 1 0 0 1 1 1 1 XPG domain containing 5_3_exonuc PF01367.20 OQR95452.1 - 0.0085 16.7 0.0 0.019 15.6 0.0 1.5 1 0 0 1 1 1 1 5'-3' exonuclease, C-terminal SAM fold AAA PF00004.29 OQR95453.1 - 5.9e-39 133.5 0.0 2e-38 131.8 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) TMEM138 PF14935.6 OQR95453.1 - 2.6e-18 66.8 7.4 3.9e-18 66.2 7.4 1.3 1 0 0 1 1 1 1 Transmembrane protein 138 AAA_lid_3 PF17862.1 OQR95453.1 - 1.7e-08 34.2 0.0 5.4e-08 32.5 0.0 1.9 1 0 0 1 1 1 1 AAA+ lid domain AAA_2 PF07724.14 OQR95453.1 - 9.3e-06 25.9 0.0 1.6e-05 25.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 OQR95453.1 - 1.5e-05 24.8 0.0 3e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 OQR95453.1 - 0.00033 20.6 0.0 0.0013 18.8 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Vps4_C PF09336.10 OQR95453.1 - 0.00035 20.5 0.0 0.0011 18.9 0.0 1.9 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain Mg_chelatase PF01078.21 OQR95453.1 - 0.0034 16.8 0.0 0.0057 16.1 0.0 1.3 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 OQR95453.1 - 0.0046 17.1 0.0 0.015 15.5 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 OQR95453.1 - 0.0056 17.0 0.1 0.22 11.8 0.0 2.5 1 1 1 2 2 2 1 AAA domain TIP49 PF06068.13 OQR95453.1 - 0.0096 15.2 0.0 0.017 14.3 0.0 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_16 PF13191.6 OQR95453.1 - 0.012 15.9 0.0 0.065 13.6 0.0 2.2 2 1 0 2 2 2 0 AAA ATPase domain IstB_IS21 PF01695.17 OQR95453.1 - 0.015 15.1 0.0 0.029 14.1 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_14 PF13173.6 OQR95453.1 - 0.023 14.7 0.0 0.044 13.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain Parvo_NS1 PF01057.17 OQR95453.1 - 0.026 13.6 0.0 0.096 11.8 0.0 1.8 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 DUF815 PF05673.13 OQR95453.1 - 0.027 13.6 0.0 0.048 12.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_7 PF12775.7 OQR95453.1 - 0.05 13.1 0.0 0.09 12.3 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region PhoH PF02562.16 OQR95453.1 - 0.11 11.9 0.0 0.21 11.0 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein RNA_helicase PF00910.22 OQR95453.1 - 0.15 12.4 0.0 0.29 11.5 0.0 1.6 1 0 0 1 1 1 0 RNA helicase TsaE PF02367.17 OQR95453.1 - 0.17 11.9 0.0 0.32 11.0 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE p450 PF00067.22 OQR95453.1 - 0.21 10.3 0.0 0.34 9.6 0.0 1.2 1 0 0 1 1 1 0 Cytochrome P450 Ank_2 PF12796.7 OQR95454.1 - 1.2e-30 105.9 7.2 5.7e-14 52.5 0.2 4.1 1 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQR95454.1 - 1.5e-26 92.4 5.4 1.4e-10 41.4 0.1 5.3 3 2 1 4 4 4 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 OQR95454.1 - 9e-23 80.0 7.0 6.4e-07 29.5 0.0 5.5 3 2 3 6 6 6 4 Ankyrin repeats (many copies) Ank PF00023.30 OQR95454.1 - 9.4e-22 76.4 14.6 1.4e-07 31.6 0.0 6.1 6 1 0 6 6 6 3 Ankyrin repeat Ank_3 PF13606.6 OQR95454.1 - 2.3e-20 70.5 8.3 7.5e-05 22.8 0.0 6.4 6 1 1 7 7 7 4 Ankyrin repeat PRKCSH_1 PF13015.6 OQR95455.1 - 4.6e-32 110.8 0.1 8.8e-32 109.9 0.1 1.4 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein PRKCSH-like PF12999.7 OQR95455.1 - 1e-25 90.5 9.0 1e-25 90.5 9.0 1.5 1 1 0 1 1 1 1 Glucosidase II beta subunit-like NPV_P10 PF05531.12 OQR95455.1 - 3.7 8.1 5.4 3.4 8.2 0.0 3.0 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Pkinase PF00069.25 OQR95456.1 - 6.2e-63 212.6 0.0 7.7e-63 212.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQR95456.1 - 1.3e-30 106.5 0.0 1.7e-30 106.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OQR95456.1 - 1.6e-06 27.7 0.0 1.3e-05 24.7 0.0 2.0 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 OQR95456.1 - 0.00019 20.9 0.1 0.00029 20.3 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 OQR95456.1 - 0.00023 20.0 0.0 0.00035 19.5 0.0 1.3 1 1 0 1 1 1 1 Fungal protein kinase RIO1 PF01163.22 OQR95456.1 - 0.0036 16.9 0.4 0.15 11.7 0.0 2.0 1 1 1 2 2 2 1 RIO1 family APH PF01636.23 OQR95456.1 - 0.07 13.0 0.0 8.2 6.3 0.0 2.3 1 1 1 2 2 2 0 Phosphotransferase enzyme family Aminotran_1_2 PF00155.21 OQR95457.1 - 8.9e-44 150.1 0.0 1.1e-43 149.9 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Lipase_GDSL_2 PF13472.6 OQR95457.1 - 0.18 12.2 0.0 0.65 10.4 0.0 1.9 2 0 0 2 2 2 0 GDSL-like Lipase/Acylhydrolase family EI24 PF07264.11 OQR95458.1 - 0.26 11.5 11.3 0.39 11.0 11.3 1.3 1 0 0 1 1 1 0 Etoposide-induced protein 2.4 (EI24) RSN1_7TM PF02714.15 OQR95459.1 - 3.4e-29 102.0 26.2 3.4e-29 102.0 26.2 2.7 2 1 0 2 2 2 1 Calcium-dependent channel, 7TM region, putative phosphate PHM7_cyt PF14703.6 OQR95459.1 - 4.2e-12 46.7 0.1 6.7e-12 46.0 0.1 1.3 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter RSN1_TM PF13967.6 OQR95459.1 - 6.2e-11 42.3 5.8 6.2e-11 42.3 5.8 3.3 4 1 0 4 4 4 1 Late exocytosis, associated with Golgi transport JAKMIP_CC3 PF16034.5 OQR95460.1 - 0.022 14.7 1.6 0.047 13.6 1.6 1.4 1 0 0 1 1 1 0 JAKMIP CC3 domain Vps5 PF09325.10 OQR95460.1 - 0.026 14.1 1.2 0.042 13.4 1.2 1.3 1 0 0 1 1 1 0 Vps5 C terminal like DivIC PF04977.15 OQR95460.1 - 0.079 12.7 0.4 0.16 11.8 0.4 1.4 1 0 0 1 1 1 0 Septum formation initiator T3SS_needle_E PF08988.10 OQR95460.1 - 0.08 13.1 1.5 0.25 11.5 1.5 1.8 1 0 0 1 1 1 0 Type III secretion system, cytoplasmic E component of needle Sec8_exocyst PF04048.14 OQR95460.1 - 0.094 12.6 1.6 0.24 11.3 1.6 1.6 1 0 0 1 1 1 0 Sec8 exocyst complex component specific domain CC2-LZ PF16516.5 OQR95460.1 - 0.11 12.8 2.7 0.24 11.8 2.7 1.5 1 0 0 1 1 1 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator zf-CCCH PF00642.24 OQR95460.1 - 0.63 10.0 3.4 8 6.5 3.4 2.4 1 1 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) XhlA PF10779.9 OQR95460.1 - 0.77 10.0 2.9 1.5 9.0 2.9 1.5 1 0 0 1 1 1 0 Haemolysin XhlA ZZ PF00569.17 OQR95461.1 - 2e-29 101.2 8.6 2.4e-12 46.5 0.1 3.4 3 0 0 3 3 3 3 Zinc finger, ZZ type N_BRCA1_IG PF16158.5 OQR95461.1 - 6.8e-29 100.6 0.0 1.7e-28 99.3 0.0 1.8 1 0 0 1 1 1 1 Ig-like domain from next to BRCA1 gene UBA PF00627.31 OQR95461.1 - 0.00017 21.4 0.3 0.00017 21.4 0.3 1.9 2 0 0 2 2 2 1 UBA/TS-N domain PB1 PF00564.24 OQR95461.1 - 0.00017 21.4 0.0 0.00053 19.9 0.0 1.8 1 0 0 1 1 1 1 PB1 domain DUF3795 PF12675.7 OQR95461.1 - 9.8 6.7 9.8 58 4.2 1.6 3.5 1 1 2 3 3 3 0 Protein of unknown function (DUF3795) Ribosomal_L2_C PF03947.18 OQR95462.1 - 8.8e-48 161.7 3.1 1.1e-47 161.4 2.5 1.4 2 0 0 2 2 2 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 OQR95462.1 - 1.5e-16 60.1 0.2 4.4e-16 58.6 0.2 1.8 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain Myosin_N PF02736.19 OQR95462.1 - 0.044 13.6 1.1 2.6 7.9 0.2 2.4 2 0 0 2 2 2 0 Myosin N-terminal SH3-like domain MinC_C PF03775.16 OQR95463.1 - 2.3e-29 101.4 0.1 3.9e-29 100.6 0.1 1.4 1 0 0 1 1 1 1 Septum formation inhibitor MinC, C-terminal domain FapA PF03961.13 OQR95463.1 - 0.00086 18.0 0.7 0.00086 18.0 0.7 1.6 1 1 1 2 2 2 1 Flagellar Assembly Protein A DUF4772 PF15997.5 OQR95463.1 - 0.12 13.0 0.0 0.23 12.1 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4772) Ion_trans PF00520.31 OQR95466.1 - 3.5e-07 29.7 3.4 4.3e-07 29.4 3.4 1.0 1 0 0 1 1 1 1 Ion transport protein DUF4168 PF13767.6 OQR95467.1 - 0.03 15.5 0.1 0.044 15.0 0.1 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4168) LRR_6 PF13516.6 OQR95468.1 - 9.2e-11 40.9 11.4 0.00053 19.8 0.0 6.4 6 0 0 6 6 6 3 Leucine Rich repeat LRR_8 PF13855.6 OQR95468.1 - 1.8e-07 30.8 11.3 4.2e-05 23.2 0.3 4.1 2 2 0 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 OQR95468.1 - 1.9e-07 31.3 2.1 0.0009 19.6 0.1 5.9 3 3 3 6 6 6 4 Leucine Rich repeats (2 copies) FNIP PF05725.12 OQR95468.1 - 0.28 11.4 3.2 18 5.6 0.0 4.4 5 1 0 5 5 5 0 FNIP Repeat LRR_1 PF00560.33 OQR95468.1 - 0.33 11.7 8.1 20 6.3 0.0 6.0 6 0 0 6 6 6 0 Leucine Rich Repeat Ank_2 PF12796.7 OQR95469.1 - 7.4e-09 36.1 0.1 2.6e-06 27.9 0.0 2.8 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OQR95469.1 - 1.4e-08 34.8 0.0 1.2e-06 28.7 0.0 2.9 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 OQR95469.1 - 1.4e-06 28.7 0.2 0.027 15.1 0.0 3.7 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQR95469.1 - 0.012 16.0 0.0 13 6.8 0.0 3.8 2 0 0 2 2 2 0 Ankyrin repeat PLDc_N PF13396.6 OQR95469.1 - 0.028 14.3 0.6 0.028 14.3 0.6 4.3 5 0 0 5 5 4 0 Phospholipase_D-nuclease N-terminal KELK PF15796.5 OQR95469.1 - 0.068 13.6 2.8 0.15 12.6 2.8 1.5 1 0 0 1 1 1 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF4407 PF14362.6 OQR95469.1 - 0.075 12.4 1.8 0.12 11.7 0.3 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Ank PF00023.30 OQR95469.1 - 0.09 13.3 0.0 20 5.9 0.0 3.9 4 0 0 4 4 4 0 Ankyrin repeat bZIP_1 PF00170.21 OQR95469.1 - 0.49 10.5 4.0 1.1 9.4 4.0 1.6 1 0 0 1 1 1 0 bZIP transcription factor Elf1 PF05129.13 OQR95469.1 - 3.4 7.8 5.0 2.6 8.1 1.3 2.2 2 0 0 2 2 2 0 Transcription elongation factor Elf1 like COMP PF11598.8 OQR95469.1 - 5.3 7.6 7.1 1.5 9.3 3.1 2.3 1 1 1 2 2 2 0 Cartilage oligomeric matrix protein Takusan PF04822.13 OQR95471.1 - 0.029 14.2 7.8 0.031 14.1 0.4 3.3 3 1 1 4 4 4 0 Takusan G_path_suppress PF15991.5 OQR95471.1 - 0.14 12.3 14.1 0.28 11.3 14.1 1.5 1 0 0 1 1 1 0 G-protein pathway suppressor Erf4 PF10256.9 OQR95471.1 - 0.37 10.9 2.5 4 7.6 0.2 3.0 2 0 0 2 2 2 0 Golgin subfamily A member 7/ERF4 family FliJ PF02050.16 OQR95471.1 - 1.7 8.9 26.0 0.051 13.8 9.3 2.3 1 1 1 2 2 2 0 Flagellar FliJ protein CN_hydrolase PF00795.22 OQR95472.1 - 6.3e-11 42.1 0.0 3.1e-07 30.0 0.0 2.2 2 0 0 2 2 2 2 Carbon-nitrogen hydrolase Dpy-30 PF05186.13 OQR95473.1 - 0.0002 21.0 0.0 0.55 10.0 0.0 2.5 2 0 0 2 2 2 2 Dpy-30 motif IQ PF00612.27 OQR95473.1 - 0.004 16.8 6.7 0.016 15.0 0.1 3.9 3 0 0 3 3 3 2 IQ calmodulin-binding motif EMP24_GP25L PF01105.24 OQR95474.1 - 2.3e-13 50.5 0.4 1.3e-06 28.5 0.0 2.2 2 0 0 2 2 2 2 emp24/gp25L/p24 family/GOLD BT1 PF03092.16 OQR95475.1 - 4.8e-12 44.9 6.2 1.4e-09 36.7 1.4 3.3 3 0 0 3 3 3 3 BT1 family ABC_tran PF00005.27 OQR95476.1 - 3.6e-48 163.5 0.0 2.5e-24 86.3 0.0 3.3 2 2 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 OQR95476.1 - 2.6e-15 57.0 0.0 1.6e-05 24.9 0.0 3.9 3 1 0 3 3 3 3 AAA domain, putative AbiEii toxin, Type IV TA system Acyltransferase PF01553.21 OQR95476.1 - 1.1e-13 50.9 0.0 6.8e-13 48.4 0.0 2.3 2 0 0 2 2 2 1 Acyltransferase SMC_N PF02463.19 OQR95476.1 - 1.4e-12 47.6 2.9 0.01 15.3 0.0 4.8 4 1 1 5 5 5 4 RecF/RecN/SMC N terminal domain AAA_28 PF13521.6 OQR95476.1 - 1.9e-07 31.5 0.0 0.029 14.6 0.0 3.1 3 0 0 3 3 3 2 AAA domain AAA_29 PF13555.6 OQR95476.1 - 2.8e-07 30.2 0.4 0.075 12.8 0.1 3.4 3 0 0 3 3 3 2 P-loop containing region of AAA domain Chromo PF00385.24 OQR95476.1 - 1.9e-06 27.7 2.3 4.4e-06 26.5 2.3 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain AAA_22 PF13401.6 OQR95476.1 - 3e-06 27.5 0.1 0.18 12.0 0.0 3.8 4 0 0 4 4 3 2 AAA domain AAA PF00004.29 OQR95476.1 - 1.4e-05 25.5 0.0 0.033 14.6 0.0 3.5 4 0 0 4 4 2 1 ATPase family associated with various cellular activities (AAA) MMR_HSR1 PF01926.23 OQR95476.1 - 2.4e-05 24.4 0.0 0.12 12.5 0.0 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 OQR95476.1 - 3.1e-05 24.0 0.0 0.12 12.3 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_15 PF13175.6 OQR95476.1 - 3.6e-05 23.6 2.3 0.16 11.6 0.0 3.7 3 0 0 3 3 3 2 AAA ATPase domain RNA_helicase PF00910.22 OQR95476.1 - 3.6e-05 24.1 0.0 0.095 13.1 0.0 3.1 3 0 0 3 3 2 1 RNA helicase AAA_23 PF13476.6 OQR95476.1 - 9.2e-05 23.0 17.4 0.0028 18.2 0.0 4.7 4 1 0 4 4 3 1 AAA domain AAA_33 PF13671.6 OQR95476.1 - 0.00011 22.4 0.0 1 9.6 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.6 OQR95476.1 - 0.00011 22.7 0.0 0.37 11.4 0.0 2.8 2 0 0 2 2 2 2 AAA domain 4HB PF17947.1 OQR95476.1 - 0.00014 21.9 0.1 0.0021 18.1 0.0 2.6 2 0 0 2 2 2 1 Four helical bundle domain Cnd1 PF12717.7 OQR95476.1 - 0.00055 20.0 1.0 1.2 9.2 0.0 2.5 1 1 1 2 2 2 2 non-SMC mitotic condensation complex subunit 1 Rad17 PF03215.15 OQR95476.1 - 0.0008 19.4 0.0 0.74 9.7 0.0 2.6 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_16 PF13191.6 OQR95476.1 - 0.0013 19.1 0.0 2.6 8.4 0.0 2.9 2 0 0 2 2 2 1 AAA ATPase domain ATPase_2 PF01637.18 OQR95476.1 - 0.0018 18.2 0.0 0.15 11.9 0.0 3.2 3 0 0 3 3 2 1 ATPase domain predominantly from Archaea AAA_27 PF13514.6 OQR95476.1 - 0.0019 17.8 0.1 0.83 9.2 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 OQR95476.1 - 0.0022 17.7 0.2 2.3 7.9 0.0 3.7 3 0 0 3 3 3 1 AAA domain AAA_7 PF12775.7 OQR95476.1 - 0.0051 16.4 0.0 3.7 7.0 0.0 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region Adaptin_N PF01602.20 OQR95476.1 - 0.0055 15.3 1.2 0.009 14.6 1.2 1.3 1 0 0 1 1 1 1 Adaptin N terminal region NACHT PF05729.12 OQR95476.1 - 0.0056 16.6 0.0 0.51 10.2 0.0 2.7 2 0 0 2 2 2 1 NACHT domain AAA_24 PF13479.6 OQR95476.1 - 0.0065 16.2 0.1 0.72 9.5 0.1 2.7 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.6 OQR95476.1 - 0.0082 16.2 0.0 0.84 9.7 0.0 2.8 2 0 0 2 2 2 1 AAA domain SbcCD_C PF13558.6 OQR95476.1 - 0.01 16.1 0.4 0.45 10.8 0.0 3.4 3 1 0 3 3 3 0 Putative exonuclease SbcCD, C subunit CLASP_N PF12348.8 OQR95476.1 - 0.011 15.4 0.5 0.061 12.9 0.1 2.3 2 0 0 2 2 2 0 CLASP N terminal G-alpha PF00503.20 OQR95476.1 - 0.017 14.3 0.0 6.2 5.9 0.0 2.5 2 0 0 2 2 2 0 G-protein alpha subunit MeaB PF03308.16 OQR95476.1 - 0.021 13.8 0.3 5 6.0 0.1 2.4 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Dynamin_N PF00350.23 OQR95476.1 - 0.042 13.9 0.0 0.39 10.8 0.0 2.6 2 0 0 2 2 2 0 Dynamin family NB-ARC PF00931.22 OQR95476.1 - 0.048 12.9 0.0 1.2 8.2 0.0 2.6 2 0 0 2 2 2 0 NB-ARC domain ATP-synt_ab PF00006.25 OQR95476.1 - 0.074 12.7 0.0 3.5 7.2 0.0 2.4 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain DUF815 PF05673.13 OQR95476.1 - 0.079 12.1 0.0 12 4.9 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF815) Cytidylate_kin PF02224.18 OQR95476.1 - 0.11 12.3 0.0 13 5.4 0.0 2.7 2 0 0 2 2 2 0 Cytidylate kinase PduV-EutP PF10662.9 OQR95476.1 - 0.14 11.9 0.1 29 4.4 0.1 2.8 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation HEAT_2 PF13646.6 OQR95476.1 - 0.14 12.6 5.2 0.13 12.7 2.2 2.6 2 1 1 3 3 2 0 HEAT repeats CcmD PF04995.14 OQR95476.1 - 0.29 11.2 3.6 0.18 11.9 0.4 2.1 2 0 0 2 2 2 0 Heme exporter protein D (CcmD) Mg_chelatase PF01078.21 OQR95476.1 - 0.42 9.9 2.4 21 4.4 0.0 3.1 3 0 0 3 3 2 0 Magnesium chelatase, subunit ChlI HEAT PF02985.22 OQR95476.1 - 0.69 10.3 4.4 36 5.0 0.3 4.6 5 0 0 5 5 4 0 HEAT repeat Pkinase PF00069.25 OQR95477.1 - 2.9e-66 223.5 0.0 5.2e-66 222.7 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQR95477.1 - 6e-35 120.8 0.0 1.4e-34 119.5 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.23 OQR95477.1 - 5.9e-06 26.4 0.0 0.00023 21.2 0.0 2.4 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 OQR95477.1 - 0.00058 19.3 0.0 0.14 11.5 0.0 2.4 2 0 0 2 2 2 2 Kinase-like Pkinase_fungal PF17667.1 OQR95477.1 - 0.0013 17.6 0.0 0.0021 16.9 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Choline_kinase PF01633.20 OQR95477.1 - 0.06 12.9 0.1 0.17 11.4 0.0 1.7 2 0 0 2 2 2 0 Choline/ethanolamine kinase CLASP_N PF12348.8 OQR95478.1 - 0.013 15.0 0.0 0.022 14.4 0.0 1.3 1 1 0 1 1 1 0 CLASP N terminal NUC173 PF08161.12 OQR95478.1 - 0.04 13.6 0.1 0.085 12.5 0.0 1.5 2 0 0 2 2 2 0 NUC173 domain zf-RING_2 PF13639.6 OQR95479.1 - 7.1e-10 39.1 10.1 1.5e-09 38.0 10.1 1.6 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 OQR95479.1 - 1.9e-08 34.5 6.5 3.4e-08 33.6 6.5 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_11 PF17123.5 OQR95479.1 - 2.6e-06 27.0 8.4 6.5e-06 25.8 8.4 1.7 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4 PF00097.25 OQR95479.1 - 4.7e-06 26.4 9.3 7.8e-06 25.7 9.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 OQR95479.1 - 6.4e-06 26.1 3.4 1.3e-05 25.1 3.4 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_2 PF13923.6 OQR95479.1 - 0.0028 17.4 11.4 0.0082 16.0 11.4 1.8 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OQR95479.1 - 0.0032 17.5 3.7 0.0032 17.5 3.7 2.3 2 1 1 3 3 3 1 RING-type zinc-finger zf-RING_5 PF14634.6 OQR95479.1 - 0.01 15.7 8.3 0.019 14.9 8.3 1.5 1 0 0 1 1 1 0 zinc-RING finger domain Prok-RING_4 PF14447.6 OQR95479.1 - 0.029 14.2 8.1 0.063 13.1 8.1 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 Zn_ribbon_17 PF17120.5 OQR95479.1 - 0.072 12.7 6.2 0.15 11.7 6.2 1.5 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type FANCL_C PF11793.8 OQR95479.1 - 0.59 10.4 10.6 1.6 9.0 9.1 2.3 2 1 0 2 2 2 0 FANCL C-terminal domain RINGv PF12906.7 OQR95479.1 - 1.1 9.4 9.0 2.3 8.4 9.0 1.6 1 0 0 1 1 1 0 RING-variant domain MMR_HSR1_Xtn PF16897.5 OQR95480.1 - 9.8e-42 141.3 0.8 2.1e-41 140.2 0.8 1.6 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain MMR_HSR1 PF01926.23 OQR95480.1 - 4e-20 72.0 0.0 8.7e-20 70.9 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase TGS PF02824.21 OQR95480.1 - 1.1e-18 67.0 0.0 2.1e-18 66.1 0.0 1.5 1 0 0 1 1 1 1 TGS domain FeoB_N PF02421.18 OQR95480.1 - 2.4e-10 40.2 0.1 1.2e-09 37.8 0.0 2.0 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.23 OQR95480.1 - 0.00033 20.7 1.1 0.087 12.9 0.0 2.8 2 1 1 3 3 3 2 Dynamin family MeaB PF03308.16 OQR95480.1 - 0.00041 19.4 0.2 0.0041 16.1 0.2 2.2 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB GTP_EFTU PF00009.27 OQR95480.1 - 0.028 13.9 0.9 0.76 9.3 0.9 3.3 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain AIG1 PF04548.16 OQR95480.1 - 0.13 11.6 0.0 0.18 11.1 0.0 1.3 1 0 0 1 1 1 0 AIG1 family Tetraspanin PF00335.20 OQR95481.1 - 0.15 11.7 0.2 0.15 11.7 0.2 1.5 2 0 0 2 2 2 0 Tetraspanin family FtsX PF02687.21 OQR95481.1 - 1.4 9.4 5.9 2.4 8.7 5.9 1.3 1 0 0 1 1 1 0 FtsX-like permease family ArgJ PF01960.18 OQR95483.1 - 1.8e-109 365.9 0.0 2.2e-109 365.6 0.0 1.0 1 0 0 1 1 1 1 ArgJ family DUF2249 PF10006.9 OQR95483.1 - 0.17 11.8 0.1 0.39 10.6 0.1 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2249) MORN PF02493.20 OQR95485.1 - 1.6e-14 52.8 38.6 0.025 14.4 0.4 9.7 10 0 0 10 10 10 8 MORN repeat tRNA_int_endo PF01974.17 OQR95486.1 - 5.4e-20 71.3 0.0 1.1e-19 70.2 0.0 1.5 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain Phage_CI_C PF16452.5 OQR95486.1 - 0.15 12.3 0.0 0.29 11.4 0.0 1.5 1 0 0 1 1 1 0 Bacteriophage CI repressor C-terminal domain tRNA_int_endo_N PF02778.14 OQR95486.1 - 0.16 11.6 0.0 0.45 10.2 0.0 1.7 2 0 0 2 2 2 0 tRNA intron endonuclease, N-terminal domain C2 PF00168.30 OQR95487.1 - 1.1e-40 138.1 0.0 8.4e-20 71.0 0.0 2.5 2 0 0 2 2 2 2 C2 domain 5_3_exonuc_N PF02739.16 OQR95487.1 - 0.00032 20.6 0.5 0.26 11.2 0.1 2.9 2 1 0 2 2 2 2 5'-3' exonuclease, N-terminal resolvase-like domain NT-C2 PF10358.9 OQR95487.1 - 0.0014 18.3 0.0 1.7 8.4 0.0 2.5 2 0 0 2 2 2 2 N-terminal C2 in EEIG1 and EHBP1 proteins DUF1192 PF06698.11 OQR95487.1 - 0.4 10.8 8.1 2.3 8.3 0.3 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1192) DUF4293 PF14126.6 OQR95488.1 - 1.9 8.7 12.1 0.48 10.7 7.2 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4293) LRR19-TM PF15176.6 OQR95489.1 - 0.045 13.7 0.9 0.34 10.9 0.9 2.5 1 0 0 1 1 1 0 Leucine-rich repeat family 19 TM domain Phage_tail_APC PF16778.5 OQR95489.1 - 1.7 8.6 7.6 3.2 7.7 0.1 4.6 4 0 0 4 4 4 0 Phage tail assembly chaperone protein Pec_lyase_N PF04431.13 OQR95489.1 - 4.7 7.5 9.6 0.51 10.6 0.2 3.9 4 0 0 4 4 4 0 Pectate lyase, N terminus Pescadillo_N PF06732.11 OQR95490.1 - 6.4e-115 383.4 1.7 1.2e-114 382.5 1.7 1.4 1 0 0 1 1 1 1 Pescadillo N-terminus BRCT_2 PF16589.5 OQR95490.1 - 2.6e-11 43.8 0.0 6.8e-11 42.4 0.0 1.8 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 OQR95490.1 - 0.057 13.8 0.0 0.32 11.4 0.0 2.3 1 1 0 1 1 1 0 BRCA1 C Terminus (BRCT) domain LIG3_BRCT PF16759.5 OQR95490.1 - 0.1 12.9 0.0 0.36 11.2 0.0 2.0 1 1 0 1 1 1 0 DNA ligase 3 BRCT domain SUA5 PF03481.13 OQR95490.1 - 0.31 11.6 3.4 0.37 11.4 0.1 2.4 2 0 0 2 2 2 0 Putative GTP-binding controlling metal-binding PRP1_N PF06424.12 OQR95491.1 - 1.5e-52 177.9 0.1 2.7e-52 177.1 0.1 1.4 1 0 0 1 1 1 1 PRP1 splicing factor, N-terminal TPR_14 PF13428.6 OQR95491.1 - 1.3e-27 94.1 24.4 0.00045 20.8 0.2 12.8 6 4 8 14 14 14 9 Tetratricopeptide repeat TPR_19 PF14559.6 OQR95491.1 - 3.1e-19 69.2 1.6 2.7e-08 34.2 0.2 8.0 6 3 2 8 8 8 3 Tetratricopeptide repeat TPR_2 PF07719.17 OQR95491.1 - 1.1e-06 28.3 6.9 0.52 10.5 0.1 6.9 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_16 PF13432.6 OQR95491.1 - 5.7e-06 26.9 8.1 0.1 13.2 2.8 6.0 6 0 0 6 6 6 1 Tetratricopeptide repeat Wzy_C_2 PF11846.8 OQR95491.1 - 0.00094 19.1 3.7 1.9 8.4 0.1 3.6 3 0 0 3 3 3 2 Virulence factor membrane-bound polymerase, C-terminal TPR_8 PF13181.6 OQR95491.1 - 0.0013 18.8 0.0 28 5.2 0.2 5.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_17 PF13431.6 OQR95491.1 - 0.0016 18.7 1.0 56 4.4 0.0 7.0 9 0 0 9 9 9 0 Tetratricopeptide repeat UPF0184 PF03670.13 OQR95491.1 - 0.24 11.8 1.0 0.81 10.1 1.0 1.8 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0184) fn2 PF00040.19 OQR95491.1 - 1.1 9.6 2.4 1.3 9.4 0.1 2.2 2 0 0 2 2 2 0 Fibronectin type II domain tRNA-synt_2 PF00152.20 OQR95495.1 - 2.3e-81 273.3 0.4 2.8e-81 273.0 0.4 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA-synt_2d PF01409.20 OQR95495.1 - 2.6e-06 27.1 0.0 0.0031 17.1 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) tRNA_anti-codon PF01336.25 OQR95495.1 - 4.6e-05 23.3 0.0 0.00015 21.7 0.0 1.9 2 0 0 2 2 2 1 OB-fold nucleic acid binding domain DUF150_C PF17384.2 OQR95495.1 - 0.064 13.4 0.0 0.34 11.1 0.0 2.2 2 0 0 2 2 2 0 RimP C-terminal SH3 domain MatE PF01554.18 OQR95496.1 - 1.6e-37 128.6 34.9 1.4e-22 80.0 13.0 2.3 2 0 0 2 2 2 2 MatE Trypsin PF00089.26 OQR95497.1 - 4.5e-29 101.8 0.1 5.2e-29 101.6 0.1 1.0 1 0 0 1 1 1 1 Trypsin DUF316 PF03761.15 OQR95497.1 - 0.033 13.8 0.0 0.19 11.3 0.0 2.0 2 0 0 2 2 2 0 Chymotrypsin family Peptidase-S1 Voltage_CLC PF00654.20 OQR95499.1 - 1.8e-87 293.9 24.9 2.2e-86 290.3 23.6 2.0 1 1 1 2 2 2 2 Voltage gated chloride channel CBS PF00571.28 OQR95499.1 - 1.1e-10 41.8 0.0 6.5e-06 26.5 0.0 2.9 2 1 0 2 2 2 2 CBS domain WW PF00397.26 OQR95501.1 - 9e-21 73.7 13.4 1.4e-10 41.1 2.5 2.3 2 0 0 2 2 2 2 WW domain MbtH PF03621.13 OQR95501.1 - 0.1 12.1 0.3 8.2 6.0 0.0 2.6 3 0 0 3 3 3 0 MbtH-like protein Hydrolase_2 PF07486.12 OQR95501.1 - 0.17 12.7 2.3 1.5 9.7 0.9 2.5 2 1 0 2 2 2 0 Cell Wall Hydrolase Glyco_hyd_101C PF17451.2 OQR95501.1 - 0.44 10.9 8.1 3.5 7.9 0.7 2.5 1 1 1 2 2 2 0 Glycosyl hydrolase 101 beta sandwich domain MatE PF01554.18 OQR95502.1 - 1.7e-72 242.3 81.5 2.1e-20 73.0 16.7 4.6 5 0 0 5 5 5 4 MatE NYD-SP28 PF14772.6 OQR95502.1 - 0.12 12.4 0.0 17 5.5 0.0 2.2 2 0 0 2 2 2 0 Sperm tail Trypsin PF00089.26 OQR95503.1 - 2.2e-15 57.1 0.1 2.5e-15 56.9 0.1 1.0 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 OQR95503.1 - 5.5e-05 24.1 0.0 6.6e-05 23.9 0.0 1.1 1 0 0 1 1 1 1 Trypsin-like peptidase domain Peptidase_C2 PF00648.21 OQR95504.1 - 1.6e-54 185.0 0.5 2.4e-54 184.4 0.5 1.3 1 0 0 1 1 1 1 Calpain family cysteine protease Calpain_III PF01067.22 OQR95504.1 - 3e-29 102.1 0.1 1.8e-11 44.4 0.0 4.2 4 0 0 4 4 4 3 Calpain large subunit, domain III MAM PF00629.23 OQR95504.1 - 0.059 13.3 0.5 0.18 11.7 0.5 1.8 1 0 0 1 1 1 0 MAM domain, meprin/A5/mu PX PF00787.24 OQR95507.1 - 8.4e-24 83.7 0.3 1.4e-23 83.0 0.3 1.4 1 0 0 1 1 1 1 PX domain Vps5 PF09325.10 OQR95507.1 - 0.00046 19.8 0.7 0.00077 19.1 0.7 1.3 1 0 0 1 1 1 1 Vps5 C terminal like BAR_3_WASP_bdg PF10456.9 OQR95507.1 - 0.043 13.3 0.1 0.1 12.1 0.1 1.5 1 1 0 1 1 1 0 WASP-binding domain of Sorting nexin protein EF-hand_1 PF00036.32 OQR95507.1 - 0.15 11.7 0.1 0.31 10.7 0.1 1.5 1 0 0 1 1 1 0 EF hand DUF3144 PF11342.8 OQR95507.1 - 5 7.5 6.5 15 6.0 2.1 3.4 4 0 0 4 4 4 0 Protein of unknown function (DUF3144) Pyridoxal_deC PF00282.19 OQR95508.1 - 3.1e-19 69.0 0.0 6.4e-19 67.9 0.0 1.5 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.19 OQR95508.1 - 1.7e-09 37.1 0.1 6.5e-09 35.2 0.1 1.8 1 1 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 OQR95508.1 - 0.00011 21.7 0.6 0.00016 21.1 0.6 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.20 OQR95508.1 - 0.015 13.9 0.0 0.025 13.1 0.0 1.3 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme ACBP PF00887.19 OQR95509.1 - 2.2e-31 107.9 1.4 2.4e-31 107.8 1.4 1.0 1 0 0 1 1 1 1 Acyl CoA binding protein PYST-C1 PF09690.10 OQR95510.1 - 6.5 6.6 6.5 1.5e+02 2.3 6.2 2.3 2 0 0 2 2 2 0 Plasmodium yoelii subtelomeric region (PYST-C1) LsmAD PF06741.13 OQR95511.1 - 3.2e-20 72.4 0.2 9.2e-20 71.0 0.2 1.8 1 0 0 1 1 1 1 LsmAD domain Catalase PF00199.19 OQR95511.1 - 8.2e-07 28.4 0.0 0.12 11.4 0.0 3.7 4 0 0 4 4 4 2 Catalase Ank_2 PF12796.7 OQR95511.1 - 1.9e-06 28.4 0.1 5.3e-06 26.9 0.1 1.8 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQR95511.1 - 3.8e-05 24.1 0.1 0.00048 20.6 0.0 2.5 2 0 0 2 2 2 1 Ankyrin repeats (many copies) TPR_8 PF13181.6 OQR95511.1 - 4.2e-05 23.4 0.8 0.063 13.5 0.0 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat Ank_3 PF13606.6 OQR95511.1 - 0.00012 22.2 0.1 0.0015 18.8 0.0 2.7 2 0 0 2 2 2 1 Ankyrin repeat TPR_2 PF07719.17 OQR95511.1 - 0.00014 21.7 2.4 0.57 10.4 0.4 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat Ank_5 PF13857.6 OQR95511.1 - 0.00035 20.8 0.0 0.00087 19.6 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.30 OQR95511.1 - 0.00077 19.8 0.0 0.0031 17.9 0.0 2.1 2 0 0 2 2 1 1 Ankyrin repeat TPR_12 PF13424.6 OQR95511.1 - 0.027 14.7 2.8 0.66 10.3 2.8 2.9 1 1 0 1 1 1 0 Tetratricopeptide repeat TPR_1 PF00515.28 OQR95511.1 - 0.057 13.3 1.9 4.9 7.1 0.7 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_10 PF13374.6 OQR95511.1 - 0.12 12.3 0.6 2.1 8.4 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.6 OQR95511.1 - 0.14 12.3 0.8 13 6.1 0.3 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat GRIP PF01465.20 OQR95512.1 - 9.3e-17 60.7 0.0 2.9e-16 59.1 0.0 2.0 1 0 0 1 1 1 1 GRIP domain ANAPC4_WD40 PF12894.7 OQR95512.1 - 3.6e-12 46.4 1.2 0.0098 16.2 0.0 6.3 5 2 3 8 8 7 3 Anaphase-promoting complex subunit 4 WD40 domain SAP PF02037.27 OQR95512.1 - 5.4e-12 45.2 0.7 1.7e-11 43.6 0.7 2.0 1 0 0 1 1 1 1 SAP domain Tho1_MOS11_C PF18592.1 OQR95512.1 - 4.5e-05 23.2 18.6 6.2e-05 22.7 1.4 4.2 1 1 2 3 3 3 2 Tho1/MOS11 C-terminal domain Clathrin PF00637.20 OQR95512.1 - 0.00035 20.5 25.6 0.047 13.5 0.1 8.6 4 2 6 10 10 10 2 Region in Clathrin and VPS WD40 PF00400.32 OQR95512.1 - 0.0028 18.4 0.4 8 7.5 0.0 4.7 5 0 0 5 5 5 1 WD domain, G-beta repeat PPR PF01535.20 OQR95512.1 - 0.065 13.5 6.3 35 4.9 0.2 6.4 6 0 0 6 6 6 0 PPR repeat Phage_Cox PF10743.9 OQR95512.1 - 0.067 13.3 2.0 4.6 7.4 0.2 3.8 3 0 0 3 3 3 0 Regulatory phage protein cox zinc_ribbon_2 PF13240.6 OQR95512.1 - 0.13 12.0 4.0 0.33 10.7 4.0 1.7 1 0 0 1 1 1 0 zinc-ribbon domain DZR PF12773.7 OQR95512.1 - 0.39 10.8 9.3 0.85 9.7 9.3 1.6 1 0 0 1 1 1 0 Double zinc ribbon TPR_7 PF13176.6 OQR95512.1 - 0.43 10.7 20.9 4.2 7.6 1.1 9.0 8 3 1 9 9 9 0 Tetratricopeptide repeat TPR_2 PF07719.17 OQR95512.1 - 0.58 10.4 40.1 0.52 10.6 0.5 10.3 10 1 1 11 11 9 0 Tetratricopeptide repeat TPR_8 PF13181.6 OQR95512.1 - 3 8.3 10.4 1e+02 3.5 0.3 7.0 6 0 0 6 6 5 0 Tetratricopeptide repeat ubiquitin PF00240.23 OQR95514.1 - 1.1e-33 114.8 0.4 1.1e-33 114.8 0.4 1.6 2 0 0 2 2 2 1 Ubiquitin family Ribosomal_S27 PF01599.19 OQR95514.1 - 1.2e-26 92.6 3.3 1.2e-26 92.6 3.3 1.8 2 0 0 2 2 2 1 Ribosomal protein S27a Rad60-SLD PF11976.8 OQR95514.1 - 1.9e-15 56.5 0.7 1.9e-15 56.5 0.7 1.7 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 OQR95514.1 - 1.7e-05 25.2 0.3 0.00013 22.4 0.1 2.3 2 1 0 2 2 2 1 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 OQR95514.1 - 0.00038 20.5 0.4 0.00086 19.4 0.4 1.7 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_5 PF18037.1 OQR95514.1 - 0.0044 17.4 1.1 0.017 15.5 0.0 2.1 1 1 0 2 2 2 1 Ubiquitin-like domain DUF2407 PF10302.9 OQR95514.1 - 0.01 16.4 0.5 0.014 15.9 0.5 1.2 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain TBK1_ULD PF18396.1 OQR95514.1 - 0.011 15.6 0.0 0.017 15.1 0.0 1.3 1 0 0 1 1 1 0 TANK binding kinase 1 ubiquitin-like domain IBR PF01485.21 OQR95514.1 - 0.022 15.0 0.7 0.036 14.3 0.7 1.4 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain DUF373 PF04123.13 OQR95515.1 - 0.76 9.2 9.9 0.98 8.8 9.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF373) Cellulase PF00150.18 OQR95516.1 - 8.7e-13 48.3 3.6 1.5e-12 47.5 3.6 1.3 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) X8 PF07983.13 OQR95516.1 - 3.3e-09 37.3 1.3 1.2e-08 35.5 1.3 2.0 1 0 0 1 1 1 1 X8 domain Glyco_hydro_42 PF02449.15 OQR95516.1 - 0.00022 20.7 2.3 0.0097 15.3 1.3 2.1 2 0 0 2 2 2 2 Beta-galactosidase IL17R_fnIII_D1 PF16556.5 OQR95516.1 - 0.0089 15.7 0.0 0.021 14.5 0.0 1.5 1 0 0 1 1 1 1 Interleukin-17 receptor, fibronectin-III-like domain 1 TPR_2 PF07719.17 OQR95517.1 - 3.8e-23 79.7 18.0 0.0013 18.7 0.4 6.6 6 0 0 6 6 6 6 Tetratricopeptide repeat TPR_1 PF00515.28 OQR95517.1 - 2.1e-22 77.9 19.6 4.5e-05 23.1 0.0 6.4 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_11 PF13414.6 OQR95517.1 - 1.4e-11 43.9 7.1 3.2e-05 23.5 0.4 5.3 4 1 1 5 5 5 3 TPR repeat Nnf1 PF03980.14 OQR95517.1 - 1.2e-10 41.7 11.5 1e-09 38.7 7.4 2.6 2 0 0 2 2 2 1 Nnf1 TPR_8 PF13181.6 OQR95517.1 - 1.9e-08 33.9 14.7 0.21 11.9 0.1 6.8 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_9 PF13371.6 OQR95517.1 - 8.6e-08 32.2 5.7 1.2e-05 25.3 1.9 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 OQR95517.1 - 1.1e-05 25.7 13.2 0.00079 19.7 0.0 5.3 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_16 PF13432.6 OQR95517.1 - 2.6e-05 24.8 10.7 0.91 10.2 0.7 4.6 3 1 0 4 4 4 3 Tetratricopeptide repeat TPR_7 PF13176.6 OQR95517.1 - 0.0031 17.4 14.0 2.7 8.2 0.0 6.2 7 1 0 7 7 6 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 OQR95517.1 - 0.007 16.4 7.5 9.5 6.4 0.1 4.3 4 0 0 4 4 4 0 Fis1 C-terminal tetratricopeptide repeat zf-C4H2 PF10146.9 OQR95517.1 - 0.0079 16.5 2.9 0.23 11.8 0.7 2.4 2 0 0 2 2 2 1 Zinc finger-containing protein TPR_17 PF13431.6 OQR95517.1 - 0.015 15.6 8.4 1.2 9.6 0.1 4.6 4 1 0 4 4 4 0 Tetratricopeptide repeat Desmo_N PF06771.11 OQR95517.1 - 0.023 15.0 0.3 27 5.2 0.0 4.5 4 1 1 5 5 5 0 Viral Desmoplakin N-terminus Uso1_p115_C PF04871.13 OQR95517.1 - 0.024 15.0 0.7 0.024 15.0 0.7 2.1 2 0 0 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region MIT PF04212.18 OQR95517.1 - 0.089 12.9 8.0 8.2 6.6 0.0 4.4 4 0 0 4 4 4 0 MIT (microtubule interacting and transport) domain TilS PF09179.11 OQR95517.1 - 0.095 13.2 1.4 4.7 7.8 0.4 3.2 3 0 0 3 3 3 0 TilS substrate binding domain YkuI_C PF10388.9 OQR95517.1 - 0.23 11.3 2.0 0.39 10.5 0.3 2.2 2 0 0 2 2 2 0 EAL-domain associated signalling protein domain Arm-DNA-bind_5 PF17293.2 OQR95517.1 - 0.23 11.9 2.7 1.2 9.6 2.7 2.2 1 0 0 1 1 1 0 Arm DNA-binding domain TPR_14 PF13428.6 OQR95517.1 - 0.27 12.2 16.9 26 6.0 2.3 6.7 6 2 1 7 7 6 0 Tetratricopeptide repeat FapA PF03961.13 OQR95517.1 - 0.35 9.4 6.5 0.074 11.6 1.6 2.0 2 0 0 2 2 2 0 Flagellar Assembly Protein A DivIC PF04977.15 OQR95517.1 - 0.47 10.3 6.2 0.6 9.9 4.0 2.3 1 1 1 2 2 2 0 Septum formation initiator Nas2_N PF18265.1 OQR95517.1 - 0.96 9.4 4.1 8.8 6.3 0.0 3.2 3 0 0 3 3 3 0 Nas2 N_terminal domain TPR_6 PF13174.6 OQR95517.1 - 3 8.7 9.2 14 6.6 0.7 4.3 4 0 0 4 4 3 0 Tetratricopeptide repeat Spc24 PF08286.11 OQR95517.1 - 3.2 8.0 7.2 13 6.1 0.8 3.2 3 0 0 3 3 3 0 Spc24 subunit of Ndc80 SirA PF10747.9 OQR95518.1 - 0.065 13.6 0.2 0.36 11.2 0.0 2.0 2 0 0 2 2 2 0 Sporulation inhibitor of replication protein SirA DUF5598 PF18127.1 OQR95518.1 - 0.086 13.3 0.1 0.24 11.9 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF5598) UreD PF01774.17 OQR95518.1 - 0.11 12.4 0.0 0.15 11.9 0.0 1.3 1 0 0 1 1 1 0 UreD urease accessory protein Annexin PF00191.20 OQR95519.1 - 0.021 14.9 0.0 0.035 14.2 0.0 1.3 1 0 0 1 1 1 0 Annexin DUF5406 PF17400.2 OQR95519.1 - 0.12 12.7 0.0 0.18 12.2 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5406) MAPEG PF01124.18 OQR95520.1 - 0.00015 21.7 2.7 0.00021 21.2 2.7 1.3 1 0 0 1 1 1 1 MAPEG family Ank_4 PF13637.6 OQR95522.1 - 1.7e-50 168.8 23.2 3.1e-07 30.8 0.0 11.7 8 3 5 13 13 13 11 Ankyrin repeats (many copies) Ank_2 PF12796.7 OQR95522.1 - 3.4e-44 149.3 19.4 6.2e-08 33.1 0.2 7.6 2 2 5 7 7 7 7 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OQR95522.1 - 2e-43 145.9 32.5 0.00014 22.1 0.3 15.2 5 3 11 16 16 16 12 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQR95522.1 - 1.4e-27 92.6 10.2 2.6 8.9 0.0 15.5 15 1 2 17 17 17 7 Ankyrin repeat Ank PF00023.30 OQR95522.1 - 7e-10 38.9 4.1 13 6.5 0.2 11.0 6 2 0 6 6 6 1 Ankyrin repeat DUF1979 PF09322.10 OQR95522.1 - 0.00082 19.2 0.1 8.2 6.4 0.0 6.4 8 0 0 8 8 8 1 Domain of unknown function (DUF1979) DUF5049 PF16468.5 OQR95522.1 - 0.0015 18.4 5.6 26 4.8 0.0 8.7 9 3 3 12 12 12 0 Domain of unknown function (DUF5049) Methyltransf_32 PF13679.6 OQR95522.1 - 0.052 13.5 0.0 8.3 6.4 0.0 3.2 3 1 0 3 3 3 0 Methyltransferase domain Kinesin PF00225.23 OQR95523.1 - 3e-104 348.5 0.4 4e-104 348.1 0.4 1.1 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 OQR95523.1 - 4e-22 78.8 0.7 1.4e-21 77.0 0.1 2.3 2 0 0 2 2 2 1 Microtubule binding Kinesin_assoc PF16183.5 OQR95523.1 - 0.012 15.8 4.7 0.013 15.6 1.6 2.4 2 1 1 3 3 3 0 Kinesin-associated TMF_DNA_bd PF12329.8 OQR95523.1 - 0.081 12.9 6.6 0.046 13.7 1.5 2.7 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding Enkurin PF13864.6 OQR95523.1 - 0.11 12.9 2.8 0.39 11.2 2.8 1.9 1 1 0 1 1 1 0 Calmodulin-binding DUF2408 PF10303.9 OQR95523.1 - 0.33 11.5 3.1 3 8.4 0.9 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2408) FlxA PF14282.6 OQR95523.1 - 5.8 7.0 7.8 5.5 7.1 5.2 2.2 2 1 0 2 2 2 0 FlxA-like protein NAC PF01849.18 OQR95527.1 - 0.16 12.0 0.6 0.56 10.2 0.2 2.1 2 0 0 2 2 2 0 NAC domain FAT PF02259.23 OQR95529.1 - 9.4e-44 150.0 8.6 9.4e-44 150.0 8.6 2.7 2 0 0 2 2 2 1 FAT domain PI3_PI4_kinase PF00454.27 OQR95529.1 - 5.9e-17 62.3 2.1 1.4e-16 61.1 2.1 1.7 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.20 OQR95529.1 - 7.9e-05 22.4 0.2 0.00024 20.9 0.2 1.9 1 0 0 1 1 1 1 FATC domain MgrB PF13998.6 OQR95529.1 - 0.19 11.7 0.3 0.65 9.9 0.3 1.9 1 0 0 1 1 1 0 MgrB protein Tub PF01167.18 OQR95530.1 - 1.3e-75 254.3 0.1 2.7e-74 250.0 0.1 2.3 1 1 0 1 1 1 1 Tub family DUF3527 PF12043.8 OQR95530.1 - 0.0092 15.6 3.1 0.088 12.4 0.0 3.0 3 0 0 3 3 3 1 Domain of unknown function (DUF3527) DUF87 PF01935.17 OQR95531.1 - 0.084 12.9 0.4 0.12 12.5 0.4 1.1 1 0 0 1 1 1 0 Helicase HerA, central domain tRNA-synt_2c PF01411.19 OQR95532.1 - 4.5e-07 28.8 0.0 6.8e-07 28.2 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (A) tRNA_SAD PF07973.14 OQR95532.1 - 1.5e-06 28.1 0.2 3.8e-06 26.9 0.2 1.6 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain DHHA1 PF02272.19 OQR95532.1 - 0.0032 17.9 1.9 0.0063 16.9 1.9 1.5 1 0 0 1 1 1 1 DHHA1 domain YolD PF08863.10 OQR95532.1 - 0.02 14.9 0.0 0.057 13.5 0.0 1.7 1 0 0 1 1 1 0 YolD-like protein Myb_DNA-bind_6 PF13921.6 OQR95533.1 - 1.7e-35 121.0 7.9 1.2e-10 41.4 0.0 5.3 2 2 3 5 5 5 5 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 OQR95533.1 - 3.9e-29 100.6 7.1 1.7e-09 37.7 0.0 5.6 5 0 0 5 5 5 4 Myb-like DNA-binding domain Myb_DNA-bind_4 PF13837.6 OQR95533.1 - 5.2e-08 33.2 10.2 0.16 12.4 0.2 6.3 5 1 0 5 5 5 3 Myb/SANT-like DNA-binding domain SLIDE PF09111.10 OQR95533.1 - 2.8e-06 27.3 1.2 0.053 13.6 0.0 4.5 2 1 2 4 4 4 1 SLIDE MADF_DNA_bdg PF10545.9 OQR95533.1 - 2.3e-05 24.6 7.1 0.0047 17.2 0.1 4.5 5 0 0 5 5 5 2 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_2 PF08914.11 OQR95533.1 - 0.015 15.5 12.3 0.5 10.6 0.1 5.0 3 2 1 4 4 4 0 Rap1 Myb domain HrpB7 PF09486.10 OQR95533.1 - 0.068 13.6 0.9 0.22 11.9 0.9 1.9 1 0 0 1 1 1 0 Bacterial type III secretion protein (HrpB7) NPR2 PF06218.11 OQR95534.1 - 9.2e-90 301.5 2.8 5.8e-76 256.0 9.4 3.2 1 1 1 2 2 2 2 Nitrogen permease regulator 2 NIF PF03031.18 OQR95534.1 - 2.7e-24 85.7 0.2 5.6e-24 84.7 0.2 1.6 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase BRCT PF00533.26 OQR95534.1 - 0.00069 19.9 0.0 0.0025 18.2 0.0 2.1 1 1 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain RTT107_BRCT_5 PF16770.5 OQR95534.1 - 0.0014 18.5 0.0 0.0033 17.3 0.0 1.6 1 0 0 1 1 1 1 Regulator of Ty1 transposition protein 107 BRCT domain BRCT_2 PF16589.5 OQR95534.1 - 0.11 12.9 0.0 1.1 9.7 0.0 2.5 2 0 0 2 2 2 0 BRCT domain, a BRCA1 C-terminus domain Adaptin_N PF01602.20 OQR95536.1 - 2.5e-151 504.8 14.7 3.4e-151 504.4 14.7 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Isy1 PF06246.12 OQR95536.1 - 2.4e-67 227.2 6.7 4.7e-67 226.2 6.7 1.5 1 0 0 1 1 1 1 Isy1-like splicing family Cnd1 PF12717.7 OQR95536.1 - 3e-64 216.0 0.1 3e-64 216.0 0.1 3.9 3 1 1 4 4 4 1 non-SMC mitotic condensation complex subunit 1 B2-adapt-app_C PF09066.10 OQR95536.1 - 3.5e-20 72.2 0.0 1.6e-19 70.1 0.0 2.2 1 0 0 1 1 1 1 Beta2-adaptin appendage, C-terminal sub-domain HEAT_2 PF13646.6 OQR95536.1 - 3.5e-18 65.8 4.8 1e-08 35.5 0.0 5.8 2 2 3 5 5 5 5 HEAT repeats HEAT PF02985.22 OQR95536.1 - 1.5e-12 46.6 2.0 0.0017 18.4 0.0 5.9 5 0 0 5 5 5 2 HEAT repeat Arm PF00514.23 OQR95536.1 - 2.7e-07 30.4 1.3 0.0026 17.7 0.0 4.6 4 0 0 4 4 4 1 Armadillo/beta-catenin-like repeat Cnd3 PF12719.7 OQR95536.1 - 6.7e-07 28.8 1.4 0.00022 20.6 0.2 2.7 2 0 0 2 2 2 2 Nuclear condensing complex subunits, C-term domain Arm_2 PF04826.13 OQR95536.1 - 3.7e-05 23.3 0.0 0.00014 21.4 0.0 2.0 1 0 0 1 1 1 1 Armadillo-like CLASP_N PF12348.8 OQR95536.1 - 3.9e-05 23.3 0.6 0.54 9.8 0.0 3.6 2 1 1 3 3 3 2 CLASP N terminal HEAT_EZ PF13513.6 OQR95536.1 - 0.00039 20.9 0.6 4 8.1 0.0 4.6 4 0 0 4 4 4 2 HEAT-like repeat RTP1_C1 PF10363.9 OQR95536.1 - 0.0038 17.4 5.7 11 6.3 0.1 5.0 2 2 1 4 4 4 0 Required for nuclear transport of RNA pol II C-terminus 1 LZ3wCH PF18517.1 OQR95536.1 - 0.0066 16.5 0.4 0.027 14.6 0.4 2.1 1 0 0 1 1 1 1 Leucine zipper with capping helix domain UNC45-central PF11701.8 OQR95536.1 - 0.0069 16.4 1.3 0.72 9.8 0.0 3.6 3 1 0 3 3 3 1 Myosin-binding striated muscle assembly central Alpha_adaptinC2 PF02883.20 OQR95536.1 - 0.03 14.6 1.5 0.084 13.2 1.5 1.9 1 1 0 1 1 1 0 Adaptin C-terminal domain DUF5578 PF17741.1 OQR95536.1 - 0.16 11.3 5.2 8.2 5.8 0.1 4.1 4 1 0 4 4 4 0 Family of unknown function (DUF5578) Sec7_N PF12783.7 OQR95536.1 - 0.41 10.5 4.5 0.87 9.5 0.2 3.3 2 2 0 3 3 3 0 Guanine nucleotide exchange factor in Golgi transport N-terminal COX4 PF02936.14 OQR95538.1 - 3.5e-05 23.9 0.0 4.3e-05 23.5 0.0 1.2 1 1 0 1 1 1 1 Cytochrome c oxidase subunit IV DUF1138 PF06592.13 OQR95538.1 - 0.074 13.1 0.0 0.094 12.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1138) TPR_1 PF00515.28 OQR95539.1 - 3e-09 36.3 6.5 0.0014 18.3 0.0 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.6 OQR95539.1 - 1.7e-07 30.8 3.0 0.11 12.2 0.2 3.6 3 0 0 3 3 3 2 TPR repeat TPR_2 PF07719.17 OQR95539.1 - 6.8e-07 28.9 8.0 0.24 11.6 0.2 4.6 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_9 PF13371.6 OQR95539.1 - 1.8e-05 24.8 0.6 6.8e-05 22.9 0.6 2.0 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_3 PF07720.12 OQR95539.1 - 3.9e-05 23.5 4.8 0.012 15.6 0.0 2.8 3 0 0 3 3 2 2 Tetratricopeptide repeat TPR_19 PF14559.6 OQR95539.1 - 0.00011 22.6 3.4 0.42 11.2 0.2 3.4 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 OQR95539.1 - 0.00034 20.6 2.9 0.26 11.6 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 OQR95539.1 - 0.0014 19.3 1.1 4.9 8.3 0.1 4.2 2 1 1 3 3 3 1 Tetratricopeptide repeat NARP1 PF12569.8 OQR95539.1 - 0.0016 17.4 2.3 0.0016 17.4 2.3 2.6 1 1 2 3 3 2 1 NMDA receptor-regulated protein 1 TPR_12 PF13424.6 OQR95539.1 - 0.002 18.4 2.5 0.0031 17.8 0.3 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 OQR95539.1 - 0.0078 16.8 0.4 1.5 9.5 0.0 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat Arm PF00514.23 OQR95539.1 - 0.016 15.2 8.4 0.49 10.5 0.2 4.0 3 1 1 4 4 4 0 Armadillo/beta-catenin-like repeat Fis1_TPR_C PF14853.6 OQR95539.1 - 0.11 12.6 4.0 3.9 7.6 0.1 4.1 4 1 0 4 4 4 0 Fis1 C-terminal tetratricopeptide repeat TPR_17 PF13431.6 OQR95539.1 - 0.12 12.8 0.8 24 5.6 0.0 4.3 5 0 0 5 5 5 0 Tetratricopeptide repeat RPA_C PF08784.11 OQR95540.1 - 0.001 19.7 0.4 0.0039 17.8 0.4 1.9 1 1 0 1 1 1 1 Replication protein A C terminal DUF433 PF04255.14 OQR95540.1 - 0.0048 16.7 0.0 0.012 15.4 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF433) STN1_2 PF09170.10 OQR95540.1 - 0.0071 16.6 0.1 3 8.0 0.0 2.2 2 0 0 2 2 2 2 CST, Suppressor of cdc thirteen homolog, complex subunit STN1 DIL PF01843.19 OQR95540.1 - 0.094 13.0 0.1 0.23 11.7 0.1 1.6 1 0 0 1 1 1 0 DIL domain SDF PF00375.18 OQR95542.1 - 1.1e-69 235.4 36.7 3.3e-68 230.5 36.7 2.0 1 1 0 1 1 1 1 Sodium:dicarboxylate symporter family PglL_A PF15864.5 OQR95542.1 - 0.71 9.7 0.0 0.71 9.7 0.0 2.7 2 0 0 2 2 2 0 Protein glycosylation ligase Yip1 PF04893.17 OQR95542.1 - 8.4 6.1 28.6 0.44 10.3 4.8 3.2 3 0 0 3 3 3 0 Yip1 domain DUF4586 PF15239.6 OQR95543.1 - 0.0046 17.2 0.3 0.16 12.1 0.1 2.3 1 1 1 2 2 2 2 Domain of unknown function (DUF4586) Sel1 PF08238.12 OQR95546.1 - 2.4e-28 97.9 13.4 9.4e-05 23.0 0.2 8.6 8 0 0 8 8 8 7 Sel1 repeat TPR_1 PF00515.28 OQR95546.1 - 0.053 13.4 33.5 0.055 13.3 5.2 7.9 9 0 0 9 9 9 0 Tetratricopeptide repeat VSG_B PF13206.6 OQR95546.1 - 0.28 10.4 4.7 0.11 11.7 1.2 1.9 2 0 0 2 2 2 0 Trypanosomal VSG domain TPR_10 PF13374.6 OQR95546.1 - 0.47 10.4 3.5 0.6 10.1 0.8 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.6 OQR95546.1 - 1 10.1 17.1 14 6.6 0.0 6.1 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_16 PF13432.6 OQR95546.1 - 4.2 8.1 31.7 0.27 11.9 2.6 5.5 5 2 2 7 7 7 0 Tetratricopeptide repeat GAF PF01590.26 OQR95547.1 - 1.7e-05 25.5 0.0 4.6e-05 24.1 0.0 1.7 1 0 0 1 1 1 1 GAF domain FYVE PF01363.21 OQR95547.1 - 0.0016 18.5 13.8 0.0016 18.5 13.8 2.9 2 0 0 2 2 2 1 FYVE zinc finger WW PF00397.26 OQR95548.1 - 1.5 9.0 5.4 1.9 8.7 0.1 2.6 2 0 0 2 2 2 0 WW domain FYVE PF01363.21 OQR95549.1 - 1.4e-07 31.5 36.0 4.1e-05 23.6 12.4 2.7 2 0 0 2 2 2 2 FYVE zinc finger GRASP55_65 PF04495.14 OQR95550.1 - 3.3e-59 199.1 0.0 3.1e-43 147.4 0.0 2.2 1 1 1 2 2 2 2 GRASP55/65 PDZ-like domain PDZ_2 PF13180.6 OQR95550.1 - 0.02 15.2 0.0 1.5 9.2 0.0 2.4 2 0 0 2 2 2 0 PDZ domain Cyclin_N PF00134.23 OQR95551.1 - 5e-11 42.4 0.2 7.3e-09 35.4 0.0 2.3 2 0 0 2 2 2 2 Cyclin, N-terminal domain HscB_4_cys PF18256.1 OQR95552.1 - 0.00043 20.0 2.5 0.34 10.7 0.4 2.5 2 0 0 2 2 2 2 Co-chaperone HscB tetracysteine metal binding motif E7 PF00527.18 OQR95552.1 - 0.012 15.8 0.6 3.7 7.8 0.2 2.7 2 0 0 2 2 2 0 E7 protein, Early protein Tenui_NS3 PF05310.12 OQR95552.1 - 0.017 15.2 5.4 0.83 9.7 0.1 2.3 1 1 0 2 2 2 0 Tenuivirus movement protein ROS_MUCR PF05443.11 OQR95552.1 - 0.029 14.4 1.4 0.17 11.9 0.3 2.5 2 1 0 2 2 2 0 ROS/MUCR transcriptional regulator protein zf-FCS PF06467.14 OQR95552.1 - 0.031 14.2 7.4 1.3 9.0 0.5 3.0 3 0 0 3 3 3 0 MYM-type Zinc finger with FCS sequence motif DUF4296 PF14129.6 OQR95552.1 - 0.041 14.5 0.1 17 6.1 0.1 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4296) zf-ribbon_3 PF13248.6 OQR95552.1 - 0.051 13.0 3.2 3.5 7.2 0.1 2.7 3 0 0 3 3 3 0 zinc-ribbon domain HypA PF01155.19 OQR95552.1 - 0.41 10.7 4.1 6.6 6.8 0.2 2.8 3 0 0 3 3 3 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Sgf11 PF08209.11 OQR95552.1 - 0.71 9.5 9.6 5.7 6.6 0.1 4.2 3 1 0 3 3 3 0 Sgf11 (transcriptional regulation protein) RPA_interact_C PF14768.6 OQR95552.1 - 7.8 7.1 10.6 11 6.6 0.7 3.0 3 0 0 3 3 3 0 Replication protein A interacting C-terminal IQ PF00612.27 OQR95553.1 - 5e-05 22.7 17.2 0.016 14.9 2.1 4.2 4 0 0 4 4 4 3 IQ calmodulin-binding motif ABC1 PF03109.16 OQR95554.1 - 1.3e-35 122.1 0.6 1.1e-34 119.2 0.0 2.5 2 1 0 2 2 2 1 ABC1 family IFT57 PF10498.9 OQR95554.1 - 0.0012 17.9 3.2 0.0012 17.9 3.2 1.7 2 0 0 2 2 2 1 Intra-flagellar transport protein 57 Baculo_PEP_C PF04513.12 OQR95554.1 - 0.0037 17.3 5.5 0.0091 16.0 5.5 1.7 1 0 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus Transcrip_act PF04949.13 OQR95554.1 - 0.0045 16.9 0.1 0.01 15.7 0.1 1.5 1 1 0 1 1 1 1 Transcriptional activator Phasin PF05597.11 OQR95554.1 - 0.01 15.8 0.8 0.01 15.8 0.8 1.9 2 0 0 2 2 2 0 Poly(hydroxyalcanoate) granule associated protein (phasin) Tektin PF03148.14 OQR95554.1 - 0.012 14.4 2.9 0.011 14.5 1.8 1.4 1 1 0 1 1 1 0 Tektin family DUF1664 PF07889.12 OQR95554.1 - 0.019 15.0 4.3 0.065 13.3 3.6 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) DASH_Duo1 PF08651.10 OQR95554.1 - 0.023 14.5 1.9 1.6 8.6 0.3 2.7 1 1 1 2 2 2 0 DASH complex subunit Duo1 DUF1043 PF06295.12 OQR95554.1 - 0.054 13.5 9.1 0.037 14.0 7.0 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1043) CENP-F_leu_zip PF10473.9 OQR95554.1 - 0.065 13.3 8.1 0.14 12.2 8.1 1.5 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 AAA_13 PF13166.6 OQR95554.1 - 0.082 11.5 5.2 0.12 11.0 5.2 1.2 1 0 0 1 1 1 0 AAA domain MCPsignal PF00015.21 OQR95554.1 - 0.082 12.7 6.6 0.088 12.6 5.3 1.7 1 1 1 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Spc7 PF08317.11 OQR95554.1 - 0.097 11.5 7.2 0.21 10.4 7.2 1.5 1 0 0 1 1 1 0 Spc7 kinetochore protein PMC2NT PF08066.12 OQR95554.1 - 0.099 13.3 0.8 1.5 9.6 0.0 2.6 2 0 0 2 2 2 0 PMC2NT (NUC016) domain DASH_Dad1 PF08649.10 OQR95554.1 - 0.1 12.8 2.5 2.4 8.4 0.2 2.9 2 1 1 3 3 2 0 DASH complex subunit Dad1 V_ATPase_I PF01496.19 OQR95554.1 - 0.1 10.5 0.8 0.14 10.0 0.8 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4200 PF13863.6 OQR95554.1 - 0.12 12.8 2.3 0.32 11.4 2.3 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) DUF3584 PF12128.8 OQR95554.1 - 0.13 9.7 6.2 0.18 9.3 6.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) MIP-T3_C PF17749.1 OQR95554.1 - 0.14 12.1 9.9 0.099 12.6 7.7 1.8 2 0 0 2 2 2 0 Microtubule-binding protein MIP-T3 C-terminal region IMD PF08397.11 OQR95554.1 - 0.15 11.5 2.0 0.18 11.2 0.8 1.7 2 0 0 2 2 1 0 IRSp53/MIM homology domain Arfaptin PF06456.13 OQR95554.1 - 0.19 11.2 2.4 1.4 8.5 1.8 2.1 1 1 0 1 1 1 0 Arfaptin-like domain ALMT PF11744.8 OQR95554.1 - 0.2 10.5 1.3 0.29 9.9 1.3 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter KxDL PF10241.9 OQR95554.1 - 0.21 11.9 6.7 0.18 12.1 1.4 2.6 1 1 1 2 2 2 0 Uncharacterized conserved protein DUF812 PF05667.11 OQR95554.1 - 0.23 10.3 10.7 0.35 9.7 10.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) Prominin PF05478.11 OQR95554.1 - 0.29 9.1 3.0 0.45 8.4 3.0 1.2 1 0 0 1 1 1 0 Prominin Exonuc_VII_L PF02601.15 OQR95554.1 - 0.33 10.5 5.7 0.59 9.6 5.7 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit BORCS7 PF16088.5 OQR95554.1 - 0.34 11.2 3.9 0.36 11.1 2.2 2.0 1 1 0 1 1 1 0 BLOC-1-related complex sub-unit 7 DUF948 PF06103.11 OQR95554.1 - 0.37 11.1 9.7 5.2 7.4 2.3 3.3 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF948) SKA1 PF07160.12 OQR95554.1 - 0.38 10.6 7.5 0.85 9.4 7.5 1.5 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 1 Laminin_II PF06009.12 OQR95554.1 - 0.47 10.5 9.3 4.6 7.2 9.2 2.3 1 1 0 1 1 1 0 Laminin Domain II COG6 PF06419.11 OQR95554.1 - 0.5 8.5 6.5 0.66 8.1 4.4 1.9 1 1 1 2 2 2 0 Conserved oligomeric complex COG6 DUF2884 PF11101.8 OQR95554.1 - 0.5 9.8 9.3 2.1 7.8 8.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2884) Muted PF14942.6 OQR95554.1 - 0.52 10.6 6.7 0.92 9.9 5.9 1.9 1 1 0 1 1 1 0 Organelle biogenesis, Muted-like protein Allexi_40kDa PF05549.11 OQR95554.1 - 0.54 9.7 4.8 1 8.8 4.8 1.5 1 0 0 1 1 1 0 Allexivirus 40kDa protein HIP1_clath_bdg PF16515.5 OQR95554.1 - 0.64 10.7 10.5 0.64 10.7 6.6 2.5 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 TBCC_N PF16752.5 OQR95554.1 - 0.67 10.4 4.5 1.3 9.5 3.6 1.9 1 1 1 2 2 1 0 Tubulin-specific chaperone C N-terminal domain DASH_Dad2 PF08654.10 OQR95554.1 - 1.1 9.8 6.0 1.5 9.3 4.5 2.0 1 1 0 1 1 1 0 DASH complex subunit Dad2 Baculo_p24 PF05073.12 OQR95554.1 - 1.1 9.0 4.0 2.3 8.0 4.0 1.5 1 0 0 1 1 1 0 Baculovirus P24 capsid protein Prefoldin_2 PF01920.20 OQR95554.1 - 1.3 9.0 5.9 1.7 8.6 0.2 2.7 1 1 1 2 2 2 0 Prefoldin subunit Phage_GPO PF05929.11 OQR95554.1 - 1.3 8.6 5.8 1.4 8.5 4.6 1.6 1 1 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase GAS PF13851.6 OQR95554.1 - 1.5 8.2 6.8 1.7 8.0 2.1 2.4 2 1 1 3 3 2 0 Growth-arrest specific micro-tubule binding COG2 PF06148.11 OQR95554.1 - 2.3 8.3 5.3 4.4 7.4 3.2 2.4 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 AIP3 PF03915.13 OQR95554.1 - 2.4 7.1 8.9 9.2 5.2 8.9 1.8 1 1 0 1 1 1 0 Actin interacting protein 3 NPV_P10 PF05531.12 OQR95554.1 - 3.6 8.1 9.1 7.5 7.1 4.8 3.0 1 1 2 3 3 3 0 Nucleopolyhedrovirus P10 protein YkyA PF10368.9 OQR95554.1 - 4.5 6.9 8.8 1.1 8.9 1.0 2.5 1 1 2 3 3 3 0 Putative cell-wall binding lipoprotein Fib_alpha PF08702.10 OQR95554.1 - 5.3 7.2 7.4 10 6.3 5.2 1.9 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family DUF148 PF02520.17 OQR95554.1 - 9.8 6.3 10.1 17 5.5 9.0 1.9 1 1 1 2 2 2 0 Domain of unknown function DUF148 ASC PF00858.24 OQR95555.1 - 0.13 11.2 0.0 0.39 9.6 0.0 1.7 1 0 0 1 1 1 0 Amiloride-sensitive sodium channel IMPDH PF00478.25 OQR95556.1 - 8.9e-83 278.1 5.9 7.1e-82 275.2 5.9 1.9 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 OQR95556.1 - 6.5e-06 25.4 0.4 1e-05 24.8 0.4 1.3 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Aldolase PF01081.19 OQR95556.1 - 0.049 13.0 0.7 0.18 11.2 0.1 2.0 1 1 1 2 2 2 0 KDPG and KHG aldolase His_biosynth PF00977.21 OQR95556.1 - 0.055 12.9 0.9 3 7.2 0.1 2.2 2 0 0 2 2 2 0 Histidine biosynthesis protein MORN PF02493.20 OQR95557.1 - 1.3e-39 131.8 50.5 8e-08 31.7 0.2 8.7 9 0 0 9 9 9 8 MORN repeat PrsW-protease PF13367.6 OQR95558.1 - 1.1e-18 67.3 8.4 5.5e-18 65.1 8.4 2.1 1 1 0 1 1 1 1 PrsW family intramembrane metalloprotease DUF4064 PF13273.6 OQR95558.1 - 0.066 13.5 0.5 0.066 13.5 0.5 2.6 3 1 1 4 4 4 0 Protein of unknown function (DUF4064) LSM PF01423.22 OQR95559.1 - 1.1e-14 53.8 0.1 1.4e-14 53.5 0.1 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 OQR95559.1 - 0.011 15.8 0.1 0.023 14.8 0.0 1.6 2 0 0 2 2 2 0 Ataxin 2 SM domain Tail_tube PF10618.9 OQR95559.1 - 0.18 11.7 0.0 0.25 11.2 0.0 1.4 1 1 0 1 1 1 0 Phage tail tube protein DPBB_1 PF03330.18 OQR95560.1 - 0.0019 18.5 0.8 0.0053 17.0 0.6 2.0 1 1 0 1 1 1 1 Lytic transglycolase DUF2614 PF11023.8 OQR95560.1 - 0.008 16.3 0.2 0.024 14.7 0.2 1.8 1 0 0 1 1 1 1 Zinc-ribbon containing domain HypA PF01155.19 OQR95560.1 - 0.044 13.8 3.7 0.093 12.8 3.7 1.5 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Porin_3 PF01459.22 OQR95560.1 - 0.25 10.8 3.4 0.19 11.2 1.4 1.7 2 0 0 2 2 2 0 Eukaryotic porin AA_permease_2 PF13520.6 OQR95561.1 - 5.3e-14 51.9 49.8 5.3e-14 51.9 49.8 2.7 2 1 0 2 2 2 1 Amino acid permease AA_permease PF00324.21 OQR95561.1 - 2.7e-09 36.2 48.1 2.7e-09 36.2 48.1 3.4 3 1 0 3 3 3 1 Amino acid permease DUF3040 PF11239.8 OQR95562.1 - 0.053 13.8 0.4 0.082 13.2 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3040) DUF3169 PF11368.8 OQR95562.1 - 0.82 9.1 7.5 1.1 8.7 7.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3169) Trm56 PF01994.16 OQR95563.1 - 0.0011 18.9 2.2 0.62 10.0 0.1 2.5 3 0 0 3 3 3 2 tRNA ribose 2'-O-methyltransferase, aTrm56 NDK PF00334.19 OQR95564.1 - 4e-28 98.1 0.0 1.3e-26 93.2 0.0 2.4 2 1 0 2 2 2 1 Nucleoside diphosphate kinase DUF1126 PF06565.12 OQR95564.1 - 7.1e-06 25.8 0.3 1.8e-05 24.5 0.3 1.7 1 1 0 1 1 1 1 DUF1126 PH-like domain AA_permease_2 PF13520.6 OQR95565.1 - 2.1e-16 59.8 87.1 2.2e-14 53.2 46.6 4.1 3 1 1 4 4 4 3 Amino acid permease AA_permease PF00324.21 OQR95565.1 - 3.8e-08 32.4 40.9 3.8e-08 32.4 40.9 4.0 3 1 1 4 4 4 3 Amino acid permease putAbiC PF16872.5 OQR95565.1 - 0.033 14.9 1.1 8.7 7.1 0.0 2.9 3 0 0 3 3 3 0 Putative phage abortive infection protein DUP PF00674.18 OQR95565.1 - 0.045 13.9 0.1 3.2 7.9 0.0 3.3 2 0 0 2 2 2 0 DUP family DUF3290 PF11694.8 OQR95565.1 - 1.8 8.6 7.1 1.5 8.8 0.1 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3290) PITH PF06201.13 OQR95566.1 - 1.1e-36 126.3 0.1 1.3e-36 126.1 0.1 1.0 1 0 0 1 1 1 1 PITH domain DUF2247 PF10004.9 OQR95567.1 - 0.13 12.0 1.8 0.29 10.9 1.8 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2247) DUF2408 PF10303.9 OQR95567.1 - 0.91 10.1 13.0 1.1 9.9 1.5 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF2408) YtxH PF12732.7 OQR95567.1 - 1.6 9.3 7.3 2e+02 2.6 7.3 3.2 1 1 0 1 1 1 0 YtxH-like protein CorA PF01544.18 OQR95567.1 - 7.1 5.9 11.5 0.76 9.0 1.0 2.1 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein Annexin PF00191.20 OQR95568.1 - 5e-53 177.1 0.3 6.9e-13 48.5 0.0 4.2 4 0 0 4 4 4 4 Annexin TetR_C_28 PF17937.1 OQR95568.1 - 0.11 13.0 0.0 29 5.2 0.0 3.8 5 0 0 5 5 5 0 Tetracyclin repressor-like, C-terminal domain Annexin_like PF18411.1 OQR95568.1 - 0.13 12.6 0.0 0.28 11.5 0.0 1.6 1 0 0 1 1 1 0 Annexin-like domain TPH PF13868.6 OQR95569.1 - 5.1e-44 150.2 140.0 5.1e-44 150.2 140.0 2.2 1 1 1 2 2 2 1 Trichohyalin-plectin-homology domain stn_TNFRSF12A PF12191.8 OQR95570.1 - 0.0064 16.7 0.1 0.014 15.7 0.1 1.6 1 0 0 1 1 1 1 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain TMIE PF16038.5 OQR95570.1 - 0.15 11.9 0.3 0.25 11.2 0.3 1.3 1 0 0 1 1 1 0 TMIE protein Elong_Iki1 PF10483.9 OQR95571.1 - 2.8e-05 23.8 1.8 3.8e-05 23.4 1.8 1.3 1 1 0 1 1 1 1 Elongator subunit Iki1 WW PF00397.26 OQR95572.1 - 2.8e-07 30.5 1.3 4.6e-07 29.8 1.3 1.3 1 0 0 1 1 1 1 WW domain zf-ACC PF17848.1 OQR95572.1 - 0.11 12.6 0.0 0.11 12.6 0.0 2.3 3 0 0 3 3 3 0 Acetyl-coA carboxylase zinc finger domain zf-CRD PF17979.1 OQR95572.1 - 0.93 9.6 6.1 0.13 12.3 0.8 2.1 1 1 1 2 2 2 0 Cysteine rich domain with multizinc binding regions zf-P11 PF03854.14 OQR95572.1 - 1 9.1 4.7 4.1 7.1 4.7 2.0 1 1 0 1 1 1 0 P-11 zinc finger APG6 PF04111.12 OQR95573.1 - 6.1e-59 199.0 0.0 1e-58 198.3 0.0 1.3 1 0 0 1 1 1 1 Apg6 BARA domain APG6_N PF17675.1 OQR95573.1 - 1.9e-08 34.9 5.2 3.2e-08 34.2 5.2 1.4 1 0 0 1 1 1 1 Apg6 coiled-coil region DUF410 PF04190.13 OQR95573.1 - 0.0035 17.2 1.7 0.017 14.9 0.1 2.4 3 0 0 3 3 3 1 Protein of unknown function (DUF410) YdjO PF14169.6 OQR95573.1 - 0.15 11.8 1.5 4.2 7.2 0.1 2.9 3 0 0 3 3 3 0 Cold-inducible protein YdjO FUN14 PF04930.15 OQR95574.1 - 1.8e-24 86.0 0.2 2.8e-24 85.4 0.2 1.3 1 0 0 1 1 1 1 FUN14 family EF-hand_6 PF13405.6 OQR95574.1 - 0.035 14.0 0.4 0.087 12.8 0.4 1.6 1 0 0 1 1 1 0 EF-hand domain Dockerin_1 PF00404.18 OQR95574.1 - 0.037 14.2 0.2 0.073 13.3 0.2 1.5 1 0 0 1 1 1 0 Dockerin type I domain EF-hand_5 PF13202.6 OQR95574.1 - 0.098 12.2 0.9 0.3 10.6 0.4 2.0 2 0 0 2 2 2 0 EF hand EF-hand_1 PF00036.32 OQR95574.1 - 0.17 11.5 1.5 0.26 10.9 0.6 1.8 2 0 0 2 2 2 0 EF hand Ank_2 PF12796.7 OQR95575.1 - 3e-26 91.8 11.0 5e-13 49.5 0.1 4.1 2 2 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQR95575.1 - 1.3e-21 76.6 5.7 1.4e-09 38.3 0.0 6.8 2 1 6 8 8 8 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQR95575.1 - 9.4e-17 59.4 8.0 0.0001 22.4 0.0 8.1 7 0 0 7 7 7 4 Ankyrin repeat Ank PF00023.30 OQR95575.1 - 1.3e-15 57.0 10.1 2.4e-07 30.9 0.0 7.6 6 1 0 6 6 6 3 Ankyrin repeat Ank_5 PF13857.6 OQR95575.1 - 3.5e-14 52.7 5.7 2.7e-05 24.4 0.0 5.4 4 1 1 5 5 5 2 Ankyrin repeats (many copies) Ion_trans PF00520.31 OQR95575.1 - 4.5e-07 29.3 28.8 4.5e-07 29.3 28.8 3.0 1 1 2 3 3 3 1 Ion transport protein T2SSE PF00437.20 OQR95576.1 - 8.1e-06 25.1 0.0 1.4e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein DUF87 PF01935.17 OQR95576.1 - 0.0035 17.5 0.1 0.064 13.3 0.0 2.2 2 0 0 2 2 2 1 Helicase HerA, central domain ResIII PF04851.15 OQR95576.1 - 0.0083 16.1 0.1 0.032 14.2 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit RHSP PF07999.11 OQR95576.1 - 0.14 10.9 0.0 1.9 7.2 0.0 2.3 2 0 0 2 2 2 0 Retrotransposon hot spot protein Astacin PF01400.24 OQR95579.1 - 4.1e-21 75.5 3.1 4.4e-19 68.9 3.1 2.7 1 1 0 1 1 1 1 Astacin (Peptidase family M12A) TMEM214 PF10151.9 OQR95579.1 - 2 6.8 20.8 2.7 6.3 20.8 1.1 1 0 0 1 1 1 0 TMEM214, C-terminal, caspase 4 activator Astacin PF01400.24 OQR95580.1 - 1.7e-14 53.9 4.0 2.9e-12 46.6 4.0 3.0 1 1 0 1 1 1 1 Astacin (Peptidase family M12A) Peptidase_M41 PF01434.18 OQR95580.1 - 0.033 14.0 1.0 0.063 13.1 1.0 1.3 1 0 0 1 1 1 0 Peptidase family M41 ETRAMP PF09716.10 OQR95580.1 - 0.1 12.6 0.3 0.14 12.2 0.3 1.7 1 1 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) VPS13_C PF16909.5 OQR95581.1 - 4.2e-47 160.2 5.0 8.7e-44 149.4 0.0 3.6 4 0 0 4 4 4 2 Vacuolar-sorting-associated 13 protein C-terminal SHR-BD PF06650.12 OQR95581.1 - 8.1e-25 87.7 0.1 1.9e-24 86.5 0.1 1.6 1 0 0 1 1 1 1 SHR-binding domain of vacuolar-sorting associated protein 13 VPS13_mid_rpt PF16910.5 OQR95581.1 - 1.2e-21 77.3 1.7 1.9e-20 73.3 1.1 3.0 2 1 0 2 2 2 1 Repeating coiled region of VPS13 PX PF00787.24 OQR95581.1 - 3.4e-18 65.7 0.5 7.3e-18 64.6 0.5 1.6 1 0 0 1 1 1 1 PX domain C2 PF00168.30 OQR95581.1 - 0.00028 21.1 0.0 0.0016 18.7 0.0 2.4 2 0 0 2 2 2 1 C2 domain PDZ PF00595.24 OQR95581.1 - 0.0021 18.4 0.1 0.0079 16.5 0.0 2.1 2 0 0 2 2 2 1 PDZ domain ATG_C PF09333.11 OQR95581.1 - 0.013 15.8 0.0 0.14 12.5 0.0 2.5 2 0 0 2 2 2 0 Autophagy-related protein C terminal domain PDZ_6 PF17820.1 OQR95581.1 - 0.096 12.5 0.0 0.24 11.2 0.0 1.7 1 0 0 1 1 1 0 PDZ domain Astacin PF01400.24 OQR95582.1 - 3.3e-09 36.7 2.8 0.0081 15.8 0.1 3.8 1 1 0 2 2 2 2 Astacin (Peptidase family M12A) Pro_CA PF00484.19 OQR95583.1 - 5.8e-48 163.1 1.5 5.8e-48 163.1 1.5 2.0 2 0 0 2 2 2 1 Carbonic anhydrase Adap_comp_sub PF00928.21 OQR95583.1 - 9.1e-23 81.0 0.0 3.6e-22 79.0 0.0 1.8 2 0 0 2 2 2 1 Adaptor complexes medium subunit family Aminotran_1_2 PF00155.21 OQR95585.1 - 2.5e-47 161.8 0.1 2.9e-47 161.6 0.1 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 OQR95585.1 - 2.9e-07 29.4 0.0 4.1e-07 28.9 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 OQR95585.1 - 0.0033 16.4 0.1 0.016 14.2 0.0 2.0 2 0 0 2 2 2 1 Aminotransferase class-V Aminotran_3 PF00202.21 OQR95585.1 - 0.0034 16.1 0.0 0.0046 15.7 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-III DegT_DnrJ_EryC1 PF01041.17 OQR95585.1 - 0.0091 15.3 0.1 0.018 14.4 0.1 1.4 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family OKR_DC_1 PF01276.20 OQR95585.1 - 0.021 13.6 0.1 0.053 12.2 0.1 1.6 1 1 0 1 1 1 0 Orn/Lys/Arg decarboxylase, major domain LRR_8 PF13855.6 OQR95586.1 - 2.2e-07 30.6 2.5 2.2e-07 30.6 2.5 2.8 2 1 0 2 2 2 1 Leucine rich repeat LRR_4 PF12799.7 OQR95586.1 - 3.7e-05 24.0 6.2 0.0015 18.9 0.1 3.4 3 1 1 4 4 4 2 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 OQR95586.1 - 0.014 15.4 2.9 2.4 8.4 0.1 4.0 3 0 0 3 3 3 0 Leucine Rich repeat LRR_9 PF14580.6 OQR95586.1 - 0.032 13.7 0.4 0.29 10.6 0.2 2.3 2 0 0 2 2 2 0 Leucine-rich repeat Endonuc-BglII PF09195.11 OQR95586.1 - 0.08 12.8 0.0 0.16 11.8 0.0 1.5 1 0 0 1 1 1 0 Restriction endonuclease BglII LRR_1 PF00560.33 OQR95586.1 - 0.56 11.0 8.4 5 8.1 0.0 4.6 4 1 1 5 5 5 0 Leucine Rich Repeat Glyco_transf_41 PF13844.6 OQR95589.1 - 5.8e-22 77.8 0.1 9.2e-22 77.1 0.1 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 41 Glycos_transf_1 PF00534.20 OQR95589.1 - 2.5e-06 27.1 0.0 5.4e-06 26.1 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 OQR95589.1 - 3.7e-06 27.4 0.0 0.0001 22.7 0.0 2.4 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 OQR95589.1 - 0.00015 21.8 0.1 0.00069 19.7 0.0 2.2 2 0 0 2 2 2 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.6 OQR95589.1 - 0.00021 21.8 0.2 0.33 11.4 0.0 2.5 2 0 0 2 2 2 2 Glycosyl transferase 4-like domain DpnII PF04556.12 OQR95589.1 - 0.018 14.4 0.1 0.04 13.2 0.1 1.5 1 0 0 1 1 1 0 DpnII restriction endonuclease Ribosomal_L17 PF01196.19 OQR95589.1 - 0.11 13.4 0.0 0.43 11.5 0.0 2.1 1 0 0 1 1 1 0 Ribosomal protein L17 TPR_17 PF13431.6 OQR95589.1 - 8 7.1 6.5 4.4 7.9 0.1 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat FYVE PF01363.21 OQR95590.1 - 1.1e-13 51.1 17.8 1.4e-13 50.8 17.8 1.1 1 0 0 1 1 1 1 FYVE zinc finger zinc_ribbon_9 PF14369.6 OQR95590.1 - 1.9 8.8 15.4 0.12 12.7 3.8 2.7 3 0 0 3 3 3 0 zinc-ribbon Rab3-GTPase_cat PF13890.6 OQR95592.1 - 2.6e-50 170.2 2.0 4e-50 169.6 2.0 1.3 1 0 0 1 1 1 1 Rab3 GTPase-activating protein catalytic subunit B-block_TFIIIC PF04182.12 OQR95593.1 - 1.7e-06 28.1 0.2 1.9e-05 24.7 0.0 2.7 2 0 0 2 2 2 1 B-block binding subunit of TFIIIC Pkinase_Tyr PF07714.17 OQR95594.1 - 1.7e-14 53.7 0.2 5.5e-13 48.8 0.1 2.4 1 1 1 2 2 2 1 Protein tyrosine kinase C2 PF00168.30 OQR95594.1 - 1.1e-06 28.9 0.0 2.3e-06 27.8 0.0 1.6 1 0 0 1 1 1 1 C2 domain Pkinase PF00069.25 OQR95594.1 - 2.5e-06 27.1 0.0 4.6e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 OQR95594.1 - 0.019 14.4 0.1 0.052 12.9 0.1 1.7 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Nsp1_C PF05064.13 OQR95594.1 - 0.14 11.9 3.5 0.42 10.4 3.5 1.7 1 0 0 1 1 1 0 Nsp1-like C-terminal region ERM PF00769.19 OQR95594.1 - 0.17 11.7 3.9 0.28 11.0 3.9 1.2 1 0 0 1 1 1 0 Ezrin/radixin/moesin family SWIRM-assoc_1 PF16495.5 OQR95594.1 - 0.37 10.8 3.2 0.93 9.5 3.2 1.6 1 0 0 1 1 1 0 SWIRM-associated region 1 FGF PF00167.18 OQR95598.1 - 0.045 13.9 0.0 0.091 12.9 0.0 1.4 1 0 0 1 1 1 0 Fibroblast growth factor TMEM223 PF14640.6 OQR95599.1 - 9.6e-20 71.4 0.0 1.8e-19 70.5 0.0 1.3 1 0 0 1 1 1 1 Transmembrane protein 223 MM_CoA_mutase PF01642.22 OQR95600.1 - 2.5e-235 781.9 0.3 3.1e-235 781.6 0.3 1.1 1 0 0 1 1 1 1 Methylmalonyl-CoA mutase B12-binding PF02310.19 OQR95600.1 - 1.3e-14 54.3 0.1 4.4e-14 52.6 0.1 1.9 2 0 0 2 2 2 1 B12 binding domain SNARE_assoc PF09335.11 OQR95600.1 - 1.6e-08 35.0 14.8 1.5e-05 25.4 14.8 3.4 2 1 0 2 2 2 1 SNARE associated Golgi protein Ketoacyl-synt_2 PF13723.6 OQR95600.1 - 0.0016 18.1 0.0 0.0043 16.7 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Saf_2TM PF18303.1 OQR95600.1 - 0.099 12.2 0.1 0.26 10.9 0.1 1.6 1 0 0 1 1 1 0 SAVED-fused 2TM effector domain bZIP_1 PF00170.21 OQR95601.1 - 0.0017 18.4 8.4 0.097 12.8 1.6 2.5 1 1 0 2 2 2 2 bZIP transcription factor FlaC_arch PF05377.11 OQR95601.1 - 0.006 17.0 2.0 0.093 13.1 0.2 2.4 2 0 0 2 2 2 1 Flagella accessory protein C (FlaC) Shugoshin_N PF07558.11 OQR95601.1 - 0.0083 16.0 4.3 0.089 12.7 0.1 2.9 2 1 1 3 3 3 1 Shugoshin N-terminal coiled-coil region Atg14 PF10186.9 OQR95601.1 - 0.014 14.5 7.7 0.016 14.3 7.7 1.0 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF4780 PF16012.5 OQR95601.1 - 0.023 14.2 1.5 0.026 14.0 1.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4780) DUF4618 PF15397.6 OQR95601.1 - 0.028 13.8 13.1 0.069 12.6 6.5 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4618) GAS PF13851.6 OQR95601.1 - 0.037 13.4 12.7 0.046 13.1 12.7 1.2 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding TMF_TATA_bd PF12325.8 OQR95601.1 - 0.052 13.8 10.0 0.047 13.9 9.0 1.4 1 1 0 1 1 1 0 TATA element modulatory factor 1 TATA binding ROQ_II PF18386.1 OQR95601.1 - 0.064 13.1 1.4 0.068 13.0 0.3 1.7 2 0 0 2 2 1 0 Roquin II domain HALZ PF02183.18 OQR95601.1 - 0.07 13.4 7.8 0.41 10.9 1.0 3.0 3 0 0 3 3 3 0 Homeobox associated leucine zipper Syntaxin-6_N PF09177.11 OQR95601.1 - 0.071 13.7 5.1 0.12 13.0 4.9 1.4 1 1 0 1 1 1 0 Syntaxin 6, N-terminal DMPK_coil PF08826.10 OQR95601.1 - 0.098 12.8 10.2 0.27 11.3 0.8 2.5 1 1 1 2 2 2 0 DMPK coiled coil domain like WD40_alt PF14077.6 OQR95601.1 - 0.1 12.5 0.1 2.3 8.2 0.0 2.3 2 0 0 2 2 2 0 Alternative WD40 repeat motif Jnk-SapK_ap_N PF09744.9 OQR95601.1 - 0.12 12.6 15.6 0.16 12.2 15.6 1.1 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 UPF0242 PF06785.11 OQR95601.1 - 0.15 12.1 12.3 0.34 11.0 12.4 1.5 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Cnn_1N PF07989.11 OQR95601.1 - 0.18 12.0 11.2 0.2 11.9 3.8 2.3 1 1 1 2 2 2 0 Centrosomin N-terminal motif 1 ZapB PF06005.12 OQR95601.1 - 0.21 12.1 15.0 0.26 11.7 2.9 2.6 1 1 1 2 2 2 0 Cell division protein ZapB NPV_P10 PF05531.12 OQR95601.1 - 0.26 11.8 4.4 0.49 10.9 4.4 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein Retrotrans_gag PF03732.17 OQR95601.1 - 0.3 11.4 10.2 0.47 10.8 1.8 2.3 1 1 1 2 2 2 0 Retrotransposon gag protein Csm1_N PF18504.1 OQR95601.1 - 0.3 11.4 10.6 0.2 12.0 3.6 2.4 1 1 1 2 2 2 0 Csm1 N-terminal domain TMPIT PF07851.13 OQR95601.1 - 0.53 9.5 8.2 0.66 9.2 8.2 1.0 1 0 0 1 1 1 0 TMPIT-like protein BLOC1_2 PF10046.9 OQR95601.1 - 0.55 10.6 9.9 1.6 9.1 7.5 2.2 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Agouti PF05039.12 OQR95601.1 - 0.61 10.8 2.8 0.5 11.1 1.4 1.6 1 1 1 2 2 2 0 Agouti protein CorA PF01544.18 OQR95601.1 - 0.63 9.3 6.7 0.7 9.2 6.7 1.1 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein bZIP_2 PF07716.15 OQR95601.1 - 0.78 9.9 16.4 1.8 8.7 4.3 3.2 3 1 1 4 4 4 0 Basic region leucine zipper FAM76 PF16046.5 OQR95601.1 - 0.87 8.9 6.2 1 8.7 6.2 1.1 1 0 0 1 1 1 0 FAM76 protein TSNAXIP1_N PF15739.5 OQR95601.1 - 0.93 9.9 11.0 10 6.6 10.9 2.0 1 1 0 1 1 1 0 Translin-associated factor X-interacting N-terminus GIT_CC PF16559.5 OQR95601.1 - 2.6 8.0 14.7 0.6 10.0 1.2 2.5 2 1 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor FapA PF03961.13 OQR95601.1 - 3.3 6.2 7.9 3.7 6.1 7.9 1.0 1 0 0 1 1 1 0 Flagellar Assembly Protein A DivIC PF04977.15 OQR95601.1 - 5.5 6.8 12.6 17 5.3 3.7 2.5 1 1 1 2 2 2 0 Septum formation initiator Exonuc_VII_L PF02601.15 OQR95601.1 - 5.9 6.4 10.3 6.7 6.2 10.3 1.0 1 0 0 1 1 1 0 Exonuclease VII, large subunit NYD-SP28_assoc PF14775.6 OQR95601.1 - 6.5 6.9 14.9 5.8 7.1 2.7 3.3 1 1 1 2 2 2 0 Sperm tail C-terminal domain AAA PF00004.29 OQR95602.1 - 4.8e-41 140.3 0.0 5.9e-34 117.3 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 OQR95602.1 - 7.1e-08 32.5 0.1 0.00026 21.0 0.0 2.8 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_lid_3 PF17862.1 OQR95602.1 - 2.4e-06 27.2 0.1 5.4e-06 26.1 0.1 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 OQR95602.1 - 5.2e-06 27.0 0.0 0.13 12.7 0.0 3.6 2 1 1 3 3 3 1 AAA ATPase domain TsaE PF02367.17 OQR95602.1 - 3.5e-05 23.8 0.0 0.21 11.6 0.0 2.4 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_18 PF13238.6 OQR95602.1 - 0.0001 22.9 0.1 0.19 12.3 0.0 2.9 3 0 0 3 3 2 1 AAA domain RNA_helicase PF00910.22 OQR95602.1 - 0.00037 20.8 0.1 0.12 12.8 0.1 3.3 2 1 0 2 2 2 1 RNA helicase AAA_22 PF13401.6 OQR95602.1 - 0.00038 20.8 0.2 0.085 13.1 0.1 3.4 2 1 1 3 3 3 1 AAA domain AAA_33 PF13671.6 OQR95602.1 - 0.0004 20.6 0.0 0.15 12.2 0.0 2.4 2 0 0 2 2 2 1 AAA domain RuvB_N PF05496.12 OQR95602.1 - 0.00046 20.0 0.2 0.023 14.4 0.0 2.5 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain Zeta_toxin PF06414.12 OQR95602.1 - 0.00064 19.1 0.0 0.24 10.6 0.0 2.4 2 0 0 2 2 2 1 Zeta toxin Mg_chelatase PF01078.21 OQR95602.1 - 0.0017 17.8 0.2 0.0091 15.4 0.0 2.0 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_14 PF13173.6 OQR95602.1 - 0.0019 18.2 0.0 0.018 15.1 0.0 2.3 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 OQR95602.1 - 0.0022 17.9 0.2 0.31 10.9 0.0 2.7 2 0 0 2 2 2 1 NACHT domain AAA_25 PF13481.6 OQR95602.1 - 0.006 16.2 0.5 0.099 12.2 0.6 2.3 1 1 1 2 2 2 1 AAA domain TIP49 PF06068.13 OQR95602.1 - 0.007 15.6 0.3 0.032 13.4 0.1 1.9 2 0 0 2 2 2 1 TIP49 P-loop domain IstB_IS21 PF01695.17 OQR95602.1 - 0.0084 15.9 0.1 0.034 13.9 0.0 2.0 2 0 0 2 2 2 1 IstB-like ATP binding protein DUF815 PF05673.13 OQR95602.1 - 0.0099 15.1 0.0 3.2 6.9 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_7 PF12775.7 OQR95602.1 - 0.01 15.4 0.3 1.8 8.1 0.1 2.6 2 1 0 2 2 2 1 P-loop containing dynein motor region AAA_24 PF13479.6 OQR95602.1 - 0.011 15.5 0.0 0.048 13.4 0.0 2.1 3 0 0 3 3 2 0 AAA domain AAA_3 PF07726.11 OQR95602.1 - 0.013 15.4 0.1 0.45 10.4 0.0 2.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.14 OQR95602.1 - 0.021 15.0 0.0 0.11 12.7 0.0 2.0 2 0 0 2 2 2 0 AAA domain (Cdc48 subfamily) AAA_17 PF13207.6 OQR95602.1 - 0.032 14.6 0.1 0.49 10.8 0.0 2.6 3 0 0 3 3 2 0 AAA domain Sigma54_activat PF00158.26 OQR95602.1 - 0.042 13.6 0.1 7.5 6.2 0.0 3.0 3 0 0 3 3 3 0 Sigma-54 interaction domain AAA_30 PF13604.6 OQR95602.1 - 0.065 13.0 0.0 0.67 9.6 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_11 PF13086.6 OQR95602.1 - 0.15 11.8 0.0 6.1 6.6 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 OQR95602.1 - 0.19 11.9 0.0 1.1 9.5 0.0 2.2 2 0 0 2 2 2 0 AAA domain PhoH PF02562.16 OQR95602.1 - 0.21 11.0 0.3 0.6 9.5 0.3 1.7 1 0 0 1 1 1 0 PhoH-like protein AAA_19 PF13245.6 OQR95602.1 - 0.24 11.7 0.7 7.4 6.9 0.3 3.0 2 1 1 3 3 3 0 AAA domain Cons_hypoth698 PF03601.14 OQR95603.1 - 0.0041 16.1 0.1 0.0064 15.4 0.1 1.3 1 0 0 1 1 1 1 Conserved hypothetical protein 698 LRR_8 PF13855.6 OQR95605.1 - 2e-18 65.9 35.7 1.7e-08 34.1 4.5 6.4 3 2 1 6 6 6 4 Leucine rich repeat LRR_4 PF12799.7 OQR95605.1 - 2.5e-18 65.9 43.5 0.0014 18.9 0.1 8.3 3 1 7 10 10 10 10 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 OQR95605.1 - 0.77 10.5 31.4 19 6.3 1.0 7.8 6 3 0 6 6 6 0 Leucine Rich Repeat Globin PF00042.22 OQR95606.1 - 0.00011 22.7 6.0 2.7 8.6 0.2 4.8 3 2 0 3 3 3 3 Globin Aa_trans PF01490.18 OQR95609.1 - 1.4e-24 86.6 30.5 3.5e-10 39.2 9.9 3.2 3 0 0 3 3 3 3 Transmembrane amino acid transporter protein Pkinase PF00069.25 OQR95612.1 - 4.6e-56 190.1 0.0 1.4e-55 188.5 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQR95612.1 - 1e-28 100.4 0.0 1.6e-28 99.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 OQR95612.1 - 6.1e-05 22.5 0.1 0.00011 21.6 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 OQR95612.1 - 0.0041 16.5 0.0 0.0089 15.4 0.0 1.5 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 OQR95612.1 - 0.018 15.0 0.2 0.15 12.0 0.1 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family FTA2 PF13095.6 OQR95612.1 - 0.026 14.2 0.0 0.069 12.8 0.0 1.7 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Pkinase_fungal PF17667.1 OQR95612.1 - 0.16 10.7 0.0 0.25 10.0 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase FYVE_2 PF02318.16 OQR95613.1 - 0.0045 17.2 9.7 0.011 16.0 9.7 1.6 1 0 0 1 1 1 1 FYVE-type zinc finger DZR PF12773.7 OQR95613.1 - 0.041 13.9 1.3 0.041 13.9 1.3 2.8 2 0 0 2 2 2 0 Double zinc ribbon FYVE PF01363.21 OQR95613.1 - 1 9.5 23.1 6 7.1 23.1 2.2 1 1 0 1 1 1 0 FYVE zinc finger IQ PF00612.27 OQR95615.1 - 0.012 15.4 22.2 0.02 14.6 1.4 4.2 2 1 1 3 3 3 0 IQ calmodulin-binding motif LRR_6 PF13516.6 OQR95616.1 - 0.0036 17.2 10.2 6.9 7.0 0.1 4.8 5 0 0 5 5 5 3 Leucine Rich repeat XendoU PF09412.10 OQR95616.1 - 0.4 9.9 5.4 0.094 11.9 1.2 2.0 3 0 0 3 3 3 0 Endoribonuclease XendoU LRR_4 PF12799.7 OQR95616.1 - 1.1 9.8 4.5 0.88 10.1 0.4 2.8 2 1 1 3 3 3 0 Leucine Rich repeats (2 copies) DUF2048 PF09752.9 OQR95616.1 - 1.7 7.6 7.2 0.32 10.1 3.6 1.5 2 0 0 2 2 2 0 Abhydrolase domain containing 18 AAA_28 PF13521.6 OQR95617.1 - 1.9e-13 51.0 0.0 4.2e-13 49.9 0.0 1.5 2 0 0 2 2 2 1 AAA domain EF-hand_1 PF00036.32 OQR95620.1 - 3.9e-35 116.8 18.9 2.7e-09 35.9 0.1 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 OQR95620.1 - 1.6e-30 105.4 11.4 2.7e-16 59.8 0.7 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 OQR95620.1 - 3.4e-27 92.0 10.9 1.3e-09 37.1 0.1 4.4 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 OQR95620.1 - 8.3e-26 89.6 15.5 3.2e-12 46.1 1.1 3.7 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.6 OQR95620.1 - 2.1e-18 64.9 17.7 4.8e-06 25.8 0.2 4.5 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.6 OQR95620.1 - 5e-15 55.6 0.4 2.8e-07 30.8 0.1 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 OQR95620.1 - 1.1e-06 28.6 7.7 0.11 12.5 0.8 3.3 1 1 2 3 3 3 3 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 OQR95620.1 - 7.3e-05 23.1 2.1 0.062 13.6 0.1 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region Dockerin_1 PF00404.18 OQR95620.1 - 0.00031 20.9 0.1 0.39 10.9 0.1 2.4 2 0 0 2 2 2 2 Dockerin type I domain SurA_N_3 PF13624.6 OQR95620.1 - 0.00031 20.6 2.2 0.2 11.5 0.2 2.2 1 1 0 2 2 2 2 SurA N-terminal domain EF-hand_14 PF17959.1 OQR95620.1 - 0.00041 20.6 1.7 0.25 11.7 0.2 2.6 1 1 1 2 2 2 2 EF-hand domain SurA_N_2 PF13623.6 OQR95620.1 - 0.0098 15.8 3.4 1.2 9.0 0.4 2.8 1 1 1 2 2 2 2 SurA N-terminal domain PMBR PF09373.10 OQR95620.1 - 0.013 15.6 1.1 43 4.5 0.0 4.7 5 0 0 5 5 5 0 Pseudomurein-binding repeat DUF4601 PF15373.6 OQR95620.1 - 0.02 13.9 0.1 0.04 12.9 0.0 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4601) Caleosin PF05042.13 OQR95620.1 - 0.023 14.6 1.6 7.7 6.4 0.0 3.5 1 1 3 4 4 4 0 Caleosin related protein DUF853 PF05872.12 OQR95620.1 - 0.024 13.3 0.2 0.44 9.1 0.0 2.0 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF853) SUB1_ProdP9 PF18213.1 OQR95620.1 - 0.028 14.2 2.7 0.032 14.1 0.2 2.0 1 1 1 2 2 2 0 SUB1 protease Prodomain ProdP9 EF-hand_11 PF08976.11 OQR95620.1 - 0.066 14.1 0.4 12 6.8 0.0 2.1 1 1 1 2 2 2 0 EF-hand domain LETM1 PF07766.13 OQR95620.1 - 0.09 12.1 3.2 0.13 11.6 1.1 2.1 1 1 0 1 1 1 0 LETM1-like protein DUF3008 PF11450.8 OQR95620.1 - 0.12 12.5 0.1 0.12 12.5 0.1 2.6 3 0 0 3 3 2 0 Protein of unknwon function (DUF3008) DUF21 PF01595.20 OQR95620.1 - 0.23 11.1 0.6 0.65 9.7 0.2 1.9 2 0 0 2 2 2 0 Cyclin M transmembrane N-terminal domain Phg_2220_C PF09524.10 OQR95620.1 - 0.39 10.8 3.0 4.9 7.3 0.1 2.7 2 1 1 3 3 3 0 Conserved phage C-terminus (Phg_2220_C) Peptidase_C1 PF00112.23 OQR95621.1 - 6.6e-52 176.7 5.6 9.9e-52 176.2 5.6 1.2 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 OQR95621.1 - 7.7e-05 23.1 0.0 0.00015 22.1 0.0 1.6 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.15 OQR95621.1 - 0.00028 19.8 0.8 0.044 12.6 0.4 2.3 2 0 0 2 2 2 2 Peptidase C1-like family Dict-STAT-coil PF09267.10 OQR95621.1 - 0.00034 21.0 0.0 0.00069 20.0 0.0 1.4 1 0 0 1 1 1 1 Dictyostelium STAT, coiled coil WD40 PF00400.32 OQR95622.1 - 7e-42 140.6 22.8 6.7e-09 36.2 0.1 7.6 8 0 0 8 8 8 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OQR95622.1 - 2.6e-18 66.1 6.3 0.00027 21.2 0.2 6.2 1 1 4 6 6 6 6 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 OQR95622.1 - 5.8e-10 39.4 2.4 0.01 15.7 0.2 3.2 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A zf-CCHC_2 PF13696.6 OQR95622.1 - 1e-08 34.9 3.4 2.7e-08 33.5 3.4 1.8 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.23 OQR95622.1 - 0.003 17.6 2.5 0.011 15.8 2.5 2.0 1 0 0 1 1 1 1 Zinc knuckle Nucleoporin_N PF08801.11 OQR95622.1 - 0.0032 16.3 0.3 2.2 7.0 0.0 2.3 1 1 0 2 2 2 2 Nup133 N terminal like zf-CCHC_5 PF14787.6 OQR95622.1 - 0.033 13.9 0.6 0.08 12.7 0.6 1.6 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger Anoctamin PF04547.12 OQR95623.1 - 2.1e-21 76.3 5.6 2.4e-13 49.7 1.1 3.0 1 1 1 2 2 2 2 Calcium-activated chloride channel Anoct_dimer PF16178.5 OQR95624.1 - 3.8e-10 39.9 0.2 5.3e-10 39.4 0.2 1.1 1 0 0 1 1 1 1 Dimerisation domain of Ca+-activated chloride-channel, anoctamin RRXRR PF14239.6 OQR95624.1 - 0.069 13.0 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 RRXRR protein Anoctamin PF04547.12 OQR95625.1 - 1.7e-130 435.8 47.7 1.7e-106 356.8 22.0 3.1 3 0 0 3 3 3 3 Calcium-activated chloride channel Anoct_dimer PF16178.5 OQR95625.1 - 1.2e-07 31.7 0.1 3.2e-07 30.3 0.1 1.6 2 0 0 2 2 2 1 Dimerisation domain of Ca+-activated chloride-channel, anoctamin Anoctamin PF04547.12 OQR95626.1 - 8.6e-90 301.7 5.1 1.1e-89 301.4 5.1 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel 3Beta_HSD PF01073.19 OQR95626.1 - 1.6e-39 135.6 0.0 2.9e-39 134.8 0.0 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 OQR95626.1 - 3.8e-23 82.2 0.0 6.1e-23 81.5 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 OQR95626.1 - 1e-13 51.6 0.0 2.1e-13 50.6 0.0 1.5 1 0 0 1 1 1 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 OQR95626.1 - 4.2e-13 49.4 0.0 9.3e-12 45.0 0.0 2.2 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 OQR95626.1 - 5.3e-11 42.2 0.0 6.2e-07 28.8 0.0 2.2 2 0 0 2 2 2 2 Male sterility protein Polysacc_synt_2 PF02719.15 OQR95626.1 - 8.6e-09 34.9 0.0 1.6e-08 34.1 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 OQR95626.1 - 1.7e-07 30.6 0.0 2.6e-07 30.0 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain adh_short PF00106.25 OQR95626.1 - 0.0014 18.1 0.0 0.0025 17.3 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase NmrA PF05368.13 OQR95626.1 - 0.0033 17.0 0.0 0.006 16.2 0.0 1.4 1 0 0 1 1 1 1 NmrA-like family KR PF08659.10 OQR95626.1 - 0.0057 16.6 0.0 0.027 14.4 0.1 2.0 2 1 0 2 2 2 1 KR domain TrkA_N PF02254.18 OQR95626.1 - 0.0081 16.4 0.0 0.015 15.5 0.0 1.4 1 0 0 1 1 1 1 TrkA-N domain SUB1_ProdP9 PF18213.1 OQR95626.1 - 0.078 12.8 0.0 0.17 11.7 0.0 1.6 1 0 0 1 1 1 0 SUB1 protease Prodomain ProdP9 MT-A70 PF05063.14 OQR95628.1 - 1.8e-17 63.8 1.0 1.8e-17 63.8 1.0 1.6 2 0 0 2 2 2 1 MT-A70 Torus PF16131.5 OQR95628.1 - 0.091 13.5 3.8 2 9.1 0.3 2.2 1 1 1 2 2 2 0 Torus domain MT-A70 PF05063.14 OQR95629.1 - 1.3e-21 77.3 0.0 1.4e-21 77.2 0.0 1.0 1 0 0 1 1 1 1 MT-A70 Ricin_B_lectin PF00652.22 OQR95630.1 - 1.3e-12 48.1 0.9 2.8e-12 47.0 0.9 1.6 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.6 OQR95630.1 - 0.022 15.5 1.8 0.69 10.7 1.1 3.0 1 1 1 2 2 2 0 Ricin-type beta-trefoil lectin domain-like TFIIA PF03153.13 OQR95630.1 - 8.2 6.3 9.6 11 5.9 9.6 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PAP_assoc PF03828.19 OQR95631.1 - 2.5e-14 53.2 0.1 8.2e-14 51.6 0.1 2.0 1 1 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 OQR95631.1 - 0.0015 18.8 0.0 0.0026 18.0 0.0 1.4 1 0 0 1 1 1 1 Nucleotidyltransferase domain Polbeta PF18765.1 OQR95631.1 - 0.0098 16.0 0.0 0.019 15.1 0.0 1.4 1 0 0 1 1 1 1 Polymerase beta, Nucleotidyltransferase EF-hand_1 PF00036.32 OQR95632.1 - 5.5e-10 38.1 0.6 0.00037 19.8 0.0 2.6 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 OQR95632.1 - 9.4e-10 37.6 0.5 0.00086 19.1 0.0 2.8 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.6 OQR95632.1 - 1.8e-08 34.7 0.3 4.4e-08 33.5 0.3 1.7 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.6 OQR95632.1 - 1.9e-08 33.4 2.8 9.4e-05 21.7 0.0 2.7 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 OQR95632.1 - 1.9e-06 27.6 1.5 0.032 14.1 0.0 2.8 1 1 1 2 2 2 2 EF-hand domain pair RNA_pol_Rpb2_6 PF00562.28 OQR95634.1 - 1.1e-124 416.5 0.1 1.5e-124 416.1 0.1 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 OQR95634.1 - 6.4e-67 225.0 0.1 9.1e-67 224.5 0.1 1.2 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.14 OQR95634.1 - 8.9e-52 175.5 0.0 1.6e-51 174.7 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.20 OQR95634.1 - 1.1e-32 112.3 0.1 4.1e-32 110.4 0.1 2.1 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_3 PF04565.16 OQR95634.1 - 2.9e-26 91.4 0.0 6.3e-26 90.3 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_4 PF04566.13 OQR95634.1 - 1e-24 86.6 0.7 1e-24 86.6 0.7 2.0 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_5 PF04567.17 OQR95634.1 - 7.4e-16 58.5 2.2 2.1e-15 57.0 2.2 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 NTF2 PF02136.20 OQR95636.1 - 2.8e-20 73.1 0.4 6.3e-20 71.9 0.1 1.7 2 0 0 2 2 2 1 Nuclear transport factor 2 (NTF2) domain ISG65-75 PF11727.8 OQR95636.1 - 0.0002 20.7 1.7 0.00029 20.2 1.7 1.2 1 0 0 1 1 1 1 Invariant surface glycoprotein DIT1_PvcA PF05141.12 OQR95636.1 - 0.074 12.5 1.9 0.1 12.0 1.9 1.2 1 0 0 1 1 1 0 Pyoverdine/dityrosine biosynthesis protein DUF4440 PF14534.6 OQR95636.1 - 0.11 12.9 0.0 0.23 11.9 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4440) DUF4407 PF14362.6 OQR95636.1 - 0.12 11.6 3.9 0.18 11.1 3.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Fib_alpha PF08702.10 OQR95636.1 - 0.13 12.4 4.1 0.11 12.6 2.2 1.9 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family CENP-H PF05837.12 OQR95636.1 - 0.33 11.4 7.8 0.14 12.6 5.4 1.7 2 0 0 2 2 2 0 Centromere protein H (CENP-H) Erf4 PF10256.9 OQR95637.1 - 4.1e-07 30.1 0.0 5.5e-07 29.7 0.0 1.1 1 0 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family ETC_C1_NDUFA5 PF04716.14 OQR95638.1 - 4.5e-19 68.0 0.0 6.3e-19 67.5 0.0 1.2 1 0 0 1 1 1 1 ETC complex I subunit conserved region TRAPPC9-Trs120 PF08626.11 OQR95638.1 - 0.00074 17.0 0.0 0.00082 16.9 0.0 1.0 1 0 0 1 1 1 1 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit FATC PF02260.20 OQR95638.1 - 0.14 12.0 0.1 0.34 10.8 0.1 1.6 1 0 0 1 1 1 0 FATC domain TFIIB PF00382.19 OQR95639.1 - 1.9e-18 66.3 0.5 1.3e-11 44.4 0.2 2.5 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.12 OQR95639.1 - 4.3e-11 42.2 4.0 1.1e-10 40.8 0.6 2.4 2 0 0 2 2 2 1 TFIIB zinc-binding Ribosomal_S27e PF01667.17 OQR95639.1 - 0.028 14.1 0.5 0.67 9.7 0.1 2.3 2 0 0 2 2 2 0 Ribosomal protein S27 Cyclin_C PF02984.19 OQR95639.1 - 0.091 12.8 0.0 9.6 6.3 0.0 2.4 1 1 1 2 2 2 0 Cyclin, C-terminal domain A2L_zn_ribbon PF08792.10 OQR95639.1 - 0.12 12.2 2.4 2.9 7.7 0.6 2.4 2 0 0 2 2 2 0 A2L zinc ribbon domain HTH_49 PF18010.1 OQR95639.1 - 0.15 12.0 0.0 0.33 10.9 0.0 1.5 1 0 0 1 1 1 0 Cry35Ab1 HTH C-terminal domain zf-ribbon_3 PF13248.6 OQR95639.1 - 9.2 5.8 6.5 21 4.7 0.1 3.3 3 0 0 3 3 3 0 zinc-ribbon domain Sas10 PF09368.10 OQR95640.1 - 4.1e-24 84.9 10.7 4.1e-24 84.9 10.7 2.9 4 0 0 4 4 4 1 Sas10 C-terminal domain Sas10_Utp3 PF04000.15 OQR95640.1 - 2.6e-11 44.0 1.5 3.4e-10 40.4 0.5 3.1 2 1 0 2 2 2 1 Sas10/Utp3/C1D family Kinesin PF00225.23 OQR95641.1 - 5.7e-85 285.2 0.1 5.7e-85 285.2 0.1 1.5 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 OQR95641.1 - 3.2e-20 72.6 0.0 8.2e-20 71.3 0.0 1.7 1 0 0 1 1 1 1 Microtubule binding AIG2_2 PF13772.6 OQR95641.1 - 2.2e-14 53.6 0.3 2.6e-06 27.7 0.0 2.6 2 0 0 2 2 2 2 AIG2-like family GGACT PF06094.12 OQR95641.1 - 1.2e-13 51.7 0.0 1.3e-05 25.7 0.0 2.8 2 0 0 2 2 2 2 Gamma-glutamyl cyclotransferase, AIG2-like Cast PF10174.9 OQR95641.1 - 0.00024 19.5 4.5 0.00038 18.9 4.5 1.1 1 0 0 1 1 1 1 RIM-binding protein of the cytomatrix active zone HMMR_N PF15905.5 OQR95641.1 - 0.085 12.3 6.6 0.15 11.6 6.6 1.2 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal Spc7 PF08317.11 OQR95641.1 - 0.14 11.0 8.1 0.25 10.2 8.1 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein SOGA PF11365.8 OQR95641.1 - 0.31 12.2 4.6 4.4 8.5 0.1 2.7 2 0 0 2 2 2 0 Protein SOGA Tropomyosin PF00261.20 OQR95641.1 - 0.33 10.3 5.9 0.54 9.6 5.9 1.2 1 0 0 1 1 1 0 Tropomyosin FliD_N PF02465.18 OQR95641.1 - 1.1 10.0 7.5 82 4.0 6.1 3.5 2 1 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus UPF0242 PF06785.11 OQR95641.1 - 1.9 8.5 7.8 3.4 7.7 7.8 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Sec8_exocyst PF04048.14 OQR95641.1 - 3.4 7.6 8.0 12 5.7 0.0 3.5 3 0 0 3 3 3 0 Sec8 exocyst complex component specific domain zf-HC5HC2H_2 PF13832.6 OQR95642.1 - 2.6e-32 111.3 77.2 7.1e-16 58.3 12.1 8.8 7 2 3 10 10 10 4 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 OQR95642.1 - 1.9e-21 76.1 28.5 1.1e-13 51.2 7.4 9.6 5 3 3 9 9 9 3 PHD-like zinc-binding domain PHD PF00628.29 OQR95642.1 - 6.5e-16 58.0 95.2 7.5e-09 35.4 4.1 8.5 7 1 1 8 8 8 5 PHD-finger PHD_2 PF13831.6 OQR95642.1 - 2.7e-13 49.2 1.3 2.7e-13 49.2 1.3 7.1 7 1 0 7 7 7 3 PHD-finger C1_1 PF00130.22 OQR95642.1 - 0.0024 17.7 0.7 0.0024 17.7 0.7 8.6 9 2 2 11 11 11 4 Phorbol esters/diacylglycerol binding domain (C1 domain) Cullin_binding PF03556.15 OQR95643.1 - 1.4e-33 115.9 3.7 7e-33 113.6 2.0 2.1 2 0 0 2 2 2 1 Cullin binding SAP PF02037.27 OQR95643.1 - 1.4e-12 47.0 1.3 1.4e-12 47.0 1.3 1.8 2 0 0 2 2 2 1 SAP domain Rho_N PF07498.12 OQR95643.1 - 0.003 17.5 0.7 0.0081 16.1 0.7 1.8 1 0 0 1 1 1 1 Rho termination factor, N-terminal domain DUF573 PF04504.14 OQR95643.1 - 0.16 12.6 2.9 0.72 10.6 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function, DUF573 Xpo1 PF08389.12 OQR95644.1 - 1.3e-29 103.2 6.9 9.1e-29 100.4 0.8 4.0 4 0 0 4 4 4 2 Exportin 1-like protein AAA_8 PF12780.7 OQR95645.1 - 2.4e-82 276.2 0.0 5.9e-82 274.9 0.0 1.7 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 AAA_6 PF12774.7 OQR95645.1 - 8.5e-79 264.9 0.0 5.7e-74 249.0 0.0 3.6 3 0 0 3 3 3 2 Hydrolytic ATP binding site of dynein motor region Dynein_C PF18199.1 OQR95645.1 - 2.6e-77 260.1 0.1 6.5e-77 258.8 0.1 1.7 1 0 0 1 1 1 1 Dynein heavy chain C-terminal domain AAA_9 PF12781.7 OQR95645.1 - 1.3e-74 250.0 2.0 2e-74 249.4 0.2 2.2 2 0 0 2 2 2 1 ATP-binding dynein motor region MT PF12777.7 OQR95645.1 - 4.6e-71 239.6 10.5 7.7e-71 238.9 10.5 1.4 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_7 PF12775.7 OQR95645.1 - 1.4e-58 197.4 0.5 2.6e-55 186.7 0.1 3.1 3 0 0 3 3 2 2 P-loop containing dynein motor region AAA_lid_11 PF18198.1 OQR95645.1 - 1.1e-45 155.4 0.0 2.9e-44 150.8 0.0 2.5 2 0 0 2 2 2 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 OQR95645.1 - 1.1e-34 119.1 0.2 9.1e-33 112.9 0.0 3.6 3 0 0 3 3 3 1 Dynein heavy chain region D6 P-loop domain AAA_lid_1 PF17857.1 OQR95645.1 - 4.7e-24 84.5 0.1 2.1e-23 82.4 0.1 2.2 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 OQR95645.1 - 1.6e-19 70.3 0.0 4.3e-09 36.5 0.0 4.5 5 0 0 5 5 4 3 AAA domain (dynein-related subfamily) Dynein_AAA_lid PF17852.1 OQR95645.1 - 2e-17 63.5 0.1 7.3e-17 61.7 0.1 2.1 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_22 PF13401.6 OQR95645.1 - 5.7e-09 36.4 0.6 0.019 15.2 0.0 4.4 4 0 0 4 4 4 2 AAA domain AAA_16 PF13191.6 OQR95645.1 - 6.2e-07 29.9 0.1 0.027 14.9 0.0 3.9 4 0 0 4 4 3 2 AAA ATPase domain AAA_18 PF13238.6 OQR95645.1 - 3.3e-05 24.4 0.6 0.33 11.5 0.0 4.9 4 0 0 4 4 4 1 AAA domain TrwB_AAD_bind PF10412.9 OQR95645.1 - 0.0014 17.6 0.2 1.5 7.7 0.1 2.6 2 0 0 2 2 2 2 Type IV secretion-system coupling protein DNA-binding domain AAA_30 PF13604.6 OQR95645.1 - 0.0031 17.3 3.0 0.74 9.5 0.0 3.0 3 0 0 3 3 3 2 AAA domain ATP_bind_1 PF03029.17 OQR95645.1 - 0.0078 16.0 2.1 0.056 13.2 0.0 3.2 3 0 0 3 3 3 1 Conserved hypothetical ATP binding protein AAA_19 PF13245.6 OQR95645.1 - 0.017 15.5 5.9 0.33 11.3 0.0 3.4 4 0 0 4 4 2 0 AAA domain AAA PF00004.29 OQR95645.1 - 0.025 15.0 0.1 0.52 10.7 0.0 3.0 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.17 OQR95645.1 - 0.025 14.3 0.1 5.9 6.6 0.0 2.8 2 0 0 2 2 2 0 IstB-like ATP binding protein ABC_tran PF00005.27 OQR95645.1 - 0.029 14.9 0.0 22 5.6 0.0 3.2 2 0 0 2 2 2 0 ABC transporter AAA_11 PF13086.6 OQR95645.1 - 0.037 13.8 0.0 0.037 13.8 0.0 3.1 3 0 0 3 3 3 0 AAA domain PhoH PF02562.16 OQR95645.1 - 0.044 13.2 0.4 9.3 5.6 0.0 3.0 3 0 0 3 3 3 0 PhoH-like protein Mg_chelatase PF01078.21 OQR95645.1 - 0.076 12.4 1.0 3.5 7.0 0.1 3.2 3 1 0 3 3 3 0 Magnesium chelatase, subunit ChlI Sigma54_activ_2 PF14532.6 OQR95645.1 - 0.13 12.4 0.9 3 8.0 0.0 3.3 3 0 0 3 3 2 0 Sigma-54 interaction domain DUF737 PF05300.11 OQR95645.1 - 0.36 11.2 10.3 0.022 15.1 2.5 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF737) RNA_helicase PF00910.22 OQR95645.1 - 0.47 10.9 4.2 7.7 7.0 0.1 3.7 3 0 0 3 3 3 0 RNA helicase FtsK_SpoIIIE PF01580.18 OQR95645.1 - 2.1 7.7 4.8 0.63 9.3 0.0 2.6 4 0 0 4 4 2 0 FtsK/SpoIIIE family DUF16 PF01519.16 OQR95645.1 - 5 7.7 8.0 2.9 8.4 0.3 2.9 2 0 0 2 2 2 0 Protein of unknown function DUF16 GrpE PF01025.19 OQR95645.1 - 8.4 6.0 13.7 0.059 13.0 2.3 2.8 2 0 0 2 2 1 0 GrpE HgmA PF04209.13 OQR95646.1 - 1.7e-209 695.8 1.9 2e-209 695.6 1.9 1.0 1 0 0 1 1 1 1 homogentisate 1,2-dioxygenase PhyH PF05721.13 OQR95648.1 - 5.9e-49 167.2 0.0 7.2e-49 166.9 0.0 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) GST_N_2 PF13409.6 OQR95650.1 - 2e-25 88.9 0.1 1.1e-23 83.3 0.0 2.4 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 OQR95650.1 - 5.2e-13 48.8 0.1 1.9e-12 47.0 0.0 1.9 3 0 0 3 3 3 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 OQR95650.1 - 1e-09 38.5 0.0 1.7e-09 37.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 OQR95650.1 - 7.4e-08 32.5 0.0 1.5e-07 31.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_6 PF17171.4 OQR95650.1 - 0.00016 21.4 0.1 0.00028 20.6 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 OQR95650.1 - 0.00091 19.6 0.0 0.038 14.4 0.0 2.8 2 1 0 2 2 2 1 Glutathione S-transferase, N-terminal domain TBCC PF07986.12 OQR95651.1 - 5.1e-36 123.0 0.4 7.8e-36 122.4 0.4 1.3 1 0 0 1 1 1 1 Tubulin binding cofactor C CAP_GLY PF01302.25 OQR95651.1 - 8.9e-23 80.1 0.2 1.4e-22 79.5 0.2 1.3 1 0 0 1 1 1 1 CAP-Gly domain TBCC_N PF16752.5 OQR95651.1 - 4.8e-19 68.9 1.9 7.8e-19 68.2 1.9 1.3 1 0 0 1 1 1 1 Tubulin-specific chaperone C N-terminal domain Nitroreductase PF00881.24 OQR95652.1 - 1.5e-22 80.5 0.0 3.6e-10 40.2 0.0 2.3 2 0 0 2 2 2 2 Nitroreductase family RPA43_OB PF17875.1 OQR95652.1 - 1.6e-10 41.7 3.7 1.9e-05 25.3 0.0 3.2 2 1 1 3 3 3 2 RPA43 OB domain in RNA Pol I SHS2_Rpb7-N PF03876.17 OQR95652.1 - 8.2e-08 32.5 0.0 1.9e-07 31.4 0.0 1.6 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 Uds1 PF15456.6 OQR95653.1 - 0.0053 16.9 8.0 0.0062 16.7 8.0 1.2 1 0 0 1 1 1 1 Up-regulated During Septation TMPIT PF07851.13 OQR95653.1 - 2.9 7.0 4.9 3.1 7.0 4.9 1.1 1 0 0 1 1 1 0 TMPIT-like protein eIF-5_eIF-2B PF01873.17 OQR95654.1 - 3.6e-38 130.0 0.1 5.2e-38 129.5 0.1 1.2 1 0 0 1 1 1 1 Domain found in IF2B/IF5 Lar_restr_allev PF14354.6 OQR95654.1 - 0.088 13.2 0.3 0.39 11.1 0.3 2.2 2 1 0 2 2 2 0 Restriction alleviation protein Lar Vps36-NZF-N PF16988.5 OQR95654.1 - 0.15 11.5 1.4 0.33 10.4 0.0 2.1 2 0 0 2 2 2 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain FAD_binding_3 PF01494.19 OQR95655.1 - 1.7e-21 76.8 0.0 1.7e-10 40.7 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain SE PF08491.10 OQR95655.1 - 6e-05 22.2 0.0 0.00013 21.1 0.0 1.5 2 0 0 2 2 2 1 Squalene epoxidase DAO PF01266.24 OQR95655.1 - 0.00016 21.4 0.0 0.00065 19.4 0.0 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 OQR95655.1 - 0.0015 18.7 0.0 0.0034 17.6 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.14 OQR95655.1 - 0.0018 17.2 0.0 4.4 6.0 0.0 3.0 3 0 0 3 3 3 2 Tryptophan halogenase TrkA_N PF02254.18 OQR95655.1 - 0.0018 18.5 0.0 0.0055 17.0 0.0 1.8 2 0 0 2 2 2 1 TrkA-N domain Pyr_redox_2 PF07992.14 OQR95655.1 - 0.0063 15.8 0.0 0.052 12.8 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 OQR95655.1 - 0.056 12.5 0.8 3.5 6.6 0.4 2.5 2 1 0 2 2 2 0 Lycopene cyclase protein Pyr_redox PF00070.27 OQR95655.1 - 0.078 13.5 0.0 0.21 12.1 0.0 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase BT1 PF03092.16 OQR95656.1 - 4.6e-16 58.2 10.6 7e-14 50.9 0.8 2.7 2 1 1 3 3 3 2 BT1 family SRP14 PF02290.15 OQR95656.1 - 2.1e-06 28.0 0.1 4.2e-06 27.0 0.1 1.5 1 0 0 1 1 1 1 Signal recognition particle 14kD protein MFS_1_like PF12832.7 OQR95656.1 - 2.9e-05 23.1 18.5 9.9e-05 21.4 12.5 2.9 3 0 0 3 3 3 2 MFS_1 like family DUF4184 PF13803.6 OQR95656.1 - 0.96 9.1 9.6 7.6 6.2 0.1 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4184) DUF2085 PF09858.9 OQR95656.1 - 1.3 9.6 8.5 0.36 11.3 1.1 3.4 3 1 0 3 3 3 0 Predicted membrane protein (DUF2085) AAA PF00004.29 OQR95657.1 - 0.0062 17.0 0.3 0.05 14.0 0.3 2.6 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Herpes_Helicase PF02689.14 OQR95657.1 - 0.029 12.3 0.0 0.057 11.3 0.0 1.4 1 0 0 1 1 1 0 Helicase AAA_22 PF13401.6 OQR95657.1 - 0.037 14.3 0.0 0.11 12.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain zf-B_box PF00643.24 OQR95658.1 - 1.6e-14 53.8 20.1 3.3e-08 33.6 8.2 2.5 2 0 0 2 2 2 2 B-box zinc finger zf_CCCH_4 PF18345.1 OQR95658.1 - 3.1e-11 42.9 13.0 1.9e-05 24.5 6.0 2.4 2 0 0 2 2 2 2 Zinc finger domain R3H PF01424.22 OQR95658.1 - 1.1e-10 41.3 0.1 1.1e-10 41.3 0.1 2.2 3 0 0 3 3 2 1 R3H domain zf-CCCH_4 PF18044.1 OQR95658.1 - 1.9e-10 40.3 9.8 1.9e-05 24.3 4.0 2.4 2 0 0 2 2 2 2 CCCH-type zinc finger RRM_1 PF00076.22 OQR95658.1 - 3.9e-10 39.4 0.1 1e-09 38.1 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCCH PF00642.24 OQR95658.1 - 2.9e-09 36.6 8.2 0.00036 20.4 4.8 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 OQR95658.1 - 4.4e-08 33.8 5.1 0.0023 18.6 1.2 2.8 1 1 1 2 2 2 2 Torus domain zf-CCCH_2 PF14608.6 OQR95658.1 - 0.0031 17.9 9.6 0.33 11.5 0.6 2.5 2 0 0 2 2 2 2 RNA-binding, Nab2-type zinc finger zf-HIT PF04438.16 OQR95658.1 - 0.016 15.0 16.8 0.7 9.8 6.3 2.8 2 0 0 2 2 2 0 HIT zinc finger IBR PF01485.21 OQR95658.1 - 0.092 13.0 24.8 1.2 9.5 8.1 2.7 1 1 1 2 2 2 0 IBR domain, a half RING-finger domain zf-C2H2_11 PF16622.5 OQR95658.1 - 0.14 11.9 3.7 0.12 12.2 0.3 2.7 3 0 0 3 3 3 0 zinc-finger C2H2-type C1_4 PF07975.12 OQR95658.1 - 0.3 11.3 19.6 0.31 11.3 5.8 2.9 1 1 1 2 2 2 0 TFIIH C1-like domain zf-RanBP PF00641.18 OQR95659.1 - 3.1e-09 36.0 28.0 3.9e-05 22.9 4.2 3.4 3 0 0 3 3 3 3 Zn-finger in Ran binding protein and others DUF1677 PF07911.13 OQR95659.1 - 0.037 14.4 0.8 0.14 12.5 0.8 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1677) DZR PF12773.7 OQR95659.1 - 7.9 6.6 17.4 0.46 10.6 8.7 2.5 2 1 0 2 2 2 0 Double zinc ribbon ABA_GPCR PF12430.8 OQR95660.1 - 2.9e-31 108.6 10.7 2.9e-31 108.6 10.7 1.8 2 1 0 2 2 2 1 Abscisic acid G-protein coupled receptor GPHR_N PF12537.8 OQR95660.1 - 1.5e-22 79.5 0.0 3.9e-22 78.1 0.0 1.8 1 0 0 1 1 1 1 The Golgi pH Regulator (GPHR) Family N-terminal SAM_KSR1 PF13543.6 OQR95660.1 - 0.066 13.4 2.9 0.14 12.3 2.9 1.5 1 0 0 1 1 1 0 SAM like domain present in kinase suppressor RAS 1 PKS_DE PF18369.1 OQR95660.1 - 0.094 13.3 0.0 0.26 11.9 0.0 1.8 1 0 0 1 1 1 0 Polyketide synthase dimerisation element domain DUF4635 PF15466.6 OQR95660.1 - 0.64 9.5 5.8 0.38 10.3 2.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4635) THF_DHG_CYH_C PF02882.19 OQR95661.1 - 7.4e-63 210.6 1.0 1.3e-62 209.8 1.0 1.4 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.23 OQR95661.1 - 1.4e-32 112.4 0.3 4e-32 110.9 0.3 1.9 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain p25-alpha PF05517.12 OQR95661.1 - 7.8e-12 45.6 0.0 7.6e-08 32.7 0.0 2.8 2 0 0 2 2 2 2 p25-alpha CH PF00307.31 OQR95661.1 - 4.4e-05 23.6 0.0 0.0003 20.9 0.0 2.5 3 0 0 3 3 3 1 Calponin homology (CH) domain CAMSAP_CH PF11971.8 OQR95661.1 - 0.051 13.4 0.0 0.18 11.6 0.0 1.9 1 0 0 1 1 1 0 CAMSAP CH domain Spc29 PF17082.5 OQR95661.1 - 0.052 13.4 3.3 0.14 12.0 1.5 2.4 2 0 0 2 2 2 0 Spindle Pole Component 29 CH_2 PF06294.11 OQR95661.1 - 0.068 13.3 0.0 0.35 11.0 0.0 2.2 1 0 0 1 1 1 0 CH-like domain in sperm protein BST2 PF16716.5 OQR95661.1 - 0.19 12.4 2.2 0.56 10.8 2.2 1.8 1 0 0 1 1 1 0 Bone marrow stromal antigen 2 DUF1765 PF08578.10 OQR95661.1 - 1.9 8.9 4.7 2.1 8.8 1.9 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1765) Ribonuclease_T2 PF00445.18 OQR95662.1 - 1.6e-27 96.9 0.7 3.1e-27 96.0 0.8 1.3 1 1 0 1 1 1 1 Ribonuclease T2 family Ribonuclease_T2 PF00445.18 OQR95663.1 - 1.1e-25 91.0 0.0 1.5e-25 90.5 0.0 1.1 1 0 0 1 1 1 1 Ribonuclease T2 family Ribonuclease_T2 PF00445.18 OQR95664.1 - 1.1e-25 90.9 0.0 1.6e-25 90.4 0.0 1.2 1 0 0 1 1 1 1 Ribonuclease T2 family DUF1270 PF06900.11 OQR95664.1 - 0.23 11.9 2.3 0.41 11.1 0.6 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1270) NARP1 PF12569.8 OQR95665.1 - 1e-157 526.2 17.0 1e-157 526.2 17.0 4.0 3 1 0 4 4 4 1 NMDA receptor-regulated protein 1 TPR_2 PF07719.17 OQR95665.1 - 2.9e-29 98.8 27.2 5.3e-07 29.3 0.1 12.7 13 0 0 13 13 13 6 Tetratricopeptide repeat TPR_8 PF13181.6 OQR95665.1 - 1.3e-26 90.5 20.0 1.1e-05 25.3 0.0 11.0 10 0 0 10 10 10 5 Tetratricopeptide repeat TPR_1 PF00515.28 OQR95665.1 - 4e-20 70.7 35.5 2.2e-06 27.2 0.2 10.7 13 0 0 13 13 12 5 Tetratricopeptide repeat TPR_11 PF13414.6 OQR95665.1 - 3.9e-19 68.1 24.3 4.3e-07 29.5 0.5 8.5 6 1 2 8 8 8 4 TPR repeat TPR_12 PF13424.6 OQR95665.1 - 1.4e-17 63.7 25.8 8.3e-07 29.2 1.2 9.3 7 2 5 12 12 12 5 Tetratricopeptide repeat TPR_14 PF13428.6 OQR95665.1 - 1e-15 57.1 13.4 0.00081 20.0 0.0 11.3 10 2 2 12 12 11 3 Tetratricopeptide repeat TPR_17 PF13431.6 OQR95665.1 - 8.2e-13 47.8 15.0 0.4 11.2 0.0 10.4 10 0 0 10 10 10 3 Tetratricopeptide repeat TPR_7 PF13176.6 OQR95665.1 - 1.7e-12 46.4 20.7 0.0009 19.1 0.1 9.4 8 1 1 9 9 9 4 Tetratricopeptide repeat TPR_19 PF14559.6 OQR95665.1 - 1.3e-10 41.6 17.4 0.015 15.8 0.4 8.4 7 1 1 8 8 8 3 Tetratricopeptide repeat TPR_9 PF13371.6 OQR95665.1 - 1.5e-10 41.1 5.0 0.026 14.7 0.1 7.0 7 1 0 7 7 7 2 Tetratricopeptide repeat TPR_10 PF13374.6 OQR95665.1 - 2.2e-09 36.9 19.5 0.045 13.6 0.1 7.4 7 1 1 8 8 8 4 Tetratricopeptide repeat TPR_16 PF13432.6 OQR95665.1 - 5.5e-07 30.1 16.3 0.011 16.3 0.2 8.5 9 1 0 10 10 8 2 Tetratricopeptide repeat ANAPC3 PF12895.7 OQR95665.1 - 4.8e-06 26.7 20.4 0.015 15.6 0.7 7.2 5 2 3 8 8 8 3 Anaphase-promoting complex, cyclosome, subunit 3 Glyco_transf_41 PF13844.6 OQR95665.1 - 0.00046 18.7 5.4 0.0053 15.3 0.0 2.9 3 1 0 3 3 3 2 Glycosyl transferase family 41 TPR_6 PF13174.6 OQR95665.1 - 0.0035 17.9 16.7 2.5 8.9 0.1 8.6 9 0 0 9 9 8 1 Tetratricopeptide repeat Rapsyn_N PF10579.9 OQR95665.1 - 0.0075 16.4 0.2 0.44 10.7 0.1 3.0 2 0 0 2 2 2 1 Rapsyn N-terminal myristoylation and linker region Fis1_TPR_C PF14853.6 OQR95665.1 - 0.087 12.9 21.5 0.29 11.2 0.2 6.4 8 0 0 8 8 8 0 Fis1 C-terminal tetratricopeptide repeat MIT PF04212.18 OQR95665.1 - 0.39 10.8 11.6 4.8 7.3 0.2 6.1 6 0 0 6 6 6 0 MIT (microtubule interacting and transport) domain MFS_1 PF07690.16 OQR95666.1 - 0.00062 18.8 31.3 0.00062 18.8 31.3 3.1 1 1 2 3 3 3 3 Major Facilitator Superfamily Ank_2 PF12796.7 OQR95667.1 - 2.4e-28 98.5 10.3 4.1e-06 27.3 0.9 6.9 2 2 6 8 8 8 8 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OQR95667.1 - 7.3e-17 61.2 18.8 0.17 12.3 0.1 12.5 5 2 8 13 13 13 4 Ankyrin repeats (many copies) Ank_4 PF13637.6 OQR95667.1 - 1.1e-13 51.4 17.3 0.0026 18.3 0.2 9.4 6 4 5 11 11 11 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQR95667.1 - 8.6e-12 44.2 12.1 3.9 8.3 0.0 12.2 12 1 2 14 14 14 1 Ankyrin repeat DUF5049 PF16468.5 OQR95667.1 - 0.00012 21.9 2.1 13 5.8 0.0 6.3 6 1 2 8 8 8 1 Domain of unknown function (DUF5049) Ank PF00023.30 OQR95667.1 - 0.0026 18.1 4.8 2e+02 2.7 0.0 8.2 7 2 1 8 8 8 0 Ankyrin repeat DUF3447 PF11929.8 OQR95667.1 - 0.024 14.6 3.0 19 5.3 0.1 4.4 4 1 0 4 4 4 0 Domain of unknown function (DUF3447) Mononeg_RNA_pol PF00946.19 OQR95667.1 - 0.08 10.6 0.0 0.11 10.2 0.0 1.1 1 0 0 1 1 1 0 Mononegavirales RNA dependent RNA polymerase DnaB_2 PF07261.11 OQR95667.1 - 0.15 11.8 0.2 3.4 7.5 0.0 2.9 2 1 0 2 2 2 0 Replication initiation and membrane attachment Ribonuclease_T2 PF00445.18 OQR95668.1 - 7.1e-26 91.5 0.1 1e-25 91.0 0.1 1.3 1 1 0 1 1 1 1 Ribonuclease T2 family PLDc PF00614.22 OQR95669.1 - 1.2e-15 56.9 0.3 1.3e-07 31.5 0.1 2.8 2 0 0 2 2 2 2 Phospholipase D Active site motif PLDc_2 PF13091.6 OQR95669.1 - 1.4e-15 57.4 0.8 2.7e-09 37.0 0.3 2.9 2 1 0 2 2 2 2 PLD-like domain PX PF00787.24 OQR95669.1 - 0.017 15.1 0.6 0.04 13.9 0.6 1.6 1 0 0 1 1 1 0 PX domain PH PF00169.29 OQR95669.1 - 0.083 13.4 0.1 1.5 9.4 0.0 2.8 3 0 0 3 3 3 0 PH domain ATP_bind_3 PF01171.20 OQR95671.1 - 1.6e-56 190.9 0.0 2.4e-56 190.4 0.0 1.2 1 0 0 1 1 1 1 PP-loop family Asn_synthase PF00733.21 OQR95671.1 - 1.9e-05 24.5 0.1 3.6e-05 23.6 0.0 1.5 2 0 0 2 2 2 1 Asparagine synthase QueC PF06508.13 OQR95671.1 - 3.7e-05 23.3 0.1 0.00016 21.2 0.0 2.0 2 0 0 2 2 2 1 Queuosine biosynthesis protein QueC Enolase_C PF00113.22 OQR95672.1 - 3e-147 489.6 0.3 3.6e-147 489.3 0.3 1.1 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.16 OQR95672.1 - 3.9e-53 179.1 0.0 8e-53 178.1 0.0 1.6 1 0 0 1 1 1 1 Enolase, N-terminal domain MR_MLE_C PF13378.6 OQR95672.1 - 1.1e-06 28.4 0.0 1.9e-06 27.6 0.0 1.3 1 0 0 1 1 1 1 Enolase C-terminal domain-like MAAL_C PF07476.11 OQR95672.1 - 6.4e-06 25.5 0.2 1.2e-05 24.6 0.2 1.4 1 0 0 1 1 1 1 Methylaspartate ammonia-lyase C-terminus Malate_synthase PF01274.22 OQR95673.1 - 1.5e-202 673.6 0.0 1.6e-202 673.4 0.0 1.0 1 0 0 1 1 1 1 Malate synthase hSH3 PF14603.6 OQR95673.1 - 0.13 12.7 0.0 0.28 11.7 0.0 1.5 1 0 0 1 1 1 0 Helically-extended SH3 domain HpcH_HpaI PF03328.14 OQR95673.1 - 0.15 11.2 0.0 0.3 10.2 0.0 1.5 1 0 0 1 1 1 0 HpcH/HpaI aldolase/citrate lyase family HrpB7 PF09486.10 OQR95674.1 - 0.043 14.2 0.4 0.056 13.8 0.4 1.1 1 0 0 1 1 1 0 Bacterial type III secretion protein (HrpB7) DUF4407 PF14362.6 OQR95674.1 - 0.06 12.7 2.0 0.07 12.5 2.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Alpha-2-MRAP_C PF06401.11 OQR95674.1 - 0.083 12.8 4.5 0.39 10.7 4.2 1.9 1 1 0 1 1 1 0 Alpha-2-macroglobulin RAP, C-terminal domain Activator-TraM PF11657.8 OQR95674.1 - 0.088 12.6 0.6 0.13 12.1 0.6 1.3 1 0 0 1 1 1 0 Transcriptional activator TraM MtrG PF04210.13 OQR95674.1 - 0.12 12.3 1.1 1.4 8.9 0.1 2.2 2 0 0 2 2 2 0 Tetrahydromethanopterin S-methyltransferase, subunit G DUF1818 PF08848.11 OQR95674.1 - 0.12 12.5 0.4 0.27 11.3 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1818) Spc7 PF08317.11 OQR95674.1 - 0.17 10.7 3.7 0.23 10.3 3.7 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein Ribosomal_L28 PF00830.19 OQR95675.1 - 7.3e-19 67.7 0.3 1e-18 67.3 0.3 1.2 1 0 0 1 1 1 1 Ribosomal L28 family Peptidase_M42 PF05343.14 OQR95675.1 - 0.15 11.1 0.0 0.17 10.9 0.0 1.1 1 0 0 1 1 1 0 M42 glutamyl aminopeptidase FYVE PF01363.21 OQR95677.1 - 8.6e-17 61.1 12.0 1.6e-16 60.2 12.0 1.5 1 0 0 1 1 1 1 FYVE zinc finger GAF PF01590.26 OQR95677.1 - 3.2e-08 34.3 0.0 6.3e-08 33.3 0.0 1.5 1 0 0 1 1 1 1 GAF domain GAF_3 PF13492.6 OQR95677.1 - 0.014 15.7 0.0 0.35 11.2 0.0 2.4 2 1 0 2 2 2 0 GAF domain Peptidase_S29 PF02907.15 OQR95677.1 - 0.032 14.0 0.0 0.081 12.7 0.0 1.6 1 0 0 1 1 1 0 Hepatitis C virus NS3 protease C1_2 PF03107.16 OQR95677.1 - 0.17 12.2 5.0 0.45 10.9 5.0 1.7 1 0 0 1 1 1 0 C1 domain Sgf11_N PF18519.1 OQR95678.1 - 0.072 12.7 1.3 0.072 12.7 1.3 1.6 2 0 0 2 2 2 0 SAGA-associated factor 11 N-terminal domain SHQ1 PF04925.15 OQR95679.1 - 3.5e-54 183.0 0.4 7.1e-54 182.0 0.4 1.4 1 0 0 1 1 1 1 SHQ1 protein FYVE PF01363.21 OQR95679.1 - 6.2e-27 93.5 29.1 9.7e-15 54.5 10.1 2.7 2 0 0 2 2 2 2 FYVE zinc finger RMI2 PF16100.5 OQR95679.1 - 3.1e-21 75.5 0.1 7.1e-21 74.4 0.1 1.6 1 0 0 1 1 1 1 RecQ-mediated genome instability protein 2 GAF PF01590.26 OQR95679.1 - 1.1e-09 39.0 0.0 0.0024 18.5 0.0 3.2 3 0 0 3 3 3 2 GAF domain FYVE_2 PF02318.16 OQR95679.1 - 0.001 19.3 20.5 0.14 12.3 8.2 2.9 2 0 0 2 2 2 2 FYVE-type zinc finger SpoVT_C PF15714.5 OQR95679.1 - 0.068 13.2 0.0 0.29 11.2 0.0 2.0 2 0 0 2 2 2 0 Stage V sporulation protein T C-terminal, transcription factor RF-1 PF00472.20 OQR95679.1 - 0.41 10.6 2.0 1.4 8.9 2.0 1.8 1 0 0 1 1 1 0 RF-1 domain IBR PF01485.21 OQR95679.1 - 2 8.7 17.9 0.89 9.8 5.3 2.9 2 0 0 2 2 2 0 IBR domain, a half RING-finger domain TMCO5 PF14992.6 OQR95679.1 - 3.8 7.0 8.9 1.3 8.6 5.7 1.8 2 0 0 2 2 2 0 TMCO5 family FYVE PF01363.21 OQR95680.1 - 1.9e-16 59.9 13.2 3.9e-16 58.9 13.2 1.5 1 0 0 1 1 1 1 FYVE zinc finger GAF PF01590.26 OQR95680.1 - 2.1e-09 38.1 0.0 5.2e-09 36.8 0.0 1.7 1 0 0 1 1 1 1 GAF domain GAF_3 PF13492.6 OQR95680.1 - 0.042 14.2 0.0 0.11 12.9 0.0 1.7 2 0 0 2 2 2 0 GAF domain Zf_RING PF16744.5 OQR95680.1 - 1.3 9.2 12.4 7.2 6.8 12.3 2.2 1 1 1 2 2 2 0 KIAA1045 RING finger FYVE PF01363.21 OQR95681.1 - 6e-135 439.6 281.3 8.7e-12 45.0 17.4 17.4 17 0 0 17 17 17 16 FYVE zinc finger GAF PF01590.26 OQR95681.1 - 1.7e-15 57.8 0.1 5e-07 30.4 0.0 3.6 3 0 0 3 3 3 2 GAF domain GAF_2 PF13185.6 OQR95681.1 - 5.1e-09 36.5 0.0 0.0034 17.7 0.0 2.6 2 0 0 2 2 2 2 GAF domain GAF_3 PF13492.6 OQR95681.1 - 0.0012 19.2 0.0 0.0038 17.6 0.0 1.9 1 0 0 1 1 1 1 GAF domain IBP39 PF11422.8 OQR95681.1 - 0.12 12.1 1.3 3.9 7.2 0.1 2.6 2 0 0 2 2 2 0 Initiator binding protein 39 kDa ACOX PF01756.19 OQR95683.1 - 3.1e-46 157.2 0.1 8.7e-46 155.7 0.1 1.8 1 1 0 1 1 1 1 Acyl-CoA oxidase Acyl-CoA_ox_N PF14749.6 OQR95683.1 - 2.8e-27 95.8 0.7 4.9e-27 95.0 0.7 1.4 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_M PF02770.19 OQR95683.1 - 9.9e-15 54.5 0.0 2.1e-14 53.5 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain E1_4HB PF16191.5 OQR95683.1 - 0.15 12.3 0.0 0.53 10.5 0.0 1.9 1 0 0 1 1 1 0 Ubiquitin-activating enzyme E1 four-helix bundle TRAPP PF04051.16 OQR95685.1 - 0.097 12.4 0.0 0.14 11.9 0.0 1.3 1 0 0 1 1 1 0 Transport protein particle (TRAPP) component Glyco_hydro_6 PF01341.17 OQR95686.1 - 4.8e-29 102.0 0.5 8e-29 101.3 0.5 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 6 PH PF00169.29 OQR95686.1 - 2.6e-08 34.3 0.1 8.4e-08 32.7 0.1 1.9 1 0 0 1 1 1 1 PH domain GOLD_2 PF13897.6 OQR95686.1 - 0.0014 19.1 0.1 0.61 10.6 0.0 2.6 1 1 1 2 2 2 2 Golgi-dynamics membrane-trafficking PH_8 PF15409.6 OQR95686.1 - 0.0016 18.6 1.0 0.014 15.7 0.1 2.7 2 1 0 2 2 2 1 Pleckstrin homology domain PTP_tm PF18861.1 OQR95686.1 - 0.029 14.4 0.2 0.079 13.0 0.2 1.7 1 0 0 1 1 1 0 Transmembrane domain of protein tyrosine phosphatase, receptor type J PH_11 PF15413.6 OQR95686.1 - 0.062 13.7 0.0 0.15 12.5 0.0 1.7 1 0 0 1 1 1 0 Pleckstrin homology domain Mito_carr PF00153.27 OQR95688.1 - 2.6e-61 203.6 0.1 1.8e-21 75.9 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein TPR_2 PF07719.17 OQR95689.1 - 0.0049 16.9 4.8 0.17 12.1 0.1 4.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 OQR95689.1 - 0.018 15.2 3.3 0.076 13.3 0.0 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.28 OQR95689.1 - 0.44 10.5 8.3 1.8 8.5 0.0 4.9 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_16 PF13432.6 OQR95689.1 - 3.4 8.4 7.5 4.7 8.0 0.8 4.2 4 1 0 4 4 4 0 Tetratricopeptide repeat Abhydrolase_1 PF00561.20 OQR95690.1 - 4e-20 72.5 0.1 3.7e-19 69.4 0.1 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 OQR95690.1 - 2.3e-19 70.9 0.2 2.3e-19 70.9 0.2 1.5 2 0 0 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 OQR95690.1 - 5.5e-18 65.1 0.0 1.4e-17 63.8 0.0 1.6 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_5 PF12695.7 OQR95690.1 - 0.00023 21.0 0.0 0.00057 19.7 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.20 OQR95690.1 - 0.0006 19.5 0.0 0.00094 18.9 0.0 1.3 1 0 0 1 1 1 1 Putative esterase Palm_thioest PF02089.15 OQR95690.1 - 0.00078 19.3 0.0 0.0011 18.8 0.0 1.2 1 0 0 1 1 1 1 Palmitoyl protein thioesterase DUF915 PF06028.11 OQR95690.1 - 0.001 18.5 0.1 0.004 16.5 0.0 1.8 1 1 1 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF915) Abhydrolase_3 PF07859.13 OQR95690.1 - 0.0012 18.8 0.0 0.0047 16.8 0.0 1.9 2 0 0 2 2 2 1 alpha/beta hydrolase fold Ndr PF03096.14 OQR95690.1 - 0.0018 17.1 0.0 0.0052 15.5 0.0 1.7 2 0 0 2 2 2 1 Ndr family Ser_hydrolase PF06821.13 OQR95690.1 - 0.0036 17.2 0.0 0.0069 16.3 0.0 1.5 1 0 0 1 1 1 1 Serine hydrolase PGAP1 PF07819.13 OQR95690.1 - 0.022 14.5 0.0 0.059 13.1 0.0 1.7 1 1 1 2 2 2 0 PGAP1-like protein Thioesterase PF00975.20 OQR95690.1 - 0.066 13.3 0.1 0.49 10.5 0.0 2.3 3 0 0 3 3 3 0 Thioesterase domain Chlorophyllase2 PF12740.7 OQR95690.1 - 0.11 11.4 0.0 0.2 10.6 0.0 1.4 1 0 0 1 1 1 0 Chlorophyllase enzyme Abhydrolase_2 PF02230.16 OQR95690.1 - 0.15 11.8 0.0 0.56 10.0 0.0 1.9 2 1 1 3 3 3 0 Phospholipase/Carboxylesterase YwiC PF14256.6 OQR95690.1 - 1.5 9.2 14.2 1.5 9.1 0.4 2.7 1 1 1 2 2 2 0 YwiC-like protein DUF2070 PF09843.9 OQR95690.1 - 6.8 4.8 9.0 9.8 4.3 9.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Copine PF07002.16 OQR95691.1 - 1.2e-17 64.2 0.0 1.4e-17 63.9 0.0 1.1 1 0 0 1 1 1 1 Copine AP3D1 PF06375.11 OQR95692.1 - 0.29 11.4 7.2 0.54 10.5 7.2 1.4 1 0 0 1 1 1 0 AP-3 complex subunit delta-1 ATP-synt_E PF05680.12 OQR95692.1 - 0.93 9.9 6.6 0.33 11.3 3.4 1.8 2 0 0 2 2 2 0 ATP synthase E chain Aminotran_5 PF00266.19 OQR95693.1 - 1.4e-33 116.3 0.2 6.4e-20 71.4 0.0 2.6 2 1 0 2 2 2 2 Aminotransferase class-V MOSC PF03473.17 OQR95693.1 - 2.2e-27 95.6 0.0 4.3e-27 94.7 0.0 1.4 1 0 0 1 1 1 1 MOSC domain MOSC_N PF03476.16 OQR95693.1 - 4e-19 68.7 0.0 7.2e-19 67.8 0.0 1.5 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain DUF1664 PF07889.12 OQR95694.1 - 0.0022 18.0 8.6 0.12 12.4 0.0 2.8 2 1 1 3 3 3 2 Protein of unknown function (DUF1664) HisKA_3 PF07730.13 OQR95694.1 - 0.008 16.7 2.2 0.11 13.1 0.1 2.7 2 0 0 2 2 2 1 Histidine kinase ECH_2 PF16113.5 OQR95694.1 - 0.061 12.8 5.8 0.19 11.2 6.5 1.5 2 0 0 2 2 2 0 Enoyl-CoA hydratase/isomerase ApoO PF09769.9 OQR95694.1 - 0.069 13.1 1.2 6.9 6.6 0.0 2.3 1 1 1 2 2 2 0 Apolipoprotein O DUF1043 PF06295.12 OQR95694.1 - 0.12 12.4 11.3 0.098 12.7 7.5 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF1043) TruB_N PF01509.18 OQR95694.1 - 0.14 12.5 1.2 0.7 10.2 0.1 2.2 1 1 1 2 2 2 0 TruB family pseudouridylate synthase (N terminal domain) Exonuc_VII_L PF02601.15 OQR95694.1 - 0.17 11.4 7.4 0.25 10.9 7.4 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit HSBP1 PF06825.12 OQR95694.1 - 0.2 11.5 5.2 1.1 9.2 3.4 3.0 3 0 0 3 3 3 0 Heat shock factor binding protein 1 DUF948 PF06103.11 OQR95694.1 - 0.29 11.4 8.9 1.2 9.4 1.4 2.8 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) SF-assemblin PF06705.11 OQR95694.1 - 0.31 10.3 18.8 0.27 10.6 1.0 3.1 1 1 2 3 3 3 0 SF-assemblin/beta giardin CNP_C_terminal PF17839.1 OQR95694.1 - 1.4 9.7 5.4 0.27 12.0 0.9 2.0 2 1 1 3 3 2 0 C-terminal domain of cyclic nucleotide phosphodiesterase Phasin PF05597.11 OQR95694.1 - 3.1 7.8 6.5 7 6.7 3.2 2.3 2 0 0 2 2 2 0 Poly(hydroxyalcanoate) granule associated protein (phasin) ABC_tran_CTD PF16326.5 OQR95694.1 - 4.5 7.6 8.8 0.83 9.9 2.7 2.7 3 0 0 3 3 3 0 ABC transporter C-terminal domain Fzo_mitofusin PF04799.13 OQR95694.1 - 5.8 6.4 17.4 1.1 8.8 0.5 2.9 1 1 1 2 2 2 0 fzo-like conserved region PRKCSH-like PF12999.7 OQR95694.1 - 8.6 6.1 9.3 1.1 9.0 4.6 1.9 2 0 0 2 2 2 0 Glucosidase II beta subunit-like Ank_2 PF12796.7 OQR95695.1 - 6.6e-31 106.7 5.7 4.5e-09 36.8 2.1 5.1 2 1 3 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQR95695.1 - 9.2e-29 99.5 6.6 9.3e-09 35.7 0.0 7.2 5 2 3 8 8 7 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 OQR95695.1 - 1.7e-26 92.0 6.3 3.7e-09 36.6 0.2 6.9 4 2 2 6 6 6 5 Ankyrin repeats (many copies) Ank PF00023.30 OQR95695.1 - 3.3e-23 81.0 17.9 0.00046 20.5 0.3 9.1 9 0 0 9 9 9 7 Ankyrin repeat Ank_3 PF13606.6 OQR95695.1 - 2.4e-21 73.5 7.1 0.017 15.6 0.1 9.6 9 0 0 9 9 8 5 Ankyrin repeat FYVE PF01363.21 OQR95695.1 - 2.1e-13 50.2 2.9 9.2e-13 48.1 2.9 2.1 1 0 0 1 1 1 1 FYVE zinc finger BTB PF00651.31 OQR95695.1 - 6.6e-12 45.6 0.0 2.3e-11 43.9 0.0 2.0 1 0 0 1 1 1 1 BTB/POZ domain WW PF00397.26 OQR95695.1 - 8.9e-09 35.3 0.2 3.3e-08 33.5 0.2 2.1 1 0 0 1 1 1 1 WW domain PDZ PF00595.24 OQR95695.1 - 0.0007 19.9 0.0 0.0029 17.9 0.0 2.1 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 OQR95695.1 - 0.0036 17.1 0.0 0.01 15.7 0.0 1.8 1 0 0 1 1 1 1 PDZ domain IQ PF00612.27 OQR95695.1 - 0.11 12.4 2.1 0.6 10.0 2.1 2.5 1 0 0 1 1 1 0 IQ calmodulin-binding motif DUF3496 PF12001.8 OQR95695.1 - 0.14 12.5 5.6 0.17 12.3 3.2 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3496) DASH_Spc34 PF08657.10 OQR95695.1 - 0.32 10.8 8.4 0.58 9.9 5.0 2.7 2 0 0 2 2 2 0 DASH complex subunit Spc34 Fib_alpha PF08702.10 OQR95695.1 - 2.7 8.2 13.0 0.93 9.7 8.1 2.9 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family PRKCSH PF07915.13 OQR95696.1 - 2e-17 64.0 0.5 4.4e-13 50.0 0.3 2.9 2 0 0 2 2 2 2 Glucosidase II beta subunit-like protein PRKCSH_1 PF13015.6 OQR95696.1 - 4e-05 23.4 0.0 0.00086 19.0 0.0 2.7 3 1 0 3 3 3 1 Glucosidase II beta subunit-like protein CDK2AP PF09806.9 OQR95696.1 - 0.48 10.5 5.3 10 6.1 0.9 2.3 2 0 0 2 2 2 0 Cyclin-dependent kinase 2-associated protein Coprogen_oxidas PF01218.18 OQR95697.1 - 5.7e-134 445.5 0.0 6.6e-134 445.3 0.0 1.0 1 0 0 1 1 1 1 Coproporphyrinogen III oxidase PAN_4 PF14295.6 OQR95698.1 - 8.9e-22 76.7 19.0 1.4e-08 34.5 1.2 3.5 3 0 0 3 3 3 3 PAN domain PAN_1 PF00024.26 OQR95698.1 - 9.6e-18 63.9 9.9 1.9e-06 27.8 1.4 3.5 1 1 2 3 3 3 3 PAN domain PAN_2 PF08276.11 OQR95698.1 - 0.005 16.9 15.2 0.23 11.6 0.5 3.5 3 0 0 3 3 3 3 PAN-like domain FAP PF07174.11 OQR95698.1 - 0.27 10.6 24.7 0.51 9.7 24.7 1.4 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) PAN_3 PF08277.12 OQR95698.1 - 2.1 8.2 15.0 0.93 9.3 1.6 3.5 3 0 0 3 3 3 0 PAN-like domain AAA_12 PF13087.6 OQR95699.1 - 8e-46 156.2 0.0 8e-46 156.2 0.0 2.1 2 0 0 2 2 1 1 AAA domain AAA_11 PF13086.6 OQR95699.1 - 4e-28 98.9 9.9 4.5e-15 56.1 0.0 3.5 3 0 0 3 3 3 2 AAA domain DNA_pol_A_exo1 PF01612.20 OQR95699.1 - 2.6e-18 66.3 0.1 5.5e-18 65.3 0.1 1.6 1 0 0 1 1 1 1 3'-5' exonuclease AAA_30 PF13604.6 OQR95699.1 - 1.3e-12 47.9 0.0 2.9e-12 46.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 OQR95699.1 - 1.3e-10 41.8 0.0 2.6e-09 37.6 0.0 2.6 2 0 0 2 2 2 1 AAA domain ResIII PF04851.15 OQR95699.1 - 1.4e-08 34.9 0.4 7.8e-08 32.5 0.0 2.5 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit UvrD_C PF13361.6 OQR95699.1 - 0.00018 21.0 0.0 0.00018 21.0 0.0 3.5 4 0 0 4 4 3 1 UvrD-like helicase C-terminal domain UvrD-helicase PF00580.21 OQR95699.1 - 0.00036 20.2 10.6 0.00063 19.3 0.0 3.4 3 1 0 3 3 3 1 UvrD/REP helicase N-terminal domain Helicase_RecD PF05127.14 OQR95699.1 - 0.00056 19.8 0.0 0.004 17.0 0.0 2.6 1 1 0 1 1 1 1 Helicase AAA_7 PF12775.7 OQR95699.1 - 0.0091 15.5 0.0 0.021 14.4 0.0 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_22 PF13401.6 OQR95699.1 - 0.012 15.9 0.0 0.06 13.6 0.0 2.3 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 OQR95699.1 - 0.016 15.7 0.0 0.036 14.5 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) UvrD_C_2 PF13538.6 OQR95699.1 - 0.066 13.1 0.1 0.2 11.5 0.1 1.9 1 1 0 1 1 1 0 UvrD-like helicase C-terminal domain Ricin_B_lectin PF00652.22 OQR95700.1 - 3.2e-18 66.2 4.6 1.6e-11 44.6 0.8 2.5 2 0 0 2 2 2 2 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.6 OQR95700.1 - 2.7e-10 40.8 1.1 0.044 14.5 0.0 3.4 2 1 1 3 3 3 3 Ricin-type beta-trefoil lectin domain-like CDtoxinA PF03498.14 OQR95700.1 - 0.00037 20.1 0.9 0.022 14.3 0.3 2.6 2 1 0 2 2 2 2 Cytolethal distending toxin A/C domain BK_channel_a PF03493.18 OQR95701.1 - 7e-19 67.8 0.1 9.5e-19 67.4 0.1 1.2 1 0 0 1 1 1 1 Calcium-activated BK potassium channel alpha subunit S_100 PF01023.19 OQR95701.1 - 0.037 13.7 0.0 0.079 12.7 0.0 1.5 1 0 0 1 1 1 0 S-100/ICaBP type calcium binding domain BK_channel_a PF03493.18 OQR95703.1 - 2.5e-14 53.2 0.0 6.1e-14 52.0 0.0 1.7 1 0 0 1 1 1 1 Calcium-activated BK potassium channel alpha subunit Ion_trans_2 PF07885.16 OQR95703.1 - 1.2e-09 38.0 0.2 1.2e-09 38.0 0.2 2.5 2 0 0 2 2 2 1 Ion channel ANAPC4_WD40 PF12894.7 OQR95704.1 - 5.3e-15 55.5 1.9 0.035 14.4 0.0 5.8 4 1 2 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 OQR95704.1 - 2.7e-09 37.5 0.9 0.056 14.3 0.0 6.1 5 1 0 5 5 5 2 WD domain, G-beta repeat eIF2A PF08662.11 OQR95704.1 - 1.6e-05 24.9 1.8 0.26 11.1 0.1 4.3 3 1 1 4 4 4 2 Eukaryotic translation initiation factor eIF2A IKI3 PF04762.12 OQR95704.1 - 9e-05 20.7 2.7 0.26 9.2 0.1 3.2 2 1 1 3 3 3 2 IKI3 family PD40 PF07676.12 OQR95704.1 - 0.002 18.0 5.4 11 6.1 0.0 5.8 6 1 1 7 7 7 2 WD40-like Beta Propeller Repeat Proteasome_A_N PF10584.9 OQR95704.1 - 0.027 14.1 0.4 11 5.8 0.0 3.5 3 0 0 3 3 3 0 Proteasome subunit A N-terminal signature DPPIV_N PF00930.21 OQR95704.1 - 0.073 11.8 0.1 3.2 6.4 0.0 3.3 3 0 0 3 3 3 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region Coatomer_WDAD PF04053.14 OQR95704.1 - 0.12 11.4 0.6 4.4 6.2 0.3 3.1 2 1 0 2 2 2 0 Coatomer WD associated region PB1 PF00564.24 OQR95705.1 - 0.065 13.2 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 PB1 domain Amidohydro_3 PF07969.11 OQR95706.1 - 9.1e-84 282.6 0.0 1.1e-83 282.4 0.0 1.0 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_1 PF01979.20 OQR95706.1 - 3.1e-17 62.9 0.1 4.6e-15 55.8 0.0 2.2 2 0 0 2 2 2 2 Amidohydrolase family Aa_trans PF01490.18 OQR95707.1 - 1.9e-38 132.3 20.2 2.8e-38 131.7 20.2 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Aa_trans PF01490.18 OQR95708.1 - 3.1e-13 49.2 10.5 3.7e-13 49.0 10.5 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 OQR95708.1 - 1.1e-06 28.0 8.9 1.2e-06 27.8 8.9 1.0 1 0 0 1 1 1 1 Tryptophan/tyrosine permease family Aminotran_1_2 PF00155.21 OQR95709.1 - 2.1e-43 148.9 0.0 2.5e-43 148.6 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 OQR95709.1 - 0.00028 19.5 0.0 0.00043 18.9 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 OQR95709.1 - 0.001 18.1 0.0 0.0016 17.4 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 OQR95709.1 - 0.0061 15.9 0.0 0.013 14.8 0.0 1.3 1 1 0 1 1 1 1 Beta-eliminating lyase OKR_DC_1 PF01276.20 OQR95709.1 - 0.15 10.7 0.1 0.53 8.9 0.1 1.8 1 1 0 1 1 1 0 Orn/Lys/Arg decarboxylase, major domain Peptidase_S74 PF13884.6 OQR95710.1 - 8.5e-18 64.4 0.0 1.6e-17 63.5 0.0 1.5 1 0 0 1 1 1 1 Chaperone of endosialidase EGF_2 PF07974.13 OQR95710.1 - 4.6e-07 30.1 27.9 0.0002 21.7 7.4 2.5 2 0 0 2 2 2 2 EGF-like domain EGF PF00008.27 OQR95710.1 - 0.00075 19.8 24.5 0.015 15.6 5.1 3.2 3 0 0 3 3 3 2 EGF-like domain DUF4763 PF15960.5 OQR95710.1 - 0.19 11.0 1.4 0.35 10.1 1.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4763) hEGF PF12661.7 OQR95710.1 - 0.3 11.8 19.8 0.45 11.2 6.6 2.8 2 0 0 2 2 2 0 Human growth factor-like EGF Laminin_EGF PF00053.24 OQR95710.1 - 0.55 10.4 24.6 0.59 10.3 8.3 2.5 2 0 0 2 2 2 0 Laminin EGF domain SlyX PF04102.12 OQR95710.1 - 0.7 10.5 5.5 1.5 9.5 3.1 2.5 3 0 0 3 3 3 0 SlyX EGF_alliinase PF04863.13 OQR95710.1 - 6.3 7.3 17.4 2.3 8.7 6.7 2.7 2 0 0 2 2 2 0 Alliinase EGF-like domain Ank_2 PF12796.7 OQR95711.1 - 1.7e-15 57.4 4.9 6.2e-07 29.9 0.4 2.9 1 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQR95711.1 - 3e-13 50.0 7.3 6.4e-06 26.6 0.2 4.6 3 2 2 5 5 5 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 OQR95711.1 - 1.4e-11 44.4 5.2 0.037 14.4 0.2 6.0 1 1 5 6 6 6 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQR95711.1 - 1.1e-06 28.5 0.4 25 5.9 0.0 5.7 6 0 0 6 6 6 0 Ankyrin repeat Ank PF00023.30 OQR95711.1 - 0.0005 20.4 0.4 6 7.5 0.0 4.4 1 1 1 2 2 2 1 Ankyrin repeat Cys_rich_CPXG PF14255.6 OQR95711.1 - 0.012 15.5 0.3 0.022 14.6 0.3 1.5 1 0 0 1 1 1 0 Cysteine-rich CPXCG DUF3322 PF11795.8 OQR95711.1 - 0.013 15.6 0.0 1.7 8.6 0.0 2.5 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria N-term (DUF3322) Cys_rich_KTR PF14205.6 OQR95711.1 - 0.054 13.3 0.0 0.12 12.2 0.0 1.6 1 0 0 1 1 1 0 Cysteine-rich KTR ISN1 PF06437.11 OQR95712.1 - 1.8e-98 330.1 0.0 2.2e-98 329.8 0.0 1.0 1 0 0 1 1 1 1 IMP-specific 5'-nucleotidase M16C_assoc PF08367.11 OQR95713.1 - 2.1e-54 184.3 0.3 5.4e-54 183.0 0.3 1.7 1 0 0 1 1 1 1 Peptidase M16C associated Peptidase_M16_C PF05193.21 OQR95713.1 - 1.2e-21 77.6 0.0 3.4e-14 53.3 0.0 3.9 4 0 0 4 4 4 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 OQR95713.1 - 1.6e-10 41.2 0.0 1.4e-08 34.9 0.0 2.9 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) XPC-binding PF09280.11 OQR95713.1 - 0.096 12.4 0.3 0.34 10.7 0.3 2.0 1 0 0 1 1 1 0 XPC-binding domain Ras PF00071.22 OQR95716.1 - 1.2e-42 145.3 0.0 1.5e-42 145.0 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OQR95716.1 - 2.4e-16 60.0 0.0 3.7e-16 59.4 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase KHA PF11834.8 OQR95716.1 - 7.7e-12 45.1 0.0 1.5e-11 44.2 0.0 1.5 1 0 0 1 1 1 1 KHA, dimerisation domain of potassium ion channel Arf PF00025.21 OQR95716.1 - 1.5e-07 31.0 0.0 2e-07 30.6 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 OQR95716.1 - 4.9e-06 26.2 0.0 1.6e-05 24.6 0.0 1.7 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 OQR95716.1 - 0.00085 19.4 0.0 0.0014 18.7 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 OQR95716.1 - 0.043 13.7 0.0 6.7 6.6 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase NB-ARC PF00931.22 OQR95716.1 - 0.077 12.2 0.0 0.19 10.9 0.0 1.6 2 0 0 2 2 2 0 NB-ARC domain ATP_bind_1 PF03029.17 OQR95716.1 - 0.19 11.4 1.7 0.29 10.9 0.1 1.8 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein Ras PF00071.22 OQR95717.1 - 1.6e-41 141.6 0.0 2.3e-41 141.1 0.0 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OQR95717.1 - 1.3e-16 60.9 0.0 2.1e-16 60.3 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase KHA PF11834.8 OQR95717.1 - 6.2e-10 39.0 0.0 1.3e-09 38.0 0.0 1.5 1 0 0 1 1 1 1 KHA, dimerisation domain of potassium ion channel Arf PF00025.21 OQR95717.1 - 1.7e-07 30.9 0.0 2.3e-07 30.4 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 OQR95717.1 - 4e-06 26.5 0.0 1.9e-05 24.3 0.0 1.9 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 OQR95717.1 - 6.2e-05 23.0 0.0 0.0001 22.3 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 OQR95717.1 - 0.038 13.9 0.0 8.4 6.3 0.0 2.3 2 0 0 2 2 2 0 RsgA GTPase AAA_16 PF13191.6 OQR95717.1 - 0.078 13.4 0.1 0.16 12.3 0.1 1.7 1 1 0 1 1 1 0 AAA ATPase domain Fer2 PF00111.27 OQR95718.1 - 3.2e-11 43.0 0.2 4.3e-11 42.6 0.2 1.1 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Nuc_sug_transp PF04142.15 OQR95719.1 - 3.8e-31 108.4 15.3 5.2e-31 108.0 15.3 1.1 1 0 0 1 1 1 1 Nucleotide-sugar transporter PUNUT PF16913.5 OQR95719.1 - 1.5e-06 27.7 5.5 1.5e-06 27.7 5.5 1.6 2 0 0 2 2 2 1 Purine nucleobase transmembrane transport EamA PF00892.20 OQR95719.1 - 0.025 14.8 31.0 0.054 13.7 11.4 2.2 2 0 0 2 2 2 0 EamA-like transporter family DUF4199 PF13858.6 OQR95719.1 - 0.044 14.2 0.8 0.044 14.2 0.8 2.7 3 1 0 3 3 3 0 Protein of unknown function (DUF4199) DUF4293 PF14126.6 OQR95719.1 - 0.41 10.9 10.3 1.8 8.8 10.3 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4293) FAST_1 PF06743.15 OQR95720.1 - 1e-06 28.6 1.1 0.71 9.9 0.1 4.0 2 1 2 4 4 4 3 FAST kinase-like protein, subdomain 1 HBD PF18534.1 OQR95720.1 - 0.064 13.4 0.1 0.17 12.0 0.2 1.8 1 1 0 1 1 1 0 Helical bundle domain DUF1601 PF07671.11 OQR95720.1 - 0.11 12.3 4.3 0.31 11.0 0.1 3.4 4 0 0 4 4 4 0 Protein of unknown function (DUF1601) RRS1 PF04939.12 OQR95722.1 - 2.3e-54 183.6 7.1 2.3e-54 183.6 7.1 2.7 2 1 1 3 3 3 1 Ribosome biogenesis regulatory protein (RRS1) DUF1845 PF08900.11 OQR95722.1 - 0.067 12.9 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1845) EF1_GNE PF00736.19 OQR95723.1 - 3.4e-24 84.8 1.0 7.9e-24 83.7 1.0 1.7 1 0 0 1 1 1 1 EF-1 guanine nucleotide exchange domain SET PF00856.28 OQR95723.1 - 2.7e-12 47.4 0.0 3.3e-05 24.3 0.0 2.5 2 0 0 2 2 2 2 SET domain UNC119_bdg PF15435.6 OQR95723.1 - 0.055 13.0 0.0 0.45 10.0 0.0 2.1 2 0 0 2 2 2 0 UNC119-binding protein C5orf30 homologue SelK_SelG PF10961.8 OQR95723.1 - 0.16 12.6 6.5 0.43 11.2 6.5 1.7 1 0 0 1 1 1 0 Selenoprotein SelK_SelG GTP_EFTU PF00009.27 OQR95724.1 - 2.4e-44 151.2 0.0 3.8e-44 150.6 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 OQR95724.1 - 7.3e-23 81.0 0.0 1.8e-22 79.8 0.0 1.7 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain MMR_HSR1 PF01926.23 OQR95724.1 - 3.4e-06 27.1 0.1 0.0021 18.1 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.25 OQR95724.1 - 0.00014 22.2 0.3 0.00036 20.9 0.3 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 HBS1_N PF08938.10 OQR95724.1 - 0.00048 20.4 0.9 0.00099 19.4 0.3 1.8 2 0 0 2 2 2 1 HBS1 N-terminus FancD2 PF14631.6 OQR95725.1 - 5.9e-99 332.2 30.3 2.9e-63 213.9 23.3 3.2 2 1 0 2 2 2 2 Fanconi anaemia protein FancD2 nuclease FANCI_S2 PF14676.6 OQR95725.1 - 4.2e-05 23.9 3.7 4.4e-05 23.9 0.1 3.0 3 0 0 3 3 3 1 FANCI solenoid 2 FANCI_S1 PF14675.6 OQR95725.1 - 0.02 14.5 2.8 0.057 13.0 2.8 1.7 1 0 0 1 1 1 0 FANCI solenoid 1 Exo70 PF03081.15 OQR95725.1 - 0.19 10.7 2.3 7.6 5.5 0.0 3.0 2 1 0 2 2 2 0 Exo70 exocyst complex subunit MFS_1_like PF12832.7 OQR95726.1 - 2.9e-53 181.1 33.0 7.2e-53 179.8 33.0 1.5 1 1 0 1 1 1 1 MFS_1 like family MFS_1 PF07690.16 OQR95726.1 - 4.5e-20 71.9 64.1 2.1e-15 56.6 37.9 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Nuc_H_symport PF03825.16 OQR95726.1 - 1.9e-10 40.3 28.6 2.5e-10 39.9 28.6 1.0 1 0 0 1 1 1 1 Nucleoside H+ symporter LacY_symp PF01306.19 OQR95726.1 - 0.00043 19.2 26.5 0.0023 16.8 18.9 2.6 1 1 1 2 2 2 2 LacY proton/sugar symporter PrgI PF12666.7 OQR95726.1 - 0.45 11.2 0.1 0.45 11.2 0.1 4.9 4 1 2 6 6 6 0 PrgI family protein Pkinase PF00069.25 OQR95727.1 - 3.2e-59 200.4 0.0 5.2e-59 199.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain cNMP_binding PF00027.29 OQR95727.1 - 1.8e-44 149.7 0.2 1.9e-16 59.9 0.0 3.6 3 0 0 3 3 3 3 Cyclic nucleotide-binding domain Pkinase_Tyr PF07714.17 OQR95727.1 - 2.6e-27 95.7 0.0 4.5e-27 95.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Asn_synthase PF00733.21 OQR95727.1 - 1.1e-21 77.9 0.1 8.7e-09 35.5 0.1 3.3 2 1 1 3 3 3 3 Asparagine synthase GATase_7 PF13537.6 OQR95727.1 - 7.9e-07 29.0 0.0 2.1e-06 27.6 0.0 1.7 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.6 OQR95727.1 - 0.00028 21.1 0.0 0.00074 19.7 0.0 1.8 1 0 0 1 1 1 1 Glutamine amidotransferase domain PCMT PF01135.19 OQR95733.1 - 3.8e-23 82.4 0.0 4.4e-19 69.1 0.0 2.1 2 0 0 2 2 2 2 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) WSD PF15613.6 OQR95733.1 - 0.084 13.4 0.0 0.18 12.3 0.0 1.6 1 0 0 1 1 1 0 Williams-Beuren syndrome DDT (WSD), D-TOX E motif Na_trans_assoc PF06512.13 OQR95733.1 - 0.34 11.2 6.8 0.11 12.8 3.0 1.8 2 0 0 2 2 2 0 Sodium ion transport-associated CorA PF01544.18 OQR95734.1 - 2e-08 34.0 25.7 0.0009 18.6 10.7 3.4 2 2 0 2 2 2 2 CorA-like Mg2+ transporter protein Coat_F PF07875.12 OQR95734.1 - 0.064 13.5 0.7 23 5.3 0.1 2.9 2 0 0 2 2 2 0 Coat F domain TruB_C_2 PF16198.5 OQR95734.1 - 0.21 11.8 3.2 11 6.3 0.2 4.2 4 0 0 4 4 4 0 tRNA pseudouridylate synthase B C-terminal domain DUF2569 PF10754.9 OQR95734.1 - 1.6 9.2 12.8 1.5 9.3 4.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2569) Phage_holin_3_6 PF07332.11 OQR95734.1 - 4.7 7.3 14.6 3.2 7.8 3.3 2.4 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III Myb_DNA-binding PF00249.31 OQR95735.1 - 2e-20 72.7 1.9 6.6e-09 35.8 0.0 3.4 4 0 0 4 4 4 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OQR95735.1 - 2e-06 27.9 2.9 0.005 17.1 0.0 3.1 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OQR95735.1 - 0.0076 16.1 0.4 1.7 8.6 0.0 3.1 3 1 0 3 3 3 1 Myb DNA-binding like MNR PF15718.5 OQR95735.1 - 0.03 12.5 0.0 0.065 11.4 0.0 1.3 1 1 0 1 1 1 0 Protein moonraker Linker_histone PF00538.19 OQR95737.1 - 1.5e-17 63.7 0.1 1.5e-17 63.7 0.1 4.2 3 1 0 3 3 3 1 linker histone H1 and H5 family DUF5057 PF16480.5 OQR95737.1 - 5.9 6.1 19.0 3.9 6.7 14.5 2.0 1 1 0 2 2 2 0 Domain of unknown function (DUF5057) WW PF00397.26 OQR95738.1 - 5.4e-13 48.8 0.5 1.3e-12 47.5 0.5 1.7 1 0 0 1 1 1 1 WW domain IQ PF00612.27 OQR95739.1 - 0.003 17.2 1.1 0.003 17.2 1.1 3.6 3 0 0 3 3 3 1 IQ calmodulin-binding motif PhoLip_ATPase_C PF16212.5 OQR95740.1 - 2.4e-67 227.3 23.6 2.4e-67 227.3 23.6 2.3 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 OQR95740.1 - 8.4e-18 63.8 2.5 1.3e-17 63.2 0.8 2.2 2 0 0 2 2 2 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 OQR95740.1 - 5.5e-12 46.4 0.1 0.0001 22.7 0.0 2.9 1 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 OQR95740.1 - 2.8e-08 33.7 0.0 2e-07 31.0 0.0 2.2 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 OQR95740.1 - 1.7e-06 27.9 0.0 6e-06 26.2 0.0 1.8 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 OQR95740.1 - 1.7e-05 24.4 0.8 3.7e-05 23.3 0.0 2.0 2 0 0 2 2 2 1 E1-E2 ATPase S6PP PF05116.13 OQR95740.1 - 0.13 11.7 0.0 0.28 10.7 0.0 1.5 1 0 0 1 1 1 0 Sucrose-6F-phosphate phosphohydrolase DDHD PF02862.17 OQR95741.1 - 0.79 9.8 6.0 2.9 8.0 6.3 1.9 1 1 0 1 1 1 0 DDHD domain DUF2076 PF09849.9 OQR95741.1 - 4.5 7.2 13.1 10 6.1 13.1 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) DUF3278 PF11683.8 OQR95743.1 - 2.8 8.0 9.6 11 6.1 0.3 3.7 3 1 1 4 4 4 0 Protein of unknown function (DUF3278) APH PF01636.23 OQR95744.1 - 2.6e-11 43.9 0.0 3.8e-11 43.4 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 OQR95744.1 - 0.17 11.5 0.0 0.23 11.0 0.0 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase DUF4246 PF14033.6 OQR95745.1 - 5.7e-37 127.9 0.0 7e-37 127.6 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4246) ABC_tran PF00005.27 OQR95746.1 - 1.7e-41 142.0 0.0 2.5e-30 105.8 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 OQR95746.1 - 3.5e-20 72.8 12.7 5.5e-20 72.2 12.7 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.19 OQR95746.1 - 3.5e-07 29.9 1.8 0.0093 15.4 0.1 3.2 2 1 1 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 OQR95746.1 - 0.0039 17.1 0.1 1.8 8.3 0.0 2.6 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system MMR_HSR1 PF01926.23 OQR95746.1 - 0.0056 16.7 0.1 0.017 15.2 0.1 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase DEAD PF00270.29 OQR95746.1 - 0.027 14.3 0.1 0.12 12.1 0.0 2.0 2 0 0 2 2 2 0 DEAD/DEAH box helicase RsgA_GTPase PF03193.16 OQR95746.1 - 0.15 11.9 0.0 0.3 11.0 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase Phlebovirus_G1 PF07243.11 OQR95746.1 - 0.16 10.3 0.0 0.25 9.7 0.0 1.2 1 0 0 1 1 1 0 Phlebovirus glycoprotein G1 Peptidase_C1 PF00112.23 OQR95747.1 - 2.8e-58 197.6 9.6 3.5e-58 197.3 9.6 1.1 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.15 OQR95747.1 - 4.2e-05 22.5 0.9 0.15 10.8 0.1 2.2 2 0 0 2 2 2 2 Peptidase C1-like family GTP1_OBG PF01018.22 OQR95749.1 - 1.8e-33 115.3 3.5 2.6e-33 114.8 3.5 1.2 1 0 0 1 1 1 1 GTP1/OBG MMR_HSR1 PF01926.23 OQR95749.1 - 3.5e-24 85.1 0.0 2.4e-23 82.4 0.0 2.3 3 0 0 3 3 3 1 50S ribosome-binding GTPase FeoB_N PF02421.18 OQR95749.1 - 2.6e-10 40.0 0.0 1.9e-09 37.3 0.0 2.1 1 1 0 1 1 1 1 Ferrous iron transport protein B Arf PF00025.21 OQR95749.1 - 0.00022 20.8 0.0 0.00063 19.2 0.0 1.8 2 0 0 2 2 2 1 ADP-ribosylation factor family AAA_18 PF13238.6 OQR95749.1 - 0.0015 19.1 0.3 0.11 13.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain MMR_HSR1_C PF08438.10 OQR95749.1 - 0.002 18.7 0.0 0.01 16.4 0.0 2.1 2 0 0 2 2 2 1 GTPase of unknown function C-terminal YL1 PF05764.13 OQR95749.1 - 0.028 14.6 8.3 0.042 14.0 8.3 1.2 1 0 0 1 1 1 0 YL1 nuclear protein ABC_tran PF00005.27 OQR95749.1 - 0.069 13.7 0.0 0.17 12.4 0.0 1.6 1 0 0 1 1 1 0 ABC transporter Dynamin_N PF00350.23 OQR95749.1 - 0.092 12.8 0.0 9.3 6.3 0.0 2.7 1 1 0 2 2 2 0 Dynamin family MMR_HSR1_Xtn PF16897.5 OQR95749.1 - 0.11 12.6 0.0 0.22 11.6 0.0 1.4 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain GTP_EFTU PF00009.27 OQR95749.1 - 0.11 12.0 0.0 7 6.1 0.0 2.8 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain TIR_2 PF13676.6 OQR95751.1 - 1.5e-07 32.0 0.0 3.6e-07 30.8 0.0 1.7 1 0 0 1 1 1 1 TIR domain Laminin_G_3 PF13385.6 OQR95751.1 - 4.8e-07 30.0 0.0 0.0061 16.7 0.0 2.5 2 0 0 2 2 2 2 Concanavalin A-like lectin/glucanases superfamily SAM_1 PF00536.30 OQR95751.1 - 0.0005 20.5 0.0 0.0013 19.1 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Laminin_G_2 PF02210.24 OQR95751.1 - 0.079 13.5 0.0 6.3 7.4 0.0 2.4 2 0 0 2 2 2 0 Laminin G domain SAM_2 PF07647.17 OQR95751.1 - 0.12 12.5 0.0 0.33 11.1 0.0 1.7 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) DUF1080 PF06439.11 OQR95751.1 - 0.15 12.1 0.0 10 6.2 0.0 2.5 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1080) BSD PF03909.17 OQR95752.1 - 0.013 15.4 1.3 0.036 14.1 0.0 2.4 3 0 0 3 3 3 0 BSD domain Prp31_C PF09785.9 OQR95753.1 - 1.1e-35 123.1 5.1 1.9e-35 122.4 5.1 1.3 1 0 0 1 1 1 1 Prp31 C terminal domain Nop PF01798.18 OQR95753.1 - 1.8e-06 27.6 0.0 3.2e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 snoRNA binding domain, fibrillarin DUF3236 PF11576.8 OQR95753.1 - 0.1 12.3 0.0 0.16 11.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3236) DUSP PF06337.12 OQR95754.1 - 2.4e-16 60.1 0.9 5.5e-16 59.0 0.9 1.6 1 0 0 1 1 1 1 DUSP domain C2 PF00168.30 OQR95754.1 - 4.8e-09 36.4 0.0 7.5e-09 35.8 0.0 1.3 1 0 0 1 1 1 1 C2 domain 2OG-FeII_Oxy PF03171.20 OQR95755.1 - 6.4e-05 23.4 0.0 0.00011 22.6 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Pkinase PF00069.25 OQR95756.1 - 8.7e-62 208.9 0.0 1.7e-61 207.9 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain LRR_6 PF13516.6 OQR95756.1 - 8.9e-32 106.4 25.9 0.00018 21.3 0.4 14.1 14 0 0 14 14 14 8 Leucine Rich repeat Pkinase_Tyr PF07714.17 OQR95756.1 - 1.7e-29 102.9 0.0 3e-29 102.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase LRR_4 PF12799.7 OQR95756.1 - 4.7e-12 45.9 33.2 0.29 11.6 0.2 12.5 9 5 6 15 15 15 8 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 OQR95756.1 - 1.1e-10 40.6 4.1 16 6.5 0.0 11.6 13 1 0 13 13 13 1 Leucine Rich Repeat LRR_8 PF13855.6 OQR95756.1 - 3.3e-07 29.9 28.3 0.12 12.1 0.3 11.5 11 4 0 11 11 11 4 Leucine rich repeat CTD_bind PF04818.13 OQR95757.1 - 5.4e-12 46.4 0.1 3.2e-11 43.9 0.0 2.4 2 0 0 2 2 2 1 RNA polymerase II-binding domain. Orthopox_F7 PF05813.12 OQR95757.1 - 0.049 13.8 0.4 5.9 7.1 0.0 2.7 2 0 0 2 2 2 0 Orthopoxvirus F7 protein DUF1682 PF07946.14 OQR95757.1 - 5.6 6.1 15.6 64 2.6 14.7 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1682) WD40 PF00400.32 OQR95758.1 - 2.2e-17 63.1 11.0 9.9e-05 23.0 0.1 5.2 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OQR95758.1 - 4.3e-07 30.2 0.0 0.28 11.5 0.1 4.3 1 1 3 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain DUF3717 PF12512.8 OQR95758.1 - 0.027 14.3 0.0 0.086 12.7 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3717) AMPK1_CBM PF16561.5 OQR95758.1 - 0.028 14.6 0.6 0.2 11.9 0.0 2.6 3 0 0 3 3 3 0 Glycogen recognition site of AMP-activated protein kinase Ge1_WD40 PF16529.5 OQR95758.1 - 0.055 12.4 0.1 0.36 9.7 0.1 2.3 1 1 1 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Annexin PF00191.20 OQR95759.1 - 7.3e-49 163.7 0.4 2.1e-10 40.5 0.0 4.1 4 0 0 4 4 4 4 Annexin Ank_2 PF12796.7 OQR95761.1 - 2.7e-12 47.1 0.1 2e-07 31.5 0.0 3.8 3 1 1 4 4 4 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQR95761.1 - 1e-07 32.4 0.5 0.012 16.2 0.1 5.2 5 1 0 5 5 5 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 OQR95761.1 - 4.6e-07 30.0 0.4 0.27 11.6 0.0 6.1 3 1 5 8 8 8 1 Ankyrin repeats (many copies) DUF3447 PF11929.8 OQR95761.1 - 3.7e-05 23.6 0.1 0.51 10.3 0.0 4.3 4 1 1 5 5 5 2 Domain of unknown function (DUF3447) Ank_3 PF13606.6 OQR95761.1 - 0.00011 22.3 0.7 28 5.7 0.0 6.9 8 0 0 8 8 8 1 Ankyrin repeat DUF5049 PF16468.5 OQR95761.1 - 0.079 12.9 0.8 1.1 9.2 0.0 3.2 4 0 0 4 4 4 0 Domain of unknown function (DUF5049) Ank_2 PF12796.7 OQR95762.1 - 1.5e-13 51.2 1.0 3.7e-05 24.2 0.5 4.0 3 2 1 4 4 4 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQR95762.1 - 4.2e-12 46.3 1.1 0.00027 21.4 0.2 5.1 4 2 1 5 5 5 3 Ankyrin repeats (many copies) DUF3447 PF11929.8 OQR95762.1 - 1.2e-08 34.8 3.1 0.0013 18.6 0.1 4.3 2 2 3 5 5 5 2 Domain of unknown function (DUF3447) Ank_3 PF13606.6 OQR95762.1 - 8e-08 32.0 1.7 3.4 8.5 0.0 6.7 6 1 1 7 7 7 2 Ankyrin repeat Ank_5 PF13857.6 OQR95762.1 - 1.5e-06 28.3 0.6 0.43 11.0 0.1 4.8 3 1 2 5 5 5 3 Ankyrin repeats (many copies) Ank PF00023.30 OQR95762.1 - 0.24 11.9 0.4 75 4.0 0.0 4.6 3 3 0 3 3 3 0 Ankyrin repeat DHC_N1 PF08385.12 OQR95763.1 - 6e-155 517.1 0.1 6e-155 517.1 0.1 4.3 4 1 0 4 4 3 1 Dynein heavy chain, N-terminal region 1 AAA_6 PF12774.7 OQR95763.1 - 3.3e-154 512.7 0.0 8.8e-154 511.3 0.0 1.8 1 0 0 1 1 1 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 OQR95763.1 - 1.6e-122 409.4 13.6 1.6e-122 409.4 13.6 3.5 3 0 0 3 3 3 1 Dynein heavy chain, N-terminal region 2 AAA_7 PF12775.7 OQR95763.1 - 2.8e-77 258.3 0.9 1.3e-73 246.4 0.0 3.5 3 0 0 3 3 3 2 P-loop containing dynein motor region Dynein_AAA_lid PF17852.1 OQR95763.1 - 4.1e-25 88.3 0.1 2.3e-23 82.7 0.0 3.2 2 0 0 2 2 2 1 Dynein heavy chain AAA lid domain AAA_5 PF07728.14 OQR95763.1 - 5.2e-18 65.4 0.0 1.7e-09 37.8 0.0 4.6 3 1 0 3 3 3 3 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 OQR95763.1 - 6.2e-08 33.0 0.1 0.017 15.4 0.0 4.9 4 0 0 4 4 4 1 AAA domain AAA PF00004.29 OQR95763.1 - 1e-05 26.0 0.0 0.21 12.0 0.0 3.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 OQR95763.1 - 0.00014 22.3 1.7 0.2 12.0 0.0 4.9 5 1 1 6 6 4 1 AAA ATPase domain AAA_18 PF13238.6 OQR95763.1 - 0.00083 19.9 0.0 2.4 8.7 0.0 4.1 4 0 0 4 4 3 1 AAA domain AAA_29 PF13555.6 OQR95763.1 - 0.0022 17.7 0.3 0.94 9.3 0.2 3.1 2 0 0 2 2 2 1 P-loop containing region of AAA domain Roc PF08477.13 OQR95763.1 - 0.0035 17.6 0.2 0.25 11.6 0.1 3.2 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase TniB PF05621.11 OQR95763.1 - 0.0039 16.6 0.1 4 6.8 0.0 3.3 3 0 0 3 3 3 1 Bacterial TniB protein AAA_24 PF13479.6 OQR95763.1 - 0.011 15.5 0.8 9.9 5.8 0.1 4.0 3 0 0 3 3 3 0 AAA domain MMR_HSR1 PF01926.23 OQR95763.1 - 0.011 15.7 1.0 5 7.2 0.1 3.7 3 0 0 3 3 3 0 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 OQR95763.1 - 0.012 15.5 0.5 4.7 7.1 0.1 3.0 2 0 0 2 2 2 0 RsgA GTPase ATP-synt_ab PF00006.25 OQR95763.1 - 0.017 14.7 0.3 0.5 10.0 0.0 2.9 3 0 0 3 3 3 0 ATP synthase alpha/beta family, nucleotide-binding domain ABC_tran PF00005.27 OQR95763.1 - 0.033 14.7 0.2 12 6.4 0.0 3.8 2 0 0 2 2 2 0 ABC transporter DUF853 PF05872.12 OQR95763.1 - 0.034 12.8 0.9 8.7 4.8 0.0 3.1 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF853) ATPase_2 PF01637.18 OQR95763.1 - 0.041 13.8 1.0 3.1 7.6 0.0 3.8 4 0 0 4 4 4 0 ATPase domain predominantly from Archaea RNA_helicase PF00910.22 OQR95763.1 - 0.042 14.3 0.6 41 4.6 0.0 4.1 4 0 0 4 4 3 0 RNA helicase AAA_19 PF13245.6 OQR95763.1 - 0.042 14.2 0.5 5.7 7.3 0.0 3.1 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 OQR95763.1 - 0.054 13.2 1.1 23 4.6 0.1 3.5 3 0 0 3 3 3 0 AAA domain MSA-2c PF12238.8 OQR95763.1 - 0.08 12.9 0.1 0.31 11.0 0.1 2.0 1 0 0 1 1 1 0 Merozoite surface antigen 2c Methyltransf_11 PF08241.12 OQR95763.1 - 0.13 12.9 0.2 0.68 10.6 0.1 2.2 2 0 0 2 2 1 0 Methyltransferase domain Zeta_toxin PF06414.12 OQR95763.1 - 0.14 11.4 0.2 8.4 5.6 0.0 3.0 3 0 0 3 3 3 0 Zeta toxin NTPase_1 PF03266.15 OQR95763.1 - 0.85 9.5 3.5 0.75 9.7 0.1 2.8 3 0 0 3 3 3 0 NTPase 60KD_IMP PF02096.20 OQR95764.1 - 2.2e-33 115.5 2.0 3e-33 115.1 2.0 1.2 1 0 0 1 1 1 1 60Kd inner membrane protein NIF PF03031.18 OQR95766.1 - 5.8e-24 84.6 0.6 8.5e-24 84.1 0.6 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase ubiquitin PF00240.23 OQR95766.1 - 0.0032 17.2 0.0 0.0066 16.2 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family Actin PF00022.19 OQR95767.1 - 8.4e-61 205.8 0.0 8.8e-60 202.4 0.0 1.9 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.13 OQR95767.1 - 0.00016 20.6 0.0 0.0053 15.6 0.0 2.3 2 0 0 2 2 2 2 MreB/Mbl protein FtsA PF14450.6 OQR95767.1 - 0.0044 17.4 0.0 0.039 14.4 0.0 2.4 2 1 0 2 2 2 1 Cell division protein FtsA WD40 PF00400.32 OQR95769.1 - 1.8e-20 72.8 8.2 4e-05 24.3 1.2 5.5 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OQR95769.1 - 1.2e-17 64.0 0.0 0.00012 22.3 0.0 5.2 3 1 2 5 5 5 5 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 OQR95769.1 - 6.2e-06 25.4 0.1 0.00013 21.1 0.0 2.8 2 1 1 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 OQR95769.1 - 0.0003 19.6 0.0 4.1 5.9 0.0 3.1 1 1 1 3 3 3 3 Nucleoporin Nup120/160 WD40_like PF17005.5 OQR95769.1 - 0.0042 16.5 0.0 0.26 10.6 0.0 3.0 2 1 0 2 2 2 1 WD40-like domain eIF2A PF08662.11 OQR95769.1 - 0.016 15.1 0.0 1.7 8.5 0.0 3.3 3 1 1 4 4 4 0 Eukaryotic translation initiation factor eIF2A CxC6 PF18721.1 OQR95772.1 - 3.1 8.1 14.2 85 3.5 14.2 2.6 1 1 0 1 1 1 0 CxC6 like cysteine cluster associated with KDZ transposases Ufd2P_core PF10408.9 OQR95774.1 - 2.1e-16 59.7 0.0 2.1e-16 59.7 0.0 2.1 2 1 0 2 2 2 1 Ubiquitin elongating factor core ZZ PF00569.17 OQR95774.1 - 8e-12 44.8 9.6 8e-12 44.8 9.6 3.5 3 0 0 3 3 3 2 Zinc finger, ZZ type C1_2 PF03107.16 OQR95774.1 - 2.5e-06 27.7 35.0 5.9e-05 23.3 4.2 3.6 3 0 0 3 3 3 3 C1 domain DMPK_coil PF08826.10 OQR95774.1 - 0.016 15.3 2.2 0.016 15.3 2.2 3.5 2 2 1 3 3 3 0 DMPK coiled coil domain like TSC22 PF01166.18 OQR95774.1 - 0.86 10.0 6.3 5.7 7.3 0.4 3.6 3 0 0 3 3 3 0 TSC-22/dip/bun family bZIP_1 PF00170.21 OQR95774.1 - 2.8 8.1 11.2 0.78 9.9 1.3 3.6 3 0 0 3 3 3 0 bZIP transcription factor Cob_adeno_trans PF01923.18 OQR95774.1 - 7.9 6.6 10.9 6.8 6.8 1.1 3.2 3 0 0 3 3 3 0 Cobalamin adenosyltransferase Pkinase PF00069.25 OQR95776.1 - 1.7e-23 83.3 1.5 9e-16 58.0 0.0 2.5 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OQR95776.1 - 1.2e-06 28.0 0.0 0.0074 15.6 0.0 2.5 2 0 0 2 2 2 2 Protein tyrosine kinase MAS20 PF02064.15 OQR95776.1 - 0.18 11.9 5.6 0.4 10.8 5.1 1.8 2 0 0 2 2 2 0 MAS20 protein import receptor NARP1 PF12569.8 OQR95776.1 - 0.2 10.5 9.5 0.3 9.9 9.5 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Glycoprotein_G PF00802.19 OQR95776.1 - 0.43 9.9 7.3 0.81 9.0 7.3 1.4 1 0 0 1 1 1 0 Pneumovirus attachment glycoprotein G ZZ PF00569.17 OQR95778.1 - 4.6e-31 106.4 27.9 2.8e-11 43.1 0.1 5.3 5 0 0 5 5 5 5 Zinc finger, ZZ type PH PF00169.29 OQR95778.1 - 2.2e-11 44.2 0.1 5e-11 43.1 0.1 1.6 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 OQR95778.1 - 0.00029 21.2 1.0 0.011 16.1 1.0 2.7 1 1 0 1 1 1 1 Pleckstrin homology domain FhuF_C PF11575.8 OQR95778.1 - 0.23 11.4 2.7 51 3.9 0.0 4.4 4 0 0 4 4 4 0 FhuF 2Fe-2S C-terminal domain Mito_carr PF00153.27 OQR95780.1 - 2.4e-53 178.0 6.2 2.1e-21 75.6 0.1 4.0 3 1 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 OQR95780.1 - 0.00025 20.3 1.1 0.0041 16.3 0.1 2.4 2 1 0 2 2 2 1 Gammaproteobacterial serine protease PsbX PF06596.11 OQR95780.1 - 0.041 13.9 0.9 0.12 12.4 0.9 1.8 1 0 0 1 1 1 0 Photosystem II reaction centre X protein (PsbX) Ank_2 PF12796.7 OQR95781.1 - 2.8e-07 31.0 1.0 5e-07 30.2 0.5 1.6 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank PF00023.30 OQR95781.1 - 1e-05 25.7 7.2 0.0051 17.2 1.1 2.6 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 OQR95781.1 - 0.00061 20.0 0.7 0.033 14.5 0.1 2.4 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQR95781.1 - 0.0021 18.4 1.6 0.42 11.3 0.1 2.7 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.6 OQR95781.1 - 0.051 14.2 0.0 0.098 13.3 0.0 1.7 1 1 0 1 1 1 0 Ankyrin repeats (many copies) MCU PF04678.13 OQR95782.1 - 1.4e-31 109.9 0.1 2.2e-31 109.3 0.1 1.3 1 0 0 1 1 1 1 Mitochondrial calcium uniporter COR PF16095.5 OQR95782.1 - 1.6e-08 34.6 0.1 3e-08 33.7 0.0 1.5 1 1 0 1 1 1 1 C-terminal of Roc, COR, domain TRP PF06011.12 OQR95785.1 - 3.9e-09 35.8 33.3 1.9e-08 33.5 33.3 2.0 1 1 0 1 1 1 1 Transient receptor potential (TRP) ion channel Phage_holin_3_6 PF07332.11 OQR95785.1 - 0.0042 17.1 0.3 0.0042 17.1 0.3 4.7 4 1 0 5 5 5 1 Putative Actinobacterial Holin-X, holin superfamily III DUF4806 PF16064.5 OQR95786.1 - 0.069 13.4 0.1 0.11 12.9 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4806) PDZ_1 PF12812.7 OQR95789.1 - 5.9e-09 35.8 0.0 2.5e-08 33.8 0.0 2.1 2 0 0 2 2 2 1 PDZ-like domain PDZ_2 PF13180.6 OQR95789.1 - 3.4e-08 33.7 0.0 0.00071 19.8 0.0 2.8 2 0 0 2 2 2 2 PDZ domain PDZ_6 PF17820.1 OQR95789.1 - 4.1e-07 29.7 0.1 0.051 13.4 0.0 3.4 3 0 0 3 3 3 2 PDZ domain PDZ PF00595.24 OQR95789.1 - 1.9e-05 24.9 0.0 0.012 15.9 0.0 3.2 3 0 0 3 3 3 1 PDZ domain Tricorn_PDZ PF14685.6 OQR95789.1 - 0.082 12.9 0.0 2.6 8.1 0.0 2.5 2 0 0 2 2 2 0 Tricorn protease PDZ domain 7tm_3 PF00003.22 OQR95790.1 - 3.2e-36 125.3 25.8 6e-36 124.4 25.8 1.4 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR PAN_3 PF08277.12 OQR95790.1 - 0.12 12.2 1.8 0.28 11.0 1.8 1.6 1 0 0 1 1 1 0 PAN-like domain DUF4131 PF13567.6 OQR95790.1 - 2.8 7.5 9.7 4.9 6.8 3.3 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) RCC1 PF00415.18 OQR95791.1 - 2.9e-66 219.9 15.7 2.1e-12 47.5 0.2 7.7 7 1 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 OQR95791.1 - 1.4e-26 91.7 40.7 1.4e-05 24.7 0.3 7.9 8 0 0 8 8 8 7 Regulator of chromosome condensation (RCC1) repeat SecY PF00344.20 OQR95792.1 - 3e-68 230.3 17.3 3.8e-68 230.0 17.3 1.1 1 0 0 1 1 1 1 SecY translocase Plug_translocon PF10559.9 OQR95792.1 - 2e-13 49.9 0.9 6.5e-13 48.3 0.1 2.3 2 0 0 2 2 2 1 Plug domain of Sec61p Glyco_hydro_63N PF16923.5 OQR95793.1 - 0.061 13.4 0.0 0.14 12.2 0.0 1.5 1 0 0 1 1 1 0 Glycosyl hydrolase family 63 N-terminal domain bVLRF1 PF18826.1 OQR95794.1 - 1.1e-51 174.6 0.0 3.4e-51 173.0 0.0 1.8 1 0 0 1 1 1 1 bacteroidetes VLRF1 release factor VATC PF18716.1 OQR95794.1 - 1.3e-08 34.5 0.7 1.3e-08 34.5 0.7 2.5 3 0 0 3 3 3 1 Vms1-associating treble clef domain Ank_2 PF12796.7 OQR95794.1 - 5.5e-08 33.3 0.0 1.2e-07 32.2 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OQR95794.1 - 0.00022 21.4 0.5 0.14 12.8 0.2 2.6 2 0 0 2 2 2 1 Ankyrin repeat Ank_5 PF13857.6 OQR95794.1 - 0.00051 20.3 0.4 0.003 17.9 0.2 2.3 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.30 OQR95794.1 - 0.00055 20.3 0.8 0.012 16.0 0.1 2.6 2 0 0 2 2 2 1 Ankyrin repeat AKAP95 PF04988.12 OQR95794.1 - 0.0029 17.9 8.3 0.0033 17.7 0.7 2.3 2 0 0 2 2 2 1 A-kinase anchoring protein 95 (AKAP95) Ank_4 PF13637.6 OQR95794.1 - 0.014 15.9 0.2 0.43 11.2 0.1 2.4 1 1 0 2 2 2 0 Ankyrin repeats (many copies) acVLRF1 PF18859.1 OQR95794.1 - 0.058 13.7 0.5 0.058 13.7 0.5 2.3 3 0 0 3 3 3 0 Actinobacteria/chloroflexi VLRF1 release factor zf-FCS PF06467.14 OQR95794.1 - 0.15 12.0 2.2 5.5 7.0 0.1 2.8 2 0 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif DUF3464 PF11947.8 OQR95794.1 - 0.24 11.1 2.5 0.71 9.6 2.5 1.8 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 GvpL_GvpF PF06386.11 OQR95794.1 - 5 7.0 10.3 2 8.3 6.7 2.0 2 0 0 2 2 2 0 Gas vesicle synthesis protein GvpL/GvpF zf-MYND PF01753.18 OQR95794.1 - 5.2 7.2 6.0 1.1 9.4 2.1 2.0 2 0 0 2 2 1 0 MYND finger Rrn6 PF10214.9 OQR95794.1 - 8.5 4.7 8.5 9.4 4.6 5.4 2.0 2 0 0 2 2 2 0 RNA polymerase I-specific transcription-initiation factor FYVE PF01363.21 OQR95795.1 - 2e-14 53.4 2.7 4e-14 52.5 2.7 1.5 1 0 0 1 1 1 1 FYVE zinc finger GAF PF01590.26 OQR95795.1 - 6.7e-07 30.0 0.0 1.2e-06 29.2 0.0 1.4 1 0 0 1 1 1 1 GAF domain GAF_3 PF13492.6 OQR95795.1 - 0.00042 20.7 0.0 0.00083 19.7 0.0 1.5 1 0 0 1 1 1 1 GAF domain FYVE_2 PF02318.16 OQR95795.1 - 0.0022 18.2 3.0 0.0052 17.0 2.2 1.8 2 0 0 2 2 2 1 FYVE-type zinc finger SpoVT_C PF15714.5 OQR95795.1 - 0.015 15.3 0.0 0.046 13.8 0.0 1.8 2 0 0 2 2 2 0 Stage V sporulation protein T C-terminal, transcription factor KASH_CCD PF14662.6 OQR95796.1 - 0.00076 19.4 4.8 0.0012 18.7 4.8 1.2 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 or KASH CCDC24 PF15669.5 OQR95796.1 - 0.0096 15.8 0.5 0.016 15.1 0.5 1.3 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 24 family Bowman-Birk_leg PF00228.20 OQR95796.1 - 0.093 13.2 1.9 0.21 12.0 1.9 1.7 1 0 0 1 1 1 0 Bowman-Birk serine protease inhibitor family Uso1_p115_C PF04871.13 OQR95796.1 - 0.55 10.6 4.4 0.92 9.9 4.4 1.3 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region bZIP_1 PF00170.21 OQR95796.1 - 0.78 9.9 8.1 1.9 8.7 8.1 1.6 1 0 0 1 1 1 0 bZIP transcription factor AAA_13 PF13166.6 OQR95796.1 - 0.81 8.3 2.5 1.1 7.8 2.5 1.1 1 0 0 1 1 1 0 AAA domain RINGv PF12906.7 OQR95797.1 - 6.3e-11 42.2 3.8 1.3e-10 41.2 3.8 1.6 1 0 0 1 1 1 1 RING-variant domain DUF179 PF02622.15 OQR95797.1 - 6.4e-06 26.2 0.0 2.3e-05 24.4 0.0 1.9 1 1 0 1 1 1 1 Uncharacterized ACR, COG1678 FKBP_C PF00254.28 OQR95799.1 - 3.4e-22 78.6 0.0 5.7e-22 77.8 0.0 1.3 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase DUF2569 PF10754.9 OQR95799.1 - 0.062 13.7 4.7 1.5 9.3 0.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2569) DUF4131 PF13567.6 OQR95799.1 - 0.87 9.2 6.4 33 4.1 6.1 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) DUF4203 PF13886.6 OQR95799.1 - 1.7 8.3 20.5 8.4 6.0 20.5 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4203) Pkinase_Tyr PF07714.17 OQR95802.1 - 6.3e-11 42.1 0.1 0.00016 21.0 0.0 2.1 1 1 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 OQR95802.1 - 7.7e-11 41.8 0.0 1.3e-05 24.7 0.0 2.1 1 1 1 2 2 2 2 Protein kinase domain GST_C PF00043.25 OQR95802.1 - 0.13 12.5 0.0 0.22 11.7 0.0 1.3 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain NUC173 PF08161.12 OQR95803.1 - 4e-48 163.8 0.2 4e-48 163.8 0.2 4.2 6 0 0 6 6 6 1 NUC173 domain RhoGAP PF00620.27 OQR95803.1 - 0.077 12.8 0.5 0.45 10.3 0.2 2.5 2 0 0 2 2 2 0 RhoGAP domain HEAT PF02985.22 OQR95803.1 - 0.086 13.1 3.7 30 5.3 0.0 5.9 6 0 0 6 6 6 0 HEAT repeat Vps35 PF03635.17 OQR95803.1 - 0.24 9.9 8.1 0.39 9.2 0.6 2.3 2 0 0 2 2 2 0 Vacuolar protein sorting-associated protein 35 UME PF08064.13 OQR95803.1 - 0.3 11.0 13.0 1.6 8.7 0.1 4.8 5 2 0 5 5 5 0 UME (NUC010) domain DUF3605 PF12239.8 OQR95805.1 - 0.0066 16.8 3.1 0.018 15.4 3.1 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF3605) PAS_4 PF08448.10 OQR95805.1 - 0.02 15.1 0.3 0.93 9.8 0.1 2.2 1 1 1 2 2 2 0 PAS fold MS_channel PF00924.18 OQR95806.1 - 2.2e-18 66.6 1.7 3.9e-18 65.8 1.7 1.3 1 0 0 1 1 1 1 Mechanosensitive ion channel PX PF00787.24 OQR95808.1 - 6.3e-06 26.2 0.4 1.2e-05 25.3 0.4 1.5 1 1 0 1 1 1 1 PX domain Ank_2 PF12796.7 OQR95812.1 - 1.9e-50 169.4 27.8 3.7e-18 65.9 1.0 5.0 1 1 5 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQR95812.1 - 4.1e-35 119.7 2.2 4.5e-09 36.7 0.0 7.1 2 1 4 7 7 7 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQR95812.1 - 1.7e-31 104.7 13.7 0.00012 22.2 0.1 10.0 9 1 1 10 10 10 7 Ankyrin repeat Ank_5 PF13857.6 OQR95812.1 - 1.9e-29 101.3 14.3 4.7e-07 30.0 0.4 8.1 2 2 6 8 8 8 7 Ankyrin repeats (many copies) Ank PF00023.30 OQR95812.1 - 2e-23 81.8 19.0 0.00059 20.2 0.0 9.1 10 0 0 10 10 10 5 Ankyrin repeat Pkinase_Tyr PF07714.17 OQR95812.1 - 5.7e-12 45.5 0.0 1e-11 44.7 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OQR95812.1 - 1.4e-10 41.0 0.0 2.6e-10 40.1 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain RPAP1_C PF08620.10 OQR95813.1 - 8.4e-23 80.3 0.0 2e-22 79.0 0.0 1.7 1 0 0 1 1 1 1 RPAP1-like, C-terminal RPAP1_N PF08621.10 OQR95813.1 - 4.6e-13 48.7 1.9 1.3e-12 47.3 1.9 1.8 1 0 0 1 1 1 1 RPAP1-like, N-terminal MFS_1 PF07690.16 OQR95814.1 - 1.4e-10 40.7 39.1 1.2e-06 27.7 25.3 2.7 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 OQR95814.1 - 0.0039 16.1 9.2 0.0039 16.1 9.2 2.5 3 0 0 3 3 3 1 Sugar (and other) transporter BTP PF05232.12 OQR95814.1 - 2.1 8.5 7.2 2.2 8.4 0.1 3.2 1 1 1 2 2 2 0 Chlorhexidine efflux transporter TPR_12 PF13424.6 OQR95815.1 - 1.1e-29 102.5 0.1 4.4e-12 46.1 0.1 4.8 3 1 2 5 5 5 5 Tetratricopeptide repeat TPR_10 PF13374.6 OQR95815.1 - 2e-18 65.6 0.0 5.8e-05 22.8 0.0 5.6 5 0 0 5 5 5 3 Tetratricopeptide repeat zf-met2 PF12907.7 OQR95815.1 - 1.8e-13 50.3 1.6 4.3e-13 49.2 1.6 1.7 1 0 0 1 1 1 1 Zinc-binding TPR_1 PF00515.28 OQR95815.1 - 6.6e-07 28.9 7.7 0.096 12.6 0.1 5.4 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_2 PF07719.17 OQR95815.1 - 1.8e-06 27.6 9.6 0.3 11.3 0.0 5.5 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_7 PF13176.6 OQR95815.1 - 0.00026 20.8 0.0 0.4 10.8 0.0 4.4 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_MalT PF17874.1 OQR95815.1 - 0.026 13.9 0.0 0.057 12.8 0.0 1.5 1 0 0 1 1 1 0 MalT-like TPR region TPR_8 PF13181.6 OQR95815.1 - 0.048 13.9 2.6 0.93 9.9 0.0 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat MtN3_slv PF03083.16 OQR95817.1 - 2.2e-25 88.5 11.8 6e-15 55.1 3.0 2.7 2 0 0 2 2 2 2 Sugar efflux transporter for intercellular exchange Spc7 PF08317.11 OQR95818.1 - 1e-05 24.6 39.6 0.011 14.7 12.9 2.9 1 1 1 2 2 2 2 Spc7 kinetochore protein Fez1 PF06818.15 OQR95818.1 - 0.00017 22.1 18.4 0.00017 22.1 18.4 2.2 1 1 1 2 2 2 1 Fez1 Golgin_A5 PF09787.9 OQR95818.1 - 0.00076 19.0 35.9 0.0056 16.2 21.1 2.3 1 1 1 2 2 2 2 Golgin subfamily A member 5 ERM PF00769.19 OQR95818.1 - 0.00093 19.1 44.0 0.0013 18.6 25.4 2.5 2 1 1 3 3 2 1 Ezrin/radixin/moesin family COMM_domain PF07258.14 OQR95818.1 - 0.0028 17.7 7.2 0.14 12.3 4.0 3.3 2 1 0 2 2 2 1 COMM domain HMMR_N PF15905.5 OQR95818.1 - 0.012 15.1 38.5 0.017 14.6 24.6 2.7 1 1 2 3 3 3 0 Hyaluronan mediated motility receptor N-terminal TPR_MLP1_2 PF07926.12 OQR95818.1 - 0.015 15.4 40.0 0.17 12.0 22.6 4.3 2 1 2 4 4 4 0 TPR/MLP1/MLP2-like protein ZapB PF06005.12 OQR95818.1 - 0.02 15.3 7.4 0.02 15.3 7.4 6.3 3 2 3 6 6 6 0 Cell division protein ZapB Tup_N PF08581.10 OQR95818.1 - 0.024 14.9 28.0 0.04 14.2 6.1 4.8 5 0 0 5 5 5 0 Tup N-terminal Peptidase_M61 PF05299.12 OQR95818.1 - 0.046 14.1 1.1 0.046 14.1 1.1 2.8 1 1 3 4 4 4 0 M61 glycyl aminopeptidase APG6_N PF17675.1 OQR95818.1 - 0.058 13.9 46.3 0.21 12.1 20.0 3.6 1 1 3 4 4 4 0 Apg6 coiled-coil region FlaC_arch PF05377.11 OQR95818.1 - 0.12 12.8 20.7 0.6 10.5 4.4 4.9 3 2 1 4 4 4 0 Flagella accessory protein C (FlaC) DUF3450 PF11932.8 OQR95818.1 - 0.13 11.5 32.1 0.31 10.3 2.2 3.6 1 1 2 3 3 3 0 Protein of unknown function (DUF3450) Fib_alpha PF08702.10 OQR95818.1 - 0.19 11.9 24.8 0.35 11.1 12.5 3.8 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family SOGA PF11365.8 OQR95818.1 - 0.25 12.5 29.7 0.093 13.9 8.1 3.8 1 1 3 4 4 4 0 Protein SOGA CENP-F_leu_zip PF10473.9 OQR95818.1 - 0.3 11.1 40.1 0.19 11.7 13.7 3.6 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 COG5 PF10392.9 OQR95818.1 - 0.31 11.2 17.7 0.12 12.6 6.2 3.0 2 2 1 3 3 3 0 Golgi transport complex subunit 5 DUF4618 PF15397.6 OQR95818.1 - 0.32 10.4 30.3 2.1 7.7 12.1 3.8 1 1 2 3 3 3 0 Domain of unknown function (DUF4618) Occludin_ELL PF07303.13 OQR95818.1 - 0.32 11.8 21.6 6.2 7.6 1.9 4.4 1 1 4 5 5 5 0 Occludin homology domain MAD PF05557.13 OQR95818.1 - 0.4 9.0 37.6 0.11 10.8 33.3 2.0 1 1 1 2 2 2 0 Mitotic checkpoint protein MtrG PF04210.13 OQR95818.1 - 0.5 10.2 4.8 2.7 7.9 0.1 3.4 3 0 0 3 3 2 0 Tetrahydromethanopterin S-methyltransferase, subunit G ATG16 PF08614.11 OQR95818.1 - 0.59 10.3 44.1 0.054 13.7 11.8 3.4 2 1 1 3 3 2 0 Autophagy protein 16 (ATG16) UPF0242 PF06785.11 OQR95818.1 - 0.8 9.8 36.1 1.2 9.2 18.9 3.6 2 1 1 3 3 3 0 Uncharacterised protein family (UPF0242) N-terminus Prefoldin PF02996.17 OQR95818.1 - 0.8 9.6 27.5 0.099 12.6 12.3 4.1 1 1 2 3 3 3 0 Prefoldin subunit ING PF12998.7 OQR95818.1 - 0.83 10.3 16.9 2 9.1 5.4 3.2 2 1 0 3 3 3 0 Inhibitor of growth proteins N-terminal histone-binding BRE1 PF08647.11 OQR95818.1 - 0.89 9.7 38.5 0.13 12.3 3.5 4.6 2 1 1 4 4 3 0 BRE1 E3 ubiquitin ligase V-SNARE PF05008.15 OQR95818.1 - 1.1 9.7 29.5 0.17 12.2 7.8 5.1 2 1 1 4 4 4 0 Vesicle transport v-SNARE protein N-terminus HrpB7 PF09486.10 OQR95818.1 - 1.2 9.5 27.5 0.91 9.9 7.3 3.6 1 1 3 4 4 4 0 Bacterial type III secretion protein (HrpB7) Rootletin PF15035.6 OQR95818.1 - 1.3 9.0 35.1 0.34 10.9 16.7 2.6 1 1 1 2 2 2 0 Ciliary rootlet component, centrosome cohesion DUF1664 PF07889.12 OQR95818.1 - 1.5 8.9 21.9 4.8 7.2 0.5 4.2 1 1 3 4 4 4 0 Protein of unknown function (DUF1664) Leu_zip PF15294.6 OQR95818.1 - 1.9 7.9 33.7 1.2 8.6 27.3 2.4 1 1 1 2 2 2 0 Leucine zipper ABC_tran_CTD PF16326.5 OQR95818.1 - 2.3 8.6 38.0 2.5 8.4 4.4 5.0 1 1 3 4 4 4 0 ABC transporter C-terminal domain DUF5082 PF16888.5 OQR95818.1 - 2.4 8.5 29.5 2.1 8.6 1.9 4.3 1 1 2 4 4 4 0 Domain of unknown function (DUF5082) Bacillus_HBL PF05791.11 OQR95818.1 - 2.4 7.9 19.6 0.13 12.1 10.0 2.6 2 1 1 3 3 2 0 Bacillus haemolytic enterotoxin (HBL) Syntaxin_2 PF14523.6 OQR95818.1 - 2.6 8.4 21.2 0.22 11.9 8.3 3.4 2 1 1 3 3 3 0 Syntaxin-like protein CENP-H PF05837.12 OQR95818.1 - 2.7 8.5 35.8 1.1 9.7 14.1 3.6 2 1 2 4 4 3 0 Centromere protein H (CENP-H) V_ATPase_I PF01496.19 OQR95818.1 - 3.5 5.4 27.1 1.2e+03 -3.0 26.9 2.5 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family Atg14 PF10186.9 OQR95818.1 - 3.7 6.5 27.8 22 4.0 3.4 2.3 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 Lebercilin PF15619.6 OQR95818.1 - 5.2 6.7 41.9 2.2 7.9 23.0 4.2 2 1 1 3 3 3 0 Ciliary protein causing Leber congenital amaurosis disease AAA_13 PF13166.6 OQR95818.1 - 5.7 5.4 32.3 2.8 6.5 28.4 1.9 1 1 1 2 2 2 0 AAA domain CALCOCO1 PF07888.11 OQR95818.1 - 7.8 5.2 40.4 0.076 11.9 5.4 2.7 1 1 1 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like DUF3584 PF12128.8 OQR95818.1 - 8.3 3.8 35.1 0.22 9.0 12.4 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF3584) DUF16 PF01519.16 OQR95818.1 - 8.4 6.9 30.0 4.8 7.7 10.4 4.3 2 1 2 4 4 4 0 Protein of unknown function DUF16 LPP PF04728.13 OQR95818.1 - 8.7 6.8 22.8 0.98 9.9 1.5 4.9 4 1 1 5 5 4 0 Lipoprotein leucine-zipper DUF948 PF06103.11 OQR95818.1 - 9.4 6.6 13.3 8 6.8 5.8 3.3 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) Bcr-Abl_Oligo PF09036.10 OQR95818.1 - 9.7 6.3 9.0 1.2 9.2 1.2 3.3 2 1 0 2 2 2 0 Bcr-Abl oncoprotein oligomerisation domain LicD PF04991.13 OQR95820.1 - 1.8e-19 70.8 0.4 1.9e-18 67.5 0.4 2.4 1 1 0 1 1 1 1 LicD family LicD PF04991.13 OQR95821.1 - 2.8e-17 63.6 0.2 3e-16 60.2 0.2 2.2 1 1 0 1 1 1 1 LicD family PBCV_basic_adap PF08789.10 OQR95821.1 - 0.12 12.5 0.1 0.23 11.6 0.1 1.4 1 0 0 1 1 1 0 PBCV-specific basic adaptor domain DHO_dh PF01180.21 OQR95822.1 - 5.6e-51 173.5 0.0 6.6e-51 173.3 0.0 1.1 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase FMN_dh PF01070.18 OQR95822.1 - 0.00013 21.2 0.0 0.00023 20.3 0.0 1.4 1 0 0 1 1 1 1 FMN-dependent dehydrogenase NMO PF03060.15 OQR95822.1 - 0.00013 21.5 0.1 0.00022 20.8 0.1 1.3 1 0 0 1 1 1 1 Nitronate monooxygenase Glu_synthase PF01645.17 OQR95822.1 - 0.015 14.5 0.0 0.026 13.6 0.0 1.3 1 0 0 1 1 1 0 Conserved region in glutamate synthase His_biosynth PF00977.21 OQR95822.1 - 0.017 14.6 0.0 0.032 13.7 0.0 1.4 1 1 0 1 1 1 0 Histidine biosynthesis protein Dus PF01207.17 OQR95822.1 - 0.031 13.4 0.5 1.1 8.2 0.1 2.2 2 0 0 2 2 2 0 Dihydrouridine synthase (Dus) IMPDH PF00478.25 OQR95822.1 - 0.083 11.9 0.2 0.25 10.3 0.2 1.6 1 1 0 1 1 1 0 IMP dehydrogenase / GMP reductase domain She9_MDM33 PF05546.11 OQR95822.1 - 0.21 11.4 0.2 0.31 10.8 0.2 1.2 1 0 0 1 1 1 0 She9 / Mdm33 family Peptidase_C1 PF00112.23 OQR95823.1 - 1.2e-58 198.7 7.3 1.2e-58 198.7 7.3 2.4 2 1 0 2 2 2 1 Papain family cysteine protease PAN_4 PF14295.6 OQR95823.1 - 9.2e-23 79.9 29.7 8.4e-10 38.4 3.9 4.5 3 0 0 3 3 3 3 PAN domain PAN_1 PF00024.26 OQR95823.1 - 3.2e-17 62.2 19.8 1.6e-07 31.2 0.5 3.8 1 1 2 3 3 3 3 PAN domain Peptidase_C1_2 PF03051.15 OQR95823.1 - 0.0029 16.5 6.1 0.03 13.1 0.1 2.4 3 0 0 3 3 3 2 Peptidase C1-like family Inhibitor_I29 PF08246.12 OQR95823.1 - 0.018 15.5 0.1 0.036 14.5 0.1 1.5 1 0 0 1 1 1 0 Cathepsin propeptide inhibitor domain (I29) PAN_2 PF08276.11 OQR95823.1 - 5.5 7.2 39.4 0.78 9.9 3.2 4.8 5 0 0 5 5 5 0 PAN-like domain E1-E2_ATPase PF00122.20 OQR95825.1 - 1.4e-54 184.4 1.9 7.3e-54 182.0 1.9 2.4 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 OQR95825.1 - 4.1e-48 163.5 1.6 4.1e-48 163.5 1.6 3.7 4 0 0 4 4 4 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 OQR95825.1 - 1.5e-21 77.7 2.5 3.7e-21 76.4 2.5 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 OQR95825.1 - 2.3e-15 56.4 0.1 5.5e-15 55.2 0.1 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 OQR95825.1 - 3.4e-09 36.3 0.0 9.4e-09 34.8 0.0 1.8 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 OQR95825.1 - 0.0014 18.4 1.5 0.0026 17.6 1.5 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Pkinase_Tyr PF07714.17 OQR95826.1 - 2.8e-55 187.4 0.0 3.2e-55 187.2 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OQR95826.1 - 2.9e-40 138.3 0.0 3.8e-40 137.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 OQR95826.1 - 0.0014 17.5 0.0 0.002 17.0 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 OQR95826.1 - 0.02 14.2 0.0 0.031 13.6 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 OQR95826.1 - 0.041 13.2 0.0 0.061 12.6 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Haspin_kinase PF12330.8 OQR95826.1 - 0.21 10.5 0.0 0.71 8.8 0.0 1.9 1 1 0 1 1 1 0 Haspin like kinase domain VacA PF02691.15 OQR95826.1 - 0.25 9.2 0.0 0.31 8.9 0.0 1.0 1 0 0 1 1 1 0 Vacuolating cyotoxin Topoisom_I PF01028.20 OQR95827.1 - 1.5e-92 309.0 2.9 1.5e-92 309.0 2.9 2.3 2 0 0 2 2 2 1 Eukaryotic DNA topoisomerase I, catalytic core Topoisom_I_N PF02919.15 OQR95827.1 - 1.1e-84 283.2 0.2 1.1e-84 283.2 0.2 3.5 3 0 0 3 3 3 1 Eukaryotic DNA topoisomerase I, DNA binding fragment Topo_C_assoc PF14370.6 OQR95827.1 - 1.1e-30 105.4 0.7 1.1e-30 105.4 0.7 2.8 2 0 0 2 2 2 1 C-terminal topoisomerase domain NPV_P10 PF05531.12 OQR95827.1 - 1.4 9.4 4.5 27 5.3 0.8 2.9 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Syntaxin-6_N PF09177.11 OQR95827.1 - 3.2 8.4 13.0 0.095 13.3 0.7 3.2 2 1 0 2 2 2 0 Syntaxin 6, N-terminal MFS_3 PF05977.13 OQR95828.1 - 0.026 12.9 0.3 0.079 11.3 0.0 1.7 2 0 0 2 2 2 0 Transmembrane secretion effector BT1 PF03092.16 OQR95831.1 - 4.7e-67 226.4 18.7 2.4e-37 128.4 8.8 2.3 1 1 0 2 2 2 2 BT1 family HORMA PF02301.18 OQR95831.1 - 1.4e-18 67.2 0.0 2.8e-18 66.3 0.0 1.5 1 1 0 1 1 1 1 HORMA domain Med11 PF10280.9 OQR95832.1 - 0.012 16.1 0.1 0.02 15.4 0.1 1.3 1 0 0 1 1 1 0 Mediator complex protein Imm53 PF15580.6 OQR95832.1 - 0.12 12.1 1.0 14 5.5 0.3 2.7 2 0 0 2 2 2 0 Immunity protein 53 DUF5578 PF17741.1 OQR95833.1 - 5.6e-31 107.9 0.5 8.3e-31 107.4 0.5 1.3 1 0 0 1 1 1 1 Family of unknown function (DUF5578) DUF87 PF01935.17 OQR95833.1 - 0.11 12.6 0.1 1.6 8.8 0.0 2.1 2 0 0 2 2 2 0 Helicase HerA, central domain Aldedh PF00171.22 OQR95834.1 - 1.9e-156 521.2 0.4 2.1e-156 521.1 0.4 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF4880 PF16220.5 OQR95834.1 - 0.017 15.0 0.4 0.043 13.7 0.4 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4880) DUF1487 PF07368.11 OQR95834.1 - 0.17 11.3 0.0 0.32 10.4 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1487) Ank_2 PF12796.7 OQR95835.1 - 4.6e-19 68.8 0.1 3e-08 34.2 0.0 3.2 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQR95835.1 - 4.6e-15 55.8 4.7 4.6e-07 30.2 0.2 3.0 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 OQR95835.1 - 2.1e-14 53.2 0.9 0.00018 21.8 0.1 4.2 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.6 OQR95835.1 - 4.4e-13 49.2 0.1 0.00033 20.9 0.1 4.0 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQR95835.1 - 7.2e-13 47.5 0.4 0.0096 16.4 0.0 4.4 4 0 0 4 4 4 3 Ankyrin repeat HOIP-UBA PF16678.5 OQR95835.1 - 0.0057 16.7 0.1 0.063 13.3 0.1 2.7 2 0 0 2 2 2 1 HOIP UBA domain pair Na_H_Exchanger PF00999.21 OQR95836.1 - 7.2e-69 232.4 31.4 8.7e-69 232.1 31.4 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family GPI-anchored PF10342.9 OQR95837.1 - 0.00026 21.7 0.0 0.00038 21.1 0.0 1.3 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DAO PF01266.24 OQR95838.1 - 4.8e-39 134.9 0.1 5.5e-39 134.7 0.1 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 OQR95838.1 - 0.0096 15.2 0.0 0.022 14.0 0.0 1.7 2 0 0 2 2 2 1 FAD binding domain FAD_binding_2 PF00890.24 OQR95838.1 - 0.022 13.8 0.1 0.035 13.2 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain NAD_binding_7 PF13241.6 OQR95838.1 - 0.035 14.5 0.0 0.11 12.9 0.0 1.9 2 0 0 2 2 2 0 Putative NAD(P)-binding Thi4 PF01946.17 OQR95838.1 - 0.043 13.0 0.8 0.11 11.7 0.5 1.8 2 0 0 2 2 2 0 Thi4 family Pyr_redox PF00070.27 OQR95838.1 - 0.045 14.3 0.3 0.38 11.4 0.2 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Sacchrp_dh_NADP PF03435.18 OQR95838.1 - 0.046 14.0 0.0 0.25 11.6 0.0 2.2 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain Pyr_redox_2 PF07992.14 OQR95838.1 - 0.058 12.6 0.0 0.11 11.7 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OQR95838.1 - 0.063 13.5 0.1 0.19 12.0 0.1 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain UDPG_MGDP_dh_N PF03721.14 OQR95838.1 - 0.069 12.7 0.0 0.15 11.6 0.0 1.7 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain ThiF PF00899.21 OQR95838.1 - 0.096 12.0 0.8 0.25 10.7 0.2 1.8 2 0 0 2 2 2 0 ThiF family bZIP_1 PF00170.21 OQR95839.1 - 0.43 10.7 13.0 0.72 10.0 13.0 1.4 1 0 0 1 1 1 0 bZIP transcription factor IQ PF00612.27 OQR95840.1 - 3.7e-28 94.6 56.8 0.00055 19.5 0.7 11.9 11 0 0 11 11 11 10 IQ calmodulin-binding motif WW PF00397.26 OQR95840.1 - 2e-23 82.1 42.0 6.2e-08 32.6 3.0 5.5 5 0 0 5 5 5 5 WW domain LRR_4 PF12799.7 OQR95840.1 - 3.4e-16 59.1 3.7 0.024 15.1 0.0 7.3 4 2 5 9 9 9 6 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 OQR95840.1 - 4.6e-09 35.6 18.9 0.51 10.5 0.0 10.5 12 0 0 12 12 12 3 Leucine Rich repeat LRR_1 PF00560.33 OQR95840.1 - 0.023 15.2 12.8 41 5.3 1.6 7.8 8 2 2 10 10 10 0 Leucine Rich Repeat PQQ PF01011.21 OQR95840.1 - 0.048 13.6 0.0 0.15 12.0 0.0 1.8 1 0 0 1 1 1 0 PQQ enzyme repeat Glyco_hyd_101C PF17451.2 OQR95840.1 - 0.09 13.1 11.8 1.8 8.9 0.2 4.3 4 1 0 4 4 4 0 Glycosyl hydrolase 101 beta sandwich domain FAD_binding_1 PF00667.20 OQR95841.1 - 1.3e-45 155.7 0.0 2e-45 155.1 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 OQR95841.1 - 2.5e-29 102.3 0.0 4.7e-29 101.4 0.0 1.5 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.21 OQR95841.1 - 3.1e-09 37.4 0.0 5.6e-09 36.6 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain SPC25 PF06703.11 OQR95842.1 - 2.1e-27 95.9 1.2 2.6e-27 95.6 1.2 1.1 1 0 0 1 1 1 1 Microsomal signal peptidase 25 kDa subunit (SPC25) Phage_holin_5_2 PF16079.5 OQR95842.1 - 0.17 12.3 0.9 0.31 11.4 0.9 1.4 1 0 0 1 1 1 0 Phage holin family Hol44, in holin superfamily V MAPEG PF01124.18 OQR95843.1 - 2.2e-16 59.9 1.0 2.9e-16 59.6 1.0 1.1 1 0 0 1 1 1 1 MAPEG family IgG_binding_B PF01378.17 OQR95843.1 - 0.0024 17.9 0.8 0.12 12.4 0.2 2.5 2 0 0 2 2 2 2 B domain AAA PF00004.29 OQR95844.1 - 1.3e-16 61.2 0.0 3.4e-15 56.6 0.0 2.6 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 OQR95844.1 - 1.1e-05 25.4 0.0 4.9e-05 23.4 0.0 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 OQR95844.1 - 2.6e-05 24.7 0.0 0.00019 21.9 0.0 2.2 1 1 0 1 1 1 1 AAA ATPase domain RuvB_N PF05496.12 OQR95844.1 - 0.0028 17.4 0.0 0.0068 16.2 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_11 PF13086.6 OQR95844.1 - 0.0043 16.9 0.0 0.0088 15.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 OQR95844.1 - 0.0067 16.2 0.0 0.013 15.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 OQR95844.1 - 0.0077 16.5 0.0 0.023 15.0 0.0 1.9 1 1 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 OQR95844.1 - 0.016 15.6 0.0 0.068 13.6 0.0 2.2 2 0 0 2 2 1 0 RNA helicase AAA_7 PF12775.7 OQR95844.1 - 0.022 14.3 0.0 0.062 12.8 0.0 1.7 1 0 0 1 1 1 0 P-loop containing dynein motor region DUF815 PF05673.13 OQR95844.1 - 0.027 13.6 0.0 0.075 12.2 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF815) KAP_NTPase PF07693.14 OQR95844.1 - 0.034 13.4 0.0 0.063 12.5 0.0 1.5 1 0 0 1 1 1 0 KAP family P-loop domain AAA_19 PF13245.6 OQR95844.1 - 0.04 14.2 0.1 0.11 12.8 0.1 1.7 1 0 0 1 1 1 0 AAA domain Bac_DnaA PF00308.18 OQR95844.1 - 0.056 13.3 0.1 0.17 11.7 0.0 1.9 2 0 0 2 2 2 0 Bacterial dnaA protein AAA_18 PF13238.6 OQR95844.1 - 0.069 13.7 0.0 0.22 12.1 0.0 1.9 1 1 0 1 1 1 0 AAA domain ATP_bind_1 PF03029.17 OQR95844.1 - 0.087 12.6 0.0 0.2 11.4 0.0 1.6 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein AAA_14 PF13173.6 OQR95844.1 - 0.12 12.4 0.0 0.72 9.9 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 OQR95844.1 - 0.13 12.4 0.0 0.36 11.0 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 OQR95844.1 - 0.13 12.5 0.0 0.38 11.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain FGGY_N PF00370.21 OQR95845.1 - 2.9e-72 243.2 0.2 4.2e-72 242.7 0.2 1.2 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain FGGY_C PF02782.16 OQR95845.1 - 4.2e-62 209.4 1.5 8.2e-62 208.5 1.5 1.5 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain BcrAD_BadFG PF01869.20 OQR95845.1 - 0.0004 20.0 0.7 0.087 12.3 0.0 2.8 3 0 0 3 3 3 2 BadF/BadG/BcrA/BcrD ATPase family ROK PF00480.20 OQR95845.1 - 0.085 12.3 0.1 0.19 11.1 0.0 1.6 2 0 0 2 2 2 0 ROK family DUF5626 PF18540.1 OQR95852.1 - 0.14 12.7 2.5 0.16 12.5 1.5 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF5626) WEMBL PF05701.11 OQR95853.1 - 0.0057 15.4 2.7 0.0073 15.1 2.7 1.1 1 0 0 1 1 1 1 Weak chloroplast movement under blue light Mod_r PF07200.13 OQR95853.1 - 0.015 15.4 2.8 0.037 14.1 2.8 1.6 1 0 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein FAA_hydro_N_2 PF18288.1 OQR95853.1 - 0.039 14.4 0.2 0.11 13.0 0.2 1.7 1 0 0 1 1 1 0 Fumarylacetoacetase N-terminal domain 2 DUF2316 PF10078.9 OQR95853.1 - 0.18 12.0 2.5 18 5.7 0.3 2.7 2 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2316) TPR_MLP1_2 PF07926.12 OQR95854.1 - 0.0021 18.1 16.3 0.0045 17.0 16.3 1.5 1 0 0 1 1 1 1 TPR/MLP1/MLP2-like protein UPF0242 PF06785.11 OQR95854.1 - 0.083 13.0 9.8 0.14 12.2 9.8 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF3979 PF13141.6 OQR95854.1 - 0.31 11.3 1.7 0.91 9.8 1.6 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3979) ETS_PEA3_N PF04621.13 OQR95854.1 - 0.41 10.5 8.0 0.82 9.5 8.0 1.7 1 1 0 1 1 1 0 PEA3 subfamily ETS-domain transcription factor N terminal domain CC2-LZ PF16516.5 OQR95854.1 - 1.6 9.1 14.6 6.7 7.1 2.5 2.6 1 1 1 2 2 2 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator ADIP PF11559.8 OQR95854.1 - 1.8 8.6 21.5 0.52 10.4 16.2 2.2 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding Tubulin_3 PF14881.6 OQR95856.1 - 2.9e-13 49.9 0.0 4.4e-13 49.3 0.0 1.2 1 0 0 1 1 1 1 Tubulin domain Tubulin PF00091.25 OQR95856.1 - 0.013 15.7 0.0 0.021 15.0 0.0 1.3 1 0 0 1 1 1 0 Tubulin/FtsZ family, GTPase domain Pkinase PF00069.25 OQR95857.1 - 1.6e-40 139.1 0.0 9.6e-30 103.8 0.0 2.1 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OQR95857.1 - 1.3e-38 132.8 0.0 1.3e-27 96.8 0.0 2.1 1 1 1 2 2 2 2 Protein tyrosine kinase Ank_2 PF12796.7 OQR95858.1 - 1.5e-151 493.4 16.7 5.7e-18 65.3 0.0 12.1 1 1 9 11 11 11 11 Ankyrin repeats (3 copies) Ank PF00023.30 OQR95858.1 - 2.8e-128 413.3 43.2 3.2e-07 30.5 0.0 24.0 22 2 2 24 24 24 23 Ankyrin repeat Ank_4 PF13637.6 OQR95858.1 - 7e-113 367.7 0.7 2.6e-09 37.4 0.0 15.6 8 6 6 15 15 15 15 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQR95858.1 - 4.7e-102 321.5 15.0 0.00029 21.0 0.0 24.0 23 1 1 24 24 24 22 Ankyrin repeat Ank_5 PF13857.6 OQR95858.1 - 2.9e-67 221.9 25.9 1.9e-08 34.4 0.2 16.6 7 5 13 20 20 20 18 Ankyrin repeats (many copies) Imm_superinfect PF14373.6 OQR95858.1 - 9e-07 28.7 6.7 1.2e+02 2.7 0.0 11.8 15 0 0 15 15 15 0 Superinfection immunity protein Nipped-B_C PF12830.7 OQR95858.1 - 0.00077 19.5 1.6 1.6 8.6 0.0 4.9 5 1 0 6 6 6 1 Sister chromatid cohesion C-terminus RNase_PH_C PF03725.15 OQR95858.1 - 0.0018 18.3 4.5 84 3.3 0.0 8.6 6 4 4 10 10 10 0 3' exoribonuclease family, domain 2 T6SS-SciN PF12790.7 OQR95858.1 - 0.012 15.4 11.0 36 4.1 0.0 8.9 12 0 0 12 12 12 0 Type VI secretion lipoprotein, VasD, EvfM, TssJ, VC_A0113 Arg_repressor PF01316.21 OQR95858.1 - 0.017 14.8 2.9 1.4e+02 2.3 0.1 6.6 7 0 0 7 7 7 0 Arginine repressor, DNA binding domain Q_salvage PF10343.9 OQR95859.1 - 1.4e-32 113.4 0.0 4.7e-32 111.7 0.0 1.8 1 1 0 1 1 1 1 Potential Queuosine, Q, salvage protein family AA_kinase PF00696.28 OQR95860.1 - 8.7e-29 100.8 0.3 1e-28 100.6 0.3 1.1 1 0 0 1 1 1 1 Amino acid kinase family ABC2_membrane_3 PF12698.7 OQR95862.1 - 2.2e-33 115.8 45.9 2.4e-17 63.1 6.5 3.8 4 1 1 5 5 5 3 ABC-2 family transporter protein ABC_tran PF00005.27 OQR95862.1 - 6.6e-30 104.4 0.0 1.7e-29 103.1 0.0 1.8 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 OQR95862.1 - 8.8e-09 35.6 0.0 1.2e-05 25.2 0.0 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system ABC2_membrane_2 PF12679.7 OQR95862.1 - 4.6e-06 26.1 2.0 0.00093 18.6 3.7 3.9 4 0 0 4 4 4 2 ABC-2 family transporter protein AAA_23 PF13476.6 OQR95862.1 - 0.02 15.4 0.4 0.032 14.7 0.4 1.3 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 OQR95862.1 - 0.045 13.5 0.4 0.1 12.3 0.4 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain SMC_N PF02463.19 OQR95862.1 - 0.08 12.4 0.2 5.6 6.3 0.0 2.2 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain YwiC PF14256.6 OQR95862.1 - 8.9 6.6 14.4 12 6.2 3.1 3.7 3 0 0 3 3 3 0 YwiC-like protein Nrap_D3 PF17404.2 OQR95863.1 - 5.9e-39 133.7 0.1 1.9e-38 132.0 0.0 1.9 2 0 0 2 2 2 1 Nrap protein domain 3 Nrap PF03813.14 OQR95863.1 - 3e-34 118.3 0.5 5.5e-34 117.4 0.5 1.5 1 0 0 1 1 1 1 Nrap protein domain 1 Nrap_D4 PF17405.2 OQR95863.1 - 2.3e-31 108.8 0.0 5.5e-31 107.6 0.0 1.6 1 0 0 1 1 1 1 Nrap protein nucleotidyltransferase domain 4 Nrap_D5 PF17406.2 OQR95863.1 - 4.8e-29 101.2 7.1 1.6e-27 96.2 0.9 2.5 2 0 0 2 2 2 2 Nrap protein PAP/OAS1-like domain 5 Nrap_D2 PF17403.2 OQR95863.1 - 2.1e-23 82.8 6.2 4.9e-23 81.6 3.9 2.3 2 0 0 2 2 2 1 Nrap protein PAP/OAS-like domain Nrap_D6 PF17407.2 OQR95863.1 - 3.6e-19 69.3 0.0 7.9e-19 68.2 0.0 1.6 1 0 0 1 1 1 1 Nrap protein domain 6 ABC2_membrane_3 PF12698.7 OQR95864.1 - 6.6e-16 58.3 16.7 6.6e-16 58.3 16.7 2.3 1 1 2 3 3 3 2 ABC-2 family transporter protein ABC2_membrane_2 PF12679.7 OQR95864.1 - 0.0011 18.3 11.6 0.0011 18.3 11.6 2.4 2 1 1 3 3 3 1 ABC-2 family transporter protein DUF4736 PF15883.5 OQR95864.1 - 7.1 6.3 8.9 1.1 9.0 1.7 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4736) PKD_channel PF08016.12 OQR95866.1 - 4.5e-33 114.6 39.1 1.1e-14 54.0 12.0 5.8 4 2 2 6 6 6 5 Polycystin cation channel Ion_trans PF00520.31 OQR95866.1 - 6.3e-10 38.7 38.6 5.9e-08 32.2 16.4 3.2 2 1 0 2 2 2 2 Ion transport protein DUF2682 PF10909.8 OQR95866.1 - 0.0016 18.9 0.1 5 7.7 0.0 3.0 2 0 0 2 2 2 2 Protein of unknown function (DUF2682) DUF3278 PF11683.8 OQR95866.1 - 0.43 10.7 6.2 1.5 9.0 0.1 3.5 3 1 0 3 3 3 0 Protein of unknown function (DUF3278) Kazal_2 PF07648.15 OQR95867.1 - 1.5e-11 44.3 19.5 2.5e-08 33.9 0.5 3.5 2 1 1 3 3 3 3 Kazal-type serine protease inhibitor domain Kazal_1 PF00050.21 OQR95867.1 - 5e-06 26.4 2.4 5e-06 26.4 2.4 3.4 1 1 2 3 3 3 2 Kazal-type serine protease inhibitor domain TRIC PF05197.13 OQR95868.1 - 0.033 13.8 0.3 0.052 13.1 0.3 1.2 1 0 0 1 1 1 0 TRIC channel Birna_RdRp PF04197.12 OQR95868.1 - 0.039 12.3 0.0 0.05 11.9 0.0 1.1 1 0 0 1 1 1 0 Birnavirus RNA dependent RNA polymerase (VP1) GMP_synt_C PF00958.22 OQR95870.1 - 7.3e-44 147.8 0.0 1.3e-43 146.9 0.0 1.5 1 0 0 1 1 1 1 GMP synthase C terminal domain GATase PF00117.28 OQR95870.1 - 3.4e-35 121.6 0.0 5.1e-35 121.0 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 OQR95870.1 - 4.7e-10 39.6 0.0 1.4e-09 38.1 0.0 1.8 1 1 0 1 1 1 1 Peptidase C26 NAD_synthase PF02540.17 OQR95870.1 - 2.1e-08 33.6 0.0 1.9e-06 27.2 0.0 2.2 2 0 0 2 2 2 1 NAD synthase tRNA_Me_trans PF03054.16 OQR95870.1 - 0.0001 21.3 0.0 0.00023 20.1 0.0 1.6 2 0 0 2 2 2 1 tRNA methyl transferase ThiI PF02568.14 OQR95870.1 - 0.00072 19.2 0.0 0.0026 17.3 0.0 1.8 2 0 0 2 2 2 1 Thiamine biosynthesis protein (ThiI) PAPS_reduct PF01507.19 OQR95870.1 - 0.0027 17.8 0.0 0.0088 16.1 0.0 1.8 2 0 0 2 2 2 1 Phosphoadenosine phosphosulfate reductase family QueC PF06508.13 OQR95870.1 - 0.03 13.8 0.0 0.38 10.2 0.0 2.2 2 0 0 2 2 2 0 Queuosine biosynthesis protein QueC ATP_bind_3 PF01171.20 OQR95870.1 - 0.12 12.1 0.0 0.2 11.4 0.0 1.4 1 0 0 1 1 1 0 PP-loop family Asn_synthase PF00733.21 OQR95870.1 - 0.14 11.8 0.0 0.23 11.1 0.0 1.2 1 0 0 1 1 1 0 Asparagine synthase ABC_membrane PF00664.23 OQR95871.1 - 1.3e-60 205.4 31.5 7.5e-32 111.1 10.7 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 OQR95871.1 - 9.1e-50 168.7 0.0 3.2e-30 105.4 0.0 2.4 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 OQR95871.1 - 2.7e-09 36.8 6.3 0.0086 15.5 0.0 4.2 2 2 1 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 OQR95871.1 - 4.1e-06 26.5 0.4 0.026 14.3 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 OQR95871.1 - 5.5e-06 26.4 0.2 0.051 13.7 0.1 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_16 PF13191.6 OQR95871.1 - 0.00067 20.1 0.0 0.51 10.7 0.0 2.8 2 0 0 2 2 2 1 AAA ATPase domain RsgA_GTPase PF03193.16 OQR95871.1 - 0.00086 19.2 2.4 0.95 9.4 0.2 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_22 PF13401.6 OQR95871.1 - 0.00092 19.5 0.1 0.53 10.5 0.0 2.8 3 0 0 3 3 2 1 AAA domain Dynamin_N PF00350.23 OQR95871.1 - 0.0011 19.1 3.6 0.37 10.8 0.2 2.5 2 0 0 2 2 2 2 Dynamin family AAA_21 PF13304.6 OQR95871.1 - 0.0025 17.7 0.7 0.68 9.7 0.0 2.6 3 0 0 3 3 2 1 AAA domain, putative AbiEii toxin, Type IV TA system DUF815 PF05673.13 OQR95871.1 - 0.0053 15.9 0.9 0.2 10.8 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF815) NB-ARC PF00931.22 OQR95871.1 - 0.0082 15.4 1.0 0.16 11.1 0.1 2.8 3 0 0 3 3 3 1 NB-ARC domain 60KD_IMP PF02096.20 OQR95871.1 - 0.009 15.9 0.4 0.009 15.9 0.4 2.2 2 0 0 2 2 2 1 60Kd inner membrane protein DUF87 PF01935.17 OQR95871.1 - 0.01 15.9 3.4 0.089 12.9 0.1 2.3 2 0 0 2 2 2 0 Helicase HerA, central domain AAA_23 PF13476.6 OQR95871.1 - 0.013 16.0 0.3 2.2 8.7 0.1 2.3 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 OQR95871.1 - 0.018 14.8 0.5 1.1 8.9 0.0 2.6 2 1 0 2 2 2 0 AAA domain NACHT PF05729.12 OQR95871.1 - 0.04 13.8 0.2 1.3 8.9 0.0 2.7 2 0 0 2 2 2 0 NACHT domain Cytidylate_kin PF02224.18 OQR95871.1 - 0.044 13.5 0.3 0.12 12.1 0.0 1.9 2 0 0 2 2 2 0 Cytidylate kinase AAA_33 PF13671.6 OQR95871.1 - 0.054 13.6 0.5 0.79 9.9 0.1 2.4 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 OQR95871.1 - 0.079 13.5 0.2 20 5.8 0.0 2.5 2 0 0 2 2 2 0 AAA domain T2SSE PF00437.20 OQR95871.1 - 0.086 11.9 0.7 2.4 7.1 0.0 2.5 3 0 0 3 3 3 0 Type II/IV secretion system protein Viral_helicase1 PF01443.18 OQR95871.1 - 0.088 12.5 0.3 4.8 6.9 0.0 2.9 3 0 0 3 3 3 0 Viral (Superfamily 1) RNA helicase cobW PF02492.19 OQR95871.1 - 0.099 12.2 3.0 1.9 8.0 0.3 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain FtsK_SpoIIIE PF01580.18 OQR95871.1 - 0.17 11.2 2.6 5.7 6.2 0.5 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family Roc PF08477.13 OQR95871.1 - 0.27 11.5 0.9 12 6.2 0.1 3.0 3 0 0 3 3 2 0 Ras of Complex, Roc, domain of DAPkinase WD40 PF00400.32 OQR95872.1 - 3.2e-08 34.1 8.5 0.032 15.1 0.0 5.2 5 1 0 5 5 5 4 WD domain, G-beta repeat Nucleoporin_N PF08801.11 OQR95872.1 - 0.0017 17.2 0.0 0.017 13.9 0.0 2.3 2 1 1 3 3 3 1 Nup133 N terminal like Tfb4 PF03850.14 OQR95872.1 - 0.12 11.9 0.0 0.21 11.0 0.0 1.4 1 0 0 1 1 1 0 Transcription factor Tfb4 TF_Zn_Ribbon PF08271.12 OQR95873.1 - 2.1e-06 27.1 6.8 2e-05 24.0 0.8 3.7 3 1 0 3 3 3 1 TFIIB zinc-binding zf-C2HE PF16278.5 OQR95873.1 - 0.00036 20.9 3.5 9.6 6.7 0.0 4.6 4 0 0 4 4 4 2 C2HE / C2H2 / C2HC zinc-binding finger zinc_ribbon_12 PF11331.8 OQR95873.1 - 0.03 14.1 2.2 0.3 10.9 0.1 3.0 3 0 0 3 3 3 0 Probable zinc-ribbon domain zinc_ribbon_5 PF13719.6 OQR95873.1 - 0.038 13.7 1.1 9.1 6.1 0.1 2.6 2 0 0 2 2 2 0 zinc-ribbon domain zf-C2H2 PF00096.26 OQR95873.1 - 0.046 14.2 1.4 0.046 14.2 1.4 4.1 4 0 0 4 4 4 0 Zinc finger, C2H2 type Nudix_N_2 PF14803.6 OQR95873.1 - 0.046 13.7 5.3 9.7 6.2 0.1 4.2 4 0 0 4 4 4 0 Nudix N-terminal zf-C2H2_4 PF13894.6 OQR95873.1 - 0.049 14.5 15.9 0.35 11.8 0.6 4.4 4 0 0 4 4 4 0 C2H2-type zinc finger zinc_ribbon_4 PF13717.6 OQR95873.1 - 0.072 13.0 3.9 2.8 8.0 0.1 2.9 3 0 0 3 3 3 0 zinc-ribbon domain IBR PF01485.21 OQR95873.1 - 0.093 13.0 0.9 17 5.7 0.1 2.8 2 0 0 2 2 2 0 IBR domain, a half RING-finger domain zf-Sec23_Sec24 PF04810.15 OQR95873.1 - 0.11 12.6 2.3 3.5 7.8 0.1 3.3 3 0 0 3 3 3 0 Sec23/Sec24 zinc finger CpXC PF14353.6 OQR95873.1 - 0.14 12.2 1.8 9.5 6.3 0.1 3.5 4 0 0 4 4 4 0 CpXC protein zf-C2H2_2 PF12756.7 OQR95873.1 - 0.35 11.2 10.8 0.22 11.9 0.4 3.6 4 0 0 4 4 3 0 C2H2 type zinc-finger (2 copies) FYDLN_acid PF09538.10 OQR95873.1 - 0.37 11.5 4.8 11 6.7 0.3 3.1 3 0 0 3 3 3 0 Protein of unknown function (FYDLN_acid) Zn-ribbon_8 PF09723.10 OQR95873.1 - 0.55 10.4 6.6 13 5.9 0.1 3.6 3 0 0 3 3 3 0 Zinc ribbon domain ADK_lid PF05191.14 OQR95873.1 - 1.5 8.9 6.2 5.4 7.1 0.1 3.3 3 0 0 3 3 3 0 Adenylate kinase, active site lid ATP_synt_H PF05493.13 OQR95874.1 - 0.0094 16.4 0.9 0.0094 16.4 0.9 2.1 1 1 1 2 2 2 2 ATP synthase subunit H zf-HC5HC2H PF13771.6 OQR95875.1 - 0.0061 16.8 1.0 0.0087 16.3 1.0 1.2 1 0 0 1 1 1 1 PHD-like zinc-binding domain SRC-1 PF08832.10 OQR95875.1 - 0.016 16.3 0.4 0.032 15.3 0.1 1.7 2 0 0 2 2 2 0 Steroid receptor coactivator Holin_BhlA PF10960.8 OQR95875.1 - 0.13 12.3 0.2 0.21 11.6 0.2 1.3 1 0 0 1 1 1 0 BhlA holin family zf-DNL PF05180.12 OQR95876.1 - 8e-29 99.4 0.1 1.1e-28 98.9 0.1 1.2 1 0 0 1 1 1 1 DNL zinc finger YABBY PF04690.13 OQR95876.1 - 0.041 14.5 0.0 0.047 14.2 0.0 1.1 1 0 0 1 1 1 0 YABBY protein RNHCP PF12647.7 OQR95876.1 - 0.082 12.9 0.6 1.1 9.3 0.0 2.2 1 1 1 2 2 2 0 RNHCP domain zf-TFIIB PF13453.6 OQR95876.1 - 0.47 9.8 2.7 0.43 9.9 0.9 1.9 2 0 0 2 2 2 0 Transcription factor zinc-finger zinc_ribbon_4 PF13717.6 OQR95876.1 - 0.9 9.5 3.4 7.5 6.6 3.5 2.3 1 1 0 1 1 1 0 zinc-ribbon domain CRAL_TRIO_2 PF13716.6 OQR95877.1 - 4.2e-28 98.2 0.1 9.2e-28 97.1 0.1 1.6 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain Macro PF01661.21 OQR95877.1 - 7e-27 93.8 1.6 8.8e-27 93.5 0.3 1.8 2 0 0 2 2 2 1 Macro domain CRAL_TRIO PF00650.20 OQR95877.1 - 2.9e-07 30.4 0.3 1.5e-06 28.0 0.0 2.3 2 1 0 2 2 2 1 CRAL/TRIO domain Ion_trans PF00520.31 OQR95878.1 - 3.6e-83 278.6 109.8 4.6e-30 104.6 21.0 4.3 4 0 0 4 4 4 4 Ion transport protein TIP120 PF08623.10 OQR95878.1 - 8.2e-41 139.6 10.5 3.2e-40 137.7 0.2 5.2 5 1 0 5 5 5 1 TATA-binding protein interacting (TIP20) HEAT_2 PF13646.6 OQR95878.1 - 9.7e-18 64.4 1.2 0.14 12.5 0.0 7.9 5 1 2 7 7 7 4 HEAT repeats HEAT PF02985.22 OQR95878.1 - 4.6e-17 60.7 14.6 0.11 12.9 0.0 10.3 9 1 0 9 9 9 5 HEAT repeat IBR PF01485.21 OQR95878.1 - 1.3e-11 44.6 22.9 7.8e-08 32.4 6.9 3.9 4 0 0 4 4 3 2 IBR domain, a half RING-finger domain RWD PF05773.22 OQR95878.1 - 2.3e-11 44.0 0.1 6.7e-11 42.5 0.1 1.9 1 0 0 1 1 1 1 RWD domain EF-hand_7 PF13499.6 OQR95878.1 - 2e-10 41.0 1.4 0.00019 21.8 0.1 3.4 3 0 0 3 3 3 2 EF-hand domain pair HEAT_EZ PF13513.6 OQR95878.1 - 4.2e-10 39.9 12.3 3.6 8.2 0.1 10.6 10 0 0 10 10 10 1 HEAT-like repeat EF-hand_6 PF13405.6 OQR95878.1 - 1.1e-06 28.1 1.2 0.053 13.5 0.2 3.4 3 0 0 3 3 2 2 EF-hand domain EF-hand_1 PF00036.32 OQR95878.1 - 1.5e-06 27.3 1.3 0.059 13.0 0.2 3.0 2 0 0 2 2 2 2 EF hand RTP1_C1 PF10363.9 OQR95878.1 - 0.00047 20.3 7.9 0.23 11.7 0.1 6.8 7 0 0 7 7 7 1 Required for nuclear transport of RNA pol II C-terminus 1 Cnd1 PF12717.7 OQR95878.1 - 0.0015 18.6 20.3 4.9 7.2 0.6 8.7 8 1 2 10 10 10 1 non-SMC mitotic condensation complex subunit 1 EF-hand_8 PF13833.6 OQR95878.1 - 0.0022 17.8 7.5 0.017 14.9 0.2 3.4 4 0 0 4 4 4 1 EF-hand domain pair DFRP_C PF16543.5 OQR95878.1 - 0.021 15.3 0.2 0.021 15.3 0.2 2.0 2 0 0 2 2 1 0 DRG Family Regulatory Proteins, Tma46 EF-hand_5 PF13202.6 OQR95878.1 - 0.025 14.1 0.6 4 7.1 0.0 2.8 2 0 0 2 2 2 0 EF hand UME PF08064.13 OQR95878.1 - 0.043 13.7 6.1 14 5.7 0.0 5.2 5 0 0 5 5 3 0 UME (NUC010) domain HEAT_UF PF18817.1 OQR95878.1 - 0.068 13.4 3.6 0.1 12.8 0.1 3.0 3 0 0 3 3 2 0 Repeat of uncharacterized protein PH0542 SPARC_Ca_bdg PF10591.9 OQR95878.1 - 0.36 11.2 6.3 2.1 8.7 0.1 3.7 3 1 0 3 3 3 0 Secreted protein acidic and rich in cysteine Ca binding region HEAT_PBS PF03130.16 OQR95878.1 - 2.7 8.9 5.8 51 5.0 0.0 5.0 5 0 0 5 5 3 0 PBS lyase HEAT-like repeat Peptidase_M3 PF01432.20 OQR95881.1 - 6.5e-125 418.0 0.0 7.8e-125 417.7 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M3 Peptidase_M50B PF13398.6 OQR95881.1 - 0.036 13.7 0.2 0.092 12.4 0.2 1.6 1 0 0 1 1 1 0 Peptidase M50B-like E2F_TDP PF02319.20 OQR95882.1 - 6.3e-23 80.6 0.9 2.9e-12 46.4 0.1 2.6 2 0 0 2 2 2 2 E2F/DP family winged-helix DNA-binding domain B-block_TFIIIC PF04182.12 OQR95882.1 - 0.0006 19.9 0.4 1.6 9.0 0.1 2.4 2 0 0 2 2 2 2 B-block binding subunit of TFIIIC CLZ PF16526.5 OQR95882.1 - 0.016 15.6 1.4 0.85 10.0 0.4 2.5 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DivIC PF04977.15 OQR95882.1 - 0.33 10.7 2.2 0.83 9.5 2.2 1.6 1 0 0 1 1 1 0 Septum formation initiator Snapin_Pallidin PF14712.6 OQR95882.1 - 0.73 10.3 6.0 3.1 8.3 0.2 3.0 3 0 0 3 3 3 0 Snapin/Pallidin CENP-F_leu_zip PF10473.9 OQR95882.1 - 8.1 6.5 6.7 0.38 10.8 0.4 2.0 3 0 0 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 PIP5K PF01504.18 OQR95883.1 - 5.2e-70 235.8 0.0 1.3e-68 231.2 0.0 2.1 1 1 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase Frizzled PF01534.17 OQR95883.1 - 1.6e-05 24.1 14.9 0.00017 20.7 14.9 2.1 1 1 0 1 1 1 1 Frizzled/Smoothened family membrane region 7tm_2 PF00002.24 OQR95883.1 - 0.00085 18.7 11.5 0.00085 18.7 11.5 2.3 1 1 1 2 2 2 1 7 transmembrane receptor (Secretin family) 7TM_GPCR_Srsx PF10320.9 OQR95883.1 - 0.018 14.4 7.6 0.028 13.8 7.6 1.2 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srsx INTS5_C PF14838.6 OQR95884.1 - 1.8e-15 56.6 4.9 1.5e-13 50.3 1.2 2.5 2 0 0 2 2 2 2 Integrator complex subunit 5 C-terminus CAP_GLY PF01302.25 OQR95885.1 - 8.3e-21 73.8 0.1 1.4e-20 73.0 0.1 1.4 1 0 0 1 1 1 1 CAP-Gly domain DnaJ PF00226.31 OQR95885.1 - 6e-17 61.5 0.4 1.1e-16 60.7 0.4 1.4 1 0 0 1 1 1 1 DnaJ domain RPT PF13446.6 OQR95885.1 - 0.062 13.2 0.9 2 8.4 0.0 2.6 2 1 0 2 2 2 0 A repeated domain in UCH-protein Pkinase PF00069.25 OQR95886.1 - 3.2e-52 177.5 0.0 8.9e-52 176.1 0.0 1.8 1 0 0 1 1 1 1 Protein kinase domain DUF4201 PF13870.6 OQR95886.1 - 9.5e-42 142.7 36.6 9.5e-42 142.7 36.6 3.9 3 1 0 4 4 4 1 Domain of unknown function (DUF4201) Pkinase_Tyr PF07714.17 OQR95886.1 - 1.1e-25 90.4 0.0 2.7e-25 89.1 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase FGGY_C PF02782.16 OQR95886.1 - 3.9e-18 65.9 0.1 8e-18 64.9 0.1 1.6 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.21 OQR95886.1 - 1.4e-09 37.9 0.0 8.3e-06 25.5 0.0 2.7 2 0 0 2 2 2 2 FGGY family of carbohydrate kinases, N-terminal domain APH PF01636.23 OQR95886.1 - 0.00027 21.0 3.1 0.047 13.6 0.0 4.0 3 1 1 4 4 4 1 Phosphotransferase enzyme family RIO1 PF01163.22 OQR95886.1 - 0.02 14.5 0.4 0.02 14.5 0.4 2.9 2 0 0 2 2 2 0 RIO1 family HSP70 PF00012.20 OQR95887.1 - 1.5e-228 759.9 8.5 1.5e-228 759.9 8.5 1.3 2 0 0 2 2 2 1 Hsp70 protein MreB_Mbl PF06723.13 OQR95887.1 - 1.3e-13 50.5 0.6 2.1e-12 46.5 0.1 2.2 2 0 0 2 2 2 1 MreB/Mbl protein TPR_2 PF07719.17 OQR95887.1 - 1.3e-07 31.1 16.1 0.03 14.4 0.2 4.8 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.6 OQR95887.1 - 1.7e-07 30.9 5.4 0.018 15.2 0.2 4.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 OQR95887.1 - 9.1e-06 25.3 16.4 0.00014 21.5 0.3 4.5 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.6 OQR95887.1 - 0.00093 18.8 9.3 0.0069 16.0 1.6 3.1 2 1 1 3 3 3 2 TPR repeat TPR_17 PF13431.6 OQR95887.1 - 0.006 16.9 8.4 0.84 10.2 0.8 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_20 PF14561.6 OQR95887.1 - 0.02 15.2 0.0 0.02 15.2 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat Hydantoinase_A PF01968.18 OQR95887.1 - 0.035 13.4 0.2 4.6 6.4 0.1 2.8 2 0 0 2 2 2 0 Hydantoinase/oxoprolinase DDE_Tnp_IS1 PF03400.13 OQR95887.1 - 0.11 12.9 0.1 0.32 11.3 0.0 1.8 2 0 0 2 2 2 0 IS1 transposase FtsA PF14450.6 OQR95887.1 - 0.11 12.9 6.3 14 6.2 0.2 3.9 3 2 0 3 3 3 0 Cell division protein FtsA TPR_19 PF14559.6 OQR95887.1 - 8.7 6.9 12.9 7 7.3 0.3 3.7 3 1 0 3 3 3 0 Tetratricopeptide repeat W2 PF02020.18 OQR95888.1 - 1.5e-10 41.1 0.7 1.5e-10 41.1 0.7 1.9 2 1 0 2 2 2 1 eIF4-gamma/eIF5/eIF2-epsilon RR_TM4-6 PF06459.12 OQR95888.1 - 0.3 10.9 8.7 0.64 9.8 8.7 1.5 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 POPLD PF08170.12 OQR95888.1 - 0.97 9.8 4.2 33 4.9 3.1 2.5 2 0 0 2 2 2 0 POPLD (NUC188) domain RNA_pol_Rpc4 PF05132.14 OQR95888.1 - 9.8 6.6 8.0 21 5.5 8.0 1.5 1 0 0 1 1 1 0 RNA polymerase III RPC4 EF-hand_1 PF00036.32 OQR95889.1 - 2.8e-24 82.8 9.4 1.8e-06 27.1 0.0 5.7 5 0 0 5 5 5 5 EF hand EF-hand_7 PF13499.6 OQR95889.1 - 7.8e-23 80.7 11.2 1.4e-08 35.0 0.2 4.1 4 0 0 4 4 4 3 EF-hand domain pair EF-hand_6 PF13405.6 OQR95889.1 - 2.6e-19 67.4 10.5 4.6e-05 23.0 0.2 6.0 5 0 0 5 5 5 5 EF-hand domain EF-hand_5 PF13202.6 OQR95889.1 - 2.1e-14 52.2 5.5 0.0013 18.2 0.2 5.4 5 0 0 5 5 5 3 EF hand EF-hand_8 PF13833.6 OQR95889.1 - 2.6e-14 52.8 10.2 0.00077 19.3 0.1 5.7 5 0 0 5 5 5 5 EF-hand domain pair WD40 PF00400.32 OQR95889.1 - 1.8e-10 41.2 8.9 3.5 8.7 0.1 8.0 8 0 0 8 8 8 4 WD domain, G-beta repeat EF-hand_9 PF14658.6 OQR95889.1 - 3.3e-05 24.1 0.3 0.041 14.2 0.1 3.1 3 0 0 3 3 3 2 EF-hand domain EF-hand_4 PF12763.7 OQR95889.1 - 0.012 15.5 1.3 17 5.4 0.5 3.6 2 1 1 3 3 3 0 Cytoskeletal-regulatory complex EF hand MutS_III PF05192.18 OQR95891.1 - 7.8e-21 75.2 0.1 1.3e-20 74.4 0.1 1.3 1 0 0 1 1 1 1 MutS domain III MutS_IV PF05190.18 OQR95891.1 - 0.00094 19.5 0.0 0.0042 17.4 0.0 2.1 1 0 0 1 1 1 1 MutS family domain IV GSP_synth PF03738.14 OQR95893.1 - 5.9e-64 216.6 0.0 9.3e-64 215.9 0.0 1.2 1 0 0 1 1 1 1 Glutathionylspermidine synthase preATP-grasp CHAP PF05257.16 OQR95893.1 - 6e-08 33.1 0.1 1.4e-07 32.0 0.1 1.7 1 0 0 1 1 1 1 CHAP domain DUF739 PF05339.11 OQR95893.1 - 0.058 13.6 0.0 0.17 12.0 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF739) Mpv17_PMP22 PF04117.12 OQR95894.1 - 1.1e-09 38.3 5.1 2.3e-05 24.5 0.5 2.5 2 0 0 2 2 2 2 Mpv17 / PMP22 family nos_propeller_2 PF18793.1 OQR95894.1 - 0.059 13.7 0.0 7.1 7.0 0.0 3.6 2 2 2 4 4 4 0 Nitrous oxide reductase propeller repeat 2 Mito_carr PF00153.27 OQR95896.1 - 6.4e-108 353.0 10.8 1.4e-21 76.2 0.0 6.1 6 0 0 6 6 6 6 Mitochondrial carrier protein V4R PF02830.18 OQR95896.1 - 0.0038 17.2 0.1 1.7 8.7 0.0 2.7 2 0 0 2 2 2 2 V4R domain VPS13 PF16908.5 OQR95897.1 - 2.3e-50 171.6 6.5 1.2e-47 162.7 1.9 3.8 3 0 0 3 3 3 2 Vacuolar sorting-associated protein 13, N-terminal Chorein_N PF12624.7 OQR95897.1 - 9.1e-27 93.5 0.1 2.5e-25 88.8 0.1 2.9 2 0 0 2 2 2 1 N-terminal region of Chorein or VPS13 SHR-BD PF06650.12 OQR95897.1 - 1.4e-20 73.8 0.0 2e-19 70.1 0.0 2.6 2 0 0 2 2 2 1 SHR-binding domain of vacuolar-sorting associated protein 13 VPS13_mid_rpt PF16910.5 OQR95897.1 - 2.1e-17 63.3 7.6 1.8e-08 34.1 0.1 5.4 3 2 0 3 3 3 2 Repeating coiled region of VPS13 VPS13_C PF16909.5 OQR95897.1 - 8.1e-09 35.5 0.0 2e-08 34.2 0.0 1.7 1 0 0 1 1 1 1 Vacuolar-sorting-associated 13 protein C-terminal PDZ_6 PF17820.1 OQR95897.1 - 4e-06 26.6 0.0 9.5e-06 25.4 0.0 1.6 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 OQR95897.1 - 0.00046 20.5 0.0 0.0012 19.2 0.0 1.6 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 OQR95897.1 - 0.0022 18.3 0.0 0.034 14.5 0.0 2.7 2 0 0 2 2 2 1 PDZ domain Tricorn_PDZ PF14685.6 OQR95897.1 - 0.01 15.8 0.0 0.032 14.2 0.0 1.8 1 0 0 1 1 1 0 Tricorn protease PDZ domain Apt1 PF10351.9 OQR95897.1 - 0.024 13.5 0.0 0.085 11.7 0.0 1.9 1 0 0 1 1 1 0 Golgi-body localisation protein domain TMEM234 PF10639.9 OQR95897.1 - 0.098 12.7 0.1 0.62 10.1 0.1 2.3 2 0 0 2 2 2 0 Putative transmembrane family 234 Trypsin_2 PF13365.6 OQR95898.1 - 2.9e-31 109.4 0.6 4.5e-31 108.8 0.6 1.3 1 0 0 1 1 1 1 Trypsin-like peptidase domain Trypsin PF00089.26 OQR95898.1 - 1.1e-14 54.8 0.1 2e-14 53.9 0.1 1.4 1 0 0 1 1 1 1 Trypsin PDZ_6 PF17820.1 OQR95898.1 - 1.5e-11 43.9 0.0 4e-11 42.6 0.0 1.8 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 OQR95898.1 - 1.9e-09 37.7 0.0 4.8e-09 36.4 0.0 1.7 1 0 0 1 1 1 1 PDZ domain Peptidase_S46 PF10459.9 OQR95898.1 - 1.3e-05 24.1 0.6 0.022 13.4 0.3 2.1 2 0 0 2 2 2 2 Peptidase S46 PDZ PF00595.24 OQR95898.1 - 1.6e-05 25.2 0.0 3.9e-05 23.9 0.0 1.7 1 0 0 1 1 1 1 PDZ domain Peptidase_S29 PF02907.15 OQR95898.1 - 0.071 12.8 0.0 0.19 11.5 0.0 1.7 1 1 0 1 1 1 0 Hepatitis C virus NS3 protease Peptidase_S7 PF00949.21 OQR95898.1 - 0.084 12.7 0.3 0.21 11.4 0.3 1.7 1 0 0 1 1 1 0 Peptidase S7, Flavivirus NS3 serine protease Speriolin_N PF15058.6 OQR95898.1 - 0.095 12.8 0.2 0.17 12.0 0.2 1.3 1 0 0 1 1 1 0 Speriolin N terminus RPA_C PF08784.11 OQR95899.1 - 1.6e-11 44.8 0.9 3.7e-11 43.6 0.1 1.9 2 0 0 2 2 2 1 Replication protein A C terminal tRNA_anti-codon PF01336.25 OQR95899.1 - 2.4e-05 24.3 0.0 3.9e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA_anti_2 PF13742.6 OQR95899.1 - 0.014 15.6 0.2 0.13 12.5 0.1 2.1 2 0 0 2 2 2 0 OB-fold nucleic acid binding domain RMI2 PF16100.5 OQR95899.1 - 0.079 12.8 0.0 0.12 12.2 0.0 1.2 1 0 0 1 1 1 0 RecQ-mediated genome instability protein 2 Qn_am_d_aII PF14930.6 OQR95899.1 - 0.095 13.0 0.1 0.39 11.1 0.0 2.0 2 0 0 2 2 2 0 Quinohemoprotein amine dehydrogenase, alpha subunit domain II SecA_SW PF07516.13 OQR95899.1 - 0.16 12.0 0.0 0.21 11.6 0.0 1.2 1 0 0 1 1 1 0 SecA Wing and Scaffold domain Ank_4 PF13637.6 OQR95900.1 - 7.7e-44 147.5 2.4 1.7e-13 50.8 0.0 5.9 2 2 4 6 6 6 6 Ankyrin repeats (many copies) Ank_2 PF12796.7 OQR95900.1 - 4.9e-39 132.8 0.0 6.8e-21 74.7 0.0 3.0 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.30 OQR95900.1 - 7.2e-37 124.2 0.2 4.1e-08 33.3 0.0 6.2 6 0 0 6 6 6 6 Ankyrin repeat Ank_5 PF13857.6 OQR95900.1 - 1e-29 102.2 0.9 1.4e-07 31.6 0.0 5.4 2 2 4 6 6 6 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQR95900.1 - 1.9e-27 92.3 0.2 2.5e-06 27.4 0.0 6.0 6 0 0 6 6 6 4 Ankyrin repeat EF-hand_6 PF13405.6 OQR95902.1 - 3.3e-05 23.5 0.1 0.0025 17.6 0.0 2.6 3 0 0 3 3 3 1 EF-hand domain EF-hand_1 PF00036.32 OQR95902.1 - 0.00015 21.0 0.3 0.014 14.9 0.0 2.6 3 0 0 3 3 3 2 EF hand EF-hand_7 PF13499.6 OQR95902.1 - 0.00082 19.8 0.1 0.0017 18.8 0.1 1.5 1 0 0 1 1 1 1 EF-hand domain pair CC2D2AN-C2 PF15625.6 OQR95903.1 - 3e-19 69.4 0.1 7.7e-19 68.1 0.1 1.6 1 0 0 1 1 1 1 CC2D2A N-terminal C2 domain C2 PF00168.30 OQR95903.1 - 0.00093 19.5 0.3 1.2 9.5 0.0 2.6 2 0 0 2 2 2 2 C2 domain DUF5327 PF17261.2 OQR95903.1 - 0.22 12.3 3.1 1.6 9.6 0.0 3.0 3 0 0 3 3 3 0 Family of unknown function (DUF5327) Ago_PAZ PF18309.1 OQR95904.1 - 0.018 15.7 1.0 6.9 7.4 0.0 2.3 2 0 0 2 2 2 0 Argonaute PAZ domain WRC PF08879.10 OQR95904.1 - 0.029 14.1 4.1 2.1 8.1 0.7 2.7 2 0 0 2 2 2 0 WRC Spem1 PF15670.5 OQR95904.1 - 1.8 8.1 7.4 1.5 8.3 4.7 1.8 1 1 1 2 2 2 0 Spermatid maturation protein 1 RabGAP-TBC PF00566.18 OQR95905.1 - 7.3e-39 133.7 7.1 2.9e-37 128.4 7.1 2.2 1 1 0 1 1 1 1 Rab-GTPase-TBC domain Ank_2 PF12796.7 OQR95906.1 - 3.2e-09 37.3 0.1 1.4e-08 35.2 0.0 2.2 2 2 1 3 3 3 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OQR95906.1 - 1.5e-07 31.1 0.1 0.015 15.8 0.0 3.4 2 1 1 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 OQR95906.1 - 6.8e-07 29.4 0.4 0.048 14.0 0.2 3.4 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 OQR95906.1 - 1.1e-06 28.8 0.1 0.038 14.4 0.1 3.1 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.6 OQR95906.1 - 4.3e-05 24.0 0.1 0.28 11.8 0.0 3.2 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Mesd PF10185.9 OQR95908.1 - 1.1e-18 67.7 12.3 4.9e-11 42.8 1.7 2.2 2 0 0 2 2 2 2 Chaperone for wingless signalling and trafficking of LDL receptor DNA_pol_E_B PF04042.16 OQR95909.1 - 1.5e-37 129.0 0.3 2.2e-37 128.4 0.3 1.3 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B DNA_pol_D_N PF18018.1 OQR95909.1 - 6.4e-31 107.1 0.0 1.1e-30 106.4 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase delta subunit OB-fold domain COG6 PF06419.11 OQR95910.1 - 1.8e-85 287.4 0.1 2.5e-85 287.0 0.1 1.1 1 0 0 1 1 1 1 Conserved oligomeric complex COG6 F_actin_bind PF08919.10 OQR95910.1 - 0.063 13.4 5.1 0.36 11.0 0.1 3.2 2 1 0 3 3 3 0 F-actin binding TPR_MalT PF17874.1 OQR95911.1 - 0.0005 19.5 0.7 0.00078 18.9 0.7 1.2 1 0 0 1 1 1 1 MalT-like TPR region TPR_12 PF13424.6 OQR95911.1 - 0.085 13.2 0.7 14 6.0 0.1 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat UbiA PF01040.18 OQR95912.1 - 3.3e-54 183.8 12.7 4.1e-54 183.5 12.7 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family Lipase_GDSL_2 PF13472.6 OQR95913.1 - 1.4e-52 178.7 0.1 1.2e-27 97.4 0.0 2.1 2 0 0 2 2 2 2 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 OQR95913.1 - 5.8e-34 117.8 0.0 1.7e-19 70.6 0.0 2.4 2 0 0 2 2 2 2 GDSL-like Lipase/Acylhydrolase Bcl-2_3 PF15286.6 OQR95913.1 - 0.07 13.8 0.0 10 6.8 0.0 2.6 2 1 0 2 2 2 0 Apoptosis regulator M11, B cell 2 leukaemia/lymphoma like SNURF PF07192.11 OQR95913.1 - 0.091 12.6 0.0 23 4.9 0.0 3.5 4 0 0 4 4 4 0 SNURF/RPN4 protein GSCFA PF08885.11 OQR95913.1 - 0.17 11.5 0.0 0.71 9.5 0.0 1.9 2 0 0 2 2 2 0 GSCFA family GCM PF03615.15 OQR95913.1 - 0.18 11.7 0.0 1.5 8.7 0.0 2.3 2 0 0 2 2 2 0 GCM motif protein Iso_dh PF00180.20 OQR95917.1 - 8.7e-71 238.9 0.0 1.2e-70 238.4 0.0 1.2 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase CBFD_NFYB_HMF PF00808.23 OQR95917.1 - 9e-10 38.7 0.1 3e-09 37.0 0.1 2.0 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Phe_ZIP PF08916.11 OQR95917.1 - 0.2 12.4 0.2 0.2 12.4 0.2 2.4 3 0 0 3 3 3 0 Phenylalanine zipper CENP-T_N PF16171.5 OQR95917.1 - 0.32 9.9 3.1 0.53 9.1 3.1 1.3 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T N-terminus RNase_P_p30 PF01876.16 OQR95918.1 - 2.1e-50 171.2 0.1 3e-50 170.7 0.1 1.2 1 0 0 1 1 1 1 RNase P subunit p30 LRR_9 PF14580.6 OQR95919.1 - 1.8e-56 190.4 41.1 2.3e-14 53.3 1.8 7.5 3 1 4 7 7 7 7 Leucine-rich repeat LRR_4 PF12799.7 OQR95919.1 - 1.5e-52 174.6 106.9 1.9e-07 31.3 4.7 16.3 13 5 4 18 18 18 14 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 OQR95919.1 - 2.2e-45 152.2 90.2 1.2e-07 31.4 3.5 11.3 8 2 1 10 10 10 10 Leucine rich repeat HTH_3 PF01381.22 OQR95919.1 - 0.017 15.2 0.3 3.5 7.7 0.0 3.1 3 0 0 3 3 3 0 Helix-turn-helix LRR_6 PF13516.6 OQR95919.1 - 0.045 13.8 67.7 0.6 10.3 0.2 16.3 18 0 0 18 18 18 0 Leucine Rich repeat LRR_2 PF07723.13 OQR95919.1 - 7 7.5 16.6 2.1e+02 2.8 0.1 8.9 10 0 0 10 10 10 0 Leucine Rich Repeat Popeye PF04831.13 OQR95920.1 - 7.9 6.6 7.6 5.5 7.1 1.4 2.7 2 1 0 2 2 2 0 Popeye protein conserved region Ank_2 PF12796.7 OQR95922.1 - 1.2e-56 189.3 8.6 1.3e-17 64.2 0.2 6.4 2 1 3 6 6 6 5 Ankyrin repeats (3 copies) Ank PF00023.30 OQR95922.1 - 1e-52 174.3 17.2 4.6e-05 23.7 0.0 11.8 11 1 0 11 11 11 11 Ankyrin repeat Ank_4 PF13637.6 OQR95922.1 - 3.5e-43 145.4 3.8 9.3e-10 38.9 0.0 8.3 4 2 5 9 9 9 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQR95922.1 - 2.5e-38 125.7 6.7 0.0093 16.4 0.0 11.6 11 1 1 12 12 12 10 Ankyrin repeat Ank_5 PF13857.6 OQR95922.1 - 4.9e-34 116.0 14.6 4e-07 30.2 0.1 8.3 3 2 5 9 9 9 8 Ankyrin repeats (many copies) HP0268 PF18618.1 OQR95922.1 - 0.17 12.3 0.0 38 4.8 0.0 2.8 3 0 0 3 3 3 0 HP0268 Imm_superinfect PF14373.6 OQR95922.1 - 0.5 10.3 2.2 12 5.9 0.0 4.1 5 0 0 5 5 5 0 Superinfection immunity protein Ank_2 PF12796.7 OQR95923.1 - 2.4e-48 162.6 12.1 7.3e-13 48.9 2.4 5.8 2 2 3 5 5 5 5 Ankyrin repeats (3 copies) Ank PF00023.30 OQR95923.1 - 7.1e-38 127.4 16.3 0.00047 20.5 0.1 10.2 9 1 1 10 10 10 8 Ankyrin repeat Ank_4 PF13637.6 OQR95923.1 - 7.4e-37 125.3 9.1 1.1e-05 25.9 0.0 8.6 4 3 4 8 8 8 8 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQR95923.1 - 2.8e-28 94.8 5.0 0.0074 16.7 0.0 10.9 11 0 0 11 11 11 6 Ankyrin repeat Ank_5 PF13857.6 OQR95923.1 - 1.1e-26 92.6 12.1 3.5e-07 30.4 0.1 8.1 5 2 3 8 8 8 8 Ankyrin repeats (many copies) YfmQ PF10787.9 OQR95923.1 - 0.0033 17.2 0.1 1.3 8.8 0.0 3.1 3 0 0 3 3 3 2 Uncharacterised protein from bacillus cereus group Glyco_hydro_30C PF17189.4 OQR95923.1 - 2.5 8.4 6.1 25 5.2 1.1 3.0 3 0 0 3 3 3 0 Glycosyl hydrolase family 30 beta sandwich domain Ctr PF04145.15 OQR95925.1 - 3.5e-22 79.6 0.7 5.3e-22 79.0 0.7 1.3 1 0 0 1 1 1 1 Ctr copper transporter family Zn_Tnp_IS1595 PF12760.7 OQR95925.1 - 0.063 13.3 1.2 2.5 8.1 0.3 2.4 2 0 0 2 2 2 0 Transposase zinc-ribbon domain PhnA_Zn_Ribbon PF08274.12 OQR95925.1 - 0.46 10.5 2.8 11 6.1 0.1 2.9 3 0 0 3 3 3 0 PhnA Zinc-Ribbon Prok-RING_4 PF14447.6 OQR95925.1 - 0.7 9.8 5.9 1.2 9.1 0.2 3.0 3 0 0 3 3 3 0 Prokaryotic RING finger family 4 Tubulin PF00091.25 OQR95926.1 - 4.4e-43 147.8 0.1 2.3e-31 109.5 0.0 2.1 1 1 1 2 2 2 2 Tubulin/FtsZ family, GTPase domain Xpo1 PF08389.12 OQR95927.1 - 2e-22 79.9 7.5 1.5e-21 77.0 1.2 3.6 3 0 0 3 3 3 1 Exportin 1-like protein IBN_N PF03810.19 OQR95927.1 - 3.7e-08 33.2 0.6 2.7e-07 30.4 0.2 2.6 2 1 0 2 2 2 1 Importin-beta N-terminal domain Hormone_1 PF00103.20 OQR95927.1 - 0.025 14.3 0.0 0.083 12.6 0.0 1.9 1 0 0 1 1 1 0 Somatotropin hormone family Thiolase_N PF00108.23 OQR95928.1 - 3.3e-75 252.8 6.5 5.1e-75 252.2 6.5 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 OQR95928.1 - 6.3e-50 167.9 0.1 1.2e-49 167.1 0.1 1.4 1 0 0 1 1 1 1 Thiolase, C-terminal domain DnaJ PF00226.31 OQR95928.1 - 9.4e-20 70.5 0.1 1.8e-19 69.6 0.1 1.5 1 0 0 1 1 1 1 DnaJ domain Ctr PF04145.15 OQR95928.1 - 1.3e-14 55.0 11.5 2.6e-12 47.6 11.5 2.5 1 1 0 1 1 1 1 Ctr copper transporter family HMA PF00403.26 OQR95928.1 - 3.9e-06 27.2 0.1 1.1e-05 25.8 0.0 1.9 2 0 0 2 2 2 1 Heavy-metal-associated domain ACP_syn_III_C PF08541.10 OQR95928.1 - 0.0051 17.0 0.1 0.038 14.2 0.0 2.7 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal Tubulin_C PF03953.17 OQR95929.1 - 3.3e-41 140.4 0.0 3.7e-41 140.2 0.0 1.0 1 0 0 1 1 1 1 Tubulin C-terminal domain Ank_2 PF12796.7 OQR95931.1 - 2.2e-17 63.4 4.6 0.00065 20.2 0.1 4.8 3 2 1 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQR95931.1 - 1.1e-14 54.6 10.0 0.022 15.4 0.0 7.7 7 1 1 8 8 8 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 OQR95931.1 - 2.2e-10 40.6 14.3 3.9 7.9 0.0 10.0 5 4 7 12 12 12 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQR95931.1 - 1.6e-06 28.0 9.0 27 5.8 0.0 9.3 8 1 1 9 9 9 1 Ankyrin repeat DUF5049 PF16468.5 OQR95931.1 - 0.0013 18.5 0.5 17 5.4 0.0 5.1 5 1 1 6 6 6 2 Domain of unknown function (DUF5049) TPR_12 PF13424.6 OQR95932.1 - 2.3e-06 27.8 1.6 7.7e-05 22.9 0.0 2.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 OQR95932.1 - 0.042 14.1 0.1 5.2 7.5 0.0 3.4 3 1 0 3 3 3 0 Tetratricopeptide repeat C2 PF00168.30 OQR95933.1 - 9.2e-09 35.5 0.0 1.3e-08 35.0 0.0 1.2 1 0 0 1 1 1 1 C2 domain Ank_5 PF13857.6 OQR95933.1 - 0.046 14.1 0.0 0.099 13.0 0.0 1.5 1 0 0 1 1 1 0 Ankyrin repeats (many copies) Abhydrolase_1 PF00561.20 OQR95934.1 - 2.6e-13 50.2 0.0 7.7e-13 48.7 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 OQR95934.1 - 4.8e-09 35.8 0.0 1.4e-08 34.4 0.0 1.7 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 OQR95934.1 - 9.8e-07 29.6 0.0 1.5e-06 29.0 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Palm_thioest PF02089.15 OQR95934.1 - 0.049 13.5 0.0 0.079 12.8 0.0 1.3 1 1 0 1 1 1 0 Palmitoyl protein thioesterase Peptidase_S15 PF02129.18 OQR95934.1 - 0.065 12.8 0.0 0.13 11.8 0.0 1.5 1 1 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) Rad60-SLD_2 PF13881.6 OQR95936.1 - 1.8e-11 44.1 0.0 2.1e-11 43.9 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like FoP_duplication PF13865.6 OQR95937.1 - 2.1e-16 60.2 17.5 3.4e-16 59.5 17.5 1.3 1 0 0 1 1 1 1 C-terminal duplication domain of Friend of PRMT1 DBINO PF13892.6 OQR95937.1 - 0.94 9.8 6.0 0.1 12.9 1.8 1.6 2 0 0 2 2 2 0 DNA-binding domain Pec_lyase_N PF04431.13 OQR95937.1 - 2.5 8.4 8.4 8.1 6.8 0.3 2.9 3 0 0 3 3 3 0 Pectate lyase, N terminus DUF2967 PF11179.8 OQR95937.1 - 3.1 5.8 6.3 3.2 5.7 6.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2967) DUF1282 PF06930.12 OQR95938.1 - 0.0094 15.7 2.6 0.02 14.7 2.6 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1282) DUF1673 PF07895.11 OQR95938.1 - 0.076 12.7 5.7 0.13 12.0 5.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1673) Caudo_TAP PF02413.17 OQR95938.1 - 0.29 11.3 2.7 0.43 10.7 2.7 1.2 1 0 0 1 1 1 0 Caudovirales tail fibre assembly protein, lambda gpK Disintegrin PF00200.23 OQR95940.1 - 2.4e-61 204.5 237.6 8.4e-06 26.5 10.5 17.5 13 8 0 13 13 13 13 Disintegrin NDUFV3 PF15880.5 OQR95941.1 - 0.066 13.2 0.0 0.12 12.5 0.0 1.4 1 0 0 1 1 1 0 NADH dehydrogenase [ubiquinone] flavoprotein 3, mitochondrial PIP5K PF01504.18 OQR95942.1 - 2.3e-71 240.2 0.0 4.1e-71 239.4 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase 7TM_GPCR_Srsx PF10320.9 OQR95942.1 - 7.1e-06 25.6 9.2 1.5e-05 24.6 9.2 1.4 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx Mito_carr PF00153.27 OQR95944.1 - 2.6e-75 248.4 1.3 9.1e-24 83.2 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Ephrin_rec_like PF07699.13 OQR95945.1 - 0.00041 20.1 4.8 0.00041 20.1 4.8 18.3 12 9 6 19 19 19 2 Putative ephrin-receptor like Frataxin_Cyay PF01491.16 OQR95946.1 - 0.0012 18.8 0.0 0.0017 18.4 0.0 1.1 1 0 0 1 1 1 1 Frataxin-like domain Ion_trans PF00520.31 OQR95948.1 - 2e-23 82.9 16.6 3.1e-23 82.3 16.6 1.3 1 0 0 1 1 1 1 Ion transport protein cNMP_binding PF00027.29 OQR95948.1 - 1e-09 38.3 0.0 1.9e-09 37.5 0.0 1.4 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Ion_trans_2 PF07885.16 OQR95948.1 - 7.7e-08 32.2 6.8 7.7e-08 32.2 6.8 2.5 2 0 0 2 2 2 1 Ion channel MeaB PF03308.16 OQR95949.1 - 6.4e-93 310.6 0.3 8.4e-93 310.2 0.3 1.1 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB cobW PF02492.19 OQR95949.1 - 6.3e-08 32.4 1.0 3.1e-07 30.1 1.0 2.0 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain ATP_bind_1 PF03029.17 OQR95949.1 - 3.9e-06 26.8 1.3 0.00047 20.0 0.1 2.8 2 1 1 3 3 3 1 Conserved hypothetical ATP binding protein AAA_30 PF13604.6 OQR95949.1 - 0.00037 20.3 0.2 0.0014 18.4 0.1 1.9 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 OQR95949.1 - 0.00053 20.3 0.5 0.047 13.9 0.0 2.6 3 0 0 3 3 2 1 AAA domain AAA_24 PF13479.6 OQR95949.1 - 0.001 18.8 1.0 0.0065 16.2 0.0 2.5 1 1 1 3 3 3 1 AAA domain FtsK_SpoIIIE PF01580.18 OQR95949.1 - 0.0014 18.0 0.0 0.0023 17.3 0.0 1.3 1 0 0 1 1 1 1 FtsK/SpoIIIE family CbiA PF01656.23 OQR95949.1 - 0.0026 17.8 0.0 0.0064 16.5 0.0 1.6 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ABC_tran PF00005.27 OQR95949.1 - 0.011 16.3 0.2 0.03 14.8 0.2 1.8 1 0 0 1 1 1 0 ABC transporter MMR_HSR1 PF01926.23 OQR95949.1 - 0.012 15.7 0.2 0.026 14.6 0.2 1.9 1 1 0 1 1 1 0 50S ribosome-binding GTPase GTP_EFTU PF00009.27 OQR95949.1 - 0.015 14.9 0.1 4.8 6.7 0.0 2.4 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain IstB_IS21 PF01695.17 OQR95949.1 - 0.021 14.6 0.0 0.046 13.5 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein NTPase_1 PF03266.15 OQR95949.1 - 0.026 14.4 0.2 0.045 13.7 0.2 1.3 1 0 0 1 1 1 0 NTPase CLP1_P PF16575.5 OQR95949.1 - 0.032 14.0 0.0 0.097 12.5 0.0 1.8 2 0 0 2 2 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop Thymidylate_kin PF02223.17 OQR95949.1 - 0.033 13.9 0.0 0.07 12.8 0.0 1.5 1 0 0 1 1 1 0 Thymidylate kinase MobB PF03205.14 OQR95949.1 - 0.036 14.0 0.3 0.17 11.8 0.0 2.2 3 0 0 3 3 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_31 PF13614.6 OQR95949.1 - 0.037 14.0 0.0 0.088 12.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 OQR95949.1 - 0.038 14.5 0.5 0.1 13.1 0.5 1.8 1 0 0 1 1 1 0 AAA domain SRP54 PF00448.22 OQR95949.1 - 0.046 13.4 0.0 0.11 12.1 0.0 1.6 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain ParA PF10609.9 OQR95949.1 - 0.069 12.6 0.4 0.069 12.6 0.4 1.9 2 0 0 2 2 2 0 NUBPL iron-transfer P-loop NTPase AAA_33 PF13671.6 OQR95949.1 - 0.072 13.2 0.0 0.19 11.9 0.0 1.8 1 0 0 1 1 1 0 AAA domain Fer4_NifH PF00142.18 OQR95949.1 - 0.093 12.2 0.1 0.15 11.5 0.1 1.3 1 0 0 1 1 1 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family ArsA_ATPase PF02374.15 OQR95949.1 - 0.096 11.9 2.7 0.089 12.0 1.1 1.6 2 0 0 2 2 2 0 Anion-transporting ATPase AAA_10 PF12846.7 OQR95949.1 - 0.1 11.5 0.0 0.18 10.7 0.0 1.5 1 0 0 1 1 1 0 AAA-like domain AAA_23 PF13476.6 OQR95949.1 - 0.1 13.1 0.1 0.25 11.8 0.1 1.6 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 OQR95949.1 - 0.12 12.2 0.2 0.3 10.8 0.2 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain SAPIS-gp6 PF16722.5 OQR95949.1 - 0.13 12.7 0.1 0.3 11.5 0.1 1.6 1 0 0 1 1 1 0 Pathogenicity island protein gp6 in Staphylococcus Zeta_toxin PF06414.12 OQR95949.1 - 0.14 11.4 0.1 0.25 10.6 0.1 1.5 1 0 0 1 1 1 0 Zeta toxin RNA_helicase PF00910.22 OQR95949.1 - 0.18 12.2 0.0 0.38 11.2 0.0 1.6 1 0 0 1 1 1 0 RNA helicase IstB_IS21 PF01695.17 OQR95950.1 - 0.015 15.0 0.0 0.038 13.7 0.0 1.6 2 0 0 2 2 2 0 IstB-like ATP binding protein DUF87 PF01935.17 OQR95950.1 - 0.14 12.2 0.1 0.36 10.9 0.1 1.6 1 0 0 1 1 1 0 Helicase HerA, central domain SET PF00856.28 OQR95951.1 - 1.4e-12 48.4 0.0 1.9e-11 44.6 0.0 2.2 2 0 0 2 2 2 1 SET domain PMI_typeI PF01238.21 OQR95951.1 - 0.0027 17.0 0.1 0.02 14.1 0.1 2.1 2 0 0 2 2 2 1 Phosphomannose isomerase type I TPR_12 PF13424.6 OQR95951.1 - 0.12 12.7 0.0 2.3 8.6 0.0 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat EzrA PF06160.12 OQR95951.1 - 0.16 10.2 0.3 0.28 9.3 0.3 1.3 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA Herpes_UL31 PF02718.14 OQR95951.1 - 2.4 7.0 8.0 12 4.7 8.0 2.2 1 1 0 1 1 1 0 Herpesvirus UL31-like protein Nuc_sug_transp PF04142.15 OQR95952.1 - 2.1e-06 27.1 12.6 7.7e-06 25.3 12.6 1.9 1 1 0 1 1 1 1 Nucleotide-sugar transporter CRT-like PF08627.10 OQR95952.1 - 0.002 17.2 9.2 0.002 17.2 9.2 2.5 2 1 1 3 3 3 2 CRT-like, chloroquine-resistance transporter-like Synaptobrevin PF00957.21 OQR95953.1 - 5.5e-41 138.3 17.4 4.2e-22 77.7 5.3 3.3 3 0 0 3 3 3 2 Synaptobrevin Longin PF13774.6 OQR95953.1 - 9.4e-12 44.8 0.1 2.9e-06 27.2 0.0 2.8 2 0 0 2 2 2 2 Regulated-SNARE-like domain SHNi-TPR PF10516.9 OQR95953.1 - 1.2e-08 34.3 0.0 2.4e-08 33.3 0.0 1.6 1 0 0 1 1 1 1 SHNi-TPR TPR_2 PF07719.17 OQR95953.1 - 5e-05 23.1 2.7 0.11 12.7 0.0 4.0 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 OQR95953.1 - 5.7e-05 22.8 0.1 0.16 11.9 0.0 3.1 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 OQR95953.1 - 0.00059 19.8 1.7 0.15 12.3 0.1 3.8 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 OQR95953.1 - 0.0018 18.5 0.7 3.3 8.1 0.0 3.2 2 0 0 2 2 2 2 Tetratricopeptide repeat SoDot-IcmSS PF16848.5 OQR95953.1 - 0.0029 17.6 10.7 0.0071 16.3 0.7 3.5 4 0 0 4 4 3 1 Substrate of the Dot/Icm secretion system, putative Sarcoglycan_2 PF05510.13 OQR95953.1 - 0.0045 15.8 0.9 0.019 13.8 0.1 2.0 2 0 0 2 2 2 1 Sarcoglycan alpha/epsilon Fzo_mitofusin PF04799.13 OQR95953.1 - 0.017 14.7 12.5 0.037 13.6 1.6 3.0 3 0 0 3 3 3 0 fzo-like conserved region TMEM223 PF14640.6 OQR95953.1 - 0.021 15.0 0.9 0.14 12.3 0.1 2.5 2 0 0 2 2 2 0 Transmembrane protein 223 ODV-E18 PF10717.9 OQR95953.1 - 0.022 14.6 0.4 0.022 14.6 0.4 2.1 2 0 0 2 2 2 0 Occlusion-derived virus envelope protein ODV-E18 Baculo_VP91_N PF08475.10 OQR95953.1 - 0.026 14.2 0.3 0.25 11.0 0.0 2.4 2 0 0 2 2 2 0 Viral capsid protein 91 N-terminal DUF4330 PF14221.6 OQR95953.1 - 0.06 13.6 2.0 3.7 7.7 0.1 3.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4330) Tweety PF04906.13 OQR95953.1 - 0.07 11.8 6.2 0.026 13.2 0.8 2.5 2 0 0 2 2 2 0 Tweety TPR_14 PF13428.6 OQR95953.1 - 0.076 13.9 0.8 31 5.7 0.1 3.3 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF3149 PF11346.8 OQR95953.1 - 0.081 12.6 3.5 0.2 11.3 3.5 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3149) TPR_10 PF13374.6 OQR95953.1 - 0.14 12.1 1.0 18 5.4 0.2 3.2 2 0 0 2 2 2 0 Tetratricopeptide repeat POTRA_TamA_1 PF17243.2 OQR95953.1 - 0.16 12.1 2.8 7.9 6.7 0.1 3.3 3 0 0 3 3 3 0 POTRA domain TamA domain 1 LPD22 PF18834.1 OQR95953.1 - 0.39 11.0 4.7 0.25 11.6 1.5 2.4 2 0 0 2 2 2 0 Large polyvalent protein associated domain 22 TPR_16 PF13432.6 OQR95953.1 - 0.39 11.4 1.5 10 6.9 0.0 2.9 3 0 0 3 3 2 0 Tetratricopeptide repeat EphA2_TM PF14575.6 OQR95953.1 - 1.8 9.5 4.5 3.9 8.4 0.0 3.6 4 0 0 4 4 4 0 Ephrin type-A receptor 2 transmembrane domain Init_tRNA_PT PF04179.12 OQR95953.1 - 7.8 6.9 6.1 11 6.4 1.2 3.5 3 1 1 4 4 4 0 Rit1 DUSP-like domain Nuc_sug_transp PF04142.15 OQR95954.1 - 7.3e-09 35.2 1.0 1.4e-08 34.3 1.0 1.4 1 0 0 1 1 1 1 Nucleotide-sugar transporter PUNUT PF16913.5 OQR95954.1 - 0.0021 17.4 7.0 0.0021 17.4 7.0 2.3 2 1 0 2 2 2 1 Purine nucleobase transmembrane transport EamA PF00892.20 OQR95954.1 - 0.019 15.1 5.9 0.019 15.1 5.9 4.1 3 1 1 4 4 4 0 EamA-like transporter family CRT-like PF08627.10 OQR95954.1 - 3.8 6.3 20.4 0.29 10.0 9.6 3.2 3 1 0 3 3 3 0 CRT-like, chloroquine-resistance transporter-like SQAPI PF16845.5 OQR95955.1 - 0.078 13.3 0.1 0.24 11.7 0.1 1.9 1 1 0 1 1 1 0 Aspartic acid proteinase inhibitor Yae1_N PF09811.9 OQR95956.1 - 4.3e-13 48.7 3.0 6.4e-13 48.2 3.0 1.3 1 0 0 1 1 1 1 Essential protein Yae1, N terminal AAA_33 PF13671.6 OQR95957.1 - 8.1e-11 42.3 0.0 1.7e-10 41.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 OQR95957.1 - 5.3e-09 35.6 0.0 9.6e-09 34.8 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin KTI12 PF08433.10 OQR95957.1 - 6e-06 25.9 0.0 1e-05 25.2 0.0 1.3 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_18 PF13238.6 OQR95957.1 - 0.00028 21.4 0.0 0.0013 19.3 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 OQR95957.1 - 0.00062 20.2 0.0 0.0013 19.2 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain CPT PF07931.12 OQR95957.1 - 0.0018 18.1 0.4 0.019 14.8 0.4 2.2 1 1 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein AAA_30 PF13604.6 OQR95957.1 - 0.0026 17.5 0.0 0.0051 16.6 0.0 1.6 1 1 0 1 1 1 1 AAA domain SRP54 PF00448.22 OQR95957.1 - 0.0028 17.3 0.3 0.034 13.8 0.1 2.5 2 1 0 2 2 2 1 SRP54-type protein, GTPase domain AAA PF00004.29 OQR95957.1 - 0.0042 17.5 0.0 0.01 16.3 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 OQR95957.1 - 0.0061 16.6 0.0 0.012 15.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) APS_kinase PF01583.20 OQR95957.1 - 0.012 15.5 0.0 0.024 14.5 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_22 PF13401.6 OQR95957.1 - 0.017 15.4 0.0 0.055 13.7 0.0 1.8 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 OQR95957.1 - 0.038 14.5 0.0 0.087 13.3 0.0 1.6 1 0 0 1 1 1 0 ABC transporter AAA_17 PF13207.6 OQR95957.1 - 0.059 13.8 0.0 0.17 12.3 0.0 1.9 1 1 0 1 1 1 0 AAA domain PEPCK_ATP PF01293.20 OQR95957.1 - 0.11 11.2 0.0 0.16 10.6 0.0 1.2 1 0 0 1 1 1 0 Phosphoenolpyruvate carboxykinase PGM_PMM_II PF02879.16 OQR95957.1 - 0.16 12.6 0.0 1.9 9.1 0.0 2.3 2 0 0 2 2 2 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II RCC1 PF00415.18 OQR95960.1 - 4.7e-73 241.6 16.4 1.9e-15 57.2 0.0 8.2 7 1 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 OQR95960.1 - 5.9e-44 147.0 21.0 2e-09 37.0 0.0 7.5 7 0 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat SUKH-3 PF14433.6 OQR95960.1 - 0.0033 17.9 2.5 37 4.8 0.0 5.1 4 1 2 6 6 6 1 SUKH-3 immunity protein DUF2625 PF10946.8 OQR95960.1 - 0.11 11.5 0.0 0.21 10.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function DUF2625 Thioredoxin_8 PF13905.6 OQR95961.1 - 5.4e-29 100.4 0.0 9.6e-29 99.6 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin PF00085.20 OQR95961.1 - 4.2e-10 39.5 0.1 6e-07 29.4 0.1 2.4 1 1 1 2 2 2 2 Thioredoxin fn3 PF00041.21 OQR95961.1 - 1.8e-08 34.6 1.3 0.0013 19.0 0.0 2.8 3 0 0 3 3 3 2 Fibronectin type III domain Redoxin PF08534.10 OQR95961.1 - 4e-05 23.4 0.0 7.3e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 OQR95961.1 - 5e-05 23.2 0.0 9e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_2 PF13098.6 OQR95961.1 - 0.00093 19.6 0.0 0.0023 18.4 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_9 PF14595.6 OQR95961.1 - 0.0019 17.9 0.0 0.016 15.0 0.0 2.2 1 1 0 1 1 1 1 Thioredoxin SCO1-SenC PF02630.14 OQR95961.1 - 0.078 12.9 0.0 0.17 11.8 0.0 1.5 1 0 0 1 1 1 0 SCO1/SenC Thioredoxin_7 PF13899.6 OQR95961.1 - 0.13 12.5 0.1 0.36 11.1 0.1 1.8 1 1 0 1 1 1 0 Thioredoxin-like Auts2 PF15336.6 OQR95962.1 - 0.75 9.9 7.5 3.4 7.7 4.6 2.2 1 1 1 2 2 2 0 Autism susceptibility gene 2 protein Kinesin PF00225.23 OQR95964.1 - 1.7e-79 267.2 5.7 1.7e-79 267.2 5.7 3.2 2 2 2 4 4 4 1 Kinesin motor domain Microtub_bd PF16796.5 OQR95964.1 - 1.7e-30 105.9 0.3 1.7e-30 105.9 0.3 4.0 2 2 2 4 4 4 1 Microtubule binding WW PF00397.26 OQR95964.1 - 2.8e-10 40.1 3.9 5.1e-10 39.3 3.9 1.4 1 0 0 1 1 1 1 WW domain Filament PF00038.21 OQR95964.1 - 2.8e-05 23.9 39.1 2.8e-05 23.9 39.1 2.3 1 1 1 2 2 2 1 Intermediate filament protein DUF2247 PF10004.9 OQR95964.1 - 3.5 7.4 11.9 0.052 13.3 2.1 2.8 2 1 1 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2247) HMMR_N PF15905.5 OQR95964.1 - 6.8 6.1 64.2 0.38 10.2 33.4 3.3 1 1 2 3 3 3 0 Hyaluronan mediated motility receptor N-terminal FAM184 PF15665.5 OQR95964.1 - 7.3 6.3 59.5 0.053 13.3 24.4 3.3 1 1 1 2 2 2 0 Family with sequence similarity 184, A and B RRM_2 PF04059.12 OQR95965.1 - 4.3e-45 151.9 0.5 7.9e-45 151.0 0.5 1.5 1 0 0 1 1 1 1 RNA recognition motif 2 zf-B_box PF00643.24 OQR95965.1 - 8.6e-06 25.8 27.1 0.0022 18.1 5.1 2.5 1 1 1 2 2 2 2 B-box zinc finger RRM_1 PF00076.22 OQR95965.1 - 0.0055 16.5 0.0 0.03 14.1 0.0 2.2 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-C2H2_jaz PF12171.8 OQR95965.1 - 0.05 13.9 3.6 1.3 9.4 0.0 3.8 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding Pkinase PF00069.25 OQR95966.1 - 9e-59 199.0 0.0 1.3e-58 198.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQR95966.1 - 6.7e-29 100.9 0.0 1e-28 100.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OQR95966.1 - 5.6e-05 22.6 0.0 9.3e-05 21.9 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 OQR95966.1 - 0.082 11.8 0.0 0.14 11.0 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain FYVE_2 PF02318.16 OQR95966.1 - 0.12 12.5 10.4 0.34 11.1 10.4 1.7 1 0 0 1 1 1 0 FYVE-type zinc finger IQ PF00612.27 OQR95968.1 - 0.00012 21.6 17.1 0.0027 17.4 1.0 3.9 3 0 0 3 3 3 2 IQ calmodulin-binding motif BORCS8 PF10167.9 OQR95968.1 - 0.21 11.5 1.6 9.8 6.2 0.1 2.7 2 0 0 2 2 2 0 BLOC-1-related complex sub-unit 8 VPS11_C PF12451.8 OQR95968.1 - 4.7 7.5 5.3 6.4 7.1 0.7 2.9 2 0 0 2 2 2 0 Vacuolar protein sorting protein 11 C terminal HA PF03457.14 OQR95969.1 - 3.6e-25 88.1 0.2 8.7e-11 42.0 0.0 3.1 3 0 0 3 3 3 3 Helicase associated domain Sod_Cu PF00080.20 OQR95970.1 - 1.2e-32 113.0 1.5 1.8e-32 112.4 1.5 1.2 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) Elicitin PF00964.17 OQR95970.1 - 4.8e-09 36.2 0.9 8.8e-09 35.3 0.9 1.5 1 0 0 1 1 1 1 Elicitin RNase_PH PF01138.21 OQR95973.1 - 1.4e-33 116.2 0.0 1.6e-18 67.5 0.0 2.6 2 0 0 2 2 2 2 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 OQR95973.1 - 4.8e-19 68.1 0.2 2.9e-12 46.4 0.0 3.0 3 0 0 3 3 3 2 3' exoribonuclease family, domain 2 KH_1 PF00013.29 OQR95973.1 - 2.6e-11 43.2 0.6 1.5e-10 40.7 0.6 2.2 2 0 0 2 2 2 1 KH domain KH_2 PF07650.17 OQR95973.1 - 0.00085 19.1 0.8 0.0057 16.5 0.1 2.4 1 1 1 2 2 2 1 KH domain S1 PF00575.23 OQR95973.1 - 0.025 14.9 0.4 0.42 11.0 0.4 2.4 1 1 0 1 1 1 0 S1 RNA binding domain MIT PF04212.18 OQR95974.1 - 0.12 12.5 1.1 13 6.0 0.0 2.6 3 0 0 3 3 3 0 MIT (microtubule interacting and transport) domain Aminotran_1_2 PF00155.21 OQR95975.1 - 1.5e-68 231.6 0.0 1.7e-68 231.4 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 OQR95975.1 - 5.9e-06 25.8 0.0 9e-06 25.2 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.19 OQR95975.1 - 4.8e-05 22.5 0.0 9.8e-05 21.5 0.0 1.5 2 0 0 2 2 2 1 Aminotransferase class-V SHMT PF00464.19 OQR95975.1 - 0.00051 18.8 0.0 0.017 13.7 0.0 2.6 1 1 0 1 1 1 1 Serine hydroxymethyltransferase Cys_Met_Meta_PP PF01053.20 OQR95975.1 - 0.0033 16.0 0.0 0.0048 15.5 0.0 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme HATPase_c_5 PF14501.6 OQR95975.1 - 0.019 14.9 0.0 0.037 13.9 0.0 1.5 1 0 0 1 1 1 0 GHKL domain Flg_hook PF02120.16 OQR95975.1 - 0.049 13.5 0.0 0.39 10.6 0.0 2.5 3 1 0 3 3 3 0 Flagellar hook-length control protein FliK DUF5633 PF18656.1 OQR95975.1 - 0.14 12.1 0.1 1.6 8.7 0.1 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5633) DegT_DnrJ_EryC1 PF01041.17 OQR95975.1 - 0.17 11.2 0.5 0.78 9.0 0.5 1.9 1 1 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Chitin_synth_1 PF01644.17 OQR95977.1 - 2.2e-48 164.3 0.0 3.2e-48 163.8 0.0 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_2 PF03142.15 OQR95977.1 - 3.9e-27 95.1 1.1 2.2e-22 79.4 0.1 3.1 3 1 0 3 3 3 2 Chitin synthase Glyco_trans_2_3 PF13632.6 OQR95977.1 - 4.7e-11 43.0 1.1 4.7e-11 43.0 1.1 1.8 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 OQR95977.1 - 2.5e-07 30.9 0.0 7.1e-07 29.3 0.0 1.8 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Chitin_synth_1N PF08407.11 OQR95977.1 - 0.0015 18.4 0.0 0.0073 16.2 0.0 2.1 2 0 0 2 2 2 1 Chitin synthase N-terminal MIT PF04212.18 OQR95977.1 - 0.051 13.7 0.0 0.051 13.7 0.0 2.0 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain ORC_WH_C PF18137.1 OQR95977.1 - 0.085 12.9 0.1 1.8 8.6 0.0 2.2 2 0 0 2 2 2 0 Origin recognition complex winged helix C-terminal HECT PF00632.25 OQR95979.1 - 2.3e-76 257.2 0.0 3.4e-76 256.7 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) PAP2 PF01569.21 OQR95979.1 - 2.5e-12 46.7 0.2 5.5e-12 45.6 0.2 1.5 1 0 0 1 1 1 1 PAP2 superfamily fn3 PF00041.21 OQR95979.1 - 4.4e-09 36.6 0.0 0.00054 20.3 0.0 2.6 2 0 0 2 2 2 2 Fibronectin type III domain WW PF00397.26 OQR95979.1 - 0.00015 21.8 2.2 0.0002 21.4 0.4 2.2 2 0 0 2 2 2 1 WW domain Gal_Lectin PF02140.18 OQR95980.1 - 1.2e-30 105.7 1.0 1e-14 54.7 0.0 2.3 2 0 0 2 2 2 2 Galactose binding lectin domain Mito_fiss_reg PF05308.11 OQR95980.1 - 6.6 6.7 5.7 9.8 6.2 5.7 1.2 1 0 0 1 1 1 0 Mitochondrial fission regulator PRIMA1 PF16101.5 OQR95980.1 - 7 6.7 11.0 16 5.6 11.0 1.5 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 Aldedh PF00171.22 OQR95982.1 - 3.3e-130 434.7 0.0 3.8e-130 434.5 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Ribosomal_L1 PF00687.21 OQR95983.1 - 1.3e-47 162.2 4.4 1.3e-47 162.2 4.4 3.1 2 1 0 2 2 2 1 Ribosomal protein L1p/L10e family DUF5593 PF18007.1 OQR95983.1 - 7.9 7.3 9.2 10 6.9 0.9 3.8 3 1 0 3 3 3 0 Domain of unknown function (DUF5593) AA_permease_2 PF13520.6 OQR95996.1 - 1.2e-39 136.4 41.7 1.4e-37 129.6 41.7 2.1 1 1 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 OQR95996.1 - 3.2e-31 108.4 27.4 3.2e-31 108.4 27.4 2.0 1 1 1 2 2 2 1 Amino acid permease AA_permease_C PF13906.6 OQR95996.1 - 4.8e-10 39.4 8.9 4.8e-10 39.4 8.9 3.8 4 0 0 4 4 4 1 C-terminus of AA_permease MscL PF01741.18 OQR95996.1 - 0.51 10.7 9.3 12 6.2 0.2 3.3 2 1 0 2 2 2 0 Large-conductance mechanosensitive channel, MscL AA_permease_2 PF13520.6 OQR95997.1 - 1e-42 146.4 21.8 1e-42 146.4 21.8 1.9 2 0 0 2 2 2 1 Amino acid permease AA_permease PF00324.21 OQR95997.1 - 2.9e-30 105.3 22.4 2.9e-30 105.3 22.4 2.3 3 0 0 3 3 3 1 Amino acid permease AA_permease_C PF13906.6 OQR95997.1 - 3.7e-07 30.1 7.3 3.7e-07 30.1 7.3 3.1 2 0 0 2 2 2 1 C-terminus of AA_permease Ion_trans PF00520.31 OQR95998.1 - 4.6e-12 45.7 8.2 1.3e-11 44.2 8.2 1.7 1 1 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 OQR95998.1 - 2.7e-08 33.7 6.7 6.9e-08 32.4 6.7 1.7 1 1 0 1 1 1 1 Ion channel cNMP_binding PF00027.29 OQR95998.1 - 8.4e-07 29.0 0.0 7.7e-06 25.9 0.0 2.3 2 0 0 2 2 2 1 Cyclic nucleotide-binding domain DUF1264 PF06884.11 OQR95998.1 - 0.025 14.2 0.0 0.04 13.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1264) DUF3585 PF12130.8 OQR96006.1 - 0.022 14.9 0.9 0.022 14.9 0.9 1.7 2 0 0 2 2 2 0 Bivalent Mical/EHBP Rab binding domain DUF1616 PF07760.11 OQR96006.1 - 0.039 13.3 0.3 0.06 12.7 0.2 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1616) Cupin_8 PF13621.6 OQR96007.1 - 6.4e-54 183.3 0.7 8.8e-54 182.9 0.7 1.2 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.12 OQR96007.1 - 0.024 14.1 0.2 0.23 10.9 0.0 2.2 2 0 0 2 2 2 0 Cupin superfamily protein GlcNAc PF11397.8 OQR96008.1 - 1e-55 189.7 1.4 7.7e-51 173.6 0.2 2.2 1 1 1 2 2 2 2 Glycosyltransferase (GlcNAc) Ank_2 PF12796.7 OQR96009.1 - 1.6e-12 47.8 0.0 2.2e-12 47.4 0.0 1.1 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 OQR96009.1 - 1.6e-11 44.1 0.0 1.5e-06 28.4 0.0 2.2 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.6 OQR96009.1 - 9.5e-11 41.7 0.0 5.5e-05 23.4 0.0 2.2 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQR96009.1 - 3.5e-09 36.2 0.0 6.8e-05 23.0 0.0 2.4 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.6 OQR96009.1 - 5.3e-09 36.4 0.0 1.3e-07 32.0 0.0 1.7 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ras PF00071.22 OQR96010.1 - 1e-65 220.2 0.9 1.4e-65 219.8 0.9 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OQR96010.1 - 3.7e-36 124.0 0.4 8.3e-36 122.8 0.1 1.7 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OQR96010.1 - 4.1e-17 62.2 0.1 5.9e-17 61.7 0.1 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family BRCT_2 PF16589.5 OQR96010.1 - 2.6e-07 31.0 0.0 4.9e-07 30.1 0.0 1.5 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 OQR96010.1 - 5.2e-06 26.8 0.0 1.3e-05 25.5 0.0 1.7 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 OQR96010.1 - 2.2e-05 24.3 0.1 4.5e-05 23.3 0.1 1.6 1 0 0 1 1 1 1 twin BRCT domain SRPRB PF09439.10 OQR96010.1 - 2.9e-05 23.6 0.1 4.7e-05 22.9 0.1 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 OQR96010.1 - 7.1e-05 22.9 0.0 0.00018 21.6 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 OQR96010.1 - 7.2e-05 22.2 0.0 0.00012 21.5 0.0 1.4 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region LIG3_BRCT PF16759.5 OQR96010.1 - 8.3e-05 22.8 0.0 0.00017 21.8 0.0 1.5 1 0 0 1 1 1 1 DNA ligase 3 BRCT domain RsgA_GTPase PF03193.16 OQR96010.1 - 8.4e-05 22.5 0.8 0.32 10.9 0.0 2.4 1 1 1 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 OQR96010.1 - 0.00058 19.5 0.3 0.001 18.6 0.2 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA PF00004.29 OQR96010.1 - 0.014 15.8 0.1 1.1 9.7 0.0 2.5 1 1 1 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 OQR96010.1 - 0.04 13.4 0.3 0.35 10.3 0.0 2.4 3 0 0 3 3 3 0 P-loop containing dynein motor region FeoB_N PF02421.18 OQR96010.1 - 0.06 12.9 0.1 0.39 10.2 0.1 2.1 1 1 0 1 1 1 0 Ferrous iron transport protein B RTT107_BRCT_5 PF16770.5 OQR96010.1 - 0.068 13.1 0.0 0.17 11.8 0.0 1.8 1 0 0 1 1 1 0 Regulator of Ty1 transposition protein 107 BRCT domain AAA_5 PF07728.14 OQR96010.1 - 0.091 12.8 0.0 0.25 11.3 0.0 1.8 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 OQR96010.1 - 0.094 13.1 0.0 0.15 12.4 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.6 OQR96010.1 - 0.1 12.4 0.3 0.31 10.8 0.0 1.9 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_22 PF13401.6 OQR96010.1 - 0.13 12.5 0.0 0.27 11.5 0.0 1.6 1 1 0 1 1 1 0 AAA domain PX PF00787.24 OQR96011.1 - 3.7e-11 43.0 0.0 6.6e-11 42.2 0.0 1.4 1 0 0 1 1 1 1 PX domain SQS_PSY PF00494.19 OQR96011.1 - 0.082 12.4 0.0 0.16 11.4 0.0 1.5 1 0 0 1 1 1 0 Squalene/phytoene synthase Mannosyl_trans3 PF11051.8 OQR96012.1 - 2.7e-08 33.5 0.1 2.7e-08 33.5 0.1 1.1 1 0 0 1 1 1 1 Mannosyltransferase putative Tubulin PF00091.25 OQR96013.1 - 7.3e-40 137.3 2.5 1.1e-39 136.7 2.5 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain FtsZ_C PF12327.8 OQR96013.1 - 6.8e-34 116.0 1.1 6.8e-34 116.0 1.1 2.2 2 0 0 2 2 2 1 FtsZ family, C-terminal domain Tubulin_2 PF13809.6 OQR96013.1 - 8.4 5.5 11.1 13 4.8 4.1 2.8 1 1 1 2 2 2 0 Tubulin like WD40 PF00400.32 OQR96014.1 - 1.6e-12 47.7 19.1 0.0014 19.4 1.0 6.0 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OQR96014.1 - 3.2e-07 30.5 1.2 0.11 12.8 0.1 3.7 2 2 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain AAA PF00004.29 OQR96015.1 - 7.5e-18 65.2 0.0 1.9e-17 64.0 0.0 1.7 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.6 OQR96015.1 - 5.3e-13 49.1 0.0 1.3e-10 41.3 0.0 2.3 1 1 0 1 1 1 1 DNA polymerase III, delta subunit Rep_fac_C PF08542.11 OQR96015.1 - 1.2e-11 44.9 0.1 4.1e-11 43.1 0.0 1.9 2 0 0 2 2 2 1 Replication factor C C-terminal domain Rad17 PF03215.15 OQR96015.1 - 3.1e-06 27.2 0.0 7.9e-06 25.9 0.0 1.7 1 1 0 1 1 1 1 Rad17 P-loop domain AAA_16 PF13191.6 OQR96015.1 - 3.2e-06 27.7 0.0 0.00037 20.9 0.0 2.5 1 1 1 2 2 2 1 AAA ATPase domain AAA_24 PF13479.6 OQR96015.1 - 6.3e-06 26.1 0.0 1.2e-05 25.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.12 OQR96015.1 - 6.6e-06 25.9 0.0 5e-05 23.1 0.0 2.2 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_assoc_2 PF16193.5 OQR96015.1 - 2.7e-05 24.4 0.0 6.9e-05 23.1 0.0 1.8 1 0 0 1 1 1 1 AAA C-terminal domain AAA_22 PF13401.6 OQR96015.1 - 0.00011 22.5 0.1 0.41 10.9 0.0 2.7 1 1 1 2 2 2 2 AAA domain DNA_pol3_delta PF06144.13 OQR96015.1 - 0.00024 20.9 0.0 0.00045 20.0 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA_11 PF13086.6 OQR96015.1 - 0.00037 20.4 0.0 0.00067 19.5 0.0 1.6 1 1 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 OQR96015.1 - 0.00039 19.8 0.0 0.037 13.4 0.0 2.2 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.26 OQR96015.1 - 0.00096 18.9 0.0 0.0025 17.6 0.0 1.6 1 1 0 1 1 1 1 Sigma-54 interaction domain ResIII PF04851.15 OQR96015.1 - 0.0041 17.1 0.0 0.014 15.4 0.0 1.7 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit AAA_5 PF07728.14 OQR96015.1 - 0.0053 16.7 0.0 0.03 14.3 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_14 PF13173.6 OQR96015.1 - 0.0057 16.7 0.0 0.011 15.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_3 PF07726.11 OQR96015.1 - 0.0071 16.2 0.0 0.012 15.4 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DEAD PF00270.29 OQR96015.1 - 0.015 15.1 0.1 0.097 12.4 0.0 2.1 1 1 1 2 2 2 0 DEAD/DEAH box helicase AAA_19 PF13245.6 OQR96015.1 - 0.016 15.5 0.1 0.15 12.4 0.0 2.1 1 1 1 2 2 2 0 AAA domain RNA_helicase PF00910.22 OQR96015.1 - 0.02 15.2 0.0 0.59 10.5 0.0 2.6 2 0 0 2 2 2 0 RNA helicase AAA_30 PF13604.6 OQR96015.1 - 0.027 14.2 0.0 0.088 12.5 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA_28 PF13521.6 OQR96015.1 - 0.061 13.6 0.0 0.098 12.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.13 OQR96015.1 - 0.063 12.4 0.0 0.099 11.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) TIP49 PF06068.13 OQR96015.1 - 0.065 12.4 0.0 0.19 10.9 0.0 1.7 2 0 0 2 2 2 0 TIP49 P-loop domain AAA_7 PF12775.7 OQR96015.1 - 0.066 12.7 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_18 PF13238.6 OQR96015.1 - 0.077 13.5 0.0 0.27 11.8 0.0 2.0 2 0 0 2 2 1 0 AAA domain DUF2075 PF09848.9 OQR96015.1 - 0.087 12.0 0.0 0.85 8.8 0.0 2.0 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) MCM PF00493.23 OQR96015.1 - 0.093 11.8 0.0 0.22 10.6 0.0 1.7 1 0 0 1 1 1 0 MCM P-loop domain PhoH PF02562.16 OQR96015.1 - 0.16 11.4 0.1 6.3 6.2 0.0 2.3 2 0 0 2 2 2 0 PhoH-like protein IQ PF00612.27 OQR96025.1 - 5.1e-39 128.4 62.4 4.8e-05 22.8 0.9 12.7 12 0 0 12 12 12 12 IQ calmodulin-binding motif TetR_C_24 PF17932.1 OQR96025.1 - 0.7 10.2 6.5 0.14 12.4 1.3 2.7 3 0 0 3 3 3 0 Tetracyclin repressor-like, C-terminal domain AA_permease_2 PF13520.6 OQR96026.1 - 9e-28 97.3 41.4 1e-27 97.0 40.3 1.6 1 1 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 OQR96026.1 - 2e-27 95.9 40.4 2.5e-27 95.6 40.4 1.0 1 0 0 1 1 1 1 Amino acid permease OMPdecase PF00215.24 OQR96027.1 - 5.6e-28 98.1 0.0 1.1e-27 97.1 0.0 1.5 1 0 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family Pribosyltran PF00156.27 OQR96027.1 - 2.8e-20 72.4 0.2 5.6e-20 71.5 0.2 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase domain Phage_Coat_Gp8 PF05371.12 OQR96027.1 - 0.09 12.6 2.7 0.37 10.6 2.7 2.0 1 0 0 1 1 1 0 Phage major coat protein, Gp8 PRTase_2 PF15609.6 OQR96027.1 - 0.13 11.8 0.4 0.26 10.8 0.4 1.4 1 0 0 1 1 1 0 Phosphoribosyl transferase AMP-binding PF00501.28 OQR96028.1 - 2e-62 211.2 0.0 2.9e-62 210.6 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme DAD PF02109.16 OQR96028.1 - 5.9e-43 145.6 2.0 1.1e-42 144.8 2.0 1.4 1 0 0 1 1 1 1 DAD family AMP-binding_C PF13193.6 OQR96028.1 - 2.7e-12 47.5 0.2 1.3e-11 45.2 0.1 2.2 3 0 0 3 3 3 1 AMP-binding enzyme C-terminal domain PAF-AH_p_II PF03403.13 OQR96029.1 - 1.3e-44 152.3 0.0 2.9e-44 151.1 0.0 1.5 1 1 0 1 1 1 1 Platelet-activating factor acetylhydrolase, isoform II Abhydrolase_1 PF00561.20 OQR96029.1 - 4.8e-09 36.2 0.1 7.4e-09 35.6 0.1 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Chlorophyllase2 PF12740.7 OQR96029.1 - 1.3e-07 30.8 0.4 6.8e-07 28.5 0.0 2.3 2 1 0 2 2 2 1 Chlorophyllase enzyme Hydrolase_4 PF12146.8 OQR96029.1 - 7.3e-07 28.7 0.3 1.6e-05 24.3 0.3 2.3 1 1 0 1 1 1 1 Serine aminopeptidase, S33 DLH PF01738.18 OQR96029.1 - 8.6e-05 22.2 0.0 0.00019 21.1 0.0 1.5 1 1 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_6 PF12697.7 OQR96029.1 - 0.00011 22.9 0.0 0.00017 22.3 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase PF07224.11 OQR96029.1 - 0.0022 17.1 0.0 0.19 10.7 0.0 2.3 2 0 0 2 2 2 1 Chlorophyllase Peptidase_S9 PF00326.21 OQR96029.1 - 0.013 15.0 0.0 0.048 13.1 0.0 1.9 2 0 0 2 2 2 0 Prolyl oligopeptidase family AXE1 PF05448.12 OQR96029.1 - 0.015 13.9 0.0 0.032 12.9 0.0 1.4 1 1 0 1 1 1 0 Acetyl xylan esterase (AXE1) Abhydrolase_5 PF12695.7 OQR96029.1 - 0.089 12.5 0.0 10 5.8 0.0 2.3 2 0 0 2 2 2 0 Alpha/beta hydrolase family BAAT_C PF08840.11 OQR96029.1 - 0.09 12.7 0.0 0.15 11.9 0.0 1.3 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal NIF3 PF01784.18 OQR96029.1 - 0.1 12.2 0.0 0.21 11.2 0.0 1.5 1 0 0 1 1 1 0 NIF3 (NGG1p interacting factor 3) Ank_2 PF12796.7 OQR96030.1 - 1.3e-18 67.3 13.6 7.5e-09 36.1 1.3 4.0 1 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OQR96030.1 - 1.2e-12 47.8 19.4 0.0048 17.2 0.2 7.5 2 1 6 8 8 8 6 Ankyrin repeats (many copies) Ank_4 PF13637.6 OQR96030.1 - 1.1e-11 45.0 14.8 1.2e-05 25.8 0.6 5.3 4 2 3 7 7 7 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQR96030.1 - 1.1e-10 40.8 8.7 0.22 12.2 0.0 8.0 6 1 2 8 8 8 2 Ankyrin repeat Ank PF00023.30 OQR96030.1 - 7e-05 23.1 7.0 7.5 7.2 0.1 6.8 5 3 1 6 6 6 1 Ankyrin repeat HA PF03457.14 OQR96030.1 - 0.0018 18.6 1.2 4.5 7.7 0.0 4.7 1 1 3 4 4 4 1 Helicase associated domain DUF2790 PF10976.8 OQR96030.1 - 0.094 12.7 0.7 18 5.4 0.1 3.7 2 2 2 4 4 4 0 Protein of unknown function (DUF2790) Got1 PF04178.12 OQR96031.1 - 2.1e-17 63.6 13.8 2.5e-17 63.3 13.8 1.1 1 0 0 1 1 1 1 Got1/Sft2-like family DUF2157 PF09925.9 OQR96031.1 - 0.13 12.0 7.2 0.19 11.5 7.2 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2157) DUF308 PF03729.13 OQR96031.1 - 0.19 12.1 16.7 0.05 13.9 9.8 2.2 1 1 1 2 2 2 0 Short repeat of unknown function (DUF308) MDM10 PF12519.8 OQR96031.1 - 0.3 9.9 0.0 0.31 9.9 0.0 1.0 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 DUF4418 PF14387.6 OQR96031.1 - 0.4 10.9 5.2 0.36 11.0 0.7 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4418) Gar1 PF04410.14 OQR96032.1 - 2.6e-35 121.5 0.0 3.5e-35 121.1 0.0 1.1 1 0 0 1 1 1 1 Gar1/Naf1 RNA binding region Tmemb_14 PF03647.13 OQR96032.1 - 1.5e-21 76.9 11.0 2.3e-21 76.3 11.0 1.3 1 0 0 1 1 1 1 Transmembrane proteins 14C Chromate_transp PF02417.15 OQR96032.1 - 0.046 13.8 1.8 0.079 13.1 1.8 1.3 1 0 0 1 1 1 0 Chromate transporter YabA PF06156.13 OQR96033.1 - 0.0011 19.6 4.1 0.11 13.2 1.8 2.8 2 0 0 2 2 2 2 Initiation control protein YabA PGAP1 PF07819.13 OQR96045.1 - 3.2e-05 23.8 0.4 0.00011 22.0 0.1 2.0 2 0 0 2 2 2 1 PGAP1-like protein LCAT PF02450.15 OQR96045.1 - 0.0088 15.2 0.0 0.024 13.8 0.0 1.7 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase Hydrolase_4 PF12146.8 OQR96045.1 - 0.04 13.2 0.0 0.11 11.7 0.0 1.7 1 0 0 1 1 1 0 Serine aminopeptidase, S33 TFB6 PF17110.5 OQR96045.1 - 4.3 7.1 6.7 0.34 10.6 1.4 1.8 2 0 0 2 2 2 0 Subunit 11 of the general transcription factor TFIIH MFS_1 PF07690.16 OQR96047.1 - 1.7e-23 83.1 65.8 3.7e-13 49.1 12.2 3.6 3 1 0 3 3 3 3 Major Facilitator Superfamily UNC-93 PF05978.16 OQR96047.1 - 1.5e-16 60.5 35.8 5.7e-10 39.1 8.0 6.1 5 1 0 5 5 5 4 Ion channel regulatory protein UNC-93 Pkinase PF00069.25 OQR96048.1 - 3.6e-84 282.2 0.0 3.1e-43 148.1 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OQR96048.1 - 1.8e-83 279.8 0.0 5e-41 140.7 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase EPL1 PF10513.9 OQR96048.1 - 0.041 14.3 0.1 0.083 13.3 0.1 1.4 1 0 0 1 1 1 0 Enhancer of polycomb-like IQ PF00612.27 OQR96049.1 - 1.8e-14 52.1 15.4 0.00022 20.7 0.4 4.8 4 0 0 4 4 4 4 IQ calmodulin-binding motif Herpes_IE2_3 PF03361.14 OQR96049.1 - 0.037 13.9 0.1 0.083 12.8 0.1 1.6 1 0 0 1 1 1 0 Herpes virus intermediate/early protein 2/3 Ank_2 PF12796.7 OQR96050.1 - 3.1e-67 223.1 1.5 6.8e-10 39.4 0.0 8.5 2 2 6 8 8 8 8 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQR96050.1 - 5.4e-56 186.3 8.4 1e-09 38.7 0.0 12.1 7 3 5 13 13 13 10 Ankyrin repeats (many copies) Ank_5 PF13857.6 OQR96050.1 - 5.9e-54 179.4 7.0 1.3e-08 34.9 0.0 11.3 7 3 3 11 11 11 10 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQR96050.1 - 3e-46 150.0 5.9 0.00038 20.7 0.0 16.0 16 0 0 16 16 16 7 Ankyrin repeat Ank PF00023.30 OQR96050.1 - 1.5e-31 107.5 28.0 0.0071 16.7 0.1 15.0 14 2 2 16 16 16 8 Ankyrin repeat PIN_10 PF18478.1 OQR96050.1 - 0.12 12.6 0.0 1.7 8.9 0.0 2.7 3 0 0 3 3 3 0 PIN like domain Rx_N PF18052.1 OQR96051.1 - 0.087 13.1 3.2 0.15 12.3 2.7 1.8 1 1 0 1 1 1 0 Rx N-terminal domain Dynein_C PF18199.1 OQR96052.1 - 2.4e-109 365.3 0.0 2.4e-109 365.3 0.0 2.0 2 0 0 2 2 2 1 Dynein heavy chain C-terminal domain AAA_9 PF12781.7 OQR96052.1 - 4e-89 297.5 0.9 2.6e-88 294.9 1.5 2.2 2 0 0 2 2 2 1 ATP-binding dynein motor region MT PF12777.7 OQR96052.1 - 3.3e-55 187.5 9.1 3.3e-55 187.5 9.1 1.6 2 0 0 2 2 2 1 Microtubule-binding stalk of dynein motor AAA_lid_11 PF18198.1 OQR96052.1 - 3.6e-54 183.0 0.0 7.5e-54 182.0 0.0 1.6 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_8 PF12780.7 OQR96052.1 - 1.2e-46 159.2 0.0 2.1e-46 158.4 0.0 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 Dynein_heavy PF03028.15 OQR96052.1 - 1.2e-46 157.7 0.0 1.2e-44 151.2 0.0 2.7 2 0 0 2 2 2 1 Dynein heavy chain region D6 P-loop domain Spc7 PF08317.11 OQR96052.1 - 0.00073 18.5 5.9 0.00073 18.5 5.9 2.4 2 0 0 2 2 2 1 Spc7 kinetochore protein Vps51 PF08700.11 OQR96052.1 - 0.018 15.1 3.7 0.29 11.2 1.0 2.9 2 0 0 2 2 2 0 Vps51/Vps67 TMF_TATA_bd PF12325.8 OQR96052.1 - 0.9 9.8 7.1 0.94 9.7 1.7 2.9 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding ADIP PF11559.8 OQR96052.1 - 1 9.4 9.4 4 7.5 3.7 2.5 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding Fez1 PF06818.15 OQR96052.1 - 7.7 6.9 11.3 35 4.8 0.1 2.5 2 0 0 2 2 2 0 Fez1 Methyltransf_16 PF10294.9 OQR96054.1 - 3.1e-25 88.9 0.0 4e-25 88.5 0.0 1.1 1 0 0 1 1 1 1 Lysine methyltransferase PrmA PF06325.13 OQR96054.1 - 0.0004 19.9 0.0 0.00059 19.3 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.6 OQR96054.1 - 0.00051 20.7 0.0 0.00082 20.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OQR96054.1 - 0.0049 16.7 0.0 0.0066 16.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain EF-hand_7 PF13499.6 OQR96055.1 - 0.0042 17.5 1.1 0.16 12.4 0.2 2.9 2 0 0 2 2 2 1 EF-hand domain pair Phage_TAC_13 PF16459.5 OQR96055.1 - 0.028 14.9 0.1 0.072 13.5 0.1 1.7 1 0 0 1 1 1 0 Phage tail assembly chaperone, TAC EppA_BapA PF07268.11 OQR96055.1 - 0.11 12.4 0.2 0.22 11.5 0.2 1.4 1 0 0 1 1 1 0 Exported protein precursor (EppA/BapA) Metallophos PF00149.28 OQR96062.1 - 1.9e-31 110.2 0.0 5.4e-06 27.1 0.1 5.8 4 4 0 4 4 4 4 Calcineurin-like phosphoesterase Sec23_trunk PF04811.15 OQR96062.1 - 0.56 9.7 1.7 46 3.5 0.1 3.2 3 0 0 3 3 3 0 Sec23/Sec24 trunk domain Hormone_2 PF00123.20 OQR96062.1 - 2.3 8.2 5.1 9.4 6.2 0.2 3.7 4 0 0 4 4 4 0 Peptide hormone Phage_30_3 PF08010.11 OQR96062.1 - 4.1 7.2 5.5 6.8 6.5 0.1 3.5 4 0 0 4 4 4 0 Bacteriophage protein GP30.3 Oxidored_q2 PF00420.24 OQR96062.1 - 5.4 6.7 7.3 12 5.6 0.3 3.9 4 1 0 4 4 4 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L Metallophos PF00149.28 OQR96063.1 - 3.4e-28 99.5 1.1 2e-09 38.3 0.1 4.8 4 2 0 4 4 4 3 Calcineurin-like phosphoesterase EphA2_TM PF14575.6 OQR96063.1 - 1.7e-05 25.6 0.0 0.95 10.4 0.0 3.3 3 0 0 3 3 3 2 Ephrin type-A receptor 2 transmembrane domain Phage_30_3 PF08010.11 OQR96063.1 - 8.2e-05 22.4 0.4 0.057 13.2 0.0 2.7 2 0 0 2 2 2 2 Bacteriophage protein GP30.3 DUF4064 PF13273.6 OQR96063.1 - 0.0035 17.6 0.6 13 6.1 0.0 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF4064) DUF4834 PF16118.5 OQR96063.1 - 0.0046 17.9 0.0 21 6.1 0.0 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4834) CwsA PF10814.8 OQR96063.1 - 0.02 15.0 6.4 4 7.6 0.2 3.3 3 0 0 3 3 3 0 Cell wall synthesis protein CwsA Trp_oprn_chp PF09534.10 OQR96063.1 - 0.039 13.8 9.6 3.6 7.3 0.5 3.4 3 0 0 3 3 3 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Claudin_2 PF13903.6 OQR96063.1 - 0.21 11.3 2.1 4.9 6.8 0.0 3.1 3 0 0 3 3 3 0 PMP-22/EMP/MP20/Claudin tight junction DUF4307 PF14155.6 OQR96063.1 - 0.28 11.0 9.5 7.9 6.4 0.2 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4307) Claudin_3 PF06653.11 OQR96063.1 - 0.3 11.0 1.5 4.7 7.1 0.0 2.9 3 0 0 3 3 3 0 Tight junction protein, Claudin-like DUF4330 PF14221.6 OQR96063.1 - 0.74 10.0 3.5 40 4.4 0.0 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4330) SP_C-Propep PF08999.10 OQR96063.1 - 1 9.2 4.8 5.8 6.8 0.0 3.1 3 0 0 3 3 3 0 Surfactant protein C, N terminal propeptide DUF5362 PF17319.2 OQR96063.1 - 2.7 7.9 7.1 5.5 6.9 0.2 3.1 3 0 0 3 3 3 0 Family of unknown function (DUF5362) GRA6 PF05084.13 OQR96063.1 - 5.7 6.8 8.7 7.9 6.4 0.1 2.7 3 0 0 3 3 2 0 Granule antigen protein (GRA6) Ank_4 PF13637.6 OQR96064.1 - 1.3e-13 51.2 7.7 0.00028 21.4 0.3 5.4 4 1 1 5 5 5 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 OQR96064.1 - 6.8e-12 45.8 5.1 3.7e-06 27.4 0.8 3.6 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OQR96064.1 - 8.2e-09 35.6 5.0 0.016 15.5 0.1 6.1 3 2 4 7 7 7 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQR96064.1 - 3.4e-08 33.1 4.9 3.4 8.5 0.0 6.4 7 0 0 7 7 7 3 Ankyrin repeat DUF5049 PF16468.5 OQR96064.1 - 0.0019 18.0 0.2 4.1 7.4 0.0 4.2 4 1 1 5 5 5 1 Domain of unknown function (DUF5049) Ank PF00023.30 OQR96064.1 - 0.077 13.5 7.4 29 5.3 0.4 5.0 4 2 0 4 4 4 0 Ankyrin repeat Sen15 PF09631.10 OQR96065.1 - 0.011 16.1 0.0 0.014 15.6 0.0 1.2 1 0 0 1 1 1 0 Sen15 protein Carn_acyltransf PF00755.20 OQR96066.1 - 3.8e-175 583.9 0.0 6.7e-175 583.1 0.0 1.3 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase AAA PF00004.29 OQR96066.1 - 1.5e-39 135.4 0.0 4.2e-39 134.0 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 OQR96066.1 - 4.8e-09 36.0 0.1 9.8e-09 35.0 0.1 1.6 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_lid_3 PF17862.1 OQR96066.1 - 1.1e-08 34.7 0.1 3.2e-08 33.2 0.1 1.8 1 0 0 1 1 1 1 AAA+ lid domain AAA_22 PF13401.6 OQR96066.1 - 3e-05 24.3 0.2 0.0088 16.3 0.2 3.0 1 1 0 1 1 1 1 AAA domain AAA_2 PF07724.14 OQR96066.1 - 4.4e-05 23.7 0.0 0.00013 22.1 0.0 1.8 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.13 OQR96066.1 - 0.00011 21.4 0.0 0.00022 20.5 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_5 PF07728.14 OQR96066.1 - 0.00042 20.3 0.0 0.0019 18.2 0.0 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 OQR96066.1 - 0.00099 19.5 0.2 0.0085 16.5 0.1 2.4 1 1 1 2 2 2 1 AAA ATPase domain bZIP_1 PF00170.21 OQR96066.1 - 0.0069 16.5 9.1 0.0069 16.5 9.1 3.0 3 0 0 3 3 2 1 bZIP transcription factor RuvB_N PF05496.12 OQR96066.1 - 0.0077 16.0 0.0 0.016 15.0 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain RNA_helicase PF00910.22 OQR96066.1 - 0.046 14.1 0.0 0.12 12.8 0.0 1.7 1 0 0 1 1 1 0 RNA helicase IstB_IS21 PF01695.17 OQR96066.1 - 0.048 13.4 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein ATPase PF06745.13 OQR96066.1 - 0.054 12.8 0.0 0.45 9.8 0.0 2.3 2 0 0 2 2 2 0 KaiC TIP49 PF06068.13 OQR96066.1 - 0.099 11.8 0.0 0.18 11.0 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_3 PF07726.11 OQR96066.1 - 0.11 12.3 0.0 0.33 10.8 0.0 1.8 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Hamartin PF04388.12 OQR96066.1 - 0.14 10.8 13.0 0.22 10.1 13.0 1.2 1 0 0 1 1 1 0 Hamartin protein Aldedh PF00171.22 OQR96067.1 - 4.8e-136 453.9 0.0 5.4e-136 453.8 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family RRF PF01765.19 OQR96067.1 - 0.025 14.5 1.2 0.05 13.6 1.2 1.4 1 0 0 1 1 1 0 Ribosome recycling factor LuxC PF05893.14 OQR96067.1 - 0.07 12.2 0.0 0.12 11.4 0.0 1.4 1 0 0 1 1 1 0 Acyl-CoA reductase (LuxC) Thioredoxin PF00085.20 OQR96111.1 - 9.4e-18 64.1 0.0 1.1e-17 63.9 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 OQR96111.1 - 0.00029 21.2 0.2 0.0067 16.9 0.2 2.1 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_9 PF14595.6 OQR96111.1 - 0.019 14.7 0.0 0.023 14.5 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin Thioredoxin_8 PF13905.6 OQR96111.1 - 0.17 12.3 0.0 0.44 10.9 0.0 1.7 1 1 1 2 2 2 0 Thioredoxin-like Sec7 PF01369.20 OQR96112.1 - 4.5e-64 215.5 0.0 7.6e-64 214.8 0.0 1.4 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.7 OQR96112.1 - 2.4e-30 105.5 4.0 2.4e-30 105.5 4.0 3.0 2 0 0 2 2 2 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DCB PF16213.5 OQR96112.1 - 4.1e-06 26.6 0.3 1.2e-05 25.0 0.3 1.9 1 0 0 1 1 1 1 Dimerisation and cyclophilin-binding domain of Mon2 MBOAT PF03062.19 OQR96113.1 - 2.3e-38 132.4 9.1 4.8e-38 131.4 9.1 1.5 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family Pkinase PF00069.25 OQR96115.1 - 1.9e-42 145.5 0.0 2.3e-42 145.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQR96115.1 - 2e-12 46.9 0.0 2.7e-12 46.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OQR96115.1 - 1.2e-05 24.4 0.0 1.8e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 OQR96115.1 - 0.00044 19.7 0.0 0.00073 18.9 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 OQR96115.1 - 0.014 14.7 0.0 0.02 14.2 0.0 1.2 1 0 0 1 1 1 0 Kinase-like YrbL-PhoP_reg PF10707.9 OQR96115.1 - 0.015 14.8 0.0 0.031 13.8 0.0 1.4 1 1 0 1 1 1 0 PhoP regulatory network protein YrbL Metallophos PF00149.28 OQR96116.1 - 0.0006 20.4 5.9 0.05 14.1 6.0 2.8 1 1 1 2 2 2 1 Calcineurin-like phosphoesterase SURNod19 PF07712.12 OQR96117.1 - 2.8e-15 56.0 0.1 4.9e-15 55.2 0.1 1.3 1 1 0 1 1 1 1 Stress up-regulated Nod 19 Actin PF00022.19 OQR96118.1 - 7.8e-86 288.2 0.1 1.8e-78 264.0 0.0 2.9 1 1 1 2 2 2 2 Actin Peptidase_C1 PF00112.23 OQR96119.1 - 8.3e-42 143.7 1.2 1.2e-41 143.2 1.2 1.3 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.15 OQR96119.1 - 0.017 13.9 0.1 0.025 13.4 0.1 1.1 1 0 0 1 1 1 0 Peptidase C1-like family Q_salvage PF10343.9 OQR96122.1 - 1.8e-76 257.4 0.0 2.6e-76 256.9 0.0 1.2 1 0 0 1 1 1 1 Potential Queuosine, Q, salvage protein family AMP-binding PF00501.28 OQR96123.1 - 8.7e-84 281.5 0.0 1.2e-83 281.1 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Hexapep PF00132.24 OQR96123.1 - 4.5e-07 29.3 12.0 0.03 14.1 0.2 5.9 6 1 0 6 6 6 3 Bacterial transferase hexapeptide (six repeats) AMP-binding_C PF13193.6 OQR96123.1 - 0.00092 20.1 0.0 0.0023 18.9 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain PP-binding PF00550.25 OQR96123.1 - 0.12 12.7 0.0 0.42 11.0 0.0 1.9 1 0 0 1 1 1 0 Phosphopantetheine attachment site Hexapep_2 PF14602.6 OQR96123.1 - 2.7 7.8 20.3 0.18 11.6 1.4 5.9 6 1 0 6 6 6 0 Hexapeptide repeat of succinyl-transferase DUF1326 PF07040.11 OQR96124.1 - 0.21 11.6 0.1 0.33 11.0 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1326) Ion_trans PF00520.31 OQR96124.1 - 0.72 9.0 10.6 0.18 11.0 1.0 3.0 2 1 1 3 3 3 0 Ion transport protein Ank_2 PF12796.7 OQR96179.1 - 1.5e-22 80.0 13.8 4.5e-10 40.0 0.2 4.4 1 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQR96179.1 - 5.1e-19 68.4 14.1 0.00031 21.3 0.1 6.3 4 1 1 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQR96179.1 - 1.1e-17 62.3 9.8 0.073 13.7 0.0 8.5 7 1 1 8 8 8 6 Ankyrin repeat Ank_5 PF13857.6 OQR96179.1 - 5.8e-15 55.2 18.8 0.093 13.1 0.1 8.7 2 2 7 9 9 9 6 Ankyrin repeats (many copies) Ank PF00023.30 OQR96179.1 - 2.6e-05 24.4 11.2 0.12 12.9 0.0 6.3 4 2 1 5 5 5 1 Ankyrin repeat YmaF PF12788.7 OQR96179.1 - 0.026 15.0 4.0 0.22 12.1 3.2 2.6 1 1 2 3 3 3 0 YmaF family UPF0180 PF03698.13 OQR96179.1 - 0.095 12.9 0.0 22 5.3 0.0 2.6 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0180) SAM_1 PF00536.30 OQR96180.1 - 1.5e-13 51.0 0.1 4e-13 49.6 0.1 1.8 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Ank_5 PF13857.6 OQR96180.1 - 6.5e-13 48.6 0.3 2e-08 34.3 0.0 2.7 1 1 1 2 2 2 2 Ankyrin repeats (many copies) SAM_2 PF07647.17 OQR96180.1 - 5.5e-09 36.0 0.1 2.2e-08 34.1 0.1 2.0 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) IQ PF00612.27 OQR96180.1 - 1.1e-08 34.1 21.3 0.062 13.1 0.0 6.4 6 0 0 6 6 6 5 IQ calmodulin-binding motif Ank_4 PF13637.6 OQR96180.1 - 5.6e-08 33.2 0.0 0.00017 22.1 0.0 3.7 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 OQR96180.1 - 1.8e-07 31.6 0.3 5e-07 30.2 0.0 1.9 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank PF00023.30 OQR96180.1 - 6.2e-07 29.6 0.1 0.056 13.9 0.0 2.9 2 0 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.6 OQR96180.1 - 5.7e-05 23.2 0.0 0.55 11.0 0.0 3.0 2 0 0 2 2 2 2 Ankyrin repeat FAD_binding_5 PF00941.21 OQR96180.1 - 0.26 11.0 2.9 1 9.0 1.6 2.5 2 0 0 2 2 2 0 FAD binding domain in molybdopterin dehydrogenase Bromodomain PF00439.25 OQR96181.1 - 1e-36 124.8 0.0 4.3e-17 61.9 0.0 2.9 2 0 0 2 2 2 2 Bromodomain WSD PF15613.6 OQR96181.1 - 3.9e-11 43.3 6.6 5.8e-10 39.5 0.6 3.4 2 1 0 2 2 2 1 Williams-Beuren syndrome DDT (WSD), D-TOX E motif DNMT1-RFD PF12047.8 OQR96181.1 - 0.012 15.6 0.3 0.032 14.3 0.0 1.9 2 0 0 2 2 2 0 Cytosine specific DNA methyltransferase replication foci domain Auxin_resp PF06507.13 OQR96181.1 - 0.049 13.9 0.0 0.14 12.4 0.0 1.7 1 0 0 1 1 1 0 Auxin response factor AT_hook PF02178.19 OQR96181.1 - 0.21 11.6 2.7 0.49 10.4 2.7 1.7 1 0 0 1 1 1 0 AT hook motif HGTP_anticodon PF03129.20 OQR96182.1 - 1.3e-20 73.4 0.0 2.5e-20 72.4 0.0 1.5 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2b PF00587.25 OQR96182.1 - 1.1e-10 41.8 0.0 1.8e-10 41.0 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Zn-ribbon_8 PF09723.10 OQR96182.1 - 0.0043 17.1 0.6 3.3 7.9 0.1 2.5 2 0 0 2 2 2 2 Zinc ribbon domain zinc_ribbon_15 PF17032.5 OQR96182.1 - 0.028 15.1 0.3 0.074 13.8 0.3 1.7 1 0 0 1 1 1 0 zinc-ribbon family DZR PF12773.7 OQR96182.1 - 0.099 12.7 0.4 0.26 11.3 0.4 1.7 1 0 0 1 1 1 0 Double zinc ribbon DUF1178 PF06676.11 OQR96182.1 - 0.13 12.6 0.0 0.25 11.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1178) zf-ribbon_3 PF13248.6 OQR96182.1 - 0.19 11.2 0.9 1.2 8.6 0.1 2.3 2 0 0 2 2 2 0 zinc-ribbon domain DNA_RNApol_7kD PF03604.13 OQR96182.1 - 0.34 10.6 1.6 5.8 6.7 0.1 2.5 2 0 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit MFS_1_like PF12832.7 OQR96183.1 - 6.9e-67 226.0 25.7 1.1e-66 225.3 25.7 1.3 1 1 0 1 1 1 1 MFS_1 like family MFS_1 PF07690.16 OQR96183.1 - 1.8e-29 102.8 50.9 1e-21 77.3 30.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Nuc_H_symport PF03825.16 OQR96183.1 - 1.3e-14 54.0 19.7 2.4e-14 53.1 19.7 1.4 1 1 0 1 1 1 1 Nucleoside H+ symporter LacY_symp PF01306.19 OQR96183.1 - 9.4e-12 44.4 17.5 1.3e-11 43.9 17.5 1.1 1 0 0 1 1 1 1 LacY proton/sugar symporter MFS_2 PF13347.6 OQR96183.1 - 1.1e-07 30.8 27.9 0.00079 18.1 10.7 2.3 1 1 1 2 2 2 2 MFS/sugar transport protein MFS_3 PF05977.13 OQR96183.1 - 0.0013 17.2 11.7 0.0045 15.4 11.7 1.8 1 1 0 1 1 1 1 Transmembrane secretion effector UNC-93 PF05978.16 OQR96183.1 - 0.0042 16.8 2.1 0.0042 16.8 2.1 2.3 2 1 0 2 2 2 1 Ion channel regulatory protein UNC-93 CDP-OH_P_tran_2 PF08009.11 OQR96183.1 - 5.9 6.9 9.6 1.1 9.2 0.4 2.9 2 0 0 2 2 2 0 CDP-alcohol phosphatidyltransferase 2 Tcf25 PF04910.14 OQR96184.1 - 2.9e-69 233.8 0.1 5.1e-69 233.0 0.1 1.3 1 0 0 1 1 1 1 Transcriptional repressor TCF25 DUF1336 PF07059.12 OQR96184.1 - 5.1e-52 177.2 0.0 1.1e-51 176.1 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1336) DUF2054 PF10218.9 OQR96184.1 - 5e-29 101.1 19.7 1.2e-28 99.9 19.7 1.7 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2054) MFS_1 PF07690.16 OQR96184.1 - 1.4e-28 99.9 35.3 2.3e-28 99.1 35.3 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Ricin_B_lectin PF00652.22 OQR96184.1 - 1.2e-16 61.1 6.5 8.4e-12 45.4 2.3 2.5 2 0 0 2 2 2 2 Ricin-type beta-trefoil lectin domain Sugar_tr PF00083.24 OQR96184.1 - 2.8e-13 49.5 24.2 5.5e-13 48.6 24.2 1.4 1 0 0 1 1 1 1 Sugar (and other) transporter CDtoxinA PF03498.14 OQR96184.1 - 7.1e-07 28.9 1.6 0.031 13.9 0.4 2.4 2 0 0 2 2 2 2 Cytolethal distending toxin A/C domain RicinB_lectin_2 PF14200.6 OQR96184.1 - 0.018 15.7 8.2 0.067 13.9 2.3 3.1 2 0 0 2 2 2 0 Ricin-type beta-trefoil lectin domain-like Herpes_DNAp_acc PF04929.12 OQR96184.1 - 0.082 11.9 4.7 0.14 11.1 4.7 1.2 1 0 0 1 1 1 0 Herpes DNA replication accessory factor SR-25 PF10500.9 OQR96184.1 - 0.28 10.7 10.8 0.5 9.9 10.8 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein SPT6_acidic PF14632.6 OQR96184.1 - 0.67 10.6 6.8 1.4 9.6 6.8 1.4 1 0 0 1 1 1 0 Acidic N-terminal SPT6 Ribosomal_60s PF00428.19 OQR96184.1 - 0.76 10.4 9.3 2.5 8.7 9.3 1.9 1 0 0 1 1 1 0 60s Acidic ribosomal protein PRCC PF10253.9 OQR96184.1 - 0.83 10.4 9.0 1.8 9.3 9.0 1.5 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting eIF3_subunit PF08597.10 OQR96184.1 - 1.5 8.6 14.4 2.7 7.9 14.4 1.3 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit MFS_1_like PF12832.7 OQR96185.1 - 3.3e-61 207.3 18.7 4.9e-61 206.7 18.7 1.2 1 0 0 1 1 1 1 MFS_1 like family MFS_1 PF07690.16 OQR96185.1 - 7.5e-22 77.7 52.8 4.9e-17 61.9 30.0 2.8 1 1 1 2 2 2 2 Major Facilitator Superfamily Nuc_H_symport PF03825.16 OQR96185.1 - 5.7e-13 48.6 13.2 1.1e-12 47.7 13.2 1.3 1 1 0 1 1 1 1 Nucleoside H+ symporter LacY_symp PF01306.19 OQR96185.1 - 4.6e-11 42.2 13.8 7.9e-11 41.4 13.8 1.3 1 1 0 1 1 1 1 LacY proton/sugar symporter MFS_3 PF05977.13 OQR96185.1 - 7.1e-10 37.9 8.0 1.1e-09 37.3 8.0 1.2 1 0 0 1 1 1 1 Transmembrane secretion effector PUCC PF03209.15 OQR96185.1 - 1.6 7.6 14.9 0.015 14.3 3.5 2.8 3 1 0 3 3 3 0 PUCC protein Hexapep PF00132.24 OQR96188.1 - 1.4e-09 37.3 5.1 7.6e-06 25.4 0.1 3.8 3 1 1 4 4 4 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 OQR96188.1 - 3.3e-05 23.5 4.3 0.03 14.1 0.2 3.6 3 0 0 3 3 3 2 Hexapeptide repeat of succinyl-transferase PPPI_inhib PF14895.6 OQR96189.1 - 0.0002 20.7 0.0 0.00031 20.0 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 1 inhibitor Csc2 PF18320.1 OQR96189.1 - 0.025 13.5 0.0 0.033 13.2 0.0 1.1 1 0 0 1 1 1 0 Csc2 Crispr DUF1699 PF08004.11 OQR96189.1 - 0.099 12.3 0.0 0.18 11.5 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1699) Kinesin PF00225.23 OQR96191.1 - 2e-90 303.1 1.5 2e-90 303.1 1.5 2.1 2 1 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 OQR96191.1 - 5.1e-36 123.8 0.0 2.3e-35 121.7 0.0 2.3 1 0 0 1 1 1 1 Microtubule binding PDZ PF00595.24 OQR96191.1 - 1.7e-12 47.5 0.0 2.8e-05 24.4 0.0 4.1 4 0 0 4 4 4 2 PDZ domain PDZ_6 PF17820.1 OQR96191.1 - 1.3e-06 28.1 0.3 0.43 10.5 0.0 4.2 4 0 0 4 4 4 3 PDZ domain Apolipoprotein PF01442.18 OQR96191.1 - 3.3e-05 23.8 22.9 3.3e-05 23.8 22.9 4.2 3 1 1 4 4 4 2 Apolipoprotein A1/A4/E domain Baculo_PEP_C PF04513.12 OQR96191.1 - 0.36 10.9 39.3 1.4 9.0 19.0 4.4 3 1 1 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF4407 PF14362.6 OQR96191.1 - 0.51 9.7 37.2 0.88 8.9 25.7 3.5 2 1 1 3 3 3 0 Domain of unknown function (DUF4407) ArdA PF07275.11 OQR96191.1 - 4.9 7.7 6.3 0.99 10.0 1.0 2.4 2 0 0 2 2 2 0 Antirestriction protein (ArdA) Phage_Mu_Gam PF07352.12 OQR96191.1 - 5.9 6.8 27.1 0.59 10.0 0.2 5.3 2 1 2 5 5 5 0 Bacteriophage Mu Gam like protein ApoO PF09769.9 OQR96191.1 - 9.4 6.2 13.7 2.8 7.9 0.7 4.0 3 0 0 3 3 3 0 Apolipoprotein O Pep3_Vps18 PF05131.14 OQR96192.1 - 5.6e-36 123.6 0.0 5e-35 120.5 0.0 2.5 2 0 0 2 2 2 1 Pep3/Vps18/deep orange family Clathrin PF00637.20 OQR96192.1 - 4.7e-09 36.2 14.3 7.1e-08 32.4 0.5 4.2 4 2 0 4 4 4 2 Region in Clathrin and VPS Vps39_2 PF10367.9 OQR96192.1 - 0.002 18.5 0.2 0.095 13.2 0.0 3.0 2 1 0 2 2 2 1 Vacuolar sorting protein 39 domain 2 TPR_16 PF13432.6 OQR96192.1 - 0.019 15.6 1.6 0.14 12.9 1.3 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.6 OQR96192.1 - 0.048 13.7 7.9 0.3 11.2 0.3 4.4 4 1 0 4 4 4 0 Tetratricopeptide repeat ECH_2 PF16113.5 OQR96192.1 - 0.054 13.0 0.2 0.15 11.5 0.2 1.8 1 0 0 1 1 1 0 Enoyl-CoA hydratase/isomerase TPR_14 PF13428.6 OQR96192.1 - 0.095 13.6 1.7 8.6 7.5 0.5 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat zf-RING_11 PF17123.5 OQR96192.1 - 0.11 12.3 0.3 0.29 10.9 0.3 1.7 1 0 0 1 1 1 0 RING-like zinc finger TPR_8 PF13181.6 OQR96192.1 - 0.33 11.3 3.5 3.6 8.0 0.1 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.17 OQR96192.1 - 0.42 10.9 6.4 0.21 11.8 0.4 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.28 OQR96192.1 - 1.4 8.9 5.3 4.6 7.2 0.4 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat Myb_DNA-binding PF00249.31 OQR96193.1 - 1.4e-44 150.0 9.4 4.9e-15 55.5 0.8 3.3 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OQR96193.1 - 1.3e-34 118.2 6.2 1.5e-13 50.7 0.3 3.3 2 1 1 3 3 3 3 Myb-like DNA-binding domain SLIDE PF09111.10 OQR96193.1 - 2.4e-08 34.0 0.1 0.0078 16.2 0.0 3.3 1 1 2 3 3 3 3 SLIDE Myb_DNA-bind_7 PF15963.5 OQR96193.1 - 5.1e-07 29.5 0.8 0.041 13.8 0.0 3.1 1 1 2 3 3 3 2 Myb DNA-binding like SANT_DAMP1_like PF16282.5 OQR96193.1 - 2.2e-06 27.8 2.3 0.056 13.6 0.1 3.5 1 1 2 3 3 3 2 SANT/Myb-like domain of DAMP1 Nore1-SARAH PF16517.5 OQR96193.1 - 0.021 14.7 0.0 0.58 10.1 0.0 2.3 2 0 0 2 2 2 0 Novel Ras effector 1 C-terminal SARAH (Sav/Rassf/Hpo) domain Myb_DNA-bind_4 PF13837.6 OQR96193.1 - 0.035 14.5 9.2 2.1 8.8 1.1 3.7 2 1 1 3 3 3 0 Myb/SANT-like DNA-binding domain DUF3395 PF11875.8 OQR96194.1 - 4.2e-10 39.7 0.0 0.0051 16.7 0.0 3.4 3 0 0 3 3 3 3 Domain of unknown function (DUF3395) Gal_Lectin PF02140.18 OQR96194.1 - 3.1e-07 30.7 0.1 1.5 9.3 0.0 4.7 4 1 0 4 4 4 3 Galactose binding lectin domain Pedibin PF08182.11 OQR96194.1 - 0.16 11.8 2.9 0.44 10.4 2.9 1.7 1 0 0 1 1 1 0 Pedibin/Hym-346 family RCC1 PF00415.18 OQR96195.1 - 2.6e-56 188.0 21.6 2.6e-12 47.2 0.4 8.5 8 1 0 8 8 8 8 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 OQR96195.1 - 5.5e-23 80.2 34.9 4.1e-06 26.4 0.5 7.8 8 0 0 8 8 8 6 Regulator of chromosome condensation (RCC1) repeat SAP PF02037.27 OQR96195.1 - 0.019 14.7 0.9 0.035 13.9 0.9 1.5 1 0 0 1 1 1 0 SAP domain TMEM208_SND2 PF05620.11 OQR96196.1 - 6.6e-18 65.0 0.1 7.7e-18 64.8 0.1 1.2 1 0 0 1 1 1 1 SRP-independent targeting protein 2/TMEM208 PKD_channel PF08016.12 OQR96197.1 - 4.3e-24 85.0 7.8 2.3e-23 82.6 4.3 2.9 2 1 1 3 3 3 2 Polycystin cation channel DDE_Tnp_4 PF13359.6 OQR96198.1 - 1e-25 90.2 0.0 1.4e-25 89.8 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 OQR96198.1 - 3.2e-09 36.7 0.2 3e-08 33.5 0.2 2.0 1 1 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 OQR96198.1 - 4.7e-07 29.7 0.1 2.3e-06 27.4 0.1 1.9 1 1 0 1 1 1 1 Transposase DDE domain Cyclin_N PF00134.23 OQR96268.1 - 4.8e-43 145.9 2.0 1.8e-38 131.1 0.0 3.9 2 1 0 3 3 3 3 Cyclin, N-terminal domain Cyclin_C PF02984.19 OQR96268.1 - 4.9e-26 91.2 0.8 1.2e-25 89.9 0.8 1.7 1 0 0 1 1 1 1 Cyclin, C-terminal domain SCP2 PF02036.17 OQR96268.1 - 0.045 14.2 0.0 0.64 10.6 0.0 2.5 2 0 0 2 2 2 0 SCP-2 sterol transfer family Anoctamin PF04547.12 OQR96269.1 - 1.4e-72 244.9 16.4 2.5e-72 244.1 16.4 1.4 1 0 0 1 1 1 1 Calcium-activated chloride channel WD40 PF00400.32 OQR96269.1 - 7.8e-07 29.7 5.6 0.81 10.7 0.0 5.3 5 0 0 5 5 5 3 WD domain, G-beta repeat Ge1_WD40 PF16529.5 OQR96269.1 - 0.006 15.6 0.4 6 5.7 0.2 3.3 4 0 0 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein ANAPC4_WD40 PF12894.7 OQR96269.1 - 0.0069 16.7 0.0 3.5 8.0 0.0 3.2 2 1 1 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain PQQ_3 PF13570.6 OQR96269.1 - 0.029 14.9 0.1 1.9 9.1 0.0 3.3 3 0 0 3 3 3 0 PQQ-like domain PQQ PF01011.21 OQR96269.1 - 0.14 12.1 0.4 0.52 10.3 0.2 2.1 2 0 0 2 2 2 0 PQQ enzyme repeat Sad1_UNC PF07738.13 OQR96271.1 - 1.5e-30 105.9 0.0 2.7e-30 105.1 0.0 1.4 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal Pkinase PF00069.25 OQR96271.1 - 1.5e-29 103.2 0.0 2.9e-29 102.2 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQR96271.1 - 1.4e-11 44.2 0.1 1.2e-10 41.2 0.0 2.3 2 1 0 2 2 2 1 Protein tyrosine kinase Seadorna_VP7 PF07387.11 OQR96271.1 - 0.0068 15.5 0.2 0.031 13.3 0.0 2.0 2 0 0 2 2 2 1 Seadornavirus VP7 APH PF01636.23 OQR96271.1 - 0.028 14.3 0.1 0.059 13.3 0.1 1.5 1 1 0 1 1 1 0 Phosphotransferase enzyme family DUF4618 PF15397.6 OQR96271.1 - 0.12 11.8 10.9 0.098 12.1 9.6 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4618) MnmE_helical PF12631.7 OQR96271.1 - 0.53 10.4 3.3 0.96 9.6 3.3 1.3 1 0 0 1 1 1 0 MnmE helical domain GAF PF01590.26 OQR96272.1 - 2e-33 115.8 0.0 2e-17 64.1 0.0 2.2 2 0 0 2 2 2 2 GAF domain GAF_2 PF13185.6 OQR96272.1 - 7.1e-24 84.7 0.0 2.8e-13 50.3 0.0 2.2 2 0 0 2 2 2 2 GAF domain GAF_3 PF13492.6 OQR96272.1 - 7e-18 65.2 0.0 1.9e-10 41.2 0.0 2.4 2 0 0 2 2 2 2 GAF domain dCache_1 PF02743.18 OQR96272.1 - 0.004 17.0 0.3 0.86 9.3 0.1 2.4 1 1 1 2 2 2 2 Cache domain Pkinase PF00069.25 OQR96273.1 - 8.3e-57 192.5 0.0 1.3e-56 191.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQR96273.1 - 9.3e-36 123.4 0.0 1.5e-35 122.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase HEAT PF02985.22 OQR96273.1 - 0.0001 22.2 0.6 0.34 11.3 0.1 3.4 2 0 0 2 2 2 2 HEAT repeat Kinase-like PF14531.6 OQR96273.1 - 0.0026 17.1 0.0 0.0056 16.0 0.0 1.5 1 0 0 1 1 1 1 Kinase-like HEAT_2 PF13646.6 OQR96273.1 - 0.035 14.5 0.0 0.14 12.6 0.0 2.1 1 1 0 1 1 1 0 HEAT repeats Arm PF00514.23 OQR96273.1 - 0.093 12.8 2.4 0.62 10.2 0.1 2.9 2 0 0 2 2 2 0 Armadillo/beta-catenin-like repeat Adaptin_N PF01602.20 OQR96273.1 - 0.27 9.7 3.1 11 4.4 0.2 3.1 2 1 1 3 3 3 0 Adaptin N terminal region Abhydrolase_3 PF07859.13 OQR96282.1 - 4.9e-38 131.1 0.0 3.4e-37 128.4 0.0 1.9 2 0 0 2 2 2 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 OQR96282.1 - 4.5e-27 94.9 0.0 2.1e-26 92.7 0.0 1.8 2 0 0 2 2 2 1 Steryl acetyl hydrolase Hydrolase_4 PF12146.8 OQR96282.1 - 0.00023 20.5 0.0 0.00043 19.6 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 COesterase PF00135.28 OQR96282.1 - 0.24 10.2 0.0 12 4.6 0.0 2.1 2 0 0 2 2 2 0 Carboxylesterase family Pyridoxal_deC PF00282.19 OQR96283.1 - 2.7e-23 82.3 0.0 1e-22 80.4 0.0 1.8 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.19 OQR96283.1 - 0.0007 18.7 0.0 0.001 18.1 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V SelA PF03841.13 OQR96283.1 - 0.013 14.5 0.0 0.022 13.8 0.0 1.3 1 0 0 1 1 1 0 L-seryl-tRNA selenium transferase DUF373 PF04123.13 OQR96284.1 - 2.1 7.7 12.8 2.7 7.4 12.6 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF373) Peptidase_C1_2 PF03051.15 OQR96286.1 - 5.5e-66 223.1 0.0 6.6e-66 222.9 0.0 1.0 1 0 0 1 1 1 1 Peptidase C1-like family Peptidase_C1_2 PF03051.15 OQR96287.1 - 7.7e-18 64.5 0.0 7.7e-18 64.5 0.0 1.0 1 0 0 1 1 1 1 Peptidase C1-like family Peptidase_C1 PF00112.23 OQR96287.1 - 0.00046 20.3 0.0 0.00049 20.3 0.0 1.1 1 0 0 1 1 1 1 Papain family cysteine protease COG6 PF06419.11 OQR96288.1 - 9.2e-18 63.8 0.1 9.2e-18 63.8 0.1 2.1 2 0 0 2 2 2 1 Conserved oligomeric complex COG6 DUF4207 PF13904.6 OQR96288.1 - 0.00013 21.8 15.8 0.00013 21.8 15.8 2.6 2 1 0 2 2 2 1 Domain of unknown function (DUF4207) tRNA-synt_1 PF00133.22 OQR96290.1 - 4.3e-159 530.6 0.1 7.1e-159 529.9 0.1 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 OQR96290.1 - 9.8e-22 77.5 0.2 2.1e-21 76.5 0.2 1.5 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 OQR96290.1 - 1.1e-17 63.9 3.3 1.7e-09 37.0 0.0 4.5 5 1 0 5 5 5 3 tRNA synthetases class I (M) 2OG-FeII_Oxy_3 PF13640.6 OQR96290.1 - 3.5e-06 27.8 0.0 0.01 16.7 0.0 2.9 2 0 0 2 2 2 2 2OG-Fe(II) oxygenase superfamily tRNA-synt_1e PF01406.19 OQR96290.1 - 4.3e-05 23.0 0.0 0.012 15.0 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain zf-FPG_IleRS PF06827.14 OQR96290.1 - 0.00071 19.4 1.4 0.0016 18.3 1.4 1.6 1 0 0 1 1 1 1 Zinc finger found in FPG and IleRS Pilin_PilA PF14245.6 OQR96290.1 - 0.015 15.3 0.0 0.045 13.8 0.0 1.8 1 0 0 1 1 1 0 Type IV pilin PilA tRNA-synt_1_2 PF13603.6 OQR96290.1 - 0.018 14.6 0.1 0.037 13.5 0.1 1.4 1 0 0 1 1 1 0 Leucyl-tRNA synthetase, Domain 2 Bacillus_HBL PF05791.11 OQR96290.1 - 0.03 14.1 1.3 0.18 11.6 0.0 2.6 3 0 0 3 3 3 0 Bacillus haemolytic enterotoxin (HBL) MCC-bdg_PDZ PF10506.9 OQR96290.1 - 0.049 13.6 1.7 0.12 12.4 1.7 1.6 1 0 0 1 1 1 0 PDZ domain of MCC-2 bdg protein for Usher syndrome Say1_Mug180 PF10340.9 OQR96291.1 - 0.0053 15.7 0.1 0.021 13.7 0.1 1.8 1 1 0 1 1 1 1 Steryl acetyl hydrolase Far-17a_AIG1 PF04750.14 OQR96292.1 - 0.0038 16.6 23.6 0.12 11.6 23.6 2.6 1 1 0 1 1 1 1 FAR-17a/AIG1-like protein Tmemb_18A PF09771.9 OQR96292.1 - 0.061 13.7 3.9 0.19 12.1 3.9 1.8 1 0 0 1 1 1 0 Transmembrane protein 188 MTABC_N PF16185.5 OQR96292.1 - 0.19 11.2 14.9 0.051 13.1 11.1 1.9 1 1 0 1 1 1 0 Mitochondrial ABC-transporter N-terminal five TM region WBP-1 PF11669.8 OQR96292.1 - 0.28 11.9 9.1 1.8 9.2 0.7 2.7 2 1 1 3 3 3 0 WW domain-binding protein 1 Arb2 PF09757.9 OQR96293.1 - 0.0053 15.9 0.0 0.89 8.6 0.0 2.1 1 1 0 2 2 2 2 Arb2 domain BTRD1 PF17660.1 OQR96293.1 - 0.17 11.7 0.0 0.33 10.8 0.0 1.4 1 0 0 1 1 1 0 Bacterial tandem repeat domain 1 WD40 PF00400.32 OQR96298.1 - 8.5e-49 162.5 18.9 2.1e-06 28.3 0.0 11.2 11 0 0 11 11 11 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OQR96298.1 - 6.9e-19 67.9 0.5 0.00012 22.3 0.1 7.5 4 3 4 8 8 8 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 OQR96298.1 - 4.7e-10 39.7 0.2 0.028 14.3 0.0 4.7 2 1 3 5 5 5 3 Eukaryotic translation initiation factor eIF2A PD40 PF07676.12 OQR96298.1 - 4.3e-05 23.3 3.1 20 5.2 0.0 6.4 7 0 0 7 7 7 0 WD40-like Beta Propeller Repeat Ge1_WD40 PF16529.5 OQR96298.1 - 0.00028 20.0 0.0 1.4 7.8 0.0 4.2 3 1 1 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 OQR96298.1 - 0.0013 17.5 0.1 0.0083 14.8 0.1 2.2 2 0 0 2 2 2 1 Nucleoporin Nup120/160 WD40_like PF17005.5 OQR96298.1 - 0.0039 16.6 0.0 2 7.7 0.0 3.0 3 0 0 3 3 3 2 WD40-like domain Nbas_N PF15492.6 OQR96298.1 - 0.02 14.3 0.5 14 4.9 0.0 3.8 3 1 1 4 4 4 0 Neuroblastoma-amplified sequence, N terminal Cytochrom_D1 PF02239.16 OQR96298.1 - 0.02 13.5 0.0 0.13 10.8 0.1 2.2 1 1 1 2 2 2 0 Cytochrome D1 heme domain HPS3_N PF14761.6 OQR96298.1 - 0.059 12.9 0.0 0.44 10.0 0.0 2.4 2 1 0 2 2 2 0 Hermansky-Pudlak syndrome 3 IKI3 PF04762.12 OQR96298.1 - 0.06 11.3 0.0 4 5.3 0.0 2.4 2 0 0 2 2 2 0 IKI3 family Coatomer_WDAD PF04053.14 OQR96298.1 - 0.16 11.0 0.3 1.3 8.0 0.1 2.3 2 0 0 2 2 2 0 Coatomer WD associated region Zn_protease PF05618.11 OQR96299.1 - 0.03 14.2 2.4 0.035 14.0 0.1 2.3 3 0 0 3 3 3 0 Putative ATP-dependant zinc protease MHC_II_beta PF00969.19 OQR96299.1 - 0.22 11.6 1.7 4.1 7.6 0.0 2.9 2 1 0 2 2 2 0 Class II histocompatibility antigen, beta domain Mod_r PF07200.13 OQR96299.1 - 0.26 11.4 30.0 1.7 8.8 13.2 3.5 1 1 1 3 3 3 0 Modifier of rudimentary (Mod(r)) protein Fic PF02661.18 OQR96299.1 - 0.42 11.5 4.6 0.21 12.5 0.4 2.5 2 1 0 2 2 2 0 Fic/DOC family DUF3584 PF12128.8 OQR96299.1 - 1 6.8 37.6 2.8 5.3 34.9 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) Retrotrans_gag PF03732.17 OQR96299.1 - 1.1 9.6 8.7 0.9 9.9 4.9 2.8 2 1 1 3 3 3 0 Retrotransposon gag protein WDCP PF15390.6 OQR96299.1 - 2.4 6.4 11.6 3.5 5.9 11.6 1.3 1 0 0 1 1 1 0 WD repeat and coiled-coil-containing protein family CENP-F_leu_zip PF10473.9 OQR96299.1 - 7.9 6.5 34.5 0.062 13.3 8.8 3.6 2 1 0 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 SIR2 PF02146.17 OQR96300.1 - 4.9e-53 179.7 1.5 1.1e-52 178.6 0.0 2.2 3 0 0 3 3 3 1 Sir2 family TPP_enzyme_M PF00205.22 OQR96300.1 - 0.0071 16.1 0.0 1.5 8.6 0.0 2.2 2 0 0 2 2 2 2 Thiamine pyrophosphate enzyme, central domain BLOC1S3 PF15753.5 OQR96301.1 - 0.00018 21.7 0.1 0.0053 16.9 0.0 2.2 2 0 0 2 2 2 1 Biogenesis of lysosome-related organelles complex 1 subunit 3 Laminin_II PF06009.12 OQR96301.1 - 0.00022 21.2 2.3 0.0013 18.8 0.5 2.2 2 0 0 2 2 2 1 Laminin Domain II EzrA PF06160.12 OQR96301.1 - 0.029 12.6 4.7 0.21 9.7 0.7 2.1 2 0 0 2 2 2 0 Septation ring formation regulator, EzrA YscO PF07321.12 OQR96301.1 - 0.032 14.2 0.8 0.032 14.2 0.8 2.3 2 0 0 2 2 2 0 Type III secretion protein YscO Phage_P2_GpE PF06528.12 OQR96301.1 - 0.052 13.1 0.3 0.22 11.1 0.3 2.1 1 0 0 1 1 1 0 Phage P2 GpE TolA_bind_tri PF16331.5 OQR96301.1 - 0.18 11.9 7.1 0.42 10.7 0.8 3.1 2 0 0 2 2 2 0 TolA binding protein trimerisation PhoU PF01895.19 OQR96301.1 - 0.27 11.7 1.6 1.2 9.7 0.1 2.6 3 0 0 3 3 3 0 PhoU domain COG2 PF06148.11 OQR96301.1 - 0.35 10.9 3.3 0.59 10.2 0.9 2.3 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF1796 PF08795.10 OQR96301.1 - 0.97 9.4 4.8 0.57 10.1 0.5 2.3 1 1 1 2 2 2 0 Putative papain-like cysteine peptidase (DUF1796) DUF745 PF05335.13 OQR96301.1 - 0.98 9.1 8.4 1.9 8.2 2.4 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF745) Got1 PF04178.12 OQR96302.1 - 5.6e-20 71.9 16.7 8.6e-20 71.3 16.7 1.3 1 0 0 1 1 1 1 Got1/Sft2-like family DOT1 PF08123.13 OQR96303.1 - 9.9e-14 51.3 0.0 1.9e-13 50.4 0.0 1.4 1 0 0 1 1 1 1 Histone methylation protein DOT1 Myb_DNA-binding PF00249.31 OQR96303.1 - 4.2e-13 49.3 5.3 4.4e-12 46.0 0.0 3.6 4 0 0 4 4 4 1 Myb-like DNA-binding domain Methyltransf_31 PF13847.6 OQR96303.1 - 9.1e-08 32.0 2.3 3.2e-07 30.2 0.5 2.8 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 OQR96303.1 - 5.2e-06 27.1 0.0 1.4e-05 25.7 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Myb_DNA-bind_7 PF15963.5 OQR96303.1 - 5.6e-05 23.0 0.1 5.6e-05 23.0 0.1 2.7 3 0 0 3 3 3 1 Myb DNA-binding like Methyltransf_11 PF08241.12 OQR96303.1 - 6.4e-05 23.5 0.0 0.00018 22.1 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Myb_DNA-bind_6 PF13921.6 OQR96303.1 - 0.0087 16.3 4.2 0.011 15.9 0.0 3.2 3 1 1 4 4 4 1 Myb-like DNA-binding domain Methyltransf_4 PF02390.17 OQR96303.1 - 0.012 15.1 0.1 1.2 8.6 0.0 2.6 2 0 0 2 2 2 0 Putative methyltransferase Methyltransf_12 PF08242.12 OQR96303.1 - 0.04 14.7 0.0 0.12 13.2 0.0 1.9 1 0 0 1 1 1 0 Methyltransferase domain PrmA PF06325.13 OQR96303.1 - 0.059 12.7 0.0 0.12 11.7 0.0 1.5 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_23 PF13489.6 OQR96303.1 - 0.071 12.9 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain dsDNA_bind PF01984.20 OQR96304.1 - 8.7e-25 87.2 12.0 9.7e-25 87.0 12.0 1.0 1 0 0 1 1 1 1 Double-stranded DNA-binding domain HTH_Tnp_Mu_1 PF02316.16 OQR96304.1 - 0.12 12.5 1.8 0.14 12.3 1.8 1.1 1 0 0 1 1 1 0 Mu DNA-binding domain PAC4 PF16093.5 OQR96305.1 - 3.5e-16 59.1 0.0 4.6e-16 58.8 0.0 1.2 1 0 0 1 1 1 1 Proteasome assembly chaperone 4 Ephrin_rec_like PF07699.13 OQR96326.1 - 1.8e-40 136.4 179.9 5.1e-08 32.6 4.6 16.8 6 3 13 19 19 19 15 Putative ephrin-receptor like Kelch_3 PF13415.6 OQR96326.1 - 5.1e-15 55.3 13.2 6.7e-05 23.1 0.1 6.2 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_4 PF13418.6 OQR96326.1 - 1.3e-09 37.9 15.3 0.016 15.2 1.0 6.6 6 0 0 6 6 6 4 Galactose oxidase, central domain NCD3G PF07562.14 OQR96326.1 - 2.4e-09 37.0 137.9 0.03 14.3 3.2 16.6 6 4 10 19 19 19 15 Nine Cysteines Domain of family 3 GPCR Kelch_2 PF07646.15 OQR96326.1 - 2.5e-06 27.2 0.3 0.32 11.1 0.0 4.8 4 0 0 4 4 4 2 Kelch motif Kelch_6 PF13964.6 OQR96326.1 - 4.1e-06 26.9 10.0 0.11 12.9 0.0 6.1 5 0 0 5 5 5 2 Kelch motif Kelch_5 PF13854.6 OQR96326.1 - 2.2e-05 24.3 6.5 0.16 12.0 0.1 6.1 6 0 0 6 6 6 1 Kelch motif TNFR_c6 PF00020.18 OQR96326.1 - 0.53 10.7 134.3 0.18 12.2 2.9 19.2 6 3 16 23 23 23 0 TNFR/NGFR cysteine-rich region SWM_repeat PF13753.6 OQR96326.1 - 0.9 9.7 3.2 34 4.7 0.0 3.2 3 0 0 3 3 3 0 Putative flagellar system-associated repeat p25-alpha PF05517.12 OQR96327.1 - 6e-25 88.2 0.0 3.6e-14 53.2 0.0 2.4 2 0 0 2 2 2 2 p25-alpha Syntaxin_2 PF14523.6 OQR96327.1 - 0.0051 17.2 3.8 0.0051 17.2 3.8 3.6 3 1 0 3 3 3 1 Syntaxin-like protein RecC_C PF17946.1 OQR96327.1 - 0.13 12.0 1.7 0.17 11.6 0.3 1.8 2 0 0 2 2 2 0 RecC C-terminal domain SKA1 PF07160.12 OQR96327.1 - 0.16 11.8 13.5 1.1 9.0 0.1 3.7 3 0 0 3 3 3 0 Spindle and kinetochore-associated protein 1 DUF948 PF06103.11 OQR96327.1 - 0.85 9.9 6.8 11 6.4 0.0 4.0 3 1 0 3 3 3 0 Bacterial protein of unknown function (DUF948) Syntaxin PF00804.25 OQR96327.1 - 2.5 7.7 16.3 67 3.1 13.4 3.9 2 1 0 2 2 2 0 Syntaxin NOA36 PF06524.12 OQR96328.1 - 0.045 13.1 0.0 0.053 12.8 0.0 1.1 1 0 0 1 1 1 0 NOA36 protein GldH_lipo PF14109.6 OQR96331.1 - 0.15 12.9 0.0 0.2 12.4 0.0 1.1 1 0 0 1 1 1 0 GldH lipoprotein Mito_carr PF00153.27 OQR96332.1 - 3.7e-65 215.9 1.6 1.2e-24 86.0 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 OQR96332.1 - 0.013 14.7 1.1 4 6.5 0.0 2.6 3 0 0 3 3 3 0 Gammaproteobacterial serine protease HA2 PF04408.23 OQR96333.1 - 3.9e-24 85.0 0.0 8.2e-24 84.0 0.0 1.6 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.31 OQR96333.1 - 4.3e-11 43.1 0.0 1e-10 41.9 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 OQR96333.1 - 2.4e-07 30.7 0.1 5.5e-07 29.5 0.1 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 OQR96333.1 - 3.7e-05 24.0 0.2 0.00012 22.4 0.2 1.8 1 1 0 1 1 1 1 AAA domain T2SSE PF00437.20 OQR96333.1 - 0.00061 18.9 0.0 0.0043 16.2 0.0 2.2 2 0 0 2 2 2 1 Type II/IV secretion system protein Flavi_DEAD PF07652.14 OQR96333.1 - 0.012 15.6 0.0 0.021 14.8 0.0 1.4 1 0 0 1 1 1 0 Flavivirus DEAD domain ABC_tran PF00005.27 OQR96333.1 - 0.012 16.1 0.3 1 9.9 0.3 3.1 2 1 0 2 2 2 0 ABC transporter Microtub_bd PF16796.5 OQR96333.1 - 0.02 14.8 0.0 3.8 7.4 0.0 2.6 2 0 0 2 2 2 0 Microtubule binding PhoH PF02562.16 OQR96333.1 - 0.021 14.2 0.1 0.05 13.0 0.1 1.6 1 0 0 1 1 1 0 PhoH-like protein Helicase_RecD PF05127.14 OQR96333.1 - 0.037 13.9 0.0 0.062 13.1 0.0 1.4 1 0 0 1 1 1 0 Helicase SIP1 PF04938.12 OQR96344.1 - 3.2e-37 128.4 0.1 4e-37 128.1 0.1 1.0 1 0 0 1 1 1 1 Survival motor neuron (SMN) interacting protein 1 (SIP1) HGTP_anticodon2 PF12745.7 OQR96344.1 - 0.053 13.0 0.0 0.076 12.5 0.0 1.1 1 0 0 1 1 1 0 Anticodon binding domain of tRNAs NADH_Oxid_Nqo15 PF11497.8 OQR96344.1 - 0.079 13.0 0.0 0.14 12.2 0.0 1.3 1 0 0 1 1 1 0 NADH-quinone oxidoreductase chain 15 IDO PF01231.18 OQR96344.1 - 0.16 10.7 0.0 0.25 10.1 0.0 1.4 1 0 0 1 1 1 0 Indoleamine 2,3-dioxygenase TMEM131_like PF12371.8 OQR96345.1 - 2.5e-08 34.1 2.6 6e-06 26.4 0.0 5.1 5 1 0 5 5 5 1 Transmembrane protein 131-like ASH PF15780.5 OQR96345.1 - 0.0001 22.4 2.4 11 6.3 0.0 6.0 7 0 0 7 7 7 2 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin FAM199X PF15814.5 OQR96346.1 - 0.022 13.8 0.0 0.028 13.5 0.0 1.1 1 0 0 1 1 1 0 Protein family FAM199X E1-E2_ATPase PF00122.20 OQR96347.1 - 1.6e-30 106.0 4.5 2.7e-30 105.2 4.5 1.3 1 0 0 1 1 1 1 E1-E2 ATPase P5-ATPase PF12409.8 OQR96347.1 - 2.6e-05 24.3 7.2 0.00017 21.7 7.2 2.2 1 1 0 1 1 1 1 P5-type ATPase cation transporter Cation_ATPase_N PF00690.26 OQR96347.1 - 2.6e-05 23.8 0.0 5.6e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus TgMIC1 PF11476.8 OQR96347.1 - 0.0045 16.7 0.1 0.9 9.3 0.1 2.4 1 1 1 2 2 2 2 Toxoplasma gondii micronemal protein 1 TgMIC1 Cas_Csm6 PF09659.10 OQR96348.1 - 0.016 14.0 0.3 0.021 13.6 0.3 1.1 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Csm6) Serglycin PF04360.12 OQR96348.1 - 3.5 7.6 8.5 2.1 8.3 6.6 1.6 1 1 1 2 2 2 0 Serglycin Kazal_2 PF07648.15 OQR96349.1 - 0.12 12.5 18.0 0.78 9.9 0.0 3.7 3 1 0 3 3 3 0 Kazal-type serine protease inhibitor domain DUF4077 PF13295.6 OQR96350.1 - 0.066 13.1 3.3 0.089 12.7 3.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4077) DUF2149 PF09919.9 OQR96350.1 - 0.092 13.0 1.1 0.29 11.4 0.5 1.8 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2149) DDDD PF10161.9 OQR96350.1 - 0.48 10.2 1.6 0.46 10.3 0.2 1.7 2 0 0 2 2 2 0 Putative mitochondrial precursor protein Glyco_hydro_38N PF01074.22 OQR96352.1 - 6.8e-84 281.6 8.2 9.5e-84 281.2 8.2 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.13 OQR96352.1 - 6.8e-36 124.4 0.0 1.1e-35 123.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.11 OQR96352.1 - 5.5e-20 71.3 0.3 1.5e-19 70.0 0.3 1.8 1 0 0 1 1 1 1 Alpha mannosidase middle domain APOBEC_N PF08210.11 OQR96352.1 - 0.024 14.6 0.0 22 4.9 0.0 3.3 3 0 0 3 3 3 0 APOBEC-like N-terminal domain Glyco_hydro38C2 PF17677.1 OQR96352.1 - 0.094 12.8 0.0 0.29 11.3 0.0 1.8 1 0 0 1 1 1 0 Glycosyl hydrolases family 38 C-terminal beta sandwich domain PGK PF00162.19 OQR96352.1 - 0.095 11.6 0.8 1.1 8.1 0.1 2.1 2 0 0 2 2 2 0 Phosphoglycerate kinase DUF2367 PF10164.9 OQR96377.1 - 3.9e-14 53.0 14.4 4e-14 53.0 12.8 1.8 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2367) DZR PF12773.7 OQR96377.1 - 0.0024 17.9 9.9 0.042 13.9 9.9 2.4 1 1 0 1 1 1 1 Double zinc ribbon zinc_ribbon_2 PF13240.6 OQR96377.1 - 0.0032 17.1 12.4 0.012 15.4 3.9 3.3 3 1 0 3 3 3 2 zinc-ribbon domain zf-NADH-PPase PF09297.11 OQR96377.1 - 0.14 11.9 0.5 0.14 11.9 0.5 3.2 4 0 0 4 4 4 0 NADH pyrophosphatase zinc ribbon domain zf-ribbon_3 PF13248.6 OQR96377.1 - 0.15 11.5 9.9 2.5 7.6 0.1 3.7 4 0 0 4 4 4 0 zinc-ribbon domain Fer4_2 PF12797.7 OQR96377.1 - 1 9.6 6.9 14 6.1 0.2 3.3 3 0 0 3 3 3 0 4Fe-4S binding domain zf-RanBP PF00641.18 OQR96377.1 - 2 7.8 10.4 10 5.5 5.8 2.4 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others RNB PF00773.19 OQR96378.1 - 1.5e-93 313.7 1.6 1.8e-93 313.5 0.0 1.8 2 1 0 2 2 2 1 RNB domain OB_Dis3 PF17849.1 OQR96378.1 - 9.2e-23 80.1 0.0 2e-22 79.0 0.0 1.6 1 0 0 1 1 1 1 Dis3-like cold-shock domain 2 (CSD2) Rrp44_S1 PF17215.3 OQR96378.1 - 1.1e-15 57.4 0.1 2.1e-15 56.4 0.1 1.5 1 0 0 1 1 1 1 S1 domain Rrp44_CSD1 PF17216.3 OQR96378.1 - 8.5e-13 48.3 0.0 2e-12 47.0 0.0 1.5 1 0 0 1 1 1 1 Rrp44-like cold shock domain CSD2 PF17876.1 OQR96378.1 - 4.9e-08 33.0 0.0 3.2e-06 27.2 0.0 2.8 2 0 0 2 2 2 1 Cold shock domain RGM_C PF06534.13 OQR96379.1 - 0.049 13.1 0.2 0.11 12.0 0.2 1.5 1 0 0 1 1 1 0 Repulsive guidance molecule (RGM) C-terminus CorA PF01544.18 OQR96382.1 - 0.0033 16.8 16.6 0.016 14.6 16.5 1.8 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein SCHIP-1 PF10148.9 OQR96382.1 - 0.024 14.3 0.4 0.074 12.7 0.3 1.8 2 0 0 2 2 2 0 Schwannomin-interacting protein 1 DUF1097 PF06496.11 OQR96382.1 - 0.085 13.0 3.3 0.14 12.3 3.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1097) TerB_C PF15615.6 OQR96382.1 - 0.13 12.6 0.1 0.25 11.7 0.1 1.5 1 0 0 1 1 1 0 TerB-C domain GST_C_5 PF16865.5 OQR96383.1 - 3.9e-11 43.5 0.1 1.2e-10 41.9 0.0 1.8 1 1 1 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 OQR96383.1 - 1.7e-10 41.1 0.0 7.5e-10 39.0 0.0 2.1 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 OQR96383.1 - 7.6e-09 35.9 0.1 2.1e-08 34.5 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 OQR96383.1 - 8.6e-07 29.2 0.0 1.9e-06 28.1 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 OQR96383.1 - 5.8e-05 23.0 0.1 9.4e-05 22.4 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 OQR96383.1 - 0.00039 20.6 0.1 0.00074 19.7 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Glutaredoxin PF00462.24 OQR96383.1 - 0.016 15.4 0.0 0.037 14.2 0.0 1.6 1 0 0 1 1 1 0 Glutaredoxin GST_C PF00043.25 OQR96383.1 - 0.069 13.4 0.0 0.12 12.6 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Hen1_L PF12623.7 OQR96384.1 - 0.082 11.9 0.0 3 6.8 0.0 2.5 2 0 0 2 2 2 0 RNA repair, ligase-Pnkp-associating, region of Hen1 UPF0020 PF01170.18 OQR96385.1 - 1.3e-24 87.0 1.4 5.6e-23 81.6 1.4 2.3 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_25 PF13649.6 OQR96385.1 - 3.1e-06 27.8 0.0 9.8e-06 26.2 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain AviRa PF11599.8 OQR96385.1 - 0.00017 21.1 0.2 0.00048 19.7 0.0 1.7 1 1 1 2 2 2 1 RRNA methyltransferase AviRa Methyltransf_11 PF08241.12 OQR96385.1 - 0.036 14.7 0.0 0.1 13.3 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain Kinesin PF00225.23 OQR96386.1 - 7.9e-90 301.1 0.0 2.4e-89 299.5 0.0 1.9 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 OQR96386.1 - 6.9e-31 107.2 0.1 3.5e-28 98.4 0.0 3.7 3 1 0 3 3 3 1 Microtubule binding Fez1 PF06818.15 OQR96386.1 - 0.58 10.6 85.2 0.41 11.1 13.4 6.3 2 2 5 7 7 7 0 Fez1 CwsA PF10814.8 OQR96386.1 - 1.3 9.2 11.8 2.6 8.2 4.1 3.5 2 0 0 2 2 2 0 Cell wall synthesis protein CwsA MscS_porin PF12795.7 OQR96386.1 - 5 6.6 84.6 1.7 8.1 23.0 3.5 3 0 0 3 3 3 0 Mechanosensitive ion channel porin domain Dynamin_M PF01031.20 OQR96387.1 - 4e-105 351.1 0.0 1.4e-104 349.4 0.0 1.8 2 0 0 2 2 2 1 Dynamin central region Dynamin_N PF00350.23 OQR96387.1 - 4.7e-59 199.2 0.3 9.5e-59 198.2 0.0 1.7 2 0 0 2 2 2 1 Dynamin family GED PF02212.18 OQR96387.1 - 1.3e-27 95.8 1.5 3.4e-27 94.4 1.5 1.8 1 0 0 1 1 1 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 OQR96387.1 - 8.9e-05 22.5 0.1 0.00032 20.8 0.1 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 OQR96387.1 - 0.026 14.9 0.1 0.55 10.6 0.0 2.7 3 0 0 3 3 3 0 AAA ATPase domain Ribosomal_L7Ae PF01248.26 OQR96388.1 - 5.8e-27 93.3 0.9 7.4e-27 92.9 0.9 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family DUF4527 PF15030.6 OQR96388.1 - 0.061 12.7 1.3 0.076 12.4 1.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4527) PELOTA_1 PF15608.6 OQR96388.1 - 0.11 12.4 0.0 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 PELOTA RNA binding domain Pkinase PF00069.25 OQR96389.1 - 2.8e-60 203.9 0.0 3.4e-60 203.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQR96389.1 - 3e-26 92.2 0.1 4.6e-26 91.6 0.1 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 OQR96389.1 - 0.00071 19.6 0.0 0.0039 17.1 0.0 2.0 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 OQR96389.1 - 0.003 16.9 0.0 0.01 15.2 0.0 1.8 2 0 0 2 2 2 1 Kinase-like Choline_kinase PF01633.20 OQR96389.1 - 0.0052 16.4 0.1 0.01 15.4 0.1 1.5 1 1 0 1 1 1 1 Choline/ethanolamine kinase YrbL-PhoP_reg PF10707.9 OQR96389.1 - 0.026 14.0 0.3 0.072 12.6 0.0 1.8 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL ABC1 PF03109.16 OQR96389.1 - 0.028 14.6 0.1 0.055 13.6 0.1 1.5 1 0 0 1 1 1 0 ABC1 family Kdo PF06293.14 OQR96389.1 - 0.049 13.0 0.1 0.091 12.1 0.1 1.5 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family OTCace_N PF02729.21 OQR96390.1 - 1.5e-47 161.3 0.0 3.7e-47 160.1 0.0 1.7 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain OTCace PF00185.24 OQR96390.1 - 6.5e-34 117.3 0.1 1.1e-33 116.5 0.1 1.4 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain XPC-binding PF09280.11 OQR96391.1 - 0.16 11.7 0.2 0.16 11.7 0.2 2.5 3 0 0 3 3 3 0 XPC-binding domain Pkinase PF00069.25 OQR96392.1 - 2.5e-63 213.9 0.0 3.7e-63 213.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQR96392.1 - 1.3e-46 159.0 0.0 1.8e-46 158.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OQR96392.1 - 2.6e-05 23.2 0.0 4.9e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 OQR96392.1 - 0.0016 17.8 0.0 0.004 16.5 0.0 1.6 2 0 0 2 2 2 1 Kinase-like Myosin_head PF00063.21 OQR96393.1 - 1.2e-134 450.1 0.3 1.4e-134 449.9 0.3 1.0 1 0 0 1 1 1 1 Myosin head (motor domain) AAA_16 PF13191.6 OQR96393.1 - 0.0019 18.6 0.0 0.0044 17.4 0.0 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 OQR96393.1 - 0.028 14.7 0.0 0.11 12.8 0.0 1.9 1 1 1 2 2 2 0 AAA domain AAA_19 PF13245.6 OQR96393.1 - 0.035 14.5 0.0 0.13 12.6 0.0 1.9 2 0 0 2 2 2 0 AAA domain Sigma54_activat PF00158.26 OQR96393.1 - 0.072 12.8 0.0 0.16 11.6 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain TsaE PF02367.17 OQR96393.1 - 0.11 12.5 0.0 0.28 11.2 0.0 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE RsgA_GTPase PF03193.16 OQR96393.1 - 0.11 12.4 0.0 0.21 11.5 0.0 1.3 1 0 0 1 1 1 0 RsgA GTPase T2SSE PF00437.20 OQR96393.1 - 0.11 11.5 0.0 0.19 10.8 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein Telomere_Sde2_2 PF13297.6 OQR96393.1 - 0.51 10.0 2.8 0.37 10.5 0.2 2.1 2 0 0 2 2 2 0 Telomere stability C-terminal HSF_DNA-bind PF00447.17 OQR96426.1 - 2.2e-24 85.9 2.8 5.5e-24 84.6 2.8 1.7 1 0 0 1 1 1 1 HSF-type DNA-binding Ank_2 PF12796.7 OQR96426.1 - 1.1e-19 70.8 0.1 1.6e-08 35.0 0.0 3.5 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQR96426.1 - 2e-19 69.7 1.5 6.3e-08 33.0 0.1 4.5 2 1 3 5 5 5 3 Ankyrin repeats (many copies) Ank PF00023.30 OQR96426.1 - 1.1e-16 60.4 3.3 6.2e-07 29.6 0.0 4.8 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.6 OQR96426.1 - 2.4e-15 56.4 0.9 2.6e-06 27.6 0.2 3.5 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQR96426.1 - 1.3e-14 52.8 2.3 9.9e-05 22.5 0.0 4.7 4 0 0 4 4 4 3 Ankyrin repeat DUF905 PF06006.12 OQR96426.1 - 0.13 12.3 0.0 2 8.5 0.0 2.4 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF905) Aldedh PF00171.22 OQR96427.1 - 2.8e-124 415.1 0.3 3.3e-124 414.9 0.3 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 OQR96427.1 - 0.0086 15.2 0.0 0.013 14.6 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA reductase (LuxC) RNA_pol_Rpb1_5 PF04998.17 OQR96429.1 - 1.7e-91 306.4 0.1 2.9e-91 305.6 0.1 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 OQR96429.1 - 1.6e-63 213.9 0.3 3.3e-63 212.8 0.3 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_1 PF04997.12 OQR96429.1 - 9.6e-32 110.5 0.4 2.8e-29 102.5 0.1 3.2 2 1 0 2 2 2 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_3 PF04983.18 OQR96429.1 - 2.5e-30 105.5 0.0 5.9e-30 104.3 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.17 OQR96429.1 - 5.8e-20 71.2 0.0 1.9e-19 69.6 0.0 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 Ribosomal_S3Ae PF01015.18 OQR96429.1 - 0.15 11.7 0.2 1 8.9 0.0 2.1 2 0 0 2 2 2 0 Ribosomal S3Ae family E1-E2_ATPase PF00122.20 OQR96430.1 - 3e-43 147.4 0.1 3e-43 147.4 0.1 2.4 2 1 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 OQR96430.1 - 6.1e-17 62.6 0.0 1.6e-16 61.3 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 OQR96430.1 - 1.4e-12 47.1 0.0 2.7e-12 46.2 0.0 1.5 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 OQR96430.1 - 0.00023 21.0 0.3 0.0013 18.6 0.1 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 OQR96430.1 - 0.17 12.3 0.0 0.43 11.0 0.0 1.7 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Phage_holin_Dp1 PF16938.5 OQR96430.1 - 0.32 11.2 2.9 22 5.4 0.0 2.7 2 0 0 2 2 2 0 Putative phage holin Dp-1 TRAUB PF08164.12 OQR96431.1 - 2.2e-18 66.5 0.2 2.2e-18 66.5 0.2 2.7 3 0 0 3 3 3 1 Apoptosis-antagonizing transcription factor, C-terminal AATF-Che1 PF13339.6 OQR96431.1 - 3.1e-09 37.6 0.4 3.1e-09 37.6 0.4 3.0 3 1 0 3 3 3 1 Apoptosis antagonizing transcription factor GBP PF02263.19 OQR96431.1 - 0.002 17.4 0.2 0.0042 16.4 0.2 1.4 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain EII-GUT PF03608.13 OQR96431.1 - 0.26 11.2 0.0 0.46 10.4 0.0 1.3 1 0 0 1 1 1 0 PTS system enzyme II sorbitol-specific factor Fucose_iso_N2 PF07882.12 OQR96431.1 - 0.49 9.9 6.4 0.11 12.0 1.1 2.5 2 1 2 4 4 4 0 L-fucose isomerase, second N-terminal domain DUF4337 PF14235.6 OQR96431.1 - 0.69 10.0 3.1 2.2 8.4 3.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) Metallophos PF00149.28 OQR96432.1 - 1.9e-16 61.2 3.8 2.8e-16 60.7 3.8 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 OQR96432.1 - 9e-12 45.5 0.1 1.2e-10 41.8 0.1 2.0 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos_3 PF14582.6 OQR96432.1 - 0.0021 17.4 0.0 0.036 13.4 0.0 2.0 2 0 0 2 2 2 1 Metallophosphoesterase, calcineurin superfamily zf-RING_2 PF13639.6 OQR96433.1 - 4.7e-13 49.2 11.2 5.8e-13 48.9 8.6 2.4 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.7 OQR96433.1 - 6.2e-09 36.0 12.4 1.6e-08 34.7 12.4 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 OQR96433.1 - 1.2e-07 31.5 8.0 1.2e-07 31.5 8.0 2.9 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) PX PF00787.24 OQR96433.1 - 1.4e-07 31.5 0.4 2e-07 31.0 0.4 1.2 1 0 0 1 1 1 1 PX domain zf-RING_11 PF17123.5 OQR96433.1 - 1.8e-07 30.8 4.7 1.8e-07 30.8 4.7 2.9 3 0 0 3 3 3 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 OQR96433.1 - 2.9e-07 30.2 9.0 2.9e-07 30.2 9.0 2.6 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 OQR96433.1 - 1.2e-06 28.2 4.9 2.8e-06 27.1 3.5 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OQR96433.1 - 1.4e-05 25.0 5.8 1.4e-05 25.0 5.8 3.0 3 1 0 3 3 3 1 RING-type zinc-finger zf-RING_5 PF14634.6 OQR96433.1 - 8.8e-05 22.4 8.8 0.00012 22.0 6.9 2.2 2 0 0 2 2 2 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 OQR96433.1 - 0.0005 20.1 6.9 0.0012 18.9 6.6 1.7 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger RINGv PF12906.7 OQR96433.1 - 0.0025 17.9 7.1 0.0077 16.3 7.1 1.8 1 0 0 1 1 1 1 RING-variant domain zinc_ribbon_16 PF17034.5 OQR96433.1 - 0.0054 16.9 5.4 0.0054 16.9 5.4 1.9 2 1 0 2 2 2 1 Zinc-ribbon like family FANCL_C PF11793.8 OQR96433.1 - 0.0063 16.7 6.1 0.025 14.7 6.1 2.1 1 1 0 1 1 1 1 FANCL C-terminal domain Zn_ribbon_17 PF17120.5 OQR96433.1 - 0.026 14.2 7.3 0.026 14.2 7.3 2.1 2 1 0 2 2 2 0 Zinc-ribbon, C4HC2 type zf-RING_4 PF14570.6 OQR96433.1 - 0.067 13.0 5.5 0.2 11.5 5.5 1.8 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.6 OQR96433.1 - 0.89 9.8 12.2 0.21 11.8 7.5 2.5 2 1 0 2 2 2 0 zinc finger of C3HC4-type, RING Guanylate_cyc PF00211.20 OQR96434.1 - 6.6e-11 42.2 0.0 1.3e-10 41.2 0.0 1.4 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain LPG_synthase_TM PF03706.13 OQR96434.1 - 0.011 15.3 5.3 0.024 14.2 5.3 1.5 1 0 0 1 1 1 0 Lysylphosphatidylglycerol synthase TM region DUF1129 PF06570.11 OQR96434.1 - 0.063 12.8 2.1 0.11 12.0 2.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) COX14 PF14880.6 OQR96434.1 - 0.1 12.5 1.1 0.27 11.1 0.3 2.2 2 0 0 2 2 2 0 Cytochrome oxidase c assembly Ribosomal_L13e PF01294.18 OQR96435.1 - 6.5e-76 254.2 3.6 8.3e-76 253.8 3.6 1.1 1 0 0 1 1 1 1 Ribosomal protein L13e PLDc PF00614.22 OQR96436.1 - 3.1e-17 61.9 2.3 1.1e-08 34.9 0.2 2.7 2 0 0 2 2 2 2 Phospholipase D Active site motif PLDc_2 PF13091.6 OQR96436.1 - 6.1e-15 55.3 0.1 1.1e-09 38.3 0.0 2.9 2 1 0 2 2 2 2 PLD-like domain EF-hand_7 PF13499.6 OQR96437.1 - 4.6e-06 27.0 0.4 0.00022 21.6 0.1 2.4 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 OQR96437.1 - 1e-05 25.1 0.7 0.094 12.7 0.1 3.0 3 0 0 3 3 3 2 EF-hand domain EF-hand_1 PF00036.32 OQR96437.1 - 1e-05 24.7 0.1 0.018 14.5 0.0 2.8 2 0 0 2 2 2 2 EF hand Glyco_trans_1_3 PF13528.6 OQR96437.1 - 0.064 12.5 0.0 0.097 11.9 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 1 ELFV_dehydrog PF00208.21 OQR96438.1 - 1.9e-56 191.5 0.1 3.1e-56 190.8 0.1 1.3 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Bac_GDH PF05088.12 OQR96438.1 - 2.7e-24 84.9 0.0 5.3e-15 54.1 0.0 2.5 2 0 0 2 2 2 2 Bacterial NAD-glutamate dehydrogenase Sld7_C PF18596.1 OQR96438.1 - 0.051 13.7 0.1 4.8 7.4 0.0 2.8 2 0 0 2 2 2 0 Sld7 C-terminal domain ELFV_dehydrog_N PF02812.18 OQR96438.1 - 0.061 13.2 0.0 0.22 11.4 0.0 1.9 1 0 0 1 1 1 0 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain Ribosomal_L24e PF01246.20 OQR96439.1 - 6.3e-26 90.4 0.3 1.8e-25 88.9 0.3 1.9 1 0 0 1 1 1 1 Ribosomal protein L24e WD40 PF00400.32 OQR96439.1 - 1.7e-14 54.0 8.3 6.1e-05 23.7 1.8 4.9 5 0 0 5 5 5 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OQR96439.1 - 0.00039 20.7 0.5 3 8.2 0.0 3.6 3 1 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 OQR96439.1 - 0.0015 17.6 0.0 0.023 13.7 0.0 2.2 1 1 1 2 2 2 1 WD40 region of Ge1, enhancer of mRNA-decapping protein HAD_SAK_2 PF18143.1 OQR96439.1 - 0.12 12.7 0.4 0.23 11.8 0.4 1.5 1 0 0 1 1 1 0 HAD domain in Swiss Army Knife RNA repair proteins CTP_transf_like PF01467.26 OQR96439.1 - 0.16 12.2 0.5 0.41 10.8 0.5 1.7 1 0 0 1 1 1 0 Cytidylyltransferase-like Ank_2 PF12796.7 OQR96485.1 - 3.4e-54 181.4 17.3 5.7e-15 55.7 0.4 6.8 5 2 1 7 7 7 6 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OQR96485.1 - 6.8e-42 141.0 24.0 9.9e-12 44.9 0.3 10.6 6 3 5 11 11 11 7 Ankyrin repeats (many copies) Ank PF00023.30 OQR96485.1 - 3.1e-38 128.6 21.4 1.3e-06 28.5 0.0 11.7 12 0 0 12 12 12 8 Ankyrin repeat Ank_3 PF13606.6 OQR96485.1 - 4.2e-38 125.0 14.2 0.00088 19.6 0.0 12.8 13 0 0 13 13 13 8 Ankyrin repeat Ank_4 PF13637.6 OQR96485.1 - 4.9e-37 125.8 5.3 2.9e-09 37.3 0.0 9.6 7 1 3 10 10 10 7 Ankyrin repeats (many copies) RPA_interact_C PF14768.6 OQR96485.1 - 0.78 10.4 3.9 2.2 8.9 2.1 2.6 2 0 0 2 2 2 0 Replication protein A interacting C-terminal zf-ribbon_3 PF13248.6 OQR96485.1 - 0.86 9.1 3.1 2.1 7.8 3.1 1.7 1 0 0 1 1 1 0 zinc-ribbon domain HU-CCDC81_bac_2 PF18175.1 OQR96486.1 - 0.13 12.1 0.1 0.4 10.6 0.1 1.8 1 0 0 1 1 1 0 CCDC81-like prokaryotic HU domain 2 SET PF00856.28 OQR96486.1 - 0.15 12.5 0.2 0.32 11.4 0.1 1.6 2 0 0 2 2 2 0 SET domain Hemerythrin PF01814.23 OQR96487.1 - 0.45 11.2 4.4 0.97 10.1 4.4 1.6 1 1 0 1 1 1 0 Hemerythrin HHE cation binding domain BT1 PF03092.16 OQR96488.1 - 1.3e-17 63.3 50.6 1e-05 24.0 0.7 9.4 10 0 0 10 10 10 5 BT1 family PUCC PF03209.15 OQR96488.1 - 0.0017 17.5 2.7 0.013 14.5 0.4 7.6 9 0 0 9 9 9 4 PUCC protein CrgA PF06781.12 OQR96488.1 - 0.0097 15.9 6.0 7.2 6.8 0.4 5.6 3 0 0 3 3 3 2 Cell division protein CrgA PUL PF08324.11 OQR96488.1 - 0.062 12.5 0.3 6.4 5.9 0.0 2.5 2 0 0 2 2 2 0 PUL domain DUF3754 PF12576.8 OQR96488.1 - 0.13 12.2 6.8 12 5.8 0.1 5.1 5 0 0 5 5 5 0 Protein of unknown function (DUF3754) EF1_GNE PF00736.19 OQR96489.1 - 0.3 11.3 3.0 6.1 7.1 0.5 3.7 2 0 0 2 2 2 0 EF-1 guanine nucleotide exchange domain DUF2232 PF09991.9 OQR96489.1 - 1.4 8.0 11.0 1.6 7.8 0.1 3.9 4 0 0 4 4 4 0 Predicted membrane protein (DUF2232) Peptidase_C69 PF03577.15 OQR96490.1 - 1.2e-46 159.4 0.0 3.3e-46 158.0 0.0 1.7 1 1 0 1 1 1 1 Peptidase family C69 Pkinase PF00069.25 OQR96492.1 - 1.7e-74 250.5 0.0 2.4e-74 250.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQR96492.1 - 9.7e-33 113.5 0.0 1.3e-32 113.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 OQR96492.1 - 8.8e-06 25.2 0.3 7.1e-05 22.2 0.2 2.1 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 OQR96492.1 - 0.00063 19.1 0.0 0.00098 18.5 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 OQR96492.1 - 0.00088 18.2 0.0 0.0018 17.2 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Pox_ser-thr_kin PF05445.11 OQR96492.1 - 0.02 13.9 0.7 0.038 13.0 0.1 1.6 1 1 1 2 2 2 0 Poxvirus serine/threonine protein kinase YrbL-PhoP_reg PF10707.9 OQR96492.1 - 0.027 14.0 0.2 0.061 12.8 0.1 1.6 1 1 0 1 1 1 0 PhoP regulatory network protein YrbL RIO1 PF01163.22 OQR96492.1 - 0.042 13.4 0.6 0.11 12.0 0.6 1.6 1 1 0 1 1 1 0 RIO1 family DUF4265 PF14085.6 OQR96492.1 - 0.059 13.3 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4265) Colicin_Pyocin PF01320.18 OQR96492.1 - 0.15 12.2 0.7 1.1 9.4 0.7 2.2 1 1 0 1 1 1 0 Colicin immunity protein / pyocin immunity protein DUF4260 PF14079.6 OQR96493.1 - 0.053 13.5 1.1 0.078 12.9 1.0 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4260) PX PF00787.24 OQR96494.1 - 1.9e-06 27.8 0.0 8e-06 25.8 0.0 2.1 1 0 0 1 1 1 1 PX domain PDZ_6 PF17820.1 OQR96494.1 - 0.0042 16.9 0.0 2.4 8.1 0.0 3.6 3 0 0 3 3 3 1 PDZ domain APG6_N PF17675.1 OQR96494.1 - 0.014 15.9 2.0 0.014 15.9 2.0 3.6 1 1 1 2 2 2 0 Apg6 coiled-coil region YejG PF13989.6 OQR96494.1 - 0.022 15.2 1.3 0.13 12.7 0.2 2.8 4 0 0 4 4 4 0 YejG-like protein Cmyb_C PF09316.10 OQR96494.1 - 0.051 13.3 0.2 0.15 11.8 0.2 1.7 1 0 0 1 1 1 0 C-myb, C-terminal Ago_N_1 PF18351.1 OQR96494.1 - 0.068 13.6 0.3 1.3 9.5 0.1 2.9 2 1 1 3 3 3 0 Fungal Argonaute N-terminal domain DAO PF01266.24 OQR96494.1 - 0.12 11.9 0.1 1.3 8.6 0.0 2.3 1 1 0 2 2 2 0 FAD dependent oxidoreductase PP2C_2 PF13672.6 OQR96494.1 - 3.9 7.0 6.5 4 7.0 3.9 2.2 2 0 0 2 2 2 0 Protein phosphatase 2C Carn_acyltransf PF00755.20 OQR96495.1 - 2.1e-180 601.2 0.0 2.4e-180 601.1 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase BetaGal_dom4_5 PF13364.6 OQR96495.1 - 0.045 14.3 0.0 0.1 13.2 0.0 1.5 1 0 0 1 1 1 0 Beta-galactosidase jelly roll domain Pkinase PF00069.25 OQR96496.1 - 3e-44 151.4 0.0 3.9e-30 105.1 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OQR96496.1 - 7.2e-26 91.0 0.0 5e-11 42.4 0.0 3.0 3 0 0 3 3 3 3 Protein tyrosine kinase Kinase-like PF14531.6 OQR96496.1 - 0.00075 18.9 0.1 0.0028 17.0 0.0 1.8 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 OQR96496.1 - 0.00091 18.6 0.0 0.0018 17.7 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 OQR96496.1 - 0.0017 18.0 0.0 2 8.0 0.0 2.2 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Pkinase_fungal PF17667.1 OQR96496.1 - 0.019 13.8 0.0 0.031 13.1 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase APH PF01636.23 OQR96496.1 - 0.17 11.8 0.1 0.47 10.3 0.0 1.7 2 1 1 3 3 3 0 Phosphotransferase enzyme family TPK_catalytic PF04263.16 OQR96497.1 - 3.4e-27 94.9 0.0 4.7e-27 94.4 0.0 1.1 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, catalytic domain TPK_B1_binding PF04265.14 OQR96497.1 - 1.8e-18 66.0 0.1 2.6e-18 65.5 0.1 1.2 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, vitamin B1 binding domain HAT PF02184.16 OQR96498.1 - 1.1e-28 98.9 58.2 2.3e-07 30.6 0.2 15.0 15 1 0 15 15 14 9 HAT (Half-A-TPR) repeat TPR_14 PF13428.6 OQR96498.1 - 1.6e-18 65.8 28.2 0.0079 16.9 0.6 12.2 5 5 8 13 13 13 6 Tetratricopeptide repeat Suf PF05843.14 OQR96498.1 - 8.4e-17 62.1 22.2 0.00066 19.8 0.0 6.4 2 2 4 6 6 6 5 Suppressor of forked protein (Suf) TPR_19 PF14559.6 OQR96498.1 - 3.5e-14 53.1 1.7 0.032 14.7 0.0 6.8 5 3 2 7 7 7 3 Tetratricopeptide repeat TPR_17 PF13431.6 OQR96498.1 - 2.2e-08 33.9 3.1 0.82 10.2 0.1 7.2 8 0 0 8 8 6 1 Tetratricopeptide repeat TPR_16 PF13432.6 OQR96498.1 - 9.9e-08 32.5 11.0 0.014 16.0 0.0 7.2 6 2 1 7 7 7 2 Tetratricopeptide repeat TPR_2 PF07719.17 OQR96498.1 - 4.6e-07 29.5 17.1 2.2 8.6 0.5 9.5 11 0 0 11 11 11 2 Tetratricopeptide repeat Mad3_BUB1_I PF08311.12 OQR96498.1 - 1.4e-05 25.1 37.0 0.075 13.0 1.3 7.9 5 2 1 7 7 7 4 Mad3/BUB1 homology region 1 TPR_12 PF13424.6 OQR96498.1 - 0.0015 18.8 17.5 1.6 9.1 0.1 8.2 8 2 1 9 9 8 1 Tetratricopeptide repeat TPR_8 PF13181.6 OQR96498.1 - 0.0047 17.0 14.2 1.2 9.5 0.1 7.5 9 0 0 9 9 8 1 Tetratricopeptide repeat U3_assoc_6 PF08640.11 OQR96498.1 - 0.0072 16.4 20.2 0.22 11.6 0.5 6.4 4 3 2 6 6 6 2 U3 small nucleolar RNA-associated protein 6 TPR_9 PF13371.6 OQR96498.1 - 0.014 15.5 7.3 0.046 13.9 0.1 4.2 3 1 1 4 4 4 0 Tetratricopeptide repeat BSD PF03909.17 OQR96498.1 - 0.086 12.9 3.0 0.35 10.9 0.4 2.9 2 0 0 2 2 2 0 BSD domain TPR_6 PF13174.6 OQR96498.1 - 0.24 12.1 18.9 40 5.2 0.0 8.9 10 1 1 11 11 9 0 Tetratricopeptide repeat TPR_7 PF13176.6 OQR96498.1 - 0.69 10.1 14.9 14 6.0 0.1 6.9 8 0 0 8 8 8 0 Tetratricopeptide repeat TPR_1 PF00515.28 OQR96498.1 - 1.3 9.0 4.9 26 4.9 0.0 4.2 4 0 0 4 4 3 0 Tetratricopeptide repeat ABC_tran PF00005.27 OQR96518.1 - 5.3e-38 130.6 0.0 1.4e-25 90.4 0.0 2.3 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 OQR96518.1 - 8.8e-07 28.6 0.4 0.019 14.4 0.0 3.1 3 0 0 3 3 3 2 RecF/RecN/SMC N terminal domain DEAD PF00270.29 OQR96518.1 - 4.5e-05 23.3 0.0 0.34 10.6 0.0 2.8 2 2 0 2 2 2 2 DEAD/DEAH box helicase AAA_22 PF13401.6 OQR96518.1 - 6.3e-05 23.3 0.8 0.017 15.4 0.2 3.0 2 2 0 2 2 2 1 AAA domain SbcCD_C PF13558.6 OQR96518.1 - 0.00026 21.2 1.3 1.3 9.3 0.0 3.8 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit ABC_ATPase PF09818.9 OQR96518.1 - 0.00029 19.8 0.7 0.011 14.5 0.0 2.6 3 0 0 3 3 3 1 Predicted ATPase of the ABC class AAA_29 PF13555.6 OQR96518.1 - 0.0022 17.7 0.1 0.0049 16.6 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.6 OQR96518.1 - 0.0029 18.0 0.1 0.018 15.4 0.1 2.1 2 1 0 2 2 2 1 AAA ATPase domain TniB PF05621.11 OQR96518.1 - 0.0037 16.7 0.3 4.9 6.5 0.0 3.3 3 1 0 3 3 3 1 Bacterial TniB protein AAA_30 PF13604.6 OQR96518.1 - 0.0046 16.7 0.6 0.019 14.7 0.1 2.2 2 2 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 OQR96518.1 - 0.012 15.6 0.0 0.021 14.7 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase Zeta_toxin PF06414.12 OQR96518.1 - 0.013 14.8 0.0 0.024 13.9 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_21 PF13304.6 OQR96518.1 - 0.016 15.1 0.9 0.56 10.0 0.1 2.8 3 0 0 3 3 3 0 AAA domain, putative AbiEii toxin, Type IV TA system G-alpha PF00503.20 OQR96518.1 - 0.031 13.4 0.0 0.051 12.7 0.0 1.3 1 0 0 1 1 1 0 G-protein alpha subunit AAA_5 PF07728.14 OQR96518.1 - 0.062 13.3 0.1 3.5 7.6 0.0 3.1 3 1 0 3 3 3 0 AAA domain (dynein-related subfamily) MMR_HSR1 PF01926.23 OQR96518.1 - 0.092 12.8 0.3 0.28 11.3 0.3 1.9 1 1 0 1 1 1 0 50S ribosome-binding GTPase Pet191_N PF10203.9 OQR96518.1 - 0.098 13.0 0.2 0.21 11.9 0.2 1.4 1 0 0 1 1 1 0 Cytochrome c oxidase assembly protein PET191 AAA_15 PF13175.6 OQR96518.1 - 0.11 12.2 0.0 0.17 11.6 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain AAA_25 PF13481.6 OQR96518.1 - 0.16 11.5 1.0 1.3 8.5 0.4 2.6 2 1 0 2 2 2 0 AAA domain AAA_24 PF13479.6 OQR96518.1 - 0.16 11.7 0.0 0.83 9.3 0.0 2.2 2 1 0 2 2 2 0 AAA domain Acetyltransf_3 PF13302.7 OQR96519.1 - 1.1e-11 45.5 0.1 1.6e-11 45.1 0.1 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 OQR96519.1 - 0.0053 17.0 0.0 0.0076 16.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family QLQ PF08880.11 OQR96519.1 - 0.18 11.6 0.1 15 5.4 1.6 2.7 3 0 0 3 3 3 0 QLQ PGK PF00162.19 OQR96525.1 - 2e-21 76.4 0.1 3.3e-13 49.3 0.0 3.3 3 0 0 3 3 3 3 Phosphoglycerate kinase CENP-B_dimeris PF09026.10 OQR96525.1 - 0.0062 16.9 17.2 0.18 12.2 1.4 2.5 2 0 0 2 2 2 2 Centromere protein B dimerisation domain GCIP PF13324.6 OQR96525.1 - 0.62 9.6 7.4 0.56 9.8 1.0 2.5 2 0 0 2 2 2 0 Grap2 and cyclin-D-interacting FAM176 PF14851.6 OQR96525.1 - 2.2 7.9 16.3 2.5 7.7 1.0 3.2 3 0 0 3 3 3 0 FAM176 family PAC1 PF16094.5 OQR96525.1 - 8.1 5.5 8.7 18 4.4 3.5 2.5 2 0 0 2 2 2 0 Proteasome assembly chaperone 4 ORC_WH_C PF18137.1 OQR96525.1 - 9.3 6.3 11.9 1.1 9.3 0.7 3.1 3 0 0 3 3 3 0 Origin recognition complex winged helix C-terminal Ysc84 PF04366.12 OQR96526.1 - 7.4e-32 109.8 0.2 1.5e-31 108.8 0.2 1.5 1 0 0 1 1 1 1 Las17-binding protein actin regulator FYVE PF01363.21 OQR96526.1 - 2.7e-13 49.9 6.0 2.7e-13 49.9 6.0 3.4 3 1 0 3 3 3 1 FYVE zinc finger DZR PF12773.7 OQR96526.1 - 0.0027 17.7 1.3 0.0027 17.7 1.3 4.3 3 1 1 4 4 4 1 Double zinc ribbon EMC3_TMCO1 PF01956.16 OQR96526.1 - 0.014 15.1 1.1 0.073 12.8 1.1 2.0 1 1 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like FYVE_2 PF02318.16 OQR96526.1 - 0.02 15.1 7.8 0.02 15.1 7.8 2.3 2 1 0 2 2 2 0 FYVE-type zinc finger CRT10 PF08728.10 OQR96526.1 - 0.064 11.4 7.8 0.079 11.1 7.8 1.1 1 0 0 1 1 1 0 CRT10 Exonuc_VII_L PF02601.15 OQR96526.1 - 8.2 5.9 18.5 14 5.2 17.9 1.6 2 0 0 2 2 2 0 Exonuclease VII, large subunit HypA PF01155.19 OQR96526.1 - 9.5 6.3 17.3 0.039 14.0 1.3 3.4 3 0 0 3 3 3 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Vps26 PF03643.15 OQR96527.1 - 1.1e-98 329.6 2.7 1.4e-98 329.3 2.7 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Arrestin_N PF00339.29 OQR96527.1 - 7.7e-05 22.8 3.1 0.1 12.7 0.2 3.5 3 1 1 4 4 4 2 Arrestin (or S-antigen), N-terminal domain Kinesin PF00225.23 OQR96555.1 - 4e-11 42.4 0.1 9.6e-08 31.3 0.0 3.1 2 1 1 3 3 3 2 Kinesin motor domain Microtub_bd PF16796.5 OQR96555.1 - 9.3e-06 25.6 4.3 3e-05 24.0 0.0 3.3 4 0 0 4 4 4 1 Microtubule binding MMR_HSR1 PF01926.23 OQR96555.1 - 0.31 11.1 1.1 5.9 7.0 0.1 3.2 2 1 0 2 2 2 0 50S ribosome-binding GTPase GCK PF07802.11 OQR96555.1 - 6.8 7.2 8.0 0.35 11.3 0.3 2.8 3 0 0 3 3 3 0 GCK domain Sulfate_transp PF00916.20 OQR96556.1 - 3.5e-76 256.4 21.1 3.6e-75 253.1 21.1 2.0 1 1 0 1 1 1 1 Sulfate permease family STAS PF01740.21 OQR96556.1 - 6.4e-14 51.6 0.0 1.5e-13 50.4 0.0 1.6 2 0 0 2 2 2 1 STAS domain BIV_Env PF05858.12 OQR96556.1 - 0.091 10.9 0.1 0.23 9.6 0.0 1.6 2 0 0 2 2 2 0 Bovine immunodeficiency virus surface protein (SU) DUF2755 PF10954.8 OQR96556.1 - 3.6 7.5 8.0 2.3 8.2 0.2 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF2755) Saf_2TM PF18303.1 OQR96556.1 - 6.4 6.3 6.9 1.6 8.3 0.5 3.0 3 0 0 3 3 3 0 SAVED-fused 2TM effector domain RRM_1 PF00076.22 OQR96557.1 - 3.7e-10 39.5 0.0 6.8e-10 38.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ion_trans PF00520.31 OQR96558.1 - 1.3e-26 93.3 33.2 2.3e-14 53.3 11.4 3.0 3 0 0 3 3 3 2 Ion transport protein Ion_trans_2 PF07885.16 OQR96558.1 - 3.3e-16 59.0 19.6 4.6e-09 36.1 0.6 3.2 3 0 0 3 3 3 2 Ion channel IRK PF01007.20 OQR96558.1 - 0.002 17.9 1.6 1 9.2 0.1 3.6 2 1 0 2 2 2 2 Inward rectifier potassium channel transmembrane domain MRP-L20 PF12824.7 OQR96558.1 - 0.022 14.9 0.7 0.044 14.0 0.1 1.8 2 0 0 2 2 2 0 Mitochondrial ribosomal protein subunit L20 SWIRM PF04433.17 OQR96558.1 - 0.11 12.9 0.7 0.61 10.5 0.2 2.5 2 0 0 2 2 2 0 SWIRM domain Peptidase_M48_N PF16491.5 OQR96559.1 - 5.3e-50 169.8 9.6 5.3e-50 169.8 9.6 3.0 3 1 1 4 4 4 1 CAAX prenyl protease N-terminal, five membrane helices Peptidase_M48 PF01435.18 OQR96559.1 - 1.7e-44 152.0 0.0 3.2e-44 151.1 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M48 Ion_trans PF00520.31 OQR96559.1 - 2.5e-34 118.6 33.9 8.7e-21 74.3 4.6 3.6 4 0 0 4 4 4 2 Ion transport protein Ion_trans_2 PF07885.16 OQR96559.1 - 9.9e-15 54.3 21.2 2.3e-09 37.1 1.2 3.9 4 0 0 4 4 4 2 Ion channel Peptidase_M56 PF05569.11 OQR96559.1 - 0.091 11.9 2.8 2.3 7.3 0.1 2.4 2 0 0 2 2 2 0 BlaR1 peptidase M56 zf-MYND PF01753.18 OQR96560.1 - 1e-09 38.3 15.4 2.1e-09 37.3 15.4 1.6 1 0 0 1 1 1 1 MYND finger zf-C6H2 PF15801.5 OQR96560.1 - 0.046 14.0 8.6 0.11 12.9 8.6 1.6 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding Med20 PF08612.11 OQR96561.1 - 7.3e-09 35.3 0.0 9.8e-09 34.9 0.0 1.1 1 0 0 1 1 1 1 TATA-binding related factor (TRF) of subunit 20 of Mediator complex TPR_19 PF14559.6 OQR96562.1 - 0.00098 19.6 3.2 0.19 12.3 0.4 3.1 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 OQR96562.1 - 0.0012 19.5 0.6 0.13 13.2 0.1 3.7 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 OQR96562.1 - 0.003 18.2 0.5 2.3 8.9 0.0 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 OQR96562.1 - 0.0051 16.8 6.7 0.35 11.1 0.4 4.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.6 OQR96562.1 - 0.88 10.3 12.2 1.8 9.3 0.2 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat ANAPC3 PF12895.7 OQR96562.1 - 3.3 8.0 9.1 0.34 11.2 0.2 3.2 2 1 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_1 PF00515.28 OQR96562.1 - 4.7 7.2 10.6 9.3 6.3 0.1 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat Peptidase_M14 PF00246.24 OQR96563.1 - 2.5e-12 47.2 0.0 6.4e-12 45.9 0.0 1.7 1 0 0 1 1 1 1 Zinc carboxypeptidase Pepdidase_M14_N PF18027.1 OQR96563.1 - 3.7e-10 40.1 0.2 1.2e-09 38.5 0.2 1.9 1 0 0 1 1 1 1 Cytosolic carboxypeptidase N-terminal domain fn3 PF00041.21 OQR96563.1 - 0.028 14.8 0.4 3.1 8.2 0.0 2.9 2 0 0 2 2 2 0 Fibronectin type III domain NAD_binding_4 PF07993.12 OQR96563.1 - 0.52 9.4 3.4 1.1 8.4 3.4 1.5 1 0 0 1 1 1 0 Male sterility protein LAX PF15681.5 OQR96565.1 - 0.03 13.1 0.1 0.041 12.7 0.1 1.1 1 0 0 1 1 1 0 Lymphocyte activation family X 2OG-FeII_Oxy_3 PF13640.6 OQR96566.1 - 0.00069 20.5 0.0 0.0012 19.7 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DUF2207 PF09972.9 OQR96567.1 - 0.011 14.6 0.3 0.013 14.3 0.3 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Glycophorin_A PF01102.18 OQR96567.1 - 0.011 16.0 3.9 0.028 14.7 3.9 1.7 1 1 0 1 1 1 0 Glycophorin A Trp_oprn_chp PF09534.10 OQR96567.1 - 0.023 14.5 0.1 0.049 13.4 0.1 1.5 2 0 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) TMEM154 PF15102.6 OQR96567.1 - 0.048 13.6 4.6 0.1 12.5 4.6 1.5 1 0 0 1 1 1 0 TMEM154 protein family HCV_NS4a PF01006.20 OQR96567.1 - 0.078 12.7 0.3 0.18 11.6 0.3 1.6 1 0 0 1 1 1 0 Hepatitis C virus non-structural protein NS4a DUF4366 PF14283.6 OQR96567.1 - 0.16 12.0 1.1 0.25 11.4 1.1 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4366) SKG6 PF08693.10 OQR96567.1 - 7.9 6.0 11.5 1.8 8.1 7.5 1.9 2 0 0 2 2 2 0 Transmembrane alpha-helix domain Trm112p PF03966.16 OQR96589.1 - 0.00061 20.3 0.2 0.0029 18.2 0.0 2.2 2 0 0 2 2 2 1 Trm112p-like protein bZIP_1 PF00170.21 OQR96589.1 - 0.012 15.7 5.0 0.021 14.9 5.0 1.3 1 0 0 1 1 1 0 bZIP transcription factor bZIP_1 PF00170.21 OQR96590.1 - 0.064 13.4 2.4 0.14 12.2 2.4 1.5 1 0 0 1 1 1 0 bZIP transcription factor RSV_NS2 PF03113.14 OQR96590.1 - 0.091 12.8 0.2 0.17 11.9 0.2 1.5 1 0 0 1 1 1 0 Respiratory synctial virus non-structural protein NS2 MCR_D PF02505.14 OQR96590.1 - 0.11 12.3 0.5 7.3 6.4 0.0 2.9 3 0 0 3 3 3 0 Methyl-coenzyme M reductase operon protein D bZIP_2 PF07716.15 OQR96591.1 - 0.00011 22.2 15.0 0.024 14.7 5.5 2.4 2 0 0 2 2 2 2 Basic region leucine zipper bZIP_1 PF00170.21 OQR96591.1 - 0.00018 21.5 16.2 0.034 14.3 7.0 2.3 2 0 0 2 2 2 2 bZIP transcription factor CLZ PF16526.5 OQR96591.1 - 0.013 15.8 6.1 0.33 11.3 0.8 2.6 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Uds1 PF15456.6 OQR96591.1 - 0.021 15.0 2.1 3.4 7.8 0.6 2.3 2 0 0 2 2 2 0 Up-regulated During Septation AnmK PF03702.14 OQR96591.1 - 0.078 12.1 0.1 0.11 11.6 0.1 1.1 1 0 0 1 1 1 0 Anhydro-N-acetylmuramic acid kinase HAUS6_N PF14661.6 OQR96591.1 - 0.13 11.8 6.9 0.41 10.2 4.5 2.1 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus DUF1640 PF07798.11 OQR96591.1 - 0.52 10.3 6.8 0.26 11.3 1.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1640) RasGAP_C PF03836.15 OQR96591.1 - 2.2 8.4 7.8 9 6.4 0.6 2.3 2 0 0 2 2 2 0 RasGAP C-terminus zf-DBF PF07535.12 OQR96594.1 - 0.12 12.5 0.8 13 5.9 0.1 2.6 2 0 0 2 2 2 0 DBF zinc finger tRNA_synthFbeta PF17759.1 OQR96595.1 - 7.2e-47 159.6 0.0 1.5e-46 158.5 0.0 1.6 2 0 0 2 2 2 1 Phenylalanyl tRNA synthetase beta chain CLM domain PhetRS_B1 PF18262.1 OQR96595.1 - 6.5e-35 119.2 0.2 3.3e-33 113.7 0.1 2.7 2 0 0 2 2 2 1 Phe-tRNA synthetase beta subunit B1 domain Glyco_hydro_16 PF00722.21 OQR96595.1 - 2.4e-33 115.1 0.6 4.5e-33 114.2 0.6 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 B3_4 PF03483.17 OQR96595.1 - 3.4e-26 92.0 0.0 6.2e-26 91.1 0.0 1.4 1 0 0 1 1 1 1 B3/4 domain SKN1 PF03935.15 OQR96595.1 - 3.1e-17 62.2 5.4 3.1e-08 32.5 0.5 2.2 2 0 0 2 2 2 2 Beta-glucan synthesis-associated protein (SKN1) B5 PF03484.15 OQR96595.1 - 1.1e-12 48.1 0.1 9e-11 41.9 0.0 3.0 3 0 0 3 3 3 1 tRNA synthetase B5 domain tRNA-synt_2d PF01409.20 OQR96595.1 - 0.015 14.8 0.0 0.046 13.2 0.0 1.8 1 1 0 1 1 1 0 tRNA synthetases class II core domain (F) mRNA_cap_enzyme PF01331.19 OQR96596.1 - 3.8e-38 131.3 0.1 5.6e-38 130.7 0.1 1.2 1 0 0 1 1 1 1 mRNA capping enzyme, catalytic domain DNA_ligase_A_M PF01068.21 OQR96596.1 - 0.00017 21.3 0.0 0.0018 18.0 0.0 2.0 1 1 1 2 2 2 1 ATP dependent DNA ligase domain DSPc PF00782.20 OQR96596.1 - 0.00096 19.0 0.0 0.0017 18.2 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain FYVE PF01363.21 OQR96610.1 - 2.2e-17 63.0 27.4 1.2e-08 35.0 11.1 2.8 2 0 0 2 2 2 2 FYVE zinc finger START PF01852.19 OQR96610.1 - 2.5e-16 59.7 0.1 4e-07 29.7 0.0 2.4 2 0 0 2 2 2 2 START domain FYVE_2 PF02318.16 OQR96610.1 - 1.9e-08 34.6 17.5 0.00053 20.2 5.9 2.8 2 0 0 2 2 2 2 FYVE-type zinc finger IBR PF01485.21 OQR96610.1 - 0.01 16.1 19.3 0.065 13.5 2.1 3.3 2 1 0 2 2 2 0 IBR domain, a half RING-finger domain C1_1 PF00130.22 OQR96610.1 - 0.063 13.2 21.6 0.29 11.0 6.7 2.7 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) C1_2 PF03107.16 OQR96610.1 - 0.067 13.5 17.8 1.2 9.5 2.7 2.9 2 0 0 2 2 2 0 C1 domain zf-HIT PF04438.16 OQR96610.1 - 3.7 7.5 26.5 2.5 8.1 7.4 2.8 2 0 0 2 2 2 0 HIT zinc finger DUF4215 PF13948.6 OQR96610.1 - 6.8 7.2 7.5 14 6.3 3.8 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF4215) FYVE PF01363.21 OQR96611.1 - 4.8e-10 39.4 8.9 1.1e-09 38.3 8.9 1.5 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.16 OQR96611.1 - 0.00014 22.1 4.5 0.00029 21.0 4.5 1.4 1 0 0 1 1 1 1 FYVE-type zinc finger START PF01852.19 OQR96611.1 - 0.027 13.9 0.0 0.05 13.0 0.0 1.3 1 0 0 1 1 1 0 START domain IBR PF01485.21 OQR96611.1 - 0.93 9.8 7.8 0.35 11.1 4.4 2.0 2 0 0 2 2 2 0 IBR domain, a half RING-finger domain Abhydrolase_2 PF02230.16 OQR96612.1 - 8.8e-53 179.3 0.1 1e-52 179.1 0.1 1.0 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.21 OQR96612.1 - 1.1e-06 28.3 0.6 2.4e-05 23.9 0.0 2.3 1 1 1 2 2 2 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 OQR96612.1 - 1.9e-05 24.0 2.4 0.0018 17.6 0.0 2.9 2 1 0 3 3 3 1 Serine aminopeptidase, S33 FSH1 PF03959.13 OQR96612.1 - 2e-05 24.4 0.0 8.6e-05 22.3 0.0 1.8 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.7 OQR96612.1 - 5.7e-05 23.8 0.1 0.00019 22.1 0.2 1.6 1 1 1 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.13 OQR96612.1 - 0.00024 21.1 0.2 0.019 14.8 0.0 2.1 1 1 1 2 2 2 1 alpha/beta hydrolase fold DLH PF01738.18 OQR96612.1 - 0.0018 17.8 0.0 0.0029 17.2 0.0 1.3 1 0 0 1 1 1 1 Dienelactone hydrolase family Esterase_phd PF10503.9 OQR96612.1 - 0.011 15.3 0.1 3.1 7.2 0.2 2.3 1 1 1 2 2 2 0 Esterase PHB depolymerase LIP PF03583.14 OQR96612.1 - 0.024 13.9 0.2 0.93 8.7 0.0 2.3 1 1 0 2 2 2 0 Secretory lipase Abhydrolase_5 PF12695.7 OQR96612.1 - 0.036 13.8 0.0 0.058 13.2 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Cadherin_5 PF17892.1 OQR96612.1 - 0.049 13.6 0.1 0.091 12.7 0.1 1.4 1 0 0 1 1 1 0 Cadherin-like domain Cutinase PF01083.22 OQR96612.1 - 0.1 12.5 0.0 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 Cutinase Sugar_tr PF00083.24 OQR96613.1 - 1.5e-37 129.6 23.2 2.2e-37 129.0 23.2 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OQR96613.1 - 8.9e-28 97.2 40.2 1.5e-21 76.7 23.6 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Telomere_reg-2 PF10193.9 OQR96613.1 - 4.6e-19 68.9 0.3 2.4e-18 66.6 0.1 2.3 2 0 0 2 2 2 1 Telomere length regulation protein Ion_trans PF00520.31 OQR96614.1 - 0.00049 19.4 12.8 0.00067 19.0 12.8 1.2 1 0 0 1 1 1 1 Ion transport protein SLAC1 PF03595.17 OQR96614.1 - 0.0092 15.3 8.0 0.017 14.4 7.7 1.5 1 1 0 1 1 1 1 Voltage-dependent anion channel Spo7 PF03907.13 OQR96614.1 - 4.1 6.8 6.3 11 5.4 6.3 1.7 1 1 0 1 1 1 0 Spo7-like protein Rubis-subs-bind PF09273.11 OQR96615.1 - 4.7e-13 49.9 0.0 8.9e-13 49.1 0.0 1.4 1 0 0 1 1 1 1 Rubisco LSMT substrate-binding SET PF00856.28 OQR96615.1 - 4.8e-09 36.8 0.0 8.8e-09 36.0 0.0 1.5 1 0 0 1 1 1 1 SET domain Aa_trans PF01490.18 OQR96616.1 - 1.3e-38 132.8 27.0 1.7e-38 132.4 27.0 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Sec23_trunk PF04811.15 OQR96617.1 - 2.2e-43 148.6 0.0 3.2e-43 148.1 0.0 1.2 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.15 OQR96617.1 - 2e-17 62.9 0.0 5.3e-17 61.5 0.0 1.8 1 1 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.12 OQR96617.1 - 1.2e-15 58.0 0.0 2.3e-15 57.1 0.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.15 OQR96617.1 - 3.4e-14 52.6 3.4 1e-13 51.1 3.4 1.9 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 OQR96617.1 - 0.0084 16.0 0.0 0.02 14.8 0.0 1.7 1 0 0 1 1 1 1 Gelsolin repeat Elicitin PF00964.17 OQR96618.1 - 3.1e-05 24.0 6.3 0.05 13.7 1.4 2.9 2 1 1 3 3 3 3 Elicitin MoaE PF02391.17 OQR96619.1 - 9.5e-24 83.9 0.0 1.8e-23 82.9 0.0 1.5 1 0 0 1 1 1 1 MoaE protein IBR PF01485.21 OQR96619.1 - 1.8e-12 47.3 33.4 8.6e-08 32.3 9.5 4.3 4 0 0 4 4 4 3 IBR domain, a half RING-finger domain zf-RING_2 PF13639.6 OQR96619.1 - 1.1e-06 28.8 3.1 1.1e-06 28.8 3.1 4.4 4 0 0 4 4 4 1 Ring finger domain ENTH PF01417.20 OQR96619.1 - 3.4e-06 27.1 0.0 7e-06 26.1 0.0 1.5 1 0 0 1 1 1 1 ENTH domain zf-C3HC4_2 PF13923.6 OQR96619.1 - 9.6e-06 25.3 1.2 9.6e-06 25.3 1.2 4.5 6 0 0 6 6 6 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 OQR96619.1 - 4.7e-05 23.2 4.1 4.7e-05 23.2 4.1 3.8 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 OQR96619.1 - 0.00072 19.7 5.4 0.00072 19.7 5.4 4.5 5 1 0 5 5 5 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 OQR96619.1 - 0.0041 17.1 3.7 0.0041 17.1 3.7 4.9 4 1 1 5 5 5 1 zinc-RING finger domain Methyltransf_11 PF08241.12 OQR96620.1 - 2.6e-14 53.6 0.0 7.4e-14 52.2 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 OQR96620.1 - 1.5e-12 48.1 0.0 3.9e-12 46.7 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 OQR96620.1 - 1e-06 28.7 0.0 1.6e-06 28.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OQR96620.1 - 9e-05 23.2 0.0 0.00019 22.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OQR96620.1 - 0.0018 18.1 0.0 0.0044 16.8 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain FYVE PF01363.21 OQR96621.1 - 1e-25 89.6 31.8 2.2e-14 53.3 10.7 2.4 2 0 0 2 2 2 2 FYVE zinc finger GAF PF01590.26 OQR96621.1 - 9.7e-10 39.2 0.1 7.5e-09 36.3 0.0 2.4 2 0 0 2 2 2 1 GAF domain FYVE_2 PF02318.16 OQR96621.1 - 0.00018 21.7 25.7 0.0033 17.6 8.5 2.5 2 0 0 2 2 2 2 FYVE-type zinc finger C1_2 PF03107.16 OQR96621.1 - 0.052 13.9 23.1 1 9.7 8.4 2.7 2 0 0 2 2 2 0 C1 domain Pkinase_Tyr PF07714.17 OQR96643.1 - 4.4e-29 101.6 0.0 6.2e-29 101.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OQR96643.1 - 1.1e-26 93.8 0.0 1.7e-26 93.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Adeno_E3_CR2 PF02439.15 OQR96643.1 - 6.2e-05 22.7 0.0 0.00018 21.2 0.0 1.8 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 SKG6 PF08693.10 OQR96643.1 - 0.0034 16.7 2.2 0.0094 15.3 2.2 1.8 1 0 0 1 1 1 1 Transmembrane alpha-helix domain TMEM72 PF16054.5 OQR96643.1 - 0.015 15.0 0.4 0.75 9.5 0.0 2.3 2 0 0 2 2 2 0 Transmembrane protein family 72 Syndecan PF01034.20 OQR96643.1 - 0.049 13.6 0.1 0.049 13.6 0.1 2.1 2 0 0 2 2 1 0 Syndecan domain DUF3827 PF12877.7 OQR96643.1 - 0.076 11.4 0.0 0.11 10.9 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) Haspin_kinase PF12330.8 OQR96643.1 - 0.11 11.4 0.0 0.44 9.4 0.0 1.8 2 0 0 2 2 2 0 Haspin like kinase domain RIFIN PF02009.16 OQR96643.1 - 0.14 12.0 0.4 0.25 11.2 0.2 1.4 1 1 0 1 1 1 0 Rifin Kdo PF06293.14 OQR96643.1 - 0.2 11.0 0.0 0.41 10.0 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Gram_pos_anchor PF00746.21 OQR96643.1 - 0.32 11.0 2.1 0.97 9.4 0.2 2.6 3 0 0 3 3 3 0 LPXTG cell wall anchor motif EphA2_TM PF14575.6 OQR96643.1 - 5.1 8.1 6.4 1.5 9.7 0.1 2.9 3 1 0 3 3 3 0 Ephrin type-A receptor 2 transmembrane domain Ricin_B_lectin PF00652.22 OQR96644.1 - 5.8e-26 91.2 18.5 1.1e-12 48.2 4.6 3.1 2 1 1 3 3 3 3 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.6 OQR96644.1 - 7.9e-11 42.5 20.7 0.0047 17.6 1.1 5.0 3 2 2 5 5 5 4 Ricin-type beta-trefoil lectin domain-like CDtoxinA PF03498.14 OQR96644.1 - 0.00013 21.6 0.2 0.023 14.3 0.0 2.5 2 0 0 2 2 2 2 Cytolethal distending toxin A/C domain SUKH_6 PF14568.6 OQR96644.1 - 0.047 14.1 0.8 15 6.0 0.2 3.6 3 0 0 3 3 3 0 SMI1-KNR4 cell-wall OCRE PF17780.1 OQR96644.1 - 2.1 8.5 9.6 12 6.1 0.1 3.4 2 1 0 2 2 2 0 OCRE domain ABC2_membrane PF01061.24 OQR96646.1 - 3.7e-35 121.3 17.3 5.4e-35 120.7 17.3 1.3 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.27 OQR96646.1 - 4.3e-26 92.1 0.0 6.9e-26 91.4 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 OQR96646.1 - 6.9e-10 39.2 0.2 3.7e-05 23.7 0.1 2.3 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 OQR96646.1 - 0.00054 19.5 0.0 0.0021 17.5 0.0 1.9 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 OQR96646.1 - 0.00074 19.5 0.0 0.0013 18.7 0.0 1.3 1 0 0 1 1 1 1 RsgA GTPase AAA_16 PF13191.6 OQR96646.1 - 0.0012 19.3 0.0 0.0022 18.4 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 OQR96646.1 - 0.0025 17.5 0.1 0.0053 16.5 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 OQR96646.1 - 0.078 13.1 0.0 0.22 11.6 0.0 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase ABC2_membrane_3 PF12698.7 OQR96646.1 - 0.096 11.8 15.6 0.077 12.1 14.4 1.5 1 1 0 1 1 1 0 ABC-2 family transporter protein AAA_23 PF13476.6 OQR96646.1 - 0.17 12.4 0.0 0.27 11.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain DUF1192 PF06698.11 OQR96647.1 - 0.004 17.2 0.8 4.1 7.5 0.0 2.9 2 0 0 2 2 2 2 Protein of unknown function (DUF1192) MPS2 PF17060.5 OQR96647.1 - 0.016 14.5 5.1 0.023 14.0 5.1 1.2 1 0 0 1 1 1 0 Monopolar spindle protein 2 GIT_CC PF16559.5 OQR96647.1 - 0.11 12.3 2.4 0.12 12.2 0.6 2.0 2 0 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor NRBF2 PF08961.10 OQR96647.1 - 0.19 11.3 7.3 0.058 13.0 3.3 2.0 1 1 0 1 1 1 0 Nuclear receptor-binding factor 2, autophagy regulator SOGA PF11365.8 OQR96647.1 - 0.23 12.6 9.1 15 6.8 5.8 3.6 2 1 1 3 3 3 0 Protein SOGA CRR7 PF12095.8 OQR96647.1 - 0.32 11.5 2.1 0.86 10.1 0.3 2.6 1 1 0 2 2 2 0 Protein CHLORORESPIRATORY REDUCTION 7 Mvb12 PF09452.10 OQR96647.1 - 0.58 10.6 5.1 10 6.6 0.8 2.9 3 0 0 3 3 3 0 ESCRT-I subunit Mvb12 bZIP_1 PF00170.21 OQR96647.1 - 0.62 10.2 5.2 0.43 10.7 0.6 2.9 2 1 1 3 3 3 0 bZIP transcription factor DivIC PF04977.15 OQR96647.1 - 1.1 9.1 11.0 0.065 13.0 2.1 2.5 2 0 0 2 2 2 0 Septum formation initiator FAM76 PF16046.5 OQR96647.1 - 6.5 6.0 10.7 14 4.9 10.7 1.6 1 0 0 1 1 1 0 FAM76 protein TMF_DNA_bd PF12329.8 OQR96647.1 - 7.4 6.6 12.8 18 5.4 3.3 2.9 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding F5_F8_type_C PF00754.25 OQR96649.1 - 0.0021 18.2 0.3 0.0032 17.6 0.3 1.3 1 0 0 1 1 1 1 F5/8 type C domain Gon7 PF08738.10 OQR96650.1 - 0.068 13.3 0.2 0.068 13.3 0.2 1.8 2 0 0 2 2 2 0 Gon7 family DUF150 PF02576.17 OQR96650.1 - 0.11 13.0 0.3 0.39 11.2 0.0 2.0 2 0 0 2 2 2 0 RimP N-terminal domain DUF3665 PF12427.8 OQR96650.1 - 1.6 8.5 4.4 1.3 8.8 0.6 2.5 2 0 0 2 2 2 0 Branched-chain amino acid aminotransferase ABC_membrane PF00664.23 OQR96651.1 - 1.9e-54 185.2 4.2 1.9e-54 185.2 4.2 1.9 2 0 0 2 2 2 1 ABC transporter transmembrane region ABC_tran PF00005.27 OQR96651.1 - 4.3e-36 124.4 0.0 8.2e-36 123.5 0.0 1.5 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 OQR96651.1 - 1e-05 25.1 0.4 0.0004 19.9 0.0 2.1 1 1 1 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 OQR96651.1 - 0.0051 17.1 0.0 0.025 14.9 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 OQR96651.1 - 0.016 15.6 0.1 0.035 14.5 0.1 1.5 1 1 0 1 1 1 0 AAA ATPase domain AAA PF00004.29 OQR96651.1 - 0.04 14.3 2.2 0.68 10.4 1.0 2.7 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.12 OQR96651.1 - 0.041 13.2 0.0 0.078 12.3 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin G-alpha PF00503.20 OQR96651.1 - 0.061 12.5 0.0 0.099 11.8 0.0 1.2 1 0 0 1 1 1 0 G-protein alpha subunit AAA_29 PF13555.6 OQR96651.1 - 0.073 12.8 0.1 0.19 11.5 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_25 PF13481.6 OQR96651.1 - 0.077 12.6 0.1 0.36 10.4 0.0 2.0 2 0 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 OQR96651.1 - 0.078 12.9 0.1 0.16 11.8 0.1 1.4 1 0 0 1 1 1 0 RsgA GTPase AAA_15 PF13175.6 OQR96651.1 - 0.095 12.4 0.0 0.14 11.8 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain SbcCD_C PF13558.6 OQR96651.1 - 0.11 12.8 0.2 1.7 8.9 0.2 2.4 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit Ni_hydr_CYTB PF01292.20 OQR96651.1 - 1.1 8.8 5.0 4.9 6.7 5.0 2.2 1 1 0 1 1 1 0 Prokaryotic cytochrome b561 SpoIIIAH PF12685.7 OQR96652.1 - 0.02 14.8 0.0 0.022 14.6 0.0 1.1 1 0 0 1 1 1 0 SpoIIIAH-like protein Adeno_E3_CR2 PF02439.15 OQR96652.1 - 0.021 14.6 0.2 0.036 13.8 0.2 1.3 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 TMEM154 PF15102.6 OQR96652.1 - 0.033 14.1 2.2 0.13 12.2 0.0 2.2 2 0 0 2 2 2 0 TMEM154 protein family Gram_pos_anchor PF00746.21 OQR96652.1 - 0.039 13.9 0.9 0.074 13.0 0.9 1.4 1 0 0 1 1 1 0 LPXTG cell wall anchor motif Mem_trans PF03547.18 OQR96652.1 - 0.96 7.8 3.5 10 4.4 1.7 2.0 2 0 0 2 2 2 0 Membrane transport protein SR-25 PF10500.9 OQR96652.1 - 3.8 7.1 12.6 6.2 6.4 12.6 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Ank_5 PF13857.6 OQR96653.1 - 1.4e-15 57.2 6.5 1.1e-08 35.2 1.0 3.4 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 OQR96653.1 - 4.2e-14 52.9 2.9 1e-13 51.7 2.8 1.7 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OQR96653.1 - 2.3e-12 45.9 5.9 0.00027 21.1 0.1 3.5 3 0 0 3 3 3 3 Ankyrin repeat Ank_4 PF13637.6 OQR96653.1 - 1.9e-10 41.1 5.9 3.6e-05 24.2 0.5 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 OQR96653.1 - 4.4e-10 39.6 8.7 0.00086 19.7 0.1 3.5 3 0 0 3 3 3 3 Ankyrin repeat HAT_KAT11 PF08214.11 OQR96654.1 - 6.3e-20 71.8 0.3 1.1e-19 71.0 0.3 1.3 1 0 0 1 1 1 1 Histone acetylation protein Bromodomain PF00439.25 OQR96654.1 - 2.5e-15 56.3 0.0 8.3e-15 54.6 0.0 1.9 1 0 0 1 1 1 1 Bromodomain PHD PF00628.29 OQR96654.1 - 0.001 18.9 5.1 0.001 18.9 5.1 4.2 3 2 0 3 3 3 1 PHD-finger ABC_membrane PF00664.23 OQR96655.1 - 1.9e-53 181.9 6.9 3.5e-53 181.0 6.9 1.3 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 OQR96655.1 - 1.6e-34 119.4 0.0 2.8e-34 118.6 0.0 1.4 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 OQR96655.1 - 3.9e-05 23.2 0.4 0.0028 17.1 0.0 2.2 1 1 1 2 2 2 1 RecF/RecN/SMC N terminal domain Zeta_toxin PF06414.12 OQR96655.1 - 0.0013 18.1 0.0 0.0025 17.1 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin ABC_ATPase PF09818.9 OQR96655.1 - 0.0039 16.1 0.3 0.028 13.2 0.1 2.1 2 0 0 2 2 2 1 Predicted ATPase of the ABC class AAA_29 PF13555.6 OQR96655.1 - 0.0044 16.7 0.0 0.012 15.4 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_15 PF13175.6 OQR96655.1 - 0.018 14.8 0.0 0.023 14.4 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain AAA_30 PF13604.6 OQR96655.1 - 0.019 14.7 0.5 0.069 12.9 0.5 2.0 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.6 OQR96655.1 - 0.031 14.7 0.0 0.061 13.7 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain RsgA_GTPase PF03193.16 OQR96655.1 - 0.033 14.1 0.0 0.074 12.9 0.0 1.6 1 0 0 1 1 1 0 RsgA GTPase AAA_21 PF13304.6 OQR96655.1 - 0.037 13.8 0.2 1.7 8.4 0.1 2.2 1 1 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 OQR96655.1 - 0.042 14.1 0.1 0.23 11.7 0.1 2.1 1 1 0 1 1 1 0 AAA domain G-alpha PF00503.20 OQR96655.1 - 0.086 12.0 0.0 0.12 11.5 0.0 1.3 1 0 0 1 1 1 0 G-protein alpha subunit DUF4397 PF14344.6 OQR96655.1 - 0.11 13.3 2.0 0.27 12.0 1.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4397) Ni_hydr_CYTB PF01292.20 OQR96655.1 - 1.1 8.8 6.4 5.8 6.5 6.4 2.2 1 1 0 1 1 1 0 Prokaryotic cytochrome b561 APH PF01636.23 OQR96662.1 - 9.8e-11 42.0 3.3 7.5e-10 39.1 3.2 2.1 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kinesin PF00225.23 OQR96663.1 - 3e-84 282.8 0.0 4.6e-84 282.2 0.0 1.3 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 OQR96663.1 - 5.6e-20 71.8 0.0 3.6e-19 69.2 0.0 2.4 3 0 0 3 3 3 1 Microtubule binding WW PF00397.26 OQR96663.1 - 5.6e-08 32.7 3.8 1.1e-07 31.8 3.8 1.5 1 0 0 1 1 1 1 WW domain Proteasome PF00227.26 OQR96664.1 - 1e-41 142.6 0.0 1.5e-41 142.0 0.0 1.3 1 0 0 1 1 1 1 Proteasome subunit Sad1_UNC PF07738.13 OQR96664.1 - 9.2e-24 83.9 0.1 4.2e-23 81.8 0.0 1.9 2 0 0 2 2 2 1 Sad1 / UNC-like C-terminal DUF1180 PF06679.12 OQR96664.1 - 0.011 16.1 0.1 0.011 16.1 0.1 2.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1180) UPF0242 PF06785.11 OQR96664.1 - 0.034 14.3 0.6 0.092 12.8 0.6 1.7 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus SlyX PF04102.12 OQR96664.1 - 0.078 13.6 1.1 0.18 12.4 1.1 1.6 1 0 0 1 1 1 0 SlyX UCH PF00443.29 OQR96665.1 - 6.6e-43 147.1 0.0 8.9e-43 146.6 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 OQR96665.1 - 1.2e-14 54.6 5.1 1.3e-13 51.3 5.1 2.1 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Pkinase_Tyr PF07714.17 OQR96667.1 - 3.9e-47 160.7 0.0 4.6e-47 160.5 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OQR96667.1 - 2.2e-35 122.3 0.0 3e-35 121.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 OQR96667.1 - 0.013 14.8 0.0 0.029 13.7 0.0 1.5 2 0 0 2 2 2 0 Kinase-like CTNNBL PF08216.11 OQR96668.1 - 1.9e-27 95.5 1.2 1.9e-27 95.5 1.2 2.1 2 0 0 2 2 2 1 Catenin-beta-like, Arm-motif containing nuclear Arm PF00514.23 OQR96668.1 - 0.00056 19.8 0.3 0.04 14.0 0.0 3.9 4 0 0 4 4 4 1 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 OQR96668.1 - 0.025 15.0 1.5 1.2 9.5 0.1 3.9 3 1 1 4 4 4 0 HEAT repeats HEAT PF02985.22 OQR96668.1 - 0.1 12.9 0.1 22 5.7 0.0 3.7 2 0 0 2 2 2 0 HEAT repeat ZnuA PF01297.17 OQR96668.1 - 0.13 11.6 0.8 0.23 10.8 0.1 1.8 2 0 0 2 2 2 0 Zinc-uptake complex component A periplasmic Metallophos_2 PF12850.7 OQR96672.1 - 9.4e-25 87.7 0.1 1.1e-24 87.5 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.28 OQR96672.1 - 6.5e-05 23.5 1.2 0.1 13.1 0.1 2.2 1 1 1 2 2 2 2 Calcineurin-like phosphoesterase GDPD PF03009.17 OQR96672.1 - 0.03 14.1 0.0 0.034 13.9 0.0 1.2 1 0 0 1 1 1 0 Glycerophosphoryl diester phosphodiesterase family LRR_4 PF12799.7 OQR96674.1 - 7.6e-19 67.5 21.4 3.6e-07 30.4 2.5 3.7 3 0 0 3 3 3 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 OQR96674.1 - 1.5e-15 56.7 17.7 4.7e-09 35.9 1.2 2.8 2 1 0 2 2 2 2 Leucine rich repeat LRR_9 PF14580.6 OQR96674.1 - 4.9e-13 49.0 9.5 1.1e-09 38.0 3.0 2.5 1 1 1 2 2 2 2 Leucine-rich repeat LRR_6 PF13516.6 OQR96674.1 - 3.4e-07 29.8 15.1 0.046 13.8 0.0 6.1 6 0 0 6 6 6 2 Leucine Rich repeat LRR_1 PF00560.33 OQR96674.1 - 0.00081 19.6 15.0 21 6.2 0.1 6.5 5 1 1 6 6 6 1 Leucine Rich Repeat Methyltransf_16 PF10294.9 OQR96701.1 - 5.7e-30 104.3 0.1 7.9e-30 103.9 0.1 1.2 1 0 0 1 1 1 1 Lysine methyltransferase PrmA PF06325.13 OQR96701.1 - 2.5e-07 30.4 0.0 4.2e-07 29.6 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 OQR96701.1 - 2.3e-05 24.0 0.0 3.8e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_31 PF13847.6 OQR96701.1 - 0.0011 18.8 0.0 0.0018 18.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OQR96701.1 - 0.0012 18.8 0.0 0.0018 18.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OQR96701.1 - 0.0015 19.2 0.0 0.0031 18.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OQR96701.1 - 0.0051 17.4 0.0 0.0099 16.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.15 OQR96701.1 - 0.061 13.0 0.0 0.093 12.4 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Met_10 PF02475.16 OQR96701.1 - 0.076 12.7 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 Met-10+ like-protein DUF3617 PF12276.8 OQR96702.1 - 0.025 14.9 0.6 0.069 13.5 0.6 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3617) zf-CCCH_4 PF18044.1 OQR96703.1 - 1.5e-24 85.2 39.1 4.9e-07 29.4 5.1 4.5 4 0 0 4 4 4 4 CCCH-type zinc finger zf_CCCH_4 PF18345.1 OQR96703.1 - 1.3e-14 53.7 44.7 4.2e-05 23.5 5.3 4.8 4 1 0 4 4 4 4 Zinc finger domain Torus PF16131.5 OQR96703.1 - 2.4e-12 47.5 17.1 0.0073 17.0 0.2 4.3 3 1 1 4 4 4 4 Torus domain zf-CCCH PF00642.24 OQR96703.1 - 7.3e-11 41.7 41.7 8.4e-05 22.4 3.9 4.5 3 1 1 4 4 4 4 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-RING_5 PF14634.6 OQR96703.1 - 3.7e-07 30.0 4.4 3.7e-07 30.0 4.4 2.6 3 0 0 3 3 2 1 zinc-RING finger domain zf-C3HC4 PF00097.25 OQR96703.1 - 5.3e-05 23.0 4.2 5.3e-05 23.0 4.2 3.0 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-CCCH_3 PF15663.5 OQR96703.1 - 0.00012 22.3 19.7 0.076 13.2 2.1 4.1 3 1 1 4 4 4 3 Zinc-finger containing family zf-RING_2 PF13639.6 OQR96703.1 - 0.00018 21.8 5.1 0.00018 21.8 5.1 4.0 4 1 0 4 4 4 1 Ring finger domain zf-C3HC4_2 PF13923.6 OQR96703.1 - 0.00019 21.2 5.0 0.00019 21.2 5.0 3.0 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-UDP PF14569.6 OQR96703.1 - 0.0014 18.7 3.8 0.0037 17.3 3.8 1.7 1 0 0 1 1 1 1 Zinc-binding RING-finger zf-RING_UBOX PF13445.6 OQR96703.1 - 0.0047 16.9 0.7 0.0047 16.9 0.7 2.9 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_11 PF17123.5 OQR96703.1 - 0.0088 15.8 1.8 0.0088 15.8 1.8 3.1 3 1 0 3 3 3 1 RING-like zinc finger zf-CCCH_2 PF14608.6 OQR96703.1 - 0.12 12.9 44.3 0.12 12.8 1.8 5.1 5 0 0 5 5 5 0 RNA-binding, Nab2-type zinc finger zf-C3HC4_4 PF15227.6 OQR96703.1 - 0.95 9.7 9.1 0.61 10.3 4.6 2.9 2 1 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-C3HC4_5 PF17121.5 OQR96703.1 - 8.6 6.3 15.1 1.3 9.0 7.9 3.1 2 1 1 3 3 3 0 Zinc finger, C3HC4 type (RING finger) DUSP PF06337.12 OQR96704.1 - 1.4e-08 35.2 0.1 3.7e-08 33.9 0.1 1.7 1 0 0 1 1 1 1 DUSP domain C2 PF00168.30 OQR96704.1 - 0.00066 19.9 0.0 0.0016 18.7 0.0 1.7 1 0 0 1 1 1 1 C2 domain HEAT_EZ PF13513.6 OQR96704.1 - 0.0042 17.6 0.3 3.8 8.1 0.0 4.1 3 0 0 3 3 3 1 HEAT-like repeat HEAT PF02985.22 OQR96704.1 - 0.0056 16.8 0.3 2.5 8.6 0.1 4.2 3 0 0 3 3 3 1 HEAT repeat HEAT_2 PF13646.6 OQR96704.1 - 0.023 15.1 0.2 0.47 10.9 0.0 3.2 2 1 0 2 2 2 0 HEAT repeats DUF383 PF04063.14 OQR96704.1 - 0.029 14.1 14.8 0.91 9.2 2.2 5.5 5 1 0 5 5 5 0 Domain of unknown function (DUF383) Vac14_Fab1_bd PF12755.7 OQR96704.1 - 0.089 13.4 0.4 9 7.0 0.1 3.7 3 0 0 3 3 3 0 Vacuolar 14 Fab1-binding region IBN_N PF03810.19 OQR96704.1 - 0.18 11.8 1.6 1.3 9.0 0.2 3.4 2 0 0 2 2 2 0 Importin-beta N-terminal domain MARVEL PF01284.23 OQR96705.1 - 0.0059 16.6 17.5 0.0094 16.0 17.5 1.3 1 0 0 1 1 1 1 Membrane-associating domain Met_gamma_lyase PF06838.11 OQR96705.1 - 0.076 11.5 0.0 0.092 11.2 0.0 1.2 1 0 0 1 1 1 0 Methionine gamma-lyase EF-hand_6 PF13405.6 OQR96706.1 - 0.024 14.5 0.7 1.2 9.2 0.1 2.9 2 0 0 2 2 2 0 EF-hand domain EF-hand_7 PF13499.6 OQR96706.1 - 0.047 14.2 1.4 9.3 6.8 0.2 3.5 2 1 1 3 3 3 0 EF-hand domain pair CrgA PF06781.12 OQR96706.1 - 0.2 11.7 1.8 19 5.4 0.3 2.8 2 0 0 2 2 2 0 Cell division protein CrgA DUF641 PF04859.12 OQR96706.1 - 0.41 11.0 8.3 0.46 10.8 0.1 3.2 3 1 1 4 4 4 0 Plant protein of unknown function (DUF641) Fumarate_red_D PF02313.17 OQR96706.1 - 5.2 7.2 7.6 2.4 8.3 2.9 2.8 2 1 1 3 3 3 0 Fumarate reductase subunit D Mito_carr PF00153.27 OQR96722.1 - 6e-33 112.6 0.2 9.5e-18 63.9 0.1 2.1 2 0 0 2 2 2 2 Mitochondrial carrier protein ELMO_CED12 PF04727.13 OQR96723.1 - 3.9e-24 85.7 0.0 2.5e-23 83.1 0.0 2.5 2 0 0 2 2 2 1 ELMO/CED-12 family RhoGAP PF00620.27 OQR96723.1 - 1.3e-22 80.3 0.1 1e-21 77.3 0.0 2.7 2 0 0 2 2 2 1 RhoGAP domain RUN PF02759.19 OQR96723.1 - 5.7e-14 52.2 0.1 5.7e-14 52.2 0.1 3.0 3 0 0 3 3 3 1 RUN domain Golgin_A5 PF09787.9 OQR96723.1 - 1.9e-09 37.4 29.9 1.9e-09 37.4 29.9 5.1 3 1 3 6 6 6 3 Golgin subfamily A member 5 Shugoshin_N PF07558.11 OQR96723.1 - 0.027 14.3 4.1 0.42 10.5 0.3 3.5 2 0 0 2 2 2 0 Shugoshin N-terminal coiled-coil region HALZ PF02183.18 OQR96723.1 - 5.6 7.3 14.9 0.24 11.6 0.4 4.7 5 0 0 5 5 5 0 Homeobox associated leucine zipper Baculo_PEP_C PF04513.12 OQR96723.1 - 7.4 6.6 21.6 6.7 6.8 6.5 3.9 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus AAA_25 PF13481.6 OQR96724.1 - 1.9e-23 83.1 0.0 3.4e-23 82.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain Toprim_2 PF13155.6 OQR96724.1 - 2.3e-09 37.5 0.0 5.8e-09 36.3 0.0 1.7 1 0 0 1 1 1 1 Toprim-like DnaB_C PF03796.15 OQR96724.1 - 3.2e-08 33.2 0.0 5.4e-08 32.5 0.0 1.3 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain ATPase PF06745.13 OQR96724.1 - 3.7e-07 29.7 0.0 6.6e-07 28.9 0.0 1.3 1 0 0 1 1 1 1 KaiC AAA_22 PF13401.6 OQR96724.1 - 7.6e-07 29.5 0.1 4.2e-06 27.1 0.0 2.3 1 1 1 2 2 2 1 AAA domain Toprim_3 PF13362.6 OQR96724.1 - 3.6e-05 24.0 0.0 0.00031 21.1 0.0 2.3 2 0 0 2 2 2 1 Toprim domain AAA_16 PF13191.6 OQR96724.1 - 6.3e-05 23.4 0.0 0.00015 22.2 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain ABC_tran PF00005.27 OQR96724.1 - 0.00028 21.4 0.0 0.00076 20.0 0.0 1.8 1 0 0 1 1 1 1 ABC transporter zf-CHC2 PF01807.20 OQR96724.1 - 0.00077 19.2 0.1 0.0017 18.1 0.1 1.5 1 0 0 1 1 1 1 CHC2 zinc finger IstB_IS21 PF01695.17 OQR96724.1 - 0.0012 18.6 0.0 0.0023 17.7 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein Toprim_4 PF13662.6 OQR96724.1 - 0.0019 18.6 0.0 0.0065 16.9 0.0 2.0 2 0 0 2 2 1 1 Toprim domain AAA_23 PF13476.6 OQR96724.1 - 0.0042 17.6 1.5 0.0051 17.3 0.1 1.8 2 0 0 2 2 1 1 AAA domain NACHT PF05729.12 OQR96724.1 - 0.0048 16.8 0.2 0.011 15.6 0.2 1.6 1 0 0 1 1 1 1 NACHT domain RsgA_GTPase PF03193.16 OQR96724.1 - 0.0051 16.7 0.0 0.011 15.6 0.0 1.6 1 0 0 1 1 1 1 RsgA GTPase AAA_28 PF13521.6 OQR96724.1 - 0.0065 16.7 0.1 0.016 15.5 0.1 1.7 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.6 OQR96724.1 - 0.012 15.7 0.2 0.049 13.7 0.2 2.2 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.6 OQR96724.1 - 0.013 15.2 0.2 0.05 13.4 0.2 2.0 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA PF00004.29 OQR96724.1 - 0.018 15.5 0.8 0.17 12.3 0.1 2.7 2 1 1 3 3 2 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 OQR96724.1 - 0.018 14.5 0.3 0.084 12.3 0.0 2.1 3 0 0 3 3 3 0 PhoH-like protein RNA_helicase PF00910.22 OQR96724.1 - 0.019 15.3 0.0 0.1 13.0 0.0 2.2 2 0 0 2 2 2 0 RNA helicase AAA_30 PF13604.6 OQR96724.1 - 0.021 14.5 0.0 0.041 13.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain cobW PF02492.19 OQR96724.1 - 0.021 14.4 0.2 0.043 13.4 0.2 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain Rad17 PF03215.15 OQR96724.1 - 0.027 14.4 0.0 0.053 13.4 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain ATPase_2 PF01637.18 OQR96724.1 - 0.029 14.3 0.0 0.1 12.5 0.0 1.9 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea T2SSE PF00437.20 OQR96724.1 - 0.038 13.1 0.0 0.064 12.3 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein DAP3 PF10236.9 OQR96724.1 - 0.048 12.8 0.6 0.23 10.6 0.0 2.2 3 0 0 3 3 3 0 Mitochondrial ribosomal death-associated protein 3 AAA_18 PF13238.6 OQR96724.1 - 0.061 13.9 0.2 0.71 10.4 0.1 2.6 2 0 0 2 2 2 0 AAA domain AAA_21 PF13304.6 OQR96724.1 - 0.11 12.3 0.0 0.26 11.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_5 PF07728.14 OQR96724.1 - 0.13 12.2 0.2 1.1 9.3 0.0 2.4 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) Lar_restr_allev PF14354.6 OQR96724.1 - 0.18 12.2 0.1 0.44 11.0 0.1 1.6 1 0 0 1 1 1 0 Restriction alleviation protein Lar DUF3854 PF12965.7 OQR96724.1 - 0.18 11.8 0.0 0.56 10.2 0.0 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF3854) zf-CCHC_2 PF13696.6 OQR96724.1 - 0.56 10.1 3.8 0.35 10.7 0.3 2.2 2 0 0 2 2 2 0 Zinc knuckle Zn_Tnp_IS1595 PF12760.7 OQR96724.1 - 2.3 8.3 3.7 0.67 10.0 0.4 1.8 2 0 0 2 2 1 0 Transposase zinc-ribbon domain DUF4419 PF14388.6 OQR96725.1 - 2e-101 339.4 0.0 2.8e-101 338.9 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4419) Tetraspanin PF00335.20 OQR96725.1 - 7e-16 58.6 13.7 7e-16 58.6 13.7 2.8 4 0 0 4 4 4 1 Tetraspanin family CDP-OH_P_transf PF01066.21 OQR96725.1 - 3e-14 53.5 0.4 3e-14 53.5 0.4 4.7 5 1 0 5 5 5 1 CDP-alcohol phosphatidyltransferase PP2C PF00481.21 OQR96726.1 - 6.3e-48 163.6 0.1 8.1e-48 163.3 0.1 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 OQR96726.1 - 0.00055 19.6 0.3 0.0027 17.4 0.0 2.1 2 1 0 2 2 2 1 Protein phosphatase 2C SpoIIE PF07228.12 OQR96726.1 - 0.00058 19.8 0.1 0.22 11.4 0.0 2.2 2 0 0 2 2 2 2 Stage II sporulation protein E (SpoIIE) Ceramidase PF05875.12 OQR96727.1 - 1.1e-52 179.1 22.3 1.4e-52 178.8 22.3 1.1 1 0 0 1 1 1 1 Ceramidase C2 PF00168.30 OQR96728.1 - 1.5e-16 60.6 0.1 2.2e-08 34.3 0.0 2.3 2 0 0 2 2 2 2 C2 domain VHL PF01847.16 OQR96728.1 - 1.9e-15 56.5 0.2 7.1e-07 29.1 0.0 2.4 2 0 0 2 2 2 2 VHL beta domain DUF4497 PF14924.6 OQR96728.1 - 0.13 12.7 0.0 4 7.9 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4497) Glyco_hydro_20 PF00728.22 OQR96729.1 - 6.3e-91 305.4 0.3 7.9e-91 305.1 0.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.6 OQR96729.1 - 2.1e-11 44.6 1.6 6.7e-11 43.0 1.6 1.9 1 1 0 1 1 1 1 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.15 OQR96729.1 - 3.4e-05 24.6 0.1 0.00026 21.8 0.0 2.2 2 0 0 2 2 2 1 Glycosyl hydrolase family 20, domain 2 Chorismate_bind PF00425.18 OQR96730.1 - 1e-90 303.8 0.0 1.4e-90 303.3 0.0 1.2 1 0 0 1 1 1 1 chorismate binding enzyme GATase PF00117.28 OQR96730.1 - 2.4e-34 118.8 0.0 4.6e-34 117.8 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Anth_synt_I_N PF04715.13 OQR96730.1 - 8.3e-19 68.2 0.0 5.1e-18 65.7 0.0 2.1 2 0 0 2 2 2 1 Anthranilate synthase component I, N terminal region Peptidase_C26 PF07722.13 OQR96730.1 - 6.5e-11 42.4 0.0 1.4e-10 41.3 0.0 1.5 1 0 0 1 1 1 1 Peptidase C26 PAH PF02671.21 OQR96732.1 - 7.6e-42 141.2 10.2 1.4e-17 63.6 3.2 4.1 3 1 1 4 4 4 3 Paired amphipathic helix repeat Sin3_corepress PF08295.12 OQR96732.1 - 7.2e-36 122.2 0.0 2e-35 120.8 0.0 1.8 1 0 0 1 1 1 1 Sin3 family co-repressor Sin3a_C PF16879.5 OQR96732.1 - 1.9e-35 123.0 3.7 5e-35 121.6 0.1 2.9 3 0 0 3 3 3 1 C-terminal domain of Sin3a protein DUF1722 PF08349.11 OQR96732.1 - 0.53 10.6 6.2 17 5.7 0.0 4.1 5 0 0 5 5 5 0 Protein of unknown function (DUF1722) FHA PF00498.26 OQR96733.1 - 1.6e-13 50.8 0.2 1.3e-11 44.6 0.0 3.3 3 0 0 3 3 3 1 FHA domain RINGv PF12906.7 OQR96733.1 - 8.1e-13 48.3 5.4 2.3e-12 46.9 5.4 1.8 1 1 0 1 1 1 1 RING-variant domain Yop-YscD_cpl PF16697.5 OQR96733.1 - 2.4e-08 34.2 0.0 3.3e-07 30.5 0.0 2.5 2 0 0 2 2 2 1 Inner membrane component of T3SS, cytoplasmic domain zf-RING_2 PF13639.6 OQR96733.1 - 0.067 13.5 8.1 1.3 9.4 9.1 2.3 1 1 1 2 2 2 0 Ring finger domain MatE PF01554.18 OQR96735.1 - 2.9e-35 121.3 35.3 1.6e-18 66.8 15.8 2.4 2 0 0 2 2 2 2 MatE Pkinase PF00069.25 OQR96735.1 - 3.7e-24 85.5 0.1 8.8e-23 81.0 0.0 2.2 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQR96735.1 - 2.8e-23 82.5 0.1 7e-22 78.0 0.0 2.2 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase_Tyr PF07714.17 OQR96736.1 - 5.9e-06 25.8 0.0 8.7e-06 25.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OQR96736.1 - 0.00083 18.8 0.0 0.0083 15.5 0.0 2.3 3 0 0 3 3 3 1 Protein kinase domain Mid2 PF04478.12 OQR96736.1 - 0.0016 18.3 0.6 0.0031 17.4 0.6 1.4 1 0 0 1 1 1 1 Mid2 like cell wall stress sensor EphA2_TM PF14575.6 OQR96736.1 - 0.0074 17.1 0.0 0.015 16.2 0.0 1.5 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain EssA PF10661.9 OQR96736.1 - 0.0078 16.1 0.1 0.013 15.3 0.1 1.4 1 0 0 1 1 1 1 WXG100 protein secretion system (Wss), protein EssA Adeno_E3_CR2 PF02439.15 OQR96736.1 - 0.01 15.6 0.3 0.01 15.6 0.3 1.7 2 0 0 2 2 2 0 Adenovirus E3 region protein CR2 TMEM154 PF15102.6 OQR96736.1 - 0.055 13.4 0.1 0.099 12.6 0.1 1.4 1 0 0 1 1 1 0 TMEM154 protein family TMEM72 PF16054.5 OQR96736.1 - 0.09 12.5 0.0 0.34 10.6 0.0 1.8 2 0 0 2 2 2 0 Transmembrane protein family 72 Podoplanin PF05808.11 OQR96736.1 - 0.1 12.7 0.8 0.17 12.0 0.8 1.3 1 0 0 1 1 1 0 Podoplanin T4SS_CagC PF16943.5 OQR96736.1 - 0.14 12.3 0.8 0.61 10.3 0.4 2.0 1 1 1 2 2 2 0 Cag pathogenicity island, type IV secretory system Beta-APP PF03494.13 OQR96736.1 - 0.28 11.0 1.2 0.51 10.2 1.2 1.3 1 0 0 1 1 1 0 Beta-amyloid peptide (beta-APP) Pkinase_Tyr PF07714.17 OQR96737.1 - 4.8e-09 35.9 0.0 2.1e-07 30.5 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OQR96737.1 - 1.5e-06 27.8 0.0 6.2e-05 22.5 0.0 2.2 1 1 0 1 1 1 1 Protein kinase domain SKG6 PF08693.10 OQR96737.1 - 6.2e-06 25.5 2.6 1.3e-05 24.5 2.6 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Amnionless PF14828.6 OQR96737.1 - 0.00044 19.2 0.0 0.00056 18.9 0.0 1.1 1 0 0 1 1 1 1 Amnionless RIFIN PF02009.16 OQR96737.1 - 0.0046 16.9 0.8 0.0069 16.3 0.8 1.2 1 0 0 1 1 1 1 Rifin EphA2_TM PF14575.6 OQR96737.1 - 0.0064 17.4 0.0 0.011 16.6 0.0 1.4 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain TMEM154 PF15102.6 OQR96737.1 - 0.0071 16.3 2.4 0.0089 15.9 1.6 1.5 1 1 0 1 1 1 1 TMEM154 protein family Adeno_E3_CR2 PF02439.15 OQR96737.1 - 0.0095 15.7 1.2 0.019 14.7 1.2 1.4 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 SARAF PF06682.12 OQR96737.1 - 0.011 15.4 0.0 0.017 14.8 0.0 1.1 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis Mid2 PF04478.12 OQR96737.1 - 0.021 14.6 3.5 0.037 13.9 3.5 1.4 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor Protocadherin PF08374.11 OQR96737.1 - 0.024 14.6 0.0 0.032 14.2 0.0 1.2 1 0 0 1 1 1 0 Protocadherin Phage_Coat_B PF05356.11 OQR96737.1 - 0.028 14.3 1.1 0.048 13.6 1.1 1.3 1 0 0 1 1 1 0 Phage Coat protein B MGC-24 PF05283.11 OQR96737.1 - 0.036 14.5 1.5 0.071 13.6 1.5 1.5 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin DUF3827 PF12877.7 OQR96737.1 - 0.05 12.0 0.2 0.072 11.5 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) Tmemb_9 PF05434.11 OQR96737.1 - 0.06 13.2 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 TMEM9 Orf78 PF06024.12 OQR96737.1 - 0.063 13.6 0.0 0.13 12.5 0.0 1.5 1 0 0 1 1 1 0 Orf78 (ac78) DUF5305 PF17231.2 OQR96737.1 - 0.096 12.1 0.5 0.15 11.4 0.5 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5305) DUF4293 PF14126.6 OQR96737.1 - 0.15 12.3 0.6 0.26 11.5 0.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4293) Syndecan PF01034.20 OQR96737.1 - 0.18 11.7 4.0 0.34 10.8 4.0 1.4 1 0 0 1 1 1 0 Syndecan domain Stevor PF17410.2 OQR96737.1 - 0.33 10.5 0.7 0.46 10.0 0.7 1.2 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame DUF4519 PF15012.6 OQR96737.1 - 0.37 11.0 2.0 0.76 10.0 2.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4519) PsbX PF06596.11 OQR96737.1 - 1.6 8.8 8.5 3.7 7.6 8.5 1.5 1 0 0 1 1 1 0 Photosystem II reaction centre X protein (PsbX) FeoB_associated PF12669.7 OQR96737.1 - 9.6 6.7 6.2 63 4.1 0.0 2.5 2 0 0 2 2 2 0 FeoB-associated Cys-rich membrane protein Phage_holin_3_6 PF07332.11 OQR96787.1 - 0.017 15.2 3.7 0.022 14.8 3.7 1.2 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III Pkinase PF00069.25 OQR96788.1 - 1.2e-23 83.9 0.0 1.9e-23 83.2 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQR96788.1 - 4e-13 49.2 0.0 8.2e-13 48.2 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OQR96788.1 - 9.3e-06 24.7 2.7 0.00011 21.2 0.0 2.3 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 OQR96788.1 - 0.013 15.5 4.7 0.77 9.6 0.0 3.4 2 2 1 3 3 3 0 Phosphotransferase enzyme family Flu_NS1 PF00600.19 OQR96788.1 - 0.24 10.9 3.0 2 7.9 0.2 2.2 1 1 1 2 2 2 0 Influenza non-structural protein (NS1) DUF390 PF04094.14 OQR96788.1 - 2.2 6.5 18.3 3.1 6.0 18.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF390) TPR_2 PF07719.17 OQR96789.1 - 1.4e-31 106.0 15.4 6.6e-05 22.7 0.2 10.2 10 0 0 10 10 10 5 Tetratricopeptide repeat TPR_1 PF00515.28 OQR96789.1 - 9.1e-28 94.9 15.9 1.3e-05 24.8 0.0 9.5 10 0 0 10 10 10 4 Tetratricopeptide repeat TPR_8 PF13181.6 OQR96789.1 - 7.3e-23 78.8 3.9 6.1e-05 22.9 0.1 8.7 9 0 0 9 9 8 4 Tetratricopeptide repeat TPR_11 PF13414.6 OQR96789.1 - 2.3e-20 72.0 9.5 4.3e-08 32.7 0.0 6.7 5 2 2 7 7 6 4 TPR repeat TPR_17 PF13431.6 OQR96789.1 - 3.3e-16 58.4 5.5 0.00046 20.4 0.0 7.4 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_12 PF13424.6 OQR96789.1 - 5.3e-16 58.7 15.9 4.7e-09 36.4 0.0 7.7 7 2 1 8 8 8 2 Tetratricopeptide repeat TPR_14 PF13428.6 OQR96789.1 - 8.1e-16 57.4 8.5 0.066 14.1 0.1 10.1 6 2 5 11 11 10 5 Tetratricopeptide repeat ANAPC3 PF12895.7 OQR96789.1 - 1.7e-15 57.0 16.0 1.1e-07 31.9 0.0 6.8 6 1 1 7 7 7 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.6 OQR96789.1 - 2.5e-14 53.5 6.1 0.0051 17.3 0.1 7.5 7 1 1 8 8 8 4 Tetratricopeptide repeat TPR_16 PF13432.6 OQR96789.1 - 6.2e-14 52.4 9.2 3.5e-06 27.5 0.1 6.6 6 1 1 7 7 7 3 Tetratricopeptide repeat TPR_7 PF13176.6 OQR96789.1 - 4.7e-13 48.2 12.4 0.00033 20.5 0.0 8.0 10 0 0 10 10 10 3 Tetratricopeptide repeat TPR_9 PF13371.6 OQR96789.1 - 8.2e-10 38.7 0.1 0.00072 19.7 0.1 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_10 PF13374.6 OQR96789.1 - 4.9e-09 35.8 3.8 0.21 11.5 0.0 6.3 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_6 PF13174.6 OQR96789.1 - 5.2e-07 29.9 12.7 0.13 12.9 0.2 7.5 8 0 0 8 8 7 1 Tetratricopeptide repeat TPR_3 PF07720.12 OQR96789.1 - 1.2e-06 28.4 11.6 0.00042 20.2 0.1 6.2 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_4 PF07721.14 OQR96789.1 - 0.0015 18.9 0.7 6.2 7.8 0.0 5.0 5 0 0 5 5 3 1 Tetratricopeptide repeat TPR_MalT PF17874.1 OQR96789.1 - 0.0039 16.6 0.8 0.1 11.9 0.0 3.6 2 2 4 6 6 6 1 MalT-like TPR region MIT PF04212.18 OQR96789.1 - 0.013 15.6 0.8 85 3.3 0.0 4.8 4 0 0 4 4 4 0 MIT (microtubule interacting and transport) domain DiSB-ORF2_chro PF16506.5 OQR96789.1 - 0.082 12.9 0.0 0.6 10.2 0.0 2.4 2 0 0 2 2 2 0 Putative virion glycoprotein of insect viruses TPR_15 PF13429.6 OQR96789.1 - 0.1 11.8 3.0 24 4.0 0.0 4.5 4 2 1 5 5 5 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 OQR96789.1 - 0.16 12.0 5.2 3.3 7.8 0.1 4.7 6 0 0 6 6 5 0 Fis1 C-terminal tetratricopeptide repeat MutS_V PF00488.21 OQR96790.1 - 4e-57 193.3 0.1 6.9e-57 192.5 0.1 1.4 1 0 0 1 1 1 1 MutS domain V DENN PF02141.21 OQR96790.1 - 1.1e-18 67.9 2.5 4.1e-18 66.0 2.5 2.1 1 0 0 1 1 1 1 DENN (AEX-3) domain MutS_III PF05192.18 OQR96790.1 - 7.7e-18 65.4 0.6 2.2e-17 63.9 0.6 1.8 1 0 0 1 1 1 1 MutS domain III MutS_IV PF05190.18 OQR96790.1 - 6.7e-08 32.8 0.0 1.8e-07 31.4 0.0 1.7 1 0 0 1 1 1 1 MutS family domain IV RGS PF00615.19 OQR96790.1 - 7e-08 32.8 1.8 5.2e-06 26.7 0.1 3.9 3 0 0 3 3 3 1 Regulator of G protein signaling domain MutS_II PF05188.17 OQR96790.1 - 0.00021 21.6 0.2 0.0014 18.9 0.0 2.4 3 0 0 3 3 3 1 MutS domain II AAA_23 PF13476.6 OQR96790.1 - 0.12 12.9 1.2 0.79 10.2 0.5 2.5 2 0 0 2 2 2 0 AAA domain EF-hand_1 PF00036.32 OQR96791.1 - 1.8e-22 77.2 7.6 4.8e-07 28.9 1.0 3.6 3 0 0 3 3 3 3 EF hand EF-hand_7 PF13499.6 OQR96791.1 - 3.5e-19 69.0 4.0 1.3e-12 48.0 0.4 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 OQR96791.1 - 2.3e-16 58.2 6.4 7.7e-06 25.4 0.0 4.3 4 1 0 4 4 4 3 EF-hand domain EF-hand_8 PF13833.6 OQR96791.1 - 5.8e-14 51.7 5.5 6.8e-07 29.0 0.2 3.3 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.6 OQR96791.1 - 6.4e-13 47.6 6.3 0.00017 20.9 0.7 3.5 3 0 0 3 3 3 3 EF hand EF-hand_9 PF14658.6 OQR96791.1 - 2.4e-07 31.0 0.1 4.7e-05 23.6 0.0 2.2 2 0 0 2 2 2 1 EF-hand domain UPF0154 PF03672.13 OQR96791.1 - 0.067 13.2 0.0 0.11 12.6 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0154) SPARC_Ca_bdg PF10591.9 OQR96791.1 - 0.097 13.0 0.4 0.43 10.9 0.2 1.9 2 0 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region AAA PF00004.29 OQR96792.1 - 1.9e-37 128.6 0.0 1.6e-14 54.4 0.0 3.6 3 0 0 3 3 3 3 ATPase family associated with various cellular activities (AAA) AAA_12 PF13087.6 OQR96792.1 - 3.9e-28 98.5 0.0 1.1e-27 97.0 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 OQR96792.1 - 3.8e-14 53.1 4.3 6.7e-08 32.6 0.2 5.3 5 1 0 5 5 5 2 AAA domain AAA_5 PF07728.14 OQR96792.1 - 6.6e-13 48.9 0.2 3.3e-05 23.9 0.1 3.8 3 0 0 3 3 3 3 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 OQR96792.1 - 7.6e-13 48.9 6.7 0.15 12.3 0.0 7.4 4 3 1 5 5 4 4 AAA domain AAA_lid_6 PF17866.1 OQR96792.1 - 1.8e-11 44.0 0.1 1.6e-05 25.0 0.1 2.8 2 0 0 2 2 2 2 AAA lid domain AAA_30 PF13604.6 OQR96792.1 - 1.6e-08 34.5 0.0 0.11 12.2 0.0 4.3 4 0 0 4 4 4 3 AAA domain Sigma54_activat PF00158.26 OQR96792.1 - 3e-08 33.6 1.7 0.12 12.1 0.2 5.1 3 3 0 3 3 3 2 Sigma-54 interaction domain RuvB_N PF05496.12 OQR96792.1 - 4.2e-08 33.1 0.0 0.0067 16.2 0.0 3.6 3 0 0 3 3 3 1 Holliday junction DNA helicase RuvB P-loop domain Mg_chelatase PF01078.21 OQR96792.1 - 4.8e-08 32.6 0.7 0.074 12.4 0.0 5.3 3 2 2 5 5 5 1 Magnesium chelatase, subunit ChlI AAA_18 PF13238.6 OQR96792.1 - 5.3e-08 33.5 1.0 0.19 12.3 0.0 4.4 4 0 0 4 4 3 2 AAA domain AAA_16 PF13191.6 OQR96792.1 - 2e-07 31.5 5.9 0.1 13.0 0.1 5.0 2 2 1 3 3 3 2 AAA ATPase domain Torsin PF06309.11 OQR96792.1 - 3.4e-07 30.4 0.0 0.0015 18.7 0.0 3.1 2 0 0 2 2 2 2 Torsin AAA_33 PF13671.6 OQR96792.1 - 5.1e-07 29.9 0.0 0.19 11.9 0.0 4.0 4 0 0 4 4 3 1 AAA domain AAA_2 PF07724.14 OQR96792.1 - 1.1e-06 28.9 0.0 0.012 15.7 0.0 3.1 3 0 0 3 3 3 2 AAA domain (Cdc48 subfamily) ResIII PF04851.15 OQR96792.1 - 5e-06 26.6 0.2 0.0054 16.8 0.0 4.4 3 1 1 4 4 4 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 OQR96792.1 - 7.9e-06 26.3 1.1 2 8.7 0.0 5.4 4 2 2 6 6 6 1 AAA domain Sigma54_activ_2 PF14532.6 OQR96792.1 - 1.1e-05 25.5 0.0 0.36 10.9 0.0 4.1 3 0 0 3 3 3 1 Sigma-54 interaction domain AAA_24 PF13479.6 OQR96792.1 - 4.1e-05 23.4 0.1 0.87 9.3 0.0 3.6 3 0 0 3 3 3 1 AAA domain RNA_helicase PF00910.22 OQR96792.1 - 4.3e-05 23.9 0.1 5.2 7.5 0.0 4.0 3 0 0 3 3 3 0 RNA helicase AAA_7 PF12775.7 OQR96792.1 - 6.3e-05 22.6 0.3 8.1 5.9 0.0 4.1 4 0 0 4 4 4 0 P-loop containing dynein motor region IstB_IS21 PF01695.17 OQR96792.1 - 0.0001 22.1 0.0 0.7 9.6 0.0 3.6 3 0 0 3 3 3 1 IstB-like ATP binding protein AAA_17 PF13207.6 OQR96792.1 - 0.00013 22.4 0.8 0.12 12.7 0.0 3.7 3 0 0 3 3 3 1 AAA domain ABC_tran PF00005.27 OQR96792.1 - 0.00023 21.7 0.0 18 5.8 0.0 4.3 3 0 0 3 3 3 0 ABC transporter AAA_28 PF13521.6 OQR96792.1 - 0.00047 20.4 1.2 1.9 8.7 0.0 4.0 4 0 0 4 4 3 1 AAA domain zf-primase PF09329.11 OQR96792.1 - 0.00096 18.9 2.0 0.00096 18.9 2.0 5.0 4 0 0 4 4 4 1 Primase zinc finger TsaE PF02367.17 OQR96792.1 - 0.0025 17.8 0.9 4 7.5 0.0 3.9 5 0 0 5 5 3 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_3 PF07726.11 OQR96792.1 - 0.011 15.6 0.0 2 8.3 0.0 3.1 3 0 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) DUF3987 PF13148.6 OQR96792.1 - 0.014 14.5 5.1 2.5 7.0 0.0 4.6 5 0 0 5 5 5 0 Protein of unknown function (DUF3987) PRK PF00485.18 OQR96792.1 - 0.015 15.1 0.1 7.1 6.3 0.0 2.7 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family MobB PF03205.14 OQR96792.1 - 0.035 14.0 0.2 0.32 10.9 0.0 2.8 4 0 0 4 4 2 0 Molybdopterin guanine dinucleotide synthesis protein B SKI PF01202.22 OQR96792.1 - 0.041 14.0 1.9 7.6 6.6 0.0 2.9 3 0 0 3 3 2 0 Shikimate kinase NACHT PF05729.12 OQR96792.1 - 0.05 13.5 0.4 9.6 6.1 0.0 3.4 3 0 0 3 3 3 0 NACHT domain PhoH PF02562.16 OQR96792.1 - 0.059 12.8 0.4 15 5.0 0.0 3.1 3 0 0 3 3 3 0 PhoH-like protein NTPase_1 PF03266.15 OQR96792.1 - 0.062 13.2 0.5 46 3.9 0.0 3.5 3 0 0 3 3 3 0 NTPase CbiA PF01656.23 OQR96792.1 - 0.068 13.2 0.4 19 5.3 0.0 3.1 3 0 0 3 3 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain DUF2075 PF09848.9 OQR96792.1 - 0.13 11.5 5.6 41 3.3 0.0 4.6 4 1 0 4 4 4 0 Uncharacterized conserved protein (DUF2075) APS_kinase PF01583.20 OQR96792.1 - 0.14 12.1 0.2 23 4.9 0.0 2.9 3 0 0 3 3 2 0 Adenylylsulphate kinase IFT81_CH PF18383.1 OQR96792.1 - 0.15 12.3 0.7 2.1 8.6 0.1 2.8 2 0 0 2 2 2 0 Intraflagellar transport 81 calponin homology domain ATPase PF06745.13 OQR96792.1 - 0.18 11.1 0.2 8.5 5.7 0.0 3.1 3 0 0 3 3 3 0 KaiC SRP54 PF00448.22 OQR96792.1 - 0.19 11.3 1.5 32 4.1 0.0 3.3 3 0 0 3 3 3 0 SRP54-type protein, GTPase domain AAA_15 PF13175.6 OQR96792.1 - 3.5 7.3 5.5 0.88 9.2 0.5 2.3 2 0 0 2 2 2 0 AAA ATPase domain Ank_5 PF13857.6 OQR96806.1 - 6.4e-07 29.5 0.5 0.00058 20.1 0.1 2.5 2 1 0 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 OQR96806.1 - 4.9e-05 23.8 0.2 0.00019 22.0 0.1 1.7 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQR96806.1 - 0.00016 22.1 0.3 0.075 13.6 0.0 2.8 1 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQR96806.1 - 0.017 15.6 0.2 4.1 8.3 0.0 3.6 3 1 1 4 4 4 0 Ankyrin repeat DUF3802 PF12290.8 OQR96806.1 - 0.018 15.5 0.1 0.57 10.7 0.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3802) DUF5049 PF16468.5 OQR96806.1 - 0.042 13.8 0.0 7.2 6.6 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF5049) CLU PF13236.6 OQR96807.1 - 8.9e-32 110.7 0.0 2.5e-31 109.2 0.0 1.7 1 0 0 1 1 1 1 Clustered mitochondria Jacalin PF01419.17 OQR96807.1 - 1.1e-13 51.3 0.1 8e-06 25.8 0.0 3.3 3 0 0 3 3 3 2 Jacalin-like lectin domain Metallopep PF12044.8 OQR96807.1 - 2e-08 33.3 0.0 0.0016 17.2 0.0 2.8 3 0 0 3 3 3 2 Putative peptidase family eIF3_p135 PF12807.7 OQR96807.1 - 2.8e-06 27.5 0.1 1.1e-05 25.6 0.1 2.0 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit 135 Ank_2 PF12796.7 OQR96810.1 - 9.7e-08 32.5 6.1 0.00023 21.7 0.5 1.7 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQR96810.1 - 0.00015 22.2 0.1 0.00047 20.7 0.1 1.8 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQR96810.1 - 0.0021 18.4 0.5 4.3 8.2 0.1 2.9 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.6 OQR96810.1 - 0.0048 17.2 0.3 0.011 16.0 0.3 1.6 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.30 OQR96810.1 - 0.0071 16.7 2.0 0.52 10.9 0.3 2.8 2 0 0 2 2 2 1 Ankyrin repeat VWA_2 PF13519.6 OQR96810.1 - 0.13 12.9 0.0 0.4 11.3 0.0 1.8 2 0 0 2 2 2 0 von Willebrand factor type A domain Alpha_kinase PF02816.18 OQR96811.1 - 3.2e-24 86.1 0.5 3.9e-24 85.8 0.5 1.1 1 0 0 1 1 1 1 Alpha-kinase family Stanniocalcin PF03298.13 OQR96811.1 - 0.063 12.6 0.0 0.083 12.2 0.0 1.3 1 0 0 1 1 1 0 Stanniocalcin family Glutaredoxin PF00462.24 OQR96812.1 - 9.6e-48 160.2 0.0 5.9e-15 55.2 0.0 3.5 3 0 0 3 3 3 3 Glutaredoxin EAP30 PF04157.16 OQR96812.1 - 2.1e-37 128.7 1.7 5.9e-37 127.2 1.1 1.9 2 0 0 2 2 2 1 EAP30/Vps36 family Vps36_ESCRT-II PF11605.8 OQR96812.1 - 7.9e-14 51.6 0.0 1.4e-13 50.8 0.0 1.4 1 0 0 1 1 1 1 Vacuolar protein sorting protein 36 Vps36 Ricin_B_lectin PF00652.22 OQR96812.1 - 6.3e-05 23.2 0.8 0.00012 22.3 0.8 1.4 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain SH3BGR PF04908.15 OQR96812.1 - 0.0049 17.0 0.0 5.6 7.2 0.0 3.6 3 0 0 3 3 3 1 SH3-binding, glutamic acid-rich protein Thioredoxin PF00085.20 OQR96812.1 - 0.0077 16.2 0.0 0.025 14.6 0.0 1.9 1 1 0 1 1 1 1 Thioredoxin HTH_24 PF13412.6 OQR96812.1 - 0.15 11.7 0.0 0.48 10.0 0.0 2.0 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding RdRP PF05183.12 OQR96812.1 - 0.16 10.6 0.0 11 4.6 0.0 2.6 1 1 1 3 3 3 0 RNA dependent RNA polymerase Peptidase_C97 PF05903.14 OQR96821.1 - 3.5e-31 108.1 0.0 4.6e-31 107.7 0.0 1.1 1 0 0 1 1 1 1 PPPDE putative peptidase domain DUF778 PF05608.12 OQR96821.1 - 0.016 15.6 0.2 0.03 14.7 0.1 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF778) LRAT PF04970.13 OQR96821.1 - 0.1 12.9 0.0 0.16 12.3 0.0 1.4 1 0 0 1 1 1 0 Lecithin retinol acyltransferase GGACT PF06094.12 OQR96822.1 - 2.4e-19 70.1 0.2 2.9e-19 69.8 0.2 1.0 1 0 0 1 1 1 1 Gamma-glutamyl cyclotransferase, AIG2-like AAA_8 PF12780.7 OQR96823.1 - 7.8e-102 340.0 0.3 2e-101 338.7 0.0 1.9 2 0 0 2 2 2 1 P-loop containing dynein motor region D4 Dynein_C PF18199.1 OQR96823.1 - 3.6e-101 338.4 0.0 9.2e-101 337.1 0.0 1.8 1 0 0 1 1 1 1 Dynein heavy chain C-terminal domain AAA_9 PF12781.7 OQR96823.1 - 4.9e-82 274.3 5.3 4.1e-81 271.3 0.1 3.5 4 0 0 4 4 4 1 ATP-binding dynein motor region AAA_7 PF12775.7 OQR96823.1 - 2.7e-77 258.4 0.0 6.4e-77 257.2 0.0 1.7 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_lid_11 PF18198.1 OQR96823.1 - 3.3e-53 179.9 0.1 9.2e-53 178.4 0.1 1.8 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 OQR96823.1 - 3.5e-49 165.8 0.0 3.8e-44 149.6 0.0 3.0 2 0 0 2 2 2 2 Dynein heavy chain region D6 P-loop domain MT PF12777.7 OQR96823.1 - 1.6e-39 135.9 12.1 1.6e-39 135.9 12.1 1.7 2 0 0 2 2 2 1 Microtubule-binding stalk of dynein motor Dynein_AAA_lid PF17852.1 OQR96823.1 - 3.6e-30 104.7 0.4 2.1e-29 102.2 0.4 2.5 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_lid_1 PF17857.1 OQR96823.1 - 8.8e-16 58.0 1.0 3.5e-15 56.0 0.2 2.5 2 0 0 2 2 1 1 AAA+ lid domain AAA_5 PF07728.14 OQR96823.1 - 1.4e-10 41.3 0.0 2.7e-05 24.2 0.0 3.9 3 0 0 3 3 3 2 AAA domain (dynein-related subfamily) T2SSE PF00437.20 OQR96823.1 - 0.00042 19.4 0.0 0.0047 16.0 0.0 2.2 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_16 PF13191.6 OQR96823.1 - 0.0027 18.1 0.0 0.27 11.6 0.0 3.2 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 OQR96823.1 - 0.005 17.1 1.4 0.05 13.9 0.0 2.9 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 OQR96823.1 - 0.045 14.2 0.0 0.29 11.6 0.0 2.3 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) PhoLip_ATPase_N PF16209.5 OQR96823.1 - 0.32 10.7 1.6 14 5.5 0.1 2.7 2 0 0 2 2 2 0 Phospholipid-translocating ATPase N-terminal GAS PF13851.6 OQR96823.1 - 0.41 10.0 15.9 1.1 8.6 0.4 3.1 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding DUF3584 PF12128.8 OQR96823.1 - 0.42 8.1 11.0 1.1 6.7 6.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) TSNAXIP1_N PF15739.5 OQR96823.1 - 6 7.3 10.2 0.92 9.9 3.9 2.8 2 0 0 2 2 2 0 Translin-associated factor X-interacting N-terminus Sigma70_r1_1 PF03979.14 OQR96823.1 - 6.5 6.9 11.9 18 5.5 3.6 3.4 3 0 0 3 3 3 0 Sigma-70 factor, region 1.1 p450 PF00067.22 OQR96824.1 - 5.3e-68 229.9 0.0 6.4e-68 229.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 PUL PF08324.11 OQR96824.1 - 0.039 13.2 0.1 0.062 12.5 0.1 1.2 1 0 0 1 1 1 0 PUL domain NinF PF05810.12 OQR96824.1 - 0.16 11.9 0.0 0.32 10.9 0.0 1.4 1 0 0 1 1 1 0 NinF protein Evr1_Alr PF04777.13 OQR96825.1 - 0.08 13.4 0.7 0.84 10.1 0.0 2.3 1 1 1 2 2 2 0 Erv1 / Alr family Nup192 PF11894.8 OQR96826.1 - 1.1e-82 278.1 5.6 1.1e-82 278.1 5.6 2.6 2 1 0 2 2 2 1 Nuclear pore complex scaffold, nucleoporins 186/192/205 Cation_ATPase_C PF00689.21 OQR96827.1 - 6e-47 159.7 4.3 9.2e-47 159.1 4.3 1.3 1 0 0 1 1 1 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 OQR96827.1 - 1.1e-10 42.2 0.1 6.7e-10 39.6 0.1 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase ATP_Ca_trans_C PF12424.8 OQR96827.1 - 8.9e-10 38.9 0.4 2.6e-09 37.4 0.4 1.8 1 0 0 1 1 1 1 Plasma membrane calcium transporter ATPase C terminal Hydrolase_3 PF08282.12 OQR96827.1 - 2.1e-05 24.4 1.6 0.0022 17.8 0.4 2.2 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase TRM13 PF05206.14 OQR96828.1 - 2e-68 230.8 1.5 1.7e-67 227.7 0.1 2.4 2 1 0 2 2 2 1 Methyltransferase TRM13 zf-TRM13_CCCH PF11722.8 OQR96828.1 - 6.6e-10 38.6 1.2 6.6e-10 38.6 1.2 2.3 2 0 0 2 2 2 1 CCCH zinc finger in TRM13 protein zf-U11-48K PF05253.12 OQR96828.1 - 5.1e-05 23.1 0.4 0.0001 22.1 0.4 1.5 1 0 0 1 1 1 1 U11-48K-like CHHC zinc finger DUF3730 PF12530.8 OQR96829.1 - 1.3e-10 41.2 6.6 1.3e-10 41.2 6.6 4.0 2 1 1 3 3 3 1 Protein of unknown function (DUF3730) Opiods_neuropep PF01160.18 OQR96829.1 - 0.093 12.8 0.4 1.3 9.1 0.0 2.9 2 0 0 2 2 2 0 Vertebrate endogenous opioids neuropeptide Peptidase_C58 PF03543.14 OQR96829.1 - 0.11 12.2 0.3 0.33 10.6 0.3 1.8 1 0 0 1 1 1 0 Yersinia/Haemophilus virulence surface antigen RICTOR_V PF14668.6 OQR96829.1 - 0.14 12.4 2.3 57 4.1 0.0 4.3 3 0 0 3 3 3 0 Rapamycin-insensitive companion of mTOR, domain 5 HEAT PF02985.22 OQR96829.1 - 0.33 11.3 8.1 3.4 8.2 0.0 5.1 5 0 0 5 5 5 0 HEAT repeat MMR_HSR1_C PF08438.10 OQR96830.1 - 3.9e-33 114.4 0.0 6.4e-33 113.7 0.0 1.4 1 0 0 1 1 1 1 GTPase of unknown function C-terminal MMR_HSR1 PF01926.23 OQR96830.1 - 1.2e-20 73.7 0.0 4.8e-20 71.7 0.0 1.9 1 1 1 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 OQR96830.1 - 8.9e-10 38.3 0.2 1e-08 34.9 0.1 2.3 2 0 0 2 2 2 1 Ferrous iron transport protein B TGS PF02824.21 OQR96830.1 - 0.00058 19.9 0.0 0.0012 18.9 0.0 1.5 1 0 0 1 1 1 1 TGS domain RsgA_GTPase PF03193.16 OQR96830.1 - 0.13 12.1 0.1 3.4 7.6 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase ABC_tran PF00005.27 OQR96831.1 - 2.7e-25 89.5 0.0 4.8e-25 88.7 0.0 1.4 1 0 0 1 1 1 1 ABC transporter ABC2_membrane_3 PF12698.7 OQR96831.1 - 3.5e-13 49.4 30.4 6.3e-13 48.6 20.3 2.7 2 1 0 2 2 2 2 ABC-2 family transporter protein AAA_21 PF13304.6 OQR96831.1 - 4e-11 43.3 0.4 1.2e-07 31.8 0.1 2.3 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system GlcNAc PF11397.8 OQR96832.1 - 1.5e-56 192.3 1.3 5.7e-51 174.0 0.3 2.1 1 1 1 2 2 2 2 Glycosyltransferase (GlcNAc) Av_adeno_fibre PF06536.11 OQR96832.1 - 0.041 13.7 0.0 0.077 12.9 0.0 1.4 1 0 0 1 1 1 0 Avian adenovirus fibre, N-terminal LapA_dom PF06305.11 OQR96832.1 - 0.11 12.3 0.2 0.2 11.5 0.2 1.4 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain Internalin_N PF12354.8 OQR96832.1 - 0.63 10.2 3.9 19 5.4 0.0 3.0 3 0 0 3 3 3 0 Bacterial adhesion/invasion protein N terminal Utp8 PF10395.9 OQR96833.1 - 2.9e-09 36.0 1.7 5.8e-09 35.0 1.7 1.4 1 0 0 1 1 1 1 Utp8 family Utp12 PF04003.12 OQR96833.1 - 1e-06 29.0 0.3 2.5e-06 27.8 0.3 1.7 1 0 0 1 1 1 1 Dip2/Utp12 Family Y_phosphatase2 PF03162.13 OQR96833.1 - 0.088 12.4 0.1 0.2 11.2 0.1 1.6 1 0 0 1 1 1 0 Tyrosine phosphatase family GRDP-like PF07173.12 OQR96863.1 - 4.4e-05 24.2 0.7 0.00016 22.4 0.8 1.9 1 1 0 1 1 1 1 Glycine-rich domain-containing protein-like IBR PF01485.21 OQR96864.1 - 0.67 10.2 7.0 0.4 11.0 3.9 1.9 1 1 1 2 2 2 0 IBR domain, a half RING-finger domain Pyr_redox_2 PF07992.14 OQR96865.1 - 4.5e-36 124.6 0.6 1.8e-35 122.6 0.6 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 OQR96865.1 - 2.1e-19 69.9 0.4 1e-11 45.2 0.1 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 OQR96865.1 - 4e-08 32.9 0.6 8.5e-07 28.5 0.2 2.0 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.6 OQR96865.1 - 0.00011 22.5 0.5 0.27 11.7 0.1 2.5 2 0 0 2 2 2 2 Putative NAD(P)-binding K_oxygenase PF13434.6 OQR96865.1 - 0.00029 20.1 1.3 0.0063 15.7 0.1 2.5 2 1 1 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Lycopene_cycl PF05834.12 OQR96865.1 - 0.00034 19.8 0.0 0.0064 15.6 0.0 2.2 2 0 0 2 2 2 1 Lycopene cyclase protein ThiF PF00899.21 OQR96865.1 - 0.011 15.2 0.6 0.03 13.7 0.0 2.0 3 0 0 3 3 3 0 ThiF family NAD_binding_8 PF13450.6 OQR96865.1 - 0.013 15.7 0.0 5.6 7.3 0.0 3.1 3 0 0 3 3 3 0 NAD(P)-binding Rossmann-like domain DAO PF01266.24 OQR96865.1 - 0.014 15.0 4.0 0.21 11.1 0.6 3.1 2 2 1 4 4 4 0 FAD dependent oxidoreductase ApbA PF02558.16 OQR96865.1 - 0.027 14.1 0.5 0.81 9.3 0.1 2.3 1 1 1 2 2 2 0 Ketopantoate reductase PanE/ApbA GIDA PF01134.22 OQR96865.1 - 0.037 13.1 1.7 0.41 9.7 0.2 2.5 2 1 0 2 2 2 0 Glucose inhibited division protein A TrkA_N PF02254.18 OQR96865.1 - 0.046 14.0 2.5 0.61 10.4 0.1 3.1 3 0 0 3 3 3 0 TrkA-N domain Frankia_peptide PF14407.6 OQR96865.1 - 0.16 12.0 0.0 0.71 9.9 0.0 2.0 2 0 0 2 2 2 0 Ribosomally synthesized peptide prototyped by Frankia Franean1_4349. HI0933_like PF03486.14 OQR96865.1 - 1.1 7.9 2.9 6.3 5.4 0.3 2.9 3 1 1 4 4 4 0 HI0933-like protein SPX PF03105.19 OQR96866.1 - 1.5e-18 67.9 25.7 3.1e-11 43.8 0.4 3.6 2 1 2 4 4 4 3 SPX domain CLAMP PF14769.6 OQR96866.1 - 0.06 13.8 0.2 0.06 13.8 0.2 2.4 4 0 0 4 4 4 0 Flagellar C1a complex subunit C1a-32 DUF4306 PF14154.6 OQR96866.1 - 0.19 11.9 1.5 10 6.3 0.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4306) PAP2_C PF14360.6 OQR96867.1 - 1.3e-38 131.3 30.1 3.7e-20 72.2 8.9 3.3 3 0 0 3 3 3 2 PAP2 superfamily C-terminal PAP2_3 PF14378.6 OQR96867.1 - 2.1e-12 47.1 20.5 4.5e-06 26.5 5.3 2.5 2 0 0 2 2 2 2 PAP2 superfamily PAP2 PF01569.21 OQR96867.1 - 5.4e-06 26.2 16.2 0.0066 16.2 4.3 2.8 2 1 0 2 2 2 2 PAP2 superfamily TMEM18 PF14770.6 OQR96867.1 - 3 7.8 10.8 8.4 6.4 1.0 3.1 2 0 0 2 2 2 0 Transmembrane protein 18 AARP2CN PF08142.12 OQR96869.1 - 7.1e-29 99.7 0.0 2.9e-28 97.8 0.0 2.1 1 0 0 1 1 1 1 AARP2CN (NUC121) domain GTP_EFTU PF00009.27 OQR96869.1 - 3.8e-06 26.6 0.0 0.0031 17.1 0.0 2.4 1 1 1 2 2 2 2 Elongation factor Tu GTP binding domain PduV-EutP PF10662.9 OQR96869.1 - 1.9e-05 24.4 1.2 0.00062 19.5 0.0 2.7 2 1 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation AAA_22 PF13401.6 OQR96869.1 - 2.2e-05 24.7 0.0 4.9e-05 23.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 OQR96869.1 - 4.5e-05 23.9 0.0 9.9e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain ABC_tran PF00005.27 OQR96869.1 - 0.00034 21.1 0.1 0.0015 19.1 0.1 1.9 1 1 0 1 1 1 1 ABC transporter MMR_HSR1 PF01926.23 OQR96869.1 - 0.00048 20.2 1.9 0.0012 18.9 0.1 2.5 2 1 0 2 2 1 1 50S ribosome-binding GTPase AAA_33 PF13671.6 OQR96869.1 - 0.00053 20.2 0.0 0.0016 18.6 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA PF00004.29 OQR96869.1 - 0.00072 20.0 0.0 0.0017 18.8 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 OQR96869.1 - 0.0012 19.4 1.2 0.0025 18.4 0.0 2.2 2 0 0 2 2 1 1 AAA domain RNA_helicase PF00910.22 OQR96869.1 - 0.0025 18.2 0.0 0.03 14.7 0.0 2.6 2 0 0 2 2 2 1 RNA helicase cobW PF02492.19 OQR96869.1 - 0.0039 16.8 0.0 0.0078 15.8 0.0 1.4 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain Viral_helicase1 PF01443.18 OQR96869.1 - 0.0043 16.8 0.1 0.0088 15.8 0.1 1.5 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase RsgA_GTPase PF03193.16 OQR96869.1 - 0.0068 16.3 0.1 0.019 14.9 0.0 1.8 1 1 0 1 1 1 1 RsgA GTPase AAA_28 PF13521.6 OQR96869.1 - 0.0081 16.4 0.0 0.015 15.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 OQR96869.1 - 0.011 15.0 0.0 0.033 13.5 0.0 1.7 1 1 1 2 2 2 0 Zeta toxin Ploopntkinase3 PF18751.1 OQR96869.1 - 0.013 15.4 0.0 0.032 14.1 0.0 1.6 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 AAA_30 PF13604.6 OQR96869.1 - 0.013 15.2 0.0 0.024 14.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 OQR96869.1 - 0.013 15.4 0.0 0.023 14.6 0.0 1.5 1 0 0 1 1 1 0 NACHT domain ATPase_2 PF01637.18 OQR96869.1 - 0.013 15.4 0.0 0.038 13.9 0.0 1.8 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_24 PF13479.6 OQR96869.1 - 0.028 14.1 0.0 0.1 12.3 0.0 1.9 2 0 0 2 2 1 0 AAA domain AAA_19 PF13245.6 OQR96869.1 - 0.03 14.6 0.1 0.076 13.4 0.1 1.6 1 0 0 1 1 1 0 AAA domain ATP_bind_1 PF03029.17 OQR96869.1 - 0.037 13.8 0.0 0.075 12.8 0.0 1.5 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein AAA_29 PF13555.6 OQR96869.1 - 0.038 13.7 0.0 0.084 12.6 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain NTPase_1 PF03266.15 OQR96869.1 - 0.041 13.8 0.2 0.091 12.7 0.2 1.6 1 0 0 1 1 1 0 NTPase Adeno_IVa2 PF02456.15 OQR96869.1 - 0.042 12.6 0.0 0.066 12.0 0.0 1.2 1 0 0 1 1 1 0 Adenovirus IVa2 protein AAA_5 PF07728.14 OQR96869.1 - 0.045 13.8 0.0 0.091 12.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_17 PF13207.6 OQR96869.1 - 0.054 13.9 1.4 0.072 13.5 0.1 2.0 2 0 0 2 2 1 0 AAA domain KAP_NTPase PF07693.14 OQR96869.1 - 0.054 12.7 0.0 0.15 11.3 0.0 1.6 1 1 0 1 1 1 0 KAP family P-loop domain DUF815 PF05673.13 OQR96869.1 - 0.086 12.0 0.0 0.12 11.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) FtsK_SpoIIIE PF01580.18 OQR96869.1 - 0.17 11.2 0.0 0.51 9.7 0.0 1.7 2 0 0 2 2 2 0 FtsK/SpoIIIE family RNA12 PF10443.9 OQR96869.1 - 0.72 8.5 0.0 0.72 8.5 0.0 2.9 3 0 0 3 3 3 0 RNA12 protein DNA_pol_phi PF04931.13 OQR96869.1 - 1.7 6.6 20.4 3.6 5.6 20.4 1.4 1 0 0 1 1 1 0 DNA polymerase phi Motile_Sperm PF00635.26 OQR96870.1 - 9.3e-20 70.5 0.2 1.2e-17 63.7 0.1 2.9 3 0 0 3 3 3 1 MSP (Major sperm protein) domain Seryl_tRNA_N PF02403.22 OQR96870.1 - 0.028 14.6 2.0 0.06 13.6 2.0 1.5 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain DUF4484 PF14831.6 OQR96870.1 - 0.04 14.0 2.1 0.067 13.2 1.5 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4484) DUF4662 PF15578.6 OQR96870.1 - 0.08 12.7 2.8 0.11 12.3 2.3 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4662) Ax_dynein_light PF10211.9 OQR96870.1 - 0.087 12.8 3.6 0.15 12.0 3.6 1.3 1 0 0 1 1 1 0 Axonemal dynein light chain RasGAP_C PF03836.15 OQR96870.1 - 0.12 12.5 3.8 0.23 11.6 3.8 1.4 1 0 0 1 1 1 0 RasGAP C-terminus HALZ PF02183.18 OQR96870.1 - 0.66 10.2 4.8 1.3 9.3 1.6 2.4 1 1 1 2 2 2 0 Homeobox associated leucine zipper DivIC PF04977.15 OQR96870.1 - 2.7 7.8 5.5 4.6 7.1 4.0 2.1 1 1 1 2 2 2 0 Septum formation initiator UPF0203 PF05254.12 OQR96887.1 - 0.016 15.5 2.7 0.11 12.7 2.7 2.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0203) DUF4141 PF13605.6 OQR96887.1 - 0.19 11.0 0.9 0.42 9.9 0.9 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4141) Innexin PF00876.18 OQR96888.1 - 0.083 12.2 0.0 0.094 12.0 0.0 1.1 1 0 0 1 1 1 0 Innexin Adeno_E3_14_5 PF04834.12 OQR96888.1 - 0.17 12.4 0.9 0.33 11.5 0.9 1.5 1 1 1 2 2 2 0 Early E3 14.5 kDa protein MotA_ExbB PF01618.16 OQR96888.1 - 0.24 11.2 3.0 2 8.2 3.0 2.1 1 1 0 1 1 1 0 MotA/TolQ/ExbB proton channel family PhyH PF05721.13 OQR96889.1 - 1.4e-06 28.7 0.7 1.5e-05 25.4 0.7 2.2 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) 2OG-FeII_Oxy_5 PF13759.6 OQR96889.1 - 0.015 15.7 0.3 0.039 14.4 0.3 1.6 1 0 0 1 1 1 0 Putative 2OG-Fe(II) oxygenase 2OG-FeII_Oxy_3 PF13640.6 OQR96889.1 - 0.023 15.6 0.1 0.046 14.6 0.1 1.5 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily Strep_his_triad PF04270.13 OQR96889.1 - 0.12 12.4 0.6 1.1 9.3 0.1 2.3 2 0 0 2 2 2 0 Streptococcal histidine triad protein EF-hand_1 PF00036.32 OQR96890.1 - 5.4e-32 106.9 17.8 2.6e-06 26.6 0.8 8.9 8 0 0 8 8 8 7 EF hand EF-hand_7 PF13499.6 OQR96890.1 - 2.4e-30 104.8 20.0 1.1e-08 35.4 1.2 5.6 3 2 3 6 6 6 6 EF-hand domain pair EF-hand_5 PF13202.6 OQR96890.1 - 5.3e-25 85.8 16.0 3.8e-05 23.0 0.6 8.6 8 0 0 8 8 8 5 EF hand EF-hand_6 PF13405.6 OQR96890.1 - 1.1e-24 84.2 21.0 0.00095 18.9 0.5 8.9 9 0 0 9 9 9 8 EF-hand domain EF-hand_8 PF13833.6 OQR96890.1 - 3.9e-23 81.1 18.1 2e-09 37.1 1.8 7.0 6 2 2 8 8 8 3 EF-hand domain pair HU-CCDC81_euk_2 PF18289.1 OQR96890.1 - 0.00071 19.7 0.0 0.0017 18.5 0.0 1.6 1 0 0 1 1 1 1 CCDC81 eukaryotic HU domain 2 EF-hand_9 PF14658.6 OQR96890.1 - 0.0014 18.9 7.1 1.6 9.1 0.0 5.2 4 2 0 4 4 4 1 EF-hand domain Dockerin_1 PF00404.18 OQR96890.1 - 0.0021 18.2 7.8 6.7 7.0 0.0 5.8 5 1 0 5 5 5 2 Dockerin type I domain IQ PF00612.27 OQR96890.1 - 0.043 13.6 0.5 0.043 13.6 0.5 2.2 2 0 0 2 2 1 0 IQ calmodulin-binding motif Caleosin PF05042.13 OQR96890.1 - 2.4 8.1 10.0 24 4.8 0.0 5.4 5 2 1 6 6 6 0 Caleosin related protein EF-hand_4 PF12763.7 OQR96890.1 - 7.6 6.5 8.3 9.4 6.3 0.2 3.7 4 1 0 4 4 4 0 Cytoskeletal-regulatory complex EF hand Ank_2 PF12796.7 OQR96891.1 - 2.1e-15 57.0 0.3 0.0004 20.9 0.0 3.6 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQR96891.1 - 1.4e-10 41.5 0.1 6e-05 23.5 0.0 3.2 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 OQR96891.1 - 3.9e-10 39.7 1.2 0.041 14.3 0.0 4.3 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.6 OQR96891.1 - 4.9e-08 33.1 0.6 0.074 13.4 0.2 3.6 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQR96891.1 - 1.9e-07 30.8 0.2 0.15 12.7 0.0 4.8 4 0 0 4 4 4 2 Ankyrin repeat DUF3618 PF12277.8 OQR96891.1 - 0.19 12.0 1.1 0.43 10.9 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3618) SF-assemblin PF06705.11 OQR96891.1 - 2 7.7 10.6 0.48 9.7 5.1 2.4 1 1 2 3 3 3 0 SF-assemblin/beta giardin CLZ PF16526.5 OQR96891.1 - 5.7 7.4 6.6 10 6.6 0.5 2.9 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels HMMR_N PF15905.5 OQR96892.1 - 0.00076 19.0 18.0 0.00076 19.0 18.0 5.0 1 1 4 5 5 5 1 Hyaluronan mediated motility receptor N-terminal Laminin_II PF06009.12 OQR96892.1 - 0.012 15.6 8.7 0.012 15.6 8.7 8.1 2 1 5 7 7 7 0 Laminin Domain II PKcGMP_CC PF16808.5 OQR96892.1 - 0.42 10.5 15.9 0.49 10.3 0.8 5.5 5 0 0 5 5 5 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Spc7 PF08317.11 OQR96892.1 - 7.4 5.4 129.3 0.028 13.3 17.9 5.5 2 2 3 5 5 5 0 Spc7 kinetochore protein Clat_adaptor_s PF01217.20 OQR96893.1 - 9e-55 184.5 1.3 1.1e-54 184.2 1.3 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain DUF1771 PF08590.10 OQR96894.1 - 2.6e-18 66.2 9.9 1.5e-17 63.7 10.5 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF1771) Smr PF01713.21 OQR96894.1 - 5.5e-10 39.5 0.3 2.6e-09 37.3 0.1 2.2 2 0 0 2 2 2 1 Smr domain zf_CCCH_4 PF18345.1 OQR96894.1 - 7.9e-08 32.1 9.9 2.6e-05 24.1 1.6 3.0 2 1 0 2 2 2 2 Zinc finger domain zf-CCCH_4 PF18044.1 OQR96894.1 - 0.00014 21.5 9.4 0.0058 16.4 0.3 2.7 2 1 0 2 2 2 2 CCCH-type zinc finger zf-CCCH PF00642.24 OQR96894.1 - 0.001 18.9 9.1 0.12 12.3 1.0 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.6 OQR96894.1 - 0.0011 19.3 5.4 0.018 15.5 0.2 2.4 2 0 0 2 2 2 1 RNA-binding, Nab2-type zinc finger Torus PF16131.5 OQR96894.1 - 0.018 15.7 11.1 0.019 15.6 1.0 2.9 2 1 1 3 3 3 0 Torus domain zf-CCCH_3 PF15663.5 OQR96894.1 - 3.3 8.0 7.8 25 5.1 6.4 2.2 1 1 0 1 1 1 0 Zinc-finger containing family Metallophos PF00149.28 OQR96895.1 - 3e-13 50.7 2.6 5.2e-13 50.0 2.6 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_C PF14008.6 OQR96895.1 - 5.9e-09 36.7 1.5 3.9e-08 34.0 0.2 2.8 3 0 0 3 3 3 1 Iron/zinc purple acid phosphatase-like protein C Pur_ac_phosph_N PF16656.5 OQR96895.1 - 8.8e-06 26.2 1.9 2.2e-05 25.0 0.1 2.5 3 0 0 3 3 3 1 Purple acid Phosphatase, N-terminal domain Metallophos_2 PF12850.7 OQR96895.1 - 0.011 15.9 0.1 2 8.6 0.0 2.2 2 0 0 2 2 2 0 Calcineurin-like phosphoesterase superfamily domain GP46 PF07409.12 OQR96895.1 - 0.019 14.7 0.1 0.035 13.8 0.1 1.4 1 0 0 1 1 1 0 Phage protein GP46 Tyrosinase PF00264.20 OQR96896.1 - 8.6e-23 81.8 0.3 1.8e-22 80.8 0.3 1.4 1 0 0 1 1 1 1 Common central domain of tyrosinase zf-C2HC5 PF06221.13 OQR96897.1 - 0.0085 16.1 0.2 0.015 15.3 0.2 1.4 1 0 0 1 1 1 1 Putative zinc finger motif, C2HC5-type PH_11 PF15413.6 OQR96897.1 - 0.037 14.4 0.0 0.076 13.4 0.0 1.6 1 1 0 1 1 1 0 Pleckstrin homology domain NinF PF05810.12 OQR96897.1 - 0.05 13.5 0.1 0.12 12.2 0.1 1.6 1 0 0 1 1 1 0 NinF protein TF_Zn_Ribbon PF08271.12 OQR96897.1 - 0.14 11.7 2.5 0.4 10.2 2.5 1.8 1 1 0 1 1 1 0 TFIIB zinc-binding Guanylate_kin PF00625.21 OQR96897.1 - 0.24 11.1 3.0 1.2 8.8 0.9 2.1 2 0 0 2 2 2 0 Guanylate kinase Mob1_phocein PF03637.17 OQR96903.1 - 0.015 15.3 2.6 0.096 12.7 0.5 2.0 1 1 1 2 2 2 0 Mob1/phocein family COMM_domain PF07258.14 OQR96903.1 - 0.064 13.4 0.1 0.44 10.7 0.0 2.3 1 1 2 3 3 3 0 COMM domain Coq4 PF05019.13 OQR96904.1 - 8.5e-89 296.6 0.0 1e-88 296.4 0.0 1.0 1 0 0 1 1 1 1 Coenzyme Q (ubiquinone) biosynthesis protein Coq4 Methyltransf_16 PF10294.9 OQR96905.1 - 5.9e-22 78.2 0.2 8.3e-22 77.7 0.2 1.1 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_23 PF13489.6 OQR96905.1 - 5.7e-10 39.3 0.0 8.1e-10 38.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 OQR96905.1 - 3.3e-07 30.0 0.7 4.4e-07 29.6 0.7 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_31 PF13847.6 OQR96905.1 - 3.7e-07 30.1 0.0 5.6e-07 29.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OQR96905.1 - 4.9e-05 24.0 0.0 0.00011 22.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 OQR96905.1 - 6.4e-05 22.6 0.2 0.00011 21.8 0.2 1.5 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_11 PF08241.12 OQR96905.1 - 0.00011 22.8 0.0 0.00025 21.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.15 OQR96905.1 - 0.00069 19.3 0.0 0.001 18.8 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_25 PF13649.6 OQR96905.1 - 0.001 19.7 0.2 0.0036 18.0 0.0 2.0 2 1 0 2 2 2 1 Methyltransferase domain FH2 PF02181.23 OQR96906.1 - 9.4e-75 252.0 1.0 2.2e-74 250.8 0.0 2.1 2 0 0 2 2 2 1 Formin Homology 2 Domain CCDC53 PF10152.9 OQR96906.1 - 1.1e-42 146.1 26.9 4.3e-10 40.2 0.1 6.7 2 1 4 6 6 6 5 Subunit CCDC53 of WASH complex Drf_GBD PF06371.13 OQR96906.1 - 5.5e-17 62.0 0.6 1.5e-16 60.5 0.6 1.8 1 0 0 1 1 1 1 Diaphanous GTPase-binding Domain Drf_FH3 PF06367.16 OQR96906.1 - 8.2e-12 45.1 0.6 8.2e-12 45.1 0.6 3.3 3 1 0 3 3 3 1 Diaphanous FH3 Domain DUF2802 PF10975.8 OQR96906.1 - 0.0002 21.4 2.8 17 5.7 0.1 6.1 6 0 0 6 6 6 0 Protein of unknown function (DUF2802) Allexi_40kDa PF05549.11 OQR96906.1 - 0.0073 15.8 0.2 0.0073 15.8 0.2 3.1 3 0 0 3 3 3 1 Allexivirus 40kDa protein SHE3 PF17078.5 OQR96906.1 - 0.011 15.4 7.4 0.5 10.0 0.9 2.4 2 0 0 2 2 2 0 SWI5-dependent HO expression protein 3 PI3K_P85_iSH2 PF16454.5 OQR96906.1 - 0.017 14.7 12.9 0.23 11.1 1.0 2.9 2 1 0 2 2 2 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain Rootletin PF15035.6 OQR96906.1 - 0.038 14.0 6.3 0.11 12.5 1.4 2.6 2 0 0 2 2 2 0 Ciliary rootlet component, centrosome cohesion CENP-F_leu_zip PF10473.9 OQR96906.1 - 0.24 11.4 9.1 0.3 11.1 2.1 2.9 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TPR_MLP1_2 PF07926.12 OQR96906.1 - 5.5 7.1 12.1 5.8 7.0 1.6 2.7 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein DHR10 PF18595.1 OQR96906.1 - 7.2 6.7 10.5 9.2 6.4 0.6 2.7 2 0 0 2 2 2 0 Designed helical repeat protein 10 domain TPH PF13868.6 OQR96907.1 - 0.00083 18.0 97.1 0.00083 18.0 97.1 1.8 2 0 0 2 2 2 1 Trichohyalin-plectin-homology domain HD PF01966.22 OQR96908.1 - 2e-06 28.0 0.1 7.1e-06 26.3 0.0 1.9 2 0 0 2 2 2 1 HD domain DUF4605 PF15378.6 OQR96908.1 - 0.012 15.5 1.7 0.022 14.6 1.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4605) T_hemolysin PF12261.8 OQR96908.1 - 0.055 13.2 0.0 0.16 11.7 0.0 1.7 2 0 0 2 2 2 0 Thermostable hemolysin Syja_N PF02383.18 OQR96909.1 - 1.3e-79 267.9 0.0 1.7e-79 267.4 0.0 1.2 1 0 0 1 1 1 1 SacI homology domain Complex1_LYR PF05347.15 OQR96910.1 - 0.0011 19.0 0.6 0.0016 18.4 0.6 1.3 1 0 0 1 1 1 1 Complex 1 protein (LYR family) KAP PF05804.12 OQR96911.1 - 3.7e-140 468.4 20.2 5.1e-140 467.9 20.2 1.1 1 0 0 1 1 1 1 Kinesin-associated protein (KAP) HSP33 PF01430.19 OQR96911.1 - 2e-27 96.3 0.2 3.8e-27 95.4 0.2 1.4 1 0 0 1 1 1 1 Hsp33 protein Arm PF00514.23 OQR96911.1 - 0.0028 17.6 0.2 1.6 8.9 0.0 4.4 5 0 0 5 5 5 1 Armadillo/beta-catenin-like repeat Glyco_hydro_18 PF00704.28 OQR96912.1 - 3e-30 106.0 1.2 4e-30 105.6 1.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Alpha-amylase PF00128.24 OQR96912.1 - 0.016 14.8 2.7 0.027 14.0 2.7 1.3 1 0 0 1 1 1 0 Alpha amylase, catalytic domain GHL15 PF14885.6 OQR96912.1 - 0.079 12.9 1.7 0.11 12.4 1.7 1.2 1 0 0 1 1 1 0 Hypothetical glycosyl hydrolase family 15 OATP PF03137.20 OQR96914.1 - 1.1e-29 103.1 14.9 2.7e-22 78.8 0.0 3.2 1 1 2 3 3 3 2 Organic Anion Transporter Polypeptide (OATP) family MFS_1 PF07690.16 OQR96914.1 - 2.4e-27 95.8 33.6 2.4e-27 95.8 33.6 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 OQR96914.1 - 1.3e-16 60.5 10.9 1.3e-16 60.5 10.9 2.5 2 1 0 2 2 2 1 Sugar (and other) transporter Bud13 PF09736.9 OQR96915.1 - 1.3e-42 145.7 8.7 1.3e-42 145.7 8.7 4.7 3 2 0 4 4 4 1 Pre-mRNA-splicing factor of RES complex Acetate_kinase PF00871.17 OQR96916.1 - 2.4e-141 471.0 0.0 2.7e-141 470.8 0.0 1.0 1 0 0 1 1 1 1 Acetokinase family CBF PF03914.17 OQR96917.1 - 3.1e-55 186.8 0.2 3.1e-55 186.8 0.2 3.2 3 1 0 3 3 3 1 CBF/Mak21 family Ribosomal_60s PF00428.19 OQR96917.1 - 0.0013 19.3 3.2 0.0013 19.3 3.2 4.3 4 0 0 4 4 4 1 60s Acidic ribosomal protein BUD22 PF09073.10 OQR96917.1 - 0.0043 16.4 28.5 0.0043 16.4 28.5 2.2 2 0 0 2 2 2 2 BUD22 Cnd1 PF12717.7 OQR96917.1 - 0.048 13.7 2.0 0.062 13.3 0.5 2.1 3 0 0 3 3 3 0 non-SMC mitotic condensation complex subunit 1 AAA_22 PF13401.6 OQR96917.1 - 0.094 13.0 0.3 0.31 11.3 0.1 2.0 2 0 0 2 2 2 0 AAA domain Flavokinase PF01687.17 OQR96918.1 - 3.6e-31 107.7 0.0 4.2e-31 107.5 0.0 1.0 1 0 0 1 1 1 1 Riboflavin kinase PTA_PTB PF01515.19 OQR96919.1 - 1.3e-111 373.0 2.0 2.2e-111 372.2 2.0 1.4 1 0 0 1 1 1 1 Phosphate acetyl/butaryl transferase AAA_26 PF13500.6 OQR96919.1 - 1e-18 67.9 0.0 3.3e-18 66.2 0.0 1.9 1 1 0 1 1 1 1 AAA domain DRTGG PF07085.12 OQR96919.1 - 1.3e-13 50.6 0.0 5.6e-13 48.6 0.0 2.2 1 0 0 1 1 1 1 DRTGG domain Ank_2 PF12796.7 OQR96920.1 - 1.3e-31 109.1 0.5 2.4e-13 50.5 0.0 3.2 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQR96920.1 - 1.5e-31 108.3 0.1 7.8e-10 39.1 0.0 3.7 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 OQR96920.1 - 1.6e-23 82.1 0.1 1.3e-06 28.6 0.0 5.4 6 0 0 6 6 6 4 Ankyrin repeat Ank_5 PF13857.6 OQR96920.1 - 4.6e-21 74.6 0.3 2e-07 31.1 0.0 4.1 2 2 3 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQR96920.1 - 1.9e-18 64.6 0.4 0.0007 19.9 0.0 5.5 6 0 0 6 6 6 4 Ankyrin repeat Mito_carr PF00153.27 OQR96921.1 - 8.5e-49 163.4 5.9 5.7e-16 58.2 0.2 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein FBPase PF00316.20 OQR96922.1 - 3e-67 225.8 0.1 4e-67 225.4 0.1 1.2 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase, N-terminal domain Inositol_P PF00459.25 OQR96922.1 - 0.013 15.0 0.0 0.036 13.6 0.0 1.6 2 0 0 2 2 2 0 Inositol monophosphatase family NIP_1 PF08995.10 OQR96922.1 - 0.11 12.8 0.0 0.3 11.5 0.0 1.7 1 0 0 1 1 1 0 Necrosis inducing protein-1 Hep_59 PF07052.11 OQR96923.1 - 2e-09 38.1 1.9 2e-09 38.1 1.9 3.0 2 1 1 3 3 3 1 Hepatocellular carcinoma-associated antigen 59 DUF2063 PF09836.9 OQR96923.1 - 0.023 14.9 0.0 0.046 14.0 0.0 1.5 1 0 0 1 1 1 0 Putative DNA-binding domain Sec7 PF01369.20 OQR97031.1 - 1e-55 188.3 0.1 2.4e-55 187.0 0.1 1.7 1 0 0 1 1 1 1 Sec7 domain bZIP_1 PF00170.21 OQR97031.1 - 2.8e-12 46.5 9.0 1e-11 44.7 9.0 2.0 1 0 0 1 1 1 1 bZIP transcription factor Sec7_N PF12783.7 OQR97031.1 - 5.4e-11 42.7 2.5 5.4e-11 42.7 2.5 3.0 4 0 0 4 4 4 1 Guanine nucleotide exchange factor in Golgi transport N-terminal bZIP_2 PF07716.15 OQR97031.1 - 2.2e-08 34.0 9.1 2.2e-08 34.0 9.1 2.3 2 0 0 2 2 2 1 Basic region leucine zipper PH PF00169.29 OQR97031.1 - 1.7e-05 25.3 0.0 5.2e-05 23.7 0.0 2.0 1 0 0 1 1 1 1 PH domain Apolipoprotein PF01442.18 OQR97031.1 - 0.1 12.4 14.9 0.022 14.6 6.4 2.7 1 1 1 2 2 2 0 Apolipoprotein A1/A4/E domain LTXXQ PF07813.12 OQR97031.1 - 6.7 7.5 10.2 1.4 9.6 2.8 3.0 2 0 0 2 2 2 0 LTXXQ motif family protein Ank_2 PF12796.7 OQR97032.1 - 7.9e-45 151.4 11.7 1.3e-10 41.7 0.3 7.1 6 2 2 8 8 8 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQR97032.1 - 1.1e-30 105.6 6.1 1.1e-07 32.2 0.2 8.9 7 2 2 9 9 9 6 Ankyrin repeats (many copies) Ank_5 PF13857.6 OQR97032.1 - 1.4e-28 98.5 11.0 0.00018 21.7 0.1 9.3 5 3 4 9 9 9 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQR97032.1 - 2.3e-28 95.1 9.9 0.0012 19.1 0.0 11.4 11 0 0 11 11 11 6 Ankyrin repeat Ank PF00023.30 OQR97032.1 - 1.5e-18 66.4 16.6 0.016 15.7 0.2 10.7 11 0 0 11 11 11 7 Ankyrin repeat PKD_channel PF08016.12 OQR97032.1 - 0.00097 17.9 18.3 0.039 12.6 11.2 2.3 2 0 0 2 2 2 2 Polycystin cation channel Tyrosinase PF00264.20 OQR97033.1 - 5.9e-09 36.5 0.1 9.4e-08 32.6 0.1 2.2 1 1 0 1 1 1 1 Common central domain of tyrosinase DUF1097 PF06496.11 OQR97034.1 - 0.085 13.0 13.2 0.089 12.9 11.6 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1097) DUF2070 PF09843.9 OQR97034.1 - 0.29 9.4 16.0 0.36 9.0 16.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) HPP PF04982.13 OQR97034.1 - 2.1 8.6 7.9 8.4 6.6 1.0 2.9 1 1 1 3 3 3 0 HPP family Chromate_transp PF02417.15 OQR97034.1 - 9.9 6.3 12.7 12 6.0 0.8 2.4 1 1 1 2 2 2 0 Chromate transporter TPR_12 PF13424.6 OQR97035.1 - 3.9e-13 49.5 0.1 2.6e-05 24.4 0.0 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.6 OQR97035.1 - 1.5e-07 30.9 0.1 0.046 13.8 0.0 5.0 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_1 PF00515.28 OQR97035.1 - 2.7e-07 30.1 0.0 1.5 8.8 0.0 4.6 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.6 OQR97035.1 - 3.7e-07 29.9 0.0 0.13 12.6 0.0 4.3 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 OQR97035.1 - 0.0071 16.4 0.0 56 4.2 0.0 4.5 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_17 PF13431.6 OQR97035.1 - 0.015 15.6 0.0 4 8.0 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.6 OQR97035.1 - 0.021 14.7 0.1 7.5 6.6 0.0 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat EcKinase PF02958.20 OQR97036.1 - 3.1e-16 59.5 0.2 9.6e-16 57.9 0.2 2.0 1 1 0 1 1 1 1 Ecdysteroid kinase DUF1679 PF07914.11 OQR97036.1 - 1.6e-13 50.3 0.1 2.5e-13 49.7 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1679) APH PF01636.23 OQR97036.1 - 3.5e-11 43.5 0.0 4.7e-11 43.1 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 OQR97036.1 - 0.0019 17.8 0.0 0.0029 17.2 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.22 OQR97036.1 - 0.0046 16.6 0.1 0.013 15.1 0.0 1.7 2 0 0 2 2 2 1 RIO1 family Syja_N PF02383.18 OQR97037.1 - 8.6e-82 275.0 0.0 1.2e-81 274.6 0.0 1.2 1 0 0 1 1 1 1 SacI homology domain TAFII55_N PF04658.13 OQR97038.1 - 2e-20 73.1 0.0 4.8e-20 71.9 0.0 1.6 1 1 0 1 1 1 1 TAFII55 protein conserved region C2 PF00168.30 OQR97039.1 - 3.7e-90 297.0 2.7 1.8e-20 73.1 0.0 8.6 8 0 0 8 8 8 8 C2 domain cNMP_binding PF00027.29 OQR97039.1 - 1.3e-18 66.8 0.2 1.3e-10 41.2 0.1 3.0 2 1 0 2 2 2 2 Cyclic nucleotide-binding domain ubiquitin PF00240.23 OQR97039.1 - 2.8e-11 43.0 0.8 2e-10 40.2 0.1 2.7 2 0 0 2 2 2 1 Ubiquitin family FerI PF08151.12 OQR97039.1 - 0.0036 17.4 0.0 0.012 15.7 0.0 1.8 1 0 0 1 1 1 1 FerI (NUC094) domain Beta_helix PF13229.6 OQR97041.1 - 0.0001 22.2 7.0 0.00048 20.0 7.0 2.1 1 1 0 1 1 1 1 Right handed beta helix region Methyltransf_16 PF10294.9 OQR97105.1 - 5.7e-28 97.8 0.2 7.5e-28 97.4 0.2 1.1 1 0 0 1 1 1 1 Lysine methyltransferase PrmA PF06325.13 OQR97105.1 - 0.0056 16.1 0.1 0.0076 15.7 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Ricin_B_lectin PF00652.22 OQR97106.1 - 7.2e-28 97.4 15.4 7.9e-15 55.2 1.4 3.1 2 1 0 3 3 3 2 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.6 OQR97106.1 - 6.6e-12 46.0 11.7 1.5e-06 28.8 2.2 3.7 2 1 1 3 3 3 3 Ricin-type beta-trefoil lectin domain-like Glyco_hydro_3_C PF01915.22 OQR97106.1 - 2.6e-09 37.3 0.0 7.8e-09 35.8 0.0 1.8 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain CDtoxinA PF03498.14 OQR97106.1 - 5.7e-08 32.5 0.2 0.0035 16.9 0.0 2.4 2 0 0 2 2 2 2 Cytolethal distending toxin A/C domain Fn3-like PF14310.6 OQR97106.1 - 2.1e-07 30.9 0.0 4.3e-07 30.0 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain RCC1 PF00415.18 OQR97108.1 - 5.1e-101 331.2 27.9 8.5e-17 61.5 1.1 7.4 7 0 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 OQR97108.1 - 3.5e-53 176.5 39.3 3.9e-10 39.2 1.1 8.4 8 0 0 8 8 8 6 Regulator of chromosome condensation (RCC1) repeat BTB PF00651.31 OQR97108.1 - 1.5e-27 96.0 0.3 1.1e-24 86.8 0.0 2.4 1 1 1 2 2 2 2 BTB/POZ domain Syntaxin_2 PF14523.6 OQR97108.1 - 8.3e-13 48.6 12.4 1.1e-12 48.2 6.4 2.5 2 0 0 2 2 2 1 Syntaxin-like protein BACK PF07707.15 OQR97108.1 - 7.3e-06 26.0 0.3 6.3e-05 23.0 0.1 2.5 2 0 0 2 2 2 1 BTB And C-terminal Kelch Syntaxin PF00804.25 OQR97108.1 - 0.0033 17.1 8.8 0.037 13.7 8.8 2.3 1 1 0 1 1 1 1 Syntaxin DUF1921 PF09081.10 OQR97108.1 - 0.012 15.8 1.3 4.9 7.5 0.0 4.4 5 0 0 5 5 5 0 Domain of unknown function (DUF1921) RB_A PF01858.17 OQR97108.1 - 0.027 14.3 0.4 0.058 13.2 0.4 1.5 1 0 0 1 1 1 0 Retinoblastoma-associated protein A domain RFX1_trans_act PF04589.13 OQR97108.1 - 0.067 13.4 0.3 0.16 12.2 0.3 1.6 1 0 0 1 1 1 0 RFX1 transcription activation region SNARE PF05739.19 OQR97108.1 - 0.073 13.1 0.3 0.18 11.9 0.3 1.7 1 0 0 1 1 1 0 SNARE domain AAA_13 PF13166.6 OQR97108.1 - 0.12 11.0 10.5 0.013 14.2 4.8 1.9 1 1 1 2 2 2 0 AAA domain SUKH-3 PF14433.6 OQR97108.1 - 0.15 12.5 0.3 44 4.5 0.0 3.1 2 1 1 3 3 3 0 SUKH-3 immunity protein TMF_TATA_bd PF12325.8 OQR97108.1 - 1.3 9.2 5.1 1.1 9.5 1.3 2.3 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding DUF883 PF05957.13 OQR97108.1 - 2 9.0 4.6 32 5.2 0.1 2.5 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) Mer2 PF09074.10 OQR97108.1 - 4 7.2 8.1 6.3 6.6 7.5 1.7 1 1 0 1 1 1 0 Mer2 CorA PF01544.18 OQR97108.1 - 4.2 6.6 7.7 21 4.3 7.4 2.2 1 1 0 1 1 1 0 CorA-like Mg2+ transporter protein T3SSipB PF16535.5 OQR97108.1 - 5.1 7.6 7.3 2.5 8.5 1.7 2.2 1 1 0 2 2 2 0 Type III cell invasion protein SipB Laminin_II PF06009.12 OQR97108.1 - 6.2 6.8 9.6 4.8 7.2 0.6 3.1 2 1 1 3 3 3 0 Laminin Domain II Pkinase PF00069.25 OQR97109.1 - 5.9e-41 140.6 0.0 9.4e-41 139.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQR97109.1 - 7.6e-37 127.0 0.0 1.1e-36 126.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OQR97109.1 - 0.0011 17.8 0.0 0.0016 17.3 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 OQR97109.1 - 0.002 17.5 0.0 0.0033 16.8 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Ank_2 PF12796.7 OQR97110.1 - 1.7e-41 140.7 11.5 2.1e-14 53.9 0.0 5.0 2 2 3 5 5 5 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQR97110.1 - 4.5e-35 119.6 13.0 1.3e-10 41.6 0.1 6.8 2 2 5 7 7 7 6 Ankyrin repeats (many copies) Ank_5 PF13857.6 OQR97110.1 - 1.7e-23 82.4 7.5 5.6e-07 29.7 0.3 5.6 2 2 4 6 6 6 6 Ankyrin repeats (many copies) Ank PF00023.30 OQR97110.1 - 6.8e-22 76.9 16.9 4.1e-05 23.8 0.0 8.0 8 0 0 8 8 8 6 Ankyrin repeat Ank_3 PF13606.6 OQR97110.1 - 3.1e-18 63.9 10.6 0.00014 22.0 0.0 8.3 8 0 0 8 8 8 4 Ankyrin repeat WW PF00397.26 OQR97110.1 - 5.3e-09 36.0 4.7 1e-08 35.1 4.7 1.5 1 0 0 1 1 1 1 WW domain GYF PF02213.16 OQR97111.1 - 1.2e-17 63.3 0.4 2.6e-17 62.2 0.4 1.6 1 0 0 1 1 1 1 GYF domain GYF_2 PF14237.6 OQR97111.1 - 0.00061 19.5 0.1 0.0028 17.4 0.1 2.2 1 0 0 1 1 1 1 GYF domain 2 Mob1_phocein PF03637.17 OQR97112.1 - 9.2e-61 204.7 1.6 1.4e-60 204.2 0.1 2.0 3 0 0 3 3 3 1 Mob1/phocein family Exonuc_VII_L PF02601.15 OQR97112.1 - 1.8 8.1 7.3 2.6 7.5 7.3 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit MatE PF01554.18 OQR97113.1 - 2.3e-50 170.4 39.4 9.8e-27 93.6 8.1 3.3 3 1 1 4 4 4 3 MatE Myosin_head PF00063.21 OQR97115.1 - 2e-219 730.3 0.9 2e-219 730.3 0.9 1.7 2 0 0 2 2 2 1 Myosin head (motor domain) WW PF00397.26 OQR97115.1 - 1.9e-09 37.4 0.0 4.1e-09 36.4 0.0 1.6 1 0 0 1 1 1 1 WW domain IQ PF00612.27 OQR97115.1 - 4.2e-07 29.2 19.8 0.07 13.0 0.4 5.8 5 0 0 5 5 5 3 IQ calmodulin-binding motif DUF3584 PF12128.8 OQR97115.1 - 0.0013 16.4 16.9 0.002 15.7 16.9 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) Myosin_N PF02736.19 OQR97115.1 - 0.0097 15.7 0.4 0.0097 15.7 0.4 1.9 2 0 0 2 2 2 1 Myosin N-terminal SH3-like domain AAA_16 PF13191.6 OQR97115.1 - 0.019 15.4 0.1 0.11 12.9 0.0 2.3 2 0 0 2 2 2 0 AAA ATPase domain AAA_22 PF13401.6 OQR97115.1 - 0.022 15.1 0.1 0.13 12.5 0.0 2.3 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 OQR97115.1 - 3.5 8.1 5.5 1.2 9.7 0.0 2.8 2 1 0 2 2 2 0 ABC transporter bZIP_1 PF00170.21 OQR97115.1 - 3.7 7.7 17.9 0.52 10.5 3.5 3.4 3 0 0 3 3 3 0 bZIP transcription factor Fer2_BFD PF04324.15 OQR97116.1 - 0.13 12.6 0.1 0.23 11.8 0.1 1.4 1 0 0 1 1 1 0 BFD-like [2Fe-2S] binding domain Ank_2 PF12796.7 OQR97165.1 - 1.1e-33 115.6 16.8 4e-08 33.7 0.0 6.9 3 2 2 7 7 7 6 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OQR97165.1 - 1.2e-20 73.2 19.3 0.0013 18.9 0.1 12.8 7 4 7 14 14 14 6 Ankyrin repeats (many copies) Ank_4 PF13637.6 OQR97165.1 - 2.4e-20 72.6 14.5 0.1 13.2 0.0 10.2 6 3 3 9 9 9 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQR97165.1 - 2.2e-16 58.3 14.2 2.2 9.1 0.0 14.1 15 2 2 17 17 17 4 Ankyrin repeat Ank PF00023.30 OQR97165.1 - 0.0018 18.7 14.6 24 5.6 0.3 9.1 6 3 2 8 8 8 1 Ankyrin repeat DUF5049 PF16468.5 OQR97165.1 - 0.0027 17.6 0.2 30 4.6 0.1 4.7 5 0 0 5 5 5 0 Domain of unknown function (DUF5049) PH PF00169.29 OQR97166.1 - 0.0049 17.4 0.0 0.017 15.7 0.0 1.8 1 1 0 1 1 1 1 PH domain PH PF00169.29 OQR97167.1 - 1.1e-43 148.0 0.8 1.8e-06 28.4 0.0 8.6 8 1 0 8 8 8 8 PH domain PH_11 PF15413.6 OQR97167.1 - 0.00025 21.4 0.3 26 5.3 0.0 6.4 6 0 0 6 6 6 1 Pleckstrin homology domain PDZ PF00595.24 OQR97167.1 - 0.0068 16.7 0.0 0.016 15.5 0.0 1.6 1 0 0 1 1 1 1 PDZ domain HicA_toxin PF07927.12 OQR97167.1 - 0.054 13.5 0.3 6.4 6.9 0.1 3.3 3 0 0 3 3 3 0 HicA toxin of bacterial toxin-antitoxin, DUF4694 PF15765.5 OQR97167.1 - 0.11 12.5 0.1 0.43 10.6 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4694) PH_10 PF15411.6 OQR97167.1 - 0.76 10.0 4.2 40 4.5 0.0 4.0 5 0 0 5 5 5 0 Pleckstrin homology domain Hus1 PF04005.12 OQR97168.1 - 4.9e-48 163.7 0.1 6.1e-48 163.4 0.1 1.0 1 0 0 1 1 1 1 Hus1-like protein Ras PF00071.22 OQR97169.1 - 3.3e-61 205.6 0.2 4.5e-61 205.2 0.2 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OQR97169.1 - 1.5e-32 112.3 0.0 2.7e-32 111.5 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase COPI_assoc PF08507.10 OQR97169.1 - 5e-15 55.7 3.6 1.1e-14 54.6 3.6 1.5 1 0 0 1 1 1 1 COPI associated protein Arf PF00025.21 OQR97169.1 - 1.1e-12 47.8 0.1 1.7e-12 47.2 0.1 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 OQR97169.1 - 0.00014 21.9 0.0 0.00026 21.1 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 OQR97169.1 - 0.00096 19.1 0.0 0.77 9.7 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 OQR97169.1 - 0.0023 17.5 0.0 0.0077 15.8 0.0 1.8 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 OQR97169.1 - 0.0028 17.1 0.0 0.0039 16.6 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_22 PF13401.6 OQR97169.1 - 0.16 12.2 0.1 0.63 10.3 0.1 2.0 1 1 0 1 1 1 0 AAA domain DAP3 PF10236.9 OQR97169.1 - 0.16 11.1 0.0 0.3 10.2 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 Tom37 PF10568.9 OQR97170.1 - 3.2e-23 82.4 0.0 5.5e-23 81.6 0.0 1.4 1 0 0 1 1 1 1 Outer mitochondrial membrane transport complex protein GST_N_4 PF17172.4 OQR97170.1 - 5.3e-15 56.0 0.0 9.4e-15 55.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase N-terminal domain GST_C_6 PF17171.4 OQR97170.1 - 1.6e-11 43.8 0.1 4.2e-11 42.5 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 OQR97170.1 - 0.0011 19.0 0.0 0.0025 17.8 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Ion_trans PF00520.31 OQR97171.1 - 0.00035 19.9 38.4 0.0033 16.7 36.9 2.2 1 1 0 1 1 1 1 Ion transport protein Myb_DNA-binding PF00249.31 OQR97172.1 - 9.4e-35 118.6 10.8 2e-12 47.1 1.0 3.3 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OQR97172.1 - 3.8e-32 110.3 4.4 6e-16 58.4 0.1 3.6 2 1 1 3 3 3 3 Myb-like DNA-binding domain SLIDE PF09111.10 OQR97172.1 - 0.00024 21.1 0.0 0.33 11.0 0.1 3.0 2 1 1 3 3 3 2 SLIDE Rap1_C PF11626.8 OQR97172.1 - 0.47 10.6 3.8 2.5 8.2 1.7 2.9 1 1 1 2 2 2 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain Myb_DNA-bind_4 PF13837.6 OQR97172.1 - 3.3 8.1 11.8 9 6.8 0.2 3.6 2 1 1 3 3 3 0 Myb/SANT-like DNA-binding domain SpoIIIAH PF12685.7 OQR97173.1 - 0.00045 20.1 0.6 0.00054 19.8 0.6 1.1 1 0 0 1 1 1 1 SpoIIIAH-like protein DUF2252 PF10009.9 OQR97173.1 - 0.61 9.1 3.1 0.71 8.9 3.1 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2252) 2OG-FeII_Oxy_3 PF13640.6 OQR97174.1 - 8.8e-08 32.9 0.1 1.4e-07 32.3 0.1 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily E1-E2_ATPase PF00122.20 OQR97175.1 - 1.6e-21 76.7 1.9 6.8e-20 71.3 0.4 2.7 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 OQR97175.1 - 9.1e-12 45.7 1.2 2.6e-05 24.6 0.1 3.5 3 1 0 3 3 3 2 haloacid dehalogenase-like hydrolase Trypsin PF00089.26 OQR97175.1 - 5.5e-05 23.1 0.0 0.0002 21.2 0.0 1.9 2 0 0 2 2 2 1 Trypsin Trypsin_2 PF13365.6 OQR97175.1 - 0.0007 20.5 0.1 0.0019 19.1 0.0 1.9 1 1 0 1 1 1 1 Trypsin-like peptidase domain Cation_ATPase PF13246.6 OQR97175.1 - 0.0013 18.7 0.0 0.0037 17.3 0.0 1.8 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 OQR97175.1 - 0.02 14.7 0.0 0.67 9.6 0.0 2.7 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 OQR97175.1 - 0.062 13.0 0.0 0.16 11.7 0.0 1.7 1 0 0 1 1 1 0 Cation transporter/ATPase, N-terminus DUF2839 PF10999.8 OQR97175.1 - 0.18 12.2 0.1 0.56 10.6 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2839) TMEM154 PF15102.6 OQR97175.1 - 0.49 10.3 9.6 0.064 13.2 4.6 2.1 2 0 0 2 2 2 0 TMEM154 protein family RIFIN PF02009.16 OQR97175.1 - 6.3 6.6 7.1 8.9 6.1 0.6 2.4 2 0 0 2 2 2 0 Rifin PAM2 PF07145.15 OQR97176.1 - 0.0059 16.2 0.0 0.016 14.9 0.0 1.8 2 0 0 2 2 2 1 Ataxin-2 C-terminal region Peptidase_C26 PF07722.13 OQR97178.1 - 1.4e-19 70.7 0.0 4.6e-18 65.8 0.0 2.5 1 1 0 1 1 1 1 Peptidase C26 GATase PF00117.28 OQR97178.1 - 1.2e-09 38.3 0.0 2.3e-09 37.3 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase class-I SNO PF01174.19 OQR97178.1 - 0.032 14.1 0.0 0.082 12.7 0.0 1.8 1 1 0 1 1 1 0 SNO glutamine amidotransferase family DUF2275 PF10039.9 OQR97178.1 - 0.21 11.7 0.1 0.94 9.5 0.0 2.0 2 1 0 2 2 2 0 Predicted integral membrane protein (DUF2275) CN_hydrolase PF00795.22 OQR97179.1 - 6e-63 212.6 0.0 6.7e-63 212.4 0.0 1.0 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase vATP-synt_AC39 PF01992.16 OQR97180.1 - 6.1e-86 289.0 0.2 1.1e-85 288.2 0.2 1.2 1 0 0 1 1 1 1 ATP synthase (C/AC39) subunit Methyltransf_11 PF08241.12 OQR97180.1 - 1.9e-12 47.6 0.0 5.2e-12 46.2 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OQR97180.1 - 8e-10 38.8 0.0 1.7e-09 37.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OQR97180.1 - 2.8e-09 37.6 0.0 6.3e-09 36.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OQR97180.1 - 1.7e-05 25.5 0.0 4.6e-05 24.1 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OQR97180.1 - 0.0001 22.1 0.0 0.00053 19.8 0.0 2.1 2 1 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 OQR97180.1 - 0.00041 19.8 0.0 0.002 17.5 0.0 1.9 1 1 1 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_7 PF03492.15 OQR97180.1 - 0.017 14.3 0.1 0.035 13.3 0.1 1.4 1 0 0 1 1 1 0 SAM dependent carboxyl methyltransferase zf-C3HC4_3 PF13920.6 OQR97181.1 - 1.6e-09 37.5 10.4 2.9e-09 36.6 10.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 OQR97181.1 - 6.4e-09 36.0 14.7 1.1e-08 35.2 14.7 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 OQR97181.1 - 2.9e-08 33.4 13.6 5.4e-08 32.5 13.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OQR97181.1 - 6.1e-08 32.6 7.6 1.1e-07 31.7 5.7 2.2 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4 PF00097.25 OQR97181.1 - 1e-06 28.5 13.4 1.9e-06 27.6 13.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OQR97181.1 - 6e-06 26.1 12.0 1e-05 25.4 12.0 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.7 OQR97181.1 - 2.6e-05 24.4 8.1 5.1e-05 23.5 8.1 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_4 PF15227.6 OQR97181.1 - 4.2e-05 23.6 11.0 9.1e-05 22.5 11.0 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 OQR97181.1 - 8e-05 22.4 9.4 0.00013 21.7 9.4 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_6 PF14835.6 OQR97181.1 - 0.0018 18.1 6.0 0.004 17.0 6.0 1.5 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-ANAPC11 PF12861.7 OQR97181.1 - 0.018 15.1 4.4 0.034 14.2 4.4 1.3 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_11 PF17123.5 OQR97181.1 - 0.019 14.7 5.9 0.038 13.7 5.9 1.6 1 0 0 1 1 1 0 RING-like zinc finger GREB1 PF15782.5 OQR97182.1 - 1.9 5.5 11.9 2.4 5.2 11.9 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Tup_N PF08581.10 OQR97182.1 - 3.2 8.1 10.0 0.65 10.3 0.1 3.0 3 0 0 3 3 3 0 Tup N-terminal PhosphMutase PF10143.9 OQR97196.1 - 2.2e-53 180.6 0.0 3.5e-53 180.0 0.0 1.3 1 0 0 1 1 1 1 2,3-bisphosphoglycerate-independent phosphoglycerate mutase Metalloenzyme PF01676.18 OQR97196.1 - 1.1e-31 110.1 0.0 1.4e-31 109.8 0.0 1.0 1 0 0 1 1 1 1 Metalloenzyme superfamily Phosphodiest PF01663.22 OQR97196.1 - 1.2e-05 25.1 0.0 1.8e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 OQR97196.1 - 0.001 18.6 0.0 0.0017 17.8 0.0 1.4 1 0 0 1 1 1 1 Sulfatase Alk_phosphatase PF00245.20 OQR97196.1 - 0.0012 17.9 0.1 0.002 17.1 0.1 1.3 1 0 0 1 1 1 1 Alkaline phosphatase Cofilin_ADF PF00241.20 OQR97197.1 - 6.6e-34 116.3 0.1 7.4e-34 116.2 0.1 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein Pkinase_Tyr PF07714.17 OQR97198.1 - 8e-23 81.0 0.0 1.6e-22 80.0 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OQR97198.1 - 8.8e-16 58.0 0.0 1.7e-15 57.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Ank_4 PF13637.6 OQR97199.1 - 3.8e-15 56.1 1.3 4.8e-07 30.2 0.2 2.6 2 1 0 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 OQR97199.1 - 4e-13 49.8 3.6 1.4e-07 32.0 0.2 2.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OQR97199.1 - 3e-12 45.6 0.7 0.00085 19.6 0.1 3.8 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.6 OQR97199.1 - 2.6e-07 30.8 4.9 0.00031 21.0 0.9 3.2 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 OQR97199.1 - 1.1e-06 28.9 1.2 0.11 13.0 0.0 3.4 4 0 0 4 4 4 2 Ankyrin repeat Ank_2 PF12796.7 OQR97200.1 - 1.1e-54 182.9 11.1 1.1e-12 48.4 0.5 5.2 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQR97200.1 - 3.9e-43 145.3 16.9 1.2e-09 38.5 0.1 8.3 2 2 8 10 10 10 8 Ankyrin repeats (many copies) Ank_5 PF13857.6 OQR97200.1 - 5.1e-42 141.4 14.4 6.6e-10 39.0 0.2 8.8 3 1 7 10 10 10 6 Ankyrin repeats (many copies) Ank PF00023.30 OQR97200.1 - 1e-34 117.4 23.2 3.7e-05 24.0 0.1 10.0 9 1 1 10 10 10 9 Ankyrin repeat Ank_3 PF13606.6 OQR97200.1 - 1.1e-32 108.4 16.1 0.00028 21.1 0.1 9.5 9 0 0 9 9 9 8 Ankyrin repeat VWA_3_C PF18571.1 OQR97200.1 - 0.0022 17.8 0.3 77 3.3 0.0 5.4 6 0 0 6 6 6 0 von Willebrand factor type A C-terminal domain PCSK9_C3 PF18463.1 OQR97200.1 - 0.011 15.9 0.3 11 6.3 0.0 3.6 4 0 0 4 4 4 0 Proprotein convertase subtilisin-like/kexin type 9 C-terminal domain Cyclin_N PF00134.23 OQR97200.1 - 0.21 11.4 0.7 60 3.4 0.0 3.6 3 1 1 4 4 4 0 Cyclin, N-terminal domain Solute_trans_a PF03619.16 OQR97201.1 - 3.7e-121 403.7 38.8 3.4e-82 275.9 18.4 2.3 2 0 0 2 2 2 2 Organic solute transporter Ostalpha Polysacc_deac_1 PF01522.21 OQR97201.1 - 3.9e-21 75.2 0.0 9.3e-21 74.0 0.0 1.6 1 0 0 1 1 1 1 Polysaccharide deacetylase Dynamin_N PF00350.23 OQR97202.1 - 1.1e-12 48.4 0.0 1.4e-11 44.7 0.0 2.2 1 1 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.23 OQR97202.1 - 9.7e-07 28.9 0.0 2.8e-06 27.4 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 OQR97202.1 - 0.0023 17.8 0.3 0.43 10.5 0.0 3.1 3 0 0 3 3 3 1 RsgA GTPase FtsK_SpoIIIE PF01580.18 OQR97202.1 - 0.021 14.2 0.1 0.037 13.4 0.1 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family Roc PF08477.13 OQR97202.1 - 0.021 15.0 0.0 1.7 8.9 0.0 2.3 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Septin PF00735.18 OQR97202.1 - 0.12 11.7 0.0 0.21 10.8 0.0 1.4 1 0 0 1 1 1 0 Septin G-alpha PF00503.20 OQR97202.1 - 0.12 11.5 0.2 0.8 8.8 0.0 2.1 2 0 0 2 2 2 0 G-protein alpha subunit FeoB_N PF02421.18 OQR97202.1 - 0.13 11.8 0.2 2.5 7.6 0.1 2.5 1 1 1 2 2 2 0 Ferrous iron transport protein B Kinesin PF00225.23 OQR97203.1 - 2e-97 326.1 3.3 2e-97 326.1 3.3 3.2 5 0 0 5 5 5 1 Kinesin motor domain Microtub_bd PF16796.5 OQR97203.1 - 3.1e-48 163.5 0.4 3.1e-48 163.5 0.4 2.8 2 1 0 2 2 2 1 Microtubule binding DUF2722 PF10846.8 OQR97203.1 - 0.0041 16.1 15.1 0.0041 16.1 15.1 3.1 3 0 0 3 3 3 1 Protein of unknown function (DUF2722) AAA_22 PF13401.6 OQR97203.1 - 1.1 9.6 5.5 1.6 9.0 0.0 3.2 2 1 0 2 2 2 0 AAA domain GDI PF00996.18 OQR97204.1 - 8.6e-199 660.5 0.1 1e-198 660.2 0.1 1.0 1 0 0 1 1 1 1 GDP dissociation inhibitor NAD_binding_8 PF13450.6 OQR97204.1 - 0.026 14.8 0.1 0.082 13.2 0.0 1.9 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain ABC1 PF03109.16 OQR97205.1 - 1.7e-20 73.3 0.0 3.5e-20 72.3 0.0 1.5 1 0 0 1 1 1 1 ABC1 family PALP PF00291.25 OQR97205.1 - 2.7e-10 40.1 0.0 5.2e-10 39.2 0.0 1.4 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Pkinase PF00069.25 OQR97205.1 - 1.1e-08 34.8 0.0 0.0007 19.0 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain RIO1 PF01163.22 OQR97205.1 - 0.0026 17.4 0.0 0.005 16.5 0.0 1.4 1 0 0 1 1 1 1 RIO1 family Pkinase_Tyr PF07714.17 OQR97205.1 - 0.0051 16.1 0.1 0.11 11.8 0.1 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 OQR97205.1 - 0.018 14.9 0.1 0.044 13.7 0.1 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family DUF485 PF04341.12 OQR97205.1 - 0.45 10.5 3.5 1 9.4 3.5 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF485 Metallophos PF00149.28 OQR97206.1 - 2.1e-15 57.7 0.5 4.4e-15 56.7 0.3 1.6 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase PI3K_P85_iSH2 PF16454.5 OQR97207.1 - 0.0029 17.2 11.6 0.0047 16.5 11.6 1.4 1 1 0 1 1 1 1 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain Fib_alpha PF08702.10 OQR97207.1 - 0.029 14.6 7.8 0.045 13.9 7.8 1.3 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family PBC PF03792.13 OQR97207.1 - 0.051 13.3 7.9 0.083 12.7 3.7 2.0 1 1 1 2 2 2 0 PBC domain IFT57 PF10498.9 OQR97207.1 - 0.055 12.4 12.1 0.044 12.8 7.9 1.9 1 1 1 2 2 2 0 Intra-flagellar transport protein 57 MCM3AP_GANP PF16769.5 OQR97207.1 - 0.064 11.5 6.6 0.069 11.4 6.6 1.0 1 0 0 1 1 1 0 MCM3AP domain of GANP Nup88 PF10168.9 OQR97207.1 - 0.075 10.8 8.1 0.091 10.6 8.1 1.1 1 0 0 1 1 1 0 Nuclear pore component RmuC PF02646.16 OQR97207.1 - 0.084 12.0 7.6 0.88 8.6 1.7 2.0 1 1 0 2 2 2 0 RmuC family HTH_WhiA PF02650.14 OQR97207.1 - 0.096 13.0 4.2 0.13 12.6 2.5 2.0 1 1 1 2 2 2 0 WhiA C-terminal HTH domain UPF0242 PF06785.11 OQR97207.1 - 0.1 12.7 8.9 0.12 12.5 8.9 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Occludin_ELL PF07303.13 OQR97207.1 - 0.1 13.3 8.5 0.45 11.3 3.3 2.1 1 1 0 1 1 1 0 Occludin homology domain SOAR PF16533.5 OQR97207.1 - 0.18 11.8 7.8 4.4 7.3 7.6 2.4 1 1 0 1 1 1 0 STIM1 Orai1-activating region CPG4 PF15481.6 OQR97207.1 - 0.18 12.4 2.2 0.31 11.7 0.5 2.0 1 1 0 2 2 2 0 Chondroitin proteoglycan 4 ZapB PF06005.12 OQR97207.1 - 0.23 11.9 11.4 0.56 10.7 11.1 1.8 1 1 1 2 2 2 0 Cell division protein ZapB Prominin PF05478.11 OQR97207.1 - 0.23 9.3 6.9 0.28 9.1 6.9 1.0 1 0 0 1 1 1 0 Prominin DUF2564 PF10819.8 OQR97207.1 - 0.42 11.0 8.5 0.23 11.8 3.8 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2564) DUF4298 PF14131.6 OQR97207.1 - 0.59 10.1 7.9 1.3 9.0 3.7 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4298) Spore_III_AB PF09548.10 OQR97207.1 - 0.87 9.7 6.6 1.4 9.0 6.6 1.4 1 1 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) OmpH PF03938.14 OQR97207.1 - 1.5 9.1 13.3 2.1 8.7 13.3 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF948 PF06103.11 OQR97207.1 - 1.6 9.0 5.0 2.5 8.4 1.7 2.1 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) DUF1664 PF07889.12 OQR97207.1 - 1.8 8.6 7.0 4.7 7.3 6.6 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Streptin-Immun PF11083.8 OQR97207.1 - 1.9 8.9 9.6 1.7 9.1 4.6 2.2 1 1 1 2 2 2 0 Lantibiotic streptin immunity protein Fzo_mitofusin PF04799.13 OQR97207.1 - 2.1 7.9 8.7 4 7.0 3.4 2.0 1 1 1 2 2 2 0 fzo-like conserved region XhlA PF10779.9 OQR97207.1 - 2.9 8.2 10.2 1.8 8.8 6.1 2.4 1 1 1 2 2 2 0 Haemolysin XhlA DUF4407 PF14362.6 OQR97207.1 - 3.3 7.0 9.8 4.2 6.6 9.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF724 PF05266.14 OQR97207.1 - 3.3 7.5 11.9 8.9 6.1 3.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF724) V_ATPase_I PF01496.19 OQR97207.1 - 3.4 5.5 10.5 6 4.7 10.5 1.3 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family LMBR1 PF04791.16 OQR97207.1 - 3.8 6.3 5.8 4.3 6.1 5.8 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF349 PF03993.12 OQR97207.1 - 3.8 7.9 10.0 1.9e+02 2.4 9.8 2.4 1 1 0 1 1 1 0 Domain of Unknown Function (DUF349) EMP24_GP25L PF01105.24 OQR97207.1 - 6 6.8 9.1 8.8 6.2 9.1 1.5 1 1 0 1 1 1 0 emp24/gp25L/p24 family/GOLD LtrA PF06772.11 OQR97208.1 - 2.4e-57 194.8 29.3 6.1e-42 144.1 14.9 2.1 2 0 0 2 2 2 2 Bacterial low temperature requirement A protein (LtrA) PP2C_2 PF13672.6 OQR97208.1 - 0.17 11.5 0.0 9.4 5.8 0.0 2.5 2 0 0 2 2 2 0 Protein phosphatase 2C 2OG-FeII_Oxy_2 PF13532.6 OQR97209.1 - 5.6e-20 72.4 0.0 5.4e-19 69.2 0.0 2.3 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Methyltransf_11 PF08241.12 OQR97209.1 - 6.1e-13 49.2 0.1 1.5e-12 48.0 0.1 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OQR97209.1 - 8.5e-10 39.2 0.2 3e-09 37.5 0.1 2.1 2 0 0 2 2 1 1 Methyltransferase domain RRM_1 PF00076.22 OQR97209.1 - 1.6e-06 27.8 0.0 3.6e-06 26.7 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Methyltransf_31 PF13847.6 OQR97209.1 - 1.6e-05 24.7 0.0 4.8e-05 23.2 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 OQR97209.1 - 0.00013 22.6 0.0 0.00033 21.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.11 OQR97209.1 - 0.00024 20.1 0.0 0.0005 19.1 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_8 PF05148.15 OQR97209.1 - 0.00057 19.8 0.0 0.0012 18.7 0.0 1.5 1 0 0 1 1 1 1 Hypothetical methyltransferase RRM_occluded PF16842.5 OQR97209.1 - 0.0023 17.8 0.1 0.0047 16.7 0.1 1.5 1 0 0 1 1 1 1 Occluded RNA-recognition motif RRM_8 PF11835.8 OQR97209.1 - 0.0037 17.4 0.0 0.0083 16.3 0.0 1.5 1 0 0 1 1 1 1 RRM-like domain Methyltransf_23 PF13489.6 OQR97209.1 - 0.0051 16.7 0.0 0.015 15.1 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 OQR97209.1 - 0.027 13.8 0.0 0.1 11.9 0.0 1.8 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family MetW PF07021.12 OQR97209.1 - 0.043 13.4 0.0 0.081 12.5 0.0 1.4 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW DUF4523 PF15023.6 OQR97209.1 - 0.066 13.0 0.1 0.13 12.0 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4523) Rhamnogal_lyase PF06045.11 OQR97209.1 - 0.11 11.8 0.0 0.33 10.3 0.0 1.7 2 0 0 2 2 2 0 Rhamnogalacturonate lyase family PHB_acc PF05233.13 OQR97209.1 - 0.17 11.9 0.4 0.36 10.9 0.4 1.5 1 0 0 1 1 1 0 PHB accumulation regulatory domain Metallophos PF00149.28 OQR97210.1 - 1e-12 49.0 2.7 1.5e-12 48.5 2.7 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Peptidase_U57 PF05582.12 OQR97210.1 - 0.16 11.2 0.0 0.27 10.5 0.0 1.3 1 0 0 1 1 1 0 YabG peptidase U57 DNA_topoisoIV PF00521.20 OQR97211.1 - 7e-127 423.8 0.0 7e-127 423.8 0.0 2.6 2 0 0 2 2 1 1 DNA gyrase/topoisomerase IV, subunit A HI0933_like PF03486.14 OQR97211.1 - 4.1e-89 299.1 0.0 9.1e-89 298.0 0.0 1.5 1 0 0 1 1 1 1 HI0933-like protein TOPRIM_C PF16898.5 OQR97211.1 - 7e-52 175.0 2.6 7e-52 175.0 2.6 2.4 2 0 0 2 2 1 1 C-terminal associated domain of TOPRIM DNA_gyraseB PF00204.25 OQR97211.1 - 8.7e-22 77.4 0.2 2.3e-21 76.1 0.2 1.7 1 0 0 1 1 1 1 DNA gyrase B HATPase_c PF02518.26 OQR97211.1 - 2.7e-13 50.4 0.0 3e-12 47.0 0.0 2.5 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase FAD_binding_2 PF00890.24 OQR97211.1 - 3.1e-07 29.8 1.2 2.5e-06 26.8 1.2 2.1 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 OQR97211.1 - 3.9e-07 29.6 0.3 2.2e-06 27.1 0.3 2.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Toprim PF01751.22 OQR97211.1 - 1.4e-06 28.5 0.0 8.7e-06 25.9 0.0 2.5 1 0 0 1 1 1 1 Toprim domain DAO PF01266.24 OQR97211.1 - 5.4e-06 26.2 3.8 0.012 15.3 0.1 2.7 1 1 1 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 OQR97211.1 - 0.0023 18.1 0.1 0.0054 16.9 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 OQR97211.1 - 0.0027 17.1 0.1 0.0027 17.1 0.1 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Trp_halogenase PF04820.14 OQR97211.1 - 0.009 14.9 0.1 0.016 14.0 0.1 1.4 1 0 0 1 1 1 1 Tryptophan halogenase FAD_binding_3 PF01494.19 OQR97211.1 - 0.061 12.5 1.9 0.16 11.2 1.9 1.7 1 1 0 1 1 1 0 FAD binding domain Thi4 PF01946.17 OQR97211.1 - 0.071 12.3 0.1 0.55 9.4 0.1 2.4 3 0 0 3 3 3 0 Thi4 family NAD_binding_9 PF13454.6 OQR97211.1 - 0.075 13.0 1.3 0.48 10.4 1.3 2.3 1 1 0 1 1 1 0 FAD-NAD(P)-binding Lycopene_cycl PF05834.12 OQR97211.1 - 0.086 11.9 0.7 0.22 10.5 0.1 1.8 2 0 0 2 2 2 0 Lycopene cyclase protein Pyr_redox_3 PF13738.6 OQR97211.1 - 0.15 11.3 9.2 0.48 9.6 0.4 3.4 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 OQR97211.1 - 0.43 11.2 2.6 1.5 9.4 0.2 3.2 3 0 0 3 3 2 0 Pyridine nucleotide-disulphide oxidoreductase Calcyon PF06387.11 OQR97212.1 - 0.068 13.1 0.2 0.068 13.1 0.2 1.7 2 0 0 2 2 2 0 D1 dopamine receptor-interacting protein (calcyon) Hid1 PF12722.7 OQR97212.1 - 8.9 4.3 8.3 9.5 4.2 8.3 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein adh_short PF00106.25 OQR97213.1 - 2.2e-49 167.6 0.2 2.7e-49 167.3 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OQR97213.1 - 6.7e-28 97.8 0.5 9.3e-28 97.4 0.5 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OQR97213.1 - 1.3e-11 44.7 0.2 1.9e-11 44.2 0.2 1.1 1 0 0 1 1 1 1 KR domain THF_DHG_CYH_C PF02882.19 OQR97213.1 - 0.0001 21.7 0.0 0.00018 20.8 0.0 1.3 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain ApbA PF02558.16 OQR97213.1 - 0.035 13.8 0.0 0.056 13.1 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA NAD_binding_7 PF13241.6 OQR97213.1 - 0.13 12.7 0.1 0.22 12.0 0.1 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding Shikimate_DH PF01488.20 OQR97213.1 - 0.15 12.1 0.0 0.32 11.1 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Smg8_Smg9 PF10220.9 OQR97214.1 - 2.7e-05 22.7 0.2 6e-05 21.6 0.0 1.5 2 0 0 2 2 2 1 Smg8_Smg9 MMR_HSR1 PF01926.23 OQR97214.1 - 0.0022 18.0 0.0 0.0044 17.1 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 OQR97214.1 - 0.0067 16.4 0.0 0.023 14.6 0.0 1.8 2 0 0 2 2 2 1 RsgA GTPase ABC_tran PF00005.27 OQR97214.1 - 0.008 16.7 0.0 0.015 15.8 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_18 PF13238.6 OQR97214.1 - 0.078 13.5 0.0 0.18 12.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain MeaB PF03308.16 OQR97214.1 - 0.2 10.6 0.1 0.34 9.8 0.1 1.3 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Pkinase_Tyr PF07714.17 OQR97271.1 - 1.2e-51 175.4 0.0 1.7e-51 175.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OQR97271.1 - 8.5e-51 172.8 0.0 1.4e-50 172.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain LRR_4 PF12799.7 OQR97271.1 - 2e-11 43.9 29.8 5.4e-07 29.8 2.7 4.7 2 2 1 4 4 4 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 OQR97271.1 - 4.4e-09 36.0 24.8 7.6e-05 22.4 6.4 3.6 1 1 1 3 3 3 3 Leucine rich repeat Pkinase_fungal PF17667.1 OQR97271.1 - 6e-06 25.3 0.0 1.1e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 OQR97271.1 - 0.016 14.6 0.0 0.026 13.9 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family LRR_9 PF14580.6 OQR97271.1 - 0.016 14.8 7.0 0.36 10.3 7.0 2.2 1 1 1 2 2 2 0 Leucine-rich repeat LRR_1 PF00560.33 OQR97271.1 - 0.025 15.1 20.6 0.27 11.9 2.2 6.3 5 1 1 6 6 5 0 Leucine Rich Repeat Phage_holin_2_1 PF04971.12 OQR97271.1 - 0.032 14.2 0.1 0.092 12.8 0.1 1.7 1 0 0 1 1 1 0 Bacteriophage P21 holin S Adeno_E3_CR2 PF02439.15 OQR97271.1 - 0.12 12.2 1.0 0.23 11.2 1.0 1.5 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 DUF4199 PF13858.6 OQR97271.1 - 0.13 12.7 0.1 0.22 11.9 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4199) LRR_6 PF13516.6 OQR97271.1 - 0.19 11.9 22.1 0.72 10.1 0.3 6.2 7 0 0 7 7 7 0 Leucine Rich repeat LRR_2 PF07723.13 OQR97271.1 - 0.96 10.2 7.7 90 4.0 0.1 4.6 4 1 1 5 5 5 0 Leucine Rich Repeat PH PF00169.29 OQR97272.1 - 5.3e-66 219.7 11.0 7e-14 52.2 0.0 7.1 7 0 0 7 7 7 6 PH domain PH_11 PF15413.6 OQR97272.1 - 1.6e-25 89.5 27.5 1.4e-05 25.5 0.1 9.4 6 4 0 6 6 6 5 Pleckstrin homology domain PH_8 PF15409.6 OQR97272.1 - 1.6e-20 73.2 15.4 8.5e-05 22.8 0.3 7.6 7 2 1 8 8 8 6 Pleckstrin homology domain PH_3 PF14593.6 OQR97272.1 - 1.1e-14 54.4 0.0 0.00012 22.1 0.0 5.9 4 2 1 5 5 5 3 PH domain Arb2 PF09757.9 OQR97272.1 - 1.7e-13 50.3 0.0 9.3e-06 25.0 0.0 2.3 2 0 0 2 2 2 2 Arb2 domain PH_9 PF15410.6 OQR97272.1 - 0.00016 22.0 11.7 0.89 9.9 0.0 6.5 8 0 0 8 8 8 2 Pleckstrin homology domain DZR PF12773.7 OQR97272.1 - 0.00063 19.7 8.0 0.22 11.6 0.3 2.6 2 0 0 2 2 2 2 Double zinc ribbon zinc_ribbon_15 PF17032.5 OQR97272.1 - 0.17 12.7 3.7 11 6.9 0.4 2.7 2 0 0 2 2 2 0 zinc-ribbon family zinc-ribbons_6 PF07191.12 OQR97272.1 - 1.3 9.1 6.8 7 6.7 0.4 2.5 2 0 0 2 2 2 0 zinc-ribbons PQ-loop PF04193.14 OQR97274.1 - 3e-19 68.6 12.8 2.4e-10 40.0 0.9 3.1 3 0 0 3 3 3 2 PQ loop repeat ABC_tran PF00005.27 OQR97275.1 - 5e-13 49.8 0.0 8e-13 49.1 0.0 1.3 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 OQR97275.1 - 5.5e-06 26.0 0.1 6.8e-06 25.7 0.1 1.1 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain SbcCD_C PF13558.6 OQR97275.1 - 0.00095 19.4 0.2 0.031 14.5 0.2 2.3 1 1 0 1 1 1 1 Putative exonuclease SbcCD, C subunit ABC_tran PF00005.27 OQR97276.1 - 4.8e-44 150.2 0.7 1.7e-21 77.2 0.0 3.0 3 0 0 3 3 3 2 ABC transporter AAA_21 PF13304.6 OQR97276.1 - 2.2e-19 70.4 5.4 0.00038 20.4 0.0 4.4 2 2 2 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system ABC_tran_Xtn PF12848.7 OQR97276.1 - 2.9e-13 49.6 0.2 2.9e-13 49.6 0.2 2.3 2 0 0 2 2 1 1 ABC transporter SMC_N PF02463.19 OQR97276.1 - 1.5e-12 47.4 3.9 0.00053 19.5 1.0 4.6 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 OQR97276.1 - 3.2e-06 27.2 0.0 0.0043 17.1 0.1 3.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_29 PF13555.6 OQR97276.1 - 1.4e-05 24.7 2.0 0.04 13.7 0.2 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 OQR97276.1 - 1.6e-05 24.8 0.4 0.037 13.9 0.1 2.8 2 0 0 2 2 2 2 RsgA GTPase AAA_30 PF13604.6 OQR97276.1 - 2.1e-05 24.3 0.0 0.017 14.9 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_23 PF13476.6 OQR97276.1 - 6.5e-05 23.5 16.1 0.052 14.1 0.2 4.1 4 0 0 4 4 4 2 AAA domain AAA_16 PF13191.6 OQR97276.1 - 0.00011 22.7 0.1 0.79 10.1 0.0 2.7 2 0 0 2 2 2 2 AAA ATPase domain AAA_33 PF13671.6 OQR97276.1 - 0.00032 20.9 0.3 1.1 9.4 0.0 3.1 2 1 0 2 2 2 2 AAA domain AAA_14 PF13173.6 OQR97276.1 - 0.00053 20.0 0.1 0.33 11.0 0.0 3.0 3 0 0 3 3 2 1 AAA domain AAA_18 PF13238.6 OQR97276.1 - 0.002 18.7 6.4 0.33 11.5 0.1 3.8 4 1 1 5 5 4 2 AAA domain NACHT PF05729.12 OQR97276.1 - 0.0031 17.4 0.1 2.7 7.9 0.0 2.6 2 0 0 2 2 2 1 NACHT domain AAA_15 PF13175.6 OQR97276.1 - 0.0083 15.9 7.0 0.4 10.3 0.1 4.1 4 1 0 4 4 4 1 AAA ATPase domain MeaB PF03308.16 OQR97276.1 - 0.0087 15.1 2.9 0.1 11.6 0.0 2.7 3 0 0 3 3 3 1 Methylmalonyl Co-A mutase-associated GTPase MeaB cobW PF02492.19 OQR97276.1 - 0.011 15.3 0.2 3.3 7.2 0.1 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_28 PF13521.6 OQR97276.1 - 0.012 15.9 1.2 1.1 9.5 0.0 2.9 3 0 0 3 3 2 0 AAA domain NB-ARC PF00931.22 OQR97276.1 - 0.012 14.8 0.1 3.6 6.7 0.1 2.5 2 0 0 2 2 2 0 NB-ARC domain SbcCD_C PF13558.6 OQR97276.1 - 0.019 15.2 0.1 3.3 8.0 0.1 3.5 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_24 PF13479.6 OQR97276.1 - 0.02 14.6 3.8 3.6 7.3 0.2 3.5 2 1 1 3 3 3 0 AAA domain DUF87 PF01935.17 OQR97276.1 - 0.025 14.7 6.6 0.036 14.2 0.1 3.2 3 0 0 3 3 3 0 Helicase HerA, central domain AAA PF00004.29 OQR97276.1 - 0.029 14.8 0.0 15 6.0 0.0 2.9 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Thymidylate_kin PF02223.17 OQR97276.1 - 0.031 14.0 0.0 1.4 8.6 0.0 3.1 2 0 0 2 2 2 0 Thymidylate kinase Viral_helicase1 PF01443.18 OQR97276.1 - 0.054 13.2 0.0 0.76 9.5 0.0 2.4 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase RNA_helicase PF00910.22 OQR97276.1 - 0.063 13.7 0.1 9.9 6.6 0.0 3.3 3 0 0 3 3 3 0 RNA helicase MobB PF03205.14 OQR97276.1 - 0.067 13.1 0.3 13 5.7 0.1 2.9 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Roc PF08477.13 OQR97276.1 - 0.075 13.3 0.1 11 6.3 0.0 2.8 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase NTPase_1 PF03266.15 OQR97276.1 - 0.08 12.9 0.7 4.6 7.1 0.2 3.0 3 0 0 3 3 2 0 NTPase Arf PF00025.21 OQR97276.1 - 0.1 12.1 0.6 9.1 5.7 0.0 3.0 2 1 1 3 3 3 0 ADP-ribosylation factor family KAP_NTPase PF07693.14 OQR97276.1 - 0.15 11.3 1.7 10 5.2 0.0 3.0 3 1 1 4 4 4 0 KAP family P-loop domain AAA_22 PF13401.6 OQR97276.1 - 0.16 12.3 6.5 5.5 7.3 0.1 3.6 4 2 0 4 4 3 0 AAA domain AAA_13 PF13166.6 OQR97276.1 - 0.16 10.6 9.9 0.49 9.0 0.0 3.2 3 0 0 3 3 3 0 AAA domain TsaE PF02367.17 OQR97276.1 - 0.16 11.9 0.3 8.1 6.5 0.1 2.6 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE PduV-EutP PF10662.9 OQR97276.1 - 0.17 11.6 1.2 4.4 7.0 0.0 3.0 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation ATP_bind_1 PF03029.17 OQR97276.1 - 0.24 11.2 1.4 28 4.4 0.1 3.4 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein Dynamin_N PF00350.23 OQR97276.1 - 0.51 10.4 0.0 0.51 10.4 0.0 3.0 3 1 0 3 3 2 0 Dynamin family AAA_5 PF07728.14 OQR97276.1 - 0.81 9.7 2.7 40 4.2 0.1 3.4 4 1 0 4 4 2 0 AAA domain (dynein-related subfamily) SRP54 PF00448.22 OQR97276.1 - 0.94 9.1 3.8 23 4.6 0.0 3.1 3 0 0 3 3 3 0 SRP54-type protein, GTPase domain AAA_17 PF13207.6 OQR97276.1 - 1.3 9.5 6.5 17 5.9 0.1 3.7 3 1 0 3 3 3 0 AAA domain COX16 PF14138.6 OQR97276.1 - 9.7 6.8 11.2 18 6.0 4.9 3.2 2 2 0 2 2 2 0 Cytochrome c oxidase assembly protein COX16 Patched PF02460.18 OQR97277.1 - 5.1e-64 216.7 38.5 2.2e-42 145.2 10.1 3.1 2 1 1 3 3 3 2 Patched family Sterol-sensing PF12349.8 OQR97277.1 - 1.7e-34 118.9 8.9 1.7e-34 118.9 8.9 2.7 2 0 0 2 2 2 1 Sterol-sensing domain of SREBP cleavage-activation NPC1_N PF16414.5 OQR97277.1 - 6.9e-13 48.7 10.0 1.9e-12 47.3 10.0 1.7 1 0 0 1 1 1 1 Niemann-Pick C1 N terminus Bac_DnaA_C PF08299.11 OQR97277.1 - 0.061 13.4 0.0 0.15 12.1 0.0 1.6 1 0 0 1 1 1 0 Bacterial dnaA protein helix-turn-helix MMPL PF03176.15 OQR97277.1 - 1.8 7.4 25.6 0.063 12.2 3.0 3.0 3 0 0 3 3 3 0 MMPL family YecM PF06185.12 OQR97278.1 - 6.7e-25 87.8 0.0 3.8e-24 85.3 0.0 1.8 1 1 0 1 1 1 1 YecM protein DGF-1_C PF11040.8 OQR97279.1 - 0.88 9.6 7.7 1 9.4 0.5 2.8 2 1 1 3 3 3 0 Dispersed gene family protein 1 of Trypanosoma cruzi C-terminus Mis12 PF05859.12 OQR97279.1 - 2.7 8.0 7.7 43 4.2 7.7 2.3 1 1 0 1 1 1 0 Mis12 protein Dimer_Tnp_hAT PF05699.14 OQR97282.1 - 0.00013 21.7 0.1 0.00078 19.2 0.0 2.3 2 0 0 2 2 2 1 hAT family C-terminal dimerisation region zf-H2C2_5 PF13909.6 OQR97282.1 - 5.2 6.9 13.5 3.2 7.6 3.1 2.9 2 0 0 2 2 2 0 C2H2-type zinc-finger domain PGM_PMM_I PF02878.16 OQR97283.1 - 2.4e-17 62.9 1.6 1.1e-07 31.6 0.0 3.6 3 1 1 4 4 4 2 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_IV PF00408.20 OQR97283.1 - 1.8e-09 37.6 2.4 3.2e-09 36.8 1.2 2.1 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain PGM_PMM_III PF02880.16 OQR97283.1 - 2.7e-07 30.8 0.1 7.1e-07 29.4 0.1 1.9 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.16 OQR97283.1 - 0.0014 19.2 0.1 0.0056 17.3 0.1 2.1 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II DUF1856 PF08983.10 OQR97284.1 - 7.7 6.8 8.6 0.39 11.0 0.5 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF1856) SNase PF00565.17 OQR97285.1 - 1.2e-24 86.9 0.0 1.5e-24 86.5 0.0 1.2 1 0 0 1 1 1 1 Staphylococcal nuclease homologue CEBP_ZZ PF16366.5 OQR97287.1 - 1.3e-10 41.4 55.6 0.0065 16.7 13.4 4.6 4 0 0 4 4 4 4 Cytoplasmic polyadenylation element-binding protein ZZ domain WW PF00397.26 OQR97287.1 - 9.6e-09 35.2 12.3 0.0006 19.9 1.8 3.8 3 1 0 3 3 3 3 WW domain zf-B_box PF00643.24 OQR97287.1 - 0.00033 20.7 65.2 0.063 13.4 4.7 4.9 5 0 0 5 5 5 4 B-box zinc finger PQQ PF01011.21 OQR97287.1 - 0.071 13.1 0.0 1.3 9.1 0.0 2.4 2 0 0 2 2 2 0 PQQ enzyme repeat IQ PF00612.27 OQR97287.1 - 0.072 12.9 34.7 1.2 9.2 1.5 5.8 5 0 0 5 5 5 0 IQ calmodulin-binding motif Ank_2 PF12796.7 OQR97289.1 - 4.1e-31 107.4 5.0 3.6e-09 37.1 0.2 6.5 4 2 1 6 6 6 5 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OQR97289.1 - 5.7e-23 80.7 9.9 3.5e-06 27.2 0.1 8.7 6 3 3 9 9 9 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQR97289.1 - 3.3e-20 70.0 14.5 0.1 13.2 0.0 12.0 13 0 0 13 13 13 5 Ankyrin repeat Ank_4 PF13637.6 OQR97289.1 - 5.4e-19 68.3 3.7 6.1e-05 23.5 0.1 8.1 6 2 2 8 8 8 5 Ankyrin repeats (many copies) Ank PF00023.30 OQR97289.1 - 1.8e-18 66.1 15.6 0.44 11.1 0.0 11.2 13 0 0 13 13 13 6 Ankyrin repeat PH PF00169.29 OQR97289.1 - 0.018 15.6 0.9 0.064 13.8 0.0 2.4 2 0 0 2 2 2 0 PH domain DUF737 PF05300.11 OQR97289.1 - 2.6 8.3 10.3 3.4 8.0 8.7 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF737) Glyco_transf_22 PF03901.17 OQR97301.1 - 1.5e-84 284.6 30.1 1.9e-84 284.3 30.1 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family UQ_con PF00179.26 OQR97301.1 - 2e-12 47.0 0.1 3.9e-12 46.0 0.1 1.5 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UME PF08064.13 OQR97303.1 - 0.0056 16.6 1.8 0.011 15.7 1.9 1.5 1 1 0 1 1 1 1 UME (NUC010) domain DUF5485 PF17586.2 OQR97303.1 - 0.063 13.6 0.0 0.13 12.6 0.0 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5485) I_LWEQ PF01608.17 OQR97303.1 - 0.08 13.2 1.6 0.11 12.7 1.6 1.1 1 0 0 1 1 1 0 I/LWEQ domain TLD PF07534.16 OQR97305.1 - 5.1e-31 107.8 0.0 1e-30 106.7 0.0 1.6 1 0 0 1 1 1 1 TLD DUF1338 PF07063.13 OQR97305.1 - 0.092 11.9 0.1 0.14 11.3 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1338) Taxilin PF09728.9 OQR97306.1 - 1.3 8.1 32.2 3 6.9 32.2 1.5 1 0 0 1 1 1 0 Myosin-like coiled-coil protein WD40 PF00400.32 OQR97307.1 - 1.5e-10 41.5 6.1 0.046 14.6 0.0 6.1 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OQR97307.1 - 0.00032 21.0 0.0 0.043 14.1 0.0 3.4 2 1 1 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 OQR97307.1 - 0.15 12.1 0.1 0.48 10.4 0.1 1.9 1 0 0 1 1 1 0 WD40-like Beta Propeller Repeat Ank_5 PF13857.6 OQR97308.1 - 4.3e-17 61.9 0.1 2.1e-11 43.8 0.1 3.4 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 OQR97308.1 - 2.5e-15 56.8 0.0 3.9e-15 56.2 0.0 1.3 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQR97308.1 - 2.3e-13 50.3 0.4 1.5e-10 41.3 0.1 2.4 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQR97308.1 - 5.7e-13 47.8 0.2 6.2e-06 26.2 0.1 3.5 3 0 0 3 3 3 2 Ankyrin repeat Ank PF00023.30 OQR97308.1 - 9.4e-12 44.8 0.4 1.1e-07 31.9 0.2 2.6 2 0 0 2 2 2 2 Ankyrin repeat BT1 PF03092.16 OQR97309.1 - 3.2e-12 45.5 0.4 4.7e-12 44.9 0.4 1.2 1 0 0 1 1 1 1 BT1 family PUCC PF03209.15 OQR97309.1 - 5.1e-05 22.4 0.2 0.00011 21.4 0.1 1.5 2 0 0 2 2 2 1 PUCC protein MFS_1 PF07690.16 OQR97309.1 - 0.00045 19.2 8.6 0.0007 18.6 8.7 1.2 1 1 0 1 1 1 1 Major Facilitator Superfamily BT1 PF03092.16 OQR97310.1 - 2.1e-11 42.7 0.7 2.1e-11 42.7 0.7 4.5 3 2 0 5 5 5 3 BT1 family PUCC PF03209.15 OQR97310.1 - 6e-05 22.2 3.6 6e-05 22.2 3.6 2.8 2 1 0 2 2 2 1 PUCC protein Nup96 PF12110.8 OQR97311.1 - 3e-42 144.7 9.0 5.2e-42 144.0 9.0 1.4 1 0 0 1 1 1 1 Nuclear protein 96 Nucleoporin2 PF04096.14 OQR97311.1 - 3.2e-37 127.9 0.0 5.9e-37 127.1 0.0 1.5 1 0 0 1 1 1 1 Nucleoporin autopeptidase SAM_3 PF18016.1 OQR97311.1 - 0.15 11.9 0.0 0.34 10.7 0.0 1.6 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) Clathrin PF00637.20 OQR97311.1 - 0.23 11.3 0.8 20 5.0 0.3 3.2 3 1 0 3 3 3 0 Region in Clathrin and VPS DUF2827 PF10933.8 OQR97314.1 - 0.13 10.9 0.0 0.16 10.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2827) HAD PF12710.7 OQR97316.1 - 0.01 16.3 0.0 0.02 15.3 0.0 1.5 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 OQR97316.1 - 0.016 15.5 0.0 0.033 14.5 0.0 1.5 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase ICMT PF04140.14 OQR97341.1 - 5.3e-29 100.5 0.1 5.3e-29 100.5 0.1 1.9 2 1 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 OQR97341.1 - 1.5e-08 35.0 0.4 1.5e-08 35.0 0.4 2.2 2 0 0 2 2 2 1 Phospholipid methyltransferase DUF1295 PF06966.12 OQR97341.1 - 0.00025 20.6 1.3 0.00025 20.6 1.3 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1295) LapA_dom PF06305.11 OQR97341.1 - 0.24 11.2 4.5 0.28 11.0 0.9 2.5 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain Glu_cyclase_2 PF05096.12 OQR97342.1 - 2e-73 247.0 0.2 2.3e-73 246.7 0.2 1.0 1 0 0 1 1 1 1 Glutamine cyclotransferase PQQ_2 PF13360.6 OQR97342.1 - 0.0069 16.0 0.1 0.014 15.0 0.1 1.5 1 1 0 1 1 1 1 PQQ-like domain Arylesterase PF01731.20 OQR97342.1 - 0.11 12.8 0.2 0.26 11.5 0.2 1.7 1 0 0 1 1 1 0 Arylesterase NHL PF01436.21 OQR97342.1 - 3.4 7.9 8.1 42 4.4 0.0 4.3 4 1 1 5 5 5 0 NHL repeat Toprim PF01751.22 OQR97343.1 - 0.0043 17.2 0.1 0.005 17.0 0.1 1.1 1 0 0 1 1 1 1 Toprim domain Toprim_4 PF13662.6 OQR97343.1 - 0.15 12.6 0.0 0.17 12.4 0.0 1.2 1 0 0 1 1 1 0 Toprim domain Abhydrolase_4 PF08386.10 OQR97344.1 - 0.00042 20.4 0.0 0.00076 19.6 0.0 1.5 1 0 0 1 1 1 1 TAP-like protein Sel1 PF08238.12 OQR97345.1 - 1.9e-45 152.3 23.4 1.8e-08 34.8 0.5 6.7 7 0 0 7 7 7 6 Sel1 repeat Tai4 PF16695.5 OQR97345.1 - 0.078 13.5 0.6 3.8 8.1 0.1 3.0 2 1 0 2 2 2 0 Type VI secretion system (T6SS), amidase immunity protein DIOX_N PF14226.6 OQR97345.1 - 0.089 13.5 0.5 40 5.0 0.0 3.2 2 1 1 3 3 3 0 non-haem dioxygenase in morphine synthesis N-terminal TPR_14 PF13428.6 OQR97345.1 - 0.11 13.3 4.3 2.9 8.9 0.1 3.8 4 1 0 4 4 4 0 Tetratricopeptide repeat CD20 PF04103.15 OQR97346.1 - 0.002 18.2 0.0 0.0029 17.7 0.0 1.1 1 0 0 1 1 1 1 CD20-like family Orf78 PF06024.12 OQR97346.1 - 0.13 12.5 0.0 0.23 11.8 0.0 1.4 1 1 0 1 1 1 0 Orf78 (ac78) Glu-tRNAGln PF02686.15 OQR97348.1 - 1.5e-08 34.8 0.0 2.6e-08 34.0 0.0 1.4 1 0 0 1 1 1 1 Glu-tRNAGln amidotransferase C subunit Phosducin PF02114.16 OQR97349.1 - 3.8e-14 52.3 0.0 4.6e-14 52.0 0.0 1.0 1 0 0 1 1 1 1 Phosducin Thioredoxin PF00085.20 OQR97349.1 - 0.0049 16.8 0.0 0.0078 16.2 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin EF-1_beta_acid PF10587.9 OQR97349.1 - 3 8.4 12.2 0.16 12.5 4.2 2.4 2 0 0 2 2 2 0 Eukaryotic elongation factor 1 beta central acidic region TFIIB PF00382.19 OQR97350.1 - 2.5e-29 101.1 0.2 1.9e-13 50.3 0.0 2.6 2 0 0 2 2 2 2 Transcription factor TFIIB repeat BRF1 PF07741.13 OQR97350.1 - 5e-20 71.7 4.8 5e-20 71.7 4.8 1.7 2 0 0 2 2 2 1 Brf1-like TBP-binding domain TF_Zn_Ribbon PF08271.12 OQR97350.1 - 4.1e-07 29.4 3.7 8.2e-07 28.4 3.7 1.6 1 0 0 1 1 1 1 TFIIB zinc-binding zf-RRN7 PF11781.8 OQR97350.1 - 0.00072 19.2 1.0 0.0017 18.0 1.0 1.7 1 0 0 1 1 1 1 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 Auto_anti-p27 PF06677.12 OQR97350.1 - 2.4 8.4 4.4 4.9 7.4 4.4 1.6 1 0 0 1 1 1 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) RNA_polI_A34 PF08208.11 OQR97351.1 - 6.4e-11 42.7 0.2 6.4e-11 42.7 0.2 2.0 1 1 1 2 2 2 1 DNA-directed RNA polymerase I subunit RPA34.5 TAFII55_N PF04658.13 OQR97351.1 - 0.00082 19.1 0.4 0.00092 19.0 0.4 1.1 1 0 0 1 1 1 1 TAFII55 protein conserved region FAM177 PF14774.6 OQR97352.1 - 4e-06 27.2 0.2 6e-06 26.6 0.1 1.4 1 1 0 1 1 1 1 FAM177 family Histone_HNS PF00816.21 OQR97352.1 - 0.43 11.4 8.1 0.65 10.9 8.1 1.2 1 0 0 1 1 1 0 H-NS histone family Mcl1_mid PF12341.8 OQR97353.1 - 2.1e-50 171.8 0.0 8.7e-49 166.5 0.0 2.6 3 0 0 3 3 3 1 Minichromosome loss protein, Mcl1, middle region Ribosomal_L5_C PF00673.21 OQR97353.1 - 7.6e-23 80.5 0.0 1.6e-21 76.3 0.0 2.7 2 0 0 2 2 2 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.19 OQR97353.1 - 8.7e-22 77.2 0.0 1.8e-21 76.2 0.0 1.6 1 0 0 1 1 1 1 Ribosomal protein L5 WD40 PF00400.32 OQR97353.1 - 1.6e-08 35.1 0.0 0.044 14.7 0.0 4.1 3 0 0 3 3 3 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OQR97353.1 - 2.9e-07 30.7 0.1 0.0069 16.7 0.0 3.9 2 1 2 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain HTH_ABP1_N PF18107.1 OQR97353.1 - 0.029 14.1 0.2 0.071 12.8 0.2 1.6 1 0 0 1 1 1 0 Fission yeast centromere protein N-terminal domain SurE PF01975.17 OQR97353.1 - 0.059 13.1 0.4 0.18 11.5 0.4 1.8 1 0 0 1 1 1 0 Survival protein SurE GRIM-19 PF06212.12 OQR97354.1 - 7.7e-30 103.5 0.2 9.3e-30 103.3 0.2 1.0 1 0 0 1 1 1 1 GRIM-19 protein RRM_1 PF00076.22 OQR97355.1 - 1.4e-17 63.2 0.0 2.6e-17 62.4 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4972 PF16342.5 OQR97355.1 - 0.43 10.3 2.6 0.95 9.2 2.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4972) DUF5305 PF17231.2 OQR97356.1 - 0.039 13.4 0.2 0.071 12.5 0.2 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5305) DUF4366 PF14283.6 OQR97356.1 - 0.064 13.3 0.2 0.064 13.3 0.2 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4366) CD99L2 PF12301.8 OQR97356.1 - 0.069 13.4 10.3 0.14 12.4 10.3 1.6 1 1 0 1 1 1 0 CD99 antigen like protein 2 SCF PF02404.15 OQR97356.1 - 0.1 11.9 0.1 0.1 11.9 0.1 1.4 2 0 0 2 2 2 0 Stem cell factor DUF2613 PF11021.8 OQR97356.1 - 0.13 12.4 3.4 1 9.5 0.1 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2613) TMEM51 PF15345.6 OQR97356.1 - 0.38 10.5 3.8 0.57 10.0 0.1 2.2 2 0 0 2 2 2 0 Transmembrane protein 51 SPX PF03105.19 OQR97356.1 - 0.89 9.4 6.3 1.2 9.0 6.3 1.2 1 0 0 1 1 1 0 SPX domain AhpC-TSA PF00578.21 OQR97357.1 - 1.1e-25 90.0 0.0 1.4e-25 89.6 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 OQR97357.1 - 2e-16 60.0 0.2 2.5e-16 59.7 0.2 1.1 1 0 0 1 1 1 1 Redoxin AhpC-TSA_2 PF13911.6 OQR97357.1 - 0.012 15.7 0.0 0.02 15.0 0.0 1.3 1 0 0 1 1 1 0 AhpC/TSA antioxidant enzyme Histone_H2A_C PF16211.5 OQR97357.1 - 0.085 12.6 0.1 0.2 11.4 0.1 1.6 1 0 0 1 1 1 0 C-terminus of histone H2A HABP4_PAI-RBP1 PF04774.15 OQR97364.1 - 6.5e-13 49.6 13.3 6.5e-13 49.6 13.3 3.3 3 2 1 4 4 4 1 Hyaluronan / mRNA binding family Stm1_N PF09598.10 OQR97364.1 - 0.0028 18.5 9.2 0.0028 18.5 9.2 3.8 3 1 1 4 4 4 1 Stm1 MatE PF01554.18 OQR97365.1 - 5.5e-55 185.4 53.6 1.5e-23 83.3 15.6 3.8 4 0 0 4 4 4 3 MatE TBP PF00352.21 OQR97365.1 - 0.0047 16.8 0.0 0.49 10.4 0.0 2.6 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DJ-1_PfpI PF01965.24 OQR97366.1 - 1.8e-21 76.6 0.0 2.1e-21 76.4 0.0 1.0 1 0 0 1 1 1 1 DJ-1/PfpI family MORN PF02493.20 OQR97367.1 - 1.4e-40 134.7 51.2 2.1e-06 27.3 1.1 11.1 11 0 0 11 11 11 10 MORN repeat Linker_histone PF00538.19 OQR97367.1 - 0.16 12.4 0.2 0.37 11.2 0.2 1.6 1 0 0 1 1 1 0 linker histone H1 and H5 family MatE PF01554.18 OQR97368.1 - 0.00054 19.7 5.7 0.00054 19.7 5.7 1.4 2 0 0 2 2 2 1 MatE Peptidase_C50 PF03568.17 OQR97373.1 - 8e-61 206.3 0.3 1.4e-49 169.3 0.0 2.2 2 0 0 2 2 2 2 Peptidase family C50 TPR_2 PF07719.17 OQR97373.1 - 1.1e-05 25.1 0.4 1.8 8.9 0.2 4.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 OQR97373.1 - 0.00016 22.1 2.4 0.95 10.0 0.4 3.6 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 OQR97373.1 - 0.0015 19.2 0.1 1.2 10.1 0.0 4.5 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.6 OQR97373.1 - 0.002 18.4 2.3 6.1 7.2 0.2 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.28 OQR97373.1 - 0.0023 17.7 0.1 0.75 9.7 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat CHAT PF12770.7 OQR97373.1 - 0.0025 17.3 0.0 0.0051 16.3 0.0 1.4 1 0 0 1 1 1 1 CHAT domain TPR_20 PF14561.6 OQR97373.1 - 0.005 17.1 0.1 0.022 15.1 0.0 2.1 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 OQR97373.1 - 0.0063 16.6 2.3 2.8 8.4 0.0 4.3 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_10 PF13374.6 OQR97373.1 - 0.065 13.1 0.0 2.8 7.9 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.6 OQR97373.1 - 0.067 13.3 0.3 29 5.0 0.0 3.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_11 PF13414.6 OQR97373.1 - 0.13 12.0 0.5 4.7 7.0 0.0 3.3 3 0 0 3 3 3 0 TPR repeat DUF4363 PF14276.6 OQR97373.1 - 3.2 7.9 6.9 0.47 10.6 0.9 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4363) DUF995 PF06191.12 OQR97374.1 - 0.2 11.4 2.2 0.4 10.4 2.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF995) zf-RING_11 PF17123.5 OQR97375.1 - 0.00038 20.2 1.0 0.00085 19.0 1.0 1.6 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_2 PF13639.6 OQR97375.1 - 0.002 18.4 7.2 0.0037 17.6 7.2 1.5 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 OQR97375.1 - 0.0045 17.3 4.3 0.011 16.0 4.3 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 OQR97375.1 - 0.0061 16.6 7.3 0.017 15.1 7.3 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 OQR97375.1 - 0.015 15.3 4.7 0.034 14.1 4.6 1.6 1 1 0 1 1 1 0 zinc-RING finger domain zf-ANAPC11 PF12861.7 OQR97375.1 - 0.056 13.5 2.3 0.14 12.2 2.3 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_2 PF13923.6 OQR97375.1 - 0.12 12.3 7.2 0.29 11.0 7.2 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 OQR97375.1 - 0.15 12.0 3.5 0.33 10.8 3.5 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 OQR97375.1 - 0.16 11.8 2.9 0.27 11.1 2.9 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Zn-ribbon_8 PF09723.10 OQR97375.1 - 0.44 10.7 3.4 0.21 11.8 0.4 2.1 2 0 0 2 2 2 0 Zinc ribbon domain zf-C3HC4 PF00097.25 OQR97375.1 - 0.61 10.0 5.4 1.6 8.7 5.4 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DNA_primase_lrg PF04104.14 OQR97376.1 - 2.1e-53 181.5 1.5 2.6e-53 181.1 1.5 1.1 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase, large subunit ADH_N PF08240.12 OQR97377.1 - 8.2e-26 90.0 2.4 1.7e-25 89.0 2.4 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 OQR97377.1 - 7.5e-24 84.2 0.2 1.4e-23 83.3 0.2 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 OQR97377.1 - 0.0019 17.6 0.1 0.0032 16.8 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.14 OQR97377.1 - 0.005 16.4 0.2 0.008 15.8 0.2 1.3 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain ADH_zinc_N_2 PF13602.6 OQR97377.1 - 0.0063 17.6 0.0 0.015 16.4 0.0 1.6 1 1 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 OQR97377.1 - 0.044 13.1 0.6 0.075 12.3 0.6 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain RET_CLD3 PF17812.1 OQR97377.1 - 0.2 11.9 0.0 0.36 11.1 0.0 1.4 1 0 0 1 1 1 0 RET Cadherin like domain 3 Mic1 PF07035.12 OQR97378.1 - 0.071 12.8 0.2 0.45 10.2 0.1 2.2 2 0 0 2 2 2 0 Colon cancer-associated protein Mic1-like TPR_16 PF13432.6 OQR97378.1 - 0.11 13.2 3.5 34 5.2 0.1 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_19 PF14559.6 OQR97378.1 - 0.46 11.0 6.7 15 6.2 0.2 4.1 4 1 0 4 4 4 0 Tetratricopeptide repeat Alkyl_sulf_dimr PF14863.6 OQR97378.1 - 0.48 10.9 2.1 45 4.5 0.0 3.5 3 1 1 4 4 4 0 Alkyl sulfatase dimerisation TPR_14 PF13428.6 OQR97378.1 - 0.94 10.5 6.0 32 5.7 0.1 4.5 5 0 0 5 5 5 0 Tetratricopeptide repeat Zn-ribbon_8 PF09723.10 OQR97379.1 - 0.13 12.4 0.9 0.28 11.3 0.9 1.6 1 0 0 1 1 1 0 Zinc ribbon domain AFT PF08731.11 OQR97384.1 - 0.018 15.4 1.6 0.039 14.3 1.6 1.7 1 1 0 1 1 1 0 Transcription factor AFT zf-MYND PF01753.18 OQR97385.1 - 6.8e-09 35.7 11.1 1.4e-08 34.6 11.1 1.6 1 0 0 1 1 1 1 MYND finger zf-C6H2 PF15801.5 OQR97385.1 - 0.0021 18.3 9.4 0.0043 17.3 9.4 1.4 1 0 0 1 1 1 1 zf-MYND-like zinc finger, mRNA-binding Rhodanese_C PF12368.8 OQR97385.1 - 0.069 13.5 4.8 0.11 12.8 4.8 1.3 1 0 0 1 1 1 0 Rhodanase C-terminal Cyt-b5 PF00173.28 OQR97386.1 - 1.4e-06 28.4 0.0 2.8e-06 27.4 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain RCC1 PF00415.18 OQR97388.1 - 1.1e-66 221.3 27.1 4.1e-14 52.9 0.2 7.8 7 1 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 OQR97388.1 - 6.2e-26 89.6 34.8 2e-07 30.6 0.0 7.7 8 0 0 8 8 8 6 Regulator of chromosome condensation (RCC1) repeat Chorion_1 PF01723.16 OQR97388.1 - 0.064 13.2 8.8 0.18 11.8 0.1 2.3 2 0 0 2 2 2 0 Chorion protein IQ PF00612.27 OQR97388.1 - 0.073 12.9 3.6 0.1 12.5 0.1 2.8 2 0 0 2 2 2 0 IQ calmodulin-binding motif COMM_domain PF07258.14 OQR97389.1 - 6.1e-08 32.7 0.5 1.5e-07 31.4 0.5 1.7 1 1 0 1 1 1 1 COMM domain Thioredoxin PF00085.20 OQR97390.1 - 3.2e-09 36.7 0.0 1.2e-08 34.8 0.0 2.0 2 0 0 2 2 2 1 Thioredoxin Cwf_Cwc_15 PF04889.12 OQR97390.1 - 0.55 9.9 14.3 0.96 9.1 14.3 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Tub PF01167.18 OQR97391.1 - 3.1e-25 89.3 0.1 1.7e-24 86.9 0.0 1.8 2 0 0 2 2 2 1 Tub family DTHCT PF08070.11 OQR97391.1 - 0.0067 17.1 4.0 0.011 16.5 4.0 1.4 1 0 0 1 1 1 1 DTHCT (NUC029) region DUF4614 PF15391.6 OQR97391.1 - 0.022 14.8 0.6 0.042 13.8 0.3 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4614) Peptidase_M1 PF01433.20 OQR97392.1 - 2.1e-50 171.3 1.1 3.2e-50 170.7 1.1 1.3 1 0 0 1 1 1 1 Peptidase family M1 domain Leuk-A4-hydro_C PF09127.11 OQR97392.1 - 2.8e-36 124.0 0.4 6.3e-36 122.9 0.4 1.6 1 0 0 1 1 1 1 Leukotriene A4 hydrolase, C-terminal Peptidase_M1_N PF17900.1 OQR97392.1 - 2.2e-22 80.2 0.0 3.7e-22 79.4 0.0 1.3 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain Peptidase_M48 PF01435.18 OQR97392.1 - 0.098 12.4 0.0 2.5 7.8 0.0 2.3 2 0 0 2 2 2 0 Peptidase family M48 Peptidase_MA_2 PF13485.6 OQR97392.1 - 0.24 11.0 1.1 0.73 9.5 1.1 1.8 1 1 0 1 1 1 0 Peptidase MA superfamily DUF5582 PF17819.1 OQR97393.1 - 0.0073 16.8 0.3 0.024 15.1 0.1 2.0 2 0 0 2 2 2 1 Family of unknown function (DUF5582) PAR1 PF06521.11 OQR97393.1 - 0.0079 15.8 0.0 0.02 14.5 0.0 1.6 1 0 0 1 1 1 1 PAR1 protein EF-hand_14 PF17959.1 OQR97393.1 - 0.014 15.7 0.2 0.095 13.1 0.0 2.4 2 0 0 2 2 2 0 EF-hand domain T2SSM PF04612.12 OQR97393.1 - 0.032 14.3 6.0 0.06 13.4 6.0 1.4 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein M EF-hand_7 PF13499.6 OQR97393.1 - 0.049 14.1 0.0 0.16 12.4 0.0 1.9 1 0 0 1 1 1 0 EF-hand domain pair EF-hand_6 PF13405.6 OQR97393.1 - 0.054 13.4 0.1 0.16 12.0 0.1 1.8 1 0 0 1 1 1 0 EF-hand domain EF-hand_8 PF13833.6 OQR97393.1 - 0.058 13.2 0.3 0.63 9.9 0.0 2.3 2 0 0 2 2 2 0 EF-hand domain pair EF-hand_1 PF00036.32 OQR97393.1 - 0.069 12.7 0.0 0.2 11.3 0.0 1.9 1 0 0 1 1 1 0 EF hand Surfac_D-trimer PF09006.11 OQR97393.1 - 0.09 12.7 0.2 0.2 11.6 0.2 1.6 1 0 0 1 1 1 0 Lung surfactant protein D coiled-coil trimerisation Flavokinase PF01687.17 OQR97393.1 - 0.11 12.8 0.0 0.4 11.0 0.0 1.8 2 0 0 2 2 2 0 Riboflavin kinase DUF5320 PF17253.2 OQR97393.1 - 0.39 11.8 0.1 0.39 11.8 0.1 2.2 3 0 0 3 3 2 0 Family of unknown function (DUF5320) bZIP_C PF12498.8 OQR97395.1 - 0.027 15.5 0.5 0.027 15.5 0.5 1.9 2 1 0 2 2 2 0 Basic leucine-zipper C terminal DUF919 PF06034.11 OQR97395.1 - 0.1 12.4 1.2 0.25 11.2 0.5 2.1 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF919) Geminin PF07412.12 OQR97396.1 - 4.6e-05 23.3 13.4 0.14 11.8 0.8 3.3 3 0 0 3 3 3 3 Geminin DUF2357 PF09823.9 OQR97396.1 - 3.4 6.8 8.9 0.97 8.6 0.9 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF2357) DivIC PF04977.15 OQR97398.1 - 0.074 12.8 1.0 0.19 11.5 1.0 1.7 1 0 0 1 1 1 0 Septum formation initiator IATP PF04568.12 OQR97399.1 - 0.28 11.6 1.3 0.38 11.2 0.8 1.4 2 0 0 2 2 2 0 Mitochondrial ATPase inhibitor, IATP Period_C PF12114.8 OQR97400.1 - 0.18 11.4 1.5 0.28 10.8 1.5 1.3 1 0 0 1 1 1 0 Period protein 2/3C-terminal region bZIP_1 PF00170.21 OQR97400.1 - 0.4 10.8 14.2 0.1 12.7 4.6 2.5 1 1 1 2 2 2 0 bZIP transcription factor FlgN PF05130.12 OQR97400.1 - 0.42 11.1 8.7 0.74 10.3 8.7 1.3 1 0 0 1 1 1 0 FlgN protein UPF0242 PF06785.11 OQR97400.1 - 0.85 9.7 10.2 1.5 8.8 10.2 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Fib_alpha PF08702.10 OQR97400.1 - 1.7 8.8 6.0 3.3 7.9 6.0 1.5 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family OmpH PF03938.14 OQR97400.1 - 2 8.7 12.9 0.45 10.9 8.7 1.8 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) bZIP_2 PF07716.15 OQR97400.1 - 3.2 7.9 12.3 0.068 13.3 2.7 2.5 2 0 0 2 2 2 0 Basic region leucine zipper Noelin-1 PF12308.8 OQR97401.1 - 0.055 13.5 7.6 2.1 8.4 0.0 4.6 4 0 0 4 4 4 0 Neurogenesis glycoprotein UvrD-helicase PF00580.21 OQR97401.1 - 1.3 8.5 11.5 3.2 7.2 0.7 3.4 3 0 0 3 3 3 0 UvrD/REP helicase N-terminal domain partial_CstF PF15861.5 OQR97401.1 - 5.4 6.9 6.1 36 4.2 0.1 3.1 3 0 0 3 3 3 0 Partial cleavage stimulation factor domain DASH_Hsk3 PF08227.11 OQR97401.1 - 7.4 7.0 18.8 23 5.5 0.2 4.9 4 0 0 4 4 4 0 DASH complex subunit Hsk3 like Pkinase PF00069.25 OQR97402.1 - 3.9e-52 177.2 0.0 5.4e-52 176.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQR97402.1 - 1.9e-48 165.0 0.0 2.5e-48 164.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase LRR_8 PF13855.6 OQR97402.1 - 6.1e-09 35.5 18.7 3.2e-05 23.6 3.9 2.9 3 0 0 3 3 3 2 Leucine rich repeat LRR_4 PF12799.7 OQR97402.1 - 1.2e-08 35.1 19.9 0.0016 18.8 5.2 3.8 3 0 0 3 3 3 3 Leucine Rich repeats (2 copies) SKG6 PF08693.10 OQR97402.1 - 0.0034 16.8 1.5 0.0086 15.5 1.5 1.7 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Pkinase_fungal PF17667.1 OQR97402.1 - 0.0057 15.5 0.0 0.0091 14.8 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 OQR97402.1 - 0.013 15.4 0.0 0.02 14.8 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 OQR97402.1 - 0.023 13.7 0.0 0.04 12.9 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain Rax2 PF12768.7 OQR97402.1 - 0.028 13.9 0.1 0.072 12.5 0.0 1.8 2 0 0 2 2 2 0 Cortical protein marker for cell polarity CD34_antigen PF06365.12 OQR97402.1 - 0.068 12.7 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 CD34/Podocalyxin family LapA_dom PF06305.11 OQR97402.1 - 0.1 12.5 0.2 0.1 12.5 0.2 1.8 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain LRR_6 PF13516.6 OQR97402.1 - 4.2 7.7 11.1 15 6.0 0.7 4.7 4 0 0 4 4 4 0 Leucine Rich repeat RGS PF00615.19 OQR97407.1 - 1.9e-72 241.0 26.0 1.5e-22 80.1 4.1 5.3 5 0 0 5 5 5 5 Regulator of G protein signaling domain RGS-like PF09128.11 OQR97407.1 - 6.8e-06 25.9 10.5 0.004 16.9 0.3 4.3 4 0 0 4 4 4 2 Regulator of G protein signalling-like domain FAIM1 PF06905.13 OQR97408.1 - 0.039 13.7 0.0 0.071 12.8 0.0 1.3 1 0 0 1 1 1 0 Fas apoptotic inhibitory molecule (FAIM1) Rdx PF10262.9 OQR97409.1 - 6.2e-07 29.5 0.0 1.2e-06 28.6 0.0 1.6 1 1 0 1 1 1 1 Rdx family DUF3788 PF12663.7 OQR97409.1 - 0.017 15.1 0.6 0.092 12.7 0.1 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF3788) PaO PF08417.12 OQR97409.1 - 0.069 13.3 0.0 0.11 12.7 0.0 1.3 1 0 0 1 1 1 0 Pheophorbide a oxygenase DUF365 PF04033.12 OQR97409.1 - 0.096 13.0 0.3 1.8 8.9 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF365) Ovate PF04844.13 OQR97410.1 - 0.1 12.6 0.0 0.23 11.5 0.0 1.6 1 0 0 1 1 1 0 Transcriptional repressor, ovate QueH PF02677.14 OQR97412.1 - 1.3e-56 191.5 1.9 1.9e-56 190.9 1.9 1.2 1 0 0 1 1 1 1 Epoxyqueuosine reductase QueH Myosin_head PF00063.21 OQR97414.1 - 1.9e-218 727.0 0.2 3.2e-218 726.3 0.0 1.4 2 0 0 2 2 2 1 Myosin head (motor domain) IQ PF00612.27 OQR97414.1 - 1.1e-13 49.7 35.9 0.00023 20.7 1.7 6.0 5 0 0 5 5 5 5 IQ calmodulin-binding motif POTRA_2 PF08479.11 OQR97414.1 - 0.01 15.7 0.0 0.024 14.4 0.0 1.6 1 0 0 1 1 1 1 POTRA domain, ShlB-type Myosin_N PF02736.19 OQR97414.1 - 0.028 14.3 0.3 0.057 13.3 0.3 1.5 1 0 0 1 1 1 0 Myosin N-terminal SH3-like domain FlgI PF02119.16 OQR97414.1 - 0.072 12.0 1.9 0.063 12.2 0.3 1.6 2 0 0 2 2 2 0 Flagellar P-ring protein CCDC-167 PF15188.6 OQR97414.1 - 0.42 11.0 3.9 0.38 11.1 0.7 2.7 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 Leu_zip PF15294.6 OQR97414.1 - 0.64 9.5 11.4 2.2 7.7 6.1 2.6 2 0 0 2 2 2 0 Leucine zipper DUF87 PF01935.17 OQR97414.1 - 4.4 7.3 5.2 12 5.9 0.1 3.3 3 0 0 3 3 3 0 Helicase HerA, central domain YabA PF06156.13 OQR97414.1 - 8.9 7.0 13.2 1.8 9.2 5.1 3.4 3 0 0 3 3 3 0 Initiation control protein YabA Thioredoxin_8 PF13905.6 OQR97415.1 - 1.9e-24 85.8 0.1 2.4e-24 85.5 0.1 1.1 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin PF00085.20 OQR97415.1 - 5.4e-10 39.2 0.1 1.8e-06 27.9 0.0 2.1 1 1 1 2 2 2 2 Thioredoxin Redoxin PF08534.10 OQR97415.1 - 4e-09 36.3 0.0 5e-09 36.0 0.0 1.1 1 0 0 1 1 1 1 Redoxin Thioredoxin_2 PF13098.6 OQR97415.1 - 1.1e-07 32.3 0.0 1.6e-07 31.8 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like domain AhpC-TSA PF00578.21 OQR97415.1 - 3.8e-06 26.8 0.0 5.5e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_9 PF14595.6 OQR97415.1 - 0.00053 19.8 0.0 0.1 12.4 0.0 2.1 1 1 0 1 1 1 1 Thioredoxin TraF PF13728.6 OQR97415.1 - 0.0036 17.2 0.0 0.014 15.3 0.0 1.7 1 1 0 1 1 1 1 F plasmid transfer operon protein Thioredoxin_7 PF13899.6 OQR97415.1 - 0.0098 16.1 0.1 0.044 14.0 0.1 2.1 1 1 0 1 1 1 1 Thioredoxin-like Sugar_tr PF00083.24 OQR97420.1 - 1.1e-106 357.5 25.7 1.2e-106 357.3 25.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OQR97420.1 - 3e-30 105.4 30.1 6.9e-21 74.5 9.3 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 OQR97420.1 - 0.0063 15.1 3.3 0.0063 15.1 3.3 3.3 2 2 1 3 3 3 2 MFS/sugar transport protein Ank_2 PF12796.7 OQR97421.1 - 2.1e-23 82.7 8.6 3.2e-06 27.6 0.1 6.5 2 2 4 7 7 7 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQR97421.1 - 4.9e-15 55.7 18.3 0.00089 19.8 0.2 8.6 8 3 1 10 10 10 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 OQR97421.1 - 1.1e-13 51.1 2.8 1 9.7 0.0 8.4 5 3 4 9 9 9 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQR97421.1 - 1.4e-12 46.6 3.6 5.7 7.9 0.0 10.2 12 0 0 12 12 12 4 Ankyrin repeat Ank PF00023.30 OQR97421.1 - 0.024 15.1 4.6 96 3.7 0.0 6.7 8 1 0 8 8 8 0 Ankyrin repeat Pkinase_Tyr PF07714.17 OQR97421.1 - 0.082 12.2 0.1 1.6 8.0 0.0 2.4 2 0 0 2 2 2 0 Protein tyrosine kinase FAO_M PF16350.5 OQR97421.1 - 0.1 13.0 0.0 16 5.9 0.0 3.6 3 0 0 3 3 3 0 FAD dependent oxidoreductase central domain BT1 PF03092.16 OQR97422.1 - 8.1e-10 37.5 7.4 8e-09 34.3 0.6 2.7 3 0 0 3 3 3 2 BT1 family HA PF03457.14 OQR97423.1 - 2.6e-17 62.9 0.1 0.0073 16.6 0.0 8.8 7 2 0 7 7 7 5 Helicase associated domain DUF1216 PF06746.11 OQR97423.1 - 0.31 11.1 0.0 0.31 11.1 0.0 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1216) Ank_4 PF13637.6 OQR97427.1 - 1.3e-16 60.7 1.9 0.00025 21.5 0.0 5.6 4 1 1 5 5 5 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 OQR97427.1 - 2.1e-12 47.5 0.6 7.6e-06 26.4 0.2 3.6 1 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OQR97427.1 - 7.3e-10 38.2 2.8 7.2 7.5 0.0 7.5 6 1 1 7 7 7 3 Ankyrin repeat Ank_5 PF13857.6 OQR97427.1 - 9.4e-08 32.2 4.6 0.45 10.9 0.0 6.3 3 2 3 6 6 6 2 Ankyrin repeats (many copies) Ank PF00023.30 OQR97427.1 - 0.2 12.1 1.5 54 4.5 0.1 4.8 2 2 2 4 4 4 0 Ankyrin repeat EF-hand_7 PF13499.6 OQR97429.1 - 1.5e-05 25.3 2.3 0.00015 22.1 0.2 2.4 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_8 PF13833.6 OQR97429.1 - 4.7e-05 23.2 1.7 0.028 14.3 0.1 2.6 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 OQR97429.1 - 0.0002 20.7 2.8 0.15 11.7 0.4 2.3 2 0 0 2 2 2 2 EF hand EF-hand_5 PF13202.6 OQR97429.1 - 0.0011 18.4 0.3 0.0055 16.1 0.1 2.0 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.6 OQR97429.1 - 0.0044 16.8 0.2 0.07 13.1 0.0 2.3 2 0 0 2 2 2 1 EF-hand domain PhnJ PF06007.11 OQR97429.1 - 0.025 13.6 0.0 0.055 12.5 0.0 1.5 1 0 0 1 1 1 0 Phosphonate metabolism protein PhnJ Peptidase_M48 PF01435.18 OQR97430.1 - 7e-11 42.3 0.5 1.1e-10 41.6 0.5 1.5 1 1 0 1 1 1 1 Peptidase family M48 DUF2201_N PF13203.6 OQR97430.1 - 0.088 12.4 0.0 0.12 11.9 0.0 1.2 1 0 0 1 1 1 0 Putative metallopeptidase domain DEK_C PF08766.11 OQR97431.1 - 1.4e-07 31.4 4.1 2.3e-07 30.6 4.1 1.3 1 0 0 1 1 1 1 DEK C terminal domain DUF4342 PF14242.6 OQR97431.1 - 0.024 14.6 0.1 0.036 14.1 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4342) PP2C_C PF07830.13 OQR97431.1 - 0.036 14.5 1.4 0.048 14.1 0.6 1.6 1 1 0 1 1 1 0 Protein serine/threonine phosphatase 2C, C-terminal domain Cytochrom_B562 PF07361.11 OQR97431.1 - 0.041 14.5 1.3 0.096 13.4 0.6 1.9 1 1 1 2 2 2 0 Cytochrome b562 DUF962 PF06127.11 OQR97432.1 - 0.59 10.2 6.2 0.078 13.1 2.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF962) Glyco_transf_20 PF00982.21 OQR97433.1 - 1.9e-110 369.8 0.0 2.7e-110 369.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.16 OQR97433.1 - 2.5e-36 125.0 0.0 6.9e-36 123.5 0.0 1.8 1 1 0 1 1 1 1 Trehalose-phosphatase CBM_20 PF00686.19 OQR97433.1 - 1.9e-08 34.1 0.0 4.8e-08 32.8 0.0 1.7 1 0 0 1 1 1 1 Starch binding domain DUF4382 PF14321.6 OQR97433.1 - 0.023 14.9 0.1 0.1 12.8 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4382) Hydrolase_3 PF08282.12 OQR97433.1 - 0.054 13.2 0.0 0.28 10.9 0.0 2.1 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase Cu-oxidase_2 PF07731.14 OQR97434.1 - 2.2e-20 72.8 1.5 2.2e-20 72.8 1.5 2.3 2 1 0 2 2 2 1 Multicopper oxidase Cu-oxidase_3 PF07732.15 OQR97434.1 - 1.4e-05 25.1 0.3 0.00023 21.2 0.4 2.5 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase PF00394.22 OQR97434.1 - 0.00073 19.7 0.0 0.0019 18.3 0.0 1.8 2 0 0 2 2 2 1 Multicopper oxidase Glug PF07581.12 OQR97434.1 - 0.15 12.6 0.7 0.38 11.3 0.7 1.7 1 0 0 1 1 1 0 The GLUG motif Ribonuc_2-5A PF06479.12 OQR97435.1 - 0.0066 16.6 0.3 0.0091 16.2 0.3 1.3 1 0 0 1 1 1 1 Ribonuclease 2-5A BLOC1S3 PF15753.5 OQR97435.1 - 0.12 12.5 3.9 0.15 12.2 3.9 1.2 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex 1 subunit 3 Glycophorin_A PF01102.18 OQR97442.1 - 0.073 13.3 0.0 0.15 12.3 0.0 1.5 1 0 0 1 1 1 0 Glycophorin A cNMP_binding PF00027.29 OQR97443.1 - 2.5e-21 75.6 0.1 2.3e-10 40.4 0.1 4.4 4 1 0 4 4 4 3 Cyclic nucleotide-binding domain DUF4734 PF15881.5 OQR97443.1 - 0.0018 18.4 0.0 0.0093 16.1 0.0 2.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4734) Pkinase_Tyr PF07714.17 OQR97444.1 - 5.5e-86 288.0 0.0 1.3e-49 168.9 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 OQR97444.1 - 4.1e-84 282.1 0.0 5.2e-48 163.7 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_fungal PF17667.1 OQR97444.1 - 6.8e-06 25.1 0.3 3.4e-05 22.8 0.0 1.9 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 OQR97444.1 - 1.7e-05 24.3 0.0 0.013 14.8 0.0 3.3 3 1 0 3 3 3 2 Kinase-like APH PF01636.23 OQR97444.1 - 0.0011 19.0 0.1 0.053 13.4 0.0 2.2 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 OQR97444.1 - 0.0012 18.3 0.1 0.071 12.5 0.0 2.2 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 OQR97444.1 - 0.0092 15.0 0.5 0.07 12.1 0.1 2.4 2 1 0 2 2 2 1 Haspin like kinase domain LRR_8 PF13855.6 OQR97445.1 - 3.2e-36 122.9 60.1 1.8e-11 43.6 5.9 7.2 5 1 1 6 6 6 6 Leucine rich repeat LRR_4 PF12799.7 OQR97445.1 - 3.9e-34 116.1 60.0 1.5e-05 25.2 0.0 9.6 6 3 3 9 9 9 9 Leucine Rich repeats (2 copies) WW PF00397.26 OQR97445.1 - 3.4e-23 81.4 21.8 3.5e-10 39.8 3.6 4.4 4 0 0 4 4 4 3 WW domain LRR_1 PF00560.33 OQR97445.1 - 4.4e-07 29.6 50.1 10 7.1 0.9 14.4 14 1 0 14 14 14 2 Leucine Rich Repeat LRR_9 PF14580.6 OQR97445.1 - 2.2e-05 24.0 22.4 0.0013 18.2 2.5 4.1 2 1 2 4 4 4 4 Leucine-rich repeat TPR_1 PF00515.28 OQR97445.1 - 0.00011 21.9 4.0 0.85 9.6 0.0 4.5 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_2 PF07719.17 OQR97445.1 - 0.00013 21.8 7.4 0.16 12.1 0.0 4.9 6 0 0 6 6 6 2 Tetratricopeptide repeat IQ PF00612.27 OQR97445.1 - 0.0014 18.2 9.6 0.29 11.0 0.3 2.9 2 0 0 2 2 2 2 IQ calmodulin-binding motif TPR_6 PF13174.6 OQR97445.1 - 0.0033 18.0 2.0 2 9.2 0.1 4.7 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_11 PF13414.6 OQR97445.1 - 0.039 13.6 3.1 6.2 6.6 0.0 3.8 3 1 1 4 4 4 0 TPR repeat RsmF_methylt_CI PF17126.5 OQR97445.1 - 0.18 11.9 0.4 24 5.0 0.0 4.0 4 0 0 4 4 3 0 RsmF rRNA methyltransferase first C-terminal domain TPR_19 PF14559.6 OQR97445.1 - 0.19 12.2 3.7 27 5.4 0.1 3.9 3 1 0 4 4 3 0 Tetratricopeptide repeat LRR_5 PF13306.6 OQR97445.1 - 0.29 11.1 0.7 0.93 9.5 0.2 2.1 2 0 0 2 2 2 0 BspA type Leucine rich repeat region (6 copies) Hydrolase_2 PF07486.12 OQR97445.1 - 4.6 8.2 6.6 6.5 7.7 0.3 3.9 1 1 2 3 3 3 0 Cell Wall Hydrolase PsbN PF02468.15 OQR97446.1 - 0.53 10.2 4.2 1 9.2 4.2 1.5 1 0 0 1 1 1 0 Photosystem II reaction centre N protein (psbN) FYVE_2 PF02318.16 OQR97448.1 - 0.84 9.9 10.2 0.035 14.3 4.3 1.8 2 0 0 2 2 2 0 FYVE-type zinc finger UPF1_Zn_bind PF09416.10 OQR97449.1 - 2.7e-75 251.4 4.2 9.4e-74 246.5 3.0 2.6 3 0 0 3 3 2 1 RNA helicase (UPF2 interacting domain) AAA_12 PF13087.6 OQR97449.1 - 4e-60 202.9 0.0 6.4e-60 202.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 OQR97449.1 - 8e-51 173.3 3.7 1.9e-30 106.5 0.2 2.3 1 1 1 2 2 2 2 AAA domain DUF5599 PF18141.1 OQR97449.1 - 4.3e-26 91.0 0.0 1.2e-25 89.6 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF5599) AAA_30 PF13604.6 OQR97449.1 - 2.2e-14 53.7 1.8 1.4e-13 51.0 1.8 2.1 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 OQR97449.1 - 2.8e-12 47.2 0.6 6.7e-12 46.0 0.6 1.7 1 1 0 1 1 1 1 AAA domain UvrD-helicase PF00580.21 OQR97449.1 - 4.2e-06 26.5 0.5 0.0012 18.4 0.4 2.3 1 1 1 2 2 2 2 UvrD/REP helicase N-terminal domain Helicase_RecD PF05127.14 OQR97449.1 - 2.6e-05 24.2 0.4 9.4e-05 22.3 0.4 2.0 1 1 0 1 1 1 1 Helicase ResIII PF04851.15 OQR97449.1 - 5.1e-05 23.3 0.0 9.8e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF2075 PF09848.9 OQR97449.1 - 8.4e-05 22.0 4.3 0.0006 19.2 0.8 3.2 3 1 0 3 3 3 1 Uncharacterized conserved protein (DUF2075) ATPase PF06745.13 OQR97449.1 - 0.00089 18.7 0.0 0.0015 17.9 0.0 1.2 1 0 0 1 1 1 1 KaiC Viral_helicase1 PF01443.18 OQR97449.1 - 0.0015 18.3 0.0 0.87 9.3 0.0 2.8 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase PIF1 PF05970.14 OQR97449.1 - 0.0042 16.3 0.1 0.94 8.6 0.0 2.2 2 0 0 2 2 2 2 PIF1-like helicase PhoH PF02562.16 OQR97449.1 - 0.011 15.2 0.1 0.036 13.5 0.0 1.8 2 0 0 2 2 2 0 PhoH-like protein AAA_22 PF13401.6 OQR97449.1 - 0.016 15.5 0.1 0.036 14.3 0.1 1.6 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 OQR97449.1 - 0.048 14.0 0.5 0.12 12.8 0.5 1.7 1 1 0 1 1 1 0 AAA ATPase domain AAA_5 PF07728.14 OQR97449.1 - 0.071 13.1 0.0 0.47 10.4 0.0 2.4 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) DEAD PF00270.29 OQR97449.1 - 0.071 12.9 0.1 0.13 12.0 0.1 1.4 1 0 0 1 1 1 0 DEAD/DEAH box helicase AAA PF00004.29 OQR97449.1 - 0.1 13.0 0.0 0.22 12.0 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 OQR97449.1 - 0.15 11.6 0.0 0.3 10.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain DAHP_synth_1 PF00793.20 OQR97450.1 - 2.3e-55 187.4 0.0 3.2e-55 186.9 0.0 1.1 1 0 0 1 1 1 1 DAHP synthetase I family Pept_tRNA_hydro PF01195.19 OQR97451.1 - 1.2e-44 152.3 0.0 2.9e-44 151.0 0.0 1.6 1 1 0 1 1 1 1 Peptidyl-tRNA hydrolase Rep_fac-A_C PF08646.10 OQR97456.1 - 8e-41 139.2 3.5 8e-41 139.2 3.5 2.1 3 0 0 3 3 3 1 Replication factor-A C terminal domain REPA_OB_2 PF16900.5 OQR97456.1 - 2e-31 107.8 0.1 9e-29 99.3 0.0 2.4 2 0 0 2 2 2 2 Replication protein A OB domain Rep-A_N PF04057.12 OQR97456.1 - 5.5e-22 77.7 0.0 1.8e-21 76.0 0.0 1.9 2 0 0 2 2 2 1 Replication factor-A protein 1, N-terminal domain tRNA_anti-codon PF01336.25 OQR97456.1 - 2.4e-13 49.8 0.3 9.8e-10 38.3 0.0 3.8 4 0 0 4 4 4 2 OB-fold nucleic acid binding domain DUF4503 PF14951.6 OQR97456.1 - 0.071 11.6 0.1 0.11 10.9 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4503) C1_1 PF00130.22 OQR97456.1 - 0.77 9.7 2.9 1.6 8.7 2.9 1.4 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Kinesin PF00225.23 OQR97457.1 - 4e-99 331.7 1.3 8.2e-99 330.7 1.3 1.5 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 OQR97457.1 - 3.6e-23 82.1 0.1 1.3e-22 80.4 0.1 1.9 1 0 0 1 1 1 1 Microtubule binding DUF2381 PF09544.10 OQR97457.1 - 0.42 10.1 3.5 0.32 10.5 1.5 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2381) PPR_2 PF13041.6 OQR97458.1 - 1.7e-17 63.4 12.8 2.2e-11 43.8 0.2 5.9 5 1 1 6 6 6 4 PPR repeat family DUF3522 PF12036.8 OQR97458.1 - 2.4e-17 63.8 9.9 1e-16 61.8 9.9 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF3522) PPR_long PF17177.4 OQR97458.1 - 1.2e-08 34.6 0.2 0.0094 15.3 0.5 3.7 2 1 0 3 3 3 3 Pentacotripeptide-repeat region of PRORP PPR PF01535.20 OQR97458.1 - 1.6e-08 34.3 3.1 4.9e-05 23.3 0.1 4.8 4 0 0 4 4 4 1 PPR repeat PPR_3 PF13812.6 OQR97458.1 - 4.9e-07 29.7 2.8 0.02 15.0 0.1 5.1 5 1 0 5 5 5 1 Pentatricopeptide repeat domain PPR_1 PF12854.7 OQR97458.1 - 0.038 13.7 7.2 0.53 10.0 0.0 4.6 5 0 0 5 5 5 0 PPR repeat WW PF00397.26 OQR97459.1 - 8.1e-24 83.4 25.4 6.4e-07 29.3 0.3 4.4 4 0 0 4 4 4 4 WW domain ADH_zinc_N PF00107.26 OQR97459.1 - 7.2e-21 74.5 0.1 2.6e-20 72.7 0.1 1.9 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 OQR97459.1 - 2.3e-18 66.1 0.8 2.3e-18 66.1 0.8 2.4 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain Glu_dehyd_C PF16912.5 OQR97459.1 - 0.0013 18.2 0.0 0.0025 17.4 0.0 1.3 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus IQ PF00612.27 OQR97459.1 - 0.0018 17.9 0.3 0.0018 17.9 0.3 5.2 5 0 0 5 5 5 2 IQ calmodulin-binding motif Hydrolase_2 PF07486.12 OQR97459.1 - 0.0064 17.3 7.8 7.1 7.5 0.1 3.9 2 1 2 4 4 4 2 Cell Wall Hydrolase AlaDh_PNT_C PF01262.21 OQR97459.1 - 0.0071 15.7 0.2 0.014 14.7 0.2 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 OQR97459.1 - 0.061 12.7 0.0 0.14 11.5 0.0 1.6 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain TrkA_N PF02254.18 OQR97459.1 - 0.18 12.1 0.0 0.39 11.0 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain LRR_6 PF13516.6 OQR97461.1 - 4.1e-13 48.2 13.6 0.0006 19.7 0.1 5.5 5 0 0 5 5 5 4 Leucine Rich repeat DUF4476 PF14771.6 OQR97461.1 - 4.1e-05 23.8 0.2 0.00018 21.7 0.2 2.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4476) ABC_membrane PF00664.23 OQR97462.1 - 3.4e-42 145.0 1.0 4.8e-42 144.5 1.0 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 OQR97462.1 - 2.7e-31 108.9 0.0 4.4e-31 108.2 0.0 1.3 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 OQR97462.1 - 4e-06 26.4 1.2 7.6e-05 22.2 0.1 2.1 1 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 OQR97462.1 - 0.00012 21.7 0.1 0.00028 20.6 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_30 PF13604.6 OQR97462.1 - 0.00098 18.9 0.1 0.0039 16.9 0.1 1.9 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 OQR97462.1 - 0.00099 19.4 1.7 0.064 13.5 1.1 3.1 2 1 0 2 2 2 1 AAA domain AAA_25 PF13481.6 OQR97462.1 - 0.0013 18.4 0.7 0.3 10.6 0.0 3.1 3 0 0 3 3 3 1 AAA domain Zeta_toxin PF06414.12 OQR97462.1 - 0.0041 16.4 0.1 0.011 15.0 0.1 1.6 1 0 0 1 1 1 1 Zeta toxin AAA_16 PF13191.6 OQR97462.1 - 0.0057 17.1 0.1 0.02 15.3 0.1 2.0 1 1 0 1 1 1 1 AAA ATPase domain ABC_ATPase PF09818.9 OQR97462.1 - 0.0092 14.8 0.1 0.031 13.1 0.1 1.8 2 0 0 2 2 2 1 Predicted ATPase of the ABC class AAA_21 PF13304.6 OQR97462.1 - 0.027 14.3 2.4 0.57 9.9 0.0 2.2 1 1 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system APS_kinase PF01583.20 OQR97462.1 - 0.056 13.3 0.5 0.24 11.3 0.2 2.2 2 0 0 2 2 2 0 Adenylylsulphate kinase AAA_18 PF13238.6 OQR97462.1 - 0.075 13.6 0.0 0.26 11.9 0.0 2.0 2 0 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 OQR97462.1 - 0.088 12.7 0.4 0.32 10.9 0.1 2.0 2 0 0 2 2 2 0 RsgA GTPase AAA_33 PF13671.6 OQR97462.1 - 0.11 12.7 0.1 0.33 11.1 0.0 2.0 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 OQR97462.1 - 0.17 12.0 0.2 1.9 8.6 0.1 2.3 2 0 0 2 2 2 0 50S ribosome-binding GTPase DEAD PF00270.29 OQR97462.1 - 0.23 11.2 1.1 1.1 9.0 0.5 2.2 2 1 0 2 2 2 0 DEAD/DEAH box helicase EF-hand_1 PF00036.32 OQR97468.1 - 7.7e-15 53.3 8.7 3.6e-06 26.1 0.5 4.2 4 0 0 4 4 4 3 EF hand EF-hand_7 PF13499.6 OQR97468.1 - 1.2e-13 51.3 7.3 8.4e-07 29.4 0.8 2.7 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 OQR97468.1 - 1.8e-13 49.2 10.7 0.00011 21.9 0.2 4.4 4 0 0 4 4 4 3 EF-hand domain EF-hand_5 PF13202.6 OQR97468.1 - 2.3e-10 39.5 4.9 3.3e-06 26.3 0.3 4.0 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.6 OQR97468.1 - 2.9e-10 39.8 7.2 8.7e-06 25.5 0.3 3.2 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_4 PF12763.7 OQR97468.1 - 0.052 13.5 2.6 2.1 8.3 0.1 3.5 2 2 1 3 3 3 0 Cytoskeletal-regulatory complex EF hand Peptidase_M22 PF00814.25 OQR97469.1 - 2.2e-84 283.4 0.0 2.6e-84 283.1 0.0 1.0 1 0 0 1 1 1 1 Glycoprotease family Carbam_trans_N PF02543.15 OQR97469.1 - 0.0013 18.5 0.0 0.0035 17.1 0.0 1.7 2 0 0 2 2 2 1 Carbamoyltransferase N-terminus Glyco_hydro_18 PF00704.28 OQR97474.1 - 1.6e-18 67.5 2.1 1.6e-18 67.5 2.1 2.0 1 1 0 2 2 2 1 Glycosyl hydrolases family 18 DUF4134 PF13572.6 OQR97474.1 - 0.027 14.7 1.7 8.5 6.7 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4134) DUF2613 PF11021.8 OQR97474.1 - 0.11 12.7 1.1 0.22 11.6 1.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2613) Vault PF01505.18 OQR97475.1 - 2.6e-53 177.9 0.2 6.2e-14 51.9 0.0 5.0 4 0 0 4 4 4 4 Major Vault Protein repeat domain MVP_shoulder PF11978.8 OQR97475.1 - 1.5e-50 170.2 0.0 3.9e-50 168.8 0.0 1.8 2 0 0 2 2 2 1 Shoulder domain Vault_2 PF17794.1 OQR97475.1 - 1.7e-32 111.6 0.1 3.9e-18 65.6 0.1 3.3 3 0 0 3 3 3 2 Major Vault Protein repeat domain Vault_3 PF17795.1 OQR97475.1 - 2.9e-32 110.5 0.3 6.3e-27 93.4 0.1 3.6 3 0 0 3 3 3 3 Major Vault Protein Repeat domain Vault_4 PF17796.1 OQR97475.1 - 4.2e-27 94.0 0.0 4.9e-26 90.6 0.1 2.8 2 0 0 2 2 2 1 Major Vault Protein repeat domain DUF3601 PF12208.8 OQR97475.1 - 0.00014 21.9 0.5 0.27 11.4 0.0 4.0 3 2 2 5 5 5 1 Domain of unknown function (DUF3601) HA PF03457.14 OQR97476.1 - 6.8e-32 109.6 5.1 3.6e-11 43.2 0.6 4.0 4 0 0 4 4 4 3 Helicase associated domain Med26 PF08711.11 OQR97476.1 - 0.02 14.9 0.2 8.5 6.5 0.0 3.1 3 0 0 3 3 3 0 TFIIS helical bundle-like domain Gpi1 PF05024.15 OQR97476.1 - 0.42 10.7 1.3 14 5.8 0.1 2.6 3 0 0 3 3 3 0 N-acetylglucosaminyl transferase component (Gpi1) CTD_bind PF04818.13 OQR97477.1 - 6.6e-07 30.1 0.0 1.7e-06 28.7 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase II-binding domain. CFIA_Pcf11 PF11526.8 OQR97477.1 - 0.037 14.5 2.6 0.091 13.3 2.6 1.6 1 0 0 1 1 1 0 Subunit of cleavage factor IA Pcf11 DUF4326 PF14216.6 OQR97478.1 - 1.1e-22 80.5 0.0 2.1e-22 79.6 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4326) PHD PF00628.29 OQR97479.1 - 8.5e-18 64.0 27.7 4.3e-09 36.1 9.4 3.6 3 0 0 3 3 3 2 PHD-finger Ank_4 PF13637.6 OQR97479.1 - 6e-16 58.6 1.8 0.012 16.2 0.0 4.9 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQR97479.1 - 2.1e-15 55.3 6.8 0.0025 18.2 0.0 6.8 6 0 0 6 6 6 2 Ankyrin repeat Ank PF00023.30 OQR97479.1 - 2.9e-15 55.9 11.2 0.028 14.9 0.0 7.1 7 0 0 7 7 7 4 Ankyrin repeat Ank_2 PF12796.7 OQR97479.1 - 6.1e-15 55.6 2.5 3.2e-06 27.6 0.0 3.9 2 1 3 5 5 4 4 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OQR97479.1 - 8.2e-13 48.3 3.2 0.0035 17.6 0.0 4.8 4 1 1 5 5 5 5 Ankyrin repeats (many copies) PHD_2 PF13831.6 OQR97479.1 - 1.2e-06 28.0 15.4 0.00062 19.3 2.6 3.4 3 0 0 3 3 3 2 PHD-finger PBP1_TM PF14812.6 OQR97479.1 - 0.013 15.9 9.6 0.013 15.9 9.6 2.3 3 0 0 3 3 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal JmjC PF02373.22 OQR97479.1 - 0.023 15.1 0.0 0.071 13.6 0.0 1.9 1 0 0 1 1 1 0 JmjC domain, hydroxylase DUF1877 PF08974.10 OQR97479.1 - 0.098 12.7 0.3 0.63 10.1 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1877) Prok-RING_1 PF14446.6 OQR97479.1 - 0.66 10.0 18.2 0.96 9.4 2.0 3.2 3 0 0 3 3 2 0 Prokaryotic RING finger family 1 RXT2_N PF08595.11 OQR97479.1 - 5.4 7.0 8.8 10 6.1 3.1 2.4 2 0 0 2 2 2 0 RXT2-like, N-terminal Cwf_Cwc_15 PF04889.12 OQR97479.1 - 8.8 6.0 19.9 7.3 6.2 10.0 2.3 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Choline_transpo PF04515.12 OQR97480.1 - 2.9e-38 131.9 12.5 2.9e-38 131.9 12.5 2.4 2 1 0 2 2 2 2 Plasma-membrane choline transporter TFIIS_M PF07500.14 OQR97481.1 - 8.6e-17 61.6 0.0 3.5e-16 59.7 0.0 2.1 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS), central domain Arm PF00514.23 OQR97481.1 - 0.00071 19.5 17.3 0.18 11.9 0.1 5.9 6 0 0 6 6 6 2 Armadillo/beta-catenin-like repeat EF-hand_4 PF12763.7 OQR97481.1 - 0.0056 16.6 0.0 0.015 15.3 0.0 1.7 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand DUF848 PF05852.11 OQR97481.1 - 1.7 8.7 6.5 6.8 6.8 6.5 2.0 1 0 0 1 1 1 0 Gammaherpesvirus protein of unknown function (DUF848) SlyX PF04102.12 OQR97492.1 - 0.00025 21.6 8.2 0.096 13.3 0.3 3.8 3 0 0 3 3 3 2 SlyX HAP1_N PF04849.13 OQR97492.1 - 0.0023 17.2 5.7 0.038 13.2 0.5 3.0 2 1 0 2 2 2 2 HAP1 N-terminal conserved region F_actin_bind PF08919.10 OQR97492.1 - 0.11 12.6 1.8 3.2 7.9 0.3 3.0 2 0 0 2 2 2 0 F-actin binding ABC_tran_CTD PF16326.5 OQR97492.1 - 0.24 11.7 1.6 1.5 9.1 0.1 2.7 2 0 0 2 2 2 0 ABC transporter C-terminal domain TPR_1 PF00515.28 OQR97493.1 - 3.7e-113 365.2 36.9 2.2e-10 39.9 0.2 15.2 15 0 0 15 15 15 13 Tetratricopeptide repeat TPR_2 PF07719.17 OQR97493.1 - 3.8e-92 295.2 35.6 6.8e-09 35.2 0.2 14.5 15 0 0 15 15 15 13 Tetratricopeptide repeat TPR_11 PF13414.6 OQR97493.1 - 4.4e-86 282.3 44.3 9.6e-09 34.8 0.1 14.0 3 2 11 14 14 14 13 TPR repeat TPR_17 PF13431.6 OQR97493.1 - 3.3e-69 224.4 33.6 2.2e-05 24.5 0.0 13.8 14 0 0 14 14 13 12 Tetratricopeptide repeat TPR_8 PF13181.6 OQR97493.1 - 5.7e-69 222.6 22.3 1.7e-05 24.7 0.5 13.8 14 0 0 14 14 13 13 Tetratricopeptide repeat TPR_9 PF13371.6 OQR97493.1 - 3.2e-45 152.1 1.8 3.1e-06 27.2 0.3 10.0 3 3 5 10 10 10 10 Tetratricopeptide repeat TPR_16 PF13432.6 OQR97493.1 - 1.3e-38 131.3 26.0 1.6e-07 31.9 1.0 8.6 4 3 6 10 10 10 9 Tetratricopeptide repeat TPR_12 PF13424.6 OQR97493.1 - 1.1e-37 128.2 29.4 2.3e-07 31.0 0.9 8.5 4 3 3 7 7 7 7 Tetratricopeptide repeat TPR_7 PF13176.6 OQR97493.1 - 1.5e-31 106.1 24.6 0.0029 17.5 0.1 14.3 14 0 0 14 14 14 6 Tetratricopeptide repeat TPR_6 PF13174.6 OQR97493.1 - 1.8e-27 94.1 21.9 0.1 13.3 0.0 13.5 13 0 0 13 13 13 8 Tetratricopeptide repeat TPR_14 PF13428.6 OQR97493.1 - 2e-24 84.2 8.9 0.11 13.4 0.4 11.8 3 3 9 12 12 12 4 Tetratricopeptide repeat TPR_19 PF14559.6 OQR97493.1 - 4.6e-21 75.1 20.3 0.00031 21.2 0.3 9.0 4 3 6 10 10 10 8 Tetratricopeptide repeat SHNi-TPR PF10516.9 OQR97493.1 - 5.5e-17 60.9 10.2 0.025 14.0 0.1 11.2 12 0 0 12 12 12 3 SHNi-TPR TPR_10 PF13374.6 OQR97493.1 - 3.2e-14 52.2 38.9 0.11 12.4 0.5 12.7 13 0 0 13 13 13 4 Tetratricopeptide repeat ANAPC3 PF12895.7 OQR97493.1 - 1.8e-07 31.3 20.6 0.0084 16.3 0.6 6.4 3 2 2 6 6 6 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_4 PF07721.14 OQR97493.1 - 1.3e-05 25.4 1.6 22 6.0 0.1 7.9 9 0 0 9 9 8 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 OQR97493.1 - 1.8e-05 24.7 18.8 0.56 10.3 0.2 8.2 7 2 2 9 9 9 2 Fis1 C-terminal tetratricopeptide repeat TPR_20 PF14561.6 OQR97493.1 - 0.00043 20.6 9.5 0.4 11.1 0.2 6.1 6 2 2 8 8 8 1 Tetratricopeptide repeat BTAD PF03704.17 OQR97493.1 - 0.00085 19.8 3.5 0.1 13.0 0.2 4.5 2 1 4 6 6 6 1 Bacterial transcriptional activator domain MIT PF04212.18 OQR97493.1 - 0.0014 18.7 25.0 2.9 8.0 0.8 9.7 10 0 0 10 10 10 1 MIT (microtubule interacting and transport) domain Flp_C PF05202.12 OQR97493.1 - 0.0017 17.9 4.4 0.08 12.5 0.0 3.2 3 0 0 3 3 3 1 Recombinase Flp protein Ubiq-assoc PF09145.10 OQR97493.1 - 0.083 12.9 9.8 17 5.5 0.0 6.4 8 0 0 8 8 7 0 Ubiquitin-associated SlyX PF04102.12 OQR97496.1 - 0.026 15.1 0.6 0.026 15.1 0.6 2.8 3 0 0 3 3 3 0 SlyX DUF883 PF05957.13 OQR97496.1 - 0.067 13.8 2.4 0.23 12.1 1.8 2.2 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) Trimer_CC PF08954.11 OQR97496.1 - 0.39 10.3 6.8 2.1 8.0 4.3 2.4 2 0 0 2 2 2 0 Trimerisation motif KIX_2 PF16987.5 OQR97513.1 - 8.7e-05 22.4 0.1 0.00011 22.1 0.1 1.2 1 0 0 1 1 1 1 KIX domain Anoctamin PF04547.12 OQR97514.1 - 1.8e-95 320.5 12.5 3.1e-95 319.7 12.5 1.4 1 0 0 1 1 1 1 Calcium-activated chloride channel Chorismate_bind PF00425.18 OQR97514.1 - 1.9e-94 316.0 0.0 3.4e-94 315.2 0.0 1.4 1 0 0 1 1 1 1 chorismate binding enzyme Anth_synt_I_N PF04715.13 OQR97514.1 - 8.9e-24 84.3 0.1 6.9e-23 81.4 0.0 2.4 2 0 0 2 2 2 1 Anthranilate synthase component I, N terminal region HTH_57 PF18679.1 OQR97514.1 - 0.073 13.4 0.4 0.42 11.0 0.0 2.5 2 0 0 2 2 2 0 ThcOx helix turn helix domain Ank_5 PF13857.6 OQR97515.1 - 5.7e-08 32.9 0.2 2e-07 31.2 0.2 2.0 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 OQR97515.1 - 2.4e-06 28.0 0.1 4.8e-05 23.8 0.1 2.7 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 OQR97515.1 - 3.2e-06 27.6 0.1 7.8e-06 26.4 0.1 1.7 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OQR97515.1 - 7.3e-05 22.9 0.3 0.019 15.5 0.0 3.3 3 0 0 3 3 3 1 Ankyrin repeat Ank PF00023.30 OQR97515.1 - 0.0053 17.2 0.0 0.19 12.2 0.0 3.1 3 0 0 3 3 3 1 Ankyrin repeat Chorismate_bind PF00425.18 OQR97515.1 - 0.042 13.4 0.3 2.6 7.5 0.0 2.5 2 0 0 2 2 2 0 chorismate binding enzyme Lge1 PF11488.8 OQR97515.1 - 0.066 13.4 0.5 0.39 10.9 0.5 2.3 1 0 0 1 1 1 0 Transcriptional regulatory protein LGE1 MIT_LIKE_ACTX PF17556.2 OQR97515.1 - 0.083 13.5 0.0 0.28 11.8 0.0 1.8 2 0 0 2 2 2 0 MIT-like atracotoxin family PP2C PF00481.21 OQR97516.1 - 1.9e-28 99.8 0.0 3.1e-28 99.1 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C Cellulose_synt PF03552.14 OQR97516.1 - 3.3e-24 85.4 6.8 6e-14 51.5 0.6 3.6 2 1 1 3 3 3 3 Cellulose synthase Glyco_trans_2_3 PF13632.6 OQR97516.1 - 1.4e-14 54.5 0.1 6.5e-14 52.3 0.1 2.3 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 OQR97516.1 - 1.2e-09 38.4 0.0 5.4e-09 36.3 0.0 2.0 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 OQR97516.1 - 3.1e-09 36.9 0.1 1e-06 28.7 0.1 3.1 3 1 0 3 3 3 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 OQR97516.1 - 0.00013 21.5 0.0 0.087 12.3 0.0 2.4 2 0 0 2 2 2 2 Glycosyl transferase family 21 PP2C_2 PF13672.6 OQR97516.1 - 0.00075 19.2 0.0 0.0035 17.0 0.0 2.0 1 1 0 1 1 1 1 Protein phosphatase 2C DZR PF12773.7 OQR97516.1 - 0.0024 17.9 0.5 0.0079 16.2 0.5 1.8 1 0 0 1 1 1 1 Double zinc ribbon zinc_ribbon_2 PF13240.6 OQR97516.1 - 0.074 12.8 2.1 0.21 11.4 2.1 1.8 1 0 0 1 1 1 0 zinc-ribbon domain stn_TNFRSF12A PF12191.8 OQR97516.1 - 0.077 13.2 0.0 0.19 12.0 0.0 1.6 1 0 0 1 1 1 0 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain zinc_ribbon_15 PF17032.5 OQR97516.1 - 0.15 12.8 2.4 0.16 12.8 0.6 2.0 2 0 0 2 2 1 0 zinc-ribbon family Nudix_N_2 PF14803.6 OQR97516.1 - 0.16 11.9 1.2 8.3 6.4 0.1 2.7 2 0 0 2 2 2 0 Nudix N-terminal SDA1 PF05285.12 OQR97518.1 - 1.2e-48 166.4 47.0 1.4e-47 162.9 36.3 3.1 2 1 0 2 2 2 1 SDA1 NUC130_3NT PF08158.12 OQR97518.1 - 3e-21 75.5 0.4 9.2e-21 73.9 0.4 1.9 1 0 0 1 1 1 1 NUC130/3NT domain Glycos_transf_2 PF00535.26 OQR97519.1 - 0.00016 21.5 0.0 0.014 15.2 0.0 2.3 2 0 0 2 2 2 1 Glycosyl transferase family 2 DZR PF12773.7 OQR97519.1 - 0.00021 21.2 0.6 0.00053 19.9 0.6 1.6 1 0 0 1 1 1 1 Double zinc ribbon zinc_ribbon_2 PF13240.6 OQR97519.1 - 0.0059 16.3 3.0 0.017 14.8 3.0 1.9 1 0 0 1 1 1 1 zinc-ribbon domain zinc_ribbon_15 PF17032.5 OQR97519.1 - 0.024 15.4 0.1 0.057 14.2 0.1 1.7 1 0 0 1 1 1 0 zinc-ribbon family Nudix_N_2 PF14803.6 OQR97519.1 - 0.13 12.2 2.0 7.8 6.5 0.2 2.4 2 0 0 2 2 2 0 Nudix N-terminal zf-RING_2 PF13639.6 OQR97557.1 - 2.2e-06 27.9 14.5 2.2e-06 27.9 14.5 2.6 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 OQR97557.1 - 3.8e-06 26.6 14.7 3.8e-06 26.6 14.7 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 OQR97557.1 - 5.4e-05 23.0 15.6 5.4e-05 23.0 15.6 2.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 OQR97557.1 - 8.6e-05 22.3 13.5 8.6e-05 22.3 13.5 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OQR97557.1 - 0.00074 19.4 14.1 0.00074 19.4 14.1 2.5 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 OQR97557.1 - 0.004 17.1 8.7 0.004 17.1 8.7 2.8 2 2 0 2 2 2 1 RING-type zinc-finger zf-RING_6 PF14835.6 OQR97557.1 - 0.0082 16.0 5.9 0.0082 16.0 5.9 1.6 2 0 0 2 2 1 1 zf-RING of BARD1-type protein Sina PF03145.16 OQR97557.1 - 0.031 14.2 0.4 0.031 14.2 0.4 2.0 2 1 0 2 2 2 0 Seven in absentia protein family zf-C3HC4_4 PF15227.6 OQR97557.1 - 0.05 13.8 12.8 0.05 13.8 12.8 2.7 2 1 0 2 2 2 0 zinc finger of C3HC4-type, RING DUF4370 PF14290.6 OQR97557.1 - 0.14 12.0 0.1 0.2 11.5 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4370) zf-rbx1 PF12678.7 OQR97557.1 - 0.62 10.4 15.9 0.11 12.8 11.1 2.3 2 1 0 2 2 2 0 RING-H2 zinc finger domain zf-C2H2_6 PF13912.6 OQR97557.1 - 2.1 8.4 6.8 52 4.0 0.4 3.7 3 0 0 3 3 3 0 C2H2-type zinc finger zf-H2C2_2 PF13465.6 OQR97557.1 - 3.1 8.4 13.3 4.8 7.8 0.3 4.4 4 0 0 4 4 4 0 Zinc-finger double domain FYVE PF01363.21 OQR97557.1 - 3.2 8.0 16.7 2.1 8.5 11.5 2.6 2 1 1 3 3 3 0 FYVE zinc finger zf-ANAPC11 PF12861.7 OQR97557.1 - 6.5 6.9 13.1 0.37 10.9 6.8 2.1 2 1 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger Pkinase PF00069.25 OQR97558.1 - 1.6e-79 267.0 0.0 2.2e-79 266.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQR97558.1 - 5e-42 144.0 0.0 6.5e-42 143.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OQR97558.1 - 1.9e-09 37.3 0.0 5e-09 35.9 0.0 1.7 2 0 0 2 2 2 1 Kinase-like RIO1 PF01163.22 OQR97558.1 - 0.0033 17.1 0.1 0.0055 16.3 0.1 1.3 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 OQR97558.1 - 0.014 15.3 0.5 0.04 13.8 0.5 1.7 1 0 0 1 1 1 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 OQR97558.1 - 0.015 14.3 0.1 0.02 13.8 0.1 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Glycos_trans_3N PF02885.17 OQR97558.1 - 0.042 13.7 0.0 0.083 12.8 0.0 1.6 1 0 0 1 1 1 0 Glycosyl transferase family, helical bundle domain Kdo PF06293.14 OQR97558.1 - 0.086 12.2 0.2 0.17 11.2 0.2 1.5 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family ALO PF04030.14 OQR97559.1 - 3.2e-27 96.0 0.3 1.2e-26 94.1 0.3 1.9 1 1 0 1 1 1 1 D-arabinono-1,4-lactone oxidase FAD_binding_4 PF01565.23 OQR97559.1 - 1.1e-23 83.6 0.1 1.7e-23 82.9 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain RNA_pol_Rpb5_C PF01191.19 OQR97559.1 - 0.57 10.1 2.0 2.3 8.2 0.2 2.8 3 0 0 3 3 3 0 RNA polymerase Rpb5, C-terminal domain HECT PF00632.25 OQR97560.1 - 7.1e-79 265.5 0.0 8.4e-79 265.2 0.0 1.0 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) DNA_ligase_A_N PF04675.14 OQR97560.1 - 0.078 13.3 0.0 0.13 12.6 0.0 1.3 1 0 0 1 1 1 0 DNA ligase N terminus His_Phos_1 PF00300.22 OQR97561.1 - 3.4e-33 115.0 0.0 6.1e-26 91.3 0.0 2.1 1 1 1 2 2 2 2 Histidine phosphatase superfamily (branch 1) TAF6_C PF07571.13 OQR97561.1 - 0.033 14.5 0.0 0.062 13.6 0.0 1.4 1 0 0 1 1 1 0 TAF6 C-terminal HEAT repeat domain DUF1996 PF09362.10 OQR97564.1 - 3.7e-77 259.5 0.2 8.1e-77 258.4 0.0 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF1996) PAN_1 PF00024.26 OQR97564.1 - 0.00036 20.4 3.2 0.13 12.2 4.8 2.3 2 0 0 2 2 2 2 PAN domain PAN_4 PF14295.6 OQR97564.1 - 0.0051 16.7 3.6 0.013 15.4 3.6 1.7 1 0 0 1 1 1 1 PAN domain AMP-binding PF00501.28 OQR97565.1 - 3e-61 207.3 0.0 3.8e-61 207.0 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 OQR97565.1 - 4.4e-16 59.6 0.1 2.2e-15 57.4 0.1 2.1 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain UTP25 PF06862.12 OQR97566.1 - 1.2e-137 459.5 2.3 1.2e-137 459.5 2.3 1.7 2 0 0 2 2 2 1 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 SDF PF00375.18 OQR97566.1 - 8.1e-54 183.1 23.6 1.2e-28 100.2 6.6 3.1 2 1 0 2 2 2 2 Sodium:dicarboxylate symporter family Peptidase_S10 PF00450.22 OQR97567.1 - 1.7e-124 416.5 0.3 2.1e-124 416.2 0.3 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Abhydrolase_6 PF12697.7 OQR97567.1 - 0.00062 20.4 0.0 0.0053 17.4 0.0 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family EF-hand_7 PF13499.6 OQR97568.1 - 7.5e-23 80.8 11.1 7.9e-11 42.3 0.8 3.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 OQR97568.1 - 1.7e-19 67.9 13.8 2.8e-05 23.4 0.2 4.9 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.6 OQR97568.1 - 2e-16 58.5 13.7 3.1e-05 23.6 0.2 5.3 4 1 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 OQR97568.1 - 7.3e-15 54.6 17.2 2.6e-05 24.0 0.3 4.8 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.6 OQR97568.1 - 6e-13 47.7 13.1 0.00025 20.4 0.1 5.2 5 1 1 6 6 6 3 EF hand EF-hand_4 PF12763.7 OQR97568.1 - 0.00039 20.3 16.8 0.13 12.2 0.4 4.6 2 1 2 5 5 5 3 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 OQR97568.1 - 0.0066 16.7 7.9 0.1 12.9 1.1 3.3 2 1 1 3 3 3 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_9 PF14658.6 OQR97568.1 - 0.85 10.0 7.5 0.64 10.4 0.1 3.7 4 0 0 4 4 4 0 EF-hand domain EF-hand_10 PF14788.6 OQR97568.1 - 7.8 6.5 8.3 4.2 7.3 0.3 3.5 2 2 1 3 3 3 0 EF hand SDF PF00375.18 OQR97570.1 - 1.8e-53 182.0 39.9 5.4e-30 104.7 12.7 2.9 1 1 1 2 2 2 2 Sodium:dicarboxylate symporter family Glyco_hydro_18 PF00704.28 OQR97571.1 - 1.8e-11 44.4 0.0 2.6e-11 43.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 DSPc PF00782.20 OQR97572.1 - 4.4e-32 110.7 0.0 7.3e-32 110.0 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 OQR97572.1 - 0.021 14.4 0.0 0.038 13.6 0.0 1.4 1 0 0 1 1 1 0 Protein-tyrosine phosphatase CDKN3 PF05706.12 OQR97572.1 - 0.04 13.6 0.1 0.073 12.7 0.1 1.4 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) Pec_lyase_C PF00544.19 OQR97573.1 - 4.9e-07 29.5 6.5 5.1e-06 26.2 6.5 2.1 1 1 0 1 1 1 1 Pectate lyase Epimerase PF01370.21 OQR97639.1 - 2.4e-25 89.4 0.0 3.2e-25 89.0 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 OQR97639.1 - 6.9e-13 48.7 0.0 1.3e-12 47.8 0.0 1.4 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 OQR97639.1 - 3.8e-12 45.9 0.1 5.3e-12 45.4 0.1 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain 3Beta_HSD PF01073.19 OQR97639.1 - 2.8e-10 39.7 0.0 1e-09 37.9 0.1 1.8 2 1 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 OQR97639.1 - 1.7e-08 34.6 0.0 3.2e-08 33.7 0.0 1.5 1 0 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.12 OQR97639.1 - 0.00078 18.7 0.0 0.0014 17.8 0.0 1.5 1 0 0 1 1 1 1 Male sterility protein Polysacc_synt_2 PF02719.15 OQR97639.1 - 0.00089 18.5 0.0 0.0014 17.8 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Sacchrp_dh_NADP PF03435.18 OQR97639.1 - 0.01 16.1 0.0 0.019 15.2 0.0 1.6 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain NmrA PF05368.13 OQR97639.1 - 0.085 12.4 0.0 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 NmrA-like family Pkinase PF00069.25 OQR97640.1 - 1.8e-63 214.4 0.0 2.4e-63 214.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQR97640.1 - 1.1e-26 93.7 0.0 1.7e-26 93.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase WW PF00397.26 OQR97640.1 - 2.5e-05 24.2 0.1 2.5e-05 24.2 0.1 2.8 3 0 0 3 3 3 1 WW domain DUF588 PF04535.12 OQR97640.1 - 0.0013 18.6 0.1 0.0024 17.6 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF588) Haspin_kinase PF12330.8 OQR97640.1 - 0.041 12.8 0.1 0.073 12.0 0.1 1.3 1 0 0 1 1 1 0 Haspin like kinase domain APH PF01636.23 OQR97640.1 - 0.21 11.5 0.4 4.5 7.1 0.1 2.3 1 1 1 2 2 2 0 Phosphotransferase enzyme family DUF3976 PF13121.6 OQR97642.1 - 0.97 9.6 4.6 1.9 8.7 4.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3976) Pkinase PF00069.25 OQR97643.1 - 1.4e-60 204.9 0.0 1.8e-60 204.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQR97643.1 - 3.5e-46 157.6 0.1 4.6e-46 157.2 0.1 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OQR97643.1 - 0.00016 20.6 0.0 0.00025 20.0 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 OQR97643.1 - 0.0016 17.4 0.9 0.0038 16.2 0.8 1.5 1 1 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 OQR97643.1 - 0.0071 15.7 0.0 0.012 15.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 OQR97643.1 - 0.022 14.7 0.0 0.035 14.0 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.14 OQR97643.1 - 0.04 13.3 0.1 0.083 12.2 0.1 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family WW PF00397.26 OQR97644.1 - 8.3e-05 22.6 10.5 0.0013 18.8 4.2 2.9 2 0 0 2 2 2 2 WW domain POLO_box PF00659.18 OQR97644.1 - 0.054 13.7 0.1 0.11 12.7 0.1 1.6 2 0 0 2 2 2 0 POLO box duplicated region Glyco_hyd_101C PF17451.2 OQR97644.1 - 1.3 9.3 7.8 0.16 12.3 2.0 2.2 1 1 1 2 2 2 0 Glycosyl hydrolase 101 beta sandwich domain PP2C PF00481.21 OQR97645.1 - 3e-36 125.4 0.0 4.3e-36 124.9 0.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 OQR97645.1 - 0.00035 20.3 0.0 0.002 17.8 0.0 2.0 1 1 0 1 1 1 1 Protein phosphatase 2C zf-C3HC4_3 PF13920.6 OQR97646.1 - 2.6e-10 40.0 12.2 5.5e-10 38.9 12.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 OQR97646.1 - 2e-09 37.2 12.6 4.4e-09 36.0 12.6 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 OQR97646.1 - 5.3e-09 36.3 11.8 1.4e-08 35.0 11.8 1.7 1 0 0 1 1 1 1 Ring finger domain Prok-RING_4 PF14447.6 OQR97646.1 - 5.7e-08 32.5 12.0 1.2e-07 31.5 12.0 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 OQR97646.1 - 2.8e-07 30.3 12.3 6.3e-07 29.2 12.3 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 OQR97646.1 - 1.5e-06 28.4 8.3 3.5e-06 27.2 8.3 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 OQR97646.1 - 1.5e-06 28.0 10.5 3.9e-06 26.7 10.5 1.8 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 OQR97646.1 - 1.3e-05 25.2 5.1 1.3e-05 25.2 5.1 2.0 1 1 1 2 2 2 1 RING-type zinc-finger zf-P11 PF03854.14 OQR97646.1 - 0.0016 18.0 7.3 0.0016 18.0 7.3 1.8 2 0 0 2 2 2 1 P-11 zinc finger zf-C3HC4_4 PF15227.6 OQR97646.1 - 0.0028 17.8 10.7 0.007 16.5 10.7 1.7 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.6 OQR97646.1 - 0.014 15.2 9.0 0.034 13.9 9.0 1.7 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-ANAPC11 PF12861.7 OQR97646.1 - 0.031 14.3 6.4 0.093 12.8 6.4 1.8 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger RecR PF02132.15 OQR97646.1 - 0.34 10.5 6.9 1.2 8.8 2.3 2.6 2 0 0 2 2 2 0 RecR protein Glyco_hydro_3 PF00933.21 OQR97647.1 - 4.7e-43 147.8 0.0 8.2e-43 147.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.22 OQR97647.1 - 1.6e-42 145.8 0.0 2.3e-42 145.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.6 OQR97647.1 - 8.9e-05 22.5 0.0 0.00021 21.3 0.0 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain Ank_2 PF12796.7 OQR97648.1 - 1.9e-29 102.1 4.0 4.2e-16 59.3 0.2 4.3 2 1 2 4 4 4 3 Ankyrin repeats (3 copies) Ank PF00023.30 OQR97648.1 - 3.5e-20 71.5 9.0 2.3e-06 27.8 0.0 6.0 6 0 0 6 6 6 4 Ankyrin repeat Ank_5 PF13857.6 OQR97648.1 - 9.4e-20 70.4 7.9 5.4e-07 29.8 0.2 5.8 2 1 3 5 5 5 5 Ankyrin repeats (many copies) Ank_4 PF13637.6 OQR97648.1 - 2.1e-19 69.6 3.1 4.5e-06 27.1 0.1 4.6 5 0 0 5 5 5 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQR97648.1 - 1.8e-16 58.6 6.3 0.00023 21.4 0.0 6.5 6 0 0 6 6 6 4 Ankyrin repeat SAPS PF04499.15 OQR97648.1 - 0.0011 17.9 0.0 0.0027 16.6 0.0 1.6 1 0 0 1 1 1 1 SIT4 phosphatase-associated protein Ldh_1_C PF02866.18 OQR97649.1 - 7.9e-52 175.6 0.0 2.1e-51 174.2 0.0 1.7 2 0 0 2 2 2 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.23 OQR97649.1 - 6.4e-46 156.0 0.4 9.8e-46 155.4 0.4 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain 3Beta_HSD PF01073.19 OQR97649.1 - 5.6e-08 32.1 0.0 1.3e-06 27.7 0.0 2.1 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family THF_DHG_CYH_C PF02882.19 OQR97649.1 - 0.0008 18.8 0.6 0.0045 16.3 0.3 2.2 1 1 1 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain NAD_binding_10 PF13460.6 OQR97649.1 - 0.0037 17.2 0.4 0.0059 16.5 0.1 1.6 2 0 0 2 2 2 1 NAD(P)H-binding DapB_N PF01113.20 OQR97649.1 - 0.005 17.0 0.3 0.012 15.8 0.3 1.6 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus Semialdhyde_dh PF01118.24 OQR97649.1 - 0.034 14.6 0.4 0.11 12.9 0.1 2.0 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain VPS13_C PF16909.5 OQR97695.1 - 5.6e-49 166.3 0.1 1.2e-45 155.4 0.0 2.6 2 0 0 2 2 2 2 Vacuolar-sorting-associated 13 protein C-terminal SHR-BD PF06650.12 OQR97695.1 - 4.5e-37 127.9 0.0 4.2e-29 101.8 0.0 4.4 4 0 0 4 4 4 3 SHR-binding domain of vacuolar-sorting associated protein 13 PH PF00169.29 OQR97695.1 - 5.5e-14 52.6 0.0 0.00023 21.6 0.0 4.1 3 0 0 3 3 3 3 PH domain ATG_C PF09333.11 OQR97695.1 - 1.1e-06 28.9 0.0 0.00017 21.9 0.0 3.4 4 0 0 4 4 4 1 Autophagy-related protein C terminal domain PH_11 PF15413.6 OQR97695.1 - 0.0024 18.3 0.1 10 6.6 0.0 4.1 3 0 0 3 3 3 1 Pleckstrin homology domain Apt1 PF10351.9 OQR97695.1 - 0.0061 15.5 0.0 0.01 14.7 0.0 1.3 1 0 0 1 1 1 1 Golgi-body localisation protein domain PH_8 PF15409.6 OQR97695.1 - 0.076 13.3 0.0 2.1 8.7 0.0 3.0 3 0 0 3 3 3 0 Pleckstrin homology domain PDZ PF00595.24 OQR97695.1 - 0.083 13.3 0.0 0.18 12.2 0.0 1.5 1 0 0 1 1 1 0 PDZ domain Mito_carr PF00153.27 OQR97696.1 - 2e-65 216.8 4.0 6.1e-22 77.4 0.2 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Pkinase PF00069.25 OQR97697.1 - 4.2e-41 141.1 0.0 1.8e-40 139.0 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQR97697.1 - 2.3e-38 132.0 0.0 4.3e-38 131.1 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 OQR97697.1 - 0.00029 20.3 0.1 0.00044 19.7 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 OQR97697.1 - 0.002 17.1 0.0 0.034 13.1 0.0 2.0 1 1 1 2 2 2 2 Haspin like kinase domain Pkinase_fungal PF17667.1 OQR97697.1 - 0.014 14.2 0.1 0.021 13.6 0.1 1.1 1 0 0 1 1 1 0 Fungal protein kinase Kinase-like PF14531.6 OQR97697.1 - 0.023 14.0 0.0 0.041 13.2 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Choline_kinase PF01633.20 OQR97697.1 - 0.052 13.1 0.0 0.55 9.8 0.0 2.0 1 1 1 2 2 2 0 Choline/ethanolamine kinase Sid-5 PF17204.3 OQR97697.1 - 0.13 12.4 0.2 2.6 8.3 0.2 2.3 2 0 0 2 2 2 0 Sid-5 family Cellulase PF00150.18 OQR97700.1 - 2.5e-52 178.0 0.7 1.1e-25 90.7 0.1 2.1 2 0 0 2 2 2 2 Cellulase (glycosyl hydrolase family 5) DUF2844 PF11005.8 OQR97700.1 - 0.032 14.2 0.0 6.8 6.7 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2844) Clathrin_bdg PF15045.6 OQR97700.1 - 0.1 12.6 0.0 9 6.4 0.0 2.6 2 0 0 2 2 2 0 Clathrin-binding box of Aftiphilin, vesicle trafficking PRANC PF09372.10 OQR97700.1 - 1.2 9.5 3.1 69 3.9 0.0 3.5 4 0 0 4 4 4 0 PRANC domain Frag1 PF10277.9 OQR97701.1 - 3e-07 30.2 11.2 4.5e-07 29.6 11.1 1.5 1 1 0 1 1 1 1 Frag1/DRAM/Sfk1 family DUF4231 PF14015.6 OQR97701.1 - 0.0092 16.4 0.3 0.099 13.1 0.0 2.4 1 1 1 2 2 2 1 Protein of unknown function (DUF4231) Ni_hydr_CYTB PF01292.20 OQR97701.1 - 0.031 13.9 0.0 0.04 13.5 0.0 1.2 1 0 0 1 1 1 0 Prokaryotic cytochrome b561 Sigma_reg_N PF13800.6 OQR97701.1 - 0.036 14.3 3.4 0.35 11.2 0.8 2.9 3 1 0 3 3 3 0 Sigma factor regulator N-terminal RSN1_TM PF13967.6 OQR97701.1 - 0.095 12.5 1.6 0.23 11.2 1.6 1.7 1 1 0 1 1 1 0 Late exocytosis, associated with Golgi transport DUF5056 PF16479.5 OQR97701.1 - 0.097 12.9 0.5 0.22 11.8 0.2 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF5056) Cation_ATPase_C PF00689.21 OQR97701.1 - 0.19 11.4 3.4 0.21 11.3 1.4 1.9 1 1 0 2 2 2 0 Cation transporting ATPase, C-terminus DUF5313 PF17240.2 OQR97701.1 - 0.49 10.8 4.0 3.9 7.9 0.1 2.5 2 1 1 3 3 3 0 Family of unknown function (DUF5313) IQ PF00612.27 OQR97702.1 - 0.22 11.4 1.1 0.56 10.1 1.1 1.7 1 0 0 1 1 1 0 IQ calmodulin-binding motif Aminotran_5 PF00266.19 OQR97703.1 - 1.1e-69 235.2 1.2 3.8e-69 233.4 1.2 1.7 1 1 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 OQR97703.1 - 0.011 15.0 0.2 0.021 14.1 0.2 1.4 1 0 0 1 1 1 0 Beta-eliminating lyase ELMO_CED12 PF04727.13 OQR97704.1 - 3.8e-25 89.0 0.1 6e-25 88.4 0.1 1.2 1 0 0 1 1 1 1 ELMO/CED-12 family HAD_2 PF13419.6 OQR97705.1 - 1.5e-17 64.2 0.0 2e-17 63.9 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 OQR97705.1 - 1.4e-10 41.8 0.0 1.8e-10 41.5 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 OQR97705.1 - 8e-06 25.8 0.0 1.4e-05 25.0 0.0 1.3 1 0 0 1 1 1 1 HAD-hyrolase-like UCH PF00443.29 OQR97706.1 - 5e-37 127.8 2.3 1.8e-35 122.7 0.0 2.8 3 0 0 3 3 3 2 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 OQR97706.1 - 5.2e-18 65.7 0.1 1.9e-17 63.9 0.1 2.0 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase AAA_lid_7 PF17867.1 OQR97706.1 - 0.0046 17.2 0.8 0.3 11.3 0.0 3.8 3 0 0 3 3 3 1 Midasin AAA lid domain Popeye PF04831.13 OQR97706.1 - 0.079 13.1 0.0 0.25 11.5 0.0 1.8 1 0 0 1 1 1 0 Popeye protein conserved region WD40 PF00400.32 OQR97707.1 - 8.6e-10 39.1 28.6 0.021 15.7 0.5 7.8 8 0 0 8 8 8 5 WD domain, G-beta repeat WD40_like PF17005.5 OQR97707.1 - 0.00046 19.6 0.5 0.0015 18.0 0.2 1.9 2 0 0 2 2 2 1 WD40-like domain ADK PF00406.22 OQR97708.1 - 3.5e-89 296.6 0.0 3.2e-45 153.9 0.0 3.4 3 0 0 3 3 3 3 Adenylate kinase DUF4821 PF16092.5 OQR97708.1 - 2.1e-54 184.9 2.8 2.9e-54 184.5 2.8 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4821) AAA_17 PF13207.6 OQR97708.1 - 2.8e-50 170.3 0.3 1.9e-22 80.2 0.0 3.6 3 0 0 3 3 3 3 AAA domain AAA_18 PF13238.6 OQR97708.1 - 1.3e-13 51.7 0.0 3.8e-05 24.3 0.0 3.9 3 0 0 3 3 3 3 AAA domain AAA_33 PF13671.6 OQR97708.1 - 1.2e-12 48.2 0.2 0.0018 18.4 0.0 4.9 3 1 1 4 4 4 3 AAA domain Hydin_ADK PF17213.3 OQR97708.1 - 5e-09 36.7 12.8 0.16 12.3 0.0 5.5 5 1 1 6 6 6 3 Hydin Adenylate kinase-like domain Thymidylate_kin PF02223.17 OQR97708.1 - 8.7e-08 32.1 0.4 0.16 11.6 0.0 4.4 4 1 0 4 4 4 2 Thymidylate kinase Cytidylate_kin PF02224.18 OQR97708.1 - 0.00011 22.0 1.1 0.15 11.8 0.0 3.1 3 0 0 3 3 3 2 Cytidylate kinase Rad17 PF03215.15 OQR97708.1 - 0.00021 21.3 4.4 0.37 10.7 0.1 3.6 3 0 0 3 3 3 1 Rad17 P-loop domain AAA PF00004.29 OQR97708.1 - 0.0005 20.5 1.3 0.16 12.4 0.0 3.5 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 OQR97708.1 - 0.00053 20.3 0.3 0.64 10.3 0.0 3.7 3 0 0 3 3 3 1 AAA domain AAA_28 PF13521.6 OQR97708.1 - 0.0027 18.0 2.4 0.085 13.1 0.1 3.2 3 0 0 3 3 3 1 AAA domain MAF_flag10 PF01973.18 OQR97708.1 - 0.022 14.5 0.2 3.4 7.3 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function DUF115 ADK_lid PF05191.14 OQR97708.1 - 0.093 12.7 0.0 0.27 11.3 0.0 1.8 1 0 0 1 1 1 0 Adenylate kinase, active site lid AAA_16 PF13191.6 OQR97708.1 - 0.11 12.9 0.0 0.4 11.1 0.0 1.9 1 1 0 1 1 1 0 AAA ATPase domain TMEM65 PF10507.9 OQR97753.1 - 1.1e-40 138.0 2.8 1.6e-40 137.4 2.8 1.3 1 0 0 1 1 1 1 Transmembrane protein 65 TPR_8 PF13181.6 OQR97755.1 - 0.00061 19.8 1.7 0.46 10.8 0.0 4.4 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_11 PF13414.6 OQR97755.1 - 0.028 14.1 0.0 19 5.1 0.0 4.0 5 0 0 5 5 5 0 TPR repeat TPR_2 PF07719.17 OQR97755.1 - 0.24 11.6 1.7 63 4.0 0.1 4.5 5 0 0 5 5 5 0 Tetratricopeptide repeat Lectin_leg-like PF03388.13 OQR97756.1 - 2.8e-27 95.6 0.1 4.2e-27 95.0 0.1 1.2 1 0 0 1 1 1 1 Legume-like lectin family Bact_lectin PF18483.1 OQR97756.1 - 2.4e-13 50.5 1.1 4.6e-13 49.6 1.1 1.3 1 0 0 1 1 1 1 Bacterial lectin Lectin_legB PF00139.19 OQR97756.1 - 1.7e-06 27.8 0.1 4.4e-06 26.4 0.1 1.6 1 1 0 1 1 1 1 Legume lectin domain Gp-FAR-1 PF05823.12 OQR97756.1 - 0.00037 20.9 3.1 0.00072 19.9 3.1 1.4 1 0 0 1 1 1 1 Nematode fatty acid retinoid binding protein (Gp-FAR-1) RRP36 PF06102.12 OQR97756.1 - 0.021 14.8 3.0 0.033 14.2 3.0 1.2 1 0 0 1 1 1 0 rRNA biogenesis protein RRP36 DUF4366 PF14283.6 OQR97756.1 - 0.032 14.3 0.0 0.083 12.9 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) PLC-beta_C PF08703.10 OQR97756.1 - 0.054 13.5 7.3 0.079 12.9 7.3 1.2 1 0 0 1 1 1 0 PLC-beta C terminal OmpH PF03938.14 OQR97756.1 - 0.058 13.7 4.8 0.11 12.9 4.8 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) AAA_lid_9 PF17871.1 OQR97756.1 - 0.15 12.0 2.9 0.34 10.9 2.9 1.5 1 0 0 1 1 1 0 AAA lid domain CdvA PF18822.1 OQR97756.1 - 0.17 11.7 8.3 0.58 10.0 8.3 1.8 1 1 0 1 1 1 0 CdvA-like coiled-coil domain OrfB_IS605 PF01385.19 OQR97756.1 - 0.36 11.0 2.2 8.1 6.7 0.3 2.4 1 1 1 2 2 2 0 Probable transposase TMF_DNA_bd PF12329.8 OQR97756.1 - 0.41 10.7 6.5 0.23 11.5 3.1 2.2 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding DUF1690 PF07956.11 OQR97756.1 - 0.57 10.6 7.9 0.2 12.1 3.3 2.1 1 1 1 2 2 2 0 Protein of Unknown function (DUF1690) CLZ PF16526.5 OQR97756.1 - 1.4 9.3 6.1 3.6 8.0 2.6 2.3 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels SNF2_N PF00176.23 OQR97757.1 - 5.8e-61 206.1 0.0 9.4e-61 205.5 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 OQR97757.1 - 5.7e-06 26.6 0.1 2.5e-05 24.6 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Prok-RING_4 PF14447.6 OQR97757.1 - 0.0037 17.1 10.1 0.0091 15.8 10.1 1.7 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 ERCC3_RAD25_C PF16203.5 OQR97757.1 - 0.0042 16.3 0.0 0.0088 15.3 0.0 1.4 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase zf-C3HC4 PF00097.25 OQR97757.1 - 0.038 13.9 10.9 0.076 12.9 10.9 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 OQR97757.1 - 0.18 11.7 12.1 0.36 10.7 12.1 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) ResIII PF04851.15 OQR97757.1 - 0.2 11.7 0.0 1.3 9.0 0.0 2.1 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit zf-RING_5 PF14634.6 OQR97757.1 - 0.38 10.7 14.3 0.42 10.6 12.9 1.9 2 0 0 2 2 2 0 zinc-RING finger domain zf-RING_2 PF13639.6 OQR97757.1 - 1.9 8.9 13.6 4.7 7.6 13.6 1.7 1 0 0 1 1 1 0 Ring finger domain FYVE PF01363.21 OQR97757.1 - 2.3 8.4 7.5 5.4 7.2 7.5 1.6 1 0 0 1 1 1 0 FYVE zinc finger zf-RING_UBOX PF13445.6 OQR97757.1 - 5.6 7.1 12.2 14 5.9 12.2 1.7 1 0 0 1 1 1 0 RING-type zinc-finger MFS_1 PF07690.16 OQR97758.1 - 4.6e-10 39.0 11.7 5.4e-10 38.7 11.7 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 OQR97758.1 - 1.2 7.9 13.6 0.04 12.8 7.7 1.4 2 0 0 2 2 2 0 Sugar (and other) transporter FYVE PF01363.21 OQR97759.1 - 0.00056 20.0 9.5 0.0014 18.7 9.5 1.7 1 0 0 1 1 1 1 FYVE zinc finger START PF01852.19 OQR97759.1 - 0.01 15.3 0.0 0.016 14.6 0.0 1.4 1 0 0 1 1 1 0 START domain zf-C3HC4_3 PF13920.6 OQR97759.1 - 0.54 10.2 11.7 1.8 8.5 9.1 2.4 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Bap31_Bap29_C PF18035.1 OQR97760.1 - 3.1e-08 33.5 25.5 0.00056 19.8 5.7 3.4 2 1 1 3 3 3 3 Bap31/Bap29 cytoplasmic coiled-coil domain TolA_bind_tri PF16331.5 OQR97760.1 - 8.7e-06 25.7 6.2 0.24 11.5 0.5 3.1 3 0 0 3 3 3 2 TolA binding protein trimerisation Cnn_1N PF07989.11 OQR97760.1 - 0.00013 22.0 16.5 0.047 13.9 1.1 3.1 2 1 0 2 2 2 2 Centrosomin N-terminal motif 1 Med4 PF10018.9 OQR97760.1 - 0.00014 21.6 13.9 0.00067 19.4 14.0 1.9 1 1 0 1 1 1 1 Vitamin-D-receptor interacting Mediator subunit 4 EzrA PF06160.12 OQR97760.1 - 0.00025 19.4 18.0 0.0028 15.9 11.5 2.0 1 1 1 2 2 2 2 Septation ring formation regulator, EzrA BLOC1_2 PF10046.9 OQR97760.1 - 0.00026 21.2 18.1 0.037 14.3 3.5 2.3 1 1 1 2 2 2 2 Biogenesis of lysosome-related organelles complex-1 subunit 2 Filament PF00038.21 OQR97760.1 - 0.00029 20.5 15.1 0.035 13.7 7.5 2.0 1 1 1 2 2 2 2 Intermediate filament protein Baculo_PEP_C PF04513.12 OQR97760.1 - 0.00035 20.6 3.4 0.00035 20.6 3.4 1.7 2 0 0 2 2 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus FlxA PF14282.6 OQR97760.1 - 0.00038 20.4 19.6 0.0038 17.2 9.7 2.4 1 1 1 2 2 2 1 FlxA-like protein DUF3734 PF12536.8 OQR97760.1 - 0.0012 19.1 3.8 0.0016 18.7 1.7 2.0 1 1 1 2 2 2 1 Patatin phospholipase TMF_TATA_bd PF12325.8 OQR97760.1 - 0.0015 18.7 16.3 0.022 15.0 10.3 2.7 1 1 1 2 2 2 1 TATA element modulatory factor 1 TATA binding Csm1_N PF18504.1 OQR97760.1 - 0.0019 18.5 20.8 0.053 13.9 5.7 3.3 2 1 2 4 4 4 2 Csm1 N-terminal domain Spc7 PF08317.11 OQR97760.1 - 0.0021 17.0 21.4 0.012 14.5 13.9 2.0 1 1 1 2 2 2 2 Spc7 kinetochore protein IFT57 PF10498.9 OQR97760.1 - 0.0023 17.0 10.7 0.0023 17.0 10.7 2.0 1 1 1 2 2 2 1 Intra-flagellar transport protein 57 Lebercilin PF15619.6 OQR97760.1 - 0.0031 17.2 19.9 0.0085 15.8 19.4 2.0 1 1 0 1 1 1 1 Ciliary protein causing Leber congenital amaurosis disease GAS PF13851.6 OQR97760.1 - 0.0033 16.8 21.7 0.008 15.5 13.2 2.2 1 1 1 2 2 2 2 Growth-arrest specific micro-tubule binding FlaC_arch PF05377.11 OQR97760.1 - 0.0038 17.6 13.6 0.12 12.7 1.8 3.3 1 1 1 3 3 3 1 Flagella accessory protein C (FlaC) Phage_GP20 PF06810.11 OQR97760.1 - 0.0045 16.8 25.0 0.16 11.8 1.7 3.8 1 1 1 3 3 3 1 Phage minor structural protein GP20 APG6_N PF17675.1 OQR97760.1 - 0.005 17.4 25.5 0.091 13.3 6.9 2.6 1 1 1 2 2 2 1 Apg6 coiled-coil region HALZ PF02183.18 OQR97760.1 - 0.0069 16.6 21.9 0.13 12.5 1.4 3.9 4 1 0 4 4 3 1 Homeobox associated leucine zipper Pox_A_type_inc PF04508.12 OQR97760.1 - 0.0071 16.2 1.5 0.11 12.4 0.1 2.7 3 0 0 3 3 2 1 Viral A-type inclusion protein repeat CENP-F_leu_zip PF10473.9 OQR97760.1 - 0.0083 16.1 21.5 0.015 15.3 13.6 2.4 1 1 0 2 2 2 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF3584 PF12128.8 OQR97760.1 - 0.0088 13.6 14.1 0.01 13.4 14.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) DUF4140 PF13600.6 OQR97760.1 - 0.01 16.2 14.3 0.12 12.8 1.5 2.9 2 1 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) DUF4600 PF15372.6 OQR97760.1 - 0.012 16.0 14.8 0.7 10.3 0.6 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4600) TPR_MLP1_2 PF07926.12 OQR97760.1 - 0.012 15.6 17.5 0.012 15.6 17.5 2.2 1 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein HAUS5 PF14817.6 OQR97760.1 - 0.016 14.0 10.0 0.019 13.7 10.0 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 5 PspA_IM30 PF04012.12 OQR97760.1 - 0.017 14.7 22.3 0.06 12.9 2.1 2.8 1 1 1 2 2 2 0 PspA/IM30 family ATG16 PF08614.11 OQR97760.1 - 0.017 15.4 19.7 8.3 6.6 8.7 2.8 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) DUF948 PF06103.11 OQR97760.1 - 0.02 15.1 11.3 0.19 12.0 6.8 2.9 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF948) YabA PF06156.13 OQR97760.1 - 0.02 15.5 14.9 1.7 9.3 0.7 3.0 1 1 2 3 3 3 0 Initiation control protein YabA APG17 PF04108.12 OQR97760.1 - 0.024 13.7 11.6 0.1 11.7 11.6 1.8 1 1 0 1 1 1 0 Autophagy protein Apg17 UPF0242 PF06785.11 OQR97760.1 - 0.024 14.7 16.0 0.034 14.2 16.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus KASH_CCD PF14662.6 OQR97760.1 - 0.029 14.2 20.4 0.073 12.9 20.4 1.9 1 1 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH Hemerythrin PF01814.23 OQR97760.1 - 0.035 14.7 1.1 0.79 10.4 0.2 2.5 1 1 1 2 2 2 0 Hemerythrin HHE cation binding domain FliJ PF02050.16 OQR97760.1 - 0.035 14.3 14.3 0.078 13.2 0.6 2.7 2 1 0 2 2 2 0 Flagellar FliJ protein DHR10 PF18595.1 OQR97760.1 - 0.04 14.0 22.6 0.47 10.5 3.8 2.8 1 1 1 2 2 2 0 Designed helical repeat protein 10 domain Fez1 PF06818.15 OQR97760.1 - 0.042 14.3 13.1 0.061 13.8 13.1 1.2 1 0 0 1 1 1 0 Fez1 DUF4200 PF13863.6 OQR97760.1 - 0.043 14.2 19.6 0.8 10.1 2.1 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) Prefoldin_2 PF01920.20 OQR97760.1 - 0.046 13.7 23.3 0.31 11.0 4.6 3.2 2 1 1 3 3 3 0 Prefoldin subunit DUF4349 PF14257.6 OQR97760.1 - 0.047 13.1 12.3 0.096 12.1 3.3 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4349) DUF4618 PF15397.6 OQR97760.1 - 0.052 13.0 15.6 0.71 9.2 0.4 2.1 1 1 0 2 2 2 0 Domain of unknown function (DUF4618) Pox_A32 PF04665.12 OQR97760.1 - 0.054 12.9 1.1 0.083 12.3 1.1 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein DivIC PF04977.15 OQR97760.1 - 0.065 13.0 21.7 0.2 11.4 3.4 4.0 1 1 2 3 3 3 0 Septum formation initiator ADIP PF11559.8 OQR97760.1 - 0.065 13.3 20.7 0.054 13.6 7.8 3.0 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding MAD PF05557.13 OQR97760.1 - 0.076 11.4 18.8 0.11 10.9 11.4 1.8 1 1 0 1 1 1 0 Mitotic checkpoint protein Laminin_II PF06009.12 OQR97760.1 - 0.08 13.0 16.4 0.23 11.5 11.4 2.2 1 1 1 2 2 2 0 Laminin Domain II Cep57_CLD_2 PF14197.6 OQR97760.1 - 0.088 12.9 15.7 3.5 7.8 0.1 3.1 2 1 0 2 2 2 0 Centrosome localisation domain of PPC89 Seryl_tRNA_N PF02403.22 OQR97760.1 - 0.096 12.9 19.1 0.59 10.4 8.6 2.3 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Yuri_gagarin PF15934.5 OQR97760.1 - 0.098 12.5 8.8 0.14 12.0 8.8 1.2 1 0 0 1 1 1 0 Yuri gagarin GrpE PF01025.19 OQR97760.1 - 0.11 12.1 21.3 0.19 11.4 3.8 3.0 1 1 2 3 3 3 0 GrpE TSC22 PF01166.18 OQR97760.1 - 0.16 12.3 7.0 0.79 10.1 0.1 3.0 3 0 0 3 3 2 0 TSC-22/dip/bun family PRKG1_interact PF15898.5 OQR97760.1 - 0.17 12.8 19.7 0.08 13.8 12.1 2.9 1 1 2 3 3 3 0 cGMP-dependent protein kinase interacting domain JAKMIP_CC3 PF16034.5 OQR97760.1 - 0.19 11.7 15.9 1.9 8.4 15.9 2.0 1 1 0 1 1 1 0 JAKMIP CC3 domain DUF4407 PF14362.6 OQR97760.1 - 0.2 11.0 16.5 0.55 9.5 16.5 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) CwsA PF10814.8 OQR97760.1 - 0.22 11.7 2.0 0.35 11.1 1.8 1.4 1 1 0 1 1 1 0 Cell wall synthesis protein CwsA Prp19 PF08606.11 OQR97760.1 - 0.23 11.5 5.6 3.1 7.8 1.6 3.2 2 1 1 3 3 3 0 Prp19/Pso4-like Leu_zip PF15294.6 OQR97760.1 - 0.23 11.0 20.1 0.61 9.5 12.4 2.0 1 1 1 2 2 2 0 Leucine zipper DUF3138 PF11336.8 OQR97760.1 - 0.24 10.0 5.0 3.9 6.0 5.1 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF3138) PI3K_P85_iSH2 PF16454.5 OQR97760.1 - 0.25 10.9 15.3 2.6 7.6 2.1 2.9 1 1 0 1 1 1 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain Scaffolding_pro PF11418.8 OQR97760.1 - 0.27 11.8 6.3 0.38 11.3 1.1 2.3 1 1 1 2 2 2 0 Phi29 scaffolding protein SNCAIP_SNCA_bd PF16700.5 OQR97760.1 - 0.3 10.8 0.1 0.3 10.8 0.1 3.0 3 1 1 4 4 3 0 Synphilin-1 alpha-Synuclein-binding domain Spc24 PF08286.11 OQR97760.1 - 0.31 11.3 20.9 0.37 11.0 2.2 3.1 1 1 2 3 3 3 0 Spc24 subunit of Ndc80 SOGA PF11365.8 OQR97760.1 - 0.34 12.1 14.1 0.57 11.4 7.7 2.8 1 1 2 3 3 3 0 Protein SOGA Prefoldin PF02996.17 OQR97760.1 - 0.35 10.8 18.1 23 5.0 11.4 3.2 1 1 0 2 2 2 0 Prefoldin subunit TMF_DNA_bd PF12329.8 OQR97760.1 - 0.38 10.8 29.3 2.7 8.0 5.3 3.9 2 2 1 3 3 3 0 TATA element modulatory factor 1 DNA binding PV-1 PF06637.11 OQR97760.1 - 0.39 9.5 14.8 0.37 9.6 13.5 1.5 1 1 0 1 1 1 0 PV-1 protein (PLVAP) Cauli_AT PF03233.13 OQR97760.1 - 0.39 10.6 11.1 0.18 11.8 2.7 2.1 1 1 1 2 2 2 0 Aphid transmission protein WXG100 PF06013.12 OQR97760.1 - 0.49 10.7 10.3 0.43 10.8 3.5 2.3 1 1 0 2 2 2 0 Proteins of 100 residues with WXG Jnk-SapK_ap_N PF09744.9 OQR97760.1 - 0.51 10.6 20.2 1.2 9.3 13.7 2.3 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 DUF724 PF05266.14 OQR97760.1 - 0.51 10.1 16.9 0.48 10.2 13.2 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF724) Occludin_ELL PF07303.13 OQR97760.1 - 0.52 11.1 13.0 0.55 11.0 6.9 2.5 1 1 1 2 2 2 0 Occludin homology domain Ax_dynein_light PF10211.9 OQR97760.1 - 0.61 10.0 18.0 1.6 8.6 8.0 2.7 1 1 2 3 3 3 0 Axonemal dynein light chain Mod_r PF07200.13 OQR97760.1 - 0.62 10.2 21.8 4.1 7.5 19.8 2.6 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein LMBR1 PF04791.16 OQR97760.1 - 0.62 8.9 6.8 0.66 8.8 6.8 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein bZIP_1 PF00170.21 OQR97760.1 - 0.62 10.2 19.6 2.5 8.3 1.3 3.6 2 1 1 3 3 3 0 bZIP transcription factor DUF3450 PF11932.8 OQR97760.1 - 0.64 9.3 19.3 6.7 5.9 2.1 2.6 1 1 0 2 2 2 0 Protein of unknown function (DUF3450) COG5 PF10392.9 OQR97760.1 - 0.68 10.1 11.6 0.57 10.4 9.5 1.8 1 1 0 1 1 1 0 Golgi transport complex subunit 5 Snapin_Pallidin PF14712.6 OQR97760.1 - 0.82 10.1 15.3 0.82 10.1 1.0 3.0 1 1 2 3 3 3 0 Snapin/Pallidin CLZ PF16526.5 OQR97760.1 - 0.86 10.0 19.8 1.6 9.1 2.8 3.2 1 1 2 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DivIVA PF05103.13 OQR97760.1 - 0.91 9.6 17.8 0.92 9.6 13.0 2.7 1 1 1 2 2 2 0 DivIVA protein bZIP_Maf PF03131.17 OQR97760.1 - 0.93 10.1 15.5 1.5 9.4 1.1 3.0 2 1 1 3 3 3 0 bZIP Maf transcription factor Tropomyosin_1 PF12718.7 OQR97760.1 - 0.97 9.6 24.0 0.42 10.8 9.2 2.9 1 1 1 3 3 3 0 Tropomyosin like DASH_Hsk3 PF08227.11 OQR97760.1 - 0.98 9.8 12.9 0.39 11.1 2.3 3.3 4 0 0 4 4 3 0 DASH complex subunit Hsk3 like BCAS2 PF05700.11 OQR97760.1 - 1.1 8.9 11.9 3.4 7.3 8.7 2.5 1 1 1 2 2 2 0 Breast carcinoma amplified sequence 2 (BCAS2) ZapB PF06005.12 OQR97760.1 - 1.3 9.5 21.6 5.1 7.6 1.3 3.2 2 1 1 3 3 3 0 Cell division protein ZapB Sec34 PF04136.15 OQR97760.1 - 1.4 8.8 14.9 4.4 7.2 8.5 2.7 1 1 0 2 2 2 0 Sec34-like family FapA PF03961.13 OQR97760.1 - 1.5 7.3 16.1 0.19 10.3 9.4 1.9 1 1 1 2 2 2 0 Flagellar Assembly Protein A Swi5 PF07061.11 OQR97760.1 - 1.5 8.9 19.8 1.3 9.2 3.3 3.3 2 1 0 3 3 3 0 Swi5 LtuB PF17455.2 OQR97760.1 - 1.5 9.5 6.6 5.4 7.7 0.8 2.7 2 1 1 3 3 2 0 Late transcription unit B TMPIT PF07851.13 OQR97760.1 - 1.5 8.0 16.0 0.72 9.0 7.7 2.0 1 1 1 2 2 2 0 TMPIT-like protein DUF1664 PF07889.12 OQR97760.1 - 1.6 8.8 11.4 2.5 8.1 4.5 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) GTP-bdg_M PF16360.5 OQR97760.1 - 1.6 9.4 9.0 19 5.9 0.4 3.0 2 1 0 2 2 2 0 GTP-binding GTPase Middle Region DUF745 PF05335.13 OQR97760.1 - 1.8 8.3 18.5 0.54 10.0 14.6 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF745) DUF465 PF04325.13 OQR97760.1 - 1.8 8.7 14.1 2.5 8.2 0.9 3.8 4 1 0 4 4 3 0 Protein of unknown function (DUF465) DUF2730 PF10805.8 OQR97760.1 - 2.1 8.5 9.7 7.7 6.7 1.9 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF2730) THOC7 PF05615.13 OQR97760.1 - 2.2 8.6 14.8 3.1 8.1 14.3 1.5 1 1 0 1 1 1 0 Tho complex subunit 7 DUF2802 PF10975.8 OQR97760.1 - 2.3 8.4 11.7 0.53 10.4 1.3 3.3 3 1 0 3 3 3 0 Protein of unknown function (DUF2802) NPV_P10 PF05531.12 OQR97760.1 - 2.3 8.7 14.0 7.5 7.1 2.1 3.1 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein XhlA PF10779.9 OQR97760.1 - 2.3 8.5 14.2 4.6 7.5 1.0 3.5 2 1 2 4 4 4 0 Haemolysin XhlA DUF5595 PF18077.1 OQR97760.1 - 2.4 8.3 11.6 0.19 11.8 3.0 2.8 2 2 1 3 3 3 0 Domain of unknown function (DUF5595) PCRF PF03462.18 OQR97760.1 - 3.3 7.5 14.8 6.6 6.5 5.5 2.0 1 1 1 2 2 2 0 PCRF domain Fib_alpha PF08702.10 OQR97760.1 - 3.3 7.9 13.3 5.6 7.2 11.9 1.9 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Nnf1 PF03980.14 OQR97760.1 - 3.4 8.1 15.7 38 4.7 15.6 2.4 1 1 0 1 1 1 0 Nnf1 EMP24_GP25L PF01105.24 OQR97760.1 - 3.6 7.5 11.1 6.5 6.7 3.3 2.4 1 1 1 2 2 2 0 emp24/gp25L/p24 family/GOLD YscO PF07321.12 OQR97760.1 - 3.8 7.4 19.0 3.2 7.7 10.9 2.8 1 1 2 3 3 3 0 Type III secretion protein YscO SlyX PF04102.12 OQR97760.1 - 3.9 8.1 15.5 6.3 7.5 0.9 3.5 1 1 2 3 3 3 0 SlyX DUF812 PF05667.11 OQR97760.1 - 4 6.2 19.7 1.2 7.9 3.0 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF812) CCDC-167 PF15188.6 OQR97760.1 - 4.3 7.7 13.1 3.4 8.1 6.3 2.9 1 1 1 2 2 2 0 Coiled-coil domain-containing protein 167 DUF4795 PF16043.5 OQR97760.1 - 4.7 6.8 20.1 24 4.5 20.1 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) She9_MDM33 PF05546.11 OQR97760.1 - 4.7 7.0 13.4 9.2 6.0 6.5 2.6 1 1 1 2 2 2 0 She9 / Mdm33 family DUF2203 PF09969.9 OQR97760.1 - 4.8 7.9 11.2 7.9 7.2 6.1 2.4 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) DUF2937 PF11157.8 OQR97760.1 - 4.9 6.8 7.8 2.3 7.9 1.2 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2937) Atg14 PF10186.9 OQR97760.1 - 6.6 5.7 14.9 15 4.5 14.9 1.7 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 V_ATPase_I PF01496.19 OQR97760.1 - 8.1 4.2 13.0 2.8 5.7 7.4 1.9 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family bZIP_2 PF07716.15 OQR97760.1 - 9.7 6.4 15.3 1.6 8.9 1.6 3.9 4 1 0 4 4 4 0 Basic region leucine zipper Ank_2 PF12796.7 OQR97761.1 - 1e-15 58.0 0.1 7.5e-07 29.7 0.0 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 OQR97761.1 - 2.9e-14 52.8 0.1 8.5e-06 26.0 0.0 2.7 2 1 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.6 OQR97761.1 - 2.3e-13 50.4 0.1 2.1e-06 28.2 0.0 2.8 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 OQR97761.1 - 4.7e-13 49.1 0.2 6.7e-08 32.7 0.1 2.5 1 1 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQR97761.1 - 2.2e-12 46.0 0.4 6.5e-05 23.0 0.0 3.3 4 0 0 4 4 4 2 Ankyrin repeat Cullin PF00888.22 OQR97765.1 - 3.7e-198 660.0 15.9 4.6e-198 659.7 15.9 1.1 1 0 0 1 1 1 1 Cullin family Lipase_3 PF01764.25 OQR97765.1 - 7.6e-06 25.8 0.0 2.7e-05 24.0 0.0 2.0 2 0 0 2 2 2 1 Lipase (class 3) Cullin_Nedd8 PF10557.9 OQR97765.1 - 4.9e-05 23.3 0.9 0.00017 21.5 0.9 2.0 1 0 0 1 1 1 1 Cullin protein neddylation domain DUF2974 PF11187.8 OQR97765.1 - 0.08 12.5 1.3 8.6 5.8 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2974) PGAP1 PF07819.13 OQR97765.1 - 0.12 12.1 1.1 0.42 10.3 0.4 2.2 2 0 0 2 2 2 0 PGAP1-like protein UPF0227 PF05728.12 OQR97765.1 - 0.14 12.1 0.3 0.53 10.2 0.0 2.0 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0227) Methyltransf_31 PF13847.6 OQR97766.1 - 6e-07 29.4 0.4 2.6e-06 27.3 0.1 2.3 3 0 0 3 3 3 1 Methyltransferase domain ZZ PF00569.17 OQR97766.1 - 1.1e-06 28.3 12.1 1.1e-06 28.3 12.1 2.6 3 0 0 3 3 3 1 Zinc finger, ZZ type Methyltransf_25 PF13649.6 OQR97766.1 - 3.6e-06 27.6 0.0 8e-06 26.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OQR97766.1 - 3.8e-05 24.3 0.0 0.0001 23.0 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OQR97766.1 - 0.00055 19.8 0.0 0.0034 17.3 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OQR97766.1 - 0.00076 20.1 0.0 0.0019 18.8 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain zf-RING_2 PF13639.6 OQR97766.1 - 0.0013 19.1 1.3 0.0013 19.1 1.3 3.8 3 0 0 3 3 3 1 Ring finger domain PHD PF00628.29 OQR97766.1 - 0.0013 18.5 1.5 0.0013 18.5 1.5 3.8 4 1 0 4 4 4 1 PHD-finger MTS PF05175.14 OQR97766.1 - 0.002 17.7 0.0 0.0043 16.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_2 PF00891.18 OQR97766.1 - 0.019 14.3 0.0 0.057 12.7 0.0 1.7 2 0 0 2 2 2 0 O-methyltransferase domain LicD PF04991.13 OQR97767.1 - 2e-21 77.2 0.0 1.2e-20 74.6 0.0 2.0 1 1 0 1 1 1 1 LicD family PKD_channel PF08016.12 OQR97768.1 - 5.8e-12 45.0 7.2 5.8e-12 45.0 7.2 2.2 1 1 0 2 2 2 1 Polycystin cation channel Ion_trans PF00520.31 OQR97768.1 - 0.0052 16.1 21.1 0.036 13.3 21.1 2.2 1 1 0 1 1 1 1 Ion transport protein Baculo_11_kDa PF06143.11 OQR97768.1 - 0.075 12.6 4.1 1.5 8.4 0.4 2.7 2 0 0 2 2 2 0 Baculovirus 11 kDa family SieB PF14163.6 OQR97768.1 - 2.1 7.8 6.0 5.2 6.6 0.5 2.5 2 0 0 2 2 2 0 Super-infection exclusion protein B DUF4083 PF13314.6 OQR97768.1 - 2.4 8.2 5.8 0.4 10.7 0.5 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4083) MazG-like PF12643.7 OQR97769.1 - 6.7e-11 42.3 0.0 1.1e-10 41.6 0.0 1.3 1 0 0 1 1 1 1 MazG-like family MazG PF03819.17 OQR97769.1 - 4.1e-06 26.9 0.0 7.3e-06 26.1 0.0 1.4 1 0 0 1 1 1 1 MazG nucleotide pyrophosphohydrolase domain Cactin_mid PF10312.9 OQR97770.1 - 7.7e-57 192.2 4.8 3e-56 190.3 4.8 2.1 1 0 0 1 1 1 1 Conserved mid region of cactin CactinC_cactus PF09732.9 OQR97770.1 - 5.2e-40 136.3 2.9 1.3e-39 135.0 2.9 1.6 1 0 0 1 1 1 1 Cactus-binding C-terminus of cactin protein F-box-like PF12937.7 OQR97770.1 - 1.6e-10 40.7 0.4 1.3e-09 37.8 0.3 2.5 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 OQR97770.1 - 2.2e-05 24.2 0.2 9.2e-05 22.2 0.2 2.1 1 0 0 1 1 1 1 F-box domain Aldedh PF00171.22 OQR97771.1 - 5.1e-163 542.9 0.0 6.2e-163 542.6 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family PmbA_TldD PF01523.16 OQR97771.1 - 0.043 13.7 0.0 0.15 11.9 0.0 1.8 1 1 0 1 1 1 0 Putative modulator of DNA gyrase DUF1487 PF07368.11 OQR97771.1 - 0.068 12.6 0.0 1.3 8.4 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1487) GCS PF03074.16 OQR97772.1 - 1.1e-157 525.1 0.0 1.5e-157 524.7 0.0 1.2 1 0 0 1 1 1 1 Glutamate-cysteine ligase WD-3 PF09765.9 OQR97772.1 - 1.8e-64 217.9 0.0 3.4e-64 217.0 0.0 1.4 1 0 0 1 1 1 1 WD-repeat region FANCL_C PF11793.8 OQR97772.1 - 1.3e-26 92.6 3.2 1.3e-26 92.6 3.2 2.4 2 0 0 2 2 2 1 FANCL C-terminal domain zf-RING_2 PF13639.6 OQR97772.1 - 0.00017 21.9 5.0 0.00017 21.9 5.0 2.8 2 0 0 2 2 2 1 Ring finger domain zf-ANAPC11 PF12861.7 OQR97772.1 - 0.00061 19.8 0.5 0.0024 17.9 0.5 2.0 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger DUF2811 PF10929.8 OQR97772.1 - 0.15 12.3 0.0 1 9.7 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2811) zf-HC5HC2H PF13771.6 OQR97772.1 - 0.54 10.5 11.4 0.15 12.3 0.8 2.6 2 0 0 2 2 2 0 PHD-like zinc-binding domain Pkinase PF00069.25 OQR97774.1 - 8.4e-74 248.2 0.0 1.3e-73 247.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQR97774.1 - 5.8e-38 130.7 0.0 8.7e-38 130.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PH PF00169.29 OQR97774.1 - 8.6e-16 58.3 0.4 2.3e-15 57.0 0.4 1.8 1 0 0 1 1 1 1 PH domain EF-hand_7 PF13499.6 OQR97774.1 - 1.7e-06 28.4 0.3 0.016 15.7 0.2 3.0 2 1 0 2 2 2 2 EF-hand domain pair Kinase-like PF14531.6 OQR97774.1 - 4e-05 23.1 0.1 0.00077 18.9 0.0 2.2 1 1 0 2 2 2 1 Kinase-like EF-hand_6 PF13405.6 OQR97774.1 - 0.00014 21.5 0.7 0.0054 16.6 0.0 3.2 3 0 0 3 3 3 1 EF-hand domain EF-hand_1 PF00036.32 OQR97774.1 - 0.0003 20.1 3.9 0.00069 19.0 0.0 3.5 4 0 0 4 4 4 1 EF hand EF-hand_5 PF13202.6 OQR97774.1 - 0.0079 15.7 0.0 0.025 14.1 0.0 1.9 1 0 0 1 1 1 1 EF hand Kdo PF06293.14 OQR97774.1 - 0.082 12.3 0.0 0.17 11.2 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 OQR97774.1 - 0.13 11.9 0.7 1.5 8.4 0.0 2.4 2 1 0 3 3 3 0 Kinetochore Sim4 complex subunit FTA2 Pkinase_fungal PF17667.1 OQR97774.1 - 0.17 10.7 2.5 0.48 9.1 0.0 2.3 3 0 0 3 3 3 0 Fungal protein kinase NCBP3 PF10309.9 OQR97775.1 - 2.8e-14 52.7 0.0 5.9e-14 51.7 0.0 1.6 1 0 0 1 1 1 1 Nuclear cap-binding protein subunit 3 RNA_bind PF08675.11 OQR97775.1 - 0.00011 22.1 0.0 0.00027 20.9 0.0 1.5 1 0 0 1 1 1 1 RNA binding domain Tho1_MOS11_C PF18592.1 OQR97775.1 - 0.057 13.2 1.5 6.4 6.7 0.1 3.2 3 0 0 3 3 3 0 Tho1/MOS11 C-terminal domain Ank_2 PF12796.7 OQR97822.1 - 3.5e-06 27.5 5.4 0.0019 18.8 0.6 2.1 1 1 2 3 3 3 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OQR97822.1 - 0.0013 19.0 0.5 0.31 11.4 0.0 3.0 2 1 1 3 3 3 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQR97822.1 - 0.0016 18.8 1.1 2.2 9.1 0.0 4.2 4 0 0 4 4 4 1 Ankyrin repeat Ank_4 PF13637.6 OQR97822.1 - 0.0077 16.8 0.1 0.024 15.2 0.1 1.9 1 1 0 1 1 1 1 Ankyrin repeats (many copies) Thr_dehydrat_C PF00585.18 OQR97822.1 - 0.067 13.0 0.0 0.13 12.0 0.0 1.5 1 0 0 1 1 1 0 C-terminal regulatory domain of Threonine dehydratase DUF5049 PF16468.5 OQR97822.1 - 0.13 12.1 0.5 5.1 7.1 0.0 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF5049) DUF3539 PF12058.8 OQR97823.1 - 0.37 11.0 1.9 0.81 9.9 0.1 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3539) Seryl_tRNA_N PF02403.22 OQR97823.1 - 1.3 9.3 6.5 3.7 7.8 6.5 1.8 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain Picorna_P3A PF06363.11 OQR97824.1 - 0.011 15.6 0.0 0.024 14.5 0.0 1.5 1 0 0 1 1 1 0 Picornaviridae P3A protein EphA2_TM PF14575.6 OQR97824.1 - 0.024 15.5 0.4 0.096 13.6 0.0 2.1 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain AMP-binding PF00501.28 OQR97825.1 - 3.2e-87 292.9 0.1 6.3e-87 291.9 0.1 1.5 1 1 0 1 1 1 1 AMP-binding enzyme AMP-binding PF00501.28 OQR97826.1 - 8e-76 255.3 0.0 1.1e-75 254.9 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme PP-binding PF00550.25 OQR97826.1 - 2.7e-08 34.0 0.0 7.3e-08 32.6 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site MMM1 PF10296.9 OQR97827.1 - 0.2 10.7 0.0 0.2 10.7 0.0 2.4 3 0 0 3 3 3 0 Maintenance of mitochondrial morphology protein 1 Romo1 PF10247.9 OQR97827.1 - 1.1 9.7 7.9 0.46 10.9 3.0 2.3 2 0 0 2 2 2 0 Reactive mitochondrial oxygen species modulator 1 Methyltransf_16 PF10294.9 OQR97828.1 - 3.3e-32 111.6 0.1 4.2e-32 111.3 0.1 1.1 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_23 PF13489.6 OQR97828.1 - 0.0057 16.5 0.0 0.0075 16.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 OQR97828.1 - 0.0072 15.9 0.1 0.016 14.8 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_25 PF13649.6 OQR97828.1 - 0.054 14.2 0.0 0.11 13.2 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.12 OQR97828.1 - 0.11 13.3 0.0 0.29 11.9 0.0 1.7 1 1 1 2 2 2 0 Methyltransferase domain Methyltransf_31 PF13847.6 OQR97828.1 - 0.16 11.7 1.8 1 9.1 1.8 2.1 1 1 0 1 1 1 0 Methyltransferase domain DUF4586 PF15239.6 OQR97829.1 - 0.0075 16.5 0.9 0.011 15.9 0.6 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF4586) Pkinase PF00069.25 OQR97830.1 - 2.3e-29 102.6 0.1 3.2e-29 102.1 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQR97830.1 - 5.2e-27 94.8 0.3 6.8e-27 94.4 0.3 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OQR97830.1 - 0.00029 20.3 0.0 0.00042 19.7 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 OQR97830.1 - 0.0021 17.1 0.0 0.0031 16.5 0.0 1.3 1 0 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 OQR97830.1 - 0.0032 16.3 0.0 0.005 15.7 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 OQR97830.1 - 0.0046 16.9 0.8 0.007 16.3 0.8 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 OQR97830.1 - 0.015 14.6 0.4 0.024 14.0 0.4 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 OQR97830.1 - 0.084 12.5 0.0 0.15 11.7 0.0 1.4 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Vint PF14623.6 OQR97830.1 - 0.086 12.6 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 Hint-domain Fcf1 PF04900.12 OQR97831.1 - 8.6e-39 131.9 2.5 8.6e-39 131.9 2.5 1.7 2 0 0 2 2 2 1 Fcf1 PIN_9 PF18477.1 OQR97831.1 - 2.1e-11 44.2 0.1 4.4e-11 43.1 0.0 1.6 2 0 0 2 2 2 1 PIN like domain CUE PF02845.16 OQR97832.1 - 7e-09 35.2 0.3 1.2e-08 34.5 0.3 1.4 1 0 0 1 1 1 1 CUE domain GYF PF02213.16 OQR97833.1 - 2.8e-09 36.5 0.4 6.1e-09 35.4 0.4 1.6 1 0 0 1 1 1 1 GYF domain Flagellin_N PF00669.20 OQR97833.1 - 0.012 15.8 0.4 0.024 14.8 0.4 1.5 1 0 0 1 1 1 0 Bacterial flagellin N-terminal helical region TC1 PF15063.6 OQR97833.1 - 2.3 8.2 5.2 5.1 7.0 0.1 3.1 2 1 1 3 3 3 0 Thyroid cancer protein 1 RNA_ligase PF09414.10 OQR97834.1 - 2.5e-18 66.9 0.3 4.3e-18 66.1 0.3 1.4 1 0 0 1 1 1 1 RNA ligase PITH PF06201.13 OQR97835.1 - 3.7e-37 127.9 0.0 5.8e-37 127.2 0.0 1.3 1 0 0 1 1 1 1 PITH domain DUF4600 PF15372.6 OQR97836.1 - 0.0016 18.9 5.3 0.0019 18.6 5.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4600) FPP PF05911.11 OQR97836.1 - 0.0036 15.6 4.9 0.004 15.4 4.9 1.1 1 0 0 1 1 1 1 Filament-like plant protein, long coiled-coil Tropomyosin PF00261.20 OQR97836.1 - 0.0038 16.6 4.3 0.0044 16.4 4.3 1.1 1 0 0 1 1 1 1 Tropomyosin FliJ PF02050.16 OQR97836.1 - 0.0068 16.6 5.7 0.009 16.2 5.7 1.2 1 0 0 1 1 1 1 Flagellar FliJ protein SOGA PF11365.8 OQR97836.1 - 0.012 16.7 4.1 0.019 16.1 4.1 1.3 1 0 0 1 1 1 0 Protein SOGA SidC_N PF18219.1 OQR97836.1 - 0.054 12.5 1.2 0.06 12.3 1.2 1.0 1 0 0 1 1 1 0 SidC N-terminal domain FAP206 PF12018.8 OQR97836.1 - 0.093 12.2 3.6 0.12 11.9 3.6 1.1 1 0 0 1 1 1 0 Domain of unknown function TMPIT PF07851.13 OQR97836.1 - 0.098 11.9 2.7 0.11 11.7 2.7 1.0 1 0 0 1 1 1 0 TMPIT-like protein FH2 PF02181.23 OQR97836.1 - 0.12 11.4 3.0 0.15 11.1 3.0 1.1 1 0 0 1 1 1 0 Formin Homology 2 Domain MAP65_ASE1 PF03999.12 OQR97836.1 - 0.19 10.4 7.3 0.1 11.3 5.7 1.3 1 1 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) DUF3450 PF11932.8 OQR97836.1 - 0.22 10.8 6.6 0.33 10.2 6.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Uso1_p115_C PF04871.13 OQR97836.1 - 0.26 11.7 6.1 0.34 11.3 6.1 1.1 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region OmpH PF03938.14 OQR97836.1 - 0.28 11.5 5.1 0.34 11.2 5.1 1.1 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Rho_Binding PF08912.11 OQR97836.1 - 0.49 11.2 7.6 0.83 10.5 7.6 1.4 1 0 0 1 1 1 0 Rho Binding DUF812 PF05667.11 OQR97836.1 - 0.53 9.1 7.6 0.62 8.9 7.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) CREPT PF16566.5 OQR97836.1 - 0.66 10.1 6.6 0.87 9.8 6.6 1.1 1 0 0 1 1 1 0 Cell-cycle alteration and expression-elevated protein in tumour FapA PF03961.13 OQR97836.1 - 2.8 6.5 4.8 3.4 6.2 4.8 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A rve PF00665.26 OQR97894.1 - 1.2e-10 41.6 0.0 3.2e-10 40.2 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 OQR97894.1 - 1.6e-10 40.9 0.2 4.7e-10 39.4 0.2 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain Chromo PF00385.24 OQR97894.1 - 5.9e-08 32.5 0.2 1.4e-07 31.3 0.2 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Anoctamin PF04547.12 OQR97895.1 - 1.3e-86 291.3 9.8 1.6e-86 291.0 9.8 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel PIP5K PF01504.18 OQR97897.1 - 8.9e-73 244.9 0.0 1.3e-72 244.4 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase 7tm_2 PF00002.24 OQR97897.1 - 6.5e-05 22.3 10.4 0.00014 21.3 9.7 1.9 1 1 0 1 1 1 1 7 transmembrane receptor (Secretin family) 7tm_1 PF00001.21 OQR97897.1 - 0.012 14.9 13.4 0.11 11.8 13.2 2.4 1 1 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) PDZ_6 PF17820.1 OQR97906.1 - 1.2e-13 50.6 0.6 0.00016 21.5 0.0 4.6 4 0 0 4 4 4 3 PDZ domain GRASP55_65 PF04495.14 OQR97906.1 - 5.6e-09 36.4 0.0 0.1 12.9 0.0 4.2 3 1 0 3 3 3 3 GRASP55/65 PDZ-like domain PDZ_2 PF13180.6 OQR97906.1 - 5.8e-09 36.2 0.0 0.013 15.9 0.0 4.0 4 0 0 4 4 4 2 PDZ domain PDZ PF00595.24 OQR97906.1 - 7.2e-06 26.3 0.1 7 7.1 0.0 4.5 5 0 0 5 5 5 3 PDZ domain DHHC PF01529.20 OQR97907.1 - 4.2e-24 85.2 6.5 4.2e-24 85.2 6.5 2.0 2 0 0 2 2 2 1 DHHC palmitoyltransferase C1_1 PF00130.22 OQR97907.1 - 0.032 14.1 4.8 0.032 14.1 4.8 1.7 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) DUF999 PF06198.11 OQR97907.1 - 0.11 12.5 0.1 0.22 11.5 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF999) Par3_HAL_N_term PF12053.8 OQR97908.1 - 0.00068 19.8 0.0 0.00085 19.5 0.0 1.1 1 0 0 1 1 1 1 N-terminal of Par3 and HAL proteins Pkinase PF00069.25 OQR97909.1 - 9.3e-52 176.0 0.0 1e-51 175.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQR97909.1 - 9.1e-32 110.3 0.0 1.2e-31 110.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OQR97909.1 - 7.2e-05 21.7 0.0 9.7e-05 21.3 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 OQR97909.1 - 0.0001 21.4 1.0 0.00016 20.7 1.0 1.4 1 1 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 OQR97909.1 - 0.00022 20.6 0.2 0.00037 19.9 0.2 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 OQR97909.1 - 0.01 15.1 0.0 0.015 14.7 0.0 1.2 1 0 0 1 1 1 0 Kinase-like APH PF01636.23 OQR97909.1 - 0.028 14.3 0.2 0.043 13.7 0.2 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family RIO1 PF01163.22 OQR97909.1 - 0.12 11.9 0.0 0.24 11.0 0.0 1.4 1 0 0 1 1 1 0 RIO1 family Filament PF00038.21 OQR97910.1 - 8.4e-18 65.0 53.6 8.4e-18 65.0 53.6 4.9 2 2 0 2 2 2 1 Intermediate filament protein LTD PF00932.19 OQR97910.1 - 6.3e-10 39.4 0.0 1.3e-09 38.3 0.0 1.5 1 0 0 1 1 1 1 Lamin Tail Domain DUF1084 PF06454.11 OQR97910.1 - 0.0086 15.5 13.0 0.022 14.1 13.0 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF1084) T7SS_ESX_EspC PF10824.8 OQR97911.1 - 0.11 13.0 10.1 31 5.1 0.4 5.7 6 0 0 6 6 6 0 Excreted virulence factor EspC, type VII ESX diderm Fasciclin PF02469.22 OQR97911.1 - 0.22 11.7 7.4 5.8 7.2 0.3 3.9 3 0 0 3 3 3 0 Fasciclin domain Peptidase_C2 PF00648.21 OQR97947.1 - 1.7e-40 138.9 0.0 1.1e-38 132.9 0.0 2.3 2 0 0 2 2 2 2 Calpain family cysteine protease Calpain_III PF01067.22 OQR97947.1 - 5.8e-09 36.3 0.0 1.9e-08 34.7 0.0 2.0 1 0 0 1 1 1 1 Calpain large subunit, domain III DZR PF12773.7 OQR97947.1 - 1.7e-07 31.1 4.7 1.7e-07 31.1 4.7 4.7 2 1 2 4 4 4 1 Double zinc ribbon zinc_ribbon_2 PF13240.6 OQR97947.1 - 0.0017 18.0 3.9 0.0017 18.0 3.9 6.0 6 1 1 7 7 7 2 zinc-ribbon domain zf-ribbon_3 PF13248.6 OQR97947.1 - 0.0032 16.8 0.6 0.0032 16.8 0.6 4.6 5 0 0 5 5 5 2 zinc-ribbon domain Vps36-NZF-N PF16988.5 OQR97947.1 - 4.8 6.6 6.5 21 4.6 0.2 3.8 3 0 0 3 3 3 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain EPSP_synthase PF00275.20 OQR97948.1 - 2.1e-120 402.2 0.0 3.1e-120 401.7 0.0 1.3 1 0 0 1 1 1 1 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) DHQ_synthase PF01761.20 OQR97948.1 - 6.9e-99 330.3 0.2 2.8e-98 328.3 0.1 2.0 2 0 0 2 2 2 1 3-dehydroquinate synthase DHquinase_I PF01487.15 OQR97948.1 - 4.6e-34 118.6 0.0 1.3e-33 117.2 0.0 1.8 1 1 0 1 1 1 1 Type I 3-dehydroquinase SKI PF01202.22 OQR97948.1 - 9.4e-31 107.1 0.0 7.9e-29 100.8 0.0 2.4 2 0 0 2 2 2 1 Shikimate kinase Shikimate_dh_N PF08501.11 OQR97948.1 - 2.1e-23 82.3 0.0 8e-23 80.5 0.0 2.1 2 0 0 2 2 2 1 Shikimate dehydrogenase substrate binding domain Fe-ADH_2 PF13685.6 OQR97948.1 - 9.4e-10 38.6 1.4 7.3e-09 35.7 1.4 2.4 1 1 0 1 1 1 1 Iron-containing alcohol dehydrogenase SDH_C PF18317.1 OQR97948.1 - 2.9e-08 33.3 0.0 6.8e-08 32.1 0.0 1.7 1 0 0 1 1 1 1 Shikimate 5'-dehydrogenase C-terminal domain Fe-ADH PF00465.19 OQR97948.1 - 1.9e-06 27.0 1.3 1.3e-05 24.2 1.3 2.1 1 1 0 1 1 1 1 Iron-containing alcohol dehydrogenase Shikimate_DH PF01488.20 OQR97948.1 - 1.3e-05 25.3 0.0 3.4e-05 23.9 0.0 1.7 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase AlaDh_PNT_C PF01262.21 OQR97948.1 - 0.0051 16.1 0.1 0.49 9.7 0.0 2.5 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain AAA_33 PF13671.6 OQR97948.1 - 0.0074 16.5 0.0 0.021 15.0 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 OQR97948.1 - 0.01 16.2 0.0 0.029 14.7 0.0 1.8 1 1 0 1 1 1 0 AAA ATPase domain NAD_binding_2 PF03446.15 OQR97948.1 - 0.011 15.9 0.0 0.041 14.1 0.0 1.9 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase AAA_18 PF13238.6 OQR97948.1 - 0.044 14.3 0.0 0.084 13.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain ADK PF00406.22 OQR97949.1 - 5.9e-13 49.2 0.0 2.6e-09 37.4 0.0 3.3 3 1 0 3 3 3 2 Adenylate kinase AAA_17 PF13207.6 OQR97949.1 - 6.7e-09 36.3 0.0 3.7e-05 24.2 0.0 3.4 3 1 0 3 3 3 2 AAA domain AAA_18 PF13238.6 OQR97949.1 - 6.6e-05 23.5 0.0 0.00032 21.2 0.0 2.1 2 0 0 2 2 2 1 AAA domain Hydin_ADK PF17213.3 OQR97949.1 - 0.00041 20.7 0.0 0.0013 19.1 0.0 1.8 1 0 0 1 1 1 1 Hydin Adenylate kinase-like domain AAA_33 PF13671.6 OQR97949.1 - 0.00084 19.5 0.0 0.54 10.4 0.0 2.8 2 0 0 2 2 2 2 AAA domain YHS PF04945.13 OQR97949.1 - 0.002 18.2 0.0 4.7 7.4 0.0 3.6 4 0 0 4 4 4 2 YHS domain AAA_14 PF13173.6 OQR97949.1 - 0.014 15.4 0.0 4.7 7.3 0.0 2.5 2 0 0 2 2 2 0 AAA domain FAP206 PF12018.8 OQR97949.1 - 0.079 12.5 0.0 2.8 7.4 0.0 3.1 3 0 0 3 3 3 0 Domain of unknown function AAA_24 PF13479.6 OQR97949.1 - 0.18 11.5 0.0 0.37 10.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 OQR97949.1 - 0.18 12.1 0.7 2.4 8.4 0.0 3.1 4 0 0 4 4 4 0 AAA domain Sugar_tr PF00083.24 OQR97950.1 - 5.6e-48 163.9 3.8 2.9e-33 115.4 0.2 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 OQR97950.1 - 4.1e-10 39.1 12.8 3.1e-05 23.1 3.9 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily WBS28 PF15164.6 OQR97950.1 - 0.016 14.5 0.1 0.022 14.1 0.1 1.1 1 0 0 1 1 1 0 Williams-Beuren syndrome chromosomal region 28 protein homologue DUF2157 PF09925.9 OQR97950.1 - 0.032 14.0 4.0 0.49 10.2 0.4 2.8 3 0 0 3 3 3 0 Predicted membrane protein (DUF2157) zf-RNPHF PF08080.12 OQR97950.1 - 0.17 11.9 0.6 0.32 11.0 0.6 1.4 1 0 0 1 1 1 0 RNPHF zinc finger Sugar_tr PF00083.24 OQR97951.1 - 1.7e-129 432.6 39.5 1.6e-105 353.6 26.4 2.0 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 OQR97951.1 - 3.7e-25 88.6 54.5 4.4e-18 65.3 12.0 3.4 1 1 2 3 3 3 3 Major Facilitator Superfamily TSCPD PF12637.7 OQR97951.1 - 0.44 10.8 2.0 15 5.9 0.1 2.6 2 0 0 2 2 2 0 TSCPD domain PseudoU_synth_2 PF00849.22 OQR97978.1 - 2.2e-31 109.1 0.3 4.8e-31 108.0 0.0 1.7 2 0 0 2 2 2 1 RNA pseudouridylate synthase Peptidase_S49_N PF08496.10 OQR97978.1 - 0.13 12.3 1.4 0.27 11.3 1.4 1.5 1 0 0 1 1 1 0 Peptidase family S49 N-terminal zf-TFIIB PF13453.6 OQR97978.1 - 0.44 9.9 1.9 12 5.3 1.9 2.7 1 1 0 1 1 1 0 Transcription factor zinc-finger RP853 PF17542.2 OQR97979.1 - 0.2 10.8 0.0 0.24 10.5 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized RP853 Motile_Sperm PF00635.26 OQR97980.1 - 7.4e-27 93.4 0.7 4.4e-13 49.0 0.2 3.6 3 0 0 3 3 3 3 MSP (Major sperm protein) domain Pkinase PF00069.25 OQR97981.1 - 3.6e-14 52.8 0.0 4.5e-12 45.9 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OQR97981.1 - 3e-09 36.6 0.0 1.2e-07 31.3 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.23 OQR97981.1 - 0.0004 20.4 0.0 0.00069 19.6 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 OQR97981.1 - 0.064 12.2 0.0 0.13 11.2 0.0 1.4 1 0 0 1 1 1 0 Haspin like kinase domain Protocadherin PF08374.11 OQR97981.1 - 0.13 12.2 0.0 0.21 11.5 0.0 1.2 1 0 0 1 1 1 0 Protocadherin Kin17_mid PF10357.9 OQR97981.1 - 0.15 11.9 0.1 0.29 11.0 0.1 1.4 1 0 0 1 1 1 0 Domain of Kin17 curved DNA-binding protein DUF4870 PF09685.10 OQR97981.1 - 0.43 10.7 3.6 0.19 11.8 0.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4870) WW PF00397.26 OQR97982.1 - 0.00044 20.3 0.0 0.00057 19.9 0.0 1.2 1 0 0 1 1 1 1 WW domain Pkinase PF00069.25 OQR97983.1 - 8.8e-64 215.4 0.5 1.7e-63 214.4 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQR97983.1 - 1.1e-50 172.3 0.0 1.9e-50 171.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase DUF3342 PF11822.8 OQR97983.1 - 3e-28 97.9 0.6 6.3e-28 96.8 0.6 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3342) Kinase-like PF14531.6 OQR97983.1 - 3.3e-06 26.6 0.2 1.5e-05 24.5 0.0 2.0 2 0 0 2 2 2 1 Kinase-like BTB PF00651.31 OQR97983.1 - 8.1e-06 26.0 0.1 3.8e-05 23.9 0.1 2.2 2 0 0 2 2 2 1 BTB/POZ domain Pkinase_fungal PF17667.1 OQR97983.1 - 0.023 13.5 0.9 0.054 12.3 0.0 1.9 2 0 0 2 2 2 0 Fungal protein kinase Recep_L_domain PF01030.24 OQR97983.1 - 0.064 13.4 0.0 0.22 11.7 0.0 1.8 1 0 0 1 1 1 0 Receptor L domain Pkinase PF00069.25 OQR97984.1 - 1.6e-56 191.6 0.0 2.8e-56 190.8 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain PP2C PF00481.21 OQR97984.1 - 9e-46 156.6 0.0 1.7e-45 155.7 0.0 1.5 1 0 0 1 1 1 1 Protein phosphatase 2C Pkinase_Tyr PF07714.17 OQR97984.1 - 1.7e-36 125.9 0.0 2.5e-36 125.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OQR97984.1 - 1.6e-06 27.6 0.0 3.1e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 OQR97984.1 - 0.0042 15.9 0.0 0.0042 15.9 0.0 2.1 3 0 0 3 3 3 1 Fungal protein kinase Seadorna_VP7 PF07387.11 OQR97984.1 - 0.011 14.8 0.2 0.021 13.9 0.2 1.4 1 0 0 1 1 1 0 Seadornavirus VP7 APH PF01636.23 OQR97984.1 - 0.18 11.7 0.1 0.99 9.3 0.1 1.9 1 1 0 2 2 2 0 Phosphotransferase enzyme family CAP_N PF01213.19 OQR97984.1 - 0.67 9.4 9.1 1.1 8.7 0.6 2.4 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal DUF2238 PF09997.9 OQR97985.1 - 0.0041 16.9 0.8 0.0041 16.9 0.8 1.9 2 0 0 2 2 2 1 Predicted membrane protein (DUF2238) CPBP PF02517.16 OQR97985.1 - 0.26 11.7 10.8 0.052 13.9 1.4 2.2 2 0 0 2 2 2 0 CPBP intramembrane metalloprotease DUF1286 PF06939.11 OQR97985.1 - 2.3 8.5 9.1 1.6 9.0 0.9 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1286) Choline_transpo PF04515.12 OQR97985.1 - 2.5 7.2 15.8 0.014 14.6 4.4 2.0 2 0 0 2 2 2 0 Plasma-membrane choline transporter C2 PF00168.30 OQR97986.1 - 6.7e-15 55.3 0.0 1.1e-14 54.6 0.0 1.4 1 0 0 1 1 1 1 C2 domain EndIII_4Fe-2S PF10576.9 OQR97987.1 - 1.9 8.9 15.8 0.097 13.0 1.2 5.8 4 0 0 4 4 4 0 Iron-sulfur binding domain of endonuclease III Guanylate_cyc PF00211.20 OQR97989.1 - 1.4e-13 50.9 0.0 1e-10 41.6 0.0 2.4 2 0 0 2 2 2 2 Adenylate and Guanylate cyclase catalytic domain Mitofilin PF09731.9 OQR97990.1 - 8.7e-37 127.3 0.6 9.6e-37 127.1 0.6 1.0 1 0 0 1 1 1 1 Mitochondrial inner membrane protein Pkinase PF00069.25 OQR97992.1 - 1.1e-73 247.9 0.0 1.3e-73 247.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQR97992.1 - 4e-41 141.0 0.0 5.3e-41 140.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OQR97992.1 - 1.9e-09 37.2 0.0 2.8e-09 36.7 0.0 1.4 1 1 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 OQR97992.1 - 1.4e-06 27.4 0.0 1.7e-06 27.1 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 OQR97992.1 - 0.00076 19.5 0.1 0.0023 17.9 0.1 1.7 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 OQR97992.1 - 0.003 16.9 0.3 0.0064 15.9 0.1 1.7 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 OQR97992.1 - 0.0054 16.3 0.1 0.012 15.2 0.1 1.7 1 0 0 1 1 1 1 RIO1 family Haspin_kinase PF12330.8 OQR97992.1 - 0.0068 15.4 0.1 0.013 14.5 0.1 1.6 1 1 0 1 1 1 1 Haspin like kinase domain Pkinase_C PF00433.24 OQR97992.1 - 0.016 15.9 0.6 0.032 14.9 0.6 1.5 1 0 0 1 1 1 0 Protein kinase C terminal domain FTA2 PF13095.6 OQR97992.1 - 0.028 14.0 0.0 4.7 6.8 0.0 2.3 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Gag_p19 PF02228.16 OQR97992.1 - 0.14 12.6 0.0 0.28 11.7 0.0 1.4 1 0 0 1 1 1 0 Major core protein p19 DUF5448 PF17526.2 OQR97992.1 - 0.16 12.1 0.0 0.36 11.0 0.0 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5448) Ribosom_S12_S23 PF00164.25 OQR97993.1 - 1.9e-50 169.3 0.6 2.4e-50 168.9 0.6 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 Ras PF00071.22 OQR97994.1 - 1.7e-46 157.8 0.9 3.4e-46 156.8 0.4 1.8 2 0 0 2 2 2 1 Ras family Ank_2 PF12796.7 OQR97994.1 - 8.2e-41 138.5 23.9 6.4e-11 42.7 0.7 7.4 2 2 4 7 7 7 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQR97994.1 - 1.5e-32 111.5 17.7 3.4e-07 30.7 0.2 11.1 5 3 5 10 10 10 8 Ankyrin repeats (many copies) Roc PF08477.13 OQR97994.1 - 3.7e-30 104.6 0.6 3.1e-28 98.4 0.1 2.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Ank_3 PF13606.6 OQR97994.1 - 3.5e-23 79.2 18.4 0.033 14.7 0.0 11.4 12 0 0 12 12 11 6 Ankyrin repeat Ank_5 PF13857.6 OQR97994.1 - 1.3e-21 76.4 15.5 2e-05 24.8 0.3 8.0 6 2 2 8 8 8 5 Ankyrin repeats (many copies) Ank PF00023.30 OQR97994.1 - 2.5e-17 62.5 32.7 0.074 13.5 0.0 10.9 12 0 0 12 12 11 6 Ankyrin repeat Arf PF00025.21 OQR97994.1 - 1.2e-11 44.4 0.2 2.5e-11 43.3 0.2 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 OQR97994.1 - 0.00023 20.6 0.2 0.00049 19.5 0.2 1.5 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 OQR97994.1 - 0.00037 20.1 1.1 0.002 17.7 1.1 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 OQR97994.1 - 0.0008 19.5 0.0 0.0026 17.8 0.0 2.0 1 0 0 1 1 1 1 50S ribosome-binding GTPase PduV-EutP PF10662.9 OQR97994.1 - 0.0066 16.2 1.0 0.024 14.4 0.1 2.2 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation FeoB_N PF02421.18 OQR97994.1 - 0.18 11.3 3.4 2.2 7.8 3.4 2.3 1 1 0 1 1 1 0 Ferrous iron transport protein B FAM221 PF14753.6 OQR97995.1 - 1.1e-33 116.5 19.2 1.7e-33 115.9 19.2 1.2 1 0 0 1 1 1 1 Protein FAM221A/B CDC27 PF09507.10 OQR97995.1 - 0.15 11.4 6.2 0.21 10.9 6.2 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Ceramidase PF05875.12 OQR97996.1 - 3e-47 161.3 20.1 3.7e-47 161.0 20.1 1.1 1 0 0 1 1 1 1 Ceramidase C2 PF00168.30 OQR97997.1 - 3e-16 59.6 0.0 4.8e-16 58.9 0.0 1.3 1 0 0 1 1 1 1 C2 domain SH3_9 PF14604.6 OQR97998.1 - 4.7e-24 84.0 4.2 8.6e-14 51.1 0.5 2.9 3 0 0 3 3 3 2 Variant SH3 domain SH3_1 PF00018.28 OQR97998.1 - 6.9e-20 70.4 0.3 7.3e-12 44.7 0.0 3.0 3 0 0 3 3 3 2 SH3 domain SH3_2 PF07653.17 OQR97998.1 - 3.8e-15 55.3 0.0 9.8e-07 28.4 0.0 2.6 2 0 0 2 2 2 2 Variant SH3 domain RNase_T PF00929.24 OQR97998.1 - 5.8e-08 33.5 0.6 1.5e-06 28.9 0.0 2.9 2 0 0 2 2 2 1 Exonuclease CAF1 PF04857.20 OQR97998.1 - 0.1 11.8 0.1 0.1 11.8 0.1 2.9 2 1 0 2 2 2 0 CAF1 family ribonuclease TrkA_C PF02080.21 OQR97998.1 - 0.24 11.2 1.0 23 4.9 0.0 2.9 2 0 0 2 2 2 0 TrkA-C domain Pkinase PF00069.25 OQR97999.1 - 5.1e-78 262.1 0.1 3.9e-77 259.2 0.1 2.0 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQR97999.1 - 8.6e-42 143.2 0.0 1.5e-41 142.4 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase EF-hand_1 PF00036.32 OQR97999.1 - 4e-19 66.7 5.7 9.8e-05 21.6 0.4 4.7 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.6 OQR97999.1 - 4.2e-17 60.5 3.1 0.0025 17.6 0.0 4.9 3 1 1 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 OQR97999.1 - 7.6e-17 60.9 6.2 9.5e-05 22.2 0.1 3.8 1 1 1 3 3 3 3 EF-hand domain pair EF-hand_7 PF13499.6 OQR97999.1 - 5.2e-16 58.8 2.1 9.2e-07 29.2 0.2 3.8 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.6 OQR97999.1 - 3.1e-09 35.9 0.2 0.2 11.2 0.0 4.4 4 0 0 4 4 4 3 EF hand EF-hand_4 PF12763.7 OQR97999.1 - 3.6e-06 26.9 0.8 0.21 11.5 0.1 3.5 3 0 0 3 3 3 2 Cytoskeletal-regulatory complex EF hand Kinase-like PF14531.6 OQR97999.1 - 7.3e-06 25.5 0.0 2e-05 24.1 0.0 1.6 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.14 OQR97999.1 - 0.00014 21.3 0.2 0.00024 20.5 0.2 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family EF-hand_9 PF14658.6 OQR97999.1 - 0.00031 21.0 1.3 0.0028 17.9 0.0 3.0 3 1 1 4 4 4 1 EF-hand domain Pkinase_fungal PF17667.1 OQR97999.1 - 0.0094 14.8 0.0 0.016 14.0 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 OQR97999.1 - 0.024 13.6 0.4 0.36 9.7 0.4 2.2 1 1 0 1 1 1 0 Haspin like kinase domain APH PF01636.23 OQR97999.1 - 0.038 13.9 0.1 0.18 11.7 0.1 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family SPARC_Ca_bdg PF10591.9 OQR97999.1 - 0.056 13.8 0.7 1.5 9.1 0.2 2.6 2 1 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region Pkinase_Tyr PF07714.17 OQR98000.1 - 6.5e-28 97.7 0.0 4.6e-25 88.4 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OQR98000.1 - 1.6e-26 93.3 0.0 6.4e-24 84.7 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain FAST_1 PF06743.15 OQR98001.1 - 0.0031 17.4 3.8 0.94 9.5 0.1 4.8 5 1 0 5 5 5 2 FAST kinase-like protein, subdomain 1 IBN_N PF03810.19 OQR98003.1 - 0.00054 19.8 1.9 1.1 9.2 0.1 3.1 2 1 1 3 3 3 2 Importin-beta N-terminal domain Arm PF00514.23 OQR98003.1 - 0.00079 19.4 4.3 5.7 7.1 0.3 3.9 4 0 0 4 4 4 3 Armadillo/beta-catenin-like repeat HEAT PF02985.22 OQR98003.1 - 0.096 13.0 1.6 4.2 7.9 0.0 3.7 4 1 0 4 4 4 0 HEAT repeat HEAT_EZ PF13513.6 OQR98003.1 - 0.13 12.8 2.0 23 5.6 0.0 3.1 2 1 2 4 4 4 0 HEAT-like repeat Mito_carr PF00153.27 OQR98054.1 - 3e-62 206.6 0.3 2.2e-22 78.8 0.1 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein Motile_Sperm PF00635.26 OQR98055.1 - 2.5e-26 91.7 0.1 4.5e-13 49.0 0.0 2.3 2 0 0 2 2 2 2 MSP (Major sperm protein) domain ASH PF15780.5 OQR98055.1 - 0.0022 18.2 0.3 2 8.6 0.1 2.5 2 0 0 2 2 2 2 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin Motile_Sperm PF00635.26 OQR98056.1 - 1.1e-32 112.1 0.1 9.2e-16 57.7 0.2 2.3 2 0 0 2 2 2 2 MSP (Major sperm protein) domain SpvD PF05563.12 OQR98056.1 - 0.094 12.3 0.0 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 Salmonella plasmid virulence protein SpvD FKBP_C PF00254.28 OQR98057.1 - 7e-19 68.0 0.0 1.5e-18 66.9 0.0 1.5 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase TPR_1 PF00515.28 OQR98057.1 - 2e-07 30.6 2.4 0.00035 20.3 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 OQR98057.1 - 2.6e-05 24.0 8.8 0.24 11.6 0.0 3.9 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_12 PF13424.6 OQR98057.1 - 0.0045 17.2 0.2 1.4 9.3 0.0 3.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.6 OQR98057.1 - 0.047 13.9 1.9 7.8 7.0 0.0 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.6 OQR98057.1 - 0.11 13.0 0.6 2.8 8.5 0.1 2.9 2 1 0 2 2 2 0 Tetratricopeptide repeat ADD_DNMT3 PF17980.1 OQR98057.1 - 0.62 10.1 2.9 0.62 10.1 0.5 2.3 1 1 1 2 2 2 0 Cysteine rich ADD domain in DNMT3 Myosin_head PF00063.21 OQR98058.1 - 3e-118 395.9 0.0 4e-118 395.5 0.0 1.2 1 0 0 1 1 1 1 Myosin head (motor domain) PDZ_6 PF17820.1 OQR98058.1 - 3.6e-14 52.3 0.3 0.00024 20.9 0.0 3.7 3 0 0 3 3 3 3 PDZ domain PDZ PF00595.24 OQR98058.1 - 1.7e-08 34.7 0.0 2.7e-05 24.5 0.0 3.1 3 0 0 3 3 3 2 PDZ domain IQ PF00612.27 OQR98058.1 - 3.9e-07 29.3 22.2 0.03 14.1 1.1 5.1 4 0 0 4 4 4 3 IQ calmodulin-binding motif PDZ_2 PF13180.6 OQR98058.1 - 6.1e-05 23.3 0.0 0.055 13.8 0.0 3.0 3 0 0 3 3 3 2 PDZ domain Pkinase PF00069.25 OQR98059.1 - 2e-13 50.3 0.4 2e-13 50.3 0.4 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQR98059.1 - 2.1e-10 40.3 0.2 2.2e-10 40.3 0.2 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OQR98059.1 - 0.026 13.8 0.0 0.026 13.8 0.0 1.0 1 0 0 1 1 1 0 Kinase-like Haspin_kinase PF12330.8 OQR98059.1 - 0.043 12.8 0.2 0.044 12.7 0.2 1.0 1 0 0 1 1 1 0 Haspin like kinase domain Pkinase_fungal PF17667.1 OQR98059.1 - 0.046 12.5 0.2 0.041 12.7 0.2 1.0 1 0 0 1 1 1 0 Fungal protein kinase APH PF01636.23 OQR98059.1 - 0.048 13.6 0.2 0.052 13.5 0.2 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.14 OQR98059.1 - 0.084 12.2 0.2 0.09 12.1 0.2 1.1 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PhoLip_ATPase_C PF16212.5 OQR98060.1 - 1.9e-69 234.2 20.7 1.9e-69 234.2 20.7 2.1 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal POT1 PF02765.17 OQR98060.1 - 7.3e-12 45.3 0.0 6.6e-11 42.2 0.0 2.4 2 0 0 2 2 2 1 Telomeric single stranded DNA binding POT1/CDC13 Hydrolase PF00702.26 OQR98060.1 - 3.7e-11 43.7 0.1 1.4e-06 28.7 0.0 2.9 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 OQR98060.1 - 3.8e-09 36.5 0.0 2.2e-08 34.1 0.0 2.2 2 0 0 2 2 2 1 Cation transport ATPase (P-type) E1-E2_ATPase PF00122.20 OQR98060.1 - 7.3e-05 22.4 0.9 0.00015 21.4 0.0 2.0 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase_3 PF08282.12 OQR98060.1 - 0.001 18.9 0.1 0.007 16.1 0.0 2.2 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 OQR98060.1 - 0.11 12.9 0.0 23 5.3 0.0 2.5 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase BT1 PF03092.16 OQR98061.1 - 1.3e-14 53.4 3.2 1.3e-14 53.4 3.2 2.6 3 0 0 3 3 3 2 BT1 family Yop-YscD_cpl PF16697.5 OQR98062.1 - 0.096 13.0 0.1 0.26 11.6 0.0 1.7 2 0 0 2 2 2 0 Inner membrane component of T3SS, cytoplasmic domain zf-Tim10_DDP PF02953.15 OQR98127.1 - 6.5e-19 67.3 4.0 8.4e-19 67.0 4.0 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger DUF842 PF05811.13 OQR98127.1 - 0.012 15.3 3.5 0.032 13.9 3.5 1.6 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF842) Ins_beta PF03488.14 OQR98127.1 - 0.055 13.5 0.5 0.089 12.8 0.5 1.3 1 0 0 1 1 1 0 Nematode insulin-related peptide beta type EF-hand_7 PF13499.6 OQR98128.1 - 5.6e-51 170.9 28.2 7.5e-11 42.3 0.3 9.0 8 0 0 8 8 8 7 EF-hand domain pair EF-hand_6 PF13405.6 OQR98128.1 - 1.4e-47 155.5 35.6 3.8e-05 23.3 0.0 14.6 15 0 0 15 15 14 10 EF-hand domain EF-hand_1 PF00036.32 OQR98128.1 - 2.7e-45 148.6 35.5 8.2e-05 21.9 0.0 14.2 15 0 0 15 15 15 9 EF hand EF-hand_5 PF13202.6 OQR98128.1 - 6.6e-27 91.8 29.2 0.00077 18.8 0.0 11.7 12 0 0 12 12 11 6 EF hand EF-hand_8 PF13833.6 OQR98128.1 - 7.4e-24 83.4 35.2 1.4e-08 34.5 0.3 11.3 10 3 3 13 13 13 6 EF-hand domain pair Dynein_light PF01221.18 OQR98128.1 - 3.8e-22 78.4 1.4 1.3e-21 76.7 1.4 1.9 1 0 0 1 1 1 1 Dynein light chain type 1 AA_kinase PF00696.28 OQR98128.1 - 4.2e-14 52.7 0.6 3.4e-13 49.8 0.5 2.4 2 0 0 2 2 2 1 Amino acid kinase family Peptidase_M14 PF00246.24 OQR98128.1 - 5.7e-12 46.0 0.0 1.3e-11 44.9 0.0 1.5 1 0 0 1 1 1 1 Zinc carboxypeptidase SPARC_Ca_bdg PF10591.9 OQR98128.1 - 2.1e-08 34.4 0.3 0.39 11.0 0.0 5.1 5 0 0 5 5 4 2 Secreted protein acidic and rich in cysteine Ca binding region Acetyltransf_1 PF00583.25 OQR98128.1 - 1.4e-07 31.8 0.0 3.2e-07 30.6 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family NnrU PF07298.11 OQR98128.1 - 2.3e-05 24.0 0.1 0.00021 20.8 0.1 2.2 1 1 0 1 1 1 1 NnrU protein Acetyltransf_7 PF13508.7 OQR98128.1 - 0.00018 21.9 0.0 0.00039 20.8 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 OQR98128.1 - 0.00061 19.7 0.0 0.0017 18.3 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Pepdidase_M14_N PF18027.1 OQR98128.1 - 0.0016 18.8 0.0 0.006 16.9 0.0 2.1 1 1 0 1 1 1 1 Cytosolic carboxypeptidase N-terminal domain EF-hand_4 PF12763.7 OQR98128.1 - 0.0035 17.3 8.5 19 5.3 0.1 5.7 4 2 1 5 5 5 0 Cytoskeletal-regulatory complex EF hand FAM91_C PF14648.6 OQR98128.1 - 0.026 13.4 0.1 5.8 5.6 0.0 2.7 3 0 0 3 3 3 0 FAM91 C-terminus AstE_AspA PF04952.14 OQR98128.1 - 0.044 12.8 0.0 0.089 11.9 0.0 1.4 1 0 0 1 1 1 0 Succinylglutamate desuccinylase / Aspartoacylase family EF-hand_9 PF14658.6 OQR98128.1 - 0.052 13.9 8.2 13 6.2 0.0 6.8 8 1 1 9 9 9 0 EF-hand domain SNURF PF07192.11 OQR98129.1 - 0.11 12.3 0.1 13 5.8 0.0 3.1 3 0 0 3 3 3 0 SNURF/RPN4 protein Ank_2 PF12796.7 OQR98130.1 - 1.3e-30 105.8 10.5 4.1e-08 33.7 0.4 7.2 6 1 1 7 7 7 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQR98130.1 - 1.9e-29 101.7 7.8 2.2e-07 31.3 0.4 8.8 7 1 0 7 7 7 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 OQR98130.1 - 1.2e-22 79.6 12.8 0.0011 19.2 0.1 10.5 4 3 6 10 10 10 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQR98130.1 - 1.4e-12 46.6 15.7 6.6 7.7 0.0 12.2 11 2 2 13 13 13 4 Ankyrin repeat Ank PF00023.30 OQR98130.1 - 0.071 13.6 13.4 27 5.4 0.0 7.8 7 4 1 8 8 8 0 Ankyrin repeat Prolamin_like PF05617.11 OQR98130.1 - 2.9 8.1 8.7 0.45 10.7 4.2 2.0 2 0 0 2 2 2 0 Prolamin-like RibD_C PF01872.17 OQR98229.1 - 1e-34 120.1 0.0 1.2e-34 119.9 0.0 1.0 1 0 0 1 1 1 1 RibD C-terminal domain AMP-binding PF00501.28 OQR98230.1 - 3.9e-75 253.1 0.0 5.1e-75 252.7 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme PP-binding PF00550.25 OQR98230.1 - 1e-07 32.2 0.0 2.2e-07 31.1 0.0 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site AMP-binding_C_2 PF14535.6 OQR98230.1 - 0.14 12.5 0.0 0.3 11.4 0.0 1.6 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain HIN PF02760.15 OQR98230.1 - 0.15 11.8 0.0 1.5 8.5 0.0 2.3 2 0 0 2 2 2 0 HIN-200/IF120x domain Seipin PF06775.14 OQR98231.1 - 2.7e-36 125.5 2.5 4.5e-36 124.8 2.5 1.3 1 0 0 1 1 1 1 Putative adipose-regulatory protein (Seipin) LicD PF04991.13 OQR98232.1 - 3.6e-21 76.3 0.3 5.3e-20 72.5 0.3 2.4 1 1 0 1 1 1 1 LicD family Nucleoside_tran PF01733.18 OQR98233.1 - 5.3e-17 62.2 7.1 3.5e-15 56.2 7.1 2.1 1 1 0 1 1 1 1 Nucleoside transporter PUCC PF03209.15 OQR98233.1 - 0.07 12.1 0.2 0.07 12.1 0.2 2.1 2 0 0 2 2 2 0 PUCC protein SH3_1 PF00018.28 OQR98234.1 - 3.6e-14 52.1 0.1 9.1e-14 50.8 0.1 1.8 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 OQR98234.1 - 4.8e-13 48.8 0.2 1.2e-12 47.5 0.2 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 OQR98234.1 - 1e-12 47.5 0.2 4.6e-12 45.4 0.2 2.2 2 0 0 2 2 2 1 Variant SH3 domain HELP PF03451.14 OQR98234.1 - 3e-10 39.8 0.0 1.7e-09 37.4 0.1 2.2 2 0 0 2 2 2 1 HELP motif WD40 PF00400.32 OQR98234.1 - 4.5e-10 39.9 21.2 0.022 15.6 0.0 8.8 9 0 0 9 9 9 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OQR98234.1 - 2.5e-08 34.1 0.1 0.013 15.8 0.0 4.2 3 1 0 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 OQR98234.1 - 0.003 16.9 0.0 0.028 13.8 0.1 2.3 2 0 0 2 2 2 1 WD40-like domain Calycin_like PF13944.6 OQR98234.1 - 0.019 15.2 0.1 0.045 14.1 0.1 1.6 1 0 0 1 1 1 0 Calycin-like beta-barrel domain zf-RanBP PF00641.18 OQR98235.1 - 2e-08 33.4 24.5 3.2e-05 23.2 8.6 2.4 2 0 0 2 2 2 2 Zn-finger in Ran binding protein and others DZR PF12773.7 OQR98235.1 - 0.24 11.5 14.9 0.49 10.5 14.9 1.6 1 0 0 1 1 1 0 Double zinc ribbon Crystall PF00030.19 OQR98236.1 - 8e-08 32.4 0.3 1.4e-07 31.6 0.3 1.4 1 0 0 1 1 1 1 Beta/Gamma crystallin Inhibitor_I36 PF03995.13 OQR98236.1 - 0.00023 21.0 1.9 0.0029 17.5 0.2 2.2 1 1 1 2 2 2 1 Peptidase inhibitor family I36 Crystall_3 PF08964.10 OQR98236.1 - 0.037 14.2 0.3 6.2 7.1 0.1 2.2 1 1 0 2 2 2 0 Beta/Gamma crystallin FPL PF09758.9 OQR98237.1 - 8.8e-47 158.8 9.3 1.9e-46 157.7 9.3 1.6 1 0 0 1 1 1 1 Uncharacterised conserved protein FAM176 PF14851.6 OQR98237.1 - 0.12 12.0 1.3 0.57 9.8 0.0 2.3 2 0 0 2 2 2 0 FAM176 family DUF4677 PF15726.5 OQR98237.1 - 0.9 9.7 3.7 19 5.4 0.4 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4677) DUF4611 PF15387.6 OQR98237.1 - 2.1 8.6 9.1 0.25 11.6 2.3 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) GlcNAc PF11397.8 OQR98238.1 - 1.1e-42 146.7 0.0 2.8e-35 122.4 0.0 2.2 1 1 1 2 2 2 2 Glycosyltransferase (GlcNAc) Glycos_transf_2 PF00535.26 OQR98238.1 - 0.00011 22.0 0.0 0.00022 21.1 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferase family 2 Beta-lactamase PF00144.24 OQR98239.1 - 2.1e-20 73.3 0.2 5.1e-16 58.8 0.2 2.5 1 1 0 1 1 1 1 Beta-lactamase Crystall PF00030.19 OQR98240.1 - 4e-06 27.0 0.4 7.9e-06 26.0 0.4 1.5 1 1 0 1 1 1 1 Beta/Gamma crystallin Inhibitor_I36 PF03995.13 OQR98240.1 - 1.3e-05 25.0 3.0 0.0035 17.2 0.3 2.4 1 1 1 2 2 2 2 Peptidase inhibitor family I36 Crystall_3 PF08964.10 OQR98240.1 - 0.00023 21.2 0.5 0.023 14.8 0.2 2.2 1 1 1 2 2 2 2 Beta/Gamma crystallin Rad1 PF02144.16 OQR98241.1 - 4.5e-29 101.4 3.8 8.8e-29 100.4 2.9 1.8 2 0 0 2 2 2 1 Repair protein Rad1/Rec1/Rad17 TPR_12 PF13424.6 OQR98241.1 - 8.9e-24 83.6 13.3 5.4e-08 33.0 4.6 5.5 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_10 PF13374.6 OQR98241.1 - 2.8e-10 39.7 1.9 0.058 13.3 0.3 6.9 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_7 PF13176.6 OQR98241.1 - 6.9e-05 22.6 5.1 0.91 9.7 0.0 5.0 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_1 PF00515.28 OQR98241.1 - 0.019 14.7 20.7 0.061 13.2 0.6 6.9 7 0 0 7 7 7 0 Tetratricopeptide repeat C1_2 PF03107.16 OQR98241.1 - 0.22 11.9 4.2 0.84 10.0 4.2 2.0 1 0 0 1 1 1 0 C1 domain TPR_8 PF13181.6 OQR98241.1 - 0.67 10.3 22.7 0.97 9.8 0.4 7.0 8 0 0 8 8 8 0 Tetratricopeptide repeat ANAPC5 PF12862.7 OQR98241.1 - 0.71 10.0 8.4 8.6 6.5 0.2 4.7 5 0 0 5 5 5 0 Anaphase-promoting complex subunit 5 TPR_6 PF13174.6 OQR98241.1 - 0.82 10.4 7.5 4.1 8.2 0.3 4.8 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_2 PF07719.17 OQR98241.1 - 0.91 9.8 28.8 0.92 9.8 1.0 7.3 8 0 0 8 8 8 0 Tetratricopeptide repeat Ras PF00071.22 OQR98242.1 - 4.3e-59 198.7 0.3 5.8e-59 198.3 0.3 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OQR98242.1 - 1.2e-34 119.1 0.3 1.8e-34 118.5 0.3 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OQR98242.1 - 1.1e-16 60.8 0.1 1.4e-16 60.4 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 OQR98242.1 - 6.6e-07 28.9 0.0 9e-07 28.5 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 OQR98242.1 - 1.7e-06 28.1 0.1 2.8e-06 27.4 0.1 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 OQR98242.1 - 2.1e-06 27.4 0.3 1.8e-05 24.4 0.3 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 OQR98242.1 - 9.5e-06 25.6 0.8 0.0082 16.1 0.1 2.2 2 0 0 2 2 2 2 RsgA GTPase AAA_22 PF13401.6 OQR98242.1 - 0.0014 18.9 0.3 0.0065 16.7 0.1 2.1 2 1 0 2 2 1 1 AAA domain PduV-EutP PF10662.9 OQR98242.1 - 0.0021 17.8 0.1 0.0075 16.0 0.0 2.0 1 1 1 2 2 2 1 Ethanolamine utilisation - propanediol utilisation AAA_16 PF13191.6 OQR98242.1 - 0.0027 18.1 0.1 0.005 17.2 0.1 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_7 PF12775.7 OQR98242.1 - 0.0033 17.0 0.1 0.0061 16.1 0.1 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region SRPRB PF09439.10 OQR98242.1 - 0.004 16.6 0.0 0.0062 16.0 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit NTPase_1 PF03266.15 OQR98242.1 - 0.0074 16.2 0.0 0.012 15.5 0.0 1.4 1 0 0 1 1 1 1 NTPase TniB PF05621.11 OQR98242.1 - 0.0079 15.6 0.0 0.014 14.9 0.0 1.4 1 0 0 1 1 1 1 Bacterial TniB protein AAA_33 PF13671.6 OQR98242.1 - 0.0082 16.3 0.7 0.015 15.5 0.2 1.6 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.14 OQR98242.1 - 0.014 15.4 0.0 0.027 14.5 0.0 1.6 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) ATP_bind_1 PF03029.17 OQR98242.1 - 0.015 15.1 0.0 0.24 11.1 0.0 2.0 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein ABC_tran PF00005.27 OQR98242.1 - 0.024 15.1 0.0 0.043 14.3 0.0 1.5 1 0 0 1 1 1 0 ABC transporter AAA_24 PF13479.6 OQR98242.1 - 0.05 13.3 0.0 0.075 12.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain DNA_pol_E_B PF04042.16 OQR98242.1 - 0.06 12.7 0.0 0.12 11.7 0.0 1.4 1 0 0 1 1 1 0 DNA polymerase alpha/epsilon subunit B AAA_29 PF13555.6 OQR98242.1 - 0.082 12.7 0.3 0.31 10.8 0.3 2.0 1 1 0 1 1 1 0 P-loop containing region of AAA domain MCM PF00493.23 OQR98242.1 - 0.091 11.8 0.0 0.15 11.1 0.0 1.3 1 0 0 1 1 1 0 MCM P-loop domain ATPase_2 PF01637.18 OQR98242.1 - 0.13 12.2 0.1 0.21 11.5 0.1 1.2 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea FeoB_N PF02421.18 OQR98242.1 - 0.15 11.6 0.5 0.5 9.9 0.2 2.1 2 1 0 2 2 2 0 Ferrous iron transport protein B NACHT PF05729.12 OQR98242.1 - 0.16 11.9 0.0 0.29 11.0 0.0 1.4 1 0 0 1 1 1 0 NACHT domain Crystall PF00030.19 OQR98243.1 - 0.00014 22.0 0.1 0.00035 20.7 0.1 1.8 1 0 0 1 1 1 1 Beta/Gamma crystallin Crystall_3 PF08964.10 OQR98243.1 - 0.023 14.9 0.3 3 8.1 0.1 2.5 1 1 1 2 2 2 0 Beta/Gamma crystallin Anoctamin PF04547.12 OQR98244.1 - 3.5e-26 92.1 2.7 3.7e-26 92.0 2.7 1.0 1 0 0 1 1 1 1 Calcium-activated chloride channel Borrelia_REV PF03978.13 OQR98244.1 - 0.14 12.1 0.0 0.22 11.5 0.0 1.3 1 0 0 1 1 1 0 Borrelia burgdorferi REV protein tRNA-synt_1 PF00133.22 OQR98245.1 - 8.2e-201 668.4 0.0 8.4e-200 665.0 0.0 2.0 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 OQR98245.1 - 5.2e-41 140.1 0.0 1.1e-40 139.1 0.0 1.5 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 OQR98245.1 - 2.4e-14 52.9 1.1 2.6e-06 26.4 0.3 4.7 4 1 0 4 4 4 3 tRNA synthetases class I (M) Myb_DNA-binding PF00249.31 OQR98245.1 - 2.5e-13 50.0 0.3 5.6e-13 48.9 0.3 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain tRNA-synt_1_2 PF13603.6 OQR98245.1 - 1.1e-12 47.8 0.0 3.8e-09 36.3 0.0 2.6 1 1 1 2 2 2 2 Leucyl-tRNA synthetase, Domain 2 Val_tRNA-synt_C PF10458.9 OQR98245.1 - 2.2e-08 34.2 1.1 7.4e-08 32.6 1.1 1.9 1 0 0 1 1 1 1 Valyl tRNA synthetase tRNA binding arm Myb_DNA-bind_6 PF13921.6 OQR98245.1 - 0.00016 21.8 0.3 0.00044 20.4 0.3 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OQR98245.1 - 0.014 15.3 0.1 0.039 13.9 0.1 1.7 1 0 0 1 1 1 0 Myb DNA-binding like tRNA-synt_1e PF01406.19 OQR98245.1 - 0.023 14.0 0.0 4.5 6.5 0.0 2.8 3 0 0 3 3 3 0 tRNA synthetases class I (C) catalytic domain SHIPPO-rpt PF07004.12 OQR98288.1 - 1.5e-18 66.7 22.0 0.0011 19.7 0.6 6.6 6 0 0 6 6 6 6 Sperm-tail PG-rich repeat Cornifin PF02389.15 OQR98288.1 - 0.48 10.6 6.8 0.27 11.4 3.1 2.3 1 1 0 2 2 2 0 Cornifin (SPRR) family Mce4_CUP1 PF11887.8 OQR98289.1 - 0.69 9.3 5.3 1.1 8.7 0.1 2.7 3 0 0 3 3 3 0 Cholesterol uptake porter CUP1 of Mce4, putative IPP-2 PF04979.14 OQR98290.1 - 4.2e-20 72.9 13.3 6.1e-20 72.3 13.3 1.2 1 0 0 1 1 1 1 Protein phosphatase inhibitor 2 (IPP-2) Tubulin PF00091.25 OQR98291.1 - 8.5e-45 153.4 0.3 1.4e-44 152.7 0.3 1.4 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_2 PF13809.6 OQR98291.1 - 0.06 12.5 0.9 0.21 10.7 0.7 1.9 1 1 1 2 2 2 0 Tubulin like SATase_N PF06426.14 OQR98291.1 - 0.089 13.2 0.1 6.4 7.2 0.0 3.5 4 0 0 4 4 4 0 Serine acetyltransferase, N-terminal START PF01852.19 OQR98292.1 - 2.9e-06 26.9 0.1 8.9e-06 25.2 0.0 1.8 1 1 1 2 2 2 1 START domain zf-C4H2 PF10146.9 OQR98292.1 - 0.067 13.5 0.5 0.11 12.7 0.5 1.3 1 0 0 1 1 1 0 Zinc finger-containing protein ADH_zinc_N PF00107.26 OQR98293.1 - 1e-25 90.2 0.3 1.5e-25 89.6 0.3 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 OQR98293.1 - 1.4e-24 87.6 0.0 3.2e-24 86.5 0.0 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 OQR98293.1 - 3.1e-10 39.9 0.1 9e-09 35.2 0.0 2.4 2 1 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain adh_short PF00106.25 OQR98293.1 - 0.038 13.5 0.4 0.075 12.5 0.4 1.5 1 0 0 1 1 1 0 short chain dehydrogenase EIIA-man PF03610.16 OQR98293.1 - 0.087 13.1 0.1 0.19 12.0 0.1 1.5 1 0 0 1 1 1 0 PTS system fructose IIA component Lpp-LpqN PF10738.9 OQR98293.1 - 0.14 11.6 0.0 0.28 10.6 0.0 1.4 1 0 0 1 1 1 0 Probable lipoprotein LpqN START PF01852.19 OQR98294.1 - 0.00022 20.7 0.0 0.00044 19.7 0.0 1.4 1 0 0 1 1 1 1 START domain FYVE PF01363.21 OQR98294.1 - 0.00082 19.5 9.8 0.0025 17.9 9.8 1.9 1 0 0 1 1 1 1 FYVE zinc finger DUF1624 PF07786.12 OQR98295.1 - 0.00052 19.6 4.6 0.0015 18.2 4.6 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF1624) DUF5009 PF16401.5 OQR98295.1 - 0.00087 18.9 2.5 0.0022 17.5 1.2 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF5009) AA_permease_2 PF13520.6 OQR98296.1 - 2.1e-37 129.0 47.5 2.7e-37 128.6 47.5 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 OQR98296.1 - 4e-22 78.5 37.3 5.7e-22 78.0 37.3 1.1 1 0 0 1 1 1 1 Amino acid permease HSP70 PF00012.20 OQR98297.1 - 1e-116 390.5 1.3 1.2e-116 390.3 1.3 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 OQR98297.1 - 1.2e-12 47.3 0.1 1.7e-12 46.8 0.1 1.2 1 0 0 1 1 1 1 MreB/Mbl protein Hydantoinase_A PF01968.18 OQR98297.1 - 0.04 13.2 0.0 0.066 12.5 0.0 1.3 1 0 0 1 1 1 0 Hydantoinase/oxoprolinase Actin PF00022.19 OQR98297.1 - 0.076 11.6 0.1 4.3 5.8 0.0 2.1 1 1 1 2 2 2 0 Actin TPP_enzyme_N PF02776.18 OQR98297.1 - 0.11 12.1 0.1 0.21 11.2 0.1 1.4 1 0 0 1 1 1 0 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain SAD_SRA PF02182.17 OQR98336.1 - 0.0031 17.2 0.1 0.0052 16.5 0.1 1.3 1 0 0 1 1 1 1 SAD/SRA domain Cwf_Cwc_15 PF04889.12 OQR98336.1 - 0.16 11.7 1.0 0.26 11.0 1.0 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein PPR_2 PF13041.6 OQR98337.1 - 3.9e-20 71.8 3.5 5e-06 26.6 0.0 5.6 5 1 1 6 6 6 3 PPR repeat family PPR PF01535.20 OQR98337.1 - 4.2e-15 54.9 0.3 0.03 14.6 0.0 7.7 8 0 0 8 8 8 3 PPR repeat PPR_3 PF13812.6 OQR98337.1 - 1.7e-09 37.6 0.0 1.5e-05 25.0 0.0 3.6 4 0 0 4 4 4 2 Pentatricopeptide repeat domain PPR_long PF17177.4 OQR98337.1 - 1.2e-06 28.0 0.7 0.34 10.3 0.0 3.8 2 1 1 4 4 4 2 Pentacotripeptide-repeat region of PRORP ANAPC3 PF12895.7 OQR98337.1 - 0.00048 20.3 0.4 0.64 10.3 0.0 3.0 2 0 0 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.6 OQR98337.1 - 0.0029 18.1 1.6 0.42 11.2 0.0 3.5 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 OQR98337.1 - 0.0034 18.1 0.5 0.77 10.7 0.0 4.4 3 2 1 5 5 4 1 Tetratricopeptide repeat TPR_12 PF13424.6 OQR98337.1 - 0.015 15.6 3.2 0.86 9.9 0.2 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_3 PF07720.12 OQR98337.1 - 0.043 13.8 4.2 0.15 12.1 0.6 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.6 OQR98337.1 - 0.065 13.9 0.0 19 6.0 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.28 OQR98337.1 - 0.42 10.5 5.4 22 5.1 0.0 4.9 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_2 PF07719.17 OQR98337.1 - 0.51 10.6 4.3 74 3.8 0.0 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat Rgp1 PF08737.10 OQR98339.1 - 1.4e-14 54.1 0.2 6.9e-10 38.7 0.0 2.2 1 1 1 2 2 2 2 Rgp1 Arrestin_C PF02752.22 OQR98339.1 - 0.003 18.0 0.0 0.062 13.7 0.0 2.9 2 2 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain T4-gp15_tss PF16724.5 OQR98339.1 - 0.13 12.0 0.0 0.18 11.5 0.0 1.2 1 0 0 1 1 1 0 T4-like virus Myoviridae tail sheath stabiliser Arrestin_N PF00339.29 OQR98339.1 - 0.22 11.6 0.5 9 6.4 0.1 2.3 2 0 0 2 2 2 0 Arrestin (or S-antigen), N-terminal domain NUC153 PF08159.12 OQR98341.1 - 2.5e-11 43.2 6.2 3.2e-07 30.0 0.5 3.8 3 0 0 3 3 3 3 NUC153 domain DUF573 PF04504.14 OQR98341.1 - 0.039 14.6 0.3 0.039 14.6 0.3 4.9 4 2 1 5 5 5 0 Protein of unknown function, DUF573 Ribosomal_L23 PF00276.20 OQR98342.1 - 1.5e-19 70.2 4.0 1.7e-19 70.0 4.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L23 Cys_rich_VLP PF14194.6 OQR98343.1 - 0.049 13.8 0.8 0.1 12.7 0.8 1.5 1 0 0 1 1 1 0 Cysteine-rich VLP Cyclin_N PF00134.23 OQR98344.1 - 3.1e-25 88.4 0.8 5.6e-25 87.5 0.8 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 OQR98344.1 - 5e-08 33.0 2.2 8.8e-08 32.2 1.5 1.8 2 0 0 2 2 2 1 Cyclin, C-terminal domain NiFe_hyd_SSU_C PF14720.6 OQR98344.1 - 0.0091 16.3 1.5 0.98 9.8 0.1 2.6 2 0 0 2 2 2 2 NiFe/NiFeSe hydrogenase small subunit C-terminal Ribosomal_L7Ae PF01248.26 OQR98345.1 - 2.2e-23 81.8 2.1 2.9e-23 81.4 0.8 1.7 2 0 0 2 2 2 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family PTSIIB_sorb PF03830.15 OQR98345.1 - 0.031 14.5 0.3 0.041 14.1 0.3 1.2 1 0 0 1 1 1 0 PTS system sorbose subfamily IIB component Mlf1IP PF10248.9 OQR98345.1 - 0.11 12.5 0.0 0.16 11.9 0.0 1.2 1 0 0 1 1 1 0 Myelodysplasia-myeloid leukemia factor 1-interacting protein Nup54 PF13874.6 OQR98346.1 - 2.4e-37 128.2 1.8 4.2e-37 127.4 1.8 1.4 1 0 0 1 1 1 1 Nucleoporin complex subunit 54 GFP PF01353.22 OQR98346.1 - 0.055 12.9 0.0 0.094 12.2 0.0 1.3 1 0 0 1 1 1 0 Green fluorescent protein ZapB PF06005.12 OQR98346.1 - 0.54 10.7 2.7 16 6.0 0.4 2.7 2 0 0 2 2 2 0 Cell division protein ZapB Ribosomal_S28e PF01200.18 OQR98347.1 - 1.2e-31 108.4 0.5 1.4e-31 108.3 0.5 1.0 1 0 0 1 1 1 1 Ribosomal protein S28e Choline_kinase PF01633.20 OQR98358.1 - 1.1e-46 159.2 0.1 1.8e-46 158.4 0.1 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.23 OQR98358.1 - 8.8e-07 29.1 0.0 1.7e-06 28.1 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase PF00069.25 OQR98358.1 - 0.029 13.7 0.1 0.058 12.7 0.0 1.5 1 1 0 1 1 1 0 Protein kinase domain DUF1679 PF07914.11 OQR98358.1 - 0.05 12.5 0.1 0.066 12.1 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) EcKinase PF02958.20 OQR98358.1 - 0.053 12.8 0.2 0.13 11.6 0.2 1.6 1 1 0 1 1 1 0 Ecdysteroid kinase Filo_VP35 PF02097.15 OQR98358.1 - 0.088 11.9 0.0 0.12 11.4 0.0 1.2 1 0 0 1 1 1 0 Filoviridae VP35 JTB PF05439.12 OQR98359.1 - 4.2e-05 23.6 0.0 5.1e-05 23.3 0.0 1.1 1 0 0 1 1 1 1 Jumping translocation breakpoint protein (JTB) Glyco_transf_20 PF00982.21 OQR98360.1 - 3.9e-111 372.0 0.0 5.2e-111 371.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.16 OQR98360.1 - 4.7e-15 55.4 0.0 2.4e-14 53.0 0.0 1.9 2 0 0 2 2 2 1 Trehalose-phosphatase CBM_20 PF00686.19 OQR98360.1 - 3.3e-06 26.9 0.0 0.036 14.0 0.0 2.5 2 0 0 2 2 2 2 Starch binding domain OMP_b-brl PF13505.6 OQR98361.1 - 0.23 11.6 2.8 0.39 10.8 2.8 1.3 1 0 0 1 1 1 0 Outer membrane protein beta-barrel domain PKcGMP_CC PF16808.5 OQR98362.1 - 6.7e-05 22.7 1.9 0.23 11.3 0.0 3.0 2 0 0 2 2 2 2 Coiled-coil N-terminus of cGMP-dependent protein kinase ABC_tran_CTD PF16326.5 OQR98362.1 - 0.00018 21.7 18.5 0.38 11.0 0.7 4.3 4 0 0 4 4 4 2 ABC transporter C-terminal domain GAS PF13851.6 OQR98362.1 - 0.003 16.9 24.8 0.011 15.1 7.2 2.3 1 1 0 2 2 2 2 Growth-arrest specific micro-tubule binding DUF641 PF04859.12 OQR98362.1 - 0.005 17.2 16.1 0.038 14.3 2.9 3.1 2 1 1 3 3 3 2 Plant protein of unknown function (DUF641) COG5 PF10392.9 OQR98362.1 - 0.0093 16.1 16.6 0.13 12.5 2.1 3.4 1 1 1 3 3 3 2 Golgi transport complex subunit 5 HOOK PF05622.12 OQR98362.1 - 0.01 14.0 23.6 0.073 11.2 8.1 2.4 1 1 1 2 2 2 0 HOOK protein ADIP PF11559.8 OQR98362.1 - 0.013 15.6 5.0 0.013 15.6 5.0 4.2 1 1 2 4 4 4 0 Afadin- and alpha -actinin-Binding Fez1 PF06818.15 OQR98362.1 - 0.02 15.4 23.4 0.021 15.3 8.0 2.1 1 1 1 2 2 2 0 Fez1 UPF0242 PF06785.11 OQR98362.1 - 0.02 15.0 24.3 0.16 12.1 19.1 2.9 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus ATG16 PF08614.11 OQR98362.1 - 0.023 15.0 25.3 0.68 10.1 25.3 2.3 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) ZapB PF06005.12 OQR98362.1 - 0.029 14.8 24.4 0.81 10.2 4.2 4.4 1 1 2 3 3 3 0 Cell division protein ZapB SPT16 PF08644.11 OQR98362.1 - 0.032 14.4 1.2 0.032 14.4 1.2 2.5 1 1 0 2 2 2 0 FACT complex subunit (SPT16/CDC68) Hrs_helical PF12210.8 OQR98362.1 - 0.041 14.4 17.9 0.21 12.1 1.2 3.8 2 1 2 4 4 4 0 Hepatocyte growth factor-regulated tyrosine kinase substrate DUF4140 PF13600.6 OQR98362.1 - 0.045 14.2 17.0 0.73 10.3 0.5 3.9 2 1 1 3 3 2 0 N-terminal domain of unknown function (DUF4140) KptA_kDCL PF18176.1 OQR98362.1 - 0.054 13.4 0.7 0.081 12.8 0.7 1.4 1 0 0 1 1 1 0 KptA in kinetoplastid DICER domain End3 PF12761.7 OQR98362.1 - 0.065 13.4 0.3 0.065 13.4 0.3 3.0 2 1 1 3 3 3 0 Actin cytoskeleton-regulatory complex protein END3 DUF4988 PF16378.5 OQR98362.1 - 0.081 12.6 6.0 0.14 11.8 0.2 2.8 3 0 0 3 3 2 0 Domain of unknown function MerR-DNA-bind PF09278.11 OQR98362.1 - 0.11 13.0 8.1 1.1 9.9 0.0 3.7 3 1 1 4 4 4 0 MerR, DNA binding TSC22 PF01166.18 OQR98362.1 - 0.26 11.6 9.6 11 6.4 0.6 4.3 3 2 1 4 4 4 0 TSC-22/dip/bun family DUF724 PF05266.14 OQR98362.1 - 0.64 9.8 19.8 1.5 8.6 1.1 3.4 1 1 2 4 4 4 0 Protein of unknown function (DUF724) DUF4618 PF15397.6 OQR98362.1 - 0.65 9.4 24.3 0.14 11.5 0.4 3.4 1 1 2 3 3 3 0 Domain of unknown function (DUF4618) DUF1796 PF08795.10 OQR98362.1 - 0.99 9.3 5.0 1 9.3 1.0 2.2 1 1 1 2 2 2 0 Putative papain-like cysteine peptidase (DUF1796) YabA PF06156.13 OQR98362.1 - 1 10.1 22.5 3.3 8.4 2.6 4.0 1 1 3 4 4 4 0 Initiation control protein YabA DASH_Dam1 PF08653.10 OQR98362.1 - 1.4 8.8 8.7 41 4.1 0.1 4.4 4 2 0 4 4 4 0 DASH complex subunit Dam1 DUF1664 PF07889.12 OQR98362.1 - 1.6 8.8 14.4 0.67 10.0 1.4 3.6 1 1 2 4 4 4 0 Protein of unknown function (DUF1664) HALZ PF02183.18 OQR98362.1 - 1.6 9.0 11.8 1.4 9.2 0.3 4.7 5 0 0 5 5 4 0 Homeobox associated leucine zipper CENP-H PF05837.12 OQR98362.1 - 1.7 9.1 25.2 0.95 9.9 7.7 3.1 1 1 0 2 2 2 0 Centromere protein H (CENP-H) Fib_alpha PF08702.10 OQR98362.1 - 2 8.6 20.4 0.38 10.9 2.5 2.8 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family CREPT PF16566.5 OQR98362.1 - 2 8.6 23.1 8.3 6.6 5.3 3.3 1 1 2 3 3 3 0 Cell-cycle alteration and expression-elevated protein in tumour Sec34 PF04136.15 OQR98362.1 - 2.3 8.1 21.4 1.4 8.8 4.3 3.3 2 2 1 3 3 3 0 Sec34-like family APG6_N PF17675.1 OQR98362.1 - 2.7 8.5 30.1 0.084 13.4 6.5 3.3 1 1 1 2 2 1 0 Apg6 coiled-coil region TMF_DNA_bd PF12329.8 OQR98362.1 - 3.5 7.7 23.1 0.3 11.1 3.7 3.8 3 1 0 3 3 3 0 TATA element modulatory factor 1 DNA binding HIP1_clath_bdg PF16515.5 OQR98362.1 - 3.5 8.3 23.9 6.5 7.4 7.6 4.0 1 1 2 4 4 4 0 Clathrin-binding domain of Huntingtin-interacting protein 1 OmpH PF03938.14 OQR98362.1 - 3.6 7.9 19.1 0.91 9.9 0.9 3.4 1 1 2 3 3 3 0 Outer membrane protein (OmpH-like) DUF16 PF01519.16 OQR98362.1 - 4 8.0 15.3 13 6.3 1.1 3.2 1 1 2 3 3 2 0 Protein of unknown function DUF16 CENP-F_leu_zip PF10473.9 OQR98362.1 - 4.7 7.2 28.0 3 7.8 4.7 4.0 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 CLZ PF16526.5 OQR98362.1 - 5.6 7.4 21.5 2.1 8.7 0.3 5.0 3 1 2 5 5 5 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Prefoldin_2 PF01920.20 OQR98362.1 - 7.9 6.5 21.9 1.3 9.0 1.2 4.5 1 1 2 4 4 4 0 Prefoldin subunit DivIC PF04977.15 OQR98362.1 - 9 6.2 17.9 8.3 6.3 0.2 4.6 2 2 3 5 5 5 0 Septum formation initiator E1-E2_ATPase PF00122.20 OQR98363.1 - 7.7e-53 178.7 0.8 7.7e-53 178.7 0.8 2.6 3 0 0 3 3 3 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 OQR98363.1 - 2.3e-49 167.6 3.2 2.3e-49 167.6 3.2 1.7 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 OQR98363.1 - 4.4e-20 72.9 0.6 3.8e-18 66.5 0.6 2.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 OQR98363.1 - 9.8e-19 66.8 0.2 4.1e-18 64.8 0.1 2.2 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 OQR98363.1 - 7.9e-18 64.3 0.0 1.9e-17 63.1 0.0 1.7 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 OQR98363.1 - 9.7e-05 22.2 1.7 9.7e-05 22.2 1.7 1.7 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 OQR98363.1 - 0.13 12.7 0.0 0.58 10.5 0.0 2.2 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase FWWh PF14922.6 OQR98364.1 - 2.2e-16 60.1 0.5 3.9e-16 59.3 0.5 1.4 1 0 0 1 1 1 1 Protein of unknown function DUF4606 PF15379.6 OQR98364.1 - 0.032 14.5 0.6 0.13 12.5 0.6 2.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4606) DUF4956 PF16316.5 OQR98364.1 - 0.052 13.2 0.1 0.093 12.4 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4956) tRNA-synt_1c PF00749.21 OQR98366.1 - 3.2e-105 351.5 0.0 4e-105 351.2 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain DUF4037 PF13228.6 OQR98366.1 - 0.14 13.0 0.1 0.36 11.7 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4037) CDP-OH_P_transf PF01066.21 OQR98382.1 - 3.8e-14 53.2 0.3 3.8e-14 53.2 0.3 3.6 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase Fun_ATP-synt_8 PF05933.13 OQR98382.1 - 5.7 7.2 10.0 0.29 11.3 2.5 2.8 3 0 0 3 3 3 0 Fungal ATP synthase protein 8 (A6L) WD40 PF00400.32 OQR98384.1 - 1.9e-08 34.8 1.0 4.8e-05 24.0 0.0 4.8 6 0 0 6 6 6 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OQR98384.1 - 0.0029 17.9 0.0 3.1 8.2 0.0 3.1 1 1 3 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain C1_2 PF03107.16 OQR98384.1 - 0.17 12.2 0.5 0.54 10.6 0.5 1.8 1 0 0 1 1 1 0 C1 domain Kelch_1 PF01344.25 OQR98384.1 - 0.26 10.9 1.9 7.2 6.3 0.1 3.4 4 0 0 4 4 4 0 Kelch motif NPV_P10 PF05531.12 OQR98385.1 - 0.0012 19.2 0.3 0.0012 19.2 0.3 4.3 3 1 1 4 4 4 1 Nucleopolyhedrovirus P10 protein Spc7 PF08317.11 OQR98385.1 - 0.0016 17.4 12.6 0.0016 17.4 12.6 2.7 2 1 1 3 3 3 1 Spc7 kinetochore protein Fib_alpha PF08702.10 OQR98385.1 - 0.0059 16.8 6.4 0.0059 16.8 6.4 3.0 2 1 1 3 3 3 1 Fibrinogen alpha/beta chain family KxDL PF10241.9 OQR98385.1 - 0.016 15.5 3.0 0.016 15.5 3.0 4.0 3 1 1 4 4 4 0 Uncharacterized conserved protein DUF4315 PF14193.6 OQR98385.1 - 0.044 13.8 5.8 3.7 7.6 0.1 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4315) ZapB PF06005.12 OQR98385.1 - 0.052 14.0 2.6 0.052 14.0 2.6 4.3 3 2 0 3 3 2 0 Cell division protein ZapB FapA PF03961.13 OQR98385.1 - 0.18 10.4 12.0 0.33 9.5 6.7 2.2 1 1 0 2 2 2 0 Flagellar Assembly Protein A DUF4164 PF13747.6 OQR98385.1 - 0.24 11.7 22.5 0.41 11.0 2.3 4.3 4 0 0 4 4 4 0 Domain of unknown function (DUF4164) DUF1957 PF09210.11 OQR98385.1 - 0.32 11.4 6.8 0.26 11.7 0.4 3.1 1 1 1 3 3 3 0 Domain of unknown function (DUF1957) ATG16 PF08614.11 OQR98385.1 - 0.6 10.3 36.0 0.29 11.4 16.4 3.3 2 1 1 3 3 3 0 Autophagy protein 16 (ATG16) DUF5082 PF16888.5 OQR98385.1 - 0.67 10.2 20.6 0.093 13.0 1.6 3.5 4 0 0 4 4 4 0 Domain of unknown function (DUF5082) Prefoldin_2 PF01920.20 OQR98385.1 - 1.5 8.8 22.3 1 9.3 0.3 3.3 3 1 0 3 3 3 0 Prefoldin subunit UPF0242 PF06785.11 OQR98385.1 - 3.3 7.8 37.0 0.16 12.0 16.4 3.0 2 1 1 3 3 3 0 Uncharacterised protein family (UPF0242) N-terminus BRE1 PF08647.11 OQR98385.1 - 3.6 7.7 21.0 4.4 7.4 9.7 3.8 2 1 2 4 4 4 0 BRE1 E3 ubiquitin ligase DUF948 PF06103.11 OQR98385.1 - 5.2 7.4 7.9 5.5 7.3 0.1 3.4 3 1 0 3 3 3 0 Bacterial protein of unknown function (DUF948) Sas10_Utp3 PF04000.15 OQR98385.1 - 5.6 7.7 8.1 33 5.2 3.4 3.5 2 1 0 2 2 2 0 Sas10/Utp3/C1D family Laminin_II PF06009.12 OQR98385.1 - 7.6 6.5 15.7 4 7.5 3.4 3.1 1 1 0 2 2 2 0 Laminin Domain II XAP5 PF04921.14 OQR98386.1 - 1.1e-66 225.2 9.5 1.1e-66 225.2 9.5 2.0 1 1 0 2 2 2 1 XAP5, circadian clock regulator CxC5 PF18718.1 OQR98386.1 - 0.1 12.7 0.0 0.18 11.9 0.0 1.4 1 0 0 1 1 1 0 CxC5 like cysteine cluster associated with KDZ transposases Gemin6 PF06372.12 OQR98386.1 - 4.3 6.8 5.6 0.66 9.5 0.4 2.2 3 0 0 3 3 3 0 Gemin6 protein WGG PF10273.9 OQR98388.1 - 3.7e-18 66.0 0.1 5.5e-18 65.4 0.1 1.3 1 0 0 1 1 1 1 Pre-rRNA-processing protein TSR2 CAGE1 PF15066.6 OQR98388.1 - 0.24 10.0 2.3 0.22 10.2 1.2 1.4 1 1 1 2 2 2 0 Cancer-associated gene protein 1 family DUF4211 PF13926.6 OQR98389.1 - 0.094 12.8 5.3 0.13 12.3 0.9 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4211) FAM76 PF16046.5 OQR98389.1 - 0.18 11.1 14.6 0.29 10.4 14.6 1.4 1 0 0 1 1 1 0 FAM76 protein NPV_P10 PF05531.12 OQR98389.1 - 0.38 11.2 9.4 0.94 10.0 0.7 2.6 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein BLOC1_2 PF10046.9 OQR98389.1 - 1.3 9.3 11.8 5 7.5 1.3 2.7 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 BPL_N PF09825.9 OQR98389.1 - 1.4 7.9 9.0 1.9 7.5 9.0 1.1 1 0 0 1 1 1 0 Biotin-protein ligase, N terminal Jnk-SapK_ap_N PF09744.9 OQR98389.1 - 4.4 7.5 24.0 0.52 10.5 12.1 2.3 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 APG6_N PF17675.1 OQR98389.1 - 6 7.4 19.7 0.27 11.8 6.9 2.4 3 0 0 3 3 3 0 Apg6 coiled-coil region Ribosomal_L4 PF00573.22 OQR98390.1 - 2.3e-68 229.7 1.0 2.8e-68 229.4 1.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family PALP PF00291.25 OQR98391.1 - 5.8e-84 282.0 9.7 2.2e-46 158.6 1.7 2.2 2 0 0 2 2 2 2 Pyridoxal-phosphate dependent enzyme DUF1971 PF09313.11 OQR98391.1 - 0.0024 17.9 0.0 0.93 9.6 0.0 2.7 2 0 0 2 2 2 2 Domain of unknown function (DUF1971) GKAP PF03359.13 OQR98391.1 - 1.1 8.8 0.0 1.1 8.8 0.0 2.5 2 1 0 2 2 2 0 Guanylate-kinase-associated protein (GKAP) protein Rdx PF10262.9 OQR98392.1 - 5.5e-05 23.3 0.0 7.9e-05 22.8 0.0 1.4 1 1 0 1 1 1 1 Rdx family DUF2798 PF11391.8 OQR98392.1 - 0.044 13.8 2.7 0.073 13.1 2.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2798) Hox9_act PF04617.13 OQR98393.1 - 0.81 10.4 11.9 4.5 8.0 0.2 3.8 4 0 0 4 4 4 0 Hox9 activation region p450 PF00067.22 OQR98394.1 - 2.4e-136 455.2 0.3 3.7e-77 260.0 0.0 2.8 3 0 0 3 3 3 2 Cytochrome P450 Myb_DNA-binding PF00249.31 OQR98394.1 - 8.3e-13 48.3 0.1 8.3e-13 48.3 0.1 1.9 2 0 0 2 2 2 1 Myb-like DNA-binding domain LRR_6 PF13516.6 OQR98394.1 - 1.3e-07 31.1 25.5 0.1 12.7 0.2 8.4 10 0 0 10 10 10 3 Leucine Rich repeat LRR_4 PF12799.7 OQR98394.1 - 5.6e-07 29.8 18.9 0.016 15.6 0.0 6.3 5 2 1 6 6 6 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 OQR98394.1 - 6.3e-05 22.7 7.4 0.02 14.7 0.2 3.8 4 0 0 4 4 4 2 Leucine rich repeat IQ PF00612.27 OQR98394.1 - 0.0013 18.4 0.3 0.0013 18.4 0.3 16.5 18 0 0 18 18 18 6 IQ calmodulin-binding motif Myb_DNA-bind_7 PF15963.5 OQR98394.1 - 0.011 15.7 0.2 0.034 14.0 0.2 1.8 1 0 0 1 1 1 0 Myb DNA-binding like Myb_DNA-bind_6 PF13921.6 OQR98394.1 - 0.013 15.8 0.1 0.039 14.2 0.1 1.9 1 0 0 1 1 1 0 Myb-like DNA-binding domain LRR_1 PF00560.33 OQR98394.1 - 2.5 9.0 22.6 31 5.7 2.5 7.9 7 1 0 7 7 7 0 Leucine Rich Repeat Ank_2 PF12796.7 OQR98395.1 - 8.9e-123 401.2 23.1 3.7e-19 69.1 0.1 8.1 1 1 8 10 10 10 10 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQR98395.1 - 2.2e-101 331.0 10.1 8.7e-12 45.3 0.0 10.6 2 1 9 12 12 12 12 Ankyrin repeats (many copies) Ank PF00023.30 OQR98395.1 - 1.6e-88 287.6 4.0 1.2e-06 28.7 0.0 14.4 15 0 0 15 15 15 13 Ankyrin repeat Ank_3 PF13606.6 OQR98395.1 - 1.1e-71 228.1 0.2 0.00039 20.6 0.0 15.0 15 0 0 15 15 15 12 Ankyrin repeat Ank_5 PF13857.6 OQR98395.1 - 3.1e-66 218.6 6.0 9.2e-10 38.6 0.1 10.6 4 4 7 11 11 11 10 Ankyrin repeats (many copies) EccE PF11203.8 OQR98395.1 - 0.0024 18.2 0.0 16 5.9 0.0 4.3 2 2 2 4 4 4 0 Putative type VII ESX secretion system translocon, EccE DUF2520 PF10728.9 OQR98395.1 - 0.0066 16.2 6.6 12 5.7 0.3 5.4 2 2 3 5 5 5 2 Domain of unknown function (DUF2520) Glyoxalase_6 PF18029.1 OQR98395.1 - 0.01 16.6 9.5 2.3 9.0 0.9 5.5 4 2 0 4 4 4 0 Glyoxalase-like domain adh_short PF00106.25 OQR98395.1 - 0.014 14.8 1.4 0.52 9.7 0.1 3.3 2 2 3 5 5 5 0 short chain dehydrogenase Ser_hydrolase PF06821.13 OQR98395.1 - 0.021 14.7 5.4 39 4.1 0.0 5.4 3 3 5 8 8 8 0 Serine hydrolase Orn_Arg_deC_N PF02784.16 OQR98395.1 - 0.029 13.7 0.2 6.8 6.0 0.0 4.3 4 1 0 5 5 5 0 Pyridoxal-dependent decarboxylase, pyridoxal binding domain FmdA_AmdA PF03069.15 OQR98395.1 - 0.046 12.6 0.0 44 2.8 0.0 4.4 2 1 1 4 4 4 0 Acetamidase/Formamidase family Imm2 PF14426.6 OQR98395.1 - 5.7 7.1 6.8 49 4.1 0.0 5.3 7 1 0 7 7 7 0 Immunity protein Imm2 PCI PF01399.27 OQR98396.1 - 4.1e-17 62.6 0.2 1e-16 61.3 0.2 1.7 1 0 0 1 1 1 1 PCI domain TPR_MalT PF17874.1 OQR98396.1 - 0.0093 15.4 0.0 0.13 11.7 0.0 2.2 2 0 0 2 2 2 1 MalT-like TPR region TPR_14 PF13428.6 OQR98396.1 - 0.0098 16.6 0.2 6.5 7.9 0.0 3.6 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.6 OQR98396.1 - 0.016 15.2 1.4 0.5 10.5 0.0 3.9 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_1 PF00515.28 OQR98396.1 - 0.057 13.3 1.6 39 4.3 0.2 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_11 PF13414.6 OQR98396.1 - 0.077 12.7 0.1 70 3.2 0.1 4.2 5 0 0 5 5 5 0 TPR repeat TPR_2 PF07719.17 OQR98396.1 - 0.23 11.7 2.4 16 5.9 0.0 4.2 5 0 0 5 5 5 0 Tetratricopeptide repeat PseudoU_synth_1 PF01416.20 OQR98397.1 - 6.5e-27 94.1 0.0 7.5e-16 58.5 0.0 2.1 2 0 0 2 2 2 2 tRNA pseudouridine synthase DIOX_N PF14226.6 OQR98398.1 - 2.7e-21 76.5 0.0 4.6e-21 75.8 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 OQR98398.1 - 1.4e-12 48.0 0.0 2.5e-12 47.2 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily PseudoU_synth_2 PF00849.22 OQR98399.1 - 1.5e-15 57.7 0.0 1.2e-14 54.7 0.0 2.1 1 1 0 1 1 1 1 RNA pseudouridylate synthase S4 PF01479.25 OQR98399.1 - 8.7e-12 44.6 0.4 2.9e-11 42.9 0.4 2.0 1 0 0 1 1 1 1 S4 domain S4_2 PF13275.6 OQR98399.1 - 0.054 13.3 0.0 0.15 11.9 0.0 1.7 1 0 0 1 1 1 0 S4 domain DUF2633 PF11119.8 OQR98400.1 - 0.053 13.4 0.0 0.085 12.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2633) DIOX_N PF14226.6 OQR98401.1 - 8.1e-22 78.2 0.0 1.2e-21 77.6 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 OQR98401.1 - 4.4e-12 46.4 0.0 7.4e-12 45.6 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Pro_isomerase PF00160.21 OQR98402.1 - 5.7e-22 78.7 0.1 7e-22 78.4 0.1 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD GCV_T PF01571.21 OQR98403.1 - 1.9e-81 273.2 0.0 3e-81 272.6 0.0 1.3 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.11 OQR98403.1 - 6e-19 67.7 0.1 1.4e-18 66.6 0.1 1.6 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain SoxG PF04268.12 OQR98403.1 - 0.11 12.6 0.0 0.57 10.3 0.0 2.1 2 1 1 3 3 3 0 Sarcosine oxidase, gamma subunit family DUF485 PF04341.12 OQR98404.1 - 0.087 12.8 2.1 0.099 12.6 1.9 1.3 1 1 0 1 1 1 0 Protein of unknown function, DUF485 NEMP PF10225.9 OQR98406.1 - 5 6.7 11.6 0.23 11.1 3.0 2.4 1 1 1 2 2 2 0 NEMP family PH PF00169.29 OQR98507.1 - 1.5e-17 64.0 0.1 1.3e-07 32.1 0.0 2.5 2 0 0 2 2 2 2 PH domain PH_11 PF15413.6 OQR98507.1 - 2.9e-07 30.9 5.6 0.0036 17.7 0.1 4.3 4 1 1 5 5 5 2 Pleckstrin homology domain PH_8 PF15409.6 OQR98507.1 - 3e-05 24.2 0.0 8.1e-05 22.8 0.0 1.8 2 0 0 2 2 2 1 Pleckstrin homology domain PH_3 PF14593.6 OQR98507.1 - 0.0061 16.7 0.0 0.06 13.5 0.0 2.3 2 1 0 2 2 2 1 PH domain PH_12 PF16457.5 OQR98507.1 - 0.043 14.3 0.1 0.37 11.3 0.0 2.4 2 0 0 2 2 2 0 Pleckstrin homology domain EMP24_GP25L PF01105.24 OQR98508.1 - 3.7e-18 66.1 0.6 6.3e-09 36.0 0.0 2.4 2 1 0 2 2 2 2 emp24/gp25L/p24 family/GOLD Oxidored_FMN PF00724.20 OQR98531.1 - 2e-41 142.4 0.1 2.3e-41 142.2 0.1 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family AP_endonuc_2 PF01261.24 OQR98531.1 - 0.0058 16.1 0.3 2.6 7.4 0.0 2.1 1 1 1 2 2 2 2 Xylose isomerase-like TIM barrel Ank_2 PF12796.7 OQR98532.1 - 5.2e-30 103.9 21.2 1.8e-07 31.6 0.0 6.4 2 2 5 7 7 7 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQR98532.1 - 2.2e-29 101.4 15.8 6.1e-05 23.5 0.4 9.3 7 3 2 9 9 9 8 Ankyrin repeats (many copies) Ank_5 PF13857.6 OQR98532.1 - 1.2e-19 70.0 16.4 0.0095 16.2 0.1 11.1 4 4 8 12 12 12 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQR98532.1 - 3.6e-17 60.7 9.6 4 8.3 0.0 12.0 10 2 2 12 12 12 4 Ankyrin repeat Ank PF00023.30 OQR98532.1 - 1.9e-05 24.9 9.2 5.9 7.5 0.1 8.1 7 2 1 8 8 8 1 Ankyrin repeat Oxidored_FMN PF00724.20 OQR98533.1 - 2.1e-89 300.2 0.0 2.4e-89 300.0 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Glucan_synthase PF02364.15 OQR98534.1 - 0.075 11.2 0.3 0.23 9.6 0.0 1.7 2 0 0 2 2 2 0 1,3-beta-glucan synthase component Oxidored_FMN PF00724.20 OQR98535.1 - 1e-17 64.5 0.0 1.6e-17 63.8 0.0 1.2 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family NDK PF00334.19 OQR98535.1 - 3.2e-17 62.8 0.0 1.7e-12 47.5 0.0 3.7 4 0 0 4 4 4 3 Nucleoside diphosphate kinase ACT_5 PF13710.6 OQR98535.1 - 0.028 14.2 0.1 2.7 7.9 0.0 2.4 2 0 0 2 2 2 0 ACT domain DUF1726 PF08351.11 OQR98535.1 - 0.17 11.8 0.0 0.41 10.6 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1726) YbjQ_1 PF01906.17 OQR98536.1 - 1.6e-25 89.7 1.4 2.2e-25 89.3 1.4 1.2 1 0 0 1 1 1 1 Putative heavy-metal-binding Pom PF17251.2 OQR98536.1 - 0.16 11.2 0.0 0.21 10.9 0.0 1.1 1 0 0 1 1 1 0 Protochlamydia outer membrane protein Glyco_hydro81C PF17652.1 OQR98537.1 - 5e-116 387.8 6.8 8.7e-116 387.0 6.8 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 C-terminal domain Amidase PF01425.21 OQR98537.1 - 3.9e-84 283.2 0.7 1.1e-83 281.8 0.7 1.7 1 1 0 1 1 1 1 Amidase Glyco_hydro_81 PF03639.13 OQR98537.1 - 9.9e-52 176.1 0.1 1.4e-51 175.6 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 N-terminal domain Peptidase_C1 PF00112.23 OQR98539.1 - 2.9e-57 194.3 11.3 3.9e-57 193.8 11.3 1.1 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.15 OQR98539.1 - 2.9e-06 26.3 0.5 0.0011 17.8 0.0 2.1 2 0 0 2 2 2 2 Peptidase C1-like family CN_hydrolase PF00795.22 OQR98540.1 - 3.3e-26 92.2 0.0 3.2e-14 52.9 0.0 3.1 3 0 0 3 3 3 3 Carbon-nitrogen hydrolase CxC6 PF18721.1 OQR98541.1 - 0.19 12.0 22.2 5.4 7.4 10.4 3.7 1 1 1 2 2 2 0 CxC6 like cysteine cluster associated with KDZ transposases WD40 PF00400.32 OQR98542.1 - 2.3e-06 28.2 3.3 5.9 7.9 0.1 6.6 6 0 0 6 6 6 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OQR98542.1 - 0.074 13.4 0.0 1.5 9.1 0.0 3.1 4 1 0 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain Ricin_B_lectin PF00652.22 OQR98543.1 - 4.4e-28 98.1 16.0 4.7e-14 52.7 2.4 2.7 2 0 0 2 2 2 2 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.6 OQR98543.1 - 9.3e-07 29.5 23.8 0.0065 17.2 6.7 5.2 3 2 2 5 5 5 2 Ricin-type beta-trefoil lectin domain-like DPBB_1 PF03330.18 OQR98543.1 - 3.9e-05 23.8 1.1 0.0003 21.0 0.1 2.4 2 0 0 2 2 2 1 Lytic transglycolase CDtoxinA PF03498.14 OQR98543.1 - 0.0021 17.6 3.0 0.049 13.2 0.2 3.0 1 1 0 2 2 2 1 Cytolethal distending toxin A/C domain DEC-1_N PF04625.13 OQR98543.1 - 0.0022 17.1 7.1 0.0032 16.6 7.1 1.2 1 0 0 1 1 1 1 DEC-1 protein, N-terminal region Totivirus_coat PF05518.11 OQR98543.1 - 0.15 10.1 5.1 0.22 9.5 5.1 1.1 1 0 0 1 1 1 0 Totivirus coat protein B9-C2 PF07162.11 OQR98544.1 - 1.4e-40 139.2 0.1 1.6e-40 139.0 0.1 1.0 1 0 0 1 1 1 1 Ciliary basal body-associated, B9 protein SpoU_methylase PF00588.19 OQR98545.1 - 2.3e-29 102.4 0.0 2.6e-29 102.2 0.0 1.0 1 0 0 1 1 1 1 SpoU rRNA Methylase family Tom22 PF04281.13 OQR98546.1 - 0.026 14.3 0.1 0.043 13.6 0.1 1.3 1 0 0 1 1 1 0 Mitochondrial import receptor subunit Tom22 Sdh_cyt PF01127.22 OQR98547.1 - 1.3e-11 44.6 0.3 1.8e-11 44.1 0.3 1.2 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit Profilin PF00235.19 OQR98547.1 - 0.00061 20.1 0.0 0.0011 19.3 0.0 1.4 1 0 0 1 1 1 1 Profilin Phage_holin_8 PF16931.5 OQR98547.1 - 0.23 11.5 4.4 0.41 10.6 4.4 1.3 1 0 0 1 1 1 0 Putative phage holin DUF4781 PF16013.5 OQR98547.1 - 0.81 8.4 2.6 1.1 8.0 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4781) MIF4G PF02854.19 OQR98724.1 - 1.7e-20 73.6 5.5 5.9e-20 71.8 4.9 2.2 2 0 0 2 2 2 1 MIF4G domain MA3 PF02847.17 OQR98724.1 - 1.9e-18 66.5 1.1 4.2e-18 65.4 0.1 2.2 2 0 0 2 2 2 1 MA3 domain Vac14_Fab1_bd PF12755.7 OQR98724.1 - 0.057 14.0 0.1 1.6 9.4 0.0 2.8 2 0 0 2 2 2 0 Vacuolar 14 Fab1-binding region DUF4746 PF15928.5 OQR98724.1 - 0.24 10.8 8.4 0.72 9.2 8.4 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) SDA1 PF05285.12 OQR98724.1 - 4.6 6.6 24.4 9.8 5.5 24.4 1.5 1 0 0 1 1 1 0 SDA1 AA_kinase PF00696.28 OQR98726.1 - 3.8e-26 92.1 0.2 6.5e-26 91.4 0.2 1.4 1 0 0 1 1 1 1 Amino acid kinase family Semialdhyde_dh PF01118.24 OQR98726.1 - 1.3e-21 77.3 0.1 4.3e-20 72.4 0.0 3.2 3 1 0 3 3 3 1 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.20 OQR98726.1 - 0.0011 19.1 0.0 0.007 16.5 0.0 2.4 2 0 0 2 2 2 1 Dihydrodipicolinate reductase, N-terminus vATP-synt_E PF01991.18 OQR98726.1 - 0.024 14.0 0.0 0.052 13.0 0.0 1.5 1 0 0 1 1 1 0 ATP synthase (E/31 kDa) subunit CPSase_L_D2 PF02786.17 OQR98727.1 - 5.2e-109 362.6 0.8 9.9e-82 273.5 0.1 2.3 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_sm_chain PF00988.22 OQR98727.1 - 1.1e-50 170.7 0.0 3.1e-50 169.3 0.0 1.8 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain GATase PF00117.28 OQR98727.1 - 6.4e-45 153.3 0.0 6.2e-44 150.0 0.0 2.5 2 0 0 2 2 2 1 Glutamine amidotransferase class-I CPSase_L_D3 PF02787.19 OQR98727.1 - 2e-38 131.4 0.1 5.5e-38 130.1 0.1 1.8 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain MGS PF02142.22 OQR98727.1 - 2.6e-17 62.8 0.0 1.8e-16 60.1 0.0 2.5 2 0 0 2 2 2 1 MGS-like domain Dala_Dala_lig_C PF07478.13 OQR98727.1 - 1.9e-15 57.0 0.8 2.5e-07 30.4 0.1 2.4 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 OQR98727.1 - 2.8e-15 56.3 0.2 2.4e-06 27.3 0.0 2.4 2 0 0 2 2 2 2 ATP-grasp domain ATPgrasp_Ter PF15632.6 OQR98727.1 - 9e-09 35.2 0.0 0.0041 16.9 0.0 2.9 2 1 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon Peptidase_C26 PF07722.13 OQR98727.1 - 0.00098 18.9 0.1 0.11 12.2 0.0 2.7 1 1 0 2 2 2 1 Peptidase C26 GARS_A PF01071.19 OQR98727.1 - 0.0024 17.7 1.5 0.06 13.1 0.2 2.6 2 0 0 2 2 2 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATP-grasp_3 PF02655.14 OQR98727.1 - 0.01 15.9 0.0 0.14 12.2 0.0 2.5 2 0 0 2 2 2 0 ATP-grasp domain ATP-grasp_5 PF13549.6 OQR98727.1 - 0.021 14.3 0.9 1.1 8.6 0.1 3.3 3 1 0 3 3 3 0 ATP-grasp domain HTH_23 PF13384.6 OQR98727.1 - 0.12 12.2 0.1 0.61 10.0 0.0 2.2 2 0 0 2 2 2 0 Homeodomain-like domain zf-UBP PF02148.19 OQR98728.1 - 1e-20 73.8 7.1 2.1e-20 72.8 7.1 1.5 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein BRAP2 PF07576.12 OQR98728.1 - 1.4e-17 63.7 0.0 3.1e-17 62.6 0.0 1.5 1 0 0 1 1 1 1 BRCA1-associated protein 2 zf-RING_2 PF13639.6 OQR98728.1 - 4.1e-08 33.4 9.2 4.1e-08 33.4 9.2 2.3 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 OQR98728.1 - 1.8e-07 30.9 7.9 1.8e-07 30.9 7.9 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 OQR98728.1 - 6.8e-05 22.5 3.3 6.8e-05 22.5 3.3 2.2 2 0 0 2 2 2 1 RING-like zinc finger zf-rbx1 PF12678.7 OQR98728.1 - 0.00023 21.4 6.5 0.00023 21.4 6.5 2.1 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 OQR98728.1 - 0.00033 20.4 7.5 0.00033 20.4 7.5 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OQR98728.1 - 0.0006 19.8 4.4 0.0006 19.8 4.4 2.8 1 1 1 2 2 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 OQR98728.1 - 0.0012 18.6 18.8 0.0086 15.9 6.2 2.3 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) HSBP1 PF06825.12 OQR98728.1 - 0.059 13.2 0.0 0.13 12.1 0.0 1.5 1 0 0 1 1 1 0 Heat shock factor binding protein 1 UPF0242 PF06785.11 OQR98728.1 - 0.061 13.4 13.7 0.1 12.7 13.7 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus zf-ANAPC11 PF12861.7 OQR98728.1 - 0.16 12.1 10.2 0.034 14.2 5.9 2.0 2 1 1 3 3 3 0 Anaphase-promoting complex subunit 11 RING-H2 finger DUF390 PF04094.14 OQR98728.1 - 0.78 8.0 4.8 1.1 7.5 4.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF390) zf-Sec23_Sec24 PF04810.15 OQR98728.1 - 1.7 8.7 7.2 11 6.1 4.1 3.1 2 1 0 2 2 2 0 Sec23/Sec24 zinc finger CCDC-167 PF15188.6 OQR98728.1 - 3.6 8.0 17.6 0.12 12.8 8.0 2.8 1 1 2 3 3 3 0 Coiled-coil domain-containing protein 167 Prok-RING_4 PF14447.6 OQR98728.1 - 3.9 7.4 24.1 0.66 9.9 6.3 3.3 2 1 1 3 3 3 0 Prokaryotic RING finger family 4 ZapB PF06005.12 OQR98728.1 - 5.1 7.6 17.6 1.2 9.6 11.5 2.8 2 1 1 3 3 2 0 Cell division protein ZapB Exonuc_VII_L PF02601.15 OQR98728.1 - 7.1 6.1 8.5 9.7 5.7 8.5 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit Borrelia_P83 PF05262.11 OQR98729.1 - 4.5 5.6 46.1 5.1 5.5 46.1 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein Lipase_3 PF01764.25 OQR98730.1 - 2.1e-23 82.7 0.0 4.7e-23 81.6 0.0 1.6 1 0 0 1 1 1 1 Lipase (class 3) DUF2974 PF11187.8 OQR98730.1 - 0.0028 17.2 0.0 0.029 14.0 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF2974) Methyltransf_16 PF10294.9 OQR98731.1 - 2.1e-20 73.2 0.0 3.2e-20 72.6 0.0 1.3 1 0 0 1 1 1 1 Lysine methyltransferase PrmA PF06325.13 OQR98731.1 - 8.4e-07 28.7 0.1 1.1e-06 28.3 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 OQR98731.1 - 7.9e-06 25.5 0.4 2e-05 24.2 0.2 1.8 1 1 1 2 2 2 1 Methyltransferase small domain Methyltransf_25 PF13649.6 OQR98731.1 - 3e-05 24.6 0.1 5.9e-05 23.7 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OQR98731.1 - 0.00013 21.8 0.0 0.00021 21.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OQR98731.1 - 0.00026 20.8 0.0 0.00037 20.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OQR98731.1 - 0.00089 20.0 0.1 0.0014 19.3 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain TehB PF03848.14 OQR98731.1 - 0.0063 15.9 0.0 0.01 15.3 0.0 1.3 1 0 0 1 1 1 1 Tellurite resistance protein TehB Methyltransf_11 PF08241.12 OQR98731.1 - 0.0069 17.0 0.0 0.011 16.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.16 OQR98731.1 - 0.01 15.6 0.0 0.015 15.0 0.0 1.3 1 0 0 1 1 1 1 Met-10+ like-protein Cons_hypoth95 PF03602.15 OQR98731.1 - 0.019 14.6 0.0 0.028 14.0 0.0 1.2 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Cellulase PF00150.18 OQR98732.1 - 3.3e-13 49.7 0.0 1.3e-12 47.7 0.0 1.8 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_cc PF11790.8 OQR98732.1 - 0.019 14.5 0.0 0.033 13.8 0.0 1.5 1 0 0 1 1 1 0 Glycosyl hydrolase catalytic core Nop PF01798.18 OQR98733.1 - 6.6e-89 297.3 0.3 6.6e-89 297.3 0.3 1.6 2 0 0 2 2 2 1 snoRNA binding domain, fibrillarin NOP5NT PF08156.13 OQR98733.1 - 9.5e-21 74.0 1.3 9.5e-21 74.0 1.3 2.5 4 0 0 4 4 4 1 NOP5NT (NUC127) domain Myc_N PF01056.18 OQR98733.1 - 0.0033 17.4 4.1 0.0048 16.8 4.1 1.3 1 0 0 1 1 1 1 Myc amino-terminal region ApbA_C PF08546.11 OQR98733.1 - 0.062 13.5 0.1 0.21 11.8 0.1 1.9 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA C terminal RNA_polI_A34 PF08208.11 OQR98733.1 - 8.1 6.5 31.5 14 5.7 31.5 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 RR_TM4-6 PF06459.12 OQR98733.1 - 9.8 5.9 18.0 17 5.1 18.0 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF3482 PF11981.8 OQR98734.1 - 0.074 12.4 1.0 0.15 11.4 0.6 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3482) EamA PF00892.20 OQR98734.1 - 0.83 9.8 5.9 0.21 11.7 1.7 2.0 2 1 0 2 2 2 0 EamA-like transporter family Mito_carr PF00153.27 OQR98734.1 - 1.1 9.2 7.9 11 6.0 0.0 4.2 6 0 0 6 6 6 0 Mitochondrial carrier protein Ank_4 PF13637.6 OQR98756.1 - 1.6e-07 31.7 0.0 4.7e-07 30.2 0.0 1.8 1 1 0 1 1 1 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 OQR98756.1 - 2.2e-06 27.9 0.4 0.00094 19.4 0.1 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 OQR98756.1 - 5.6e-05 23.6 0.2 0.00013 22.5 0.2 1.7 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OQR98756.1 - 0.00014 22.0 0.2 0.14 12.7 0.0 3.5 4 0 0 4 4 4 1 Ankyrin repeat EII-Sor PF03609.14 OQR98756.1 - 0.075 12.4 0.0 0.13 11.6 0.0 1.3 2 0 0 2 2 2 0 PTS system sorbose-specific iic component RhodobacterPufX PF11511.8 OQR98757.1 - 0.095 12.3 0.2 0.37 10.4 0.2 1.9 1 0 0 1 1 1 0 Intrinsic membrane protein PufX Tmemb_18A PF09771.9 OQR98757.1 - 0.62 10.5 3.2 0.22 12.0 0.3 1.8 2 1 0 2 2 2 0 Transmembrane protein 188 Ank_2 PF12796.7 OQR98758.1 - 1.4e-19 70.5 2.5 2.9e-08 34.2 0.0 2.4 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OQR98758.1 - 9.1e-18 64.1 0.5 0.00065 20.0 0.0 4.4 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_4 PF13637.6 OQR98758.1 - 6.7e-15 55.3 0.3 2.6e-06 27.8 0.1 3.2 3 2 1 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQR98758.1 - 1.8e-09 37.0 0.1 1.2 10.0 0.0 4.8 4 1 1 5 5 5 3 Ankyrin repeat DUF5049 PF16468.5 OQR98758.1 - 8.3e-05 22.4 0.1 3.2 7.7 0.0 3.9 2 1 2 4 4 4 2 Domain of unknown function (DUF5049) Ank PF00023.30 OQR98758.1 - 0.00052 20.4 0.1 4.7 7.8 0.3 4.5 2 2 1 3 3 3 1 Ankyrin repeat MatE PF01554.18 OQR98759.1 - 3.7e-36 124.2 37.9 9.1e-19 67.7 12.6 2.7 3 0 0 3 3 3 2 MatE Ank_2 PF12796.7 OQR98761.1 - 4.7e-06 27.1 0.1 0.0002 21.9 0.1 2.1 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OQR98761.1 - 1.4e-05 25.2 0.1 0.0042 17.4 0.0 3.6 1 1 3 4 4 4 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 OQR98761.1 - 0.014 15.9 0.2 2.3 8.9 0.0 3.2 3 1 0 3 3 3 0 Ankyrin repeats (many copies) PI3_PI4_kinase PF00454.27 OQR98763.1 - 2e-41 142.4 0.0 3e-41 141.9 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.20 OQR98763.1 - 1.4e-09 37.5 0.0 3.2e-09 36.4 0.0 1.6 1 0 0 1 1 1 1 FATC domain Ank_4 PF13637.6 OQR98764.1 - 8.6e-07 29.4 0.0 0.00014 22.3 0.0 2.5 1 1 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 OQR98764.1 - 8.9e-07 29.4 0.1 6.4e-06 26.7 0.1 1.9 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) DUF5049 PF16468.5 OQR98764.1 - 3.6e-06 26.8 0.2 0.21 11.5 0.0 3.3 1 1 2 3 3 3 3 Domain of unknown function (DUF5049) Ank_5 PF13857.6 OQR98764.1 - 0.00026 21.2 0.0 0.75 10.2 0.0 2.8 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQR98764.1 - 0.00039 20.6 0.0 1.8 9.4 0.0 3.0 3 0 0 3 3 3 2 Ankyrin repeat FAM195 PF14799.6 OQR98764.1 - 0.0035 17.7 0.6 0.64 10.4 0.1 2.8 1 1 2 3 3 3 1 FAM195 family Ank_2 PF12796.7 OQR98765.1 - 1.1e-52 176.5 41.5 8.1e-09 35.9 0.1 8.8 2 2 8 10 10 10 10 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQR98765.1 - 1.3e-51 172.3 18.3 4.5e-07 30.3 0.0 12.4 7 4 5 12 12 12 11 Ankyrin repeats (many copies) Ank_5 PF13857.6 OQR98765.1 - 3.2e-45 151.6 12.6 0.0037 17.5 0.0 16.0 5 3 12 17 17 17 13 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQR98765.1 - 4.7e-31 103.3 3.4 1.1 10.1 0.0 17.1 19 0 0 19 19 19 5 Ankyrin repeat DUF5049 PF16468.5 OQR98765.1 - 5.2e-12 45.5 19.8 2.1 8.3 0.0 13.3 6 2 9 15 15 15 4 Domain of unknown function (DUF5049) FAM195 PF14799.6 OQR98765.1 - 7.7e-08 32.6 4.7 9.5 6.6 0.2 8.1 3 2 3 6 6 6 2 FAM195 family Ank PF00023.30 OQR98765.1 - 5e-05 23.5 5.5 97 3.7 0.0 9.9 7 3 2 9 9 9 0 Ankyrin repeat TBPIP PF07106.13 OQR98765.1 - 0.024 14.6 0.1 59 3.7 0.0 5.0 4 1 1 5 5 5 0 TBPIP/Hop2 winged helix domain Baculo_LEF5_C PF11792.8 OQR98765.1 - 0.034 13.8 9.0 3.6 7.3 0.1 5.5 4 2 2 6 6 6 0 Baculoviridae late expression factor 5 C-terminal domain Ret2_MD PF18528.1 OQR98765.1 - 0.17 12.3 0.9 15 6.1 0.1 3.6 2 2 2 4 4 4 0 RNA editing 3' terminal uridylyl transferase 2 middle domain zf-RING_2 PF13639.6 OQR98766.1 - 3.1e-13 49.8 7.1 3.1e-13 49.8 7.1 3.1 3 0 0 3 3 3 1 Ring finger domain zf-RING_5 PF14634.6 OQR98766.1 - 1e-07 31.7 4.0 3.7e-07 30.0 4.0 2.0 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_11 PF17123.5 OQR98766.1 - 1.1e-07 31.5 7.5 2.3e-07 30.4 6.5 2.2 2 0 0 2 2 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 OQR98766.1 - 1.1e-07 31.6 8.1 3.8e-07 29.8 8.1 2.1 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) PX PF00787.24 OQR98766.1 - 1.4e-07 31.5 0.7 4.8e-07 29.8 0.7 1.9 1 0 0 1 1 1 1 PX domain zf-RING_UBOX PF13445.6 OQR98766.1 - 2.2e-07 30.8 5.0 2.2e-07 30.8 5.0 2.3 2 0 0 2 2 1 1 RING-type zinc-finger zf-rbx1 PF12678.7 OQR98766.1 - 3.8e-07 30.3 5.3 3.8e-07 30.3 5.3 2.4 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-C3HC4_3 PF13920.6 OQR98766.1 - 1.1e-06 28.4 4.6 3.2e-06 26.9 4.6 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 OQR98766.1 - 1.8e-06 27.7 9.0 2.6e-06 27.2 7.5 2.2 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) VPS9 PF02204.18 OQR98766.1 - 6.9e-06 26.2 0.2 4.1e-05 23.7 0.1 2.4 2 0 0 2 2 2 1 Vacuolar sorting protein 9 (VPS9) domain Prok-RING_4 PF14447.6 OQR98766.1 - 0.00095 19.0 7.3 0.0022 17.8 6.7 2.0 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 OQR98766.1 - 0.0019 18.2 3.0 0.0019 18.2 3.0 2.3 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger DDT PF02791.17 OQR98766.1 - 0.0039 17.5 0.4 1.5 9.2 0.0 3.0 2 0 0 2 2 2 1 DDT domain U-box PF04564.15 OQR98766.1 - 0.11 12.7 0.0 0.43 10.8 0.0 2.1 2 0 0 2 2 1 0 U-box domain PrkA PF06798.12 OQR98766.1 - 0.19 11.3 0.5 0.32 10.6 0.5 1.2 1 0 0 1 1 1 0 PrkA serine protein kinase C-terminal domain Zn_ribbon_17 PF17120.5 OQR98766.1 - 0.24 11.0 11.7 0.021 14.5 5.3 2.4 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type FANCL_C PF11793.8 OQR98766.1 - 0.56 10.4 5.5 18 5.6 6.5 2.9 2 1 0 2 2 2 0 FANCL C-terminal domain Prok-RING_1 PF14446.6 OQR98766.1 - 0.59 10.1 8.0 1.1 9.3 3.7 2.8 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 zf-H2C2_2 PF13465.6 OQR98766.1 - 1.8 9.2 9.0 3.4 8.3 0.3 3.2 3 0 0 3 3 2 0 Zinc-finger double domain zf-C3H2C3 PF17122.5 OQR98766.1 - 8.9 6.4 13.5 0.29 11.2 7.0 2.0 2 0 0 2 2 1 0 Zinc-finger V-SNARE PF05008.15 OQR98767.1 - 5.3e-17 62.0 3.3 5.3e-17 62.0 3.3 1.9 2 1 0 2 2 2 1 Vesicle transport v-SNARE protein N-terminus V-SNARE_C PF12352.8 OQR98767.1 - 1.6e-07 31.5 2.2 1.6e-07 31.5 2.2 2.5 2 1 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.13 OQR98767.1 - 1.3e-06 28.3 6.9 1.5e-05 24.8 0.2 3.6 1 1 4 5 5 5 1 Sec20 DUF1664 PF07889.12 OQR98767.1 - 0.0023 17.9 8.6 0.27 11.3 0.3 2.6 2 1 0 2 2 2 2 Protein of unknown function (DUF1664) Tropomyosin PF00261.20 OQR98767.1 - 0.0057 16.1 12.9 0.02 14.3 2.6 2.1 1 1 1 2 2 2 1 Tropomyosin Spc7 PF08317.11 OQR98767.1 - 0.015 14.2 7.5 0.024 13.6 7.5 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein AAA_13 PF13166.6 OQR98767.1 - 0.022 13.4 6.1 0.031 12.9 6.1 1.2 1 0 0 1 1 1 0 AAA domain DUF1640 PF07798.11 OQR98767.1 - 0.028 14.5 9.8 0.048 13.7 9.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) RPW8 PF05659.11 OQR98767.1 - 0.028 14.1 3.6 0.033 13.9 1.3 2.1 1 1 1 2 2 2 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 Laminin_II PF06009.12 OQR98767.1 - 0.038 14.0 10.6 0.39 10.7 1.0 2.6 1 1 0 2 2 2 0 Laminin Domain II TOM20_plant PF06552.12 OQR98767.1 - 0.051 13.3 0.5 0.68 9.7 0.1 2.1 1 1 1 2 2 2 0 Plant specific mitochondrial import receptor subunit TOM20 FUSC PF04632.12 OQR98767.1 - 0.065 11.8 0.5 0.077 11.5 0.5 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family Fib_alpha PF08702.10 OQR98767.1 - 0.073 13.3 8.9 0.12 12.5 3.4 2.2 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family DUF2408 PF10303.9 OQR98767.1 - 0.078 13.5 4.7 0.14 12.8 4.4 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2408) Exonuc_VII_L PF02601.15 OQR98767.1 - 0.084 12.4 10.0 0.13 11.8 10.0 1.4 1 1 0 1 1 1 0 Exonuclease VII, large subunit DUF4208 PF13907.6 OQR98767.1 - 0.091 13.2 2.4 0.21 12.0 0.6 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF4208) PRT_C PF08372.10 OQR98767.1 - 0.15 11.9 0.2 1.6 8.5 0.0 2.2 2 0 0 2 2 2 0 Plant phosphoribosyltransferase C-terminal HrpB7 PF09486.10 OQR98767.1 - 0.16 12.4 14.2 0.097 13.1 3.8 2.2 1 1 1 2 2 2 0 Bacterial type III secretion protein (HrpB7) BLOC1_2 PF10046.9 OQR98767.1 - 0.21 11.9 10.8 1.6 9.1 0.4 3.2 2 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 CcdA PF07362.12 OQR98767.1 - 0.34 11.4 5.6 4 7.9 0.4 2.7 2 1 0 2 2 2 0 Post-segregation antitoxin CcdA Cauli_AT PF03233.13 OQR98767.1 - 0.44 10.4 3.9 0.91 9.4 1.1 2.1 2 0 0 2 2 2 0 Aphid transmission protein DUF4854 PF16146.5 OQR98767.1 - 0.63 10.4 3.9 2.8 8.3 0.3 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF4854) XhlA PF10779.9 OQR98767.1 - 0.67 10.2 7.9 13 6.1 1.4 3.2 2 1 1 3 3 3 0 Haemolysin XhlA DUF2203 PF09969.9 OQR98767.1 - 0.7 10.6 9.5 29 5.4 6.0 2.7 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) Noelin-1 PF12308.8 OQR98767.1 - 0.72 9.9 4.0 2.1 8.4 0.5 2.3 2 0 0 2 2 2 0 Neurogenesis glycoprotein Nup54 PF13874.6 OQR98767.1 - 0.75 9.9 8.3 0.78 9.8 6.4 1.9 1 1 0 2 2 2 0 Nucleoporin complex subunit 54 Cytochrom_B562 PF07361.11 OQR98767.1 - 0.81 10.4 6.5 0.77 10.4 3.4 2.2 1 1 1 2 2 2 0 Cytochrome b562 ArAE_2_N PF10337.9 OQR98767.1 - 1.2 8.1 4.6 0.9 8.5 3.8 1.3 1 1 0 1 1 1 0 Putative ER transporter, 6TM, N-terminal DUF16 PF01519.16 OQR98767.1 - 1.2 9.7 9.9 5.8 7.5 0.9 2.3 1 1 1 2 2 2 0 Protein of unknown function DUF16 NPV_P10 PF05531.12 OQR98767.1 - 1.5 9.3 5.0 10 6.7 0.8 3.0 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein TEX13 PF15186.6 OQR98767.1 - 1.8 8.3 8.0 1.8 8.2 4.4 2.1 1 1 1 2 2 2 0 Testis-expressed sequence 13 protein family Syntaxin-6_N PF09177.11 OQR98767.1 - 2.1 9.0 8.8 34 5.1 8.8 2.5 1 1 0 1 1 1 0 Syntaxin 6, N-terminal Occludin_ELL PF07303.13 OQR98767.1 - 5.3 7.8 8.7 38 5.1 0.5 3.0 2 1 0 3 3 3 0 Occludin homology domain DUF2205 PF10224.9 OQR98767.1 - 6.5 6.8 9.0 0.91 9.6 2.0 2.8 1 1 1 2 2 2 0 Short coiled-coil protein HAUS6_N PF14661.6 OQR98767.1 - 10 5.7 9.8 36 3.8 9.7 2.0 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus DUF2500 PF10694.9 OQR98768.1 - 0.11 13.0 0.1 0.2 12.2 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2500) Kazal_2 PF07648.15 OQR98769.1 - 1e-15 57.6 14.5 2.2e-08 34.1 4.1 2.5 2 0 0 2 2 2 2 Kazal-type serine protease inhibitor domain Kazal_1 PF00050.21 OQR98769.1 - 1.1e-13 50.9 15.4 1.7e-08 34.3 4.0 2.4 2 0 0 2 2 2 2 Kazal-type serine protease inhibitor domain Casein PF00363.18 OQR98769.1 - 0.071 13.5 0.1 0.11 12.8 0.1 1.3 1 0 0 1 1 1 0 Casein SPRY PF00622.28 OQR98770.1 - 1.3e-07 31.8 0.9 4.4e-07 30.0 0.0 2.1 2 2 0 2 2 2 1 SPRY domain FHA PF00498.26 OQR98771.1 - 1.5e-19 70.1 0.0 4.1e-19 68.7 0.0 1.8 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 OQR98771.1 - 4.3e-09 36.6 0.0 4.4e-08 33.3 0.0 2.8 2 0 0 2 2 2 1 Inner membrane component of T3SS, cytoplasmic domain Pkinase PF00069.25 OQR98773.1 - 7.5e-104 346.8 3.8 1.3e-65 221.4 0.2 3.1 2 1 1 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 OQR98773.1 - 1.8e-44 152.0 3.5 2.1e-31 109.1 0.1 3.4 2 1 1 3 3 3 3 Protein tyrosine kinase Imm7 PF15585.6 OQR98773.1 - 5.6e-05 23.4 0.0 0.61 10.4 0.0 2.5 2 0 0 2 2 2 2 Immunity protein 7 Kdo PF06293.14 OQR98773.1 - 0.00025 20.5 0.1 0.00051 19.5 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 OQR98773.1 - 0.026 14.2 1.8 2.3 7.8 0.3 3.0 2 1 1 3 3 3 0 Kinetochore Sim4 complex subunit FTA2 PP28 PF10252.9 OQR98773.1 - 0.03 14.8 0.2 12 6.5 0.0 2.4 2 0 0 2 2 2 0 Casein kinase substrate phosphoprotein PP28 Psb28 PF03912.14 OQR98773.1 - 0.048 13.9 0.8 1.7 9.0 0.2 2.6 2 0 0 2 2 2 0 Psb28 protein SIS_2 PF13580.6 OQR98773.1 - 0.054 13.5 0.0 0.9 9.6 0.0 2.4 2 0 0 2 2 2 0 SIS domain Kinase-like PF14531.6 OQR98773.1 - 0.15 11.4 0.4 0.85 8.9 0.0 2.4 3 1 0 3 3 3 0 Kinase-like DNA_ligase_A_C PF04679.15 OQR98773.1 - 0.17 12.5 0.0 22 5.7 0.0 3.0 3 0 0 3 3 3 0 ATP dependent DNA ligase C terminal region HEAT_2 PF13646.6 OQR98773.1 - 0.21 12.0 0.0 23 5.4 0.0 2.4 2 0 0 2 2 2 0 HEAT repeats FlgT_N PF16548.5 OQR98773.1 - 0.33 11.5 0.9 4.7 7.8 0.1 2.3 2 0 0 2 2 2 0 Flagellar assembly protein T, N-terminal domain BTB_2 PF02214.22 OQR98774.1 - 3.4e-14 52.9 0.1 9.1e-14 51.6 0.0 1.7 2 0 0 2 2 2 1 BTB/POZ domain Thiolase_N PF00108.23 OQR98775.1 - 7.7e-99 330.3 0.1 1.1e-98 329.8 0.1 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 OQR98775.1 - 3.7e-44 149.3 6.5 5.7e-44 148.7 1.1 2.5 3 0 0 3 3 3 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 OQR98775.1 - 4.7e-07 29.6 3.3 4.5e-06 26.4 1.4 2.6 1 1 1 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.10 OQR98775.1 - 0.011 15.6 2.6 1.2 9.0 0.0 3.4 3 0 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Ank_2 PF12796.7 OQR98776.1 - 3.5e-24 85.2 0.4 9.9e-12 45.3 0.0 3.7 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQR98776.1 - 8.5e-16 58.1 0.6 1.8e-06 28.4 0.0 4.7 3 2 2 5 5 5 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQR98776.1 - 3.8e-15 54.5 0.1 0.001 19.3 0.0 6.7 6 0 0 6 6 6 2 Ankyrin repeat Ank_5 PF13857.6 OQR98776.1 - 2.5e-14 53.2 2.0 0.0022 18.3 0.1 6.3 2 2 4 6 6 6 3 Ankyrin repeats (many copies) UPF0020 PF01170.18 OQR98776.1 - 9.9e-13 48.2 0.1 5.9e-06 26.1 0.1 2.4 2 0 0 2 2 2 2 Putative RNA methylase family UPF0020 Ank PF00023.30 OQR98776.1 - 1e-08 35.2 0.2 0.049 14.1 0.0 5.2 5 1 0 5 5 5 2 Ankyrin repeat N6_N4_Mtase PF01555.18 OQR98776.1 - 0.00024 20.9 0.0 0.12 12.1 0.0 2.4 2 0 0 2 2 2 2 DNA methylase MTS PF05175.14 OQR98776.1 - 0.0035 16.9 0.0 0.0082 15.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain N6-adenineMlase PF10237.9 OQR98776.1 - 0.0074 16.1 0.3 0.019 14.7 0.0 1.9 2 1 1 3 3 3 1 Probable N6-adenine methyltransferase N6_Mtase PF02384.16 OQR98776.1 - 0.0074 15.6 0.0 0.12 11.6 0.0 2.1 1 1 0 1 1 1 1 N-6 DNA Methylase Asp_Glu_race PF01177.22 OQR98830.1 - 2.3e-25 89.8 0.0 2.8e-25 89.5 0.0 1.1 1 0 0 1 1 1 1 Asp/Glu/Hydantoin racemase PKcGMP_CC PF16808.5 OQR98831.1 - 0.022 14.6 0.0 0.088 12.7 0.0 1.9 2 0 0 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase RasGEF PF00617.19 OQR98831.1 - 0.042 14.1 0.7 0.1 12.8 0.7 2.0 1 1 0 1 1 1 0 RasGEF domain UFD1 PF03152.14 OQR98833.1 - 8.4e-74 246.8 0.0 1e-73 246.5 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 DUF5088 PF17008.5 OQR98833.1 - 0.21 11.3 0.0 0.35 10.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5088) WD40 PF00400.32 OQR98834.1 - 9.3e-09 35.8 4.1 0.0045 17.8 0.2 4.8 5 0 0 5 5 5 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OQR98834.1 - 0.008 16.5 0.0 5.2 7.4 0.0 3.9 2 1 0 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 OQR98834.1 - 0.013 15.4 0.1 0.16 11.8 0.0 2.4 1 1 1 2 2 2 0 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 OQR98834.1 - 0.064 12.6 0.2 0.21 10.9 0.1 1.8 1 1 0 1 1 1 0 WD40-like domain TMCO5 PF14992.6 OQR98834.1 - 0.073 12.6 0.5 0.15 11.6 0.5 1.5 1 0 0 1 1 1 0 TMCO5 family Abhydrolase_2 PF02230.16 OQR98835.1 - 5.2e-13 49.3 0.0 6.4e-13 49.0 0.0 1.1 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_3 PF07859.13 OQR98835.1 - 0.0034 17.3 0.0 0.0036 17.2 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold DLH PF01738.18 OQR98835.1 - 0.0056 16.3 0.0 0.0076 15.8 0.0 1.2 1 0 0 1 1 1 1 Dienelactone hydrolase family Pkinase PF00069.25 OQR98836.1 - 1.5e-71 240.9 0.0 2.5e-71 240.2 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQR98836.1 - 5.7e-39 134.0 0.0 9e-39 133.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase CDT1 PF08839.11 OQR98836.1 - 1.5e-12 48.2 0.3 6.9e-12 46.0 0.3 2.1 1 1 0 1 1 1 1 DNA replication factor CDT1 like CDT1_C PF16679.5 OQR98836.1 - 7e-06 26.4 0.9 7e-06 26.4 0.9 2.9 3 0 0 3 3 3 1 DNA replication factor Cdt1 C-terminal domain Kdo PF06293.14 OQR98836.1 - 3.3e-05 23.3 0.0 7.8e-05 22.1 0.0 1.6 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 OQR98836.1 - 0.0022 16.8 0.0 0.0052 15.6 0.0 1.5 1 0 0 1 1 1 1 Fungal protein kinase DUF2985 PF11204.8 OQR98837.1 - 1.9e-10 40.8 1.7 1.9e-10 40.8 1.7 2.0 2 1 0 2 2 2 1 Protein of unknown function (DUF2985) DUF2368 PF10166.9 OQR98837.1 - 2.3 7.8 5.2 1.1 8.9 1.7 2.1 2 1 1 3 3 3 0 Uncharacterised conserved protein (DUF2368) AAA_31 PF13614.6 OQR98871.1 - 2.7e-15 56.7 0.1 6.5e-15 55.5 0.1 1.5 1 1 0 1 1 1 1 AAA domain CbiA PF01656.23 OQR98871.1 - 4.4e-12 46.2 0.1 5.6e-12 45.8 0.1 1.3 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ParA PF10609.9 OQR98871.1 - 1.9e-11 43.9 0.6 3.7e-11 42.9 0.6 1.6 1 1 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase ArsA_ATPase PF02374.15 OQR98871.1 - 1.9e-09 37.2 1.2 5.2e-09 35.7 0.6 1.7 2 0 0 2 2 2 1 Anion-transporting ATPase MipZ PF09140.11 OQR98871.1 - 4.6e-08 32.7 0.1 8.7e-08 31.8 0.1 1.5 1 1 0 1 1 1 1 ATPase MipZ CBP_BcsQ PF06564.12 OQR98871.1 - 3.1e-05 23.6 0.1 0.0003 20.4 0.1 2.0 1 1 0 1 1 1 1 Cellulose biosynthesis protein BcsQ AAA_24 PF13479.6 OQR98871.1 - 3.2e-05 23.8 0.0 4.2e-05 23.3 0.0 1.1 1 0 0 1 1 1 1 AAA domain CLP1_P PF16575.5 OQR98871.1 - 0.019 14.8 0.1 0.031 14.1 0.1 1.3 1 0 0 1 1 1 0 mRNA cleavage and polyadenylation factor CLP1 P-loop MeaB PF03308.16 OQR98871.1 - 0.053 12.5 0.8 0.079 11.9 0.5 1.4 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB SRP54 PF00448.22 OQR98871.1 - 0.085 12.5 1.6 0.14 11.7 0.4 1.8 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain VirC1 PF07015.11 OQR98871.1 - 0.085 12.1 0.2 0.15 11.3 0.2 1.4 1 0 0 1 1 1 0 VirC1 protein NB-ARC PF00931.22 OQR98871.1 - 0.11 11.7 0.5 0.2 10.8 0.5 1.4 1 0 0 1 1 1 0 NB-ARC domain CENP-Q PF13094.6 OQR98871.1 - 0.12 12.6 0.0 0.15 12.2 0.0 1.2 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit NACHT PF05729.12 OQR98871.1 - 0.15 12.0 1.0 0.43 10.5 0.3 1.9 1 1 0 2 2 2 0 NACHT domain AAA_26 PF13500.6 OQR98871.1 - 0.17 11.7 1.1 5.2 6.8 0.5 2.1 2 0 0 2 2 2 0 AAA domain EF-hand_7 PF13499.6 OQR98872.1 - 4.9e-38 129.4 11.3 4.7e-08 33.4 0.0 7.1 6 1 1 7 7 7 7 EF-hand domain pair EF-hand_1 PF00036.32 OQR98872.1 - 2.4e-33 111.2 15.6 0.00031 20.1 0.0 10.0 10 0 0 10 10 10 7 EF hand EF-hand_6 PF13405.6 OQR98872.1 - 1.3e-32 108.9 26.9 0.001 18.8 0.1 10.8 11 0 0 11 11 10 9 EF-hand domain EF-hand_8 PF13833.6 OQR98872.1 - 4.3e-26 90.5 17.3 0.00019 21.2 0.1 8.8 7 2 1 8 8 8 7 EF-hand domain pair EF-hand_5 PF13202.6 OQR98872.1 - 9.8e-26 88.1 15.4 0.00026 20.3 0.0 8.5 8 0 0 8 8 8 6 EF hand Dzip-like_N PF13815.6 OQR98872.1 - 0.00029 20.8 0.2 0.00029 20.8 0.2 3.0 3 1 0 3 3 2 1 Iguana/Dzip1-like DAZ-interacting protein N-terminal SPARC_Ca_bdg PF10591.9 OQR98872.1 - 0.004 17.4 12.7 1.9 8.8 0.1 6.4 4 1 1 5 5 5 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_9 PF14658.6 OQR98872.1 - 0.0047 17.2 0.0 2.9 8.3 0.0 4.7 6 1 1 7 7 7 1 EF-hand domain EF-hand_10 PF14788.6 OQR98872.1 - 0.091 12.6 0.8 37 4.3 0.1 3.9 3 0 0 3 3 3 0 EF hand DUF2555 PF10742.9 OQR98872.1 - 0.11 12.3 0.2 7.4 6.5 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2555) IQ PF00612.27 OQR98872.1 - 0.88 9.5 7.3 6 6.9 0.2 3.1 3 0 0 3 3 3 0 IQ calmodulin-binding motif EF-hand_14 PF17959.1 OQR98872.1 - 3.6 8.0 10.8 5.1 7.5 0.0 5.3 7 0 0 7 7 6 0 EF-hand domain Acyl-CoA_dh_1 PF00441.24 OQR98873.1 - 2.2e-50 170.8 3.2 4.3e-50 169.8 3.2 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 OQR98873.1 - 8.8e-26 90.0 0.2 1.9e-25 88.9 0.2 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 OQR98873.1 - 1.5e-22 80.4 0.1 4e-22 79.0 0.1 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 OQR98873.1 - 1.5e-18 67.3 0.6 2.4e-18 66.7 0.6 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.8 OQR98873.1 - 5.5e-05 23.0 0.3 0.00025 20.8 0.3 1.9 1 1 0 1 1 1 1 4-hydroxyphenylacetate 3-hydroxylase N terminal Acyl-CoA_dh_1 PF00441.24 OQR98874.1 - 6.7e-05 23.1 0.0 8.5e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Trypan_PARP PF05887.11 OQR98875.1 - 4.9 7.1 19.0 12 5.9 19.0 1.8 1 1 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Fe-ADH PF00465.19 OQR98876.1 - 4.2e-56 190.3 0.3 5.2e-56 190.0 0.3 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.6 OQR98876.1 - 1.5e-09 37.9 0.7 0.00024 20.9 0.0 2.2 2 0 0 2 2 2 2 Iron-containing alcohol dehydrogenase DUF2007 PF09413.10 OQR98876.1 - 0.035 14.3 0.0 0.25 11.5 0.0 2.4 2 0 0 2 2 2 0 Putative prokaryotic signal transducing protein DEAD PF00270.29 OQR98877.1 - 1.7e-36 125.7 0.1 3.3e-36 124.7 0.1 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OQR98877.1 - 3.8e-25 88.4 0.2 6.9e-24 84.3 0.2 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Acyl-CoA_dh_M PF02770.19 OQR98877.1 - 1.9e-10 40.8 0.7 4.6e-10 39.6 0.2 1.9 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain ResIII PF04851.15 OQR98877.1 - 2.3e-06 27.7 0.0 4.5e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 OQR98877.1 - 0.00024 20.5 0.0 0.00047 19.6 0.0 1.5 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit Acyl-CoA_dh_1 PF00441.24 OQR98878.1 - 3.3e-09 37.1 0.2 6.9e-08 32.8 0.2 2.0 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_1 PF00441.24 OQR98879.1 - 1.2e-47 161.8 1.9 1.2e-47 161.8 1.9 1.9 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 OQR98879.1 - 9.2e-24 83.5 0.4 2.2e-23 82.3 0.4 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 OQR98879.1 - 1.1e-22 80.8 0.0 3.3e-22 79.3 0.0 1.8 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 OQR98879.1 - 8.4e-21 74.6 0.5 2.1e-20 73.4 0.5 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.8 OQR98879.1 - 0.00021 21.0 0.2 0.0011 18.7 0.2 2.1 1 1 0 1 1 1 1 4-hydroxyphenylacetate 3-hydroxylase N terminal TIP120 PF08623.10 OQR98880.1 - 7.9e-10 38.8 0.2 0.019 14.7 0.0 3.5 3 0 0 3 3 3 3 TATA-binding protein interacting (TIP20) HEAT PF02985.22 OQR98880.1 - 1.4e-08 34.3 0.3 3.8 8.0 0.1 7.0 6 0 0 6 6 6 1 HEAT repeat HEAT_2 PF13646.6 OQR98880.1 - 0.00083 19.7 0.0 2.1 8.8 0.0 4.3 4 0 0 4 4 4 1 HEAT repeats Cnd1 PF12717.7 OQR98880.1 - 0.0011 19.1 0.3 1.3 9.0 0.0 3.2 2 1 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 DUF4042 PF13251.6 OQR98880.1 - 0.006 16.3 0.3 6.8 6.4 0.2 3.5 2 1 0 2 2 2 2 Domain of unknown function (DUF4042) Chordopox_A30L PF06015.12 OQR98880.1 - 0.11 12.4 0.3 0.4 10.6 0.1 2.2 2 0 0 2 2 2 0 Chordopoxvirus A30L protein RIH_assoc PF08454.11 OQR98881.1 - 4.9e-09 36.0 1.3 2.1e-08 33.9 1.3 2.1 1 1 0 1 1 1 1 RyR and IP3R Homology associated Ion_trans PF00520.31 OQR98881.1 - 2.5e-07 30.2 2.6 2.5e-07 30.2 2.6 2.8 2 2 1 3 3 3 1 Ion transport protein LuxT_C PF18285.1 OQR98881.1 - 0.014 15.9 0.1 0.11 13.1 0.1 2.6 1 0 0 1 1 1 0 Tetracycline repressor LuxT C-terminal domain CxC4 PF18717.1 OQR98881.1 - 0.11 12.4 0.2 0.6 9.9 0.1 2.1 2 0 0 2 2 2 0 CxC4 like cysteine cluster associated with KDZ transposases CPP1-like PF11833.8 OQR98881.1 - 1.9 8.1 7.4 0.23 11.1 0.1 3.0 4 0 0 4 4 4 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like MatE PF01554.18 OQR98908.1 - 0.023 14.3 0.0 0.036 13.7 0.0 1.3 1 0 0 1 1 1 0 MatE LicD PF04991.13 OQR98908.1 - 0.055 13.6 0.0 0.12 12.4 0.0 1.6 1 0 0 1 1 1 0 LicD family FYVE PF01363.21 OQR98908.1 - 0.14 12.3 24.8 0.038 14.1 21.0 2.1 2 0 0 2 2 2 0 FYVE zinc finger Aa_trans PF01490.18 OQR98909.1 - 1.3e-40 139.4 28.7 1.6e-40 139.1 28.7 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Tetraspanin PF00335.20 OQR98909.1 - 0.015 15.0 1.0 0.015 15.0 1.0 3.5 3 2 0 3 3 3 0 Tetraspanin family ABC_membrane PF00664.23 OQR98910.1 - 3.9e-57 194.0 37.8 6.4e-33 114.6 13.6 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 OQR98910.1 - 3.9e-43 147.2 0.1 2.3e-28 99.4 0.0 2.8 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 OQR98910.1 - 3.1e-12 46.4 3.4 0.0028 17.1 0.9 4.2 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain Dynamin_N PF00350.23 OQR98910.1 - 2.8e-06 27.5 2.7 0.00051 20.1 0.1 2.8 2 1 0 2 2 2 2 Dynamin family MMR_HSR1 PF01926.23 OQR98910.1 - 4.9e-06 26.6 0.2 0.075 13.1 0.0 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_29 PF13555.6 OQR98910.1 - 2.4e-05 24.0 0.3 0.34 10.7 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_21 PF13304.6 OQR98910.1 - 4.2e-05 23.5 3.8 0.96 9.2 0.2 4.1 2 2 2 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system Zeta_toxin PF06414.12 OQR98910.1 - 0.00051 19.4 0.1 0.017 14.4 0.0 2.5 2 0 0 2 2 2 1 Zeta toxin FtsK_SpoIIIE PF01580.18 OQR98910.1 - 0.00051 19.5 0.2 1.1 8.6 0.0 2.3 2 0 0 2 2 2 2 FtsK/SpoIIIE family AAA_15 PF13175.6 OQR98910.1 - 0.00058 19.7 0.2 0.94 9.1 0.0 2.4 2 0 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 OQR98910.1 - 0.00071 19.5 0.3 1.6 8.6 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_23 PF13476.6 OQR98910.1 - 0.0044 17.5 2.1 0.92 10.0 0.0 2.8 3 0 0 3 3 2 1 AAA domain AAA_24 PF13479.6 OQR98910.1 - 0.0055 16.4 0.0 0.013 15.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_7 PF12775.7 OQR98910.1 - 0.006 16.1 0.2 1.1 8.8 0.0 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region DUF815 PF05673.13 OQR98910.1 - 0.0061 15.7 0.0 2.7 7.1 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF815) AAA_16 PF13191.6 OQR98910.1 - 0.011 16.1 0.1 2.1 8.7 0.0 2.6 2 0 0 2 2 2 0 AAA ATPase domain DUF87 PF01935.17 OQR98910.1 - 0.028 14.5 0.1 0.073 13.2 0.1 1.6 1 0 0 1 1 1 0 Helicase HerA, central domain AAA_18 PF13238.6 OQR98910.1 - 0.03 14.9 0.5 20 5.8 0.1 3.5 3 0 0 3 3 3 0 AAA domain AAA_22 PF13401.6 OQR98910.1 - 0.032 14.5 0.4 2.1 8.6 0.0 2.7 2 1 0 2 2 2 0 AAA domain T2SSE PF00437.20 OQR98910.1 - 0.073 12.1 0.1 5 6.1 0.0 2.4 2 0 0 2 2 2 0 Type II/IV secretion system protein Roc PF08477.13 OQR98910.1 - 0.14 12.4 0.2 34 4.7 0.1 2.8 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase K-box PF01486.17 OQR98910.1 - 0.14 12.3 0.3 0.37 11.0 0.3 1.6 1 0 0 1 1 1 0 K-box region AAA_33 PF13671.6 OQR98910.1 - 0.16 12.2 0.1 12 6.1 0.0 2.6 2 0 0 2 2 2 0 AAA domain Ank_5 PF13857.6 OQR98911.1 - 6.1e-27 93.3 17.0 0.0047 17.2 0.0 9.2 2 1 7 9 9 9 8 Ankyrin repeats (many copies) Ank_2 PF12796.7 OQR98911.1 - 1.2e-24 86.7 7.6 3.2e-09 37.3 0.1 4.6 1 1 3 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQR98911.1 - 1.7e-19 69.9 14.5 0.00013 22.5 0.0 6.8 2 2 5 8 8 8 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQR98911.1 - 6.1e-15 53.8 10.5 5 8.0 0.0 10.1 6 2 4 10 10 10 4 Ankyrin repeat Ank PF00023.30 OQR98911.1 - 0.01 16.3 4.5 1.3e+02 3.3 1.5 6.6 3 1 2 5 5 5 0 Ankyrin repeat VHL_C PF17211.3 OQR98911.1 - 0.012 15.6 0.1 20 5.3 0.0 4.5 7 0 0 7 7 7 0 VHL box domain MFS_1 PF07690.16 OQR98913.1 - 3.7e-31 108.3 35.3 3.7e-31 108.3 35.3 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily OATP PF03137.20 OQR98913.1 - 2.8e-23 82.0 26.7 1e-15 57.1 7.7 4.0 2 2 1 3 3 3 3 Organic Anion Transporter Polypeptide (OATP) family Sugar_tr PF00083.24 OQR98913.1 - 5e-11 42.1 20.2 4.1e-10 39.1 20.2 2.2 1 1 0 1 1 1 1 Sugar (and other) transporter Ricin_B_lectin PF00652.22 OQR98914.1 - 1.2e-21 77.2 3.2 8.4e-16 58.4 0.7 2.5 2 0 0 2 2 2 2 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.6 OQR98914.1 - 1.4e-09 38.5 4.5 0.022 15.5 0.1 4.0 3 2 1 4 4 4 3 Ricin-type beta-trefoil lectin domain-like CDtoxinA PF03498.14 OQR98914.1 - 0.0011 18.6 2.1 0.17 11.4 0.8 2.8 2 1 0 2 2 2 2 Cytolethal distending toxin A/C domain Cys_Met_Meta_PP PF01053.20 OQR98915.1 - 1.5e-35 122.4 0.0 2e-35 122.1 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Gtr1_RagA PF04670.12 OQR98916.1 - 2.4e-99 331.4 0.2 2.9e-99 331.1 0.2 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Arf PF00025.21 OQR98916.1 - 1.1e-09 38.0 0.0 6e-09 35.6 0.0 2.0 1 1 1 2 2 2 1 ADP-ribosylation factor family Roc PF08477.13 OQR98916.1 - 4.2e-09 36.7 0.0 2.5e-08 34.2 0.0 2.2 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 OQR98916.1 - 1.5e-07 31.1 0.0 5.5e-07 29.3 0.0 1.9 2 1 0 2 2 2 1 Ras family MMR_HSR1 PF01926.23 OQR98916.1 - 1e-05 25.6 0.0 2e-05 24.7 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 OQR98916.1 - 0.0095 15.9 0.2 4.5 7.2 0.1 2.4 2 0 0 2 2 2 2 RsgA GTPase SRPRB PF09439.10 OQR98916.1 - 0.03 13.8 0.0 0.046 13.2 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit PduV-EutP PF10662.9 OQR98916.1 - 0.031 14.0 0.1 0.081 12.7 0.1 1.6 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_24 PF13479.6 OQR98916.1 - 0.061 13.0 0.1 0.15 11.8 0.1 1.6 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 OQR98916.1 - 0.063 13.8 0.4 0.17 12.4 0.1 1.8 2 1 0 2 2 2 0 ABC transporter MMR_HSR1_Xtn PF16897.5 OQR98916.1 - 0.1 12.6 0.1 0.38 10.8 0.0 1.9 2 0 0 2 2 2 0 C-terminal region of MMR_HSR1 domain XPG_I PF00867.18 OQR98931.1 - 4.8e-22 78.1 0.0 1e-21 77.1 0.0 1.5 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.17 OQR98931.1 - 3.4e-12 46.7 0.0 7.4e-12 45.6 0.0 1.6 1 1 0 1 1 1 1 XPG N-terminal domain XPG_I_2 PF12813.7 OQR98931.1 - 0.033 13.7 0.0 0.052 13.0 0.0 1.3 1 0 0 1 1 1 0 XPG domain containing HHH_5 PF14520.6 OQR98931.1 - 0.054 14.1 0.0 0.15 12.7 0.0 1.7 1 0 0 1 1 1 0 Helix-hairpin-helix domain CBAH PF02275.18 OQR98932.1 - 3.7e-103 345.5 0.0 1.9e-33 116.5 0.0 6.2 3 3 0 3 3 3 3 Linear amide C-N hydrolases, choloylglycine hydrolase family KTSC PF13619.6 OQR98932.1 - 0.0062 16.3 0.0 3.1 7.7 0.0 3.3 3 0 0 3 3 3 1 KTSC domain DUF3100 PF11299.8 OQR98932.1 - 0.095 12.1 0.1 0.095 12.1 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3100) RT_RNaseH PF17917.1 OQR98932.1 - 0.099 12.9 0.3 3 8.2 0.0 3.0 3 0 0 3 3 3 0 RNase H-like domain found in reverse transcriptase Metallophos PF00149.28 OQR98934.1 - 3.6e-13 50.5 2.0 5.2e-06 27.1 0.2 2.7 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase EphA2_TM PF14575.6 OQR98934.1 - 0.0011 19.7 0.5 3.5 8.6 0.0 3.2 3 0 0 3 3 3 2 Ephrin type-A receptor 2 transmembrane domain Wzz PF02706.15 OQR98934.1 - 0.033 14.5 0.6 1.2 9.5 0.1 2.7 2 0 0 2 2 2 0 Chain length determinant protein DUF4307 PF14155.6 OQR98934.1 - 0.095 12.5 4.3 2.6 7.9 0.1 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4307) DUF2749 PF10907.8 OQR98934.1 - 0.44 10.7 8.9 4.6 7.5 0.9 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2749) DUF4330 PF14221.6 OQR98934.1 - 1.7 8.8 4.3 16 5.7 0.2 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4330) ADH_zinc_N_2 PF13602.6 OQR98935.1 - 2.1e-13 51.5 0.0 2.6e-13 51.2 0.0 1.1 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 OQR98935.1 - 3.1e-11 43.4 0.1 4.2e-11 43.0 0.1 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Dynein_light PF01221.18 OQR98936.1 - 1.7e-16 60.3 0.3 1.2e-07 31.9 0.0 2.8 2 0 0 2 2 2 2 Dynein light chain type 1 PLAC8 PF04749.17 OQR98936.1 - 3.7e-16 59.9 11.5 3.7e-16 59.9 11.5 2.3 2 1 0 2 2 2 1 PLAC8 family PLAC8 PF04749.17 OQR98937.1 - 1e-17 64.9 15.5 1.4e-17 64.5 15.5 1.1 1 0 0 1 1 1 1 PLAC8 family MINDY_DUB PF04424.13 OQR98938.1 - 2.1e-28 98.7 0.1 4.1e-28 97.7 0.1 1.5 1 0 0 1 1 1 1 MINDY deubiquitinase Ricin_B_lectin PF00652.22 OQR98939.1 - 7.3e-05 23.0 0.3 9.3e-05 22.7 0.3 1.2 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain CDtoxinA PF03498.14 OQR98939.1 - 0.012 15.2 0.2 0.015 14.9 0.2 1.1 1 0 0 1 1 1 0 Cytolethal distending toxin A/C domain IFRD PF05004.13 OQR98940.1 - 4.7e-19 68.6 0.1 5.9e-19 68.3 0.1 1.1 1 0 0 1 1 1 1 Interferon-related developmental regulator (IFRD) UME PF08064.13 OQR98940.1 - 0.079 12.9 0.2 10 6.1 0.0 2.3 2 0 0 2 2 2 0 UME (NUC010) domain COMM_domain PF07258.14 OQR98941.1 - 2.1e-13 50.2 0.2 8e-13 48.3 0.0 2.2 2 0 0 2 2 2 1 COMM domain IFRD PF05004.13 OQR98941.1 - 8.3e-13 48.1 0.0 1.6e-12 47.2 0.0 1.4 1 0 0 1 1 1 1 Interferon-related developmental regulator (IFRD) HEAT_2 PF13646.6 OQR98941.1 - 0.11 12.9 2.0 1.4 9.4 0.0 3.1 4 1 0 4 4 4 0 HEAT repeats WWE PF02825.20 OQR98942.1 - 1.7e-07 31.7 1.3 6.2e-07 29.9 1.3 2.0 1 0 0 1 1 1 1 WWE domain WGR PF05406.15 OQR98942.1 - 8.2e-05 22.6 0.1 8.2e-05 22.6 0.1 1.9 2 0 0 2 2 2 1 WGR domain LicD PF04991.13 OQR98943.1 - 9.5e-18 65.2 0.2 6.7e-09 36.2 0.2 2.5 2 1 0 2 2 2 2 LicD family MAT1-1-2 PF17043.5 OQR98943.1 - 0.17 11.7 0.1 0.34 10.7 0.0 1.6 2 0 0 2 2 2 0 Mating type protein 1-1-2 of unknown function Mannosyl_trans3 PF11051.8 OQR98944.1 - 2.1e-25 89.6 0.0 2.9e-25 89.2 0.0 1.2 1 0 0 1 1 1 1 Mannosyltransferase putative adh_short PF00106.25 OQR98945.1 - 8.6e-52 175.4 0.0 1.9e-51 174.3 0.0 1.6 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OQR98945.1 - 1.5e-31 109.8 0.1 3.6e-31 108.5 0.1 1.6 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OQR98945.1 - 1.2e-12 48.1 0.1 3.9e-12 46.5 0.1 1.8 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 OQR98945.1 - 0.049 13.1 0.0 0.12 11.8 0.0 1.7 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family N6_N4_Mtase PF01555.18 OQR98945.1 - 0.26 10.9 4.2 0.24 11.1 0.5 2.4 2 0 0 2 2 2 0 DNA methylase Sec1 PF00995.23 OQR98946.1 - 1.1e-71 242.8 0.0 1.3e-71 242.6 0.0 1.0 1 0 0 1 1 1 1 Sec1 family Peptidase_M14 PF00246.24 OQR98947.1 - 2e-41 142.7 0.0 3.4e-41 141.9 0.0 1.4 2 0 0 2 2 2 1 Zinc carboxypeptidase DUF2817 PF10994.8 OQR98947.1 - 0.2 11.0 0.0 0.36 10.2 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2817) 2OG-FeII_Oxy_3 PF13640.6 OQR98948.1 - 6.4e-14 52.6 0.2 1.6e-13 51.3 0.1 1.8 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily Peptidase_C1_2 PF03051.15 OQR98949.1 - 3.8e-79 266.5 0.1 4.2e-79 266.4 0.1 1.0 1 0 0 1 1 1 1 Peptidase C1-like family Peptidase_C1 PF00112.23 OQR98949.1 - 0.0003 20.9 0.7 0.00054 20.1 0.7 1.4 1 0 0 1 1 1 1 Papain family cysteine protease Ricin_B_lectin PF00652.22 OQR98950.1 - 7.9e-40 136.0 36.6 5.3e-15 55.8 9.8 3.1 1 1 2 3 3 3 3 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.6 OQR98950.1 - 1.1e-08 35.7 24.4 0.00047 20.8 2.8 4.4 3 2 2 5 5 5 4 Ricin-type beta-trefoil lectin domain-like CDtoxinA PF03498.14 OQR98950.1 - 0.00016 21.3 6.1 0.07 12.7 0.3 3.2 1 1 2 3 3 3 2 Cytolethal distending toxin A/C domain DUF1329 PF07044.11 OQR98950.1 - 0.022 14.1 4.2 0.065 12.5 0.1 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1329) PQQ PF01011.21 OQR98950.1 - 0.078 12.9 1.5 0.33 10.9 0.0 2.9 3 0 0 3 3 3 0 PQQ enzyme repeat PseudoU_synth_2 PF00849.22 OQR99113.1 - 1.1e-30 106.8 0.1 2.5e-30 105.7 0.1 1.6 1 1 0 1 1 1 1 RNA pseudouridylate synthase DUF5132 PF17195.4 OQR99113.1 - 0.17 12.0 0.0 0.31 11.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF5132) Aldo_ket_red PF00248.21 OQR99113.1 - 0.2 10.8 0.0 0.28 10.3 0.0 1.2 1 0 0 1 1 1 0 Aldo/keto reductase family Glycos_transf_N PF04413.16 OQR99114.1 - 2.4e-49 167.4 0.2 4.3e-49 166.6 0.2 1.4 1 0 0 1 1 1 1 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) SET PF00856.28 OQR99114.1 - 8.4e-22 78.3 0.3 4.6e-10 40.1 0.0 3.5 2 1 0 2 2 2 2 SET domain Toxin_25 PF08095.11 OQR99114.1 - 0.036 14.0 0.2 0.12 12.3 0.2 2.0 1 0 0 1 1 1 0 Hefutoxin family Acyl-CoA_dh_N PF02771.16 OQR99115.1 - 0.07 13.8 0.0 0.12 13.1 0.0 1.3 1 0 0 1 1 1 0 Acyl-CoA dehydrogenase, N-terminal domain ICL PF00463.21 OQR99116.1 - 2.1e-204 679.9 0.6 4.9e-204 678.7 0.6 1.5 1 1 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.6 OQR99116.1 - 2e-11 43.8 0.2 1.1e-10 41.4 0.0 2.1 2 0 0 2 2 2 1 Phosphoenolpyruvate phosphomutase KCNQ_channel PF03520.14 OQR99116.1 - 0.052 13.4 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 KCNQ voltage-gated potassium channel tRNA-synt_2e PF02091.15 OQR99116.1 - 0.074 12.3 0.1 0.12 11.6 0.1 1.3 1 0 0 1 1 1 0 Glycyl-tRNA synthetase alpha subunit Kinesin PF00225.23 OQR99117.1 - 5e-102 341.2 0.1 5.7e-102 341.0 0.1 1.0 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 OQR99117.1 - 2.8e-31 108.5 0.1 4.5e-31 107.8 0.1 1.3 1 0 0 1 1 1 1 Microtubule binding AAA_22 PF13401.6 OQR99117.1 - 0.0026 18.1 0.1 0.0071 16.6 0.0 1.9 2 1 0 2 2 2 1 AAA domain Bac_DnaA PF00308.18 OQR99117.1 - 0.022 14.6 0.0 0.043 13.6 0.0 1.5 1 0 0 1 1 1 0 Bacterial dnaA protein AAA_16 PF13191.6 OQR99117.1 - 0.035 14.5 0.0 0.057 13.8 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain SP2 PF03014.14 OQR99117.1 - 0.036 12.5 0.0 0.048 12.1 0.0 1.1 1 0 0 1 1 1 0 Structural protein 2 PIF1 PF05970.14 OQR99117.1 - 0.036 13.2 0.1 0.062 12.5 0.1 1.3 1 0 0 1 1 1 0 PIF1-like helicase AAA_7 PF12775.7 OQR99117.1 - 0.058 12.9 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region Pro_CA PF00484.19 OQR99118.1 - 6.1e-50 169.5 0.1 1.1e-49 168.8 0.1 1.4 1 0 0 1 1 1 1 Carbonic anhydrase RRM_1 PF00076.22 OQR99118.1 - 1.3e-32 111.4 0.2 1.9e-15 56.5 0.1 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 OQR99118.1 - 2.5e-14 53.2 0.0 6.5e-06 26.2 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif Nup35_RRM_2 PF14605.6 OQR99118.1 - 6.9e-05 22.8 0.1 0.068 13.2 0.0 2.4 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif OB_RNB PF08206.11 OQR99118.1 - 0.079 12.6 0.2 17 5.2 0.0 2.6 2 0 0 2 2 2 0 Ribonuclease B OB domain RVT_3 PF13456.6 OQR99119.1 - 1.1e-12 47.9 0.0 1.3e-12 47.6 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase-like Ank_2 PF12796.7 OQR99120.1 - 2.7e-46 156.0 6.7 4.4e-16 59.2 0.1 6.0 1 1 1 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQR99120.1 - 1.1e-39 134.3 6.8 6.7e-10 39.3 0.0 7.8 3 1 6 9 9 9 9 Ankyrin repeats (many copies) RTP1_C1 PF10363.9 OQR99120.1 - 2.9e-30 104.7 1.6 2.9e-29 101.5 0.3 3.2 2 1 1 3 3 3 1 Required for nuclear transport of RNA pol II C-terminus 1 Ank_5 PF13857.6 OQR99120.1 - 8.9e-30 102.4 7.6 5.8e-05 23.3 0.1 7.6 3 1 3 7 7 7 7 Ankyrin repeats (many copies) Ank PF00023.30 OQR99120.1 - 1.7e-28 97.8 22.5 1.2e-06 28.7 0.1 11.5 10 1 1 11 11 11 6 Ankyrin repeat Ank_3 PF13606.6 OQR99120.1 - 5.7e-25 84.6 11.4 0.0046 17.3 0.0 11.7 11 0 0 11 11 11 4 Ankyrin repeat RTP1_C2 PF10304.9 OQR99120.1 - 1.4e-06 27.9 0.0 4.9e-06 26.1 0.0 1.9 1 0 0 1 1 1 1 Required for nuclear transport of RNA pol II C-terminus 2 F-box PF00646.33 OQR99120.1 - 0.00015 21.5 0.7 0.0004 20.2 0.0 2.1 2 0 0 2 2 2 1 F-box domain Telomere_reg-2 PF10193.9 OQR99120.1 - 0.00093 19.6 3.0 0.089 13.2 0.2 3.5 3 0 0 3 3 2 1 Telomere length regulation protein F-box-like PF12937.7 OQR99120.1 - 0.07 13.0 0.8 0.24 11.3 0.0 2.3 2 0 0 2 2 2 0 F-box-like HEAT_2 PF13646.6 OQR99120.1 - 0.17 12.3 2.8 1.4 9.4 0.1 4.0 5 0 0 5 5 5 0 HEAT repeats UME PF08064.13 OQR99120.1 - 0.18 11.7 0.7 3.2 7.7 0.1 3.4 3 0 0 3 3 3 0 UME (NUC010) domain PX PF00787.24 OQR99121.1 - 3.2e-07 30.3 0.1 1.2e-06 28.5 0.1 1.9 1 0 0 1 1 1 1 PX domain DUF3140 PF11338.8 OQR99121.1 - 0.2 12.1 2.3 0.58 10.6 0.7 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3140) ACPS PF01648.20 OQR99122.1 - 1.7e-15 57.1 0.0 3.4e-15 56.1 0.0 1.5 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily GNAT_acetyltran PF12746.7 OQR99122.1 - 0.045 13.3 0.0 0.074 12.6 0.0 1.3 1 0 0 1 1 1 0 GNAT acetyltransferase Inhibitor_I78 PF11720.8 OQR99122.1 - 0.048 13.7 0.0 0.083 13.0 0.0 1.4 1 0 0 1 1 1 0 Peptidase inhibitor I78 family UTRA PF07702.13 OQR99122.1 - 0.18 11.7 0.0 0.3 10.9 0.0 1.3 1 0 0 1 1 1 0 UTRA domain Nuf2 PF03800.14 OQR99123.1 - 2.3e-35 121.7 1.0 2.3e-35 121.7 1.0 2.7 3 1 0 3 3 3 1 Nuf2 family DHR10 PF18595.1 OQR99123.1 - 7.9e-18 64.6 21.2 7.9e-18 64.6 21.2 4.2 2 2 2 4 4 4 1 Designed helical repeat protein 10 domain Spidroin_N PF16763.5 OQR99123.1 - 0.017 15.1 4.5 0.055 13.5 4.5 2.0 1 0 0 1 1 1 0 Major ampullate spidroin 1, spider silk protein 1, N-term PHO4 PF01384.20 OQR99158.1 - 1.1e-23 83.8 7.2 1.3e-23 83.6 7.2 1.0 1 0 0 1 1 1 1 Phosphate transporter family DUF4457 PF14652.6 OQR99159.1 - 1.3e-144 481.5 0.0 8.2e-96 321.1 0.0 4.5 4 1 1 5 5 5 4 Domain of unknown function (DUF4457) Sad1_UNC PF07738.13 OQR99159.1 - 0.00012 22.1 0.0 12 5.9 0.0 4.9 5 0 0 5 5 5 2 Sad1 / UNC-like C-terminal DUF2222 PF09984.9 OQR99159.1 - 0.061 13.2 1.8 0.15 11.9 0.8 2.1 2 0 0 2 2 2 0 Uncharacterised signal transduction histidine kinase domain (DUF2222) PEARLI-4 PF05278.12 OQR99159.1 - 6.2 6.3 16.7 1 8.9 6.0 2.4 2 0 0 2 2 2 0 Arabidopsis phospholipase-like protein (PEARLI 4) UCH PF00443.29 OQR99160.1 - 7.4e-21 74.8 0.0 1.2e-20 74.2 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 OQR99160.1 - 3.5e-10 40.0 5.2 5.4e-09 36.1 5.2 2.3 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase PDZ PF00595.24 OQR99160.1 - 7.8e-06 26.2 0.0 1.6e-05 25.2 0.0 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 OQR99160.1 - 0.00019 21.2 0.0 0.00046 20.0 0.0 1.7 1 0 0 1 1 1 1 PDZ domain zf-RanBP PF00641.18 OQR99160.1 - 0.0055 16.0 2.1 0.017 14.4 2.1 1.9 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others PDZ_2 PF13180.6 OQR99160.1 - 0.085 13.2 0.0 0.18 12.1 0.0 1.5 1 0 0 1 1 1 0 PDZ domain PHO4 PF01384.20 OQR99161.1 - 2.9e-66 223.9 23.0 3.8e-66 223.5 23.0 1.1 1 0 0 1 1 1 1 Phosphate transporter family JmjC PF02373.22 OQR99162.1 - 4e-17 62.7 0.4 1.7e-16 60.7 0.0 2.2 2 0 0 2 2 2 1 JmjC domain, hydroxylase Cupin_8 PF13621.6 OQR99162.1 - 3.2e-14 53.3 0.2 7.9e-14 52.0 0.2 1.6 1 0 0 1 1 1 1 Cupin-like domain F-box-like PF12937.7 OQR99162.1 - 0.00045 20.1 1.7 0.0012 18.7 0.2 2.6 2 0 0 2 2 2 1 F-box-like APH PF01636.23 OQR99162.1 - 0.00047 20.2 0.6 0.24 11.3 0.1 2.4 2 0 0 2 2 2 2 Phosphotransferase enzyme family Cupin_4 PF08007.12 OQR99162.1 - 0.012 15.1 0.8 0.03 13.8 0.0 2.1 3 0 0 3 3 3 0 Cupin superfamily protein F-box PF00646.33 OQR99162.1 - 0.037 13.9 0.0 0.12 12.3 0.0 1.9 1 0 0 1 1 1 0 F-box domain CRAL_TRIO PF00650.20 OQR99163.1 - 1.9e-29 102.4 0.2 3e-29 101.8 0.2 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain LRR_8 PF13855.6 OQR99164.1 - 8.7e-08 31.8 16.4 4.7e-06 26.3 0.9 4.5 4 1 1 5 5 5 2 Leucine rich repeat Notch PF00066.17 OQR99164.1 - 1.1e-05 25.8 10.5 1.1e-05 25.8 10.5 1.8 2 0 0 2 2 2 1 LNR domain LRR_4 PF12799.7 OQR99164.1 - 0.0001 22.6 16.5 0.012 16.0 0.6 5.7 6 1 1 7 7 7 3 Leucine Rich repeats (2 copies) CSRNP_N PF16019.5 OQR99165.1 - 0.0006 19.8 0.0 0.00072 19.5 0.0 1.1 1 0 0 1 1 1 1 Cysteine/serine-rich nuclear protein N-terminus Prefoldin PF02996.17 OQR99166.1 - 7.8e-17 61.3 2.1 9.8e-17 61.0 2.1 1.1 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin_2 PF01920.20 OQR99166.1 - 0.035 14.1 3.5 1.1 9.3 0.4 2.3 2 0 0 2 2 2 0 Prefoldin subunit GTP_EFTU PF00009.27 OQR99167.1 - 4.2e-55 186.3 0.0 4.8e-55 186.1 0.0 1.1 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 OQR99167.1 - 0.019 15.0 0.0 0.05 13.7 0.0 1.7 1 1 0 1 1 1 0 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 OQR99167.1 - 0.11 12.3 0.1 0.49 10.3 0.0 2.0 2 0 0 2 2 2 0 RsgA GTPase PH PF00169.29 OQR99168.1 - 1.4e-07 32.0 0.5 5.6e-07 30.0 0.5 1.9 1 1 0 1 1 1 1 PH domain PH_8 PF15409.6 OQR99168.1 - 0.0004 20.6 0.5 0.21 11.9 0.7 2.5 2 1 0 2 2 2 2 Pleckstrin homology domain PH_11 PF15413.6 OQR99168.1 - 0.0036 17.7 0.7 0.0065 16.9 0.7 1.7 1 1 0 1 1 1 1 Pleckstrin homology domain PH_9 PF15410.6 OQR99168.1 - 0.041 14.2 0.1 0.078 13.3 0.1 1.5 1 1 0 1 1 1 0 Pleckstrin homology domain YjcQ PF09639.10 OQR99169.1 - 0.082 13.1 0.0 0.18 12.0 0.0 1.6 1 1 0 1 1 1 0 YjcQ protein RPW8 PF05659.11 OQR99170.1 - 0.055 13.1 9.1 0.074 12.7 3.5 2.6 1 1 1 2 2 2 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 EF-hand_7 PF13499.6 OQR99170.1 - 0.11 13.0 2.1 3.4 8.2 0.0 3.7 3 0 0 3 3 3 0 EF-hand domain pair Syntaxin-6_N PF09177.11 OQR99170.1 - 0.16 12.5 10.9 0.19 12.3 6.9 3.3 1 1 1 2 2 2 0 Syntaxin 6, N-terminal Med9 PF07544.13 OQR99170.1 - 0.28 11.3 11.3 0.11 12.6 6.3 2.8 1 1 1 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 BLOC1_2 PF10046.9 OQR99170.1 - 2.2 8.6 13.4 0.69 10.3 3.1 3.1 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 NPV_P10 PF05531.12 OQR99170.1 - 5.1 7.6 9.8 0.36 11.3 1.8 3.1 3 1 1 4 4 4 0 Nucleopolyhedrovirus P10 protein DUF489 PF04356.12 OQR99170.1 - 6 6.8 9.2 0.67 9.9 2.3 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF489) CorA PF01544.18 OQR99170.1 - 7.5 5.8 11.8 20 4.3 11.8 1.8 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein Patched PF02460.18 OQR99171.1 - 6.6e-80 269.3 15.6 3.6e-79 266.8 15.7 1.8 1 1 0 1 1 1 1 Patched family Sterol-sensing PF12349.8 OQR99171.1 - 3.8e-44 150.2 3.5 3.8e-44 150.2 3.5 3.2 2 1 1 3 3 3 2 Sterol-sensing domain of SREBP cleavage-activation MMPL PF03176.15 OQR99171.1 - 2.2e-06 26.8 8.8 2.2e-06 26.8 8.8 2.4 2 0 0 2 2 2 1 MMPL family ADIP PF11559.8 OQR99173.1 - 2.1e-11 44.1 13.9 2.1e-11 44.1 13.9 3.9 3 1 1 4 4 4 2 Afadin- and alpha -actinin-Binding Aida_N PF08910.10 OQR99173.1 - 0.026 14.9 0.9 0.026 14.9 0.9 3.4 2 1 1 3 3 3 0 Aida N-terminus DUF4407 PF14362.6 OQR99173.1 - 0.04 13.3 20.7 0.048 13.0 8.3 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4407) Baculo_PEP_C PF04513.12 OQR99173.1 - 4.1 7.4 12.6 0.31 11.1 1.3 3.1 2 2 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus PH PF00169.29 OQR99174.1 - 1.4e-06 28.8 0.3 2.4e-06 28.0 0.3 1.3 1 0 0 1 1 1 1 PH domain PH_15 PF17339.2 OQR99174.1 - 0.0088 15.9 0.0 0.02 14.8 0.0 1.5 1 0 0 1 1 1 1 PH domain PX PF00787.24 OQR99175.1 - 8.8e-07 28.9 0.1 2e-06 27.7 0.1 1.6 1 0 0 1 1 1 1 PX domain 4HBT_2 PF13279.6 OQR99176.1 - 7.3e-20 71.7 0.0 8.6e-20 71.5 0.0 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl-ACP_TE PF01643.17 OQR99176.1 - 0.021 14.1 0.1 0.034 13.4 0.1 1.2 1 0 0 1 1 1 0 Acyl-ACP thioesterase 4HBT PF03061.22 OQR99176.1 - 0.06 13.7 0.0 0.1 12.9 0.0 1.3 1 0 0 1 1 1 0 Thioesterase superfamily TMEM126 PF07114.11 OQR99177.1 - 0.024 14.0 1.2 0.086 12.2 1.0 2.0 2 0 0 2 2 2 0 Transmembrane protein 126 Big_3_3 PF13750.6 OQR99178.1 - 0.0028 17.3 0.1 0.011 15.4 0.1 2.0 1 0 0 1 1 1 1 Bacterial Ig-like domain (group 3) Cadherin_3 PF16184.5 OQR99178.1 - 0.0038 17.2 9.3 0.27 11.3 0.1 7.2 8 0 0 8 8 8 1 Cadherin-like Big_9 PF17963.1 OQR99178.1 - 0.004 17.9 0.3 0.026 15.2 0.1 14.0 16 1 0 16 16 16 2 Bacterial Ig domain Cadherin_5 PF17892.1 OQR99178.1 - 0.0072 16.3 5.6 1.6 8.8 0.0 5.0 5 0 0 5 5 5 1 Cadherin-like domain Cadherin_4 PF17803.1 OQR99178.1 - 0.063 13.9 0.1 0.063 13.9 0.1 10.1 12 0 0 12 12 12 0 Bacterial cadherin-like domain WW PF00397.26 OQR99179.1 - 3.4e-28 97.4 41.6 8.7e-09 35.3 0.9 4.7 4 0 0 4 4 4 4 WW domain PQQ PF01011.21 OQR99179.1 - 0.86 9.7 3.2 37 4.5 0.1 3.8 3 1 1 4 4 4 0 PQQ enzyme repeat YL1_C PF08265.11 OQR99179.1 - 5.1 6.9 7.3 1.1 9.1 2.5 2.4 2 0 0 2 2 2 0 YL1 nuclear protein C-terminal domain Glyco_hyd_101C PF17451.2 OQR99179.1 - 5.6 7.3 28.5 2.3 8.5 4.4 4.8 4 1 1 5 5 5 0 Glycosyl hydrolase 101 beta sandwich domain Ank_4 PF13637.6 OQR99180.1 - 3.1e-11 43.6 0.8 8.8e-09 35.7 0.3 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 OQR99180.1 - 1e-07 32.0 0.8 0.00023 21.4 0.1 3.2 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQR99180.1 - 4.1e-07 29.8 1.6 0.04 14.4 0.0 4.2 3 1 0 3 3 3 2 Ankyrin repeat Ank_2 PF12796.7 OQR99180.1 - 6.8e-07 29.8 0.2 1e-05 26.0 0.1 2.3 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 OQR99180.1 - 0.0087 16.5 1.1 0.9 10.1 0.0 3.2 3 0 0 3 3 3 1 Ankyrin repeat AAA_6 PF12774.7 OQR99244.1 - 4.1e-133 443.4 0.0 2.6e-132 440.8 0.0 2.5 2 0 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 OQR99244.1 - 2.2e-117 392.5 11.4 2.2e-117 392.5 11.4 4.0 4 1 0 4 4 4 1 Dynein heavy chain, N-terminal region 2 DHC_N1 PF08385.12 OQR99244.1 - 4.9e-70 236.8 10.4 4.9e-70 236.8 10.4 3.7 3 1 1 4 4 4 1 Dynein heavy chain, N-terminal region 1 AAA_8 PF12780.7 OQR99244.1 - 2.6e-69 233.5 0.2 1.7e-68 230.7 0.0 2.7 2 0 0 2 2 2 1 P-loop containing dynein motor region D4 AAA_7 PF12775.7 OQR99244.1 - 1.7e-42 145.0 0.0 4.3e-33 114.3 0.0 5.0 5 0 0 5 5 4 2 P-loop containing dynein motor region AAA_5 PF07728.14 OQR99244.1 - 2e-29 102.3 0.0 8.5e-14 51.7 0.0 6.2 4 1 0 4 4 4 3 AAA domain (dynein-related subfamily) Dynein_AAA_lid PF17852.1 OQR99244.1 - 3.2e-21 75.8 0.1 3.2e-21 75.8 0.1 3.8 4 0 0 4 4 3 1 Dynein heavy chain AAA lid domain AAA_22 PF13401.6 OQR99244.1 - 7.1e-16 58.7 0.1 0.0016 18.7 0.0 6.4 5 0 0 5 5 5 4 AAA domain AAA PF00004.29 OQR99244.1 - 1.3e-15 58.0 0.0 0.0039 17.6 0.0 5.5 5 0 0 5 5 4 4 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 OQR99244.1 - 1.4e-10 41.9 1.7 1.5 9.2 0.0 7.0 7 0 0 7 7 5 3 AAA ATPase domain AAA_33 PF13671.6 OQR99244.1 - 1e-08 35.5 0.0 0.17 12.0 0.0 5.5 4 0 0 4 4 4 2 AAA domain AAA_18 PF13238.6 OQR99244.1 - 2.3e-07 31.4 0.2 3.1 8.4 0.0 5.7 4 0 0 4 4 4 1 AAA domain Mg_chelatase PF01078.21 OQR99244.1 - 9.3e-06 25.2 3.4 0.26 10.6 0.0 4.3 4 0 0 4 4 3 2 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 OQR99244.1 - 2.7e-05 24.0 0.6 0.57 9.9 0.0 4.7 4 0 0 4 4 4 1 IstB-like ATP binding protein T2SSE PF00437.20 OQR99244.1 - 5.4e-05 22.4 0.0 0.047 12.7 0.0 3.6 3 0 0 3 3 3 1 Type II/IV secretion system protein ABC_tran PF00005.27 OQR99244.1 - 6e-05 23.6 0.1 3.6 8.1 0.0 4.8 4 0 0 4 4 3 1 ABC transporter RsgA_GTPase PF03193.16 OQR99244.1 - 8.8e-05 22.5 0.0 2.8 7.8 0.0 3.9 3 0 0 3 3 3 1 RsgA GTPase AAA_19 PF13245.6 OQR99244.1 - 9.6e-05 22.7 0.2 0.14 12.5 0.0 4.2 4 0 0 4 4 4 1 AAA domain AAA_25 PF13481.6 OQR99244.1 - 0.00021 20.9 1.9 0.095 12.3 0.0 4.7 4 0 0 4 4 4 1 AAA domain Sigma54_activ_2 PF14532.6 OQR99244.1 - 0.0003 20.9 0.5 2.6 8.2 0.2 4.8 4 0 0 4 4 4 1 Sigma-54 interaction domain RNA_helicase PF00910.22 OQR99244.1 - 0.00034 21.0 0.1 5.3 7.5 0.0 4.8 4 0 0 4 4 4 0 RNA helicase AAA_24 PF13479.6 OQR99244.1 - 0.00039 20.2 0.1 21 4.8 0.0 4.9 4 0 0 4 4 4 0 AAA domain NACHT PF05729.12 OQR99244.1 - 0.00046 20.1 0.7 8.1 6.3 0.0 4.7 4 0 0 4 4 3 0 NACHT domain RuvB_N PF05496.12 OQR99244.1 - 0.00073 19.3 0.0 1.2 8.9 0.0 3.6 3 0 0 3 3 3 1 Holliday junction DNA helicase RuvB P-loop domain AAA_30 PF13604.6 OQR99244.1 - 0.00085 19.1 4.9 9.8 5.8 0.0 5.3 6 0 0 6 6 6 0 AAA domain TsaE PF02367.17 OQR99244.1 - 0.00088 19.3 0.9 3.7 7.6 0.0 4.3 4 0 0 4 4 4 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE Rad17 PF03215.15 OQR99244.1 - 0.0013 18.7 0.1 12 5.7 0.0 4.5 4 0 0 4 4 4 0 Rad17 P-loop domain Sigma54_activat PF00158.26 OQR99244.1 - 0.0027 17.4 0.0 4.8 6.9 0.0 3.2 3 0 0 3 3 3 1 Sigma-54 interaction domain FtsK_SpoIIIE PF01580.18 OQR99244.1 - 0.0042 16.5 0.2 1.2 8.4 0.0 3.8 4 0 0 4 4 4 1 FtsK/SpoIIIE family Guanylate_kin PF00625.21 OQR99244.1 - 0.0097 15.6 0.1 12 5.5 0.0 4.2 4 0 0 4 4 2 0 Guanylate kinase AAA_29 PF13555.6 OQR99244.1 - 0.022 14.5 0.0 15 5.4 0.0 3.6 3 0 0 3 3 3 0 P-loop containing region of AAA domain AAA_lid_1 PF17857.1 OQR99244.1 - 0.022 15.0 0.2 0.17 12.1 0.0 2.6 2 0 0 2 2 1 0 AAA+ lid domain Roc PF08477.13 OQR99244.1 - 0.059 13.6 0.8 42 4.4 0.0 4.6 4 0 0 4 4 4 0 Ras of Complex, Roc, domain of DAPkinase OmpH PF03938.14 OQR99244.1 - 0.89 9.9 14.3 9 6.6 3.4 4.5 3 0 0 3 3 3 0 Outer membrane protein (OmpH-like) PSK_trans_fac PF07704.11 OQR99244.1 - 1.2 10.0 3.1 5.4 7.8 1.2 3.3 3 0 0 3 3 1 0 Rv0623-like transcription factor Ank_2 PF12796.7 OQR99245.1 - 2.6e-54 181.7 36.5 6.5e-08 33.1 0.1 12.9 4 3 9 13 13 13 11 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQR99245.1 - 2.9e-50 168.0 42.2 7.9e-07 29.5 0.0 18.5 12 4 6 19 19 19 11 Ankyrin repeats (many copies) Ank_5 PF13857.6 OQR99245.1 - 2.3e-47 158.4 45.7 0.0016 18.7 0.0 24.5 9 5 19 28 28 28 17 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQR99245.1 - 6.9e-32 105.9 29.0 0.88 10.3 0.0 23.1 22 4 4 26 26 26 7 Ankyrin repeat Ank PF00023.30 OQR99245.1 - 1.4e-05 25.3 19.3 31 5.2 0.4 13.3 12 4 3 15 15 15 0 Ankyrin repeat AhpC-TSA PF00578.21 OQR99245.1 - 0.17 11.8 0.0 31 4.5 0.0 3.5 3 0 0 3 3 3 0 AhpC/TSA family RNase_P_p30 PF01876.16 OQR99245.1 - 0.19 11.2 0.1 27 4.1 0.0 3.6 4 0 0 4 4 4 0 RNase P subunit p30 Ank_2 PF12796.7 OQR99246.1 - 1.1e-18 67.5 7.1 6e-09 36.4 0.1 3.9 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OQR99246.1 - 2e-15 56.6 7.7 0.13 12.7 0.1 7.8 4 2 4 8 8 8 5 Ankyrin repeats (many copies) Ank_4 PF13637.6 OQR99246.1 - 4.2e-15 55.9 12.9 0.0023 18.5 0.1 6.5 2 1 6 8 8 8 8 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQR99246.1 - 7.6e-08 32.0 7.2 38 5.3 0.0 8.2 7 2 2 9 9 9 0 Ankyrin repeat DUF3447 PF11929.8 OQR99246.1 - 1.5e-05 24.9 1.2 0.32 11.0 0.0 4.1 2 2 2 4 4 4 1 Domain of unknown function (DUF3447) Ank PF00023.30 OQR99246.1 - 4.3 8.0 9.7 50 4.6 0.0 5.9 5 2 0 5 5 5 0 Ankyrin repeat Mannosyl_trans3 PF11051.8 OQR99247.1 - 2.6e-33 115.6 0.0 4e-33 115.0 0.0 1.3 1 0 0 1 1 1 1 Mannosyltransferase putative Ank_2 PF12796.7 OQR99248.1 - 8.3e-05 23.1 0.1 0.00056 20.5 0.0 2.1 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQR99248.1 - 0.012 16.1 2.2 3.7 8.3 0.0 3.5 3 0 0 3 3 3 0 Ankyrin repeats (many copies) DFF-C PF09033.10 OQR99248.1 - 0.046 13.6 1.6 0.1 12.5 0.7 1.9 1 1 1 2 2 2 0 DNA Fragmentation factor 45kDa, C terminal domain DUF4347 PF14252.6 OQR99248.1 - 0.047 13.5 0.1 0.31 10.9 0.0 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4347) Ank_3 PF13606.6 OQR99248.1 - 0.18 12.4 0.3 2.1e+02 3.0 0.1 3.8 4 0 0 4 4 4 0 Ankyrin repeat Peptidase_S10 PF00450.22 OQR99249.1 - 4.4e-29 102.1 3.8 1.6e-14 54.2 0.2 3.1 1 1 2 3 3 3 3 Serine carboxypeptidase ANAPC2 PF08672.11 OQR99250.1 - 0.1 13.1 5.1 2.8 8.5 0.5 4.0 4 0 0 4 4 4 0 Anaphase promoting complex (APC) subunit 2 KLRAQ PF10205.9 OQR99250.1 - 0.36 11.1 12.9 0.14 12.4 3.1 2.9 1 1 1 2 2 2 0 Predicted coiled-coil domain-containing protein Cep57_MT_bd PF06657.13 OQR99250.1 - 0.53 10.8 11.7 0.26 11.7 0.7 4.0 3 1 1 4 4 4 0 Centrosome microtubule-binding domain of Cep57 BLOC1_2 PF10046.9 OQR99250.1 - 0.55 10.6 8.2 5 7.5 0.3 3.1 3 1 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 YlbE PF14003.6 OQR99250.1 - 1.8 9.1 3.9 1.4 9.4 0.1 2.8 3 0 0 3 3 3 0 YlbE-like protein TMCO5 PF14992.6 OQR99250.1 - 3.3 7.2 17.0 2.7 7.5 8.2 2.3 1 1 1 2 2 2 0 TMCO5 family Pkinase PF00069.25 OQR99307.1 - 1.9e-64 217.6 0.0 2.6e-64 217.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQR99307.1 - 8.5e-31 107.2 0.0 1.2e-30 106.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OQR99307.1 - 0.013 14.8 0.4 1.2 8.3 0.4 2.4 2 0 0 2 2 2 0 Kinase-like Kdo PF06293.14 OQR99307.1 - 0.014 14.8 0.0 0.024 14.0 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OQR99307.1 - 0.031 14.2 0.1 0.059 13.3 0.1 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family MAP65_ASE1 PF03999.12 OQR99307.1 - 7.5 5.1 9.0 12 4.5 9.0 1.2 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) ANAPC4_WD40 PF12894.7 OQR99308.1 - 3.9e-11 43.1 2.3 0.014 15.7 0.1 6.5 4 1 3 8 8 8 4 Anaphase-promoting complex subunit 4 WD40 domain Coatomer_WDAD PF04053.14 OQR99308.1 - 4.6e-09 35.8 0.8 0.00058 19.0 0.0 3.5 3 1 1 4 4 4 2 Coatomer WD associated region WD40 PF00400.32 OQR99308.1 - 3.1e-06 27.8 2.3 0.59 11.1 0.1 5.3 5 0 0 5 5 3 2 WD domain, G-beta repeat Clathrin PF00637.20 OQR99308.1 - 0.00012 22.0 2.8 0.022 14.6 0.1 4.3 2 1 1 4 4 4 1 Region in Clathrin and VPS eIF2A PF08662.11 OQR99308.1 - 0.0072 16.2 0.9 0.47 10.3 0.6 3.1 3 1 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A TPR_7 PF13176.6 OQR99308.1 - 0.01 15.8 4.4 2.3 8.5 0.1 5.1 4 1 1 5 5 5 0 Tetratricopeptide repeat GvpO PF05800.11 OQR99308.1 - 0.015 15.3 0.1 0.052 13.5 0.0 1.9 2 0 0 2 2 2 0 Gas vesicle synthesis protein GvpO TPR_12 PF13424.6 OQR99308.1 - 0.093 13.0 10.8 0.36 11.1 0.0 4.8 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_16 PF13432.6 OQR99308.1 - 0.11 13.2 13.4 4.7 7.9 0.1 5.5 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_14 PF13428.6 OQR99308.1 - 0.13 13.1 14.0 3.8 8.6 0.1 5.7 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_1 PF00515.28 OQR99308.1 - 0.32 10.9 13.0 0.49 10.3 0.5 4.9 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_2 PF07719.17 OQR99308.1 - 0.4 10.9 21.0 0.13 12.4 0.4 6.8 8 0 0 8 8 7 0 Tetratricopeptide repeat ANAPC3 PF12895.7 OQR99308.1 - 8.3 6.7 8.3 9.6 6.5 0.1 3.6 4 1 0 4 4 3 0 Anaphase-promoting complex, cyclosome, subunit 3 Exo_endo_phos PF03372.23 OQR99309.1 - 1.1e-15 57.8 0.1 1.8e-15 57.1 0.1 1.4 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family zf-GRF PF06839.12 OQR99309.1 - 2.4e-12 46.8 1.0 7.6e-12 45.1 1.0 2.0 1 0 0 1 1 1 1 GRF zinc finger Exo_endo_phos_2 PF14529.6 OQR99309.1 - 3.6e-05 23.6 0.1 0.00013 21.8 0.1 2.1 1 1 0 1 1 1 1 Endonuclease-reverse transcriptase ARL6IP6 PF15062.6 OQR99309.1 - 3.3 7.9 6.3 0.85 9.8 0.1 2.6 3 0 0 3 3 3 0 Haemopoietic lineage transmembrane helix KTI12 PF08433.10 OQR99310.1 - 7.3e-73 245.4 0.7 5.7e-72 242.4 0.7 1.9 1 1 0 1 1 1 1 Chromatin associated protein KTI12 AAA_33 PF13671.6 OQR99310.1 - 2.4e-15 57.0 0.2 5.5e-15 55.8 0.0 1.7 2 1 0 2 2 2 1 AAA domain APS_kinase PF01583.20 OQR99310.1 - 2.5e-06 27.5 0.0 4.7e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_18 PF13238.6 OQR99310.1 - 3.3e-06 27.7 0.0 6.1e-06 26.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 OQR99310.1 - 7.4e-05 23.2 0.1 0.0029 18.0 0.1 2.5 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 OQR99310.1 - 0.00029 20.6 1.0 0.00067 19.4 0.0 2.0 2 1 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 OQR99310.1 - 0.00032 20.5 0.2 0.00086 19.1 0.0 1.7 2 0 0 2 2 2 1 IstB-like ATP binding protein Zeta_toxin PF06414.12 OQR99310.1 - 0.0005 19.4 0.1 0.0022 17.3 0.0 2.0 1 1 0 2 2 2 1 Zeta toxin AAA_14 PF13173.6 OQR99310.1 - 0.0013 18.8 0.0 0.0022 18.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain SRP54 PF00448.22 OQR99310.1 - 0.0015 18.2 0.0 0.0031 17.2 0.0 1.6 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain AAA_16 PF13191.6 OQR99310.1 - 0.0016 18.8 0.1 0.0035 17.7 0.1 1.9 1 1 0 1 1 1 1 AAA ATPase domain Thymidylate_kin PF02223.17 OQR99310.1 - 0.0019 17.9 0.1 0.47 10.1 0.0 2.6 1 1 1 2 2 2 1 Thymidylate kinase AAA_17 PF13207.6 OQR99310.1 - 0.0019 18.6 1.1 0.0077 16.7 0.2 2.3 2 1 0 2 2 1 1 AAA domain MeaB PF03308.16 OQR99310.1 - 0.0023 16.9 0.3 0.0086 15.1 0.0 1.9 2 1 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB Viral_helicase1 PF01443.18 OQR99310.1 - 0.003 17.3 0.1 0.0045 16.8 0.1 1.6 1 1 0 1 1 1 1 Viral (Superfamily 1) RNA helicase Aldo_ket_red PF00248.21 OQR99310.1 - 0.0033 16.7 0.0 0.0047 16.2 0.0 1.5 1 1 0 1 1 1 1 Aldo/keto reductase family CPT PF07931.12 OQR99310.1 - 0.0034 17.2 0.0 0.025 14.4 0.0 2.2 2 1 0 2 2 2 1 Chloramphenicol phosphotransferase-like protein AAA_22 PF13401.6 OQR99310.1 - 0.0054 17.0 0.2 0.017 15.4 0.2 2.0 1 1 0 1 1 1 1 AAA domain DUF2075 PF09848.9 OQR99310.1 - 0.0097 15.2 0.0 0.013 14.8 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_5 PF07728.14 OQR99310.1 - 0.022 14.7 0.0 0.056 13.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_24 PF13479.6 OQR99310.1 - 0.025 14.3 0.0 0.046 13.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain CbiA PF01656.23 OQR99310.1 - 0.028 14.5 0.0 0.055 13.5 0.0 1.4 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain 6PF2K PF01591.18 OQR99310.1 - 0.028 13.7 0.1 0.13 11.6 0.1 1.9 1 1 1 2 2 2 0 6-phosphofructo-2-kinase ArsA_ATPase PF02374.15 OQR99310.1 - 0.028 13.6 0.0 0.041 13.1 0.0 1.3 1 0 0 1 1 1 0 Anion-transporting ATPase ADK PF00406.22 OQR99310.1 - 0.034 14.2 0.2 0.4 10.8 0.0 2.5 1 1 0 2 2 2 0 Adenylate kinase ATP_bind_1 PF03029.17 OQR99310.1 - 0.044 13.6 0.2 0.087 12.6 0.0 1.8 2 1 0 2 2 1 0 Conserved hypothetical ATP binding protein CBP_BcsQ PF06564.12 OQR99310.1 - 0.044 13.3 0.0 0.08 12.4 0.0 1.5 1 0 0 1 1 1 0 Cellulose biosynthesis protein BcsQ MipZ PF09140.11 OQR99310.1 - 0.045 13.0 0.0 0.066 12.5 0.0 1.2 1 0 0 1 1 1 0 ATPase MipZ Ploopntkinase1 PF18748.1 OQR99310.1 - 0.045 13.3 0.0 0.083 12.4 0.0 1.5 1 0 0 1 1 1 0 P-loop Nucleotide Kinase1 Mg_chelatase PF01078.21 OQR99310.1 - 0.046 13.1 0.0 0.076 12.4 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_28 PF13521.6 OQR99310.1 - 0.073 13.3 0.7 0.54 10.5 0.3 2.5 2 1 0 2 2 1 0 AAA domain Kinesin PF00225.23 OQR99311.1 - 2.1e-89 299.8 0.1 2.1e-89 299.8 0.1 1.6 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 OQR99311.1 - 3.9e-27 95.0 0.0 1.1e-26 93.6 0.0 1.8 1 0 0 1 1 1 1 Microtubule binding PH_12 PF16457.5 OQR99311.1 - 0.0025 18.4 1.7 0.022 15.3 0.0 2.6 2 0 0 2 2 2 1 Pleckstrin homology domain SlyX PF04102.12 OQR99311.1 - 0.028 15.1 3.0 0.028 15.1 3.0 2.8 3 0 0 3 3 3 0 SlyX T2SSE PF00437.20 OQR99311.1 - 0.084 11.9 2.3 0.34 9.9 0.0 2.2 2 0 0 2 2 2 0 Type II/IV secretion system protein DivIC PF04977.15 OQR99311.1 - 3.4 7.5 6.6 21 5.0 0.4 2.7 2 0 0 2 2 2 0 Septum formation initiator PAP_central PF04928.17 OQR99314.1 - 1.5e-69 233.8 0.0 6.7e-69 231.6 0.0 1.8 1 1 1 2 2 2 1 Poly(A) polymerase central domain PAP_RNA-bind PF04926.15 OQR99314.1 - 4.2e-06 26.5 0.0 1.9e-05 24.4 0.0 2.0 1 1 1 2 2 2 1 Poly(A) polymerase predicted RNA binding domain WD40 PF00400.32 OQR99315.1 - 8e-15 55.0 15.7 0.00029 21.6 0.3 8.1 9 0 0 9 9 9 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OQR99315.1 - 7.8e-13 48.5 5.9 0.0037 17.5 0.4 7.1 3 1 2 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 OQR99315.1 - 4.2e-05 23.5 5.7 0.002 18.1 0.2 4.5 3 1 1 5 5 5 1 Eukaryotic translation initiation factor eIF2A Coatomer_WDAD PF04053.14 OQR99315.1 - 7.5e-05 21.9 1.6 0.018 14.1 0.2 3.6 4 0 0 4 4 4 2 Coatomer WD associated region IKI3 PF04762.12 OQR99315.1 - 0.00086 17.4 0.5 0.44 8.5 0.0 3.3 2 1 0 2 2 2 1 IKI3 family Utp8 PF10395.9 OQR99315.1 - 0.071 11.6 0.0 0.11 10.9 0.0 1.2 1 0 0 1 1 1 0 Utp8 family Ras PF00071.22 OQR99316.1 - 1.7e-57 193.5 0.2 2.1e-57 193.2 0.2 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OQR99316.1 - 7.3e-37 126.2 0.1 1e-36 125.7 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OQR99316.1 - 5.1e-14 52.1 0.1 6.3e-14 51.8 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 OQR99316.1 - 8.9e-06 25.4 0.1 3.8e-05 23.3 0.1 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 OQR99316.1 - 2.1e-05 24.5 0.0 0.18 11.7 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase Gtr1_RagA PF04670.12 OQR99316.1 - 6.9e-05 22.3 0.3 0.00014 21.3 0.3 1.5 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 OQR99316.1 - 8.7e-05 22.0 0.0 0.00016 21.2 0.0 1.4 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 OQR99316.1 - 0.00055 20.0 0.0 0.0014 18.7 0.0 1.7 2 1 0 2 2 2 1 50S ribosome-binding GTPase AAA_7 PF12775.7 OQR99316.1 - 0.0067 16.0 0.0 0.012 15.1 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region FeoB_N PF02421.18 OQR99316.1 - 0.059 12.9 0.2 0.64 9.5 0.2 2.1 1 1 0 1 1 1 0 Ferrous iron transport protein B Pkinase PF00069.25 OQR99317.1 - 8.3e-65 218.8 0.0 1.4e-64 218.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQR99317.1 - 6.3e-38 130.5 0.0 1.6e-37 129.2 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase PH PF00169.29 OQR99317.1 - 1.6e-06 28.5 0.1 4.4e-06 27.2 0.0 1.8 2 0 0 2 2 2 1 PH domain PH_11 PF15413.6 OQR99317.1 - 0.00025 21.4 0.0 0.00063 20.1 0.0 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain Kinase-like PF14531.6 OQR99317.1 - 0.00095 18.6 0.0 0.0023 17.3 0.0 1.6 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 OQR99317.1 - 0.0015 18.0 0.3 0.0028 17.1 0.3 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 OQR99317.1 - 0.01 14.6 0.1 0.016 14.0 0.1 1.4 1 0 0 1 1 1 0 Fungal protein kinase Haspin_kinase PF12330.8 OQR99317.1 - 0.015 14.2 0.1 0.015 14.2 0.1 1.7 2 0 0 2 2 2 0 Haspin like kinase domain SnoaL_2 PF12680.7 OQR99317.1 - 0.038 14.6 0.0 0.099 13.3 0.0 1.7 1 0 0 1 1 1 0 SnoaL-like domain Ank_2 PF12796.7 OQR99318.1 - 1.6e-19 70.2 1.0 1e-16 61.3 0.3 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQR99318.1 - 3.7e-18 65.7 1.8 1.6e-07 31.7 0.0 3.2 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 OQR99318.1 - 4e-16 58.6 4.8 3.3e-06 27.3 0.4 4.1 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.6 OQR99318.1 - 9e-15 54.6 5.1 8e-08 32.4 0.4 2.7 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQR99318.1 - 4e-14 51.3 1.3 1.1e-05 25.4 0.1 4.0 4 0 0 4 4 4 3 Ankyrin repeat FMN_red PF03358.15 OQR99319.1 - 1.2e-26 93.3 0.0 1.8e-26 92.7 0.0 1.2 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 OQR99319.1 - 0.0039 16.9 0.0 0.0054 16.5 0.0 1.2 1 0 0 1 1 1 1 Flavodoxin-like fold Pkinase_Tyr PF07714.17 OQR99321.1 - 3.6e-18 65.8 0.1 9.2e-13 48.1 0.1 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 OQR99321.1 - 2.1e-12 47.0 1.1 4.8e-10 39.3 0.2 2.1 2 0 0 2 2 2 2 Protein kinase domain PX PF00787.24 OQR99322.1 - 0.0072 16.3 0.1 0.012 15.5 0.1 1.4 1 0 0 1 1 1 1 PX domain PI3_PI4_kinase PF00454.27 OQR99323.1 - 9.3e-25 87.9 0.0 1.4e-24 87.2 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase Stanniocalcin PF03298.13 OQR99324.1 - 0.00038 19.8 0.4 0.00046 19.6 0.4 1.1 1 0 0 1 1 1 1 Stanniocalcin family GCD14 PF08704.10 OQR99325.1 - 2.2e-77 260.1 0.0 2.8e-77 259.8 0.0 1.1 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit Methyltransf_31 PF13847.6 OQR99325.1 - 1.5e-08 34.6 0.0 2.4e-08 33.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OQR99325.1 - 1.1e-06 29.3 0.0 2.1e-06 28.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_24 PF13578.6 OQR99325.1 - 1.6e-05 25.9 0.0 4.2e-05 24.5 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain GCD14_N PF14801.6 OQR99325.1 - 2.3e-05 24.1 0.1 6.4e-05 22.7 0.1 1.7 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit N-term Methyltransf_11 PF08241.12 OQR99325.1 - 3e-05 24.6 0.0 6.1e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 OQR99325.1 - 0.0004 19.8 0.0 0.00064 19.1 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltr_RsmB-F PF01189.17 OQR99325.1 - 0.00064 19.4 0.0 0.001 18.8 0.0 1.3 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F PCMT PF01135.19 OQR99325.1 - 0.00069 19.4 0.0 0.0013 18.5 0.0 1.4 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_4 PF02390.17 OQR99325.1 - 0.035 13.6 0.0 0.053 13.0 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_12 PF08242.12 OQR99325.1 - 0.089 13.5 0.0 0.17 12.6 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain PrmA PF06325.13 OQR99325.1 - 0.096 12.1 0.0 0.13 11.6 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) PX PF00787.24 OQR99326.1 - 9.6e-18 64.2 0.0 1.5e-17 63.6 0.0 1.2 1 0 0 1 1 1 1 PX domain LAMTOR PF15454.6 OQR99326.1 - 0.057 14.0 0.4 0.11 13.1 0.4 1.5 1 0 0 1 1 1 0 Late endosomal/lysosomal adaptor and MAPK and MTOR activator DUF155 PF02582.14 OQR99327.1 - 2.4e-52 177.5 0.4 3.8e-52 176.9 0.4 1.3 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 DUF21 PF01595.20 OQR99328.1 - 2.9e-32 111.8 2.9 4.5e-32 111.2 2.9 1.2 1 0 0 1 1 1 1 Cyclin M transmembrane N-terminal domain CBS PF00571.28 OQR99328.1 - 0.00089 19.7 0.4 1.5 9.4 0.1 3.0 2 1 0 2 2 2 2 CBS domain Ank_2 PF12796.7 OQR99329.1 - 1.1e-33 115.6 4.2 9.9e-17 61.3 0.3 3.3 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQR99329.1 - 2.8e-28 97.9 1.5 9.3e-07 29.3 0.0 5.4 2 1 3 5 5 5 5 Ankyrin repeats (many copies) Ank PF00023.30 OQR99329.1 - 5.8e-27 92.9 2.4 4.8e-05 23.6 0.0 7.2 6 1 0 6 6 6 5 Ankyrin repeat Ank_5 PF13857.6 OQR99329.1 - 6.3e-24 83.7 2.7 2e-06 27.9 0.1 5.7 2 1 3 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQR99329.1 - 6.9e-23 78.3 0.5 0.023 15.2 0.0 7.8 7 0 0 7 7 7 5 Ankyrin repeat AA_permease_2 PF13520.6 OQR99330.1 - 7.3e-22 77.8 35.5 9e-22 77.5 35.5 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 OQR99330.1 - 7.4e-17 61.1 33.0 4e-16 58.7 33.0 2.0 1 1 0 1 1 1 1 Amino acid permease LmjF365940-deam PF14421.6 OQR99332.1 - 2.5e-56 190.4 0.0 3.6e-56 189.9 0.0 1.2 1 0 0 1 1 1 1 A distinct subfamily of CDD/CDA-like deaminases Snf7 PF03357.21 OQR99334.1 - 6.9e-27 94.1 14.7 1.3e-26 93.3 14.7 1.4 1 0 0 1 1 1 1 Snf7 Peptidase_S41 PF03572.18 OQR99334.1 - 6.7e-06 25.8 0.0 1.6e-05 24.6 0.0 1.6 1 1 0 1 1 1 1 Peptidase family S41 ParBc PF02195.18 OQR99334.1 - 5.2e-05 23.5 0.0 0.00013 22.2 0.0 1.6 1 0 0 1 1 1 1 ParB-like nuclease domain DUF883 PF05957.13 OQR99334.1 - 0.3 11.7 5.8 1.4 9.6 0.1 2.9 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) DivIC PF04977.15 OQR99334.1 - 0.37 10.6 8.6 0.97 9.2 8.6 1.6 1 0 0 1 1 1 0 Septum formation initiator TACC_C PF05010.14 OQR99334.1 - 0.89 9.3 14.7 1.6 8.5 14.3 1.6 1 1 0 1 1 1 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal Exonuc_VII_L PF02601.15 OQR99334.1 - 3.4 7.1 9.3 6.2 6.3 9.3 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit HTH_Tnp_Tc3_2 PF01498.18 OQR99394.1 - 0.035 14.4 0.0 0.09 13.0 0.0 1.6 1 0 0 1 1 1 0 Transposase IBR PF01485.21 OQR99397.1 - 3.3e-14 52.8 48.8 8.7e-08 32.3 20.1 3.4 2 1 1 3 3 3 3 IBR domain, a half RING-finger domain Peptidase_C69 PF03577.15 OQR99398.1 - 6.7e-45 153.7 0.3 3.5e-44 151.4 0.3 2.1 1 1 0 1 1 1 1 Peptidase family C69 PCI PF01399.27 OQR99399.1 - 0.0016 18.9 0.1 0.0016 18.9 0.1 3.1 4 0 0 4 4 4 1 PCI domain Peptidase_A3 PF02160.15 OQR99399.1 - 3.8 6.9 8.3 12 5.3 8.3 1.8 1 0 0 1 1 1 0 Cauliflower mosaic virus peptidase (A3) Pkinase_Tyr PF07714.17 OQR99400.1 - 1.5e-51 175.2 0.0 1.8e-51 174.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OQR99400.1 - 1.1e-48 165.9 0.0 1.6e-48 165.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 OQR99400.1 - 0.002 17.0 0.0 0.0028 16.5 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Gram_pos_anchor PF00746.21 OQR99400.1 - 0.0051 16.7 0.1 0.01 15.7 0.1 1.5 1 0 0 1 1 1 1 LPXTG cell wall anchor motif GFA PF04828.14 OQR99401.1 - 1.7e-08 34.7 0.9 1.7e-08 34.7 0.9 1.9 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme DAP_epimerase PF01678.19 OQR99402.1 - 2.8e-42 143.7 0.7 1.9e-21 76.5 0.0 2.0 2 0 0 2 2 2 2 Diaminopimelate epimerase Peripla_BP_3 PF13377.6 OQR99402.1 - 0.022 15.1 0.3 0.31 11.4 0.2 2.1 1 1 1 2 2 2 0 Periplasmic binding protein-like domain Ank_2 PF12796.7 OQR99403.1 - 6.2e-59 196.6 2.6 1.5e-16 60.8 0.0 4.6 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQR99403.1 - 2.1e-44 149.3 0.0 3.7e-11 43.3 0.0 4.9 2 1 3 5 5 5 5 Ankyrin repeats (many copies) Ank PF00023.30 OQR99403.1 - 8.8e-43 142.9 2.3 3.5e-06 27.2 0.0 7.9 7 0 0 7 7 7 7 Ankyrin repeat PLAC8 PF04749.17 OQR99403.1 - 1.1e-36 125.8 49.3 7.2e-18 65.4 22.6 3.6 3 0 0 3 3 3 3 PLAC8 family Ank_3 PF13606.6 OQR99403.1 - 2.5e-35 116.5 0.5 0.00019 21.6 0.0 8.4 8 0 0 8 8 8 7 Ankyrin repeat Ank_5 PF13857.6 OQR99403.1 - 7.4e-26 89.9 1.4 3.9e-07 30.2 0.2 6.3 2 2 4 6 6 6 6 Ankyrin repeats (many copies) DUF4497 PF14924.6 OQR99403.1 - 0.091 13.2 0.0 18 5.8 0.0 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF4497) Pkinase_Tyr PF07714.17 OQR99404.1 - 9.4e-11 41.5 0.0 2.4e-10 40.2 0.0 1.5 1 1 1 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.25 OQR99404.1 - 3.2e-09 36.5 0.0 4.8e-09 36.0 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain APH PF01636.23 OQR99404.1 - 0.093 12.6 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family PH PF00169.29 OQR99406.1 - 4.7e-05 23.8 1.0 8.8e-05 23.0 0.4 1.8 2 0 0 2 2 2 1 PH domain MIF4G PF02854.19 OQR99407.1 - 1.1e-50 172.3 6.7 2.9e-24 85.9 0.1 3.9 3 1 0 3 3 3 3 MIF4G domain Upf2 PF04050.14 OQR99407.1 - 2.7e-15 57.3 10.1 2.7e-15 57.3 10.1 3.5 2 1 1 3 3 3 1 Up-frameshift suppressor 2 Ank_2 PF12796.7 OQR99408.1 - 3.4e-20 72.4 8.6 2.3e-08 34.5 0.4 4.6 4 1 1 5 5 5 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQR99408.1 - 2e-18 66.5 5.7 7.6e-08 32.8 0.1 5.9 5 1 0 5 5 5 3 Ankyrin repeats (many copies) Ank PF00023.30 OQR99408.1 - 7.1e-12 45.2 6.6 0.00041 20.7 0.1 6.0 5 0 0 5 5 5 3 Ankyrin repeat Ank_5 PF13857.6 OQR99408.1 - 4.9e-11 42.7 1.0 0.0008 19.7 0.1 5.1 4 0 0 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQR99408.1 - 8.8e-10 38.0 5.0 0.016 15.7 0.0 7.2 8 0 0 8 8 8 2 Ankyrin repeat XPG_I PF00867.18 OQR99409.1 - 1.7e-26 92.4 0.0 3.3e-26 91.5 0.0 1.5 1 0 0 1 1 1 1 XPG I-region XPG_I_2 PF12813.7 OQR99409.1 - 3.2e-05 23.5 0.1 0.00045 19.8 0.0 2.1 2 0 0 2 2 2 1 XPG domain containing Oxidored_molyb PF00174.19 OQR99410.1 - 4.5e-55 185.9 0.0 6.6e-55 185.3 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.16 OQR99410.1 - 1.2e-41 141.9 0.5 2.5e-41 140.9 0.5 1.5 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain Cyt-b5 PF00173.28 OQR99410.1 - 2.7e-12 46.7 0.1 4.6e-12 45.9 0.1 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain BNR PF02012.20 OQR99410.1 - 0.54 10.5 0.1 0.54 10.5 0.1 2.8 3 0 0 3 3 3 0 BNR/Asp-box repeat PH PF00169.29 OQR99411.1 - 1.3e-10 41.7 0.0 2.3e-10 40.9 0.0 1.4 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 OQR99411.1 - 0.0085 16.5 0.6 0.026 14.9 0.6 1.8 1 1 0 1 1 1 1 Pleckstrin homology domain PH_8 PF15409.6 OQR99411.1 - 0.012 15.9 0.0 0.024 14.9 0.0 1.7 1 1 0 1 1 1 0 Pleckstrin homology domain DUF4200 PF13863.6 OQR99412.1 - 9.3e-31 106.7 26.9 9.3e-31 106.7 26.9 2.9 3 0 0 3 3 3 2 Domain of unknown function (DUF4200) BAR_3 PF16746.5 OQR99412.1 - 1.5e-06 28.1 11.3 1.5e-06 28.1 11.3 2.1 1 1 1 2 2 2 1 BAR domain of APPL family WWE PF02825.20 OQR99412.1 - 0.0026 18.3 2.3 1.7 9.3 0.0 2.9 2 0 0 2 2 2 2 WWE domain HK97-gp10_like PF04883.12 OQR99412.1 - 1.7 9.7 5.4 0.32 12.0 0.3 2.5 3 0 0 3 3 3 0 Bacteriophage HK97-gp10, putative tail-component Mei5_like PF17021.5 OQR99412.1 - 1.9 8.5 13.2 0.34 11.0 7.9 2.4 1 1 0 2 2 2 0 Putative double-strand recombination repair-like DUF4349 PF14257.6 OQR99412.1 - 2.8 7.3 15.8 0.04 13.4 1.8 3.3 2 1 1 4 4 4 0 Domain of unknown function (DUF4349) EF-hand_14 PF17959.1 OQR99412.1 - 6 7.3 8.2 20 5.6 4.2 3.3 1 1 1 2 2 2 0 EF-hand domain LRR_8 PF13855.6 OQR99413.1 - 2.1e-26 91.4 26.9 1.1e-08 34.7 1.5 3.2 1 1 4 5 5 5 5 Leucine rich repeat LRR_4 PF12799.7 OQR99413.1 - 1.2e-15 57.3 18.7 1.5e-05 25.2 1.4 4.3 1 1 2 4 4 4 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 OQR99413.1 - 2.6e-06 27.2 14.6 1.2 9.9 0.2 6.1 6 0 0 6 6 6 4 Leucine Rich Repeat FBA_1 PF07734.13 OQR99413.1 - 0.013 15.4 0.0 0.021 14.7 0.0 1.3 1 0 0 1 1 1 0 F-box associated LRR_6 PF13516.6 OQR99413.1 - 0.51 10.5 12.5 14 6.0 0.2 5.4 6 0 0 6 6 6 0 Leucine Rich repeat Pkinase PF00069.25 OQR99415.1 - 5.5e-75 252.1 0.0 6.5e-75 251.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQR99415.1 - 1.9e-32 112.5 0.0 2.9e-32 112.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OQR99415.1 - 2.7e-06 26.9 0.1 0.00028 20.3 0.0 2.4 1 1 1 2 2 2 2 Kinase-like Haspin_kinase PF12330.8 OQR99415.1 - 0.00039 19.5 0.1 0.0058 15.6 0.1 2.0 1 1 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 OQR99415.1 - 0.0044 16.4 0.1 0.0082 15.5 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 OQR99415.1 - 0.0073 15.9 0.0 0.01 15.4 0.0 1.2 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 OQR99415.1 - 0.012 15.5 0.1 0.046 13.6 0.0 1.9 2 0 0 2 2 2 0 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.9 OQR99415.1 - 0.037 13.5 0.0 0.054 13.0 0.0 1.2 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL FTA2 PF13095.6 OQR99415.1 - 0.084 12.5 0.1 2.5 7.7 0.0 2.1 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 DUF2431 PF10354.9 OQR99416.1 - 1.2e-43 149.3 0.0 1.7e-43 148.8 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF2431) Cas9_b_hairpin PF17893.1 OQR99416.1 - 0.11 12.3 0.0 0.74 9.7 0.0 2.3 2 1 0 2 2 2 0 CRISPR-associated endonuclease Cas9 beta-hairpin domain GST_C_4 PF14834.6 OQR99416.1 - 0.14 12.6 0.0 2.5 8.5 0.0 2.2 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain CBS PF00571.28 OQR99417.1 - 6e-24 84.3 0.3 2.7e-05 24.5 0.0 4.6 4 0 0 4 4 4 4 CBS domain PB1 PF00564.24 OQR99417.1 - 1e-07 31.8 0.0 2.6e-07 30.5 0.0 1.7 1 0 0 1 1 1 1 PB1 domain Pilin_GH PF16734.5 OQR99417.1 - 0.035 14.4 0.1 0.072 13.4 0.1 1.5 1 0 0 1 1 1 0 Type IV pilin-like G and H, putative Gtr1_RagA PF04670.12 OQR99417.1 - 0.042 13.2 0.0 0.086 12.2 0.0 1.4 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region GSHPx PF00255.19 OQR99418.1 - 2.6e-07 30.2 0.0 3.8e-07 29.6 0.0 1.2 1 0 0 1 1 1 1 Glutathione peroxidase Ank_2 PF12796.7 OQR99420.1 - 7.8e-93 305.2 13.3 2.8e-20 72.7 0.6 9.8 5 2 5 10 10 10 9 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQR99420.1 - 1.4e-74 245.5 21.8 2.6e-13 50.2 0.1 11.6 8 3 3 11 11 11 10 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQR99420.1 - 5e-71 226.2 22.8 6.2e-06 26.2 0.0 16.5 15 0 0 15 15 15 12 Ankyrin repeat Ank PF00023.30 OQR99420.1 - 1.1e-67 221.6 39.1 6.9e-09 35.8 0.0 15.7 15 0 0 15 15 15 12 Ankyrin repeat Ank_5 PF13857.6 OQR99420.1 - 5.4e-67 221.0 32.9 3.9e-10 39.8 0.3 13.7 7 6 9 16 16 16 10 Ankyrin repeats (many copies) zf-C3HC4_3 PF13920.6 OQR99420.1 - 4.8e-15 55.2 43.4 2.9e-08 33.5 8.9 6.8 7 0 0 7 7 7 3 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 OQR99420.1 - 0.00065 19.5 11.2 0.00065 19.5 11.2 6.3 6 0 0 6 6 6 3 Zinc finger, C3HC4 type (RING finger) FeS PF04060.13 OQR99420.1 - 0.0021 17.6 12.0 0.28 10.9 1.0 4.7 3 0 0 3 3 3 2 Putative Fe-S cluster zf-C3HC4 PF00097.25 OQR99420.1 - 0.0033 17.3 12.1 0.0033 17.3 12.1 6.6 8 1 0 8 8 7 3 Zinc finger, C3HC4 type (RING finger) zf-RanBP PF00641.18 OQR99420.1 - 0.012 14.9 36.6 0.038 13.3 1.2 5.3 5 0 0 5 5 4 0 Zn-finger in Ran binding protein and others DZR PF12773.7 OQR99420.1 - 0.023 14.7 63.9 0.038 14.0 11.4 6.9 3 3 2 5 5 4 0 Double zinc ribbon DUF1843 PF08898.10 OQR99420.1 - 0.087 13.3 3.5 13 6.3 0.1 3.6 3 0 0 3 3 3 0 Domain of unknown function (DUF1843) zf-RING_UBOX PF13445.6 OQR99420.1 - 4.2 7.5 46.7 0.13 12.3 9.9 4.9 4 0 0 4 4 4 0 RING-type zinc-finger DUF2218 PF09981.9 OQR99421.1 - 0.11 12.8 0.0 0.15 12.4 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2218) CHAT PF12770.7 OQR99430.1 - 6.2e-14 52.1 0.2 1.1e-13 51.2 0.2 1.4 1 0 0 1 1 1 1 CHAT domain ABC_membrane PF00664.23 OQR99430.1 - 2.7e-08 33.8 5.3 4.9e-08 33.0 5.3 1.3 1 0 0 1 1 1 1 ABC transporter transmembrane region IstB_IS21 PF01695.17 OQR99430.1 - 0.0016 18.2 0.1 0.003 17.3 0.1 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_14 PF13173.6 OQR99430.1 - 0.0019 18.2 0.0 0.0037 17.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain NACHT PF05729.12 OQR99430.1 - 0.0053 16.7 0.1 0.015 15.2 0.0 1.8 2 0 0 2 2 2 1 NACHT domain AAA_16 PF13191.6 OQR99430.1 - 0.04 14.3 1.1 0.98 9.8 0.3 2.6 2 1 0 2 2 2 0 AAA ATPase domain Raptor_N PF14538.6 OQR99430.1 - 0.07 13.1 0.0 0.16 11.9 0.0 1.6 1 0 0 1 1 1 0 Raptor N-terminal CASPase like domain DUF4731 PF15875.5 OQR99430.1 - 0.09 13.0 0.5 0.46 10.7 0.3 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4731) AAA_22 PF13401.6 OQR99430.1 - 0.15 12.3 0.1 0.53 10.5 0.1 2.0 1 1 0 1 1 1 0 AAA domain SIKE PF05769.11 OQR99441.1 - 0.00072 19.5 2.9 0.001 19.0 2.9 1.3 1 0 0 1 1 1 1 SIKE family betaPIX_CC PF16523.5 OQR99441.1 - 0.032 14.0 1.4 1.4 8.8 0.1 2.3 2 0 0 2 2 2 0 betaPIX coiled coil CorA PF01544.18 OQR99441.1 - 0.18 11.1 2.7 0.24 10.7 2.7 1.1 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein JIP_LZII PF16471.5 OQR99441.1 - 0.23 11.6 3.9 0.67 10.2 0.5 2.3 2 0 0 2 2 2 0 JNK-interacting protein leucine zipper II Oxidored_q6 PF01058.22 OQR99442.1 - 2.6e-23 82.3 0.0 3.8e-23 81.7 0.0 1.3 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit Secapin PF17521.2 OQR99442.1 - 0.03 14.1 0.5 0.14 12.0 0.0 2.1 2 0 0 2 2 2 0 Honey bee peptides AA_permease_2 PF13520.6 OQR99443.1 - 2.1e-46 158.7 39.7 2.8e-46 158.2 39.7 1.1 1 0 0 1 1 1 1 Amino acid permease Mannosyl_trans3 PF11051.8 OQR99444.1 - 8.5e-36 123.7 0.2 1.1e-34 120.0 0.2 2.2 1 1 0 1 1 1 1 Mannosyltransferase putative START PF01852.19 OQR99445.1 - 7.6e-16 58.1 0.3 3.6e-08 33.1 0.0 2.4 2 0 0 2 2 2 2 START domain FYVE PF01363.21 OQR99445.1 - 2.8e-06 27.3 20.8 0.0059 16.7 9.6 2.7 2 0 0 2 2 2 2 FYVE zinc finger Fer2_3 PF13085.6 OQR99445.1 - 0.0017 18.4 1.7 0.0017 18.4 1.7 3.4 3 0 0 3 3 3 1 2Fe-2S iron-sulfur cluster binding domain FYVE_2 PF02318.16 OQR99445.1 - 0.003 17.7 28.3 0.13 12.4 7.6 3.1 3 0 0 3 3 3 2 FYVE-type zinc finger Siva PF05458.12 OQR99445.1 - 0.076 12.7 23.5 0.5 10.0 6.4 2.6 2 0 0 2 2 2 0 Cd27 binding protein (Siva) FYVE PF01363.21 OQR99446.1 - 5.3e-09 36.1 15.6 1e-08 35.2 15.6 1.4 1 0 0 1 1 1 1 FYVE zinc finger START PF01852.19 OQR99446.1 - 3.4e-08 33.2 1.2 5.4e-08 32.5 0.0 1.8 2 0 0 2 2 2 1 START domain FYVE_2 PF02318.16 OQR99446.1 - 0.0006 20.0 10.6 0.00069 19.8 9.0 1.9 2 0 0 2 2 2 1 FYVE-type zinc finger FYVE PF01363.21 OQR99447.1 - 1.4e-08 34.8 10.2 1.4e-08 34.8 10.2 2.1 2 1 0 2 2 2 1 FYVE zinc finger START PF01852.19 OQR99447.1 - 2.9e-07 30.1 0.2 4.7e-07 29.4 0.2 1.4 1 0 0 1 1 1 1 START domain FYVE_2 PF02318.16 OQR99447.1 - 5.6e-05 23.3 8.4 5.6e-05 23.3 8.4 2.0 2 0 0 2 2 2 1 FYVE-type zinc finger Prok-RING_4 PF14447.6 OQR99447.1 - 5.1 7.0 10.9 24 4.9 9.3 2.3 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 TED_complement PF07678.14 OQR99448.1 - 0.1 11.6 0.0 0.12 11.4 0.0 1.1 1 0 0 1 1 1 0 A-macroglobulin TED domain FYVE PF01363.21 OQR99451.1 - 4.2e-15 55.6 7.1 1.3e-14 54.1 7.1 1.8 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.16 OQR99451.1 - 0.00026 21.2 4.7 0.00073 19.7 3.5 2.4 2 0 0 2 2 2 1 FYVE-type zinc finger Meiotic_rec114 PF03525.14 OQR99451.1 - 0.0039 16.2 0.3 0.0069 15.4 0.3 1.3 1 0 0 1 1 1 1 Meiotic recombination protein rec114 BLOC1_2 PF10046.9 OQR99451.1 - 0.3 11.4 5.8 0.057 13.7 1.4 2.2 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Pkinase_Tyr PF07714.17 OQR99453.1 - 4.1e-17 62.3 0.0 8.1e-17 61.4 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OQR99453.1 - 7.7e-11 41.8 0.0 1.5e-10 40.9 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Capsid-VNN PF11729.8 OQR99453.1 - 0.087 11.8 0.0 0.13 11.3 0.0 1.2 1 0 0 1 1 1 0 nodavirus capsid protein Ribosomal_L22 PF00237.19 OQR99454.1 - 0.0023 18.1 0.4 0.45 10.8 0.3 3.0 2 0 0 2 2 2 2 Ribosomal protein L22p/L17e EBV-NA3 PF05009.12 OQR99454.1 - 3.7 7.0 7.0 15 5.0 7.0 2.1 1 0 0 1 1 1 0 Epstein-Barr virus nuclear antigen 3 (EBNA-3) DUF924 PF06041.11 OQR99455.1 - 2.1e-48 164.8 0.2 2.4e-48 164.6 0.2 1.0 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF924) Pex24p PF06398.11 OQR99456.1 - 1.4e-09 37.4 1.2 2e-09 36.9 1.2 1.2 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin PDZ PF00595.24 OQR99456.1 - 3.1e-06 27.4 0.1 0.0075 16.6 0.1 2.7 2 1 0 2 2 2 2 PDZ domain PDZ_6 PF17820.1 OQR99456.1 - 0.0026 17.6 0.3 0.24 11.3 0.1 2.5 2 0 0 2 2 2 2 PDZ domain HSF_DNA-bind PF00447.17 OQR99457.1 - 2.1e-24 86.0 1.3 2.1e-24 86.0 1.3 1.6 2 0 0 2 2 2 1 HSF-type DNA-binding DUF2959 PF11172.8 OQR99457.1 - 0.046 13.9 0.5 0.082 13.0 0.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2959) DEAD PF00270.29 OQR99467.1 - 3.7e-46 157.1 0.0 6.2e-46 156.4 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OQR99467.1 - 1.8e-30 105.6 0.2 7.6e-29 100.3 0.0 3.0 2 1 1 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 OQR99467.1 - 5.9e-08 32.9 0.0 1e-07 32.1 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_30 PF13604.6 OQR99467.1 - 0.052 13.3 0.0 0.14 11.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain ABC2_membrane PF01061.24 OQR99469.1 - 5.9e-22 78.1 30.4 5.3e-12 45.6 17.6 2.1 1 1 1 2 2 2 2 ABC-2 type transporter ABC_tran PF00005.27 OQR99470.1 - 4.3e-17 62.9 0.0 3.9e-12 46.8 0.0 2.5 2 0 0 2 2 2 2 ABC transporter AAA_29 PF13555.6 OQR99470.1 - 0.0079 15.9 0.1 0.019 14.7 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 OQR99470.1 - 0.034 14.1 0.0 0.085 12.8 0.0 1.7 1 1 0 1 1 1 0 RsgA GTPase AAA_23 PF13476.6 OQR99470.1 - 0.053 14.0 0.0 0.11 13.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain Tctex-1 PF03645.13 OQR99474.1 - 1.1e-23 83.4 0.4 1.3e-23 83.2 0.4 1.0 1 0 0 1 1 1 1 Tctex-1 family TOC159_MAD PF11886.8 OQR99474.1 - 0.001 18.0 0.1 0.0012 17.9 0.1 1.1 1 0 0 1 1 1 1 Translocase of chloroplast 159/132, membrane anchor domain Integrase_DNA PF02920.15 OQR99474.1 - 0.014 15.1 0.2 0.029 14.1 0.0 1.5 2 0 0 2 2 2 0 DNA binding domain of tn916 integrase Cys_rich_CPCC PF14206.6 OQR99474.1 - 0.1 12.5 0.1 0.17 11.7 0.1 1.4 1 0 0 1 1 1 0 Cysteine-rich CPCC GTP_EFTU PF00009.27 OQR99475.1 - 1.1e-32 113.2 1.6 2.2e-30 105.7 1.6 2.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.8 OQR99475.1 - 1.6e-23 82.8 0.4 4.7e-23 81.3 0.4 1.8 1 0 0 1 1 1 1 Translation-initiation factor 2 MMR_HSR1 PF01926.23 OQR99475.1 - 9.4e-09 35.4 0.0 3.2e-08 33.7 0.0 2.0 1 0 0 1 1 1 1 50S ribosome-binding GTPase Arf PF00025.21 OQR99475.1 - 8.4e-06 25.3 0.0 2e-05 24.1 0.0 1.6 1 0 0 1 1 1 1 ADP-ribosylation factor family IF2_N PF04760.15 OQR99475.1 - 1.4e-05 24.8 0.0 4.3e-05 23.2 0.0 1.9 1 0 0 1 1 1 1 Translation initiation factor IF-2, N-terminal region PduV-EutP PF10662.9 OQR99475.1 - 3.8e-05 23.5 0.0 9.7e-05 22.1 0.0 1.7 1 0 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation RsgA_GTPase PF03193.16 OQR99475.1 - 0.00011 22.1 5.0 0.0023 17.8 0.1 2.9 2 1 1 3 3 3 1 RsgA GTPase Roc PF08477.13 OQR99475.1 - 0.011 15.9 0.0 0.04 14.2 0.0 1.9 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 OQR99475.1 - 0.016 14.6 0.0 0.039 13.4 0.0 1.7 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit ATP_bind_1 PF03029.17 OQR99475.1 - 0.021 14.6 0.0 0.12 12.2 0.0 2.2 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein MeaB PF03308.16 OQR99475.1 - 0.027 13.5 0.7 0.059 12.4 0.3 1.7 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB DUF3299 PF11736.8 OQR99475.1 - 0.051 13.6 0.2 0.21 11.6 0.1 2.1 2 0 0 2 2 1 0 Protein of unknown function (DUF3299) Polysacc_deac_1 PF01522.21 OQR99475.1 - 0.071 13.0 0.1 0.43 10.5 0.0 2.3 2 0 0 2 2 2 0 Polysaccharide deacetylase Ras PF00071.22 OQR99475.1 - 0.076 12.6 0.1 0.22 11.1 0.0 1.9 2 0 0 2 2 2 0 Ras family MMR_HSR1_Xtn PF16897.5 OQR99475.1 - 0.088 12.8 0.2 0.31 11.1 0.0 2.1 2 0 0 2 2 1 0 C-terminal region of MMR_HSR1 domain GTP_EFTU_D2 PF03144.25 OQR99475.1 - 0.14 12.5 0.6 0.54 10.7 0.2 2.3 2 0 0 2 2 1 0 Elongation factor Tu domain 2 ABC_tran PF00005.27 OQR99475.1 - 0.71 10.4 4.1 0.91 10.0 0.0 2.9 2 1 0 2 2 1 0 ABC transporter AAA_23 PF13476.6 OQR99475.1 - 4.3 7.8 0.0 4.3 7.8 0.0 3.5 4 0 0 4 4 4 0 AAA domain MT PF12777.7 OQR99480.1 - 6.5e-14 51.7 0.0 6.5e-14 51.7 0.0 3.0 3 0 0 3 3 3 1 Microtubule-binding stalk of dynein motor IQ PF00612.27 OQR99480.1 - 3.8 7.6 51.2 5 7.2 0.1 9.5 9 0 0 9 9 9 0 IQ calmodulin-binding motif ABC_tran PF00005.27 OQR99491.1 - 1.6e-31 109.6 0.0 3.2e-31 108.7 0.0 1.5 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.23 OQR99491.1 - 7.5e-20 71.7 10.8 1.2e-19 71.1 10.8 1.3 1 0 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.19 OQR99491.1 - 4.9e-10 39.2 0.2 4.5e-09 36.1 0.2 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 OQR99491.1 - 0.0019 18.5 0.3 0.0096 16.2 0.3 2.1 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 OQR99491.1 - 0.0067 16.8 0.1 0.018 15.4 0.1 1.7 1 1 0 1 1 1 1 AAA ATPase domain DEAD PF00270.29 OQR99491.1 - 0.012 15.4 1.4 0.04 13.7 1.4 1.9 1 1 0 1 1 1 0 DEAD/DEAH box helicase AAA_15 PF13175.6 OQR99491.1 - 0.014 15.1 1.3 0.028 14.1 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain AAA_25 PF13481.6 OQR99491.1 - 0.023 14.3 0.2 0.14 11.7 0.1 2.0 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.14 OQR99491.1 - 0.065 13.2 0.1 0.27 11.2 0.1 2.0 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_29 PF13555.6 OQR99491.1 - 0.069 12.9 0.6 0.17 11.6 0.6 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain CAF1C_H4-bd PF12265.8 OQR99491.1 - 0.078 13.3 0.0 9.6 6.6 0.0 3.3 3 0 0 3 3 3 0 Histone-binding protein RBBP4 or subunit C of CAF1 complex Sigma54_activat PF00158.26 OQR99491.1 - 0.095 12.4 0.0 0.31 10.7 0.0 1.8 1 0 0 1 1 1 0 Sigma-54 interaction domain RseC_MucC PF04246.12 OQR99491.1 - 0.099 12.6 3.8 0.82 9.6 0.7 2.5 2 0 0 2 2 2 0 Positive regulator of sigma(E), RseC/MucC AAA_21 PF13304.6 OQR99491.1 - 0.14 11.9 0.1 0.31 10.8 0.1 1.6 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 OQR99491.1 - 0.22 12.0 0.2 0.22 12.0 0.2 2.2 3 0 0 3 3 3 0 AAA domain EI24 PF07264.11 OQR99491.1 - 8.3 6.6 8.6 11 6.2 4.3 2.1 2 0 0 2 2 2 0 Etoposide-induced protein 2.4 (EI24) Pkinase_Tyr PF07714.17 OQR99492.1 - 7.4e-49 166.4 0.0 2.3e-47 161.5 0.0 2.4 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OQR99492.1 - 3.1e-48 164.5 0.0 1.2e-46 159.2 0.0 2.2 1 1 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 OQR99492.1 - 0.0033 16.3 0.1 0.0095 14.7 0.0 1.6 2 0 0 2 2 2 1 Fungal protein kinase CSN5_C PF18323.1 OQR99499.1 - 0.17 12.8 0.1 24 6.0 0.1 2.8 2 0 0 2 2 2 0 Cop9 signalosome subunit 5 C-terminal domain IQ PF00612.27 OQR99501.1 - 0.00013 21.5 49.1 0.13 12.1 0.3 8.0 6 1 1 7 7 7 5 IQ calmodulin-binding motif zf-C2H2 PF00096.26 OQR99501.1 - 0.0035 17.7 2.5 0.0035 17.7 2.5 4.0 3 0 0 3 3 3 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 OQR99501.1 - 0.017 15.9 2.7 0.017 15.9 2.7 4.5 3 0 0 3 3 3 0 C2H2-type zinc finger Haem_degrading PF03928.14 OQR99501.1 - 0.074 13.1 0.1 0.2 11.7 0.1 1.7 1 0 0 1 1 1 0 Haem-degrading zf-C2H2_8 PF15909.5 OQR99501.1 - 0.5 10.7 8.9 3.5 8.0 0.2 3.9 4 0 0 4 4 4 0 C2H2-type zinc ribbon zf-C2H2_6 PF13912.6 OQR99501.1 - 0.63 10.1 4.9 7.7 6.6 4.2 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger FYVE PF01363.21 OQR99502.1 - 2.4e-05 24.4 27.1 5.6e-05 23.2 22.5 3.1 1 1 1 2 2 2 1 FYVE zinc finger zf-RING_11 PF17123.5 OQR99502.1 - 4.9e-05 23.0 0.8 4.9e-05 23.0 0.8 2.5 2 0 0 2 2 2 1 RING-like zinc finger zf-RING_2 PF13639.6 OQR99502.1 - 0.00011 22.4 5.2 0.00011 22.4 5.2 3.6 2 1 1 3 3 3 1 Ring finger domain zf-HC5HC2H PF13771.6 OQR99502.1 - 0.025 14.8 3.1 0.025 14.8 3.1 3.6 1 1 1 3 3 3 0 PHD-like zinc-binding domain DUF2175 PF09943.9 OQR99502.1 - 0.04 14.2 8.2 0.077 13.3 0.9 2.4 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2175) zf-C2HC5 PF06221.13 OQR99502.1 - 0.47 10.5 15.1 13 5.9 10.6 3.5 2 1 1 3 3 3 0 Putative zinc finger motif, C2HC5-type PH PF00169.29 OQR99503.1 - 0.019 15.5 3.2 0.02 15.4 0.0 2.4 3 0 0 3 3 3 0 PH domain DAG_kinase_N PF14513.6 OQR99503.1 - 0.2 11.9 10.0 0.17 12.0 2.9 2.3 2 0 0 2 2 2 0 Diacylglycerol kinase N-terminus DHC_N1 PF08385.12 OQR99507.1 - 2.8e-32 112.1 2.2 3.5e-32 111.8 2.2 1.1 1 0 0 1 1 1 1 Dynein heavy chain, N-terminal region 1 Rav1p_C PF12234.8 OQR99508.1 - 0.0048 15.4 0.0 0.012 14.0 0.0 1.6 2 0 0 2 2 2 1 RAVE protein 1 C terminal PDZ_6 PF17820.1 OQR99508.1 - 0.005 16.7 0.0 0.013 15.4 0.0 1.7 1 0 0 1 1 1 1 PDZ domain CAF1A PF12253.8 OQR99508.1 - 0.021 15.0 1.5 0.34 11.1 2.6 2.2 2 0 0 2 2 2 0 Chromatin assembly factor 1 subunit A PDZ PF00595.24 OQR99508.1 - 0.12 12.8 0.0 0.26 11.6 0.0 1.5 1 0 0 1 1 1 0 PDZ domain WD40 PF00400.32 OQR99508.1 - 0.88 10.6 0.0 0.88 10.6 0.0 4.0 3 1 0 3 3 3 0 WD domain, G-beta repeat Copine PF07002.16 OQR99510.1 - 1.4e-79 266.6 0.1 1.1e-65 221.1 0.0 2.5 3 0 0 3 3 3 2 Copine vWA-TerF-like PF10138.9 OQR99510.1 - 4.8e-11 43.2 0.0 1.3e-10 41.7 0.0 1.8 2 1 0 2 2 2 1 vWA found in TerF C terminus VWA PF00092.28 OQR99510.1 - 0.0013 19.1 0.0 0.0024 18.1 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain Mersacidin PF16934.5 OQR99510.1 - 0.066 13.0 0.0 2 8.2 0.0 2.4 2 0 0 2 2 2 0 Two-component Enterococcus faecalis cytolysin (EFC) VWA_3 PF13768.6 OQR99510.1 - 0.15 11.9 0.0 0.35 10.8 0.0 1.7 1 1 0 1 1 1 0 von Willebrand factor type A domain FA_hydroxylase PF04116.13 OQR99512.1 - 6.3e-59 198.1 39.4 1.8e-30 106.0 11.0 3.1 4 0 0 4 4 4 2 Fatty acid hydroxylase superfamily LNS2 PF08235.13 OQR99514.1 - 2.9e-35 121.8 0.0 2.1e-33 115.7 0.0 2.1 1 1 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) Lipin_N PF04571.14 OQR99514.1 - 1.3e-11 44.3 0.1 5.3e-11 42.4 0.0 1.9 1 1 1 2 2 2 1 lipin, N-terminal conserved region UQ_con PF00179.26 OQR99515.1 - 3.1e-18 65.8 0.0 4.2e-18 65.3 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 OQR99515.1 - 0.085 12.6 0.0 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 Prokaryotic E2 family B GTP_cyclohydroI PF01227.22 OQR99516.1 - 2.9e-74 248.4 0.4 3.5e-74 248.1 0.4 1.1 1 0 0 1 1 1 1 GTP cyclohydrolase I Aminotran_1_2 PF00155.21 OQR99516.1 - 0.031 13.4 0.0 0.047 12.9 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class I and II zf-CXXC PF02008.20 OQR99517.1 - 1.2e-18 66.9 51.5 8.2e-11 41.8 15.9 3.1 3 0 0 3 3 3 2 CXXC zinc finger domain FHA PF00498.26 OQR99517.1 - 0.0043 17.4 0.0 0.0088 16.4 0.0 1.5 1 0 0 1 1 1 1 FHA domain zf-C2H2_4 PF13894.6 OQR99517.1 - 0.029 15.2 1.4 0.029 15.2 1.4 5.1 5 0 0 5 5 5 0 C2H2-type zinc finger CBP4 PF07960.11 OQR99517.1 - 0.17 11.7 1.0 0.52 10.2 1.0 1.8 1 0 0 1 1 1 0 CBP4 zf-C2H2_jaz PF12171.8 OQR99517.1 - 0.18 12.2 2.3 0.57 10.5 0.9 2.4 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding Mob_synth_C PF06463.13 OQR99518.1 - 4.8e-35 120.3 0.0 1.3e-34 118.9 0.0 1.7 2 0 0 2 2 2 1 Molybdenum Cofactor Synthesis C Radical_SAM PF04055.21 OQR99518.1 - 1e-27 97.6 0.0 1.6e-27 96.9 0.0 1.3 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_12 PF13353.6 OQR99518.1 - 3.4e-08 33.9 0.0 1e-07 32.3 0.0 1.8 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_14 PF13394.6 OQR99518.1 - 2.9e-05 24.2 0.0 8e-05 22.8 0.0 1.7 1 0 0 1 1 1 1 4Fe-4S single cluster domain LIAS_N PF16881.5 OQR99518.1 - 0.012 16.0 0.0 0.022 15.2 0.0 1.4 1 0 0 1 1 1 0 N-terminal domain of lipoyl synthase of Radical_SAM family Metallophos PF00149.28 OQR99519.1 - 7.3e-30 105.0 0.0 9.4e-30 104.6 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase His_Phos_2 PF00328.22 OQR99520.1 - 9.6e-07 28.5 0.0 0.0024 17.3 0.0 3.0 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Methyltr_RsmB-F PF01189.17 OQR99521.1 - 5.9e-40 137.0 0.0 1.4e-38 132.6 0.0 2.2 1 1 0 1 1 1 1 16S rRNA methyltransferase RsmB/F PUA PF01472.20 OQR99521.1 - 5.7e-08 32.6 0.3 1.7e-07 31.1 0.1 2.0 2 1 0 2 2 2 1 PUA domain FtsJ PF01728.19 OQR99521.1 - 4.8e-05 23.5 0.0 0.00016 21.8 0.0 1.8 1 1 0 1 1 1 1 FtsJ-like methyltransferase DUF938 PF06080.12 OQR99521.1 - 0.028 14.2 0.0 0.054 13.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF938) Ubie_methyltran PF01209.18 OQR99521.1 - 0.037 13.3 0.0 0.14 11.4 0.0 1.9 3 0 0 3 3 3 0 ubiE/COQ5 methyltransferase family Fibrillarin PF01269.17 OQR99521.1 - 0.071 12.2 0.0 0.13 11.4 0.0 1.4 1 0 0 1 1 1 0 Fibrillarin Methyltransf_31 PF13847.6 OQR99521.1 - 0.08 12.7 0.0 0.86 9.4 0.0 2.1 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.6 OQR99521.1 - 0.091 13.5 0.0 0.33 11.7 0.0 2.0 1 0 0 1 1 1 0 Methyltransferase domain Ribosomal_L6e PF01159.19 OQR99522.1 - 3.9e-39 133.6 3.8 6.3e-39 132.9 3.8 1.3 1 0 0 1 1 1 1 Ribosomal protein L6e P30 PF07390.11 OQR99522.1 - 0.0043 17.1 0.6 0.007 16.5 0.6 1.3 1 0 0 1 1 1 1 Mycoplasma P30 protein Copine PF07002.16 OQR99523.1 - 1.7e-164 544.2 0.2 5.6e-66 222.1 0.0 3.1 3 0 0 3 3 3 3 Copine vWA-TerF-like PF10138.9 OQR99523.1 - 4.4e-28 98.8 0.3 7e-11 42.6 0.1 3.2 3 0 0 3 3 3 3 vWA found in TerF C terminus VWA PF00092.28 OQR99523.1 - 1.2e-05 25.6 0.0 0.041 14.1 0.0 3.1 3 0 0 3 3 3 2 von Willebrand factor type A domain VWA_3 PF13768.6 OQR99523.1 - 7.4e-05 22.7 0.0 1 9.3 0.0 3.3 3 0 0 3 3 3 2 von Willebrand factor type A domain VWA_2 PF13519.6 OQR99523.1 - 0.0016 19.1 0.0 2 9.1 0.0 3.6 3 0 0 3 3 3 1 von Willebrand factor type A domain GAIN PF16489.5 OQR99523.1 - 0.039 13.4 0.0 30 3.9 0.0 3.3 3 0 0 3 3 3 0 GPCR-Autoproteolysis INducing (GAIN) domain DUF3502 PF12010.8 OQR99523.1 - 0.084 13.5 0.1 3.1 8.4 0.0 3.3 3 1 1 4 4 4 0 Domain of unknown function (DUF3502) Spore_YpjB PF09577.10 OQR99523.1 - 0.19 11.5 0.5 36 4.1 0.0 3.3 3 0 0 3 3 3 0 Sporulation protein YpjB (SpoYpjB) RRM_1 PF00076.22 OQR99524.1 - 1.4e-17 63.3 0.0 1.9e-17 62.8 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 OQR99524.1 - 0.18 11.7 0.0 0.28 11.1 0.0 1.3 1 0 0 1 1 1 0 Occluded RNA-recognition motif DAP_epimerase PF01678.19 OQR99524.1 - 0.18 12.0 0.0 0.26 11.4 0.0 1.2 1 0 0 1 1 1 0 Diaminopimelate epimerase Transformer PF06495.11 OQR99524.1 - 6.6 6.8 42.7 4.9 7.2 12.7 2.3 2 0 0 2 2 2 0 Fruit fly transformer protein DUF2196 PF09962.9 OQR99525.1 - 2e-25 88.6 0.9 2.8e-25 88.1 0.9 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2196) zf-RanBP PF00641.18 OQR99525.1 - 0.0014 17.9 6.1 0.0026 17.0 6.1 1.5 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others zf-Sec23_Sec24 PF04810.15 OQR99525.1 - 3.2 7.9 7.5 0.41 10.7 0.6 2.2 1 1 1 2 2 2 0 Sec23/Sec24 zinc finger 6PF2K PF01591.18 OQR99526.1 - 4.2e-65 219.2 0.0 6.3e-65 218.6 0.0 1.2 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 OQR99526.1 - 1e-24 87.3 0.0 2.9e-24 85.8 0.0 1.7 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.6 OQR99526.1 - 5.1e-05 23.5 0.0 0.0001 22.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain DUF2313 PF10076.9 OQR99526.1 - 0.0065 16.3 0.0 0.012 15.5 0.0 1.4 1 0 0 1 1 1 1 Uncharacterised protein conserved in bacteria (DUF2313) DUF1084 PF06454.11 OQR99527.1 - 7.6e-33 114.0 10.9 1.3e-32 113.3 10.9 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF1084) PX PF00787.24 OQR99529.1 - 2.5e-08 33.9 0.0 3.2e-08 33.5 0.0 1.1 1 0 0 1 1 1 1 PX domain DFP PF04127.15 OQR99536.1 - 4.5e-19 69.0 0.0 8.6e-11 42.0 0.0 2.6 2 1 0 2 2 2 2 DNA / pantothenate metabolism flavoprotein tRNA-synt_2 PF00152.20 OQR99537.1 - 6.9e-75 252.0 0.0 8.9e-75 251.7 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) WHEP-TRS PF00458.20 OQR99537.1 - 7.5e-13 48.4 1.1 2e-12 47.1 1.1 1.7 1 0 0 1 1 1 1 WHEP-TRS domain tRNA_anti-codon PF01336.25 OQR99537.1 - 2.6e-06 27.3 0.1 4.8e-06 26.5 0.1 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 OQR99537.1 - 0.005 16.4 0.2 1.3 8.5 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) Ank_2 PF12796.7 OQR99538.1 - 4.7e-27 94.4 3.1 1.5e-09 38.3 0.6 3.8 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.30 OQR99538.1 - 2.8e-25 87.6 8.5 4.1e-06 27.0 0.1 6.9 6 1 0 6 6 6 4 Ankyrin repeat Ank_4 PF13637.6 OQR99538.1 - 3.2e-25 88.2 0.8 4.8e-10 39.8 0.1 4.2 4 0 0 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQR99538.1 - 5.8e-17 60.1 1.4 0.0003 21.0 0.0 5.3 5 0 0 5 5 5 3 Ankyrin repeat Ank_5 PF13857.6 OQR99538.1 - 3.1e-15 56.0 5.6 0.0027 18.0 0.2 5.4 2 2 2 5 5 5 4 Ankyrin repeats (many copies) Mito_carr PF00153.27 OQR99546.1 - 6.3e-40 135.0 9.5 2.4e-17 62.6 0.4 3.5 3 0 0 3 3 3 3 Mitochondrial carrier protein Kelch_1 PF01344.25 OQR99546.1 - 1.7e-33 113.9 2.5 2.2e-07 30.3 0.0 6.7 6 0 0 6 6 6 5 Kelch motif Kelch_3 PF13415.6 OQR99546.1 - 4.7e-31 106.5 5.2 2.1e-07 31.0 0.0 6.7 6 0 0 6 6 6 6 Galactose oxidase, central domain GATase_3 PF07685.14 OQR99546.1 - 6.4e-31 107.5 0.0 1.2e-30 106.6 0.0 1.4 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain Kelch_5 PF13854.6 OQR99546.1 - 2.2e-27 94.5 0.0 0.00029 20.7 0.0 6.6 6 0 0 6 6 6 5 Kelch motif Kelch_6 PF13964.6 OQR99546.1 - 1.8e-25 88.3 8.5 7.3e-06 26.1 0.0 6.8 4 2 2 6 6 6 5 Kelch motif Kelch_4 PF13418.6 OQR99546.1 - 3.7e-22 78.1 10.6 3.3e-08 33.4 0.0 6.5 5 1 1 6 6 6 5 Galactose oxidase, central domain Kelch_2 PF07646.15 OQR99546.1 - 2.5e-18 65.3 13.7 0.0016 18.4 0.2 6.5 6 0 0 6 6 6 5 Kelch motif DUF5522 PF17653.1 OQR99546.1 - 3.8e-16 58.8 4.7 9.5e-16 57.5 4.7 1.8 1 0 0 1 1 1 1 Family of unknown function (DUF5522) AAA_26 PF13500.6 OQR99546.1 - 1e-09 38.5 0.0 1.8e-09 37.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain CbiA PF01656.23 OQR99546.1 - 4.5e-09 36.4 0.0 9.1e-09 35.4 0.0 1.5 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain Peripla_BP_2 PF01497.18 OQR99546.1 - 0.0017 18.0 0.0 0.0037 16.9 0.0 1.4 1 0 0 1 1 1 1 Periplasmic binding protein 2-Hacid_dh_C PF02826.19 OQR99548.1 - 4.1e-58 195.7 0.0 5.4e-58 195.3 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 OQR99548.1 - 3.5e-26 91.5 0.0 4.1e-26 91.2 0.0 1.0 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 OQR99548.1 - 0.0023 18.1 0.0 0.0048 17.1 0.0 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase CBP_BcsO PF17037.5 OQR99548.1 - 0.033 14.3 0.1 0.05 13.8 0.1 1.2 1 0 0 1 1 1 0 Cellulose biosynthesis protein BcsO SlyX PF04102.12 OQR99549.1 - 0.041 14.5 1.7 0.041 14.5 1.7 6.4 4 2 2 6 6 6 0 SlyX BRI3BP PF14965.6 OQR99549.1 - 0.98 8.9 3.7 10 5.6 0.7 3.3 2 1 1 3 3 3 0 Negative regulator of p53/TP53 GAS PF13851.6 OQR99549.1 - 1.7 7.9 50.7 0.01 15.2 21.2 3.5 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding DUF3698 PF12479.8 OQR99549.1 - 2 9.0 9.9 4.5 7.9 0.3 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3698) Glyco_transf_18 PF15024.6 OQR99549.1 - 6.1 5.3 13.1 0.034 12.7 3.3 2.0 2 1 1 3 3 3 0 Glycosyltransferase family 18 HOOK PF05622.12 OQR99549.1 - 6.5 4.8 54.7 0.0059 14.8 18.5 3.2 1 1 2 3 3 3 0 HOOK protein TMF_DNA_bd PF12329.8 OQR99549.1 - 8.5 6.5 45.9 0.2 11.7 1.7 5.9 2 2 4 7 7 7 0 TATA element modulatory factor 1 DNA binding Patatin PF01734.22 OQR99550.1 - 1.6e-24 87.3 0.2 3.2e-24 86.3 0.2 1.6 1 0 0 1 1 1 1 Patatin-like phospholipase cNMP_binding PF00027.29 OQR99550.1 - 1.1e-15 57.4 0.1 3e-06 27.2 0.0 3.5 3 0 0 3 3 3 3 Cyclic nucleotide-binding domain ECH_1 PF00378.20 OQR99551.1 - 1e-47 162.6 0.0 1.2e-47 162.3 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 OQR99551.1 - 5.6e-37 128.0 0.1 1.1e-31 110.6 0.0 2.0 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase SATase_N PF06426.14 OQR99552.1 - 0.1 13.0 1.1 0.47 10.9 0.3 2.4 2 1 1 3 3 3 0 Serine acetyltransferase, N-terminal Glyco_hydro_3 PF00933.21 OQR99553.1 - 9.6e-53 179.6 0.0 1.2e-52 179.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.22 OQR99553.1 - 2e-28 99.8 0.0 3.9e-28 98.8 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain MBF1 PF08523.10 OQR99554.1 - 3e-14 53.2 2.3 5.6e-14 52.4 2.3 1.5 1 0 0 1 1 1 1 Multiprotein bridging factor 1 HTH_3 PF01381.22 OQR99554.1 - 6.7e-13 48.5 0.1 1.2e-12 47.7 0.1 1.3 1 0 0 1 1 1 1 Helix-turn-helix HTH_31 PF13560.6 OQR99554.1 - 1.7e-05 25.1 0.0 3.5e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_19 PF12844.7 OQR99554.1 - 0.014 15.4 0.0 0.041 13.9 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain DUF5634 PF18681.1 OQR99554.1 - 0.084 13.2 0.0 0.19 12.1 0.0 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5634) DUF2852 PF11014.8 OQR99554.1 - 0.57 10.3 3.5 0.77 9.9 0.2 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2852) Hexapep PF00132.24 OQR99555.1 - 6.9e-28 95.3 33.4 1.5e-07 30.9 2.5 6.3 5 1 1 6 6 6 6 Bacterial transferase hexapeptide (six repeats) RRM_1 PF00076.22 OQR99555.1 - 4.8e-20 71.2 0.0 8.3e-20 70.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Hexapep_2 PF14602.6 OQR99555.1 - 2.4e-11 43.2 24.9 0.00068 19.3 3.7 5.5 4 1 0 4 4 4 3 Hexapeptide repeat of succinyl-transferase WW PF00397.26 OQR99555.1 - 6.6e-11 42.1 3.8 1.1e-10 41.3 3.8 1.4 1 0 0 1 1 1 1 WW domain Glyco_hyd_101C PF17451.2 OQR99555.1 - 0.011 16.1 0.1 0.025 14.8 0.1 1.6 1 0 0 1 1 1 0 Glycosyl hydrolase 101 beta sandwich domain RRM_5 PF13893.6 OQR99555.1 - 0.018 14.6 0.0 0.039 13.6 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Fucokinase PF07959.12 OQR99555.1 - 0.072 12.0 0.2 0.15 10.9 0.1 1.5 1 1 0 1 1 1 0 L-fucokinase BRAP2 PF07576.12 OQR99555.1 - 0.094 12.9 0.0 0.18 12.1 0.0 1.3 1 0 0 1 1 1 0 BRCA1-associated protein 2 Ago_PAZ PF18309.1 OQR99571.1 - 0.075 13.7 0.3 4.8 7.9 0.1 2.5 2 0 0 2 2 2 0 Argonaute PAZ domain WRC PF08879.10 OQR99571.1 - 0.12 12.1 1.9 8.1 6.2 0.2 2.7 2 0 0 2 2 2 0 WRC Cys_box PF17869.1 OQR99571.1 - 0.47 10.6 3.3 5.5 7.2 0.1 2.3 2 0 0 2 2 2 0 Anosmin cysteine rich domain zf-TAZ PF02135.16 OQR99572.1 - 0.00045 20.6 12.5 0.00087 19.7 12.5 1.5 1 1 0 1 1 1 1 TAZ zinc finger AZUL PF16558.5 OQR99572.1 - 0.83 9.9 7.1 3.4 8.0 0.8 2.3 2 0 0 2 2 2 0 Amino-terminal Zinc-binding domain of ubiquitin ligase E3A HhH-GPD PF00730.25 OQR99573.1 - 2.8e-21 76.0 0.0 5.1e-21 75.1 0.0 1.5 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein NUDIX_4 PF14815.6 OQR99573.1 - 4.5e-13 49.1 0.0 1.1e-12 47.9 0.0 1.7 1 0 0 1 1 1 1 NUDIX domain HHH PF00633.23 OQR99573.1 - 1.7e-09 37.1 0.0 1.7e-08 33.9 0.0 2.4 2 0 0 2 2 2 1 Helix-hairpin-helix motif HHH_5 PF14520.6 OQR99573.1 - 0.00021 21.8 0.0 0.022 15.4 0.0 2.4 1 1 1 2 2 2 1 Helix-hairpin-helix domain EndIII_4Fe-2S PF10576.9 OQR99573.1 - 0.0047 17.2 0.7 0.0047 17.2 0.7 1.8 2 0 0 2 2 2 1 Iron-sulfur binding domain of endonuclease III Chromo PF00385.24 OQR99573.1 - 0.056 13.4 1.1 0.28 11.1 0.3 2.4 2 0 0 2 2 2 0 Chromo (CHRromatin Organisation MOdifier) domain UPF0262 PF06793.12 OQR99573.1 - 0.08 13.0 0.0 0.14 12.2 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0262) Cdd1 PF11731.8 OQR99573.1 - 0.12 12.7 0.0 0.33 11.2 0.0 1.8 1 0 0 1 1 1 0 Pathogenicity locus HHH_2 PF12826.7 OQR99573.1 - 0.15 12.2 0.0 8.6 6.5 0.0 2.4 2 0 0 2 2 2 0 Helix-hairpin-helix motif Na_H_Exchanger PF00999.21 OQR99574.1 - 5e-60 203.3 41.2 6.1e-60 203.0 41.2 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family DSPn PF14671.6 OQR99575.1 - 5.7e-30 104.6 0.1 9.7e-29 100.6 0.2 2.3 2 0 0 2 2 2 1 Dual specificity protein phosphatase, N-terminal half DSPc PF00782.20 OQR99575.1 - 3.2e-14 52.9 0.0 7.9e-14 51.6 0.0 1.6 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 OQR99575.1 - 7.6e-06 25.7 0.0 1.5e-05 24.7 0.0 1.5 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 OQR99575.1 - 0.001 19.2 0.0 0.0019 18.4 0.0 1.4 1 0 0 1 1 1 1 Inositol hexakisphosphate Tox-REase-5 PF15648.6 OQR99575.1 - 0.024 15.1 0.0 0.05 14.1 0.0 1.5 1 0 0 1 1 1 0 Restriction endonuclease fold toxin 5 Peptidase_S8 PF00082.22 OQR99577.1 - 1.7e-39 135.9 3.6 1.7e-39 135.9 3.6 2.3 2 0 0 2 2 2 1 Subtilase family Ricin_B_lectin PF00652.22 OQR99577.1 - 2.6e-19 69.7 2.8 1.4e-09 38.3 0.2 2.4 2 0 0 2 2 2 2 Ricin-type beta-trefoil lectin domain NuA4 PF09340.10 OQR99577.1 - 4.2e-16 58.6 0.0 1.1e-15 57.3 0.0 1.7 1 0 0 1 1 1 1 Histone acetyltransferase subunit NuA4 RicinB_lectin_2 PF14200.6 OQR99577.1 - 3.9e-05 24.3 8.5 0.078 13.7 0.2 3.6 3 1 0 3 3 3 2 Ricin-type beta-trefoil lectin domain-like Nse5 PF08691.10 OQR99578.1 - 0.052 12.2 1.9 0.068 11.8 1.9 1.1 1 0 0 1 1 1 0 DNA repair proteins Nse5 and Nse6 MCR_C PF04609.12 OQR99578.1 - 0.057 12.5 0.2 0.065 12.3 0.2 1.2 1 0 0 1 1 1 0 Methyl-coenzyme M reductase operon protein C DUF4407 PF14362.6 OQR99578.1 - 0.54 9.6 5.0 0.67 9.3 5.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Fes1 PF08609.10 OQR99578.1 - 1.3 9.9 5.1 1.3 10.0 0.2 2.2 1 1 1 2 2 2 0 Nucleotide exchange factor Fes1 EF-hand_1 PF00036.32 OQR99579.1 - 1.9e-191 605.9 56.6 1.2e-06 27.7 0.0 35.5 36 0 0 36 36 36 31 EF hand EF-hand_7 PF13499.6 OQR99579.1 - 1.7e-168 547.4 60.6 1.3e-13 51.2 0.4 22.1 19 3 3 22 22 22 21 EF-hand domain pair EF-hand_6 PF13405.6 OQR99579.1 - 4.2e-165 521.9 64.6 4.3e-05 23.1 0.0 36.5 37 0 0 37 37 37 31 EF-hand domain EF-hand_5 PF13202.6 OQR99579.1 - 2.9e-144 462.8 69.0 4.5e-06 25.9 0.2 33.3 34 0 0 34 34 34 30 EF hand EF-hand_8 PF13833.6 OQR99579.1 - 4.6e-93 305.0 77.4 7.9e-05 22.4 0.1 34.9 31 7 6 37 37 37 27 EF-hand domain pair EF-hand_9 PF14658.6 OQR99579.1 - 2.9e-21 75.5 12.9 0.65 10.4 0.0 15.7 14 3 0 14 14 14 5 EF-hand domain EF-hand_2 PF09068.11 OQR99579.1 - 9.8e-18 64.5 0.0 2.8 8.1 0.0 12.2 12 3 0 12 12 12 4 EF hand SPARC_Ca_bdg PF10591.9 OQR99579.1 - 1.6e-17 63.8 22.7 2.6 8.4 0.0 20.3 18 5 4 22 22 22 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 OQR99579.1 - 2.2e-12 46.8 52.1 0.27 11.2 0.1 22.5 11 11 17 29 29 29 3 Cytoskeletal-regulatory complex EF hand Dockerin_1 PF00404.18 OQR99579.1 - 9.8e-08 32.1 27.1 12 6.2 0.1 15.9 15 7 4 19 19 19 1 Dockerin type I domain EF-hand_10 PF14788.6 OQR99579.1 - 1.8e-06 27.7 22.7 11 6.0 0.0 12.1 12 0 0 12 12 12 1 EF hand GH-E PF14410.6 OQR99579.1 - 0.0021 18.4 5.4 34 4.9 0.0 7.2 8 0 0 8 8 8 0 HNH/ENDO VII superfamily nuclease with conserved GHE residues CLZ PF16526.5 OQR99580.1 - 0.072 13.5 6.6 0.4 11.1 0.2 3.8 3 0 0 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels SHE3 PF17078.5 OQR99580.1 - 0.11 12.2 3.4 1.8 8.3 0.1 2.8 3 0 0 3 3 3 0 SWI5-dependent HO expression protein 3 Acyl-CoA_dh_2 PF08028.11 OQR99580.1 - 1.5 9.1 4.9 4.9 7.4 4.9 1.9 1 0 0 1 1 1 0 Acyl-CoA dehydrogenase, C-terminal domain Peptidase_S8 PF00082.22 OQR99581.1 - 1.2e-105 353.0 24.7 5e-36 124.5 3.7 4.7 4 1 0 4 4 4 3 Subtilase family Ricin_B_lectin PF00652.22 OQR99581.1 - 1.2e-35 122.6 24.8 8.4e-12 45.5 1.6 4.5 4 0 0 4 4 4 4 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.6 OQR99581.1 - 9e-09 35.9 12.2 0.00016 22.3 1.6 5.0 3 1 1 4 4 4 3 Ricin-type beta-trefoil lectin domain-like TFIIE_beta PF02186.15 OQR99581.1 - 0.00073 19.8 0.4 1.8 8.9 0.0 3.6 3 0 0 3 3 3 2 TFIIE beta subunit core domain CAMSAP_CKK PF08683.11 OQR99581.1 - 0.26 11.5 1.0 12 6.1 0.1 3.4 4 0 0 4 4 4 0 Microtubule-binding calmodulin-regulated spectrin-associated Tnp_P_element PF12017.8 OQR99582.1 - 0.048 13.1 0.0 0.059 12.8 0.0 1.1 1 0 0 1 1 1 0 Transposase protein zf-TAZ PF02135.16 OQR99597.1 - 1.5e-05 25.4 10.2 1.5e-05 25.4 10.2 3.5 3 0 0 3 3 3 2 TAZ zinc finger PWWP PF00855.17 OQR99597.1 - 0.00016 22.0 0.6 0.00048 20.5 0.6 1.7 1 0 0 1 1 1 1 PWWP domain VPS13_C PF16909.5 OQR99598.1 - 6.3e-60 202.0 14.8 6.3e-60 202.0 2.4 3.2 3 0 0 3 3 3 2 Vacuolar-sorting-associated 13 protein C-terminal VPS13 PF16908.5 OQR99598.1 - 5.3e-40 137.7 3.2 3.9e-39 134.9 2.6 3.0 2 1 0 2 2 2 1 Vacuolar sorting-associated protein 13, N-terminal SHR-BD PF06650.12 OQR99598.1 - 1.2e-33 116.7 0.2 1.7e-30 106.3 0.0 3.5 2 1 1 3 3 3 2 SHR-binding domain of vacuolar-sorting associated protein 13 Chorein_N PF12624.7 OQR99598.1 - 8.6e-24 83.9 0.2 6.2e-23 81.1 0.0 2.7 2 0 0 2 2 2 1 N-terminal region of Chorein or VPS13 ATG_C PF09333.11 OQR99598.1 - 4.7e-05 23.6 0.1 0.00019 21.7 0.1 2.0 2 0 0 2 2 2 1 Autophagy-related protein C terminal domain G8 PF10162.9 OQR99598.1 - 0.11 12.6 0.4 0.91 9.6 0.0 2.7 3 0 0 3 3 3 0 G8 domain Kinesin PF00225.23 OQR99600.1 - 5.1e-103 344.5 0.8 1.1e-102 343.4 0.8 1.6 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 OQR99600.1 - 6.4e-24 84.6 0.4 2.7e-23 82.6 0.0 2.3 2 0 0 2 2 2 1 Microtubule binding Lipoprot_C PF08794.10 OQR99600.1 - 0.019 15.0 0.2 0.079 13.0 0.1 2.0 2 0 0 2 2 2 0 Lipoprotein GNA1870 C terminal like DUF2165 PF09933.9 OQR99601.1 - 0.063 13.3 0.1 0.14 12.2 0.1 1.5 1 0 0 1 1 1 0 Predicted small integral membrane protein (DUF2165) Acetyltransf_16 PF05301.11 OQR99602.1 - 5.8e-42 143.4 0.6 6.8e-42 143.2 0.6 1.0 1 0 0 1 1 1 1 GNAT acetyltransferase, Mec-17 RRM_1 PF00076.22 OQR99604.1 - 1.9e-19 69.2 0.0 4.1e-09 36.1 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 OQR99604.1 - 1.8e-07 30.8 0.0 2.6e-05 23.8 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) T4_Rnl2_C PF18043.1 OQR99604.1 - 0.16 12.2 0.0 0.33 11.1 0.0 1.6 1 0 0 1 1 1 0 T4 RNA ligase 2 C-terminal Myc_target_1 PF15179.6 OQR99607.1 - 0.021 14.7 0.1 0.052 13.4 0.1 1.6 1 0 0 1 1 1 0 Myc target protein 1 Metallophos PF00149.28 OQR99607.1 - 0.064 13.8 0.0 0.2 12.1 0.1 1.8 2 0 0 2 2 2 0 Calcineurin-like phosphoesterase Transcrip_reg PF01709.20 OQR99608.1 - 2e-73 246.8 0.1 2.3e-73 246.5 0.1 1.0 1 0 0 1 1 1 1 Transcriptional regulator PhoD PF09423.10 OQR99610.1 - 4.6e-15 55.5 0.0 7.8e-14 51.4 0.0 2.2 1 1 0 1 1 1 1 PhoD-like phosphatase FeoB_associated PF12669.7 OQR99610.1 - 0.19 12.2 0.4 0.39 11.1 0.4 1.5 1 0 0 1 1 1 0 FeoB-associated Cys-rich membrane protein DNA_ligase_A_M PF01068.21 OQR99611.1 - 0.0031 17.2 0.1 0.0035 17.0 0.1 1.1 1 0 0 1 1 1 1 ATP dependent DNA ligase domain FAM199X PF15814.5 OQR99611.1 - 0.067 12.3 3.0 0.069 12.2 3.0 1.1 1 0 0 1 1 1 0 Protein family FAM199X DUF4485 PF14846.6 OQR99611.1 - 0.73 9.9 3.0 1.2 9.3 1.9 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4485) DUF4246 PF14033.6 OQR99613.1 - 7e-117 391.3 0.1 1.1e-116 390.7 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4246) Ank_2 PF12796.7 OQR99613.1 - 1.8e-35 121.3 23.8 1.3e-11 44.9 1.1 4.9 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQR99613.1 - 2.4e-25 88.6 9.3 6.7e-05 23.4 0.0 6.6 3 2 4 7 7 7 6 Ankyrin repeats (many copies) Ank PF00023.30 OQR99613.1 - 3.4e-25 87.3 14.2 0.00094 19.5 0.0 7.7 7 0 0 7 7 7 7 Ankyrin repeat Ank_3 PF13606.6 OQR99613.1 - 1.2e-22 77.6 9.7 0.016 15.7 0.0 8.4 8 0 0 8 8 8 6 Ankyrin repeat Ank_5 PF13857.6 OQR99613.1 - 3.8e-20 71.7 8.6 1.9e-05 24.8 0.1 5.6 2 2 2 5 5 5 5 Ankyrin repeats (many copies) 2OG-FeII_Oxy_5 PF13759.6 OQR99613.1 - 0.038 14.4 0.0 0.097 13.1 0.0 1.7 1 0 0 1 1 1 0 Putative 2OG-Fe(II) oxygenase zf_C2H2_ZHX PF18387.1 OQR99613.1 - 0.11 12.1 0.2 0.33 10.6 0.2 1.8 1 0 0 1 1 1 0 Zinc-fingers and homeoboxes C2H2 finger domain Na_Ca_ex PF01699.24 OQR99618.1 - 0.00097 19.1 0.0 0.00097 19.1 0.0 2.4 2 1 0 2 2 2 1 Sodium/calcium exchanger protein RGS PF00615.19 OQR99618.1 - 0.0038 17.5 0.1 0.072 13.4 0.1 2.2 1 1 0 1 1 1 1 Regulator of G protein signaling domain DUF2730 PF10805.8 OQR99618.1 - 0.1 12.7 0.0 0.24 11.5 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2730) Aminotran_1_2 PF00155.21 OQR99619.1 - 2.8e-22 79.4 0.0 7.1e-22 78.1 0.0 1.6 2 0 0 2 2 2 1 Aminotransferase class I and II Renin_r PF07850.14 OQR99619.1 - 0.0014 19.1 0.1 0.0035 17.9 0.1 1.7 1 0 0 1 1 1 1 Renin receptor-like protein Y_phosphatase2 PF03162.13 OQR99620.1 - 1.2e-43 148.6 0.0 1.5e-43 148.2 0.0 1.1 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.6 OQR99620.1 - 0.095 12.7 0.0 0.13 12.2 0.0 1.2 1 0 0 1 1 1 0 Tyrosine phosphatase family FYVE PF01363.21 OQR99621.1 - 0.0005 20.2 15.0 0.0016 18.5 14.9 1.8 1 1 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.16 OQR99621.1 - 0.039 14.2 8.6 0.077 13.2 8.6 1.4 1 0 0 1 1 1 0 FYVE-type zinc finger Methyltransf_11 PF08241.12 OQR99623.1 - 2e-07 31.6 0.0 2.9e-07 31.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OQR99623.1 - 5e-07 29.6 0.0 6.7e-07 29.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OQR99623.1 - 2.1e-05 25.1 0.0 4.7e-05 24.0 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 OQR99623.1 - 0.00034 20.0 0.2 0.00061 19.2 0.2 1.4 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 OQR99623.1 - 0.00051 20.7 0.0 0.0013 19.4 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 OQR99623.1 - 0.0064 16.3 0.0 0.0093 15.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain VPS9 PF02204.18 OQR99624.1 - 3.9e-16 59.2 0.2 5.4e-15 55.5 0.0 2.6 2 0 0 2 2 2 1 Vacuolar sorting protein 9 (VPS9) domain PX PF00787.24 OQR99624.1 - 0.006 16.6 0.0 0.034 14.1 0.0 2.2 2 0 0 2 2 2 1 PX domain Spidroin_N PF16763.5 OQR99624.1 - 0.058 13.4 0.3 0.23 11.5 0.3 2.0 1 0 0 1 1 1 0 Major ampullate spidroin 1, spider silk protein 1, N-term Amidase PF01425.21 OQR99638.1 - 4.5e-128 428.0 0.0 5.7e-128 427.7 0.0 1.1 1 0 0 1 1 1 1 Amidase Fe-ADH_2 PF13685.6 OQR99638.1 - 0.039 13.6 0.0 0.069 12.8 0.0 1.4 1 0 0 1 1 1 0 Iron-containing alcohol dehydrogenase FliD_N PF02465.18 OQR99639.1 - 0.3 11.8 2.5 0.26 12.0 0.9 1.6 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus Metallophos PF00149.28 OQR99640.1 - 3.2e-14 53.9 0.8 5.2e-14 53.2 0.8 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 OQR99640.1 - 0.0057 16.9 2.1 0.031 14.5 2.1 2.0 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Glyco_hydro_38N PF01074.22 OQR99640.1 - 0.044 13.1 0.0 0.077 12.4 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolases family 38 N-terminal domain Peptidase_U57 PF05582.12 OQR99640.1 - 0.18 11.0 0.1 0.29 10.4 0.1 1.2 1 0 0 1 1 1 0 YabG peptidase U57 RBFA PF02033.18 OQR99641.1 - 9.4e-13 48.5 0.1 2.4e-12 47.2 0.1 1.7 1 0 0 1 1 1 1 Ribosome-binding factor A DUF3668 PF12416.8 OQR99641.1 - 0.026 14.4 0.3 0.076 12.8 0.0 1.8 2 0 0 2 2 2 0 Cep120 protein DUF3122 PF11320.8 OQR99641.1 - 0.07 13.2 0.4 0.98 9.5 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3122) Cwf_Cwc_15 PF04889.12 OQR99641.1 - 0.26 11.0 15.4 0.4 10.4 15.4 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Gag_p19 PF02228.16 OQR99642.1 - 0.12 12.8 0.1 1.8 9.1 0.0 2.9 2 1 1 3 3 3 0 Major core protein p19 LINES_N PF14694.6 OQR99643.1 - 9.6e-11 41.7 3.5 2.1e-10 40.6 3.5 1.5 1 0 0 1 1 1 1 Lines N-terminus EF-hand_8 PF13833.6 OQR99644.1 - 1.6e-19 69.5 3.1 6.8e-05 22.6 0.0 4.5 4 0 0 4 4 4 4 EF-hand domain pair EF-hand_1 PF00036.32 OQR99644.1 - 3.2e-14 51.3 12.8 0.00023 20.5 0.1 6.0 6 0 0 6 6 6 4 EF hand EF-hand_6 PF13405.6 OQR99644.1 - 1e-13 50.0 16.2 0.012 15.5 1.5 6.6 7 0 0 7 7 7 4 EF-hand domain EF-hand_7 PF13499.6 OQR99644.1 - 1.1e-13 51.4 7.5 0.0053 17.2 1.1 5.5 4 2 1 5 5 5 4 EF-hand domain pair EF-hand_5 PF13202.6 OQR99644.1 - 2e-08 33.3 10.2 0.0019 17.6 0.2 4.3 4 0 0 4 4 4 3 EF hand EF-hand_4 PF12763.7 OQR99644.1 - 0.014 15.4 0.2 40 4.2 0.0 4.0 4 0 0 4 4 4 0 Cytoskeletal-regulatory complex EF hand Endonuc_Holl PF10107.9 OQR99644.1 - 0.52 10.2 6.6 4.6 7.1 1.3 3.6 3 1 0 3 3 3 0 Endonuclease related to archaeal Holliday junction resolvase DUF3682 PF12446.8 OQR99644.1 - 2.9 8.4 11.7 0.063 13.8 4.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3682) ABC_membrane PF00664.23 OQR99645.1 - 2.3e-49 168.5 16.8 3e-49 168.1 16.8 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 OQR99645.1 - 5.8e-34 117.5 0.0 1.1e-33 116.7 0.0 1.4 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 OQR99645.1 - 2.5e-06 27.1 0.7 4.1e-05 23.1 0.1 2.1 1 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 OQR99645.1 - 0.0021 18.3 0.1 0.013 15.8 0.1 2.2 1 1 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 OQR99645.1 - 0.0024 17.8 0.0 0.04 13.8 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase ABC_ATPase PF09818.9 OQR99645.1 - 0.0035 16.2 0.0 0.0061 15.4 0.0 1.3 1 0 0 1 1 1 1 Predicted ATPase of the ABC class AAA_16 PF13191.6 OQR99645.1 - 0.004 17.5 0.0 0.012 16.0 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain AAA PF00004.29 OQR99645.1 - 0.005 17.3 0.6 0.13 12.7 0.2 2.8 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) SbcCD_C PF13558.6 OQR99645.1 - 0.041 14.1 0.5 0.4 10.9 0.5 2.4 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_30 PF13604.6 OQR99645.1 - 0.045 13.5 1.1 0.25 11.1 0.2 2.7 2 1 0 2 2 2 0 AAA domain AAA_29 PF13555.6 OQR99645.1 - 0.046 13.5 0.0 0.12 12.1 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain APS_kinase PF01583.20 OQR99645.1 - 0.067 13.1 0.2 0.29 11.0 0.0 2.2 3 0 0 3 3 3 0 Adenylylsulphate kinase Rad17 PF03215.15 OQR99645.1 - 0.19 11.7 0.2 1.1 9.1 0.0 2.2 3 0 0 3 3 3 0 Rad17 P-loop domain LRR_6 PF13516.6 OQR99646.1 - 6.2e-09 35.2 13.6 0.044 13.8 0.0 5.6 6 0 0 6 6 6 4 Leucine Rich repeat LRR_4 PF12799.7 OQR99646.1 - 8.6e-09 35.5 7.2 0.017 15.5 0.0 4.9 3 1 1 5 5 5 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 OQR99646.1 - 1.2e-06 28.2 8.4 4.4 8.2 0.0 6.9 7 0 0 7 7 7 3 Leucine Rich Repeat LRR_8 PF13855.6 OQR99646.1 - 0.00013 21.7 12.5 0.0032 17.2 0.5 4.9 2 1 2 4 4 4 3 Leucine rich repeat DUF2550 PF10739.9 OQR99646.1 - 0.067 13.2 0.2 0.13 12.3 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2550) RNF111_N PF15303.6 OQR99657.1 - 2.8 7.6 10.1 15 5.2 0.1 4.2 4 0 0 4 4 4 0 E3 ubiquitin-protein ligase Arkadia N-terminus DUF3265 PF11665.8 OQR99657.1 - 3 8.1 24.6 8.7 6.7 0.2 7.4 8 0 0 8 8 8 0 Protein of unknown function (DUF3265) ssDBP PF17878.1 OQR99657.1 - 7.6 6.8 9.4 3.8 7.8 0.0 4.3 4 1 1 5 5 5 0 Single-stranded DNA-binding protein Phytochelatin PF05023.14 OQR99660.1 - 2.4e-15 56.4 0.1 1.1e-12 47.6 0.0 2.8 1 1 1 2 2 2 2 Phytochelatin synthase FHA PF00498.26 OQR99661.1 - 3.7e-12 46.4 0.0 8e-12 45.3 0.0 1.6 1 0 0 1 1 1 1 FHA domain NACHT PF05729.12 OQR99661.1 - 2.7e-07 30.6 0.0 7.3e-07 29.2 0.0 1.8 1 1 0 1 1 1 1 NACHT domain CHAT PF12770.7 OQR99661.1 - 3.6e-06 26.6 0.1 5.9e-06 25.9 0.1 1.3 1 0 0 1 1 1 1 CHAT domain NB-ARC PF00931.22 OQR99661.1 - 1.6e-05 24.3 0.0 3.4e-05 23.2 0.0 1.5 1 1 0 1 1 1 1 NB-ARC domain AAA_18 PF13238.6 OQR99661.1 - 0.00017 22.1 0.0 0.0023 18.5 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 OQR99661.1 - 0.00088 19.7 0.0 0.0017 18.8 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 OQR99661.1 - 0.0018 18.7 0.0 0.004 17.6 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_7 PF12775.7 OQR99661.1 - 0.017 14.6 0.0 0.035 13.6 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region RNA_helicase PF00910.22 OQR99661.1 - 0.019 15.4 0.1 0.11 12.9 0.0 2.4 3 0 0 3 3 2 0 RNA helicase AAA_22 PF13401.6 OQR99661.1 - 0.02 15.2 0.0 0.17 12.1 0.0 2.5 2 1 0 2 2 2 0 AAA domain FHA_2 PF17913.1 OQR99661.1 - 0.051 13.8 0.1 0.12 12.7 0.1 1.5 1 0 0 1 1 1 0 FHA domain SMC_N PF02463.19 OQR99661.1 - 0.11 11.9 0.0 0.54 9.7 0.0 1.9 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_14 PF13173.6 OQR99661.1 - 0.14 12.2 0.0 0.31 11.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 OQR99661.1 - 0.19 11.4 0.0 0.34 10.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain Abhydrolase_1 PF00561.20 OQR99662.1 - 2.8e-24 86.2 0.1 1.7e-22 80.3 0.1 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 OQR99662.1 - 4.8e-19 69.8 0.0 5.9e-19 69.5 0.0 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 OQR99662.1 - 4.7e-18 65.3 0.0 5.7e-18 65.0 0.0 1.1 1 0 0 1 1 1 1 Serine aminopeptidase, S33 DLH PF01738.18 OQR99662.1 - 6.3e-06 25.9 0.3 0.0016 18.0 0.2 2.3 2 0 0 2 2 2 2 Dienelactone hydrolase family LIDHydrolase PF10230.9 OQR99662.1 - 1.4e-05 24.8 0.1 0.0013 18.3 0.0 2.1 2 0 0 2 2 2 1 Lipid-droplet associated hydrolase BAAT_C PF08840.11 OQR99662.1 - 0.00015 21.8 0.1 0.00055 19.9 0.1 1.8 1 1 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_3 PF07859.13 OQR99662.1 - 0.00077 19.4 0.0 0.0011 18.8 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold PGAP1 PF07819.13 OQR99662.1 - 0.00083 19.1 0.0 0.028 14.1 0.0 2.0 2 0 0 2 2 2 1 PGAP1-like protein UPF0227 PF05728.12 OQR99662.1 - 0.0021 18.0 0.3 0.096 12.6 0.3 2.5 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0227) Abhydrolase_8 PF06259.12 OQR99662.1 - 0.0022 17.7 0.0 0.0037 16.9 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase Abhydrolase_5 PF12695.7 OQR99662.1 - 0.0054 16.5 0.0 3.2 7.5 0.0 2.3 2 0 0 2 2 2 2 Alpha/beta hydrolase family Peptidase_C80 PF11713.8 OQR99662.1 - 0.0074 16.5 0.0 0.017 15.4 0.0 1.5 1 0 0 1 1 1 1 Peptidase C80 family Peptidase_S15 PF02129.18 OQR99662.1 - 0.01 15.4 0.0 0.019 14.6 0.0 1.5 1 1 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) DUF1057 PF06342.12 OQR99662.1 - 0.043 12.8 0.0 0.08 12.0 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1057) Peptidase_S37 PF05576.11 OQR99662.1 - 0.085 11.5 0.0 0.11 11.1 0.0 1.1 1 0 0 1 1 1 0 PS-10 peptidase S37 Peptidase_S9 PF00326.21 OQR99662.1 - 0.11 12.0 0.1 1.8 8.0 0.0 2.2 2 0 0 2 2 2 0 Prolyl oligopeptidase family DUF2048 PF09752.9 OQR99662.1 - 0.21 10.7 0.6 0.46 9.5 0.6 1.7 1 1 0 1 1 1 0 Abhydrolase domain containing 18 TRPM_tetra PF16519.5 OQR99663.1 - 0.0066 16.5 0.0 0.046 13.8 0.0 2.1 1 1 0 1 1 1 1 Tetramerisation domain of TRPM RE_SacI PF09566.10 OQR99663.1 - 0.039 13.8 0.2 0.054 13.3 0.2 1.2 1 0 0 1 1 1 0 SacI restriction endonuclease MBT PF02820.18 OQR99663.1 - 0.15 12.4 0.0 0.56 10.6 0.0 1.9 1 1 0 1 1 1 0 mbt repeat Phytochelatin PF05023.14 OQR99664.1 - 1.6e-14 53.6 0.1 8.5e-11 41.5 0.1 2.9 1 1 1 2 2 2 2 Phytochelatin synthase Peptidase_C39_2 PF13529.6 OQR99664.1 - 0.007 16.9 0.2 4.3 7.9 0.0 2.3 2 0 0 2 2 2 2 Peptidase_C39 like family Mod_r PF07200.13 OQR99665.1 - 0.57 10.3 18.2 0.3 11.2 4.3 3.3 2 1 1 3 3 3 0 Modifier of rudimentary (Mod(r)) protein Amidase PF01425.21 OQR99666.1 - 1.9e-94 317.2 0.1 2.4e-94 316.8 0.1 1.1 1 0 0 1 1 1 1 Amidase TFB6 PF17110.5 OQR99667.1 - 0.62 9.8 4.6 1.1 9.0 4.6 1.4 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH DUF913 PF06025.12 OQR99667.1 - 3.2 6.6 5.9 4.8 6.1 5.9 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Arf PF00025.21 OQR99674.1 - 1.7e-30 105.7 0.0 3.2e-30 104.9 0.0 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.20 OQR99674.1 - 3.1e-09 36.5 0.0 3.3e-05 23.2 0.0 2.6 1 1 1 2 2 2 2 G-protein alpha subunit Roc PF08477.13 OQR99674.1 - 4.1e-07 30.2 0.0 1e-06 29.0 0.0 1.7 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 OQR99674.1 - 8.9e-06 25.3 0.0 1.6e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 OQR99674.1 - 0.0002 21.4 0.0 0.0005 20.1 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase Ras PF00071.22 OQR99674.1 - 0.00037 20.1 0.0 0.00069 19.2 0.0 1.4 1 0 0 1 1 1 1 Ras family zf-HC5HC2H PF13771.6 OQR99674.1 - 0.0061 16.8 1.1 0.015 15.5 1.1 1.6 1 0 0 1 1 1 1 PHD-like zinc-binding domain AAA_16 PF13191.6 OQR99674.1 - 0.0076 16.6 0.8 0.15 12.5 0.0 2.8 2 1 1 3 3 3 1 AAA ATPase domain Fae PF08714.11 OQR99674.1 - 0.024 14.6 0.2 0.052 13.5 0.2 1.5 1 0 0 1 1 1 0 Formaldehyde-activating enzyme (Fae) ABC_tran PF00005.27 OQR99674.1 - 0.029 14.9 2.2 0.04 14.4 0.0 2.3 3 0 0 3 3 3 0 ABC transporter Vmethyltransf PF01660.17 OQR99674.1 - 0.065 12.1 0.0 0.13 11.1 0.0 1.4 1 0 0 1 1 1 0 Viral methyltransferase NACHT PF05729.12 OQR99674.1 - 0.079 12.9 0.0 0.29 11.1 0.0 2.1 1 1 0 1 1 1 0 NACHT domain AAA_22 PF13401.6 OQR99674.1 - 0.089 13.1 0.0 0.51 10.6 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 OQR99674.1 - 0.1 12.4 0.1 0.24 11.2 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_18 PF13238.6 OQR99674.1 - 0.12 12.9 1.2 1.6 9.3 1.2 2.6 1 1 0 1 1 1 0 AAA domain IRK_C PF17655.1 OQR99689.1 - 1.1e-13 51.2 0.4 8.7e-13 48.2 0.1 2.2 2 0 0 2 2 2 1 Inward rectifier potassium channel C-terminal domain Ion_trans_2 PF07885.16 OQR99689.1 - 4.8e-07 29.6 21.9 0.00018 21.4 6.3 3.1 2 2 0 2 2 2 2 Ion channel IRK PF01007.20 OQR99689.1 - 0.00011 22.0 23.3 0.055 13.3 6.1 4.1 2 2 1 3 3 3 3 Inward rectifier potassium channel transmembrane domain DUF2207 PF09972.9 OQR99689.1 - 4.4 5.9 7.9 2.4 6.8 0.5 2.3 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) FYVE PF01363.21 OQR99691.1 - 5.3e-16 58.5 57.0 4.6e-06 26.7 13.8 3.8 3 0 0 3 3 3 3 FYVE zinc finger FYVE_2 PF02318.16 OQR99691.1 - 2e-08 34.4 41.8 0.00021 21.5 9.2 3.9 3 0 0 3 3 3 3 FYVE-type zinc finger zf-C2H2_jaz PF12171.8 OQR99691.1 - 0.24 11.7 4.4 3.2 8.2 0.5 3.1 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding eIF2_C PF09173.11 OQR99701.1 - 1.4e-11 44.4 0.1 3.1e-11 43.4 0.1 1.6 1 0 0 1 1 1 1 Initiation factor eIF2 gamma, C terminal GTP_EFTU_D2 PF03144.25 OQR99701.1 - 5.6e-06 26.6 0.0 1.3e-05 25.5 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 Tyr-DNA_phospho PF06087.12 OQR99715.1 - 3.1e-91 306.4 0.0 3.9e-91 306.1 0.0 1.1 1 0 0 1 1 1 1 Tyrosyl-DNA phosphodiesterase Man-6-P_recep PF02157.15 OQR99716.1 - 1.2 8.2 2.9 1.8 7.6 0.3 2.1 2 0 0 2 2 2 0 Mannose-6-phosphate receptor Aminotran_3 PF00202.21 OQR99718.1 - 1.6e-55 188.4 0.0 1.1e-54 185.6 0.0 2.0 1 1 0 1 1 1 1 Aminotransferase class-III AAA_26 PF13500.6 OQR99718.1 - 1.4e-22 80.5 0.0 4e-22 79.0 0.0 1.7 2 0 0 2 2 2 1 AAA domain Orn_Arg_deC_N PF02784.16 OQR99719.1 - 1e-42 146.2 0.0 2.2e-22 79.6 0.0 2.1 1 1 1 2 2 2 2 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.22 OQR99719.1 - 9.4e-07 29.0 0.0 1.7e-06 28.2 0.0 1.4 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain FH2 PF02181.23 OQR99720.1 - 2.4e-64 217.8 10.3 5.8e-64 216.5 10.3 1.7 1 0 0 1 1 1 1 Formin Homology 2 Domain CCDC53 PF10152.9 OQR99720.1 - 1.1e-17 64.9 81.7 5.1e-09 36.7 0.2 8.1 3 1 1 4 4 4 3 Subunit CCDC53 of WASH complex PTE PF02126.18 OQR99720.1 - 3.4e-11 43.1 0.0 5.9e-11 42.3 0.0 1.3 1 0 0 1 1 1 1 Phosphotriesterase family VATC PF18716.1 OQR99720.1 - 0.00011 22.0 0.4 0.0002 21.1 0.4 1.5 1 0 0 1 1 1 1 Vms1-associating treble clef domain MFS_1 PF07690.16 OQR99721.1 - 5.1e-52 176.9 38.7 9.1e-51 172.8 32.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 OQR99721.1 - 3.5e-06 26.2 5.0 3.5e-06 26.2 5.0 3.1 2 1 1 3 3 3 2 Sugar (and other) transporter MFS_4 PF06779.14 OQR99721.1 - 0.0004 19.8 26.4 0.028 13.7 26.4 2.1 1 1 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB Miga PF10265.9 OQR99756.1 - 0.037 13.0 0.0 0.042 12.8 0.0 1.0 1 0 0 1 1 1 0 Mitoguardin DUF4808 PF16066.5 OQR99756.1 - 0.072 13.6 0.4 0.13 12.8 0.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4808) DUF4381 PF14316.6 OQR99756.1 - 0.08 13.2 0.2 0.15 12.3 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) Bromo_coat PF01318.18 OQR99756.1 - 0.16 12.1 0.4 0.34 11.0 0.1 1.6 2 0 0 2 2 2 0 Bromovirus coat protein AA_permease_2 PF13520.6 OQR99757.1 - 1.2e-35 123.2 34.9 1.2e-35 123.2 34.9 1.4 1 1 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 OQR99757.1 - 1.9e-21 76.2 38.0 1.9e-21 76.2 38.0 2.4 1 1 2 3 3 3 1 Amino acid permease AA_permease_C PF13906.6 OQR99757.1 - 2.1e-14 53.3 5.3 2.1e-14 53.3 5.3 4.0 5 0 0 5 5 5 1 C-terminus of AA_permease DUF2637 PF10935.8 OQR99757.1 - 1.2 9.0 8.3 0.18 11.7 0.6 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF2637) DUF4713 PF15831.5 OQR99757.1 - 1.3 9.5 8.9 0.8 10.2 0.4 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4713) Thioredoxin PF00085.20 OQR99758.1 - 5.5e-40 135.5 0.1 2.2e-25 88.6 0.0 2.0 1 1 1 2 2 2 2 Thioredoxin Thioredoxin_8 PF13905.6 OQR99758.1 - 2.5e-08 34.1 0.0 6.4e-05 23.2 0.0 2.3 2 0 0 2 2 2 2 Thioredoxin-like Thioredoxin_2 PF13098.6 OQR99758.1 - 2.4e-07 31.2 0.2 0.0072 16.8 0.1 3.0 2 1 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_9 PF14595.6 OQR99758.1 - 3.3e-07 30.1 0.0 0.00011 22.0 0.0 2.1 1 1 1 2 2 2 2 Thioredoxin AhpC-TSA PF00578.21 OQR99758.1 - 1.4e-05 25.0 0.1 0.0047 16.9 0.1 2.2 1 1 0 2 2 2 2 AhpC/TSA family OST3_OST6 PF04756.13 OQR99758.1 - 2.9e-05 23.6 0.1 6.8e-05 22.4 0.1 1.6 1 1 1 2 2 2 1 OST3 / OST6 family, transporter family Glutaredoxin PF00462.24 OQR99758.1 - 0.00041 20.5 0.1 0.0037 17.5 0.0 2.4 2 0 0 2 2 2 1 Glutaredoxin Thioredoxin_7 PF13899.6 OQR99758.1 - 0.0023 18.1 0.1 0.15 12.2 0.1 2.5 1 1 0 2 2 2 1 Thioredoxin-like Redoxin PF08534.10 OQR99758.1 - 0.0029 17.3 1.1 1.9 8.2 0.0 2.4 1 1 1 2 2 2 2 Redoxin TraF PF13728.6 OQR99758.1 - 0.0057 16.5 0.1 1.4 8.7 0.1 2.1 1 1 1 2 2 2 2 F plasmid transfer operon protein Phage_holin_7_1 PF16081.5 OQR99759.1 - 5.7 7.1 11.9 4.1 7.6 9.2 2.0 1 1 1 2 2 2 0 Mycobacterial 2 TMS Phage Holin (M2 Hol) Family Bact_lectin PF18483.1 OQR99761.1 - 4.8e-16 59.4 0.0 2.3e-15 57.1 0.0 2.1 1 1 1 2 2 2 1 Bacterial lectin Lectin_legB PF00139.19 OQR99761.1 - 8e-13 48.5 0.3 6.3e-11 42.3 0.0 2.9 2 1 0 2 2 2 1 Legume lectin domain Lectin_leg-like PF03388.13 OQR99761.1 - 1.8e-05 24.2 0.0 0.048 13.0 0.0 2.9 2 1 0 2 2 2 2 Legume-like lectin family Fam20C PF06702.12 OQR99761.1 - 0.1 12.4 0.0 0.17 11.7 0.0 1.2 1 0 0 1 1 1 0 Golgi casein kinase, C-terminal, Fam20 Myotub-related PF06602.14 OQR99762.1 - 3.5e-122 407.7 0.0 6.8e-122 406.8 0.0 1.4 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain C2 PF00168.30 OQR99762.1 - 3e-16 59.6 0.0 1.1e-15 57.8 0.0 2.0 1 0 0 1 1 1 1 C2 domain FYVE PF01363.21 OQR99762.1 - 5.1e-15 55.4 14.1 5.1e-15 55.4 14.1 2.1 2 0 0 2 2 2 1 FYVE zinc finger Y_phosphatase3 PF13350.6 OQR99762.1 - 0.0013 18.8 0.0 0.0026 17.8 0.0 1.5 1 0 0 1 1 1 1 Tyrosine phosphatase family DSPc PF00782.20 OQR99762.1 - 0.06 13.2 0.0 0.15 11.8 0.0 1.6 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 OQR99762.1 - 0.1 12.2 0.3 0.2 11.2 0.0 1.5 2 0 0 2 2 2 0 Protein-tyrosine phosphatase Seryl_tRNA_N PF02403.22 OQR99762.1 - 0.1 12.8 0.3 0.26 11.5 0.3 1.6 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain Pox_A_type_inc PF04508.12 OQR99762.1 - 0.29 11.1 1.8 1.1 9.2 1.8 2.0 1 0 0 1 1 1 0 Viral A-type inclusion protein repeat UCH PF00443.29 OQR99764.1 - 1.3e-38 133.0 1.9 1.3e-38 133.0 1.9 1.6 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 OQR99764.1 - 2.1e-12 47.3 7.0 2.1e-12 47.3 7.0 3.0 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 OQR99764.1 - 9.9e-09 35.4 9.4 9.9e-09 35.4 9.4 2.8 4 0 0 4 4 4 1 Zn-finger in ubiquitin-hydrolases and other protein Cytomega_UL84 PF06284.11 OQR99764.1 - 0.017 13.6 0.4 0.026 13.0 0.4 1.2 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein BHD_2 PF10404.9 OQR99764.1 - 0.35 11.9 1.9 59 4.7 0.0 2.8 2 0 0 2 2 2 0 Rad4 beta-hairpin domain 2 RPAP2_Rtr1 PF04181.13 OQR99764.1 - 1.7 9.0 7.5 0.29 11.5 2.9 2.2 2 0 0 2 2 2 0 Rtr1/RPAP2 family EST1 PF10374.9 OQR99764.1 - 5.4 7.6 9.9 0.92 10.2 1.5 3.1 1 1 1 2 2 2 0 Telomerase activating protein Est1 RWP-RK PF02042.15 OQR99765.1 - 7.5e-19 67.5 0.1 1.3e-18 66.7 0.1 1.4 1 0 0 1 1 1 1 RWP-RK domain OSTbeta PF15048.6 OQR99771.1 - 0.069 13.3 0.1 0.15 12.2 0.1 1.5 1 0 0 1 1 1 0 Organic solute transporter subunit beta protein EphA2_TM PF14575.6 OQR99771.1 - 0.072 14.0 0.1 0.14 13.1 0.1 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain FAM110_C PF14160.6 OQR99772.1 - 0.0076 17.3 2.0 0.025 15.6 0.0 2.1 2 0 0 2 2 2 1 Centrosome-associated C terminus PTPA PF03095.15 OQR99774.1 - 1.2e-116 389.4 0.0 2.1e-116 388.6 0.0 1.4 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein Pkinase PF00069.25 OQR99774.1 - 7.3e-49 166.5 0.0 1.2e-48 165.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQR99774.1 - 1.5e-31 109.6 0.0 2.7e-31 108.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase SH3_1 PF00018.28 OQR99774.1 - 4e-26 90.4 4.4 2.9e-10 39.6 0.0 3.7 3 0 0 3 3 3 3 SH3 domain SH3_2 PF07653.17 OQR99774.1 - 9.9e-22 76.4 1.9 8.1e-09 35.0 0.0 3.8 3 0 0 3 3 3 2 Variant SH3 domain SH3_9 PF14604.6 OQR99774.1 - 4.7e-21 74.4 6.7 1.6e-08 34.2 0.2 4.0 4 0 0 4 4 4 3 Variant SH3 domain ACT_7 PF13840.6 OQR99774.1 - 2.2e-19 69.0 0.0 5.1e-19 67.8 0.0 1.6 1 0 0 1 1 1 1 ACT domain Pkinase_fungal PF17667.1 OQR99774.1 - 0.014 14.2 0.0 0.021 13.6 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Kinase-like PF14531.6 OQR99774.1 - 0.11 11.8 0.0 0.21 10.9 0.0 1.5 1 0 0 1 1 1 0 Kinase-like VirB7 PF17413.2 OQR99775.1 - 0.2 11.0 0.7 0.53 9.6 0.7 1.7 1 0 0 1 1 1 0 Outer membrane lipoprotein virB7 Ank_2 PF12796.7 OQR99776.1 - 1.3e-17 64.2 3.2 8e-06 26.4 0.1 4.1 2 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQR99776.1 - 5.1e-16 58.8 6.4 9.1e-06 26.1 0.7 5.5 3 2 0 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 OQR99776.1 - 3.6e-14 52.6 2.4 0.28 11.6 0.0 6.9 2 1 5 7 7 7 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQR99776.1 - 4.9e-09 35.7 4.6 1 10.1 0.1 6.6 6 1 1 7 7 7 2 Ankyrin repeat DUF5049 PF16468.5 OQR99776.1 - 0.00046 20.0 3.9 0.51 10.3 0.1 4.2 2 2 2 4 4 4 2 Domain of unknown function (DUF5049) Ank PF00023.30 OQR99776.1 - 0.076 13.5 3.9 2.1e+02 2.6 0.1 5.1 5 1 0 5 5 5 0 Ankyrin repeat ACT PF01842.25 OQR99777.1 - 0.068 13.0 0.0 0.27 11.0 0.0 2.0 2 0 0 2 2 2 0 ACT domain Senescence_reg PF04520.13 OQR99778.1 - 0.064 14.1 2.0 0.24 12.2 2.0 1.8 1 1 0 1 1 1 0 Senescence regulator CAF1A PF12253.8 OQR99778.1 - 0.091 12.9 0.4 0.14 12.4 0.4 1.3 1 0 0 1 1 1 0 Chromatin assembly factor 1 subunit A Abhydrolase_1 PF00561.20 OQR99779.1 - 3.6e-31 108.8 0.2 4.1e-15 56.1 0.0 3.9 2 2 1 3 3 3 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 OQR99779.1 - 1.7e-29 104.0 0.0 1.8e-14 54.9 0.0 2.1 2 0 0 2 2 2 2 Alpha/beta hydrolase family DUF1057 PF06342.12 OQR99779.1 - 4.7e-29 101.4 0.0 1.2e-13 50.8 0.0 2.3 1 1 0 2 2 2 2 Alpha/beta hydrolase of unknown function (DUF1057) Hydrolase_4 PF12146.8 OQR99779.1 - 1.8e-25 89.6 0.0 2.4e-12 46.7 0.0 2.5 2 1 0 2 2 2 2 Serine aminopeptidase, S33 Thioesterase PF00975.20 OQR99779.1 - 3.3e-09 37.2 0.0 0.0018 18.4 0.0 2.2 2 0 0 2 2 2 2 Thioesterase domain DUF676 PF05057.14 OQR99779.1 - 5.2e-07 29.4 0.0 0.0011 18.5 0.0 2.2 2 0 0 2 2 2 2 Putative serine esterase (DUF676) Ser_hydrolase PF06821.13 OQR99779.1 - 5.3e-07 29.7 0.1 0.089 12.6 0.0 3.8 4 0 0 4 4 4 2 Serine hydrolase Ndr PF03096.14 OQR99779.1 - 4.1e-06 25.7 0.0 0.074 11.7 0.0 2.4 2 0 0 2 2 2 2 Ndr family LIDHydrolase PF10230.9 OQR99779.1 - 4.5e-05 23.1 0.1 0.39 10.2 0.0 2.6 2 1 0 2 2 2 2 Lipid-droplet associated hydrolase FSH1 PF03959.13 OQR99779.1 - 5.7e-05 22.9 0.0 0.008 15.9 0.0 2.3 2 0 0 2 2 2 1 Serine hydrolase (FSH1) Abhydrolase_5 PF12695.7 OQR99779.1 - 5.8e-05 22.9 0.1 0.25 11.1 0.0 2.8 3 0 0 3 3 3 2 Alpha/beta hydrolase family Abhydrolase_2 PF02230.16 OQR99779.1 - 0.00067 19.5 0.1 1.9 8.2 0.0 4.5 5 0 0 5 5 5 1 Phospholipase/Carboxylesterase Lipase_3 PF01764.25 OQR99779.1 - 0.0031 17.4 0.2 2 8.3 0.1 2.4 2 0 0 2 2 2 2 Lipase (class 3) Chlorophyllase2 PF12740.7 OQR99779.1 - 0.0098 14.8 0.0 3.3 6.5 0.0 2.2 2 0 0 2 2 2 2 Chlorophyllase enzyme Gly_acyl_tr_C PF08444.10 OQR99779.1 - 0.021 15.0 0.0 4.8 7.5 0.0 2.8 3 0 0 3 3 3 0 Aralkyl acyl-CoA:amino acid N-acyltransferase, C-terminal region UPF0227 PF05728.12 OQR99779.1 - 0.034 14.1 0.4 4.7 7.1 0.1 3.0 2 1 0 2 2 2 0 Uncharacterised protein family (UPF0227) PGAP1 PF07819.13 OQR99779.1 - 0.037 13.7 0.1 15 5.2 0.1 3.0 3 0 0 3 3 3 0 PGAP1-like protein EHN PF06441.12 OQR99779.1 - 0.07 13.5 0.1 7.9 6.9 0.1 2.6 2 0 0 2 2 2 0 Epoxide hydrolase N terminus DUF915 PF06028.11 OQR99779.1 - 0.11 11.8 0.0 4.2 6.6 0.0 2.3 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) DUF2974 PF11187.8 OQR99779.1 - 0.13 11.8 0.0 6.2 6.3 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2974) PAF-AH_p_II PF03403.13 OQR99779.1 - 0.15 10.5 0.1 12 4.3 0.0 2.2 2 0 0 2 2 2 0 Platelet-activating factor acetylhydrolase, isoform II Dynein_C PF18199.1 OQR99780.1 - 1.3e-88 297.2 0.0 3.5e-88 295.8 0.0 1.8 1 0 0 1 1 1 1 Dynein heavy chain C-terminal domain AAA_9 PF12781.7 OQR99780.1 - 3.5e-84 281.3 5.8 3e-82 275.0 0.8 3.0 3 0 0 3 3 3 2 ATP-binding dynein motor region MT PF12777.7 OQR99780.1 - 4.4e-57 193.7 12.1 7.5e-57 192.9 12.1 1.4 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_lid_11 PF18198.1 OQR99780.1 - 9.1e-57 191.4 0.0 1.9e-56 190.4 0.0 1.6 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 OQR99780.1 - 1.2e-41 141.5 0.0 6.6e-41 139.1 0.0 2.3 2 0 0 2 2 2 1 Dynein heavy chain region D6 P-loop domain AAA_8 PF12780.7 OQR99780.1 - 1.5e-06 27.7 0.3 2.9e-06 26.8 0.3 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 Sec8_exocyst PF04048.14 OQR99780.1 - 0.011 15.6 0.5 3.5 7.5 0.1 3.4 2 0 0 2 2 2 0 Sec8 exocyst complex component specific domain Sec34 PF04136.15 OQR99780.1 - 0.012 15.5 0.3 0.012 15.5 0.3 2.5 2 0 0 2 2 2 0 Sec34-like family JHBP PF06585.11 OQR99780.1 - 0.014 14.6 0.0 0.025 13.7 0.0 1.3 1 0 0 1 1 1 0 Haemolymph juvenile hormone binding protein (JHBP) CspB_prodomain PF18425.1 OQR99780.1 - 0.073 13.1 0.9 0.23 11.5 0.9 1.9 1 0 0 1 1 1 0 Csp protease B prodomain Trans_reg_C PF00486.28 OQR99780.1 - 0.094 12.8 0.0 6.5 6.9 0.1 2.8 2 0 0 2 2 2 0 Transcriptional regulatory protein, C terminal Fez1 PF06818.15 OQR99780.1 - 0.66 10.4 15.4 0.19 12.1 0.4 3.4 3 0 0 3 3 3 0 Fez1 Spc7 PF08317.11 OQR99780.1 - 1 8.2 18.9 0.35 9.7 2.3 3.5 3 0 0 3 3 3 0 Spc7 kinetochore protein ERM PF00769.19 OQR99780.1 - 2.5 7.9 16.6 6.1 6.6 1.9 2.3 2 0 0 2 2 2 0 Ezrin/radixin/moesin family SKA2 PF16740.5 OQR99780.1 - 3.9 7.3 16.7 0.18 11.6 0.7 4.7 5 0 0 5 5 5 0 Spindle and kinetochore-associated protein 2 GvpK PF05121.12 OQR99781.1 - 0.018 15.0 0.3 0.018 15.0 0.3 1.6 2 0 0 2 2 2 0 Gas vesicle protein K RelB PF04221.12 OQR99781.1 - 0.061 13.3 0.3 0.13 12.2 0.3 1.5 1 0 0 1 1 1 0 RelB antitoxin Phage_Gp23 PF10669.9 OQR99781.1 - 0.063 13.6 0.0 0.13 12.6 0.0 1.4 1 0 0 1 1 1 0 Protein gp23 (Bacteriophage A118) TMEM51 PF15345.6 OQR99783.1 - 0.0057 16.5 0.1 0.0083 16.0 0.1 1.2 1 0 0 1 1 1 1 Transmembrane protein 51 EphA2_TM PF14575.6 OQR99783.1 - 0.0084 17.0 0.0 0.019 15.9 0.0 1.6 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain MAP17 PF15807.5 OQR99783.1 - 0.027 14.7 1.0 0.049 13.9 1.0 1.3 1 0 0 1 1 1 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 SID-1_RNA_chan PF13965.6 OQR99783.1 - 0.03 12.8 1.2 0.036 12.5 1.2 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 DUF4381 PF14316.6 OQR99783.1 - 0.047 13.9 0.0 0.081 13.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) Peptidase_S49_N PF08496.10 OQR99783.1 - 0.061 13.4 0.6 0.11 12.5 0.6 1.4 1 0 0 1 1 1 0 Peptidase family S49 N-terminal DUF2870 PF11069.8 OQR99783.1 - 0.13 12.7 1.1 0.24 11.8 1.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2870) FAM176 PF14851.6 OQR99783.1 - 0.17 11.5 2.0 0.16 11.6 0.7 1.6 2 0 0 2 2 2 0 FAM176 family ExoD PF06055.12 OQR99804.1 - 3.8 6.9 8.6 1.4 8.3 1.2 2.5 3 0 0 3 3 3 0 Exopolysaccharide synthesis, ExoD LRR_9 PF14580.6 OQR99805.1 - 1.7e-54 184.0 5.6 1.7e-44 151.4 4.1 2.4 2 0 0 2 2 2 2 Leucine-rich repeat SAP PF02037.27 OQR99805.1 - 5.2e-15 54.8 0.4 1.9e-14 53.0 0.4 2.1 1 0 0 1 1 1 1 SAP domain LRR_4 PF12799.7 OQR99805.1 - 3.4e-06 27.3 12.3 0.011 16.1 0.3 3.4 2 1 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 OQR99805.1 - 0.00018 21.2 8.1 0.0018 18.0 5.3 2.8 2 1 1 3 3 3 2 Leucine rich repeat HeH PF12949.7 OQR99805.1 - 0.018 14.8 0.1 0.079 12.7 0.1 2.2 1 1 0 1 1 1 0 HeH/LEM domain Anoctamin PF04547.12 OQR99806.1 - 4.6e-67 226.8 15.6 6.8e-67 226.2 15.6 1.2 1 0 0 1 1 1 1 Calcium-activated chloride channel C2 PF00168.30 OQR99806.1 - 1.4e-13 51.0 0.0 3.1e-13 49.9 0.0 1.6 1 0 0 1 1 1 1 C2 domain Mpv17_PMP22 PF04117.12 OQR99806.1 - 0.081 13.2 0.1 0.25 11.6 0.1 1.8 1 0 0 1 1 1 0 Mpv17 / PMP22 family His_Phos_1 PF00300.22 OQR99807.1 - 3.1e-28 98.8 0.0 1.1e-13 51.4 0.0 2.2 1 1 1 2 2 2 2 Histidine phosphatase superfamily (branch 1) Sulfate_transp PF00916.20 OQR99808.1 - 2.5e-13 49.6 20.6 3e-13 49.3 20.6 1.1 1 0 0 1 1 1 1 Sulfate permease family TMEM192 PF14802.6 OQR99809.1 - 0.76 8.8 4.0 0.81 8.7 0.1 2.3 2 1 0 2 2 2 0 TMEM192 family EF-hand_7 PF13499.6 OQR99810.1 - 6.1e-10 39.4 0.4 9.2e-10 38.8 0.4 1.2 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 OQR99810.1 - 7.6e-10 37.9 1.2 4.6e-05 23.0 0.1 2.5 2 1 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.32 OQR99810.1 - 7.6e-10 37.6 3.6 8.4e-06 25.0 0.2 3.1 2 1 1 3 3 3 2 EF hand EF-hand_5 PF13202.6 OQR99810.1 - 3.5e-08 32.6 2.8 8.3e-06 25.1 0.1 2.6 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.6 OQR99810.1 - 0.00049 19.9 0.7 0.84 9.5 0.1 2.3 2 0 0 2 2 2 2 EF-hand domain pair Caleosin PF05042.13 OQR99810.1 - 0.042 13.8 0.1 0.26 11.2 0.0 1.8 1 1 1 2 2 2 0 Caleosin related protein DUF3112 PF11309.8 OQR99811.1 - 0.086 12.3 8.7 0.15 11.5 0.9 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3112) Kei1 PF08552.11 OQR99811.1 - 0.48 10.3 8.3 0.042 13.7 1.0 2.6 2 1 0 2 2 2 0 Inositolphosphorylceramide synthase subunit Kei1 Inositol_P PF00459.25 OQR99820.1 - 4.4e-33 115.0 0.0 5.9e-33 114.5 0.0 1.1 1 0 0 1 1 1 1 Inositol monophosphatase family ECH_1 PF00378.20 OQR99821.1 - 6.1e-30 104.4 0.0 9.5e-30 103.7 0.0 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ACBP PF00887.19 OQR99821.1 - 6.3e-24 84.0 0.2 2.2e-23 82.3 0.0 1.9 2 0 0 2 2 2 1 Acyl CoA binding protein ECH_2 PF16113.5 OQR99821.1 - 1.4e-15 57.7 0.0 2.1e-15 57.1 0.0 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase SDF PF00375.18 OQR99822.1 - 9e-124 413.4 83.1 1.9e-67 228.0 33.4 3.3 2 2 0 2 2 2 2 Sodium:dicarboxylate symporter family DUF4501 PF14946.6 OQR99822.1 - 0.0074 16.4 3.1 0.3 11.1 0.1 3.1 3 0 0 3 3 3 2 Domain of unknown function (DUF4501) Acetyltransf_10 PF13673.7 OQR99826.1 - 1.2e-13 51.1 0.0 1.6e-13 50.7 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 OQR99826.1 - 1.6e-08 34.9 0.0 2.1e-08 34.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 OQR99826.1 - 0.00013 22.1 0.0 0.00016 21.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Lactamase_B_2 PF12706.7 OQR99827.1 - 1.1e-25 90.3 0.9 1.4e-25 90.1 0.9 1.1 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 OQR99827.1 - 3.9e-09 36.8 0.2 1.8e-08 34.6 0.2 1.9 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily Lactamase_B_3 PF13483.6 OQR99827.1 - 0.00019 21.3 0.1 0.00084 19.3 0.1 1.9 1 1 0 1 1 1 1 Beta-lactamase superfamily domain zf-LYAR PF08790.11 OQR99827.1 - 0.072 13.0 0.1 0.15 12.0 0.1 1.5 1 0 0 1 1 1 0 LYAR-type C2HC zinc finger EF-hand_1 PF00036.32 OQR99828.1 - 3e-14 51.4 3.9 1.9e-06 27.0 0.2 3.4 3 0 0 3 3 3 2 EF hand EF-hand_7 PF13499.6 OQR99828.1 - 1.1e-12 48.2 4.0 1.3e-12 48.0 1.4 2.6 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 OQR99828.1 - 5.5e-11 41.5 1.2 0.00012 21.7 0.0 3.5 3 0 0 3 3 3 2 EF-hand domain EF-hand_5 PF13202.6 OQR99828.1 - 6.2e-07 28.6 7.4 0.0014 18.1 0.1 3.5 4 0 0 4 4 4 2 EF hand EF-hand_8 PF13833.6 OQR99828.1 - 1.1e-06 28.4 1.6 0.011 15.6 0.2 2.7 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_9 PF14658.6 OQR99828.1 - 0.0091 16.3 0.0 0.024 14.9 0.0 1.7 1 0 0 1 1 1 1 EF-hand domain DUF3829 PF12889.7 OQR99828.1 - 0.025 14.1 2.9 0.057 12.9 2.9 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3829) TAFH PF07531.14 OQR99828.1 - 0.032 14.3 0.6 6.3 7.0 0.1 2.9 2 0 0 2 2 2 0 NHR1 homology to TAF FUSC PF04632.12 OQR99828.1 - 0.39 9.2 8.9 0.34 9.4 0.0 3.4 3 1 1 4 4 4 0 Fusaric acid resistance protein family Cob_adeno_trans PF01923.18 OQR99828.1 - 0.46 10.6 2.5 0.7 10.0 0.5 2.2 2 0 0 2 2 2 0 Cobalamin adenosyltransferase CAP_N PF01213.19 OQR99830.1 - 1.5e-62 211.9 0.1 1.5e-62 211.9 0.1 1.4 1 1 0 1 1 1 1 Adenylate cyclase associated (CAP) N terminal CAP_C PF08603.11 OQR99830.1 - 1.6e-50 170.8 3.7 2.3e-50 170.3 3.7 1.2 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal TBCC PF07986.12 OQR99830.1 - 3.5e-05 23.5 2.6 7.9e-05 22.4 2.6 1.6 1 1 0 1 1 1 1 Tubulin binding cofactor C RNA_lig_T4_1 PF09511.10 OQR99830.1 - 0.078 12.8 0.0 0.14 12.0 0.0 1.3 1 0 0 1 1 1 0 RNA ligase EMP70 PF02990.16 OQR99832.1 - 1.8e-201 670.4 8.2 2.3e-201 670.0 8.2 1.1 1 0 0 1 1 1 1 Endomembrane protein 70 Acetyltransf_10 PF13673.7 OQR99833.1 - 1.2e-18 67.2 0.0 1.4e-18 67.1 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 OQR99833.1 - 9e-12 45.3 0.0 1.1e-11 45.0 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 OQR99833.1 - 2.7e-10 40.5 0.0 3.2e-10 40.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 OQR99833.1 - 0.0001 22.4 0.0 0.00012 22.1 0.0 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 OQR99833.1 - 0.00018 21.5 0.1 0.0015 18.6 0.0 2.1 2 0 0 2 2 2 1 GCN5-related N-acetyl-transferase Acetyltransf_5 PF13444.6 OQR99833.1 - 0.00026 21.7 0.0 0.017 15.8 0.0 2.4 2 1 1 3 3 3 1 Acetyltransferase (GNAT) domain Transglut_core2 PF13369.6 OQR99833.1 - 0.034 13.7 0.0 0.046 13.3 0.0 1.3 1 0 0 1 1 1 0 Transglutaminase-like superfamily FR47 PF08445.10 OQR99833.1 - 0.073 13.0 0.0 0.19 11.7 0.0 1.7 1 1 0 1 1 1 0 FR47-like protein Acetyltransf_15 PF17013.5 OQR99833.1 - 0.2 11.1 0.0 0.87 9.0 0.0 2.0 1 1 0 1 1 1 0 Putative acetyl-transferase Pkinase PF00069.25 OQR99834.1 - 9.1e-167 553.0 0.0 4.9e-41 140.8 0.0 6.9 6 1 0 6 6 6 6 Protein kinase domain Pkinase_Tyr PF07714.17 OQR99834.1 - 4.4e-161 534.2 0.0 1.1e-42 146.2 0.0 4.3 4 0 0 4 4 4 4 Protein tyrosine kinase LRR_4 PF12799.7 OQR99834.1 - 8.5e-26 89.6 84.8 0.0016 18.8 1.1 15.9 11 5 3 15 15 15 11 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 OQR99834.1 - 7.3e-20 70.5 80.9 0.0011 18.7 7.3 12.4 6 4 5 14 14 14 10 Leucine rich repeat Pkinase_fungal PF17667.1 OQR99834.1 - 1.5e-10 40.5 0.0 0.4 9.4 0.0 4.2 4 0 0 4 4 4 4 Fungal protein kinase LRR_6 PF13516.6 OQR99834.1 - 1e-06 28.3 34.8 0.3 11.2 0.1 13.3 17 0 0 17 17 13 2 Leucine Rich repeat EphA2_TM PF14575.6 OQR99834.1 - 0.00023 22.0 4.5 10 7.1 0.1 5.3 6 0 0 6 6 6 1 Ephrin type-A receptor 2 transmembrane domain LRR_9 PF14580.6 OQR99834.1 - 0.00045 19.8 19.4 0.17 11.3 0.1 6.4 6 1 0 6 6 6 3 Leucine-rich repeat CODH_A_N PF18537.1 OQR99834.1 - 0.00052 20.0 0.0 24 5.0 0.0 5.0 5 0 0 5 5 4 0 Carbon monoxide dehydrogenase subunit alpha N-terminal domain Kinase-like PF14531.6 OQR99834.1 - 0.0059 16.0 0.0 20 4.4 0.0 4.4 4 0 0 4 4 4 0 Kinase-like TMEM154 PF15102.6 OQR99834.1 - 0.015 15.2 0.2 1 9.2 0.1 3.2 3 0 0 3 3 3 0 TMEM154 protein family Haspin_kinase PF12330.8 OQR99834.1 - 0.036 13.0 0.8 24 3.7 0.0 4.0 4 0 0 4 4 4 0 Haspin like kinase domain FtsZ_C PF12327.8 OQR99834.1 - 0.095 13.0 0.0 0.25 11.7 0.0 1.7 1 0 0 1 1 1 0 FtsZ family, C-terminal domain DUF4381 PF14316.6 OQR99834.1 - 0.32 11.2 6.3 4.6 7.5 0.0 3.7 4 0 0 4 4 3 0 Domain of unknown function (DUF4381) FixQ PF05545.11 OQR99834.1 - 0.4 10.7 2.9 4.5 7.3 0.0 3.2 3 0 0 3 3 3 0 Cbb3-type cytochrome oxidase component FixQ ATP-synt_I PF03899.15 OQR99834.1 - 3.7 8.0 6.9 7.7 6.9 0.0 3.8 4 0 0 4 4 4 0 ATP synthase I chain Lactamase_B_2 PF12706.7 OQR99835.1 - 7.1e-25 87.7 0.0 1.4e-24 86.8 0.0 1.4 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 OQR99835.1 - 1.5e-05 25.1 0.0 2.6e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_3 PF13483.6 OQR99835.1 - 0.00038 20.4 0.0 0.0012 18.8 0.0 1.7 1 1 0 1 1 1 1 Beta-lactamase superfamily domain XPA_N PF01286.18 OQR99835.1 - 0.53 10.4 4.5 19 5.4 0.0 2.7 2 0 0 2 2 2 0 XPA protein N-terminal zf-TAZ PF02135.16 OQR99836.1 - 3e-06 27.6 12.0 4.6e-06 27.0 12.0 1.3 1 0 0 1 1 1 1 TAZ zinc finger Pkinase_Tyr PF07714.17 OQR99837.1 - 1.6e-42 145.6 0.0 2.3e-42 145.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OQR99837.1 - 5.7e-39 134.1 0.0 2.6e-29 102.4 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain LRR_8 PF13855.6 OQR99837.1 - 0.0038 17.0 17.1 0.98 9.2 0.1 3.9 3 1 0 3 3 3 2 Leucine rich repeat ECSCR PF15820.5 OQR99837.1 - 0.025 14.4 0.0 0.055 13.3 0.0 1.5 1 0 0 1 1 1 0 Endothelial cell-specific chemotaxis regulator LRR_4 PF12799.7 OQR99837.1 - 0.025 15.0 20.8 1 9.9 0.8 4.7 2 2 2 4 4 4 0 Leucine Rich repeats (2 copies) Pkinase_fungal PF17667.1 OQR99837.1 - 0.038 12.8 0.0 0.056 12.2 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase LRR_9 PF14580.6 OQR99837.1 - 0.13 11.7 0.1 0.13 11.7 0.1 1.9 2 0 0 2 2 2 0 Leucine-rich repeat CLAMP PF14769.6 OQR99838.1 - 1.9e-23 82.8 0.9 2.8e-23 82.2 0.9 1.3 1 0 0 1 1 1 1 Flagellar C1a complex subunit C1a-32 CRR7 PF12095.8 OQR99838.1 - 0.069 13.6 0.2 1 9.8 0.0 2.2 2 0 0 2 2 2 0 Protein CHLORORESPIRATORY REDUCTION 7 Thiolase_N PF00108.23 OQR99839.1 - 2.3e-89 299.2 4.0 4.1e-89 298.4 2.6 1.9 2 0 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 OQR99839.1 - 1.8e-46 156.8 0.9 1.8e-45 153.5 0.3 2.5 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 OQR99839.1 - 1.2e-05 25.1 6.9 4.7e-05 23.1 1.1 3.5 2 1 2 4 4 4 1 Beta-ketoacyl synthase, N-terminal domain LEA_6 PF10714.9 OQR99839.1 - 0.07 13.2 0.2 0.31 11.1 0.0 2.2 2 0 0 2 2 2 0 Late embryogenesis abundant protein 18 Adap_comp_sub PF00928.21 OQR99840.1 - 5.3e-66 222.7 0.0 8.1e-66 222.1 0.0 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Bromodomain PF00439.25 OQR99840.1 - 1.6e-22 79.4 0.0 5.2e-22 77.7 0.1 1.9 2 0 0 2 2 2 1 Bromodomain COBRA1 PF06209.13 OQR99840.1 - 1e-13 51.0 2.8 2.1e-10 40.1 0.1 3.3 2 2 0 2 2 2 2 Cofactor of BRCA1 (COBRA1) Clat_adaptor_s PF01217.20 OQR99840.1 - 0.0041 17.1 0.0 0.0098 15.8 0.0 1.6 1 0 0 1 1 1 1 Clathrin adaptor complex small chain TniB PF05621.11 OQR99840.1 - 0.0041 16.5 0.2 0.048 13.1 0.1 2.2 2 0 0 2 2 2 1 Bacterial TniB protein FUSC_2 PF13515.6 OQR99841.1 - 0.51 10.5 16.0 1.2 9.3 10.0 2.9 2 0 0 2 2 2 0 Fusaric acid resistance protein-like YbgT_YccB PF08173.11 OQR99841.1 - 3.5 7.8 5.9 26 5.1 0.0 3.0 3 0 0 3 3 3 0 Membrane bound YbgT-like protein CCT PF06203.14 OQR99859.1 - 2.2e-14 53.2 15.4 2.3e-14 53.1 14.4 1.6 2 0 0 2 2 2 1 CCT motif RCC1 PF00415.18 OQR99860.1 - 1.6e-69 230.3 1.7 3e-14 53.4 0.3 7.4 7 0 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 OQR99860.1 - 2.5e-24 84.5 36.7 1.9e-07 30.7 2.9 9.1 8 1 0 8 8 8 6 Regulator of chromosome condensation (RCC1) repeat DnaJ PF00226.31 OQR99861.1 - 9.3e-24 83.3 4.4 2.6e-23 81.9 2.1 2.6 2 0 0 2 2 2 1 DnaJ domain TPR_1 PF00515.28 OQR99861.1 - 9.6e-24 82.2 9.4 0.0015 18.2 0.1 9.3 8 1 0 8 8 8 7 Tetratricopeptide repeat TPR_2 PF07719.17 OQR99861.1 - 1.4e-22 77.9 12.7 0.0032 17.5 0.2 9.9 8 2 0 8 8 8 6 Tetratricopeptide repeat TPR_11 PF13414.6 OQR99861.1 - 9.3e-22 76.4 1.0 0.032 13.9 0.2 8.5 6 2 2 8 8 8 6 TPR repeat TPR_8 PF13181.6 OQR99861.1 - 5.9e-15 54.2 11.8 0.031 14.5 0.1 9.4 8 2 1 9 9 8 4 Tetratricopeptide repeat TPR_19 PF14559.6 OQR99861.1 - 4e-14 52.9 10.3 4.2e-06 27.2 0.2 7.5 3 3 4 7 7 7 4 Tetratricopeptide repeat TPR_14 PF13428.6 OQR99861.1 - 2.4e-11 43.4 8.1 0.89 10.5 0.1 7.9 5 2 4 9 9 8 3 Tetratricopeptide repeat TPR_9 PF13371.6 OQR99861.1 - 4.2e-11 42.8 6.4 0.00095 19.3 0.0 5.9 6 1 1 7 7 6 2 Tetratricopeptide repeat TPR_16 PF13432.6 OQR99861.1 - 5.7e-10 39.7 17.8 0.14 12.8 0.1 7.9 7 2 1 8 8 8 4 Tetratricopeptide repeat TPR_7 PF13176.6 OQR99861.1 - 9.5e-10 37.8 3.6 0.13 12.3 0.1 6.1 5 1 0 5 5 5 3 Tetratricopeptide repeat TPR_12 PF13424.6 OQR99861.1 - 1.5e-05 25.2 24.1 3.4e-05 24.1 2.6 7.2 8 1 1 9 9 8 1 Tetratricopeptide repeat SHNi-TPR PF10516.9 OQR99861.1 - 0.0002 20.8 2.7 1.1 8.8 0.0 4.6 5 0 0 5 5 5 2 SHNi-TPR ANAPC3 PF12895.7 OQR99861.1 - 0.00025 21.2 12.7 0.0025 18.0 1.9 4.7 5 0 0 5 5 5 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 OQR99861.1 - 0.0019 18.7 5.0 5.5 7.8 0.0 6.9 8 1 0 8 8 6 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 OQR99861.1 - 0.0042 17.1 6.4 19 5.4 0.3 6.3 7 1 1 8 8 8 0 Fis1 C-terminal tetratricopeptide repeat DUF2379 PF09543.10 OQR99861.1 - 0.042 14.1 2.6 5.8 7.1 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2379) Stk19 PF10494.9 OQR99861.1 - 0.065 12.9 0.3 0.8 9.3 0.0 2.4 2 0 0 2 2 2 0 Serine-threonine protein kinase 19 Streptin-Immun PF11083.8 OQR99861.1 - 0.08 13.4 0.2 0.33 11.4 0.1 2.1 1 1 0 2 2 2 0 Lantibiotic streptin immunity protein TPR_17 PF13431.6 OQR99861.1 - 1.6 9.3 10.0 2.7 8.6 0.0 5.5 7 0 0 7 7 5 0 Tetratricopeptide repeat TPR_10 PF13374.6 OQR99861.1 - 3 7.8 14.2 7.2 6.6 0.1 5.7 8 0 0 8 8 7 0 Tetratricopeptide repeat Vps39_2 PF10367.9 OQR99862.1 - 1.6e-17 63.9 1.2 1.6e-17 63.9 1.2 2.1 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 2 Vps39_1 PF10366.9 OQR99862.1 - 3.3e-16 59.5 0.2 3.3e-16 59.5 0.2 2.8 3 0 0 3 3 3 1 Vacuolar sorting protein 39 domain 1 nos_propeller PF18764.1 OQR99863.1 - 0.14 12.1 0.0 1.6 8.7 0.0 2.5 2 0 0 2 2 2 0 Nitrous oxide reductase propeller repeat Peptidase_S49_N PF08496.10 OQR99863.1 - 0.82 9.7 4.0 1.3 9.1 4.0 1.3 1 0 0 1 1 1 0 Peptidase family S49 N-terminal DSPc PF00782.20 OQR99864.1 - 9.7e-19 67.5 0.0 1.2e-18 67.2 0.0 1.1 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 OQR99864.1 - 0.00028 20.5 0.0 0.00037 20.1 0.0 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase CDKN3 PF05706.12 OQR99864.1 - 0.0016 18.2 0.0 0.0026 17.5 0.0 1.4 1 0 0 1 1 1 1 Cyclin-dependent kinase inhibitor 3 (CDKN3) PTPlike_phytase PF14566.6 OQR99864.1 - 0.015 15.4 0.0 0.024 14.8 0.0 1.3 1 0 0 1 1 1 0 Inositol hexakisphosphate DUF442 PF04273.13 OQR99864.1 - 0.018 15.1 0.0 0.045 13.8 0.0 1.6 1 1 0 1 1 1 0 Putative phosphatase (DUF442) Init_tRNA_PT PF04179.12 OQR99864.1 - 0.021 15.1 0.0 0.033 14.5 0.0 1.2 1 0 0 1 1 1 0 Rit1 DUSP-like domain WW PF00397.26 OQR99865.1 - 1.1e-10 41.3 4.2 2.3e-10 40.4 4.2 1.5 1 0 0 1 1 1 1 WW domain WH2 PF02205.20 OQR99865.1 - 1.4e-08 34.3 5.9 5.3e-08 32.5 2.0 3.1 3 0 0 3 3 3 1 WH2 motif DUF1631 PF07793.11 OQR99865.1 - 0.89 7.9 6.6 1.1 7.6 6.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1631) Activator_LAG-3 PF11498.8 OQR99866.1 - 0.13 11.3 18.3 0.14 11.1 18.3 1.1 1 0 0 1 1 1 0 Transcriptional activator LAG-3 Connexin40_C PF16791.5 OQR99866.1 - 2.2 9.6 8.0 3.1 9.1 8.0 1.2 1 0 0 1 1 1 0 Connexin 40 C-terminal domain PolyA_pol PF01743.20 OQR99866.1 - 2.8 8.4 5.6 6.4 7.2 5.6 1.6 1 1 0 1 1 1 0 Poly A polymerase head domain Glyco_transf_28 PF03033.20 OQR99867.1 - 3.3e-30 105.0 0.0 4.1e-18 65.8 0.0 2.7 2 0 0 2 2 2 2 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.18 OQR99867.1 - 3.3e-07 29.5 0.0 7.4e-07 28.3 0.0 1.5 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase ATG_C PF09333.11 OQR99867.1 - 0.00011 22.4 0.0 0.0033 17.8 0.0 3.2 4 0 0 4 4 4 1 Autophagy-related protein C terminal domain DnaJ PF00226.31 OQR99868.1 - 2e-20 72.7 2.1 5.7e-20 71.2 2.1 1.9 1 0 0 1 1 1 1 DnaJ domain TPR_1 PF00515.28 OQR99868.1 - 4.7e-14 51.5 26.2 2.5e-06 27.1 0.9 7.2 8 0 0 8 8 7 4 Tetratricopeptide repeat TPR_2 PF07719.17 OQR99868.1 - 2.4e-11 42.9 27.2 0.0031 17.5 0.5 8.2 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_19 PF14559.6 OQR99868.1 - 2.7e-09 37.4 17.7 0.00077 19.9 1.2 5.7 4 2 2 6 6 6 3 Tetratricopeptide repeat TPR_8 PF13181.6 OQR99868.1 - 0.00036 20.5 12.8 0.95 9.8 0.2 6.1 7 0 0 7 7 6 2 Tetratricopeptide repeat ANAPC3 PF12895.7 OQR99868.1 - 0.00045 20.4 20.5 0.033 14.4 6.7 3.8 3 0 0 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.6 OQR99868.1 - 0.0012 19.5 17.6 0.09 13.6 0.5 6.4 5 1 2 7 7 7 1 Tetratricopeptide repeat TPR_16 PF13432.6 OQR99868.1 - 0.0018 18.9 16.6 0.004 17.8 0.9 4.2 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_9 PF13371.6 OQR99868.1 - 0.014 15.6 7.7 0.063 13.4 0.4 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_17 PF13431.6 OQR99868.1 - 0.041 14.3 12.5 3.1 8.4 0.7 4.8 4 0 0 4 4 4 0 Tetratricopeptide repeat Phage_int_SAM_5 PF13102.6 OQR99868.1 - 0.044 14.1 0.0 0.18 12.2 0.0 2.0 1 0 0 1 1 1 0 Phage integrase SAM-like domain NYD-SP12_N PF15015.6 OQR99868.1 - 0.15 10.4 8.1 0.38 9.1 0.2 3.1 3 0 0 3 3 3 0 Spermatogenesis-associated, N-terminal TPR_6 PF13174.6 OQR99868.1 - 0.16 12.7 12.5 0.27 12.0 0.8 5.4 7 0 0 7 7 5 0 Tetratricopeptide repeat Flavi_propep PF01570.17 OQR99868.1 - 0.19 11.7 1.3 0.44 10.5 1.3 1.6 1 0 0 1 1 1 0 Flavivirus polyprotein propeptide TPR_12 PF13424.6 OQR99868.1 - 1.3 9.4 23.3 0.034 14.4 2.9 5.0 6 1 0 6 6 6 0 Tetratricopeptide repeat PHC2_SAM_assoc PF16616.5 OQR99869.1 - 1.1 10.1 9.0 0.5 11.2 0.8 2.3 2 0 0 2 2 2 0 Unstructured region on Polyhomeotic-like protein 1 and 2 FlxA PF14282.6 OQR99869.1 - 4.1 7.5 13.9 0.081 12.9 6.7 1.8 2 0 0 2 2 2 0 FlxA-like protein Radial_spoke PF04712.12 OQR99877.1 - 3.7e-87 293.3 0.0 7.6e-50 170.3 0.1 2.1 1 1 1 2 2 2 2 Radial spokehead-like protein FYVE PF01363.21 OQR99878.1 - 5.7e-11 42.4 11.4 1.2e-10 41.4 11.4 1.6 1 0 0 1 1 1 1 FYVE zinc finger Exo_endo_phos_2 PF14529.6 OQR99878.1 - 0.016 15.0 0.1 0.13 12.1 0.0 2.6 3 0 0 3 3 3 0 Endonuclease-reverse transcriptase FYVE_2 PF02318.16 OQR99878.1 - 0.021 15.0 8.3 0.057 13.6 8.3 1.6 1 0 0 1 1 1 0 FYVE-type zinc finger C1_2 PF03107.16 OQR99878.1 - 0.065 13.6 4.1 0.16 12.3 4.1 1.7 1 0 0 1 1 1 0 C1 domain Siva PF05458.12 OQR99878.1 - 0.53 9.9 7.0 1.1 8.9 7.0 1.5 1 0 0 1 1 1 0 Cd27 binding protein (Siva) zf-RING_5 PF14634.6 OQR99878.1 - 1.8 8.6 9.5 3.2 7.8 9.5 1.5 1 0 0 1 1 1 0 zinc-RING finger domain E1-E2_ATPase PF00122.20 OQR99879.1 - 1.1e-44 152.1 1.6 1.1e-44 152.1 1.6 2.6 3 0 0 3 3 3 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 OQR99879.1 - 4.9e-33 114.4 23.4 1.3e-17 64.2 0.1 3.6 4 0 0 4 4 4 2 Cation transporting ATPase, C-terminus Cation_ATPase PF13246.6 OQR99879.1 - 1.6e-23 82.6 0.0 3.9e-23 81.4 0.0 1.7 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 OQR99879.1 - 5.3e-19 69.3 0.0 9.7e-09 35.8 0.0 3.4 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 OQR99879.1 - 1.5e-13 50.2 0.0 3.5e-13 49.0 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 OQR99879.1 - 4.9e-06 26.5 0.2 0.001 18.8 0.4 2.5 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF2157 PF09925.9 OQR99879.1 - 0.0073 16.1 1.8 5.2 6.8 0.0 2.7 2 0 0 2 2 2 2 Predicted membrane protein (DUF2157) Wzy_C PF04932.15 OQR99879.1 - 0.11 12.2 1.9 2.7 7.6 0.0 2.6 2 0 0 2 2 2 0 O-Antigen ligase Peptidase_M3 PF01432.20 OQR99880.1 - 1.7e-114 383.6 0.3 2.5e-114 383.1 0.3 1.3 1 0 0 1 1 1 1 Peptidase family M3 Bromo_TP PF07524.13 OQR99881.1 - 4e-15 55.6 0.0 1.1e-14 54.1 0.0 1.7 1 1 1 2 2 2 1 Bromodomain associated TAF8_C PF10406.9 OQR99881.1 - 1.7e-09 38.0 2.0 1.7e-09 38.0 2.0 2.4 2 0 0 2 2 2 1 Transcription factor TFIID complex subunit 8 C-term CENP-T_C PF15511.6 OQR99881.1 - 0.00077 19.6 0.0 0.0018 18.4 0.0 1.6 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TFIID-31kDa PF02291.15 OQR99881.1 - 0.0014 18.7 0.0 0.0026 17.8 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit CBFD_NFYB_HMF PF00808.23 OQR99881.1 - 0.0065 16.7 0.1 0.048 13.9 0.0 2.1 1 1 1 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 OQR99881.1 - 0.0088 16.4 0.7 0.016 15.6 0.1 1.8 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 OQR99881.1 - 0.019 15.3 0.0 0.045 14.1 0.0 1.7 1 0 0 1 1 1 0 CENP-S protein HAMP_N3 PF18575.1 OQR99881.1 - 0.11 12.1 0.5 0.3 10.7 0.5 1.7 1 0 0 1 1 1 0 HAMP N-terminal domain 3 OB_NTP_bind PF07717.16 OQR99882.1 - 7.1e-21 74.4 0.1 2.3e-20 72.7 0.0 2.0 2 0 0 2 2 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.23 OQR99882.1 - 2.7e-16 59.8 2.6 8.9e-16 58.1 0.0 2.7 2 0 0 2 2 2 1 Helicase associated domain (HA2) Helicase_C PF00271.31 OQR99882.1 - 2.3e-13 50.4 0.0 8e-13 48.7 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 OQR99882.1 - 2.7e-09 37.1 0.1 5.6e-09 36.0 0.1 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase RWD PF05773.22 OQR99882.1 - 8.9e-09 35.6 0.2 2.7e-08 34.1 0.2 1.9 1 0 0 1 1 1 1 RWD domain dsrm PF00035.26 OQR99882.1 - 5.6e-05 23.8 0.0 0.00018 22.1 0.0 2.0 1 0 0 1 1 1 1 Double-stranded RNA binding motif T2SSE PF00437.20 OQR99882.1 - 0.00056 19.1 0.0 0.0012 18.0 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein ResIII PF04851.15 OQR99882.1 - 0.00059 19.9 1.5 0.0032 17.5 0.0 3.0 2 2 1 3 3 3 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 OQR99882.1 - 0.0025 18.1 0.0 0.0071 16.7 0.0 1.8 1 0 0 1 1 1 1 AAA domain DND1_DSRM PF14709.7 OQR99882.1 - 0.003 17.8 0.0 0.0083 16.4 0.0 1.8 1 0 0 1 1 1 1 double strand RNA binding domain from DEAD END PROTEIN 1 AAA_23 PF13476.6 OQR99882.1 - 0.0031 18.0 1.7 0.069 13.6 0.0 3.0 3 0 0 3 3 2 1 AAA domain AAA_22 PF13401.6 OQR99882.1 - 0.0074 16.6 0.9 0.033 14.5 0.1 2.5 2 0 0 2 2 2 1 AAA domain Rad17 PF03215.15 OQR99882.1 - 0.015 15.3 1.7 0.09 12.7 1.1 2.4 2 1 0 2 2 2 0 Rad17 P-loop domain ATPase PF06745.13 OQR99882.1 - 0.032 13.6 0.0 0.073 12.4 0.0 1.5 1 0 0 1 1 1 0 KaiC AAA_29 PF13555.6 OQR99882.1 - 0.067 12.9 0.1 7.1 6.5 0.0 2.6 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_14 PF13173.6 OQR99882.1 - 0.098 12.7 0.0 0.57 10.2 0.0 2.4 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.6 OQR99882.1 - 0.12 12.7 2.5 1.2 9.5 0.2 3.2 3 1 0 3 3 3 0 AAA ATPase domain GST_N_2 PF13409.6 OQR99907.1 - 2.9e-14 53.1 0.0 5.8e-13 49.0 0.0 2.6 3 0 0 3 3 3 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 OQR99907.1 - 6.7e-13 48.8 0.0 1.4e-12 47.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 OQR99907.1 - 1e-12 48.3 0.0 2.4e-12 47.1 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 OQR99907.1 - 0.0075 16.5 0.0 0.016 15.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 OQR99907.1 - 0.023 14.9 0.0 0.046 13.9 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain PCRF PF03462.18 OQR99908.1 - 6.5e-58 195.8 0.5 1.3e-57 194.9 0.0 1.7 2 0 0 2 2 2 1 PCRF domain RF-1 PF00472.20 OQR99908.1 - 1.7e-37 127.9 1.9 1.7e-37 127.9 1.9 1.9 2 0 0 2 2 2 1 RF-1 domain Suc_Fer-like PF06999.12 OQR99909.1 - 4.6e-31 108.2 0.1 5.3e-31 108.0 0.1 1.0 1 0 0 1 1 1 1 Sucrase/ferredoxin-like Phage_hub_GP28 PF11110.8 OQR99909.1 - 0.026 14.4 0.0 0.065 13.1 0.0 1.6 2 0 0 2 2 2 0 Baseplate hub distal subunit TPX2 PF06886.11 OQR99917.1 - 0.11 12.7 0.9 0.17 12.1 0.9 1.3 1 0 0 1 1 1 0 Targeting protein for Xklp2 (TPX2) UCH PF00443.29 OQR99918.1 - 1.7e-74 250.5 1.9 2.1e-74 250.3 1.9 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 OQR99918.1 - 4.1e-16 59.5 3.4 3.4e-07 30.2 0.2 2.6 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.12 OQR99918.1 - 2.2e-12 47.4 0.0 6.4e-12 45.9 0.0 1.8 1 0 0 1 1 1 1 DUSP domain zf-MYND PF01753.18 OQR99918.1 - 7.7e-08 32.3 14.4 7.7e-08 32.3 14.4 3.3 3 0 0 3 3 3 1 MYND finger USP7_C2 PF14533.6 OQR99918.1 - 0.0009 19.0 0.1 0.002 17.9 0.0 1.6 2 0 0 2 2 2 1 Ubiquitin-specific protease C-terminal zf-C6H2 PF15801.5 OQR99918.1 - 3.6 8.0 21.5 0.3 11.4 7.1 4.2 4 0 0 4 4 4 0 zf-MYND-like zinc finger, mRNA-binding Sec34 PF04136.15 OQR99920.1 - 0.039 13.8 2.4 0.072 13.0 2.4 1.5 1 0 0 1 1 1 0 Sec34-like family Baculo_PEP_C PF04513.12 OQR99920.1 - 0.11 12.6 2.2 0.56 10.2 0.7 2.1 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF4381 PF14316.6 OQR99920.1 - 0.26 11.5 1.3 0.5 10.6 0.9 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4381) DASH_Dad2 PF08654.10 OQR99920.1 - 1.6 9.2 6.4 0.22 12.0 1.5 2.1 2 1 1 3 3 3 0 DASH complex subunit Dad2 S1-P1_nuclease PF02265.16 OQR99921.1 - 3.7e-36 125.2 0.0 7.2e-36 124.3 0.0 1.5 1 0 0 1 1 1 1 S1/P1 Nuclease TPR_12 PF13424.6 OQR99921.1 - 6.5e-17 61.6 27.8 1.3e-06 28.6 1.8 4.0 2 1 3 5 5 5 5 Tetratricopeptide repeat TPR_1 PF00515.28 OQR99921.1 - 9.5e-15 53.7 6.1 0.00035 20.3 0.0 4.7 5 0 0 5 5 4 3 Tetratricopeptide repeat TPR_2 PF07719.17 OQR99921.1 - 1e-14 53.4 6.3 0.00014 21.7 0.7 4.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.6 OQR99921.1 - 1.8e-13 49.5 9.4 8.5e-05 22.3 0.0 5.3 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_8 PF13181.6 OQR99921.1 - 1e-11 44.0 3.6 0.006 16.7 0.5 4.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_10 PF13374.6 OQR99921.1 - 4.3e-06 26.4 6.8 0.27 11.1 0.1 4.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 OQR99921.1 - 2.4e-05 24.8 7.5 0.13 13.1 0.0 4.6 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_MalT PF17874.1 OQR99921.1 - 3.8e-05 23.2 7.1 0.00014 21.4 6.8 1.8 1 1 0 1 1 1 1 MalT-like TPR region TPR_16 PF13432.6 OQR99921.1 - 0.03 15.0 8.9 3.7 8.3 0.0 3.9 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_4 PF07721.14 OQR99921.1 - 0.037 14.6 0.3 0.15 12.8 0.3 2.1 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_9 PF13371.6 OQR99921.1 - 0.079 13.1 2.3 0.35 11.1 0.7 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat SPO22 PF08631.10 OQR99921.1 - 0.087 12.3 0.4 0.19 11.2 0.4 1.6 1 0 0 1 1 1 0 Meiosis protein SPO22/ZIP4 like TPR_6 PF13174.6 OQR99921.1 - 0.12 13.1 6.1 16 6.4 0.6 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat MIT PF04212.18 OQR99921.1 - 0.2 11.7 5.0 0.42 10.7 0.2 2.9 3 0 0 3 3 3 0 MIT (microtubule interacting and transport) domain TPR_11 PF13414.6 OQR99921.1 - 1.4 8.6 5.5 0.96 9.2 0.1 3.4 3 1 1 4 4 4 0 TPR repeat Na_Ca_ex PF01699.24 OQR99922.1 - 3.4e-32 111.5 33.1 2.5e-16 60.0 14.1 2.2 2 0 0 2 2 2 2 Sodium/calcium exchanger protein S1-P1_nuclease PF02265.16 OQR99923.1 - 3.4e-34 118.8 0.2 4.2e-34 118.5 0.2 1.1 1 0 0 1 1 1 1 S1/P1 Nuclease SNF2_N PF00176.23 OQR99924.1 - 3.9e-48 164.0 0.0 6.8e-48 163.2 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 OQR99924.1 - 7.9e-18 64.8 0.0 2.6e-17 63.2 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 OQR99924.1 - 0.037 14.0 0.0 0.24 11.4 0.0 2.3 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit zinc_ribbon_4 PF13717.6 OQR99924.1 - 0.18 11.7 1.2 0.41 10.6 1.2 1.6 1 0 0 1 1 1 0 zinc-ribbon domain DTHCT PF08070.11 OQR99924.1 - 0.2 12.4 2.6 0.56 11.0 2.6 1.7 1 0 0 1 1 1 0 DTHCT (NUC029) region SPT6_acidic PF14632.6 OQR99924.1 - 6.9 7.3 19.7 19 5.9 19.7 1.7 1 0 0 1 1 1 0 Acidic N-terminal SPT6 FRQ PF09421.10 OQR99924.1 - 7.2 4.5 7.7 11 3.8 7.7 1.2 1 0 0 1 1 1 0 Frequency clock protein ACOX PF01756.19 OQR99925.1 - 2.9e-33 115.0 0.1 7.2e-33 113.7 0.1 1.7 1 0 0 1 1 1 1 Acyl-CoA oxidase Acyl-CoA_ox_N PF14749.6 OQR99925.1 - 5.8e-13 49.5 0.1 4.6e-12 46.6 0.1 2.1 2 0 0 2 2 2 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_M PF02770.19 OQR99925.1 - 1.1e-06 28.7 0.0 4.9e-06 26.7 0.0 2.1 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.24 OQR99925.1 - 0.13 12.5 0.0 0.2 11.8 0.0 1.3 1 0 0 1 1 1 0 Acyl-CoA dehydrogenase, C-terminal domain ubiquitin PF00240.23 OQR99926.1 - 3.1e-10 39.6 0.0 6.4e-10 38.6 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 OQR99926.1 - 0.034 14.0 0.0 0.065 13.1 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like ACC_central PF08326.12 OQR99927.1 - 3.4e-166 554.5 0.7 4.2e-166 554.3 0.7 1.1 1 0 0 1 1 1 1 Acetyl-CoA carboxylase, central region Carboxyl_trans PF01039.22 OQR99927.1 - 1e-155 519.2 0.0 1.5e-155 518.6 0.0 1.2 1 0 0 1 1 1 1 Carboxyl transferase domain CPSase_L_D2 PF02786.17 OQR99927.1 - 3.9e-47 160.5 0.0 7.1e-47 159.6 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 OQR99927.1 - 3.1e-25 88.8 0.0 7.9e-25 87.6 0.0 1.8 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 OQR99927.1 - 1.1e-23 83.4 0.0 5.6e-23 81.1 0.0 2.3 3 0 0 3 3 3 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.22 OQR99927.1 - 5.9e-11 42.0 0.0 1.6e-10 40.7 0.0 1.7 1 0 0 1 1 1 1 Biotin-requiring enzyme ATPgrasp_ST PF14397.6 OQR99927.1 - 0.012 14.9 0.0 0.024 13.9 0.0 1.4 1 0 0 1 1 1 0 Sugar-transfer associated ATP-grasp Dala_Dala_lig_C PF07478.13 OQR99927.1 - 0.17 11.4 0.1 0.55 9.7 0.0 1.9 2 0 0 2 2 2 0 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 OQR99927.1 - 0.18 11.4 0.0 0.41 10.2 0.0 1.5 1 0 0 1 1 1 0 ATP-grasp domain Sec1 PF00995.23 OQR99928.1 - 2.2e-116 390.4 2.9 3.1e-116 389.9 2.9 1.2 1 0 0 1 1 1 1 Sec1 family Cse1 PF08506.10 OQR99928.1 - 0.00012 21.0 0.6 0.00077 18.4 0.1 2.7 3 0 0 3 3 3 1 Cse1 CdiI_2 PF18593.1 OQR99928.1 - 0.15 12.7 1.7 1 10.0 0.3 3.1 2 0 0 2 2 2 0 CdiI immunity protein RTP1_C1 PF10363.9 OQR99928.1 - 1.4 9.1 3.6 35 4.6 0.2 3.8 3 1 1 4 4 4 0 Required for nuclear transport of RNA pol II C-terminus 1 Glyco_hydro_47 PF01532.20 OQR99949.1 - 4.5e-72 243.4 2.5 1.3e-71 241.9 2.5 1.6 1 1 0 1 1 1 1 Glycosyl hydrolase family 47 Heme_oxygenase PF01126.20 OQR99969.1 - 8.2e-65 218.4 0.2 1.2e-64 217.9 0.2 1.2 1 0 0 1 1 1 1 Heme oxygenase HTH_Tnp_Tc5 PF03221.16 OQR99970.1 - 6.2e-17 61.4 0.1 2e-16 59.8 0.0 1.9 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain CENP-B_N PF04218.13 OQR99970.1 - 1.3e-07 31.1 0.7 5.4e-06 25.9 0.2 3.1 4 0 0 4 4 4 1 CENP-B N-terminal DNA-binding domain MarR PF01047.22 OQR99970.1 - 0.00017 21.4 0.1 0.00069 19.5 0.0 2.1 3 0 0 3 3 2 1 MarR family HTH_Tnp_4 PF13613.6 OQR99970.1 - 0.0009 18.9 0.0 0.0019 17.9 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix of DDE superfamily endonuclease HTH_23 PF13384.6 OQR99970.1 - 0.0012 18.6 0.0 0.034 14.0 0.0 2.8 2 0 0 2 2 2 1 Homeodomain-like domain HTH_28 PF13518.6 OQR99970.1 - 0.0012 18.9 0.3 0.0066 16.5 0.0 2.4 2 1 1 3 3 2 1 Helix-turn-helix domain HTH_29 PF13551.6 OQR99970.1 - 0.0013 18.7 0.0 0.0062 16.5 0.0 2.1 2 0 0 2 2 2 1 Winged helix-turn helix LacI PF00356.21 OQR99970.1 - 0.0026 17.5 0.1 0.0056 16.4 0.1 1.5 1 0 0 1 1 1 1 Bacterial regulatory proteins, lacI family HTH_24 PF13412.6 OQR99970.1 - 0.003 17.1 0.8 0.01 15.4 0.0 2.2 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding HTH_38 PF13936.6 OQR99970.1 - 0.0033 17.2 0.1 0.01 15.6 0.1 2.0 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_36 PF13730.6 OQR99970.1 - 0.0037 17.2 0.0 0.011 15.7 0.0 1.8 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_Tnp_ISL3 PF13542.6 OQR99970.1 - 0.0042 16.5 0.1 0.022 14.2 0.0 2.1 2 0 0 2 2 2 1 Helix-turn-helix domain of transposase family ISL3 HTH_26 PF13443.6 OQR99970.1 - 0.0053 17.2 0.1 0.014 15.8 0.1 1.6 1 0 0 1 1 1 1 Cro/C1-type HTH DNA-binding domain HTH_50 PF18024.1 OQR99970.1 - 0.0094 15.5 0.1 0.024 14.2 0.1 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain Fe_dep_repress PF01325.19 OQR99970.1 - 0.011 15.9 0.1 0.041 14.1 0.0 1.9 2 0 0 2 2 2 0 Iron dependent repressor, N-terminal DNA binding domain HTH_IclR PF09339.10 OQR99970.1 - 0.012 15.4 0.1 0.041 13.7 0.1 1.9 1 0 0 1 1 1 0 IclR helix-turn-helix domain HTH_7 PF02796.15 OQR99970.1 - 0.03 14.4 0.2 0.2 11.8 0.0 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain of resolvase YdaS_antitoxin PF15943.5 OQR99970.1 - 0.034 14.0 0.0 0.13 12.1 0.0 2.1 2 0 0 2 2 2 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT HTH_10 PF04967.12 OQR99970.1 - 0.04 13.7 0.1 0.13 12.1 0.0 1.9 2 0 0 2 2 1 0 HTH DNA binding domain HTH_11 PF08279.12 OQR99970.1 - 0.058 13.3 0.6 0.22 11.5 0.0 2.3 2 0 0 2 2 2 0 HTH domain MarR_2 PF12802.7 OQR99970.1 - 0.067 13.1 0.0 0.18 11.7 0.0 1.7 1 0 0 1 1 1 0 MarR family HTH_Crp_2 PF13545.6 OQR99970.1 - 0.088 12.8 0.0 0.24 11.4 0.0 1.7 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain Sigma70_r4 PF04545.16 OQR99970.1 - 0.089 12.3 0.0 0.32 10.5 0.0 1.9 1 0 0 1 1 1 0 Sigma-70, region 4 PKD_channel PF08016.12 OQR99972.1 - 2.9e-20 72.4 15.9 9e-14 51.0 8.4 3.1 3 0 0 3 3 3 3 Polycystin cation channel Ion_trans PF00520.31 OQR99972.1 - 6e-11 42.0 15.9 1.4e-10 40.8 15.9 1.7 1 1 0 1 1 1 1 Ion transport protein Fe_dep_repress PF01325.19 OQR99972.1 - 0.074 13.3 0.2 12 6.2 0.1 2.4 2 0 0 2 2 2 0 Iron dependent repressor, N-terminal DNA binding domain PCMT PF01135.19 OQR99973.1 - 2.3e-35 122.3 0.0 2.9e-35 122.0 0.0 1.0 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.6 OQR99973.1 - 1.3e-09 38.0 0.1 2.6e-09 37.0 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 OQR99973.1 - 2.3e-07 31.4 0.0 4.7e-07 30.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 OQR99973.1 - 4.2e-06 26.8 0.0 6.1e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain AviRa PF11599.8 OQR99973.1 - 2.8e-05 23.7 0.0 4.5e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 RRNA methyltransferase AviRa Methyltransf_23 PF13489.6 OQR99973.1 - 3.7e-05 23.6 0.0 5e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OQR99973.1 - 5.5e-05 23.7 0.0 0.00012 22.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 OQR99973.1 - 0.00032 20.3 0.0 0.00056 19.5 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.13 OQR99973.1 - 0.00038 20.0 0.1 0.00056 19.4 0.0 1.3 1 1 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_12 PF08242.12 OQR99973.1 - 0.0021 18.7 0.0 0.004 17.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 OQR99973.1 - 0.0085 15.4 0.0 0.01 15.2 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_9 PF08003.11 OQR99973.1 - 0.01 14.8 0.0 0.014 14.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) GCD14 PF08704.10 OQR99973.1 - 0.03 14.0 0.0 0.036 13.7 0.0 1.2 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit Methyltransf_18 PF12847.7 OQR99973.1 - 0.031 14.2 0.0 0.055 13.4 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain CMAS PF02353.20 OQR99973.1 - 0.036 13.4 0.0 0.045 13.0 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase NodS PF05401.11 OQR99973.1 - 0.065 12.8 0.0 0.13 11.9 0.0 1.5 2 0 0 2 2 2 0 Nodulation protein S (NodS) Methyltransf_24 PF13578.6 OQR99973.1 - 0.072 14.1 0.0 0.17 12.9 0.0 1.6 2 0 0 2 2 2 0 Methyltransferase domain Ank_4 PF13637.6 OQR99974.1 - 1.2e-11 44.9 0.2 3.9e-09 36.9 0.1 3.2 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQR99974.1 - 1.2e-09 37.5 0.0 0.015 15.8 0.0 4.0 4 0 0 4 4 4 2 Ankyrin repeat Ank_2 PF12796.7 OQR99974.1 - 2e-09 37.9 0.1 1.1e-07 32.3 0.0 2.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OQR99974.1 - 1e-08 35.3 0.0 0.00076 19.7 0.0 2.4 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 OQR99974.1 - 0.00022 21.5 0.0 1.7 9.3 0.0 2.9 2 1 0 2 2 2 2 Ankyrin repeat FYVE PF01363.21 OQR99975.1 - 1.8e-17 63.2 32.5 5.2e-16 58.6 11.5 2.6 2 0 0 2 2 2 2 FYVE zinc finger C1_2 PF03107.16 OQR99975.1 - 0.012 15.9 9.9 0.012 15.9 9.9 3.4 2 1 1 3 3 3 0 C1 domain Mannosyl_trans2 PF04188.13 OQR99976.1 - 1.2e-52 179.7 42.0 1.7e-50 172.7 42.0 3.2 1 1 0 1 1 1 1 Mannosyltransferase (PIG-V) Peptidase_S32 PF05579.13 OQR99976.1 - 0.098 11.8 0.2 0.16 11.1 0.2 1.3 1 0 0 1 1 1 0 Equine arteritis virus serine endopeptidase S32 DUF2534 PF10749.9 OQR99976.1 - 0.12 12.5 3.8 1.4 9.1 0.9 3.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2534) K1 PF02960.14 OQR99976.1 - 0.26 11.4 0.1 0.26 11.4 0.1 2.3 3 0 0 3 3 3 0 K1 glycoprotein COMM_domain PF07258.14 OQR99978.1 - 4e-11 42.9 0.0 7.1e-11 42.1 0.0 1.4 1 0 0 1 1 1 1 COMM domain Dus PF01207.17 OQR99979.1 - 3.6e-74 249.7 0.1 3e-73 246.6 0.0 1.8 1 1 0 2 2 2 1 Dihydrouridine synthase (Dus) His_biosynth PF00977.21 OQR99979.1 - 0.0006 19.4 0.0 0.0012 18.3 0.0 1.5 1 0 0 1 1 1 1 Histidine biosynthesis protein G3P_antiterm PF04309.12 OQR99979.1 - 0.004 16.6 0.0 0.013 14.9 0.0 1.9 2 0 0 2 2 2 1 Glycerol-3-phosphate responsive antiterminator NMO PF03060.15 OQR99979.1 - 0.021 14.2 0.0 0.07 12.5 0.0 1.8 2 0 0 2 2 2 0 Nitronate monooxygenase IMPDH PF00478.25 OQR99979.1 - 0.028 13.4 0.1 0.044 12.8 0.1 1.2 1 0 0 1 1 1 0 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 OQR99979.1 - 0.053 12.5 0.0 0.079 12.0 0.0 1.2 1 0 0 1 1 1 0 FMN-dependent dehydrogenase SOR_SNZ PF01680.17 OQR99979.1 - 0.059 13.1 0.0 0.2 11.4 0.0 1.8 2 0 0 2 2 2 0 SOR/SNZ family ThiG PF05690.14 OQR99979.1 - 0.15 11.3 0.1 0.27 10.5 0.1 1.3 1 0 0 1 1 1 0 Thiazole biosynthesis protein ThiG UPF0061 PF02696.14 OQS00001.1 - 9.2e-105 351.1 0.0 1.7e-104 350.2 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized ACR, YdiU/UPF0061 family tRNA_U5-meth_tr PF05958.11 OQS00001.1 - 3e-12 46.2 0.2 7.5e-11 41.6 0.2 2.2 1 1 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase Met_10 PF02475.16 OQS00001.1 - 5.5e-06 26.3 0.0 1e-05 25.4 0.0 1.4 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_25 PF13649.6 OQS00001.1 - 1.4e-05 25.7 0.0 5.7e-05 23.8 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OQS00001.1 - 1.9e-05 24.5 0.0 5.8e-05 22.9 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_15 PF09445.10 OQS00001.1 - 5.1e-05 22.9 0.2 0.00013 21.6 0.0 1.8 2 0 0 2 2 2 1 RNA cap guanine-N2 methyltransferase MTS PF05175.14 OQS00001.1 - 0.00022 20.8 0.0 0.00069 19.2 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase small domain Cons_hypoth95 PF03602.15 OQS00001.1 - 0.00061 19.5 0.0 0.023 14.4 0.0 2.4 2 0 0 2 2 2 1 Conserved hypothetical protein 95 PrmA PF06325.13 OQS00001.1 - 0.0027 17.1 0.8 0.0049 16.3 0.1 1.7 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_11 PF08241.12 OQS00001.1 - 0.12 13.1 0.0 0.4 11.4 0.0 2.0 1 0 0 1 1 1 0 Methyltransferase domain Guanylate_cyc PF00211.20 OQS00002.1 - 5.2e-92 306.5 2.1 6.8e-48 162.7 0.1 2.6 2 1 0 2 2 2 2 Adenylate and Guanylate cyclase catalytic domain PhoLip_ATPase_C PF16212.5 OQS00002.1 - 1e-65 222.0 23.4 1e-65 222.0 23.4 4.2 4 0 0 4 4 4 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 OQS00002.1 - 5.3e-26 90.1 2.5 5.3e-26 90.1 2.5 2.5 2 0 0 2 2 2 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 OQS00002.1 - 3.1e-14 53.8 0.0 1.4e-09 38.6 0.0 3.3 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 OQS00002.1 - 5.3e-08 32.9 0.0 3.3e-07 30.3 0.0 2.2 2 0 0 2 2 2 1 Cation transport ATPase (P-type) E1-E2_ATPase PF00122.20 OQS00002.1 - 1.5e-06 27.9 0.0 1.5e-06 27.9 0.0 2.2 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase_3 PF08282.12 OQS00002.1 - 0.023 14.5 0.1 0.11 12.2 0.0 2.1 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase Pkinase PF00069.25 OQS00003.1 - 1e-30 107.0 0.2 1.2e-26 93.7 0.1 2.5 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OQS00003.1 - 1.1e-28 100.2 0.2 4.2e-25 88.5 0.0 2.6 1 1 1 2 2 2 2 Protein tyrosine kinase Ank_3 PF13606.6 OQS00003.1 - 0.1 13.2 0.0 0.41 11.4 0.0 2.1 1 0 0 1 1 1 0 Ankyrin repeat Lactonase PF10282.9 OQS00004.1 - 2.6e-72 244.0 0.6 3e-72 243.8 0.6 1.0 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller SGL PF08450.12 OQS00004.1 - 1.6e-05 24.6 0.1 0.033 13.8 0.0 3.1 1 1 1 3 3 3 2 SMP-30/Gluconolactonase/LRE-like region Cytochrom_D1 PF02239.16 OQS00004.1 - 0.00056 18.6 0.0 0.17 10.4 0.0 2.3 2 1 0 2 2 2 2 Cytochrome D1 heme domain NHL PF01436.21 OQS00004.1 - 0.016 15.2 1.4 0.89 9.7 0.0 3.1 3 0 0 3 3 3 0 NHL repeat Arylesterase PF01731.20 OQS00004.1 - 0.034 14.3 0.1 23 5.3 0.0 4.2 4 0 0 4 4 4 0 Arylesterase AAA_2 PF07724.14 OQS00005.1 - 8.1e-50 169.3 0.0 1.2e-48 165.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_lid_9 PF17871.1 OQS00005.1 - 1.9e-34 117.7 1.2 1.9e-34 117.7 1.2 3.9 3 1 1 4 4 4 1 AAA lid domain AAA PF00004.29 OQS00005.1 - 8.1e-25 87.8 0.0 6.4e-12 46.0 0.0 3.0 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.9 OQS00005.1 - 3.7e-21 75.0 0.1 2.3e-20 72.4 0.1 2.5 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.14 OQS00005.1 - 6.6e-18 65.0 0.2 3.8e-11 43.1 0.0 4.0 3 0 0 3 3 3 2 AAA domain (dynein-related subfamily) Clp_N PF02861.20 OQS00005.1 - 2.3e-14 53.2 0.1 1.1e-05 25.4 0.0 2.8 2 0 0 2 2 2 2 Clp amino terminal domain, pathogenicity island component PPR_2 PF13041.6 OQS00005.1 - 3.1e-13 49.7 1.8 0.00011 22.3 0.0 5.5 3 2 2 5 5 5 2 PPR repeat family PPR PF01535.20 OQS00005.1 - 2.2e-10 40.1 0.7 0.039 14.2 0.0 6.0 6 0 0 6 6 5 2 PPR repeat AAA_16 PF13191.6 OQS00005.1 - 1.3e-09 38.7 12.8 3.8e-05 24.1 0.0 5.4 4 2 1 5 5 4 2 AAA ATPase domain Sigma54_activat PF00158.26 OQS00005.1 - 2.6e-09 37.0 0.0 2.7e-07 30.5 0.0 2.6 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_22 PF13401.6 OQS00005.1 - 3.9e-09 36.9 0.4 0.0072 16.6 0.0 5.0 2 2 1 3 3 3 2 AAA domain IstB_IS21 PF01695.17 OQS00005.1 - 1.7e-07 31.1 0.4 0.013 15.2 0.0 3.3 4 0 0 4 4 2 2 IstB-like ATP binding protein Smr PF01713.21 OQS00005.1 - 1.2e-06 28.8 0.0 7.7e-06 26.2 0.0 2.5 2 0 0 2 2 1 1 Smr domain AAA_25 PF13481.6 OQS00005.1 - 5.9e-06 26.0 2.2 0.019 14.5 0.0 4.5 4 0 0 4 4 4 1 AAA domain Mg_chelatase PF01078.21 OQS00005.1 - 7.2e-06 25.5 0.0 1.3 8.3 0.0 3.5 3 0 0 3 3 3 2 Magnesium chelatase, subunit ChlI AAA_18 PF13238.6 OQS00005.1 - 1.6e-05 25.5 0.1 0.2 12.2 0.0 3.9 3 0 0 3 3 3 1 AAA domain AAA_7 PF12775.7 OQS00005.1 - 2e-05 24.2 0.0 0.062 12.8 0.0 3.0 2 0 0 2 2 2 2 P-loop containing dynein motor region ATPase_2 PF01637.18 OQS00005.1 - 2.9e-05 24.1 0.0 6.6 6.6 0.0 4.2 3 0 0 3 3 3 0 ATPase domain predominantly from Archaea AAA_3 PF07726.11 OQS00005.1 - 3.2e-05 23.8 0.0 0.0097 15.8 0.0 3.4 3 1 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 OQS00005.1 - 7.8e-05 22.7 0.0 0.21 11.6 0.0 2.9 2 0 0 2 2 2 2 AAA domain NACHT PF05729.12 OQS00005.1 - 0.00014 21.8 0.0 0.87 9.5 0.0 3.8 3 0 0 3 3 3 1 NACHT domain RuvB_N PF05496.12 OQS00005.1 - 0.00019 21.2 3.6 0.079 12.7 0.0 4.6 4 1 0 4 4 3 1 Holliday junction DNA helicase RuvB P-loop domain PPR_3 PF13812.6 OQS00005.1 - 0.00023 21.2 3.1 0.29 11.2 0.1 5.1 4 1 1 5 5 5 1 Pentatricopeptide repeat domain Roc PF08477.13 OQS00005.1 - 0.00068 19.8 0.0 1.7 8.9 0.0 2.8 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase RNA_helicase PF00910.22 OQS00005.1 - 0.00069 20.0 0.1 0.99 9.8 0.0 3.1 3 0 0 3 3 2 1 RNA helicase DNA_pol3_delta2 PF13177.6 OQS00005.1 - 0.00097 18.9 0.1 0.98 9.2 0.0 3.4 3 0 0 3 3 3 1 DNA polymerase III, delta subunit AAA_28 PF13521.6 OQS00005.1 - 0.0017 18.7 1.9 9.2 6.5 0.0 4.6 4 1 0 4 4 4 0 AAA domain TIP49 PF06068.13 OQS00005.1 - 0.0032 16.7 0.1 2.4 7.3 0.0 2.5 2 0 0 2 2 2 2 TIP49 P-loop domain DUF815 PF05673.13 OQS00005.1 - 0.0069 15.6 0.0 5.9 6.0 0.0 3.0 2 1 0 2 2 2 0 Protein of unknown function (DUF815) AAA_33 PF13671.6 OQS00005.1 - 0.0074 16.5 0.0 2.2 8.5 0.0 3.2 3 0 0 3 3 2 1 AAA domain RsgA_GTPase PF03193.16 OQS00005.1 - 0.0078 16.1 1.1 7.1 6.5 0.0 3.8 4 0 0 4 4 3 0 RsgA GTPase AAA_24 PF13479.6 OQS00005.1 - 0.011 15.4 0.0 3.6 7.2 0.0 3.0 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 OQS00005.1 - 0.012 15.6 0.0 9.6 6.2 0.0 2.6 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ABC_tran PF00005.27 OQS00005.1 - 0.013 16.0 3.4 1.8 9.1 0.0 4.4 4 1 0 4 4 3 0 ABC transporter ResIII PF04851.15 OQS00005.1 - 0.02 14.9 0.0 0.37 10.8 0.0 3.1 3 0 0 3 3 3 0 Type III restriction enzyme, res subunit AAA_29 PF13555.6 OQS00005.1 - 0.053 13.3 0.0 13 5.6 0.0 2.9 2 0 0 2 2 2 0 P-loop containing region of AAA domain DUF87 PF01935.17 OQS00005.1 - 0.13 12.3 7.5 5.4 7.0 0.0 5.2 6 0 0 6 6 6 0 Helicase HerA, central domain AAA_19 PF13245.6 OQS00005.1 - 0.18 12.2 1.6 2.4 8.5 0.2 3.4 2 2 0 2 2 2 0 AAA domain AAA_23 PF13476.6 OQS00005.1 - 0.58 10.6 0.0 0.58 10.6 0.0 4.2 3 1 0 5 5 2 0 AAA domain DNA_topoisoIV PF00521.20 OQS00007.1 - 1.3e-112 376.9 0.0 2e-112 376.2 0.0 1.3 1 0 0 1 1 1 1 DNA gyrase/topoisomerase IV, subunit A TOPRIM_C PF16898.5 OQS00007.1 - 2.8e-40 137.5 0.7 7.8e-40 136.1 0.7 1.8 1 0 0 1 1 1 1 C-terminal associated domain of TOPRIM DNA_gyraseB PF00204.25 OQS00007.1 - 2.1e-19 69.7 0.7 3.7e-19 68.9 0.7 1.4 1 0 0 1 1 1 1 DNA gyrase B HATPase_c PF02518.26 OQS00007.1 - 8.5e-09 35.9 0.0 2.4e-08 34.5 0.0 1.9 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Toprim PF01751.22 OQS00007.1 - 1.9e-06 28.0 0.0 6.6e-06 26.3 0.0 1.9 1 0 0 1 1 1 1 Toprim domain PX PF00787.24 OQS00007.1 - 7.2e-05 22.7 0.3 0.00045 20.2 0.0 2.5 3 0 0 3 3 3 1 PX domain GerD PF17898.1 OQS00007.1 - 0.12 12.3 2.1 11 5.9 0.1 3.3 3 0 0 3 3 3 0 Spore germination GerD central core domain Globin PF00042.22 OQS00008.1 - 0.22 12.1 0.4 1 9.9 0.4 2.0 1 1 0 1 1 1 0 Globin Aa_trans PF01490.18 OQS00009.1 - 1e-59 202.3 33.3 1.3e-59 201.9 33.3 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein B277 PF17623.2 OQS00009.1 - 0.0071 15.5 0.1 0.012 14.7 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function Dabb PF07876.12 OQS00010.1 - 1.1e-21 77.3 0.1 1.2e-21 77.1 0.1 1.0 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain FYVE PF01363.21 OQS00011.1 - 4.9e-06 26.6 10.7 1.7e-05 24.9 10.7 1.9 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.16 OQS00011.1 - 1.4 9.1 10.3 3.8 7.7 10.3 1.7 1 0 0 1 1 1 0 FYVE-type zinc finger DZR PF12773.7 OQS00011.1 - 3.6 7.7 18.5 10 6.2 12.5 3.0 2 1 1 3 3 3 0 Double zinc ribbon zf-C3HC4 PF00097.25 OQS00011.1 - 8.1 6.4 11.6 15 5.6 10.6 2.1 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Ribosomal_L20 PF00453.18 OQS00013.1 - 4.1e-41 139.4 1.8 4.6e-41 139.2 1.8 1.0 1 0 0 1 1 1 1 Ribosomal protein L20 Peptidase_C15 PF01470.17 OQS00014.1 - 8.9e-55 186.0 0.0 3.5e-24 86.1 0.0 3.0 2 1 1 3 3 3 3 Pyroglutamyl peptidase PgaPase_1 PF06162.12 OQS00014.1 - 0.0029 17.4 0.0 3.6 7.3 0.0 2.8 3 0 0 3 3 3 2 Putative pyroglutamyl peptidase PgaPase_1 RNA_lig_T4_1 PF09511.10 OQS00014.1 - 0.045 13.6 0.0 7.4 6.4 0.0 2.4 2 0 0 2 2 2 0 RNA ligase Lipase_GDSL_2 PF13472.6 OQS00014.1 - 0.059 13.8 0.0 0.34 11.3 0.0 2.2 3 0 0 3 3 3 0 GDSL-like Lipase/Acylhydrolase family Bowman-Birk_leg PF00228.20 OQS00014.1 - 0.073 13.5 3.3 4.3 7.8 0.1 3.2 3 0 0 3 3 3 0 Bowman-Birk serine protease inhibitor family LINES_N PF14694.6 OQS00014.1 - 0.084 12.3 0.1 0.13 11.7 0.1 1.2 1 0 0 1 1 1 0 Lines N-terminus SPA PF08616.10 OQS00015.1 - 3.9e-06 26.8 0.0 1.5e-05 24.9 0.0 1.9 2 0 0 2 2 2 1 Stabilization of polarity axis Avl9 PF09794.9 OQS00015.1 - 3.5e-05 22.7 0.0 7.1e-05 21.7 0.0 1.5 1 0 0 1 1 1 1 Transport protein Avl9 Cpn60_TCP1 PF00118.24 OQS00016.1 - 5.2e-153 510.2 1.4 1.1e-152 509.2 0.1 1.8 2 0 0 2 2 2 1 TCP-1/cpn60 chaperonin family ATP-gua_Ptrans PF00217.19 OQS00016.1 - 2.1e-73 246.3 0.0 3.2e-73 245.7 0.0 1.3 1 0 0 1 1 1 1 ATP:guanido phosphotransferase, C-terminal catalytic domain ATP-gua_PtransN PF02807.15 OQS00016.1 - 1.3e-26 92.7 0.0 3.3e-26 91.5 0.0 1.7 1 0 0 1 1 1 1 ATP:guanido phosphotransferase, N-terminal domain DUF2121 PF09894.9 OQS00016.1 - 0.05 13.1 0.0 0.11 12.0 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2121) Acetyltransf_2 PF00797.17 OQS00017.1 - 3.9e-100 334.6 0.0 7.1e-49 166.8 0.0 2.5 2 1 0 2 2 2 2 N-acetyltransferase Transglut_core PF01841.19 OQS00017.1 - 0.0012 19.3 0.0 2.2 8.8 0.0 2.5 2 0 0 2 2 2 2 Transglutaminase-like superfamily FAM47 PF14642.6 OQS00017.1 - 0.071 12.6 0.1 1.6 8.2 0.0 2.1 2 0 0 2 2 2 0 FAM47 family ABC1 PF03109.16 OQS00018.1 - 4.6e-26 91.3 0.0 1e-25 90.2 0.0 1.6 1 0 0 1 1 1 1 ABC1 family APH PF01636.23 OQS00018.1 - 0.00055 19.9 0.3 0.0099 15.8 0.3 2.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family Pkinase PF00069.25 OQS00018.1 - 0.01 15.2 0.3 2.2 7.6 0.0 3.1 3 0 0 3 3 3 0 Protein kinase domain DUF1500 PF07389.12 OQS00018.1 - 0.017 15.2 0.1 0.11 12.6 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1500) GP24_25 PF17388.2 OQS00018.1 - 0.13 12.3 1.5 1.3 9.0 0.1 2.5 2 0 0 2 2 2 0 Tail assembly gene products 24 & 25 Tau95 PF09734.9 OQS00019.1 - 1.6e-30 106.8 2.7 1.6e-30 106.7 0.6 2.1 2 0 0 2 2 2 1 RNA polymerase III transcription factor (TF)IIIC subunit HTH domain Tau95_N PF17682.1 OQS00019.1 - 2e-14 53.9 1.2 3e-12 46.9 0.1 3.2 2 1 0 2 2 2 1 Tau95 Triple barrel domain CCSMST1 PF15013.6 OQS00019.1 - 0.13 12.5 0.0 0.38 10.9 0.0 1.8 1 0 0 1 1 1 0 CCSMST1 family Astro_capsid_p PF12226.8 OQS00019.1 - 5.6 6.0 8.8 11 5.0 8.8 1.4 1 0 0 1 1 1 0 Turkey astrovirus capsid protein PPP4R2 PF09184.11 OQS00019.1 - 8.6 5.8 13.9 1.8 8.1 7.1 2.2 2 0 0 2 2 2 0 PPP4R2 Methyltransf_16 PF10294.9 OQS00020.1 - 1.2e-10 41.3 0.0 1.7e-10 40.9 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase AOX PF01786.17 OQS00021.1 - 1.5e-92 309.1 0.1 1.8e-92 308.8 0.1 1.1 1 0 0 1 1 1 1 Alternative oxidase GST_N_3 PF13417.6 OQS00022.1 - 6.7e-11 42.4 0.0 1.7e-10 41.2 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 OQS00022.1 - 8.9e-11 42.0 0.0 1.1e-09 38.5 0.0 2.3 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_5 PF16865.5 OQS00022.1 - 1.1e-09 38.8 0.1 2.8e-09 37.5 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 OQS00022.1 - 1e-08 35.3 0.0 2.2e-08 34.3 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 OQS00022.1 - 0.00035 20.5 0.0 0.00062 19.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 OQS00022.1 - 0.00067 19.8 0.1 0.0012 19.0 0.1 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Glutaredoxin PF00462.24 OQS00022.1 - 0.17 12.1 0.0 0.42 10.9 0.0 1.7 1 0 0 1 1 1 0 Glutaredoxin EF-hand_7 PF13499.6 OQS00023.1 - 2.2e-30 104.9 5.9 4.2e-09 36.7 1.2 5.0 4 1 2 6 6 6 5 EF-hand domain pair EF-hand_6 PF13405.6 OQS00023.1 - 6.7e-27 91.1 7.2 8.6e-06 25.3 0.2 7.8 8 0 0 8 8 8 5 EF-hand domain EF-hand_1 PF00036.32 OQS00023.1 - 2.3e-23 79.9 12.7 1.1e-05 24.6 1.3 7.7 7 0 0 7 7 7 6 EF hand EF-hand_8 PF13833.6 OQS00023.1 - 7.1e-16 57.8 12.3 3.3e-07 30.0 1.4 7.2 6 1 1 7 7 7 4 EF-hand domain pair EF-hand_5 PF13202.6 OQS00023.1 - 1.2e-10 40.4 10.8 0.0024 17.3 0.0 4.5 5 0 0 5 5 5 3 EF hand EF-hand_10 PF14788.6 OQS00023.1 - 2.5e-07 30.4 0.2 0.025 14.5 0.1 3.8 4 0 0 4 4 4 2 EF hand DUF4483 PF14825.6 OQS00023.1 - 2.4e-06 27.4 0.0 2.4e-06 27.4 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4483) SPARC_Ca_bdg PF10591.9 OQS00023.1 - 0.022 15.1 0.9 3.5 8.0 0.9 3.8 3 1 0 3 3 3 0 Secreted protein acidic and rich in cysteine Ca binding region AMP-binding PF00501.28 OQS00024.1 - 1.4e-21 76.6 0.6 1.9e-21 76.2 0.6 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 OQS00024.1 - 6e-06 27.2 0.1 1e-05 26.4 0.1 1.4 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain NAD_binding_6 PF08030.12 OQS00025.1 - 0.067 13.3 0.3 0.16 12.1 0.3 1.6 1 0 0 1 1 1 0 Ferric reductase NAD binding domain IQ PF00612.27 OQS00026.1 - 0.0021 17.7 1.2 0.0035 17.0 1.2 1.4 1 0 0 1 1 1 1 IQ calmodulin-binding motif Hom_end PF05204.14 OQS00027.1 - 0.0069 16.5 1.9 0.02 15.1 1.9 1.7 1 0 0 1 1 1 1 Homing endonuclease Val_tRNA-synt_C PF10458.9 OQS00027.1 - 0.029 14.6 1.3 0.029 14.6 1.3 4.5 4 1 0 4 4 4 0 Valyl tRNA synthetase tRNA binding arm Arm-DNA-bind_2 PF12167.8 OQS00027.1 - 0.14 12.1 0.1 0.44 10.5 0.1 1.9 1 0 0 1 1 1 0 Arm DNA-binding domain DUF5623 PF18536.1 OQS00027.1 - 0.65 10.3 4.8 0.32 11.3 1.0 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF5623) CENP-H PF05837.12 OQS00027.1 - 5.8 7.4 36.1 4.4 7.8 8.2 4.8 2 2 3 5 5 5 0 Centromere protein H (CENP-H) HSF_DNA-bind PF00447.17 OQS00028.1 - 2.7e-29 101.6 3.3 6.3e-29 100.5 2.5 1.9 2 0 0 2 2 2 1 HSF-type DNA-binding Bap31_Bap29_C PF18035.1 OQS00028.1 - 2.4e-06 27.5 0.3 3.8e-06 26.8 0.3 1.4 1 0 0 1 1 1 1 Bap31/Bap29 cytoplasmic coiled-coil domain UBA2_C PF16195.5 OQS00028.1 - 0.012 16.3 0.4 0.023 15.4 0.4 1.4 1 0 0 1 1 1 0 SUMO-activating enzyme subunit 2 C-terminus DUF2718 PF10918.8 OQS00028.1 - 0.015 15.8 0.0 0.027 15.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2718) DivIC PF04977.15 OQS00028.1 - 0.021 14.6 0.9 0.036 13.8 0.9 1.3 1 0 0 1 1 1 0 Septum formation initiator TMF_DNA_bd PF12329.8 OQS00028.1 - 0.022 14.7 0.0 0.036 14.1 0.0 1.2 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding Cast PF10174.9 OQS00028.1 - 0.053 11.8 0.4 0.067 11.4 0.4 1.1 1 0 0 1 1 1 0 RIM-binding protein of the cytomatrix active zone NPV_P10 PF05531.12 OQS00028.1 - 0.061 13.8 1.5 0.13 12.7 1.5 1.6 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein PspA_IM30 PF04012.12 OQS00028.1 - 0.15 11.6 0.4 0.23 11.0 0.4 1.2 1 0 0 1 1 1 0 PspA/IM30 family TolA_bind_tri PF16331.5 OQS00028.1 - 0.21 11.7 2.0 0.39 10.8 2.0 1.4 1 0 0 1 1 1 0 TolA binding protein trimerisation Aldo_ket_red PF00248.21 OQS00029.1 - 4.7e-25 88.4 0.0 7e-25 87.8 0.0 1.2 1 0 0 1 1 1 1 Aldo/keto reductase family UDG PF03167.19 OQS00029.1 - 0.12 12.3 0.0 0.36 10.8 0.0 1.7 2 0 0 2 2 2 0 Uracil DNA glycosylase superfamily Hydrolase_4 PF12146.8 OQS00030.1 - 1.4e-58 198.0 2.2 2.7e-57 193.8 2.2 2.0 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 OQS00030.1 - 3.1e-09 37.8 0.1 4.5e-09 37.2 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 OQS00030.1 - 8.2e-07 28.9 1.3 5.8e-06 26.1 1.1 2.2 2 1 0 2 2 2 1 alpha/beta hydrolase fold Chlorophyllase2 PF12740.7 OQS00030.1 - 0.00048 19.1 0.1 0.001 18.1 0.1 1.5 1 1 0 1 1 1 1 Chlorophyllase enzyme Peptidase_S9 PF00326.21 OQS00030.1 - 0.00086 18.8 0.4 0.005 16.3 0.0 2.3 3 0 0 3 3 3 1 Prolyl oligopeptidase family XRCC1_N PF01834.16 OQS00031.1 - 0.0067 16.4 0.0 0.012 15.6 0.0 1.4 1 1 0 1 1 1 1 XRCC1 N terminal domain cNMP_binding PF00027.29 OQS00032.1 - 5.8e-15 55.1 0.2 1.5e-08 34.5 0.0 3.5 2 2 0 2 2 2 2 Cyclic nucleotide-binding domain Sugar_tr PF00083.24 OQS00033.1 - 4.7e-42 144.4 19.6 6e-42 144.0 19.6 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OQS00033.1 - 1.2e-36 126.3 37.5 1.9e-36 125.7 37.5 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.6 OQS00033.1 - 6.6e-11 41.4 29.9 2.2e-07 29.8 1.0 4.0 3 1 0 4 4 4 4 MFS/sugar transport protein MFS_4 PF06779.14 OQS00033.1 - 0.0021 17.4 4.3 0.0021 17.4 4.3 2.2 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB CHAT PF12770.7 OQS00034.1 - 8.3e-13 48.4 0.5 1.1e-12 48.0 0.5 1.1 1 0 0 1 1 1 1 CHAT domain Peptidase_C14 PF00656.22 OQS00034.1 - 0.0022 18.0 0.0 0.003 17.5 0.0 1.3 1 0 0 1 1 1 1 Caspase domain XAF1_C PF18608.1 OQS00034.1 - 0.12 12.0 0.6 0.23 11.0 0.6 1.5 1 0 0 1 1 1 0 XIAP-associated factor 1 C-terminal domain AMP-binding PF00501.28 OQS00035.1 - 7.6e-136 453.0 0.2 3e-89 299.6 0.0 3.1 3 0 0 3 3 3 3 AMP-binding enzyme AMP-binding_C PF13193.6 OQS00035.1 - 0.00027 21.9 0.0 0.00084 20.3 0.0 1.9 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Glyco_H_20C_C PF18088.1 OQS00036.1 - 0.11 12.4 0.2 0.19 11.5 0.2 1.4 1 0 0 1 1 1 0 Glycoside Hydrolase 20C C-terminal domain DUF1604 PF07713.13 OQS00037.1 - 3.1e-27 94.2 0.6 3.1e-27 94.2 0.6 3.7 4 0 0 4 4 4 1 Protein of unknown function (DUF1604) G-patch PF01585.23 OQS00037.1 - 1e-06 28.5 0.4 2.3e-06 27.4 0.4 1.6 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 OQS00037.1 - 0.039 14.1 0.0 0.039 14.1 0.0 3.0 3 1 0 3 3 3 0 G-patch domain SRP-alpha_N PF04086.13 OQS00037.1 - 0.059 13.3 23.4 0.13 12.2 23.4 1.6 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal SDA1 PF05285.12 OQS00037.1 - 0.086 12.3 23.9 0.13 11.6 23.9 1.3 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.14 OQS00037.1 - 9.5 4.4 21.6 15 3.7 21.6 1.3 1 0 0 1 1 1 0 CDC45-like protein TM231 PF10149.9 OQS00038.1 - 8.2e-59 199.4 7.0 9.1e-59 199.2 7.0 1.0 1 0 0 1 1 1 1 Transmembrane protein 231 RRM_1 PF00076.22 OQS00039.1 - 2.3e-34 117.0 0.0 8.7e-16 57.5 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 OQS00039.1 - 2.7e-07 30.6 0.0 0.0087 16.2 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif Nup35_RRM_2 PF14605.6 OQS00039.1 - 0.001 19.0 0.0 0.0095 15.9 0.0 2.1 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif DTHCT PF08070.11 OQS00039.1 - 0.0054 17.4 83.6 0.15 12.8 38.1 4.1 1 1 4 5 5 5 4 DTHCT (NUC029) region Ribosomal_60s PF00428.19 OQS00040.1 - 1.5e-16 60.7 5.3 1.9e-16 60.4 5.3 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein PI3_PI4_kinase PF00454.27 OQS00041.1 - 1.3e-50 172.6 0.0 1.9e-50 172.0 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.20 OQS00041.1 - 4.4e-23 81.6 0.2 1e-22 80.5 0.2 1.6 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) DUF4135 PF13575.6 OQS00041.1 - 0.035 13.4 0.0 0.074 12.4 0.0 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4135) Pro_isomerase PF00160.21 OQS00042.1 - 4.6e-74 248.0 0.4 3.8e-37 128.0 0.0 2.1 2 0 0 2 2 2 2 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD MTCP1 PF08991.10 OQS00042.1 - 0.01 16.1 0.0 1.4 9.2 0.0 2.3 2 0 0 2 2 2 2 Mature-T-Cell Proliferation I type UCH_1 PF13423.6 OQS00044.1 - 4.5e-36 125.1 0.9 1.3e-26 94.0 0.6 2.7 1 1 2 3 3 3 2 Ubiquitin carboxyl-terminal hydrolase UCH PF00443.29 OQS00044.1 - 0.0031 17.1 0.1 0.013 15.0 0.2 1.9 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase RcnB PF11776.8 OQS00044.1 - 0.017 15.1 0.9 0.073 13.1 0.0 2.5 2 0 0 2 2 2 0 Nickel/cobalt transporter regulator WD40 PF00400.32 OQS00044.1 - 0.033 15.1 0.3 1.5 9.8 0.0 3.5 4 0 0 4 4 4 0 WD domain, G-beta repeat DUF2807 PF10988.8 OQS00045.1 - 1.3e-16 60.9 17.0 6.4e-10 39.1 5.0 2.1 1 1 1 2 2 2 2 Putative auto-transporter adhesin, head GIN domain AMP-binding PF00501.28 OQS00047.1 - 4.7e-95 318.7 0.3 5.9e-95 318.3 0.3 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 OQS00047.1 - 1.2e-22 80.7 0.6 3.4e-22 79.2 0.2 2.0 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain ACAS_N PF16177.5 OQS00047.1 - 1.2e-18 66.8 0.7 2.6e-18 65.7 0.7 1.6 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus DBR1 PF05011.13 OQS00048.1 - 2.7e-23 82.9 0.0 4.1e-23 82.4 0.0 1.3 1 0 0 1 1 1 1 Lariat debranching enzyme, C-terminal domain Metallophos PF00149.28 OQS00048.1 - 4.4e-12 46.9 0.2 7.7e-12 46.1 0.2 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 OQS00048.1 - 0.00057 20.1 0.0 0.0059 16.8 0.0 2.2 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain zf-H2C2_2 PF13465.6 OQS00049.1 - 3.1e-14 52.7 38.0 8.3e-07 29.2 0.2 5.2 5 0 0 5 5 5 3 Zinc-finger double domain zf-C2H2 PF00096.26 OQS00049.1 - 8e-12 44.9 40.9 0.00011 22.5 0.2 4.6 5 0 0 5 5 5 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 OQS00049.1 - 9.5e-10 38.5 33.8 0.00078 20.1 0.3 4.6 4 0 0 4 4 4 4 C2H2-type zinc finger zf-C2H2_6 PF13912.6 OQS00049.1 - 0.0083 16.1 0.7 0.0083 16.1 0.7 4.9 4 1 0 4 4 4 1 C2H2-type zinc finger NB PF04159.13 OQS00049.1 - 0.37 10.9 0.2 0.37 10.9 0.2 1.9 1 1 0 2 2 2 0 NB glycoprotein FOXP-CC PF16159.5 OQS00049.1 - 0.47 11.1 15.0 0.89 10.2 0.2 3.8 1 1 3 4 4 4 0 FOXP coiled-coil domain CDC24_OB3 PF17244.2 OQS00049.1 - 1.6 8.4 11.7 0.1 12.3 3.6 2.3 1 1 1 2 2 2 0 Cell division control protein 24, OB domain 3 CCAP PF11105.8 OQS00049.1 - 5 7.1 6.7 21 5.1 6.4 2.1 1 1 0 1 1 1 0 Arthropod cardioacceleratory peptide 2a bZIP_1 PF00170.21 OQS00050.1 - 4.9e-06 26.5 17.5 4.9e-06 26.5 17.5 2.8 2 1 1 3 3 3 1 bZIP transcription factor bZIP_2 PF07716.15 OQS00050.1 - 8.6e-06 25.7 17.8 8.6e-06 25.7 17.8 3.4 3 0 0 3 3 3 2 Basic region leucine zipper DUF601 PF04642.12 OQS00050.1 - 0.00043 19.9 0.7 0.00086 18.9 0.7 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF601 SapB_1 PF05184.15 OQS00050.1 - 0.14 12.2 0.1 0.31 11.1 0.1 1.6 1 0 0 1 1 1 0 Saposin-like type B, region 1 START PF01852.19 OQS00051.1 - 9.9e-11 41.4 0.0 1.9e-10 40.5 0.0 1.4 1 1 0 1 1 1 1 START domain FYVE PF01363.21 OQS00051.1 - 0.2 11.8 6.6 0.51 10.5 6.6 1.6 1 0 0 1 1 1 0 FYVE zinc finger FYVE_2 PF02318.16 OQS00051.1 - 0.2 11.9 3.9 0.49 10.6 3.9 1.6 1 0 0 1 1 1 0 FYVE-type zinc finger Bromodomain PF00439.25 OQS00052.1 - 2.9e-22 78.5 1.3 4.1e-22 78.1 0.4 1.7 2 0 0 2 2 2 1 Bromodomain Acetyltransf_1 PF00583.25 OQS00052.1 - 9.6e-11 41.9 0.1 1.7e-10 41.1 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 OQS00052.1 - 1.3e-09 38.0 0.0 2.4e-09 37.2 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 OQS00052.1 - 1.4e-06 28.6 0.5 2.9e-06 27.6 0.5 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 OQS00052.1 - 0.00043 20.2 0.0 0.001 19.0 0.0 1.6 1 0 0 1 1 1 1 FR47-like protein Fucose_iso_N2 PF07882.12 OQS00052.1 - 0.016 14.8 0.1 0.035 13.7 0.1 1.5 1 0 0 1 1 1 0 L-fucose isomerase, second N-terminal domain DHHC PF01529.20 OQS00053.1 - 7.8e-19 68.1 7.9 7.8e-19 68.1 7.9 2.6 2 1 0 2 2 2 1 DHHC palmitoyltransferase DUF3611 PF12263.8 OQS00053.1 - 0.024 14.5 0.7 0.024 14.5 0.7 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3611) YtpI PF14007.6 OQS00053.1 - 0.036 14.2 0.9 0.036 14.2 0.9 2.5 2 2 0 2 2 2 0 YtpI-like protein DUF2852 PF11014.8 OQS00053.1 - 0.19 11.9 0.2 2 8.6 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2852) EI24 PF07264.11 OQS00053.1 - 2.3 8.4 12.9 5.5 7.2 12.9 1.5 1 1 0 1 1 1 0 Etoposide-induced protein 2.4 (EI24) KH_1 PF00013.29 OQS00054.1 - 2.5e-59 197.0 12.8 1.6e-19 69.5 0.5 4.2 4 0 0 4 4 4 4 KH domain KH_2 PF07650.17 OQS00054.1 - 1.6e-11 43.9 6.3 0.015 15.1 0.0 4.4 4 0 0 4 4 4 3 KH domain KH_4 PF13083.6 OQS00054.1 - 1.2e-10 41.2 8.0 0.005 16.7 0.2 4.5 4 1 0 4 4 4 3 KH domain KH_5 PF13184.6 OQS00054.1 - 5.5e-05 23.2 2.7 4.1 7.6 0.0 4.3 4 0 0 4 4 4 2 NusA-like KH domain SLS PF14611.6 OQS00054.1 - 0.017 14.9 0.0 1.3 8.8 0.0 2.5 2 0 0 2 2 2 0 Mitochondrial inner-membrane-bound regulator Gln-synt_C PF00120.24 OQS00055.1 - 7.6e-19 67.9 0.0 1.6e-17 63.5 0.0 2.3 1 1 0 1 1 1 1 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.19 OQS00055.1 - 3.3e-14 52.4 0.0 5.9e-14 51.6 0.0 1.4 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain UPF0242 PF06785.11 OQS00056.1 - 0.0099 16.0 1.1 0.0099 16.0 1.1 1.8 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0242) N-terminus EIF_2_alpha PF07541.12 OQS00056.1 - 0.02 15.0 0.0 0.04 14.0 0.0 1.5 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 2 alpha subunit LytTR PF04397.15 OQS00056.1 - 0.052 13.8 0.1 0.11 12.8 0.1 1.4 1 0 0 1 1 1 0 LytTr DNA-binding domain Epsilon_antitox PF08998.11 OQS00056.1 - 0.084 13.2 0.8 0.18 12.1 0.8 1.5 1 0 0 1 1 1 0 Bacterial epsilon antitoxin Cytochrom_B562 PF07361.11 OQS00056.1 - 0.16 12.6 1.5 9 7.0 0.2 2.3 2 0 0 2 2 2 0 Cytochrome b562 SlyX PF04102.12 OQS00056.1 - 4.8 7.9 7.9 2.6 8.7 0.7 3.4 4 0 0 4 4 4 0 SlyX Myb_DNA-bind_7 PF15963.5 OQS00057.1 - 1.2e-22 79.6 0.8 1.2e-22 79.6 0.8 2.8 2 1 1 3 3 3 1 Myb DNA-binding like Myb_DNA-binding PF00249.31 OQS00057.1 - 0.013 15.7 0.0 0.032 14.4 0.0 1.7 1 0 0 1 1 1 0 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OQS00057.1 - 0.066 13.5 0.0 0.16 12.3 0.0 1.6 1 0 0 1 1 1 0 Myb-like DNA-binding domain SURF2 PF05477.11 OQS00058.1 - 1e-32 113.7 11.6 1e-32 113.7 11.6 2.1 2 0 0 2 2 2 1 Surfeit locus protein 2 (SURF2) Peptidase_C12 PF01088.21 OQS00058.1 - 1.6e-28 99.9 0.4 1.6e-28 99.9 0.4 2.2 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase, family 1 DUF3767 PF12597.8 OQS00058.1 - 1e-14 54.1 0.2 1e-14 54.1 0.2 2.3 1 1 1 2 2 2 1 Protein of unknown function (DUF3767) CDC45 PF02724.14 OQS00058.1 - 0.0018 16.6 12.0 0.0018 16.6 12.0 1.6 2 0 0 2 2 2 1 CDC45-like protein DUF3568 PF12092.8 OQS00058.1 - 0.0081 16.2 0.7 0.054 13.6 0.0 2.5 2 1 1 3 3 3 1 Protein of unknown function (DUF3568) Sial-lect-inser PF09264.10 OQS00058.1 - 0.024 14.4 0.1 0.053 13.3 0.0 1.5 1 1 0 1 1 1 0 Vibrio cholerae sialidase, lectin insertion GramPos_pilinD1 PF16555.5 OQS00058.1 - 0.06 13.5 14.1 0.22 11.7 10.4 2.4 2 0 0 2 2 2 0 Gram-positive pilin subunit D1, N-terminal domain TM2 PF05154.16 OQS00058.1 - 0.086 13.2 0.4 0.17 12.3 0.4 1.4 1 0 0 1 1 1 0 TM2 domain Pex14_N PF04695.13 OQS00058.1 - 0.51 11.0 7.2 0.061 14.0 2.1 2.0 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Presenilin PF01080.17 OQS00058.1 - 0.78 8.4 6.7 0.11 11.2 2.1 1.8 2 0 0 2 2 2 0 Presenilin Hid1 PF12722.7 OQS00058.1 - 5.7 4.9 7.7 10 4.1 7.7 1.4 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein GST_C_2 PF13410.6 OQS00060.1 - 7.5e-08 32.3 0.0 1.5e-07 31.3 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 OQS00060.1 - 4.5e-06 27.0 0.0 1.9e-05 25.0 0.0 2.1 2 1 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 OQS00060.1 - 0.0015 18.8 0.0 0.0037 17.5 0.0 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 OQS00060.1 - 0.022 14.9 0.0 0.041 14.1 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 OQS00060.1 - 0.029 14.6 0.0 0.06 13.6 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GTP_EFTU PF00009.27 OQS00061.1 - 4.4e-24 85.1 0.1 8e-24 84.2 0.1 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 OQS00061.1 - 4.8e-05 23.4 0.1 0.0001 22.4 0.1 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 OQS00061.1 - 0.0025 17.4 0.6 0.8 9.2 0.1 2.5 2 0 0 2 2 2 2 Ferrous iron transport protein B RsgA_GTPase PF03193.16 OQS00061.1 - 0.0039 17.1 0.9 0.2 11.5 0.1 2.3 2 0 0 2 2 2 1 RsgA GTPase GTP_EFTU_D2 PF03144.25 OQS00061.1 - 0.0065 16.8 0.0 0.018 15.4 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MeaB PF03308.16 OQS00061.1 - 0.013 14.5 0.2 1.3 7.9 0.1 2.2 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Tim44 PF04280.15 OQS00062.1 - 0.0069 16.5 0.6 0.13 12.3 0.6 2.2 1 1 0 1 1 1 1 Tim44-like domain Es2 PF09751.9 OQS00063.1 - 2.7e-56 192.2 16.4 9.4e-45 154.1 8.9 2.0 1 1 1 2 2 2 2 Nuclear protein Es2 ZapC PF07126.12 OQS00063.1 - 0.04 13.5 0.5 2.4 7.7 0.0 2.5 1 1 1 2 2 2 0 Cell-division protein ZapC PEPCK_GTP PF00821.18 OQS00064.1 - 0.086 11.6 0.3 0.25 10.1 0.0 1.7 1 1 0 2 2 2 0 Phosphoenolpyruvate carboxykinase C-terminal P-loop domain HTH_Tnp_Tc5 PF03221.16 OQS00065.1 - 1.3e-12 47.5 0.0 5.6e-12 45.5 0.0 2.0 1 1 1 2 2 2 1 Tc5 transposase DNA-binding domain PPR_long PF17177.4 OQS00066.1 - 7.7e-05 22.1 2.9 0.00065 19.1 0.1 3.0 1 1 2 3 3 3 1 Pentacotripeptide-repeat region of PRORP TPR_7 PF13176.6 OQS00066.1 - 0.007 16.3 0.4 8.6 6.6 0.1 3.5 4 0 0 4 4 4 1 Tetratricopeptide repeat PPR PF01535.20 OQS00066.1 - 0.013 15.7 0.2 33 5.0 0.0 4.8 6 0 0 6 6 6 0 PPR repeat Methyltransf_32 PF13679.6 OQS00066.1 - 0.027 14.5 0.8 1.1 9.3 0.0 3.1 3 1 0 3 3 3 0 Methyltransferase domain Methyltransf_12 PF08242.12 OQS00066.1 - 0.052 14.3 0.0 1.6 9.6 0.0 2.8 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_31 PF13847.6 OQS00066.1 - 0.059 13.2 0.1 0.24 11.2 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase domain Synthase_beta PF11421.8 OQS00066.1 - 0.066 13.9 4.0 0.2 12.4 4.0 1.9 1 0 0 1 1 1 0 ATP synthase F1 beta subunit BTAD PF03704.17 OQS00066.1 - 0.075 13.5 0.0 10 6.6 0.0 2.8 2 0 0 2 2 2 0 Bacterial transcriptional activator domain TPR_1 PF00515.28 OQS00066.1 - 0.36 10.7 1.3 21 5.1 0.2 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat ATP13 PF12921.7 OQS00066.1 - 0.42 10.5 1.9 68 3.4 0.0 3.9 4 2 0 4 4 4 0 Mitochondrial ATPase expression TPR_6 PF13174.6 OQS00066.1 - 0.57 10.9 6.6 26 5.8 0.0 4.7 5 0 0 5 5 5 0 Tetratricopeptide repeat Pyr_redox_2 PF07992.14 OQS00067.1 - 9.6e-10 38.2 0.0 2.4e-09 36.9 0.0 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 OQS00067.1 - 0.00013 21.2 0.0 0.00045 19.5 0.0 1.8 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 OQS00067.1 - 0.00028 20.2 3.1 0.3 10.3 0.1 3.1 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 OQS00067.1 - 0.028 14.0 3.7 3.6 7.1 0.0 3.0 2 1 1 3 3 3 0 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 OQS00067.1 - 0.56 10.2 1.9 5.9 6.9 1.9 2.4 1 1 0 1 1 1 0 FAD-NAD(P)-binding RAI16-like PF10257.9 OQS00068.1 - 3.1e-39 134.9 0.6 5.4e-39 134.1 0.6 1.4 1 0 0 1 1 1 1 Retinoic acid induced 16-like protein PKS_DE PF18369.1 OQS00068.1 - 0.032 14.8 0.3 0.2 12.2 0.1 2.5 2 0 0 2 2 2 0 Polyketide synthase dimerisation element domain DHC_N2 PF08393.13 OQS00069.1 - 3.2e-51 174.7 14.6 3.2e-51 174.7 14.6 2.9 2 0 0 2 2 2 1 Dynein heavy chain, N-terminal region 2 AAA_6 PF12774.7 OQS00069.1 - 2.2e-33 115.6 1.8 6.7e-33 114.0 1.8 2.0 1 0 0 1 1 1 1 Hydrolytic ATP binding site of dynein motor region AAA_7 PF12775.7 OQS00069.1 - 1.3e-30 106.3 0.7 2e-27 95.9 0.0 4.1 4 0 0 4 4 4 1 P-loop containing dynein motor region MT PF12777.7 OQS00069.1 - 1e-27 97.1 0.3 2.1e-27 96.1 0.3 1.5 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_8 PF12780.7 OQS00069.1 - 5.2e-22 78.4 0.1 2.7e-19 69.5 0.0 2.7 2 0 0 2 2 2 2 P-loop containing dynein motor region D4 Dynein_C PF18199.1 OQS00069.1 - 6.5e-11 42.0 0.5 1.9e-10 40.4 0.5 1.8 1 0 0 1 1 1 1 Dynein heavy chain C-terminal domain Dynein_AAA_lid PF17852.1 OQS00069.1 - 8.6e-10 38.8 1.4 3e-09 37.0 0.2 2.8 2 0 0 2 2 1 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 OQS00069.1 - 5.6e-05 23.2 0.0 0.00055 20.0 0.0 2.8 1 0 0 1 1 1 1 Dynein heavy chain region D6 P-loop domain AAA_22 PF13401.6 OQS00069.1 - 7.9e-05 22.9 1.2 0.011 16.0 0.0 4.2 4 0 0 4 4 4 1 AAA domain AAA_16 PF13191.6 OQS00069.1 - 0.00011 22.6 0.2 0.29 11.5 0.0 4.6 4 0 0 4 4 3 1 AAA ATPase domain AAA_5 PF07728.14 OQS00069.1 - 0.00035 20.6 0.0 1.1 9.3 0.0 3.9 4 0 0 4 4 3 1 AAA domain (dynein-related subfamily) AAA_29 PF13555.6 OQS00069.1 - 0.00056 19.6 0.1 0.67 9.7 0.0 3.3 3 0 0 3 3 3 1 P-loop containing region of AAA domain DUF815 PF05673.13 OQS00069.1 - 0.0035 16.5 1.7 0.075 12.2 0.0 3.3 3 0 0 3 3 3 1 Protein of unknown function (DUF815) AAA_21 PF13304.6 OQS00069.1 - 0.0075 16.1 0.2 0.048 13.5 0.0 2.4 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA PF00004.29 OQS00069.1 - 0.014 15.8 0.4 9.6 6.6 0.1 3.7 3 0 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.27 OQS00069.1 - 0.016 15.8 0.2 22 5.6 0.0 4.4 4 0 0 4 4 4 0 ABC transporter Rad17 PF03215.15 OQS00069.1 - 0.019 14.9 0.0 1.4 8.8 0.0 3.0 2 0 0 2 2 2 0 Rad17 P-loop domain Sigma54_activat PF00158.26 OQS00069.1 - 0.08 12.6 0.1 6 6.5 0.0 3.4 3 0 0 3 3 3 0 Sigma-54 interaction domain GST_N_3 PF13417.6 OQS00070.1 - 1.2e-06 28.9 0.0 2.2e-06 27.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 OQS00070.1 - 1.2e-05 25.3 0.0 3.2e-05 23.9 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 OQS00070.1 - 0.017 15.3 0.0 0.036 14.3 0.0 1.7 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain TB2_DP1_HVA22 PF03134.19 OQS00071.1 - 1.3e-20 73.1 1.8 2.2e-20 72.3 1.8 1.4 1 0 0 1 1 1 1 TB2/DP1, HVA22 family DUF294_C PF10335.9 OQS00071.1 - 0.011 15.5 0.2 0.04 13.7 0.2 1.9 2 0 0 2 2 2 0 Putative nucleotidyltransferase substrate binding domain Nucleo_P87 PF07267.11 OQS00071.1 - 0.13 11.1 1.8 0.18 10.7 1.8 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Mito_fiss_reg PF05308.11 OQS00071.1 - 0.31 11.1 5.5 0.45 10.6 5.5 1.2 1 0 0 1 1 1 0 Mitochondrial fission regulator RRM_1 PF00076.22 OQS00072.1 - 9.3e-12 44.6 0.0 1.6e-11 43.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) YjfB_motility PF14070.6 OQS00073.1 - 0.054 13.7 0.9 0.084 13.0 0.9 1.3 1 0 0 1 1 1 0 Putative motility protein DHC PF09626.10 OQS00073.1 - 0.11 13.4 0.1 0.16 12.9 0.1 1.2 1 0 0 1 1 1 0 Dihaem cytochrome c BT1 PF03092.16 OQS00074.1 - 2.5e-11 42.5 1.0 2.5e-11 42.5 1.0 1.3 2 0 0 2 2 2 1 BT1 family PUCC PF03209.15 OQS00074.1 - 0.0041 16.2 0.4 0.01 14.9 0.4 1.6 1 1 0 1 1 1 1 PUCC protein MFS_1 PF07690.16 OQS00074.1 - 0.007 15.3 3.6 0.007 15.3 3.6 1.8 2 0 0 2 2 2 1 Major Facilitator Superfamily UL42 PF17638.2 OQS00074.1 - 0.036 14.0 0.6 0.093 12.7 0.6 1.6 1 1 0 1 1 1 0 HCMV UL42 OppC_N PF12911.7 OQS00074.1 - 0.049 13.6 0.0 0.12 12.4 0.0 1.6 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C Methyltr_RsmB-F PF01189.17 OQS00075.1 - 4.6e-28 98.2 0.0 5.4e-28 98.0 0.0 1.0 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F FtsJ PF01728.19 OQS00075.1 - 0.051 13.7 0.0 0.062 13.4 0.0 1.5 1 1 0 1 1 1 0 FtsJ-like methyltransferase CSRNP_N PF16019.5 OQS00076.1 - 0.0051 16.8 0.3 0.013 15.4 0.3 1.6 1 1 0 1 1 1 1 Cysteine/serine-rich nuclear protein N-terminus Sua5_yciO_yrdC PF01300.18 OQS00077.1 - 1.6e-46 158.1 0.0 2.3e-46 157.5 0.0 1.2 1 0 0 1 1 1 1 Telomere recombination SUA5 PF03481.13 OQS00077.1 - 7.8e-13 49.1 0.0 1.3e-12 48.4 0.0 1.4 1 0 0 1 1 1 1 Putative GTP-binding controlling metal-binding UBX PF00789.20 OQS00078.1 - 1.7e-16 60.2 0.0 3.1e-16 59.4 0.0 1.4 1 0 0 1 1 1 1 UBX domain ARGLU PF15346.6 OQS00078.1 - 0.0062 16.4 24.9 0.01 15.7 24.9 1.3 1 0 0 1 1 1 1 Arginine and glutamate-rich 1 AAA_12 PF13087.6 OQS00078.1 - 0.014 15.0 2.1 0.023 14.3 2.1 1.4 1 0 0 1 1 1 0 AAA domain FAM60A PF15396.6 OQS00078.1 - 0.24 11.4 2.5 0.36 10.8 2.5 1.2 1 0 0 1 1 1 0 Protein Family FAM60A MCD PF05292.11 OQS00078.1 - 1.2 8.7 5.8 0.53 9.8 3.1 1.7 2 1 0 2 2 2 0 Malonyl-CoA decarboxylase C-terminal domain Oscp1 PF10188.9 OQS00079.1 - 2.2e-66 223.3 8.6 2.9e-66 222.9 8.6 1.2 1 0 0 1 1 1 1 Organic solute transport protein 1 WW PF00397.26 OQS00080.1 - 4.3e-25 87.5 7.2 3.5e-12 46.2 0.5 2.4 2 0 0 2 2 2 2 WW domain FYVE PF01363.21 OQS00080.1 - 3.5e-13 49.5 7.4 3.5e-13 49.5 7.4 4.0 3 1 0 3 3 3 1 FYVE zinc finger HEAT_EZ PF13513.6 OQS00080.1 - 0.00066 20.1 0.1 0.98 10.0 0.0 5.2 4 0 0 4 4 4 1 HEAT-like repeat Arm PF00514.23 OQS00080.1 - 0.089 12.9 8.2 6.8 6.9 0.1 5.6 6 0 0 6 6 6 0 Armadillo/beta-catenin-like repeat DM13 PF10517.9 OQS00080.1 - 0.13 12.8 0.1 1.5 9.5 0.0 2.3 2 0 0 2 2 2 0 Electron transfer DM13 zinc_ribbon_5 PF13719.6 OQS00080.1 - 4.3 7.2 19.7 0.62 9.9 3.3 4.1 4 0 0 4 4 4 0 zinc-ribbon domain Ion_trans PF00520.31 OQS00081.1 - 1.1e-89 299.8 59.2 8e-36 123.5 22.7 3.1 3 0 0 3 3 3 3 Ion transport protein PKD_channel PF08016.12 OQS00081.1 - 0.0018 17.1 8.7 0.0018 17.1 8.7 5.9 6 1 1 7 7 7 3 Polycystin cation channel Sarcoglycan_1 PF04790.13 OQS00081.1 - 0.095 12.0 0.1 0.22 10.8 0.1 1.5 1 0 0 1 1 1 0 Sarcoglycan complex subunit protein Notch PF00066.17 OQS00082.1 - 5.3e-05 23.6 12.8 0.00012 22.5 12.8 1.6 1 0 0 1 1 1 1 LNR domain LRR_8 PF13855.6 OQS00082.1 - 5.9 6.7 9.5 1.8 8.4 0.2 4.0 3 1 3 6 6 6 0 Leucine rich repeat PP2C PF00481.21 OQS00083.1 - 2.1e-34 119.3 0.0 4.6e-34 118.2 0.0 1.5 1 0 0 1 1 1 1 Protein phosphatase 2C Prominin PF05478.11 OQS00083.1 - 1.4e-06 26.6 0.4 1.4e-06 26.6 0.4 3.0 3 0 0 3 3 3 2 Prominin Ank_5 PF13857.6 OQS00083.1 - 0.0038 17.5 0.1 0.59 10.5 0.0 2.8 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 OQS00083.1 - 0.0063 17.1 0.2 0.3 11.7 0.0 3.1 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 OQS00083.1 - 0.016 15.8 0.0 0.054 14.1 0.0 2.0 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) PigN PF04987.14 OQS00084.1 - 1.4e-92 311.0 46.8 1.9e-92 310.5 46.8 1.2 1 0 0 1 1 1 1 Phosphatidylinositolglycan class N (PIG-N) Phosphodiest PF01663.22 OQS00084.1 - 8.6e-10 38.7 1.6 3e-06 27.1 0.4 2.7 1 1 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 OQS00084.1 - 1.8e-07 30.8 0.1 2.8e-07 30.2 0.1 1.2 1 0 0 1 1 1 1 Sulfatase PglZ PF08665.12 OQS00084.1 - 0.18 11.9 0.1 0.45 10.6 0.1 1.6 2 0 0 2 2 2 0 PglZ domain LRR_6 PF13516.6 OQS00085.1 - 1.2e-16 59.3 23.5 0.041 13.9 0.6 9.2 9 0 0 9 9 9 7 Leucine Rich repeat DUF4476 PF14771.6 OQS00085.1 - 3.1e-06 27.4 5.1 0.041 14.2 0.1 3.6 3 0 0 3 3 3 2 Domain of unknown function (DUF4476) LRR_4 PF12799.7 OQS00085.1 - 7.4e-05 23.0 11.9 0.13 12.7 3.7 4.9 4 1 0 4 4 4 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 OQS00085.1 - 0.0092 16.4 14.1 0.91 10.3 0.2 6.3 7 1 0 7 7 7 2 Leucine Rich Repeat LRR_8 PF13855.6 OQS00085.1 - 4.2 7.2 16.4 34 4.3 5.0 5.2 3 1 1 4 4 4 0 Leucine rich repeat zf-SNAP50_C PF12251.8 OQS00086.1 - 5e-20 72.0 0.8 1.1e-19 70.9 0.8 1.5 1 0 0 1 1 1 1 snRNA-activating protein of 50kDa MW C terminal GpcrRhopsn4 PF10192.9 OQS00087.1 - 1.4e-11 44.3 2.1 1.4e-11 44.3 2.1 2.7 3 0 0 3 3 3 1 Rhodopsin-like GPCR transmembrane domain Lung_7-TM_R PF06814.13 OQS00087.1 - 9.2e-08 31.7 15.6 4.1e-06 26.3 15.6 2.3 1 1 0 1 1 1 1 Lung seven transmembrane receptor FtsK_4TM PF13491.6 OQS00087.1 - 1.1 9.0 7.0 0.67 9.6 0.9 2.7 1 1 1 2 2 2 0 4TM region of DNA translocase FtsK/SpoIIIE DUF996 PF06195.13 OQS00087.1 - 8.4 6.7 9.1 1.5 9.1 0.1 2.9 4 0 0 4 4 4 0 Protein of unknown function (DUF996) Ank_2 PF12796.7 OQS00088.1 - 3.6e-14 53.1 3.7 4.3e-05 24.0 0.4 3.3 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQS00088.1 - 2.6e-11 43.8 4.6 1.5e-05 25.5 0.1 4.5 2 2 4 6 6 6 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 OQS00088.1 - 2.3e-10 40.5 2.3 0.0077 16.5 0.0 5.1 1 1 4 5 5 5 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQS00088.1 - 2.2e-08 33.7 0.5 6.2 7.7 0.0 5.9 6 1 1 7 7 7 2 Ankyrin repeat Guanylate_cyc_2 PF09778.9 OQS00089.1 - 1.8e-38 132.1 2.6 2.5e-38 131.6 2.6 1.2 1 0 0 1 1 1 1 Guanylylate cyclase Peptidase_C70 PF12385.8 OQS00089.1 - 1.8e-05 24.8 0.3 0.021 14.8 0.0 2.1 2 0 0 2 2 2 2 Papain-like cysteine protease AvrRpt2 Peptidase_C39 PF03412.15 OQS00089.1 - 0.0022 17.8 0.1 1.8 8.3 0.0 2.4 2 0 0 2 2 2 2 Peptidase C39 family Herpes_TAF50 PF03326.13 OQS00089.1 - 0.31 9.7 0.3 0.47 9.1 0.3 1.2 1 0 0 1 1 1 0 Herpesvirus transcription activation factor (transactivator) Peptidase_C1 PF00112.23 OQS00090.1 - 2.8e-85 285.9 22.5 1.1e-59 202.2 9.7 2.4 2 0 0 2 2 2 2 Papain family cysteine protease VHS PF00790.19 OQS00090.1 - 5.8e-25 87.8 0.0 1.4e-24 86.5 0.0 1.7 1 0 0 1 1 1 1 VHS domain AMP-binding PF00501.28 OQS00090.1 - 1.3e-14 53.6 0.0 9.2e-09 34.4 0.0 2.3 2 0 0 2 2 2 2 AMP-binding enzyme GAT PF03127.14 OQS00090.1 - 4.5e-11 42.9 2.4 1.3e-10 41.4 2.4 1.8 1 0 0 1 1 1 1 GAT domain Peptidase_C1_2 PF03051.15 OQS00090.1 - 0.85 8.3 5.6 7.7 5.2 0.2 3.0 3 0 0 3 3 3 0 Peptidase C1-like family Ank_2 PF12796.7 OQS00091.1 - 8.9e-64 212.1 11.5 8.5e-13 48.7 0.0 8.0 4 3 4 8 8 8 8 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OQS00091.1 - 2.2e-52 174.4 20.6 3.7e-05 23.9 0.0 14.0 7 4 7 14 14 14 12 Ankyrin repeats (many copies) Ank_4 PF13637.6 OQS00091.1 - 9.5e-50 166.4 11.9 1.5e-07 31.8 0.0 11.2 9 3 2 11 11 11 8 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQS00091.1 - 3e-40 131.6 26.1 0.0014 18.9 0.2 15.4 16 0 0 16 16 16 10 Ankyrin repeat Ank PF00023.30 OQS00091.1 - 5.5e-38 127.8 25.3 0.003 17.9 0.1 13.4 13 1 1 14 14 14 9 Ankyrin repeat IBR PF01485.21 OQS00092.1 - 0.00084 19.5 6.2 0.00084 19.5 6.2 11.2 11 2 0 11 11 11 4 IBR domain, a half RING-finger domain WD40 PF00400.32 OQS00093.1 - 1.8e-34 117.1 11.1 1.1e-05 26.0 0.0 9.6 9 0 0 9 9 9 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OQS00093.1 - 5e-22 78.0 1.2 0.024 14.9 0.1 8.5 5 2 3 8 8 8 5 Anaphase-promoting complex subunit 4 WD40 domain PQQ_2 PF13360.6 OQS00093.1 - 3.2e-05 23.6 0.3 0.0053 16.4 0.3 2.6 2 0 0 2 2 2 2 PQQ-like domain Nup160 PF11715.8 OQS00093.1 - 0.00024 19.9 0.4 2.6 6.6 0.3 3.3 2 1 1 3 3 3 3 Nucleoporin Nup120/160 Cnn_1N PF07989.11 OQS00093.1 - 0.003 17.7 1.6 0.01 16.0 1.3 2.1 1 1 1 2 2 2 1 Centrosomin N-terminal motif 1 Ge1_WD40 PF16529.5 OQS00093.1 - 0.0054 15.7 0.0 3.6 6.5 0.0 3.9 3 2 2 5 5 5 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Sacchrp_dh_NADP PF03435.18 OQS00093.1 - 0.05 13.9 0.1 0.16 12.2 0.0 1.8 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain DUF3523 PF12037.8 OQS00094.1 - 5e-42 144.1 19.6 7.4e-42 143.6 19.6 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3523) AAA PF00004.29 OQS00094.1 - 2.4e-21 76.6 0.0 8e-21 74.8 0.0 2.0 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) 2OG-FeII_Oxy_3 PF13640.6 OQS00094.1 - 6.8e-10 39.7 0.1 2.3e-09 38.0 0.0 2.0 2 0 0 2 2 1 1 2OG-Fe(II) oxygenase superfamily RuvB_N PF05496.12 OQS00094.1 - 9.7e-06 25.4 0.0 3e-05 23.8 0.0 1.9 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 OQS00094.1 - 8.3e-05 22.9 0.5 0.0082 16.4 0.0 3.0 3 0 0 3 3 2 1 AAA domain Mg_chelatase PF01078.21 OQS00094.1 - 0.00017 21.1 0.1 0.0004 19.8 0.1 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 OQS00094.1 - 0.00035 20.6 0.2 0.004 17.2 0.1 2.7 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 OQS00094.1 - 0.00041 20.8 1.4 0.016 15.6 0.0 2.9 2 1 1 3 3 3 1 AAA ATPase domain AAA_25 PF13481.6 OQS00094.1 - 0.0014 18.3 0.0 0.37 10.4 0.0 2.8 1 1 0 2 2 2 1 AAA domain AAA_3 PF07726.11 OQS00094.1 - 0.012 15.4 0.1 0.06 13.2 0.0 2.2 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Zot PF05707.12 OQS00094.1 - 0.017 14.8 1.8 0.18 11.5 0.0 2.9 3 0 0 3 3 3 0 Zonular occludens toxin (Zot) AAA_24 PF13479.6 OQS00094.1 - 0.021 14.5 0.9 0.064 13.0 0.0 2.2 3 0 0 3 3 3 0 AAA domain MRF_C1 PF13887.6 OQS00094.1 - 0.069 12.3 0.0 0.22 10.7 0.0 1.8 1 0 0 1 1 1 0 Myelin gene regulatory factor -C-terminal domain 1 AAA_18 PF13238.6 OQS00094.1 - 0.089 13.3 1.6 0.23 12.0 0.0 2.6 2 1 0 2 2 2 0 AAA domain AAA_7 PF12775.7 OQS00094.1 - 0.11 12.0 0.0 0.23 11.0 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_11 PF13086.6 OQS00094.1 - 0.87 9.3 0.0 0.87 9.3 0.0 2.5 2 0 0 2 2 1 0 AAA domain IpaC_SipC PF09599.10 OQS00094.1 - 1.3 8.5 18.4 0.17 11.4 9.6 2.1 1 1 0 2 2 2 0 Salmonella-Shigella invasin protein C (IpaC_SipC) p450 PF00067.22 OQS00096.1 - 5.9e-79 266.0 0.0 7e-79 265.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Pkinase PF00069.25 OQS00097.1 - 1.4e-20 73.8 0.0 1.6e-20 73.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQS00097.1 - 5.3e-18 65.2 0.0 6.3e-18 65.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Arf PF00025.21 OQS00098.1 - 2.2e-70 235.6 0.8 2.5e-70 235.5 0.8 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 OQS00098.1 - 5.4e-14 52.4 0.1 7.7e-14 51.9 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 OQS00098.1 - 2e-11 43.8 0.0 2.3e-11 43.5 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.20 OQS00098.1 - 5.6e-11 42.2 2.9 2.3e-05 23.8 0.2 2.4 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.12 OQS00098.1 - 5.9e-10 38.9 0.0 6.7e-10 38.7 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 OQS00098.1 - 2.5e-09 36.8 0.0 3.3e-09 36.4 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 OQS00098.1 - 1.2e-06 28.6 0.0 2e-06 27.9 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 OQS00098.1 - 0.00016 21.3 0.0 0.001 18.7 0.0 1.7 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain TniB PF05621.11 OQS00098.1 - 0.018 14.4 0.2 0.039 13.4 0.1 1.6 2 0 0 2 2 2 0 Bacterial TniB protein PPK2 PF03976.14 OQS00098.1 - 0.33 10.4 1.4 0.89 9.0 0.2 2.0 2 0 0 2 2 2 0 Polyphosphate kinase 2 (PPK2) Clat_adaptor_s PF01217.20 OQS00099.1 - 1.6e-51 174.0 3.2 1.8e-51 173.8 3.2 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain p450 PF00067.22 OQS00100.1 - 4.1e-68 230.2 0.0 1.2e-67 228.7 0.0 1.6 1 1 0 1 1 1 1 Cytochrome P450 HTH_Tnp_Tc5 PF03221.16 OQS00102.1 - 6.8e-11 42.0 0.2 6.8e-11 42.0 0.2 2.0 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain DivIC PF04977.15 OQS00104.1 - 0.015 15.1 0.6 0.015 15.1 0.6 2.1 1 1 1 2 2 2 0 Septum formation initiator TMPIT PF07851.13 OQS00104.1 - 0.044 13.0 1.9 0.051 12.8 1.9 1.1 1 0 0 1 1 1 0 TMPIT-like protein YabA PF06156.13 OQS00104.1 - 0.37 11.5 4.0 0.53 11.0 4.0 1.4 1 0 0 1 1 1 0 Initiation control protein YabA JIP_LZII PF16471.5 OQS00104.1 - 0.45 10.7 10.3 2.6 8.3 0.9 2.2 1 1 1 2 2 2 0 JNK-interacting protein leucine zipper II UCH PF00443.29 OQS00105.1 - 1.3e-49 169.1 0.0 1.7e-49 168.7 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 OQS00105.1 - 6.9e-12 45.6 3.9 6.3e-10 39.2 3.9 2.8 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Peptidase_C98 PF15499.6 OQS00105.1 - 7.6e-05 22.3 0.0 0.0033 16.9 0.0 2.3 2 0 0 2 2 2 1 Ubiquitin-specific peptidase-like, SUMO isopeptidase ubiquitin PF00240.23 OQS00105.1 - 0.00051 19.7 0.0 0.00096 18.9 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family Cutinase PF01083.22 OQS00106.1 - 1.7e-42 145.4 2.3 2.1e-42 145.1 2.3 1.1 1 0 0 1 1 1 1 Cutinase Lipase_3 PF01764.25 OQS00106.1 - 0.0061 16.4 0.0 0.011 15.7 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) zf-C2H2_jaz PF12171.8 OQS00107.1 - 5e-06 26.6 0.2 5e-06 26.6 0.2 1.7 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 OQS00107.1 - 0.0011 19.3 0.2 0.0024 18.2 0.2 1.6 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_3rep PF18868.1 OQS00107.1 - 0.01 16.5 0.1 0.019 15.6 0.1 1.5 1 1 0 1 1 1 1 Zinc finger C2H2-type, 3 repeats zf-C2H2_2 PF12756.7 OQS00107.1 - 0.016 15.5 1.2 0.019 15.3 0.5 1.5 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) PRELI PF04707.14 OQS00108.1 - 8.4e-36 123.2 0.0 9.7e-36 123.0 0.0 1.0 1 0 0 1 1 1 1 PRELI-like family Gluconate_2-dh3 PF13618.6 OQS00108.1 - 0.039 14.2 0.0 0.06 13.6 0.0 1.3 1 0 0 1 1 1 0 Gluconate 2-dehydrogenase subunit 3 DUF2505 PF10698.9 OQS00108.1 - 0.069 13.3 0.0 0.11 12.6 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2505) MS_channel PF00924.18 OQS00109.1 - 1.1e-19 70.8 0.4 2e-19 69.9 0.4 1.5 1 0 0 1 1 1 1 Mechanosensitive ion channel Pkinase PF00069.25 OQS00110.1 - 4.2e-50 170.6 0.0 6.3e-50 170.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQS00110.1 - 9.7e-50 169.3 0.0 1.5e-49 168.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase HEAT PF02985.22 OQS00110.1 - 4e-21 73.3 11.5 4.7e-05 23.3 0.1 8.9 8 0 0 8 8 8 5 HEAT repeat HEAT_2 PF13646.6 OQS00110.1 - 7.4e-13 48.7 0.2 0.008 16.5 0.0 6.2 4 2 1 5 5 5 3 HEAT repeats Vac14_Fab1_bd PF12755.7 OQS00110.1 - 0.00011 22.7 0.1 0.0041 17.7 0.0 3.4 3 1 0 4 4 4 1 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.6 OQS00110.1 - 0.0093 16.5 2.7 0.34 11.5 0.0 4.4 4 1 1 5 5 5 1 HEAT-like repeat Pkinase_fungal PF17667.1 OQS00110.1 - 0.022 13.6 0.2 0.034 12.9 0.2 1.2 1 0 0 1 1 1 0 Fungal protein kinase Haspin_kinase PF12330.8 OQS00110.1 - 0.031 13.2 0.1 0.12 11.3 0.0 1.9 2 0 0 2 2 2 0 Haspin like kinase domain CLASP_N PF12348.8 OQS00110.1 - 0.12 12.0 0.0 2.1 7.9 0.0 2.9 3 1 0 4 4 4 0 CLASP N terminal DEAD PF00270.29 OQS00111.1 - 3.1e-47 160.6 0.0 6.8e-47 159.5 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OQS00111.1 - 1.9e-28 99.0 0.0 8.3e-28 97.0 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 OQS00111.1 - 0.00029 20.9 0.0 0.0015 18.6 0.0 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 OQS00111.1 - 0.2 12.0 0.9 2.5 8.4 0.9 2.5 1 1 0 1 1 1 0 AAA domain DUF2098 PF09871.9 OQS00111.1 - 1.2 9.5 3.6 0.42 11.0 0.2 1.9 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2098) Oxidored_FMN PF00724.20 OQS00112.1 - 2.2e-86 290.2 0.0 2.9e-86 289.8 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Pyr_redox_2 PF07992.14 OQS00112.1 - 2e-22 79.8 2.9 6.3e-22 78.2 2.9 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OQS00112.1 - 2e-08 34.3 0.1 1.7e-07 31.4 0.1 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 OQS00112.1 - 5.2e-08 33.3 2.4 0.0032 18.0 0.2 3.7 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 OQS00112.1 - 6.9e-07 28.8 2.2 0.011 15.0 0.1 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 OQS00112.1 - 1.8e-06 26.9 0.7 1.8e-06 26.9 0.7 1.9 2 0 0 2 2 2 1 HI0933-like protein FAD_oxidored PF12831.7 OQS00112.1 - 5.8e-06 25.9 0.9 9e-06 25.3 0.9 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 OQS00112.1 - 2.2e-05 23.9 0.8 0.00031 20.1 0.1 2.6 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_2 PF00890.24 OQS00112.1 - 2.3e-05 23.7 1.0 5.1e-05 22.5 1.0 1.6 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 OQS00112.1 - 0.0004 20.1 0.5 0.0004 20.1 0.5 4.0 4 1 1 5 5 5 1 FAD dependent oxidoreductase Thi4 PF01946.17 OQS00112.1 - 0.00049 19.4 0.2 0.002 17.4 0.0 1.9 2 0 0 2 2 2 1 Thi4 family 2-Hacid_dh_C PF02826.19 OQS00112.1 - 0.00057 19.3 2.6 0.62 9.4 0.1 3.4 3 0 0 3 3 3 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain GIDA PF01134.22 OQS00112.1 - 0.0018 17.4 0.8 0.0042 16.2 0.2 1.9 2 0 0 2 2 2 1 Glucose inhibited division protein A 3HCDH_N PF02737.18 OQS00112.1 - 0.0036 17.2 3.0 0.026 14.4 0.1 2.5 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_binding_3 PF01494.19 OQS00112.1 - 0.0084 15.4 0.2 0.0084 15.4 0.2 1.8 2 0 0 2 2 2 1 FAD binding domain UDPG_MGDP_dh_N PF03721.14 OQS00112.1 - 0.012 15.2 0.6 0.069 12.7 0.0 2.2 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_Gly3P_dh_N PF01210.23 OQS00112.1 - 0.017 15.1 0.4 0.17 11.9 0.0 2.4 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus FMO-like PF00743.19 OQS00112.1 - 0.019 13.4 0.0 0.15 10.4 0.0 2.0 2 0 0 2 2 2 0 Flavin-binding monooxygenase-like PglD_N PF17836.1 OQS00112.1 - 0.046 14.4 1.0 6.3 7.5 0.1 2.9 2 0 0 2 2 2 0 PglD N-terminal domain UDG PF03167.19 OQS00113.1 - 0.009 16.0 0.0 0.067 13.2 0.0 2.2 1 1 0 1 1 1 1 Uracil DNA glycosylase superfamily Guanylate_cyc PF00211.20 OQS00114.1 - 3.6e-09 36.5 0.1 8.5e-09 35.3 0.0 1.6 2 0 0 2 2 2 1 Adenylate and Guanylate cyclase catalytic domain DUF1129 PF06570.11 OQS00114.1 - 1.3 8.5 5.2 0.18 11.2 0.8 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) DUF1077 PF06417.12 OQS00114.1 - 1.7 8.7 4.2 27 4.8 0.1 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1077) Mito_carr PF00153.27 OQS00115.1 - 7.9e-63 208.4 1.7 3.8e-22 78.0 0.1 3.7 3 1 0 3 3 3 3 Mitochondrial carrier protein ubiquitin PF00240.23 OQS00116.1 - 2e-07 30.6 0.4 5.5e-07 29.3 0.4 1.6 1 1 0 1 1 1 1 Ubiquitin family Ubiquitin_2 PF14560.6 OQS00116.1 - 7.1e-05 23.2 0.1 0.00031 21.1 0.1 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain Rad60-SLD PF11976.8 OQS00116.1 - 0.0027 17.5 0.5 0.018 14.9 0.5 1.9 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_4 PF18036.1 OQS00116.1 - 0.016 15.2 0.4 0.079 13.0 0.4 1.9 1 1 0 1 1 1 0 Ubiquitin-like domain RAWUL PF16207.5 OQS00116.1 - 0.054 14.2 0.0 0.07 13.8 0.0 1.2 1 0 0 1 1 1 0 RAWUL domain RING finger- and WD40-associated ubiquitin-like PAN_4 PF14295.6 OQS00117.1 - 7e-20 70.7 33.5 3.2e-08 33.3 5.1 4.4 5 0 0 5 5 5 3 PAN domain PAN_1 PF00024.26 OQS00117.1 - 3e-07 30.3 20.3 0.0018 18.2 0.9 3.6 1 1 2 3 3 3 3 PAN domain MANEC PF07502.14 OQS00117.1 - 2.8 8.3 23.7 1.5 9.1 2.0 3.3 2 1 1 3 3 3 0 MANEC domain CH PF00307.31 OQS00118.1 - 8.6e-07 29.1 0.0 2.2e-06 27.8 0.0 1.8 1 1 0 1 1 1 1 Calponin homology (CH) domain CAMSAP_CH PF11971.8 OQS00118.1 - 0.00038 20.2 0.1 0.0042 16.9 0.0 2.1 2 0 0 2 2 2 1 CAMSAP CH domain CH_2 PF06294.11 OQS00118.1 - 0.11 12.7 0.0 0.18 11.9 0.0 1.5 1 1 0 1 1 1 0 CH-like domain in sperm protein Thi4 PF01946.17 OQS00119.1 - 0.00069 18.9 0.7 0.00093 18.5 0.7 1.1 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.24 OQS00119.1 - 0.001 18.2 0.0 0.0011 18.1 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 OQS00119.1 - 0.0025 18.0 0.2 0.0036 17.5 0.2 1.3 1 1 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 OQS00119.1 - 0.04 13.1 0.0 0.04 13.1 0.0 1.1 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 OQS00119.1 - 0.17 11.1 0.3 0.16 11.2 0.3 1.2 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 OQS00119.1 - 0.22 10.7 0.4 0.28 10.4 0.4 1.1 1 0 0 1 1 1 0 FAD binding domain Hydrolase_4 PF12146.8 OQS00120.1 - 1.3e-51 175.2 0.0 1.6e-51 174.9 0.0 1.1 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 OQS00120.1 - 1.3e-12 47.9 0.1 2.1e-08 34.1 0.1 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 OQS00120.1 - 5.9e-12 46.7 0.0 7.9e-12 46.3 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 OQS00120.1 - 2.3e-05 24.0 0.0 0.0002 20.9 0.0 2.0 2 0 0 2 2 2 1 Prolyl oligopeptidase family Esterase PF00756.20 OQS00120.1 - 0.0032 17.2 0.1 0.024 14.3 0.1 1.9 1 1 0 1 1 1 1 Putative esterase PhoPQ_related PF10142.9 OQS00120.1 - 0.0045 15.7 0.0 0.0065 15.2 0.0 1.2 1 0 0 1 1 1 1 PhoPQ-activated pathogenicity-related protein Peptidase_S15 PF02129.18 OQS00120.1 - 0.0055 16.3 0.0 0.61 9.6 0.0 2.1 2 0 0 2 2 2 2 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_2 PF02230.16 OQS00120.1 - 0.0065 16.3 0.0 5 6.9 0.0 3.0 3 0 0 3 3 3 1 Phospholipase/Carboxylesterase DUF1100 PF06500.11 OQS00120.1 - 0.015 14.1 0.0 0.048 12.4 0.0 1.7 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF1100) Oxidored_q3 PF00499.20 OQS00121.1 - 5.4 6.7 16.9 0.045 13.5 4.9 2.9 2 1 0 2 2 2 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 BLOC1_2 PF10046.9 OQS00122.1 - 4.6e-15 55.7 7.0 5.8e-15 55.4 7.0 1.1 1 0 0 1 1 1 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 Spc7 PF08317.11 OQS00122.1 - 8.3e-05 21.6 6.6 9.5e-05 21.4 6.6 1.1 1 0 0 1 1 1 1 Spc7 kinetochore protein FapA PF03961.13 OQS00122.1 - 0.014 14.0 3.5 0.015 13.9 3.5 1.0 1 0 0 1 1 1 0 Flagellar Assembly Protein A Metalloenzyme PF01676.18 OQS00122.1 - 0.021 14.2 1.0 0.024 14.0 1.0 1.0 1 0 0 1 1 1 0 Metalloenzyme superfamily CHDCT2 PF08074.11 OQS00122.1 - 0.022 14.9 2.6 0.14 12.3 0.4 2.1 1 1 1 2 2 2 0 CHDCT2 (NUC038) domain UPF0242 PF06785.11 OQS00122.1 - 0.025 14.7 7.3 0.03 14.4 7.3 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus COG5 PF10392.9 OQS00122.1 - 0.032 14.4 2.4 0.23 11.6 0.5 2.2 1 1 1 2 2 2 0 Golgi transport complex subunit 5 NAGidase PF07555.13 OQS00122.1 - 0.033 13.5 0.8 0.034 13.5 0.8 1.1 1 0 0 1 1 1 0 beta-N-acetylglucosaminidase DUF4446 PF14584.6 OQS00122.1 - 0.06 13.3 2.9 0.082 12.9 2.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) Polo_box_3 PF18544.1 OQS00122.1 - 0.063 13.9 1.2 0.11 13.1 0.9 1.5 1 1 0 1 1 1 0 Polo box domain DUF1664 PF07889.12 OQS00122.1 - 0.066 13.3 5.2 0.35 10.9 4.4 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) REV1_C PF16727.5 OQS00122.1 - 0.07 13.5 0.9 0.12 12.7 0.9 1.6 1 1 0 1 1 1 0 DNA repair protein REV1 C-terminal domain Mod_r PF07200.13 OQS00122.1 - 0.081 13.0 6.4 0.12 12.5 6.4 1.3 1 0 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein V-SNARE PF05008.15 OQS00122.1 - 0.099 13.0 5.3 0.11 12.9 3.3 2.0 1 1 0 2 2 2 0 Vesicle transport v-SNARE protein N-terminus DASH_Dam1 PF08653.10 OQS00122.1 - 0.13 12.1 1.6 1.8 8.5 0.3 2.5 1 1 0 2 2 2 0 DASH complex subunit Dam1 Exonuc_VII_L PF02601.15 OQS00122.1 - 0.27 10.7 2.6 0.3 10.6 2.6 1.0 1 0 0 1 1 1 0 Exonuclease VII, large subunit TMF_TATA_bd PF12325.8 OQS00122.1 - 0.3 11.3 10.5 0.44 10.8 10.5 1.4 1 1 0 1 1 1 0 TATA element modulatory factor 1 TATA binding CLZ PF16526.5 OQS00122.1 - 0.5 10.8 7.9 0.81 10.1 2.9 2.3 1 1 1 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF2205 PF10224.9 OQS00122.1 - 1.4 9.0 7.1 3.1 7.9 1.9 2.3 1 1 1 2 2 2 0 Short coiled-coil protein SlyX PF04102.12 OQS00122.1 - 6.2 7.5 9.1 2.1 9.0 4.4 2.3 2 1 1 3 3 2 0 SlyX GMC_oxred_N PF00732.19 OQS00123.1 - 9.3e-10 38.4 0.1 1.2e-09 38.0 0.1 1.1 1 0 0 1 1 1 1 GMC oxidoreductase CAF1C_H4-bd PF12265.8 OQS00124.1 - 1.7e-15 57.0 0.1 2.3e-14 53.4 0.0 2.5 2 0 0 2 2 2 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex WD40 PF00400.32 OQS00124.1 - 1e-14 54.6 18.6 2.2e-05 25.1 0.1 5.3 6 0 0 6 6 5 3 WD domain, G-beta repeat Methyltransf_31 PF13847.6 OQS00124.1 - 3.7e-11 43.1 0.3 6.4e-10 39.0 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 OQS00124.1 - 4.7e-11 43.2 0.0 1.6e-10 41.6 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OQS00124.1 - 2.5e-09 37.6 0.0 7.5e-09 36.1 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain ANAPC4_WD40 PF12894.7 OQS00124.1 - 8.9e-08 32.3 0.7 0.036 14.4 0.0 3.4 1 1 2 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain CMAS PF02353.20 OQS00124.1 - 6.4e-05 22.4 0.0 0.00011 21.6 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.6 OQS00124.1 - 0.00025 20.9 0.0 0.00051 19.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OQS00124.1 - 0.00063 20.4 0.0 0.0021 18.8 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.11 OQS00124.1 - 0.027 13.4 0.0 0.21 10.5 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1698) Methyltransf_18 PF12847.7 OQS00124.1 - 0.072 13.0 0.1 0.14 12.1 0.1 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_15 PF09445.10 OQS00124.1 - 0.087 12.4 0.0 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase GMC_oxred_N PF00732.19 OQS00125.1 - 1.5e-26 93.5 0.6 3.2e-25 89.1 0.6 2.6 1 1 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 OQS00125.1 - 1.7e-08 35.1 0.1 4.3e-08 33.8 0.1 1.6 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 OQS00125.1 - 3.8e-08 32.8 0.2 2.3e-05 23.7 0.2 2.4 2 0 0 2 2 2 2 FAD binding domain Thi4 PF01946.17 OQS00125.1 - 3e-06 26.6 0.2 1.3e-05 24.5 0.2 1.8 2 0 0 2 2 2 1 Thi4 family NAD_binding_8 PF13450.6 OQS00125.1 - 2.3e-05 24.5 1.1 0.00011 22.3 0.2 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 OQS00125.1 - 0.00012 21.5 0.0 0.00025 20.4 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 OQS00125.1 - 0.00013 21.7 1.5 0.0011 18.6 0.5 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.14 OQS00125.1 - 0.0042 15.8 0.1 0.0091 14.7 0.1 1.5 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_3 PF01494.19 OQS00125.1 - 0.011 15.0 0.2 0.018 14.3 0.2 1.3 1 0 0 1 1 1 0 FAD binding domain Lycopene_cycl PF05834.12 OQS00125.1 - 0.038 13.0 1.7 0.047 12.7 0.3 1.7 2 0 0 2 2 2 0 Lycopene cyclase protein Pyr_redox_3 PF13738.6 OQS00125.1 - 0.053 12.8 0.1 0.12 11.6 0.1 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 OQS00125.1 - 0.08 12.0 0.8 3.9 6.4 0.2 2.2 2 0 0 2 2 2 0 Glucose inhibited division protein A AAA PF00004.29 OQS00126.1 - 2e-42 144.8 0.1 4.8e-42 143.5 0.0 1.7 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 OQS00126.1 - 8.1e-11 41.6 0.1 2.3e-10 40.1 0.0 1.8 2 0 0 2 2 1 1 AAA+ lid domain Prot_ATP_ID_OB PF16450.5 OQS00126.1 - 5.2e-07 29.5 0.5 1.2e-06 28.4 0.5 1.6 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_5 PF07728.14 OQS00126.1 - 1e-05 25.6 0.0 5.2e-05 23.3 0.0 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 OQS00126.1 - 1.7e-05 25.0 0.1 5.6e-05 23.3 0.0 1.8 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 OQS00126.1 - 1.8e-05 25.2 0.1 0.00016 22.1 0.1 2.3 1 1 1 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 OQS00126.1 - 4.3e-05 23.8 0.7 0.011 16.0 0.0 2.8 2 1 1 3 3 3 1 AAA domain RuvB_N PF05496.12 OQS00126.1 - 0.00015 21.5 0.0 0.0003 20.6 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 OQS00126.1 - 0.0018 18.4 0.0 0.0039 17.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 OQS00126.1 - 0.0026 17.5 0.0 0.0053 16.5 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_18 PF13238.6 OQS00126.1 - 0.0036 17.9 0.1 0.022 15.3 0.0 2.4 3 0 0 3 3 2 1 AAA domain TIP49 PF06068.13 OQS00126.1 - 0.0041 16.4 0.0 0.0082 15.4 0.0 1.5 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_3 PF07726.11 OQS00126.1 - 0.0059 16.5 0.0 0.017 15.0 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 OQS00126.1 - 0.0063 16.0 0.1 0.18 11.3 0.0 2.4 2 0 0 2 2 2 1 PhoH-like protein Mg_chelatase PF01078.21 OQS00126.1 - 0.007 15.8 0.1 0.018 14.4 0.1 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_28 PF13521.6 OQS00126.1 - 0.007 16.6 0.0 0.015 15.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain Sigma54_activat PF00158.26 OQS00126.1 - 0.0084 15.8 0.1 0.059 13.1 0.1 2.3 1 1 0 1 1 1 1 Sigma-54 interaction domain TsaE PF02367.17 OQS00126.1 - 0.018 15.0 0.0 0.034 14.1 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE RILP PF11461.8 OQS00126.1 - 0.021 15.0 1.1 0.05 13.8 1.1 1.6 1 0 0 1 1 1 0 Rab interacting lysosomal protein RNA_helicase PF00910.22 OQS00126.1 - 0.023 15.1 0.0 0.045 14.1 0.0 1.5 1 0 0 1 1 1 0 RNA helicase Parvo_NS1 PF01057.17 OQS00126.1 - 0.028 13.5 0.0 0.078 12.1 0.0 1.7 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 AAA_24 PF13479.6 OQS00126.1 - 0.03 14.0 0.0 0.095 12.4 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 OQS00126.1 - 0.033 13.7 0.0 0.066 12.7 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region ATPase PF06745.13 OQS00126.1 - 0.036 13.4 0.0 0.12 11.7 0.0 1.8 2 0 0 2 2 2 0 KaiC AAA_14 PF13173.6 OQS00126.1 - 0.036 14.1 0.0 0.11 12.6 0.0 1.8 2 0 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 OQS00126.1 - 0.048 13.6 0.1 0.15 12.0 0.0 1.8 2 0 0 2 2 1 0 RsgA GTPase AAA_25 PF13481.6 OQS00126.1 - 0.058 13.0 0.0 0.16 11.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.13 OQS00126.1 - 0.066 12.4 0.0 0.13 11.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) NACHT PF05729.12 OQS00126.1 - 0.098 12.6 0.0 0.69 9.8 0.0 2.1 1 1 1 2 2 2 0 NACHT domain Zeta_toxin PF06414.12 OQS00126.1 - 0.13 11.6 0.0 0.26 10.5 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin MscS_porin PF12795.7 OQS00126.1 - 0.28 10.7 5.1 0.46 10.0 5.1 1.2 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain HR1 PF02185.16 OQS00126.1 - 0.34 11.0 7.3 1.3 9.2 7.4 1.9 1 1 0 1 1 1 0 Hr1 repeat Hexapep PF00132.24 OQS00127.1 - 2.6e-21 74.5 23.2 1.2e-06 28.0 0.3 6.4 5 1 2 7 7 7 6 Bacterial transferase hexapeptide (six repeats) Acetyltransf_11 PF13720.6 OQS00127.1 - 7.4e-14 52.0 0.2 2.1e-13 50.5 0.2 1.8 1 1 0 1 1 1 1 Udp N-acetylglucosamine O-acyltransferase; Domain 2 Bactofilin PF04519.13 OQS00127.1 - 0.1 12.9 9.3 0.17 12.2 2.7 2.8 1 1 2 3 3 3 0 Polymer-forming cytoskeletal Hexapep_2 PF14602.6 OQS00127.1 - 0.14 11.9 21.0 7.3 6.4 0.1 6.3 4 2 2 6 6 6 0 Hexapeptide repeat of succinyl-transferase Pkinase PF00069.25 OQS00128.1 - 1.7e-66 224.3 0.0 2.3e-66 223.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQS00128.1 - 2.7e-33 115.3 0.0 4.2e-33 114.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OQS00128.1 - 9.3e-05 21.9 0.0 0.00016 21.1 0.0 1.3 1 0 0 1 1 1 1 Kinase-like PH PF00169.29 OQS00128.1 - 0.0025 18.3 0.0 0.0054 17.2 0.0 1.5 1 0 0 1 1 1 1 PH domain APH PF01636.23 OQS00128.1 - 0.083 12.8 0.4 0.26 11.2 0.3 1.7 1 1 0 1 1 1 0 Phosphotransferase enzyme family Peptidase_M14 PF00246.24 OQS00129.1 - 4.5e-37 128.4 1.0 5.3e-37 128.2 1.0 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase Phi-29_GP4 PF05464.11 OQS00129.1 - 0.04 14.2 0.4 4.1 7.7 0.0 2.8 3 0 0 3 3 3 0 Phi-29-like late genes activator (early protein GP4) FYVE PF01363.21 OQS00130.1 - 9.7e-11 41.7 14.1 1.9e-10 40.7 14.1 1.5 1 0 0 1 1 1 1 FYVE zinc finger START PF01852.19 OQS00130.1 - 1.9e-10 40.5 0.0 3.5e-10 39.6 0.0 1.4 1 1 0 1 1 1 1 START domain FlhC PF05280.11 OQS00130.1 - 0.0089 15.8 2.4 0.018 14.8 2.4 1.5 1 0 0 1 1 1 1 Flagellar transcriptional activator (FlhC) UPF0515 PF15135.6 OQS00130.1 - 0.087 12.2 7.7 0.14 11.5 7.7 1.2 1 0 0 1 1 1 0 Uncharacterised protein UPF0515 zf-C2HC5 PF06221.13 OQS00130.1 - 3 7.9 8.3 15 5.7 8.3 2.2 1 1 0 1 1 1 0 Putative zinc finger motif, C2HC5-type zf-RING_5 PF14634.6 OQS00130.1 - 3.1 7.8 16.7 0.57 10.2 12.9 1.9 2 0 0 2 2 2 0 zinc-RING finger domain zf-UBP PF02148.19 OQS00130.1 - 4.4 7.7 11.3 6.3 7.2 9.9 2.1 2 0 0 2 2 2 0 Zn-finger in ubiquitin-hydrolases and other protein FYVE PF01363.21 OQS00131.1 - 0.00042 20.4 1.3 0.0011 19.1 1.3 1.6 1 0 0 1 1 1 1 FYVE zinc finger START PF01852.19 OQS00131.1 - 0.00073 19.0 0.0 0.001 18.5 0.0 1.2 1 0 0 1 1 1 1 START domain DUF3074 PF11274.8 OQS00131.1 - 0.0053 16.8 0.0 0.0095 15.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3074) ASRT PF07100.11 OQS00131.1 - 0.036 14.1 0.1 0.071 13.2 0.1 1.4 1 0 0 1 1 1 0 Anabaena sensory rhodopsin transducer START PF01852.19 OQS00132.1 - 1.5e-13 50.7 0.1 2.4e-13 50.0 0.1 1.3 1 0 0 1 1 1 1 START domain FYVE PF01363.21 OQS00132.1 - 3.2e-08 33.6 6.9 3.2e-08 33.6 6.9 2.0 2 0 0 2 2 2 1 FYVE zinc finger FYVE_2 PF02318.16 OQS00132.1 - 0.059 13.6 4.2 0.13 12.5 4.2 1.5 1 0 0 1 1 1 0 FYVE-type zinc finger Zf_RING PF16744.5 OQS00132.1 - 0.62 10.2 10.1 0.12 12.5 5.6 2.1 1 1 1 2 2 2 0 KIAA1045 RING finger DZR PF12773.7 OQS00132.1 - 4.1 7.5 7.8 25 5.0 7.8 2.4 1 1 0 1 1 1 0 Double zinc ribbon RecR PF02132.15 OQS00132.1 - 6.2 6.5 9.1 36 4.0 9.1 2.3 1 1 0 1 1 1 0 RecR protein Pkinase PF00069.25 OQS00133.1 - 7.7e-11 41.9 0.0 9.1e-11 41.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQS00133.1 - 2.2e-10 40.3 0.0 2.5e-10 40.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase LicD PF04991.13 OQS00134.1 - 2.4e-50 171.8 5.7 7e-19 68.9 0.0 5.4 3 2 0 3 3 3 3 LicD family LicD PF04991.13 OQS00135.1 - 1.8e-21 77.4 0.0 2.7e-13 50.6 0.0 2.2 1 1 0 2 2 2 2 LicD family START PF01852.19 OQS00136.1 - 1.5e-19 70.3 0.1 1.1e-09 38.0 0.0 2.3 2 0 0 2 2 2 2 START domain FYVE PF01363.21 OQS00136.1 - 1.7e-14 53.7 32.2 3.7e-07 30.2 10.4 2.5 2 0 0 2 2 2 2 FYVE zinc finger DUF3074 PF11274.8 OQS00136.1 - 0.0019 18.2 0.2 0.28 11.2 0.0 3.5 2 1 1 3 3 3 1 Protein of unknown function (DUF3074) Vps39_2 PF10367.9 OQS00136.1 - 2.3 8.7 10.5 8.9 6.8 2.5 2.8 2 0 0 2 2 2 0 Vacuolar sorting protein 39 domain 2 LicD PF04991.13 OQS00137.1 - 1.4e-15 58.1 0.3 7.4e-14 52.4 0.1 2.4 2 1 0 2 2 2 2 LicD family Syntaxin-6_N PF09177.11 OQS00139.1 - 7.5e-19 68.1 0.3 7.5e-19 68.1 0.3 2.4 2 1 0 2 2 2 1 Syntaxin 6, N-terminal SNARE PF05739.19 OQS00139.1 - 0.0024 17.9 4.2 0.0027 17.7 2.3 2.1 2 0 0 2 2 2 1 SNARE domain Act-Frag_cataly PF09192.10 OQS00139.1 - 0.0085 15.5 2.1 0.0089 15.4 1.0 1.6 1 1 1 2 2 2 1 Actin-fragmin kinase, catalytic XhlA PF10779.9 OQS00139.1 - 0.051 13.8 3.1 0.93 9.7 0.8 3.0 2 0 0 2 2 2 0 Haemolysin XhlA DUF2730 PF10805.8 OQS00139.1 - 0.16 12.1 6.6 1.5 9.0 0.0 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF2730) DUF1411 PF07199.11 OQS00139.1 - 0.19 11.4 3.8 0.21 11.2 2.9 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1411) Spc7 PF08317.11 OQS00139.1 - 0.27 10.1 9.5 0.69 8.7 3.1 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein Asparaginase PF00710.20 OQS00140.1 - 2.4e-58 196.8 0.0 3.8e-58 196.2 0.0 1.3 1 0 0 1 1 1 1 Asparaginase, N-terminal Asparaginase_C PF17763.1 OQS00140.1 - 1.2e-28 99.6 0.0 1.9e-28 98.9 0.0 1.4 1 0 0 1 1 1 1 Glutaminase/Asparaginase C-terminal domain Myb_DNA-bind_2 PF08914.11 OQS00141.1 - 1.8e-08 34.4 1.7 4.4e-08 33.2 1.7 1.7 1 0 0 1 1 1 1 Rap1 Myb domain BRCT_2 PF16589.5 OQS00141.1 - 4.3e-08 33.5 0.1 1.2e-07 32.0 0.1 1.8 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain Rap1_C PF11626.8 OQS00141.1 - 0.00077 19.5 0.0 0.0029 17.7 0.0 2.0 2 0 0 2 2 2 1 TRF2-interacting telomeric protein/Rap1 - C terminal domain DUF4286 PF14114.6 OQS00141.1 - 0.15 12.6 1.5 0.2 12.2 0.4 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4286) QLQ PF08880.11 OQS00142.1 - 0.11 12.3 0.4 0.27 11.0 0.2 1.7 2 0 0 2 2 2 0 QLQ JAB PF01398.21 OQS00143.1 - 1.7e-19 69.9 0.4 2e-18 66.5 0.0 3.0 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.6 OQS00143.1 - 2e-18 66.8 0.3 2e-18 66.8 0.3 3.5 3 2 0 3 3 3 1 Maintenance of mitochondrial structure and function UVR PF02151.19 OQS00143.1 - 4.7e-06 26.2 45.8 0.0041 16.8 2.3 5.8 6 0 0 6 6 6 4 UvrB/uvrC motif Nucleoporin_FG PF13634.6 OQS00143.1 - 2.9e-05 24.8 9.3 0.0067 17.3 1.7 3.7 3 0 0 3 3 3 2 Nucleoporin FG repeat region NADH-UOR_E PF16514.5 OQS00143.1 - 0.17 12.2 1.4 1.8 9.0 1.4 2.8 1 0 0 1 1 1 0 putative NADH-ubiquinone oxidoreductase chain E DUF4172 PF13776.6 OQS00143.1 - 0.3 11.4 3.5 1.1 9.7 0.1 3.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4172) RabGAP-TBC PF00566.18 OQS00144.1 - 2.6e-54 184.2 0.8 3.4e-54 183.7 0.8 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain PP2C PF00481.21 OQS00146.1 - 8.7e-65 218.9 0.1 9.9e-65 218.7 0.1 1.0 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 OQS00146.1 - 1.9e-06 27.7 0.0 3.9e-06 26.7 0.0 1.5 1 1 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 OQS00146.1 - 0.017 15.0 0.3 1.1 9.1 0.1 2.1 2 0 0 2 2 2 0 Stage II sporulation protein E (SpoIIE) AA_permease_2 PF13520.6 OQS00147.1 - 7.1e-29 100.9 27.8 9.5e-29 100.5 27.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 OQS00147.1 - 1.6e-15 56.7 27.1 4.7e-15 55.1 27.1 1.8 1 1 0 1 1 1 1 Amino acid permease SGL PF08450.12 OQS00148.1 - 1.3e-13 51.1 0.0 2.1e-13 50.4 0.0 1.3 1 1 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region NHL PF01436.21 OQS00148.1 - 3.6e-06 26.7 0.5 13 6.0 0.0 6.1 6 0 0 6 6 6 3 NHL repeat Arylesterase PF01731.20 OQS00148.1 - 0.00077 19.6 0.0 0.13 12.5 0.0 2.9 3 0 0 3 3 3 1 Arylesterase Methyltransf_25 PF13649.6 OQS00149.1 - 3.5e-14 53.3 0.2 1.9e-08 34.9 0.0 3.0 3 0 0 3 3 2 2 Methyltransferase domain Methyltransf_11 PF08241.12 OQS00149.1 - 2.5e-12 47.2 0.0 3.3e-08 34.1 0.0 2.7 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_31 PF13847.6 OQS00149.1 - 5.5e-10 39.2 0.1 1.6e-06 28.0 0.0 2.4 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.12 OQS00149.1 - 5.5e-07 30.3 0.1 0.038 14.7 0.0 3.1 2 1 0 2 2 2 2 Methyltransferase domain PCMT PF01135.19 OQS00149.1 - 4.1e-05 23.4 0.0 0.0003 20.6 0.1 2.2 2 0 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MTS PF05175.14 OQS00149.1 - 0.001 18.6 0.6 0.35 10.4 0.1 2.7 2 1 0 2 2 2 2 Methyltransferase small domain TPMT PF05724.11 OQS00149.1 - 0.0011 18.6 0.0 0.025 14.2 0.0 2.3 2 0 0 2 2 2 1 Thiopurine S-methyltransferase (TPMT) Spermine_synth PF01564.17 OQS00149.1 - 0.0039 16.6 0.5 0.017 14.5 0.0 2.1 2 0 0 2 2 2 1 Spermine/spermidine synthase domain DUF4159 PF13709.6 OQS00149.1 - 0.0058 16.1 0.0 0.027 13.9 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4159) MetW PF07021.12 OQS00149.1 - 0.013 15.1 0.0 0.12 11.9 0.0 2.1 2 0 0 2 2 2 0 Methionine biosynthesis protein MetW Methyltransf_4 PF02390.17 OQS00149.1 - 0.014 14.8 0.1 1 8.8 0.0 3.4 2 1 1 3 3 3 0 Putative methyltransferase RrnaAD PF00398.20 OQS00149.1 - 0.056 12.5 0.0 0.13 11.3 0.0 1.5 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase MRP-L47 PF06984.13 OQS00150.1 - 1.3e-25 89.3 0.2 1.7e-25 89.0 0.2 1.2 1 0 0 1 1 1 1 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) Ribosomal_L29 PF00831.23 OQS00150.1 - 4.3e-09 36.2 0.8 7.1e-09 35.5 0.8 1.4 1 0 0 1 1 1 1 Ribosomal L29 protein HA PF03457.14 OQS00151.1 - 6.2e-39 132.2 0.9 1.5e-11 44.4 0.2 4.2 4 1 0 4 4 4 3 Helicase associated domain SSFA2_C PF14723.6 OQS00151.1 - 0.13 12.2 0.1 0.43 10.5 0.0 1.9 2 1 1 3 3 3 0 Sperm-specific antigen 2 C-terminus Ofd1_CTDD PF10637.9 OQS00152.1 - 0.016 14.5 0.0 0.032 13.6 0.0 1.4 1 0 0 1 1 1 0 Oxoglutarate and iron-dependent oxygenase degradation C-term Rsd_AlgQ PF04353.13 OQS00152.1 - 0.054 13.4 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 Regulator of RNA polymerase sigma(70) subunit, Rsd/AlgQ Shisa PF13908.6 OQS00152.1 - 0.061 13.6 1.3 0.95 9.7 0.1 2.5 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator TPR_12 PF13424.6 OQS00153.1 - 5.2e-07 29.8 0.1 5.2e-07 29.8 0.1 2.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 OQS00153.1 - 2.4e-05 24.1 0.1 0.048 13.8 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 OQS00153.1 - 0.00043 20.0 0.0 0.051 13.4 0.0 3.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_10 PF13374.6 OQS00153.1 - 0.0097 15.8 0.5 0.048 13.5 0.0 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 OQS00153.1 - 0.018 15.7 0.0 0.14 12.8 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.6 OQS00153.1 - 0.031 14.5 0.0 2.4 8.6 0.0 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat Sulfotransfer_4 PF17784.1 OQS00153.1 - 0.054 13.3 0.6 18 5.1 0.0 2.9 2 1 0 2 2 2 0 Sulfotransferase domain Strumpellin PF10266.9 OQS00154.1 - 0 1391.6 0.8 0 1391.4 0.8 1.0 1 0 0 1 1 1 1 Hereditary spastic paraplegia protein strumpellin HSF_DNA-bind PF00447.17 OQS00155.1 - 8.7e-58 193.0 10.3 5.7e-30 103.8 2.0 2.5 3 0 0 3 3 2 2 HSF-type DNA-binding DUF4618 PF15397.6 OQS00155.1 - 0.00093 18.7 3.0 0.42 10.0 0.3 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF4618) TSC22 PF01166.18 OQS00155.1 - 0.0011 19.3 1.2 1.1 9.7 0.1 2.7 2 0 0 2 2 2 2 TSC-22/dip/bun family NPV_P10 PF05531.12 OQS00155.1 - 0.0021 18.5 2.0 0.37 11.3 0.4 2.3 2 0 0 2 2 2 1 Nucleopolyhedrovirus P10 protein DUF2205 PF10224.9 OQS00155.1 - 0.0036 17.3 2.0 1.8 8.6 0.5 2.4 2 0 0 2 2 2 2 Short coiled-coil protein Seryl_tRNA_N PF02403.22 OQS00155.1 - 0.0041 17.3 0.2 1.4 9.2 0.0 2.4 2 0 0 2 2 2 1 Seryl-tRNA synthetase N-terminal domain DUF4988 PF16378.5 OQS00155.1 - 0.0061 16.3 2.1 1.9 8.1 0.1 2.5 3 0 0 3 3 2 2 Domain of unknown function Spc7 PF08317.11 OQS00155.1 - 0.021 13.7 2.3 2 7.2 0.2 2.1 2 0 0 2 2 2 0 Spc7 kinetochore protein SlyX PF04102.12 OQS00155.1 - 0.026 15.1 2.0 1.1 9.9 0.1 2.4 2 0 0 2 2 2 0 SlyX Prefoldin PF02996.17 OQS00155.1 - 0.03 14.2 3.6 1.3 9.0 0.3 2.3 2 0 0 2 2 2 0 Prefoldin subunit DUF5320 PF17253.2 OQS00155.1 - 0.031 15.3 1.2 12 7.1 0.0 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5320) MAD PF05557.13 OQS00155.1 - 0.033 12.5 3.4 0.14 10.5 0.2 2.0 2 0 0 2 2 2 0 Mitotic checkpoint protein Bacillus_HBL PF05791.11 OQS00155.1 - 0.041 13.7 1.8 6.9 6.5 0.1 2.3 2 0 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) Lipoprotein_20 PF13942.6 OQS00155.1 - 0.045 13.7 1.9 0.67 9.8 0.4 2.2 2 0 0 2 2 2 0 YfhG lipoprotein DUF2968 PF11180.8 OQS00155.1 - 0.047 13.3 2.2 1.2 8.7 1.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2968) ACCA PF03255.14 OQS00155.1 - 0.057 13.3 1.0 0.1 12.4 0.1 1.9 2 0 0 2 2 2 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit DUF4972 PF16342.5 OQS00155.1 - 0.063 13.0 0.6 2.2 8.0 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4972) COG5 PF10392.9 OQS00155.1 - 0.066 13.4 0.7 3.2 7.9 0.0 2.4 2 0 0 2 2 2 0 Golgi transport complex subunit 5 FliD_N PF02465.18 OQS00155.1 - 0.086 13.5 0.7 9.3 7.0 0.0 2.4 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus FlxA PF14282.6 OQS00155.1 - 0.086 12.8 4.1 2.1 8.4 0.6 2.4 2 0 0 2 2 2 0 FlxA-like protein FlaC_arch PF05377.11 OQS00155.1 - 0.15 12.5 4.5 2.8 8.4 0.2 2.3 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) DUF2730 PF10805.8 OQS00155.1 - 0.15 12.1 1.5 5.4 7.2 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2730) bZIP_1 PF00170.21 OQS00155.1 - 0.18 11.9 1.3 3.2 7.9 0.1 2.3 2 0 0 2 2 2 0 bZIP transcription factor BLOC1_2 PF10046.9 OQS00155.1 - 0.23 11.8 3.5 1.8 8.9 0.5 2.4 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 CENP-F_leu_zip PF10473.9 OQS00155.1 - 0.24 11.4 3.9 6.2 6.8 0.5 2.2 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 LPP PF04728.13 OQS00155.1 - 0.51 10.8 2.7 16 5.9 0.1 2.7 2 0 0 2 2 2 0 Lipoprotein leucine-zipper DASH_Hsk3 PF08227.11 OQS00155.1 - 0.65 10.4 3.2 1.7 9.1 0.3 2.4 2 0 0 2 2 2 0 DASH complex subunit Hsk3 like Peptidase_C48 PF02902.19 OQS00156.1 - 1.5e-22 80.5 0.1 3.9e-22 79.1 0.1 1.7 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain HSF_DNA-bind PF00447.17 OQS00157.1 - 7.5e-28 97.0 2.3 1.2e-27 96.3 2.3 1.3 1 0 0 1 1 1 1 HSF-type DNA-binding DUF4140 PF13600.6 OQS00157.1 - 0.081 13.4 0.1 0.14 12.6 0.1 1.3 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) Pox_A_type_inc PF04508.12 OQS00157.1 - 0.16 11.9 0.0 0.31 10.9 0.0 1.4 1 0 0 1 1 1 0 Viral A-type inclusion protein repeat SNF2_N PF00176.23 OQS00158.1 - 1.6e-44 152.0 0.4 5.6e-44 150.3 0.4 1.7 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 OQS00158.1 - 3.6e-19 69.2 0.0 6.4e-18 65.1 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain HDA2-3 PF11496.8 OQS00158.1 - 1.3e-06 27.8 1.1 8.9e-06 25.1 0.1 2.6 2 0 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 ERCC3_RAD25_C PF16203.5 OQS00158.1 - 0.00073 18.8 0.1 0.0016 17.7 0.1 1.5 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase PBECR1 PF18809.1 OQS00158.1 - 0.03 15.0 0.1 0.14 12.9 0.1 2.1 1 0 0 1 1 1 0 phage-Barnase-EndoU-ColicinE5/D-RelE like nuclease1 Ras PF00071.22 OQS00159.1 - 9.1e-59 197.7 0.0 1e-58 197.5 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OQS00159.1 - 5.6e-34 116.9 0.0 8.5e-34 116.4 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OQS00159.1 - 4.2e-15 55.6 0.0 5.7e-15 55.2 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 OQS00159.1 - 0.0025 17.9 0.0 0.004 17.2 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 OQS00159.1 - 0.006 16.1 0.1 0.027 14.0 0.1 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 OQS00159.1 - 0.014 14.8 0.0 0.017 14.5 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 OQS00159.1 - 0.073 13.0 0.0 11 5.8 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase TniB PF05621.11 OQS00159.1 - 0.15 11.5 0.1 0.64 9.4 0.0 1.8 2 0 0 2 2 2 0 Bacterial TniB protein ORMDL PF04061.14 OQS00160.1 - 5.6e-42 142.8 0.7 6.4e-42 142.6 0.7 1.0 1 0 0 1 1 1 1 ORMDL family STIL_N PF15253.6 OQS00161.1 - 1.7e-11 43.7 7.0 1.3e-10 40.9 6.3 2.3 2 1 0 2 2 2 1 SCL-interrupting locus protein N-terminus DUF3573 PF12097.8 OQS00161.1 - 0.071 11.9 0.1 0.097 11.5 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) FlxA PF14282.6 OQS00161.1 - 0.16 12.0 8.1 0.3 11.1 8.1 1.4 1 0 0 1 1 1 0 FlxA-like protein TolA_bind_tri PF16331.5 OQS00161.1 - 0.84 9.8 10.9 0.61 10.2 8.8 1.8 2 0 0 2 2 2 0 TolA binding protein trimerisation Mago_nashi PF02792.14 OQS00162.1 - 5.1e-71 237.4 1.4 5.7e-71 237.2 1.4 1.0 1 0 0 1 1 1 1 Mago nashi protein Mito_carr PF00153.27 OQS00163.1 - 4.7e-43 145.0 2.3 2.8e-18 65.6 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 OQS00163.1 - 0.025 13.7 0.9 0.033 13.3 0.1 1.6 2 0 0 2 2 2 0 Gammaproteobacterial serine protease HA PF03457.14 OQS00164.1 - 2.8e-08 34.0 0.2 8.9e-08 32.4 0.1 1.9 2 0 0 2 2 2 1 Helicase associated domain RNA_pol_L_2 PF13656.6 OQS00166.1 - 1e-29 102.1 0.1 1.3e-29 101.8 0.1 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.24 OQS00166.1 - 2e-10 39.9 0.0 3.4e-10 39.2 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Nup54 PF13874.6 OQS00166.1 - 0.13 12.4 2.4 0.19 11.8 2.3 1.3 1 1 0 1 1 1 0 Nucleoporin complex subunit 54 DUF1970 PF09301.10 OQS00166.1 - 0.16 12.3 0.0 0.2 12.0 0.0 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF1970) AA_kinase PF00696.28 OQS00167.1 - 6e-39 134.1 2.0 1.5e-38 132.8 0.8 2.1 2 1 0 2 2 2 1 Amino acid kinase family Homoserine_dh PF00742.19 OQS00167.1 - 2.6e-15 56.8 0.0 5.8e-15 55.6 0.0 1.7 1 0 0 1 1 1 1 Homoserine dehydrogenase ACT PF01842.25 OQS00167.1 - 1.1e-14 53.9 0.6 3.2e-06 26.8 0.0 2.8 2 0 0 2 2 2 2 ACT domain ACT_7 PF13840.6 OQS00167.1 - 9.3e-13 47.8 0.1 3.8e-06 26.6 0.0 3.1 2 0 0 2 2 2 2 ACT domain ACT_6 PF13740.6 OQS00167.1 - 0.0026 17.7 2.2 0.7 9.9 0.0 3.6 4 0 0 4 4 4 2 ACT domain FYVE PF01363.21 OQS00168.1 - 1.4e-15 57.2 9.4 1.4e-15 57.2 9.4 2.6 2 1 0 2 2 1 1 FYVE zinc finger zf-RING_2 PF13639.6 OQS00168.1 - 2.1e-13 50.4 28.1 5.8e-13 49.0 9.4 2.8 3 0 0 3 3 2 2 Ring finger domain zf-C3HC4_2 PF13923.6 OQS00168.1 - 4.9e-09 35.9 8.9 4.9e-09 35.9 8.9 3.9 4 1 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 OQS00168.1 - 3.8e-08 32.9 6.4 3.8e-08 32.9 6.4 2.7 3 0 0 3 3 3 1 RING-like zinc finger zf-RING_UBOX PF13445.6 OQS00168.1 - 3e-07 30.3 4.1 3e-07 30.3 4.1 3.1 3 2 1 4 4 4 1 RING-type zinc-finger zf-C3HC4 PF00097.25 OQS00168.1 - 6.4e-06 25.9 7.5 6.4e-06 25.9 7.5 3.2 3 1 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OQS00168.1 - 6.9e-06 25.9 5.6 6.9e-06 25.9 5.6 3.1 3 1 1 4 4 4 1 zinc-RING finger domain zf-rbx1 PF12678.7 OQS00168.1 - 7.2e-06 26.2 12.4 7.2e-06 26.2 12.4 3.7 2 2 1 3 3 2 1 RING-H2 zinc finger domain Prok-RING_4 PF14447.6 OQS00168.1 - 1.1e-05 25.2 20.0 3.8e-05 23.4 5.5 2.7 2 0 0 2 2 2 2 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 OQS00168.1 - 8.2e-05 22.4 4.5 8.2e-05 22.4 4.5 3.1 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 OQS00168.1 - 0.0013 18.7 6.5 0.0013 18.7 6.5 2.8 2 2 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_ribbon_17 PF17120.5 OQS00168.1 - 0.024 14.2 8.8 0.024 14.2 8.8 3.6 2 1 1 3 3 3 0 Zinc-ribbon, C4HC2 type zf-RING_4 PF14570.6 OQS00168.1 - 0.035 13.9 3.2 0.035 13.9 3.2 3.3 3 0 0 3 3 3 0 RING/Ubox like zinc-binding domain zf_C2HC_14 PF18574.1 OQS00168.1 - 1.9 8.3 9.1 0.49 10.2 3.7 2.6 2 0 0 2 2 2 0 C2HC Zing finger domain zf_C2H2_10 PF18414.1 OQS00168.1 - 5 6.8 8.3 2.4 7.8 0.3 3.3 3 0 0 3 3 3 0 C2H2 type zinc-finger Rad50_zn_hook PF04423.14 OQS00168.1 - 5.2 7.0 5.5 3.1 7.7 0.2 2.9 3 0 0 3 3 3 0 Rad50 zinc hook motif CHCH PF06747.13 OQS00169.1 - 3.6e-05 23.8 5.0 4.8e-05 23.4 5.0 1.2 1 0 0 1 1 1 1 CHCH domain Cmc1 PF08583.10 OQS00169.1 - 0.0011 18.9 6.2 0.044 13.8 0.7 2.1 1 1 1 2 2 2 2 Cytochrome c oxidase biogenesis protein Cmc1 like NDUF_B7 PF05676.13 OQS00169.1 - 0.0083 15.8 1.5 0.011 15.5 1.5 1.2 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) Pet191_N PF10203.9 OQS00169.1 - 0.014 15.7 2.7 0.019 15.3 2.7 1.1 1 0 0 1 1 1 0 Cytochrome c oxidase assembly protein PET191 COX17 PF05051.13 OQS00169.1 - 0.13 12.6 3.1 0.18 12.2 3.1 1.2 1 0 0 1 1 1 0 Cytochrome C oxidase copper chaperone (COX17) UPF0203 PF05254.12 OQS00169.1 - 0.27 11.5 5.6 0.69 10.2 5.6 1.6 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0203) cNMP_binding PF00027.29 OQS00170.1 - 1.2e-39 134.2 6.3 5.1e-08 32.9 0.0 10.3 8 4 0 8 8 8 6 Cyclic nucleotide-binding domain TPR_12 PF13424.6 OQS00171.1 - 6.6e-14 52.0 8.0 2.2e-08 34.3 4.4 4.2 2 1 2 4 4 4 3 Tetratricopeptide repeat TPR_10 PF13374.6 OQS00171.1 - 1.4e-09 37.5 7.3 0.00032 20.5 1.1 5.1 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_1 PF00515.28 OQS00171.1 - 2.8e-09 36.4 6.5 0.25 11.3 0.3 5.4 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_2 PF07719.17 OQS00171.1 - 2.7e-08 33.3 6.6 0.026 14.6 0.3 5.0 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_8 PF13181.6 OQS00171.1 - 1e-05 25.3 5.8 0.34 11.2 0.1 5.1 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_7 PF13176.6 OQS00171.1 - 7.6e-05 22.5 3.8 0.016 15.2 0.1 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.6 OQS00171.1 - 0.0065 17.1 1.2 0.038 14.6 0.5 2.3 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.6 OQS00171.1 - 0.0065 16.9 3.7 0.02 15.4 0.9 2.9 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_MalT PF17874.1 OQS00171.1 - 0.0081 15.6 6.2 0.0081 15.6 4.3 1.5 1 1 0 1 1 1 1 MalT-like TPR region TPR_11 PF13414.6 OQS00171.1 - 0.011 15.4 1.5 0.16 11.7 0.0 3.4 3 1 0 3 3 3 0 TPR repeat TPR_14 PF13428.6 OQS00171.1 - 0.094 13.6 3.9 49 5.1 0.0 3.8 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_15 PF13429.6 OQS00171.1 - 0.4 9.8 3.5 0.46 9.6 0.2 2.3 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_17 PF13431.6 OQS00171.1 - 0.79 10.2 3.7 5.3 7.7 0.1 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat Dus PF01207.17 OQS00172.1 - 4.7e-62 209.9 0.0 5.5e-62 209.6 0.0 1.1 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) ANP PF00212.18 OQS00172.1 - 0.2 11.9 0.3 0.44 10.8 0.3 1.5 1 0 0 1 1 1 0 Atrial natriuretic peptide His_biosynth PF00977.21 OQS00172.1 - 0.2 11.1 0.0 0.44 10.0 0.0 1.5 1 0 0 1 1 1 0 Histidine biosynthesis protein DUF4787 PF16029.5 OQS00173.1 - 5.8e-17 61.5 7.0 7.3e-17 61.2 7.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4787) DIOX_N PF14226.6 OQS00174.1 - 3.4e-23 82.6 0.0 1.7e-22 80.4 0.0 2.0 2 0 0 2 2 2 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 OQS00174.1 - 2.3e-20 73.0 0.1 3.8e-20 72.3 0.1 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily RuBisCO_small PF00101.20 OQS00174.1 - 0.15 12.1 0.0 0.29 11.1 0.0 1.4 1 0 0 1 1 1 0 Ribulose bisphosphate carboxylase, small chain Pkr1 PF08636.10 OQS00175.1 - 1.6e-10 41.0 4.4 1.8e-10 40.8 4.4 1.1 1 0 0 1 1 1 1 ER protein Pkr1 DUF983 PF06170.12 OQS00175.1 - 0.021 15.2 1.3 0.026 14.9 1.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF983) Arf PF00025.21 OQS00176.1 - 2e-24 86.0 0.0 1.4e-19 70.2 0.0 2.0 2 0 0 2 2 2 2 ADP-ribosylation factor family Ras PF00071.22 OQS00176.1 - 9.7e-05 22.0 0.1 0.0031 17.1 0.0 2.1 2 0 0 2 2 2 1 Ras family NACHT PF05729.12 OQS00176.1 - 0.00041 20.3 0.1 0.00097 19.1 0.1 1.7 1 1 1 2 2 2 1 NACHT domain GTP_EFTU PF00009.27 OQS00176.1 - 0.00068 19.2 0.1 0.055 13.0 0.1 2.3 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain cobW PF02492.19 OQS00176.1 - 0.0018 17.9 0.0 0.33 10.5 0.0 2.2 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain Roc PF08477.13 OQS00176.1 - 0.0028 17.9 0.1 1.5 9.0 0.0 2.3 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase AAA_16 PF13191.6 OQS00176.1 - 0.0047 17.3 0.0 0.015 15.7 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 OQS00176.1 - 0.0084 16.4 0.0 0.02 15.2 0.0 1.7 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 OQS00176.1 - 0.016 15.1 0.0 1.3 8.9 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase SRPRB PF09439.10 OQS00176.1 - 0.027 13.9 0.0 2.3 7.6 0.0 2.2 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit AAA_33 PF13671.6 OQS00176.1 - 0.041 14.0 0.0 0.084 13.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain SRP54 PF00448.22 OQS00176.1 - 0.068 12.8 0.0 0.18 11.4 0.0 1.7 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain ABC_tran PF00005.27 OQS00176.1 - 0.07 13.6 0.0 0.099 13.2 0.0 1.4 1 0 0 1 1 1 0 ABC transporter AAA_30 PF13604.6 OQS00176.1 - 0.13 12.0 0.0 0.23 11.2 0.0 1.5 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 OQS00176.1 - 0.2 12.2 0.0 0.3 11.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain NUDIX PF00293.28 OQS00178.1 - 1.3e-10 41.4 0.0 1.7e-10 41.0 0.0 1.1 1 0 0 1 1 1 1 NUDIX domain Fimbrial_K88 PF02432.15 OQS00178.1 - 0.091 12.7 0.0 0.14 12.1 0.0 1.3 1 0 0 1 1 1 0 Fimbrial, major and minor subunit PS_Dcarbxylase PF02666.15 OQS00179.1 - 1.1e-58 198.1 0.0 1.4e-58 197.7 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase Ribosomal_L27 PF01016.19 OQS00180.1 - 2e-36 123.8 1.0 2e-36 123.8 1.0 1.4 1 1 0 1 1 1 1 Ribosomal L27 protein HIT PF01230.23 OQS00181.1 - 5.6e-26 91.1 0.0 8.1e-26 90.6 0.0 1.2 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 OQS00181.1 - 3.1e-08 34.1 0.0 4.4e-08 33.6 0.0 1.2 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding Pkinase PF00069.25 OQS00183.1 - 1.9e-44 152.0 0.0 2.6e-44 151.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQS00183.1 - 1.5e-43 148.9 0.0 2e-43 148.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 OQS00183.1 - 7.2e-05 22.8 0.0 0.017 15.1 0.0 2.3 2 0 0 2 2 2 2 Phosphotransferase enzyme family Haspin_kinase PF12330.8 OQS00183.1 - 0.041 12.8 0.1 0.077 11.9 0.0 1.4 2 0 0 2 2 2 0 Haspin like kinase domain Pkinase_fungal PF17667.1 OQS00183.1 - 0.18 10.5 0.0 0.26 10.0 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase DUF2744 PF10910.8 OQS00185.1 - 0.065 13.2 0.0 0.11 12.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2744) hNIFK_binding PF12196.8 OQS00185.1 - 0.1 12.1 0.8 10 5.7 0.1 2.6 2 0 0 2 2 2 0 FHA Ki67 binding domain of hNIFK ABC_tran PF00005.27 OQS00186.1 - 5.3e-15 56.1 0.0 6.9e-15 55.8 0.0 1.2 1 0 0 1 1 1 1 ABC transporter RsgA_GTPase PF03193.16 OQS00186.1 - 9.3e-06 25.6 0.0 1.2e-05 25.3 0.0 1.2 1 0 0 1 1 1 1 RsgA GTPase AAA_29 PF13555.6 OQS00186.1 - 0.00037 20.2 0.1 0.00071 19.3 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_21 PF13304.6 OQS00186.1 - 0.00072 19.5 0.0 0.00088 19.2 0.0 1.2 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 OQS00186.1 - 0.00074 19.9 0.0 0.00086 19.7 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain MMR_HSR1 PF01926.23 OQS00186.1 - 0.0028 17.7 0.1 0.027 14.5 0.0 2.1 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_23 PF13476.6 OQS00186.1 - 0.0034 17.9 0.0 0.0087 16.6 0.0 1.7 1 1 0 1 1 1 1 AAA domain Rad17 PF03215.15 OQS00186.1 - 0.0053 16.7 0.0 0.0068 16.3 0.0 1.2 1 0 0 1 1 1 1 Rad17 P-loop domain ATPase_2 PF01637.18 OQS00186.1 - 0.0092 15.9 0.0 0.012 15.5 0.0 1.3 1 1 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_30 PF13604.6 OQS00186.1 - 0.034 13.9 0.0 0.044 13.5 0.0 1.2 1 0 0 1 1 1 0 AAA domain cobW PF02492.19 OQS00186.1 - 0.035 13.7 0.1 0.25 10.9 0.0 2.0 1 1 1 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain SMC_N PF02463.19 OQS00186.1 - 0.051 13.0 0.1 0.07 12.5 0.1 1.4 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain AAA_18 PF13238.6 OQS00186.1 - 0.074 13.6 0.0 0.098 13.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 OQS00186.1 - 0.082 13.3 0.1 0.14 12.6 0.1 1.4 1 0 0 1 1 1 0 RNA helicase DUF4515 PF14988.6 OQS00187.1 - 0.00016 21.6 30.9 0.00016 21.6 30.9 3.0 2 1 1 3 3 3 2 Domain of unknown function (DUF4515) PRMT5_C PF17286.2 OQS00187.1 - 0.037 13.9 0.0 0.072 13.0 0.0 1.4 1 0 0 1 1 1 0 PRMT5 oligomerisation domain Nucleopor_Nup85 PF07575.13 OQS00190.1 - 1.6e-42 145.9 5.0 2.4e-42 145.3 5.0 1.2 1 0 0 1 1 1 1 Nup85 Nucleoporin zf-C2H2 PF00096.26 OQS00191.1 - 2e-22 78.4 21.6 3e-06 27.4 0.2 4.7 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 OQS00191.1 - 6.4e-21 73.8 24.6 1.9e-09 37.5 0.2 6.0 6 0 0 6 6 6 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 OQS00191.1 - 1.2e-16 59.9 20.0 0.00041 21.0 0.2 5.0 4 0 0 4 4 4 4 C2H2-type zinc finger zf-met PF12874.7 OQS00191.1 - 9.4e-09 35.4 8.2 0.031 14.7 0.0 4.4 4 0 0 4 4 4 3 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 OQS00191.1 - 2.9e-08 33.8 5.6 0.00089 19.5 0.1 3.9 4 0 0 4 4 3 2 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 OQS00191.1 - 1.9e-06 27.7 8.7 0.0022 17.9 0.1 4.4 4 0 0 4 4 4 2 C2H2-type zinc finger zf_UBZ PF18439.1 OQS00191.1 - 0.00065 19.2 6.4 0.25 11.0 0.3 3.8 3 0 0 3 3 3 2 Ubiquitin-Binding Zinc Finger C1_4 PF07975.12 OQS00191.1 - 0.001 19.3 9.3 0.31 11.3 0.7 4.0 1 1 3 4 4 4 3 TFIIH C1-like domain Zn_ribbon_SprT PF17283.2 OQS00191.1 - 0.001 18.9 4.5 1.6 8.7 0.8 4.1 3 0 0 3 3 3 1 SprT-like zinc ribbon domain zf-H2C2_5 PF13909.6 OQS00191.1 - 0.0016 18.1 21.4 0.16 11.7 0.5 4.7 5 1 0 5 5 4 3 C2H2-type zinc-finger domain zf-trcl PF13451.6 OQS00191.1 - 0.0069 16.3 4.1 0.031 14.2 0.8 2.6 2 0 0 2 2 2 1 Probable zinc-ribbon domain zinc_ribbon_9 PF14369.6 OQS00191.1 - 0.012 15.8 2.3 0.25 11.7 0.1 3.3 3 0 0 3 3 3 0 zinc-ribbon zf-DNA_Pol PF08996.10 OQS00191.1 - 0.037 13.8 6.0 0.52 10.0 0.4 2.3 1 1 1 2 2 2 0 DNA Polymerase alpha zinc finger zf_C2HC_14 PF18574.1 OQS00191.1 - 0.05 13.4 6.3 0.078 12.8 0.0 3.2 3 0 0 3 3 3 0 C2HC Zing finger domain zf-MYST PF17772.1 OQS00191.1 - 0.058 13.0 2.2 0.34 10.5 0.1 2.7 3 0 0 3 3 3 0 MYST family zinc finger domain Zn-C2H2_12 PF18112.1 OQS00191.1 - 0.17 12.4 6.2 2.8 8.5 0.4 3.5 3 0 0 3 3 3 0 Autophagy receptor zinc finger-C2H2 domain zf-LYAR PF08790.11 OQS00191.1 - 0.19 11.7 6.5 1.5 8.8 0.1 4.1 5 0 0 5 5 5 0 LYAR-type C2HC zinc finger DUF3268 PF11672.8 OQS00191.1 - 0.24 11.7 8.6 0.38 11.1 1.1 2.9 3 0 0 3 3 3 0 zinc-finger-containing domain Zn-ribbon_8 PF09723.10 OQS00191.1 - 0.39 10.9 14.8 1.1 9.4 2.4 4.1 4 1 2 6 6 5 0 Zinc ribbon domain zf_C2H2_ZHX PF18387.1 OQS00191.1 - 0.41 10.3 3.8 0.5 10.0 0.2 2.7 1 1 2 3 3 3 0 Zinc-fingers and homeoboxes C2H2 finger domain Mut7-C PF01927.16 OQS00191.1 - 0.76 9.9 4.9 6.6 6.8 0.3 2.5 1 1 1 2 2 2 0 Mut7-C RNAse domain DUF629 PF04780.12 OQS00191.1 - 0.9 8.0 5.9 0.33 9.4 1.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF629) CpXC PF14353.6 OQS00191.1 - 1 9.5 7.5 18 5.4 0.1 3.2 1 1 0 2 2 2 0 CpXC protein A2L_zn_ribbon PF08792.10 OQS00191.1 - 1.2 9.0 0.0 1.2 9.0 0.0 3.8 4 0 0 4 4 4 0 A2L zinc ribbon domain zinc-ribbons_6 PF07191.12 OQS00191.1 - 3.2 7.8 11.4 51 3.9 8.2 3.6 2 1 0 2 2 2 0 zinc-ribbons zf-AN1 PF01428.16 OQS00191.1 - 4.9 7.4 11.0 24 5.2 0.2 4.4 4 0 0 4 4 4 0 AN1-like Zinc finger zinc_ribbon_4 PF13717.6 OQS00191.1 - 5.2 7.1 9.0 9.1 6.3 0.2 3.7 4 0 0 4 4 4 0 zinc-ribbon domain CorA PF01544.18 OQS00192.1 - 8.4e-40 136.9 1.6 9.7e-34 117.0 0.4 2.2 2 0 0 2 2 2 2 CorA-like Mg2+ transporter protein EF-hand_6 PF13405.6 OQS00192.1 - 9.6e-07 28.3 1.7 0.00017 21.3 0.4 3.3 3 0 0 3 3 3 1 EF-hand domain EF-hand_1 PF00036.32 OQS00192.1 - 1.4e-06 27.5 1.2 5e-06 25.7 0.7 2.4 3 0 0 3 3 3 1 EF hand EF-hand_8 PF13833.6 OQS00192.1 - 3.9e-06 26.6 0.1 1.1e-05 25.2 0.1 1.8 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_7 PF13499.6 OQS00192.1 - 6.8e-06 26.4 0.5 3.4e-05 24.2 0.1 2.5 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_5 PF13202.6 OQS00192.1 - 7.6e-06 25.2 0.1 2.8e-05 23.4 0.1 2.0 2 0 0 2 2 2 1 EF hand DUF2207 PF09972.9 OQS00192.1 - 0.00014 20.8 0.1 0.00021 20.2 0.1 1.2 1 0 0 1 1 1 1 Predicted membrane protein (DUF2207) DUF4890 PF16231.5 OQS00192.1 - 0.013 16.0 0.1 0.032 14.7 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4890) DUF148 PF02520.17 OQS00192.1 - 0.065 13.3 0.7 0.18 12.0 0.2 1.9 2 0 0 2 2 2 0 Domain of unknown function DUF148 Ricin_B_lectin PF00652.22 OQS00194.1 - 0.014 15.6 0.0 0.02 15.1 0.0 1.2 1 0 0 1 1 1 0 Ricin-type beta-trefoil lectin domain MIX PF18529.1 OQS00194.1 - 0.15 11.8 0.2 2.6 7.7 0.0 1.9 1 1 1 2 2 2 0 Mitochondrial membrane-anchored proteins Mito_carr PF00153.27 OQS00195.1 - 2e-56 187.9 6.2 2e-19 69.3 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 OQS00195.1 - 0.21 10.7 1.8 5.3 6.1 0.0 2.9 3 1 0 3 3 3 0 Gammaproteobacterial serine protease WD40 PF00400.32 OQS00196.1 - 0.00049 20.9 0.5 0.028 15.3 0.5 3.0 1 1 0 1 1 1 1 WD domain, G-beta repeat GreA_GreB PF01272.19 OQS00196.1 - 0.11 12.4 0.1 0.34 10.9 0.0 1.8 2 0 0 2 2 2 0 Transcription elongation factor, GreA/GreB, C-term ANAPC4_WD40 PF12894.7 OQS00196.1 - 0.13 12.5 0.1 15 6.0 0.0 2.9 2 1 1 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain SWIM PF04434.17 OQS00197.1 - 6.1e-10 38.6 0.6 1.2e-09 37.6 0.6 1.5 1 0 0 1 1 1 1 SWIM zinc finger MULE PF10551.9 OQS00197.1 - 2.5e-08 34.2 0.0 8.4e-08 32.5 0.0 1.9 1 0 0 1 1 1 1 MULE transposase domain DBD_Tnp_Mut PF03108.15 OQS00197.1 - 0.00013 21.9 0.4 0.00025 20.9 0.4 1.4 1 0 0 1 1 1 1 MuDR family transposase Transposase_mut PF00872.18 OQS00197.1 - 0.036 12.9 0.0 0.061 12.2 0.0 1.3 1 0 0 1 1 1 0 Transposase, Mutator family Phage_attach PF05354.11 OQS00198.1 - 3.1e-05 23.8 0.9 10 6.0 0.0 6.2 6 2 2 8 8 8 2 Phage Head-Tail Attachment MS_channel PF00924.18 OQS00198.1 - 0.015 14.8 1.6 0.5 9.9 0.0 2.9 3 0 0 3 3 3 0 Mechanosensitive ion channel PTSIIA_gutA PF03829.13 OQS00198.1 - 0.041 13.8 2.8 25 4.8 0.0 5.5 6 0 0 6 6 6 0 PTS system glucitol/sorbitol-specific IIA component IBN_N PF03810.19 OQS00200.1 - 7.1e-16 57.9 0.5 1.7e-12 47.0 0.0 4.2 4 0 0 4 4 4 1 Importin-beta N-terminal domain Cse1 PF08506.10 OQS00200.1 - 4.1e-09 35.7 2.2 0.0016 17.3 0.0 2.9 3 0 0 3 3 3 2 Cse1 Xpo1 PF08389.12 OQS00200.1 - 8.5e-08 32.4 1.5 7.3e-07 29.4 0.2 3.3 3 0 0 3 3 3 1 Exportin 1-like protein TetR_C_32 PF09209.11 OQS00200.1 - 0.068 13.2 0.0 0.35 10.8 0.0 2.3 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain MCM PF00493.23 OQS00201.1 - 7.6e-98 326.1 0.0 2.6e-97 324.3 0.0 1.9 2 0 0 2 2 2 1 MCM P-loop domain MCM_OB PF17207.3 OQS00201.1 - 1.2e-29 102.7 1.0 2.3e-29 101.8 1.0 1.5 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 OQS00201.1 - 5.5e-22 78.0 0.4 1.2e-21 76.9 0.4 1.6 1 0 0 1 1 1 1 MCM AAA-lid domain Mg_chelatase PF01078.21 OQS00201.1 - 5e-08 32.6 0.8 1.4e-05 24.6 0.0 3.1 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI MCM_N PF14551.6 OQS00201.1 - 1.8e-05 25.2 0.1 0.00011 22.7 0.1 2.3 2 0 0 2 2 2 1 MCM N-terminal domain TPR_20 PF14561.6 OQS00201.1 - 0.01 16.2 0.2 0.039 14.3 0.2 2.0 1 0 0 1 1 1 0 Tetratricopeptide repeat AAA_3 PF07726.11 OQS00201.1 - 0.015 15.1 0.1 0.056 13.3 0.0 2.0 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Arginase PF00491.21 OQS00202.1 - 6.7e-18 65.2 0.0 8.3e-18 64.9 0.0 1.1 1 0 0 1 1 1 1 Arginase family PspB PF06667.12 OQS00202.1 - 0.036 14.1 0.4 0.074 13.1 0.0 1.7 2 0 0 2 2 2 0 Phage shock protein B DUF5610 PF18433.1 OQS00202.1 - 0.12 12.9 1.0 13 6.4 0.2 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF5610) Orai-1 PF07856.12 OQS00203.1 - 4.4e-08 33.0 1.3 8.5e-08 32.1 1.3 1.4 1 0 0 1 1 1 1 Mediator of CRAC channel activity PGM_PMM_I PF02878.16 OQS00204.1 - 3.6e-32 111.0 0.0 7.9e-32 109.8 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.16 OQS00204.1 - 5.1e-21 75.2 0.0 1.4e-20 73.9 0.0 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_III PF02880.16 OQS00204.1 - 3e-16 59.6 0.2 6e-16 58.7 0.2 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_IV PF00408.20 OQS00204.1 - 4.4e-08 33.2 0.0 1.6e-07 31.4 0.0 2.0 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain RNase_PH PF01138.21 OQS00205.1 - 4.9e-36 124.1 0.1 6.4e-36 123.8 0.1 1.1 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 OQS00205.1 - 8e-07 29.0 0.1 1.7e-06 28.0 0.1 1.6 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 Exo_endo_phos PF03372.23 OQS00206.1 - 1.4e-06 28.0 0.0 2.4e-06 27.2 0.0 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Leader_Trp PF08255.11 OQS00206.1 - 0.59 10.2 3.1 2 8.6 0.8 2.7 2 0 0 2 2 2 0 Trp-operon Leader Peptide TCR PF03638.15 OQS00207.1 - 2.8e-17 62.7 56.0 6.3e-10 39.2 26.4 2.3 2 0 0 2 2 2 2 Tesmin/TSO1-like CXC domain, cysteine-rich domain Porin_3 PF01459.22 OQS00208.1 - 3.8e-12 46.2 0.0 6.9e-12 45.4 0.0 1.4 1 0 0 1 1 1 1 Eukaryotic porin DEAD PF00270.29 OQS00209.1 - 3.4e-48 163.7 0.2 1.9e-47 161.3 0.1 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OQS00209.1 - 2.4e-31 108.3 0.1 2.4e-31 108.3 0.1 2.5 3 0 0 3 3 3 1 Helicase conserved C-terminal domain CMS1 PF14617.6 OQS00209.1 - 0.0021 17.4 0.1 0.0021 17.4 0.1 3.4 3 1 0 3 3 3 1 U3-containing 90S pre-ribosomal complex subunit Homeobox_KN PF05920.11 OQS00210.1 - 1.2e-16 60.3 0.2 3.1e-16 59.0 0.0 1.9 2 0 0 2 2 2 1 Homeobox KN domain Homeodomain PF00046.29 OQS00210.1 - 9.2e-09 35.0 0.1 2.1e-08 33.8 0.1 1.6 1 0 0 1 1 1 1 Homeodomain GTP_EFTU PF00009.27 OQS00211.1 - 2.4e-58 196.9 0.1 4.6e-58 196.0 0.1 1.5 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 OQS00211.1 - 1.6e-36 124.8 0.1 3e-36 123.9 0.1 1.5 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_II PF14492.6 OQS00211.1 - 6e-32 109.6 0.0 1.5e-31 108.3 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.24 OQS00211.1 - 2.8e-27 94.6 0.1 8.7e-27 93.0 0.1 1.9 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 OQS00211.1 - 7.6e-11 42.2 0.0 2.7e-10 40.5 0.0 2.0 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RF3_C PF16658.5 OQS00211.1 - 2.7e-06 27.2 0.0 7.3e-06 25.8 0.0 1.7 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain AvrPtoB_bdg PF16847.5 OQS00211.1 - 0.00025 21.4 0.0 0.075 13.5 0.0 2.7 2 0 0 2 2 2 1 Avirulence AvrPtoB, BAK1-binding domain MMR_HSR1 PF01926.23 OQS00211.1 - 0.0018 18.3 0.1 0.0041 17.2 0.1 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.16 OQS00211.1 - 0.017 14.5 0.0 0.041 13.2 0.0 1.6 1 0 0 1 1 1 0 AIG1 family DUF442 PF04273.13 OQS00211.1 - 0.018 15.1 0.0 3.5 7.8 0.0 2.9 2 0 0 2 2 2 0 Putative phosphatase (DUF442) Peptidase_C12 PF01088.21 OQS00212.1 - 1.3e-58 198.3 0.0 1.4e-58 198.1 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 Synaphin PF05835.12 OQS00212.1 - 0.21 11.9 1.4 0.77 10.0 0.8 1.7 1 1 1 2 2 2 0 Synaphin protein Lyase_1 PF00206.20 OQS00213.1 - 7.5e-113 377.0 0.0 1e-112 376.6 0.0 1.2 1 0 0 1 1 1 1 Lyase FumaraseC_C PF10415.9 OQS00213.1 - 1.6e-25 89.2 0.1 3.6e-25 88.1 0.1 1.6 1 0 0 1 1 1 1 Fumarase C C-terminus Nucleoporin_FG PF13634.6 OQS00213.1 - 3.2e-25 88.8 77.6 0.0041 17.9 1.5 10.4 4 4 3 8 8 8 8 Nucleoporin FG repeat region Nop14 PF04147.12 OQS00213.1 - 0.088 11.0 16.5 0.13 10.4 16.5 1.2 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 OQS00213.1 - 0.32 9.2 10.3 0.47 8.7 10.3 1.2 1 0 0 1 1 1 0 CDC45-like protein Presenilin PF01080.17 OQS00213.1 - 1.1 7.9 5.1 1.8 7.2 5.1 1.2 1 0 0 1 1 1 0 Presenilin SopA_C PF13979.6 OQS00213.1 - 1.2 8.9 3.1 1.3 8.7 0.2 2.6 3 0 0 3 3 3 0 SopA-like catalytic domain SDA1 PF05285.12 OQS00213.1 - 1.6 8.0 19.6 0.028 13.9 12.2 1.7 2 0 0 2 2 2 0 SDA1 Paf1 PF03985.13 OQS00213.1 - 3.1 6.7 15.1 6.2 5.7 15.1 1.4 1 0 0 1 1 1 0 Paf1 Na_trans_assoc PF06512.13 OQS00213.1 - 3.8 7.7 17.9 21 5.3 18.7 1.8 2 0 0 2 2 2 0 Sodium ion transport-associated NHL PF01436.21 OQS00214.1 - 4e-11 42.4 10.0 3e-07 30.1 0.3 5.6 6 0 0 6 6 6 2 NHL repeat SGL PF08450.12 OQS00214.1 - 0.00023 20.8 1.5 1.7 8.2 0.0 3.8 2 2 1 3 3 3 2 SMP-30/Gluconolactonase/LRE-like region SBBP PF06739.11 OQS00214.1 - 0.00098 19.1 7.5 0.55 10.3 0.1 5.0 5 0 0 5 5 5 2 Beta-propeller repeat US22 PF02393.16 OQS00214.1 - 0.039 14.2 0.2 30 4.9 0.0 3.4 2 1 1 3 3 3 0 US22 like Peptidase_M1 PF01433.20 OQS00215.1 - 1.4e-81 273.3 6.5 1.4e-81 273.3 6.5 2.1 2 0 0 2 2 2 1 Peptidase family M1 domain ERAP1_C PF11838.8 OQS00215.1 - 2.5e-61 208.0 4.3 6.1e-61 206.7 3.3 2.1 2 0 0 2 2 2 1 ERAP1-like C-terminal domain TPP_enzyme_N PF02776.18 OQS00215.1 - 1.7e-53 180.7 0.0 6.9e-53 178.8 0.0 2.1 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 OQS00215.1 - 6.6e-48 162.4 1.0 1.9e-46 157.6 0.2 3.0 3 0 0 3 3 3 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 OQS00215.1 - 4.3e-44 149.6 0.3 1.4e-43 147.9 0.1 1.9 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain Peptidase_M1_N PF17900.1 OQS00215.1 - 4.5e-38 131.3 0.2 9.6e-38 130.2 0.2 1.6 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain Kelch_4 PF13418.6 OQS00216.1 - 2.7e-22 78.5 0.3 5.4e-07 29.5 0.0 6.6 7 1 0 7 7 7 3 Galactose oxidase, central domain Kelch_5 PF13854.6 OQS00216.1 - 2.4e-11 43.4 4.7 0.00042 20.2 0.1 5.6 5 1 0 5 5 5 3 Kelch motif Kelch_3 PF13415.6 OQS00216.1 - 3.3e-11 43.2 0.7 0.1 12.9 0.0 5.8 6 0 0 6 6 6 3 Galactose oxidase, central domain Kelch_6 PF13964.6 OQS00216.1 - 9e-10 38.5 4.5 0.9 9.9 0.1 6.2 5 1 0 5 5 5 3 Kelch motif Kelch_1 PF01344.25 OQS00216.1 - 9.3e-05 21.9 2.6 0.2 11.2 0.0 4.7 5 0 0 5 5 5 1 Kelch motif Kelch_2 PF07646.15 OQS00216.1 - 0.00016 21.5 0.5 1.9 8.6 0.0 4.8 5 1 0 5 5 5 1 Kelch motif RAG2 PF03089.14 OQS00216.1 - 0.065 12.2 0.0 7.9 5.4 0.0 2.8 3 0 0 3 3 3 0 Recombination activating protein 2 Glutaredoxin PF00462.24 OQS00217.1 - 2e-16 59.9 0.0 5.7e-16 58.5 0.0 1.7 2 0 0 2 2 2 1 Glutaredoxin DUF836 PF05768.14 OQS00217.1 - 0.0033 17.8 0.2 0.0048 17.3 0.2 1.3 1 0 0 1 1 1 1 Glutaredoxin-like domain (DUF836) Mak10 PF04112.13 OQS00218.1 - 9.4e-17 61.0 0.1 2.1e-16 59.9 0.1 1.5 1 0 0 1 1 1 1 Mak10 subunit, NatC N(alpha)-terminal acetyltransferase SIN1_PH PF16979.5 OQS00219.1 - 2.9e-10 40.4 0.6 6.3e-10 39.3 0.6 1.6 1 0 0 1 1 1 1 SAPK-interacting protein 1 (Sin1), Pleckstrin-homology CRIM PF16978.5 OQS00219.1 - 5e-10 39.7 0.0 1.2e-09 38.4 0.0 1.6 1 0 0 1 1 1 1 SAPK-interacting protein 1 (Sin1), middle CRIM domain RBD PF02196.15 OQS00219.1 - 0.00035 20.6 0.0 1.4 9.1 0.0 2.5 2 0 0 2 2 2 2 Raf-like Ras-binding domain Gag_spuma PF03276.14 OQS00219.1 - 0.79 8.1 3.9 1.2 7.5 3.9 1.1 1 0 0 1 1 1 0 Spumavirus gag protein Ribosomal_L18 PF17135.4 OQS00220.1 - 4.5e-86 287.0 2.7 5e-86 286.9 2.7 1.0 1 0 0 1 1 1 1 Ribosomal protein 60S L18 and 50S L18e Ribosomal_L27A PF00828.19 OQS00220.1 - 0.0061 17.2 0.1 0.015 15.9 0.1 1.7 1 1 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A SOG2 PF10428.9 OQS00221.1 - 0.62 9.2 15.2 0.76 8.9 15.2 1.0 1 0 0 1 1 1 0 RAM signalling pathway protein Apt1 PF10351.9 OQS00221.1 - 5.5 5.7 12.5 6.4 5.5 12.5 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain DUF1640 PF07798.11 OQS00222.1 - 0.00075 19.6 7.9 0.005 16.9 7.9 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF1640) Bac_DNA_binding PF00216.21 OQS00222.1 - 0.065 13.4 2.8 0.6 10.4 0.1 2.7 2 1 1 3 3 3 0 Bacterial DNA-binding protein Activator-TraM PF11657.8 OQS00223.1 - 0.21 11.4 4.8 1.3 8.9 1.0 2.6 2 1 0 3 3 3 0 Transcriptional activator TraM ATP-synt_D PF01813.17 OQS00224.1 - 0.31 10.8 10.7 0.43 10.4 3.4 2.3 2 0 0 2 2 2 0 ATP synthase subunit D HAUS-augmin3 PF14932.6 OQS00224.1 - 2.4 7.7 17.6 4.4 6.8 12.2 2.4 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 3 Vps5 PF09325.10 OQS00225.1 - 0.00038 20.1 6.5 0.26 10.8 0.2 3.5 3 0 0 3 3 3 2 Vps5 C terminal like PAE PF03283.13 OQS00225.1 - 0.11 11.6 0.2 7.4 5.6 0.3 2.3 2 0 0 2 2 2 0 Pectinacetylesterase CRISPR_assoc PF08798.11 OQS00225.1 - 0.16 12.1 0.0 0.16 12.1 0.0 2.6 3 0 0 3 3 3 0 CRISPR associated protein bZIP_1 PF00170.21 OQS00226.1 - 0.00043 20.3 2.4 0.00077 19.5 2.4 1.3 1 0 0 1 1 1 1 bZIP transcription factor BLOC1_2 PF10046.9 OQS00226.1 - 0.045 14.1 0.1 0.091 13.1 0.1 1.5 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF4618 PF15397.6 OQS00226.1 - 0.22 10.9 1.5 0.33 10.4 0.3 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4618) DUF4547 PF15080.6 OQS00227.1 - 0.03 14.0 0.0 0.053 13.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4547) DUF1778 PF08681.11 OQS00228.1 - 0.0044 16.9 3.5 0.0044 16.9 3.5 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF1778) UPF0242 PF06785.11 OQS00228.1 - 0.33 11.1 5.0 0.65 10.1 5.0 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus FadA PF09403.10 OQS00228.1 - 0.44 11.1 9.4 0.074 13.5 5.0 2.1 2 0 0 2 2 2 0 Adhesion protein FadA LacI PF00356.21 OQS00228.1 - 0.46 10.3 2.1 0.67 9.8 0.0 2.4 3 1 1 4 4 4 0 Bacterial regulatory proteins, lacI family DUF29 PF01724.16 OQS00228.1 - 0.5 10.6 5.8 0.8 9.9 4.2 2.1 2 1 0 2 2 2 0 Domain of unknown function DUF29 Glyco_hydro_31 PF01055.26 OQS00229.1 - 2.8e-140 468.4 3.8 3.5e-140 468.1 3.8 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 NtCtMGAM_N PF16863.5 OQS00229.1 - 1.2e-24 86.8 0.0 2e-24 86.0 0.0 1.4 1 0 0 1 1 1 1 N-terminal barrel of NtMGAM and CtMGAM, maltase-glucoamylase Trefoil PF00088.18 OQS00229.1 - 1.6e-09 37.5 23.0 8.8e-06 25.5 4.3 2.8 3 0 0 3 3 3 2 Trefoil (P-type) domain Gal_mutarotas_2 PF13802.6 OQS00229.1 - 1.3e-07 31.8 1.1 2.4e-07 30.9 0.2 1.9 2 0 0 2 2 2 1 Galactose mutarotase-like Ank_2 PF12796.7 OQS00230.1 - 5e-29 100.7 0.8 9.4e-16 58.2 0.1 3.7 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.30 OQS00230.1 - 7.3e-29 98.9 0.7 2e-10 40.7 0.0 6.1 6 0 0 6 6 6 5 Ankyrin repeat Ank_4 PF13637.6 OQS00230.1 - 2.7e-23 82.0 2.0 1.3e-12 48.0 0.2 4.7 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 OQS00230.1 - 3.7e-23 81.3 2.1 2.9e-09 37.0 0.0 5.0 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQS00230.1 - 5.1e-20 69.4 5.0 3.1e-08 33.3 0.0 5.8 6 0 0 6 6 6 3 Ankyrin repeat Peptidase_S41 PF03572.18 OQS00231.1 - 2.6e-09 36.9 0.0 6.2e-09 35.6 0.0 1.6 1 1 0 1 1 1 1 Peptidase family S41 ABC_tran PF00005.27 OQS00232.1 - 3.6e-28 98.8 0.1 7.7e-28 97.7 0.0 1.6 2 0 0 2 2 1 1 ABC transporter ABC_membrane PF00664.23 OQS00232.1 - 2e-26 93.3 7.8 2e-26 93.3 7.8 1.8 2 0 0 2 2 1 1 ABC transporter transmembrane region SMC_N PF02463.19 OQS00232.1 - 6.8e-07 28.9 0.2 5.9e-05 22.6 0.2 2.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 OQS00232.1 - 3.4e-06 27.0 0.0 8.6e-06 25.8 0.0 1.6 1 0 0 1 1 1 1 RsgA GTPase ABC_ATPase PF09818.9 OQS00232.1 - 7.1e-05 21.8 0.1 0.041 12.7 0.0 2.2 2 0 0 2 2 2 2 Predicted ATPase of the ABC class Septin PF00735.18 OQS00232.1 - 0.00013 21.4 0.0 0.00022 20.6 0.0 1.3 1 0 0 1 1 1 1 Septin AAA_21 PF13304.6 OQS00232.1 - 0.00014 21.8 0.1 0.23 11.2 0.0 2.3 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system Herpes_Helicase PF02689.14 OQS00232.1 - 0.00017 19.7 0.0 0.00026 19.1 0.0 1.2 1 0 0 1 1 1 1 Helicase AAA_22 PF13401.6 OQS00232.1 - 0.00046 20.5 0.2 0.0042 17.4 0.2 2.3 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 OQS00232.1 - 0.0005 20.5 0.1 0.0019 18.6 0.1 2.2 1 1 0 1 1 1 1 AAA ATPase domain AAA_23 PF13476.6 OQS00232.1 - 0.0058 17.2 0.0 0.011 16.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 OQS00232.1 - 0.013 15.2 0.0 0.036 13.8 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA PF00004.29 OQS00232.1 - 0.032 14.6 0.1 0.2 12.1 0.1 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) MMR_HSR1 PF01926.23 OQS00232.1 - 0.034 14.2 0.0 0.12 12.5 0.0 1.9 1 0 0 1 1 1 0 50S ribosome-binding GTPase ATP-synt_ab PF00006.25 OQS00232.1 - 0.056 13.1 0.1 0.12 12.0 0.1 1.4 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain RNA_helicase PF00910.22 OQS00232.1 - 0.064 13.6 0.0 0.19 12.1 0.0 1.8 1 0 0 1 1 1 0 RNA helicase SbcCD_C PF13558.6 OQS00232.1 - 0.065 13.5 0.1 0.27 11.5 0.1 2.1 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_15 PF13175.6 OQS00232.1 - 0.068 12.9 0.0 0.11 12.1 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain AAA_24 PF13479.6 OQS00232.1 - 0.091 12.5 0.1 0.22 11.2 0.1 1.6 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 OQS00232.1 - 0.13 12.2 0.4 0.56 10.1 0.0 2.1 2 0 0 2 2 2 0 NACHT domain AAA_25 PF13481.6 OQS00232.1 - 0.19 11.3 0.5 0.86 9.1 0.1 2.1 2 0 0 2 2 2 0 AAA domain SPRY PF00622.28 OQS00234.1 - 8.3e-14 51.7 0.1 1.4e-13 51.0 0.1 1.3 1 0 0 1 1 1 1 SPRY domain F-box PF00646.33 OQS00234.1 - 0.00021 21.1 0.1 0.00048 19.9 0.1 1.5 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 OQS00234.1 - 0.0011 18.9 0.0 0.0035 17.2 0.0 1.9 1 0 0 1 1 1 1 F-box-like PCI PF01399.27 OQS00235.1 - 7.4e-08 32.9 0.0 1.8e-07 31.7 0.0 1.6 1 0 0 1 1 1 1 PCI domain ISG65-75 PF11727.8 OQS00235.1 - 0.032 13.5 0.1 0.045 13.0 0.1 1.1 1 0 0 1 1 1 0 Invariant surface glycoprotein CSN7a_helixI PF18392.1 OQS00235.1 - 0.039 13.9 0.3 0.068 13.1 0.3 1.4 1 0 0 1 1 1 0 COP9 signalosome complex subunit 7a helix I domain Phage_TTP_1 PF04630.12 OQS00235.1 - 0.053 12.8 0.1 0.11 11.9 0.1 1.5 1 0 0 1 1 1 0 Phage tail tube protein MIP-T3_C PF17749.1 OQS00235.1 - 0.15 12.0 1.1 0.3 11.0 1.1 1.4 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 C-terminal region DUF4203 PF13886.6 OQS00238.1 - 4.7e-11 42.7 26.0 1.4e-10 41.2 26.0 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF4203) AzlD PF05437.12 OQS00239.1 - 0.54 10.5 5.0 3.4 7.9 0.1 3.3 3 0 0 3 3 3 0 Branched-chain amino acid transport protein (AzlD) Glyco_hydro81C PF17652.1 OQS00240.1 - 1.4e-114 383.0 7.0 1.4e-114 383.0 7.0 1.9 2 0 0 2 2 2 1 Glycosyl hydrolase family 81 C-terminal domain Glyco_hydro_81 PF03639.13 OQS00240.1 - 4e-41 141.3 0.1 6e-41 140.7 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 N-terminal domain Ank_2 PF12796.7 OQS00241.1 - 1.8e-09 38.1 7.8 2.3e-05 24.9 0.5 2.4 1 1 2 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQS00241.1 - 3.1e-07 30.8 1.5 0.00027 21.5 0.3 2.9 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 OQS00241.1 - 0.00021 21.5 2.1 0.13 12.6 0.1 2.7 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQS00241.1 - 0.0013 19.0 4.0 0.54 11.0 0.1 3.8 4 0 0 4 4 4 1 Ankyrin repeat Ank PF00023.30 OQS00241.1 - 0.083 13.4 1.4 1.8 9.1 0.1 2.9 1 1 1 2 2 2 0 Ankyrin repeat BK_channel_a PF03493.18 OQS00242.1 - 2.3e-18 66.2 0.0 2.6e-17 62.8 0.0 2.4 2 0 0 2 2 2 1 Calcium-activated BK potassium channel alpha subunit Ion_trans_2 PF07885.16 OQS00242.1 - 2.9e-12 46.4 1.0 2.9e-12 46.4 1.0 2.4 2 0 0 2 2 2 1 Ion channel Ion_trans PF00520.31 OQS00242.1 - 2.4e-11 43.4 10.2 4.2e-11 42.6 10.2 1.4 1 0 0 1 1 1 1 Ion transport protein TrkA_N PF02254.18 OQS00242.1 - 2.8e-06 27.6 0.0 0.0069 16.6 0.0 2.5 2 0 0 2 2 2 2 TrkA-N domain DUF973 PF06157.11 OQS00242.1 - 0.45 9.5 5.9 0.13 11.3 1.1 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF973) Cellulase PF00150.18 OQS00243.1 - 5.2e-21 75.3 0.6 1.1e-20 74.2 0.6 1.5 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Ricin_B_lectin PF00652.22 OQS00243.1 - 2.9e-19 69.6 18.7 2e-09 37.8 5.0 3.1 2 1 1 3 3 3 3 Ricin-type beta-trefoil lectin domain Tox-PLDMTX PF15645.6 OQS00243.1 - 0.045 14.0 1.2 0.12 12.7 0.3 2.1 2 0 0 2 2 2 0 Dermonecrotoxin of the Papain-like fold DUF3883 PF13020.6 OQS00244.1 - 1.7e-18 66.4 0.0 3.9e-18 65.3 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3883) Cwf_Cwc_15 PF04889.12 OQS00244.1 - 4.6 6.9 8.4 12 5.6 8.4 1.6 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Glyoxalase PF00903.25 OQS00245.1 - 8.1e-06 26.0 0.0 1.7e-05 25.0 0.0 1.5 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 OQS00245.1 - 0.00014 22.1 0.0 0.00029 21.1 0.0 1.6 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily F-box-like PF12937.7 OQS00245.1 - 0.0028 17.5 0.6 0.012 15.5 0.2 2.3 2 0 0 2 2 2 1 F-box-like Elongin_A PF06881.11 OQS00245.1 - 0.045 14.3 1.2 0.069 13.7 0.1 1.9 2 0 0 2 2 2 0 RNA polymerase II transcription factor SIII (Elongin) subunit A F-box PF00646.33 OQS00245.1 - 0.073 13.0 0.2 0.88 9.5 0.1 2.6 2 0 0 2 2 2 0 F-box domain RFX_DNA_binding PF02257.15 OQS00246.1 - 0.011 16.4 0.1 4.7 7.9 0.0 2.5 2 0 0 2 2 2 0 RFX DNA-binding domain LicD PF04991.13 OQS00247.1 - 0.0038 17.4 0.1 0.013 15.7 0.1 1.9 1 0 0 1 1 1 1 LicD family Phage_GP20 PF06810.11 OQS00247.1 - 0.089 12.6 3.3 0.17 11.7 3.3 1.4 1 0 0 1 1 1 0 Phage minor structural protein GP20 PP2C PF00481.21 OQS00248.1 - 3.8e-36 125.0 0.0 4.3e-36 124.9 0.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 OQS00248.1 - 6.6e-05 22.9 0.0 0.01 15.8 0.0 2.2 2 0 0 2 2 2 2 Stage II sporulation protein E (SpoIIE) Transthyretin PF00576.21 OQS00251.1 - 1.4e-32 112.7 0.1 2.9e-32 111.6 0.0 1.6 2 0 0 2 2 2 1 HIUase/Transthyretin family FYVE PF01363.21 OQS00251.1 - 4.5e-15 55.5 9.1 4.5e-15 55.5 9.1 1.7 2 0 0 2 2 2 1 FYVE zinc finger Zf_RING PF16744.5 OQS00251.1 - 0.69 10.1 7.8 1.9 8.6 7.8 1.7 1 0 0 1 1 1 0 KIAA1045 RING finger zf-RING_5 PF14634.6 OQS00251.1 - 0.92 9.5 10.7 3.1 7.8 10.7 1.9 1 0 0 1 1 1 0 zinc-RING finger domain Arf PF00025.21 OQS00252.1 - 1.3e-76 256.0 0.1 1.4e-76 255.8 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 OQS00252.1 - 1e-15 58.0 0.0 1.5e-15 57.5 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 OQS00252.1 - 2.2e-13 50.2 0.0 2.5e-13 50.0 0.0 1.0 1 0 0 1 1 1 1 Ras family G-alpha PF00503.20 OQS00252.1 - 8.5e-13 48.2 0.1 6.6e-09 35.4 0.0 2.2 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.10 OQS00252.1 - 2.4e-10 40.1 0.0 3e-10 39.8 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 OQS00252.1 - 5.8e-09 35.6 0.0 6.8e-09 35.4 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 OQS00252.1 - 3.1e-07 30.5 0.0 5.3e-07 29.7 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 OQS00252.1 - 0.0017 17.9 0.7 0.013 15.1 0.7 2.0 1 1 0 1 1 1 1 Ferrous iron transport protein B AAA_18 PF13238.6 OQS00252.1 - 0.023 15.2 0.0 0.037 14.6 0.0 1.4 1 1 0 1 1 1 0 AAA domain GTP_EFTU PF00009.27 OQS00252.1 - 0.036 13.6 0.2 0.89 9.1 0.0 2.1 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain AAA_14 PF13173.6 OQS00252.1 - 0.086 12.9 0.2 0.37 10.8 0.0 1.8 1 1 1 2 2 2 0 AAA domain AT_hook PF02178.19 OQS00253.1 - 0.0012 18.5 13.5 0.88 9.7 0.3 4.7 3 0 0 3 3 3 3 AT hook motif MMPL PF03176.15 OQS00253.1 - 0.21 10.5 3.1 0.38 9.6 3.1 1.3 1 0 0 1 1 1 0 MMPL family Ank_2 PF12796.7 OQS00254.1 - 2.6e-51 172.1 8.5 8.7e-14 51.9 0.1 5.5 2 1 3 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQS00254.1 - 5.9e-44 147.9 14.4 2.6e-12 47.0 0.0 8.7 3 3 6 9 9 9 9 Ankyrin repeats (many copies) Pkinase PF00069.25 OQS00254.1 - 4e-39 134.6 0.5 2.8e-38 131.8 0.1 2.1 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQS00254.1 - 1.8e-36 125.8 0.2 4.9e-36 124.3 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase Ank_3 PF13606.6 OQS00254.1 - 3.2e-36 119.2 14.5 0.0025 18.2 0.1 10.7 10 1 1 11 11 11 7 Ankyrin repeat Ank PF00023.30 OQS00254.1 - 6.6e-32 108.6 18.8 2.3e-06 27.8 0.6 8.4 7 1 1 8 8 8 7 Ankyrin repeat Ank_5 PF13857.6 OQS00254.1 - 2.9e-30 103.9 15.1 0.00011 22.4 0.0 8.0 2 1 6 8 8 8 8 Ankyrin repeats (many copies) ABC1 PF03109.16 OQS00254.1 - 0.024 14.8 0.0 0.09 13.0 0.0 1.9 2 0 0 2 2 2 0 ABC1 family Haspin_kinase PF12330.8 OQS00254.1 - 0.042 12.8 0.1 0.2 10.6 0.1 2.0 1 1 0 1 1 1 0 Haspin like kinase domain Kdo PF06293.14 OQS00254.1 - 0.079 12.3 0.1 0.19 11.0 0.0 1.6 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Acetyltransf_3 PF13302.7 OQS00255.1 - 1.1e-14 55.3 0.1 1.5e-14 54.9 0.1 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 OQS00255.1 - 1.1e-05 25.7 0.1 3.2e-05 24.1 0.0 1.7 1 1 1 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.7 OQS00255.1 - 0.0076 16.4 0.0 0.011 15.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Thioredoxin PF00085.20 OQS00256.1 - 1.3e-22 79.7 0.1 3.4e-22 78.4 0.1 1.7 1 0 0 1 1 1 1 Thioredoxin Evr1_Alr PF04777.13 OQS00256.1 - 7.2e-13 48.9 0.4 7.2e-13 48.9 0.4 3.4 5 0 0 5 5 5 1 Erv1 / Alr family FIST PF08495.10 OQS00256.1 - 5.7e-12 46.0 0.0 1.7e-11 44.4 0.0 1.9 1 0 0 1 1 1 1 FIST N domain FYVE PF01363.21 OQS00256.1 - 8.7e-07 29.0 7.0 8.7e-07 29.0 7.0 2.4 3 0 0 3 3 3 1 FYVE zinc finger FIST_C PF10442.9 OQS00256.1 - 4.9e-05 23.3 0.0 0.00011 22.2 0.0 1.7 1 0 0 1 1 1 1 FIST C domain OST3_OST6 PF04756.13 OQS00256.1 - 0.00013 21.4 0.1 0.00027 20.4 0.1 1.4 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_8 PF13905.6 OQS00256.1 - 0.015 15.6 0.1 0.083 13.2 0.0 2.3 2 1 1 3 3 3 0 Thioredoxin-like FYVE_2 PF02318.16 OQS00256.1 - 0.21 11.8 5.0 0.95 9.7 5.0 2.2 1 0 0 1 1 1 0 FYVE-type zinc finger Pkinase_Tyr PF07714.17 OQS00257.1 - 4.7e-43 147.3 0.0 1.1e-31 110.1 0.0 3.1 2 1 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 OQS00257.1 - 1.5e-42 145.8 0.0 5.4e-33 114.5 0.0 3.0 2 1 0 2 2 2 2 Protein kinase domain Kinase-like PF14531.6 OQS00257.1 - 9.9e-07 28.3 0.0 0.031 13.6 0.0 2.3 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.14 OQS00257.1 - 6.8e-05 22.3 0.1 0.09 12.1 0.0 2.2 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family Metallophos PF00149.28 OQS00258.1 - 3.7e-29 102.7 0.4 6.1e-29 102.0 0.4 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase PPP5 PF08321.12 OQS00258.1 - 2.9e-27 94.8 0.0 6.1e-27 93.8 0.0 1.6 1 0 0 1 1 1 1 PPP5 TPR repeat region TPR_1 PF00515.28 OQS00258.1 - 1.7e-14 52.9 2.8 0.00013 21.6 0.2 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 OQS00258.1 - 1.3e-12 46.8 1.9 0.004 17.2 0.2 3.6 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.6 OQS00258.1 - 3.6e-07 29.9 4.8 0.11 12.8 0.0 3.9 4 0 0 4 4 3 3 Tetratricopeptide repeat TPR_16 PF13432.6 OQS00258.1 - 6.1e-05 23.6 2.9 0.018 15.7 0.8 2.6 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.6 OQS00258.1 - 9.8e-05 22.0 7.8 0.13 11.9 0.6 3.9 2 1 2 4 4 4 2 TPR repeat TPR_9 PF13371.6 OQS00258.1 - 0.00027 21.0 0.1 0.00082 19.5 0.1 1.8 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_15 PF13429.6 OQS00258.1 - 0.015 14.6 0.4 0.039 13.2 0.3 1.6 1 1 1 2 2 2 0 Tetratricopeptide repeat DUF3856 PF12968.7 OQS00258.1 - 0.035 14.2 0.6 1.1 9.4 0.3 2.8 1 1 1 2 2 2 0 Domain of Unknown Function (DUF3856) TPR_14 PF13428.6 OQS00258.1 - 0.046 14.5 3.3 3.5 8.7 0.0 3.5 1 1 3 4 4 4 0 Tetratricopeptide repeat BTAD PF03704.17 OQS00258.1 - 0.067 13.6 0.8 0.13 12.6 0.8 1.5 1 0 0 1 1 1 0 Bacterial transcriptional activator domain TPR_17 PF13431.6 OQS00258.1 - 0.08 13.3 1.2 0.96 10.0 0.1 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.6 OQS00258.1 - 0.13 13.0 0.4 28 5.6 0.1 2.9 3 0 0 3 3 2 0 Tetratricopeptide repeat SRP_TPR_like PF17004.5 OQS00258.1 - 0.16 12.0 1.2 0.29 11.2 1.2 1.4 1 0 0 1 1 1 0 Putative TPR-like repeat TPR_19 PF14559.6 OQS00258.1 - 0.18 12.4 5.3 0.082 13.4 0.9 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat HA PF03457.14 OQS00260.1 - 1.2e-42 144.1 4.2 1.4e-10 41.3 0.1 5.2 5 0 0 5 5 5 4 Helicase associated domain Dicer_dimer PF03368.14 OQS00260.1 - 0.044 13.9 0.0 12 6.2 0.0 3.8 5 0 0 5 5 5 0 Dicer dimerisation domain Gcd10p PF04189.13 OQS00261.1 - 1.6e-58 198.2 0.0 3.8e-58 197.0 0.0 1.6 1 1 1 2 2 2 1 Gcd10p family Fucose_iso_N2 PF07882.12 OQS00261.1 - 0.049 13.2 0.0 0.12 12.0 0.0 1.6 1 0 0 1 1 1 0 L-fucose isomerase, second N-terminal domain Glyco_hydro_18 PF00704.28 OQS00262.1 - 6e-70 236.4 4.6 7.7e-70 236.1 4.6 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 tRNA_Me_trans PF03054.16 OQS00262.1 - 0.011 14.6 0.0 0.017 13.9 0.0 1.2 1 0 0 1 1 1 0 tRNA methyl transferase DUF1965 PF09248.10 OQS00262.1 - 0.14 11.9 3.3 0.25 11.1 0.0 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF1965) Lung_7-TM_R PF06814.13 OQS00263.1 - 1.2e-41 142.9 19.5 2.1e-41 142.1 19.5 1.4 1 0 0 1 1 1 1 Lung seven transmembrane receptor EF-hand_1 PF00036.32 OQS00263.1 - 1.1e-20 71.6 4.8 2.7e-05 23.4 0.1 6.5 6 0 0 6 6 6 4 EF hand EF-hand_7 PF13499.6 OQS00263.1 - 3.8e-19 68.9 11.6 8.2e-07 29.4 0.3 4.9 5 0 0 5 5 5 3 EF-hand domain pair EF-hand_6 PF13405.6 OQS00263.1 - 2.5e-16 58.2 8.0 0.0012 18.7 0.1 6.3 6 0 0 6 6 6 4 EF-hand domain EF-hand_5 PF13202.6 OQS00263.1 - 9.8e-10 37.5 4.3 0.022 14.2 0.0 5.2 5 0 0 5 5 5 3 EF hand GpcrRhopsn4 PF10192.9 OQS00263.1 - 0.00021 20.8 15.7 0.00053 19.5 15.7 1.7 1 0 0 1 1 1 1 Rhodopsin-like GPCR transmembrane domain EF-hand_8 PF13833.6 OQS00263.1 - 0.0028 17.5 13.4 0.5 10.2 0.1 5.2 5 1 1 6 6 6 3 EF-hand domain pair EF-hand_4 PF12763.7 OQS00263.1 - 0.03 14.3 4.6 10 6.1 0.1 4.4 3 1 1 4 4 4 0 Cytoskeletal-regulatory complex EF hand AhpC-TSA PF00578.21 OQS00264.1 - 2.8e-38 130.6 0.0 5.3e-38 129.7 0.0 1.5 2 0 0 2 2 2 1 AhpC/TSA family Redoxin PF08534.10 OQS00264.1 - 2.3e-16 59.8 0.0 3.1e-16 59.4 0.0 1.2 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.9 OQS00264.1 - 1.1e-12 47.6 0.1 2e-12 46.7 0.1 1.4 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin SCO1-SenC PF02630.14 OQS00264.1 - 0.026 14.4 0.0 0.076 12.9 0.0 1.7 3 0 0 3 3 3 0 SCO1/SenC Methyltr_RsmB-F PF01189.17 OQS00265.1 - 1.2e-21 77.3 0.3 1.9e-21 76.6 0.3 1.3 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F FtsJ PF01728.19 OQS00265.1 - 0.00024 21.2 0.1 0.012 15.7 0.1 2.3 1 1 1 2 2 2 1 FtsJ-like methyltransferase Methyltr_RsmF_N PF17125.5 OQS00265.1 - 0.033 14.7 0.0 0.087 13.3 0.0 1.8 1 0 0 1 1 1 0 N-terminal domain of 16S rRNA methyltransferase RsmF WIYLD PF10440.9 OQS00265.1 - 0.13 12.1 0.0 21 5.0 0.0 2.6 2 0 0 2 2 2 0 Ubiquitin-binding WIYLD domain DUF1279 PF06916.13 OQS00267.1 - 0.02 15.4 0.0 0.036 14.6 0.0 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1279) DivIC PF04977.15 OQS00267.1 - 0.076 12.8 0.2 0.14 11.9 0.2 1.4 1 0 0 1 1 1 0 Septum formation initiator HALZ PF02183.18 OQS00267.1 - 0.48 10.7 4.0 0.8 10.0 4.0 1.3 1 0 0 1 1 1 0 Homeobox associated leucine zipper PAPS_reduct PF01507.19 OQS00268.1 - 1.7e-25 90.1 0.1 2.5e-16 60.2 0.0 2.5 1 1 1 2 2 2 2 Phosphoadenosine phosphosulfate reductase family FYVE PF01363.21 OQS00268.1 - 6.9e-13 48.5 14.0 1.8e-12 47.2 14.0 1.7 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.16 OQS00268.1 - 0.0085 16.3 9.2 0.014 15.6 7.8 2.0 2 0 0 2 2 2 1 FYVE-type zinc finger VRP3 PF03536.15 OQS00268.1 - 0.044 13.3 0.1 0.078 12.5 0.1 1.3 1 0 0 1 1 1 0 Salmonella virulence-associated 28kDa protein HypA PF01155.19 OQS00268.1 - 9.4 6.3 7.7 6.6 6.8 3.0 2.4 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA CMAS PF02353.20 OQS00269.1 - 7.7e-89 297.6 0.8 9.4e-89 297.3 0.8 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_25 PF13649.6 OQS00269.1 - 8.9e-15 55.2 0.0 1.9e-14 54.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OQS00269.1 - 1.1e-11 45.2 0.0 2.1e-11 44.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OQS00269.1 - 3.7e-11 43.0 0.0 5.6e-11 42.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OQS00269.1 - 1.8e-10 40.9 0.0 3.1e-10 40.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OQS00269.1 - 2.5e-09 37.7 0.0 4.8e-09 36.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 OQS00269.1 - 7e-06 25.7 0.0 1.1e-05 25.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Ubie_methyltran PF01209.18 OQS00269.1 - 0.00022 20.7 0.0 0.00035 20.0 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_15 PF09445.10 OQS00269.1 - 0.00024 20.7 0.1 0.00035 20.2 0.1 1.4 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase TehB PF03848.14 OQS00269.1 - 0.0005 19.5 0.0 0.00078 18.9 0.0 1.2 1 0 0 1 1 1 1 Tellurite resistance protein TehB PCMT PF01135.19 OQS00269.1 - 0.0028 17.4 0.0 0.0048 16.7 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_32 PF13679.6 OQS00269.1 - 0.003 17.6 0.0 0.0051 16.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 OQS00269.1 - 0.0099 15.3 0.0 0.016 14.7 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) ADH_zinc_N PF00107.26 OQS00269.1 - 0.028 14.4 0.0 0.069 13.1 0.0 1.7 1 0 0 1 1 1 0 Zinc-binding dehydrogenase Methyltransf_8 PF05148.15 OQS00269.1 - 0.044 13.6 0.0 1.8 8.3 0.0 2.3 2 0 0 2 2 2 0 Hypothetical methyltransferase Methyltransf_16 PF10294.9 OQS00269.1 - 0.085 12.6 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 Lysine methyltransferase RrnaAD PF00398.20 OQS00269.1 - 0.088 11.9 0.0 0.32 10.0 0.0 1.8 1 1 0 1 1 1 0 Ribosomal RNA adenine dimethylase MetW PF07021.12 OQS00269.1 - 0.11 12.1 0.0 0.18 11.4 0.0 1.4 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Pyridox_oxase_2 PF12766.7 OQS00270.1 - 5.7e-25 87.8 0.0 9.3e-25 87.2 0.0 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Putative_PNPOx PF01243.20 OQS00270.1 - 6.3e-11 42.3 0.0 1.1e-10 41.6 0.0 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pyrid_ox_like PF16242.5 OQS00270.1 - 0.072 12.7 0.0 0.2 11.2 0.0 1.6 2 0 0 2 2 2 0 Pyridoxamine 5'-phosphate oxidase like SNF2_N PF00176.23 OQS00271.1 - 3e-70 236.7 2.1 4e-70 236.3 0.8 1.9 2 0 0 2 2 2 1 SNF2 family N-terminal domain SLIDE PF09111.10 OQS00271.1 - 1.9e-33 114.8 2.0 5.3e-33 113.5 0.3 2.8 2 0 0 2 2 2 1 SLIDE Helicase_C PF00271.31 OQS00271.1 - 9.2e-20 71.1 0.0 5e-19 68.7 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain HMG_box_2 PF09011.10 OQS00271.1 - 1.9e-09 38.0 0.2 1.9e-09 38.0 0.2 2.7 2 0 0 2 2 1 1 HMG-box domain ResIII PF04851.15 OQS00271.1 - 4.7e-09 36.5 0.0 4.7e-09 36.5 0.0 3.0 5 0 0 5 5 5 1 Type III restriction enzyme, res subunit HMG_box PF00505.19 OQS00271.1 - 3.6e-07 30.5 0.0 3.6e-07 30.5 0.0 2.3 2 0 0 2 2 1 1 HMG (high mobility group) box Myb_DNA-binding PF00249.31 OQS00271.1 - 4.6e-07 29.9 0.0 7.6e-06 26.0 0.0 2.7 2 0 0 2 2 2 1 Myb-like DNA-binding domain HDA2-3 PF11496.8 OQS00271.1 - 6.3e-05 22.3 0.1 6.3e-05 22.3 0.1 1.9 2 0 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 DEAD PF00270.29 OQS00271.1 - 0.00012 21.9 0.0 0.00061 19.6 0.0 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase Myb_DNA-bind_6 PF13921.6 OQS00271.1 - 0.00068 19.8 0.9 0.0082 16.4 0.0 3.5 4 0 0 4 4 3 1 Myb-like DNA-binding domain AAA_22 PF13401.6 OQS00271.1 - 0.22 11.8 1.7 6 7.2 0.0 3.7 4 0 0 4 4 4 0 AAA domain FYVE PF01363.21 OQS00272.1 - 1.4e-24 86.0 80.0 8.3e-11 41.9 9.9 6.9 8 0 0 8 8 8 5 FYVE zinc finger FYVE_2 PF02318.16 OQS00272.1 - 0.00083 19.6 50.9 0.079 13.2 7.1 4.7 4 0 0 4 4 4 3 FYVE-type zinc finger p450 PF00067.22 OQS00273.1 - 8.9e-60 202.7 0.0 1.1e-59 202.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Glyco_hydro_14 PF01373.17 OQS00274.1 - 4.6e-92 309.1 4.3 6.3e-92 308.6 4.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 14 BK_channel_a PF03493.18 OQS00274.1 - 3.6e-14 52.7 0.0 9.5e-14 51.4 0.0 1.8 1 0 0 1 1 1 1 Calcium-activated BK potassium channel alpha subunit Ion_trans PF00520.31 OQS00274.1 - 6.8e-14 51.7 3.3 1.5e-13 50.6 3.3 1.5 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 OQS00274.1 - 4.5e-12 45.8 1.3 1.5e-11 44.1 1.3 2.0 1 0 0 1 1 1 1 Ion channel TrkA_N PF02254.18 OQS00274.1 - 3.3e-05 24.1 0.0 0.0013 19.0 0.0 2.4 2 0 0 2 2 2 1 TrkA-N domain DUF956 PF06115.11 OQS00274.1 - 0.0095 15.6 0.1 0.033 13.9 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF956) CH PF00307.31 OQS00275.1 - 5.1e-08 33.1 0.6 2.4e-06 27.7 0.2 2.6 2 1 0 2 2 2 1 Calponin homology (CH) domain CAMSAP_CH PF11971.8 OQS00275.1 - 0.0025 17.6 0.0 0.0063 16.3 0.0 1.6 1 0 0 1 1 1 1 CAMSAP CH domain CH_2 PF06294.11 OQS00275.1 - 0.01 16.0 0.5 0.025 14.7 0.2 1.9 2 0 0 2 2 2 0 CH-like domain in sperm protein GCK PF07802.11 OQS00275.1 - 0.058 13.8 0.3 0.15 12.5 0.3 1.7 1 0 0 1 1 1 0 GCK domain FYVE PF01363.21 OQS00276.1 - 3.2 8.0 10.8 1.1 9.4 7.9 1.7 2 0 0 2 2 2 0 FYVE zinc finger PP2C PF00481.21 OQS00277.1 - 6e-49 167.0 0.1 3.2e-48 164.6 0.1 2.0 1 1 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 OQS00277.1 - 5e-06 26.3 0.6 3.6e-05 23.5 0.1 2.3 2 1 0 2 2 2 1 Protein phosphatase 2C FYVE PF01363.21 OQS00278.1 - 3.5e-09 36.7 10.1 3.5e-09 36.7 10.1 1.9 2 0 0 2 2 2 1 FYVE zinc finger FYVE_2 PF02318.16 OQS00278.1 - 0.0024 18.1 5.2 0.0024 18.1 5.2 2.3 2 0 0 2 2 2 1 FYVE-type zinc finger DZR PF12773.7 OQS00278.1 - 2.5 8.2 7.8 67 3.6 7.8 2.7 1 1 0 1 1 1 0 Double zinc ribbon Rubis-subs-bind PF09273.11 OQS00279.1 - 2.2e-23 83.4 0.1 3.6e-23 82.7 0.1 1.4 1 0 0 1 1 1 1 Rubisco LSMT substrate-binding SET PF00856.28 OQS00279.1 - 5.9e-09 36.5 0.0 9.9e-09 35.8 0.0 1.4 1 0 0 1 1 1 1 SET domain DUF4435 PF14491.6 OQS00279.1 - 0.038 13.9 0.2 0.11 12.3 0.2 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF4435) WD40 PF00400.32 OQS00280.1 - 1.6e-17 63.5 7.7 1.3e-08 35.4 0.0 5.6 7 0 0 7 7 7 2 WD domain, G-beta repeat Ge1_WD40 PF16529.5 OQS00280.1 - 7.4e-10 38.3 2.9 0.0046 16.0 0.3 3.4 1 1 1 3 3 3 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Nucleoporin_N PF08801.11 OQS00280.1 - 6.3e-07 28.5 0.4 0.002 16.9 0.0 2.4 1 1 1 2 2 2 2 Nup133 N terminal like ANAPC4_WD40 PF12894.7 OQS00280.1 - 9.5e-06 25.8 0.0 0.83 10.0 0.0 4.8 3 1 3 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 OQS00280.1 - 0.00037 20.3 0.5 7.6 6.6 0.1 3.6 3 0 0 3 3 3 2 WD40-like Beta Propeller Repeat eIF2A PF08662.11 OQS00280.1 - 0.0057 16.6 2.5 1 9.2 0.0 3.8 3 2 1 4 4 4 1 Eukaryotic translation initiation factor eIF2A OAD_gamma PF04277.13 OQS00280.1 - 0.16 12.6 0.5 0.41 11.3 0.5 1.7 1 1 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain ABC_membrane PF00664.23 OQS00281.1 - 5e-22 78.8 25.5 7.1e-22 78.3 25.5 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region Peptidase_M48 PF01435.18 OQS00282.1 - 3.8e-23 82.3 0.0 1.1e-22 80.8 0.0 1.7 1 1 0 1 1 1 1 Peptidase family M48 Band_7 PF01145.25 OQS00283.1 - 2.9e-27 95.8 1.9 6.8e-27 94.6 1.9 1.7 1 0 0 1 1 1 1 SPFH domain / Band 7 family FYVE PF01363.21 OQS00283.1 - 1.3e-20 73.3 35.8 2.2e-11 43.7 12.5 2.8 2 1 0 2 2 2 2 FYVE zinc finger GAF PF01590.26 OQS00283.1 - 3.1e-10 40.8 0.0 0.0003 21.4 0.0 2.9 3 0 0 3 3 3 2 GAF domain GAF_2 PF13185.6 OQS00283.1 - 1.1e-09 38.7 0.0 0.00022 21.6 0.0 2.5 2 0 0 2 2 2 2 GAF domain SKG6 PF08693.10 OQS00283.1 - 0.00051 19.4 3.6 0.0011 18.3 3.6 1.4 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Med8 PF10232.9 OQS00284.1 - 7.7e-10 38.8 7.5 2e-09 37.4 7.5 1.6 1 1 0 1 1 1 1 Mediator of RNA polymerase II transcription complex subunit 8 Microcephalin PF12258.8 OQS00284.1 - 0.11 11.7 0.3 0.14 11.4 0.3 1.1 1 0 0 1 1 1 0 Microcephalin protein LRR_4 PF12799.7 OQS00285.1 - 0.0058 17.0 4.9 0.045 14.2 0.6 3.4 3 0 0 3 3 3 1 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 OQS00285.1 - 0.0069 16.1 5.5 0.051 13.3 0.8 3.2 3 1 2 5 5 5 3 Leucine rich repeat Ras PF00071.22 OQS00286.1 - 5.9e-64 214.6 0.6 6.8e-64 214.3 0.6 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OQS00286.1 - 3.9e-36 123.9 0.1 5.8e-36 123.3 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OQS00286.1 - 8.8e-16 57.8 0.0 1e-15 57.6 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 OQS00286.1 - 2.3e-06 27.7 0.0 3.6e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 OQS00286.1 - 4.9e-05 22.8 0.0 5.6e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 OQS00286.1 - 0.00012 22.0 0.3 0.069 13.1 0.0 2.6 1 1 2 3 3 3 2 RsgA GTPase GTP_EFTU PF00009.27 OQS00286.1 - 0.00013 21.6 0.3 0.00061 19.4 0.2 2.1 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 OQS00286.1 - 0.00088 18.7 0.5 0.0012 18.3 0.0 1.4 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit AAA_22 PF13401.6 OQS00286.1 - 0.0051 17.1 0.0 0.01 16.1 0.0 1.5 1 1 0 1 1 1 1 AAA domain CENP-M PF11111.8 OQS00286.1 - 0.013 14.7 0.0 0.02 14.1 0.0 1.2 1 0 0 1 1 1 0 Centromere protein M (CENP-M) AAA_16 PF13191.6 OQS00286.1 - 0.017 15.5 0.0 0.021 15.2 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain ABC_tran PF00005.27 OQS00286.1 - 0.041 14.4 0.1 0.11 13.0 0.0 2.0 1 1 0 1 1 1 0 ABC transporter DAP3 PF10236.9 OQS00286.1 - 0.082 12.1 0.0 0.14 11.3 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 NACHT PF05729.12 OQS00286.1 - 0.086 12.8 0.0 0.17 11.8 0.0 1.5 1 0 0 1 1 1 0 NACHT domain AAA_5 PF07728.14 OQS00286.1 - 0.15 12.0 0.0 0.25 11.3 0.0 1.7 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) FYVE PF01363.21 OQS00287.1 - 1.4e-12 47.5 10.9 3e-12 46.5 10.9 1.6 1 0 0 1 1 1 1 FYVE zinc finger GAF PF01590.26 OQS00287.1 - 0.00051 20.7 0.0 0.0011 19.7 0.0 1.5 1 0 0 1 1 1 1 GAF domain GAF_2 PF13185.6 OQS00287.1 - 0.0018 18.6 0.0 0.0032 17.8 0.0 1.4 1 0 0 1 1 1 1 GAF domain FYVE_2 PF02318.16 OQS00287.1 - 0.25 11.6 6.1 0.6 10.3 6.2 1.6 1 1 0 1 1 1 0 FYVE-type zinc finger 3-alpha PF03475.14 OQS00288.1 - 0.03 14.2 0.0 0.1 12.5 0.0 2.0 1 0 0 1 1 1 0 3-alpha domain TetR PF13972.6 OQS00288.1 - 0.11 12.1 1.3 1.7 8.3 0.0 3.1 3 2 0 3 3 3 0 Bacterial transcriptional repressor LRR_8 PF13855.6 OQS00289.1 - 1.8e-27 94.8 43.0 1e-10 41.2 2.7 4.4 1 1 4 5 5 5 5 Leucine rich repeat LRR_4 PF12799.7 OQS00289.1 - 1.9e-23 82.1 26.3 5.8e-07 29.7 3.1 5.4 3 1 3 6 6 6 6 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 OQS00289.1 - 1.5e-14 53.9 13.6 2.4e-07 30.4 0.7 3.0 1 1 2 3 3 3 3 Leucine-rich repeat LRR_6 PF13516.6 OQS00289.1 - 9.4e-09 34.6 24.8 0.91 9.7 0.4 8.7 8 0 0 8 8 8 3 Leucine Rich repeat LRR_5 PF13306.6 OQS00289.1 - 1.6e-05 24.9 0.6 0.16 11.9 0.2 2.4 1 1 1 2 2 2 2 BspA type Leucine rich repeat region (6 copies) LRR_1 PF00560.33 OQS00289.1 - 1.8e-05 24.6 18.1 1.1 10.1 0.2 7.7 9 0 0 9 9 9 2 Leucine Rich Repeat ECM1 PF05782.11 OQS00289.1 - 0.25 10.2 13.7 0.36 9.7 13.7 1.1 1 0 0 1 1 1 0 Extracellular matrix protein 1 (ECM1) CDC45 PF02724.14 OQS00289.1 - 2.1 6.5 20.6 3.2 5.9 20.6 1.2 1 0 0 1 1 1 0 CDC45-like protein SID-1_RNA_chan PF13965.6 OQS00289.1 - 3.4 6.0 5.4 4.2 5.7 5.4 1.3 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Peptidase_S64 PF08192.11 OQS00289.1 - 5.7 5.3 20.8 8.5 4.7 20.8 1.2 1 0 0 1 1 1 0 Peptidase family S64 TraQ PF09679.10 OQS00290.1 - 0.13 12.2 0.0 0.21 11.5 0.0 1.3 1 0 0 1 1 1 0 Type-F conjugative transfer system pilin chaperone (TraQ) Glyco_hydro_6 PF01341.17 OQS00291.1 - 6.8e-79 265.8 8.4 1.3e-46 159.8 2.4 3.0 2 1 1 3 3 3 2 Glycosyl hydrolases family 6 CBM_1 PF00734.18 OQS00291.1 - 2.5e-17 62.5 27.6 4.4e-09 36.1 9.8 3.2 2 0 0 2 2 2 2 Fungal cellulose binding domain PT PF04886.12 OQS00291.1 - 6.9e-15 54.3 104.1 1.4e-06 27.8 26.3 4.6 1 1 3 4 4 4 4 PT repeat Methyltransf_11 PF08241.12 OQS00292.1 - 4.2e-14 53.0 0.0 7e-14 52.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OQS00292.1 - 1.5e-12 48.0 0.0 2.7e-12 47.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OQS00292.1 - 1.1e-06 28.6 0.0 1.7e-06 27.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OQS00292.1 - 1.1e-05 26.0 0.0 2.9e-05 24.7 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OQS00292.1 - 0.0008 19.2 0.0 0.028 14.2 0.0 2.8 1 1 1 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 OQS00292.1 - 0.0024 17.2 0.0 0.0048 16.2 0.0 1.4 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family RrnaAD PF00398.20 OQS00292.1 - 0.042 12.9 0.0 0.082 12.0 0.0 1.4 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Lipase_GDSL_2 PF13472.6 OQS00293.1 - 1.2e-23 84.4 0.1 3.2e-23 83.1 0.1 1.7 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 OQS00293.1 - 3e-14 53.5 1.1 8.6e-14 52.0 0.0 2.4 2 1 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase KIX_2 PF16987.5 OQS00293.1 - 4.6e-08 32.9 0.2 3.2e-07 30.2 0.2 2.6 1 0 0 1 1 1 1 KIX domain DUF1589 PF07628.11 OQS00293.1 - 0.032 14.4 0.0 5 7.2 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1589) FCH PF00611.23 OQS00293.1 - 0.7 10.2 3.2 12 6.2 0.1 3.2 3 0 0 3 3 3 0 Fes/CIP4, and EFC/F-BAR homology domain DUF3560 PF12083.8 OQS00293.1 - 7.7 6.7 6.4 0.68 10.1 0.3 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF3560) DUF4968 PF16338.5 OQS00294.1 - 0.095 13.0 0.0 0.14 12.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4968) Ribosomal_L34e PF01199.18 OQS00295.1 - 1.9e-40 137.0 9.4 2.9e-40 136.5 9.4 1.3 1 0 0 1 1 1 1 Ribosomal protein L34e NinF PF05810.12 OQS00295.1 - 0.2 11.6 1.9 4 7.4 0.1 2.2 1 1 1 2 2 2 0 NinF protein FhuF_C PF11575.8 OQS00295.1 - 0.56 10.2 4.3 5.7 7.0 0.2 2.4 2 0 0 2 2 2 0 FhuF 2Fe-2S C-terminal domain Methyltransf_10 PF05971.12 OQS00296.1 - 1.4e-76 257.7 0.3 1.8e-75 254.1 0.3 2.2 1 1 0 1 1 1 1 RNA methyltransferase PrmA PF06325.13 OQS00296.1 - 2.4e-06 27.2 0.3 5.8e-06 25.9 0.0 1.7 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 OQS00296.1 - 3.8e-05 23.3 0.0 0.00015 21.3 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_12 PF08242.12 OQS00296.1 - 0.019 15.7 0.0 0.11 13.3 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase domain Met_10 PF02475.16 OQS00296.1 - 0.043 13.6 0.0 0.078 12.7 0.0 1.4 1 0 0 1 1 1 0 Met-10+ like-protein Methyltransf_18 PF12847.7 OQS00296.1 - 0.069 13.1 0.0 0.17 11.8 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.6 OQS00296.1 - 0.081 13.6 0.0 0.28 11.9 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_31 PF13847.6 OQS00296.1 - 0.1 12.4 0.0 0.24 11.2 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain AROS PF15684.5 OQS00296.1 - 2.1 8.9 12.6 5.1 7.7 12.2 1.9 2 0 0 2 2 2 0 Active regulator of SIRT1, or 40S ribosomal protein S19-binding 1 ABC_tran PF00005.27 OQS00298.1 - 2.4e-40 138.2 0.5 2.9e-21 76.4 0.0 4.1 3 2 0 3 3 2 2 ABC transporter AAA_21 PF13304.6 OQS00298.1 - 4.5e-17 62.8 0.0 5.8e-05 23.0 0.0 4.4 4 0 0 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 OQS00298.1 - 1.7e-09 37.5 0.0 0.064 12.7 0.0 4.0 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 OQS00298.1 - 8.6e-06 25.8 0.0 0.16 12.1 0.0 2.9 2 0 0 2 2 2 2 50S ribosome-binding GTPase NACHT PF05729.12 OQS00298.1 - 2.7e-05 24.2 0.0 0.34 10.8 0.0 2.9 2 0 0 2 2 2 2 NACHT domain AAA_28 PF13521.6 OQS00298.1 - 3.1e-05 24.3 0.0 0.62 10.3 0.0 3.5 3 0 0 3 3 3 2 AAA domain AAA_29 PF13555.6 OQS00298.1 - 3.6e-05 23.4 0.1 0.11 12.2 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 OQS00298.1 - 5.3e-05 23.5 1.3 0.9 9.8 0.0 3.8 3 0 0 3 3 3 2 AAA domain RsgA_GTPase PF03193.16 OQS00298.1 - 9.3e-05 22.4 0.0 0.23 11.4 0.0 2.6 2 0 0 2 2 2 2 RsgA GTPase DUF815 PF05673.13 OQS00298.1 - 0.0001 21.6 0.1 0.025 13.8 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF815) MeaB PF03308.16 OQS00298.1 - 0.00013 21.0 0.2 0.98 8.3 0.0 3.3 3 0 0 3 3 3 2 Methylmalonyl Co-A mutase-associated GTPase MeaB NB-ARC PF00931.22 OQS00298.1 - 0.00013 21.2 3.2 0.19 10.9 0.0 2.9 3 0 0 3 3 3 2 NB-ARC domain AAA_18 PF13238.6 OQS00298.1 - 0.00023 21.7 0.0 0.2 12.2 0.0 3.0 2 0 0 2 2 2 1 AAA domain Roc PF08477.13 OQS00298.1 - 0.00025 21.3 0.0 1.1 9.5 0.0 2.6 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase AAA_16 PF13191.6 OQS00298.1 - 0.00025 21.5 0.7 1.6 9.1 0.0 3.8 3 0 0 3 3 3 1 AAA ATPase domain ATP-synt_ab PF00006.25 OQS00298.1 - 0.0006 19.5 0.0 0.24 11.0 0.0 2.4 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain AAA_24 PF13479.6 OQS00298.1 - 0.00067 19.4 0.0 0.73 9.5 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.6 OQS00298.1 - 0.00084 19.5 0.0 2.7 8.1 0.0 3.1 2 0 0 2 2 2 2 AAA domain 4HB PF17947.1 OQS00298.1 - 0.001 19.0 0.0 0.0028 17.7 0.0 1.7 1 0 0 1 1 1 1 Four helical bundle domain AAA PF00004.29 OQS00298.1 - 0.0012 19.2 0.0 0.95 9.9 0.0 3.2 3 0 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) HEAT_EZ PF13513.6 OQS00298.1 - 0.0026 18.2 5.0 13 6.5 0.0 4.8 4 1 1 5 5 4 0 HEAT-like repeat AAA_25 PF13481.6 OQS00298.1 - 0.0037 16.9 0.7 0.26 10.8 0.0 2.8 3 0 0 3 3 2 1 AAA domain PduV-EutP PF10662.9 OQS00298.1 - 0.0042 16.8 0.0 0.87 9.3 0.0 2.6 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation RNA_helicase PF00910.22 OQS00298.1 - 0.0047 17.3 0.0 4.2 7.8 0.0 2.6 2 0 0 2 2 2 0 RNA helicase AAA_15 PF13175.6 OQS00298.1 - 0.0055 16.5 1.8 1.1 8.9 0.0 2.7 3 0 0 3 3 2 1 AAA ATPase domain AAA_14 PF13173.6 OQS00298.1 - 0.0087 16.1 0.0 4.6 7.3 0.0 2.9 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 OQS00298.1 - 0.011 15.4 0.0 6.7 6.4 0.0 2.8 3 0 0 3 3 2 0 AAA domain Vac14_Fab1_bd PF12755.7 OQS00298.1 - 0.015 15.9 0.0 9 7.0 0.0 3.4 2 1 1 3 3 2 0 Vacuolar 14 Fab1-binding region AAA_7 PF12775.7 OQS00298.1 - 0.02 14.4 0.0 5.6 6.4 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region NTPase_1 PF03266.15 OQS00298.1 - 0.028 14.3 0.2 7.7 6.4 0.1 2.7 2 0 0 2 2 2 0 NTPase TsaE PF02367.17 OQS00298.1 - 0.029 14.4 0.1 13 5.8 0.1 2.5 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ATP_bind_1 PF03029.17 OQS00298.1 - 0.047 13.5 0.0 8.9 6.0 0.0 2.7 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein DUF87 PF01935.17 OQS00298.1 - 0.064 13.3 6.7 0.14 12.2 0.0 3.3 3 0 0 3 3 3 0 Helicase HerA, central domain ATPase_2 PF01637.18 OQS00298.1 - 0.083 12.8 0.0 22 4.9 0.0 2.6 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea Septin PF00735.18 OQS00298.1 - 0.099 11.9 0.1 9.9 5.3 0.0 3.3 4 0 0 4 4 4 0 Septin AAA_19 PF13245.6 OQS00298.1 - 0.13 12.6 0.1 20 5.5 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.14 OQS00298.1 - 0.13 12.2 0.0 4 7.4 0.0 3.0 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) cobW PF02492.19 OQS00298.1 - 0.15 11.7 0.2 13 5.3 0.0 2.6 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Dynamin_N PF00350.23 OQS00298.1 - 0.2 11.7 0.4 1.3 9.1 0.0 2.4 2 0 0 2 2 2 0 Dynamin family AAA_23 PF13476.6 OQS00298.1 - 0.21 12.0 12.6 1.5 9.3 0.0 3.5 3 0 0 3 3 2 0 AAA domain PH_11 PF15413.6 OQS00298.1 - 0.24 11.8 3.2 0.55 10.7 3.2 1.6 1 0 0 1 1 1 0 Pleckstrin homology domain HEAT PF02985.22 OQS00298.1 - 0.89 10.0 3.4 62 4.3 0.0 4.9 5 0 0 5 5 4 0 HEAT repeat DUF3347 PF11827.8 OQS00298.1 - 2.9 8.1 6.2 5.9 7.0 6.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3347) Clat_adaptor_s PF01217.20 OQS00299.1 - 1.2e-50 171.1 0.2 1.3e-50 171.0 0.2 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Glyco_hydro_5_C PF18564.1 OQS00300.1 - 7.7e-14 52.0 0.1 1.5e-13 51.0 0.1 1.5 1 0 0 1 1 1 1 Glycoside hydrolase family 5 C-terminal domain Cellulase PF00150.18 OQS00300.1 - 1.8e-09 37.4 0.0 7.5e-07 28.9 0.0 2.7 2 2 0 2 2 2 2 Cellulase (glycosyl hydrolase family 5) Pkinase PF00069.25 OQS00302.1 - 6.5e-52 176.5 0.0 1e-51 175.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQS00302.1 - 3.3e-49 167.5 0.0 4.5e-49 167.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PH PF00169.29 OQS00302.1 - 6.4e-08 33.1 0.0 1.4e-07 31.9 0.0 1.6 1 0 0 1 1 1 1 PH domain SAM_1 PF00536.30 OQS00302.1 - 1.5e-06 28.6 0.1 6.9e-06 26.4 0.0 2.1 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) Pkinase_fungal PF17667.1 OQS00302.1 - 1.8e-06 27.0 0.0 3e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase SAM_2 PF07647.17 OQS00302.1 - 2.5e-05 24.3 0.1 7.8e-05 22.7 0.0 1.9 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) APH PF01636.23 OQS00302.1 - 0.00023 21.2 0.0 0.00056 19.9 0.0 1.6 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 OQS00302.1 - 0.0014 18.0 0.0 0.0025 17.2 0.0 1.4 1 0 0 1 1 1 1 Kinase-like PH_9 PF15410.6 OQS00302.1 - 0.018 15.4 0.5 0.098 13.0 0.5 2.0 1 1 0 1 1 1 0 Pleckstrin homology domain Kdo PF06293.14 OQS00302.1 - 0.024 14.0 0.1 0.047 13.0 0.1 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family gpW PF02831.15 OQS00302.1 - 0.096 12.6 0.0 0.23 11.4 0.0 1.6 1 0 0 1 1 1 0 gpW RIO1 PF01163.22 OQS00302.1 - 0.12 11.9 0.0 0.4 10.2 0.0 1.8 2 0 0 2 2 2 0 RIO1 family PH_8 PF15409.6 OQS00302.1 - 0.22 11.8 1.3 1.1 9.6 1.3 2.1 1 1 0 1 1 1 0 Pleckstrin homology domain Pyr_redox_2 PF07992.14 OQS00303.1 - 9e-25 87.5 0.0 9.1e-15 54.6 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Fer4_20 PF14691.6 OQS00303.1 - 6e-24 84.0 0.1 9.5e-24 83.4 0.1 1.3 1 0 0 1 1 1 1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster NAD_binding_8 PF13450.6 OQS00303.1 - 7.5e-10 38.9 0.0 6.8e-09 35.8 0.0 2.5 3 0 0 3 3 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 OQS00303.1 - 1.4e-08 34.4 0.0 0.004 16.5 0.0 3.4 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 OQS00303.1 - 2.2e-07 31.4 2.0 0.00029 21.3 0.4 3.5 3 1 0 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 OQS00303.1 - 1e-06 27.7 0.1 5.5e-05 22.1 0.3 2.2 2 0 0 2 2 2 1 HI0933-like protein Amino_oxidase PF01593.24 OQS00303.1 - 3.4e-06 26.6 0.3 9.8e-06 25.1 0.0 1.9 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase FAD_oxidored PF12831.7 OQS00303.1 - 3.7e-06 26.6 0.8 5.8e-06 25.9 0.0 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 OQS00303.1 - 4.3e-06 26.1 0.1 8e-05 21.9 0.0 2.6 3 0 0 3 3 3 1 FAD binding domain NAD_binding_7 PF13241.6 OQS00303.1 - 2.1e-05 24.9 0.0 0.24 11.8 0.0 2.5 2 0 0 2 2 2 2 Putative NAD(P)-binding GIDA PF01134.22 OQS00303.1 - 0.00015 21.0 0.0 0.0066 15.6 0.0 2.2 2 0 0 2 2 2 1 Glucose inhibited division protein A FAD_binding_3 PF01494.19 OQS00303.1 - 0.00021 20.6 0.8 0.00048 19.5 0.3 1.8 2 0 0 2 2 2 1 FAD binding domain AlaDh_PNT_C PF01262.21 OQS00303.1 - 0.00022 20.6 0.2 0.049 12.9 0.1 2.4 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain DAO PF01266.24 OQS00303.1 - 0.00025 20.7 2.2 0.013 15.1 0.3 2.9 1 1 2 3 3 3 1 FAD dependent oxidoreductase FMO-like PF00743.19 OQS00303.1 - 0.0018 16.8 0.1 1.4 7.2 0.0 2.4 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like 2-Hacid_dh_C PF02826.19 OQS00303.1 - 0.0026 17.1 0.1 0.3 10.4 0.0 2.6 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.23 OQS00303.1 - 0.0048 16.9 0.0 0.097 12.6 0.0 2.3 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Thi4 PF01946.17 OQS00303.1 - 0.0096 15.2 0.2 0.049 12.9 0.1 1.9 2 0 0 2 2 2 1 Thi4 family AdoHcyase_NAD PF00670.21 OQS00303.1 - 0.016 15.3 0.7 0.42 10.7 0.0 2.5 3 0 0 3 3 3 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain NAD_binding_9 PF13454.6 OQS00303.1 - 0.017 15.1 1.3 0.36 10.8 0.0 3.1 3 1 1 4 4 4 0 FAD-NAD(P)-binding TrkA_N PF02254.18 OQS00303.1 - 0.021 15.1 0.0 2.5 8.4 0.0 2.5 2 0 0 2 2 2 0 TrkA-N domain Shikimate_DH PF01488.20 OQS00303.1 - 0.022 14.8 0.1 3.3 7.8 0.0 3.0 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase YjeF_N PF03853.15 OQS00303.1 - 0.051 13.4 0.2 2.9 7.8 0.0 2.4 2 0 0 2 2 2 0 YjeF-related protein N-terminus Lycopene_cycl PF05834.12 OQS00303.1 - 0.062 12.3 0.2 0.36 9.8 0.3 2.0 2 0 0 2 2 2 0 Lycopene cyclase protein K_oxygenase PF13434.6 OQS00303.1 - 0.14 11.3 0.0 4.3 6.4 0.0 2.7 3 0 0 3 3 3 0 L-lysine 6-monooxygenase (NADPH-requiring) LRR_4 PF12799.7 OQS00304.1 - 1.1e-27 95.6 48.9 0.00058 20.2 0.3 11.8 7 3 5 12 12 12 10 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 OQS00304.1 - 7.2e-05 22.5 70.2 2.1 8.6 0.1 18.2 18 2 2 20 20 20 3 Leucine Rich repeat Coatomer_g_Cpla PF16381.5 OQS00304.1 - 0.00067 19.8 5.3 1.4 9.1 0.0 4.7 2 2 3 5 5 5 2 Coatomer subunit gamma-1 C-terminal appendage platform Chlam_OMP3 PF03503.13 OQS00304.1 - 0.046 14.0 1.8 5.2 7.5 0.1 4.4 3 0 0 3 3 3 0 Chlamydia cysteine-rich outer membrane protein 3 LRR_5 PF13306.6 OQS00304.1 - 0.051 13.5 8.1 6.4 6.8 1.2 5.0 3 2 1 4 4 4 0 BspA type Leucine rich repeat region (6 copies) LRR_1 PF00560.33 OQS00304.1 - 0.55 11.0 60.9 15 6.6 0.3 17.2 14 5 0 14 14 14 0 Leucine Rich Repeat LRR_6 PF13516.6 OQS00305.1 - 5.8e-09 35.3 14.3 0.00044 20.1 0.2 6.7 8 0 0 8 8 8 3 Leucine Rich repeat LRR_4 PF12799.7 OQS00305.1 - 0.00019 21.7 22.7 0.0009 19.6 0.0 6.6 6 2 1 8 8 8 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 OQS00305.1 - 0.0012 18.6 0.0 0.0012 18.6 0.0 6.1 8 0 0 8 8 8 1 Leucine rich repeat DUF1664 PF07889.12 OQS00306.1 - 0.02 14.9 0.5 0.02 14.9 0.5 4.8 3 1 1 4 4 4 0 Protein of unknown function (DUF1664) FdhD-NarQ PF02634.15 OQS00306.1 - 0.069 12.8 4.6 1.2 8.8 1.6 2.5 2 0 0 2 2 2 0 FdhD/NarQ family TRAF_BIRC3_bd PF16673.5 OQS00306.1 - 4.9 7.0 10.0 0.14 11.9 1.2 3.1 3 0 0 3 3 3 0 TNF receptor-associated factor BIRC3 binding domain FliD_C PF07195.12 OQS00306.1 - 4.9 6.5 9.2 0.29 10.5 1.0 2.6 2 1 0 2 2 2 0 Flagellar hook-associated protein 2 C-terminus DUF1319 PF07028.11 OQS00306.1 - 5.3 7.3 7.9 0.75 10.0 0.4 3.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1319) GCIP PF13324.6 OQS00307.1 - 1.4e-21 77.3 0.5 2e-21 76.8 0.5 1.2 1 0 0 1 1 1 1 Grap2 and cyclin-D-interacting DUF4715 PF15835.5 OQS00307.1 - 0.045 13.8 0.1 0.088 12.9 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4715) DEAD PF00270.29 OQS00308.1 - 6.9e-45 152.9 0.1 1.2e-44 152.1 0.1 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OQS00308.1 - 3.7e-31 107.7 0.2 1.7e-30 105.6 0.1 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain PCO_ADO PF07847.12 OQS00308.1 - 1e-27 96.9 0.3 2e-27 95.9 0.1 1.5 2 0 0 2 2 2 1 PCO_ADO Hydrolase_4 PF12146.8 OQS00308.1 - 1.5e-10 40.7 0.9 3.2e-07 29.9 0.7 2.3 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 OQS00308.1 - 6.4e-08 33.5 1.6 1.7e-07 32.1 1.0 2.0 2 1 0 2 2 2 1 Alpha/beta hydrolase family ResIII PF04851.15 OQS00308.1 - 3.4e-05 23.9 0.0 6.2e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Abhydrolase_1 PF00561.20 OQS00308.1 - 0.0004 20.1 1.2 0.0055 16.4 1.1 2.2 1 1 1 2 2 2 1 alpha/beta hydrolase fold AAA_30 PF13604.6 OQS00308.1 - 0.0007 19.4 0.0 0.0012 18.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain Peptidase_S9 PF00326.21 OQS00308.1 - 0.00078 19.0 0.0 0.0014 18.1 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_3 PF07859.13 OQS00308.1 - 0.0013 18.7 0.0 0.0024 17.7 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_2 PF02230.16 OQS00308.1 - 0.0018 18.2 0.4 0.17 11.7 0.0 2.7 3 0 0 3 3 3 1 Phospholipase/Carboxylesterase FSH1 PF03959.13 OQS00308.1 - 0.01 15.5 0.0 0.022 14.4 0.0 1.4 1 0 0 1 1 1 0 Serine hydrolase (FSH1) CMS1 PF14617.6 OQS00308.1 - 0.015 14.7 0.0 0.032 13.6 0.0 1.5 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit Helicase_RecD PF05127.14 OQS00308.1 - 0.13 12.1 0.1 0.56 10.0 0.1 1.9 2 0 0 2 2 2 0 Helicase PNP_UDP_1 PF01048.20 OQS00309.1 - 8.7e-23 80.8 0.0 1.1e-22 80.4 0.0 1.1 1 0 0 1 1 1 1 Phosphorylase superfamily TssN PF17555.2 OQS00310.1 - 0.056 12.8 7.9 0.07 12.5 6.8 1.7 1 1 0 1 1 1 0 Type VI secretion system, TssN GPR_Gpa2_C PF11970.8 OQS00310.1 - 0.79 9.8 3.6 21 5.3 0.2 2.8 2 0 0 2 2 2 0 G protein-coupled glucose receptor regulating Gpa2 C-term KIAA1430 PF13879.6 OQS00311.1 - 5e-19 68.9 1.5 5e-19 68.9 1.5 2.2 2 0 0 2 2 2 1 KIAA1430 homologue Erg28 PF03694.13 OQS00312.1 - 1e-09 38.7 0.0 1.4e-09 38.3 0.0 1.2 1 0 0 1 1 1 1 Erg28 like protein GPI-anchored PF10342.9 OQS00313.1 - 2.6e-05 24.9 0.0 3.3e-05 24.5 0.0 1.1 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Tudor_4 PF18358.1 OQS00313.1 - 0.023 14.3 0.0 0.04 13.5 0.0 1.3 1 0 0 1 1 1 0 Histone methyltransferase Tudor domain Voltage_CLC PF00654.20 OQS00314.1 - 4.4e-71 240.0 32.6 2.6e-70 237.5 27.1 2.1 1 1 1 2 2 2 2 Voltage gated chloride channel RE_R_Pab1 PF09522.10 OQS00314.1 - 0.083 13.0 0.0 0.24 11.5 0.0 1.8 1 0 0 1 1 1 0 R.Pab1 restriction endonuclease DUF5367 PF17329.2 OQS00314.1 - 2.4 8.3 6.8 0.6 10.3 2.3 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5367) PHF5 PF03660.14 OQS00315.1 - 8.2e-51 170.6 10.4 9.1e-51 170.4 10.4 1.0 1 0 0 1 1 1 1 PHF5-like protein PolC_DP2 PF03833.13 OQS00315.1 - 0.016 13.1 5.9 0.017 13.0 5.9 1.0 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 C1_2 PF03107.16 OQS00315.1 - 0.23 11.8 13.9 0.41 11.0 2.6 2.4 1 1 1 2 2 2 0 C1 domain zf-RanBP PF00641.18 OQS00315.1 - 0.3 10.4 3.7 12 5.3 0.0 3.2 3 0 0 3 3 3 0 Zn-finger in Ran binding protein and others DZR PF12773.7 OQS00315.1 - 0.51 10.4 12.1 4.3 7.4 2.1 2.4 1 1 1 2 2 2 0 Double zinc ribbon PHD PF00628.29 OQS00315.1 - 0.64 10.0 10.4 0.68 9.9 8.5 2.2 2 1 0 2 2 2 0 PHD-finger RecR PF02132.15 OQS00315.1 - 4.3 7.0 12.5 0.83 9.3 0.4 3.1 3 0 0 3 3 3 0 RecR protein COX17 PF05051.13 OQS00316.1 - 3.5e-19 68.9 5.4 4.1e-19 68.7 5.4 1.1 1 0 0 1 1 1 1 Cytochrome C oxidase copper chaperone (COX17) Methyltransf_11 PF08241.12 OQS00317.1 - 2.3e-10 41.0 0.0 1e-09 38.9 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OQS00317.1 - 2.4e-08 34.6 0.5 2.2e-06 28.3 0.1 3.0 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 OQS00317.1 - 3.2e-07 30.3 0.0 7e-07 29.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OQS00317.1 - 0.018 14.9 0.1 0.045 13.6 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_12 PF08242.12 OQS00317.1 - 0.028 15.2 0.0 0.34 11.7 0.0 2.4 1 1 0 1 1 1 0 Methyltransferase domain SMP_2 PF10144.9 OQS00317.1 - 0.072 12.7 0.1 0.13 11.9 0.1 1.4 1 0 0 1 1 1 0 Bacterial virulence factor haemolysin Pkinase PF00069.25 OQS00319.1 - 1e-55 189.0 1.1 1.7e-55 188.3 0.0 1.9 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQS00319.1 - 2.2e-25 89.4 0.0 5.4e-25 88.2 0.0 1.7 1 0 0 1 1 1 1 Protein tyrosine kinase Efg1 PF10153.9 OQS00319.1 - 2.5e-25 89.1 13.7 2.5e-25 89.1 13.7 4.1 4 1 0 4 4 4 1 rRNA-processing protein Efg1 Kdo PF06293.14 OQS00319.1 - 9.2e-07 28.4 1.9 2.2e-06 27.2 0.2 2.5 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 OQS00319.1 - 0.00016 21.3 0.2 0.00016 21.3 0.2 2.9 2 0 0 2 2 2 1 RIO1 family APH PF01636.23 OQS00319.1 - 0.00046 20.2 1.4 0.015 15.2 1.2 2.8 1 1 1 2 2 2 2 Phosphotransferase enzyme family HMG_box PF00505.19 OQS00320.1 - 8.3e-40 135.1 17.5 1e-21 77.1 6.7 2.4 2 0 0 2 2 2 2 HMG (high mobility group) box HMG_box_2 PF09011.10 OQS00320.1 - 6.5e-27 93.9 16.1 3.7e-13 49.9 1.9 2.5 2 0 0 2 2 2 2 HMG-box domain E1-E2_ATPase PF00122.20 OQS00320.1 - 6.9e-19 68.1 0.0 1.2e-18 67.2 0.0 1.4 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_N PF00690.26 OQS00320.1 - 0.0044 16.7 0.0 0.0099 15.6 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus HMG_box_5 PF14887.6 OQS00320.1 - 0.0048 16.8 17.7 0.077 13.0 2.8 3.0 2 1 1 3 3 3 2 HMG (high mobility group) box 5 Ccdc124 PF06244.12 OQS00320.1 - 0.01 16.4 0.8 0.01 16.4 0.8 3.1 1 1 1 3 3 3 0 Coiled-coil domain-containing protein 124 /Oxs1 DUF179 PF02622.15 OQS00321.1 - 2.1e-24 86.3 0.0 2.8e-24 85.9 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized ACR, COG1678 Holin_9 PF16936.5 OQS00323.1 - 0.033 14.4 1.4 0.041 14.0 1.4 1.2 1 0 0 1 1 1 0 Putative holin Peptidase_M17 PF00883.21 OQS00324.1 - 1.4e-99 333.3 0.6 2.3e-99 332.6 0.6 1.3 1 0 0 1 1 1 1 Cytosol aminopeptidase family, catalytic domain Pdase_M17_N2 PF18295.1 OQS00324.1 - 1.8e-21 76.7 0.3 6.4e-21 74.9 0.3 2.0 1 1 0 1 1 1 1 M17 aminopeptidase N-terminal domain 2 Kinesin PF00225.23 OQS00325.1 - 1.7e-105 352.6 3.3 2.4e-105 352.2 3.3 1.2 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 OQS00325.1 - 4.6e-17 62.3 0.1 2.8e-15 56.5 0.1 2.6 1 1 0 1 1 1 1 Microtubule binding ATG16 PF08614.11 OQS00325.1 - 0.00011 22.5 8.2 0.00011 22.5 8.2 2.0 2 0 0 2 2 2 1 Autophagy protein 16 (ATG16) ZapB PF06005.12 OQS00325.1 - 0.00086 19.7 8.5 0.0048 17.3 1.4 2.8 2 0 0 2 2 2 1 Cell division protein ZapB Ribosomal_L29 PF00831.23 OQS00325.1 - 0.00095 19.1 5.6 0.011 15.7 0.3 2.5 2 0 0 2 2 2 1 Ribosomal L29 protein bZIP_1 PF00170.21 OQS00325.1 - 0.001 19.2 6.1 0.26 11.4 0.9 2.6 2 0 0 2 2 2 2 bZIP transcription factor DUF4686 PF15742.5 OQS00325.1 - 0.002 17.3 9.2 0.0047 16.1 9.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4686) DivIC PF04977.15 OQS00325.1 - 0.017 14.9 7.1 0.17 11.7 0.5 2.7 2 0 0 2 2 2 0 Septum formation initiator Spc7 PF08317.11 OQS00325.1 - 0.046 12.6 7.9 0.087 11.7 6.9 1.8 2 0 0 2 2 2 0 Spc7 kinetochore protein DUF4600 PF15372.6 OQS00325.1 - 0.053 14.0 5.5 0.15 12.5 5.5 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4600) HALZ PF02183.18 OQS00325.1 - 0.057 13.6 9.7 1.4 9.2 0.7 2.6 2 0 0 2 2 2 0 Homeobox associated leucine zipper SlyX PF04102.12 OQS00325.1 - 0.058 14.0 0.7 0.058 14.0 0.7 2.4 2 0 0 2 2 2 0 SlyX Cnn_1N PF07989.11 OQS00325.1 - 0.077 13.2 6.8 0.71 10.1 0.9 2.7 2 0 0 2 2 2 0 Centrosomin N-terminal motif 1 TMF_TATA_bd PF12325.8 OQS00325.1 - 0.15 12.3 10.4 2.5 8.3 4.0 2.7 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding JIP_LZII PF16471.5 OQS00325.1 - 0.18 12.0 6.5 2.7 8.2 0.4 2.7 2 0 0 2 2 2 0 JNK-interacting protein leucine zipper II bZIP_2 PF07716.15 OQS00325.1 - 0.18 11.9 11.3 1.1 9.4 3.0 2.9 2 0 0 2 2 2 0 Basic region leucine zipper Med21 PF11221.8 OQS00325.1 - 0.18 12.0 3.8 5.7 7.2 0.1 2.8 2 0 0 2 2 2 0 Subunit 21 of Mediator complex FlaC_arch PF05377.11 OQS00325.1 - 0.2 12.1 4.3 4 7.9 0.3 2.9 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) FlxA PF14282.6 OQS00325.1 - 0.27 11.2 3.0 4.1 7.4 0.4 3.1 2 0 0 2 2 2 0 FlxA-like protein TSC22 PF01166.18 OQS00325.1 - 0.33 11.3 6.6 1.3 9.4 0.5 2.9 3 0 0 3 3 2 0 TSC-22/dip/bun family Csm1_N PF18504.1 OQS00325.1 - 0.34 11.3 5.5 10 6.6 0.4 2.6 2 0 0 2 2 2 0 Csm1 N-terminal domain NYD-SP28_assoc PF14775.6 OQS00325.1 - 0.39 10.8 5.2 3.5 7.8 0.4 3.0 3 0 0 3 3 2 0 Sperm tail C-terminal domain Shugoshin_N PF07558.11 OQS00325.1 - 0.41 10.6 8.8 4.2 7.3 0.3 3.5 3 0 0 3 3 3 0 Shugoshin N-terminal coiled-coil region DUF4337 PF14235.6 OQS00325.1 - 0.41 10.8 6.8 0.11 12.6 1.1 2.4 2 1 1 3 3 2 0 Domain of unknown function (DUF4337) GIT_CC PF16559.5 OQS00325.1 - 0.46 10.4 5.7 5.4 7.0 0.6 2.9 3 0 0 3 3 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor Ax_dynein_light PF10211.9 OQS00325.1 - 0.48 10.3 12.0 1.6 8.6 2.8 2.6 1 1 1 2 2 2 0 Axonemal dynein light chain Spc24 PF08286.11 OQS00325.1 - 0.52 10.6 7.4 2.5 8.4 0.2 3.1 3 0 0 3 3 3 0 Spc24 subunit of Ndc80 APG6_N PF17675.1 OQS00325.1 - 0.74 10.3 14.8 3.4 8.2 3.0 3.1 2 1 1 3 3 3 0 Apg6 coiled-coil region UPF0242 PF06785.11 OQS00325.1 - 0.9 9.6 5.4 2.1 8.4 5.4 1.6 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus SOGA PF11365.8 OQS00325.1 - 0.97 10.6 8.3 2.8 9.1 1.6 2.8 1 1 1 2 2 2 0 Protein SOGA K-box PF01486.17 OQS00325.1 - 0.98 9.6 8.8 6.1 7.1 0.6 2.7 1 1 1 2 2 2 0 K-box region TMF_DNA_bd PF12329.8 OQS00325.1 - 1.2 9.2 13.2 0.6 10.1 1.4 3.4 3 0 0 3 3 3 0 TATA element modulatory factor 1 DNA binding Swi5 PF07061.11 OQS00325.1 - 1.7 8.8 5.6 9.2 6.4 0.2 2.9 3 0 0 3 3 2 0 Swi5 Jnk-SapK_ap_N PF09744.9 OQS00325.1 - 2.4 8.4 14.5 1.6 8.9 11.3 2.3 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 FapA PF03961.13 OQS00325.1 - 3.7 6.0 9.5 7.2 5.1 9.1 1.6 1 1 0 1 1 1 0 Flagellar Assembly Protein A DUF4482 PF14818.6 OQS00325.1 - 4.8 8.1 12.9 0.24 12.3 1.4 3.3 1 1 3 4 4 3 0 Domain of unknown function (DUF4482) CCDC-167 PF15188.6 OQS00325.1 - 6.6 7.1 12.1 46 4.5 11.9 2.4 1 1 0 1 1 1 0 Coiled-coil domain-containing protein 167 DUF2013 PF09431.10 OQS00326.1 - 9.8e-06 25.8 0.0 1.5e-05 25.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2013) Myb_DNA-bind_5 PF13873.6 OQS00326.1 - 0.037 14.1 0.1 0.087 12.9 0.1 1.6 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain Nop25 PF09805.9 OQS00328.1 - 5.7e-13 49.5 16.7 5.7e-13 49.5 16.7 1.8 1 1 0 1 1 1 1 Nucleolar protein 12 (25kDa) CDT1_C PF16679.5 OQS00328.1 - 0.22 12.0 5.7 1.3 9.5 0.3 2.6 2 1 0 2 2 2 0 DNA replication factor Cdt1 C-terminal domain DUF2508 PF10704.9 OQS00328.1 - 1.1 9.5 10.7 5.9 7.1 1.7 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2508) Fringe PF02434.16 OQS00329.1 - 1.9e-10 40.6 0.2 4.4e-10 39.4 0.2 1.5 1 1 0 1 1 1 1 Fringe-like Sec63 PF02889.16 OQS00330.1 - 1.7e-99 332.1 0.6 2.2e-80 269.6 0.1 2.9 3 0 0 3 3 3 2 Sec63 Brl domain DEAD PF00270.29 OQS00330.1 - 3.7e-41 140.8 0.0 4.9e-26 91.6 0.3 2.7 2 0 0 2 2 2 2 DEAD/DEAH box helicase Helicase_PWI PF18149.1 OQS00330.1 - 2.4e-38 130.7 1.9 1.2e-37 128.5 0.3 3.0 3 0 0 3 3 3 1 N-terminal helicase PWI domain ResIII PF04851.15 OQS00330.1 - 8.2e-16 58.5 0.3 5.4e-13 49.3 0.0 3.3 4 0 0 4 4 4 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 OQS00330.1 - 1e-09 38.7 0.0 2.1e-07 31.3 0.0 3.5 2 2 0 2 2 2 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 OQS00330.1 - 1.8e-09 38.0 0.0 0.0027 18.0 0.1 3.0 2 0 0 2 2 2 2 AAA domain DUF603 PF04645.12 OQS00330.1 - 0.00037 20.2 0.2 0.00088 19.0 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function, DUF603 AAA_19 PF13245.6 OQS00330.1 - 0.00076 19.8 0.0 0.49 10.7 0.2 2.8 2 0 0 2 2 2 1 AAA domain UvrD-helicase PF00580.21 OQS00330.1 - 0.0065 16.0 0.2 2.2 7.7 0.0 3.2 3 0 0 3 3 3 1 UvrD/REP helicase N-terminal domain IstB_IS21 PF01695.17 OQS00330.1 - 0.0093 15.7 0.0 3.1 7.5 0.0 2.6 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_7 PF12775.7 OQS00330.1 - 0.069 12.7 0.0 15 5.0 0.0 2.5 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_11 PF13086.6 OQS00330.1 - 0.071 12.9 1.3 0.96 9.2 0.0 3.1 3 0 0 3 3 3 0 AAA domain WaaY PF06176.11 OQS00331.1 - 0.066 12.8 2.3 0.39 10.3 0.0 2.7 3 0 0 3 3 3 0 Lipopolysaccharide core biosynthesis protein (WaaY) AAA_12 PF13087.6 OQS00332.1 - 4.5e-41 140.7 0.0 1.5e-40 139.0 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.6 OQS00332.1 - 6.4e-26 91.7 0.0 3.8e-14 53.1 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.6 OQS00332.1 - 6.1e-10 39.6 0.0 3.5e-09 37.2 0.0 2.3 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 OQS00332.1 - 6.8e-10 39.0 0.0 1.8e-09 37.6 0.0 1.7 1 1 0 1 1 1 1 AAA domain UvrD-helicase PF00580.21 OQS00332.1 - 2.3e-07 30.7 0.0 2.4e-05 24.0 0.0 2.4 2 0 0 2 2 2 1 UvrD/REP helicase N-terminal domain ResIII PF04851.15 OQS00332.1 - 2.8e-05 24.2 0.0 6.7e-05 23.0 0.0 1.7 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 OQS00332.1 - 0.00036 20.3 0.0 0.0054 16.5 0.0 2.7 3 0 0 3 3 3 1 DEAD/DEAH box helicase Viral_helicase1 PF01443.18 OQS00332.1 - 0.00058 19.7 0.1 0.6 9.8 0.0 3.4 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase PhoH PF02562.16 OQS00332.1 - 0.0014 18.1 0.0 0.17 11.3 0.0 2.4 2 0 0 2 2 2 1 PhoH-like protein Y_phosphatase PF00102.27 OQS00332.1 - 0.0034 17.0 0.1 0.074 12.6 0.0 2.2 2 0 0 2 2 2 1 Protein-tyrosine phosphatase AAA_22 PF13401.6 OQS00332.1 - 0.031 14.6 0.0 0.099 12.9 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 OQS00332.1 - 0.034 14.5 0.0 0.086 13.2 0.0 1.7 2 0 0 2 2 1 0 AAA ATPase domain AAA_7 PF12775.7 OQS00332.1 - 0.04 13.4 0.0 0.088 12.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region UvrD_C_2 PF13538.6 OQS00332.1 - 0.051 13.4 0.2 0.27 11.1 0.2 2.1 1 1 0 1 1 1 0 UvrD-like helicase C-terminal domain T2SSE PF00437.20 OQS00332.1 - 0.052 12.6 0.0 0.096 11.7 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein DUF2075 PF09848.9 OQS00332.1 - 0.061 12.5 0.0 0.13 11.4 0.0 1.6 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA PF00004.29 OQS00332.1 - 0.065 13.7 0.0 0.15 12.5 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.21 OQS00332.1 - 0.1 12.0 0.0 0.24 10.8 0.0 1.6 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI DUF5600 PF18150.1 OQS00333.1 - 1.5e-39 134.8 2.2 3.3e-39 133.7 2.2 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF5600) EHD_N PF16880.5 OQS00333.1 - 2.6e-16 59.2 2.3 4.6e-16 58.4 2.3 1.4 1 0 0 1 1 1 1 N-terminal EH-domain containing protein Dynamin_N PF00350.23 OQS00333.1 - 2.6e-15 56.9 0.0 2.4e-07 30.9 0.0 2.4 2 0 0 2 2 2 2 Dynamin family EF-hand_4 PF12763.7 OQS00333.1 - 3.1e-10 39.9 0.0 3.5e-09 36.6 0.0 2.6 3 0 0 3 3 3 1 Cytoskeletal-regulatory complex EF hand MMR_HSR1 PF01926.23 OQS00333.1 - 4.1e-10 39.8 0.0 1.1e-09 38.4 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase EF-hand_1 PF00036.32 OQS00333.1 - 1.3e-05 24.4 0.3 6.5e-05 22.2 0.3 2.3 1 0 0 1 1 1 1 EF hand Gtr1_RagA PF04670.12 OQS00333.1 - 0.00038 19.9 0.0 0.00093 18.6 0.0 1.6 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region Roc PF08477.13 OQS00333.1 - 0.00075 19.7 0.0 0.34 11.2 0.0 2.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase GTP_EFTU PF00009.27 OQS00333.1 - 0.0024 17.4 0.0 0.014 14.9 0.0 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain EF-hand_7 PF13499.6 OQS00333.1 - 0.0046 17.4 0.2 0.051 14.0 0.1 2.6 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 OQS00333.1 - 0.0058 16.5 0.6 0.042 13.8 0.3 2.6 2 0 0 2 2 2 1 EF-hand domain FeoB_N PF02421.18 OQS00333.1 - 0.0076 15.8 0.0 1.2 8.6 0.0 2.3 2 0 0 2 2 2 1 Ferrous iron transport protein B AIG1 PF04548.16 OQS00333.1 - 0.009 15.4 0.0 0.088 12.1 0.0 2.2 2 0 0 2 2 2 1 AIG1 family EF-hand_5 PF13202.6 OQS00333.1 - 0.013 15.0 0.2 0.054 13.0 0.2 2.1 1 0 0 1 1 1 0 EF hand Ras PF00071.22 OQS00333.1 - 0.042 13.5 0.4 8.1 6.0 0.0 2.9 3 0 0 3 3 3 0 Ras family RsgA_GTPase PF03193.16 OQS00333.1 - 0.06 13.3 0.0 9.7 6.1 0.0 3.1 3 0 0 3 3 3 0 RsgA GTPase Longin PF13774.6 OQS00334.1 - 3.8e-13 49.3 0.0 1.5e-12 47.3 0.0 1.9 2 0 0 2 2 2 1 Regulated-SNARE-like domain Synaptobrevin PF00957.21 OQS00334.1 - 8.1e-11 41.6 0.0 1.5e-10 40.7 0.0 1.4 1 0 0 1 1 1 1 Synaptobrevin Pr_beta_C PF12465.8 OQS00334.1 - 0.44 10.0 1.7 0.62 9.5 0.2 2.0 2 0 0 2 2 2 0 Proteasome beta subunits C terminal COPI_assoc PF08507.10 OQS00335.1 - 4.3e-20 72.1 10.8 5.6e-20 71.7 10.8 1.1 1 0 0 1 1 1 1 COPI associated protein DUF4231 PF14015.6 OQS00335.1 - 0.013 16.0 0.1 0.028 14.9 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4231) NiFe_hyd_3_EhaA PF17367.2 OQS00335.1 - 0.023 14.8 0.9 0.023 14.8 0.9 2.4 2 1 1 3 3 3 0 NiFe-hydrogenase-type-3 Eha complex subunit A DUF3784 PF12650.7 OQS00335.1 - 0.028 14.6 7.2 0.18 12.0 1.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3784) SCAMP PF04144.13 OQS00335.1 - 0.11 12.8 10.6 0.76 10.1 11.0 1.8 1 1 1 2 2 2 0 SCAMP family DHHC PF01529.20 OQS00335.1 - 3.2 7.9 7.6 2 8.5 5.3 1.7 1 1 1 2 2 2 0 DHHC palmitoyltransferase Peptidase_C48 PF02902.19 OQS00336.1 - 9.6e-40 136.7 1.4 2.1e-39 135.6 1.4 1.5 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Inj_translocase PF16928.5 OQS00336.1 - 0.0028 17.1 0.1 0.0045 16.5 0.1 1.2 1 0 0 1 1 1 1 DNA/protein translocase of phage P22 injectosome DUF2070 PF09843.9 OQS00337.1 - 5.3e-05 21.7 1.6 8.2e-05 21.1 1.6 1.2 1 0 0 1 1 1 1 Predicted membrane protein (DUF2070) DUF2852 PF11014.8 OQS00337.1 - 0.047 13.9 1.2 3.9 7.7 0.1 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2852) DUF4293 PF14126.6 OQS00337.1 - 0.12 12.6 8.8 0.19 12.0 5.1 2.5 1 1 2 3 3 3 0 Domain of unknown function (DUF4293) DUF3810 PF12725.7 OQS00337.1 - 1.2 8.4 12.4 0.23 10.8 1.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3810) DUF996 PF06195.13 OQS00337.1 - 3.9 7.8 15.0 0.38 11.0 5.8 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF996) ABC2_membrane_5 PF13346.6 OQS00337.1 - 4.6 6.7 15.4 24 4.4 15.7 2.0 1 1 0 1 1 1 0 ABC-2 family transporter protein DUF3671 PF12420.8 OQS00337.1 - 7.3 6.7 8.3 1.1e+02 2.9 8.3 2.6 1 1 0 1 1 1 0 Protein of unknown function Stealth_CR2 PF11380.8 OQS00338.1 - 2.2e-88 291.6 0.3 1.2e-42 144.5 0.0 3.4 3 0 0 3 3 3 2 Stealth protein CR2, conserved region 2 Notch PF00066.17 OQS00338.1 - 3.1e-28 97.9 65.3 7.4e-08 32.7 8.6 4.7 4 0 0 4 4 4 4 LNR domain Stealth_CR1 PF17101.5 OQS00338.1 - 6.4e-23 80.2 12.4 1.1e-11 44.3 4.0 2.6 2 0 0 2 2 2 2 Stealth protein CR1, conserved region 1 Stealth_CR3 PF17102.5 OQS00338.1 - 4.9e-17 61.5 4.9 4.9e-17 61.5 4.9 2.4 3 0 0 3 3 3 1 Stealth protein CR3, conserved region 3 Stealth_CR4 PF17103.5 OQS00338.1 - 2.1e-13 49.9 0.1 4.6e-13 48.8 0.1 1.5 1 0 0 1 1 1 1 Stealth protein CR4, conserved region 4 PH PF00169.29 OQS00339.1 - 8.4e-12 45.5 0.5 4.8e-06 27.0 0.2 2.9 2 1 0 2 2 2 2 PH domain PH_11 PF15413.6 OQS00339.1 - 3.7e-11 43.4 0.7 0.00012 22.4 0.1 2.4 2 0 0 2 2 2 2 Pleckstrin homology domain PH_8 PF15409.6 OQS00339.1 - 1.5e-06 28.4 0.1 0.012 15.8 0.1 2.3 2 0 0 2 2 2 2 Pleckstrin homology domain PH_3 PF14593.6 OQS00339.1 - 0.00012 22.1 0.0 0.45 10.6 0.0 2.2 2 0 0 2 2 2 2 PH domain PH_9 PF15410.6 OQS00339.1 - 0.0014 19.0 0.1 14 6.0 0.1 3.8 1 1 2 3 3 3 1 Pleckstrin homology domain RNase_Zc3h12a_2 PF14626.6 OQS00339.1 - 0.06 13.6 0.1 0.13 12.5 0.0 1.7 2 0 0 2 2 2 0 Zc3h12a-like Ribonuclease NYN domain COPIIcoated_ERV PF07970.12 OQS00340.1 - 3.2e-31 108.9 0.1 6.5e-31 107.9 0.1 1.5 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 OQS00340.1 - 3.9e-26 91.2 0.2 8.4e-26 90.2 0.2 1.6 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Thioredoxin PF00085.20 OQS00340.1 - 6.9e-22 77.4 0.0 1.5e-21 76.3 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 OQS00340.1 - 0.00065 20.1 0.1 0.0035 17.8 0.1 2.2 1 1 0 1 1 1 1 Thioredoxin-like domain CAP PF00188.26 OQS00341.1 - 1e-07 32.8 0.0 1.9e-07 32.0 0.0 1.5 1 1 0 1 1 1 1 Cysteine-rich secretory protein family WBS_methylT PF12589.8 OQS00342.1 - 0.04 14.7 0.3 0.062 14.1 0.3 1.3 1 0 0 1 1 1 0 Methyltransferase involved in Williams-Beuren syndrome Ran_BP1 PF00638.18 OQS00343.1 - 1.4e-07 31.8 0.0 5e-07 30.0 0.0 1.9 1 1 0 1 1 1 1 RanBP1 domain Chibby PF14645.6 OQS00344.1 - 7.9e-05 23.0 3.9 0.0002 21.7 3.9 1.7 1 1 0 1 1 1 1 Chibby family HALZ PF02183.18 OQS00344.1 - 0.0018 18.5 1.7 0.0018 18.5 1.7 1.9 2 1 0 2 2 2 1 Homeobox associated leucine zipper TSC22 PF01166.18 OQS00344.1 - 0.0025 18.1 1.9 0.0025 18.1 1.9 1.6 1 1 0 1 1 1 1 TSC-22/dip/bun family DUF2312 PF10073.9 OQS00344.1 - 0.0079 15.8 1.1 0.0092 15.6 1.1 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2312) HAP1_N PF04849.13 OQS00344.1 - 0.0082 15.4 6.1 0.0092 15.2 6.1 1.1 1 0 0 1 1 1 1 HAP1 N-terminal conserved region GIT1_C PF12205.8 OQS00344.1 - 0.049 13.8 1.5 0.054 13.6 1.5 1.2 1 0 0 1 1 1 0 G protein-coupled receptor kinase-interacting protein 1 C term bZIP_2 PF07716.15 OQS00344.1 - 0.091 12.9 7.1 0.081 13.0 4.4 2.0 2 0 0 2 2 2 0 Basic region leucine zipper DivIC PF04977.15 OQS00344.1 - 0.18 11.6 4.2 0.11 12.3 2.5 1.5 1 1 0 2 2 2 0 Septum formation initiator Pep_deformylase PF01327.21 OQS00345.1 - 5.4e-33 113.8 0.1 1e-31 109.7 0.0 2.9 3 0 0 3 3 3 1 Polypeptide deformylase Vps51 PF08700.11 OQS00345.1 - 1.6e-21 76.1 3.5 1.6e-21 76.1 3.5 3.1 3 0 0 3 3 3 1 Vps51/Vps67 Dor1 PF04124.12 OQS00345.1 - 6.2e-12 44.9 10.1 1.1e-11 44.0 5.5 2.5 2 0 0 2 2 2 1 Dor1-like family Sec5 PF15469.6 OQS00345.1 - 9.1e-12 45.2 6.9 2e-11 44.1 6.1 2.0 2 0 0 2 2 2 1 Exocyst complex component Sec5 COG5 PF10392.9 OQS00345.1 - 1.3e-05 25.3 0.2 7e-05 23.0 0.2 2.3 1 0 0 1 1 1 1 Golgi transport complex subunit 5 Zw10 PF06248.13 OQS00345.1 - 3.4e-05 22.6 7.6 6e-05 21.8 7.6 1.3 1 0 0 1 1 1 1 Centromere/kinetochore Zw10 COG2 PF06148.11 OQS00345.1 - 6.6e-05 23.0 2.5 0.00032 20.8 2.5 2.2 1 0 0 1 1 1 1 COG (conserved oligomeric Golgi) complex component, COG2 Vps54_N PF10475.9 OQS00345.1 - 0.00014 21.3 6.4 0.00014 21.3 6.4 2.7 3 0 0 3 3 3 1 Vacuolar-sorting protein 54, of GARP complex HIP1_clath_bdg PF16515.5 OQS00345.1 - 0.15 12.7 3.9 0.22 12.2 1.4 2.5 2 0 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 BORCS6 PF10157.9 OQS00345.1 - 2.2 8.5 5.9 1 9.6 2.1 2.5 3 0 0 3 3 3 0 BLOC-1-related complex sub-unit 6 Lactamase_B_2 PF12706.7 OQS00346.1 - 3.7e-09 36.4 0.7 2.1e-08 33.9 0.7 2.1 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 OQS00346.1 - 0.0025 17.9 0.8 0.0057 16.7 0.8 1.5 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Phyto_Pns9_10 PF05878.11 OQS00346.1 - 0.12 11.6 0.0 0.19 10.8 0.0 1.3 1 0 0 1 1 1 0 Phytoreovirus nonstructural protein Pns9/Pns10 Corazonin PF17308.2 OQS00348.1 - 0.14 12.5 1.1 2.2 8.7 0.2 2.0 1 1 1 2 2 2 0 Pro-corazonin SH3_1 PF00018.28 OQS00349.1 - 0.0085 15.7 1.0 0.034 13.7 0.1 2.3 3 0 0 3 3 3 1 SH3 domain TUDOR PF00567.24 OQS00349.1 - 0.0088 16.1 0.1 0.039 14.0 0.0 2.0 2 0 0 2 2 2 1 Tudor domain Agenet PF05641.12 OQS00349.1 - 0.017 15.6 1.8 0.042 14.3 1.8 1.7 1 0 0 1 1 1 0 Agenet domain Phage_prot_Gp6 PF05133.14 OQS00349.1 - 0.1 11.7 0.1 0.14 11.3 0.1 1.2 1 0 0 1 1 1 0 Phage portal protein, SPP1 Gp6-like Rhodanese PF00581.20 OQS00350.1 - 2.4e-23 82.7 0.0 9e-14 51.9 0.0 2.1 2 0 0 2 2 2 2 Rhodanese-like domain SOR_SNZ PF01680.17 OQS00351.1 - 2.6e-112 373.6 9.8 2.6e-112 373.6 9.8 1.6 2 0 0 2 2 2 1 SOR/SNZ family ThiG PF05690.14 OQS00351.1 - 2.7e-10 40.0 8.2 1.2e-08 34.6 0.6 2.8 2 1 1 3 3 3 2 Thiazole biosynthesis protein ThiG Dus PF01207.17 OQS00351.1 - 6.8e-06 25.4 0.2 0.052 12.6 0.0 2.5 2 1 0 2 2 2 2 Dihydrouridine synthase (Dus) His_biosynth PF00977.21 OQS00351.1 - 0.001 18.6 0.7 0.025 14.1 0.1 2.2 2 0 0 2 2 2 1 Histidine biosynthesis protein OMPdecase PF00215.24 OQS00351.1 - 0.0012 18.5 0.4 0.91 9.1 0.0 2.3 1 1 1 2 2 2 2 Orotidine 5'-phosphate decarboxylase / HUMPS family IMPDH PF00478.25 OQS00351.1 - 0.0033 16.5 1.9 0.0043 16.1 1.9 1.2 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain NanE PF04131.14 OQS00351.1 - 0.0066 15.6 1.5 0.039 13.1 0.1 2.5 2 1 0 2 2 2 1 Putative N-acetylmannosamine-6-phosphate epimerase TetR_C_27 PF17935.1 OQS00351.1 - 0.023 14.7 0.1 0.11 12.6 0.0 2.1 3 0 0 3 3 3 0 Tetracyclin repressor-like, C-terminal domain IGPS PF00218.21 OQS00351.1 - 0.024 13.8 0.2 0.6 9.2 0.0 2.5 2 1 0 2 2 2 0 Indole-3-glycerol phosphate synthase DUF561 PF04481.12 OQS00351.1 - 0.055 12.6 0.4 3.8 6.6 0.0 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF561) NMO PF03060.15 OQS00351.1 - 0.21 10.9 9.4 0.33 10.3 1.9 2.3 2 0 0 2 2 2 0 Nitronate monooxygenase CHD5 PF04420.14 OQS00352.1 - 1.3e-10 41.3 0.0 1.8e-10 40.9 0.0 1.2 1 0 0 1 1 1 1 CHD5-like protein Anophelin PF10731.9 OQS00352.1 - 0.044 13.6 0.0 0.088 12.7 0.0 1.5 1 0 0 1 1 1 0 Thrombin inhibitor from mosquito Paf67 PF10255.9 OQS00352.1 - 0.046 12.7 0.3 0.055 12.5 0.3 1.1 1 0 0 1 1 1 0 RNA polymerase I-associated factor PAF67 PRCH PF03967.13 OQS00352.1 - 0.072 13.3 0.1 0.098 12.9 0.1 1.2 1 0 0 1 1 1 0 Photosynthetic reaction centre, H-chain N-terminal region Scaffolding_pro PF11418.8 OQS00352.1 - 0.1 13.2 0.2 0.14 12.7 0.2 1.1 1 0 0 1 1 1 0 Phi29 scaffolding protein Apyrase PF06079.11 OQS00353.1 - 1.2e-14 54.3 0.0 1.5e-14 53.9 0.0 1.1 1 0 0 1 1 1 1 Apyrase GAT PF03127.14 OQS00354.1 - 0.034 14.5 0.9 0.76 10.1 0.1 2.4 2 0 0 2 2 2 0 GAT domain bZIP_Maf PF03131.17 OQS00354.1 - 0.092 13.3 3.3 0.16 12.5 3.3 1.3 1 0 0 1 1 1 0 bZIP Maf transcription factor DEAD PF00270.29 OQS00355.1 - 8e-43 146.2 0.0 2.2e-42 144.8 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OQS00355.1 - 1e-28 99.9 0.0 4.6e-28 97.8 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 OQS00355.1 - 0.00043 20.3 0.0 0.001 19.1 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit zf-CCHC PF00098.23 OQS00355.1 - 0.0032 17.5 1.6 0.0032 17.5 1.6 2.3 3 0 0 3 3 3 1 Zinc knuckle tRNA_anti-codon PF01336.25 OQS00356.1 - 9.2e-05 22.4 0.0 0.00022 21.1 0.0 1.6 1 1 0 1 1 1 1 OB-fold nucleic acid binding domain PAC1 PF16094.5 OQS00356.1 - 0.023 13.9 0.0 0.039 13.1 0.0 1.3 1 0 0 1 1 1 0 Proteasome assembly chaperone 4 RMI2 PF16100.5 OQS00356.1 - 0.028 14.2 0.1 0.049 13.4 0.1 1.5 1 0 0 1 1 1 0 RecQ-mediated genome instability protein 2 Stn1 PF10451.9 OQS00356.1 - 0.032 13.2 1.1 0.052 12.5 0.1 1.9 3 0 0 3 3 3 0 Telomere regulation protein Stn1 SUIM_assoc PF16619.5 OQS00359.1 - 0.0022 18.0 4.6 0.011 15.8 2.4 3.1 2 1 0 2 2 2 1 Unstructured region C-term to UIM in Ataxin3 LBR_tudor PF09465.10 OQS00359.1 - 0.018 14.8 0.1 0.036 13.9 0.1 1.4 1 0 0 1 1 1 0 Lamin-B receptor of TUDOR domain CAP_GLY PF01302.25 OQS00360.1 - 8.8e-18 64.1 0.2 1.4e-17 63.5 0.2 1.3 1 0 0 1 1 1 1 CAP-Gly domain Erg28 PF03694.13 OQS00360.1 - 0.022 15.2 0.3 3.5 8.0 0.0 2.9 2 1 1 3 3 3 0 Erg28 like protein MFS_1 PF07690.16 OQS00361.1 - 9.8e-37 126.7 31.9 9.8e-37 126.7 31.9 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 OQS00361.1 - 7.5e-08 31.7 18.3 0.00074 18.5 3.6 2.4 2 1 0 2 2 2 2 Sugar (and other) transporter DUF4149 PF13664.6 OQS00361.1 - 0.32 11.4 12.3 0.48 10.8 0.2 3.7 4 0 0 4 4 4 0 Domain of unknown function (DUF4149) OATP PF03137.20 OQS00361.1 - 0.41 8.9 14.5 0.014 13.7 1.8 2.7 3 1 0 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family Abhydrolase_6 PF12697.7 OQS00362.1 - 3.5e-30 106.2 0.3 4.3e-30 105.9 0.3 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 OQS00362.1 - 2.5e-15 56.9 0.0 4e-15 56.2 0.0 1.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 OQS00362.1 - 2.1e-13 50.1 0.0 3.6e-13 49.3 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_2 PF02230.16 OQS00362.1 - 5.4e-05 23.1 0.1 0.026 14.3 0.0 2.1 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase Chlorophyllase2 PF12740.7 OQS00362.1 - 0.00036 19.5 0.0 0.00053 19.0 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme Chlorophyllase PF07224.11 OQS00362.1 - 0.00049 19.2 0.0 0.00067 18.8 0.0 1.1 1 0 0 1 1 1 1 Chlorophyllase PGAP1 PF07819.13 OQS00362.1 - 0.00099 18.9 0.0 0.0014 18.4 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein Thioesterase PF00975.20 OQS00362.1 - 0.0015 18.7 0.0 0.0023 18.1 0.0 1.4 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_3 PF07859.13 OQS00362.1 - 0.0027 17.6 0.9 0.017 15.0 0.8 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.7 OQS00362.1 - 0.016 15.0 0.0 0.026 14.3 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Lipase_3 PF01764.25 OQS00362.1 - 0.025 14.4 0.0 0.051 13.5 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 3) LIDHydrolase PF10230.9 OQS00362.1 - 0.059 12.9 0.0 0.088 12.3 0.0 1.2 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase Esterase PF00756.20 OQS00362.1 - 0.066 12.8 0.1 0.13 11.8 0.1 1.5 1 1 0 1 1 1 0 Putative esterase DEAD PF00270.29 OQS00363.1 - 4.9e-19 68.8 0.0 1.1e-18 67.6 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OQS00363.1 - 1.7e-13 50.9 0.0 4.6e-13 49.5 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain RecQ_Zn_bind PF16124.5 OQS00363.1 - 2.5e-07 31.3 0.5 2.5e-07 31.3 0.5 2.3 2 0 0 2 2 2 1 RecQ zinc-binding ResIII PF04851.15 OQS00363.1 - 2.2e-05 24.6 0.1 5.5e-05 23.2 0.0 1.7 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 OQS00363.1 - 0.00028 21.2 0.5 0.012 15.8 0.0 3.1 2 1 1 3 3 3 1 AAA domain T4SS-DNA_transf PF02534.14 OQS00363.1 - 0.0011 17.9 0.3 0.015 14.1 0.0 2.3 3 0 0 3 3 3 1 Type IV secretory system Conjugative DNA transfer INTS5_N PF14837.6 OQS00363.1 - 0.0031 17.1 0.0 0.0078 15.8 0.0 1.6 1 0 0 1 1 1 1 Integrator complex subunit 5 N-terminus GIDA_assoc PF13932.6 OQS00363.1 - 0.0087 16.3 0.0 0.015 15.5 0.0 1.4 1 0 0 1 1 1 1 GidA associated domain SNF2_N PF00176.23 OQS00363.1 - 0.03 13.0 0.1 0.078 11.7 0.0 1.7 2 0 0 2 2 2 0 SNF2 family N-terminal domain DUF243 PF03103.17 OQS00363.1 - 0.063 13.6 3.1 0.15 12.4 0.1 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF243) Noelin-1 PF12308.8 OQS00363.1 - 0.17 11.9 1.0 0.58 10.2 1.0 2.0 1 0 0 1 1 1 0 Neurogenesis glycoprotein Hydrolase_4 PF12146.8 OQS00364.1 - 1.4e-08 34.3 0.0 1.4e-05 24.5 0.0 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 OQS00364.1 - 0.0001 22.0 0.1 0.0013 18.5 0.0 2.2 1 1 1 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 OQS00364.1 - 0.012 16.2 0.0 0.06 13.9 0.1 1.7 1 1 0 1 1 1 0 Alpha/beta hydrolase family DUF818 PF05677.12 OQS00364.1 - 0.045 12.7 0.0 0.059 12.3 0.0 1.1 1 0 0 1 1 1 0 Chlamydia CHLPS protein (DUF818) MRF_C2 PF13888.6 OQS00364.1 - 0.2 11.5 0.0 0.7 9.8 0.0 1.7 2 0 0 2 2 2 0 Myelin gene regulatory factor C-terminal domain 2 MDD_C PF18376.1 OQS00365.1 - 0.1 12.3 0.0 0.15 11.8 0.0 1.3 1 0 0 1 1 1 0 Mevalonate 5-diphosphate decarboxylase C-terminal domain FYVE PF01363.21 OQS00366.1 - 1.1e-12 47.9 16.4 2.6e-12 46.7 16.4 1.7 1 0 0 1 1 1 1 FYVE zinc finger PulA_N1 PF17999.1 OQS00366.1 - 0.39 11.5 5.0 0.88 10.3 0.9 2.7 2 1 0 2 2 2 0 Pullulanase N1-terminal domain Methyltransf_31 PF13847.6 OQS00366.1 - 0.46 10.3 4.3 2.2 8.1 4.2 2.1 1 1 0 1 1 1 0 Methyltransferase domain PrmA PF06325.13 OQS00366.1 - 1.9 7.8 8.8 0.094 12.1 0.6 2.2 2 0 0 2 2 2 0 Ribosomal protein L11 methyltransferase (PrmA) DUF445 PF04286.12 OQS00367.1 - 0.13 12.0 12.2 0.16 11.7 12.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF445) DUF2423 PF10338.9 OQS00367.1 - 0.24 11.7 15.8 7.6 6.9 0.3 4.5 4 1 1 5 5 5 0 Protein of unknown function (DUF2423) DUF3349 PF11829.8 OQS00367.1 - 0.84 10.4 14.9 0.96 10.3 0.9 3.8 1 1 4 5 5 5 0 Protein of unknown function (DUF3349) YcgL PF05166.13 OQS00367.1 - 2.1 8.7 3.9 21 5.6 0.8 2.3 1 1 1 2 2 2 0 YcgL domain PemK_toxin PF02452.17 OQS00367.1 - 4.5 7.7 8.3 2.9 8.3 2.6 2.2 1 1 1 2 2 2 0 PemK-like, MazF-like toxin of type II toxin-antitoxin system DUF4962 PF16332.5 OQS00367.1 - 6.6 5.1 8.0 7.7 4.9 7.4 1.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4962) PGAP1 PF07819.13 OQS00368.1 - 5.1e-67 226.0 0.0 1.2e-66 224.8 0.0 1.7 1 0 0 1 1 1 1 PGAP1-like protein LRR_8 PF13855.6 OQS00368.1 - 4.3e-42 141.7 45.7 5.4e-10 38.9 1.4 7.9 4 1 3 7 7 7 7 Leucine rich repeat LRR_4 PF12799.7 OQS00368.1 - 2.4e-35 120.0 46.7 2.5e-05 24.5 0.1 9.9 7 2 1 9 9 9 8 Leucine Rich repeats (2 copies) EF-hand_6 PF13405.6 OQS00368.1 - 1.3e-12 46.6 8.2 5.7e-05 22.7 0.2 3.9 3 0 0 3 3 3 3 EF-hand domain EF-hand_1 PF00036.32 OQS00368.1 - 2.3e-12 45.5 5.8 4.5e-05 22.7 0.2 3.7 3 0 0 3 3 3 3 EF hand EF-hand_7 PF13499.6 OQS00368.1 - 3.8e-09 36.9 3.6 0.0026 18.2 0.1 3.2 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.6 OQS00368.1 - 2.7e-06 26.6 9.4 0.00092 18.6 0.2 3.0 3 0 0 3 3 3 2 EF hand DUF676 PF05057.14 OQS00368.1 - 0.00018 21.1 0.0 0.0004 20.0 0.0 1.5 1 0 0 1 1 1 1 Putative serine esterase (DUF676) EF-hand_8 PF13833.6 OQS00368.1 - 0.00039 20.2 7.3 0.0029 17.4 0.2 3.4 2 1 1 3 3 3 1 EF-hand domain pair EF-hand_10 PF14788.6 OQS00368.1 - 0.00054 19.8 0.4 0.039 13.8 0.1 2.8 1 1 1 2 2 2 2 EF hand LRR_1 PF00560.33 OQS00368.1 - 0.0019 18.5 45.2 2.3 9.1 0.2 13.5 13 1 1 14 14 14 1 Leucine Rich Repeat Abhydrolase_6 PF12697.7 OQS00368.1 - 0.012 16.2 0.1 0.037 14.6 0.1 1.9 1 0 0 1 1 1 0 Alpha/beta hydrolase family SPARC_Ca_bdg PF10591.9 OQS00368.1 - 0.028 14.7 4.9 0.048 14.0 0.2 3.2 2 0 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region SPATA25 PF15218.6 OQS00368.1 - 0.16 11.7 0.0 0.3 10.8 0.0 1.3 1 0 0 1 1 1 0 Spermatogenesis-associated protein 25 Thia_YuaJ PF09515.10 OQS00370.1 - 0.24 11.4 4.3 0.57 10.2 2.2 2.3 1 1 1 2 2 2 0 Thiamine transporter protein (Thia_YuaJ) SNase PF00565.17 OQS00371.1 - 1.6e-22 80.0 0.1 2.5e-22 79.4 0.1 1.3 1 0 0 1 1 1 1 Staphylococcal nuclease homologue Lac_bphage_repr PF06543.12 OQS00371.1 - 0.071 13.1 0.0 0.14 12.2 0.0 1.4 1 0 0 1 1 1 0 Lactococcus bacteriophage repressor ABC_membrane PF00664.23 OQS00372.1 - 1.5e-49 169.2 37.8 1.3e-27 97.2 5.3 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 OQS00372.1 - 4.9e-43 146.9 0.0 6.7e-25 88.2 0.0 2.4 2 0 0 2 2 2 2 ABC transporter AAA_16 PF13191.6 OQS00372.1 - 4.9e-07 30.3 0.1 0.00069 20.0 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 OQS00372.1 - 2.8e-05 24.1 0.1 0.36 10.7 0.0 2.7 2 1 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 OQS00372.1 - 0.00039 20.5 0.1 0.021 14.9 0.0 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_29 PF13555.6 OQS00372.1 - 0.00048 19.8 0.4 0.73 9.6 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 OQS00372.1 - 0.01 16.1 1.4 5.7 7.2 0.1 3.1 3 0 0 3 3 3 1 AAA domain RNA_helicase PF00910.22 OQS00372.1 - 0.023 15.1 0.1 1.7 9.1 0.0 2.7 2 0 0 2 2 2 0 RNA helicase IstB_IS21 PF01695.17 OQS00372.1 - 0.03 14.1 1.2 7.5 6.2 0.0 3.2 3 0 0 3 3 3 0 IstB-like ATP binding protein Roc PF08477.13 OQS00372.1 - 0.044 14.0 0.4 8.5 6.6 0.0 2.7 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_23 PF13476.6 OQS00372.1 - 0.059 13.9 0.7 6.2 7.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain DUF815 PF05673.13 OQS00372.1 - 0.079 12.1 0.1 3.3 6.8 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_25 PF13481.6 OQS00372.1 - 0.1 12.2 0.0 6.9 6.2 0.0 2.4 2 0 0 2 2 2 0 AAA domain SMC_N PF02463.19 OQS00372.1 - 0.23 10.8 7.2 1.9 7.8 0.1 3.2 4 0 0 4 4 4 0 RecF/RecN/SMC N terminal domain DUF87 PF01935.17 OQS00372.1 - 0.26 11.3 2.1 0.21 11.7 0.1 1.8 2 0 0 2 2 2 0 Helicase HerA, central domain AAA_30 PF13604.6 OQS00372.1 - 0.54 9.9 1.5 16 5.2 0.0 2.9 3 0 0 3 3 3 0 AAA domain His_Phos_1 PF00300.22 OQS00373.1 - 5.1e-17 62.2 0.5 9.2e-16 58.1 0.5 2.4 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) PH PF00169.29 OQS00373.1 - 4.5e-12 46.4 0.2 8.5e-12 45.5 0.2 1.5 1 0 0 1 1 1 1 PH domain PH_8 PF15409.6 OQS00373.1 - 9.8e-05 22.6 0.0 0.00021 21.5 0.0 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain PH_11 PF15413.6 OQS00373.1 - 0.0021 18.5 0.3 0.016 15.6 0.3 2.3 1 1 0 1 1 1 1 Pleckstrin homology domain PH_12 PF16457.5 OQS00373.1 - 0.014 16.0 0.1 0.036 14.6 0.0 1.8 1 1 0 1 1 1 0 Pleckstrin homology domain His_Phos_2 PF00328.22 OQS00373.1 - 0.026 13.9 0.0 0.03 13.7 0.0 1.2 1 0 0 1 1 1 0 Histidine phosphatase superfamily (branch 2) PH_9 PF15410.6 OQS00373.1 - 0.093 13.1 0.2 6.3 7.2 0.2 2.5 1 1 0 1 1 1 0 Pleckstrin homology domain PAN_1 PF00024.26 OQS00374.1 - 4.2e-11 42.7 7.1 0.0044 17.0 0.0 4.3 4 1 1 5 5 5 3 PAN domain PAN_4 PF14295.6 OQS00374.1 - 1.1e-06 28.4 8.2 0.0022 17.9 0.1 3.6 3 0 0 3 3 3 3 PAN domain PIG-L PF02585.17 OQS00374.1 - 1.1e-06 29.2 0.4 3.9e-06 27.5 0.4 1.9 1 1 0 1 1 1 1 GlcNAc-PI de-N-acetylase INCENP_ARK-bind PF03941.15 OQS00375.1 - 1.5e-11 44.1 0.1 1.5e-11 44.1 0.1 2.2 3 0 0 3 3 3 1 Inner centromere protein, ARK binding region Cystatin PF00031.21 OQS00376.1 - 3.1e-13 49.8 5.2 8.5e-05 22.7 0.7 3.5 3 0 0 3 3 3 3 Cystatin domain SQAPI PF16845.5 OQS00376.1 - 9.3e-06 25.9 5.7 1.9 8.9 0.0 4.4 4 1 0 4 4 4 3 Aspartic acid proteinase inhibitor Redoxin PF08534.10 OQS00377.1 - 1.2e-30 106.2 0.0 1.4e-30 105.9 0.0 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 OQS00377.1 - 3e-07 30.4 0.0 3.6e-07 30.1 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family PKcGMP_CC PF16808.5 OQS00378.1 - 0.0087 15.9 7.0 0.17 11.8 1.3 3.1 2 0 0 2 2 2 2 Coiled-coil N-terminus of cGMP-dependent protein kinase YojJ PF10372.9 OQS00378.1 - 0.034 14.2 8.5 0.034 14.2 1.4 3.1 3 0 0 3 3 3 0 Bacterial membrane-spanning protein N-terminus PLA2_B PF01735.18 OQS00378.1 - 0.15 10.5 0.3 0.3 9.5 0.3 1.4 1 0 0 1 1 1 0 Lysophospholipase catalytic domain zf-3CxxC PF13695.6 OQS00378.1 - 0.23 12.0 0.9 0.68 10.4 0.2 2.2 2 0 0 2 2 2 0 Zinc-binding domain Csm1_N PF18504.1 OQS00378.1 - 7.3 7.0 15.7 0.16 12.3 0.8 4.0 3 1 1 4 4 4 0 Csm1 N-terminal domain Mem_trans PF03547.18 OQS00379.1 - 0.043 12.2 0.1 0.056 11.8 0.1 1.3 1 0 0 1 1 1 0 Membrane transport protein LRR_4 PF12799.7 OQS00380.1 - 1.1e-09 38.4 13.5 2.5e-05 24.5 1.8 3.3 1 1 4 5 5 5 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 OQS00380.1 - 5.6e-07 29.2 8.1 1.4e-05 24.8 3.5 2.6 2 1 1 3 3 3 2 Leucine rich repeat LRR_9 PF14580.6 OQS00380.1 - 2.5e-05 23.8 0.4 4.1e-05 23.2 0.4 1.3 1 0 0 1 1 1 1 Leucine-rich repeat N6-adenineMlase PF10237.9 OQS00381.1 - 4.3e-28 98.2 0.4 5e-28 97.9 0.4 1.0 1 0 0 1 1 1 1 Probable N6-adenine methyltransferase FAM194 PF14977.6 OQS00383.1 - 4.4e-09 36.0 0.0 4.7e-09 35.9 0.0 1.1 1 0 0 1 1 1 1 FAM194 protein Redoxin PF08534.10 OQS00384.1 - 9.6e-06 25.4 0.0 1e-05 25.3 0.0 1.0 1 0 0 1 1 1 1 Redoxin Cystatin PF00031.21 OQS00385.1 - 1.5e-08 34.8 3.1 0.002 18.3 0.1 2.7 2 1 0 2 2 2 2 Cystatin domain SQAPI PF16845.5 OQS00385.1 - 8.8e-05 22.8 0.5 0.33 11.3 0.0 3.0 3 0 0 3 3 3 2 Aspartic acid proteinase inhibitor CHB_HEX_C PF03174.13 OQS00385.1 - 0.066 13.2 0.3 0.2 11.6 0.0 2.0 2 0 0 2 2 2 0 Chitobiase/beta-hexosaminidase C-terminal domain Aminotran_5 PF00266.19 OQS00387.1 - 4.8e-36 124.5 0.0 1.5e-25 90.0 0.0 2.4 2 0 0 2 2 2 2 Aminotransferase class-V Aminotran_1_2 PF00155.21 OQS00387.1 - 7e-05 22.2 0.0 0.00012 21.4 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class I and II Lactamase_B_2 PF12706.7 OQS00388.1 - 7.2e-33 113.8 0.2 1.1e-32 113.2 0.0 1.4 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 OQS00388.1 - 1e-11 45.0 0.0 1.4e-11 44.6 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 OQS00388.1 - 0.038 14.0 0.7 0.14 12.2 0.1 2.2 2 1 0 2 2 2 0 Metallo-beta-lactamase superfamily Pkinase PF00069.25 OQS00389.1 - 1.7e-70 237.4 0.0 2.6e-70 236.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain NIF PF03031.18 OQS00389.1 - 2.9e-41 140.8 0.8 5.4e-41 140.0 0.8 1.5 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Pkinase_Tyr PF07714.17 OQS00389.1 - 1.9e-39 135.5 0.0 3.1e-39 134.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase HAD_2 PF13419.6 OQS00389.1 - 0.03 14.4 0.0 0.073 13.1 0.0 1.6 1 1 0 1 1 1 0 Haloacid dehalogenase-like hydrolase Acid_PPase PF12689.7 OQS00389.1 - 0.037 13.9 0.1 0.1 12.4 0.1 1.8 1 0 0 1 1 1 0 Acid Phosphatase Kdo PF06293.14 OQS00389.1 - 0.048 13.0 1.0 3.1 7.1 0.0 3.5 4 0 0 4 4 4 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 OQS00389.1 - 0.084 12.2 0.0 0.25 10.6 0.0 1.7 1 1 0 1 1 1 0 Kinase-like Sec23_trunk PF04811.15 OQS00391.1 - 2.2e-72 243.6 0.0 3.1e-72 243.0 0.0 1.2 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_BS PF08033.12 OQS00391.1 - 6.1e-29 100.6 0.0 1.2e-28 99.7 0.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain Sec23_helical PF04815.15 OQS00391.1 - 1.1e-21 76.6 0.0 3.5e-21 75.0 0.0 2.0 1 0 0 1 1 1 1 Sec23/Sec24 helical domain zf-Sec23_Sec24 PF04810.15 OQS00391.1 - 3.6e-16 58.9 3.3 6.9e-16 58.0 3.3 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 OQS00391.1 - 9.2e-12 44.7 0.0 9.2e-12 44.7 0.0 2.1 2 0 0 2 2 2 1 Gelsolin repeat Paramyxo_P PF01806.17 OQS00391.1 - 0.11 11.9 0.0 0.22 10.9 0.0 1.4 1 0 0 1 1 1 0 Paramyxovirinae P phosphoprotein C-terminal region RNA_pol_Rpb1_5 PF04998.17 OQS00392.1 - 9.6e-88 294.1 0.2 1.5e-87 293.4 0.2 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_1 PF04997.12 OQS00392.1 - 8.7e-86 288.1 0.2 2e-85 286.9 0.2 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_2 PF00623.20 OQS00392.1 - 1.9e-75 252.6 0.1 3.5e-75 251.8 0.1 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.18 OQS00392.1 - 3.4e-37 127.8 0.0 1.1e-36 126.2 0.0 1.9 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.17 OQS00392.1 - 1.2e-27 96.0 0.0 3.1e-27 94.7 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 Fringe PF02434.16 OQS00392.1 - 1.3e-07 31.3 0.1 2.5e-07 30.4 0.1 1.4 1 0 0 1 1 1 1 Fringe-like WASH-7_mid PF14744.6 OQS00393.1 - 8e-140 465.8 4.1 8e-140 465.8 4.1 2.5 3 0 0 3 3 3 1 WASH complex subunit 7 WASH-7_N PF14745.6 OQS00393.1 - 2.5e-122 409.3 0.0 4.7e-122 408.4 0.0 1.5 1 0 0 1 1 1 1 WASH complex subunit 7, N-terminal WASH-7_C PF14746.6 OQS00393.1 - 3.8e-50 170.0 3.9 3.8e-50 170.0 3.9 2.5 3 0 0 3 3 3 1 WASH complex subunit 7, C-terminal CENP-B_dimeris PF09026.10 OQS00393.1 - 1.4 9.4 6.7 7.8 7.0 6.7 2.3 1 0 0 1 1 1 0 Centromere protein B dimerisation domain WW PF00397.26 OQS00420.1 - 1.3e-16 60.3 13.4 2e-08 34.2 3.0 2.5 2 0 0 2 2 2 2 WW domain Glyco_hyd_101C PF17451.2 OQS00420.1 - 0.16 12.3 4.0 3.8 7.8 0.2 2.6 2 0 0 2 2 2 0 Glycosyl hydrolase 101 beta sandwich domain Glucan_synthase PF02364.15 OQS00421.1 - 4.5e-187 623.8 8.4 5e-165 550.9 4.2 2.7 1 1 1 2 2 2 2 1,3-beta-glucan synthase component FKS1_dom1 PF14288.6 OQS00421.1 - 2.5e-23 82.8 1.9 1.4e-21 77.2 0.8 3.5 2 1 0 2 2 2 1 1,3-beta-glucan synthase subunit FKS1, domain-1 EF-hand_5 PF13202.6 OQS00421.1 - 0.073 12.6 0.0 1.5 8.4 0.0 2.5 2 0 0 2 2 2 0 EF hand AAA_33 PF13671.6 OQS00421.1 - 0.12 12.5 0.2 0.88 9.7 0.0 2.3 2 0 0 2 2 2 0 AAA domain MIT PF04212.18 OQS00421.1 - 0.17 12.0 0.6 0.5 10.5 0.6 1.8 1 0 0 1 1 1 0 MIT (microtubule interacting and transport) domain Acetyltransf_7 PF13508.7 OQS00422.1 - 1.8e-05 25.0 0.0 2.9e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 OQS00422.1 - 0.00011 22.4 0.0 0.00017 21.8 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 OQS00422.1 - 0.0055 16.6 0.0 0.01 15.8 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain YjgF_endoribonc PF14588.6 OQS00423.1 - 2e-27 96.2 0.0 2.3e-27 96.0 0.0 1.0 1 0 0 1 1 1 1 YjgF/chorismate_mutase-like, putative endoribonuclease Ribonuc_L-PSP PF01042.21 OQS00423.1 - 4e-17 62.4 0.0 5.4e-17 61.9 0.0 1.1 1 0 0 1 1 1 1 Endoribonuclease L-PSP Pam16 PF03656.13 OQS00424.1 - 1.2e-20 73.8 0.1 1.4e-20 73.6 0.1 1.1 1 0 0 1 1 1 1 Pam16 DUF4441 PF14536.6 OQS00424.1 - 0.062 13.5 0.3 0.093 12.9 0.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4441) Pkinase PF00069.25 OQS00425.1 - 1.6e-52 178.5 0.0 4.8e-52 176.9 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQS00425.1 - 5.4e-33 114.4 0.0 1.4e-31 109.7 0.0 2.3 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OQS00425.1 - 4.1e-07 29.6 0.0 7.9e-07 28.7 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 OQS00425.1 - 0.0017 17.2 0.0 0.0037 16.1 0.0 1.5 2 0 0 2 2 2 1 Fungal protein kinase Haspin_kinase PF12330.8 OQS00425.1 - 0.036 13.0 0.0 0.067 12.1 0.0 1.4 1 0 0 1 1 1 0 Haspin like kinase domain APH PF01636.23 OQS00425.1 - 0.13 12.1 0.1 0.28 11.1 0.1 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family DegT_DnrJ_EryC1 PF01041.17 OQS00426.1 - 8.7e-31 107.5 0.0 1.3e-26 93.8 0.0 2.1 2 0 0 2 2 2 2 DegT/DnrJ/EryC1/StrS aminotransferase family PLAC8 PF04749.17 OQS00426.1 - 5.4e-18 65.8 5.0 6.8e-18 65.5 3.8 1.8 2 0 0 2 2 2 1 PLAC8 family Aminotran_5 PF00266.19 OQS00426.1 - 0.007 15.4 0.1 0.012 14.6 0.1 1.3 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 OQS00426.1 - 0.015 14.5 0.0 0.022 13.9 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class I and II DUF2614 PF11023.8 OQS00426.1 - 0.092 12.8 0.2 0.2 11.8 0.2 1.5 1 0 0 1 1 1 0 Zinc-ribbon containing domain FixP_N PF14715.6 OQS00426.1 - 1.4 8.8 4.8 3.2 7.6 4.8 1.6 1 0 0 1 1 1 0 N-terminal domain of cytochrome oxidase-cbb3, FixP Myosin_head PF00063.21 OQS00427.1 - 2e-217 723.7 0.1 3.1e-217 723.0 0.1 1.3 1 0 0 1 1 1 1 Myosin head (motor domain) IQ PF00612.27 OQS00427.1 - 5.2e-09 35.1 28.5 0.0045 16.7 1.5 5.8 5 0 0 5 5 5 4 IQ calmodulin-binding motif Myosin_N PF02736.19 OQS00427.1 - 5.6e-06 26.1 0.2 1.4e-05 24.8 0.2 1.6 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain DivIC PF04977.15 OQS00427.1 - 0.0014 18.3 10.8 0.047 13.5 0.2 3.9 3 0 0 3 3 3 2 Septum formation initiator AAA_22 PF13401.6 OQS00427.1 - 0.067 13.5 0.8 0.43 10.8 0.0 2.8 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 OQS00427.1 - 0.073 13.5 0.0 0.26 11.7 0.0 2.0 1 0 0 1 1 1 0 RNA helicase AAA_16 PF13191.6 OQS00427.1 - 0.074 13.4 4.0 0.28 11.6 0.0 3.0 3 0 0 3 3 3 0 AAA ATPase domain Hpr_kinase_C PF07475.12 OQS00427.1 - 0.096 12.2 0.1 4 6.9 0.0 2.5 2 0 0 2 2 2 0 HPr Serine kinase C-terminal domain AAA_18 PF13238.6 OQS00427.1 - 0.12 12.9 3.2 0.54 10.8 0.0 3.5 4 0 0 4 4 4 0 AAA domain ABC_tran PF00005.27 OQS00427.1 - 0.87 10.1 3.9 1.8 9.1 0.0 3.0 2 1 0 2 2 2 0 ABC transporter ZapB PF06005.12 OQS00427.1 - 1.3 9.6 30.8 0.49 10.9 1.0 4.9 3 1 1 4 4 4 0 Cell division protein ZapB His_Phos_2 PF00328.22 OQS00428.1 - 1.9e-10 40.7 3.0 5.1e-05 22.8 1.9 3.0 2 1 0 2 2 2 2 Histidine phosphatase superfamily (branch 2) EIID-AGA PF03613.14 OQS00428.1 - 0.15 11.3 0.0 0.22 10.7 0.0 1.2 1 0 0 1 1 1 0 PTS system mannose/fructose/sorbose family IID component HA2 PF04408.23 OQS00430.1 - 1e-21 77.2 0.0 1e-21 77.2 0.0 3.1 3 0 0 3 3 2 1 Helicase associated domain (HA2) CBM_1 PF00734.18 OQS00430.1 - 3.9e-17 61.9 61.0 5.1e-09 35.9 9.6 6.3 6 0 0 6 6 6 4 Fungal cellulose binding domain OB_NTP_bind PF07717.16 OQS00430.1 - 6.8e-13 48.8 0.0 1.8e-12 47.4 0.0 1.8 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 OQS00430.1 - 9.8e-11 42.0 0.0 2.5e-10 40.7 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 OQS00430.1 - 1.9e-06 27.7 0.1 4.7e-06 26.5 0.1 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 OQS00430.1 - 0.0002 21.6 0.2 0.00068 19.9 0.2 1.9 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 OQS00430.1 - 0.0046 16.7 0.0 0.0087 15.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 OQS00430.1 - 0.0051 17.2 0.1 0.012 15.9 0.1 1.6 1 0 0 1 1 1 1 AAA domain Flavi_DEAD PF07652.14 OQS00430.1 - 0.013 15.4 0.3 0.035 14.1 0.0 1.9 2 0 0 2 2 2 0 Flavivirus DEAD domain DUF2075 PF09848.9 OQS00430.1 - 0.015 14.5 0.0 0.032 13.5 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) T2SSE PF00437.20 OQS00430.1 - 0.022 13.9 0.0 0.04 13.0 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein ResIII PF04851.15 OQS00430.1 - 0.036 14.1 0.2 9.2 6.2 0.0 2.8 3 0 0 3 3 2 0 Type III restriction enzyme, res subunit AAA_14 PF13173.6 OQS00430.1 - 0.05 13.6 0.1 0.23 11.5 0.1 2.1 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.27 OQS00430.1 - 0.056 14.0 0.0 0.19 12.2 0.0 1.9 1 0 0 1 1 1 0 ABC transporter AAA_7 PF12775.7 OQS00430.1 - 0.056 13.0 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region PhoH PF02562.16 OQS00430.1 - 0.065 12.7 0.0 0.14 11.6 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein AAA_33 PF13671.6 OQS00430.1 - 0.073 13.2 0.0 0.073 13.2 0.0 3.3 4 0 0 4 4 3 0 AAA domain Sigma54_activat PF00158.26 OQS00430.1 - 0.17 11.6 0.0 0.42 10.3 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_23 PF13476.6 OQS00430.1 - 0.17 12.3 0.0 0.17 12.3 0.0 2.8 3 1 0 3 3 1 0 AAA domain RTC PF01137.21 OQS00483.1 - 8.5e-57 191.9 0.0 9.8e-57 191.7 0.0 1.0 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase RTC_insert PF05189.13 OQS00483.1 - 1.5e-35 121.8 0.0 2.6e-35 121.0 0.0 1.4 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain TIG PF01833.24 OQS00484.1 - 3.4e-123 402.0 153.9 3.9e-10 39.7 0.1 24.3 24 0 0 24 24 24 21 IPT/TIG domain TIG_plexin PF17960.1 OQS00484.1 - 8.2e-31 105.9 39.9 0.076 13.0 0.0 21.1 23 0 0 23 23 23 9 TIG domain Anth_Ig PF05587.13 OQS00484.1 - 1.2e-10 41.6 18.1 0.0024 18.2 0.0 9.1 11 0 0 11 11 11 3 Anthrax receptor extracellular domain Ephrin_rec_like PF07699.13 OQS00484.1 - 9.9e-06 25.2 8.9 0.00011 21.9 1.9 9.5 7 3 2 9 9 9 4 Putative ephrin-receptor like RHD_dimer PF16179.5 OQS00484.1 - 0.021 14.8 0.7 21 5.2 0.0 5.4 6 0 0 6 6 6 0 Rel homology dimerisation domain TSGP1 PF07771.11 OQS00484.1 - 2.1 8.5 6.5 7 6.8 6.5 1.9 1 0 0 1 1 1 0 Tick salivary peptide group 1 Fumble PF03630.14 OQS00485.1 - 1e-116 389.8 1.6 1.2e-116 389.6 1.6 1.0 1 0 0 1 1 1 1 Fumble FA_hydroxylase PF04116.13 OQS00487.1 - 9.9e-30 103.6 16.2 1.3e-29 103.2 16.2 1.1 1 0 0 1 1 1 1 Fatty acid hydroxylase superfamily CTP_transf_3 PF02348.19 OQS00488.1 - 2.4e-43 148.6 0.0 3.1e-43 148.3 0.0 1.0 1 0 0 1 1 1 1 Cytidylyltransferase NTP_transf_3 PF12804.7 OQS00488.1 - 7.9e-08 32.8 0.1 1.2e-07 32.2 0.1 1.2 1 0 0 1 1 1 1 MobA-like NTP transferase domain IspD PF01128.19 OQS00488.1 - 2.9e-06 27.2 0.2 8.3e-05 22.4 0.3 2.0 2 0 0 2 2 2 1 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase NTP_transferase PF00483.23 OQS00488.1 - 0.018 14.6 0.1 0.026 14.1 0.1 1.1 1 0 0 1 1 1 0 Nucleotidyl transferase DUF2064 PF09837.9 OQS00488.1 - 0.027 14.3 0.1 0.042 13.7 0.1 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2064) SPX PF03105.19 OQS00489.1 - 5.7e-25 89.0 17.9 1.1e-13 51.8 1.1 3.0 1 1 2 3 3 3 3 SPX domain TyeA PF09059.10 OQS00489.1 - 0.017 15.2 1.7 4.9 7.3 0.2 3.1 1 1 3 4 4 4 0 TyeA Afaf PF15339.6 OQS00489.1 - 0.028 14.1 0.9 4.4 7.0 0.1 2.2 2 0 0 2 2 2 0 Acrosome formation-associated factor His_Phos_2 PF00328.22 OQS00490.1 - 2.7e-21 76.4 0.0 1.7e-16 60.6 0.0 2.4 2 0 0 2 2 2 2 Histidine phosphatase superfamily (branch 2) DNA_ligase_A_M PF01068.21 OQS00490.1 - 0.13 11.9 0.0 0.29 10.7 0.0 1.5 1 0 0 1 1 1 0 ATP dependent DNA ligase domain rRNA_proc-arch PF13234.6 OQS00492.1 - 4.1e-70 236.8 0.0 8.8e-70 235.7 0.0 1.6 1 0 0 1 1 1 1 rRNA-processing arch domain DSHCT PF08148.12 OQS00492.1 - 3.2e-50 170.0 0.3 7.1e-50 168.9 0.3 1.6 1 0 0 1 1 1 1 DSHCT (NUC185) domain DEAD PF00270.29 OQS00492.1 - 4.7e-19 68.8 0.0 2.5e-18 66.5 0.0 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OQS00492.1 - 3.4e-07 30.6 0.0 5.1e-06 26.8 0.0 2.8 1 1 0 1 1 1 1 Helicase conserved C-terminal domain ATPase_2 PF01637.18 OQS00492.1 - 0.14 12.0 0.8 0.49 10.3 0.0 2.3 3 0 0 3 3 3 0 ATPase domain predominantly from Archaea TPR_11 PF13414.6 OQS00493.1 - 0.0098 15.6 0.4 0.021 14.5 0.4 1.5 1 0 0 1 1 1 1 TPR repeat Peptidase_S10 PF00450.22 OQS00521.1 - 5.7e-52 177.5 3.3 9.8e-37 127.3 1.3 2.0 1 1 1 2 2 2 2 Serine carboxypeptidase LRR_6 PF13516.6 OQS00522.1 - 2.3e-43 142.6 41.9 6.8e-05 22.6 0.1 17.0 18 0 0 18 18 18 12 Leucine Rich repeat PAC2 PF09754.9 OQS00522.1 - 3.6e-11 43.5 0.0 1.5e-09 38.2 0.0 2.6 3 0 0 3 3 3 1 PAC2 family LRR_4 PF12799.7 OQS00522.1 - 2.9e-10 40.2 35.8 0.0023 18.3 0.0 10.4 8 4 2 11 11 11 5 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 OQS00522.1 - 6.4e-10 38.2 21.0 17 6.4 0.0 14.3 16 1 0 16 16 16 2 Leucine Rich Repeat LRR_8 PF13855.6 OQS00522.1 - 4.4e-07 29.6 39.3 0.064 13.0 0.3 10.3 8 5 0 8 8 8 4 Leucine rich repeat EF_TS PF00889.19 OQS00523.1 - 7.4e-53 179.3 1.6 1e-52 178.8 1.6 1.2 1 0 0 1 1 1 1 Elongation factor TS SAP30_Sin3_bdg PF13867.6 OQS00524.1 - 2e-12 47.2 0.9 3.4e-12 46.5 0.1 1.8 2 0 0 2 2 2 1 Sin3 binding region of histone deacetylase complex subunit SAP30 PHD PF00628.29 OQS00524.1 - 2e-06 27.6 6.3 2e-06 27.6 6.3 1.7 2 0 0 2 2 2 1 PHD-finger DUF2151 PF10221.9 OQS00524.1 - 0.038 12.6 1.9 0.051 12.2 1.9 1.1 1 0 0 1 1 1 0 Cell cycle and development regulator TMEM51 PF15345.6 OQS00524.1 - 0.78 9.5 6.5 1.9 8.3 6.5 1.8 1 1 0 1 1 1 0 Transmembrane protein 51 PHD_2 PF13831.6 OQS00524.1 - 0.81 9.3 5.9 0.16 11.6 1.8 2.0 2 1 0 2 2 2 0 PHD-finger Peptidase_S9_N PF02897.15 OQS00525.1 - 4.2e-55 187.2 6.4 1.9e-54 185.1 6.4 1.9 1 1 0 1 1 1 1 Prolyl oligopeptidase, N-terminal beta-propeller domain Peptidase_S9 PF00326.21 OQS00525.1 - 2.1e-49 167.9 0.0 3.7e-49 167.1 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family CRAL_TRIO PF00650.20 OQS00525.1 - 9e-32 110.0 0.1 2.4e-31 108.6 0.1 1.8 1 0 0 1 1 1 1 CRAL/TRIO domain FYVE PF01363.21 OQS00525.1 - 2e-12 47.1 3.4 6.3e-12 45.4 3.4 1.8 1 0 0 1 1 1 1 FYVE zinc finger CRAL_TRIO_2 PF13716.6 OQS00525.1 - 3.9e-05 23.8 0.0 0.00013 22.1 0.0 1.9 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain PD40 PF07676.12 OQS00525.1 - 0.0048 16.8 0.0 0.011 15.6 0.0 1.6 1 0 0 1 1 1 1 WD40-like Beta Propeller Repeat DUF4945 PF16303.5 OQS00525.1 - 0.022 14.7 0.1 0.094 12.6 0.1 2.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4945) FYVE_2 PF02318.16 OQS00525.1 - 0.06 13.6 3.5 0.17 12.1 3.5 1.8 1 0 0 1 1 1 0 FYVE-type zinc finger PH PF00169.29 OQS00525.1 - 0.08 13.5 0.0 3.7 8.1 0.0 2.9 2 0 0 2 2 2 0 PH domain Fe_hyd_lg_C PF02906.14 OQS00525.1 - 0.15 11.7 0.0 0.38 10.4 0.0 1.7 1 0 0 1 1 1 0 Iron only hydrogenase large subunit, C-terminal domain Lactonase PF10282.9 OQS00526.1 - 7.6e-85 285.2 0.0 8.5e-85 285.0 0.0 1.0 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller Big_11 PF18200.1 OQS00526.1 - 0.018 14.9 0.0 9.6 6.2 0.0 3.4 3 0 0 3 3 3 0 Bacterial Ig-like domain zf-C2H2 PF00096.26 OQS00527.1 - 2.4e-16 59.2 26.5 9.8e-05 22.6 2.5 4.4 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 OQS00527.1 - 2.7e-15 56.0 24.4 1.9e-05 24.9 0.4 5.1 5 0 0 5 5 5 4 Zinc-finger double domain BET PF17035.5 OQS00527.1 - 1.1e-12 47.9 0.1 2.4e-12 46.8 0.1 1.5 1 0 0 1 1 1 1 Bromodomain extra-terminal - transcription regulation zf-C2H2_4 PF13894.6 OQS00527.1 - 1.4e-08 34.8 24.2 0.0089 16.8 1.6 4.6 4 0 0 4 4 4 4 C2H2-type zinc finger zf-met PF12874.7 OQS00527.1 - 0.00018 21.7 14.2 0.0097 16.3 0.9 4.4 4 0 0 4 4 4 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 OQS00527.1 - 0.00058 20.1 0.7 0.00058 20.1 0.7 3.9 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding zf-TRAF PF02176.18 OQS00527.1 - 0.0016 19.1 10.1 0.15 12.8 3.3 2.3 2 0 0 2 2 2 2 TRAF-type zinc finger zf-C2H2_8 PF15909.5 OQS00527.1 - 0.055 13.8 10.3 3.5 8.0 0.3 3.4 1 1 2 3 3 3 0 C2H2-type zinc ribbon PRP21_like_P PF12230.8 OQS00527.1 - 0.26 11.1 4.6 0.43 10.4 4.6 1.3 1 0 0 1 1 1 0 Pre-mRNA splicing factor PRP21 like protein FOXP-CC PF16159.5 OQS00527.1 - 0.35 11.5 0.1 0.35 11.5 0.1 4.2 3 1 2 5 5 5 0 FOXP coiled-coil domain zf-C2H2_aberr PF17017.5 OQS00527.1 - 0.48 10.6 7.4 5.5 7.1 0.1 3.4 1 1 2 3 3 3 0 Aberrant zinc-finger ArfGap PF01412.18 OQS00528.1 - 1.9e-32 111.8 0.0 3.4e-32 111.0 0.0 1.4 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf SCHIP-1 PF10148.9 OQS00528.1 - 0.63 9.6 0.0 0.63 9.6 0.0 2.2 2 1 1 3 3 3 0 Schwannomin-interacting protein 1 CEL_III_C PF18054.1 OQS00528.1 - 5.2 7.1 6.1 1.8 8.6 2.4 2.0 1 1 1 2 2 2 0 CEL-III C-terminal Rap_GAP PF02145.15 OQS00529.1 - 3.2e-53 180.0 0.0 6.3e-53 179.1 0.0 1.5 1 0 0 1 1 1 1 Rap/ran-GAP RGS PF00615.19 OQS00529.1 - 0.00012 22.3 1.9 0.00022 21.5 0.5 2.1 2 0 0 2 2 2 1 Regulator of G protein signaling domain DUF29 PF01724.16 OQS00529.1 - 0.0042 17.3 0.0 0.62 10.3 0.0 2.8 2 0 0 2 2 2 1 Domain of unknown function DUF29 PhaP_Bmeg PF09602.10 OQS00530.1 - 0.016 15.1 0.1 0.021 14.8 0.1 1.1 1 0 0 1 1 1 0 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) Pga1 PF10333.9 OQS00530.1 - 0.018 14.9 0.1 0.02 14.7 0.1 1.0 1 0 0 1 1 1 0 GPI-Mannosyltransferase II co-activator BTB PF00651.31 OQS00530.1 - 0.032 14.5 0.0 0.041 14.1 0.0 1.1 1 0 0 1 1 1 0 BTB/POZ domain Ank_2 PF12796.7 OQS00531.1 - 6e-05 23.6 0.0 0.00098 19.7 0.0 2.4 2 1 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OQS00531.1 - 0.00053 20.2 0.0 24 5.4 0.0 4.1 2 1 2 4 4 4 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 OQS00531.1 - 0.0036 17.9 0.0 0.85 10.3 0.0 3.2 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Thr_dehydrat_C PF00585.18 OQS00531.1 - 0.083 12.7 0.0 0.18 11.6 0.0 1.5 1 0 0 1 1 1 0 C-terminal regulatory domain of Threonine dehydratase Ank_3 PF13606.6 OQS00531.1 - 0.1 13.2 0.0 50 5.0 0.0 3.7 4 0 0 4 4 4 0 Ankyrin repeat Kinesin PF00225.23 OQS00532.1 - 1.1e-98 330.3 3.5 1.1e-98 330.3 3.5 2.6 3 0 0 3 3 3 1 Kinesin motor domain Microtub_bd PF16796.5 OQS00532.1 - 1.1e-24 87.0 0.0 6.8e-24 84.5 0.0 2.5 1 0 0 1 1 1 1 Microtubule binding HEAT PF02985.22 OQS00532.1 - 1.7e-12 46.4 6.7 0.012 15.9 0.1 6.2 6 0 0 6 6 6 3 HEAT repeat HEAT_EZ PF13513.6 OQS00532.1 - 7.6e-08 32.7 0.9 0.17 12.4 0.0 4.7 4 0 0 4 4 4 3 HEAT-like repeat HEAT_2 PF13646.6 OQS00532.1 - 6.4e-05 23.3 0.1 2 8.9 0.0 4.6 3 1 0 4 4 4 1 HEAT repeats ZapB PF06005.12 OQS00532.1 - 9.1 6.8 38.4 3.3 8.2 13.2 5.5 4 2 2 6 6 6 0 Cell division protein ZapB EF-hand_6 PF13405.6 OQS00533.1 - 6.1e-10 38.2 1.9 0.00025 20.7 0.2 3.3 3 0 0 3 3 3 2 EF-hand domain EF-hand_1 PF00036.32 OQS00533.1 - 1.5e-08 33.6 2.6 0.00018 20.9 0.2 2.6 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 OQS00533.1 - 8.7e-07 28.7 1.0 0.017 15.0 0.1 2.5 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_7 PF13499.6 OQS00533.1 - 1.3e-06 28.8 1.1 3.7e-06 27.3 1.0 1.9 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.6 OQS00533.1 - 0.0017 17.8 1.2 0.0056 16.1 0.2 2.3 2 0 0 2 2 2 1 EF hand EF-hand_10 PF14788.6 OQS00533.1 - 0.053 13.4 2.2 0.31 11.0 0.5 2.7 3 0 0 3 3 3 0 EF hand Trypan_PARP PF05887.11 OQS00533.1 - 0.33 10.9 5.4 0.53 10.3 5.4 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) LRR_6 PF13516.6 OQS00534.1 - 4.7e-16 57.4 10.7 1.3e-05 24.8 0.1 5.5 5 0 0 5 5 5 3 Leucine Rich repeat LRR_1 PF00560.33 OQS00534.1 - 0.0039 17.5 0.4 61 4.7 0.0 5.0 5 0 0 5 5 5 0 Leucine Rich Repeat LRR_8 PF13855.6 OQS00534.1 - 0.025 14.3 12.5 1.2 9.0 0.2 4.8 3 1 2 5 5 5 0 Leucine rich repeat LRR_4 PF12799.7 OQS00534.1 - 0.075 13.5 12.9 0.31 11.5 0.5 4.2 4 1 1 5 5 5 0 Leucine Rich repeats (2 copies) Peptidase_C69 PF03577.15 OQS00535.1 - 1e-48 166.2 0.0 3.1e-48 164.7 0.0 1.8 1 1 0 1 1 1 1 Peptidase family C69 FYVE PF01363.21 OQS00536.1 - 8.7e-21 73.8 7.0 1.5e-20 73.1 7.0 1.4 1 0 0 1 1 1 1 FYVE zinc finger C2 PF00168.30 OQS00536.1 - 1.2e-16 60.9 0.0 2e-16 60.1 0.0 1.4 1 0 0 1 1 1 1 C2 domain FYVE_2 PF02318.16 OQS00536.1 - 1.8e-05 24.9 5.7 2.4e-05 24.6 4.5 1.7 2 0 0 2 2 2 1 FYVE-type zinc finger Pex24p PF06398.11 OQS00536.1 - 0.004 16.2 8.2 0.008 15.2 7.8 1.5 1 1 1 2 2 2 1 Integral peroxisomal membrane peroxin DUF639 PF04842.12 OQS00536.1 - 0.015 14.7 6.8 0.91 8.9 2.0 2.2 2 0 0 2 2 2 0 Plant protein of unknown function (DUF639) PRT_C PF08372.10 OQS00536.1 - 0.066 13.0 5.4 1.8 8.3 0.6 2.5 2 0 0 2 2 2 0 Plant phosphoribosyltransferase C-terminal Reticulon PF02453.17 OQS00536.1 - 2.8 7.9 10.0 13 5.7 10.0 1.9 1 1 0 1 1 1 0 Reticulon zf-B_box PF00643.24 OQS00536.1 - 7.5 6.8 11.1 6.4 7.0 6.2 2.5 2 0 0 2 2 2 0 B-box zinc finger HEAT_EZ PF13513.6 OQS00575.1 - 0.00024 21.5 7.3 1.2 9.7 0.0 5.3 5 0 0 5 5 5 3 HEAT-like repeat 7TMR-HDED PF07697.11 OQS00575.1 - 0.025 14.7 4.2 0.064 13.4 4.2 1.6 1 0 0 1 1 1 0 7TM-HD extracellular DUF3385 PF11865.8 OQS00575.1 - 0.038 13.9 0.4 1.4 8.8 0.0 3.3 2 1 0 2 2 2 0 Domain of unknown function (DUF3385) TPR_12 PF13424.6 OQS00577.1 - 6.7e-37 125.6 7.7 1.9e-14 53.7 2.3 5.9 4 1 2 6 6 6 6 Tetratricopeptide repeat TPR_10 PF13374.6 OQS00577.1 - 7e-35 117.9 22.1 1.6e-08 34.1 2.5 9.6 9 0 0 9 9 9 6 Tetratricopeptide repeat CHAT PF12770.7 OQS00577.1 - 3.5e-12 46.3 0.2 7.4e-12 45.3 0.2 1.5 1 0 0 1 1 1 1 CHAT domain TPR_1 PF00515.28 OQS00577.1 - 1.2e-08 34.4 10.7 5.9e-05 22.7 1.0 5.4 5 0 0 5 5 5 2 Tetratricopeptide repeat SAM_2 PF07647.17 OQS00577.1 - 1.2e-07 31.7 0.8 5.5e-06 26.4 0.8 2.8 1 1 0 1 1 1 1 SAM domain (Sterile alpha motif) TPR_8 PF13181.6 OQS00577.1 - 1.7e-06 27.7 8.4 0.0048 17.0 0.3 5.0 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_MalT PF17874.1 OQS00577.1 - 5.6e-06 25.9 1.9 1.1e-05 25.0 0.2 2.3 2 0 0 2 2 2 1 MalT-like TPR region KH_1 PF00013.29 OQS00577.1 - 8.9e-06 25.4 0.1 2.1e-05 24.3 0.1 1.6 1 0 0 1 1 1 1 KH domain SAM_1 PF00536.30 OQS00577.1 - 1.1e-05 25.8 0.1 0.026 15.0 0.0 2.7 2 0 0 2 2 2 2 SAM domain (Sterile alpha motif) TPR_7 PF13176.6 OQS00577.1 - 2e-05 24.3 14.6 0.089 12.9 0.4 6.6 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_2 PF07719.17 OQS00577.1 - 0.00016 21.5 12.0 0.01 15.9 1.0 5.6 6 0 0 6 6 5 1 Tetratricopeptide repeat AAA_16 PF13191.6 OQS00577.1 - 0.00072 20.0 1.9 0.00097 19.6 0.1 2.3 2 1 0 2 2 1 1 AAA ATPase domain TPR_16 PF13432.6 OQS00577.1 - 0.00095 19.8 0.6 0.22 12.2 0.0 3.4 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_17 PF13431.6 OQS00577.1 - 0.0021 18.3 7.4 5.8 7.5 0.1 5.5 5 0 0 5 5 5 1 Tetratricopeptide repeat NB-ARC PF00931.22 OQS00577.1 - 0.0022 17.2 0.0 0.0079 15.4 0.0 1.9 2 1 0 2 2 2 1 NB-ARC domain RsgA_GTPase PF03193.16 OQS00577.1 - 0.0023 17.8 0.0 0.62 10.0 0.0 2.5 2 0 0 2 2 2 1 RsgA GTPase AAA_25 PF13481.6 OQS00577.1 - 0.0025 17.4 0.0 0.0062 16.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain TPR_14 PF13428.6 OQS00577.1 - 0.018 15.8 0.7 8.7 7.5 0.1 3.8 3 0 0 3 3 2 0 Tetratricopeptide repeat TPR_19 PF14559.6 OQS00577.1 - 0.023 15.2 5.9 0.36 11.4 0.5 3.5 3 1 1 4 4 3 0 Tetratricopeptide repeat SHNi-TPR PF10516.9 OQS00577.1 - 0.11 12.0 6.0 2.5 7.6 0.1 4.5 5 0 0 5 5 5 0 SHNi-TPR AAA_22 PF13401.6 OQS00577.1 - 0.12 12.7 0.0 0.6 10.4 0.0 2.3 1 1 0 1 1 1 0 AAA domain KH_2 PF07650.17 OQS00577.1 - 0.14 12.0 0.1 0.41 10.5 0.1 1.7 1 0 0 1 1 1 0 KH domain TPR_11 PF13414.6 OQS00577.1 - 7 6.4 8.3 20 4.9 0.5 4.1 3 1 1 4 4 4 0 TPR repeat TackOD1 PF18551.1 OQS00578.1 - 0.00062 19.5 0.5 0.0011 18.7 0.5 1.3 1 0 0 1 1 1 1 Thaumarchaeal output domain 1 GrpE PF01025.19 OQS00578.1 - 0.0027 17.4 0.1 0.0067 16.1 0.1 1.6 1 0 0 1 1 1 1 GrpE zf_C2H2_ZHX PF18387.1 OQS00578.1 - 0.0034 17.0 0.0 0.0094 15.6 0.0 1.8 1 0 0 1 1 1 1 Zinc-fingers and homeoboxes C2H2 finger domain zf-Di19 PF05605.12 OQS00578.1 - 0.039 14.3 0.1 0.1 12.9 0.1 1.7 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding V-SNARE_C PF12352.8 OQS00578.1 - 0.057 13.7 1.9 1.1 9.6 0.1 2.5 2 0 0 2 2 2 0 Snare region anchored in the vesicle membrane C-terminus OMPdecase PF00215.24 OQS00578.1 - 0.065 12.8 0.2 0.21 11.1 0.0 1.8 1 1 1 2 2 2 0 Orotidine 5'-phosphate decarboxylase / HUMPS family Tox-REase-7 PF15649.6 OQS00578.1 - 0.1 12.9 0.4 0.28 11.5 0.1 1.9 2 0 0 2 2 2 0 Restriction endonuclease fold toxin 7 DUF2769 PF10967.8 OQS00578.1 - 0.15 12.8 0.3 3.9 8.2 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2769) DUF948 PF06103.11 OQS00578.1 - 0.18 12.1 5.1 5.8 7.2 0.1 2.5 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Sec20 PF03908.13 OQS00578.1 - 0.23 11.4 2.7 0.7 9.9 0.2 2.6 2 0 0 2 2 2 0 Sec20 DUF3854 PF12965.7 OQS00579.1 - 0.037 14.0 0.1 0.08 12.9 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3854) CoA_trans PF01144.23 OQS00580.1 - 1e-116 387.9 1.1 1.5e-75 253.4 0.1 2.0 2 0 0 2 2 2 2 Coenzyme A transferase LSM PF01423.22 OQS00581.1 - 9.4e-21 73.3 0.1 1.2e-20 73.0 0.1 1.1 1 0 0 1 1 1 1 LSM domain Peptidase_M16_M PF16187.5 OQS00581.1 - 0.021 14.1 0.1 0.024 13.9 0.1 1.0 1 0 0 1 1 1 0 Middle or third domain of peptidase_M16 DNA_pol3_tau_5 PF12170.8 OQS00581.1 - 0.031 14.3 0.1 0.036 14.1 0.1 1.1 1 0 0 1 1 1 0 DNA polymerase III tau subunit V interacting with alpha Fib_alpha PF08702.10 OQS00581.1 - 0.069 13.3 0.1 0.087 13.0 0.1 1.0 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family DUF16 PF01519.16 OQS00581.1 - 0.074 13.6 0.3 0.1 13.1 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function DUF16 Abhydrolase_1 PF00561.20 OQS00582.1 - 4.7e-07 29.7 0.0 1.3e-06 28.3 0.0 1.7 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_4 PF08386.10 OQS00582.1 - 0.00042 20.4 0.1 0.001 19.1 0.1 1.7 1 0 0 1 1 1 1 TAP-like protein Hydrolase_4 PF12146.8 OQS00582.1 - 0.0039 16.5 0.0 0.023 14.0 0.0 2.1 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Trp_oprn_chp PF09534.10 OQS00582.1 - 0.033 14.0 0.0 1.3 8.8 0.0 2.2 2 0 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) DUF2513 PF10711.9 OQS00582.1 - 0.083 13.2 0.1 0.33 11.3 0.1 2.1 1 1 0 1 1 1 0 Hypothetical protein (DUF2513) zf-RING_2 PF13639.6 OQS00583.1 - 1.8e-09 37.8 7.6 5.9e-09 36.1 7.1 2.1 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.7 OQS00583.1 - 7.3e-06 26.2 5.1 2.3e-05 24.6 5.1 1.9 1 1 0 1 1 1 1 RING-H2 zinc finger domain RINGv PF12906.7 OQS00583.1 - 5.7e-05 23.2 5.8 5.7e-05 23.2 5.8 1.9 2 0 0 2 2 2 1 RING-variant domain zf-ANAPC11 PF12861.7 OQS00583.1 - 0.002 18.2 1.4 0.0052 16.8 1.4 1.7 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.6 OQS00583.1 - 0.0031 17.3 6.8 0.011 15.5 6.8 2.0 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.8 OQS00583.1 - 0.028 14.6 7.6 0.14 12.4 7.6 2.1 1 1 0 1 1 1 0 FANCL C-terminal domain zf-C3HC4_2 PF13923.6 OQS00583.1 - 0.031 14.1 6.7 0.12 12.3 6.7 2.0 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DSPc PF00782.20 OQS00583.1 - 0.15 11.9 0.1 0.19 11.5 0.1 1.3 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain Baculo_RING PF05883.11 OQS00583.1 - 0.6 10.1 3.8 0.51 10.3 1.9 1.7 1 1 1 2 2 2 0 Baculovirus U-box/Ring-like domain zf-RING_5 PF14634.6 OQS00583.1 - 0.88 9.6 7.0 1 9.4 4.8 2.3 2 1 0 2 2 2 0 zinc-RING finger domain WT1 PF02165.15 OQS00584.1 - 0.017 14.4 0.0 0.017 14.4 0.0 1.2 1 0 0 1 1 1 0 Wilm's tumour protein FYVE_2 PF02318.16 OQS00584.1 - 0.023 14.9 0.5 0.038 14.2 0.1 1.6 2 0 0 2 2 2 0 FYVE-type zinc finger LLC1 PF14945.6 OQS00584.1 - 0.052 14.1 0.2 0.057 14.0 0.2 1.2 1 0 0 1 1 1 0 Normal lung function maintenance, Low in Lung Cancer 1 protein RabGAP-TBC PF00566.18 OQS00585.1 - 1.3e-22 80.5 0.5 1.9e-22 80.0 0.5 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain DUF3689 PF12463.8 OQS00586.1 - 2.2e-50 171.7 0.0 1.2e-49 169.3 0.0 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF3689) Whirly PF08536.11 OQS00586.1 - 0.097 12.5 0.0 0.19 11.6 0.0 1.3 1 0 0 1 1 1 0 Whirly transcription factor Globin PF00042.22 OQS00587.1 - 3.2e-05 24.4 0.0 0.00013 22.5 0.0 2.0 1 1 0 1 1 1 1 Globin DUF1487 PF07368.11 OQS00588.1 - 0.0062 16.0 0.1 0.051 13.0 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF1487) NIF PF03031.18 OQS00588.1 - 0.056 13.2 0.0 0.1 12.4 0.0 1.5 1 1 0 1 1 1 0 NLI interacting factor-like phosphatase HAD PF12710.7 OQS00588.1 - 0.18 12.2 0.0 6.5 7.1 0.0 2.2 1 1 1 2 2 2 0 haloacid dehalogenase-like hydrolase HSF_DNA-bind PF00447.17 OQS00589.1 - 4.2e-21 75.4 2.8 7.2e-21 74.6 2.8 1.4 1 0 0 1 1 1 1 HSF-type DNA-binding DUF1410 PF07198.11 OQS00589.1 - 0.074 13.6 0.4 0.16 12.5 0.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1410) cNMP_binding PF00027.29 OQS00590.1 - 6.8e-57 189.5 1.5 9.3e-17 60.9 0.0 5.1 5 0 0 5 5 5 4 Cyclic nucleotide-binding domain DUF3501 PF12007.8 OQS00590.1 - 0.072 13.1 0.0 0.2 11.6 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3501) IBN_N PF03810.19 OQS00591.1 - 1.3e-11 44.3 0.0 1.2e-09 37.9 0.0 2.7 2 0 0 2 2 2 1 Importin-beta N-terminal domain Cse1 PF08506.10 OQS00591.1 - 2.3e-08 33.3 0.2 1.5e-06 27.3 0.0 3.8 3 1 0 3 3 3 1 Cse1 HEAT_2 PF13646.6 OQS00591.1 - 0.065 13.6 0.3 12 6.4 0.0 3.7 3 0 0 3 3 3 0 HEAT repeats HEAT PF02985.22 OQS00591.1 - 0.07 13.4 4.2 0.52 10.7 0.0 4.6 5 0 0 5 5 5 0 HEAT repeat P_C10 PF14974.6 OQS00591.1 - 0.091 12.9 0.0 4.9 7.3 0.0 2.8 1 1 1 2 2 2 0 Protein C10 Vac14_Fab1_bd PF12755.7 OQS00591.1 - 0.12 12.9 1.8 3.7 8.2 0.0 3.9 4 1 1 5 5 5 0 Vacuolar 14 Fab1-binding region RTP1_C1 PF10363.9 OQS00591.1 - 0.14 12.3 0.8 0.87 9.8 0.1 2.9 2 1 0 2 2 2 0 Required for nuclear transport of RNA pol II C-terminus 1 Xpo1 PF08389.12 OQS00591.1 - 0.19 11.7 3.0 1.8 8.6 0.1 4.0 4 1 0 4 4 4 0 Exportin 1-like protein TBP PF00352.21 OQS00592.1 - 1.3e-56 188.5 0.0 5.6e-28 96.7 0.0 2.6 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) PH PF00169.29 OQS00592.1 - 3.3e-15 56.5 0.3 9.1e-15 55.1 0.3 1.8 1 0 0 1 1 1 1 PH domain DUF3378 PF11858.8 OQS00592.1 - 0.0029 17.7 0.0 1.4 9.1 0.0 2.5 2 0 0 2 2 2 2 Domain of unknown function (DUF3378) MIOX PF05153.15 OQS00593.1 - 1.4e-35 123.1 0.3 2.4e-35 122.3 0.3 1.3 1 0 0 1 1 1 1 Myo-inositol oxygenase Fascin PF06268.13 OQS00593.1 - 3.2e-06 27.3 0.0 3.6e-05 23.9 0.0 2.5 2 1 1 3 3 3 1 Fascin domain Acetyltransf_10 PF13673.7 OQS00593.1 - 0.0023 17.9 0.0 0.0042 17.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FRG1 PF06229.12 OQS00593.1 - 0.015 15.0 0.0 0.027 14.2 0.0 1.4 1 0 0 1 1 1 0 FRG1-like domain DUF569 PF04601.13 OQS00593.1 - 0.028 14.1 0.0 0.26 11.0 0.0 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF569) Acetyltransf_1 PF00583.25 OQS00593.1 - 0.078 13.2 0.0 0.16 12.3 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family SRP_SPB PF02978.19 OQS00594.1 - 1.2e-10 41.9 0.3 2.7e-10 40.7 0.1 1.6 2 0 0 2 2 2 1 Signal peptide binding domain WSD PF15613.6 OQS00594.1 - 0.14 12.6 1.6 0.25 11.9 1.6 1.7 1 1 0 1 1 1 0 Williams-Beuren syndrome DDT (WSD), D-TOX E motif GBP PF02263.19 OQS00640.1 - 3e-52 177.5 1.3 6.7e-41 140.3 0.1 2.2 2 0 0 2 2 2 2 Guanylate-binding protein, N-terminal domain AAA_16 PF13191.6 OQS00640.1 - 0.086 13.2 0.0 0.25 11.7 0.0 1.8 1 0 0 1 1 1 0 AAA ATPase domain UPF0020 PF01170.18 OQS00641.1 - 2.2e-11 43.8 0.1 1e-09 38.4 0.1 2.8 2 1 0 2 2 2 1 Putative RNA methylase family UPF0020 N6_N4_Mtase PF01555.18 OQS00641.1 - 8.2e-05 22.4 0.0 0.00074 19.3 0.0 2.2 2 0 0 2 2 2 1 DNA methylase MucB_RseB PF03888.14 OQS00641.1 - 0.02 14.5 0.0 0.039 13.5 0.0 1.4 1 0 0 1 1 1 0 MucB/RseB N-terminal domain N6-adenineMlase PF10237.9 OQS00641.1 - 0.068 13.0 0.0 0.13 12.1 0.0 1.5 1 0 0 1 1 1 0 Probable N6-adenine methyltransferase Methyltransf_11 PF08241.12 OQS00641.1 - 0.1 13.3 0.0 0.24 12.0 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain MethyltransfD12 PF02086.15 OQS00641.1 - 0.13 12.0 0.1 1.2 8.8 0.0 2.1 2 0 0 2 2 2 0 D12 class N6 adenine-specific DNA methyltransferase PhoLip_ATPase_C PF16212.5 OQS00642.1 - 2.1e-59 201.3 23.7 4.6e-58 196.9 23.7 2.2 1 1 0 1 1 1 1 Phospholipid-translocating P-type ATPase C-terminal MbeD_MobD PF04899.12 OQS00642.1 - 0.042 14.0 0.1 0.12 12.5 0.1 1.7 1 0 0 1 1 1 0 MbeD/MobD like GAPT PF11770.8 OQS00644.1 - 0.0033 17.3 0.2 0.0048 16.8 0.2 1.2 1 0 0 1 1 1 1 GRB2-binding adapter (GAPT) SKG6 PF08693.10 OQS00644.1 - 0.0065 15.9 0.2 0.014 14.8 0.2 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain TPR_21 PF09976.9 OQS00644.1 - 0.012 15.3 0.0 0.019 14.7 0.0 1.3 1 0 0 1 1 1 0 Tetratricopeptide repeat-like domain DUF4366 PF14283.6 OQS00644.1 - 0.018 15.1 0.6 0.13 12.3 0.1 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4366) Mem_trans PF03547.18 OQS00644.1 - 0.034 12.5 0.5 0.045 12.1 0.5 1.1 1 0 0 1 1 1 0 Membrane transport protein DUF4448 PF14610.6 OQS00644.1 - 0.04 13.7 0.7 0.12 12.2 0.1 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF4448) PTP_tm PF18861.1 OQS00644.1 - 0.042 13.9 0.0 0.074 13.0 0.0 1.3 1 0 0 1 1 1 0 Transmembrane domain of protein tyrosine phosphatase, receptor type J Adeno_E3_CR2 PF02439.15 OQS00644.1 - 0.042 13.6 0.0 0.097 12.5 0.0 1.5 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Nitrate_red_gam PF02665.14 OQS00644.1 - 0.062 12.8 0.0 0.082 12.4 0.0 1.3 1 0 0 1 1 1 0 Nitrate reductase gamma subunit DUF5305 PF17231.2 OQS00644.1 - 0.064 12.6 0.0 0.1 12.0 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5305) DUF4381 PF14316.6 OQS00644.1 - 0.11 12.7 0.0 0.18 12.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) DUF3149 PF11346.8 OQS00644.1 - 0.12 12.0 0.0 0.2 11.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3149) Pox_A14 PF05767.12 OQS00644.1 - 0.15 12.3 0.0 0.26 11.5 0.0 1.4 1 0 0 1 1 1 0 Poxvirus virion envelope protein A14 DUF2613 PF11021.8 OQS00644.1 - 0.32 11.1 3.5 1.6 8.9 3.5 2.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2613) Mito_carr PF00153.27 OQS00645.1 - 1.6e-25 88.8 4.9 2.7e-10 40.0 0.2 4.1 3 1 1 4 4 4 4 Mitochondrial carrier protein Curlin_rpt PF07012.12 OQS00645.1 - 0.019 15.0 0.2 0.056 13.5 0.2 1.8 1 0 0 1 1 1 0 Curlin associated repeat Gypsy PF07253.11 OQS00646.1 - 0.13 10.7 1.6 0.18 10.3 1.6 1.1 1 0 0 1 1 1 0 Gypsy protein Orf78 PF06024.12 OQS00647.1 - 0.051 13.9 0.1 0.1 12.9 0.1 1.4 1 0 0 1 1 1 0 Orf78 (ac78) TMEM154 PF15102.6 OQS00647.1 - 0.062 13.2 1.2 0.14 12.0 1.2 1.5 1 0 0 1 1 1 0 TMEM154 protein family RIFIN PF02009.16 OQS00647.1 - 0.075 12.9 0.1 0.11 12.3 0.1 1.2 1 0 0 1 1 1 0 Rifin Pox_EPC_I2-L1 PF12575.8 OQS00647.1 - 0.099 12.9 0.7 0.2 11.9 0.7 1.5 1 0 0 1 1 1 0 Poxvirus entry protein complex L1 and I2 DUF1180 PF06679.12 OQS00647.1 - 0.14 12.6 0.0 0.22 11.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) DUF3671 PF12420.8 OQS00647.1 - 0.14 12.2 1.4 0.29 11.2 1.4 1.5 1 0 0 1 1 1 0 Protein of unknown function Pkinase PF00069.25 OQS00648.1 - 8.7e-65 218.7 0.0 1.8e-64 217.7 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQS00648.1 - 1.2e-34 119.8 0.1 4e-34 118.1 0.0 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase UBA_4 PF14555.6 OQS00648.1 - 4.5e-05 23.2 0.0 0.028 14.2 0.0 2.6 2 0 0 2 2 2 2 UBA-like domain APH PF01636.23 OQS00648.1 - 0.00071 19.6 0.0 0.00071 19.6 0.0 3.5 2 1 0 3 3 3 1 Phosphotransferase enzyme family Pkinase_C PF00433.24 OQS00648.1 - 0.00094 19.8 0.2 0.0024 18.5 0.2 1.7 1 0 0 1 1 1 1 Protein kinase C terminal domain Na_Ca_ex PF01699.24 OQS00649.1 - 7e-25 87.7 30.3 4.1e-23 82.0 17.8 2.1 2 0 0 2 2 2 2 Sodium/calcium exchanger protein GNVR PF13807.6 OQS00650.1 - 0.013 15.4 0.0 0.021 14.7 0.0 1.3 1 0 0 1 1 1 0 G-rich domain on putative tyrosine kinase MHC2-interact PF09307.10 OQS00651.1 - 0.05 13.6 0.0 0.12 12.3 0.0 1.7 1 0 0 1 1 1 0 CLIP, MHC2 interacting FUSC PF04632.12 OQS00652.1 - 0.33 9.4 6.5 0.48 8.9 6.5 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family L31 PF09784.9 OQS00652.1 - 0.8 10.2 5.5 0.43 11.0 2.9 2.2 1 1 1 2 2 2 0 Mitochondrial ribosomal protein L31 Mito_carr PF00153.27 OQS00653.1 - 2.2e-28 98.0 2.8 7.8e-09 35.3 0.2 4.1 4 0 0 4 4 4 4 Mitochondrial carrier protein GAS PF13851.6 OQS00686.1 - 0.00083 18.8 5.3 0.00083 18.8 5.3 6.2 5 1 1 6 6 6 3 Growth-arrest specific micro-tubule binding SlyX PF04102.12 OQS00686.1 - 0.0072 16.9 3.4 0.0072 16.9 3.4 7.6 8 2 1 9 9 9 1 SlyX BST2 PF16716.5 OQS00686.1 - 0.02 15.4 11.0 0.02 15.4 11.0 7.5 5 3 2 7 7 7 0 Bone marrow stromal antigen 2 Osmo_CC PF08946.10 OQS00686.1 - 0.022 15.0 0.2 0.022 15.0 0.2 4.0 5 0 0 5 5 5 0 Osmosensory transporter coiled coil YflT PF11181.8 OQS00686.1 - 0.19 12.3 4.1 0.32 11.5 0.0 3.4 3 0 0 3 3 3 0 Heat induced stress protein YflT DUF3251 PF11622.8 OQS00686.1 - 0.51 10.0 12.9 0.016 14.8 4.8 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3251) Hist_deacetyl PF00850.19 OQS00688.1 - 5.8e-89 298.6 0.0 1e-88 297.8 0.0 1.4 1 1 0 1 1 1 1 Histone deacetylase domain PP2C PF00481.21 OQS00689.1 - 7.7e-71 238.7 0.2 9.6e-36 123.7 0.0 2.2 2 0 0 2 2 2 2 Protein phosphatase 2C UNC-50 PF05216.13 OQS00690.1 - 1.1e-34 120.0 12.4 1.3e-34 119.7 12.4 1.1 1 0 0 1 1 1 1 UNC-50 family UPF0126 PF03458.13 OQS00691.1 - 4.3e-37 125.8 20.7 6.1e-19 67.7 5.7 2.9 2 1 1 3 3 3 2 UPF0126 domain Vma12 PF11712.8 OQS00691.1 - 0.096 12.8 0.1 0.096 12.8 0.1 2.2 3 0 0 3 3 3 0 Endoplasmic reticulum-based factor for assembly of V-ATPase Lipase_3 PF01764.25 OQS00692.1 - 9e-33 113.1 0.0 1.4e-32 112.5 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) Cutinase PF01083.22 OQS00692.1 - 4.9e-07 29.9 0.0 9e-07 29.0 0.0 1.3 1 0 0 1 1 1 1 Cutinase DUF2974 PF11187.8 OQS00692.1 - 7.6e-06 25.6 0.1 0.0001 21.9 0.1 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF2974) Hydrolase_4 PF12146.8 OQS00692.1 - 1.4e-05 24.5 0.0 1.8e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Thioesterase PF00975.20 OQS00692.1 - 0.0012 19.0 0.0 0.0024 18.0 0.0 1.4 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_6 PF12697.7 OQS00692.1 - 0.016 15.8 0.0 0.021 15.4 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF676 PF05057.14 OQS00692.1 - 0.022 14.2 0.0 0.037 13.5 0.0 1.3 1 0 0 1 1 1 0 Putative serine esterase (DUF676) PGAP1 PF07819.13 OQS00692.1 - 0.066 12.9 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein UPF0126 PF03458.13 OQS00694.1 - 1.7e-36 123.9 11.4 2.1e-18 65.9 0.8 2.4 2 0 0 2 2 2 2 UPF0126 domain DUF3522 PF12036.8 OQS00695.1 - 1.3e-22 81.1 13.7 1.6e-22 80.7 10.3 2.7 2 1 0 2 2 2 1 Protein of unknown function (DUF3522) PPC PF04151.15 OQS00695.1 - 0.054 14.6 2.0 0.56 11.3 0.0 3.1 3 0 0 3 3 3 0 Bacterial pre-peptidase C-terminal domain fn3_3 PF14686.6 OQS00695.1 - 0.075 12.8 0.1 0.53 10.1 0.2 2.3 2 0 0 2 2 2 0 Polysaccharide lyase family 4, domain II Laminin_EGF PF00053.24 OQS00695.1 - 0.62 10.2 7.0 1.7 8.8 7.0 1.7 1 0 0 1 1 1 0 Laminin EGF domain EGF_2 PF07974.13 OQS00695.1 - 6.1 7.3 11.6 13 6.2 11.6 1.6 1 0 0 1 1 1 0 EGF-like domain Kinesin PF00225.23 OQS00696.1 - 6.3e-50 170.0 1.0 3.7e-49 167.4 0.1 2.4 2 1 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 OQS00696.1 - 2.7e-13 50.1 0.1 7.2e-13 48.7 0.0 1.6 2 0 0 2 2 2 1 Microtubule binding ATP-synt_ab PF00006.25 OQS00696.1 - 0.054 13.1 0.1 1.1 8.9 0.0 2.2 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain DSPc PF00782.20 OQS00697.1 - 1.1e-24 86.8 0.0 2.2e-24 85.7 0.0 1.6 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PRKCSH-like PF12999.7 OQS00697.1 - 1.3e-23 83.7 9.0 2.5e-23 82.8 9.0 1.4 1 0 0 1 1 1 1 Glucosidase II beta subunit-like Ldl_recept_a PF00057.18 OQS00697.1 - 0.0039 17.4 5.6 0.0039 17.4 5.6 3.0 3 0 0 3 3 3 1 Low-density lipoprotein receptor domain class A zf-C4H2 PF10146.9 OQS00697.1 - 0.036 14.4 0.2 0.036 14.4 0.2 1.9 2 0 0 2 2 2 0 Zinc finger-containing protein R3H PF01424.22 OQS00698.1 - 0.06 13.3 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 R3H domain WD40 PF00400.32 OQS00699.1 - 2.4e-16 59.8 5.6 0.00025 21.8 0.0 5.7 6 0 0 6 6 6 4 WD domain, G-beta repeat Nup160 PF11715.8 OQS00699.1 - 1.6e-06 27.1 0.5 0.0034 16.1 0.0 2.6 3 0 0 3 3 3 2 Nucleoporin Nup120/160 DAPDH_C PF16654.5 OQS00699.1 - 0.014 15.3 0.0 3.9 7.3 0.0 2.6 3 0 0 3 3 3 0 Diaminopimelic acid dehydrogenase C-terminal domain Phage_holin_7_1 PF16081.5 OQS00700.1 - 0.11 12.6 0.4 0.26 11.4 0.4 1.6 1 0 0 1 1 1 0 Mycobacterial 2 TMS Phage Holin (M2 Hol) Family FlxA PF14282.6 OQS00700.1 - 7.2 6.7 15.0 0.63 10.1 6.1 3.1 3 1 0 3 3 3 0 FlxA-like protein DUF4407 PF14362.6 OQS00700.1 - 8.9 5.6 10.1 6.6 6.0 0.1 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) ABC_tran PF00005.27 OQS00701.1 - 5.8e-11 43.1 0.0 7.9e-11 42.6 0.0 1.2 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 OQS00701.1 - 0.0002 20.9 0.1 0.00024 20.6 0.1 1.2 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain FKBP_N_2 PF18023.1 OQS00701.1 - 0.088 12.9 0.2 0.12 12.5 0.2 1.2 1 0 0 1 1 1 0 BDBT FKBP like N-terminal T3SS_needle_E PF08988.10 OQS00702.1 - 0.049 13.8 2.4 3.3 7.9 0.5 2.2 2 0 0 2 2 2 0 Type III secretion system, cytoplasmic E component of needle STAT_alpha PF01017.20 OQS00702.1 - 0.096 12.6 2.5 0.14 12.1 2.5 1.3 1 0 0 1 1 1 0 STAT protein, all-alpha domain CSD PF00313.22 OQS00703.1 - 4.6e-28 96.9 11.3 2.4e-09 36.9 0.0 7.4 7 0 0 7 7 7 5 'Cold-shock' DNA-binding domain CH PF00307.31 OQS00703.1 - 0.067 13.4 0.0 0.16 12.1 0.0 1.7 1 0 0 1 1 1 0 Calponin homology (CH) domain S1 PF00575.23 OQS00703.1 - 0.068 13.5 0.1 0.99 9.8 0.0 3.1 2 0 0 2 2 2 0 S1 RNA binding domain DUF2793 PF10983.8 OQS00703.1 - 0.08 12.8 0.1 0.44 10.5 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2793) p25-alpha PF05517.12 OQS00703.1 - 0.12 12.6 3.0 0.3 11.2 0.0 2.9 2 1 1 3 3 3 0 p25-alpha Rx_N PF18052.1 OQS00703.1 - 0.76 10.1 7.5 0.6 10.4 2.9 2.9 3 0 0 3 3 3 0 Rx N-terminal domain Spectrin PF00435.21 OQS00703.1 - 0.83 10.2 8.6 0.82 10.2 6.5 2.1 1 1 1 2 2 2 0 Spectrin repeat CusF_Ec PF11604.8 OQS00703.1 - 4.5 7.3 10.2 10 6.2 0.7 4.2 4 1 0 4 4 4 0 Copper binding periplasmic protein CusF Acyl-CoA_dh_1 PF00441.24 OQS00704.1 - 1.5e-49 168.0 4.0 1.5e-49 168.0 4.0 1.6 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 OQS00704.1 - 2.4e-37 128.1 0.2 7.9e-37 126.4 0.0 1.9 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 OQS00704.1 - 2.8e-24 85.9 2.8 4.4e-24 85.3 2.8 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 OQS00704.1 - 4.6e-23 81.2 0.1 8.9e-23 80.3 0.1 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain adh_short PF00106.25 OQS00705.1 - 4.3e-20 72.0 0.2 4.4e-10 39.3 0.0 2.4 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 OQS00705.1 - 5.6e-17 62.1 0.1 1.8e-10 40.8 0.1 2.3 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase VASt PF16016.5 OQS00706.1 - 4.2e-21 76.0 0.9 6.7e-21 75.3 0.9 1.3 1 0 0 1 1 1 1 VAD1 Analog of StAR-related lipid transfer domain DivIC PF04977.15 OQS00706.1 - 0.081 12.7 1.9 0.11 12.3 0.5 1.9 3 0 0 3 3 3 0 Septum formation initiator FGGY_N PF00370.21 OQS00707.1 - 5e-20 72.1 0.7 1.1e-19 71.0 0.7 1.5 1 1 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain BcrAD_BadFG PF01869.20 OQS00707.1 - 0.0021 17.6 0.0 0.005 16.4 0.1 1.4 1 1 0 1 1 1 1 BadF/BadG/BcrA/BcrD ATPase family DUF1190 PF06693.11 OQS00707.1 - 0.011 16.2 0.0 0.024 15.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1190) MutL PF13941.6 OQS00707.1 - 0.11 11.1 0.0 2.1 6.8 0.1 2.1 2 0 0 2 2 2 0 MutL protein PilM_2 PF11104.8 OQS00707.1 - 0.11 11.5 0.2 0.17 10.9 0.2 1.2 1 0 0 1 1 1 0 Type IV pilus assembly protein PilM; FliE PF02049.18 OQS00707.1 - 0.12 12.5 0.4 0.28 11.4 0.4 1.5 1 0 0 1 1 1 0 Flagellar hook-basal body complex protein FliE Bromodomain PF00439.25 OQS00708.1 - 4.7e-76 250.9 6.7 4.8e-19 68.2 0.1 6.8 6 1 0 6 6 6 6 Bromodomain SR-25 PF10500.9 OQS00708.1 - 0.0037 16.9 10.8 0.0037 16.9 10.8 4.1 5 1 0 5 5 5 1 Nuclear RNA-splicing-associated protein DEAD PF00270.29 OQS00720.1 - 5.3e-36 124.0 0.1 7.8e-36 123.5 0.1 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OQS00720.1 - 3.4e-28 98.2 0.0 2.6e-26 92.1 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 OQS00720.1 - 6.4e-05 23.0 0.0 0.00011 22.3 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit UTP25 PF06862.12 OQS00720.1 - 0.026 13.3 0.0 3.3 6.4 0.0 2.2 2 0 0 2 2 2 0 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 Cellulose_synt PF03552.14 OQS00721.1 - 2.1e-05 23.3 0.5 2.7e-05 22.9 0.5 1.2 1 0 0 1 1 1 1 Cellulose synthase Glyco_trans_2_3 PF13632.6 OQS00721.1 - 0.0037 17.2 0.1 0.0037 17.2 0.1 1.9 2 1 0 2 2 2 1 Glycosyl transferase family group 2 ResIII PF04851.15 OQS00722.1 - 1.2e-21 77.5 0.0 3.9e-21 75.8 0.0 1.9 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit zf-HC5HC2H_2 PF13832.6 OQS00722.1 - 3.9e-20 72.1 5.1 3.9e-20 72.1 5.1 3.4 3 0 0 3 3 3 1 PHD-zinc-finger like domain Helicase_C PF00271.31 OQS00722.1 - 5.6e-19 68.5 0.2 1.5e-18 67.2 0.2 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-HC5HC2H PF13771.6 OQS00722.1 - 2.1e-17 63.1 1.0 2.1e-17 63.1 1.0 4.4 3 1 1 4 4 4 1 PHD-like zinc-binding domain DEAD PF00270.29 OQS00722.1 - 5.6e-17 62.1 0.0 1e-15 57.9 0.0 2.5 2 0 0 2 2 2 1 DEAD/DEAH box helicase PHD_2 PF13831.6 OQS00722.1 - 3.1e-11 42.6 5.7 3.1e-11 42.6 5.7 4.4 4 0 0 4 4 4 1 PHD-finger ZZ PF00569.17 OQS00722.1 - 6.9e-10 38.6 10.5 6.9e-10 38.6 10.5 3.9 4 0 0 4 4 4 1 Zinc finger, ZZ type PHD PF00628.29 OQS00722.1 - 3.7e-07 29.9 9.7 3.7e-07 29.9 9.7 5.6 5 1 0 5 5 5 2 PHD-finger CALM_bind PF16025.5 OQS00722.1 - 0.023 15.1 4.2 0.13 12.8 4.2 2.4 1 0 0 1 1 1 0 Calcium-dependent calmodulin binding DUF3153 PF11353.8 OQS00722.1 - 0.77 9.3 0.0 0.77 9.3 0.0 3.9 4 1 0 4 4 4 0 Protein of unknown function (DUF3153) C1_2 PF03107.16 OQS00722.1 - 0.81 10.1 45.8 0.026 14.8 2.6 5.2 5 0 0 5 5 5 0 C1 domain zf-RanBP PF00641.18 OQS00722.1 - 2.1 7.7 19.0 0.01 15.2 3.6 3.6 3 0 0 3 3 3 0 Zn-finger in Ran binding protein and others LRR_8 PF13855.6 OQS00723.1 - 1.2e-39 133.8 55.0 1.9e-08 33.9 6.2 9.7 7 3 2 10 10 10 8 Leucine rich repeat LRR_4 PF12799.7 OQS00723.1 - 1.1e-27 95.5 57.0 3.8e-05 24.0 0.0 11.2 10 2 1 12 12 12 10 Leucine Rich repeats (2 copies) RsmF_methylt_CI PF17126.5 OQS00723.1 - 0.0037 17.3 0.3 0.67 10.0 0.0 4.3 3 1 1 4 4 4 1 RsmF rRNA methyltransferase first C-terminal domain LRR_1 PF00560.33 OQS00723.1 - 0.01 16.3 54.2 21 6.2 0.7 15.2 17 2 0 17 17 17 0 Leucine Rich Repeat Band_7 PF01145.25 OQS00723.1 - 1.3 9.0 4.1 0.61 10.1 0.9 2.1 2 0 0 2 2 2 0 SPFH domain / Band 7 family RNA_pol_Rpb1_5 PF04998.17 OQS00723.1 - 2.7 7.4 4.6 26 4.1 4.1 2.3 2 1 0 2 2 2 0 RNA polymerase Rpb1, domain 5 Pkinase PF00069.25 OQS00725.1 - 5.8e-43 147.2 0.0 1.2e-42 146.1 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQS00725.1 - 1e-27 97.1 0.0 2e-27 96.1 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OQS00725.1 - 8e-07 28.7 0.0 2e-06 27.4 0.0 1.7 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 OQS00725.1 - 4.8e-05 22.3 0.0 4.8e-05 22.3 0.0 1.9 2 0 0 2 2 2 1 Fungal protein kinase RXT2_N PF08595.11 OQS00725.1 - 2.7 8.0 15.7 0.23 11.5 5.2 3.2 3 0 0 3 3 3 0 RXT2-like, N-terminal MFS_1 PF07690.16 OQS00726.1 - 6.4e-16 58.2 13.3 6.8e-16 58.1 13.3 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 OQS00726.1 - 1.2e-09 37.6 9.5 1.4e-09 37.3 9.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.13 OQS00726.1 - 0.00063 18.3 2.1 0.00068 18.2 2.1 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Cyclin_N PF00134.23 OQS00727.1 - 1.3e-09 37.9 0.2 2.4e-09 37.0 0.2 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.11 OQS00727.1 - 1.3e-09 38.6 0.0 1.8e-09 38.2 0.0 1.2 1 0 0 1 1 1 1 Cyclin WW PF00397.26 OQS00727.1 - 1.8e-08 34.3 3.2 1.8e-08 34.3 3.2 2.1 2 0 0 2 2 2 1 WW domain Hs1pro-1_C PF07014.12 OQS00728.1 - 4.3e-09 36.2 0.1 9.8e-05 21.9 0.0 2.6 2 1 0 2 2 2 2 Hs1pro-1 protein C-terminus Trp_dioxygenase PF03301.13 OQS00728.1 - 6.5e-08 32.3 0.0 1.3e-07 31.3 0.0 1.5 1 0 0 1 1 1 1 Tryptophan 2,3-dioxygenase LIM PF00412.22 OQS00747.1 - 4.4e-20 71.7 31.4 1e-10 41.7 8.6 3.4 3 0 0 3 3 3 2 LIM domain zf-ACC PF17848.1 OQS00747.1 - 6.8 6.9 16.0 5 7.3 0.1 4.5 4 0 0 4 4 4 0 Acetyl-coA carboxylase zinc finger domain DUF2401 PF10287.9 OQS00748.1 - 5.1e-41 140.8 0.1 5.1e-41 140.8 0.1 2.3 2 0 0 2 2 2 1 Putative TOS1-like glycosyl hydrolase (DUF2401) PAN_4 PF14295.6 OQS00748.1 - 1.2e-14 54.0 33.1 7.6e-06 25.7 4.7 4.3 4 0 0 4 4 4 3 PAN domain PAN_1 PF00024.26 OQS00748.1 - 5.2e-10 39.1 20.8 0.002 18.1 3.4 3.5 2 1 1 3 3 3 3 PAN domain DUF2403 PF10290.9 OQS00748.1 - 5.1e-09 36.4 0.2 1.5e-08 34.9 0.2 1.9 1 0 0 1 1 1 1 Glycine-rich protein domain (DUF2403) PAN_3 PF08277.12 OQS00748.1 - 0.0009 19.0 22.9 0.015 15.1 3.1 3.6 3 0 0 3 3 3 2 PAN-like domain MANEC PF07502.14 OQS00748.1 - 9.1 6.6 22.7 4.6 7.6 0.7 3.6 2 1 1 3 3 3 0 MANEC domain ATE_C PF04377.15 OQS00749.1 - 2e-41 141.8 1.4 3.6e-41 140.9 1.4 1.4 1 0 0 1 1 1 1 Arginine-tRNA-protein transferase, C terminus ATE_N PF04376.13 OQS00749.1 - 5.5e-20 71.5 0.5 5.5e-20 71.5 0.5 2.5 3 0 0 3 3 3 1 Arginine-tRNA-protein transferase, N terminus Cluap1 PF10234.9 OQS00749.1 - 0.0035 16.8 3.4 0.0067 15.9 3.4 1.4 1 1 0 1 1 1 1 Clusterin-associated protein-1 PBP_like_2 PF12849.7 OQS00749.1 - 0.15 11.7 0.0 0.25 11.0 0.0 1.3 1 0 0 1 1 1 0 PBP superfamily domain TFX_C PF14601.6 OQS00750.1 - 0.031 14.2 0.2 0.11 12.5 0.2 1.8 1 1 0 1 1 1 0 DNA_binding protein, TFX, C-term AAA-ATPase_like PF09820.9 OQS00751.1 - 0.089 12.2 0.1 1 8.7 0.0 2.1 2 0 0 2 2 2 0 Predicted AAA-ATPase LIM PF00412.22 OQS00752.1 - 2.5e-10 40.4 2.7 3.3e-10 40.0 2.7 1.2 1 0 0 1 1 1 1 LIM domain KTI12 PF08433.10 OQS00753.1 - 1.2e-16 61.0 0.7 2.4e-16 60.0 0.7 1.4 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_33 PF13671.6 OQS00753.1 - 4.8e-10 39.8 0.0 1.7e-09 38.0 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 OQS00753.1 - 3.9e-05 23.9 1.2 0.00044 20.5 0.0 2.7 2 1 0 2 2 2 1 AAA domain Ubiquitin_4 PF18036.1 OQS00753.1 - 9.1e-05 22.4 0.2 0.00049 20.1 0.0 2.3 2 0 0 2 2 2 1 Ubiquitin-like domain AAA_18 PF13238.6 OQS00753.1 - 0.00085 19.9 0.0 0.0041 17.7 0.0 2.2 2 1 0 2 2 2 1 AAA domain AAA_17 PF13207.6 OQS00753.1 - 0.00085 19.8 0.0 0.004 17.6 0.0 2.0 2 1 0 2 2 2 1 AAA domain NB-ARC PF00931.22 OQS00753.1 - 0.006 15.8 0.0 0.014 14.6 0.0 1.7 1 0 0 1 1 1 1 NB-ARC domain ABC_tran PF00005.27 OQS00753.1 - 0.0082 16.7 1.1 0.08 13.5 1.1 2.5 1 1 0 1 1 1 1 ABC transporter APS_kinase PF01583.20 OQS00753.1 - 0.014 15.3 0.0 0.051 13.5 0.0 1.9 1 1 0 1 1 1 0 Adenylylsulphate kinase AAA PF00004.29 OQS00753.1 - 0.021 15.3 0.0 0.13 12.7 0.0 2.3 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 OQS00753.1 - 0.025 14.9 0.1 0.32 11.3 0.0 2.4 2 0 0 2 2 2 0 AAA ATPase domain Zeta_toxin PF06414.12 OQS00753.1 - 0.029 13.6 0.0 0.071 12.4 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin AAA_5 PF07728.14 OQS00753.1 - 0.032 14.2 0.0 0.17 11.8 0.0 2.4 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) DnaG_DnaB_bind PF08278.11 OQS00753.1 - 0.039 14.5 1.6 0.078 13.6 1.6 1.4 1 0 0 1 1 1 0 DNA primase DnaG DnaB-binding MMR_HSR1 PF01926.23 OQS00753.1 - 0.043 13.9 0.1 0.29 11.2 0.0 2.4 2 2 0 2 2 2 0 50S ribosome-binding GTPase CPT PF07931.12 OQS00753.1 - 0.076 12.9 0.0 0.2 11.5 0.0 1.7 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein RNA_helicase PF00910.22 OQS00753.1 - 0.088 13.2 2.3 0.15 12.5 0.3 2.6 3 1 0 3 3 1 0 RNA helicase PAN_2 PF08276.11 OQS00754.1 - 0.034 14.3 0.6 0.1 12.7 0.6 1.8 1 0 0 1 1 1 0 PAN-like domain WD40 PF00400.32 OQS00755.1 - 5.3e-45 150.5 13.1 2.2e-09 37.8 0.0 7.1 7 0 0 7 7 7 5 WD domain, G-beta repeat TFIID_NTD2 PF04494.15 OQS00755.1 - 4.2e-34 117.6 4.7 4.2e-34 117.6 4.7 1.7 2 0 0 2 2 2 1 WD40 associated region in TFIID subunit, NTD2 domain PhoD PF09423.10 OQS00755.1 - 9e-22 77.6 0.3 5.9e-21 74.9 0.2 2.3 2 1 0 2 2 2 1 PhoD-like phosphatase ANAPC4_WD40 PF12894.7 OQS00755.1 - 2.2e-07 31.1 0.2 0.22 11.9 0.0 4.9 4 1 2 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain Cytochrom_D1 PF02239.16 OQS00755.1 - 1.9e-06 26.7 0.2 4e-06 25.6 0.2 1.4 1 0 0 1 1 1 1 Cytochrome D1 heme domain Nup160 PF11715.8 OQS00755.1 - 0.00016 20.5 0.4 0.021 13.5 0.0 3.2 2 1 1 3 3 3 1 Nucleoporin Nup120/160 WD40_like PF17005.5 OQS00755.1 - 0.007 15.7 0.0 1.4 8.2 0.0 2.4 2 0 0 2 2 2 2 WD40-like domain eIF2A PF08662.11 OQS00755.1 - 0.027 14.4 0.3 0.46 10.3 0.0 2.8 2 1 0 3 3 3 0 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 OQS00755.1 - 0.1 11.5 0.1 1.9 7.4 0.0 2.8 1 1 3 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Takusan PF04822.13 OQS00756.1 - 2.2 8.2 7.5 0.22 11.4 1.7 2.1 2 1 0 2 2 2 0 Takusan FH2 PF02181.23 OQS00757.1 - 2.6e-30 105.8 0.0 9e-29 100.7 0.0 2.3 2 0 0 2 2 2 2 Formin Homology 2 Domain CCDC53 PF10152.9 OQS00757.1 - 6e-12 46.2 0.0 1.4e-11 45.1 0.0 1.7 2 0 0 2 2 2 1 Subunit CCDC53 of WASH complex Octopine_DH PF02317.17 OQS00793.1 - 9.9e-38 129.6 0.0 1.4e-37 129.1 0.0 1.2 1 0 0 1 1 1 1 NAD/NADP octopine/nopaline dehydrogenase, alpha-helical domain ApbA PF02558.16 OQS00793.1 - 0.0001 22.0 0.0 0.00017 21.3 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA IlvN PF07991.12 OQS00793.1 - 0.00057 19.5 0.1 0.0025 17.4 0.1 1.8 1 1 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain F420_oxidored PF03807.17 OQS00793.1 - 0.00094 19.7 0.0 0.0021 18.6 0.0 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent PDH PF02153.17 OQS00793.1 - 0.0015 17.6 0.0 0.0028 16.7 0.0 1.4 1 0 0 1 1 1 1 Prephenate dehydrogenase NAD_Gly3P_dh_N PF01210.23 OQS00793.1 - 0.0022 18.0 0.0 0.0035 17.3 0.0 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus YjeF_N PF03853.15 OQS00793.1 - 0.0033 17.3 0.0 0.0052 16.7 0.0 1.3 1 0 0 1 1 1 1 YjeF-related protein N-terminus Pyr_redox PF00070.27 OQS00793.1 - 0.0075 16.8 0.1 0.02 15.4 0.1 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 OQS00793.1 - 0.0097 15.2 0.1 0.016 14.5 0.1 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 OQS00793.1 - 0.082 12.2 0.0 0.13 11.5 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 OQS00793.1 - 0.18 11.0 0.1 0.26 10.5 0.1 1.2 1 0 0 1 1 1 0 FAD binding domain MSC PF09402.10 OQS00794.1 - 4.1e-13 49.5 4.4 4.1e-13 49.5 4.4 3.1 1 1 2 3 3 3 1 Man1-Src1p-C-terminal domain Zip PF02535.22 OQS00795.1 - 9.7e-26 90.8 9.4 2.3e-25 89.6 9.4 1.6 1 0 0 1 1 1 1 ZIP Zinc transporter Cu-oxidase_3 PF07732.15 OQS00795.1 - 1.3e-11 44.5 1.9 2.7e-07 30.6 0.1 3.8 4 0 0 4 4 4 2 Multicopper oxidase Cu-oxidase_2 PF07731.14 OQS00795.1 - 7.7e-11 41.9 4.9 2.5e-10 40.2 4.9 1.9 1 1 0 1 1 1 1 Multicopper oxidase Bacillus_HBL PF05791.11 OQS00796.1 - 0.014 15.3 0.4 0.051 13.4 0.1 1.9 2 0 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) Snapin_Pallidin PF14712.6 OQS00796.1 - 3.4 8.2 11.3 0.99 9.9 1.8 3.3 3 1 1 4 4 4 0 Snapin/Pallidin Kinesin PF00225.23 OQS00797.1 - 1.8e-96 323.0 0.6 4.2e-95 318.5 0.6 2.2 1 1 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 OQS00797.1 - 9.4e-25 87.3 0.4 2.3e-24 86.1 0.1 1.8 2 0 0 2 2 2 1 Microtubule binding Katanin_con80 PF13925.6 OQS00797.1 - 0.11 12.5 0.1 5.8 6.9 0.0 3.1 3 0 0 3 3 3 0 con80 domain of Katanin Ank_2 PF12796.7 OQS00798.1 - 3e-29 101.4 14.6 6.6e-12 45.8 1.9 2.5 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQS00798.1 - 2.5e-21 75.7 0.2 2.2e-11 44.0 0.1 3.7 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 OQS00798.1 - 5.2e-16 58.5 2.6 1.5e-05 25.2 0.0 4.2 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 OQS00798.1 - 2.4e-15 56.2 2.5 0.00041 20.7 0.1 4.7 4 0 0 4 4 4 3 Ankyrin repeat Ank_3 PF13606.6 OQS00798.1 - 2.6e-15 55.0 2.7 0.00051 20.3 0.1 5.5 5 0 0 5 5 5 3 Ankyrin repeat HTH_Tnp_Tc5 PF03221.16 OQS00798.1 - 5.8e-12 45.5 0.1 1.1e-11 44.5 0.1 1.5 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain MOLO1 PF17175.4 OQS00798.1 - 0.086 13.0 0.6 7.2 6.8 0.0 2.6 2 0 0 2 2 2 0 Modulator of levamisole receptor-1 HOCHOB PF17943.1 OQS00799.1 - 0.025 15.3 0.1 0.075 13.7 0.1 1.8 1 0 0 1 1 1 0 Homeobox-cysteine loop-homeobox Ephrin_rec_like PF07699.13 OQS00808.1 - 3e-10 39.7 110.2 0.01 15.6 2.7 11.8 3 3 7 11 11 11 10 Putative ephrin-receptor like NCD3G PF07562.14 OQS00808.1 - 2.1e-06 27.6 77.5 0.00096 19.1 2.2 11.2 3 2 9 13 13 13 9 Nine Cysteines Domain of family 3 GPCR Tyrosinase PF00264.20 OQS00810.1 - 5.6e-22 79.1 1.0 3.1e-21 76.7 0.1 2.1 2 0 0 2 2 2 1 Common central domain of tyrosinase Tyrosinase PF00264.20 OQS00811.1 - 3.3e-22 79.9 0.1 7.2e-22 78.8 0.1 1.5 1 0 0 1 1 1 1 Common central domain of tyrosinase CBM_35 PF16990.5 OQS00811.1 - 0.024 14.9 0.2 1.7 8.9 0.0 2.8 3 0 0 3 3 3 0 Carbohydrate binding module (family 35) Lipase_3 PF01764.25 OQS00812.1 - 3.4e-27 95.1 0.0 8.7e-27 93.7 0.0 1.8 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 OQS00812.1 - 0.0044 17.6 0.0 0.008 16.8 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF2974 PF11187.8 OQS00812.1 - 0.013 15.1 0.0 0.58 9.7 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2974) Abhydrolase_3 PF07859.13 OQS00812.1 - 0.067 13.0 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold DUF1129 PF06570.11 OQS00812.1 - 0.27 10.7 4.8 0.097 12.1 1.6 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) Mannosyl_trans3 PF11051.8 OQS00814.1 - 1.2e-32 113.3 0.0 8e-32 110.7 0.0 2.0 1 1 0 1 1 1 1 Mannosyltransferase putative E3_UbLigase_RBR PF18091.1 OQS00814.1 - 0.24 11.6 0.5 1.2 9.3 0.1 2.2 2 1 0 2 2 2 0 E3 Ubiquitin Ligase RBR C-terminal domain E7 PF00527.18 OQS00815.1 - 0.54 10.5 4.0 0.54 10.5 2.9 1.6 1 1 0 1 1 1 0 E7 protein, Early protein U3_snoRNA_assoc PF08297.11 OQS00815.1 - 1.4 9.7 10.8 0.13 13.0 3.6 2.6 2 1 0 2 2 2 0 U3 snoRNA associated DNA_pol_B PF00136.21 OQS00816.1 - 3.7e-114 382.0 0.1 5.7e-114 381.3 0.1 1.3 1 0 0 1 1 1 1 DNA polymerase family B zf-DNA_Pol PF08996.10 OQS00816.1 - 4.8e-46 156.9 2.7 1e-45 155.8 2.7 1.5 1 0 0 1 1 1 1 DNA Polymerase alpha zinc finger DNA_pol_B_exo1 PF03104.19 OQS00816.1 - 6.7e-34 117.5 0.0 1.2e-33 116.7 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_alpha_N PF12254.8 OQS00816.1 - 1.8e-17 63.1 6.0 8.9e-17 60.9 6.0 2.3 1 0 0 1 1 1 1 DNA polymerase alpha subunit p180 N terminal DNA_pol_B_2 PF03175.13 OQS00816.1 - 0.015 14.2 0.0 0.032 13.1 0.0 1.5 1 0 0 1 1 1 0 DNA polymerase type B, organellar and viral Mucin_bdg PF03272.13 OQS00816.1 - 0.082 12.9 0.3 0.29 11.2 0.0 2.1 2 0 0 2 2 2 0 Putative mucin or carbohydrate-binding module Ribosomal_L32e PF01655.18 OQS00817.1 - 7.8e-51 171.0 1.8 9.3e-51 170.8 1.8 1.1 1 0 0 1 1 1 1 Ribosomal protein L32 CDO_I PF05995.12 OQS00826.1 - 1.9e-27 95.7 0.0 3.6e-27 94.8 0.0 1.4 1 0 0 1 1 1 1 Cysteine dioxygenase type I DOT1 PF08123.13 OQS00826.1 - 4.7e-18 65.5 0.1 1.2e-17 64.1 0.0 1.6 2 0 0 2 2 2 1 Histone methylation protein DOT1 Metallophos PF00149.28 OQS00826.1 - 4.4e-13 50.2 0.4 9.2e-13 49.1 0.4 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase PCO_ADO PF07847.12 OQS00826.1 - 0.084 12.3 0.0 0.21 11.0 0.0 1.6 1 1 0 1 1 1 0 PCO_ADO Methyltransf_25 PF13649.6 OQS00826.1 - 0.12 13.1 0.0 9.3 7.0 0.0 2.9 3 0 0 3 3 3 0 Methyltransferase domain Methyltransf_31 PF13847.6 OQS00826.1 - 0.17 11.7 0.1 0.53 10.1 0.1 1.9 1 1 0 1 1 1 0 Methyltransferase domain DUF974 PF06159.13 OQS00827.1 - 4.6e-51 174.0 0.4 1.4e-50 172.4 0.0 2.1 3 0 0 3 3 3 1 Protein of unknown function (DUF974) FHA PF00498.26 OQS00827.1 - 3e-07 30.7 0.1 0.045 14.1 0.0 3.6 3 0 0 3 3 3 3 FHA domain Yop-YscD_cpl PF16697.5 OQS00827.1 - 1.8e-06 28.2 0.0 0.63 10.4 0.0 4.3 4 0 0 4 4 4 2 Inner membrane component of T3SS, cytoplasmic domain Trs65 PF12735.7 OQS00827.1 - 0.00087 18.8 2.1 0.15 11.4 0.0 3.4 3 1 1 4 4 4 2 TRAPP trafficking subunit Trs65 Transglut_C PF00927.22 OQS00827.1 - 0.001 19.2 0.1 0.0023 18.0 0.1 1.6 1 0 0 1 1 1 1 Transglutaminase family, C-terminal ig like domain cNMP_binding PF00027.29 OQS00827.1 - 0.0024 17.9 0.0 0.0047 17.0 0.0 1.5 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain CDO_I PF05995.12 OQS00828.1 - 2.4e-30 105.1 0.0 3e-30 104.8 0.0 1.2 1 0 0 1 1 1 1 Cysteine dioxygenase type I PCO_ADO PF07847.12 OQS00828.1 - 0.00079 18.9 0.2 0.0096 15.4 0.2 2.3 1 1 0 1 1 1 1 PCO_ADO Peptidase_M32 PF02074.15 OQS00828.1 - 0.04 12.7 0.2 0.045 12.5 0.2 1.1 1 0 0 1 1 1 0 Carboxypeptidase Taq (M32) metallopeptidase DUF2205 PF10224.9 OQS00828.1 - 0.049 13.6 0.5 0.089 12.8 0.5 1.5 1 0 0 1 1 1 0 Short coiled-coil protein Pro_isomerase PF00160.21 OQS00829.1 - 3.7e-47 160.5 0.2 3.7e-47 160.5 0.2 1.5 2 0 0 2 2 2 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD TFB6 PF17110.5 OQS00829.1 - 0.0068 16.2 1.0 0.011 15.5 1.0 1.3 1 0 0 1 1 1 1 Subunit 11 of the general transcription factor TFIIH CDC45 PF02724.14 OQS00829.1 - 0.011 14.0 15.0 0.012 13.9 15.0 1.0 1 0 0 1 1 1 0 CDC45-like protein DUF913 PF06025.12 OQS00829.1 - 0.079 11.9 5.5 0.11 11.5 5.5 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) DUF3438 PF11920.8 OQS00829.1 - 0.46 9.7 4.1 0.44 9.7 3.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3438) Rtf2 PF04641.12 OQS00829.1 - 1.2 8.4 13.8 1.9 7.8 13.8 1.2 1 0 0 1 1 1 0 Rtf2 RING-finger OAD_gamma PF04277.13 OQS00829.1 - 1.8 9.2 6.4 3.1 8.5 6.4 1.3 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain Macoilin PF09726.9 OQS00829.1 - 4.7 5.6 15.9 5.5 5.4 15.9 1.0 1 0 0 1 1 1 0 Macoilin family SRP-alpha_N PF04086.13 OQS00829.1 - 7.4 6.4 24.2 10 5.9 24.2 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal RR_TM4-6 PF06459.12 OQS00829.1 - 9.6 5.9 11.7 13 5.5 11.7 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 ABC_tran PF00005.27 OQS00830.1 - 3.1e-25 89.3 0.6 1.9e-20 73.8 0.1 3.4 2 1 0 2 2 2 2 ABC transporter AAA_29 PF13555.6 OQS00830.1 - 0.041 13.6 0.6 0.077 12.8 0.0 1.7 2 0 0 2 2 2 0 P-loop containing region of AAA domain DUF3712 PF12505.8 OQS00831.1 - 2e-20 73.3 9.4 2.2e-12 47.3 1.1 3.7 3 0 0 3 3 3 3 Protein of unknown function (DUF3712) Pkinase_Tyr PF07714.17 OQS00832.1 - 3.8e-17 62.4 0.2 2.6e-09 36.8 0.3 2.5 1 1 1 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 OQS00832.1 - 2.1e-07 30.6 0.5 1.4e-05 24.6 0.3 2.1 1 1 1 2 2 2 2 Protein kinase domain Kdo PF06293.14 OQS00832.1 - 0.00078 18.9 0.8 0.0013 18.1 0.8 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family ABC_tran PF00005.27 OQS00833.1 - 8.7e-06 26.3 0.1 1.6e-05 25.4 0.1 1.4 1 0 0 1 1 1 1 ABC transporter SPRY PF00622.28 OQS00833.1 - 0.00016 21.8 0.0 0.00025 21.1 0.0 1.2 1 0 0 1 1 1 1 SPRY domain AAA_29 PF13555.6 OQS00833.1 - 0.014 15.1 0.0 0.025 14.3 0.0 1.3 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_21 PF13304.6 OQS00833.1 - 0.094 12.5 0.3 0.18 11.6 0.3 1.4 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 OQS00833.1 - 0.13 12.7 0.1 0.22 12.0 0.1 1.3 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 OQS00833.1 - 0.15 11.9 0.0 0.2 11.5 0.0 1.3 1 0 0 1 1 1 0 RsgA GTPase cobW PF02492.19 OQS00833.1 - 0.15 11.6 0.3 0.24 11.0 0.3 1.2 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain ENTH PF01417.20 OQS00871.1 - 8.4e-12 45.2 0.0 1.4e-11 44.5 0.0 1.3 1 0 0 1 1 1 1 ENTH domain CDC24_OB2 PF17245.2 OQS00873.1 - 8.3e-19 68.4 0.1 1.6e-18 67.5 0.1 1.4 1 0 0 1 1 1 1 Cell division control protein 24, OB domain 2 CDC24_OB1 PF17246.2 OQS00873.1 - 4.2e-08 33.3 0.0 1e-07 32.1 0.0 1.6 1 0 0 1 1 1 1 Cell division control protein 24, OB domain 1 Rep_fac-A_C PF08646.10 OQS00873.1 - 0.0032 17.2 0.8 0.0059 16.4 0.8 1.3 1 0 0 1 1 1 1 Replication factor-A C terminal domain zf-3CxxC PF13695.6 OQS00873.1 - 0.034 14.6 0.2 0.071 13.6 0.2 1.5 1 0 0 1 1 1 0 Zinc-binding domain ORC2 PF04084.14 OQS00874.1 - 2.4e-56 191.1 0.0 3.3e-56 190.6 0.0 1.1 1 0 0 1 1 1 1 Origin recognition complex subunit 2 RCC1 PF00415.18 OQS00875.1 - 7.3e-58 193.0 13.3 2.2e-12 47.4 0.3 7.6 7 0 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 OQS00875.1 - 1.1e-29 101.5 29.5 4.1e-05 23.2 2.5 6.7 6 0 0 6 6 6 6 Regulator of chromosome condensation (RCC1) repeat eIF3_p135 PF12807.7 OQS00875.1 - 0.00063 19.8 0.3 0.0028 17.7 0.0 2.1 2 0 0 2 2 2 1 Translation initiation factor eIF3 subunit 135 CLU PF13236.6 OQS00875.1 - 0.065 13.1 0.2 0.14 12.0 0.2 1.6 1 0 0 1 1 1 0 Clustered mitochondria ELMO_CED12 PF04727.13 OQS00876.1 - 1.1e-27 97.2 0.0 3.7e-27 95.6 0.0 1.9 2 1 0 2 2 2 1 ELMO/CED-12 family PH PF00169.29 OQS00876.1 - 9.1e-19 67.9 0.3 2.8e-16 59.9 0.0 3.0 3 0 0 3 3 3 1 PH domain PH_11 PF15413.6 OQS00876.1 - 0.001 19.5 0.4 0.0098 16.3 0.2 2.7 2 1 0 2 2 2 1 Pleckstrin homology domain PH_9 PF15410.6 OQS00876.1 - 0.12 12.7 0.0 0.4 11.0 0.0 1.8 2 0 0 2 2 2 0 Pleckstrin homology domain IRS PF02174.17 OQS00876.1 - 0.12 12.2 0.0 0.74 9.7 0.0 2.1 2 0 0 2 2 2 0 PTB domain (IRS-1 type) Aminotran_5 PF00266.19 OQS00877.1 - 2.3e-15 56.5 0.0 3.1e-14 52.7 0.0 2.0 1 1 0 1 1 1 1 Aminotransferase class-V PT PF04886.12 OQS00878.1 - 0.0045 16.5 58.4 0.0098 15.4 25.2 4.0 3 1 1 4 4 4 3 PT repeat DUF4203 PF13886.6 OQS00879.1 - 0.00013 21.7 3.6 0.00016 21.4 3.6 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4203) DUF2755 PF10954.8 OQS00879.1 - 0.14 12.1 1.9 0.17 11.8 0.9 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2755) Amnionless PF14828.6 OQS00879.1 - 0.19 10.6 0.1 0.2 10.5 0.1 1.0 1 0 0 1 1 1 0 Amnionless Glyco_hydro_18 PF00704.28 OQS00880.1 - 2.4e-26 93.2 0.0 2.3e-25 90.0 0.0 2.3 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 Tetraspanin PF00335.20 OQS00881.1 - 1.3e-16 61.1 12.0 1.8e-16 60.6 12.0 1.2 1 0 0 1 1 1 1 Tetraspanin family DUF4199 PF13858.6 OQS00881.1 - 0.0037 17.7 2.3 0.0037 17.7 0.2 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF4199) ICE2 PF08426.10 OQS00881.1 - 0.032 13.3 0.7 0.057 12.5 0.7 1.3 1 0 0 1 1 1 0 ICE2 CobD_Cbib PF03186.13 OQS00881.1 - 0.041 13.1 0.0 0.093 11.9 0.0 1.6 1 1 0 1 1 1 0 CobD/Cbib protein Gram_pos_anchor PF00746.21 OQS00881.1 - 0.54 10.3 5.8 9 6.3 0.1 2.5 2 0 0 2 2 2 0 LPXTG cell wall anchor motif DUF4203 PF13886.6 OQS00882.1 - 6.9e-44 149.9 29.5 1.1e-43 149.3 29.5 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4203) Trp_oprn_chp PF09534.10 OQS00882.1 - 2.3 8.0 11.0 1.6 8.5 0.4 2.7 2 2 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) DUF2757 PF10955.8 OQS00883.1 - 0.062 13.6 0.1 0.46 10.8 0.0 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF2757) SHMT PF00464.19 OQS00929.1 - 7.4e-175 581.3 0.0 8.8e-175 581.1 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Beta_elim_lyase PF01212.21 OQS00929.1 - 0.00052 19.4 0.0 0.00096 18.5 0.0 1.5 1 1 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.21 OQS00929.1 - 0.00053 19.3 0.0 0.0011 18.3 0.0 1.5 1 1 0 1 1 1 1 Aminotransferase class I and II ERM PF00769.19 OQS00930.1 - 0.075 12.8 17.4 0.15 11.8 17.4 1.4 1 0 0 1 1 1 0 Ezrin/radixin/moesin family Mit_KHE1 PF10173.9 OQS00930.1 - 0.79 9.8 3.2 2.4 8.2 3.2 1.8 1 0 0 1 1 1 0 Mitochondrial K+-H+ exchange-related Fzo_mitofusin PF04799.13 OQS00930.1 - 0.87 9.1 8.9 2.3 7.8 8.9 1.7 1 0 0 1 1 1 0 fzo-like conserved region MCU PF04678.13 OQS00930.1 - 1.4 9.0 4.4 3 7.9 4.4 1.6 1 0 0 1 1 1 0 Mitochondrial calcium uniporter TCP PF03634.13 OQS00930.1 - 2.6 8.6 12.0 2.7 8.5 8.5 2.1 2 0 0 2 2 2 0 TCP family transcription factor DUF747 PF05346.11 OQS00931.1 - 1.1e-83 281.4 21.4 1.6e-83 280.8 21.4 1.2 1 0 0 1 1 1 1 Eukaryotic membrane protein family Sigma_M_inh PF17453.2 OQS00931.1 - 0.031 14.7 1.7 0.031 14.7 1.7 2.8 3 0 0 3 3 3 0 Sigma-M inhibitor DUF3685 PF12452.8 OQS00932.1 - 0.027 14.2 0.7 0.049 13.3 0.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3685) Baculo_PEP_C PF04513.12 OQS00932.1 - 0.044 13.8 3.4 2.2 8.3 0.6 2.5 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Fib_alpha PF08702.10 OQS00932.1 - 0.99 9.6 8.9 3 8.0 2.4 2.8 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family LPP PF04728.13 OQS00932.1 - 1.1 9.7 4.2 30 5.1 1.2 2.8 2 1 0 2 2 2 0 Lipoprotein leucine-zipper Cluap1 PF10234.9 OQS00932.1 - 1.3 8.4 10.2 0.14 11.5 2.9 2.1 1 1 0 2 2 2 0 Clusterin-associated protein-1 Polysacc_deac_1 PF01522.21 OQS00933.1 - 8.4e-11 41.8 0.0 1.4e-10 41.2 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase CLASP_N PF12348.8 OQS00934.1 - 1.3e-10 41.2 0.1 1.8e-10 40.8 0.1 1.1 1 0 0 1 1 1 1 CLASP N terminal DUF3395 PF11875.8 OQS00935.1 - 1.1e-27 96.8 0.0 1.6e-27 96.3 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3395) DnaJ PF00226.31 OQS00935.1 - 2.4e-14 53.2 0.1 4.1e-14 52.4 0.1 1.4 1 0 0 1 1 1 1 DnaJ domain DHHC PF01529.20 OQS00936.1 - 1e-27 96.8 12.4 1e-27 96.8 12.4 2.3 2 0 0 2 2 2 1 DHHC palmitoyltransferase LRR_6 PF13516.6 OQS00936.1 - 5.9e-05 22.8 0.1 0.0046 16.9 0.0 2.9 2 0 0 2 2 2 1 Leucine Rich repeat TetR_C_34 PF17929.1 OQS00936.1 - 6.6 6.9 7.0 6.7 6.8 0.2 3.5 3 0 0 3 3 3 0 Tetracyclin repressor-like, C-terminal domain PALP PF00291.25 OQS00937.1 - 1.4e-64 218.3 0.0 1.8e-64 218.0 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme CBS PF00571.28 OQS00937.1 - 8.2e-14 51.8 0.1 1.2e-06 28.8 0.0 3.0 3 0 0 3 3 3 2 CBS domain DAGK_cat PF00781.24 OQS00937.1 - 0.047 13.3 0.0 0.099 12.3 0.0 1.5 1 0 0 1 1 1 0 Diacylglycerol kinase catalytic domain FYVE PF01363.21 OQS00939.1 - 6.3e-17 61.5 7.4 1.5e-16 60.3 7.4 1.6 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.16 OQS00939.1 - 1.6 9.0 11.5 0.11 12.7 6.1 1.9 2 0 0 2 2 2 0 FYVE-type zinc finger NOB1_Zn_bind PF08772.11 OQS00939.1 - 3.5 7.9 8.1 11 6.3 6.9 2.4 2 0 0 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like Solute_trans_a PF03619.16 OQS00940.1 - 9.8e-74 248.2 18.9 1.1e-73 248.0 18.9 1.0 1 0 0 1 1 1 1 Organic solute transporter Ostalpha CDRT4 PF15213.6 OQS00940.1 - 0.22 12.1 0.0 0.4 11.3 0.0 1.3 1 0 0 1 1 1 0 CMT1A duplicated region transcript 4 protein ArfGap PF01412.18 OQS00941.1 - 3.2e-42 143.3 0.2 4.7e-42 142.8 0.2 1.2 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf Fibrillarin PF01269.17 OQS00976.1 - 7e-105 349.2 0.0 8.7e-105 348.9 0.0 1.0 1 0 0 1 1 1 1 Fibrillarin GCD14 PF08704.10 OQS00976.1 - 0.00024 20.8 0.0 0.00039 20.2 0.0 1.3 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit PCMT PF01135.19 OQS00976.1 - 0.0084 15.9 0.0 0.012 15.3 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Ribosomal_L21p PF00829.21 OQS00977.1 - 5.2e-31 106.9 2.0 6.4e-31 106.6 2.0 1.1 1 0 0 1 1 1 1 Ribosomal prokaryotic L21 protein Use1 PF09753.9 OQS00978.1 - 0.011 15.5 1.1 0.013 15.3 1.1 1.0 1 0 0 1 1 1 0 Membrane fusion protein Use1 RNA_pol_A_bac PF01000.26 OQS00979.1 - 1.9e-29 102.3 0.0 4e-29 101.2 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.24 OQS00979.1 - 8.2e-24 82.8 0.0 1.2e-23 82.3 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Fer4_9 PF13187.6 OQS00979.1 - 0.06 13.5 1.9 0.17 12.1 1.9 1.7 1 0 0 1 1 1 0 4Fe-4S dicluster domain Fer4_7 PF12838.7 OQS00979.1 - 0.21 12.2 2.4 0.59 10.8 2.4 1.8 1 0 0 1 1 1 0 4Fe-4S dicluster domain Cpn60_TCP1 PF00118.24 OQS00980.1 - 4.6e-21 75.0 0.7 1.8e-20 73.1 0.7 1.8 1 1 0 1 1 1 1 TCP-1/cpn60 chaperonin family Sds3 PF08598.11 OQS00982.1 - 0.0021 18.1 5.4 0.0038 17.3 5.4 1.3 1 1 0 1 1 1 1 Sds3-like VASP_tetra PF08776.11 OQS00982.1 - 0.051 13.2 0.2 0.099 12.2 0.2 1.4 1 0 0 1 1 1 0 VASP tetramerisation domain DSBA PF01323.20 OQS00983.1 - 2.3e-21 76.5 0.0 2.7e-21 76.2 0.0 1.1 1 0 0 1 1 1 1 DSBA-like thioredoxin domain Thioredoxin_4 PF13462.6 OQS00983.1 - 0.022 14.9 0.0 0.026 14.7 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin AA_permease PF00324.21 OQS00984.1 - 1.2e-35 123.1 41.7 1.6e-35 122.6 41.7 1.2 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 OQS00984.1 - 1.1e-32 113.4 43.6 1.1e-32 113.4 42.9 1.3 1 1 0 1 1 1 1 Amino acid permease Wzy_C_2 PF11846.8 OQS00984.1 - 0.33 10.9 6.8 1.6 8.6 0.2 2.8 2 0 0 2 2 2 0 Virulence factor membrane-bound polymerase, C-terminal NEMP PF10225.9 OQS00984.1 - 0.34 10.5 7.7 1.1 8.8 2.9 2.4 2 0 0 2 2 2 0 NEMP family AdoHcyase PF05221.17 OQS00985.1 - 1.5e-143 477.4 0.0 1.7e-143 477.2 0.0 1.0 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD PF00670.21 OQS00985.1 - 8.9e-83 276.2 2.6 1.3e-82 275.6 2.6 1.3 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.19 OQS00985.1 - 7.2e-09 35.3 0.4 1.2e-08 34.5 0.4 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.12 OQS00985.1 - 0.00026 20.6 0.3 0.00049 19.7 0.3 1.5 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain TrkA_N PF02254.18 OQS00985.1 - 0.0014 18.9 0.6 0.0068 16.7 0.6 2.1 1 1 0 1 1 1 1 TrkA-N domain THF_DHG_CYH_C PF02882.19 OQS00985.1 - 0.015 14.6 2.1 0.07 12.5 2.1 1.9 1 1 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Shikimate_DH PF01488.20 OQS00985.1 - 0.024 14.7 0.5 0.062 13.4 0.5 1.6 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase ELFV_dehydrog PF00208.21 OQS00985.1 - 0.026 14.2 0.1 0.045 13.5 0.1 1.4 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Peptidase_S74 PF13884.6 OQS01008.1 - 1.2e-09 38.4 0.9 2.1e-09 37.6 0.9 1.4 1 0 0 1 1 1 1 Chaperone of endosialidase DUF2917 PF11142.8 OQS01008.1 - 0.014 14.7 1.7 31 4.0 0.0 6.0 5 0 0 5 5 5 0 Protein of unknown function (DUF2917) LBP_BPI_CETP PF01273.25 OQS01008.1 - 7.6 6.1 19.1 0.078 12.6 0.3 6.2 5 0 0 5 5 5 0 LBP / BPI / CETP family, N-terminal domain zf-RING_2 PF13639.6 OQS01010.1 - 5.5e-13 49.0 6.9 1.1e-12 48.1 6.9 1.5 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 OQS01010.1 - 1.4e-07 31.7 7.8 4e-07 30.2 7.8 1.8 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 OQS01010.1 - 1.5e-07 31.2 5.7 2.6e-07 30.5 5.7 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 OQS01010.1 - 1.8e-06 27.9 2.7 1.8e-06 27.9 2.7 1.6 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4 PF00097.25 OQS01010.1 - 8.7e-06 25.5 6.5 1.8e-05 24.5 6.5 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.8 OQS01010.1 - 1.1e-05 25.5 4.8 8.2e-05 22.7 4.8 2.2 1 1 0 1 1 1 1 FANCL C-terminal domain zf-RING_UBOX PF13445.6 OQS01010.1 - 1.1e-05 25.3 7.4 1.1e-05 25.3 7.4 1.9 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_11 PF17123.5 OQS01010.1 - 3.5e-05 23.5 6.1 3.5e-05 23.5 6.1 2.3 2 0 0 2 2 2 1 RING-like zinc finger Prok-RING_4 PF14447.6 OQS01010.1 - 3.6e-05 23.5 5.6 0.00022 21.0 5.5 2.3 2 1 0 2 2 2 1 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 OQS01010.1 - 4.7e-05 23.2 9.1 0.00016 21.4 9.1 2.0 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 OQS01010.1 - 0.00012 21.9 5.1 0.00029 20.6 5.1 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 OQS01010.1 - 0.0029 17.2 8.3 0.0059 16.2 7.3 2.0 1 1 1 2 2 2 1 Zinc-ribbon, C4HC2 type zf-Nse PF11789.8 OQS01010.1 - 0.0044 16.8 5.9 0.1 12.5 4.6 2.6 2 1 0 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit PX PF00787.24 OQS01010.1 - 0.0046 16.9 0.0 0.008 16.1 0.0 1.3 1 0 0 1 1 1 1 PX domain RINGv PF12906.7 OQS01010.1 - 0.28 11.3 7.7 0.76 10.0 7.1 2.0 1 1 1 2 2 2 0 RING-variant domain Prok-RING_1 PF14446.6 OQS01010.1 - 2.6 8.0 6.7 6.9 6.7 2.6 2.7 2 1 1 3 3 3 0 Prokaryotic RING finger family 1 zf-RING_2 PF13639.6 OQS01011.1 - 8e-23 80.5 21.2 3.2e-13 49.8 2.6 3.0 2 1 0 2 2 2 2 Ring finger domain zf-rbx1 PF12678.7 OQS01011.1 - 7.5e-15 55.0 20.5 2.9e-07 30.6 5.7 2.9 2 1 0 2 2 2 2 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 OQS01011.1 - 7.1e-13 48.3 10.7 1.9e-07 31.0 0.2 4.2 3 2 2 5 5 5 2 RING-type zinc-finger zf-C3HC4_2 PF13923.6 OQS01011.1 - 1.9e-12 46.8 24.7 3.7e-08 33.1 4.5 3.3 3 2 0 3 3 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OQS01011.1 - 2.9e-11 43.1 19.9 7.1e-07 29.1 3.7 2.9 2 1 1 3 3 3 2 zinc-RING finger domain zf-RING_11 PF17123.5 OQS01011.1 - 1.1e-10 41.0 20.6 1.9e-06 27.5 1.0 3.7 4 0 0 4 4 4 2 RING-like zinc finger zf-ANAPC11 PF12861.7 OQS01011.1 - 1.3e-10 41.2 11.9 9.8e-06 25.5 1.3 2.9 2 0 0 2 2 2 2 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4 PF00097.25 OQS01011.1 - 1.3e-10 40.9 19.9 1.5e-05 24.8 2.1 3.0 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 OQS01011.1 - 3.7e-09 36.3 16.6 0.0001 22.1 3.7 2.8 2 1 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) PX PF00787.24 OQS01011.1 - 2.3e-08 34.0 1.7 0.0001 22.3 1.0 2.6 2 0 0 2 2 2 2 PX domain Prok-RING_4 PF14447.6 OQS01011.1 - 2.8e-07 30.3 22.3 0.00017 21.3 4.7 3.4 3 1 1 4 4 3 2 Prokaryotic RING finger family 4 FANCL_C PF11793.8 OQS01011.1 - 1.5e-06 28.3 15.1 0.00082 19.5 2.3 3.8 2 2 0 2 2 2 2 FANCL C-terminal domain Zn_ribbon_17 PF17120.5 OQS01011.1 - 0.00048 19.7 24.8 0.0051 16.4 5.2 3.2 3 1 0 3 3 3 2 Zinc-ribbon, C4HC2 type zf-Nse PF11789.8 OQS01011.1 - 0.00083 19.1 12.4 0.048 13.5 1.4 4.1 4 1 1 5 5 4 2 Zinc-finger of the MIZ type in Nse subunit RINGv PF12906.7 OQS01011.1 - 0.003 17.6 17.0 0.21 11.8 6.0 3.1 2 1 0 2 2 2 2 RING-variant domain zf-C3H2C3 PF17122.5 OQS01011.1 - 0.011 15.7 1.7 0.011 15.7 1.7 3.6 2 1 1 3 3 3 0 Zinc-finger zf-RING_4 PF14570.6 OQS01011.1 - 0.24 11.2 14.9 1.3 8.8 1.5 3.5 3 0 0 3 3 3 0 RING/Ubox like zinc-binding domain Prok-RING_1 PF14446.6 OQS01011.1 - 0.68 9.9 22.2 0.27 11.2 2.5 5.0 3 2 2 5 5 5 0 Prokaryotic RING finger family 1 zf-RING_6 PF14835.6 OQS01011.1 - 2.2 8.2 13.2 1 9.3 0.6 3.3 2 1 0 2 2 2 0 zf-RING of BARD1-type protein zf-RING_10 PF16685.5 OQS01011.1 - 8.3 6.6 15.2 0.2 11.8 2.8 3.0 2 1 1 3 3 3 0 zinc RING finger of MSL2 IBR PF01485.21 OQS01012.1 - 4.9e-07 29.9 11.0 4.9e-07 29.9 11.0 2.9 2 1 1 3 3 3 2 IBR domain, a half RING-finger domain zf-piccolo PF05715.13 OQS01012.1 - 0.36 11.0 19.5 0.49 10.6 6.1 2.6 2 0 0 2 2 2 0 Piccolo Zn-finger FYVE PF01363.21 OQS01012.1 - 3.2 7.9 23.9 4 7.7 9.2 2.4 2 0 0 2 2 2 0 FYVE zinc finger DUF2464 PF10240.9 OQS01013.1 - 0.05 13.2 1.1 0.057 13.0 1.1 1.1 1 0 0 1 1 1 0 Multivesicular body subunit 12 MDD_C PF18376.1 OQS01013.1 - 0.058 13.1 0.5 0.084 12.6 0.5 1.3 1 1 0 1 1 1 0 Mevalonate 5-diphosphate decarboxylase C-terminal domain IBR PF01485.21 OQS01015.1 - 3.9e-17 62.2 44.0 1.8e-10 40.9 5.1 3.4 2 1 1 3 3 3 3 IBR domain, a half RING-finger domain zf-B_box PF00643.24 OQS01015.1 - 8.3 6.7 39.0 0.46 10.7 2.6 4.6 3 1 1 4 4 4 0 B-box zinc finger Zip PF02535.22 OQS01016.1 - 7.1e-41 140.5 23.1 7e-40 137.3 23.1 1.9 1 1 0 1 1 1 1 ZIP Zinc transporter HupE_UreJ PF04955.12 OQS01016.1 - 1.2 8.5 9.7 0.28 10.7 5.4 2.1 2 0 0 2 2 2 0 HupE / UreJ protein 7tm_7 PF08395.12 OQS01016.1 - 9.6 5.3 15.4 0.47 9.6 0.7 3.0 3 1 1 4 4 4 0 7tm Chemosensory receptor Insulin_TMD PF17870.1 OQS01017.1 - 0.28 11.3 4.1 0.35 11.0 3.2 1.7 1 1 0 1 1 1 0 Insulin receptor trans-membrane segment JmjC PF02373.22 OQS01047.1 - 5.6e-36 123.4 1.8 2.5e-35 121.3 2.0 2.0 2 0 0 2 2 2 1 JmjC domain, hydroxylase JmjN PF02375.17 OQS01047.1 - 5.7e-15 55.0 1.6 1.6e-14 53.5 1.6 1.8 1 0 0 1 1 1 1 jmjN domain zf-C5HC2 PF02928.16 OQS01047.1 - 1.6e-08 34.8 6.4 1.6e-08 34.8 6.4 2.1 2 0 0 2 2 2 1 C5HC2 zinc finger Mito_carr PF00153.27 OQS01049.1 - 4.8e-65 215.5 0.5 9e-21 73.6 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_7 PF13499.6 OQS01049.1 - 2.1e-14 53.7 1.8 3.8e-08 33.7 0.1 2.7 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_1 PF00036.32 OQS01049.1 - 6e-10 37.9 6.0 0.00015 21.1 0.0 4.6 5 0 0 5 5 5 3 EF hand EF-hand_6 PF13405.6 OQS01049.1 - 3.4e-09 35.9 4.3 0.001 18.8 0.0 4.4 5 0 0 5 5 5 2 EF-hand domain EF-hand_8 PF13833.6 OQS01049.1 - 8e-07 28.8 5.6 0.0012 18.6 0.0 4.5 2 1 3 5 5 5 2 EF-hand domain pair EF-hand_5 PF13202.6 OQS01049.1 - 0.0019 17.6 1.5 0.15 11.6 0.0 3.4 3 0 0 3 3 3 1 EF hand EF-hand_9 PF14658.6 OQS01049.1 - 0.091 13.1 0.0 0.4 11.1 0.0 2.0 2 0 0 2 2 2 0 EF-hand domain Serine_protease PF18405.1 OQS01049.1 - 0.24 10.5 1.9 6.6 5.8 0.0 3.1 3 1 0 3 3 3 0 Gammaproteobacterial serine protease LemA PF04011.12 OQS01050.1 - 0.034 14.0 0.7 0.092 12.6 0.7 1.7 1 0 0 1 1 1 0 LemA family Peptidase_A17 PF05380.13 OQS01050.1 - 0.079 13.0 1.2 0.2 11.7 1.2 1.6 1 0 0 1 1 1 0 Pao retrotransposon peptidase Hydrolase_4 PF12146.8 OQS01051.1 - 9.3e-48 162.6 0.0 1.1e-47 162.4 0.0 1.0 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 OQS01051.1 - 2e-08 34.2 0.2 6.4e-08 32.6 0.2 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 OQS01051.1 - 1.2e-06 29.3 0.0 1.6e-06 28.9 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 OQS01051.1 - 0.00021 20.8 0.0 0.0012 18.3 0.0 2.1 2 1 0 2 2 2 1 Prolyl oligopeptidase family TPR_1 PF00515.28 OQS01052.1 - 1.1e-53 177.0 18.6 3.9e-07 29.6 0.0 12.0 12 0 0 12 12 12 10 Tetratricopeptide repeat TPR_2 PF07719.17 OQS01052.1 - 4.8e-53 173.1 12.7 1.5e-05 24.7 0.2 12.5 12 1 0 12 12 12 10 Tetratricopeptide repeat TPR_8 PF13181.6 OQS01052.1 - 7.9e-47 153.6 8.5 0.00041 20.3 0.1 12.1 12 0 0 12 12 12 9 Tetratricopeptide repeat TPR_17 PF13431.6 OQS01052.1 - 1.6e-31 106.4 26.2 4e-05 23.7 0.0 10.5 11 0 0 11 11 10 7 Tetratricopeptide repeat TPR_11 PF13414.6 OQS01052.1 - 1.5e-23 82.2 26.2 5.5e-07 29.2 0.1 9.8 6 4 4 10 10 10 4 TPR repeat TPR_12 PF13424.6 OQS01052.1 - 2.4e-23 82.2 14.7 0.00016 21.9 0.1 8.3 6 4 2 8 8 8 7 Tetratricopeptide repeat TPR_14 PF13428.6 OQS01052.1 - 1.1e-22 78.8 9.1 0.0016 19.1 0.0 10.4 7 2 3 10 10 10 5 Tetratricopeptide repeat TPR_19 PF14559.6 OQS01052.1 - 6.7e-22 77.8 12.7 2.3e-09 37.6 0.0 8.1 5 2 3 9 9 9 4 Tetratricopeptide repeat TPR_6 PF13174.6 OQS01052.1 - 4.5e-19 67.7 12.7 0.23 12.2 0.0 12.0 12 0 0 12 12 12 4 Tetratricopeptide repeat TPR_16 PF13432.6 OQS01052.1 - 1.6e-17 63.9 8.0 4.7e-05 23.9 0.0 7.2 4 2 3 7 7 7 5 Tetratricopeptide repeat TPR_7 PF13176.6 OQS01052.1 - 2.8e-15 55.1 12.5 0.0054 16.7 0.0 9.1 10 0 0 10 10 10 4 Tetratricopeptide repeat TPR_9 PF13371.6 OQS01052.1 - 7.1e-14 51.7 9.9 0.0075 16.4 0.0 6.4 4 1 2 6 6 6 4 Tetratricopeptide repeat TPR_15 PF13429.6 OQS01052.1 - 1.8e-09 37.3 8.7 0.00098 18.4 0.4 4.1 2 1 2 4 4 4 3 Tetratricopeptide repeat ChAPs PF09295.10 OQS01052.1 - 4.2e-07 29.3 1.4 0.0051 15.9 0.0 4.4 3 1 2 5 5 5 2 ChAPs (Chs5p-Arf1p-binding proteins) ANAPC3 PF12895.7 OQS01052.1 - 7.4e-07 29.3 16.1 1.2e-05 25.4 0.5 4.0 3 2 2 5 5 4 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_21 PF09976.9 OQS01052.1 - 1.3e-06 28.2 8.8 0.74 9.5 0.0 5.6 3 1 2 5 5 5 1 Tetratricopeptide repeat-like domain TPR_MalT PF17874.1 OQS01052.1 - 5.1e-05 22.8 0.6 0.00044 19.7 0.0 2.7 2 1 0 2 2 2 1 MalT-like TPR region TPR_20 PF14561.6 OQS01052.1 - 0.00076 19.8 3.2 1.3 9.4 0.0 4.8 4 1 1 5 5 5 1 Tetratricopeptide repeat Sda PF08970.10 OQS01052.1 - 0.0045 16.7 1.6 11 5.9 0.1 3.8 3 0 0 3 3 3 0 Sporulation inhibitor A BTAD PF03704.17 OQS01052.1 - 0.017 15.5 4.0 0.13 12.7 0.1 3.4 2 2 3 5 5 4 0 Bacterial transcriptional activator domain PHM7_cyt PF14703.6 OQS01052.1 - 0.03 14.5 0.0 5.9 7.1 0.0 3.6 4 1 1 5 5 5 0 Cytosolic domain of 10TM putative phosphate transporter nos_propeller PF18764.1 OQS01052.1 - 0.085 12.8 0.0 78 3.3 0.0 3.4 3 0 0 3 3 3 0 Nitrous oxide reductase propeller repeat EST1_DNA_bind PF10373.9 OQS01052.1 - 0.32 10.4 2.5 1.9 7.9 0.0 2.5 3 0 0 3 3 3 0 Est1 DNA/RNA binding domain TPR_10 PF13374.6 OQS01052.1 - 0.94 9.4 18.2 12 5.9 0.0 7.3 8 0 0 8 8 8 0 Tetratricopeptide repeat Peptidase_M15_4 PF13539.6 OQS01052.1 - 1.7 9.2 3.4 76 3.9 0.1 3.3 3 0 0 3 3 3 0 D-alanyl-D-alanine carboxypeptidase Y_phosphatase PF00102.27 OQS01055.1 - 1.2e-61 208.3 0.0 1.6e-61 207.9 0.0 1.0 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.20 OQS01055.1 - 0.00023 21.0 0.2 0.0011 18.8 0.2 1.9 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 OQS01055.1 - 0.059 13.3 0.0 0.096 12.6 0.0 1.4 1 0 0 1 1 1 0 Tyrosine phosphatase family PTPlike_phytase PF14566.6 OQS01055.1 - 0.064 13.4 0.0 0.13 12.4 0.0 1.6 1 0 0 1 1 1 0 Inositol hexakisphosphate Cpn60_TCP1 PF00118.24 OQS01056.1 - 2.8e-20 72.4 0.0 4e-20 71.9 0.0 1.2 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family EXS PF03124.14 OQS01066.1 - 1e-63 215.7 10.4 1e-63 215.7 10.4 1.4 2 0 0 2 2 2 1 EXS family LRR_4 PF12799.7 OQS01066.1 - 2.1e-06 27.9 0.5 3.9 8.0 0.0 4.3 4 0 0 4 4 4 3 Leucine Rich repeats (2 copies) F-box PF00646.33 OQS01066.1 - 0.03 14.2 0.3 0.11 12.4 0.3 2.0 1 0 0 1 1 1 0 F-box domain LRR_6 PF13516.6 OQS01066.1 - 0.069 13.2 0.1 15 6.0 0.0 4.0 4 0 0 4 4 4 0 Leucine Rich repeat LRR_1 PF00560.33 OQS01066.1 - 1.2 10.0 3.3 84 4.3 0.0 4.9 5 0 0 5 5 5 0 Leucine Rich Repeat CopD PF05425.13 OQS01066.1 - 2.2 8.7 4.7 46 4.5 2.4 3.3 3 0 0 3 3 3 0 Copper resistance protein D LSM PF01423.22 OQS01067.1 - 2.9e-19 68.5 0.8 3.7e-19 68.2 0.8 1.1 1 0 0 1 1 1 1 LSM domain BPL_C PF02237.17 OQS01067.1 - 0.0073 16.2 0.5 0.015 15.2 0.5 1.5 1 0 0 1 1 1 1 Biotin protein ligase C terminal domain SM-ATX PF14438.6 OQS01067.1 - 0.064 13.4 0.2 0.092 12.9 0.2 1.2 1 0 0 1 1 1 0 Ataxin 2 SM domain Peptidase_C54 PF03416.19 OQS01068.1 - 1.4e-81 274.0 0.0 2.3e-81 273.3 0.0 1.3 1 0 0 1 1 1 1 Peptidase family C54 LRR_4 PF12799.7 OQS01068.1 - 5.3e-10 39.4 8.8 6.5e-05 23.2 1.5 3.6 1 1 1 3 3 3 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 OQS01068.1 - 4.5e-06 26.3 3.7 4.5e-06 26.3 3.7 2.2 3 0 0 3 3 3 1 Leucine rich repeat LRR_9 PF14580.6 OQS01068.1 - 2.5e-05 23.8 1.8 4.8e-05 22.9 1.8 1.4 1 0 0 1 1 1 1 Leucine-rich repeat Peptidase_C78 PF07910.13 OQS01068.1 - 0.15 11.5 0.1 0.46 9.9 0.0 1.8 2 0 0 2 2 2 0 Peptidase family C78 LRR_1 PF00560.33 OQS01068.1 - 1.2 9.9 5.6 43 5.2 0.1 4.1 2 1 0 2 2 2 0 Leucine Rich Repeat GBP PF02263.19 OQS01069.1 - 2.9e-70 236.5 0.0 3.4e-70 236.3 0.0 1.0 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain GBP_C PF02841.14 OQS01069.1 - 1.4e-08 34.5 0.1 2.1e-08 33.9 0.1 1.3 1 0 0 1 1 1 1 Guanylate-binding protein, C-terminal domain RHD3 PF05879.12 OQS01069.1 - 0.02 13.1 0.0 0.033 12.4 0.0 1.3 1 0 0 1 1 1 0 Root hair defective 3 GTP-binding protein (RHD3) MMR_HSR1 PF01926.23 OQS01069.1 - 0.043 13.9 0.0 0.11 12.6 0.0 1.7 2 0 0 2 2 2 0 50S ribosome-binding GTPase MAPKK1_Int PF08923.10 OQS01070.1 - 6.7e-18 64.6 0.0 1.1e-17 64.0 0.0 1.3 1 0 0 1 1 1 1 Mitogen-activated protein kinase kinase 1 interacting MRP-S23 PF10484.9 OQS01070.1 - 0.0053 17.0 0.7 0.057 13.7 0.7 2.2 1 1 0 1 1 1 1 Mitochondrial ribosomal protein S23 Homeobox_KN PF05920.11 OQS01071.1 - 1.7e-14 53.4 1.5 3.6e-14 52.4 1.1 1.8 1 1 0 1 1 1 1 Homeobox KN domain Homeodomain PF00046.29 OQS01071.1 - 3e-09 36.6 1.0 7e-09 35.4 1.0 1.6 1 0 0 1 1 1 1 Homeodomain RRM_1 PF00076.22 OQS01072.1 - 0.014 15.2 0.0 0.027 14.3 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) efThoc1 PF11957.8 OQS01073.1 - 6.5e-89 298.8 0.6 1.1e-88 298.1 0.6 1.3 1 0 0 1 1 1 1 THO complex subunit 1 transcription elongation factor Gag_p12 PF01141.18 OQS01073.1 - 0.19 12.1 3.8 0.51 10.7 3.8 1.7 1 0 0 1 1 1 0 Gag polyprotein, inner coat protein p12 Spindle_Spc25 PF08234.12 OQS01074.1 - 7.4e-21 74.1 2.8 2.5e-20 72.5 2.8 1.9 1 0 0 1 1 1 1 Chromosome segregation protein Spc25 Spc24 PF08286.11 OQS01074.1 - 0.0011 19.1 2.0 0.0011 19.1 2.0 2.4 1 1 1 2 2 2 1 Spc24 subunit of Ndc80 BRE1 PF08647.11 OQS01074.1 - 0.12 12.4 15.2 0.11 12.6 13.3 2.0 1 1 0 1 1 1 0 BRE1 E3 ubiquitin ligase AAA_13 PF13166.6 OQS01074.1 - 0.16 10.6 13.6 0.067 11.8 10.9 1.6 1 1 1 2 2 2 0 AAA domain APG6_N PF17675.1 OQS01074.1 - 0.51 10.9 21.7 1.4 9.5 21.7 1.8 1 1 0 1 1 1 0 Apg6 coiled-coil region ACCA PF03255.14 OQS01074.1 - 0.77 9.6 11.3 3.2 7.6 7.5 2.2 1 1 1 2 2 2 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit Membralin PF09746.9 OQS01074.1 - 1.3 8.0 5.0 1.8 7.6 5.0 1.1 1 0 0 1 1 1 0 Tumour-associated protein DUF3450 PF11932.8 OQS01074.1 - 4.2 6.6 15.2 0.8 9.0 11.7 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) ALMT PF11744.8 OQS01074.1 - 8.6 5.1 7.9 11 4.7 7.9 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter Tmemb_185A PF10269.9 OQS01075.1 - 0.0066 16.2 9.2 0.0066 16.2 9.2 2.6 1 1 0 2 2 2 2 Transmembrane Fragile-X-F protein tRNA_m1G_MT PF01746.21 OQS01076.1 - 6.5e-08 32.5 0.0 1.6e-07 31.2 0.0 1.6 1 0 0 1 1 1 1 tRNA (Guanine-1)-methyltransferase Exo_endo_phos PF03372.23 OQS01076.1 - 0.0011 18.5 0.0 0.0028 17.2 0.0 1.7 2 0 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family Connexin PF00029.19 OQS01076.1 - 0.04 13.7 1.4 0.077 12.8 1.4 1.4 1 0 0 1 1 1 0 Connexin Vpu PF00558.19 OQS01076.1 - 0.054 13.3 0.6 0.16 11.8 0.6 1.8 1 0 0 1 1 1 0 Vpu protein Myb_DNA-binding PF00249.31 OQS01128.1 - 5.7e-19 68.0 0.1 5e-08 33.0 0.0 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OQS01128.1 - 0.00017 21.8 3.6 0.1 12.9 0.3 2.8 2 0 0 2 2 2 2 Myb-like DNA-binding domain Dimeth_Pyl PF09505.10 OQS01128.1 - 0.0071 14.9 0.0 1.2 7.6 0.0 2.1 2 0 0 2 2 2 2 Dimethylamine methyltransferase (Dimeth_PyL) Asp_Glu_race PF01177.22 OQS01128.1 - 0.023 14.5 0.7 0.15 11.8 0.1 2.0 2 0 0 2 2 2 0 Asp/Glu/Hydantoin racemase Importin_rep PF18773.1 OQS01128.1 - 0.04 13.6 0.3 2.3 8.0 0.0 2.7 3 0 0 3 3 3 0 Importin 13 repeat PaREP1 PF05942.11 OQS01128.1 - 0.29 11.1 3.4 0.4 10.6 0.4 2.3 2 0 0 2 2 2 0 Archaeal PaREP1/PaREP8 family UCR_hinge PF02320.16 OQS01128.1 - 0.57 10.4 5.1 11 6.4 0.7 2.5 2 0 0 2 2 2 0 Ubiquinol-cytochrome C reductase hinge protein DUF1002 PF06207.11 OQS01128.1 - 0.61 9.6 6.9 0.23 10.9 1.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1002) Myb_DNA-binding PF00249.31 OQS01130.1 - 1.4e-09 38.0 0.9 2.4e-09 37.2 0.0 1.8 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OQS01130.1 - 0.00045 20.4 0.2 0.0011 19.1 0.2 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 OQS01131.1 - 9.6e-08 32.1 0.0 1.5e-07 31.5 0.0 1.3 1 0 0 1 1 1 1 Myb-like DNA-binding domain CBM_1 PF00734.18 OQS01132.1 - 5.5e-24 83.8 75.5 1.5e-10 40.9 5.1 6.7 6 0 0 6 6 6 6 Fungal cellulose binding domain IF-2B PF01008.17 OQS01132.1 - 0.27 10.4 0.4 3.7 6.7 0.0 2.7 2 1 1 3 3 3 0 Initiation factor 2 subunit family FSAP_sig_propep PF03032.15 OQS01132.1 - 0.88 9.7 3.5 9.7 6.3 0.0 3.4 4 0 0 4 4 4 0 Frog skin active peptide family signal and propeptide CLIP_SPH_Scar PF18399.1 OQS01132.1 - 1.2 9.3 33.4 1.9 8.7 0.7 5.4 5 0 0 5 5 5 0 Clip-domain serine protease homolog Scarface TRP PF06011.12 OQS01133.1 - 1.9e-11 43.4 26.9 5.2e-11 41.9 26.7 1.7 1 1 1 2 2 2 1 Transient receptor potential (TRP) ion channel CybS PF05328.12 OQS01133.1 - 0.03 14.0 0.0 0.11 12.2 0.0 2.0 1 0 0 1 1 1 0 CybS, succinate dehydrogenase cytochrome B small subunit PDR_CDR PF06422.12 OQS01133.1 - 0.22 11.4 0.2 0.62 10.0 0.0 1.9 1 1 0 1 1 1 0 CDR ABC transporter DUF945 PF06097.11 OQS01133.1 - 0.29 10.2 1.7 0.43 9.6 1.7 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF945) p450 PF00067.22 OQS01134.1 - 1.2e-61 208.9 0.0 1.5e-61 208.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Thr_synth_N PF14821.6 OQS01135.1 - 0.14 12.3 0.0 0.35 11.1 0.0 1.6 2 0 0 2 2 2 0 Threonine synthase N terminus AAA_6 PF12774.7 OQS01226.1 - 0.025 13.5 0.2 0.03 13.3 0.2 1.1 1 0 0 1 1 1 0 Hydrolytic ATP binding site of dynein motor region Pkinase PF00069.25 OQS01227.1 - 1.6e-72 244.0 0.0 2.8e-72 243.2 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQS01227.1 - 2.6e-50 171.1 0.0 1.8e-49 168.4 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase G-gamma PF00631.22 OQS01227.1 - 1.6e-10 40.8 0.0 5.5e-10 39.1 0.0 1.9 1 0 0 1 1 1 1 GGL domain MIT PF04212.18 OQS01227.1 - 8.7e-05 22.5 1.5 0.1 12.7 0.1 2.8 2 1 0 2 2 2 2 MIT (microtubule interacting and transport) domain DUF3543 PF12063.8 OQS01227.1 - 0.00038 19.9 1.4 0.0053 16.2 1.4 2.4 1 1 0 1 1 1 1 Domain of unknown function (DUF3543) APH PF01636.23 OQS01227.1 - 0.002 18.1 0.0 0.0055 16.7 0.0 1.8 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 OQS01227.1 - 0.0037 16.1 0.0 0.0085 14.9 0.0 1.5 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 OQS01227.1 - 0.0041 16.5 1.2 0.024 14.0 0.0 2.2 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Tektin PF03148.14 OQS01227.1 - 0.024 13.4 2.9 0.037 12.8 2.9 1.2 1 0 0 1 1 1 0 Tektin family XhlA PF10779.9 OQS01227.1 - 0.23 11.7 0.8 0.52 10.6 0.8 1.5 1 0 0 1 1 1 0 Haemolysin XhlA DUF4200 PF13863.6 OQS01227.1 - 1.4 9.3 8.2 0.34 11.3 4.9 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) OmpH PF03938.14 OQS01228.1 - 0.63 10.4 32.8 0.79 10.1 7.9 2.9 1 1 2 3 3 3 0 Outer membrane protein (OmpH-like) DUF3544 PF12064.8 OQS01228.1 - 1.2 9.4 11.8 2.3 8.4 7.3 2.4 1 1 1 2 2 2 0 Protein kinase C-binding protein 1 DUF3584 PF12128.8 OQS01228.1 - 2.1 5.8 33.6 7.3 4.0 33.8 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3584) DUF1664 PF07889.12 OQS01228.1 - 5.1 7.1 21.7 0.065 13.3 1.8 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) PRKG1_interact PF15898.5 OQS01228.1 - 6.1 7.8 36.2 0.059 14.3 6.0 3.2 2 1 1 3 3 3 0 cGMP-dependent protein kinase interacting domain SURF6 PF04935.12 OQS01229.1 - 2.9e-25 89.3 51.9 2.9e-25 89.3 51.9 2.4 1 1 1 2 2 2 1 Surfeit locus protein 6 RRP14 PF15459.6 OQS01229.1 - 4.1e-08 33.7 1.1 4.1e-08 33.7 1.1 7.3 4 2 0 4 4 4 1 60S ribosome biogenesis protein Rrp14 DUF4111 PF13427.6 OQS01230.1 - 1.7e-33 114.9 0.0 2.7e-33 114.2 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4111) Polbeta PF18765.1 OQS01230.1 - 2.9e-07 30.5 0.0 1.2e-05 25.3 0.0 2.3 2 0 0 2 2 2 1 Polymerase beta, Nucleotidyltransferase NTP_transf_2 PF01909.23 OQS01230.1 - 8.2e-07 29.2 0.0 2.3e-05 24.6 0.0 2.3 2 0 0 2 2 2 1 Nucleotidyltransferase domain Ricin_B_lectin PF00652.22 OQS01238.1 - 3.7e-12 46.6 7.6 3.3e-10 40.3 4.8 2.1 2 0 0 2 2 2 2 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.6 OQS01238.1 - 0.00096 19.8 11.3 0.08 13.7 4.2 3.2 1 1 2 3 3 3 3 Ricin-type beta-trefoil lectin domain-like Aa_trans PF01490.18 OQS01550.1 - 5.4e-27 94.5 13.3 6.4e-27 94.3 13.3 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Aa_trans PF01490.18 OQS01619.1 - 3.7e-15 55.5 3.7 4.9e-15 55.2 3.7 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Fimbrial_K88 PF02432.15 OQS01619.1 - 0.054 13.5 0.0 0.076 13.0 0.0 1.3 1 0 0 1 1 1 0 Fimbrial, major and minor subunit VitK2_biosynth PF02621.14 OQS01683.1 - 0.055 13.0 0.2 0.076 12.5 0.2 1.2 1 0 0 1 1 1 0 Menaquinone biosynthesis Holin_SPP1 PF04688.13 OQS01683.1 - 0.4 10.9 4.0 0.87 9.8 0.5 2.8 3 0 0 3 3 3 0 SPP1 phage holin MFS_1_like PF12832.7 OQS01732.1 - 3.4 6.4 8.7 7.4 5.3 8.7 1.7 1 1 0 1 1 1 0 MFS_1 like family HC2 PF07382.11 OQS01775.1 - 0.00054 20.1 17.0 0.00054 20.1 17.0 1.5 2 0 0 2 2 2 1 Histone H1-like nucleoprotein HC2 HTH_13 PF11972.8 OQS01775.1 - 0.0022 18.0 19.9 27 4.9 4.8 5.1 1 1 1 2 2 2 1 HTH DNA binding domain ASFV_J13L PF05568.11 OQS01775.1 - 0.78 9.5 8.2 0.44 10.3 1.2 2.4 1 1 1 2 2 2 0 African swine fever virus J13L protein Pirin_C PF05726.13 OQS01776.1 - 6.2e-18 65.1 0.0 5.4e-14 52.4 0.0 2.1 1 1 1 2 2 2 2 Pirin C-terminal cupin domain N36 PF11438.8 OQS01776.1 - 0.15 11.9 0.2 6.3 6.7 0.0 2.4 2 0 0 2 2 2 0 36-mer N-terminal peptide of the N protein (N36) Aa_trans PF01490.18 OQS01777.1 - 4.7e-13 48.6 0.9 5.4e-13 48.4 0.9 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Fimbrial_K88 PF02432.15 OQS01777.1 - 0.051 13.5 0.0 0.071 13.1 0.0 1.3 1 0 0 1 1 1 0 Fimbrial, major and minor subunit YrhC PF14143.6 OQS01777.1 - 0.57 10.3 2.9 25 5.1 0.1 3.3 3 1 0 3 3 3 0 YrhC-like protein Disintegrin PF00200.23 OQS01779.1 - 1e-07 32.6 14.3 1e-07 32.6 14.3 2.2 1 1 1 2 2 2 1 Disintegrin Ank_2 PF12796.7 OQS01780.1 - 2.6e-10 40.7 0.2 2.9e-10 40.6 0.2 1.1 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 OQS01780.1 - 2.9e-08 33.8 1.7 9.9e-06 25.8 0.1 2.1 1 1 1 2 2 2 2 Ankyrin repeat Ank_4 PF13637.6 OQS01780.1 - 7e-08 32.9 0.1 8.8e-08 32.6 0.1 1.2 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQS01780.1 - 6.7e-05 23.0 0.1 0.005 17.2 0.0 2.3 2 0 0 2 2 2 1 Ankyrin repeat Ank_5 PF13857.6 OQS01780.1 - 0.0035 17.6 0.1 0.0059 16.9 0.1 1.4 1 0 0 1 1 1 1 Ankyrin repeats (many copies) HC2 PF07382.11 OQS01781.1 - 0.0008 19.5 17.4 0.0008 19.5 17.4 1.5 2 0 0 2 2 2 1 Histone H1-like nucleoprotein HC2 HTH_13 PF11972.8 OQS01781.1 - 0.0023 17.9 20.0 0.54 10.4 0.4 5.0 1 1 3 4 4 4 3 HTH DNA binding domain ASFV_J13L PF05568.11 OQS01781.1 - 0.81 9.4 8.2 17 5.1 8.2 2.4 1 1 0 1 1 1 0 African swine fever virus J13L protein DUF2828 PF11443.8 OQS01783.1 - 2.3e-25 88.8 0.0 2.3e-25 88.8 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF2828) Peptidase_C1 PF00112.23 OQS01784.1 - 2.6e-23 83.2 1.4 3.8e-23 82.7 1.4 1.2 1 0 0 1 1 1 1 Papain family cysteine protease IGFBP PF00219.18 OQS01784.1 - 0.014 16.0 2.1 0.032 14.9 2.1 1.6 1 0 0 1 1 1 0 Insulin-like growth factor binding protein Peptidase_C1_2 PF03051.15 OQS01784.1 - 0.086 11.6 0.1 0.11 11.2 0.1 1.1 1 0 0 1 1 1 0 Peptidase C1-like family SSTK-IP PF15836.5 OQS01784.1 - 1.5 9.0 5.1 12 6.1 5.1 2.2 1 1 0 1 1 1 0 SSTK-interacting protein, TSSK6-activating co-chaperone protein Aa_trans PF01490.18 OQS01785.1 - 1.7e-12 46.8 3.9 1.9e-12 46.6 3.9 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Fimbrial_K88 PF02432.15 OQS01785.1 - 0.032 14.2 0.0 0.042 13.8 0.0 1.3 1 0 0 1 1 1 0 Fimbrial, major and minor subunit Ank_2 PF12796.7 OQS01786.1 - 3.3e-14 53.2 0.0 4.9e-14 52.7 0.0 1.3 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 OQS01786.1 - 2.1e-11 43.7 0.5 6.6e-05 23.2 0.0 2.3 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.6 OQS01786.1 - 2.3e-10 40.8 0.4 5.2e-06 26.9 0.1 2.2 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQS01786.1 - 5.2e-10 38.7 0.2 5.1e-05 23.4 0.0 2.6 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 OQS01786.1 - 2.7e-06 27.6 0.2 0.0013 18.9 0.1 2.1 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Imm_superinfect PF14373.6 OQS01786.1 - 0.01 15.8 0.0 0.35 10.8 0.0 2.2 2 0 0 2 2 2 0 Superinfection immunity protein Rhomboid_N PF12122.8 OQS01787.1 - 0.0097 16.0 0.3 9.7 6.4 0.0 3.0 2 0 0 2 2 2 2 Cytoplasmic N-terminal domain of rhomboid serine protease DUF959 PF06121.14 OQS01787.1 - 0.82 9.9 11.4 2 8.6 0.3 3.0 3 0 0 3 3 3 0 Domain of Unknown Function (DUF959) GCP5-Mod21 PF14609.6 OQS01787.1 - 3.2 6.0 11.1 4.7 5.4 1.6 2.4 2 0 0 2 2 2 0 gamma-Tubulin ring complex non-core subunit mod21 Aa_trans PF01490.18 OQS01788.1 - 5.2e-08 32.0 0.0 5.4e-08 31.9 0.0 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DUF3959 PF13105.6 OQS01788.1 - 0.26 10.8 1.2 0.3 10.6 1.0 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3959) DUF5453 PF17534.2 OQS01790.1 - 0.013 15.5 0.5 0.015 15.2 0.5 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5453) ABC2_membrane PF01061.24 OQS01791.1 - 8.2e-17 61.3 17.3 9.5e-17 61.1 17.3 1.0 1 0 0 1 1 1 1 ABC-2 type transporter ABC2_membrane_3 PF12698.7 OQS01791.1 - 0.016 14.4 11.2 0.015 14.4 11.2 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein ABC2_membrane_2 PF12679.7 OQS01791.1 - 0.63 9.3 5.8 0.65 9.2 5.8 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein PDR_assoc PF08370.11 OQS01791.1 - 0.75 9.6 0.0 0.75 9.6 0.0 3.0 4 0 0 4 4 4 0 Plant PDR ABC transporter associated DUF3899 PF13038.6 OQS01792.1 - 0.2 12.2 0.3 0.37 11.3 0.2 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF3899) Chromo PF00385.24 OQS01793.1 - 7.1e-09 35.4 1.6 1.7e-08 34.3 1.6 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain HTH_Tnp_1 PF01527.20 OQS01793.1 - 0.015 15.6 0.1 0.025 14.9 0.1 1.4 1 0 0 1 1 1 0 Transposase Rhomboid_N PF12122.8 OQS01794.1 - 0.009 16.2 0.3 9.1 6.5 0.0 3.0 2 0 0 2 2 2 2 Cytoplasmic N-terminal domain of rhomboid serine protease DUF3223 PF11523.8 OQS01795.1 - 0.053 14.4 0.1 1.4 9.8 0.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3223) Sec62 PF03839.16 OQS01796.1 - 6.3e-51 172.9 5.2 1.4e-31 109.7 0.4 2.3 2 0 0 2 2 2 2 Translocation protein Sec62 ubiquitin PF00240.23 OQS01796.1 - 7.5e-16 57.6 2.7 9.9e-16 57.3 0.1 2.4 3 0 0 3 3 3 1 Ubiquitin family DEP PF00610.21 OQS01796.1 - 0.00042 20.3 0.0 0.042 13.9 0.0 2.7 2 0 0 2 2 2 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Rad60-SLD PF11976.8 OQS01796.1 - 0.00061 19.6 0.0 0.0055 16.5 0.0 2.3 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like STI1 PF17830.1 OQS01796.1 - 0.0012 18.7 7.2 0.0012 18.7 7.2 4.9 2 2 2 4 4 4 3 STI1 domain UBA PF00627.31 OQS01796.1 - 0.0053 16.6 0.1 0.028 14.3 0.1 2.3 1 0 0 1 1 1 1 UBA/TS-N domain E1_UFD PF09358.10 OQS01796.1 - 0.14 12.9 0.1 0.39 11.5 0.1 1.7 1 0 0 1 1 1 0 Ubiquitin fold domain DUF2407 PF10302.9 OQS01796.1 - 0.15 12.6 0.0 0.58 10.7 0.0 2.0 2 0 0 2 2 2 0 DUF2407 ubiquitin-like domain Dynactin_p22 PF07426.11 OQS01796.1 - 0.62 9.9 3.2 0.82 9.5 0.4 2.4 2 1 0 2 2 2 0 Dynactin subunit p22 ScsC_N PF18312.1 OQS01796.1 - 2.7 7.9 6.5 6.3 6.7 0.0 4.5 5 0 0 5 5 5 0 Copper resistance protein ScsC N-terminal domain MgtE PF01769.16 OQS01796.1 - 8.7 6.7 11.2 19 5.7 4.1 2.5 2 0 0 2 2 2 0 Divalent cation transporter Mannosyl_trans3 PF11051.8 OQS01797.1 - 3.8e-27 95.3 0.1 4.7e-25 88.5 0.1 2.2 1 1 0 1 1 1 1 Mannosyltransferase putative PepSY_TM PF03929.16 OQS01797.1 - 0.047 13.3 0.9 0.067 12.9 0.1 1.6 2 0 0 2 2 2 0 PepSY-associated TM region Ank_4 PF13637.6 OQS01798.1 - 4.8e-18 65.3 4.7 2.6e-05 24.7 0.0 3.3 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 OQS01798.1 - 2.6e-17 62.6 0.9 0.00016 21.9 0.1 4.1 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 OQS01798.1 - 5.2e-14 52.6 1.6 8.8e-07 29.4 0.1 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OQS01798.1 - 3.7e-07 29.9 0.3 0.71 10.6 0.0 4.6 5 0 0 5 5 5 2 Ankyrin repeat DUF5049 PF16468.5 OQS01798.1 - 0.00019 21.3 0.7 1.2 9.1 0.0 4.3 3 2 2 5 5 5 1 Domain of unknown function (DUF5049) BTHB PF18410.1 OQS01798.1 - 0.036 13.9 0.0 6.1 6.7 0.0 3.4 4 0 0 4 4 4 0 Basic tilted helix bundle domain ENTH PF01417.20 OQS01798.1 - 0.037 14.1 0.3 9.7 6.3 0.0 2.7 1 1 1 2 2 2 0 ENTH domain NCE101 PF11654.8 OQS01798.1 - 2.6 7.8 5.0 1.6e+02 2.1 0.0 4.3 5 0 0 5 5 5 0 Non-classical export protein 1 Ank_2 PF12796.7 OQS01799.1 - 6.4e-23 81.1 3.0 0.0002 21.9 0.2 4.2 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OQS01799.1 - 4.8e-20 71.4 0.6 0.0027 18.0 0.0 6.1 2 1 4 6 6 6 5 Ankyrin repeats (many copies) Ank_4 PF13637.6 OQS01799.1 - 1.1e-16 60.9 0.8 0.00023 21.6 0.0 5.3 3 2 2 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQS01799.1 - 9.3e-12 44.1 0.1 0.6 10.8 0.0 7.6 7 1 1 8 8 8 2 Ankyrin repeat DUF5049 PF16468.5 OQS01799.1 - 1.3e-08 34.6 2.3 12 5.9 0.0 7.3 2 2 6 8 8 8 2 Domain of unknown function (DUF5049) DUF3447 PF11929.8 OQS01799.1 - 0.00013 21.9 0.9 10 6.2 0.1 3.9 1 1 2 4 4 4 2 Domain of unknown function (DUF3447) Ank PF00023.30 OQS01799.1 - 0.024 15.1 0.2 2.2e+02 2.5 0.0 5.3 4 2 0 4 4 4 0 Ankyrin repeat Tom37 PF10568.9 OQS01799.1 - 0.024 14.9 4.9 25 5.2 0.6 4.7 2 1 1 3 3 3 0 Outer mitochondrial membrane transport complex protein Ank_4 PF13637.6 OQS01801.1 - 2e-08 34.6 0.2 1.3e-05 25.7 0.0 2.3 2 1 0 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 OQS01801.1 - 7.7e-06 26.4 0.2 4e-05 24.1 0.0 1.9 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OQS01801.1 - 0.00032 20.9 0.6 0.17 12.2 0.1 3.1 1 1 3 4 4 4 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQS01801.1 - 0.0016 18.7 0.1 6.3 7.7 0.0 3.2 3 1 1 4 4 4 2 Ankyrin repeat Ank_4 PF13637.6 OQS01802.1 - 3.2e-26 91.3 1.0 2.6e-05 24.7 0.0 5.9 7 0 0 7 7 7 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 OQS01802.1 - 2.8e-23 81.7 3.3 0.0016 18.7 0.0 8.8 5 1 4 9 9 9 6 Ankyrin repeats (many copies) Ank_2 PF12796.7 OQS01802.1 - 3.7e-21 75.5 11.4 2.4e-05 24.8 0.3 5.6 3 2 2 5 5 5 4 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OQS01802.1 - 1.6e-14 52.5 0.0 1.3 9.8 0.0 9.9 11 0 0 11 11 11 3 Ankyrin repeat BTHB PF18410.1 OQS01802.1 - 0.0069 16.2 0.1 9.8 6.1 0.0 4.3 4 1 0 4 4 4 1 Basic tilted helix bundle domain Ank PF00023.30 OQS01802.1 - 0.073 13.6 1.5 3.1e+02 2.1 0.0 6.1 7 1 0 7 7 7 0 Ankyrin repeat HA PF03457.14 OQS01802.1 - 0.31 11.4 1.0 34 4.9 0.0 4.7 5 1 0 5 5 5 0 Helicase associated domain Baculo_LEF5_C PF11792.8 OQS01802.1 - 2.3 8.0 6.3 19 5.0 0.0 3.9 4 0 0 4 4 4 0 Baculoviridae late expression factor 5 C-terminal domain Ank_4 PF13637.6 OQS01803.1 - 1.7e-50 168.7 20.2 2.3e-07 31.2 0.1 10.7 7 4 6 13 13 13 12 Ankyrin repeats (many copies) Ank_2 PF12796.7 OQS01803.1 - 2.6e-42 143.3 33.0 1.1e-08 35.6 1.5 7.9 1 1 6 8 8 8 8 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OQS01803.1 - 4e-39 132.2 28.3 0.0012 19.1 0.0 15.0 4 3 10 15 15 15 11 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQS01803.1 - 9.5e-22 74.8 18.6 2.5 9.0 0.0 15.3 15 1 1 16 16 16 6 Ankyrin repeat DUF5049 PF16468.5 OQS01803.1 - 1.1e-09 38.0 10.6 3.6 7.6 0.1 10.7 7 4 5 12 12 12 2 Domain of unknown function (DUF5049) Ank PF00023.30 OQS01803.1 - 2.3e-05 24.6 15.7 38 5.0 0.0 11.9 6 4 4 10 10 10 0 Ankyrin repeat DUF1979 PF09322.10 OQS01803.1 - 0.084 12.8 0.0 93 3.0 0.0 3.9 4 0 0 4 4 4 0 Domain of unknown function (DUF1979) DUF1843 PF08898.10 OQS01803.1 - 5.3 7.6 11.1 17 6.0 0.1 6.1 7 2 1 8 8 8 0 Domain of unknown function (DUF1843) adh_short PF00106.25 OQS01804.1 - 8.7e-29 100.4 0.0 4.5e-24 85.0 0.0 2.2 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 OQS01804.1 - 3e-18 66.3 0.0 8.3e-17 61.5 0.0 2.1 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OQS01804.1 - 2.8e-08 33.9 0.0 5.2e-08 33.0 0.0 1.5 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 OQS01804.1 - 0.032 13.7 0.0 0.093 12.2 0.0 1.7 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family YjeF_N PF03853.15 OQS01804.1 - 0.051 13.5 0.0 0.084 12.8 0.0 1.3 1 0 0 1 1 1 0 YjeF-related protein N-terminus Ank_4 PF13637.6 OQS01805.1 - 3.1e-12 46.8 1.6 1.5e-07 31.9 0.2 3.2 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 OQS01805.1 - 3.7e-10 40.2 3.5 3.2e-08 34.1 0.9 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OQS01805.1 - 7.6e-09 35.7 3.2 0.0012 19.1 0.1 4.1 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQS01805.1 - 2.4e-07 30.5 1.7 0.09 13.4 0.0 4.7 4 1 1 5 5 5 2 Ankyrin repeat Ank PF00023.30 OQS01805.1 - 0.053 14.0 0.6 4.6 7.9 0.6 3.4 1 1 1 2 2 2 0 Ankyrin repeat Ank_4 PF13637.6 OQS01806.1 - 1.1e-32 111.9 11.6 1.3e-07 32.0 0.1 6.5 5 2 1 6 6 6 5 Ankyrin repeats (many copies) Ank_2 PF12796.7 OQS01806.1 - 1.5e-29 102.4 17.9 1e-11 45.3 1.1 5.0 1 1 5 6 6 6 5 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OQS01806.1 - 1.1e-28 98.9 14.5 7.4e-06 26.1 0.2 9.4 2 1 8 10 10 10 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQS01806.1 - 2.5e-18 64.3 7.5 0.028 14.9 0.0 9.8 9 1 1 10 10 10 3 Ankyrin repeat Ank PF00023.30 OQS01806.1 - 1.6e-06 28.3 10.0 0.62 10.6 0.0 7.5 5 2 1 6 6 6 1 Ankyrin repeat HA PF03457.14 OQS01806.1 - 0.0022 18.3 4.8 24 5.4 0.0 5.8 5 2 2 7 7 7 0 Helicase associated domain AhpC-TSA PF00578.21 OQS01806.1 - 0.15 12.0 0.0 2.6 8.0 0.0 2.6 2 1 1 3 3 3 0 AhpC/TSA family ENTH PF01417.20 OQS01806.1 - 0.21 11.6 1.5 9.2 6.3 0.1 3.4 2 1 1 3 3 3 0 ENTH domain DNTTIP1_dimer PF18192.1 OQS01806.1 - 0.33 11.3 2.0 38 4.7 0.1 4.2 4 1 2 6 6 6 0 DNTTIP1 dimerisation domain Mannosyl_trans3 PF11051.8 OQS01807.1 - 1.4e-05 24.6 0.5 0.02 14.3 0.0 3.1 1 1 2 3 3 3 3 Mannosyltransferase putative Acyltransferase PF01553.21 OQS01809.1 - 3.7e-19 68.7 0.0 7.6e-19 67.7 0.0 1.5 1 1 0 1 1 1 1 Acyltransferase DUF4405 PF14358.6 OQS01809.1 - 0.77 10.3 11.5 0.053 14.1 5.6 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4405) NuA4 PF09340.10 OQS01810.1 - 3.2e-13 49.4 0.0 6.9e-13 48.3 0.0 1.6 1 0 0 1 1 1 1 Histone acetyltransferase subunit NuA4 DDE_1 PF03184.19 OQS01811.1 - 5.4e-30 104.3 0.0 7.6e-30 103.8 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.6 OQS01811.1 - 0.047 13.4 0.0 0.093 12.5 0.0 1.5 1 0 0 1 1 1 0 DDE superfamily endonuclease Arf PF00025.21 OQS01814.1 - 2.4e-57 193.2 0.1 2.7e-57 193.0 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 OQS01814.1 - 7e-11 42.4 0.2 9.5e-11 42.0 0.2 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase G-alpha PF00503.20 OQS01814.1 - 5.1e-10 39.0 0.1 7.2e-10 38.5 0.1 1.2 1 0 0 1 1 1 1 G-protein alpha subunit Ras PF00071.22 OQS01814.1 - 1.2e-09 38.0 0.1 1.5e-09 37.6 0.1 1.1 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 OQS01814.1 - 2.5e-06 27.0 0.1 3e-06 26.8 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 OQS01814.1 - 5.8e-06 25.9 0.0 7.2e-06 25.6 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 OQS01814.1 - 0.012 15.7 0.2 0.016 15.3 0.2 1.2 1 0 0 1 1 1 0 50S ribosome-binding GTPase LT-IIB PF06453.11 OQS01814.1 - 0.15 12.0 0.0 0.19 11.6 0.0 1.2 1 0 0 1 1 1 0 Type II heat-labile enterotoxin , B subunit (LT-IIB) IQ PF00612.27 OQS01815.1 - 1.8e-07 30.4 13.7 0.00013 21.4 2.7 3.0 2 0 0 2 2 2 2 IQ calmodulin-binding motif RmuC PF02646.16 OQS01815.1 - 0.023 13.8 4.2 0.19 10.9 0.0 2.5 2 0 0 2 2 2 0 RmuC family HA PF03457.14 OQS01816.1 - 3.7e-27 94.5 0.9 2.2e-12 47.1 0.1 3.7 3 0 0 3 3 3 3 Helicase associated domain Peptidase_M20 PF01546.28 OQS01816.1 - 9.6e-21 74.4 1.1 1.5e-20 73.8 1.1 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 OQS01816.1 - 3e-09 36.8 0.5 1.6e-08 34.4 0.2 2.1 2 0 0 2 2 2 1 Peptidase dimerisation domain Pepsin-I3 PF06394.13 OQS01816.1 - 0.15 12.3 0.1 0.32 11.2 0.1 1.6 1 0 0 1 1 1 0 Pepsin inhibitor-3-like repeated domain Exo_endo_phos PF03372.23 OQS01818.1 - 0.014 14.9 1.6 0.026 14.0 1.6 1.5 1 0 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family Kelch_5 PF13854.6 OQS01819.1 - 4.6e-16 58.4 0.1 0.012 15.5 0.0 5.5 5 0 0 5 5 5 4 Kelch motif Kelch_3 PF13415.6 OQS01819.1 - 1.9e-14 53.5 0.0 0.00078 19.7 0.0 5.1 5 0 0 5 5 5 3 Galactose oxidase, central domain Kelch_4 PF13418.6 OQS01819.1 - 4.1e-11 42.7 3.7 9.5e-06 25.5 0.0 5.5 6 0 0 6 6 6 2 Galactose oxidase, central domain Kelch_1 PF01344.25 OQS01819.1 - 0.00021 20.8 0.1 0.0034 16.9 0.0 3.0 4 0 0 4 4 4 1 Kelch motif RNA_pol_L_2 PF13656.6 OQS01821.1 - 5.5e-25 86.9 0.0 6.7e-25 86.7 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.24 OQS01821.1 - 1.5e-07 30.7 0.0 2.1e-07 30.3 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain VirK PF06903.12 OQS01821.1 - 0.13 12.4 0.0 0.21 11.7 0.0 1.4 1 1 0 1 1 1 0 VirK protein Epimerase PF01370.21 OQS01822.1 - 1.1e-57 195.3 0.1 2.1e-57 194.4 0.1 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 OQS01822.1 - 1.3e-49 169.4 0.0 1.3e-49 169.4 0.0 3.0 2 2 0 2 2 2 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 OQS01822.1 - 8.9e-27 93.8 0.0 2e-26 92.6 0.0 1.6 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 OQS01822.1 - 6.7e-17 61.5 0.3 7e-14 51.6 0.0 2.9 1 1 0 2 2 2 2 Male sterility protein RmlD_sub_bind PF04321.17 OQS01822.1 - 6.2e-16 58.3 1.2 1.1e-15 57.5 0.0 1.9 2 0 0 2 2 2 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 OQS01822.1 - 1.1e-14 54.3 0.1 7.4e-14 51.6 0.1 2.4 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.6 OQS01822.1 - 6.8e-09 35.9 0.0 1.8e-08 34.5 0.0 1.7 1 0 0 1 1 1 1 NAD(P)H-binding adh_short PF00106.25 OQS01822.1 - 0.003 17.1 2.1 0.0064 16.0 0.1 2.7 2 1 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 OQS01822.1 - 0.0048 16.8 0.7 0.071 13.0 0.7 3.0 1 1 0 1 1 1 1 KR domain ABC_tran PF00005.27 OQS01823.1 - 2e-30 106.1 0.0 4.2e-30 105.0 0.0 1.5 2 0 0 2 2 2 1 ABC transporter SMC_N PF02463.19 OQS01823.1 - 2.3e-07 30.5 0.8 3.4e-05 23.4 0.8 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain DUF87 PF01935.17 OQS01823.1 - 0.0028 17.8 0.1 0.0059 16.7 0.1 1.5 1 0 0 1 1 1 1 Helicase HerA, central domain AAA_21 PF13304.6 OQS01823.1 - 0.0055 16.5 0.1 1.3 8.7 0.0 2.2 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system MMR_HSR1 PF01926.23 OQS01823.1 - 0.0088 16.1 0.0 0.021 14.9 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.6 OQS01823.1 - 0.014 15.7 0.1 0.052 13.8 0.1 1.8 1 1 0 1 1 1 0 AAA domain DEAD PF00270.29 OQS01823.1 - 0.017 14.9 0.3 0.87 9.3 0.0 2.2 2 0 0 2 2 2 0 DEAD/DEAH box helicase AAA_29 PF13555.6 OQS01823.1 - 0.03 14.1 0.0 0.071 12.9 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.6 OQS01823.1 - 0.063 13.8 0.0 0.099 13.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.13 OQS01823.1 - 0.071 12.3 0.0 0.1 11.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) TrwB_AAD_bind PF10412.9 OQS01823.1 - 0.074 11.9 0.0 0.13 11.2 0.0 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain AAA_30 PF13604.6 OQS01823.1 - 0.15 11.8 0.1 0.97 9.1 0.0 1.9 2 0 0 2 2 2 0 AAA domain ABC_membrane PF00664.23 OQS01824.1 - 1.5e-50 172.4 42.6 3.4e-33 115.5 20.8 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 OQS01824.1 - 1.2e-26 93.8 1.8 1.9e-19 70.5 0.0 2.6 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 OQS01824.1 - 2.8e-06 26.9 5.3 0.011 15.1 0.3 3.3 2 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 OQS01824.1 - 1.5e-05 24.6 3.6 0.0069 16.1 0.4 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_21 PF13304.6 OQS01824.1 - 1.7e-05 24.8 0.3 0.00039 20.3 0.0 2.6 3 0 0 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 OQS01824.1 - 2.7e-05 24.8 0.1 0.059 13.9 0.0 2.5 2 0 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 OQS01824.1 - 7.5e-05 22.7 1.2 0.0036 17.2 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase MMR_HSR1 PF01926.23 OQS01824.1 - 0.00017 21.6 2.1 0.08 13.0 0.0 3.0 3 0 0 3 3 3 2 50S ribosome-binding GTPase Dynamin_N PF00350.23 OQS01824.1 - 0.0065 16.5 1.0 0.094 12.8 0.0 2.4 2 0 0 2 2 2 1 Dynamin family AAA_22 PF13401.6 OQS01824.1 - 0.0071 16.6 0.5 0.56 10.5 0.0 2.6 2 0 0 2 2 2 1 AAA domain FtsK_SpoIIIE PF01580.18 OQS01824.1 - 0.016 14.5 0.6 1.3 8.3 0.1 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family T2SSE PF00437.20 OQS01824.1 - 0.017 14.2 0.3 0.065 12.3 0.1 1.9 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_15 PF13175.6 OQS01824.1 - 0.019 14.7 2.0 0.07 12.8 0.1 2.1 2 0 0 2 2 2 0 AAA ATPase domain DUF87 PF01935.17 OQS01824.1 - 0.02 15.0 1.6 1.6 8.8 0.1 2.4 2 0 0 2 2 2 0 Helicase HerA, central domain AAA_16 PF13191.6 OQS01824.1 - 0.023 15.1 1.0 0.073 13.5 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain DUF815 PF05673.13 OQS01824.1 - 0.066 12.4 0.8 0.52 9.4 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_30 PF13604.6 OQS01824.1 - 0.088 12.5 0.3 0.26 11.0 0.0 1.9 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.22 OQS01824.1 - 0.11 11.6 0.3 1.7 7.8 0.0 2.2 2 0 0 2 2 2 0 NB-ARC domain AAA_7 PF12775.7 OQS01824.1 - 0.14 11.7 0.8 1.5 8.3 0.1 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region PI-PLC-X PF00388.19 OQS01824.1 - 0.16 11.5 0.0 0.33 10.5 0.0 1.4 1 0 0 1 1 1 0 Phosphatidylinositol-specific phospholipase C, X domain cobW PF02492.19 OQS01824.1 - 0.2 11.2 2.4 0.25 10.9 0.1 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Zeta_toxin PF06414.12 OQS01824.1 - 1 8.6 3.2 0.58 9.4 0.0 2.1 3 0 0 3 3 3 0 Zeta toxin Metallophos PF00149.28 OQS01825.1 - 1.8e-29 103.7 11.1 5.9e-15 56.3 1.9 2.5 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase Pur_ac_phosph_N PF16656.5 OQS01825.1 - 1e-15 58.1 9.5 1.9e-08 34.7 2.0 2.7 2 0 0 2 2 2 2 Purple acid Phosphatase, N-terminal domain Metallophos_C PF14008.6 OQS01825.1 - 3.3e-12 47.1 3.0 3e-05 24.8 0.2 2.8 2 0 0 2 2 2 2 Iron/zinc purple acid phosphatase-like protein C Metallophos_2 PF12850.7 OQS01825.1 - 2e-11 44.4 1.3 0.0064 16.7 0.0 4.2 4 0 0 4 4 4 3 Calcineurin-like phosphoesterase superfamily domain fn3 PF00041.21 OQS01825.1 - 0.00083 19.7 2.9 0.67 10.3 0.3 2.8 3 0 0 3 3 3 2 Fibronectin type III domain UDPGP PF01704.18 OQS01825.1 - 0.036 12.7 0.0 5.3 5.6 0.0 2.2 2 0 0 2 2 2 0 UTP--glucose-1-phosphate uridylyltransferase Collagen_bind PF05737.12 OQS01825.1 - 0.042 14.0 0.6 12 6.1 0.1 2.5 2 0 0 2 2 2 0 Collagen binding domain FeThRed_B PF02943.15 OQS01825.1 - 0.18 11.8 1.5 14 5.7 0.1 2.4 2 0 0 2 2 2 0 Ferredoxin thioredoxin reductase catalytic beta chain Metallophos_3 PF14582.6 OQS01825.1 - 0.2 10.9 0.0 12 5.1 0.0 2.3 2 0 0 2 2 2 0 Metallophosphoesterase, calcineurin superfamily E7R PF17467.2 OQS01825.1 - 0.3 11.3 5.0 6.2 7.0 0.0 3.8 4 0 0 4 4 4 0 Viral Protein E7 Ricin_B_lectin PF00652.22 OQS01826.1 - 8.9e-20 71.2 9.6 2.3e-13 50.5 4.5 3.2 2 1 1 3 3 3 3 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.6 OQS01826.1 - 4.2e-08 33.8 9.9 0.00068 20.3 1.2 3.7 2 1 1 3 3 3 3 Ricin-type beta-trefoil lectin domain-like CDtoxinA PF03498.14 OQS01826.1 - 0.022 14.4 9.8 0.14 11.7 3.0 3.3 3 1 0 3 3 3 0 Cytolethal distending toxin A/C domain YHS PF04945.13 OQS01826.1 - 0.11 12.6 0.2 1.9 8.6 0.0 2.6 2 0 0 2 2 2 0 YHS domain Ricin_B_lectin PF00652.22 OQS01827.1 - 0.0014 18.9 0.4 0.0029 17.9 0.4 1.5 1 1 0 1 1 1 1 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.6 OQS01827.1 - 0.027 15.2 0.4 0.053 14.2 0.4 1.5 1 0 0 1 1 1 0 Ricin-type beta-trefoil lectin domain-like Ricin_B_lectin PF00652.22 OQS01828.1 - 1.3e-15 57.7 10.0 8.4e-10 39.0 2.3 3.4 1 1 2 3 3 3 3 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.6 OQS01828.1 - 6.1e-09 36.5 4.3 0.00017 22.2 0.1 4.1 2 2 2 4 4 4 3 Ricin-type beta-trefoil lectin domain-like Lectin_C PF00059.21 OQS01828.1 - 0.55 11.0 4.9 0.26 12.0 0.3 2.4 2 1 1 3 3 3 0 Lectin C-type domain Ricin_B_lectin PF00652.22 OQS01829.1 - 4.9e-20 72.1 17.6 6e-13 49.2 8.9 3.0 1 1 1 3 3 3 3 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.6 OQS01829.1 - 9.7e-10 39.0 11.2 0.00021 21.9 1.2 4.0 2 2 2 4 4 4 3 Ricin-type beta-trefoil lectin domain-like Sugar_tr PF00083.24 OQS01831.1 - 2.9e-26 92.3 5.2 4.2e-26 91.8 5.2 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OQS01831.1 - 6.3e-10 38.5 12.3 1.1e-09 37.7 12.1 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.6 OQS01831.1 - 0.002 16.8 0.5 0.0033 16.0 0.5 1.2 1 0 0 1 1 1 1 MFS/sugar transport protein Sugar_tr PF00083.24 OQS01832.1 - 1.9e-11 43.5 1.6 2.1e-11 43.4 1.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OQS01832.1 - 0.0022 17.0 0.1 0.0024 16.8 0.1 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Mt_ATP-synt_B PF05405.14 OQS01832.1 - 0.025 14.2 0.1 0.028 14.0 0.1 1.1 1 0 0 1 1 1 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) DUF5310 PF17237.2 OQS01832.1 - 0.055 13.3 2.5 0.083 12.8 2.5 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5310) TLC PF03219.14 OQS01832.1 - 0.13 11.0 1.0 0.13 10.9 1.0 1.0 1 0 0 1 1 1 0 TLC ATP/ADP transporter SieB PF14163.6 OQS01832.1 - 0.16 11.5 0.0 0.19 11.2 0.0 1.2 1 0 0 1 1 1 0 Super-infection exclusion protein B Pkinase PF00069.25 OQS01833.1 - 5.8e-50 170.1 0.0 3.4e-49 167.6 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQS01833.1 - 5.9e-47 160.1 0.0 1.1e-45 155.9 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OQS01833.1 - 0.00012 21.0 0.0 0.00021 20.2 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Adeno_E3_CR2 PF02439.15 OQS01833.1 - 0.0031 17.2 0.3 0.006 16.3 0.0 1.6 2 0 0 2 2 2 1 Adenovirus E3 region protein CR2 Kdo PF06293.14 OQS01833.1 - 0.0043 16.4 0.0 0.0086 15.5 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family SKG6 PF08693.10 OQS01833.1 - 0.03 13.7 1.3 0.2 11.1 0.6 2.3 2 0 0 2 2 2 0 Transmembrane alpha-helix domain Kinase-like PF14531.6 OQS01833.1 - 0.051 12.9 0.0 0.1 11.9 0.0 1.4 1 0 0 1 1 1 0 Kinase-like Ank_2 PF12796.7 OQS01834.1 - 4.8e-82 270.6 12.4 1.7e-13 50.9 0.1 7.8 1 1 7 8 8 8 8 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQS01834.1 - 5.5e-73 240.5 23.2 8.9e-11 42.1 0.6 11.1 4 3 8 13 13 13 13 Ankyrin repeats (many copies) Ank PF00023.30 OQS01834.1 - 7.5e-69 225.4 17.9 4.7e-06 26.8 0.1 13.9 13 1 0 13 13 13 12 Ankyrin repeat Ank_3 PF13606.6 OQS01834.1 - 5.3e-64 204.6 11.0 9.3e-05 22.6 0.1 14.0 14 0 0 14 14 14 12 Ankyrin repeat Ank_5 PF13857.6 OQS01834.1 - 2.1e-63 209.5 10.9 4.9e-10 39.5 0.0 11.1 4 3 8 12 12 12 12 Ankyrin repeats (many copies) Gal_Lectin PF02140.18 OQS01835.1 - 2.9e-18 66.1 1.4 2.9e-18 66.1 1.4 2.9 2 0 0 2 2 2 1 Galactose binding lectin domain Pkinase_Tyr PF07714.17 OQS01835.1 - 6.4e-15 55.1 0.0 9e-15 54.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OQS01835.1 - 4.1e-10 39.5 0.0 6.7e-10 38.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain TMEM154 PF15102.6 OQS01835.1 - 9.9e-06 25.5 0.3 2.5e-05 24.2 0.3 1.7 1 0 0 1 1 1 1 TMEM154 protein family DAG1 PF05454.11 OQS01835.1 - 2.9e-05 23.6 0.2 4.9e-05 22.8 0.2 1.3 1 0 0 1 1 1 1 Dystroglycan (Dystrophin-associated glycoprotein 1) SKG6 PF08693.10 OQS01835.1 - 0.00019 20.8 6.2 0.00019 20.8 6.2 1.8 2 0 0 2 2 1 1 Transmembrane alpha-helix domain DUF4448 PF14610.6 OQS01835.1 - 0.00094 19.0 0.1 0.0017 18.2 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) Mid2 PF04478.12 OQS01835.1 - 0.0014 18.5 1.0 0.0027 17.5 1.0 1.5 1 0 0 1 1 1 1 Mid2 like cell wall stress sensor Amnionless PF14828.6 OQS01835.1 - 0.0015 17.4 0.0 0.0022 16.9 0.0 1.2 1 0 0 1 1 1 1 Amnionless ECSCR PF15820.5 OQS01835.1 - 0.0019 18.0 0.9 0.0056 16.5 0.9 1.7 1 0 0 1 1 1 1 Endothelial cell-specific chemotaxis regulator RIFIN PF02009.16 OQS01835.1 - 0.0022 18.0 0.0 0.004 17.1 0.0 1.5 1 0 0 1 1 1 1 Rifin TMEM51 PF15345.6 OQS01835.1 - 0.0029 17.5 0.2 0.0043 16.9 0.2 1.3 1 0 0 1 1 1 1 Transmembrane protein 51 ASFV_J13L PF05568.11 OQS01835.1 - 0.0036 17.1 1.0 0.0036 17.1 1.0 2.4 2 1 0 2 2 2 1 African swine fever virus J13L protein DUF4366 PF14283.6 OQS01835.1 - 0.0054 16.8 0.1 0.017 15.2 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4366) EphA2_TM PF14575.6 OQS01835.1 - 0.0068 17.3 0.1 0.015 16.1 0.1 1.6 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain Orf78 PF06024.12 OQS01835.1 - 0.0076 16.5 0.0 0.017 15.4 0.0 1.5 1 0 0 1 1 1 1 Orf78 (ac78) DUF2561 PF10812.8 OQS01835.1 - 0.0084 16.2 0.0 0.016 15.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2561) Stevor PF17410.2 OQS01835.1 - 0.01 15.4 0.7 0.023 14.3 0.7 1.6 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame CD34_antigen PF06365.12 OQS01835.1 - 0.041 13.5 0.1 0.071 12.7 0.1 1.3 1 0 0 1 1 1 0 CD34/Podocalyxin family Cyt_bd_oxida_II PF02322.15 OQS01835.1 - 0.047 13.0 5.1 0.087 12.2 5.1 1.4 1 0 0 1 1 1 0 Cytochrome bd terminal oxidase subunit II Peptidase_M56 PF05569.11 OQS01835.1 - 0.053 12.7 0.1 0.082 12.1 0.1 1.2 1 0 0 1 1 1 0 BlaR1 peptidase M56 SP_C-Propep PF08999.10 OQS01835.1 - 0.083 12.7 0.0 0.18 11.6 0.0 1.5 1 0 0 1 1 1 0 Surfactant protein C, N terminal propeptide Tmemb_9 PF05434.11 OQS01835.1 - 0.094 12.6 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 TMEM9 DUF5305 PF17231.2 OQS01835.1 - 0.13 11.7 0.6 0.22 10.9 0.6 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5305) Pox_EPC_I2-L1 PF12575.8 OQS01835.1 - 0.17 12.2 3.1 0.47 10.7 3.1 1.8 1 1 0 1 1 1 0 Poxvirus entry protein complex L1 and I2 Adeno_E3_CR2 PF02439.15 OQS01835.1 - 0.21 11.3 6.0 0.42 10.4 6.0 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Pkinase PF00069.25 OQS01836.1 - 7.6e-54 182.8 0.0 9.6e-54 182.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQS01836.1 - 1e-53 182.3 0.0 1.2e-53 182.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pex2_Pex12 PF04757.14 OQS01836.1 - 0.0042 16.7 0.0 0.0062 16.2 0.0 1.2 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region Haspin_kinase PF12330.8 OQS01836.1 - 0.0072 15.3 0.1 0.074 12.0 0.0 2.0 2 0 0 2 2 2 1 Haspin like kinase domain APH PF01636.23 OQS01836.1 - 0.016 15.1 0.0 0.04 13.8 0.0 1.6 1 1 1 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.14 OQS01836.1 - 0.021 14.2 0.0 0.033 13.5 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PRIMA1 PF16101.5 OQS01836.1 - 0.081 13.0 0.1 0.19 11.8 0.1 1.6 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 Pkinase_fungal PF17667.1 OQS01836.1 - 0.086 11.6 0.0 0.12 11.1 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Syndecan PF01034.20 OQS01836.1 - 0.18 11.7 0.7 0.34 10.8 0.7 1.4 1 0 0 1 1 1 0 Syndecan domain NAD_binding_1 PF00175.21 OQS01837.1 - 0.033 14.8 0.0 0.062 14.0 0.0 1.5 1 0 0 1 1 1 0 Oxidoreductase NAD-binding domain FliG_M PF14841.6 OQS01838.1 - 0.024 14.8 0.0 0.14 12.4 0.0 1.9 2 0 0 2 2 2 0 FliG middle domain PfkB PF00294.24 OQS01839.1 - 1.1e-69 235.0 0.2 1.4e-69 234.7 0.2 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase DDE_Tnp_4 PF13359.6 OQS01840.1 - 7e-06 25.8 0.0 9e-06 25.4 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 OQS01840.1 - 0.0014 18.3 0.0 0.0018 18.0 0.0 1.1 1 0 0 1 1 1 1 Plant transposon protein DUF2475 PF10629.9 OQS01841.1 - 0.01 16.1 0.4 1.9 8.7 0.0 2.9 3 0 0 3 3 3 2 Protein of unknown function (DUF2475) HTH_33 PF13592.6 OQS01842.1 - 0.019 14.6 0.2 0.2 11.3 0.0 2.2 2 0 0 2 2 2 0 Winged helix-turn helix HTH_ABP1_N PF18107.1 OQS01842.1 - 0.1 12.3 0.0 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 Fission yeast centromere protein N-terminal domain HTH_Tnp_Tc3_2 PF01498.18 OQS01842.1 - 0.11 12.7 0.1 0.17 12.1 0.1 1.2 1 0 0 1 1 1 0 Transposase AMP-binding PF00501.28 OQS01843.1 - 1.2e-77 261.3 0.0 1.9e-77 260.6 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 OQS01843.1 - 8.4e-16 58.7 0.2 3e-15 57.0 0.2 2.0 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain AMP-binding PF00501.28 OQS01844.1 - 1.7e-80 270.7 0.0 2.2e-80 270.3 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 OQS01844.1 - 3.1e-10 40.9 0.0 1.4e-09 38.8 0.0 2.2 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Pkinase PF00069.25 OQS01845.1 - 3.5e-46 157.7 0.0 4.3e-46 157.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQS01845.1 - 8e-26 90.9 0.0 9.8e-26 90.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OQS01845.1 - 4.2e-09 36.1 0.0 6.6e-06 25.7 0.0 2.1 2 0 0 2 2 2 2 Kinase-like APH PF01636.23 OQS01845.1 - 0.0013 18.7 0.1 0.0027 17.7 0.1 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family QueF PF14489.6 OQS01845.1 - 0.1 12.8 0.0 0.23 11.6 0.0 1.5 1 0 0 1 1 1 0 QueF-like protein BT1 PF03092.16 OQS01846.1 - 9.8e-09 34.0 17.0 5.9e-07 28.1 7.9 3.2 2 1 0 2 2 2 2 BT1 family Pkinase PF00069.25 OQS01847.1 - 1.3e-56 191.9 0.0 2.3e-56 191.1 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Cyclin_N PF00134.23 OQS01847.1 - 2.4e-24 85.5 0.5 4.4e-24 84.6 0.5 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Pkinase_Tyr PF07714.17 OQS01847.1 - 1.3e-15 57.4 0.0 2.1e-15 56.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase F-box-like PF12937.7 OQS01847.1 - 3.5e-09 36.4 0.0 5.4e-08 32.6 0.0 2.5 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 OQS01847.1 - 0.0011 18.8 0.2 0.0033 17.3 0.1 1.9 2 0 0 2 2 2 1 F-box domain Kdo PF06293.14 OQS01847.1 - 0.011 15.2 0.3 0.022 14.1 0.1 1.6 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family TRP PF06011.12 OQS01848.1 - 3.4e-12 45.8 22.3 6.3e-12 44.9 21.5 1.7 2 0 0 2 2 2 1 Transient receptor potential (TRP) ion channel DUF4083 PF13314.6 OQS01848.1 - 0.046 13.7 0.1 0.046 13.7 0.1 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4083) DUF5056 PF16479.5 OQS01848.1 - 0.22 11.8 0.1 0.22 11.8 0.1 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF5056) DUF1980 PF09323.10 OQS01848.1 - 1.2 9.0 0.0 1.2 9.0 0.0 3.2 3 1 1 4 4 4 0 Domain of unknown function (DUF1980) Insulin_TMD PF17870.1 OQS01848.1 - 5.9 7.0 11.7 17 5.5 0.0 3.9 3 0 0 3 3 3 0 Insulin receptor trans-membrane segment Pkinase_Tyr PF07714.17 OQS01851.1 - 4e-47 160.7 0.0 6.2e-47 160.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OQS01851.1 - 6.3e-44 150.3 0.0 1.3e-43 149.3 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Ank_2 PF12796.7 OQS01851.1 - 8.8e-14 51.9 4.7 4.5e-09 36.8 0.4 2.5 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OQS01851.1 - 1.3e-10 40.5 0.6 0.023 15.2 0.0 4.4 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.6 OQS01851.1 - 1.8e-09 37.7 1.3 0.012 15.9 0.0 3.9 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 OQS01851.1 - 2.4e-08 34.0 1.3 0.031 14.7 0.1 4.0 2 1 1 3 3 3 3 Ankyrin repeat Ank_4 PF13637.6 OQS01851.1 - 8.5e-07 29.4 2.1 0.038 14.6 0.1 4.6 3 2 1 4 4 4 2 Ankyrin repeats (many copies) Haspin_kinase PF12330.8 OQS01851.1 - 0.011 14.8 0.1 0.32 9.9 0.1 2.5 1 1 0 1 1 1 0 Haspin like kinase domain CAS_CSE1 PF03378.15 OQS01851.1 - 0.11 11.0 0.8 1.3 7.4 0.7 2.0 2 0 0 2 2 2 0 CAS/CSE protein, C-terminus DDE_3 PF13358.6 OQS01852.1 - 2e-10 40.6 0.0 2.4e-10 40.4 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease Acetyltransf_9 PF13527.7 OQS01853.1 - 0.0011 19.0 0.1 0.0022 18.1 0.1 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_15 PF17013.5 OQS01853.1 - 0.0013 18.3 0.0 0.0018 17.8 0.0 1.2 1 0 0 1 1 1 1 Putative acetyl-transferase Acetyltransf_1 PF00583.25 OQS01853.1 - 0.004 17.4 0.1 0.02 15.1 0.0 2.1 2 1 0 2 2 2 1 Acetyltransferase (GNAT) family FR47 PF08445.10 OQS01853.1 - 0.11 12.5 0.0 0.23 11.4 0.0 1.5 1 0 0 1 1 1 0 FR47-like protein MFS_1 PF07690.16 OQS01854.1 - 0.00051 19.1 0.5 0.00055 19.0 0.5 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Elicitin PF00964.17 OQS01854.1 - 0.016 15.3 0.9 0.026 14.6 0.9 1.3 1 0 0 1 1 1 0 Elicitin TACC_C PF05010.14 OQS01855.1 - 0.0067 16.2 29.3 0.0067 16.2 29.3 8.4 2 2 6 8 8 8 2 Transforming acidic coiled-coil-containing protein (TACC), C-terminal Pox_A_type_inc PF04508.12 OQS01855.1 - 0.58 10.1 0.0 0.58 10.1 0.0 4.3 5 0 0 5 5 5 0 Viral A-type inclusion protein repeat DUF4457 PF14652.6 OQS01857.1 - 2.2e-128 428.1 0.0 2e-85 286.9 0.0 3.7 2 1 0 2 2 2 2 Domain of unknown function (DUF4457) Peptidase_C1_2 PF03051.15 OQS01857.1 - 4e-95 319.2 0.2 6.4e-95 318.5 0.2 1.3 1 0 0 1 1 1 1 Peptidase C1-like family PTR PF12789.7 OQS01857.1 - 0.0013 18.7 0.3 0.0041 17.1 0.3 1.8 1 0 0 1 1 1 1 Phage tail repeat like DUF4795 PF16043.5 OQS01857.1 - 0.0025 17.4 5.4 0.03 13.9 5.4 2.6 1 1 0 1 1 1 1 Domain of unknown function (DUF4795) Sad1_UNC PF07738.13 OQS01857.1 - 0.0043 17.1 0.0 1.9 8.5 0.0 3.7 4 0 0 4 4 4 1 Sad1 / UNC-like C-terminal DUF445 PF04286.12 OQS01857.1 - 0.071 12.9 2.6 0.15 11.9 2.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF445) ApoLp-III PF07464.11 OQS01857.1 - 0.17 11.9 9.3 0.38 10.8 9.3 1.6 1 0 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) Fzo_mitofusin PF04799.13 OQS01857.1 - 0.44 10.1 6.8 0.72 9.4 5.6 1.9 1 1 1 2 2 2 0 fzo-like conserved region Caskin-Pro-rich PF16907.5 OQS01857.1 - 0.99 10.0 5.6 7.4 7.2 0.2 2.5 2 0 0 2 2 2 0 Proline rich region of Caskin proteins PAN_4 PF14295.6 OQS01858.1 - 3.1e-63 209.5 78.8 7.4e-09 35.4 1.5 9.6 9 0 0 9 9 9 9 PAN domain PAN_1 PF00024.26 OQS01858.1 - 1.6e-42 143.3 64.0 4.5e-05 23.3 2.0 11.3 8 3 3 11 11 11 10 PAN domain Acyl-CoA_ox_N PF14749.6 OQS01858.1 - 1.3e-21 77.5 0.2 2.2e-21 76.7 0.2 1.4 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_M PF02770.19 OQS01858.1 - 1.1e-13 51.1 0.0 2.8e-13 49.9 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain PIG-L PF02585.17 OQS01858.1 - 1.2e-05 26.0 0.0 2.5e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 GlcNAc-PI de-N-acetylase PAN_2 PF08276.11 OQS01858.1 - 0.052 13.7 69.4 0.065 13.4 2.3 9.9 9 0 0 9 9 9 0 PAN-like domain MCU PF04678.13 OQS01859.1 - 1.8e-26 93.3 3.1 4.9e-26 91.9 3.1 1.8 1 1 0 1 1 1 1 Mitochondrial calcium uniporter COR PF16095.5 OQS01859.1 - 9.8e-05 22.2 0.0 0.00018 21.3 0.0 1.4 1 0 0 1 1 1 1 C-terminal of Roc, COR, domain 2OG-FeII_Oxy_3 PF13640.6 OQS01861.1 - 9.6e-12 45.6 0.2 1.5e-11 45.0 0.2 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.20 OQS01861.1 - 2.1e-05 24.9 0.1 4.5e-05 23.9 0.1 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily RALF PF05498.11 OQS01861.1 - 0.032 15.2 0.1 0.055 14.4 0.1 1.4 1 0 0 1 1 1 0 Rapid ALkalinization Factor (RALF) TMCCDC2 PF15844.5 OQS01861.1 - 0.1 12.5 0.0 0.16 11.9 0.0 1.2 1 0 0 1 1 1 0 Transmembrane and coiled-coil domain-containing protein 2 FGE-sulfatase PF03781.16 OQS01863.1 - 1.2e-19 70.9 0.7 1.1e-09 38.2 0.0 2.2 2 0 0 2 2 2 2 Sulfatase-modifying factor enzyme 1 Methyltransf_33 PF10017.9 OQS01863.1 - 5.7e-08 32.3 0.0 9.2e-08 31.6 0.0 1.2 1 0 0 1 1 1 1 Histidine-specific methyltransferase, SAM-dependent DinB_2 PF12867.7 OQS01863.1 - 1.4e-05 25.6 0.2 8.2e-05 23.1 0.2 2.2 1 1 0 1 1 1 1 DinB superfamily IQ PF00612.27 OQS01864.1 - 0.00017 21.1 8.2 0.21 11.5 0.2 5.2 4 0 0 4 4 4 3 IQ calmodulin-binding motif PRKG1_interact PF15898.5 OQS01867.1 - 0.051 14.5 0.1 0.063 14.2 0.1 1.1 1 0 0 1 1 1 0 cGMP-dependent protein kinase interacting domain Nop10p PF04135.12 OQS01868.1 - 1.3e-22 79.6 1.0 1.8e-22 79.1 1.0 1.2 1 0 0 1 1 1 1 Nucleolar RNA-binding protein, Nop10p family Filo_glycop PF01611.16 OQS01868.1 - 0.089 11.7 0.0 0.096 11.6 0.0 1.1 1 0 0 1 1 1 0 Filovirus glycoprotein Ank_2 PF12796.7 OQS01869.1 - 9.1e-49 164.0 3.9 8.7e-15 55.1 0.1 5.9 1 1 2 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQS01869.1 - 3.5e-39 132.7 3.1 3.7e-08 33.7 0.2 7.7 5 2 2 7 7 6 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQS01869.1 - 8.4e-38 124.1 13.1 0.00013 22.1 0.0 11.9 11 0 0 11 11 11 7 Ankyrin repeat Ank PF00023.30 OQS01869.1 - 6.3e-31 105.5 19.0 0.00013 22.3 0.5 11.4 11 1 0 11 11 10 6 Ankyrin repeat Ank_5 PF13857.6 OQS01869.1 - 7.6e-30 102.6 7.2 7.4e-08 32.5 0.4 9.0 3 1 7 11 11 10 7 Ankyrin repeats (many copies) ANAPC3 PF12895.7 OQS01869.1 - 0.061 13.6 1.2 0.2 11.9 1.2 2.0 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.6 OQS01869.1 - 0.073 13.4 0.8 1.8 8.9 0.1 2.6 1 1 0 1 1 1 0 Tetratricopeptide repeat TPR_2 PF07719.17 OQS01869.1 - 0.083 13.1 1.1 0.37 11.0 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.28 OQS01869.1 - 0.12 12.2 0.1 0.29 11.0 0.1 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat THOC7 PF05615.13 OQS01869.1 - 0.13 12.5 14.9 0.13 12.5 5.9 2.8 2 1 1 3 3 3 0 Tho complex subunit 7 TPR_7 PF13176.6 OQS01869.1 - 0.18 11.9 0.7 1.1 9.4 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat FlxA PF14282.6 OQS01869.1 - 0.21 11.6 14.6 1.6 8.7 1.6 2.4 2 0 0 2 2 2 0 FlxA-like protein AAA_13 PF13166.6 OQS01869.1 - 0.67 8.5 14.8 1.1 7.8 14.8 1.2 1 0 0 1 1 1 0 AAA domain Filament PF00038.21 OQS01869.1 - 0.69 9.4 22.8 1.5 8.3 11.7 2.2 1 1 1 2 2 2 0 Intermediate filament protein DUF1664 PF07889.12 OQS01869.1 - 0.71 9.9 8.2 0.19 11.8 0.8 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) ATG16 PF08614.11 OQS01869.1 - 0.74 10.0 17.5 0.22 11.7 3.6 2.6 1 1 0 2 2 2 0 Autophagy protein 16 (ATG16) NPV_P10 PF05531.12 OQS01869.1 - 1 9.9 7.3 4 8.0 0.4 2.8 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Spc7 PF08317.11 OQS01869.1 - 2.4 7.0 21.7 1.7 7.5 6.8 2.2 1 1 1 2 2 2 0 Spc7 kinetochore protein TMF_TATA_bd PF12325.8 OQS01869.1 - 3.9 7.7 17.7 1.7 8.9 0.4 3.2 2 1 1 3 3 3 0 TATA element modulatory factor 1 TATA binding Filo_VP24 PF06389.11 OQS01871.1 - 0.036 13.6 0.1 0.057 12.9 0.1 1.3 1 0 0 1 1 1 0 Filovirus membrane-associated protein VP24 Plant_NMP1 PF06694.11 OQS01871.1 - 0.054 12.6 0.4 0.074 12.1 0.4 1.1 1 0 0 1 1 1 0 Plant nuclear matrix protein 1 (NMP1) DUF1192 PF06698.11 OQS01871.1 - 0.4 10.8 2.3 16 5.6 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) LRR_4 PF12799.7 OQS01872.1 - 2.3e-06 27.8 9.6 0.00018 21.8 1.1 4.2 1 1 3 4 4 4 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 OQS01872.1 - 0.00023 20.9 7.4 0.00026 20.7 3.9 2.7 2 1 0 2 2 2 1 Leucine rich repeat EF-hand_9 PF14658.6 OQS01872.1 - 0.0067 16.7 0.3 0.039 14.3 0.0 2.5 3 0 0 3 3 3 1 EF-hand domain LRR_1 PF00560.33 OQS01872.1 - 0.019 15.5 5.4 5 8.1 0.2 4.0 3 0 0 3 3 3 0 Leucine Rich Repeat Ndc80_HEC PF03801.13 OQS01872.1 - 0.035 13.7 0.3 0.083 12.5 0.1 1.7 2 0 0 2 2 2 0 HEC/Ndc80p family EF-hand_7 PF13499.6 OQS01872.1 - 0.052 14.0 0.1 0.37 11.3 0.0 2.5 2 0 0 2 2 2 0 EF-hand domain pair Rootletin PF15035.6 OQS01872.1 - 0.11 12.5 3.8 0.068 13.2 0.6 2.1 2 0 0 2 2 2 0 Ciliary rootlet component, centrosome cohesion OTU PF02338.19 OQS01873.1 - 1.5e-18 67.5 0.0 3.9e-18 66.2 0.0 1.7 1 0 0 1 1 1 1 OTU-like cysteine protease Peptidase_C65 PF10275.9 OQS01873.1 - 0.0029 17.1 1.2 0.98 8.8 0.8 2.8 2 1 0 2 2 2 2 Peptidase C65 Otubain CENP-F_leu_zip PF10473.9 OQS01873.1 - 0.02 14.9 1.3 0.02 14.9 1.3 2.3 3 0 0 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Armet PF10208.9 OQS01873.1 - 0.026 14.5 0.1 0.1 12.5 0.0 2.0 1 1 1 2 2 2 0 Degradation arginine-rich protein for mis-folding DUF1192 PF06698.11 OQS01873.1 - 2.6 8.2 5.9 11 6.1 0.4 2.9 3 1 0 3 3 3 0 Protein of unknown function (DUF1192) YccJ PF13993.6 OQS01874.1 - 0.068 13.5 0.1 0.098 13.0 0.1 1.3 1 0 0 1 1 1 0 YccJ-like protein Clr5 PF14420.6 OQS01875.1 - 0.25 11.6 2.9 2.3 8.5 0.7 2.8 2 0 0 2 2 2 0 Clr5 domain ABC_membrane PF00664.23 OQS01876.1 - 3.4e-31 108.9 24.0 4.9e-31 108.4 24.0 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 OQS01876.1 - 1.6e-30 106.4 0.0 3.1e-30 105.5 0.0 1.5 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 OQS01876.1 - 3.3e-06 26.7 0.5 0.036 13.5 0.0 2.2 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 OQS01876.1 - 0.0025 17.9 0.0 0.0054 16.8 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_21 PF13304.6 OQS01876.1 - 0.0071 16.2 0.0 0.28 10.9 0.0 2.3 1 1 1 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 OQS01876.1 - 0.0082 15.9 0.4 0.022 14.5 0.1 1.9 2 0 0 2 2 2 1 P-loop containing region of AAA domain DUF87 PF01935.17 OQS01876.1 - 0.016 15.3 0.1 0.034 14.2 0.1 1.6 1 0 0 1 1 1 0 Helicase HerA, central domain ATP-synt_ab PF00006.25 OQS01876.1 - 0.028 14.1 0.0 0.56 9.8 0.0 2.3 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_23 PF13476.6 OQS01876.1 - 0.035 14.6 1.1 0.037 14.5 0.0 1.6 2 0 0 2 2 1 0 AAA domain AAA_22 PF13401.6 OQS01876.1 - 0.035 14.4 0.0 0.099 12.9 0.0 1.7 1 1 0 1 1 1 0 AAA domain DEAD PF00270.29 OQS01876.1 - 0.069 12.9 0.3 11 5.7 0.0 2.4 2 0 0 2 2 2 0 DEAD/DEAH box helicase AAA_16 PF13191.6 OQS01876.1 - 0.13 12.7 0.0 0.27 11.6 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain RGS PF00615.19 OQS01877.1 - 5.9e-35 120.1 1.5 1.8e-18 66.9 0.1 3.2 3 0 0 3 3 3 3 Regulator of G protein signaling domain RGS-like PF09128.11 OQS01877.1 - 7e-06 25.9 0.7 0.11 12.2 0.1 2.2 2 0 0 2 2 2 2 Regulator of G protein signalling-like domain TPR_2 PF07719.17 OQS01878.1 - 1.5e-16 59.1 8.3 0.072 13.2 0.1 6.7 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_1 PF00515.28 OQS01878.1 - 1.6e-15 56.2 7.6 0.051 13.4 0.5 6.4 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_12 PF13424.6 OQS01878.1 - 2.2e-13 50.3 6.3 7e-05 23.0 0.0 5.0 5 0 0 5 5 5 3 Tetratricopeptide repeat Methyltransf_11 PF08241.12 OQS01878.1 - 2.3e-12 47.4 0.0 7e-12 45.8 0.0 1.9 2 0 0 2 2 1 1 Methyltransferase domain TPR_8 PF13181.6 OQS01878.1 - 6.7e-12 44.6 8.7 0.23 11.8 0.9 5.7 5 0 0 5 5 5 3 Tetratricopeptide repeat Methyltransf_12 PF08242.12 OQS01878.1 - 1.5e-10 41.7 0.0 4.4e-10 40.2 0.0 1.8 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OQS01878.1 - 1.7e-10 41.5 0.0 5.8e-10 39.7 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain TPR_7 PF13176.6 OQS01878.1 - 2.1e-09 36.8 4.9 0.74 10.0 0.1 6.3 6 0 0 6 6 6 2 Tetratricopeptide repeat Methyltransf_31 PF13847.6 OQS01878.1 - 2.9e-07 30.4 0.0 6e-07 29.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain TPR_16 PF13432.6 OQS01878.1 - 1.1e-06 29.2 10.3 0.0001 22.9 0.1 4.6 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_6 PF13174.6 OQS01878.1 - 2.3e-06 27.9 3.9 9.5 7.1 0.1 5.5 5 0 0 5 5 5 0 Tetratricopeptide repeat Methyltransf_23 PF13489.6 OQS01878.1 - 5e-06 26.5 0.0 1.3e-05 25.1 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain ANAPC3 PF12895.7 OQS01878.1 - 2e-05 24.7 6.1 0.0046 17.1 0.4 3.6 3 0 0 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.6 OQS01878.1 - 3.9e-05 23.7 3.5 4.2 8.0 0.1 5.4 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_11 PF13414.6 OQS01878.1 - 5.2e-05 22.9 7.9 0.38 10.5 0.1 5.4 4 1 1 5 5 5 1 TPR repeat TPR_14 PF13428.6 OQS01878.1 - 0.00011 22.7 10.7 1.5 9.9 0.1 6.2 5 2 2 7 7 5 1 Tetratricopeptide repeat TPR_19 PF14559.6 OQS01878.1 - 0.00012 22.5 8.9 0.13 12.8 0.5 4.3 3 1 1 4 4 4 1 Tetratricopeptide repeat Glyco_hydro_44 PF12891.7 OQS01878.1 - 0.023 14.6 0.0 0.043 13.7 0.0 1.3 1 0 0 1 1 1 0 Glycoside hydrolase family 44 SNAP PF14938.6 OQS01878.1 - 0.06 12.8 2.3 0.12 11.8 0.6 2.2 1 1 0 1 1 1 0 Soluble NSF attachment protein, SNAP Ubie_methyltran PF01209.18 OQS01878.1 - 0.062 12.6 0.0 0.1 11.9 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family PrmA PF06325.13 OQS01878.1 - 0.074 12.4 0.0 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) TPR_10 PF13374.6 OQS01878.1 - 0.14 12.1 8.7 33 4.5 0.0 5.4 6 0 0 6 6 6 0 Tetratricopeptide repeat BTAD PF03704.17 OQS01878.1 - 0.4 11.1 3.0 0.99 9.8 0.1 2.7 3 0 0 3 3 2 0 Bacterial transcriptional activator domain TPR_3 PF07720.12 OQS01878.1 - 1.5 8.9 8.9 1.4 8.9 1.2 3.4 3 0 0 3 3 2 0 Tetratricopeptide repeat Ribosomal_L29 PF00831.23 OQS01880.1 - 1.1e-16 60.5 3.7 1.1e-15 57.3 0.1 2.3 2 0 0 2 2 2 2 Ribosomal L29 protein DUF4407 PF14362.6 OQS01880.1 - 0.042 13.2 3.1 0.093 12.1 3.1 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Macro PF01661.21 OQS01881.1 - 1.9e-12 47.3 0.0 2.9e-12 46.7 0.0 1.3 1 0 0 1 1 1 1 Macro domain Trimer_CC PF08954.11 OQS01883.1 - 0.26 10.9 10.8 0.098 12.2 1.1 2.9 3 0 0 3 3 3 0 Trimerisation motif DUF1168 PF06658.12 OQS01883.1 - 2.1 8.2 5.7 3.3 7.5 5.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1168) CCDC-167 PF15188.6 OQS01883.1 - 3.6 8.0 6.3 8.8 6.8 6.3 1.7 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 167 DASH_Spc19 PF08287.11 OQS01883.1 - 8.1 6.3 13.6 3.4 7.5 8.7 2.4 3 0 0 3 3 3 0 Spc19 Tim17 PF02466.19 OQS01884.1 - 1.1e-09 38.6 2.0 1.4e-09 38.3 2.0 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Cation_efflux PF01545.21 OQS01884.1 - 0.028 14.1 0.1 0.035 13.8 0.1 1.2 1 0 0 1 1 1 0 Cation efflux family Romo1 PF10247.9 OQS01884.1 - 0.13 12.6 3.8 0.26 11.7 2.4 2.0 1 1 1 2 2 2 0 Reactive mitochondrial oxygen species modulator 1 RWP-RK PF02042.15 OQS01885.1 - 3.3e-20 71.8 0.7 5.8e-20 71.0 0.1 1.7 2 0 0 2 2 2 1 RWP-RK domain BBP1_C PF15272.6 OQS01885.1 - 0.078 12.8 0.5 0.11 12.3 0.5 1.2 1 0 0 1 1 1 0 Spindle pole body component BBP1, C-terminal p450 PF00067.22 OQS01890.1 - 1.8e-36 125.9 0.0 2.3e-36 125.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Sacchrp_dh_NADP PF03435.18 OQS01890.1 - 0.026 14.8 0.0 0.042 14.1 0.0 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain DNA_pol_B_2 PF03175.13 OQS01891.1 - 1.9e-08 33.6 0.0 3e-08 33.0 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral Dopey_N PF04118.14 OQS01893.1 - 0.016 14.4 0.0 0.018 14.2 0.0 1.2 1 0 0 1 1 1 0 Dopey, N-terminal Glyco_hydro_cc PF11790.8 OQS01893.1 - 0.018 14.6 0.0 5.4 6.5 0.0 2.1 1 1 1 2 2 2 0 Glycosyl hydrolase catalytic core DUF2791 PF10923.8 OQS01893.1 - 0.11 11.4 0.0 0.15 10.9 0.0 1.2 1 0 0 1 1 1 0 P-loop Domain of unknown function (DUF2791) Rhodanese_C PF12368.8 OQS01894.1 - 3.7e-12 46.4 6.4 3.7e-12 46.4 6.4 2.6 3 0 0 3 3 3 1 Rhodanase C-terminal Rhodanese PF00581.20 OQS01894.1 - 9.7e-11 42.1 0.0 1.6e-10 41.5 0.0 1.4 1 0 0 1 1 1 1 Rhodanese-like domain FYVE PF01363.21 OQS01894.1 - 0.16 12.1 0.5 0.16 12.1 0.5 2.7 3 1 0 3 3 3 0 FYVE zinc finger FlxA PF14282.6 OQS01894.1 - 0.23 11.5 2.1 0.19 11.7 0.8 1.4 2 0 0 2 2 2 0 FlxA-like protein RNA_POL_M_15KD PF02150.16 OQS01894.1 - 0.27 11.1 3.5 0.42 10.5 0.1 2.8 3 0 0 3 3 3 0 RNA polymerases M/15 Kd subunit FYVE_2 PF02318.16 OQS01894.1 - 1.8 8.8 12.0 0.56 10.4 2.8 2.7 3 0 0 3 3 3 0 FYVE-type zinc finger DAHP_synth_2 PF01474.16 OQS01895.1 - 2.6e-121 405.2 0.0 2.8e-94 316.1 0.0 2.0 2 0 0 2 2 2 2 Class-II DAHP synthetase family Pkinase PF00069.25 OQS01896.1 - 1e-46 159.4 0.0 1.2e-46 159.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQS01896.1 - 5.3e-25 88.2 0.0 6.1e-25 88.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OQS01896.1 - 2.2e-05 23.9 0.0 4.1e-05 23.0 0.0 1.3 1 1 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 OQS01896.1 - 0.0011 17.9 0.2 0.0014 17.6 0.2 1.1 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 OQS01896.1 - 0.0017 17.8 0.4 0.0028 17.0 0.4 1.4 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Acetyltransf_10 PF13673.7 OQS01898.1 - 1e-15 57.8 0.0 1.1e-15 57.6 0.0 1.0 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 OQS01898.1 - 1.8e-07 31.4 0.0 2.1e-07 31.2 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 OQS01898.1 - 0.00018 21.7 0.0 0.00021 21.5 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.7 OQS01898.1 - 0.0023 18.0 0.0 0.0028 17.8 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 OQS01898.1 - 0.073 13.0 0.0 0.12 12.3 0.0 1.3 1 1 0 1 1 1 0 FR47-like protein PhzC-PhzF PF02567.16 OQS01899.1 - 1.9e-33 116.2 0.1 5.2e-27 95.0 0.0 2.0 1 1 1 2 2 2 2 Phenazine biosynthesis-like protein DWNN PF08783.11 OQS01900.1 - 0.0073 16.6 0.1 0.027 14.8 0.1 1.9 1 0 0 1 1 1 1 DWNN domain AAA_22 PF13401.6 OQS01900.1 - 0.13 12.5 0.0 2 8.7 0.0 2.4 1 1 0 1 1 1 0 AAA domain Arm PF00514.23 OQS01901.1 - 1.8e-15 56.4 50.8 0.0025 17.8 0.1 19.7 23 0 0 23 23 23 5 Armadillo/beta-catenin-like repeat Arm_2 PF04826.13 OQS01901.1 - 0.00058 19.4 37.8 0.039 13.4 3.3 8.4 8 1 1 9 9 9 3 Armadillo-like HEAT_EZ PF13513.6 OQS01901.1 - 0.0011 19.4 12.9 0.053 14.1 0.0 6.3 6 0 0 6 6 6 2 HEAT-like repeat HEAT_2 PF13646.6 OQS01901.1 - 0.006 16.9 6.6 0.29 11.6 0.0 6.7 8 1 0 8 8 8 1 HEAT repeats HEAT PF02985.22 OQS01901.1 - 0.2 12.0 0.0 0.2 12.0 0.0 10.0 13 0 0 13 13 13 0 HEAT repeat LRR_8 PF13855.6 OQS01902.1 - 1.7e-11 43.7 5.0 3.2e-11 42.8 2.3 2.5 3 0 0 3 3 3 1 Leucine rich repeat LRR_4 PF12799.7 OQS01902.1 - 6.4e-11 42.3 13.1 1e-05 25.8 1.8 3.2 1 1 3 4 4 4 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 OQS01902.1 - 1.6e-05 24.8 2.7 2.7 8.9 0.0 4.3 3 1 0 3 3 3 3 Leucine Rich Repeat LRR_6 PF13516.6 OQS01902.1 - 0.0031 17.4 2.2 1.2 9.4 0.1 3.2 4 0 0 4 4 4 2 Leucine Rich repeat Suppressor_P21 PF11479.8 OQS01902.1 - 0.13 12.5 0.3 23 5.3 0.1 2.4 1 1 1 2 2 2 0 RNA silencing suppressor P21 C-terminal domain TYW3 PF02676.14 OQS01903.1 - 6.3e-56 189.1 0.0 8.8e-56 188.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase TYW3 Kelch_4 PF13418.6 OQS01903.1 - 1.1e-23 82.9 0.2 6.6e-07 29.2 0.0 5.6 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_6 PF13964.6 OQS01903.1 - 1e-19 70.0 3.6 0.00016 21.8 0.2 5.2 3 1 2 5 5 5 4 Kelch motif Kelch_5 PF13854.6 OQS01903.1 - 5.9e-19 67.6 0.0 6.4e-08 32.4 0.0 4.5 4 0 0 4 4 4 3 Kelch motif Kelch_1 PF01344.25 OQS01903.1 - 7.4e-19 67.1 0.0 8.4e-07 28.5 0.0 3.8 4 0 0 4 4 4 3 Kelch motif Kelch_2 PF07646.15 OQS01903.1 - 9.7e-15 53.9 2.7 0.0013 18.6 0.2 4.9 5 0 0 5 5 5 3 Kelch motif Kelch_3 PF13415.6 OQS01903.1 - 2.8e-14 53.0 0.2 0.022 15.0 0.0 4.8 5 0 0 5 5 5 4 Galactose oxidase, central domain cNMP_binding PF00027.29 OQS01904.1 - 3.7e-34 116.7 0.1 3.5e-15 55.8 0.0 3.5 3 0 0 3 3 3 3 Cyclic nucleotide-binding domain DUF1447 PF07288.11 OQS01904.1 - 0.098 12.7 0.5 0.5 10.5 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1447) Coatomer_WDAD PF04053.14 OQS01905.1 - 2.4e-149 498.2 0.0 1.6e-148 495.5 0.0 2.1 2 0 0 2 2 2 1 Coatomer WD associated region WD40 PF00400.32 OQS01905.1 - 1.1e-27 95.7 10.8 5.4e-07 30.2 0.1 7.8 8 0 0 8 8 8 5 WD domain, G-beta repeat BBS2_Mid PF14783.6 OQS01905.1 - 0.01 15.9 0.0 21 5.2 0.0 3.9 3 1 0 3 3 3 0 Ciliary BBSome complex subunit 2, middle region Nup160 PF11715.8 OQS01905.1 - 0.013 14.2 0.1 1.6 7.3 0.0 2.9 3 0 0 3 3 3 0 Nucleoporin Nup120/160 MetallophosC PF16370.5 OQS01905.1 - 0.066 13.4 0.1 0.32 11.2 0.1 2.2 1 0 0 1 1 1 0 C terminal of Calcineurin-like phosphoesterase DUF3623 PF12291.8 OQS01905.1 - 0.15 11.2 0.0 0.29 10.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3623) TP2 PF01254.18 OQS01905.1 - 0.19 12.3 1.7 0.36 11.4 1.4 1.6 1 1 0 1 1 1 0 Nuclear transition protein 2 TFIIA PF03153.13 OQS01905.1 - 0.27 11.2 28.5 0.39 10.6 28.5 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit STOP PF05217.12 OQS01906.1 - 0.15 12.4 0.0 0.31 11.4 0.0 1.5 1 0 0 1 1 1 0 STOP protein TPR_MLP1_2 PF07926.12 OQS01907.1 - 0.00038 20.5 17.2 0.00038 20.5 17.2 8.2 2 1 3 7 7 7 1 TPR/MLP1/MLP2-like protein CCDC144C PF14915.6 OQS01907.1 - 0.003 16.7 17.5 0.003 16.7 17.5 5.7 3 1 3 6 6 6 2 CCDC144C protein coiled-coil region CENP-F_leu_zip PF10473.9 OQS01907.1 - 0.003 17.6 10.5 0.003 17.6 10.5 7.6 1 1 6 8 8 7 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DivIC PF04977.15 OQS01907.1 - 0.0038 17.0 1.1 0.0038 17.0 1.1 12.1 6 3 5 13 13 13 3 Septum formation initiator DUF1664 PF07889.12 OQS01907.1 - 0.0048 16.9 2.7 0.0048 16.9 2.7 8.0 4 2 4 8 8 8 2 Protein of unknown function (DUF1664) Fez1 PF06818.15 OQS01907.1 - 0.0056 17.2 13.8 0.0056 17.2 13.8 6.5 1 1 4 5 5 4 2 Fez1 SlyX PF04102.12 OQS01907.1 - 0.0088 16.6 2.8 0.0088 16.6 2.8 10.8 5 4 4 10 10 9 1 SlyX M20_dimer PF07687.14 OQS01907.1 - 0.017 15.1 1.1 0.11 12.4 0.2 2.7 2 0 0 2 2 2 0 Peptidase dimerisation domain Spc7 PF08317.11 OQS01907.1 - 0.018 13.9 104.2 0.011 14.6 7.6 6.1 1 1 5 6 6 6 0 Spc7 kinetochore protein Ig_5 PF16681.5 OQS01907.1 - 0.58 10.6 3.7 0.52 10.8 0.5 2.6 2 0 0 2 2 2 0 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain MAD PF05557.13 OQS01907.1 - 0.68 8.2 103.1 0.22 9.8 22.3 4.9 1 1 4 5 5 5 0 Mitotic checkpoint protein E2R135 PF11570.8 OQS01907.1 - 0.7 10.2 25.4 0.26 11.6 2.7 5.4 3 3 2 5 5 5 0 Coiled-coil receptor-binding R-domain of colicin E2 ADIP PF11559.8 OQS01907.1 - 0.9 9.6 108.1 0.046 13.8 11.0 8.3 2 1 3 8 8 7 0 Afadin- and alpha -actinin-Binding ATG16 PF08614.11 OQS01907.1 - 1.3 9.2 111.9 0.1 12.8 14.0 6.5 1 1 4 6 6 5 0 Autophagy protein 16 (ATG16) ApoC-I PF04691.12 OQS01907.1 - 1.8 8.6 8.8 3.4 7.7 0.2 4.6 4 0 0 4 4 4 0 Apolipoprotein C-I (ApoC-1) APG6 PF04111.12 OQS01908.1 - 1.6e-51 174.8 0.0 9.6e-51 172.3 0.0 2.3 2 0 0 2 2 2 1 Apg6 BARA domain APG6_N PF17675.1 OQS01908.1 - 5.6e-05 23.7 9.2 8.7e-05 23.1 9.2 1.2 1 0 0 1 1 1 1 Apg6 coiled-coil region Ank_2 PF12796.7 OQS01910.1 - 1.1e-19 70.7 4.5 2.1e-11 44.3 0.2 2.4 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQS01910.1 - 4e-13 49.6 0.1 1.5e-08 35.0 0.0 3.2 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 OQS01910.1 - 9.7e-13 47.9 3.0 0.0063 16.9 0.0 4.2 3 1 1 4 4 4 4 Ankyrin repeat Ank_3 PF13606.6 OQS01910.1 - 1.1e-09 37.7 0.1 0.00086 19.6 0.0 4.2 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.6 OQS01910.1 - 1.7e-08 34.6 0.8 0.002 18.4 0.0 3.7 2 1 2 4 4 4 2 Ankyrin repeats (many copies) BRCT_2 PF16589.5 OQS01912.1 - 2.2e-17 63.2 0.2 2.5e-11 43.9 0.0 3.1 3 0 0 3 3 3 2 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 OQS01912.1 - 2.3e-12 47.1 2.5 9.2e-07 29.2 0.0 3.5 3 1 0 3 3 3 2 BRCA1 C Terminus (BRCT) domain EF-hand_7 PF13499.6 OQS01912.1 - 2.8e-08 34.1 0.2 6.8e-08 32.9 0.1 1.7 2 0 0 2 2 1 1 EF-hand domain pair EF-hand_6 PF13405.6 OQS01912.1 - 1.9e-05 24.2 0.0 0.2 11.7 0.0 2.7 2 1 0 2 2 2 2 EF-hand domain RTT107_BRCT_5 PF16770.5 OQS01912.1 - 7.7e-05 22.5 0.0 0.0031 17.4 0.0 2.9 2 0 0 2 2 2 1 Regulator of Ty1 transposition protein 107 BRCT domain EF-hand_8 PF13833.6 OQS01912.1 - 0.00039 20.2 0.0 0.001 18.8 0.0 1.7 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 OQS01912.1 - 0.00042 19.7 0.0 0.46 10.2 0.0 2.7 2 0 0 2 2 2 2 EF hand zf-RanBP PF00641.18 OQS01912.1 - 0.00083 18.6 6.6 0.00083 18.6 6.6 2.2 2 0 0 2 2 2 1 Zn-finger in Ran binding protein and others RIIa PF02197.17 OQS01912.1 - 0.0069 16.0 0.0 0.019 14.6 0.0 1.7 1 0 0 1 1 1 1 Regulatory subunit of type II PKA R-subunit PTCB-BRCT PF12738.7 OQS01912.1 - 0.011 15.6 0.1 0.28 11.1 0.0 2.9 2 1 0 2 2 2 0 twin BRCT domain BRCT_3 PF18428.1 OQS01912.1 - 0.05 13.7 1.9 9.9 6.3 0.2 3.7 3 1 0 3 3 3 0 BRCA1 C Terminus (BRCT) domain Ank_2 PF12796.7 OQS01913.1 - 2.2e-16 60.2 0.1 9e-09 35.8 0.1 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 OQS01913.1 - 1.4e-12 47.5 1.8 0.0017 18.7 0.0 3.9 4 0 0 4 4 4 3 Ankyrin repeat Ank_3 PF13606.6 OQS01913.1 - 2e-10 39.9 0.3 0.12 13.0 0.0 3.8 4 0 0 4 4 4 3 Ankyrin repeat Ank_4 PF13637.6 OQS01913.1 - 1.5e-09 38.2 2.0 0.00023 21.7 0.1 2.7 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 OQS01913.1 - 5.3e-09 36.2 0.2 0.001 19.3 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) PTCB-BRCT PF12738.7 OQS01913.1 - 0.061 13.3 0.1 0.27 11.2 0.0 2.1 1 1 1 2 2 2 0 twin BRCT domain DHC_N1 PF08385.12 OQS01914.1 - 3.1e-182 607.1 4.0 3.1e-182 607.1 4.0 3.5 4 1 0 4 4 4 1 Dynein heavy chain, N-terminal region 1 AAA_6 PF12774.7 OQS01914.1 - 3.9e-138 459.9 0.1 2.9e-75 253.3 0.0 2.7 2 0 0 2 2 2 2 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 OQS01914.1 - 8.7e-101 337.9 3.4 8.7e-101 337.9 3.4 4.6 4 1 0 4 4 3 1 Dynein heavy chain, N-terminal region 2 AAA_8 PF12780.7 OQS01914.1 - 4.3e-87 291.7 0.0 7.1e-86 287.7 0.0 2.7 2 0 0 2 2 2 1 P-loop containing dynein motor region D4 Dynein_C PF18199.1 OQS01914.1 - 2.5e-76 256.9 0.1 2.5e-76 256.9 0.1 2.4 3 0 0 3 3 2 1 Dynein heavy chain C-terminal domain MT PF12777.7 OQS01914.1 - 5.9e-75 252.4 16.4 1.1e-74 251.5 16.4 1.5 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_9 PF12781.7 OQS01914.1 - 7.2e-74 247.6 8.5 3.4e-72 242.1 8.5 2.8 1 1 0 1 1 1 1 ATP-binding dynein motor region AAA_7 PF12775.7 OQS01914.1 - 5.6e-70 234.5 2.4 2e-62 209.9 0.0 4.3 5 0 0 5 5 3 3 P-loop containing dynein motor region AAA_lid_11 PF18198.1 OQS01914.1 - 6.3e-40 136.7 0.0 4.1e-39 134.0 0.0 2.4 2 0 0 2 2 2 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 OQS01914.1 - 7.4e-36 122.8 6.3 4.3e-34 117.1 0.0 4.1 5 0 0 5 5 2 1 Dynein heavy chain region D6 P-loop domain AAA_5 PF07728.14 OQS01914.1 - 1.1e-22 80.5 0.0 2e-10 40.8 0.0 5.4 4 1 0 4 4 4 3 AAA domain (dynein-related subfamily) AAA_lid_1 PF17857.1 OQS01914.1 - 2.6e-21 75.7 0.2 1.5e-20 73.3 0.2 2.5 1 0 0 1 1 1 1 AAA+ lid domain Dynein_AAA_lid PF17852.1 OQS01914.1 - 5.5e-12 45.9 0.1 2e-11 44.1 0.1 2.1 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA PF00004.29 OQS01914.1 - 7e-07 29.7 1.0 1 9.8 0.0 5.9 6 0 0 6 6 6 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 OQS01914.1 - 3.4e-06 27.5 0.0 0.85 10.0 0.0 5.6 4 0 0 4 4 4 2 AAA ATPase domain AAA_19 PF13245.6 OQS01914.1 - 6.5e-06 26.5 0.4 0.33 11.3 0.0 3.9 3 0 0 3 3 3 2 AAA domain AAA_18 PF13238.6 OQS01914.1 - 1.9e-05 25.2 0.0 0.56 10.8 0.0 4.0 4 0 0 4 4 2 2 AAA domain AAA_22 PF13401.6 OQS01914.1 - 2.6e-05 24.5 0.3 0.21 11.9 0.0 4.8 4 0 0 4 4 3 1 AAA domain TsaE PF02367.17 OQS01914.1 - 4.7e-05 23.4 0.3 0.22 11.6 0.0 4.5 4 0 0 4 4 4 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE SRP54 PF00448.22 OQS01914.1 - 5.3e-05 22.9 0.5 0.3 10.7 0.0 4.2 4 0 0 4 4 4 1 SRP54-type protein, GTPase domain ABC_tran PF00005.27 OQS01914.1 - 0.00035 21.1 0.1 1.2 9.6 0.0 3.6 3 0 0 3 3 2 1 ABC transporter AAA_28 PF13521.6 OQS01914.1 - 0.00069 19.9 0.0 5 7.4 0.0 4.2 3 0 0 3 3 3 0 AAA domain AAA_29 PF13555.6 OQS01914.1 - 0.0012 18.6 1.7 2.4 8.0 0.0 4.2 4 0 0 4 4 4 1 P-loop containing region of AAA domain RNA_helicase PF00910.22 OQS01914.1 - 0.0014 19.0 0.0 7.1 7.1 0.0 4.0 3 0 0 3 3 3 0 RNA helicase AAA_24 PF13479.6 OQS01914.1 - 0.0018 18.0 0.1 5.8 6.6 0.0 3.7 3 0 0 3 3 3 0 AAA domain AAA_30 PF13604.6 OQS01914.1 - 0.002 17.9 3.6 0.51 10.0 0.0 4.0 4 0 0 4 4 4 1 AAA domain RsgA_GTPase PF03193.16 OQS01914.1 - 0.002 18.0 0.2 0.86 9.5 0.0 3.2 3 0 0 3 3 2 1 RsgA GTPase AAA_14 PF13173.6 OQS01914.1 - 0.0033 17.5 0.0 1.1 9.3 0.0 3.4 2 0 0 2 2 2 1 AAA domain cobW PF02492.19 OQS01914.1 - 0.0065 16.1 0.0 1.6 8.3 0.0 2.8 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain Sigma54_activat PF00158.26 OQS01914.1 - 0.0079 15.9 0.0 3.5 7.3 0.0 3.4 3 0 0 3 3 3 1 Sigma-54 interaction domain Mg_chelatase PF01078.21 OQS01914.1 - 0.0091 15.4 0.9 0.045 13.1 0.0 2.6 3 0 0 3 3 2 1 Magnesium chelatase, subunit ChlI T2SSE PF00437.20 OQS01914.1 - 0.01 14.9 0.1 2.6 7.0 0.0 3.8 4 0 0 4 4 3 0 Type II/IV secretion system protein AAA_33 PF13671.6 OQS01914.1 - 0.014 15.6 2.1 3.7 7.7 0.0 4.3 4 0 0 4 4 3 0 AAA domain NACHT PF05729.12 OQS01914.1 - 0.017 15.1 0.7 0.36 10.7 0.0 3.2 3 0 0 3 3 2 0 NACHT domain Roc PF08477.13 OQS01914.1 - 0.018 15.2 0.4 6.8 6.9 0.0 3.4 3 0 0 3 3 2 0 Ras of Complex, Roc, domain of DAPkinase ATP_bind_1 PF03029.17 OQS01914.1 - 0.028 14.2 0.1 5 6.8 0.0 4.1 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein DUF948 PF06103.11 OQS01914.1 - 0.1 12.8 6.0 1.3 9.3 1.0 3.9 3 0 0 3 3 2 0 Bacterial protein of unknown function (DUF948) AAA_25 PF13481.6 OQS01914.1 - 0.12 11.9 0.7 14 5.2 0.0 3.4 3 0 0 3 3 3 0 AAA domain HNOBA PF07701.14 OQS01914.1 - 0.18 11.2 7.9 0.024 14.1 1.8 2.7 2 0 0 2 2 2 0 Heme NO binding associated PduV-EutP PF10662.9 OQS01914.1 - 0.24 11.2 1.3 11 5.7 0.0 3.2 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation DUF745 PF05335.13 OQS01914.1 - 0.7 9.6 21.3 4.2 7.1 9.1 3.2 2 0 0 2 2 2 0 Protein of unknown function (DUF745) AAA_23 PF13476.6 OQS01914.1 - 1.1 9.7 0.0 1.1 9.7 0.0 5.7 4 1 0 4 4 2 0 AAA domain Cytidylate_kin PF02224.18 OQS01914.1 - 1.7 8.4 7.9 1.7 8.3 0.0 3.5 4 0 0 4 4 3 0 Cytidylate kinase CENP-O PF09496.10 OQS01914.1 - 4.9 7.1 6.6 6.3 6.7 4.6 2.2 2 0 0 2 2 1 0 Cenp-O kinetochore centromere component YABBY PF04690.13 OQS01915.1 - 0.011 16.3 0.5 0.012 16.2 0.5 1.2 1 1 0 1 1 1 0 YABBY protein Ank_2 PF12796.7 OQS01916.1 - 1.3e-08 35.3 0.1 2e-08 34.7 0.1 1.3 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQS01916.1 - 1.6e-05 25.3 0.0 2.2e-05 24.9 0.0 1.2 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.30 OQS01916.1 - 0.00015 22.1 0.9 0.015 15.7 0.3 2.2 1 1 1 2 2 2 2 Ankyrin repeat Ank_3 PF13606.6 OQS01916.1 - 0.0026 18.1 0.0 1.5 9.6 0.0 2.4 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.6 OQS01916.1 - 0.014 15.7 0.2 0.046 14.1 0.1 1.8 1 1 1 2 2 2 0 Ankyrin repeats (many copies) Ank_2 PF12796.7 OQS01917.1 - 3.6e-08 33.9 0.0 4.4e-08 33.6 0.0 1.1 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 OQS01917.1 - 2.8e-06 27.5 0.0 0.0013 19.1 0.0 2.1 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.6 OQS01917.1 - 1.5e-05 25.4 0.0 2.7e-05 24.6 0.0 1.4 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQS01917.1 - 0.00083 19.6 0.0 0.079 13.6 0.0 2.1 2 0 0 2 2 2 1 Ankyrin repeat Ank_5 PF13857.6 OQS01917.1 - 0.0071 16.6 0.0 0.64 10.4 0.0 1.8 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Arg_repressor PF01316.21 OQS01917.1 - 0.11 12.2 0.0 1.7 8.5 0.0 2.0 2 0 0 2 2 2 0 Arginine repressor, DNA binding domain PTCB-BRCT PF12738.7 OQS01917.1 - 0.12 12.4 0.1 0.21 11.6 0.1 1.5 1 1 0 1 1 1 0 twin BRCT domain WD40 PF00400.32 OQS01918.1 - 1.9e-19 69.7 11.7 6e-08 33.2 0.0 5.8 6 2 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OQS01918.1 - 8e-05 22.9 0.6 0.035 14.4 0.0 3.3 2 1 1 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 OQS01918.1 - 0.094 11.7 0.0 1.1 8.2 0.0 2.5 3 1 1 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein BT1 PF03092.16 OQS01919.1 - 2.3e-12 46.0 15.3 6.3e-12 44.5 0.8 4.0 3 1 1 4 4 4 3 BT1 family PUCC PF03209.15 OQS01919.1 - 7.8e-05 21.9 0.3 7.8e-05 21.9 0.3 2.7 3 0 0 3 3 3 1 PUCC protein Dicer_N PF17895.1 OQS01919.1 - 0.028 14.3 0.0 0.056 13.3 0.0 1.4 1 0 0 1 1 1 0 Giardia Dicer N-terminal domain DUF2085 PF09858.9 OQS01919.1 - 0.57 10.7 16.5 0.25 11.8 1.6 4.3 4 1 1 5 5 5 0 Predicted membrane protein (DUF2085) BT1 PF03092.16 OQS01920.1 - 5.6e-10 38.1 4.5 2e-08 33.0 2.2 2.0 2 0 0 2 2 2 2 BT1 family PUCC PF03209.15 OQS01920.1 - 0.00035 19.7 0.3 0.00035 19.7 0.3 2.3 3 0 0 3 3 3 2 PUCC protein BT1 PF03092.16 OQS01921.1 - 4.7e-10 38.3 11.9 9e-10 37.4 0.6 3.0 3 0 0 3 3 3 3 BT1 family HEAT_2 PF13646.6 OQS01922.1 - 1.8e-14 53.9 14.2 0.021 15.2 0.0 9.5 6 3 4 11 11 11 5 HEAT repeats HEAT_EZ PF13513.6 OQS01922.1 - 2.9e-12 46.8 18.8 0.00019 21.8 0.0 10.6 9 3 4 13 13 13 4 HEAT-like repeat HEAT PF02985.22 OQS01922.1 - 4.6e-11 42.0 25.6 0.00013 21.9 0.0 14.0 17 0 0 17 17 17 1 HEAT repeat IBN_N PF03810.19 OQS01922.1 - 8e-09 35.3 3.7 4.2e-06 26.6 0.0 3.7 4 0 0 4 4 4 2 Importin-beta N-terminal domain CLASP_N PF12348.8 OQS01922.1 - 4.7e-07 29.6 3.4 0.047 13.3 0.2 6.2 6 2 2 8 8 8 1 CLASP N terminal Cnd1 PF12717.7 OQS01922.1 - 3.2e-05 24.0 8.0 3.3 7.7 1.0 5.8 4 2 2 6 6 6 2 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 OQS01922.1 - 4.7e-05 23.9 4.3 0.51 11.0 0.0 5.9 7 1 1 8 8 8 2 Vacuolar 14 Fab1-binding region Tti2 PF10521.9 OQS01922.1 - 4.9e-05 23.0 0.2 0.0006 19.4 0.0 3.0 2 1 0 2 2 2 1 Tti2 family Arm PF00514.23 OQS01922.1 - 0.00032 20.6 6.4 1.3 9.2 0.0 6.5 6 0 0 6 6 6 1 Armadillo/beta-catenin-like repeat Importin_rep_4 PF18808.1 OQS01922.1 - 0.00079 19.7 1.9 2.8 8.3 0.0 4.2 4 0 0 4 4 4 2 Importin repeat RICTOR_V PF14668.6 OQS01922.1 - 0.0099 16.1 0.5 21 5.4 0.0 4.3 2 1 1 3 3 3 0 Rapamycin-insensitive companion of mTOR, domain 5 Nipped-B_C PF12830.7 OQS01922.1 - 0.022 14.7 2.0 0.045 13.7 0.3 2.3 2 0 0 2 2 2 0 Sister chromatid cohesion C-terminus COG4 PF08318.12 OQS01922.1 - 0.15 11.1 0.1 0.35 9.9 0.1 1.6 1 0 0 1 1 1 0 COG4 transport protein RTP1_C1 PF10363.9 OQS01922.1 - 2.1 8.5 7.5 25 5.1 0.1 5.4 6 0 0 6 6 6 0 Required for nuclear transport of RNA pol II C-terminus 1 Lip_A_acyltrans PF03279.13 OQS01923.1 - 9.5e-08 31.5 0.0 1.1e-07 31.3 0.0 1.0 1 0 0 1 1 1 1 Bacterial lipid A biosynthesis acyltransferase SPT16 PF08644.11 OQS01925.1 - 1.8e-55 187.3 0.1 1.8e-55 187.3 0.1 2.7 2 0 0 2 2 2 1 FACT complex subunit (SPT16/CDC68) FACT-Spt16_Nlob PF14826.6 OQS01925.1 - 8.8e-43 145.9 0.3 3.1e-42 144.1 0.0 2.2 2 0 0 2 2 2 1 FACT complex subunit SPT16 N-terminal lobe domain Peptidase_M24 PF00557.24 OQS01925.1 - 5.9e-25 88.2 0.0 1.1e-24 87.3 0.0 1.5 1 0 0 1 1 1 1 Metallopeptidase family M24 Rtt106 PF08512.12 OQS01925.1 - 3.5e-14 53.0 0.9 9.9e-14 51.5 0.9 1.8 1 0 0 1 1 1 1 Histone chaperone Rttp106-like Nop14 PF04147.12 OQS01925.1 - 1.4 7.1 40.3 1.1 7.4 28.8 2.5 2 0 0 2 2 2 0 Nop14-like family CDC45 PF02724.14 OQS01925.1 - 4.5 5.5 42.7 0.18 10.1 6.5 2.5 2 0 0 2 2 2 0 CDC45-like protein Thioredoxin PF00085.20 OQS01926.1 - 2.4e-62 207.3 0.0 9.7e-31 105.8 0.1 2.3 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_2 PF13098.6 OQS01926.1 - 1.7e-09 38.1 0.6 0.00076 19.9 0.1 3.9 2 2 0 2 2 2 2 Thioredoxin-like domain OST3_OST6 PF04756.13 OQS01926.1 - 8.9e-07 28.5 0.0 0.013 14.9 0.0 2.4 2 0 0 2 2 2 2 OST3 / OST6 family, transporter family Thioredoxin_6 PF13848.6 OQS01926.1 - 1.9e-06 27.9 0.0 0.079 12.9 0.0 3.0 2 1 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_3 PF13192.6 OQS01926.1 - 2.2e-06 27.6 0.0 0.046 13.8 0.0 2.4 2 0 0 2 2 2 2 Thioredoxin domain Thioredoxin_8 PF13905.6 OQS01926.1 - 7.3e-06 26.2 0.0 1 9.7 0.0 4.1 2 2 2 4 4 4 2 Thioredoxin-like AhpC-TSA PF00578.21 OQS01926.1 - 1.5e-05 24.9 0.0 0.03 14.2 0.0 2.5 2 0 0 2 2 2 2 AhpC/TSA family Thioredoxin_7 PF13899.6 OQS01926.1 - 6.9e-05 23.0 0.0 0.22 11.7 0.0 2.6 2 0 0 2 2 2 2 Thioredoxin-like Thioredoxin_9 PF14595.6 OQS01926.1 - 0.004 16.9 0.0 0.19 11.5 0.0 2.3 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_4 PF13462.6 OQS01926.1 - 0.004 17.3 1.0 35 4.5 0.0 4.2 3 2 2 5 5 5 0 Thioredoxin GBS_Bsp-like PF08481.10 OQS01926.1 - 0.12 12.5 0.1 0.31 11.2 0.0 1.7 2 0 0 2 2 2 0 GBS Bsp-like repeat MFS_2 PF13347.6 OQS01927.1 - 1.5e-10 40.2 9.5 1.5e-10 40.2 9.5 2.8 2 1 1 3 3 3 2 MFS/sugar transport protein TMEM126 PF07114.11 OQS01927.1 - 0.031 13.7 0.6 0.031 13.7 0.6 1.9 2 0 0 2 2 2 0 Transmembrane protein 126 BAR PF03114.18 OQS01928.1 - 4.4e-06 26.5 2.0 9.1e-06 25.5 2.0 1.5 1 0 0 1 1 1 1 BAR domain Vps5 PF09325.10 OQS01928.1 - 0.0029 17.2 2.8 0.006 16.2 2.8 1.7 1 1 0 1 1 1 1 Vps5 C terminal like Fib_alpha PF08702.10 OQS01928.1 - 0.045 13.9 1.5 0.098 12.8 1.5 1.6 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family P4Ha_N PF08336.11 OQS01928.1 - 0.068 13.2 1.0 0.8 9.7 0.1 2.8 2 1 0 2 2 2 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region BAR_3 PF16746.5 OQS01928.1 - 0.12 12.1 2.9 0.27 10.9 2.9 1.6 1 1 0 1 1 1 0 BAR domain of APPL family Tctex-1 PF03645.13 OQS01929.1 - 1.6e-26 92.5 0.7 3.3e-26 91.5 0.7 1.5 1 0 0 1 1 1 1 Tctex-1 family CRAL_TRIO PF00650.20 OQS01929.1 - 2.2e-18 66.5 0.0 3.4e-18 65.9 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain Beach PF02138.18 OQS01931.1 - 6.8e-32 110.9 0.0 1.2e-31 110.1 0.0 1.4 1 0 0 1 1 1 1 Beige/BEACH domain WD40 PF00400.32 OQS01931.1 - 0.0018 19.0 2.5 0.11 13.4 0.3 3.0 2 0 0 2 2 2 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OQS01931.1 - 0.11 12.8 0.1 2.4 8.5 0.0 2.5 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain HEAT PF02985.22 OQS01931.1 - 0.14 12.5 0.3 1.8 9.0 0.0 3.2 2 0 0 2 2 2 0 HEAT repeat Cu-oxidase_3 PF07732.15 OQS01932.1 - 2.7e-16 59.7 0.1 2.7e-16 59.7 0.1 3.6 4 0 0 4 4 4 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 OQS01932.1 - 1.6e-11 44.1 5.1 1.6e-11 44.1 5.1 3.5 3 1 0 3 3 3 1 Multicopper oxidase NAD_Gly3P_dh_C PF07479.14 OQS01933.1 - 2.2e-46 157.7 0.0 5.6e-46 156.3 0.0 1.8 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus NAD_Gly3P_dh_N PF01210.23 OQS01933.1 - 1.4e-42 145.3 0.0 4.5e-42 143.7 0.0 1.8 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Beta_elim_lyase PF01212.21 OQS01933.1 - 1.8e-28 99.7 0.0 3.3e-28 98.8 0.0 1.4 1 0 0 1 1 1 1 Beta-eliminating lyase TIR_2 PF13676.6 OQS01933.1 - 6.3e-05 23.6 0.1 0.00021 21.9 0.1 1.9 1 0 0 1 1 1 1 TIR domain Arm PF00514.23 OQS01933.1 - 0.022 14.8 0.1 72 3.6 0.0 5.1 6 0 0 6 6 6 0 Armadillo/beta-catenin-like repeat DKCLD PF08068.12 OQS01934.1 - 2.5e-33 113.9 1.1 2.2e-31 107.7 0.4 3.0 3 0 0 3 3 3 1 DKCLD (NUC011) domain TruB_N PF01509.18 OQS01934.1 - 2.4e-24 86.4 0.9 2e-21 76.9 0.9 3.4 1 1 0 1 1 1 1 TruB family pseudouridylate synthase (N terminal domain) TruB_C_2 PF16198.5 OQS01934.1 - 8.5e-22 77.1 1.0 1.7e-21 76.1 1.0 1.5 1 0 0 1 1 1 1 tRNA pseudouridylate synthase B C-terminal domain PUA PF01472.20 OQS01934.1 - 4e-20 71.6 2.4 8.2e-20 70.6 2.4 1.6 1 0 0 1 1 1 1 PUA domain Coilin_N PF15862.5 OQS01934.1 - 0.0032 17.3 6.0 0.0032 17.3 6.0 1.6 2 0 0 2 2 2 1 Coilin N-terminus UPF0113 PF03657.13 OQS01934.1 - 0.0041 17.4 0.0 0.012 15.8 0.0 1.8 1 0 0 1 1 1 1 UPF0113 PUA domain RR_TM4-6 PF06459.12 OQS01934.1 - 0.02 14.7 14.4 0.028 14.2 14.4 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 GAGA_bind PF06217.12 OQS01934.1 - 0.22 11.8 8.3 0.32 11.2 8.3 1.3 1 0 0 1 1 1 0 GAGA binding protein-like family SKN1 PF03935.15 OQS01935.1 - 2.3e-64 217.7 21.0 3.2e-42 144.6 13.2 4.5 2 2 0 2 2 2 2 Beta-glucan synthesis-associated protein (SKN1) Ribosomal_S18 PF01084.20 OQS01936.1 - 1.6e-16 60.3 0.2 2.7e-16 59.5 0.2 1.4 1 0 0 1 1 1 1 Ribosomal protein S18 COX16 PF14138.6 OQS01936.1 - 0.13 12.8 0.4 0.41 11.2 0.4 1.8 1 0 0 1 1 1 0 Cytochrome c oxidase assembly protein COX16 SET PF00856.28 OQS01938.1 - 6.5e-15 55.9 0.0 1.2e-14 55.1 0.0 1.4 1 0 0 1 1 1 1 SET domain Rubis-subs-bind PF09273.11 OQS01938.1 - 6.6e-11 43.0 0.9 1.1e-10 42.3 0.3 1.7 2 0 0 2 2 2 1 Rubisco LSMT substrate-binding YpsA PF06908.11 OQS01938.1 - 0.11 12.5 0.1 0.19 11.7 0.1 1.4 1 0 0 1 1 1 0 YspA SLOG family Ank_2 PF12796.7 OQS01939.1 - 2.9e-21 75.8 4.2 1.5e-08 35.1 0.1 4.6 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQS01939.1 - 6.4e-16 58.5 10.6 0.0029 18.1 0.0 6.0 4 2 2 6 6 6 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 OQS01939.1 - 8.4e-14 51.5 11.9 0.049 14.0 0.0 8.9 1 1 8 9 9 9 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQS01939.1 - 5.8e-10 38.5 6.6 9.8 7.1 0.0 8.7 9 0 0 9 9 9 2 Ankyrin repeat DUF5049 PF16468.5 OQS01939.1 - 0.021 14.7 0.2 15 5.6 0.0 4.2 2 2 3 5 5 5 0 Domain of unknown function (DUF5049) Ank PF00023.30 OQS01939.1 - 0.16 12.5 2.6 2.1e+02 2.6 0.1 5.3 5 1 1 6 6 6 0 Ankyrin repeat XPA_N PF01286.18 OQS01939.1 - 6.3 6.9 6.5 0.24 11.5 0.5 1.8 2 0 0 2 2 2 0 XPA protein N-terminal FPN1 PF06963.12 OQS01940.1 - 1.5e-68 231.4 24.4 2.6e-36 125.1 5.6 2.2 1 1 1 2 2 2 2 Ferroportin1 (FPN1) Ank_2 PF12796.7 OQS01940.1 - 2.8e-24 85.5 2.2 5.2e-11 43.0 0.4 2.9 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQS01940.1 - 1.7e-20 73.1 9.1 6.1e-09 36.3 0.0 4.6 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 OQS01940.1 - 1.4e-14 53.9 1.3 8.6e-08 32.3 0.1 4.0 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 OQS01940.1 - 6.5e-14 51.7 8.7 0.0057 17.1 0.0 6.6 7 0 0 7 7 7 3 Ankyrin repeat Ank_3 PF13606.6 OQS01940.1 - 9.3e-14 50.2 1.5 0.0029 18.0 0.0 5.3 5 0 0 5 5 5 3 Ankyrin repeat DBD_Tnp_Mut PF03108.15 OQS01940.1 - 0.33 11.0 2.2 0.74 9.8 2.2 1.5 1 0 0 1 1 1 0 MuDR family transposase DDE_1 PF03184.19 OQS01941.1 - 1.9e-31 109.0 0.0 3.7e-31 108.1 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.16 OQS01941.1 - 5.2e-11 42.4 0.1 1.7e-10 40.8 0.0 1.9 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain HTH_24 PF13412.6 OQS01941.1 - 0.00018 21.0 0.1 0.0004 19.9 0.1 1.6 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_AsnC-type PF13404.6 OQS01941.1 - 0.021 14.7 0.0 0.066 13.1 0.0 1.9 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain Acetyltransf_1 PF00583.25 OQS01942.1 - 3.6e-09 36.9 0.0 5.3e-09 36.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 OQS01942.1 - 7.5e-08 32.4 0.0 1.1e-07 31.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 OQS01942.1 - 4.4e-06 27.0 0.0 7.8e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain UPF0175 PF03683.13 OQS01942.1 - 0.12 12.1 0.0 0.23 11.2 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0175) Gpi16 PF04113.14 OQS01943.1 - 1.3e-105 354.0 1.3 2.5e-64 217.7 0.0 2.9 1 1 1 2 2 2 2 Gpi16 subunit, GPI transamidase component CENP-R PF06729.12 OQS01943.1 - 0.12 12.3 0.2 0.21 11.5 0.2 1.3 1 0 0 1 1 1 0 Kinetochore component, CENP-R tRNA_int_end_N2 PF12928.7 OQS01944.1 - 4.7e-06 26.7 0.0 7.9e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 tRNA-splicing endonuclease subunit sen54 N-term tRNA_int_endo_N PF02778.14 OQS01944.1 - 0.066 12.9 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 tRNA intron endonuclease, N-terminal domain GPI2 PF06432.11 OQS01945.1 - 1.1e-80 271.0 18.0 1.3e-80 270.9 18.0 1.0 1 0 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase PspB PF06667.12 OQS01945.1 - 2 8.5 4.3 0.65 10.1 0.7 2.1 2 0 0 2 2 2 0 Phage shock protein B Peptidase_S51 PF03575.17 OQS01946.1 - 7.4e-36 123.7 0.0 1.3e-35 122.9 0.0 1.3 1 1 0 1 1 1 1 Peptidase family S51 zf-BED PF02892.15 OQS01946.1 - 0.1 12.6 2.3 0.2 11.7 2.3 1.5 1 0 0 1 1 1 0 BED zinc finger Myb_DNA-binding PF00249.31 OQS01947.1 - 4.7e-09 36.3 0.1 7.8e-09 35.6 0.1 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OQS01947.1 - 0.14 12.4 0.1 0.3 11.4 0.1 1.6 1 0 0 1 1 1 0 Myb-like DNA-binding domain CBFB_NFYA PF02045.15 OQS01948.1 - 2.6e-25 88.8 7.9 2.6e-25 88.8 7.9 2.0 2 0 0 2 2 2 1 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B DUF3117 PF11314.8 OQS01948.1 - 0.028 14.2 0.1 3.6 7.5 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3117) DivIC PF04977.15 OQS01948.1 - 0.085 12.6 0.2 0.085 12.6 0.2 3.0 3 0 0 3 3 3 0 Septum formation initiator Mito_carr PF00153.27 OQS01949.1 - 6.3e-59 195.9 6.4 1.3e-20 73.0 0.4 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein WD40 PF00400.32 OQS01950.1 - 5.8e-44 147.2 19.3 8.1e-09 36.0 0.7 7.6 7 0 0 7 7 7 7 WD domain, G-beta repeat RNase_PH PF01138.21 OQS01950.1 - 3.7e-27 95.4 0.2 1.1e-26 93.9 0.0 1.9 2 0 0 2 2 2 1 3' exoribonuclease family, domain 1 ANAPC4_WD40 PF12894.7 OQS01950.1 - 6.6e-16 58.4 3.1 9.2e-06 25.9 0.1 5.6 3 1 4 7 7 7 5 Anaphase-promoting complex subunit 4 WD40 domain PRP4 PF08799.11 OQS01950.1 - 4.6e-12 45.3 0.4 4.6e-12 45.3 0.4 2.2 3 0 0 3 3 3 1 pre-mRNA processing factor 4 (PRP4) like eIF2A PF08662.11 OQS01950.1 - 5.2e-07 29.7 0.0 0.00021 21.2 0.1 3.2 1 1 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 OQS01950.1 - 4.5e-06 25.8 0.1 0.00075 18.6 0.1 3.4 2 2 1 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein RNase_PH_C PF03725.15 OQS01950.1 - 0.00016 21.7 0.2 0.00056 19.9 0.1 2.0 2 0 0 2 2 2 1 3' exoribonuclease family, domain 2 WD40_like PF17005.5 OQS01950.1 - 0.03 13.7 0.0 0.29 10.4 0.0 2.5 2 0 0 2 2 2 0 WD40-like domain ImcF-related_N PF14331.6 OQS01950.1 - 0.34 10.2 4.2 0.56 9.5 4.2 1.2 1 0 0 1 1 1 0 ImcF-related N-terminal domain Nup160 PF11715.8 OQS01950.1 - 3.3 6.2 7.3 1.5 7.4 0.2 3.2 2 1 1 4 4 4 0 Nucleoporin Nup120/160 Med12-LCEWAV PF12145.8 OQS01952.1 - 0.0011 17.9 0.0 0.0019 17.1 0.0 1.3 1 0 0 1 1 1 1 Eukaryotic Mediator 12 subunit domain MCD PF05292.11 OQS01953.1 - 7.3e-66 222.4 0.0 1e-65 221.9 0.0 1.2 1 0 0 1 1 1 1 Malonyl-CoA decarboxylase C-terminal domain cNMP_binding PF00027.29 OQS01953.1 - 1.1e-11 44.6 0.0 1.9e-11 43.8 0.0 1.4 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain TPR_1 PF00515.28 OQS01954.1 - 2.9e-60 197.8 29.3 2.7e-05 23.8 0.1 22.8 25 0 0 25 25 24 12 Tetratricopeptide repeat TPR_2 PF07719.17 OQS01954.1 - 3.2e-54 176.7 33.7 0.00033 20.5 0.1 22.2 24 2 1 25 25 23 12 Tetratricopeptide repeat TPR_11 PF13414.6 OQS01954.1 - 7.5e-49 163.2 15.4 4.5e-05 23.0 1.1 16.2 15 2 3 18 18 17 12 TPR repeat TPR_16 PF13432.6 OQS01954.1 - 1.8e-43 146.9 25.0 6.6e-06 26.7 0.0 12.4 10 2 2 13 13 13 8 Tetratricopeptide repeat TPR_9 PF13371.6 OQS01954.1 - 5.2e-33 113.0 36.5 3e-06 27.3 1.7 14.6 11 3 4 15 15 15 8 Tetratricopeptide repeat TPR_8 PF13181.6 OQS01954.1 - 1.5e-32 109.1 23.0 0.0042 17.2 0.1 17.8 19 0 0 19 19 17 5 Tetratricopeptide repeat TPR_17 PF13431.6 OQS01954.1 - 4e-30 102.0 31.4 0.0036 17.6 0.1 18.3 21 0 0 21 21 19 6 Tetratricopeptide repeat TPR_14 PF13428.6 OQS01954.1 - 3.8e-28 95.8 26.6 0.02 15.7 0.0 15.7 12 5 6 18 18 14 9 Tetratricopeptide repeat TPR_19 PF14559.6 OQS01954.1 - 2.2e-21 76.1 29.0 1.5e-06 28.6 0.1 10.7 10 3 3 13 13 12 5 Tetratricopeptide repeat TPR_7 PF13176.6 OQS01954.1 - 1.9e-15 55.7 21.7 0.032 14.3 0.0 13.5 14 0 0 14 14 14 3 Tetratricopeptide repeat TPR_12 PF13424.6 OQS01954.1 - 2.2e-15 56.7 47.6 0.017 15.4 0.1 14.0 12 4 4 17 17 15 5 Tetratricopeptide repeat TPR_6 PF13174.6 OQS01954.1 - 1.4e-10 41.1 33.5 0.23 12.2 0.0 14.1 17 0 0 17 17 15 3 Tetratricopeptide repeat NARP1 PF12569.8 OQS01954.1 - 6.9e-10 38.4 1.5 0.00014 20.9 0.0 5.6 5 1 1 6 6 6 2 NMDA receptor-regulated protein 1 TPR_20 PF14561.6 OQS01954.1 - 8.1e-07 29.3 7.3 2.8 8.3 0.1 7.2 7 2 2 9 9 8 2 Tetratricopeptide repeat ANAPC3 PF12895.7 OQS01954.1 - 4.4e-06 26.8 22.9 0.38 11.0 0.9 8.3 7 2 2 9 9 8 3 Anaphase-promoting complex, cyclosome, subunit 3 BTAD PF03704.17 OQS01954.1 - 0.00028 21.3 12.7 0.17 12.3 0.7 6.1 4 2 2 6 6 6 1 Bacterial transcriptional activator domain TPR_10 PF13374.6 OQS01954.1 - 0.0046 16.8 22.9 3.2 7.7 0.1 10.4 12 1 2 14 14 12 2 Tetratricopeptide repeat SHNi-TPR PF10516.9 OQS01954.1 - 0.011 15.1 4.9 15 5.1 0.0 7.2 9 0 0 9 9 9 0 SHNi-TPR TRAPPC-Trs85 PF12739.7 OQS01954.1 - 0.012 14.6 0.1 0.027 13.4 0.1 1.5 1 0 0 1 1 1 0 ER-Golgi trafficking TRAPP I complex 85 kDa subunit Coatomer_E PF04733.14 OQS01954.1 - 0.073 12.5 0.7 64 2.8 0.0 3.8 3 0 0 3 3 3 0 Coatomer epsilon subunit Baculo_PEP_C PF04513.12 OQS01955.1 - 0.039 14.0 0.4 0.039 14.0 0.4 1.0 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus LRR_4 PF12799.7 OQS01956.1 - 2.4e-26 91.3 37.8 2.5e-06 27.7 0.9 7.2 3 2 2 7 7 7 6 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 OQS01956.1 - 4.8e-18 64.7 33.5 9.3e-08 31.7 5.3 5.7 2 2 2 5 5 5 5 Leucine rich repeat LRR_9 PF14580.6 OQS01956.1 - 6.2e-16 58.4 14.6 1e-08 34.9 0.4 3.2 2 1 1 3 3 3 3 Leucine-rich repeat LRR_6 PF13516.6 OQS01956.1 - 4.4e-08 32.5 16.7 0.024 14.7 0.4 8.6 9 0 0 9 9 9 2 Leucine Rich repeat LRR_1 PF00560.33 OQS01956.1 - 0.42 11.3 26.8 7.2 7.6 0.0 8.7 9 0 0 9 9 9 0 Leucine Rich Repeat RRM_1 PF00076.22 OQS01958.1 - 5.6e-40 135.0 0.3 3.9e-19 68.2 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 OQS01958.1 - 5.7e-06 26.4 0.1 0.00038 20.5 0.0 2.3 2 0 0 2 2 2 1 RNA recognition motif OB_RNB PF08206.11 OQS01958.1 - 0.0021 17.7 0.1 0.6 9.8 0.0 2.4 2 0 0 2 2 2 2 Ribonuclease B OB domain PHM7_cyt PF14703.6 OQS01958.1 - 0.018 15.3 0.1 0.32 11.2 0.0 2.2 2 0 0 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter SET_assoc PF11767.8 OQS01958.1 - 0.019 14.6 0.6 0.049 13.3 0.1 1.9 2 0 0 2 2 2 0 Histone lysine methyltransferase SET associated Cas_Cas2CT1978 PF09707.10 OQS01958.1 - 0.073 13.1 0.0 4.6 7.4 0.0 2.3 2 0 0 2 2 2 0 CRISPR-associated protein (Cas_Cas2CT1978) APCDDC PF14921.6 OQS01958.1 - 0.16 11.4 0.0 0.22 10.9 0.0 1.2 1 0 0 1 1 1 0 Adenomatosis polyposis coli down-regulated 1 Rap_GAP PF02145.15 OQS01960.1 - 5.8e-37 127.0 0.0 1.8e-36 125.4 0.0 1.8 2 0 0 2 2 2 1 Rap/ran-GAP DUF3384 PF11864.8 OQS01960.1 - 5.4e-27 94.8 0.0 9.4e-25 87.4 0.0 2.5 1 1 0 1 1 1 1 Domain of unknown function (DUF3384) Met_10 PF02475.16 OQS01960.1 - 1.1e-26 93.9 0.0 2.9e-26 92.4 0.0 1.7 1 0 0 1 1 1 1 Met-10+ like-protein Kelch_4 PF13418.6 OQS01960.1 - 6.5e-24 83.7 0.2 2.4e-06 27.5 0.0 4.7 4 0 0 4 4 4 4 Galactose oxidase, central domain Kelch_5 PF13854.6 OQS01960.1 - 1.2e-16 60.3 0.4 3.8e-07 29.9 0.0 4.8 5 0 0 5 5 5 3 Kelch motif Kelch_1 PF01344.25 OQS01960.1 - 4.3e-16 58.2 0.0 9.1e-06 25.2 0.1 4.5 4 0 0 4 4 4 3 Kelch motif Kelch_6 PF13964.6 OQS01960.1 - 3.9e-14 52.3 3.6 0.00098 19.3 0.2 4.8 1 1 3 4 4 4 3 Kelch motif Kelch_2 PF07646.15 OQS01960.1 - 2.2e-10 40.1 3.1 0.0091 15.9 0.2 4.8 5 0 0 5 5 5 3 Kelch motif Kelch_3 PF13415.6 OQS01960.1 - 2.3e-09 37.3 0.2 0.025 14.9 0.0 4.7 4 0 0 4 4 4 2 Galactose oxidase, central domain Tuberin PF03542.16 OQS01960.1 - 0.00012 21.3 2.8 0.0027 16.9 0.2 3.2 2 1 0 2 2 2 1 Tuberin MTS PF05175.14 OQS01960.1 - 0.0097 15.5 0.0 0.023 14.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase small domain SPT16 PF08644.11 OQS01960.1 - 0.018 15.2 0.1 0.79 9.9 0.0 2.7 2 0 0 2 2 2 0 FACT complex subunit (SPT16/CDC68) Methyltransf_15 PF09445.10 OQS01960.1 - 0.06 12.9 0.1 0.39 10.3 0.0 2.5 4 0 0 4 4 4 0 RNA cap guanine-N2 methyltransferase CHAD PF05235.14 OQS01960.1 - 0.073 13.0 0.0 0.15 12.0 0.0 1.5 1 0 0 1 1 1 0 CHAD domain C2 PF00168.30 OQS01961.1 - 2.2e-45 153.2 2.1 1.4e-15 57.4 0.1 5.2 5 0 0 5 5 5 4 C2 domain PH PF00169.29 OQS01961.1 - 1.2e-13 51.4 0.0 3.2e-13 50.1 0.0 1.8 1 0 0 1 1 1 1 PH domain PH_8 PF15409.6 OQS01961.1 - 0.0028 17.9 0.0 0.0074 16.5 0.0 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain PH_11 PF15413.6 OQS01961.1 - 0.0081 16.6 0.1 0.12 12.9 0.1 2.7 1 1 0 1 1 1 1 Pleckstrin homology domain Peptidase_C69 PF03577.15 OQS01962.1 - 8.5e-43 146.8 0.2 1.1e-41 143.1 0.2 2.4 1 1 0 1 1 1 1 Peptidase family C69 Ank_2 PF12796.7 OQS01964.1 - 4.2e-22 78.5 1.6 2.5e-05 24.8 0.1 4.9 2 1 3 5 5 5 4 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OQS01964.1 - 1.2e-15 57.4 3.8 0.0013 19.0 0.1 8.0 3 1 6 9 9 9 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQS01964.1 - 1.2e-15 56.1 1.8 0.66 10.7 0.0 9.5 9 1 1 10 10 10 3 Ankyrin repeat Ank_4 PF13637.6 OQS01964.1 - 3.9e-14 52.8 4.6 0.0033 17.9 0.2 7.4 4 2 5 9 9 9 5 Ankyrin repeats (many copies) Ank PF00023.30 OQS01964.1 - 0.0008 19.8 0.3 5.2 7.7 0.0 4.9 3 2 1 4 4 4 1 Ankyrin repeat ScdA_N PF04405.14 OQS01964.1 - 0.27 10.9 2.2 0.81 9.4 0.1 2.5 3 0 0 3 3 3 0 Domain of Unknown function (DUF542) V_ATPase_I PF01496.19 OQS01965.1 - 5.2e-131 438.2 1.3 6.3e-131 437.9 1.3 1.1 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family DUF4261 PF14080.6 OQS01965.1 - 0.034 14.3 0.0 15 5.8 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4261) Pkinase_Tyr PF07714.17 OQS01966.1 - 1.7e-16 60.3 0.0 1.8e-16 60.2 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OQS01966.1 - 4.5e-16 59.0 0.0 5.1e-16 58.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain GpcrRhopsn4 PF10192.9 OQS01967.1 - 1.1e-45 156.1 18.8 1.4e-45 155.7 18.8 1.0 1 0 0 1 1 1 1 Rhodopsin-like GPCR transmembrane domain Lung_7-TM_R PF06814.13 OQS01967.1 - 8.9e-05 21.9 15.2 0.00013 21.3 15.2 1.2 1 0 0 1 1 1 1 Lung seven transmembrane receptor LapA_dom PF06305.11 OQS01967.1 - 0.16 11.8 0.0 0.16 11.8 0.0 3.0 4 0 0 4 4 4 0 Lipopolysaccharide assembly protein A domain Pkinase_Tyr PF07714.17 OQS01968.1 - 2.4e-26 92.6 0.9 3.5e-26 92.0 0.9 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OQS01968.1 - 2.3e-23 82.9 0.7 3.3e-23 82.4 0.7 1.2 1 0 0 1 1 1 1 Protein kinase domain RIO1 PF01163.22 OQS01968.1 - 0.11 12.1 0.6 0.18 11.4 0.6 1.3 1 0 0 1 1 1 0 RIO1 family APH PF01636.23 OQS01968.1 - 0.25 11.2 0.0 0.36 10.7 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family Ferric_reduct PF01794.19 OQS01969.1 - 4.4e-12 46.2 13.8 4.4e-12 46.2 13.8 2.2 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 OQS01969.1 - 1.3e-10 41.7 0.0 2.2e-07 31.1 0.0 2.3 1 1 0 1 1 1 1 Ferric reductase NAD binding domain DOMON PF03351.17 OQS01969.1 - 9.2e-08 32.3 0.0 9.9e-05 22.5 0.0 2.4 2 0 0 2 2 2 2 DOMON domain FAD_binding_8 PF08022.12 OQS01969.1 - 2.9e-07 30.6 0.1 9.7e-07 28.9 0.1 2.0 1 1 0 1 1 1 1 FAD-binding domain NAD_binding_1 PF00175.21 OQS01969.1 - 9.7e-05 23.0 0.0 0.00034 21.2 0.0 2.0 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain DUF4405 PF14358.6 OQS01969.1 - 0.0045 17.5 2.6 0.0045 17.5 2.6 3.9 5 0 0 5 5 5 1 Domain of unknown function (DUF4405) FAD_binding_6 PF00970.24 OQS01969.1 - 0.093 13.1 0.0 0.21 11.9 0.0 1.6 1 0 0 1 1 1 0 Oxidoreductase FAD-binding domain Pkinase_Tyr PF07714.17 OQS01970.1 - 2.2e-50 171.3 0.0 3.6e-50 170.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OQS01970.1 - 3.3e-50 170.9 0.1 4.7e-50 170.4 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 OQS01970.1 - 0.00036 19.4 0.1 0.00094 18.1 0.1 1.4 1 1 0 1 1 1 1 Fungal protein kinase FTA2 PF13095.6 OQS01970.1 - 0.0049 16.5 0.2 0.66 9.6 0.0 2.3 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 RIO1 PF01163.22 OQS01970.1 - 0.024 14.2 0.3 0.048 13.3 0.3 1.5 1 0 0 1 1 1 0 RIO1 family Haspin_kinase PF12330.8 OQS01970.1 - 0.035 13.0 0.1 0.067 12.1 0.1 1.4 1 0 0 1 1 1 0 Haspin like kinase domain Pkinase PF00069.25 OQS01971.1 - 3.2e-49 167.7 0.1 4.6e-49 167.2 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQS01971.1 - 8.7e-49 166.1 0.1 1.2e-48 165.7 0.1 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OQS01971.1 - 0.0012 17.7 0.1 0.0017 17.2 0.1 1.3 1 0 0 1 1 1 1 Fungal protein kinase RIO1 PF01163.22 OQS01971.1 - 0.0037 16.9 0.1 0.0064 16.1 0.1 1.4 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.14 OQS01971.1 - 0.0073 15.7 0.1 0.012 15.0 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 OQS01971.1 - 0.034 13.4 0.0 0.056 12.7 0.0 1.3 1 0 0 1 1 1 0 Kinase-like FTA2 PF13095.6 OQS01971.1 - 0.04 13.5 0.1 2.6 7.6 0.0 2.2 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Haspin_kinase PF12330.8 OQS01971.1 - 0.051 12.5 0.1 0.14 11.0 0.0 1.4 1 1 0 1 1 1 0 Haspin like kinase domain APH PF01636.23 OQS01971.1 - 0.064 13.2 0.0 0.096 12.6 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family B9-C2 PF07162.11 OQS01971.1 - 0.12 12.6 0.0 0.22 11.7 0.0 1.4 1 0 0 1 1 1 0 Ciliary basal body-associated, B9 protein C2 PF00168.30 OQS01972.1 - 1.8e-08 34.6 0.0 3.8e-08 33.6 0.0 1.5 1 0 0 1 1 1 1 C2 domain Pkinase PF00069.25 OQS01972.1 - 5e-05 22.8 0.1 0.00012 21.5 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQS01972.1 - 0.00019 20.8 0.0 0.0003 20.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase DUF2574 PF10836.8 OQS01972.1 - 0.095 12.6 0.3 0.25 11.2 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2574) KAR9 PF08580.10 OQS01974.1 - 0.32 9.5 5.9 0.4 9.2 5.9 1.1 1 0 0 1 1 1 0 Yeast cortical protein KAR9 Gp_dh_C PF02800.20 OQS01975.1 - 5.8e-54 182.0 0.1 4.9e-52 175.7 0.1 2.2 1 1 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 OQS01975.1 - 4e-38 129.8 0.0 9e-38 128.7 0.0 1.6 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DapB_N PF01113.20 OQS01975.1 - 0.077 13.1 0.1 0.22 11.7 0.1 2.0 1 1 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus HEV_ORF1 PF02444.16 OQS01976.1 - 0.1 13.1 0.2 0.18 12.4 0.2 1.4 1 0 0 1 1 1 0 Hepatitis E virus ORF-2 (Putative capsid protein) Adeno_E3_14_5 PF04834.12 OQS01977.1 - 0.053 14.1 0.0 0.075 13.6 0.0 1.2 1 0 0 1 1 1 0 Early E3 14.5 kDa protein IF3_N PF05198.16 OQS01978.1 - 2.8e-09 37.1 0.1 4.9e-09 36.3 0.1 1.4 1 0 0 1 1 1 1 Translation initiation factor IF-3, N-terminal domain IF3_C PF00707.22 OQS01978.1 - 0.00048 20.0 0.0 0.0014 18.5 0.0 1.8 1 1 1 2 2 2 1 Translation initiation factor IF-3, C-terminal domain Rotamase_3 PF13616.6 OQS01979.1 - 1.1e-18 67.8 0.0 1.6e-18 67.4 0.0 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase PF00639.21 OQS01979.1 - 2e-15 57.5 0.0 2.8e-15 57.0 0.0 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_2 PF13145.6 OQS01979.1 - 0.0037 18.1 0.0 0.0049 17.7 0.0 1.1 1 0 0 1 1 1 1 PPIC-type PPIASE domain Peptidase_S74 PF13884.6 OQS01980.1 - 6.3e-08 32.8 0.0 9.8e-08 32.2 0.0 1.3 1 0 0 1 1 1 1 Chaperone of endosialidase Exotox-A_cataly PF09009.10 OQS01980.1 - 0.62 9.8 7.0 8 6.2 0.5 2.9 1 1 2 3 3 3 0 Exotoxin A catalytic SCP2 PF02036.17 OQS01981.1 - 4.2e-51 171.6 4.8 3.6e-25 88.4 0.3 2.1 2 0 0 2 2 2 2 SCP-2 sterol transfer family Alkyl_sulf_C PF14864.6 OQS01981.1 - 2.6e-13 50.3 2.1 4.6e-06 26.9 0.0 2.1 2 0 0 2 2 2 2 Alkyl sulfatase C-terminal Hyaluronidase_1 PF07212.11 OQS01981.1 - 0.017 14.4 6.0 0.088 12.1 0.9 2.6 2 1 1 3 3 3 0 Hyaluronidase protein (HylP) DUF1754 PF08555.10 OQS01981.1 - 1.6 9.5 4.6 17 6.3 0.3 2.5 2 0 0 2 2 2 0 Eukaryotic family of unknown function (DUF1754) SRP-alpha_N PF04086.13 OQS01982.1 - 0.36 10.7 18.4 0.46 10.4 18.4 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Asp-B-Hydro_N PF05279.11 OQS01982.1 - 2.2 8.3 13.2 2.8 7.9 13.2 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Di19_C PF14571.6 OQS01982.1 - 3 8.4 8.6 0.33 11.5 3.3 1.9 1 1 1 2 2 2 0 Stress-induced protein Di19, C-terminal GREB1 PF15782.5 OQS01982.1 - 3.9 4.5 5.8 4.2 4.4 5.8 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Pkinase_Tyr PF07714.17 OQS01983.1 - 1.1e-49 169.1 0.0 1.8e-49 168.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OQS01983.1 - 1.9e-46 158.6 0.0 3.6e-46 157.7 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 OQS01983.1 - 0.035 12.9 0.0 0.055 12.2 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase APH PF01636.23 OQS01983.1 - 0.049 13.5 2.0 0.5 10.3 0.0 2.8 3 0 0 3 3 3 0 Phosphotransferase enzyme family Ricin_B_lectin PF00652.22 OQS01984.1 - 1e-23 84.0 12.0 9.2e-12 45.3 4.8 2.5 2 1 0 2 2 2 2 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.6 OQS01984.1 - 1.4e-14 54.5 7.2 0.00034 21.3 0.2 4.3 2 2 3 5 5 5 5 Ricin-type beta-trefoil lectin domain-like Ricin_B_lectin PF00652.22 OQS01985.1 - 3.8e-15 56.3 5.7 4.6e-15 56.0 5.7 1.1 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.6 OQS01985.1 - 1.5e-07 32.0 7.8 7.7e-05 23.3 1.1 2.2 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain-like CDtoxinA PF03498.14 OQS01985.1 - 0.0041 16.7 4.6 0.023 14.3 4.6 1.8 1 1 0 1 1 1 1 Cytolethal distending toxin A/C domain Nucleos_tra2_N PF01773.20 OQS01987.1 - 0.025 15.2 1.6 0.032 14.9 1.6 1.1 1 0 0 1 1 1 0 Na+ dependent nucleoside transporter N-terminus 2TM PF13239.6 OQS01987.1 - 0.031 14.6 0.5 0.038 14.3 0.5 1.1 1 0 0 1 1 1 0 2TM domain UDPGT PF00201.18 OQS01989.1 - 3.4e-05 22.8 0.0 4.3e-05 22.5 0.0 1.1 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase GPHR_N PF12537.8 OQS01989.1 - 0.072 13.2 0.6 0.46 10.6 0.6 2.1 1 1 0 1 1 1 0 The Golgi pH Regulator (GPHR) Family N-terminal Vault_4 PF17796.1 OQS01989.1 - 0.17 12.0 0.0 0.33 11.0 0.0 1.4 1 0 0 1 1 1 0 Major Vault Protein repeat domain VPS9 PF02204.18 OQS01992.1 - 1.1e-27 96.3 0.0 2.6e-27 95.1 0.0 1.7 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain DUF5601 PF18151.1 OQS01992.1 - 0.00088 19.5 0.0 0.0034 17.7 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF5601) TMF_TATA_bd PF12325.8 OQS01992.1 - 0.042 14.1 1.3 0.09 13.0 1.3 1.5 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding TMF_DNA_bd PF12329.8 OQS01992.1 - 0.082 12.9 6.1 0.26 11.3 6.1 1.9 1 1 0 1 1 1 0 TATA element modulatory factor 1 DNA binding DNA_primase_lrg PF04104.14 OQS01992.1 - 0.11 11.9 0.0 0.84 9.0 0.0 2.3 2 0 0 2 2 2 0 Eukaryotic and archaeal DNA primase, large subunit HEAT_2 PF13646.6 OQS01993.1 - 2.7e-07 30.9 1.8 0.009 16.4 0.0 5.0 5 0 0 5 5 5 1 HEAT repeats HEAT PF02985.22 OQS01993.1 - 3e-06 27.0 14.7 0.052 13.8 0.0 7.6 8 0 0 8 8 8 2 HEAT repeat Cnd1 PF12717.7 OQS01993.1 - 0.00012 22.2 6.3 0.031 14.3 0.1 4.1 4 0 0 4 4 4 2 non-SMC mitotic condensation complex subunit 1 RTP1_C1 PF10363.9 OQS01993.1 - 0.0033 17.6 0.4 0.051 13.8 0.1 3.1 4 0 0 4 4 4 1 Required for nuclear transport of RNA pol II C-terminus 1 Vac14_Fab1_bd PF12755.7 OQS01993.1 - 0.017 15.7 2.4 6.2 7.5 0.1 4.7 4 2 1 5 5 5 0 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.6 OQS01993.1 - 0.1 13.2 0.3 0.1 13.2 0.3 3.1 5 0 0 5 5 5 0 HEAT-like repeat Flavodoxin_1 PF00258.25 OQS01994.1 - 1.9e-27 96.2 0.3 5.8e-27 94.7 0.1 1.9 2 0 0 2 2 2 1 Flavodoxin Radical_SAM PF04055.21 OQS01994.1 - 9.9e-26 91.1 0.1 1.8e-25 90.2 0.1 1.5 1 0 0 1 1 1 1 Radical SAM superfamily Wyosine_form PF08608.12 OQS01994.1 - 3.4e-22 78.6 0.0 1e-21 77.0 0.0 1.9 1 0 0 1 1 1 1 Wyosine base formation Flavodoxin_NdrI PF07972.11 OQS01994.1 - 0.0055 16.9 0.0 0.012 15.8 0.0 1.6 1 0 0 1 1 1 1 NrdI Flavodoxin like Hydrolase PF00702.26 OQS01994.1 - 0.099 12.9 0.0 0.26 11.5 0.0 1.7 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase NYD-SP28 PF14772.6 OQS01995.1 - 2e-15 56.6 15.5 2e-15 56.6 15.5 5.0 3 1 2 6 6 6 1 Sperm tail NYD-SP28_assoc PF14775.6 OQS01995.1 - 7.5e-06 26.0 7.7 2.4e-05 24.3 3.7 3.4 2 0 0 2 2 2 1 Sperm tail C-terminal domain SpoIIE PF07228.12 OQS01995.1 - 0.00074 19.5 0.0 0.0036 17.2 0.0 2.1 2 0 0 2 2 2 1 Stage II sporulation protein E (SpoIIE) Melibiase_2_C PF17450.2 OQS01995.1 - 0.096 12.9 0.0 2.1 8.7 0.0 3.1 2 0 0 2 2 2 0 Alpha galactosidase A C-terminal beta sandwich domain DUF4477 PF14780.6 OQS01996.1 - 1.5e-12 47.5 6.3 2e-12 47.2 6.3 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4477) zf-RanBP PF00641.18 OQS01997.1 - 1.9e-06 27.0 0.6 2.8e-06 26.5 0.6 1.2 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others tRNA_bind PF01588.20 OQS01997.1 - 1.3e-05 25.2 2.3 2.1e-05 24.6 2.3 1.4 1 1 0 1 1 1 1 Putative tRNA binding domain KdpC PF02669.15 OQS01997.1 - 0.092 12.6 0.1 0.15 11.9 0.1 1.2 1 0 0 1 1 1 0 K+-transporting ATPase, c chain NDK PF00334.19 OQS01998.1 - 2.6e-27 95.5 0.0 4.5e-27 94.7 0.0 1.3 1 0 0 1 1 1 1 Nucleoside diphosphate kinase Methyltransf_11 PF08241.12 OQS01998.1 - 4.8e-19 68.8 0.0 1.3e-18 67.4 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OQS01998.1 - 1.3e-18 67.5 0.0 5e-18 65.6 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OQS01998.1 - 2.2e-15 57.2 0.0 5.8e-15 55.8 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OQS01998.1 - 1.5e-14 54.0 0.0 3e-14 53.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OQS01998.1 - 4e-12 46.3 0.0 7.8e-12 45.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 OQS01998.1 - 2.6e-08 33.5 0.0 4.8e-08 32.6 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family NodS PF05401.11 OQS01998.1 - 4.3e-05 23.2 0.0 8.4e-05 22.3 0.0 1.4 1 0 0 1 1 1 1 Nodulation protein S (NodS) TehB PF03848.14 OQS01998.1 - 0.00072 19.0 0.0 0.0016 17.9 0.0 1.5 1 0 0 1 1 1 1 Tellurite resistance protein TehB RrnaAD PF00398.20 OQS01998.1 - 0.0094 15.0 0.0 0.017 14.2 0.0 1.3 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase DUF1951 PF09188.10 OQS01998.1 - 0.01 15.8 0.1 0.68 9.9 0.0 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF1951) Methyltransf_8 PF05148.15 OQS01998.1 - 0.026 14.4 0.0 0.078 12.8 0.0 1.8 1 1 0 1 1 1 0 Hypothetical methyltransferase DREV PF05219.12 OQS01998.1 - 0.047 12.8 0.0 0.076 12.1 0.0 1.3 1 0 0 1 1 1 0 DREV methyltransferase MTS PF05175.14 OQS01998.1 - 0.073 12.6 0.0 0.17 11.4 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase small domain Glyco_transf_90 PF05686.12 OQS01999.1 - 2.1e-19 69.7 4.7 6.6e-18 64.8 4.7 2.9 1 1 0 1 1 1 1 Glycosyl transferase family 90 lci PF12197.8 OQS01999.1 - 0.17 11.7 3.4 0.81 9.5 0.2 3.0 3 0 0 3 3 3 0 Bacillus cereus group antimicrobial protein ATP-synt_Eps PF04627.13 OQS02001.1 - 4.8e-16 58.5 1.4 7.5e-16 57.8 1.4 1.3 1 0 0 1 1 1 1 Mitochondrial ATP synthase epsilon chain IBR PF01485.21 OQS02002.1 - 3.2e-13 49.7 46.9 1.7e-07 31.3 16.3 4.3 2 1 2 4 4 4 4 IBR domain, a half RING-finger domain zf-RING_2 PF13639.6 OQS02002.1 - 0.00078 19.7 6.8 0.00078 19.7 6.8 4.4 3 2 0 3 3 3 1 Ring finger domain CEBP_ZZ PF16366.5 OQS02002.1 - 0.013 15.7 3.5 0.013 15.7 3.5 3.5 2 2 0 2 2 2 0 Cytoplasmic polyadenylation element-binding protein ZZ domain FYVE PF01363.21 OQS02002.1 - 7.9 6.7 34.5 0.21 11.7 11.0 3.3 3 0 0 3 3 3 0 FYVE zinc finger Arm PF00514.23 OQS02003.1 - 6.8e-26 89.5 33.3 0.0016 18.4 0.1 17.4 20 0 0 20 20 20 6 Armadillo/beta-catenin-like repeat HEAT PF02985.22 OQS02003.1 - 0.04 14.2 4.5 9.6 6.8 0.0 6.6 7 0 0 7 7 7 0 HEAT repeat HEAT_EZ PF13513.6 OQS02003.1 - 0.3 11.6 10.3 1.1e+02 3.5 0.2 7.3 7 1 0 7 7 7 0 HEAT-like repeat RICTOR_M PF14666.6 OQS02003.1 - 1.6 8.5 5.6 23 4.8 0.3 4.1 3 1 0 4 4 4 0 Rapamycin-insensitive companion of mTOR, middle domain LRR_6 PF13516.6 OQS02005.1 - 3.6e-25 85.8 21.3 0.018 15.1 0.1 10.2 10 0 0 10 10 10 6 Leucine Rich repeat LRR_1 PF00560.33 OQS02005.1 - 1.1e-07 31.4 9.0 9.4 7.2 0.1 8.5 8 0 0 8 8 8 2 Leucine Rich Repeat LRR_4 PF12799.7 OQS02005.1 - 0.00023 21.5 21.8 0.027 14.9 0.3 6.4 4 2 3 7 7 7 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 OQS02005.1 - 0.00039 20.1 25.3 0.39 10.5 7.4 6.4 5 1 1 6 6 6 3 Leucine rich repeat DEP PF00610.21 OQS02005.1 - 0.047 13.8 0.0 0.17 12.0 0.0 1.9 1 0 0 1 1 1 0 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) LRR_4 PF12799.7 OQS02007.1 - 2.8e-22 78.4 31.8 4.7e-09 36.4 7.5 4.6 2 1 3 5 5 5 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 OQS02007.1 - 1.8e-21 75.6 13.8 8.4e-09 35.1 0.0 3.6 2 1 1 3 3 3 3 Leucine rich repeat LRR_9 PF14580.6 OQS02007.1 - 3.9e-08 33.0 8.0 0.00012 21.7 4.3 2.3 1 1 0 2 2 2 2 Leucine-rich repeat LRR_1 PF00560.33 OQS02007.1 - 4.4e-05 23.5 9.9 5.4 8.0 0.8 5.8 6 0 0 6 6 6 2 Leucine Rich Repeat LRR_5 PF13306.6 OQS02007.1 - 0.009 16.0 0.5 3.6 7.5 0.2 2.4 2 1 0 2 2 2 2 BspA type Leucine rich repeat region (6 copies) MFS_1 PF07690.16 OQS02008.1 - 9e-22 77.5 38.0 2.3e-11 43.2 15.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Nodulin-like PF06813.13 OQS02008.1 - 2.6e-06 27.1 2.9 2.6e-06 27.1 2.9 2.9 2 1 0 3 3 3 1 Nodulin-like ATP-synt_ab PF00006.25 OQS02009.1 - 1.6e-61 207.7 0.0 2.2e-61 207.2 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 OQS02009.1 - 1.5e-22 79.9 1.6 3.1e-22 78.9 1.6 1.6 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain AAA_19 PF13245.6 OQS02009.1 - 0.012 16.0 1.0 0.1 12.9 0.3 2.3 2 0 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 OQS02009.1 - 0.02 14.8 0.1 0.048 13.6 0.1 1.6 1 0 0 1 1 1 0 RsgA GTPase AAA PF00004.29 OQS02009.1 - 0.094 13.1 0.1 1.4 9.4 0.0 2.4 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Metallophos PF00149.28 OQS02010.1 - 4.3e-31 109.0 0.6 8.7e-31 108.0 0.6 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase FYVE PF01363.21 OQS02010.1 - 1.2e-12 47.8 11.2 1.2e-12 47.8 11.2 1.9 2 0 0 2 2 2 1 FYVE zinc finger EF-hand_7 PF13499.6 OQS02010.1 - 1e-05 25.9 3.2 0.00026 21.4 1.9 3.4 3 1 1 4 4 4 2 EF-hand domain pair EF-hand_8 PF13833.6 OQS02010.1 - 0.00011 22.0 2.5 0.033 14.0 0.2 3.5 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_1 PF00036.32 OQS02010.1 - 0.0058 16.1 1.0 0.41 10.3 0.0 3.7 3 0 0 3 3 3 1 EF hand EF-hand_6 PF13405.6 OQS02010.1 - 0.041 13.8 3.9 16 5.7 0.3 4.4 5 0 0 5 5 5 0 EF-hand domain PH_8 PF15409.6 OQS02010.1 - 0.047 14.0 0.2 3 8.2 0.0 2.7 2 0 0 2 2 2 0 Pleckstrin homology domain PPP5 PF08321.12 OQS02010.1 - 0.11 12.7 0.0 0.36 11.1 0.0 1.8 1 0 0 1 1 1 0 PPP5 TPR repeat region FYVE_2 PF02318.16 OQS02010.1 - 4.3 7.6 8.2 9.5 6.5 8.2 1.5 1 0 0 1 1 1 0 FYVE-type zinc finger RRM_1 PF00076.22 OQS02011.1 - 1.5e-06 28.0 0.0 3.2e-06 26.9 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) API5 PF05918.11 OQS02011.1 - 0.0029 16.5 0.0 0.0029 16.5 0.0 2.1 2 1 1 3 3 3 1 Apoptosis inhibitory protein 5 (API5) DUF2870 PF11069.8 OQS02013.1 - 7.6e-41 138.4 1.0 1.3e-40 137.7 1.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2870) Taeniidae_ag PF05596.11 OQS02013.1 - 0.0045 16.9 0.5 0.093 12.7 0.0 2.7 3 0 0 3 3 3 1 Taeniidae antigen Elongin_A PF06881.11 OQS02013.1 - 0.081 13.5 0.9 0.21 12.1 0.9 1.7 1 1 0 1 1 1 0 RNA polymerase II transcription factor SIII (Elongin) subunit A Beta_elim_lyase PF01212.21 OQS02014.1 - 0.049 12.9 0.0 0.062 12.6 0.0 1.1 1 0 0 1 1 1 0 Beta-eliminating lyase TTL PF03133.15 OQS02015.1 - 1.7e-75 253.9 1.7 2.3e-75 253.5 0.1 1.9 1 1 0 2 2 2 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 OQS02015.1 - 7.4e-08 32.0 3.7 6.7e-06 25.5 0.0 3.8 3 1 1 4 4 4 1 YheC/D like ATP-grasp DUF1980 PF09323.10 OQS02015.1 - 0.028 14.3 3.8 0.052 13.4 3.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) ATP-grasp_3 PF02655.14 OQS02015.1 - 0.03 14.4 0.0 0.19 11.7 0.0 2.1 2 0 0 2 2 2 0 ATP-grasp domain ATPgrasp_ST PF14397.6 OQS02015.1 - 0.053 12.8 0.0 0.54 9.4 0.0 2.3 2 1 1 3 3 3 0 Sugar-transfer associated ATP-grasp CDP-OH_P_transf PF01066.21 OQS02016.1 - 1.5e-12 48.1 0.7 1.5e-12 48.1 0.7 2.3 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase PX PF00787.24 OQS02017.1 - 1.9e-08 34.3 0.1 3.4e-08 33.5 0.1 1.4 1 0 0 1 1 1 1 PX domain ADH_N PF08240.12 OQS02018.1 - 6.3e-43 145.1 19.5 1.5e-24 86.0 7.0 2.3 2 0 0 2 2 2 2 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 OQS02018.1 - 2.3e-19 69.6 0.1 5.6e-19 68.4 0.1 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 OQS02018.1 - 2.6e-13 51.2 0.1 2.9e-10 41.3 0.1 2.2 2 0 0 2 2 2 2 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 OQS02018.1 - 0.00033 20.0 0.2 0.0021 17.4 0.0 2.1 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain zf-C2H2_12 PF18658.1 OQS02018.1 - 0.0046 16.5 0.1 1.5 8.5 0.0 2.5 2 0 0 2 2 2 2 Zinc-finger C2H2-type 2-Hacid_dh_C PF02826.19 OQS02018.1 - 0.023 14.1 0.1 0.041 13.2 0.1 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DUF983 PF06170.12 OQS02018.1 - 0.1 13.0 0.0 8.9 6.8 0.0 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF983) Yeast_MT PF11403.8 OQS02018.1 - 9.6 6.9 17.2 7.8 7.2 6.9 2.8 2 0 0 2 2 2 0 Yeast metallothionein Hist_deacetyl PF00850.19 OQS02019.1 - 2.6e-28 99.4 0.0 4.5e-28 98.6 0.0 1.4 2 0 0 2 2 2 1 Histone deacetylase domain Ank_2 PF12796.7 OQS02020.1 - 7.7e-24 84.1 4.0 1.4e-07 32.0 0.2 4.1 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQS02020.1 - 1.3e-21 76.6 3.6 1.8e-07 31.6 0.0 4.6 3 1 1 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQS02020.1 - 8.9e-17 59.5 6.3 0.0055 17.1 0.0 7.4 7 0 0 7 7 7 4 Ankyrin repeat Ank_5 PF13857.6 OQS02020.1 - 2.7e-14 53.0 5.5 0.11 12.8 0.1 5.5 4 1 1 5 5 5 5 Ankyrin repeats (many copies) Ank PF00023.30 OQS02020.1 - 1.4e-11 44.2 12.6 0.054 14.0 0.0 7.2 6 1 1 7 7 7 5 Ankyrin repeat WD40 PF00400.32 OQS02021.1 - 1.5e-16 60.5 18.1 2.8e-05 24.8 0.1 6.3 6 1 0 6 6 6 3 WD domain, G-beta repeat NHL PF01436.21 OQS02021.1 - 0.00037 20.4 0.9 0.13 12.4 0.0 3.9 3 0 0 3 3 3 1 NHL repeat ANAPC4_WD40 PF12894.7 OQS02021.1 - 0.00071 19.8 0.1 1.5 9.2 0.0 3.7 2 2 2 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain PQQ_3 PF13570.6 OQS02021.1 - 0.0019 18.6 7.8 1.6 9.3 0.1 4.7 6 0 0 6 6 6 2 PQQ-like domain Nup160 PF11715.8 OQS02021.1 - 0.091 11.4 0.0 0.85 8.2 0.0 2.0 2 0 0 2 2 2 0 Nucleoporin Nup120/160 PQQ PF01011.21 OQS02021.1 - 0.17 11.9 0.8 33 4.6 0.1 3.0 2 0 0 2 2 2 0 PQQ enzyme repeat LRR_4 PF12799.7 OQS02022.1 - 4.3e-05 23.8 22.3 0.025 15.0 2.1 8.9 8 3 1 9 9 9 2 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 OQS02022.1 - 9.7e-05 22.3 11.0 0.84 9.6 0.2 4.5 3 2 1 4 4 4 2 BspA type Leucine rich repeat region (6 copies) CDtoxinA PF03498.14 OQS02022.1 - 2.7 7.6 15.4 59 3.2 0.0 4.7 2 2 2 4 4 4 0 Cytolethal distending toxin A/C domain Aa_trans PF01490.18 OQS02023.1 - 1.9e-36 125.7 27.7 2.4e-36 125.3 27.7 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Bap31 PF05529.12 OQS02024.1 - 4.2e-17 62.3 3.9 6.2e-17 61.7 3.9 1.3 1 1 0 1 1 1 1 Bap31/Bap29 transmembrane region Pkinase PF00069.25 OQS02025.1 - 1.1e-21 77.4 0.0 1.3e-21 77.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQS02025.1 - 4e-16 59.1 0.0 9.1e-16 57.9 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 OQS02025.1 - 0.032 14.1 0.0 0.047 13.6 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family CRCB PF02537.15 OQS02026.1 - 0.042 14.2 20.4 0.61 10.4 10.4 2.5 2 1 0 2 2 2 0 CrcB-like protein, Camphor Resistance (CrcB) DHHA2 PF02833.14 OQS02027.1 - 2.3e-13 50.5 0.0 5.8e-13 49.2 0.0 1.6 1 0 0 1 1 1 1 DHHA2 domain DHH PF01368.20 OQS02027.1 - 3.1e-09 37.0 0.6 2.2e-08 34.3 0.5 2.3 2 0 0 2 2 2 1 DHH family PAN_4 PF14295.6 OQS02027.1 - 2.5 8.1 11.3 0.43 10.5 0.2 3.4 3 0 0 3 3 3 0 PAN domain Ank_2 PF12796.7 OQS02028.1 - 4.5e-48 161.8 18.3 1.2e-15 57.8 0.4 3.9 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQS02028.1 - 6.2e-37 125.5 5.0 1.1e-15 57.8 0.0 4.7 4 0 0 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQS02028.1 - 9.2e-30 99.4 5.1 2.5e-05 24.3 0.0 6.8 6 0 0 6 6 6 6 Ankyrin repeat Ank PF00023.30 OQS02028.1 - 2.3e-25 87.9 7.5 7.5e-06 26.2 0.1 5.8 5 0 0 5 5 5 5 Ankyrin repeat Ank_5 PF13857.6 OQS02028.1 - 5.8e-25 87.0 9.5 1e-06 28.8 0.0 6.3 2 1 4 6 6 6 5 Ankyrin repeats (many copies) Peptidase_S10 PF00450.22 OQS02029.1 - 9.3e-124 414.0 1.3 1.2e-123 413.7 1.3 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Hydrolase_4 PF12146.8 OQS02029.1 - 0.034 13.4 0.2 2.7 7.2 0.0 2.4 2 1 0 2 2 2 0 Serine aminopeptidase, S33 Ank_2 PF12796.7 OQS02030.1 - 3.6e-200 649.2 55.9 4e-16 59.4 0.4 17.8 4 3 12 17 17 17 17 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQS02030.1 - 1.2e-145 472.2 29.4 2.4e-10 40.8 0.1 26.0 8 6 21 30 30 30 26 Ankyrin repeats (many copies) Ank PF00023.30 OQS02030.1 - 4.2e-143 460.2 93.6 1.2e-06 28.6 0.0 34.9 34 3 2 36 36 34 30 Ankyrin repeat Ank_3 PF13606.6 OQS02030.1 - 2.7e-125 392.9 42.8 0.0022 18.4 0.0 35.7 35 1 1 36 36 36 28 Ankyrin repeat Ank_5 PF13857.6 OQS02030.1 - 2.7e-107 349.4 58.6 7e-10 39.0 0.1 25.7 9 6 18 27 27 27 26 Ankyrin repeats (many copies) Pkinase_Tyr PF07714.17 OQS02030.1 - 1.3e-25 90.2 0.0 1e-11 44.6 0.0 2.7 2 1 1 3 3 3 2 Protein tyrosine kinase Pkinase PF00069.25 OQS02030.1 - 1.2e-19 70.8 0.0 2.9e-17 62.9 0.0 2.4 1 1 0 1 1 1 1 Protein kinase domain Imm_superinfect PF14373.6 OQS02030.1 - 0.0012 18.7 4.5 17 5.4 0.0 9.2 12 0 0 12 12 12 0 Superinfection immunity protein Amidohydro_3 PF07969.11 OQS02030.1 - 0.0036 16.8 10.4 8.1 5.8 0.1 6.5 4 2 3 7 7 7 1 Amidohydrolase family DUF4988 PF16378.5 OQS02030.1 - 0.013 15.2 3.4 42 3.7 0.0 7.0 7 2 2 9 9 9 0 Domain of unknown function Rho_GDI PF02115.17 OQS02030.1 - 0.16 11.7 0.0 0.3 10.8 0.0 1.4 1 0 0 1 1 1 0 RHO protein GDP dissociation inhibitor Pyridoxal_deC PF00282.19 OQS02030.1 - 0.45 9.2 4.3 39 2.8 0.0 5.4 7 0 0 7 7 7 0 Pyridoxal-dependent decarboxylase conserved domain DUF4226 PF10774.9 OQS02030.1 - 1.6 9.1 3.6 9.9 6.5 0.1 3.9 5 0 0 5 5 5 0 Domain of unknown function (DUF4226) Peptidase_C69 PF03577.15 OQS02031.1 - 1.1e-35 123.4 0.0 6.4e-35 120.8 0.0 2.1 1 1 0 1 1 1 1 Peptidase family C69 DUF707 PF05212.12 OQS02031.1 - 0.021 14.1 0.7 0.035 13.4 0.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF707) Pkinase_Tyr PF07714.17 OQS02032.1 - 7.1e-109 363.1 0.0 1.1e-53 182.2 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 OQS02032.1 - 1.2e-76 257.5 0.0 1.1e-37 129.9 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_fungal PF17667.1 OQS02032.1 - 0.0009 18.1 0.0 0.75 8.5 0.0 2.2 2 0 0 2 2 2 2 Fungal protein kinase Kdo PF06293.14 OQS02032.1 - 0.0034 16.8 0.0 0.55 9.5 0.0 2.2 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 OQS02032.1 - 0.034 13.1 0.0 12 4.7 0.0 2.9 3 0 0 3 3 3 0 Haspin like kinase domain APH PF01636.23 OQS02032.1 - 0.16 11.8 0.0 18 5.2 0.0 2.4 2 0 0 2 2 2 0 Phosphotransferase enzyme family GDP_Man_Dehyd PF16363.5 OQS02033.1 - 7.5e-32 111.0 0.0 1.7e-31 109.8 0.0 1.5 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 OQS02033.1 - 1.4e-27 96.7 0.0 1.9e-27 96.3 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 OQS02033.1 - 0.0048 16.1 0.0 0.028 13.6 0.0 1.8 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein PP2C PF00481.21 OQS02034.1 - 5.9e-77 258.8 0.2 7.5e-77 258.4 0.2 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 OQS02034.1 - 7.5e-07 29.0 0.0 1.3e-06 28.2 0.0 1.4 1 1 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 OQS02034.1 - 0.0016 18.4 0.2 0.083 12.8 0.0 2.1 2 0 0 2 2 2 2 Stage II sporulation protein E (SpoIIE) WW PF00397.26 OQS02036.1 - 0.00047 20.2 4.6 0.00059 19.9 3.0 2.0 2 1 0 2 2 2 1 WW domain Olduvai PF06758.13 OQS02036.1 - 0.068 13.4 0.1 0.11 12.8 0.1 1.4 1 0 0 1 1 1 0 Olduvai domain Cyclin_N PF00134.23 OQS02037.1 - 5.3e-30 103.8 0.2 1.2e-29 102.7 0.1 1.6 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 OQS02037.1 - 0.013 15.6 2.4 0.013 15.5 0.5 1.9 2 0 0 2 2 2 0 Cyclin, C-terminal domain DUF4234 PF14018.6 OQS02038.1 - 0.00099 19.2 5.9 0.0029 17.7 0.7 3.4 3 0 0 3 3 3 1 Domain of unknown function (DUF4234) HSF_DNA-bind PF00447.17 OQS02039.1 - 2.4e-29 101.8 0.9 3.7e-29 101.2 0.3 1.6 2 0 0 2 2 2 1 HSF-type DNA-binding Ank PF00023.30 OQS02039.1 - 0.00073 19.9 0.6 0.35 11.4 0.1 2.8 3 0 0 3 3 3 1 Ankyrin repeat Ank_4 PF13637.6 OQS02039.1 - 0.0075 16.8 0.0 0.017 15.7 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 OQS02039.1 - 0.008 16.7 0.0 0.017 15.7 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OQS02039.1 - 0.014 15.9 0.2 0.97 10.2 0.0 2.7 2 0 0 2 2 2 0 Ankyrin repeat DUF4431 PF14485.6 OQS02039.1 - 0.12 12.2 0.1 4.1 7.3 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4431) Peptidase_A2E PF12382.8 OQS02039.1 - 0.12 12.4 0.0 0.27 11.2 0.0 1.6 1 0 0 1 1 1 0 Retrotransposon peptidase DUF4988 PF16378.5 OQS02039.1 - 0.17 11.5 0.0 0.41 10.3 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function TPR_2 PF07719.17 OQS02040.1 - 2.3e-16 58.5 0.1 2.4e-07 30.4 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 OQS02040.1 - 2.7e-13 49.1 0.0 1.6e-07 30.9 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 OQS02040.1 - 1.7e-12 47.5 5.3 2.7e-08 34.0 0.6 3.3 2 1 2 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.6 OQS02040.1 - 9.7e-09 34.7 1.0 0.00033 20.5 0.0 2.9 3 0 0 3 3 2 2 Tetratricopeptide repeat TPR_16 PF13432.6 OQS02040.1 - 2.6e-08 34.4 0.0 7e-06 26.6 0.1 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 OQS02040.1 - 5.6e-08 32.4 0.0 2.2e-05 24.3 0.0 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.6 OQS02040.1 - 8.7e-07 28.5 0.8 6.1e-06 25.8 0.4 2.5 1 1 1 2 2 2 1 TPR repeat TPR_19 PF14559.6 OQS02040.1 - 7.8e-06 26.3 0.0 5.5e-05 23.6 0.1 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.6 OQS02040.1 - 2.4e-05 24.4 0.5 0.61 10.6 0.1 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 OQS02040.1 - 4.4e-05 24.0 0.1 0.00099 19.7 0.0 3.2 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_10 PF13374.6 OQS02040.1 - 8.1e-05 22.4 1.7 0.035 14.0 0.1 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.6 OQS02040.1 - 0.0039 17.7 0.0 0.23 12.2 0.0 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.6 OQS02040.1 - 0.031 14.4 0.1 0.34 11.1 0.0 2.3 1 1 1 2 2 2 0 Tetratricopeptide repeat ANAPC3 PF12895.7 OQS02040.1 - 0.077 13.2 1.1 0.25 11.6 0.2 2.3 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_4 PF07721.14 OQS02040.1 - 0.085 13.5 3.5 1.5 9.7 0.0 3.4 4 0 0 4 4 3 0 Tetratricopeptide repeat IQ PF00612.27 OQS02040.1 - 0.086 12.7 1.8 0.11 12.3 0.2 2.1 2 0 0 2 2 2 0 IQ calmodulin-binding motif Transket_pyr PF02779.24 OQS02041.1 - 3e-46 157.3 0.0 4.7e-46 156.7 0.0 1.2 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 OQS02041.1 - 2.9e-43 146.7 0.4 7.8e-43 145.3 0.2 1.9 2 0 0 2 2 2 1 Transketolase, C-terminal domain PFOR_II PF17147.4 OQS02041.1 - 0.0016 18.7 0.0 0.004 17.4 0.0 1.7 1 0 0 1 1 1 1 Pyruvate:ferredoxin oxidoreductase core domain II HHH PF00633.23 OQS02042.1 - 0.002 17.9 0.5 0.0044 16.8 0.5 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix motif DUF2336 PF10098.9 OQS02042.1 - 0.0038 16.8 0.1 0.0047 16.4 0.1 1.3 1 0 0 1 1 1 1 Uncharacterised protein conserved in bacteria (DUF2336) Pkinase PF00069.25 OQS02043.1 - 5e-65 219.5 0.0 8e-65 218.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQS02043.1 - 2.8e-29 102.2 0.1 2.5e-28 99.1 0.1 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase DEP PF00610.21 OQS02043.1 - 2.2e-17 62.9 0.2 8.1e-17 61.1 0.0 2.1 2 0 0 2 2 2 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) START PF01852.19 OQS02043.1 - 5.7e-08 32.4 0.0 9e-07 28.5 0.0 2.2 2 0 0 2 2 2 1 START domain Pkinase_C PF00433.24 OQS02043.1 - 8.1e-05 23.2 16.1 0.00013 22.6 4.1 2.8 2 0 0 2 2 2 1 Protein kinase C terminal domain Kdo PF06293.14 OQS02043.1 - 0.00031 20.2 0.2 0.00086 18.7 0.2 1.8 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 OQS02043.1 - 0.0047 16.3 0.3 0.02 14.2 0.0 2.0 2 0 0 2 2 2 1 Kinase-like RIO1 PF01163.22 OQS02043.1 - 0.046 13.3 0.2 0.089 12.4 0.2 1.4 1 0 0 1 1 1 0 RIO1 family Haspin_kinase PF12330.8 OQS02043.1 - 0.067 12.1 0.0 0.13 11.2 0.0 1.4 1 0 0 1 1 1 0 Haspin like kinase domain YukC PF10140.9 OQS02043.1 - 0.071 11.9 0.0 0.16 10.8 0.0 1.5 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukC DVL PF08137.12 OQS02043.1 - 0.2 11.6 0.6 0.36 10.7 0.6 1.4 1 0 0 1 1 1 0 DVL family APH PF01636.23 OQS02043.1 - 0.2 11.5 0.7 1.1 9.2 0.8 1.9 1 1 1 2 2 2 0 Phosphotransferase enzyme family Peptidase_S10 PF00450.22 OQS02044.1 - 5.9e-120 401.5 0.9 6.8e-120 401.3 0.9 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase DUF1180 PF06679.12 OQS02045.1 - 0.086 13.2 0.0 0.11 13.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) Peptidase_S8 PF00082.22 OQS02045.1 - 0.098 11.9 0.0 0.14 11.4 0.0 1.2 1 0 0 1 1 1 0 Subtilase family Stevor PF17410.2 OQS02045.1 - 0.099 12.2 0.0 0.12 11.9 0.0 1.1 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame DUF5305 PF17231.2 OQS02045.1 - 0.12 11.8 0.1 0.16 11.4 0.1 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5305) Pro-kuma_activ PF09286.11 OQS02046.1 - 1.3e-20 74.2 0.3 2e-20 73.6 0.3 1.2 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain ABC_membrane PF00664.23 OQS02048.1 - 1.1e-30 107.2 11.8 1.3e-30 107.0 11.8 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 OQS02048.1 - 0.00024 21.7 0.4 0.00044 20.8 0.4 1.5 1 0 0 1 1 1 1 ABC transporter TPR_1 PF00515.28 OQS02049.1 - 1.8e-21 75.0 11.9 1.9e-08 33.8 0.0 4.7 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.17 OQS02049.1 - 4.5e-17 60.7 13.7 2.8e-06 27.0 0.0 4.7 5 0 0 5 5 5 3 Tetratricopeptide repeat STI1 PF17830.1 OQS02049.1 - 5.5e-16 58.3 21.8 2.8e-12 46.4 1.0 2.7 2 0 0 2 2 2 2 STI1 domain TPR_8 PF13181.6 OQS02049.1 - 1.1e-12 47.1 7.6 9.7e-05 22.3 0.0 4.6 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_11 PF13414.6 OQS02049.1 - 4e-12 45.6 15.5 0.00091 18.9 0.1 4.8 3 1 2 5 5 5 4 TPR repeat TPR_7 PF13176.6 OQS02049.1 - 4e-11 42.1 2.5 0.00074 19.4 0.1 4.1 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_14 PF13428.6 OQS02049.1 - 3.2e-10 40.0 1.7 0.00029 21.4 0.1 4.7 2 1 2 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.6 OQS02049.1 - 5.6e-10 39.7 4.6 0.00028 21.5 0.2 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.6 OQS02049.1 - 1.5e-07 31.8 7.6 0.016 15.7 0.6 4.4 3 1 0 4 4 4 2 Tetratricopeptide repeat SGT1 PF07093.11 OQS02049.1 - 5.7e-07 28.4 0.1 8.5e-07 27.8 0.1 1.2 1 0 0 1 1 1 1 SGT1 protein TPR_17 PF13431.6 OQS02049.1 - 1.9e-06 27.8 2.4 0.0015 18.8 0.0 4.6 5 0 0 5 5 5 1 Tetratricopeptide repeat SGTA_dimer PF16546.5 OQS02049.1 - 1.5e-05 24.7 0.1 4.2e-05 23.2 0.0 1.8 2 0 0 2 2 2 1 Homodimerisation domain of SGTA TPR_12 PF13424.6 OQS02049.1 - 1.8e-05 24.9 7.5 0.00034 20.9 0.8 2.8 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.6 OQS02049.1 - 0.0002 21.5 0.1 0.003 17.7 0.0 2.7 2 1 1 3 3 2 1 Tetratricopeptide repeat TPR_10 PF13374.6 OQS02049.1 - 0.0055 16.5 3.5 15 5.6 0.2 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat XPC-binding PF09280.11 OQS02049.1 - 0.029 14.1 14.9 0.12 12.1 6.7 3.9 3 1 1 4 4 4 0 XPC-binding domain TPR_6 PF13174.6 OQS02049.1 - 0.33 11.7 6.3 16 6.4 0.1 3.8 4 0 0 4 4 2 0 Tetratricopeptide repeat BTAD PF03704.17 OQS02049.1 - 0.69 10.3 4.1 36 4.8 0.2 3.2 3 0 0 3 3 3 0 Bacterial transcriptional activator domain Com_YlbF PF06133.11 OQS02049.1 - 1.2 9.8 7.3 1.4 9.5 0.0 2.9 2 1 0 2 2 2 0 Control of competence regulator ComK, YlbF/YmcA MIT PF04212.18 OQS02049.1 - 1.5 9.0 10.7 6.4 6.9 1.8 3.5 2 1 1 3 3 3 0 MIT (microtubule interacting and transport) domain DUF4199 PF13858.6 OQS02049.1 - 1.7 9.0 5.6 0.23 11.8 0.6 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF4199) Choline_transpo PF04515.12 OQS02050.1 - 4.2e-81 272.7 26.6 4.2e-81 272.7 26.6 3.2 3 0 0 3 3 3 2 Plasma-membrane choline transporter AveC_like PF17198.4 OQS02050.1 - 3.7 6.9 15.8 0.017 14.6 2.6 2.7 3 0 0 3 3 3 0 Spirocyclase AveC-like Cytokin_check_N PF10407.9 OQS02051.1 - 0.0016 18.3 0.0 0.0054 16.7 0.0 1.9 2 0 0 2 2 2 1 Cdc14 phosphatase binding protein N-terminus Arm PF00514.23 OQS02051.1 - 0.0098 15.9 2.6 28 4.9 0.0 4.6 4 0 0 4 4 4 2 Armadillo/beta-catenin-like repeat DUF1556 PF07590.11 OQS02051.1 - 0.056 13.7 0.0 0.38 11.1 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1556) Cnd1 PF12717.7 OQS02051.1 - 1.5 8.8 9.3 0.91 9.6 1.1 3.6 3 1 0 3 3 3 0 non-SMC mitotic condensation complex subunit 1 MAM33 PF02330.16 OQS02052.1 - 6.9e-42 143.8 10.6 8e-42 143.6 10.6 1.0 1 0 0 1 1 1 1 Mitochondrial glycoprotein Cas_Cas2CT1978 PF09707.10 OQS02052.1 - 0.072 13.2 0.0 1 9.4 0.0 2.1 2 0 0 2 2 2 0 CRISPR-associated protein (Cas_Cas2CT1978) PPR_2 PF13041.6 OQS02053.1 - 5.1e-08 33.0 3.0 5.2e-05 23.3 0.5 3.2 2 1 2 4 4 4 3 PPR repeat family MRP-S27 PF10037.9 OQS02053.1 - 0.00011 21.2 0.9 0.00017 20.6 0.9 1.3 1 1 0 1 1 1 1 Mitochondrial 28S ribosomal protein S27 Mic1 PF07035.12 OQS02053.1 - 0.0035 17.1 2.0 0.0088 15.8 0.4 2.2 2 0 0 2 2 2 1 Colon cancer-associated protein Mic1-like PPR_long PF17177.4 OQS02053.1 - 0.0073 15.7 0.5 0.062 12.7 0.4 1.9 1 1 1 2 2 2 2 Pentacotripeptide-repeat region of PRORP RPM2 PF08579.11 OQS02053.1 - 0.017 15.5 1.2 0.062 13.7 0.4 2.3 1 1 1 2 2 2 0 Mitochondrial ribonuclease P subunit (RPM2) PPR PF01535.20 OQS02053.1 - 0.21 11.9 0.8 20 5.7 0.0 3.7 4 0 0 4 4 4 0 PPR repeat PPR_3 PF13812.6 OQS02053.1 - 1 9.5 4.6 2.6 8.2 0.5 2.9 2 1 0 3 3 3 0 Pentatricopeptide repeat domain MRP-S27 PF10037.9 OQS02054.1 - 2e-05 23.7 5.4 0.00015 20.8 0.2 2.1 1 1 1 2 2 2 2 Mitochondrial 28S ribosomal protein S27 PPR_2 PF13041.6 OQS02054.1 - 2.5e-05 24.4 0.1 0.018 15.2 0.0 3.6 3 1 1 4 4 4 2 PPR repeat family PPR_3 PF13812.6 OQS02054.1 - 3.6e-05 23.7 0.1 0.0095 16.0 0.0 3.4 2 2 2 4 4 4 3 Pentatricopeptide repeat domain PPR PF01535.20 OQS02054.1 - 0.00061 19.9 0.0 0.11 12.9 0.0 3.5 4 0 0 4 4 4 1 PPR repeat PPR_long PF17177.4 OQS02054.1 - 0.0007 19.0 1.1 0.0048 16.3 0.6 2.0 1 1 1 2 2 2 2 Pentacotripeptide-repeat region of PRORP TPR_19 PF14559.6 OQS02054.1 - 0.0022 18.5 0.3 0.017 15.6 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat AAA_lid_9 PF17871.1 OQS02054.1 - 0.0029 17.5 0.2 0.0029 17.5 0.2 2.1 2 0 0 2 2 2 1 AAA lid domain TPR_14 PF13428.6 OQS02054.1 - 0.0043 17.8 0.2 0.058 14.2 0.0 2.7 3 0 0 3 3 2 1 Tetratricopeptide repeat RFC1 PF08519.12 OQS02054.1 - 0.028 14.6 1.2 4.2 7.5 0.0 2.6 2 1 1 3 3 3 0 Replication factor RFC1 C terminal domain Dpoe2NT PF12213.8 OQS02054.1 - 0.038 14.3 0.4 0.13 12.6 0.4 1.9 1 0 0 1 1 1 0 DNA polymerases epsilon N terminal TPR_6 PF13174.6 OQS02054.1 - 0.067 13.8 1.4 9.4 7.1 0.1 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 OQS02054.1 - 0.088 13.1 0.6 0.81 10.0 0.1 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF1707 PF08044.11 OQS02054.1 - 0.092 12.8 0.0 0.34 11.0 0.2 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1707) RSD-2 PF07547.13 OQS02054.1 - 0.26 11.8 2.3 12 6.5 0.5 2.4 2 0 0 2 2 2 0 RSD-2 N-terminal domain Histone_HNS PF00816.21 OQS02054.1 - 2.6 8.9 4.7 0.64 10.9 0.3 2.2 2 1 0 2 2 2 0 H-NS histone family Pkinase_Tyr PF07714.17 OQS02055.1 - 1.9e-28 99.4 0.0 3.1e-28 98.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OQS02055.1 - 7.8e-21 74.6 0.0 1.3e-20 73.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain C2 PF00168.30 OQS02055.1 - 2.5e-06 27.7 0.0 6.1e-06 26.5 0.0 1.7 1 0 0 1 1 1 1 C2 domain CENP-H PF05837.12 OQS02055.1 - 0.019 15.4 3.1 0.042 14.3 3.1 1.5 1 0 0 1 1 1 0 Centromere protein H (CENP-H) Kdo PF06293.14 OQS02055.1 - 0.02 14.2 0.1 0.038 13.4 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family SlyX PF04102.12 OQS02055.1 - 0.039 14.6 0.6 0.1 13.2 0.6 1.8 1 0 0 1 1 1 0 SlyX zf-RING_10 PF16685.5 OQS02055.1 - 0.098 12.8 1.0 0.3 11.3 1.0 1.8 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-RanBP PF00641.18 OQS02055.1 - 0.099 12.0 3.8 0.18 11.2 3.8 1.4 1 0 0 1 1 1 0 Zn-finger in Ran binding protein and others SHE3 PF17078.5 OQS02055.1 - 0.15 11.8 4.5 0.26 11.0 4.5 1.3 1 0 0 1 1 1 0 SWI5-dependent HO expression protein 3 AAA_23 PF13476.6 OQS02055.1 - 0.52 10.8 5.4 0.96 9.9 5.4 1.3 1 0 0 1 1 1 0 AAA domain HALZ PF02183.18 OQS02055.1 - 4 7.7 9.6 0.078 13.2 1.7 2.3 3 0 0 3 3 3 0 Homeobox associated leucine zipper Ank_2 PF12796.7 OQS02056.1 - 9.7e-19 67.7 3.9 3.5e-12 46.7 0.1 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 OQS02056.1 - 1.2e-18 66.6 2.5 6.2e-07 29.6 0.1 3.4 3 0 0 3 3 3 3 Ankyrin repeat Ank_4 PF13637.6 OQS02056.1 - 1.1e-17 64.1 1.9 3.2e-06 27.6 0.1 4.0 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQS02056.1 - 5.2e-17 60.2 0.6 0.00032 20.9 0.0 3.5 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.6 OQS02056.1 - 2.6e-16 59.4 1.5 6e-07 29.6 0.5 2.4 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 OQS02057.1 - 8.8e-60 199.3 23.9 2.3e-15 56.9 0.9 6.6 2 2 5 7 7 7 7 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OQS02057.1 - 2.3e-50 162.7 25.0 6.3e-05 23.1 0.0 12.1 12 0 0 12 12 12 11 Ankyrin repeat Ank_4 PF13637.6 OQS02057.1 - 2.4e-47 158.7 17.3 2.8e-10 40.5 0.1 8.1 6 1 2 8 8 8 7 Ankyrin repeats (many copies) Ank PF00023.30 OQS02057.1 - 2.6e-42 141.5 39.5 2.9e-05 24.3 0.3 12.1 10 2 2 12 12 12 11 Ankyrin repeat Ank_5 PF13857.6 OQS02057.1 - 3.3e-39 132.4 26.9 2.8e-10 40.2 0.4 9.4 3 2 8 11 11 11 9 Ankyrin repeats (many copies) TPR_2 PF07719.17 OQS02058.1 - 7e-13 47.6 8.6 0.00029 20.7 0.3 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.28 OQS02058.1 - 3.4e-12 45.6 8.8 3e-05 23.7 0.3 3.3 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.6 OQS02058.1 - 1.1e-09 37.7 7.7 0.0082 16.3 0.2 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_17 PF13431.6 OQS02058.1 - 2.3e-06 27.6 7.5 0.032 14.6 0.6 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_20 PF14561.6 OQS02058.1 - 0.00019 21.7 0.3 0.00064 20.0 0.0 2.0 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.6 OQS02058.1 - 0.00047 19.8 11.9 0.0018 18.0 2.1 3.1 1 1 2 3 3 3 2 TPR repeat TPR_16 PF13432.6 OQS02058.1 - 0.0005 20.7 1.0 0.0005 20.7 1.0 2.9 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 OQS02058.1 - 0.0015 19.2 2.9 5 8.2 0.1 3.5 2 2 1 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 OQS02058.1 - 0.0016 18.7 11.0 0.0064 16.8 1.4 3.1 2 1 2 4 4 4 3 Tetratricopeptide repeat TPR_19 PF14559.6 OQS02058.1 - 0.0028 18.1 8.0 0.43 11.1 2.3 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat HemY_N PF07219.13 OQS02058.1 - 0.41 10.9 10.1 0.53 10.5 4.1 2.6 1 1 2 3 3 3 0 HemY protein N-terminus TPR_6 PF13174.6 OQS02058.1 - 0.48 11.2 12.2 48 4.9 0.8 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_10 PF13374.6 OQS02058.1 - 0.53 10.2 7.1 3.4 7.7 0.5 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF775 PF05603.12 OQS02059.1 - 4.8e-41 140.5 0.7 2.9e-39 134.7 0.7 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF775) RhoGAP PF00620.27 OQS02060.1 - 0.00056 19.8 1.9 0.00056 19.8 1.9 2.5 2 1 1 3 3 3 1 RhoGAP domain B56 PF01603.20 OQS02061.1 - 2.7e-165 550.4 1.9 3.2e-165 550.1 1.9 1.0 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) Uma2 PF05685.12 OQS02063.1 - 1.8e-08 34.1 0.0 2.7e-08 33.5 0.0 1.2 1 0 0 1 1 1 1 Putative restriction endonuclease Pkinase PF00069.25 OQS02064.1 - 1.6e-11 44.1 0.5 3.5e-09 36.4 0.5 2.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQS02064.1 - 1e-06 28.3 0.2 5.9e-06 25.8 0.2 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_Tyr PF07714.17 OQS02065.1 - 1.2e-06 28.0 0.0 3.2e-06 26.6 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.25 OQS02065.1 - 0.00092 18.6 0.0 0.0019 17.6 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain UAA PF08449.11 OQS02066.1 - 1.8e-26 93.1 6.3 2.2e-26 92.8 6.3 1.1 1 0 0 1 1 1 1 UAA transporter family CRT-like PF08627.10 OQS02066.1 - 2.6e-06 26.7 1.7 3.4e-06 26.3 1.7 1.1 1 0 0 1 1 1 1 CRT-like, chloroquine-resistance transporter-like EamA PF00892.20 OQS02066.1 - 4e-05 23.8 10.0 0.0047 17.1 7.5 2.4 2 1 0 2 2 2 2 EamA-like transporter family TPT PF03151.16 OQS02066.1 - 0.0011 18.4 1.0 0.0018 17.7 1.0 1.3 1 1 0 1 1 1 1 Triose-phosphate Transporter family MtrE PF04206.12 OQS02066.1 - 0.012 15.0 0.6 0.021 14.1 0.6 1.3 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, subunit E DUF2474 PF10617.9 OQS02066.1 - 0.13 12.2 0.5 0.33 10.8 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2474) SLAC1 PF03595.17 OQS02066.1 - 0.33 10.2 7.8 0.16 11.2 4.6 1.8 1 1 1 2 2 2 0 Voltage-dependent anion channel AAA_lid_9 PF17871.1 OQS02067.1 - 1.4e-34 118.2 3.4 1.6e-34 118.0 0.9 2.4 1 1 1 2 2 2 1 AAA lid domain Clp_N PF02861.20 OQS02067.1 - 1.8e-15 56.8 0.3 8.3e-07 29.0 0.0 3.0 2 0 0 2 2 2 2 Clp amino terminal domain, pathogenicity island component AAA PF00004.29 OQS02067.1 - 1.2e-13 51.7 0.0 3e-13 50.3 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 OQS02067.1 - 1.9e-08 34.9 4.8 1.9e-06 28.3 0.0 3.8 3 1 1 4 4 4 1 AAA ATPase domain AAA_22 PF13401.6 OQS02067.1 - 5.9e-05 23.4 0.3 0.019 15.2 0.0 3.5 1 1 1 2 2 2 1 AAA domain TniB PF05621.11 OQS02067.1 - 9.8e-05 21.8 1.2 0.011 15.1 0.0 2.7 2 1 0 2 2 2 1 Bacterial TniB protein AAA_5 PF07728.14 OQS02067.1 - 0.0001 22.3 1.1 0.0034 17.4 0.0 2.9 2 2 1 3 3 3 1 AAA domain (dynein-related subfamily) AAA_25 PF13481.6 OQS02067.1 - 0.0002 21.0 0.1 0.0053 16.3 0.0 2.8 2 1 0 2 2 2 1 AAA domain ATPase_2 PF01637.18 OQS02067.1 - 0.00036 20.5 2.8 0.56 10.1 0.1 3.1 3 0 0 3 3 3 2 ATPase domain predominantly from Archaea IstB_IS21 PF01695.17 OQS02067.1 - 0.011 15.5 0.0 0.023 14.4 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_14 PF13173.6 OQS02067.1 - 0.042 13.9 0.0 0.13 12.3 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 OQS02067.1 - 0.054 14.0 0.0 1.7 9.2 0.0 2.8 2 1 0 2 2 2 0 AAA domain NACHT PF05729.12 OQS02067.1 - 0.072 13.0 0.0 0.24 11.3 0.0 1.9 1 0 0 1 1 1 0 NACHT domain AAA_28 PF13521.6 OQS02067.1 - 0.086 13.1 0.5 2.7 8.2 0.0 3.0 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.6 OQS02067.1 - 0.14 12.5 0.8 0.64 10.3 0.8 2.4 1 1 0 1 1 1 0 AAA domain AAA_7 PF12775.7 OQS02067.1 - 0.15 11.6 0.0 0.37 10.3 0.0 1.7 1 1 0 1 1 1 0 P-loop containing dynein motor region FYVE PF01363.21 OQS02068.1 - 3.1e-09 36.8 12.7 6.7e-09 35.8 12.7 1.6 1 0 0 1 1 1 1 FYVE zinc finger Fea1 PF07692.11 OQS02068.1 - 0.082 11.9 0.1 0.14 11.2 0.1 1.2 1 0 0 1 1 1 0 Low iron-inducible periplasmic protein FYVE_2 PF02318.16 OQS02068.1 - 0.13 12.4 8.4 0.32 11.2 8.4 1.6 1 0 0 1 1 1 0 FYVE-type zinc finger DZR PF12773.7 OQS02068.1 - 1 9.4 13.5 17 5.5 13.5 2.6 1 1 0 1 1 1 0 Double zinc ribbon Mito_carr PF00153.27 OQS02069.1 - 8.7e-59 195.5 0.5 7.7e-19 67.4 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Nop16 PF09420.10 OQS02070.1 - 2.6e-25 89.7 8.6 2.6e-16 60.3 0.9 2.0 1 1 1 2 2 2 2 Ribosome biogenesis protein Nop16 zf-C3HC4_3 PF13920.6 OQS02071.1 - 1.5e-11 43.9 13.0 2.8e-11 43.1 13.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 OQS02071.1 - 1.4e-05 24.9 15.5 2.8e-05 23.9 15.5 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 OQS02071.1 - 8.6e-05 22.4 15.2 0.0002 21.2 15.2 1.7 1 0 0 1 1 1 1 zinc-RING finger domain Tudor-knot PF11717.8 OQS02071.1 - 0.00044 20.1 0.1 0.0011 18.8 0.1 1.7 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain zf-RING_2 PF13639.6 OQS02071.1 - 0.00062 20.0 15.8 0.00062 20.0 15.8 1.9 2 0 0 2 2 1 1 Ring finger domain zf-C3HC4 PF00097.25 OQS02071.1 - 0.0013 18.6 15.8 0.0013 18.6 15.8 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OQS02071.1 - 0.0035 17.3 9.7 0.0035 17.3 9.7 3.4 3 0 0 3 3 3 1 RING-type zinc-finger UPF0242 PF06785.11 OQS02071.1 - 0.011 15.9 1.9 0.013 15.6 1.9 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus zf-C3HC4_2 PF13923.6 OQS02071.1 - 0.033 14.0 18.5 0.039 13.8 16.5 2.1 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Herpes_BLRF2 PF05812.12 OQS02071.1 - 0.07 13.3 0.5 0.1 12.8 0.5 1.3 1 0 0 1 1 1 0 Herpesvirus BLRF2 protein DUF2039 PF10217.9 OQS02071.1 - 0.084 13.2 6.8 0.14 12.5 6.8 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2039) DUF4164 PF13747.6 OQS02071.1 - 0.085 13.2 2.9 0.25 11.6 2.7 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4164) SMN PF06003.12 OQS02071.1 - 0.085 12.1 0.0 0.11 11.8 0.0 1.0 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) Csm1_N PF18504.1 OQS02071.1 - 0.086 13.2 3.2 0.16 12.3 3.2 1.4 1 0 0 1 1 1 0 Csm1 N-terminal domain Fungal_TACC PF12709.7 OQS02071.1 - 0.11 13.0 3.5 1.9 9.0 0.3 2.2 1 1 1 2 2 2 0 Fungal Transforming acidic coiled-coil (TACC) proteins zf-C3HC4_4 PF15227.6 OQS02071.1 - 0.15 12.3 12.9 2.1 8.6 12.9 2.5 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING ZapB PF06005.12 OQS02071.1 - 0.18 12.2 5.4 0.32 11.5 5.4 1.4 1 0 0 1 1 1 0 Cell division protein ZapB IFP_35_N PF07334.13 OQS02071.1 - 0.45 10.6 3.9 0.36 10.9 2.4 1.6 1 1 0 1 1 1 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus TBCA PF02970.16 OQS02071.1 - 0.47 10.8 5.7 0.83 10.0 5.7 1.4 1 1 0 1 1 1 0 Tubulin binding cofactor A zf-RING_4 PF14570.6 OQS02071.1 - 1.4 8.8 8.7 4 7.3 8.7 1.9 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain Malate_synthase PF01274.22 OQS02073.1 - 4.4e-206 685.2 0.0 4.9e-206 685.0 0.0 1.0 1 0 0 1 1 1 1 Malate synthase HpcH_HpaI PF03328.14 OQS02073.1 - 0.02 14.1 0.0 0.035 13.2 0.0 1.4 1 0 0 1 1 1 0 HpcH/HpaI aldolase/citrate lyase family LNS2 PF08235.13 OQS02075.1 - 1.2e-47 162.3 0.0 1.9e-47 161.6 0.0 1.2 1 0 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) Lipin_N PF04571.14 OQS02075.1 - 7.6e-10 38.7 0.0 1.7e-09 37.5 0.0 1.5 1 0 0 1 1 1 1 lipin, N-terminal conserved region Peptidase_M1_N PF17900.1 OQS02076.1 - 0.18 11.9 0.0 0.21 11.7 0.0 1.1 1 0 0 1 1 1 0 Peptidase M1 N-terminal domain Anoctamin PF04547.12 OQS02077.1 - 8.4e-106 354.5 8.3 1.1e-105 354.1 8.3 1.2 1 0 0 1 1 1 1 Calcium-activated chloride channel LrgB PF04172.16 OQS02077.1 - 0.57 9.7 5.8 2.7 7.5 0.5 2.5 2 0 0 2 2 2 0 LrgB-like family HHH_3 PF12836.7 OQS02078.1 - 4.4e-05 23.7 0.0 6e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 Helix-hairpin-helix motif Paired_CXXCH_1 PF09699.10 OQS02079.1 - 0.44 10.3 0.1 0.44 10.3 0.1 2.9 4 0 0 4 4 4 0 Doubled CXXCH motif (Paired_CXXCH_1) DZR PF12773.7 OQS02079.1 - 2.1 8.4 15.3 71 3.5 15.3 2.3 1 1 0 1 1 1 0 Double zinc ribbon CTD_bind PF04818.13 OQS02080.1 - 9.6e-09 35.9 0.0 2.4e-08 34.7 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase II-binding domain. CREPT PF16566.5 OQS02080.1 - 0.0031 17.7 1.3 0.074 13.2 0.1 2.8 2 0 0 2 2 2 1 Cell-cycle alteration and expression-elevated protein in tumour DUF3755 PF12579.8 OQS02080.1 - 0.18 11.4 5.2 0.22 11.2 3.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3755) SF3A3 PF16837.5 OQS02081.1 - 0.023 15.2 1.0 2.7 8.6 0.0 2.4 2 0 0 2 2 2 0 Pre-mRNA-splicing factor SF3A3, of SF3a complex, Prp9 DUF1116 PF06545.11 OQS02081.1 - 0.052 13.0 0.0 0.076 12.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1116) TPR_2 PF07719.17 OQS02081.1 - 1.8 8.9 5.0 1.8 8.9 0.2 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat Lipase_3 PF01764.25 OQS02082.1 - 9.9e-10 38.4 0.0 2.2e-09 37.3 0.0 1.6 1 0 0 1 1 1 1 Lipase (class 3) Hydrolase_4 PF12146.8 OQS02082.1 - 0.048 12.9 0.0 0.12 11.7 0.0 1.6 1 0 0 1 1 1 0 Serine aminopeptidase, S33 DUF1072 PF06380.11 OQS02082.1 - 0.07 13.0 0.0 0.17 11.8 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1072) DnaJ PF00226.31 OQS02083.1 - 2.1e-21 75.8 0.1 9.2e-21 73.7 0.1 2.2 1 0 0 1 1 1 1 DnaJ domain zf-C2H2_jaz PF12171.8 OQS02083.1 - 2.5e-09 37.2 4.5 7e-09 35.7 4.5 1.8 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 OQS02083.1 - 2.4e-08 34.1 3.1 2.4e-08 34.1 3.1 2.3 3 0 0 3 3 3 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 OQS02083.1 - 5.8e-05 23.4 1.2 0.00023 21.4 1.2 2.1 1 0 0 1 1 1 1 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.6 OQS02083.1 - 0.00024 21.7 2.7 0.012 16.4 0.3 2.8 2 0 0 2 2 2 1 C2H2-type zinc finger zf-DBF PF07535.12 OQS02083.1 - 0.00048 20.2 0.3 0.00048 20.2 0.3 2.2 2 0 0 2 2 2 1 DBF zinc finger zf-C2H2 PF00096.26 OQS02083.1 - 0.001 19.4 3.6 0.056 13.9 0.6 2.7 2 0 0 2 2 2 1 Zinc finger, C2H2 type zf-C2H2_6 PF13912.6 OQS02083.1 - 0.0089 16.0 5.1 0.25 11.4 2.2 2.8 2 0 0 2 2 2 1 C2H2-type zinc finger zf-MYST PF17772.1 OQS02083.1 - 0.12 12.0 0.2 0.24 11.1 0.2 1.5 1 0 0 1 1 1 0 MYST family zinc finger domain EMC3_TMCO1 PF01956.16 OQS02083.1 - 0.27 11.0 12.5 0.087 12.6 0.6 2.6 2 1 0 2 2 2 0 Integral membrane protein EMC3/TMCO1-like DUF123 PF01986.16 OQS02083.1 - 3 8.4 5.6 49 4.5 2.6 3.2 2 1 0 2 2 2 0 Domain of unknown function DUF123 AKAP95 PF04988.12 OQS02083.1 - 5.2 7.3 21.6 0.029 14.6 6.0 3.2 2 1 1 3 3 3 0 A-kinase anchoring protein 95 (AKAP95) RRM_1 PF00076.22 OQS02084.1 - 3.7e-18 65.1 0.0 5.2e-18 64.6 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 OQS02084.1 - 0.0014 18.5 0.0 0.0024 17.7 0.0 1.3 1 0 0 1 1 1 1 Occluded RNA-recognition motif RRM_5 PF13893.6 OQS02084.1 - 0.0015 18.1 0.0 0.0021 17.7 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PRE_C2HC PF07530.11 OQS02084.1 - 0.0048 17.0 0.0 0.026 14.6 0.0 2.3 1 1 1 2 2 2 1 Associated with zinc fingers SseB_C PF14581.6 OQS02084.1 - 0.008 16.3 0.0 0.012 15.7 0.0 1.2 1 0 0 1 1 1 1 SseB protein C-terminal domain RRM_3 PF08777.11 OQS02084.1 - 0.045 13.8 0.2 0.074 13.1 0.2 1.5 1 1 0 1 1 1 0 RNA binding motif OB_RNB PF08206.11 OQS02084.1 - 0.085 12.5 0.2 0.55 10.0 0.1 2.5 2 0 0 2 2 2 0 Ribonuclease B OB domain RL PF17797.1 OQS02084.1 - 0.14 12.1 0.0 0.26 11.3 0.0 1.4 1 0 0 1 1 1 0 RL domain Aa_trans PF01490.18 OQS02085.1 - 1.7e-20 73.1 28.8 3.3e-14 52.4 18.1 2.1 2 0 0 2 2 2 2 Transmembrane amino acid transporter protein ArfGap PF01412.18 OQS02086.1 - 1.4e-29 102.5 0.2 2.8e-29 101.6 0.2 1.4 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf PDZ_6 PF17820.1 OQS02086.1 - 2.3e-08 33.8 1.2 4.7e-05 23.1 0.2 2.4 2 0 0 2 2 2 2 PDZ domain PDZ PF00595.24 OQS02086.1 - 3.9e-07 30.3 0.5 0.013 15.8 0.0 2.2 2 0 0 2 2 2 2 PDZ domain PDZ_2 PF13180.6 OQS02086.1 - 2.3e-05 24.6 0.4 0.26 11.6 0.0 2.2 2 0 0 2 2 2 2 PDZ domain zf-C2H2 PF00096.26 OQS02086.1 - 0.58 10.7 0.1 0.58 10.7 0.1 1.9 2 0 0 2 2 2 0 Zinc finger, C2H2 type PNK3P PF08645.11 OQS02087.1 - 1.1e-51 174.7 0.1 3e-51 173.4 0.1 1.7 2 0 0 2 2 2 1 Polynucleotide kinase 3 phosphatase AAA_33 PF13671.6 OQS02087.1 - 1.7e-13 50.9 0.0 3.2e-07 30.6 0.0 2.4 1 1 1 2 2 2 2 AAA domain BRCT_2 PF16589.5 OQS02087.1 - 1.4e-05 25.4 0.0 5.3e-05 23.6 0.0 2.0 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain Zeta_toxin PF06414.12 OQS02087.1 - 0.0023 17.2 0.1 0.8 8.9 0.0 2.7 2 1 0 3 3 3 2 Zeta toxin AAA_22 PF13401.6 OQS02087.1 - 0.019 15.3 0.0 0.037 14.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain KTI12 PF08433.10 OQS02087.1 - 0.035 13.5 0.3 6.4 6.1 0.1 2.2 1 1 1 2 2 2 0 Chromatin associated protein KTI12 BRCT_3 PF18428.1 OQS02087.1 - 0.066 13.3 0.0 0.17 12.0 0.0 1.7 1 0 0 1 1 1 0 BRCA1 C Terminus (BRCT) domain Roc PF08477.13 OQS02087.1 - 0.11 12.7 0.1 0.75 10.0 0.0 2.3 2 1 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase 6PF2K PF01591.18 OQS02087.1 - 0.11 11.7 0.1 0.72 9.1 0.0 1.9 1 1 1 2 2 2 0 6-phosphofructo-2-kinase Ploopntkinase3 PF18751.1 OQS02087.1 - 0.13 12.2 0.0 0.22 11.4 0.0 1.3 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 TsaE PF02367.17 OQS02087.1 - 0.14 12.2 0.0 2 8.4 0.0 2.6 3 0 0 3 3 3 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_16 PF13191.6 OQS02087.1 - 0.17 12.3 0.0 0.34 11.3 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain RSN1_7TM PF02714.15 OQS02088.1 - 4e-48 164.1 26.8 7.2e-48 163.3 26.8 1.4 1 0 0 1 1 1 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 OQS02088.1 - 3.4e-26 91.9 4.7 4.1e-26 91.6 1.5 2.8 2 0 0 2 2 2 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 OQS02088.1 - 1.8e-20 73.9 8.0 1.6e-15 57.8 0.8 2.2 1 1 0 2 2 2 2 Cytosolic domain of 10TM putative phosphate transporter ADK PF00406.22 OQS02088.1 - 0.054 13.6 0.2 0.099 12.7 0.2 1.3 1 0 0 1 1 1 0 Adenylate kinase NDUF_B8 PF05821.11 OQS02088.1 - 0.082 12.8 0.0 0.24 11.2 0.0 1.8 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase ASHI subunit (CI-ASHI or NDUFB8) IML1 PF12257.8 OQS02089.1 - 5.2e-77 258.8 0.0 1.1e-76 257.7 0.0 1.6 1 0 0 1 1 1 1 Vacuolar membrane-associated protein Iml1 FYVE PF01363.21 OQS02089.1 - 3.1e-07 30.4 14.2 7.9e-07 29.1 14.2 1.7 1 0 0 1 1 1 1 FYVE zinc finger EF-hand_7 PF13499.6 OQS02090.1 - 4.1e-05 23.9 0.0 0.00012 22.5 0.0 1.8 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 OQS02090.1 - 0.00016 21.3 0.2 0.036 14.0 0.0 3.0 2 1 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.32 OQS02090.1 - 0.1 12.2 0.1 3.3 7.5 0.0 2.6 2 0 0 2 2 2 0 EF hand Hydrolase_6 PF13344.6 OQS02091.1 - 1.7e-25 89.0 0.0 3e-25 88.2 0.0 1.4 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 OQS02091.1 - 2.1e-19 69.4 0.0 6e-19 67.9 0.0 1.8 2 0 0 2 2 2 1 HAD-hyrolase-like Hydrolase PF00702.26 OQS02091.1 - 1.8e-10 41.5 0.0 4.1e-05 24.0 0.0 2.1 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 OQS02091.1 - 1e-06 28.9 0.0 0.0034 17.5 0.0 2.2 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Acid_phosphat_B PF03767.14 OQS02091.1 - 0.00088 18.9 0.0 0.0012 18.5 0.0 1.2 1 0 0 1 1 1 1 HAD superfamily, subfamily IIIB (Acid phosphatase) Glyco_hydro_30C PF17189.4 OQS02091.1 - 0.071 13.3 0.1 0.18 12.1 0.1 1.7 1 0 0 1 1 1 0 Glycosyl hydrolase family 30 beta sandwich domain ADH_zinc_N PF00107.26 OQS02091.1 - 0.16 11.9 2.4 0.15 12.1 0.4 1.8 2 0 0 2 2 2 0 Zinc-binding dehydrogenase DUF596 PF04591.12 OQS02092.1 - 0.0084 16.2 0.1 0.015 15.4 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF596 Ubiquitin_4 PF18036.1 OQS02092.1 - 0.11 12.5 0.0 0.2 11.7 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin-like domain Astro_capsid_p PF12226.8 OQS02093.1 - 0.0073 15.5 0.3 0.0087 15.3 0.3 1.2 1 0 0 1 1 1 1 Turkey astrovirus capsid protein IL1 PF00340.19 OQS02093.1 - 0.0079 15.8 0.6 0.021 14.5 0.6 1.7 1 0 0 1 1 1 1 Interleukin-1 / 18 ISAV_HA PF06215.11 OQS02093.1 - 0.052 12.7 0.1 0.082 12.0 0.1 1.3 1 0 0 1 1 1 0 Infectious salmon anaemia virus haemagglutinin CobT PF06213.12 OQS02093.1 - 1.7 8.0 9.4 2.4 7.4 9.4 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Cwf_Cwc_15 PF04889.12 OQS02093.1 - 2.4 7.8 11.3 3.5 7.3 11.3 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DUF2722 PF10846.8 OQS02093.1 - 3.1 6.6 7.6 4.5 6.1 7.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) TRAP_alpha PF03896.16 OQS02093.1 - 3.3 6.8 5.8 4.9 6.3 5.8 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit DUF2457 PF10446.9 OQS02093.1 - 4.2 6.4 13.9 5.9 5.9 13.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) CDC45 PF02724.14 OQS02093.1 - 5 5.3 9.6 7.9 4.6 9.6 1.2 1 0 0 1 1 1 0 CDC45-like protein BUD22 PF09073.10 OQS02093.1 - 6.8 5.9 10.9 9.6 5.4 10.9 1.1 1 0 0 1 1 1 0 BUD22 Nucleoside_tran PF01733.18 OQS02094.1 - 1.3e-05 24.8 5.6 1.3e-05 24.8 5.6 1.9 2 1 0 2 2 2 1 Nucleoside transporter DUF1011 PF06237.12 OQS02094.1 - 3e-05 24.2 2.7 3e-05 24.2 2.7 3.4 4 0 0 4 4 4 1 Protein of unknown function (DUF1011) WD40 PF00400.32 OQS02095.1 - 1.2e-34 117.7 26.9 1.4e-06 28.9 0.6 7.1 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OQS02095.1 - 1.1e-11 44.8 0.2 0.21 11.9 0.0 5.3 1 1 4 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 OQS02095.1 - 0.0021 17.4 0.1 0.77 9.0 0.0 2.9 1 1 2 3 3 3 2 WD40-like domain Ge1_WD40 PF16529.5 OQS02095.1 - 0.057 12.4 0.1 7.1 5.5 0.0 3.3 2 1 1 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein PKD_channel PF08016.12 OQS02096.1 - 1.8e-63 214.7 23.9 1.5e-62 211.7 23.9 2.1 1 1 0 1 1 1 1 Polycystin cation channel Ion_trans PF00520.31 OQS02096.1 - 2.7e-18 66.1 20.0 5.8e-18 65.0 20.0 1.6 1 0 0 1 1 1 1 Ion transport protein TIL PF01826.17 OQS02096.1 - 0.74 10.1 6.5 1.4 9.2 6.5 1.4 1 0 0 1 1 1 0 Trypsin Inhibitor like cysteine rich domain PARP PF00644.20 OQS02098.1 - 1.3e-35 122.8 0.0 1.8e-35 122.3 0.0 1.2 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain PhoLip_ATPase_C PF16212.5 OQS02099.1 - 6.9e-135 448.5 56.7 2.5e-74 250.2 24.3 4.3 5 0 0 5 5 5 2 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 OQS02099.1 - 1.1e-40 137.1 17.7 2e-22 78.6 0.3 3.3 3 0 0 3 3 3 2 Phospholipid-translocating ATPase N-terminal Cation_ATPase PF13246.6 OQS02099.1 - 3.8e-23 81.4 0.0 8e-10 38.7 0.0 4.2 4 0 0 4 4 4 2 Cation transport ATPase (P-type) Hydrolase PF00702.26 OQS02099.1 - 1.5e-21 77.6 0.8 0.00018 21.9 0.0 5.5 3 2 0 4 4 4 4 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 OQS02099.1 - 1.3e-15 57.4 4.1 6.2e-07 29.1 0.0 3.3 3 0 0 3 3 3 2 E1-E2 ATPase Hydrolase_3 PF08282.12 OQS02099.1 - 1.1e-10 41.7 0.2 0.001 18.9 0.0 3.2 3 0 0 3 3 3 2 haloacid dehalogenase-like hydrolase HAD PF12710.7 OQS02099.1 - 0.0023 18.4 0.3 4.2 7.7 0.0 4.5 4 1 1 5 5 5 1 haloacid dehalogenase-like hydrolase Ribosomal_S16 PF00886.19 OQS02101.1 - 7.3e-26 90.0 0.1 9.5e-26 89.6 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein S16 PPR_2 PF13041.6 OQS02102.1 - 7.7e-42 141.3 12.9 5.1e-10 39.4 0.2 8.6 2 2 7 9 9 9 8 PPR repeat family PPR_3 PF13812.6 OQS02102.1 - 3.1e-38 129.7 3.5 1.1e-10 41.4 0.0 6.2 4 2 2 6 6 6 6 Pentatricopeptide repeat domain PPR PF01535.20 OQS02102.1 - 2.9e-32 108.6 19.1 7e-07 29.1 0.0 10.3 9 1 0 9 9 9 7 PPR repeat PPR_1 PF12854.7 OQS02102.1 - 5.8e-31 105.9 1.6 1.6e-09 37.3 0.0 8.3 9 0 0 9 9 9 6 PPR repeat UPF0020 PF01170.18 OQS02102.1 - 4.1e-23 82.1 0.0 1.2e-21 77.4 0.0 3.2 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 PPR_long PF17177.4 OQS02102.1 - 1.1e-22 80.5 1.7 9.1e-14 51.3 0.0 4.5 4 1 2 6 6 5 2 Pentacotripeptide-repeat region of PRORP Rep_fac_C PF08542.11 OQS02102.1 - 3.2e-21 75.5 0.0 1.7e-20 73.2 0.0 2.4 1 0 0 1 1 1 1 Replication factor C C-terminal domain AAA PF00004.29 OQS02102.1 - 2.5e-12 47.3 0.1 6.9e-12 45.9 0.1 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.6 OQS02102.1 - 3.2e-11 43.3 0.7 2.1e-09 37.4 0.6 2.8 2 1 1 3 3 3 1 DNA polymerase III, delta subunit AAA_14 PF13173.6 OQS02102.1 - 4.1e-06 26.9 0.0 1.3e-05 25.3 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 OQS02102.1 - 3.4e-05 24.3 0.0 0.00094 19.6 0.0 2.6 1 1 1 2 2 2 1 AAA ATPase domain MTS PF05175.14 OQS02102.1 - 7.7e-05 22.3 0.0 0.00018 21.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase small domain THUMP PF02926.17 OQS02102.1 - 0.00015 21.9 0.0 0.00047 20.3 0.0 1.8 1 1 0 1 1 1 1 THUMP domain RuvB_N PF05496.12 OQS02102.1 - 0.00021 21.0 0.0 0.00053 19.8 0.0 1.7 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_24 PF13479.6 OQS02102.1 - 0.00063 19.5 0.1 0.0016 18.2 0.0 1.7 2 0 0 2 2 1 1 AAA domain Rad17 PF03215.15 OQS02102.1 - 0.00074 19.5 0.0 0.0017 18.3 0.0 1.5 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_22 PF13401.6 OQS02102.1 - 0.0016 18.8 0.1 0.3 11.3 0.0 2.6 1 1 1 2 2 2 1 AAA domain Methyltransf_11 PF08241.12 OQS02102.1 - 0.0026 18.4 0.0 0.014 16.1 0.0 2.4 1 0 0 1 1 1 1 Methyltransferase domain Viral_helicase1 PF01443.18 OQS02102.1 - 0.0026 17.5 0.0 0.0062 16.3 0.0 1.6 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase Methyltransf_25 PF13649.6 OQS02102.1 - 0.0041 17.8 0.0 0.032 14.9 0.0 2.6 2 0 0 2 2 2 1 Methyltransferase domain TPR_14 PF13428.6 OQS02102.1 - 0.016 15.9 3.2 11 7.1 0.0 5.7 5 1 0 5 5 4 0 Tetratricopeptide repeat AAA_19 PF13245.6 OQS02102.1 - 0.017 15.4 0.0 0.081 13.3 0.0 2.2 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 OQS02102.1 - 0.018 14.6 0.0 0.27 10.8 0.0 2.6 2 0 0 2 2 2 0 AAA domain Mg_chelatase PF01078.21 OQS02102.1 - 0.02 14.3 0.0 0.15 11.4 0.0 2.2 1 1 0 2 2 2 0 Magnesium chelatase, subunit ChlI Helicase_RecD PF05127.14 OQS02102.1 - 0.022 14.6 0.8 9.4 6.0 0.0 2.9 3 0 0 3 3 2 0 Helicase AAA_11 PF13086.6 OQS02102.1 - 0.025 14.4 0.5 0.069 12.9 0.0 1.9 2 0 0 2 2 1 0 AAA domain AAA_3 PF07726.11 OQS02102.1 - 0.031 14.1 0.1 0.08 12.8 0.1 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ATP13 PF12921.7 OQS02102.1 - 0.031 14.1 0.1 13 5.6 0.0 4.0 4 1 1 5 5 5 0 Mitochondrial ATPase expression NTPase_1 PF03266.15 OQS02102.1 - 0.045 13.7 0.5 0.55 10.1 0.0 2.7 3 0 0 3 3 3 0 NTPase AviRa PF11599.8 OQS02102.1 - 0.083 12.3 0.2 0.57 9.6 0.0 2.3 2 1 1 3 3 3 0 RRNA methyltransferase AviRa RNA_helicase PF00910.22 OQS02102.1 - 0.098 13.1 0.0 0.37 11.2 0.0 2.1 1 0 0 1 1 1 0 RNA helicase mRNA_stabil PF13929.6 OQS02102.1 - 0.11 11.5 0.0 0.22 10.5 0.0 1.5 1 0 0 1 1 1 0 mRNA stabilisation Ubie_methyltran PF01209.18 OQS02102.1 - 0.13 11.6 0.0 0.37 10.1 0.0 1.7 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family ALMS_motif PF15309.6 OQS02103.1 - 0.00062 20.2 19.6 0.00062 20.2 19.6 5.5 3 1 0 4 4 4 1 ALMS motif Motile_Sperm PF00635.26 OQS02104.1 - 5.6e-09 35.8 0.1 1.6e-08 34.3 0.1 1.8 1 0 0 1 1 1 1 MSP (Major sperm protein) domain TPPII PF12580.8 OQS02104.1 - 0.072 12.6 0.1 0.15 11.5 0.1 1.5 1 0 0 1 1 1 0 Tripeptidyl peptidase II Aph-1 PF06105.12 OQS02105.1 - 3.5e-46 157.5 19.1 4e-46 157.3 19.1 1.0 1 0 0 1 1 1 1 Aph-1 protein DUF382 PF04037.13 OQS02106.1 - 7.4e-52 174.8 1.3 2.2e-50 170.1 0.0 2.6 2 0 0 2 2 2 1 Domain of unknown function (DUF382) PSP PF04046.16 OQS02106.1 - 2.6e-19 68.8 2.3 6.4e-19 67.6 2.3 1.7 1 0 0 1 1 1 1 PSP DNA_pol3_beta_3 PF02768.15 OQS02106.1 - 0.12 12.2 0.7 0.31 10.9 0.7 1.6 1 0 0 1 1 1 0 DNA polymerase III beta subunit, C-terminal domain NAGLU PF05089.12 OQS02108.1 - 1.2e-122 409.1 7.5 2e-122 408.3 7.5 1.4 1 0 0 1 1 1 1 Alpha-N-acetylglucosaminidase (NAGLU) tim-barrel domain NAGLU_C PF12972.7 OQS02108.1 - 2.1e-66 224.2 5.1 3.3e-66 223.5 5.1 1.3 1 0 0 1 1 1 1 Alpha-N-acetylglucosaminidase (NAGLU) C-terminal domain NAGLU_N PF12971.7 OQS02108.1 - 9.3e-13 47.8 0.1 3.5e-12 45.9 0.0 2.1 2 0 0 2 2 2 1 Alpha-N-acetylglucosaminidase (NAGLU) N-terminal domain Ribosomal_L7Ae PF01248.26 OQS02109.1 - 5.9e-23 80.4 1.3 1.2e-22 79.5 1.3 1.4 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.11 OQS02109.1 - 0.0093 16.0 0.3 0.15 12.1 0.3 2.2 1 1 0 1 1 1 1 RNase P subunit Pop3 AMPK1_CBM PF16561.5 OQS02109.1 - 0.078 13.2 0.0 0.15 12.3 0.0 1.4 1 0 0 1 1 1 0 Glycogen recognition site of AMP-activated protein kinase Ank_5 PF13857.6 OQS02110.1 - 8.8e-32 108.8 12.5 6.7e-05 23.1 0.0 10.0 1 1 9 11 11 11 8 Ankyrin repeats (many copies) Ank_2 PF12796.7 OQS02110.1 - 9.7e-32 109.4 12.1 1.3e-08 35.3 0.4 4.7 1 1 5 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQS02110.1 - 7e-27 93.5 8.4 3.7e-05 24.2 0.1 6.7 4 2 4 8 8 8 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQS02110.1 - 8e-24 81.1 0.9 0.84 10.4 0.0 10.5 9 1 1 10 10 10 6 Ankyrin repeat DUF5049 PF16468.5 OQS02110.1 - 3e-07 30.2 1.0 3.9 7.5 0.0 7.1 4 2 4 8 8 8 1 Domain of unknown function (DUF5049) Ank PF00023.30 OQS02110.1 - 7.8e-06 26.1 0.1 13 6.5 0.0 6.2 3 1 0 3 3 3 1 Ankyrin repeat Helicase_PWI PF18149.1 OQS02110.1 - 0.0006 20.0 0.0 17 5.7 0.0 4.5 3 1 1 4 4 4 0 N-terminal helicase PWI domain CNOT1_HEAT PF16418.5 OQS02110.1 - 0.0071 16.4 0.4 7.2 6.7 0.0 4.5 6 0 0 6 6 6 1 CCR4-NOT transcription complex subunit 1 HEAT repeat DUF4411 PF14367.6 OQS02110.1 - 0.033 14.1 0.1 3.2 7.6 0.0 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4411) DUF1987 PF09345.10 OQS02110.1 - 0.063 13.0 3.0 13 5.5 0.0 3.7 4 0 0 4 4 4 0 Domain of unknown function (DUF1987) Reovirus_L2 PF06016.11 OQS02110.1 - 0.2 8.8 0.0 0.25 8.5 0.0 1.0 1 0 0 1 1 1 0 Reovirus core-spike protein lambda-2 (L2) Glyco_trans_4_5 PF16994.5 OQS02110.1 - 0.69 9.5 5.9 11 5.6 0.2 3.9 2 1 2 4 4 4 0 Glycosyl-transferase family 4 Cse1 PF08506.10 OQS02111.1 - 5.2e-117 390.8 3.8 8.9e-117 390.0 3.8 1.4 1 0 0 1 1 1 1 Cse1 CAS_CSE1 PF03378.15 OQS02111.1 - 2.1e-94 316.5 3.9 3.3e-94 315.9 1.5 2.2 2 0 0 2 2 2 1 CAS/CSE protein, C-terminus IBN_N PF03810.19 OQS02111.1 - 8.3e-10 38.4 0.0 4.7e-09 36.0 0.0 2.4 3 0 0 3 3 3 1 Importin-beta N-terminal domain Xpo1 PF08389.12 OQS02111.1 - 0.041 13.9 4.7 0.063 13.3 0.2 3.4 4 0 0 4 4 4 0 Exportin 1-like protein DUF1586 PF07625.11 OQS02111.1 - 0.12 12.5 0.8 0.37 10.9 0.8 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1586) FPL PF09758.9 OQS02111.1 - 0.31 11.1 3.1 23 5.0 0.0 3.6 3 0 0 3 3 3 0 Uncharacterised conserved protein Cadherin_tail PF15974.5 OQS02112.1 - 0.59 10.5 9.1 4.4 7.6 0.1 2.9 3 0 0 3 3 3 0 Cadherin C-terminal cytoplasmic tail, catenin-binding region Lactamase_B_6 PF16661.5 OQS02113.1 - 2.8e-55 186.8 0.1 5.9e-55 185.7 0.1 1.5 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily domain CPSF100_C PF13299.6 OQS02113.1 - 2.6e-17 63.5 6.8 4.9e-15 56.1 0.1 3.4 3 1 1 4 4 4 2 Cleavage and polyadenylation factor 2 C-terminal Beta-Casp PF10996.8 OQS02113.1 - 1.2e-14 54.5 0.0 2.6e-14 53.5 0.0 1.6 1 0 0 1 1 1 1 Beta-Casp domain RMMBL PF07521.12 OQS02113.1 - 5.8e-11 42.2 0.0 1.5e-10 40.8 0.0 1.7 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain Lactamase_B PF00753.27 OQS02113.1 - 1.7e-06 28.2 0.3 6.6e-06 26.3 0.2 2.0 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 OQS02113.1 - 0.0062 16.1 0.1 0.016 14.7 0.1 1.7 1 0 0 1 1 1 1 Beta-lactamase superfamily domain PAN_3 PF08277.12 OQS02113.1 - 0.054 13.3 1.1 0.31 10.9 0.7 2.3 2 0 0 2 2 2 0 PAN-like domain Fanconi_A_N PF15865.5 OQS02113.1 - 0.078 12.4 0.0 0.12 11.7 0.0 1.2 1 0 0 1 1 1 0 Fanconi anaemia group A protein N terminus SNF2_N PF00176.23 OQS02114.1 - 7.2e-19 67.7 5.1 1.2e-16 60.4 0.7 2.2 1 1 1 2 2 2 2 SNF2 family N-terminal domain Helicase_C PF00271.31 OQS02114.1 - 1.5e-08 35.0 0.6 2.3e-07 31.1 0.0 2.7 3 0 0 3 3 3 1 Helicase conserved C-terminal domain PCI PF01399.27 OQS02115.1 - 3.4e-14 53.2 0.6 1.3e-13 51.4 0.1 2.2 2 0 0 2 2 2 1 PCI domain TetR_C_34 PF17929.1 OQS02115.1 - 0.0055 16.8 0.1 0.027 14.6 0.0 2.1 2 0 0 2 2 2 1 Tetracyclin repressor-like, C-terminal domain CSN4_RPN5_eIF3a PF18420.1 OQS02115.1 - 0.0084 16.3 0.5 0.0084 16.3 0.5 2.1 2 0 0 2 2 2 1 CSN4/RPN5/eIF3a helix turn helix domain TPR_12 PF13424.6 OQS02115.1 - 0.033 14.5 1.7 0.078 13.3 0.4 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.6 OQS02115.1 - 0.22 12.0 3.7 7.4 7.2 0.4 3.1 2 1 1 3 3 3 0 Tetratricopeptide repeat zf-RING_2 PF13639.6 OQS02116.1 - 1.4e-08 34.9 12.5 1.4e-08 34.9 12.5 1.8 2 0 0 2 2 1 1 Ring finger domain zf-rbx1 PF12678.7 OQS02116.1 - 2.3e-08 34.2 9.3 5.4e-08 33.0 9.3 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 OQS02116.1 - 1e-05 25.5 4.5 1e-05 25.5 4.5 2.3 1 1 1 2 2 2 1 RING-type zinc-finger zf-RING_11 PF17123.5 OQS02116.1 - 0.00031 20.4 9.8 0.00031 20.4 9.8 2.5 2 1 0 2 2 2 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 OQS02116.1 - 0.00051 19.8 12.0 0.00051 19.8 12.0 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 OQS02116.1 - 0.0011 18.8 12.7 0.0011 18.8 12.7 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 OQS02116.1 - 0.0025 17.6 11.4 0.0062 16.4 11.4 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 OQS02116.1 - 0.013 15.5 9.7 0.073 13.1 9.8 2.4 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.6 OQS02116.1 - 0.014 15.3 13.7 0.1 12.6 13.9 2.3 1 1 1 2 2 2 0 zinc-RING finger domain Zn_ribbon_17 PF17120.5 OQS02116.1 - 0.052 13.2 10.1 0.15 11.7 10.1 1.8 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type FANCL_C PF11793.8 OQS02116.1 - 0.75 10.0 11.2 3.1 8.0 11.2 2.1 1 1 0 1 1 1 0 FANCL C-terminal domain zf-Nse PF11789.8 OQS02116.1 - 0.78 9.6 5.8 1.7 8.5 5.8 1.6 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4_4 PF15227.6 OQS02116.1 - 1.2 9.3 9.6 4.4 7.5 9.7 2.1 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING adh_short PF00106.25 OQS02117.1 - 1.4e-22 80.1 0.0 4.3e-11 42.6 0.0 2.2 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 OQS02117.1 - 1.6e-19 70.4 0.0 3.9e-12 46.2 0.0 2.2 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OQS02117.1 - 0.00095 19.1 0.0 0.0019 18.1 0.0 1.4 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 OQS02117.1 - 0.0062 16.0 0.0 0.011 15.1 0.0 1.3 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Spt4 PF06093.13 OQS02117.1 - 0.088 12.9 0.1 0.41 10.8 0.0 2.2 3 0 0 3 3 3 0 Spt4/RpoE2 zinc finger Ribonuc_L-PSP PF01042.21 OQS02117.1 - 0.11 12.5 0.0 0.26 11.3 0.0 1.6 1 0 0 1 1 1 0 Endoribonuclease L-PSP Epimerase PF01370.21 OQS02117.1 - 0.11 11.9 0.0 0.19 11.2 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family GATase_6 PF13522.6 OQS02118.1 - 4.4e-15 56.1 0.1 1.3e-14 54.5 0.1 1.8 1 1 1 2 2 2 1 Glutamine amidotransferase domain GATase_7 PF13537.6 OQS02118.1 - 2.4e-14 53.3 0.0 5e-14 52.3 0.0 1.5 2 0 0 2 2 2 1 Glutamine amidotransferase domain GATase_4 PF13230.6 OQS02118.1 - 3.1e-06 26.3 0.0 4.1e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Kelch_4 PF13418.6 OQS02119.1 - 6.5e-42 141.3 3.6 9.1e-12 44.8 0.0 6.3 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_3 PF13415.6 OQS02119.1 - 5.6e-33 112.6 11.6 1.6e-07 31.4 0.1 6.9 6 1 0 6 6 6 5 Galactose oxidase, central domain Kelch_5 PF13854.6 OQS02119.1 - 2e-27 94.7 0.0 0.00016 21.6 0.0 6.3 6 0 0 6 6 6 6 Kelch motif Kelch_6 PF13964.6 OQS02119.1 - 4.7e-26 90.2 4.3 2.4e-05 24.5 0.1 6.1 4 2 2 6 6 6 5 Kelch motif Kelch_1 PF01344.25 OQS02119.1 - 9.3e-25 86.0 2.9 6.6e-09 35.2 0.4 5.9 6 0 0 6 6 6 4 Kelch motif Kelch_2 PF07646.15 OQS02119.1 - 1.7e-22 78.4 3.0 3.7e-06 26.7 0.6 6.1 6 0 0 6 6 6 4 Kelch motif Glyoxal_oxid_N PF07250.11 OQS02119.1 - 0.063 12.5 0.3 1.1 8.3 0.0 2.4 2 0 0 2 2 2 0 Glyoxal oxidase N-terminus Myb_DNA-binding PF00249.31 OQS02120.1 - 2.5e-41 139.6 11.6 4.5e-15 55.6 0.5 3.3 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OQS02120.1 - 4.9e-31 106.8 6.0 4.3e-16 58.9 0.0 3.3 1 1 2 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OQS02120.1 - 1.8e-05 24.6 0.6 5.2e-05 23.1 0.2 1.9 2 0 0 2 2 2 1 Myb DNA-binding like Rap1_C PF11626.8 OQS02120.1 - 0.00063 19.8 2.5 0.86 9.7 0.2 3.3 1 1 2 3 3 3 2 TRF2-interacting telomeric protein/Rap1 - C terminal domain SLIDE PF09111.10 OQS02120.1 - 0.0023 17.9 0.0 0.76 9.8 0.0 3.1 2 1 1 3 3 3 1 SLIDE MADF_DNA_bdg PF10545.9 OQS02120.1 - 0.0055 17.0 7.0 3.2 8.1 0.5 3.3 3 0 0 3 3 3 2 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_4 PF13837.6 OQS02120.1 - 0.15 12.5 10.3 4 7.9 0.8 3.5 3 0 0 3 3 3 0 Myb/SANT-like DNA-binding domain Pkinase_Tyr PF07714.17 OQS02121.1 - 2.5e-40 138.4 0.0 3.4e-40 138.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OQS02121.1 - 2.1e-38 132.2 0.0 3.2e-38 131.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain DEP PF00610.21 OQS02121.1 - 9e-06 25.7 0.0 1.9e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) APH PF01636.23 OQS02121.1 - 0.14 12.0 0.0 0.3 11.0 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family H2O2_YaaD PF03883.14 OQS02122.1 - 6.1e-78 261.5 0.2 7.1e-78 261.3 0.2 1.0 1 0 0 1 1 1 1 Peroxide stress protein YaaA UCH PF00443.29 OQS02123.1 - 1.8e-45 155.4 3.0 3.4e-45 154.6 3.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 OQS02123.1 - 1.7e-22 80.4 6.8 9.8e-22 77.9 6.8 2.0 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase ComR_TPR PF18710.1 OQS02123.1 - 0.084 12.4 0.1 0.2 11.2 0.1 1.6 1 0 0 1 1 1 0 ComR tetratricopeptide Peptidase_S10 PF00450.22 OQS02124.1 - 1.2e-98 331.2 2.1 1.6e-98 330.9 2.1 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase DUF1700 PF08006.11 OQS02124.1 - 0.23 11.0 0.8 0.53 9.8 0.0 1.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1700) Kelch_1 PF01344.25 OQS02125.1 - 5.8e-49 163.4 10.4 4.5e-09 35.8 0.0 6.4 6 0 0 6 6 6 6 Kelch motif Kelch_6 PF13964.6 OQS02125.1 - 2.7e-45 151.2 12.8 1.4e-08 34.7 0.1 6.4 5 1 1 6 6 6 6 Kelch motif Kelch_5 PF13854.6 OQS02125.1 - 6.5e-43 144.1 8.7 2.3e-07 30.6 0.1 6.6 7 0 0 7 7 7 6 Kelch motif Kelch_3 PF13415.6 OQS02125.1 - 5.7e-39 131.7 15.9 6.9e-08 32.6 0.0 7.3 7 0 0 7 7 7 7 Galactose oxidase, central domain Kelch_4 PF13418.6 OQS02125.1 - 2.3e-38 130.0 17.6 4.1e-07 29.9 0.5 6.5 5 1 1 6 6 6 6 Galactose oxidase, central domain Kelch_2 PF07646.15 OQS02125.1 - 4.8e-29 99.2 10.1 4.4e-06 26.4 0.0 6.5 6 0 0 6 6 6 6 Kelch motif DUF1668 PF07893.13 OQS02125.1 - 0.079 12.3 0.1 0.2 11.0 0.1 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1668) BACK PF07707.15 OQS02125.1 - 0.19 11.9 0.0 0.33 11.1 0.0 1.3 1 0 0 1 1 1 0 BTB And C-terminal Kelch PX PF00787.24 OQS02126.1 - 2.6e-11 43.5 0.8 8.5e-11 41.8 0.2 2.0 2 0 0 2 2 2 1 PX domain ENOD93 PF03386.14 OQS02127.1 - 2.4e-09 36.9 0.7 0.00091 19.1 0.2 2.4 2 0 0 2 2 2 2 Early nodulin 93 ENOD93 protein HIG_1_N PF04588.13 OQS02127.1 - 2.7e-09 37.1 5.6 3.1e-05 24.1 0.1 3.8 4 0 0 4 4 4 2 Hypoxia induced protein conserved region DUF2628 PF10947.8 OQS02129.1 - 1.3 9.4 5.0 5.2 7.5 0.0 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF2628) C2 PF00168.30 OQS02130.1 - 9.6e-96 314.9 0.0 1.2e-19 70.5 0.0 8.8 8 0 0 8 8 8 8 C2 domain FerI PF08151.12 OQS02130.1 - 0.00027 21.0 0.0 0.001 19.1 0.0 2.0 1 0 0 1 1 1 1 FerI (NUC094) domain Ferlin_C PF16165.5 OQS02130.1 - 0.084 12.8 1.0 1.3 8.9 0.0 2.6 2 0 0 2 2 2 0 Ferlin C-terminus Actin PF00022.19 OQS02131.1 - 1.6e-21 76.4 0.3 5.6e-13 48.3 0.0 3.3 2 1 1 3 3 3 2 Actin CSRNP_N PF16019.5 OQS02132.1 - 0.037 13.9 0.2 0.06 13.2 0.2 1.5 1 1 0 1 1 1 0 Cysteine/serine-rich nuclear protein N-terminus Dymeclin PF09742.9 OQS02133.1 - 6.8e-43 147.0 15.4 8.8e-43 146.7 15.4 1.0 1 0 0 1 1 1 1 Dyggve-Melchior-Clausen syndrome protein STIMATE PF12400.8 OQS02133.1 - 0.066 13.8 2.5 0.095 13.3 0.5 2.3 2 0 0 2 2 2 0 STIMATE family FAA_hydro_N_2 PF18288.1 OQS02133.1 - 0.22 11.9 0.7 1 9.8 0.2 2.3 2 0 0 2 2 2 0 Fumarylacetoacetase N-terminal domain 2 Dymeclin PF09742.9 OQS02134.1 - 2.3e-11 42.9 0.1 2.6e-11 42.7 0.1 1.0 1 0 0 1 1 1 1 Dyggve-Melchior-Clausen syndrome protein Ank_2 PF12796.7 OQS02135.1 - 2.1e-30 105.1 4.5 1.2e-15 57.8 0.2 3.3 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQS02135.1 - 2.2e-24 85.5 10.2 7.8e-08 32.7 0.4 5.0 2 2 3 5 5 5 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 OQS02135.1 - 2.8e-20 72.1 6.3 5.5e-08 32.9 0.0 5.5 1 1 3 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQS02135.1 - 4.3e-20 69.7 3.3 0.0013 19.1 0.0 5.9 5 0 0 5 5 5 4 Ankyrin repeat Ank PF00023.30 OQS02135.1 - 4.8e-17 61.6 8.2 0.0002 21.6 0.0 6.0 6 0 0 6 6 6 4 Ankyrin repeat DHHC PF01529.20 OQS02135.1 - 6.6e-05 23.0 14.6 6.6e-05 23.0 14.6 2.7 2 1 0 2 2 2 1 DHHC palmitoyltransferase sCache_like PF16736.5 OQS02135.1 - 0.027 14.6 0.0 0.14 12.2 0.0 2.1 2 0 0 2 2 2 0 Single Cache-like DUF1284 PF06935.11 OQS02135.1 - 1.1 9.8 3.6 2.7 8.5 0.1 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1284) RRM_1 PF00076.22 OQS02136.1 - 8.6e-27 92.8 0.0 6.7e-10 38.7 0.0 4.4 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DEC-1_N PF04625.13 OQS02136.1 - 0.69 8.9 11.1 0.28 10.1 7.3 2.0 2 0 0 2 2 2 0 DEC-1 protein, N-terminal region Apt1 PF10351.9 OQS02136.1 - 6.5 5.5 16.8 8.8 5.1 16.8 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain UQ_con PF00179.26 OQS02137.1 - 1e-17 64.1 0.0 1.5e-17 63.5 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme EF-hand_1 PF00036.32 OQS02137.1 - 1.7e-13 49.1 4.0 3.1e-06 26.3 0.2 2.8 3 0 0 3 3 3 2 EF hand EF-hand_7 PF13499.6 OQS02137.1 - 4.1e-13 49.6 0.5 7.2e-13 48.8 0.5 1.4 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 OQS02137.1 - 4e-11 41.9 1.1 3e-05 23.6 0.1 3.0 2 1 1 3 3 3 2 EF-hand domain EF-hand_5 PF13202.6 OQS02137.1 - 6.8e-11 41.1 5.6 2e-06 27.0 0.3 3.7 2 2 1 3 3 3 2 EF hand EF-hand_8 PF13833.6 OQS02137.1 - 8.7e-09 35.1 3.4 1.2e-05 25.0 0.9 2.5 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_9 PF14658.6 OQS02137.1 - 0.0026 18.0 0.1 0.0047 17.2 0.1 1.4 1 0 0 1 1 1 1 EF-hand domain CCM2_C PF16545.5 OQS02137.1 - 0.015 15.8 0.1 0.23 12.0 0.1 2.4 1 1 1 2 2 2 0 Cerebral cavernous malformation protein, harmonin-homology TerB PF05099.13 OQS02137.1 - 0.034 14.1 0.0 0.065 13.2 0.0 1.6 1 0 0 1 1 1 0 Tellurite resistance protein TerB EF-hand_4 PF12763.7 OQS02137.1 - 0.056 13.4 0.6 0.15 12.1 0.5 1.7 1 1 0 1 1 1 0 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 OQS02137.1 - 0.063 13.6 0.4 0.12 12.7 0.4 1.4 1 0 0 1 1 1 0 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_10 PF14788.6 OQS02137.1 - 0.089 12.7 2.6 0.21 11.5 0.9 2.1 1 1 1 2 2 2 0 EF hand WD40 PF00400.32 OQS02139.1 - 2.8e-38 129.2 10.9 2e-05 25.3 0.0 7.9 9 0 0 9 9 8 6 WD domain, G-beta repeat zf-RING_2 PF13639.6 OQS02139.1 - 8.8e-11 42.0 12.9 8.8e-11 42.0 12.9 2.1 2 0 0 2 2 1 1 Ring finger domain ANAPC4_WD40 PF12894.7 OQS02139.1 - 6.7e-09 35.9 0.0 0.006 16.9 0.0 5.1 2 1 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain zf-rbx1 PF12678.7 OQS02139.1 - 2.4e-07 30.9 10.7 8.2e-07 29.2 10.7 2.0 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_11 PF17123.5 OQS02139.1 - 4.3e-06 26.4 5.1 1.3e-05 24.8 5.1 1.9 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 OQS02139.1 - 2.2e-05 24.2 12.5 2.2e-05 24.2 12.5 2.0 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) Ge1_WD40 PF16529.5 OQS02139.1 - 0.00012 21.1 0.1 0.54 9.1 0.0 4.0 2 2 2 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein zf-ANAPC11 PF12861.7 OQS02139.1 - 0.00072 19.6 4.9 0.0026 17.8 4.9 2.0 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4 PF00097.25 OQS02139.1 - 0.0011 18.8 11.7 0.003 17.4 11.7 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OQS02139.1 - 0.0027 17.7 7.2 0.0027 17.7 7.2 2.1 1 1 1 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 OQS02139.1 - 0.006 16.5 10.2 0.017 15.1 10.2 1.8 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 OQS02139.1 - 0.0062 16.4 10.0 0.0062 16.4 10.0 2.0 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) PX PF00787.24 OQS02139.1 - 0.011 15.7 0.0 0.023 14.7 0.0 1.4 1 0 0 1 1 1 0 PX domain Nup160 PF11715.8 OQS02139.1 - 0.027 13.1 0.2 6.6 5.2 0.0 3.1 1 1 1 3 3 3 0 Nucleoporin Nup120/160 Zn_ribbon_17 PF17120.5 OQS02139.1 - 0.19 11.4 11.8 0.56 9.9 11.8 1.8 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type Prok-RING_4 PF14447.6 OQS02139.1 - 0.2 11.5 13.3 1.4 8.9 13.2 2.4 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 zf_CopZ PF18423.1 OQS02139.1 - 0.39 10.7 7.0 2 8.4 0.0 3.3 3 0 0 3 3 3 0 Zinc binding domain zf-Nse PF11789.8 OQS02139.1 - 1.8 8.4 8.4 3.9 7.4 8.4 1.6 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit DUF1974 PF09317.11 OQS02140.1 - 9.4e-58 196.0 0.1 3.3e-57 194.2 0.1 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF1974) Acyl-CoA_dh_N PF02771.16 OQS02140.1 - 4.4e-17 62.8 0.0 9.7e-17 61.7 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 OQS02140.1 - 3.7e-08 33.4 0.0 1.1e-07 32.0 0.0 1.8 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.24 OQS02140.1 - 3.8e-08 33.7 0.3 7.4e-08 32.7 0.3 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain SAP PF02037.27 OQS02141.1 - 3.3e-12 45.9 0.4 7.9e-12 44.6 0.4 1.7 1 0 0 1 1 1 1 SAP domain HeH PF12949.7 OQS02141.1 - 0.028 14.1 0.1 0.028 14.1 0.1 2.2 3 0 0 3 3 3 0 HeH/LEM domain Myosin_head PF00063.21 OQS02142.1 - 2.2e-220 733.5 0.0 2.7e-220 733.1 0.0 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) CH PF00307.31 OQS02142.1 - 5.1e-13 49.2 0.5 1.5e-12 47.7 0.5 1.9 1 0 0 1 1 1 1 Calponin homology (CH) domain IQ PF00612.27 OQS02142.1 - 0.00011 21.7 1.2 0.19 11.6 0.0 3.5 3 0 0 3 3 3 2 IQ calmodulin-binding motif CDC24 PF06395.11 OQS02142.1 - 0.0011 19.2 0.1 0.0032 17.7 0.1 1.8 1 0 0 1 1 1 1 CDC24 Calponin Myosin_N PF02736.19 OQS02142.1 - 0.0011 18.7 0.3 0.0021 17.9 0.3 1.5 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain GIT_CC PF16559.5 OQS02142.1 - 0.012 15.5 0.1 0.029 14.3 0.1 1.7 1 0 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor AAA_16 PF13191.6 OQS02142.1 - 0.017 15.5 0.0 0.057 13.8 0.0 1.9 1 0 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 OQS02142.1 - 0.046 14.0 0.0 0.22 11.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_6 PF12774.7 OQS02142.1 - 0.09 11.7 0.1 0.19 10.6 0.1 1.5 1 0 0 1 1 1 0 Hydrolytic ATP binding site of dynein motor region CENP-H PF05837.12 OQS02142.1 - 1.3 9.5 4.3 0.75 10.2 0.0 2.5 2 0 0 2 2 2 0 Centromere protein H (CENP-H) SNF2_N PF00176.23 OQS02143.1 - 5.4e-65 219.4 0.2 1.3e-64 218.2 0.0 1.7 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 OQS02143.1 - 2.2e-17 63.4 0.0 5e-17 62.3 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HDA2-3 PF11496.8 OQS02143.1 - 8.1e-07 28.5 0.0 2.4e-06 26.9 0.0 1.7 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 ResIII PF04851.15 OQS02143.1 - 1.4e-06 28.4 0.0 4e-06 26.9 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SWI2_SNF2 PF18766.1 OQS02143.1 - 0.00029 20.6 0.0 0.00078 19.2 0.0 1.8 1 1 0 1 1 1 1 SWI2/SNF2 ATPase AAA_34 PF13872.6 OQS02143.1 - 0.0034 16.3 0.0 0.01 14.7 0.0 1.9 1 0 0 1 1 1 1 P-loop containing NTP hydrolase pore-1 Nop25 PF09805.9 OQS02143.1 - 4.5 7.7 8.3 2.2 8.7 0.0 2.5 2 0 0 2 2 2 0 Nucleolar protein 12 (25kDa) DUF3792 PF12670.7 OQS02144.1 - 1.2 9.4 9.9 0.33 11.1 3.8 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3792) RNase_T PF00929.24 OQS02146.1 - 1.4e-10 42.0 0.0 1.5e-10 41.9 0.0 1.0 1 0 0 1 1 1 1 Exonuclease EF-hand_6 PF13405.6 OQS02147.1 - 0.00021 21.0 0.4 0.0043 16.9 0.0 3.1 3 0 0 3 3 3 1 EF-hand domain EF-hand_1 PF00036.32 OQS02147.1 - 0.0021 17.5 0.0 0.033 13.7 0.0 3.0 3 0 0 3 3 3 1 EF hand EF-hand_7 PF13499.6 OQS02147.1 - 0.0073 16.7 0.9 0.042 14.3 0.2 2.6 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_10 PF14788.6 OQS02147.1 - 0.036 13.9 0.0 0.15 12.0 0.0 2.1 1 0 0 1 1 1 0 EF hand EF-hand_5 PF13202.6 OQS02147.1 - 0.14 11.7 0.0 0.4 10.2 0.0 1.8 1 0 0 1 1 1 0 EF hand EF-hand_2 PF09068.11 OQS02147.1 - 8 6.6 6.7 9.7 6.4 3.5 2.9 2 1 0 2 2 2 0 EF hand ABC2_membrane PF01061.24 OQS02149.1 - 1.9e-37 128.8 28.1 1.9e-37 128.8 28.1 2.0 2 0 0 2 2 2 1 ABC-2 type transporter PDR_assoc PF08370.11 OQS02149.1 - 2.2e-07 30.5 0.5 2.2e-07 30.5 0.5 2.5 2 0 0 2 2 2 1 Plant PDR ABC transporter associated ABC_tran PF00005.27 OQS02149.1 - 2.4e-05 24.8 0.6 3.7e-05 24.2 0.6 1.3 1 0 0 1 1 1 1 ABC transporter AAA_29 PF13555.6 OQS02149.1 - 0.0019 17.9 0.5 0.0049 16.6 0.5 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC2_membrane_3 PF12698.7 OQS02149.1 - 0.0023 17.1 23.0 0.012 14.7 23.0 2.0 1 1 0 1 1 1 1 ABC-2 family transporter protein RsgA_GTPase PF03193.16 OQS02149.1 - 0.0031 17.4 0.2 0.0047 16.8 0.2 1.2 1 0 0 1 1 1 1 RsgA GTPase AAA_23 PF13476.6 OQS02149.1 - 0.19 12.2 0.9 0.31 11.5 0.9 1.3 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 OQS02149.1 - 0.22 11.1 0.1 0.38 10.3 0.1 1.3 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 OQS02150.1 - 2.8e-74 248.1 0.2 1.7e-37 129.0 0.1 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 OQS02150.1 - 3.9e-49 167.8 15.8 5.2e-49 167.3 15.8 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.19 OQS02150.1 - 7.6e-17 61.5 0.0 4.4e-06 26.3 0.0 3.8 2 2 1 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 OQS02150.1 - 1.1e-09 38.7 1.9 0.0017 18.6 0.3 3.7 2 2 0 2 2 2 2 AAA domain ABC_ATPase PF09818.9 OQS02150.1 - 8.8e-09 34.7 2.0 0.0048 15.8 0.1 3.4 3 0 0 3 3 3 2 Predicted ATPase of the ABC class RsgA_GTPase PF03193.16 OQS02150.1 - 4.9e-08 33.1 0.2 0.023 14.6 0.0 3.1 3 0 0 3 3 2 2 RsgA GTPase AAA_29 PF13555.6 OQS02150.1 - 1.2e-07 31.3 0.1 0.0036 17.0 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 OQS02150.1 - 2.5e-07 31.2 2.6 0.0053 17.2 0.3 2.9 2 2 0 2 2 2 2 AAA ATPase domain AAA_5 PF07728.14 OQS02150.1 - 1.9e-06 27.9 1.7 0.14 12.2 0.0 4.4 4 0 0 4 4 4 1 AAA domain (dynein-related subfamily) APS_kinase PF01583.20 OQS02150.1 - 1.2e-05 25.2 0.1 0.14 12.0 0.0 2.6 2 0 0 2 2 2 2 Adenylylsulphate kinase SbcCD_C PF13558.6 OQS02150.1 - 2.5e-05 24.4 3.7 0.52 10.6 0.4 4.2 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_30 PF13604.6 OQS02150.1 - 3.5e-05 23.6 5.2 0.16 11.6 1.2 3.8 2 2 0 2 2 2 2 AAA domain AAA_25 PF13481.6 OQS02150.1 - 4.2e-05 23.2 1.1 2 8.0 0.0 4.5 5 0 0 5 5 4 1 AAA domain AAA_33 PF13671.6 OQS02150.1 - 0.00021 21.5 0.1 0.87 9.7 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_15 PF13175.6 OQS02150.1 - 0.00032 20.5 0.0 0.6 9.8 0.0 2.4 2 1 0 2 2 2 2 AAA ATPase domain AAA PF00004.29 OQS02150.1 - 0.00035 21.0 10.0 0.82 10.1 0.5 4.8 3 2 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) G-alpha PF00503.20 OQS02150.1 - 0.00045 19.5 0.1 0.095 11.8 0.0 2.3 2 0 0 2 2 2 1 G-protein alpha subunit AAA_7 PF12775.7 OQS02150.1 - 0.00059 19.4 0.1 1.5 8.3 0.0 2.8 2 0 0 2 2 2 2 P-loop containing dynein motor region SRP54 PF00448.22 OQS02150.1 - 0.00079 19.1 0.1 1.4 8.5 0.0 2.6 2 0 0 2 2 2 2 SRP54-type protein, GTPase domain AAA_28 PF13521.6 OQS02150.1 - 0.00098 19.4 0.2 1.3 9.2 0.0 2.9 2 0 0 2 2 2 1 AAA domain DEAD PF00270.29 OQS02150.1 - 0.0011 18.8 3.9 0.12 12.1 0.4 4.0 2 2 0 2 2 2 1 DEAD/DEAH box helicase Zeta_toxin PF06414.12 OQS02150.1 - 0.0014 18.0 0.1 0.47 9.7 0.0 2.6 2 0 0 2 2 2 1 Zeta toxin AAA_18 PF13238.6 OQS02150.1 - 0.0022 18.6 0.2 4.4 7.9 0.0 3.2 2 1 0 2 2 2 0 AAA domain DUF87 PF01935.17 OQS02150.1 - 0.0024 18.0 4.3 0.039 14.1 0.1 3.4 4 1 1 5 5 4 1 Helicase HerA, central domain IstB_IS21 PF01695.17 OQS02150.1 - 0.0027 17.5 0.6 8.6 6.1 0.0 3.8 4 0 0 4 4 4 0 IstB-like ATP binding protein MoaE PF02391.17 OQS02150.1 - 0.005 17.1 0.5 0.51 10.6 0.1 2.7 2 0 0 2 2 2 1 MoaE protein DUF815 PF05673.13 OQS02150.1 - 0.0064 15.7 0.0 1.3 8.1 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF815) Rad17 PF03215.15 OQS02150.1 - 0.0069 16.3 0.1 0.49 10.3 0.0 2.9 3 0 0 3 3 3 1 Rad17 P-loop domain KAP_NTPase PF07693.14 OQS02150.1 - 0.0091 15.3 0.0 0.7 9.1 0.0 2.5 2 0 0 2 2 2 1 KAP family P-loop domain PRK PF00485.18 OQS02150.1 - 0.011 15.5 0.1 3.8 7.2 0.0 2.6 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family AAA_23 PF13476.6 OQS02150.1 - 0.013 16.1 0.2 4.6 7.7 0.0 2.4 2 0 0 2 2 2 0 AAA domain TniB PF05621.11 OQS02150.1 - 0.017 14.6 0.2 5.5 6.4 0.1 3.5 4 0 0 4 4 4 0 Bacterial TniB protein AAA_21 PF13304.6 OQS02150.1 - 0.017 14.9 0.1 4.7 6.9 0.0 3.2 2 1 1 3 3 3 0 AAA domain, putative AbiEii toxin, Type IV TA system RNA_helicase PF00910.22 OQS02150.1 - 0.018 15.4 0.1 9 6.7 0.0 2.8 2 0 0 2 2 2 0 RNA helicase AAA_24 PF13479.6 OQS02150.1 - 0.018 14.8 0.2 1.4 8.6 0.0 2.9 2 0 0 2 2 2 0 AAA domain ATP_bind_1 PF03029.17 OQS02150.1 - 0.036 13.9 0.3 9.9 5.9 0.0 2.5 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein MMR_HSR1 PF01926.23 OQS02150.1 - 0.067 13.3 0.0 2 8.5 0.0 2.8 2 0 0 2 2 2 0 50S ribosome-binding GTPase NACHT PF05729.12 OQS02150.1 - 0.074 13.0 3.8 1.6 8.6 0.1 3.7 4 0 0 4 4 4 0 NACHT domain Ploopntkinase3 PF18751.1 OQS02150.1 - 0.094 12.6 0.3 2.9 7.7 0.0 2.7 3 0 0 3 3 2 0 P-loop Nucleotide Kinase3 Roc PF08477.13 OQS02150.1 - 0.1 12.8 0.0 19 5.5 0.0 2.9 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase RepB-RCR_reg PF10723.9 OQS02150.1 - 0.14 12.1 0.0 27 4.8 0.0 2.7 2 0 0 2 2 2 0 Replication regulatory protein RepB CCDC53 PF10152.9 OQS02151.1 - 8.8e-45 152.9 15.2 2.4e-14 54.0 1.4 4.1 3 1 1 4 4 4 4 Subunit CCDC53 of WASH complex Drf_FH3 PF06367.16 OQS02151.1 - 7.3e-05 22.5 0.1 0.00014 21.5 0.1 1.4 1 0 0 1 1 1 1 Diaphanous FH3 Domain Nitroreductase PF00881.24 OQS02151.1 - 0.00038 20.5 0.0 1 9.4 0.0 2.9 1 1 2 3 3 3 2 Nitroreductase family DUF951 PF06107.11 OQS02151.1 - 0.016 15.1 0.0 75 3.3 0.0 4.0 4 0 0 4 4 4 0 Bacterial protein of unknown function (DUF951) Drf_FH3 PF06367.16 OQS02152.1 - 2.6e-16 59.8 0.3 5.9e-16 58.7 0.3 1.6 1 0 0 1 1 1 1 Diaphanous FH3 Domain Drf_GBD PF06371.13 OQS02152.1 - 2.6e-07 30.4 0.0 5.4e-07 29.4 0.0 1.5 1 0 0 1 1 1 1 Diaphanous GTPase-binding Domain V_ATPase_I PF01496.19 OQS02153.1 - 3.5e-190 633.9 8.6 4.6e-190 633.5 8.6 1.1 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family cNMP_binding PF00027.29 OQS02154.1 - 3.5e-18 65.5 0.2 1.5e-09 37.7 0.0 3.3 2 1 0 2 2 2 2 Cyclic nucleotide-binding domain RRM_1 PF00076.22 OQS02155.1 - 3.4e-19 68.4 0.0 6.4e-19 67.5 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 OQS02155.1 - 0.042 13.5 0.0 0.048 13.2 0.0 1.2 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 OQS02155.1 - 0.083 13.0 0.1 0.21 11.7 0.0 1.8 1 1 0 1 1 1 0 RNA recognition motif WD40 PF00400.32 OQS02156.1 - 3.6e-21 75.1 12.6 0.00021 22.0 0.3 10.0 10 1 0 10 10 10 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OQS02156.1 - 6.6e-10 39.2 0.1 0.014 15.6 0.0 6.6 5 2 2 7 7 7 1 Anaphase-promoting complex subunit 4 WD40 domain KASH_CCD PF14662.6 OQS02156.1 - 0.002 18.0 19.4 0.002 18.0 19.4 3.3 1 1 3 4 4 4 2 Coiled-coil region of CCDC155 or KASH CENP-F_leu_zip PF10473.9 OQS02156.1 - 0.0025 17.8 13.4 0.0025 17.8 13.4 4.4 1 1 4 5 5 5 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Fez1 PF06818.15 OQS02156.1 - 0.0063 17.0 16.1 0.0063 17.0 16.1 3.1 1 1 2 3 3 3 1 Fez1 ADIP PF11559.8 OQS02156.1 - 0.0092 16.1 13.1 0.0092 16.1 13.1 4.2 1 1 3 4 4 4 1 Afadin- and alpha -actinin-Binding DUF4407 PF14362.6 OQS02156.1 - 0.43 9.9 37.5 0.41 10.0 13.8 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) Annexin PF00191.20 OQS02157.1 - 1.5e-49 165.9 0.2 3.6e-12 46.2 0.0 4.4 4 0 0 4 4 4 4 Annexin Ank_2 PF12796.7 OQS02158.1 - 2.5e-13 50.4 1.6 5.1e-07 30.2 0.1 2.7 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQS02158.1 - 2.7e-10 40.6 0.1 2e-05 25.0 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQS02158.1 - 1.9e-06 27.7 0.1 2 9.2 0.0 4.2 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.6 OQS02158.1 - 2.8e-06 27.5 0.1 0.15 12.4 0.1 3.3 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 OQS02158.1 - 0.14 12.7 0.1 29 5.4 0.1 3.6 3 1 0 3 3 3 0 Ankyrin repeat Annexin PF00191.20 OQS02160.1 - 1.8e-29 101.6 0.0 3.9e-14 52.5 0.0 2.2 2 0 0 2 2 2 2 Annexin SapB_2 PF03489.17 OQS02161.1 - 0.0053 16.8 9.1 0.015 15.4 1.7 2.5 2 0 0 2 2 2 2 Saposin-like type B, region 2 cNMP_binding PF00027.29 OQS02162.1 - 6.7e-46 154.3 0.3 1.1e-21 76.7 0.1 2.7 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain Pkinase PF00069.25 OQS02162.1 - 1.7e-14 53.9 0.2 2.9e-14 53.1 0.2 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQS02162.1 - 5.2e-08 32.5 0.1 8.7e-08 31.8 0.1 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase 7TMR-HDED PF07697.11 OQS02162.1 - 0.0072 16.5 0.6 0.7 10.0 0.1 2.7 3 0 0 3 3 3 1 7TM-HD extracellular ASXH PF13919.6 OQS02162.1 - 0.087 12.8 0.0 0.39 10.7 0.0 2.0 2 0 0 2 2 2 0 Asx homology domain Phage_pRha PF09669.10 OQS02162.1 - 0.093 13.3 0.9 13 6.4 0.0 3.1 3 0 0 3 3 3 0 Phage regulatory protein Rha (Phage_pRha) GAF PF01590.26 OQS02163.1 - 2.4e-06 28.2 0.0 2.9e-06 27.9 0.0 1.2 1 0 0 1 1 1 1 GAF domain Myosin_head PF00063.21 OQS02165.1 - 6.4e-110 368.4 0.4 9.7e-110 367.8 0.4 1.3 1 0 0 1 1 1 1 Myosin head (motor domain) PX PF00787.24 OQS02165.1 - 2.3e-11 43.7 0.3 7.2e-11 42.1 0.3 1.8 1 0 0 1 1 1 1 PX domain IQ PF00612.27 OQS02165.1 - 2.8e-09 36.0 22.6 0.00093 18.8 3.1 4.1 3 0 0 3 3 3 3 IQ calmodulin-binding motif HALZ PF02183.18 OQS02165.1 - 0.61 10.4 6.5 1.7 9.0 1.8 3.0 3 0 0 3 3 3 0 Homeobox associated leucine zipper AAA PF00004.29 OQS02166.1 - 5.7e-71 237.1 0.0 1e-37 129.5 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 OQS02166.1 - 2.5e-26 91.2 0.2 8.4e-16 57.5 0.0 2.6 2 0 0 2 2 2 2 AAA+ lid domain AAA_16 PF13191.6 OQS02166.1 - 1.5e-13 51.5 0.6 3.7e-06 27.4 0.3 3.0 2 1 0 2 2 2 2 AAA ATPase domain AAA_5 PF07728.14 OQS02166.1 - 1.4e-09 38.1 0.0 0.0014 18.6 0.0 3.0 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 OQS02166.1 - 6.8e-07 29.6 2.3 0.0015 18.8 0.3 4.4 3 2 1 4 4 3 1 AAA domain AAA_2 PF07724.14 OQS02166.1 - 5.5e-06 26.6 0.0 0.016 15.4 0.0 2.4 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) DUF815 PF05673.13 OQS02166.1 - 3.3e-05 23.2 0.0 0.18 11.0 0.0 2.9 3 0 0 3 3 3 2 Protein of unknown function (DUF815) TIP49 PF06068.13 OQS02166.1 - 3.8e-05 23.0 0.0 0.23 10.6 0.0 2.3 2 0 0 2 2 2 2 TIP49 P-loop domain RuvB_N PF05496.12 OQS02166.1 - 0.0002 21.1 0.0 0.6 9.8 0.0 2.7 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain RNA_helicase PF00910.22 OQS02166.1 - 0.00035 20.9 0.0 1.6 9.1 0.0 2.6 2 0 0 2 2 2 2 RNA helicase AAA_7 PF12775.7 OQS02166.1 - 0.00035 20.1 0.0 0.13 11.7 0.0 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region Rad17 PF03215.15 OQS02166.1 - 0.00042 20.3 0.4 0.081 12.8 0.1 2.6 2 1 0 2 2 2 1 Rad17 P-loop domain ABC_tran PF00005.27 OQS02166.1 - 0.001 19.6 0.0 0.39 11.2 0.0 2.8 2 1 0 2 2 2 1 ABC transporter NTPase_1 PF03266.15 OQS02166.1 - 0.0011 18.8 0.3 0.062 13.2 0.1 2.7 3 0 0 3 3 3 1 NTPase AAA_33 PF13671.6 OQS02166.1 - 0.0025 18.0 0.0 2.3 8.4 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.6 OQS02166.1 - 0.0027 17.7 0.0 0.62 10.1 0.0 2.4 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.21 OQS02166.1 - 0.0058 16.0 0.1 0.9 8.9 0.0 2.7 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_29 PF13555.6 OQS02166.1 - 0.011 15.4 0.0 4.4 7.1 0.0 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain TsaE PF02367.17 OQS02166.1 - 0.012 15.6 0.0 0.25 11.4 0.0 2.4 2 1 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_30 PF13604.6 OQS02166.1 - 0.013 15.2 0.0 0.47 10.1 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 OQS02166.1 - 0.018 15.6 0.0 0.69 10.5 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.6 OQS02166.1 - 0.026 14.9 0.2 0.39 11.0 0.1 2.4 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 OQS02166.1 - 0.027 13.8 0.0 0.65 9.2 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin NACHT PF05729.12 OQS02166.1 - 0.042 13.8 0.1 1.1 9.2 0.1 3.1 2 1 0 2 2 2 0 NACHT domain IstB_IS21 PF01695.17 OQS02166.1 - 0.057 13.1 0.0 4.5 7.0 0.0 2.4 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_11 PF13086.6 OQS02166.1 - 0.063 13.1 0.0 2.7 7.7 0.0 2.3 2 0 0 2 2 2 0 AAA domain CDC48_2 PF02933.17 OQS02166.1 - 0.063 13.1 0.0 0.17 11.7 0.0 1.7 1 0 0 1 1 1 0 Cell division protein 48 (CDC48), domain 2 AAA_3 PF07726.11 OQS02166.1 - 0.068 13.0 0.0 1.7 8.5 0.0 2.4 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) ATPase_2 PF01637.18 OQS02166.1 - 0.072 13.0 0.1 6.3 6.6 0.0 2.7 2 1 1 3 3 3 0 ATPase domain predominantly from Archaea AAA_25 PF13481.6 OQS02166.1 - 0.083 12.4 0.9 22 4.5 0.0 3.3 3 1 1 4 4 4 0 AAA domain NB-ARC PF00931.22 OQS02166.1 - 0.12 11.6 0.0 3.1 6.9 0.0 2.6 3 0 0 3 3 3 0 NB-ARC domain AAA_24 PF13479.6 OQS02166.1 - 0.16 11.7 0.0 4.3 7.0 0.0 2.2 2 0 0 2 2 2 0 AAA domain Longin PF13774.6 OQS02167.1 - 1.5e-13 50.6 0.0 2.2e-13 50.0 0.0 1.2 1 0 0 1 1 1 1 Regulated-SNARE-like domain ZZ PF00569.17 OQS02168.1 - 5.4e-09 35.7 2.9 9.6e-09 34.9 2.9 1.4 1 0 0 1 1 1 1 Zinc finger, ZZ type RabGAP-TBC PF00566.18 OQS02169.1 - 2.1e-12 47.2 0.1 3.3e-12 46.5 0.1 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain WW PF00397.26 OQS02169.1 - 1e-05 25.5 2.1 2.2e-05 24.4 2.1 1.6 1 0 0 1 1 1 1 WW domain Rhodanese PF00581.20 OQS02169.1 - 0.049 14.1 0.0 0.24 11.9 0.0 2.2 1 1 0 1 1 1 0 Rhodanese-like domain DUF3527 PF12043.8 OQS02169.1 - 0.052 13.1 0.0 0.081 12.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3527) Ins145_P3_rec PF08709.11 OQS02173.1 - 3.1e-29 101.7 1.7 1.1e-28 99.9 0.7 2.3 1 1 1 2 2 2 1 Inositol 1,4,5-trisphosphate/ryanodine receptor RYDR_ITPR PF01365.21 OQS02173.1 - 4.6e-14 52.3 18.6 1.4e-11 44.2 1.2 4.5 4 1 1 5 5 5 2 RIH domain RIH_assoc PF08454.11 OQS02173.1 - 1.2e-12 47.6 1.9 1.2e-12 47.6 1.9 5.2 7 0 0 7 7 7 1 RyR and IP3R Homology associated MIR PF02815.19 OQS02173.1 - 2.7e-12 46.9 3.4 8.7e-09 35.5 0.0 2.6 2 0 0 2 2 2 2 MIR domain Ion_trans PF00520.31 OQS02173.1 - 1.2e-09 37.8 13.7 1.2e-09 37.8 13.7 2.7 2 0 0 2 2 2 1 Ion transport protein Ins145_P3_rec PF08709.11 OQS02174.1 - 8.4e-29 100.3 0.1 1.6e-28 99.4 0.1 1.4 1 0 0 1 1 1 1 Inositol 1,4,5-trisphosphate/ryanodine receptor MIR PF02815.19 OQS02174.1 - 4.4e-10 39.7 0.9 1.1e-06 28.6 0.1 3.0 1 1 1 2 2 2 2 MIR domain FGF PF00167.18 OQS02174.1 - 0.0049 17.0 0.4 0.7 10.0 0.0 3.1 3 0 0 3 3 3 1 Fibroblast growth factor zf-RING_2 PF13639.6 OQS02175.1 - 1.9e-10 40.9 13.0 2.9e-10 40.3 13.0 1.3 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 OQS02175.1 - 2.2e-08 34.3 11.6 4.9e-08 33.1 11.6 1.6 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 OQS02175.1 - 3.5e-06 26.9 8.5 6.3e-06 26.1 8.5 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_11 PF17123.5 OQS02175.1 - 1.1e-05 25.1 7.4 1.9e-05 24.3 7.4 1.4 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_3 PF13920.6 OQS02175.1 - 2.7e-05 23.9 9.7 4.1e-05 23.3 9.7 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 OQS02175.1 - 8.9e-05 22.3 12.8 0.00014 21.7 12.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 OQS02175.1 - 9.5e-05 22.2 12.8 0.00015 21.5 12.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OQS02175.1 - 0.0001 22.2 9.8 0.00016 21.6 9.8 1.3 1 0 0 1 1 1 1 zinc-RING finger domain Zn_ribbon_17 PF17120.5 OQS02175.1 - 0.00077 19.0 4.9 0.0012 18.5 4.9 1.2 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type Prok-RING_4 PF14447.6 OQS02175.1 - 0.013 15.4 9.1 0.022 14.6 9.1 1.3 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 OQS02175.1 - 0.015 15.4 8.0 0.044 13.8 8.0 1.8 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-HC5HC2H PF13771.6 OQS02175.1 - 0.03 14.6 2.3 0.058 13.7 2.3 1.4 1 0 0 1 1 1 0 PHD-like zinc-binding domain FANCL_C PF11793.8 OQS02175.1 - 0.052 13.7 8.0 0.14 12.3 8.0 1.7 1 1 0 1 1 1 0 FANCL C-terminal domain zf-P11 PF03854.14 OQS02175.1 - 0.38 10.5 4.7 0.87 9.3 4.7 1.6 1 0 0 1 1 1 0 P-11 zinc finger zf-RING-like PF08746.11 OQS02175.1 - 0.39 11.1 9.5 0.58 10.5 9.5 1.3 1 0 0 1 1 1 0 RING-like domain RINGv PF12906.7 OQS02175.1 - 1.6 8.9 11.4 3.2 7.9 11.4 1.4 1 0 0 1 1 1 0 RING-variant domain Zf_RING PF16744.5 OQS02175.1 - 2.9 8.1 5.8 5.1 7.3 5.8 1.3 1 0 0 1 1 1 0 KIAA1045 RING finger DZR PF12773.7 OQS02175.1 - 4.4 7.4 6.5 13 5.9 0.6 2.1 1 1 1 2 2 2 0 Double zinc ribbon PHD PF00628.29 OQS02175.1 - 9.6 6.2 8.2 17 5.4 8.2 1.4 1 0 0 1 1 1 0 PHD-finger FLYWCH PF04500.16 OQS02177.1 - 0.012 15.7 0.5 0.023 14.8 0.5 1.5 1 0 0 1 1 1 0 FLYWCH zinc finger domain Cpn60_TCP1 PF00118.24 OQS02178.1 - 1e-162 542.2 1.4 1.3e-162 541.9 1.4 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Brix PF04427.18 OQS02179.1 - 7.7e-42 143.6 0.2 1.1e-41 143.0 0.2 1.3 1 0 0 1 1 1 1 Brix domain DNA_pol_A_exo1 PF01612.20 OQS02180.1 - 1.1e-17 64.3 0.7 1.7e-17 63.7 0.7 1.3 1 0 0 1 1 1 1 3'-5' exonuclease zf-C2H2_jaz PF12171.8 OQS02180.1 - 7.3e-08 32.5 4.8 0.0047 17.2 0.0 3.7 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 OQS02180.1 - 1.1e-05 25.7 6.9 0.0053 17.1 0.0 3.7 3 0 0 3 3 3 1 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 OQS02180.1 - 0.00024 21.7 21.7 0.1 13.5 1.2 4.3 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2H2 PF00096.26 OQS02180.1 - 0.0087 16.5 17.1 1.2 9.8 0.1 4.2 4 1 1 5 5 5 3 Zinc finger, C2H2 type zf-C2H2_11 PF16622.5 OQS02180.1 - 0.011 15.5 4.2 0.22 11.3 2.0 2.7 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-C2H2_8 PF15909.5 OQS02180.1 - 0.33 11.3 5.5 0.4 11.0 0.8 2.6 2 0 0 2 2 2 0 C2H2-type zinc ribbon zf-H2C2_2 PF13465.6 OQS02180.1 - 7.2 7.2 13.5 0.99 10.0 1.1 3.6 2 1 1 3 3 3 0 Zinc-finger double domain Mannosyl_trans PF05007.13 OQS02181.1 - 2.6e-45 155.3 8.6 2.6e-45 155.3 8.6 1.8 2 0 0 2 2 2 1 Mannosyltransferase (PIG-M) PIG-U PF06728.13 OQS02181.1 - 2.2e-10 40.1 17.4 2.5e-10 40.0 17.4 1.1 1 0 0 1 1 1 1 GPI transamidase subunit PIG-U GT87 PF09594.10 OQS02181.1 - 8e-08 32.3 8.5 8e-08 32.3 8.5 2.0 1 1 1 2 2 2 1 Glycosyltransferase family 87 PMT_2 PF13231.6 OQS02181.1 - 0.0016 18.7 6.9 0.0016 18.7 6.9 2.0 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase DUF4064 PF13273.6 OQS02181.1 - 8.2 6.8 9.9 0.39 11.0 2.1 2.7 3 1 0 3 3 3 0 Protein of unknown function (DUF4064) DEAD PF00270.29 OQS02182.1 - 3.9e-40 137.5 0.2 6.3e-40 136.8 0.2 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OQS02182.1 - 4.2e-29 101.1 1.4 8.8e-29 100.1 0.0 2.3 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 OQS02182.1 - 6.2e-10 39.3 1.1 1.7e-09 37.9 0.0 2.3 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit T4SS-DNA_transf PF02534.14 OQS02182.1 - 0.011 14.5 0.0 0.019 13.8 0.0 1.3 1 0 0 1 1 1 0 Type IV secretory system Conjugative DNA transfer Helicase_C_2 PF13307.6 OQS02182.1 - 0.056 13.6 0.0 0.14 12.3 0.0 1.6 1 0 0 1 1 1 0 Helicase C-terminal domain AMP_N PF05195.16 OQS02182.1 - 0.13 12.0 0.0 1.4 8.7 0.0 2.4 2 0 0 2 2 2 0 Aminopeptidase P, N-terminal domain CENP-B_dimeris PF09026.10 OQS02182.1 - 1.3 9.5 8.4 2.6 8.5 8.4 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Sel1 PF08238.12 OQS02184.1 - 7.2e-45 150.4 20.6 8.3e-07 29.5 0.6 11.0 12 0 0 12 12 12 6 Sel1 repeat Laminin_G_3 PF13385.6 OQS02184.1 - 1.9e-11 44.3 0.1 4.2e-11 43.2 0.1 1.6 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily TPR_6 PF13174.6 OQS02184.1 - 0.00021 21.7 2.9 2.9 8.7 0.0 4.9 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_2 PF07719.17 OQS02184.1 - 0.075 13.2 0.1 0.075 13.2 0.1 7.1 10 0 0 10 10 10 0 Tetratricopeptide repeat TPR_1 PF00515.28 OQS02184.1 - 0.1 12.5 0.0 0.1 12.5 0.0 8.1 10 0 0 10 10 10 0 Tetratricopeptide repeat TPR_16 PF13432.6 OQS02184.1 - 0.18 12.5 4.1 9.3 7.0 0.1 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 OQS02184.1 - 0.3 12.0 2.9 4.3 8.4 0.0 4.4 7 0 0 7 7 7 0 Tetratricopeptide repeat Pkinase PF00069.25 OQS02185.1 - 2.9e-61 207.2 0.0 3.6e-61 206.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQS02185.1 - 8.2e-29 100.7 0.0 1e-28 100.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OQS02185.1 - 1.4e-08 34.4 0.0 2e-08 33.9 0.0 1.2 1 0 0 1 1 1 1 Kinase-like PH PF00169.29 OQS02185.1 - 5.3e-06 26.9 0.0 9.5e-06 26.1 0.0 1.4 1 0 0 1 1 1 1 PH domain Pkinase_fungal PF17667.1 OQS02185.1 - 0.00017 20.5 0.1 0.00028 19.8 0.1 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 OQS02185.1 - 0.016 14.5 0.0 0.034 13.5 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_C PF00433.24 OQS02185.1 - 0.02 15.6 6.3 0.05 14.3 6.3 1.7 1 0 0 1 1 1 0 Protein kinase C terminal domain FTA2 PF13095.6 OQS02185.1 - 0.02 14.5 0.1 2.5 7.7 0.0 2.2 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Seadorna_VP7 PF07387.11 OQS02185.1 - 0.043 12.9 0.0 0.16 11.0 0.1 1.8 2 0 0 2 2 2 0 Seadornavirus VP7 APH PF01636.23 OQS02185.1 - 0.044 13.7 0.5 0.3 11.0 0.6 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 OQS02185.1 - 0.11 11.4 0.0 0.16 10.9 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain RRM_1 PF00076.22 OQS02186.1 - 1.4e-06 28.0 0.0 0.046 13.5 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HEAT PF02985.22 OQS02186.1 - 0.089 13.1 2.5 28 5.4 0.1 3.8 3 0 0 3 3 3 0 HEAT repeat TPR_4 PF07721.14 OQS02187.1 - 0.33 11.7 2.6 15 6.6 0.2 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat Snf7 PF03357.21 OQS02187.1 - 0.75 9.4 18.8 0.067 12.8 1.5 3.7 4 0 0 4 4 4 0 Snf7 TPR_14 PF13428.6 OQS02187.1 - 0.98 10.4 9.9 9.7 7.3 0.0 5.3 4 2 1 5 5 5 0 Tetratricopeptide repeat TPR_6 PF13174.6 OQS02187.1 - 8.4 7.3 6.0 1.3e+02 3.6 0.1 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.17 OQS02188.1 - 1.3e-28 96.7 16.8 0.001 19.0 0.0 10.7 11 0 0 11 11 11 7 Tetratricopeptide repeat TPR_16 PF13432.6 OQS02188.1 - 2.5e-22 79.2 11.5 3.4e-07 30.8 0.0 5.6 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_11 PF13414.6 OQS02188.1 - 7.8e-22 76.7 1.7 0.00099 18.7 0.0 8.3 6 1 2 8 8 8 5 TPR repeat TPR_8 PF13181.6 OQS02188.1 - 1.4e-19 68.5 14.4 0.0049 17.0 0.0 10.0 10 0 0 10 10 10 4 Tetratricopeptide repeat TPR_12 PF13424.6 OQS02188.1 - 2.1e-19 69.6 16.6 0.00024 21.3 0.4 7.2 4 1 4 8 8 8 6 Tetratricopeptide repeat TPR_14 PF13428.6 OQS02188.1 - 2.3e-18 65.3 10.5 0.0027 18.4 0.1 8.6 5 2 4 9 9 8 4 Tetratricopeptide repeat TPR_1 PF00515.28 OQS02188.1 - 4.6e-18 64.2 20.0 0.027 14.3 0.0 10.5 11 0 0 11 11 11 3 Tetratricopeptide repeat TPR_19 PF14559.6 OQS02188.1 - 5.5e-18 65.2 7.8 1.4e-06 28.7 0.2 6.2 4 1 2 6 6 6 4 Tetratricopeptide repeat TPR_9 PF13371.6 OQS02188.1 - 2.2e-11 43.7 3.8 0.0054 16.9 0.0 4.3 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_7 PF13176.6 OQS02188.1 - 2.9e-11 42.6 10.2 0.46 10.6 0.1 9.0 10 0 0 10 10 10 2 Tetratricopeptide repeat ANAPC3 PF12895.7 OQS02188.1 - 1.6e-08 34.7 8.2 0.13 12.6 0.1 6.2 3 1 4 7 7 7 5 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.6 OQS02188.1 - 9.1e-08 31.7 19.4 0.044 13.7 0.0 8.6 10 0 0 10 10 9 2 Tetratricopeptide repeat TPR_17 PF13431.6 OQS02188.1 - 3.4e-07 30.2 0.2 15 6.3 0.0 7.1 7 0 0 7 7 7 0 Tetratricopeptide repeat NARP1 PF12569.8 OQS02188.1 - 3.9e-06 26.1 5.4 3.1e-05 23.1 0.1 3.5 3 1 0 3 3 3 1 NMDA receptor-regulated protein 1 TPR_MalT PF17874.1 OQS02188.1 - 0.00036 20.0 0.7 0.5 9.7 0.1 2.9 1 1 1 2 2 2 2 MalT-like TPR region TPR_4 PF07721.14 OQS02188.1 - 0.00082 19.8 12.5 0.23 12.2 0.0 5.5 7 0 0 7 7 5 2 Tetratricopeptide repeat TPR_20 PF14561.6 OQS02188.1 - 0.0082 16.5 0.3 0.67 10.3 0.2 3.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.6 OQS02188.1 - 0.017 15.7 15.5 12 6.8 0.0 7.3 8 0 0 8 8 8 0 Tetratricopeptide repeat MAS20 PF02064.15 OQS02188.1 - 0.047 13.8 0.4 47 4.1 0.0 4.2 2 1 3 5 5 5 0 MAS20 protein import receptor TPR_21 PF09976.9 OQS02188.1 - 0.062 13.0 3.9 0.12 12.0 0.0 3.2 4 0 0 4 4 4 0 Tetratricopeptide repeat-like domain DUF4248 PF14053.6 OQS02188.1 - 0.077 13.0 0.0 2.3 8.3 0.0 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4248) RPN7 PF10602.9 OQS02188.1 - 1.7 8.3 6.8 0.64 9.7 0.1 3.4 4 0 0 4 4 4 0 26S proteasome subunit RPN7 Abhydrolase_1 PF00561.20 OQS02189.1 - 1.6e-06 28.0 0.1 3.7e-06 26.8 0.0 1.6 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_4 PF08386.10 OQS02189.1 - 0.00051 20.1 0.0 0.0011 19.0 0.0 1.6 1 0 0 1 1 1 1 TAP-like protein Hydrolase_4 PF12146.8 OQS02189.1 - 0.001 18.4 0.0 0.68 9.1 0.0 2.5 3 0 0 3 3 3 2 Serine aminopeptidase, S33 HSP70 PF00012.20 OQS02190.1 - 3.6e-70 236.8 2.3 3.9e-70 236.7 2.3 1.0 1 0 0 1 1 1 1 Hsp70 protein DUF4635 PF15466.6 OQS02190.1 - 0.0076 15.8 0.7 0.015 14.8 0.7 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4635) SHS2_FTSA PF02491.20 OQS02190.1 - 0.096 13.1 0.2 0.23 11.9 0.2 1.6 1 0 0 1 1 1 0 SHS2 domain inserted in FTSA FHA PF00498.26 OQS02191.1 - 1.3e-17 63.9 0.0 3.5e-13 49.7 0.0 2.4 2 0 0 2 2 2 2 FHA domain Yop-YscD_cpl PF16697.5 OQS02191.1 - 9.6e-08 32.2 0.1 3.6e-07 30.4 0.0 1.9 2 0 0 2 2 2 1 Inner membrane component of T3SS, cytoplasmic domain F-box PF00646.33 OQS02192.1 - 6.2e-06 26.0 0.5 6.2e-06 26.0 0.5 2.2 3 0 0 3 3 3 1 F-box domain F-box-like PF12937.7 OQS02192.1 - 4.3e-05 23.3 0.2 0.00011 22.0 0.2 1.7 1 0 0 1 1 1 1 F-box-like Pkinase PF00069.25 OQS02193.1 - 3.5e-64 216.7 0.0 5.3e-64 216.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQS02193.1 - 2.3e-30 105.7 0.0 3.7e-30 105.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase cNMP_binding PF00027.29 OQS02193.1 - 3.8e-23 81.4 0.0 4.6e-11 42.7 0.0 2.9 3 0 0 3 3 3 2 Cyclic nucleotide-binding domain Kinase-like PF14531.6 OQS02193.1 - 1.3e-06 28.0 0.0 5.3e-06 25.9 0.0 1.9 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 OQS02193.1 - 6.4e-05 21.9 0.0 8.3e-05 21.5 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 OQS02193.1 - 6.6e-05 22.4 0.0 0.00014 21.3 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OQS02193.1 - 0.00011 22.2 0.0 0.00022 21.3 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family FTA2 PF13095.6 OQS02193.1 - 0.0034 17.0 0.1 0.0079 15.8 0.0 1.7 2 0 0 2 2 2 1 Kinetochore Sim4 complex subunit FTA2 EF-hand_8 PF13833.6 OQS02193.1 - 0.0039 17.0 0.2 0.031 14.1 0.0 2.4 1 1 1 2 2 2 2 EF-hand domain pair RIO1 PF01163.22 OQS02193.1 - 0.0051 16.4 0.0 0.013 15.1 0.0 1.6 1 0 0 1 1 1 1 RIO1 family EF-hand_7 PF13499.6 OQS02193.1 - 0.014 15.8 0.0 0.042 14.3 0.0 1.8 1 0 0 1 1 1 0 EF-hand domain pair EF-hand_1 PF00036.32 OQS02193.1 - 0.032 13.8 0.0 0.095 12.3 0.0 1.8 1 0 0 1 1 1 0 EF hand WaaY PF06176.11 OQS02193.1 - 0.13 11.9 0.3 0.98 9.0 0.0 2.3 2 0 0 2 2 2 0 Lipopolysaccharide core biosynthesis protein (WaaY) Rpn3_C PF08375.11 OQS02194.1 - 4.5e-29 100.7 1.2 1.1e-28 99.4 1.2 1.7 1 0 0 1 1 1 1 Proteasome regulatory subunit C-terminal PCI PF01399.27 OQS02194.1 - 2.2e-21 76.3 0.0 1.5e-20 73.7 0.0 2.3 2 0 0 2 2 2 1 PCI domain SAC3_GANP PF03399.16 OQS02194.1 - 0.033 13.6 0.1 0.1 11.9 0.1 1.8 1 1 0 1 1 1 0 SAC3/GANP family Cytomega_UL84 PF06284.11 OQS02194.1 - 0.058 11.9 0.0 0.099 11.1 0.0 1.3 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein CODH_A_N PF18537.1 OQS02194.1 - 0.088 12.8 0.0 0.87 9.6 0.0 2.6 1 1 1 2 2 2 0 Carbon monoxide dehydrogenase subunit alpha N-terminal domain PhoU PF01895.19 OQS02194.1 - 1.5 9.4 5.9 1.4 9.4 0.3 3.3 3 1 0 3 3 3 0 PhoU domain Aminotran_5 PF00266.19 OQS02196.1 - 6e-23 81.4 0.0 9.2e-23 80.8 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Ion_trans PF00520.31 OQS02196.1 - 1.8e-08 33.9 6.2 2.8e-08 33.3 6.2 1.3 1 0 0 1 1 1 1 Ion transport protein DegT_DnrJ_EryC1 PF01041.17 OQS02196.1 - 7.7e-06 25.5 0.0 1.3e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.20 OQS02196.1 - 0.00098 17.8 0.0 0.0016 17.1 0.0 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme PKD_channel PF08016.12 OQS02196.1 - 0.031 13.0 6.1 0.066 11.9 6.1 1.6 1 0 0 1 1 1 0 Polycystin cation channel STE2 PF02116.15 OQS02197.1 - 0.0003 20.2 4.7 0.0003 20.2 4.7 1.4 2 0 0 2 2 2 1 Fungal pheromone mating factor STE2 GPCR Trep_Strep PF09605.10 OQS02197.1 - 0.035 14.1 3.5 0.15 12.0 3.0 1.9 1 1 1 2 2 2 0 Hypothetical bacterial integral membrane protein (Trep_Strep) Wzy_C_2 PF11846.8 OQS02197.1 - 0.04 13.8 0.3 0.55 10.1 0.0 2.1 1 1 1 2 2 2 0 Virulence factor membrane-bound polymerase, C-terminal Afaf PF15339.6 OQS02197.1 - 0.6 9.8 3.0 6.5 6.4 0.4 2.3 2 1 0 2 2 2 0 Acrosome formation-associated factor MTABC_N PF16185.5 OQS02197.1 - 0.95 8.9 9.3 1.8 8.0 5.9 2.1 2 0 0 2 2 2 0 Mitochondrial ABC-transporter N-terminal five TM region DUF373 PF04123.13 OQS02197.1 - 4.6 6.6 6.8 9.3 5.6 6.8 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF373) Ank_2 PF12796.7 OQS02198.1 - 5.9e-08 33.2 0.6 4.4e-05 24.0 0.0 3.1 1 1 2 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQS02198.1 - 2.5e-07 31.1 0.1 0.048 14.3 0.0 3.7 3 1 0 3 3 3 2 Ankyrin repeats (many copies) Adenylsucc_synt PF00709.21 OQS02198.1 - 0.00034 19.7 0.0 0.00043 19.3 0.0 1.2 1 0 0 1 1 1 1 Adenylosuccinate synthetase Ank_5 PF13857.6 OQS02198.1 - 0.0016 18.7 0.1 2.1 8.8 0.0 3.4 1 1 2 3 3 3 2 Ankyrin repeats (many copies) DUF5049 PF16468.5 OQS02198.1 - 0.12 12.3 0.1 0.85 9.6 0.0 2.3 2 1 1 3 3 3 0 Domain of unknown function (DUF5049) Pkinase PF00069.25 OQS02199.1 - 8e-53 179.5 0.2 4.7e-52 177.0 0.0 1.9 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQS02199.1 - 3.4e-51 174.0 0.0 5.2e-51 173.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Crystall PF00030.19 OQS02199.1 - 9e-06 25.8 0.2 0.0014 18.8 0.1 2.5 2 0 0 2 2 2 1 Beta/Gamma crystallin Kdo PF06293.14 OQS02199.1 - 0.00014 21.3 0.5 0.00024 20.6 0.1 1.5 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 OQS02199.1 - 0.0012 17.7 0.3 0.0072 15.2 0.1 1.9 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 OQS02199.1 - 0.0035 17.3 0.0 0.0058 16.6 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Crystall_3 PF08964.10 OQS02199.1 - 0.013 15.7 0.3 0.78 10.0 0.3 2.5 1 1 1 2 2 2 0 Beta/Gamma crystallin TNFR_16_TM PF18422.1 OQS02199.1 - 0.043 13.8 0.3 0.1 12.6 0.3 1.6 1 0 0 1 1 1 0 Tumor necrosis factor receptor member 16 trans-membrane domain Haspin_kinase PF12330.8 OQS02199.1 - 0.055 12.4 0.3 0.48 9.3 0.3 2.0 1 1 0 1 1 1 0 Haspin like kinase domain Inhibitor_I36 PF03995.13 OQS02199.1 - 0.08 12.9 3.9 0.5 10.3 2.7 2.8 1 1 1 2 2 2 0 Peptidase inhibitor family I36 Crystall PF00030.19 OQS02200.1 - 1.4e-05 25.2 0.0 1.9e-05 24.8 0.0 1.2 1 0 0 1 1 1 1 Beta/Gamma crystallin IL4_i_Ig PF18258.1 OQS02200.1 - 0.00051 20.2 0.1 0.0011 19.1 0.0 1.6 2 0 0 2 2 2 1 Interleukin-4 inducing immunoglobulin-binding domain Crystall_3 PF08964.10 OQS02200.1 - 0.027 14.6 0.1 2.4 8.4 0.0 2.1 1 1 1 2 2 2 0 Beta/Gamma crystallin Pkinase PF00069.25 OQS02201.1 - 6.9e-36 124.0 0.0 4.7e-35 121.2 0.0 1.9 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQS02201.1 - 8.4e-28 97.3 0.0 1.4e-27 96.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Ank_2 PF12796.7 OQS02201.1 - 2.5e-19 69.7 0.3 4.1e-08 33.7 0.1 2.5 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQS02201.1 - 2.6e-17 62.9 0.0 3.8e-05 24.2 0.0 4.3 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 OQS02201.1 - 5.8e-14 52.0 0.1 0.00013 22.1 0.0 4.4 4 0 0 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQS02201.1 - 1.4e-10 40.4 0.3 0.0067 16.8 0.0 5.7 6 0 0 6 6 6 2 Ankyrin repeat Ank PF00023.30 OQS02201.1 - 3.6e-10 39.8 0.3 0.035 14.6 0.0 5.6 5 0 0 5 5 5 3 Ankyrin repeat Kinase-like PF14531.6 OQS02201.1 - 0.0016 17.9 0.0 0.0027 17.1 0.0 1.4 1 0 0 1 1 1 1 Kinase-like ABC1 PF03109.16 OQS02201.1 - 0.024 14.8 0.0 0.087 13.0 0.0 1.9 2 0 0 2 2 2 0 ABC1 family Phage_lysis PF03245.13 OQS02202.1 - 0.0068 16.5 0.4 0.013 15.6 0.4 1.5 1 0 0 1 1 1 1 Bacteriophage Rz lysis protein DUF1951 PF09188.10 OQS02203.1 - 0.064 13.2 0.0 0.19 11.7 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF1951) Ubie_methyltran PF01209.18 OQS02204.1 - 5.1e-82 274.7 0.0 6.1e-82 274.4 0.0 1.0 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.6 OQS02204.1 - 7.7e-18 65.0 0.0 1.5e-16 60.9 0.0 2.7 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 OQS02204.1 - 1.7e-16 60.6 0.0 1.1e-15 58.1 0.0 2.2 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 OQS02204.1 - 1.1e-12 48.0 0.0 1.8e-12 47.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OQS02204.1 - 6.6e-09 36.4 0.0 1.3e-08 35.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OQS02204.1 - 6.6e-08 32.6 0.0 9.5e-08 32.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.15 OQS02204.1 - 0.076 12.9 0.0 0.22 11.3 0.0 1.7 1 1 0 1 1 1 0 Hypothetical methyltransferase Elicitin PF00964.17 OQS02206.1 - 0.019 15.1 1.1 0.41 10.8 0.5 2.2 1 1 1 2 2 2 0 Elicitin Ion_trans PF00520.31 OQS02207.1 - 4.3e-07 29.4 25.6 4.3e-07 29.4 25.6 4.9 4 1 0 5 5 5 2 Ion transport protein DUF962 PF06127.11 OQS02207.1 - 2.5 8.3 8.7 3 8.0 2.4 4.0 3 1 0 3 3 3 0 Protein of unknown function (DUF962) Ank_4 PF13637.6 OQS02208.1 - 6.5e-31 106.3 2.2 3.1e-11 43.6 0.1 2.6 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 OQS02208.1 - 8.9e-19 67.9 0.2 2e-09 37.9 0.0 2.1 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OQS02208.1 - 1.9e-16 59.9 0.2 1.8e-10 40.9 0.0 2.8 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 OQS02208.1 - 4.4e-16 58.5 3.5 6.4e-08 32.7 0.0 3.4 4 0 0 4 4 4 2 Ankyrin repeat Ank_3 PF13606.6 OQS02208.1 - 6.9e-16 56.7 2.2 1.2e-06 28.4 0.0 3.9 4 0 0 4 4 4 2 Ankyrin repeat IBR PF01485.21 OQS02209.1 - 1.4e-22 79.6 24.3 8.2e-16 58.0 3.2 4.2 3 1 1 4 4 4 2 IBR domain, a half RING-finger domain zf-C3HC4_2 PF13923.6 OQS02209.1 - 0.003 17.3 9.3 0.003 17.3 9.3 5.0 3 1 2 5 5 5 1 Zinc finger, C3HC4 type (RING finger) Phage_GPD PF05954.11 OQS02209.1 - 0.12 11.6 0.3 0.18 11.1 0.3 1.2 1 0 0 1 1 1 0 Phage late control gene D protein (GPD) Ank_2 PF12796.7 OQS02210.1 - 7.2e-52 173.9 32.3 2.8e-09 37.4 0.4 8.5 3 2 4 8 8 8 8 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQS02210.1 - 1.7e-41 140.0 30.4 3.4e-08 33.9 0.1 12.9 7 2 5 13 13 13 10 Ankyrin repeats (many copies) Ank_5 PF13857.6 OQS02210.1 - 1.2e-35 121.1 24.6 0.002 18.4 0.0 15.9 6 2 11 17 17 17 12 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQS02210.1 - 2.3e-26 88.9 22.8 0.22 12.2 0.4 17.3 17 2 3 20 20 19 6 Ankyrin repeat DUF3447 PF11929.8 OQS02210.1 - 4e-06 26.7 21.3 0.053 13.5 1.0 7.5 4 2 3 7 7 7 3 Domain of unknown function (DUF3447) Ank PF00023.30 OQS02210.1 - 2.8e-05 24.3 22.1 3.7 8.2 0.0 12.4 10 3 1 11 11 11 1 Ankyrin repeat DUF5049 PF16468.5 OQS02210.1 - 0.00092 19.1 17.6 2.8 7.9 0.0 8.9 10 2 2 12 12 12 1 Domain of unknown function (DUF5049) Phage_int_SAM_2 PF12834.7 OQS02210.1 - 0.023 15.4 6.8 21 5.9 0.0 4.7 5 0 0 5 5 5 0 Phage integrase, N-terminal BBS2_Mid PF14783.6 OQS02210.1 - 0.027 14.5 0.5 11 6.1 0.0 3.6 4 0 0 4 4 4 0 Ciliary BBSome complex subunit 2, middle region AAA_lid_9 PF17871.1 OQS02210.1 - 0.099 12.6 0.3 13 5.8 0.0 3.4 3 0 0 3 3 3 0 AAA lid domain CNOT1_HEAT PF16418.5 OQS02210.1 - 0.15 12.1 1.8 30 4.7 0.0 5.1 3 3 3 7 7 7 0 CCR4-NOT transcription complex subunit 1 HEAT repeat DDE_1 PF03184.19 OQS02211.1 - 0.00072 19.3 0.0 0.00083 19.0 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease Sporozoite_P67 PF05642.11 OQS02212.1 - 0.15 10.1 2.5 0.16 10.0 2.5 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DUF2431 PF10354.9 OQS02213.1 - 1.1e-41 142.9 0.0 1.6e-41 142.4 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF2431) BK_channel_a PF03493.18 OQS02214.1 - 1e-19 70.5 0.1 4.7e-19 68.4 0.1 2.2 1 1 0 1 1 1 1 Calcium-activated BK potassium channel alpha subunit Ion_trans_2 PF07885.16 OQS02214.1 - 1.4e-12 47.4 6.1 1.4e-12 47.4 6.1 2.5 2 0 0 2 2 2 1 Ion channel TrkA_N PF02254.18 OQS02214.1 - 2.1e-05 24.8 0.3 0.063 13.5 0.1 2.7 2 0 0 2 2 2 2 TrkA-N domain Castor_Poll_mid PF06241.12 OQS02214.1 - 0.14 12.2 0.0 0.45 10.5 0.0 1.9 1 0 0 1 1 1 0 Castor and Pollux, part of voltage-gated ion channel Humanin PF15040.6 OQS02214.1 - 0.2 11.1 1.6 0.58 9.6 1.6 1.8 1 0 0 1 1 1 0 Humanin family Lig_chan PF00060.26 OQS02214.1 - 0.3 10.9 2.6 0.51 10.2 1.0 2.1 2 0 0 2 2 2 0 Ligand-gated ion channel IBN_N PF03810.19 OQS02216.1 - 1.1e-07 31.6 0.2 5e-06 26.3 0.0 3.5 3 0 0 3 3 3 1 Importin-beta N-terminal domain Xpo1 PF08389.12 OQS02216.1 - 1.1e-05 25.5 9.3 0.0001 22.4 0.1 4.8 3 2 0 4 4 4 1 Exportin 1-like protein Cse1 PF08506.10 OQS02216.1 - 4.3e-05 22.5 2.2 9.7e-05 21.4 0.5 2.3 2 0 0 2 2 2 1 Cse1 HEAT PF02985.22 OQS02216.1 - 0.012 15.8 1.5 1.4 9.4 0.1 4.3 4 0 0 4 4 4 0 HEAT repeat HEAT_EZ PF13513.6 OQS02216.1 - 0.26 11.8 5.9 92 3.7 0.1 5.9 5 1 1 6 6 6 0 HEAT-like repeat DNA_pol_B_2 PF03175.13 OQS02217.1 - 3.7e-22 78.8 15.9 1.2e-21 77.2 12.9 2.6 1 1 1 2 2 2 1 DNA polymerase type B, organellar and viral Nucleic_acid_bd PF13820.6 OQS02217.1 - 0.099 12.5 0.3 2.9 7.7 0.0 2.5 2 0 0 2 2 2 0 Putative nucleic acid-binding region Pkinase PF00069.25 OQS02218.1 - 9.5e-73 244.8 0.0 1.1e-72 244.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQS02218.1 - 5.6e-29 101.2 0.0 1.5e-28 99.8 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 OQS02218.1 - 8e-06 25.4 0.0 1.2e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.11 OQS02218.1 - 0.029 13.5 0.4 0.057 12.5 0.3 1.4 1 1 0 1 1 1 0 Seadornavirus VP7 APH PF01636.23 OQS02218.1 - 0.045 13.7 0.2 0.11 12.3 0.1 1.6 1 1 1 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.14 OQS02218.1 - 0.072 12.4 0.3 0.18 11.1 0.2 1.7 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family WD40 PF00400.32 OQS02219.1 - 1e-09 38.9 0.6 0.00064 20.5 0.0 4.2 4 0 0 4 4 4 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OQS02219.1 - 6.4e-06 26.4 0.3 3.8 7.9 0.2 4.3 2 2 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 OQS02219.1 - 0.021 14.2 0.0 0.35 10.2 0.0 2.5 1 1 1 2 2 2 0 WD40-like domain N_NLPC_P60 PF12912.7 OQS02219.1 - 0.11 12.9 0.0 0.18 12.2 0.0 1.3 1 0 0 1 1 1 0 NLPC_P60 stabilising domain, N term DDE_3 PF13358.6 OQS02220.1 - 0.031 14.0 0.0 0.058 13.1 0.0 1.4 1 0 0 1 1 1 0 DDE superfamily endonuclease Anemone_cytotox PF06369.12 OQS02220.1 - 0.038 13.6 1.0 0.058 13.0 1.0 1.4 1 1 0 1 1 1 0 Sea anemone cytotoxic protein GTP_EFTU PF00009.27 OQS02221.1 - 9.2e-66 221.1 0.2 1.5e-65 220.4 0.2 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_II PF14492.6 OQS02221.1 - 4e-26 90.9 0.1 1.1e-25 89.6 0.1 1.8 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.24 OQS02221.1 - 2.1e-21 75.8 0.1 1.4e-20 73.1 0.0 2.3 2 0 0 2 2 2 1 Elongation factor G C-terminus EFG_IV PF03764.18 OQS02221.1 - 7.3e-16 58.0 0.0 2.1e-15 56.5 0.0 1.8 1 0 0 1 1 1 1 Elongation factor G, domain IV RF3_C PF16658.5 OQS02221.1 - 1.6e-08 34.4 0.0 4.6e-08 33.0 0.0 1.7 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain GTP_EFTU_D2 PF03144.25 OQS02221.1 - 1e-07 32.2 0.0 4.8e-07 30.1 0.0 2.2 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 OQS02221.1 - 0.0012 19.0 0.0 0.0027 17.8 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase GAT PF03127.14 OQS02221.1 - 0.0086 16.4 1.1 0.44 10.9 0.2 2.7 2 0 0 2 2 2 1 GAT domain ABC_tran PF00005.27 OQS02222.1 - 2.1e-09 38.0 0.0 3.2e-09 37.4 0.0 1.2 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 OQS02222.1 - 0.0016 17.9 0.1 0.0019 17.6 0.1 1.1 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain FKBP_N_2 PF18023.1 OQS02222.1 - 0.079 13.1 0.1 0.1 12.7 0.1 1.2 1 0 0 1 1 1 0 BDBT FKBP like N-terminal UMPH-1 PF05822.12 OQS02223.1 - 4.5e-80 268.7 0.0 7.8e-80 267.9 0.0 1.4 1 0 0 1 1 1 1 Pyrimidine 5'-nucleotidase (UMPH-1) Asp PF00026.23 OQS02223.1 - 8.2e-36 124.0 0.2 3.3e-35 122.0 0.2 1.8 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 OQS02223.1 - 7.4e-17 62.1 0.5 1.2e-14 55.0 0.5 2.4 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal HAD PF12710.7 OQS02223.1 - 0.027 14.9 0.0 0.058 13.8 0.0 1.6 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase MARVEL PF01284.23 OQS02224.1 - 2.1e-07 31.1 11.7 3.5e-07 30.4 11.7 1.4 1 1 0 1 1 1 1 Membrane-associating domain PYC_OADA PF02436.18 OQS02224.1 - 0.22 11.3 0.0 0.31 10.7 0.0 1.2 1 0 0 1 1 1 0 Conserved carboxylase domain DUF5304 PF17230.2 OQS02225.1 - 0.056 13.7 0.0 0.2 11.9 0.0 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF5304) SoxY PF13501.6 OQS02225.1 - 0.17 12.1 0.2 0.4 10.9 0.2 1.5 1 0 0 1 1 1 0 Sulfur oxidation protein SoxY Yip1 PF04893.17 OQS02226.1 - 0.012 15.4 1.7 0.012 15.4 1.7 2.8 4 0 0 4 4 4 0 Yip1 domain MHYT PF03707.16 OQS02226.1 - 0.56 10.4 4.2 1.9 8.7 0.2 3.2 3 0 0 3 3 3 0 Bacterial signalling protein N terminal repeat DUF948 PF06103.11 OQS02226.1 - 0.72 10.2 5.7 12 6.2 0.0 3.0 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) TBCC PF07986.12 OQS02227.1 - 1.8e-37 127.7 6.7 3.3e-37 126.9 6.7 1.5 1 0 0 1 1 1 1 Tubulin binding cofactor C CAP_C PF08603.11 OQS02227.1 - 3.1e-05 23.7 1.9 5.5e-05 22.8 1.9 1.4 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal HSDR_N_2 PF13588.6 OQS02227.1 - 0.065 13.2 0.0 0.64 10.0 0.0 2.5 2 1 0 2 2 2 0 Type I restriction enzyme R protein N terminus (HSDR_N) LRR_8 PF13855.6 OQS02229.1 - 4.5e-09 35.9 3.8 1.3e-06 28.0 4.6 3.1 3 0 0 3 3 3 1 Leucine rich repeat LRR_4 PF12799.7 OQS02229.1 - 1.9e-06 28.1 9.5 0.00016 22.0 3.1 4.4 3 2 1 4 4 4 2 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 OQS02229.1 - 6e-05 22.6 0.8 0.0003 20.3 0.9 2.1 1 1 0 1 1 1 1 Leucine-rich repeat LRR_6 PF13516.6 OQS02229.1 - 0.049 13.7 3.3 51 4.3 0.5 4.4 4 0 0 4 4 4 0 Leucine Rich repeat LRR_1 PF00560.33 OQS02229.1 - 0.39 11.4 2.5 96 4.2 0.4 4.2 2 1 1 3 3 3 0 Leucine Rich Repeat zf-RING_11 PF17123.5 OQS02230.1 - 0.0041 16.8 1.8 0.013 15.2 1.8 2.0 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4 PF00097.25 OQS02230.1 - 0.019 14.8 2.5 0.019 14.8 2.5 2.2 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 OQS02230.1 - 0.033 14.1 6.1 0.07 13.0 6.1 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 OQS02230.1 - 0.033 14.5 7.4 0.11 12.9 7.4 1.9 1 0 0 1 1 1 0 Ring finger domain zf-ANAPC11 PF12861.7 OQS02230.1 - 0.1 12.7 6.7 0.29 11.2 4.2 2.8 1 1 1 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_6 PF14835.6 OQS02230.1 - 0.36 10.7 2.9 0.74 9.7 2.9 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-C3HC4_2 PF13923.6 OQS02230.1 - 0.47 10.3 7.6 1.7 8.5 6.8 2.4 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OQS02230.1 - 0.7 10.0 5.3 1.9 8.6 5.3 1.8 1 0 0 1 1 1 0 RING-type zinc-finger zf-rbx1 PF12678.7 OQS02230.1 - 1.2 9.5 13.8 0.15 12.4 6.4 2.7 2 1 1 3 3 3 0 RING-H2 zinc finger domain zf-RING_5 PF14634.6 OQS02230.1 - 1.3 9.0 8.5 3.4 7.7 8.0 2.1 1 1 0 1 1 1 0 zinc-RING finger domain 5_3_exonuc_N PF02739.16 OQS02231.1 - 4.2e-12 46.2 0.0 5.9e-12 45.8 0.0 1.2 1 0 0 1 1 1 1 5'-3' exonuclease, N-terminal resolvase-like domain 5_3_exonuc PF01367.20 OQS02231.1 - 1.3e-11 45.0 0.0 2.2e-11 44.2 0.0 1.3 1 0 0 1 1 1 1 5'-3' exonuclease, C-terminal SAM fold NYN_YacP PF05991.11 OQS02231.1 - 0.15 12.0 0.1 0.34 10.8 0.1 1.5 1 0 0 1 1 1 0 YacP-like NYN domain AIRS PF00586.24 OQS02232.1 - 0.0035 17.9 0.1 0.0095 16.6 0.1 1.7 1 0 0 1 1 1 1 AIR synthase related protein, N-terminal domain UCH PF00443.29 OQS02233.1 - 1.1e-42 146.3 0.0 2.6e-42 145.1 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 OQS02233.1 - 6.7e-16 58.8 0.0 4e-12 46.4 0.0 2.5 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.23 OQS02233.1 - 7.7e-06 25.6 0.2 1.9e-05 24.4 0.2 1.6 1 0 0 1 1 1 1 Ubiquitin family TRP PF06011.12 OQS02234.1 - 4.4e-23 81.7 28.0 1e-22 80.5 26.3 2.3 2 1 0 2 2 2 1 Transient receptor potential (TRP) ion channel Claudin_2 PF13903.6 OQS02234.1 - 0.00027 20.7 15.4 0.057 13.2 0.9 5.1 5 0 0 5 5 5 2 PMP-22/EMP/MP20/Claudin tight junction Acyl_transf_2 PF02273.15 OQS02234.1 - 0.051 12.8 2.0 3.2 6.9 0.1 2.2 2 0 0 2 2 2 0 Acyl transferase TarH PF02203.15 OQS02234.1 - 0.82 9.6 3.4 4.9 7.0 0.0 3.7 4 0 0 4 4 4 0 Tar ligand binding domain homologue Lectin_N PF03954.14 OQS02234.1 - 2.8 7.7 10.0 0.18 11.6 0.1 3.6 2 2 2 4 4 4 0 Hepatic lectin, N-terminal domain AAA_7 PF12775.7 OQS02235.1 - 2.8e-05 23.7 0.2 0.00023 20.7 0.0 2.4 3 0 0 3 3 3 1 P-loop containing dynein motor region IstB_IS21 PF01695.17 OQS02235.1 - 0.0057 16.4 0.0 0.011 15.5 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_11 PF13086.6 OQS02235.1 - 0.0063 16.3 0.0 0.0089 15.8 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 OQS02235.1 - 0.012 15.8 0.0 0.049 13.9 0.0 2.0 1 1 0 1 1 1 0 AAA domain DUF2075 PF09848.9 OQS02235.1 - 0.016 14.5 0.3 0.63 9.2 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) RNase_H_2 PF13482.6 OQS02235.1 - 0.018 15.0 0.0 0.043 13.8 0.0 1.6 1 0 0 1 1 1 0 RNase_H superfamily AAA_25 PF13481.6 OQS02235.1 - 0.02 14.4 0.0 0.05 13.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain ResIII PF04851.15 OQS02235.1 - 0.022 14.8 0.0 0.068 13.2 0.0 1.8 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_16 PF13191.6 OQS02235.1 - 0.047 14.1 0.0 0.11 12.9 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain ATPase PF06745.13 OQS02235.1 - 0.083 12.2 0.0 0.2 11.0 0.0 1.6 1 0 0 1 1 1 0 KaiC AAA_14 PF13173.6 OQS02235.1 - 0.088 12.8 0.1 0.25 11.4 0.0 1.8 2 0 0 2 2 2 0 AAA domain Ubiquitin_2 PF14560.6 OQS02235.1 - 0.098 13.1 0.0 0.27 11.7 0.0 1.7 1 0 0 1 1 1 0 Ubiquitin-like domain AAA_5 PF07728.14 OQS02235.1 - 0.16 12.0 0.0 0.4 10.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Pkinase PF00069.25 OQS02236.1 - 7.4e-47 159.9 0.0 1.5e-46 158.9 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQS02236.1 - 2.9e-46 157.8 0.0 5.6e-46 156.9 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase TPR_2 PF07719.17 OQS02236.1 - 1.1e-13 50.2 3.2 2.4e-05 24.1 0.2 4.4 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_1 PF00515.28 OQS02236.1 - 1.1e-13 50.3 3.4 6.8e-06 25.7 0.0 3.3 3 0 0 3 3 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 OQS02236.1 - 9.7e-09 34.8 0.9 0.012 15.7 0.0 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 OQS02236.1 - 5.5e-08 33.0 2.3 0.0057 16.9 0.0 4.1 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.6 OQS02236.1 - 7e-08 32.5 0.0 2.8e-07 30.6 0.0 2.1 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_11 PF13414.6 OQS02236.1 - 6.2e-07 29.0 0.0 6.9e-05 22.4 0.0 3.0 2 1 0 2 2 2 1 TPR repeat TPR_17 PF13431.6 OQS02236.1 - 1.3e-06 28.4 0.0 0.025 15.0 0.0 4.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 OQS02236.1 - 1.4e-06 28.7 0.2 0.0021 18.7 0.0 4.4 3 1 2 5 5 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 OQS02236.1 - 4e-06 27.4 0.0 0.00017 22.2 0.0 2.8 2 1 1 3 3 2 2 Tetratricopeptide repeat Pkinase_fungal PF17667.1 OQS02236.1 - 0.00014 20.8 0.0 0.00027 19.8 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase TPR_19 PF14559.6 OQS02236.1 - 0.00092 19.7 0.0 0.0046 17.5 0.0 2.2 1 0 0 1 1 1 1 Tetratricopeptide repeat Kinase-like PF14531.6 OQS02236.1 - 0.019 14.3 0.0 0.042 13.2 0.0 1.5 1 0 0 1 1 1 0 Kinase-like Kdo PF06293.14 OQS02236.1 - 0.043 13.2 0.0 0.13 11.6 0.0 1.8 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family stn_TNFRSF12A PF12191.8 OQS02236.1 - 0.06 13.6 0.1 0.13 12.5 0.1 1.4 1 0 0 1 1 1 0 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain FTA2 PF13095.6 OQS02236.1 - 0.064 12.9 0.0 0.61 9.7 0.0 2.4 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 TPR_7 PF13176.6 OQS02236.1 - 0.079 13.0 0.1 3 8.1 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat APH PF01636.23 OQS02236.1 - 0.11 12.4 0.1 2.4 8.0 0.0 2.4 2 0 0 2 2 2 0 Phosphotransferase enzyme family TPR_10 PF13374.6 OQS02236.1 - 0.29 11.1 8.7 12 5.9 0.0 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat LRR_8 PF13855.6 OQS02236.1 - 0.78 9.6 13.7 0.18 11.6 4.7 3.6 3 0 0 3 3 3 0 Leucine rich repeat SpoIIE PF07228.12 OQS02237.1 - 2.3e-11 44.0 0.0 8.6e-11 42.1 0.0 1.8 1 1 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.6 OQS02237.1 - 0.00012 21.8 0.0 0.00028 20.6 0.0 1.5 1 1 0 1 1 1 1 Protein phosphatase 2C PP2C PF00481.21 OQS02237.1 - 0.00059 19.5 0.1 0.29 10.7 0.0 2.2 2 0 0 2 2 2 2 Protein phosphatase 2C NUDIX PF00293.28 OQS02238.1 - 2.7e-09 37.1 1.0 1.2e-07 31.9 0.9 2.8 1 1 0 1 1 1 1 NUDIX domain Fe-S_biosyn PF01521.20 OQS02239.1 - 1.4e-17 63.9 0.0 1.6e-17 63.7 0.0 1.0 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis OB_NTP_bind PF07717.16 OQS02240.1 - 1.9e-23 82.6 0.0 3.7e-23 81.7 0.0 1.5 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.23 OQS02240.1 - 3.1e-22 78.9 0.9 1.8e-21 76.4 0.0 2.5 2 0 0 2 2 2 1 Helicase associated domain (HA2) Helicase_C PF00271.31 OQS02240.1 - 7.2e-14 52.1 0.0 2.3e-13 50.4 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain S1 PF00575.23 OQS02240.1 - 1.8e-11 44.2 0.3 4.3e-11 43.0 0.3 1.6 1 0 0 1 1 1 1 S1 RNA binding domain DEAD PF00270.29 OQS02240.1 - 3.3e-07 30.3 0.2 7.3e-07 29.1 0.2 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 OQS02240.1 - 2.6e-06 27.8 0.0 7.3e-06 26.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 OQS02240.1 - 0.00054 20.3 0.2 0.0012 19.2 0.2 1.5 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 OQS02240.1 - 0.0012 17.9 0.0 0.0034 16.5 0.0 1.7 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_30 PF13604.6 OQS02240.1 - 0.0025 17.6 0.1 0.0052 16.5 0.1 1.4 1 0 0 1 1 1 1 AAA domain DUF2075 PF09848.9 OQS02240.1 - 0.0045 16.3 0.0 0.0089 15.3 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_14 PF13173.6 OQS02240.1 - 0.0051 16.9 0.2 0.091 12.8 0.2 2.6 1 1 0 1 1 1 1 AAA domain Microtub_bd PF16796.5 OQS02240.1 - 0.008 16.1 0.1 0.41 10.6 0.0 2.5 2 0 0 2 2 2 1 Microtubule binding PhoH PF02562.16 OQS02240.1 - 0.0096 15.4 0.3 0.027 13.9 0.1 1.8 2 0 0 2 2 2 1 PhoH-like protein ABC_tran PF00005.27 OQS02240.1 - 0.013 16.0 0.9 1.3 9.5 0.1 3.2 2 1 0 3 3 3 0 ABC transporter ResIII PF04851.15 OQS02240.1 - 0.027 14.5 0.2 1.8 8.5 0.1 2.5 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit AAA PF00004.29 OQS02240.1 - 0.038 14.4 1.5 2.2 8.7 0.4 3.2 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.17 OQS02240.1 - 0.049 13.4 0.0 9.8 5.9 0.0 2.5 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_7 PF12775.7 OQS02240.1 - 0.072 12.6 0.0 0.14 11.7 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region Flavi_DEAD PF07652.14 OQS02240.1 - 0.082 12.9 0.1 0.16 11.9 0.1 1.4 1 0 0 1 1 1 0 Flavivirus DEAD domain NB-ARC PF00931.22 OQS02240.1 - 0.13 11.4 0.0 0.26 10.4 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain Pkinase_Tyr PF07714.17 OQS02241.1 - 9e-27 94.0 0.1 1.2e-26 93.6 0.1 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OQS02241.1 - 6.7e-21 74.8 0.1 8.7e-21 74.5 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 OQS02241.1 - 0.006 16.0 0.1 0.0076 15.6 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family KIND PF16474.5 OQS02241.1 - 0.069 13.0 0.0 0.099 12.5 0.0 1.2 1 0 0 1 1 1 0 Kinase non-catalytic C-lobe domain Phage_connect_1 PF05135.13 OQS02242.1 - 0.02 15.4 0.1 0.029 14.9 0.1 1.3 1 0 0 1 1 1 0 Phage gp6-like head-tail connector protein LIP PF03583.14 OQS02242.1 - 0.14 11.4 0.0 0.17 11.2 0.0 1.0 1 0 0 1 1 1 0 Secretory lipase Spo0A_C PF08769.11 OQS02242.1 - 0.15 12.2 0.1 0.2 11.7 0.1 1.2 1 0 0 1 1 1 0 Sporulation initiation factor Spo0A C terminal LRR_6 PF13516.6 OQS02243.1 - 3.2e-07 29.9 11.2 0.068 13.3 1.5 4.9 5 0 0 5 5 5 3 Leucine Rich repeat LRR_1 PF00560.33 OQS02243.1 - 0.0079 16.6 8.6 23 6.1 1.0 5.7 6 0 0 6 6 6 1 Leucine Rich Repeat LRR_4 PF12799.7 OQS02243.1 - 2.6 8.6 20.6 5.4 7.6 6.8 4.4 3 2 2 5 5 5 0 Leucine Rich repeats (2 copies) SpoIIE PF07228.12 OQS02244.1 - 0.00091 19.2 0.0 0.005 16.8 0.0 2.0 1 1 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) Gal_Lectin PF02140.18 OQS02244.1 - 0.16 12.4 2.9 0.44 11.0 2.9 1.7 1 0 0 1 1 1 0 Galactose binding lectin domain PNP_UDP_1 PF01048.20 OQS02245.1 - 1.3e-39 135.8 0.2 2.7e-39 134.8 0.2 1.5 1 0 0 1 1 1 1 Phosphorylase superfamily GRIP PF01465.20 OQS02245.1 - 2.9e-10 39.9 0.0 5.9e-10 38.9 0.0 1.5 1 0 0 1 1 1 1 GRIP domain CDI PF02234.19 OQS02245.1 - 5.9 7.2 6.9 7 6.9 0.6 3.8 4 0 0 4 4 4 0 Cyclin-dependent kinase inhibitor Tam41_Mmp37 PF09139.11 OQS02246.1 - 2.1e-96 323.2 0.5 4.2e-96 322.2 0.5 1.4 1 1 0 1 1 1 1 Phosphatidate cytidylyltransferase, mitochondrial T4_tail_cap PF11091.8 OQS02246.1 - 0.0086 15.0 0.0 0.04 12.8 0.0 1.8 2 0 0 2 2 2 1 Tail-tube assembly protein Ank PF00023.30 OQS02247.1 - 4e-51 169.3 15.3 2.3e-09 37.3 0.6 7.2 7 0 0 7 7 7 7 Ankyrin repeat Ank_4 PF13637.6 OQS02247.1 - 3.5e-43 145.4 9.7 3.8e-12 46.5 0.1 5.6 2 2 4 6 6 6 6 Ankyrin repeats (many copies) Ank_2 PF12796.7 OQS02247.1 - 4.2e-43 145.8 5.9 4.8e-17 62.3 0.2 4.9 3 2 0 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OQS02247.1 - 4.5e-38 124.9 4.4 8.3e-06 25.8 0.1 7.2 6 1 1 7 7 7 6 Ankyrin repeat Ank_5 PF13857.6 OQS02247.1 - 2.6e-24 85.0 8.6 4.5e-06 26.8 0.0 6.4 5 2 2 7 7 7 5 Ankyrin repeats (many copies) DUF2278 PF10042.9 OQS02247.1 - 0.0091 16.0 0.3 1 9.3 0.1 2.7 1 1 2 3 3 3 1 Uncharacterized conserved protein (DUF2278) VWA_3_C PF18571.1 OQS02247.1 - 0.06 13.2 4.8 23 5.0 0.1 4.5 4 0 0 4 4 4 0 von Willebrand factor type A C-terminal domain DUF5535 PF17687.1 OQS02247.1 - 0.16 12.1 0.0 81 3.4 0.0 3.8 2 1 2 4 4 4 0 Family of unknown function (DUF5535) Amidohydro_1 PF01979.20 OQS02247.1 - 0.41 9.9 10.7 9.7 5.4 0.4 3.8 1 1 2 4 4 4 0 Amidohydrolase family FAD_binding_6 PF00970.24 OQS02248.1 - 4.9e-24 84.6 0.0 1.1e-23 83.4 0.0 1.6 2 0 0 2 2 2 1 Oxidoreductase FAD-binding domain Cyt-b5 PF00173.28 OQS02248.1 - 3e-19 68.9 0.0 5.5e-19 68.1 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain NAD_binding_1 PF00175.21 OQS02248.1 - 7.4e-17 62.0 0.0 1.2e-16 61.3 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 OQS02248.1 - 0.00025 21.2 0.0 0.0013 18.9 0.0 2.0 2 0 0 2 2 2 1 Ferric reductase NAD binding domain FAD_binding_9 PF08021.11 OQS02248.1 - 0.056 13.7 0.0 0.089 13.0 0.0 1.3 1 0 0 1 1 1 0 Siderophore-interacting FAD-binding domain Ank_2 PF12796.7 OQS02249.1 - 1.1e-22 80.4 11.8 2.7e-07 31.1 0.1 5.0 2 2 4 6 6 6 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQS02249.1 - 3.2e-15 56.3 11.5 2e-05 25.0 1.0 6.4 4 2 2 6 6 6 6 Ankyrin repeats (many copies) Ank_5 PF13857.6 OQS02249.1 - 6.7e-12 45.4 9.5 0.67 10.4 0.0 7.7 2 2 6 8 8 8 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQS02249.1 - 6.7e-11 41.4 10.8 6.8 7.6 0.0 8.9 7 2 3 10 10 10 3 Ankyrin repeat Sushi_2 PF09014.10 OQS02249.1 - 0.13 12.2 0.0 0.4 10.6 0.0 1.8 1 0 0 1 1 1 0 Beta-2-glycoprotein-1 fifth domain Ank PF00023.30 OQS02249.1 - 0.21 12.1 6.3 81 3.9 0.0 6.0 3 2 0 3 3 3 0 Ankyrin repeat Acetyltransf_1 PF00583.25 OQS02250.1 - 8.8e-05 22.7 0.0 0.00044 20.5 0.0 2.0 1 1 1 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 OQS02250.1 - 0.0012 19.2 0.0 0.0094 16.4 0.0 2.1 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 OQS02250.1 - 0.069 13.2 0.0 0.16 12.1 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain FR47 PF08445.10 OQS02250.1 - 0.12 12.4 0.0 0.24 11.4 0.0 1.5 1 0 0 1 1 1 0 FR47-like protein WD40 PF00400.32 OQS02252.1 - 1.2e-26 92.5 5.2 9.3e-05 23.1 0.2 7.5 7 0 0 7 7 7 4 WD domain, G-beta repeat EB1 PF03271.17 OQS02252.1 - 2.7e-14 53.1 1.1 7.2e-14 51.8 1.1 1.7 1 0 0 1 1 1 1 EB1-like C-terminal motif ANAPC4_WD40 PF12894.7 OQS02252.1 - 5e-12 46.0 0.1 0.0079 16.5 0.0 5.9 1 1 4 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain CH PF00307.31 OQS02252.1 - 6e-07 29.6 0.1 1.4e-06 28.4 0.1 1.5 1 0 0 1 1 1 1 Calponin homology (CH) domain Ge1_WD40 PF16529.5 OQS02252.1 - 5.3e-06 25.6 0.3 0.0095 14.9 0.1 3.6 2 1 0 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 OQS02252.1 - 0.0029 17.5 0.1 0.61 9.9 0.0 2.8 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A Gmad1 PF10647.9 OQS02252.1 - 0.026 14.3 0.1 0.055 13.2 0.1 1.5 1 0 0 1 1 1 0 Lipoprotein LpqB beta-propeller domain Nup160 PF11715.8 OQS02252.1 - 0.03 13.0 0.1 0.59 8.7 0.1 2.4 1 1 1 2 2 2 0 Nucleoporin Nup120/160 CH_2 PF06294.11 OQS02252.1 - 0.05 13.7 0.0 0.11 12.6 0.0 1.6 1 0 0 1 1 1 0 CH-like domain in sperm protein APG6_N PF17675.1 OQS02252.1 - 0.1 13.1 1.0 0.39 11.2 0.3 2.0 2 0 0 2 2 2 0 Apg6 coiled-coil region Rubis-subs-bind PF09273.11 OQS02253.1 - 1.4e-39 135.7 10.1 1.1e-20 74.7 2.8 2.3 2 0 0 2 2 2 2 Rubisco LSMT substrate-binding SET PF00856.28 OQS02253.1 - 2.1e-06 28.3 0.0 0.022 15.1 0.0 2.4 2 0 0 2 2 2 2 SET domain DUF4965 PF16335.5 OQS02253.1 - 0.028 14.1 0.3 1.4 8.6 0.0 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4965) Ish1 PF10281.9 OQS02253.1 - 0.37 11.1 1.5 12 6.3 0.1 3.0 2 0 0 2 2 2 0 Putative stress-responsive nuclear envelope protein peroxidase PF00141.23 OQS02254.1 - 2.2e-45 155.1 0.0 3.5e-45 154.5 0.0 1.3 1 0 0 1 1 1 1 Peroxidase Chitin_bind_1 PF00187.19 OQS02255.1 - 1.8e-10 41.1 39.9 3.9e-06 27.2 15.7 3.6 4 0 0 4 4 4 2 Chitin recognition protein Ricin_B_lectin PF00652.22 OQS02257.1 - 3.1e-27 95.3 30.4 3.2e-13 50.0 6.6 3.3 1 1 1 3 3 3 3 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.6 OQS02257.1 - 1.2e-12 48.4 19.8 3.4e-05 24.5 0.9 4.7 2 1 3 5 5 5 3 Ricin-type beta-trefoil lectin domain-like DUF1102 PF06510.11 OQS02257.1 - 0.014 15.5 2.1 0.052 13.7 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1102) SOXp PF12336.8 OQS02257.1 - 0.49 11.5 5.5 4.3 8.5 0.4 2.5 2 0 0 2 2 2 0 SOX transcription factor Glyco_hydro_19 PF00182.19 OQS02258.1 - 2.2e-23 83.4 22.9 5.7e-11 42.8 1.4 4.1 2 1 2 4 4 4 3 Chitinase class I Chitin_bind_1 PF00187.19 OQS02258.1 - 5.7e-11 42.7 44.8 9.8e-06 25.9 17.6 2.9 2 0 0 2 2 2 2 Chitin recognition protein HTH_Tnp_Tc3_1 PF11427.8 OQS02259.1 - 0.022 14.6 0.0 0.036 13.9 0.0 1.4 1 0 0 1 1 1 0 Tc3 transposase DDE_3 PF13358.6 OQS02260.1 - 0.092 12.5 0.0 0.13 12.0 0.0 1.2 1 0 0 1 1 1 0 DDE superfamily endonuclease ADK_lid PF05191.14 OQS02260.1 - 0.22 11.5 2.8 4.3 7.4 0.5 2.5 3 0 0 3 3 3 0 Adenylate kinase, active site lid APG9 PF04109.16 OQS02261.1 - 3.9e-144 481.2 9.3 5.2e-144 480.8 9.3 1.1 1 0 0 1 1 1 1 Autophagy protein Apg9 Kazal_1 PF00050.21 OQS02261.1 - 1.2e-06 28.4 6.2 4.3e-06 26.6 3.1 2.4 2 0 0 2 2 2 1 Kazal-type serine protease inhibitor domain Kazal_2 PF07648.15 OQS02261.1 - 2.3e-06 27.6 4.8 5.6e-06 26.4 4.8 1.7 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain DNA_topoisoIV PF00521.20 OQS02262.1 - 1.9e-05 23.7 0.1 3e-05 23.1 0.1 1.2 1 0 0 1 1 1 1 DNA gyrase/topoisomerase IV, subunit A Pkinase PF00069.25 OQS02263.1 - 6.9e-39 133.8 0.0 8.9e-39 133.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQS02263.1 - 1e-34 120.0 0.0 1.4e-34 119.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 OQS02263.1 - 0.00055 19.0 0.0 0.00093 18.2 0.0 1.3 1 0 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 OQS02263.1 - 0.18 10.5 0.0 0.26 10.0 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Mito_carr PF00153.27 OQS02264.1 - 2.3e-54 181.3 6.5 4.9e-18 64.8 0.0 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein Presenilin PF01080.17 OQS02264.1 - 0.38 9.5 9.6 0.58 8.9 9.6 1.2 1 0 0 1 1 1 0 Presenilin Macoilin PF09726.9 OQS02264.1 - 2.7 6.4 12.5 3.4 6.1 12.5 1.1 1 0 0 1 1 1 0 Macoilin family RSRP PF17069.5 OQS02264.1 - 3.7 7.0 48.4 0.098 12.2 34.2 2.2 2 0 0 2 2 2 0 Arginine/Serine-Rich protein 1 Ank_2 PF12796.7 OQS02265.1 - 9.8e-39 131.8 1.5 6.9e-16 58.6 0.0 4.4 3 1 1 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.30 OQS02265.1 - 1.3e-31 107.7 12.7 4.6e-05 23.7 0.0 10.0 10 0 0 10 10 10 7 Ankyrin repeat Ank_4 PF13637.6 OQS02265.1 - 5.4e-26 90.6 0.3 1.3e-06 28.9 0.0 7.6 5 2 2 8 8 8 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQS02265.1 - 1.8e-22 77.0 0.5 0.0006 20.1 0.0 8.9 9 0 0 9 9 9 4 Ankyrin repeat Ank_5 PF13857.6 OQS02265.1 - 1.6e-21 76.1 0.5 2.1e-06 27.9 0.0 6.9 4 3 3 7 7 7 4 Ankyrin repeats (many copies) Arg_repressor PF01316.21 OQS02265.1 - 0.0043 16.8 5.4 86 3.0 0.0 7.3 9 0 0 9 9 9 0 Arginine repressor, DNA binding domain Ank_5 PF13857.6 OQS02268.1 - 1.1e-05 25.6 0.0 4.3e-05 23.7 0.0 2.0 1 1 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 OQS02268.1 - 0.015 15.9 0.0 0.034 14.7 0.0 1.7 1 1 0 1 1 1 0 Ankyrin repeats (3 copies) Ank PF00023.30 OQS02268.1 - 0.017 15.6 0.1 0.052 14.0 0.0 1.9 2 1 0 2 2 2 0 Ankyrin repeat Ank_3 PF13606.6 OQS02268.1 - 0.1 13.2 0.0 10 7.1 0.0 3.1 2 1 1 3 3 3 0 Ankyrin repeat MT PF12777.7 OQS02269.1 - 1.5e-08 34.1 0.1 1.7e-08 33.9 0.1 1.0 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor CAP59_mtransfer PF11735.8 OQS02270.1 - 7.4e-59 199.3 0.0 9.7e-59 199.0 0.0 1.1 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 Glyco_tranf_2_4 PF13704.6 OQS02270.1 - 0.12 12.9 0.0 0.33 11.5 0.0 1.8 1 0 0 1 1 1 0 Glycosyl transferase family 2 Pkinase PF00069.25 OQS02271.1 - 2.6e-35 122.1 0.0 4.3e-35 121.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQS02271.1 - 2.3e-30 105.8 0.0 4e-29 101.7 0.0 2.1 1 1 1 2 2 2 1 Protein tyrosine kinase Haspin_kinase PF12330.8 OQS02271.1 - 0.012 14.6 0.0 0.019 13.9 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Rax2 PF12768.7 OQS02271.1 - 0.11 12.0 0.0 0.18 11.3 0.0 1.3 1 0 0 1 1 1 0 Cortical protein marker for cell polarity SIT PF15330.6 OQS02271.1 - 0.15 12.6 0.0 0.27 11.7 0.0 1.4 1 0 0 1 1 1 0 SHP2-interacting transmembrane adaptor protein, SIT RAMP4 PF06624.12 OQS02271.1 - 1.7 8.8 3.1 1.8 8.7 0.3 2.1 2 0 0 2 2 2 0 Ribosome associated membrane protein RAMP4 Pkinase_Tyr PF07714.17 OQS02272.1 - 2.1e-45 155.0 0.0 3.1e-45 154.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OQS02272.1 - 3.9e-45 154.3 0.0 6.5e-45 153.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain TMEM51 PF15345.6 OQS02272.1 - 0.0074 16.2 0.0 0.012 15.5 0.0 1.2 1 0 0 1 1 1 1 Transmembrane protein 51 PIRT PF15099.6 OQS02272.1 - 0.032 13.8 0.0 0.072 12.7 0.0 1.5 1 0 0 1 1 1 0 Phosphoinositide-interacting protein family Haspin_kinase PF12330.8 OQS02272.1 - 0.076 11.9 0.0 0.13 11.1 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain DIOX_N PF14226.6 OQS02272.1 - 0.081 13.7 0.0 0.17 12.6 0.0 1.4 1 0 0 1 1 1 0 non-haem dioxygenase in morphine synthesis N-terminal EphA2_TM PF14575.6 OQS02272.1 - 0.083 13.8 0.0 0.2 12.6 0.0 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain NICE-3 PF07406.11 OQS02272.1 - 0.14 12.1 0.1 0.25 11.3 0.1 1.3 1 0 0 1 1 1 0 NICE-3 protein Adeno_E3_CR2 PF02439.15 OQS02272.1 - 0.2 11.5 3.1 0.41 10.4 3.1 1.5 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 adh_short PF00106.25 OQS02273.1 - 2e-34 118.8 0.0 5.9e-34 117.2 0.0 1.6 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 OQS02273.1 - 6.8e-28 97.8 0.0 8.9e-28 97.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OQS02273.1 - 2.4e-06 27.6 0.0 0.0011 18.9 0.0 2.2 2 0 0 2 2 2 2 KR domain Shikimate_DH PF01488.20 OQS02273.1 - 0.00039 20.5 0.0 0.00079 19.5 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase 3HCDH_N PF02737.18 OQS02273.1 - 0.0051 16.7 0.0 0.0094 15.8 0.0 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Peptidase_M24 PF00557.24 OQS02274.1 - 1.1e-39 136.3 0.0 1.4e-39 136.0 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 DUF4645 PF15488.6 OQS02275.1 - 0.044 13.2 0.3 0.1 12.1 0.3 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4645) Glyco_hydro_36N PF16875.5 OQS02275.1 - 0.2 11.2 3.2 0.29 10.7 0.8 2.2 2 0 0 2 2 2 0 Glycosyl hydrolase family 36 N-terminal domain Rnk_N PF14760.6 OQS02275.1 - 1.1 9.8 4.5 27 5.4 1.0 4.2 2 0 0 2 2 2 0 Rnk N-terminus TSC22 PF01166.18 OQS02275.1 - 1.8 8.9 0.0 1.8 8.9 0.0 9.8 9 2 2 11 11 11 0 TSC-22/dip/bun family Peptidase_M24 PF00557.24 OQS02276.1 - 2.2e-41 141.9 0.1 3.1e-41 141.4 0.1 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 Rtf2 PF04641.12 OQS02276.1 - 0.0074 15.7 1.7 0.013 14.9 1.7 1.3 1 0 0 1 1 1 1 Rtf2 RING-finger CASP_C PF08172.12 OQS02276.1 - 0.2 11.0 0.1 0.2 11.0 0.1 1.7 2 0 0 2 2 2 0 CASP C terminal AP3D1 PF06375.11 OQS02276.1 - 6 7.1 8.3 11 6.3 8.3 1.3 1 0 0 1 1 1 0 AP-3 complex subunit delta-1 SPT6_acidic PF14632.6 OQS02276.1 - 6.3 7.5 11.5 0.53 10.9 6.1 2.0 3 0 0 3 3 3 0 Acidic N-terminal SPT6 Lipase3_N PF03893.16 OQS02279.1 - 0.05 13.6 0.1 0.16 12.0 0.0 2.0 2 0 0 2 2 2 0 Lipase 3 N-terminal region Glyco_trans_A_1 PF09318.10 OQS02279.1 - 0.06 13.1 0.0 0.12 12.0 0.0 1.5 1 0 0 1 1 1 0 Glycosyl transferase 1 domain A Nudix_hydro PF18290.1 OQS02279.1 - 0.067 13.2 0.2 0.95 9.5 0.2 2.3 2 0 0 2 2 2 0 Nudix hydrolase domain TLD PF07534.16 OQS02280.1 - 2e-30 105.8 0.1 3.8e-30 104.9 0.1 1.5 1 0 0 1 1 1 1 TLD RhoGAP PF00620.27 OQS02280.1 - 5.2e-17 62.1 0.0 1.2e-16 61.0 0.0 1.6 1 0 0 1 1 1 1 RhoGAP domain SET PF00856.28 OQS02280.1 - 1.8e-14 54.5 0.4 1.8e-14 54.5 0.4 3.5 3 2 0 3 3 3 1 SET domain RUN PF02759.19 OQS02280.1 - 2.1e-13 50.4 0.6 6.1e-13 48.9 0.6 1.9 1 0 0 1 1 1 1 RUN domain ELMO_CED12 PF04727.13 OQS02280.1 - 1.2e-08 35.2 1.0 1.2e-08 35.2 1.0 2.1 2 1 0 2 2 2 1 ELMO/CED-12 family AWS PF17907.1 OQS02280.1 - 8.5e-08 32.1 3.8 4.2e-07 29.9 3.8 2.3 1 0 0 1 1 1 1 AWS domain PHD PF00628.29 OQS02280.1 - 2.7e-05 23.9 11.0 2.7e-05 23.9 11.0 2.8 2 0 0 2 2 2 1 PHD-finger TPX2_importin PF12214.8 OQS02280.1 - 0.0019 18.4 14.4 0.0019 18.4 14.4 4.6 4 1 0 4 4 4 2 Cell cycle regulated microtubule associated protein PHD_2 PF13831.6 OQS02280.1 - 0.87 9.2 9.1 0.26 10.9 5.6 2.1 2 0 0 2 2 2 0 PHD-finger RAI1 PF08652.11 OQS02282.1 - 7.7e-18 64.5 0.0 1.2e-17 63.8 0.0 1.4 1 0 0 1 1 1 1 RAI1 like PD-(D/E)XK nuclease Acetyltransf_1 PF00583.25 OQS02283.1 - 5.6e-05 23.4 0.0 7.7e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 OQS02283.1 - 0.073 13.5 0.0 0.11 13.0 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain zf-HIT PF04438.16 OQS02283.1 - 0.13 12.2 0.9 0.24 11.3 0.9 1.4 1 0 0 1 1 1 0 HIT zinc finger Elf1 PF05129.13 OQS02283.1 - 0.33 11.0 1.5 0.82 9.8 1.5 1.6 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like NADH-G_4Fe-4S_3 PF10588.9 OQS02283.1 - 0.61 9.7 3.7 0.88 9.2 2.5 1.9 1 1 0 1 1 1 0 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region PKcGMP_CC PF16808.5 OQS02284.1 - 8.6e-06 25.5 25.8 0.038 13.8 0.0 8.4 9 0 0 9 9 9 3 Coiled-coil N-terminus of cGMP-dependent protein kinase HMMR_N PF15905.5 OQS02284.1 - 0.0015 18.1 32.3 0.0015 18.1 32.3 4.3 2 1 3 5 5 5 2 Hyaluronan mediated motility receptor N-terminal DUF2935 PF11155.8 OQS02284.1 - 2.2 8.6 21.5 6.4 7.1 2.3 5.6 2 2 1 3 3 3 0 Domain of unknown function (DUF2935) DUF641 PF04859.12 OQS02284.1 - 3 8.2 70.6 1.5 9.2 3.7 9.5 3 2 5 8 8 8 0 Plant protein of unknown function (DUF641) TMF_TATA_bd PF12325.8 OQS02284.1 - 6 7.1 78.5 0.098 12.9 2.5 8.5 3 2 8 11 11 11 0 TATA element modulatory factor 1 TATA binding IF4E PF01652.18 OQS02285.1 - 6.9e-55 185.2 0.4 1.6e-54 184.0 0.4 1.7 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Proteasome PF00227.26 OQS02285.1 - 1.1e-46 158.8 0.5 8.9e-46 155.8 0.8 2.2 2 0 0 2 2 2 1 Proteasome subunit PRKCSH-like PF12999.7 OQS02285.1 - 4.5e-12 46.1 3.1 4.5e-12 46.1 3.1 4.1 3 1 1 4 4 4 1 Glucosidase II beta subunit-like Beta-Casp PF10996.8 OQS02285.1 - 7.5e-06 26.2 0.0 5.4e-05 23.4 0.0 2.5 2 0 0 2 2 2 1 Beta-Casp domain Lactamase_B_6 PF16661.5 OQS02285.1 - 3.1e-05 23.5 0.1 0.00015 21.3 0.0 2.2 2 1 0 2 2 2 1 Metallo-beta-lactamase superfamily domain DUF4200 PF13863.6 OQS02285.1 - 0.002 18.5 6.3 0.002 18.5 6.3 4.4 1 1 2 4 4 4 2 Domain of unknown function (DUF4200) DUF3573 PF12097.8 OQS02285.1 - 0.63 8.8 6.1 1.2 7.8 6.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) Bacillus_HBL PF05791.11 OQS02285.1 - 5 6.9 21.3 3.4 7.5 0.1 4.1 1 1 3 5 5 5 0 Bacillus haemolytic enterotoxin (HBL) UPF0242 PF06785.11 OQS02285.1 - 8.7 6.4 49.5 0.032 14.3 20.4 3.6 2 1 2 4 4 4 0 Uncharacterised protein family (UPF0242) N-terminus Tub PF01167.18 OQS02287.1 - 8.8e-29 101.0 0.0 1.4e-28 100.3 0.0 1.2 1 0 0 1 1 1 1 Tub family HEAT PF02985.22 OQS02288.1 - 0.0018 18.4 0.5 0.7 10.3 0.1 3.5 3 0 0 3 3 3 2 HEAT repeat RACo_linker PF17650.1 OQS02288.1 - 0.13 12.2 3.0 2 8.3 0.1 3.1 3 0 0 3 3 3 0 RACo linker region Pkinase PF00069.25 OQS02289.1 - 7e-128 425.5 0.0 2.4e-59 200.9 0.0 3.5 4 0 0 4 4 4 3 Protein kinase domain Pkinase_Tyr PF07714.17 OQS02289.1 - 6.6e-111 369.7 0.0 6.5e-37 127.2 0.0 3.2 3 0 0 3 3 3 3 Protein tyrosine kinase EF-hand_7 PF13499.6 OQS02289.1 - 6.6e-18 64.9 0.5 6.9e-07 29.6 0.0 4.4 4 0 0 4 4 4 2 EF-hand domain pair EF-hand_6 PF13405.6 OQS02289.1 - 3.6e-13 48.3 2.0 0.075 13.0 0.0 6.5 6 0 0 6 6 6 2 EF-hand domain EF-hand_1 PF00036.32 OQS02289.1 - 7.3e-13 47.1 1.3 0.014 14.9 0.0 6.2 6 0 0 6 6 6 3 EF hand EF-hand_8 PF13833.6 OQS02289.1 - 5.3e-11 42.2 1.4 2.8e-05 23.8 0.0 4.5 4 0 0 4 4 4 3 EF-hand domain pair Kinase-like PF14531.6 OQS02289.1 - 1.9e-10 40.5 0.0 0.0016 17.8 0.0 3.6 4 0 0 4 4 4 3 Kinase-like Pkinase_fungal PF17667.1 OQS02289.1 - 7.2e-08 31.6 3.5 0.0002 20.3 0.0 2.6 3 0 0 3 3 3 2 Fungal protein kinase Kdo PF06293.14 OQS02289.1 - 8.6e-08 31.8 6.6 0.0023 17.3 0.3 3.3 3 0 0 3 3 3 3 Lipopolysaccharide kinase (Kdo/WaaP) family EF-hand_9 PF14658.6 OQS02289.1 - 0.00019 21.7 0.6 1.4 9.3 0.0 4.4 4 0 0 4 4 4 1 EF-hand domain EF-hand_5 PF13202.6 OQS02289.1 - 0.00023 20.5 0.3 2.4 7.8 0.0 4.8 4 0 0 4 4 4 1 EF hand Pox_ser-thr_kin PF05445.11 OQS02289.1 - 0.012 14.6 0.2 0.11 11.4 0.0 2.2 2 0 0 2 2 2 0 Poxvirus serine/threonine protein kinase Haspin_kinase PF12330.8 OQS02289.1 - 0.024 13.6 1.8 0.031 13.2 0.2 1.9 2 0 0 2 2 2 0 Haspin like kinase domain APH PF01636.23 OQS02289.1 - 0.027 14.4 3.7 4.1 7.3 0.3 3.7 3 1 0 3 3 3 0 Phosphotransferase enzyme family SPARC_Ca_bdg PF10591.9 OQS02289.1 - 1 9.7 8.9 2.1 8.7 0.2 4.0 5 0 0 5 5 5 0 Secreted protein acidic and rich in cysteine Ca binding region LicD PF04991.13 OQS02290.1 - 0.04 14.1 0.5 0.067 13.3 0.5 1.3 1 0 0 1 1 1 0 LicD family mRNA_cap_C PF03919.15 OQS02291.1 - 0.59 10.8 3.4 3.1 8.5 3.4 2.2 1 1 0 1 1 1 0 mRNA capping enzyme, C-terminal domain V_ATPase_I PF01496.19 OQS02292.1 - 1.5e-113 380.4 0.0 1.7e-113 380.3 0.0 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family ADIP PF11559.8 OQS02292.1 - 0.041 14.0 2.7 0.065 13.3 0.3 2.1 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding DUF3632 PF12311.8 OQS02292.1 - 0.065 13.7 0.7 10 6.5 0.0 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF3632) LRR_6 PF13516.6 OQS02293.1 - 2.3e-10 39.6 8.1 0.00053 19.8 0.1 4.7 5 0 0 5 5 5 3 Leucine Rich repeat PH PF00169.29 OQS02294.1 - 7e-12 45.8 0.0 2.1e-11 44.3 0.0 1.8 2 0 0 2 2 2 1 PH domain PH_11 PF15413.6 OQS02294.1 - 4.4e-05 23.9 0.1 0.0001 22.6 0.1 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain RA PF00788.23 OQS02294.1 - 0.0001 22.9 0.0 0.00025 21.6 0.0 1.7 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain RGS PF00615.19 OQS02294.1 - 0.00013 22.2 0.0 0.00056 20.2 0.0 2.1 1 1 0 1 1 1 1 Regulator of G protein signaling domain PLN_propep PF16485.5 OQS02294.1 - 0.077 12.7 0.1 5.6 6.8 0.0 2.5 2 0 0 2 2 2 0 Protealysin propeptide PH_8 PF15409.6 OQS02294.1 - 0.11 12.8 0.1 0.75 10.1 0.0 2.3 2 0 0 2 2 2 0 Pleckstrin homology domain DUF4464 PF14713.6 OQS02295.1 - 1.4e-68 230.8 0.1 1.6e-68 230.6 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4464) TBCC PF07986.12 OQS02296.1 - 1.6e-42 144.0 1.3 2.7e-42 143.3 1.3 1.4 1 0 0 1 1 1 1 Tubulin binding cofactor C Clathrin_lg_ch PF01086.17 OQS02296.1 - 1.3e-15 58.1 4.4 2.4e-15 57.3 4.4 1.4 1 0 0 1 1 1 1 Clathrin light chain CAP_C PF08603.11 OQS02296.1 - 1.4 8.6 5.4 1.9 8.1 1.2 2.2 1 1 1 2 2 2 0 Adenylate cyclase associated (CAP) C terminal BBP1_N PF15271.6 OQS02296.1 - 2.4 8.9 5.6 1.5 9.6 1.9 2.3 1 1 1 2 2 2 0 Spindle pole body component BBP1, Mps2-binding protein HNH_repeat PF18780.1 OQS02296.1 - 8.5 6.3 9.2 0.97 9.3 2.3 2.3 2 0 0 2 2 2 0 Homing endonuclease repeat DUF4291 PF14124.6 OQS02297.1 - 1.3e-52 178.3 0.3 1.9e-52 177.7 0.3 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4291) Thg1 PF04446.12 OQS02297.1 - 4.5e-51 172.1 0.2 8.6e-51 171.2 0.2 1.5 1 0 0 1 1 1 1 tRNAHis guanylyltransferase Thg1C PF14413.6 OQS02297.1 - 3.3e-38 130.6 1.0 6.4e-38 129.7 1.0 1.4 1 0 0 1 1 1 1 Thg1 C terminal domain Pkinase PF00069.25 OQS02299.1 - 6.3e-45 153.6 0.0 9.5e-45 153.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQS02299.1 - 6.3e-43 146.9 0.0 1e-42 146.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OQS02299.1 - 0.0019 17.1 0.0 0.0028 16.5 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase LRR_4 PF12799.7 OQS02299.1 - 0.01 16.2 2.7 0.01 16.2 2.7 3.2 2 1 2 4 4 4 0 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 OQS02299.1 - 3.3 7.6 6.5 2.2 8.1 1.3 2.6 2 1 1 3 3 3 0 Leucine rich repeat Pkinase_Tyr PF07714.17 OQS02301.1 - 7.4e-38 130.3 0.0 1.4e-37 129.4 0.0 1.4 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.25 OQS02301.1 - 3.1e-37 128.4 0.0 2e-36 125.7 0.0 1.9 2 0 0 2 2 2 1 Protein kinase domain HHH_3 PF12836.7 OQS02302.1 - 0.0021 18.3 0.0 0.0029 17.8 0.0 1.2 1 0 0 1 1 1 1 Helix-hairpin-helix motif FYVE PF01363.21 OQS02303.1 - 3.3e-08 33.5 7.0 3.3e-08 33.5 7.0 2.1 2 0 0 2 2 2 1 FYVE zinc finger FYVE_2 PF02318.16 OQS02303.1 - 0.00031 20.9 9.3 0.00063 19.9 6.5 2.3 2 0 0 2 2 2 1 FYVE-type zinc finger DZR PF12773.7 OQS02303.1 - 1.9 8.6 10.4 29 4.8 9.8 2.7 1 1 1 2 2 2 0 Double zinc ribbon MFS_2 PF13347.6 OQS02304.1 - 0.037 12.6 3.8 0.085 11.4 3.7 1.5 1 1 0 1 1 1 0 MFS/sugar transport protein DUF1340 PF07067.11 OQS02304.1 - 0.041 13.3 0.0 0.063 12.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1340) Pox_A14 PF05767.12 OQS02304.1 - 0.083 13.1 2.0 0.084 13.0 0.5 1.7 1 1 0 1 1 1 0 Poxvirus virion envelope protein A14 DUF2976 PF11190.8 OQS02304.1 - 0.11 12.3 4.6 2.6 7.9 0.2 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF2976) AMP-binding PF00501.28 OQS02305.1 - 6.4e-86 288.6 0.0 7.9e-86 288.3 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme Cas_Cas2CT1978 PF09707.10 OQS02305.1 - 0.01 15.9 0.0 0.035 14.2 0.0 1.9 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Cas2CT1978) Aminotran_1_2 PF00155.21 OQS02306.1 - 5.5e-53 180.4 0.0 6.4e-53 180.2 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 OQS02306.1 - 0.00036 19.2 0.0 0.00064 18.4 0.0 1.4 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme HNOBA PF07701.14 OQS02306.1 - 0.0079 15.7 0.0 1.5 8.2 0.0 2.4 2 0 0 2 2 2 2 Heme NO binding associated START PF01852.19 OQS02307.1 - 1.6e-19 70.2 0.0 4.8e-13 49.0 0.0 2.3 2 0 0 2 2 2 2 START domain PH PF00169.29 OQS02307.1 - 9.7e-10 38.9 0.8 3.4e-09 37.2 0.3 2.1 2 0 0 2 2 2 1 PH domain PH_11 PF15413.6 OQS02307.1 - 6.7e-06 26.5 0.4 3.2e-05 24.3 0.4 2.1 1 1 0 1 1 1 1 Pleckstrin homology domain 2-oxoacid_dh PF00198.23 OQS02307.1 - 2.9e-05 23.6 0.4 0.89 8.9 0.0 3.3 3 1 0 3 3 3 2 2-oxoacid dehydrogenases acyltransferase (catalytic domain) SMC_N PF02463.19 OQS02309.1 - 1.1e-27 96.9 14.1 4.4e-27 95.0 14.1 2.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 OQS02309.1 - 8.8e-21 75.3 0.3 8.8e-21 75.3 0.3 5.4 2 2 3 5 5 3 1 AAA domain AAA_15 PF13175.6 OQS02309.1 - 5.1e-11 42.9 4.3 5.1e-11 42.9 4.3 4.1 2 2 1 3 3 2 1 AAA ATPase domain AAA_21 PF13304.6 OQS02309.1 - 1.4e-05 25.0 2.7 0.0014 18.5 0.1 3.0 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 OQS02309.1 - 0.00012 21.7 0.0 0.00027 20.6 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain Spc7 PF08317.11 OQS02309.1 - 0.00058 18.8 28.0 0.00058 18.8 28.0 4.9 2 2 3 5 5 5 3 Spc7 kinetochore protein Tropomyosin_1 PF12718.7 OQS02309.1 - 0.0021 18.2 14.7 0.0021 18.2 14.7 5.6 2 2 3 5 5 3 1 Tropomyosin like CEP63 PF17045.5 OQS02309.1 - 0.0024 17.8 10.7 0.0024 17.8 10.7 4.7 3 2 2 5 5 4 1 Centrosomal protein of 63 kDa SbcCD_C PF13558.6 OQS02309.1 - 0.015 15.6 0.0 0.074 13.3 0.0 2.3 2 0 0 2 2 1 0 Putative exonuclease SbcCD, C subunit AAA_16 PF13191.6 OQS02309.1 - 0.38 11.1 0.0 0.38 11.1 0.0 4.1 3 2 0 3 3 1 0 AAA ATPase domain Baculo_PEP_C PF04513.12 OQS02309.1 - 7.5 6.6 39.0 0.091 12.8 1.5 5.8 3 2 3 7 7 7 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF3584 PF12128.8 OQS02309.1 - 9.7 3.6 86.5 0.0034 15.0 13.0 3.3 2 1 0 2 2 2 0 Protein of unknown function (DUF3584) DUF1664 PF07889.12 OQS02311.1 - 0.65 10.0 21.1 3.4 7.7 3.9 4.0 3 1 1 4 4 4 0 Protein of unknown function (DUF1664) ATG16 PF08614.11 OQS02311.1 - 1.7 8.8 45.7 0.11 12.7 10.1 3.9 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) TSC22 PF01166.18 OQS02311.1 - 4.7 7.6 20.3 0.18 12.1 0.4 4.9 5 1 1 6 6 6 0 TSC-22/dip/bun family HALZ PF02183.18 OQS02311.1 - 7.7 6.8 24.9 2.6 8.3 1.2 5.4 5 1 0 5 5 5 0 Homeobox associated leucine zipper TIP41 PF04176.13 OQS02312.1 - 8.6e-08 31.9 0.3 1.1e-06 28.3 0.3 2.0 1 1 0 1 1 1 1 TIP41-like family DAGAT PF03982.13 OQS02313.1 - 3.6e-41 141.0 0.1 4.4e-41 140.7 0.1 1.1 1 0 0 1 1 1 1 Diacylglycerol acyltransferase DAGAT PF03982.13 OQS02314.1 - 7.1e-39 133.5 0.4 8.9e-39 133.2 0.4 1.2 1 0 0 1 1 1 1 Diacylglycerol acyltransferase GRDP-like PF07173.12 OQS02315.1 - 1.7e-17 64.4 0.5 5.7e-17 62.7 0.1 2.1 2 0 0 2 2 2 1 Glycine-rich domain-containing protein-like PH PF00169.29 OQS02315.1 - 0.00055 20.4 0.4 0.0014 19.1 0.1 1.8 2 0 0 2 2 2 1 PH domain PhyH PF05721.13 OQS02316.1 - 4.7e-10 40.1 0.0 8e-10 39.3 0.0 1.4 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Trypsin_2 PF13365.6 OQS02317.1 - 4.7e-27 95.7 0.1 5.4e-12 46.8 0.0 2.8 3 0 0 3 3 3 2 Trypsin-like peptidase domain PAN_4 PF14295.6 OQS02317.1 - 6.5e-07 29.2 4.6 2.1e-06 27.5 4.6 2.0 1 0 0 1 1 1 1 PAN domain PAN_1 PF00024.26 OQS02317.1 - 0.00015 21.6 0.4 0.00015 21.6 0.4 2.2 2 0 0 2 2 2 1 PAN domain PAN_2 PF08276.11 OQS02317.1 - 0.12 12.5 3.9 0.41 10.8 3.9 1.9 1 0 0 1 1 1 0 PAN-like domain CobT PF06213.12 OQS02317.1 - 0.82 9.0 8.6 1.8 7.9 8.6 1.5 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Ndc1_Nup PF09531.10 OQS02317.1 - 5.8 5.5 6.5 11 4.6 6.5 1.4 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF244 PF03112.14 OQS02318.1 - 0.14 12.0 7.9 0.54 10.1 0.4 2.6 1 1 0 2 2 2 0 Uncharacterized protein family (ORF7) DUF FliD_N PF02465.18 OQS02318.1 - 1.9 9.3 10.2 2.1e+02 2.7 10.2 3.3 1 1 0 1 1 1 0 Flagellar hook-associated protein 2 N-terminus TFIIIC_delta PF12657.7 OQS02319.1 - 4.1e-07 30.1 0.4 1.4e-06 28.3 0.0 2.1 2 0 0 2 2 2 1 Transcription factor IIIC subunit delta N-term zf-TFIIIC PF12660.7 OQS02319.1 - 0.00012 22.0 2.1 0.00036 20.5 2.1 1.8 1 0 0 1 1 1 1 Putative zinc-finger of transcription factor IIIC complex ANAPC4_WD40 PF12894.7 OQS02319.1 - 0.023 15.0 0.7 14 6.0 0.0 3.8 2 1 1 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain AAA_18 PF13238.6 OQS02320.1 - 1.4e-08 35.3 0.0 3.3e-08 34.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 OQS02320.1 - 0.00042 20.5 0.0 0.00073 19.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 OQS02320.1 - 0.00044 19.6 0.0 0.00088 18.6 0.0 1.6 1 0 0 1 1 1 1 Zeta toxin NACHT PF05729.12 OQS02320.1 - 0.0083 16.1 0.0 0.014 15.3 0.0 1.4 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 OQS02320.1 - 0.01 16.2 0.0 0.019 15.3 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain AAA_28 PF13521.6 OQS02320.1 - 0.011 16.0 0.0 0.019 15.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 OQS02320.1 - 0.022 14.7 0.0 0.049 13.5 0.0 1.6 1 0 0 1 1 1 0 RsgA GTPase DnaB_C PF03796.15 OQS02320.1 - 0.035 13.4 0.0 0.056 12.8 0.0 1.3 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain CPT PF07931.12 OQS02320.1 - 0.048 13.5 0.0 0.085 12.7 0.0 1.3 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein KTI12 PF08433.10 OQS02320.1 - 0.055 12.9 0.0 0.097 12.1 0.0 1.4 1 0 0 1 1 1 0 Chromatin associated protein KTI12 APS_kinase PF01583.20 OQS02320.1 - 0.16 11.8 0.2 0.7 9.8 0.0 2.1 2 0 0 2 2 2 0 Adenylylsulphate kinase ATP_bind_1 PF03029.17 OQS02321.1 - 6.9e-87 291.2 0.0 9.2e-87 290.8 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein SAE2 PF08573.10 OQS02321.1 - 5.2e-07 30.8 16.3 0.00051 21.1 1.3 3.4 2 2 1 3 3 3 2 DNA repair protein endonuclease SAE2/CtIP C-terminus CLP1_P PF16575.5 OQS02321.1 - 0.00062 19.6 0.0 0.0015 18.4 0.0 1.6 1 0 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_24 PF13479.6 OQS02321.1 - 0.0038 17.0 0.0 0.0078 15.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 OQS02321.1 - 0.0039 17.5 0.2 0.075 13.3 0.0 2.6 3 0 0 3 3 2 1 AAA domain AAA_18 PF13238.6 OQS02321.1 - 0.0041 17.6 0.0 0.016 15.8 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 OQS02321.1 - 0.0064 16.2 1.0 0.014 15.1 0.0 2.1 3 0 0 3 3 3 1 AAA domain DUF4482 PF14818.6 OQS02321.1 - 0.01 16.7 1.8 0.018 15.9 1.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4482) AAA_7 PF12775.7 OQS02321.1 - 0.011 15.2 0.1 0.18 11.3 0.0 2.2 2 0 0 2 2 2 0 P-loop containing dynein motor region EcsC PF12787.7 OQS02321.1 - 0.022 14.5 0.5 0.041 13.5 0.5 1.4 1 0 0 1 1 1 0 EcsC protein family AAA_33 PF13671.6 OQS02321.1 - 0.03 14.5 0.1 0.16 12.1 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 OQS02321.1 - 0.039 14.3 0.0 0.38 11.1 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain AAA_31 PF13614.6 OQS02321.1 - 0.1 12.5 0.1 6.8 6.6 0.0 2.5 2 0 0 2 2 2 0 AAA domain Fer4_NifH PF00142.18 OQS02321.1 - 0.12 11.9 0.3 0.45 9.9 0.0 2.0 1 1 1 2 2 2 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family RNA_helicase PF00910.22 OQS02321.1 - 0.13 12.7 0.0 0.35 11.3 0.0 1.8 2 0 0 2 2 1 0 RNA helicase RsgA_GTPase PF03193.16 OQS02321.1 - 0.16 11.9 0.0 16 5.4 0.0 2.5 2 0 0 2 2 2 0 RsgA GTPase ArfGap PF01412.18 OQS02322.1 - 1.3e-25 89.7 1.2 1.3e-25 89.7 1.2 1.5 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf zf-B_box PF00643.24 OQS02322.1 - 0.00015 21.8 1.5 0.00022 21.3 1.5 1.2 1 0 0 1 1 1 1 B-box zinc finger Ank_2 PF12796.7 OQS02326.1 - 4.5e-108 354.0 33.0 3.3e-20 72.5 1.4 7.1 1 1 7 8 8 8 8 Ankyrin repeats (3 copies) Ank PF00023.30 OQS02326.1 - 3.2e-89 289.8 46.5 4.9e-08 33.1 0.1 13.1 12 1 1 13 13 13 13 Ankyrin repeat Ank_4 PF13637.6 OQS02326.1 - 1.5e-78 258.2 30.4 5.3e-11 42.8 0.1 10.5 2 2 9 11 11 11 11 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQS02326.1 - 8.3e-78 247.0 11.0 1.2e-05 25.3 0.0 13.1 13 0 0 13 13 13 13 Ankyrin repeat Ank_5 PF13857.6 OQS02326.1 - 1.6e-42 143.0 20.6 7.1e-08 32.6 0.0 9.4 2 2 10 12 12 12 12 Ankyrin repeats (many copies) Imm_superinfect PF14373.6 OQS02326.1 - 1.4e-06 28.1 0.2 3.4 7.7 0.0 6.5 8 0 0 8 8 8 2 Superinfection immunity protein Arg_repressor PF01316.21 OQS02326.1 - 2.6e-06 27.1 9.1 4 7.3 0.0 9.7 11 0 0 11 11 11 1 Arginine repressor, DNA binding domain CUE PF02845.16 OQS02326.1 - 0.00027 20.6 9.3 0.83 9.4 0.0 6.8 7 0 0 7 7 7 1 CUE domain VWA_3_C PF18571.1 OQS02326.1 - 0.018 14.9 2.6 26 4.8 0.0 5.4 7 0 0 7 7 7 0 von Willebrand factor type A C-terminal domain Arrestin_N PF00339.29 OQS02327.1 - 8.9e-14 51.8 0.1 6.2e-12 45.8 0.0 2.7 3 0 0 3 3 3 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 OQS02327.1 - 1.1e-12 48.5 1.3 8.1e-11 42.5 0.2 2.4 2 1 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain LDB19 PF13002.7 OQS02327.1 - 0.011 15.5 0.0 0.025 14.3 0.0 1.5 1 0 0 1 1 1 0 Arrestin_N terminal like PQ-loop PF04193.14 OQS02330.1 - 1.5e-27 95.1 17.5 5.6e-15 54.9 0.5 2.9 3 0 0 3 3 3 2 PQ loop repeat PPP4R2 PF09184.11 OQS02330.1 - 1.2e-13 51.4 0.9 1.2e-13 51.4 0.9 2.2 2 1 0 2 2 2 1 PPP4R2 DUF5090 PF17009.5 OQS02330.1 - 0.42 10.5 5.0 1.3 8.9 5.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF5090) DUF2304 PF10066.9 OQS02330.1 - 2.7 8.2 7.7 13 6.1 7.7 2.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2304) ANAPC4_WD40 PF12894.7 OQS02331.1 - 2.3e-20 72.7 1.2 0.0042 17.4 0.0 8.2 1 1 6 8 8 8 6 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 OQS02331.1 - 3.8e-12 46.5 23.6 0.27 12.2 0.0 10.2 9 1 1 10 10 10 5 WD domain, G-beta repeat PQQ_2 PF13360.6 OQS02331.1 - 0.00015 21.4 1.8 1.4 8.5 0.0 3.8 2 2 2 4 4 4 2 PQQ-like domain ELYS-bb PF16687.5 OQS02331.1 - 0.0011 17.6 0.0 4.8 5.7 0.0 3.1 2 1 1 3 3 3 3 beta-propeller of ELYS nucleoporin WD40_like PF17005.5 OQS02331.1 - 0.0047 16.3 0.0 0.013 14.9 0.0 1.8 2 0 0 2 2 2 1 WD40-like domain HPS3_N PF14761.6 OQS02331.1 - 0.0082 15.7 0.0 3.5 7.1 0.0 3.5 2 1 0 3 3 3 1 Hermansky-Pudlak syndrome 3 Ge1_WD40 PF16529.5 OQS02331.1 - 0.044 12.7 0.1 15 4.4 0.0 3.8 4 1 0 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein ABC_membrane PF00664.23 OQS02332.1 - 1.8e-32 113.1 11.6 2.4e-32 112.7 11.6 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 OQS02332.1 - 2.5e-15 57.2 0.1 5.2e-15 56.2 0.1 1.6 1 0 0 1 1 1 1 ABC transporter RsgA_GTPase PF03193.16 OQS02332.1 - 0.0058 16.5 0.0 0.015 15.2 0.0 1.6 1 0 0 1 1 1 1 RsgA GTPase DUF87 PF01935.17 OQS02332.1 - 0.006 16.7 0.3 0.019 15.1 0.3 1.8 2 0 0 2 2 2 1 Helicase HerA, central domain AAA_22 PF13401.6 OQS02332.1 - 0.011 16.1 0.0 0.03 14.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 OQS02332.1 - 0.029 14.1 0.2 0.12 12.1 0.2 1.9 2 0 0 2 2 2 0 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 OQS02332.1 - 0.058 13.5 0.0 0.14 12.3 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_24 PF13479.6 OQS02332.1 - 0.069 12.9 0.0 0.15 11.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain ATP-synt_ab PF00006.25 OQS02332.1 - 0.1 12.2 0.1 0.34 10.5 0.0 1.8 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain SBBP PF06739.11 OQS02333.1 - 0.002 18.1 5.9 0.058 13.4 0.3 4.3 3 0 0 3 3 3 2 Beta-propeller repeat Calycin_like PF13944.6 OQS02333.1 - 3.4 8.0 10.5 0.1 12.9 0.3 3.8 4 0 0 4 4 4 0 Calycin-like beta-barrel domain zf-MYND PF01753.18 OQS02334.1 - 9.1e-09 35.3 14.6 9.1e-09 35.3 14.6 2.5 2 1 0 2 2 2 1 MYND finger zf-C6H2 PF15801.5 OQS02334.1 - 0.00049 20.4 9.4 0.00049 20.4 9.4 2.6 2 0 0 2 2 2 1 zf-MYND-like zinc finger, mRNA-binding Drf_GBD PF06371.13 OQS02334.1 - 0.0012 18.5 0.3 0.0036 16.9 0.3 1.9 1 0 0 1 1 1 1 Diaphanous GTPase-binding Domain Arm PF00514.23 OQS02334.1 - 0.016 15.3 0.3 1.3 9.2 0.1 3.2 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 OQS02334.1 - 0.063 13.7 0.2 0.5 10.8 0.0 2.5 2 0 0 2 2 2 0 HEAT repeats DUF1180 PF06679.12 OQS02335.1 - 0.38 11.1 2.3 0.51 10.7 0.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1180) Nup214_FG PF18617.1 OQS02335.1 - 1 9.9 3.9 7.5 7.2 0.1 2.7 2 1 0 2 2 2 0 Nucleoporin Nup214 phenylalanine-glycine (FG) domain Ank_2 PF12796.7 OQS02336.1 - 2e-21 76.3 9.5 3.4e-05 24.3 0.2 5.9 3 2 3 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQS02336.1 - 6.4e-21 74.4 8.4 0.00059 20.3 0.1 8.3 6 2 2 8 8 8 7 Ankyrin repeats (many copies) Ank_5 PF13857.6 OQS02336.1 - 1.1e-13 51.1 9.4 0.16 12.3 0.0 9.6 4 4 6 10 10 10 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQS02336.1 - 1.3e-13 49.8 3.2 5.1 8.0 0.0 10.7 9 2 2 11 11 11 2 Ankyrin repeat Ank PF00023.30 OQS02336.1 - 6.4e-05 23.2 3.1 12 6.5 0.0 7.5 6 3 2 8 8 8 1 Ankyrin repeat DUF3447 PF11929.8 OQS02336.1 - 0.015 15.3 7.9 2 8.5 0.1 4.5 3 2 3 6 6 6 0 Domain of unknown function (DUF3447) zf-4CXXC_R1 PF10497.9 OQS02336.1 - 0.12 12.6 0.0 0.45 10.8 0.0 2.1 2 0 0 2 2 2 0 Zinc-finger domain of monoamine-oxidase A repressor R1 Tim17 PF02466.19 OQS02337.1 - 1.7e-09 38.0 8.9 8.8e-09 35.7 9.0 1.8 1 1 1 2 2 2 2 Tim17/Tim22/Tim23/Pmp24 family DUF3918 PF13056.6 OQS02337.1 - 1.6 8.4 4.3 1.8 8.3 0.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3918) Acetyltransf_1 PF00583.25 OQS02338.1 - 7.4e-11 42.3 0.0 1.1e-10 41.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 OQS02338.1 - 1.3e-07 31.6 0.1 2.5e-07 30.7 0.1 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 OQS02338.1 - 3.8e-07 30.4 0.4 7.2e-07 29.5 0.1 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 OQS02338.1 - 8.6e-05 22.4 0.0 0.00018 21.4 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_4 PF13420.7 OQS02338.1 - 0.00093 19.4 0.1 0.013 15.6 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Lipase_GDSL_3 PF14606.6 OQS02338.1 - 0.018 15.2 0.0 0.038 14.1 0.0 1.6 1 1 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family RNA_pol_Rpb4 PF03874.16 OQS02338.1 - 0.03 14.6 0.7 0.11 12.8 0.1 2.0 2 0 0 2 2 2 0 RNA polymerase Rpb4 Acetyltransf_9 PF13527.7 OQS02338.1 - 0.063 13.4 0.1 0.13 12.4 0.1 1.5 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 OQS02338.1 - 0.073 13.2 0.0 0.14 12.3 0.0 1.5 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Ank_2 PF12796.7 OQS02339.1 - 6.2e-05 23.5 0.0 8.6e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OQS02339.1 - 0.0016 18.7 0.0 0.086 13.2 0.0 2.2 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 OQS02339.1 - 0.007 16.9 0.0 0.27 11.9 0.0 2.1 1 1 1 2 2 2 2 Ankyrin repeats (many copies) DUF5049 PF16468.5 OQS02339.1 - 0.02 14.8 0.7 4.8 7.2 0.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF5049) EGF_2 PF07974.13 OQS02340.1 - 2.3e-14 53.4 58.6 8.8e-06 26.0 4.9 6.9 7 1 0 7 7 7 4 EGF-like domain Laminin_EGF PF00053.24 OQS02340.1 - 0.00055 20.0 37.3 0.039 14.1 9.3 4.3 3 2 0 3 3 3 3 Laminin EGF domain EGF PF00008.27 OQS02340.1 - 0.18 12.1 51.7 0.68 10.3 8.6 5.4 6 0 0 6 6 6 0 EGF-like domain Ank_2 PF12796.7 OQS02341.1 - 2.6e-49 165.7 40.4 1.4e-07 32.0 0.0 12.6 6 3 8 15 15 15 13 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQS02341.1 - 3.2e-39 132.8 32.8 0.00011 22.6 0.1 16.3 11 2 6 17 17 17 14 Ankyrin repeats (many copies) Ank_5 PF13857.6 OQS02341.1 - 2.2e-31 107.5 47.1 0.043 14.1 0.1 21.4 11 7 14 25 25 25 9 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQS02341.1 - 6.3e-18 63.0 35.3 2.5 8.9 0.1 22.8 25 1 1 26 26 26 1 Ankyrin repeat DUF5049 PF16468.5 OQS02341.1 - 4.1e-06 26.6 7.2 28 4.7 0.1 8.5 7 2 2 9 9 9 0 Domain of unknown function (DUF5049) DUF3447 PF11929.8 OQS02341.1 - 2.9e-05 23.9 27.4 7.7 6.6 0.2 10.0 8 2 1 10 10 10 2 Domain of unknown function (DUF3447) Ank PF00023.30 OQS02341.1 - 0.00064 20.1 25.1 8.8 7.0 0.1 13.1 10 4 3 13 13 13 1 Ankyrin repeat zf-4CXXC_R1 PF10497.9 OQS02341.1 - 0.19 12.0 4.4 11 6.3 0.1 4.7 4 1 0 4 4 4 0 Zinc-finger domain of monoamine-oxidase A repressor R1 Antimicrobial13 PF08108.11 OQS02341.1 - 1.5 9.0 6.7 3.2 8.0 1.7 2.8 2 0 0 2 2 2 0 Halocidin family FA_desaturase PF00487.24 OQS02342.1 - 8.8e-29 101.1 17.9 1.4e-28 100.5 17.9 1.3 1 0 0 1 1 1 1 Fatty acid desaturase DUF3474 PF11960.8 OQS02342.1 - 2.2e-06 27.9 0.0 4.6e-06 26.9 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3474) Tenui_PVC2 PF06656.11 OQS02342.1 - 0.018 13.0 0.1 0.026 12.4 0.1 1.1 1 0 0 1 1 1 0 Tenuivirus PVC2 protein VIT1 PF01988.19 OQS02342.1 - 0.14 12.0 0.2 0.23 11.3 0.2 1.3 1 0 0 1 1 1 0 VIT family Ion_trans PF00520.31 OQS02343.1 - 5.2e-159 526.9 67.1 3e-44 151.1 8.7 4.2 4 0 0 4 4 4 4 Ion transport protein GPHH PF16905.5 OQS02343.1 - 3.8e-10 39.4 0.0 1.1e-09 37.9 0.0 1.8 1 0 0 1 1 1 1 Voltage-dependent L-type calcium channel, IQ-associated STI1 PF17830.1 OQS02343.1 - 3.5e-08 33.3 1.2 7.4e-08 32.2 0.0 2.2 2 0 0 2 2 2 1 STI1 domain PKD_channel PF08016.12 OQS02343.1 - 0.027 13.1 65.4 0.021 13.5 0.8 9.7 8 2 1 9 9 9 0 Polycystin cation channel EF-hand_1 PF00036.32 OQS02343.1 - 0.13 11.9 0.0 0.4 10.3 0.0 1.9 1 0 0 1 1 1 0 EF hand DUF5598 PF18127.1 OQS02343.1 - 0.15 12.5 0.2 0.87 10.1 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF5598) HMG-CoA_red PF00368.18 OQS02345.1 - 6.9e-121 403.7 3.8 9.9e-121 403.2 3.8 1.2 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A reductase F5_F8_type_C PF00754.25 OQS02345.1 - 0.00079 19.5 0.0 0.0052 16.9 0.0 2.2 2 1 0 2 2 2 1 F5/8 type C domain tRNA_bind PF01588.20 OQS02346.1 - 7.1e-24 83.7 0.0 1e-23 83.3 0.0 1.2 1 0 0 1 1 1 1 Putative tRNA binding domain ARL2_Bind_BART PF11527.8 OQS02347.1 - 2e-32 111.7 1.0 2e-32 111.7 1.0 2.8 2 1 0 3 3 3 1 The ARF-like 2 binding protein BART Ribosomal_L16 PF00252.18 OQS02347.1 - 3.7e-12 46.4 0.0 3.7e-12 46.4 0.0 2.7 4 0 0 4 4 4 1 Ribosomal protein L16p/L10e ECH_1 PF00378.20 OQS02348.1 - 1.2e-33 116.5 0.0 1.4e-33 116.3 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 OQS02348.1 - 2.2e-28 99.7 0.0 2.5e-28 99.5 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase HECT PF00632.25 OQS02349.1 - 1e-55 189.4 0.0 1.1e-55 189.3 0.0 1.0 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) adh_short_C2 PF13561.6 OQS02350.1 - 5.2e-68 229.1 0.1 6e-68 228.9 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OQS02350.1 - 9.6e-18 64.3 0.1 1.2e-17 64.0 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase Enoyl_reductase PF12241.8 OQS02350.1 - 0.00038 19.9 0.1 0.0095 15.3 0.0 2.1 1 1 1 2 2 2 1 Trans-2-enoyl-CoA reductase catalytic region Polysacc_synt_2 PF02719.15 OQS02350.1 - 0.035 13.2 0.0 0.044 12.9 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein KR PF08659.10 OQS02350.1 - 0.04 13.8 0.1 0.31 10.9 0.0 2.0 1 1 1 2 2 2 0 KR domain Leptin PF02024.15 OQS02350.1 - 0.058 13.2 0.0 0.093 12.5 0.0 1.3 1 0 0 1 1 1 0 Leptin DUF1115 PF06544.12 OQS02351.1 - 1.2e-09 38.5 0.0 1.4e-09 38.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1115) PALP PF00291.25 OQS02352.1 - 6e-30 104.7 0.0 7.1e-30 104.4 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme zf-C3HC4_2 PF13923.6 OQS02353.1 - 2.3e-09 36.9 10.1 6.3e-09 35.5 10.1 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 OQS02353.1 - 4.2e-09 36.1 10.0 4.2e-09 36.1 10.0 1.7 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) LRR_9 PF14580.6 OQS02353.1 - 1.6e-08 34.2 1.5 3.6e-08 33.1 0.3 2.2 2 0 0 2 2 2 1 Leucine-rich repeat Prok-RING_4 PF14447.6 OQS02353.1 - 1.5e-07 31.1 7.7 3.5e-07 30.0 7.7 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 OQS02353.1 - 3.9e-07 30.3 9.1 1.1e-06 28.8 9.1 1.9 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 OQS02353.1 - 4.1e-07 29.8 11.5 1.1e-06 28.4 11.5 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OQS02353.1 - 4.1e-06 26.7 10.7 4.1e-06 26.7 10.7 1.9 2 0 0 2 2 1 1 zinc-RING finger domain zf-RING_6 PF14835.6 OQS02353.1 - 6.5e-05 22.7 2.4 0.00014 21.7 2.4 1.5 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-RING_UBOX PF13445.6 OQS02353.1 - 0.00019 21.4 7.5 0.00046 20.1 7.5 1.7 1 0 0 1 1 1 1 RING-type zinc-finger LRR_4 PF12799.7 OQS02353.1 - 0.0002 21.7 6.1 0.0019 18.6 0.8 3.6 2 1 1 3 3 3 1 Leucine Rich repeats (2 copies) zf-rbx1 PF12678.7 OQS02353.1 - 0.00027 21.2 5.9 0.00086 19.5 5.9 1.9 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-UDP PF14569.6 OQS02353.1 - 0.0025 17.9 4.9 0.0074 16.4 4.9 1.8 1 0 0 1 1 1 1 Zinc-binding RING-finger DHR10 PF18595.1 OQS02353.1 - 0.0072 16.4 2.7 0.0072 16.4 2.7 6.9 3 1 3 6 6 5 1 Designed helical repeat protein 10 domain zf-RING_4 PF14570.6 OQS02353.1 - 0.014 15.2 7.2 0.041 13.7 7.2 1.8 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain LRR_8 PF13855.6 OQS02353.1 - 0.017 14.9 7.0 1.4 8.7 5.2 3.1 2 1 1 3 3 3 0 Leucine rich repeat DUF3251 PF11622.8 OQS02353.1 - 0.043 13.5 1.1 0.15 11.7 1.1 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3251) zf-ANAPC11 PF12861.7 OQS02353.1 - 0.21 11.6 3.6 0.45 10.6 3.6 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.6 OQS02353.1 - 0.29 11.3 8.0 0.73 10.1 8.0 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_10 PF16685.5 OQS02353.1 - 0.77 9.9 11.4 0.27 11.4 7.6 2.3 2 0 0 2 2 1 0 zinc RING finger of MSL2 PepSY_TM_like_2 PF16357.5 OQS02353.1 - 1.1 9.2 0.0 1.1 9.2 0.0 3.0 3 1 0 3 3 1 0 Putative PepSY_TM-like zf-RING_11 PF17123.5 OQS02353.1 - 1.9 8.3 6.4 4.6 7.1 6.4 1.7 1 0 0 1 1 1 0 RING-like zinc finger LRR_1 PF00560.33 OQS02353.1 - 5.5 8.0 7.0 80 4.4 0.1 4.2 3 1 0 3 3 3 0 Leucine Rich Repeat SLC35F PF06027.12 OQS02354.1 - 1.4e-45 156.1 23.7 1.7e-45 155.8 23.7 1.0 1 0 0 1 1 1 1 Solute carrier family 35 CRT-like PF08627.10 OQS02354.1 - 3.9e-09 35.9 3.3 3.9e-09 35.9 3.3 2.0 1 1 0 2 2 2 1 CRT-like, chloroquine-resistance transporter-like EamA PF00892.20 OQS02354.1 - 1.7e-08 34.7 39.7 9.5e-05 22.6 16.6 2.1 2 0 0 2 2 2 2 EamA-like transporter family UAA PF08449.11 OQS02354.1 - 0.02 14.1 20.1 0.076 12.2 20.1 1.9 1 1 0 1 1 1 0 UAA transporter family HILPDA PF15220.6 OQS02354.1 - 1.4 9.1 4.2 3.6 7.8 4.2 1.7 1 0 0 1 1 1 0 Hypoxia-inducible lipid droplet-associated EmrE PF13536.6 OQS02354.1 - 1.6 8.2 18.5 0.0081 15.8 5.8 2.2 1 1 0 2 2 2 0 Putative multidrug resistance efflux transporter WD40 PF00400.32 OQS02355.1 - 6e-64 210.5 23.7 1.2e-08 35.5 0.2 11.6 11 0 0 11 11 11 10 WD domain, G-beta repeat Utp13 PF08625.11 OQS02355.1 - 5.5e-44 149.5 0.8 8.8e-44 148.8 0.3 1.7 2 0 0 2 2 2 1 Utp13 specific WD40 associated domain ANAPC4_WD40 PF12894.7 OQS02355.1 - 6.3e-21 74.5 4.8 0.004 17.4 0.0 7.7 3 2 4 7 7 7 6 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 OQS02355.1 - 1.1e-10 40.8 17.4 0.00052 18.8 0.1 6.9 4 3 2 6 6 6 3 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 OQS02355.1 - 1.7e-09 36.9 2.8 0.13 10.9 0.0 5.8 2 2 2 5 5 5 3 Nup133 N terminal like WD40_like PF17005.5 OQS02355.1 - 4e-07 29.7 0.5 0.03 13.6 0.0 4.0 2 1 1 3 3 3 2 WD40-like domain eIF2A PF08662.11 OQS02355.1 - 4.9e-07 29.8 2.2 0.16 11.9 0.0 3.8 2 1 1 3 3 3 3 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.16 OQS02355.1 - 1.7e-06 26.9 0.9 0.021 13.4 0.1 3.5 2 2 1 3 3 3 3 Cytochrome D1 heme domain Ge1_WD40 PF16529.5 OQS02355.1 - 2.3e-06 26.8 11.8 0.44 9.5 0.1 6.5 3 3 4 7 7 7 3 WD40 region of Ge1, enhancer of mRNA-decapping protein p450 PF00067.22 OQS02355.1 - 0.013 14.3 1.4 0.045 12.5 0.5 2.0 2 0 0 2 2 2 0 Cytochrome P450 UTP15_C PF09384.10 OQS02355.1 - 0.063 13.0 0.8 0.16 11.6 0.8 1.6 1 1 0 1 1 1 0 UTP15 C terminal nos_propeller PF18764.1 OQS02355.1 - 0.11 12.4 0.0 0.34 10.8 0.0 1.9 1 0 0 1 1 1 0 Nitrous oxide reductase propeller repeat Holin_BhlA PF10960.8 OQS02356.1 - 0.012 15.6 1.8 1.7 8.7 0.1 4.0 3 0 0 3 3 3 0 BhlA holin family Tricorn_C1 PF14684.6 OQS02356.1 - 0.028 14.5 0.2 2.2 8.4 0.0 3.6 3 0 0 3 3 3 0 Tricorn protease C1 domain DUF5457 PF17540.2 OQS02356.1 - 0.2 11.8 1.3 12 6.0 0.1 3.4 3 0 0 3 3 3 0 Family of unknown function (DUF5457) TFIID_NTD2 PF04494.15 OQS02356.1 - 0.39 11.0 5.1 0.59 10.4 0.4 3.6 2 0 0 2 2 2 0 WD40 associated region in TFIID subunit, NTD2 domain DUF3899 PF13038.6 OQS02356.1 - 1.7 9.2 17.7 17 6.0 0.2 6.5 5 1 0 5 5 5 0 Domain of unknown function (DUF3899) HrpB2 PF09487.10 OQS02356.1 - 1.8 9.0 4.5 29 5.1 0.4 2.5 2 0 0 2 2 2 0 Bacterial type III secretion protein (HrpB2) SP_C-Propep PF08999.10 OQS02356.1 - 2.4 8.0 4.4 37 4.2 0.1 3.8 3 0 0 3 3 3 0 Surfactant protein C, N terminal propeptide EAV_GS PF01309.18 OQS02356.1 - 5.3 6.6 6.5 4.3 6.9 0.2 2.9 3 0 0 3 3 3 0 Equine arteritis virus small envelope glycoprotein CAP PF00188.26 OQS02358.1 - 3.8e-34 118.2 18.3 5.4e-12 46.6 0.1 4.1 4 0 0 4 4 4 3 Cysteine-rich secretory protein family PT PF04886.12 OQS02358.1 - 2.6e-07 30.1 21.8 2.6e-07 30.1 21.8 4.7 4 1 0 4 4 3 1 PT repeat TMEM154 PF15102.6 OQS02358.1 - 4e-05 23.5 2.5 9.1e-05 22.4 1.2 2.3 1 1 0 1 1 1 1 TMEM154 protein family RIFIN PF02009.16 OQS02358.1 - 0.0045 16.9 0.0 0.0073 16.2 0.0 1.2 1 0 0 1 1 1 1 Rifin FG-GAP PF01839.23 OQS02358.1 - 0.0081 16.3 0.1 8.5 6.6 0.0 3.2 3 0 0 3 3 3 1 FG-GAP repeat Pkinase_Tyr PF07714.17 OQS02358.1 - 0.033 13.5 0.0 0.071 12.4 0.0 1.5 1 0 0 1 1 1 0 Protein tyrosine kinase DUF2145 PF09916.9 OQS02358.1 - 0.051 13.2 1.2 1.8 8.2 0.0 2.9 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2145) Stevor PF17410.2 OQS02358.1 - 0.055 13.0 0.0 0.086 12.4 0.0 1.3 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame CD34_antigen PF06365.12 OQS02358.1 - 0.085 12.4 0.1 0.25 10.9 0.0 1.9 2 0 0 2 2 2 0 CD34/Podocalyxin family EphA2_TM PF14575.6 OQS02358.1 - 0.087 13.7 0.1 0.21 12.5 0.1 1.7 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain WTF PF03303.13 OQS02358.1 - 0.18 11.5 0.5 0.31 10.7 0.5 1.2 1 0 0 1 1 1 0 WTF protein ECSCR PF15820.5 OQS02358.1 - 5.7 6.8 6.9 11 5.9 6.2 1.8 1 1 0 1 1 1 0 Endothelial cell-specific chemotaxis regulator DUF5484 PF17583.2 OQS02359.1 - 1.2 8.8 4.0 2.6 7.8 0.5 2.3 1 1 1 2 2 2 0 Family of unknown function (DUF5484) Peptidase_C1 PF00112.23 OQS02360.1 - 7.7e-60 202.7 14.8 1.1e-59 202.2 14.8 1.2 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.15 OQS02360.1 - 8.2e-05 21.6 1.1 0.049 12.4 0.1 2.2 2 0 0 2 2 2 2 Peptidase C1-like family RNA_pol_Rpb5_C PF01191.19 OQS02360.1 - 0.18 11.7 0.2 3.5 7.5 0.1 2.4 1 1 1 2 2 2 0 RNA polymerase Rpb5, C-terminal domain HoxA13_N PF12284.8 OQS02360.1 - 1.8 9.2 6.5 7.2 7.3 0.6 2.5 2 1 0 2 2 2 0 Hox protein A13 N terminal CBM_1 PF00734.18 OQS02361.1 - 6.3e-08 32.4 18.6 1e-05 25.4 3.3 3.6 3 1 0 3 3 3 2 Fungal cellulose binding domain CHCH PF06747.13 OQS02361.1 - 1.3 9.2 7.5 3.3 8.0 0.2 3.9 4 1 1 5 5 5 0 CHCH domain FYVE PF01363.21 OQS02362.1 - 2.3e-14 53.3 11.9 7.1e-14 51.7 11.9 1.9 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.16 OQS02362.1 - 0.0023 18.1 5.8 0.0074 16.5 5.8 1.8 1 0 0 1 1 1 1 FYVE-type zinc finger ILVD_EDD PF00920.21 OQS02363.1 - 0 1435.0 3.6 6.4e-216 717.9 1.9 2.0 2 0 0 2 2 2 2 Dehydratase family FeoA PF04023.14 OQS02363.1 - 3.1e-05 24.1 1.3 1.9 8.8 0.0 4.8 6 0 0 6 6 6 3 FeoA domain Lipase_3 PF01764.25 OQS02363.1 - 0.01 15.7 0.0 1 9.2 0.0 2.4 2 0 0 2 2 2 0 Lipase (class 3) Sipho_tail PF05709.11 OQS02363.1 - 0.11 11.9 0.0 2.6 7.4 0.0 2.1 2 0 0 2 2 2 0 Phage tail protein DWNN PF08783.11 OQS02364.1 - 2.9e-25 88.3 0.3 2.9e-25 88.3 0.3 2.4 2 0 0 2 2 2 1 DWNN domain zf-CCHC_2 PF13696.6 OQS02364.1 - 7.3e-09 35.3 1.3 7.3e-09 35.3 1.3 2.7 3 0 0 3 3 3 1 Zinc knuckle zf-C3HC4_2 PF13923.6 OQS02364.1 - 0.00021 21.1 11.0 0.00038 20.3 11.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 OQS02364.1 - 0.0064 16.3 11.4 0.0064 16.3 11.4 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-CCHC PF00098.23 OQS02364.1 - 0.0099 15.9 0.2 0.02 14.9 0.2 1.6 1 0 0 1 1 1 1 Zinc knuckle zf-RING_5 PF14634.6 OQS02364.1 - 0.53 10.3 11.8 1.1 9.3 11.8 1.5 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4 PF00097.25 OQS02364.1 - 0.68 9.9 12.3 1.4 8.9 12.3 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 OQS02364.1 - 1 9.3 10.8 2.2 8.2 10.8 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_6 PF14835.6 OQS02364.1 - 1.2 9.1 4.0 2.4 8.1 4.0 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein DUF667 PF05018.13 OQS02365.1 - 1.6e-12 47.6 0.2 3.5e-09 36.7 0.1 2.0 1 1 1 2 2 2 2 Protein of unknown function (DUF667) ZZ PF00569.17 OQS02366.1 - 1.7e-06 27.7 7.6 3.4e-06 26.8 7.6 1.4 1 0 0 1 1 1 1 Zinc finger, ZZ type Cnd1_N PF12922.7 OQS02366.1 - 0.12 12.2 0.5 0.86 9.4 0.0 2.2 2 0 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1, N-term PRKG1_interact PF15898.5 OQS02367.1 - 0.023 15.6 12.5 0.023 15.6 12.5 3.3 1 1 2 3 3 3 0 cGMP-dependent protein kinase interacting domain Fib_alpha PF08702.10 OQS02367.1 - 0.92 9.7 26.7 0.34 11.1 8.3 3.2 1 1 1 3 3 3 0 Fibrinogen alpha/beta chain family GvpL_GvpF PF06386.11 OQS02367.1 - 1.9 8.3 14.5 6.9 6.5 7.5 2.4 2 1 0 2 2 2 0 Gas vesicle synthesis protein GvpL/GvpF COG2 PF06148.11 OQS02367.1 - 3 7.9 20.7 3 7.9 6.5 3.5 2 2 1 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 OmpH PF03938.14 OQS02367.1 - 5.8 7.2 15.2 9 6.6 1.3 2.4 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) DUF4055 PF13264.6 OQS02367.1 - 7.4 6.7 11.2 0.32 11.2 1.7 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF4055) DUF4201 PF13870.6 OQS02367.1 - 9 6.0 34.6 1.5 8.5 8.1 3.3 2 1 1 3 3 3 0 Domain of unknown function (DUF4201) CENP-F_leu_zip PF10473.9 OQS02367.1 - 9.7 6.2 39.1 0.23 11.5 6.5 3.7 2 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Vps39_1 PF10366.9 OQS02368.1 - 0.033 14.5 0.3 1.9 8.8 0.1 2.6 2 0 0 2 2 2 0 Vacuolar sorting protein 39 domain 1 FtsJ PF01728.19 OQS02369.1 - 8.1e-13 48.9 0.0 2.4e-12 47.3 0.0 1.8 1 1 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_25 PF13649.6 OQS02369.1 - 0.00092 19.9 0.0 0.0042 17.8 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OQS02369.1 - 0.0012 18.7 0.0 0.0033 17.3 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_24 PF13578.6 OQS02369.1 - 0.0043 18.0 0.0 0.013 16.5 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltr_RsmB-F PF01189.17 OQS02369.1 - 0.016 14.9 0.0 0.53 9.9 0.0 2.5 2 1 0 2 2 2 0 16S rRNA methyltransferase RsmB/F Methyltransf_11 PF08241.12 OQS02369.1 - 0.052 14.2 0.0 0.15 12.7 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase domain YabA PF06156.13 OQS02370.1 - 0.33 11.6 4.9 0.34 11.6 4.1 1.4 1 1 0 1 1 1 0 Initiation control protein YabA CxC6 PF18721.1 OQS02371.1 - 0.00037 20.7 24.9 0.05 13.9 6.0 4.1 1 1 3 4 4 4 4 CxC6 like cysteine cluster associated with KDZ transposases CxC6 PF18721.1 OQS02372.1 - 0.0088 16.3 23.1 0.091 13.0 5.9 4.5 1 1 3 4 4 4 4 CxC6 like cysteine cluster associated with KDZ transposases AAA PF00004.29 OQS02373.1 - 3.7e-58 195.6 0.0 1.9e-44 151.3 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 OQS02373.1 - 2.9e-26 91.0 4.5 8.3e-13 47.9 0.3 2.4 2 0 0 2 2 2 2 AAA+ lid domain RuvB_N PF05496.12 OQS02373.1 - 1.6e-05 24.7 0.0 0.0012 18.7 0.0 3.0 2 1 1 3 3 3 1 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 OQS02373.1 - 0.00022 21.4 0.0 0.00042 20.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 OQS02373.1 - 0.00032 20.7 0.1 0.0066 16.5 0.0 3.0 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) Rad17 PF03215.15 OQS02373.1 - 0.00073 19.5 0.0 0.0015 18.4 0.0 1.5 1 0 0 1 1 1 1 Rad17 P-loop domain TIP49 PF06068.13 OQS02373.1 - 0.0089 15.3 0.0 0.015 14.5 0.0 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_16 PF13191.6 OQS02373.1 - 0.0097 16.3 0.1 0.073 13.5 0.1 2.2 1 1 0 1 1 1 1 AAA ATPase domain HEPN_SAV_6107 PF18726.1 OQS02373.1 - 0.03 14.8 0.3 9.9 6.7 0.0 2.5 2 0 0 2 2 2 0 SAV_6107-like HEPN RNA_helicase PF00910.22 OQS02373.1 - 0.19 12.1 0.0 0.38 11.1 0.0 1.5 1 0 0 1 1 1 0 RNA helicase MFS_1 PF07690.16 OQS02375.1 - 0.0033 16.4 0.9 0.54 9.1 0.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2427 PF10348.9 OQS02375.1 - 0.062 13.1 0.7 0.062 13.1 0.7 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF2427) DUF2627 PF11118.8 OQS02375.1 - 0.096 13.3 0.2 0.33 11.5 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2627) Homeobox_KN PF05920.11 OQS02377.1 - 4e-15 55.4 0.6 1.7e-14 53.4 0.1 2.2 2 0 0 2 2 2 1 Homeobox KN domain Homeodomain PF00046.29 OQS02377.1 - 6.8e-11 41.9 2.0 1.4e-10 40.8 2.0 1.6 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 OQS02378.1 - 3.1e-18 65.4 0.0 5.7e-18 64.5 0.0 1.5 1 0 0 1 1 1 1 Homeobox KN domain Homeodomain PF00046.29 OQS02378.1 - 3.3e-10 39.6 0.4 6.1e-10 38.8 0.4 1.5 1 0 0 1 1 1 1 Homeodomain HI0933_like PF03486.14 OQS02378.1 - 0.16 10.7 0.1 0.22 10.2 0.1 1.2 1 0 0 1 1 1 0 HI0933-like protein Meth_synt_2 PF01717.18 OQS02379.1 - 5.8e-143 476.0 0.0 2.2e-137 457.7 0.0 2.2 2 0 0 2 2 2 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.12 OQS02379.1 - 8.8e-94 314.5 0.0 9.7e-88 294.7 0.0 2.4 2 0 0 2 2 2 2 Cobalamin-independent synthase, N-terminal domain GtrA PF04138.14 OQS02380.1 - 0.43 10.8 7.1 0.073 13.3 1.5 2.3 1 1 1 2 2 2 0 GtrA-like protein EMC3_TMCO1 PF01956.16 OQS02382.1 - 1.8e-38 131.9 11.8 2.7e-38 131.4 11.8 1.2 1 0 0 1 1 1 1 Integral membrane protein EMC3/TMCO1-like DUF5326 PF17260.2 OQS02382.1 - 0.1 12.7 0.7 0.1 12.7 0.7 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5326) Ephrin_rec_like PF07699.13 OQS02383.1 - 3e-11 42.9 277.1 0.00029 20.6 9.2 25.1 13 8 11 25 25 25 18 Putative ephrin-receptor like TNFR_c6 PF00020.18 OQS02384.1 - 3.5e-12 46.5 57.1 0.0087 16.4 0.3 10.3 7 2 2 10 10 10 8 TNFR/NGFR cysteine-rich region Ephrin_rec_like PF07699.13 OQS02384.1 - 9e-05 22.2 102.4 0.016 15.0 6.9 11.3 6 1 7 13 13 13 9 Putative ephrin-receptor like Ank_4 PF13637.6 OQS02385.1 - 1.6e-19 70.0 11.3 5.8e-06 26.7 0.1 7.2 4 2 2 7 7 7 5 Ankyrin repeats (many copies) Ank_2 PF12796.7 OQS02385.1 - 2e-18 66.8 19.0 1.1e-07 32.4 2.4 4.8 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OQS02385.1 - 1.1e-14 54.3 15.1 0.012 15.9 0.0 8.7 5 2 5 10 10 10 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQS02385.1 - 9.6e-10 37.9 5.6 3.9 8.4 0.0 8.4 9 0 0 9 9 9 2 Ankyrin repeat Ank PF00023.30 OQS02385.1 - 0.00011 22.5 6.0 21 5.7 1.3 6.9 2 2 0 2 2 2 1 Ankyrin repeat DUF5049 PF16468.5 OQS02385.1 - 0.00035 20.4 3.5 10 6.1 0.1 5.6 4 2 2 6 6 6 1 Domain of unknown function (DUF5049) Glyco_hydro_46 PF01374.18 OQS02387.1 - 1.4e-29 103.3 0.0 6.2e-29 101.1 0.0 1.8 1 1 0 1 1 1 1 Glycosyl hydrolase family 46 Glyco_hydro_80 PF13647.6 OQS02387.1 - 0.051 13.1 0.3 0.11 12.0 0.2 1.5 2 0 0 2 2 2 0 Glycosyl hydrolase family 80 of chitosanase A Ank_2 PF12796.7 OQS02388.1 - 9.3e-32 109.5 4.7 1.5e-12 48.0 0.2 4.0 2 2 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OQS02388.1 - 7.3e-25 86.7 6.2 1.7e-08 34.5 0.0 5.8 2 2 4 6 6 6 5 Ankyrin repeats (many copies) Ank_4 PF13637.6 OQS02388.1 - 7.7e-23 80.6 6.5 3.7e-08 33.8 0.2 5.9 2 2 5 7 7 7 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQS02388.1 - 5.1e-22 75.6 9.6 2.7e-05 24.2 0.0 7.3 7 0 0 7 7 7 4 Ankyrin repeat Ank PF00023.30 OQS02388.1 - 7.8e-21 73.5 9.1 2.2e-06 27.8 0.0 6.2 6 0 0 6 6 6 4 Ankyrin repeat Thg1 PF04446.12 OQS02388.1 - 0.03 14.3 0.0 0.065 13.3 0.0 1.5 1 0 0 1 1 1 0 tRNAHis guanylyltransferase MCPsignal PF00015.21 OQS02388.1 - 0.28 11.0 0.8 0.6 9.9 0.8 1.5 1 0 0 1 1 1 0 Methyl-accepting chemotaxis protein (MCP) signalling domain PKD_channel PF08016.12 OQS02389.1 - 3.4e-36 124.8 13.2 5.7e-36 124.1 13.2 1.2 1 0 0 1 1 1 1 Polycystin cation channel Ion_trans PF00520.31 OQS02389.1 - 2.4e-10 40.1 20.7 2.4e-10 40.1 20.7 1.6 2 0 0 2 2 2 1 Ion transport protein DivIC PF04977.15 OQS02389.1 - 0.12 12.1 0.1 0.45 10.3 0.1 1.9 1 0 0 1 1 1 0 Septum formation initiator SlyX PF04102.12 OQS02389.1 - 0.27 11.9 1.1 0.65 10.7 1.1 1.6 1 0 0 1 1 1 0 SlyX DUF2633 PF11119.8 OQS02389.1 - 0.67 9.9 3.5 2.3 8.2 3.5 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2633) Mg_trans_NIPA PF05653.14 OQS02391.1 - 1.2e-33 116.5 10.7 1.3e-32 113.1 10.7 2.0 1 1 0 1 1 1 1 Magnesium transporter NIPA Fz PF01392.22 OQS02391.1 - 0.00038 21.1 7.5 0.00038 21.1 7.5 1.9 1 1 1 2 2 2 1 Fz domain PUNUT PF16913.5 OQS02391.1 - 0.01 15.1 5.3 0.013 14.7 2.9 2.0 1 1 1 2 2 2 0 Purine nucleobase transmembrane transport EamA PF00892.20 OQS02391.1 - 0.42 10.8 17.7 0.055 13.6 6.9 3.0 2 1 1 3 3 3 0 EamA-like transporter family DUF3687 PF12459.8 OQS02391.1 - 2.1 7.9 4.3 7.2 6.2 4.3 1.9 1 0 0 1 1 1 0 D-Ala-teichoic acid biosynthesis protein HEAT_2 PF13646.6 OQS02392.1 - 8.9e-09 35.6 4.8 0.0033 17.8 0.1 5.9 4 2 1 5 5 5 2 HEAT repeats Cnd1 PF12717.7 OQS02392.1 - 1.7e-05 24.9 17.0 0.3 11.1 0.1 6.8 7 1 1 8 8 8 4 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 OQS02392.1 - 0.003 17.7 6.9 3 8.3 0.0 6.8 8 0 0 8 8 8 1 HEAT repeat Cys_Met_Meta_PP PF01053.20 OQS02393.1 - 6.4e-11 41.4 0.5 5e-10 38.5 0.2 2.5 2 1 0 2 2 2 1 Cys/Met metabolism PLP-dependent enzyme Adeno_PIX PF03955.14 OQS02393.1 - 0.066 13.4 0.6 12 6.1 0.1 3.0 2 0 0 2 2 2 0 Adenovirus hexon-associated protein (IX) CBFD_NFYB_HMF PF00808.23 OQS02394.1 - 7.4e-13 48.6 1.2 1e-12 48.2 0.0 1.8 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone SPX PF03105.19 OQS02394.1 - 0.31 10.9 7.3 0.12 12.2 2.4 2.1 2 0 0 2 2 2 0 SPX domain Kinesin PF00225.23 OQS02395.1 - 1.7e-86 290.2 5.5 3.7e-85 285.8 5.5 2.5 1 1 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 OQS02395.1 - 3.6e-18 65.9 0.4 1e-17 64.5 0.4 1.8 1 0 0 1 1 1 1 Microtubule binding YabA PF06156.13 OQS02395.1 - 0.0024 18.5 7.4 0.0028 18.3 1.8 3.4 3 0 0 3 3 3 1 Initiation control protein YabA PhoH PF02562.16 OQS02395.1 - 0.017 14.6 0.0 0.033 13.7 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein AAA_22 PF13401.6 OQS02395.1 - 0.078 13.3 1.2 0.33 11.2 0.1 2.7 2 2 1 3 3 3 0 AAA domain HALZ PF02183.18 OQS02395.1 - 0.095 12.9 1.3 1.8 8.8 0.2 2.6 2 0 0 2 2 2 0 Homeobox associated leucine zipper Kinesin_assoc PF16183.5 OQS02395.1 - 0.15 12.2 8.1 0.033 14.3 2.0 2.6 2 1 0 3 3 3 0 Kinesin-associated GIT_CC PF16559.5 OQS02395.1 - 0.26 11.2 3.4 1 9.3 1.1 3.1 3 0 0 3 3 3 0 GIT coiled-coil Rho guanine nucleotide exchange factor Lyase_1 PF00206.20 OQS02396.1 - 7.4e-82 275.2 0.0 1.1e-81 274.7 0.0 1.3 1 0 0 1 1 1 1 Lyase ASL_C2 PF14698.6 OQS02396.1 - 1.8e-23 83.0 0.9 1.1e-22 80.5 0.2 2.3 2 0 0 2 2 2 1 Argininosuccinate lyase C-terminal FSH1 PF03959.13 OQS02397.1 - 2.4e-38 131.9 0.0 2.7e-38 131.8 0.0 1.0 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_2 PF02230.16 OQS02397.1 - 0.0024 17.7 0.0 0.0035 17.2 0.0 1.2 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase BAAT_C PF08840.11 OQS02397.1 - 0.04 13.8 0.3 0.067 13.1 0.0 1.4 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal Pre-PUA PF17832.1 OQS02398.1 - 4.4e-23 81.8 0.0 6.3e-23 81.3 0.0 1.2 1 0 0 1 1 1 1 Pre-PUA-like domain PUA PF01472.20 OQS02398.1 - 1.1e-16 60.5 0.1 1.8e-16 59.9 0.1 1.3 1 0 0 1 1 1 1 PUA domain APG17 PF04108.12 OQS02399.1 - 3.7e-20 72.4 8.7 4.2e-13 49.2 3.2 2.1 2 0 0 2 2 2 2 Autophagy protein Apg17 Herpes_UL36 PF03586.13 OQS02399.1 - 0.00032 20.1 0.6 0.00054 19.3 0.6 1.3 1 0 0 1 1 1 1 Herpesvirus UL36 tegument protein TauD PF02668.16 OQS02399.1 - 0.098 12.4 0.4 1.4 8.6 0.0 2.1 1 1 1 2 2 2 0 Taurine catabolism dioxygenase TauD, TfdA family DUF2972 PF11186.8 OQS02399.1 - 0.95 9.3 7.3 0.3 11.0 2.5 2.3 2 1 0 3 3 3 0 Protein of unknown function (DUF2972) Pkinase PF00069.25 OQS02401.1 - 9e-74 248.2 0.0 1.7e-73 247.2 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQS02401.1 - 9.6e-44 149.6 0.0 1.8e-43 148.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase POLO_box PF00659.18 OQS02401.1 - 2.2e-34 117.5 2.6 1.5e-17 63.5 0.3 2.8 2 0 0 2 2 2 2 POLO box duplicated region Kinase-like PF14531.6 OQS02401.1 - 3e-10 39.9 0.0 3e-08 33.4 0.0 2.3 1 1 1 2 2 2 2 Kinase-like Pkinase_fungal PF17667.1 OQS02401.1 - 4.6e-07 29.0 0.0 8.4e-07 28.1 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 OQS02401.1 - 0.00041 20.3 0.4 0.00095 19.2 0.1 1.8 2 0 0 2 2 2 1 Phosphotransferase enzyme family Cofilin_ADF PF00241.20 OQS02402.1 - 2.2e-20 72.7 0.0 3.9e-20 71.9 0.0 1.4 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein Pkinase_Tyr PF07714.17 OQS02402.1 - 0.066 12.5 0.0 0.1 11.8 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase EGF_2 PF07974.13 OQS02404.1 - 4.9e-12 46.0 58.9 1.8e-05 25.0 5.2 5.6 4 1 0 4 4 4 3 EGF-like domain EGF PF00008.27 OQS02404.1 - 0.0056 17.0 50.3 0.02 15.2 3.1 6.0 6 0 0 6 6 6 5 EGF-like domain Laminin_EGF PF00053.24 OQS02404.1 - 4.7 7.4 44.8 0.2 11.8 1.9 4.4 3 1 1 4 4 4 0 Laminin EGF domain RRM_1 PF00076.22 OQS02405.1 - 0.029 14.2 2.7 0.26 11.1 0.0 3.6 4 1 0 4 4 4 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Baculo_PEP_C PF04513.12 OQS02405.1 - 0.6 10.2 13.7 0.39 10.8 1.0 3.6 1 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus RB_A PF01858.17 OQS02405.1 - 2.3 8.0 13.8 2.3 8.0 0.3 3.9 3 1 0 3 3 3 0 Retinoblastoma-associated protein A domain DUF1295 PF06966.12 OQS02406.1 - 1.6e-45 155.5 12.6 2.4e-45 154.9 12.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) ICMT PF04140.14 OQS02406.1 - 0.024 15.1 0.1 0.024 15.1 0.1 2.4 2 0 0 2 2 2 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family EGF_2 PF07974.13 OQS02407.1 - 2.4e-26 91.8 95.6 9.7e-07 29.1 5.1 10.8 10 0 0 10 10 10 9 EGF-like domain EGF PF00008.27 OQS02407.1 - 0.00017 21.8 93.0 0.00058 20.1 1.4 11.2 11 1 0 11 11 11 6 EGF-like domain Laminin_EGF PF00053.24 OQS02407.1 - 0.0099 16.0 4.8 0.0099 16.0 4.8 8.3 7 1 2 9 9 9 5 Laminin EGF domain hEGF PF12661.7 OQS02407.1 - 0.015 15.9 4.1 0.015 15.9 4.1 11.0 11 0 0 11 11 11 0 Human growth factor-like EGF Yippee-Mis18 PF03226.14 OQS02408.1 - 7.1e-22 77.6 0.3 1e-21 77.1 0.3 1.3 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly RIG-I_C-RD PF11648.8 OQS02408.1 - 0.021 15.0 0.0 0.032 14.5 0.0 1.3 1 0 0 1 1 1 0 C-terminal domain of RIG-I ASD2 PF08687.11 OQS02408.1 - 0.048 13.2 0.1 0.081 12.5 0.1 1.4 1 1 0 1 1 1 0 Apx/Shroom domain ASD2 LepB_GAP_N PF18172.1 OQS02408.1 - 0.11 12.4 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 LepB GAP domain N-terminal subdomain YfdX PF10938.8 OQS02409.1 - 0.015 15.3 0.8 0.015 15.3 0.8 1.7 1 1 1 2 2 2 0 YfdX protein Pkinase PF00069.25 OQS02410.1 - 1.5e-54 185.1 0.0 1.8e-54 184.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQS02410.1 - 3.4e-54 183.9 0.0 4.1e-54 183.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 OQS02410.1 - 0.00021 20.7 0.1 0.00039 19.9 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 OQS02410.1 - 0.00057 18.8 0.0 0.00076 18.4 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 OQS02410.1 - 0.0066 16.4 0.0 0.015 15.3 0.0 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family FTA2 PF13095.6 OQS02410.1 - 0.035 13.7 0.0 0.33 10.5 0.0 2.1 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Haspin_kinase PF12330.8 OQS02410.1 - 0.067 12.1 0.0 0.3 10.0 0.0 1.8 1 1 0 1 1 1 0 Haspin like kinase domain NDUFA12 PF05071.16 OQS02411.1 - 8.9e-17 61.7 4.1 8.9e-17 61.7 4.1 1.9 1 1 1 2 2 2 1 NADH ubiquinone oxidoreductase subunit NDUFA12 Pkinase PF00069.25 OQS02412.1 - 1.6e-68 231.0 0.0 2.3e-68 230.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain GTP_cyclohydro2 PF00925.20 OQS02412.1 - 2.6e-54 183.2 0.0 4.2e-54 182.5 0.0 1.3 1 0 0 1 1 1 1 GTP cyclohydrolase II Pkinase_Tyr PF07714.17 OQS02412.1 - 6.8e-30 104.2 0.0 1.2e-29 103.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 OQS02412.1 - 0.016 14.2 0.3 0.05 12.6 0.0 1.9 2 1 0 2 2 2 0 Haspin like kinase domain Kinase-like PF14531.6 OQS02412.1 - 0.017 14.4 0.0 0.035 13.4 0.0 1.5 1 0 0 1 1 1 0 Kinase-like APH PF01636.23 OQS02412.1 - 0.018 15.0 0.1 0.029 14.3 0.1 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 OQS02412.1 - 0.03 13.4 0.0 0.078 12.0 0.0 1.6 2 0 0 2 2 2 0 Seadornavirus VP7 RIO1 PF01163.22 OQS02412.1 - 0.039 13.5 0.0 0.073 12.7 0.0 1.4 1 0 0 1 1 1 0 RIO1 family Kdo PF06293.14 OQS02412.1 - 0.092 12.1 0.3 0.22 10.8 0.3 1.6 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Ribosomal_L17 PF01196.19 OQS02413.1 - 1.8e-34 118.5 0.4 2.2e-34 118.2 0.4 1.1 1 0 0 1 1 1 1 Ribosomal protein L17 DUF872 PF05915.12 OQS02415.1 - 2.6e-15 56.6 0.0 3e-15 56.4 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF872) DUF3040 PF11239.8 OQS02415.1 - 0.0007 19.8 0.1 0.001 19.3 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3040) Pkinase PF00069.25 OQS02417.1 - 2.5e-67 227.0 0.0 5.2e-67 226.0 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQS02417.1 - 1.2e-35 123.1 0.0 4.2e-35 121.3 0.0 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase DEAD PF00270.29 OQS02417.1 - 3.7e-12 46.4 0.0 1.1e-11 44.8 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 OQS02417.1 - 4.4e-06 26.8 0.0 5.5e-05 23.2 0.0 2.5 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Kdo PF06293.14 OQS02417.1 - 9.2e-06 25.2 0.5 2.2e-05 23.9 0.5 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 OQS02417.1 - 0.0015 17.4 0.9 0.0031 16.3 0.0 1.9 2 0 0 2 2 2 1 Fungal protein kinase RIO1 PF01163.22 OQS02417.1 - 0.0021 17.7 0.4 0.0052 16.4 0.4 1.6 1 0 0 1 1 1 1 RIO1 family Kinase-like PF14531.6 OQS02417.1 - 0.028 13.7 0.1 0.073 12.4 0.0 1.7 2 0 0 2 2 2 0 Kinase-like PH PF00169.29 OQS02417.1 - 0.034 14.7 0.0 0.12 12.9 0.0 2.0 1 0 0 1 1 1 0 PH domain T2SSE PF00437.20 OQS02417.1 - 0.13 11.3 0.0 0.28 10.2 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein APH PF01636.23 OQS02417.1 - 0.31 10.9 2.0 0.27 11.1 0.2 1.8 2 0 0 2 2 2 0 Phosphotransferase enzyme family Apolipoprotein PF01442.18 OQS02418.1 - 3.1e-07 30.5 18.2 3.7e-07 30.2 18.2 1.1 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain DUF4954 PF16314.5 OQS02418.1 - 0.0082 14.3 2.7 0.01 14.0 2.7 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4954) Peptidase_M75 PF09375.10 OQS02418.1 - 0.0083 15.6 3.6 0.0083 15.6 3.6 2.5 1 1 2 3 3 3 1 Imelysin YtxH PF12732.7 OQS02418.1 - 0.013 16.0 21.0 12 6.5 6.6 3.1 1 1 1 2 2 2 0 YtxH-like protein OmpH PF03938.14 OQS02418.1 - 0.015 15.6 5.3 0.015 15.6 5.3 2.1 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) Spectrin PF00435.21 OQS02418.1 - 0.031 14.8 4.0 0.031 14.8 4.0 2.2 2 0 0 2 2 2 0 Spectrin repeat ApoLp-III PF07464.11 OQS02418.1 - 0.033 14.3 23.0 0.047 13.8 19.9 2.2 1 1 1 2 2 2 0 Apolipophorin-III precursor (apoLp-III) DUF1664 PF07889.12 OQS02418.1 - 0.033 14.2 12.0 0.72 9.9 0.6 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) SF-assemblin PF06705.11 OQS02418.1 - 0.044 13.1 11.2 0.21 10.9 11.2 1.9 1 1 0 1 1 1 0 SF-assemblin/beta giardin Cor1 PF04803.12 OQS02418.1 - 0.058 13.6 11.8 0.12 12.6 6.7 2.2 2 0 0 2 2 2 0 Cor1/Xlr/Xmr conserved region GldM_C PF12080.8 OQS02418.1 - 0.11 12.8 2.8 0.2 11.9 0.5 2.1 1 1 1 2 2 2 0 GldM C-terminal domain Baculo_PEP_C PF04513.12 OQS02418.1 - 0.12 12.5 13.1 1.5 8.8 10.0 2.6 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus KapB PF08810.10 OQS02418.1 - 0.12 12.5 7.6 0.32 11.2 0.5 3.0 2 1 1 3 3 3 0 Kinase associated protein B Carbpep_Y_N PF05388.11 OQS02418.1 - 0.14 12.7 8.5 0.093 13.3 5.3 2.1 1 1 1 2 2 2 0 Carboxypeptidase Y pro-peptide Prominin PF05478.11 OQS02418.1 - 0.16 9.9 6.6 0.21 9.5 6.6 1.2 1 0 0 1 1 1 0 Prominin DUF4407 PF14362.6 OQS02418.1 - 0.2 11.0 18.5 0.28 10.5 18.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF883 PF05957.13 OQS02418.1 - 0.27 11.8 17.2 0.72 10.5 2.4 3.0 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF883) AAA_13 PF13166.6 OQS02418.1 - 0.3 9.7 17.6 0.53 8.9 17.6 1.4 1 1 0 1 1 1 0 AAA domain DUF1863 PF08937.11 OQS02418.1 - 0.31 11.4 3.8 0.23 11.8 0.7 2.0 2 0 0 2 2 2 0 MTH538 TIR-like domain (DUF1863) T3SS_needle_F PF09392.10 OQS02418.1 - 0.31 11.2 11.9 6.3 7.1 0.1 4.2 1 1 4 5 5 5 0 Type III secretion needle MxiH, YscF, SsaG, EprI, PscF, EscF DUF3584 PF12128.8 OQS02418.1 - 0.35 8.3 15.6 0.45 8.0 15.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF4404 PF14357.6 OQS02418.1 - 0.42 11.3 14.4 1.2 9.8 5.0 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF4404) Csa1 PF06023.12 OQS02418.1 - 0.64 9.3 3.1 2.8 7.2 0.1 1.9 1 1 1 2 2 2 0 CRISPR-associated exonuclease Csa1 Muted PF14942.6 OQS02418.1 - 0.65 10.3 13.2 0.38 11.1 10.0 1.9 1 1 1 2 2 2 0 Organelle biogenesis, Muted-like protein CdvA PF18822.1 OQS02418.1 - 0.78 9.6 10.2 0.9 9.4 2.3 3.1 1 1 2 3 3 3 0 CdvA-like coiled-coil domain DUF3510 PF12022.8 OQS02418.1 - 0.92 9.9 11.7 1.8 8.9 4.8 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF3510) TMPIT PF07851.13 OQS02418.1 - 0.93 8.7 9.1 1.2 8.3 9.1 1.1 1 0 0 1 1 1 0 TMPIT-like protein CSN5_C PF18323.1 OQS02418.1 - 1.1 10.2 12.5 4.1 8.4 1.8 3.0 1 1 2 3 3 3 0 Cop9 signalosome subunit 5 C-terminal domain THOC7 PF05615.13 OQS02418.1 - 1.7 8.9 16.4 0.92 9.8 6.8 2.1 1 1 1 2 2 2 0 Tho complex subunit 7 Brr6_like_C_C PF10104.9 OQS02418.1 - 1.9 8.3 4.8 7.7 6.3 0.8 2.2 1 1 0 2 2 2 0 Di-sulfide bridge nucleocytoplasmic transport domain RB_A PF01858.17 OQS02418.1 - 2 8.2 10.2 12 5.6 7.0 2.7 1 1 1 2 2 2 0 Retinoblastoma-associated protein A domain DASH_Spc19 PF08287.11 OQS02418.1 - 3.8 7.4 12.1 1.9 8.4 7.6 2.0 1 1 1 2 2 2 0 Spc19 Phasin PF05597.11 OQS02418.1 - 4 7.5 12.5 3.1 7.8 8.2 2.5 1 1 1 2 2 2 0 Poly(hydroxyalcanoate) granule associated protein (phasin) PLC-beta_C PF08703.10 OQS02418.1 - 4.6 7.2 16.1 1.6 8.7 4.9 2.6 1 1 1 2 2 2 0 PLC-beta C terminal PRKCSH-like PF12999.7 OQS02418.1 - 8 6.2 8.5 1.6 8.5 2.1 2.0 1 1 1 2 2 2 0 Glucosidase II beta subunit-like ZYG-11_interact PF05884.12 OQS02418.1 - 8.7 5.7 11.4 2.6 7.4 2.6 2.3 1 1 1 2 2 2 0 Interactor of ZYG-11 PHO4 PF01384.20 OQS02419.1 - 1.7e-31 109.5 12.8 3.9e-31 108.3 12.7 1.4 1 1 0 1 1 1 1 Phosphate transporter family YbgT_YccB PF08173.11 OQS02419.1 - 7.9 6.7 9.2 4.5 7.5 0.8 3.3 2 0 0 2 2 2 0 Membrane bound YbgT-like protein Apolipoprotein PF01442.18 OQS02420.1 - 0.031 14.1 6.4 0.044 13.6 6.4 1.2 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain Baculo_PEP_C PF04513.12 OQS02420.1 - 0.038 14.0 5.4 0.085 12.9 4.6 1.8 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus UpxZ PF06603.11 OQS02420.1 - 0.068 13.5 0.2 0.11 12.7 0.2 1.4 1 0 0 1 1 1 0 UpxZ family of transcription anti-terminator antagonists TypeIII_RM_meth PF12564.8 OQS02420.1 - 0.11 12.7 0.5 6.9 6.9 0.0 2.2 2 0 0 2 2 2 0 Type III restriction/modification enzyme methylation subunit PH PF00169.29 OQS02421.1 - 3.5e-09 37.1 0.1 6.6e-09 36.2 0.1 1.5 1 1 0 1 1 1 1 PH domain PH_8 PF15409.6 OQS02421.1 - 7e-05 23.0 0.8 0.00025 21.3 0.8 1.8 1 1 0 1 1 1 1 Pleckstrin homology domain PH_11 PF15413.6 OQS02421.1 - 0.0022 18.4 1.6 0.032 14.6 1.6 2.2 1 1 0 1 1 1 1 Pleckstrin homology domain PH_17 PF18012.1 OQS02421.1 - 0.049 13.4 0.1 0.19 11.5 0.0 1.9 2 0 0 2 2 2 0 PH domain Ank_4 PF13637.6 OQS02422.1 - 1.9e-06 28.3 0.0 0.00016 22.1 0.0 2.5 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 OQS02422.1 - 7e-06 26.5 0.0 0.16 12.5 0.0 2.3 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OQS02422.1 - 0.0019 18.5 0.0 35 5.4 0.0 4.0 4 0 0 4 4 4 1 Ankyrin repeat Peptidase_C48 PF02902.19 OQS02423.1 - 6.3e-27 94.8 1.9 8.7e-27 94.4 0.7 1.9 2 0 0 2 2 2 1 Ulp1 protease family, C-terminal catalytic domain DUF2627 PF11118.8 OQS02425.1 - 0.027 15.0 0.0 0.036 14.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2627) Nuc_sug_transp PF04142.15 OQS02426.1 - 1.5e-43 149.2 27.8 9.4e-43 146.6 27.8 2.0 1 1 0 1 1 1 1 Nucleotide-sugar transporter DnaJ PF00226.31 OQS02426.1 - 3.5e-28 97.5 1.9 3.7e-25 87.8 0.6 2.6 2 0 0 2 2 2 2 DnaJ domain Halo_GVPC PF05465.13 OQS02426.1 - 0.054 13.8 0.6 0.1 12.9 0.6 1.4 1 0 0 1 1 1 0 Halobacterial gas vesicle protein C (GVPC) repeat Catalase-rel PF06628.12 OQS02426.1 - 0.12 12.7 0.0 0.42 10.8 0.0 2.0 1 0 0 1 1 1 0 Catalase-related immune-responsive EamA PF00892.20 OQS02426.1 - 3.7 7.7 32.8 0.043 14.0 8.8 2.7 2 1 0 2 2 2 0 EamA-like transporter family Methyltransf_16 PF10294.9 OQS02427.1 - 2.2e-11 43.8 0.1 9.5e-11 41.7 0.1 1.8 1 1 0 1 1 1 1 Lysine methyltransferase Methyltransf_25 PF13649.6 OQS02427.1 - 7.3e-05 23.4 0.1 0.00075 20.2 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 OQS02427.1 - 0.00052 19.6 0.0 0.00095 18.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.13 OQS02427.1 - 0.001 18.6 0.0 0.0015 18.0 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_31 PF13847.6 OQS02427.1 - 0.0029 17.4 0.0 0.0054 16.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OQS02427.1 - 0.0057 17.3 0.0 0.015 15.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OQS02427.1 - 0.012 16.3 0.1 0.038 14.7 0.0 1.9 2 1 0 2 2 2 0 Methyltransferase domain Methyltransf_9 PF08003.11 OQS02427.1 - 0.047 12.6 0.0 0.063 12.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) tRNA_U5-meth_tr PF05958.11 OQS02427.1 - 0.048 12.7 0.0 0.067 12.2 0.0 1.2 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase PCMT PF01135.19 OQS02427.1 - 0.063 13.0 0.0 0.16 11.7 0.0 1.6 1 1 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_23 PF13489.6 OQS02427.1 - 0.084 12.7 0.0 0.14 12.0 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain Sec1 PF00995.23 OQS02428.1 - 7e-106 355.7 1.9 8.6e-106 355.4 1.9 1.0 1 0 0 1 1 1 1 Sec1 family Las1 PF04031.13 OQS02429.1 - 8.2e-44 149.4 4.5 1.3e-43 148.8 4.5 1.3 1 0 0 1 1 1 1 Las1-like MMtag PF10159.9 OQS02430.1 - 4.1e-31 107.1 2.5 4.1e-31 107.1 2.5 2.7 2 1 0 2 2 2 1 Multiple myeloma tumor-associated GAGA_bind PF06217.12 OQS02430.1 - 0.063 13.6 12.7 0.077 13.3 12.7 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family DUF1509 PF07420.11 OQS02430.1 - 0.32 9.9 13.3 0.5 9.3 13.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1509) FmiP_Thoc5 PF09766.9 OQS02430.1 - 3.1 7.0 15.8 5.2 6.2 15.8 1.3 1 0 0 1 1 1 0 Fms-interacting protein/Thoc5 RR_TM4-6 PF06459.12 OQS02430.1 - 3.5 7.4 23.6 7.4 6.3 23.6 1.5 1 1 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF913 PF06025.12 OQS02430.1 - 5.7 5.8 6.2 5.9 5.8 6.2 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) EIIBC-GUT_N PF03612.14 OQS02430.1 - 6 6.6 8.5 12 5.6 8.5 1.5 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus TMEM214 PF10151.9 OQS02430.1 - 8.3 4.7 10.1 9.4 4.5 10.1 1.1 1 0 0 1 1 1 0 TMEM214, C-terminal, caspase 4 activator Jak1_Phl PF17887.1 OQS02430.1 - 9.7 6.1 14.0 18 5.2 13.4 1.8 1 1 0 1 1 1 0 Jak1 pleckstrin homology-like domain Ribonuclease_T2 PF00445.18 OQS02431.1 - 2.1e-24 86.8 0.7 3.1e-24 86.2 0.7 1.2 1 0 0 1 1 1 1 Ribonuclease T2 family Ald_Xan_dh_C2 PF02738.18 OQS02432.1 - 6.4e-196 652.1 3.7 9e-196 651.6 3.7 1.1 1 0 0 1 1 1 1 Molybdopterin-binding domain of aldehyde dehydrogenase DREV PF05219.12 OQS02432.1 - 1.6e-55 188.1 0.0 2.8e-55 187.3 0.0 1.4 1 0 0 1 1 1 1 DREV methyltransferase FAD_binding_5 PF00941.21 OQS02432.1 - 2.7e-46 157.4 0.1 5.2e-46 156.5 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain in molybdopterin dehydrogenase Ald_Xan_dh_C PF01315.22 OQS02432.1 - 8.9e-28 96.9 1.4 2e-27 95.7 1.4 1.6 1 0 0 1 1 1 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain Fer2_2 PF01799.20 OQS02432.1 - 1.7e-27 95.3 0.3 5.4e-27 93.6 0.3 2.0 1 0 0 1 1 1 1 [2Fe-2S] binding domain CO_deh_flav_C PF03450.17 OQS02432.1 - 2.7e-24 85.3 0.0 9.1e-24 83.6 0.0 1.9 1 0 0 1 1 1 1 CO dehydrogenase flavoprotein C-terminal domain Pkinase PF00069.25 OQS02432.1 - 6.4e-20 71.6 0.0 1.7e-19 70.2 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQS02432.1 - 1e-12 47.9 0.0 2.3e-12 46.8 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Fer2 PF00111.27 OQS02432.1 - 6.4e-09 35.6 0.7 6.4e-09 35.6 0.7 2.5 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Methyltransf_23 PF13489.6 OQS02432.1 - 6.4e-09 35.8 0.0 1.8e-08 34.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OQS02432.1 - 1.8e-05 25.4 0.0 5.5e-05 23.8 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OQS02432.1 - 0.0014 19.2 0.0 0.0054 17.4 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OQS02432.1 - 0.021 15.5 0.0 0.11 13.3 0.0 2.3 2 0 0 2 2 1 0 Methyltransferase domain Kinesin PF00225.23 OQS02433.1 - 2.1e-59 201.1 2.3 3.4e-59 200.4 2.3 1.3 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 OQS02433.1 - 1.3e-13 51.2 0.1 3.3e-13 49.8 0.1 1.7 1 0 0 1 1 1 1 Microtubule binding AAA_11 PF13086.6 OQS02433.1 - 0.0013 18.5 0.1 0.0022 17.8 0.1 1.5 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 OQS02433.1 - 0.025 14.9 0.0 0.057 13.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain SRP54 PF00448.22 OQS02433.1 - 0.042 13.5 0.9 6.9 6.2 0.1 2.4 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_24 PF13479.6 OQS02433.1 - 0.061 13.0 0.1 0.15 11.8 0.1 1.7 1 1 0 1 1 1 0 AAA domain NACHT PF05729.12 OQS02433.1 - 0.073 13.0 0.2 5.6 6.9 0.1 2.4 2 0 0 2 2 2 0 NACHT domain DUF5601 PF18151.1 OQS02433.1 - 0.076 13.3 0.0 0.63 10.4 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF5601) PX PF00787.24 OQS02434.1 - 1.1e-08 35.1 0.0 2.3e-08 34.0 0.0 1.5 1 0 0 1 1 1 1 PX domain LMBR1 PF04791.16 OQS02435.1 - 6.4e-10 38.6 25.5 1.1e-09 37.8 6.6 2.1 1 1 1 2 2 2 2 LMBR1-like membrane protein GCV_H PF01597.19 OQS02436.1 - 8.6e-44 148.3 0.1 9.8e-44 148.2 0.1 1.0 1 0 0 1 1 1 1 Glycine cleavage H-protein RnfC_N PF13375.6 OQS02436.1 - 0.0038 17.2 0.0 0.0057 16.6 0.0 1.2 1 0 0 1 1 1 1 RnfC Barrel sandwich hybrid domain Biotin_lipoyl PF00364.22 OQS02436.1 - 0.01 15.7 0.1 0.017 14.9 0.1 1.3 1 0 0 1 1 1 1 Biotin-requiring enzyme His_Phos_2 PF00328.22 OQS02437.1 - 7.7e-16 58.4 0.0 3.1e-08 33.4 0.1 2.8 1 1 0 2 2 2 2 Histidine phosphatase superfamily (branch 2) DSPc PF00782.20 OQS02438.1 - 9.4e-35 119.3 0.1 1.7e-13 50.6 0.0 3.8 3 0 0 3 3 3 3 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 OQS02438.1 - 2.4e-07 30.6 0.0 0.22 11.1 0.0 3.5 3 0 0 3 3 3 3 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 OQS02438.1 - 0.00047 20.2 0.0 0.93 9.4 0.0 3.2 3 0 0 3 3 3 2 Tyrosine phosphatase family LRR_8 PF13855.6 OQS02438.1 - 0.00057 19.6 17.8 0.028 14.2 1.3 4.1 1 1 3 4 4 4 3 Leucine rich repeat LRR_6 PF13516.6 OQS02438.1 - 0.074 13.1 7.4 6.1 7.2 0.1 4.7 4 0 0 4 4 4 0 Leucine Rich repeat LRR_4 PF12799.7 OQS02438.1 - 1.7 9.2 19.5 0.057 13.9 0.9 4.6 2 1 1 4 4 4 0 Leucine Rich repeats (2 copies) LNS2 PF08235.13 OQS02439.1 - 1.8e-25 89.7 0.0 3.9e-13 49.4 0.0 2.2 1 1 1 2 2 2 2 LNS2 (Lipin/Ned1/Smp2) Lipin_N PF04571.14 OQS02439.1 - 1.3e-16 60.4 0.8 2.8e-16 59.3 0.8 1.5 1 0 0 1 1 1 1 lipin, N-terminal conserved region Lipin_mid PF16876.5 OQS02439.1 - 3.7e-07 30.2 0.0 7.4e-07 29.3 0.0 1.5 1 0 0 1 1 1 1 Lipin/Ned1/Smp2 multi-domain protein middle domain ABC_sub_bind PF04392.12 OQS02439.1 - 0.012 14.8 0.0 0.018 14.3 0.0 1.2 1 0 0 1 1 1 0 ABC transporter substrate binding protein Dcc1 PF09724.9 OQS02440.1 - 7.4e-75 252.3 0.4 1.2e-74 251.6 0.4 1.3 1 0 0 1 1 1 1 Sister chromatid cohesion protein Dcc1 Ribosomal_L18A PF01775.17 OQS02440.1 - 6.7e-52 174.7 0.2 1.3e-51 173.8 0.2 1.5 1 0 0 1 1 1 1 Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A W2 PF02020.18 OQS02440.1 - 2.5e-11 43.6 1.6 1.1e-10 41.5 1.6 2.1 1 0 0 1 1 1 1 eIF4-gamma/eIF5/eIF2-epsilon NTP_transferase PF00483.23 OQS02440.1 - 1.3e-08 34.8 0.2 2.4e-08 33.8 0.2 1.4 1 0 0 1 1 1 1 Nucleotidyl transferase Hexapep PF00132.24 OQS02440.1 - 9.5e-06 25.1 17.2 0.0017 18.0 1.9 3.3 2 1 0 2 2 2 2 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.7 OQS02440.1 - 0.00084 19.7 0.0 0.0017 18.7 0.0 1.4 1 0 0 1 1 1 1 MobA-like NTP transferase domain DUF4954 PF16314.5 OQS02440.1 - 0.0075 14.5 4.1 0.024 12.8 0.3 2.2 1 1 1 2 2 2 2 Domain of unknown function (DUF4954) Hexapep_2 PF14602.6 OQS02440.1 - 0.6 9.9 10.5 1.6 8.5 0.6 3.2 1 1 1 2 2 2 0 Hexapeptide repeat of succinyl-transferase Ank_3 PF13606.6 OQS02441.1 - 2e-12 46.1 0.1 7.4e-06 25.9 0.2 3.6 3 0 0 3 3 3 2 Ankyrin repeat Ank_2 PF12796.7 OQS02441.1 - 2e-12 47.5 0.0 4.6e-12 46.4 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQS02441.1 - 2.4e-11 43.9 0.5 6.6e-06 26.6 0.1 3.1 1 1 2 3 3 3 3 Ankyrin repeats (many copies) C2 PF00168.30 OQS02441.1 - 5.7e-10 39.4 0.0 1.3e-09 38.3 0.0 1.7 1 0 0 1 1 1 1 C2 domain Ank PF00023.30 OQS02441.1 - 1.9e-09 37.6 0.9 9.5e-05 22.7 1.1 4.2 4 0 0 4 4 4 1 Ankyrin repeat WW PF00397.26 OQS02441.1 - 1.2e-07 31.7 0.7 3.3e-07 30.3 0.7 1.8 1 0 0 1 1 1 1 WW domain Ank_5 PF13857.6 OQS02441.1 - 5.8e-07 29.7 0.1 0.0011 19.2 0.1 2.9 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Aida_C2 PF14186.6 OQS02441.1 - 0.0014 18.3 0.0 0.0029 17.2 0.0 1.5 1 0 0 1 1 1 1 Cytoskeletal adhesion IQ PF00612.27 OQS02441.1 - 0.011 15.4 0.2 0.04 13.7 0.2 2.1 1 0 0 1 1 1 0 IQ calmodulin-binding motif PRANC PF09372.10 OQS02441.1 - 0.14 12.5 1.4 0.43 10.9 0.0 2.5 3 0 0 3 3 3 0 PRANC domain Cellulase PF00150.18 OQS02442.1 - 8.7e-25 87.7 0.7 1.2e-24 87.3 0.7 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Cpn60_TCP1 PF00118.24 OQS02443.1 - 6.5e-154 513.2 10.3 7.4e-154 513.0 10.3 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family SHIPPO-rpt PF07004.12 OQS02444.1 - 0.0041 18.0 0.2 0.8 10.7 0.1 3.1 2 0 0 2 2 2 2 Sperm-tail PG-rich repeat His_Phos_1 PF00300.22 OQS02445.1 - 3.1e-49 167.3 0.0 3.4e-49 167.2 0.0 1.0 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) DUF4972 PF16342.5 OQS02445.1 - 0.079 12.7 0.0 0.17 11.6 0.0 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4972) Myosin_head PF00063.21 OQS02446.1 - 2.6e-94 316.8 0.1 4.7e-94 315.9 0.1 1.3 1 0 0 1 1 1 1 Myosin head (motor domain) WD40 PF00400.32 OQS02446.1 - 6.4e-31 105.9 28.5 3.7e-05 24.4 0.2 11.3 10 0 0 10 10 10 9 WD domain, G-beta repeat MyTH4 PF00784.17 OQS02446.1 - 4.4e-23 81.8 0.0 2.6e-22 79.3 0.0 2.5 1 0 0 1 1 1 1 MyTH4 domain Glyco_hydro_17 PF00332.18 OQS02446.1 - 1.7e-16 60.7 22.1 1.8e-06 27.8 1.8 4.1 4 0 0 4 4 4 3 Glycosyl hydrolases family 17 ANAPC4_WD40 PF12894.7 OQS02446.1 - 1.6e-14 54.0 0.2 3.8e-05 23.9 0.0 6.8 4 1 1 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain zf-LYAR PF08790.11 OQS02446.1 - 1e-12 47.7 2.0 1e-12 47.7 2.0 2.5 2 0 0 2 2 2 1 LYAR-type C2HC zinc finger Utp12 PF04003.12 OQS02446.1 - 9.8e-11 41.9 2.6 5.8e-10 39.4 2.6 2.4 1 0 0 1 1 1 1 Dip2/Utp12 Family PAN_4 PF14295.6 OQS02446.1 - 8e-10 38.5 13.0 0.00056 19.8 1.1 4.0 3 0 0 3 3 3 3 PAN domain FERM_M PF00373.18 OQS02446.1 - 3e-07 30.9 0.0 1.4e-06 28.7 0.0 2.2 1 0 0 1 1 1 1 FERM central domain AAA_22 PF13401.6 OQS02446.1 - 0.0015 18.8 0.1 0.72 10.1 0.0 3.1 2 0 0 2 2 2 1 AAA domain ABC_tran PF00005.27 OQS02446.1 - 0.067 13.7 0.1 0.96 10.0 0.0 2.8 2 0 0 2 2 2 0 ABC transporter AAA_16 PF13191.6 OQS02446.1 - 0.07 13.5 0.0 0.36 11.2 0.0 2.2 1 0 0 1 1 1 0 AAA ATPase domain UTP15_C PF09384.10 OQS02446.1 - 0.32 10.7 3.2 9.5 5.9 0.3 3.1 2 0 0 2 2 2 0 UTP15 C terminal Cyt-b5 PF00173.28 OQS02447.1 - 1.1e-08 35.1 0.4 2.4e-08 34.0 0.4 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Anoctamin PF04547.12 OQS02448.1 - 0 1181.7 93.4 3.1e-111 372.4 20.2 5.1 4 1 1 5 5 5 5 Calcium-activated chloride channel Anoct_dimer PF16178.5 OQS02448.1 - 4.4e-19 69.1 0.4 2.5e-05 24.1 0.0 3.6 3 0 0 3 3 3 3 Dimerisation domain of Ca+-activated chloride-channel, anoctamin 7tm_1 PF00001.21 OQS02448.1 - 4.5e-06 26.2 1.4 0.51 9.6 1.2 4.6 5 1 0 5 5 5 2 7 transmembrane receptor (rhodopsin family) RSN1_7TM PF02714.15 OQS02448.1 - 6.6e-05 22.4 38.5 0.38 10.0 0.7 5.3 4 1 0 4 4 4 4 Calcium-dependent channel, 7TM region, putative phosphate DUF2207 PF09972.9 OQS02448.1 - 0.083 11.6 32.3 0.33 9.7 0.1 6.7 6 1 1 7 7 7 0 Predicted membrane protein (DUF2207) XS PF03468.14 OQS02448.1 - 0.54 10.6 13.2 1.1 9.5 0.3 4.3 4 0 0 4 4 4 0 XS domain Dabb PF07876.12 OQS02449.1 - 3.3e-17 62.9 0.1 3.7e-17 62.8 0.1 1.0 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain DUF3859 PF12975.7 OQS02449.1 - 0.13 12.3 0.0 0.15 12.0 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3859) THF_DHG_CYH PF00763.23 OQS02450.1 - 4.4e-22 78.5 0.0 1.8e-21 76.5 0.0 1.9 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain THF_DHG_CYH_C PF02882.19 OQS02450.1 - 2.4e-15 56.2 0.6 3.2e-14 52.6 0.6 2.5 1 1 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain DpaA_N PF16924.5 OQS02450.1 - 0.019 15.1 0.0 0.035 14.2 0.0 1.4 1 0 0 1 1 1 0 Dipicolinate synthase subunit A N-terminal domain XdhC_C PF13478.6 OQS02450.1 - 0.11 13.0 0.0 0.19 12.3 0.0 1.3 1 0 0 1 1 1 0 XdhC Rossmann domain Ribosomal_L28e PF01778.17 OQS02451.1 - 1.1e-27 97.1 2.0 1.1e-27 97.1 2.0 1.3 2 0 0 2 2 2 1 Ribosomal L28e protein family DUF881 PF05949.12 OQS02451.1 - 0.069 13.0 0.1 0.086 12.7 0.1 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF881) Macro PF01661.21 OQS02452.1 - 5.4e-15 55.5 0.0 9.2e-15 54.7 0.0 1.4 1 0 0 1 1 1 1 Macro domain QRPTase_N PF02749.16 OQS02452.1 - 0.046 13.8 0.1 0.14 12.3 0.0 1.8 2 0 0 2 2 2 0 Quinolinate phosphoribosyl transferase, N-terminal domain Pro-kuma_activ PF09286.11 OQS02453.1 - 6.3e-23 81.6 0.0 2e-22 80.0 0.0 1.8 2 0 0 2 2 2 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 OQS02453.1 - 1.8e-06 27.4 0.5 2.9e-06 26.8 0.5 1.2 1 0 0 1 1 1 1 Subtilase family DUF5305 PF17231.2 OQS02453.1 - 0.014 14.8 0.2 0.03 13.7 0.2 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5305) DUF995 PF06191.12 OQS02453.1 - 0.076 12.7 0.1 0.19 11.4 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF995) DUF1242 PF06842.12 OQS02453.1 - 0.27 11.1 1.4 0.68 9.8 1.4 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1242) Pox_A_type_inc PF04508.12 OQS02454.1 - 5.9 6.9 15.7 8.5 6.4 0.3 6.1 5 0 0 5 5 5 0 Viral A-type inclusion protein repeat Pkinase PF00069.25 OQS02455.1 - 3.8e-70 236.3 0.0 5.7e-70 235.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQS02455.1 - 1.8e-37 129.0 0.0 3.2e-37 128.2 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Arb2 PF09757.9 OQS02455.1 - 2.9e-06 26.6 0.0 9.2e-06 25.0 0.0 1.8 1 1 0 1 1 1 1 Arb2 domain Kinase-like PF14531.6 OQS02455.1 - 2.6e-05 23.7 0.0 8.1e-05 22.1 0.0 1.8 2 0 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 OQS02455.1 - 0.0011 18.0 0.1 0.0019 17.2 0.1 1.3 1 0 0 1 1 1 1 Haspin like kinase domain FTA2 PF13095.6 OQS02455.1 - 0.0063 16.2 0.1 0.3 10.7 0.0 2.2 2 0 0 2 2 2 1 Kinetochore Sim4 complex subunit FTA2 Pkinase_fungal PF17667.1 OQS02455.1 - 0.047 12.5 0.0 0.078 11.7 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase FHA PF00498.26 OQS02456.1 - 5.1e-07 29.9 0.0 1.6e-06 28.3 0.0 1.9 1 0 0 1 1 1 1 FHA domain PLATZ PF04640.14 OQS02457.1 - 0.037 14.7 2.9 0.07 13.8 2.9 1.5 1 0 0 1 1 1 0 PLATZ transcription factor DUF2152 PF10222.9 OQS02458.1 - 0.082 11.2 0.9 0.13 10.5 0.7 1.4 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2152) DUF349 PF03993.12 OQS02458.1 - 0.17 12.2 9.5 0.21 11.9 3.1 2.5 2 0 0 2 2 2 0 Domain of Unknown Function (DUF349) DUF572 PF04502.13 OQS02458.1 - 0.77 9.3 5.8 1.1 8.8 5.8 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF572) SpoIIE PF07228.12 OQS02459.1 - 8.5e-08 32.3 0.0 1.5e-07 31.5 0.0 1.4 1 0 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.6 OQS02459.1 - 4.5e-07 29.7 0.1 7e-07 29.1 0.1 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C PF00481.21 OQS02459.1 - 0.0019 17.9 0.0 0.0078 15.9 0.0 1.8 2 0 0 2 2 2 1 Protein phosphatase 2C Myb_Cef PF11831.8 OQS02460.1 - 4.8e-30 104.9 5.1 4.8e-30 104.9 5.1 4.4 3 2 0 4 4 4 1 pre-mRNA splicing factor component Myb_DNA-binding PF00249.31 OQS02460.1 - 1.7e-21 76.1 6.4 1.8e-11 44.0 1.5 2.7 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OQS02460.1 - 1.5e-19 70.0 7.5 7.7e-13 48.5 3.4 2.8 1 1 1 2 2 2 2 Myb-like DNA-binding domain Fungal_TACC PF12709.7 OQS02460.1 - 0.16 12.4 4.6 1 9.8 0.2 4.0 2 1 1 3 3 3 0 Fungal Transforming acidic coiled-coil (TACC) proteins Rap1_C PF11626.8 OQS02460.1 - 6.4 6.9 6.0 0.71 10.0 0.1 2.5 2 0 0 2 2 2 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain LRR_8 PF13855.6 OQS02461.1 - 6.5e-17 61.1 20.6 3.7e-11 42.6 7.6 3.4 2 1 1 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 OQS02461.1 - 8.9e-11 41.9 18.9 0.00049 20.4 1.7 3.9 1 1 1 3 3 3 3 Leucine Rich repeats (2 copies) NRDE-2 PF08424.10 OQS02461.1 - 6.5e-10 38.6 0.8 1.3e-09 37.6 0.4 1.8 1 1 0 1 1 1 1 NRDE-2, necessary for RNA interference zf-C3H1 PF10650.9 OQS02461.1 - 4.2e-07 29.6 3.8 9.5e-07 28.4 3.8 1.6 1 0 0 1 1 1 1 Putative zinc-finger domain LRR_1 PF00560.33 OQS02461.1 - 0.0069 16.8 19.6 11 7.1 0.4 6.7 6 0 0 6 6 6 2 Leucine Rich Repeat LRR_9 PF14580.6 OQS02461.1 - 0.012 15.1 3.3 0.041 13.4 3.1 1.9 1 1 1 2 2 2 0 Leucine-rich repeat TPR_19 PF14559.6 OQS02461.1 - 0.031 14.8 2.4 2.3 8.8 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_11 PF13414.6 OQS02461.1 - 0.031 13.9 0.5 0.12 12.0 0.0 2.3 3 0 0 3 3 3 0 TPR repeat TPR_14 PF13428.6 OQS02461.1 - 0.082 13.8 5.9 0.35 11.8 0.3 4.2 4 1 0 4 4 4 0 Tetratricopeptide repeat MatP PF06303.12 OQS02461.1 - 0.34 11.5 1.9 21 5.7 0.0 3.8 4 0 0 4 4 4 0 MatP N-terminal domain C2 PF00168.30 OQS02462.1 - 1.3e-09 38.2 0.0 2.9e-09 37.2 0.0 1.5 1 0 0 1 1 1 1 C2 domain Exo_endo_phos PF03372.23 OQS02462.1 - 6.4e-07 29.1 0.1 3.5e-06 26.7 0.0 2.0 2 0 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family UreF PF01730.16 OQS02464.1 - 2.5e-22 79.9 0.8 3.2e-22 79.6 0.8 1.1 1 0 0 1 1 1 1 UreF AMPK1_CBM PF16561.5 OQS02465.1 - 2.8e-34 117.2 0.3 4.8e-34 116.4 0.3 1.4 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase AMPKBI PF04739.15 OQS02465.1 - 1.3e-25 89.4 2.0 2.5e-25 88.5 2.0 1.4 1 0 0 1 1 1 1 5'-AMP-activated protein kinase beta subunit, interaction domain GSHPx PF00255.19 OQS02466.1 - 2.4e-39 133.3 0.5 3e-39 132.9 0.5 1.1 1 0 0 1 1 1 1 Glutathione peroxidase AhpC-TSA PF00578.21 OQS02466.1 - 1.4e-07 31.4 0.1 2e-07 31.0 0.1 1.3 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 OQS02466.1 - 0.012 15.4 0.0 0.017 14.9 0.0 1.3 1 0 0 1 1 1 0 Redoxin Ribosomal_S15 PF00312.22 OQS02467.1 - 4.2e-34 116.6 2.0 6e-34 116.1 2.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S15 Sec20 PF03908.13 OQS02467.1 - 0.024 14.5 0.2 0.064 13.2 0.2 1.7 1 1 0 1 1 1 0 Sec20 DUF3813 PF12758.7 OQS02467.1 - 0.035 14.4 0.5 0.41 11.0 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3813) Alpha_adaptinC2 PF02883.20 OQS02467.1 - 0.1 12.9 0.0 0.14 12.4 0.0 1.2 1 0 0 1 1 1 0 Adaptin C-terminal domain CTP_transf_1 PF01148.20 OQS02468.1 - 2.7e-37 129.0 13.3 4.4e-35 121.7 8.9 2.4 1 1 1 2 2 2 2 Cytidylyltransferase family Fijivirus_P9-2 PF06837.11 OQS02468.1 - 0.87 9.0 6.1 1.7 8.0 6.1 1.5 1 0 0 1 1 1 0 Fijivirus P9-2 protein CRCB PF02537.15 OQS02469.1 - 0.14 12.5 0.0 0.14 12.5 0.0 2.9 1 1 0 2 2 2 0 CrcB-like protein, Camphor Resistance (CrcB) Brix PF04427.18 OQS02470.1 - 4.6e-28 98.6 0.8 7.7e-28 97.9 0.8 1.3 1 0 0 1 1 1 1 Brix domain RRP14 PF15459.6 OQS02470.1 - 1.2 9.8 0.0 1.2 9.8 0.0 3.2 2 1 0 2 2 2 0 60S ribosome biogenesis protein Rrp14 Ssu72 PF04722.13 OQS02471.1 - 2.1e-58 197.0 0.0 4e-58 196.1 0.0 1.4 1 0 0 1 1 1 1 Ssu72-like protein CN_hydrolase PF00795.22 OQS02471.1 - 1.7e-37 129.1 0.0 3e-37 128.4 0.0 1.3 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase MORN PF02493.20 OQS02471.1 - 2e-26 90.2 44.4 8.5e-06 25.4 0.7 7.1 7 0 0 7 7 7 6 MORN repeat EF-hand_7 PF13499.6 OQS02471.1 - 0.031 14.7 0.1 0.074 13.5 0.1 1.6 1 0 0 1 1 1 0 EF-hand domain pair EF-hand_6 PF13405.6 OQS02471.1 - 0.13 12.2 0.0 0.37 10.8 0.0 1.8 1 0 0 1 1 1 0 EF-hand domain Ank_2 PF12796.7 OQS02473.1 - 1.8e-43 147.0 4.7 6.7e-15 55.4 0.3 4.6 2 1 2 4 4 4 4 Ankyrin repeats (3 copies) Pkinase PF00069.25 OQS02473.1 - 2.2e-40 138.7 0.0 3.8e-40 137.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQS02473.1 - 7.7e-39 133.5 0.0 1.2e-38 132.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Ank PF00023.30 OQS02473.1 - 5e-36 121.6 4.2 1.1e-05 25.6 0.0 7.7 7 0 0 7 7 7 6 Ankyrin repeat Ank_4 PF13637.6 OQS02473.1 - 2.2e-32 111.0 6.2 2.7e-09 37.4 0.0 6.9 2 2 5 7 7 7 6 Ankyrin repeats (many copies) Ank_5 PF13857.6 OQS02473.1 - 3.5e-31 106.8 6.7 8.8e-09 35.5 0.1 6.0 3 2 3 6 6 6 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQS02473.1 - 2.5e-24 82.7 2.3 0.02 15.4 0.0 8.8 8 0 0 8 8 8 5 Ankyrin repeat DZR PF12773.7 OQS02473.1 - 0.0032 17.4 3.2 0.0032 17.4 3.2 3.1 2 1 1 3 3 3 2 Double zinc ribbon Kinase-like PF14531.6 OQS02473.1 - 0.0036 16.7 0.0 0.0068 15.8 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 OQS02473.1 - 0.03 13.3 0.0 0.059 12.3 0.0 1.4 1 0 0 1 1 1 0 Haspin like kinase domain Kdo PF06293.14 OQS02473.1 - 0.079 12.3 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family zinc-ribbons_6 PF07191.12 OQS02473.1 - 0.32 11.0 13.1 4.5 7.3 0.4 3.4 3 0 0 3 3 3 0 zinc-ribbons zinc-ribbon_6 PF10005.9 OQS02473.1 - 0.38 11.5 10.1 3.2 8.5 2.2 3.0 2 1 1 3 3 3 0 zinc-ribbon domain DUF1856 PF08983.10 OQS02473.1 - 1.2 9.5 3.8 8 6.8 2.3 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1856) zf-RanBP PF00641.18 OQS02473.1 - 2.3 7.6 18.0 0.45 9.9 0.6 3.4 3 0 0 3 3 3 0 Zn-finger in Ran binding protein and others Myosin_head PF00063.21 OQS02474.1 - 2.6e-236 786.0 1.0 2.6e-236 786.0 1.0 1.4 2 0 0 2 2 2 1 Myosin head (motor domain) IQ PF00612.27 OQS02474.1 - 1.8e-14 52.1 73.3 0.0016 18.1 0.0 11.6 11 0 0 11 11 11 8 IQ calmodulin-binding motif Myosin_N PF02736.19 OQS02474.1 - 1.1e-06 28.4 0.2 2.1e-06 27.5 0.2 1.4 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain RNA_helicase PF00910.22 OQS02474.1 - 0.013 15.8 0.3 0.72 10.3 0.1 2.8 2 0 0 2 2 2 0 RNA helicase AAA_16 PF13191.6 OQS02474.1 - 0.029 14.7 1.2 0.11 12.9 0.0 2.6 3 0 0 3 3 3 0 AAA ATPase domain AAA_18 PF13238.6 OQS02474.1 - 0.084 13.4 0.1 0.3 11.6 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 OQS02474.1 - 0.1 12.8 0.1 0.58 10.4 0.1 2.3 1 0 0 1 1 1 0 AAA domain GHMP_kinases_N PF00288.26 OQS02475.1 - 2.5e-16 59.6 2.9 2.5e-16 59.6 2.9 2.3 2 0 0 2 2 2 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 OQS02475.1 - 0.0068 16.8 5.1 0.1 13.0 0.1 3.2 2 2 1 3 3 3 2 GHMP kinases C terminal DUF2863 PF11062.8 OQS02475.1 - 0.17 10.3 0.0 0.25 9.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2863) UCH PF00443.29 OQS02478.1 - 4.8e-41 140.9 0.0 7.6e-41 140.3 0.0 1.3 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 OQS02478.1 - 1.7e-09 37.7 0.6 0.012 15.2 0.0 3.0 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase zf-BED PF02892.15 OQS02479.1 - 0.0079 16.2 5.5 0.067 13.2 5.5 2.5 1 1 0 1 1 1 1 BED zinc finger Sex_peptide PF08138.11 OQS02479.1 - 0.043 14.0 0.5 0.1 12.7 0.5 1.6 1 0 0 1 1 1 0 Sex peptide (SP) family Peptidase_C1 PF00112.23 OQS02482.1 - 1.8e-64 217.9 7.4 2.8e-64 217.2 7.4 1.3 1 0 0 1 1 1 1 Papain family cysteine protease Asp PF00026.23 OQS02482.1 - 7.9e-55 186.5 0.4 1.2e-54 185.9 0.4 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease Inhibitor_I29 PF08246.12 OQS02482.1 - 1.4e-11 44.6 0.2 3.2e-11 43.5 0.2 1.6 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) TAXi_N PF14543.6 OQS02482.1 - 3.2e-09 37.3 0.1 1.7e-06 28.4 0.2 2.5 1 1 1 2 2 2 2 Xylanase inhibitor N-terminal TAXi_C PF14541.6 OQS02482.1 - 0.015 15.1 0.0 0.044 13.6 0.0 1.8 1 0 0 1 1 1 0 Xylanase inhibitor C-terminal Peptidase_C1_2 PF03051.15 OQS02482.1 - 0.081 11.7 2.0 4.9 5.8 0.1 2.2 2 0 0 2 2 2 0 Peptidase C1-like family DUF4023 PF13215.6 OQS02482.1 - 0.091 12.8 1.5 0.2 11.7 1.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4023) DnaJ PF00226.31 OQS02484.1 - 1.1e-23 83.1 1.4 1.9e-23 82.3 1.4 1.4 1 0 0 1 1 1 1 DnaJ domain Gemini_mov PF01708.16 OQS02486.1 - 0.18 11.6 0.8 0.32 10.8 0.8 1.4 1 0 0 1 1 1 0 Geminivirus putative movement protein TRAM_LAG1_CLN8 PF03798.16 OQS02487.1 - 2.3e-31 109.1 19.4 2.3e-31 109.1 19.4 1.8 2 0 0 2 2 2 1 TLC domain TMEM208_SND2 PF05620.11 OQS02487.1 - 0.079 12.7 2.6 1.6 8.5 0.1 2.7 2 0 0 2 2 2 0 SRP-independent targeting protein 2/TMEM208 HECT PF00632.25 OQS02489.1 - 1.5e-48 165.9 0.0 2.8e-48 165.0 0.0 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) PX PF00787.24 OQS02490.1 - 1.8e-11 44.0 0.1 4e-11 42.9 0.1 1.5 1 0 0 1 1 1 1 PX domain Pkinase PF00069.25 OQS02491.1 - 7.6e-66 222.2 0.0 8.9e-66 221.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQS02491.1 - 2.8e-29 102.2 0.0 3.8e-29 101.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 OQS02491.1 - 0.0016 17.4 0.1 0.0026 16.8 0.1 1.3 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 OQS02491.1 - 0.0055 16.1 0.1 0.0088 15.4 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OQS02491.1 - 0.063 13.2 0.1 0.33 10.8 0.1 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family TRAM_LAG1_CLN8 PF03798.16 OQS02492.1 - 1.1e-35 123.2 15.4 1.7e-35 122.6 15.4 1.3 1 0 0 1 1 1 1 TLC domain ECH_1 PF00378.20 OQS02494.1 - 6.1e-34 117.4 0.9 8.1e-34 117.0 0.9 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 OQS02494.1 - 2.8e-19 69.8 0.4 3.3e-19 69.6 0.4 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Bac_surface_Ag PF01103.23 OQS02496.1 - 8.1e-44 150.4 0.0 9.6e-44 150.2 0.0 1.1 1 0 0 1 1 1 1 Surface antigen POTRA PF07244.15 OQS02496.1 - 0.00021 21.8 0.0 0.00039 21.0 0.0 1.4 1 0 0 1 1 1 1 Surface antigen variable number repeat ShlB PF03865.13 OQS02496.1 - 0.012 15.1 0.0 0.91 8.9 0.0 2.2 2 0 0 2 2 2 0 Haemolysin secretion/activation protein ShlB/FhaC/HecB PDZ_6 PF17820.1 OQS02497.1 - 3e-10 39.8 0.0 0.011 15.6 0.1 4.9 5 0 0 5 5 5 2 PDZ domain PDZ PF00595.24 OQS02497.1 - 5.1e-06 26.8 0.0 0.032 14.6 0.0 4.3 4 0 0 4 4 4 1 PDZ domain zf-MYND PF01753.18 OQS02497.1 - 0.0046 17.0 12.5 0.0086 16.2 12.5 1.5 1 0 0 1 1 1 1 MYND finger PDZ_2 PF13180.6 OQS02497.1 - 0.028 14.8 0.1 0.18 12.1 0.0 2.3 2 0 0 2 2 2 0 PDZ domain zf-Mss51 PF13824.6 OQS02497.1 - 0.23 11.6 4.6 0.53 10.4 4.6 1.6 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 zf-RING_5 PF14634.6 OQS02498.1 - 4e-05 23.5 15.6 6.8e-05 22.7 15.6 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 OQS02498.1 - 0.0031 17.8 14.7 0.0062 16.8 14.7 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 OQS02498.1 - 0.0039 17.0 13.9 0.0069 16.2 13.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OQS02498.1 - 0.0046 16.9 5.8 0.0046 16.9 5.8 2.2 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 OQS02498.1 - 0.017 14.9 14.4 0.035 14.0 14.4 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) gp32 PF08804.10 OQS02498.1 - 0.026 14.6 0.5 0.036 14.1 0.5 1.2 1 0 0 1 1 1 0 gp32 DNA binding protein like zf-C3HC4 PF00097.25 OQS02498.1 - 0.31 11.0 13.9 0.65 9.9 13.9 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) SelK_SelG PF10961.8 OQS02498.1 - 0.48 11.1 1.9 2.3 8.9 1.9 2.0 1 1 0 1 1 1 0 Selenoprotein SelK_SelG zf-RING_6 PF14835.6 OQS02498.1 - 0.64 9.9 7.8 1.2 9.0 7.8 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein Prok-RING_4 PF14447.6 OQS02498.1 - 0.65 9.9 13.4 1.2 9.0 13.4 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 OQS02498.1 - 3.9 7.7 13.0 11 6.3 13.0 1.8 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING OB_NTP_bind PF07717.16 OQS02499.1 - 1.3e-21 76.7 0.1 3.4e-21 75.4 0.1 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.23 OQS02499.1 - 1.8e-20 73.2 0.0 1.8e-20 73.2 0.0 2.8 2 1 0 2 2 1 1 Helicase associated domain (HA2) Helicase_C PF00271.31 OQS02499.1 - 4e-13 49.7 0.0 1.3e-12 48.0 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 OQS02499.1 - 1.6e-07 31.3 0.2 5.4e-07 29.6 0.2 1.8 1 1 0 1 1 1 1 DEAD/DEAH box helicase T2SSE PF00437.20 OQS02499.1 - 7.5e-06 25.2 0.0 1.6e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_22 PF13401.6 OQS02499.1 - 0.0002 21.7 0.0 0.00091 19.5 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 OQS02499.1 - 0.00023 20.9 0.2 0.00065 19.5 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 OQS02499.1 - 0.0014 19.0 0.1 0.0032 17.8 0.1 1.6 1 0 0 1 1 1 1 AAA domain AAA_7 PF12775.7 OQS02499.1 - 0.0073 15.8 0.0 0.018 14.6 0.0 1.6 1 0 0 1 1 1 1 P-loop containing dynein motor region SRP54 PF00448.22 OQS02499.1 - 0.033 13.8 0.0 0.082 12.5 0.0 1.8 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_33 PF13671.6 OQS02499.1 - 0.037 14.2 0.0 0.12 12.5 0.0 2.0 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.27 OQS02499.1 - 1.9 9.0 0.0 1.9 9.0 0.0 2.9 2 1 0 2 2 1 0 ABC transporter AAA_22 PF13401.6 OQS02500.1 - 0.015 15.6 0.0 0.019 15.2 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 OQS02500.1 - 0.022 15.1 0.0 0.025 15.0 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain IstB_IS21 PF01695.17 OQS02500.1 - 0.036 13.8 0.0 0.047 13.4 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein NACHT PF05729.12 OQS02500.1 - 0.05 13.5 0.0 0.077 12.9 0.0 1.3 1 0 0 1 1 1 0 NACHT domain AAA_30 PF13604.6 OQS02500.1 - 0.099 12.4 0.0 0.12 12.1 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 OQS02500.1 - 0.11 12.4 0.0 0.22 11.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_23 PF13476.6 OQS02500.1 - 0.14 12.6 0.0 0.2 12.1 0.0 1.2 1 0 0 1 1 1 0 AAA domain DAP3 PF10236.9 OQS02500.1 - 0.2 10.8 0.0 0.4 9.8 0.0 1.4 1 1 1 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 Mog1 PF04603.12 OQS02501.1 - 1.4e-39 135.7 0.1 1.7e-39 135.4 0.1 1.1 1 0 0 1 1 1 1 Ran-interacting Mog1 protein EAV_GP5 PF15981.5 OQS02501.1 - 0.0049 17.3 0.9 0.05 14.0 0.1 2.5 2 1 1 3 3 3 1 Envelope glycoprotein GP 5 of equine arteritis virus SPACA9 PF15120.6 OQS02501.1 - 0.11 12.2 0.1 2.2 8.0 0.0 2.1 1 1 0 2 2 2 0 Sperm acrosome-associated protein 9 TIP49 PF06068.13 OQS02503.1 - 1.5e-170 567.1 0.5 4.5e-170 565.5 0.2 2.0 2 0 0 2 2 2 1 TIP49 P-loop domain DHC_N2 PF08393.13 OQS02503.1 - 5.7e-87 292.4 0.9 5.7e-87 292.4 0.9 2.7 3 0 0 3 3 1 1 Dynein heavy chain, N-terminal region 2 AAA_6 PF12774.7 OQS02503.1 - 5.9e-35 120.8 0.0 1.2e-34 119.7 0.0 1.6 1 0 0 1 1 1 1 Hydrolytic ATP binding site of dynein motor region Dynein_C PF18199.1 OQS02503.1 - 1.7e-21 76.8 0.7 4.8e-21 75.3 0.7 1.7 1 0 0 1 1 1 1 Dynein heavy chain C-terminal domain TIP49_C PF17856.1 OQS02503.1 - 1.5e-19 69.9 0.0 3.5e-19 68.7 0.0 1.7 1 0 0 1 1 1 1 TIP49 AAA-lid domain AAA_7 PF12775.7 OQS02503.1 - 2.9e-19 69.3 0.1 4.2e-14 52.5 0.0 5.1 4 1 0 4 4 4 1 P-loop containing dynein motor region AAA_9 PF12781.7 OQS02503.1 - 9.8e-18 64.1 0.1 3.3e-17 62.4 0.1 1.9 1 0 0 1 1 1 1 ATP-binding dynein motor region Dynein_AAA_lid PF17852.1 OQS02503.1 - 3.1e-15 56.4 0.5 1.6e-14 54.1 0.0 2.5 2 0 0 2 2 2 1 Dynein heavy chain AAA lid domain AAA_8 PF12780.7 OQS02503.1 - 1.7e-13 50.5 1.6 7.2e-13 48.5 0.0 2.7 3 0 0 3 3 3 1 P-loop containing dynein motor region D4 AAA PF00004.29 OQS02503.1 - 5.4e-13 49.5 2.7 0.00023 21.6 0.0 6.2 6 0 0 6 6 5 1 ATPase family associated with various cellular activities (AAA) Dynein_heavy PF03028.15 OQS02503.1 - 1e-11 45.0 0.2 5e-10 39.5 0.1 3.3 2 0 0 2 2 2 1 Dynein heavy chain region D6 P-loop domain AAA_22 PF13401.6 OQS02503.1 - 1.3e-10 41.7 2.1 0.17 12.2 0.0 7.0 6 0 0 6 6 6 1 AAA domain RuvB_N PF05496.12 OQS02503.1 - 8.1e-10 38.7 0.6 0.00014 21.6 0.0 4.3 4 0 0 4 4 4 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 OQS02503.1 - 9.8e-08 32.6 13.6 0.38 11.1 0.1 7.3 6 2 0 6 6 5 2 AAA ATPase domain AAA_29 PF13555.6 OQS02503.1 - 1.8e-06 27.6 2.4 0.19 11.5 0.0 4.8 4 0 0 4 4 4 2 P-loop containing region of AAA domain AAA_lid_1 PF17857.1 OQS02503.1 - 9.6e-06 25.8 0.0 2.9e-05 24.2 0.0 1.9 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 OQS02503.1 - 4.7e-05 23.4 1.1 1.3 9.0 0.0 5.1 4 0 0 4 4 4 1 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 OQS02503.1 - 0.00013 22.2 0.0 2.7 8.1 0.0 4.3 4 0 0 4 4 3 1 AAA domain AAA_18 PF13238.6 OQS02503.1 - 0.00021 21.9 1.5 3 8.4 0.0 5.1 6 0 0 6 6 4 1 AAA domain AAA_28 PF13521.6 OQS02503.1 - 0.00031 21.0 0.4 0.38 11.0 0.0 4.3 3 0 0 3 3 3 1 AAA domain FtsK_SpoIIIE PF01580.18 OQS02503.1 - 0.0022 17.4 0.7 15 4.9 0.0 4.7 4 0 0 4 4 4 0 FtsK/SpoIIIE family MMR_HSR1 PF01926.23 OQS02503.1 - 0.0025 17.9 3.6 0.23 11.5 0.0 5.1 5 0 0 5 5 5 1 50S ribosome-binding GTPase RNA_helicase PF00910.22 OQS02503.1 - 0.0039 17.6 0.1 1.5e+02 2.8 0.0 5.4 5 0 0 5 5 5 0 RNA helicase NACHT PF05729.12 OQS02503.1 - 0.0099 15.8 1.3 4.1 7.3 0.0 4.2 3 0 0 3 3 3 1 NACHT domain Mg_chelatase PF01078.21 OQS02503.1 - 0.012 15.0 3.4 1.3 8.3 0.1 4.1 4 0 0 4 4 4 0 Magnesium chelatase, subunit ChlI DnaB_C PF03796.15 OQS02503.1 - 0.013 14.8 1.7 1.1 8.5 0.0 3.5 3 0 0 3 3 3 0 DnaB-like helicase C terminal domain Sigma54_activat PF00158.26 OQS02503.1 - 0.028 14.1 0.2 77 2.9 0.0 4.1 4 0 0 4 4 4 0 Sigma-54 interaction domain AIG1 PF04548.16 OQS02503.1 - 0.046 13.0 0.1 0.16 11.2 0.0 2.0 2 0 0 2 2 2 0 AIG1 family NB-ARC PF00931.22 OQS02503.1 - 0.066 12.4 0.7 31 3.6 0.0 4.0 4 0 0 4 4 4 0 NB-ARC domain Roc PF08477.13 OQS02503.1 - 0.073 13.3 0.0 8.1 6.7 0.0 3.4 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase MT PF12777.7 OQS02503.1 - 0.11 11.5 0.7 0.32 10.0 0.5 1.7 1 1 0 1 1 1 0 Microtubule-binding stalk of dynein motor AAA_17 PF13207.6 OQS02503.1 - 0.16 12.4 1.2 6.6 7.2 0.1 3.1 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 OQS02503.1 - 0.2 10.9 1.4 1.9 7.7 0.3 2.8 2 0 0 2 2 2 0 Zeta toxin TsaE PF02367.17 OQS02503.1 - 0.23 11.5 3.3 4.5 7.3 0.0 4.1 4 0 0 4 4 4 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_25 PF13481.6 OQS02503.1 - 0.27 10.8 6.1 0.26 10.8 0.1 3.5 4 0 0 4 4 3 0 AAA domain PduV-EutP PF10662.9 OQS02503.1 - 0.28 10.9 2.7 31 4.3 0.0 4.7 6 0 0 6 6 5 0 Ethanolamine utilisation - propanediol utilisation AAA_19 PF13245.6 OQS02503.1 - 0.32 11.3 7.5 7.2 6.9 1.6 5.0 4 1 0 4 4 3 0 AAA domain Viral_helicase1 PF01443.18 OQS02503.1 - 0.33 10.6 2.8 0.42 10.3 0.2 2.6 3 0 0 3 3 3 0 Viral (Superfamily 1) RNA helicase ATPase PF06745.13 OQS02503.1 - 0.58 9.5 2.9 13 5.1 0.1 3.9 4 0 0 4 4 4 0 KaiC RsgA_GTPase PF03193.16 OQS02503.1 - 0.73 9.7 4.1 6.4 6.6 0.0 4.3 4 0 0 4 4 4 0 RsgA GTPase ABC_tran PF00005.27 OQS02503.1 - 5.5 7.5 17.7 14 6.1 1.2 6.3 7 0 0 7 7 5 0 ABC transporter Atg8 PF02991.16 OQS02504.1 - 1.2e-51 173.2 0.1 1.4e-51 173.0 0.1 1.0 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.13 OQS02504.1 - 2.5e-07 31.0 0.0 3.1e-07 30.7 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Ank_2 PF12796.7 OQS02505.1 - 2.1e-20 73.1 14.8 7.5e-07 29.7 0.1 4.0 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OQS02505.1 - 2.3e-16 59.6 6.9 0.0051 17.1 0.0 7.0 2 1 5 7 7 7 6 Ankyrin repeats (many copies) Ank_4 PF13637.6 OQS02505.1 - 1.3e-14 54.4 12.1 0.00022 21.7 0.1 6.4 3 2 2 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQS02505.1 - 2.7e-12 45.7 6.8 2.3 9.1 0.1 8.4 8 1 1 9 9 9 4 Ankyrin repeat DUF5049 PF16468.5 OQS02505.1 - 0.00023 21.0 1.9 23 4.9 0.0 5.7 2 1 4 6 6 6 1 Domain of unknown function (DUF5049) Ank PF00023.30 OQS02505.1 - 0.011 16.1 3.9 13 6.4 0.1 5.5 2 2 1 3 3 3 0 Ankyrin repeat ABC_membrane PF00664.23 OQS02506.1 - 2e-56 191.7 34.2 3e-30 105.8 15.4 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 OQS02506.1 - 6e-46 156.4 0.0 5e-26 91.8 0.0 2.9 3 0 0 3 3 3 2 ABC transporter SMC_N PF02463.19 OQS02506.1 - 3.9e-05 23.2 3.8 0.0039 16.7 2.5 3.0 2 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 OQS02506.1 - 0.0011 18.9 0.1 1.3 8.9 0.0 2.8 3 0 0 3 3 3 2 RsgA GTPase MMR_HSR1 PF01926.23 OQS02506.1 - 0.0056 16.7 1.3 0.31 11.1 0.1 2.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_16 PF13191.6 OQS02506.1 - 0.0065 16.9 0.0 2.8 8.3 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain RNA_helicase PF00910.22 OQS02506.1 - 0.23 11.9 0.5 26 5.3 0.0 3.1 3 0 0 3 3 3 0 RNA helicase SNF2_N PF00176.23 OQS02507.1 - 1.1e-60 205.2 1.2 2.4e-60 204.1 1.2 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain PHD PF00628.29 OQS02507.1 - 7.7e-24 83.3 43.3 1.7e-11 43.8 5.5 4.7 4 0 0 4 4 4 4 PHD-finger Helicase_C PF00271.31 OQS02507.1 - 1.8e-20 73.3 0.1 6.4e-20 71.6 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Bromodomain PF00439.25 OQS02507.1 - 3.2e-17 62.4 0.0 1.2e-16 60.5 0.0 2.1 1 0 0 1 1 1 1 Bromodomain Chromo PF00385.24 OQS02507.1 - 1e-12 47.8 0.1 5.7e-06 26.1 0.0 3.7 4 0 0 4 4 4 2 Chromo (CHRromatin Organisation MOdifier) domain ResIII PF04851.15 OQS02507.1 - 8.9e-09 35.6 1.7 1.9e-08 34.5 0.0 2.5 3 0 0 3 3 2 1 Type III restriction enzyme, res subunit PHD_2 PF13831.6 OQS02507.1 - 1.2e-08 34.3 13.4 0.00028 20.4 1.2 3.9 3 0 0 3 3 3 3 PHD-finger HDA2-3 PF11496.8 OQS02507.1 - 9.6e-07 28.2 0.1 4.1e-06 26.2 0.1 2.1 2 0 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 PDZ PF00595.24 OQS02507.1 - 1.6e-05 25.2 0.0 5e-05 23.6 0.0 1.9 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 OQS02507.1 - 0.0006 19.6 0.0 0.0015 18.3 0.0 1.6 1 0 0 1 1 1 1 PDZ domain DEAD PF00270.29 OQS02507.1 - 0.0018 18.1 0.0 0.0086 15.9 0.0 2.1 1 1 0 1 1 1 1 DEAD/DEAH box helicase Rubredoxin PF00301.20 OQS02507.1 - 0.96 9.5 7.9 8.9 6.4 0.5 3.0 2 0 0 2 2 2 0 Rubredoxin zf-RING_2 PF13639.6 OQS02507.1 - 2.4 8.6 51.5 0.57 10.6 6.1 5.4 5 0 0 5 5 5 0 Ring finger domain TPR_19 PF14559.6 OQS02508.1 - 1.3e-34 118.5 25.0 1e-05 25.9 0.3 11.1 8 2 4 12 12 12 8 Tetratricopeptide repeat TPR_1 PF00515.28 OQS02508.1 - 7.6e-28 95.2 33.1 0.00017 21.3 0.0 14.5 16 0 0 16 16 16 6 Tetratricopeptide repeat TPR_2 PF07719.17 OQS02508.1 - 1.2e-26 90.6 37.3 0.0039 17.2 0.0 16.2 18 0 0 18 18 17 7 Tetratricopeptide repeat TPR_12 PF13424.6 OQS02508.1 - 5.7e-26 90.6 24.9 0.00039 20.7 0.0 11.6 8 3 2 10 10 10 5 Tetratricopeptide repeat TPR_16 PF13432.6 OQS02508.1 - 4.9e-25 87.9 28.0 4e-05 24.2 0.1 10.1 12 0 0 12 12 10 4 Tetratricopeptide repeat TPR_14 PF13428.6 OQS02508.1 - 1.5e-20 72.1 28.2 0.066 14.1 0.2 12.5 10 3 4 14 14 12 7 Tetratricopeptide repeat TPR_8 PF13181.6 OQS02508.1 - 3.7e-20 70.4 31.7 0.0051 16.9 0.0 14.1 17 0 0 17 17 15 4 Tetratricopeptide repeat TPR_7 PF13176.6 OQS02508.1 - 3.2e-19 67.5 22.5 0.00085 19.2 0.0 11.6 12 0 0 12 12 11 4 Tetratricopeptide repeat TPR_6 PF13174.6 OQS02508.1 - 1.7e-13 50.3 31.6 0.049 14.3 0.0 13.2 15 1 0 15 15 12 4 Tetratricopeptide repeat ANAPC3 PF12895.7 OQS02508.1 - 1e-12 48.1 26.8 3.2e-05 24.1 1.9 7.4 5 2 2 7 7 7 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.6 OQS02508.1 - 1.1e-11 44.3 17.3 0.11 12.9 0.1 11.2 12 1 0 12 12 11 3 Tetratricopeptide repeat TPR_10 PF13374.6 OQS02508.1 - 8.4e-09 35.0 14.0 1.3 9.0 0.1 9.1 10 0 0 10 10 8 2 Tetratricopeptide repeat TPR_11 PF13414.6 OQS02508.1 - 2.1e-08 33.7 20.3 0.09 12.5 0.1 10.0 9 1 2 11 11 11 3 TPR repeat TPR_9 PF13371.6 OQS02508.1 - 2.2e-06 27.7 10.7 0.28 11.4 0.3 6.7 6 2 2 8 8 8 3 Tetratricopeptide repeat TPR_20 PF14561.6 OQS02508.1 - 1.9e-05 24.9 17.4 0.2 12.0 0.1 7.9 6 2 3 9 9 9 1 Tetratricopeptide repeat HrpB1_HrpK PF09613.10 OQS02508.1 - 8e-05 22.3 4.9 0.27 10.9 0.5 4.6 4 0 0 4 4 4 1 Bacterial type III secretion protein (HrpB1_HrpK) MIT PF04212.18 OQS02508.1 - 0.00015 21.8 10.1 0.36 10.9 0.3 5.8 5 0 0 5 5 5 2 MIT (microtubule interacting and transport) domain YfiO PF13525.6 OQS02508.1 - 0.0045 16.7 0.3 0.0045 16.7 0.3 3.9 3 1 0 3 3 3 1 Outer membrane lipoprotein DUF4810 PF16068.5 OQS02508.1 - 0.012 16.1 0.7 37 5.0 0.0 4.9 4 1 1 5 5 5 0 Domain of unknown function (DUF4810) TPR_5 PF12688.7 OQS02508.1 - 0.11 12.7 2.6 20 5.4 0.0 4.6 4 1 1 5 5 4 0 Tetratrico peptide repeat FYVE PF01363.21 OQS02509.1 - 7.7e-21 74.0 53.9 1.9e-10 40.7 11.8 3.3 1 1 2 3 3 3 3 FYVE zinc finger FYVE_2 PF02318.16 OQS02509.1 - 2e-06 28.0 47.3 0.003 17.8 15.5 3.4 2 1 1 3 3 3 3 FYVE-type zinc finger ANF_receptor PF01094.28 OQS02510.1 - 3.3e-13 49.5 0.7 6.1e-13 48.6 0.4 1.7 2 0 0 2 2 2 1 Receptor family ligand binding region SPC12 PF06645.13 OQS02510.1 - 0.32 11.1 4.2 0.13 12.4 0.4 2.4 2 0 0 2 2 2 0 Microsomal signal peptidase 12 kDa subunit (SPC12) Glyco_hydro_18 PF00704.28 OQS02511.1 - 6.8e-22 78.6 1.0 1.2e-21 77.7 0.2 1.8 2 1 0 2 2 2 1 Glycosyl hydrolases family 18 GHL10 PF02638.15 OQS02511.1 - 0.026 13.6 0.1 0.085 11.9 0.0 1.7 1 1 0 2 2 2 0 Glycosyl hydrolase-like 10 Trypsin_2 PF13365.6 OQS02514.1 - 4.7e-25 89.2 5.2 1.6e-19 71.3 0.2 3.2 3 0 0 3 3 3 2 Trypsin-like peptidase domain PDZ_1 PF12812.7 OQS02514.1 - 2e-23 82.2 0.0 4e-16 58.8 0.0 2.6 2 0 0 2 2 2 2 PDZ-like domain PDZ_2 PF13180.6 OQS02514.1 - 3.5e-16 59.3 1.3 6.2e-07 29.7 0.0 4.5 4 0 0 4 4 4 3 PDZ domain PDZ_6 PF17820.1 OQS02514.1 - 1.2e-15 57.1 0.7 6.7e-05 22.7 0.0 5.7 6 0 0 6 6 6 4 PDZ domain PDZ PF00595.24 OQS02514.1 - 1e-09 38.6 0.0 0.00013 22.2 0.0 4.0 4 0 0 4 4 4 2 PDZ domain Peptidase_S46 PF10459.9 OQS02514.1 - 0.0025 16.6 0.3 0.0064 15.2 0.1 1.6 2 0 0 2 2 2 1 Peptidase S46 Trypsin PF00089.26 OQS02514.1 - 0.01 15.6 0.0 0.03 14.1 0.0 1.7 1 0 0 1 1 1 0 Trypsin Tricorn_PDZ PF14685.6 OQS02514.1 - 0.018 15.0 3.2 0.79 9.7 0.1 3.9 5 0 0 5 5 5 0 Tricorn protease PDZ domain PDZ_3 PF17815.1 OQS02514.1 - 0.041 13.8 0.0 8 6.3 0.0 3.1 3 0 0 3 3 3 0 PDZ domain Peptidase_S7 PF00949.21 OQS02514.1 - 0.085 12.7 0.7 0.2 11.5 0.7 1.6 1 0 0 1 1 1 0 Peptidase S7, Flavivirus NS3 serine protease WD40 PF00400.32 OQS02515.1 - 9.9e-21 73.7 47.2 7.8e-05 23.4 0.7 12.2 12 0 0 12 12 12 9 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OQS02515.1 - 6.8e-09 35.9 10.8 0.27 11.5 0.1 8.3 5 3 2 7 7 7 4 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 OQS02515.1 - 0.0021 17.4 3.6 0.38 10.0 0.3 4.0 4 1 0 4 4 4 1 WD40-like domain Kelch_6 PF13964.6 OQS02515.1 - 0.016 15.5 1.2 0.37 11.1 0.0 3.9 5 0 0 5 5 5 0 Kelch motif FAIM1 PF06905.13 OQS02516.1 - 8e-08 32.2 0.0 1.2e-07 31.7 0.0 1.2 1 0 0 1 1 1 1 Fas apoptotic inhibitory molecule (FAIM1) zf-RanBP PF00641.18 OQS02516.1 - 3.5e-06 26.2 1.9 3.5e-06 26.2 1.9 2.0 2 0 0 2 2 2 1 Zn-finger in Ran binding protein and others CBM_35 PF16990.5 OQS02516.1 - 0.059 13.6 0.0 0.11 12.8 0.0 1.4 1 0 0 1 1 1 0 Carbohydrate binding module (family 35) Vps36-NZF-N PF16988.5 OQS02516.1 - 0.29 10.6 3.9 1.1 8.6 3.9 2.0 1 1 0 1 1 1 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain PX PF00787.24 OQS02517.1 - 1.1e-08 35.0 0.0 2.3e-08 34.0 0.0 1.4 1 0 0 1 1 1 1 PX domain Sec8_exocyst PF04048.14 OQS02518.1 - 1.6e-11 44.3 0.3 6.8e-11 42.2 0.3 2.1 1 0 0 1 1 1 1 Sec8 exocyst complex component specific domain COG2 PF06148.11 OQS02518.1 - 0.24 11.5 2.2 0.65 10.1 0.1 2.8 3 0 0 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 PAN_1 PF00024.26 OQS02519.1 - 5.5e-10 39.1 16.8 8.6e-08 32.0 0.8 3.3 3 0 0 3 3 3 2 PAN domain PAN_4 PF14295.6 OQS02519.1 - 1.4e-07 31.3 11.4 2.4e-06 27.4 1.9 4.2 5 0 0 5 5 5 2 PAN domain PAN_3 PF08277.12 OQS02519.1 - 0.0049 16.6 3.4 0.0049 16.6 3.4 3.1 3 0 0 3 3 3 1 PAN-like domain PAN_2 PF08276.11 OQS02519.1 - 0.012 15.7 13.8 0.12 12.5 3.9 3.2 2 1 0 2 2 2 0 PAN-like domain Dickkopf_N PF04706.12 OQS02519.1 - 0.043 14.3 1.4 0.043 14.3 1.4 3.4 3 0 0 3 3 3 0 Dickkopf N-terminal cysteine-rich region PAN_1 PF00024.26 OQS02520.1 - 3e-10 39.9 12.5 2.4e-07 30.6 2.8 3.4 2 1 1 3 3 3 2 PAN domain PAN_4 PF14295.6 OQS02520.1 - 6.9e-10 38.7 32.9 8.1e-07 28.9 0.6 4.4 4 1 0 4 4 4 3 PAN domain Dickkopf_N PF04706.12 OQS02520.1 - 0.023 15.2 1.0 0.023 15.2 1.0 3.2 3 0 0 3 3 3 0 Dickkopf N-terminal cysteine-rich region Ntox44 PF15607.6 OQS02520.1 - 0.043 14.1 1.7 0.33 11.3 0.0 2.3 2 0 0 2 2 2 0 Bacterial toxin 44 PAN_2 PF08276.11 OQS02520.1 - 0.42 10.7 15.7 0.13 12.4 2.5 2.9 3 0 0 3 3 3 0 PAN-like domain PAN_3 PF08277.12 OQS02520.1 - 0.54 10.1 13.9 0.074 12.9 2.1 3.1 3 0 0 3 3 3 0 PAN-like domain ABC_membrane PF00664.23 OQS02521.1 - 1.6e-97 326.5 30.0 4.2e-54 184.1 7.7 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 OQS02521.1 - 2.5e-70 235.3 0.0 6.5e-34 117.4 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 OQS02521.1 - 6.4e-12 45.4 0.2 4.5e-05 23.0 0.0 3.8 2 2 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 OQS02521.1 - 3.9e-06 26.8 0.4 0.085 12.5 0.0 2.4 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.6 OQS02521.1 - 1e-05 25.2 2.8 0.034 13.9 0.3 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 OQS02521.1 - 1e-05 26.0 2.2 0.036 14.4 0.1 2.8 2 1 0 2 2 2 2 AAA ATPase domain G-alpha PF00503.20 OQS02521.1 - 1.1e-05 24.8 0.0 0.095 11.8 0.0 2.3 2 0 0 2 2 2 2 G-protein alpha subunit RsgA_GTPase PF03193.16 OQS02521.1 - 1.2e-05 25.2 0.1 0.12 12.2 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA PF00004.29 OQS02521.1 - 2.8e-05 24.6 0.9 0.57 10.6 0.0 4.1 2 2 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.12 OQS02521.1 - 5.8e-05 22.5 0.1 0.25 10.6 0.0 2.3 2 0 0 2 2 2 2 Zeta toxin ABC_ATPase PF09818.9 OQS02521.1 - 9.3e-05 21.4 1.1 0.27 10.0 0.1 2.7 3 0 0 3 3 3 2 Predicted ATPase of the ABC class DUF87 PF01935.17 OQS02521.1 - 0.00018 21.7 0.2 0.53 10.3 0.0 2.5 2 0 0 2 2 2 2 Helicase HerA, central domain AAA_22 PF13401.6 OQS02521.1 - 0.00045 20.5 2.2 0.84 9.9 0.1 3.6 2 2 0 2 2 2 2 AAA domain AAA_24 PF13479.6 OQS02521.1 - 0.00072 19.3 0.0 0.36 10.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.6 OQS02521.1 - 0.0018 18.2 3.2 1.9 8.2 0.1 3.6 3 1 0 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_25 PF13481.6 OQS02521.1 - 0.0018 17.8 1.5 1.2 8.7 0.0 3.4 3 0 0 3 3 3 1 AAA domain AAA_5 PF07728.14 OQS02521.1 - 0.0042 17.1 0.1 5.7 6.9 0.0 3.4 4 0 0 4 4 3 0 AAA domain (dynein-related subfamily) AAA_7 PF12775.7 OQS02521.1 - 0.0042 16.6 0.0 2.9 7.3 0.0 2.4 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_30 PF13604.6 OQS02521.1 - 0.0072 16.1 0.1 3.4 7.4 0.0 2.9 2 2 0 2 2 2 1 AAA domain SbcCD_C PF13558.6 OQS02521.1 - 0.011 15.9 3.9 6.2 7.1 0.3 3.9 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_28 PF13521.6 OQS02521.1 - 0.013 15.8 0.3 2.8 8.2 0.0 2.5 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 OQS02521.1 - 0.015 15.4 0.1 6.1 7.0 0.0 2.9 2 0 0 2 2 2 0 50S ribosome-binding GTPase PRK PF00485.18 OQS02521.1 - 0.017 14.8 0.2 4.5 7.0 0.0 2.4 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family AAA_18 PF13238.6 OQS02521.1 - 0.019 15.5 0.1 3 8.4 0.1 2.6 2 0 0 2 2 2 0 AAA domain APS_kinase PF01583.20 OQS02521.1 - 0.021 14.7 0.2 3.5 7.5 0.0 2.4 2 0 0 2 2 2 0 Adenylylsulphate kinase AAA_33 PF13671.6 OQS02521.1 - 0.031 14.4 0.2 5.8 7.1 0.0 2.6 2 0 0 2 2 2 0 AAA domain Rad17 PF03215.15 OQS02521.1 - 0.04 13.8 0.3 0.89 9.4 0.0 2.6 3 0 0 3 3 2 0 Rad17 P-loop domain ATP-synt_ab PF00006.25 OQS02521.1 - 0.061 13.0 0.0 7.3 6.2 0.0 2.4 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain Roc PF08477.13 OQS02521.1 - 0.072 13.3 0.1 6 7.1 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase RNA_helicase PF00910.22 OQS02521.1 - 0.077 13.4 0.1 17 5.9 0.0 2.7 2 0 0 2 2 2 0 RNA helicase 6PF2K PF01591.18 OQS02521.1 - 0.12 11.7 0.0 0.29 10.4 0.0 1.5 1 0 0 1 1 1 0 6-phosphofructo-2-kinase Saf_2TM PF18303.1 OQS02521.1 - 0.19 11.3 1.9 10 5.7 0.1 2.8 2 0 0 2 2 2 0 SAVED-fused 2TM effector domain WD40 PF00400.32 OQS02522.1 - 1.3e-06 29.0 5.2 0.0094 16.8 0.1 5.3 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OQS02522.1 - 0.00023 21.4 0.3 0.46 10.8 0.0 3.8 3 0 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain ThiF PF00899.21 OQS02523.1 - 4.7e-30 104.7 0.0 5.8e-30 104.4 0.0 1.0 1 0 0 1 1 1 1 ThiF family 2-Hacid_dh_C PF02826.19 OQS02523.1 - 0.0098 15.3 0.0 0.02 14.3 0.0 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_7 PF13241.6 OQS02523.1 - 0.018 15.5 0.0 0.042 14.3 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding CHCH PF06747.13 OQS02524.1 - 0.014 15.5 1.2 0.014 15.5 1.2 3.3 2 1 0 3 3 3 0 CHCH domain CX9C PF16860.5 OQS02524.1 - 0.052 13.6 6.2 0.11 12.6 1.0 2.4 2 1 0 2 2 2 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, Pet191_N PF10203.9 OQS02524.1 - 0.2 12.0 7.2 2.5 8.4 0.2 3.0 1 1 1 2 2 2 0 Cytochrome c oxidase assembly protein PET191 Cmc1 PF08583.10 OQS02524.1 - 3.8 7.6 11.1 1.3 9.1 1.7 2.5 1 1 1 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like NAC PF01849.18 OQS02525.1 - 1.6e-19 69.6 0.0 2.4e-19 69.0 0.0 1.3 1 0 0 1 1 1 1 NAC domain DUF4611 PF15387.6 OQS02525.1 - 0.056 13.7 0.1 0.099 12.9 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) Pkinase_Tyr PF07714.17 OQS02526.1 - 1.4e-78 263.8 7.2 3e-32 111.9 0.2 4.4 4 1 0 4 4 4 3 Protein tyrosine kinase Pkinase PF00069.25 OQS02526.1 - 3.2e-74 249.6 6.9 1.2e-36 126.5 0.6 4.3 3 1 0 3 3 3 3 Protein kinase domain Kdo PF06293.14 OQS02526.1 - 0.015 14.7 3.2 1.2 8.5 0.3 2.9 3 0 0 3 3 3 0 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 OQS02526.1 - 0.038 13.6 0.0 13 5.3 0.0 2.7 2 1 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 RIO1 PF01163.22 OQS02526.1 - 0.84 9.2 8.4 0.13 11.9 0.9 2.8 2 1 1 3 3 3 0 RIO1 family NatB_MDM20 PF09797.9 OQS02527.1 - 7.9e-70 235.7 4.3 7.9e-70 235.7 4.3 1.7 2 0 0 2 2 2 1 N-acetyltransferase B complex (NatB) non catalytic subunit CHGN PF05679.16 OQS02527.1 - 0.049 12.4 0.0 0.082 11.7 0.0 1.3 1 0 0 1 1 1 0 Chondroitin N-acetylgalactosaminyltransferase Ras PF00071.22 OQS02528.1 - 1.2e-34 119.2 0.0 2.1e-34 118.5 0.0 1.4 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OQS02528.1 - 3.3e-27 95.1 0.0 7.3e-27 94.0 0.0 1.6 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OQS02528.1 - 6e-14 51.9 0.1 9.7e-14 51.2 0.1 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family GATase_4 PF13230.6 OQS02528.1 - 5.6e-12 45.1 0.0 2.2e-09 36.7 0.0 2.6 2 1 0 2 2 2 2 Glutamine amidotransferases class-II GATase_6 PF13522.6 OQS02528.1 - 3e-10 40.4 0.0 6.1e-10 39.4 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain Gtr1_RagA PF04670.12 OQS02528.1 - 4e-06 26.4 0.0 6.3e-06 25.7 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 OQS02528.1 - 4.9e-05 23.4 0.0 0.00011 22.2 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 OQS02528.1 - 0.00013 21.5 0.3 0.002 17.7 0.3 2.3 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 OQS02528.1 - 0.00053 19.9 0.1 0.0022 17.9 0.0 1.9 2 0 0 2 2 2 1 RsgA GTPase SRPRB PF09439.10 OQS02528.1 - 0.0011 18.4 0.0 0.0021 17.5 0.0 1.4 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 OQS02528.1 - 0.0028 16.9 0.0 0.021 14.0 0.0 2.2 2 1 1 3 3 3 1 G-protein alpha subunit PduV-EutP PF10662.9 OQS02528.1 - 0.0062 16.3 0.1 0.11 12.3 0.1 2.4 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation ATP_bind_1 PF03029.17 OQS02528.1 - 0.032 14.0 0.7 2.1 8.1 0.1 2.4 1 1 0 2 2 2 0 Conserved hypothetical ATP binding protein Ribosomal_L13 PF00572.18 OQS02529.1 - 2.6e-52 176.3 0.0 3.1e-52 176.0 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L13 DUF2807 PF10988.8 OQS02530.1 - 4.1e-11 43.0 4.9 7.7e-11 42.1 4.9 1.5 1 0 0 1 1 1 1 Putative auto-transporter adhesin, head GIN domain Methyltransf_3 PF01596.17 OQS02531.1 - 3.3e-38 131.0 0.0 5e-38 130.4 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase UPF0176_N PF17773.1 OQS02531.1 - 4.1e-20 71.9 0.0 9.9e-20 70.7 0.0 1.7 1 0 0 1 1 1 1 UPF0176 acylphosphatase like domain Rhodanese_C PF12368.8 OQS02531.1 - 5.1e-17 62.0 10.1 1.1e-16 60.9 10.1 1.6 1 0 0 1 1 1 1 Rhodanase C-terminal Methyltransf_24 PF13578.6 OQS02531.1 - 3.2e-13 50.6 0.0 1e-12 49.0 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Rhodanese PF00581.20 OQS02531.1 - 1.3e-09 38.5 0.4 6.6e-09 36.2 0.0 2.4 3 1 0 3 3 2 1 Rhodanese-like domain Methyltransf_31 PF13847.6 OQS02531.1 - 6.5e-09 35.7 0.0 1.6e-08 34.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OQS02531.1 - 1.2e-08 35.6 0.0 3.2e-08 34.1 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 OQS02531.1 - 5e-07 29.4 0.0 8.5e-07 28.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.12 OQS02531.1 - 3e-06 27.9 0.0 7.7e-06 26.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 OQS02531.1 - 7.2e-06 25.6 0.0 1.3e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_11 PF08241.12 OQS02531.1 - 2e-05 25.2 0.0 4.7e-05 24.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.15 OQS02531.1 - 3.5e-05 23.5 0.0 6.1e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 Conserved hypothetical protein 95 PCMT PF01135.19 OQS02531.1 - 0.00061 19.6 0.0 0.0011 18.8 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Ubie_methyltran PF01209.18 OQS02531.1 - 0.00079 18.8 0.0 0.0013 18.1 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_9 PF08003.11 OQS02531.1 - 0.0029 16.6 0.0 0.0051 15.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) DUF938 PF06080.12 OQS02531.1 - 0.0056 16.5 0.0 0.011 15.5 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF938) Methyltransf_18 PF12847.7 OQS02531.1 - 0.0092 15.9 0.0 0.02 14.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OQS02531.1 - 0.016 15.1 0.0 0.032 14.1 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain CHB_HEX PF03173.13 OQS02531.1 - 0.023 14.4 0.0 0.72 9.5 0.0 2.5 2 0 0 2 2 2 0 Putative carbohydrate binding domain PrmA PF06325.13 OQS02531.1 - 0.038 13.4 0.1 0.098 12.0 0.0 1.6 1 1 1 2 2 2 0 Ribosomal protein L11 methyltransferase (PrmA) Spermine_synth PF01564.17 OQS02531.1 - 0.063 12.7 0.0 0.12 11.8 0.0 1.4 1 0 0 1 1 1 0 Spermine/spermidine synthase domain DUF3228 PF11539.8 OQS02532.1 - 2.7e-73 245.6 0.0 3.2e-73 245.4 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3228) Myb_DNA-binding PF00249.31 OQS02533.1 - 1.6e-21 76.2 6.5 1.2e-13 51.0 3.0 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OQS02533.1 - 6.4e-11 42.3 4.0 3.4e-05 24.0 0.8 2.6 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OQS02533.1 - 8e-08 32.1 0.8 0.017 15.0 0.0 2.6 2 0 0 2 2 2 2 Myb DNA-binding like DUF1086 PF06461.11 OQS02533.1 - 0.00055 19.8 0.3 0.021 14.7 0.0 2.6 2 0 0 2 2 2 1 Domain of Unknown Function (DUF1086) Mu-like_gpT PF10124.9 OQS02533.1 - 0.1 11.9 2.1 0.41 9.9 0.1 2.5 3 0 0 3 3 3 0 Mu-like prophage major head subunit gpT DUF1279 PF06916.13 OQS02534.1 - 0.11 13.1 1.5 0.52 10.9 0.6 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF1279) RICTOR_M PF14666.6 OQS02534.1 - 0.15 11.8 0.0 0.31 10.8 0.0 1.4 1 0 0 1 1 1 0 Rapamycin-insensitive companion of mTOR, middle domain La PF05383.17 OQS02535.1 - 7.7e-19 67.5 0.2 1.4e-18 66.7 0.2 1.5 1 0 0 1 1 1 1 La domain RRM_1 PF00076.22 OQS02535.1 - 0.00026 20.8 0.0 0.001 18.8 0.0 2.1 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SRP-alpha_N PF04086.13 OQS02535.1 - 0.42 10.5 20.6 0.37 10.7 8.3 2.1 2 0 0 2 2 2 0 Signal recognition particle, alpha subunit, N-terminal RR_TM4-6 PF06459.12 OQS02535.1 - 0.9 9.3 12.0 4.1 7.2 6.1 2.3 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 Spt20 PF12090.8 OQS02535.1 - 5.1 6.6 9.5 9.4 5.8 2.2 2.5 2 0 0 2 2 2 0 Spt20 family Presenilin PF01080.17 OQS02535.1 - 7.9 5.1 6.9 24 3.5 3.1 2.1 2 0 0 2 2 2 0 Presenilin RNA_polI_A34 PF08208.11 OQS02535.1 - 8.8 6.4 29.3 7.8 6.5 14.2 2.5 2 0 0 2 2 2 0 DNA-directed RNA polymerase I subunit RPA34.5 DCP2 PF05026.13 OQS02536.1 - 1.5e-26 92.5 5.5 2.9e-26 91.6 5.5 1.5 1 0 0 1 1 1 1 Dcp2, box A domain NUDIX PF00293.28 OQS02536.1 - 1.5e-13 50.9 0.0 3e-13 50.0 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain DnaJ PF00226.31 OQS02537.1 - 0.0075 16.4 0.0 0.025 14.7 0.0 1.9 1 0 0 1 1 1 1 DnaJ domain PrmA PF06325.13 OQS02538.1 - 2.3e-08 33.8 0.3 3.3e-08 33.3 0.3 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_16 PF10294.9 OQS02538.1 - 3.2e-08 33.5 0.0 5.1e-08 32.8 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase MTS PF05175.14 OQS02538.1 - 0.00062 19.4 0.1 0.00099 18.7 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Cons_hypoth95 PF03602.15 OQS02538.1 - 0.04 13.5 0.0 0.053 13.2 0.0 1.2 1 0 0 1 1 1 0 Conserved hypothetical protein 95 PAP_assoc PF03828.19 OQS02539.1 - 6.9e-16 58.2 0.0 3.8e-15 55.9 0.0 2.2 2 0 0 2 2 2 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 OQS02539.1 - 4.6e-08 33.2 0.0 1.9e-07 31.3 0.0 2.1 1 1 0 1 1 1 1 Nucleotidyltransferase domain Polbeta PF18765.1 OQS02539.1 - 0.00023 21.2 0.0 0.00066 19.7 0.0 1.7 1 0 0 1 1 1 1 Polymerase beta, Nucleotidyltransferase Nrap_D2 PF17403.2 OQS02539.1 - 0.11 12.2 0.0 0.2 11.4 0.0 1.4 1 0 0 1 1 1 0 Nrap protein PAP/OAS-like domain YIF1 PF03878.15 OQS02540.1 - 1e-59 202.0 2.5 1.6e-59 201.4 2.5 1.2 1 0 0 1 1 1 1 YIF1 tRNA_bind PF01588.20 OQS02540.1 - 6.2e-28 96.8 0.0 1.1e-27 96.0 0.0 1.4 1 0 0 1 1 1 1 Putative tRNA binding domain GST_C_2 PF13410.6 OQS02540.1 - 6.5e-06 26.1 0.2 1.5e-05 25.0 0.2 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Yip1 PF04893.17 OQS02540.1 - 1.6e-05 24.7 2.8 3.2e-05 23.7 2.8 1.5 1 0 0 1 1 1 1 Yip1 domain GST_C PF00043.25 OQS02540.1 - 6.3e-05 23.1 0.0 6.3e-05 23.1 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_6 PF17171.4 OQS02540.1 - 0.017 14.9 0.0 0.04 13.7 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain SAPS PF04499.15 OQS02540.1 - 1.4 7.6 3.6 2 7.1 3.6 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein RNA_pol_Rpc4 PF05132.14 OQS02540.1 - 2.1 8.8 8.8 6 7.3 8.8 1.7 1 0 0 1 1 1 0 RNA polymerase III RPC4 Zip PF02535.22 OQS02540.1 - 2.6 7.2 7.2 4.5 6.4 7.2 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter RR_TM4-6 PF06459.12 OQS02540.1 - 2.7 7.8 9.4 5.2 6.8 9.4 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Fis1_TPR_C PF14853.6 OQS02541.1 - 5.4e-11 42.4 0.6 1.1e-10 41.5 0.6 1.5 1 0 0 1 1 1 1 Fis1 C-terminal tetratricopeptide repeat TPR_2 PF07719.17 OQS02541.1 - 0.0019 18.2 2.5 0.0025 17.8 0.3 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 OQS02541.1 - 0.0055 16.8 0.2 0.015 15.4 0.2 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat ANAPC3 PF12895.7 OQS02541.1 - 0.046 14.0 4.8 0.077 13.2 4.3 1.6 1 1 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 Cornichon PF03311.14 OQS02542.1 - 7.9e-32 110.1 1.9 9.4e-32 109.9 1.9 1.1 1 0 0 1 1 1 1 Cornichon protein Cullin PF00888.22 OQS02543.1 - 7.2e-138 460.9 2.8 1.1e-137 460.3 2.8 1.2 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 OQS02543.1 - 6e-19 67.9 0.7 6e-19 67.9 0.7 2.7 3 0 0 3 3 3 1 Cullin protein neddylation domain DUF5085 PF16895.5 OQS02543.1 - 0.026 14.9 0.2 0.22 11.8 0.0 2.7 2 1 0 3 3 3 0 Domain of unknown function (DUF5085) DAGAT PF03982.13 OQS02544.1 - 3.1e-51 174.1 0.0 3.6e-51 173.8 0.0 1.0 1 0 0 1 1 1 1 Diacylglycerol acyltransferase DIE2_ALG10 PF04922.12 OQS02545.1 - 3e-104 349.5 33.9 7.2e-104 348.2 33.9 1.6 1 1 0 1 1 1 1 DIE2/ALG10 family DUF2637 PF10935.8 OQS02545.1 - 0.0093 15.9 0.1 0.026 14.4 0.1 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF2637) PseudoU_synth_1 PF01416.20 OQS02546.1 - 4.2e-41 139.8 0.1 3.8e-29 101.3 0.0 2.1 2 0 0 2 2 2 2 tRNA pseudouridine synthase Sel1 PF08238.12 OQS02547.1 - 3.5e-28 97.4 10.7 7.1e-05 23.3 0.2 7.0 6 1 0 6 6 6 6 Sel1 repeat CoA_trans PF01144.23 OQS02547.1 - 0.16 11.4 0.0 0.22 10.9 0.0 1.4 1 0 0 1 1 1 0 Coenzyme A transferase TPR_19 PF14559.6 OQS02547.1 - 4.4 7.9 10.4 23 5.6 0.1 4.1 4 1 0 4 4 4 0 Tetratricopeptide repeat zf-NOSIP PF15906.5 OQS02549.1 - 2e-10 40.6 0.1 3.8e-10 39.8 0.1 1.5 1 0 0 1 1 1 1 Zinc-finger of nitric oxide synthase-interacting protein Rtf2 PF04641.12 OQS02549.1 - 1.8e-05 24.3 2.2 0.00095 18.6 0.0 2.2 2 0 0 2 2 2 2 Rtf2 RING-finger zf-RING_2 PF13639.6 OQS02549.1 - 0.013 15.8 1.0 2.1 8.8 0.1 2.4 2 0 0 2 2 2 0 Ring finger domain DUF2093 PF09866.9 OQS02549.1 - 0.045 13.2 0.0 0.13 11.8 0.0 1.8 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2093) Semialdhyde_dhC PF02774.18 OQS02549.1 - 0.1 12.7 0.1 0.14 12.2 0.1 1.3 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, dimerisation domain zf-RING_UBOX PF13445.6 OQS02549.1 - 0.14 12.2 2.9 0.16 12.0 0.3 2.3 2 0 0 2 2 2 0 RING-type zinc-finger DNA_pol3_a_NII PF11490.8 OQS02549.1 - 1.1 9.1 9.7 0.1 12.5 3.4 2.2 3 0 0 3 3 3 0 DNA polymerase III polC-type N-terminus II Wbp11 PF09429.10 OQS02549.1 - 5.1 7.6 11.3 22 5.5 11.4 2.0 1 1 0 1 1 1 0 WW domain binding protein 11 Aminotran_1_2 PF00155.21 OQS02551.1 - 5.5e-55 187.0 0.0 7.9e-55 186.5 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 OQS02551.1 - 0.00042 19.0 0.0 0.0034 16.0 0.0 2.0 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 OQS02551.1 - 0.004 16.2 0.0 0.054 12.5 0.0 2.1 1 1 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 OQS02551.1 - 0.024 13.9 0.0 0.036 13.4 0.0 1.2 1 0 0 1 1 1 0 Beta-eliminating lyase Aminotran_MocR PF12897.7 OQS02551.1 - 0.089 11.6 0.0 0.31 9.8 0.0 1.9 2 0 0 2 2 2 0 Alanine-glyoxylate amino-transferase Methyltransf_16 PF10294.9 OQS02552.1 - 1.7e-36 125.6 0.0 2.6e-36 125.0 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase TPR_2 PF07719.17 OQS02552.1 - 9.5e-08 31.6 8.2 4.5e-05 23.2 0.6 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 OQS02552.1 - 2e-07 30.5 6.2 0.0018 18.0 0.6 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat PrmA PF06325.13 OQS02552.1 - 6.7e-06 25.7 0.0 1.3e-05 24.8 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) TPR_16 PF13432.6 OQS02552.1 - 3.1e-05 24.5 9.7 0.021 15.5 2.3 2.8 2 1 1 3 3 3 2 Tetratricopeptide repeat MTS PF05175.14 OQS02552.1 - 0.0025 17.4 0.0 0.0051 16.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain TPR_12 PF13424.6 OQS02552.1 - 0.021 15.1 1.0 0.021 15.1 1.0 2.5 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_11 PF13414.6 OQS02552.1 - 0.095 12.4 1.9 0.12 12.1 0.2 2.1 2 0 0 2 2 2 0 TPR repeat Methyltransf_23 PF13489.6 OQS02552.1 - 0.13 12.1 0.0 0.26 11.1 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain TPR_8 PF13181.6 OQS02552.1 - 0.36 11.2 5.0 3.3 8.2 0.2 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 OQS02552.1 - 0.36 11.8 8.7 11 7.1 0.2 3.6 2 1 1 3 3 3 0 Tetratricopeptide repeat TTL PF03133.15 OQS02553.1 - 5.5e-63 212.8 0.0 9.3e-63 212.1 0.0 1.4 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 OQS02553.1 - 9.2e-09 34.9 0.7 5.1e-06 25.9 0.0 3.3 3 1 1 4 4 4 2 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 OQS02553.1 - 0.0024 17.2 0.0 0.037 13.3 0.0 2.1 2 0 0 2 2 2 1 Sugar-transfer associated ATP-grasp tRNA_anti-codon PF01336.25 OQS02554.1 - 0.0051 16.8 0.0 0.058 13.4 0.0 2.5 2 1 0 2 2 2 1 OB-fold nucleic acid binding domain Choline_transpo PF04515.12 OQS02555.1 - 1.1e-75 254.9 22.3 1.1e-75 254.9 22.3 2.3 2 1 0 2 2 2 1 Plasma-membrane choline transporter zf-C3Hc3H PF13891.6 OQS02555.1 - 0.025 14.9 2.4 0.32 11.4 0.7 2.5 2 0 0 2 2 2 0 Potential DNA-binding domain MFS_1 PF07690.16 OQS02556.1 - 2.8e-19 69.3 33.5 2.1e-11 43.4 12.3 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 OQS02556.1 - 1.6e-15 56.6 21.1 2.7e-14 52.6 6.5 3.0 2 1 1 3 3 3 2 MFS/sugar transport protein UL42 PF17638.2 OQS02556.1 - 3.1 7.8 4.8 13 5.8 0.1 3.2 3 0 0 3 3 3 0 HCMV UL42 DUF4231 PF14015.6 OQS02556.1 - 3.1 8.3 8.5 5.4 7.5 3.4 3.5 3 1 0 3 3 3 0 Protein of unknown function (DUF4231) APH PF01636.23 OQS02557.1 - 1.6e-41 142.8 0.0 2.6e-41 142.1 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Acyl-CoA_dh_1 PF00441.24 OQS02557.1 - 1.1e-34 119.8 6.1 2.3e-34 118.8 6.1 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 OQS02557.1 - 1e-17 64.1 0.0 2.2e-17 63.0 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 OQS02557.1 - 6.3e-12 45.9 2.8 1.4e-11 44.8 2.8 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 OQS02557.1 - 3.9e-10 40.4 0.0 9e-10 39.2 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Choline_kinase PF01633.20 OQS02557.1 - 0.0024 17.5 0.0 0.0048 16.5 0.0 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.22 OQS02557.1 - 0.066 12.8 0.0 6.3 6.3 0.0 2.5 2 0 0 2 2 2 0 RIO1 family EcKinase PF02958.20 OQS02557.1 - 0.16 11.2 0.0 0.41 9.9 0.0 1.6 1 0 0 1 1 1 0 Ecdysteroid kinase zf-C6H2 PF15801.5 OQS02557.1 - 0.47 10.8 2.6 1.5 9.2 2.6 1.8 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding Xrn1_D3 PF18194.1 OQS02558.1 - 0.023 14.8 0.0 0.05 13.7 0.0 1.5 2 0 0 2 2 2 0 Exoribonuclease 1 Domain-3 Pro-kuma_activ PF09286.11 OQS02559.1 - 8.1e-12 45.6 0.2 2e-11 44.4 0.1 1.8 2 0 0 2 2 2 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 OQS02559.1 - 0.00013 21.3 0.1 0.0002 20.7 0.1 1.2 1 0 0 1 1 1 1 Subtilase family NAD_binding_8 PF13450.6 OQS02560.1 - 1.4e-16 60.4 0.7 4e-15 55.8 0.1 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 OQS02560.1 - 8.1e-14 51.7 0.2 3.7e-12 46.3 0.1 2.8 2 1 0 2 2 2 1 Flavin containing amine oxidoreductase DAO PF01266.24 OQS02560.1 - 9.8e-10 38.5 1.8 1.9e-05 24.5 1.6 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 OQS02560.1 - 2.4e-09 36.8 0.8 7.2e-08 31.9 1.0 2.2 2 0 0 2 2 2 1 FAD binding domain GDI PF00996.18 OQS02560.1 - 2.5e-06 26.3 0.2 0.012 14.2 0.1 2.3 2 0 0 2 2 2 2 GDP dissociation inhibitor FAD_oxidored PF12831.7 OQS02560.1 - 9.9e-06 25.1 1.0 1.7e-05 24.3 1.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 OQS02560.1 - 5.6e-05 22.5 0.3 0.00011 21.5 0.3 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 OQS02560.1 - 7.4e-05 22.1 0.1 7.4e-05 22.1 0.1 2.3 3 0 0 3 3 3 1 Thi4 family FAD_binding_3 PF01494.19 OQS02560.1 - 0.00032 20.1 1.6 0.00056 19.3 1.6 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.27 OQS02560.1 - 0.0016 19.0 1.3 0.0067 17.0 1.1 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 OQS02560.1 - 0.0019 17.3 0.1 0.092 11.8 0.0 2.1 2 0 0 2 2 2 1 Lycopene cyclase protein HI0933_like PF03486.14 OQS02560.1 - 0.0021 16.9 0.6 0.0032 16.2 0.6 1.3 1 0 0 1 1 1 1 HI0933-like protein MCRA PF06100.11 OQS02560.1 - 0.014 14.2 0.1 0.021 13.6 0.1 1.2 1 0 0 1 1 1 0 MCRA family GIDA PF01134.22 OQS02560.1 - 0.054 12.6 0.7 0.14 11.2 0.4 1.8 2 0 0 2 2 2 0 Glucose inhibited division protein A AlaDh_PNT_C PF01262.21 OQS02560.1 - 0.059 12.7 0.0 0.12 11.6 0.0 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain ADH_zinc_N PF00107.26 OQS02561.1 - 5.9e-19 68.3 0.4 1.1e-18 67.5 0.4 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 OQS02561.1 - 6e-07 29.3 0.1 8.3e-05 22.4 0.0 3.1 3 1 1 4 4 4 1 Alcohol dehydrogenase GroES-like domain Peripla_BP_4 PF13407.6 OQS02561.1 - 0.00011 21.9 1.8 0.00068 19.3 0.4 2.1 1 1 1 2 2 2 1 Periplasmic binding protein domain TrkA_N PF02254.18 OQS02561.1 - 0.00022 21.5 0.5 0.0004 20.6 0.5 1.4 1 0 0 1 1 1 1 TrkA-N domain ADH_zinc_N_2 PF13602.6 OQS02561.1 - 0.00027 22.0 0.3 0.0013 19.8 0.0 2.0 2 0 0 2 2 2 1 Zinc-binding dehydrogenase NAD_binding_10 PF13460.6 OQS02561.1 - 0.0023 17.8 0.1 0.0039 17.1 0.1 1.3 1 0 0 1 1 1 1 NAD(P)H-binding adh_short PF00106.25 OQS02561.1 - 0.0048 16.4 0.4 0.0078 15.7 0.4 1.3 1 0 0 1 1 1 1 short chain dehydrogenase NmrA PF05368.13 OQS02561.1 - 0.014 14.9 0.2 0.025 14.1 0.2 1.3 1 0 0 1 1 1 0 NmrA-like family NAD_binding_2 PF03446.15 OQS02561.1 - 0.02 15.0 0.1 0.039 14.1 0.1 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase ADH_N_2 PF16884.5 OQS02561.1 - 0.028 14.3 0.0 0.056 13.3 0.0 1.6 1 1 0 1 1 1 0 N-terminal domain of oxidoreductase ApbA PF02558.16 OQS02561.1 - 0.062 13.0 0.1 0.1 12.3 0.1 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA CoA_binding_2 PF13380.6 OQS02561.1 - 0.062 13.8 0.2 0.18 12.3 0.2 1.8 1 1 0 1 1 1 0 CoA binding domain TraP PF07296.11 OQS02561.1 - 0.082 12.1 0.1 0.18 11.0 0.1 1.5 1 0 0 1 1 1 0 TraP protein DapB_N PF01113.20 OQS02561.1 - 0.14 12.3 1.5 2.3 8.3 0.5 2.5 2 1 1 3 3 3 0 Dihydrodipicolinate reductase, N-terminus HlyD PF00529.20 OQS02561.1 - 0.14 12.0 0.1 0.5 10.3 0.1 1.9 1 1 1 2 2 2 0 HlyD membrane-fusion protein of T1SS DNA_RNApol_7kD PF03604.13 OQS02562.1 - 6.6e-14 51.3 6.7 1.1e-13 50.6 6.7 1.4 1 0 0 1 1 1 1 DNA directed RNA polymerase, 7 kDa subunit Nudix_N_2 PF14803.6 OQS02562.1 - 0.0062 16.4 0.5 0.63 10.0 0.0 2.2 2 0 0 2 2 2 2 Nudix N-terminal DUF2318 PF10080.9 OQS02562.1 - 0.065 13.4 0.3 0.077 13.1 0.3 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2318) zinc_ribbon_13 PF09855.9 OQS02562.1 - 0.11 12.7 0.8 0.16 12.2 0.1 1.5 1 1 0 1 1 1 0 Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082) Aldedh PF00171.22 OQS02563.1 - 3.1e-38 131.5 0.0 9.7e-38 129.8 0.0 1.7 2 0 0 2 2 2 1 Aldehyde dehydrogenase family U3_assoc_6 PF08640.11 OQS02563.1 - 2.2e-28 98.1 5.1 2.2e-28 98.1 5.1 2.1 2 0 0 2 2 2 1 U3 small nucleolar RNA-associated protein 6 TPR_14 PF13428.6 OQS02563.1 - 3.8e-10 39.7 5.1 0.61 11.1 1.1 6.9 6 1 0 6 6 6 4 Tetratricopeptide repeat TPR_19 PF14559.6 OQS02563.1 - 0.00062 20.2 0.0 2.7 8.5 0.0 4.6 5 1 0 5 5 5 2 Tetratricopeptide repeat NRDE-2 PF08424.10 OQS02563.1 - 0.0016 17.6 14.8 0.0069 15.5 1.1 3.8 3 2 1 4 4 4 2 NRDE-2, necessary for RNA interference NTP_transferase PF00483.23 OQS02564.1 - 1.7e-39 135.9 0.0 1.9e-19 70.3 0.0 2.1 1 1 1 2 2 2 2 Nucleotidyl transferase Hexapep PF00132.24 OQS02564.1 - 2.4e-10 39.7 8.0 6.3e-07 28.9 1.7 3.1 1 1 1 2 2 2 2 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.7 OQS02564.1 - 5.6e-06 26.8 0.0 7.7e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep_2 PF14602.6 OQS02564.1 - 0.003 17.3 2.7 0.003 17.3 2.7 3.2 3 1 0 3 3 3 1 Hexapeptide repeat of succinyl-transferase PGM_PMM_I PF02878.16 OQS02564.1 - 0.074 12.8 0.0 0.19 11.5 0.0 1.7 2 0 0 2 2 2 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I Fucokinase PF07959.12 OQS02564.1 - 0.11 11.4 0.0 0.46 9.4 0.0 1.9 2 1 0 2 2 2 0 L-fucokinase Ribosomal_S25 PF03297.15 OQS02565.1 - 3.3e-37 126.7 4.1 3.6e-37 126.6 4.1 1.0 1 0 0 1 1 1 1 S25 ribosomal protein EAP30 PF04157.16 OQS02565.1 - 0.029 13.7 0.1 0.035 13.4 0.1 1.1 1 0 0 1 1 1 0 EAP30/Vps36 family HTH_11 PF08279.12 OQS02565.1 - 0.035 14.1 0.1 0.055 13.4 0.1 1.3 1 0 0 1 1 1 0 HTH domain MarR PF01047.22 OQS02565.1 - 0.04 13.9 0.1 0.054 13.4 0.1 1.2 1 0 0 1 1 1 0 MarR family TrmB PF01978.19 OQS02565.1 - 0.054 13.4 0.1 0.067 13.1 0.1 1.3 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB AAA_14 PF13173.6 OQS02566.1 - 1.1e-05 25.5 0.0 1.5e-05 25.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 OQS02566.1 - 0.0001 22.7 0.0 0.00017 22.0 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ATPase_2 PF01637.18 OQS02566.1 - 0.00011 22.2 0.0 0.00014 21.9 0.0 1.3 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_35 PF14516.6 OQS02566.1 - 0.00041 19.3 0.1 0.12 11.2 0.3 2.2 1 1 1 2 2 2 2 AAA-like domain AAA_22 PF13401.6 OQS02566.1 - 0.016 15.5 0.0 0.87 9.9 0.0 2.2 1 1 1 2 2 2 0 AAA domain AAA_23 PF13476.6 OQS02566.1 - 0.038 14.5 0.1 0.15 12.6 0.1 1.9 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.6 OQS02566.1 - 0.11 12.8 0.0 3 8.2 0.0 2.1 1 1 1 2 2 2 0 AAA ATPase domain UFD1 PF03152.14 OQS02567.1 - 3e-29 101.7 0.0 6.5e-29 100.6 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 zf-C2HC_2 PF13913.6 OQS02567.1 - 4 7.4 7.8 0.64 10.0 0.8 3.2 2 0 0 2 2 2 0 zinc-finger of a C2HC-type WD40 PF00400.32 OQS02569.1 - 2.4e-10 40.8 11.0 1.2 10.1 0.2 6.3 5 0 0 5 5 5 5 WD domain, G-beta repeat Sec16_C PF12931.7 OQS02569.1 - 3.6e-09 36.7 0.2 7.2e-08 32.4 0.2 2.3 1 1 0 1 1 1 1 Sec23-binding domain of Sec16 ANAPC4_WD40 PF12894.7 OQS02569.1 - 6.9e-05 23.1 0.5 1.8 8.9 0.0 4.2 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain SRA1 PF07304.11 OQS02569.1 - 0.00011 22.1 0.2 0.00026 20.8 0.2 1.6 1 0 0 1 1 1 1 Steroid receptor RNA activator (SRA1) NMD3 PF04981.13 OQS02570.1 - 3.5e-79 265.7 4.6 5.5e-79 265.1 4.6 1.3 1 0 0 1 1 1 1 NMD3 family DUF4866 PF16160.5 OQS02570.1 - 0.0063 15.9 0.6 0.013 14.8 0.6 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4866) DUF1283 PF06932.11 OQS02570.1 - 1.8 8.9 4.4 21 5.4 2.6 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1283) FoP_duplication PF13865.6 OQS02572.1 - 3.8e-09 37.0 9.2 9.6e-09 35.7 9.2 1.9 1 1 0 1 1 1 1 C-terminal duplication domain of Friend of PRMT1 Adaptin_N PF01602.20 OQS02573.1 - 1.1e-92 311.3 2.2 1.7e-92 310.7 2.2 1.1 1 0 0 1 1 1 1 Adaptin N terminal region AP4E_app_platf PF14807.6 OQS02573.1 - 7.9e-23 80.7 0.0 2.9e-22 78.9 0.0 2.0 1 0 0 1 1 1 1 Adaptin AP4 complex epsilon appendage platform Cnd1 PF12717.7 OQS02573.1 - 1.5e-09 38.1 0.1 1.3e-08 35.1 0.0 2.4 2 1 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 OQS02573.1 - 0.00061 20.1 0.7 0.097 13.1 0.0 3.7 3 0 0 3 3 3 1 HEAT repeats HEAT_EZ PF13513.6 OQS02573.1 - 0.013 16.0 2.7 9.8 6.8 0.4 4.1 3 1 1 4 4 4 0 HEAT-like repeat HEAT PF02985.22 OQS02573.1 - 0.027 14.7 0.4 0.81 10.1 0.0 3.6 3 0 0 3 3 3 0 HEAT repeat TFIID-31kDa PF02291.15 OQS02574.1 - 2.4e-40 137.4 0.3 3.5e-40 136.9 0.3 1.2 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Histone PF00125.24 OQS02574.1 - 0.02 15.3 0.2 0.037 14.4 0.2 1.5 1 0 0 1 1 1 0 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 OQS02574.1 - 0.029 14.7 0.0 0.054 13.9 0.0 1.4 1 0 0 1 1 1 0 CENP-S protein Lipase_GDSL_2 PF13472.6 OQS02575.1 - 3.3e-09 37.4 0.0 4.3e-09 37.0 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 OQS02575.1 - 0.089 12.8 0.0 0.11 12.5 0.0 1.1 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase Tfb4 PF03850.14 OQS02575.1 - 0.11 12.0 0.0 0.16 11.5 0.0 1.2 1 0 0 1 1 1 0 Transcription factor Tfb4 RCC1 PF00415.18 OQS02576.1 - 5.2e-134 436.8 35.4 2.1e-14 53.8 0.1 14.7 14 0 0 14 14 14 14 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 OQS02576.1 - 6.4e-60 197.9 62.9 1.2e-08 34.5 1.0 16.0 15 0 0 15 15 15 13 Regulator of chromosome condensation (RCC1) repeat SPRY PF00622.28 OQS02576.1 - 7.6e-57 190.6 0.5 1.1e-19 70.7 0.0 5.8 5 0 0 5 5 5 5 SPRY domain HECT PF00632.25 OQS02576.1 - 2.4e-56 191.5 0.0 4.3e-56 190.6 0.0 1.4 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Kelch_4 PF13418.6 OQS02576.1 - 2.2e-29 101.2 8.5 1e-07 31.9 0.3 7.1 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_5 PF13854.6 OQS02576.1 - 6.5e-21 73.9 1.1 9.7e-05 22.3 0.0 6.7 6 0 0 6 6 6 5 Kelch motif Kelch_3 PF13415.6 OQS02576.1 - 6.2e-18 64.6 1.9 0.0072 16.6 0.1 6.3 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_6 PF13964.6 OQS02576.1 - 1.2e-17 63.5 22.2 0.0002 21.5 0.0 9.2 9 1 1 10 10 9 3 Kelch motif FHA PF00498.26 OQS02576.1 - 5.4e-13 49.1 1.1 1.7e-12 47.5 1.1 2.0 1 0 0 1 1 1 1 FHA domain Kelch_2 PF07646.15 OQS02576.1 - 1.8e-11 43.5 16.5 0.0004 20.3 0.1 6.3 6 0 0 6 6 6 2 Kelch motif Kelch_1 PF01344.25 OQS02576.1 - 3.2e-11 42.6 15.4 0.0028 17.2 0.8 6.9 7 0 0 7 7 7 3 Kelch motif Yop-YscD_cpl PF16697.5 OQS02576.1 - 1.8e-09 37.8 0.0 5.1e-09 36.3 0.0 1.7 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain Vps62 PF06101.11 OQS02576.1 - 2e-05 23.1 0.0 3.3e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 62 UBA PF00627.31 OQS02576.1 - 0.00066 19.5 0.0 0.0074 16.2 0.0 2.6 2 0 0 2 2 2 1 UBA/TS-N domain PUL PF08324.11 OQS02576.1 - 0.0023 17.2 0.5 0.0023 17.2 0.5 2.0 2 0 0 2 2 2 1 PUL domain Ank_2 PF12796.7 OQS02577.1 - 1.5e-06 28.7 0.2 3.2e-06 27.6 0.2 1.5 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OQS02577.1 - 1.1e-05 25.4 0.0 0.067 13.8 0.0 3.2 2 1 1 3 3 3 1 Ankyrin repeat Ank_4 PF13637.6 OQS02577.1 - 9.6e-05 22.9 0.2 0.59 10.8 0.2 2.7 2 1 0 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 OQS02577.1 - 0.015 15.6 0.1 0.081 13.3 0.0 2.1 2 1 1 3 3 3 0 Ankyrin repeats (many copies) DUF249 PF03158.13 OQS02577.1 - 0.027 14.2 0.1 5.2 6.7 0.0 2.0 1 1 0 2 2 2 0 Multigene family 530 protein Ank PF00023.30 OQS02577.1 - 0.16 12.5 0.0 3.7 8.2 0.0 2.8 1 1 0 1 1 1 0 Ankyrin repeat HSF_DNA-bind PF00447.17 OQS02578.1 - 3e-47 159.2 10.7 4.7e-25 88.0 0.4 2.2 2 0 0 2 2 2 2 HSF-type DNA-binding DUF2407_C PF13373.6 OQS02579.1 - 1.2e-22 80.6 0.1 2.1e-22 79.8 0.1 1.4 1 0 0 1 1 1 1 DUF2407 C-terminal domain PH PF00169.29 OQS02579.1 - 1.1e-17 64.4 0.2 2.2e-17 63.5 0.2 1.5 1 0 0 1 1 1 1 PH domain ubiquitin PF00240.23 OQS02579.1 - 1.8e-13 50.1 0.1 3.8e-13 49.0 0.1 1.6 1 0 0 1 1 1 1 Ubiquitin family DUF2407 PF10302.9 OQS02579.1 - 3.7e-07 30.7 0.0 7.7e-07 29.6 0.0 1.5 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain PH_3 PF14593.6 OQS02579.1 - 4e-05 23.7 0.0 9.1e-05 22.5 0.0 1.5 1 0 0 1 1 1 1 PH domain Thioredoxin_8 PF13905.6 OQS02579.1 - 4.5e-05 23.7 0.0 0.00024 21.3 0.0 2.2 2 0 0 2 2 2 1 Thioredoxin-like Rad60-SLD PF11976.8 OQS02579.1 - 0.00077 19.3 0.1 0.0017 18.2 0.1 1.6 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like PH_9 PF15410.6 OQS02579.1 - 0.0018 18.6 0.2 0.038 14.4 0.2 2.3 1 1 0 1 1 1 1 Pleckstrin homology domain Rad60-SLD_2 PF13881.6 OQS02579.1 - 0.003 17.6 0.1 0.0069 16.5 0.1 1.6 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like PH_8 PF15409.6 OQS02579.1 - 0.0066 16.7 0.1 0.014 15.7 0.1 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain PH_11 PF15413.6 OQS02579.1 - 0.0095 16.3 1.8 0.12 12.8 1.8 2.3 1 1 0 1 1 1 1 Pleckstrin homology domain PH_13 PF16652.5 OQS02579.1 - 0.04 13.7 0.0 0.094 12.5 0.0 1.5 1 0 0 1 1 1 0 Pleckstrin homology domain PH_2 PF08458.10 OQS02579.1 - 0.04 14.3 0.1 0.13 12.7 0.1 1.8 1 1 0 1 1 1 0 Plant pleckstrin homology-like region Ubiquitin_4 PF18036.1 OQS02579.1 - 0.071 13.2 5.9 0.38 10.8 0.3 3.1 2 1 1 3 3 3 0 Ubiquitin-like domain DUF2228 PF10228.9 OQS02579.1 - 0.071 12.8 0.2 0.21 11.3 0.1 1.7 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2228) Arm PF00514.23 OQS02580.1 - 1.3e-85 279.1 21.2 1.3e-11 44.1 0.0 9.6 9 0 0 9 9 9 8 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 OQS02580.1 - 9.1e-26 89.9 2.8 3e-10 40.4 0.0 6.6 4 2 2 6 6 6 5 HEAT-like repeat IBB PF01749.20 OQS02580.1 - 2.7e-20 72.6 3.1 6.8e-20 71.3 3.1 1.7 1 0 0 1 1 1 1 Importin beta binding domain Arm_3 PF16186.5 OQS02580.1 - 1.1e-19 69.7 0.3 1.1e-18 66.5 0.7 2.4 2 0 0 2 2 2 1 Atypical Arm repeat HEAT_2 PF13646.6 OQS02580.1 - 3.7e-17 62.5 0.1 9.9e-05 22.7 0.0 5.5 1 1 3 5 5 5 5 HEAT repeats HEAT PF02985.22 OQS02580.1 - 1.5e-15 55.9 4.2 0.0014 18.7 0.0 9.2 9 0 0 9 9 9 3 HEAT repeat IQ PF00612.27 OQS02580.1 - 0.00061 19.4 4.3 0.27 11.1 0.3 2.9 2 0 0 2 2 2 2 IQ calmodulin-binding motif V-ATPase_H_C PF11698.8 OQS02580.1 - 0.00086 19.4 0.6 5.1 7.2 0.0 4.7 4 1 2 6 6 6 2 V-ATPase subunit H RICTOR_V PF14668.6 OQS02580.1 - 0.00097 19.3 1.0 0.46 10.8 0.0 4.2 3 2 1 4 4 4 1 Rapamycin-insensitive companion of mTOR, domain 5 HEAT_PBS PF03130.16 OQS02580.1 - 0.0011 19.4 1.1 12 6.9 0.0 6.2 7 0 0 7 7 6 1 PBS lyase HEAT-like repeat Cnd1 PF12717.7 OQS02580.1 - 0.0013 18.8 0.0 2.7 8.0 0.0 3.5 1 1 3 4 4 4 1 non-SMC mitotic condensation complex subunit 1 Mo25 PF08569.11 OQS02580.1 - 0.0051 16.2 0.6 0.98 8.7 0.0 2.8 3 0 0 3 3 3 1 Mo25-like CTNNBL PF08216.11 OQS02580.1 - 0.0092 16.1 0.5 1.9 8.7 0.1 4.5 5 0 0 5 5 5 1 Catenin-beta-like, Arm-motif containing nuclear DUF3361 PF11841.8 OQS02580.1 - 0.052 13.5 0.7 4.3 7.2 0.0 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF3361) Atx10homo_assoc PF09759.9 OQS02580.1 - 0.096 12.7 0.2 15 5.7 0.0 3.5 3 0 0 3 3 3 0 Spinocerebellar ataxia type 10 protein domain Elicitin PF00964.17 OQS02582.1 - 3.7e-06 26.9 2.2 5.1e-06 26.5 1.3 1.7 1 1 0 1 1 1 1 Elicitin CENP-N PF05238.13 OQS02583.1 - 0.017 14.5 0.1 0.017 14.4 0.1 1.0 1 0 0 1 1 1 0 Kinetochore protein CHL4 like DUF2502 PF10697.9 OQS02583.1 - 0.18 12.1 2.4 0.25 11.7 2.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2502) DUF4715 PF15835.5 OQS02584.1 - 0.027 14.5 0.5 0.032 14.3 0.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4715) Phage_prot_Gp6 PF05133.14 OQS02584.1 - 0.064 12.3 1.2 0.07 12.2 1.2 1.0 1 0 0 1 1 1 0 Phage portal protein, SPP1 Gp6-like CK_II_beta PF01214.18 OQS02585.1 - 1.9e-78 262.5 0.0 2.9e-78 261.8 0.0 1.3 1 0 0 1 1 1 1 Casein kinase II regulatory subunit ELO PF01151.18 OQS02585.1 - 4.7e-45 154.1 30.6 7.4e-45 153.4 30.6 1.3 1 0 0 1 1 1 1 GNS1/SUR4 family CENP-B_dimeris PF09026.10 OQS02585.1 - 1.4 9.4 14.7 3.8 7.9 14.7 1.8 1 0 0 1 1 1 0 Centromere protein B dimerisation domain HscB_4_cys PF18256.1 OQS02585.1 - 1.7 8.6 4.4 2.8 7.8 0.2 2.4 2 0 0 2 2 2 0 Co-chaperone HscB tetracysteine metal binding motif DNA_pol_phi PF04931.13 OQS02585.1 - 2 6.4 12.2 3 5.9 12.2 1.1 1 0 0 1 1 1 0 DNA polymerase phi E7 PF00527.18 OQS02585.1 - 4.8 7.4 7.6 2.3 8.5 3.5 2.2 2 0 0 2 2 2 0 E7 protein, Early protein UPF0029 PF01205.19 OQS02586.1 - 9.1e-30 103.1 0.0 1.3e-29 102.6 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 EFG_C PF00679.24 OQS02586.1 - 5.8e-07 29.5 0.0 1.1e-06 28.6 0.0 1.3 1 0 0 1 1 1 1 Elongation factor G C-terminus DUF647 PF04884.14 OQS02586.1 - 0.052 13.2 0.0 0.067 12.8 0.0 1.1 1 0 0 1 1 1 0 Vitamin B6 photo-protection and homoeostasis PHD PF00628.29 OQS02588.1 - 1.4e-31 108.1 145.1 7.8e-08 32.1 10.6 12.0 11 1 1 12 12 12 9 PHD-finger FYRN PF05964.14 OQS02588.1 - 1.8e-19 69.3 0.3 4.5e-19 68.0 0.1 1.9 2 0 0 2 2 2 1 F/Y-rich N-terminus Bromodomain PF00439.25 OQS02588.1 - 2.9e-13 49.7 0.0 7.9e-13 48.3 0.0 1.7 1 0 0 1 1 1 1 Bromodomain SET PF00856.28 OQS02588.1 - 6.5e-13 49.4 0.3 3.8e-12 46.9 0.2 2.5 2 1 0 2 2 2 1 SET domain FYRC PF05965.14 OQS02588.1 - 1.6e-06 28.2 0.0 1e-05 25.6 0.0 2.5 2 0 0 2 2 2 1 F/Y rich C-terminus FUN14 PF04930.15 OQS02589.1 - 6.9e-07 29.6 0.0 2.1e-06 28.1 0.0 1.8 2 0 0 2 2 2 1 FUN14 family PX PF00787.24 OQS02591.1 - 2.3e-20 72.7 0.0 7.2e-20 71.1 0.0 1.9 1 0 0 1 1 1 1 PX domain zf-RING_UBOX PF13445.6 OQS02591.1 - 2.9e-08 33.6 4.6 5.8e-08 32.6 4.6 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_2 PF13639.6 OQS02591.1 - 4.1e-08 33.4 6.4 8.6e-08 32.4 6.4 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 OQS02591.1 - 1.7e-07 31.0 6.5 3.4e-07 30.0 6.5 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OQS02591.1 - 1.7e-06 27.8 6.7 3.7e-06 26.8 6.7 1.6 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 OQS02591.1 - 3.2e-06 26.9 5.4 6.9e-06 25.8 5.4 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 OQS02591.1 - 1e-05 25.6 2.6 3.1e-05 24.1 2.6 1.8 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.6 OQS02591.1 - 2e-05 24.4 4.6 4.2e-05 23.3 4.6 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 OQS02591.1 - 0.0012 18.6 5.8 0.003 17.4 5.8 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 OQS02591.1 - 0.0058 16.9 5.2 0.019 15.3 5.2 1.9 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_4 PF14570.6 OQS02591.1 - 0.0063 16.3 4.9 0.014 15.2 4.9 1.6 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain Spc29 PF17082.5 OQS02591.1 - 0.021 14.6 1.2 0.049 13.5 1.2 1.6 1 0 0 1 1 1 0 Spindle Pole Component 29 zf-RING_11 PF17123.5 OQS02591.1 - 0.061 13.1 2.8 0.16 11.8 2.8 1.8 1 0 0 1 1 1 0 RING-like zinc finger CDCA PF18484.1 OQS02591.1 - 0.072 13.0 0.2 0.15 11.9 0.2 1.5 1 0 0 1 1 1 0 Cadmium carbonic anhydrase repeat FYVE PF01363.21 OQS02591.1 - 0.1 12.7 3.4 0.27 11.4 3.4 1.7 1 0 0 1 1 1 0 FYVE zinc finger Rtf2 PF04641.12 OQS02591.1 - 0.13 11.6 7.0 0.2 11.0 5.9 1.9 1 1 0 1 1 1 0 Rtf2 RING-finger KGK PF08872.10 OQS02591.1 - 0.18 12.3 2.7 0.33 11.5 0.1 2.5 2 0 0 2 2 2 0 KGK domain ASL_C PF08328.11 OQS02591.1 - 0.22 11.6 11.0 0.86 9.7 3.8 3.1 3 1 0 3 3 3 0 Adenylosuccinate lyase C-terminal zf-ANAPC11 PF12861.7 OQS02591.1 - 0.41 10.7 2.7 1.1 9.3 1.0 2.4 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger Peptidase_M61 PF05299.12 OQS02591.1 - 0.58 10.6 0.1 0.58 10.6 0.1 3.2 3 0 0 3 3 3 0 M61 glycyl aminopeptidase NPV_P10 PF05531.12 OQS02591.1 - 1.6 9.2 9.2 3 8.4 0.8 3.1 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein PKD_channel PF08016.12 OQS02592.1 - 2.8e-15 55.9 4.1 4.5e-15 55.3 4.1 1.2 1 0 0 1 1 1 1 Polycystin cation channel Ion_trans PF00520.31 OQS02592.1 - 0.00013 21.3 8.2 0.00017 20.9 8.2 1.2 1 0 0 1 1 1 1 Ion transport protein zf-MYND PF01753.18 OQS02593.1 - 5e-10 39.3 45.3 6.2e-09 35.8 15.3 2.7 2 0 0 2 2 2 2 MYND finger CENP-F_leu_zip PF10473.9 OQS02593.1 - 0.00098 19.2 16.0 0.00098 19.2 16.0 6.3 3 2 3 6 6 6 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 EF-hand_1 PF00036.32 OQS02593.1 - 0.01 15.3 0.0 0.02 14.4 0.0 1.5 1 0 0 1 1 1 0 EF hand Med31 PF05669.12 OQS02593.1 - 0.021 14.8 0.0 0.093 12.7 0.0 2.1 1 0 0 1 1 1 0 SOH1 EF-hand_7 PF13499.6 OQS02593.1 - 0.029 14.8 0.2 0.088 13.3 0.2 1.8 1 0 0 1 1 1 0 EF-hand domain pair XhlA PF10779.9 OQS02593.1 - 7.8 6.8 29.5 0.15 12.3 1.7 7.0 7 1 1 8 8 8 0 Haemolysin XhlA DNA_pol_B PF00136.21 OQS02594.1 - 1.6e-138 462.3 0.1 1.6e-138 462.3 0.1 1.7 2 0 0 2 2 2 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 OQS02594.1 - 4.1e-82 276.0 0.0 6.9e-82 275.3 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain IF-2B PF01008.17 OQS02594.1 - 8e-78 261.5 0.0 1.6e-77 260.5 0.0 1.5 1 0 0 1 1 1 1 Initiation factor 2 subunit family zf-C4pol PF14260.6 OQS02594.1 - 3e-19 69.3 6.9 6.7e-19 68.1 6.9 1.7 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta Acetyltransf_1 PF00583.25 OQS02595.1 - 5.6e-09 36.3 0.0 1.2e-08 35.2 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.10 OQS02595.1 - 1.6e-06 28.0 0.0 3.7e-06 26.8 0.0 1.6 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_3 PF13302.7 OQS02595.1 - 1.7e-05 25.5 0.0 3.1e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 OQS02595.1 - 1.7e-05 24.7 0.0 3e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 OQS02595.1 - 2.9e-05 23.8 0.0 6.9e-05 22.6 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 OQS02595.1 - 4.3e-05 23.9 0.0 0.00012 22.4 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 OQS02595.1 - 0.00039 20.5 0.0 0.00075 19.6 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 OQS02595.1 - 0.018 15.2 0.2 0.063 13.4 0.0 1.9 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain TPR_10 PF13374.6 OQS02596.1 - 0.0046 16.8 0.0 3.3 7.7 0.0 2.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 OQS02596.1 - 0.012 15.9 0.0 1.4 9.3 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat SNAD4 PF18750.1 OQS02596.1 - 0.097 12.8 0.4 14 5.9 0.0 2.4 1 1 1 2 2 2 0 Secreted Novel AID/APOBEC-like Deaminase 4 TERF2_RBM PF16772.5 OQS02596.1 - 0.12 11.8 0.1 11 5.5 0.0 2.5 2 0 0 2 2 2 0 Telomeric repeat-binding factor 2 Rap1-binding motif TPR_14 PF13428.6 OQS02596.1 - 0.14 13.0 0.0 1.2e+02 3.9 0.2 3.5 3 1 1 4 4 4 0 Tetratricopeptide repeat Myb_DNA-binding PF00249.31 OQS02598.1 - 2.7e-12 46.7 0.2 4.2e-12 46.0 0.2 1.3 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OQS02598.1 - 2.8e-05 23.9 0.0 4.5e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 Myb DNA-binding like Myb_DNA-bind_6 PF13921.6 OQS02598.1 - 0.00077 19.7 0.6 0.0013 18.9 0.6 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain GRDP-like PF07173.12 OQS02599.1 - 1.5e-17 64.6 0.2 6.6e-17 62.5 0.2 2.1 1 0 0 1 1 1 1 Glycine-rich domain-containing protein-like PH PF00169.29 OQS02599.1 - 0.074 13.6 0.1 0.2 12.2 0.1 1.7 1 0 0 1 1 1 0 PH domain DEAD PF00270.29 OQS02600.1 - 1.2e-35 122.9 0.2 2.6e-35 121.8 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OQS02600.1 - 3.9e-25 88.4 0.2 1.2e-24 86.8 0.0 2.0 3 0 0 3 3 3 1 Helicase conserved C-terminal domain CMS1 PF14617.6 OQS02600.1 - 0.008 15.5 1.4 0.011 15.1 0.3 1.9 2 1 0 2 2 2 1 U3-containing 90S pre-ribosomal complex subunit Helicase_C_2 PF13307.6 OQS02600.1 - 0.076 13.2 0.0 0.18 11.9 0.0 1.6 1 0 0 1 1 1 0 Helicase C-terminal domain Enkurin PF13864.6 OQS02601.1 - 8.5e-26 90.3 6.6 1.6e-25 89.4 6.6 1.4 1 0 0 1 1 1 1 Calmodulin-binding AAA_13 PF13166.6 OQS02601.1 - 0.0055 15.4 2.3 0.0066 15.1 2.3 1.1 1 0 0 1 1 1 1 AAA domain MscS_porin PF12795.7 OQS02601.1 - 0.025 14.2 1.3 0.041 13.4 1.3 1.3 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain Peptidase_C74 PF12387.8 OQS02602.1 - 0.088 12.3 0.0 0.25 10.8 0.0 1.7 2 0 0 2 2 2 0 Pestivirus NS2 peptidase PAN_4 PF14295.6 OQS02603.1 - 2.5e-35 120.2 63.9 1.1e-06 28.4 3.3 7.6 7 0 0 7 7 7 7 PAN domain PAN_1 PF00024.26 OQS02603.1 - 7.6e-26 89.9 62.1 1.5e-05 24.9 0.8 9.3 6 3 3 9 9 9 6 PAN domain PIG-L PF02585.17 OQS02603.1 - 0.00012 22.7 0.0 0.00022 21.9 0.0 1.5 1 0 0 1 1 1 1 GlcNAc-PI de-N-acetylase PAN_3 PF08277.12 OQS02603.1 - 1.7 8.5 53.7 0.024 14.4 1.6 7.6 7 0 0 7 7 7 0 PAN-like domain p450 PF00067.22 OQS02604.1 - 1.4e-39 136.1 5.2 5.6e-39 134.2 0.0 3.7 3 1 0 3 3 3 1 Cytochrome P450 HPP PF04982.13 OQS02606.1 - 4.4e-77 256.1 23.9 2.9e-41 140.5 3.9 3.4 4 0 0 4 4 4 2 HPP family Phage_holin_3_3 PF16083.5 OQS02606.1 - 0.034 14.3 11.1 3.5 7.8 0.0 5.0 4 1 1 5 5 5 0 LydA holin phage, holin superfamily III DUF2684 PF10885.8 OQS02606.1 - 0.05 13.7 1.2 2.9 8.1 0.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2684) DUF2545 PF10810.8 OQS02606.1 - 9.1 6.5 14.8 0.93 9.7 0.6 3.9 4 1 0 4 4 4 0 Protein of unknown function (DUF2545) DUF3970 PF13113.6 OQS02607.1 - 0.21 11.8 0.1 0.43 10.8 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3970) DUF659 PF04937.15 OQS02608.1 - 0.0014 18.5 1.2 0.0032 17.3 1.2 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) zf-BED PF02892.15 OQS02608.1 - 0.16 12.0 6.9 0.94 9.6 6.9 2.2 1 1 0 1 1 1 0 BED zinc finger Ins_P5_2-kin PF06090.12 OQS02608.1 - 1.7 8.0 3.6 1.9 7.8 3.0 1.6 1 1 1 2 2 2 0 Inositol-pentakisphosphate 2-kinase Sec63 PF02889.16 OQS02609.1 - 1.4e-43 148.9 0.8 2.1e-43 148.4 0.8 1.2 1 0 0 1 1 1 1 Sec63 Brl domain DnaJ PF00226.31 OQS02609.1 - 1.2e-20 73.4 0.0 2.7e-20 72.2 0.0 1.7 1 0 0 1 1 1 1 DnaJ domain Actin PF00022.19 OQS02610.1 - 8e-97 324.4 0.0 2.7e-95 319.4 0.0 2.0 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.13 OQS02610.1 - 5.3e-05 22.2 0.1 0.19 10.5 0.0 2.2 2 0 0 2 2 2 2 MreB/Mbl protein PX PF00787.24 OQS02611.1 - 1.8e-16 60.2 0.2 2.2e-16 59.9 0.2 1.1 1 0 0 1 1 1 1 PX domain Cas_Cas6 PF01881.16 OQS02611.1 - 0.11 13.0 0.0 0.16 12.5 0.0 1.2 1 0 0 1 1 1 0 CRISPR associated protein Cas6 HECT PF00632.25 OQS02612.1 - 4.2e-75 253.1 0.0 7.9e-75 252.2 0.0 1.4 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) CCDC142 PF14923.6 OQS02612.1 - 0.00054 18.8 1.3 0.00075 18.4 0.0 1.7 2 0 0 2 2 2 1 Coiled-coil protein 142 zf-RanBP PF00641.18 OQS02612.1 - 0.042 13.2 1.4 0.088 12.1 1.4 1.5 1 0 0 1 1 1 0 Zn-finger in Ran binding protein and others Hydrolase_3 PF08282.12 OQS02614.1 - 7.1e-46 157.0 0.6 2.2e-44 152.1 0.0 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase SWIRM PF04433.17 OQS02614.1 - 6.3e-28 97.0 0.0 2.1e-27 95.3 0.0 2.0 1 0 0 1 1 1 1 SWIRM domain Lactamase_B_2 PF12706.7 OQS02614.1 - 2.6e-15 56.5 0.4 2.9e-12 46.5 0.1 3.7 4 0 0 4 4 4 2 Beta-lactamase superfamily domain Lactamase_B_4 PF13691.6 OQS02614.1 - 1.6e-13 50.1 0.0 4.5e-13 48.7 0.0 1.9 1 0 0 1 1 1 1 tRNase Z endonuclease SWIRM-assoc_1 PF16495.5 OQS02614.1 - 4.2e-12 45.9 4.0 1.1e-11 44.5 4.0 1.7 1 0 0 1 1 1 1 SWIRM-associated region 1 S6PP PF05116.13 OQS02614.1 - 8.6e-05 22.2 0.0 0.00028 20.5 0.0 1.8 2 0 0 2 2 2 1 Sucrose-6F-phosphate phosphohydrolase Myb_DNA-bind_6 PF13921.6 OQS02614.1 - 0.00052 20.2 0.1 0.0013 19.0 0.1 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 OQS02614.1 - 0.0006 19.9 0.1 0.0016 18.5 0.1 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain Atg29_N PF18388.1 OQS02614.1 - 0.0021 17.8 0.3 0.0054 16.5 0.3 1.7 1 0 0 1 1 1 1 Atg29 N-terminal domain HAD PF12710.7 OQS02614.1 - 0.0033 17.8 0.2 6.5 7.1 0.2 2.9 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 OQS02614.1 - 0.0044 17.3 0.6 0.12 12.7 0.0 3.2 2 2 0 2 2 2 1 haloacid dehalogenase-like hydrolase Lactamase_B PF00753.27 OQS02614.1 - 0.012 15.6 0.0 0.072 13.1 0.1 2.2 2 0 0 2 2 2 0 Metallo-beta-lactamase superfamily WD40 PF00400.32 OQS02614.1 - 0.088 13.7 0.0 1 10.3 0.0 2.8 2 0 0 2 2 2 0 WD domain, G-beta repeat DUF4203 PF13886.6 OQS02615.1 - 3.5e-23 82.3 34.9 5.4e-23 81.7 34.9 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4203) DUF1211 PF06736.11 OQS02615.1 - 0.09 13.2 0.9 0.31 11.5 0.9 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1211) RrnaAD PF00398.20 OQS02616.1 - 3.3e-55 187.0 1.0 4.4e-55 186.6 1.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_25 PF13649.6 OQS02616.1 - 1.9e-07 31.7 0.0 4.3e-07 30.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OQS02616.1 - 0.0001 22.9 0.0 0.00024 21.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OQS02616.1 - 0.00061 19.7 0.0 0.00085 19.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OQS02616.1 - 0.0014 19.3 0.0 0.0027 18.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 OQS02616.1 - 0.0025 17.4 0.0 0.004 16.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain PCMT PF01135.19 OQS02616.1 - 0.0055 16.5 0.0 0.035 13.9 0.0 2.1 2 1 1 3 3 3 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) TctC PF03401.14 OQS02616.1 - 0.0088 15.1 0.1 0.013 14.6 0.1 1.2 1 0 0 1 1 1 1 Tripartite tricarboxylate transporter family receptor TraB PF01963.17 OQS02616.1 - 0.017 15.0 0.1 0.021 14.8 0.1 1.3 1 0 0 1 1 1 0 TraB family DUF4928 PF16280.5 OQS02616.1 - 0.048 12.9 0.1 0.076 12.3 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4928) Methyltransf_31 PF13847.6 OQS02616.1 - 0.05 13.4 0.0 0.099 12.4 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain MPS2 PF17060.5 OQS02617.1 - 1.2e-05 24.8 14.6 2.3e-05 23.8 9.8 2.4 2 0 0 2 2 2 1 Monopolar spindle protein 2 MscS_porin PF12795.7 OQS02617.1 - 4.1e-05 23.2 5.9 4.1e-05 23.2 5.9 3.7 3 1 0 3 3 3 1 Mechanosensitive ion channel porin domain DUF4407 PF14362.6 OQS02617.1 - 0.00034 20.1 25.2 0.0012 18.3 4.9 3.4 2 1 1 3 3 3 2 Domain of unknown function (DUF4407) HEAT_2 PF13646.6 OQS02617.1 - 0.00047 20.5 1.8 3.3 8.2 0.0 4.6 3 1 1 4 4 4 1 HEAT repeats DUF5082 PF16888.5 OQS02617.1 - 0.0041 17.4 1.8 0.0041 17.4 1.8 4.1 3 1 0 3 3 3 1 Domain of unknown function (DUF5082) RTP1_C1 PF10363.9 OQS02617.1 - 0.014 15.6 1.1 0.23 11.7 0.0 3.4 2 0 0 2 2 2 0 Required for nuclear transport of RNA pol II C-terminus 1 SlyX PF04102.12 OQS02617.1 - 0.016 15.8 1.2 0.016 15.8 1.2 7.3 3 2 4 7 7 7 0 SlyX DUF641 PF04859.12 OQS02617.1 - 0.05 13.9 0.2 0.05 13.9 0.2 5.9 3 2 3 7 7 6 0 Plant protein of unknown function (DUF641) HEAT PF02985.22 OQS02617.1 - 0.063 13.6 1.6 12 6.5 0.0 4.0 4 0 0 4 4 3 0 HEAT repeat HOOK PF05622.12 OQS02617.1 - 0.064 11.4 30.0 0.026 12.7 15.6 2.4 1 1 0 2 2 2 0 HOOK protein TMF_DNA_bd PF12329.8 OQS02617.1 - 0.63 10.1 41.2 0.47 10.5 16.1 5.7 3 2 0 4 4 4 0 TATA element modulatory factor 1 DNA binding Nup54_57_C PF18570.1 OQS02617.1 - 0.65 9.6 3.8 3.7 7.2 0.6 2.7 2 0 0 2 2 2 0 NUP57/Nup54 C-terminal domain Spc42p PF11544.8 OQS02617.1 - 0.8 9.7 15.1 11 6.2 6.4 5.2 4 1 0 4 4 4 0 Spindle pole body component Spc42p PKcGMP_CC PF16808.5 OQS02617.1 - 0.93 9.4 29.3 0.29 11.0 0.1 7.4 6 1 0 7 7 7 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Pox_A_type_inc PF04508.12 OQS02617.1 - 1.9 8.5 9.9 17 5.5 0.1 5.5 5 0 0 5 5 5 0 Viral A-type inclusion protein repeat ATG16 PF08614.11 OQS02617.1 - 2.2 8.5 48.1 0.19 12.0 23.0 4.1 3 2 0 3 3 3 0 Autophagy protein 16 (ATG16) Atg14 PF10186.9 OQS02617.1 - 2.5 7.1 22.6 43 3.1 22.3 2.6 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Occludin_ELL PF07303.13 OQS02617.1 - 2.9 8.7 11.2 11 6.8 1.7 4.0 2 2 1 3 3 3 0 Occludin homology domain APG6_N PF17675.1 OQS02617.1 - 2.9 8.4 40.7 0.12 12.9 4.2 4.3 3 1 1 4 4 4 0 Apg6 coiled-coil region Cob_adeno_trans PF01923.18 OQS02617.1 - 3 8.0 10.7 2.4 8.3 4.9 3.2 2 1 0 2 2 2 0 Cobalamin adenosyltransferase DUF812 PF05667.11 OQS02617.1 - 6.3 5.5 31.8 6 5.6 2.8 2.5 1 1 0 2 2 2 0 Protein of unknown function (DUF812) DHR10 PF18595.1 OQS02617.1 - 9.5 6.3 36.2 0.27 11.3 4.4 4.7 4 1 0 4 4 4 0 Designed helical repeat protein 10 domain Fib_alpha PF08702.10 OQS02617.1 - 9.8 6.4 28.5 1.7 8.8 6.5 5.7 2 1 4 6 6 6 0 Fibrinogen alpha/beta chain family DUF1910 PF08928.10 OQS02618.1 - 0.12 12.3 0.0 0.28 11.2 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1910) DUF4203 PF13886.6 OQS02619.1 - 4.6e-26 91.7 32.5 6.8e-26 91.2 32.5 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4203) DAGK_prokar PF01219.19 OQS02619.1 - 0.014 15.2 0.2 0.014 15.2 0.2 3.2 3 1 0 3 3 3 0 Prokaryotic diacylglycerol kinase DUF4026 PF13218.6 OQS02620.1 - 0.086 11.8 0.0 0.5 9.3 0.0 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF4026) FA_desaturase PF00487.24 OQS02621.1 - 1.1e-33 117.1 11.1 1.7e-33 116.5 11.1 1.2 1 0 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.28 OQS02621.1 - 6.9e-23 80.6 0.1 1.1e-20 73.5 0.0 2.8 2 0 0 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain Jiv90 PF14901.6 OQS02621.1 - 0.00037 20.6 0.1 0.00092 19.3 0.1 1.6 1 0 0 1 1 1 1 Cleavage inducing molecular chaperone VASt PF16016.5 OQS02622.1 - 1.6e-25 90.3 0.6 2.5e-25 89.7 0.6 1.3 1 0 0 1 1 1 1 VAD1 Analog of StAR-related lipid transfer domain DUF4460 PF14687.6 OQS02622.1 - 1.3e-19 70.3 0.0 2.6e-19 69.3 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4460) FYVE PF01363.21 OQS02622.1 - 3.3e-10 39.9 11.7 6.6e-10 39.0 11.7 1.5 1 0 0 1 1 1 1 FYVE zinc finger GRAM PF02893.20 OQS02622.1 - 7.5e-06 25.8 0.3 3.2e-05 23.8 0.2 2.0 2 0 0 2 2 2 1 GRAM domain CR6_interact PF10147.9 OQS02622.1 - 0.69 9.6 4.1 0.24 11.1 0.3 2.2 2 0 0 2 2 2 0 Growth arrest and DNA-damage-inducible proteins-interacting protein 1 FYVE_2 PF02318.16 OQS02622.1 - 4.4 7.5 11.3 1.3 9.3 7.0 2.2 2 0 0 2 2 2 0 FYVE-type zinc finger zf-AN1 PF01428.16 OQS02624.1 - 1.3e-10 41.2 6.6 2.2e-10 40.5 6.6 1.3 1 0 0 1 1 1 1 AN1-like Zinc finger UPF0547 PF10571.9 OQS02624.1 - 0.16 12.1 3.4 0.31 11.1 3.4 1.5 1 0 0 1 1 1 0 Uncharacterised protein family UPF0547 PDEase_I PF00233.19 OQS02625.1 - 1.1e-50 172.6 1.9 1.5e-50 172.2 1.9 1.2 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase Beach PF02138.18 OQS02626.1 - 1.6e-115 385.3 0.9 3.9e-115 384.0 0.1 2.1 2 0 0 2 2 2 1 Beige/BEACH domain Vps53_N PF04100.12 OQS02626.1 - 7.4e-68 229.2 1.4 1.4e-67 228.4 1.4 1.4 1 0 0 1 1 1 1 Vps53-like, N-terminal PH_BEACH PF14844.6 OQS02626.1 - 7.3e-13 48.5 0.0 1.7e-12 47.3 0.0 1.7 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH WD40 PF00400.32 OQS02626.1 - 1.5e-06 28.8 5.1 0.27 12.2 0.2 4.3 3 0 0 3 3 3 3 WD domain, G-beta repeat Laminin_G_3 PF13385.6 OQS02626.1 - 1.9e-05 24.9 0.0 5.7e-05 23.3 0.0 1.8 2 0 0 2 2 2 1 Concanavalin A-like lectin/glucanases superfamily zf-C3HC4_3 PF13920.6 OQS02626.1 - 2e-05 24.4 7.2 2e-05 24.4 7.2 1.9 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 OQS02626.1 - 0.0015 18.4 8.0 0.0058 16.5 8.0 2.1 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OQS02626.1 - 0.0068 16.4 9.8 0.0065 16.5 6.9 2.4 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_2 PF13639.6 OQS02626.1 - 0.0078 16.5 7.3 0.025 14.9 7.3 2.0 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 OQS02626.1 - 0.027 14.4 8.2 0.088 12.8 8.2 2.0 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_4 PF15227.6 OQS02626.1 - 0.22 11.7 8.0 0.76 10.0 8.0 2.0 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_10 PF16685.5 OQS02626.1 - 0.28 11.4 5.0 0.72 10.0 5.0 1.7 1 0 0 1 1 1 0 zinc RING finger of MSL2 Prok-RING_4 PF14447.6 OQS02626.1 - 0.43 10.5 8.3 1.2 9.0 8.3 1.8 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 OQS02626.1 - 3.3 7.6 12.2 1.4 8.8 8.2 2.5 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Ank_2 PF12796.7 OQS02627.1 - 3.9e-34 117.1 6.8 3.5e-13 49.9 2.3 3.8 1 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQS02627.1 - 7.6e-30 102.9 6.6 2.6e-09 37.4 0.2 5.1 1 1 3 5 5 5 5 Ankyrin repeats (many copies) Ank PF00023.30 OQS02627.1 - 6.2e-29 99.2 7.9 8.7e-07 29.1 0.1 7.0 7 0 0 7 7 7 6 Ankyrin repeat Ank_3 PF13606.6 OQS02627.1 - 7.2e-24 81.3 2.7 0.00024 21.3 0.0 6.8 7 0 0 7 7 7 5 Ankyrin repeat Ank_5 PF13857.6 OQS02627.1 - 4.4e-21 74.7 6.4 2.1e-08 34.3 0.1 4.5 2 2 2 4 4 4 4 Ankyrin repeats (many copies) TctC PF03401.14 OQS02627.1 - 0.086 11.9 0.2 1.2 8.1 0.0 2.1 2 0 0 2 2 2 0 Tripartite tricarboxylate transporter family receptor IQ PF00612.27 OQS02628.1 - 4e-06 26.1 8.6 4.7e-05 22.8 0.2 3.2 3 0 0 3 3 3 2 IQ calmodulin-binding motif Sec1 PF00995.23 OQS02628.1 - 0.0065 15.8 0.6 0.011 14.9 0.6 1.3 1 0 0 1 1 1 1 Sec1 family Ribophorin_I PF04597.14 OQS02629.1 - 3.7e-127 425.2 2.4 4.7e-127 424.8 2.4 1.1 1 0 0 1 1 1 1 Ribophorin I PALP PF00291.25 OQS02629.1 - 1.6e-76 257.5 4.7 2.5e-76 256.9 4.7 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Thr_dehydrat_C PF00585.18 OQS02629.1 - 1.6e-34 117.5 0.0 1.6e-20 72.6 0.0 2.4 2 0 0 2 2 2 2 C-terminal regulatory domain of Threonine dehydratase NACHT PF05729.12 OQS02630.1 - 0.00044 20.2 0.0 0.00087 19.2 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 OQS02630.1 - 0.0036 17.7 0.0 0.0089 16.4 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 OQS02630.1 - 0.0063 16.8 0.0 0.022 15.0 0.0 1.9 1 0 0 1 1 1 1 AAA domain NB-ARC PF00931.22 OQS02630.1 - 0.0071 15.6 0.0 0.017 14.3 0.0 1.5 1 0 0 1 1 1 1 NB-ARC domain AAA_19 PF13245.6 OQS02630.1 - 0.012 15.9 2.2 0.023 15.0 0.0 2.4 2 1 0 2 2 2 0 AAA domain T2SSE PF00437.20 OQS02630.1 - 0.013 14.5 0.0 0.027 13.5 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein TryThrA_C PF12319.8 OQS02630.1 - 0.019 14.5 0.0 0.12 11.9 0.3 2.1 2 0 0 2 2 2 0 Tryptophan-Threonine-rich plasmodium antigen C terminal ABC_tran PF00005.27 OQS02630.1 - 0.035 14.6 2.2 0.047 14.2 0.0 2.3 3 0 0 3 3 3 0 ABC transporter DUF4715 PF15835.5 OQS02630.1 - 0.05 13.7 0.1 0.81 9.8 0.0 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4715) AAA_7 PF12775.7 OQS02630.1 - 0.1 12.1 0.9 0.21 11.1 0.0 1.9 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_30 PF13604.6 OQS02630.1 - 0.11 12.3 0.0 0.21 11.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain MCD_N PF17408.2 OQS02630.1 - 0.16 12.1 0.3 0.7 10.1 0.1 2.3 1 1 0 1 1 1 0 Malonyl-CoA decarboxylase N-terminal domain AAA PF00004.29 OQS02630.1 - 0.18 12.2 0.7 8.2 6.9 0.0 2.8 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) DUF1664 PF07889.12 OQS02630.1 - 0.65 10.0 4.1 12 6.0 0.9 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) GlcNAc PF11397.8 OQS02631.1 - 1.5e-52 179.2 1.2 6.5e-47 160.7 0.4 2.1 1 1 1 2 2 2 2 Glycosyltransferase (GlcNAc) SAT PF16073.5 OQS02632.1 - 0.045 13.5 0.0 0.072 12.8 0.0 1.3 1 0 0 1 1 1 0 Starter unit:ACP transacylase in aflatoxin biosynthesis Glycos_transf_1 PF00534.20 OQS02633.1 - 5.6e-21 74.8 0.0 1.6e-20 73.3 0.0 1.7 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 OQS02633.1 - 5.1e-18 65.8 0.0 9.6e-18 64.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 OQS02633.1 - 5.1e-08 33.1 0.0 1.8e-07 31.3 0.0 1.8 2 0 0 2 2 2 1 Glycosyltransferase Family 4 Glyco_trans_1_2 PF13524.6 OQS02633.1 - 0.011 16.1 0.0 0.021 15.2 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 OQS02633.1 - 0.053 14.0 0.0 0.099 13.1 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase 4-like domain Pkinase PF00069.25 OQS02634.1 - 8.2e-65 218.8 0.0 1.3e-64 218.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain cNMP_binding PF00027.29 OQS02634.1 - 4.5e-59 196.5 0.3 3.6e-20 71.8 0.1 3.4 3 0 0 3 3 3 3 Cyclic nucleotide-binding domain Pkinase_Tyr PF07714.17 OQS02634.1 - 2.4e-28 99.1 0.0 1.1e-27 97.0 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.23 OQS02634.1 - 0.0079 16.1 0.1 0.078 12.9 0.0 2.5 3 0 0 3 3 3 1 Phosphotransferase enzyme family Kinase-like PF14531.6 OQS02634.1 - 0.023 14.0 0.1 0.092 12.0 0.0 2.0 2 1 0 2 2 2 0 Kinase-like COG2 PF06148.11 OQS02635.1 - 0.24 11.5 2.8 0.34 11.0 2.8 1.3 1 0 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 HECT PF00632.25 OQS02636.1 - 2.1e-57 195.0 0.1 4.5e-57 193.9 0.1 1.5 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) MIB_HERC2 PF06701.13 OQS02636.1 - 2e-15 56.8 9.0 2.6e-15 56.4 0.3 3.0 3 0 0 3 3 3 2 Mib_herc2 SPRY PF00622.28 OQS02636.1 - 3.3e-13 49.8 0.5 4.1e-10 39.8 0.0 3.4 3 0 0 3 3 3 2 SPRY domain Laminin_G_3 PF13385.6 OQS02636.1 - 3.7e-08 33.7 0.0 1.1e-05 25.6 0.0 3.0 2 0 0 2 2 2 2 Concanavalin A-like lectin/glucanases superfamily Choline_transpo PF04515.12 OQS02637.1 - 9.8e-73 245.2 26.4 1.9e-72 244.2 26.4 1.5 1 0 0 1 1 1 1 Plasma-membrane choline transporter WD40 PF00400.32 OQS02637.1 - 2.1e-10 41.0 8.3 6.6e-06 26.8 0.5 6.7 6 1 0 6 6 6 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OQS02637.1 - 3.2e-09 37.0 1.6 0.0033 17.7 0.0 5.8 3 2 2 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain TPR_12 PF13424.6 OQS02637.1 - 0.0008 19.7 1.6 2 8.8 0.0 3.9 2 1 1 3 3 3 2 Tetratricopeptide repeat Clathrin PF00637.20 OQS02637.1 - 0.0044 16.9 3.3 0.31 10.9 0.8 3.4 1 1 2 3 3 3 1 Region in Clathrin and VPS Coatomer_WDAD PF04053.14 OQS02637.1 - 0.031 13.3 8.6 0.045 12.8 0.4 4.1 4 1 1 5 5 5 0 Coatomer WD associated region ANAPC3 PF12895.7 OQS02637.1 - 1 9.7 7.0 8.2 6.7 0.2 3.6 3 1 1 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 PIP5K PF01504.18 OQS02638.1 - 8.1e-38 130.2 1.1 9e-28 97.3 0.2 2.3 1 1 1 2 2 2 2 Phosphatidylinositol-4-phosphate 5-Kinase Cpn60_TCP1 PF00118.24 OQS02638.1 - 1.7e-27 96.2 0.2 4.8e-27 94.8 0.2 1.6 1 1 0 1 1 1 1 TCP-1/cpn60 chaperonin family FYVE PF01363.21 OQS02638.1 - 7.2e-14 51.7 18.4 7.2e-14 51.7 18.4 2.0 2 0 0 2 2 2 1 FYVE zinc finger DUF3798 PF12683.7 OQS02638.1 - 0.06 12.8 0.0 0.14 11.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3798) Minor_capsid_3 PF12691.7 OQS02638.1 - 0.13 12.7 0.0 0.29 11.5 0.0 1.6 1 0 0 1 1 1 0 Minor capsid protein from bacteriophage Pkinase_Tyr PF07714.17 OQS02639.1 - 1.3e-49 168.8 0.0 1.6e-49 168.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OQS02639.1 - 6.8e-45 153.5 0.0 9.7e-45 153.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain FeoB_associated PF12669.7 OQS02639.1 - 0.018 15.4 3.1 0.036 14.5 3.1 1.5 1 0 0 1 1 1 0 FeoB-associated Cys-rich membrane protein EphA2_TM PF14575.6 OQS02639.1 - 0.046 14.6 0.0 0.08 13.8 0.0 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain GRA6 PF05084.13 OQS02639.1 - 0.073 13.0 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 Granule antigen protein (GRA6) DUF1752 PF08550.10 OQS02639.1 - 0.074 12.9 0.1 0.19 11.6 0.1 1.8 1 0 0 1 1 1 0 Fungal protein of unknown function (DUF1752) APH PF01636.23 OQS02639.1 - 0.11 12.4 0.0 0.26 11.2 0.0 1.6 1 1 1 2 2 2 0 Phosphotransferase enzyme family DUF2749 PF10907.8 OQS02639.1 - 0.14 12.3 0.1 0.31 11.2 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2749) DUF3139 PF11337.8 OQS02639.1 - 0.15 12.7 0.0 0.28 11.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3139) PRK PF00485.18 OQS02641.1 - 8.9e-38 130.0 0.7 2.9e-37 128.3 0.0 2.3 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family AAA_18 PF13238.6 OQS02641.1 - 0.00024 21.7 0.0 0.0011 19.6 0.0 2.2 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 OQS02641.1 - 0.0018 18.4 0.1 0.015 15.5 0.0 2.7 2 0 0 2 2 2 1 AAA domain NADH_B2 PF14813.6 OQS02641.1 - 0.0044 16.8 0.0 3.3 7.6 0.0 3.6 4 0 0 4 4 4 1 NADH dehydrogenase 1 beta subcomplex subunit 2 betaPIX_CC PF16523.5 OQS02641.1 - 0.0066 16.3 9.9 4.9 7.0 0.1 5.6 5 0 0 5 5 5 2 betaPIX coiled coil T2SSE PF00437.20 OQS02641.1 - 0.0076 15.3 0.0 0.019 14.1 0.0 1.6 1 0 0 1 1 1 1 Type II/IV secretion system protein Anticodon_1 PF08264.13 OQS02641.1 - 0.014 15.4 3.5 4 7.4 0.0 4.5 5 0 0 5 5 5 0 Anticodon-binding domain of tRNA ABC_tran PF00005.27 OQS02641.1 - 0.033 14.7 0.0 0.19 12.3 0.0 2.3 1 0 0 1 1 1 0 ABC transporter NB-ARC PF00931.22 OQS02641.1 - 0.1 11.8 0.2 0.53 9.4 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain RNA_helicase PF00910.22 OQS02641.1 - 0.13 12.7 0.3 1.4 9.4 0.0 2.7 2 0 0 2 2 2 0 RNA helicase DUF2771 PF10969.8 OQS02641.1 - 0.16 12.0 1.0 23 5.0 0.0 3.6 4 0 0 4 4 4 0 Protein of unknown function (DUF2771) AAA_22 PF13401.6 OQS02641.1 - 0.47 10.7 3.0 2 8.7 0.0 3.4 3 0 0 3 3 3 0 AAA domain DUF87 PF01935.17 OQS02641.1 - 1.1 9.3 6.2 0.54 10.3 0.2 3.0 3 0 0 3 3 3 0 Helicase HerA, central domain Myb_DNA-bind_6 PF13921.6 OQS02643.1 - 0.00099 19.3 0.1 0.0024 18.1 0.1 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain SLIDE PF09111.10 OQS02643.1 - 0.011 15.8 0.0 0.011 15.8 0.0 2.1 3 0 0 3 3 3 0 SLIDE Myb_DNA-bind_3 PF12776.7 OQS02643.1 - 0.15 13.0 1.3 0.44 11.6 0.0 2.1 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain Radical_SAM PF04055.21 OQS02644.1 - 1.6e-11 44.9 0.0 5.2e-11 43.2 0.0 1.9 1 1 0 1 1 1 1 Radical SAM superfamily LIAS_N PF16881.5 OQS02644.1 - 2.1e-10 41.0 0.0 4.7e-10 39.8 0.0 1.7 1 0 0 1 1 1 1 N-terminal domain of lipoyl synthase of Radical_SAM family Cytochrom_C1 PF02167.15 OQS02646.1 - 1.6e-97 325.5 0.0 1.9e-97 325.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome C1 family Cytochrome_CBB3 PF13442.6 OQS02646.1 - 0.00065 20.0 0.1 0.0021 18.4 0.0 2.0 2 0 0 2 2 2 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C PF00034.21 OQS02646.1 - 0.028 15.6 0.2 0.081 14.1 0.2 1.9 1 1 0 1 1 1 0 Cytochrome c RNase_PH PF01138.21 OQS02647.1 - 7e-26 91.3 0.0 9.8e-26 90.8 0.0 1.2 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 OQS02647.1 - 0.00033 20.6 0.0 0.00073 19.5 0.0 1.6 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 Dynamin_N PF00350.23 OQS02648.1 - 2.2e-18 66.9 0.0 4.3e-18 65.9 0.0 1.5 1 0 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.23 OQS02648.1 - 1.3e-05 25.2 0.0 9e-05 22.5 0.0 2.4 2 1 0 2 2 2 1 50S ribosome-binding GTPase AAA_16 PF13191.6 OQS02648.1 - 0.00061 20.2 0.0 0.0019 18.6 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain FeoB_N PF02421.18 OQS02648.1 - 0.012 15.2 0.1 5.8 6.4 0.0 2.6 2 0 0 2 2 2 0 Ferrous iron transport protein B ABC_tran PF00005.27 OQS02648.1 - 0.03 14.8 0.0 0.15 12.6 0.0 2.1 2 0 0 2 2 2 0 ABC transporter Dynamin_M PF01031.20 OQS02648.1 - 0.043 13.0 0.6 0.11 11.7 0.6 1.7 1 0 0 1 1 1 0 Dynamin central region AAA_23 PF13476.6 OQS02648.1 - 0.066 13.7 0.0 0.19 12.2 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 OQS02648.1 - 0.13 12.8 0.0 0.57 10.7 0.0 2.2 1 0 0 1 1 1 0 AAA domain Cas9_Topo PF17894.1 OQS02648.1 - 0.75 9.9 4.0 0.9 9.6 0.5 2.4 2 0 0 2 2 2 0 Topo homolgy domain in CRISPR-associated endonuclease Cas9 Arf PF00025.21 OQS02649.1 - 1.2e-45 155.1 0.1 1.3e-45 155.0 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 OQS02649.1 - 1.2e-12 48.1 0.0 1.8e-12 47.5 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 OQS02649.1 - 3.1e-11 43.1 0.0 4e-11 42.8 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.20 OQS02649.1 - 2.9e-10 39.8 0.1 1.4e-06 27.7 0.0 2.4 1 1 1 2 2 2 2 G-protein alpha subunit MMR_HSR1 PF01926.23 OQS02649.1 - 2.1e-09 37.5 0.0 3.4e-09 36.8 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 OQS02649.1 - 9.4e-08 31.7 0.0 1.2e-07 31.3 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 OQS02649.1 - 1.3e-06 28.0 0.0 1.6e-06 27.7 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 OQS02649.1 - 1.8e-06 27.6 0.0 4.4e-05 23.1 0.0 2.2 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain cobW PF02492.19 OQS02649.1 - 0.00013 21.6 0.0 0.038 13.6 0.0 2.1 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain FeoB_N PF02421.18 OQS02649.1 - 0.0042 16.6 0.8 0.11 12.0 0.1 2.2 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.23 OQS02649.1 - 0.017 15.2 0.2 4.2 7.4 0.1 2.1 1 1 1 2 2 2 0 Dynamin family RsgA_GTPase PF03193.16 OQS02649.1 - 0.04 13.8 0.1 8.5 6.3 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase NTPase_1 PF03266.15 OQS02649.1 - 0.1 12.5 0.0 0.13 12.2 0.0 1.1 1 0 0 1 1 1 0 NTPase ATP-synt_D PF01813.17 OQS02650.1 - 3e-61 206.7 4.3 3.7e-61 206.4 4.3 1.1 1 0 0 1 1 1 1 ATP synthase subunit D DUF573 PF04504.14 OQS02650.1 - 0.018 15.7 1.7 0.14 12.8 0.4 2.5 2 1 1 3 3 3 0 Protein of unknown function, DUF573 ApoLp-III PF07464.11 OQS02650.1 - 0.036 14.1 5.2 0.19 11.8 1.5 2.2 2 0 0 2 2 2 0 Apolipophorin-III precursor (apoLp-III) DUF1451 PF07295.11 OQS02650.1 - 0.27 11.2 2.3 0.37 10.8 0.6 2.0 2 1 0 2 2 2 0 Zinc-ribbon containing domain FliN_N PF16973.5 OQS02650.1 - 0.34 10.8 2.8 0.87 9.5 2.8 1.7 1 0 0 1 1 1 0 Flagellar motor switch protein FliN N-terminal Peptidase_C1 PF00112.23 OQS02651.1 - 2.5e-42 145.5 5.4 3e-42 145.2 5.4 1.0 1 0 0 1 1 1 1 Papain family cysteine protease DUF1839 PF08893.10 OQS02651.1 - 0.045 12.9 0.0 0.14 11.3 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1839) Peptidase_C1_2 PF03051.15 OQS02651.1 - 0.1 11.4 0.1 0.14 10.9 0.1 1.1 1 0 0 1 1 1 0 Peptidase C1-like family Rogdi_lz PF10259.9 OQS02652.1 - 8.3e-11 41.8 0.4 1.2e-10 41.3 0.4 1.3 1 0 0 1 1 1 1 Rogdi leucine zipper containing protein Ricin_B_lectin PF00652.22 OQS02653.1 - 4.2e-23 82.0 17.5 8e-13 48.8 3.6 2.4 2 0 0 2 2 2 2 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.6 OQS02653.1 - 8.9e-05 23.1 21.9 0.018 15.7 6.0 4.6 1 1 3 4 4 4 4 Ricin-type beta-trefoil lectin domain-like HTH_24 PF13412.6 OQS02653.1 - 0.11 12.1 0.0 0.31 10.7 0.0 1.7 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding zf-CCCH PF00642.24 OQS02654.1 - 1e-12 47.6 12.3 3.3e-06 26.9 2.4 2.5 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 OQS02654.1 - 6.5e-12 45.0 16.5 3e-07 30.1 2.8 2.7 3 0 0 3 3 2 2 CCCH-type zinc finger zf_CCCH_4 PF18345.1 OQS02654.1 - 1e-09 38.1 22.8 1.5e-05 24.9 4.7 2.7 3 0 0 3 3 2 2 Zinc finger domain Torus PF16131.5 OQS02654.1 - 8e-06 26.5 12.8 0.0025 18.5 4.8 2.6 1 1 1 2 2 2 2 Torus domain zf-C2H2_jaz PF12171.8 OQS02654.1 - 1e-05 25.7 2.2 1e-05 25.7 2.2 2.7 2 1 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 OQS02654.1 - 3.7e-05 23.9 2.7 0.00013 22.2 0.8 2.6 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 OQS02654.1 - 0.0013 19.1 5.5 0.041 14.2 5.2 2.3 1 1 1 2 2 2 1 C2H2 type zinc-finger (2 copies) zf-CCCH_3 PF15663.5 OQS02654.1 - 0.002 18.3 4.1 0.0054 16.9 4.1 1.8 1 0 0 1 1 1 1 Zinc-finger containing family zf-C2H2 PF00096.26 OQS02654.1 - 0.0027 18.1 3.7 0.027 14.9 0.4 3.0 2 1 1 3 3 3 1 Zinc finger, C2H2 type zf-CCCH_2 PF14608.6 OQS02654.1 - 0.0097 16.3 11.2 0.65 10.6 2.6 2.5 2 0 0 2 2 2 2 RNA-binding, Nab2-type zinc finger FlxA PF14282.6 OQS02654.1 - 0.025 14.5 2.7 0.025 14.5 2.7 1.7 2 0 0 2 2 1 0 FlxA-like protein zf-C2H2_6 PF13912.6 OQS02654.1 - 0.045 13.8 1.2 0.13 12.3 1.2 1.9 1 0 0 1 1 1 0 C2H2-type zinc finger DUF1959 PF09218.10 OQS02654.1 - 0.045 13.9 0.4 0.074 13.2 0.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1959) Ig_J_chain PF15097.6 OQS02654.1 - 0.11 12.3 1.3 0.54 10.1 1.1 2.1 1 1 1 2 2 2 0 Immunoglobulin J chain zf-C2H2_4 PF13894.6 OQS02654.1 - 0.19 12.7 0.2 0.19 12.7 0.2 3.2 3 0 0 3 3 2 0 C2H2-type zinc finger LIN37 PF15306.6 OQS02654.1 - 6.3 7.0 11.9 87 3.3 11.6 2.2 1 1 0 1 1 1 0 LIN37 Mito_carr PF00153.27 OQS02655.1 - 1.3e-131 428.9 20.5 8.9e-24 83.2 0.1 6.4 6 0 0 6 6 6 6 Mitochondrial carrier protein Glyco_hydro_47 PF01532.20 OQS02655.1 - 2e-130 435.8 2.2 3.1e-130 435.2 2.2 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 DUF5060 PF16586.5 OQS02655.1 - 0.062 13.7 0.4 0.33 11.4 0.0 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF5060) AlaE PF06610.13 OQS02655.1 - 0.098 12.7 0.3 0.93 9.5 0.1 2.5 2 0 0 2 2 2 0 L-alanine exporter Act-Frag_cataly PF09192.10 OQS02656.1 - 0.029 13.8 0.0 0.052 12.9 0.0 1.4 1 0 0 1 1 1 0 Actin-fragmin kinase, catalytic Serinc PF03348.15 OQS02657.1 - 9.9e-63 212.5 23.9 3.7e-62 210.7 23.9 1.7 1 1 0 1 1 1 1 Serine incorporator (Serinc) Pkinase PF00069.25 OQS02658.1 - 4.2e-74 249.2 0.0 7.1e-74 248.5 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQS02658.1 - 5.9e-33 114.3 0.0 9.2e-33 113.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 OQS02658.1 - 0.001 18.5 0.1 0.0019 17.6 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 OQS02658.1 - 0.0048 16.5 0.3 0.011 15.3 0.3 1.6 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 OQS02658.1 - 0.023 14.7 0.1 0.15 12.0 0.1 1.9 1 1 1 2 2 2 0 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.9 OQS02658.1 - 0.054 13.0 0.0 0.15 11.5 0.0 1.7 1 1 0 1 1 1 0 PhoP regulatory network protein YrbL FTA2 PF13095.6 OQS02658.1 - 0.058 13.0 1.1 1.7 8.2 0.0 2.7 2 1 0 3 3 3 0 Kinetochore Sim4 complex subunit FTA2 Pkinase_fungal PF17667.1 OQS02658.1 - 0.49 9.1 6.9 0.62 8.8 0.0 2.5 2 0 0 2 2 2 0 Fungal protein kinase Vps8 PF12816.7 OQS02659.1 - 3.8e-38 131.0 3.9 1.7e-36 125.6 1.2 3.0 2 0 0 2 2 2 2 Golgi CORVET complex core vacuolar protein 8 Clathrin PF00637.20 OQS02659.1 - 4.3e-12 46.1 3.1 6.4e-06 26.1 0.0 4.3 3 1 0 3 3 3 3 Region in Clathrin and VPS WWE PF02825.20 OQS02659.1 - 3.5e-05 24.3 0.8 0.16 12.6 0.0 3.8 2 1 1 3 3 3 2 WWE domain WD40 PF00400.32 OQS02659.1 - 0.0049 17.7 0.9 0.018 15.9 0.2 2.5 2 0 0 2 2 2 1 WD domain, G-beta repeat Phosducin PF02114.16 OQS02660.1 - 1.7e-18 66.6 2.9 1.6e-16 60.0 2.9 2.0 1 1 0 1 1 1 1 Phosducin Abi_2 PF07751.11 OQS02660.1 - 0.0095 16.2 0.1 0.014 15.6 0.1 1.1 1 0 0 1 1 1 1 Abi-like protein MRC1 PF09444.10 OQS02660.1 - 0.033 14.7 0.1 0.033 14.7 0.1 1.6 2 0 0 2 2 2 0 MRC1-like domain Rox3 PF08633.10 OQS02660.1 - 0.13 12.5 1.8 0.19 12.0 1.8 1.2 1 0 0 1 1 1 0 Rox3 mediator complex subunit Peptidase_C1 PF00112.23 OQS02661.1 - 2e-30 106.5 12.5 6.5e-29 101.6 12.5 2.1 1 1 0 1 1 1 1 Papain family cysteine protease Glyco_hydro_76 PF03663.14 OQS02661.1 - 0.033 13.7 0.0 0.046 13.2 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 76 GAF PF01590.26 OQS02661.1 - 0.082 13.5 0.1 0.25 12.0 0.0 1.6 1 1 1 2 2 2 0 GAF domain Peptidase_C2 PF00648.21 OQS02662.1 - 3.9e-12 45.8 0.0 5.7e-12 45.3 0.0 1.2 1 0 0 1 1 1 1 Calpain family cysteine protease EF-hand_7 PF13499.6 OQS02662.1 - 0.00023 21.6 0.7 0.00056 20.3 0.7 1.6 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 OQS02662.1 - 0.00053 19.3 1.3 0.00053 19.3 1.3 2.0 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.6 OQS02662.1 - 0.003 17.4 2.2 0.0097 15.8 2.2 1.9 1 0 0 1 1 1 1 EF-hand domain EF-hand_5 PF13202.6 OQS02662.1 - 0.0059 16.0 2.6 0.0059 16.0 2.6 2.3 3 0 0 3 3 3 1 EF hand EF-hand_8 PF13833.6 OQS02662.1 - 0.13 12.1 1.2 0.75 9.7 0.8 2.4 2 1 1 3 3 3 0 EF-hand domain pair MORN PF02493.20 OQS02663.1 - 2.1e-14 52.4 19.5 3.7e-06 26.5 3.0 4.3 4 1 0 4 4 4 3 MORN repeat EFTUD2 PF16004.5 OQS02663.1 - 0.064 13.8 0.1 0.1 13.2 0.1 1.3 1 0 0 1 1 1 0 116 kDa U5 small nuclear ribonucleoprotein component N-terminus Trypsin PF00089.26 OQS02665.1 - 0.012 15.4 0.4 0.021 14.6 0.4 1.3 1 0 0 1 1 1 0 Trypsin Trypsin_2 PF13365.6 OQS02665.1 - 0.018 15.9 0.9 0.051 14.5 0.8 1.6 1 1 0 1 1 1 0 Trypsin-like peptidase domain Peptidase_S32 PF05579.13 OQS02665.1 - 0.13 11.4 0.5 0.23 10.6 0.5 1.3 1 0 0 1 1 1 0 Equine arteritis virus serine endopeptidase S32 YiiD_C PF09500.10 OQS02665.1 - 0.16 11.8 0.1 0.67 9.8 0.1 1.9 2 1 1 3 3 3 0 Putative thioesterase (yiiD_Cterm) Peptidase_S7 PF00949.21 OQS02665.1 - 0.25 11.1 2.6 0.68 9.7 0.3 2.3 2 0 0 2 2 2 0 Peptidase S7, Flavivirus NS3 serine protease Peptidase_S29 PF02907.15 OQS02665.1 - 0.27 11.0 2.4 0.3 10.8 0.9 1.8 2 0 0 2 2 2 0 Hepatitis C virus NS3 protease Peptidase_C3 PF00548.20 OQS02665.1 - 0.29 11.0 0.8 0.65 9.9 0.8 1.6 1 0 0 1 1 1 0 3C cysteine protease (picornain 3C) VHS PF00790.19 OQS02667.1 - 9.9e-13 48.1 0.0 1.6e-12 47.4 0.0 1.3 1 0 0 1 1 1 1 VHS domain GAT PF03127.14 OQS02667.1 - 0.0039 17.5 0.7 0.0039 17.5 0.7 2.4 3 1 0 3 3 3 1 GAT domain Apolipoprotein PF01442.18 OQS02667.1 - 0.057 13.3 0.2 0.11 12.4 0.2 1.4 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain ABC_tran_CTD PF16326.5 OQS02667.1 - 0.11 12.7 0.2 0.27 11.5 0.2 1.6 1 0 0 1 1 1 0 ABC transporter C-terminal domain EzrA PF06160.12 OQS02667.1 - 0.12 10.6 0.0 0.15 10.2 0.0 1.3 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA JAKMIP_CC3 PF16034.5 OQS02667.1 - 0.19 11.6 1.2 0.28 11.1 0.6 1.6 1 1 1 2 2 2 0 JAKMIP CC3 domain His_Phos_1 PF00300.22 OQS02668.1 - 7.5e-34 117.1 0.1 8.3e-27 94.1 0.1 2.1 1 1 1 2 2 2 2 Histidine phosphatase superfamily (branch 1) Tyr_Deacylase PF02580.16 OQS02669.1 - 9.4e-46 155.9 0.0 1.7e-45 155.1 0.0 1.4 1 0 0 1 1 1 1 D-Tyr-tRNA(Tyr) deacylase Acid_phosphat_B PF03767.14 OQS02669.1 - 1.3e-22 80.5 0.0 2.4e-22 79.7 0.0 1.4 1 0 0 1 1 1 1 HAD superfamily, subfamily IIIB (Acid phosphatase) DUF2608 PF11019.8 OQS02669.1 - 0.055 12.9 0.0 2.3 7.7 0.0 2.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2608) BTB_2 PF02214.22 OQS02670.1 - 6.2e-08 32.9 0.1 1.5e-07 31.6 0.0 1.6 2 0 0 2 2 2 1 BTB/POZ domain Prefoldin_2 PF01920.20 OQS02670.1 - 0.012 15.6 4.7 0.016 15.1 1.6 2.3 1 1 1 2 2 2 0 Prefoldin subunit ROK PF00480.20 OQS02671.1 - 1.6e-55 188.7 0.0 2.1e-55 188.3 0.0 1.1 1 0 0 1 1 1 1 ROK family CBM_1 PF00734.18 OQS02672.1 - 0.0042 17.0 2.0 0.0084 16.1 2.0 1.5 1 0 0 1 1 1 1 Fungal cellulose binding domain dsrm PF00035.26 OQS02673.1 - 3.4e-19 69.3 4.3 7.1e-10 39.5 0.0 3.5 3 1 0 3 3 3 2 Double-stranded RNA binding motif BSD PF03909.17 OQS02673.1 - 3.3e-08 33.4 0.1 8.5e-08 32.1 0.1 1.7 1 0 0 1 1 1 1 BSD domain WW PF00397.26 OQS02673.1 - 0.00055 20.0 0.0 0.0014 18.7 0.0 1.8 1 0 0 1 1 1 1 WW domain ApoLp-III PF07464.11 OQS02673.1 - 4 7.5 12.1 0.15 12.1 2.9 3.1 4 0 0 4 4 4 0 Apolipophorin-III precursor (apoLp-III) Med31 PF05669.12 OQS02674.1 - 9.2e-25 86.5 2.6 1.1e-24 86.3 2.6 1.0 1 0 0 1 1 1 1 SOH1 N_BRCA1_IG PF16158.5 OQS02675.1 - 9.4e-31 106.6 0.0 2.9e-30 105.0 0.0 1.9 1 0 0 1 1 1 1 Ig-like domain from next to BRCA1 gene PB1 PF00564.24 OQS02675.1 - 0.004 17.0 0.0 0.011 15.6 0.0 1.8 1 0 0 1 1 1 1 PB1 domain UBA PF00627.31 OQS02675.1 - 0.11 12.5 1.8 0.2 11.6 0.5 2.1 2 0 0 2 2 2 0 UBA/TS-N domain Glycos_transf_2 PF00535.26 OQS02676.1 - 1e-23 84.0 0.0 1.7e-23 83.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 OQS02676.1 - 2.9e-11 43.7 0.0 3.7e-11 43.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 OQS02676.1 - 3.4e-08 33.3 0.0 1.7e-07 31.0 0.0 1.9 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_tranf_2_4 PF13704.6 OQS02676.1 - 3.5e-06 27.4 0.0 7.4e-06 26.4 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 2 CoA_binding PF02629.19 OQS02676.1 - 0.0045 17.6 0.1 0.071 13.8 0.0 2.4 3 0 0 3 3 3 1 CoA binding domain PIF1 PF05970.14 OQS02677.1 - 3.5e-45 154.7 7.3 1e-42 146.7 7.3 3.3 1 1 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.6 OQS02677.1 - 6.1e-24 84.8 1.8 1e-23 84.1 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 OQS02677.1 - 3.1e-08 34.1 0.6 1.3e-07 32.0 0.0 2.4 2 1 0 2 2 2 1 AAA domain SF-assemblin PF06705.11 OQS02677.1 - 4.1e-06 26.3 24.1 9e-06 25.2 24.1 1.5 1 0 0 1 1 1 1 SF-assemblin/beta giardin AAA_22 PF13401.6 OQS02677.1 - 6e-06 26.6 4.1 2.2e-05 24.7 0.0 3.3 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.6 OQS02677.1 - 8.2e-05 23.0 0.1 8.2e-05 23.0 0.1 2.5 2 2 0 2 2 2 1 AAA ATPase domain PhoH PF02562.16 OQS02677.1 - 0.00021 20.8 0.0 0.0011 18.5 0.0 2.2 2 0 0 2 2 2 1 PhoH-like protein AAA_5 PF07728.14 OQS02677.1 - 0.00034 20.6 0.2 0.0014 18.6 0.0 2.2 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) Viral_helicase1 PF01443.18 OQS02677.1 - 0.0014 18.4 2.3 1.3 8.7 0.1 3.4 3 1 0 3 3 3 2 Viral (Superfamily 1) RNA helicase AAA_7 PF12775.7 OQS02677.1 - 0.0021 17.6 0.0 0.0077 15.8 0.0 1.9 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA PF00004.29 OQS02677.1 - 0.0027 18.1 2.6 0.012 16.1 0.0 2.7 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.17 OQS02677.1 - 0.015 15.0 0.9 0.16 11.7 0.9 2.5 1 1 0 1 1 1 0 IstB-like ATP binding protein AAA_14 PF13173.6 OQS02677.1 - 0.023 14.7 0.3 0.11 12.6 0.0 2.4 2 0 0 2 2 2 0 AAA domain Mg_chelatase PF01078.21 OQS02677.1 - 0.038 13.4 0.0 0.14 11.6 0.0 1.8 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI RsgA_GTPase PF03193.16 OQS02677.1 - 0.039 13.9 0.0 0.12 12.3 0.0 1.8 1 0 0 1 1 1 0 RsgA GTPase NACHT PF05729.12 OQS02677.1 - 0.049 13.5 0.2 0.16 11.8 0.2 2.0 1 1 0 1 1 1 0 NACHT domain RNA_helicase PF00910.22 OQS02677.1 - 0.062 13.7 0.1 1 9.8 0.0 2.7 2 0 0 2 2 2 0 RNA helicase UvrD_C_2 PF13538.6 OQS02677.1 - 0.089 12.6 0.0 0.22 11.4 0.0 1.7 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain DEAD PF00270.29 OQS02677.1 - 0.1 12.3 0.9 4.6 7.0 0.0 3.2 3 0 0 3 3 3 0 DEAD/DEAH box helicase TsaE PF02367.17 OQS02677.1 - 0.23 11.5 1.8 0.38 10.8 0.2 2.2 2 0 0 2 2 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ABC_tran PF00005.27 OQS02677.1 - 0.54 10.8 0.0 0.54 10.8 0.0 3.7 2 1 0 3 3 3 0 ABC transporter RGS PF00615.19 OQS02677.1 - 5.7 7.2 9.9 32 4.8 3.7 3.6 1 1 2 3 3 3 0 Regulator of G protein signaling domain TPH PF13868.6 OQS02678.1 - 3.6e-35 121.1 120.4 3.6e-35 121.1 120.4 2.7 2 1 1 3 3 3 1 Trichohyalin-plectin-homology domain Myb_DNA-binding PF00249.31 OQS02678.1 - 6.4e-08 32.7 0.1 1.7e-07 31.3 0.1 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain Ribosomal_L37e PF01907.19 OQS02679.1 - 1.3e-25 89.3 9.9 2.2e-25 88.5 9.9 1.4 1 0 0 1 1 1 1 Ribosomal protein L37e DUF2688 PF10892.8 OQS02679.1 - 0.018 14.5 4.0 0.14 11.7 3.4 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2688) DZR PF12773.7 OQS02679.1 - 0.025 14.6 1.3 0.039 14.0 1.3 1.3 1 0 0 1 1 1 0 Double zinc ribbon DUF1258 PF06869.12 OQS02679.1 - 0.08 12.4 1.2 0.11 12.0 1.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1258) zf-RING_10 PF16685.5 OQS02679.1 - 0.083 13.0 1.4 0.11 12.7 1.4 1.2 1 0 0 1 1 1 0 zinc RING finger of MSL2 HypA PF01155.19 OQS02679.1 - 0.13 12.3 1.5 0.18 11.8 1.5 1.2 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Ank_4 PF13637.6 OQS02680.1 - 1.2e-13 51.2 4.6 2.4e-07 31.2 0.2 2.8 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 OQS02680.1 - 1.2e-12 48.3 1.2 6.7e-06 26.6 0.6 2.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OQS02680.1 - 2e-08 34.3 0.4 0.00099 19.4 0.1 2.8 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQS02680.1 - 2.8e-08 33.4 0.2 0.023 15.2 0.0 3.9 4 0 0 4 4 4 2 Ankyrin repeat Ank PF00023.30 OQS02680.1 - 7.2e-08 32.6 2.2 0.027 14.9 0.0 3.7 4 0 0 4 4 4 2 Ankyrin repeat 2OG-FeII_Oxy_3 PF13640.6 OQS02680.1 - 0.00032 21.5 0.0 0.0006 20.7 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily PhyH PF05721.13 OQS02680.1 - 0.069 13.4 0.2 0.29 11.4 0.1 2.0 3 0 0 3 3 3 0 Phytanoyl-CoA dioxygenase (PhyH) DUF348 PF03990.14 OQS02680.1 - 0.099 12.4 0.0 0.21 11.3 0.0 1.5 1 0 0 1 1 1 0 G5-linked-Ubiquitin-like domain COQ7 PF03232.13 OQS02681.1 - 3.1e-11 43.3 0.0 3.8e-11 43.1 0.0 1.2 1 0 0 1 1 1 1 Ubiquinone biosynthesis protein COQ7 Nop52 PF05997.12 OQS02681.1 - 0.082 12.7 0.0 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 Nucleolar protein,Nop52 Glycos_transf_3 PF00591.21 OQS02682.1 - 1.7e-91 306.3 0.9 2e-91 306.1 0.2 1.4 2 0 0 2 2 2 1 Glycosyl transferase family, a/b domain Glycos_trans_3N PF02885.17 OQS02682.1 - 3.2e-17 62.1 0.8 7e-17 61.0 0.8 1.6 1 0 0 1 1 1 1 Glycosyl transferase family, helical bundle domain Sec34 PF04136.15 OQS02683.1 - 4.1e-18 65.7 8.7 2.2e-11 43.8 0.3 3.3 3 0 0 3 3 3 2 Sec34-like family BLOC1_2 PF10046.9 OQS02683.1 - 0.011 16.0 0.8 0.11 12.8 0.6 2.8 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Coat_F PF07875.12 OQS02683.1 - 0.35 11.1 4.1 1.5 9.1 0.2 3.4 2 0 0 2 2 2 0 Coat F domain Pkinase PF00069.25 OQS02684.1 - 1.2e-42 146.1 0.0 2e-42 145.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQS02684.1 - 1.6e-37 129.2 0.0 2.9e-37 128.4 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OQS02684.1 - 1.9e-05 23.6 0.0 2.9e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase LRR_8 PF13855.6 OQS02684.1 - 0.0037 17.0 2.2 0.02 14.7 2.1 2.2 1 1 0 1 1 1 1 Leucine rich repeat LRR_4 PF12799.7 OQS02684.1 - 0.0092 16.4 4.8 0.22 12.0 3.0 2.8 1 1 1 2 2 2 2 Leucine Rich repeats (2 copies) Kdo PF06293.14 OQS02684.1 - 0.037 13.4 0.0 0.062 12.6 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Cellulose_synt PF03552.14 OQS02685.1 - 2.1e-22 79.5 8.3 9.6e-12 44.2 0.9 4.0 3 1 1 4 4 4 3 Cellulose synthase Glyco_trans_2_3 PF13632.6 OQS02685.1 - 9.4e-14 51.8 2.6 1.9e-13 50.8 0.0 2.4 2 0 0 2 2 2 1 Glycosyl transferase family group 2 PH PF00169.29 OQS02685.1 - 2e-09 37.9 0.1 5.9e-09 36.4 0.1 1.8 1 0 0 1 1 1 1 PH domain Glyco_tranf_2_3 PF13641.6 OQS02685.1 - 4.7e-07 29.9 0.0 0.062 13.2 0.0 3.2 3 0 0 3 3 3 2 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 OQS02685.1 - 1.5e-05 24.9 0.0 0.24 11.2 0.0 3.5 3 0 0 3 3 3 2 Glycosyl transferase family 2 PH_8 PF15409.6 OQS02685.1 - 2.6e-05 24.4 0.2 0.00022 21.4 0.2 2.3 1 1 0 1 1 1 1 Pleckstrin homology domain zf-C6H2 PF15801.5 OQS02685.1 - 9.5e-05 22.6 3.5 9.5e-05 22.6 3.5 2.5 3 0 0 3 3 3 1 zf-MYND-like zinc finger, mRNA-binding Glyco_transf_21 PF13506.6 OQS02685.1 - 0.00016 21.2 0.0 0.0042 16.6 0.0 2.4 2 0 0 2 2 2 1 Glycosyl transferase family 21 Mcp5_PH PF12814.7 OQS02685.1 - 0.082 13.0 0.0 0.15 12.1 0.0 1.4 1 0 0 1 1 1 0 Meiotic cell cortex C-terminal pleckstrin homology Rubredoxin_2 PF18073.1 OQS02685.1 - 1.4 8.7 6.8 4 7.2 6.8 1.8 1 0 0 1 1 1 0 Rubredoxin metal binding domain Zn_ribbon_SprT PF17283.2 OQS02685.1 - 2.8 7.9 9.6 11 6.0 2.8 2.8 1 1 1 2 2 2 0 SprT-like zinc ribbon domain Acetyltransf_1 PF00583.25 OQS02686.1 - 1.8e-06 28.2 0.0 2e-05 24.8 0.0 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.7 OQS02686.1 - 2.6e-06 27.5 0.0 1.1e-05 25.5 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 OQS02686.1 - 2e-05 24.6 0.0 2.9e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 OQS02686.1 - 0.00021 21.2 0.0 0.00043 20.2 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.7 OQS02686.1 - 0.00071 20.0 0.0 0.0012 19.2 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 OQS02686.1 - 0.015 15.4 0.1 0.092 12.9 0.0 2.2 2 0 0 2 2 2 0 GCN5-related N-acetyl-transferase GPCR_chapero_1 PF11904.8 OQS02687.1 - 1e-31 110.6 0.5 1.7e-31 109.8 0.5 1.3 1 0 0 1 1 1 1 GPCR-chaperone Ank_2 PF12796.7 OQS02687.1 - 1.6e-06 28.6 0.0 3.4e-06 27.6 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 OQS02687.1 - 2.6e-05 24.5 0.1 0.0021 18.5 0.0 2.5 2 0 0 2 2 2 1 Ankyrin repeat Ank_5 PF13857.6 OQS02687.1 - 0.00011 22.5 0.0 0.31 11.4 0.0 3.1 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 OQS02687.1 - 0.00019 21.9 0.1 0.48 11.1 0.1 2.6 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQS02687.1 - 0.0049 17.3 0.0 0.048 14.2 0.0 2.4 2 0 0 2 2 2 1 Ankyrin repeat DHHC PF01529.20 OQS02688.1 - 8.5e-35 119.8 6.6 8.5e-35 119.8 6.6 2.1 2 0 0 2 2 2 1 DHHC palmitoyltransferase PIG-P PF08510.12 OQS02688.1 - 0.0072 16.2 0.1 0.0072 16.2 0.1 2.2 2 0 0 2 2 2 1 PIG-P FA_desaturase PF00487.24 OQS02688.1 - 0.044 13.6 6.0 0.5 10.1 1.4 2.2 2 0 0 2 2 2 0 Fatty acid desaturase SK_channel PF03530.14 OQS02688.1 - 0.67 10.0 3.8 0.21 11.6 0.5 1.8 2 0 0 2 2 2 0 Calcium-activated SK potassium channel Protoglobin PF11563.8 OQS02689.1 - 0.084 12.8 0.2 0.12 12.2 0.2 1.2 1 0 0 1 1 1 0 Protoglobin Takusan PF04822.13 OQS02689.1 - 0.088 12.7 2.5 2.6 8.0 0.3 2.4 2 0 0 2 2 2 0 Takusan Ank_2 PF12796.7 OQS02690.1 - 8.6e-33 112.8 0.0 2.7e-13 50.3 0.0 5.2 2 1 2 5 5 5 5 Ankyrin repeats (3 copies) TIR_2 PF13676.6 OQS02690.1 - 7.2e-26 91.1 0.2 5.7e-18 65.6 0.0 2.5 2 0 0 2 2 2 2 TIR domain Ank PF00023.30 OQS02690.1 - 1.7e-22 78.8 1.0 0.022 15.2 0.0 7.7 8 0 0 8 8 8 5 Ankyrin repeat Ank_3 PF13606.6 OQS02690.1 - 6.2e-22 75.3 1.8 0.0043 17.4 0.0 8.4 8 1 1 9 9 9 4 Ankyrin repeat Ank_5 PF13857.6 OQS02690.1 - 4.6e-20 71.4 3.8 1.8e-05 24.9 0.1 7.1 4 1 4 8 8 8 7 Ankyrin repeats (many copies) Ank_4 PF13637.6 OQS02690.1 - 2.3e-18 66.3 3.0 5.9e-07 29.9 0.0 7.0 4 2 4 8 8 8 6 Ankyrin repeats (many copies) TIR PF01582.20 OQS02690.1 - 3.4e-06 27.0 0.0 4.6e-05 23.3 0.0 2.3 2 0 0 2 2 2 1 TIR domain DUF1863 PF08937.11 OQS02690.1 - 0.078 13.3 0.0 0.21 11.9 0.0 1.8 1 1 0 1 1 1 0 MTH538 TIR-like domain (DUF1863) TGS PF02824.21 OQS02690.1 - 0.15 12.2 0.0 3.4 7.8 0.0 2.6 2 0 0 2 2 2 0 TGS domain EMP70 PF02990.16 OQS02690.1 - 0.43 9.2 6.9 0.78 8.3 6.9 1.4 1 0 0 1 1 1 0 Endomembrane protein 70 PhyH PF05721.13 OQS02691.1 - 3.8e-17 63.3 0.3 6.4e-17 62.5 0.3 1.6 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) 2OG-FeII_Oxy_3 PF13640.6 OQS02691.1 - 0.074 13.9 0.0 0.14 13.1 0.0 1.4 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily COX7a PF02238.15 OQS02691.1 - 0.16 12.4 0.0 0.31 11.5 0.0 1.5 1 0 0 1 1 1 0 Cytochrome c oxidase subunit VII IQ PF00612.27 OQS02692.1 - 1.1e-05 24.7 26.7 0.00082 19.0 0.1 5.7 6 0 0 6 6 6 4 IQ calmodulin-binding motif Mg_trans_NIPA PF05653.14 OQS02693.1 - 1.4e-40 139.3 11.4 5.5e-40 137.3 11.4 1.7 1 1 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.20 OQS02693.1 - 6.5e-07 29.6 3.6 6.5e-07 29.6 3.6 3.6 2 2 2 4 4 4 1 EamA-like transporter family DUF373 PF04123.13 OQS02693.1 - 0.00071 19.1 4.9 0.013 15.0 3.1 2.1 1 1 1 2 2 2 1 Domain of unknown function (DUF373) YhhN PF07947.14 OQS02693.1 - 0.0062 16.2 6.9 0.0062 16.2 6.9 2.1 1 1 1 2 2 2 1 YhhN family DUF3382 PF11862.8 OQS02693.1 - 0.016 15.4 1.4 4.8 7.5 0.0 2.9 1 1 1 2 2 2 0 Domain of unknown function (DUF3382) DMT_6 PF04342.12 OQS02693.1 - 0.061 13.5 0.4 0.061 13.5 0.4 2.6 3 0 0 3 3 3 0 Putative member of DMT superfamily (DUF486) Jagunal PF07086.12 OQS02693.1 - 0.22 11.6 7.1 2.9 7.9 0.1 2.8 1 1 2 3 3 3 0 Jagunal, ER re-organisation during oogenesis DUF2304 PF10066.9 OQS02693.1 - 6.4 7.0 11.6 0.082 13.1 1.7 2.8 2 1 0 3 3 3 0 Uncharacterized conserved protein (DUF2304) CRAL_TRIO PF00650.20 OQS02694.1 - 1.3e-53 181.0 0.0 4.5e-27 94.7 0.0 2.8 3 0 0 3 3 3 2 CRAL/TRIO domain DEP PF00610.21 OQS02694.1 - 1.7e-13 50.4 0.1 5.8e-06 26.3 0.0 2.6 2 0 0 2 2 2 2 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) PH PF00169.29 OQS02694.1 - 5.4e-10 39.7 0.1 1.4e-09 38.4 0.1 1.8 1 0 0 1 1 1 1 PH domain CRAL_TRIO_2 PF13716.6 OQS02694.1 - 1.1e-06 28.9 0.0 0.00055 20.1 0.0 2.5 2 0 0 2 2 2 2 Divergent CRAL/TRIO domain GST_C_5 PF16865.5 OQS02696.1 - 2.4e-14 53.8 0.0 5.3e-14 52.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 OQS02696.1 - 1.3e-11 44.7 0.0 2.4e-11 43.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 OQS02696.1 - 3.2e-10 40.2 0.1 4e-09 36.7 0.0 2.8 1 1 1 3 3 3 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 OQS02696.1 - 3e-08 33.6 0.1 4.9e-08 32.9 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 OQS02696.1 - 7.3e-07 29.4 0.0 1.5e-06 28.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 OQS02696.1 - 1.1e-05 25.5 0.1 2.1e-05 24.6 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 OQS02696.1 - 0.0013 18.9 0.0 0.0025 18.0 0.0 1.5 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain CemA PF03040.14 OQS02696.1 - 0.0016 18.4 0.0 0.0022 18.0 0.0 1.1 1 0 0 1 1 1 1 CemA family DUF3188 PF11384.8 OQS02697.1 - 0.29 10.9 3.9 2.4 8.0 1.3 3.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3188) GST_C_5 PF16865.5 OQS02700.1 - 5.1e-13 49.6 0.1 3.6e-12 46.8 0.0 2.1 1 1 1 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 OQS02700.1 - 1e-10 41.9 0.0 1.8e-10 41.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 OQS02700.1 - 1.9e-10 40.9 0.0 5e-10 39.6 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 OQS02700.1 - 8.8e-09 35.6 0.0 1.5e-08 34.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 OQS02700.1 - 6.3e-06 26.1 0.2 1.1e-05 25.3 0.2 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 OQS02700.1 - 5e-05 23.4 0.0 0.00012 22.3 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 OQS02700.1 - 0.00012 22.2 0.0 0.00019 21.6 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Defensin_beta PF00711.19 OQS02701.1 - 1.4 9.0 14.5 6 7.0 0.1 3.3 2 1 1 3 3 3 0 Beta defensin p450 PF00067.22 OQS02702.1 - 1.6e-30 106.2 0.0 1.3e-17 63.7 0.0 3.2 1 1 1 2 2 2 2 Cytochrome P450 CPSF_A PF03178.15 OQS02703.1 - 2.9e-63 214.1 0.0 5.8e-63 213.1 0.0 1.5 1 0 0 1 1 1 1 CPSF A subunit region MMS1_N PF10433.9 OQS02703.1 - 1.2e-30 106.6 0.0 3.7e-30 105.0 0.0 1.7 1 1 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term Chromate_transp PF02417.15 OQS02705.1 - 1.5e-61 207.1 42.4 2.6e-34 118.6 20.0 2.5 2 1 0 2 2 2 2 Chromate transporter eRF1_1 PF03463.15 OQS02706.1 - 2.4e-47 160.1 0.2 4.9e-47 159.1 0.2 1.5 1 0 0 1 1 1 1 eRF1 domain 1 eRF1_2 PF03464.15 OQS02706.1 - 2e-28 99.3 0.1 3.4e-28 98.6 0.1 1.4 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.15 OQS02706.1 - 1.1e-23 83.8 0.0 2.6e-23 82.6 0.0 1.7 1 0 0 1 1 1 1 eRF1 domain 3 bZIP_1 PF00170.21 OQS02707.1 - 7.3e-06 26.0 5.0 7.3e-06 26.0 5.0 2.8 3 0 0 3 3 3 1 bZIP transcription factor bZIP_2 PF07716.15 OQS02707.1 - 0.0011 19.0 3.0 0.0011 19.0 3.0 2.7 3 0 0 3 3 3 1 Basic region leucine zipper Fer4_20 PF14691.6 OQS02707.1 - 0.096 12.5 0.1 0.24 11.2 0.1 1.6 1 0 0 1 1 1 0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster TSC22 PF01166.18 OQS02707.1 - 0.19 12.0 8.9 1.3 9.4 2.0 3.5 3 0 0 3 3 3 0 TSC-22/dip/bun family SAS4 PF15460.6 OQS02707.1 - 0.57 10.3 6.1 3.4 7.8 1.2 2.6 1 1 1 2 2 2 0 Something about silencing, SAS, complex subunit 4 BT1 PF03092.16 OQS02708.1 - 1.3e-08 33.6 7.6 7.1e-08 31.1 1.8 2.7 2 1 0 2 2 2 2 BT1 family SieB PF14163.6 OQS02708.1 - 0.039 13.5 0.6 3.3 7.2 0.1 2.8 3 0 0 3 3 3 0 Super-infection exclusion protein B Phage_holin_4_1 PF05105.12 OQS02708.1 - 0.095 12.8 4.3 2.8 8.1 0.2 3.9 2 1 1 3 3 3 0 Bacteriophage holin family TctB PF07331.11 OQS02708.1 - 7.7 6.8 21.7 15 5.9 0.3 4.4 2 1 2 4 4 4 0 Tripartite tricarboxylate transporter TctB family Choline_transpo PF04515.12 OQS02713.1 - 8.1e-24 84.4 8.4 1.6e-22 80.1 5.2 2.2 1 1 1 2 2 2 2 Plasma-membrane choline transporter Uma2 PF05685.12 OQS02714.1 - 0.017 14.7 0.0 0.026 14.0 0.0 1.2 1 0 0 1 1 1 0 Putative restriction endonuclease DUF1057 PF06342.12 OQS02715.1 - 4.1e-43 147.5 0.0 4.1e-21 75.3 0.0 2.1 1 1 0 2 2 2 2 Alpha/beta hydrolase of unknown function (DUF1057) Abhydrolase_6 PF12697.7 OQS02715.1 - 3.5e-28 99.7 0.0 1.1e-13 52.3 0.0 2.2 2 0 0 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 OQS02715.1 - 4e-24 85.6 1.6 8e-10 38.8 0.0 4.2 3 1 0 4 4 4 3 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 OQS02715.1 - 5.4e-20 71.7 0.1 2e-09 37.1 0.0 3.1 2 2 0 2 2 2 2 Serine aminopeptidase, S33 DUF676 PF05057.14 OQS02715.1 - 6.2e-08 32.4 0.0 0.0033 16.9 0.0 2.3 2 0 0 2 2 2 2 Putative serine esterase (DUF676) Ser_hydrolase PF06821.13 OQS02715.1 - 1.6e-07 31.3 2.1 0.0079 16.1 0.1 3.2 3 0 0 3 3 3 2 Serine hydrolase Thioesterase PF00975.20 OQS02715.1 - 4.6e-05 23.7 0.0 0.2 11.7 0.0 2.5 2 0 0 2 2 2 2 Thioesterase domain PGAP1 PF07819.13 OQS02715.1 - 0.00021 21.1 0.6 0.12 12.1 0.1 3.7 4 0 0 4 4 4 1 PGAP1-like protein BAAT_C PF08840.11 OQS02715.1 - 0.001 19.0 0.4 1.8 8.5 0.1 2.5 2 1 0 2 2 2 2 BAAT / Acyl-CoA thioester hydrolase C terminal PAF-AH_p_II PF03403.13 OQS02715.1 - 0.0012 17.5 0.3 0.16 10.5 0.0 2.2 2 0 0 2 2 2 2 Platelet-activating factor acetylhydrolase, isoform II Esterase PF00756.20 OQS02715.1 - 0.0033 17.1 1.5 1.4 8.5 0.1 2.4 2 0 0 2 2 2 2 Putative esterase Abhydrolase_8 PF06259.12 OQS02715.1 - 0.0081 15.8 0.8 4.9 6.7 0.0 2.8 3 0 0 3 3 3 2 Alpha/beta hydrolase Abhydrolase_2 PF02230.16 OQS02715.1 - 0.0087 15.9 0.5 5.4 6.7 0.0 2.9 3 0 0 3 3 3 1 Phospholipase/Carboxylesterase Abhydrolase_5 PF12695.7 OQS02715.1 - 0.013 15.3 0.2 5.6 6.7 0.0 2.4 2 0 0 2 2 2 0 Alpha/beta hydrolase family DUF2974 PF11187.8 OQS02715.1 - 0.016 14.8 0.1 4.2 6.9 0.0 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF2974) RMMBL PF07521.12 OQS02715.1 - 0.054 13.4 0.0 12 5.9 0.0 2.8 3 0 0 3 3 3 0 Zn-dependent metallo-hydrolase RNA specificity domain DUF915 PF06028.11 OQS02715.1 - 0.066 12.5 0.3 3.3 7.0 0.0 3.1 4 0 0 4 4 4 0 Alpha/beta hydrolase of unknown function (DUF915) Acyl_transf_1 PF00698.21 OQS02715.1 - 0.098 12.1 2.1 5.6 6.4 0.1 2.3 2 0 0 2 2 2 0 Acyl transferase domain LCAT PF02450.15 OQS02715.1 - 0.12 11.5 0.3 1.6 7.8 0.0 2.1 2 0 0 2 2 2 0 Lecithin:cholesterol acyltransferase LIDHydrolase PF10230.9 OQS02715.1 - 0.13 11.8 0.1 2 7.9 0.0 2.5 2 0 0 2 2 2 0 Lipid-droplet associated hydrolase TRL PF13146.6 OQS02715.1 - 0.18 12.1 0.3 19 5.6 0.0 3.0 3 0 0 3 3 3 0 TRL-like protein family Lipase_3 PF01764.25 OQS02715.1 - 0.47 10.3 2.6 14 5.6 0.0 2.5 2 0 0 2 2 2 0 Lipase (class 3) Iwr1 PF08574.10 OQS02717.1 - 6.3e-10 39.9 12.0 6.3e-10 39.9 12.0 3.4 3 0 0 3 3 3 1 Transcription factor Iwr1 Ank_2 PF12796.7 OQS02717.1 - 0.00057 20.4 0.0 0.0011 19.5 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) DUF1057 PF06342.12 OQS02718.1 - 1.1e-23 83.7 0.0 1.8e-23 83.0 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1057) Abhydrolase_1 PF00561.20 OQS02718.1 - 3.1e-15 56.5 0.0 6.8e-14 52.1 0.0 2.0 2 0 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 OQS02718.1 - 1.1e-14 54.3 0.0 4.6e-14 52.3 0.0 1.8 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 OQS02718.1 - 1.1e-13 52.3 0.0 1.4e-13 52.0 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.20 OQS02718.1 - 3.5e-07 30.6 0.0 6.7e-07 29.7 0.0 1.5 1 0 0 1 1 1 1 Thioesterase domain DUF676 PF05057.14 OQS02718.1 - 0.0024 17.4 0.0 0.0036 16.8 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_3 PF07859.13 OQS02718.1 - 0.028 14.3 0.0 0.04 13.8 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_5 PF12695.7 OQS02718.1 - 0.029 14.1 0.0 0.1 12.4 0.0 1.9 2 0 0 2 2 2 0 Alpha/beta hydrolase family Ser_hydrolase PF06821.13 OQS02718.1 - 0.079 12.8 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 Serine hydrolase LIDHydrolase PF10230.9 OQS02718.1 - 0.1 12.1 0.0 0.17 11.4 0.0 1.2 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase Lipase_3 PF01764.25 OQS02718.1 - 0.13 12.2 0.1 1.1 9.1 0.0 2.0 2 0 0 2 2 2 0 Lipase (class 3) Ndr PF03096.14 OQS02718.1 - 0.14 10.9 0.0 0.17 10.5 0.0 1.2 1 0 0 1 1 1 0 Ndr family RasGEF PF00617.19 OQS02719.1 - 3.6e-26 92.5 0.1 1.1e-25 90.9 0.1 1.8 1 1 0 1 1 1 1 RasGEF domain Leu_Phe_trans PF03588.14 OQS02719.1 - 1.6e-25 89.6 0.0 2.9e-25 88.8 0.0 1.5 1 0 0 1 1 1 1 Leucyl/phenylalanyl-tRNA protein transferase RasGEF_N PF00618.20 OQS02719.1 - 3.8e-14 52.8 0.3 3.2e-13 49.8 0.2 2.3 2 0 0 2 2 2 1 RasGEF N-terminal motif Acetyltransf_6 PF13480.7 OQS02719.1 - 0.034 14.3 0.1 0.063 13.4 0.1 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Orthopox_A36R PF05950.11 OQS02720.1 - 0.057 13.6 0.0 0.085 13.0 0.0 1.2 1 0 0 1 1 1 0 Orthopoxvirus A36R protein cNMP_binding PF00027.29 OQS02721.1 - 5.1e-15 55.3 0.0 1.2e-14 54.1 0.0 1.7 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain PI3_PI4_kinase PF00454.27 OQS02722.1 - 1.9e-32 113.1 0.0 4.9e-32 111.7 0.0 1.7 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase DnaJ PF00226.31 OQS02722.1 - 4.1e-09 36.4 0.1 1.1e-08 35.1 0.1 1.8 1 0 0 1 1 1 1 DnaJ domain TPR_2 PF07719.17 OQS02722.1 - 0.0058 16.7 10.5 0.092 12.9 0.2 4.5 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 OQS02722.1 - 0.011 16.5 3.2 18 6.5 0.6 4.4 3 1 1 4 4 4 0 Tetratricopeptide repeat DUF4135 PF13575.6 OQS02722.1 - 0.011 15.1 0.0 0.079 12.3 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4135) TPR_16 PF13432.6 OQS02722.1 - 0.033 14.8 3.0 5.4 7.8 2.3 3.9 3 1 1 4 4 4 0 Tetratricopeptide repeat HCMV_UL139 PF12507.8 OQS02722.1 - 0.041 14.3 2.8 0.075 13.4 0.2 2.3 2 0 0 2 2 2 0 Human Cytomegalovirus UL139 protein ATP13 PF12921.7 OQS02722.1 - 0.097 12.5 0.0 0.31 10.9 0.0 1.8 1 1 0 1 1 1 0 Mitochondrial ATPase expression TPR_19 PF14559.6 OQS02722.1 - 0.12 12.9 7.2 33 5.1 0.8 4.7 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_9 PF13371.6 OQS02722.1 - 0.15 12.2 5.6 1.6 9.0 0.2 3.4 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_8 PF13181.6 OQS02722.1 - 0.37 11.1 4.8 4.7 7.7 0.0 4.4 5 0 0 5 5 4 0 Tetratricopeptide repeat Hom_end_hint PF05203.16 OQS02723.1 - 0.027 14.4 0.0 0.033 14.1 0.0 1.1 1 0 0 1 1 1 0 Hom_end-associated Hint tRNA-synt_1g PF09334.11 OQS02725.1 - 2.4e-102 342.6 2.6 1.1e-100 337.1 1.1 2.5 2 1 0 2 2 2 1 tRNA synthetases class I (M) Peptidase_M20 PF01546.28 OQS02725.1 - 1.6e-32 112.9 0.0 3.6e-32 111.8 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 tRNA-synt_1 PF00133.22 OQS02725.1 - 1.8e-25 89.3 1.5 1.3e-12 46.9 0.7 3.0 2 1 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1e PF01406.19 OQS02725.1 - 1.8e-11 44.0 0.0 9.4e-05 21.9 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain M20_dimer PF07687.14 OQS02725.1 - 2.2e-09 37.2 0.0 4.5e-09 36.2 0.0 1.6 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 OQS02725.1 - 3.7e-06 26.8 0.0 3.9e-05 23.4 0.0 2.3 2 0 0 2 2 2 1 Peptidase family M28 Anticodon_1 PF08264.13 OQS02725.1 - 0.0068 16.4 0.2 0.017 15.1 0.2 1.7 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA Patatin PF01734.22 OQS02726.1 - 4e-10 40.2 1.4 0.00031 21.0 1.4 2.1 1 1 0 2 2 2 2 Patatin-like phospholipase SAT PF16073.5 OQS02726.1 - 0.012 15.4 0.3 0.02 14.6 0.3 1.3 1 0 0 1 1 1 0 Starter unit:ACP transacylase in aflatoxin biosynthesis YchF-GTPase_C PF06071.13 OQS02727.1 - 4e-35 119.9 0.0 9e-35 118.7 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.23 OQS02727.1 - 2.4e-24 85.6 0.1 5.6e-24 84.4 0.0 1.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 OQS02727.1 - 6e-08 32.4 0.0 1.4e-07 31.2 0.0 1.5 1 1 0 1 1 1 1 Ferrous iron transport protein B MeaB PF03308.16 OQS02727.1 - 0.0039 16.2 0.0 0.0078 15.2 0.0 1.4 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB ABC_tran PF00005.27 OQS02727.1 - 0.036 14.6 0.0 0.098 13.2 0.0 1.7 1 0 0 1 1 1 0 ABC transporter AAA_18 PF13238.6 OQS02727.1 - 0.084 13.4 0.0 0.25 11.9 0.0 1.9 2 0 0 2 2 2 0 AAA domain Dynamin_N PF00350.23 OQS02727.1 - 0.097 12.7 0.0 2.2 8.3 0.0 2.3 1 1 0 2 2 2 0 Dynamin family Roc PF08477.13 OQS02727.1 - 0.11 12.7 0.0 0.33 11.2 0.0 1.7 1 1 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase RsgA_GTPase PF03193.16 OQS02727.1 - 0.12 12.3 0.1 0.32 10.9 0.0 1.7 2 0 0 2 2 2 0 RsgA GTPase SPACA9 PF15120.6 OQS02727.1 - 0.13 12.1 0.1 0.24 11.1 0.1 1.5 1 1 0 1 1 1 0 Sperm acrosome-associated protein 9 GTP_EFTU PF00009.27 OQS02727.1 - 0.18 11.3 0.5 0.68 9.4 0.0 2.1 3 0 0 3 3 3 0 Elongation factor Tu GTP binding domain Peptidase_S10 PF00450.22 OQS02728.1 - 9.5e-122 407.4 0.3 1.1e-121 407.1 0.3 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase DUF2967 PF11179.8 OQS02729.1 - 0.25 9.4 8.4 0.33 9.0 8.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2967) Ribosomal_S18 PF01084.20 OQS02729.1 - 7.9 6.8 10.0 0.17 12.1 1.4 2.5 2 0 0 2 2 2 0 Ribosomal protein S18 EGF_2 PF07974.13 OQS02730.1 - 0.00024 21.4 44.5 0.0021 18.4 10.7 11.8 12 2 2 14 14 14 6 EGF-like domain EGF PF00008.27 OQS02730.1 - 0.0015 18.8 19.9 0.0033 17.7 7.3 10.8 11 2 0 11 11 11 3 EGF-like domain hEGF PF12661.7 OQS02730.1 - 0.01 16.5 3.8 0.01 16.5 3.8 13.4 11 4 2 13 13 13 0 Human growth factor-like EGF Zip PF02535.22 OQS02731.1 - 2.1e-32 112.7 2.6 3.1e-32 112.1 2.0 1.5 2 0 0 2 2 2 1 ZIP Zinc transporter Asp PF00026.23 OQS02731.1 - 2.4e-21 76.5 0.7 4.6e-21 75.6 0.7 1.4 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 OQS02731.1 - 9.3e-14 52.0 2.1 4.8e-13 49.7 2.3 2.0 2 0 0 2 2 2 1 Xylanase inhibitor N-terminal TAXi_C PF14541.6 OQS02731.1 - 1.4e-12 47.7 0.3 3.4e-12 46.4 0.0 1.8 2 0 0 2 2 2 1 Xylanase inhibitor C-terminal Myb_DNA-binding PF00249.31 OQS02731.1 - 4.9e-11 42.6 0.7 1.1e-10 41.6 0.4 1.8 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OQS02731.1 - 0.014 15.3 0.5 0.033 14.1 0.5 1.6 1 0 0 1 1 1 0 Myb DNA-binding like DUF659 PF04937.15 OQS02731.1 - 0.037 13.9 0.1 0.073 12.9 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF 659) Myb_DNA-bind_6 PF13921.6 OQS02731.1 - 0.11 12.8 0.6 0.25 11.6 0.6 1.7 1 0 0 1 1 1 0 Myb-like DNA-binding domain RabGAP-TBC PF00566.18 OQS02732.1 - 6.1e-41 140.4 0.8 9.3e-41 139.8 0.8 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain LSM PF01423.22 OQS02733.1 - 1.8e-17 62.8 0.3 2.1e-17 62.6 0.3 1.1 1 0 0 1 1 1 1 LSM domain Hfq PF17209.3 OQS02733.1 - 0.003 17.2 0.0 0.0048 16.5 0.0 1.3 1 0 0 1 1 1 1 Hfq protein DUF3446 PF11928.8 OQS02734.1 - 0.88 9.9 4.8 5.6 7.3 0.1 2.5 2 0 0 2 2 2 0 Early growth response N-terminal domain S10_plectin PF03501.15 OQS02735.1 - 7.4e-45 151.0 0.2 8.9e-45 150.7 0.2 1.1 1 0 0 1 1 1 1 Plectin/S10 domain Ilm1 PF10311.9 OQS02735.1 - 0.18 11.5 0.2 0.26 10.9 0.2 1.1 1 0 0 1 1 1 0 Increased loss of mitochondrial DNA protein 1 Ribosomal_L15e PF00827.17 OQS02736.1 - 1.1e-87 292.7 13.5 1.3e-87 292.5 13.5 1.0 1 0 0 1 1 1 1 Ribosomal L15 UBA_6 PF18039.1 OQS02736.1 - 0.15 12.0 0.0 0.3 11.1 0.0 1.4 1 0 0 1 1 1 0 UBA-like domain Pho86 PF11124.8 OQS02737.1 - 0.097 12.1 0.2 0.22 11.0 0.2 1.5 1 0 0 1 1 1 0 Inorganic phosphate transporter Pho86 TPX2 PF06886.11 OQS02738.1 - 0.0018 18.4 17.2 0.0018 18.4 17.2 2.2 2 0 0 2 2 2 1 Targeting protein for Xklp2 (TPX2) Tox-GHH PF15636.6 OQS02738.1 - 9.8 6.2 10.3 1.8 8.6 4.9 2.5 3 0 0 3 3 3 0 GHH signature containing HNH/Endo VII superfamily nuclease toxin Arginase PF00491.21 OQS02739.1 - 8.9e-56 189.4 0.2 1.1e-55 189.1 0.2 1.1 1 0 0 1 1 1 1 Arginase family UPF0489 PF12640.7 OQS02739.1 - 0.14 12.4 0.1 0.21 11.8 0.1 1.3 1 0 0 1 1 1 0 UPF0489 domain Sec7 PF01369.20 OQS02740.1 - 9.3e-69 230.8 0.1 3e-68 229.1 0.1 1.9 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.7 OQS02740.1 - 1.2e-42 145.4 2.2 1.2e-42 145.4 2.2 2.5 2 0 0 2 2 2 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.10 OQS02740.1 - 2.7e-32 110.5 1.0 1.6e-29 101.6 0.1 4.3 4 0 0 4 4 4 1 Domain of unknown function (DUF1981) DCB PF16213.5 OQS02740.1 - 1.5e-20 73.6 14.0 5.9e-20 71.7 3.1 3.9 3 0 0 3 3 3 2 Dimerisation and cyclophilin-binding domain of Mon2 Mon2_C PF16206.5 OQS02740.1 - 8e-05 21.0 0.0 0.0002 19.7 0.0 1.6 1 0 0 1 1 1 1 C-terminal region of Mon2 protein DUF4604 PF15377.6 OQS02740.1 - 0.0069 16.8 0.7 0.0069 16.8 0.7 2.5 3 0 0 3 3 3 1 Domain of unknown function (DUF4604) Ycf54 PF10674.9 OQS02740.1 - 0.026 14.8 0.8 0.12 12.6 0.8 2.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2488) ASF1_hist_chap PF04729.13 OQS02741.1 - 4.8e-68 228.0 0.1 6.2e-68 227.6 0.1 1.1 1 0 0 1 1 1 1 ASF1 like histone chaperone Methyltransf_25 PF13649.6 OQS02742.1 - 4.2e-13 49.8 0.1 1.5e-12 48.0 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 OQS02742.1 - 4.7e-11 42.7 0.0 8.8e-11 41.8 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 OQS02742.1 - 1.5e-10 41.0 0.0 2.1e-10 40.5 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_11 PF08241.12 OQS02742.1 - 2.9e-10 40.6 0.0 8.8e-10 39.1 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OQS02742.1 - 4e-07 30.0 0.0 1.4e-06 28.2 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OQS02742.1 - 4.6e-07 30.5 0.0 9.2e-07 29.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.11 OQS02742.1 - 6.7e-06 25.2 0.1 9.6e-06 24.7 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) MTS PF05175.14 OQS02742.1 - 4.8e-05 23.0 0.1 7.5e-05 22.3 0.1 1.2 1 0 0 1 1 1 1 Methyltransferase small domain CMAS PF02353.20 OQS02742.1 - 6.2e-05 22.4 0.0 8.5e-05 22.0 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_18 PF12847.7 OQS02742.1 - 7.8e-05 22.6 0.1 0.00014 21.8 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 OQS02742.1 - 0.0006 19.8 0.0 0.00081 19.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.18 OQS02742.1 - 0.0016 17.8 0.1 0.003 16.9 0.1 1.4 1 0 0 1 1 1 1 O-methyltransferase domain FtsJ PF01728.19 OQS02742.1 - 0.008 16.3 0.0 0.02 15.0 0.0 1.6 2 0 0 2 2 2 1 FtsJ-like methyltransferase PRMT5 PF05185.16 OQS02742.1 - 0.012 15.5 0.0 0.022 14.6 0.0 1.4 1 0 0 1 1 1 0 PRMT5 arginine-N-methyltransferase Methyltransf_24 PF13578.6 OQS02742.1 - 0.019 16.0 0.0 0.033 15.2 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain PRMT5_C PF17286.2 OQS02742.1 - 0.041 13.8 0.0 0.065 13.1 0.0 1.3 1 0 0 1 1 1 0 PRMT5 oligomerisation domain Methyltransf_16 PF10294.9 OQS02742.1 - 0.062 13.0 0.1 0.091 12.5 0.1 1.2 1 0 0 1 1 1 0 Lysine methyltransferase TehB PF03848.14 OQS02742.1 - 0.073 12.5 0.5 0.26 10.7 0.5 1.9 1 1 0 1 1 1 0 Tellurite resistance protein TehB PCMT PF01135.19 OQS02742.1 - 0.081 12.7 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Met_10 PF02475.16 OQS02742.1 - 0.095 12.4 0.0 0.15 11.8 0.0 1.2 1 0 0 1 1 1 0 Met-10+ like-protein DOT1 PF08123.13 OQS02742.1 - 0.13 11.7 0.1 0.23 11.0 0.1 1.3 1 0 0 1 1 1 0 Histone methylation protein DOT1 Bromodomain PF00439.25 OQS02743.1 - 6.5e-19 67.8 0.2 1.5e-18 66.7 0.2 1.6 1 0 0 1 1 1 1 Bromodomain PRP1_N PF06424.12 OQS02744.1 - 0.12 12.7 6.7 0.028 14.8 3.4 1.8 2 0 0 2 2 2 0 PRP1 splicing factor, N-terminal KH_8 PF17903.1 OQS02745.1 - 7e-32 109.4 1.9 8.2e-32 109.1 0.1 2.0 2 0 0 2 2 2 1 Krr1 KH1 domain Pfg27 PF09216.10 OQS02745.1 - 0.066 13.0 0.7 0.12 12.2 0.1 1.7 2 0 0 2 2 2 0 Pfg27 CALM_bind PF16025.5 OQS02745.1 - 0.14 12.6 3.3 0.3 11.6 3.3 1.6 1 0 0 1 1 1 0 Calcium-dependent calmodulin binding DUF1768 PF08719.11 OQS02746.1 - 7.2e-18 65.3 0.3 8.5e-18 65.1 0.3 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) SpoU_sub_bind PF08032.12 OQS02746.1 - 0.0081 16.4 0.1 0.18 12.1 0.1 2.7 3 0 0 3 3 3 1 RNA 2'-O ribose methyltransferase substrate binding Phage_30_3 PF08010.11 OQS02746.1 - 0.0096 15.7 0.0 0.015 15.1 0.0 1.4 1 1 0 1 1 1 1 Bacteriophage protein GP30.3 Acatn PF13000.7 OQS02747.1 - 5.5e-118 394.8 23.2 5.1e-70 236.5 8.7 3.5 1 1 2 3 3 3 3 Acetyl-coenzyme A transporter 1 VanZ PF04892.12 OQS02747.1 - 0.18 12.4 6.3 0.059 14.0 0.9 2.8 3 0 0 3 3 3 0 VanZ like family DUF5391 PF17369.2 OQS02747.1 - 0.55 10.3 4.5 0.77 9.8 3.0 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5391) DUF4576 PF15144.6 OQS02747.1 - 2 8.4 4.2 0.37 10.7 0.3 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4576) CrgA PF06781.12 OQS02747.1 - 3.7 7.7 5.4 6 7.0 0.2 3.2 3 0 0 3 3 3 0 Cell division protein CrgA Mannosyl_trans3 PF11051.8 OQS02749.1 - 4.9e-31 108.1 0.0 6.1e-20 71.7 0.0 2.2 1 1 0 2 2 2 2 Mannosyltransferase putative Peptidase_C1 PF00112.23 OQS02750.1 - 2.1e-99 332.0 23.7 3.8e-51 174.3 3.2 2.7 3 0 0 3 3 3 2 Papain family cysteine protease Ricin_B_lectin PF00652.22 OQS02750.1 - 9.7e-29 100.2 15.7 2.9e-14 53.4 6.9 2.7 2 0 0 2 2 2 2 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.6 OQS02750.1 - 7.9e-09 36.1 13.9 0.00016 22.3 1.1 4.1 1 1 2 3 3 3 3 Ricin-type beta-trefoil lectin domain-like CDtoxinA PF03498.14 OQS02750.1 - 2.1e-07 30.6 2.6 0.00029 20.5 0.6 2.8 1 1 1 2 2 2 2 Cytolethal distending toxin A/C domain Cys_box PF17869.1 OQS02750.1 - 0.00042 20.4 1.5 0.28 11.3 0.2 2.8 2 0 0 2 2 2 2 Anosmin cysteine rich domain TraO PF10626.9 OQS02750.1 - 0.031 14.0 0.1 7.5 6.3 0.0 2.4 2 0 0 2 2 2 0 Conjugative transposon protein TraO Inhibitor_I29 PF08246.12 OQS02750.1 - 0.07 13.6 6.2 1.4 9.4 0.2 3.2 3 0 0 3 3 3 0 Cathepsin propeptide inhibitor domain (I29) HRDC PF00570.23 OQS02750.1 - 0.26 11.3 1.6 14 5.7 0.1 2.5 2 0 0 2 2 2 0 HRDC domain PNP_UDP_1 PF01048.20 OQS02751.1 - 2.9e-42 144.5 3.8 4.3e-23 81.8 0.2 2.5 2 0 0 2 2 2 2 Phosphorylase superfamily Na_H_Exchanger PF00999.21 OQS02751.1 - 7.1e-36 123.8 43.0 1.1e-35 123.2 43.0 1.2 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family DUF4164 PF13747.6 OQS02751.1 - 0.15 12.3 1.1 0.43 10.9 1.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4164) Peptidase_S49_N PF08496.10 OQS02751.1 - 0.3 11.1 7.9 4.7 7.2 0.1 3.3 3 0 0 3 3 3 0 Peptidase family S49 N-terminal TPR_11 PF13414.6 OQS02751.1 - 2.1 8.1 5.2 19 5.0 0.0 3.8 4 0 0 4 4 4 0 TPR repeat Trypan_PARP PF05887.11 OQS02752.1 - 0.0032 17.5 2.8 0.0059 16.6 2.8 1.4 1 0 0 1 1 1 1 Procyclic acidic repetitive protein (PARP) DUF1803 PF08820.10 OQS02752.1 - 0.14 12.2 2.0 1.1 9.3 0.5 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1803) ComGF PF15980.5 OQS02752.1 - 0.27 11.6 1.8 1.3 9.4 0.1 2.7 2 0 0 2 2 2 0 Putative Competence protein ComGF NADH-UOR_E PF16514.5 OQS02752.1 - 0.3 11.4 2.3 25 5.3 0.0 3.6 3 0 0 3 3 3 0 putative NADH-ubiquinone oxidoreductase chain E DUF1319 PF07028.11 OQS02752.1 - 1.6 9.0 9.1 1.1 9.5 0.4 3.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1319) AAA_6 PF12774.7 OQS02753.1 - 5.4e-162 538.3 0.0 6.2e-160 531.5 0.0 2.6 2 0 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 OQS02753.1 - 4e-129 431.2 7.2 4e-129 431.2 7.2 2.7 2 1 0 2 2 2 1 Dynein heavy chain, N-terminal region 2 AAA_8 PF12780.7 OQS02753.1 - 4.1e-104 347.5 0.6 2.5e-103 344.9 0.0 2.7 3 0 0 3 3 2 1 P-loop containing dynein motor region D4 Dynein_C PF18199.1 OQS02753.1 - 7e-100 334.2 0.0 2.7e-97 325.7 0.0 3.0 3 0 0 3 3 2 1 Dynein heavy chain C-terminal domain AAA_9 PF12781.7 OQS02753.1 - 1.8e-91 305.2 0.4 1.8e-91 305.2 0.4 2.7 3 0 0 3 3 2 1 ATP-binding dynein motor region AAA_7 PF12775.7 OQS02753.1 - 2.1e-71 239.2 0.2 3.4e-67 225.5 0.0 3.6 3 0 0 3 3 3 1 P-loop containing dynein motor region MT PF12777.7 OQS02753.1 - 7.8e-49 166.5 11.2 7.8e-49 166.5 11.2 2.6 3 0 0 3 3 3 1 Microtubule-binding stalk of dynein motor AAA_lid_11 PF18198.1 OQS02753.1 - 1.6e-48 164.6 0.0 4.1e-48 163.3 0.0 1.8 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 OQS02753.1 - 5.6e-45 152.3 2.3 5e-42 142.8 0.0 4.1 4 0 0 4 4 3 1 Dynein heavy chain region D6 P-loop domain Dynein_AAA_lid PF17852.1 OQS02753.1 - 1.3e-19 70.6 0.1 4.5e-19 68.8 0.1 2.1 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_5 PF07728.14 OQS02753.1 - 3.8e-19 69.0 0.1 7.8e-07 29.2 0.0 6.4 5 1 0 5 5 5 3 AAA domain (dynein-related subfamily) AAA_lid_1 PF17857.1 OQS02753.1 - 6.3e-19 68.0 0.5 3.4e-18 65.7 0.1 2.6 3 0 0 3 3 1 1 AAA+ lid domain AAA_16 PF13191.6 OQS02753.1 - 2.9e-09 37.5 0.1 0.032 14.6 0.0 5.4 4 1 1 5 5 5 2 AAA ATPase domain AAA_22 PF13401.6 OQS02753.1 - 1.4e-08 35.1 0.1 0.053 13.8 0.0 5.4 5 0 0 5 5 4 1 AAA domain AAA PF00004.29 OQS02753.1 - 3.6e-07 30.7 0.9 0.24 11.8 0.0 5.1 5 0 0 5 5 4 1 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 OQS02753.1 - 2.9e-05 24.4 0.5 4.3 7.8 0.0 4.5 4 0 0 4 4 3 1 RNA helicase AAA_18 PF13238.6 OQS02753.1 - 3.2e-05 24.5 1.3 0.41 11.2 0.0 4.9 5 0 0 5 5 4 1 AAA domain T2SSE PF00437.20 OQS02753.1 - 0.0002 20.5 0.1 0.082 12.0 0.0 3.6 4 0 0 4 4 4 1 Type II/IV secretion system protein AAA_29 PF13555.6 OQS02753.1 - 0.00034 20.3 0.1 0.63 9.8 0.0 3.4 3 0 0 3 3 3 1 P-loop containing region of AAA domain ABC_tran PF00005.27 OQS02753.1 - 0.00057 20.4 0.7 1.3 9.5 0.0 4.1 3 0 0 3 3 3 1 ABC transporter Sigma54_activat PF00158.26 OQS02753.1 - 0.00071 19.3 0.3 0.062 13.0 0.0 2.9 3 0 0 3 3 2 1 Sigma-54 interaction domain NACHT PF05729.12 OQS02753.1 - 0.00088 19.2 0.1 0.29 11.1 0.0 3.8 4 0 0 4 4 3 1 NACHT domain DUF87 PF01935.17 OQS02753.1 - 0.0015 18.7 1.5 4.3 7.4 0.0 4.3 3 0 0 3 3 3 1 Helicase HerA, central domain Mg_chelatase PF01078.21 OQS02753.1 - 0.0031 16.9 0.2 0.94 8.8 0.0 3.1 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_30 PF13604.6 OQS02753.1 - 0.0033 17.2 1.9 13 5.4 0.1 3.9 4 0 0 4 4 4 0 AAA domain TsaE PF02367.17 OQS02753.1 - 0.0078 16.2 0.5 13 5.8 0.0 3.6 3 0 0 3 3 3 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE DUF815 PF05673.13 OQS02753.1 - 0.015 14.5 1.4 1.5 8.0 0.0 3.5 4 0 0 4 4 3 0 Protein of unknown function (DUF815) AAA_33 PF13671.6 OQS02753.1 - 0.022 14.9 0.0 3.3 7.9 0.0 3.2 2 0 0 2 2 2 0 AAA domain Cytidylate_kin PF02224.18 OQS02753.1 - 0.04 13.7 0.0 11 5.7 0.0 2.9 2 0 0 2 2 2 0 Cytidylate kinase FtsK_SpoIIIE PF01580.18 OQS02753.1 - 0.072 12.4 0.1 18 4.6 0.1 2.9 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_24 PF13479.6 OQS02753.1 - 0.14 11.9 0.1 28 4.3 0.0 3.2 4 0 0 4 4 2 0 AAA domain Suf PF05843.14 OQS02754.1 - 0.18 11.8 9.3 0.22 11.5 9.3 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) ANAPC1 PF12859.7 OQS02754.1 - 2.4 8.7 6.3 4.3 7.9 6.3 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 1 Hid1 PF12722.7 OQS02754.1 - 3.2 5.8 13.6 4 5.5 13.6 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein RabGAP-TBC PF00566.18 OQS02755.1 - 3.6e-25 88.9 0.1 7.5e-25 87.9 0.1 1.5 1 1 0 1 1 1 1 Rab-GTPase-TBC domain EF-hand_7 PF13499.6 OQS02755.1 - 0.0037 17.7 0.6 0.027 14.9 0.6 2.4 1 1 0 1 1 1 1 EF-hand domain pair Ydr279_N PF17745.1 OQS02755.1 - 0.0051 17.0 0.0 0.012 15.8 0.0 1.7 1 0 0 1 1 1 1 Ydr279p protein triple barrel domain EF-hand_6 PF13405.6 OQS02755.1 - 0.0079 16.0 0.1 9.4 6.5 0.0 3.6 3 0 0 3 3 3 1 EF-hand domain EF-hand_1 PF00036.32 OQS02755.1 - 0.014 14.9 0.0 12 5.7 0.0 3.3 3 0 0 3 3 3 0 EF hand CLASP_N PF12348.8 OQS02757.1 - 8.1e-18 64.8 2.0 8.1e-18 64.8 2.0 1.5 2 0 0 2 2 2 1 CLASP N terminal HEAT PF02985.22 OQS02757.1 - 0.19 12.1 0.5 2.7 8.5 0.1 3.0 3 0 0 3 3 3 0 HEAT repeat SPOB_ab PF14682.6 OQS02757.1 - 0.79 9.8 5.4 9.6 6.3 0.1 2.9 3 0 0 3 3 3 0 Sporulation initiation phospho-transferase B, C-terminal TFIIF_alpha PF05793.12 OQS02758.1 - 0.52 8.9 31.4 0.78 8.3 31.4 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) CDC45 PF02724.14 OQS02758.1 - 8.4 4.6 16.7 12 4.0 16.7 1.2 1 0 0 1 1 1 0 CDC45-like protein Pkinase PF00069.25 OQS02759.1 - 4.2e-67 226.3 0.0 5.4e-67 225.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQS02759.1 - 5.5e-34 117.6 0.0 7.2e-34 117.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OQS02759.1 - 5.9e-06 25.8 0.0 9.5e-06 25.1 0.0 1.3 1 0 0 1 1 1 1 Kinase-like KHA PF11834.8 OQS02759.1 - 4.6e-05 23.4 0.0 0.0001 22.3 0.0 1.6 1 0 0 1 1 1 1 KHA, dimerisation domain of potassium ion channel Kdo PF06293.14 OQS02759.1 - 0.0032 16.9 0.0 0.005 16.2 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 OQS02759.1 - 0.19 10.6 0.0 0.31 10.0 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain E1-E2_ATPase PF00122.20 OQS02761.1 - 3.2e-35 121.3 1.6 3.1e-21 75.7 0.1 2.8 2 1 1 3 3 3 2 E1-E2 ATPase Cation_ATPase_N PF00690.26 OQS02761.1 - 5.5e-15 54.8 0.0 1.2e-14 53.8 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase PF00702.26 OQS02761.1 - 0.17 12.2 1.2 0.26 11.5 0.4 1.8 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase Chorismate_synt PF01264.21 OQS02762.1 - 1.4e-134 448.0 0.0 1.7e-134 447.7 0.0 1.1 1 0 0 1 1 1 1 Chorismate synthase Thioredoxin PF00085.20 OQS02763.1 - 1e-53 179.6 0.0 5.6e-29 100.2 0.0 2.3 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_2 PF13098.6 OQS02763.1 - 6.7e-07 29.7 0.3 0.0009 19.7 0.0 2.8 2 1 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_8 PF13905.6 OQS02763.1 - 1.9e-05 24.9 0.1 0.21 11.9 0.0 3.7 2 2 2 4 4 4 2 Thioredoxin-like OST3_OST6 PF04756.13 OQS02763.1 - 4e-05 23.1 0.0 0.0081 15.5 0.0 2.5 2 1 0 2 2 2 2 OST3 / OST6 family, transporter family Thioredoxin_7 PF13899.6 OQS02763.1 - 0.00011 22.3 0.3 0.85 9.8 0.0 2.8 2 1 0 2 2 2 2 Thioredoxin-like AhpC-TSA PF00578.21 OQS02763.1 - 0.0012 18.8 0.1 2.1 8.3 0.0 2.6 3 0 0 3 3 3 2 AhpC/TSA family TraF PF13728.6 OQS02763.1 - 0.01 15.7 0.0 3.6 7.4 0.0 2.6 2 1 0 2 2 2 0 F plasmid transfer operon protein Thioredoxin_9 PF14595.6 OQS02763.1 - 0.024 14.4 0.2 4.2 7.1 0.0 2.4 2 0 0 2 2 2 0 Thioredoxin Redoxin PF08534.10 OQS02763.1 - 0.056 13.2 0.1 3.7 7.3 0.0 2.4 2 0 0 2 2 2 0 Redoxin TPPK_C PF12555.8 OQS02763.1 - 8.3 6.5 8.4 19 5.4 8.4 1.5 1 0 0 1 1 1 0 Thiamine pyrophosphokinase C terminal Kinesin PF00225.23 OQS02764.1 - 7e-82 275.0 0.3 7e-82 275.0 0.3 1.6 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 OQS02764.1 - 5.7e-23 81.5 0.1 1.6e-22 80.1 0.1 1.8 1 0 0 1 1 1 1 Microtubule binding Prominin PF05478.11 OQS02764.1 - 0.0035 15.4 5.4 0.0056 14.7 5.4 1.3 1 0 0 1 1 1 1 Prominin DUF4407 PF14362.6 OQS02764.1 - 0.0048 16.3 7.4 0.009 15.4 7.4 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4407) Tup_N PF08581.10 OQS02764.1 - 0.019 15.3 9.1 0.019 15.3 9.1 3.2 2 1 0 3 3 3 0 Tup N-terminal SEO_N PF14576.6 OQS02764.1 - 0.025 13.7 2.3 0.052 12.7 2.3 1.5 1 0 0 1 1 1 0 Sieve element occlusion N-terminus DUF16 PF01519.16 OQS02764.1 - 0.041 14.4 7.0 0.082 13.4 5.7 2.3 1 1 0 1 1 1 0 Protein of unknown function DUF16 Baculo_PEP_C PF04513.12 OQS02764.1 - 0.12 12.4 5.6 0.19 11.8 2.3 2.5 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Phage_GP20 PF06810.11 OQS02764.1 - 0.4 10.5 13.8 0.041 13.7 3.7 2.7 1 1 1 2 2 2 0 Phage minor structural protein GP20 SWI-SNF_Ssr4 PF08549.10 OQS02764.1 - 0.47 9.0 8.9 0.077 11.6 1.0 2.1 1 1 1 2 2 2 0 Fungal domain of unknown function (DUF1750) DUF3450 PF11932.8 OQS02764.1 - 0.47 9.7 9.9 0.095 12.0 6.1 1.9 2 1 0 2 2 2 0 Protein of unknown function (DUF3450) DUF4200 PF13863.6 OQS02764.1 - 0.73 10.3 15.8 1.8 8.9 15.8 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) DUF4472 PF14739.6 OQS02764.1 - 0.87 10.3 13.8 0.68 10.7 9.1 2.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4472) DUF1664 PF07889.12 OQS02764.1 - 1 9.4 4.0 2.7 8.0 4.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) V-SNARE PF05008.15 OQS02764.1 - 3.9 7.9 11.7 15 6.1 1.9 3.5 2 1 1 3 3 3 0 Vesicle transport v-SNARE protein N-terminus NPV_P10 PF05531.12 OQS02764.1 - 4.9 7.7 7.8 2.5 8.6 4.0 2.4 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein SlyX PF04102.12 OQS02764.1 - 8.7 7.1 8.4 4.2 8.0 4.1 2.6 1 1 2 3 3 3 0 SlyX Complex1_LYR PF05347.15 OQS02765.1 - 8.8e-15 54.5 0.8 1.2e-14 54.1 0.8 1.2 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 OQS02765.1 - 6.1e-05 23.7 0.2 6.8e-05 23.5 0.2 1.1 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR_1 PF13232.6 OQS02765.1 - 0.0048 17.5 0.1 0.0054 17.3 0.1 1.2 1 0 0 1 1 1 1 Complex1_LYR-like Ricin_B_lectin PF00652.22 OQS02766.1 - 9.4e-19 67.9 4.3 2.8e-13 50.2 3.5 2.3 2 0 0 2 2 2 2 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.6 OQS02766.1 - 1.2e-07 32.3 3.1 0.0009 19.9 0.4 3.4 2 1 1 3 3 3 3 Ricin-type beta-trefoil lectin domain-like DAGK_acc PF00609.19 OQS02767.1 - 6.4e-53 179.3 0.0 1.1e-52 178.5 0.0 1.4 1 0 0 1 1 1 1 Diacylglycerol kinase accessory domain DAGK_cat PF00781.24 OQS02767.1 - 1.2e-22 79.9 0.0 2.8e-22 78.7 0.0 1.6 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain C1_1 PF00130.22 OQS02767.1 - 2.2e-18 65.9 11.5 3.7e-10 39.5 3.4 2.5 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) C1_2 PF03107.16 OQS02767.1 - 0.0014 18.9 3.0 0.0014 18.9 3.0 3.0 2 1 0 2 2 2 1 C1 domain PHD PF00628.29 OQS02767.1 - 0.0065 16.3 16.2 0.18 11.7 3.6 2.6 2 0 0 2 2 2 2 PHD-finger Zf_RING PF16744.5 OQS02767.1 - 0.037 14.1 10.6 0.24 11.6 3.9 2.6 2 0 0 2 2 2 0 KIAA1045 RING finger PHD_2 PF13831.6 OQS02767.1 - 0.078 12.6 9.9 0.43 10.2 1.2 3.1 2 0 0 2 2 2 0 PHD-finger DUF2318 PF10080.9 OQS02767.1 - 7.9 6.7 10.2 1.8 8.7 1.6 2.4 2 0 0 2 2 2 0 Predicted membrane protein (DUF2318) Glyco_hydro_72 PF03198.14 OQS02768.1 - 1.8e-88 296.9 7.6 4.4e-45 154.3 1.1 2.2 2 0 0 2 2 2 2 Glucanosyltransferase MA3 PF02847.17 OQS02768.1 - 1.1e-34 118.8 0.8 2.1e-17 63.1 0.1 2.7 2 0 0 2 2 2 2 MA3 domain LRR_6 PF13516.6 OQS02768.1 - 7e-18 63.1 6.4 0.017 15.1 0.1 7.1 6 0 0 6 6 6 5 Leucine Rich repeat EF-hand_1 PF00036.32 OQS02768.1 - 3.2e-09 35.7 0.2 0.0022 17.4 0.0 2.9 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 OQS02768.1 - 8.1e-07 28.5 0.1 0.0037 17.1 0.0 2.9 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 OQS02768.1 - 2.4e-06 26.8 0.2 0.0048 16.3 0.0 2.8 2 0 0 2 2 2 2 EF hand DUF4476 PF14771.6 OQS02768.1 - 2.7e-06 27.6 0.2 2e-05 24.8 0.2 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF4476) EF-hand_8 PF13833.6 OQS02768.1 - 3.2e-06 26.9 0.5 1.1e-05 25.2 0.2 2.2 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_7 PF13499.6 OQS02768.1 - 1.9e-05 25.0 0.1 9.9e-05 22.7 0.1 2.3 1 0 0 1 1 1 1 EF-hand domain pair DUF2829 PF11195.8 OQS02768.1 - 0.018 15.2 0.0 13 6.1 0.0 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2829) LRR_4 PF12799.7 OQS02768.1 - 0.032 14.6 5.6 0.6 10.6 0.2 4.1 3 0 0 3 3 3 0 Leucine Rich repeats (2 copies) Glyco_hydro_cc PF11790.8 OQS02768.1 - 0.16 11.5 1.5 2.5 7.6 0.4 2.5 2 0 0 2 2 2 0 Glycosyl hydrolase catalytic core zf-C2H2_aberr PF17017.5 OQS02768.1 - 0.22 11.7 3.0 1.6 8.9 0.1 3.3 4 0 0 4 4 3 0 Aberrant zinc-finger AF0941-like PF14591.6 OQS02768.1 - 0.24 12.0 1.0 1.4 9.5 0.1 2.5 2 0 0 2 2 2 0 AF0941-like CHCH PF06747.13 OQS02768.1 - 1.4 9.1 4.3 34 4.7 0.1 3.1 3 0 0 3 3 3 0 CHCH domain LRR_8 PF13855.6 OQS02768.1 - 6.7 6.6 8.0 9.2 6.1 1.1 4.1 4 2 0 4 4 3 0 Leucine rich repeat WD40 PF00400.32 OQS02769.1 - 2.5e-44 148.4 17.2 3.2e-08 34.1 0.5 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OQS02769.1 - 2e-06 28.0 2.2 0.01 16.1 0.1 4.9 2 1 5 7 7 7 2 Anaphase-promoting complex subunit 4 WD40 domain Nucleoporin_N PF08801.11 OQS02769.1 - 0.0013 17.5 0.0 0.25 10.0 0.0 3.6 1 1 1 3 3 3 1 Nup133 N terminal like PQQ_2 PF13360.6 OQS02769.1 - 0.033 13.7 1.2 0.35 10.4 0.1 2.9 3 1 0 3 3 3 0 PQQ-like domain PCRF PF03462.18 OQS02770.1 - 4.7e-50 170.1 0.2 4.7e-50 170.1 0.2 1.5 2 0 0 2 2 2 1 PCRF domain RF-1 PF00472.20 OQS02770.1 - 5.6e-42 142.4 2.5 9.8e-41 138.3 0.0 2.3 2 0 0 2 2 2 1 RF-1 domain DREPP PF05558.12 OQS02770.1 - 0.0013 18.7 0.9 0.0023 17.8 0.9 1.3 1 0 0 1 1 1 1 DREPP plasma membrane polypeptide Ebp2 PF05890.12 OQS02771.1 - 1.9e-65 221.1 39.4 2.5e-65 220.7 39.4 1.1 1 0 0 1 1 1 1 Eukaryotic rRNA processing protein EBP2 Baculo_VP91_N PF08475.10 OQS02771.1 - 0.16 11.7 0.1 0.26 11.0 0.1 1.4 1 0 0 1 1 1 0 Viral capsid protein 91 N-terminal FAD_binding_3 PF01494.19 OQS02772.1 - 2e-07 30.6 0.2 1.1e-06 28.1 0.1 2.3 3 0 0 3 3 3 1 FAD binding domain Pyr_redox_2 PF07992.14 OQS02772.1 - 2.2e-06 27.1 0.0 4.3e-06 26.2 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 OQS02772.1 - 5.4e-05 22.9 0.1 0.00016 21.4 0.1 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 OQS02772.1 - 0.00016 21.0 0.1 0.00035 19.9 0.1 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OQS02772.1 - 0.00026 21.2 0.0 0.0007 19.8 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 OQS02772.1 - 0.00042 20.8 0.1 0.0015 19.0 0.0 2.0 2 0 0 2 2 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.6 OQS02772.1 - 0.00053 20.4 0.0 0.0018 18.7 0.0 1.9 1 0 0 1 1 1 1 Putative NAD(P)-binding HI0933_like PF03486.14 OQS02772.1 - 0.0008 18.2 0.0 0.0014 17.4 0.0 1.4 1 0 0 1 1 1 1 HI0933-like protein UDPG_MGDP_dh_N PF03721.14 OQS02772.1 - 0.0018 17.9 0.0 0.003 17.2 0.0 1.3 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain FAD_binding_2 PF00890.24 OQS02772.1 - 0.002 17.3 0.1 0.0035 16.5 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain TrkA_N PF02254.18 OQS02772.1 - 0.002 18.4 0.0 0.0047 17.2 0.0 1.7 1 0 0 1 1 1 1 TrkA-N domain AlaDh_PNT_C PF01262.21 OQS02772.1 - 0.0023 17.2 0.1 0.0063 15.8 0.0 1.7 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain CUE PF02845.16 OQS02772.1 - 0.007 16.0 0.1 0.016 14.9 0.1 1.6 1 0 0 1 1 1 1 CUE domain Thi4 PF01946.17 OQS02772.1 - 0.032 13.5 0.0 0.057 12.7 0.0 1.3 1 0 0 1 1 1 0 Thi4 family 2-Hacid_dh_C PF02826.19 OQS02772.1 - 0.034 13.5 0.0 0.068 12.5 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Lycopene_cycl PF05834.12 OQS02772.1 - 0.046 12.8 0.0 0.089 11.8 0.0 1.5 1 0 0 1 1 1 0 Lycopene cyclase protein FAD_oxidored PF12831.7 OQS02772.1 - 0.052 12.9 0.2 0.085 12.2 0.2 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase GIDA PF01134.22 OQS02772.1 - 0.1 11.7 0.0 0.54 9.3 0.0 2.2 2 0 0 2 2 2 0 Glucose inhibited division protein A 3HCDH_N PF02737.18 OQS02772.1 - 0.14 12.0 0.0 0.45 10.4 0.0 1.9 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain WW PF00397.26 OQS02773.1 - 5.3e-09 36.0 14.0 1.7e-05 24.8 4.7 3.0 2 0 0 2 2 2 2 WW domain IQ PF00612.27 OQS02773.1 - 5.8e-07 28.8 92.2 0.06 13.2 2.6 13.3 13 0 0 13 13 13 8 IQ calmodulin-binding motif zf-B_box PF00643.24 OQS02773.1 - 0.81 9.9 43.6 0.21 11.7 5.9 3.6 3 0 0 3 3 3 0 B-box zinc finger SRP9-21 PF05486.12 OQS02773.1 - 2 8.8 6.3 2.6 8.5 2.4 3.2 3 0 0 3 3 3 0 Signal recognition particle 9 kDa protein (SRP9) NHL PF01436.21 OQS02774.1 - 7.3e-21 73.1 20.9 2.2e-06 27.4 2.0 6.6 5 1 0 5 5 5 5 NHL repeat SGL PF08450.12 OQS02774.1 - 0.00014 21.5 0.1 0.01 15.5 0.0 3.5 2 1 2 5 5 5 1 SMP-30/Gluconolactonase/LRE-like region DUF5128 PF17170.4 OQS02774.1 - 0.001 18.3 0.1 1.5 7.9 0.0 2.6 2 1 0 2 2 2 2 6-bladed beta-propeller ANAPC4_WD40 PF12894.7 OQS02774.1 - 0.035 14.4 0.0 2.4 8.5 0.0 2.5 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain Band_7 PF01145.25 OQS02775.1 - 1.2e-23 84.0 2.9 1.2e-23 84.0 2.9 2.1 2 1 0 2 2 2 1 SPFH domain / Band 7 family LVIVD PF08309.11 OQS02775.1 - 0.084 12.2 0.1 0.14 11.5 0.1 1.4 1 0 0 1 1 1 0 LVIVD repeat DivIVA PF05103.13 OQS02775.1 - 0.13 12.3 6.8 0.27 11.3 6.8 1.5 1 0 0 1 1 1 0 DivIVA protein V-ATPase_G_2 PF16999.5 OQS02775.1 - 0.21 12.0 6.6 0.14 12.5 4.7 1.7 1 1 0 1 1 1 0 Vacuolar (H+)-ATPase G subunit AAA PF00004.29 OQS02776.1 - 4.6e-10 40.0 0.0 1.5e-09 38.4 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) WW PF00397.26 OQS02776.1 - 6.5e-07 29.3 2.7 6.5e-07 29.3 2.7 2.5 2 0 0 2 2 2 1 WW domain AAA_18 PF13238.6 OQS02776.1 - 1.3e-05 25.8 0.0 5.6e-05 23.7 0.0 2.2 1 0 0 1 1 1 1 AAA domain Rad17 PF03215.15 OQS02776.1 - 3.3e-05 23.9 0.1 0.0025 17.8 0.0 2.6 2 0 0 2 2 2 1 Rad17 P-loop domain RFC1 PF08519.12 OQS02776.1 - 3.5e-05 24.0 0.1 9.6e-05 22.6 0.1 1.8 1 0 0 1 1 1 1 Replication factor RFC1 C terminal domain AAA_22 PF13401.6 OQS02776.1 - 0.0001 22.6 4.9 0.00092 19.5 0.0 3.6 3 1 0 3 3 3 1 AAA domain AAA_14 PF13173.6 OQS02776.1 - 0.00012 22.1 0.0 0.00038 20.5 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 OQS02776.1 - 0.003 17.7 0.0 0.011 15.9 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 OQS02776.1 - 0.0041 17.5 0.1 0.021 15.2 0.0 2.3 2 1 0 2 2 1 1 AAA ATPase domain Zeta_toxin PF06414.12 OQS02776.1 - 0.0052 16.1 0.0 0.013 14.7 0.0 1.6 1 0 0 1 1 1 1 Zeta toxin AAA_5 PF07728.14 OQS02776.1 - 0.0056 16.7 0.0 0.018 15.0 0.0 1.9 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 OQS02776.1 - 0.0092 15.7 0.0 0.02 14.7 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_30 PF13604.6 OQS02776.1 - 0.01 15.6 0.0 0.026 14.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 OQS02776.1 - 0.011 15.4 0.0 0.047 13.3 0.0 2.1 2 0 0 2 2 1 0 AAA domain AAA_23 PF13476.6 OQS02776.1 - 0.031 14.8 0.0 0.031 14.8 0.0 3.5 3 1 0 3 3 2 0 AAA domain AAA_assoc_2 PF16193.5 OQS02776.1 - 0.035 14.4 0.0 0.16 12.3 0.0 2.3 1 0 0 1 1 1 0 AAA C-terminal domain AAA_24 PF13479.6 OQS02776.1 - 0.069 12.9 0.0 0.25 11.0 0.0 1.9 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 OQS02776.1 - 0.11 12.3 0.0 0.26 11.0 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein ABC_tran PF00005.27 OQS02776.1 - 0.59 10.6 0.0 0.59 10.6 0.0 2.9 2 1 0 2 2 1 0 ABC transporter RVT_3 PF13456.6 OQS02777.1 - 1.7e-07 31.1 0.1 4e-06 26.6 0.1 2.3 1 1 0 1 1 1 1 Reverse transcriptase-like RNase_H PF00075.24 OQS02777.1 - 0.00037 20.7 0.1 0.0011 19.1 0.1 1.8 1 1 0 1 1 1 1 RNase H GST_N PF02798.20 OQS02778.1 - 3.1e-07 30.6 0.0 3.8e-07 30.3 0.0 1.1 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 OQS02778.1 - 0.0001 22.6 0.0 0.00013 22.4 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain IMD PF08397.11 OQS02779.1 - 0.014 14.7 0.7 0.027 13.8 0.7 1.5 1 0 0 1 1 1 0 IRSp53/MIM homology domain STIMATE PF12400.8 OQS02779.1 - 0.029 14.9 1.2 0.048 14.2 1.2 1.4 1 0 0 1 1 1 0 STIMATE family DUF3280 PF11684.8 OQS02779.1 - 0.03 14.7 1.0 2.8 8.4 0.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2380) CD52 PF15116.6 OQS02780.1 - 0.031 14.3 0.2 0.13 12.3 0.2 2.1 1 0 0 1 1 1 0 CAMPATH-1 antigen S_4TM PF18159.1 OQS02780.1 - 4.2 6.6 10.9 23 4.2 0.4 3.4 3 0 0 3 3 3 0 SMODS-associating 4TM effector domain Adaptin_N PF01602.20 OQS02781.1 - 0.024 13.2 0.1 0.034 12.7 0.1 1.2 1 0 0 1 1 1 0 Adaptin N terminal region DHHC PF01529.20 OQS02782.1 - 8.6e-35 119.8 17.9 8.6e-35 119.8 17.9 2.1 2 0 0 2 2 2 1 DHHC palmitoyltransferase RHH_5 PF07878.11 OQS02782.1 - 0.075 12.9 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 CopG-like RHH_1 or ribbon-helix-helix domain, RHH_5 ABC_tran PF00005.27 OQS02783.1 - 2.4e-51 173.9 0.0 7.2e-26 91.3 0.0 2.4 2 0 0 2 2 2 2 ABC transporter ABC2_membrane_3 PF12698.7 OQS02783.1 - 4e-47 161.0 68.0 1.3e-29 103.4 20.8 3.2 2 1 0 2 2 2 2 ABC-2 family transporter protein AAA_21 PF13304.6 OQS02783.1 - 9.1e-22 78.2 4.0 3.8e-08 33.5 0.0 4.2 3 1 0 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 OQS02783.1 - 1.4e-05 25.7 1.5 0.0031 18.1 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_15 PF13175.6 OQS02783.1 - 3.3e-05 23.8 0.2 0.2 11.3 0.0 3.0 3 0 0 3 3 3 2 AAA ATPase domain SMC_N PF02463.19 OQS02783.1 - 0.00035 20.1 0.0 1.2 8.5 0.0 3.1 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 OQS02783.1 - 0.005 16.8 1.8 0.01 15.7 0.1 2.2 2 0 0 2 2 2 1 RsgA GTPase AAA_30 PF13604.6 OQS02783.1 - 0.026 14.3 0.5 2.6 7.7 0.2 2.3 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 OQS02783.1 - 0.027 14.6 0.0 4.7 7.3 0.1 2.7 2 0 0 2 2 2 0 50S ribosome-binding GTPase SbcCD_C PF13558.6 OQS02783.1 - 0.032 14.5 0.0 15 5.9 0.0 4.2 3 2 0 3 3 3 0 Putative exonuclease SbcCD, C subunit ABC2_membrane PF01061.24 OQS02783.1 - 0.04 13.3 51.5 0.013 15.0 22.7 5.0 4 1 1 5 5 5 0 ABC-2 type transporter DUF4162 PF13732.6 OQS02783.1 - 0.051 14.3 0.0 2.8 8.7 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4162) AAA_29 PF13555.6 OQS02783.1 - 0.07 12.9 6.5 0.067 12.9 0.6 3.0 3 0 0 3 3 3 0 P-loop containing region of AAA domain SRP54 PF00448.22 OQS02783.1 - 0.38 10.3 3.9 4.8 6.8 0.6 2.3 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain MukB PF04310.12 OQS02783.1 - 2 8.2 3.6 2.9 7.6 0.3 2.2 2 0 0 2 2 2 0 MukB N-terminal Babuvirus_MP PF07234.11 OQS02784.1 - 2.9 8.1 7.0 7.5 6.8 0.4 3.3 3 0 0 3 3 3 0 Movement and RNA silencing protein Kazal_2 PF07648.15 OQS02785.1 - 2.7e-37 126.7 40.7 2.6e-12 46.7 6.8 4.2 4 0 0 4 4 4 4 Kazal-type serine protease inhibitor domain Kazal_1 PF00050.21 OQS02785.1 - 1.1e-35 121.4 35.2 4.9e-10 39.3 6.3 4.2 3 1 1 4 4 4 4 Kazal-type serine protease inhibitor domain DOT1 PF08123.13 OQS02786.1 - 1.4e-12 47.5 0.0 2.3e-12 46.9 0.0 1.3 1 0 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_31 PF13847.6 OQS02786.1 - 0.00019 21.2 0.0 0.00028 20.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OQS02786.1 - 0.0016 19.1 0.0 0.0049 17.5 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_4 PF02390.17 OQS02786.1 - 0.0018 17.8 0.0 0.0032 17.0 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_11 PF08241.12 OQS02786.1 - 0.0052 17.4 0.0 0.014 16.1 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain ORMDL PF04061.14 OQS02786.1 - 0.014 15.2 0.0 0.023 14.5 0.0 1.3 1 0 0 1 1 1 0 ORMDL family Methyltransf_PK PF05891.12 OQS02786.1 - 0.081 12.4 0.0 0.74 9.3 0.0 2.0 2 0 0 2 2 2 0 AdoMet dependent proline di-methyltransferase DUF1843 PF08898.10 OQS02786.1 - 0.11 13.0 0.0 0.27 11.7 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1843) EI24 PF07264.11 OQS02787.1 - 0.00078 19.7 4.3 0.0012 19.1 4.3 1.3 1 0 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) PRA1 PF03208.19 OQS02787.1 - 0.42 10.2 6.3 0.25 11.0 3.9 1.8 1 1 0 1 1 1 0 PRA1 family protein PX PF00787.24 OQS02788.1 - 4.3e-15 55.7 0.3 5.7e-15 55.3 0.3 1.1 1 0 0 1 1 1 1 PX domain Tn916-Xis PF09035.10 OQS02788.1 - 0.16 12.2 0.0 0.3 11.3 0.0 1.4 1 0 0 1 1 1 0 Excisionase from transposon Tn916 zf-C3HC4 PF00097.25 OQS02789.1 - 0.057 13.3 8.0 0.3 11.0 8.2 2.2 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DZR PF12773.7 OQS02789.1 - 0.093 12.8 8.8 0.29 11.2 8.8 1.9 1 0 0 1 1 1 0 Double zinc ribbon FYVE PF01363.21 OQS02789.1 - 0.15 12.2 7.0 0.34 11.1 7.0 1.6 1 0 0 1 1 1 0 FYVE zinc finger zf-C3HC4_3 PF13920.6 OQS02789.1 - 0.18 11.7 11.7 1.1 9.1 11.7 2.2 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) FYVE_2 PF02318.16 OQS02789.1 - 0.32 11.2 5.9 0.7 10.1 5.9 1.5 1 0 0 1 1 1 0 FYVE-type zinc finger IBR PF01485.21 OQS02789.1 - 1.7 9.0 9.8 0.32 11.3 5.6 1.9 2 0 0 2 2 2 0 IBR domain, a half RING-finger domain zf-RING_5 PF14634.6 OQS02789.1 - 3.9 7.5 9.8 16 5.6 9.9 2.0 1 1 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_2 PF13923.6 OQS02789.1 - 6.4 6.7 9.6 2.3 8.1 5.7 2.3 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Homoserine_dh PF00742.19 OQS02791.1 - 2.2e-54 184.0 0.3 4.5e-54 183.0 0.3 1.5 1 0 0 1 1 1 1 Homoserine dehydrogenase NAD_binding_3 PF03447.16 OQS02791.1 - 6e-15 55.9 0.1 1.2e-14 55.0 0.1 1.4 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain ACT PF01842.25 OQS02791.1 - 0.00016 21.4 0.1 0.00035 20.3 0.1 1.7 1 0 0 1 1 1 1 ACT domain Thiol_cytolysin PF01289.19 OQS02791.1 - 0.099 11.5 0.1 0.15 10.9 0.1 1.2 1 0 0 1 1 1 0 Thiol-activated cytolysin UPRTase PF14681.6 OQS02792.1 - 6.2e-65 218.5 0.0 8.4e-65 218.1 0.0 1.1 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.27 OQS02792.1 - 3.7e-05 23.3 0.0 6.1e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain Peptidase_S30 PF01577.16 OQS02792.1 - 0.028 14.0 0.1 0.04 13.5 0.1 1.1 1 0 0 1 1 1 0 Potyvirus P1 protease 2OG-FeII_Oxy_2 PF13532.6 OQS02794.1 - 5.1e-13 49.7 0.0 6.5e-13 49.3 0.0 1.4 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.20 OQS02794.1 - 0.056 13.9 0.1 0.11 13.0 0.1 1.6 1 1 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily Methyltransf_11 PF08241.12 OQS02795.1 - 8.6e-13 48.8 0.0 7.4e-12 45.8 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 OQS02795.1 - 3.7e-10 40.4 0.0 8.1e-10 39.3 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 OQS02795.1 - 1.1e-09 38.0 0.0 1.5e-09 37.6 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.6 OQS02795.1 - 6.9e-09 35.7 0.0 8.3e-09 35.4 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OQS02795.1 - 2.9e-05 24.7 0.0 0.00049 20.8 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Glyco_transf_8 PF01501.20 OQS02796.1 - 6.7e-32 111.0 2.5 1.6e-15 57.3 0.2 2.4 2 0 0 2 2 2 2 Glycosyl transferase family 8 Nucleotid_trans PF03407.16 OQS02796.1 - 2e-05 24.7 2.5 0.079 12.9 0.1 2.4 2 0 0 2 2 2 2 Nucleotide-diphospho-sugar transferase Mannosyl_trans3 PF11051.8 OQS02796.1 - 9.5e-05 21.9 0.4 0.2 11.0 0.0 2.4 2 0 0 2 2 2 2 Mannosyltransferase putative Glyco_transf_21 PF13506.6 OQS02796.1 - 0.012 15.1 1.0 5.7 6.4 0.0 2.8 3 0 0 3 3 3 0 Glycosyl transferase family 21 DUF273 PF03314.14 OQS02796.1 - 0.015 14.8 0.8 6.4 6.3 0.1 2.9 3 0 0 3 3 3 0 Protein of unknown function, DUF273 Glyoxalase_2 PF12681.7 OQS02796.1 - 1.6 8.6 3.9 27 4.7 0.1 2.9 3 0 0 3 3 3 0 Glyoxalase-like domain FKS1_dom1 PF14288.6 OQS02796.1 - 3.1 8.1 11.5 4.4 7.6 1.9 2.9 2 2 0 2 2 2 0 1,3-beta-glucan synthase subunit FKS1, domain-1 Methyltransf_25 PF13649.6 OQS02797.1 - 3.4e-37 127.0 0.0 1e-20 74.2 0.0 3.1 3 1 1 4 4 2 2 Methyltransferase domain Methyltransf_11 PF08241.12 OQS02797.1 - 3.3e-36 123.8 0.0 2.9e-21 75.9 0.0 2.9 3 0 0 3 3 2 2 Methyltransferase domain Methyltransf_31 PF13847.6 OQS02797.1 - 1.6e-29 102.7 0.0 6.8e-21 74.6 0.0 2.4 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_23 PF13489.6 OQS02797.1 - 1.1e-27 96.9 0.0 1.5e-19 70.4 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.12 OQS02797.1 - 2.6e-22 79.4 0.0 5.2e-13 49.6 0.0 2.5 2 0 0 2 2 2 2 Methyltransferase domain CMAS PF02353.20 OQS02797.1 - 2.1e-17 63.3 0.0 8.7e-17 61.3 0.0 1.9 2 1 0 2 2 2 1 Mycolic acid cyclopropane synthetase Ubie_methyltran PF01209.18 OQS02797.1 - 2.2e-14 53.3 0.0 7.1e-11 41.9 0.0 2.3 2 0 0 2 2 2 2 ubiE/COQ5 methyltransferase family Methyltransf_PK PF05891.12 OQS02797.1 - 1.8e-12 47.3 0.0 8.6e-10 38.5 0.0 2.6 3 0 0 3 3 3 2 AdoMet dependent proline di-methyltransferase MTS PF05175.14 OQS02797.1 - 1.9e-08 34.0 0.0 0.00012 21.7 0.0 2.5 2 0 0 2 2 2 2 Methyltransferase small domain NodS PF05401.11 OQS02797.1 - 2e-08 34.1 0.0 1.4e-05 24.8 0.0 2.2 2 0 0 2 2 2 2 Nodulation protein S (NodS) CheR PF01739.18 OQS02797.1 - 3.8e-08 33.0 0.0 0.0045 16.5 0.0 3.4 2 1 1 3 3 3 2 CheR methyltransferase, SAM binding domain TehB PF03848.14 OQS02797.1 - 2.3e-07 30.4 0.0 0.0069 15.8 0.0 2.6 3 0 0 3 3 2 2 Tellurite resistance protein TehB Methyltransf_29 PF03141.16 OQS02797.1 - 4.3e-07 28.9 0.0 7.2e-05 21.5 0.0 2.1 2 0 0 2 2 2 2 Putative S-adenosyl-L-methionine-dependent methyltransferase PCMT PF01135.19 OQS02797.1 - 5.2e-07 29.6 0.0 3.8e-05 23.6 0.0 2.3 2 0 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) TPMT PF05724.11 OQS02797.1 - 6e-07 29.3 0.0 0.00062 19.5 0.0 2.4 2 0 0 2 2 2 2 Thiopurine S-methyltransferase (TPMT) RrnaAD PF00398.20 OQS02797.1 - 8e-07 28.4 0.0 0.00038 19.6 0.0 2.2 2 0 0 2 2 2 2 Ribosomal RNA adenine dimethylase Methyltransf_9 PF08003.11 OQS02797.1 - 2.7e-06 26.5 0.0 0.00084 18.4 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF1698) MetW PF07021.12 OQS02797.1 - 1.8e-05 24.4 0.0 3.3e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW DOT1 PF08123.13 OQS02797.1 - 0.0095 15.5 0.0 0.026 14.1 0.1 1.7 2 0 0 2 2 2 1 Histone methylation protein DOT1 Bin3 PF06859.12 OQS02797.1 - 0.01 16.5 0.0 0.47 11.1 0.0 2.7 2 1 0 2 2 2 0 Bicoid-interacting protein 3 (Bin3) PrmA PF06325.13 OQS02797.1 - 0.013 15.0 0.0 0.037 13.4 0.0 1.7 2 0 0 2 2 2 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_32 PF13679.6 OQS02797.1 - 0.019 15.0 0.0 0.078 13.0 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain Met_10 PF02475.16 OQS02797.1 - 0.034 13.9 0.0 1.9 8.2 0.0 2.3 2 0 0 2 2 2 0 Met-10+ like-protein DUF938 PF06080.12 OQS02797.1 - 0.078 12.7 0.0 10 5.8 0.0 3.0 3 1 0 3 3 2 0 Protein of unknown function (DUF938) DUF1461 PF07314.11 OQS02798.1 - 0.015 15.2 0.6 0.015 15.2 0.6 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1461) DUF2085 PF09858.9 OQS02798.1 - 0.11 13.0 4.1 1.8 9.1 0.3 2.5 2 1 0 2 2 2 0 Predicted membrane protein (DUF2085) Pkinase PF00069.25 OQS02799.1 - 6.1e-49 166.8 0.0 1.1e-48 165.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQS02799.1 - 3e-48 164.4 0.0 4.1e-48 163.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase LRR_6 PF13516.6 OQS02799.1 - 1.6e-09 37.0 8.4 0.27 11.4 0.1 7.5 8 0 0 8 8 7 2 Leucine Rich repeat LRR_4 PF12799.7 OQS02799.1 - 1.8e-09 37.7 33.0 0.00037 20.8 0.3 5.7 4 1 1 5 5 5 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 OQS02799.1 - 1.4e-08 34.3 30.6 0.00026 20.7 6.2 5.5 2 2 6 8 8 8 8 Leucine rich repeat SKG6 PF08693.10 OQS02799.1 - 1.1e-05 24.7 1.8 1.1e-05 24.7 1.8 3.0 3 0 0 3 3 3 2 Transmembrane alpha-helix domain TMEM51 PF15345.6 OQS02799.1 - 0.00023 21.1 0.0 0.0029 17.5 0.1 2.1 2 0 0 2 2 2 1 Transmembrane protein 51 DUF4448 PF14610.6 OQS02799.1 - 0.00044 20.1 0.3 0.071 12.9 0.0 3.0 3 0 0 3 3 3 1 Protein of unknown function (DUF4448) TMEM154 PF15102.6 OQS02799.1 - 0.00051 20.0 1.3 0.0014 18.6 1.3 1.7 1 0 0 1 1 1 1 TMEM154 protein family Adeno_E3_CR2 PF02439.15 OQS02799.1 - 0.00052 19.7 0.6 0.018 14.8 0.3 2.5 2 0 0 2 2 2 1 Adenovirus E3 region protein CR2 EphA2_TM PF14575.6 OQS02799.1 - 0.0012 19.6 0.0 0.13 13.1 0.0 2.6 2 0 0 2 2 2 1 Ephrin type-A receptor 2 transmembrane domain DUF4381 PF14316.6 OQS02799.1 - 0.0021 18.3 0.0 1.4 9.1 0.0 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF4381) MHYT PF03707.16 OQS02799.1 - 0.013 15.6 2.2 4.3 7.6 0.2 2.9 3 0 0 3 3 2 0 Bacterial signalling protein N terminal repeat Mid2 PF04478.12 OQS02799.1 - 0.024 14.5 1.9 0.15 11.9 0.4 2.3 2 0 0 2 2 2 0 Mid2 like cell wall stress sensor Amnionless PF14828.6 OQS02799.1 - 0.026 13.4 0.0 0.062 12.1 0.1 1.5 2 0 0 2 2 2 0 Amnionless Pkinase_fungal PF17667.1 OQS02799.1 - 0.054 12.3 0.3 0.11 11.3 0.3 1.6 1 1 0 1 1 1 0 Fungal protein kinase DUF347 PF03988.12 OQS02799.1 - 0.062 13.5 1.5 6.6 7.0 0.1 2.5 2 0 0 2 2 2 0 Repeat of Unknown Function (DUF347) MGC-24 PF05283.11 OQS02799.1 - 0.062 13.7 7.2 0.22 12.0 7.2 2.0 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin LapA_dom PF06305.11 OQS02799.1 - 0.071 12.9 1.0 2.3 8.1 0.2 2.4 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain RIFIN PF02009.16 OQS02799.1 - 0.082 12.8 0.1 0.17 11.7 0.1 1.5 1 0 0 1 1 1 0 Rifin Gram_pos_anchor PF00746.21 OQS02799.1 - 0.27 11.2 3.6 7.7 6.6 0.2 2.5 2 0 0 2 2 2 0 LPXTG cell wall anchor motif FeoB_associated PF12669.7 OQS02799.1 - 0.38 11.2 3.7 4.7 7.7 0.8 2.5 2 0 0 2 2 2 0 FeoB-associated Cys-rich membrane protein LRR_9 PF14580.6 OQS02799.1 - 0.49 9.9 7.5 9.3 5.7 1.9 3.2 2 1 1 3 3 3 0 Leucine-rich repeat Podoplanin PF05808.11 OQS02799.1 - 0.69 10.0 7.3 0.043 13.9 0.7 2.3 2 0 0 2 2 2 0 Podoplanin Hamartin PF04388.12 OQS02799.1 - 0.95 8.0 3.9 1.4 7.5 3.9 1.1 1 0 0 1 1 1 0 Hamartin protein RSN1_7TM PF02714.15 OQS02800.1 - 2.2e-36 125.6 24.5 2.2e-36 125.6 24.5 1.9 2 0 0 2 2 2 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 OQS02800.1 - 4.7e-30 104.4 0.4 2.4e-29 102.1 0.4 2.3 1 0 0 1 1 1 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 OQS02800.1 - 9.8e-21 74.8 2.7 3.4e-12 46.9 0.1 2.3 1 1 1 2 2 2 2 Cytosolic domain of 10TM putative phosphate transporter Glyco_hydro_12 PF01670.16 OQS02801.1 - 3e-42 145.0 6.3 3.5e-42 144.8 6.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 12 YL1 PF05764.13 OQS02802.1 - 0.0082 16.3 0.6 0.0082 16.3 0.6 1.6 2 0 0 2 2 2 1 YL1 nuclear protein Pkinase PF00069.25 OQS02803.1 - 7.3e-58 196.0 0.3 3e-57 194.0 0.3 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQS02803.1 - 6.8e-32 110.8 0.1 8.7e-32 110.4 0.1 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OQS02803.1 - 5.1e-06 25.5 0.1 6.4e-06 25.2 0.1 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 OQS02803.1 - 0.00029 20.3 0.7 0.00039 19.8 0.7 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Cpn60_TCP1 PF00118.24 OQS02803.1 - 0.00037 19.3 0.1 0.00048 18.9 0.1 1.2 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family YrbL-PhoP_reg PF10707.9 OQS02803.1 - 0.00082 19.0 0.1 0.0016 18.0 0.0 1.6 2 0 0 2 2 2 1 PhoP regulatory network protein YrbL Kinase-like PF14531.6 OQS02803.1 - 0.0014 18.0 0.1 0.041 13.2 0.0 2.1 1 1 1 2 2 2 1 Kinase-like RIO1 PF01163.22 OQS02803.1 - 0.028 14.0 1.2 0.059 13.0 1.2 1.5 1 1 0 1 1 1 0 RIO1 family FTA2 PF13095.6 OQS02803.1 - 0.15 11.7 0.4 0.59 9.7 0.2 1.9 1 1 1 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 TPR_12 PF13424.6 OQS02804.1 - 8.2e-19 67.7 1.9 9.9e-06 25.8 0.0 4.5 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_10 PF13374.6 OQS02804.1 - 7.6e-05 22.4 1.0 2.6 8.0 0.0 5.3 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_2 PF07719.17 OQS02804.1 - 0.00022 21.1 2.8 2.5 8.4 0.1 4.7 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_8 PF13181.6 OQS02804.1 - 0.015 15.5 8.7 11 6.5 0.0 4.6 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_7 PF13176.6 OQS02804.1 - 0.15 12.1 1.6 11 6.3 0.0 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.28 OQS02804.1 - 2.3 8.2 3.9 8.6 6.4 0.0 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF917 PF06032.12 OQS02805.1 - 0.18 10.6 0.0 0.18 10.6 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF917) U-box PF04564.15 OQS02807.1 - 2.5e-17 62.8 0.0 7.6e-17 61.3 0.0 1.9 1 0 0 1 1 1 1 U-box domain zf-Nse PF11789.8 OQS02807.1 - 1.2e-05 25.0 0.1 0.00043 20.0 0.0 2.5 2 0 0 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.6 OQS02807.1 - 0.0095 16.0 0.1 0.18 11.9 0.0 2.6 2 0 0 2 2 2 1 RING-type zinc-finger zf-NOSIP PF15906.5 OQS02807.1 - 0.047 13.8 0.0 0.15 12.2 0.0 1.8 1 0 0 1 1 1 0 Zinc-finger of nitric oxide synthase-interacting protein Actin PF00022.19 OQS02808.1 - 6e-129 430.2 0.0 3.3e-128 427.8 0.0 1.8 1 1 0 1 1 1 1 Actin Pkinase PF00069.25 OQS02809.1 - 3e-59 200.5 0.0 5.1e-58 196.5 0.0 2.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQS02809.1 - 1.9e-32 112.6 0.0 3.9e-31 108.3 0.0 2.4 3 0 0 3 3 3 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OQS02809.1 - 8.3e-05 21.5 0.0 0.00011 21.1 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 OQS02809.1 - 0.0066 15.8 0.1 0.032 13.6 0.0 2.0 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 OQS02809.1 - 0.1 11.9 0.0 0.25 10.6 0.0 1.6 1 0 0 1 1 1 0 Kinase-like TPR_2 PF07719.17 OQS02810.1 - 3.6e-35 117.2 11.6 0.00017 21.4 0.0 10.7 11 0 0 11 11 11 8 Tetratricopeptide repeat TPR_1 PF00515.28 OQS02810.1 - 5.5e-35 117.8 19.8 7.9e-07 28.6 0.4 10.5 11 0 0 11 11 11 7 Tetratricopeptide repeat TPR_8 PF13181.6 OQS02810.1 - 2.3e-26 89.8 5.8 0.022 14.9 0.1 9.2 9 0 0 9 9 9 6 Tetratricopeptide repeat TPR_11 PF13414.6 OQS02810.1 - 2.7e-23 81.4 12.4 4.5e-07 29.4 0.1 9.4 9 1 1 10 10 10 5 TPR repeat TPR_9 PF13371.6 OQS02810.1 - 4.8e-21 74.7 0.8 0.0064 16.6 0.0 5.5 5 0 0 5 5 5 5 Tetratricopeptide repeat TPR_14 PF13428.6 OQS02810.1 - 1.9e-15 56.2 0.2 1.1 10.2 0.0 9.0 5 4 6 11 11 11 1 Tetratricopeptide repeat TPR_12 PF13424.6 OQS02810.1 - 3.8e-15 55.9 3.1 0.041 14.2 0.0 8.0 8 1 1 9 9 8 4 Tetratricopeptide repeat TPR_16 PF13432.6 OQS02810.1 - 8.8e-14 51.9 0.5 2.2e-05 25.0 0.1 5.6 4 2 2 6 6 6 3 Tetratricopeptide repeat TPR_15 PF13429.6 OQS02810.1 - 8.9e-11 41.5 0.8 0.057 12.6 0.1 5.7 5 1 0 5 5 5 2 Tetratricopeptide repeat TPR_7 PF13176.6 OQS02810.1 - 4.8e-10 38.7 4.9 0.66 10.1 0.0 6.7 8 0 0 8 8 5 2 Tetratricopeptide repeat TPR_19 PF14559.6 OQS02810.1 - 1.3e-09 38.5 2.8 0.18 12.3 0.0 6.5 6 1 1 7 7 6 2 Tetratricopeptide repeat ANAPC3 PF12895.7 OQS02810.1 - 3.3e-07 30.4 7.8 0.74 10.1 0.0 5.2 5 0 0 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.6 OQS02810.1 - 9.5e-07 28.8 6.7 1 9.9 0.0 8.5 9 1 0 9 9 9 1 Tetratricopeptide repeat TPR_21 PF09976.9 OQS02810.1 - 3.5e-06 26.9 3.1 0.26 11.0 0.1 3.9 3 1 1 4 4 4 2 Tetratricopeptide repeat-like domain TPR_10 PF13374.6 OQS02810.1 - 7.4e-05 22.5 4.6 0.33 10.9 0.1 5.7 7 0 0 7 7 6 1 Tetratricopeptide repeat TPR_6 PF13174.6 OQS02810.1 - 0.00047 20.6 8.3 2.7 8.8 0.1 6.9 8 0 0 8 8 6 1 Tetratricopeptide repeat Coatomer_E PF04733.14 OQS02810.1 - 0.00066 19.2 0.5 1.6 8.1 0.0 3.3 3 1 1 4 4 3 2 Coatomer epsilon subunit SRP_TPR_like PF17004.5 OQS02810.1 - 0.0014 18.6 1.5 0.22 11.6 0.1 3.9 3 1 0 4 4 4 1 Putative TPR-like repeat DUF3856 PF12968.7 OQS02810.1 - 0.0017 18.4 4.3 3.3 7.8 0.2 4.6 3 1 1 4 4 4 1 Domain of Unknown Function (DUF3856) Fis1_TPR_C PF14853.6 OQS02810.1 - 0.0026 17.8 2.9 5.4 7.2 0.1 5.0 5 0 0 5 5 4 1 Fis1 C-terminal tetratricopeptide repeat SHNi-TPR PF10516.9 OQS02810.1 - 0.0084 15.5 0.1 1.1 8.8 0.1 3.5 3 0 0 3 3 3 1 SHNi-TPR TPR_MalT PF17874.1 OQS02810.1 - 0.027 13.9 0.0 5.4 6.3 0.0 2.8 3 0 0 3 3 3 0 MalT-like TPR region NARP1 PF12569.8 OQS02810.1 - 0.034 13.1 7.3 1.6 7.5 0.0 4.6 4 1 0 5 5 5 0 NMDA receptor-regulated protein 1 DUF2333 PF10095.9 OQS02810.1 - 0.043 12.8 0.2 3.5 6.5 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2333) ANAPC5 PF12862.7 OQS02810.1 - 0.16 12.0 1.6 15 5.7 0.1 3.7 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 5 TPR_4 PF07721.14 OQS02810.1 - 0.19 12.5 0.0 14 6.7 0.0 3.4 4 0 0 4 4 2 0 Tetratricopeptide repeat PPR PF01535.20 OQS02810.1 - 0.3 11.4 1.4 49 4.5 0.0 3.7 4 0 0 4 4 3 0 PPR repeat RPN7 PF10602.9 OQS02810.1 - 0.74 9.5 6.7 6.7 6.4 0.2 3.8 3 1 2 5 5 5 0 26S proteasome subunit RPN7 MIT PF04212.18 OQS02810.1 - 1.4 9.0 4.1 18 5.5 0.1 4.6 6 0 0 6 6 5 0 MIT (microtubule interacting and transport) domain SOG2 PF10428.9 OQS02811.1 - 2 7.5 12.0 2.3 7.3 12.0 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Gram_pos_anchor PF00746.21 OQS02811.1 - 4.8 7.2 6.0 3.9 7.5 0.3 2.6 2 0 0 2 2 2 0 LPXTG cell wall anchor motif PAN_1 PF00024.26 OQS02812.1 - 3.3e-10 39.8 13.6 0.02 14.8 0.0 5.4 2 1 3 5 5 5 4 PAN domain PIG-L PF02585.17 OQS02812.1 - 7.4e-05 23.4 0.0 0.00021 21.9 0.0 1.8 1 0 0 1 1 1 1 GlcNAc-PI de-N-acetylase PX PF00787.24 OQS02812.1 - 0.0056 16.6 0.0 0.014 15.4 0.0 1.7 1 0 0 1 1 1 1 PX domain PAN_3 PF08277.12 OQS02812.1 - 1 9.2 10.6 0.72 9.7 0.3 3.7 4 0 0 4 4 4 0 PAN-like domain LRR_6 PF13516.6 OQS02813.1 - 8.4e-09 34.8 22.5 0.00076 19.3 0.1 6.4 8 0 0 8 8 8 4 Leucine Rich repeat p25-alpha PF05517.12 OQS02813.1 - 0.0034 17.6 0.1 0.027 14.6 0.0 2.3 2 0 0 2 2 2 1 p25-alpha LRR_4 PF12799.7 OQS02813.1 - 0.018 15.4 3.2 0.018 15.4 3.2 4.6 2 1 2 5 5 5 0 Leucine Rich repeats (2 copies) AbiJ_NTD4 PF18863.1 OQS02813.1 - 0.15 12.5 1.7 2.2 8.7 0.0 3.1 3 0 0 3 3 3 0 AbiJ N-terminal domain 4 FumaraseC_C PF10415.9 OQS02813.1 - 0.16 12.4 0.0 0.71 10.3 0.0 2.1 2 0 0 2 2 2 0 Fumarase C C-terminus LRR_1 PF00560.33 OQS02813.1 - 0.53 11.0 18.1 8.9 7.3 0.1 6.0 7 0 0 7 7 7 0 Leucine Rich Repeat LRR_8 PF13855.6 OQS02813.1 - 0.8 9.5 21.5 0.065 13.0 7.0 4.5 3 1 3 6 6 6 0 Leucine rich repeat DIM1 PF02966.16 OQS02814.1 - 6.5e-38 129.5 1.9 7.8e-38 129.3 1.9 1.0 1 0 0 1 1 1 1 Mitosis protein DIM1 Thioredoxin PF00085.20 OQS02814.1 - 0.0018 18.3 0.0 0.0023 17.9 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin SPRY PF00622.28 OQS02814.1 - 0.033 14.3 0.0 0.05 13.7 0.0 1.3 1 0 0 1 1 1 0 SPRY domain Vma12 PF11712.8 OQS02815.1 - 0.045 13.8 0.1 0.045 13.8 0.1 1.1 1 0 0 1 1 1 0 Endoplasmic reticulum-based factor for assembly of V-ATPase Cnd2 PF05786.14 OQS02816.1 - 1.9e-97 327.8 32.6 7.4e-70 236.6 25.3 2.6 1 1 1 2 2 2 2 Condensin complex subunit 2 CNDH2_N PF06278.11 OQS02816.1 - 0.0016 18.6 0.4 0.0016 18.6 0.4 2.7 3 0 0 3 3 3 1 Condensin II complex subunit CAP-H2 or CNDH2, N-terminal Dishevelled PF02377.15 OQS02816.1 - 3.5 8.1 15.0 0.71 10.3 9.7 2.4 2 0 0 2 2 2 0 Dishevelled specific domain FYVE PF01363.21 OQS02817.1 - 1.2e-12 47.7 12.1 2.1e-12 47.0 12.1 1.3 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.16 OQS02817.1 - 0.0026 18.0 5.6 0.0052 17.0 5.6 1.4 1 0 0 1 1 1 1 FYVE-type zinc finger Siva PF05458.12 OQS02817.1 - 0.065 12.9 1.4 0.12 12.1 1.4 1.3 1 0 0 1 1 1 0 Cd27 binding protein (Siva) C6_DPF PF10170.9 OQS02817.1 - 4.9 7.6 7.6 3.7 8.0 4.7 2.2 2 0 0 2 2 2 0 Cysteine-rich domain Skp1_POZ PF03931.15 OQS02818.1 - 8.3e-18 64.3 0.1 2e-17 63.1 0.1 1.6 1 0 0 1 1 1 1 Skp1 family, tetramerisation domain Skp1 PF01466.19 OQS02818.1 - 1.3e-17 63.6 0.0 2.6e-17 62.6 0.0 1.5 1 0 0 1 1 1 1 Skp1 family, dimerisation domain BTB PF00651.31 OQS02818.1 - 0.038 14.2 0.2 0.39 11.0 0.2 2.0 1 1 0 1 1 1 0 BTB/POZ domain C2 PF00168.30 OQS02819.1 - 4.4e-16 59.0 0.1 1.2e-15 57.6 0.1 1.8 1 0 0 1 1 1 1 C2 domain PH PF00169.29 OQS02819.1 - 1.1e-13 51.6 0.0 3.4e-13 50.0 0.0 1.9 1 0 0 1 1 1 1 PH domain PDZ_6 PF17820.1 OQS02819.1 - 2.3e-12 46.5 0.0 1.1e-06 28.4 0.0 2.9 2 0 0 2 2 2 2 PDZ domain PDZ PF00595.24 OQS02819.1 - 2.6e-09 37.3 0.8 0.0036 17.6 0.0 3.4 3 0 0 3 3 3 2 PDZ domain PH_11 PF15413.6 OQS02819.1 - 9e-08 32.5 0.0 4.4e-07 30.3 0.0 2.3 1 0 0 1 1 1 1 Pleckstrin homology domain DUF4300 PF14133.6 OQS02819.1 - 0.0024 17.6 5.5 0.077 12.7 0.6 3.1 2 0 0 2 2 2 2 Domain of unknown function (DUF4300) PDZ_2 PF13180.6 OQS02819.1 - 0.0037 17.5 0.2 0.034 14.5 0.0 2.6 2 0 0 2 2 2 1 PDZ domain Speriolin_C PF15059.6 OQS02819.1 - 0.3 11.2 2.9 0.39 10.8 0.6 2.4 2 0 0 2 2 2 0 Speriolin C-terminus Shugoshin_N PF07558.11 OQS02819.1 - 0.55 10.2 10.9 2.2 8.2 0.9 3.6 3 0 0 3 3 3 0 Shugoshin N-terminal coiled-coil region WD40_alt PF14077.6 OQS02819.1 - 0.74 9.7 2.7 11 5.9 0.2 3.0 2 0 0 2 2 2 0 Alternative WD40 repeat motif HU-CCDC81_bac_2 PF18175.1 OQS02819.1 - 5.6 6.9 5.6 26 4.8 0.2 3.9 4 0 0 4 4 3 0 CCDC81-like prokaryotic HU domain 2 DUF365 PF04033.12 OQS02819.1 - 6.8 7.0 6.0 25 5.2 1.1 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF365) Vps16_N PF04841.13 OQS02820.1 - 6.5e-64 216.2 0.0 1.3e-63 215.2 0.0 1.4 1 0 0 1 1 1 1 Vps16, N-terminal region Vps16_C PF04840.12 OQS02820.1 - 1.3e-52 178.9 7.3 3.9e-52 177.3 5.9 2.0 2 0 0 2 2 2 1 Vps16, C-terminal region ANAPC4_WD40 PF12894.7 OQS02820.1 - 0.00042 20.6 0.1 0.043 14.1 0.0 3.2 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain PHD PF00628.29 OQS02821.1 - 2.8e-05 23.9 9.7 2.8e-05 23.9 9.7 2.0 2 0 0 2 2 2 1 PHD-finger zf-C2H2_3 PF13878.6 OQS02821.1 - 0.017 14.9 0.2 0.051 13.4 0.2 1.7 1 0 0 1 1 1 0 zinc-finger of acetyl-transferase ESCO Prok-RING_1 PF14446.6 OQS02821.1 - 0.027 14.4 4.2 0.027 14.4 4.2 2.0 2 0 0 2 2 1 0 Prokaryotic RING finger family 1 VIR_N PF15912.5 OQS02821.1 - 0.14 11.7 6.4 0.21 11.2 6.4 1.3 1 0 0 1 1 1 0 Virilizer, N-terminal GATA PF00320.27 OQS02821.1 - 0.14 11.7 0.2 0.14 11.7 0.2 2.4 2 0 0 2 2 2 0 GATA zinc finger C1_1 PF00130.22 OQS02821.1 - 0.15 11.9 5.5 0.077 12.9 2.4 2.0 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Ndc1_Nup PF09531.10 OQS02821.1 - 0.66 8.6 2.5 0.78 8.4 2.5 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup XAP5 PF04921.14 OQS02821.1 - 0.89 9.3 10.4 2 8.2 10.4 1.5 1 0 0 1 1 1 0 XAP5, circadian clock regulator NST1 PF13945.6 OQS02821.1 - 1.4 9.0 15.0 3.2 7.8 15.0 1.5 1 0 0 1 1 1 0 Salt tolerance down-regulator DUF4614 PF15391.6 OQS02821.1 - 4.8 7.1 10.6 10 6.1 10.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) CDC45 PF02724.14 OQS02821.1 - 6.8 4.9 11.3 1.9 6.7 8.3 1.5 2 0 0 2 2 2 0 CDC45-like protein zf-piccolo PF05715.13 OQS02821.1 - 7.3 6.8 12.3 2.3 8.5 3.9 3.1 2 1 0 2 2 2 0 Piccolo Zn-finger SPT6_acidic PF14632.6 OQS02821.1 - 7.5 7.2 16.0 0.93 10.1 6.3 3.4 3 0 0 3 3 3 0 Acidic N-terminal SPT6 eIF3_subunit PF08597.10 OQS02821.1 - 9.2 6.1 19.6 30 4.4 19.7 1.8 1 1 0 1 1 1 0 Translation initiation factor eIF3 subunit Presenilin PF01080.17 OQS02821.1 - 9.5 4.9 7.4 14 4.3 7.4 1.1 1 0 0 1 1 1 0 Presenilin Kinesin PF00225.23 OQS02822.1 - 7.9e-118 393.2 0.1 7.9e-118 393.2 0.1 1.8 2 0 0 2 2 2 1 Kinesin motor domain CoaE PF01121.20 OQS02822.1 - 5.6e-52 176.0 3.8 1.2e-51 174.9 0.5 2.4 2 0 0 2 2 2 1 Dephospho-CoA kinase Microtub_bd PF16796.5 OQS02822.1 - 2.1e-27 95.9 0.3 6.6e-27 94.3 0.0 2.0 2 0 0 2 2 2 1 Microtubule binding AAA_28 PF13521.6 OQS02822.1 - 4.2e-05 23.8 0.1 4.2e-05 23.8 0.1 3.7 5 0 0 5 5 5 1 AAA domain AAA_33 PF13671.6 OQS02822.1 - 8.9e-05 22.7 0.0 0.021 15.0 0.0 4.1 3 1 0 3 3 3 1 AAA domain AAA_18 PF13238.6 OQS02822.1 - 0.00016 22.2 15.6 0.0011 19.5 0.1 4.9 3 2 2 5 5 5 1 AAA domain AAA_22 PF13401.6 OQS02822.1 - 0.075 13.3 0.6 7 6.9 0.0 3.3 3 0 0 3 3 3 0 AAA domain AAA_16 PF13191.6 OQS02822.1 - 0.57 10.6 12.4 19 5.6 0.0 4.9 4 1 0 4 4 4 0 AAA ATPase domain CHDCT2 PF08074.11 OQS02822.1 - 5.1 7.2 18.2 0.065 13.4 8.3 2.6 1 1 1 2 2 2 0 CHDCT2 (NUC038) domain Kinesin_assoc PF16183.5 OQS02822.1 - 9.9 6.3 16.2 1.4e+02 2.5 16.2 2.7 1 1 0 1 1 1 0 Kinesin-associated Solute_trans_a PF03619.16 OQS02823.1 - 1e-93 313.7 14.5 1.2e-93 313.5 14.5 1.0 1 0 0 1 1 1 1 Organic solute transporter Ostalpha Pox_A_type_inc PF04508.12 OQS02824.1 - 1.6 8.7 7.7 0.28 11.1 1.2 3.3 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat Skp1 PF01466.19 OQS02826.1 - 6.1e-31 106.3 2.6 1.9e-15 56.7 0.3 2.4 2 0 0 2 2 2 2 Skp1 family, dimerisation domain Skp1_POZ PF03931.15 OQS02826.1 - 1.7e-10 40.9 0.0 2.1e-07 31.0 0.0 2.6 2 0 0 2 2 2 2 Skp1 family, tetramerisation domain Herpes_U15 PF05613.11 OQS02826.1 - 0.086 13.6 0.0 26 5.6 0.0 2.6 2 0 0 2 2 2 0 Human herpesvirus U15 protein TPR_12 PF13424.6 OQS02827.1 - 0.019 15.3 2.7 0.12 12.7 1.5 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat Anoctamin PF04547.12 OQS02828.1 - 8.4e-115 384.2 27.4 1e-114 383.9 27.4 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel Adeno_E3_CR2 PF02439.15 OQS02828.1 - 0.072 12.9 4.2 0.26 11.1 4.2 1.9 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Anoct_dimer PF16178.5 OQS02828.1 - 0.081 12.6 0.3 0.39 10.4 0.1 2.0 1 1 1 2 2 2 0 Dimerisation domain of Ca+-activated chloride-channel, anoctamin SecE PF00584.20 OQS02828.1 - 0.1 12.5 2.2 0.14 12.1 0.6 2.0 2 0 0 2 2 2 0 SecE/Sec61-gamma subunits of protein translocation complex Pro-kuma_activ PF09286.11 OQS02829.1 - 1.4e-12 48.1 0.1 1e-11 45.3 0.1 2.0 2 0 0 2 2 2 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 OQS02829.1 - 5.1e-07 29.3 0.1 8.8e-07 28.5 0.1 1.3 1 0 0 1 1 1 1 Subtilase family Peptidase_C28 PF05408.11 OQS02829.1 - 0.076 12.7 0.0 0.22 11.2 0.0 1.7 1 0 0 1 1 1 0 Foot-and-mouth virus L-proteinase Ank_2 PF12796.7 OQS02830.1 - 7.9e-16 58.4 3.9 5.4e-08 33.3 0.2 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQS02830.1 - 1.3e-09 38.4 3.8 1.3e-07 32.0 0.4 2.3 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQS02830.1 - 4.5e-06 26.6 1.1 0.0095 16.4 0.1 3.3 2 1 1 3 3 3 1 Ankyrin repeat Ank_5 PF13857.6 OQS02830.1 - 7.9e-06 26.0 2.0 0.0017 18.6 0.1 3.0 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 OQS02830.1 - 5.1e-05 23.5 0.3 0.12 12.8 0.0 3.3 3 0 0 3 3 3 2 Ankyrin repeat Ank_2 PF12796.7 OQS02831.1 - 9.2e-13 48.6 0.9 4.2e-06 27.2 0.0 3.0 1 1 2 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQS02831.1 - 6.5e-10 39.3 10.4 1.6e-05 25.4 0.5 3.1 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQS02831.1 - 2e-05 24.6 0.4 4.4 8.2 0.0 4.5 3 1 1 4 4 4 1 Ankyrin repeat Ank_5 PF13857.6 OQS02831.1 - 0.0018 18.5 1.0 1.1 9.7 0.0 3.4 1 1 3 4 4 4 2 Ankyrin repeats (many copies) DUF1843 PF08898.10 OQS02831.1 - 0.021 15.3 0.0 0.078 13.5 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1843) PCI PF01399.27 OQS02832.1 - 1.2e-11 45.1 0.0 2.4e-11 44.1 0.0 1.5 1 0 0 1 1 1 1 PCI domain COX5A PF02284.16 OQS02832.1 - 0.11 12.5 0.1 1.1 9.3 0.0 2.3 2 0 0 2 2 2 0 Cytochrome c oxidase subunit Va cNMP_binding PF00027.29 OQS02833.1 - 7.1e-16 58.1 0.0 1.7e-15 56.9 0.0 1.7 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Ank_2 PF12796.7 OQS02833.1 - 4.1e-14 52.9 9.5 5.6e-12 46.1 1.1 3.3 2 1 2 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQS02833.1 - 1.2e-07 32.1 4.2 0.28 11.8 0.0 3.9 3 1 0 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 OQS02833.1 - 2.1e-06 27.9 4.9 0.07 13.5 0.2 4.4 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQS02833.1 - 0.00042 20.5 0.5 1.3 9.8 0.0 4.3 3 1 1 4 4 4 1 Ankyrin repeat Ank PF00023.30 OQS02833.1 - 0.022 15.2 1.1 11 6.7 0.0 4.0 1 1 2 3 3 3 0 Ankyrin repeat EamA PF00892.20 OQS02834.1 - 7.2e-20 71.6 80.8 4.8e-07 30.0 19.6 4.2 4 0 0 4 4 4 4 EamA-like transporter family Motile_Sperm PF00635.26 OQS02835.1 - 4.8e-17 61.8 0.0 1.2e-07 31.5 0.0 3.3 3 0 0 3 3 3 3 MSP (Major sperm protein) domain ASH PF15780.5 OQS02835.1 - 0.024 14.8 0.0 3.5 7.9 0.0 2.7 2 1 0 2 2 2 0 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin Semialdhyde_dhC PF02774.18 OQS02836.1 - 3.7e-48 164.0 0.0 5.2e-48 163.6 0.0 1.2 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, dimerisation domain Semialdhyde_dh PF01118.24 OQS02836.1 - 2e-28 99.3 0.1 3.9e-28 98.3 0.1 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Gp_dh_C PF02800.20 OQS02836.1 - 0.0017 17.9 0.1 0.0059 16.2 0.0 1.9 2 0 0 2 2 2 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain F420_oxidored PF03807.17 OQS02836.1 - 0.0029 18.2 0.2 0.0055 17.3 0.2 1.4 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent DXP_reductoisom PF02670.16 OQS02836.1 - 0.026 15.2 0.6 0.3 11.8 0.2 2.3 1 1 1 2 2 2 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase DapB_N PF01113.20 OQS02836.1 - 0.043 14.0 0.1 0.084 13.0 0.1 1.7 1 1 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Ldh_1_N PF00056.23 OQS02836.1 - 0.078 13.1 0.0 0.13 12.3 0.0 1.4 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain SPRY PF00622.28 OQS02837.1 - 3.3e-16 59.5 0.9 1.1e-08 35.3 0.1 2.5 2 0 0 2 2 2 2 SPRY domain F-box PF00646.33 OQS02837.1 - 5e-09 35.8 1.4 0.00032 20.5 0.2 2.6 2 0 0 2 2 2 2 F-box domain F-box-like PF12937.7 OQS02837.1 - 4e-08 33.0 8.6 0.00054 19.8 1.9 2.7 2 0 0 2 2 2 2 F-box-like Pkinase PF00069.25 OQS02838.1 - 5.4e-60 203.0 0.0 7.8e-60 202.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQS02838.1 - 2e-27 96.1 0.0 3e-27 95.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PH PF00169.29 OQS02838.1 - 3.3e-08 34.0 0.2 8.6e-08 32.6 0.1 1.8 2 0 0 2 2 2 1 PH domain Kinase-like PF14531.6 OQS02838.1 - 1.3e-07 31.2 0.0 4.2e-06 26.3 0.0 2.4 2 0 0 2 2 2 1 Kinase-like PH_11 PF15413.6 OQS02838.1 - 9.6e-05 22.8 1.2 0.00073 19.9 1.2 2.3 1 1 0 1 1 1 1 Pleckstrin homology domain APH PF01636.23 OQS02838.1 - 0.00074 19.5 0.1 0.0041 17.1 0.1 1.9 1 1 1 2 2 2 1 Phosphotransferase enzyme family FTA2 PF13095.6 OQS02838.1 - 0.026 14.1 0.1 7.4 6.1 0.0 2.5 2 1 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Haspin_kinase PF12330.8 OQS02838.1 - 0.052 12.5 0.4 0.17 10.8 0.0 1.8 2 0 0 2 2 2 0 Haspin like kinase domain SUIM_assoc PF16619.5 OQS02838.1 - 0.076 13.1 0.1 0.17 12.0 0.1 1.5 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 Seadorna_VP7 PF07387.11 OQS02838.1 - 0.11 11.5 0.1 0.19 10.7 0.1 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 Axin_b-cat_bind PF08833.10 OQS02838.1 - 0.13 12.4 0.1 3 8.0 0.0 2.8 2 0 0 2 2 2 0 Axin beta-catenin binding domain LRR_4 PF12799.7 OQS02839.1 - 1.3e-20 73.1 35.1 8.9e-07 29.1 5.0 5.9 3 2 3 7 7 7 6 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 OQS02839.1 - 2.2e-12 46.8 10.2 1e-05 25.1 0.6 2.9 2 1 0 2 2 2 2 Leucine-rich repeat LRR_8 PF13855.6 OQS02839.1 - 2.9e-12 46.1 25.9 0.00011 21.8 0.9 4.5 2 1 2 4 4 4 4 Leucine rich repeat Hemerythrin PF01814.23 OQS02839.1 - 3.6e-06 27.6 2.8 1.3e-05 25.8 2.8 2.0 1 1 0 1 1 1 1 Hemerythrin HHE cation binding domain RHH_1 PF01402.21 OQS02839.1 - 0.13 12.2 0.1 0.5 10.4 0.0 2.1 2 0 0 2 2 2 0 Ribbon-helix-helix protein, copG family LRR_1 PF00560.33 OQS02839.1 - 0.35 11.6 32.2 6.2 7.8 0.1 7.8 7 1 0 7 7 7 0 Leucine Rich Repeat LRR_2 PF07723.13 OQS02839.1 - 1.8 9.4 8.4 24 5.8 0.1 4.8 4 1 0 4 4 4 0 Leucine Rich Repeat NAD_binding_8 PF13450.6 OQS02840.1 - 1.2e-10 41.5 0.1 3.6e-10 39.9 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 OQS02840.1 - 1.6e-10 41.1 4.3 2.3e-05 24.2 1.3 2.9 3 0 0 3 3 3 2 FAD dependent oxidoreductase FAD_oxidored PF12831.7 OQS02840.1 - 4.8e-09 36.1 0.0 7.2e-07 28.9 0.0 2.1 2 0 0 2 2 2 2 FAD dependent oxidoreductase Amino_oxidase PF01593.24 OQS02840.1 - 5.6e-09 35.8 0.1 0.003 16.9 0.0 2.9 3 0 0 3 3 3 2 Flavin containing amine oxidoreductase FAD_binding_2 PF00890.24 OQS02840.1 - 3.4e-08 33.0 0.2 1.1e-06 28.0 0.0 2.2 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.14 OQS02840.1 - 6.4e-07 28.9 0.0 0.00059 19.1 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 OQS02840.1 - 9.3e-06 26.1 1.6 0.015 15.9 0.3 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 OQS02840.1 - 4.6e-05 22.8 0.1 7.1e-05 22.2 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 OQS02840.1 - 5.1e-05 22.6 1.6 8.3e-05 21.9 0.2 1.8 2 0 0 2 2 2 1 Thi4 family HI0933_like PF03486.14 OQS02840.1 - 7.3e-05 21.6 1.1 0.0013 17.6 0.5 2.1 2 0 0 2 2 2 1 HI0933-like protein Trp_halogenase PF04820.14 OQS02840.1 - 0.00019 20.4 0.6 0.025 13.4 0.1 2.1 2 0 0 2 2 2 2 Tryptophan halogenase GIDA PF01134.22 OQS02840.1 - 0.0047 16.0 3.9 0.015 14.4 1.6 2.2 2 0 0 2 2 2 1 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 OQS02840.1 - 0.048 12.9 0.9 0.091 12.0 0.9 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase MCRA PF06100.11 OQS02840.1 - 0.054 12.3 0.1 0.088 11.6 0.1 1.3 1 0 0 1 1 1 0 MCRA family Smg4_UPF3 PF03467.15 OQS02841.1 - 1.8e-19 70.4 0.2 4.1e-19 69.3 0.2 1.6 1 1 0 1 1 1 1 Smg-4/UPF3 family DUF5427 PF10310.9 OQS02841.1 - 1.1 8.1 5.6 1.6 7.6 5.6 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5427) Syntaxin_2 PF14523.6 OQS02842.1 - 3.8e-11 43.3 3.4 4.4e-09 36.6 0.2 2.9 2 0 0 2 2 2 2 Syntaxin-like protein PH PF00169.29 OQS02842.1 - 0.06 13.9 0.4 0.31 11.6 0.4 2.3 1 0 0 1 1 1 0 PH domain Laminin_II PF06009.12 OQS02842.1 - 0.097 12.7 7.5 0.79 9.7 0.6 2.6 2 0 0 2 2 2 0 Laminin Domain II TACC_C PF05010.14 OQS02842.1 - 0.45 10.3 8.8 0.083 12.7 2.5 2.5 1 1 1 2 2 2 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal Ank_2 PF12796.7 OQS02843.1 - 5.3e-67 222.4 26.5 1e-14 54.8 0.5 6.8 2 1 6 8 8 8 7 Ankyrin repeats (3 copies) Pkinase PF00069.25 OQS02843.1 - 3.6e-47 160.9 0.0 7.2e-47 160.0 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Ank_5 PF13857.6 OQS02843.1 - 4.3e-44 148.0 18.7 6.5e-10 39.1 0.1 9.6 4 3 4 9 9 9 8 Ankyrin repeats (many copies) Ank PF00023.30 OQS02843.1 - 8.1e-43 143.1 23.9 6.1e-07 29.6 0.1 12.6 12 0 0 12 12 12 8 Ankyrin repeat Pkinase_Tyr PF07714.17 OQS02843.1 - 5.9e-42 143.7 0.0 9.4e-42 143.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Ank_4 PF13637.6 OQS02843.1 - 1.9e-40 136.7 15.9 4.8e-09 36.6 0.3 9.1 5 3 6 11 11 10 9 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQS02843.1 - 9.2e-39 127.0 11.9 9.5e-05 22.5 0.0 12.1 12 0 0 12 12 12 9 Ankyrin repeat Pkinase_fungal PF17667.1 OQS02843.1 - 9.2e-05 21.4 0.0 0.0002 20.3 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase DZR PF12773.7 OQS02843.1 - 0.0011 18.9 6.3 0.0023 17.9 6.3 1.6 1 0 0 1 1 1 1 Double zinc ribbon Kdo PF06293.14 OQS02843.1 - 0.0089 15.4 0.0 0.015 14.6 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 OQS02843.1 - 0.014 14.7 0.0 0.028 13.7 0.0 1.4 1 0 0 1 1 1 0 Kinase-like APH PF01636.23 OQS02843.1 - 0.033 14.1 0.0 0.057 13.3 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family zinc-ribbon_6 PF10005.9 OQS02843.1 - 0.13 12.9 3.4 0.13 12.9 0.7 2.3 2 0 0 2 2 2 0 zinc-ribbon domain zf-RanBP PF00641.18 OQS02843.1 - 0.25 10.7 11.1 2.2 7.7 2.5 2.5 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others Cytochrom_c3_2 PF14537.6 OQS02843.1 - 0.44 11.1 2.3 1.2 9.6 2.3 1.8 1 0 0 1 1 1 0 Cytochrome c3 zf-C4pol PF14260.6 OQS02843.1 - 3 8.4 5.7 11 6.5 5.7 2.0 1 0 0 1 1 1 0 C4-type zinc-finger of DNA polymerase delta FYVE PF01363.21 OQS02844.1 - 1.3e-06 28.4 13.0 1.3e-06 28.4 13.0 2.3 2 0 0 2 2 2 1 FYVE zinc finger FYVE_2 PF02318.16 OQS02844.1 - 1.8e-05 24.9 7.4 1.8e-05 24.9 7.4 1.9 2 0 0 2 2 2 1 FYVE-type zinc finger zf-C3HC4_3 PF13920.6 OQS02844.1 - 0.014 15.2 8.6 0.47 10.4 4.4 2.7 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) Peptidase_C101 PF16218.5 OQS02844.1 - 0.028 13.7 0.1 0.052 12.8 0.1 1.4 1 0 0 1 1 1 0 Peptidase family C101 Baculo_PEP_C PF04513.12 OQS02844.1 - 0.13 12.3 0.5 0.22 11.6 0.5 1.3 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus zf-RING_2 PF13639.6 OQS02844.1 - 0.5 10.8 16.6 0.041 14.2 11.3 2.0 2 0 0 2 2 2 0 Ring finger domain PolC_DP2 PF03833.13 OQS02844.1 - 2 6.1 7.4 2.9 5.6 7.4 1.2 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 Herpes_glycoH_C PF17488.2 OQS02844.1 - 2.7 7.8 8.3 0.68 9.7 4.6 1.9 2 1 0 2 2 2 0 Herpesvirus glycoprotein H C-terminal domain zf-HIT PF04438.16 OQS02844.1 - 8.8 6.3 16.6 1.3 9.0 11.5 2.3 2 0 0 2 2 2 0 HIT zinc finger FYVE PF01363.21 OQS02845.1 - 5.7e-07 29.6 12.0 1.2e-06 28.5 12.0 1.6 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.16 OQS02845.1 - 0.13 12.5 5.1 0.22 11.8 5.1 1.3 1 0 0 1 1 1 0 FYVE-type zinc finger DUF1655 PF07868.11 OQS02845.1 - 0.42 10.7 1.2 1.3 9.1 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1655) zf-B_box PF00643.24 OQS02845.1 - 1.9 8.7 10.5 1.6 8.9 6.3 2.4 2 0 0 2 2 2 0 B-box zinc finger zf-RING_2 PF13639.6 OQS02845.1 - 7.1 7.1 11.7 12 6.3 10.4 2.1 1 1 1 2 2 2 0 Ring finger domain FYVE PF01363.21 OQS02846.1 - 6.8e-10 39.0 29.8 1.8e-05 24.8 11.3 2.5 2 0 0 2 2 2 2 FYVE zinc finger START PF01852.19 OQS02846.1 - 2.6e-08 33.5 3.6 0.00016 21.2 0.0 3.6 4 0 0 4 4 4 2 START domain FYVE_2 PF02318.16 OQS02846.1 - 3.7e-06 27.2 17.1 0.0041 17.3 3.6 2.5 2 0 0 2 2 2 2 FYVE-type zinc finger Cript PF10235.9 OQS02846.1 - 0.0015 19.1 12.5 0.02 15.5 1.5 3.1 2 0 0 2 2 2 2 Microtubule-associated protein CRIPT Siva PF05458.12 OQS02846.1 - 0.029 14.1 21.8 0.09 12.5 4.4 2.7 2 1 0 2 2 2 0 Cd27 binding protein (Siva) IBR PF01485.21 OQS02846.1 - 0.094 13.0 22.6 0.74 10.1 6.6 3.1 2 1 0 2 2 2 0 IBR domain, a half RING-finger domain Strumpellin PF10266.9 OQS02846.1 - 0.16 9.6 0.0 0.36 8.5 0.0 1.4 2 0 0 2 2 2 0 Hereditary spastic paraplegia protein strumpellin zf-C2H2_9 PF16293.5 OQS02846.1 - 0.25 11.2 2.6 0.46 10.4 0.7 2.4 2 0 0 2 2 2 0 C2H2 type zinc-finger (1 copy) zf-HC3 PF16827.5 OQS02846.1 - 1.9 8.8 10.0 4.2 7.6 1.4 3.0 2 0 0 2 2 2 0 zinc-finger DUF2616 PF11077.8 OQS02846.1 - 3.5 7.3 10.4 0.68 9.6 2.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2616) Ras PF00071.22 OQS02848.1 - 1.2e-47 161.5 0.0 1.9e-47 160.9 0.0 1.3 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OQS02848.1 - 2.3e-33 114.9 0.3 4.8e-33 113.9 0.0 1.7 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OQS02848.1 - 3.9e-16 59.0 0.0 6.6e-16 58.3 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 OQS02848.1 - 1.9e-06 27.4 0.0 2.6e-06 26.9 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 OQS02848.1 - 0.00016 21.7 0.0 0.00033 20.7 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 OQS02848.1 - 0.00055 19.5 0.0 0.0012 18.5 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 OQS02848.1 - 0.0033 16.9 0.0 0.006 16.0 0.0 1.4 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit RsgA_GTPase PF03193.16 OQS02848.1 - 0.0037 17.2 0.1 0.11 12.4 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase AAA_16 PF13191.6 OQS02848.1 - 0.021 15.2 0.0 0.077 13.4 0.0 2.0 1 0 0 1 1 1 0 AAA ATPase domain ABC_tran PF00005.27 OQS02848.1 - 0.021 15.3 0.0 0.07 13.6 0.0 1.9 1 0 0 1 1 1 0 ABC transporter G-alpha PF00503.20 OQS02848.1 - 0.029 13.6 0.1 0.24 10.5 0.1 2.1 1 1 1 2 2 2 0 G-protein alpha subunit AAA_5 PF07728.14 OQS02848.1 - 0.034 14.2 0.2 0.92 9.5 0.0 2.5 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) MCM PF00493.23 OQS02848.1 - 0.11 11.6 1.3 0.61 9.1 0.0 2.2 1 1 1 2 2 2 0 MCM P-loop domain Cofilin_ADF PF00241.20 OQS02849.1 - 9.6e-14 51.2 0.0 7.3e-08 32.2 0.0 2.2 2 0 0 2 2 2 2 Cofilin/tropomyosin-type actin-binding protein SNF2_N PF00176.23 OQS02850.1 - 3e-77 259.7 2.1 3e-77 259.7 2.1 1.7 2 0 0 2 2 2 1 SNF2 family N-terminal domain zf-C3HC4_3 PF13920.6 OQS02850.1 - 1.2e-07 31.4 7.6 1.2e-07 31.4 7.6 3.2 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OQS02850.1 - 5.1e-05 23.1 7.2 5.1e-05 23.1 7.2 3.0 3 1 1 4 4 4 1 zinc-RING finger domain zf-RING_2 PF13639.6 OQS02850.1 - 5.3e-05 23.5 10.1 5.3e-05 23.5 10.1 4.0 4 0 0 4 4 4 1 Ring finger domain Helicase_C PF00271.31 OQS02850.1 - 0.00016 22.0 0.0 0.0004 20.7 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4 PF00097.25 OQS02850.1 - 0.00058 19.7 7.9 0.00058 19.7 7.9 3.5 5 0 0 5 5 5 1 Zinc finger, C3HC4 type (RING finger) PHD PF00628.29 OQS02850.1 - 0.00074 19.4 10.1 0.00074 19.4 10.1 3.1 3 0 0 3 3 3 1 PHD-finger Prok-RING_4 PF14447.6 OQS02850.1 - 0.00078 19.3 7.5 0.00078 19.3 7.5 2.7 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 OQS02850.1 - 0.0016 18.4 5.7 0.0016 18.4 5.7 3.9 4 0 0 4 4 4 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 OQS02850.1 - 0.0075 16.1 8.1 0.0075 16.1 8.1 3.6 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) DUF2496 PF10689.9 OQS02851.1 - 0.094 12.5 0.2 0.24 11.2 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2496) eIF3_subunit PF08597.10 OQS02852.1 - 3.5e-32 112.2 15.9 6e-32 111.5 15.9 1.3 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit WD40 PF00400.32 OQS02852.1 - 1.2e-17 63.9 0.9 3e-07 31.0 0.2 5.5 5 0 0 5 5 5 3 WD domain, G-beta repeat TPR_11 PF13414.6 OQS02852.1 - 8.1e-08 31.8 0.0 1.3e-06 28.0 0.0 2.3 2 0 0 2 2 2 1 TPR repeat TPR_1 PF00515.28 OQS02852.1 - 1.6e-06 27.6 1.7 0.00037 20.2 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 OQS02852.1 - 5.9e-06 26.0 3.6 0.0056 16.7 0.0 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 OQS02852.1 - 1.4e-05 25.6 4.7 3e-05 24.6 0.0 2.8 3 0 0 3 3 2 1 Tetratricopeptide repeat ANAPC4_WD40 PF12894.7 OQS02852.1 - 3.1e-05 24.2 0.1 0.089 13.1 0.0 3.7 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain TPR_8 PF13181.6 OQS02852.1 - 0.00019 21.4 2.0 0.00045 20.2 0.0 2.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 OQS02852.1 - 0.00022 21.4 1.9 0.0024 18.1 0.5 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.6 OQS02852.1 - 0.00077 19.9 0.9 0.00077 19.9 0.9 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat ANAPC3 PF12895.7 OQS02852.1 - 0.0018 18.4 0.4 0.0018 18.4 0.4 2.5 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_3 PF07720.12 OQS02852.1 - 0.0041 17.1 0.1 0.19 11.8 0.0 3.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_20 PF14561.6 OQS02852.1 - 0.0067 16.7 0.2 0.024 14.9 0.2 2.0 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_14 PF13428.6 OQS02852.1 - 0.013 16.3 4.2 0.024 15.4 0.0 3.5 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.6 OQS02852.1 - 0.02 15.5 0.4 22 6.0 0.0 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat DPM3 PF08285.11 OQS02852.1 - 0.098 12.9 0.1 0.52 10.5 0.1 2.3 1 0 0 1 1 1 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) 2OG-FeII_Oxy_2 PF13532.6 OQS02853.1 - 1.2e-31 110.5 0.0 4.5e-31 108.6 0.0 2.0 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily UPF0054 PF02130.17 OQS02853.1 - 2.2e-29 101.9 0.0 3.7e-29 101.1 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized protein family UPF0054 Mito_carr PF00153.27 OQS02854.1 - 1.1e-19 70.2 5.3 3e-07 30.3 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF1447 PF07288.11 OQS02855.1 - 0.052 13.6 5.0 0.095 12.8 5.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1447) DUF1366 PF07104.11 OQS02855.1 - 1.7 8.4 7.9 0.21 11.3 3.2 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1366) Myosin_head PF00063.21 OQS02856.1 - 1.5e-201 671.1 0.0 2.5e-201 670.5 0.0 1.3 1 0 0 1 1 1 1 Myosin head (motor domain) PX PF00787.24 OQS02856.1 - 1.4e-10 41.1 0.0 3.6e-10 39.8 0.0 1.7 1 0 0 1 1 1 1 PX domain IQ PF00612.27 OQS02856.1 - 3.2e-08 32.6 22.1 0.00062 19.3 0.6 4.9 4 0 0 4 4 4 3 IQ calmodulin-binding motif AAA_22 PF13401.6 OQS02856.1 - 0.02 15.1 1.5 0.044 14.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.6 OQS02856.1 - 0.026 14.9 0.0 0.82 10.0 0.0 2.6 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 OQS02856.1 - 0.17 12.4 0.9 0.74 10.3 0.0 2.5 2 0 0 2 2 2 0 ABC transporter Collagen PF01391.18 OQS02856.1 - 0.27 11.0 3.5 0.57 10.0 3.5 1.4 1 0 0 1 1 1 0 Collagen triple helix repeat (20 copies) AAA_16 PF13191.6 OQS02856.1 - 0.38 11.1 0.0 0.38 11.1 0.0 4.2 3 1 0 3 3 3 0 AAA ATPase domain NDUFB10 PF10249.9 OQS02857.1 - 0.0013 19.3 0.0 0.0015 19.0 0.0 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase subunit 10 Sec63 PF02889.16 OQS02858.1 - 9.6e-106 352.6 9.0 1.3e-73 247.3 2.6 2.8 3 0 0 3 3 3 2 Sec63 Brl domain DEAD PF00270.29 OQS02858.1 - 9.3e-54 181.8 3.1 3.3e-28 98.7 1.6 3.1 3 0 0 3 3 3 2 DEAD/DEAH box helicase ResIII PF04851.15 OQS02858.1 - 6.1e-28 97.9 0.0 3.5e-15 56.4 0.3 2.7 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Helicase_C PF00271.31 OQS02858.1 - 2.4e-17 63.3 0.0 2.5e-07 31.0 0.0 4.5 3 2 0 3 3 3 2 Helicase conserved C-terminal domain AAA_22 PF13401.6 OQS02858.1 - 3.8e-10 40.2 0.5 0.00064 20.0 0.1 3.1 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.6 OQS02858.1 - 2.5e-06 27.9 6.0 0.012 16.0 0.0 3.3 3 0 0 3 3 2 2 AAA domain AAA_16 PF13191.6 OQS02858.1 - 5.6e-05 23.6 0.1 0.47 10.8 0.0 3.0 2 0 0 2 2 2 2 AAA ATPase domain T2SSE PF00437.20 OQS02858.1 - 0.00037 19.7 0.0 1.2 8.2 0.0 3.1 3 0 0 3 3 3 2 Type II/IV secretion system protein AAA_7 PF12775.7 OQS02858.1 - 0.0011 18.5 0.0 1.3 8.5 0.0 2.5 2 0 0 2 2 2 2 P-loop containing dynein motor region PhoH PF02562.16 OQS02858.1 - 0.0018 17.7 0.1 1.1 8.7 0.0 2.6 2 0 0 2 2 2 2 PhoH-like protein UvrD-helicase PF00580.21 OQS02858.1 - 0.0041 16.7 1.9 0.27 10.7 0.2 3.0 3 0 0 3 3 3 1 UvrD/REP helicase N-terminal domain Helicase_PWI PF18149.1 OQS02858.1 - 0.015 15.4 3.4 0.031 14.4 0.0 2.9 3 0 0 3 3 3 0 N-terminal helicase PWI domain Sigma54_activat PF00158.26 OQS02858.1 - 0.025 14.3 0.0 2.2 7.9 0.0 2.6 2 0 0 2 2 2 0 Sigma-54 interaction domain IstB_IS21 PF01695.17 OQS02858.1 - 0.062 13.0 0.2 2.3 7.9 0.0 3.0 3 0 0 3 3 3 0 IstB-like ATP binding protein RRP7 PF12923.7 OQS02858.1 - 0.077 13.1 0.4 0.19 11.9 0.4 1.6 1 0 0 1 1 1 0 Ribosomal RNA-processing protein 7 (RRP7) C-terminal domain AAA_25 PF13481.6 OQS02858.1 - 0.32 10.5 1.6 5.2 6.6 0.1 3.0 3 0 0 3 3 3 0 AAA domain AAA_11 PF13086.6 OQS02858.1 - 1.1 9.0 9.8 0.061 13.1 0.5 3.2 3 2 2 5 5 5 0 AAA domain IQ PF00612.27 OQS02859.1 - 3.7e-12 44.9 16.1 0.00088 18.9 0.8 5.1 4 0 0 4 4 4 4 IQ calmodulin-binding motif Anoctamin PF04547.12 OQS02860.1 - 1.9e-256 851.0 16.1 4.7e-130 434.4 4.7 2.1 2 0 0 2 2 2 2 Calcium-activated chloride channel Anoct_dimer PF16178.5 OQS02860.1 - 3e-27 95.8 1.1 2.2e-12 47.2 0.2 2.4 2 0 0 2 2 2 2 Dimerisation domain of Ca+-activated chloride-channel, anoctamin RSN1_7TM PF02714.15 OQS02860.1 - 0.0018 17.6 11.5 0.037 13.3 0.7 2.8 2 0 0 2 2 2 2 Calcium-dependent channel, 7TM region, putative phosphate Pam17 PF08566.10 OQS02860.1 - 0.052 13.4 3.1 4.1 7.2 0.1 2.6 2 0 0 2 2 2 0 Mitochondrial import protein Pam17 DUF3377 PF11857.8 OQS02860.1 - 0.29 11.1 1.9 9.7 6.2 0.3 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3377) DUF3040 PF11239.8 OQS02860.1 - 3 8.2 15.6 0.71 10.2 0.1 3.6 4 0 0 4 4 4 0 Protein of unknown function (DUF3040) DUF1077 PF06417.12 OQS02860.1 - 3.5 7.7 8.5 17 5.4 1.1 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1077) PDZ_6 PF17820.1 OQS02861.1 - 1.1e-08 34.7 0.4 4.4e-06 26.4 0.1 2.8 3 0 0 3 3 3 2 PDZ domain DUSP PF06337.12 OQS02861.1 - 3.4e-06 27.6 0.0 7.5e-06 26.5 0.0 1.6 1 0 0 1 1 1 1 DUSP domain PDZ PF00595.24 OQS02861.1 - 0.00011 22.4 0.1 0.39 11.1 0.0 2.4 2 0 0 2 2 2 2 PDZ domain Presenilin PF01080.17 OQS02861.1 - 0.23 10.2 0.3 16 4.2 0.0 2.1 2 0 0 2 2 2 0 Presenilin CDC45 PF02724.14 OQS02862.1 - 2e-172 574.9 0.6 2e-172 574.9 0.6 2.4 2 0 0 2 2 2 1 CDC45-like protein Use1 PF09753.9 OQS02864.1 - 1.2e-06 28.5 1.2 0.00069 19.4 0.0 2.6 2 1 1 3 3 3 2 Membrane fusion protein Use1 CCSMST1 PF15013.6 OQS02864.1 - 0.0024 18.0 1.9 0.023 14.8 0.0 3.1 4 0 0 4 4 3 1 CCSMST1 family Ferric_reduct PF01794.19 OQS02864.1 - 0.0059 16.7 0.2 0.56 10.3 0.0 2.7 3 0 0 3 3 3 1 Ferric reductase like transmembrane component DUF3290 PF11694.8 OQS02864.1 - 0.015 15.3 0.3 0.015 15.3 0.3 3.3 3 1 0 4 4 4 0 Protein of unknown function (DUF3290) Spore_III_AB PF09548.10 OQS02864.1 - 0.025 14.7 5.6 3 7.9 0.3 3.3 3 1 1 4 4 4 0 Stage III sporulation protein AB (spore_III_AB) SNARE PF05739.19 OQS02864.1 - 0.029 14.3 5.5 4.2 7.4 0.1 4.5 4 0 0 4 4 4 0 SNARE domain DUF4064 PF13273.6 OQS02864.1 - 0.054 13.8 1.1 2.4 8.5 0.0 3.2 3 1 1 4 4 4 0 Protein of unknown function (DUF4064) DUF5383 PF17355.2 OQS02864.1 - 0.068 13.6 0.3 4.4 7.7 0.0 3.0 3 0 0 3 3 3 0 Family of unknown function (DUF5383) Glt_symporter PF03616.14 OQS02864.1 - 0.082 11.6 4.7 0.1 11.3 1.5 2.1 1 1 0 2 2 2 0 Sodium/glutamate symporter MAP17 PF15807.5 OQS02864.1 - 0.11 12.7 0.0 0.34 11.1 0.0 1.9 1 0 0 1 1 1 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 BatD PF13584.6 OQS02864.1 - 0.16 10.7 0.2 0.53 9.0 0.1 1.8 2 1 0 2 2 2 0 Oxygen tolerance TRIQK PF15168.6 OQS02864.1 - 0.2 11.6 3.4 11 6.0 0.1 2.8 3 0 0 3 3 3 0 Triple QxxK/R motif-containing protein family DUF1240 PF06836.12 OQS02864.1 - 0.2 12.2 8.4 4.5 7.9 0.1 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1240) DUF948 PF06103.11 OQS02864.1 - 0.25 11.6 7.9 1.5 9.1 0.0 3.4 3 1 0 3 3 3 0 Bacterial protein of unknown function (DUF948) Pox_EPC_I2-L1 PF12575.8 OQS02864.1 - 0.67 10.2 3.8 2.8 8.2 0.2 3.0 3 0 0 3 3 3 0 Poxvirus entry protein complex L1 and I2 Ly49 PF08391.10 OQS02864.1 - 0.74 10.2 11.9 0.74 10.2 0.2 3.4 1 1 3 4 4 4 0 Ly49-like protein, N-terminal region Phage_lysis PF03245.13 OQS02864.1 - 2.4 8.3 13.5 3.6 7.7 0.3 3.7 3 1 0 3 3 3 0 Bacteriophage Rz lysis protein OppC_N PF12911.7 OQS02864.1 - 2.8 8.0 8.5 2.3 8.3 0.0 3.6 4 0 0 4 4 4 0 N-terminal TM domain of oligopeptide transport permease C EphA2_TM PF14575.6 OQS02864.1 - 5.1 8.0 5.5 1.6 9.7 0.1 2.9 2 1 2 4 4 3 0 Ephrin type-A receptor 2 transmembrane domain Synaptobrevin PF00957.21 OQS02864.1 - 10 6.0 13.3 6.1 6.7 2.2 4.5 3 1 2 5 5 5 0 Synaptobrevin Sugar_tr PF00083.24 OQS02865.1 - 1.4e-51 175.7 19.4 1.8e-51 175.4 19.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OQS02865.1 - 1.2e-41 142.8 42.0 1e-36 126.6 21.5 2.5 1 1 2 3 3 3 2 Major Facilitator Superfamily MFS_4 PF06779.14 OQS02865.1 - 1.3e-05 24.7 5.7 1.3e-05 24.7 5.7 2.1 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB TRI12 PF06609.13 OQS02865.1 - 1.7e-05 23.5 2.3 3.6e-05 22.4 2.3 1.5 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Isochorismatase PF00857.20 OQS02866.1 - 5.5e-17 62.5 0.0 1.7e-16 60.9 0.0 1.7 1 1 0 1 1 1 1 Isochorismatase family CX9C PF16860.5 OQS02867.1 - 0.035 14.1 0.2 0.05 13.6 0.2 1.2 1 0 0 1 1 1 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, Sugar_tr PF00083.24 OQS02868.1 - 1.6e-48 165.7 21.1 2.1e-48 165.4 21.1 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OQS02868.1 - 2.5e-46 158.3 35.1 7.2e-34 117.3 16.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 OQS02868.1 - 2.1e-06 27.3 7.1 2.1e-06 27.3 7.1 2.3 2 0 0 2 2 2 2 Uncharacterised MFS-type transporter YbfB TRI12 PF06609.13 OQS02868.1 - 4.2e-06 25.5 2.7 5.7e-06 25.0 2.7 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) p450 PF00067.22 OQS02869.1 - 2.9e-92 309.9 0.6 3.3e-92 309.7 0.6 1.0 1 0 0 1 1 1 1 Cytochrome P450 Sulfotransfer_3 PF13469.6 OQS02869.1 - 0.063 13.6 0.2 0.23 11.8 0.2 2.1 1 1 0 1 1 1 0 Sulfotransferase family Trp_repressor PF01371.19 OQS02869.1 - 0.15 12.2 0.1 0.35 11.0 0.1 1.6 1 0 0 1 1 1 0 Trp repressor protein PLDc_2 PF13091.6 OQS02870.1 - 1.2e-18 67.3 0.0 1.4e-08 34.7 0.0 2.4 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.22 OQS02870.1 - 0.00037 20.5 1.3 0.27 11.5 0.0 2.5 2 0 0 2 2 2 2 Phospholipase D Active site motif VWA_3 PF13768.6 OQS02870.1 - 0.0069 16.3 0.0 1.1 9.2 0.0 2.4 2 0 0 2 2 2 2 von Willebrand factor type A domain Sugar_tr PF00083.24 OQS02871.1 - 3.2e-51 174.6 25.7 4e-51 174.3 25.7 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OQS02871.1 - 1.4e-42 145.9 38.3 6.4e-32 110.8 21.8 2.4 1 1 2 3 3 3 2 Major Facilitator Superfamily MFS_4 PF06779.14 OQS02871.1 - 7.9e-08 32.0 21.4 1.7e-07 30.9 5.7 2.2 2 0 0 2 2 2 2 Uncharacterised MFS-type transporter YbfB TRI12 PF06609.13 OQS02871.1 - 1.5e-05 23.6 3.2 2.7e-05 22.8 3.2 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_5 PF05631.14 OQS02871.1 - 5e-05 22.4 0.7 5e-05 22.4 0.7 2.5 3 0 0 3 3 3 1 Sugar-tranasporters, 12 TM SDF PF00375.18 OQS02872.1 - 1.4e-64 218.5 31.9 1e-63 215.7 31.9 1.9 1 1 0 1 1 1 1 Sodium:dicarboxylate symporter family DUF4501 PF14946.6 OQS02872.1 - 0.0091 16.1 0.3 0.035 14.2 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4501) Oxidored_FMN PF00724.20 OQS02873.1 - 1.6e-47 162.4 0.0 1.8e-47 162.3 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family HECT PF00632.25 OQS02875.1 - 1.8e-12 47.4 0.0 2e-12 47.2 0.0 1.0 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) RCC1_2 PF13540.6 OQS02876.1 - 0.0057 16.4 0.1 0.0089 15.8 0.1 1.3 1 0 0 1 1 1 1 Regulator of chromosome condensation (RCC1) repeat RCC1 PF00415.18 OQS02876.1 - 0.026 15.1 0.0 2.8 8.6 0.0 2.2 2 0 0 2 2 2 0 Regulator of chromosome condensation (RCC1) repeat Hira PF07569.11 OQS02876.1 - 0.057 13.1 0.0 0.064 13.0 0.0 1.1 1 0 0 1 1 1 0 TUP1-like enhancer of split Oxidored_FMN PF00724.20 OQS02877.1 - 3.1e-82 276.6 0.0 3.6e-82 276.4 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Cation_efflux PF01545.21 OQS02878.1 - 8.7e-56 188.8 25.0 4.1e-28 98.5 5.2 2.5 2 0 0 2 2 2 2 Cation efflux family GCP_C_terminal PF04130.13 OQS02878.1 - 4.2e-29 102.0 11.8 6.9e-29 101.3 11.8 1.4 1 0 0 1 1 1 1 Gamma tubulin complex component C-terminal DUF2807 PF10988.8 OQS02878.1 - 1.6e-11 44.4 9.5 2e-08 34.2 5.8 2.9 1 1 1 2 2 2 2 Putative auto-transporter adhesin, head GIN domain ZT_dimer PF16916.5 OQS02878.1 - 9.5e-10 38.5 0.2 2.9e-09 36.9 0.2 1.9 1 0 0 1 1 1 1 Dimerisation domain of Zinc Transporter GCP_N_terminal PF17681.1 OQS02878.1 - 0.00084 19.0 0.2 0.00084 19.0 0.2 2.4 2 0 0 2 2 2 1 Gamma tubulin complex component N-terminal ODV-E18 PF10717.9 OQS02878.1 - 1 9.3 3.5 3.9 7.4 0.3 2.8 2 0 0 2 2 2 0 Occlusion-derived virus envelope protein ODV-E18 ABC_tran PF00005.27 OQS02879.1 - 1.9e-27 96.4 0.0 3.1e-27 95.7 0.0 1.3 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 OQS02879.1 - 2.4e-07 30.4 1.1 0.00094 18.7 0.1 2.2 1 1 1 2 2 2 2 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 OQS02879.1 - 0.00087 19.4 0.0 0.0015 18.6 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_21 PF13304.6 OQS02879.1 - 0.0017 18.2 0.0 0.042 13.7 0.0 2.1 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system Sigma54_activat PF00158.26 OQS02879.1 - 0.0049 16.6 0.0 0.0086 15.8 0.0 1.3 1 0 0 1 1 1 1 Sigma-54 interaction domain DUF87 PF01935.17 OQS02879.1 - 0.0064 16.6 0.1 0.013 15.6 0.1 1.5 1 0 0 1 1 1 1 Helicase HerA, central domain MeaB PF03308.16 OQS02879.1 - 0.011 14.8 0.0 0.017 14.1 0.0 1.2 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB T2SSE PF00437.20 OQS02879.1 - 0.016 14.3 0.1 0.05 12.7 0.0 1.8 2 1 0 2 2 2 0 Type II/IV secretion system protein AAA_29 PF13555.6 OQS02879.1 - 0.037 13.8 0.1 0.087 12.6 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain RNA_helicase PF00910.22 OQS02879.1 - 0.041 14.3 0.0 1.8 9.0 0.0 2.5 2 0 0 2 2 2 0 RNA helicase AAA_22 PF13401.6 OQS02879.1 - 0.053 13.8 0.6 0.49 10.7 0.6 2.2 1 1 0 1 1 1 0 AAA domain AAA_24 PF13479.6 OQS02879.1 - 0.12 12.0 0.1 0.18 11.5 0.1 1.4 1 1 0 1 1 1 0 AAA domain AAA_23 PF13476.6 OQS02879.1 - 0.13 12.7 0.1 0.23 11.9 0.1 1.3 1 0 0 1 1 1 0 AAA domain AAA_15 PF13175.6 OQS02879.1 - 0.21 11.3 0.0 0.25 11.0 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain C2 PF00168.30 OQS02880.1 - 2e-05 24.8 0.2 3e-05 24.3 0.2 1.3 1 0 0 1 1 1 1 C2 domain Pkinase_Tyr PF07714.17 OQS02880.1 - 0.00099 18.5 0.6 0.006 15.9 0.1 2.3 2 1 0 2 2 2 1 Protein tyrosine kinase WG_beta_rep PF14903.6 OQS02880.1 - 0.088 13.1 0.1 11 6.5 0.0 2.8 2 0 0 2 2 2 0 WG containing repeat DUF4211 PF13926.6 OQS02881.1 - 4.4e-18 65.7 0.1 4.4e-18 65.7 0.1 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF4211) zf-C3HC4_3 PF13920.6 OQS02881.1 - 2.1e-06 27.5 12.0 2.1e-06 27.5 12.0 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Utp11 PF03998.13 OQS02881.1 - 0.4 10.6 5.3 0.24 11.3 3.3 1.6 2 0 0 2 2 2 0 Utp11 protein Podoplanin PF05808.11 OQS02882.1 - 5.4e-05 23.4 9.4 5.4e-05 23.4 9.4 2.0 2 1 0 2 2 2 1 Podoplanin Yae1_N PF09811.9 OQS02882.1 - 0.085 12.6 0.0 0.12 12.1 0.0 1.2 1 0 0 1 1 1 0 Essential protein Yae1, N terminal DUF4064 PF13273.6 OQS02882.1 - 0.1 12.9 0.0 0.21 11.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4064) Mid2 PF04478.12 OQS02882.1 - 0.11 12.3 0.3 0.11 12.3 0.3 2.0 1 1 1 2 2 2 0 Mid2 like cell wall stress sensor MtrF PF09472.10 OQS02882.1 - 0.25 10.8 1.0 0.5 9.8 1.0 1.5 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, F subunit (MtrF) SKG6 PF08693.10 OQS02882.1 - 0.5 9.8 4.4 1.3 8.5 4.4 1.7 1 1 0 1 1 1 0 Transmembrane alpha-helix domain PAM2 PF07145.15 OQS02882.1 - 4.6 7.2 6.7 63 3.6 1.5 3.9 3 1 1 4 4 4 0 Ataxin-2 C-terminal region Cupredoxin_1 PF13473.6 OQS02883.1 - 2.1e-07 31.0 1.2 0.0014 18.7 0.0 3.1 2 1 1 3 3 3 2 Cupredoxin-like domain Copper-bind PF00127.20 OQS02883.1 - 0.00022 21.6 0.0 0.16 12.5 0.0 2.9 2 0 0 2 2 2 2 Copper binding proteins, plastocyanin/azurin family Calponin PF00402.18 OQS02883.1 - 0.096 12.3 0.1 0.18 11.5 0.1 1.5 1 0 0 1 1 1 0 Calponin family repeat Pkinase_Tyr PF07714.17 OQS02884.1 - 9e-18 64.5 0.0 6.2e-17 61.7 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OQS02884.1 - 3e-16 59.6 0.0 6.7e-16 58.4 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQS02885.1 - 1.7e-30 106.2 0.0 3.5e-30 105.1 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OQS02885.1 - 1.5e-26 93.3 0.0 2.7e-26 92.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain C2 PF00168.30 OQS02885.1 - 8.5e-17 61.3 0.0 9.2e-16 58.0 0.0 2.2 2 0 0 2 2 2 1 C2 domain APG6_N PF17675.1 OQS02885.1 - 0.0039 17.7 9.7 0.0065 17.0 9.7 1.3 1 0 0 1 1 1 1 Apg6 coiled-coil region ATPase PF06745.13 OQS02885.1 - 0.011 15.0 1.8 0.019 14.3 1.8 1.2 1 0 0 1 1 1 0 KaiC DUF4094 PF13334.6 OQS02885.1 - 0.015 15.7 1.0 0.032 14.6 1.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4094) Kdo PF06293.14 OQS02885.1 - 0.057 12.8 0.0 0.12 11.7 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Ax_dynein_light PF10211.9 OQS02885.1 - 0.14 12.1 8.6 0.23 11.4 8.6 1.3 1 0 0 1 1 1 0 Axonemal dynein light chain Bap31_Bap29_C PF18035.1 OQS02885.1 - 0.61 10.1 3.6 1.4 9.0 3.6 1.7 1 0 0 1 1 1 0 Bap31/Bap29 cytoplasmic coiled-coil domain IFT20 PF14931.6 OQS02885.1 - 0.94 9.7 7.4 1.2 9.4 6.4 1.7 1 1 0 1 1 1 0 Intraflagellar transport complex B, subunit 20 DUF2120 PF09893.9 OQS02885.1 - 2.7 8.1 5.4 5.6 7.1 0.2 2.3 1 1 1 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2120) DUF1713 PF08213.11 OQS02886.1 - 4.4e-08 32.9 16.8 6.3e-08 32.4 16.8 1.3 1 0 0 1 1 1 1 Mitochondrial domain of unknown function (DUF1713) Syntaxin-6_N PF09177.11 OQS02887.1 - 0.062 13.9 0.7 0.073 13.6 0.7 1.2 1 0 0 1 1 1 0 Syntaxin 6, N-terminal Pkinase PF00069.25 OQS02888.1 - 8.5e-31 107.3 0.0 1.8e-30 106.2 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQS02888.1 - 3.3e-30 105.3 0.0 7.5e-30 104.1 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase C2 PF00168.30 OQS02888.1 - 3.4e-14 53.0 0.1 1e-13 51.4 0.0 1.9 2 0 0 2 2 2 1 C2 domain Kdo PF06293.14 OQS02888.1 - 0.00039 19.8 0.1 0.0016 17.8 0.1 2.0 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Bap31_Bap29_C PF18035.1 OQS02888.1 - 0.12 12.4 1.1 0.28 11.2 1.1 1.6 1 0 0 1 1 1 0 Bap31/Bap29 cytoplasmic coiled-coil domain APH PF01636.23 OQS02888.1 - 0.39 10.6 4.6 5.1 7.0 0.2 3.5 3 1 1 4 4 4 0 Phosphotransferase enzyme family Ank_2 PF12796.7 OQS02889.1 - 8.6e-44 148.0 30.2 3.6e-07 30.7 0.2 5.5 1 1 8 9 9 9 9 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQS02889.1 - 9.4e-27 93.0 13.8 1.1e-05 25.9 0.4 8.2 1 1 6 8 8 8 8 Ankyrin repeats (many copies) Ank_5 PF13857.6 OQS02889.1 - 1.7e-25 88.7 15.8 0.004 17.4 0.1 10.7 2 1 9 11 11 11 8 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQS02889.1 - 3e-19 67.1 6.6 1.1 10.0 0.0 10.4 10 1 1 11 11 11 5 Ankyrin repeat Ank PF00023.30 OQS02889.1 - 7.7e-05 23.0 5.1 34 5.1 0.1 7.4 5 3 1 6 6 6 0 Ankyrin repeat DUF5049 PF16468.5 OQS02889.1 - 0.00038 20.3 4.5 25 4.8 0.0 6.7 4 3 3 7 7 7 1 Domain of unknown function (DUF5049) Pkinase_Tyr PF07714.17 OQS02890.1 - 0.00031 20.1 0.0 0.031 13.6 0.0 2.2 1 1 1 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 OQS02890.1 - 0.00036 20.0 0.1 0.0025 17.2 0.0 2.0 2 0 0 2 2 2 1 Protein kinase domain C2 PF00168.30 OQS02890.1 - 0.0012 19.1 0.0 0.0029 17.9 0.0 1.7 1 1 1 2 2 2 1 C2 domain adh_short_C2 PF13561.6 OQS02891.1 - 4.5e-60 203.1 0.1 5.1e-60 202.9 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OQS02891.1 - 1.1e-47 162.0 0.7 1.4e-47 161.7 0.7 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OQS02891.1 - 1.9e-11 44.2 0.5 5e-11 42.8 0.6 1.5 1 1 1 2 2 2 1 KR domain Epimerase PF01370.21 OQS02891.1 - 0.0093 15.4 0.2 0.026 14.0 0.2 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF1776 PF08643.10 OQS02891.1 - 0.1 11.9 0.1 0.13 11.6 0.1 1.3 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) THF_DHG_CYH_C PF02882.19 OQS02891.1 - 0.1 11.9 0.3 0.37 10.1 0.1 1.9 1 1 1 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Pkinase PF00069.25 OQS02892.1 - 1.2e-27 96.9 0.1 2e-27 96.2 0.1 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQS02892.1 - 1.9e-21 76.5 0.0 3e-21 75.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase C2 PF00168.30 OQS02892.1 - 3.7e-09 36.8 0.1 1e-08 35.4 0.1 1.7 1 0 0 1 1 1 1 C2 domain Kinase-like PF14531.6 OQS02892.1 - 1e-05 25.0 0.0 1.9e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 OQS02892.1 - 0.0045 16.4 0.1 0.015 14.7 0.0 1.8 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family zf-CpG_bind_C PF12269.8 OQS02892.1 - 0.035 13.9 2.0 0.04 13.7 0.9 1.6 1 1 0 1 1 1 0 CpG binding protein zinc finger C terminal domain Cu-oxidase PF00394.22 OQS02894.1 - 1.4e-35 122.8 0.1 1e-34 120.0 0.0 2.3 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_3 PF07732.15 OQS02894.1 - 1.3e-33 115.5 7.3 8.4e-32 109.7 1.7 3.7 3 0 0 3 3 3 1 Multicopper oxidase YTH PF04146.15 OQS02894.1 - 3.5e-27 95.4 0.5 1.2e-26 93.7 0.5 1.9 1 1 0 1 1 1 1 YT521-B-like domain Phosphodiest PF01663.22 OQS02894.1 - 8.8e-24 84.7 0.1 2.1e-23 83.5 0.1 1.6 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Cu-oxidase_2 PF07731.14 OQS02894.1 - 2.2e-15 56.6 9.0 2.9e-14 53.0 0.1 3.4 3 1 0 3 3 3 2 Multicopper oxidase Sulfatase PF00884.23 OQS02894.1 - 9.8e-05 21.9 0.0 0.00018 21.0 0.0 1.4 1 0 0 1 1 1 1 Sulfatase Marek_A PF02124.15 OQS02894.1 - 0.078 12.8 0.1 0.28 11.0 0.0 1.9 2 0 0 2 2 2 0 Marek's disease glycoprotein A DUF229 PF02995.17 OQS02894.1 - 0.08 11.5 0.0 0.12 11.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF229) C2 PF00168.30 OQS02895.1 - 5.6e-18 65.1 0.0 1.3e-17 64.0 0.0 1.6 1 0 0 1 1 1 1 C2 domain Filament PF00038.21 OQS02895.1 - 0.0019 17.8 38.1 0.0019 17.8 38.1 9.9 2 2 5 8 8 8 5 Intermediate filament protein FAM76 PF16046.5 OQS02895.1 - 0.0021 17.5 5.8 0.0021 17.5 5.8 8.8 2 2 7 10 10 10 3 FAM76 protein CENP-F_leu_zip PF10473.9 OQS02895.1 - 0.0022 18.0 12.5 0.0022 18.0 12.5 14.0 2 2 10 13 13 13 5 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Pox_A_type_inc PF04508.12 OQS02895.1 - 0.91 9.5 6.8 30 4.7 0.1 5.4 6 0 0 6 6 6 0 Viral A-type inclusion protein repeat Surfac_D-trimer PF09006.11 OQS02895.1 - 1.1 9.2 7.6 44 4.1 0.0 6.0 5 0 0 5 5 5 0 Lung surfactant protein D coiled-coil trimerisation Sec16_C PF12931.7 OQS02896.1 - 9.7e-49 166.6 0.0 1.4e-48 166.1 0.0 1.2 1 0 0 1 1 1 1 Sec23-binding domain of Sec16 Sec16 PF12932.7 OQS02896.1 - 6.8e-07 29.9 0.1 4.4e-06 27.3 0.1 2.3 1 1 0 1 1 1 1 Vesicle coat trafficking protein Sec16 mid-region CDC27 PF09507.10 OQS02896.1 - 0.19 11.1 6.4 10 5.4 6.3 2.4 2 0 0 2 2 2 0 DNA polymerase subunit Cdc27 DUF4164 PF13747.6 OQS02896.1 - 0.21 11.9 0.5 0.41 11.0 0.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4164) Proteasome PF00227.26 OQS02897.1 - 3.5e-50 170.1 0.1 4.7e-50 169.7 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 OQS02897.1 - 2.3e-15 55.9 0.1 4e-15 55.2 0.1 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature DUF5018 PF16410.5 OQS02897.1 - 0.012 14.3 0.0 0.021 13.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5018) NAGidase PF07555.13 OQS02897.1 - 0.032 13.6 0.0 0.042 13.2 0.0 1.1 1 0 0 1 1 1 0 beta-N-acetylglucosaminidase YukC PF10140.9 OQS02898.1 - 0.018 13.9 0.1 0.018 13.9 0.1 1.0 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukC Rtt106 PF08512.12 OQS02898.1 - 0.067 13.6 0.1 0.12 12.8 0.1 1.5 1 1 1 2 2 2 0 Histone chaperone Rttp106-like Metallophos PF00149.28 OQS02899.1 - 1.7e-32 113.6 0.0 2.1e-31 110.0 0.0 2.2 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase EF-hand_7 PF13499.6 OQS02899.1 - 2.2e-05 24.8 0.4 2.2e-05 24.8 0.4 2.6 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_1 PF00036.32 OQS02899.1 - 9.7e-05 21.7 1.6 0.34 10.6 0.0 3.0 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 OQS02899.1 - 0.00038 20.2 1.2 1.3 9.1 0.2 3.1 3 0 0 3 3 3 2 EF-hand domain SPARC_Ca_bdg PF10591.9 OQS02899.1 - 0.029 14.7 0.3 0.063 13.6 0.3 1.6 1 0 0 1 1 1 0 Secreted protein acidic and rich in cysteine Ca binding region Dockerin_1 PF00404.18 OQS02899.1 - 0.089 13.0 0.0 0.17 12.1 0.0 1.4 1 0 0 1 1 1 0 Dockerin type I domain C2 PF00168.30 OQS02900.1 - 8e-23 80.7 0.1 5.1e-20 71.7 0.0 2.5 2 0 0 2 2 2 2 C2 domain Pex24p PF06398.11 OQS02900.1 - 4e-05 22.8 1.6 4e-05 22.8 1.6 1.9 2 1 1 3 3 3 1 Integral peroxisomal membrane peroxin DUF3450 PF11932.8 OQS02900.1 - 0.13 11.6 8.3 0.096 12.0 6.5 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3450) DUF4407 PF14362.6 OQS02900.1 - 2.8 7.2 8.2 4.2 6.6 8.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF4790 PF16037.5 OQS02900.1 - 4.7 7.7 6.8 11 6.6 2.3 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4790) Glutaredoxin PF00462.24 OQS02901.1 - 2.3e-21 75.8 0.0 3.6e-21 75.1 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin SH3BGR PF04908.15 OQS02901.1 - 0.0027 17.8 0.0 0.0067 16.6 0.0 1.6 1 1 0 1 1 1 1 SH3-binding, glutamic acid-rich protein DUF656 PF04920.12 OQS02901.1 - 0.018 15.0 0.0 0.027 14.4 0.0 1.4 1 1 0 1 1 1 0 Family of unknown function (DUF656) PAS PF00989.25 OQS02902.1 - 1.9e-130 427.3 3.9 1.7e-19 69.9 0.0 8.1 8 0 0 8 8 8 7 PAS fold PAS_4 PF08448.10 OQS02902.1 - 2.8e-77 256.1 0.0 3e-11 43.5 0.0 7.3 7 0 0 7 7 7 7 PAS fold PAS_9 PF13426.7 OQS02902.1 - 6.7e-65 215.9 15.0 9.5e-11 41.9 0.0 7.4 7 0 0 7 7 7 7 PAS domain PAS_3 PF08447.12 OQS02902.1 - 4.1e-32 110.3 0.0 4.2e-05 23.8 0.0 6.5 6 0 0 6 6 6 6 PAS fold HATPase_c PF02518.26 OQS02902.1 - 8e-27 94.0 0.1 2.1e-26 92.6 0.1 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS_8 PF13188.7 OQS02902.1 - 4e-26 90.5 0.4 8.3e-05 22.5 0.0 7.5 7 0 0 7 7 7 6 PAS domain Response_reg PF00072.24 OQS02902.1 - 5e-21 75.0 0.0 1.2e-20 73.8 0.0 1.7 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 OQS02902.1 - 1.6e-16 60.1 0.0 4.3e-16 58.7 0.0 1.8 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_10 PF13596.6 OQS02902.1 - 2.1e-09 37.9 5.2 0.026 15.1 0.0 6.1 6 0 0 6 6 6 2 PAS domain Hpt PF01627.23 OQS02902.1 - 1e-07 32.1 0.0 2.6e-07 30.8 0.0 1.7 1 0 0 1 1 1 1 Hpt domain PAS_7 PF12860.7 OQS02902.1 - 2.5e-06 27.6 10.3 22 5.3 0.0 9.0 8 4 0 8 8 8 0 PAS fold DUF3189 PF11385.8 OQS02902.1 - 0.035 14.0 0.3 25 4.7 0.0 4.4 5 0 0 5 5 5 0 Protein of unknown function (DUF3189) Ribosomal_S8e PF01201.22 OQS02903.1 - 9.3e-57 191.0 1.6 1.1e-56 190.8 1.6 1.1 1 0 0 1 1 1 1 Ribosomal protein S8e DUF2226 PF09987.9 OQS02903.1 - 0.061 12.7 0.0 0.073 12.4 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2226) C2 PF00168.30 OQS02904.1 - 0.042 14.1 0.0 0.06 13.6 0.0 1.3 1 0 0 1 1 1 0 C2 domain DUF4958 PF16319.5 OQS02904.1 - 0.19 9.7 0.0 0.23 9.4 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4958) Gly-zipper_OmpA PF13436.6 OQS02905.1 - 0.014 15.2 6.2 0.023 14.5 6.2 1.3 1 0 0 1 1 1 0 Glycine-zipper domain Gly-zipper_Omp PF13488.6 OQS02905.1 - 0.014 15.4 7.3 0.023 14.7 7.3 1.3 1 0 0 1 1 1 0 Glycine zipper DUF1269 PF06897.12 OQS02905.1 - 0.075 13.3 0.1 0.17 12.2 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1269) Gly-zipper_YMGG PF13441.6 OQS02905.1 - 0.81 9.5 7.7 1.6 8.5 7.7 1.5 1 1 0 1 1 1 0 YMGG-like Gly-zipper Rick_17kDa_Anti PF05433.15 OQS02905.1 - 9 6.3 10.8 28 4.7 10.9 1.7 1 1 0 1 1 1 0 Glycine zipper 2TM domain EF-hand_1 PF00036.32 OQS02906.1 - 1.2e-08 33.9 1.2 0.0014 18.0 0.0 3.2 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.6 OQS02906.1 - 4.9e-08 32.3 1.4 4.9e-05 22.9 0.1 2.8 3 0 0 3 3 3 2 EF-hand domain EF-hand_7 PF13499.6 OQS02906.1 - 5.3e-08 33.2 0.7 0.00024 21.5 0.2 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 OQS02906.1 - 9.6e-07 28.6 1.6 5.7e-05 22.9 0.0 3.3 3 1 1 4 4 4 2 EF-hand domain pair EF-hand_9 PF14658.6 OQS02906.1 - 0.0002 21.6 0.1 0.26 11.6 0.1 2.6 1 1 1 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 OQS02906.1 - 0.0016 17.8 0.4 2.8 7.6 0.0 3.0 3 0 0 3 3 3 2 EF hand EF-hand_4 PF12763.7 OQS02906.1 - 0.0027 17.7 0.3 0.28 11.1 0.1 2.4 1 1 1 2 2 2 1 Cytoskeletal-regulatory complex EF hand UCH PF00443.29 OQS02907.1 - 3e-42 144.9 3.0 5.8e-42 144.0 3.0 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 OQS02907.1 - 6.7e-16 58.8 12.2 8.7e-16 58.4 5.7 3.0 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.23 OQS02907.1 - 1.1e-12 47.5 0.0 3.5e-12 45.9 0.0 1.8 1 0 0 1 1 1 1 Ubiquitin family zf-RanBP PF00641.18 OQS02907.1 - 1.5e-06 27.4 1.2 1.5e-06 27.4 1.2 3.4 5 0 0 5 5 5 1 Zn-finger in Ran binding protein and others DUSP PF06337.12 OQS02907.1 - 1.7e-06 28.5 6.2 0.0016 19.0 0.2 3.9 4 0 0 4 4 4 2 DUSP domain Rad60-SLD PF11976.8 OQS02907.1 - 2.8e-05 23.9 0.0 7.4e-05 22.5 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like zf-PHD-like PF15446.6 OQS02907.1 - 0.007 16.0 0.0 0.007 16.0 0.0 2.9 3 0 0 3 3 3 1 PHD/FYVE-zinc-finger like domain DUF2318 PF10080.9 OQS02907.1 - 0.59 10.3 5.5 7.6 6.7 0.1 4.1 5 0 0 5 5 5 0 Predicted membrane protein (DUF2318) zf-3CxxC PF13695.6 OQS02907.1 - 1.5 9.4 10.2 3.1 8.3 0.4 3.9 4 0 0 4 4 4 0 Zinc-binding domain TH1 PF04858.13 OQS02908.1 - 6.2e-80 269.5 0.4 1.1e-79 268.7 0.4 1.3 1 0 0 1 1 1 1 TH1 protein Pyr_redox_2 PF07992.14 OQS02908.1 - 4.6e-51 173.8 1.0 9e-51 172.8 0.5 1.8 2 0 0 2 2 1 1 Pyridine nucleotide-disulphide oxidoreductase RRM_1 PF00076.22 OQS02908.1 - 2.2e-26 91.5 0.6 2.5e-15 56.0 0.8 2.7 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Pyr_redox_dim PF02852.22 OQS02908.1 - 1.8e-25 89.4 0.6 5.1e-25 87.9 0.0 2.1 2 0 0 2 2 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain PX PF00787.24 OQS02908.1 - 6.1e-19 68.1 0.0 8.7e-18 64.4 0.0 2.7 2 0 0 2 2 2 1 PX domain TPR_19 PF14559.6 OQS02908.1 - 8.3e-15 55.1 0.0 0.003 18.0 0.2 5.6 5 1 0 5 5 4 3 Tetratricopeptide repeat Pyr_redox PF00070.27 OQS02908.1 - 1e-14 54.8 2.2 1.1e-10 42.0 0.5 3.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase ANAPC3 PF12895.7 OQS02908.1 - 6.7e-13 48.7 17.6 1.6e-06 28.2 0.4 5.4 4 0 0 4 4 4 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.17 OQS02908.1 - 2.3e-09 36.7 19.2 0.0083 16.2 0.4 8.3 8 0 0 8 8 7 1 Tetratricopeptide repeat Pyr_redox_3 PF13738.6 OQS02908.1 - 1.7e-08 34.1 0.9 0.00021 20.6 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 OQS02908.1 - 6.6e-07 29.0 1.3 1.1e-06 28.3 0.0 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 OQS02908.1 - 7.9e-07 28.6 0.3 0.00048 19.5 0.1 2.6 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain TPR_9 PF13371.6 OQS02908.1 - 2.1e-06 27.8 0.4 0.0043 17.2 0.3 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 OQS02908.1 - 2.9e-06 27.8 0.0 0.0079 16.8 0.0 4.3 4 0 0 4 4 3 1 Tetratricopeptide repeat NAD_binding_8 PF13450.6 OQS02908.1 - 4.5e-06 26.8 1.7 0.00099 19.3 0.1 3.4 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain RRM_7 PF16367.5 OQS02908.1 - 5.8e-06 26.3 0.4 2e-05 24.6 0.4 1.9 1 0 0 1 1 1 1 RNA recognition motif WW PF00397.26 OQS02908.1 - 1.6e-05 24.9 0.2 4.6e-05 23.4 0.2 1.8 1 0 0 1 1 1 1 WW domain FAD_binding_2 PF00890.24 OQS02908.1 - 1.8e-05 24.1 0.4 1.8e-05 24.1 0.4 2.5 3 0 0 3 3 3 1 FAD binding domain HI0933_like PF03486.14 OQS02908.1 - 2.6e-05 23.1 6.6 0.00012 20.9 0.2 3.0 2 1 1 3 3 3 1 HI0933-like protein TPR_6 PF13174.6 OQS02908.1 - 7.6e-05 23.1 11.1 0.0066 17.0 0.2 5.3 5 0 0 5 5 3 2 Tetratricopeptide repeat Thi4 PF01946.17 OQS02908.1 - 0.00018 20.8 0.2 0.02 14.1 0.0 2.5 2 0 0 2 2 2 1 Thi4 family DAO PF01266.24 OQS02908.1 - 0.00059 19.5 0.5 0.12 12.0 0.0 2.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase RPN7 PF10602.9 OQS02908.1 - 0.001 18.8 1.1 3.1 7.5 0.0 4.2 3 1 0 3 3 3 1 26S proteasome subunit RPN7 TPR_14 PF13428.6 OQS02908.1 - 0.0013 19.4 0.7 18 6.5 0.1 5.8 4 1 1 5 5 4 0 Tetratricopeptide repeat GIDA PF01134.22 OQS02908.1 - 0.0024 17.0 1.5 0.01 14.9 0.1 2.6 2 0 0 2 2 2 1 Glucose inhibited division protein A TPR_12 PF13424.6 OQS02908.1 - 0.0034 17.6 7.3 0.18 12.1 0.2 4.7 4 1 0 5 5 4 1 Tetratricopeptide repeat TPR_7 PF13176.6 OQS02908.1 - 0.0034 17.3 1.5 1.6 8.9 0.1 3.5 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_10 PF13374.6 OQS02908.1 - 0.0067 16.3 2.2 73 3.4 0.1 5.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.28 OQS02908.1 - 0.0088 15.8 0.3 0.0088 15.8 0.3 4.8 6 0 0 6 6 4 1 Tetratricopeptide repeat 3HCDH_N PF02737.18 OQS02908.1 - 0.02 14.8 0.1 0.02 14.8 0.1 3.6 3 0 0 3 3 3 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain TrkA_N PF02254.18 OQS02908.1 - 0.022 15.0 0.4 1.2 9.4 0.1 2.9 2 0 0 2 2 2 0 TrkA-N domain K_oxygenase PF13434.6 OQS02908.1 - 0.037 13.2 0.0 0.59 9.2 0.0 2.5 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) UDPG_MGDP_dh_N PF03721.14 OQS02908.1 - 0.038 13.6 0.3 5.1 6.6 0.1 3.2 3 0 0 3 3 3 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain PPR PF01535.20 OQS02908.1 - 0.06 13.6 0.2 12 6.4 0.0 4.2 5 0 0 5 5 3 0 PPR repeat DUF3699 PF12480.8 OQS02908.1 - 0.086 13.0 0.0 0.26 11.5 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3699) PGA_cap PF09587.10 OQS02908.1 - 0.28 10.6 0.0 0.28 10.6 0.0 2.0 2 0 0 2 2 1 0 Bacterial capsule synthesis protein PGA_cap TPR_8 PF13181.6 OQS02908.1 - 0.53 10.6 6.7 1.9 8.9 0.1 4.8 5 0 0 5 5 3 0 Tetratricopeptide repeat Lycopene_cycl PF05834.12 OQS02908.1 - 0.55 9.2 4.1 1.1 8.2 0.1 2.8 3 0 0 3 3 3 0 Lycopene cyclase protein SRP_TPR_like PF17004.5 OQS02908.1 - 0.69 10.0 13.8 0.1 12.6 0.4 3.6 2 2 0 3 3 3 0 Putative TPR-like repeat CDC45 PF02724.14 OQS02908.1 - 5.9 5.1 11.4 1.9 6.7 8.4 1.6 2 0 0 2 2 2 0 CDC45-like protein ATG16 PF08614.11 OQS02908.1 - 8.1 6.6 19.8 0.076 13.2 0.7 3.8 4 0 0 4 4 2 0 Autophagy protein 16 (ATG16) PI-PLC-X PF00388.19 OQS02909.1 - 3.4e-59 198.6 0.0 6.5e-59 197.7 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.19 OQS02909.1 - 3.6e-34 117.6 0.0 7.7e-34 116.5 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain C2 PF00168.30 OQS02909.1 - 8.5e-14 51.7 0.0 2.2e-13 50.4 0.0 1.7 2 0 0 2 2 1 1 C2 domain EF-hand_1 PF00036.32 OQS02909.1 - 2.4e-08 32.9 0.1 0.00039 19.8 0.2 2.7 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 OQS02909.1 - 5.1e-08 33.3 0.1 2.1e-07 31.3 0.1 2.2 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.6 OQS02909.1 - 2.1e-06 27.0 0.7 0.034 13.7 0.1 2.5 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 OQS02909.1 - 4.8e-05 23.0 0.1 0.078 12.9 0.0 2.8 2 0 0 2 2 2 2 EF-hand domain SPARC_Ca_bdg PF10591.9 OQS02909.1 - 0.0022 18.3 0.0 0.0045 17.3 0.0 1.5 1 0 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_8 PF13833.6 OQS02909.1 - 0.0031 17.3 0.2 0.14 12.0 0.2 2.6 2 0 0 2 2 2 1 EF-hand domain pair PH PF00169.29 OQS02909.1 - 0.011 16.2 0.0 0.037 14.5 0.0 2.0 1 0 0 1 1 1 0 PH domain EF-hand_4 PF12763.7 OQS02909.1 - 0.074 13.0 0.1 0.25 11.3 0.1 1.9 1 0 0 1 1 1 0 Cytoskeletal-regulatory complex EF hand PH_12 PF16457.5 OQS02909.1 - 0.096 13.2 0.0 0.25 11.9 0.0 1.7 1 0 0 1 1 1 0 Pleckstrin homology domain Ricin_B_lectin PF00652.22 OQS02910.1 - 7.5e-21 74.7 9.5 7.7e-15 55.3 4.4 2.2 2 0 0 2 2 2 2 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.6 OQS02910.1 - 2.5e-08 34.5 12.0 0.002 18.8 0.6 3.6 3 1 1 4 4 4 3 Ricin-type beta-trefoil lectin domain-like CDtoxinA PF03498.14 OQS02910.1 - 2.5e-05 23.9 1.6 0.0058 16.2 0.4 2.4 2 0 0 2 2 2 2 Cytolethal distending toxin A/C domain Peptidase_S10 PF00450.22 OQS02911.1 - 4.8e-124 415.0 0.1 5.5e-124 414.8 0.1 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase FUSC PF04632.12 OQS02911.1 - 0.17 10.4 0.1 0.26 9.8 0.1 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family Ecotin PF03974.13 OQS02912.1 - 0.017 15.1 0.0 0.03 14.3 0.0 1.5 1 0 0 1 1 1 0 Ecotin RCC1 PF00415.18 OQS02913.1 - 3.6e-60 200.4 24.9 5.3e-15 55.8 0.1 8.0 7 2 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat RabGAP-TBC PF00566.18 OQS02913.1 - 2.8e-44 151.3 0.8 6.7e-44 150.1 0.1 1.9 2 0 0 2 2 2 1 Rab-GTPase-TBC domain RCC1_2 PF13540.6 OQS02913.1 - 6.5e-37 124.6 26.5 9.8e-10 38.0 0.2 7.3 7 0 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat PX PF00787.24 OQS02913.1 - 0.014 15.4 0.2 0.06 13.3 0.1 2.1 2 0 0 2 2 2 0 PX domain DUF4116 PF13475.6 OQS02913.1 - 0.16 11.7 0.0 0.46 10.3 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4116) Asp PF00026.23 OQS02916.1 - 1.1e-65 222.2 0.0 1.3e-65 221.9 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 OQS02916.1 - 7.4e-13 49.1 0.0 5e-06 26.9 0.0 2.6 1 1 1 2 2 2 2 Xylanase inhibitor N-terminal gag-asp_proteas PF13975.6 OQS02916.1 - 0.00095 19.7 0.0 0.018 15.6 0.0 2.3 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 OQS02916.1 - 0.001 19.7 0.6 0.045 14.4 0.1 2.9 2 1 0 2 2 2 1 Aspartyl protease TAXi_C PF14541.6 OQS02916.1 - 0.0032 17.2 0.1 0.033 14.0 0.0 2.1 1 1 1 2 2 2 1 Xylanase inhibitor C-terminal Myb_DNA-binding PF00249.31 OQS02917.1 - 1.9e-31 108.0 3.5 4.1e-16 58.9 1.7 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OQS02917.1 - 7e-27 93.5 1.0 1.9e-18 66.5 0.1 3.0 2 1 1 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OQS02917.1 - 1.2e-08 34.7 1.0 0.00014 21.7 0.1 3.0 1 1 1 2 2 2 2 Myb DNA-binding like SANT_DAMP1_like PF16282.5 OQS02917.1 - 4e-06 26.9 2.7 0.016 15.4 0.1 3.2 3 0 0 3 3 3 2 SANT/Myb-like domain of DAMP1 SLIDE PF09111.10 OQS02917.1 - 0.02 14.9 2.6 0.48 10.5 0.0 3.1 2 1 1 3 3 3 0 SLIDE DUF383 PF04063.14 OQS02918.1 - 6.7e-37 127.0 0.2 2.1e-36 125.4 0.0 1.9 3 0 0 3 3 3 1 Domain of unknown function (DUF383) DUF384 PF04064.13 OQS02918.1 - 1.5e-20 72.8 0.2 1.5e-20 72.8 0.2 3.3 3 0 0 3 3 3 1 Domain of unknown function (DUF384) Neurochondrin PF05536.11 OQS02918.1 - 0.0038 15.7 0.2 0.44 8.9 0.0 2.7 2 1 1 3 3 3 2 Neurochondrin Arm PF00514.23 OQS02918.1 - 0.0079 16.2 7.4 0.061 13.4 0.2 4.5 5 0 0 5 5 5 1 Armadillo/beta-catenin-like repeat Adaptin_N PF01602.20 OQS02918.1 - 0.023 13.3 1.3 0.45 9.0 0.0 2.6 3 1 0 3 3 3 0 Adaptin N terminal region HEAT PF02985.22 OQS02918.1 - 0.75 10.2 3.8 4.3 7.9 0.3 3.6 4 0 0 4 4 4 0 HEAT repeat AAA PF00004.29 OQS02919.1 - 1.7e-98 326.2 0.0 2.7e-48 163.8 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 OQS02919.1 - 2e-24 85.1 12.6 2.1e-12 46.6 0.7 3.3 3 1 0 3 3 2 2 AAA+ lid domain CDC48_N PF02359.18 OQS02919.1 - 5.2e-21 74.6 0.9 1.2e-20 73.5 0.4 1.9 2 0 0 2 2 1 1 Cell division protein 48 (CDC48), N-terminal domain RuvB_N PF05496.12 OQS02919.1 - 3e-14 53.1 0.0 6.8e-06 25.9 0.0 2.8 2 1 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain CDC48_2 PF02933.17 OQS02919.1 - 5.1e-14 51.8 0.0 1.2e-13 50.6 0.0 1.7 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 AAA_2 PF07724.14 OQS02919.1 - 2.1e-12 47.5 0.0 3.5e-06 27.2 0.0 2.8 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 OQS02919.1 - 8.9e-12 45.7 4.2 0.00038 20.9 0.0 4.6 3 2 1 4 4 4 2 AAA ATPase domain AAA_33 PF13671.6 OQS02919.1 - 3.7e-11 43.4 0.0 5.5e-05 23.4 0.0 3.0 3 0 0 3 3 2 2 AAA domain AAA_5 PF07728.14 OQS02919.1 - 5.1e-11 42.7 0.1 1.3e-05 25.2 0.0 3.3 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 OQS02919.1 - 1.2e-10 41.8 0.4 0.021 15.1 0.0 4.9 3 2 1 4 4 4 2 AAA domain TIP49 PF06068.13 OQS02919.1 - 1.3e-08 34.4 0.1 0.00068 18.9 0.0 2.4 2 0 0 2 2 2 2 TIP49 P-loop domain AAA_14 PF13173.6 OQS02919.1 - 4.1e-08 33.3 0.0 0.0025 17.9 0.0 2.9 3 0 0 3 3 3 2 AAA domain Vps4_C PF09336.10 OQS02919.1 - 2.1e-07 30.8 0.3 2e-06 27.7 0.1 2.4 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain AAA_18 PF13238.6 OQS02919.1 - 3.4e-07 30.8 0.0 0.039 14.5 0.0 2.9 2 0 0 2 2 2 2 AAA domain Mg_chelatase PF01078.21 OQS02919.1 - 4.7e-07 29.4 0.2 0.034 13.5 0.0 2.8 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.22 OQS02919.1 - 1.2e-06 28.8 0.0 0.018 15.4 0.0 2.7 2 0 0 2 2 2 2 RNA helicase IstB_IS21 PF01695.17 OQS02919.1 - 3.7e-06 26.8 0.1 0.071 12.8 0.0 2.8 2 1 0 2 2 2 2 IstB-like ATP binding protein AAA_25 PF13481.6 OQS02919.1 - 6.6e-06 25.8 0.3 1.4 8.4 0.0 3.7 2 1 0 3 3 3 1 AAA domain Viral_helicase1 PF01443.18 OQS02919.1 - 7.1e-06 25.9 0.0 0.0065 16.2 0.0 3.2 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase ATPase PF06745.13 OQS02919.1 - 1e-05 25.0 0.1 1.8 7.9 0.0 3.4 3 0 0 3 3 3 1 KaiC AAA_7 PF12775.7 OQS02919.1 - 1.1e-05 25.0 0.0 0.068 12.7 0.0 2.8 2 1 0 2 2 2 2 P-loop containing dynein motor region ATPase_2 PF01637.18 OQS02919.1 - 1.1e-05 25.5 0.1 0.15 12.0 0.0 2.9 2 1 0 2 2 2 2 ATPase domain predominantly from Archaea AAA_17 PF13207.6 OQS02919.1 - 1.6e-05 25.3 0.0 0.11 13.0 0.0 2.9 2 0 0 2 2 2 2 AAA domain Bac_DnaA PF00308.18 OQS02919.1 - 2.5e-05 24.2 0.0 0.18 11.6 0.0 2.9 3 0 0 3 3 3 2 Bacterial dnaA protein AAA_28 PF13521.6 OQS02919.1 - 2.9e-05 24.4 0.2 0.17 12.1 0.0 2.9 3 0 0 3 3 2 2 AAA domain AAA_24 PF13479.6 OQS02919.1 - 3.6e-05 23.6 0.0 0.18 11.5 0.0 3.1 3 0 0 3 3 3 2 AAA domain TsaE PF02367.17 OQS02919.1 - 4.4e-05 23.5 0.0 0.26 11.3 0.0 2.7 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE NACHT PF05729.12 OQS02919.1 - 5.6e-05 23.1 0.0 0.87 9.5 0.0 3.7 3 1 0 4 4 4 2 NACHT domain ABC_tran PF00005.27 OQS02919.1 - 6.6e-05 23.4 0.0 0.36 11.3 0.0 3.1 2 1 0 2 2 2 2 ABC transporter Sigma54_activat PF00158.26 OQS02919.1 - 8.9e-05 22.2 0.0 0.64 9.7 0.0 3.2 2 1 0 2 2 2 2 Sigma-54 interaction domain Zeta_toxin PF06414.12 OQS02919.1 - 0.00015 21.1 0.0 0.69 9.2 0.0 2.7 2 0 0 2 2 2 2 Zeta toxin NB-ARC PF00931.22 OQS02919.1 - 0.00021 20.6 0.0 0.33 10.1 0.0 2.4 2 0 0 2 2 2 2 NB-ARC domain Parvo_NS1 PF01057.17 OQS02919.1 - 0.00023 20.3 0.0 0.38 9.8 0.0 2.2 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 Cytidylate_kin2 PF13189.6 OQS02919.1 - 0.00035 20.8 0.0 0.33 11.1 0.0 2.6 2 0 0 2 2 2 1 Cytidylate kinase-like family Sigma54_activ_2 PF14532.6 OQS02919.1 - 0.00082 19.5 0.0 0.44 10.7 0.0 2.7 2 0 0 2 2 2 1 Sigma-54 interaction domain ResIII PF04851.15 OQS02919.1 - 0.0012 18.9 0.0 0.1 12.6 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_3 PF07726.11 OQS02919.1 - 0.0017 18.2 0.0 2.4 8.0 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) DUF815 PF05673.13 OQS02919.1 - 0.0018 17.5 0.0 0.43 9.7 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF815) DUF2075 PF09848.9 OQS02919.1 - 0.0023 17.2 0.0 1 8.6 0.0 2.4 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) NTPase_1 PF03266.15 OQS02919.1 - 0.0033 17.3 0.8 2.7 7.9 0.0 3.9 3 1 1 4 4 4 1 NTPase PhoH PF02562.16 OQS02919.1 - 0.0038 16.7 2.1 1.4 8.4 0.0 2.9 3 0 0 3 3 3 1 PhoH-like protein AAA_11 PF13086.6 OQS02919.1 - 0.0075 16.1 0.3 5.6 6.7 0.0 3.0 3 0 0 3 3 3 0 AAA domain Rad17 PF03215.15 OQS02919.1 - 0.0088 16.0 0.0 1.8 8.4 0.0 2.6 2 1 0 2 2 2 1 Rad17 P-loop domain AAA_19 PF13245.6 OQS02919.1 - 0.012 16.0 0.9 7.5 6.9 0.1 3.4 3 1 1 4 4 2 0 AAA domain SKI PF01202.22 OQS02919.1 - 0.019 15.1 0.0 8.6 6.5 0.0 2.9 2 0 0 2 2 2 0 Shikimate kinase AAA_30 PF13604.6 OQS02919.1 - 0.024 14.4 0.7 6.7 6.4 0.1 3.0 3 0 0 3 3 3 0 AAA domain Cytidylate_kin PF02224.18 OQS02919.1 - 0.03 14.1 0.0 7.3 6.3 0.0 2.6 2 0 0 2 2 2 0 Cytidylate kinase Zot PF05707.12 OQS02919.1 - 0.055 13.1 0.0 1.3 8.6 0.0 2.7 2 1 0 2 2 2 0 Zonular occludens toxin (Zot) TniB PF05621.11 OQS02919.1 - 0.077 12.4 0.0 16 4.9 0.0 3.3 3 0 0 3 3 3 0 Bacterial TniB protein AAA_29 PF13555.6 OQS02919.1 - 0.098 12.4 0.0 7.2 6.4 0.0 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain KAP_NTPase PF07693.14 OQS02919.1 - 0.11 11.7 0.2 2.8 7.1 0.0 2.9 2 2 1 4 4 4 0 KAP family P-loop domain PduV-EutP PF10662.9 OQS02919.1 - 0.13 12.0 0.0 5.9 6.6 0.0 2.8 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation DapH_N PF08503.10 OQS02920.1 - 0.04 14.1 0.1 0.3 11.3 0.1 2.6 1 1 0 1 1 1 0 Tetrahydrodipicolinate succinyltransferase N-terminal Zein PF01559.16 OQS02920.1 - 1.1 8.7 9.2 1.4 8.5 4.0 2.3 2 0 0 2 2 2 0 Zein seed storage protein Imm6 PF14434.6 OQS02920.1 - 8.7 6.3 13.0 0.09 12.7 1.8 2.8 3 0 0 3 3 3 0 Immunity protein Imm6 Presenilin PF01080.17 OQS02921.1 - 8.6e-95 317.8 16.3 1.5e-94 317.0 16.3 1.3 1 1 0 1 1 1 1 Presenilin DUF2207 PF09972.9 OQS02921.1 - 0.14 10.9 6.3 1.5 7.5 0.1 2.4 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) Sod_Fe_N PF00081.22 OQS02922.1 - 0.11 13.0 0.1 0.37 11.3 0.1 1.9 1 0 0 1 1 1 0 Iron/manganese superoxide dismutases, alpha-hairpin domain HEAT PF02985.22 OQS02923.1 - 9.9e-19 65.8 8.8 1.1e-06 28.4 0.0 9.3 10 0 0 10 10 10 3 HEAT repeat HEAT_EZ PF13513.6 OQS02923.1 - 2.2e-18 66.3 6.3 3.7e-11 43.3 0.0 8.1 9 1 1 10 10 9 2 HEAT-like repeat HEAT_2 PF13646.6 OQS02923.1 - 1.3e-09 38.3 2.6 0.0017 18.7 0.0 7.3 6 1 1 7 7 7 1 HEAT repeats MMS19_C PF12460.8 OQS02923.1 - 1.5e-07 30.9 0.0 0.0085 15.2 0.0 4.9 2 1 3 5 5 5 2 RNAPII transcription regulator C-terminal IBN_N PF03810.19 OQS02923.1 - 2e-07 30.8 0.7 0.00035 20.4 0.1 3.8 3 0 0 3 3 3 1 Importin-beta N-terminal domain Arm PF00514.23 OQS02923.1 - 1.1e-06 28.5 7.1 0.00039 20.4 0.0 6.3 7 0 0 7 7 7 1 Armadillo/beta-catenin-like repeat DUF3385 PF11865.8 OQS02923.1 - 2.4e-05 24.3 2.9 3.8 7.4 0.0 5.8 3 3 3 6 6 6 1 Domain of unknown function (DUF3385) Cnd1 PF12717.7 OQS02923.1 - 3.2e-05 24.0 0.6 0.0072 16.4 0.0 3.4 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 OQS02923.1 - 9.5e-05 21.1 0.0 0.34 9.4 0.0 4.1 3 3 1 4 4 4 1 Adaptin N terminal region Vac14_Fab1_bd PF12755.7 OQS02923.1 - 0.0002 21.9 8.9 9.4 6.9 0.9 7.9 7 4 2 10 10 9 1 Vacuolar 14 Fab1-binding region Cnd3 PF12719.7 OQS02923.1 - 0.0009 18.5 0.1 0.011 14.9 0.1 2.8 2 0 0 2 2 2 1 Nuclear condensing complex subunits, C-term domain CLASP_N PF12348.8 OQS02923.1 - 0.0011 18.6 0.0 1.4 8.4 0.0 3.6 2 2 0 2 2 2 2 CLASP N terminal Sec7_N PF12783.7 OQS02923.1 - 0.016 15.1 0.1 7.2 6.5 0.1 3.7 3 0 0 3 3 3 0 Guanine nucleotide exchange factor in Golgi transport N-terminal Fanconi_A_N PF15865.5 OQS02923.1 - 0.037 13.4 0.6 0.085 12.2 0.2 1.8 2 0 0 2 2 2 0 Fanconi anaemia group A protein N terminus Kazal_2 PF07648.15 OQS02924.1 - 8.2e-17 61.1 17.7 5.2e-09 36.1 6.1 2.3 2 0 0 2 2 2 2 Kazal-type serine protease inhibitor domain Kazal_1 PF00050.21 OQS02924.1 - 3.4e-16 59.0 16.9 3.1e-08 33.5 4.5 2.5 2 1 0 2 2 2 2 Kazal-type serine protease inhibitor domain Methyltr_RsmB-F PF01189.17 OQS02925.1 - 1.9e-35 122.3 0.0 2.7e-35 121.8 0.0 1.2 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F FtsJ PF01728.19 OQS02925.1 - 3.7e-05 23.9 0.1 5.9e-05 23.3 0.1 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase Ubie_methyltran PF01209.18 OQS02925.1 - 0.11 11.8 0.0 0.19 11.1 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family SidE PF12252.8 OQS02926.1 - 0.056 11.0 0.0 0.074 10.6 0.0 1.0 1 0 0 1 1 1 0 Dot/Icm substrate protein sCache_like PF16736.5 OQS02926.1 - 0.092 12.8 0.1 0.17 12.0 0.1 1.4 1 0 0 1 1 1 0 Single Cache-like DmsC PF04976.12 OQS02926.1 - 0.092 12.2 0.2 0.13 11.7 0.2 1.1 1 0 0 1 1 1 0 DMSO reductase anchor subunit (DmsC) Flavoprotein PF02441.19 OQS02927.1 - 7.6e-47 159.0 0.1 9e-47 158.8 0.1 1.0 1 0 0 1 1 1 1 Flavoprotein MCM PF00493.23 OQS02928.1 - 2.7e-97 324.3 0.0 1e-96 322.4 0.0 1.8 2 0 0 2 2 2 1 MCM P-loop domain MCM_OB PF17207.3 OQS02928.1 - 4.5e-38 129.9 0.1 1.3e-37 128.5 0.1 1.8 2 0 0 2 2 2 1 MCM OB domain MCM_lid PF17855.1 OQS02928.1 - 4.3e-28 97.6 1.3 9.5e-28 96.5 1.3 1.6 1 0 0 1 1 1 1 MCM AAA-lid domain HSF_DNA-bind PF00447.17 OQS02928.1 - 9.9e-20 71.0 0.4 2.3e-19 69.8 0.4 1.6 1 0 0 1 1 1 1 HSF-type DNA-binding MCM_N PF14551.6 OQS02928.1 - 2.2e-11 44.3 0.7 1.1e-10 42.0 0.2 2.4 2 0 0 2 2 2 1 MCM N-terminal domain AAA_5 PF07728.14 OQS02928.1 - 4.2e-08 33.3 0.0 4.3e-07 30.0 0.0 2.7 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 OQS02928.1 - 1.8e-06 27.5 0.1 0.00022 20.7 0.0 2.4 1 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 OQS02928.1 - 0.00081 19.3 0.0 0.0032 17.3 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 OQS02928.1 - 0.0038 16.9 0.0 0.052 13.3 0.0 2.3 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_16 PF13191.6 OQS02928.1 - 0.048 14.0 0.2 0.26 11.6 0.1 2.2 1 1 0 2 2 2 0 AAA ATPase domain zf-HC5HC2H_2 PF13832.6 OQS02928.1 - 0.11 12.7 0.7 0.3 11.3 0.7 1.7 1 0 0 1 1 1 0 PHD-zinc-finger like domain C1_1 PF00130.22 OQS02928.1 - 9.6 6.2 7.9 13 5.8 0.3 3.0 3 0 0 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) DFRP_C PF16543.5 OQS02929.1 - 1.1e-21 77.2 2.7 1.1e-21 77.2 2.7 3.9 3 1 1 4 4 4 1 DRG Family Regulatory Proteins, Tma46 zf-CCCH_4 PF18044.1 OQS02929.1 - 1.5e-05 24.7 8.7 0.00016 21.3 0.8 3.2 3 0 0 3 3 3 1 CCCH-type zinc finger zf-CCCH PF00642.24 OQS02929.1 - 3.4e-05 23.6 0.5 3.4e-05 23.6 0.5 2.6 3 0 0 3 3 3 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 OQS02929.1 - 0.0093 16.0 4.9 0.0093 16.0 4.9 3.3 3 0 0 3 3 3 1 Zinc finger domain Torus PF16131.5 OQS02929.1 - 0.017 15.8 20.8 0.81 10.4 9.3 4.3 2 1 1 3 3 3 0 Torus domain zf-CCCH_3 PF15663.5 OQS02929.1 - 0.035 14.3 1.0 0.035 14.3 1.0 2.9 2 1 1 3 3 3 0 Zinc-finger containing family zf-CCCH_2 PF14608.6 OQS02929.1 - 2.4 8.7 12.8 2.4 8.8 4.2 2.9 2 1 0 2 2 2 0 RNA-binding, Nab2-type zinc finger UQ_con PF00179.26 OQS02930.1 - 1e-19 70.6 0.0 2.3e-19 69.5 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme DUF1610 PF07754.11 OQS02930.1 - 0.058 13.4 0.0 0.21 11.6 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1610) RWD PF05773.22 OQS02930.1 - 0.076 13.3 0.0 0.14 12.4 0.0 1.5 1 0 0 1 1 1 0 RWD domain Zf_RING PF16744.5 OQS02930.1 - 0.17 12.0 0.0 0.28 11.3 0.0 1.3 1 0 0 1 1 1 0 KIAA1045 RING finger Acyl-CoA_dh_1 PF00441.24 OQS02931.1 - 2e-44 151.4 1.6 2.2e-44 151.3 0.5 1.6 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 OQS02931.1 - 3.9e-32 111.3 0.0 2.2e-31 108.9 0.0 2.1 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 OQS02931.1 - 2.8e-25 88.3 0.0 5.5e-25 87.4 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 OQS02931.1 - 9.9e-19 67.9 0.1 1.8e-18 67.1 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain AFG1_ATPase PF03969.16 OQS02931.1 - 0.068 12.1 0.0 0.11 11.4 0.0 1.2 1 0 0 1 1 1 0 AFG1-like ATPase BT1 PF03092.16 OQS02932.1 - 4.8e-13 48.2 2.6 1.1e-12 47.0 0.6 2.2 2 0 0 2 2 2 1 BT1 family PUCC PF03209.15 OQS02932.1 - 0.00082 18.5 1.6 0.00082 18.5 1.6 2.2 2 1 0 2 2 2 1 PUCC protein MFS_1 PF07690.16 OQS02932.1 - 1.7 7.5 39.1 1.1 8.0 33.4 3.0 1 1 1 2 2 2 0 Major Facilitator Superfamily Kinesin PF00225.23 OQS02933.1 - 2.1e-70 237.3 2.3 3.3e-70 236.6 2.3 1.3 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 OQS02933.1 - 1.5e-13 50.9 0.3 4.6e-13 49.4 0.1 1.9 2 0 0 2 2 2 1 Microtubule binding AAA_11 PF13086.6 OQS02933.1 - 0.0018 18.1 0.5 0.0031 17.3 0.5 1.5 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 OQS02933.1 - 0.004 17.4 0.3 0.034 14.4 0.3 2.3 1 1 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 OQS02933.1 - 0.0081 16.5 0.0 0.023 15.1 0.0 1.9 1 0 0 1 1 1 1 RNA helicase Flavi_glycoprot PF00869.20 OQS02933.1 - 0.011 14.9 0.1 0.02 14.2 0.1 1.4 1 0 0 1 1 1 0 Flavivirus glycoprotein, central and dimerisation domains AAA_7 PF12775.7 OQS02933.1 - 0.014 14.9 0.0 0.036 13.6 0.0 1.7 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_24 PF13479.6 OQS02933.1 - 0.022 14.5 0.0 0.061 13.0 0.0 1.9 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 OQS02933.1 - 0.037 13.3 0.2 0.085 12.1 0.2 1.6 1 0 0 1 1 1 0 Zeta toxin AAA_30 PF13604.6 OQS02933.1 - 0.038 13.7 0.0 0.07 12.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 OQS02933.1 - 0.045 13.7 0.0 0.1 12.6 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE SRP54 PF00448.22 OQS02933.1 - 0.051 13.2 0.0 0.094 12.3 0.0 1.6 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_16 PF13191.6 OQS02933.1 - 0.055 13.9 0.2 0.15 12.4 0.2 1.9 1 1 0 1 1 1 0 AAA ATPase domain DUF87 PF01935.17 OQS02933.1 - 0.057 13.5 0.2 0.37 10.8 0.0 2.4 2 0 0 2 2 2 0 Helicase HerA, central domain Nup88 PF10168.9 OQS02934.1 - 1.3e-09 36.5 16.2 3.3e-07 28.6 11.3 2.8 3 0 0 3 3 3 2 Nuclear pore component Spc7 PF08317.11 OQS02934.1 - 0.0066 15.4 5.8 0.015 14.2 5.8 1.6 1 0 0 1 1 1 1 Spc7 kinetochore protein TolA_bind_tri PF16331.5 OQS02934.1 - 0.2 11.7 6.7 0.53 10.4 1.1 2.7 1 1 1 2 2 2 0 TolA binding protein trimerisation DUF4988 PF16378.5 OQS02934.1 - 0.45 10.2 2.9 0.39 10.4 0.2 2.3 3 0 0 3 3 3 0 Domain of unknown function PEARLI-4 PF05278.12 OQS02934.1 - 4.3 6.8 8.4 3.4 7.2 0.1 2.9 2 1 1 3 3 3 0 Arabidopsis phospholipase-like protein (PEARLI 4) DUF4472 PF14739.6 OQS02934.1 - 5.5 7.8 8.3 1.5 9.6 0.9 3.2 2 1 2 4 4 4 0 Domain of unknown function (DUF4472) VPS28 PF03997.12 OQS02935.1 - 3.6e-64 215.9 0.1 4.5e-64 215.6 0.1 1.1 1 0 0 1 1 1 1 VPS28 protein Helicase_C_3 PF13625.6 OQS02935.1 - 0.034 14.3 0.8 1.5 8.9 0.1 2.4 1 1 1 2 2 2 0 Helicase conserved C-terminal domain NAD_binding_4 PF07993.12 OQS02935.1 - 0.08 12.1 0.0 0.12 11.5 0.0 1.2 1 0 0 1 1 1 0 Male sterility protein Dynein_C PF18199.1 OQS02936.1 - 0.02 14.1 0.1 0.035 13.3 0.1 1.4 1 0 0 1 1 1 0 Dynein heavy chain C-terminal domain zf-C4pol PF14260.6 OQS02936.1 - 0.24 11.9 3.8 0.22 12.0 1.2 2.3 2 0 0 2 2 2 0 C4-type zinc-finger of DNA polymerase delta VWC PF00093.18 OQS02936.1 - 0.45 10.9 0.1 0.45 10.9 0.1 2.6 4 0 0 4 4 4 0 von Willebrand factor type C domain Linker_histone PF00538.19 OQS02937.1 - 0.027 14.8 0.6 0.055 13.8 0.2 1.8 1 1 0 1 1 1 0 linker histone H1 and H5 family DYW_deaminase PF14432.6 OQS02938.1 - 4.8e-15 55.6 0.1 7.6e-15 54.9 0.1 1.3 1 0 0 1 1 1 1 DYW family of nucleic acid deaminases MatE PF01554.18 OQS02940.1 - 4e-56 189.1 33.8 1.3e-28 99.7 10.8 2.2 2 0 0 2 2 2 2 MatE Polysacc_synt_C PF14667.6 OQS02940.1 - 8.3e-06 25.9 10.5 8.3e-06 25.9 10.5 4.2 2 1 3 5 5 5 1 Polysaccharide biosynthesis C-terminal domain DUF3311 PF11755.8 OQS02940.1 - 0.41 10.6 4.4 3.2 7.8 0.0 3.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3311) ApoA-II PF04711.13 OQS02941.1 - 0.016 15.3 0.7 0.048 13.8 0.1 2.0 2 0 0 2 2 2 0 Apolipoprotein A-II (ApoA-II) RIIa PF02197.17 OQS02941.1 - 0.034 13.8 0.3 0.5 10.1 0.0 2.4 2 0 0 2 2 2 0 Regulatory subunit of type II PKA R-subunit DUF1368 PF07112.11 OQS02941.1 - 0.051 12.4 0.1 0.073 11.9 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1368) ThiF PF00899.21 OQS02941.1 - 0.068 12.5 0.1 2.9 7.2 0.0 2.1 2 0 0 2 2 2 0 ThiF family Dpy-30 PF05186.13 OQS02941.1 - 0.082 12.6 0.0 5 6.9 0.0 2.2 2 0 0 2 2 2 0 Dpy-30 motif Linker_histone PF00538.19 OQS02942.1 - 0.016 15.6 0.8 0.029 14.7 0.3 1.9 1 1 0 1 1 1 0 linker histone H1 and H5 family Zn-ribbon_8 PF09723.10 OQS02942.1 - 0.62 10.2 6.8 0.69 10.1 0.0 2.4 2 0 0 2 2 2 0 Zinc ribbon domain Mpp10 PF04006.12 OQS02943.1 - 4.4e-140 468.1 75.5 6.2e-140 467.6 75.5 1.2 1 0 0 1 1 1 1 Mpp10 protein EF-hand_1 PF00036.32 OQS02944.1 - 1.4e-05 24.3 4.5 0.58 9.8 0.0 3.6 3 0 0 3 3 3 3 EF hand EF-hand_5 PF13202.6 OQS02944.1 - 4.2e-05 22.9 11.1 0.51 9.9 0.7 3.6 3 0 0 3 3 3 3 EF hand VCBS PF13517.6 OQS02944.1 - 9.4e-05 22.9 2.5 0.43 11.2 0.1 3.6 3 0 0 3 3 3 1 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella EF-hand_6 PF13405.6 OQS02944.1 - 0.0029 17.4 4.2 4.5 7.5 0.3 3.6 3 0 0 3 3 3 2 EF-hand domain EF-hand_7 PF13499.6 OQS02944.1 - 0.013 15.9 2.6 6.1 7.4 0.0 3.2 2 1 0 2 2 2 0 EF-hand domain pair EF-hand_8 PF13833.6 OQS02944.1 - 0.25 11.2 3.2 68 3.4 0.0 3.6 3 0 0 3 3 3 0 EF-hand domain pair Dockerin_1 PF00404.18 OQS02944.1 - 3 8.1 8.7 35 4.7 1.3 3.3 2 1 1 3 3 3 0 Dockerin type I domain Abhydrolase_6 PF12697.7 OQS02945.1 - 9.3e-18 65.6 0.2 1.5e-12 48.6 0.1 2.1 1 1 0 2 2 2 2 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 OQS02945.1 - 1.4e-16 60.5 1.0 1.9e-12 47.0 0.6 2.9 2 1 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 OQS02945.1 - 1.5e-14 54.3 0.1 8.3e-12 45.3 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold DUF1057 PF06342.12 OQS02945.1 - 3.2e-10 39.5 0.1 7.9e-09 35.0 0.0 2.1 2 0 0 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF1057) Thioesterase PF00975.20 OQS02945.1 - 1.7e-08 34.9 0.0 1.1e-05 25.7 0.0 2.3 2 0 0 2 2 2 2 Thioesterase domain Esterase PF00756.20 OQS02945.1 - 6.3e-08 32.6 0.1 0.0022 17.7 0.0 2.3 2 0 0 2 2 2 2 Putative esterase UPF0227 PF05728.12 OQS02945.1 - 2.2e-06 27.7 0.3 0.081 12.9 0.0 2.5 2 1 0 2 2 2 2 Uncharacterised protein family (UPF0227) PGAP1 PF07819.13 OQS02945.1 - 2.1e-05 24.4 0.9 0.024 14.4 0.4 3.2 2 1 0 2 2 2 1 PGAP1-like protein Ser_hydrolase PF06821.13 OQS02945.1 - 2.6e-05 24.1 0.1 0.036 13.9 0.0 3.1 3 0 0 3 3 3 1 Serine hydrolase Chlorophyllase2 PF12740.7 OQS02945.1 - 0.00018 20.5 0.2 0.0062 15.5 0.1 2.2 2 0 0 2 2 2 1 Chlorophyllase enzyme Lipase_3 PF01764.25 OQS02945.1 - 0.00026 20.8 0.1 0.42 10.5 0.0 2.3 2 0 0 2 2 2 2 Lipase (class 3) LIDHydrolase PF10230.9 OQS02945.1 - 0.00029 20.5 0.1 0.78 9.2 0.0 2.5 3 0 0 3 3 3 2 Lipid-droplet associated hydrolase DUF676 PF05057.14 OQS02945.1 - 0.0018 17.8 0.0 0.064 12.8 0.0 2.2 2 0 0 2 2 2 1 Putative serine esterase (DUF676) Acyl_transf_1 PF00698.21 OQS02945.1 - 0.0023 17.5 0.2 0.58 9.6 0.0 2.1 2 0 0 2 2 2 2 Acyl transferase domain Palm_thioest PF02089.15 OQS02945.1 - 0.0028 17.5 0.0 0.33 10.7 0.0 2.2 2 0 0 2 2 2 1 Palmitoyl protein thioesterase Abhydrolase_2 PF02230.16 OQS02945.1 - 0.023 14.5 0.0 0.061 13.1 0.0 1.6 1 1 0 1 1 1 0 Phospholipase/Carboxylesterase DUF915 PF06028.11 OQS02945.1 - 0.026 13.9 0.3 9.1 5.5 0.0 3.1 3 0 0 3 3 3 0 Alpha/beta hydrolase of unknown function (DUF915) Tub PF01167.18 OQS02946.1 - 2.3e-67 227.3 0.0 2.7e-67 227.0 0.0 1.1 1 0 0 1 1 1 1 Tub family zf-RING_2 PF13639.6 OQS02946.1 - 9.9e-08 32.2 8.3 9.9e-08 32.2 8.3 1.9 2 0 0 2 2 2 1 Ring finger domain RINGv PF12906.7 OQS02946.1 - 0.00023 21.2 3.4 0.0006 19.9 3.4 1.7 1 0 0 1 1 1 1 RING-variant domain zf-rbx1 PF12678.7 OQS02946.1 - 0.0004 20.6 5.2 0.0011 19.2 5.2 1.8 1 1 0 1 1 1 1 RING-H2 zinc finger domain DUF3527 PF12043.8 OQS02946.1 - 0.0014 18.3 0.0 0.0024 17.5 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3527) zf-C3HC4_2 PF13923.6 OQS02946.1 - 0.0018 18.0 5.4 0.0084 15.9 5.4 2.1 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 OQS02946.1 - 0.018 14.9 7.9 0.046 13.6 7.9 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OQS02946.1 - 0.095 12.7 5.7 0.24 11.4 5.7 1.7 1 0 0 1 1 1 0 zinc-RING finger domain zf-ANAPC11 PF12861.7 OQS02946.1 - 0.67 10.0 5.3 2 8.5 5.3 1.7 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger HSF_DNA-bind PF00447.17 OQS02947.1 - 3.3e-26 91.7 1.1 7.4e-26 90.6 1.1 1.6 1 0 0 1 1 1 1 HSF-type DNA-binding HAP1_N PF04849.13 OQS02947.1 - 0.089 12.0 7.1 0.17 11.0 7.1 1.4 1 0 0 1 1 1 0 HAP1 N-terminal conserved region AbiEi_4 PF13338.6 OQS02947.1 - 0.14 12.4 0.0 23 5.2 0.0 2.3 2 0 0 2 2 2 0 Transcriptional regulator, AbiEi antitoxin EIAV_Rev PF11129.8 OQS02947.1 - 0.14 12.3 0.4 0.26 11.5 0.4 1.4 1 0 0 1 1 1 0 Rev protein of equine infectious anaemia virus TRAPPC-Trs85 PF12739.7 OQS02947.1 - 0.65 8.9 3.5 0.23 10.4 1.0 1.4 2 0 0 2 2 2 0 ER-Golgi trafficking TRAPP I complex 85 kDa subunit zf-TAZ PF02135.16 OQS02948.1 - 2.6e-10 40.6 14.5 3.4e-10 40.2 14.5 1.2 1 0 0 1 1 1 1 TAZ zinc finger Ins_P5_2-kin PF06090.12 OQS02949.1 - 8.7e-71 239.0 0.0 1.1e-70 238.8 0.0 1.1 1 0 0 1 1 1 1 Inositol-pentakisphosphate 2-kinase Ras PF00071.22 OQS02950.1 - 2.8e-42 144.1 0.0 3.2e-42 143.9 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OQS02950.1 - 4.7e-28 97.8 0.0 9.2e-28 96.9 0.0 1.4 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OQS02950.1 - 6.3e-09 35.5 0.0 7.9e-09 35.2 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family RNA_helicase PF00910.22 OQS02950.1 - 2.4e-05 24.7 0.1 6.1e-05 23.4 0.1 1.7 1 1 0 1 1 1 1 RNA helicase MMR_HSR1 PF01926.23 OQS02950.1 - 0.00018 21.5 0.0 0.00032 20.7 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 OQS02950.1 - 0.00076 19.4 0.2 0.61 10.0 0.0 2.2 1 1 0 2 2 2 2 RsgA GTPase G-alpha PF00503.20 OQS02950.1 - 0.0074 15.5 0.2 1.6 7.8 0.0 2.2 2 0 0 2 2 2 2 G-protein alpha subunit ArgoMid PF16487.5 OQS02950.1 - 0.028 14.7 0.2 0.069 13.4 0.2 1.8 1 1 1 2 2 2 0 Mid domain of argonaute Septin PF00735.18 OQS02950.1 - 0.08 12.2 0.1 0.25 10.6 0.0 1.7 2 0 0 2 2 2 0 Septin NYD-SP28 PF14772.6 OQS02951.1 - 5.9e-05 23.1 3.0 8.1e-05 22.6 3.0 1.2 1 0 0 1 1 1 1 Sperm tail Spc7 PF08317.11 OQS02951.1 - 0.00013 21.0 3.2 0.00014 20.9 3.2 1.0 1 0 0 1 1 1 1 Spc7 kinetochore protein HAP1_N PF04849.13 OQS02951.1 - 0.00072 18.8 1.9 0.00077 18.8 1.9 1.0 1 0 0 1 1 1 1 HAP1 N-terminal conserved region KASH_CCD PF14662.6 OQS02951.1 - 0.0014 18.5 2.8 0.0017 18.2 2.8 1.0 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 or KASH HAUS-augmin3 PF14932.6 OQS02951.1 - 0.0064 16.1 7.4 0.0074 15.9 7.4 1.0 1 0 0 1 1 1 1 HAUS augmin-like complex subunit 3 DUF4201 PF13870.6 OQS02951.1 - 0.0085 15.8 3.7 0.011 15.4 3.7 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4201) Syntaxin-6_N PF09177.11 OQS02951.1 - 0.019 15.5 0.3 0.025 15.1 0.3 1.2 1 0 0 1 1 1 0 Syntaxin 6, N-terminal UPF0242 PF06785.11 OQS02951.1 - 0.036 14.2 3.2 0.045 13.9 3.2 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus FlaC_arch PF05377.11 OQS02951.1 - 0.044 14.2 0.3 0.7 10.3 0.0 2.2 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) DivIC PF04977.15 OQS02951.1 - 0.048 13.4 9.9 0.22 11.3 4.4 2.9 1 1 1 2 2 2 0 Septum formation initiator ZapB PF06005.12 OQS02951.1 - 0.063 13.7 8.5 0.27 11.7 8.5 1.9 1 1 0 1 1 1 0 Cell division protein ZapB HIP1_clath_bdg PF16515.5 OQS02951.1 - 0.082 13.5 4.8 0.11 13.2 2.0 2.0 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 YabA PF06156.13 OQS02951.1 - 0.16 12.6 3.2 0.24 12.0 3.2 1.3 1 1 0 1 1 1 0 Initiation control protein YabA DUF641 PF04859.12 OQS02951.1 - 0.17 12.2 4.5 0.83 10.0 4.6 1.8 1 1 0 1 1 1 0 Plant protein of unknown function (DUF641) CENP-H PF05837.12 OQS02951.1 - 0.19 12.2 6.5 0.24 11.8 6.5 1.1 1 0 0 1 1 1 0 Centromere protein H (CENP-H) Bap31_Bap29_C PF18035.1 OQS02951.1 - 0.19 11.8 3.7 1.2 9.2 0.5 2.3 2 0 0 2 2 2 0 Bap31/Bap29 cytoplasmic coiled-coil domain Cep57_CLD_2 PF14197.6 OQS02951.1 - 0.21 11.7 7.2 2.4 8.3 7.2 2.0 1 1 0 1 1 1 0 Centrosome localisation domain of PPC89 DUF4407 PF14362.6 OQS02951.1 - 0.22 10.9 5.5 0.32 10.3 5.5 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) OmpH PF03938.14 OQS02951.1 - 0.28 11.5 8.3 2 8.8 8.3 1.9 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) HALZ PF02183.18 OQS02951.1 - 0.28 11.5 6.5 0.083 13.1 2.0 2.4 2 1 0 2 2 2 0 Homeobox associated leucine zipper ABC_tran_CTD PF16326.5 OQS02951.1 - 0.36 11.1 6.6 1.5 9.1 1.4 2.2 1 1 1 2 2 2 0 ABC transporter C-terminal domain HR1 PF02185.16 OQS02951.1 - 0.38 10.9 8.1 5.9 7.1 8.1 2.3 1 1 0 1 1 1 0 Hr1 repeat TMF_DNA_bd PF12329.8 OQS02951.1 - 0.41 10.7 7.4 0.94 9.5 0.9 2.1 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding bZIP_2 PF07716.15 OQS02951.1 - 0.56 10.3 10.1 1.8 8.7 0.4 3.0 2 1 1 3 3 3 0 Basic region leucine zipper M PF02370.16 OQS02951.1 - 3.7 8.4 8.0 6.5 7.7 1.3 3.3 3 1 0 3 3 3 0 M protein repeat tRNA-synt_2c PF01411.19 OQS02952.1 - 1.1e-162 542.5 0.0 1.6e-162 541.9 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (A) tRNA_SAD PF07973.14 OQS02952.1 - 5.1e-14 52.1 0.1 1.5e-13 50.6 0.1 1.9 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain SlyX PF04102.12 OQS02952.1 - 0.098 13.3 0.5 0.34 11.5 0.5 1.9 1 0 0 1 1 1 0 SlyX EF-hand_6 PF13405.6 OQS02952.1 - 0.12 12.4 0.0 22 5.3 0.0 3.3 3 0 0 3 3 3 0 EF-hand domain TFIIA_gamma_N PF02268.16 OQS02953.1 - 0.018 15.0 0.0 0.037 14.0 0.0 1.6 1 0 0 1 1 1 0 Transcription initiation factor IIA, gamma subunit, helical domain Poxvirus_B22R PF04395.12 OQS02953.1 - 0.041 13.4 1.2 0.048 13.2 1.2 1.2 1 0 0 1 1 1 0 Poxvirus B22R protein Acetyltransf_2 PF00797.17 OQS02955.1 - 3.6e-09 36.8 0.3 2.2e-08 34.2 0.3 1.9 1 1 0 1 1 1 1 N-acetyltransferase CTP_transf_1 PF01148.20 OQS02956.1 - 4.6e-70 236.4 22.5 6.1e-70 236.0 22.5 1.2 1 0 0 1 1 1 1 Cytidylyltransferase family MFS_1 PF07690.16 OQS02958.1 - 6.5e-35 120.7 32.8 8.4e-35 120.3 30.5 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily DNA_pol_E_B PF04042.16 OQS02959.1 - 1.3e-38 132.5 0.5 1.8e-38 132.0 0.5 1.2 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B Pol_alpha_B_N PF08418.10 OQS02959.1 - 0.0012 18.9 0.0 0.0019 18.2 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase alpha subunit B N-terminal Prominin PF05478.11 OQS02960.1 - 0.0016 16.5 5.7 0.0019 16.2 5.7 1.0 1 0 0 1 1 1 1 Prominin FAM184 PF15665.5 OQS02960.1 - 0.0022 17.8 12.9 0.0022 17.8 12.9 1.9 1 1 1 2 2 2 1 Family with sequence similarity 184, A and B DUF5344 PF17279.2 OQS02960.1 - 0.0071 16.9 5.1 0.2 12.2 0.7 3.1 1 1 2 3 3 3 1 Family of unknown function (DUF5344) TssC PF17541.2 OQS02960.1 - 0.0095 14.8 3.9 0.011 14.6 3.9 1.1 1 0 0 1 1 1 1 Type VI secretion system, TssC, VipB HycH PF07450.11 OQS02960.1 - 0.042 14.2 2.0 0.062 13.7 1.2 1.7 1 1 0 1 1 1 0 Formate hydrogenlyase maturation protein HycH MAM PF00629.23 OQS02960.1 - 0.043 13.7 0.8 0.053 13.5 0.8 1.2 1 0 0 1 1 1 0 MAM domain, meprin/A5/mu Peptidase_S8_N PF16361.5 OQS02960.1 - 0.049 14.1 2.8 0.34 11.4 1.3 2.2 1 1 1 2 2 2 0 N-terminal of Subtilase family AAA_11 PF13086.6 OQS02960.1 - 0.064 13.0 4.7 0.078 12.8 4.7 1.2 1 0 0 1 1 1 0 AAA domain Apolipoprotein PF01442.18 OQS02960.1 - 0.13 12.1 9.5 0.24 11.3 9.5 1.5 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain ATP-synt_E_2 PF08112.11 OQS02960.1 - 0.14 12.4 4.3 0.71 10.2 0.2 2.9 2 1 0 2 2 2 0 ATP synthase epsilon subunit HTH_WhiA PF02650.14 OQS02960.1 - 0.2 12.0 2.3 12 6.3 0.1 2.7 1 1 1 2 2 2 0 WhiA C-terminal HTH domain PMEI PF04043.15 OQS02960.1 - 0.23 11.8 4.2 0.86 9.9 4.2 1.9 1 1 0 1 1 1 0 Plant invertase/pectin methylesterase inhibitor Baculo_PEP_C PF04513.12 OQS02960.1 - 0.36 10.9 3.0 3.3 7.7 1.3 2.3 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1664 PF07889.12 OQS02960.1 - 0.39 10.7 11.9 1.7 8.7 3.0 3.4 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) Exonuc_VII_L PF02601.15 OQS02960.1 - 0.81 9.2 7.8 1.3 8.5 7.8 1.4 1 1 0 1 1 1 0 Exonuclease VII, large subunit CAP_N PF01213.19 OQS02960.1 - 0.97 8.8 5.8 2.8 7.3 2.9 2.0 1 1 1 2 2 2 0 Adenylate cyclase associated (CAP) N terminal Mt_ATP-synt_D PF05873.12 OQS02960.1 - 1.5 8.7 7.2 1.1 9.1 0.7 2.6 1 1 2 3 3 3 0 ATP synthase D chain, mitochondrial (ATP5H) NPV_P10 PF05531.12 OQS02960.1 - 3.6 8.1 6.9 57 4.3 5.6 3.4 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Seryl_tRNA_N PF02403.22 OQS02960.1 - 4.4 7.6 10.4 21 5.4 4.2 3.0 1 1 2 3 3 3 0 Seryl-tRNA synthetase N-terminal domain Tfb2 PF03849.14 OQS02961.1 - 5.1e-117 390.8 1.8 6.3e-117 390.5 1.8 1.1 1 0 0 1 1 1 1 Transcription factor Tfb2 Tfb2_C PF18307.1 OQS02961.1 - 2.7e-22 79.0 0.4 9.9e-21 73.9 0.2 2.7 2 0 0 2 2 2 1 Transcription factor Tfb2 (p52) C-terminal domain Helicase_C_3 PF13625.6 OQS02961.1 - 0.019 15.1 0.0 0.077 13.1 0.0 2.0 2 0 0 2 2 2 0 Helicase conserved C-terminal domain DUF4911 PF16256.5 OQS02961.1 - 0.051 13.5 0.0 9.7 6.3 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4911) MRP-S34 PF16053.5 OQS02962.1 - 4.4e-15 55.5 0.2 6.8e-15 54.9 0.2 1.3 1 0 0 1 1 1 1 Mitochondrial 28S ribosomal protein S34 RBFA PF02033.18 OQS02962.1 - 0.099 13.1 0.0 0.77 10.2 0.0 2.0 1 1 1 2 2 2 0 Ribosome-binding factor A TsaE PF02367.17 OQS02964.1 - 1.1e-30 106.2 0.0 1.2e-30 106.0 0.0 1.1 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE NACHT PF05729.12 OQS02964.1 - 0.00025 21.0 0.0 0.00033 20.6 0.0 1.3 1 0 0 1 1 1 1 NACHT domain Zeta_toxin PF06414.12 OQS02964.1 - 0.0019 17.5 0.0 0.0025 17.1 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin AAA_7 PF12775.7 OQS02964.1 - 0.017 14.7 0.0 0.021 14.3 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_16 PF13191.6 OQS02964.1 - 0.017 15.5 0.0 0.018 15.4 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain AAA PF00004.29 OQS02964.1 - 0.02 15.3 0.0 0.094 13.1 0.0 1.9 1 1 1 2 2 2 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 OQS02964.1 - 0.031 14.7 0.0 0.056 13.8 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_33 PF13671.6 OQS02964.1 - 0.038 14.2 0.0 0.053 13.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 OQS02964.1 - 0.053 13.2 0.0 0.1 12.3 0.0 1.3 1 1 0 1 1 1 0 Sigma-54 interaction domain Roc PF08477.13 OQS02964.1 - 0.068 13.4 0.0 0.12 12.6 0.0 1.5 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase Sigma54_activ_2 PF14532.6 OQS02964.1 - 0.075 13.1 0.0 0.11 12.7 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_22 PF13401.6 OQS02964.1 - 0.084 13.1 0.0 0.13 12.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 OQS02964.1 - 0.18 12.3 0.0 0.19 12.3 0.0 1.3 1 0 0 1 1 1 0 ABC transporter ATPase PF06745.13 OQS02964.1 - 0.18 11.1 0.0 0.22 10.8 0.0 1.3 1 0 0 1 1 1 0 KaiC Sep15_SelM PF08806.11 OQS02965.1 - 1.5e-10 41.1 0.0 2.1e-10 40.6 0.0 1.3 1 0 0 1 1 1 1 Sep15/SelM redox domain TAP_C PF03943.13 OQS02965.1 - 0.014 15.1 0.1 0.029 14.0 0.1 1.6 1 0 0 1 1 1 0 TAP C-terminal domain IL11 PF07400.11 OQS02966.1 - 0.0046 16.6 3.3 0.0046 16.6 3.3 3.4 2 1 2 4 4 4 1 Interleukin 11 Jnk-SapK_ap_N PF09744.9 OQS02966.1 - 0.014 15.6 9.0 0.014 15.6 9.0 2.6 2 1 1 3 3 3 0 JNK_SAPK-associated protein-1 Syntaxin PF00804.25 OQS02966.1 - 0.24 11.0 16.1 0.082 12.6 8.2 2.8 3 0 0 3 3 3 0 Syntaxin DUF1690 PF07956.11 OQS02966.1 - 1.1 9.7 20.0 0.13 12.7 4.8 4.0 2 1 1 4 4 4 0 Protein of Unknown function (DUF1690) DUF2400 PF09674.10 OQS02966.1 - 3.1 7.7 8.3 1.4 8.8 2.4 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF2400) F_actin_bind PF08919.10 OQS02966.1 - 4.4 7.5 8.6 1.9 8.6 2.4 3.3 2 1 0 2 2 2 0 F-actin binding XhlA PF10779.9 OQS02966.1 - 5.1 7.4 6.6 22 5.4 0.0 3.7 3 1 1 4 4 4 0 Haemolysin XhlA Gluconate_2-dh3 PF13618.6 OQS02966.1 - 5.3 7.3 7.2 32 4.8 4.3 2.9 1 1 1 2 2 2 0 Gluconate 2-dehydrogenase subunit 3 Snapin_Pallidin PF14712.6 OQS02966.1 - 6.7 7.2 13.5 18 5.9 0.0 4.3 4 0 0 4 4 4 0 Snapin/Pallidin Myb_DNA-binding PF00249.31 OQS02967.1 - 4.4e-36 122.8 9.4 1.1e-13 51.1 0.8 3.2 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OQS02967.1 - 5e-36 122.8 5.9 9.1e-15 54.7 0.3 3.2 1 1 2 3 3 3 3 Myb-like DNA-binding domain SLIDE PF09111.10 OQS02967.1 - 0.00019 21.4 0.5 0.88 9.6 0.0 3.7 1 1 2 3 3 3 2 SLIDE Myb_DNA-bind_7 PF15963.5 OQS02967.1 - 0.0017 18.2 1.0 1.6 8.6 0.2 2.6 3 0 0 3 3 3 2 Myb DNA-binding like Rap1_C PF11626.8 OQS02967.1 - 0.0089 16.1 0.0 4.2 7.5 0.0 3.2 1 1 0 2 2 2 1 TRF2-interacting telomeric protein/Rap1 - C terminal domain DUF722 PF05263.11 OQS02967.1 - 0.019 15.2 0.8 1.1 9.5 0.1 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF722) Myb_DNA-bind_2 PF08914.11 OQS02967.1 - 0.043 14.0 1.3 20 5.5 0.1 3.4 2 1 1 3 3 3 0 Rap1 Myb domain SANT_DAMP1_like PF16282.5 OQS02967.1 - 0.08 13.2 1.0 39 4.5 0.0 3.1 1 1 2 3 3 3 0 SANT/Myb-like domain of DAMP1 Myb_DNA-bind_4 PF13837.6 OQS02967.1 - 6.1 7.3 10.5 4.8 7.6 0.5 3.5 2 2 1 3 3 3 0 Myb/SANT-like DNA-binding domain LBR_tudor PF09465.10 OQS02968.1 - 0.021 14.6 0.0 0.15 11.9 0.0 2.2 2 0 0 2 2 2 0 Lamin-B receptor of TUDOR domain Hist_deacetyl PF00850.19 OQS02969.1 - 2.2e-82 277.0 0.3 2.7e-82 276.7 0.3 1.1 1 0 0 1 1 1 1 Histone deacetylase domain NAD_binding_1 PF00175.21 OQS02970.1 - 3.3e-12 47.0 0.0 6.2e-12 46.1 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 OQS02970.1 - 3.7e-09 36.8 0.0 7.4e-09 35.9 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain Globin PF00042.22 OQS02970.1 - 5.1e-09 36.7 0.0 1.2e-08 35.5 0.0 1.6 2 0 0 2 2 2 1 Globin NAD_binding_6 PF08030.12 OQS02970.1 - 4.4e-06 26.9 0.0 3.3e-05 24.1 0.0 2.0 1 1 0 2 2 2 1 Ferric reductase NAD binding domain Protoglobin PF11563.8 OQS02970.1 - 0.15 12.0 0.0 1.5 8.7 0.0 2.4 2 1 0 2 2 2 0 Protoglobin Tfb5 PF06331.12 OQS02971.1 - 2.1e-22 78.9 0.0 2.5e-22 78.7 0.0 1.0 1 0 0 1 1 1 1 Transcription factor TFIIH complex subunit Tfb5 Pro-kuma_activ PF09286.11 OQS02973.1 - 2.2e-24 86.4 0.1 4.2e-24 85.5 0.1 1.4 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 OQS02973.1 - 3.6e-07 29.8 0.1 6.4e-07 28.9 0.1 1.4 1 0 0 1 1 1 1 Subtilase family Trp_oprn_chp PF09534.10 OQS02973.1 - 0.015 15.1 0.2 0.031 14.1 0.2 1.4 1 0 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Pkinase PF00069.25 OQS02974.1 - 7.5e-64 215.6 0.0 1.3e-63 214.9 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain cNMP_binding PF00027.29 OQS02974.1 - 7.2e-37 125.4 0.0 1.2e-17 63.7 0.0 3.2 4 0 0 4 4 4 2 Cyclic nucleotide-binding domain Pkinase_Tyr PF07714.17 OQS02974.1 - 2e-30 105.9 0.0 3.7e-30 105.1 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OQS02974.1 - 0.0075 15.6 0.0 0.017 14.5 0.0 1.5 1 0 0 1 1 1 1 Kinase-like IFT20 PF14931.6 OQS02974.1 - 0.082 13.1 0.5 0.19 11.9 0.5 1.5 1 0 0 1 1 1 0 Intraflagellar transport complex B, subunit 20 TPX2_importin PF12214.8 OQS02975.1 - 0.038 14.2 0.2 0.063 13.5 0.2 1.3 1 0 0 1 1 1 0 Cell cycle regulated microtubule associated protein ParcG PF10274.9 OQS02976.1 - 3.3e-72 242.5 0.0 5.3e-72 241.8 0.0 1.3 1 0 0 1 1 1 1 Parkin co-regulated protein Pkinase PF00069.25 OQS02976.1 - 3.1e-49 167.7 0.0 1.2e-43 149.4 0.0 2.2 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OQS02976.1 - 3.2e-32 111.8 0.0 2e-31 109.3 0.0 1.9 1 1 1 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 OQS02976.1 - 0.00036 20.0 0.3 0.0021 17.4 0.1 2.0 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 OQS02976.1 - 0.009 14.8 1.3 0.013 14.3 0.0 1.8 2 0 0 2 2 2 1 Fungal protein kinase FTA2 PF13095.6 OQS02976.1 - 0.01 15.5 0.0 2.5 7.7 0.0 2.4 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Haspin_kinase PF12330.8 OQS02976.1 - 2.9 6.7 6.1 0.2 10.6 0.2 2.0 2 1 0 2 2 2 0 Haspin like kinase domain RhoGAP PF00620.27 OQS02977.1 - 2.4e-13 50.2 0.0 9.8e-13 48.2 0.0 1.8 1 1 0 1 1 1 1 RhoGAP domain Acetyltransf_3 PF13302.7 OQS02978.1 - 1.3e-19 71.2 0.0 1.7e-19 70.9 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 OQS02978.1 - 1.9e-06 28.1 0.1 0.00015 22.0 0.0 2.4 1 1 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 OQS02978.1 - 0.0047 17.1 0.0 0.0094 16.2 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family bZIP_2 PF07716.15 OQS02979.1 - 0.00013 22.0 14.4 0.00016 21.7 5.7 2.7 2 1 0 2 2 2 1 Basic region leucine zipper bZIP_1 PF00170.21 OQS02979.1 - 0.0011 19.0 8.1 0.0032 17.5 2.8 2.5 2 0 0 2 2 2 1 bZIP transcription factor ABC_tran_CTD PF16326.5 OQS02979.1 - 0.058 13.7 1.3 0.17 12.2 1.2 2.0 1 1 0 1 1 1 0 ABC transporter C-terminal domain DUF4618 PF15397.6 OQS02979.1 - 0.2 11.0 6.7 2.6 7.4 3.3 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4618) PikAIV_N PF18605.1 OQS02979.1 - 0.3 10.7 3.6 0.71 9.5 3.6 1.7 1 0 0 1 1 1 0 Narbonolide/10-deoxymethynolide synthase PikA4 N-terminal domain Mif2_N PF15624.6 OQS02979.1 - 0.44 11.2 5.2 0.38 11.5 3.6 1.7 2 0 0 2 2 2 0 Kinetochore CENP-C fungal homologue, Mif2, N-terminal HALZ PF02183.18 OQS02979.1 - 1.3 9.3 5.0 17 5.7 0.4 2.6 2 0 0 2 2 2 0 Homeobox associated leucine zipper MutS_III PF05192.18 OQS02979.1 - 2.6 8.2 5.6 7.1 6.8 5.3 1.7 1 1 1 2 2 2 0 MutS domain III DUF1515 PF07439.11 OQS02979.1 - 3.3 7.8 6.6 20 5.3 4.7 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1515) bZIP_Maf PF03131.17 OQS02979.1 - 7.2 7.2 14.3 0.69 10.5 6.9 2.7 1 1 2 3 3 3 0 bZIP Maf transcription factor DivIC PF04977.15 OQS02979.1 - 8.1 6.3 9.8 4 7.3 1.9 2.7 1 1 1 2 2 2 0 Septum formation initiator FANC_SAP PF18081.1 OQS02980.1 - 0.044 14.0 0.0 0.096 12.9 0.0 1.6 1 0 0 1 1 1 0 Fanconi anemia-associated nuclease SAP domain PI3_PI4_kinase PF00454.27 OQS02981.1 - 5.4e-33 114.9 0.0 8.7e-33 114.2 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase COPIIcoated_ERV PF07970.12 OQS02981.1 - 8.1e-26 91.2 0.1 1.5e-25 90.4 0.1 1.4 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 OQS02981.1 - 2e-21 76.1 0.1 4.9e-21 74.9 0.1 1.7 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Thioredoxin PF00085.20 OQS02981.1 - 4.8e-16 58.6 0.0 1.1e-15 57.5 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin ubiquitin PF00240.23 OQS02981.1 - 1e-08 34.8 0.1 2e-08 33.9 0.1 1.5 1 0 0 1 1 1 1 Ubiquitin family Thioredoxin_2 PF13098.6 OQS02981.1 - 0.042 14.3 0.0 0.13 12.7 0.0 1.8 1 0 0 1 1 1 0 Thioredoxin-like domain Phage_pRha PF09669.10 OQS02981.1 - 0.13 12.8 0.0 25 5.5 0.0 3.5 3 0 0 3 3 3 0 Phage regulatory protein Rha (Phage_pRha) Metallophos PF00149.28 OQS02982.1 - 2.3e-60 204.6 3.2 1.5e-30 107.3 0.2 2.9 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase EF-hand_1 PF00036.32 OQS02982.1 - 1.5e-23 80.5 6.7 2.4e-06 26.7 0.1 6.6 6 0 0 6 6 6 5 EF hand EF-hand_6 PF13405.6 OQS02982.1 - 2.5e-21 73.7 4.6 4.9e-05 22.9 0.1 7.0 6 0 0 6 6 6 5 EF-hand domain PPP5 PF08321.12 OQS02982.1 - 5.8e-19 68.2 0.1 3.8e-09 36.7 0.1 2.9 2 0 0 2 2 2 2 PPP5 TPR repeat region EF-hand_7 PF13499.6 OQS02982.1 - 1.3e-18 67.2 4.7 1.2e-07 32.0 0.3 5.0 3 1 1 4 4 4 3 EF-hand domain pair EF-hand_8 PF13833.6 OQS02982.1 - 7.7e-13 48.1 5.0 0.00035 20.4 0.0 5.1 4 0 0 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.6 OQS02982.1 - 3.6e-11 42.0 13.3 5.5e-05 22.5 0.2 5.3 6 0 0 6 6 6 2 EF hand EF-hand_9 PF14658.6 OQS02982.1 - 0.00014 22.1 0.0 0.32 11.3 0.0 4.1 3 0 0 3 3 3 1 EF-hand domain SPARC_Ca_bdg PF10591.9 OQS02982.1 - 0.00061 20.1 1.0 4.7 7.6 0.0 3.9 3 1 0 3 3 3 2 Secreted protein acidic and rich in cysteine Ca binding region Peptidase_M9 PF01752.17 OQS02982.1 - 0.015 14.6 0.3 0.47 9.7 0.0 2.6 3 0 0 3 3 3 0 Collagenase RPN13_C PF16550.5 OQS02982.1 - 0.15 12.2 4.3 0.67 10.1 0.2 3.7 4 0 0 4 4 4 0 UCH-binding domain EF-hand_4 PF12763.7 OQS02982.1 - 0.67 9.9 2.9 8.5 6.4 0.0 3.7 4 1 1 5 5 5 0 Cytoskeletal-regulatory complex EF hand Sel1 PF08238.12 OQS02983.1 - 1.3e-40 136.9 41.0 8.7e-08 32.6 0.2 10.0 10 0 0 10 10 10 9 Sel1 repeat LIN52 PF10044.9 OQS02984.1 - 0.0002 22.0 0.0 0.00036 21.2 0.0 1.4 1 0 0 1 1 1 1 Retinal tissue protein zf-RING_2 PF13639.6 OQS02985.1 - 9.3e-09 35.5 9.2 9.3e-09 35.5 9.2 4.4 3 0 0 3 3 3 1 Ring finger domain zf-rbx1 PF12678.7 OQS02985.1 - 7.6e-07 29.3 6.3 7.6e-07 29.3 6.3 2.9 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-RING_11 PF17123.5 OQS02985.1 - 3.1e-06 26.8 1.4 1.7e-05 24.5 1.4 2.4 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 OQS02985.1 - 0.00017 21.4 8.8 0.00017 21.4 8.8 3.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) HMA PF00403.26 OQS02985.1 - 0.00043 20.7 0.1 0.004 17.6 0.0 2.5 2 0 0 2 2 2 1 Heavy-metal-associated domain zf-C3HC4 PF00097.25 OQS02985.1 - 0.0012 18.7 10.5 0.0012 18.7 10.5 2.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 OQS02985.1 - 0.0033 17.4 4.6 0.0033 17.4 4.6 3.7 3 2 0 4 4 4 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.6 OQS02985.1 - 5.9 6.9 23.2 0.021 14.7 9.5 4.0 2 1 1 3 3 3 0 zinc-RING finger domain Beta-Casp PF10996.8 OQS02987.1 - 0.0066 16.7 0.0 0.02 15.2 0.0 1.8 1 0 0 1 1 1 1 Beta-Casp domain BBS2_N PF14781.6 OQS02987.1 - 0.017 15.0 0.2 0.034 14.1 0.2 1.5 1 0 0 1 1 1 0 Ciliary BBSome complex subunit 2, N-terminal Trypsin_2 PF13365.6 OQS02988.1 - 3.7e-31 109.0 0.3 4.4e-14 53.6 0.1 2.4 2 0 0 2 2 2 2 Trypsin-like peptidase domain Trypsin PF00089.26 OQS02988.1 - 3.7e-08 33.5 7.4 5.9e-05 23.0 0.5 3.1 2 1 0 2 2 2 2 Trypsin Peptidase_S7 PF00949.21 OQS02988.1 - 0.079 12.8 1.2 12 5.7 0.3 2.6 2 0 0 2 2 2 0 Peptidase S7, Flavivirus NS3 serine protease Peptidase_S46 PF10459.9 OQS02988.1 - 1.1 7.8 8.2 8.9 4.8 0.1 3.8 4 0 0 4 4 4 0 Peptidase S46 Pkinase PF00069.25 OQS02990.1 - 1.6e-64 217.9 0.0 2.2e-64 217.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQS02990.1 - 1.9e-25 89.6 0.0 8.7e-25 87.5 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 OQS02990.1 - 0.0043 16.0 0.0 0.008 15.2 0.0 1.4 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 OQS02990.1 - 0.013 14.8 0.0 0.026 13.8 0.0 1.5 1 0 0 1 1 1 0 Kinase-like Kdo PF06293.14 OQS02990.1 - 0.19 11.1 0.2 0.64 9.3 0.1 1.8 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_Tyr PF07714.17 OQS02991.1 - 3.2e-57 193.8 0.0 6.1e-57 192.9 0.0 1.4 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.25 OQS02991.1 - 7.4e-40 137.0 0.0 1.1e-39 136.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain GYF PF02213.16 OQS02991.1 - 0.19 11.5 0.2 0.59 9.8 0.0 1.9 2 0 0 2 2 2 0 GYF domain Kdo PF06293.14 OQS02991.1 - 0.22 10.9 0.0 0.37 10.1 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Ribosomal_S7e PF01251.18 OQS02994.1 - 2.3e-76 255.6 3.9 6.5e-75 250.9 3.9 2.0 1 1 0 1 1 1 1 Ribosomal protein S7e ORC6 PF05460.13 OQS02995.1 - 2.3e-06 27.1 4.7 1.6e-05 24.3 0.0 2.8 2 1 0 3 3 3 2 Origin recognition complex subunit 6 (ORC6) NifU_N PF01592.16 OQS02996.1 - 2e-54 183.2 0.2 2.3e-54 183.0 0.2 1.0 1 0 0 1 1 1 1 NifU-like N terminal domain GLTP PF08718.11 OQS02997.1 - 2e-24 86.5 0.0 3.3e-24 85.9 0.0 1.3 1 0 0 1 1 1 1 Glycolipid transfer protein (GLTP) FYVE PF01363.21 OQS02997.1 - 2.8e-10 40.2 9.9 5.3e-10 39.3 9.9 1.5 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.16 OQS02997.1 - 0.022 15.0 4.6 0.022 15.0 4.6 2.0 2 0 0 2 2 2 0 FYVE-type zinc finger Rad50_zn_hook PF04423.14 OQS02997.1 - 0.14 12.0 1.2 0.25 11.2 0.1 1.9 2 0 0 2 2 2 0 Rad50 zinc hook motif IBR PF01485.21 OQS02997.1 - 0.39 11.0 6.5 0.9 9.8 6.5 1.6 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain zf-B_box PF00643.24 OQS02997.1 - 0.97 9.6 8.7 2.9 8.1 8.7 1.8 1 0 0 1 1 1 0 B-box zinc finger Saf_2TM PF18303.1 OQS02998.1 - 0.061 12.9 2.4 0.19 11.3 0.1 2.3 1 1 1 2 2 2 0 SAVED-fused 2TM effector domain Adenosine_kin PF04008.14 OQS02998.1 - 0.07 12.9 0.1 0.094 12.5 0.1 1.3 1 0 0 1 1 1 0 Adenosine specific kinase DUF1616 PF07760.11 OQS02998.1 - 0.072 12.5 2.0 0.089 12.2 2.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1616) Rab5ip PF07019.12 OQS02998.1 - 0.073 13.7 0.6 0.073 13.7 0.6 2.0 1 1 1 2 2 2 0 Rab5-interacting protein (Rab5ip) TcpE PF12648.7 OQS02998.1 - 0.39 11.3 5.7 1.5 9.4 0.2 2.1 1 1 1 2 2 2 0 TcpE family MpPF26 PF07666.11 OQS02998.1 - 0.39 10.8 4.5 0.98 9.5 4.5 1.7 1 1 0 1 1 1 0 M penetrans paralogue family 26 DUF3488 PF11992.8 OQS02998.1 - 1.8 7.4 8.3 3.9 6.3 3.3 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF3488) DUF3754 PF12576.8 OQS02998.1 - 4.6 7.2 5.9 40 4.2 5.9 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF3754) DUF2070 PF09843.9 OQS02998.1 - 5.3 5.2 6.7 6.2 5.0 6.7 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) DUF4131 PF13567.6 OQS02998.1 - 6.1 6.5 10.8 2.4e+02 1.3 10.8 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4131) Alg14 PF08660.11 OQS02999.1 - 1.6e-64 217.0 0.0 2.4e-64 216.5 0.0 1.2 1 0 0 1 1 1 1 Oligosaccharide biosynthesis protein Alg14 like Ribosomal_S19e PF01090.19 OQS02999.1 - 5.2e-53 178.4 0.1 8e-53 177.8 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein S19e Tmemb_185A PF10269.9 OQS03000.1 - 1.4e-07 31.5 17.6 0.00033 20.4 0.1 3.1 1 1 2 3 3 3 3 Transmembrane Fragile-X-F protein Nop PF01798.18 OQS03001.1 - 5.8e-84 281.1 0.0 5.8e-84 281.1 0.0 2.1 3 0 0 3 3 3 1 snoRNA binding domain, fibrillarin NOP5NT PF08156.13 OQS03001.1 - 3.9e-19 68.8 2.3 3.9e-19 68.8 2.3 2.6 2 1 0 2 2 2 1 NOP5NT (NUC127) domain RNA_polI_A34 PF08208.11 OQS03001.1 - 2.4 8.2 40.4 4.3 7.4 40.4 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 RR_TM4-6 PF06459.12 OQS03001.1 - 3.2 7.5 21.8 5.3 6.8 21.8 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF1383 PF07134.11 OQS03002.1 - 0.03 13.4 0.8 0.048 12.8 0.2 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1383) Spo12 PF05032.12 OQS03002.1 - 6.7 6.7 5.2 6.8 6.7 0.1 3.1 3 0 0 3 3 3 0 Spo12 family Tmemb_185A PF10269.9 OQS03003.1 - 4.8e-21 75.6 132.3 4e-06 26.7 7.2 10.9 5 2 5 10 10 10 9 Transmembrane Fragile-X-F protein Podoplanin PF05808.11 OQS03003.1 - 2 8.5 4.0 3.5 7.7 0.2 2.8 2 0 0 2 2 2 0 Podoplanin bZIP_1 PF00170.21 OQS03004.1 - 7.8e-07 29.1 6.2 7.8e-07 29.1 6.2 2.2 2 1 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.15 OQS03004.1 - 0.0062 16.6 7.7 0.022 14.8 7.7 2.0 1 0 0 1 1 1 1 Basic region leucine zipper Sedlin_N PF04628.13 OQS03005.1 - 1.1e-37 129.1 0.2 1.3e-37 128.9 0.2 1.0 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Sybindin PF04099.12 OQS03005.1 - 3.4e-10 40.0 0.3 1.1e-09 38.4 0.1 1.7 1 1 0 2 2 2 1 Sybindin-like family DUF508 PF04370.12 OQS03005.1 - 0.0062 16.3 0.3 0.036 13.8 0.1 1.9 1 1 1 2 2 2 1 Domain of unknown function (DUF508) Tmemb_185A PF10269.9 OQS03006.1 - 1e-09 38.4 27.4 3.1e-06 27.1 10.9 4.0 3 1 1 4 4 4 3 Transmembrane Fragile-X-F protein PIG-L PF02585.17 OQS03009.1 - 2.5e-11 44.3 2.8 2.3e-10 41.2 0.0 3.1 2 1 0 2 2 2 1 GlcNAc-PI de-N-acetylase PH PF00169.29 OQS03009.1 - 5.1e-09 36.6 0.5 1.4e-08 35.2 0.5 1.7 1 0 0 1 1 1 1 PH domain FKBP_C PF00254.28 OQS03009.1 - 0.0037 17.5 0.0 0.012 15.9 0.0 1.8 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase DUF1043 PF06295.12 OQS03009.1 - 0.0075 16.3 3.8 0.0075 16.3 3.8 4.2 2 1 1 4 4 4 1 Protein of unknown function (DUF1043) TMEMspv1-c74-12 PF11044.8 OQS03009.1 - 0.13 12.2 0.5 6.4 6.8 0.0 3.2 3 0 0 3 3 3 0 Plectrovirus spv1-c74 ORF 12 transmembrane protein PH_9 PF15410.6 OQS03009.1 - 0.21 11.9 2.4 0.27 11.6 0.4 2.2 2 0 0 2 2 2 0 Pleckstrin homology domain DNA_pol_phi PF04931.13 OQS03010.1 - 2e-114 383.4 54.4 3.7e-110 369.3 44.6 4.1 2 1 0 2 2 2 2 DNA polymerase phi RRN3 PF05327.11 OQS03010.1 - 0.014 14.0 6.6 0.057 12.0 6.6 2.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 NDUF_C2 PF06374.11 OQS03011.1 - 0.076 13.2 0.0 0.088 13.0 0.0 1.1 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase subunit b14.5b (NDUFC2) Voltage_CLC PF00654.20 OQS03011.1 - 0.11 11.7 0.4 0.13 11.5 0.4 1.0 1 0 0 1 1 1 0 Voltage gated chloride channel S-AdoMet_synt_C PF02773.16 OQS03013.1 - 6e-59 198.0 0.2 1.9e-58 196.4 0.2 1.9 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M PF02772.16 OQS03013.1 - 1.1e-47 161.2 0.0 5e-47 159.1 0.0 2.3 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.20 OQS03013.1 - 1.2e-43 147.8 0.1 3.3e-43 146.4 0.1 1.8 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, N-terminal domain Pyridoxal_deC PF00282.19 OQS03014.1 - 9.9e-180 597.1 0.0 2.3e-91 306.3 0.0 2.1 2 0 0 2 2 2 2 Pyridoxal-dependent decarboxylase conserved domain Beta_elim_lyase PF01212.21 OQS03014.1 - 3.3e-11 43.0 0.3 1.6e-05 24.4 0.0 2.2 2 0 0 2 2 2 2 Beta-eliminating lyase Aminotran_1_2 PF00155.21 OQS03014.1 - 1.4e-07 31.0 0.7 1.3 8.1 0.0 4.2 4 0 0 4 4 4 4 Aminotransferase class I and II bPH_5 PF10882.8 OQS03014.1 - 0.011 15.8 0.0 2.5 8.2 0.0 2.4 2 0 0 2 2 2 0 Bacterial PH domain Fijivirus_P9-2 PF06837.11 OQS03014.1 - 0.013 14.9 0.0 0.04 13.4 0.0 1.8 1 0 0 1 1 1 0 Fijivirus P9-2 protein CNP1 PF08750.11 OQS03014.1 - 0.057 13.4 0.3 1.4 8.9 0.0 2.5 2 0 0 2 2 2 0 CNP1-like family Zip PF02535.22 OQS03015.1 - 6.1e-34 117.7 6.8 1e-33 117.0 6.8 1.3 1 0 0 1 1 1 1 ZIP Zinc transporter Methyltransf_32 PF13679.6 OQS03015.1 - 3.9e-12 46.4 2.2 1.2e-10 41.6 2.2 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OQS03015.1 - 1.3e-06 28.3 0.1 2.1e-06 27.6 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain TRM13 PF05206.14 OQS03015.1 - 1.4e-06 28.0 0.9 2.7e-05 23.9 1.0 2.4 1 1 0 1 1 1 1 Methyltransferase TRM13 Methyltransf_4 PF02390.17 OQS03015.1 - 6.4e-06 25.8 0.0 1.4e-05 24.6 0.0 1.6 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_25 PF13649.6 OQS03015.1 - 1.2e-05 25.9 0.1 2.4e-05 25.0 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase domain GidB PF02527.15 OQS03015.1 - 0.0002 20.8 0.0 0.0004 19.7 0.0 1.4 1 0 0 1 1 1 1 rRNA small subunit methyltransferase G MTS PF05175.14 OQS03015.1 - 0.0073 15.9 0.0 0.013 15.0 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase small domain tRNA_U5-meth_tr PF05958.11 OQS03015.1 - 0.071 12.1 0.0 0.11 11.4 0.0 1.3 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase Met_10 PF02475.16 OQS03015.1 - 0.095 12.4 0.0 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 Met-10+ like-protein HupE_UreJ PF04955.12 OQS03015.1 - 0.53 9.7 5.9 1 8.8 5.9 1.4 1 0 0 1 1 1 0 HupE / UreJ protein Chitin_bind_1 PF00187.19 OQS03016.1 - 1.4e-16 60.7 67.2 2e-06 28.1 13.7 4.4 5 0 0 5 5 5 3 Chitin recognition protein Ank_2 PF12796.7 OQS03017.1 - 1e-08 35.6 2.9 4.2e-05 24.0 0.3 1.7 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQS03017.1 - 4e-06 27.3 0.6 0.016 15.8 0.1 2.8 2 1 0 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 OQS03017.1 - 4.7e-05 23.6 0.6 0.008 16.5 0.0 2.9 1 1 2 3 3 3 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQS03017.1 - 0.0017 18.7 0.0 0.44 11.3 0.0 3.3 3 0 0 3 3 3 1 Ankyrin repeat Ank_4 PF13637.6 OQS03018.1 - 4.3e-28 97.3 4.1 7.7e-06 26.4 0.1 7.0 4 2 4 8 8 8 7 Ankyrin repeats (many copies) Ank_2 PF12796.7 OQS03018.1 - 1.3e-25 89.8 12.7 0.00018 22.0 0.2 5.7 1 1 4 6 6 6 6 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OQS03018.1 - 4e-25 87.5 6.5 0.0085 16.4 0.0 9.7 3 2 8 11 11 11 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQS03018.1 - 1.2e-16 59.1 0.6 0.16 12.6 0.0 9.7 11 0 0 11 11 11 4 Ankyrin repeat Ank PF00023.30 OQS03018.1 - 1.9e-06 28.1 1.9 2.6 8.6 0.0 6.5 4 3 1 5 5 5 1 Ankyrin repeat DUF5049 PF16468.5 OQS03018.1 - 5.8e-05 22.9 5.6 15 5.6 0.0 7.5 8 2 2 10 10 10 1 Domain of unknown function (DUF5049) Helicase_PWI PF18149.1 OQS03018.1 - 0.025 14.8 0.2 2.7 8.2 0.0 3.4 4 0 0 4 4 4 0 N-terminal helicase PWI domain HA PF03457.14 OQS03018.1 - 0.044 14.1 4.9 1.3 9.4 0.0 4.1 5 0 0 5 5 5 0 Helicase associated domain FAM195 PF14799.6 OQS03018.1 - 3.8 7.9 8.2 98 3.4 2.2 4.6 2 1 1 3 3 3 0 FAM195 family Peptidase_S10 PF00450.22 OQS03019.1 - 1.3e-65 222.5 2.9 1.6e-65 222.2 2.9 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase RVT_1 PF00078.27 OQS03020.1 - 1.1e-10 41.4 0.0 6.5e-05 22.5 0.0 2.3 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos PF03372.23 OQS03020.1 - 0.12 11.8 0.7 0.33 10.4 0.7 1.7 1 1 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family Prefoldin PF02996.17 OQS03021.1 - 9.8e-28 96.5 0.5 1.2e-27 96.2 0.5 1.1 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin_2 PF01920.20 OQS03021.1 - 0.0029 17.5 1.2 0.15 12.0 0.1 2.3 1 1 1 2 2 2 2 Prefoldin subunit DUF4795 PF16043.5 OQS03021.1 - 0.0093 15.6 0.5 0.012 15.2 0.5 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4795) Cauli_AT PF03233.13 OQS03021.1 - 0.17 11.8 1.4 1 9.3 0.2 2.0 2 0 0 2 2 2 0 Aphid transmission protein DUF2180 PF09947.9 OQS03021.1 - 0.22 11.5 0.0 0.43 10.6 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2180) Nuc_recep-AF1 PF11825.8 OQS03022.1 - 0.073 13.1 0.1 0.13 12.3 0.1 1.5 1 1 0 1 1 1 0 Nuclear/hormone receptor activator site AF-1 ABC2_membrane PF01061.24 OQS03023.1 - 7e-21 74.6 19.8 9.4e-21 74.2 19.8 1.2 1 0 0 1 1 1 1 ABC-2 type transporter ABC2_membrane_3 PF12698.7 OQS03023.1 - 0.014 14.5 17.1 0.017 14.3 17.1 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein Peptidase_U4 PF03419.13 OQS03023.1 - 2.8 7.1 7.9 4.2 6.6 7.9 1.2 1 0 0 1 1 1 0 Sporulation factor SpoIIGA Hydrolase_6 PF13344.6 OQS03024.1 - 2.7e-25 88.4 0.0 4.5e-25 87.7 0.0 1.4 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 OQS03024.1 - 1.4e-19 69.9 0.0 7e-19 67.7 0.0 2.0 2 0 0 2 2 2 1 HAD-hyrolase-like HAD_2 PF13419.6 OQS03024.1 - 0.003 17.7 0.0 0.082 13.0 0.0 2.6 2 1 1 3 3 3 1 Haloacid dehalogenase-like hydrolase DUF1611 PF07755.11 OQS03024.1 - 0.077 12.3 0.0 0.13 11.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1611_C) P-loop domain Hydrolase PF00702.26 OQS03024.1 - 0.083 13.2 0.0 23 5.2 0.0 2.6 2 1 1 3 3 3 0 haloacid dehalogenase-like hydrolase Pkinase PF00069.25 OQS03025.1 - 2.1e-66 224.0 0.0 3.2e-66 223.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQS03025.1 - 3.6e-28 98.6 0.0 6.6e-28 97.7 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase PH PF00169.29 OQS03025.1 - 1.5e-07 31.9 0.0 3.2e-07 30.8 0.0 1.6 1 0 0 1 1 1 1 PH domain Haspin_kinase PF12330.8 OQS03025.1 - 0.007 15.3 0.1 0.015 14.3 0.1 1.4 1 1 0 1 1 1 1 Haspin like kinase domain RIO1 PF01163.22 OQS03025.1 - 0.023 14.3 0.2 1 8.9 0.2 2.7 2 0 0 2 2 2 0 RIO1 family Kdo PF06293.14 OQS03025.1 - 0.023 14.1 0.1 0.04 13.3 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 OQS03025.1 - 0.043 13.1 0.0 0.078 12.3 0.0 1.3 1 0 0 1 1 1 0 Kinase-like SH3BP5 PF05276.14 OQS03026.1 - 0.0055 16.5 19.2 0.0055 16.5 19.2 2.4 2 1 0 2 2 2 1 SH3 domain-binding protein 5 (SH3BP5) AAA_23 PF13476.6 OQS03026.1 - 0.055 14.0 40.9 0.044 14.3 14.0 2.6 2 1 0 2 2 2 0 AAA domain DUF4398 PF14346.6 OQS03026.1 - 1.2 9.8 60.5 0.081 13.5 15.8 4.7 2 2 1 3 3 3 0 Domain of unknown function (DUF4398) TCR PF03638.15 OQS03027.1 - 3e-23 81.8 58.5 6.2e-13 48.8 24.5 2.4 2 0 0 2 2 2 2 Tesmin/TSO1-like CXC domain, cysteine-rich domain MSL2-CXC PF16682.5 OQS03027.1 - 2.9 8.1 49.7 0.3 11.2 17.4 2.8 2 1 0 2 2 2 0 CXC domain of E3 ubiquitin-protein ligase MSL2 TPR_14 PF13428.6 OQS03029.1 - 7e-05 23.3 45.6 0.22 12.5 1.5 13.1 11 3 2 13 13 13 3 Tetratricopeptide repeat HEAT PF02985.22 OQS03029.1 - 0.17 12.2 3.6 24 5.5 0.0 5.0 6 0 0 6 6 6 0 HEAT repeat Consortin_C PF15281.6 OQS03031.1 - 0.13 12.2 0.2 0.26 11.3 0.2 1.5 1 0 0 1 1 1 0 Consortin C-terminus Viral_alk_exo PF01771.17 OQS03031.1 - 0.23 10.3 0.1 0.36 9.6 0.1 1.2 1 0 0 1 1 1 0 Viral alkaline exonuclease ATPase_gene1 PF09527.10 OQS03031.1 - 2.1 8.6 7.9 4.2 7.6 7.9 1.6 1 0 0 1 1 1 0 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter Ricin_B_lectin PF00652.22 OQS03032.1 - 1.8e-07 31.5 6.4 0.00032 21.0 0.1 2.1 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain DUF2752 PF10825.8 OQS03032.1 - 0.11 12.6 0.8 0.21 11.7 0.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2752) Ank_4 PF13637.6 OQS03033.1 - 5.4e-06 26.8 0.0 2.7e-05 24.6 0.0 2.2 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 OQS03033.1 - 7.1e-06 26.5 0.0 5.7e-05 23.6 0.0 2.2 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank PF00023.30 OQS03033.1 - 8.7e-05 22.8 0.4 0.034 14.6 0.0 3.6 4 0 0 4 4 4 1 Ankyrin repeat Cwf_Cwc_15 PF04889.12 OQS03033.1 - 0.079 12.7 6.4 0.12 12.1 6.4 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DNA_pol_phi PF04931.13 OQS03033.1 - 2.5 6.1 7.4 3.4 5.6 7.4 1.1 1 0 0 1 1 1 0 DNA polymerase phi TFIIE-A_C PF11521.8 OQS03033.1 - 4.8 7.6 10.6 10 6.5 10.6 1.5 1 0 0 1 1 1 0 C-terminal general transcription factor TFIIE alpha G-patch PF01585.23 OQS03034.1 - 2.7e-18 65.6 0.3 2.7e-18 65.6 0.3 1.9 2 0 0 2 2 2 1 G-patch domain G-patch_2 PF12656.7 OQS03034.1 - 7.4e-07 29.2 0.3 7.4e-07 29.2 0.3 2.1 2 0 0 2 2 2 1 G-patch domain Ephrin_rec_like PF07699.13 OQS03036.1 - 1.9e-06 27.5 24.6 0.012 15.3 3.7 4.3 1 1 3 4 4 4 3 Putative ephrin-receptor like NCD3G PF07562.14 OQS03036.1 - 0.00018 21.4 12.0 0.024 14.6 5.6 3.6 2 1 1 3 3 3 2 Nine Cysteines Domain of family 3 GPCR PikAIV_N PF18605.1 OQS03036.1 - 0.0011 18.4 7.7 0.058 13.0 3.4 2.4 2 0 0 2 2 2 2 Narbonolide/10-deoxymethynolide synthase PikA4 N-terminal domain ZapB PF06005.12 OQS03036.1 - 0.0016 18.9 9.8 0.077 13.4 0.6 2.3 1 1 1 2 2 2 2 Cell division protein ZapB Furin-like PF00757.20 OQS03036.1 - 0.0021 17.9 4.3 0.045 13.6 0.5 2.2 1 1 1 2 2 2 1 Furin-like cysteine rich region KLRAQ PF10205.9 OQS03036.1 - 0.019 15.2 1.9 0.034 14.4 1.9 1.3 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein NRBF2 PF08961.10 OQS03036.1 - 0.023 14.3 4.4 0.041 13.5 3.0 1.9 1 1 1 2 2 2 0 Nuclear receptor-binding factor 2, autophagy regulator bZIP_1 PF00170.21 OQS03036.1 - 0.1 12.7 5.1 1.7 8.8 0.4 2.3 1 1 1 2 2 2 0 bZIP transcription factor bZIP_2 PF07716.15 OQS03036.1 - 0.13 12.4 8.5 1.4 9.0 0.3 2.3 1 1 1 2 2 2 0 Basic region leucine zipper DivIC PF04977.15 OQS03036.1 - 0.14 11.9 9.6 0.2 11.4 1.7 2.5 1 1 1 2 2 2 0 Septum formation initiator MerR PF00376.23 OQS03036.1 - 0.16 11.8 1.6 21 5.0 0.0 2.9 3 0 0 3 3 3 0 MerR family regulatory protein Geminin PF07412.12 OQS03036.1 - 0.23 11.2 2.5 0.46 10.2 2.5 1.4 1 0 0 1 1 1 0 Geminin JIP_LZII PF16471.5 OQS03036.1 - 0.25 11.5 4.7 0.44 10.8 4.7 1.3 1 0 0 1 1 1 0 JNK-interacting protein leucine zipper II PRKG1_interact PF15898.5 OQS03036.1 - 0.34 11.8 5.2 0.78 10.7 1.6 2.3 1 1 1 2 2 2 0 cGMP-dependent protein kinase interacting domain CtIP_N PF10482.9 OQS03036.1 - 0.41 10.7 4.8 2.7 8.1 1.3 2.2 1 1 1 2 2 2 0 Tumour-suppressor protein CtIP N-terminal domain Shugoshin_N PF07558.11 OQS03036.1 - 1.3 8.9 7.6 10 6.1 1.4 2.7 2 1 1 3 3 3 0 Shugoshin N-terminal coiled-coil region GIT_CC PF16559.5 OQS03036.1 - 2.1 8.3 5.5 7.8 6.5 5.5 1.9 1 1 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor TSC22 PF01166.18 OQS03036.1 - 2.8 8.3 5.4 26 5.2 0.3 2.3 1 1 1 2 2 2 0 TSC-22/dip/bun family YabA PF06156.13 OQS03036.1 - 3.1 8.5 4.6 12 6.6 4.6 1.9 1 1 0 1 1 1 0 Initiation control protein YabA HALZ PF02183.18 OQS03036.1 - 4.1 7.7 8.0 5.9 7.2 1.4 2.3 2 0 0 2 2 2 0 Homeobox associated leucine zipper DUF3677 PF12432.8 OQS03037.1 - 6.2e-06 26.4 0.2 2.5e-05 24.5 0.2 2.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3677) Sec62 PF03839.16 OQS03037.1 - 5 6.6 6.9 12 5.3 6.9 1.6 1 0 0 1 1 1 0 Translocation protein Sec62 MMS19_N PF14500.6 OQS03037.1 - 5.8 6.4 8.1 14 5.1 0.2 4.3 5 1 1 6 6 6 0 Dos2-interacting transcription regulator of RNA-Pol-II PA PF02225.22 OQS03038.1 - 6.3e-08 32.5 0.0 1.6e-07 31.2 0.0 1.7 1 0 0 1 1 1 1 PA domain DUF4296 PF14129.6 OQS03038.1 - 0.022 15.4 0.0 0.037 14.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4296) EF-1_beta_acid PF10587.9 OQS03039.1 - 0.013 15.9 3.8 0.013 15.9 3.8 3.9 4 1 0 4 4 4 0 Eukaryotic elongation factor 1 beta central acidic region BLOC1S3 PF15753.5 OQS03039.1 - 0.66 10.1 8.3 0.061 13.5 3.3 1.8 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex 1 subunit 3 Ricin_B_lectin PF00652.22 OQS03041.1 - 1.2e-15 57.9 2.9 1.5e-09 38.1 1.2 2.1 2 0 0 2 2 2 2 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.6 OQS03041.1 - 0.00011 22.8 3.6 0.0021 18.8 0.5 2.8 1 1 2 3 3 3 1 Ricin-type beta-trefoil lectin domain-like CDtoxinA PF03498.14 OQS03041.1 - 0.033 13.8 2.6 0.12 12.0 0.3 2.3 2 1 0 2 2 2 0 Cytolethal distending toxin A/C domain Ras PF00071.22 OQS03042.1 - 3.1e-21 75.6 0.0 5.5e-21 74.8 0.0 1.5 1 1 0 1 1 1 1 Ras family Roc PF08477.13 OQS03042.1 - 1.5e-18 67.1 0.0 4.1e-18 65.7 0.0 1.8 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase 4HBT_2 PF13279.6 OQS03042.1 - 5.1e-16 59.3 0.2 1.4e-15 57.9 0.1 1.8 2 0 0 2 2 2 1 Thioesterase-like superfamily Arf PF00025.21 OQS03042.1 - 0.00045 19.7 0.0 0.00093 18.7 0.0 1.5 1 0 0 1 1 1 1 ADP-ribosylation factor family 4HBT PF03061.22 OQS03042.1 - 0.018 15.4 0.0 0.035 14.5 0.0 1.5 1 0 0 1 1 1 0 Thioesterase superfamily GTP_EFTU PF00009.27 OQS03042.1 - 0.1 12.1 0.0 0.19 11.3 0.0 1.4 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain DZR PF12773.7 OQS03043.1 - 1.9e-22 79.0 41.8 2.1e-11 43.7 5.4 4.5 3 1 1 4 4 4 4 Double zinc ribbon zinc_ribbon_2 PF13240.6 OQS03043.1 - 4.5e-14 51.6 72.8 0.00024 20.7 3.3 5.8 5 1 0 5 5 5 5 zinc-ribbon domain zinc_ribbon_15 PF17032.5 OQS03043.1 - 1.1e-12 48.5 32.3 0.0012 19.6 1.0 5.6 5 0 0 5 5 5 4 zinc-ribbon family zf-ribbon_3 PF13248.6 OQS03043.1 - 1.2e-07 30.9 65.0 9.6e-05 21.7 2.3 5.5 5 0 0 5 5 5 5 zinc-ribbon domain zf-C3HC4_3 PF13920.6 OQS03043.1 - 0.66 9.9 36.4 0.64 9.9 0.8 5.2 5 0 0 5 5 5 0 Zinc finger, C3HC4 type (RING finger) SPT2 PF08243.11 OQS03044.1 - 5.9e-16 59.0 19.4 5.9e-16 59.0 19.4 2.4 2 0 0 2 2 2 1 SPT2 chromatin protein SAM_1 PF00536.30 OQS03044.1 - 5.8e-11 42.7 0.0 1e-10 41.9 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 OQS03044.1 - 2.3e-07 30.8 0.0 4.4e-07 29.9 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Med26 PF08711.11 OQS03044.1 - 2.7e-07 30.5 0.5 7e-07 29.2 0.0 2.0 2 0 0 2 2 2 1 TFIIS helical bundle-like domain IQ PF00612.27 OQS03045.1 - 6.9e-27 90.7 131.5 0.0047 16.6 1.8 20.1 18 1 1 19 19 19 16 IQ calmodulin-binding motif WW PF00397.26 OQS03045.1 - 3.1e-13 49.5 23.7 7.5e-09 35.5 2.9 3.7 3 0 0 3 3 3 2 WW domain GIY-YIG PF01541.24 OQS03045.1 - 0.0069 16.6 0.6 0.049 13.9 0.1 2.8 1 1 1 2 2 2 1 GIY-YIG catalytic domain ArfGap PF01412.18 OQS03045.1 - 0.2 11.7 0.1 0.2 11.7 0.1 3.9 2 1 0 3 3 3 0 Putative GTPase activating protein for Arf zf-B_box PF00643.24 OQS03045.1 - 0.42 10.8 15.2 0.24 11.6 9.4 2.9 2 0 0 2 2 2 0 B-box zinc finger Lactococcin PF04369.13 OQS03045.1 - 4.4 7.5 4.6 9.7 6.4 0.4 2.7 2 0 0 2 2 2 0 Lactococcin-like family Pkinase PF00069.25 OQS03046.1 - 1.7e-67 227.6 0.0 2.3e-67 227.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQS03046.1 - 5e-38 130.9 0.0 7.3e-38 130.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase C2 PF00168.30 OQS03046.1 - 7.7e-14 51.8 0.4 5.3e-11 42.7 0.1 2.4 2 0 0 2 2 2 2 C2 domain FYVE PF01363.21 OQS03046.1 - 1.4e-05 25.2 16.5 3e-05 24.1 16.5 1.5 1 0 0 1 1 1 1 FYVE zinc finger Haspin_kinase PF12330.8 OQS03046.1 - 0.02 13.8 0.0 0.032 13.2 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain Kdo PF06293.14 OQS03046.1 - 0.036 13.4 0.0 0.073 12.4 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 OQS03046.1 - 0.082 12.2 0.0 0.16 11.3 0.0 1.4 1 0 0 1 1 1 0 Kinase-like FYVE_2 PF02318.16 OQS03046.1 - 0.092 13.0 8.7 0.22 11.8 8.7 1.5 1 0 0 1 1 1 0 FYVE-type zinc finger FA_hydroxylase PF04116.13 OQS03047.1 - 1e-21 77.7 21.4 1e-21 77.7 21.4 2.1 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily Pkinase_Tyr PF07714.17 OQS03048.1 - 2.3e-25 89.4 0.0 4.1e-25 88.5 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OQS03048.1 - 8.5e-21 74.5 0.0 1.3e-20 73.9 0.0 1.2 1 1 0 1 1 1 1 Protein kinase domain Arv1 PF04161.13 OQS03049.1 - 6.6 6.8 9.2 11 6.1 9.2 1.3 1 0 0 1 1 1 0 Arv1-like family Gln-synt_C PF00120.24 OQS03050.1 - 7.6e-19 67.9 0.0 5.9e-17 61.7 0.0 2.2 1 1 0 1 1 1 1 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.19 OQS03050.1 - 2.2e-13 49.7 0.0 3.8e-13 49.0 0.0 1.4 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain PhzC-PhzF PF02567.16 OQS03051.1 - 1.3e-49 169.2 0.1 1.7e-49 168.8 0.1 1.0 1 0 0 1 1 1 1 Phenazine biosynthesis-like protein ABC_membrane PF00664.23 OQS03052.1 - 1.4e-50 172.5 35.4 2.1e-25 89.9 14.6 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 OQS03052.1 - 6.4e-25 88.3 0.0 1.5e-24 87.1 0.0 1.6 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 OQS03052.1 - 9.5e-07 28.5 0.6 5.2e-05 22.8 0.6 2.2 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 OQS03052.1 - 0.0061 16.4 0.2 0.34 10.7 0.0 2.3 1 1 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 OQS03052.1 - 0.034 14.4 0.0 0.12 12.7 0.0 1.9 1 1 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 OQS03052.1 - 0.05 13.5 0.0 0.13 12.1 0.0 1.7 1 0 0 1 1 1 0 RsgA GTPase AAA_29 PF13555.6 OQS03052.1 - 0.078 12.7 0.0 0.27 11.0 0.0 1.9 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.6 OQS03052.1 - 0.088 13.3 0.0 0.2 12.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 OQS03052.1 - 0.099 12.2 0.0 0.21 11.1 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_15 PF13175.6 OQS03052.1 - 0.13 11.9 0.0 0.21 11.3 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain DUF815 PF05673.13 OQS03052.1 - 0.15 11.2 0.0 0.29 10.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Peptidase_M8 PF01457.16 OQS03053.1 - 1.7e-73 248.2 4.0 1.7e-73 248.2 4.0 1.8 2 0 0 2 2 2 1 Leishmanolysin EGF_2 PF07974.13 OQS03053.1 - 1.2e-18 67.2 95.6 2.7e-05 24.4 10.0 7.7 6 1 0 6 6 6 6 EGF-like domain EGF PF00008.27 OQS03053.1 - 3.1 8.2 85.6 0.049 14.0 7.5 7.6 6 1 0 6 6 6 0 EGF-like domain SKN1 PF03935.15 OQS03054.1 - 6.2e-72 242.6 31.4 1.2e-26 93.2 1.8 6.9 6 2 0 6 6 6 6 Beta-glucan synthesis-associated protein (SKN1) EB PF01683.18 OQS03054.1 - 0.0011 19.2 11.7 0.11 12.8 0.9 3.6 4 0 0 4 4 4 2 EB module DUF5454 PF17535.2 OQS03054.1 - 0.034 13.5 1.3 5.1 6.4 0.1 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5454) Nodulin_late PF07127.11 OQS03054.1 - 0.068 13.5 7.5 3.8 7.9 0.9 3.2 2 0 0 2 2 2 0 Late nodulin protein Cadherin_C_2 PF16492.5 OQS03054.1 - 0.096 13.4 1.7 2.3 9.0 0.0 3.6 4 0 0 4 4 4 0 Cadherin cytoplasmic C-terminal Integrin_b_cyt PF08725.11 OQS03054.1 - 0.25 11.0 1.0 15 5.3 0.1 2.5 2 0 0 2 2 2 0 Integrin beta cytoplasmic domain EGF_2 PF07974.13 OQS03054.1 - 7 7.1 23.1 3 8.3 8.1 3.4 2 0 0 2 2 2 0 EGF-like domain Ank_2 PF12796.7 OQS03055.1 - 2.1e-28 98.7 1.7 6e-13 49.2 0.0 4.1 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OQS03055.1 - 1e-23 80.8 1.3 0.0023 18.3 0.0 7.8 7 0 0 7 7 7 4 Ankyrin repeat Ank_4 PF13637.6 OQS03055.1 - 2.5e-19 69.4 2.1 3.3e-06 27.5 0.0 5.9 1 1 4 5 5 5 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 OQS03055.1 - 1.5e-15 57.1 1.3 1.7e-06 28.2 0.0 5.8 4 2 2 6 6 6 2 Ankyrin repeats (many copies) Ank PF00023.30 OQS03055.1 - 2.5e-15 56.2 6.3 0.00044 20.6 0.0 6.9 8 1 0 8 8 8 3 Ankyrin repeat Pkinase_Tyr PF07714.17 OQS03055.1 - 7.4e-13 48.4 0.0 1.2e-11 44.4 0.0 2.3 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.25 OQS03055.1 - 2.7e-10 40.1 0.0 3.9e-07 29.7 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain NAT PF04768.13 OQS03055.1 - 0.026 14.2 0.0 0.074 12.7 0.0 1.7 2 0 0 2 2 2 0 NAT, N-acetyltransferase, of N-acetylglutamate synthase DED PF01335.21 OQS03055.1 - 0.079 13.3 1.7 0.35 11.2 1.7 2.1 2 0 0 2 2 2 0 Death effector domain LRR_4 PF12799.7 OQS03055.1 - 0.42 11.1 4.7 1.3 9.5 0.4 2.9 2 0 0 2 2 2 0 Leucine Rich repeats (2 copies) Sororin PF09666.10 OQS03056.1 - 0.013 15.7 1.1 0.027 14.7 1.1 1.6 1 1 0 1 1 1 0 Sororin protein TraY PF05509.11 OQS03056.1 - 0.047 13.7 0.3 0.094 12.8 0.3 1.5 1 0 0 1 1 1 0 TraY domain Ank_2 PF12796.7 OQS03057.1 - 4e-96 315.7 52.7 6.5e-19 68.3 0.1 8.4 2 1 9 11 11 11 11 Ankyrin repeats (3 copies) Ank PF00023.30 OQS03057.1 - 4.6e-55 181.8 28.1 9.8e-06 25.8 0.1 13.7 12 1 1 13 13 13 12 Ankyrin repeat Ank_4 PF13637.6 OQS03057.1 - 7.3e-50 166.7 15.6 4e-08 33.6 0.1 10.2 7 3 4 11 11 11 8 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQS03057.1 - 5.5e-48 155.4 19.8 0.00074 19.8 0.0 14.5 15 0 0 15 15 15 10 Ankyrin repeat Pkinase PF00069.25 OQS03057.1 - 7.5e-47 159.9 0.1 9.4e-46 156.3 0.0 2.3 3 0 0 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQS03057.1 - 5.1e-46 157.1 0.0 2.1e-45 155.0 0.0 2.0 3 0 0 3 3 3 1 Protein tyrosine kinase Ank_5 PF13857.6 OQS03057.1 - 2.1e-38 129.9 23.4 1.6e-06 28.3 0.3 9.7 6 2 4 10 10 10 8 Ankyrin repeats (many copies) Haspin_kinase PF12330.8 OQS03057.1 - 0.0023 16.9 0.4 0.0051 15.8 0.0 1.7 2 0 0 2 2 2 1 Haspin like kinase domain Pkinase_fungal PF17667.1 OQS03057.1 - 0.019 13.8 0.0 0.031 13.1 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Kdo PF06293.14 OQS03057.1 - 0.021 14.2 0.0 0.037 13.4 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF410 PF04190.13 OQS03058.1 - 3e-43 148.5 1.5 3.9e-43 148.1 1.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF410) VasI PF11319.8 OQS03058.1 - 0.018 14.7 0.0 0.031 13.9 0.0 1.4 1 1 0 1 1 1 0 Type VI secretion system VasI, EvfG, VC_A0118 Vps54_N PF10475.9 OQS03058.1 - 0.028 13.7 0.1 2 7.7 0.0 2.2 1 1 1 2 2 2 0 Vacuolar-sorting protein 54, of GARP complex TPR_12 PF13424.6 OQS03058.1 - 0.043 14.1 4.9 0.84 10.0 1.5 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.6 OQS03058.1 - 0.11 13.1 7.2 0.99 10.0 0.0 3.1 3 1 1 4 4 4 0 Tetratricopeptide repeat Uricase PF01014.18 OQS03059.1 - 2.4e-50 170.2 0.0 1.5e-24 86.7 0.0 2.1 2 0 0 2 2 2 2 Uricase FolB PF02152.18 OQS03059.1 - 0.038 14.5 0.1 0.14 12.7 0.1 1.9 2 0 0 2 2 2 0 Dihydroneopterin aldolase Mvb12 PF09452.10 OQS03059.1 - 0.19 12.2 0.0 0.47 10.9 0.0 1.7 1 0 0 1 1 1 0 ESCRT-I subunit Mvb12 GDI PF00996.18 OQS03060.1 - 3.8e-54 183.9 0.0 2.5e-23 82.3 0.0 3.1 1 1 2 3 3 3 3 GDP dissociation inhibitor Complex1_LYR PF05347.15 OQS03060.1 - 2.9e-05 24.0 0.0 4.8e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 Complex 1 protein (LYR family) DAO PF01266.24 OQS03060.1 - 0.016 14.8 0.0 0.91 9.0 0.0 2.3 2 0 0 2 2 2 0 FAD dependent oxidoreductase UDPG_MGDP_dh_N PF03721.14 OQS03060.1 - 0.099 12.2 2.9 0.62 9.6 0.7 2.3 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_binding_8 PF13450.6 OQS03060.1 - 0.19 12.0 0.2 0.61 10.4 0.0 1.9 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Pkinase PF00069.25 OQS03061.1 - 2.1e-47 161.7 0.0 2.8e-47 161.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQS03061.1 - 6e-46 156.8 0.0 8.2e-46 156.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 OQS03061.1 - 0.018 15.0 0.1 0.028 14.3 0.1 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 OQS03061.1 - 0.019 13.7 0.0 0.026 13.3 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase Haspin_kinase PF12330.8 OQS03061.1 - 0.08 11.9 0.1 0.27 10.1 0.0 1.7 2 0 0 2 2 2 0 Haspin like kinase domain gag-asp_proteas PF13975.6 OQS03062.1 - 0.002 18.6 0.0 0.0024 18.4 0.0 1.2 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 OQS03062.1 - 0.094 13.4 0.0 0.12 13.0 0.0 1.2 1 0 0 1 1 1 0 Aspartyl protease DUF3042 PF11240.8 OQS03062.1 - 0.13 12.3 0.5 0.22 11.6 0.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3042) SKN1 PF03935.15 OQS03063.1 - 1.8e-121 406.0 47.4 7.3e-24 84.0 3.6 9.4 8 2 0 8 8 8 8 Beta-glucan synthesis-associated protein (SKN1) EB PF01683.18 OQS03063.1 - 3.5e-05 24.0 9.6 0.063 13.6 1.4 2.9 2 0 0 2 2 2 2 EB module Nodulin_late PF07127.11 OQS03063.1 - 0.0031 17.8 7.8 0.63 10.4 1.0 2.7 2 0 0 2 2 2 2 Late nodulin protein DUF3889 PF13028.6 OQS03063.1 - 0.0063 16.4 0.0 6.2 6.8 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF3889) DUF1799 PF08809.11 OQS03063.1 - 0.014 15.5 2.5 5.5 7.2 0.2 2.8 2 0 0 2 2 2 0 Phage related hypothetical protein (DUF1799) ThiS PF02597.20 OQS03063.1 - 0.024 15.3 0.0 15 6.3 0.0 2.5 2 0 0 2 2 2 0 ThiS family DKCLD PF08068.12 OQS03063.1 - 0.038 14.1 0.6 14 5.8 0.1 2.6 2 0 0 2 2 2 0 DKCLD (NUC011) domain DUF5454 PF17535.2 OQS03063.1 - 0.85 9.0 6.5 6.8 6.0 0.1 2.7 4 0 0 4 4 4 0 Family of unknown function (DUF5454) ABC_membrane PF00664.23 OQS03064.1 - 2e-53 181.8 10.3 3.3e-53 181.1 10.3 1.3 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 OQS03064.1 - 1.1e-15 58.4 0.0 1.9e-15 57.6 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_29 PF13555.6 OQS03064.1 - 0.0036 17.0 0.2 0.0097 15.6 0.2 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain G-alpha PF00503.20 OQS03064.1 - 0.017 14.3 0.0 0.028 13.6 0.0 1.2 1 0 0 1 1 1 0 G-protein alpha subunit Zeta_toxin PF06414.12 OQS03064.1 - 0.02 14.2 0.0 0.036 13.3 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_25 PF13481.6 OQS03064.1 - 0.052 13.1 0.0 0.094 12.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain APS_kinase PF01583.20 OQS03064.1 - 0.056 13.3 0.0 0.13 12.1 0.0 1.6 1 0 0 1 1 1 0 Adenylylsulphate kinase DUF87 PF01935.17 OQS03064.1 - 0.072 13.2 0.0 0.11 12.5 0.0 1.3 1 0 0 1 1 1 0 Helicase HerA, central domain YwiC PF14256.6 OQS03064.1 - 0.076 13.3 1.5 0.2 12.0 0.2 2.2 2 0 0 2 2 2 0 YwiC-like protein RsgA_GTPase PF03193.16 OQS03064.1 - 0.079 12.9 0.0 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase AAA_15 PF13175.6 OQS03064.1 - 0.089 12.5 0.0 0.14 11.9 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 OQS03064.1 - 0.091 13.0 0.0 0.18 12.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 OQS03064.1 - 0.11 12.3 0.0 0.17 11.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 OQS03064.1 - 0.14 12.5 0.0 0.26 11.7 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain AAA_7 PF12775.7 OQS03064.1 - 0.15 11.5 0.0 0.42 10.1 0.0 1.7 1 0 0 1 1 1 0 P-loop containing dynein motor region Ni_hydr_CYTB PF01292.20 OQS03064.1 - 0.34 10.5 3.4 1.6 8.3 3.2 2.4 1 1 0 1 1 1 0 Prokaryotic cytochrome b561 ABC_membrane PF00664.23 OQS03065.1 - 3e-52 178.0 11.0 3.8e-52 177.6 11.0 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 OQS03065.1 - 7.1e-35 120.5 0.0 1.2e-34 119.8 0.0 1.4 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 OQS03065.1 - 3.8e-05 23.2 0.3 0.0019 17.7 0.0 2.1 1 1 1 2 2 2 1 RecF/RecN/SMC N terminal domain Zeta_toxin PF06414.12 OQS03065.1 - 0.00096 18.5 0.0 0.0019 17.5 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin ABC_ATPase PF09818.9 OQS03065.1 - 0.0048 15.8 0.4 0.025 13.4 0.1 1.9 2 0 0 2 2 2 1 Predicted ATPase of the ABC class AAA_29 PF13555.6 OQS03065.1 - 0.0065 16.2 0.0 0.014 15.1 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.6 OQS03065.1 - 0.0091 16.4 0.1 0.019 15.3 0.1 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_15 PF13175.6 OQS03065.1 - 0.015 15.1 0.0 0.02 14.6 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 OQS03065.1 - 0.015 15.6 0.1 0.08 13.2 0.1 2.0 1 1 0 1 1 1 0 AAA domain AAA_30 PF13604.6 OQS03065.1 - 0.019 14.7 0.6 0.059 13.1 0.6 1.9 1 1 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 OQS03065.1 - 0.025 14.5 0.0 0.051 13.5 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase AAA_21 PF13304.6 OQS03065.1 - 0.036 13.9 0.2 1.9 8.2 0.1 2.1 1 1 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system G-alpha PF00503.20 OQS03065.1 - 0.037 13.2 0.0 0.052 12.7 0.0 1.3 1 0 0 1 1 1 0 G-protein alpha subunit Ank_5 PF13857.6 OQS03067.1 - 1.2e-24 86.1 8.6 5e-05 23.5 0.1 6.9 1 1 6 7 7 7 7 Ankyrin repeats (many copies) Ank_2 PF12796.7 OQS03067.1 - 3.4e-20 72.4 5.8 9.8e-06 26.1 0.1 3.5 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQS03067.1 - 1.8e-17 63.5 2.8 5.3e-05 23.7 0.1 4.7 3 2 2 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQS03067.1 - 4.9e-11 41.9 0.6 0.53 11.0 0.0 6.6 6 1 1 7 7 7 1 Ankyrin repeat DUF5049 PF16468.5 OQS03067.1 - 2.7e-09 36.8 10.5 0.27 11.1 0.3 6.9 2 2 5 7 7 7 4 Domain of unknown function (DUF5049) VHL_C PF17211.3 OQS03067.1 - 0.00055 19.9 0.2 14 5.8 0.0 5.1 6 0 0 6 6 6 1 VHL box domain FAM195 PF14799.6 OQS03067.1 - 0.00091 19.5 3.1 9.3 6.7 0.1 4.7 1 1 4 5 5 5 1 FAM195 family Tom37 PF10568.9 OQS03067.1 - 0.0011 19.2 0.2 4.9 7.5 0.0 4.4 1 1 2 3 3 3 1 Outer mitochondrial membrane transport complex protein Helicase_PWI PF18149.1 OQS03067.1 - 0.0043 17.2 1.9 8 6.7 0.0 4.1 1 1 2 4 4 4 1 N-terminal helicase PWI domain Ank PF00023.30 OQS03067.1 - 0.0074 16.7 0.1 48 4.6 0.0 4.8 3 1 0 3 3 3 0 Ankyrin repeat Tyosinase_C PF18132.1 OQS03067.1 - 0.0095 16.6 0.2 0.088 13.5 0.1 2.2 1 1 2 3 3 3 1 Tyosinase C-terminal domain DUF190 PF02641.15 OQS03067.1 - 0.014 15.7 0.1 21 5.5 0.0 4.6 2 1 4 6 6 6 0 Uncharacterized ACR, COG1993 VbhA PF18495.1 OQS03067.1 - 0.087 12.7 0.5 8.5 6.3 0.0 3.7 5 0 0 5 5 5 0 Antitoxin VbhA Peptidase_M20 PF01546.28 OQS03068.1 - 1.8e-07 31.0 0.0 1.9e-07 31.0 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 OQS03068.1 - 0.00045 20.1 0.5 0.0026 17.6 0.5 2.0 1 1 0 1 1 1 1 Peptidase dimerisation domain Methyltransf_16 PF10294.9 OQS03069.1 - 1.4e-29 103.1 0.0 1.6e-29 102.8 0.0 1.0 1 0 0 1 1 1 1 Lysine methyltransferase MTS PF05175.14 OQS03069.1 - 0.00029 20.4 0.0 0.00038 20.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.13 OQS03069.1 - 0.00034 20.1 0.1 0.00046 19.7 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.6 OQS03069.1 - 0.012 16.3 0.0 0.019 15.6 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.6 OQS03069.1 - 0.026 14.3 0.0 0.033 14.0 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain GidB PF02527.15 OQS03069.1 - 0.11 11.8 0.0 0.15 11.4 0.0 1.2 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G Methyltransf_23 PF13489.6 OQS03069.1 - 0.15 11.8 0.0 0.31 10.9 0.0 1.5 2 0 0 2 2 2 0 Methyltransferase domain HA PF03457.14 OQS03070.1 - 2.8e-36 123.7 5.1 1.5e-12 47.7 0.2 5.3 5 0 0 5 5 5 4 Helicase associated domain DUF4116 PF13475.6 OQS03070.1 - 0.091 12.5 0.2 4.9 7.0 0.1 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4116) Pepsin-I3 PF06394.13 OQS03070.1 - 0.093 12.9 0.4 0.2 11.8 0.1 1.8 2 0 0 2 2 2 0 Pepsin inhibitor-3-like repeated domain PDEase_I PF00233.19 OQS03071.1 - 5e-60 203.2 0.0 9e-60 202.3 0.0 1.5 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase GAF PF01590.26 OQS03071.1 - 4e-11 43.7 0.9 0.00091 19.9 0.1 3.8 4 0 0 4 4 4 2 GAF domain GAF_2 PF13185.6 OQS03071.1 - 2.5e-06 27.8 0.0 0.099 12.9 0.0 3.3 3 0 0 3 3 3 2 GAF domain DUF3247 PF11607.8 OQS03071.1 - 0.2 11.9 1.3 0.66 10.3 0.0 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3247) Mut7-C PF01927.16 OQS03072.1 - 3.3e-23 82.4 0.8 3.3e-23 82.4 0.8 2.0 2 0 0 2 2 2 1 Mut7-C RNAse domain DNA_pol_A_exo1 PF01612.20 OQS03072.1 - 1.2e-16 60.9 0.0 3.2e-16 59.5 0.0 1.7 1 0 0 1 1 1 1 3'-5' exonuclease tRNA_edit PF04073.15 OQS03072.1 - 1.6e-14 54.1 0.1 4.7e-14 52.5 0.0 1.8 2 0 0 2 2 2 1 Aminoacyl-tRNA editing domain DUF5615 PF18480.1 OQS03072.1 - 0.0082 15.9 0.1 0.023 14.4 0.1 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF5615) DUF4946 PF16304.5 OQS03072.1 - 0.13 11.9 0.2 2.6 7.7 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4946) TPR_11 PF13414.6 OQS03073.1 - 1.4e-17 63.1 4.4 8e-08 31.8 0.0 4.6 4 1 1 5 5 5 3 TPR repeat TPR_1 PF00515.28 OQS03073.1 - 2.1e-11 43.1 7.3 0.0024 17.6 0.0 7.1 7 1 0 7 7 7 2 Tetratricopeptide repeat TPR_2 PF07719.17 OQS03073.1 - 3.4e-09 36.1 8.7 0.38 11.0 0.0 6.9 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_17 PF13431.6 OQS03073.1 - 2.3e-08 33.8 4.9 0.0095 16.3 0.0 5.2 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.6 OQS03073.1 - 4e-05 24.2 0.9 0.97 10.1 0.0 3.5 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 OQS03073.1 - 0.0001 22.8 2.7 2.1 9.4 0.0 5.0 2 2 4 6 6 6 1 Tetratricopeptide repeat TPR_6 PF13174.6 OQS03073.1 - 0.031 14.9 1.7 58 4.6 0.0 4.5 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_8 PF13181.6 OQS03073.1 - 0.031 14.5 11.9 0.67 10.3 0.0 6.2 7 0 0 7 7 7 0 Tetratricopeptide repeat FAT PF02259.23 OQS03073.1 - 0.05 12.8 5.8 0.18 11.0 4.0 2.1 1 1 1 2 2 2 0 FAT domain Ank_2 PF12796.7 OQS03074.1 - 1.4e-40 137.8 25.7 9.5e-11 42.1 0.7 6.8 2 2 7 9 9 9 8 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQS03074.1 - 5.4e-19 68.3 13.7 0.022 15.3 0.1 9.0 5 3 4 9 9 9 8 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQS03074.1 - 4.9e-16 57.2 8.9 0.2 12.3 0.0 11.6 11 1 1 12 12 12 2 Ankyrin repeat Ank_5 PF13857.6 OQS03074.1 - 1.3e-11 44.4 10.4 0.077 13.3 0.0 9.3 3 1 8 11 11 11 3 Ankyrin repeats (many copies) DUF3447 PF11929.8 OQS03074.1 - 2.1e-07 30.8 3.9 0.21 11.6 0.0 5.5 3 2 4 7 7 6 3 Domain of unknown function (DUF3447) Ank PF00023.30 OQS03074.1 - 4.4e-06 26.9 15.6 2.5 8.7 0.0 8.1 8 2 1 9 9 9 3 Ankyrin repeat LRR_6 PF13516.6 OQS03075.1 - 1.9e-14 52.4 19.9 9.4e-05 22.2 0.2 6.7 7 0 0 7 7 7 5 Leucine Rich repeat LRR_4 PF12799.7 OQS03075.1 - 2.1e-07 31.1 16.1 0.00094 19.5 0.7 4.9 4 1 2 6 6 6 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 OQS03075.1 - 0.014 15.1 12.3 0.47 10.3 2.1 4.6 3 2 0 3 3 3 0 Leucine rich repeat LRR_1 PF00560.33 OQS03075.1 - 1.8 9.4 14.3 31 5.6 0.0 6.1 6 1 0 6 6 6 0 Leucine Rich Repeat DOMON PF03351.17 OQS03076.1 - 6.3e-17 62.0 0.0 2.5e-10 40.6 0.0 2.2 2 0 0 2 2 2 2 DOMON domain EB_dh PF09459.10 OQS03076.1 - 0.0019 18.2 0.0 1.4 8.8 0.0 2.2 1 1 1 2 2 2 2 Ethylbenzene dehydrogenase LRR_6 PF13516.6 OQS03077.1 - 1.2e-10 40.5 7.5 3.1e-05 23.7 0.0 5.2 5 0 0 5 5 5 2 Leucine Rich repeat LRR_8 PF13855.6 OQS03077.1 - 6.9e-09 35.3 4.1 0.00018 21.2 0.0 4.8 4 1 1 5 5 5 2 Leucine rich repeat LRR_4 PF12799.7 OQS03077.1 - 2.4e-08 34.1 8.5 0.00035 20.9 0.0 6.0 7 0 0 7 7 7 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 OQS03077.1 - 0.035 14.6 5.0 2.9 8.8 0.0 5.2 5 1 0 5 5 5 0 Leucine Rich Repeat AnfO_nitrog PF09582.10 OQS03077.1 - 0.19 11.1 0.1 0.28 10.5 0.1 1.2 1 0 0 1 1 1 0 Iron only nitrogenase protein AnfO (AnfO_nitrog) LRR_6 PF13516.6 OQS03078.1 - 1.5e-14 52.7 13.4 0.0012 18.8 0.1 6.7 6 0 0 6 6 6 4 Leucine Rich repeat LRR_4 PF12799.7 OQS03078.1 - 1.1e-06 28.9 5.1 0.036 14.5 0.0 5.1 3 1 3 6 6 6 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 OQS03078.1 - 0.00011 21.9 8.5 0.14 11.9 0.9 4.4 4 1 1 5 5 5 3 Leucine rich repeat AftA_N PF12250.8 OQS03078.1 - 0.042 12.6 0.2 0.064 12.0 0.2 1.1 1 0 0 1 1 1 0 Arabinofuranosyltransferase N terminal BT1 PF03092.16 OQS03079.1 - 1e-12 47.1 17.2 2.3e-10 39.4 0.5 3.7 2 2 1 3 3 3 3 BT1 family MFS_1 PF07690.16 OQS03079.1 - 3.6e-05 22.8 41.3 0.0033 16.4 35.2 3.6 1 1 1 2 2 2 2 Major Facilitator Superfamily Phage_holin_Dp1 PF16938.5 OQS03079.1 - 0.15 12.3 8.1 0.13 12.4 4.8 2.5 2 0 0 2 2 2 0 Putative phage holin Dp-1 DUF4512 PF14975.6 OQS03079.1 - 0.21 12.4 0.3 0.45 11.3 0.3 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4512) Ank_2 PF12796.7 OQS03080.1 - 1.4e-28 99.3 0.1 1e-12 48.5 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OQS03080.1 - 7.5e-24 83.5 0.8 9.8e-07 28.9 0.0 4.6 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQS03080.1 - 3e-22 76.3 2.0 0.00011 22.3 0.1 4.8 4 0 0 4 4 4 4 Ankyrin repeat Ank PF00023.30 OQS03080.1 - 9.5e-22 76.4 3.7 1.4e-05 25.3 0.2 4.8 4 0 0 4 4 4 4 Ankyrin repeat Ank_4 PF13637.6 OQS03080.1 - 1.7e-17 63.5 1.6 5.5e-06 26.8 0.2 4.2 2 2 2 4 4 4 4 Ankyrin repeats (many copies) AAA_18 PF13238.6 OQS03080.1 - 9.4e-05 23.0 0.1 0.00087 19.8 0.0 2.9 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.14 OQS03080.1 - 0.0008 19.4 1.6 0.014 15.4 0.3 3.3 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 OQS03080.1 - 0.0019 18.4 1.7 0.0054 16.9 0.1 2.7 3 0 0 3 3 2 1 AAA domain DUF4030 PF13222.6 OQS03080.1 - 0.0025 18.0 0.1 0.0095 16.1 0.1 2.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4030) AAA_28 PF13521.6 OQS03080.1 - 0.0032 17.7 0.3 0.011 16.0 0.1 2.0 2 0 0 2 2 1 1 AAA domain Zeta_toxin PF06414.12 OQS03080.1 - 0.0034 16.7 0.2 0.011 15.0 0.0 1.9 2 0 0 2 2 2 1 Zeta toxin RsgA_GTPase PF03193.16 OQS03080.1 - 0.0044 16.9 0.3 0.027 14.4 0.0 2.5 3 0 0 3 3 3 1 RsgA GTPase AAA_16 PF13191.6 OQS03080.1 - 0.019 15.3 0.0 0.097 13.0 0.0 2.2 1 0 0 1 1 1 0 AAA ATPase domain APS_kinase PF01583.20 OQS03080.1 - 0.032 14.1 0.1 0.072 13.0 0.1 1.6 1 0 0 1 1 1 0 Adenylylsulphate kinase ABC_tran PF00005.27 OQS03080.1 - 0.042 14.4 0.0 0.28 11.7 0.0 2.5 1 0 0 1 1 1 0 ABC transporter AAA_25 PF13481.6 OQS03080.1 - 0.042 13.4 0.0 0.13 11.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain CbiA PF01656.23 OQS03080.1 - 0.071 13.2 0.0 0.2 11.7 0.0 1.8 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA PF00004.29 OQS03080.1 - 0.077 13.4 0.0 0.35 11.3 0.0 2.2 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.6 OQS03080.1 - 0.11 12.3 0.1 0.28 11.0 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Pkinase PF00069.25 OQS03082.1 - 3.6e-151 501.9 0.0 1e-49 169.3 0.0 3.1 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 OQS03082.1 - 3.6e-80 269.0 0.0 1e-26 93.8 0.0 3.3 3 0 0 3 3 3 3 Protein tyrosine kinase Kinase-like PF14531.6 OQS03082.1 - 3e-07 30.0 0.6 0.0098 15.2 0.0 3.6 4 0 0 4 4 4 2 Kinase-like Kdo PF06293.14 OQS03082.1 - 1.6e-06 27.6 0.2 0.74 9.1 0.0 3.6 3 0 0 3 3 3 3 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 OQS03082.1 - 0.00016 21.4 0.1 0.49 10.0 0.0 3.4 3 0 0 3 3 3 2 RIO1 family Pkinase_fungal PF17667.1 OQS03082.1 - 0.00053 18.9 0.1 0.85 8.3 0.0 3.1 3 0 0 3 3 3 2 Fungal protein kinase APH PF01636.23 OQS03082.1 - 0.015 15.2 3.7 4.4 7.1 0.0 4.0 4 1 0 4 4 4 0 Phosphotransferase enzyme family TPT PF03151.16 OQS03083.1 - 5.5e-09 35.8 22.3 6.6e-09 35.5 22.3 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 OQS03083.1 - 0.0019 18.4 10.2 0.0019 18.4 10.2 2.2 2 0 0 2 2 2 1 EamA-like transporter family GPI-anchored PF10342.9 OQS03084.1 - 0.0034 18.1 0.0 0.0071 17.1 0.0 1.6 2 0 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Pkinase_Tyr PF07714.17 OQS03085.1 - 6e-44 150.3 0.0 1e-43 149.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OQS03085.1 - 1.9e-43 148.7 0.0 3.1e-43 148.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Adeno_E3_CR2 PF02439.15 OQS03085.1 - 2.3e-05 24.0 1.9 5.5e-05 22.8 1.9 1.5 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 SKG6 PF08693.10 OQS03085.1 - 0.00026 20.3 6.8 0.00045 19.6 6.8 1.4 1 0 0 1 1 1 1 Transmembrane alpha-helix domain EphA2_TM PF14575.6 OQS03085.1 - 0.00051 20.9 0.0 0.0012 19.7 0.0 1.6 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain T4SS_CagC PF16943.5 OQS03085.1 - 0.00084 19.5 0.4 0.0018 18.4 0.4 1.4 1 0 0 1 1 1 1 Cag pathogenicity island, type IV secretory system TMEM154 PF15102.6 OQS03085.1 - 0.0024 17.8 0.0 0.0048 16.8 0.0 1.4 1 0 0 1 1 1 1 TMEM154 protein family Amnionless PF14828.6 OQS03085.1 - 0.035 12.9 0.1 0.54 9.0 0.0 2.1 2 0 0 2 2 2 0 Amnionless TMEM51 PF15345.6 OQS03085.1 - 0.038 13.8 0.0 0.07 13.0 0.0 1.3 1 0 0 1 1 1 0 Transmembrane protein 51 ECSCR PF15820.5 OQS03085.1 - 0.064 13.1 0.2 0.18 11.6 0.2 1.8 1 0 0 1 1 1 0 Endothelial cell-specific chemotaxis regulator MGC-24 PF05283.11 OQS03085.1 - 0.086 13.3 5.6 0.52 10.7 0.9 2.3 2 0 0 2 2 2 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin Syndecan PF01034.20 OQS03085.1 - 0.094 12.6 0.0 0.19 11.7 0.0 1.4 1 0 0 1 1 1 0 Syndecan domain DAP10 PF07213.11 OQS03085.1 - 0.1 12.5 0.1 0.24 11.4 0.1 1.5 1 0 0 1 1 1 0 DAP10 membrane protein Mid2 PF04478.12 OQS03085.1 - 0.14 12.0 1.8 0.26 11.1 1.8 1.3 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor APH PF01636.23 OQS03085.1 - 0.15 11.9 0.0 0.36 10.7 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family RIFIN PF02009.16 OQS03085.1 - 0.17 11.7 0.0 0.3 11.0 0.0 1.3 1 0 0 1 1 1 0 Rifin Insulin_TMD PF17870.1 OQS03085.1 - 0.2 11.7 1.7 0.52 10.4 1.7 1.6 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment Pkinase_fungal PF17667.1 OQS03085.1 - 0.21 10.3 0.0 0.32 9.7 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase CYYR1 PF10873.8 OQS03085.1 - 2.6 8.5 8.5 6.7 7.1 8.4 1.7 1 1 0 1 1 1 0 Cysteine and tyrosine-rich protein 1 NRDE-2 PF08424.10 OQS03086.1 - 2.6e-16 59.7 4.8 2.6e-16 59.7 4.8 1.4 2 0 0 2 2 2 1 NRDE-2, necessary for RNA interference NapB PF03892.14 OQS03086.1 - 0.65 10.0 2.9 0.69 9.9 0.7 2.0 2 0 0 2 2 2 0 Nitrate reductase cytochrome c-type subunit (NapB) Pkinase PF00069.25 OQS03087.1 - 7.4e-43 146.8 0.0 1.3e-42 146.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQS03087.1 - 4.3e-39 134.4 0.0 7.7e-39 133.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OQS03087.1 - 0.0012 17.7 0.0 0.0019 17.1 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase B_lectin PF01453.24 OQS03087.1 - 0.0032 18.0 0.4 0.036 14.6 0.3 2.5 1 1 1 2 2 2 1 D-mannose binding lectin APH PF01636.23 OQS03087.1 - 0.0075 16.2 0.0 0.011 15.6 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family EphA2_TM PF14575.6 OQS03087.1 - 0.041 14.8 0.0 0.097 13.6 0.0 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain TatD_DNase PF01026.21 OQS03089.1 - 1.5e-56 191.6 0.0 1.8e-56 191.4 0.0 1.0 1 0 0 1 1 1 1 TatD related DNase Radical_SAM PF04055.21 OQS03089.1 - 0.023 15.1 0.0 0.056 13.8 0.0 1.8 1 1 0 1 1 1 0 Radical SAM superfamily DEAD PF00270.29 OQS03090.1 - 4.6e-17 62.3 0.0 8.4e-17 61.5 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OQS03090.1 - 2.8e-15 56.6 0.0 8.4e-14 51.9 0.0 2.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain RecQ_Zn_bind PF16124.5 OQS03090.1 - 1e-11 45.4 3.5 1e-11 45.4 3.5 2.2 2 0 0 2 2 2 1 RecQ zinc-binding RQC PF09382.10 OQS03090.1 - 0.0032 17.2 0.2 0.0073 16.1 0.2 1.6 1 0 0 1 1 1 1 RQC domain ResIII PF04851.15 OQS03090.1 - 0.0073 16.3 0.0 0.017 15.2 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Choline_kin_N PF04428.14 OQS03090.1 - 0.23 11.2 0.6 9.9 5.9 0.0 3.1 3 0 0 3 3 3 0 Choline kinase N terminus TIR_2 PF13676.6 OQS03091.1 - 4e-13 50.0 0.0 1e-12 48.7 0.0 1.7 1 0 0 1 1 1 1 TIR domain SAM_2 PF07647.17 OQS03091.1 - 1e-07 31.9 0.0 2.6e-07 30.6 0.0 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 OQS03091.1 - 8.2e-06 26.2 0.6 9.2e-05 22.8 0.1 2.6 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) TIR PF01582.20 OQS03091.1 - 0.00011 22.1 0.0 0.00025 20.9 0.0 1.6 1 0 0 1 1 1 1 TIR domain Peptidase_S10 PF00450.22 OQS03092.1 - 7.6e-127 424.2 3.6 9.5e-127 423.9 3.6 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase DASH_Dad2 PF08654.10 OQS03093.1 - 8.6e-07 29.3 0.5 1e-06 29.1 0.5 1.1 1 0 0 1 1 1 1 DASH complex subunit Dad2 DASH_Duo1 PF08651.10 OQS03093.1 - 0.0058 16.4 1.2 0.0067 16.2 1.2 1.1 1 0 0 1 1 1 1 DASH complex subunit Duo1 DUF5327 PF17261.2 OQS03093.1 - 0.028 15.2 0.3 0.031 15.0 0.3 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5327) DUF4381 PF14316.6 OQS03094.1 - 5.2 7.3 7.5 0.52 10.5 0.7 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) DUF2530 PF10745.9 OQS03094.1 - 8.6 6.7 12.5 7.6 6.8 5.9 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2530) HisG PF01634.18 OQS03095.1 - 3.1e-55 186.5 0.1 3.9e-55 186.2 0.1 1.1 1 0 0 1 1 1 1 ATP phosphoribosyltransferase HisG_C PF08029.11 OQS03095.1 - 1.9e-12 47.2 0.0 3.7e-12 46.2 0.0 1.5 1 0 0 1 1 1 1 HisG, C-terminal domain SBP_bac_3 PF00497.20 OQS03095.1 - 0.0031 17.0 0.0 0.0049 16.3 0.0 1.3 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 DoxX PF07681.12 OQS03095.1 - 0.06 13.9 0.0 0.11 13.1 0.0 1.5 1 1 0 1 1 1 0 DoxX ADK PF00406.22 OQS03096.1 - 1.9e-31 109.2 0.0 3.3e-31 108.4 0.0 1.3 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 OQS03096.1 - 2.5e-21 76.5 0.0 5.9e-21 75.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 OQS03096.1 - 1.7e-08 34.8 0.1 7.3e-08 32.7 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 OQS03096.1 - 4.2e-07 30.6 0.0 1e-06 29.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain Cytidylate_kin PF02224.18 OQS03096.1 - 8e-05 22.5 0.3 0.00031 20.5 0.0 2.1 2 0 0 2 2 2 1 Cytidylate kinase AAA_28 PF13521.6 OQS03096.1 - 0.0024 18.1 0.0 0.005 17.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain NACHT PF05729.12 OQS03096.1 - 0.0025 17.8 0.0 0.0039 17.1 0.0 1.4 1 0 0 1 1 1 1 NACHT domain AAA PF00004.29 OQS03096.1 - 0.0026 18.2 0.0 0.0053 17.2 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Thymidylate_kin PF02223.17 OQS03096.1 - 0.0026 17.4 1.3 0.012 15.3 0.0 2.6 3 1 1 4 4 4 1 Thymidylate kinase NTPase_1 PF03266.15 OQS03096.1 - 0.0076 16.2 0.0 0.016 15.1 0.0 1.6 1 0 0 1 1 1 1 NTPase RNA_helicase PF00910.22 OQS03096.1 - 0.0098 16.3 0.0 0.028 14.8 0.0 1.8 2 0 0 2 2 1 1 RNA helicase AAA_16 PF13191.6 OQS03096.1 - 0.011 16.2 0.1 0.021 15.2 0.1 1.8 1 1 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 OQS03096.1 - 0.011 16.0 0.0 0.025 14.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain RuvB_N PF05496.12 OQS03096.1 - 0.018 14.8 0.0 0.031 14.0 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 OQS03096.1 - 0.032 14.2 0.0 0.069 13.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) TsaE PF02367.17 OQS03096.1 - 0.039 13.9 0.0 0.082 12.9 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE SKI PF01202.22 OQS03096.1 - 0.074 13.2 0.1 0.21 11.7 0.1 1.8 1 0 0 1 1 1 0 Shikimate kinase Mg_chelatase PF01078.21 OQS03096.1 - 0.081 12.3 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI PH_12 PF16457.5 OQS03096.1 - 0.09 13.3 0.0 0.22 12.1 0.0 1.7 1 0 0 1 1 1 0 Pleckstrin homology domain Hydin_ADK PF17213.3 OQS03096.1 - 0.095 13.0 0.1 5.5 7.2 0.0 2.5 1 1 1 2 2 2 0 Hydin Adenylate kinase-like domain AAA_11 PF13086.6 OQS03096.1 - 0.13 12.0 1.3 0.31 10.8 1.3 1.8 1 1 0 1 1 1 0 AAA domain Ank_2 PF12796.7 OQS03097.1 - 9e-23 80.7 6.0 2.7e-10 40.7 0.2 3.8 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OQS03097.1 - 1.4e-21 76.2 5.3 0.0019 18.5 0.0 7.0 2 2 5 7 7 7 5 Ankyrin repeats (many copies) Ank_4 PF13637.6 OQS03097.1 - 4.3e-21 75.0 2.1 0.00036 21.0 0.3 6.2 5 2 3 8 8 8 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQS03097.1 - 3.9e-12 45.2 1.1 2.3 9.1 0.0 6.8 7 0 0 7 7 7 4 Ankyrin repeat DUF5049 PF16468.5 OQS03097.1 - 1.1e-06 28.4 0.5 7.8 6.5 0.0 6.1 4 3 2 6 6 6 1 Domain of unknown function (DUF5049) Ank PF00023.30 OQS03097.1 - 0.0058 17.0 1.6 37 5.0 0.1 4.6 4 1 0 4 4 4 0 Ankyrin repeat Mononeg_RNA_pol PF00946.19 OQS03097.1 - 0.083 10.5 0.1 0.1 10.2 0.1 1.1 1 0 0 1 1 1 0 Mononegavirales RNA dependent RNA polymerase 4HBT_2 PF13279.6 OQS03097.1 - 0.095 13.2 0.0 8.6 6.9 0.0 2.6 1 1 1 2 2 2 0 Thioesterase-like superfamily TSLP PF15216.6 OQS03097.1 - 0.44 10.8 3.0 2.4 8.5 1.3 2.7 1 1 2 3 3 3 0 Thymic stromal lymphopoietin Methyltransf_25 PF13649.6 OQS03098.1 - 5e-17 62.4 0.0 2.9e-16 60.0 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 OQS03098.1 - 9e-14 51.5 0.0 1.2e-13 51.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OQS03098.1 - 2.4e-13 50.5 0.0 5.6e-13 49.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OQS03098.1 - 1.8e-11 44.6 0.0 9.6e-11 42.3 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 OQS03098.1 - 2.6e-10 40.4 0.0 3.8e-10 39.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 OQS03098.1 - 5.9e-09 35.7 0.0 8.8e-09 35.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Ubie_methyltran PF01209.18 OQS03098.1 - 8.5e-05 22.0 0.0 0.00014 21.3 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_2 PF00891.18 OQS03098.1 - 0.00011 21.6 0.0 0.00017 21.0 0.0 1.4 1 0 0 1 1 1 1 O-methyltransferase domain CMAS PF02353.20 OQS03098.1 - 0.00036 19.9 0.0 0.00055 19.3 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase DUF938 PF06080.12 OQS03098.1 - 0.00056 19.7 0.0 0.0032 17.2 0.0 2.0 1 1 1 2 2 2 1 Protein of unknown function (DUF938) FtsJ PF01728.19 OQS03098.1 - 0.0013 18.8 0.0 0.0057 16.8 0.0 1.8 1 1 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_32 PF13679.6 OQS03098.1 - 0.004 17.2 0.0 0.0059 16.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain NodS PF05401.11 OQS03098.1 - 0.01 15.4 0.0 0.038 13.6 0.0 1.8 1 1 1 2 2 2 0 Nodulation protein S (NodS) Methyltransf_5 PF01795.19 OQS03098.1 - 0.041 13.4 0.0 0.17 11.4 0.0 1.8 2 0 0 2 2 2 0 MraW methylase family CheR PF01739.18 OQS03098.1 - 0.076 12.5 0.0 2.6 7.5 0.0 2.2 1 1 1 2 2 2 0 CheR methyltransferase, SAM binding domain Methyltransf_PK PF05891.12 OQS03098.1 - 0.077 12.5 0.0 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 AdoMet dependent proline di-methyltransferase Methyltransf_33 PF10017.9 OQS03098.1 - 0.11 11.7 0.0 0.16 11.1 0.0 1.3 1 0 0 1 1 1 0 Histidine-specific methyltransferase, SAM-dependent ARID PF01388.21 OQS03099.1 - 1e-09 38.9 0.0 3e-09 37.4 0.0 1.8 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain BAF250_C PF12031.8 OQS03099.1 - 0.014 14.7 0.1 2 7.7 0.0 2.6 2 0 0 2 2 2 0 SWI/SNF-like complex subunit BAF250/Osa Img2 PF05046.14 OQS03100.1 - 3.3e-17 62.5 0.0 5.1e-17 61.9 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial large subunit ribosomal protein (Img2) SUI1 PF01253.22 OQS03100.1 - 0.0089 16.5 0.0 0.013 16.0 0.0 1.3 1 0 0 1 1 1 1 Translation initiation factor SUI1 BT1 PF03092.16 OQS03101.1 - 2.2e-21 75.7 11.4 4.4e-19 68.1 1.8 2.6 2 0 0 2 2 2 2 BT1 family DHHC PF01529.20 OQS03101.1 - 7.1e-17 61.8 5.1 7.1e-17 61.8 5.1 4.9 5 1 0 6 6 6 1 DHHC palmitoyltransferase DUF1290 PF06947.12 OQS03101.1 - 6.5 6.9 7.7 2.2 8.5 0.0 4.0 5 0 0 5 5 5 0 Protein of unknown function (DUF1290) Stealth_CR2 PF11380.8 OQS03102.1 - 1.1e-45 154.2 0.5 9.4e-44 148.0 0.1 2.6 2 0 0 2 2 2 1 Stealth protein CR2, conserved region 2 Stealth_CR3 PF17102.5 OQS03102.1 - 7.9e-18 64.1 8.3 7.9e-18 64.1 8.3 2.0 2 0 0 2 2 2 1 Stealth protein CR3, conserved region 3 Notch PF00066.17 OQS03102.1 - 1.3e-12 47.9 29.9 3.6e-06 27.3 12.4 2.6 2 0 0 2 2 2 2 LNR domain Stealth_CR1 PF17101.5 OQS03102.1 - 3.3e-11 42.7 0.9 6.5e-11 41.8 0.9 1.4 1 0 0 1 1 1 1 Stealth protein CR1, conserved region 1 Stealth_CR4 PF17103.5 OQS03102.1 - 9.3e-11 41.5 0.2 2.7e-10 40.0 0.0 1.9 2 0 0 2 2 2 1 Stealth protein CR4, conserved region 4 APC1_C PF18122.1 OQS03102.1 - 0.13 12.2 0.0 0.64 9.9 0.0 2.1 2 0 0 2 2 2 0 Anaphase-promoting complex sub unit 1 C-terminal domain K-cyclin_vir_C PF09080.10 OQS03102.1 - 0.17 12.3 0.1 0.38 11.2 0.1 1.5 1 0 0 1 1 1 0 K cyclin, C terminal Stealth_CR3 PF17102.5 OQS03103.1 - 4.7e-05 23.2 0.1 0.0001 22.2 0.1 1.6 1 0 0 1 1 1 1 Stealth protein CR3, conserved region 3 Notch PF00066.17 OQS03103.1 - 0.00027 21.3 7.3 0.00077 19.9 7.3 1.9 1 0 0 1 1 1 1 LNR domain EF-hand_6 PF13405.6 OQS03103.1 - 0.055 13.4 0.0 0.12 12.3 0.0 1.6 1 0 0 1 1 1 0 EF-hand domain EF-hand_7 PF13499.6 OQS03103.1 - 0.094 13.2 0.0 0.59 10.6 0.0 2.1 2 0 0 2 2 2 0 EF-hand domain pair PX PF00787.24 OQS03104.1 - 5.3e-06 26.4 0.1 2e-05 24.6 0.1 2.0 1 0 0 1 1 1 1 PX domain zf-RING_2 PF13639.6 OQS03104.1 - 3.5e-05 24.0 12.3 3.5e-05 24.0 12.3 2.2 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.7 OQS03104.1 - 3.9e-05 23.8 7.8 0.00011 22.5 7.8 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 OQS03104.1 - 0.00027 20.7 10.0 0.00027 20.7 10.0 2.2 2 1 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 OQS03104.1 - 0.00028 20.6 3.6 0.00028 20.6 3.6 2.2 2 0 0 2 2 1 1 RING-like zinc finger zf-RING_5 PF14634.6 OQS03104.1 - 0.0015 18.5 12.3 0.0035 17.3 12.3 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 OQS03104.1 - 0.0017 18.3 4.6 0.0044 17.0 4.6 1.8 1 0 0 1 1 1 1 RING-type zinc-finger Mt_ATP-synt_B PF05405.14 OQS03104.1 - 0.013 15.1 0.4 0.59 9.7 0.0 2.4 2 0 0 2 2 2 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) zf-C3HC4 PF00097.25 OQS03104.1 - 0.017 15.0 11.9 0.045 13.6 11.9 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-Nse PF11789.8 OQS03104.1 - 0.05 13.4 3.9 0.2 11.5 3.9 2.1 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-ANAPC11 PF12861.7 OQS03104.1 - 0.23 11.6 3.1 0.58 10.2 3.1 1.7 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.6 OQS03104.1 - 0.87 9.5 9.3 2.5 8.0 9.3 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 OQS03104.1 - 4.7 6.9 9.4 14 5.4 9.4 1.8 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type bZIP_1 PF00170.21 OQS03105.1 - 0.00047 20.2 6.4 0.00047 20.2 6.4 2.2 2 0 0 2 2 2 1 bZIP transcription factor DUF3573 PF12097.8 OQS03105.1 - 0.06 12.2 0.1 0.091 11.6 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) LegC3_N PF18654.1 OQS03105.1 - 0.94 8.7 9.1 1.8 7.7 9.1 1.4 1 0 0 1 1 1 0 LegC3 N-terminal coiled-coil domain Ank_4 PF13637.6 OQS03106.1 - 5.4e-12 46.0 0.2 9.2e-07 29.3 0.1 4.1 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 OQS03106.1 - 4.9e-06 27.0 1.1 0.0041 17.7 0.1 3.4 1 1 3 4 4 4 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OQS03106.1 - 8e-06 26.0 0.7 0.0026 18.0 0.0 4.1 3 2 1 4 4 4 1 Ankyrin repeats (many copies) Pkinase PF00069.25 OQS03106.1 - 6.9e-05 22.3 0.7 0.061 12.7 0.0 2.8 2 1 1 3 3 3 2 Protein kinase domain Ank PF00023.30 OQS03106.1 - 0.00083 19.7 0.4 1.1 9.8 0.0 4.4 4 0 0 4 4 4 1 Ankyrin repeat Ank_3 PF13606.6 OQS03106.1 - 0.0045 17.4 0.0 2 9.2 0.0 4.2 4 0 0 4 4 4 1 Ankyrin repeat Pkinase_Tyr PF07714.17 OQS03106.1 - 0.009 15.3 0.1 0.49 9.6 0.0 2.9 2 1 1 3 3 3 1 Protein tyrosine kinase A2L_zn_ribbon PF08792.10 OQS03106.1 - 0.016 14.9 1.2 0.041 13.6 1.2 1.8 1 0 0 1 1 1 0 A2L zinc ribbon domain IQ PF00612.27 OQS03107.1 - 2.4e-15 54.8 53.1 0.0024 17.5 2.0 8.2 8 0 0 8 8 8 7 IQ calmodulin-binding motif Glyco_transf_41 PF13844.6 OQS03107.1 - 0.00037 19.1 0.9 0.00065 18.3 0.0 1.8 2 0 0 2 2 2 1 Glycosyl transferase family 41 UPF0203 PF05254.12 OQS03107.1 - 3 8.2 5.8 1.6 9.0 0.1 3.1 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0203) Glyco_hydro_31 PF01055.26 OQS03108.1 - 1.2e-136 456.4 6.5 2.2e-136 455.6 6.5 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 B56 PF01603.20 OQS03108.1 - 7.3e-93 311.8 0.4 1e-92 311.3 0.4 1.2 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) Gal_mutarotas_2 PF13802.6 OQS03108.1 - 3.9e-20 72.0 1.0 2.4e-19 69.4 0.2 2.7 2 0 0 2 2 2 1 Galactose mutarotase-like PH PF00169.29 OQS03108.1 - 4.8e-20 72.0 0.0 1.4e-19 70.5 0.0 1.9 1 0 0 1 1 1 1 PH domain ZinT PF09223.11 OQS03108.1 - 0.015 15.2 0.1 0.032 14.1 0.1 1.5 1 0 0 1 1 1 0 ZinT (YodA) periplasmic lipocalin-like zinc-recruitment DUF5110 PF17137.4 OQS03108.1 - 0.029 14.6 0.1 0.073 13.4 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF5110) PH_11 PF15413.6 OQS03108.1 - 0.12 12.8 0.6 0.42 11.0 0.6 2.0 1 1 0 1 1 1 0 Pleckstrin homology domain Aa_trans PF01490.18 OQS03109.1 - 9.9e-43 146.4 16.2 1.3e-42 146.0 16.2 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DUF1422 PF07226.11 OQS03109.1 - 0.36 10.9 10.2 0.6 10.1 3.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1422) PARG_cat PF05028.14 OQS03110.1 - 1.8e-102 343.1 0.0 2.4e-102 342.7 0.0 1.1 1 0 0 1 1 1 1 Poly (ADP-ribose) glycohydrolase (PARG) Ribosomal_L3 PF00297.22 OQS03111.1 - 8.5e-19 67.8 0.8 1.8e-16 60.1 0.6 2.1 1 1 1 2 2 2 2 Ribosomal protein L3 Peptidase_C12 PF01088.21 OQS03112.1 - 2.9e-59 200.4 0.0 3.2e-58 196.9 0.0 1.9 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 Pkinase_Tyr PF07714.17 OQS03113.1 - 4e-28 98.4 0.0 5.8e-28 97.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Ank_4 PF13637.6 OQS03113.1 - 3.9e-25 87.9 0.1 7.2e-09 36.0 0.0 3.3 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Pkinase PF00069.25 OQS03113.1 - 4e-22 78.8 0.0 1.3e-21 77.2 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Ank_2 PF12796.7 OQS03113.1 - 4.9e-22 78.3 0.5 6.7e-14 52.2 0.0 2.5 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OQS03113.1 - 1.4e-16 60.3 0.0 1.8e-10 40.8 0.0 2.9 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 OQS03113.1 - 3.9e-16 58.7 0.1 8.8e-06 25.9 0.0 4.5 4 0 0 4 4 4 3 Ankyrin repeat Ank_3 PF13606.6 OQS03113.1 - 3.4e-14 51.5 0.1 7.4e-05 22.9 0.0 3.8 3 0 0 3 3 3 3 Ankyrin repeat RIO1 PF01163.22 OQS03113.1 - 0.031 13.9 0.0 0.055 13.1 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Band_7 PF01145.25 OQS03114.1 - 6.8e-13 49.0 0.2 6.8e-13 49.0 0.2 2.6 1 1 1 2 2 2 1 SPFH domain / Band 7 family Amidase02_C PF12123.8 OQS03114.1 - 0.17 11.6 0.0 4.7 7.0 0.0 2.6 2 0 0 2 2 2 0 N-acetylmuramoyl-l-alanine amidase Acyltransferase PF01553.21 OQS03115.1 - 4e-15 55.6 0.0 6.8e-15 54.9 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase Penicillinase_R PF03965.16 OQS03115.1 - 0.0014 19.0 0.3 0.0039 17.5 0.3 1.7 1 0 0 1 1 1 1 Penicillinase repressor DivIC PF04977.15 OQS03115.1 - 0.15 11.8 1.4 17 5.2 0.3 3.0 2 0 0 2 2 2 0 Septum formation initiator DUF995 PF06191.12 OQS03116.1 - 0.06 13.0 2.4 0.11 12.1 1.4 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF995) Ribosom_S12_S23 PF00164.25 OQS03118.1 - 0.036 13.7 0.0 0.049 13.3 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein S12/S23 TPR_17 PF13431.6 OQS03120.1 - 1.8e-17 62.3 7.9 0.00028 21.0 0.0 7.8 6 2 1 7 7 7 4 Tetratricopeptide repeat TPR_14 PF13428.6 OQS03120.1 - 1.1e-10 41.4 5.7 0.9 10.5 0.0 7.8 5 3 4 9 9 9 2 Tetratricopeptide repeat TPR_1 PF00515.28 OQS03120.1 - 2.6e-08 33.3 17.0 0.37 10.7 0.0 7.9 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_12 PF13424.6 OQS03120.1 - 1.7e-07 31.4 9.5 1.2 9.5 0.1 6.1 3 1 4 7 7 7 3 Tetratricopeptide repeat TPR_19 PF14559.6 OQS03120.1 - 1.9e-07 31.5 12.1 0.13 12.7 0.2 5.8 5 1 3 8 8 8 4 Tetratricopeptide repeat TPR_8 PF13181.6 OQS03120.1 - 3.2e-06 26.9 16.5 0.17 12.1 0.0 8.1 9 0 0 9 9 9 2 Tetratricopeptide repeat TPR_2 PF07719.17 OQS03120.1 - 1e-05 25.3 23.9 0.59 10.4 0.1 8.3 8 1 1 9 9 8 2 Tetratricopeptide repeat TPR_16 PF13432.6 OQS03120.1 - 0.00037 21.1 14.7 0.33 11.6 0.3 5.5 6 1 1 7 7 7 2 Tetratricopeptide repeat TPR_7 PF13176.6 OQS03120.1 - 0.0044 16.9 6.2 24 5.3 0.0 6.1 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_6 PF13174.6 OQS03120.1 - 0.0065 17.0 5.7 0.43 11.3 0.1 5.2 6 1 0 6 6 4 1 Tetratricopeptide repeat TPR_9 PF13371.6 OQS03120.1 - 0.035 14.2 0.6 4.7 7.4 0.0 3.9 4 1 1 5 5 5 0 Tetratricopeptide repeat Sec16_C PF12931.7 OQS03120.1 - 0.051 13.2 0.7 5.8 6.5 0.0 2.4 2 0 0 2 2 2 0 Sec23-binding domain of Sec16 TPR_11 PF13414.6 OQS03120.1 - 0.052 13.2 8.8 3.7 7.3 0.0 4.8 6 0 0 6 6 6 0 TPR repeat TPR_10 PF13374.6 OQS03120.1 - 6.2 6.8 15.3 22 5.1 0.0 6.1 7 0 0 7 7 7 0 Tetratricopeptide repeat MFS_2 PF13347.6 OQS03121.1 - 1.5e-07 30.4 7.6 1.5e-07 30.4 7.6 2.8 3 0 0 3 3 3 2 MFS/sugar transport protein Ank_4 PF13637.6 OQS03122.1 - 5.2e-13 49.2 0.1 6e-05 23.5 0.0 3.1 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 OQS03122.1 - 7.2e-12 45.7 0.6 8.7e-08 32.7 0.1 2.9 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OQS03122.1 - 8.8e-09 35.5 0.1 0.068 13.5 0.1 4.0 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQS03122.1 - 1.2e-06 28.4 0.0 0.65 10.7 0.0 4.9 5 0 0 5 5 5 1 Ankyrin repeat SNF2_N PF00176.23 OQS03123.1 - 6.3e-79 265.2 0.0 9.6e-79 264.6 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 OQS03123.1 - 1.2e-19 70.7 0.0 1e-18 67.7 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Dynamin_N PF00350.23 OQS03123.1 - 1e-11 45.2 0.0 1.8e-10 41.1 0.0 2.9 2 1 0 2 2 2 1 Dynamin family zf-C3HC4_3 PF13920.6 OQS03123.1 - 4.5e-09 36.0 9.8 8.1e-09 35.2 9.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) ResIII PF04851.15 OQS03123.1 - 3.8e-08 33.5 0.0 1e-07 32.1 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Prok-RING_4 PF14447.6 OQS03123.1 - 5.2e-08 32.6 7.3 1.1e-07 31.5 7.3 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 OQS03123.1 - 1.7e-07 30.9 7.9 3.8e-07 29.8 7.9 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 OQS03123.1 - 2e-07 30.8 6.7 4.1e-07 29.8 6.7 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OQS03123.1 - 1.1e-06 28.4 7.5 2.2e-06 27.5 7.5 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 OQS03123.1 - 5.8e-06 26.5 6.7 1.2e-05 25.5 6.7 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 OQS03123.1 - 7.6e-06 25.9 2.7 7.6e-06 25.9 2.7 1.8 1 1 0 1 1 1 1 RING-type zinc-finger DEAD PF00270.29 OQS03123.1 - 9.8e-06 25.4 0.0 3.4e-05 23.7 0.0 1.9 2 0 0 2 2 1 1 DEAD/DEAH box helicase MMR_HSR1 PF01926.23 OQS03123.1 - 2.2e-05 24.5 0.0 0.0001 22.4 0.0 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase ERCC3_RAD25_C PF16203.5 OQS03123.1 - 0.011 14.9 0.0 0.024 13.8 0.0 1.5 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase DEAD_2 PF06733.15 OQS03123.1 - 0.031 13.9 0.0 0.083 12.5 0.0 1.6 1 0 0 1 1 1 0 DEAD_2 AAA_16 PF13191.6 OQS03123.1 - 0.064 13.6 0.0 0.55 10.6 0.0 2.6 3 0 0 3 3 2 0 AAA ATPase domain DUF5600 PF18150.1 OQS03123.1 - 0.074 13.6 0.1 1.6 9.3 0.0 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF5600) Roc PF08477.13 OQS03123.1 - 0.1 12.8 0.0 4.1 7.6 0.0 3.1 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase zf-C3HC4_4 PF15227.6 OQS03123.1 - 0.27 11.4 10.4 0.47 10.7 8.8 2.2 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-RING_10 PF16685.5 OQS03123.1 - 0.36 11.0 8.9 0.81 9.9 8.9 1.6 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-RING_4 PF14570.6 OQS03123.1 - 0.69 9.7 7.6 1.6 8.6 7.6 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-rbx1 PF12678.7 OQS03123.1 - 1.3 9.4 4.6 3.1 8.2 4.6 1.7 1 0 0 1 1 1 0 RING-H2 zinc finger domain TackOD1 PF18551.1 OQS03123.1 - 1.5 8.4 5.5 0.38 10.4 1.1 2.1 1 1 1 2 2 2 0 Thaumarchaeal output domain 1 Abhydrolase_2 PF02230.16 OQS03124.1 - 1.7e-86 289.5 0.2 1.7e-47 162.1 0.0 2.0 1 1 1 2 2 2 2 Phospholipase/Carboxylesterase Hydrolase_4 PF12146.8 OQS03124.1 - 3.6e-11 42.8 7.6 1.9e-05 24.0 0.0 5.0 4 1 1 5 5 5 3 Serine aminopeptidase, S33 FSH1 PF03959.13 OQS03124.1 - 1.3e-09 38.1 0.0 1.1e-05 25.3 0.0 2.7 2 2 0 2 2 2 2 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.7 OQS03124.1 - 3.9e-07 30.9 0.8 0.022 15.3 2.3 2.6 1 1 1 2 2 2 2 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 OQS03124.1 - 9.2e-06 25.3 1.8 0.00045 19.7 0.0 3.8 4 1 1 5 5 5 1 Prolyl oligopeptidase family Abhydrolase_3 PF07859.13 OQS03124.1 - 5e-05 23.2 0.1 1.6 8.5 0.0 3.2 2 1 1 3 3 3 2 alpha/beta hydrolase fold DUF2974 PF11187.8 OQS03124.1 - 0.00029 20.5 0.0 0.24 10.9 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF2974) DLH PF01738.18 OQS03124.1 - 0.00078 19.1 0.0 0.0017 18.0 0.0 1.5 1 0 0 1 1 1 1 Dienelactone hydrolase family Cutinase PF01083.22 OQS03124.1 - 0.0011 19.0 0.1 0.94 9.4 0.0 2.2 2 0 0 2 2 2 2 Cutinase Abhydrolase_1 PF00561.20 OQS03124.1 - 0.0071 16.0 8.7 0.74 9.4 0.2 4.3 3 2 1 4 4 4 1 alpha/beta hydrolase fold Esterase PF00756.20 OQS03124.1 - 0.016 14.9 0.1 5.5 6.6 0.0 2.6 2 1 0 2 2 2 0 Putative esterase Esterase_phd PF10503.9 OQS03124.1 - 0.02 14.4 0.1 8.1 5.9 0.0 3.2 1 1 2 3 3 3 0 Esterase PHB depolymerase Lipase_3 PF01764.25 OQS03124.1 - 0.021 14.7 0.0 5 7.0 0.0 2.3 2 0 0 2 2 2 0 Lipase (class 3) AXE1 PF05448.12 OQS03124.1 - 0.026 13.2 0.0 3.6 6.2 0.0 2.3 2 0 0 2 2 2 0 Acetyl xylan esterase (AXE1) Methyltransf_4 PF02390.17 OQS03125.1 - 4.5e-41 140.2 0.0 5.4e-41 139.9 0.0 1.0 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_25 PF13649.6 OQS03125.1 - 7.6e-07 29.8 0.0 1.6e-06 28.8 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OQS03125.1 - 7.9e-07 29.0 0.0 1.4e-06 28.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OQS03125.1 - 0.00013 22.7 0.0 0.00027 21.6 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OQS03125.1 - 0.0056 16.5 0.0 0.012 15.5 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OQS03125.1 - 0.01 16.5 0.0 0.022 15.4 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain tRNA_U5-meth_tr PF05958.11 OQS03125.1 - 0.012 14.6 0.0 0.022 13.8 0.0 1.4 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase Methyltransf_18 PF12847.7 OQS03125.1 - 0.022 14.7 0.0 0.038 13.9 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain PCMT PF01135.19 OQS03125.1 - 0.042 13.6 0.0 0.15 11.8 0.0 1.7 2 0 0 2 2 2 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MTS PF05175.14 OQS03125.1 - 0.06 12.9 0.0 0.12 11.9 0.0 1.5 2 0 0 2 2 2 0 Methyltransferase small domain Bap31 PF05529.12 OQS03126.1 - 1.2e-08 34.9 0.2 1.4e-08 34.7 0.2 1.0 1 0 0 1 1 1 1 Bap31/Bap29 transmembrane region DUF485 PF04341.12 OQS03126.1 - 0.11 12.5 3.9 0.6 10.1 0.1 2.3 2 1 0 2 2 2 0 Protein of unknown function, DUF485 NAC PF01849.18 OQS03127.1 - 2.5e-21 75.4 0.4 5.2e-21 74.4 0.4 1.6 1 0 0 1 1 1 1 NAC domain Ribosomal_60s PF00428.19 OQS03127.1 - 0.038 14.6 12.1 0.038 14.6 12.1 2.0 1 1 1 2 2 2 0 60s Acidic ribosomal protein FlxA PF14282.6 OQS03127.1 - 0.044 13.8 2.0 0.044 13.8 2.0 2.0 2 0 0 2 2 2 0 FlxA-like protein PGA2 PF07543.12 OQS03127.1 - 0.28 11.2 7.4 1.5 8.8 0.8 2.1 2 0 0 2 2 2 0 Protein trafficking PGA2 HSP70 PF00012.20 OQS03128.1 - 2.8e-264 877.9 10.5 3.3e-264 877.7 10.5 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 OQS03128.1 - 1.6e-14 53.4 7.9 2.7e-12 46.2 0.2 3.7 3 1 0 3 3 3 2 MreB/Mbl protein FGGY_C PF02782.16 OQS03128.1 - 0.0021 17.8 0.1 0.011 15.5 0.0 2.1 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain FtsA PF14450.6 OQS03128.1 - 0.0023 18.3 7.0 0.81 10.1 0.0 4.0 3 3 0 3 3 3 2 Cell division protein FtsA DMRL_synthase PF00885.19 OQS03128.1 - 0.0081 16.0 0.5 0.027 14.3 0.0 2.1 2 0 0 2 2 2 1 6,7-dimethyl-8-ribityllumazine synthase Ribosomal_S20p PF01649.18 OQS03128.1 - 1.9 9.2 4.9 3 8.6 3.3 2.2 1 1 1 2 2 2 0 Ribosomal protein S20 BT1 PF03092.16 OQS03129.1 - 1.6e-12 46.4 9.8 1.1e-10 40.4 1.6 3.1 3 0 0 3 3 3 3 BT1 family PUCC PF03209.15 OQS03129.1 - 0.00032 19.8 0.6 0.00032 19.8 0.6 2.0 2 0 0 2 2 2 1 PUCC protein SieB PF14163.6 OQS03129.1 - 0.057 12.9 1.3 0.25 10.8 0.0 2.6 2 1 1 3 3 3 0 Super-infection exclusion protein B HypA PF01155.19 OQS03130.1 - 0.28 11.2 5.9 0.4 10.7 5.9 1.4 1 1 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA TIM21 PF08294.11 OQS03131.1 - 7.2e-13 48.6 0.0 9.6e-13 48.2 0.0 1.1 1 0 0 1 1 1 1 TIM21 DUF5353 PF17304.2 OQS03131.1 - 0.11 12.2 0.0 0.23 11.2 0.0 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5353) Tox-SHH PF15652.6 OQS03132.1 - 0.093 13.7 0.7 0.26 12.3 0.7 1.7 1 0 0 1 1 1 0 HNH/Endo VII superfamily toxin with a SHH signature CALM_bind PF16025.5 OQS03132.1 - 7.6 7.1 7.3 16 6.1 7.3 1.6 1 1 0 1 1 1 0 Calcium-dependent calmodulin binding EMP24_GP25L PF01105.24 OQS03133.1 - 2.5e-26 92.7 0.1 3.6e-26 92.2 0.1 1.2 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Uteroglobin PF01099.17 OQS03133.1 - 0.19 12.1 0.5 7.2 7.0 0.0 2.8 3 1 0 3 3 3 0 Uteroglobin family BUD22 PF09073.10 OQS03134.1 - 1.4e-14 54.3 30.9 5.2e-08 32.7 12.8 3.2 2 1 0 3 3 3 3 BUD22 MFS_1 PF07690.16 OQS03135.1 - 3.4e-32 111.7 36.5 3.4e-32 111.7 36.5 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily OATP PF03137.20 OQS03135.1 - 3.9e-21 75.0 20.6 1.2e-15 56.9 11.2 4.3 2 1 2 4 4 4 2 Organic Anion Transporter Polypeptide (OATP) family Sugar_tr PF00083.24 OQS03135.1 - 1.5e-07 30.6 27.9 7.5e-06 25.1 27.9 2.8 1 1 0 1 1 1 1 Sugar (and other) transporter dsrm PF00035.26 OQS03136.1 - 2.3e-16 60.2 0.1 1.4e-06 28.9 0.0 3.0 2 0 0 2 2 2 2 Double-stranded RNA binding motif TPR_1 PF00515.28 OQS03136.1 - 1.6e-05 24.5 0.3 1.6e-05 24.5 0.3 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.17 OQS03136.1 - 0.00011 22.1 0.3 0.00011 22.1 0.3 2.8 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_9 PF13371.6 OQS03136.1 - 0.0004 20.5 0.2 0.001 19.1 0.2 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat Dicer_dimer PF03368.14 OQS03136.1 - 0.003 17.7 0.1 0.12 12.6 0.0 2.9 2 0 0 2 2 2 1 Dicer dimerisation domain TPR_14 PF13428.6 OQS03136.1 - 0.0069 17.1 0.2 0.0069 17.1 0.2 3.1 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.6 OQS03136.1 - 0.025 15.1 2.7 0.036 14.6 0.3 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat NEXCaM_BD PF16644.5 OQS03136.1 - 1.4 9.2 5.2 3.3 8.0 0.7 2.7 3 0 0 3 3 3 0 Regulatory region of Na+/H+ exchanger NHE binds to calmodulin TipAS PF07739.13 OQS03136.1 - 2.5 8.7 10.8 0.11 13.0 1.2 3.4 2 1 1 3 3 3 0 TipAS antibiotic-recognition domain Adaptin_N PF01602.20 OQS03137.1 - 1.1e-118 397.1 5.6 1.5e-118 396.7 5.6 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 OQS03137.1 - 2.8e-23 82.8 6.9 1.2e-22 80.7 1.4 3.1 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 AP3B1_C PF14796.6 OQS03137.1 - 4.8e-15 56.1 1.4 8.6e-15 55.3 0.2 2.0 2 0 0 2 2 1 1 Clathrin-adaptor complex-3 beta-1 subunit C-terminal HEAT_2 PF13646.6 OQS03137.1 - 1.7e-09 37.9 4.0 5.5e-07 29.9 0.6 4.1 2 1 2 4 4 4 1 HEAT repeats SDA1 PF05285.12 OQS03137.1 - 0.00074 19.1 27.1 0.0012 18.3 27.1 1.2 1 0 0 1 1 1 1 SDA1 HEAT PF02985.22 OQS03137.1 - 0.0029 17.7 12.5 0.13 12.6 0.0 5.6 6 1 1 7 7 7 2 HEAT repeat Nop14 PF04147.12 OQS03137.1 - 0.014 13.7 28.6 0.011 14.1 27.1 1.5 2 0 0 2 2 2 0 Nop14-like family CDC45 PF02724.14 OQS03137.1 - 0.027 12.8 19.6 0.051 11.9 19.6 1.4 1 0 0 1 1 1 0 CDC45-like protein HEAT_EZ PF13513.6 OQS03137.1 - 0.032 14.8 6.7 0.064 13.8 0.1 4.5 4 1 1 5 5 4 0 HEAT-like repeat Mpp10 PF04006.12 OQS03137.1 - 0.14 10.5 26.9 0.23 9.9 26.9 1.2 1 0 0 1 1 1 0 Mpp10 protein SAPS PF04499.15 OQS03137.1 - 0.38 9.5 11.5 0.12 11.2 8.2 1.8 2 0 0 2 2 2 0 SIT4 phosphatase-associated protein Hid1 PF12722.7 OQS03137.1 - 0.38 8.8 9.8 0.59 8.2 9.8 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein RTP1_C1 PF10363.9 OQS03137.1 - 0.51 10.5 4.4 38 4.5 0.2 4.0 4 1 0 4 4 3 0 Required for nuclear transport of RNA pol II C-terminus 1 YL1 PF05764.13 OQS03137.1 - 1.9 8.6 27.8 0.058 13.5 21.4 1.7 2 0 0 2 2 1 0 YL1 nuclear protein Zip PF02535.22 OQS03137.1 - 3.6 6.7 7.5 6.8 5.8 7.5 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter Roughex PF06020.11 OQS03137.1 - 4.6 6.2 19.7 7.7 5.5 19.7 1.2 1 0 0 1 1 1 0 Drosophila roughex protein PTPRCAP PF15713.5 OQS03137.1 - 5.9 7.2 25.2 0.3 11.4 19.7 1.7 2 0 0 2 2 1 0 Protein tyrosine phosphatase receptor type C-associated DUF1387 PF07139.11 OQS03137.1 - 6.6 6.4 18.5 13 5.3 18.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) DENN PF02141.21 OQS03138.1 - 8.8e-08 32.3 3.1 2.6e-07 30.8 3.1 1.8 1 0 0 1 1 1 1 DENN (AEX-3) domain TPR_19 PF14559.6 OQS03138.1 - 0.065 13.8 2.6 41 4.8 0.0 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF4954 PF16314.5 OQS03139.1 - 9.6e-50 169.4 0.0 1.3e-49 169.0 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4954) WD40 PF00400.32 OQS03141.1 - 2.3e-16 59.8 0.7 4.5e-07 30.5 0.1 5.8 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OQS03141.1 - 7.7e-10 38.9 0.0 0.00036 20.8 0.0 3.4 3 0 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 OQS03141.1 - 0.042 12.5 0.6 0.16 10.6 0.1 2.0 2 1 0 2 2 2 0 Nucleoporin Nup120/160 DUF3648 PF12364.8 OQS03141.1 - 0.12 12.5 0.1 6.8 6.9 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3648) Dus PF01207.17 OQS03142.1 - 1.2e-51 175.7 0.8 3.6e-51 174.1 0.8 1.7 1 1 0 1 1 1 1 Dihydrouridine synthase (Dus) zf-C2H2_jaz PF12171.8 OQS03142.1 - 0.0019 18.5 0.1 0.0054 17.0 0.0 1.9 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding NMO PF03060.15 OQS03142.1 - 0.0024 17.3 0.7 0.78 9.1 0.1 2.6 3 0 0 3 3 3 2 Nitronate monooxygenase Pkinase PF00069.25 OQS03143.1 - 8.1e-67 225.4 0.0 1.1e-66 224.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQS03143.1 - 2.7e-43 148.1 0.0 3.9e-43 147.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase ATG11 PF10377.9 OQS03143.1 - 3.6e-30 104.7 0.0 5.7e-17 62.0 0.0 3.0 3 0 0 3 3 3 2 Autophagy-related protein 11 ABC1 PF03109.16 OQS03143.1 - 0.0021 18.2 0.0 0.0047 17.1 0.0 1.5 1 0 0 1 1 1 1 ABC1 family Pkinase_fungal PF17667.1 OQS03143.1 - 0.02 13.7 0.0 0.032 13.0 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Kdo PF06293.14 OQS03143.1 - 0.02 14.2 0.0 0.034 13.5 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OQS03143.1 - 0.046 13.6 0.0 0.37 10.7 0.0 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family Kinase-like PF14531.6 OQS03143.1 - 0.062 12.6 0.0 0.12 11.7 0.0 1.5 1 1 0 1 1 1 0 Kinase-like YrbL-PhoP_reg PF10707.9 OQS03143.1 - 0.16 11.5 0.0 0.5 9.9 0.0 1.8 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL Stealth_CR2 PF11380.8 OQS03144.1 - 6.5e-70 232.2 0.1 5.5e-35 119.8 0.1 2.8 2 0 0 2 2 2 2 Stealth protein CR2, conserved region 2 PTPlike_phytase PF14566.6 OQS03144.1 - 2.2e-68 229.3 0.7 1.6e-38 132.3 0.0 2.8 3 0 0 3 3 2 2 Inositol hexakisphosphate Stealth_CR3 PF17102.5 OQS03144.1 - 2.6e-18 65.7 11.3 2.7e-09 36.8 3.3 3.1 3 0 0 3 3 3 2 Stealth protein CR3, conserved region 3 Stealth_CR1 PF17101.5 OQS03144.1 - 1.5e-15 56.6 0.0 1e-06 28.4 0.0 2.7 2 0 0 2 2 2 2 Stealth protein CR1, conserved region 1 Stealth_CR4 PF17103.5 OQS03144.1 - 1.3e-13 50.6 0.0 9.9e-07 28.6 0.0 2.7 2 0 0 2 2 2 2 Stealth protein CR4, conserved region 4 FYVE PF01363.21 OQS03144.1 - 2.1e-11 43.8 18.6 2.1e-11 43.8 18.6 2.1 2 0 0 2 2 1 1 FYVE zinc finger zf-RING_2 PF13639.6 OQS03144.1 - 1.6e-10 41.1 9.7 1.6e-10 41.1 9.7 4.1 3 1 1 4 4 4 1 Ring finger domain zf-C3HC4_2 PF13923.6 OQS03144.1 - 7e-07 29.0 10.0 7e-07 29.0 10.0 3.1 3 0 0 3 3 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 OQS03144.1 - 5.4e-06 26.0 7.2 1.6e-05 24.5 7.2 1.9 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4 PF00097.25 OQS03144.1 - 0.0001 22.1 8.2 0.0001 22.1 8.2 4.2 3 1 1 4 4 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 OQS03144.1 - 0.00019 21.7 13.3 0.00019 21.7 13.3 2.5 2 0 0 2 2 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 OQS03144.1 - 0.00026 20.9 6.4 0.00026 20.9 6.4 2.8 2 0 0 2 2 1 1 zinc-RING finger domain DSPc PF00782.20 OQS03144.1 - 0.00087 19.1 0.0 0.0064 16.3 0.0 2.3 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain zf-ANAPC11 PF12861.7 OQS03144.1 - 0.037 14.1 6.4 0.16 12.0 6.4 2.1 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger IQ PF00612.27 OQS03144.1 - 0.1 12.4 0.5 0.33 10.9 0.5 1.9 1 0 0 1 1 1 0 IQ calmodulin-binding motif PROCN PF08083.11 OQS03145.1 - 1.1e-236 785.1 6.2 1.7e-236 784.6 6.2 1.3 1 0 0 1 1 1 1 PROCN (NUC071) domain PRP8_domainIV PF12134.8 OQS03145.1 - 8.4e-127 421.5 0.5 1.4e-126 420.8 0.5 1.4 1 0 0 1 1 1 1 PRP8 domain IV core U6-snRNA_bdg PF10596.9 OQS03145.1 - 5.7e-90 299.4 2.3 1.4e-89 298.1 2.3 1.7 1 0 0 1 1 1 1 U6-snRNA interacting domain of PrP8 PRO8NT PF08082.11 OQS03145.1 - 1.8e-88 294.2 3.4 5e-88 292.8 3.4 1.8 1 0 0 1 1 1 1 PRO8NT (NUC069), PrP8 N-terminal domain U5_2-snRNA_bdg PF10597.9 OQS03145.1 - 8.2e-73 242.8 0.0 1.5e-72 241.9 0.0 1.5 1 0 0 1 1 1 1 U5-snRNA binding site 2 of PrP8 PROCT PF08084.11 OQS03145.1 - 1.1e-51 173.9 0.1 2.7e-51 172.7 0.1 1.7 1 0 0 1 1 1 1 PROCT (NUC072) domain RRM_4 PF10598.9 OQS03145.1 - 5.1e-47 158.2 0.5 1.3e-46 156.8 0.5 1.8 1 0 0 1 1 1 1 RNA recognition motif of the spliceosomal PrP8 JAB PF01398.21 OQS03145.1 - 3.6e-09 36.6 0.0 8.4e-09 35.4 0.0 1.7 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease GIIM PF08388.11 OQS03145.1 - 0.26 11.4 0.0 0.26 11.4 0.0 2.7 3 0 0 3 3 3 0 Group II intron, maturase-specific domain Pkinase PF00069.25 OQS03146.1 - 0.0011 18.4 0.0 0.0019 17.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain TPR_1 PF00515.28 OQS03147.1 - 0.0012 18.5 3.4 0.0037 17.0 0.3 3.0 2 0 0 2 2 2 1 Tetratricopeptide repeat HrpB1_HrpK PF09613.10 OQS03147.1 - 0.014 15.0 0.1 0.11 12.1 0.0 2.2 2 0 0 2 2 2 0 Bacterial type III secretion protein (HrpB1_HrpK) TPR_2 PF07719.17 OQS03147.1 - 0.021 14.9 0.2 0.021 14.9 0.2 4.0 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_12 PF13424.6 OQS03147.1 - 0.027 14.7 2.0 8.9 6.7 2.1 3.0 1 1 2 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 OQS03147.1 - 0.067 14.0 0.1 1.8e+02 3.4 0.0 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat IQ PF00612.27 OQS03147.1 - 0.079 12.8 0.2 0.26 11.2 0.2 2.0 1 0 0 1 1 1 0 IQ calmodulin-binding motif TPR_8 PF13181.6 OQS03147.1 - 0.18 12.1 4.2 3.3 8.2 0.1 4.1 3 0 0 3 3 3 0 Tetratricopeptide repeat ANAPC3 PF12895.7 OQS03147.1 - 4 7.7 7.6 15 5.9 0.7 4.0 3 2 1 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 DUF2721 PF11026.8 OQS03149.1 - 0.009 15.9 0.4 0.009 15.9 0.4 2.8 2 1 1 3 3 3 1 Protein of unknown function (DUF2721) FAD_binding_6 PF00970.24 OQS03150.1 - 9.5e-05 22.7 0.0 0.0043 17.4 0.0 2.5 2 0 0 2 2 2 1 Oxidoreductase FAD-binding domain Globin PF00042.22 OQS03150.1 - 0.00012 22.6 2.6 0.14 12.7 0.2 3.2 2 2 0 2 2 2 2 Globin E1-E2_ATPase PF00122.20 OQS03152.1 - 4.1e-31 107.9 2.8 7.2e-31 107.1 2.8 1.4 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.26 OQS03152.1 - 1e-06 29.2 0.0 6.6e-06 26.6 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase P5-ATPase PF12409.8 OQS03152.1 - 1.2e-06 28.6 2.3 6.2e-06 26.3 0.0 2.5 1 1 1 2 2 2 1 P5-type ATPase cation transporter Cation_ATPase PF13246.6 OQS03152.1 - 6.4e-05 23.0 0.0 0.00013 22.0 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) DUF1295 PF06966.12 OQS03153.1 - 9.9e-64 215.1 3.7 1.3e-63 214.7 3.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) Steroid_dh PF02544.16 OQS03153.1 - 4.8e-10 39.6 7.0 7.8e-10 38.9 2.1 3.0 2 1 0 2 2 2 1 3-oxo-5-alpha-steroid 4-dehydrogenase ICMT PF04140.14 OQS03153.1 - 0.00059 20.2 0.2 0.00059 20.2 0.2 2.2 2 0 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family Pox_A14 PF05767.12 OQS03153.1 - 0.025 14.7 2.0 0.054 13.6 0.1 2.5 3 0 0 3 3 3 0 Poxvirus virion envelope protein A14 PEMT PF04191.13 OQS03153.1 - 0.099 13.0 0.1 0.099 13.0 0.1 3.2 4 0 0 4 4 4 0 Phospholipid methyltransferase Phage_holin_3_6 PF07332.11 OQS03153.1 - 2.8 8.0 11.6 7 6.7 4.0 3.2 3 0 0 3 3 3 0 Putative Actinobacterial Holin-X, holin superfamily III DUF1298 PF06974.13 OQS03154.1 - 1.7e-26 92.9 0.1 2.8e-26 92.2 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1298) WES_acyltransf PF03007.16 OQS03154.1 - 1.6e-12 47.8 0.2 7.2e-08 32.5 0.1 2.2 1 1 1 2 2 2 2 Wax ester synthase-like Acyl-CoA acyltransferase domain Condensation PF00668.20 OQS03154.1 - 1e-06 27.7 0.0 3e-06 26.2 0.0 1.7 1 1 0 1 1 1 1 Condensation domain DUF1295 PF06966.12 OQS03155.1 - 5.7e-58 196.2 4.0 7.2e-58 195.9 4.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) Steroid_dh PF02544.16 OQS03155.1 - 2.1e-06 27.8 0.3 2.2e-05 24.5 0.3 2.2 2 0 0 2 2 2 1 3-oxo-5-alpha-steroid 4-dehydrogenase ICMT PF04140.14 OQS03155.1 - 8.9e-05 22.8 0.1 0.00027 21.3 0.1 1.8 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 OQS03155.1 - 0.00069 20.0 0.4 0.0028 18.0 0.4 2.0 1 0 0 1 1 1 1 Phospholipid methyltransferase Gal11_ABD1 PF18535.1 OQS03155.1 - 0.15 12.2 0.0 0.28 11.3 0.0 1.3 1 0 0 1 1 1 0 Gal11 activator-binding domain (ABD1) Aminotran_1_2 PF00155.21 OQS03156.1 - 2.2e-59 201.5 0.0 2.5e-59 201.3 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 OQS03156.1 - 0.00012 21.1 0.0 0.00018 20.6 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 OQS03156.1 - 0.018 14.4 0.1 0.02 14.2 0.1 1.2 1 0 0 1 1 1 0 Beta-eliminating lyase Flavin_Reduct PF01613.18 OQS03157.1 - 6.7e-18 65.2 0.2 2.3e-15 57.0 0.3 2.1 2 0 0 2 2 2 2 Flavin reductase like domain fn3_4 PF16794.5 OQS03157.1 - 0.056 13.4 0.0 9.8 6.2 0.0 2.3 2 0 0 2 2 2 0 Fibronectin-III type domain Flavin_Reduct PF01613.18 OQS03158.1 - 0.00068 19.7 0.6 0.0008 19.5 0.6 1.1 1 0 0 1 1 1 1 Flavin reductase like domain Ribosomal_S10 PF00338.22 OQS03159.1 - 6.4e-28 96.9 0.0 8e-28 96.5 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e Baculo_PEP_C PF04513.12 OQS03160.1 - 0.048 13.7 0.1 0.048 13.7 0.1 5.3 4 1 1 5 5 5 0 Baculovirus polyhedron envelope protein, PEP, C terminus ApoC-I PF04691.12 OQS03160.1 - 0.17 11.8 4.0 3.3 7.7 0.1 3.9 4 0 0 4 4 4 0 Apolipoprotein C-I (ApoC-1) IL2 PF00715.17 OQS03160.1 - 0.52 10.2 7.6 8.8 6.3 0.1 3.8 3 2 0 4 4 4 0 Interleukin 2 ABC_membrane PF00664.23 OQS03161.1 - 8.3e-63 212.6 6.7 1e-62 212.3 6.7 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region FlgN PF05130.12 OQS03161.1 - 0.014 15.9 1.1 0.03 14.9 1.1 1.4 1 0 0 1 1 1 0 FlgN protein PsbN PF02468.15 OQS03161.1 - 0.18 11.7 0.7 0.51 10.2 0.7 1.7 1 0 0 1 1 1 0 Photosystem II reaction centre N protein (psbN) DUF2053 PF09767.9 OQS03161.1 - 0.2 11.8 5.0 0.072 13.2 1.1 2.1 2 0 0 2 2 2 0 Predicted membrane protein (DUF2053) DUF3099 PF11298.8 OQS03161.1 - 0.36 11.0 1.9 19 5.4 0.2 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3099) ABC_membrane PF00664.23 OQS03162.1 - 2e-57 194.9 10.1 2.4e-57 194.7 10.1 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 OQS03162.1 - 2.3e-13 50.8 0.0 4.3e-13 49.9 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_29 PF13555.6 OQS03162.1 - 0.00063 19.4 0.0 0.0021 17.8 0.0 1.8 2 0 0 2 2 2 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 OQS03162.1 - 0.01 15.8 0.1 0.019 14.9 0.1 1.3 1 0 0 1 1 1 1 RsgA GTPase AAA_16 PF13191.6 OQS03162.1 - 0.011 16.1 0.1 0.028 14.8 0.1 1.6 1 0 0 1 1 1 0 AAA ATPase domain DUF87 PF01935.17 OQS03162.1 - 0.011 15.8 0.1 0.022 14.9 0.1 1.3 1 0 0 1 1 1 0 Helicase HerA, central domain G-alpha PF00503.20 OQS03162.1 - 0.044 12.9 0.0 0.068 12.3 0.0 1.2 1 0 0 1 1 1 0 G-protein alpha subunit AAA_5 PF07728.14 OQS03162.1 - 0.063 13.3 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 OQS03162.1 - 0.086 13.1 0.0 0.17 12.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain APS_kinase PF01583.20 OQS03162.1 - 0.092 12.6 0.0 0.18 11.7 0.0 1.5 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_25 PF13481.6 OQS03162.1 - 0.095 12.3 0.0 0.17 11.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain SRP54 PF00448.22 OQS03162.1 - 0.097 12.3 0.1 0.65 9.6 0.0 2.0 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain Zeta_toxin PF06414.12 OQS03162.1 - 0.1 11.8 0.0 0.18 11.0 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_15 PF13175.6 OQS03162.1 - 0.26 10.9 0.0 0.4 10.3 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain PsbN PF02468.15 OQS03162.1 - 0.86 9.5 3.6 2.5 8.0 3.6 1.7 1 0 0 1 1 1 0 Photosystem II reaction centre N protein (psbN) DUF373 PF04123.13 OQS03162.1 - 3.7 6.9 9.2 1.2 8.6 1.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF373) GRIP PF01465.20 OQS03163.1 - 9.1e-17 60.7 0.6 2.6e-16 59.2 0.6 1.9 1 0 0 1 1 1 1 GRIP domain Spc7 PF08317.11 OQS03163.1 - 1.7e-06 27.2 55.2 1.4e-05 24.1 27.4 20.7 1 1 17 21 21 21 8 Spc7 kinetochore protein ATG16 PF08614.11 OQS03163.1 - 5.3e-05 23.5 31.6 5.3e-05 23.5 31.6 21.9 2 2 17 20 20 20 5 Autophagy protein 16 (ATG16) DUF3450 PF11932.8 OQS03163.1 - 0.0029 16.9 5.3 0.0029 16.9 5.3 26.3 2 1 27 30 30 30 6 Protein of unknown function (DUF3450) Complex1_LYR_2 PF13233.6 OQS03163.1 - 4.6 8.0 13.3 1.1 10.1 1.1 6.1 3 1 0 3 3 3 0 Complex1_LYR-like RCC1 PF00415.18 OQS03164.1 - 3.5e-43 146.0 16.9 3.6e-12 46.7 0.7 7.7 7 1 0 7 7 7 5 Regulator of chromosome condensation (RCC1) repeat PI3_PI4_kinase PF00454.27 OQS03164.1 - 4.2e-32 111.9 0.1 1.5e-29 103.5 0.0 2.7 2 1 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase RCC1_2 PF13540.6 OQS03164.1 - 2.8e-21 74.8 25.0 4.6e-06 26.3 2.3 6.7 6 1 0 6 6 6 4 Regulator of chromosome condensation (RCC1) repeat IQ PF00612.27 OQS03164.1 - 0.00017 21.1 0.0 0.00017 21.1 0.0 4.6 5 0 0 5 5 5 1 IQ calmodulin-binding motif PI3Ka PF00613.20 OQS03164.1 - 0.0022 17.4 0.0 0.0057 16.1 0.0 1.6 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) WW PF00397.26 OQS03164.1 - 0.0037 17.3 2.3 0.055 13.6 0.1 2.7 2 0 0 2 2 2 1 WW domain DUF4135 PF13575.6 OQS03164.1 - 0.1 11.9 0.0 0.16 11.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4135) MreD PF04093.12 OQS03164.1 - 1.1 9.3 5.6 2.1 8.4 5.6 1.4 1 0 0 1 1 1 0 rod shape-determining protein MreD Methyltr_RsmB-F PF01189.17 OQS03166.1 - 1.7e-21 76.8 0.0 1.1e-20 74.1 0.0 2.3 1 1 0 1 1 1 1 16S rRNA methyltransferase RsmB/F Sugar_tr PF00083.24 OQS03168.1 - 1.7e-34 119.5 20.9 4.5e-34 118.1 20.5 1.7 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OQS03168.1 - 1.4e-11 43.9 39.5 2.6e-08 33.2 26.9 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily LSR PF05624.14 OQS03168.1 - 3.5 7.7 5.6 1.8 8.6 0.0 3.4 2 1 1 3 3 3 0 Lipolysis stimulated receptor (LSR) Phage_holin_3_2 PF04550.12 OQS03168.1 - 7.2 7.2 9.8 0.19 12.3 1.2 2.8 2 0 0 2 2 2 0 Phage holin family 2 NTP_transf_2 PF01909.23 OQS03169.1 - 9.1e-10 38.7 0.0 1.9e-09 37.7 0.0 1.6 1 0 0 1 1 1 1 Nucleotidyltransferase domain PAP_assoc PF03828.19 OQS03169.1 - 2e-07 31.1 0.1 4.6e-07 30.0 0.1 1.7 1 0 0 1 1 1 1 Cid1 family poly A polymerase DNA_pol_B_palm PF14792.6 OQS03169.1 - 0.02 15.1 0.0 0.04 14.1 0.0 1.4 1 0 0 1 1 1 0 DNA polymerase beta palm tRNA_NucTransf2 PF09249.11 OQS03169.1 - 0.021 15.1 0.0 0.27 11.5 0.0 2.5 3 0 0 3 3 3 0 tRNA nucleotidyltransferase, second domain Polbeta PF18765.1 OQS03169.1 - 0.098 12.8 0.0 0.21 11.7 0.0 1.5 1 0 0 1 1 1 0 Polymerase beta, Nucleotidyltransferase Methyltransf_5 PF01795.19 OQS03170.1 - 0.026 14.0 0.1 0.036 13.6 0.1 1.2 1 0 0 1 1 1 0 MraW methylase family UPF0060 PF02694.15 OQS03171.1 - 7.8e-29 100.1 11.4 8.8e-29 99.9 11.4 1.0 1 0 0 1 1 1 1 Uncharacterised BCR, YnfA/UPF0060 family EamA PF00892.20 OQS03171.1 - 0.00031 20.9 11.0 0.00032 20.9 4.9 2.0 1 1 1 2 2 2 1 EamA-like transporter family DUF1358 PF07096.11 OQS03171.1 - 0.0055 16.7 1.4 0.0075 16.2 1.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1358) Multi_Drug_Res PF00893.19 OQS03171.1 - 0.19 12.4 12.0 0.088 13.5 8.9 1.8 1 1 1 2 2 2 0 Small Multidrug Resistance protein DUF1978 PF09321.10 OQS03172.1 - 0.03 13.7 0.1 0.031 13.6 0.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF1978) WW PF00397.26 OQS03172.1 - 0.051 13.7 1.8 0.051 13.7 1.8 1.7 2 0 0 2 2 2 0 WW domain WW PF00397.26 OQS03173.1 - 0.00065 19.7 1.8 0.0012 18.9 1.8 1.4 1 0 0 1 1 1 1 WW domain CEBP_ZZ PF16366.5 OQS03173.1 - 0.048 13.9 5.1 0.11 12.7 5.1 1.6 1 0 0 1 1 1 0 Cytoplasmic polyadenylation element-binding protein ZZ domain FERM_f0 PF16511.5 OQS03173.1 - 0.096 13.0 0.1 0.29 11.5 0.1 1.8 1 0 0 1 1 1 0 N-terminal or F0 domain of Talin-head FERM Siva PF05458.12 OQS03173.1 - 0.11 12.2 3.5 0.21 11.3 2.2 2.0 2 0 0 2 2 2 0 Cd27 binding protein (Siva) DUF4201 PF13870.6 OQS03175.1 - 0.00073 19.3 21.3 0.00073 19.3 21.3 5.2 2 2 1 4 4 4 1 Domain of unknown function (DUF4201) LBP_BPI_CETP PF01273.25 OQS03175.1 - 0.0048 16.5 0.2 3.6 7.2 0.0 2.8 2 0 0 2 2 2 2 LBP / BPI / CETP family, N-terminal domain TMF_DNA_bd PF12329.8 OQS03175.1 - 0.011 15.7 7.3 0.011 15.7 7.3 7.8 5 2 2 7 7 7 0 TATA element modulatory factor 1 DNA binding LRR_6 PF13516.6 OQS03175.1 - 0.025 14.6 0.5 0.53 10.5 0.0 2.9 2 0 0 2 2 2 0 Leucine Rich repeat Transglut_N PF00868.20 OQS03175.1 - 0.14 12.5 2.3 0.33 11.3 0.5 2.7 2 1 0 2 2 2 0 Transglutaminase family Flu_NS2 PF00601.19 OQS03175.1 - 1.1 9.6 13.7 2.5 8.4 2.6 4.1 2 2 1 3 3 3 0 Influenza non-structural protein (NS2) Fez1 PF06818.15 OQS03175.1 - 2.3 8.6 79.0 0.76 10.2 9.4 5.0 2 1 2 4 4 4 0 Fez1 Nramp PF01566.18 OQS03177.1 - 4.5e-115 384.4 11.3 4.5e-115 384.4 11.3 3.2 4 0 0 4 4 4 1 Natural resistance-associated macrophage protein Sugar_tr PF00083.24 OQS03177.1 - 5.1e-48 164.0 21.8 1.9e-47 162.2 21.8 2.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OQS03177.1 - 4.3e-35 121.3 75.9 2.2e-33 115.7 15.5 4.2 2 1 1 3 3 3 2 Major Facilitator Superfamily Baculo_PEP_N PF04512.12 OQS03177.1 - 0.19 12.0 0.1 2.2 8.6 0.0 2.6 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, N terminus ParA PF10609.9 OQS03179.1 - 3.7e-93 311.5 1.0 6.2e-83 278.0 1.5 2.3 2 0 0 2 2 2 2 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 OQS03179.1 - 2.3e-11 43.8 0.0 1.3e-10 41.4 0.0 2.2 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 OQS03179.1 - 4.9e-08 33.1 0.2 4.6e-07 29.9 0.2 2.3 1 1 0 1 1 1 1 AAA domain ArsA_ATPase PF02374.15 OQS03179.1 - 1.1e-06 28.0 3.5 2.6e-06 26.9 0.8 2.2 1 1 0 2 2 2 1 Anion-transporting ATPase MipZ PF09140.11 OQS03179.1 - 3.9e-06 26.3 0.0 1.1e-05 24.9 0.0 1.7 1 1 0 1 1 1 1 ATPase MipZ Fer4_NifH PF00142.18 OQS03179.1 - 0.00072 19.1 0.7 0.02 14.4 0.1 2.5 3 0 0 3 3 3 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family CBP_BcsQ PF06564.12 OQS03179.1 - 0.013 15.0 0.1 0.24 10.8 0.1 2.8 2 1 0 2 2 2 0 Cellulose biosynthesis protein BcsQ AAA_25 PF13481.6 OQS03179.1 - 0.014 15.0 0.1 0.027 14.0 0.1 1.4 1 0 0 1 1 1 0 AAA domain PcrB PF01884.17 OQS03179.1 - 0.016 14.7 0.1 0.032 13.7 0.1 1.4 1 0 0 1 1 1 0 PcrB family MeaB PF03308.16 OQS03179.1 - 0.017 14.1 0.2 0.028 13.4 0.2 1.2 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB NB-ARC PF00931.22 OQS03179.1 - 0.019 14.2 0.2 0.036 13.2 0.2 1.4 1 0 0 1 1 1 0 NB-ARC domain APS_kinase PF01583.20 OQS03179.1 - 0.04 13.8 0.1 0.074 12.9 0.1 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase RsgA_GTPase PF03193.16 OQS03179.1 - 0.52 10.2 2.0 0.53 10.2 0.2 1.8 2 0 0 2 2 2 0 RsgA GTPase Complex1_LYR PF05347.15 OQS03180.1 - 7.7e-06 25.9 0.0 1.5e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 Complex 1 protein (LYR family) ABC_tran PF00005.27 OQS03181.1 - 1.1e-43 149.0 13.8 3.7e-23 82.6 0.0 4.5 4 1 0 4 4 2 2 ABC transporter 5_3_exonuc_N PF02739.16 OQS03181.1 - 6.4e-33 113.9 1.8 1.2e-31 109.8 0.1 2.8 3 0 0 3 3 2 1 5'-3' exonuclease, N-terminal resolvase-like domain AAA_21 PF13304.6 OQS03181.1 - 4.3e-16 59.6 4.7 0.00027 20.8 0.1 4.9 4 1 0 5 5 5 4 AAA domain, putative AbiEii toxin, Type IV TA system 5_3_exonuc PF01367.20 OQS03181.1 - 2.5e-13 50.5 0.0 2.5e-13 50.5 0.0 3.7 4 1 0 4 4 1 1 5'-3' exonuclease, C-terminal SAM fold AAA_29 PF13555.6 OQS03181.1 - 1.4e-08 34.3 0.1 0.003 17.2 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain ABC_tran_Xtn PF12848.7 OQS03181.1 - 5.7e-07 29.5 9.5 5.7e-07 29.5 9.5 6.3 4 2 4 8 8 2 1 ABC transporter AAA_16 PF13191.6 OQS03181.1 - 6.2e-07 30.0 0.1 0.073 13.4 0.0 4.0 3 0 0 3 3 3 2 AAA ATPase domain AAA_22 PF13401.6 OQS03181.1 - 1.5e-06 28.5 0.4 0.0063 16.8 0.0 3.5 3 0 0 3 3 3 2 AAA domain RsgA_GTPase PF03193.16 OQS03181.1 - 5.1e-06 26.5 0.0 0.0065 16.4 0.0 3.1 2 0 0 2 2 2 1 RsgA GTPase SMC_N PF02463.19 OQS03181.1 - 8e-06 25.4 15.8 0.06 12.8 0.0 5.2 4 2 1 5 5 5 3 RecF/RecN/SMC N terminal domain AAA PF00004.29 OQS03181.1 - 1.5e-05 25.4 0.0 0.48 10.9 0.0 3.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 OQS03181.1 - 0.00013 21.9 2.3 0.38 10.6 0.0 3.0 3 0 0 3 3 3 2 NACHT domain MMR_HSR1 PF01926.23 OQS03181.1 - 0.00027 21.0 0.2 0.057 13.5 0.1 4.1 3 0 0 3 3 3 1 50S ribosome-binding GTPase RNA_helicase PF00910.22 OQS03181.1 - 0.0012 19.2 0.0 0.65 10.4 0.0 2.8 2 0 0 2 2 2 1 RNA helicase AAA_14 PF13173.6 OQS03181.1 - 0.0021 18.1 0.0 5.8 7.0 0.0 3.5 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.6 OQS03181.1 - 0.0021 17.8 3.5 0.58 9.8 0.0 3.7 3 1 1 4 4 4 2 AAA domain AAA_23 PF13476.6 OQS03181.1 - 0.0029 18.1 5.7 0.013 16.0 1.0 7.0 5 2 0 5 5 4 2 AAA domain AAA_33 PF13671.6 OQS03181.1 - 0.0032 17.6 0.0 4.3 7.5 0.0 3.0 2 0 0 2 2 2 1 AAA domain NTPase_1 PF03266.15 OQS03181.1 - 0.0033 17.3 0.0 1.3 8.9 0.0 2.8 2 0 0 2 2 2 1 NTPase AAA_28 PF13521.6 OQS03181.1 - 0.0049 17.1 3.5 2.9 8.1 0.0 4.4 4 0 0 4 4 4 1 AAA domain Roc PF08477.13 OQS03181.1 - 0.0052 17.0 0.4 2.6 8.3 0.0 3.4 3 1 1 4 4 2 1 Ras of Complex, Roc, domain of DAPkinase AAA_7 PF12775.7 OQS03181.1 - 0.0068 15.9 0.0 1.4 8.4 0.0 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_15 PF13175.6 OQS03181.1 - 0.038 13.7 0.0 0.038 13.7 0.0 4.8 2 1 1 3 3 2 0 AAA ATPase domain IstB_IS21 PF01695.17 OQS03181.1 - 0.051 13.3 0.1 4.3 7.0 0.0 2.7 2 0 0 2 2 2 0 IstB-like ATP binding protein RuvB_N PF05496.12 OQS03181.1 - 0.057 13.2 0.1 6.6 6.5 0.0 2.4 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 OQS03181.1 - 0.2 12.2 7.4 0.85 10.2 0.1 4.9 4 1 0 4 4 3 0 AAA domain AAA_5 PF07728.14 OQS03181.1 - 0.22 11.5 4.1 2.3 8.2 0.0 3.4 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) cobW PF02492.19 OQS03181.1 - 0.33 10.5 4.6 3.3 7.3 0.0 3.1 3 0 0 3 3 2 0 CobW/HypB/UreG, nucleotide-binding domain UAA PF08449.11 OQS03182.1 - 0.044 13.0 0.0 0.049 12.8 0.0 1.0 1 0 0 1 1 1 0 UAA transporter family Peptidase_C1 PF00112.23 OQS03183.1 - 2.3e-78 263.2 4.7 1.1e-38 133.5 0.4 3.4 2 2 0 2 2 2 2 Papain family cysteine protease cNMP_binding PF00027.29 OQS03183.1 - 3.1e-19 68.8 0.0 7.4e-19 67.6 0.0 1.6 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Ion_trans PF00520.31 OQS03183.1 - 1.5e-11 44.0 11.1 3.9e-11 42.7 11.1 1.6 1 0 0 1 1 1 1 Ion transport protein Peptidase_C1_2 PF03051.15 OQS03183.1 - 0.0016 17.3 6.9 2.2 7.0 0.3 4.4 4 1 0 4 4 4 3 Peptidase C1-like family CEBP_ZZ PF16366.5 OQS03183.1 - 0.0038 17.4 6.0 0.27 11.5 0.7 2.8 2 0 0 2 2 2 2 Cytoplasmic polyadenylation element-binding protein ZZ domain cNMP_binding PF00027.29 OQS03184.1 - 2.6e-15 56.2 0.0 5.5e-15 55.2 0.0 1.5 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Ion_trans PF00520.31 OQS03184.1 - 5.8e-07 29.0 11.6 8.2e-07 28.5 11.6 1.3 1 0 0 1 1 1 1 Ion transport protein Utp11 PF03998.13 OQS03185.1 - 6e-71 239.2 21.3 6.8e-71 239.1 21.3 1.0 1 0 0 1 1 1 1 Utp11 protein Pkinase PF00069.25 OQS03188.1 - 9.3e-16 58.0 0.0 6.6e-09 35.5 0.0 2.5 2 1 1 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 OQS03188.1 - 2.1e-15 56.7 0.0 2.4e-08 33.6 0.0 3.1 2 1 1 3 3 3 3 Protein tyrosine kinase Pkinase_Tyr PF07714.17 OQS03189.1 - 1.2e-54 185.3 0.0 1.5e-54 185.1 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OQS03189.1 - 1.7e-51 175.1 0.0 2.2e-51 174.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 OQS03189.1 - 0.03 14.2 0.0 0.094 12.6 0.0 1.7 1 1 1 2 2 2 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 OQS03189.1 - 0.033 13.1 0.1 0.076 11.9 0.1 1.6 1 1 0 1 1 1 0 Haspin like kinase domain RIO1 PF01163.22 OQS03189.1 - 0.068 12.8 0.0 0.11 12.1 0.0 1.2 1 0 0 1 1 1 0 RIO1 family CCT PF06203.14 OQS03190.1 - 2.6e-11 43.4 8.5 4.4e-11 42.7 8.5 1.3 1 0 0 1 1 1 1 CCT motif Pkinase_Tyr PF07714.17 OQS03190.1 - 0.094 12.0 0.0 0.16 11.2 0.0 1.3 1 0 0 1 1 1 0 Protein tyrosine kinase PIN_9 PF18477.1 OQS03190.1 - 0.13 12.6 4.0 0.25 11.7 4.0 1.4 1 0 0 1 1 1 0 PIN like domain HD_3 PF13023.6 OQS03190.1 - 0.15 12.0 1.6 0.28 11.1 1.6 1.4 1 0 0 1 1 1 0 HD domain CBFB_NFYA PF02045.15 OQS03190.1 - 0.4 11.3 4.7 0.67 10.6 4.7 1.3 1 0 0 1 1 1 0 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B CKAP2_C PF15297.6 OQS03190.1 - 2.1 7.3 6.0 2.5 7.1 0.6 2.2 2 0 0 2 2 2 0 Cytoskeleton-associated protein 2 C-terminus Pkinase_Tyr PF07714.17 OQS03191.1 - 3.2e-13 49.6 0.0 7.1e-13 48.4 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OQS03191.1 - 6.5e-08 32.2 0.0 1.8e-07 30.8 0.0 1.7 1 0 0 1 1 1 1 Protein kinase domain WW PF00397.26 OQS03192.1 - 4.3e-08 33.1 0.7 1e-07 31.9 0.7 1.7 1 0 0 1 1 1 1 WW domain Thump_like PF18096.1 OQS03192.1 - 0.00031 20.6 0.9 0.014 15.3 0.0 3.7 4 0 0 4 4 4 1 THUMP domain-like Uso1_p115_C PF04871.13 OQS03192.1 - 0.0035 17.7 15.2 0.0035 17.7 15.2 15.4 5 3 8 14 14 14 4 Uso1 / p115 like vesicle tethering protein, C terminal region Ax_dynein_light PF10211.9 OQS03192.1 - 0.0059 16.6 10.0 0.0059 16.6 10.0 16.0 4 2 11 17 17 17 2 Axonemal dynein light chain PLAC9 PF15205.6 OQS03192.1 - 2.3 8.7 4.4 9.6 6.7 0.4 3.7 2 0 0 2 2 2 0 Placenta-specific protein 9 MBT PF02820.18 OQS03193.1 - 0.12 12.8 0.1 0.51 10.7 0.0 2.1 2 0 0 2 2 2 0 mbt repeat Ank_2 PF12796.7 OQS03194.1 - 5.5e-33 113.4 8.7 3e-12 46.9 0.4 3.1 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQS03194.1 - 3.7e-27 94.3 5.3 3.8e-10 40.1 0.0 4.3 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQS03194.1 - 1.1e-26 90.0 3.7 0.00025 21.2 0.0 5.5 5 0 0 5 5 5 5 Ankyrin repeat Ank_5 PF13857.6 OQS03194.1 - 1.3e-25 89.1 12.7 3.4e-11 43.1 0.8 4.4 2 2 1 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 OQS03194.1 - 3.9e-21 74.5 13.3 6.6e-06 26.3 0.6 5.4 6 0 0 6 6 6 4 Ankyrin repeat PI3_PI4_kinase PF00454.27 OQS03195.1 - 3.2e-43 148.3 0.0 4.6e-40 138.0 0.0 2.3 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase 7tm_3 PF00003.22 OQS03195.1 - 2.7e-13 50.2 26.1 4.6e-13 49.5 26.1 1.4 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR PI3Ka PF00613.20 OQS03195.1 - 1.5e-11 44.1 0.3 4.5e-11 42.5 0.3 1.8 2 0 0 2 2 2 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) DUF4135 PF13575.6 OQS03195.1 - 0.00072 19.0 0.0 0.0012 18.2 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4135) HA PF03457.14 OQS03196.1 - 2.1e-13 50.4 8.3 4e-07 30.3 0.1 3.7 4 0 0 4 4 4 2 Helicase associated domain ABC_membrane PF00664.23 OQS03197.1 - 4.1e-27 95.5 18.1 6.1e-27 95.0 18.1 1.3 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 OQS03197.1 - 1.1e-06 29.2 0.1 2.2e-06 28.3 0.1 1.5 1 0 0 1 1 1 1 ABC transporter RsgA_GTPase PF03193.16 OQS03197.1 - 0.0041 17.0 0.0 0.009 15.9 0.0 1.5 1 0 0 1 1 1 1 RsgA GTPase DUF3671 PF12420.8 OQS03197.1 - 1.5 8.9 9.3 1.7 8.8 2.3 3.3 2 2 0 2 2 2 0 Protein of unknown function Sugar_tr PF00083.24 OQS03198.1 - 5.3e-26 91.5 25.2 1.3e-24 86.9 25.2 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OQS03198.1 - 7.3e-16 58.0 27.3 2.9e-08 33.0 6.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3040 PF11239.8 OQS03198.1 - 0.07 13.4 4.0 4 7.8 0.1 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3040) Ras PF00071.22 OQS03199.1 - 8.1e-54 181.6 0.0 9.2e-54 181.4 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OQS03199.1 - 6.6e-21 74.7 0.0 9.5e-21 74.2 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OQS03199.1 - 1e-08 34.8 0.0 1.4e-08 34.4 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 OQS03199.1 - 0.00039 20.0 0.0 0.00076 19.1 0.0 1.4 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain FAST_2 PF08368.12 OQS03199.1 - 0.039 14.7 0.0 0.066 14.0 0.0 1.3 1 0 0 1 1 1 0 FAST kinase-like protein, subdomain 2 Cation_ATPase_C PF00689.21 OQS03200.1 - 7.9e-42 143.0 5.7 7.9e-42 143.0 5.7 2.1 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 OQS03200.1 - 9.3e-30 103.5 10.9 3.4e-20 72.3 0.7 2.9 3 0 0 3 3 3 2 E1-E2 ATPase Cation_ATPase PF13246.6 OQS03200.1 - 1.1e-19 70.2 0.1 2.5e-19 69.2 0.1 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 OQS03200.1 - 5.1e-15 56.3 0.1 4.8e-14 53.1 0.1 2.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 OQS03200.1 - 1.2e-12 47.3 0.0 3.4e-12 45.9 0.0 1.8 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 OQS03200.1 - 0.00037 20.3 0.4 0.0089 15.8 0.2 2.5 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase SRP_TPR_like PF17004.5 OQS03201.1 - 1.3e-15 57.4 9.1 2.1e-15 56.8 5.0 2.9 4 0 0 4 4 2 1 Putative TPR-like repeat TPR_6 PF13174.6 OQS03201.1 - 4.7e-12 45.7 5.9 0.72 10.6 0.4 7.4 7 0 0 7 7 6 4 Tetratricopeptide repeat TPR_2 PF07719.17 OQS03201.1 - 3.3e-10 39.3 15.2 0.0024 17.8 1.7 8.8 9 0 0 9 9 9 1 Tetratricopeptide repeat TPR_19 PF14559.6 OQS03201.1 - 1.4e-09 38.3 24.7 0.13 12.8 0.1 8.2 5 3 3 8 8 8 4 Tetratricopeptide repeat ANAPC3 PF12895.7 OQS03201.1 - 3.6e-09 36.7 13.4 3.7e-06 27.1 3.3 4.6 4 1 1 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.6 OQS03201.1 - 8.2e-06 26.2 19.4 0.15 12.9 0.5 9.1 6 2 6 12 12 10 1 Tetratricopeptide repeat SRP72 PF08492.12 OQS03201.1 - 1.1e-05 25.8 10.0 3.5e-05 24.2 10.0 1.9 1 0 0 1 1 1 1 SRP72 RNA-binding domain TPR_12 PF13424.6 OQS03201.1 - 0.00034 20.9 23.8 0.085 13.2 1.5 7.6 6 3 1 8 8 7 1 Tetratricopeptide repeat TPR_8 PF13181.6 OQS03201.1 - 0.0024 18.0 19.0 0.25 11.7 0.5 8.0 10 0 0 10 10 8 1 Tetratricopeptide repeat TPR_7 PF13176.6 OQS03201.1 - 0.005 16.8 3.5 0.98 9.6 0.5 4.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 OQS03201.1 - 0.01 16.4 16.0 0.5 11.1 0.3 5.6 5 1 0 5 5 4 0 Tetratricopeptide repeat TPR_1 PF00515.28 OQS03201.1 - 0.012 15.4 25.9 0.24 11.3 0.9 8.2 10 0 0 10 10 9 0 Tetratricopeptide repeat TPR_17 PF13431.6 OQS03201.1 - 0.085 13.3 3.8 7.4 7.2 0.2 4.9 5 0 0 5 5 4 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 OQS03201.1 - 0.16 12.0 4.8 0.53 10.4 0.3 3.8 4 1 1 5 5 4 0 Fis1 C-terminal tetratricopeptide repeat HrpB1_HrpK PF09613.10 OQS03201.1 - 0.18 11.4 2.1 8.1 6.1 0.2 4.0 2 1 2 4 4 4 0 Bacterial type III secretion protein (HrpB1_HrpK) Alkyl_sulf_dimr PF14863.6 OQS03201.1 - 0.61 10.5 7.3 2.6 8.5 0.1 3.4 4 0 0 4 4 3 0 Alkyl sulfatase dimerisation TPR_10 PF13374.6 OQS03201.1 - 1.6 8.7 10.4 19 5.3 0.8 6.0 6 0 0 6 6 6 0 Tetratricopeptide repeat Maf PF02545.14 OQS03201.1 - 3.2 7.6 7.7 2.4 8.0 0.1 3.3 2 1 0 3 3 3 0 Maf-like protein TPR_11 PF13414.6 OQS03201.1 - 8.4 6.2 12.6 8.9 6.1 0.1 4.5 6 0 0 6 6 5 0 TPR repeat Ribosomal_L19 PF01245.20 OQS03202.1 - 2e-24 85.7 0.5 2.5e-24 85.3 0.5 1.1 1 0 0 1 1 1 1 Ribosomal protein L19 VIT1 PF01988.19 OQS03203.1 - 1.3e-56 191.9 1.6 1.8e-56 191.4 1.6 1.2 1 0 0 1 1 1 1 VIT family ANAPC4_WD40 PF12894.7 OQS03204.1 - 1.5e-12 47.6 1.3 0.0054 17.0 0.1 4.9 4 1 1 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 OQS03204.1 - 0.00067 20.4 2.8 2.4 9.2 0.1 4.1 4 0 0 4 4 4 2 WD domain, G-beta repeat Coatomer_WDAD PF04053.14 OQS03204.1 - 0.0072 15.4 0.2 0.27 10.2 0.1 2.0 1 1 1 2 2 2 2 Coatomer WD associated region RAB3GAP2_N PF14655.6 OQS03204.1 - 0.011 15.0 0.1 0.46 9.7 0.0 2.1 2 0 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus AtpR PF12966.7 OQS03204.1 - 0.3 11.6 2.7 0.59 10.6 2.7 1.5 1 0 0 1 1 1 0 N-ATPase, AtpR subunit Peptidase_S8 PF00082.22 OQS03206.1 - 2.1e-31 109.3 0.9 2.5e-31 109.1 0.9 1.0 1 0 0 1 1 1 1 Subtilase family Peripla_BP_1 PF00532.21 OQS03206.1 - 0.0089 15.5 0.0 0.012 15.0 0.0 1.2 1 0 0 1 1 1 1 Periplasmic binding proteins and sugar binding domain of LacI family ScsC_N PF18312.1 OQS03206.1 - 0.086 12.7 0.3 0.15 11.9 0.3 1.3 1 0 0 1 1 1 0 Copper resistance protein ScsC N-terminal domain HECT PF00632.25 OQS03207.1 - 5.8e-92 308.5 0.3 9.6e-92 307.7 0.3 1.4 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) UCH PF00443.29 OQS03207.1 - 1.8e-46 158.7 0.0 3.2e-46 157.9 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 OQS03207.1 - 0.00087 19.0 0.3 0.00087 19.0 0.3 2.9 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase IQ PF00612.27 OQS03207.1 - 0.014 15.1 0.5 0.04 13.7 0.5 1.8 1 0 0 1 1 1 0 IQ calmodulin-binding motif BES1_N PF05687.13 OQS03207.1 - 0.69 10.3 6.8 2.6 8.4 6.8 2.1 1 0 0 1 1 1 0 BES1/BZR1 plant transcription factor, N-terminal Ipi1_N PF12333.8 OQS03207.1 - 1.5 9.4 0.0 1.5 9.4 0.0 3.2 3 0 0 3 3 3 0 Rix1 complex component involved in 60S ribosome maturation PH PF00169.29 OQS03212.1 - 2.2e-22 79.5 0.0 5.1e-16 59.1 0.1 2.2 1 1 1 2 2 2 2 PH domain PH_11 PF15413.6 OQS03212.1 - 3.6e-07 30.6 1.4 5.2e-05 23.6 0.6 2.4 1 1 1 2 2 2 2 Pleckstrin homology domain HHH_3 PF12836.7 OQS03213.1 - 0.053 13.8 0.1 0.093 13.0 0.1 1.4 1 0 0 1 1 1 0 Helix-hairpin-helix motif TTL PF03133.15 OQS03214.1 - 3.9e-46 157.5 0.2 4.5e-46 157.3 0.2 1.0 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family HECT PF00632.25 OQS03217.1 - 6.1e-77 259.1 0.0 8.9e-77 258.6 0.0 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) zf-RanBP PF00641.18 OQS03217.1 - 0.00017 20.8 1.4 0.00038 19.7 1.4 1.5 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others DUF4903 PF16246.5 OQS03217.1 - 0.095 12.3 0.0 0.19 11.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4903) DZR PF12773.7 OQS03217.1 - 0.1 12.6 0.9 0.18 11.8 0.9 1.3 1 0 0 1 1 1 0 Double zinc ribbon cobW PF02492.19 OQS03218.1 - 2.7e-34 118.3 0.7 5.3e-34 117.3 0.7 1.4 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.14 OQS03218.1 - 3.2e-10 39.8 0.0 6.9e-10 38.7 0.0 1.6 1 0 0 1 1 1 1 Cobalamin synthesis protein cobW C-terminal domain Viral_helicase1 PF01443.18 OQS03218.1 - 0.018 14.8 0.0 0.039 13.7 0.0 1.6 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase ATPase_2 PF01637.18 OQS03218.1 - 0.041 13.8 0.0 0.094 12.6 0.0 1.5 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_14 PF13173.6 OQS03218.1 - 0.054 13.5 0.0 0.14 12.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 OQS03218.1 - 0.068 13.5 0.0 0.18 12.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 OQS03218.1 - 0.078 13.0 0.0 0.23 11.5 0.0 1.7 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_16 PF13191.6 OQS03218.1 - 0.15 12.5 0.0 0.37 11.2 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain DDE_3 PF13358.6 OQS03219.1 - 1.6e-05 24.7 0.0 5.6e-05 22.9 0.0 1.9 2 0 0 2 2 2 1 DDE superfamily endonuclease Otopetrin PF03189.13 OQS03220.1 - 0.01 14.7 0.0 0.01 14.7 0.0 1.0 1 0 0 1 1 1 0 Otopetrin Cytochrom_B_C PF00032.17 OQS03220.1 - 0.015 15.6 0.3 0.022 15.0 0.3 1.3 1 0 0 1 1 1 0 Cytochrome b(C-terminal)/b6/petD COX2_TM PF02790.15 OQS03220.1 - 0.1 12.7 0.2 0.39 10.9 0.0 1.9 1 1 1 2 2 2 0 Cytochrome C oxidase subunit II, transmembrane domain TRP PF06011.12 OQS03220.1 - 0.12 11.0 0.3 0.15 10.7 0.3 1.1 1 0 0 1 1 1 0 Transient receptor potential (TRP) ion channel PHD PF00628.29 OQS03221.1 - 5.5e-16 58.2 34.6 4.7e-11 42.4 8.0 3.0 3 0 0 3 3 3 2 PHD-finger Vps36-NZF-N PF16988.5 OQS03221.1 - 0.047 13.1 9.7 0.77 9.2 0.1 4.0 4 0 0 4 4 4 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain Kinesin PF00225.23 OQS03222.1 - 2.6e-83 279.7 0.5 3.7e-83 279.2 0.5 1.2 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 OQS03222.1 - 1.4e-10 41.3 0.0 3.1e-10 40.2 0.0 1.5 1 0 0 1 1 1 1 Microtubule binding Ank_2 PF12796.7 OQS03223.1 - 2.7e-13 50.3 0.4 5.9e-13 49.2 0.4 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 OQS03223.1 - 8.1e-13 48.2 3.7 1.2e-05 25.5 0.3 2.6 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.6 OQS03223.1 - 2.1e-11 44.1 5.3 2.3e-07 31.2 0.5 2.4 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQS03223.1 - 7.2e-10 38.3 1.8 0.00029 21.1 0.3 2.6 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.6 OQS03223.1 - 2.4e-06 27.7 1.3 0.00057 20.1 0.1 2.5 2 0 0 2 2 2 2 Ankyrin repeats (many copies) MRC1 PF09444.10 OQS03223.1 - 3e-05 24.6 12.0 3e-05 24.6 12.0 5.8 3 2 2 6 6 6 1 MRC1-like domain DUF4574 PF15141.6 OQS03223.1 - 2.3 8.2 10.5 0.086 12.8 2.7 2.8 2 0 0 2 2 2 0 Ubiquinol-cytochrome-c reductase complex assembly factor 3 WD40 PF00400.32 OQS03225.1 - 2.6e-27 94.5 20.6 1e-05 26.1 0.0 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat NLE PF08154.12 OQS03225.1 - 3.7e-21 75.4 0.1 7e-21 74.5 0.1 1.5 1 0 0 1 1 1 1 NLE (NUC135) domain Nucleoporin_N PF08801.11 OQS03225.1 - 8.7e-05 21.4 1.0 0.00033 19.5 0.7 1.8 1 1 1 2 2 2 1 Nup133 N terminal like PGI PF00342.19 OQS03226.1 - 3e-193 642.9 0.0 3.7e-193 642.5 0.0 1.1 1 0 0 1 1 1 1 Phosphoglucose isomerase Ribosomal_TL5_C PF14693.6 OQS03227.1 - 4.6e-20 71.8 0.0 9.5e-20 70.8 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein TL5, C-terminal domain Ribosomal_L25p PF01386.19 OQS03227.1 - 3.3e-16 59.5 0.0 7.3e-16 58.5 0.0 1.6 1 0 0 1 1 1 1 Ribosomal L25p family RPAP1_N PF08621.10 OQS03227.1 - 0.045 13.5 0.0 0.12 12.2 0.0 1.7 1 0 0 1 1 1 0 RPAP1-like, N-terminal Cpn60_TCP1 PF00118.24 OQS03229.1 - 2.5e-146 488.2 9.8 2.8e-146 488.0 9.8 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Nucleoporin_C PF03177.14 OQS03231.1 - 8e-05 21.6 0.3 0.00021 20.2 0.3 1.7 1 0 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal Chromo PF00385.24 OQS03232.1 - 4.5e-10 39.3 0.2 7.9e-10 38.5 0.2 1.4 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain STIMATE PF12400.8 OQS03232.1 - 0.042 14.4 0.1 0.042 14.4 0.1 2.1 1 1 0 2 2 2 0 STIMATE family YhhN PF07947.14 OQS03232.1 - 1 9.0 8.4 0.16 11.5 4.7 1.6 2 0 0 2 2 2 0 YhhN family 7TMR-DISM_7TM PF07695.11 OQS03232.1 - 7.1 6.5 14.8 1.1 9.1 9.5 1.9 1 1 1 2 2 2 0 7TM diverse intracellular signalling HMG_box PF00505.19 OQS03233.1 - 2.2e-21 76.0 0.4 4.1e-21 75.2 0.4 1.4 1 0 0 1 1 1 1 HMG (high mobility group) box CBFD_NFYB_HMF PF00808.23 OQS03233.1 - 7.9e-20 70.9 0.2 1.5e-19 70.0 0.2 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone HMG_box_2 PF09011.10 OQS03233.1 - 2.2e-12 47.4 0.1 3.9e-12 46.6 0.1 1.4 1 0 0 1 1 1 1 HMG-box domain Histone PF00125.24 OQS03233.1 - 2e-06 28.2 0.2 4.6e-06 27.0 0.2 1.7 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 OQS03233.1 - 0.00013 22.0 0.1 0.00035 20.6 0.0 1.6 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold CHDNT PF08073.12 OQS03233.1 - 0.0027 17.6 0.0 0.006 16.5 0.0 1.6 1 0 0 1 1 1 1 CHDNT (NUC034) domain PDZ_6 PF17820.1 OQS03236.1 - 3e-07 30.2 0.0 0.034 14.0 0.0 3.1 3 0 0 3 3 3 2 PDZ domain PDZ PF00595.24 OQS03236.1 - 9.8e-05 22.6 0.1 0.51 10.7 0.0 2.7 2 0 0 2 2 2 2 PDZ domain DUF2124 PF09897.9 OQS03236.1 - 0.087 12.7 0.0 0.23 11.4 0.0 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2124) Ribosomal_L22e PF01776.17 OQS03237.1 - 3.5e-47 159.3 2.2 4.5e-47 159.0 2.2 1.0 1 0 0 1 1 1 1 Ribosomal L22e protein family MPP6 PF10175.9 OQS03238.1 - 1.2e-11 45.3 0.8 1.2e-11 45.3 0.8 3.2 2 1 1 3 3 3 1 M-phase phosphoprotein 6 SHIPPO-rpt PF07004.12 OQS03238.1 - 0.057 14.4 13.4 8.5 7.5 0.3 4.4 4 0 0 4 4 4 0 Sperm-tail PG-rich repeat DUF4275 PF14101.6 OQS03238.1 - 6.3 6.9 7.4 0.56 10.3 0.5 2.5 2 1 1 3 3 3 0 Domain of unknown function (DUF4275) Ras PF00071.22 OQS03239.1 - 7.2e-41 139.5 0.1 9.3e-41 139.1 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OQS03239.1 - 4.2e-26 91.5 0.0 6.9e-26 90.8 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OQS03239.1 - 2.9e-09 36.6 0.1 3.7e-09 36.3 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 OQS03239.1 - 0.0035 16.7 0.1 0.0044 16.4 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region XFP_N PF09364.10 OQS03239.1 - 0.017 13.9 0.0 5.4 5.7 0.0 2.3 1 1 1 2 2 2 0 XFP N-terminal domain Radical_SAM_C PF16199.5 OQS03240.1 - 3.6e-33 113.4 0.1 1.4e-32 111.6 0.0 2.1 2 0 0 2 2 2 1 Radical_SAM C-terminal domain Radical_SAM PF04055.21 OQS03240.1 - 1.2e-16 61.6 0.1 1e-15 58.5 0.1 2.4 2 0 0 2 2 2 1 Radical SAM superfamily Acetyltransf_1 PF00583.25 OQS03240.1 - 2.1e-08 34.4 0.0 4.4e-08 33.4 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 OQS03240.1 - 5.8e-07 29.5 0.1 3.7e-06 26.9 0.0 2.2 3 0 0 3 3 3 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 OQS03240.1 - 0.0031 17.9 0.0 0.0067 16.8 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 OQS03240.1 - 0.0033 17.4 0.0 0.0094 15.9 0.0 1.7 1 0 0 1 1 1 1 FR47-like protein Ank_2 PF12796.7 OQS03241.1 - 9.8e-28 96.6 1.2 1.1e-14 54.8 0.1 2.7 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQS03241.1 - 1.1e-21 76.9 0.7 1.7e-10 41.2 0.1 3.1 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 OQS03241.1 - 4.8e-21 74.2 0.0 1.7e-06 28.2 0.0 3.5 3 0 0 3 3 3 3 Ankyrin repeat Ank_3 PF13606.6 OQS03241.1 - 3.8e-18 63.7 0.0 0.00032 20.9 0.0 4.2 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.6 OQS03241.1 - 4e-16 58.9 0.1 0.00037 20.7 0.0 3.3 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Piezo_RRas_bdg PF12166.8 OQS03242.1 - 2.6e-69 234.5 0.0 5e-69 233.6 0.0 1.4 1 0 0 1 1 1 1 Piezo non-specific cation channel, R-Ras-binding domain EF-hand_1 PF00036.32 OQS03242.1 - 1e-14 52.9 7.8 2.1e-05 23.8 0.4 3.7 3 0 0 3 3 3 3 EF hand EF-hand_7 PF13499.6 OQS03242.1 - 9.5e-13 48.4 1.9 5.4e-08 33.2 0.3 2.7 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 OQS03242.1 - 2.5e-12 45.6 2.1 1.6e-05 24.5 0.0 4.0 3 0 0 3 3 3 3 EF-hand domain EF-hand_8 PF13833.6 OQS03242.1 - 7.2e-11 41.8 4.8 1.4e-06 28.1 0.2 3.0 2 1 1 3 3 3 2 EF-hand domain pair fn3 PF00041.21 OQS03242.1 - 9e-11 42.0 0.0 2.4e-10 40.6 0.0 1.8 1 0 0 1 1 1 1 Fibronectin type III domain EF-hand_5 PF13202.6 OQS03242.1 - 3.1e-09 35.9 6.4 0.013 14.9 0.0 3.6 3 0 0 3 3 3 3 EF hand EF-hand_9 PF14658.6 OQS03242.1 - 1e-06 29.0 0.8 0.00027 21.2 0.0 3.5 3 0 0 3 3 3 1 EF-hand domain fn3_2 PF16893.5 OQS03242.1 - 0.013 15.6 0.1 0.17 12.1 0.0 2.6 2 0 0 2 2 2 0 Fibronectin type III domain DUF3687 PF12459.8 OQS03242.1 - 0.03 13.9 0.8 0.23 11.0 0.8 2.7 1 0 0 1 1 1 0 D-Ala-teichoic acid biosynthesis protein Pur_ac_phosph_N PF16656.5 OQS03242.1 - 0.061 13.9 0.0 0.45 11.1 0.0 2.4 2 0 0 2 2 2 0 Purple acid Phosphatase, N-terminal domain HSF_DNA-bind PF00447.17 OQS03243.1 - 1e-23 83.8 0.1 1.8e-23 83.0 0.1 1.4 1 0 0 1 1 1 1 HSF-type DNA-binding Choline_transpo PF04515.12 OQS03244.1 - 1.4e-27 96.8 24.7 1.4e-27 96.8 24.7 2.1 1 1 1 2 2 2 1 Plasma-membrane choline transporter WD40 PF00400.32 OQS03245.1 - 9.3e-13 48.5 0.4 0.037 14.9 0.1 5.8 5 0 0 5 5 5 4 WD domain, G-beta repeat WD40_like PF17005.5 OQS03245.1 - 0.0005 19.5 0.0 0.0009 18.7 0.0 1.4 1 0 0 1 1 1 1 WD40-like domain BBS2_N PF14781.6 OQS03245.1 - 0.049 13.5 0.0 0.14 12.1 0.0 1.8 1 0 0 1 1 1 0 Ciliary BBSome complex subunit 2, N-terminal Me-amine-dh_H PF06433.11 OQS03245.1 - 0.051 12.4 0.1 1.4 7.7 0.1 2.2 2 0 0 2 2 2 0 Methylamine dehydrogenase heavy chain (MADH) SGL PF08450.12 OQS03245.1 - 0.12 11.9 0.1 23 4.5 0.0 3.0 2 1 1 3 3 3 0 SMP-30/Gluconolactonase/LRE-like region Alg6_Alg8 PF03155.15 OQS03246.1 - 8.4e-158 526.3 24.5 9.8e-158 526.1 24.5 1.0 1 0 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family Ribosomal_60s PF00428.19 OQS03247.1 - 4.4e-21 75.3 15.2 5.1e-21 75.1 15.2 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein LETM1 PF07766.13 OQS03248.1 - 2.2e-37 128.9 0.0 2.9e-37 128.5 0.0 1.2 1 0 0 1 1 1 1 LETM1-like protein AhpC-TSA PF00578.21 OQS03249.1 - 2.6e-35 121.0 0.1 5e-35 120.1 0.0 1.5 2 0 0 2 2 2 1 AhpC/TSA family Redoxin PF08534.10 OQS03249.1 - 6.4e-14 51.9 0.0 8.9e-14 51.4 0.0 1.2 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.9 OQS03249.1 - 8.7e-10 38.3 0.0 1.5e-09 37.5 0.0 1.4 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin SCO1-SenC PF02630.14 OQS03249.1 - 0.11 12.5 0.0 0.24 11.3 0.0 1.5 1 0 0 1 1 1 0 SCO1/SenC Asparaginase PF00710.20 OQS03250.1 - 1.2e-12 47.8 0.1 1.9e-12 47.1 0.1 1.3 1 0 0 1 1 1 1 Asparaginase, N-terminal DSPc PF00782.20 OQS03250.1 - 9.9e-07 28.6 0.1 1.8e-06 27.8 0.1 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 OQS03250.1 - 0.013 15.1 0.1 0.023 14.3 0.1 1.4 1 0 0 1 1 1 0 Protein-tyrosine phosphatase CDKN3 PF05706.12 OQS03250.1 - 0.015 14.9 0.0 0.028 14.1 0.0 1.4 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) FSH1 PF03959.13 OQS03251.1 - 2.2e-35 122.3 0.0 3.6e-35 121.6 0.0 1.3 1 0 0 1 1 1 1 Serine hydrolase (FSH1) VPS9 PF02204.18 OQS03251.1 - 1.5e-12 47.6 1.0 4e-12 46.3 1.0 1.8 1 1 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain DLH PF01738.18 OQS03251.1 - 0.0013 18.4 0.0 0.0033 17.0 0.0 1.6 2 0 0 2 2 2 1 Dienelactone hydrolase family Abhydrolase_2 PF02230.16 OQS03251.1 - 0.0069 16.2 0.0 0.017 14.9 0.0 1.7 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Ser_hydrolase PF06821.13 OQS03251.1 - 0.018 14.9 0.0 0.035 13.9 0.0 1.4 1 0 0 1 1 1 0 Serine hydrolase Abhydrolase_1 PF00561.20 OQS03251.1 - 0.027 14.1 0.0 7.6 6.1 0.0 2.6 2 0 0 2 2 2 0 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 OQS03251.1 - 0.04 13.2 0.0 0.16 11.2 0.0 2.0 1 1 1 2 2 2 0 Serine aminopeptidase, S33 TMP-TENI PF02581.17 OQS03252.1 - 7.1e-16 58.0 0.0 1.4e-15 57.1 0.0 1.5 1 0 0 1 1 1 1 Thiamine monophosphate synthase HEAT_2 PF13646.6 OQS03252.1 - 2.9e-06 27.6 0.1 0.054 13.9 0.0 3.8 4 0 0 4 4 4 2 HEAT repeats HEAT PF02985.22 OQS03252.1 - 5.1e-06 26.3 11.1 0.068 13.5 0.1 6.7 7 0 0 7 7 7 3 HEAT repeat PDZ_2 PF13180.6 OQS03252.1 - 0.0038 17.5 0.0 2.5 8.5 0.0 2.8 2 1 0 2 2 2 2 PDZ domain MIF4G_like_2 PF09090.11 OQS03253.1 - 1.2e-24 87.3 6.2 6.1e-24 84.9 4.1 2.7 2 1 0 2 2 2 1 MIF4G like MIF4G_like PF09088.11 OQS03253.1 - 7.8e-18 64.9 1.4 2.2e-16 60.2 1.1 2.8 2 1 0 2 2 2 1 MIF4G like CUE PF02845.16 OQS03254.1 - 0.0017 18.0 0.0 0.0033 17.1 0.0 1.4 1 0 0 1 1 1 1 CUE domain EamA PF00892.20 OQS03255.1 - 8.2e-20 71.4 39.0 5.4e-15 55.8 14.4 2.0 2 0 0 2 2 2 2 EamA-like transporter family Ank_2 PF12796.7 OQS03256.1 - 1.1e-22 80.4 11.2 2.2e-10 41.0 0.7 4.9 1 1 7 8 8 8 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQS03256.1 - 4e-17 62.3 7.2 0.0018 18.8 0.0 5.7 2 2 4 6 6 6 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQS03256.1 - 1.8e-14 52.4 9.5 0.011 16.2 0.0 7.3 7 0 0 7 7 7 4 Ankyrin repeat Ank_5 PF13857.6 OQS03256.1 - 5.3e-13 48.9 6.3 0.0056 17.0 0.0 5.6 5 1 1 6 6 6 4 Ankyrin repeats (many copies) Ank PF00023.30 OQS03256.1 - 2.4e-11 43.5 9.6 0.2 12.2 0.0 6.9 7 0 0 7 7 7 4 Ankyrin repeat Chibby PF14645.6 OQS03257.1 - 0.13 12.7 2.0 0.27 11.6 2.0 1.5 1 0 0 1 1 1 0 Chibby family Pkinase PF00069.25 OQS03258.1 - 1.1e-64 218.4 0.0 1.6e-64 217.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQS03258.1 - 7.2e-29 100.8 0.0 1.2e-28 100.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase PH PF00169.29 OQS03258.1 - 7.8e-10 39.2 3.0 1.1e-05 25.9 0.4 3.6 3 0 0 3 3 3 2 PH domain GAF_2 PF13185.6 OQS03258.1 - 0.0011 19.3 0.0 0.0024 18.2 0.0 1.6 1 0 0 1 1 1 1 GAF domain PH_9 PF15410.6 OQS03258.1 - 0.0029 18.0 0.5 4.6 7.6 0.1 3.4 4 0 0 4 4 4 2 Pleckstrin homology domain GAF PF01590.26 OQS03258.1 - 0.006 17.2 0.0 0.031 14.9 0.0 2.2 2 0 0 2 2 2 1 GAF domain Haspin_kinase PF12330.8 OQS03258.1 - 0.0063 15.5 0.1 0.014 14.4 0.1 1.6 1 0 0 1 1 1 1 Haspin like kinase domain PH_8 PF15409.6 OQS03258.1 - 0.019 15.2 0.3 2.3 8.6 0.0 3.6 3 0 0 3 3 3 0 Pleckstrin homology domain PH_11 PF15413.6 OQS03258.1 - 3.6 8.1 6.5 1.9 9.0 0.2 3.7 4 0 0 4 4 4 0 Pleckstrin homology domain VASt PF16016.5 OQS03259.1 - 2.2e-37 128.8 4.4 6.4e-17 62.4 0.5 3.7 3 0 0 3 3 3 3 VAD1 Analog of StAR-related lipid transfer domain PUB PF09409.10 OQS03259.1 - 1.9e-18 66.2 0.0 4e-18 65.1 0.0 1.6 1 0 0 1 1 1 1 PUB domain ubiquitin PF00240.23 OQS03259.1 - 1.4e-13 50.4 0.1 4.4e-13 48.8 0.1 2.0 1 0 0 1 1 1 1 Ubiquitin family PH PF00169.29 OQS03259.1 - 7.6e-07 29.6 0.1 2.9e-06 27.7 0.1 2.1 1 0 0 1 1 1 1 PH domain Rad60-SLD PF11976.8 OQS03259.1 - 0.0002 21.1 0.0 0.00065 19.5 0.0 1.9 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 OQS03259.1 - 0.0022 18.5 0.1 0.017 15.7 0.0 2.5 3 0 0 3 3 3 1 DUF2407 ubiquitin-like domain DUF366 PF04017.12 OQS03259.1 - 0.044 13.2 1.1 0.068 12.6 0.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF366) PMC2NT PF08066.12 OQS03259.1 - 0.23 12.2 0.0 0.23 12.2 0.0 3.0 4 0 0 4 4 4 0 PMC2NT (NUC016) domain DHHW PF14286.6 OQS03259.1 - 1.7 7.9 4.9 3.4 6.9 4.9 1.4 1 0 0 1 1 1 0 DHHW protein EGF PF00008.27 OQS03260.1 - 0.0014 18.9 8.9 0.0014 18.9 8.9 5.6 4 1 0 4 4 4 3 EGF-like domain Nodulin_late PF07127.11 OQS03260.1 - 0.013 15.9 0.1 0.013 15.9 0.1 5.4 5 1 0 5 5 5 0 Late nodulin protein EGF_2 PF07974.13 OQS03260.1 - 0.23 11.9 80.3 0.23 11.9 14.0 6.5 5 1 0 5 5 5 0 EGF-like domain ABC_membrane PF00664.23 OQS03262.1 - 2.2e-38 132.5 16.9 3e-38 132.0 16.9 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 OQS03262.1 - 9.8e-31 107.1 0.0 1.6e-30 106.4 0.0 1.4 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 OQS03262.1 - 1.6e-05 24.5 1.2 0.077 12.4 0.1 2.2 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 OQS03262.1 - 0.0041 16.8 0.7 0.024 14.4 0.1 2.3 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_22 PF13401.6 OQS03262.1 - 0.0043 17.3 0.0 0.0098 16.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.23 OQS03262.1 - 0.0066 16.5 0.0 0.014 15.4 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF87 PF01935.17 OQS03262.1 - 0.016 15.3 0.1 0.036 14.1 0.1 1.6 1 0 0 1 1 1 0 Helicase HerA, central domain AAA_23 PF13476.6 OQS03262.1 - 0.018 15.6 0.0 0.036 14.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_21 PF13304.6 OQS03262.1 - 0.025 14.4 0.0 0.19 11.5 0.0 2.0 1 1 1 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 OQS03262.1 - 0.052 13.9 0.0 0.12 12.8 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain NB-ARC PF00931.22 OQS03262.1 - 0.067 12.4 0.1 0.21 10.8 0.1 1.7 1 1 0 1 1 1 0 NB-ARC domain PALP PF00291.25 OQS03264.1 - 2.1e-65 221.0 0.1 2.4e-65 220.8 0.1 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme MFS_1_like PF12832.7 OQS03265.1 - 1e-129 432.8 55.3 9.8e-66 222.2 23.2 2.4 2 1 0 2 2 2 2 MFS_1 like family MFS_1 PF07690.16 OQS03265.1 - 3.3e-43 148.0 75.4 2.4e-13 49.7 22.8 4.0 1 1 3 4 4 4 4 Major Facilitator Superfamily Nuc_H_symport PF03825.16 OQS03265.1 - 6.5e-27 94.5 44.3 6.9e-14 51.6 18.0 2.2 2 0 0 2 2 2 2 Nucleoside H+ symporter LacY_symp PF01306.19 OQS03265.1 - 3.2e-14 52.5 40.9 8.3e-08 31.4 16.2 2.2 2 0 0 2 2 2 2 LacY proton/sugar symporter MFS_3 PF05977.13 OQS03265.1 - 7.6e-11 41.1 35.0 2.3e-07 29.6 14.1 2.6 1 1 2 3 3 3 2 Transmembrane secretion effector MFS_2 PF13347.6 OQS03265.1 - 1.2e-09 37.2 48.6 0.0015 17.2 4.2 4.4 2 2 2 4 4 4 4 MFS/sugar transport protein GST_C_3 PF14497.6 OQS03265.1 - 0.00031 20.9 0.0 0.00077 19.6 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain YqfD PF06898.11 OQS03265.1 - 0.063 12.1 0.0 0.1 11.4 0.0 1.2 1 0 0 1 1 1 0 Putative stage IV sporulation protein YqfD GST_C_2 PF13410.6 OQS03265.1 - 0.087 12.9 0.0 0.25 11.4 0.0 1.7 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain CDP-OH_P_tran_2 PF08009.11 OQS03265.1 - 6.1 6.8 11.9 6 6.9 0.2 3.7 3 0 0 3 3 3 0 CDP-alcohol phosphatidyltransferase 2 SDF PF00375.18 OQS03266.1 - 1.4e-110 370.0 66.9 1.3e-71 241.7 44.6 3.0 2 1 0 2 2 2 2 Sodium:dicarboxylate symporter family DUF5409 PF17421.2 OQS03266.1 - 0.37 11.5 10.0 1.6 9.5 0.2 3.6 3 0 0 3 3 3 0 Family of unknown function (DUF5409) Bac_globin PF01152.21 OQS03267.1 - 1.1e-05 25.6 0.0 1.6e-05 25.0 0.0 1.3 1 0 0 1 1 1 1 Bacterial-like globin DEAD_2 PF06733.15 OQS03268.1 - 2.9e-51 173.6 0.6 5.1e-51 172.8 0.6 1.4 1 0 0 1 1 1 1 DEAD_2 Helicase_C_2 PF13307.6 OQS03268.1 - 2e-41 142.0 0.0 9e-41 139.9 0.0 2.1 2 0 0 2 2 2 1 Helicase C-terminal domain HBB PF06777.11 OQS03268.1 - 4.5e-37 127.6 1.1 7e-32 110.7 0.1 2.8 3 0 0 3 3 3 2 Helical and beta-bridge domain MMADHC PF10229.9 OQS03268.1 - 1.1e-26 94.2 0.0 1.8e-26 93.5 0.0 1.2 1 0 0 1 1 1 1 Methylmalonic aciduria and homocystinuria type D protein ResIII PF04851.15 OQS03268.1 - 3.3e-05 23.9 0.0 0.0016 18.5 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.29 OQS03268.1 - 0.00071 19.4 0.2 0.031 14.1 0.0 2.4 2 0 0 2 2 2 1 DEAD/DEAH box helicase SNF2_N PF00176.23 OQS03268.1 - 0.2 10.3 0.3 2.4 6.8 0.3 2.2 1 1 0 1 1 1 0 SNF2 family N-terminal domain DUF4504 PF14953.6 OQS03269.1 - 9.7e-12 44.8 0.3 6e-11 42.2 0.3 1.9 1 1 0 1 1 1 1 Domain of unknown function (DUF4504) tRNA_U5-meth_tr PF05958.11 OQS03270.1 - 4.4e-16 58.8 0.8 9e-16 57.8 0.0 1.8 2 0 0 2 2 2 1 tRNA (Uracil-5-)-methyltransferase Methyltransf_31 PF13847.6 OQS03270.1 - 1.4e-05 24.9 0.2 3.5e-05 23.6 0.2 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OQS03270.1 - 5.4e-05 23.8 0.1 0.00015 22.4 0.1 1.8 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 OQS03270.1 - 8.6e-05 22.2 0.1 0.00045 19.8 0.1 2.1 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_4 PF02390.17 OQS03270.1 - 0.00039 19.9 0.1 0.00092 18.7 0.1 1.6 1 0 0 1 1 1 1 Putative methyltransferase PrmA PF06325.13 OQS03270.1 - 0.00052 19.5 0.4 0.0013 18.2 0.4 1.6 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Cons_hypoth95 PF03602.15 OQS03270.1 - 0.016 14.9 0.3 0.042 13.5 0.0 1.8 2 0 0 2 2 2 0 Conserved hypothetical protein 95 Methyltransf_32 PF13679.6 OQS03270.1 - 0.022 14.8 2.1 0.025 14.6 0.0 2.1 3 0 0 3 3 3 0 Methyltransferase domain Met_10 PF02475.16 OQS03270.1 - 0.025 14.4 0.3 0.061 13.1 0.0 1.8 2 0 0 2 2 2 0 Met-10+ like-protein RRM_1 PF00076.22 OQS03270.1 - 0.089 12.6 0.0 0.47 10.3 0.0 2.1 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Methyltransf_15 PF09445.10 OQS03270.1 - 0.09 12.3 0.1 0.47 10.0 0.0 2.0 2 0 0 2 2 2 0 RNA cap guanine-N2 methyltransferase Methyltransf_11 PF08241.12 OQS03270.1 - 0.16 12.6 0.1 0.61 10.8 0.1 2.0 1 0 0 1 1 1 0 Methyltransferase domain Ank_2 PF12796.7 OQS03271.1 - 4.6e-33 113.6 10.6 8.5e-08 32.7 0.1 7.3 6 1 3 9 9 9 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQS03271.1 - 7.3e-28 96.6 15.3 2.9e-06 27.7 0.0 9.7 7 2 4 11 11 11 8 Ankyrin repeats (many copies) Ank_5 PF13857.6 OQS03271.1 - 7.1e-21 74.0 16.8 0.008 16.5 0.1 12.2 3 3 10 13 13 13 8 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQS03271.1 - 2.2e-17 61.3 12.7 3 8.7 0.0 15.3 15 2 2 17 17 17 3 Ankyrin repeat Ank PF00023.30 OQS03271.1 - 0.00021 21.6 11.2 17 6.1 0.5 9.3 7 3 1 8 8 8 1 Ankyrin repeat Ank_2 PF12796.7 OQS03272.1 - 9.7e-32 109.4 12.5 2.6e-07 31.1 0.1 6.8 5 1 1 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQS03272.1 - 3.3e-27 94.5 10.5 5e-05 23.8 0.0 9.5 6 2 5 11 11 11 9 Ankyrin repeats (many copies) Ank_5 PF13857.6 OQS03272.1 - 8.2e-19 67.4 15.5 0.28 11.5 0.1 11.3 4 3 7 11 11 11 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQS03272.1 - 8e-15 53.5 8.7 12 6.8 0.0 12.7 12 1 1 13 13 13 2 Ankyrin repeat DUF5049 PF16468.5 OQS03272.1 - 0.00011 22.0 1.2 8.2 6.4 0.1 5.7 5 1 1 6 6 6 1 Domain of unknown function (DUF5049) Ank PF00023.30 OQS03272.1 - 0.0013 19.1 6.7 66 4.2 0.3 8.7 5 4 0 5 5 5 0 Ankyrin repeat Phage_T7_Capsid PF05396.11 OQS03272.1 - 0.14 12.6 0.3 48 4.3 0.0 3.7 4 1 0 4 4 4 0 Phage T7 capsid assembly protein RCC1 PF00415.18 OQS03273.1 - 1.1e-56 189.2 15.4 1.8e-16 60.5 0.2 7.9 7 1 0 7 7 7 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 OQS03273.1 - 3.6e-36 122.2 46.0 6.6e-10 38.5 1.5 7.4 7 0 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat VPS9 PF02204.18 OQS03273.1 - 0.0022 18.2 0.2 0.0043 17.3 0.2 1.4 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain DUF1459 PF07312.11 OQS03273.1 - 9.9 6.5 7.6 19 5.5 0.0 3.3 2 1 1 3 3 3 0 Protein of unknown function (DUF1459) TMEM100 PF16311.5 OQS03274.1 - 0.52 9.9 4.0 0.28 10.8 1.1 2.0 2 0 0 2 2 2 0 Transmembrane protein 100 EamA PF00892.20 OQS03276.1 - 9.1e-15 55.0 41.3 5.5e-11 42.8 17.1 2.1 2 0 0 2 2 2 2 EamA-like transporter family TPT PF03151.16 OQS03276.1 - 1.8 7.9 15.8 0.014 14.8 5.5 2.1 1 1 1 2 2 2 0 Triose-phosphate Transporter family Aminotran_5 PF00266.19 OQS03277.1 - 7e-17 61.4 0.0 8.2e-17 61.2 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 OQS03277.1 - 4.1e-05 22.3 0.0 5.6e-05 21.8 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DUF2423 PF10338.9 OQS03278.1 - 0.02 15.1 0.1 7.8 6.8 0.0 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2423) PUL PF08324.11 OQS03279.1 - 8.4e-34 117.1 5.6 1.2e-33 116.6 5.6 1.2 1 0 0 1 1 1 1 PUL domain PFU PF09070.11 OQS03279.1 - 1.8e-23 83.0 0.1 3.7e-23 82.0 0.1 1.6 1 0 0 1 1 1 1 PFU (PLAA family ubiquitin binding) WD40 PF00400.32 OQS03279.1 - 5.1e-21 74.6 17.0 4.3e-05 24.2 1.1 7.9 7 0 0 7 7 7 5 WD domain, G-beta repeat Fungal_lectin PF07938.12 OQS03279.1 - 0.0089 15.4 0.0 0.017 14.5 0.0 1.3 1 0 0 1 1 1 1 Fungal fucose-specific lectin EamA PF00892.20 OQS03280.1 - 3.2e-21 75.9 36.7 6.7e-13 49.0 15.5 2.0 2 0 0 2 2 2 2 EamA-like transporter family Multi_Drug_Res PF00893.19 OQS03280.1 - 0.32 11.7 13.3 0.33 11.6 2.8 3.3 3 1 0 3 3 3 0 Small Multidrug Resistance protein TPT PF03151.16 OQS03280.1 - 0.98 8.7 15.2 2.8 7.2 15.2 1.8 1 1 0 1 1 1 0 Triose-phosphate Transporter family PAN_4 PF14295.6 OQS03281.1 - 6.1e-43 144.5 62.0 8.3e-09 35.2 0.9 7.7 7 0 0 7 7 7 7 PAN domain PAN_1 PF00024.26 OQS03281.1 - 6.7e-34 115.7 44.5 4.7e-08 32.9 0.9 9.0 7 2 2 9 9 9 8 PAN domain PIG-L PF02585.17 OQS03281.1 - 0.0015 19.1 0.0 0.0029 18.3 0.0 1.5 1 1 0 1 1 1 1 GlcNAc-PI de-N-acetylase PAN_3 PF08277.12 OQS03281.1 - 0.014 15.2 1.1 0.014 15.2 1.1 8.0 8 0 0 8 8 8 0 PAN-like domain zinc_ribbon_12 PF11331.8 OQS03281.1 - 0.035 13.9 1.2 1.9 8.4 0.0 3.3 3 0 0 3 3 3 0 Probable zinc-ribbon domain PAN_2 PF08276.11 OQS03281.1 - 0.11 12.6 50.5 0.54 10.4 2.3 7.5 7 0 0 7 7 7 0 PAN-like domain Got1 PF04178.12 OQS03282.1 - 1.4e-28 99.6 17.7 1.4e-28 99.5 16.4 1.6 1 1 1 2 2 2 2 Got1/Sft2-like family COX15-CtaA PF02628.15 OQS03282.1 - 0.021 13.9 5.2 0.031 13.4 5.2 1.3 1 1 0 1 1 1 0 Cytochrome oxidase assembly protein Tweety PF04906.13 OQS03282.1 - 0.79 8.3 5.5 0.29 9.7 2.2 1.7 2 0 0 2 2 2 0 Tweety Glutaredoxin PF00462.24 OQS03283.1 - 2e-17 63.2 0.1 2.8e-17 62.7 0.1 1.2 1 0 0 1 1 1 1 Glutaredoxin GST_N_2 PF13409.6 OQS03283.1 - 0.0011 19.2 0.0 0.0014 18.9 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 OQS03283.1 - 0.0015 18.9 0.0 0.002 18.5 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain DUF836 PF05768.14 OQS03283.1 - 0.0031 17.9 0.0 0.0041 17.5 0.0 1.4 1 0 0 1 1 1 1 Glutaredoxin-like domain (DUF836) Thioredoxin_2 PF13098.6 OQS03283.1 - 0.02 15.4 0.0 0.025 15.0 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin-like domain DSBA PF01323.20 OQS03283.1 - 0.024 14.4 0.0 0.11 12.3 0.0 1.8 2 0 0 2 2 2 0 DSBA-like thioredoxin domain TraF PF13728.6 OQS03283.1 - 0.15 11.9 0.0 0.2 11.5 0.0 1.1 1 0 0 1 1 1 0 F plasmid transfer operon protein Ras PF00071.22 OQS03284.1 - 1.1e-65 220.1 0.3 1.6e-65 219.6 0.3 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OQS03284.1 - 7.8e-36 122.9 0.8 1.4e-35 122.1 0.2 1.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OQS03284.1 - 3.9e-16 59.0 0.1 5e-16 58.6 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 OQS03284.1 - 1.8e-06 27.7 0.2 4.6e-06 26.3 0.1 1.6 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 OQS03284.1 - 1.3e-05 24.7 0.1 1.7e-05 24.3 0.1 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 OQS03284.1 - 2.9e-05 24.1 0.0 4.9e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 OQS03284.1 - 0.00014 21.8 0.3 0.19 11.6 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase SRPRB PF09439.10 OQS03284.1 - 0.00054 19.4 0.0 0.00065 19.2 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit PduV-EutP PF10662.9 OQS03284.1 - 0.0034 17.1 0.1 0.049 13.4 0.1 2.4 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation AAA_5 PF07728.14 OQS03284.1 - 0.032 14.2 0.0 0.085 12.8 0.0 1.7 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_29 PF13555.6 OQS03284.1 - 0.039 13.7 0.3 0.11 12.3 0.0 1.8 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_16 PF13191.6 OQS03284.1 - 0.064 13.6 0.0 0.092 13.1 0.0 1.6 1 1 0 1 1 1 0 AAA ATPase domain MCM PF00493.23 OQS03284.1 - 0.1 11.7 0.0 0.28 10.3 0.0 1.6 2 0 0 2 2 2 0 MCM P-loop domain AAA_7 PF12775.7 OQS03284.1 - 0.12 11.9 0.0 0.23 11.0 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region HlyIII PF03006.20 OQS03285.1 - 1e-54 185.6 28.5 8.2e-49 166.3 21.8 2.2 2 0 0 2 2 2 2 Haemolysin-III related DUF962 PF06127.11 OQS03285.1 - 3.8 7.6 11.1 1.9 8.6 4.6 3.3 2 2 0 2 2 2 0 Protein of unknown function (DUF962) FYVE PF01363.21 OQS03286.1 - 1.7e-12 47.3 11.8 4.9e-11 42.6 8.7 2.8 2 0 0 2 2 2 1 FYVE zinc finger FYVE_2 PF02318.16 OQS03286.1 - 0.00023 21.4 6.2 0.00023 21.4 6.2 2.2 2 0 0 2 2 2 1 FYVE-type zinc finger Sigma70_ner PF04546.13 OQS03286.1 - 0.0004 20.3 1.5 0.00055 19.9 0.5 1.7 2 0 0 2 2 2 1 Sigma-70, non-essential region zf-C2HC5 PF06221.13 OQS03286.1 - 0.043 13.8 4.2 0.18 11.8 4.2 2.1 1 0 0 1 1 1 0 Putative zinc finger motif, C2HC5-type C1_2 PF03107.16 OQS03286.1 - 0.11 12.8 12.9 0.24 11.7 8.1 3.0 2 0 0 2 2 2 0 C1 domain zf-CRD PF17979.1 OQS03286.1 - 0.32 11.1 10.4 0.042 14.0 1.1 2.9 3 0 0 3 3 3 0 Cysteine rich domain with multizinc binding regions GATA PF00320.27 OQS03286.1 - 0.91 9.2 7.5 0.25 11.0 0.6 2.8 2 0 0 2 2 2 0 GATA zinc finger Zf_RING PF16744.5 OQS03286.1 - 5.7 7.1 10.1 38 4.5 0.1 3.0 2 0 0 2 2 2 0 KIAA1045 RING finger C1_1 PF00130.22 OQS03286.1 - 6.2 6.8 12.1 0.75 9.7 5.3 2.5 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-B_box PF00643.24 OQS03286.1 - 7.3 6.8 10.2 52 4.1 10.2 2.5 1 1 0 1 1 1 0 B-box zinc finger HlyIII PF03006.20 OQS03287.1 - 3.5e-48 164.3 27.4 1.1e-42 146.3 21.2 2.2 2 0 0 2 2 2 2 Haemolysin-III related Glutaredoxin PF00462.24 OQS03287.1 - 3.7e-17 62.3 0.1 7.4e-17 61.3 0.1 1.5 1 0 0 1 1 1 1 Glutaredoxin DUF836 PF05768.14 OQS03287.1 - 0.028 14.8 0.0 0.061 13.7 0.0 1.6 1 0 0 1 1 1 0 Glutaredoxin-like domain (DUF836) GST_N_2 PF13409.6 OQS03287.1 - 0.041 14.2 0.0 0.11 12.8 0.0 1.7 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 OQS03287.1 - 0.056 13.9 0.0 0.16 12.4 0.0 1.8 2 0 0 2 2 2 0 Glutathione S-transferase, N-terminal domain Thioredoxin_2 PF13098.6 OQS03287.1 - 0.11 13.0 0.0 0.23 11.9 0.0 1.5 1 0 0 1 1 1 0 Thioredoxin-like domain E1_dh PF00676.20 OQS03288.1 - 1.8e-103 345.6 0.1 2.5e-103 345.1 0.1 1.1 1 0 0 1 1 1 1 Dehydrogenase E1 component Transketolase_N PF00456.21 OQS03288.1 - 0.005 15.8 0.1 0.0072 15.3 0.1 1.3 1 1 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain DXP_synthase_N PF13292.6 OQS03288.1 - 0.011 15.0 0.1 0.041 13.1 0.0 1.9 2 1 0 2 2 2 0 1-deoxy-D-xylulose-5-phosphate synthase TPP_enzyme_C PF02775.21 OQS03288.1 - 0.017 14.9 1.4 0.017 14.9 1.4 2.2 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain DUF1451 PF07295.11 OQS03288.1 - 0.063 13.3 0.3 0.11 12.6 0.3 1.2 1 0 0 1 1 1 0 Zinc-ribbon containing domain Myosin_head PF00063.21 OQS03289.1 - 8.6e-97 325.0 7.1 3.9e-96 322.8 7.1 1.8 1 1 0 1 1 1 1 Myosin head (motor domain) MyTH4 PF00784.17 OQS03289.1 - 1.7e-13 51.0 0.3 1.5e-12 48.0 0.0 2.8 3 0 0 3 3 3 1 MyTH4 domain GYF_2 PF14237.6 OQS03289.1 - 5.3e-10 38.9 0.4 1.1e-09 37.9 0.4 1.6 1 0 0 1 1 1 1 GYF domain 2 SH3_9 PF14604.6 OQS03289.1 - 0.00014 21.7 0.1 0.00033 20.4 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_3 PF08239.11 OQS03289.1 - 0.00024 21.3 0.2 0.00059 20.1 0.2 1.7 1 0 0 1 1 1 1 Bacterial SH3 domain RNA_helicase PF00910.22 OQS03289.1 - 0.0006 20.2 0.1 0.003 17.9 0.1 2.3 2 0 0 2 2 2 1 RNA helicase ATPase_2 PF01637.18 OQS03289.1 - 0.0048 16.9 0.1 1.2 9.0 0.0 2.6 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea GYF PF02213.16 OQS03289.1 - 0.0068 16.0 0.2 0.014 15.0 0.2 1.6 1 0 0 1 1 1 1 GYF domain AAA_22 PF13401.6 OQS03289.1 - 0.0074 16.6 2.4 0.032 14.5 0.0 3.2 3 1 0 3 3 3 1 AAA domain AAA_7 PF12775.7 OQS03289.1 - 0.053 13.0 0.1 0.17 11.4 0.0 1.9 2 0 0 2 2 2 0 P-loop containing dynein motor region FTA4 PF13093.6 OQS03289.1 - 0.075 12.9 1.5 0.18 11.7 1.5 1.6 1 0 0 1 1 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 ABC_tran PF00005.27 OQS03289.1 - 0.08 13.5 0.3 0.44 11.1 0.0 2.3 2 0 0 2 2 2 0 ABC transporter AAA_19 PF13245.6 OQS03289.1 - 0.09 13.1 0.0 0.56 10.5 0.0 2.4 2 0 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 OQS03289.1 - 0.1 12.5 0.1 0.22 11.4 0.1 1.5 1 0 0 1 1 1 0 RsgA GTPase AAA_33 PF13671.6 OQS03289.1 - 0.1 12.7 0.0 0.25 11.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain Glyco_hydro_72 PF03198.14 OQS03290.1 - 7.5e-35 120.7 3.5 6.1e-21 75.0 0.6 2.4 1 1 1 2 2 2 2 Glucanosyltransferase ABC_membrane PF00664.23 OQS03291.1 - 6.4e-104 347.4 25.7 8.6e-57 192.9 7.1 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 OQS03291.1 - 2.5e-48 164.1 0.0 5.8e-35 120.8 0.0 2.4 2 0 0 2 2 2 2 ABC transporter AAA_29 PF13555.6 OQS03291.1 - 2.1e-07 30.5 0.9 0.025 14.3 0.2 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain Zeta_toxin PF06414.12 OQS03291.1 - 2.6e-07 30.1 0.0 0.0067 15.7 0.0 2.3 2 0 0 2 2 2 2 Zeta toxin SMC_N PF02463.19 OQS03291.1 - 1.5e-06 27.8 1.4 0.00076 19.0 0.0 3.1 2 1 1 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 OQS03291.1 - 3e-06 27.5 0.1 0.022 15.0 0.0 3.1 2 1 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 OQS03291.1 - 1.3e-05 25.2 0.0 0.14 12.0 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase G-alpha PF00503.20 OQS03291.1 - 1.4e-05 24.4 0.0 0.073 12.2 0.0 2.2 2 0 0 2 2 2 2 G-protein alpha subunit AAA_16 PF13191.6 OQS03291.1 - 1.5e-05 25.4 0.1 0.091 13.1 0.0 2.7 2 0 0 2 2 2 2 AAA ATPase domain AAA_15 PF13175.6 OQS03291.1 - 0.00014 21.7 0.0 0.31 10.7 0.0 2.2 2 0 0 2 2 2 2 AAA ATPase domain APS_kinase PF01583.20 OQS03291.1 - 0.00022 21.1 0.2 0.37 10.7 0.0 2.4 2 0 0 2 2 2 2 Adenylylsulphate kinase DUF87 PF01935.17 OQS03291.1 - 0.00023 21.3 0.3 0.3 11.1 0.0 2.5 2 0 0 2 2 2 2 Helicase HerA, central domain AAA_30 PF13604.6 OQS03291.1 - 0.00039 20.2 0.4 0.42 10.3 0.1 3.0 2 1 0 2 2 2 2 AAA domain AAA_24 PF13479.6 OQS03291.1 - 0.0017 18.1 0.0 0.37 10.5 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 OQS03291.1 - 0.0018 17.9 0.3 0.27 10.8 0.0 2.9 3 0 0 3 3 3 1 AAA domain AAA_7 PF12775.7 OQS03291.1 - 0.0031 17.1 0.0 1.1 8.7 0.0 2.5 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_28 PF13521.6 OQS03291.1 - 0.0075 16.5 0.4 2.2 8.5 0.1 2.4 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.6 OQS03291.1 - 0.018 14.9 0.4 4.7 6.9 0.0 2.6 3 0 0 3 3 3 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_18 PF13238.6 OQS03291.1 - 0.019 15.5 0.0 0.92 10.1 0.0 2.5 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 OQS03291.1 - 0.02 14.9 0.2 7.5 6.7 0.0 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_33 PF13671.6 OQS03291.1 - 0.026 14.7 0.0 3 8.0 0.0 2.5 2 0 0 2 2 2 0 AAA domain Pox_A32 PF04665.12 OQS03291.1 - 0.032 13.7 0.5 10 5.5 0.0 2.8 3 0 0 3 3 3 0 Poxvirus A32 protein FtsK_SpoIIIE PF01580.18 OQS03291.1 - 0.033 13.6 0.2 5.1 6.4 0.0 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_5 PF07728.14 OQS03291.1 - 0.049 13.6 0.1 3.1 7.8 0.0 2.8 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) PRK PF00485.18 OQS03291.1 - 0.065 13.0 0.0 3.7 7.2 0.0 2.3 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family ATP-synt_ab PF00006.25 OQS03291.1 - 0.13 11.9 0.0 12 5.4 0.0 2.5 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_23 PF13476.6 OQS03291.1 - 0.24 11.9 1.7 20 5.6 0.1 2.3 2 0 0 2 2 2 0 AAA domain Sugar_tr PF00083.24 OQS03292.1 - 4.5e-15 55.5 2.9 4.9e-15 55.3 2.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OQS03292.1 - 0.00059 18.9 0.5 0.00062 18.8 0.5 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF3439 PF11921.8 OQS03293.1 - 3.7 7.5 16.9 0.05 13.6 4.0 2.8 1 1 2 3 3 3 0 Domain of unknown function (DUF3439) Peptidase_C1 PF00112.23 OQS03294.1 - 3.3e-54 184.3 2.7 7.7e-54 183.1 2.7 1.7 1 0 0 1 1 1 1 Papain family cysteine protease Ricin_B_lectin PF00652.22 OQS03294.1 - 4.7e-28 98.0 20.8 2.3e-15 56.9 5.6 3.7 3 1 0 3 3 3 2 Ricin-type beta-trefoil lectin domain CDtoxinA PF03498.14 OQS03294.1 - 1.5e-06 27.9 1.3 0.047 13.3 0.1 2.7 2 0 0 2 2 2 2 Cytolethal distending toxin A/C domain Cys_box PF17869.1 OQS03294.1 - 0.015 15.4 1.7 0.19 11.9 0.2 2.7 2 0 0 2 2 2 0 Anosmin cysteine rich domain Inhibitor_I29 PF08246.12 OQS03294.1 - 0.15 12.5 0.7 0.46 11.0 0.7 1.9 1 0 0 1 1 1 0 Cathepsin propeptide inhibitor domain (I29) Cep57_CLD PF14073.6 OQS03295.1 - 1e-07 32.2 31.6 1e-07 32.2 31.6 3.3 4 0 0 4 4 4 1 Centrosome localisation domain of Cep57 Cep57_MT_bd PF06657.13 OQS03295.1 - 6.6e-05 23.3 2.0 6.6e-05 23.3 2.0 5.1 3 1 3 6 6 6 1 Centrosome microtubule-binding domain of Cep57 ATG16 PF08614.11 OQS03295.1 - 0.0054 17.0 23.1 0.0054 17.0 23.1 4.3 1 1 2 4 4 4 2 Autophagy protein 16 (ATG16) TMF_TATA_bd PF12325.8 OQS03295.1 - 0.037 14.3 0.9 0.037 14.3 0.9 6.1 3 2 3 6 6 6 0 TATA element modulatory factor 1 TATA binding Filament PF00038.21 OQS03295.1 - 2.6 7.5 44.2 1 8.9 6.9 4.4 2 2 1 3 3 3 0 Intermediate filament protein APG6_N PF17675.1 OQS03295.1 - 8.4 6.9 62.0 4.1 7.9 4.4 5.8 3 1 1 4 4 4 0 Apg6 coiled-coil region PPR_long PF17177.4 OQS03296.1 - 1.2e-11 44.4 3.1 3e-06 26.8 0.3 3.4 3 1 1 4 4 4 3 Pentacotripeptide-repeat region of PRORP PPR_2 PF13041.6 OQS03296.1 - 6e-10 39.2 1.3 0.00027 21.1 0.1 4.1 4 0 0 4 4 4 2 PPR repeat family PPR PF01535.20 OQS03296.1 - 5.4e-07 29.4 0.7 0.47 10.8 0.0 4.6 4 0 0 4 4 4 2 PPR repeat Rep_fac_C PF08542.11 OQS03296.1 - 0.18 12.2 0.4 1.1 9.7 0.0 2.5 3 0 0 3 3 3 0 Replication factor C C-terminal domain Kinesin PF00225.23 OQS03297.1 - 7e-91 304.6 1.5 1.5e-90 303.6 1.5 1.4 1 1 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 OQS03297.1 - 1.6e-25 89.8 0.0 3.7e-25 88.6 0.0 1.6 1 0 0 1 1 1 1 Microtubule binding ABC_tran_CTD PF16326.5 OQS03297.1 - 0.077 13.3 0.2 0.2 11.9 0.2 1.7 1 0 0 1 1 1 0 ABC transporter C-terminal domain Herpes_BLRF2 PF05812.12 OQS03297.1 - 0.12 12.5 0.2 0.12 12.5 0.2 1.9 2 0 0 2 2 2 0 Herpesvirus BLRF2 protein DUF1843 PF08898.10 OQS03297.1 - 0.34 11.4 1.0 0.71 10.4 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1843) Lzipper-MIP1 PF14389.6 OQS03297.1 - 2.4 8.5 4.4 2.1 8.7 0.5 2.6 2 1 1 3 3 3 0 Leucine-zipper of ternary complex factor MIP1 RabGAP-TBC PF00566.18 OQS03298.1 - 4.7e-35 121.2 0.0 7.7e-35 120.5 0.0 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain PH PF00169.29 OQS03298.1 - 4.6e-13 49.6 0.1 8.4e-13 48.8 0.1 1.4 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 OQS03298.1 - 7.3e-05 23.1 0.1 0.0015 18.9 0.1 2.3 1 1 0 1 1 1 1 Pleckstrin homology domain PH_8 PF15409.6 OQS03298.1 - 0.012 15.8 0.0 0.035 14.4 0.0 1.8 1 1 0 1 1 1 0 Pleckstrin homology domain Ecm29 PF13001.7 OQS03299.1 - 2.6e-55 188.0 0.4 2.6e-55 188.0 0.4 2.7 2 1 1 3 3 3 1 Proteasome stabiliser HEAT PF02985.22 OQS03299.1 - 4.1e-08 32.8 7.2 0.12 12.7 0.0 8.1 8 0 0 8 8 8 2 HEAT repeat Vac14_Fab1_bd PF12755.7 OQS03299.1 - 0.00083 19.9 1.5 0.0047 17.5 0.2 3.1 2 0 0 2 2 2 1 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.6 OQS03299.1 - 0.028 14.9 1.2 5.1 7.7 0.0 4.8 4 0 0 4 4 4 0 HEAT-like repeat Rota_NS6 PF04866.12 OQS03299.1 - 0.079 13.2 0.3 0.42 10.8 0.2 2.4 1 1 0 1 1 1 0 Rotavirus non-structural protein 6 FHA PF00498.26 OQS03300.1 - 1.7e-12 47.5 0.2 3.5e-12 46.5 0.2 1.6 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 OQS03300.1 - 3.5e-06 27.2 0.8 9.2e-06 25.9 0.0 2.1 2 0 0 2 2 2 1 Inner membrane component of T3SS, cytoplasmic domain CM_2 PF01817.21 OQS03300.1 - 0.032 14.6 0.2 0.11 12.9 0.0 2.0 2 0 0 2 2 2 0 Chorismate mutase type II FHA_2 PF17913.1 OQS03300.1 - 0.055 13.7 0.0 0.16 12.2 0.0 1.8 1 0 0 1 1 1 0 FHA domain Glyco_hydro_32C PF08244.12 OQS03300.1 - 0.081 12.9 1.0 0.17 11.8 0.0 2.0 3 0 0 3 3 3 0 Glycosyl hydrolases family 32 C terminal APG6_N PF17675.1 OQS03300.1 - 0.14 12.7 9.6 1.1 9.8 4.2 2.3 2 0 0 2 2 2 0 Apg6 coiled-coil region Frankia_peptide PF14407.6 OQS03300.1 - 0.18 11.8 1.0 0.42 10.6 1.0 1.6 1 0 0 1 1 1 0 Ribosomally synthesized peptide prototyped by Frankia Franean1_4349. Osmo_CC PF08946.10 OQS03300.1 - 0.25 11.6 2.7 0.68 10.2 0.4 2.5 2 0 0 2 2 2 0 Osmosensory transporter coiled coil Tup_N PF08581.10 OQS03300.1 - 1.9 8.8 5.7 3.7 7.9 1.5 2.5 2 0 0 2 2 2 0 Tup N-terminal UPF0489 PF12640.7 OQS03301.1 - 1.6e-43 149.0 0.1 2.9e-43 148.2 0.1 1.4 1 0 0 1 1 1 1 UPF0489 domain Arginase PF00491.21 OQS03301.1 - 0.0065 16.0 0.6 0.01 15.4 0.6 1.2 1 0 0 1 1 1 1 Arginase family Vfa1 PF08432.10 OQS03302.1 - 0.008 16.5 5.0 0.0093 16.3 5.0 1.1 1 0 0 1 1 1 1 AAA-ATPase Vps4-associated protein 1 SLATT_fungal PF18142.1 OQS03302.1 - 0.02 14.8 0.6 0.029 14.4 0.6 1.2 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain CRF PF00473.17 OQS03302.1 - 0.051 13.6 1.4 0.092 12.8 1.4 1.4 1 0 0 1 1 1 0 Corticotropin-releasing factor family WDCP PF15390.6 OQS03302.1 - 0.19 10.0 3.1 0.2 10.0 3.1 1.0 1 0 0 1 1 1 0 WD repeat and coiled-coil-containing protein family MFS_1 PF07690.16 OQS03304.1 - 2.9e-13 49.5 43.7 6.8e-07 28.5 16.8 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 OQS03304.1 - 9.8e-12 44.1 11.8 9.8e-12 44.1 11.8 2.7 2 1 1 3 3 3 1 MFS/sugar transport protein TssO PF17561.2 OQS03304.1 - 6.8 6.8 6.2 0.68 10.0 1.1 2.0 2 0 0 2 2 2 0 Type VI secretion system, TssO Dehydratase_SU PF02287.15 OQS03305.1 - 0.03 14.4 0.9 0.045 13.8 0.2 1.6 2 0 0 2 2 2 0 Dehydratase small subunit Ank_4 PF13637.6 OQS03306.1 - 1.5e-11 44.6 0.3 1.8e-06 28.3 0.1 2.1 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 OQS03306.1 - 6.4e-07 29.5 0.0 0.0061 16.8 0.1 2.1 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 OQS03306.1 - 9.2e-07 29.4 0.1 1.2e-06 29.1 0.1 1.2 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OQS03306.1 - 6.8e-06 26.0 0.0 0.13 12.9 0.0 2.2 2 0 0 2 2 2 2 Ankyrin repeat DUF5049 PF16468.5 OQS03306.1 - 0.00029 20.7 0.3 0.37 10.7 0.0 2.1 1 1 1 2 2 2 2 Domain of unknown function (DUF5049) FAM195 PF14799.6 OQS03306.1 - 0.053 13.9 0.1 2.9 8.3 0.0 2.1 1 1 1 2 2 2 0 FAM195 family Prenyltrans PF00432.21 OQS03307.1 - 1.4e-27 95.1 7.1 4e-07 29.6 0.0 5.2 5 0 0 5 5 5 5 Prenyltransferase and squalene oxidase repeat Band_7 PF01145.25 OQS03308.1 - 1e-29 103.8 3.9 2.6e-29 102.5 0.0 2.5 3 0 0 3 3 3 1 SPFH domain / Band 7 family Band_7_C PF16200.5 OQS03308.1 - 4.7e-26 90.6 2.1 1.4e-25 89.1 2.1 1.9 1 0 0 1 1 1 1 C-terminal region of band_7 Glyco_transf_28 PF03033.20 OQS03308.1 - 2.3e-12 47.1 0.2 1.3e-11 44.7 0.0 2.3 3 0 0 3 3 3 1 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.18 OQS03308.1 - 0.0012 17.7 0.0 0.0021 17.0 0.0 1.3 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase DUF4938 PF16292.5 OQS03308.1 - 0.02 14.2 0.4 0.036 13.4 0.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4938) Band_7_1 PF13421.6 OQS03308.1 - 0.13 11.9 0.3 0.66 9.6 0.0 2.1 2 0 0 2 2 2 0 SPFH domain-Band 7 family Bactofilin PF04519.13 OQS03309.1 - 4.1e-18 65.5 0.2 5.3e-18 65.1 0.2 1.2 1 0 0 1 1 1 1 Polymer-forming cytoskeletal Ank_2 PF12796.7 OQS03310.1 - 2.3e-130 425.4 9.1 2.8e-15 56.7 0.0 9.6 2 2 10 12 12 12 12 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQS03310.1 - 5.6e-90 294.6 4.5 3.2e-09 37.1 0.0 13.4 4 4 11 15 15 15 15 Ankyrin repeats (many copies) Ank PF00023.30 OQS03310.1 - 6.8e-84 273.0 23.9 1.2e-06 28.7 0.0 17.8 20 0 0 20 20 20 14 Ankyrin repeat Ank_3 PF13606.6 OQS03310.1 - 8.1e-78 247.0 9.5 0.00019 21.6 0.0 18.3 18 0 0 18 18 18 15 Ankyrin repeat Ank_5 PF13857.6 OQS03310.1 - 1.9e-69 228.8 16.0 2.3e-08 34.1 0.0 12.5 4 2 9 13 13 13 13 Ankyrin repeats (many copies) Pkinase_Tyr PF07714.17 OQS03310.1 - 1.8e-43 148.7 0.0 9.9e-43 146.3 0.0 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.25 OQS03310.1 - 5.8e-40 137.3 0.0 1.4e-39 136.1 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_fungal PF17667.1 OQS03310.1 - 0.00064 18.6 0.0 0.0031 16.3 0.0 2.0 2 0 0 2 2 2 1 Fungal protein kinase Haspin_kinase PF12330.8 OQS03310.1 - 0.0015 17.5 0.1 0.0026 16.8 0.1 1.3 1 0 0 1 1 1 1 Haspin like kinase domain DUF2520 PF10728.9 OQS03310.1 - 0.13 12.0 4.2 6.9 6.5 0.2 3.5 1 1 1 2 2 2 0 Domain of unknown function (DUF2520) DUF1336 PF07059.12 OQS03311.1 - 9.2e-51 173.1 0.0 1.4e-50 172.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1336) PH PF00169.29 OQS03311.1 - 8.3e-09 35.9 0.3 2.6e-08 34.3 0.3 1.9 1 1 0 1 1 1 1 PH domain PH_8 PF15409.6 OQS03311.1 - 0.0012 19.1 0.0 0.12 12.7 0.0 2.5 2 0 0 2 2 2 1 Pleckstrin homology domain PH_11 PF15413.6 OQS03311.1 - 0.0079 16.6 1.0 0.029 14.8 1.0 2.1 1 1 0 1 1 1 1 Pleckstrin homology domain Stm1_N PF09598.10 OQS03311.1 - 0.011 16.5 1.4 0.041 14.7 1.4 1.9 1 0 0 1 1 1 0 Stm1 GbpA_2 PF18416.1 OQS03311.1 - 0.16 12.3 0.8 3.3 8.0 0.3 2.5 2 0 0 2 2 2 0 N-acetylglucosamine binding protein domain 2 SPX PF03105.19 OQS03312.1 - 5.8e-13 49.5 0.8 1.9e-07 31.3 0.0 2.2 2 0 0 2 2 2 2 SPX domain GDPD PF03009.17 OQS03312.1 - 2e-09 37.6 0.0 4.4e-05 23.3 0.0 2.4 2 0 0 2 2 2 2 Glycerophosphoryl diester phosphodiesterase family zf-C3HC4_4 PF15227.6 OQS03312.1 - 6.1e-08 32.7 11.6 1.9e-07 31.1 11.6 1.9 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.6 OQS03312.1 - 9.6e-08 31.9 9.5 1.1e-07 31.7 8.0 1.9 1 1 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 OQS03312.1 - 1.9e-06 27.6 14.1 6.3e-06 26.0 14.1 2.0 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 OQS03312.1 - 4.8e-06 26.3 13.7 1.4e-05 24.8 13.7 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 OQS03312.1 - 8e-06 25.6 17.6 2.7e-05 23.9 17.6 2.0 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 OQS03312.1 - 8.4e-06 26.0 17.3 8.4e-06 26.0 17.3 2.3 2 0 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.6 OQS03312.1 - 0.00094 19.1 16.1 0.00094 19.1 16.1 2.0 2 0 0 2 2 1 1 zinc-RING finger domain zf-RING_4 PF14570.6 OQS03312.1 - 0.0066 16.2 3.7 0.0066 16.2 3.7 2.3 2 0 0 2 2 2 1 RING/Ubox like zinc-binding domain Prok-RING_4 PF14447.6 OQS03312.1 - 0.063 13.2 18.6 0.063 13.1 13.7 2.8 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 zf-RING_10 PF16685.5 OQS03312.1 - 0.44 10.7 7.3 1.5 9.1 7.3 1.9 1 0 0 1 1 1 0 zinc RING finger of MSL2 FYVE_2 PF02318.16 OQS03312.1 - 0.53 10.5 3.4 2.1 8.6 3.4 2.0 1 0 0 1 1 1 0 FYVE-type zinc finger zf-Nse PF11789.8 OQS03312.1 - 1.7 8.5 9.6 3.9 7.4 9.6 1.6 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Ank_2 PF12796.7 OQS03313.1 - 1.8e-45 153.5 12.2 2e-11 44.3 0.2 5.6 2 2 4 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQS03313.1 - 7.3e-42 141.2 1.2 7.4e-08 32.8 0.1 9.2 2 2 7 9 9 9 9 Ankyrin repeats (many copies) Pkinase PF00069.25 OQS03313.1 - 1.7e-41 142.4 0.0 2.6e-41 141.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Ank_5 PF13857.6 OQS03313.1 - 8.8e-40 134.3 1.2 7.8e-08 32.4 0.1 7.4 5 2 2 7 7 7 7 Ankyrin repeats (many copies) Pkinase_Tyr PF07714.17 OQS03313.1 - 6.5e-39 133.8 0.0 1.6e-38 132.5 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Ank PF00023.30 OQS03313.1 - 2.7e-25 87.7 15.0 5.5e-08 32.9 0.0 9.4 9 1 0 9 9 9 5 Ankyrin repeat Ank_3 PF13606.6 OQS03313.1 - 6.3e-23 78.4 11.0 0.00014 22.0 0.0 10.4 11 0 0 11 11 11 5 Ankyrin repeat YfmQ PF10787.9 OQS03313.1 - 0.00098 18.9 0.0 2.3 8.0 0.0 3.9 4 0 0 4 4 4 1 Uncharacterised protein from bacillus cereus group Chlam_OMP6 PF03504.13 OQS03313.1 - 0.15 12.4 0.0 0.33 11.3 0.0 1.6 1 0 0 1 1 1 0 Chlamydia cysteine-rich outer membrane protein 6 BaxI_1 PF12811.7 OQS03314.1 - 1.4 8.4 21.2 0.68 9.5 19.1 1.5 1 1 0 1 1 1 0 Bax inhibitor 1 like Rad60-SLD PF11976.8 OQS03315.1 - 1.7e-17 63.0 0.1 2.1e-17 62.7 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 OQS03315.1 - 3.4e-10 39.5 0.0 4.1e-10 39.3 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin family MFS_1 PF07690.16 OQS03316.1 - 3.4e-09 36.1 33.6 2.7e-07 29.9 14.6 2.7 1 1 1 2 2 2 2 Major Facilitator Superfamily Y_phosphatase2 PF03162.13 OQS03317.1 - 1.1e-48 164.9 0.0 1.3e-48 164.7 0.0 1.0 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.6 OQS03317.1 - 5.8e-06 26.4 0.0 8e-06 26.0 0.0 1.3 1 1 0 1 1 1 1 Tyrosine phosphatase family TrmO PF01980.16 OQS03318.1 - 2.2e-33 115.0 0.0 5.9e-33 113.6 0.0 1.7 1 0 0 1 1 1 1 tRNA-methyltransferase O Rrp15p PF07890.12 OQS03318.1 - 2.1e-17 63.7 11.1 2.1e-17 63.7 11.1 3.3 2 1 1 3 3 3 1 Rrp15p TrmO_C PF18389.1 OQS03318.1 - 0.0052 16.9 0.1 0.013 15.6 0.1 1.7 1 0 0 1 1 1 1 TrmO C-terminal domain IBR PF01485.21 OQS03320.1 - 0.00049 20.3 10.5 0.00049 20.3 10.5 3.8 1 1 3 4 4 4 2 IBR domain, a half RING-finger domain zf-B_box PF00643.24 OQS03320.1 - 0.021 15.0 9.9 0.021 15.0 9.9 5.5 5 1 1 6 6 6 0 B-box zinc finger CcmD PF04995.14 OQS03320.1 - 8.1 6.6 7.0 0.75 9.9 1.4 2.1 2 0 0 2 2 2 0 Heme exporter protein D (CcmD) Cpn60_TCP1 PF00118.24 OQS03321.1 - 8.4e-169 562.3 1.9 9.5e-169 562.1 1.9 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Piezo_RRas_bdg PF12166.8 OQS03321.1 - 0.032 13.5 0.0 0.044 13.1 0.0 1.1 1 0 0 1 1 1 0 Piezo non-specific cation channel, R-Ras-binding domain WD40 PF00400.32 OQS03322.1 - 2.9e-15 56.4 5.5 0.00038 21.2 0.0 5.4 5 0 0 5 5 5 4 WD domain, G-beta repeat BBS2_Mid PF14783.6 OQS03322.1 - 0.00022 21.2 0.7 1.1 9.3 0.0 3.8 3 1 1 4 4 4 3 Ciliary BBSome complex subunit 2, middle region PQ-loop PF04193.14 OQS03323.1 - 0.12 12.2 0.1 0.24 11.2 0.1 1.4 1 0 0 1 1 1 0 PQ loop repeat DSPc PF00782.20 OQS03324.1 - 1.4e-43 147.9 0.5 7.6e-25 87.3 0.1 2.5 2 0 0 2 2 2 2 Dual specificity phosphatase, catalytic domain FYVE PF01363.21 OQS03324.1 - 2.3e-09 37.2 17.3 4e-09 36.5 16.3 1.9 2 0 0 2 2 2 1 FYVE zinc finger Rhodanese PF00581.20 OQS03324.1 - 4.8e-06 27.0 0.0 4.7e-05 23.9 0.0 2.6 2 0 0 2 2 2 1 Rhodanese-like domain Y_phosphatase PF00102.27 OQS03324.1 - 5.5e-06 26.1 0.0 0.0041 16.7 0.0 2.7 2 1 1 3 3 3 2 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 OQS03324.1 - 0.0024 18.0 0.0 2.6 8.2 0.0 2.7 2 0 0 2 2 2 2 Inositol hexakisphosphate Init_tRNA_PT PF04179.12 OQS03324.1 - 0.039 14.3 0.0 8.6 6.7 0.0 2.6 2 0 0 2 2 2 0 Rit1 DUSP-like domain Nab1 PF04902.12 OQS03324.1 - 0.053 13.9 0.7 0.097 13.1 0.7 1.4 1 0 0 1 1 1 0 Conserved region in Nab1 FYVE_2 PF02318.16 OQS03324.1 - 0.33 11.2 11.7 0.9 9.8 11.7 1.7 1 0 0 1 1 1 0 FYVE-type zinc finger RRM_1 PF00076.22 OQS03325.1 - 3.1e-08 33.3 0.0 4.6e-05 23.2 0.0 2.5 1 1 1 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 OQS03325.1 - 0.1 12.5 0.0 0.59 10.0 0.0 2.1 2 0 0 2 2 2 0 Occluded RNA-recognition motif DUF1727 PF08353.10 OQS03325.1 - 0.16 11.9 1.3 0.25 11.3 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1727) DPBB_1 PF03330.18 OQS03326.1 - 3.1e-06 27.4 0.0 2e-05 24.8 0.0 2.4 2 0 0 2 2 2 1 Lytic transglycolase DUF5326 PF17260.2 OQS03326.1 - 0.014 15.6 0.2 0.087 13.0 0.1 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5326) DUF5305 PF17231.2 OQS03326.1 - 0.21 11.0 0.1 0.21 11.0 0.1 2.3 3 0 0 3 3 3 0 Family of unknown function (DUF5305) Ras PF00071.22 OQS03327.1 - 3.7e-52 176.2 0.1 4.6e-52 175.9 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OQS03327.1 - 1e-33 116.1 0.0 1.7e-33 115.4 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OQS03327.1 - 4.8e-14 52.2 0.3 5.7e-14 51.9 0.3 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 OQS03327.1 - 7.1e-07 28.8 0.0 9.4e-07 28.4 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 OQS03327.1 - 0.0002 21.0 0.1 0.00032 20.3 0.1 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 OQS03327.1 - 0.00036 20.0 0.0 0.00076 19.0 0.0 1.5 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 OQS03327.1 - 0.001 19.2 0.0 0.0019 18.3 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_14 PF13173.6 OQS03327.1 - 0.002 18.1 0.2 0.0075 16.3 0.2 1.8 1 1 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 OQS03327.1 - 0.017 15.1 0.0 0.81 9.6 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase P_C PF06640.11 OQS03327.1 - 3.1 7.9 6.6 0.62 10.2 3.2 1.5 2 0 0 2 2 2 0 P protein C-terminus PetL PF05115.14 OQS03328.1 - 0.015 15.2 0.0 0.037 14.0 0.0 1.6 1 0 0 1 1 1 0 Cytochrome B6-F complex subunit VI (PetL) DUF2867 PF11066.8 OQS03328.1 - 0.066 13.5 0.1 0.1 13.0 0.1 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2867) PDZ_6 PF17820.1 OQS03329.1 - 4e-13 49.0 0.1 1.3e-05 24.9 0.0 4.1 4 0 0 4 4 4 3 PDZ domain PDZ PF00595.24 OQS03329.1 - 1.8e-10 41.0 0.0 2.3e-06 27.9 0.0 3.5 3 0 0 3 3 3 2 PDZ domain MSA-2c PF12238.8 OQS03329.1 - 0.0054 16.8 2.1 0.0054 16.8 2.1 2.4 3 0 0 3 3 3 1 Merozoite surface antigen 2c zf-RRN7 PF11781.8 OQS03329.1 - 3 7.6 8.0 8.8 6.1 8.0 1.7 1 1 0 1 1 1 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 IQ PF00612.27 OQS03330.1 - 0.00051 19.6 0.6 0.0017 18.0 0.6 1.9 1 0 0 1 1 1 1 IQ calmodulin-binding motif MIT PF04212.18 OQS03331.1 - 1.1e-08 35.0 0.1 3.1e-08 33.6 0.0 1.8 2 0 0 2 2 2 1 MIT (microtubule interacting and transport) domain TPR_11 PF13414.6 OQS03331.1 - 0.076 12.7 0.2 0.15 11.8 0.2 1.4 1 0 0 1 1 1 0 TPR repeat P2_N PF18628.1 OQS03331.1 - 0.098 12.4 0.0 0.29 10.9 0.0 1.7 2 0 0 2 2 2 0 Viral coat protein P2 N-terminal domain TPR_1 PF00515.28 OQS03331.1 - 0.23 11.4 1.1 0.38 10.7 0.1 1.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.17 OQS03331.1 - 0.44 10.8 3.2 0.64 10.3 0.3 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat zf-C2H2_8 PF15909.5 OQS03332.1 - 0.011 16.0 1.1 1.1 9.6 0.0 2.3 2 1 0 2 2 2 0 C2H2-type zinc ribbon Glutaredoxin2_C PF04399.13 OQS03333.1 - 2.3e-46 156.8 0.0 3e-46 156.5 0.0 1.1 1 0 0 1 1 1 1 Glutaredoxin 2, C terminal domain GST_N_3 PF13417.6 OQS03333.1 - 3.5e-11 43.3 0.0 6.8e-11 42.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 OQS03333.1 - 5.9e-08 32.9 0.0 1.5e-07 31.6 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain Glutaredoxin PF00462.24 OQS03333.1 - 0.0095 16.1 0.0 0.031 14.5 0.0 1.8 1 0 0 1 1 1 1 Glutaredoxin GST_C_3 PF14497.6 OQS03333.1 - 0.011 15.9 0.1 0.047 13.9 0.1 1.9 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain 2OG-FeII_Oxy_3 PF13640.6 OQS03334.1 - 4e-14 53.3 0.0 1e-13 52.0 0.0 1.7 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily SIN1_PH PF16979.5 OQS03334.1 - 0.074 13.3 0.0 0.17 12.1 0.0 1.6 1 0 0 1 1 1 0 SAPK-interacting protein 1 (Sin1), Pleckstrin-homology VHL PF01847.16 OQS03334.1 - 0.09 12.7 0.0 0.22 11.4 0.0 1.6 1 0 0 1 1 1 0 VHL beta domain WD40 PF00400.32 OQS03335.1 - 7.1e-08 33.0 16.8 0.054 14.4 0.7 6.7 7 0 0 7 7 7 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OQS03335.1 - 7.1e-06 26.2 0.7 0.064 13.6 0.1 4.1 4 1 1 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 OQS03335.1 - 3.9e-05 22.5 0.2 8.8e-05 21.3 0.2 1.5 1 0 0 1 1 1 1 Nucleoporin Nup120/160 SNF2_N PF00176.23 OQS03336.1 - 2.9e-46 157.8 0.5 5.1e-46 157.0 0.1 1.6 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 OQS03336.1 - 2e-16 60.3 0.0 1.9e-15 57.1 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ERCC3_RAD25_C PF16203.5 OQS03336.1 - 1.9e-05 24.0 0.1 0.11 11.7 0.0 2.5 2 0 0 2 2 2 2 ERCC3/RAD25/XPB C-terminal helicase Helicase_C_2 PF13307.6 OQS03336.1 - 0.0021 18.3 0.1 0.0081 16.3 0.0 2.1 3 0 0 3 3 3 1 Helicase C-terminal domain DDE_Tnp_1_7 PF13843.6 OQS03336.1 - 0.074 12.3 0.0 0.28 10.5 0.0 1.9 2 0 0 2 2 2 0 Transposase IS4 DEAD PF00270.29 OQS03336.1 - 0.089 12.6 0.0 0.35 10.6 0.0 1.9 2 0 0 2 2 2 0 DEAD/DEAH box helicase CLPTM1 PF05602.12 OQS03337.1 - 5.7e-130 434.2 0.7 5.7e-130 434.2 0.7 1.5 2 0 0 2 2 2 1 Cleft lip and palate transmembrane protein 1 (CLPTM1) Glyco_transf_8 PF01501.20 OQS03337.1 - 0.0059 16.2 0.6 0.014 14.9 0.1 1.8 2 0 0 2 2 2 1 Glycosyl transferase family 8 Bap31 PF05529.12 OQS03337.1 - 0.026 14.4 4.7 4.3 7.2 0.0 2.6 2 0 0 2 2 2 0 Bap31/Bap29 transmembrane region TMEM208_SND2 PF05620.11 OQS03337.1 - 0.034 13.9 0.1 0.034 13.9 0.1 2.9 2 1 1 3 3 3 0 SRP-independent targeting protein 2/TMEM208 PQ-loop PF04193.14 OQS03337.1 - 0.038 13.8 0.3 0.038 13.8 0.3 2.8 3 0 0 3 3 3 0 PQ loop repeat Mannosyl_trans3 PF11051.8 OQS03337.1 - 0.048 13.0 0.0 0.087 12.2 0.0 1.4 1 0 0 1 1 1 0 Mannosyltransferase putative Sec6 PF06046.13 OQS03338.1 - 3.1e-32 111.7 9.3 4.9e-32 111.0 9.3 1.3 1 0 0 1 1 1 1 Exocyst complex component Sec6 Cdh1_DBD_1 PF18196.1 OQS03338.1 - 0.81 10.0 6.4 0.25 11.7 1.7 2.4 2 0 0 2 2 2 0 Chromodomain helicase DNA-binding domain 1 SNAP PF14938.6 OQS03339.1 - 1.2e-20 74.1 15.0 1.2e-20 74.1 15.0 1.8 2 0 0 2 2 2 1 Soluble NSF attachment protein, SNAP TPR_12 PF13424.6 OQS03339.1 - 8.9e-11 41.9 7.5 0.0016 18.6 0.2 4.5 3 1 1 4 4 4 4 Tetratricopeptide repeat TPR_2 PF07719.17 OQS03339.1 - 5.5e-09 35.5 10.5 0.00011 22.0 0.0 5.6 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_1 PF00515.28 OQS03339.1 - 2e-05 24.2 14.9 0.00017 21.3 0.0 4.8 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_11 PF13414.6 OQS03339.1 - 7.4e-05 22.3 3.2 0.021 14.5 0.0 3.9 3 0 0 3 3 3 1 TPR repeat TPR_MalT PF17874.1 OQS03339.1 - 0.00019 20.9 4.7 0.0016 17.9 1.6 2.2 2 0 0 2 2 2 1 MalT-like TPR region TPR_8 PF13181.6 OQS03339.1 - 0.0034 17.5 15.1 0.0043 17.2 0.0 5.7 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_7 PF13176.6 OQS03339.1 - 0.013 15.5 3.7 44 4.4 0.0 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat Methyltransf_28 PF02636.17 OQS03339.1 - 0.026 14.2 0.0 0.2 11.3 0.0 2.1 1 1 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase TPR_19 PF14559.6 OQS03339.1 - 0.033 14.7 5.3 0.056 14.0 0.0 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.6 OQS03339.1 - 0.52 11.1 11.0 17 6.3 0.3 5.7 5 0 0 5 5 5 0 Tetratricopeptide repeat DUF5525 PF17663.1 OQS03339.1 - 6.7 4.6 25.1 9.5 4.1 25.1 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5525) RNase_T PF00929.24 OQS03340.1 - 1.2e-07 32.4 0.0 1.6e-07 32.0 0.0 1.2 1 0 0 1 1 1 1 Exonuclease BT1 PF03092.16 OQS03342.1 - 5.9e-21 74.3 20.1 7.6e-10 37.6 0.4 4.2 4 0 0 4 4 4 4 BT1 family RNase_T PF00929.24 OQS03343.1 - 1e-24 87.9 0.0 1.2e-24 87.7 0.0 1.1 1 0 0 1 1 1 1 Exonuclease Trypsin_2 PF13365.6 OQS03344.1 - 7.1e-28 98.4 5.0 1.2e-14 55.5 1.3 2.6 2 0 0 2 2 2 2 Trypsin-like peptidase domain Ricin_B_lectin PF00652.22 OQS03344.1 - 1.5e-17 64.0 7.0 9.6e-11 42.0 0.1 3.2 3 0 0 3 3 3 2 Ricin-type beta-trefoil lectin domain CDtoxinA PF03498.14 OQS03344.1 - 0.00017 21.2 1.1 0.35 10.4 0.1 3.1 3 0 0 3 3 3 2 Cytolethal distending toxin A/C domain Peptidase_S46 PF10459.9 OQS03344.1 - 0.0022 16.7 9.9 0.11 11.2 0.1 4.0 4 0 0 4 4 4 2 Peptidase S46 zf-ZPR1 PF03367.13 OQS03344.1 - 0.029 14.2 0.4 2.1 8.2 0.1 2.7 2 0 0 2 2 2 0 ZPR1 zinc-finger domain IPK PF03770.16 OQS03346.1 - 3.6e-52 177.1 0.0 5e-52 176.6 0.0 1.2 1 0 0 1 1 1 1 Inositol polyphosphate kinase Coatomer_E PF04733.14 OQS03347.1 - 1.6e-06 27.8 0.1 0.03 13.8 0.0 3.0 2 1 0 2 2 2 2 Coatomer epsilon subunit TPR_14 PF13428.6 OQS03347.1 - 2e-06 28.1 14.5 0.76 10.8 0.1 7.4 5 2 3 8 8 8 3 Tetratricopeptide repeat TPR_16 PF13432.6 OQS03347.1 - 1.7e-05 25.4 14.5 0.00049 20.7 0.0 4.7 5 1 0 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.6 OQS03347.1 - 8.4e-05 22.8 20.9 0.043 14.1 0.0 6.7 3 3 2 7 7 7 2 Tetratricopeptide repeat TPR_2 PF07719.17 OQS03347.1 - 0.00017 21.5 17.7 4 7.8 0.1 8.7 8 1 1 9 9 9 1 Tetratricopeptide repeat TPR_11 PF13414.6 OQS03347.1 - 0.00024 20.7 0.5 0.00024 20.7 0.5 3.9 4 0 0 4 4 4 1 TPR repeat TPR_8 PF13181.6 OQS03347.1 - 0.0043 17.2 0.7 3.4 8.1 0.0 4.9 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_17 PF13431.6 OQS03347.1 - 0.0046 17.3 3.2 2.4 8.7 0.0 5.1 5 0 0 5 5 5 1 Tetratricopeptide repeat ANAPC3 PF12895.7 OQS03347.1 - 0.5 10.6 11.9 11 6.3 0.1 4.4 3 1 1 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.6 OQS03347.1 - 0.62 10.6 24.4 22 5.7 0.4 7.3 3 1 4 8 8 8 0 Tetratricopeptide repeat Biotin_lipoyl PF00364.22 OQS03349.1 - 2.2e-14 53.0 6.4 3.4e-14 52.4 6.4 1.3 1 0 0 1 1 1 1 Biotin-requiring enzyme S36_mt PF10937.8 OQS03349.1 - 1.4e-05 26.6 0.2 0.0056 18.3 0.0 2.5 1 1 1 2 2 2 2 Ribosomal protein S36, mitochondrial GCV_H PF01597.19 OQS03349.1 - 0.0089 15.9 0.9 0.015 15.1 0.9 1.4 1 0 0 1 1 1 1 Glycine cleavage H-protein Biotin_lipoyl_2 PF13533.6 OQS03349.1 - 0.25 11.2 4.7 2.9 7.8 0.2 2.4 1 1 1 2 2 2 0 Biotin-lipoyl like Med3 PF11593.8 OQS03349.1 - 0.43 9.7 2.3 0.57 9.3 2.3 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal PX PF00787.24 OQS03350.1 - 5.1e-09 36.1 0.0 6.4e-09 35.8 0.0 1.1 1 0 0 1 1 1 1 PX domain Glyoxalase PF00903.25 OQS03352.1 - 5.2e-06 26.7 0.0 9.2e-06 25.9 0.0 1.4 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 OQS03352.1 - 3.8e-05 24.4 0.0 4.7e-05 24.1 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_2 PF12681.7 OQS03352.1 - 0.00023 21.1 0.0 0.00036 20.4 0.0 1.3 1 1 0 1 1 1 1 Glyoxalase-like domain Autoind_bind PF03472.15 OQS03352.1 - 0.041 13.4 0.0 0.054 13.0 0.0 1.2 1 0 0 1 1 1 0 Autoinducer binding domain TruB_C PF09142.11 OQS03352.1 - 0.095 12.5 0.0 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 tRNA Pseudouridine synthase II, C terminal CppA_N PF14506.6 OQS03352.1 - 0.16 12.0 0.0 0.22 11.6 0.0 1.2 1 0 0 1 1 1 0 CppA N-terminal PIH1 PF08190.12 OQS03353.1 - 8e-29 100.2 0.2 1.9e-28 99.0 0.1 1.7 2 0 0 2 2 2 1 PIH1 N-terminal domain PIH1_CS PF18201.1 OQS03353.1 - 0.0019 18.5 1.3 0.0051 17.2 0.1 2.3 3 0 0 3 3 3 1 PIH1 CS-like domain Pox_I6 PF04595.13 OQS03354.1 - 0.018 14.0 0.1 0.036 13.0 0.1 1.4 1 0 0 1 1 1 0 Poxvirus I6-like family Rootletin PF15035.6 OQS03354.1 - 0.035 14.1 0.8 0.035 14.1 0.8 1.8 2 0 0 2 2 2 0 Ciliary rootlet component, centrosome cohesion zf-C4H2 PF10146.9 OQS03354.1 - 6.3 7.0 7.6 1.4 9.2 3.3 2.0 2 0 0 2 2 2 0 Zinc finger-containing protein DUF3958 PF13125.6 OQS03354.1 - 7.3 6.9 9.2 0.47 10.7 3.4 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3958) AAA_23 PF13476.6 OQS03355.1 - 1.5e-28 100.7 18.5 1.5e-28 100.7 18.5 8.7 3 2 1 4 4 4 1 AAA domain AAA_21 PF13304.6 OQS03355.1 - 5.4e-09 36.3 0.0 0.0017 18.3 0.0 2.9 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 OQS03355.1 - 3.7e-08 33.5 0.0 3.7e-08 33.5 0.0 5.1 2 2 1 3 3 3 2 AAA ATPase domain SbcCD_C PF13558.6 OQS03355.1 - 0.0014 18.8 0.0 0.0068 16.6 0.0 2.3 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit Rad50_zn_hook PF04423.14 OQS03355.1 - 0.0018 18.1 0.2 0.0018 18.1 0.2 5.3 6 0 0 6 6 6 1 Rad50 zinc hook motif ABC_tran PF00005.27 OQS03355.1 - 0.021 15.4 0.0 0.021 15.4 0.0 6.8 4 2 0 4 4 4 0 ABC transporter AAA_29 PF13555.6 OQS03355.1 - 0.035 13.8 0.0 0.082 12.7 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain SMC_N PF02463.19 OQS03355.1 - 0.07 12.6 51.1 2.1 7.7 51.1 3.6 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain AAA_28 PF13521.6 OQS03355.1 - 0.31 11.3 0.0 0.31 11.3 0.0 4.8 5 1 0 5 5 5 0 AAA domain AAA_16 PF13191.6 OQS03355.1 - 0.68 10.3 0.0 0.68 10.3 0.0 5.6 3 2 0 3 3 3 0 AAA ATPase domain DUF4196 PF13846.6 OQS03356.1 - 0.0094 16.1 0.7 0.038 14.2 0.7 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4196) RasGAP_C PF03836.15 OQS03356.1 - 0.26 11.4 1.6 0.88 9.7 1.0 2.0 2 0 0 2 2 2 0 RasGAP C-terminus AAA PF00004.29 OQS03357.1 - 2.1e-42 144.7 0.0 3.8e-42 143.8 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) MIT PF04212.18 OQS03357.1 - 2.7e-22 78.6 0.4 7.4e-22 77.2 0.4 1.8 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain Vps4_C PF09336.10 OQS03357.1 - 1.2e-10 41.2 0.0 4.1e-10 39.5 0.0 1.8 1 0 0 1 1 1 1 Vps4 C terminal oligomerisation domain Exo_endo_phos PF03372.23 OQS03357.1 - 3.7e-10 39.7 0.0 7.6e-10 38.7 0.0 1.6 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family RuvB_N PF05496.12 OQS03357.1 - 1.4e-05 24.9 0.0 4.4e-05 23.3 0.0 1.7 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 OQS03357.1 - 4.9e-05 23.3 0.0 0.0002 21.4 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 OQS03357.1 - 0.00011 22.6 0.0 0.0023 18.3 0.0 2.4 1 1 1 2 2 2 1 AAA ATPase domain IstB_IS21 PF01695.17 OQS03357.1 - 0.00015 21.6 0.0 0.00037 20.3 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_lid_3 PF17862.1 OQS03357.1 - 0.00029 20.6 0.9 0.0008 19.2 0.0 2.2 2 0 0 2 2 2 1 AAA+ lid domain AAA_22 PF13401.6 OQS03357.1 - 0.00046 20.5 0.1 0.013 15.8 0.1 2.4 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.6 OQS03357.1 - 0.00053 20.0 0.0 0.0014 18.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain DUF815 PF05673.13 OQS03357.1 - 0.00078 18.7 0.0 0.0016 17.6 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_2 PF07724.14 OQS03357.1 - 0.0013 18.9 0.0 0.0025 18.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_24 PF13479.6 OQS03357.1 - 0.0017 18.2 0.1 0.0089 15.8 0.0 2.0 2 0 0 2 2 2 1 AAA domain TIP49 PF06068.13 OQS03357.1 - 0.0029 16.8 0.0 0.0051 16.1 0.0 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_33 PF13671.6 OQS03357.1 - 0.0048 17.1 0.0 0.01 16.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 OQS03357.1 - 0.0051 17.3 0.0 0.013 16.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 OQS03357.1 - 0.0055 17.1 0.0 0.016 15.6 0.0 1.8 1 0 0 1 1 1 1 RNA helicase Parvo_NS1 PF01057.17 OQS03357.1 - 0.011 14.9 0.1 0.33 10.0 0.0 2.5 3 0 0 3 3 3 0 Parvovirus non-structural protein NS1 AAA_17 PF13207.6 OQS03357.1 - 0.041 14.3 0.1 0.096 13.1 0.0 1.7 2 0 0 2 2 1 0 AAA domain ATPase PF06745.13 OQS03357.1 - 0.051 12.9 0.1 5.8 6.2 0.0 2.3 1 1 1 2 2 2 0 KaiC AAA_25 PF13481.6 OQS03357.1 - 0.054 13.1 0.1 1.5 8.4 0.1 2.5 1 1 1 2 2 2 0 AAA domain Mg_chelatase PF01078.21 OQS03357.1 - 0.081 12.3 0.0 0.2 11.0 0.0 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_7 PF12775.7 OQS03357.1 - 0.093 12.2 0.0 0.29 10.6 0.0 1.8 2 0 0 2 2 2 0 P-loop containing dynein motor region NDK PF00334.19 OQS03358.1 - 2.1e-51 173.5 0.0 6.6e-51 171.9 0.0 1.8 2 0 0 2 2 2 1 Nucleoside diphosphate kinase NPL4 PF05021.15 OQS03358.1 - 5.8e-22 78.4 0.0 2e-19 70.1 0.0 3.1 1 1 0 2 2 2 2 NPL4 family UN_NPL4 PF11543.8 OQS03358.1 - 1.7e-06 28.4 0.0 3.7e-06 27.3 0.0 1.6 1 0 0 1 1 1 1 Nuclear pore localisation protein NPL4 ubiquitin PF00240.23 OQS03358.1 - 0.0014 18.3 0.0 0.085 12.6 0.0 3.0 3 0 0 3 3 3 1 Ubiquitin family DUF1707 PF08044.11 OQS03358.1 - 0.063 13.3 0.0 6.8 6.9 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1707) TRAPP PF04051.16 OQS03360.1 - 2.2e-37 128.0 0.0 3.4e-37 127.4 0.0 1.3 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component ING PF12998.7 OQS03360.1 - 9.3e-19 67.9 3.9 4e-09 37.0 0.3 2.6 2 0 0 2 2 2 2 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.29 OQS03360.1 - 0.014 15.2 2.7 0.027 14.4 2.7 1.4 1 0 0 1 1 1 0 PHD-finger zf-HC5HC2H PF13771.6 OQS03360.1 - 0.043 14.1 0.2 0.1 12.9 0.2 1.5 1 0 0 1 1 1 0 PHD-like zinc-binding domain NdhM PF10664.9 OQS03360.1 - 0.15 12.4 0.2 0.36 11.1 0.2 1.6 1 0 0 1 1 1 0 Cyanobacterial and plastid NDH-1 subunit M DNA_primase_S PF01896.19 OQS03361.1 - 8.2e-58 195.3 0.1 1.1e-57 194.9 0.1 1.2 1 0 0 1 1 1 1 DNA primase small subunit Ribosomal_L11_N PF03946.14 OQS03362.1 - 6.1e-21 74.0 0.3 1e-20 73.3 0.3 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.19 OQS03362.1 - 1.5e-16 60.6 0.1 2.5e-16 59.9 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain JmjC PF02373.22 OQS03363.1 - 6.6e-20 71.6 0.0 1.8e-19 70.3 0.0 1.8 1 0 0 1 1 1 1 JmjC domain, hydroxylase Cupin_8 PF13621.6 OQS03363.1 - 5.3e-17 62.4 0.1 1.2e-16 61.2 0.1 1.6 1 0 0 1 1 1 1 Cupin-like domain Turandot PF07240.11 OQS03363.1 - 0.061 13.3 0.0 0.33 11.0 0.0 2.2 2 0 0 2 2 2 0 Stress-inducible humoral factor Turandot Cupin_2 PF07883.11 OQS03363.1 - 0.071 12.8 0.1 0.14 11.9 0.1 1.4 1 0 0 1 1 1 0 Cupin domain BCNT PF07572.12 OQS03364.1 - 5.8e-27 93.6 2.5 5.8e-27 93.6 2.5 2.6 2 0 0 2 2 2 1 Bucentaur or craniofacial development Prefoldin PF02996.17 OQS03365.1 - 2.7e-17 62.8 0.4 2.7e-17 62.8 0.4 2.2 2 0 0 2 2 2 1 Prefoldin subunit TPR_2 PF07719.17 OQS03365.1 - 1.3e-15 56.2 7.1 3.2e-06 26.8 0.3 3.8 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.28 OQS03365.1 - 2.6e-14 52.3 6.3 9.8e-06 25.2 0.1 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.6 OQS03365.1 - 2.9e-09 36.4 4.6 3.6e-05 23.6 0.1 4.3 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 OQS03365.1 - 1.6e-08 34.1 4.3 0.0074 15.9 0.1 3.6 1 1 2 3 3 3 3 TPR repeat TPR_16 PF13432.6 OQS03365.1 - 1.1e-06 29.1 8.7 0.00028 21.4 1.6 2.8 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.6 OQS03365.1 - 1.7e-06 28.1 0.8 3e-05 24.1 0.7 2.5 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 OQS03365.1 - 2.7e-05 24.4 6.6 0.00019 21.6 2.7 3.0 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 OQS03365.1 - 4e-05 24.1 4.4 0.66 11.0 0.2 3.9 1 1 2 3 3 3 2 Tetratricopeptide repeat DUF3856 PF12968.7 OQS03365.1 - 0.0013 18.8 2.2 0.033 14.2 2.0 3.1 1 1 1 2 2 2 1 Domain of Unknown Function (DUF3856) TPR_7 PF13176.6 OQS03365.1 - 0.0013 18.6 1.2 0.44 10.7 0.0 4.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.6 OQS03365.1 - 0.0016 18.7 0.4 0.066 13.6 0.0 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat NPV_P10 PF05531.12 OQS03365.1 - 0.027 14.9 3.3 0.5 10.9 0.3 2.8 3 0 0 3 3 2 0 Nucleopolyhedrovirus P10 protein Prefoldin_3 PF13758.6 OQS03365.1 - 0.084 12.9 0.1 0.084 12.9 0.1 3.2 2 2 1 3 3 3 0 Prefoldin subunit GP41 PF00517.17 OQS03365.1 - 0.26 11.2 3.6 3.9 7.3 0.3 2.4 2 0 0 2 2 2 0 Retroviral envelope protein TPR_6 PF13174.6 OQS03365.1 - 0.29 11.9 6.4 3.9 8.3 0.4 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat SHNi-TPR PF10516.9 OQS03365.1 - 0.42 10.1 2.7 2.8 7.5 0.0 3.0 3 0 0 3 3 3 0 SHNi-TPR TPR_19 PF14559.6 OQS03365.1 - 0.92 10.1 6.5 1.3 9.6 0.5 3.1 2 1 0 3 3 2 0 Tetratricopeptide repeat Atg14 PF10186.9 OQS03365.1 - 2.1 7.4 8.6 0.18 10.8 3.0 2.0 2 1 1 3 3 3 0 Vacuolar sorting 38 and autophagy-related subunit 14 Lyase_aromatic PF00221.19 OQS03366.1 - 4.8e-191 635.4 1.7 7.3e-191 634.8 1.7 1.3 1 1 0 1 1 1 1 Aromatic amino acid lyase Pkinase PF00069.25 OQS03367.1 - 1.4e-70 237.7 0.1 3e-70 236.6 0.1 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQS03367.1 - 6.9e-29 100.9 0.7 5.8e-21 74.9 0.1 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Haspin_kinase PF12330.8 OQS03367.1 - 6e-07 28.7 0.1 6e-07 28.7 0.1 2.3 2 1 0 2 2 2 1 Haspin like kinase domain Kinase-like PF14531.6 OQS03367.1 - 0.0011 18.4 0.1 0.068 12.5 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.14 OQS03367.1 - 0.0055 16.1 0.6 0.028 13.8 0.4 2.0 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family PEP_mutase PF13714.6 OQS03368.1 - 6.4e-54 182.9 0.0 7.3e-54 182.7 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase ICL PF00463.21 OQS03368.1 - 4.1e-14 52.0 0.2 5.5e-14 51.6 0.2 1.1 1 0 0 1 1 1 1 Isocitrate lyase family Pantoate_transf PF02548.15 OQS03368.1 - 0.00086 18.8 0.0 0.0025 17.2 0.0 2.0 1 1 0 1 1 1 1 Ketopantoate hydroxymethyltransferase RFC1 PF08519.12 OQS03369.1 - 5.5e-38 130.6 0.1 1.8e-37 128.9 0.1 2.0 1 0 0 1 1 1 1 Replication factor RFC1 C terminal domain Ank_2 PF12796.7 OQS03369.1 - 1.1e-24 86.8 17.2 4.3e-06 27.2 0.1 7.2 6 1 0 6 6 6 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQS03369.1 - 2e-19 69.7 17.4 0.00018 22.0 0.0 8.3 6 1 3 9 9 9 7 Ankyrin repeats (many copies) MORN PF02493.20 OQS03369.1 - 2.4e-18 64.8 16.1 7.9e-08 31.8 0.6 6.0 6 0 0 6 6 6 3 MORN repeat Ank_5 PF13857.6 OQS03369.1 - 2.8e-18 65.7 15.4 0.028 14.8 0.1 9.2 6 3 4 10 10 9 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQS03369.1 - 1.9e-13 49.3 10.5 5.6 7.9 0.0 12.0 12 0 0 12 12 12 1 Ankyrin repeat AAA PF00004.29 OQS03369.1 - 5.4e-13 49.5 0.1 1.3e-12 48.3 0.1 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) BRCT PF00533.26 OQS03369.1 - 2.7e-12 46.9 0.0 2.1e-11 44.0 0.0 2.6 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain AAA_5 PF07728.14 OQS03369.1 - 6.8e-05 22.9 0.0 0.00021 21.3 0.0 1.9 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 OQS03369.1 - 9.5e-05 22.2 0.0 0.00026 20.8 0.0 1.7 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_30 PF13604.6 OQS03369.1 - 0.00011 22.0 0.1 0.00023 20.9 0.1 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 OQS03369.1 - 0.00024 21.5 0.0 0.00059 20.3 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 OQS03369.1 - 0.00042 20.6 0.0 0.0013 19.0 0.0 1.8 1 0 0 1 1 1 1 AAA domain DNA_pol3_delta PF06144.13 OQS03369.1 - 0.00094 19.0 0.0 0.0031 17.3 0.0 1.8 1 0 0 1 1 1 1 DNA polymerase III, delta subunit NACHT PF05729.12 OQS03369.1 - 0.0019 18.1 0.1 0.0045 16.9 0.1 1.6 1 0 0 1 1 1 1 NACHT domain NTPase_1 PF03266.15 OQS03369.1 - 0.0029 17.5 0.1 0.17 11.8 0.0 2.5 1 1 1 2 2 2 1 NTPase AAA_14 PF13173.6 OQS03369.1 - 0.003 17.6 0.0 0.0093 16.0 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 OQS03369.1 - 0.0053 17.3 1.3 0.035 14.7 0.0 3.1 3 0 0 3 3 3 1 AAA domain RNA_helicase PF00910.22 OQS03369.1 - 0.017 15.5 0.0 0.19 12.2 0.0 2.7 1 1 0 1 1 1 0 RNA helicase AAA_33 PF13671.6 OQS03369.1 - 0.017 15.3 0.0 0.09 12.9 0.0 2.2 2 0 0 2 2 1 0 AAA domain RsgA_GTPase PF03193.16 OQS03369.1 - 0.018 14.9 0.0 0.052 13.5 0.0 1.7 1 0 0 1 1 1 0 RsgA GTPase IstB_IS21 PF01695.17 OQS03369.1 - 0.027 14.2 0.0 0.087 12.6 0.0 1.8 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_2 PF07724.14 OQS03369.1 - 0.028 14.5 0.0 0.095 12.8 0.0 1.9 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) Sigma54_activ_2 PF14532.6 OQS03369.1 - 0.049 13.7 0.1 0.35 11.0 0.0 2.2 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_19 PF13245.6 OQS03369.1 - 0.076 13.3 0.3 1.2 9.5 0.3 2.4 1 1 0 1 1 1 0 AAA domain AAA_7 PF12775.7 OQS03369.1 - 0.084 12.4 0.0 0.18 11.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region Ig_3 PF13927.6 OQS03370.1 - 3.3e-06 27.6 0.0 1e-05 26.1 0.0 1.9 1 0 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.6 OQS03370.1 - 7.5e-06 26.2 0.4 2.1e-05 24.7 0.1 1.9 2 0 0 2 2 2 1 Immunoglobulin domain I-set PF07679.16 OQS03370.1 - 8.5e-05 22.5 0.1 0.00051 20.0 0.1 2.3 1 1 0 1 1 1 1 Immunoglobulin I-set domain ZU5 PF00791.20 OQS03370.1 - 0.014 15.7 0.0 0.072 13.4 0.0 2.2 1 1 0 1 1 1 0 ZU5 domain V-set PF07686.17 OQS03370.1 - 0.076 13.2 0.5 0.3 11.3 0.1 2.3 2 1 0 2 2 2 0 Immunoglobulin V-set domain ig PF00047.25 OQS03370.1 - 0.13 12.4 1.2 0.46 10.7 0.3 2.3 2 0 0 2 2 2 0 Immunoglobulin domain Receptor_2B4 PF11465.8 OQS03370.1 - 0.15 12.3 0.0 0.41 10.9 0.0 1.7 1 0 0 1 1 1 0 Natural killer cell receptor 2B4 Ig_5 PF16681.5 OQS03370.1 - 0.17 12.3 0.3 0.77 10.2 0.0 2.2 2 0 0 2 2 2 0 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain FlaC_arch PF05377.11 OQS03371.1 - 0.0013 19.1 5.3 0.033 14.6 0.0 4.0 4 0 0 4 4 4 1 Flagella accessory protein C (FlaC) bZIP_1 PF00170.21 OQS03371.1 - 0.052 13.6 0.2 0.052 13.6 0.2 4.7 2 2 2 4 4 4 0 bZIP transcription factor ZapB PF06005.12 OQS03371.1 - 0.34 11.4 37.5 1.1 9.7 4.9 5.1 2 2 1 3 3 3 0 Cell division protein ZapB DUF1664 PF07889.12 OQS03371.1 - 0.36 10.9 18.4 0.11 12.6 1.8 3.7 1 1 1 3 3 3 0 Protein of unknown function (DUF1664) DUF2949 PF11165.8 OQS03371.1 - 0.65 10.4 4.3 12 6.3 0.7 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2949) DUF4988 PF16378.5 OQS03371.1 - 0.71 9.5 6.8 1.4 8.5 0.6 3.0 2 1 0 3 3 3 0 Domain of unknown function UPF0242 PF06785.11 OQS03371.1 - 2.2 8.3 36.0 0.68 10.0 19.4 2.6 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Seryl_tRNA_N PF02403.22 OQS03371.1 - 2.4 8.4 29.5 1.8 8.8 4.6 3.4 2 1 1 3 3 3 0 Seryl-tRNA synthetase N-terminal domain KASH_CCD PF14662.6 OQS03371.1 - 2.6 7.8 35.8 11 5.7 19.7 3.3 1 1 0 2 2 2 0 Coiled-coil region of CCDC155 or KASH Cauli_AT PF03233.13 OQS03371.1 - 3.3 7.6 14.8 8.8 6.2 3.6 3.0 2 1 0 2 2 2 0 Aphid transmission protein Syntaxin-6_N PF09177.11 OQS03371.1 - 4.6 7.8 16.3 10 6.8 1.9 3.2 1 1 0 2 2 2 0 Syntaxin 6, N-terminal Cnn_1N PF07989.11 OQS03371.1 - 5.4 7.2 28.6 10 6.4 6.3 4.7 2 2 2 4 4 4 0 Centrosomin N-terminal motif 1 DASH_Hsk3 PF08227.11 OQS03371.1 - 7.3 7.0 10.1 18 5.8 0.3 3.4 3 0 0 3 3 2 0 DASH complex subunit Hsk3 like Hist_deacetyl PF00850.19 OQS03372.1 - 1.4e-148 494.4 4.0 3.7e-74 250.0 0.1 2.3 2 0 0 2 2 2 2 Histone deacetylase domain Peripla_BP_7 PF18610.1 OQS03372.1 - 0.006 16.7 0.0 6.6 6.9 0.0 2.7 2 0 0 2 2 2 2 Periplasmic binding protein domain DUF1256 PF06866.11 OQS03372.1 - 0.15 11.5 0.0 14 5.0 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1256) SAC3_GANP PF03399.16 OQS03373.1 - 0.0068 15.8 1.8 0.0068 15.8 1.8 1.8 2 1 0 2 2 2 1 SAC3/GANP family GBP_repeat PF02526.14 OQS03373.1 - 0.12 12.1 0.1 0.3 10.8 0.1 1.7 1 0 0 1 1 1 0 Glycophorin-binding protein L27 PF02828.16 OQS03373.1 - 0.82 9.5 5.8 0.11 12.3 1.2 1.9 2 0 0 2 2 2 0 L27 domain Cdh1_DBD_1 PF18196.1 OQS03373.1 - 5.9 7.2 10.7 0.77 10.1 4.9 2.4 2 1 0 2 2 2 0 Chromodomain helicase DNA-binding domain 1 DUF2115 PF09888.9 OQS03373.1 - 6.8 7.2 6.9 8.2 6.9 1.8 2.6 2 1 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2115) Acyl_transf_3 PF01757.22 OQS03374.1 - 4.2e-44 151.0 83.0 1.8e-24 86.4 32.9 3.6 2 2 2 4 4 4 2 Acyltransferase family OST3_OST6 PF04756.13 OQS03374.1 - 0.056 12.8 6.5 0.51 9.6 1.6 2.9 2 0 0 2 2 2 0 OST3 / OST6 family, transporter family Pox_A9 PF04835.12 OQS03374.1 - 0.061 13.5 8.1 1.4 9.1 0.4 4.1 3 0 0 3 3 3 0 A9 protein conserved region PHO4 PF01384.20 OQS03374.1 - 1.4 7.9 10.9 1.9 7.4 0.0 3.7 3 1 0 3 3 3 0 Phosphate transporter family DUF4149 PF13664.6 OQS03374.1 - 8.7 6.7 16.0 13 6.1 0.5 5.1 4 0 0 4 4 4 0 Domain of unknown function (DUF4149) LRR_6 PF13516.6 OQS03376.1 - 7.6e-37 122.2 56.5 0.0015 18.4 0.2 18.8 19 0 0 19 19 19 15 Leucine Rich repeat LRR_4 PF12799.7 OQS03376.1 - 3.5e-33 113.1 41.7 5.5e-06 26.6 0.2 13.0 5 4 10 15 15 15 14 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 OQS03376.1 - 1.1e-19 69.9 28.9 0.00019 21.1 0.2 9.1 6 2 5 11 11 11 9 Leucine rich repeat LRR_1 PF00560.33 OQS03376.1 - 1.1e-09 37.4 47.0 2.3 9.1 0.8 16.0 17 3 1 18 18 18 4 Leucine Rich Repeat RNA_pol_A_CTD PF03118.15 OQS03376.1 - 0.0017 18.0 6.0 4.7 7.0 0.2 5.5 6 0 0 6 6 6 1 Bacterial RNA polymerase, alpha chain C terminal domain DUF3744 PF12558.8 OQS03376.1 - 1.7 9.5 6.1 96 3.9 0.1 5.2 5 2 1 6 6 6 0 ATP-binding cassette cobalt transporter DUF3737 PF12541.8 OQS03376.1 - 3.3 6.8 7.9 0.85 8.8 1.9 3.0 3 2 1 4 4 4 0 Protein of unknown function (DUF3737) HECT PF00632.25 OQS03377.1 - 2.4e-75 253.9 0.1 4e-75 253.2 0.1 1.4 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Ricin_B_lectin PF00652.22 OQS03377.1 - 1.8e-63 212.4 60.6 4.8e-14 52.7 8.5 5.9 5 1 1 6 6 6 5 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.6 OQS03377.1 - 1.4e-23 83.4 61.6 6.4e-07 30.0 3.2 8.4 6 2 2 8 8 8 6 Ricin-type beta-trefoil lectin domain-like zf-RanBP PF00641.18 OQS03377.1 - 0.00071 18.8 4.3 0.0048 16.2 4.3 2.6 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others WWE PF02825.20 OQS03377.1 - 0.012 16.2 1.4 0.74 10.4 0.1 3.7 2 0 0 2 2 2 0 WWE domain NICE-1 PF15845.5 OQS03377.1 - 0.054 14.3 0.5 0.22 12.3 0.5 2.0 1 0 0 1 1 1 0 Cysteine-rich C-terminal 1 family zf-Sec23_Sec24 PF04810.15 OQS03377.1 - 0.057 13.5 0.2 0.057 13.5 0.2 3.0 3 0 0 3 3 3 0 Sec23/Sec24 zinc finger ET PF01684.16 OQS03377.1 - 1.2 9.5 20.8 0.35 11.2 0.2 6.1 5 1 1 6 6 6 0 ET module Pkinase PF00069.25 OQS03378.1 - 1.9e-50 171.7 0.1 2.8e-50 171.1 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQS03378.1 - 3.9e-47 160.7 0.0 5.4e-47 160.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 OQS03378.1 - 0.00051 19.1 0.2 0.04 12.9 0.2 2.2 1 1 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 OQS03378.1 - 0.00084 19.3 0.0 0.0014 18.6 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 OQS03378.1 - 0.0022 16.9 0.0 0.004 16.0 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 OQS03378.1 - 0.038 13.3 0.0 0.066 12.5 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 OQS03378.1 - 0.12 12.0 0.0 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 RIO1 family FTA2 PF13095.6 OQS03378.1 - 0.27 10.8 0.6 1.2 8.7 0.1 2.0 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 zf-TFIIB PF13453.6 OQS03380.1 - 3.1 7.2 5.2 50 3.3 4.2 2.6 2 1 0 2 2 2 0 Transcription factor zinc-finger zf-TFIIB PF13453.6 OQS03381.1 - 1.5 8.2 4.4 25 4.3 3.4 2.6 2 1 0 2 2 2 0 Transcription factor zinc-finger Cyt-b5 PF00173.28 OQS03383.1 - 8.3e-11 41.9 0.0 1.7e-10 40.9 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DUF1126 PF06565.12 OQS03384.1 - 6.6e-89 292.7 3.9 9.7e-29 99.3 0.2 3.2 3 0 0 3 3 3 3 DUF1126 PH-like domain CYYR1 PF10873.8 OQS03384.1 - 0.0058 17.1 1.5 0.0097 16.4 1.5 1.3 1 0 0 1 1 1 1 Cysteine and tyrosine-rich protein 1 Phage_holin_4_1 PF05105.12 OQS03384.1 - 0.044 13.9 0.0 15 5.8 0.0 2.3 2 0 0 2 2 2 0 Bacteriophage holin family Ank_2 PF12796.7 OQS03385.1 - 5.1e-30 103.9 7.5 7.2e-06 26.5 0.1 7.7 5 1 2 7 7 7 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQS03385.1 - 4.3e-28 97.3 5.8 0.0004 20.9 0.0 10.2 9 3 0 9 9 9 7 Ankyrin repeats (many copies) Ank_5 PF13857.6 OQS03385.1 - 1e-19 70.3 6.4 0.00045 20.5 0.0 11.3 5 3 8 13 13 13 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQS03385.1 - 9.7e-12 44.0 5.6 10 7.1 0.0 12.0 14 0 0 14 14 14 2 Ankyrin repeat Ank PF00023.30 OQS03385.1 - 0.0033 17.8 4.3 53 4.5 0.0 6.7 5 2 0 5 5 5 0 Ankyrin repeat DUF4116 PF13475.6 OQS03385.1 - 0.16 11.7 0.7 2.9 7.7 0.0 3.2 2 1 1 3 3 3 0 Domain of unknown function (DUF4116) IPK PF03770.16 OQS03386.1 - 1e-47 162.6 0.1 2.1e-47 161.6 0.1 1.6 1 0 0 1 1 1 1 Inositol polyphosphate kinase GLTP PF08718.11 OQS03386.1 - 9e-14 52.0 0.1 2e-13 50.9 0.1 1.5 1 0 0 1 1 1 1 Glycolipid transfer protein (GLTP) LRR_4 PF12799.7 OQS03386.1 - 3.8e-12 46.2 20.2 2e-07 31.2 7.0 5.1 3 1 1 4 4 4 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 OQS03386.1 - 2.4e-10 40.0 18.3 8.3e-06 25.5 9.7 2.9 2 0 0 2 2 2 2 Leucine rich repeat LRR_9 PF14580.6 OQS03386.1 - 1.1e-06 28.3 1.2 6.6e-05 22.5 0.1 2.5 1 1 1 2 2 2 2 Leucine-rich repeat LRR_6 PF13516.6 OQS03386.1 - 0.0011 18.8 7.0 2.5 8.4 0.3 4.2 3 0 0 3 3 3 2 Leucine Rich repeat LRR_1 PF00560.33 OQS03386.1 - 0.22 12.2 13.6 18 6.4 1.9 5.1 4 0 0 4 4 4 0 Leucine Rich Repeat cNMP_binding PF00027.29 OQS03387.1 - 2.4e-08 34.0 0.0 0.0022 18.0 0.0 3.9 4 0 0 4 4 4 2 Cyclic nucleotide-binding domain TPR_2 PF07719.17 OQS03387.1 - 2.7e-06 27.0 0.4 2.6 8.4 0.0 4.9 4 0 0 4 4 4 2 Tetratricopeptide repeat Response_reg PF00072.24 OQS03387.1 - 0.0011 19.1 0.0 0.0029 17.7 0.0 1.7 1 0 0 1 1 1 1 Response regulator receiver domain TPR_1 PF00515.28 OQS03387.1 - 0.0019 17.9 0.0 12 6.0 0.0 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.6 OQS03387.1 - 0.053 13.8 0.0 56 4.3 0.0 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat SPO22 PF08631.10 OQS03387.1 - 0.29 10.6 2.4 14 5.1 0.3 2.4 2 0 0 2 2 2 0 Meiosis protein SPO22/ZIP4 like Ank_4 PF13637.6 OQS03388.1 - 1.8e-11 44.3 0.4 0.0047 17.5 0.1 4.6 3 1 1 4 4 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 OQS03388.1 - 3.8e-11 43.4 0.9 0.00051 20.6 0.0 3.6 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OQS03388.1 - 2.8e-07 30.7 0.8 0.55 10.6 0.0 5.3 2 2 3 5 5 5 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQS03388.1 - 0.00047 20.4 0.1 1.8 9.4 0.0 4.5 4 0 0 4 4 4 1 Ankyrin repeat Ank_5 PF13857.6 OQS03389.1 - 6.8e-09 35.8 0.3 1.1e-07 32.0 0.1 2.6 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 OQS03389.1 - 1.9e-08 34.7 1.6 2.2e-07 31.4 0.2 2.7 2 1 0 3 3 3 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQS03389.1 - 2.9e-08 34.1 2.3 7.5e-05 23.2 0.4 3.1 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 OQS03389.1 - 1.7e-06 28.2 1.9 8.1e-06 26.1 0.1 3.0 3 0 0 3 3 3 1 Ankyrin repeat Ank_3 PF13606.6 OQS03389.1 - 8.7e-06 25.7 0.8 0.0019 18.6 0.1 3.2 2 0 0 2 2 2 1 Ankyrin repeat Barwin PF00967.17 OQS03389.1 - 0.27 11.1 1.8 0.43 10.4 0.2 2.1 3 0 0 3 3 3 0 Barwin family DDE_Tnp_1_7 PF13843.6 OQS03390.1 - 1.9e-12 47.2 0.0 2.3e-12 46.9 0.0 1.1 1 0 0 1 1 1 1 Transposase IS4 cNMP_binding PF00027.29 OQS03391.1 - 5.9e-28 96.8 0.1 7.2e-14 51.6 0.0 2.6 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain RNase_T PF00929.24 OQS03391.1 - 0.099 13.2 4.5 0.13 12.8 0.7 2.6 2 0 0 2 2 2 0 Exonuclease SPAM PF02090.15 OQS03391.1 - 0.82 9.5 5.0 0.24 11.2 0.2 2.3 2 0 0 2 2 2 0 Salmonella surface presentation of antigen gene type M protein HA2 PF04408.23 OQS03392.1 - 1.6e-24 86.3 0.1 3.1e-24 85.3 0.1 1.5 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 OQS03392.1 - 5.6e-21 74.7 0.0 1.3e-20 73.5 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 OQS03392.1 - 6.4e-11 42.6 0.0 1.1e-10 41.9 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HTH_IclR PF09339.10 OQS03392.1 - 0.79 9.6 3.2 0.31 10.9 0.4 1.7 2 0 0 2 2 2 0 IclR helix-turn-helix domain CCDC23 PF15674.5 OQS03393.1 - 0.031 14.3 9.8 0.031 14.3 9.8 2.2 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 23 Ndc1_Nup PF09531.10 OQS03393.1 - 6.1 5.4 11.7 7.1 5.2 11.7 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup FYVE_2 PF02318.16 OQS03395.1 - 0.0002 21.6 37.6 0.00042 20.5 4.4 3.7 3 0 0 3 3 3 2 FYVE-type zinc finger Coilin_N PF15862.5 OQS03395.1 - 0.12 12.2 0.6 0.56 10.0 0.1 2.2 2 0 0 2 2 2 0 Coilin N-terminus DUF2024 PF09630.10 OQS03395.1 - 7 6.6 8.0 6 6.8 2.5 3.1 2 0 0 2 2 2 0 Domain of unknown function (DUF2024) MFS_1 PF07690.16 OQS03396.1 - 2.7e-08 33.1 44.0 8.7e-05 21.6 15.4 3.3 2 1 1 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.24 OQS03396.1 - 0.013 14.4 25.3 0.071 12.0 17.2 3.7 1 1 2 3 3 3 0 Sugar (and other) transporter MFS_1 PF07690.16 OQS03397.1 - 2.9e-14 52.8 24.1 4e-14 52.3 24.1 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Telomerase_RBD PF12009.8 OQS03397.1 - 0.047 13.8 0.6 0.082 13.0 0.6 1.4 1 0 0 1 1 1 0 Telomerase ribonucleoprotein complex - RNA binding domain AAA_26 PF13500.6 OQS03399.1 - 4.5e-19 69.1 0.0 7.5e-19 68.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain CbiA PF01656.23 OQS03399.1 - 0.0041 17.2 0.1 0.0095 16.0 0.1 1.9 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain DUF1611 PF07755.11 OQS03399.1 - 0.048 12.9 0.0 0.11 11.8 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1611_C) P-loop domain Helicase_C PF00271.31 OQS03400.1 - 3.8e-21 75.5 0.0 1.4e-20 73.7 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain SNF2_N PF00176.23 OQS03400.1 - 1.5e-11 43.6 0.0 2.5e-11 42.9 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Beta_helix PF13229.6 OQS03400.1 - 9.9e-11 41.7 7.9 2.4e-10 40.5 7.5 1.7 2 0 0 2 2 2 1 Right handed beta helix region NosD PF05048.13 OQS03400.1 - 3.9e-05 23.0 0.8 6.6e-05 22.3 0.8 1.3 1 0 0 1 1 1 1 Periplasmic copper-binding protein (NosD) WW PF00397.26 OQS03400.1 - 0.00073 19.6 0.0 0.0016 18.5 0.0 1.5 1 0 0 1 1 1 1 WW domain ERCC3_RAD25_C PF16203.5 OQS03400.1 - 0.01 15.1 0.1 0.01 15.1 0.1 1.9 2 0 0 2 2 2 0 ERCC3/RAD25/XPB C-terminal helicase F-box-like PF12937.7 OQS03400.1 - 0.023 14.6 0.8 0.056 13.3 0.8 1.6 1 0 0 1 1 1 0 F-box-like mRNA_triPase PF02940.15 OQS03401.1 - 8.2e-24 84.5 0.0 2.1e-23 83.2 0.0 1.6 1 1 0 1 1 1 1 mRNA capping enzyme, beta chain mRNA_cap_enzyme PF01331.19 OQS03401.1 - 2.3e-13 50.4 0.0 3.4e-13 49.9 0.0 1.3 1 0 0 1 1 1 1 mRNA capping enzyme, catalytic domain PPR_2 PF13041.6 OQS03404.1 - 9.7e-21 73.7 0.8 6.8e-06 26.2 0.1 6.3 5 3 2 7 7 7 3 PPR repeat family PPR PF01535.20 OQS03404.1 - 1.1e-15 56.6 5.5 0.0006 19.9 0.0 10.1 10 1 0 10 10 10 4 PPR repeat PPR_3 PF13812.6 OQS03404.1 - 2.4e-11 43.5 0.2 0.19 11.8 0.0 6.2 4 2 4 8 8 8 5 Pentatricopeptide repeat domain PPR_long PF17177.4 OQS03404.1 - 6.2e-11 42.1 5.3 7.7e-05 22.2 0.0 4.8 4 1 1 5 5 5 4 Pentacotripeptide-repeat region of PRORP BTAD PF03704.17 OQS03404.1 - 0.0089 16.5 4.2 1.8 9.0 0.0 5.1 4 1 0 5 5 5 1 Bacterial transcriptional activator domain YlqD PF11068.8 OQS03404.1 - 0.17 12.2 1.9 0.36 11.2 1.9 1.5 1 0 0 1 1 1 0 YlqD protein CCT PF06203.14 OQS03405.1 - 4.1e-06 26.7 2.8 6.6e-06 26.1 2.8 1.3 1 0 0 1 1 1 1 CCT motif COBRA PF04833.15 OQS03405.1 - 0.024 14.5 0.0 0.042 13.8 0.0 1.4 1 0 0 1 1 1 0 COBRA-like protein Hist_deacetyl PF00850.19 OQS03406.1 - 4.5e-58 197.1 0.0 5.5e-58 196.8 0.0 1.0 1 0 0 1 1 1 1 Histone deacetylase domain ATG_C PF09333.11 OQS03407.1 - 6e-29 100.2 1.9 1.8e-28 98.7 0.1 2.6 3 0 0 3 3 3 1 Autophagy-related protein C terminal domain Chorein_N PF12624.7 OQS03407.1 - 1.6e-21 76.6 0.6 1.3e-20 73.7 0.1 2.8 3 0 0 3 3 3 1 N-terminal region of Chorein or VPS13 ATG2_CAD PF13329.6 OQS03407.1 - 8.1e-07 28.9 0.1 3.9e-06 26.7 0.0 2.2 2 0 0 2 2 2 1 Autophagy-related protein 2 CAD motif VPS13_C PF16909.5 OQS03407.1 - 1.3e-06 28.3 0.0 3.1e-05 23.8 0.0 2.9 3 0 0 3 3 3 1 Vacuolar-sorting-associated 13 protein C-terminal T2SSM PF04612.12 OQS03407.1 - 0.005 16.9 0.2 0.081 13.0 0.0 2.6 2 0 0 2 2 2 1 Type II secretion system (T2SS), protein M Baculo_8kDa PF06096.11 OQS03407.1 - 0.13 12.4 0.0 0.37 10.9 0.0 1.7 1 0 0 1 1 1 0 Baculoviridae 8.2 KDa protein TcdB_N PF12918.7 OQS03407.1 - 0.89 9.9 2.9 26 5.2 0.1 3.2 3 0 0 3 3 3 0 TcdB toxin N-terminal helical domain MRNIP PF15749.5 OQS03408.1 - 0.077 13.7 0.3 0.089 13.5 0.3 1.2 1 0 0 1 1 1 0 MRN-interacting protein ANAPC4_WD40 PF12894.7 OQS03409.1 - 0.0001 22.5 0.0 1.3 9.4 0.0 3.7 4 1 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 OQS03409.1 - 0.01 16.7 5.3 2.2 9.3 0.0 4.7 4 1 1 5 5 5 0 WD domain, G-beta repeat IBN_N PF03810.19 OQS03410.1 - 1.3e-09 37.9 2.1 1.4e-09 37.8 0.3 2.0 2 0 0 2 2 2 1 Importin-beta N-terminal domain Med26 PF08711.11 OQS03411.1 - 0.00016 21.6 2.3 0.00025 21.0 0.6 2.3 2 0 0 2 2 2 1 TFIIS helical bundle-like domain Ank_2 PF12796.7 OQS03412.1 - 3.4e-53 178.2 4.4 1.7e-11 44.6 0.1 5.1 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQS03412.1 - 2.7e-44 149.0 9.0 6.5e-10 39.3 0.0 7.1 1 1 8 9 9 9 8 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQS03412.1 - 2.9e-40 131.7 0.3 3e-05 24.1 0.0 8.3 8 0 0 8 8 8 7 Ankyrin repeat Ank_5 PF13857.6 OQS03412.1 - 1.2e-36 124.3 11.6 1.4e-07 31.7 0.0 6.2 1 1 7 8 8 8 8 Ankyrin repeats (many copies) Ank PF00023.30 OQS03412.1 - 7e-31 105.3 13.2 0.00028 21.2 0.0 8.1 8 0 0 8 8 8 7 Ankyrin repeat EPSP_synthase PF00275.20 OQS03412.1 - 0.00034 19.4 0.1 1.7 7.3 0.0 3.8 2 2 2 4 4 4 2 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) PEGA PF08308.11 OQS03412.1 - 0.0012 18.7 0.3 9 6.3 0.0 4.4 5 0 0 5 5 5 1 PEGA domain DHQS PF01959.16 OQS03412.1 - 0.0012 17.8 0.2 11 4.8 0.1 4.1 2 2 2 4 4 4 2 3-dehydroquinate synthase II DUF3447 PF11929.8 OQS03412.1 - 0.0046 16.9 0.1 0.017 15.1 0.0 2.1 2 1 0 2 2 2 1 Domain of unknown function (DUF3447) ZapB PF06005.12 OQS03413.1 - 0.0083 16.5 4.6 0.0083 16.5 4.6 14.9 5 3 5 11 11 11 3 Cell division protein ZapB Fungal_TACC PF12709.7 OQS03413.1 - 0.017 15.5 1.9 0.017 15.5 1.9 14.0 8 6 9 17 17 17 0 Fungal Transforming acidic coiled-coil (TACC) proteins DprA_WH PF17782.1 OQS03413.1 - 0.019 15.1 0.0 0.063 13.4 0.0 1.9 1 0 0 1 1 1 0 DprA winged helix domain HALZ PF02183.18 OQS03413.1 - 0.03 14.5 0.2 0.03 14.5 0.2 8.5 8 1 1 9 9 9 0 Homeobox associated leucine zipper S-l_SbsC_C PF18316.1 OQS03414.1 - 0.031 14.8 0.1 0.08 13.4 0.1 1.8 1 1 0 1 1 1 0 S-layer protein SbsC C-terminal domain Peptidase_S10 PF00450.22 OQS03415.1 - 1.8e-122 409.7 0.2 2.2e-122 409.5 0.2 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase UL42 PF17638.2 OQS03415.1 - 0.047 13.7 0.1 0.093 12.7 0.1 1.4 1 0 0 1 1 1 0 HCMV UL42 SieB PF14163.6 OQS03415.1 - 0.15 11.6 0.1 0.26 10.8 0.1 1.3 1 0 0 1 1 1 0 Super-infection exclusion protein B Peptidase_S10 PF00450.22 OQS03416.1 - 1.4e-27 97.2 2.0 1.6e-27 97.0 2.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Say1_Mug180 PF10340.9 OQS03416.1 - 0.12 11.2 0.0 0.17 10.7 0.0 1.5 1 1 0 1 1 1 0 Steryl acetyl hydrolase SET PF00856.28 OQS03417.1 - 1.9e-19 70.6 2.4 3.7e-05 24.2 0.2 4.1 3 1 0 3 3 3 3 SET domain DUF871 PF05913.11 OQS03417.1 - 5.3e-05 22.6 4.5 0.18 10.9 0.6 3.3 3 0 0 3 3 3 2 Bacterial protein of unknown function (DUF871) TPR_2 PF07719.17 OQS03417.1 - 0.0075 16.3 3.3 0.22 11.7 0.4 3.3 2 0 0 2 2 2 1 Tetratricopeptide repeat SAF PF08666.12 OQS03417.1 - 0.072 13.7 0.6 1.1e+02 3.5 0.1 4.8 5 0 0 5 5 5 0 SAF domain DC_STAMP PF07782.13 OQS03417.1 - 0.11 12.3 0.0 9.3 6.0 0.0 2.5 2 0 0 2 2 2 0 DC-STAMP-like protein TPR_8 PF13181.6 OQS03417.1 - 0.11 12.7 8.3 0.34 11.2 0.5 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat His_Phos_2 PF00328.22 OQS03417.1 - 0.12 11.7 2.6 0.59 9.4 0.0 2.5 3 0 0 3 3 3 0 Histidine phosphatase superfamily (branch 2) TPR_10 PF13374.6 OQS03417.1 - 0.18 11.7 8.5 0.75 9.8 0.6 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat Thioredoxin_13 PF18401.1 OQS03417.1 - 0.19 11.7 1.2 11 5.9 0.2 3.2 3 0 0 3 3 3 0 Thioredoxin-like domain DUF1137 PF06587.11 OQS03417.1 - 0.46 10.5 8.9 2.1 8.4 0.2 4.5 5 0 0 5 5 5 0 Protein of unknown function (DUF1137) TPR_12 PF13424.6 OQS03417.1 - 0.69 10.2 11.5 2.4 8.5 0.5 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat zf-H2C2_2 PF13465.6 OQS03417.1 - 2.5 8.7 7.2 1.6 9.3 0.6 3.8 3 0 0 3 3 3 0 Zinc-finger double domain Amidohydro_1 PF01979.20 OQS03418.1 - 2.6e-49 168.4 0.5 1.8e-25 90.0 0.3 2.2 1 1 1 2 2 2 2 Amidohydrolase family Amidohydro_3 PF07969.11 OQS03418.1 - 3.6e-15 56.4 1.2 1.2e-11 44.7 0.0 2.4 2 0 0 2 2 2 2 Amidohydrolase family MRP-L46 PF11788.8 OQS03418.1 - 0.00014 22.6 0.3 0.0013 19.5 0.1 2.6 2 0 0 2 2 2 1 39S mitochondrial ribosomal protein L46 NUDIX PF00293.28 OQS03418.1 - 0.0095 16.0 0.0 0.02 14.9 0.0 1.5 1 0 0 1 1 1 1 NUDIX domain Anoctamin PF04547.12 OQS03419.1 - 4.5e-128 427.9 4.8 5.6e-128 427.6 4.8 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel Anoct_dimer PF16178.5 OQS03419.1 - 1.5e-14 54.3 0.3 2.6e-14 53.5 0.3 1.3 1 0 0 1 1 1 1 Dimerisation domain of Ca+-activated chloride-channel, anoctamin RSN1_7TM PF02714.15 OQS03419.1 - 0.016 14.5 4.7 0.044 13.1 4.7 1.7 1 0 0 1 1 1 0 Calcium-dependent channel, 7TM region, putative phosphate DUF2207 PF09972.9 OQS03419.1 - 0.21 10.3 7.0 7.2 5.2 7.0 2.8 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF3040 PF11239.8 OQS03419.1 - 3.3 8.1 4.4 4.3 7.7 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3040) Glyco_hydro_47 PF01532.20 OQS03420.1 - 5.2e-106 355.3 0.0 7e-106 354.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 PA PF02225.22 OQS03420.1 - 7.4e-11 41.9 0.0 1.4e-10 41.0 0.0 1.5 1 0 0 1 1 1 1 PA domain EGF_2 PF07974.13 OQS03421.1 - 1.2e-05 25.5 35.5 0.00025 21.4 15.4 3.9 4 0 0 4 4 4 2 EGF-like domain EGF_Tenascin PF18720.1 OQS03421.1 - 0.011 15.7 43.2 0.055 13.5 11.5 3.9 3 1 0 3 3 3 0 Tenascin EGF domain AP_endonuc_2 PF01261.24 OQS03422.1 - 9.5e-34 116.7 0.0 1.3e-33 116.3 0.0 1.1 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel Ank_2 PF12796.7 OQS03423.1 - 1.1e-29 102.9 0.4 4.2e-13 49.7 0.0 4.8 4 0 0 4 4 4 4 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OQS03423.1 - 1.8e-26 89.3 9.6 0.00027 21.1 0.1 8.4 7 1 1 8 8 8 5 Ankyrin repeat Ank_5 PF13857.6 OQS03423.1 - 2.2e-24 85.2 7.7 7.2e-06 26.2 0.0 7.1 5 1 2 7 7 7 5 Ankyrin repeats (many copies) TIR_2 PF13676.6 OQS03423.1 - 7.7e-23 81.4 0.1 2e-17 63.9 0.0 2.9 3 0 0 3 3 3 2 TIR domain Ank_4 PF13637.6 OQS03423.1 - 5.1e-22 78.0 5.0 8e-05 23.1 0.0 6.3 4 1 2 6 6 6 5 Ankyrin repeats (many copies) Ank PF00023.30 OQS03423.1 - 7.1e-21 73.7 10.2 0.0013 19.1 0.1 7.3 6 0 0 6 6 6 5 Ankyrin repeat UDPGT PF00201.18 OQS03423.1 - 3.1e-15 56.0 0.0 5.4e-15 55.2 0.0 1.3 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase TIR PF01582.20 OQS03423.1 - 3.9e-05 23.5 0.0 0.00013 21.9 0.0 1.8 2 0 0 2 2 2 1 TIR domain DUF1863 PF08937.11 OQS03423.1 - 0.005 17.2 0.0 0.011 16.1 0.0 1.5 1 0 0 1 1 1 1 MTH538 TIR-like domain (DUF1863) Glyco_tran_28_C PF04101.16 OQS03423.1 - 0.024 14.6 0.0 0.047 13.7 0.0 1.4 1 0 0 1 1 1 0 Glycosyltransferase family 28 C-terminal domain GATase PF00117.28 OQS03423.1 - 0.17 11.7 0.0 1.4 8.7 0.0 2.1 2 0 0 2 2 2 0 Glutamine amidotransferase class-I Ribosomal_L30_N PF08079.12 OQS03425.1 - 1.8e-23 82.6 12.1 1.8e-23 82.6 12.1 2.4 3 0 0 3 3 3 1 Ribosomal L30 N-terminal domain Ribosomal_L30 PF00327.20 OQS03425.1 - 1.4e-20 72.9 2.9 1.4e-20 72.9 2.9 1.9 2 0 0 2 2 2 1 Ribosomal protein L30p/L7e Pkinase PF00069.25 OQS03426.1 - 3.2e-69 233.2 0.0 5.9e-69 232.4 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQS03426.1 - 1.3e-29 103.3 0.8 1.7e-27 96.3 0.8 2.3 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 OQS03426.1 - 0.00028 20.3 0.4 0.00047 19.6 0.4 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 OQS03426.1 - 0.00052 19.1 0.3 0.0024 16.9 0.3 1.9 2 0 0 2 2 2 1 Haspin like kinase domain Kinase-like PF14531.6 OQS03426.1 - 0.062 12.6 0.0 0.38 10.0 0.0 2.2 3 0 0 3 3 3 0 Kinase-like APH PF01636.23 OQS03426.1 - 0.081 12.8 0.1 0.13 12.2 0.1 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 OQS03426.1 - 0.089 11.6 0.6 0.15 10.8 0.0 1.6 2 0 0 2 2 2 0 Fungal protein kinase YukC PF10140.9 OQS03426.1 - 0.096 11.5 0.0 0.15 10.9 0.0 1.2 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukC MatE PF01554.18 OQS03427.1 - 1.7e-44 151.3 29.6 5.2e-25 88.0 10.9 2.4 2 0 0 2 2 2 2 MatE Adeno_E3_CR2 PF02439.15 OQS03427.1 - 0.028 14.2 0.7 0.028 14.2 0.7 3.3 4 0 0 4 4 4 0 Adenovirus E3 region protein CR2 RNA_pol_I_A49 PF06870.12 OQS03428.1 - 6.1e-74 249.2 3.5 7.2e-74 249.0 3.5 1.0 1 0 0 1 1 1 1 A49-like RNA polymerase I associated factor ISG65-75 PF11727.8 OQS03428.1 - 0.15 11.2 3.2 0.27 10.4 3.2 1.4 1 0 0 1 1 1 0 Invariant surface glycoprotein Ribosomal_L14e PF01929.17 OQS03429.1 - 2.1e-29 101.8 6.4 3.4e-29 101.1 6.4 1.4 1 0 0 1 1 1 1 Ribosomal protein L14 KOW PF00467.29 OQS03429.1 - 0.055 13.4 0.0 0.14 12.1 0.0 1.9 1 1 0 1 1 1 0 KOW motif Rcd1 PF04078.13 OQS03430.1 - 1.4e-127 424.4 1.4 1.6e-127 424.2 1.4 1.0 1 0 0 1 1 1 1 Cell differentiation family, Rcd1-like Ribo_biogen_C PF04034.13 OQS03431.1 - 2.3e-51 172.8 0.1 3.8e-51 172.1 0.1 1.4 1 0 0 1 1 1 1 Ribosome biogenesis protein, C-terminal RLI PF04068.15 OQS03431.1 - 1.8e-09 37.3 0.3 3e-09 36.5 0.3 1.4 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI Peptidase_S64 PF08192.11 OQS03431.1 - 5.4 5.4 7.0 7.4 4.9 7.0 1.1 1 0 0 1 1 1 0 Peptidase family S64 Ribosomal_L5e PF17144.4 OQS03432.1 - 3.3e-81 271.1 2.2 3.3e-81 271.1 2.2 1.6 2 0 0 2 2 2 1 Ribosomal large subunit proteins 60S L5, and 50S L18 Ribosomal_L18_c PF14204.6 OQS03432.1 - 1.5e-29 102.8 6.6 1.5e-29 102.8 6.6 2.1 2 0 0 2 2 2 1 Ribosomal L18 C-terminal region FAD_binding_3 PF01494.19 OQS03434.1 - 2.8e-87 293.2 0.1 2.8e-68 230.7 0.0 2.3 2 1 0 2 2 2 2 FAD binding domain DAO PF01266.24 OQS03434.1 - 4.3e-09 36.4 0.3 0.00019 21.1 0.4 2.4 1 1 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 OQS03434.1 - 1.4e-06 27.8 0.8 0.024 13.9 0.1 2.4 1 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 OQS03434.1 - 2.1e-05 24.0 0.0 2.9e-05 23.6 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 OQS03434.1 - 0.0001 21.7 0.0 0.00025 20.4 0.0 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OQS03434.1 - 0.00015 21.9 0.0 0.00045 20.4 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 OQS03434.1 - 0.00077 18.8 0.1 0.0016 17.8 0.1 1.4 1 0 0 1 1 1 1 Thi4 family Shikimate_DH PF01488.20 OQS03434.1 - 0.0012 18.9 0.0 0.0022 18.1 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase FAD_binding_2 PF00890.24 OQS03434.1 - 0.0021 17.2 0.4 0.0036 16.5 0.2 1.5 2 0 0 2 2 2 1 FAD binding domain Lycopene_cycl PF05834.12 OQS03434.1 - 0.0022 17.1 0.0 0.0044 16.1 0.0 1.5 1 0 0 1 1 1 1 Lycopene cyclase protein ThiF PF00899.21 OQS03434.1 - 0.004 16.5 0.0 0.0081 15.5 0.0 1.4 1 0 0 1 1 1 1 ThiF family Pyr_redox PF00070.27 OQS03434.1 - 0.019 15.5 0.2 7.8 7.1 0.1 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 OQS03434.1 - 0.024 14.7 0.2 0.084 12.9 0.1 1.9 2 0 0 2 2 2 0 FAD-NAD(P)-binding HI0933_like PF03486.14 OQS03434.1 - 0.027 13.2 0.1 0.47 9.1 0.1 2.1 2 0 0 2 2 2 0 HI0933-like protein Hydrolase_like PF13242.6 OQS03434.1 - 0.037 14.1 0.0 14 5.8 0.0 2.5 2 0 0 2 2 2 0 HAD-hyrolase-like TrkA_N PF02254.18 OQS03434.1 - 0.076 13.3 0.2 0.15 12.3 0.2 1.4 1 0 0 1 1 1 0 TrkA-N domain Sacchrp_dh_NADP PF03435.18 OQS03434.1 - 0.13 12.6 0.0 0.25 11.6 0.0 1.5 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Trp_halogenase PF04820.14 OQS03434.1 - 0.63 8.8 4.6 6.4 5.5 0.3 2.5 2 1 0 3 3 3 0 Tryptophan halogenase PseudoU_synth_1 PF01416.20 OQS03435.1 - 2.2e-17 63.5 0.0 6e-13 49.2 0.0 2.3 2 0 0 2 2 2 2 tRNA pseudouridine synthase DUF2344 PF10105.9 OQS03435.1 - 0.00021 21.2 0.0 0.00038 20.3 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2344) PurK_C PF17769.1 OQS03435.1 - 0.18 11.5 2.6 0.41 10.4 2.6 1.6 1 0 0 1 1 1 0 Phosphoribosylaminoimidazole carboxylase C-terminal domain Trypsin PF00089.26 OQS03437.1 - 1.2e-49 169.1 1.9 1.4e-49 168.9 1.9 1.0 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 OQS03437.1 - 1.9e-05 25.6 0.1 3.1e-05 24.9 0.1 1.3 1 0 0 1 1 1 1 Trypsin-like peptidase domain Kazal_2 PF07648.15 OQS03438.1 - 2.9e-24 84.9 31.3 2e-09 37.4 5.1 3.3 2 1 1 3 3 3 3 Kazal-type serine protease inhibitor domain Kazal_1 PF00050.21 OQS03438.1 - 3e-22 78.4 31.2 4.9e-09 36.1 5.4 3.3 1 1 2 3 3 3 3 Kazal-type serine protease inhibitor domain Aconitase PF00330.20 OQS03439.1 - 5.1e-70 236.8 0.2 4e-68 230.5 0.2 2.1 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 OQS03439.1 - 1.2e-17 64.5 0.0 2.2e-17 63.6 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain Rod_cone_degen PF15201.6 OQS03439.1 - 0.046 13.8 0.0 0.11 12.6 0.0 1.6 1 0 0 1 1 1 0 Progressive rod-cone degeneration RCC1 PF00415.18 OQS03440.1 - 1.7e-36 124.6 17.7 3.5e-12 46.7 0.9 5.5 5 0 0 5 5 5 3 Regulator of chromosome condensation (RCC1) repeat EF-hand_6 PF13405.6 OQS03440.1 - 4.1e-20 69.9 9.8 2.6e-05 23.8 0.1 5.2 5 0 0 5 5 5 4 EF-hand domain EF-hand_1 PF00036.32 OQS03440.1 - 4.1e-19 66.6 17.8 3.1e-06 26.3 0.1 5.0 5 0 0 5 5 5 4 EF hand RCC1_2 PF13540.6 OQS03440.1 - 9.1e-15 54.0 18.2 0.031 14.1 0.0 6.3 6 0 0 6 6 6 5 Regulator of chromosome condensation (RCC1) repeat EF-hand_7 PF13499.6 OQS03440.1 - 9.1e-14 51.7 11.3 2.3e-07 31.2 0.6 4.1 3 1 0 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.6 OQS03440.1 - 2.2e-12 45.9 15.0 0.0021 17.4 0.4 4.9 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.6 OQS03440.1 - 7.1e-10 38.6 8.1 0.0061 16.4 0.2 3.9 3 1 1 4 4 4 3 EF-hand domain pair EF-hand_10 PF14788.6 OQS03440.1 - 3.4e-09 36.4 2.5 1.6e-07 31.1 0.6 3.0 2 0 0 2 2 2 1 EF hand EF-hand_9 PF14658.6 OQS03440.1 - 0.0046 17.3 0.1 8.2 6.8 0.0 3.4 2 1 0 2 2 2 1 EF-hand domain EF-hand_14 PF17959.1 OQS03440.1 - 0.0048 17.2 0.8 1.2 9.6 0.1 2.9 2 0 0 2 2 2 1 EF-hand domain SPARC_Ca_bdg PF10591.9 OQS03440.1 - 0.019 15.3 1.7 0.052 13.9 0.3 2.6 2 0 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region DUF2868 PF11067.8 OQS03440.1 - 0.059 12.9 1.2 0.079 12.5 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2868) Kelch_6 PF13964.6 OQS03440.1 - 0.72 10.2 7.4 26 5.3 0.1 4.3 5 0 0 5 5 4 0 Kelch motif Caleosin PF05042.13 OQS03440.1 - 2.5 8.0 4.1 63 3.4 0.0 3.8 3 1 1 4 4 4 0 Caleosin related protein Methyltransf_5 PF01795.19 OQS03442.1 - 5.2e-93 311.9 0.0 7.3e-93 311.4 0.0 1.2 1 0 0 1 1 1 1 MraW methylase family DIM1 PF02966.16 OQS03442.1 - 2e-48 163.5 0.5 3.7e-48 162.7 0.5 1.4 1 0 0 1 1 1 1 Mitosis protein DIM1 PH PF00169.29 OQS03442.1 - 1.7e-08 34.9 0.1 1.8e-07 31.6 0.0 2.6 3 0 0 3 3 3 1 PH domain Methyltransf_31 PF13847.6 OQS03442.1 - 0.0072 16.1 0.0 0.084 12.7 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 OQS03442.1 - 0.047 14.4 0.0 0.18 12.5 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase domain CRCB PF02537.15 OQS03443.1 - 1.2e-32 112.0 22.6 2.3e-18 66.3 3.5 2.8 3 0 0 3 3 3 2 CrcB-like protein, Camphor Resistance (CrcB) DUF2878 PF11086.8 OQS03443.1 - 0.014 15.6 1.6 0.014 15.6 1.6 3.4 2 2 1 4 4 4 0 Protein of unknown function (DUF2878) Collectrin PF16959.5 OQS03443.1 - 0.016 15.0 0.0 0.032 14.0 0.0 1.5 1 0 0 1 1 1 0 Renal amino acid transporter Tetraspanin PF00335.20 OQS03443.1 - 0.38 10.4 12.3 1.5 8.5 1.1 3.3 2 1 1 3 3 3 0 Tetraspanin family RseC_MucC PF04246.12 OQS03443.1 - 3.2 7.7 8.2 0.16 11.9 1.0 2.5 3 0 0 3 3 3 0 Positive regulator of sigma(E), RseC/MucC UDPG_MGDP_dh_N PF03721.14 OQS03444.1 - 1.1e-60 204.4 0.1 2.7e-60 203.1 0.1 1.7 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh PF00984.19 OQS03444.1 - 4.6e-32 110.1 0.0 1.2e-31 108.8 0.0 1.8 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain UDPG_MGDP_dh_C PF03720.15 OQS03444.1 - 2.4e-28 98.6 0.7 6.6e-26 90.8 0.2 3.1 3 0 0 3 3 3 1 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain Snf7 PF03357.21 OQS03444.1 - 6.3e-14 51.9 7.2 1.1e-13 51.2 7.2 1.3 1 0 0 1 1 1 1 Snf7 Ist1 PF03398.14 OQS03444.1 - 0.012 15.5 1.2 0.024 14.6 1.2 1.5 1 0 0 1 1 1 0 Regulator of Vps4 activity in the MVB pathway ApbA PF02558.16 OQS03444.1 - 0.053 13.2 0.0 0.11 12.1 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Cytochrom_B562 PF07361.11 OQS03444.1 - 0.17 12.5 6.2 0.11 13.1 1.4 2.6 2 0 0 2 2 2 0 Cytochrome b562 OTCace PF00185.24 OQS03444.1 - 1.4 9.0 5.7 2.3 8.3 0.1 3.3 3 1 0 3 3 3 0 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain NAD_binding_2 PF03446.15 OQS03444.1 - 1.5 9.0 5.2 1.6 8.9 0.3 3.4 3 1 0 3 3 3 0 NAD binding domain of 6-phosphogluconate dehydrogenase LSM PF01423.22 OQS03445.1 - 6.6e-21 73.8 0.0 7.6e-21 73.6 0.0 1.1 1 0 0 1 1 1 1 LSM domain DUF150_C PF17384.2 OQS03445.1 - 0.041 14.0 0.0 0.1 12.7 0.1 1.6 2 0 0 2 2 2 0 RimP C-terminal SH3 domain Glyco_transf_41 PF13844.6 OQS03446.1 - 1.6e-78 264.3 1.9 8.6e-39 133.3 0.5 2.1 1 1 1 2 2 2 2 Glycosyl transferase family 41 TPR_2 PF07719.17 OQS03446.1 - 2.4e-14 52.2 17.8 0.009 16.1 0.1 6.8 7 0 0 7 7 6 5 Tetratricopeptide repeat TPR_1 PF00515.28 OQS03446.1 - 5.7e-11 41.7 14.7 0.0056 16.4 0.2 5.9 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_11 PF13414.6 OQS03446.1 - 8e-09 35.1 17.3 1.4e-05 24.7 0.8 4.2 2 1 1 3 3 3 2 TPR repeat TPR_17 PF13431.6 OQS03446.1 - 3.1e-07 30.3 13.1 0.014 15.8 0.1 4.6 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_19 PF14559.6 OQS03446.1 - 2.9e-06 27.7 5.9 0.027 15.0 0.1 4.4 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 OQS03446.1 - 3.3e-06 27.3 21.3 0.0029 17.8 0.4 5.2 5 1 0 5 5 5 3 Tetratricopeptide repeat TPR_7 PF13176.6 OQS03446.1 - 1.5e-05 24.7 5.8 0.38 10.9 0.0 5.4 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.6 OQS03446.1 - 2.7e-05 24.7 8.1 0.91 10.2 0.1 5.1 3 1 2 5 5 5 3 Tetratricopeptide repeat TPR_14 PF13428.6 OQS03446.1 - 0.00059 20.4 3.7 2.4 9.2 0.1 5.0 2 1 3 5 5 5 2 Tetratricopeptide repeat TPR_8 PF13181.6 OQS03446.1 - 0.0077 16.4 7.8 13 6.3 0.0 5.7 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_9 PF13371.6 OQS03446.1 - 0.01 16.0 1.1 3.7 7.8 0.0 3.2 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.6 OQS03446.1 - 0.035 14.7 1.0 29 5.6 0.0 4.7 5 0 0 5 5 5 0 Tetratricopeptide repeat zf-ANAPC11 PF12861.7 OQS03447.1 - 6.8e-36 122.2 13.9 7.5e-36 122.1 13.9 1.0 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 OQS03447.1 - 3.3e-21 75.3 19.3 4.3e-21 74.9 19.3 1.1 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 OQS03447.1 - 3.3e-05 24.1 21.6 0.00038 20.7 21.6 2.1 1 1 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 OQS03447.1 - 0.01 15.8 8.8 0.026 14.5 6.9 2.1 1 1 1 2 2 2 0 RING-type zinc-finger FANCL_C PF11793.8 OQS03447.1 - 0.027 14.6 18.4 0.085 13.0 18.4 2.0 1 1 0 1 1 1 0 FANCL C-terminal domain Rad50_zn_hook PF04423.14 OQS03447.1 - 0.17 11.7 0.3 0.17 11.7 0.3 2.6 2 1 1 3 3 3 0 Rad50 zinc hook motif zf-C3HC4 PF00097.25 OQS03447.1 - 0.27 11.2 21.9 0.88 9.5 20.4 2.4 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OQS03447.1 - 4.1 7.4 23.0 2.6e+02 1.7 23.6 2.7 1 1 1 2 2 2 0 zinc-RING finger domain zf-C3HC4_3 PF13920.6 OQS03447.1 - 6.4 6.7 21.5 1.1 9.2 13.0 2.3 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Mod_r PF07200.13 OQS03448.1 - 5.4e-32 110.9 5.0 7.3e-32 110.5 5.0 1.2 1 0 0 1 1 1 1 Modifier of rudimentary (Mod(r)) protein UQ_con PF00179.26 OQS03448.1 - 0.00045 19.9 0.0 0.00099 18.8 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Tropomyosin_1 PF12718.7 OQS03448.1 - 0.01 16.0 2.4 0.016 15.3 2.4 1.2 1 0 0 1 1 1 1 Tropomyosin like Herpes_UL6 PF01763.16 OQS03448.1 - 0.01 14.4 1.1 0.014 13.9 1.1 1.1 1 0 0 1 1 1 0 Herpesvirus UL6 like ADIP PF11559.8 OQS03448.1 - 0.028 14.5 3.1 0.043 13.9 3.1 1.3 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding Gp-FAR-1 PF05823.12 OQS03448.1 - 0.05 13.9 1.1 0.094 13.1 1.1 1.4 1 0 0 1 1 1 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) Prefoldin_2 PF01920.20 OQS03448.1 - 0.37 10.8 6.2 7.8 6.5 0.1 2.6 2 1 1 3 3 3 0 Prefoldin subunit TRAF_BIRC3_bd PF16673.5 OQS03448.1 - 0.42 10.4 4.4 0.089 12.6 0.7 1.8 2 0 0 2 2 2 0 TNF receptor-associated factor BIRC3 binding domain DUF4795 PF16043.5 OQS03448.1 - 0.65 9.6 5.3 1.6 8.2 3.4 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4795) TPR_2 PF07719.17 OQS03449.1 - 1.7e-11 43.3 14.3 0.075 13.2 0.2 7.9 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_1 PF00515.28 OQS03449.1 - 9e-11 41.1 10.8 0.0036 17.1 0.1 6.9 6 1 1 7 7 7 2 Tetratricopeptide repeat TPR_9 PF13371.6 OQS03449.1 - 3.4e-07 30.3 7.3 0.039 14.1 0.3 5.3 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_16 PF13432.6 OQS03449.1 - 0.00062 20.4 5.9 0.0013 19.4 0.2 4.1 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_14 PF13428.6 OQS03449.1 - 0.0089 16.8 7.6 0.08 13.8 0.3 4.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.6 OQS03449.1 - 0.035 14.4 10.2 1.8 8.9 0.4 6.3 6 1 1 7 7 7 0 Tetratricopeptide repeat TPR_7 PF13176.6 OQS03449.1 - 0.054 13.6 6.2 30 4.9 0.0 5.0 5 1 0 5 5 5 0 Tetratricopeptide repeat TPR_11 PF13414.6 OQS03449.1 - 0.092 12.4 5.9 1.1 8.9 0.1 4.1 5 0 0 5 5 5 0 TPR repeat ANAPC3 PF12895.7 OQS03449.1 - 0.3 11.3 8.8 7.4 6.9 0.2 3.3 2 1 1 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 Aa_trans PF01490.18 OQS03451.1 - 1e-57 195.7 41.8 1.3e-57 195.4 41.8 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 OQS03451.1 - 1.4e-07 31.0 22.9 1.4e-07 31.0 22.9 2.1 2 0 0 2 2 2 1 Tryptophan/tyrosine permease family ITAM PF02189.15 OQS03451.1 - 2 9.1 3.4 29 5.4 0.0 2.8 3 0 0 3 3 3 0 Immunoreceptor tyrosine-based activation motif PP2C PF00481.21 OQS03452.1 - 3.2e-52 177.7 0.0 7.4e-51 173.3 0.0 2.1 1 1 0 1 1 1 1 Protein phosphatase 2C PH PF00169.29 OQS03452.1 - 2.2e-12 47.4 0.1 6.1e-12 46.0 0.1 1.8 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 OQS03452.1 - 2.6e-05 24.6 0.4 7.8e-05 23.0 0.4 1.8 1 1 0 1 1 1 1 Pleckstrin homology domain PH_9 PF15410.6 OQS03452.1 - 0.0018 18.6 0.6 0.0056 17.0 0.1 2.1 3 0 0 3 3 3 1 Pleckstrin homology domain PP2C_2 PF13672.6 OQS03452.1 - 0.046 13.3 0.0 0.086 12.5 0.0 1.4 1 0 0 1 1 1 0 Protein phosphatase 2C SKN1 PF03935.15 OQS03453.1 - 2.6e-44 151.5 13.4 1.7e-27 96.0 2.6 3.4 2 2 0 2 2 2 2 Beta-glucan synthesis-associated protein (SKN1) zf-CCCH PF00642.24 OQS03455.1 - 0.00048 20.0 6.9 0.0012 18.7 6.9 1.7 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) tRNA_anti-codon PF01336.25 OQS03455.1 - 0.014 15.4 0.1 0.028 14.4 0.1 1.5 1 0 0 1 1 1 0 OB-fold nucleic acid binding domain zf-CCCH_3 PF15663.5 OQS03455.1 - 0.023 14.9 0.7 0.069 13.4 0.7 1.8 1 0 0 1 1 1 0 Zinc-finger containing family Ubie_methyltran PF01209.18 OQS03455.1 - 0.14 11.5 0.0 0.26 10.6 0.0 1.4 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family SDF PF00375.18 OQS03456.1 - 5.9e-100 335.0 52.0 3.2e-72 243.7 27.1 3.0 2 2 0 2 2 2 2 Sodium:dicarboxylate symporter family Gly-zipper_Omp PF13488.6 OQS03456.1 - 0.00041 20.3 8.0 0.092 12.8 1.1 2.5 2 0 0 2 2 2 2 Glycine zipper Fascin PF06268.13 OQS03456.1 - 0.0057 16.9 0.0 1.6 9.0 0.0 2.3 2 0 0 2 2 2 2 Fascin domain TPP_enzyme_C PF02775.21 OQS03456.1 - 0.006 16.4 0.9 3.1 7.6 0.1 3.1 3 0 0 3 3 3 2 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain DUF4514 PF14986.6 OQS03456.1 - 0.4 10.7 4.1 5.4 7.1 0.4 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4514) Gly-zipper_YMGG PF13441.6 OQS03456.1 - 0.48 10.2 13.3 3 7.6 4.0 2.3 2 0 0 2 2 2 0 YMGG-like Gly-zipper Rick_17kDa_Anti PF05433.15 OQS03456.1 - 0.93 9.4 14.0 2.1 8.3 4.3 2.3 2 0 0 2 2 2 0 Glycine zipper 2TM domain SDF PF00375.18 OQS03458.1 - 1.4e-65 221.9 38.2 6.8e-65 219.6 38.2 1.8 1 1 0 1 1 1 1 Sodium:dicarboxylate symporter family SDF PF00375.18 OQS03459.1 - 1.5e-210 699.2 130.7 1.9e-70 237.9 36.6 5.0 3 3 0 3 3 3 3 Sodium:dicarboxylate symporter family Fascin PF06268.13 OQS03459.1 - 0.00018 21.7 0.0 0.1 12.9 0.0 2.4 2 0 0 2 2 2 2 Fascin domain DUF5313 PF17240.2 OQS03459.1 - 0.3 11.5 9.1 36 4.8 0.1 4.8 4 0 0 4 4 4 0 Family of unknown function (DUF5313) PRMT5 PF05185.16 OQS03460.1 - 8.3e-69 230.9 0.0 1.2e-68 230.4 0.0 1.2 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase PRMT5_TIM PF17285.2 OQS03460.1 - 7.8e-67 225.2 0.0 1.3e-66 224.4 0.0 1.3 1 0 0 1 1 1 1 PRMT5 TIM barrel domain PRMT5_C PF17286.2 OQS03460.1 - 1.2e-55 188.1 0.2 2.1e-55 187.3 0.2 1.4 1 0 0 1 1 1 1 PRMT5 oligomerisation domain Methyltransf_31 PF13847.6 OQS03460.1 - 0.0096 15.7 0.0 0.018 14.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.16 OQS03460.1 - 0.049 13.4 0.0 0.076 12.8 0.0 1.2 1 0 0 1 1 1 0 Met-10+ like-protein HELP PF03451.14 OQS03461.1 - 0.097 12.5 0.2 0.33 10.8 0.0 2.0 2 1 0 2 2 2 0 HELP motif PRCC PF10253.9 OQS03461.1 - 0.3 11.8 7.4 0.4 11.5 7.4 1.3 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting DUF2076 PF09849.9 OQS03461.1 - 0.41 10.7 5.9 0.63 10.0 5.9 1.5 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) SOG2 PF10428.9 OQS03461.1 - 1.9 7.6 12.3 1.8 7.7 12.3 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Ricin_B_lectin PF00652.22 OQS03462.1 - 1.1e-09 38.7 1.8 2e-08 34.5 0.2 2.7 2 1 1 3 3 3 1 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.6 OQS03462.1 - 0.00057 20.6 0.1 0.063 14.0 0.0 2.8 2 1 0 2 2 2 1 Ricin-type beta-trefoil lectin domain-like CDtoxinA PF03498.14 OQS03462.1 - 0.038 13.6 1.3 0.079 12.5 0.1 2.1 3 0 0 3 3 3 0 Cytolethal distending toxin A/C domain Acetyltransf_4 PF13420.7 OQS03462.1 - 0.067 13.3 0.0 0.14 12.3 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain zf-Tim10_DDP PF02953.15 OQS03463.1 - 0.074 12.7 2.7 0.13 12.0 1.5 2.0 2 0 0 2 2 2 0 Tim10/DDP family zinc finger Treacle PF03546.14 OQS03463.1 - 0.36 9.6 7.5 0.53 9.1 7.5 1.1 1 0 0 1 1 1 0 Treacher Collins syndrome protein Treacle DDE_Tnp_4 PF13359.6 OQS03464.1 - 7.5e-11 42.0 0.0 9.6e-11 41.6 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_1 PF01609.21 OQS03464.1 - 0.0012 18.6 0.0 0.0028 17.4 0.0 1.5 1 1 1 2 2 2 1 Transposase DDE domain Caprin-1_dimer PF18293.1 OQS03466.1 - 0.0047 17.4 0.0 0.006 17.1 0.0 1.1 1 0 0 1 1 1 1 Caprin-1 dimerization domain LytR_C PF13399.6 OQS03466.1 - 0.033 15.2 0.0 0.038 15.0 0.0 1.2 1 0 0 1 1 1 0 LytR cell envelope-related transcriptional attenuator Siva PF05458.12 OQS03467.1 - 0.023 14.4 1.0 0.059 13.0 1.0 1.6 1 0 0 1 1 1 0 Cd27 binding protein (Siva) C1_1 PF00130.22 OQS03467.1 - 0.88 9.5 6.0 0.31 11.0 1.9 2.2 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Fer4_22 PF17179.4 OQS03467.1 - 1.4 9.8 7.3 0.14 13.0 1.3 2.5 2 0 0 2 2 2 0 4Fe-4S dicluster domain zf-HC5HC2H_2 PF13832.6 OQS03467.1 - 2.4 8.4 9.1 2.8 8.1 1.7 2.5 2 0 0 2 2 2 0 PHD-zinc-finger like domain Zf_RING PF16744.5 OQS03467.1 - 7.1 6.8 8.9 0.25 11.5 2.1 2.1 2 0 0 2 2 2 0 KIAA1045 RING finger PHF5 PF03660.14 OQS03467.1 - 9 6.6 8.2 0.55 10.5 0.4 2.4 2 0 0 2 2 2 0 PHF5-like protein ArsC PF03960.15 OQS03468.1 - 1.1e-11 44.6 0.0 1.5e-11 44.1 0.0 1.3 1 0 0 1 1 1 1 ArsC family RRM_1 PF00076.22 OQS03469.1 - 8.7e-52 172.8 0.0 1.1e-15 57.2 0.0 3.1 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 OQS03469.1 - 1.6e-10 41.0 0.1 0.031 14.4 0.0 3.5 3 0 0 3 3 3 3 RNA recognition motif RRM_occluded PF16842.5 OQS03469.1 - 2.1e-08 33.9 0.0 0.002 18.0 0.0 3.1 3 0 0 3 3 3 2 Occluded RNA-recognition motif PHM7_cyt PF14703.6 OQS03469.1 - 3.3e-06 27.5 0.6 2 8.6 0.0 4.7 3 2 2 5 5 5 1 Cytosolic domain of 10TM putative phosphate transporter Nup35_RRM_2 PF14605.6 OQS03469.1 - 6.3e-06 26.1 0.0 0.0035 17.3 0.0 3.3 3 0 0 3 3 3 1 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.11 OQS03469.1 - 0.00015 21.8 0.0 0.1 12.7 0.0 2.9 3 0 0 3 3 3 1 RNA binding motif RRM_Rrp7 PF17799.1 OQS03469.1 - 0.00024 20.9 0.9 0.19 11.5 0.1 3.4 1 1 1 3 3 3 1 Rrp7 RRM-like N-terminal domain Nup35_RRM PF05172.13 OQS03469.1 - 0.0016 18.3 0.0 0.12 12.3 0.1 3.2 2 2 0 2 2 2 1 Nup53/35/40-type RNA recognition motif bPH_2 PF03703.14 OQS03469.1 - 0.0087 16.2 0.0 4.4 7.6 0.0 2.4 2 0 0 2 2 2 2 Bacterial PH domain RimM PF01782.18 OQS03469.1 - 0.093 13.0 0.0 4.2 7.6 0.0 2.8 3 0 0 3 3 3 0 RimM N-terminal domain Glyoxalase PF00903.25 OQS03469.1 - 0.11 12.7 0.1 0.19 11.9 0.1 1.4 1 0 0 1 1 1 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Arm PF00514.23 OQS03470.1 - 2.1e-234 751.6 182.0 4.6e-09 36.0 0.0 72.7 75 0 0 75 75 72 45 Armadillo/beta-catenin-like repeat Aquarius_N PF16399.5 OQS03470.1 - 3.9e-149 498.2 0.0 6.3e-149 497.5 0.0 1.2 1 0 0 1 1 1 1 Intron-binding protein aquarius N-terminus HEAT_2 PF13646.6 OQS03470.1 - 5.2e-37 126.1 95.2 0.0049 17.2 0.5 30.6 22 9 9 32 32 31 10 HEAT repeats Arm_2 PF04826.13 OQS03470.1 - 1.2e-32 113.4 46.8 0.00036 20.1 0.0 20.2 7 2 13 24 24 24 11 Armadillo-like ENTH PF01417.20 OQS03470.1 - 1.6e-32 112.2 0.2 3.9e-32 110.9 0.2 1.8 1 0 0 1 1 1 1 ENTH domain AAA_12 PF13087.6 OQS03470.1 - 5.4e-22 78.4 0.0 1.2e-21 77.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain Lipase_3 PF01764.25 OQS03470.1 - 9.8e-18 64.4 0.0 3.7e-17 62.5 0.0 2.0 1 0 0 1 1 1 1 Lipase (class 3) FYVE PF01363.21 OQS03470.1 - 1.3e-17 63.7 19.8 1.4e-10 41.2 11.8 2.8 2 0 0 2 2 2 2 FYVE zinc finger HEAT_EZ PF13513.6 OQS03470.1 - 5e-17 62.0 110.6 0.00098 19.6 0.1 28.2 28 5 6 34 34 28 4 HEAT-like repeat KAP PF05804.12 OQS03470.1 - 6.6e-17 60.9 8.4 0.021 13.0 0.3 10.4 9 2 1 11 11 11 5 Kinesin-associated protein (KAP) V-ATPase_H_N PF03224.14 OQS03470.1 - 1.6e-15 57.2 17.7 1.6 7.9 0.2 14.5 7 4 3 11 11 11 5 V-ATPase subunit H AAA_11 PF13086.6 OQS03470.1 - 1.1e-09 38.4 0.2 1.9e-05 24.6 0.0 3.7 4 0 0 4 4 2 2 AAA domain Cnd1 PF12717.7 OQS03470.1 - 1.7e-08 34.7 26.6 0.23 11.5 0.0 12.8 11 4 2 13 13 12 1 non-SMC mitotic condensation complex subunit 1 Atx10homo_assoc PF09759.9 OQS03470.1 - 9.8e-06 25.5 23.5 1.8 8.6 0.0 13.3 15 1 2 17 17 12 1 Spinocerebellar ataxia type 10 protein domain AAA_30 PF13604.6 OQS03470.1 - 0.00011 21.9 0.6 0.001 18.8 0.0 2.7 3 0 0 3 3 3 1 AAA domain AAA_19 PF13245.6 OQS03470.1 - 0.00015 22.1 0.0 0.00056 20.3 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 OQS03470.1 - 0.00021 21.5 0.1 0.0011 19.2 0.0 2.3 2 0 0 2 2 1 1 AAA domain AAA_16 PF13191.6 OQS03470.1 - 0.00069 20.0 0.0 0.0035 17.7 0.0 2.3 1 0 0 1 1 1 1 AAA ATPase domain Abhydrolase_3 PF07859.13 OQS03470.1 - 0.00082 19.3 0.6 0.0041 17.0 0.1 2.3 2 0 0 2 2 2 1 alpha/beta hydrolase fold WAPL PF07814.13 OQS03470.1 - 0.004 16.0 16.4 0.052 12.3 0.2 6.8 5 2 1 6 6 6 1 Wings apart-like protein regulation of heterochromatin cobW PF02492.19 OQS03470.1 - 0.004 16.8 0.0 0.014 15.0 0.0 2.0 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain ResIII PF04851.15 OQS03470.1 - 0.0045 17.0 0.0 0.011 15.7 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Nipped-B_C PF12830.7 OQS03470.1 - 0.0047 16.9 4.4 11 5.9 0.0 6.2 6 0 0 6 6 5 0 Sister chromatid cohesion C-terminus Hydrolase_4 PF12146.8 OQS03470.1 - 0.022 14.0 0.0 0.056 12.7 0.0 1.6 1 0 0 1 1 1 0 Serine aminopeptidase, S33 UvrD-helicase PF00580.21 OQS03470.1 - 0.047 13.2 0.0 0.13 11.7 0.0 1.8 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain C5HCH PF17982.1 OQS03470.1 - 0.058 13.5 1.8 0.29 11.3 1.8 2.3 1 0 0 1 1 1 0 NSD Cys-His rich domain Adeno_IVa2 PF02456.15 OQS03470.1 - 0.06 12.1 0.0 0.19 10.5 0.0 1.7 2 0 0 2 2 2 0 Adenovirus IVa2 protein RNA_polI_A34 PF08208.11 OQS03470.1 - 0.1 12.7 4.6 0.19 11.8 4.6 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 AAA_33 PF13671.6 OQS03470.1 - 0.15 12.2 0.0 0.6 10.3 0.0 2.1 1 0 0 1 1 1 0 AAA domain NopRA1 PF16201.5 OQS03470.1 - 0.48 10.0 16.8 8.9 5.8 0.1 8.6 8 2 1 9 9 7 0 Nucleolar pre-ribosomal-associated protein 1 UNC45-central PF11701.8 OQS03470.1 - 0.52 10.3 29.0 6.1 6.8 0.2 9.2 10 1 0 10 10 8 0 Myosin-binding striated muscle assembly central ATP-synt_E PF05680.12 OQS03470.1 - 9.2 6.7 7.1 6.6 7.2 2.3 3.4 3 0 0 3 3 1 0 ATP synthase E chain Abhydrolase_6 PF12697.7 OQS03470.1 - 9.5 6.7 9.1 0.6 10.7 0.1 3.2 2 0 0 2 2 1 0 Alpha/beta hydrolase family Ion_trans_2 PF07885.16 OQS03473.1 - 6.5e-10 38.8 2.9 1.1e-05 25.3 0.1 2.7 2 0 0 2 2 2 2 Ion channel IRK PF01007.20 OQS03473.1 - 0.0015 18.3 0.1 0.33 10.8 0.0 2.3 2 0 0 2 2 2 2 Inward rectifier potassium channel transmembrane domain IRK_C PF17655.1 OQS03473.1 - 0.13 11.9 0.0 2.5 7.7 0.0 2.1 1 1 1 2 2 2 0 Inward rectifier potassium channel C-terminal domain IRK_C PF17655.1 OQS03474.1 - 1.3e-13 51.0 0.3 3.9e-12 46.1 0.0 2.2 2 0 0 2 2 2 1 Inward rectifier potassium channel C-terminal domain Ion_trans_2 PF07885.16 OQS03474.1 - 2.3e-09 37.1 18.2 5.4e-05 23.1 3.8 3.0 2 2 0 2 2 2 2 Ion channel IRK PF01007.20 OQS03474.1 - 0.00016 21.5 25.2 0.00049 19.9 3.6 4.0 2 2 1 3 3 3 2 Inward rectifier potassium channel transmembrane domain DUF2207 PF09972.9 OQS03474.1 - 8.8 5.0 6.6 7.5 5.2 0.1 2.1 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) IRK_C PF17655.1 OQS03475.1 - 1.5e-08 34.4 0.1 1.8e-08 34.2 0.1 1.1 1 0 0 1 1 1 1 Inward rectifier potassium channel C-terminal domain Cons_hypoth95 PF03602.15 OQS03475.1 - 0.14 11.7 0.0 0.19 11.4 0.0 1.1 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Tubulin PF00091.25 OQS03476.1 - 1.7e-64 217.7 0.0 2.4e-64 217.2 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 OQS03476.1 - 5.3e-50 168.8 0.1 8.3e-50 168.2 0.1 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 OQS03476.1 - 0.0045 16.7 0.0 0.015 15.0 0.0 1.9 3 0 0 3 3 3 1 Tubulin domain Ribosomal_L38e PF01781.18 OQS03477.1 - 6.2e-34 115.9 4.5 6.8e-34 115.8 4.5 1.0 1 0 0 1 1 1 1 Ribosomal L38e protein family Pkinase_Tyr PF07714.17 OQS03478.1 - 1.5e-18 67.0 0.0 4.4e-18 65.5 0.0 1.8 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OQS03478.1 - 1.6e-16 60.5 0.0 9.1e-09 35.1 0.0 2.6 2 0 0 2 2 2 2 Protein kinase domain LRR_8 PF13855.6 OQS03478.1 - 0.11 12.3 4.6 0.21 11.4 1.5 2.6 2 1 1 3 3 3 0 Leucine rich repeat ATP12 PF07542.11 OQS03479.1 - 6e-34 116.9 0.4 2.7e-33 114.8 0.1 2.2 2 0 0 2 2 2 1 ATP12 chaperone protein Pkinase_Tyr PF07714.17 OQS03479.1 - 2.3e-18 66.5 0.0 6e-18 65.1 0.0 1.7 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OQS03479.1 - 1.2e-16 60.9 0.0 2.5e-16 59.9 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain LRR_8 PF13855.6 OQS03479.1 - 5.4e-05 22.9 0.6 0.00014 21.6 0.6 1.7 1 0 0 1 1 1 1 Leucine rich repeat LRR_4 PF12799.7 OQS03479.1 - 0.00018 21.8 3.2 0.00025 21.3 1.4 2.2 2 0 0 2 2 2 1 Leucine Rich repeats (2 copies) bZIP_1 PF00170.21 OQS03479.1 - 0.00025 21.1 4.2 0.00025 21.1 4.2 2.3 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.15 OQS03479.1 - 0.0026 17.8 3.8 0.0065 16.5 3.8 1.6 1 0 0 1 1 1 1 Basic region leucine zipper PAS_3 PF08447.12 OQS03479.1 - 0.0053 17.0 0.0 0.012 15.9 0.0 1.6 1 0 0 1 1 1 1 PAS fold PAS PF00989.25 OQS03479.1 - 0.038 14.0 0.0 0.086 12.8 0.0 1.6 1 0 0 1 1 1 0 PAS fold DUF2207 PF09972.9 OQS03479.1 - 0.072 11.8 0.0 0.12 11.2 0.0 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) RhoGEF67_u2 PF16614.5 OQS03479.1 - 0.1 12.7 0.0 0.26 11.4 0.0 1.6 1 0 0 1 1 1 0 Unstructured region two on RhoGEF 6 and 7 Orf78 PF06024.12 OQS03479.1 - 0.1 12.9 0.0 0.37 11.1 0.0 2.0 1 0 0 1 1 1 0 Orf78 (ac78) PAS_8 PF13188.7 OQS03479.1 - 0.12 12.4 0.0 0.36 10.9 0.0 1.9 1 0 0 1 1 1 0 PAS domain STT3 PF02516.14 OQS03480.1 - 3.8e-100 336.2 36.8 5.1e-97 325.8 32.1 2.1 2 0 0 2 2 2 2 Oligosaccharyl transferase STT3 subunit Rubis-subs-bind PF09273.11 OQS03480.1 - 1e-06 29.4 0.1 1.9e-06 28.6 0.1 1.5 1 0 0 1 1 1 1 Rubisco LSMT substrate-binding Phospholip_B PF04916.13 OQS03481.1 - 4.3e-155 517.3 2.9 5.7e-155 516.9 2.9 1.1 1 0 0 1 1 1 1 Phospholipase B Urease_alpha PF00449.20 OQS03481.1 - 4.5e-55 185.2 2.1 8.7e-55 184.2 2.1 1.5 1 0 0 1 1 1 1 Urease alpha-subunit, N-terminal domain Urease_gamma PF00547.18 OQS03481.1 - 2.8e-42 143.0 0.0 1.1e-41 141.1 0.0 2.2 2 0 0 2 2 2 1 Urease, gamma subunit Urease_beta PF00699.20 OQS03481.1 - 1.5e-35 121.1 0.0 3.5e-35 119.9 0.0 1.6 1 0 0 1 1 1 1 Urease beta subunit Amidohydro_1 PF01979.20 OQS03481.1 - 1.7e-32 113.1 4.4 2.7e-32 112.5 4.4 1.2 1 0 0 1 1 1 1 Amidohydrolase family WD40 PF00400.32 OQS03482.1 - 3.3e-33 113.2 31.5 0.00043 21.0 0.3 11.7 12 1 1 13 13 13 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OQS03482.1 - 2.8e-16 59.6 0.3 0.012 15.9 0.0 6.7 6 1 0 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 OQS03482.1 - 0.0015 17.9 0.0 2.7 7.3 0.0 3.8 2 2 0 4 4 4 2 WD40-like domain IL3Ra_N PF18611.1 OQS03482.1 - 0.026 14.5 0.1 0.073 13.1 0.1 1.7 1 0 0 1 1 1 0 IL-3 receptor alpha chain N-terminal domain Abhydrolase_4 PF08386.10 OQS03483.1 - 3.7e-05 23.8 0.0 8.5e-05 22.6 0.0 1.6 1 1 1 2 2 2 1 TAP-like protein Ank_4 PF13637.6 OQS03484.1 - 6.1e-14 52.2 4.1 2.2e-05 24.9 0.1 4.5 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank_2 PF12796.7 OQS03484.1 - 1.8e-12 47.7 2.5 2.1e-05 25.0 0.2 2.9 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OQS03484.1 - 1.8e-11 44.0 6.1 0.33 11.3 0.0 6.3 2 2 5 7 7 7 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQS03484.1 - 4e-08 32.9 0.7 2 9.2 0.0 6.1 5 2 1 6 6 6 2 Ankyrin repeat DUF5049 PF16468.5 OQS03484.1 - 0.0019 18.1 1.2 14 5.6 0.0 4.2 2 2 2 4 4 4 1 Domain of unknown function (DUF5049) Peptidase_C2 PF00648.21 OQS03485.1 - 2.3e-66 223.8 4.7 2.1e-65 220.7 4.5 2.1 1 1 0 1 1 1 1 Calpain family cysteine protease DnaJ-X PF14308.6 OQS03485.1 - 0.0042 16.6 2.2 0.0098 15.4 2.2 1.6 1 0 0 1 1 1 1 X-domain of DnaJ-containing DUF4746 PF15928.5 OQS03485.1 - 4.9 6.5 15.6 8.1 5.8 15.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) NOA36 PF06524.12 OQS03485.1 - 6.9 5.9 16.6 11 5.3 16.6 1.3 1 0 0 1 1 1 0 NOA36 protein RNA_pol_3_Rpc31 PF11705.8 OQS03485.1 - 9.7 6.4 21.4 15 5.8 21.4 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Cation_ATPase_N PF00690.26 OQS03486.1 - 0.14 11.9 0.0 0.15 11.8 0.0 1.1 1 0 0 1 1 1 0 Cation transporter/ATPase, N-terminus WD40 PF00400.32 OQS03487.1 - 5.3e-11 42.9 1.7 0.6 11.1 0.0 6.5 6 3 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OQS03487.1 - 8.9e-05 22.7 0.0 0.068 13.5 0.0 3.5 3 1 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 OQS03487.1 - 0.0085 16.0 0.0 0.022 14.6 0.0 1.7 1 1 0 1 1 1 1 Eukaryotic translation initiation factor eIF2A Lactonase PF10282.9 OQS03487.1 - 0.012 14.9 0.0 0.02 14.1 0.0 1.3 1 0 0 1 1 1 0 Lactonase, 7-bladed beta-propeller PD40 PF07676.12 OQS03487.1 - 0.021 14.8 0.0 0.33 10.9 0.0 2.4 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat Coatomer_WDAD PF04053.14 OQS03487.1 - 0.026 13.6 0.3 0.065 12.3 0.1 1.7 2 0 0 2 2 2 0 Coatomer WD associated region Arc_PepC PF06819.11 OQS03488.1 - 0.11 12.7 0.1 0.14 12.3 0.1 1.2 1 0 0 1 1 1 0 Archaeal Peptidase A24 C-terminal Domain Kelch_5 PF13854.6 OQS03488.1 - 0.13 12.3 0.0 0.26 11.3 0.0 1.4 1 0 0 1 1 1 0 Kelch motif THF_DHG_CYH_C PF02882.19 OQS03489.1 - 8.3e-66 220.2 0.5 8.3e-66 220.2 0.5 1.7 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.23 OQS03489.1 - 6.8e-40 136.0 0.1 1e-39 135.4 0.1 1.3 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain OCD_Mu_crystall PF02423.15 OQS03489.1 - 0.0011 18.0 0.4 0.0016 17.5 0.4 1.2 1 0 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family Gal_Lectin PF02140.18 OQS03490.1 - 8.3e-26 90.2 7.9 1.1e-12 48.2 0.6 3.9 3 1 0 3 3 3 3 Galactose binding lectin domain UPF0203 PF05254.12 OQS03491.1 - 3.2e-09 36.9 1.1 3.2e-09 36.9 1.1 4.1 5 0 0 5 5 5 1 Uncharacterised protein family (UPF0203) Elicitin PF00964.17 OQS03491.1 - 8.1e-07 29.1 1.4 8.1e-07 29.1 1.4 2.9 3 0 0 3 3 3 1 Elicitin DUF3800 PF12686.7 OQS03491.1 - 0.0096 16.5 0.0 5.7 7.6 0.0 3.7 1 1 0 1 1 1 1 Protein of unknown function (DUF3800) Abi_C PF14355.6 OQS03491.1 - 0.088 12.9 0.6 0.64 10.2 0.6 2.6 1 0 0 1 1 1 0 Abortive infection C-terminus Mvb12 PF09452.10 OQS03491.1 - 1.6 9.2 7.2 5.8 7.4 0.0 4.3 2 1 1 4 4 4 0 ESCRT-I subunit Mvb12 DsrC PF04358.13 OQS03491.1 - 4.4 7.9 7.9 55 4.3 0.0 4.0 3 1 0 3 3 3 0 DsrC like protein ZYG-11_interact PF05884.12 OQS03492.1 - 0.2 11.0 4.7 0.39 10.1 4.7 1.5 1 0 0 1 1 1 0 Interactor of ZYG-11 Mucin15 PF15672.5 OQS03492.1 - 0.93 8.9 13.4 1.2 8.5 13.4 1.1 1 0 0 1 1 1 0 Cell-membrane associated Mucin15 Ank_2 PF12796.7 OQS03493.1 - 5.5e-35 119.8 1.8 3.2e-10 40.4 0.0 4.9 2 2 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OQS03493.1 - 1.9e-24 83.1 4.5 0.00013 22.1 0.0 8.8 8 0 0 8 8 8 4 Ankyrin repeat Ank_4 PF13637.6 OQS03493.1 - 1.5e-23 82.8 5.9 7.3e-10 39.2 0.1 7.7 4 2 5 9 9 9 6 Ankyrin repeats (many copies) Ank PF00023.30 OQS03493.1 - 6.7e-23 80.1 3.9 0.002 18.5 0.0 7.9 7 0 0 7 7 7 5 Ankyrin repeat Ank_5 PF13857.6 OQS03493.1 - 6e-19 67.9 0.8 0.00013 22.2 0.0 6.0 3 2 3 6 6 6 5 Ankyrin repeats (many copies) BTB PF00651.31 OQS03493.1 - 6.2e-16 58.6 1.5 4.8e-08 33.2 0.1 3.8 2 1 0 2 2 2 2 BTB/POZ domain PAM2 PF07145.15 OQS03493.1 - 0.00088 18.8 0.2 0.0023 17.5 0.2 1.8 1 0 0 1 1 1 1 Ataxin-2 C-terminal region ROS_MUCR PF05443.11 OQS03494.1 - 4.2 7.4 8.6 0.59 10.2 0.8 2.9 2 1 1 3 3 3 0 ROS/MUCR transcriptional regulator protein Acetyltransf_CG PF14542.6 OQS03495.1 - 6.8e-19 67.8 0.0 8.6e-19 67.5 0.0 1.1 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_10 PF13673.7 OQS03495.1 - 1.8e-06 27.9 0.0 2e-06 27.8 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 OQS03495.1 - 1.1e-05 25.7 0.0 1.2e-05 25.5 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 OQS03495.1 - 0.0036 17.7 0.0 0.0043 17.5 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain GCN5L1 PF06320.13 OQS03496.1 - 0.024 14.8 0.1 0.053 13.7 0.1 1.5 1 0 0 1 1 1 0 GCN5-like protein 1 (GCN5L1) MCR_D PF02505.14 OQS03496.1 - 0.064 13.1 0.0 0.24 11.2 0.0 1.8 2 0 0 2 2 2 0 Methyl-coenzyme M reductase operon protein D PKD_channel PF08016.12 OQS03497.1 - 3.2e-19 68.9 14.5 1.6e-16 60.0 14.5 2.2 1 1 0 1 1 1 1 Polycystin cation channel Apq12 PF12716.7 OQS03499.1 - 0.14 12.1 2.7 0.38 10.7 2.7 1.7 1 0 0 1 1 1 0 Nuclear pore assembly and biogenesis DUF1324 PF07038.11 OQS03500.1 - 1.2 9.4 4.0 0.61 10.4 0.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1324) MFS_2 PF13347.6 OQS03501.1 - 1.9e-11 43.2 8.4 1.9e-11 43.2 8.4 3.0 2 1 1 3 3 3 2 MFS/sugar transport protein Pkinase_Tyr PF07714.17 OQS03502.1 - 6.8e-22 78.0 0.0 1.3e-21 77.0 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OQS03502.1 - 1e-20 74.2 0.0 1.8e-20 73.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain LRR_8 PF13855.6 OQS03502.1 - 0.00062 19.5 0.1 0.016 14.9 0.2 2.9 2 0 0 2 2 2 1 Leucine rich repeat DUF1180 PF06679.12 OQS03502.1 - 0.0097 16.3 0.4 0.017 15.6 0.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1180) LRR_4 PF12799.7 OQS03502.1 - 0.47 11.0 2.9 2.2 8.8 0.1 3.1 2 1 0 2 2 2 0 Leucine Rich repeats (2 copies) SNF2_N PF00176.23 OQS03503.1 - 3.4e-62 210.2 0.3 3.4e-62 210.2 0.3 2.5 2 0 0 2 2 2 1 SNF2 family N-terminal domain Chromo PF00385.24 OQS03503.1 - 1.1e-21 76.4 3.5 1.8e-10 40.6 0.5 3.0 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain Helicase_C PF00271.31 OQS03503.1 - 1.4e-19 70.4 0.1 9.5e-19 67.8 0.0 2.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 OQS03503.1 - 2.5e-10 40.6 0.0 2.5e-10 40.6 0.0 4.6 6 1 0 6 6 6 1 Type III restriction enzyme, res subunit PHD PF00628.29 OQS03503.1 - 1.4e-06 28.1 4.9 1.4e-06 28.1 4.9 3.6 3 0 0 3 3 3 1 PHD-finger DEAD PF00270.29 OQS03503.1 - 2.2e-05 24.3 0.1 0.00012 21.9 0.0 2.5 2 0 0 2 2 2 1 DEAD/DEAH box helicase zf-RanBP PF00641.18 OQS03503.1 - 2.9e-05 23.3 6.2 2.9e-05 23.3 6.2 2.0 2 0 0 2 2 2 1 Zn-finger in Ran binding protein and others Cys_rich_CPCC PF14206.6 OQS03503.1 - 0.013 15.3 0.1 0.063 13.1 0.1 2.3 1 0 0 1 1 1 0 Cysteine-rich CPCC Patched PF02460.18 OQS03503.1 - 0.093 10.8 2.6 0.25 9.4 2.6 1.7 1 0 0 1 1 1 0 Patched family zinc_ribbon_2 PF13240.6 OQS03503.1 - 0.11 12.3 3.9 0.39 10.5 3.9 2.0 1 0 0 1 1 1 0 zinc-ribbon domain TMEM154 PF15102.6 OQS03504.1 - 0.037 13.9 0.0 0.063 13.2 0.0 1.4 1 0 0 1 1 1 0 TMEM154 protein family Glyco_hydro_18 PF00704.28 OQS03505.1 - 3.6e-19 69.6 1.0 9.4e-19 68.3 0.3 1.9 1 1 0 2 2 2 1 Glycosyl hydrolases family 18 HAUS-augmin3 PF14932.6 OQS03505.1 - 0.0064 16.1 8.8 0.011 15.4 8.8 1.3 1 0 0 1 1 1 1 HAUS augmin-like complex subunit 3 DUF848 PF05852.11 OQS03505.1 - 0.14 12.3 7.3 0.33 11.1 7.3 1.6 1 0 0 1 1 1 0 Gammaherpesvirus protein of unknown function (DUF848) zf-C4H2 PF10146.9 OQS03505.1 - 0.55 10.5 12.2 1.1 9.5 12.2 1.5 1 0 0 1 1 1 0 Zinc finger-containing protein Syntaxin_2 PF14523.6 OQS03505.1 - 0.78 10.2 16.9 0.71 10.3 6.3 2.6 1 1 1 2 2 2 0 Syntaxin-like protein DUF745 PF05335.13 OQS03505.1 - 4.2 7.1 14.8 2 8.1 9.0 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF745) Phage_Mu_Gam PF07352.12 OQS03505.1 - 6.9 6.6 9.1 68 3.3 9.0 2.3 1 1 0 1 1 1 0 Bacteriophage Mu Gam like protein CDC50 PF03381.15 OQS03506.1 - 9.2e-53 179.6 0.0 1.2e-52 179.1 0.0 1.2 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family DUF2721 PF11026.8 OQS03506.1 - 4.8 7.1 5.2 8 6.4 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2721) Mrr_cat PF04471.12 OQS03507.1 - 0.017 15.1 0.0 0.034 14.2 0.0 1.5 1 0 0 1 1 1 0 Restriction endonuclease HEAT PF02985.22 OQS03508.1 - 1.9e-16 58.8 6.3 0.2 12.0 0.0 7.0 6 0 0 6 6 6 6 HEAT repeat HEAT_2 PF13646.6 OQS03508.1 - 4.7e-13 49.3 1.3 0.00019 21.7 0.0 4.7 2 1 2 4 4 4 3 HEAT repeats PDZ_6 PF17820.1 OQS03508.1 - 1.6e-10 40.7 0.2 7.2e-05 22.6 0.0 2.9 3 0 0 3 3 3 2 PDZ domain PDZ_2 PF13180.6 OQS03508.1 - 3.7e-09 36.8 0.2 0.00083 19.6 0.0 2.5 2 0 0 2 2 2 2 PDZ domain UBA_4 PF14555.6 OQS03508.1 - 1.1e-07 31.5 0.8 0.0029 17.4 0.1 3.4 3 0 0 3 3 3 2 UBA-like domain Cnd1 PF12717.7 OQS03508.1 - 5.4e-07 29.8 2.0 0.23 11.5 0.0 4.5 3 1 1 4 4 4 2 non-SMC mitotic condensation complex subunit 1 PDZ PF00595.24 OQS03508.1 - 7.2e-07 29.5 0.1 0.034 14.5 0.0 2.5 2 0 0 2 2 2 2 PDZ domain HEAT_EZ PF13513.6 OQS03508.1 - 0.0012 19.3 5.1 17 6.1 0.0 5.2 4 1 2 6 6 6 0 HEAT-like repeat DUF1296 PF06972.11 OQS03508.1 - 0.0015 18.7 0.1 0.1 12.7 0.1 3.1 3 0 0 3 3 3 1 Protein of unknown function (DUF1296) CUE PF02845.16 OQS03508.1 - 0.038 13.7 1.2 0.17 11.6 0.1 2.6 3 0 0 3 3 3 0 CUE domain Adaptin_N PF01602.20 OQS03508.1 - 0.041 12.4 0.2 0.19 10.2 0.1 2.2 2 1 0 2 2 2 0 Adaptin N terminal region HBS1_N PF08938.10 OQS03508.1 - 0.36 11.1 1.6 0.93 9.8 1.6 1.7 1 0 0 1 1 1 0 HBS1 N-terminus Herpes_BLRF2 PF05812.12 OQS03509.1 - 4.4 7.5 12.9 7.8 6.7 7.2 3.0 1 1 1 2 2 2 0 Herpesvirus BLRF2 protein PK PF00224.21 OQS03510.1 - 3e-145 483.5 1.0 3.6e-145 483.2 0.3 1.5 2 0 0 2 2 2 1 Pyruvate kinase, barrel domain PK_C PF02887.16 OQS03510.1 - 8.7e-30 103.4 0.3 1.9e-29 102.2 0.3 1.6 1 0 0 1 1 1 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.14 OQS03510.1 - 0.0015 17.8 0.4 0.0046 16.1 0.2 1.7 1 1 0 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family AIDA PF16168.5 OQS03510.1 - 0.18 11.9 0.8 0.49 10.5 0.8 1.7 1 0 0 1 1 1 0 Adhesin of bacterial autotransporter system, probable stalk PDEase_I PF00233.19 OQS03511.1 - 7.5e-62 209.1 3.9 1.4e-61 208.2 3.9 1.4 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase Guanylate_cyc PF00211.20 OQS03511.1 - 9.9e-10 38.3 0.0 2.2e-09 37.2 0.0 1.5 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain DHDPS PF00701.22 OQS03512.1 - 3.2e-90 301.8 0.3 3.6e-90 301.6 0.3 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family PA PF02225.22 OQS03512.1 - 0.054 13.5 1.1 0.13 12.3 0.1 2.0 2 1 0 2 2 2 0 PA domain SRF-TF PF00319.18 OQS03512.1 - 0.23 11.0 0.6 24 4.5 0.1 2.5 2 0 0 2 2 2 0 SRF-type transcription factor (DNA-binding and dimerisation domain) Rieske_2 PF13806.6 OQS03513.1 - 3.4e-11 43.0 0.0 4.5e-11 42.6 0.0 1.2 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain Rieske PF00355.26 OQS03513.1 - 8.4e-11 41.7 0.0 1.3e-10 41.1 0.0 1.2 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Phage_attach PF05354.11 OQS03514.1 - 0.14 12.1 0.0 0.33 10.8 0.0 1.6 1 0 0 1 1 1 0 Phage Head-Tail Attachment Pkinase PF00069.25 OQS03515.1 - 3.1e-10 39.9 0.0 3.9e-10 39.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pox_ser-thr_kin PF05445.11 OQS03515.1 - 0.051 12.5 0.0 0.074 12.0 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Myotub-related PF06602.14 OQS03516.1 - 1.6e-58 198.3 0.0 2.2e-58 197.9 0.0 1.2 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain GRAM PF02893.20 OQS03516.1 - 0.0024 17.7 0.1 0.0066 16.3 0.1 1.7 1 0 0 1 1 1 1 GRAM domain DUF3591 PF12157.8 OQS03517.1 - 1.7e-99 333.5 0.0 1.7e-99 333.5 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF3591) HELP PF03451.14 OQS03517.1 - 1.6e-59 197.6 1.4 9.7e-19 67.0 0.0 3.6 3 0 0 3 3 3 3 HELP motif WD40 PF00400.32 OQS03517.1 - 9e-43 143.4 76.1 0.00092 20.0 0.1 21.8 23 0 0 23 23 23 11 WD domain, G-beta repeat Bromodomain PF00439.25 OQS03517.1 - 4e-17 62.0 0.5 1.1e-15 57.4 0.0 3.1 3 0 0 3 3 3 1 Bromodomain ANAPC4_WD40 PF12894.7 OQS03517.1 - 6.4e-15 55.2 3.5 0.027 14.7 0.0 9.5 8 2 1 9 9 9 3 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 OQS03517.1 - 0.0093 15.3 0.2 3.9 6.7 0.0 3.6 3 0 0 3 3 3 1 WD40-like domain zf-CCHC_6 PF15288.6 OQS03517.1 - 0.013 15.3 0.5 0.032 14.1 0.5 1.7 1 0 0 1 1 1 0 Zinc knuckle Cytochrom_D1 PF02239.16 OQS03517.1 - 0.065 11.7 0.0 0.7 8.4 0.0 2.5 2 0 0 2 2 2 0 Cytochrome D1 heme domain PD40 PF07676.12 OQS03517.1 - 0.081 12.9 0.0 17 5.5 0.0 3.2 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat Peptidase_C2 PF00648.21 OQS03518.1 - 5e-63 212.9 1.0 1.6e-59 201.4 0.0 3.0 3 0 0 3 3 3 2 Calpain family cysteine protease EF-hand_1 PF00036.32 OQS03518.1 - 8.6e-16 56.2 4.6 0.00062 19.1 0.3 4.9 4 0 0 4 4 4 3 EF hand EF-hand_7 PF13499.6 OQS03518.1 - 1.3e-14 54.4 2.3 2.2e-09 37.6 0.1 5.1 5 0 0 5 5 5 2 EF-hand domain pair EF-hand_8 PF13833.6 OQS03518.1 - 2.7e-12 46.4 5.2 2.9e-06 27.0 0.1 5.1 4 1 1 5 5 5 3 EF-hand domain pair EF-hand_6 PF13405.6 OQS03518.1 - 2.3e-10 39.5 6.6 0.01 15.7 0.6 4.8 4 0 0 4 4 4 3 EF-hand domain Calpain_III PF01067.22 OQS03518.1 - 2.6e-09 37.5 0.0 6e-08 33.1 0.0 2.7 1 1 0 1 1 1 1 Calpain large subunit, domain III EF-hand_5 PF13202.6 OQS03518.1 - 2.3e-08 33.2 6.7 0.026 14.0 0.1 3.7 3 0 0 3 3 3 3 EF hand EF-hand_9 PF14658.6 OQS03518.1 - 0.0075 16.6 0.5 4.1 7.8 0.0 3.8 4 0 0 4 4 4 1 EF-hand domain Pox_A_type_inc PF04508.12 OQS03518.1 - 0.087 12.7 0.1 0.28 11.1 0.1 2.0 1 0 0 1 1 1 0 Viral A-type inclusion protein repeat DZR PF12773.7 OQS03518.1 - 0.46 10.5 6.5 1.6 8.8 6.5 1.9 1 0 0 1 1 1 0 Double zinc ribbon EspF PF04806.12 OQS03518.1 - 0.48 10.9 4.3 1.3 9.5 4.3 1.7 1 0 0 1 1 1 0 EspF protein repeat zinc_ribbon_2 PF13240.6 OQS03518.1 - 0.48 10.2 7.6 1.2 8.9 7.6 1.7 1 0 0 1 1 1 0 zinc-ribbon domain CEBP_ZZ PF16366.5 OQS03518.1 - 3.6 7.9 5.5 12 6.2 5.5 1.9 1 0 0 1 1 1 0 Cytoplasmic polyadenylation element-binding protein ZZ domain zf-RING_5 PF14634.6 OQS03518.1 - 6 6.9 14.6 3.1 7.8 0.5 2.8 2 0 0 2 2 2 0 zinc-RING finger domain Occludin_ELL PF07303.13 OQS03518.1 - 7.5 7.3 7.2 5.9 7.7 3.8 2.7 2 0 0 2 2 1 0 Occludin homology domain CH_2 PF06294.11 OQS03519.1 - 1.9e-33 114.5 2.1 2.4e-33 114.1 0.1 2.4 3 0 0 3 3 3 1 CH-like domain in sperm protein CAMSAP_CH PF11971.8 OQS03519.1 - 3.6e-17 62.0 0.0 8.2e-17 60.8 0.0 1.7 1 0 0 1 1 1 1 CAMSAP CH domain MPS2 PF17060.5 OQS03519.1 - 0.029 13.7 0.3 0.063 12.5 0.3 1.5 1 0 0 1 1 1 0 Monopolar spindle protein 2 CH PF00307.31 OQS03519.1 - 0.042 14.0 0.5 0.097 12.9 0.1 1.8 2 0 0 2 2 1 0 Calponin homology (CH) domain Spc29 PF17082.5 OQS03519.1 - 0.15 11.9 3.0 0.26 11.1 3.0 1.4 1 0 0 1 1 1 0 Spindle Pole Component 29 Spc7 PF08317.11 OQS03519.1 - 0.18 10.7 2.2 0.31 9.9 2.2 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF641 PF04859.12 OQS03519.1 - 0.2 12.0 2.2 0.6 10.4 2.2 1.8 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) BLOC1_2 PF10046.9 OQS03519.1 - 0.26 11.6 4.0 0.75 10.1 4.0 1.8 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF3713 PF12506.8 OQS03519.1 - 0.38 11.1 3.5 0.76 10.1 0.5 3.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3713) FAM76 PF16046.5 OQS03519.1 - 0.38 10.0 1.4 0.57 9.5 1.4 1.1 1 0 0 1 1 1 0 FAM76 protein DUF16 PF01519.16 OQS03519.1 - 0.68 10.4 5.7 0.18 12.3 1.2 2.2 2 0 0 2 2 2 0 Protein of unknown function DUF16 DUF4404 PF14357.6 OQS03519.1 - 0.84 10.3 3.8 2.7 8.7 3.8 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4404) PKcGMP_CC PF16808.5 OQS03519.1 - 1.1 9.1 5.9 8.1 6.4 0.2 2.6 2 0 0 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase MatE PF01554.18 OQS03521.1 - 1.1e-25 90.2 25.9 1.6e-16 60.4 4.2 2.6 2 1 0 2 2 2 2 MatE Pilin_N PF07790.11 OQS03521.1 - 0.13 13.2 0.1 0.36 11.8 0.1 1.7 1 0 0 1 1 1 0 Archaeal Type IV pilin, N-terminal DUF1129 PF06570.11 OQS03521.1 - 0.71 9.3 9.8 0.94 8.9 0.2 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF1129) Pkinase PF00069.25 OQS03522.1 - 4e-33 114.9 0.1 2.4e-25 89.4 0.0 2.4 2 0 0 2 2 2 2 Protein kinase domain Kinase-like PF14531.6 OQS03522.1 - 2.2e-06 27.2 0.0 6e-06 25.8 0.0 1.7 2 0 0 2 2 2 1 Kinase-like Pkinase_Tyr PF07714.17 OQS03522.1 - 2.4e-05 23.7 0.2 0.0037 16.6 0.0 2.7 2 1 0 2 2 2 2 Protein tyrosine kinase APH PF01636.23 OQS03522.1 - 0.0037 17.2 0.0 0.0074 16.2 0.0 1.5 2 0 0 2 2 2 1 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.11 OQS03522.1 - 0.054 12.5 0.1 0.11 11.5 0.1 1.4 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Flavodoxin_2 PF02525.17 OQS03523.1 - 4.9e-24 85.1 0.0 6.1e-24 84.8 0.0 1.0 1 0 0 1 1 1 1 Flavodoxin-like fold FMN_red PF03358.15 OQS03523.1 - 5.7e-12 45.6 0.0 7.8e-12 45.2 0.0 1.2 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Pkinase PF00069.25 OQS03524.1 - 1e-55 189.0 0.1 2.4e-52 177.9 0.0 2.0 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OQS03524.1 - 4.9e-32 111.2 0.0 6.1e-32 110.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OQS03524.1 - 6e-07 29.1 0.0 1.4e-05 24.6 0.0 2.1 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 OQS03524.1 - 0.00014 21.3 0.1 0.00019 20.8 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OQS03524.1 - 0.00016 21.7 0.1 0.096 12.6 0.0 2.1 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 OQS03524.1 - 0.0081 15.0 0.0 0.012 14.4 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 OQS03524.1 - 0.18 10.7 0.0 0.26 10.2 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain MatE PF01554.18 OQS03525.1 - 3.4e-16 59.3 13.1 3.4e-16 59.3 13.1 1.5 1 1 1 2 2 2 1 MatE Kinesin PF00225.23 OQS03526.1 - 1e-110 369.8 1.3 2.6e-110 368.5 1.3 1.7 1 1 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 OQS03526.1 - 3.9e-28 98.3 0.0 1.5e-27 96.3 0.0 2.1 1 0 0 1 1 1 1 Microtubule binding Spc7 PF08317.11 OQS03526.1 - 0.00026 20.0 2.8 0.00026 20.0 2.8 3.3 3 0 0 3 3 3 2 Spc7 kinetochore protein PIF1 PF05970.14 OQS03526.1 - 0.044 12.9 2.0 0.15 11.2 0.2 2.5 2 0 0 2 2 2 0 PIF1-like helicase DUF641 PF04859.12 OQS03526.1 - 1.4 9.3 29.5 0.27 11.6 4.8 4.1 3 1 1 4 4 4 0 Plant protein of unknown function (DUF641) NPV_P10 PF05531.12 OQS03526.1 - 1.7 9.2 9.6 0.15 12.5 1.5 3.5 3 2 2 5 5 5 0 Nucleopolyhedrovirus P10 protein DUF3209 PF11483.8 OQS03526.1 - 2.3 8.7 14.3 0.042 14.3 4.0 3.3 3 1 2 5 5 5 0 Protein of unknown function (DUF3209) AAA_2 PF07724.14 OQS03527.1 - 6e-45 153.4 1.0 8.2e-37 126.9 0.8 2.7 2 1 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA PF00004.29 OQS03527.1 - 3.1e-17 63.2 0.6 1.9e-07 31.6 0.1 2.9 1 1 2 3 3 3 2 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.9 OQS03527.1 - 2.9e-08 33.6 3.0 8.7e-08 32.1 0.2 2.8 2 0 0 2 2 2 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.14 OQS03527.1 - 3.2e-08 33.7 0.3 1.5e-05 25.0 0.0 2.6 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 OQS03527.1 - 2.4e-07 30.6 0.4 5.7e-05 22.9 0.1 3.4 3 0 0 3 3 3 1 Holliday junction DNA helicase RuvB P-loop domain MCM PF00493.23 OQS03527.1 - 3.7e-06 26.2 0.1 0.0018 17.4 0.0 2.7 3 0 0 3 3 2 1 MCM P-loop domain AAA_22 PF13401.6 OQS03527.1 - 8.6e-06 26.1 0.2 0.00018 21.8 0.0 2.4 1 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 OQS03527.1 - 1.5e-05 25.5 1.4 6.9e-05 23.3 0.1 2.6 2 1 0 2 2 2 1 AAA ATPase domain ATP-synt_ab PF00006.25 OQS03527.1 - 1.5e-05 24.7 0.3 0.00011 21.9 0.3 2.0 1 1 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain Mg_chelatase PF01078.21 OQS03527.1 - 3.6e-05 23.3 0.3 0.0016 17.8 0.0 3.1 3 1 0 3 3 3 1 Magnesium chelatase, subunit ChlI G-alpha PF00503.20 OQS03527.1 - 7.7e-05 22.0 0.0 0.0001 21.6 0.0 1.2 1 0 0 1 1 1 1 G-protein alpha subunit AAA_33 PF13671.6 OQS03527.1 - 0.00046 20.4 0.2 0.0012 19.0 0.0 1.8 2 0 0 2 2 1 1 AAA domain Sigma54_activat PF00158.26 OQS03527.1 - 0.00089 19.0 0.0 0.045 13.5 0.0 2.7 2 0 0 2 2 2 1 Sigma-54 interaction domain Zeta_toxin PF06414.12 OQS03527.1 - 0.0011 18.3 0.1 0.0034 16.7 0.0 1.9 2 0 0 2 2 2 1 Zeta toxin AAA_18 PF13238.6 OQS03527.1 - 0.0011 19.5 0.3 0.0093 16.5 0.0 2.5 3 0 0 3 3 2 1 AAA domain AAA_14 PF13173.6 OQS03527.1 - 0.0037 17.3 0.1 2.7 8.0 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.6 OQS03527.1 - 0.0064 16.7 0.2 0.041 14.1 0.0 2.4 3 1 0 3 3 2 1 AAA domain ABC_tran PF00005.27 OQS03527.1 - 0.0083 16.6 0.1 0.02 15.4 0.1 1.7 1 1 0 1 1 1 1 ABC transporter PduV-EutP PF10662.9 OQS03527.1 - 0.01 15.6 0.1 0.054 13.2 0.0 2.2 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation TniB PF05621.11 OQS03527.1 - 0.017 14.6 0.1 0.059 12.8 0.0 2.0 2 1 0 2 2 1 0 Bacterial TniB protein IstB_IS21 PF01695.17 OQS03527.1 - 0.019 14.7 0.4 0.094 12.4 0.4 2.1 1 1 0 1 1 1 0 IstB-like ATP binding protein Rad17 PF03215.15 OQS03527.1 - 0.025 14.5 0.2 0.068 13.1 0.0 1.9 1 1 1 2 2 2 0 Rad17 P-loop domain ATPase_2 PF01637.18 OQS03527.1 - 0.029 14.3 3.4 1.8 8.4 3.0 2.7 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea RsgA_GTPase PF03193.16 OQS03527.1 - 0.038 13.9 0.2 0.91 9.4 0.0 2.6 2 1 1 3 3 3 0 RsgA GTPase AAA_7 PF12775.7 OQS03527.1 - 0.043 13.3 0.0 0.11 12.0 0.0 1.7 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_19 PF13245.6 OQS03527.1 - 0.072 13.4 6.1 0.048 14.0 3.0 2.3 2 1 0 2 2 1 0 AAA domain NACHT PF05729.12 OQS03527.1 - 0.079 12.9 0.0 0.6 10.0 0.0 2.5 2 1 0 2 2 2 0 NACHT domain AAA_24 PF13479.6 OQS03527.1 - 0.093 12.4 0.3 0.33 10.7 0.1 2.0 1 1 1 2 2 2 0 AAA domain TsaE PF02367.17 OQS03527.1 - 0.095 12.7 0.0 0.26 11.3 0.0 1.7 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE RNA_helicase PF00910.22 OQS03527.1 - 0.1 13.0 0.0 0.49 10.8 0.0 2.2 2 0 0 2 2 2 0 RNA helicase SRP54 PF00448.22 OQS03527.1 - 0.13 11.8 2.9 0.25 10.9 0.0 2.8 3 1 0 3 3 3 0 SRP54-type protein, GTPase domain NTPase_1 PF03266.15 OQS03527.1 - 0.41 10.5 4.4 1.3 8.9 0.2 3.0 1 1 0 2 2 2 0 NTPase AAA_17 PF13207.6 OQS03527.1 - 3.7 8.0 7.3 8 6.9 0.2 3.5 4 1 0 4 4 3 0 AAA domain Ank_4 PF13637.6 OQS03528.1 - 0.017 15.7 0.0 0.11 13.1 0.1 2.2 2 1 0 2 2 2 0 Ankyrin repeats (many copies) DAGAT PF03982.13 OQS03529.1 - 0.00056 18.9 0.0 0.00064 18.7 0.0 1.2 1 0 0 1 1 1 1 Diacylglycerol acyltransferase MatE PF01554.18 OQS03530.1 - 5.6e-167 549.5 161.7 2.1e-24 86.0 9.6 8.7 9 0 0 9 9 9 8 MatE Nas2_N PF18265.1 OQS03530.1 - 1.8e-24 85.5 0.0 3.6e-24 84.5 0.0 1.6 1 0 0 1 1 1 1 Nas2 N_terminal domain Polysacc_synt_C PF14667.6 OQS03530.1 - 0.004 17.2 13.9 0.004 17.2 13.9 12.9 10 5 5 15 15 15 8 Polysaccharide biosynthesis C-terminal domain PDZ_6 PF17820.1 OQS03530.1 - 0.011 15.6 0.0 0.021 14.7 0.0 1.5 1 0 0 1 1 1 0 PDZ domain PDZ PF00595.24 OQS03530.1 - 0.028 14.7 0.0 0.065 13.6 0.0 1.6 1 0 0 1 1 1 0 PDZ domain MatE PF01554.18 OQS03531.1 - 8.5e-49 165.3 33.5 4.6e-25 88.1 8.8 2.5 2 0 0 2 2 2 2 MatE STIMATE PF12400.8 OQS03532.1 - 3.2e-32 111.7 8.6 3.2e-32 111.7 8.6 1.5 2 0 0 2 2 2 1 STIMATE family Aldedh PF00171.22 OQS03533.1 - 2.3e-66 224.2 0.0 2.6e-66 224.0 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Sugar_tr PF00083.24 OQS03534.1 - 1.6e-92 310.7 22.2 2.2e-92 310.3 22.2 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OQS03534.1 - 1.3e-29 103.3 34.8 4.2e-19 68.7 11.0 2.1 1 1 0 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 OQS03534.1 - 5.9e-07 28.3 3.4 5.9e-07 28.3 3.4 2.2 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Ank_2 PF12796.7 OQS03535.1 - 3e-104 341.8 26.8 9.8e-16 58.1 0.0 8.4 3 1 6 9 9 9 9 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OQS03535.1 - 6.7e-80 253.4 11.0 6e-05 23.1 0.0 16.5 16 1 1 17 17 17 13 Ankyrin repeat Ank PF00023.30 OQS03535.1 - 5.2e-75 244.9 23.8 3.1e-06 27.4 0.1 16.5 16 1 0 16 16 16 14 Ankyrin repeat Ank_5 PF13857.6 OQS03535.1 - 1.5e-69 229.1 26.6 6.9e-09 35.8 0.1 13.1 5 2 6 12 12 12 12 Ankyrin repeats (many copies) Ank_4 PF13637.6 OQS03535.1 - 4e-68 225.0 13.0 5.7e-09 36.3 0.0 13.3 1 1 16 17 17 17 15 Ankyrin repeats (many copies) ATPase PF06745.13 OQS03535.1 - 0.0005 19.5 0.2 2.7 7.3 0.0 3.7 3 1 1 4 4 4 2 KaiC DUF1593 PF07632.11 OQS03535.1 - 0.057 12.9 2.6 3.2 7.1 0.0 3.8 4 1 1 5 5 5 0 Protein of unknown function (DUF1593) Arg_repressor PF01316.21 OQS03535.1 - 1.1 9.1 3.5 1.3e+02 2.4 0.0 5.2 8 0 0 8 8 8 0 Arginine repressor, DNA binding domain TFIIIC_sub6 PF10419.9 OQS03536.1 - 1.2e-09 37.9 0.0 1.6e-09 37.5 0.0 1.1 1 0 0 1 1 1 1 TFIIIC subunit triple barrel domain Bax1-I PF01027.20 OQS03537.1 - 3.4e-32 112.0 28.5 4.1e-32 111.7 28.5 1.1 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 EbsA PF17255.2 OQS03537.1 - 0.45 10.9 7.2 0.14 12.5 3.0 2.1 1 1 1 2 2 2 0 EbsA-like protein Deltameth_res PF16020.5 OQS03537.1 - 1.7 8.6 5.8 7.8 6.5 0.3 3.1 1 1 2 3 3 3 0 Deltamethrin resistance Pkinase PF00069.25 OQS03538.1 - 8.5e-89 297.4 0.0 1.5e-46 158.9 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OQS03538.1 - 4.8e-82 275.1 0.0 4.6e-44 150.6 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Ricin_B_lectin PF00652.22 OQS03538.1 - 1.2e-18 67.5 14.5 3.3e-06 27.4 0.5 5.3 3 2 3 6 6 6 5 Ricin-type beta-trefoil lectin domain TIR_2 PF13676.6 OQS03538.1 - 2.6e-14 53.8 0.0 1.4e-12 48.2 0.0 2.8 2 0 0 2 2 2 1 TIR domain Ank_5 PF13857.6 OQS03538.1 - 3.9e-10 39.8 0.3 0.00094 19.4 0.1 2.8 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 OQS03538.1 - 6.4e-09 36.3 0.0 0.001 19.6 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Pkinase_fungal PF17667.1 OQS03538.1 - 8.3e-09 34.7 0.2 0.0027 16.6 0.1 2.4 2 0 0 2 2 2 2 Fungal protein kinase Ank_4 PF13637.6 OQS03538.1 - 6e-07 29.9 0.7 0.021 15.4 0.1 2.7 2 0 0 2 2 2 2 Ankyrin repeats (many copies) SAM_1 PF00536.30 OQS03538.1 - 5e-06 26.9 0.0 1.3e-05 25.5 0.0 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Ank_3 PF13606.6 OQS03538.1 - 5.9e-06 26.2 0.9 0.4 11.4 0.1 4.5 4 0 0 4 4 4 2 Ankyrin repeat Kinase-like PF14531.6 OQS03538.1 - 6e-05 22.5 0.0 0.053 12.8 0.0 2.3 2 0 0 2 2 2 2 Kinase-like APH PF01636.23 OQS03538.1 - 0.00016 21.7 0.6 0.49 10.3 0.1 2.2 2 0 0 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 OQS03538.1 - 0.00054 19.4 0.9 0.15 11.4 0.1 2.4 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family SAM_2 PF07647.17 OQS03538.1 - 0.002 18.2 0.0 0.005 16.9 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Haspin_kinase PF12330.8 OQS03538.1 - 0.01 14.8 0.1 2.3 7.1 0.0 2.3 2 0 0 2 2 2 0 Haspin like kinase domain EAGR_box PF16713.5 OQS03538.1 - 0.013 15.1 11.6 1.8 8.3 0.9 5.7 6 0 0 6 6 6 0 Enriched in aromatic and glycine Residues box Ank PF00023.30 OQS03538.1 - 0.017 15.5 5.2 0.17 12.4 0.4 4.1 3 1 1 4 4 4 0 Ankyrin repeat Ricin_B_lectin PF00652.22 OQS03539.1 - 5.7e-10 39.5 2.2 1.8e-09 37.9 1.2 2.1 2 0 0 2 2 2 1 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.6 OQS03539.1 - 0.0027 18.4 1.5 0.011 16.4 0.6 2.3 2 0 0 2 2 2 1 Ricin-type beta-trefoil lectin domain-like CDtoxinA PF03498.14 OQS03539.1 - 0.0058 16.2 1.0 0.08 12.5 0.4 2.3 2 0 0 2 2 2 1 Cytolethal distending toxin A/C domain Bee_toxin PF17454.2 OQS03539.1 - 0.055 13.5 1.6 6.6 6.9 0.1 3.0 3 0 0 3 3 3 0 Honey bee toxin Ricin_B_lectin PF00652.22 OQS03540.1 - 3.3e-32 111.4 27.8 6.5e-13 49.0 6.0 5.0 4 1 0 4 4 4 4 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.6 OQS03540.1 - 1.9e-13 50.9 21.0 0.00098 19.8 1.2 6.2 4 2 2 6 6 6 6 Ricin-type beta-trefoil lectin domain-like CDtoxinA PF03498.14 OQS03540.1 - 6.5e-09 35.5 16.1 1.4e-05 24.8 0.7 4.9 4 1 0 4 4 4 4 Cytolethal distending toxin A/C domain S-layer PF07752.11 OQS03540.1 - 0.35 9.9 2.4 0.62 9.1 0.7 2.1 2 0 0 2 2 2 0 S-layer protein Ank_4 PF13637.6 OQS03542.1 - 5.5e-17 61.9 10.5 0.0024 18.4 0.1 6.4 5 1 1 6 6 6 5 Ankyrin repeats (many copies) Ank_2 PF12796.7 OQS03542.1 - 7e-17 61.8 11.1 4.1e-07 30.5 0.9 4.7 2 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OQS03542.1 - 2.4e-12 46.8 9.0 0.011 16.1 0.0 7.8 2 2 6 9 9 9 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQS03542.1 - 2.3e-10 39.8 9.2 28 5.7 0.1 9.4 8 2 1 9 9 9 1 Ankyrin repeat DUF5049 PF16468.5 OQS03542.1 - 0.0019 18.1 4.0 2.6 8.0 0.0 5.8 4 1 4 8 8 8 1 Domain of unknown function (DUF5049) Ank PF00023.30 OQS03542.1 - 0.0024 18.2 3.3 56 4.4 0.0 6.1 5 2 1 6 6 6 0 Ankyrin repeat DUF3792 PF12670.7 OQS03543.1 - 0.0011 19.1 0.3 0.0012 19.0 0.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3792) FAM165 PF14981.6 OQS03543.1 - 0.19 11.5 0.0 0.3 10.9 0.0 1.3 1 0 0 1 1 1 0 FAM165 family Glyco_transf_24 PF18404.1 OQS03544.1 - 2.7e-137 456.5 3.8 4.5e-137 455.8 3.8 1.3 1 0 0 1 1 1 1 Glucosyltransferase 24 Glyco_hydro_19 PF00182.19 OQS03544.1 - 6.5e-43 147.3 3.5 7.6e-42 143.8 3.5 2.6 1 1 0 1 1 1 1 Chitinase class I Thioredoxin_14 PF18402.1 OQS03544.1 - 3.4e-25 89.5 0.2 1.1e-24 87.8 0.1 1.9 2 0 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_12 PF18400.1 OQS03544.1 - 4.9e-25 88.5 0.0 7.1e-24 84.7 0.0 2.3 2 0 0 2 2 2 1 Thioredoxin-like domain UDP-g_GGTase PF06427.11 OQS03544.1 - 8e-24 83.9 0.0 1.9e-23 82.7 0.0 1.6 1 0 0 1 1 1 1 UDP-glucose:Glycoprotein Glucosyltransferase LPMO_10 PF03067.15 OQS03544.1 - 1.4e-21 78.0 0.1 3.7e-21 76.7 0.1 1.8 1 0 0 1 1 1 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading Thioredoxin_13 PF18401.1 OQS03544.1 - 4.4e-16 59.0 2.0 8.9e-16 58.0 0.5 2.1 2 0 0 2 2 2 1 Thioredoxin-like domain CBM_1 PF00734.18 OQS03544.1 - 1.6e-13 50.3 17.5 1.3e-07 31.5 5.3 2.9 2 0 0 2 2 2 2 Fungal cellulose binding domain Thioredoxin_15 PF18403.1 OQS03544.1 - 3.9e-08 33.5 0.8 1.3e-06 28.5 0.3 3.2 2 1 0 2 2 2 1 Thioredoxin-like domain PT PF04886.12 OQS03544.1 - 2.8e-06 26.8 98.1 0.17 11.4 11.0 5.0 3 1 0 3 3 2 1 PT repeat Glyco_transf_8 PF01501.20 OQS03544.1 - 1.9e-05 24.3 3.3 3.2e-05 23.6 0.4 2.3 2 0 0 2 2 2 1 Glycosyl transferase family 8 NADase_NGA PF07461.11 OQS03544.1 - 0.17 10.8 0.0 0.28 10.0 0.0 1.2 1 0 0 1 1 1 0 Nicotine adenine dinucleotide glycohydrolase (NADase) DUF5534 PF17686.1 OQS03545.1 - 0.035 14.4 0.0 0.043 14.1 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5534) DUF3464 PF11947.8 OQS03545.1 - 0.088 12.6 0.7 0.14 11.9 0.7 1.2 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 DSHCT PF08148.12 OQS03546.1 - 1.4e-53 180.9 0.3 2.5e-53 180.1 0.3 1.4 1 0 0 1 1 1 1 DSHCT (NUC185) domain rRNA_proc-arch PF13234.6 OQS03546.1 - 3.5e-20 73.1 0.0 5e-20 72.6 0.0 1.2 1 0 0 1 1 1 1 rRNA-processing arch domain Helicase_C PF00271.31 OQS03546.1 - 5.3e-07 30.0 0.1 4.7e-06 26.9 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 OQS03546.1 - 1.9e-06 27.7 0.0 5e-06 26.4 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase Peptidase_S8 PF00082.22 OQS03547.1 - 6e-41 140.7 3.2 8.9e-41 140.1 3.2 1.3 1 0 0 1 1 1 1 Subtilase family FA_desaturase PF00487.24 OQS03547.1 - 1.5e-30 106.9 17.8 1.5e-30 106.9 17.8 1.9 2 0 0 2 2 2 1 Fatty acid desaturase Cyt-b5 PF00173.28 OQS03547.1 - 2.2e-17 62.9 0.2 4.6e-17 61.9 0.2 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain zf-H2C2_5 PF13909.6 OQS03547.1 - 0.061 13.1 0.0 0.15 11.8 0.0 1.7 1 0 0 1 1 1 0 C2H2-type zinc-finger domain ECR1_N PF14382.6 OQS03547.1 - 0.061 13.1 0.0 4.2 7.3 0.0 2.6 2 0 0 2 2 2 0 Exosome complex exonuclease RRP4 N-terminal region zf-Di19 PF05605.12 OQS03547.1 - 0.13 12.6 0.3 0.34 11.2 0.3 1.7 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding LapA_dom PF06305.11 OQS03548.1 - 0.0037 17.0 0.4 0.0064 16.3 0.4 1.3 1 0 0 1 1 1 1 Lipopolysaccharide assembly protein A domain TNFR_16_TM PF18422.1 OQS03548.1 - 0.0063 16.4 0.2 0.01 15.8 0.2 1.4 1 0 0 1 1 1 1 Tumor necrosis factor receptor member 16 trans-membrane domain HemY_N PF07219.13 OQS03548.1 - 0.052 13.8 0.3 0.094 12.9 0.3 1.3 1 0 0 1 1 1 0 HemY protein N-terminus DUF4381 PF14316.6 OQS03548.1 - 0.058 13.6 0.0 0.09 13.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) CBP_BcsF PF11120.8 OQS03548.1 - 0.14 12.3 2.9 4 7.6 1.9 2.2 2 0 0 2 2 2 0 Cellulose biosynthesis protein BcsF Ank_2 PF12796.7 OQS03549.1 - 3e-105 345.0 33.8 1.6e-14 54.2 0.0 8.3 1 1 8 9 9 9 9 Ankyrin repeats (3 copies) Ank PF00023.30 OQS03549.1 - 6e-92 298.4 37.3 1.6e-07 31.4 0.1 15.2 15 0 0 15 15 15 15 Ankyrin repeat Ank_4 PF13637.6 OQS03549.1 - 4.9e-89 291.7 24.9 6.6e-12 45.7 0.1 13.9 4 4 11 15 15 15 15 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQS03549.1 - 1.7e-83 264.5 22.0 2e-05 24.6 0.1 14.8 15 0 0 15 15 15 14 Ankyrin repeat Ank_5 PF13857.6 OQS03549.1 - 7.7e-68 223.7 23.2 8e-10 38.8 0.3 11.1 4 3 7 12 12 12 12 Ankyrin repeats (many copies) Imm_superinfect PF14373.6 OQS03549.1 - 0.00051 19.9 16.8 14 5.7 0.0 9.7 10 0 0 10 10 10 1 Superinfection immunity protein YfmQ PF10787.9 OQS03549.1 - 0.00085 19.1 0.0 7.8 6.3 0.0 5.0 6 1 1 7 7 7 2 Uncharacterised protein from bacillus cereus group BRCA-2_OB1 PF09103.10 OQS03549.1 - 0.0023 17.9 0.5 3.5 7.6 0.0 4.0 3 1 2 5 5 5 1 BRCA2, oligonucleotide/oligosaccharide-binding, domain 1 HEM4 PF02602.15 OQS03549.1 - 0.064 12.6 0.0 2.7 7.3 0.0 3.5 4 1 2 6 6 6 0 Uroporphyrinogen-III synthase HemD DUF1940 PF09155.10 OQS03549.1 - 3.4 7.8 8.2 3.8 7.6 0.0 4.4 5 1 1 6 6 6 0 Domain of unknown function (DUF1940) Ank_2 PF12796.7 OQS03550.1 - 3.5e-74 245.4 36.2 1.2e-09 38.6 0.1 14.0 8 4 2 13 13 13 12 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQS03550.1 - 1.4e-54 181.7 32.8 2.6e-07 31.1 0.1 17.0 14 4 4 18 18 18 14 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQS03550.1 - 2.8e-51 165.5 33.9 0.0037 17.6 0.0 23.0 24 0 0 24 24 24 13 Ankyrin repeat Ank_5 PF13857.6 OQS03550.1 - 9.3e-41 137.4 35.4 0.00091 19.5 0.1 18.8 12 6 9 21 21 21 13 Ankyrin repeats (many copies) Ank PF00023.30 OQS03550.1 - 8e-29 98.8 49.2 0.0012 19.2 0.1 18.3 22 0 0 22 22 22 9 Ankyrin repeat Kinesin PF00225.23 OQS03551.1 - 5.8e-107 357.5 0.1 5.8e-107 357.5 0.1 2.4 2 0 0 2 2 2 1 Kinesin motor domain UCH PF00443.29 OQS03551.1 - 6.2e-43 147.1 1.3 6.2e-43 147.1 1.3 3.1 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 OQS03551.1 - 1.1e-25 90.9 0.6 1.1e-25 90.9 0.6 3.6 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase Microtub_bd PF16796.5 OQS03551.1 - 1e-23 83.9 0.0 1e-23 83.9 0.0 3.5 3 1 0 3 3 3 1 Microtubule binding Methyltransf_8 PF05148.15 OQS03552.1 - 2.1e-78 263.2 0.0 2.4e-78 262.9 0.0 1.0 1 0 0 1 1 1 1 Hypothetical methyltransferase Methyltransf_11 PF08241.12 OQS03552.1 - 3.9e-07 30.6 0.0 2.7e-06 28.0 0.0 2.2 1 1 1 2 2 2 1 Methyltransferase domain MTS PF05175.14 OQS03552.1 - 3.9e-05 23.3 0.0 0.0027 17.3 0.0 2.2 1 1 1 2 2 2 1 Methyltransferase small domain Methyltransf_25 PF13649.6 OQS03552.1 - 0.00026 21.6 0.0 0.0059 17.3 0.0 2.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OQS03552.1 - 0.0046 16.7 0.1 0.026 14.3 0.1 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OQS03552.1 - 0.0049 17.6 0.1 0.17 12.7 0.1 2.4 1 1 0 1 1 1 1 Methyltransferase domain K-cyclin_vir_C PF09080.10 OQS03552.1 - 0.012 16.0 0.0 0.02 15.3 0.0 1.3 1 0 0 1 1 1 0 K cyclin, C terminal Ubie_methyltran PF01209.18 OQS03552.1 - 0.085 12.2 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family KASH_CCD PF14662.6 OQS03553.1 - 0.0099 15.7 2.9 0.0099 15.7 2.9 3.5 3 1 1 4 4 4 3 Coiled-coil region of CCDC155 or KASH ATG16 PF08614.11 OQS03553.1 - 0.013 15.7 11.6 0.013 15.7 11.6 3.1 2 1 1 3 3 3 0 Autophagy protein 16 (ATG16) Fez1 PF06818.15 OQS03553.1 - 3.6 8.0 33.5 2.3 8.7 10.5 2.4 1 1 1 2 2 2 0 Fez1 RraB PF06877.11 OQS03553.1 - 5.8 7.7 8.2 1.9 9.2 3.0 2.9 1 1 0 2 2 2 0 Regulator of ribonuclease activity B DUF3138 PF11336.8 OQS03553.1 - 6.2 5.3 8.1 2.4 6.7 0.4 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3138) CENP-F_leu_zip PF10473.9 OQS03553.1 - 6.5 6.8 41.3 6.4 6.8 16.3 3.7 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 tRNA-synt_2b PF00587.25 OQS03554.1 - 1.6e-36 125.9 0.0 2.9e-36 125.1 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 OQS03554.1 - 5.5e-18 64.9 0.1 1.1e-17 63.9 0.1 1.6 1 0 0 1 1 1 1 Anticodon binding domain tRNA_SAD PF07973.14 OQS03554.1 - 7.6e-12 45.1 0.1 7.9e-11 41.9 0.0 2.4 2 0 0 2 2 2 1 Threonyl and Alanyl tRNA synthetase second additional domain TGS PF02824.21 OQS03554.1 - 2.4e-08 33.9 0.0 1.1e-07 31.7 0.0 2.3 2 1 0 2 2 2 1 TGS domain AAA_11 PF13086.6 OQS03554.1 - 0.0029 17.4 3.7 0.0048 16.7 3.7 1.3 1 0 0 1 1 1 1 AAA domain tRNA-synt_His PF13393.6 OQS03554.1 - 0.011 15.0 0.0 0.017 14.4 0.0 1.3 1 0 0 1 1 1 0 Histidyl-tRNA synthetase Paf1 PF03985.13 OQS03554.1 - 0.58 9.1 16.4 0.85 8.5 16.4 1.2 1 0 0 1 1 1 0 Paf1 CDC45 PF02724.14 OQS03554.1 - 1.6 6.9 7.4 2.2 6.5 7.4 1.2 1 0 0 1 1 1 0 CDC45-like protein Fra10Ac1 PF09725.9 OQS03555.1 - 6.1e-44 149.1 4.1 9.5e-44 148.5 4.1 1.3 1 0 0 1 1 1 1 Folate-sensitive fragile site protein Fra10Ac1 zf-tcix PF14952.6 OQS03555.1 - 0.048 13.3 5.7 0.13 11.8 0.1 2.3 2 0 0 2 2 2 0 Putative treble-clef, zinc-finger, Zn-binding ASH PF15780.5 OQS03556.1 - 6.3e-32 109.7 21.3 0.00052 20.2 0.2 14.1 17 0 0 17 17 17 8 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin PapD-like PF14874.6 OQS03556.1 - 1.9e-10 40.8 0.5 0.18 11.9 0.0 6.0 5 0 0 5 5 5 3 Flagellar-associated PapD-like Motile_Sperm PF00635.26 OQS03556.1 - 3.7e-07 30.0 3.4 0.11 12.4 0.1 7.8 8 1 0 8 8 8 1 MSP (Major sperm protein) domain TMEM131_like PF12371.8 OQS03556.1 - 6.5e-06 26.3 18.7 1.7 9.0 0.2 9.5 13 1 1 14 14 14 3 Transmembrane protein 131-like DUF1573 PF07610.11 OQS03556.1 - 0.0004 20.3 0.0 7.3 6.7 0.0 6.5 8 0 0 8 8 8 1 Protein of unknown function (DUF1573) CH PF00307.31 OQS03556.1 - 0.024 14.8 0.0 0.049 13.8 0.0 1.6 1 0 0 1 1 1 0 Calponin homology (CH) domain Peptidase_M24 PF00557.24 OQS03557.1 - 1.3e-49 168.8 0.0 2e-49 168.1 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 PrmA PF06325.13 OQS03557.1 - 1.8e-12 47.3 0.1 4e-12 46.1 0.1 1.5 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.6 OQS03557.1 - 1.3e-10 41.9 0.1 4.9e-09 36.8 0.0 3.1 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_11 PF08241.12 OQS03557.1 - 1.1e-09 38.8 0.1 8.2e-09 36.0 0.0 2.5 3 0 0 3 3 2 1 Methyltransferase domain MTS PF05175.14 OQS03557.1 - 5.9e-08 32.4 0.0 1.5e-07 31.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_31 PF13847.6 OQS03557.1 - 5e-07 29.6 0.0 1.3e-06 28.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain PRMT5 PF05185.16 OQS03557.1 - 1.6e-06 28.1 0.2 2.8e-06 27.3 0.2 1.3 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase Methyltransf_23 PF13489.6 OQS03557.1 - 1.8e-06 27.9 0.0 4.9e-06 26.5 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.15 OQS03557.1 - 1.5e-05 24.7 0.1 3.7e-05 23.4 0.1 1.7 1 1 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_9 PF08003.11 OQS03557.1 - 2.2e-05 23.5 0.0 3.9e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) TehB PF03848.14 OQS03557.1 - 0.00012 21.6 0.0 0.00024 20.6 0.0 1.5 1 0 0 1 1 1 1 Tellurite resistance protein TehB Methyltransf_18 PF12847.7 OQS03557.1 - 0.00015 21.8 0.1 0.00028 20.9 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OQS03557.1 - 0.00022 21.9 0.0 0.02 15.6 0.0 2.5 2 0 0 2 2 2 1 Methyltransferase domain Met_10 PF02475.16 OQS03557.1 - 0.00043 20.1 0.1 0.00073 19.3 0.1 1.3 1 0 0 1 1 1 1 Met-10+ like-protein GidB PF02527.15 OQS03557.1 - 0.0035 16.7 0.0 0.0065 15.8 0.0 1.3 1 0 0 1 1 1 1 rRNA small subunit methyltransferase G CMAS PF02353.20 OQS03557.1 - 0.0094 15.3 0.0 0.016 14.5 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_16 PF10294.9 OQS03557.1 - 0.044 13.5 0.0 0.08 12.7 0.0 1.3 1 0 0 1 1 1 0 Lysine methyltransferase Methyltransf_24 PF13578.6 OQS03557.1 - 0.066 14.2 0.0 0.15 13.1 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Rsm22 PF09243.10 OQS03557.1 - 0.068 12.4 0.1 0.12 11.7 0.1 1.3 1 0 0 1 1 1 0 Mitochondrial small ribosomal subunit Rsm22 PCMT PF01135.19 OQS03557.1 - 0.12 12.1 0.1 0.23 11.2 0.1 1.4 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) SKG6 PF08693.10 OQS03557.1 - 0.2 11.1 0.9 0.35 10.3 0.9 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Prenyltrans PF00432.21 OQS03558.1 - 4.8e-23 80.6 7.4 6.1e-06 25.9 0.1 6.2 6 0 0 6 6 6 6 Prenyltransferase and squalene oxidase repeat Adap_comp_sub PF00928.21 OQS03559.1 - 6.7e-81 271.5 0.0 1e-80 270.9 0.0 1.3 1 0 0 1 1 1 1 Adaptor complexes medium subunit family muHD PF10291.9 OQS03559.1 - 0.01 15.3 0.0 0.027 13.9 0.0 1.7 1 0 0 1 1 1 0 Muniscin C-terminal mu homology domain UAA PF08449.11 OQS03560.1 - 7.5e-65 219.1 16.0 9.9e-65 218.7 16.0 1.1 1 0 0 1 1 1 1 UAA transporter family PH PF00169.29 OQS03560.1 - 4.4e-18 65.7 0.2 8.3e-18 64.8 0.2 1.5 1 0 0 1 1 1 1 PH domain EamA PF00892.20 OQS03560.1 - 2.4e-08 34.2 21.3 0.00066 19.9 9.5 2.6 2 2 0 2 2 2 2 EamA-like transporter family TPT PF03151.16 OQS03560.1 - 3e-07 30.1 9.6 1.9e-05 24.2 1.2 2.3 2 0 0 2 2 2 2 Triose-phosphate Transporter family Nuc_sug_transp PF04142.15 OQS03560.1 - 6.1e-05 22.3 6.5 0.0019 17.5 0.5 2.4 1 1 1 2 2 2 2 Nucleotide-sugar transporter PH_8 PF15409.6 OQS03560.1 - 0.00042 20.5 0.0 0.00089 19.5 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain PH_11 PF15413.6 OQS03560.1 - 0.0012 19.2 3.9 0.059 13.8 3.9 2.5 1 1 0 1 1 1 1 Pleckstrin homology domain PH_9 PF15410.6 OQS03560.1 - 0.014 15.7 0.8 0.3 11.5 0.8 2.3 1 1 0 1 1 1 0 Pleckstrin homology domain PH_16 PF17838.1 OQS03560.1 - 0.13 12.1 0.0 0.36 10.7 0.0 1.7 2 0 0 2 2 2 0 PH domain Ubiquitin_4 PF18036.1 OQS03562.1 - 0.086 12.9 0.3 5.8 7.0 0.0 3.1 3 0 0 3 3 3 0 Ubiquitin-like domain Ank_2 PF12796.7 OQS03563.1 - 4.7e-211 684.0 55.7 5.6e-19 68.5 0.1 15.4 1 1 13 16 16 16 16 Ankyrin repeats (3 copies) Ank PF00023.30 OQS03563.1 - 5.8e-187 598.9 46.8 3.4e-08 33.6 0.1 29.5 29 1 1 30 30 29 28 Ankyrin repeat Ank_3 PF13606.6 OQS03563.1 - 1.3e-175 547.5 22.5 1.1e-06 28.5 0.0 29.8 30 0 0 30 30 30 28 Ankyrin repeat Ank_4 PF13637.6 OQS03563.1 - 1.7e-169 548.2 20.6 2.1e-11 44.1 0.0 22.0 5 5 20 25 25 25 24 Ankyrin repeats (many copies) Ank_5 PF13857.6 OQS03563.1 - 3.1e-120 390.7 36.9 5.1e-09 36.2 0.1 19.2 8 6 11 20 20 20 19 Ankyrin repeats (many copies) Ribosomal_S6 PF01250.17 OQS03563.1 - 2.6e-08 34.0 2.8 22 5.4 0.0 10.7 9 4 5 14 14 14 0 Ribosomal protein S6 Arg_repressor PF01316.21 OQS03563.1 - 1e-07 31.6 21.4 15 5.4 0.0 15.4 23 0 0 23 23 22 0 Arginine repressor, DNA binding domain HEM4 PF02602.15 OQS03563.1 - 4.1e-06 26.3 0.6 13 5.0 0.0 7.2 7 1 2 9 9 9 0 Uroporphyrinogen-III synthase HemD YfmQ PF10787.9 OQS03563.1 - 3.6e-05 23.6 0.3 1.8 8.4 0.1 6.6 7 3 2 9 9 9 1 Uncharacterised protein from bacillus cereus group DUF4350 PF14258.6 OQS03563.1 - 0.00026 21.4 0.0 15 6.1 0.0 6.7 6 1 0 6 6 6 0 Domain of unknown function (DUF4350) DZR PF12773.7 OQS03563.1 - 0.00033 20.6 2.9 0.00099 19.1 3.0 1.8 1 1 0 1 1 1 1 Double zinc ribbon Mqo PF06039.15 OQS03563.1 - 0.00072 18.2 0.0 3.1 6.2 0.0 4.3 4 1 1 5 5 5 1 Malate:quinone oxidoreductase (Mqo) Imm_superinfect PF14373.6 OQS03563.1 - 0.01 15.7 7.8 89 3.1 0.0 9.1 12 0 0 12 12 10 0 Superinfection immunity protein VWA_3_C PF18571.1 OQS03563.1 - 0.02 14.7 8.8 67 3.5 0.0 7.9 10 0 0 10 10 9 0 von Willebrand factor type A C-terminal domain ALF PF03752.13 OQS03563.1 - 0.13 12.2 4.2 30 4.7 0.0 5.6 7 0 0 7 7 7 0 Short repeats of unknown function CUE PF02845.16 OQS03563.1 - 2.3 8.0 28.2 21 4.9 0.1 11.1 13 0 0 13 13 13 0 CUE domain zf-C4pol PF14260.6 OQS03563.1 - 2.3 8.7 7.1 14 6.3 1.1 2.4 2 0 0 2 2 2 0 C4-type zinc-finger of DNA polymerase delta Ank_2 PF12796.7 OQS03564.1 - 6.4e-21 74.7 0.1 1.6e-15 57.5 0.0 3.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 OQS03564.1 - 2.5e-19 68.8 0.1 2.1e-05 24.7 0.0 4.3 4 0 0 4 4 4 3 Ankyrin repeat Ank_3 PF13606.6 OQS03564.1 - 5.6e-17 60.1 0.1 5.5e-05 23.3 0.0 4.7 5 0 0 5 5 5 3 Ankyrin repeat Ank_4 PF13637.6 OQS03564.1 - 8.4e-16 58.1 0.1 9e-07 29.3 0.0 3.7 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 OQS03564.1 - 3.2e-09 36.8 0.1 0.0038 17.5 0.0 3.9 2 1 2 4 4 4 3 Ankyrin repeats (many copies) RNase_PH_C PF03725.15 OQS03564.1 - 0.042 13.9 0.1 19 5.4 0.0 3.3 3 0 0 3 3 3 0 3' exoribonuclease family, domain 2 Pkinase PF00069.25 OQS03565.1 - 1.2e-11 44.5 0.0 1.6e-11 44.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQS03565.1 - 1.5e-09 37.5 0.0 2.2e-09 37.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase DUF21 PF01595.20 OQS03566.1 - 1.7e-27 96.3 1.6 2.5e-27 95.7 1.6 1.2 1 0 0 1 1 1 1 Cyclin M transmembrane N-terminal domain CBS PF00571.28 OQS03566.1 - 9.3e-05 22.8 2.1 0.14 12.6 0.3 3.0 2 1 0 2 2 2 2 CBS domain p450 PF00067.22 OQS03567.1 - 1.9e-73 247.8 0.0 2.2e-73 247.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 ABC_membrane PF00664.23 OQS03568.1 - 4.3e-62 210.3 18.3 2.6e-32 112.6 8.6 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 OQS03568.1 - 2.7e-17 63.6 0.0 4.3e-17 62.9 0.0 1.4 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 OQS03568.1 - 2.6e-06 27.1 0.4 0.00046 19.7 0.4 2.2 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain ApoO PF09769.9 OQS03568.1 - 0.032 14.2 0.1 0.27 11.2 0.0 2.3 2 0 0 2 2 2 0 Apolipoprotein O Dynamin_N PF00350.23 OQS03568.1 - 0.058 13.4 0.5 0.12 12.4 0.5 1.5 1 0 0 1 1 1 0 Dynamin family AAA_29 PF13555.6 OQS03568.1 - 0.069 12.9 0.1 0.15 11.9 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_21 PF13304.6 OQS03568.1 - 0.075 12.8 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system T2SSE PF00437.20 OQS03568.1 - 0.083 11.9 0.0 0.16 11.0 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_22 PF13401.6 OQS03568.1 - 0.1 12.9 0.1 0.27 11.5 0.1 1.7 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 OQS03568.1 - 0.16 12.1 0.0 0.33 11.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 OQS03568.1 - 0.17 12.0 0.0 0.41 10.7 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase eIF3_p135 PF12807.7 OQS03569.1 - 1.1e-15 58.1 0.1 3.4e-15 56.5 0.1 1.8 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit 135 PH PF00169.29 OQS03569.1 - 2.9e-09 37.4 0.4 7.1e-09 36.1 0.4 1.7 1 0 0 1 1 1 1 PH domain TPR_12 PF13424.6 OQS03569.1 - 2.1e-08 34.3 11.1 1.3e-05 25.4 0.0 3.9 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_MalT PF17874.1 OQS03569.1 - 9.9e-07 28.4 14.7 0.00048 19.6 4.9 2.8 2 1 0 3 3 3 2 MalT-like TPR region TPR_2 PF07719.17 OQS03569.1 - 1.1e-05 25.2 7.9 1.5 9.2 0.1 5.9 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_7 PF13176.6 OQS03569.1 - 1.1e-05 25.0 2.9 0.68 10.1 0.0 5.0 5 0 0 5 5 4 2 Tetratricopeptide repeat CLU PF13236.6 OQS03569.1 - 3.6e-05 23.7 0.0 0.00036 20.4 0.0 2.4 2 1 0 2 2 2 1 Clustered mitochondria TPR_1 PF00515.28 OQS03569.1 - 0.00071 19.3 5.5 0.77 9.7 0.0 5.1 5 0 0 5 5 5 1 Tetratricopeptide repeat CPV_Polyhedrin PF17515.2 OQS03569.1 - 0.032 13.6 0.1 0.056 12.8 0.1 1.3 1 0 0 1 1 1 0 Cypovirus polyhedrin TPR_10 PF13374.6 OQS03569.1 - 0.035 14.0 4.5 1.1 9.2 0.0 3.9 5 0 0 5 5 5 0 Tetratricopeptide repeat DUF1871 PF08958.10 OQS03569.1 - 0.13 12.6 0.5 0.99 9.8 0.2 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1871) TPR_6 PF13174.6 OQS03569.1 - 0.37 11.5 2.9 53 4.8 0.0 4.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 OQS03569.1 - 0.39 11.1 9.6 6.7 7.2 0.0 4.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_16 PF13432.6 OQS03569.1 - 9.4 7.0 8.6 45 4.8 0.1 4.0 5 0 0 5 5 5 0 Tetratricopeptide repeat Ank_4 PF13637.6 OQS03570.1 - 2.3e-11 44.0 3.9 2.1e-06 28.2 0.2 2.0 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 OQS03570.1 - 5.2e-07 30.2 0.7 0.00033 21.2 0.1 1.8 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OQS03570.1 - 8.7e-05 22.6 0.1 0.22 12.2 0.0 2.5 2 1 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.6 OQS03570.1 - 0.00044 20.5 0.1 0.31 11.4 0.0 2.2 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 OQS03570.1 - 0.0079 16.6 0.1 0.9 10.1 0.0 2.3 2 0 0 2 2 2 1 Ankyrin repeat NanE PF04131.14 OQS03570.1 - 0.013 14.7 0.2 0.019 14.2 0.0 1.3 2 0 0 2 2 2 0 Putative N-acetylmannosamine-6-phosphate epimerase DUF1843 PF08898.10 OQS03570.1 - 0.079 13.5 0.1 3.6 8.2 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1843) Pkinase_Tyr PF07714.17 OQS03571.1 - 3.7e-31 108.4 0.0 6.3e-31 107.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OQS03571.1 - 1.8e-30 106.2 0.7 3e-30 105.5 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain C2 PF00168.30 OQS03571.1 - 4.7e-10 39.7 0.0 9.4e-10 38.7 0.0 1.5 1 0 0 1 1 1 1 C2 domain Kdo PF06293.14 OQS03571.1 - 2.1e-05 24.0 0.0 4.1e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family DZR PF12773.7 OQS03571.1 - 0.0022 18.0 0.5 0.0047 16.9 0.5 1.6 1 1 0 1 1 1 1 Double zinc ribbon MAD PF05557.13 OQS03571.1 - 0.018 13.4 2.4 0.03 12.7 2.4 1.2 1 0 0 1 1 1 0 Mitotic checkpoint protein Kinase-like PF14531.6 OQS03571.1 - 0.036 13.4 0.0 0.073 12.4 0.0 1.4 1 0 0 1 1 1 0 Kinase-like GPS2_interact PF15784.5 OQS03571.1 - 0.069 13.6 1.1 0.16 12.5 1.1 1.5 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain Med4 PF10018.9 OQS03571.1 - 0.092 12.4 2.5 0.15 11.7 2.5 1.3 1 0 0 1 1 1 0 Vitamin-D-receptor interacting Mediator subunit 4 zf-C4pol PF14260.6 OQS03571.1 - 0.28 11.7 5.5 1.3 9.5 0.7 2.7 2 0 0 2 2 2 0 C4-type zinc-finger of DNA polymerase delta Spc7 PF08317.11 OQS03571.1 - 1.9 7.3 7.5 0.24 10.3 3.2 1.6 2 0 0 2 2 2 0 Spc7 kinetochore protein Filament PF00038.21 OQS03572.1 - 0.045 13.3 10.4 0.2 11.2 10.4 1.8 1 1 0 1 1 1 0 Intermediate filament protein DUF4795 PF16043.5 OQS03572.1 - 0.05 13.2 11.0 0.095 12.3 9.8 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4795) Fungal_TACC PF12709.7 OQS03572.1 - 0.12 12.8 7.0 3.9 8.0 0.1 3.4 2 1 1 3 3 3 0 Fungal Transforming acidic coiled-coil (TACC) proteins TPD52 PF04201.15 OQS03572.1 - 0.21 11.2 2.3 0.36 10.4 0.8 2.1 2 1 1 3 3 3 0 Tumour protein D52 family Bap31_Bap29_C PF18035.1 OQS03572.1 - 0.33 11.0 6.0 5.1 7.2 0.2 2.5 2 0 0 2 2 2 0 Bap31/Bap29 cytoplasmic coiled-coil domain FapA PF03961.13 OQS03572.1 - 1.1 7.8 4.7 1.6 7.2 4.7 1.3 1 0 0 1 1 1 0 Flagellar Assembly Protein A TMF_DNA_bd PF12329.8 OQS03572.1 - 1.3 9.1 5.2 1.9 8.6 3.0 2.4 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding ACCA PF03255.14 OQS03572.1 - 2.4 8.0 5.3 2.8 7.8 0.3 2.4 1 1 1 2 2 2 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit CC2-LZ PF16516.5 OQS03572.1 - 5.4 7.5 10.3 4.1 7.8 2.6 2.6 1 1 2 3 3 3 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator Ank_2 PF12796.7 OQS03573.1 - 3.1e-74 245.6 9.1 7.6e-13 48.9 0.0 7.4 2 2 6 8 8 8 8 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQS03573.1 - 1.1e-59 198.1 5.5 1.9e-08 34.6 0.1 11.9 6 3 6 12 12 12 12 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQS03573.1 - 1.5e-51 166.3 6.8 0.0011 19.3 0.0 14.8 15 0 0 15 15 14 11 Ankyrin repeat Pkinase PF00069.25 OQS03573.1 - 3.3e-51 174.2 0.0 5.7e-51 173.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Ank_5 PF13857.6 OQS03573.1 - 8.7e-50 166.1 12.5 9.1e-08 32.2 0.0 10.7 3 2 8 11 11 11 10 Ankyrin repeats (many copies) Pkinase_Tyr PF07714.17 OQS03573.1 - 8e-44 149.9 0.0 1.2e-43 149.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Ank PF00023.30 OQS03573.1 - 6.1e-42 140.3 23.5 0.00039 20.7 0.1 14.1 15 0 0 15 15 15 10 Ankyrin repeat Pkinase_fungal PF17667.1 OQS03573.1 - 0.0016 17.3 0.1 0.055 12.2 0.0 2.2 2 0 0 2 2 2 1 Fungal protein kinase Haspin_kinase PF12330.8 OQS03573.1 - 0.0045 16.0 0.0 0.015 14.3 0.0 1.7 2 0 0 2 2 2 1 Haspin like kinase domain Kdo PF06293.14 OQS03573.1 - 0.011 15.1 0.0 0.02 14.3 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family HCV_env PF01539.17 OQS03573.1 - 0.034 13.9 0.3 1.2 8.8 0.0 2.3 2 0 0 2 2 2 0 Hepatitis C virus envelope glycoprotein E1 Lipase_GDSL_2 PF13472.6 OQS03574.1 - 2e-10 41.3 0.0 3.1e-10 40.8 0.0 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family CE2_N PF17996.1 OQS03574.1 - 3.4e-10 39.9 0.1 9.9e-10 38.4 0.0 1.8 2 0 0 2 2 2 1 Carbohydrate esterase 2 N-terminal Lipase_GDSL PF00657.22 OQS03574.1 - 0.11 12.4 0.0 0.19 11.7 0.0 1.4 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase ABC_tran PF00005.27 OQS03575.1 - 9.7e-27 94.1 0.0 2.5e-26 92.8 0.0 1.8 1 0 0 1 1 1 1 ABC transporter ABC2_membrane_3 PF12698.7 OQS03575.1 - 1.1e-19 70.8 18.9 1.3e-19 70.6 15.3 2.2 2 0 0 2 2 2 1 ABC-2 family transporter protein AAA_21 PF13304.6 OQS03575.1 - 4.9e-10 39.7 0.1 4.1e-07 30.1 0.0 2.4 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 OQS03575.1 - 0.0011 18.8 0.7 0.071 12.8 0.0 3.1 3 0 0 3 3 3 1 AAA ATPase domain DUF4140 PF13600.6 OQS03575.1 - 0.038 14.4 0.2 0.1 13.0 0.2 1.7 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) Glyco_hydro_85 PF03644.13 OQS03576.1 - 7e-10 38.8 0.6 3.1e-09 36.7 0.2 2.1 1 1 1 2 2 2 1 Glycosyl hydrolase family 85 RVT_1 PF00078.27 OQS03578.1 - 1.4e-16 60.7 0.1 5.1e-16 58.9 0.0 1.8 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) S6PP_C PF08472.10 OQS03578.1 - 0.16 11.9 0.0 0.55 10.1 0.0 1.9 2 0 0 2 2 2 0 Sucrose-6-phosphate phosphohydrolase C-terminal TTL PF03133.15 OQS03579.1 - 5.9e-43 147.1 0.8 9.5e-43 146.4 0.8 1.2 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family EGF_Tenascin PF18720.1 OQS03579.1 - 0.0014 18.6 8.4 0.0033 17.4 8.4 1.6 1 0 0 1 1 1 1 Tenascin EGF domain ATPgrasp_YheCD PF14398.6 OQS03579.1 - 0.0016 17.7 0.0 0.0031 16.8 0.0 1.4 1 0 0 1 1 1 1 YheC/D like ATP-grasp Dala_Dala_lig_C PF07478.13 OQS03579.1 - 0.037 13.6 0.0 0.062 12.8 0.0 1.3 1 0 0 1 1 1 0 D-ala D-ala ligase C-terminus EB PF01683.18 OQS03579.1 - 0.043 14.1 5.5 0.11 12.8 5.5 1.6 1 0 0 1 1 1 0 EB module EGF PF00008.27 OQS03579.1 - 2 8.8 10.7 4.3 7.7 10.7 1.6 1 0 0 1 1 1 0 EGF-like domain DUF2828 PF11443.8 OQS03580.1 - 4.2e-105 352.2 1.1 9.7e-84 281.6 0.8 3.0 1 1 0 2 2 2 2 Domain of unknown function (DUF2828) VWA_CoxE PF05762.14 OQS03580.1 - 0.028 13.8 0.1 0.13 11.6 0.1 2.0 1 1 0 1 1 1 0 VWA domain containing CoxE-like protein VWA_2 PF13519.6 OQS03580.1 - 0.045 14.4 0.0 0.15 12.7 0.0 1.9 1 0 0 1 1 1 0 von Willebrand factor type A domain Ank_2 PF12796.7 OQS03581.1 - 2.4e-66 220.3 18.3 8.1e-17 61.6 0.1 7.5 2 2 3 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQS03581.1 - 7.5e-56 185.8 12.5 2.1e-10 40.9 0.0 9.0 5 3 4 9 9 9 8 Ankyrin repeats (many copies) Ank PF00023.30 OQS03581.1 - 4.8e-54 178.6 23.4 1.9e-06 28.1 0.0 12.6 13 0 0 13 13 13 11 Ankyrin repeat Ank_3 PF13606.6 OQS03581.1 - 1e-47 154.5 11.4 0.00081 19.7 0.0 12.8 12 1 1 13 13 13 11 Ankyrin repeat Ank_5 PF13857.6 OQS03581.1 - 1.8e-42 142.8 14.0 2.6e-08 33.9 0.0 10.0 3 2 8 11 11 11 10 Ankyrin repeats (many copies) ResB PF05140.14 OQS03581.1 - 0.1 11.4 0.0 0.17 10.5 0.0 1.4 1 0 0 1 1 1 0 ResB-like family UT PF03253.14 OQS03583.1 - 8.2e-71 238.5 34.1 9.6e-71 238.3 34.1 1.0 1 0 0 1 1 1 1 Urea transporter Choline_transpo PF04515.12 OQS03584.1 - 3.8e-68 230.1 28.5 3.8e-68 230.1 28.5 2.7 1 1 1 2 2 2 1 Plasma-membrane choline transporter Podoplanin PF05808.11 OQS03585.1 - 4.7 7.3 10.4 0.56 10.3 5.7 1.9 2 0 0 2 2 2 0 Podoplanin TMEM154 PF15102.6 OQS03585.1 - 9.3 6.2 10.4 74 3.2 9.7 2.6 1 1 0 1 1 1 0 TMEM154 protein family DNA_pol_A PF00476.20 OQS03587.1 - 4.1e-76 256.5 0.8 1.2e-74 251.6 0.1 2.8 1 1 1 2 2 2 1 DNA polymerase family A DNA_pol_A_exo1 PF01612.20 OQS03587.1 - 7.8e-09 35.5 0.0 3.6e-08 33.3 0.0 2.2 1 1 0 1 1 1 1 3'-5' exonuclease TPR_1 PF00515.28 OQS03588.1 - 2.2e-21 74.7 1.5 5.1e-09 35.6 0.1 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat cNMP_binding PF00027.29 OQS03588.1 - 3e-21 75.3 0.3 4.7e-10 39.4 0.0 3.5 3 0 0 3 3 3 3 Cyclic nucleotide-binding domain TPR_2 PF07719.17 OQS03588.1 - 3.3e-19 67.4 2.4 8.3e-08 31.8 0.0 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.6 OQS03588.1 - 4.4e-14 51.4 2.9 3e-06 27.0 0.1 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 OQS03588.1 - 4.7e-11 42.2 3.1 6.3e-06 25.8 0.1 3.4 2 1 1 3 3 3 2 TPR repeat TPR_17 PF13431.6 OQS03588.1 - 1e-09 38.1 3.4 7e-05 22.9 0.0 3.8 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_9 PF13371.6 OQS03588.1 - 4.4e-08 33.1 0.0 0.0029 17.7 0.0 3.2 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 OQS03588.1 - 3.8e-07 30.3 1.7 0.0023 18.2 0.2 2.6 1 1 1 2 2 2 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 OQS03588.1 - 1.1e-06 28.6 0.7 0.00046 20.2 0.0 2.8 2 1 1 3 3 3 1 Fis1 C-terminal tetratricopeptide repeat TPR_16 PF13432.6 OQS03588.1 - 1.2e-06 29.1 0.1 0.00091 19.8 0.0 2.5 1 1 0 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.6 OQS03588.1 - 1.7e-06 28.2 0.3 0.89 10.3 0.0 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat SRP_TPR_like PF17004.5 OQS03588.1 - 0.00035 20.6 1.4 0.0058 16.6 0.6 2.5 1 1 1 2 2 2 1 Putative TPR-like repeat TPR_14 PF13428.6 OQS03588.1 - 0.00043 20.9 0.1 1.3 10.1 0.0 3.4 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 OQS03588.1 - 0.0034 17.3 0.2 1.6 9.0 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_10 PF13374.6 OQS03588.1 - 0.0045 16.8 1.9 19 5.3 0.1 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat SHNi-TPR PF10516.9 OQS03588.1 - 0.013 14.9 0.0 2.1 7.9 0.0 2.8 2 0 0 2 2 2 0 SHNi-TPR TPR_3 PF07720.12 OQS03588.1 - 0.02 14.8 0.4 3.4 7.7 0.1 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat ANAPC3 PF12895.7 OQS03588.1 - 0.05 13.8 1.2 0.96 9.7 0.7 2.5 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 DUF5044 PF16447.5 OQS03588.1 - 0.11 12.3 0.3 0.51 10.1 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF5044) CEP76-C2 PF15627.6 OQS03589.1 - 1.4e-26 92.9 0.0 6.1e-26 90.9 0.0 1.9 1 1 0 1 1 1 1 CEP76 C2 domain Transglut_core PF01841.19 OQS03589.1 - 0.025 15.0 0.0 0.055 13.9 0.0 1.6 1 0 0 1 1 1 0 Transglutaminase-like superfamily Yae1_N PF09811.9 OQS03590.1 - 6.2e-09 35.4 8.9 9e-09 34.9 8.9 1.3 1 0 0 1 1 1 1 Essential protein Yae1, N terminal PC4 PF02229.16 OQS03591.1 - 1.2e-41 140.1 5.6 5.4e-21 74.0 0.2 2.5 3 0 0 3 3 3 2 Transcriptional Coactivator p15 (PC4) DUF498 PF04430.14 OQS03591.1 - 3.4e-29 101.1 0.0 1.5e-28 99.0 0.0 2.1 2 1 0 2 2 2 1 Protein of unknown function (DUF498/DUF598) LMWPc PF01451.21 OQS03591.1 - 0.0051 17.2 0.1 1.7 9.0 0.5 2.3 2 0 0 2 2 2 2 Low molecular weight phosphotyrosine protein phosphatase DUF3335 PF11814.8 OQS03591.1 - 0.038 13.5 0.2 0.072 12.5 0.2 1.4 1 0 0 1 1 1 0 Peptidase_C39 like family Osmo_CC PF08946.10 OQS03591.1 - 0.049 13.9 2.1 0.11 12.7 0.1 2.3 2 0 0 2 2 2 0 Osmosensory transporter coiled coil SRF-TF PF00319.18 OQS03592.1 - 1.3e-22 79.0 0.2 2.7e-22 78.0 0.2 1.6 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) zf-TAZ PF02135.16 OQS03592.1 - 7.4e-12 45.6 28.3 4.2e-08 33.5 7.9 2.9 3 0 0 3 3 3 2 TAZ zinc finger TAF4 PF05236.14 OQS03592.1 - 5e-08 33.0 6.6 5e-08 33.0 6.6 2.0 2 0 0 2 2 2 1 Transcription initiation factor TFIID component TAF4 family DHquinase_II PF01220.19 OQS03592.1 - 5.8e-08 32.5 1.0 5.6e-07 29.3 1.0 2.3 1 1 0 1 1 1 1 Dehydroquinase class II SAGA-Tad1 PF12767.7 OQS03592.1 - 0.0025 17.6 2.2 0.0025 17.6 2.2 2.8 3 1 0 3 3 3 1 Transcriptional regulator of RNA polII, SAGA, subunit HLH PF00010.26 OQS03593.1 - 2.3e-09 37.1 0.6 7.8e-08 32.2 0.5 2.3 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain ZapB PF06005.12 OQS03593.1 - 0.045 14.2 0.1 0.11 13.0 0.1 1.6 1 0 0 1 1 1 0 Cell division protein ZapB Ricin_B_lectin PF00652.22 OQS03594.1 - 8.1e-21 74.6 14.7 1.2e-08 35.3 0.7 3.0 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain PT PF04886.12 OQS03594.1 - 1.4e-11 43.7 93.6 0.00057 19.4 25.2 4.5 1 1 2 3 3 3 3 PT repeat RicinB_lectin_2 PF14200.6 OQS03594.1 - 3.6e-09 37.2 4.9 0.089 13.5 0.1 4.0 2 1 2 4 4 4 3 Ricin-type beta-trefoil lectin domain-like DUF3830 PF12903.7 OQS03594.1 - 0.044 13.5 0.1 0.044 13.5 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3830) TrmO PF01980.16 OQS03595.1 - 5.8e-38 129.8 0.0 1.1e-37 128.8 0.0 1.5 1 0 0 1 1 1 1 tRNA-methyltransferase O FTCD_C PF04961.12 OQS03595.1 - 0.015 15.0 0.1 0.026 14.3 0.1 1.3 1 0 0 1 1 1 0 Formiminotransferase-cyclodeaminase ABC2_membrane PF01061.24 OQS03596.1 - 7.7e-38 130.0 23.7 1e-37 129.6 23.7 1.2 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.27 OQS03596.1 - 2.4e-26 92.9 0.0 3.8e-26 92.2 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 OQS03596.1 - 1.6e-09 38.0 0.4 2.5e-05 24.3 0.0 2.3 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 OQS03596.1 - 4.3e-05 23.5 0.0 7.6e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 RsgA GTPase ABC2_membrane_3 PF12698.7 OQS03596.1 - 0.00032 19.9 17.5 0.00032 19.9 17.5 1.7 1 1 0 1 1 1 1 ABC-2 family transporter protein SMC_N PF02463.19 OQS03596.1 - 0.001 18.6 0.1 0.023 14.2 0.1 2.2 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 OQS03596.1 - 0.0013 18.5 0.1 0.003 17.3 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.6 OQS03596.1 - 0.0061 16.9 0.0 0.01 16.2 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_23 PF13476.6 OQS03596.1 - 0.032 14.7 0.0 0.062 13.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain cobW PF02492.19 OQS03596.1 - 0.065 12.8 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_18 PF13238.6 OQS03596.1 - 0.075 13.6 0.0 0.16 12.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 OQS03596.1 - 0.087 13.0 0.0 0.17 12.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 OQS03596.1 - 0.091 13.0 0.0 0.41 10.9 0.0 2.0 2 1 0 2 2 2 0 AAA domain Dynamin_N PF00350.23 OQS03596.1 - 0.14 12.2 0.5 1.1 9.3 0.2 2.4 2 0 0 2 2 2 0 Dynamin family MMR_HSR1 PF01926.23 OQS03596.1 - 0.18 11.9 0.0 0.39 10.8 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase PT PF04886.12 OQS03597.1 - 5.9e-16 57.7 131.5 2.8e-07 30.0 27.5 7.9 2 2 5 7 7 7 5 PT repeat ABC_tran PF00005.27 OQS03598.1 - 3.6e-15 56.7 0.1 6.3e-15 55.9 0.1 1.4 1 0 0 1 1 1 1 ABC transporter ABC2_membrane PF01061.24 OQS03598.1 - 1.5e-05 24.6 1.2 2.1e-05 24.0 1.2 1.2 1 0 0 1 1 1 1 ABC-2 type transporter RsgA_GTPase PF03193.16 OQS03598.1 - 0.00014 21.8 0.1 0.00025 21.0 0.1 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_16 PF13191.6 OQS03598.1 - 0.0095 16.3 0.0 0.015 15.7 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_30 PF13604.6 OQS03598.1 - 0.025 14.3 0.0 0.064 13.0 0.0 1.6 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 OQS03598.1 - 0.034 13.9 0.1 0.076 12.8 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC2_membrane_3 PF12698.7 OQS03598.1 - 0.045 12.8 1.0 0.083 12.0 0.4 1.6 2 0 0 2 2 2 0 ABC-2 family transporter protein MMR_HSR1 PF01926.23 OQS03598.1 - 0.051 13.7 0.2 0.34 11.0 0.0 2.2 2 0 0 2 2 2 0 50S ribosome-binding GTPase Rad17 PF03215.15 OQS03598.1 - 0.057 13.3 0.0 0.1 12.5 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain ATPase_2 PF01637.18 OQS03598.1 - 0.064 13.2 0.0 0.092 12.6 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_21 PF13304.6 OQS03598.1 - 0.07 12.9 0.0 0.31 10.8 0.0 1.9 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_25 PF13481.6 OQS03598.1 - 0.08 12.5 0.0 0.39 10.3 0.1 2.0 2 0 0 2 2 2 0 AAA domain TruB-C_2 PF09157.11 OQS03599.1 - 0.081 13.0 0.0 0.15 12.1 0.0 1.4 1 0 0 1 1 1 0 Pseudouridine synthase II TruB, C-terminal Pkinase PF00069.25 OQS03600.1 - 1.2e-38 133.0 0.0 1.4e-38 132.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQS03600.1 - 3.1e-36 125.0 0.0 3.9e-36 124.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OQS03600.1 - 0.027 13.3 0.0 0.039 12.7 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase AP_endonuc_2 PF01261.24 OQS03600.1 - 0.1 12.0 0.0 0.18 11.2 0.0 1.4 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel APH PF01636.23 OQS03600.1 - 0.12 12.3 0.0 0.2 11.5 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family SKG6 PF08693.10 OQS03600.1 - 0.16 11.4 5.9 0.41 10.1 5.9 1.7 1 0 0 1 1 1 0 Transmembrane alpha-helix domain RabGAP-TBC PF00566.18 OQS03603.1 - 6.3e-37 127.3 0.1 6.3e-37 127.3 0.1 2.5 2 0 0 2 2 2 1 Rab-GTPase-TBC domain Aldo_ket_red PF00248.21 OQS03603.1 - 6.7e-07 28.8 0.1 1.6e-06 27.6 0.1 1.6 2 0 0 2 2 2 1 Aldo/keto reductase family CSS-motif PF12792.7 OQS03603.1 - 0.021 14.3 0.0 0.054 13.0 0.0 1.7 1 0 0 1 1 1 0 CSS motif domain associated with EAL WWE PF02825.20 OQS03603.1 - 0.057 14.0 0.1 0.21 12.2 0.1 2.0 1 0 0 1 1 1 0 WWE domain BRCT_2 PF16589.5 OQS03604.1 - 1.2e-12 48.1 0.1 9.8e-05 22.7 0.1 3.3 3 0 0 3 3 3 2 BRCT domain, a BRCA1 C-terminus domain zf-C3HC4_2 PF13923.6 OQS03604.1 - 1.2e-09 37.8 11.6 1.2e-09 37.8 11.6 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 OQS03604.1 - 1.2e-08 35.1 11.6 1.2e-08 35.1 11.6 2.0 2 0 0 2 2 2 1 Ring finger domain zf-RING_UBOX PF13445.6 OQS03604.1 - 1.3e-08 34.7 8.8 1.3e-08 34.7 8.8 2.2 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 OQS03604.1 - 1.6e-08 34.3 9.9 3.2e-08 33.3 9.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 OQS03604.1 - 6e-07 29.2 12.3 1.4e-06 28.1 12.3 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) BRCT PF00533.26 OQS03604.1 - 1.4e-06 28.6 0.5 4.2e-05 23.9 0.5 2.6 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain zf-RING_6 PF14835.6 OQS03604.1 - 2.6e-06 27.2 4.6 5.6e-06 26.1 4.6 1.6 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-C3HC4_4 PF15227.6 OQS03604.1 - 4.4e-06 26.7 11.7 1.9e-05 24.7 11.9 2.0 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 OQS03604.1 - 1.3e-05 25.1 10.8 2.7e-05 24.0 10.8 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-Nse PF11789.8 OQS03604.1 - 0.0011 18.7 5.8 0.0025 17.6 5.8 1.5 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-rbx1 PF12678.7 OQS03604.1 - 0.0017 18.6 5.8 0.005 17.1 5.8 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger domain Prok-RING_4 PF14447.6 OQS03604.1 - 0.0023 17.7 10.4 0.0093 15.8 10.5 2.0 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 RTT107_BRCT_5 PF16770.5 OQS03604.1 - 0.0081 16.0 0.0 0.024 14.5 0.0 2.0 2 1 0 2 2 1 1 Regulator of Ty1 transposition protein 107 BRCT domain BRCT_3 PF18428.1 OQS03604.1 - 0.013 15.6 1.6 0.046 13.8 0.0 2.5 3 0 0 3 3 2 0 BRCA1 C Terminus (BRCT) domain zf-P11 PF03854.14 OQS03604.1 - 0.018 14.7 2.0 0.018 14.7 2.0 2.5 1 1 1 2 2 2 0 P-11 zinc finger Filamin PF00630.19 OQS03604.1 - 0.041 14.7 0.0 0.093 13.6 0.0 1.6 1 0 0 1 1 1 0 Filamin/ABP280 repeat zf-RING_11 PF17123.5 OQS03604.1 - 0.12 12.2 9.3 0.25 11.1 8.1 2.2 2 0 0 2 2 2 0 RING-like zinc finger PTCB-BRCT PF12738.7 OQS03604.1 - 0.85 9.6 5.2 0.15 12.0 0.3 2.3 3 0 0 3 3 2 0 twin BRCT domain zf-RING_10 PF16685.5 OQS03604.1 - 8.7 6.6 11.2 3.7 7.8 7.8 2.1 2 0 0 2 2 2 0 zinc RING finger of MSL2 SprT-like PF10263.9 OQS03606.1 - 1.2e-27 96.0 0.0 1.8e-27 95.4 0.0 1.2 1 0 0 1 1 1 1 SprT-like family PIN_6 PF17146.4 OQS03607.1 - 2.5e-27 95.2 0.1 2.5e-27 95.2 0.1 1.9 2 0 0 2 2 2 1 PIN domain of ribonuclease NOB1_Zn_bind PF08772.11 OQS03607.1 - 2.6e-27 94.8 1.2 5e-27 93.9 1.2 1.5 1 0 0 1 1 1 1 Nin one binding (NOB1) Zn-ribbon like zf-CCCH_4 PF18044.1 OQS03607.1 - 2.3e-08 33.7 7.9 0.00026 20.7 0.9 2.4 2 0 0 2 2 2 2 CCCH-type zinc finger zf-CCCH PF00642.24 OQS03607.1 - 2.7e-08 33.5 6.9 0.0013 18.6 0.6 2.3 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.6 OQS03607.1 - 0.0035 17.7 9.8 0.057 13.9 2.6 2.5 2 0 0 2 2 2 2 RNA-binding, Nab2-type zinc finger zf_CCCH_4 PF18345.1 OQS03607.1 - 0.0053 16.8 16.7 0.024 14.7 1.3 3.0 3 0 0 3 3 3 2 Zinc finger domain zf-CCCH_3 PF15663.5 OQS03607.1 - 0.015 15.5 2.0 0.18 12.0 2.0 2.2 1 1 0 1 1 1 0 Zinc-finger containing family Spc7_N PF15402.6 OQS03607.1 - 0.021 13.1 3.9 0.03 12.6 3.9 1.1 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 Torus PF16131.5 OQS03607.1 - 0.039 14.6 3.0 8.8 7.1 0.1 3.1 2 1 1 3 3 3 0 Torus domain zf-C3H1 PF10650.9 OQS03607.1 - 0.11 12.3 3.6 0.2 11.4 0.4 2.5 2 0 0 2 2 2 0 Putative zinc-finger domain Ank_2 PF12796.7 OQS03610.1 - 3.2e-32 111.0 0.2 8.8e-15 55.1 0.1 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 OQS03610.1 - 1.7e-30 104.1 0.1 1e-06 28.9 0.0 4.0 4 0 0 4 4 4 4 Ankyrin repeat Ank_4 PF13637.6 OQS03610.1 - 5.2e-26 90.7 0.0 2.4e-09 37.6 0.0 2.7 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQS03610.1 - 6.8e-25 84.4 0.0 3.1e-05 24.0 0.0 4.1 4 0 0 4 4 4 4 Ankyrin repeat Ank_5 PF13857.6 OQS03610.1 - 5.1e-18 64.9 0.0 6.7e-05 23.1 0.0 3.9 1 1 3 4 4 4 4 Ankyrin repeats (many copies) DUF4541 PF15074.6 OQS03610.1 - 0.1 13.2 0.0 1.2 9.8 0.0 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4541) ABC2_membrane PF01061.24 OQS03612.1 - 1.3e-31 109.7 27.5 1.9e-31 109.1 27.5 1.3 1 0 0 1 1 1 1 ABC-2 type transporter ABC2_membrane_3 PF12698.7 OQS03612.1 - 0.0048 16.0 23.6 0.009 15.2 23.6 1.6 1 1 0 1 1 1 1 ABC-2 family transporter protein PDR_CDR PF06422.12 OQS03612.1 - 0.055 13.4 0.1 0.055 13.4 0.1 3.3 3 1 1 4 4 4 0 CDR ABC transporter DUF4097 PF13349.6 OQS03613.1 - 0.011 15.1 9.8 0.32 10.3 3.8 2.8 1 1 0 2 2 2 0 Putative adhesin Hydrolase_4 PF12146.8 OQS03614.1 - 2.4e-07 30.3 0.0 0.0023 17.2 0.0 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 OQS03614.1 - 1.1e-05 25.1 0.0 4.9e-05 22.9 0.0 1.9 1 1 1 2 2 2 1 Prolyl oligopeptidase family FSH1 PF03959.13 OQS03614.1 - 5.6e-05 22.9 0.1 0.00058 19.6 0.1 2.1 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_1 PF00561.20 OQS03614.1 - 0.00036 20.3 0.0 0.78 9.3 0.0 2.1 1 1 0 2 2 2 2 alpha/beta hydrolase fold Peptidase_S15 PF02129.18 OQS03614.1 - 0.0012 18.5 0.0 0.0072 16.0 0.0 1.9 1 1 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_2 PF02230.16 OQS03614.1 - 0.0087 15.9 0.2 0.86 9.4 0.0 2.4 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase DAO PF01266.24 OQS03615.1 - 5.4e-42 144.6 0.6 6.1e-42 144.5 0.6 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_7 PF13241.6 OQS03615.1 - 0.0015 19.0 0.0 0.0029 18.0 0.0 1.4 1 0 0 1 1 1 1 Putative NAD(P)-binding FAD_binding_2 PF00890.24 OQS03615.1 - 0.0027 16.9 0.2 0.0039 16.3 0.2 1.2 1 0 0 1 1 1 1 FAD binding domain FAD_binding_3 PF01494.19 OQS03615.1 - 0.0051 16.1 0.0 0.057 12.6 0.0 2.2 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.14 OQS03615.1 - 0.011 15.0 0.0 0.069 12.4 0.0 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 OQS03615.1 - 0.018 15.0 0.1 0.06 13.3 0.0 1.8 2 0 0 2 2 2 0 FAD-NAD(P)-binding Pyr_redox PF00070.27 OQS03615.1 - 0.07 13.7 0.1 0.14 12.7 0.1 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OQS03615.1 - 0.091 13.0 0.3 0.32 11.2 0.3 2.0 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 OQS03615.1 - 0.11 11.8 0.1 0.17 11.1 0.1 1.3 1 0 0 1 1 1 0 Thi4 family UDPG_MGDP_dh_N PF03721.14 OQS03615.1 - 0.21 11.2 0.9 0.52 9.8 0.3 1.8 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain TPR_12 PF13424.6 OQS03616.1 - 3e-11 43.4 8.7 2.7e-06 27.6 1.1 4.4 3 1 2 5 5 5 4 Tetratricopeptide repeat TPR_2 PF07719.17 OQS03616.1 - 3.5e-09 36.1 12.1 0.0026 17.8 0.5 5.8 6 1 0 6 6 6 2 Tetratricopeptide repeat TPR_8 PF13181.6 OQS03616.1 - 4.4e-09 35.8 3.3 0.4 11.0 0.2 5.4 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_10 PF13374.6 OQS03616.1 - 1.1e-08 34.6 7.5 9.1e-05 22.2 0.1 4.8 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_1 PF00515.28 OQS03616.1 - 1.4e-08 34.2 6.9 0.00015 21.5 0.3 5.3 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_14 PF13428.6 OQS03616.1 - 1.8e-08 34.5 4.4 0.22 12.4 0.0 6.4 5 2 2 7 7 7 1 Tetratricopeptide repeat TPR_6 PF13174.6 OQS03616.1 - 2.1e-06 28.0 4.3 0.19 12.4 0.0 5.3 6 0 0 6 6 4 1 Tetratricopeptide repeat TPR_7 PF13176.6 OQS03616.1 - 0.00013 21.7 1.0 0.015 15.2 0.1 3.5 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 OQS03616.1 - 0.00015 22.3 1.4 16 6.2 0.1 4.8 4 2 1 5 5 5 0 Tetratricopeptide repeat TPR_19 PF14559.6 OQS03616.1 - 0.00026 21.4 7.1 0.24 11.9 0.2 3.9 3 1 0 4 4 4 2 Tetratricopeptide repeat ANAPC3 PF12895.7 OQS03616.1 - 0.0091 16.2 6.2 2.6 8.3 0.0 4.1 2 1 2 4 4 4 1 Anaphase-promoting complex, cyclosome, subunit 3 SPOB_a PF14689.6 OQS03616.1 - 0.014 15.1 0.2 4.5 7.0 0.0 3.9 5 0 0 5 5 5 0 Sensor_kinase_SpoOB-type, alpha-helical domain TPR_17 PF13431.6 OQS03616.1 - 0.017 15.4 7.3 3.1 8.4 0.2 5.1 5 2 2 7 7 6 0 Tetratricopeptide repeat Prok-TraM PF09228.10 OQS03616.1 - 0.028 14.8 0.5 3 8.3 0.1 3.0 3 0 0 3 3 3 0 Prokaryotic Transcriptional repressor TraM TPR_11 PF13414.6 OQS03616.1 - 0.13 12.0 0.9 3 7.6 0.1 3.4 4 0 0 4 4 4 0 TPR repeat DUF2225 PF09986.9 OQS03616.1 - 1.1 8.9 4.0 0.96 9.1 0.7 2.3 2 1 1 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2225) TPR_4 PF07721.14 OQS03616.1 - 1.8 9.4 7.7 48 5.0 0.1 5.1 5 0 0 5 5 5 0 Tetratricopeptide repeat Ank_2 PF12796.7 OQS03617.1 - 1.2e-17 64.3 13.2 4.6e-10 39.9 0.5 3.5 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQS03617.1 - 1.3e-15 57.5 16.2 2.1e-05 25.0 0.1 5.2 3 2 1 5 5 5 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 OQS03617.1 - 1.6e-11 44.2 11.5 0.0012 19.1 0.1 6.3 1 1 5 6 6 6 4 Ankyrin repeats (many copies) WW PF00397.26 OQS03617.1 - 1.6e-05 24.9 3.2 3.5e-05 23.8 3.2 1.5 1 0 0 1 1 1 1 WW domain Ank_3 PF13606.6 OQS03617.1 - 5.6e-05 23.2 15.4 8.7 7.3 0.0 7.7 5 2 3 8 8 8 2 Ankyrin repeat DnaJ PF00226.31 OQS03617.1 - 0.002 18.2 0.1 0.0068 16.5 0.1 1.9 1 0 0 1 1 1 1 DnaJ domain PX PF00787.24 OQS03617.1 - 0.022 14.7 0.1 0.11 12.5 0.0 2.3 3 0 0 3 3 3 0 PX domain YmaF PF12788.7 OQS03617.1 - 1.7 9.3 19.1 0.33 11.5 3.3 3.1 3 0 0 3 3 3 0 YmaF family Ank PF00023.30 OQS03617.1 - 4.6 7.9 10.6 1.3e+02 3.3 0.0 5.9 3 2 1 4 4 4 0 Ankyrin repeat Pep1_7 PF17232.2 OQS03617.1 - 5.7 7.5 6.7 9 6.8 0.2 2.7 2 0 0 2 2 2 0 Elicitor peptide 1-7 Mito_carr PF00153.27 OQS03618.1 - 2.7e-57 190.7 4.3 2.3e-18 65.9 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein TauD PF02668.16 OQS03619.1 - 7.8e-32 111.1 0.1 1.2e-31 110.5 0.1 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF971 PF06155.12 OQS03619.1 - 2.6e-13 50.4 0.5 1.8e-12 47.7 0.3 2.4 2 1 1 3 3 3 2 Protein of unknown function (DUF971) FYVE PF01363.21 OQS03619.1 - 2.2e-05 24.5 9.7 2.2e-05 24.5 9.7 2.5 3 0 0 3 3 3 1 FYVE zinc finger CsiD PF08943.10 OQS03619.1 - 0.1 11.7 0.1 0.23 10.6 0.1 1.5 2 0 0 2 2 2 0 CsiD Gal_Lectin PF02140.18 OQS03620.1 - 4.7e-32 110.2 5.7 2e-15 57.0 0.2 2.2 2 0 0 2 2 2 2 Galactose binding lectin domain Hydrolase PF00702.26 OQS03621.1 - 9e-13 49.0 0.0 3.3e-06 27.6 0.0 2.4 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 OQS03621.1 - 1e-12 47.9 4.4 5.7e-11 42.3 0.1 3.8 2 1 0 2 2 2 1 E1-E2 ATPase Cation_ATPase PF13246.6 OQS03621.1 - 0.013 15.6 0.0 0.028 14.5 0.0 1.6 1 0 0 1 1 1 0 Cation transport ATPase (P-type) RPA_interact_C PF14768.6 OQS03622.1 - 1.7e-12 47.8 5.1 1.7e-12 47.8 5.1 1.8 2 0 0 2 2 2 1 Replication protein A interacting C-terminal RPA_interact_N PF14766.6 OQS03622.1 - 0.00084 18.9 0.4 0.0017 18.0 0.4 1.4 1 0 0 1 1 1 1 Replication protein A interacting N-terminal UBM PF14377.6 OQS03622.1 - 0.045 13.2 2.6 0.11 12.0 1.0 2.2 1 1 1 2 2 2 0 Ubiquitin binding region DUF3666 PF12408.8 OQS03622.1 - 0.54 9.5 2.3 2 7.7 0.3 2.3 2 0 0 2 2 2 0 Ribose-5-phosphate isomerase tRNA-synt_2c PF01411.19 OQS03623.1 - 1.1e-207 691.0 0.0 1.4e-207 690.6 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (A) tRNA_SAD PF07973.14 OQS03623.1 - 2.3e-14 53.2 0.0 6.7e-14 51.7 0.0 1.8 2 0 0 2 2 2 1 Threonyl and Alanyl tRNA synthetase second additional domain DHHA1 PF02272.19 OQS03623.1 - 2.8e-09 37.5 10.8 5.5e-09 36.6 8.6 2.6 2 0 0 2 2 2 1 DHHA1 domain Pro_isomerase PF00160.21 OQS03624.1 - 3e-44 151.1 0.3 6.4e-44 150.0 0.0 1.7 2 0 0 2 2 2 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Chorein_N PF12624.7 OQS03624.1 - 0.0082 16.2 1.7 0.02 15.0 1.7 1.6 1 0 0 1 1 1 1 N-terminal region of Chorein or VPS13 Ntox50 PF15542.6 OQS03624.1 - 0.35 11.7 3.5 0.22 12.4 0.3 2.4 2 0 0 2 2 2 0 Bacterial toxin 50 Lambda_Bor PF06291.11 OQS03626.1 - 0.096 12.7 0.1 0.32 11.1 0.0 2.0 2 0 0 2 2 2 0 Bor protein Glyco_transf_8 PF01501.20 OQS03627.1 - 8.5e-05 22.2 1.3 0.00023 20.8 0.0 2.1 2 0 0 2 2 2 1 Glycosyl transferase family 8 Mannosyl_trans3 PF11051.8 OQS03627.1 - 0.033 13.5 0.0 0.071 12.5 0.0 1.5 2 0 0 2 2 2 0 Mannosyltransferase putative Amdase PF17645.1 OQS03628.1 - 0.099 12.3 0.2 4.8 6.7 0.0 2.3 2 0 0 2 2 2 0 Arylmalonate decarboxylase DUF1016_N PF17761.1 OQS03628.1 - 0.11 12.7 0.4 0.61 10.2 0.1 2.2 2 0 0 2 2 2 0 DUF1016 N-terminal domain FAA_hydrolase PF01557.18 OQS03629.1 - 1e-57 195.3 0.0 1.3e-57 195.0 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family FAA_hydrolase_N PF09298.11 OQS03629.1 - 2.9e-30 104.6 0.0 6.2e-30 103.5 0.0 1.5 2 0 0 2 2 2 1 Fumarylacetoacetase N-terminal Ank_4 PF13637.6 OQS03630.1 - 1.7e-13 50.8 0.4 9.8e-06 26.0 0.0 4.2 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 OQS03630.1 - 3.8e-10 39.8 0.6 0.0001 22.6 0.0 4.0 4 0 0 4 4 4 2 Ankyrin repeat Ank_2 PF12796.7 OQS03630.1 - 4e-10 40.1 0.5 1.3e-08 35.2 0.1 2.7 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OQS03630.1 - 4.9e-08 33.1 0.1 0.00012 22.3 0.0 3.0 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQS03630.1 - 1e-07 31.6 4.9 0.036 14.6 0.0 4.6 5 1 0 5 5 5 3 Ankyrin repeat DUF1016_N PF17761.1 OQS03631.1 - 0.076 13.2 0.0 0.19 11.9 0.0 1.6 1 0 0 1 1 1 0 DUF1016 N-terminal domain Mannosyl_trans3 PF11051.8 OQS03632.1 - 4.6e-10 39.3 0.0 1e-07 31.6 0.0 2.2 2 0 0 2 2 2 2 Mannosyltransferase putative Glyco_transf_8 PF01501.20 OQS03632.1 - 0.14 11.7 5.8 0.33 10.5 0.4 2.6 1 1 1 3 3 3 0 Glycosyl transferase family 8 Nucleotid_trans PF03407.16 OQS03632.1 - 1 9.3 3.7 19 5.1 0.4 2.4 2 1 0 2 2 2 0 Nucleotide-diphospho-sugar transferase CAP PF00188.26 OQS03633.1 - 1.1e-17 65.0 3.1 1.9e-17 64.2 3.1 1.4 1 0 0 1 1 1 1 Cysteine-rich secretory protein family Pex14_N PF04695.13 OQS03634.1 - 0.0025 18.5 0.0 0.0025 18.5 0.0 2.3 3 0 0 3 3 3 1 Peroxisomal membrane anchor protein (Pex14p) conserved region Ribosomal_L44 PF00935.19 OQS03635.1 - 3.9e-34 116.9 14.5 5.8e-34 116.4 14.5 1.3 1 0 0 1 1 1 1 Ribosomal protein L44 Zip PF02535.22 OQS03637.1 - 2e-27 96.3 6.3 6.2e-27 94.7 6.3 1.7 1 1 0 1 1 1 1 ZIP Zinc transporter SpoIIIAC PF06686.11 OQS03637.1 - 0.00062 19.9 0.4 0.00062 19.9 0.4 2.8 2 0 0 2 2 2 1 Stage III sporulation protein AC/AD protein family ThrE PF06738.12 OQS03637.1 - 0.014 14.8 0.4 0.014 14.8 0.4 2.7 3 0 0 3 3 3 0 Putative threonine/serine exporter Corona_M PF01635.18 OQS03637.1 - 0.083 12.2 0.3 15 4.8 0.1 2.6 3 0 0 3 3 3 0 Coronavirus M matrix/glycoprotein Mannosyl_trans3 PF11051.8 OQS03638.1 - 8e-13 48.4 0.3 7.7e-08 32.0 0.0 2.4 2 0 0 2 2 2 2 Mannosyltransferase putative Glyco_transf_8 PF01501.20 OQS03638.1 - 2.3e-07 30.6 1.2 1.8e-05 24.4 0.1 2.9 3 0 0 3 3 3 2 Glycosyl transferase family 8 GXWXG PF14231.6 OQS03640.1 - 0.089 12.9 0.0 4.6 7.4 0.1 2.2 2 0 0 2 2 2 0 GXWXG protein Spec3 PF15795.5 OQS03640.1 - 0.3 11.7 12.7 2.8 8.6 6.6 2.4 1 1 0 2 2 2 0 Ectodermal ciliogenesis protein SRF-TF PF00319.18 OQS03640.1 - 0.32 10.5 1.5 1.7 8.2 0.2 2.1 2 0 0 2 2 2 0 SRF-type transcription factor (DNA-binding and dimerisation domain) Na_Pi_cotrans PF02690.15 OQS03640.1 - 2.4 8.3 16.1 0.76 9.9 6.9 2.2 1 1 1 2 2 2 0 Na+/Pi-cotransporter MGC-24 PF05283.11 OQS03641.1 - 0.0092 16.4 7.1 0.013 16.0 7.1 1.2 1 0 0 1 1 1 1 Multi-glycosylated core protein 24 (MGC-24), sialomucin p25-alpha PF05517.12 OQS03642.1 - 0.015 15.5 0.0 4.9 7.3 0.0 2.5 2 0 0 2 2 2 0 p25-alpha AAA_8 PF12780.7 OQS03643.1 - 3.4e-17 62.6 0.0 1.4e-16 60.6 0.0 2.1 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 AAA_6 PF12774.7 OQS03643.1 - 5.1e-17 61.8 0.2 5.8e-16 58.4 0.2 2.7 1 1 0 1 1 1 1 Hydrolytic ATP binding site of dynein motor region MT PF12777.7 OQS03643.1 - 1.5e-14 53.8 5.8 1.5e-14 53.8 5.8 1.9 2 1 0 2 2 2 1 Microtubule-binding stalk of dynein motor AAA_7 PF12775.7 OQS03643.1 - 8.1e-14 51.5 0.3 2.3e-06 27.2 0.0 4.4 3 1 0 4 4 4 2 P-loop containing dynein motor region AAA_9 PF12781.7 OQS03643.1 - 7.7e-09 35.0 3.7 0.00022 20.4 0.6 2.8 2 0 0 2 2 2 2 ATP-binding dynein motor region Dynein_AAA_lid PF17852.1 OQS03643.1 - 1.4e-05 25.2 1.5 7.2e-05 22.9 0.1 3.0 3 0 0 3 3 3 1 Dynein heavy chain AAA lid domain AAA_29 PF13555.6 OQS03643.1 - 0.00073 19.2 0.1 3.5 7.5 0.0 3.2 3 0 0 3 3 3 2 P-loop containing region of AAA domain AAA_lid_11 PF18198.1 OQS03643.1 - 0.0013 18.6 0.2 0.006 16.4 0.2 2.2 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain RsgA_GTPase PF03193.16 OQS03643.1 - 0.0017 18.3 1.1 2.4 8.0 0.0 4.4 4 0 0 4 4 4 1 RsgA GTPase AAA_16 PF13191.6 OQS03643.1 - 0.0022 18.4 0.1 8.9 6.7 0.0 4.4 3 0 0 3 3 3 1 AAA ATPase domain AAA_18 PF13238.6 OQS03643.1 - 0.0024 18.4 0.2 2.6 8.6 0.0 4.0 3 0 0 3 3 3 1 AAA domain RNA_helicase PF00910.22 OQS03643.1 - 0.0081 16.5 0.2 52 4.3 0.0 4.7 4 0 0 4 4 4 0 RNA helicase AAA_lid_1 PF17857.1 OQS03643.1 - 0.098 12.9 0.8 0.38 11.0 0.0 2.5 2 0 0 2 2 1 0 AAA+ lid domain AAA_5 PF07728.14 OQS03643.1 - 0.11 12.5 0.3 56 3.7 0.0 4.1 4 0 0 4 4 4 0 AAA domain (dynein-related subfamily) AAA_28 PF13521.6 OQS03643.1 - 0.24 11.6 1.2 24 5.1 0.0 3.5 4 0 0 4 4 3 0 AAA domain AAA PF00004.29 OQS03643.1 - 2.5 8.5 8.4 16 5.9 0.0 5.2 6 0 0 6 6 5 0 ATPase family associated with various cellular activities (AAA) MnmE_helical PF12631.7 OQS03643.1 - 2.6 8.2 6.3 0.96 9.6 0.0 3.0 3 0 0 3 3 3 0 MnmE helical domain DUF1492 PF07374.11 OQS03643.1 - 4.1 7.6 7.5 0.37 11.0 0.4 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1492) AAA_22 PF13401.6 OQS03643.1 - 5.5 7.3 14.3 1.7 8.9 0.0 6.1 7 0 0 7 7 6 0 AAA domain AAA_23 PF13476.6 OQS03643.1 - 9.2 6.7 14.8 9.3 6.7 0.0 4.8 5 0 0 5 5 5 0 AAA domain Peptidase_C1 PF00112.23 OQS03644.1 - 0.067 13.3 0.0 0.15 12.2 0.0 1.5 1 1 1 2 2 2 0 Papain family cysteine protease 2-oxoacid_dh PF00198.23 OQS03645.1 - 2.9e-53 180.7 0.0 4.3e-53 180.1 0.0 1.3 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 OQS03645.1 - 1.4e-17 63.3 0.3 2.8e-17 62.3 0.3 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.17 OQS03645.1 - 9.2e-14 51.5 0.8 2.4e-13 50.2 0.8 1.8 1 0 0 1 1 1 1 e3 binding domain Biotin_lipoyl_2 PF13533.6 OQS03645.1 - 0.0032 17.2 0.0 0.012 15.4 0.0 2.0 1 0 0 1 1 1 1 Biotin-lipoyl like Chalcone_3 PF16036.5 OQS03645.1 - 0.014 15.5 0.2 0.031 14.4 0.2 1.6 1 0 0 1 1 1 0 Chalcone isomerase-like LPP PF04728.13 OQS03645.1 - 0.027 14.9 5.2 8.5 6.9 0.3 3.7 3 0 0 3 3 3 0 Lipoprotein leucine-zipper DUF2443 PF10398.9 OQS03645.1 - 0.22 11.6 3.1 7.6 6.7 0.1 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2443) DivIC PF04977.15 OQS03645.1 - 1.3 8.9 6.9 11 5.9 0.9 3.0 3 0 0 3 3 3 0 Septum formation initiator Peptidase_C1 PF00112.23 OQS03647.1 - 5.8e-07 29.8 1.2 7.7e-05 22.9 1.2 2.7 1 1 0 1 1 1 1 Papain family cysteine protease DUF3617 PF12276.8 OQS03647.1 - 0.053 13.8 2.1 0.097 13.0 2.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3617) NO_synthase PF02898.15 OQS03651.1 - 2.2e-132 441.5 0.0 3.4e-132 440.9 0.0 1.2 1 0 0 1 1 1 1 Nitric oxide synthase, oxygenase domain DUF2431 PF10354.9 OQS03651.1 - 1.8e-50 171.5 0.0 4.6e-50 170.2 0.0 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF2431) Flavodoxin_1 PF00258.25 OQS03651.1 - 1.6e-21 77.0 0.0 3.3e-21 76.0 0.0 1.6 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.21 OQS03651.1 - 4e-17 62.8 0.0 3.1e-10 40.7 0.0 3.9 3 1 0 3 3 3 2 Oxidoreductase NAD-binding domain FAD_binding_1 PF00667.20 OQS03651.1 - 8.1e-17 61.5 0.0 1.6e-16 60.6 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain zf-C2H2_jaz PF12171.8 OQS03651.1 - 0.039 14.2 0.7 0.083 13.2 0.7 1.6 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding Flavodoxin_5 PF12724.7 OQS03651.1 - 0.097 12.9 0.2 0.28 11.4 0.0 1.9 2 0 0 2 2 2 0 Flavodoxin domain zf-met PF12874.7 OQS03651.1 - 0.16 12.4 0.9 0.4 11.1 0.9 1.8 1 0 0 1 1 1 0 Zinc-finger of C2H2 type DUF962 PF06127.11 OQS03652.1 - 1.3e-23 82.8 0.1 4.6e-23 81.1 0.1 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF962) Pyrophosphatase PF00719.19 OQS03653.1 - 8.7e-48 162.1 0.2 1.4e-47 161.5 0.2 1.3 1 0 0 1 1 1 1 Inorganic pyrophosphatase WD40 PF00400.32 OQS03653.1 - 1.1e-22 79.9 24.6 0.00038 21.2 0.0 10.6 9 3 3 12 12 12 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OQS03653.1 - 1.2e-17 64.0 0.9 9.1e-05 22.7 0.0 6.1 4 4 4 8 8 8 4 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 OQS03653.1 - 5.9e-08 32.4 0.0 0.23 10.7 0.0 4.9 3 1 2 5 5 5 2 WD40-like domain PQQ_2 PF13360.6 OQS03653.1 - 3.5e-06 26.8 0.8 0.0028 17.3 0.1 3.4 3 0 0 3 3 3 1 PQQ-like domain SGL PF08450.12 OQS03653.1 - 0.00028 20.6 0.6 0.18 11.4 0.0 3.2 3 0 0 3 3 3 2 SMP-30/Gluconolactonase/LRE-like region PQQ_3 PF13570.6 OQS03653.1 - 0.00086 19.7 10.1 2.9 8.5 0.2 6.1 7 0 0 7 7 7 1 PQQ-like domain Hira PF07569.11 OQS03653.1 - 0.0018 18.0 0.3 0.47 10.1 0.0 3.0 3 0 0 3 3 3 1 TUP1-like enhancer of split Cytochrom_D1 PF02239.16 OQS03653.1 - 0.0018 16.9 0.6 1.4 7.3 0.0 3.2 4 0 0 4 4 4 2 Cytochrome D1 heme domain Nup160 PF11715.8 OQS03653.1 - 0.0072 15.0 1.1 7.1 5.1 0.0 3.1 2 1 1 3 3 3 2 Nucleoporin Nup120/160 HPS3_N PF14761.6 OQS03653.1 - 0.019 14.5 0.0 0.68 9.4 0.0 2.7 2 1 1 3 3 3 0 Hermansky-Pudlak syndrome 3 Ge1_WD40 PF16529.5 OQS03653.1 - 0.045 12.7 0.1 22 3.9 0.0 3.2 3 0 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein PQQ PF01011.21 OQS03653.1 - 3.5 7.7 8.2 1.7 8.7 1.4 3.6 3 0 0 3 3 3 0 PQQ enzyme repeat ABC2_membrane PF01061.24 OQS03654.1 - 2.5e-67 226.3 51.6 1.4e-38 132.4 21.3 3.1 4 0 0 4 4 3 2 ABC-2 type transporter ABC_tran PF00005.27 OQS03654.1 - 1.1e-34 119.8 0.0 5.2e-18 65.9 0.0 2.3 2 0 0 2 2 2 2 ABC transporter ABC2_membrane_3 PF12698.7 OQS03654.1 - 8.3e-08 31.7 42.6 1e-06 28.2 11.9 2.6 2 1 0 2 2 2 2 ABC-2 family transporter protein AAA_29 PF13555.6 OQS03654.1 - 7e-07 28.9 1.3 0.0089 15.8 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 OQS03654.1 - 2.3e-05 24.4 0.1 0.0012 18.8 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase AAA_23 PF13476.6 OQS03654.1 - 3.1e-05 24.6 0.4 0.025 15.1 0.1 2.4 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.6 OQS03654.1 - 5.1e-05 23.2 2.9 0.44 10.3 0.1 3.4 2 1 1 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_25 PF13481.6 OQS03654.1 - 8.6e-05 22.2 0.2 0.33 10.5 0.0 2.7 3 0 0 3 3 3 2 AAA domain AAA_22 PF13401.6 OQS03654.1 - 0.00034 20.9 0.3 1.3 9.3 0.0 2.7 2 0 0 2 2 2 2 AAA domain SMC_N PF02463.19 OQS03654.1 - 0.00045 19.7 0.0 0.4 10.1 0.0 3.2 3 0 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA PF00004.29 OQS03654.1 - 0.0022 18.4 0.9 0.91 10.0 0.0 3.1 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 OQS03654.1 - 0.0027 18.1 0.1 2.7 8.4 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain AAA_18 PF13238.6 OQS03654.1 - 0.0029 18.2 0.0 3.1 8.4 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 OQS03654.1 - 0.0038 17.0 3.4 1 9.0 0.7 2.4 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.6 OQS03654.1 - 0.0045 17.1 0.0 4 7.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 OQS03654.1 - 0.011 15.6 2.1 1.2 9.1 0.0 2.5 2 0 0 2 2 2 0 NACHT domain PDR_CDR PF06422.12 OQS03654.1 - 0.039 13.9 0.3 0.039 13.9 0.3 3.7 3 0 0 3 3 3 0 CDR ABC transporter cobW PF02492.19 OQS03654.1 - 0.039 13.5 1.9 2.3 7.8 0.3 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain PDR_assoc PF08370.11 OQS03654.1 - 0.056 13.2 1.2 4.2 7.2 0.1 3.0 2 0 0 2 2 2 0 Plant PDR ABC transporter associated TsaE PF02367.17 OQS03654.1 - 0.058 13.4 1.8 0.9 9.6 0.2 2.9 3 0 0 3 3 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Zeta_toxin PF06414.12 OQS03654.1 - 0.082 12.2 1.6 5.8 6.1 0.2 2.3 2 0 0 2 2 2 0 Zeta toxin MMR_HSR1 PF01926.23 OQS03654.1 - 0.096 12.8 1.4 5.1 7.2 0.1 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase NTPase_1 PF03266.15 OQS03654.1 - 0.21 11.5 3.8 0.76 9.7 0.0 2.7 3 0 0 3 3 3 0 NTPase DUF87 PF01935.17 OQS03654.1 - 0.27 11.3 3.5 2.7 8.0 0.4 2.3 2 0 0 2 2 2 0 Helicase HerA, central domain AAA_19 PF13245.6 OQS03654.1 - 0.4 11.0 4.5 1.9 8.8 0.2 2.5 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 OQS03654.1 - 0.53 9.8 1.8 25 4.3 0.1 2.7 3 0 0 3 3 3 0 P-loop containing dynein motor region AAA_24 PF13479.6 OQS03654.1 - 1 9.1 2.6 23 4.6 0.0 2.4 2 0 0 2 2 2 0 AAA domain Acyltransferase PF01553.21 OQS03655.1 - 2.4e-15 56.3 0.0 1.5e-07 31.1 0.0 2.4 2 0 0 2 2 2 2 Acyltransferase eIF2A PF08662.11 OQS03656.1 - 2e-55 187.7 7.1 8.5e-49 166.1 1.4 3.8 2 1 1 4 4 4 3 Eukaryotic translation initiation factor eIF2A IKI3 PF04762.12 OQS03656.1 - 1.1e-07 30.3 0.1 3.2e-07 28.8 0.1 1.7 2 0 0 2 2 2 1 IKI3 family ANAPC4_WD40 PF12894.7 OQS03656.1 - 6.2e-05 23.2 0.2 7.7 6.9 0.0 5.7 2 2 5 7 7 7 1 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 OQS03656.1 - 0.00021 22.0 0.3 3.9 8.5 0.0 5.2 4 1 1 5 5 5 1 WD domain, G-beta repeat RRM_1 PF00076.22 OQS03656.1 - 0.00041 20.1 0.0 0.0077 16.0 0.0 2.4 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ABC_tran_Xtn PF12848.7 OQS03656.1 - 0.22 11.6 7.3 0.48 10.5 7.3 1.5 1 0 0 1 1 1 0 ABC transporter TFIIIC_delta PF12657.7 OQS03656.1 - 0.62 10.0 2.5 7.7 6.4 0.0 3.3 3 1 0 3 3 3 0 Transcription factor IIIC subunit delta N-term Pex2_Pex12 PF04757.14 OQS03657.1 - 2.6e-19 69.7 1.4 4.2e-19 69.0 1.4 1.3 1 1 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_3 PF13920.6 OQS03657.1 - 2.8e-09 36.7 11.2 4.6e-09 36.0 11.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 OQS03657.1 - 1.2e-08 35.2 15.2 2e-08 34.4 15.2 1.4 1 0 0 1 1 1 1 Ring finger domain Prok-RING_4 PF14447.6 OQS03657.1 - 3.5e-08 33.2 11.9 5.9e-08 32.5 11.9 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 OQS03657.1 - 4.1e-08 32.9 14.2 7.7e-08 32.1 14.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 OQS03657.1 - 1.8e-07 30.9 13.3 3.1e-07 30.1 13.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OQS03657.1 - 1.6e-05 24.7 11.3 3e-05 23.9 11.3 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 OQS03657.1 - 5.7e-05 23.0 14.3 0.00017 21.5 14.3 1.8 1 1 0 1 1 1 1 RING-type zinc-finger zf-rbx1 PF12678.7 OQS03657.1 - 0.00024 21.3 10.9 0.00048 20.4 10.9 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_4 PF15227.6 OQS03657.1 - 0.0034 17.5 10.5 0.0034 17.5 10.5 1.7 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-ANAPC11 PF12861.7 OQS03657.1 - 0.0097 15.9 3.2 0.021 14.9 2.7 1.9 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger DUF3540 PF12059.8 OQS03657.1 - 0.13 12.1 0.0 0.2 11.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3540) zf-RING_6 PF14835.6 OQS03657.1 - 0.69 9.8 6.8 1.4 8.9 6.8 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_10 PF16685.5 OQS03657.1 - 0.95 9.6 12.1 1.4 9.1 10.9 1.8 2 0 0 2 2 2 0 zinc RING finger of MSL2 Sas10_Utp3 PF04000.15 OQS03658.1 - 1.5e-09 38.3 0.7 1.5e-09 38.3 0.7 1.9 2 0 0 2 2 2 1 Sas10/Utp3/C1D family TetR_C_30 PF17939.1 OQS03658.1 - 0.0086 16.3 0.0 0.013 15.7 0.0 1.3 1 0 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain Peptidase_S30 PF01577.16 OQS03658.1 - 0.54 9.8 10.6 0.73 9.4 10.5 1.3 1 1 0 1 1 1 0 Potyvirus P1 protease AP3D1 PF06375.11 OQS03658.1 - 0.95 9.7 13.4 0.98 9.6 12.6 1.4 1 1 0 1 1 1 0 AP-3 complex subunit delta-1 Metallophos PF00149.28 OQS03659.1 - 3.1e-37 129.1 0.1 4e-37 128.7 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 OQS03659.1 - 3e-16 59.6 1.0 7.4e-16 58.3 1.0 1.7 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain HscB_4_cys PF18256.1 OQS03659.1 - 9.2 6.2 7.5 9.5 6.1 0.3 3.0 3 0 0 3 3 3 0 Co-chaperone HscB tetracysteine metal binding motif Epimerase PF01370.21 OQS03662.1 - 4.1e-30 105.0 0.0 5.2e-30 104.7 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 OQS03662.1 - 1.9e-26 92.8 0.2 5.4e-18 65.1 0.1 2.1 1 1 1 2 2 2 2 Male sterility protein 3Beta_HSD PF01073.19 OQS03662.1 - 1.5e-21 76.6 0.0 2e-21 76.2 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 OQS03662.1 - 6.9e-20 71.7 0.1 8.9e-20 71.3 0.1 1.2 1 0 0 1 1 1 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 OQS03662.1 - 6.4e-16 58.7 0.0 1.9e-15 57.1 0.0 1.7 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 OQS03662.1 - 1.8e-11 43.7 0.0 2.6e-11 43.2 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain NmrA PF05368.13 OQS03662.1 - 8e-11 41.9 0.1 1.3e-10 41.2 0.1 1.3 1 0 0 1 1 1 1 NmrA-like family Polysacc_synt_2 PF02719.15 OQS03662.1 - 1.7e-10 40.6 0.1 3.1e-10 39.7 0.1 1.4 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein adh_short PF00106.25 OQS03662.1 - 1.4e-05 24.7 0.1 3.1e-05 23.5 0.1 1.6 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OQS03662.1 - 2.4e-05 24.3 0.1 4.7e-05 23.4 0.1 1.4 1 0 0 1 1 1 1 KR domain TrkA_N PF02254.18 OQS03662.1 - 5.4e-05 23.4 0.1 0.0001 22.5 0.1 1.5 1 0 0 1 1 1 1 TrkA-N domain Sacchrp_dh_NADP PF03435.18 OQS03662.1 - 0.0011 19.2 0.0 0.0023 18.2 0.0 1.6 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_2 PF03446.15 OQS03662.1 - 0.036 14.2 0.0 0.056 13.6 0.0 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase ADH_zinc_N PF00107.26 OQS03662.1 - 0.12 12.4 0.0 0.23 11.4 0.0 1.4 1 0 0 1 1 1 0 Zinc-binding dehydrogenase Inh PF02974.14 OQS03663.1 - 0.042 13.9 0.1 0.089 12.9 0.1 1.5 1 0 0 1 1 1 0 Protease inhibitor Inh Epimerase PF01370.21 OQS03664.1 - 4.2e-32 111.5 0.0 5.4e-32 111.2 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 OQS03664.1 - 3.9e-24 85.2 0.0 5.7e-18 65.0 0.0 2.1 1 1 1 2 2 2 2 Male sterility protein 3Beta_HSD PF01073.19 OQS03664.1 - 2.5e-18 66.1 0.0 3.3e-18 65.7 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 OQS03664.1 - 6.3e-18 65.3 0.0 8.4e-18 64.9 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 OQS03664.1 - 1.1e-16 61.1 0.0 2.9e-16 59.8 0.0 1.7 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 OQS03664.1 - 4.8e-11 42.3 0.0 6.8e-11 41.8 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain NmrA PF05368.13 OQS03664.1 - 1.6e-10 40.9 0.1 3.5e-10 39.8 0.1 1.5 1 1 0 1 1 1 1 NmrA-like family Polysacc_synt_2 PF02719.15 OQS03664.1 - 1.4e-08 34.2 0.0 3.5e-08 32.9 0.0 1.6 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein adh_short PF00106.25 OQS03664.1 - 7e-05 22.4 0.1 0.00013 21.4 0.1 1.5 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OQS03664.1 - 0.0003 20.8 0.2 0.00083 19.3 0.2 1.7 1 1 0 1 1 1 1 KR domain TrkA_N PF02254.18 OQS03664.1 - 0.011 15.9 0.0 0.026 14.8 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain NAD_binding_2 PF03446.15 OQS03664.1 - 0.069 13.3 0.0 0.11 12.6 0.0 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase TMIE PF16038.5 OQS03664.1 - 0.099 12.5 0.0 0.21 11.5 0.0 1.5 1 0 0 1 1 1 0 TMIE protein p450 PF00067.22 OQS03666.1 - 1.3e-14 53.9 0.3 2.4e-13 49.6 0.3 2.2 1 1 0 1 1 1 1 Cytochrome P450 Lipoxygenase PF00305.19 OQS03666.1 - 3.2e-13 49.0 3.0 1e-12 47.3 3.0 1.8 1 1 0 1 1 1 1 Lipoxygenase Lipoxygenase PF00305.19 OQS03667.1 - 5.7e-12 44.9 1.2 3.2e-11 42.4 0.2 2.2 2 1 0 2 2 2 1 Lipoxygenase RNA_pol_Rpb5_C PF01191.19 OQS03667.1 - 0.16 11.9 0.0 5.9 6.8 0.0 2.4 2 0 0 2 2 2 0 RNA polymerase Rpb5, C-terminal domain DUF4203 PF13886.6 OQS03668.1 - 1.1e-41 142.7 32.5 1.4e-41 142.4 32.5 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4203) Pkinase PF00069.25 OQS03669.1 - 6.5e-87 291.2 1.6 6.5e-33 114.2 0.0 4.1 3 1 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 OQS03669.1 - 2.7e-86 289.1 5.4 2.6e-32 112.1 0.0 4.2 3 1 1 4 4 4 4 Protein tyrosine kinase Myb_DNA-bind_6 PF13921.6 OQS03669.1 - 2.2e-24 85.5 16.4 1.4e-10 41.2 0.9 5.2 1 1 3 4 4 4 3 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 OQS03669.1 - 2.1e-19 69.4 26.7 1.1e-06 28.7 0.1 7.1 6 2 1 7 7 7 4 Myb-like DNA-binding domain Kinase-like PF14531.6 OQS03669.1 - 2.2e-07 30.5 0.0 4.2e-05 23.0 0.0 2.4 2 0 0 2 2 2 2 Kinase-like Myb_DNA-bind_4 PF13837.6 OQS03669.1 - 0.016 15.5 8.2 1.2 9.6 0.9 4.0 2 1 1 3 3 3 0 Myb/SANT-like DNA-binding domain Kdo PF06293.14 OQS03669.1 - 0.035 13.4 5.2 2.1 7.7 0.8 3.0 3 0 0 3 3 3 0 Lipopolysaccharide kinase (Kdo/WaaP) family COPI_assoc PF08507.10 OQS03670.1 - 3.3e-10 40.1 11.7 4e-10 39.8 11.7 1.1 1 0 0 1 1 1 1 COPI associated protein Comm PF15957.5 OQS03670.1 - 0.47 10.8 2.2 0.75 10.1 0.1 2.1 2 0 0 2 2 2 0 Commissureless TB2_DP1_HVA22 PF03134.19 OQS03671.1 - 2.7e-16 59.2 2.6 5.2e-16 58.3 2.6 1.5 1 0 0 1 1 1 1 TB2/DP1, HVA22 family DUF2157 PF09925.9 OQS03671.1 - 0.049 13.4 1.5 0.071 12.9 1.5 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2157) LicD PF04991.13 OQS03672.1 - 2.3e-06 27.9 0.0 2.3e-06 27.9 0.0 1.3 1 1 0 1 1 1 1 LicD family Cdc13_OB4_dimer PF18233.1 OQS03672.1 - 0.13 12.4 0.4 0.86 9.8 0.0 2.0 2 0 0 2 2 2 0 Cdc13 OB4 dimerization domain FYVE PF01363.21 OQS03673.1 - 8.7e-16 57.8 10.9 1.7e-15 56.9 10.9 1.5 1 0 0 1 1 1 1 FYVE zinc finger zf-piccolo PF05715.13 OQS03673.1 - 1.5 9.1 8.5 3.6 7.8 8.5 1.7 1 0 0 1 1 1 0 Piccolo Zn-finger FYVE_2 PF02318.16 OQS03673.1 - 3.7 7.8 23.4 0.035 14.3 9.6 2.6 2 0 0 2 2 2 0 FYVE-type zinc finger GRDP-like PF07173.12 OQS03674.1 - 1.9e-14 54.5 0.4 1.9e-14 54.5 0.4 2.1 2 0 0 2 2 2 1 Glycine-rich domain-containing protein-like PH PF00169.29 OQS03674.1 - 2.3e-06 28.0 1.7 1.5e-05 25.5 0.2 2.5 2 0 0 2 2 2 1 PH domain Elicitin PF00964.17 OQS03675.1 - 0.0034 17.4 1.4 0.0061 16.6 1.4 1.4 1 0 0 1 1 1 1 Elicitin ABC_tran PF00005.27 OQS03676.1 - 6.2e-30 104.5 0.0 1.2e-29 103.6 0.0 1.5 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.23 OQS03676.1 - 6.2e-25 88.4 10.8 1.2e-24 87.4 10.8 1.5 1 0 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.19 OQS03676.1 - 1.1e-08 34.9 1.7 3.8e-07 29.8 1.7 2.2 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 OQS03676.1 - 3.1e-05 23.9 0.1 0.00014 21.8 0.0 2.1 2 0 0 2 2 2 1 RsgA GTPase AAA_29 PF13555.6 OQS03676.1 - 0.0023 17.6 0.0 0.0064 16.2 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.6 OQS03676.1 - 0.0042 17.5 0.0 0.009 16.4 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_15 PF13175.6 OQS03676.1 - 0.0063 16.3 0.0 0.012 15.3 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 OQS03676.1 - 0.0088 16.3 0.7 0.13 12.5 0.7 2.5 1 1 0 1 1 1 1 AAA domain AAA_21 PF13304.6 OQS03676.1 - 0.024 14.5 0.1 0.26 11.1 0.0 2.3 1 1 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA PF00004.29 OQS03676.1 - 0.025 15.0 1.3 0.56 10.6 1.3 2.6 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_23 PF13476.6 OQS03676.1 - 0.031 14.8 0.0 0.076 13.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain SbcCD_C PF13558.6 OQS03676.1 - 0.056 13.7 0.1 0.18 12.1 0.1 1.9 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit Ku_PK_bind PF08785.11 OQS03676.1 - 0.28 11.3 3.3 7.3 6.8 0.0 3.6 4 0 0 4 4 4 0 Ku C terminal domain like ABC_membrane_2 PF06472.15 OQS03676.1 - 0.84 9.0 5.7 0.11 11.9 0.9 2.0 2 1 0 2 2 2 0 ABC transporter transmembrane region 2 Atx10homo_assoc PF09759.9 OQS03677.1 - 0.034 14.2 0.1 0.067 13.2 0.1 1.5 1 0 0 1 1 1 0 Spinocerebellar ataxia type 10 protein domain PUF PF00806.19 OQS03678.1 - 6e-12 44.6 0.7 0.034 13.9 0.0 7.4 8 0 0 8 8 8 3 Pumilio-family RNA binding repeat DUF3916 PF13079.6 OQS03678.1 - 0.029 14.2 0.0 0.15 11.9 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3916) NPA PF16469.5 OQS03678.1 - 0.05 14.2 1.5 0.22 12.1 1.5 2.1 1 0 0 1 1 1 0 Nematode polyprotein allergen ABA-1 Pkinase_Tyr PF07714.17 OQS03679.1 - 1.2e-08 34.6 1.5 1.2e-08 34.5 1.5 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OQS03679.1 - 4.5e-07 29.5 0.9 4.5e-07 29.5 0.9 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQS03680.1 - 2.1e-13 50.2 0.0 2.9e-13 49.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OQS03680.1 - 2.8e-13 49.8 0.0 4.4e-13 49.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Ribosomal_S7 PF00177.21 OQS03680.1 - 0.072 12.7 0.0 0.097 12.3 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein S7p/S5e DHO_dh PF01180.21 OQS03681.1 - 1.7e-107 359.0 0.0 2e-107 358.8 0.0 1.0 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase NMO PF03060.15 OQS03681.1 - 0.027 13.9 0.1 0.046 13.1 0.1 1.3 1 0 0 1 1 1 0 Nitronate monooxygenase FMN_dh PF01070.18 OQS03681.1 - 0.17 10.9 0.5 0.58 9.1 0.5 1.7 1 1 0 1 1 1 0 FMN-dependent dehydrogenase Metallophos PF00149.28 OQS03682.1 - 8.7e-16 59.0 0.9 1.6e-15 58.2 0.9 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Pur_ac_phosph_N PF16656.5 OQS03682.1 - 2e-07 31.5 0.8 2e-07 31.5 0.8 1.9 2 0 0 2 2 2 1 Purple acid Phosphatase, N-terminal domain Metallophos_C PF14008.6 OQS03682.1 - 0.00071 20.4 0.3 0.0031 18.4 0.0 2.2 2 0 0 2 2 2 1 Iron/zinc purple acid phosphatase-like protein C Citrate_synt PF00285.21 OQS03682.1 - 0.16 11.0 0.0 0.25 10.4 0.0 1.2 1 0 0 1 1 1 0 Citrate synthase, C-terminal domain TMEM51 PF15345.6 OQS03683.1 - 0.0012 18.7 2.6 0.002 18.0 0.0 2.2 1 1 1 2 2 2 1 Transmembrane protein 51 TctB PF07331.11 OQS03683.1 - 0.13 12.6 0.0 0.3 11.4 0.0 1.6 1 0 0 1 1 1 0 Tripartite tricarboxylate transporter TctB family ECH_1 PF00378.20 OQS03685.1 - 7e-51 172.9 0.0 8e-51 172.8 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 OQS03685.1 - 3.6e-16 59.6 0.0 4.1e-16 59.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase TPD PF14811.6 OQS03686.1 - 1.1e-33 116.0 0.0 2.7e-33 114.7 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function TPD sequence-motif SET PF00856.28 OQS03686.1 - 8.7e-13 49.0 0.0 1.8e-12 47.9 0.0 1.6 1 0 0 1 1 1 1 SET domain zf-MYND PF01753.18 OQS03686.1 - 7.7e-11 41.9 15.7 7.7e-11 41.9 15.7 2.5 2 0 0 2 2 2 1 MYND finger TPR_12 PF13424.6 OQS03686.1 - 0.00036 20.8 2.6 0.0025 18.1 0.9 2.6 1 1 1 2 2 2 2 Tetratricopeptide repeat zf-PARP PF00645.18 OQS03687.1 - 1.1e-07 32.6 0.5 4.1e-07 30.8 0.5 1.7 1 1 0 1 1 1 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region DUF2235 PF09994.9 OQS03688.1 - 1.3e-146 487.4 3.9 3.1e-52 177.7 0.0 6.0 6 0 0 6 6 6 5 Uncharacterized alpha/beta hydrolase domain (DUF2235) TPR_1 PF00515.28 OQS03688.1 - 6.3e-14 51.1 1.6 5e-05 22.9 0.0 5.0 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_2 PF07719.17 OQS03688.1 - 7.9e-13 47.5 3.4 0.0026 17.8 0.0 5.1 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_8 PF13181.6 OQS03688.1 - 3.9e-07 29.8 0.1 0.028 14.6 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat CS PF04969.16 OQS03688.1 - 1.5e-05 25.9 0.6 4.4e-05 24.4 0.6 1.9 1 0 0 1 1 1 1 CS domain TPR_14 PF13428.6 OQS03688.1 - 0.0012 19.5 2.1 1.7 9.7 0.1 4.6 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.6 OQS03688.1 - 0.0034 17.6 4.2 5.9 7.3 0.1 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_11 PF13414.6 OQS03688.1 - 0.01 15.5 2.9 6.5 6.5 0.1 3.7 4 0 0 4 4 4 0 TPR repeat Dimerisation PF08100.11 OQS03688.1 - 0.03 14.3 0.0 0.23 11.5 0.0 2.5 2 0 0 2 2 2 0 Dimerisation domain TPR_9 PF13371.6 OQS03688.1 - 0.033 14.3 0.4 1.6 8.9 0.1 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat Neural_ProG_Cyt PF06567.11 OQS03688.1 - 0.039 14.2 2.1 0.096 12.9 0.3 2.5 2 0 0 2 2 2 0 Neural chondroitin sulphate proteoglycan cytoplasmic domain TPR_6 PF13174.6 OQS03688.1 - 0.089 13.5 1.3 4.1 8.2 0.2 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat SAGA-Tad1 PF12767.7 OQS03688.1 - 0.19 11.4 4.5 0.57 9.9 3.4 2.2 2 0 0 2 2 2 0 Transcriptional regulator of RNA polII, SAGA, subunit TPR_16 PF13432.6 OQS03688.1 - 2.1 9.1 8.1 20 5.9 0.1 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat PRA1 PF03208.19 OQS03689.1 - 1e-17 64.1 10.9 1.3e-17 63.8 10.9 1.1 1 0 0 1 1 1 1 PRA1 family protein R3H PF01424.22 OQS03692.1 - 2.4e-16 59.4 0.0 4.3e-16 58.6 0.0 1.5 1 0 0 1 1 1 1 R3H domain SUZ PF12752.7 OQS03692.1 - 4e-10 40.3 3.1 4e-10 40.3 3.1 2.3 1 1 1 2 2 2 1 SUZ domain DUF2981 PF11200.8 OQS03692.1 - 1.8 8.2 3.6 2.7 7.7 3.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2981) PLU-1 PF08429.11 OQS03693.1 - 2.1e-42 145.6 40.9 3.2e-18 66.0 5.3 5.7 4 1 1 5 5 5 5 PLU-1-like protein AAA PF00004.29 OQS03693.1 - 1.5e-35 122.5 0.1 1.3e-34 119.5 0.0 2.7 3 0 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 OQS03693.1 - 2.6e-12 46.3 0.3 1e-11 44.4 0.0 2.3 2 0 0 2 2 1 1 AAA+ lid domain PHD PF00628.29 OQS03693.1 - 1.5e-09 37.6 5.5 4.1e-09 36.2 5.5 1.7 1 0 0 1 1 1 1 PHD-finger AAA_33 PF13671.6 OQS03693.1 - 0.0018 18.5 0.5 0.014 15.6 0.0 2.9 3 0 0 3 3 2 1 AAA domain AAA_16 PF13191.6 OQS03693.1 - 0.002 18.5 2.4 0.015 15.7 0.1 3.5 3 1 1 4 4 3 1 AAA ATPase domain AAA_24 PF13479.6 OQS03693.1 - 0.0036 17.0 0.0 0.011 15.5 0.0 1.8 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.12 OQS03693.1 - 0.0043 16.8 0.0 0.012 15.4 0.0 1.7 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 OQS03693.1 - 0.0047 17.5 0.0 0.024 15.2 0.0 2.3 1 0 0 1 1 1 1 AAA domain Bac_DnaA PF00308.18 OQS03693.1 - 0.0051 16.7 0.1 0.15 11.8 0.0 2.7 2 0 0 2 2 2 1 Bacterial dnaA protein AAA_5 PF07728.14 OQS03693.1 - 0.0055 16.7 0.1 0.058 13.4 0.1 2.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 OQS03693.1 - 0.0063 16.8 0.8 0.14 12.5 0.1 3.3 2 1 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 OQS03693.1 - 0.011 15.5 0.2 0.13 12.0 0.0 2.5 2 0 0 2 2 2 0 IstB-like ATP binding protein DUF815 PF05673.13 OQS03693.1 - 0.014 14.5 0.0 0.039 13.1 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Pox_P35 PF03213.14 OQS03693.1 - 0.016 14.4 0.0 0.043 13.0 0.0 1.7 1 0 0 1 1 1 0 Poxvirus P35 protein Parvo_NS1 PF01057.17 OQS03693.1 - 0.017 14.3 0.0 0.041 13.0 0.0 1.6 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Mg_chelatase PF01078.21 OQS03693.1 - 0.026 13.9 0.1 0.1 12.0 0.1 2.0 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Zeta_toxin PF06414.12 OQS03693.1 - 0.032 13.5 0.2 2.2 7.5 0.0 2.8 2 0 0 2 2 2 0 Zeta toxin TIP49 PF06068.13 OQS03693.1 - 0.033 13.4 1.3 0.044 13.0 0.1 1.8 2 0 0 2 2 1 0 TIP49 P-loop domain TsaE PF02367.17 OQS03693.1 - 0.051 13.6 0.0 0.27 11.2 0.0 2.2 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_2 PF07724.14 OQS03693.1 - 0.068 13.3 0.0 0.21 11.7 0.0 1.8 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) NACHT PF05729.12 OQS03693.1 - 0.069 13.1 0.2 0.21 11.5 0.2 1.8 1 0 0 1 1 1 0 NACHT domain RNA_helicase PF00910.22 OQS03693.1 - 0.081 13.3 0.2 0.51 10.8 0.1 2.5 2 0 0 2 2 2 0 RNA helicase Sigma54_activat PF00158.26 OQS03693.1 - 0.093 12.4 0.0 0.21 11.3 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_7 PF12775.7 OQS03693.1 - 0.15 11.6 0.3 0.46 10.0 0.0 2.0 2 0 0 2 2 1 0 P-loop containing dynein motor region AAA_14 PF13173.6 OQS03693.1 - 0.15 12.1 0.0 0.56 10.2 0.0 2.0 1 0 0 1 1 1 0 AAA domain ELM2 PF01448.24 OQS03693.1 - 0.17 12.7 0.2 1 10.1 0.0 2.6 2 0 0 2 2 1 0 ELM2 domain zf-HC5HC2H_2 PF13832.6 OQS03693.1 - 0.2 11.8 1.8 0.97 9.6 1.8 2.2 1 0 0 1 1 1 0 PHD-zinc-finger like domain zf-RING_2 PF13639.6 OQS03693.1 - 2.5 8.5 5.4 11 6.5 5.4 2.1 1 0 0 1 1 1 0 Ring finger domain Focadhesin PF11229.8 OQS03694.1 - 0.041 12.1 0.4 0.056 11.7 0.4 1.2 1 0 0 1 1 1 0 Focadhesin MutS_V PF00488.21 OQS03695.1 - 3.9e-77 258.5 0.1 9.9e-77 257.2 0.1 1.7 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 OQS03695.1 - 1.4e-26 93.9 1.6 4.6e-26 92.2 1.6 1.9 1 0 0 1 1 1 1 MutS domain III MutS_IV PF05190.18 OQS03695.1 - 4.3e-10 39.8 1.1 1e-09 38.6 1.1 1.7 1 0 0 1 1 1 1 MutS family domain IV MutS_II PF05188.17 OQS03695.1 - 0.00044 20.5 0.5 0.0023 18.2 0.2 2.4 2 0 0 2 2 2 1 MutS domain II WD40 PF00400.32 OQS03697.1 - 1.6e-24 85.7 11.7 2.1e-09 37.8 0.2 6.2 6 1 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OQS03697.1 - 1.9e-12 47.3 0.1 0.00025 21.3 0.1 3.8 2 1 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain IKI3 PF04762.12 OQS03697.1 - 0.012 13.7 0.1 2.8 5.8 0.0 2.8 1 1 3 4 4 4 0 IKI3 family PD40 PF07676.12 OQS03697.1 - 0.12 12.3 5.6 5.7 7.0 0.1 3.8 3 1 1 4 4 4 0 WD40-like Beta Propeller Repeat HAMP_N3 PF18575.1 OQS03697.1 - 0.14 11.7 0.0 0.25 10.9 0.0 1.3 1 0 0 1 1 1 0 HAMP N-terminal domain 3 Nefa_Nip30_N PF10187.9 OQS03698.1 - 9e-18 64.6 0.4 9e-18 64.6 0.4 1.4 2 0 0 2 2 2 1 N-terminal domain of NEFA-interacting nuclear protein NIP30 Arc_PepC PF06819.11 OQS03698.1 - 0.0092 16.1 0.1 0.015 15.4 0.1 1.4 1 0 0 1 1 1 1 Archaeal Peptidase A24 C-terminal Domain NopRA1 PF16201.5 OQS03699.1 - 9.3e-54 182.1 0.3 9.3e-54 182.1 0.3 5.0 6 0 0 6 6 6 1 Nucleolar pre-ribosomal-associated protein 1 Npa1 PF11707.8 OQS03699.1 - 4.6e-27 95.3 4.7 4.6e-27 95.3 4.7 2.8 2 0 0 2 2 2 1 Ribosome 60S biogenesis N-terminal Tom37 PF10568.9 OQS03699.1 - 0.95 9.8 4.3 47 4.3 0.1 4.1 5 0 0 5 5 5 0 Outer mitochondrial membrane transport complex protein Ada3 PF10198.9 OQS03700.1 - 6e-09 36.1 7.5 6e-09 36.1 7.5 3.1 3 1 0 3 3 3 1 Histone acetyltransferases subunit 3 TPR_2 PF07719.17 OQS03700.1 - 6.1e-06 26.0 1.5 0.0038 17.2 0.0 3.6 4 0 0 4 4 4 2 Tetratricopeptide repeat ANAPC3 PF12895.7 OQS03700.1 - 0.00012 22.2 4.2 0.00012 22.2 4.2 2.5 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 OQS03700.1 - 0.0017 18.9 3.9 1.2 9.9 0.1 3.7 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.6 OQS03700.1 - 0.0025 18.3 1.9 0.93 10.1 0.4 3.8 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 OQS03700.1 - 0.0025 17.9 3.9 1.4 9.3 0.0 4.4 5 0 0 5 5 5 2 Tetratricopeptide repeat HetR_C PF18460.1 OQS03700.1 - 0.073 13.0 2.2 0.2 11.6 0.1 2.8 3 0 0 3 3 3 0 Heterocyst differentiation regulator C-terminal Hood domain TPR_14 PF13428.6 OQS03700.1 - 0.075 13.9 0.8 43 5.3 0.0 3.6 3 1 1 4 4 4 0 Tetratricopeptide repeat GAGA_bind PF06217.12 OQS03700.1 - 1.5 9.1 8.2 4.9 7.3 3.4 2.3 2 0 0 2 2 2 0 GAGA binding protein-like family HgmA PF04209.13 OQS03701.1 - 2.2e-205 682.3 2.1 2.6e-205 682.1 2.1 1.0 1 0 0 1 1 1 1 homogentisate 1,2-dioxygenase Epimerase PF01370.21 OQS03702.1 - 6.5e-82 274.6 1.6 4.3e-23 82.0 0.0 4.4 4 1 0 4 4 4 4 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 OQS03702.1 - 5.6e-70 235.5 0.3 8.5e-22 77.5 0.0 4.1 3 1 1 4 4 4 4 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 OQS03702.1 - 4.3e-58 197.3 0.3 2.4e-15 56.8 0.0 4.9 5 1 0 5 5 5 4 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 OQS03702.1 - 3.9e-45 154.0 0.0 3.5e-11 43.3 0.0 4.4 4 0 0 4 4 4 4 NAD(P)H-binding NAD_binding_4 PF07993.12 OQS03702.1 - 4.7e-44 150.5 6.1 6.2e-12 45.2 0.0 6.1 4 3 0 4 4 4 4 Male sterility protein NmrA PF05368.13 OQS03702.1 - 7.7e-32 110.7 1.7 1.7e-07 31.0 0.0 4.7 5 0 0 5 5 5 4 NmrA-like family KR PF08659.10 OQS03702.1 - 2.6e-21 76.3 5.0 3.3e-05 23.9 0.1 5.1 3 2 1 4 4 4 4 KR domain adh_short PF00106.25 OQS03702.1 - 2e-18 66.5 3.7 0.0028 17.1 0.0 5.4 5 2 0 5 5 5 4 short chain dehydrogenase Polysacc_synt_2 PF02719.15 OQS03702.1 - 7.9e-13 48.2 0.1 0.0048 16.1 0.0 4.4 4 0 0 4 4 4 3 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 OQS03702.1 - 5.2e-10 38.9 0.9 0.24 10.5 0.0 4.7 4 0 0 4 4 4 4 RmlD substrate binding domain RELT PF12606.8 OQS03702.1 - 2.9e-07 29.4 6.7 1.1 8.3 0.0 4.4 4 0 0 4 4 4 4 Tumour necrosis factor receptor superfamily member 19 ELFV_dehydrog PF00208.21 OQS03702.1 - 4.5e-06 26.6 5.2 2.1 8.0 0.0 4.3 4 0 0 4 4 4 3 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Herpes_UL33 PF03581.13 OQS03702.1 - 8.7e-06 26.0 0.2 3.1 8.2 0.0 3.7 3 0 0 3 3 3 2 Herpesvirus UL33-like protein 3HCDH_N PF02737.18 OQS03702.1 - 0.00034 20.6 0.6 40 4.0 0.0 4.3 4 0 0 4 4 4 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_2 PF03446.15 OQS03702.1 - 0.0011 19.2 0.1 28 4.9 0.0 4.4 4 0 0 4 4 4 0 NAD binding domain of 6-phosphogluconate dehydrogenase ANAPC16 PF17256.2 OQS03702.1 - 0.0094 16.3 0.0 18 5.8 0.0 4.2 4 0 0 4 4 4 0 Anaphase-promoting complex, subunit 16 HTH_39 PF14090.6 OQS03702.1 - 0.044 13.5 0.1 50 3.7 0.0 3.8 4 0 0 4 4 4 0 Helix-turn-helix domain Mo25 PF08569.11 OQS03702.1 - 0.063 12.6 0.1 18 4.6 0.0 2.8 3 0 0 3 3 3 0 Mo25-like PHTB1_N PF14727.6 OQS03702.1 - 0.091 12.1 0.0 7 5.9 0.0 2.7 3 0 0 3 3 3 0 PTHB1 N-terminus NAD_binding_3 PF03447.16 OQS03702.1 - 0.12 13.0 0.4 53 4.5 0.0 4.1 4 0 0 4 4 4 0 Homoserine dehydrogenase, NAD binding domain Prenyltrans PF00432.21 OQS03702.1 - 0.19 11.5 1.5 51 3.7 0.0 3.9 4 0 0 4 4 4 0 Prenyltransferase and squalene oxidase repeat ApbA PF02558.16 OQS03702.1 - 0.6 9.7 4.5 57 3.3 0.1 4.1 5 0 0 5 5 4 0 Ketopantoate reductase PanE/ApbA Methyltrn_RNA_3 PF02598.17 OQS03703.1 - 3.8e-112 374.5 0.0 5.2e-112 374.0 0.0 1.2 1 0 0 1 1 1 1 Putative RNA methyltransferase GvpL_GvpF PF06386.11 OQS03703.1 - 0.045 13.7 4.1 0.062 13.2 4.1 1.2 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF SpoU_methylase PF00588.19 OQS03703.1 - 0.11 12.7 0.0 3 8.0 0.0 2.4 2 0 0 2 2 2 0 SpoU rRNA Methylase family Peptidase_S49_N PF08496.10 OQS03703.1 - 0.81 9.7 5.9 1.4 9.0 5.9 1.3 1 0 0 1 1 1 0 Peptidase family S49 N-terminal DTHCT PF08070.11 OQS03703.1 - 1 10.2 13.7 0.54 11.0 11.3 1.8 2 0 0 2 2 2 0 DTHCT (NUC029) region PHD PF00628.29 OQS03704.1 - 2.3e-09 37.0 7.2 2.3e-09 37.0 7.2 4.2 3 1 1 4 4 4 1 PHD-finger zf-RING_2 PF13639.6 OQS03704.1 - 0.0012 19.1 11.4 0.0012 19.1 11.4 4.7 4 0 0 4 4 4 2 Ring finger domain IstB_IS21_ATP PF08483.11 OQS03704.1 - 0.085 12.8 0.1 0.29 11.1 0.1 2.0 2 0 0 2 2 2 0 IstB-like ATP binding N-terminal HOOK PF05622.12 OQS03705.1 - 1e-22 80.2 64.9 2.9e-22 78.6 64.9 1.7 1 1 0 1 1 1 1 HOOK protein CENP-F_leu_zip PF10473.9 OQS03705.1 - 0.0091 16.0 8.4 0.0091 16.0 8.4 6.1 3 2 3 6 6 6 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 HALZ PF02183.18 OQS03705.1 - 0.22 11.8 0.1 0.22 11.8 0.1 7.7 8 1 0 8 8 8 0 Homeobox associated leucine zipper BLOC1_2 PF10046.9 OQS03705.1 - 3.5 8.0 50.1 0.57 10.5 5.8 7.0 1 1 2 6 6 6 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF5339 PF17274.2 OQS03706.1 - 0.16 12.8 10.3 0.43 11.5 0.8 3.6 3 0 0 3 3 3 0 Family of unknown function (DUF5339) Rotamase PF00639.21 OQS03706.1 - 0.17 12.9 1.6 0.98 10.4 1.5 2.4 1 1 0 1 1 1 0 PPIC-type PPIASE domain DASH_Dam1 PF08653.10 OQS03706.1 - 0.22 11.4 7.9 4.7 7.1 0.1 4.3 5 0 0 5 5 5 0 DASH complex subunit Dam1 Myosin_tail_1 PF01576.19 OQS03706.1 - 0.28 8.9 35.6 0.032 12.1 31.2 1.5 2 0 0 2 2 2 0 Myosin tail TPR_MLP1_2 PF07926.12 OQS03706.1 - 1.4 8.9 44.8 2.2 8.4 13.1 4.8 2 2 1 3 3 3 0 TPR/MLP1/MLP2-like protein Prp19 PF08606.11 OQS03706.1 - 4.4 7.4 13.3 0.088 12.8 1.3 3.7 4 0 0 4 4 4 0 Prp19/Pso4-like HMMR_N PF15905.5 OQS03706.1 - 7.9 5.8 36.7 0.85 9.0 7.0 3.5 2 1 1 3 3 3 0 Hyaluronan mediated motility receptor N-terminal Fe_hyd_lg_C PF02906.14 OQS03707.1 - 6.1e-67 225.8 2.3 2.6e-66 223.7 0.0 2.9 2 1 0 2 2 2 1 Iron only hydrogenase large subunit, C-terminal domain ABC_tran PF00005.27 OQS03707.1 - 6.1e-53 179.0 0.5 6.8e-26 91.4 0.1 3.0 2 0 0 2 2 2 2 ABC transporter DEAD PF00270.29 OQS03707.1 - 2.3e-48 164.3 0.0 9.3e-48 162.3 0.0 2.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase ABC2_membrane_3 PF12698.7 OQS03707.1 - 5.4e-41 140.8 53.7 1.6e-27 96.5 16.5 2.4 2 0 0 2 2 2 2 ABC-2 family transporter protein Helicase_C PF00271.31 OQS03707.1 - 5.8e-24 84.6 0.0 1.6e-22 80.0 0.0 3.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_21 PF13304.6 OQS03707.1 - 3e-22 79.8 6.8 5.3e-09 36.3 0.0 4.4 3 1 0 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system Fe_hyd_SSU PF02256.17 OQS03707.1 - 2e-08 34.2 0.0 4.8e-08 32.9 0.0 1.7 1 0 0 1 1 1 1 Iron hydrogenase small subunit DBP10CT PF08147.12 OQS03707.1 - 7.2e-07 29.4 5.4 1.9e-06 28.0 5.4 1.8 1 0 0 1 1 1 1 DBP10CT (NUC160) domain AAA_30 PF13604.6 OQS03707.1 - 4.8e-05 23.2 0.0 3.4 7.3 0.0 3.5 3 0 0 3 3 3 2 AAA domain RsgA_GTPase PF03193.16 OQS03707.1 - 6.3e-05 22.9 0.6 0.051 13.5 0.0 3.0 2 0 0 2 2 2 1 RsgA GTPase SMC_N PF02463.19 OQS03707.1 - 0.00014 21.3 0.0 3.8 6.9 0.0 3.8 3 2 0 3 3 2 2 RecF/RecN/SMC N terminal domain DUF4162 PF13732.6 OQS03707.1 - 0.0015 19.2 0.2 0.0089 16.7 0.1 2.6 2 0 0 2 2 1 1 Domain of unknown function (DUF4162) AAA_29 PF13555.6 OQS03707.1 - 0.0027 17.4 3.6 0.044 13.5 0.3 2.7 2 0 0 2 2 2 1 P-loop containing region of AAA domain SbcCD_C PF13558.6 OQS03707.1 - 0.0041 17.3 0.0 4.5 7.6 0.0 3.8 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_23 PF13476.6 OQS03707.1 - 0.0084 16.6 0.0 0.0084 16.6 0.0 4.2 3 1 1 4 4 2 1 AAA domain AAA_22 PF13401.6 OQS03707.1 - 0.056 13.7 0.9 9.6 6.5 0.0 3.8 3 1 0 3 3 3 0 AAA domain AAA PF00004.29 OQS03707.1 - 0.099 13.1 0.2 6.3 7.2 0.0 3.5 3 1 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) SRP54 PF00448.22 OQS03707.1 - 0.13 11.8 0.7 9.1 5.9 0.2 3.1 3 0 0 3 3 3 0 SRP54-type protein, GTPase domain MMR_HSR1 PF01926.23 OQS03707.1 - 0.32 11.1 3.9 11 6.2 0.1 3.3 4 0 0 4 4 2 0 50S ribosome-binding GTPase MukB PF04310.12 OQS03707.1 - 0.6 9.9 3.5 4.2 7.1 0.1 2.7 3 0 0 3 3 3 0 MukB N-terminal AAA_15 PF13175.6 OQS03707.1 - 1 9.0 19.7 0.35 10.5 0.1 4.6 4 1 1 5 5 4 0 AAA ATPase domain PDT PF00800.18 OQS03709.1 - 1.7e-16 60.5 0.1 3.6e-16 59.5 0.1 1.6 1 0 0 1 1 1 1 Prephenate dehydratase ACT PF01842.25 OQS03709.1 - 5.7e-07 29.2 0.0 1.9e-06 27.5 0.0 1.9 2 0 0 2 2 2 1 ACT domain CM_2 PF01817.21 OQS03709.1 - 0.018 15.4 1.8 0.36 11.2 0.2 2.5 2 0 0 2 2 2 0 Chorismate mutase type II UbiA PF01040.18 OQS03710.1 - 3.1e-49 167.6 20.7 4.1e-49 167.2 20.7 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family TrbC PF04956.13 OQS03710.1 - 0.019 15.2 2.0 0.019 15.2 2.0 2.8 3 1 0 3 3 3 0 TrbC/VIRB2 family Kinesin PF00225.23 OQS03711.1 - 3.2e-97 325.4 0.2 3.2e-97 325.4 0.2 2.4 2 1 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 OQS03711.1 - 3.9e-19 69.1 0.1 1.5e-18 67.2 0.1 2.1 1 0 0 1 1 1 1 Microtubule binding Kinesin_assoc PF16183.5 OQS03711.1 - 1e-16 61.6 7.6 1e-16 61.6 7.6 4.7 4 2 0 4 4 4 1 Kinesin-associated FHA PF00498.26 OQS03711.1 - 1e-05 25.8 0.0 2.4e-05 24.6 0.0 1.7 1 0 0 1 1 1 1 FHA domain KIF1B PF12423.8 OQS03711.1 - 1.2e-05 25.6 0.0 1.2e-05 25.6 0.0 2.6 2 0 0 2 2 2 1 Kinesin protein 1B Sec23_trunk PF04811.15 OQS03712.1 - 6.4e-74 248.6 0.0 9.2e-74 248.1 0.0 1.2 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.15 OQS03712.1 - 8.3e-20 70.5 0.0 1.5e-19 69.7 0.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 helical domain zf-Sec23_Sec24 PF04810.15 OQS03712.1 - 8.2e-17 61.0 5.2 1.7e-16 60.0 5.2 1.6 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Sec23_BS PF08033.12 OQS03712.1 - 4.1e-15 56.3 0.0 7.8e-15 55.4 0.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain Gelsolin PF00626.22 OQS03712.1 - 2.2e-08 33.9 0.0 5.4e-08 32.6 0.0 1.7 1 0 0 1 1 1 1 Gelsolin repeat VWA PF00092.28 OQS03712.1 - 0.15 12.3 0.2 0.44 10.8 0.1 1.8 2 0 0 2 2 2 0 von Willebrand factor type A domain Pkinase PF00069.25 OQS03713.1 - 1.8e-50 171.8 0.0 2.2e-50 171.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQS03713.1 - 1e-48 165.9 0.0 1.1e-48 165.7 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 OQS03713.1 - 2.2e-06 26.9 0.0 3.6e-06 26.2 0.0 1.4 1 1 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 OQS03713.1 - 0.026 13.8 0.0 0.13 11.5 0.0 1.8 2 0 0 2 2 2 0 Kinase-like Anoctamin PF04547.12 OQS03714.1 - 0 1256.6 117.7 1.7e-109 366.7 20.5 5.2 5 0 0 5 5 5 5 Calcium-activated chloride channel Anoct_dimer PF16178.5 OQS03714.1 - 7.8e-34 117.4 3.0 9.2e-11 41.9 0.0 7.6 7 1 0 8 8 8 7 Dimerisation domain of Ca+-activated chloride-channel, anoctamin EF-hand_13 PF17958.1 OQS03714.1 - 4e-32 109.9 0.1 9.9e-32 108.6 0.1 1.7 1 0 0 1 1 1 1 EF-hand domain EF-hand_7 PF13499.6 OQS03714.1 - 1.1e-15 57.9 2.0 1.2e-11 44.9 1.1 3.1 2 0 0 2 2 2 2 EF-hand domain pair eIF_4G1 PF12152.8 OQS03714.1 - 0.31 11.2 4.0 1.6 8.9 0.1 3.1 3 0 0 3 3 3 0 Eukaryotic translation initiation factor 4G1 CHCH PF06747.13 OQS03715.1 - 0.0012 18.9 3.7 0.0019 18.3 3.7 1.2 1 0 0 1 1 1 1 CHCH domain Sin3_corepress PF08295.12 OQS03715.1 - 0.0021 18.1 0.0 0.0022 18.0 0.0 1.1 1 0 0 1 1 1 1 Sin3 family co-repressor NDUF_B7 PF05676.13 OQS03715.1 - 0.005 16.5 3.3 0.0062 16.2 3.3 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) MTCP1 PF08991.10 OQS03715.1 - 0.0067 16.6 4.8 0.009 16.2 4.8 1.2 1 0 0 1 1 1 1 Mature-T-Cell Proliferation I type UCR_hinge PF02320.16 OQS03715.1 - 0.04 14.1 4.6 0.17 12.1 0.2 2.1 1 1 1 2 2 2 0 Ubiquinol-cytochrome C reductase hinge protein Phytase PF02333.15 OQS03716.1 - 0.033 13.2 0.1 0.051 12.5 0.1 1.2 1 0 0 1 1 1 0 Phytase DNA_pol_B_N PF18094.1 OQS03717.1 - 0.011 16.3 0.0 0.013 16.1 0.0 1.1 1 0 0 1 1 1 0 DNA polymerase beta N-terminal domain Shikimate_dh_N PF08501.11 OQS03717.1 - 0.098 12.9 0.0 0.13 12.5 0.0 1.3 1 0 0 1 1 1 0 Shikimate dehydrogenase substrate binding domain Flag1_repress PF03614.13 OQS03718.1 - 0.1 12.4 0.0 0.14 12.0 0.0 1.2 1 0 0 1 1 1 0 Repressor of phase-1 flagellin DUF2685 PF10886.8 OQS03721.1 - 0.11 12.7 0.1 0.52 10.5 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2685) Eno-Rase_FAD_bd PF07055.12 OQS03722.1 - 0.13 12.7 0.0 0.3 11.5 0.0 1.6 1 0 0 1 1 1 0 Enoyl reductase FAD binding domain PPR_3 PF13812.6 OQS03723.1 - 0.075 13.1 0.2 0.17 12.0 0.2 1.6 1 0 0 1 1 1 0 Pentatricopeptide repeat domain Ank_2 PF12796.7 OQS03724.1 - 6e-07 30.0 0.1 8.7e-07 29.4 0.1 1.2 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OQS03724.1 - 0.0093 16.3 0.1 1.8 9.0 0.0 3.1 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 OQS03724.1 - 0.021 15.4 0.1 0.81 10.3 0.0 2.4 1 1 1 2 2 2 0 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQS03724.1 - 0.036 14.6 0.0 2.3 9.1 0.0 2.9 2 1 1 3 3 3 0 Ankyrin repeat ERCC4 PF02732.15 OQS03725.1 - 0.00063 20.0 0.0 0.0013 19.0 0.0 1.6 1 0 0 1 1 1 1 ERCC4 domain HHH_3 PF12836.7 OQS03725.1 - 0.034 14.4 0.0 0.1 12.8 0.0 1.8 1 0 0 1 1 1 0 Helix-hairpin-helix motif Ank_4 PF13637.6 OQS03726.1 - 3.3e-55 183.8 23.3 1.3e-06 28.9 0.1 13.8 9 3 5 15 15 15 14 Ankyrin repeats (many copies) Ank_2 PF12796.7 OQS03726.1 - 2.4e-52 175.4 49.4 6.8e-09 36.2 0.8 10.5 3 2 10 13 13 13 13 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OQS03726.1 - 5.2e-44 147.7 30.0 0.038 14.3 0.2 19.1 5 4 15 20 20 20 14 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQS03726.1 - 5.9e-31 103.0 17.6 0.24 12.1 0.0 18.8 18 2 2 20 20 20 9 Ankyrin repeat Ank PF00023.30 OQS03726.1 - 0.00076 19.8 17.5 49 4.6 0.2 12.1 8 5 2 10 10 10 0 Ankyrin repeat AhpC-TSA PF00578.21 OQS03726.1 - 0.0035 17.2 0.6 16 5.4 0.0 4.7 3 2 2 5 5 5 1 AhpC/TSA family DUF1979 PF09322.10 OQS03726.1 - 0.032 14.1 0.0 7.7 6.5 0.0 3.8 4 0 0 4 4 4 0 Domain of unknown function (DUF1979) CNOT1_HEAT PF16418.5 OQS03726.1 - 0.064 13.3 0.3 55 3.8 0.0 5.0 6 0 0 6 6 6 0 CCR4-NOT transcription complex subunit 1 HEAT repeat DUF3447 PF11929.8 OQS03726.1 - 0.12 12.3 19.6 0.54 10.3 0.1 6.2 6 2 0 6 6 6 0 Domain of unknown function (DUF3447) Neugrin PF06413.11 OQS03726.1 - 0.27 11.2 0.1 29 4.6 0.0 3.0 3 1 1 4 4 4 0 Neugrin PXA PF02194.15 OQS03727.1 - 1.5e-18 67.4 2.7 7.2e-18 65.2 0.1 2.6 2 0 0 2 2 2 1 PXA domain Nexin_C PF08628.12 OQS03727.1 - 2e-10 41.2 0.0 8.5e-10 39.2 0.0 2.2 1 0 0 1 1 1 1 Sorting nexin C terminal RUN PF02759.19 OQS03727.1 - 3.4e-05 23.8 0.1 0.00011 22.2 0.1 1.9 1 1 0 1 1 1 1 RUN domain VASP_tetra PF08776.11 OQS03728.1 - 5.2e-06 25.9 6.0 0.0032 17.0 0.1 3.7 3 0 0 3 3 3 2 VASP tetramerisation domain JIP_LZII PF16471.5 OQS03728.1 - 0.019 15.1 2.0 0.019 15.1 2.0 6.4 4 2 3 7 7 7 0 JNK-interacting protein leucine zipper II BRE1 PF08647.11 OQS03730.1 - 3.4e-13 49.5 10.1 3.4e-13 49.5 10.1 11.0 5 3 5 10 10 10 2 BRE1 E3 ubiquitin ligase Utp12 PF04003.12 OQS03731.1 - 5e-20 71.8 0.1 8.8e-20 71.0 0.1 1.4 1 0 0 1 1 1 1 Dip2/Utp12 Family WD40 PF00400.32 OQS03731.1 - 1e-06 29.3 5.4 1.5 9.8 0.0 5.3 5 0 0 5 5 5 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OQS03731.1 - 2.5e-06 27.7 0.3 0.32 11.3 0.1 3.7 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain HPS3_N PF14761.6 OQS03731.1 - 0.093 12.3 0.0 0.3 10.6 0.0 1.8 1 1 0 1 1 1 0 Hermansky-Pudlak syndrome 3 TFIIA PF03153.13 OQS03731.1 - 0.23 11.4 10.4 1.4 8.8 3.4 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Sigma70_ner PF04546.13 OQS03731.1 - 5.2 6.9 16.5 0.6 9.9 3.2 2.3 2 0 0 2 2 2 0 Sigma-70, non-essential region DUF4820 PF16091.5 OQS03731.1 - 6.3 6.1 10.0 13 5.1 0.3 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4820) Peptidase_M16_M PF16187.5 OQS03733.1 - 4.8e-36 124.5 3.3 8.8e-36 123.6 3.3 1.4 1 0 0 1 1 1 1 Middle or third domain of peptidase_M16 Peptidase_M16 PF00675.20 OQS03733.1 - 6.7e-32 110.5 0.0 2.6e-31 108.6 0.0 2.0 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 OQS03733.1 - 6.2e-18 65.5 0.0 4.1e-09 36.7 0.0 2.4 2 0 0 2 2 2 2 Peptidase M16 inactive domain WD40 PF00400.32 OQS03734.1 - 0.0016 19.2 0.0 9.7 7.3 0.0 4.6 4 0 0 4 4 4 1 WD domain, G-beta repeat Pkinase_Tyr PF07714.17 OQS03735.1 - 1.7e-15 57.0 0.0 3e-15 56.2 0.0 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OQS03735.1 - 5.7e-12 45.6 0.0 8e-12 45.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQS03736.1 - 1.1e-09 38.0 1.0 8.2e-09 35.1 1.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OQS03736.1 - 5.5e-08 32.5 0.3 9.7e-08 31.7 0.3 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQS03737.1 - 1.5e-48 165.3 4.6 1.7e-24 86.5 0.1 4.1 3 1 1 4 4 4 4 Protein tyrosine kinase Pkinase PF00069.25 OQS03737.1 - 1.3e-44 152.5 1.5 8.1e-25 87.7 0.1 3.9 3 1 0 3 3 3 2 Protein kinase domain Kdo PF06293.14 OQS03737.1 - 3.4e-05 23.3 1.8 0.068 12.5 0.2 2.3 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family Spo7 PF03907.13 OQS03738.1 - 0.14 11.6 0.1 0.17 11.3 0.1 1.1 1 0 0 1 1 1 0 Spo7-like protein Pkinase_Tyr PF07714.17 OQS03740.1 - 2.5e-48 164.6 0.1 3.6e-48 164.1 0.1 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OQS03740.1 - 2.3e-46 158.3 0.0 3.6e-46 157.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain TMEM154 PF15102.6 OQS03740.1 - 5e-05 23.2 1.4 0.022 14.7 0.1 2.8 3 0 0 3 3 2 1 TMEM154 protein family RCR PF12273.8 OQS03740.1 - 5.1e-05 23.9 6.5 0.023 15.3 1.4 2.4 2 0 0 2 2 2 2 Chitin synthesis regulation, resistance to Congo red Pkinase_fungal PF17667.1 OQS03740.1 - 0.00016 20.6 0.2 0.00026 19.9 0.2 1.2 1 0 0 1 1 1 1 Fungal protein kinase FtsX PF02687.21 OQS03740.1 - 0.00026 21.4 0.7 0.41 11.1 0.2 2.5 2 0 0 2 2 2 2 FtsX-like permease family DUF4834 PF16118.5 OQS03740.1 - 0.00035 21.5 2.1 0.76 10.8 0.3 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF4834) MLANA PF14991.6 OQS03740.1 - 0.00049 20.4 1.0 0.15 12.3 0.1 2.4 2 0 0 2 2 2 1 Protein melan-A ETRAMP PF09716.10 OQS03740.1 - 0.0017 18.3 4.6 0.016 15.3 0.2 3.0 3 0 0 3 3 3 1 Malarial early transcribed membrane protein (ETRAMP) Glycophorin_A PF01102.18 OQS03740.1 - 0.0051 17.0 1.0 3.2 8.0 0.0 2.8 2 0 0 2 2 2 1 Glycophorin A Oxidored_q2 PF00420.24 OQS03740.1 - 0.006 16.2 0.4 0.55 9.9 0.1 2.5 2 0 0 2 2 2 1 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L DUF4448 PF14610.6 OQS03740.1 - 0.009 15.8 5.1 0.29 10.9 3.0 3.1 2 1 0 2 2 2 1 Protein of unknown function (DUF4448) DAG1 PF05454.11 OQS03740.1 - 0.011 15.1 0.8 0.71 9.2 0.1 2.4 2 0 0 2 2 2 0 Dystroglycan (Dystrophin-associated glycoprotein 1) DUF4131 PF13567.6 OQS03740.1 - 0.012 15.3 0.2 0.62 9.7 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) Shisa PF13908.6 OQS03740.1 - 0.012 15.9 14.1 0.081 13.2 3.8 2.5 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator DUF3377 PF11857.8 OQS03740.1 - 0.015 15.2 2.7 4.1 7.4 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3377) ASFV_J13L PF05568.11 OQS03740.1 - 0.016 14.9 4.0 0.073 12.8 0.5 2.4 2 0 0 2 2 2 0 African swine fever virus J13L protein DUF2371 PF10177.9 OQS03740.1 - 0.02 15.1 0.5 2.4 8.3 0.1 2.6 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2371) DUF2207 PF09972.9 OQS03740.1 - 0.023 13.5 0.1 4.8 5.8 0.0 2.2 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) CD34_antigen PF06365.12 OQS03740.1 - 0.029 13.9 1.8 2.1 7.9 0.2 2.3 2 0 0 2 2 2 0 CD34/Podocalyxin family EphA2_TM PF14575.6 OQS03740.1 - 0.029 15.2 0.9 4 8.4 0.1 2.7 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain GAPT PF11770.8 OQS03740.1 - 0.03 14.2 2.9 1.6 8.6 1.9 3.0 2 1 0 2 2 2 0 GRB2-binding adapter (GAPT) Insulin_TMD PF17870.1 OQS03740.1 - 0.046 13.8 12.6 0.045 13.8 2.5 2.6 2 0 0 2 2 2 0 Insulin receptor trans-membrane segment Mid2 PF04478.12 OQS03740.1 - 0.053 13.4 2.0 4.1 7.2 0.2 2.6 2 0 0 2 2 2 0 Mid2 like cell wall stress sensor Chordopox_A13L PF05961.11 OQS03740.1 - 0.073 13.3 8.5 0.43 10.8 0.7 2.7 2 0 0 2 2 2 0 Chordopoxvirus A13L protein DUF4713 PF15831.5 OQS03740.1 - 0.095 13.2 5.7 1.8 9.1 0.8 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4713) DUF5113 PF17140.4 OQS03740.1 - 0.097 12.5 2.3 1.9 8.3 0.2 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF5113) RIFIN PF02009.16 OQS03740.1 - 0.15 11.9 1.6 11 5.8 0.0 2.6 2 0 0 2 2 2 0 Rifin Orf78 PF06024.12 OQS03740.1 - 0.2 12.0 6.6 5 7.5 0.1 3.0 3 0 0 3 3 2 0 Orf78 (ac78) DUF2116 PF09889.9 OQS03740.1 - 0.28 11.2 1.4 33 4.6 0.3 2.7 2 0 0 2 2 2 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) DUF3290 PF11694.8 OQS03740.1 - 0.37 10.8 9.2 0.081 12.9 0.7 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF3290) Saf_2TM PF18303.1 OQS03740.1 - 0.73 9.4 5.1 2.2 7.9 0.2 2.8 3 0 0 3 3 3 0 SAVED-fused 2TM effector domain ECSCR PF15820.5 OQS03740.1 - 1.6 8.6 6.3 3.4 7.5 0.3 2.5 2 0 0 2 2 2 0 Endothelial cell-specific chemotaxis regulator DUF5385 PF17359.2 OQS03740.1 - 1.7 8.2 6.2 15 5.1 0.1 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5385) SNARE PF05739.19 OQS03740.1 - 4.1 7.5 9.7 0.47 10.5 0.1 2.5 2 0 0 2 2 2 0 SNARE domain DUF4064 PF13273.6 OQS03740.1 - 4.3 7.7 11.0 8.5 6.7 0.2 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF4064) PH PF00169.29 OQS03741.1 - 3.4e-07 30.7 0.4 1.1e-06 29.1 0.1 2.1 2 0 0 2 2 2 1 PH domain UFC1 PF08694.11 OQS03741.1 - 0.95 9.1 2.6 50 3.5 0.0 3.5 4 0 0 4 4 4 0 Ubiquitin-fold modifier-conjugating enzyme 1 WW PF00397.26 OQS03741.1 - 1.4 9.0 4.6 0.18 12.0 0.2 1.8 2 0 0 2 2 2 0 WW domain TrkA_N PF02254.18 OQS03741.1 - 2.1 8.7 4.8 13 6.1 0.3 3.1 3 0 0 3 3 3 0 TrkA-N domain DUF2278 PF10042.9 OQS03741.1 - 3.2 7.7 6.3 15 5.5 0.5 3.7 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2278) GLTP PF08718.11 OQS03741.1 - 3.4 7.9 8.5 0.27 11.5 0.5 3.2 3 0 0 3 3 3 0 Glycolipid transfer protein (GLTP) CRPA PF05745.11 OQS03742.1 - 1.9 8.5 7.3 2.2 8.3 1.2 3.1 3 0 0 3 3 3 0 Chlamydia 15 kDa cysteine-rich outer membrane protein (CRPA) PH PF00169.29 OQS03743.1 - 2.6e-10 40.7 0.0 8.7e-10 39.1 0.0 1.9 2 0 0 2 2 2 1 PH domain PH_8 PF15409.6 OQS03743.1 - 0.0075 16.5 0.0 0.037 14.3 0.0 2.1 1 1 0 1 1 1 1 Pleckstrin homology domain PH_6 PF15406.6 OQS03743.1 - 0.0077 16.5 0.0 0.064 13.6 0.0 2.5 1 1 0 1 1 1 1 Pleckstrin homology domain PH_11 PF15413.6 OQS03743.1 - 0.025 15.0 0.4 0.14 12.6 0.0 2.5 2 1 0 2 2 2 0 Pleckstrin homology domain GAS PF13851.6 OQS03743.1 - 0.17 11.2 13.6 0.065 12.6 6.1 2.3 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding DUF4047 PF13256.6 OQS03743.1 - 0.34 11.1 4.4 0.11 12.6 0.8 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4047) Spc7 PF08317.11 OQS03743.1 - 1.1 8.0 12.5 2 7.2 12.5 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein Sugarporin_N PF11471.8 OQS03743.1 - 4.6 7.3 12.7 7.9 6.5 5.1 2.7 2 0 0 2 2 2 0 Maltoporin periplasmic N-terminal extension HA PF03457.14 OQS03744.1 - 6.1e-36 122.6 2.1 1.2e-09 38.4 0.0 4.3 4 0 0 4 4 4 4 Helicase associated domain TRAP_beta PF05753.14 OQS03744.1 - 0.13 11.7 0.0 20 4.5 0.0 3.5 4 0 0 4 4 4 0 Translocon-associated protein beta (TRAPB) FPP PF05911.11 OQS03745.1 - 0.016 13.4 14.5 0.021 13.1 14.5 1.1 1 0 0 1 1 1 0 Filament-like plant protein, long coiled-coil FAM92 PF06730.11 OQS03745.1 - 0.026 13.9 8.2 0.034 13.6 8.2 1.1 1 0 0 1 1 1 0 FAM92 protein TPR_MLP1_2 PF07926.12 OQS03745.1 - 0.027 14.5 8.7 0.027 14.5 8.7 2.4 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein GRDB PF07355.12 OQS03745.1 - 0.042 13.1 0.4 0.054 12.7 0.4 1.1 1 0 0 1 1 1 0 Glycine/sarcosine/betaine reductase selenoprotein B (GRDB) Spc7 PF08317.11 OQS03745.1 - 0.2 10.5 14.9 0.36 9.7 14.9 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF4795 PF16043.5 OQS03745.1 - 0.31 10.6 13.8 0.42 10.2 13.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4795) ADIP PF11559.8 OQS03745.1 - 0.33 11.0 19.8 0.075 13.1 9.8 2.1 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding Uso1_p115_C PF04871.13 OQS03745.1 - 0.5 10.7 16.6 0.16 12.3 5.3 2.1 1 1 1 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region Filament PF00038.21 OQS03745.1 - 0.57 9.7 18.9 2 7.9 5.7 2.1 1 1 0 2 2 2 0 Intermediate filament protein bZIP_1 PF00170.21 OQS03745.1 - 0.6 10.2 15.4 0.51 10.5 1.0 3.6 2 2 1 3 3 3 0 bZIP transcription factor FUSC PF04632.12 OQS03745.1 - 0.9 8.0 6.4 1.1 7.6 6.4 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family BLOC1_2 PF10046.9 OQS03745.1 - 0.91 9.9 12.3 4.6 7.6 3.3 2.3 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 ATG16 PF08614.11 OQS03745.1 - 0.99 9.6 24.5 0.33 11.2 11.3 2.1 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) Mt_ATP-synt_D PF05873.12 OQS03745.1 - 1 9.2 6.7 1.4 8.8 0.7 2.1 1 1 1 2 2 2 0 ATP synthase D chain, mitochondrial (ATP5H) GAS PF13851.6 OQS03745.1 - 1 8.7 18.9 1.6 8.0 17.6 1.8 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Prominin PF05478.11 OQS03745.1 - 1 7.2 10.7 2 6.3 10.7 1.5 1 1 0 1 1 1 0 Prominin V_ATPase_I PF01496.19 OQS03745.1 - 1.3 6.9 8.3 1.7 6.5 8.3 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family YabA PF06156.13 OQS03745.1 - 1.5 9.5 16.3 0.07 13.8 1.8 2.8 1 1 1 2 2 1 0 Initiation control protein YabA DUF4164 PF13747.6 OQS03745.1 - 2 8.8 19.8 2.3 8.6 4.8 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4164) COG2 PF06148.11 OQS03745.1 - 2 8.5 11.2 1 9.5 3.5 2.3 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 HalX PF08663.10 OQS03745.1 - 2.1 8.7 18.6 0.14 12.5 6.4 3.1 2 1 0 2 2 2 0 HalX domain Cortex-I_coil PF09304.10 OQS03745.1 - 2.3 8.5 15.1 0.49 10.6 4.2 2.3 1 1 1 2 2 2 0 Cortexillin I, coiled coil SHE3 PF17078.5 OQS03745.1 - 2.7 7.7 17.1 5 6.8 5.8 2.8 1 1 2 3 3 3 0 SWI5-dependent HO expression protein 3 APG6_N PF17675.1 OQS03745.1 - 3.1 8.3 25.7 26 5.3 16.2 2.5 1 1 1 2 2 2 0 Apg6 coiled-coil region DUF3450 PF11932.8 OQS03745.1 - 3.3 7.0 19.4 1.2 8.4 9.2 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) DUF1664 PF07889.12 OQS03745.1 - 4 7.5 11.4 1.7 8.7 3.2 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) BST2 PF16716.5 OQS03745.1 - 4.1 8.1 16.2 1.6 9.4 9.3 2.9 1 1 1 2 2 2 0 Bone marrow stromal antigen 2 DivIC PF04977.15 OQS03745.1 - 5 7.0 18.8 0.42 10.4 5.7 3.6 2 2 1 3 3 3 0 Septum formation initiator ZapB PF06005.12 OQS03745.1 - 5.4 7.5 24.7 3.9 8.0 4.0 3.2 2 1 1 3 3 3 0 Cell division protein ZapB BRE1 PF08647.11 OQS03745.1 - 5.9 7.0 15.4 1 9.5 9.4 2.6 1 1 0 2 2 2 0 BRE1 E3 ubiquitin ligase HIP1_clath_bdg PF16515.5 OQS03745.1 - 6.1 7.5 21.7 1.5 9.5 8.1 2.7 1 1 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 JIP_LZII PF16471.5 OQS03745.1 - 6.1 7.1 16.8 1.2 9.4 2.3 3.2 2 2 1 3 3 3 0 JNK-interacting protein leucine zipper II TolA_bind_tri PF16331.5 OQS03745.1 - 7.2 6.8 24.0 1.6 8.9 8.2 3.4 1 1 2 3 3 3 0 TolA binding protein trimerisation Metal_resist PF13801.6 OQS03745.1 - 7.2 6.8 11.5 0.17 12.1 2.1 2.5 1 1 1 3 3 3 0 Heavy-metal resistance Spc24 PF08286.11 OQS03745.1 - 9.3 6.6 19.8 4.6 7.5 7.6 3.2 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 Glyco_hydro81C PF17652.1 OQS03747.1 - 9.9e-80 268.4 3.9 1.3e-79 268.0 3.9 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 C-terminal domain Glyco_hydro_81 PF03639.13 OQS03747.1 - 7.3e-42 143.7 1.7 1.2e-41 143.0 1.7 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 N-terminal domain Adeno_E3_CR2 PF02439.15 OQS03747.1 - 0.018 14.8 6.3 0.048 13.4 6.3 1.7 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Trypsin_2 PF13365.6 OQS03748.1 - 2.9e-25 89.9 2.4 5.8e-13 50.0 0.2 2.5 2 0 0 2 2 2 2 Trypsin-like peptidase domain Ricin_B_lectin PF00652.22 OQS03748.1 - 2.3e-18 66.6 25.3 7.3e-11 42.4 3.3 3.7 4 0 0 4 4 4 2 Ricin-type beta-trefoil lectin domain Peptidase_S46 PF10459.9 OQS03748.1 - 1.4 7.5 5.0 5.2 5.6 0.2 2.8 3 0 0 3 3 3 0 Peptidase S46 SET PF00856.28 OQS03749.1 - 8e-11 42.6 0.0 1.5e-10 41.7 0.0 1.5 1 0 0 1 1 1 1 SET domain zinc-ribbons_6 PF07191.12 OQS03749.1 - 0.049 13.6 5.0 0.088 12.8 4.2 1.9 1 1 0 1 1 1 0 zinc-ribbons Pkinase PF00069.25 OQS03750.1 - 1.6e-47 162.1 0.0 2.2e-47 161.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQS03750.1 - 3.4e-47 160.9 0.0 6.1e-47 160.1 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OQS03750.1 - 0.029 13.2 0.0 0.046 12.5 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Haspin_kinase PF12330.8 OQS03750.1 - 0.029 13.3 0.0 0.079 11.9 0.0 1.7 1 1 0 1 1 1 0 Haspin like kinase domain Rax2 PF12768.7 OQS03750.1 - 0.073 12.5 0.0 0.15 11.5 0.0 1.5 1 0 0 1 1 1 0 Cortical protein marker for cell polarity Kdo PF06293.14 OQS03750.1 - 0.09 12.1 0.0 0.16 11.3 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 OQS03750.1 - 0.11 11.8 0.0 0.22 10.8 0.0 1.4 1 0 0 1 1 1 0 Kinase-like Pkinase_Tyr PF07714.17 OQS03751.1 - 2.2e-115 384.4 0.0 2e-39 135.5 0.0 3.1 3 0 0 3 3 3 3 Protein tyrosine kinase Pkinase PF00069.25 OQS03751.1 - 1.3e-109 365.7 0.0 4.7e-37 127.8 0.0 3.1 3 0 0 3 3 3 3 Protein kinase domain fn3_2 PF16893.5 OQS03751.1 - 5.3e-06 26.5 0.0 1.3 9.2 0.0 3.8 3 0 0 3 3 3 3 Fibronectin type III domain EcpB_C PF18649.1 OQS03751.1 - 0.021 14.8 0.1 15 5.6 0.0 3.2 3 0 0 3 3 3 0 EcpB C-terminal domain DUF4745 PF15923.5 OQS03751.1 - 0.034 14.1 0.1 2 8.4 0.0 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4745) Toprim_Crpt PF13342.6 OQS03751.1 - 0.035 14.1 2.5 3.4 7.7 0.1 3.3 3 0 0 3 3 3 0 C-terminal repeat of topoisomerase PUB PF09409.10 OQS03752.1 - 6.6e-17 61.2 0.0 9.3e-17 60.7 0.0 1.2 1 0 0 1 1 1 1 PUB domain VirK PF06903.12 OQS03752.1 - 0.15 12.1 0.0 1.6 8.9 0.0 2.0 1 1 0 2 2 2 0 VirK protein Thioredoxin PF00085.20 OQS03753.1 - 1.5e-22 79.5 0.0 3.1e-22 78.5 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin UBA PF00627.31 OQS03753.1 - 1.7e-07 31.0 0.0 3.4e-07 30.0 0.0 1.6 1 0 0 1 1 1 1 UBA/TS-N domain Thioredoxin_2 PF13098.6 OQS03753.1 - 2.7e-06 27.8 0.0 3.3e-05 24.3 0.0 2.5 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_7 PF13899.6 OQS03753.1 - 4.8e-05 23.4 0.0 0.00013 22.1 0.0 1.7 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_8 PF13905.6 OQS03753.1 - 7.5e-05 23.0 0.0 0.00016 21.9 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_9 PF14595.6 OQS03753.1 - 0.00054 19.7 0.7 0.0024 17.6 0.0 2.2 2 0 0 2 2 2 1 Thioredoxin UIM PF02809.20 OQS03753.1 - 0.0077 16.1 4.8 0.02 14.8 4.8 1.7 1 0 0 1 1 1 1 Ubiquitin interaction motif IBD PF10416.9 OQS03753.1 - 0.013 15.6 0.3 0.043 13.8 0.0 2.0 2 0 0 2 2 2 0 Transcription-initiator DNA-binding domain IBD AhpC-TSA PF00578.21 OQS03753.1 - 0.042 13.8 0.0 0.11 12.5 0.0 1.6 1 0 0 1 1 1 0 AhpC/TSA family Glutaredoxin PF00462.24 OQS03753.1 - 0.09 13.0 0.2 0.4 10.9 0.0 2.1 2 1 0 2 2 2 0 Glutaredoxin DUF4813 PF16072.5 OQS03753.1 - 0.13 11.9 4.9 0.18 11.4 4.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4813) L_lactis_ph-MCP PF06673.11 OQS03753.1 - 4 6.3 6.8 6 5.8 6.8 1.2 1 0 0 1 1 1 0 Lactococcus lactis bacteriophage major capsid protein Spt5_N PF11942.8 OQS03753.1 - 5.4 8.1 10.9 0.93 10.5 7.1 1.6 2 0 0 2 2 1 0 Spt5 transcription elongation factor, acidic N-terminal Guanylate_cyc PF00211.20 OQS03754.1 - 4.9e-23 81.7 0.4 3e-13 49.8 0.0 2.8 3 0 0 3 3 3 2 Adenylate and Guanylate cyclase catalytic domain AAA_16 PF13191.6 OQS03754.1 - 5.3e-10 39.9 0.2 0.0016 18.8 0.0 2.9 2 0 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 OQS03754.1 - 0.00057 20.2 0.0 0.084 13.1 0.0 3.1 2 0 0 2 2 2 1 AAA domain Rad17 PF03215.15 OQS03754.1 - 0.0054 16.7 0.0 0.013 15.4 0.0 1.6 1 0 0 1 1 1 1 Rad17 P-loop domain RsgA_GTPase PF03193.16 OQS03754.1 - 0.017 15.0 0.0 0.06 13.2 0.0 2.0 1 0 0 1 1 1 0 RsgA GTPase ABC_tran PF00005.27 OQS03754.1 - 0.021 15.3 0.0 0.058 13.9 0.0 1.7 1 0 0 1 1 1 0 ABC transporter AAA_18 PF13238.6 OQS03754.1 - 0.031 14.8 0.0 0.089 13.3 0.0 1.8 1 0 0 1 1 1 0 AAA domain R3H PF01424.22 OQS03754.1 - 0.032 14.2 0.1 0.095 12.7 0.1 1.8 1 0 0 1 1 1 0 R3H domain MCM PF00493.23 OQS03754.1 - 0.052 12.6 0.0 0.11 11.5 0.0 1.5 1 0 0 1 1 1 0 MCM P-loop domain AAA_33 PF13671.6 OQS03754.1 - 0.12 12.5 0.1 0.4 10.8 0.1 1.9 1 0 0 1 1 1 0 AAA domain Beta-lactamase PF00144.24 OQS03755.1 - 3.2e-17 62.8 0.0 4.7e-17 62.2 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase Pkinase PF00069.25 OQS03756.1 - 1.3e-69 234.5 0.5 1.7e-69 234.2 0.5 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQS03756.1 - 1.2e-35 123.1 0.6 1.6e-35 122.7 0.6 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase EF-hand_1 PF00036.32 OQS03756.1 - 1.2e-10 40.2 0.9 8.8e-06 24.9 0.1 3.4 3 0 0 3 3 3 2 EF hand EF-hand_7 PF13499.6 OQS03756.1 - 1.1e-08 35.4 0.3 0.0076 16.7 0.0 2.7 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 OQS03756.1 - 3.5e-08 32.7 0.1 0.12 12.4 0.0 3.7 3 0 0 3 3 3 3 EF-hand domain Kinase-like PF14531.6 OQS03756.1 - 1.7e-06 27.6 0.0 4.4e-06 26.2 0.0 1.7 2 0 0 2 2 2 1 Kinase-like EF-hand_8 PF13833.6 OQS03756.1 - 3.3e-06 26.9 0.3 0.0053 16.6 0.1 2.5 2 0 0 2 2 2 2 EF-hand domain pair Kdo PF06293.14 OQS03756.1 - 8e-06 25.3 0.2 1.4e-05 24.6 0.2 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family EF-hand_5 PF13202.6 OQS03756.1 - 0.0048 16.3 0.4 0.063 12.8 0.1 2.6 2 0 0 2 2 2 1 EF hand EF-hand_4 PF12763.7 OQS03756.1 - 0.043 13.8 0.9 2.7 8.0 0.2 2.6 1 1 2 3 3 3 0 Cytoskeletal-regulatory complex EF hand APH PF01636.23 OQS03756.1 - 0.048 13.6 0.0 7.7 6.3 0.0 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family FTA2 PF13095.6 OQS03756.1 - 0.35 10.5 1.9 11 5.6 0.0 3.2 3 1 1 4 4 4 0 Kinetochore Sim4 complex subunit FTA2 EF-hand_7 PF13499.6 OQS03757.1 - 5.2e-23 81.3 4.9 2.6e-08 34.2 0.3 3.6 3 0 0 3 3 3 3 EF-hand domain pair EF-hand_1 PF00036.32 OQS03757.1 - 4.5e-19 66.5 6.1 0.00049 19.5 0.3 5.7 5 0 0 5 5 5 4 EF hand EF-hand_6 PF13405.6 OQS03757.1 - 2.4e-18 64.4 8.3 0.0014 18.4 0.0 5.8 5 0 0 5 5 5 5 EF-hand domain EF-hand_8 PF13833.6 OQS03757.1 - 1e-13 50.9 7.6 0.0001 22.1 0.0 5.4 4 2 2 6 6 6 4 EF-hand domain pair EF-hand_5 PF13202.6 OQS03757.1 - 8.1e-08 31.4 5.8 0.29 10.7 0.1 5.2 5 0 0 5 5 5 3 EF hand SPARC_Ca_bdg PF10591.9 OQS03757.1 - 4.2e-05 23.8 6.5 0.21 11.9 0.3 3.9 4 1 0 4 4 4 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_9 PF14658.6 OQS03757.1 - 0.0033 17.7 0.1 0.014 15.7 0.0 2.0 2 0 0 2 2 2 1 EF-hand domain EF-hand_4 PF12763.7 OQS03757.1 - 0.071 13.1 0.9 0.28 11.1 0.1 2.4 2 1 0 2 2 2 0 Cytoskeletal-regulatory complex EF hand Di19_C PF14571.6 OQS03757.1 - 0.18 12.4 5.2 2.5 8.7 1.4 2.6 2 0 0 2 2 2 0 Stress-induced protein Di19, C-terminal Rcd1 PF04078.13 OQS03758.1 - 0.01 15.2 0.1 0.016 14.5 0.1 1.3 1 0 0 1 1 1 0 Cell differentiation family, Rcd1-like Arm PF00514.23 OQS03758.1 - 0.019 15.0 0.2 0.27 11.3 0.0 2.6 2 0 0 2 2 2 0 Armadillo/beta-catenin-like repeat HEAT PF02985.22 OQS03758.1 - 0.15 12.4 0.9 26 5.4 0.0 3.5 4 0 0 4 4 4 0 HEAT repeat CS PF04969.16 OQS03760.1 - 9.3e-08 33.0 0.2 9.3e-08 33.0 0.2 1.4 2 0 0 2 2 2 1 CS domain DUF4843 PF16132.5 OQS03760.1 - 0.0031 17.1 0.4 0.004 16.8 0.4 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4843) PPTA PF01239.22 OQS03762.1 - 6.2e-25 86.1 12.3 2.5e-07 30.2 0.4 5.0 5 0 0 5 5 5 4 Protein prenyltransferase alpha subunit repeat MatE PF01554.18 OQS03763.1 - 4.7e-34 117.4 37.1 1.9e-19 69.9 16.2 2.3 2 0 0 2 2 2 2 MatE Iso_dh PF00180.20 OQS03765.1 - 9.9e-122 406.4 0.0 1.1e-121 406.2 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase MatE PF01554.18 OQS03766.1 - 1.9e-22 79.6 28.6 7.9e-12 45.1 10.0 2.3 2 0 0 2 2 2 2 MatE ABC_membrane PF00664.23 OQS03767.1 - 2.4e-63 214.4 1.5 3e-63 214.1 1.5 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region UPF0114 PF03350.16 OQS03767.1 - 0.011 15.9 0.1 0.033 14.4 0.1 1.8 1 0 0 1 1 1 0 Uncharacterized protein family, UPF0114 Sugar_tr PF00083.24 OQS03768.1 - 5.4e-42 144.2 32.1 1.9e-40 139.1 32.1 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OQS03768.1 - 1.2e-27 96.8 33.7 1.2e-20 73.7 10.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily HIG_1_N PF04588.13 OQS03768.1 - 7.5 6.9 8.3 0.78 10.0 0.6 3.1 2 0 0 2 2 2 0 Hypoxia induced protein conserved region Zn_Tnp_IS1595 PF12760.7 OQS03769.1 - 0.00078 19.4 1.1 0.12 12.4 0.1 2.4 2 0 0 2 2 2 1 Transposase zinc-ribbon domain TFIIS_C PF01096.18 OQS03769.1 - 0.00087 19.1 1.1 0.97 9.3 0.0 2.6 2 0 0 2 2 2 2 Transcription factor S-II (TFIIS) zf-LITAF-like PF10601.9 OQS03769.1 - 0.002 18.3 1.1 0.075 13.3 0.1 2.2 2 0 0 2 2 2 1 LITAF-like zinc ribbon domain Ogr_Delta PF04606.12 OQS03769.1 - 0.0027 17.6 3.6 0.19 11.8 0.1 2.3 2 0 0 2 2 2 1 Ogr/Delta-like zinc finger RNA_POL_M_15KD PF02150.16 OQS03769.1 - 0.0028 17.5 4.4 0.0093 15.8 0.1 2.7 2 1 1 3 3 3 1 RNA polymerases M/15 Kd subunit CpXC PF14353.6 OQS03769.1 - 0.0034 17.4 4.3 0.12 12.5 0.4 2.2 1 1 0 2 2 2 2 CpXC protein HypA PF01155.19 OQS03769.1 - 0.0043 17.0 0.3 0.0097 15.9 0.2 1.6 1 1 1 2 2 2 1 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Zn-ribbon_8 PF09723.10 OQS03769.1 - 0.0071 16.4 2.0 0.77 9.9 0.0 2.4 2 0 0 2 2 2 1 Zinc ribbon domain zf-ISL3 PF14690.6 OQS03769.1 - 0.016 15.9 1.1 1.1 9.9 0.1 2.4 2 0 0 2 2 2 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 zf-ribbon_3 PF13248.6 OQS03769.1 - 0.016 14.6 3.8 0.61 9.6 0.2 2.4 2 0 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_2 PF13240.6 OQS03769.1 - 0.018 14.7 4.2 0.52 10.1 0.1 2.5 2 0 0 2 2 2 0 zinc-ribbon domain MCM_OB PF17207.3 OQS03769.1 - 0.023 14.6 0.9 0.044 13.6 0.9 1.5 1 1 0 1 1 1 0 MCM OB domain zinc_ribbon_10 PF10058.9 OQS03769.1 - 0.027 14.2 2.5 0.88 9.3 0.0 2.9 3 1 0 3 3 2 0 Predicted integral membrane zinc-ribbon metal-binding protein DNA_RNApol_7kD PF03604.13 OQS03769.1 - 0.027 14.1 1.0 6.7 6.5 0.2 2.5 2 0 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit zf-RING_7 PF02591.15 OQS03769.1 - 0.038 14.2 0.9 2.5 8.4 0.2 2.6 2 0 0 2 2 2 0 C4-type zinc ribbon domain zinc_ribbon_4 PF13717.6 OQS03769.1 - 0.045 13.7 1.5 6.1 6.9 0.1 2.5 2 0 0 2 2 2 0 zinc-ribbon domain Sgf11 PF08209.11 OQS03769.1 - 0.047 13.3 1.2 5.3 6.7 0.2 2.5 2 0 0 2 2 2 0 Sgf11 (transcriptional regulation protein) DUF3268 PF11672.8 OQS03769.1 - 0.057 13.8 1.1 1.1 9.6 0.1 2.1 2 0 0 2 2 2 0 zinc-finger-containing domain zf-RRN7 PF11781.8 OQS03769.1 - 0.29 10.9 4.7 7.3 6.4 1.3 2.4 2 0 0 2 2 2 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 DNA_ligase_ZBD PF03119.16 OQS03769.1 - 0.61 10.2 5.9 18 5.4 5.9 2.5 1 1 0 1 1 1 0 NAD-dependent DNA ligase C4 zinc finger domain OrfB_Zn_ribbon PF07282.11 OQS03769.1 - 0.87 9.6 5.8 4.9 7.2 0.3 2.5 2 1 0 2 2 2 0 Putative transposase DNA-binding domain zf_UBZ PF18439.1 OQS03769.1 - 0.92 9.2 4.4 8.5 6.1 0.1 2.9 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger Rubredoxin_2 PF18073.1 OQS03769.1 - 2.1 8.1 8.8 3.7 7.4 0.7 3.1 3 0 0 3 3 3 0 Rubredoxin metal binding domain zf_CopZ PF18423.1 OQS03769.1 - 7.2 6.6 9.9 51 3.9 4.7 3.1 2 1 0 2 2 2 0 Zinc binding domain KBP_C PF12309.8 OQS03770.1 - 1.9e-51 175.7 0.6 5.5e-45 154.4 0.0 2.2 1 1 1 2 2 2 2 KIF-1 binding protein C terminal TPR_12 PF13424.6 OQS03770.1 - 4.3e-05 23.7 2.0 0.01 16.1 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 OQS03770.1 - 0.0085 16.1 2.1 1.4 9.1 0.4 3.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.17 OQS03770.1 - 0.028 14.5 1.2 14 6.1 0.1 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.28 OQS03770.1 - 0.14 12.1 0.5 7.3 6.6 0.2 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat Ank_2 PF12796.7 OQS03771.1 - 2.5e-77 255.5 53.0 1.7e-14 54.1 0.3 8.9 1 1 7 10 10 10 10 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQS03771.1 - 6.7e-58 192.4 17.4 1.3e-09 38.4 0.0 11.3 7 3 5 12 12 12 12 Ankyrin repeats (many copies) Ank_5 PF13857.6 OQS03771.1 - 5.6e-56 185.9 35.3 2.3e-09 37.3 0.2 10.1 5 1 3 9 9 9 9 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQS03771.1 - 5.4e-51 164.6 29.9 1.6e-05 24.9 0.1 15.7 15 1 1 16 16 16 11 Ankyrin repeat Ank PF00023.30 OQS03771.1 - 1.3e-38 129.8 48.4 8.7e-06 26.0 0.2 13.3 13 1 1 14 14 14 10 Ankyrin repeat IRK PF01007.20 OQS03771.1 - 0.11 12.3 6.3 0.058 13.2 3.0 2.2 2 0 0 2 2 2 0 Inward rectifier potassium channel transmembrane domain MCM PF00493.23 OQS03772.1 - 8.7e-98 325.9 0.0 1.3e-97 325.3 0.0 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 OQS03772.1 - 9.5e-37 125.7 0.0 1.8e-36 124.8 0.0 1.5 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 OQS03772.1 - 2.1e-22 79.4 3.8 3.2e-22 78.7 0.9 2.4 2 0 0 2 2 2 1 MCM AAA-lid domain MCM_N PF14551.6 OQS03772.1 - 1.3e-17 64.3 1.0 3.3e-17 63.0 0.3 2.1 2 0 0 2 2 2 1 MCM N-terminal domain MCM2_N PF12619.8 OQS03772.1 - 7.1e-12 45.9 27.2 7.1e-12 45.9 27.2 3.0 2 1 1 3 3 3 1 Mini-chromosome maintenance protein 2 Mg_chelatase PF01078.21 OQS03772.1 - 1.7e-09 37.4 0.1 5.3e-07 29.2 0.0 2.5 1 1 1 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 OQS03772.1 - 9.7e-06 25.6 0.0 3.4e-05 23.9 0.0 2.1 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 OQS03772.1 - 8.4e-05 22.4 0.1 0.0022 17.8 0.0 3.1 2 1 1 3 3 3 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 OQS03772.1 - 0.0093 15.7 0.0 0.09 12.5 0.0 2.2 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA PF00004.29 OQS03772.1 - 0.018 15.5 0.0 0.085 13.3 0.0 2.2 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 OQS03772.1 - 0.12 12.1 0.1 0.27 10.9 0.1 1.5 1 0 0 1 1 1 0 AAA domain Zn-ribbon_8 PF09723.10 OQS03772.1 - 0.16 12.1 0.7 0.38 10.9 0.7 1.6 1 0 0 1 1 1 0 Zinc ribbon domain Cytochrom_B_C PF00032.17 OQS03773.1 - 1.1 9.6 7.1 1 9.7 1.0 2.7 2 0 0 2 2 2 0 Cytochrome b(C-terminal)/b6/petD EamA PF00892.20 OQS03774.1 - 2.3e-22 79.6 43.1 7.9e-12 45.5 15.7 2.0 2 0 0 2 2 2 2 EamA-like transporter family Acyl_transf_3 PF01757.22 OQS03775.1 - 7.8e-24 84.4 35.6 7.8e-24 84.4 35.6 1.9 1 1 1 2 2 2 1 Acyltransferase family PAP_assoc PF03828.19 OQS03776.1 - 4.4e-14 52.4 0.0 8.9e-14 51.5 0.0 1.5 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 OQS03776.1 - 0.012 15.9 0.2 0.054 13.8 0.1 2.0 2 0 0 2 2 2 0 Nucleotidyltransferase domain Myb_DNA-bind_6 PF13921.6 OQS03777.1 - 6.7e-13 48.7 6.4 5.3e-10 39.4 0.6 3.7 1 1 1 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 OQS03777.1 - 6.8e-11 42.2 3.9 0.00015 21.9 0.1 4.5 5 0 0 5 5 5 3 Myb-like DNA-binding domain Sigma70_r4_2 PF08281.12 OQS03777.1 - 0.082 12.6 0.0 0.17 11.6 0.0 1.5 1 0 0 1 1 1 0 Sigma-70, region 4 p450 PF00067.22 OQS03778.1 - 1.5e-66 225.0 0.3 1.9e-66 224.7 0.3 1.0 1 0 0 1 1 1 1 Cytochrome P450 GDP_Man_Dehyd PF16363.5 OQS03779.1 - 0.0037 16.7 0.0 0.011 15.1 0.0 1.7 1 1 0 2 2 2 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 OQS03779.1 - 0.036 13.5 0.0 0.13 11.7 0.0 1.9 1 1 1 2 2 2 0 NAD dependent epimerase/dehydratase family Cnd1 PF12717.7 OQS03780.1 - 2.7e-07 30.8 0.5 0.023 14.8 0.0 2.3 1 1 1 2 2 2 2 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 OQS03780.1 - 9.8e-05 21.1 0.2 0.00025 19.8 0.1 1.6 1 1 0 1 1 1 1 Adaptin N terminal region 4HB PF17947.1 OQS03780.1 - 0.0005 20.1 0.1 0.0025 17.9 0.0 2.2 2 0 0 2 2 2 1 Four helical bundle domain P16-Arc PF04699.14 OQS03780.1 - 0.00071 20.1 0.1 4 7.9 0.2 3.4 3 0 0 3 3 3 2 ARP2/3 complex 16 kDa subunit (p16-Arc) HEAT_2 PF13646.6 OQS03780.1 - 0.0035 17.7 9.3 0.16 12.4 0.4 4.2 2 2 1 4 4 4 1 HEAT repeats HEAT_EZ PF13513.6 OQS03780.1 - 0.011 16.2 7.6 8.7 7.0 0.7 5.2 5 0 0 5 5 5 0 HEAT-like repeat CLASP_N PF12348.8 OQS03780.1 - 0.026 14.1 0.0 1.7 8.2 0.0 2.6 1 1 1 2 2 2 0 CLASP N terminal MMS19_N PF14500.6 OQS03780.1 - 0.049 13.2 0.0 7.4 6.1 0.0 3.0 1 1 2 3 3 3 0 Dos2-interacting transcription regulator of RNA-Pol-II Vac14_Fab1_bd PF12755.7 OQS03780.1 - 0.14 12.8 0.1 8.5 7.1 0.0 3.2 3 1 0 3 3 3 0 Vacuolar 14 Fab1-binding region PH PF00169.29 OQS03781.1 - 1.6e-45 153.9 9.6 1e-14 54.9 0.9 4.6 5 0 0 5 5 5 4 PH domain PH_8 PF15409.6 OQS03781.1 - 1.5e-13 50.8 3.6 6.1e-05 23.2 0.0 4.4 5 0 0 5 5 5 3 Pleckstrin homology domain PH_11 PF15413.6 OQS03781.1 - 2.6e-08 34.2 15.9 0.0027 18.1 4.5 6.1 4 2 1 5 5 5 3 Pleckstrin homology domain PH_3 PF14593.6 OQS03781.1 - 2.4e-06 27.6 3.9 3.5e-05 23.8 0.2 3.3 4 0 0 4 4 4 1 PH domain PH_9 PF15410.6 OQS03781.1 - 0.00054 20.3 2.2 0.11 12.9 0.2 4.2 4 1 0 4 4 4 1 Pleckstrin homology domain Mcp5_PH PF12814.7 OQS03781.1 - 0.038 14.1 0.3 14 5.8 0.0 2.5 2 0 0 2 2 2 0 Meiotic cell cortex C-terminal pleckstrin homology Sec61_beta PF03911.16 OQS03781.1 - 0.14 12.3 1.4 50 4.0 0.1 3.9 4 0 0 4 4 4 0 Sec61beta family SPOR PF05036.13 OQS03782.1 - 0.016 15.6 0.1 0.029 14.8 0.1 1.3 1 0 0 1 1 1 0 Sporulation related domain DOMON PF03351.17 OQS03783.1 - 1.9e-07 31.3 0.2 2.4e-07 31.0 0.2 1.1 1 0 0 1 1 1 1 DOMON domain BT1 PF03092.16 OQS03784.1 - 8.9e-32 110.0 17.1 5e-16 58.0 5.2 2.1 2 0 0 2 2 2 2 BT1 family MAPEG PF01124.18 OQS03784.1 - 0.0088 15.9 0.3 0.03 14.2 0.3 2.0 1 0 0 1 1 1 1 MAPEG family Phage_holin_1 PF04531.13 OQS03784.1 - 0.92 10.1 3.8 3 8.4 0.0 3.1 3 0 0 3 3 3 0 Bacteriophage holin BT1 PF03092.16 OQS03785.1 - 9.9e-14 50.5 11.0 4.1e-09 35.2 0.2 3.4 4 0 0 4 4 4 3 BT1 family RCC1 PF00415.18 OQS03786.1 - 1.8e-32 111.7 16.1 1.2e-12 48.3 0.5 6.8 8 1 0 8 8 8 4 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 OQS03786.1 - 2.8e-29 100.2 18.9 2.3e-07 30.4 0.0 6.6 7 0 0 7 7 7 5 Regulator of chromosome condensation (RCC1) repeat Kelch_4 PF13418.6 OQS03786.1 - 0.49 10.4 6.4 19 5.4 0.2 4.1 4 0 0 4 4 4 0 Galactose oxidase, central domain Beach PF02138.18 OQS03787.1 - 9.7e-96 320.4 3.6 3.9e-95 318.4 0.0 3.2 2 1 0 2 2 2 1 Beige/BEACH domain Asparaginase_2 PF01112.18 OQS03787.1 - 6.8e-34 117.3 7.1 6.8e-34 117.3 7.1 2.5 2 1 0 2 2 1 1 Asparaginase DUF4704 PF15787.5 OQS03787.1 - 5.2e-33 114.5 0.1 5.2e-33 114.5 0.1 2.9 3 0 0 3 3 3 1 Domain of unknown function (DUF4704) Ion_trans PF00520.31 OQS03787.1 - 2.3e-21 76.2 17.9 5.7e-21 74.8 17.9 1.7 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 OQS03787.1 - 3.3e-12 46.2 0.8 3.3e-12 46.2 0.8 2.3 2 0 0 2 2 2 1 Ion channel WD40 PF00400.32 OQS03787.1 - 4.5e-11 43.1 8.6 3.1e-05 24.7 0.4 4.8 4 0 0 4 4 4 2 WD domain, G-beta repeat PH_BEACH PF14844.6 OQS03787.1 - 1.5e-08 34.7 0.4 7.6e-08 32.4 0.4 2.4 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH cNMP_binding PF00027.29 OQS03787.1 - 0.0014 18.7 0.0 0.0044 17.0 0.0 1.9 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain ANAPC4_WD40 PF12894.7 OQS03787.1 - 0.006 16.9 0.0 42 4.5 0.0 4.1 3 1 0 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain Laminin_G_3 PF13385.6 OQS03787.1 - 0.022 14.9 0.0 0.065 13.4 0.0 1.8 1 0 0 1 1 1 0 Concanavalin A-like lectin/glucanases superfamily MRP-S28 PF10213.9 OQS03787.1 - 0.14 12.6 4.1 0.15 12.5 0.0 2.8 3 0 0 3 3 2 0 Mitochondrial ribosomal subunit protein MscS_porin PF12795.7 OQS03787.1 - 1.7 8.2 59.8 1.6 8.2 39.9 3.3 1 1 2 3 3 3 0 Mechanosensitive ion channel porin domain Pkinase PF00069.25 OQS03789.1 - 3e-61 207.1 0.0 3.8e-61 206.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQS03789.1 - 3.8e-33 114.9 0.0 4.9e-33 114.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OQS03789.1 - 0.17 11.2 0.0 0.29 10.4 0.0 1.3 1 0 0 1 1 1 0 Kinase-like HIRA_B PF09453.10 OQS03790.1 - 0.004 17.0 0.8 0.0094 15.8 0.8 1.7 1 0 0 1 1 1 1 HIRA B motif DHFR_1 PF00186.19 OQS03791.1 - 1.1e-36 125.9 0.0 1.3e-36 125.8 0.0 1.0 1 0 0 1 1 1 1 Dihydrofolate reductase DUF4240 PF14024.6 OQS03791.1 - 0.12 12.5 0.0 0.17 12.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4240) Glutaredoxin PF00462.24 OQS03792.1 - 8e-28 96.4 0.0 9.4e-16 57.8 0.0 2.4 2 0 0 2 2 2 2 Glutaredoxin Pro_isomerase PF00160.21 OQS03792.1 - 1.5e-22 80.6 0.0 2.6e-22 79.8 0.0 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Thioredoxin_2 PF13098.6 OQS03792.1 - 4e-05 24.0 0.2 0.00071 20.0 0.1 2.7 2 1 1 3 3 3 1 Thioredoxin-like domain DUF836 PF05768.14 OQS03792.1 - 0.00032 21.0 0.0 0.00064 20.1 0.0 1.5 1 0 0 1 1 1 1 Glutaredoxin-like domain (DUF836) TraF PF13728.6 OQS03792.1 - 0.0079 16.0 0.0 0.02 14.7 0.0 1.6 2 0 0 2 2 2 1 F plasmid transfer operon protein Thioredoxin_4 PF13462.6 OQS03792.1 - 0.022 14.9 0.7 1.3 9.1 0.1 3.1 3 1 1 4 4 4 0 Thioredoxin Thioredoxin_3 PF13192.6 OQS03792.1 - 0.031 14.3 0.0 0.096 12.8 0.0 1.8 1 0 0 1 1 1 0 Thioredoxin domain CATSPERG PF15064.6 OQS03792.1 - 0.033 12.0 0.0 0.049 11.5 0.0 1.1 1 0 0 1 1 1 0 Cation channel sperm-associated protein subunit gamma GST_N_3 PF13417.6 OQS03792.1 - 0.1 13.0 0.0 0.34 11.4 0.0 1.9 2 0 0 2 2 2 0 Glutathione S-transferase, N-terminal domain eIF3_subunit PF08597.10 OQS03793.1 - 0.091 12.7 11.3 0.14 12.1 11.3 1.2 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit FAM222A PF15258.6 OQS03793.1 - 0.14 11.3 14.4 0.016 14.4 10.1 1.5 2 0 0 2 2 2 0 Protein family of FAM222A AAA_23 PF13476.6 OQS03793.1 - 2 8.8 19.9 2.6 8.5 19.9 1.2 1 0 0 1 1 1 0 AAA domain GAGA_bind PF06217.12 OQS03793.1 - 2.9 8.1 13.4 4 7.7 12.8 1.3 1 1 0 1 1 1 0 GAGA binding protein-like family Ammonium_transp PF00909.21 OQS03794.1 - 7e-97 324.6 31.1 8.1e-97 324.4 31.1 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family TetR_C_2 PF08361.11 OQS03795.1 - 0.07 13.3 0.0 0.11 12.6 0.0 1.3 1 0 0 1 1 1 0 MAATS-type transcriptional repressor, C-terminal region Phage_integrase PF00589.22 OQS03795.1 - 0.11 12.3 0.0 0.21 11.4 0.0 1.6 1 1 0 1 1 1 0 Phage integrase family Ion_trans PF00520.31 OQS03796.1 - 3.9e-171 566.6 68.5 2.1e-46 158.1 0.2 4.3 4 1 0 4 4 4 4 Ion transport protein GPHH PF16905.5 OQS03796.1 - 1e-07 31.6 0.0 2.4e-07 30.4 0.0 1.7 1 0 0 1 1 1 1 Voltage-dependent L-type calcium channel, IQ-associated PKD_channel PF08016.12 OQS03796.1 - 5.3e-05 22.1 76.5 0.00028 19.7 1.0 10.2 8 3 2 10 10 10 8 Polycystin cation channel MgtE PF01769.16 OQS03796.1 - 0.038 14.4 0.1 0.038 14.4 0.1 8.3 8 3 1 9 9 9 0 Divalent cation transporter Calx-beta PF03160.14 OQS03797.1 - 1.2e-13 51.1 0.0 0.00086 19.4 0.0 4.1 4 0 0 4 4 4 3 Calx-beta domain TNFR_c6 PF00020.18 OQS03797.1 - 7.3e-05 23.1 13.1 7.3e-05 23.1 13.1 3.1 2 1 1 3 3 3 2 TNFR/NGFR cysteine-rich region Chlorovi_GP_rpt PF06598.11 OQS03797.1 - 3.9 7.6 14.8 1.4 9.0 1.5 4.6 4 0 0 4 4 4 0 Chlorovirus glycoprotein repeat PH PF00169.29 OQS03798.1 - 0.00014 22.4 0.0 0.00032 21.2 0.0 1.6 1 1 0 1 1 1 1 PH domain RAB3GAP2_N PF14655.6 OQS03798.1 - 0.024 13.9 0.0 0.029 13.6 0.0 1.1 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus PEX11 PF05648.14 OQS03799.1 - 3.9e-15 55.9 0.1 4.4e-15 55.7 0.1 1.0 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) Ank_2 PF12796.7 OQS03800.1 - 2e-13 50.7 0.9 1.4e-10 41.6 0.1 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OQS03800.1 - 3.4e-11 42.3 1.7 0.00033 20.9 0.0 4.0 4 0 0 4 4 4 3 Ankyrin repeat Ank_4 PF13637.6 OQS03800.1 - 1.3e-10 41.6 0.5 3.3e-06 27.5 0.0 2.7 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 OQS03800.1 - 6.5e-09 35.8 1.6 0.0082 16.6 0.0 4.1 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.6 OQS03800.1 - 9.1e-09 35.4 1.4 0.0047 17.2 0.0 3.4 3 1 0 3 3 3 2 Ankyrin repeats (many copies) SAM_2 PF07647.17 OQS03801.1 - 2.7e-11 43.4 0.0 1e-10 41.6 0.0 2.0 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 OQS03801.1 - 7e-11 42.4 0.0 1.2e-10 41.6 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) zf-C2HC_2 PF13913.6 OQS03801.1 - 0.014 15.3 47.0 0.14 12.1 0.0 8.5 9 0 0 9 9 9 0 zinc-finger of a C2HC-type SAM_PNT PF02198.16 OQS03801.1 - 0.02 14.9 0.0 0.048 13.6 0.0 1.6 1 0 0 1 1 1 0 Sterile alpha motif (SAM)/Pointed domain CENP-B_dimeris PF09026.10 OQS03801.1 - 0.021 15.2 13.3 0.25 11.8 3.1 2.3 2 0 0 2 2 2 0 Centromere protein B dimerisation domain p450 PF00067.22 OQS03802.1 - 8.7e-163 542.3 0.1 5.5e-82 276.0 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 TetR_C_28 PF17937.1 OQS03802.1 - 0.00062 20.2 0.3 0.59 10.6 0.0 2.5 2 0 0 2 2 2 2 Tetracyclin repressor-like, C-terminal domain CH PF00307.31 OQS03804.1 - 3.5e-45 152.7 0.5 3e-22 78.9 0.0 2.1 2 0 0 2 2 2 2 Calponin homology (CH) domain CAMSAP_CH PF11971.8 OQS03804.1 - 4.4e-12 45.7 0.5 7.5e-08 32.1 0.1 2.4 2 0 0 2 2 2 2 CAMSAP CH domain CH_2 PF06294.11 OQS03804.1 - 0.002 18.2 0.0 0.21 11.7 0.0 2.3 2 0 0 2 2 2 2 CH-like domain in sperm protein CH PF00307.31 OQS03805.1 - 1e-43 147.9 4.2 3e-22 78.8 0.2 3.7 4 0 0 4 4 4 2 Calponin homology (CH) domain CAMSAP_CH PF11971.8 OQS03805.1 - 1.6e-10 40.7 0.1 4.4e-05 23.2 0.0 3.3 3 0 0 3 3 3 2 CAMSAP CH domain CH_2 PF06294.11 OQS03805.1 - 0.0028 17.7 0.6 0.92 9.7 0.0 3.3 3 0 0 3 3 3 1 CH-like domain in sperm protein Spectrin PF00435.21 OQS03805.1 - 0.026 15.0 14.0 0.57 10.7 0.1 4.5 4 0 0 4 4 4 0 Spectrin repeat Minor_capsid_3 PF12691.7 OQS03805.1 - 0.054 13.9 2.6 0.35 11.3 0.2 3.1 4 0 0 4 4 4 0 Minor capsid protein from bacteriophage CutA1 PF03091.15 OQS03805.1 - 0.11 12.3 1.7 0.39 10.6 0.3 2.4 1 1 1 2 2 2 0 CutA1 divalent ion tolerance protein DUF2120 PF09893.9 OQS03805.1 - 1.4 9.0 5.5 1.3 9.2 2.9 2.2 1 1 1 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2120) T3SS_needle_F PF09392.10 OQS03805.1 - 1.6 9.0 6.1 2.1 8.6 0.5 3.4 3 0 0 3 3 3 0 Type III secretion needle MxiH, YscF, SsaG, EprI, PscF, EscF 4HB_MCP_1 PF12729.7 OQS03805.1 - 5.8 6.4 14.4 0.15 11.6 0.8 3.1 2 1 1 3 3 3 0 Four helix bundle sensory module for signal transduction Pho88 PF10032.9 OQS03806.1 - 1.8e-29 102.3 0.0 2.2e-29 102.0 0.0 1.0 1 0 0 1 1 1 1 Phosphate transport (Pho88) Dimerisation PF08100.11 OQS03807.1 - 0.064 13.3 0.4 0.15 12.1 0.1 1.8 2 0 0 2 2 2 0 Dimerisation domain zf-UBR PF02207.20 OQS03808.1 - 2e-18 66.3 16.2 2e-18 66.3 16.2 3.0 2 0 0 2 2 2 1 Putative zinc finger in N-recognin (UBR box) Tub_N PF16322.5 OQS03808.1 - 0.045 14.2 0.3 0.078 13.4 0.3 1.3 1 0 0 1 1 1 0 Tubby N-terminal Drf_DAD PF06345.11 OQS03808.1 - 0.064 13.3 0.2 0.17 12.0 0.2 1.8 1 0 0 1 1 1 0 DRF Autoregulatory Domain ClpS PF02617.17 OQS03808.1 - 0.15 11.8 0.0 0.44 10.4 0.0 1.8 1 0 0 1 1 1 0 ATP-dependent Clp protease adaptor protein ClpS CNDH2_C PF16858.5 OQS03808.1 - 1.4 8.7 5.1 2.3 8.0 5.1 1.2 1 0 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term HECT PF00632.25 OQS03811.1 - 3e-72 243.7 0.0 4.5e-72 243.1 0.0 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) zf-RanBP PF00641.18 OQS03811.1 - 0.0055 16.0 2.6 0.011 15.0 2.6 1.5 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others FdhE PF04216.12 OQS03811.1 - 0.49 10.2 2.1 0.92 9.3 2.1 1.4 1 0 0 1 1 1 0 Protein involved in formate dehydrogenase formation Vps36-NZF-N PF16988.5 OQS03811.1 - 1.3 8.5 3.7 5.4 6.5 3.7 1.9 1 1 0 1 1 1 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain Peptidase_S8 PF00082.22 OQS03812.1 - 2.6e-35 122.1 3.7 3.4e-35 121.7 3.7 1.2 1 0 0 1 1 1 1 Subtilase family PIP5K PF01504.18 OQS03813.1 - 3.7e-66 223.1 0.0 5.7e-66 222.5 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase Dicty_CAR PF05462.11 OQS03813.1 - 2.4e-07 30.2 6.4 2.4e-07 30.2 6.4 1.5 1 1 0 1 1 1 1 Slime mold cyclic AMP receptor 7tm_2 PF00002.24 OQS03813.1 - 2.1e-05 23.9 12.5 4.8e-05 22.8 12.3 1.7 1 1 0 1 1 1 1 7 transmembrane receptor (Secretin family) 7tm_1 PF00001.21 OQS03813.1 - 0.013 14.9 7.7 0.03 13.6 7.4 1.9 1 1 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 OQS03813.1 - 2.5 7.4 17.1 0.12 11.7 11.6 1.7 2 0 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srsx Aminotran_4 PF01063.19 OQS03814.1 - 2.1e-20 73.5 0.0 1.2e-19 71.0 0.0 1.9 1 1 0 1 1 1 1 Amino-transferase class IV IQ PF00612.27 OQS03815.1 - 0.022 14.5 0.2 0.022 14.5 0.2 4.3 4 0 0 4 4 4 0 IQ calmodulin-binding motif WW PF00397.26 OQS03815.1 - 0.041 14.0 3.1 0.092 12.9 3.1 1.6 1 0 0 1 1 1 0 WW domain DUF92 PF01940.16 OQS03816.1 - 1.2e-73 247.5 2.9 1.4e-73 247.2 2.9 1.0 1 0 0 1 1 1 1 Integral membrane protein DUF92 CCDC53 PF10152.9 OQS03817.1 - 3.9e-32 111.8 24.4 1.4e-12 48.3 0.6 4.3 3 1 1 4 4 4 3 Subunit CCDC53 of WASH complex zf-MYND PF01753.18 OQS03817.1 - 1.7e-06 28.0 14.8 2.6e-06 27.4 14.8 1.3 1 0 0 1 1 1 1 MYND finger Spc7 PF08317.11 OQS03817.1 - 0.0035 16.3 3.0 0.0035 16.3 3.0 1.4 2 0 0 2 2 2 1 Spc7 kinetochore protein PI3K_1B_p101 PF10486.9 OQS03817.1 - 0.0071 14.2 3.7 0.01 13.7 3.7 1.1 1 0 0 1 1 1 1 Phosphoinositide 3-kinase gamma adapter protein p101 subunit DUF2052 PF09747.9 OQS03817.1 - 0.095 12.8 7.4 0.15 12.2 7.4 1.2 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) DivIC PF04977.15 OQS03817.1 - 0.54 10.1 7.3 0.098 12.4 2.7 2.1 2 0 0 2 2 2 0 Septum formation initiator zf-C6H2 PF15801.5 OQS03817.1 - 1 9.7 11.2 1.9 8.9 11.2 1.4 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding PBP1_TM PF14812.6 OQS03817.1 - 3 8.3 6.9 6 7.3 6.9 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Ank_2 PF12796.7 OQS03818.1 - 1.3e-63 211.5 43.4 4.4e-18 65.7 0.7 4.5 1 1 5 6 6 6 6 Ankyrin repeats (3 copies) Ank PF00023.30 OQS03818.1 - 6.7e-49 162.3 34.7 2.4e-08 34.1 0.1 8.2 8 0 0 8 8 8 8 Ankyrin repeat Ank_3 PF13606.6 OQS03818.1 - 6.7e-36 118.2 12.6 0.00016 21.8 0.0 8.2 8 0 0 8 8 8 6 Ankyrin repeat Ank_4 PF13637.6 OQS03818.1 - 5.8e-32 109.6 13.0 8.8e-10 38.9 0.1 5.9 3 1 3 6 6 6 6 Ankyrin repeats (many copies) Ank_5 PF13857.6 OQS03818.1 - 1.4e-28 98.6 18.1 3.7e-07 30.3 1.4 5.4 3 1 2 5 5 5 5 Ankyrin repeats (many copies) HEM4 PF02602.15 OQS03818.1 - 0.0022 17.4 0.1 0.23 10.8 0.0 2.8 2 1 1 3 3 3 1 Uroporphyrinogen-III synthase HemD Rac1 PF09632.10 OQS03818.1 - 0.19 10.9 2.4 2.8 7.0 0.4 2.3 2 0 0 2 2 2 0 Rac1-binding domain NVEALA PF14055.6 OQS03818.1 - 0.3 11.1 9.6 10 6.2 0.1 4.8 5 0 0 5 5 5 0 NVEALA protein CARM1 PF11531.8 OQS03818.1 - 0.62 10.3 2.7 8.9 6.5 0.1 3.2 2 1 0 3 3 3 0 Coactivator-associated arginine methyltransferase 1 N terminal Arg_repressor PF01316.21 OQS03818.1 - 0.98 9.2 5.1 39 4.1 0.0 4.5 6 0 0 6 6 6 0 Arginine repressor, DNA binding domain DUF2520 PF10728.9 OQS03818.1 - 2.4 7.9 12.6 0.9 9.3 0.9 3.6 1 1 3 4 4 4 0 Domain of unknown function (DUF2520) EamA PF00892.20 OQS03819.1 - 2.5e-21 76.3 44.3 5.9e-16 58.9 18.7 2.1 2 0 0 2 2 2 2 EamA-like transporter family TPT PF03151.16 OQS03819.1 - 0.0017 17.8 11.2 0.0023 17.3 10.3 1.8 1 1 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 OQS03820.1 - 1e-11 45.2 35.6 4.1e-09 36.7 12.2 2.1 2 0 0 2 2 2 2 EamA-like transporter family DUF2651 PF10852.8 OQS03820.1 - 0.016 15.8 2.9 0.016 15.8 2.9 4.1 3 2 0 3 3 3 0 Protein of unknown function (DUF2651) Tim44 PF04280.15 OQS03821.1 - 6.5e-06 26.3 0.0 0.0012 19.0 0.0 2.8 3 0 0 3 3 3 2 Tim44-like domain Mito_carr PF00153.27 OQS03822.1 - 2.2e-55 184.6 8.1 1.9e-20 72.6 0.0 4.0 3 1 0 3 3 3 3 Mitochondrial carrier protein FGase PF05013.12 OQS03822.1 - 1.4e-11 45.0 0.0 3.2e-05 24.3 0.0 2.7 2 1 1 3 3 3 2 N-formylglutamate amidohydrolase Serine_protease PF18405.1 OQS03822.1 - 0.027 13.6 0.9 0.35 10.0 0.2 2.3 1 1 1 2 2 2 0 Gammaproteobacterial serine protease Tim44 PF04280.15 OQS03823.1 - 0.0013 18.9 0.2 0.11 12.6 0.2 2.1 1 1 0 1 1 1 1 Tim44-like domain Mo25 PF08569.11 OQS03824.1 - 4e-60 203.9 4.3 5e-60 203.6 4.3 1.0 1 0 0 1 1 1 1 Mo25-like ASH PF15780.5 OQS03825.1 - 8.4e-36 122.1 0.1 3.3e-05 24.0 0.0 10.0 9 0 0 9 9 9 9 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin Motile_Sperm PF00635.26 OQS03825.1 - 4.2e-15 55.5 0.1 0.23 11.3 0.0 7.7 8 0 0 8 8 8 4 MSP (Major sperm protein) domain MYCBPAP PF14646.6 OQS03825.1 - 0.0015 17.5 0.0 3.7 6.4 0.0 4.0 4 1 1 5 5 5 2 MYCBP-associated protein family Tim44 PF04280.15 OQS03826.1 - 0.00047 20.3 0.0 0.021 14.9 0.0 2.3 2 0 0 2 2 2 2 Tim44-like domain DUF3228 PF11539.8 OQS03827.1 - 1.2e-77 259.8 0.0 1.4e-77 259.7 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3228) Ank_2 PF12796.7 OQS03828.1 - 2.2e-44 149.9 9.8 4.4e-13 49.6 0.8 6.5 5 1 1 6 6 6 6 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OQS03828.1 - 1.5e-26 89.5 5.9 0.0076 16.7 0.0 11.1 11 0 0 11 11 11 5 Ankyrin repeat Ank PF00023.30 OQS03828.1 - 2.9e-26 90.7 8.5 0.00073 19.9 0.0 9.2 9 0 0 9 9 9 6 Ankyrin repeat Ank_4 PF13637.6 OQS03828.1 - 3.6e-23 81.6 6.4 1.2e-05 25.8 0.0 8.1 6 2 2 8 8 8 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 OQS03828.1 - 7.1e-22 77.2 7.4 0.00011 22.4 0.0 7.6 4 2 4 8 8 8 6 Ankyrin repeats (many copies) CHAD PF05235.14 OQS03828.1 - 0.11 12.4 1.7 0.13 12.2 0.1 1.9 2 0 0 2 2 2 0 CHAD domain CytochromB561_N PF09786.9 OQS03829.1 - 3.7e-33 115.4 0.0 5.3e-33 114.9 0.0 1.2 1 0 0 1 1 1 1 Cytochrome B561, N terminal ABC_tran PF00005.27 OQS03831.1 - 5.3e-28 98.2 0.1 7.9e-28 97.7 0.1 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 OQS03831.1 - 2e-12 47.6 0.4 6.5e-06 26.2 0.0 2.2 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 OQS03831.1 - 8.2e-06 25.4 0.1 3.9e-05 23.2 0.1 2.0 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_25 PF13481.6 OQS03831.1 - 6.9e-05 22.5 0.0 9.9e-05 22.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 OQS03831.1 - 9.1e-05 22.1 0.4 0.00025 20.7 0.3 1.8 1 1 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.6 OQS03831.1 - 0.00015 22.2 0.0 0.00023 21.6 0.0 1.5 2 0 0 2 2 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 OQS03831.1 - 0.00075 19.4 0.0 0.0012 18.8 0.0 1.3 1 0 0 1 1 1 1 RsgA GTPase Thymidylate_kin PF02223.17 OQS03831.1 - 0.00094 18.9 0.1 0.97 9.1 0.0 2.3 2 0 0 2 2 2 2 Thymidylate kinase AAA_23 PF13476.6 OQS03831.1 - 0.0011 19.5 0.0 0.002 18.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 OQS03831.1 - 0.002 18.4 0.0 0.0043 17.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_13 PF13166.6 OQS03831.1 - 0.0043 15.8 0.1 0.15 10.7 0.0 2.0 2 0 0 2 2 2 1 AAA domain NTPase_1 PF03266.15 OQS03831.1 - 0.0061 16.5 0.0 0.17 11.8 0.0 2.2 1 1 1 2 2 2 1 NTPase AAA_18 PF13238.6 OQS03831.1 - 0.0067 17.0 0.0 0.013 16.0 0.0 1.5 1 1 0 1 1 1 1 AAA domain NACHT PF05729.12 OQS03831.1 - 0.007 16.3 0.0 0.015 15.3 0.0 1.6 1 0 0 1 1 1 1 NACHT domain Rad17 PF03215.15 OQS03831.1 - 0.011 15.7 0.0 0.018 14.9 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_28 PF13521.6 OQS03831.1 - 0.023 15.0 0.0 0.031 14.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 OQS03831.1 - 0.031 14.0 0.1 0.05 13.3 0.2 1.5 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 OQS03831.1 - 0.044 14.2 0.0 0.21 12.0 0.0 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Cytidylate_kin PF02224.18 OQS03831.1 - 0.06 13.1 0.0 0.096 12.4 0.0 1.4 1 0 0 1 1 1 0 Cytidylate kinase AAA_24 PF13479.6 OQS03831.1 - 0.064 13.0 0.0 0.18 11.5 0.0 1.7 2 0 0 2 2 2 0 AAA domain T2SSE PF00437.20 OQS03831.1 - 0.066 12.3 0.0 0.12 11.4 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_33 PF13671.6 OQS03831.1 - 0.09 12.9 0.0 0.21 11.7 0.0 1.7 2 0 0 2 2 2 0 AAA domain cobW PF02492.19 OQS03831.1 - 0.11 12.1 0.1 0.17 11.4 0.1 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain ATPase_2 PF01637.18 OQS03831.1 - 0.12 12.2 0.0 0.18 11.7 0.0 1.2 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea Roc PF08477.13 OQS03831.1 - 0.16 12.2 0.0 0.32 11.2 0.0 1.5 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase ABC_ATPase PF09818.9 OQS03831.1 - 0.17 10.6 0.8 2.4 6.9 0.2 2.1 2 0 0 2 2 2 0 Predicted ATPase of the ABC class Aminotran_5 PF00266.19 OQS03832.1 - 2e-37 129.0 0.0 4.4e-26 91.7 0.0 2.2 2 0 0 2 2 2 2 Aminotransferase class-V Aminotran_1_2 PF00155.21 OQS03832.1 - 0.00035 19.9 0.0 0.00067 18.9 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class I and II PAP2 PF01569.21 OQS03833.1 - 6.1e-26 90.8 3.9 6.1e-26 90.8 3.9 1.7 2 1 0 2 2 2 1 PAP2 superfamily PAP2_3 PF14378.6 OQS03833.1 - 0.00063 19.5 6.9 0.25 11.0 1.9 2.7 2 1 1 3 3 3 2 PAP2 superfamily MTABC_N PF16185.5 OQS03833.1 - 1 8.8 5.4 0.71 9.3 0.1 2.6 3 0 0 3 3 3 0 Mitochondrial ABC-transporter N-terminal five TM region Exo_endo_phos PF03372.23 OQS03834.1 - 1e-14 54.7 0.0 1.9e-14 53.8 0.0 1.5 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family BILBO1_N PF18281.1 OQS03834.1 - 0.085 13.3 0.0 0.16 12.4 0.0 1.4 1 0 0 1 1 1 0 BILBO1 N-terminal domain Cupin_4 PF08007.12 OQS03835.1 - 1.2e-14 54.5 4.0 6.4e-14 52.1 4.0 2.0 1 1 0 1 1 1 1 Cupin superfamily protein Cupin_8 PF13621.6 OQS03835.1 - 1.1e-13 51.5 0.4 2.8e-13 50.2 0.0 1.7 2 0 0 2 2 2 1 Cupin-like domain JmjC PF02373.22 OQS03835.1 - 0.0017 18.8 1.5 0.0078 16.6 0.2 2.6 2 1 1 3 3 3 1 JmjC domain, hydroxylase Cupin_2 PF07883.11 OQS03835.1 - 0.0026 17.5 0.0 0.0065 16.2 0.0 1.6 1 0 0 1 1 1 1 Cupin domain DNA_pol_phi PF04931.13 OQS03835.1 - 0.54 8.3 8.1 0.76 7.8 8.1 1.2 1 0 0 1 1 1 0 DNA polymerase phi DUF2722 PF10846.8 OQS03835.1 - 0.65 8.9 2.7 0.9 8.4 2.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) zf-RING_2 PF13639.6 OQS03836.1 - 1.4e-10 41.3 6.0 4e-10 39.9 6.0 1.8 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 OQS03836.1 - 4.3e-07 30.1 3.3 1.3e-06 28.6 3.3 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_11 PF17123.5 OQS03836.1 - 6.5e-07 29.0 2.2 6.5e-07 29.0 2.2 2.4 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 OQS03836.1 - 5e-06 26.3 4.5 5e-06 26.3 4.5 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OQS03836.1 - 1.7e-05 24.6 3.2 4.1e-05 23.5 3.2 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 OQS03836.1 - 0.00028 20.7 4.3 0.00054 19.8 4.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 OQS03836.1 - 0.001 18.8 2.8 0.0023 17.8 2.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_1 PF14446.6 OQS03836.1 - 0.032 14.2 2.8 0.22 11.5 0.7 2.3 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 Prok-RING_4 PF14447.6 OQS03836.1 - 0.065 13.1 4.0 0.12 12.3 4.0 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 OQS03836.1 - 0.12 12.4 0.9 0.34 11.0 0.9 1.8 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_ribbon_17 PF17120.5 OQS03836.1 - 0.25 11.0 2.2 0.61 9.7 2.2 1.6 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-RING_UBOX PF13445.6 OQS03836.1 - 0.46 10.6 3.8 0.33 11.0 1.7 1.9 1 1 0 1 1 1 0 RING-type zinc-finger DUF445 PF04286.12 OQS03838.1 - 3.5e-14 53.4 2.9 6.6e-09 36.0 0.0 2.7 2 1 0 2 2 2 2 Protein of unknown function (DUF445) SAM_PNT PF02198.16 OQS03838.1 - 0.00077 19.4 0.1 0.0026 17.7 0.0 1.9 2 0 0 2 2 2 1 Sterile alpha motif (SAM)/Pointed domain Lact-deh-memb PF09330.11 OQS03838.1 - 0.079 12.3 0.2 0.16 11.3 0.2 1.4 1 0 0 1 1 1 0 D-lactate dehydrogenase, membrane binding EF-hand_7 PF13499.6 OQS03839.1 - 1.9e-14 53.9 9.8 0.11 13.0 0.3 8.5 9 0 0 9 9 9 4 EF-hand domain pair EF-hand_1 PF00036.32 OQS03839.1 - 1.2e-08 33.8 0.2 1.3 8.7 0.1 7.3 7 0 0 7 7 7 2 EF hand EF-hand_6 PF13405.6 OQS03839.1 - 5.4e-07 29.0 3.4 0.98 9.5 0.4 7.6 9 0 0 9 9 9 1 EF-hand domain EF-hand_8 PF13833.6 OQS03839.1 - 2.3e-06 27.3 0.1 8.2 6.4 0.0 7.3 8 0 0 8 8 8 2 EF-hand domain pair C2 PF00168.30 OQS03839.1 - 0.0046 17.2 0.0 0.01 16.1 0.0 1.6 1 0 0 1 1 1 1 C2 domain CDT1 PF08839.11 OQS03839.1 - 0.052 13.8 2.4 0.14 12.5 2.4 1.7 1 0 0 1 1 1 0 DNA replication factor CDT1 like HA PF03457.14 OQS03839.1 - 0.13 12.6 0.0 25 5.3 0.0 3.5 3 0 0 3 3 3 0 Helicase associated domain DRIM PF07539.12 OQS03841.1 - 1.8e-110 370.2 6.9 1.8e-110 370.2 6.9 3.9 4 1 0 4 4 4 2 Down-regulated in metastasis HEAT PF02985.22 OQS03841.1 - 0.0056 16.8 4.0 0.97 9.9 0.2 4.9 4 0 0 4 4 4 1 HEAT repeat UME PF08064.13 OQS03841.1 - 0.73 9.8 5.3 3.8 7.5 0.0 4.6 6 0 0 6 6 6 0 UME (NUC010) domain CLAMP PF14769.6 OQS03841.1 - 1.1 9.7 4.2 3 8.3 0.0 4.0 4 0 0 4 4 4 0 Flagellar C1a complex subunit C1a-32 CBM_1 PF00734.18 OQS03842.1 - 2.7e-05 24.0 35.8 0.023 14.6 7.8 4.4 3 1 0 3 3 3 3 Fungal cellulose binding domain Glyco_hydro_72 PF03198.14 OQS03844.1 - 0.00043 19.6 0.0 0.00053 19.3 0.0 1.1 1 0 0 1 1 1 1 Glucanosyltransferase HAUS4 PF14735.6 OQS03845.1 - 8.9e-25 87.8 17.5 1.1e-24 87.4 17.5 1.0 1 0 0 1 1 1 1 HAUS augmin-like complex subunit 4 LRRFIP PF09738.9 OQS03845.1 - 0.16 11.4 12.1 0.036 13.6 1.3 2.2 1 1 1 2 2 2 0 LRRFIP family Syntaxin_2 PF14523.6 OQS03845.1 - 1.3 9.4 18.4 1.6 9.2 14.8 2.7 1 1 1 2 2 2 0 Syntaxin-like protein Glu_cyclase_2 PF05096.12 OQS03846.1 - 1.9e-80 269.9 0.1 2.3e-80 269.7 0.1 1.0 1 0 0 1 1 1 1 Glutamine cyclotransferase SGL PF08450.12 OQS03846.1 - 0.0052 16.4 0.1 0.0098 15.5 0.1 1.5 1 1 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region Arylesterase PF01731.20 OQS03846.1 - 0.016 15.4 0.0 0.42 10.9 0.0 3.1 2 1 1 3 3 3 0 Arylesterase adh_short_C2 PF13561.6 OQS03846.1 - 0.046 13.3 0.0 0.073 12.6 0.0 1.2 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase M157 PF11624.8 OQS03846.1 - 0.083 12.2 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 MHC class I-like protein M157 PFU PF09070.11 OQS03846.1 - 0.13 12.6 0.0 0.26 11.5 0.0 1.5 1 0 0 1 1 1 0 PFU (PLAA family ubiquitin binding) Endonuclease_NS PF01223.23 OQS03847.1 - 1.9e-59 201.3 0.0 2.4e-59 200.9 0.0 1.1 1 0 0 1 1 1 1 DNA/RNA non-specific endonuclease ROK PF00480.20 OQS03848.1 - 4.7e-53 180.6 3.7 5.8e-53 180.3 3.7 1.0 1 0 0 1 1 1 1 ROK family BcrAD_BadFG PF01869.20 OQS03848.1 - 4.9e-06 26.2 0.3 0.038 13.5 0.2 2.4 2 1 0 2 2 2 2 BadF/BadG/BcrA/BcrD ATPase family FGGY_N PF00370.21 OQS03848.1 - 0.00094 18.8 0.0 0.0017 18.0 0.0 1.4 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain Bcl-2_3 PF15286.6 OQS03848.1 - 0.086 13.5 0.0 1.1 9.9 0.0 2.2 2 0 0 2 2 2 0 Apoptosis regulator M11, B cell 2 leukaemia/lymphoma like RRM_1 PF00076.22 OQS03849.1 - 3.5e-33 113.2 0.0 2.7e-15 55.9 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 OQS03849.1 - 1.5e-13 50.7 0.0 1.3e-05 25.2 0.0 3.2 3 1 0 3 3 3 2 RNA recognition motif PHM7_cyt PF14703.6 OQS03849.1 - 0.00026 21.3 0.0 1.3 9.3 0.0 3.1 2 1 1 3 3 3 2 Cytosolic domain of 10TM putative phosphate transporter F-box PF00646.33 OQS03850.1 - 0.0047 16.8 0.1 0.051 13.5 0.0 2.5 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 OQS03850.1 - 0.12 12.3 0.1 0.12 12.3 0.1 2.5 3 0 0 3 3 3 0 F-box-like MIF4G PF02854.19 OQS03851.1 - 8.9e-37 126.8 2.9 1.4e-23 83.7 0.5 2.7 3 0 0 3 3 3 2 MIF4G domain MA3 PF02847.17 OQS03851.1 - 3.4e-22 78.6 2.5 1.9e-11 43.9 0.0 4.3 4 0 0 4 4 4 3 MA3 domain DUF3126 PF11324.8 OQS03851.1 - 0.11 12.4 0.6 0.28 11.0 0.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3126) CHCH PF06747.13 OQS03852.1 - 1.2e-06 28.4 2.8 1.8e-06 27.9 2.8 1.3 1 0 0 1 1 1 1 CHCH domain NDUF_B7 PF05676.13 OQS03852.1 - 0.0031 17.2 1.5 0.0043 16.7 1.5 1.2 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) COX17 PF05051.13 OQS03852.1 - 0.022 15.1 3.6 1.3 9.4 2.0 2.3 1 1 1 2 2 2 0 Cytochrome C oxidase copper chaperone (COX17) Pet191_N PF10203.9 OQS03852.1 - 0.024 14.9 5.2 0.053 13.8 5.0 1.6 1 1 1 2 2 2 0 Cytochrome c oxidase assembly protein PET191 FYTT PF07078.11 OQS03852.1 - 0.051 12.9 0.1 0.062 12.6 0.1 1.1 1 0 0 1 1 1 0 Forty-two-three protein MAPEG PF01124.18 OQS03853.1 - 2.5e-16 59.7 0.0 3.4e-16 59.3 0.0 1.1 1 0 0 1 1 1 1 MAPEG family MAPEG PF01124.18 OQS03854.1 - 8.7e-16 58.0 0.1 1.1e-15 57.7 0.1 1.1 1 0 0 1 1 1 1 MAPEG family CBM9_2 PF16011.5 OQS03855.1 - 5.3e-06 26.3 0.1 1.1e-05 25.3 0.1 1.4 1 0 0 1 1 1 1 Carbohydrate-binding family 9 fn3 PF00041.21 OQS03856.1 - 0.00059 20.1 0.1 0.0008 19.7 0.1 1.2 1 0 0 1 1 1 1 Fibronectin type III domain Interfer-bind PF09294.10 OQS03856.1 - 0.0031 17.8 0.0 0.0034 17.7 0.0 1.1 1 0 0 1 1 1 1 Interferon-alpha/beta receptor, fibronectin type III Oxidored_q6 PF01058.22 OQS03856.1 - 0.028 14.2 0.2 0.036 13.9 0.2 1.3 1 1 0 1 1 1 0 NADH ubiquinone oxidoreductase, 20 Kd subunit Pur_ac_phosph_N PF16656.5 OQS03856.1 - 0.07 13.7 0.1 0.079 13.5 0.1 1.3 1 0 0 1 1 1 0 Purple acid Phosphatase, N-terminal domain MAPEG PF01124.18 OQS03857.1 - 8.9e-05 22.4 9.2 9.2e-05 22.4 7.9 1.6 1 1 1 2 2 2 1 MAPEG family Aa_trans PF01490.18 OQS03858.1 - 0.0013 17.5 8.5 0.002 16.9 8.6 1.3 1 1 0 1 1 1 1 Transmembrane amino acid transporter protein Flp1_like PF16982.5 OQS03858.1 - 0.084 12.3 0.2 0.084 12.3 0.2 1.7 2 0 0 2 2 2 0 Putative Flagellin, Flp1-like, domain ATP-synt_I PF03899.15 OQS03858.1 - 0.12 12.7 7.2 0.26 11.6 0.0 2.8 3 0 0 3 3 3 0 ATP synthase I chain DUF5368 PF17336.2 OQS03858.1 - 0.19 11.9 2.0 0.35 11.1 2.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5368) DUF2157 PF09925.9 OQS03858.1 - 0.3 10.9 6.3 0.27 11.0 1.2 2.6 2 1 1 3 3 3 0 Predicted membrane protein (DUF2157) zf-RVT PF13966.6 OQS03859.1 - 0.0023 18.6 0.6 0.0023 18.6 0.6 2.2 2 0 0 2 2 2 1 zinc-binding in reverse transcriptase Cystatin PF00031.21 OQS03862.1 - 0.042 14.1 0.4 0.06 13.6 0.4 1.4 1 0 0 1 1 1 0 Cystatin domain EGF_2 PF07974.13 OQS03863.1 - 2.7e-26 91.6 120.1 1.5e-05 25.3 5.1 10.4 8 3 0 8 8 8 8 EGF-like domain Anoctamin PF04547.12 OQS03863.1 - 6.1e-18 64.9 5.6 9.4e-18 64.3 5.6 1.3 1 0 0 1 1 1 1 Calcium-activated chloride channel Ank_2 PF12796.7 OQS03863.1 - 6.6e-18 65.1 0.0 0.00021 21.8 0.0 4.9 3 1 1 4 4 4 4 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OQS03863.1 - 8.8e-12 44.1 1.2 1.7 9.4 0.0 7.0 6 0 0 6 6 6 2 Ankyrin repeat Ank_4 PF13637.6 OQS03863.1 - 3.3e-09 37.1 0.1 0.038 14.6 0.0 5.3 4 1 0 4 4 4 2 Ankyrin repeats (many copies) EGF PF00008.27 OQS03863.1 - 1.8e-06 28.1 101.4 0.0037 17.5 2.5 10.9 10 0 0 10 10 10 5 EGF-like domain Ank_5 PF13857.6 OQS03863.1 - 6.9e-06 26.2 0.0 1.5 9.3 0.0 5.0 4 0 0 4 4 4 2 Ankyrin repeats (many copies) Ank PF00023.30 OQS03863.1 - 1.8e-05 24.9 4.9 2.2 8.9 0.0 5.9 6 0 0 6 6 6 2 Ankyrin repeat Rpn9_C PF18261.1 OQS03863.1 - 0.18 11.4 0.1 0.35 10.5 0.1 1.5 1 0 0 1 1 1 0 Rpn9 C-terminal helix DUF3072 PF11272.8 OQS03863.1 - 0.26 11.2 0.5 13 5.7 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3072) IQ PF00612.27 OQS03863.1 - 1.2 9.1 6.1 4.1 7.5 1.0 2.8 2 0 0 2 2 2 0 IQ calmodulin-binding motif ETF_QO PF05187.13 OQS03864.1 - 2e-37 127.5 0.1 3.3e-37 126.8 0.1 1.3 1 0 0 1 1 1 1 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S FAD_binding_2 PF00890.24 OQS03864.1 - 1.5e-05 24.3 0.7 0.00077 18.7 1.1 2.2 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.24 OQS03864.1 - 2.3e-05 24.2 0.2 0.035 13.7 0.2 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase Thi4 PF01946.17 OQS03864.1 - 0.00017 20.9 0.0 0.0019 17.5 0.1 2.0 2 0 0 2 2 2 1 Thi4 family NAD_binding_8 PF13450.6 OQS03864.1 - 0.00043 20.4 0.0 0.0021 18.2 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 OQS03864.1 - 0.0013 17.8 0.1 0.0024 17.0 0.1 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.14 OQS03864.1 - 0.0029 16.9 0.0 0.0048 16.2 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 OQS03864.1 - 0.013 14.7 0.2 0.021 14.1 0.2 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 OQS03864.1 - 0.017 14.4 0.1 0.03 13.6 0.1 1.4 1 0 0 1 1 1 0 FAD binding domain NAD_binding_9 PF13454.6 OQS03864.1 - 0.022 14.7 0.0 0.043 13.8 0.0 1.4 1 0 0 1 1 1 0 FAD-NAD(P)-binding Fer4_7 PF12838.7 OQS03864.1 - 0.027 15.1 2.6 0.075 13.6 2.6 1.7 1 0 0 1 1 1 0 4Fe-4S dicluster domain HI0933_like PF03486.14 OQS03864.1 - 0.038 12.7 0.2 0.056 12.1 0.2 1.2 1 0 0 1 1 1 0 HI0933-like protein K_oxygenase PF13434.6 OQS03864.1 - 0.045 12.9 0.0 0.065 12.4 0.0 1.2 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox PF00070.27 OQS03864.1 - 0.052 14.1 1.3 6.1 7.5 0.0 2.8 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase PhoD_N PF16655.5 OQS03865.1 - 0.025 15.1 0.0 0.078 13.5 0.0 1.9 1 0 0 1 1 1 0 PhoD-like phosphatase, N-terminal domain Helo_like_N PF17111.5 OQS03865.1 - 0.036 13.4 2.6 0.079 12.3 2.6 1.6 1 0 0 1 1 1 0 Fungal N-terminal domain of STAND proteins PARP PF00644.20 OQS03866.1 - 6.2e-45 153.2 0.0 1.1e-44 152.4 0.0 1.4 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain EGF_2 PF07974.13 OQS03867.1 - 5.6e-08 33.0 53.2 0.0008 19.7 1.7 5.1 3 1 1 4 4 4 3 EGF-like domain EGF PF00008.27 OQS03867.1 - 0.003 17.8 1.5 0.003 17.8 1.5 4.4 3 0 0 3 3 3 2 EGF-like domain Laminin_EGF PF00053.24 OQS03867.1 - 0.0083 16.2 14.8 0.0083 16.2 14.8 4.4 2 2 1 4 4 4 2 Laminin EGF domain hEGF PF12661.7 OQS03867.1 - 0.035 14.7 4.6 0.035 14.7 4.6 5.1 4 0 0 4 4 4 0 Human growth factor-like EGF Ank_2 PF12796.7 OQS03868.1 - 1.1e-08 35.5 2.6 2.5e-05 24.8 0.1 2.7 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQS03868.1 - 5e-07 30.1 2.0 0.0014 19.2 0.1 3.5 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQS03868.1 - 8.4e-06 25.8 2.9 0.025 15.1 0.1 3.7 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 OQS03868.1 - 0.00013 22.2 2.4 0.0051 17.1 1.0 2.5 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.30 OQS03868.1 - 0.00021 21.6 2.2 0.001 19.4 0.2 2.8 2 1 0 2 2 2 1 Ankyrin repeat DUF2423 PF10338.9 OQS03869.1 - 1.5e-07 31.5 1.1 1.5e-07 31.5 1.1 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF2423) MgsA_C PF12002.8 OQS03870.1 - 9.9e-52 175.2 0.5 2e-49 167.7 0.5 2.4 1 1 0 1 1 1 1 MgsA AAA+ ATPase C terminal AAA_assoc_2 PF16193.5 OQS03870.1 - 1.9e-27 95.4 0.1 4.6e-27 94.2 0.1 1.6 1 0 0 1 1 1 1 AAA C-terminal domain AAA PF00004.29 OQS03870.1 - 2.9e-15 56.9 0.0 5.4e-15 56.0 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 OQS03870.1 - 1.7e-12 47.4 0.0 3.3e-12 46.4 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 OQS03870.1 - 1.8e-08 34.5 0.0 5.7e-08 32.8 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 OQS03870.1 - 9.3e-06 26.1 0.0 0.00085 19.7 0.0 2.5 1 1 1 2 2 2 1 AAA ATPase domain Mg_chelatase PF01078.21 OQS03870.1 - 1.8e-05 24.2 0.1 0.01 15.2 0.0 2.2 1 1 1 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_14 PF13173.6 OQS03870.1 - 5.1e-05 23.3 0.0 8.9e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 OQS03870.1 - 0.00012 21.8 0.0 0.00022 21.0 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein Sigma54_activat PF00158.26 OQS03870.1 - 0.00019 21.2 0.0 0.012 15.3 0.0 2.2 1 1 0 1 1 1 1 Sigma-54 interaction domain TIP49 PF06068.13 OQS03870.1 - 0.00037 19.8 0.1 0.0012 18.1 0.0 1.7 1 1 1 2 2 2 1 TIP49 P-loop domain AAA_30 PF13604.6 OQS03870.1 - 0.0005 19.8 0.0 0.0013 18.5 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_3 PF07726.11 OQS03870.1 - 0.0007 19.5 0.0 0.0012 18.7 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 OQS03870.1 - 0.0014 18.9 0.1 0.015 15.6 0.1 2.3 1 1 0 1 1 1 1 AAA domain AAA_2 PF07724.14 OQS03870.1 - 0.0022 18.1 0.0 0.0037 17.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) RNA_helicase PF00910.22 OQS03870.1 - 0.0038 17.6 0.0 0.007 16.8 0.0 1.4 1 0 0 1 1 1 1 RNA helicase AAA_19 PF13245.6 OQS03870.1 - 0.007 16.7 0.1 0.52 10.6 0.1 2.2 1 1 1 2 2 2 1 AAA domain RNF220 PF15926.5 OQS03870.1 - 0.0074 15.9 0.0 0.012 15.3 0.0 1.3 1 0 0 1 1 1 1 E3 ubiquitin-protein ligase RNF220 ResIII PF04851.15 OQS03870.1 - 0.013 15.5 0.0 3.2 7.7 0.0 2.3 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit DUF815 PF05673.13 OQS03870.1 - 0.027 13.6 0.0 0.045 12.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Sigma54_activ_2 PF14532.6 OQS03870.1 - 0.028 14.6 0.0 0.058 13.5 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_24 PF13479.6 OQS03870.1 - 0.033 13.9 0.0 0.054 13.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 OQS03870.1 - 0.038 13.9 0.0 0.44 10.4 0.0 2.1 1 1 1 2 2 2 0 ATPase domain predominantly from Archaea MCM PF00493.23 OQS03870.1 - 0.05 12.7 0.0 0.081 12.0 0.0 1.3 1 0 0 1 1 1 0 MCM P-loop domain ABC_tran PF00005.27 OQS03870.1 - 0.061 13.8 0.0 0.13 12.8 0.0 1.5 1 0 0 1 1 1 0 ABC transporter Zeta_toxin PF06414.12 OQS03870.1 - 0.07 12.4 0.0 0.24 10.7 0.0 1.8 2 0 0 2 2 2 0 Zeta toxin AAA_25 PF13481.6 OQS03870.1 - 0.11 12.1 0.0 0.2 11.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 OQS03870.1 - 0.11 12.3 0.0 0.23 11.3 0.0 1.5 1 0 0 1 1 1 0 NACHT domain TniB PF05621.11 OQS03870.1 - 0.18 11.2 0.0 1.2 8.5 0.0 2.1 1 1 1 2 2 2 0 Bacterial TniB protein Aa_trans PF01490.18 OQS03871.1 - 2.2e-53 181.4 21.9 2.7e-53 181.2 21.9 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 OQS03871.1 - 1.7e-08 33.9 14.9 1.7e-08 33.9 14.9 2.1 2 0 0 2 2 2 1 Tryptophan/tyrosine permease family DUF3687 PF12459.8 OQS03871.1 - 0.034 13.7 0.2 0.034 13.7 0.2 2.6 2 0 0 2 2 2 0 D-Ala-teichoic acid biosynthesis protein MscS_TM PF12794.7 OQS03871.1 - 3.6 6.3 17.6 0.61 8.9 5.2 2.8 3 0 0 3 3 3 0 Mechanosensitive ion channel inner membrane domain 1 BBS2_Mid PF14783.6 OQS03872.1 - 4.7e-09 36.2 0.0 2.8e-08 33.8 0.0 2.3 2 0 0 2 2 2 1 Ciliary BBSome complex subunit 2, middle region BBS2_C PF14782.6 OQS03872.1 - 0.0022 16.8 0.1 0.038 12.7 0.0 2.2 1 1 1 2 2 2 1 Ciliary BBSome complex subunit 2, C-terminal CNV-Replicase_N PF16688.5 OQS03872.1 - 0.028 14.7 0.3 0.083 13.2 0.0 1.9 2 0 0 2 2 2 0 Replicase polyprotein N-term from Coronavirus nsp1 VCBS PF13517.6 OQS03872.1 - 0.079 13.6 0.2 0.35 11.5 0.0 2.2 2 0 0 2 2 2 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella Ank_2 PF12796.7 OQS03874.1 - 1.1e-30 106.0 7.4 3.9e-08 33.8 0.5 4.9 1 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQS03874.1 - 3.2e-26 91.3 13.7 1.9e-05 25.1 0.1 6.8 4 1 2 6 6 6 6 Ankyrin repeats (many copies) Ank_5 PF13857.6 OQS03874.1 - 2.2e-22 78.8 14.9 0.044 14.1 0.1 10.0 2 2 8 10 10 10 8 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQS03874.1 - 2e-16 58.4 8.9 0.38 11.4 0.0 10.3 9 2 2 11 11 11 4 Ankyrin repeat DUF5049 PF16468.5 OQS03874.1 - 5.4e-10 39.0 8.4 0.53 10.2 0.1 8.7 7 3 3 10 10 10 3 Domain of unknown function (DUF5049) Ank PF00023.30 OQS03874.1 - 1.7e-06 28.2 8.3 19 5.9 0.1 8.2 6 3 3 9 9 9 1 Ankyrin repeat Tom37 PF10568.9 OQS03874.1 - 0.057 13.7 0.0 35 4.7 0.0 4.5 3 2 0 3 3 3 0 Outer mitochondrial membrane transport complex protein CNOT1_CAF1_bind PF16415.5 OQS03875.1 - 8.9e-84 280.4 0.7 7.5e-83 277.3 0.2 2.5 2 0 0 2 2 2 1 CCR4-NOT transcription complex subunit 1 CAF1-binding domain CNOT1_TTP_bind PF16417.5 OQS03875.1 - 1.8e-54 183.8 0.5 3.7e-54 182.8 0.5 1.4 1 0 0 1 1 1 1 CCR4-NOT transcription complex subunit 1 TTP binding domain DUF3819 PF12842.7 OQS03875.1 - 2e-54 183.5 0.9 2e-54 183.5 0.9 2.7 3 0 0 3 3 3 1 Domain of unknown function (DUF3819) CNOT1_HEAT PF16418.5 OQS03875.1 - 3.8e-18 66.0 0.1 9.9e-18 64.6 0.1 1.8 1 0 0 1 1 1 1 CCR4-NOT transcription complex subunit 1 HEAT repeat Peptidase_C1 PF00112.23 OQS03876.1 - 4.4e-31 108.7 7.7 3.7e-30 105.7 7.7 2.1 1 1 0 1 1 1 1 Papain family cysteine protease DUF5045 PF16464.5 OQS03876.1 - 0.088 13.1 0.0 0.21 11.9 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF5045) NES_C_h PF18208.1 OQS03876.1 - 0.098 12.9 0.1 0.15 12.4 0.1 1.2 1 0 0 1 1 1 0 Nicking enzyme C-terminal middle helical domain Tex_N PF09371.10 OQS03876.1 - 0.2 11.3 0.3 0.31 10.7 0.3 1.2 1 0 0 1 1 1 0 Tex-like protein N-terminal domain Aldolase_II PF00596.21 OQS03877.1 - 1.1e-41 142.9 0.3 2.3e-41 141.8 0.3 1.6 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain PLDc_2 PF13091.6 OQS03877.1 - 1.6e-23 83.1 0.0 1.4e-16 60.6 0.1 2.6 2 0 0 2 2 2 2 PLD-like domain PLDc_3 PF13918.6 OQS03877.1 - 2e-22 79.7 0.0 7.4e-21 74.6 0.0 2.9 3 0 0 3 3 3 1 PLD-like domain PLDc PF00614.22 OQS03877.1 - 2.5e-12 46.4 2.6 1.7e-07 31.1 0.4 2.8 2 0 0 2 2 2 2 Phospholipase D Active site motif EF-hand_8 PF13833.6 OQS03877.1 - 0.0002 21.1 0.1 0.00094 19.0 0.0 2.2 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_7 PF13499.6 OQS03877.1 - 0.0014 19.0 4.4 0.9 10.0 0.2 3.1 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.6 OQS03877.1 - 0.084 12.8 0.1 0.33 11.0 0.1 2.0 1 0 0 1 1 1 0 EF-hand domain PhoLip_ATPase_C PF16212.5 OQS03878.1 - 1.8e-60 204.8 21.8 1.8e-60 204.8 21.8 2.4 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 OQS03878.1 - 2.3e-21 75.3 1.0 2.3e-21 75.3 1.0 2.3 2 0 0 2 2 2 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 OQS03878.1 - 2.2e-13 51.0 0.0 5.8e-06 26.7 0.0 2.7 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 OQS03878.1 - 1.5e-09 37.8 0.0 2e-08 34.2 0.0 2.3 2 0 0 2 2 2 1 Cation transport ATPase (P-type) E1-E2_ATPase PF00122.20 OQS03878.1 - 1.1e-08 34.9 2.8 1.8e-08 34.1 0.0 2.8 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase_3 PF08282.12 OQS03878.1 - 7.1e-07 29.2 0.0 1.6e-06 28.1 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 OQS03878.1 - 0.018 15.5 0.0 0.27 11.6 0.0 2.5 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase DUF1797 PF08796.10 OQS03879.1 - 0.013 15.5 0.3 0.78 9.9 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1797) LPD3 PF18798.1 OQS03879.1 - 0.025 14.8 1.0 0.16 12.2 0.0 2.6 3 0 0 3 3 3 0 Large polyvalent protein-associated domain 3 DUF4296 PF14129.6 OQS03879.1 - 0.03 14.9 14.3 0.37 11.4 0.5 5.1 4 1 1 5 5 5 0 Domain of unknown function (DUF4296) RRF PF01765.19 OQS03879.1 - 0.055 13.4 6.6 0.028 14.4 1.4 2.6 2 1 0 2 2 2 0 Ribosome recycling factor Cas_Cas2CT1978 PF09707.10 OQS03879.1 - 0.11 12.6 0.0 13 5.9 0.0 2.9 2 0 0 2 2 2 0 CRISPR-associated protein (Cas_Cas2CT1978) PilN_bio_d PF18222.1 OQS03879.1 - 0.13 12.7 0.8 0.44 11.0 0.8 1.9 1 0 0 1 1 1 0 PilN biogenesis protein dimerization domain DUF3892 PF13031.6 OQS03879.1 - 0.21 12.2 1.2 14 6.4 0.3 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3892) Mobilization_B PF17511.2 OQS03879.1 - 1.6 9.1 9.1 0.096 13.1 1.2 2.8 3 0 0 3 3 3 0 Mobilization protein B PEP-utilisers_N PF05524.13 OQS03879.1 - 5.3 7.2 20.2 0.1 12.7 3.3 3.9 2 2 1 3 3 3 0 PEP-utilising enzyme, N-terminal Mito_carr PF00153.27 OQS03880.1 - 4.6e-65 215.6 1.5 1.2e-20 73.3 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein zf-RanBP PF00641.18 OQS03881.1 - 3.9e-06 26.1 1.2 6.6e-06 25.3 1.2 1.4 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others Vps36-NZF-N PF16988.5 OQS03881.1 - 0.002 17.5 6.2 0.012 14.9 6.2 2.0 1 1 0 1 1 1 1 Vacuolar protein sorting 36 NZF-N zinc-finger domain zf-MIZ PF02891.20 OQS03881.1 - 0.057 13.2 1.4 0.092 12.5 1.4 1.4 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger Rubredoxin_2 PF18073.1 OQS03881.1 - 0.15 11.8 2.4 2.8 7.7 0.1 2.3 2 0 0 2 2 2 0 Rubredoxin metal binding domain zf-Sec23_Sec24 PF04810.15 OQS03881.1 - 1.2 9.3 5.4 0.69 10.0 1.5 2.1 1 1 1 2 2 2 0 Sec23/Sec24 zinc finger 5_nucleotid_C PF02872.18 OQS03882.1 - 5.9e-18 65.6 0.0 8.1e-18 65.1 0.0 1.1 1 0 0 1 1 1 1 5'-nucleotidase, C-terminal domain TUSC2 PF15000.6 OQS03883.1 - 2.3 8.5 8.0 2.9 8.2 4.0 2.7 2 1 0 2 2 2 0 Tumour suppressor candidate 2 DUF1846 PF08903.11 OQS03883.1 - 5.7 5.4 8.8 9.3 4.7 8.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1846) DRMBL PF07522.14 OQS03885.1 - 1.1e-26 93.1 0.5 3.2e-25 88.5 0.5 2.9 1 1 0 1 1 1 1 DNA repair metallo-beta-lactamase Lactamase_B_2 PF12706.7 OQS03885.1 - 0.00052 19.6 0.0 0.0013 18.3 0.0 1.6 1 0 0 1 1 1 1 Beta-lactamase superfamily domain RMMBL PF07521.12 OQS03885.1 - 0.12 12.3 0.0 0.25 11.3 0.0 1.4 1 0 0 1 1 1 0 Zn-dependent metallo-hydrolase RNA specificity domain zf-C2H2_3 PF13878.6 OQS03885.1 - 0.18 11.7 1.3 0.34 10.8 0.0 2.2 2 0 0 2 2 2 0 zinc-finger of acetyl-transferase ESCO Aldedh PF00171.22 OQS03886.1 - 1.3e-180 600.9 0.0 1.3e-180 600.9 0.0 1.9 3 0 0 3 3 3 1 Aldehyde dehydrogenase family DtxR PF18357.1 OQS03886.1 - 0.064 12.9 0.8 0.15 11.8 0.1 2.1 2 0 0 2 2 2 0 Diphteria toxin repressor SH3 domain DUF1084 PF06454.11 OQS03887.1 - 5.1e-06 26.1 11.8 8.6e-06 25.3 11.8 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1084) HIG_1_N PF04588.13 OQS03887.1 - 0.12 12.6 2.5 2.1 8.6 0.2 3.4 3 0 0 3 3 3 0 Hypoxia induced protein conserved region DUF2304 PF10066.9 OQS03887.1 - 4.6 7.5 9.1 0.84 9.9 4.0 2.4 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2304) DUF1765 PF08578.10 OQS03888.1 - 3.4e-11 43.7 3.6 1.1e-10 42.0 3.6 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF1765) PWI PF01480.17 OQS03888.1 - 0.57 10.5 2.8 1.8 8.9 0.1 3.0 3 0 0 3 3 3 0 PWI domain GBP PF02263.19 OQS03889.1 - 1.7e-08 34.1 0.3 2.3e-07 30.4 0.0 2.5 2 0 0 2 2 2 1 Guanylate-binding protein, N-terminal domain GBP_C PF02841.14 OQS03889.1 - 1.3e-05 24.8 0.6 1.3e-05 24.8 0.6 3.6 2 1 1 3 3 3 2 Guanylate-binding protein, C-terminal domain LPP PF04728.13 OQS03889.1 - 0.54 10.7 6.4 0.53 10.7 1.8 3.2 2 0 0 2 2 2 0 Lipoprotein leucine-zipper Pkinase_Tyr PF07714.17 OQS03890.1 - 2.8e-55 187.4 0.0 3.9e-55 186.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OQS03890.1 - 1.5e-39 136.0 0.0 2.5e-39 135.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 OQS03890.1 - 0.033 13.6 0.0 0.056 12.8 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 OQS03890.1 - 0.048 12.4 0.1 0.084 11.6 0.1 1.3 1 0 0 1 1 1 0 Fungal protein kinase Mito_carr PF00153.27 OQS03891.1 - 2.1e-60 200.6 0.5 1.9e-19 69.4 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein RNB PF00773.19 OQS03892.1 - 1.9e-92 310.1 0.0 1.9e-92 310.1 0.0 2.1 2 1 0 2 2 2 1 RNB domain OB_Dis3 PF17849.1 OQS03892.1 - 5.3e-16 58.4 0.0 1.2e-15 57.3 0.0 1.7 1 0 0 1 1 1 1 Dis3-like cold-shock domain 2 (CSD2) Rrp44_CSD1 PF17216.3 OQS03892.1 - 5.6e-08 32.6 5.5 9.9e-08 31.8 0.0 2.7 3 0 0 3 3 3 1 Rrp44-like cold shock domain Dis3l2_C_term PF17877.1 OQS03892.1 - 6.3e-08 32.9 2.7 8.9e-08 32.4 0.0 2.8 2 1 1 3 3 3 1 DIS3-like exonuclease 2 C terminal CSD2 PF17876.1 OQS03892.1 - 0.058 13.6 0.1 8.4 6.6 0.1 2.8 2 0 0 2 2 2 0 Cold shock domain OB_RNB PF08206.11 OQS03892.1 - 0.076 12.7 0.2 0.18 11.5 0.2 1.6 1 0 0 1 1 1 0 Ribonuclease B OB domain PET117 PF15786.5 OQS03892.1 - 0.15 12.4 0.1 0.15 12.4 0.1 2.5 2 0 0 2 2 2 0 PET assembly of cytochrome c oxidase, mitochondrial ABC2_membrane PF01061.24 OQS03893.1 - 7.3e-65 218.3 70.3 1e-35 123.1 27.4 3.1 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.27 OQS03893.1 - 3e-29 102.3 0.0 4e-14 53.3 0.0 2.4 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 OQS03893.1 - 3.1e-07 30.5 0.8 0.045 13.6 0.0 3.3 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 OQS03893.1 - 6.1e-07 30.0 0.1 0.042 14.2 0.0 2.4 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.6 OQS03893.1 - 1.3e-06 28.1 2.3 0.023 14.4 0.8 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 OQS03893.1 - 9.4e-06 25.6 3.3 0.015 15.2 0.5 2.7 2 1 1 3 3 3 2 RsgA GTPase Zeta_toxin PF06414.12 OQS03893.1 - 2e-05 23.9 0.5 0.0031 16.8 0.0 2.4 2 0 0 2 2 2 1 Zeta toxin AAA_22 PF13401.6 OQS03893.1 - 5e-05 23.6 0.2 0.14 12.4 0.0 2.8 2 0 0 2 2 2 2 AAA domain PDR_CDR PF06422.12 OQS03893.1 - 7.7e-05 22.5 13.5 0.00068 19.5 0.5 4.4 4 0 0 4 4 4 2 CDR ABC transporter SMC_N PF02463.19 OQS03893.1 - 0.002 17.6 0.7 7.7 5.9 0.0 4.2 5 0 0 5 5 5 0 RecF/RecN/SMC N terminal domain AAA_18 PF13238.6 OQS03893.1 - 0.0023 18.5 0.0 1.3 9.6 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 OQS03893.1 - 0.003 18.0 0.0 7.3 7.0 0.0 3.2 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_23 PF13476.6 OQS03893.1 - 0.0067 17.0 1.4 0.76 10.2 0.6 2.4 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 OQS03893.1 - 0.0077 16.3 1.0 1.6 8.9 0.0 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_30 PF13604.6 OQS03893.1 - 0.009 15.7 0.5 3.4 7.3 0.4 2.4 2 0 0 2 2 2 1 AAA domain DUF2075 PF09848.9 OQS03893.1 - 0.037 13.3 0.0 0.29 10.3 0.0 2.0 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) RNA_helicase PF00910.22 OQS03893.1 - 0.04 14.3 0.3 12 6.3 0.0 2.8 2 0 0 2 2 2 0 RNA helicase AAA_5 PF07728.14 OQS03893.1 - 0.058 13.4 0.2 1.9 8.4 0.1 2.6 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Ploopntkinase3 PF18751.1 OQS03893.1 - 0.067 13.1 0.3 0.89 9.4 0.0 2.2 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 AAA_24 PF13479.6 OQS03893.1 - 0.07 12.8 1.5 8.5 6.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 OQS03893.1 - 0.099 12.8 0.1 14 5.8 0.1 2.4 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 OQS03893.1 - 0.1 12.1 2.4 1 8.9 0.4 2.6 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 OQS03893.1 - 0.13 12.2 3.7 7.1 6.5 0.2 2.5 2 0 0 2 2 2 0 NACHT domain DUF87 PF01935.17 OQS03893.1 - 0.14 12.2 3.7 2.9 7.9 0.0 2.4 2 0 0 2 2 2 0 Helicase HerA, central domain PduV-EutP PF10662.9 OQS03893.1 - 0.14 11.9 0.9 5.4 6.8 0.4 2.6 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation DUF815 PF05673.13 OQS03893.1 - 0.16 11.1 0.3 0.35 10.0 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF815) cobW PF02492.19 OQS03893.1 - 0.33 10.5 3.0 3.2 7.3 0.7 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain PDR_assoc PF08370.11 OQS03893.1 - 7.8 6.3 23.7 0.26 11.1 0.9 4.7 4 0 0 4 4 3 0 Plant PDR ABC transporter associated Carb_anhydrase PF00194.21 OQS03894.1 - 6.5e-36 124.2 0.0 1.2e-35 123.2 0.0 1.4 1 1 0 1 1 1 1 Eukaryotic-type carbonic anhydrase ADH_zinc_N PF00107.26 OQS03896.1 - 1.4e-14 54.2 0.4 3.3e-14 53.0 0.1 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 OQS03896.1 - 2e-10 41.8 0.1 5.7e-10 40.4 0.0 1.8 3 0 0 3 3 3 1 Zinc-binding dehydrogenase ADH_N PF08240.12 OQS03896.1 - 2.2e-09 37.1 0.0 5.1e-09 36.0 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain EcKinase PF02958.20 OQS03896.1 - 0.057 12.7 0.0 0.082 12.2 0.0 1.2 1 0 0 1 1 1 0 Ecdysteroid kinase Forkhead PF00250.18 OQS03897.1 - 0.002 18.4 3.7 0.49 10.7 0.4 2.9 3 0 0 3 3 3 2 Forkhead domain Ank_2 PF12796.7 OQS03897.1 - 0.0022 18.5 0.0 0.21 12.2 0.0 3.0 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) DUF5049 PF16468.5 OQS03897.1 - 0.011 15.6 4.3 23 5.0 0.0 4.6 4 1 1 5 5 5 0 Domain of unknown function (DUF5049) Ank_3 PF13606.6 OQS03897.1 - 0.028 14.9 0.1 27 5.8 0.0 4.4 5 0 0 5 5 5 0 Ankyrin repeat DUF1843 PF08898.10 OQS03897.1 - 0.11 13.1 0.0 0.33 11.5 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1843) ABC_tran PF00005.27 OQS03899.1 - 1.3e-16 61.3 0.0 1e-13 52.0 0.0 2.5 1 1 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 OQS03899.1 - 9.3e-05 22.4 0.3 0.00032 20.6 0.0 1.9 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 OQS03899.1 - 0.062 13.7 0.0 0.12 12.7 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain Abhydrolase_1 PF00561.20 OQS03902.1 - 1.3e-15 57.8 0.0 2.8e-15 56.6 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 OQS03902.1 - 4.2e-11 42.6 0.3 2.8e-10 39.9 0.3 2.0 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 OQS03902.1 - 2.2e-07 31.7 0.1 3.2e-07 31.2 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Palm_thioest PF02089.15 OQS03902.1 - 0.00029 20.8 0.0 0.00053 19.9 0.0 1.4 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Peptidase_S15 PF02129.18 OQS03902.1 - 0.00043 20.0 0.0 0.00095 18.8 0.0 1.5 2 0 0 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) ORC3_N PF07034.11 OQS03902.1 - 0.018 14.1 0.0 0.026 13.7 0.0 1.2 1 0 0 1 1 1 0 Origin recognition complex (ORC) subunit 3 N-terminus DUF915 PF06028.11 OQS03902.1 - 0.036 13.4 0.0 0.32 10.3 0.0 2.0 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) MazG_C PF18722.1 OQS03902.1 - 0.099 12.1 0.0 0.27 10.7 0.0 1.7 2 0 0 2 2 2 0 MazG C-terminal domain Daxx PF03344.15 OQS03902.1 - 0.15 12.2 0.1 0.59 10.2 0.0 2.1 2 0 0 2 2 2 0 Daxx N-terminal Rassf1C-interacting domain Myb_DNA-binding PF00249.31 OQS03903.1 - 3.2e-11 43.2 0.1 2.3e-10 40.5 0.1 2.2 2 0 0 2 2 2 1 Myb-like DNA-binding domain LRR_6 PF13516.6 OQS03903.1 - 2.8e-09 36.3 7.9 0.048 13.7 0.0 6.6 7 0 0 7 7 7 4 Leucine Rich repeat LRR_4 PF12799.7 OQS03903.1 - 3.5e-06 27.3 4.9 0.11 13.0 0.2 5.2 2 1 1 4 4 4 3 Leucine Rich repeats (2 copies) Macoilin PF09726.9 OQS03903.1 - 6.1e-06 25.1 16.9 0.00017 20.3 4.0 3.7 3 1 0 3 3 3 2 Macoilin family Myb_DNA-bind_7 PF15963.5 OQS03903.1 - 2.8e-05 23.9 0.4 2.8e-05 23.9 0.4 3.2 4 0 0 4 4 4 1 Myb DNA-binding like LRR_8 PF13855.6 OQS03903.1 - 0.00018 21.2 1.5 0.059 13.1 0.3 3.7 4 0 0 4 4 4 1 Leucine rich repeat Myb_DNA-bind_6 PF13921.6 OQS03903.1 - 0.00036 20.7 1.2 0.00095 19.4 0.4 2.2 2 0 0 2 2 2 1 Myb-like DNA-binding domain LRR_1 PF00560.33 OQS03903.1 - 4.1 8.3 12.3 5.8 7.9 0.3 5.5 5 1 0 5 5 5 0 Leucine Rich Repeat PALP PF00291.25 OQS03904.1 - 2.1e-07 30.7 0.0 2.9e-07 30.2 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme DUF4125 PF13526.6 OQS03905.1 - 0.14 11.7 0.9 0.29 10.7 0.2 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF4125) BT1 PF03092.16 OQS03906.1 - 5.6e-29 100.8 26.9 9.9e-17 60.3 0.7 4.3 4 1 0 5 5 5 3 BT1 family PUCC PF03209.15 OQS03906.1 - 5.2e-08 32.3 22.2 8.8e-05 21.7 2.6 2.8 2 1 1 3 3 3 2 PUCC protein DUF2545 PF10810.8 OQS03906.1 - 0.055 13.6 6.9 3.2 8.0 0.4 3.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2545) DUF2953 PF11167.8 OQS03906.1 - 0.91 9.6 8.5 1.8 8.7 0.1 4.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2953) Pirin PF02678.16 OQS03907.1 - 2.8e-27 94.8 0.0 9.1e-27 93.2 0.0 1.9 3 0 0 3 3 3 1 Pirin Pirin_C PF05726.13 OQS03907.1 - 4.6e-27 94.4 0.0 1.9e-26 92.4 0.0 1.8 2 0 0 2 2 2 1 Pirin C-terminal cupin domain Pirin_C_2 PF17954.1 OQS03907.1 - 0.17 12.1 0.0 0.31 11.3 0.0 1.4 1 0 0 1 1 1 0 Quercetinase C-terminal cupin domain Amidase PF01425.21 OQS03908.1 - 1.3e-46 159.5 0.1 1.7e-46 159.2 0.1 1.1 1 0 0 1 1 1 1 Amidase DUF1565 PF07602.11 OQS03910.1 - 0.11 11.8 0.0 0.15 11.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1565) Ank_2 PF12796.7 OQS03912.1 - 2.2e-50 169.2 17.3 1.5e-16 60.8 0.9 6.9 4 2 3 7 7 7 6 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OQS03912.1 - 1.2e-39 133.8 9.2 1.1e-12 47.9 0.0 9.8 5 3 5 10 10 10 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQS03912.1 - 6.3e-39 127.5 7.2 2.4e-06 27.4 0.0 11.5 11 0 0 11 11 11 8 Ankyrin repeat Ank_4 PF13637.6 OQS03912.1 - 3.6e-38 129.5 5.8 2.6e-10 40.6 0.0 9.2 4 2 4 9 9 9 8 Ankyrin repeats (many copies) Ank PF00023.30 OQS03912.1 - 1.3e-33 113.9 7.3 6e-06 26.5 0.0 9.3 8 0 0 8 8 8 7 Ankyrin repeat Ion_trans PF00520.31 OQS03912.1 - 0.00012 21.5 30.8 0.00012 21.5 30.8 2.0 2 0 0 2 2 2 1 Ion transport protein PEARLI-4 PF05278.12 OQS03912.1 - 0.2 11.2 16.8 0.47 10.0 16.8 1.5 1 0 0 1 1 1 0 Arabidopsis phospholipase-like protein (PEARLI 4) RP-C_C PF11800.8 OQS03912.1 - 1.4 9.0 10.2 3.1 7.8 10.2 1.6 1 0 0 1 1 1 0 Replication protein C C-terminal region Asp PF00026.23 OQS03913.1 - 8.4e-18 64.8 4.6 2.1e-16 60.3 4.6 2.0 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 OQS03913.1 - 4.1e-15 56.5 2.5 7.6e-15 55.6 2.5 1.5 1 0 0 1 1 1 1 Xylanase inhibitor N-terminal TAXi_C PF14541.6 OQS03913.1 - 5.1e-08 32.9 0.1 5.7e-07 29.5 0.1 2.6 2 1 0 2 2 2 1 Xylanase inhibitor C-terminal zf-RRPl_C4 PF17026.5 OQS03913.1 - 0.015 15.4 0.9 0.032 14.3 0.9 1.5 1 0 0 1 1 1 0 Putative ribonucleoprotein zinc-finger pf C4 type GlcNAc PF11397.8 OQS03914.1 - 2.5e-48 165.3 0.1 9e-40 137.2 0.0 2.2 1 1 1 2 2 2 2 Glycosyltransferase (GlcNAc) PilN_bio_d PF18222.1 OQS03914.1 - 0.2 12.0 0.0 0.47 10.9 0.0 1.6 1 0 0 1 1 1 0 PilN biogenesis protein dimerization domain Methyltransf_31 PF13847.6 OQS03915.1 - 0.0054 16.5 0.1 0.012 15.5 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase domain INTS2 PF14750.6 OQS03915.1 - 0.018 12.6 0.8 0.025 12.2 0.8 1.1 1 0 0 1 1 1 0 Integrator complex subunit 2 Tis11B_N PF04553.12 OQS03915.1 - 0.041 14.4 0.1 4.2 7.9 0.1 2.5 2 1 0 2 2 2 0 Tis11B like protein, N terminus FAA_hydrolase_N PF09298.11 OQS03915.1 - 0.49 10.6 2.4 17 5.6 0.0 3.1 2 1 1 3 3 3 0 Fumarylacetoacetase N-terminal DUF3573 PF12097.8 OQS03915.1 - 0.54 9.0 3.6 0.79 8.5 3.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) SlyX PF04102.12 OQS03915.1 - 0.75 10.5 6.5 1.2 9.8 0.4 3.0 3 0 0 3 3 3 0 SlyX Laminin_G_3 PF13385.6 OQS03916.1 - 2.3e-05 24.6 0.1 0.00013 22.2 0.0 2.4 2 0 0 2 2 2 1 Concanavalin A-like lectin/glucanases superfamily Laminin_G_2 PF02210.24 OQS03916.1 - 0.0023 18.5 0.0 0.007 16.9 0.0 1.8 1 0 0 1 1 1 1 Laminin G domain Laminin_G_1 PF00054.23 OQS03916.1 - 0.005 17.1 0.0 0.011 16.0 0.0 1.4 1 0 0 1 1 1 1 Laminin G domain CUB PF00431.20 OQS03916.1 - 0.062 13.6 1.1 0.9 9.9 0.2 3.2 3 0 0 3 3 3 0 CUB domain DUF3223 PF11523.8 OQS03916.1 - 0.12 13.3 0.0 0.36 11.7 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3223) DnaJ-X PF14308.6 OQS03917.1 - 1.5e-35 122.6 12.2 1.4e-34 119.4 12.2 2.2 1 1 0 1 1 1 1 X-domain of DnaJ-containing DnaJ PF00226.31 OQS03917.1 - 6e-25 87.2 0.5 6e-25 87.2 0.5 2.4 3 0 0 3 3 3 1 DnaJ domain ATG_C PF09333.11 OQS03917.1 - 4.2e-05 23.8 0.2 0.00019 21.7 0.2 2.2 1 0 0 1 1 1 1 Autophagy-related protein C terminal domain Rtf2 PF04641.12 OQS03917.1 - 0.077 12.4 7.5 0.15 11.4 7.5 1.4 1 0 0 1 1 1 0 Rtf2 RING-finger Neur_chan_memb PF02932.16 OQS03917.1 - 0.092 12.8 0.8 0.14 12.2 0.8 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region XAP5 PF04921.14 OQS03917.1 - 0.92 9.3 10.5 1.7 8.4 10.5 1.4 1 0 0 1 1 1 0 XAP5, circadian clock regulator Presenilin PF01080.17 OQS03917.1 - 4.2 6.0 8.3 7.2 5.3 8.3 1.3 1 0 0 1 1 1 0 Presenilin Pkinase_Tyr PF07714.17 OQS03918.1 - 7e-53 179.5 0.0 8.7e-53 179.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OQS03918.1 - 4.7e-51 173.7 0.0 6.1e-51 173.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQS03919.1 - 1e-35 123.3 0.0 1.3e-35 123.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OQS03919.1 - 6.2e-31 107.7 0.0 7.5e-31 107.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 OQS03919.1 - 0.045 12.5 0.0 0.058 12.2 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase APH PF01636.23 OQS03919.1 - 0.071 13.0 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase_Tyr PF07714.17 OQS03921.1 - 1.6e-58 198.1 0.0 2e-58 197.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OQS03921.1 - 3.2e-52 177.5 0.0 4e-52 177.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Haspin_kinase PF12330.8 OQS03921.1 - 0.011 14.7 0.0 0.039 12.9 0.0 1.7 2 0 0 2 2 2 0 Haspin like kinase domain Pkinase_fungal PF17667.1 OQS03921.1 - 0.014 14.2 0.0 0.02 13.7 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase Kinase-like PF14531.6 OQS03921.1 - 0.028 13.8 0.0 0.078 12.3 0.0 1.6 1 1 1 2 2 2 0 Kinase-like Rimk_N PF18030.1 OQS03921.1 - 0.039 14.3 0.0 0.6 10.5 0.0 2.3 2 0 0 2 2 2 0 RimK PreATP-grasp domain APH PF01636.23 OQS03921.1 - 0.07 13.0 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase PF00069.25 OQS03922.1 - 1e-26 93.9 0.0 1.2e-26 93.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQS03922.1 - 1.8e-26 93.0 0.0 2.2e-26 92.7 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase TOBE_2 PF08402.10 OQS03922.1 - 0.19 11.9 0.0 0.37 11.0 0.0 1.5 1 0 0 1 1 1 0 TOBE domain Pkinase PF00069.25 OQS03923.1 - 0.2 11.0 0.0 0.82 9.0 0.0 1.7 2 0 0 2 2 2 0 Protein kinase domain Pkinase PF00069.25 OQS03924.1 - 1.7e-40 139.1 0.1 1.6e-26 93.3 0.0 3.0 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OQS03924.1 - 5.5e-39 134.0 0.0 2.5e-21 76.2 0.0 3.1 2 1 0 2 2 2 2 Protein tyrosine kinase APH PF01636.23 OQS03924.1 - 0.025 14.5 0.0 3.4 7.5 0.0 2.3 2 0 0 2 2 2 0 Phosphotransferase enzyme family IQ PF00612.27 OQS03925.1 - 0.0025 17.4 17.7 0.16 11.8 0.1 4.8 4 0 0 4 4 4 2 IQ calmodulin-binding motif LepA_C PF06421.12 OQS03925.1 - 0.0044 17.2 6.8 0.0044 17.2 6.8 2.1 2 0 0 2 2 2 1 GTP-binding protein LepA C-terminus DUF1689 PF07954.11 OQS03925.1 - 0.099 13.0 0.1 0.2 12.1 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1689) SPARC_Ca_bdg PF10591.9 OQS03925.1 - 0.13 12.6 1.6 0.41 11.0 1.6 1.8 1 0 0 1 1 1 0 Secreted protein acidic and rich in cysteine Ca binding region Zeta_toxin PF06414.12 OQS03926.1 - 3.8e-18 65.5 0.0 7.9e-18 64.4 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin ACT PF01842.25 OQS03926.1 - 1.4e-08 34.4 0.0 4e-08 32.9 0.0 1.8 1 0 0 1 1 1 1 ACT domain AAA_33 PF13671.6 OQS03926.1 - 7.3e-06 26.2 0.0 1.4e-05 25.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 OQS03926.1 - 7.5e-06 26.5 0.1 3.2e-05 24.5 0.1 2.1 1 1 0 1 1 1 1 AAA domain ACT_4 PF13291.6 OQS03926.1 - 0.0029 18.2 0.1 0.018 15.6 0.0 2.3 2 0 0 2 2 2 1 ACT domain AAA_16 PF13191.6 OQS03926.1 - 0.0082 16.5 0.0 0.026 14.9 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain CPT PF07931.12 OQS03926.1 - 0.012 15.4 0.0 0.031 14.1 0.0 1.7 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein AAA_17 PF13207.6 OQS03926.1 - 0.04 14.3 0.0 0.27 11.7 0.0 2.2 1 1 0 1 1 1 0 AAA domain Viral_helicase1 PF01443.18 OQS03926.1 - 0.046 13.4 0.0 1.4 8.6 0.0 2.4 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase DUF2666 PF10869.8 OQS03926.1 - 0.062 13.5 0.0 0.28 11.4 0.0 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF2666) AAA PF00004.29 OQS03926.1 - 0.15 12.4 0.0 1.7 9.1 0.0 2.3 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 OQS03926.1 - 0.15 12.2 0.0 0.51 10.6 0.0 1.9 2 0 0 2 2 2 0 AAA domain RabGAP-TBC PF00566.18 OQS03927.1 - 1.1e-13 51.3 0.8 1.7e-12 47.4 0.8 2.2 1 1 0 1 1 1 1 Rab-GTPase-TBC domain Tyrosinase PF00264.20 OQS03928.1 - 2.2e-12 47.7 0.1 2.9e-11 44.1 0.1 2.2 1 1 0 1 1 1 1 Common central domain of tyrosinase Zip PF02535.22 OQS03929.1 - 2.6e-54 184.7 28.3 5.5e-42 144.2 18.1 3.0 2 1 0 2 2 2 2 ZIP Zinc transporter HupE_UreJ PF04955.12 OQS03929.1 - 0.0089 15.5 6.2 0.0089 15.5 6.2 3.1 3 0 0 3 3 3 1 HupE / UreJ protein GCSF PF16647.5 OQS03929.1 - 0.014 15.3 0.4 0.052 13.4 0.1 2.1 1 1 1 2 2 2 0 Granulocyte colony-stimulating factor RhodobacterPufX PF11511.8 OQS03929.1 - 0.093 12.4 0.3 24 4.6 0.1 3.1 2 0 0 2 2 2 0 Intrinsic membrane protein PufX HORMA PF02301.18 OQS03930.1 - 5.1e-42 143.9 0.3 1e-41 142.9 0.3 1.5 1 0 0 1 1 1 1 HORMA domain FeoC PF09012.10 OQS03930.1 - 0.023 14.8 0.5 1.7 8.8 0.0 2.7 2 0 0 2 2 2 0 FeoC like transcriptional regulator HA PF03457.14 OQS03932.1 - 6.5e-22 77.6 1.7 7.6e-07 29.4 0.2 3.8 4 0 0 4 4 4 3 Helicase associated domain Ank_2 PF12796.7 OQS03933.1 - 1e-146 477.9 29.2 3.2e-18 66.1 0.1 12.7 2 2 10 13 13 13 13 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQS03933.1 - 8.7e-118 383.3 11.4 1.1e-10 41.8 0.2 16.5 8 4 6 16 16 16 16 Ankyrin repeats (many copies) Ank PF00023.30 OQS03933.1 - 1.1e-117 379.9 70.0 8.1e-06 26.1 0.2 24.5 22 3 2 24 24 24 23 Ankyrin repeat Ank_3 PF13606.6 OQS03933.1 - 2.1e-103 325.7 28.9 0.00015 22.0 0.1 24.3 24 0 0 24 24 24 22 Ankyrin repeat Ank_5 PF13857.6 OQS03933.1 - 4.8e-75 246.6 33.1 9e-07 29.1 0.0 16.6 7 4 8 17 17 17 17 Ankyrin repeats (many copies) Imm_superinfect PF14373.6 OQS03933.1 - 3.4e-05 23.7 9.9 16 5.6 0.0 9.5 9 0 0 9 9 9 1 Superinfection immunity protein DUF3447 PF11929.8 OQS03933.1 - 0.00012 22.0 0.1 1 9.3 0.0 5.5 6 0 0 6 6 6 1 Domain of unknown function (DUF3447) PK_C PF02887.16 OQS03933.1 - 0.0029 17.8 0.5 2.9 8.1 0.0 5.0 4 3 2 6 6 6 1 Pyruvate kinase, alpha/beta domain BRX_assoc PF16627.5 OQS03933.1 - 0.13 12.4 0.2 0.13 12.4 0.2 2.5 2 0 0 2 2 2 0 Unstructured region between BRX_N and BRX domain Arg_repressor PF01316.21 OQS03933.1 - 0.16 11.7 4.6 71 3.3 0.0 6.9 10 0 0 10 10 10 0 Arginine repressor, DNA binding domain DDE_3 PF13358.6 OQS03934.1 - 2.7e-07 30.5 0.0 4.3e-07 29.8 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease Acetyltransf_1 PF00583.25 OQS03935.1 - 4.2e-18 65.7 0.0 1.2e-17 64.3 0.0 1.8 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 OQS03935.1 - 4e-11 43.2 0.1 8.3e-11 42.2 0.1 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 OQS03935.1 - 4.4e-11 42.8 0.0 9.7e-11 41.7 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 OQS03935.1 - 1.1e-08 34.9 0.1 4.3e-08 33.0 0.1 1.9 2 0 0 2 2 2 1 FR47-like protein Acetyltransf_8 PF13523.6 OQS03935.1 - 8.4e-05 22.3 0.0 0.00021 21.0 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 OQS03935.1 - 0.0049 17.5 0.0 0.013 16.1 0.0 1.9 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF4468 PF14730.6 OQS03935.1 - 0.042 14.1 0.1 0.19 12.0 0.1 2.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4468) with TBP-like fold Acetyltransf_9 PF13527.7 OQS03935.1 - 0.044 13.9 0.0 0.12 12.5 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain PanZ PF12568.8 OQS03935.1 - 0.055 13.2 0.0 0.15 11.8 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain, PanZ MCM PF00493.23 OQS03936.1 - 3e-104 347.0 0.2 6.7e-104 345.9 0.2 1.6 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 OQS03936.1 - 2.4e-32 111.4 0.8 5.8e-32 110.2 0.8 1.7 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 OQS03936.1 - 1e-22 80.4 1.7 2.9e-22 78.9 1.7 1.9 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 OQS03936.1 - 4.8e-15 56.0 1.1 5.2e-14 52.7 0.1 2.6 2 0 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.21 OQS03936.1 - 2.4e-07 30.4 0.3 0.00014 21.3 0.0 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 OQS03936.1 - 1.6e-05 24.7 0.1 5.4e-05 23.1 0.1 2.0 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 OQS03936.1 - 4.5e-05 23.5 0.0 0.00015 21.7 0.0 2.0 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_lid_2 PF17863.1 OQS03936.1 - 0.02 14.8 0.8 0.069 13.0 0.1 2.2 2 0 0 2 2 2 0 AAA lid domain AAA_16 PF13191.6 OQS03936.1 - 0.02 15.2 0.3 0.081 13.3 0.1 2.1 1 1 1 2 2 2 0 AAA ATPase domain Sigma54_activat PF00158.26 OQS03936.1 - 0.025 14.3 0.2 1.7 8.3 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain Mg_chelatase_C PF13335.6 OQS03936.1 - 0.061 14.0 0.8 0.21 12.2 0.8 1.9 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI C-terminal RGS PF00615.19 OQS03937.1 - 5.5e-06 26.6 4.2 6.1e-06 26.5 0.6 2.4 2 1 0 2 2 2 1 Regulator of G protein signaling domain Peptidase_C54 PF03416.19 OQS03937.1 - 0.047 13.1 0.1 0.055 12.9 0.1 1.2 1 0 0 1 1 1 0 Peptidase family C54 Glyco_transf_24 PF18404.1 OQS03937.1 - 0.078 12.4 0.3 0.37 10.1 0.1 1.9 2 0 0 2 2 2 0 Glucosyltransferase 24 tRNA-synt_His PF13393.6 OQS03938.1 - 1.9e-45 155.5 5.6 2.2e-45 155.3 0.0 2.5 2 0 0 2 2 2 1 Histidyl-tRNA synthetase Lyase_aromatic PF00221.19 OQS03938.1 - 3.6e-39 134.7 10.2 6.3e-39 133.9 10.2 1.3 1 0 0 1 1 1 1 Aromatic amino acid lyase HGTP_anticodon PF03129.20 OQS03938.1 - 2e-12 47.1 0.0 4.9e-12 45.8 0.0 1.7 1 0 0 1 1 1 1 Anticodon binding domain HGTP_anticodon2 PF12745.7 OQS03938.1 - 1.2e-05 25.0 0.1 1.2e-05 25.0 0.1 1.6 2 0 0 2 2 2 1 Anticodon binding domain of tRNAs RSN1_7TM PF02714.15 OQS03938.1 - 1.7e-05 24.3 14.2 1.7e-05 24.3 14.2 2.2 2 1 0 2 2 2 1 Calcium-dependent channel, 7TM region, putative phosphate tRNA-synt_2 PF00152.20 OQS03938.1 - 0.0013 17.9 0.1 0.0029 16.7 0.0 1.6 2 0 0 2 2 2 1 tRNA synthetases class II (D, K and N) PHM7_cyt PF14703.6 OQS03938.1 - 0.0022 18.3 6.1 0.003 17.8 0.3 2.9 3 0 0 3 3 3 1 Cytosolic domain of 10TM putative phosphate transporter Ank_2 PF12796.7 OQS03939.1 - 4.2e-16 59.3 0.7 9.3e-16 58.2 0.5 1.6 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OQS03939.1 - 5.3e-15 55.3 0.8 1.5e-07 31.5 0.0 2.6 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 OQS03939.1 - 5.9e-14 52.2 0.1 6e-08 33.1 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 OQS03939.1 - 2.7e-13 49.7 4.4 0.0015 18.9 0.2 4.0 3 1 1 4 4 4 3 Ankyrin repeat Ank_3 PF13606.6 OQS03939.1 - 2e-12 46.1 0.1 0.00098 19.4 0.0 4.2 4 0 0 4 4 4 2 Ankyrin repeat DUF3978 PF13123.6 OQS03939.1 - 0.071 12.9 0.0 0.099 12.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3978) HSP70 PF00012.20 OQS03940.1 - 1.3e-130 436.5 11.3 4e-129 431.5 11.3 2.2 1 1 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 OQS03940.1 - 1e-06 27.8 1.0 2.2e-06 26.7 0.0 2.0 2 1 1 3 3 3 1 MreB/Mbl protein LytR_cpsA_psr PF03816.14 OQS03940.1 - 0.00013 22.2 0.1 0.00086 19.5 0.1 2.2 2 0 0 2 2 2 1 Cell envelope-related transcriptional attenuator domain Orbi_VP6 PF01516.16 OQS03940.1 - 0.93 9.0 8.4 0.13 11.7 4.2 1.7 2 0 0 2 2 2 0 Orbivirus helicase VP6 GEN1_C PF18380.1 OQS03940.1 - 1.2 10.1 7.6 1 10.3 4.3 2.5 2 0 0 2 2 2 0 Holliday junction resolvase Gen1 C-terminal domain CAP_GLY PF01302.25 OQS03941.1 - 2.2e-24 85.3 1.0 3.5e-24 84.6 1.0 1.3 1 0 0 1 1 1 1 CAP-Gly domain DUF240 PF03086.14 OQS03941.1 - 0.23 11.4 8.5 0.44 10.5 0.2 3.6 3 0 0 3 3 3 0 Domain of unknown function (DUF240) Fez1 PF06818.15 OQS03941.1 - 2 8.8 87.9 0.36 11.3 10.6 6.3 2 2 4 6 6 6 0 Fez1 Myb_DNA-binding PF00249.31 OQS03942.1 - 1.6e-11 44.2 0.0 4.5e-11 42.8 0.0 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain SWIRM PF04433.17 OQS03942.1 - 1.8e-06 28.2 0.0 5.1e-06 26.7 0.0 1.8 1 0 0 1 1 1 1 SWIRM domain Myb_DNA-bind_6 PF13921.6 OQS03942.1 - 9.1e-06 25.8 0.0 2.1e-05 24.7 0.0 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain WW PF00397.26 OQS03943.1 - 2.7e-07 30.6 3.2 3.8e-07 30.1 2.0 1.9 2 0 0 2 2 2 1 WW domain Ank_2 PF12796.7 OQS03944.1 - 1.1e-48 163.8 21.2 3.1e-14 53.3 0.6 6.9 4 1 4 8 8 8 8 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OQS03944.1 - 8.1e-33 112.1 15.0 3.7e-09 36.7 0.2 10.3 4 3 5 10 10 10 7 Ankyrin repeats (many copies) Ank_4 PF13637.6 OQS03944.1 - 5.8e-31 106.5 5.2 8.4e-05 23.1 0.0 9.7 6 2 3 9 9 9 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQS03944.1 - 9.2e-28 93.2 15.3 0.0039 17.6 0.0 11.8 12 0 0 12 12 12 7 Ankyrin repeat Ank PF00023.30 OQS03944.1 - 1.3e-24 85.5 19.4 0.0051 17.2 0.0 10.7 11 0 0 11 11 11 6 Ankyrin repeat PKD_channel PF08016.12 OQS03944.1 - 0.0022 16.8 11.5 0.0022 16.8 11.5 2.5 3 0 0 3 3 3 1 Polycystin cation channel YojJ PF10372.9 OQS03944.1 - 1.7 8.8 5.4 9.8 6.4 5.4 2.4 1 0 0 1 1 1 0 Bacterial membrane-spanning protein N-terminus RVT_3 PF13456.6 OQS03945.1 - 1.8e-06 27.8 0.1 0.00017 21.4 0.1 2.2 1 1 0 1 1 1 1 Reverse transcriptase-like Lipase_3 PF01764.25 OQS03946.1 - 2.5e-10 40.4 0.0 5.3e-10 39.3 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) Ank_5 PF13857.6 OQS03946.1 - 2.5e-07 30.8 3.4 0.11 12.9 0.0 5.7 4 1 1 5 5 5 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 OQS03946.1 - 6.6e-07 29.8 4.0 0.17 12.5 0.3 5.8 6 0 0 6 6 5 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 OQS03946.1 - 8.4e-07 29.5 3.3 0.011 16.3 0.1 4.5 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) DFP PF04127.15 OQS03946.1 - 3.3e-05 23.8 0.0 0.003 17.4 0.0 2.6 2 0 0 2 2 2 1 DNA / pantothenate metabolism flavoprotein Glyco_hydro_17 PF00332.18 OQS03946.1 - 0.0039 16.8 2.4 0.008 15.8 1.7 1.8 2 0 0 2 2 2 1 Glycosyl hydrolases family 17 Thioesterase PF00975.20 OQS03946.1 - 0.0048 17.0 0.1 0.01 16.0 0.1 1.5 1 0 0 1 1 1 1 Thioesterase domain RVT_3 PF13456.6 OQS03946.1 - 0.0089 15.8 0.0 0.024 14.4 0.0 1.7 1 0 0 1 1 1 1 Reverse transcriptase-like Ank_3 PF13606.6 OQS03946.1 - 0.0095 16.4 0.2 52 4.9 0.0 5.2 5 0 0 5 5 5 0 Ankyrin repeat RNase_H PF00075.24 OQS03946.1 - 0.033 14.4 0.0 0.087 13.0 0.0 1.7 1 0 0 1 1 1 0 RNase H Glyco_hydro_53 PF07745.13 OQS03946.1 - 0.1 11.5 0.0 0.18 10.8 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase family 53 VMA21 PF09446.10 OQS03947.1 - 2.2e-15 56.5 2.8 2.6e-15 56.2 2.8 1.1 1 0 0 1 1 1 1 VMA21-like domain JAB PF01398.21 OQS03948.1 - 1.7e-15 57.0 0.0 4.6e-15 55.6 0.0 1.8 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease USP8_dimer PF08969.11 OQS03948.1 - 7.6e-07 29.3 4.1 8.9e-07 29.1 2.1 2.2 2 0 0 2 2 2 1 USP8 dimerisation domain Prok-JAB PF14464.6 OQS03948.1 - 9.8e-05 22.1 0.0 0.00032 20.5 0.0 1.8 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain Myb_DNA-binding PF00249.31 OQS03948.1 - 0.013 15.6 0.2 0.039 14.2 0.2 1.9 1 0 0 1 1 1 0 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OQS03948.1 - 0.076 13.3 0.9 0.18 12.1 0.1 2.1 2 0 0 2 2 2 0 Myb-like DNA-binding domain PX PF00787.24 OQS03950.1 - 6.7e-20 71.2 0.0 7.3e-20 71.1 0.0 1.0 1 0 0 1 1 1 1 PX domain Beta-lactamase PF00144.24 OQS03951.1 - 1.1e-48 166.2 0.0 1.5e-48 165.7 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase Thioredoxin_11 PF18078.1 OQS03952.1 - 0.017 15.2 0.0 0.023 14.8 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin-like SNTX domain Methyltr_RsmB-F PF01189.17 OQS03953.1 - 1.9e-27 96.2 0.0 1.7e-16 60.5 0.0 2.2 1 1 1 2 2 2 2 16S rRNA methyltransferase RsmB/F Methyltransf_31 PF13847.6 OQS03953.1 - 3e-07 30.3 0.0 4.2e-05 23.4 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 OQS03953.1 - 3.2e-06 27.7 0.0 2.8e-05 24.7 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain PCMT PF01135.19 OQS03953.1 - 0.00018 21.3 0.0 0.00055 19.8 0.0 1.7 2 0 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) FtsJ PF01728.19 OQS03953.1 - 0.00021 21.4 0.0 0.002 18.2 0.0 2.1 1 1 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_23 PF13489.6 OQS03953.1 - 0.00061 19.7 0.0 0.0019 18.1 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 OQS03953.1 - 0.0063 15.9 0.0 0.044 13.1 0.0 2.0 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.12 OQS03953.1 - 0.0074 16.9 0.0 0.6 10.8 0.0 2.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 OQS03953.1 - 0.03 15.1 0.1 1.4 9.7 0.0 2.6 2 1 0 2 2 2 0 Methyltransferase domain Big_11 PF18200.1 OQS03953.1 - 0.054 13.4 0.0 0.19 11.6 0.0 1.9 2 0 0 2 2 2 0 Bacterial Ig-like domain Fibrillarin PF01269.17 OQS03953.1 - 0.074 12.1 0.1 0.17 11.0 0.1 1.6 1 0 0 1 1 1 0 Fibrillarin AAA PF00004.29 OQS03954.1 - 6.4e-38 130.2 0.0 1.5e-37 129.0 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 OQS03954.1 - 1.8e-10 40.4 0.0 9.8e-10 38.1 0.0 2.3 2 1 0 2 2 2 1 AAA+ lid domain AAA_2 PF07724.14 OQS03954.1 - 1.2e-07 32.0 0.0 2.4e-07 31.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) Vps4_C PF09336.10 OQS03954.1 - 7.9e-06 25.8 0.0 2.5e-05 24.2 0.0 2.0 1 0 0 1 1 1 1 Vps4 C terminal oligomerisation domain AAA_5 PF07728.14 OQS03954.1 - 2.5e-05 24.3 0.2 0.00026 21.0 0.2 2.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 OQS03954.1 - 2.5e-05 24.1 0.0 0.0001 22.1 0.0 2.0 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 OQS03954.1 - 0.0017 18.6 0.1 0.024 14.9 0.1 2.5 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 OQS03954.1 - 0.0026 18.1 0.1 0.0059 17.0 0.1 1.6 1 1 0 1 1 1 1 AAA ATPase domain IstB_IS21 PF01695.17 OQS03954.1 - 0.0038 17.0 0.0 0.0092 15.7 0.0 1.7 1 0 0 1 1 1 1 IstB-like ATP binding protein Mg_chelatase PF01078.21 OQS03954.1 - 0.0062 15.9 0.0 0.012 15.0 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_7 PF12775.7 OQS03954.1 - 0.0073 15.8 0.1 0.029 13.9 0.1 2.0 1 1 0 1 1 1 1 P-loop containing dynein motor region AAA_33 PF13671.6 OQS03954.1 - 0.0086 16.2 0.0 0.016 15.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.6 OQS03954.1 - 0.01 15.9 0.0 0.028 14.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain TIP49 PF06068.13 OQS03954.1 - 0.022 14.0 0.0 0.044 13.0 0.0 1.4 1 0 0 1 1 1 0 TIP49 P-loop domain RNA_helicase PF00910.22 OQS03954.1 - 0.028 14.8 0.0 0.088 13.2 0.0 1.9 1 1 0 1 1 1 0 RNA helicase Parvo_NS1 PF01057.17 OQS03954.1 - 0.028 13.5 0.0 0.052 12.6 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 DUF815 PF05673.13 OQS03954.1 - 0.029 13.6 0.0 0.054 12.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) TsaE PF02367.17 OQS03954.1 - 0.04 13.9 0.0 0.099 12.7 0.0 1.6 2 0 0 2 2 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Bac_DnaA PF00308.18 OQS03954.1 - 0.046 13.5 0.5 0.39 10.5 0.0 2.4 2 1 0 2 2 1 0 Bacterial dnaA protein AAA_18 PF13238.6 OQS03954.1 - 0.058 13.9 0.0 0.16 12.6 0.0 1.9 1 0 0 1 1 1 0 AAA domain MCM PF00493.23 OQS03954.1 - 0.082 12.0 0.0 0.15 11.1 0.0 1.4 1 0 0 1 1 1 0 MCM P-loop domain AAA_3 PF07726.11 OQS03954.1 - 0.1 12.4 0.1 0.42 10.5 0.0 2.1 3 0 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 OQS03954.1 - 0.12 11.8 0.0 0.28 10.6 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein AAA_30 PF13604.6 OQS03954.1 - 0.12 12.0 0.0 0.26 11.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 OQS03954.1 - 0.13 12.0 0.0 0.24 11.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 OQS03954.1 - 0.14 12.4 0.0 0.26 11.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain DDE_Tnp_1_7 PF13843.6 OQS03955.1 - 0.2 10.9 0.0 0.2 10.9 0.0 1.0 1 0 0 1 1 1 0 Transposase IS4 Zmiz1_N PF18028.1 OQS03957.1 - 0.015 15.6 1.1 0.86 10.0 0.0 3.0 3 0 0 3 3 3 0 Zmiz1 N-terminal tetratricopeptide repeat domain HlyE PF06109.13 OQS03959.1 - 3e-05 23.5 0.0 5.8e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 Haemolysin E (HlyE) DUF4419 PF14388.6 OQS03960.1 - 1.5e-101 339.9 0.2 1.8e-101 339.6 0.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4419) Acyl_transf_3 PF01757.22 OQS03961.1 - 7.3e-08 31.9 3.5 7.7e-08 31.8 3.5 1.0 1 0 0 1 1 1 1 Acyltransferase family HlyE PF06109.13 OQS03962.1 - 2.2e-37 129.0 5.5 2.8e-37 128.7 5.5 1.0 1 0 0 1 1 1 1 Haemolysin E (HlyE) Prefoldin_2 PF01920.20 OQS03962.1 - 0.067 13.2 1.0 0.17 11.8 0.1 2.1 2 0 0 2 2 2 0 Prefoldin subunit BLOC1_2 PF10046.9 OQS03962.1 - 1 9.7 7.3 5.7 7.3 0.5 3.7 3 1 1 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Cnd3 PF12719.7 OQS03964.1 - 4.1e-28 98.4 2.0 1e-27 97.1 2.0 1.7 1 0 0 1 1 1 1 Nuclear condensing complex subunits, C-term domain HEAT_2 PF13646.6 OQS03964.1 - 0.00029 21.2 1.0 0.33 11.4 0.4 3.3 2 0 0 2 2 2 2 HEAT repeats CCDC-167 PF15188.6 OQS03964.1 - 0.0067 16.7 0.7 0.0067 16.7 0.7 2.6 2 0 0 2 2 2 1 Coiled-coil domain-containing protein 167 DUF5420 PF17457.2 OQS03964.1 - 0.015 15.2 0.0 0.043 13.7 0.0 1.8 1 0 0 1 1 1 0 Family of unknown function (DUF5420) RTP1_C1 PF10363.9 OQS03964.1 - 0.089 13.0 0.2 5.5 7.2 0.1 3.5 3 0 0 3 3 3 0 Required for nuclear transport of RNA pol II C-terminus 1 HEAT PF02985.22 OQS03964.1 - 0.34 11.3 2.7 23 5.6 0.1 4.3 4 0 0 4 4 4 0 HEAT repeat ABC_tran PF00005.27 OQS03965.1 - 1.4e-16 61.3 0.0 3.6e-16 59.9 0.0 1.7 1 1 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 OQS03965.1 - 8.4e-07 29.1 0.2 0.018 14.9 0.0 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 OQS03965.1 - 0.0011 18.5 0.1 0.2 11.0 0.0 2.1 1 1 1 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 OQS03965.1 - 0.0013 18.5 0.1 0.0026 17.5 0.1 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_24 PF13479.6 OQS03965.1 - 0.035 13.8 0.0 0.044 13.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 OQS03965.1 - 0.065 13.7 0.1 0.16 12.5 0.1 1.6 2 0 0 2 2 2 0 AAA domain Arf PF00025.21 OQS03965.1 - 0.07 12.6 0.0 0.13 11.7 0.0 1.4 1 0 0 1 1 1 0 ADP-ribosylation factor family RsgA_GTPase PF03193.16 OQS03965.1 - 0.097 12.6 0.2 0.16 11.8 0.2 1.3 1 0 0 1 1 1 0 RsgA GTPase NYN_YacP PF05991.11 OQS03965.1 - 0.12 12.4 0.0 0.19 11.7 0.0 1.3 1 0 0 1 1 1 0 YacP-like NYN domain AAA_16 PF13191.6 OQS03965.1 - 0.12 12.8 0.0 0.15 12.4 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain AAA_28 PF13521.6 OQS03965.1 - 0.13 12.5 0.0 0.19 11.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 OQS03965.1 - 0.18 11.8 0.0 3.7 7.6 0.0 2.2 2 0 0 2 2 2 0 AAA domain G-alpha PF00503.20 OQS03965.1 - 0.21 10.7 0.1 0.3 10.2 0.1 1.2 1 0 0 1 1 1 0 G-protein alpha subunit Zeta_toxin PF06414.12 OQS03965.1 - 0.22 10.8 0.3 0.42 9.9 0.2 1.4 1 1 0 1 1 1 0 Zeta toxin AAA_15 PF13175.6 OQS03965.1 - 0.23 11.1 0.1 0.38 10.4 0.1 1.2 1 0 0 1 1 1 0 AAA ATPase domain PP2C PF00481.21 OQS03966.1 - 5.5e-51 173.7 0.0 8.8e-51 173.0 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C GlcNAc PF11397.8 OQS03966.1 - 1.1e-47 163.3 0.1 4.5e-38 131.6 0.2 2.5 1 1 1 2 2 2 2 Glycosyltransferase (GlcNAc) ABC_membrane PF00664.23 OQS03967.1 - 1.7e-26 93.5 10.4 2.3e-26 93.1 10.4 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 OQS03967.1 - 1.1e-22 81.1 0.0 2.3e-22 80.0 0.0 1.6 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 OQS03967.1 - 1.8e-05 24.3 2.9 0.0019 17.7 0.4 2.2 1 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 OQS03967.1 - 0.0066 16.5 0.1 0.018 15.1 0.1 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase IstB_IS21 PF01695.17 OQS03967.1 - 0.02 14.6 0.2 0.56 9.9 0.0 2.4 2 0 0 2 2 2 0 IstB-like ATP binding protein DEAD PF00270.29 OQS03967.1 - 0.11 12.3 0.0 0.27 11.0 0.0 1.6 1 0 0 1 1 1 0 DEAD/DEAH box helicase V_ATPase_I PF01496.19 OQS03968.1 - 6.2e-76 256.0 0.0 7.6e-76 255.7 0.0 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family FYVE PF01363.21 OQS03969.1 - 5.5e-09 36.0 11.3 1.4e-08 34.7 11.3 1.7 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.16 OQS03969.1 - 1.8e-07 31.4 6.5 4.1e-07 30.2 6.5 1.5 1 0 0 1 1 1 1 FYVE-type zinc finger zf-RING_2 PF13639.6 OQS03969.1 - 0.7 10.3 10.9 2 8.8 10.9 1.8 1 0 0 1 1 1 0 Ring finger domain zf-Dof PF02701.15 OQS03969.1 - 1.9 8.7 8.9 5.9 7.1 8.9 1.9 1 1 0 1 1 1 0 Dof domain, zinc finger DctM PF06808.12 OQS03970.1 - 0.0013 17.6 1.3 0.0017 17.3 1.3 1.1 1 0 0 1 1 1 1 Tripartite ATP-independent periplasmic transporter, DctM component Rick_17kDa_Anti PF05433.15 OQS03970.1 - 0.0038 17.0 0.2 0.0063 16.3 0.2 1.3 1 0 0 1 1 1 1 Glycine zipper 2TM domain DUF5345 PF17280.2 OQS03970.1 - 0.014 15.4 0.1 0.033 14.2 0.0 1.6 2 0 0 2 2 2 0 Family of unknown function (DUF5345) Gly-zipper_Omp PF13488.6 OQS03970.1 - 0.035 14.1 4.7 0.058 13.4 4.7 1.4 1 1 0 1 1 1 0 Glycine zipper FYVE PF01363.21 OQS03971.1 - 5.4e-16 58.5 9.6 1e-15 57.6 9.6 1.5 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.16 OQS03971.1 - 0.025 14.8 5.6 0.077 13.2 5.6 1.8 2 0 0 2 2 2 0 FYVE-type zinc finger CagY_M PF07337.11 OQS03971.1 - 0.042 13.5 1.7 0.34 10.6 0.1 2.5 2 0 0 2 2 2 0 DC-EC Repeat Prot_ATP_ID_OB PF16450.5 OQS03972.1 - 0.051 13.5 0.0 0.12 12.4 0.0 1.7 1 0 0 1 1 1 0 Proteasomal ATPase OB C-terminal domain HAD_2 PF13419.6 OQS03972.1 - 0.073 13.1 0.5 13 5.9 0.0 3.5 3 1 2 5 5 5 0 Haloacid dehalogenase-like hydrolase CSRNP_N PF16019.5 OQS03973.1 - 4.1e-06 26.9 0.1 6.2e-06 26.3 0.1 1.3 1 0 0 1 1 1 1 Cysteine/serine-rich nuclear protein N-terminus DUF4130 PF13566.6 OQS03973.1 - 0.087 12.9 0.0 0.18 11.8 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4130 PBAN PF05874.11 OQS03973.1 - 0.096 12.6 0.0 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 Pheromone biosynthesis activating neuropeptide (PBAN) Get5_C PF18514.1 OQS03974.1 - 0.015 15.0 1.0 0.023 14.4 0.1 1.8 2 0 0 2 2 2 0 Get5 C-terminal domain RRM_1 PF00076.22 OQS03976.1 - 2e-13 49.9 0.0 3.7e-13 49.1 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MutS_III PF05192.18 OQS03977.1 - 0.044 14.0 4.5 15 5.8 0.0 4.9 3 2 0 3 3 3 0 MutS domain III Csc2 PF18320.1 OQS03977.1 - 7 5.5 7.2 4.4 6.2 0.5 2.4 2 0 0 2 2 2 0 Csc2 Crispr Sulfatase_C PF14707.6 OQS03977.1 - 8.6 7.1 7.6 7.3 7.4 0.0 3.6 4 0 0 4 4 4 0 C-terminal region of aryl-sulfatase Cation_efflux PF01545.21 OQS03978.1 - 9.8e-48 162.5 0.6 1.4e-47 162.0 0.6 1.1 1 0 0 1 1 1 1 Cation efflux family Zip PF02535.22 OQS03978.1 - 0.00019 20.8 7.7 0.00019 20.8 7.7 1.6 2 0 0 2 2 2 1 ZIP Zinc transporter DUF4834 PF16118.5 OQS03978.1 - 0.25 12.3 0.9 0.6 11.1 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) CPL PF08144.11 OQS03979.1 - 0.099 13.0 0.1 0.18 12.2 0.1 1.4 1 0 0 1 1 1 0 CPL (NUC119) domain MORN PF02493.20 OQS03980.1 - 9.6e-53 173.1 75.8 2.3e-07 30.3 0.8 11.4 11 0 0 11 11 11 11 MORN repeat CTP_transf_1 PF01148.20 OQS03981.1 - 2.9e-45 155.1 13.2 4.3e-45 154.6 13.2 1.2 1 0 0 1 1 1 1 Cytidylyltransferase family CarS-like PF01864.17 OQS03981.1 - 0.0097 15.9 0.0 0.025 14.6 0.0 1.7 1 0 0 1 1 1 1 CDP-archaeol synthase EGF_CA PF07645.15 OQS03981.1 - 0.3 11.3 2.0 0.52 10.6 0.0 2.3 2 0 0 2 2 2 0 Calcium-binding EGF domain Sporozoite_P67 PF05642.11 OQS03981.1 - 0.93 7.5 13.4 1.3 7.0 13.4 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DNA_pol_phi PF04931.13 OQS03981.1 - 5.3 5.0 4.1 7.4 4.5 4.1 1.1 1 0 0 1 1 1 0 DNA polymerase phi TFIIF_alpha PF05793.12 OQS03981.1 - 9 4.8 6.1 12 4.3 6.1 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) LCM PF04072.14 OQS03983.1 - 4.4e-27 95.3 0.0 2.3e-26 92.9 0.0 2.0 1 1 0 1 1 1 1 Leucine carboxyl methyltransferase Acetyltransf_1 PF00583.25 OQS03983.1 - 2.1e-18 66.7 0.0 5e-18 65.4 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 OQS03983.1 - 8e-13 48.4 0.0 1.6e-12 47.5 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 OQS03983.1 - 1e-11 45.1 0.0 2.3e-11 44.0 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 OQS03983.1 - 1.4e-05 25.3 0.0 4e-05 23.8 0.0 1.8 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 OQS03983.1 - 0.0046 16.9 0.0 0.011 15.7 0.0 1.6 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 OQS03983.1 - 0.0058 16.7 0.1 0.025 14.7 0.1 2.1 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain PanZ PF12568.8 OQS03983.1 - 0.022 14.5 0.0 0.04 13.6 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain, PanZ Acetyltransf_CG PF14542.6 OQS03983.1 - 0.037 14.2 0.0 0.089 12.9 0.0 1.6 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase MeaB PF03308.16 OQS03983.1 - 0.19 10.7 0.0 0.31 10.0 0.0 1.2 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Moricin PF06451.11 OQS03985.1 - 0.11 12.2 0.1 0.24 11.2 0.1 1.6 1 1 0 1 1 1 0 Moricin NTP_transf_2 PF01909.23 OQS03986.1 - 6.5e-09 36.0 0.0 2.1e-08 34.4 0.0 1.9 1 1 0 1 1 1 1 Nucleotidyltransferase domain Polbeta PF18765.1 OQS03986.1 - 0.0026 17.8 0.0 0.0061 16.6 0.0 1.7 2 0 0 2 2 2 1 Polymerase beta, Nucleotidyltransferase PAP_assoc PF03828.19 OQS03986.1 - 0.016 15.4 0.0 0.029 14.6 0.0 1.5 1 0 0 1 1 1 0 Cid1 family poly A polymerase PKD_channel PF08016.12 OQS03987.1 - 0.0023 16.7 15.5 0.0023 16.7 15.5 2.7 1 1 0 2 2 2 1 Polycystin cation channel Ion_trans PF00520.31 OQS03987.1 - 0.0053 16.0 26.6 0.026 13.7 25.6 2.4 1 1 1 2 2 2 1 Ion transport protein RseC_MucC PF04246.12 OQS03987.1 - 4.7 7.2 7.9 0.76 9.7 0.2 3.1 3 1 0 3 3 3 0 Positive regulator of sigma(E), RseC/MucC Ank_2 PF12796.7 OQS03988.1 - 1.3e-23 83.4 1.5 2.3e-06 28.1 0.0 5.4 4 2 0 5 5 5 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQS03988.1 - 4.6e-21 74.9 4.7 4.3e-05 24.0 0.0 8.0 6 2 0 7 7 7 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 OQS03988.1 - 8.4e-13 48.3 7.4 0.67 10.4 0.0 9.5 6 2 5 11 11 11 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQS03988.1 - 3.9e-10 39.1 4.1 14 6.7 0.0 9.5 11 0 0 11 11 11 1 Ankyrin repeat Ank PF00023.30 OQS03988.1 - 3.1e-06 27.4 1.7 5.6 7.6 0.4 6.3 4 3 1 5 5 5 2 Ankyrin repeat ColG_sub PF18496.1 OQS03988.1 - 0.044 13.9 0.1 0.85 9.8 0.1 2.3 2 0 0 2 2 2 0 Collagenase G catalytic helper subdomain zf-TAZ PF02135.16 OQS03989.1 - 1.9e-36 124.4 70.8 1.1e-12 48.2 19.9 3.5 3 0 0 3 3 3 3 TAZ zinc finger KIX_2 PF16987.5 OQS03989.1 - 1.2e-15 57.3 4.6 1.2e-08 34.8 0.1 3.8 4 0 0 4 4 4 2 KIX domain KIX PF02172.16 OQS03989.1 - 9.1e-09 35.5 0.8 0.0035 17.6 0.2 2.9 2 0 0 2 2 2 2 KIX domain zf_CCCH_4 PF18345.1 OQS03989.1 - 1.4 9.1 4.4 0.43 10.7 1.1 2.0 2 0 0 2 2 2 0 Zinc finger domain Filamin PF00630.19 OQS03990.1 - 1.2e-45 154.6 0.4 5.7e-10 39.9 0.0 7.8 8 0 0 8 8 8 5 Filamin/ABP280 repeat PA14 PF07691.12 OQS03990.1 - 5.6e-17 61.9 1.5 5.3e-12 45.8 0.1 4.1 3 1 0 3 3 3 2 PA14 domain Invasin_D3 PF09134.10 OQS03990.1 - 5.7e-10 39.4 20.7 0.017 15.4 0.1 6.6 6 0 0 6 6 6 4 Invasin, domain 3 Calx-beta PF03160.14 OQS03990.1 - 0.0016 18.5 0.0 0.0037 17.4 0.0 1.5 1 0 0 1 1 1 1 Calx-beta domain EGF_2 PF07974.13 OQS03990.1 - 0.0055 17.0 43.8 0.0057 17.0 10.7 3.7 3 0 0 3 3 3 2 EGF-like domain Laminin_EGF PF00053.24 OQS03990.1 - 0.0079 16.3 9.8 0.0079 16.3 9.8 3.8 2 1 1 3 3 3 2 Laminin EGF domain Neurexophilin PF06312.12 OQS03990.1 - 0.035 13.6 7.1 5.6 6.4 0.3 3.8 4 0 0 4 4 4 0 Neurexophilin Big_9 PF17963.1 OQS03990.1 - 1.6 9.5 7.4 1 10.1 2.2 3.6 2 0 0 2 2 2 0 Bacterial Ig domain Frataxin_Cyay PF01491.16 OQS03992.1 - 2.3e-28 98.4 0.1 8.1e-28 96.6 0.0 2.0 2 0 0 2 2 2 1 Frataxin-like domain bZIP_1 PF00170.21 OQS03992.1 - 0.027 14.6 5.6 0.027 14.6 5.6 1.7 2 0 0 2 2 2 0 bZIP transcription factor DUF327 PF03885.13 OQS03992.1 - 0.066 13.2 0.6 0.066 13.2 0.6 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF327) SesA PF17107.5 OQS03992.1 - 0.26 11.5 0.9 21 5.3 0.0 2.6 2 0 0 2 2 2 0 N-terminal domain on NACHT_NTPase and P-loop NTPases CREPT PF16566.5 OQS03992.1 - 0.59 10.3 4.6 0.11 12.6 1.1 1.8 2 0 0 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour bZIP_2 PF07716.15 OQS03992.1 - 0.72 10.0 6.4 2 8.6 6.4 1.7 1 0 0 1 1 1 0 Basic region leucine zipper PhoLip_ATPase_C PF16212.5 OQS03993.1 - 6.7e-63 212.7 19.5 6.7e-63 212.7 19.5 3.1 4 0 0 4 4 4 1 Phospholipid-translocating P-type ATPase C-terminal Cation_ATPase PF13246.6 OQS03993.1 - 8.5e-16 57.8 0.0 8.6e-15 54.6 0.0 2.3 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 OQS03993.1 - 2.5e-13 50.8 0.4 1.2e-07 32.2 0.1 3.2 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase PhoLip_ATPase_N PF16209.5 OQS03993.1 - 2.3e-11 43.2 0.2 8e-11 41.5 0.2 1.9 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal E1-E2_ATPase PF00122.20 OQS03993.1 - 7e-08 32.2 0.3 3.1e-07 30.1 0.0 2.3 2 0 0 2 2 2 1 E1-E2 ATPase HAD PF12710.7 OQS03993.1 - 9.7e-05 22.9 0.0 0.64 10.4 0.0 2.4 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 OQS03993.1 - 0.0021 17.9 0.0 0.0053 16.5 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase NKAIN PF05640.14 OQS03993.1 - 0.11 11.7 7.4 0.29 10.3 7.4 1.7 1 0 0 1 1 1 0 Na,K-Atpase Interacting protein HTH_Tnp_1 PF01527.20 OQS03993.1 - 0.23 11.8 0.8 1.9 8.8 0.2 2.6 3 0 0 3 3 3 0 Transposase DUF2208 PF09973.9 OQS03993.1 - 3.2 7.3 8.8 0.75 9.4 0.3 3.3 3 0 0 3 3 3 0 Predicted membrane protein (DUF2208) PHM7_cyt PF14703.6 OQS03994.1 - 6e-06 26.6 0.2 1.2e-05 25.7 0.2 1.6 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter RSN1_7TM PF02714.15 OQS03994.1 - 7.1e-06 25.5 22.6 9.3e-06 25.1 15.0 3.4 2 1 0 2 2 2 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 OQS03994.1 - 0.0028 17.4 4.6 0.029 14.1 0.1 3.5 3 0 0 3 3 3 1 Late exocytosis, associated with Golgi transport Methyltr_RsmB-F PF01189.17 OQS03995.1 - 2.1e-41 141.8 0.1 3.9e-40 137.7 0.1 2.1 1 1 0 1 1 1 1 16S rRNA methyltransferase RsmB/F zf-CCHC_2 PF13696.6 OQS03995.1 - 2e-05 24.3 5.0 4e-05 23.3 5.0 1.4 1 0 0 1 1 1 1 Zinc knuckle FtsJ PF01728.19 OQS03995.1 - 7.8e-05 22.9 0.0 0.00025 21.2 0.0 2.0 1 1 0 1 1 1 1 FtsJ-like methyltransferase WD40 PF00400.32 OQS03996.1 - 1.5e-42 142.7 24.3 2.9e-08 34.3 0.4 8.5 8 0 0 8 8 8 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OQS03996.1 - 3.2e-26 91.5 3.6 7.1e-06 26.2 0.0 6.9 2 2 4 7 7 7 5 Anaphase-promoting complex subunit 4 WD40 domain LisH PF08513.11 OQS03996.1 - 2.9e-10 39.7 0.5 6.7e-10 38.6 0.2 1.8 2 0 0 2 2 2 1 LisH eIF2A PF08662.11 OQS03996.1 - 1.6e-09 37.9 1.6 0.0071 16.2 0.0 3.9 1 1 2 4 4 4 3 Eukaryotic translation initiation factor eIF2A Coatomer_WDAD PF04053.14 OQS03996.1 - 6.5e-06 25.5 0.3 0.077 12.0 0.0 2.8 3 1 0 3 3 3 2 Coatomer WD associated region WD40_like PF17005.5 OQS03996.1 - 0.00014 21.3 0.1 0.1 11.9 0.0 2.5 2 0 0 2 2 2 2 WD40-like domain IKI3 PF04762.12 OQS03996.1 - 0.00016 19.9 1.3 0.18 9.8 1.0 2.4 2 1 0 2 2 2 2 IKI3 family PD40 PF07676.12 OQS03996.1 - 0.048 13.6 0.6 27 4.9 0.0 3.8 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat DUF1918 PF08940.11 OQS03996.1 - 0.1 12.3 0.1 12 5.7 0.1 3.6 3 0 0 3 3 3 0 Domain of unknown function (DUF1918) Glucan_synthase PF02364.15 OQS03997.1 - 4.2e-187 624.0 19.9 5.4e-169 564.1 9.1 3.0 2 1 1 3 3 3 2 1,3-beta-glucan synthase component FKS1_dom1 PF14288.6 OQS03997.1 - 2.1e-23 83.1 1.4 1.7e-22 80.1 1.4 2.5 1 1 0 1 1 1 1 1,3-beta-glucan synthase subunit FKS1, domain-1 Sugar_tr PF00083.24 OQS03997.1 - 2.8e-18 66.0 28.4 2.8e-18 66.0 28.4 2.3 2 1 0 2 2 2 1 Sugar (and other) transporter TPR_2 PF07719.17 OQS03997.1 - 1.4e-05 24.8 1.2 0.009 16.1 0.0 3.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.6 OQS03997.1 - 0.00042 19.9 0.1 0.16 11.6 0.0 3.6 3 0 0 3 3 3 1 TPR repeat TPR_19 PF14559.6 OQS03997.1 - 0.0015 19.0 2.3 0.077 13.5 0.1 3.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.28 OQS03997.1 - 0.0038 17.0 2.5 0.15 11.9 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 OQS03997.1 - 0.0045 17.1 0.4 0.034 14.4 0.1 2.8 2 0 0 2 2 1 1 Tetratricopeptide repeat DUF4605 PF15378.6 OQS03997.1 - 0.016 15.1 1.4 9.3 6.2 0.0 3.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4605) ANAPC3 PF12895.7 OQS03997.1 - 0.1 12.8 0.3 0.71 10.1 0.0 2.6 3 0 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.6 OQS03997.1 - 0.17 12.3 0.1 1.2 9.6 0.0 2.6 2 0 0 2 2 1 0 Tetratricopeptide repeat CcmE PF03100.15 OQS03997.1 - 3.1 7.8 5.1 0.88 9.6 0.1 2.6 2 0 0 2 2 2 0 CcmE ABC_tran PF00005.27 OQS03998.1 - 9.9e-28 97.4 0.0 1.7e-27 96.6 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 OQS03998.1 - 1e-07 32.1 0.0 0.00089 19.2 0.0 2.3 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 OQS03998.1 - 0.00027 20.5 0.1 0.27 10.6 0.0 2.2 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 OQS03998.1 - 0.0044 17.5 0.0 0.0093 16.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain DUF2612 PF11041.8 OQS03998.1 - 0.0045 16.9 0.0 0.008 16.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2612) AAA_16 PF13191.6 OQS03998.1 - 0.0059 17.0 0.1 0.011 16.2 0.1 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 OQS03998.1 - 0.0066 16.2 0.1 0.014 15.2 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain Mg_chelatase PF01078.21 OQS03998.1 - 0.0081 15.6 0.0 1.7 8.0 0.0 2.2 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI SRP54 PF00448.22 OQS03998.1 - 0.062 12.9 0.1 0.13 11.8 0.1 1.5 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain GATase_7 PF13537.6 OQS03998.1 - 0.11 12.5 0.0 0.23 11.4 0.0 1.5 1 0 0 1 1 1 0 Glutamine amidotransferase domain AAA_25 PF13481.6 OQS03998.1 - 0.13 11.9 0.1 0.3 10.6 0.1 1.6 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 OQS03998.1 - 0.13 12.0 0.0 3.3 7.4 0.0 2.3 2 0 0 2 2 2 0 IstB-like ATP binding protein DUF87 PF01935.17 OQS03998.1 - 0.15 12.1 1.7 1.5 8.9 0.5 2.3 2 0 0 2 2 2 0 Helicase HerA, central domain LCM PF04072.14 OQS03999.1 - 5.3e-30 104.8 0.0 4.9e-29 101.6 0.0 2.0 1 1 0 1 1 1 1 Leucine carboxyl methyltransferase DnaJ PF00226.31 OQS04000.1 - 3.3e-23 81.6 4.1 4.5e-23 81.1 4.1 1.2 1 0 0 1 1 1 1 DnaJ domain ResIII PF04851.15 OQS04001.1 - 0.089 12.8 0.0 0.17 11.9 0.0 1.4 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit NAD_binding_2 PF03446.15 OQS04002.1 - 1.7e-50 171.3 2.6 3.1e-50 170.4 2.6 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 OQS04002.1 - 1.1e-29 103.1 0.0 1.8e-29 102.4 0.0 1.3 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase LRR_4 PF12799.7 OQS04002.1 - 3.2e-14 52.8 18.7 2.5e-08 34.1 1.6 3.8 3 1 1 4 4 4 3 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 OQS04002.1 - 1.9e-09 37.2 1.6 7.2e-05 22.4 0.1 2.2 1 1 1 2 2 2 2 Leucine-rich repeat LRR_8 PF13855.6 OQS04002.1 - 4.7e-08 32.7 10.7 9.3e-05 22.1 0.9 3.9 3 2 0 3 3 3 2 Leucine rich repeat F420_oxidored PF03807.17 OQS04002.1 - 3.7e-06 27.4 0.1 1.8e-05 25.2 0.0 2.1 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.19 OQS04002.1 - 5.4e-06 25.9 0.0 9.9e-06 25.0 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.18 OQS04002.1 - 0.0011 18.9 0.7 0.0063 16.4 0.2 2.1 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.14 OQS04002.1 - 0.0068 16.0 0.6 0.091 12.3 0.4 2.2 1 1 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain TrkA_N PF02254.18 OQS04002.1 - 0.0083 16.4 0.1 0.019 15.2 0.1 1.6 1 0 0 1 1 1 1 TrkA-N domain ApbA PF02558.16 OQS04002.1 - 0.066 12.9 0.1 0.13 11.9 0.1 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA LRR_6 PF13516.6 OQS04002.1 - 0.21 11.7 3.7 53 4.2 0.0 4.1 3 0 0 3 3 3 0 Leucine Rich repeat LRR_1 PF00560.33 OQS04002.1 - 1.3 9.8 8.8 26 5.9 0.4 4.9 5 1 0 5 5 4 0 Leucine Rich Repeat Cellulase PF00150.18 OQS04003.1 - 3.2e-12 46.5 0.6 1.4e-11 44.3 0.6 1.9 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) CAP PF00188.26 OQS04003.1 - 3.3e-10 40.9 2.1 1.4e-09 38.9 2.1 2.2 1 0 0 1 1 1 1 Cysteine-rich secretory protein family Glyco_hydro_cc PF11790.8 OQS04003.1 - 0.00052 19.7 0.0 0.0012 18.5 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core Mt_ATP-synt_B PF05405.14 OQS04004.1 - 0.03 14.0 0.5 0.038 13.6 0.5 1.2 1 1 0 1 1 1 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) Baculo_PEP_C PF04513.12 OQS04005.1 - 0.051 13.6 0.1 0.14 12.2 0.0 1.6 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1515 PF07439.11 OQS04005.1 - 0.15 12.1 0.1 0.25 11.4 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1515) PfkB PF00294.24 OQS04006.1 - 3.7e-29 102.0 0.0 4.5e-29 101.7 0.0 1.1 1 0 0 1 1 1 1 pfkB family carbohydrate kinase DUF2244 PF10003.9 OQS04007.1 - 2 8.1 6.3 27 4.4 4.8 2.4 2 0 0 2 2 2 0 Integral membrane protein (DUF2244) Chromate_transp PF02417.15 OQS04007.1 - 3.7 7.7 12.0 4.4 7.4 10.6 1.8 1 1 0 1 1 1 0 Chromate transporter FGE-sulfatase PF03781.16 OQS04008.1 - 1.4e-20 74.0 0.2 4.7e-20 72.3 0.2 1.8 1 1 0 1 1 1 1 Sulfatase-modifying factor enzyme 1 DinB_2 PF12867.7 OQS04008.1 - 2.7e-05 24.7 0.2 2.7e-05 24.7 0.2 2.2 2 0 0 2 2 2 1 DinB superfamily Rep_trans PF02486.19 OQS04008.1 - 0.07 12.9 0.1 0.17 11.6 0.1 1.6 1 0 0 1 1 1 0 Replication initiation factor FYVE PF01363.21 OQS04010.1 - 1.1e-25 89.5 49.4 2.5e-10 40.3 11.4 3.7 3 0 0 3 3 3 3 FYVE zinc finger START PF01852.19 OQS04010.1 - 6.4e-19 68.2 0.1 6.6e-05 22.4 0.0 3.4 3 0 0 3 3 3 3 START domain LRR_8 PF13855.6 OQS04010.1 - 4.7e-12 45.5 25.4 0.00032 20.4 2.1 6.8 5 1 2 7 7 7 4 Leucine rich repeat FYVE_2 PF02318.16 OQS04010.1 - 4.1e-10 39.9 37.4 0.0017 18.6 6.4 3.6 3 0 0 3 3 3 3 FYVE-type zinc finger LRR_4 PF12799.7 OQS04010.1 - 2.1e-07 31.2 30.5 0.07 13.6 0.0 6.2 1 1 6 7 7 7 6 Leucine Rich repeats (2 copies) IBR PF01485.21 OQS04010.1 - 0.00071 19.7 28.5 0.042 14.1 3.2 4.2 3 0 0 3 3 3 3 IBR domain, a half RING-finger domain LRR_6 PF13516.6 OQS04010.1 - 0.035 14.2 10.9 5.6 7.3 0.2 5.6 4 0 0 4 4 4 0 Leucine Rich repeat Ion_trans PF00520.31 OQS04011.1 - 7.1e-05 22.2 32.0 7.1e-05 22.2 32.0 2.6 1 1 1 2 2 2 1 Ion transport protein Troponin PF00992.20 OQS04011.1 - 0.031 14.6 0.2 0.031 14.6 0.2 2.3 3 0 0 3 3 3 0 Troponin RIC3 PF15361.6 OQS04011.1 - 0.16 12.4 0.4 0.33 11.3 0.4 1.7 1 0 0 1 1 1 0 Resistance to inhibitors of cholinesterase homologue 3 LRR_8 PF13855.6 OQS04012.1 - 4.1e-25 87.3 30.0 5.6e-08 32.4 0.3 7.1 4 3 3 7 7 7 6 Leucine rich repeat LRR_4 PF12799.7 OQS04012.1 - 3.6e-18 65.3 28.3 0.00065 20.0 1.7 8.0 6 2 1 7 7 7 6 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 OQS04012.1 - 0.014 14.9 13.6 0.55 9.7 0.2 4.3 1 1 3 5 5 5 0 Leucine-rich repeat LRR_6 PF13516.6 OQS04012.1 - 4.7 7.5 8.5 1.6e+02 2.8 0.3 5.8 6 0 0 6 6 6 0 Leucine Rich repeat 7tm_2 PF00002.24 OQS04013.1 - 4.4e-18 65.5 14.6 2.4e-17 63.0 14.6 1.9 1 1 0 1 1 1 1 7 transmembrane receptor (Secretin family) Dicty_CAR PF05462.11 OQS04013.1 - 3e-14 52.9 10.2 3.7e-14 52.6 10.2 1.2 1 0 0 1 1 1 1 Slime mold cyclic AMP receptor Git3 PF11710.8 OQS04013.1 - 0.01 15.6 5.9 0.015 15.1 4.5 2.0 1 1 1 2 2 2 0 G protein-coupled glucose receptor regulating Gpa2 GPR_Gpa2_C PF11970.8 OQS04013.1 - 0.49 10.5 4.9 2.7 8.1 0.1 3.2 2 1 1 3 3 3 0 G protein-coupled glucose receptor regulating Gpa2 C-term EamA PF00892.20 OQS04014.1 - 6.3e-12 45.8 27.8 1.2e-07 32.0 14.6 2.2 2 0 0 2 2 2 2 EamA-like transporter family CrgA PF06781.12 OQS04015.1 - 0.092 12.8 0.0 0.22 11.6 0.0 1.6 1 0 0 1 1 1 0 Cell division protein CrgA DnaJ PF00226.31 OQS04016.1 - 7.7e-08 32.4 2.6 1.5e-07 31.4 2.6 1.5 1 0 0 1 1 1 1 DnaJ domain PFU PF09070.11 OQS04016.1 - 0.0023 18.2 0.9 15 5.9 0.0 5.5 7 0 0 7 7 7 1 PFU (PLAA family ubiquitin binding) dsRBD2 PF17842.1 OQS04016.1 - 0.022 14.9 0.2 1.7 8.8 0.0 2.4 2 0 0 2 2 2 0 Double-stranded RNA binding domain 2 Myb_DNA-binding PF00249.31 OQS04018.1 - 4e-09 36.5 0.3 6.1e-09 35.9 0.3 1.3 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OQS04018.1 - 0.099 12.9 0.4 0.16 12.3 0.4 1.3 1 0 0 1 1 1 0 Myb-like DNA-binding domain Adaptin_binding PF10199.9 OQS04019.1 - 7e-12 46.0 5.8 1.1e-10 42.2 5.8 2.1 1 1 0 1 1 1 1 Alpha and gamma adaptin binding protein p34 Diphthami_syn_2 PF01902.17 OQS04021.1 - 1.7e-36 125.8 0.0 2e-36 125.6 0.0 1.0 1 0 0 1 1 1 1 Diphthamide synthase Rab5ip PF07019.12 OQS04022.1 - 2.8e-15 56.7 6.8 3.3e-15 56.4 6.8 1.1 1 0 0 1 1 1 1 Rab5-interacting protein (Rab5ip) VID27_PH PF17747.1 OQS04022.1 - 0.092 13.0 0.0 0.098 12.9 0.0 1.2 1 0 0 1 1 1 0 VID27 PH-like domain Phage_holin_3_6 PF07332.11 OQS04022.1 - 1.2 9.2 11.0 10 6.2 11.0 1.9 1 1 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III Prefoldin PF02996.17 OQS04023.1 - 1.1e-25 89.8 0.1 1.8e-25 89.2 0.1 1.3 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin_2 PF01920.20 OQS04023.1 - 0.015 15.2 4.4 0.12 12.3 0.9 2.4 1 1 1 2 2 2 0 Prefoldin subunit Cast PF10174.9 OQS04023.1 - 1.1 7.5 6.4 1.3 7.2 0.3 2.7 3 0 0 3 3 3 0 RIM-binding protein of the cytomatrix active zone Metallophos PF00149.28 OQS04024.1 - 2.1e-13 51.3 0.1 3e-13 50.8 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 OQS04024.1 - 0.0016 18.7 0.0 0.0056 16.9 0.0 1.8 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Peptidase_U57 PF05582.12 OQS04024.1 - 0.058 12.6 0.0 0.093 12.0 0.0 1.2 1 0 0 1 1 1 0 YabG peptidase U57 Myb_DNA-binding PF00249.31 OQS04025.1 - 1.2e-09 38.2 0.1 2e-09 37.5 0.1 1.3 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OQS04025.1 - 0.0068 16.6 0.2 0.0091 16.2 0.2 1.3 1 0 0 1 1 1 1 Myb-like DNA-binding domain Vps26 PF03643.15 OQS04028.1 - 9.3e-35 120.0 0.1 1.2e-34 119.6 0.1 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Gly_radical PF01228.21 OQS04028.1 - 0.087 13.4 0.0 0.18 12.3 0.0 1.5 1 0 0 1 1 1 0 Glycine radical Cpn60_TCP1 PF00118.24 OQS04029.1 - 4.1e-153 510.5 14.9 5.5e-153 510.1 14.9 1.2 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family PIP5K PF01504.18 OQS04029.1 - 9.9e-70 234.9 0.0 1.9e-69 234.0 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase SCAB_CC PF16712.5 OQS04029.1 - 0.22 11.3 2.3 0.2 11.5 0.1 1.9 2 0 0 2 2 2 0 Coiled-coil regions of plant-specific actin-binding protein DUF2207 PF09972.9 OQS04029.1 - 5.3 5.7 8.2 3.4e+02 -0.3 8.2 2.4 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) HTH_psq PF05225.16 OQS04030.1 - 1.7e-10 40.4 0.0 2.5e-06 27.1 0.0 2.7 2 0 0 2 2 2 2 helix-turn-helix, Psq domain HTH_23 PF13384.6 OQS04030.1 - 0.0086 15.8 0.3 0.028 14.2 0.0 2.0 2 0 0 2 2 2 1 Homeodomain-like domain HTH_29 PF13551.6 OQS04030.1 - 0.074 13.1 0.0 0.35 10.9 0.0 2.0 2 0 0 2 2 2 0 Winged helix-turn helix HTH_1 PF00126.27 OQS04030.1 - 1.8 8.5 0.0 1.8 8.5 0.0 2.9 3 0 0 3 3 3 0 Bacterial regulatory helix-turn-helix protein, lysR family SLC12 PF03522.15 OQS04030.1 - 5.8 5.8 18.5 8.2 5.3 18.5 1.2 1 0 0 1 1 1 0 Solute carrier family 12 HA2 PF04408.23 OQS04031.1 - 5.3e-20 71.7 2.7 9.5e-16 58.0 0.0 3.6 3 0 0 3 3 3 2 Helicase associated domain (HA2) Helicase_C PF00271.31 OQS04031.1 - 5.3e-14 52.5 0.2 1.6e-13 51.0 0.2 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 OQS04031.1 - 2.1e-12 47.1 0.2 4.9e-12 46.0 0.2 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase OB_NTP_bind PF07717.16 OQS04031.1 - 2.4e-12 47.0 0.0 6.4e-12 45.7 0.0 1.8 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DND1_DSRM PF14709.7 OQS04031.1 - 2.3e-07 31.0 0.3 6.5e-07 29.5 0.0 2.0 2 0 0 2 2 2 1 double strand RNA binding domain from DEAD END PROTEIN 1 AAA_22 PF13401.6 OQS04031.1 - 1.8e-05 25.0 0.2 5.7e-05 23.4 0.2 1.8 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 OQS04031.1 - 2e-05 24.9 0.0 4.8e-05 23.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain Alpha-mann_mid PF09261.11 OQS04031.1 - 0.00056 20.0 0.1 2.1 8.5 0.0 3.0 2 0 0 2 2 2 2 Alpha mannosidase middle domain ATPase PF06745.13 OQS04031.1 - 0.0021 17.4 0.0 0.0065 15.8 0.0 1.8 1 0 0 1 1 1 1 KaiC AAA_23 PF13476.6 OQS04031.1 - 0.0047 17.5 2.3 0.19 12.2 0.0 2.8 2 0 0 2 2 2 1 AAA domain T2SSE PF00437.20 OQS04031.1 - 0.0089 15.1 0.0 0.024 13.7 0.0 1.8 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_30 PF13604.6 OQS04031.1 - 0.015 15.0 0.0 0.032 14.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 OQS04031.1 - 0.039 14.3 0.0 0.14 12.5 0.0 2.0 1 0 0 1 1 1 0 AAA ATPase domain PhoH PF02562.16 OQS04031.1 - 0.075 12.5 0.0 0.16 11.4 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein Rad17 PF03215.15 OQS04031.1 - 0.077 12.9 0.0 0.19 11.6 0.0 1.6 1 0 0 1 1 1 0 Rad17 P-loop domain ABC_tran PF00005.27 OQS04031.1 - 0.098 13.2 0.1 0.6 10.6 0.0 2.4 2 0 0 2 2 1 0 ABC transporter dsRBD2 PF17842.1 OQS04031.1 - 0.13 12.4 3.5 0.15 12.3 0.1 2.4 2 0 0 2 2 2 0 Double-stranded RNA binding domain 2 AAA_29 PF13555.6 OQS04031.1 - 0.13 12.0 0.0 0.34 10.7 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_11 PF13086.6 OQS04031.1 - 0.71 9.6 5.9 4.4 7.0 0.0 2.7 2 1 0 2 2 2 0 AAA domain UBX PF00789.20 OQS04032.1 - 1.2e-14 54.3 0.0 2.3e-14 53.3 0.0 1.5 1 0 0 1 1 1 1 UBX domain Thioredoxin_7 PF13899.6 OQS04032.1 - 1.2e-11 44.6 0.1 5.2e-11 42.6 0.0 2.0 2 0 0 2 2 2 1 Thioredoxin-like UBA_4 PF14555.6 OQS04032.1 - 5.1e-11 42.2 0.1 1.1e-10 41.2 0.1 1.6 1 0 0 1 1 1 1 UBA-like domain TAP_C PF03943.13 OQS04032.1 - 0.0024 17.5 1.2 0.0044 16.6 0.0 2.0 2 0 0 2 2 2 1 TAP C-terminal domain UIM PF02809.20 OQS04032.1 - 0.0083 16.0 4.7 0.02 14.8 4.7 1.7 1 0 0 1 1 1 1 Ubiquitin interaction motif DUF4611 PF15387.6 OQS04032.1 - 0.19 12.0 1.0 2.8 8.2 0.4 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) LRR_4 PF12799.7 OQS04033.1 - 1.3e-18 66.7 18.2 3.3e-06 27.3 0.0 5.8 4 2 2 6 6 6 5 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 OQS04033.1 - 1.9e-10 40.5 7.2 5.5e-09 35.8 2.1 3.1 1 1 0 2 2 2 2 Leucine-rich repeat LRR_8 PF13855.6 OQS04033.1 - 3.3e-10 39.6 16.3 3.4e-05 23.5 0.8 5.2 1 1 4 5 5 5 4 Leucine rich repeat LRR_6 PF13516.6 OQS04033.1 - 1.1e-09 37.5 11.3 0.11 12.6 0.0 6.7 6 0 0 6 6 6 3 Leucine Rich repeat LRR_1 PF00560.33 OQS04033.1 - 9.2e-06 25.5 10.3 12 6.9 0.0 7.0 7 0 0 7 7 7 1 Leucine Rich Repeat BAG PF02179.16 OQS04033.1 - 0.082 13.3 3.5 0.12 12.9 1.0 2.5 2 1 0 2 2 2 0 BAG domain polyprenyl_synt PF00348.17 OQS04034.1 - 1.7e-91 305.8 0.0 3.7e-90 301.5 0.0 2.6 2 0 0 2 2 2 1 Polyprenyl synthetase SCAPER_N PF16501.5 OQS04034.1 - 1.2e-17 63.7 1.1 1.2e-17 63.7 1.1 2.6 3 0 0 3 3 3 1 S phase cyclin A-associated protein in the endoplasmic reticulum Glyco_transf_41 PF13844.6 OQS04034.1 - 0.5 8.8 5.7 0.06 11.8 0.1 2.0 2 0 0 2 2 2 0 Glycosyl transferase family 41 Snapin_Pallidin PF14712.6 OQS04035.1 - 1e-08 35.4 0.0 1.4e-08 35.1 0.0 1.2 1 0 0 1 1 1 1 Snapin/Pallidin MORN PF02493.20 OQS04036.1 - 4.4e-38 126.9 42.3 8.2e-07 28.6 0.5 10.9 11 0 0 11 11 11 8 MORN repeat Kelch_3 PF13415.6 OQS04036.1 - 2.1e-19 69.3 0.7 0.0094 16.2 0.0 7.0 6 1 0 6 6 6 4 Galactose oxidase, central domain Kelch_4 PF13418.6 OQS04036.1 - 8.7e-16 57.7 3.2 0.08 13.0 0.0 6.8 7 0 0 7 7 7 4 Galactose oxidase, central domain Kelch_5 PF13854.6 OQS04036.1 - 1.7e-14 53.4 3.2 0.38 10.8 0.0 7.0 7 1 0 7 7 7 5 Kelch motif Kelch_6 PF13964.6 OQS04036.1 - 1.3e-13 50.6 0.5 0.094 13.0 0.0 6.6 6 0 0 6 6 6 4 Kelch motif Kelch_1 PF01344.25 OQS04036.1 - 3.5e-07 29.7 5.4 2.2 7.9 0.1 6.5 6 0 0 6 6 6 3 Kelch motif DUF3048_C PF17479.2 OQS04036.1 - 6.2 7.2 11.9 40 4.6 0.1 4.7 3 2 2 5 5 5 0 Protein of unknown function (DUF3048) C-terminal domain RPAP2_Rtr1 PF04181.13 OQS04037.1 - 1.7e-16 60.3 1.1 4.4e-16 59.0 0.8 1.9 2 0 0 2 2 2 1 Rtr1/RPAP2 family SAWADEE PF16719.5 OQS04037.1 - 0.013 15.5 0.2 0.031 14.3 0.2 1.6 1 0 0 1 1 1 0 SAWADEE domain NOG1_N PF17835.1 OQS04037.1 - 0.064 13.2 0.6 0.12 12.3 0.0 1.7 2 0 0 2 2 2 0 NOG1 N-terminal helical domain DTW PF03942.15 OQS04037.1 - 0.19 11.4 2.5 2.5 7.8 1.0 2.3 2 0 0 2 2 2 0 DTW domain Ank_5 PF13857.6 OQS04038.1 - 7.9e-09 35.6 0.0 0.00028 21.1 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeats (many copies) PDZ PF00595.24 OQS04038.1 - 4.2e-06 27.0 0.0 1.1e-05 25.7 0.0 1.7 1 0 0 1 1 1 1 PDZ domain Ank_4 PF13637.6 OQS04038.1 - 0.00037 21.0 0.0 0.0011 19.4 0.0 1.8 1 1 0 1 1 1 1 Ankyrin repeats (many copies) PDZ_6 PF17820.1 OQS04038.1 - 0.0027 17.5 0.0 0.0058 16.5 0.0 1.6 1 0 0 1 1 1 1 PDZ domain Ank_2 PF12796.7 OQS04038.1 - 0.0031 18.1 0.0 0.0066 17.0 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 OQS04038.1 - 0.063 13.8 0.3 21 5.8 0.0 2.7 2 0 0 2 2 2 0 Ankyrin repeat GTP_EFTU PF00009.27 OQS04040.1 - 8.1e-53 178.9 0.0 1.2e-51 175.0 0.0 2.2 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 OQS04040.1 - 1.4e-42 144.6 0.1 2.7e-42 143.6 0.1 1.5 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain ABC_tran PF00005.27 OQS04040.1 - 7.9e-24 84.7 0.1 3.7e-23 82.6 0.0 2.1 2 0 0 2 2 2 1 ABC transporter ABC2_membrane PF01061.24 OQS04040.1 - 1.1e-16 60.9 10.9 1.1e-16 60.9 10.9 2.0 1 1 0 2 2 2 1 ABC-2 type transporter GTP_EFTU_D2 PF03144.25 OQS04040.1 - 7.9e-15 55.0 0.2 6.3e-14 52.1 0.2 2.4 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 OQS04040.1 - 4.9e-08 33.0 0.1 0.021 14.9 0.0 3.7 3 0 0 3 3 3 2 50S ribosome-binding GTPase AAA_21 PF13304.6 OQS04040.1 - 2e-06 27.9 3.7 0.012 15.5 0.3 2.3 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 OQS04040.1 - 0.00018 21.2 0.3 0.019 14.7 0.2 3.4 3 0 0 3 3 3 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 OQS04040.1 - 0.00059 19.8 0.5 0.0072 16.2 0.0 2.9 3 0 0 3 3 3 1 RsgA GTPase SMC_N PF02463.19 OQS04040.1 - 0.00068 19.1 0.0 0.21 11.0 0.0 2.4 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 OQS04040.1 - 0.0018 18.5 0.1 0.32 11.3 0.0 2.8 3 0 0 3 3 3 1 AAA domain AAA_23 PF13476.6 OQS04040.1 - 0.012 16.2 0.8 0.02 15.4 0.1 1.7 2 0 0 2 2 1 0 AAA domain AAA_16 PF13191.6 OQS04040.1 - 0.019 15.3 0.0 0.043 14.2 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain FlpD PF02662.16 OQS04040.1 - 0.03 14.3 0.0 0.1 12.6 0.0 1.9 2 0 0 2 2 2 0 Methyl-viologen-reducing hydrogenase, delta subunit ATPase_2 PF01637.18 OQS04040.1 - 0.046 13.6 0.3 0.22 11.4 0.0 2.2 3 0 0 3 3 3 0 ATPase domain predominantly from Archaea NACHT PF05729.12 OQS04040.1 - 0.055 13.4 0.1 0.19 11.7 0.1 1.9 2 0 0 2 2 2 0 NACHT domain AAA_18 PF13238.6 OQS04040.1 - 0.12 12.9 0.0 1.4 9.5 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 OQS04040.1 - 0.13 11.9 0.0 0.36 10.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain Dynamin_N PF00350.23 OQS04040.1 - 0.22 11.5 0.7 11 6.0 0.3 2.9 3 0 0 3 3 3 0 Dynamin family AAA_28 PF13521.6 OQS04040.1 - 0.4 10.9 1.2 0.49 10.6 0.1 1.7 2 0 0 2 2 1 0 AAA domain Pkinase PF00069.25 OQS04041.1 - 2.4e-71 240.2 0.0 3.1e-71 239.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQS04041.1 - 4.3e-35 121.2 0.0 6.2e-35 120.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 OQS04041.1 - 0.00017 20.7 0.0 0.00027 20.0 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 OQS04041.1 - 0.0004 19.8 0.0 0.00077 18.9 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 OQS04041.1 - 0.011 15.2 0.0 0.019 14.3 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family POPLD PF08170.12 OQS04041.1 - 0.047 14.0 0.8 0.14 12.5 0.8 1.8 1 0 0 1 1 1 0 POPLD (NUC188) domain Ku PF02735.16 OQS04042.1 - 4.3e-40 137.6 0.2 5.7e-39 133.9 0.0 2.3 2 0 0 2 2 2 1 Ku70/Ku80 beta-barrel domain Ku_N PF03731.15 OQS04042.1 - 6.1e-16 58.8 1.2 1.3e-15 57.7 1.2 1.6 1 0 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain Ku_PK_bind PF08785.11 OQS04042.1 - 2.4e-11 43.8 2.7 1.4e-10 41.4 0.1 3.1 2 1 0 2 2 2 1 Ku C terminal domain like VWA_2 PF13519.6 OQS04042.1 - 7.9e-10 39.3 0.3 1.6e-08 35.2 0.3 3.1 2 1 0 2 2 2 1 von Willebrand factor type A domain VWA PF00092.28 OQS04042.1 - 4.2e-05 23.9 2.5 0.00011 22.6 2.5 1.7 1 1 0 1 1 1 1 von Willebrand factor type A domain Ku_C PF03730.14 OQS04042.1 - 0.00014 22.5 2.8 0.00019 22.1 0.5 2.5 2 0 0 2 2 2 1 Ku70/Ku80 C-terminal arm WD40 PF00400.32 OQS04043.1 - 7.4e-15 55.1 3.2 1.7e-06 28.7 0.2 4.7 4 0 0 4 4 4 3 WD domain, G-beta repeat DUF5018 PF16410.5 OQS04043.1 - 0.01 14.6 0.0 0.12 11.0 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF5018) Peptidase_C62 PF12380.8 OQS04043.1 - 0.051 12.7 0.0 0.097 11.8 0.0 1.5 1 0 0 1 1 1 0 Gill-associated viral 3C-like peptidase Cgr1 PF03879.14 OQS04044.1 - 1.8e-11 44.4 28.7 2.2e-11 44.1 28.7 1.1 1 0 0 1 1 1 1 Cgr1 family Membralin PF09746.9 OQS04044.1 - 4.4 6.3 8.7 5.3 6.0 8.7 1.0 1 0 0 1 1 1 0 Tumour-associated protein DDHD PF02862.17 OQS04044.1 - 8.1 6.5 9.0 9.9 6.3 9.0 1.1 1 0 0 1 1 1 0 DDHD domain ABC_tran PF00005.27 OQS04045.1 - 5e-28 98.3 0.0 9.9e-28 97.4 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 OQS04045.1 - 4.4e-11 43.1 0.1 9.7e-08 32.2 0.0 2.3 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 OQS04045.1 - 0.00054 19.8 0.0 0.018 14.7 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain SLATT_1 PF18181.1 OQS04045.1 - 0.019 14.9 0.0 0.044 13.7 0.0 1.5 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain 1 ATP_bind_3 PF01171.20 OQS04045.1 - 0.047 13.4 0.0 17 5.1 0.0 3.1 2 1 1 3 3 3 0 PP-loop family SbcCD_C PF13558.6 OQS04045.1 - 0.087 13.1 0.0 1.2 9.4 0.0 2.5 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit Thymidylate_kin PF02223.17 OQS04045.1 - 0.18 11.4 0.5 0.75 9.5 0.0 2.2 4 0 0 4 4 4 0 Thymidylate kinase Sulfotransfer_3 PF13469.6 OQS04046.1 - 6.8e-30 105.1 0.1 2.5e-29 103.2 0.1 1.8 1 1 0 1 1 1 1 Sulfotransferase family Sulfotransfer_1 PF00685.27 OQS04046.1 - 1.7e-09 37.6 0.2 3.1e-09 36.7 0.2 1.4 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_4 PF17784.1 OQS04046.1 - 0.089 12.6 4.3 0.63 9.8 4.2 2.2 1 1 0 1 1 1 0 Sulfotransferase domain TauE PF01925.19 OQS04047.1 - 1.7e-22 80.2 20.5 3.2e-12 46.6 1.7 2.1 2 0 0 2 2 2 2 Sulfite exporter TauE/SafE DPCD PF14913.6 OQS04047.1 - 0.027 13.8 1.2 0.042 13.2 1.2 1.2 1 0 0 1 1 1 0 DPCD protein family PIG-P PF08510.12 OQS04047.1 - 1.5 8.8 0.0 1.5 8.8 0.0 2.8 3 1 0 3 3 3 0 PIG-P Ribosomal_L23 PF00276.20 OQS04048.1 - 1.9e-14 53.8 0.4 5.2e-14 52.4 0.4 1.7 1 0 0 1 1 1 1 Ribosomal protein L23 Ribosomal_L23eN PF03939.13 OQS04048.1 - 4.6e-11 42.8 7.1 1.3e-10 41.3 7.1 1.8 1 0 0 1 1 1 1 Ribosomal protein L23, N-terminal domain YihI PF04220.12 OQS04048.1 - 0.039 13.7 0.1 0.039 13.7 0.1 1.6 2 0 0 2 2 2 0 Der GTPase activator (YihI) HisKA_7TM PF16927.5 OQS04048.1 - 0.2 11.6 7.2 0.26 11.3 2.6 2.3 2 0 0 2 2 2 0 N-terminal 7TM region of histidine kinase Alba PF01918.21 OQS04048.1 - 0.4 10.5 2.3 4.6 7.2 0.8 2.7 2 0 0 2 2 2 0 Alba DXP_reductoisom PF02670.16 OQS04048.1 - 0.41 11.4 3.3 0.28 11.9 1.1 1.9 2 0 0 2 2 2 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase BT1 PF03092.16 OQS04049.1 - 3.7e-12 45.3 21.4 5e-11 41.5 2.1 3.8 4 0 0 4 4 4 3 BT1 family PUCC PF03209.15 OQS04049.1 - 0.00018 20.7 1.1 0.00055 19.1 1.1 1.9 1 1 0 1 1 1 1 PUCC protein DUF1541 PF07563.11 OQS04049.1 - 0.19 11.6 0.1 0.42 10.5 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1541) Shugoshin_N PF07558.11 OQS04050.1 - 0.0037 17.1 1.0 3 7.8 0.0 2.8 2 0 0 2 2 2 2 Shugoshin N-terminal coiled-coil region T3SSipB PF16535.5 OQS04050.1 - 0.4 11.1 17.2 0.56 10.7 10.1 2.7 1 1 1 2 2 2 0 Type III cell invasion protein SipB DUF1319 PF07028.11 OQS04050.1 - 3.1 8.1 11.0 7 6.9 0.2 3.4 3 1 0 3 3 3 0 Protein of unknown function (DUF1319) HEAT PF02985.22 OQS04051.1 - 1.9e-31 105.4 22.2 0.00096 19.2 0.0 13.0 13 0 0 13 13 13 8 HEAT repeat HEAT_2 PF13646.6 OQS04051.1 - 4.2e-22 78.4 6.8 0.00022 21.5 0.5 7.9 2 2 4 7 7 7 6 HEAT repeats Vac14_Fab1_bd PF12755.7 OQS04051.1 - 9.4e-12 45.4 0.2 0.73 10.5 0.0 6.0 1 1 5 6 6 6 4 Vacuolar 14 Fab1-binding region Cnd1 PF12717.7 OQS04051.1 - 1.3e-09 38.4 3.3 0.036 14.1 0.2 5.1 2 1 4 6 6 6 3 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 OQS04051.1 - 2.8e-09 37.3 5.7 0.061 13.8 0.0 7.6 9 0 0 9 9 9 2 HEAT-like repeat Adaptin_N PF01602.20 OQS04051.1 - 5.6e-06 25.2 2.4 0.018 13.6 0.8 3.9 1 1 0 2 2 2 2 Adaptin N terminal region IFRD PF05004.13 OQS04051.1 - 0.0092 15.1 2.0 0.32 10.1 0.2 2.8 2 1 0 2 2 2 1 Interferon-related developmental regulator (IFRD) Tti2 PF10521.9 OQS04051.1 - 0.011 15.3 0.1 0.024 14.2 0.1 1.5 1 0 0 1 1 1 0 Tti2 family TetR_C_18 PF17923.1 OQS04051.1 - 0.099 13.2 0.6 3.7 8.1 0.2 2.8 1 1 1 2 2 2 0 Tetracyclin repressor-like, C-terminal domain LRV PF01816.17 OQS04051.1 - 6.3 7.4 8.4 84 3.9 0.0 5.1 4 0 0 4 4 4 0 Leucine rich repeat variant Pkinase PF00069.25 OQS04052.1 - 2.1e-17 63.4 0.0 1.4e-10 41.0 0.0 2.4 2 0 0 2 2 2 2 Protein kinase domain WD40 PF00400.32 OQS04052.1 - 1e-15 57.8 9.4 0.00019 22.2 0.0 5.9 5 0 0 5 5 5 4 WD domain, G-beta repeat HEAT PF02985.22 OQS04052.1 - 4.2e-09 35.9 12.1 0.11 12.8 0.1 6.4 6 0 0 6 6 6 3 HEAT repeat Adaptin_N PF01602.20 OQS04052.1 - 9.1e-06 24.5 0.7 3e-05 22.8 0.1 1.9 1 1 1 2 2 2 1 Adaptin N terminal region HEAT_2 PF13646.6 OQS04052.1 - 2.6e-05 24.5 1.1 0.021 15.2 0.1 4.2 3 2 2 5 5 5 1 HEAT repeats Pkinase_Tyr PF07714.17 OQS04052.1 - 7.3e-05 22.2 0.0 0.0057 16.0 0.0 2.3 2 0 0 2 2 2 1 Protein tyrosine kinase ANAPC4_WD40 PF12894.7 OQS04052.1 - 0.00036 20.8 0.3 0.45 10.9 0.0 3.3 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Tti2 PF10521.9 OQS04052.1 - 0.0016 18.0 0.1 0.0037 16.9 0.1 1.6 1 0 0 1 1 1 1 Tti2 family Ge1_WD40 PF16529.5 OQS04052.1 - 0.013 14.5 0.0 0.18 10.8 0.0 2.4 2 0 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Tfb5 PF06331.12 OQS04052.1 - 0.1 12.6 0.1 0.46 10.5 0.0 2.0 2 0 0 2 2 2 0 Transcription factor TFIIH complex subunit Tfb5 DUF5436 PF17504.2 OQS04052.1 - 0.12 12.7 0.1 0.31 11.4 0.1 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5436) BT1 PF03092.16 OQS04053.1 - 3.5e-12 45.3 20.4 1.2e-11 43.6 0.6 3.7 4 1 1 5 5 5 3 BT1 family PUCC PF03209.15 OQS04053.1 - 4.7e-06 25.9 1.2 7.7e-06 25.2 0.0 2.0 2 0 0 2 2 2 1 PUCC protein Pkinase PF00069.25 OQS04054.1 - 3.1e-69 233.3 0.0 6.2e-69 232.3 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain UPRTase PF14681.6 OQS04054.1 - 2.6e-67 226.3 0.1 5.4e-67 225.2 0.1 1.6 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pkinase_Tyr PF07714.17 OQS04054.1 - 3.8e-37 128.0 0.0 7.7e-37 127.0 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OQS04054.1 - 1.9e-07 30.7 0.0 3.9e-07 29.7 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 OQS04054.1 - 1.6e-05 24.3 0.1 3.3e-05 23.3 0.1 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 OQS04054.1 - 7e-05 21.8 0.4 0.00091 18.1 0.0 2.4 3 0 0 3 3 3 1 Fungal protein kinase Trp_repressor PF01371.19 OQS04054.1 - 0.00047 20.2 0.0 0.003 17.6 0.0 2.4 1 1 0 1 1 1 1 Trp repressor protein FTA2 PF13095.6 OQS04054.1 - 0.0023 17.6 0.0 0.091 12.4 0.0 2.5 2 0 0 2 2 2 1 Kinetochore Sim4 complex subunit FTA2 Pribosyltran PF00156.27 OQS04054.1 - 0.0072 15.9 0.1 0.019 14.5 0.0 1.7 2 0 0 2 2 2 1 Phosphoribosyl transferase domain APH PF01636.23 OQS04054.1 - 0.012 15.6 2.9 0.06 13.3 0.0 2.9 3 1 1 4 4 4 0 Phosphotransferase enzyme family UxaE PF16257.5 OQS04054.1 - 0.016 13.9 0.0 0.025 13.3 0.0 1.2 1 0 0 1 1 1 0 tagaturonate epimerase CM_1 PF07736.11 OQS04054.1 - 0.044 14.2 0.2 6 7.3 0.0 2.8 2 0 0 2 2 2 0 Chorismate mutase type I RIO1 PF01163.22 OQS04054.1 - 0.11 12.0 1.2 0.22 11.1 0.2 1.9 2 0 0 2 2 2 0 RIO1 family TetR_C_11 PF16859.5 OQS04054.1 - 0.18 12.1 1.7 0.69 10.2 0.3 2.6 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain Ank PF00023.30 OQS04055.1 - 1.8e-13 50.3 1.6 3.2e-06 27.3 0.2 3.0 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.6 OQS04055.1 - 3.8e-13 49.6 0.5 1.4e-12 47.8 0.5 2.0 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 OQS04055.1 - 1.3e-11 44.9 0.1 4.1e-11 43.3 0.1 1.9 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OQS04055.1 - 7.8e-10 38.8 1.8 3.9e-07 30.2 0.1 2.8 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQS04055.1 - 1.5e-08 34.2 1.6 0.0021 18.4 0.1 3.6 3 0 0 3 3 3 2 Ankyrin repeat WXG100 PF06013.12 OQS04055.1 - 0.0065 16.7 3.0 0.0065 16.7 3.0 2.2 2 0 0 2 2 2 1 Proteins of 100 residues with WXG PI_PP_I PF18363.1 OQS04055.1 - 0.99 9.6 4.8 5.3 7.3 0.5 2.7 1 1 1 2 2 2 0 Phosphoinositide phosphatase insertion domain AAA_2 PF07724.14 OQS04056.1 - 1.3e-32 113.3 0.3 2.4e-25 89.6 0.0 2.6 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA PF00004.29 OQS04056.1 - 1.5e-13 51.3 1.1 2.4e-05 24.8 0.0 3.3 2 1 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 OQS04056.1 - 1.9e-07 31.2 0.1 3.2e-05 24.0 0.0 2.7 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 OQS04056.1 - 6.9e-06 26.4 1.3 0.0047 17.2 1.3 3.4 1 1 0 1 1 1 1 AAA domain MCM PF00493.23 OQS04056.1 - 3.2e-05 23.1 0.1 0.0027 16.9 0.0 2.5 2 0 0 2 2 2 1 MCM P-loop domain Mg_chelatase PF01078.21 OQS04056.1 - 4e-05 23.1 0.2 0.0031 16.9 0.0 3.2 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.26 OQS04056.1 - 0.00011 22.0 0.0 0.022 14.5 0.0 2.7 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_18 PF13238.6 OQS04056.1 - 0.00014 22.4 0.1 0.00071 20.1 0.0 2.3 1 1 2 3 3 3 1 AAA domain AAA_16 PF13191.6 OQS04056.1 - 0.00023 21.6 0.7 0.0011 19.4 0.4 2.2 2 1 0 2 2 1 1 AAA ATPase domain AAA_28 PF13521.6 OQS04056.1 - 0.00028 21.2 0.0 0.00067 19.9 0.0 1.7 2 0 0 2 2 1 1 AAA domain ClpB_D2-small PF10431.9 OQS04056.1 - 0.00031 20.7 0.1 0.0013 18.8 0.0 2.2 1 1 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein T2SSE PF00437.20 OQS04056.1 - 0.00051 19.2 0.1 0.0016 17.6 0.0 1.8 1 1 0 1 1 1 1 Type II/IV secretion system protein Zeta_toxin PF06414.12 OQS04056.1 - 0.00057 19.2 0.0 0.0011 18.3 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin RuvB_N PF05496.12 OQS04056.1 - 0.00063 19.5 0.0 0.86 9.3 0.0 2.8 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain TIP49 PF06068.13 OQS04056.1 - 0.00083 18.7 0.0 0.0018 17.6 0.0 1.5 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_33 PF13671.6 OQS04056.1 - 0.002 18.3 0.4 0.0081 16.3 0.2 2.1 2 1 0 2 2 2 1 AAA domain Cytidylate_kin PF02224.18 OQS04056.1 - 0.0027 17.5 0.3 1.3 8.7 0.0 2.7 2 1 0 2 2 2 1 Cytidylate kinase CPT PF07931.12 OQS04056.1 - 0.0032 17.3 0.0 0.0077 16.1 0.0 1.6 1 0 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein G-alpha PF00503.20 OQS04056.1 - 0.0052 16.0 0.0 0.0076 15.4 0.0 1.3 1 0 0 1 1 1 1 G-protein alpha subunit TsaE PF02367.17 OQS04056.1 - 0.012 15.6 0.0 0.028 14.4 0.0 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE DEAD PF00270.29 OQS04056.1 - 0.021 14.6 0.0 0.25 11.1 0.0 2.4 2 0 0 2 2 2 0 DEAD/DEAH box helicase DUF87 PF01935.17 OQS04056.1 - 0.028 14.5 0.8 5.1 7.1 0.1 3.3 2 1 1 3 3 3 0 Helicase HerA, central domain NTPase_1 PF03266.15 OQS04056.1 - 0.055 13.4 0.1 1.4 8.9 0.0 2.4 2 0 0 2 2 2 0 NTPase NACHT PF05729.12 OQS04056.1 - 0.057 13.3 0.0 2.4 8.0 0.0 2.7 2 0 0 2 2 2 0 NACHT domain AAA_17 PF13207.6 OQS04056.1 - 0.13 12.7 0.3 0.64 10.4 0.0 2.4 2 0 0 2 2 2 0 AAA domain ABC2_membrane PF01061.24 OQS04057.1 - 9.6e-69 231.0 56.2 5.6e-36 123.9 22.7 2.6 3 0 0 3 3 2 2 ABC-2 type transporter ABC_tran PF00005.27 OQS04057.1 - 1.4e-43 148.7 0.7 4.5e-23 82.3 0.0 2.4 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 OQS04057.1 - 8e-11 42.3 1.3 0.013 15.4 0.1 3.4 3 0 0 3 3 3 3 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 OQS04057.1 - 6.5e-09 35.9 0.1 0.00015 21.7 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_29 PF13555.6 OQS04057.1 - 2.8e-08 33.4 0.4 0.0032 17.2 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 OQS04057.1 - 7.8e-08 32.9 0.2 0.0029 18.0 0.0 2.4 2 0 0 2 2 2 2 AAA ATPase domain AAA_23 PF13476.6 OQS04057.1 - 2.2e-07 31.6 1.1 0.0013 19.2 0.2 2.5 2 0 0 2 2 2 2 AAA domain AAA PF00004.29 OQS04057.1 - 2.1e-06 28.2 1.5 0.00027 21.4 0.1 3.3 2 2 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 OQS04057.1 - 9.7e-06 26.2 0.1 0.18 12.3 0.0 2.4 2 0 0 2 2 2 2 AAA domain Rad17 PF03215.15 OQS04057.1 - 3.7e-05 23.7 0.2 0.02 14.9 0.0 2.5 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_22 PF13401.6 OQS04057.1 - 5.5e-05 23.5 1.3 0.13 12.5 0.0 3.0 2 1 0 2 2 2 2 AAA domain SMC_N PF02463.19 OQS04057.1 - 8.1e-05 22.2 0.7 0.019 14.4 0.0 3.3 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 OQS04057.1 - 0.00024 21.2 0.6 0.78 9.8 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_15 PF13175.6 OQS04057.1 - 0.00025 20.9 0.0 0.027 14.2 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain AAA_30 PF13604.6 OQS04057.1 - 0.00025 20.8 0.6 0.065 13.0 0.0 2.5 2 1 0 2 2 2 1 AAA domain cobW PF02492.19 OQS04057.1 - 0.00027 20.6 1.1 0.27 10.8 0.1 2.6 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain NACHT PF05729.12 OQS04057.1 - 0.00036 20.5 0.2 0.31 10.9 0.0 2.6 2 0 0 2 2 2 1 NACHT domain AAA_25 PF13481.6 OQS04057.1 - 0.0004 20.0 0.3 0.34 10.5 0.1 2.4 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.14 OQS04057.1 - 0.0014 18.7 0.5 0.035 14.1 0.0 2.8 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) RNA_helicase PF00910.22 OQS04057.1 - 0.0023 18.3 0.1 0.82 10.1 0.0 3.2 2 1 1 3 3 2 1 RNA helicase AAA_28 PF13521.6 OQS04057.1 - 0.0025 18.1 1.5 0.84 9.9 0.1 2.4 2 0 0 2 2 2 1 AAA domain RuvB_N PF05496.12 OQS04057.1 - 0.0048 16.6 0.0 0.13 12.0 0.0 2.5 2 1 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 OQS04057.1 - 0.0083 16.3 0.3 1.8 8.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 OQS04057.1 - 0.013 14.8 0.2 5 6.4 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin ATPase_2 PF01637.18 OQS04057.1 - 0.023 14.6 0.0 0.36 10.7 0.0 2.4 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea AAA_19 PF13245.6 OQS04057.1 - 0.028 14.8 2.8 0.14 12.5 0.1 2.8 2 1 0 2 2 2 0 AAA domain Roc PF08477.13 OQS04057.1 - 0.029 14.6 0.4 3.1 8.0 0.0 2.7 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase NTPase_1 PF03266.15 OQS04057.1 - 0.059 13.3 1.0 1.5 8.7 0.0 3.0 3 0 0 3 3 3 0 NTPase AAA_11 PF13086.6 OQS04057.1 - 0.064 13.0 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain PduV-EutP PF10662.9 OQS04057.1 - 0.085 12.6 1.0 4.5 7.0 0.0 2.7 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_17 PF13207.6 OQS04057.1 - 0.086 13.3 0.2 23 5.4 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 OQS04057.1 - 0.14 11.9 3.0 4.3 7.0 0.1 3.0 3 0 0 3 3 3 0 AAA domain FeoB_N PF02421.18 OQS04057.1 - 0.14 11.6 0.6 8.9 5.8 0.1 2.5 2 0 0 2 2 2 0 Ferrous iron transport protein B Rieske_2 PF13806.6 OQS04058.1 - 1e-08 35.0 0.0 1.2e-08 34.8 0.0 1.2 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain Rieske PF00355.26 OQS04058.1 - 5.1e-08 32.8 0.2 8.1e-08 32.1 0.2 1.3 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain CAF1C_H4-bd PF12265.8 OQS04059.1 - 6.5e-31 106.4 1.0 7.7e-30 103.0 0.4 2.9 3 0 0 3 3 3 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex WD40 PF00400.32 OQS04059.1 - 9.3e-30 102.3 18.3 2.8e-07 31.1 0.0 5.7 6 0 0 6 6 6 5 WD domain, G-beta repeat eIF2A PF08662.11 OQS04059.1 - 4.6e-06 26.6 0.8 0.00045 20.1 0.0 3.1 3 0 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A ANAPC4_WD40 PF12894.7 OQS04059.1 - 9.5e-05 22.6 1.3 0.051 13.9 0.0 4.0 2 1 3 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain Pkinase PF00069.25 OQS04060.1 - 5.3e-22 78.4 0.0 6e-22 78.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQS04060.1 - 2.7e-19 69.5 0.0 3e-19 69.3 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OQS04060.1 - 0.0012 18.2 0.0 0.0015 17.9 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 OQS04060.1 - 0.1 11.9 0.0 0.15 11.4 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family SMC_Nse1 PF07574.13 OQS04061.1 - 2.3e-17 63.6 0.0 1.3e-12 48.1 0.0 2.1 1 1 1 2 2 2 2 Nse1 non-SMC component of SMC5-6 complex zf-RING-like PF08746.11 OQS04061.1 - 4.6e-09 36.4 8.2 6.4e-09 36.0 8.2 1.2 1 0 0 1 1 1 1 RING-like domain zf-RING_2 PF13639.6 OQS04061.1 - 0.0042 17.4 8.8 0.0061 16.9 8.8 1.3 1 0 0 1 1 1 1 Ring finger domain PyrI_C PF02748.15 OQS04061.1 - 0.045 13.7 1.5 0.091 12.7 1.5 1.5 1 0 0 1 1 1 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain Zn_ribbon_17 PF17120.5 OQS04061.1 - 0.78 9.4 5.2 1.3 8.7 5.2 1.3 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type PHD PF00628.29 OQS04061.1 - 0.9 9.5 7.0 1.4 8.8 7.0 1.3 1 0 0 1 1 1 0 PHD-finger zf-HC5HC2H PF13771.6 OQS04061.1 - 2 8.7 8.2 0.27 11.5 2.6 1.9 1 1 1 2 2 2 0 PHD-like zinc-binding domain Prok-RING_1 PF14446.6 OQS04061.1 - 4.7 7.2 8.8 28 4.8 8.9 1.9 1 1 0 1 1 1 0 Prokaryotic RING finger family 1 zf-CW PF07496.15 OQS04062.1 - 1.3e-26 92.3 17.4 5.5e-17 61.5 10.1 2.6 2 0 0 2 2 2 2 CW-type Zinc Finger FadA PF09403.10 OQS04064.1 - 0.0017 18.8 0.2 0.0029 18.0 0.2 1.4 1 0 0 1 1 1 1 Adhesion protein FadA Rubis-subs-bind PF09273.11 OQS04064.1 - 0.01 16.5 0.1 0.013 16.2 0.1 1.4 1 1 0 1 1 1 0 Rubisco LSMT substrate-binding DUF5082 PF16888.5 OQS04064.1 - 0.1 12.9 1.2 0.21 11.8 1.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5082) ABC_tran_CTD PF16326.5 OQS04064.1 - 0.12 12.7 0.1 0.24 11.7 0.1 1.5 1 0 0 1 1 1 0 ABC transporter C-terminal domain bZIP_1 PF00170.21 OQS04064.1 - 0.12 12.5 5.8 0.21 11.7 5.8 1.4 1 0 0 1 1 1 0 bZIP transcription factor Ank_2 PF12796.7 OQS04065.1 - 5.3e-06 26.9 1.0 9.8e-05 22.9 0.5 1.9 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OQS04065.1 - 2.1e-05 24.7 0.2 0.0023 18.2 0.3 2.2 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 OQS04065.1 - 0.0035 17.9 0.3 6.1 7.5 0.1 2.7 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQS04065.1 - 0.033 14.7 0.1 42 5.2 0.0 3.4 3 0 0 3 3 3 0 Ankyrin repeat Glyco_hydro_6 PF01341.17 OQS04067.1 - 8.5e-88 295.0 18.8 2.2e-44 152.4 3.3 2.8 2 1 0 2 2 2 2 Glycosyl hydrolases family 6 CBM_1 PF00734.18 OQS04067.1 - 7.9e-17 60.9 31.4 6.8e-10 38.7 9.2 4.4 3 0 0 3 3 3 2 Fungal cellulose binding domain PAN_4 PF14295.6 OQS04067.1 - 6.3e-15 54.8 32.8 1.4e-05 24.9 6.6 4.4 4 0 0 4 4 4 3 PAN domain Bact_transglu_N PF08379.10 OQS04067.1 - 0.014 16.2 0.0 5.5 8.0 0.0 3.4 3 0 0 3 3 3 0 Bacterial transglutaminase-like N-terminal region DUF1611 PF07755.11 OQS04067.1 - 0.026 13.8 0.1 4.1 6.6 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1611_C) P-loop domain SAT PF16073.5 OQS04067.1 - 0.038 13.7 1.7 3.2 7.4 0.2 2.3 2 0 0 2 2 2 0 Starter unit:ACP transacylase in aflatoxin biosynthesis PT PF04886.12 OQS04067.1 - 0.18 11.4 72.8 0.026 14.0 10.2 4.7 2 1 1 3 3 3 0 PT repeat DUF5316 PF17247.2 OQS04067.1 - 0.37 10.9 2.1 15 5.6 0.1 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF5316) ORC6 PF05460.13 OQS04067.1 - 1.3 8.2 8.6 2.1 7.5 8.6 1.2 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) FYVE PF01363.21 OQS04068.1 - 0.00016 21.7 15.3 0.00029 20.9 15.3 1.4 1 0 0 1 1 1 1 FYVE zinc finger Bromodomain PF00439.25 OQS04068.1 - 0.021 14.9 0.0 5 7.3 0.0 2.4 2 0 0 2 2 2 0 Bromodomain FYVE_2 PF02318.16 OQS04068.1 - 0.14 12.3 8.7 0.3 11.3 8.7 1.6 1 0 0 1 1 1 0 FYVE-type zinc finger Ras PF00071.22 OQS04073.1 - 1.1e-55 187.7 0.1 1.3e-55 187.5 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OQS04073.1 - 2.9e-33 114.6 0.0 5.1e-33 113.8 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OQS04073.1 - 6.3e-16 58.3 0.0 7.4e-16 58.1 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 OQS04073.1 - 1.3e-07 31.6 0.0 2.1e-07 31.0 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 OQS04073.1 - 4.1e-06 26.3 0.0 5.5e-06 25.9 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 OQS04073.1 - 1.2e-05 25.0 0.0 5.8e-05 22.7 0.0 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 OQS04073.1 - 8.6e-05 22.5 0.0 0.0012 18.7 0.0 2.1 2 0 0 2 2 2 1 RsgA GTPase AAA_16 PF13191.6 OQS04073.1 - 0.0025 18.2 0.0 0.0041 17.5 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 OQS04073.1 - 0.0061 16.8 0.0 0.008 16.5 0.0 1.5 1 1 0 1 1 1 1 AAA domain Septin PF00735.18 OQS04073.1 - 0.0061 15.9 0.1 0.009 15.3 0.1 1.2 1 0 0 1 1 1 1 Septin PduV-EutP PF10662.9 OQS04073.1 - 0.0069 16.1 0.3 0.056 13.2 0.2 2.1 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation SRPRB PF09439.10 OQS04073.1 - 0.009 15.5 0.1 0.026 14.0 0.0 1.7 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit cobW PF02492.19 OQS04073.1 - 0.0092 15.6 0.1 0.021 14.4 0.0 1.7 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_7 PF12775.7 OQS04073.1 - 0.014 14.9 0.0 0.023 14.2 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_24 PF13479.6 OQS04073.1 - 0.029 14.1 0.0 0.055 13.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 OQS04073.1 - 0.066 13.1 0.0 0.1 12.5 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_5 PF07728.14 OQS04073.1 - 0.078 13.0 0.1 0.43 10.6 0.0 2.1 1 1 1 2 2 2 0 AAA domain (dynein-related subfamily) TniB PF05621.11 OQS04073.1 - 0.08 12.3 0.0 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein G-alpha PF00503.20 OQS04073.1 - 0.086 12.0 0.5 0.33 10.1 0.1 1.6 1 1 1 2 2 2 0 G-protein alpha subunit NACHT PF05729.12 OQS04073.1 - 0.094 12.6 0.0 0.17 11.8 0.0 1.4 1 0 0 1 1 1 0 NACHT domain DAP3 PF10236.9 OQS04073.1 - 0.14 11.3 0.1 0.23 10.6 0.1 1.3 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 ABC_tran PF00005.27 OQS04073.1 - 0.14 12.6 0.5 0.31 11.5 0.1 1.8 1 1 0 2 2 2 0 ABC transporter NTPase_1 PF03266.15 OQS04073.1 - 0.16 11.9 0.0 0.22 11.4 0.0 1.2 1 0 0 1 1 1 0 NTPase Cadherin_3 PF16184.5 OQS04074.1 - 0.09 12.8 0.0 0.14 12.2 0.0 1.4 1 0 0 1 1 1 0 Cadherin-like CENP-F_leu_zip PF10473.9 OQS04075.1 - 4.2e-08 33.3 261.3 0.015 15.4 9.3 18.9 4 2 15 20 20 20 11 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Spc7 PF08317.11 OQS04075.1 - 3.2e-06 26.3 272.9 0.0038 16.1 19.3 14.4 4 1 11 16 16 16 10 Spc7 kinetochore protein SHE3 PF17078.5 OQS04075.1 - 1.9e-05 24.5 190.7 7.8e-05 22.5 23.9 12.5 4 1 5 11 11 11 5 SWI5-dependent HO expression protein 3 GAS PF13851.6 OQS04075.1 - 0.00019 20.9 6.8 0.00019 20.9 6.8 17.0 5 2 13 18 18 18 5 Growth-arrest specific micro-tubule binding DUF3584 PF12128.8 OQS04075.1 - 0.00069 17.3 46.9 0.00069 17.3 46.9 9.3 4 1 6 10 10 10 4 Protein of unknown function (DUF3584) FPP PF05911.11 OQS04075.1 - 0.00083 17.7 7.3 0.00083 17.7 7.3 10.5 2 1 8 11 11 11 1 Filament-like plant protein, long coiled-coil PI3K_P85_iSH2 PF16454.5 OQS04075.1 - 0.0034 17.0 4.7 0.0034 17.0 4.7 16.6 3 1 11 14 14 12 6 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain DUF2968 PF11180.8 OQS04075.1 - 0.0052 16.4 2.6 0.0052 16.4 2.6 16.8 3 2 12 18 18 18 3 Protein of unknown function (DUF2968) Filament PF00038.21 OQS04075.1 - 0.022 14.3 211.2 0.011 15.4 9.1 13.2 4 1 8 12 12 12 0 Intermediate filament protein DivIC PF04977.15 OQS04075.1 - 0.029 14.1 0.0 0.029 14.1 0.0 26.0 14 7 12 30 30 29 0 Septum formation initiator ATG16 PF08614.11 OQS04075.1 - 0.045 14.0 282.5 0.049 13.9 22.6 15.3 3 1 11 15 15 15 0 Autophagy protein 16 (ATG16) Colipase-like PF15083.6 OQS04075.1 - 0.54 10.4 3.1 32 4.7 0.1 3.1 2 0 0 2 2 2 0 Colipase-like DUF1664 PF07889.12 OQS04075.1 - 1.1 9.4 156.9 0.057 13.4 7.0 16.8 6 3 14 21 21 21 0 Protein of unknown function (DUF1664) IU_nuc_hydro PF01156.19 OQS04076.1 - 2.5e-64 217.8 0.1 2.8e-64 217.6 0.1 1.0 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase Aminotran_3 PF00202.21 OQS04077.1 - 9.8e-118 393.3 0.0 1.2e-117 393.1 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Beta_elim_lyase PF01212.21 OQS04077.1 - 0.016 14.5 0.0 0.031 13.6 0.0 1.4 1 0 0 1 1 1 0 Beta-eliminating lyase Aminotran_1_2 PF00155.21 OQS04077.1 - 0.018 14.2 0.0 0.028 13.6 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class I and II ARL2_Bind_BART PF11527.8 OQS04078.1 - 2.3e-10 40.6 3.2 1.6e-09 37.9 2.5 2.0 1 1 1 2 2 2 2 The ARF-like 2 binding protein BART Beach PF02138.18 OQS04079.1 - 2.3e-117 391.3 0.0 3.5e-117 390.7 0.0 1.3 1 0 0 1 1 1 1 Beige/BEACH domain PH_BEACH PF14844.6 OQS04079.1 - 4.5e-19 68.4 0.0 1.1e-18 67.1 0.0 1.7 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH WD40 PF00400.32 OQS04079.1 - 5.6e-05 23.8 1.7 0.022 15.6 0.2 4.9 5 0 0 5 5 5 1 WD domain, G-beta repeat DUF2226 PF09987.9 OQS04079.1 - 0.057 12.8 0.0 0.17 11.2 0.0 1.7 1 1 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2226) PTR2 PF00854.21 OQS04080.1 - 2.7e-84 283.3 14.8 5.8e-84 282.2 14.8 1.6 1 1 0 1 1 1 1 POT family MFS_1 PF07690.16 OQS04080.1 - 1.2e-07 31.0 43.9 5.1e-06 25.6 37.3 3.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Peptidase_M13 PF01431.21 OQS04081.1 - 6.1e-141 466.9 12.7 8.3e-50 169.2 0.3 3.8 4 0 0 4 4 4 3 Peptidase family M13 Peptidase_M13_N PF05649.13 OQS04081.1 - 1.4e-129 433.1 11.8 1.8e-68 232.0 0.4 2.3 2 0 0 2 2 2 2 Peptidase family M13 Arf PF00025.21 OQS04081.1 - 2.9e-38 131.1 0.3 3.5e-36 124.3 0.3 2.6 1 1 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 OQS04081.1 - 5.4e-11 42.8 0.1 2.4e-10 40.7 0.1 2.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 OQS04081.1 - 1.7e-09 37.5 0.3 1.7e-09 37.5 0.3 2.2 3 0 0 3 3 3 1 Ras family SRPRB PF09439.10 OQS04081.1 - 2.3e-09 36.9 0.1 5e-09 35.8 0.1 1.5 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 OQS04081.1 - 7.9e-07 29.2 0.0 2.7e-06 27.4 0.0 2.0 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 OQS04081.1 - 2.2e-06 27.2 0.3 5.6e-06 25.9 0.3 1.7 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.20 OQS04081.1 - 1.7e-05 24.2 14.3 6.8e-05 22.2 0.7 3.8 4 1 1 5 5 5 2 G-protein alpha subunit Peptidase_M91 PF14891.6 OQS04081.1 - 0.0006 20.2 0.0 3.2 8.0 0.0 3.4 3 0 0 3 3 3 1 Effector protein DUF1160 PF06648.11 OQS04081.1 - 0.012 15.6 1.2 7.1 6.6 0.3 3.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1160) AAA_18 PF13238.6 OQS04081.1 - 0.1 13.1 0.0 0.25 11.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain TPR_2 PF07719.17 OQS04082.1 - 2.5e-14 52.2 5.9 4.1e-05 23.4 0.5 3.5 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.28 OQS04082.1 - 1.2e-12 47.1 5.8 0.00074 19.2 0.2 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 OQS04082.1 - 4.7e-06 26.2 6.0 0.00041 20.0 0.1 3.1 2 1 2 4 4 4 2 TPR repeat TPR_8 PF13181.6 OQS04082.1 - 6.3e-05 22.9 5.6 0.012 15.8 0.3 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.6 OQS04082.1 - 9.6e-05 22.6 4.7 0.0058 16.9 1.5 3.2 1 1 2 3 3 3 2 Tetratricopeptide repeat Bap31_Bap29_C PF18035.1 OQS04082.1 - 0.00013 21.9 3.0 0.00033 20.6 3.0 1.7 1 0 0 1 1 1 1 Bap31/Bap29 cytoplasmic coiled-coil domain TPR_10 PF13374.6 OQS04082.1 - 0.00072 19.3 3.2 0.00079 19.2 0.7 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.6 OQS04082.1 - 0.017 15.1 1.1 5.5 7.3 0.1 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_9 PF13371.6 OQS04082.1 - 0.06 13.5 1.0 2 8.7 0.1 2.2 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 OQS04082.1 - 0.25 12.3 5.2 0.84 10.6 0.5 3.4 2 1 2 4 4 4 0 Tetratricopeptide repeat TPR_16 PF13432.6 OQS04082.1 - 0.36 11.5 6.7 0.71 10.6 0.5 2.5 2 1 1 3 3 3 0 Tetratricopeptide repeat MIT PF04212.18 OQS04082.1 - 8.4 6.5 9.9 4.3 7.5 0.1 3.1 2 1 0 2 2 2 0 MIT (microtubule interacting and transport) domain IFT43 PF15305.6 OQS04083.1 - 7.4e-30 103.9 5.1 7.4e-30 103.9 5.1 1.4 2 0 0 2 2 2 1 Intraflagellar transport protein 43 Cation_efflux PF01545.21 OQS04084.1 - 1.6e-48 165.1 5.1 1.9e-48 164.9 5.1 1.1 1 0 0 1 1 1 1 Cation efflux family DUF4064 PF13273.6 OQS04084.1 - 0.04 14.2 7.6 0.076 13.3 6.2 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF4064) FAM76 PF16046.5 OQS04084.1 - 0.14 11.5 0.1 0.2 11.0 0.1 1.1 1 0 0 1 1 1 0 FAM76 protein Epiglycanin_C PF14654.6 OQS04084.1 - 3.3 7.8 6.4 7.6 6.7 5.9 1.9 2 0 0 2 2 2 0 Mucin, catalytic, TM and cytoplasmic tail region Importin_rep_2 PF18786.1 OQS04084.1 - 7.6 6.5 6.3 5.1 7.0 1.9 2.8 2 0 0 2 2 2 0 Importin 13 repeat CSRNP_N PF16019.5 OQS04085.1 - 0.002 18.1 1.1 0.0053 16.7 1.1 1.7 1 1 0 1 1 1 1 Cysteine/serine-rich nuclear protein N-terminus Enkurin PF13864.6 OQS04085.1 - 0.035 14.5 1.7 0.056 13.9 1.2 1.6 1 1 0 1 1 1 0 Calmodulin-binding Nup_retrotrp_bd PF10599.9 OQS04085.1 - 0.12 13.0 0.0 0.24 12.1 0.0 1.5 1 0 0 1 1 1 0 Retro-transposon transporting motif CW_7 PF08230.11 OQS04085.1 - 0.15 11.8 0.0 0.3 10.9 0.0 1.5 1 0 0 1 1 1 0 CW_7 repeat DUF866 PF05907.13 OQS04086.1 - 2.7e-40 137.8 0.0 3e-40 137.7 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF866) Nucleoside_tran PF01733.18 OQS04087.1 - 4.5e-33 115.0 41.3 5.1e-17 62.2 12.8 4.2 2 2 1 3 3 3 3 Nucleoside transporter MFS_1 PF07690.16 OQS04087.1 - 8.3e-12 44.7 82.1 2.6e-08 33.2 28.3 3.9 2 2 1 3 3 3 3 Major Facilitator Superfamily DUF4501 PF14946.6 OQS04087.1 - 0.013 15.6 0.1 3.7 7.6 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4501) Ank_2 PF12796.7 OQS04088.1 - 2.9e-20 72.6 0.5 3.1e-08 34.1 0.1 4.3 2 1 2 4 4 4 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OQS04088.1 - 1.5e-19 69.8 1.8 1.1e-05 25.6 0.0 4.5 3 2 1 4 4 4 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 OQS04088.1 - 1.1e-14 54.5 0.4 2.7e-07 31.0 0.0 4.9 3 2 1 4 4 4 2 Ankyrin repeats (many copies) RGS PF00615.19 OQS04088.1 - 1.3e-12 48.0 3.9 1.7e-11 44.4 0.7 2.7 2 0 0 2 2 2 1 Regulator of G protein signaling domain Ank_3 PF13606.6 OQS04088.1 - 4.6e-11 41.9 3.5 0.0023 18.3 0.0 6.0 5 0 0 5 5 5 2 Ankyrin repeat Ank PF00023.30 OQS04088.1 - 5.2e-08 33.0 1.0 0.14 12.6 0.1 4.9 4 0 0 4 4 4 2 Ankyrin repeat TPR_12 PF13424.6 OQS04088.1 - 8.5e-06 26.0 0.1 6e-05 23.3 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_10 PF13374.6 OQS04088.1 - 0.00014 21.6 0.1 0.00097 18.9 0.0 2.7 2 0 0 2 2 1 1 Tetratricopeptide repeat TPR_2 PF07719.17 OQS04088.1 - 0.00063 19.7 0.4 1.4 9.2 0.0 3.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_21 PF09976.9 OQS04088.1 - 0.0077 16.0 0.0 0.021 14.5 0.0 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat-like domain zf-B_box PF00643.24 OQS04088.1 - 0.012 15.8 13.4 0.039 14.1 13.4 1.9 1 0 0 1 1 1 0 B-box zinc finger Taeniidae_ag PF05596.11 OQS04088.1 - 0.067 13.2 1.3 0.18 11.8 0.0 2.4 3 0 0 3 3 3 0 Taeniidae antigen DUF3239 PF11580.8 OQS04088.1 - 0.068 13.5 1.3 20 5.5 0.0 3.0 2 1 0 2 2 2 0 Protein of unknown function (DUF3239) CEBP_ZZ PF16366.5 OQS04088.1 - 0.41 10.9 8.5 0.97 9.7 8.5 1.6 1 0 0 1 1 1 0 Cytoplasmic polyadenylation element-binding protein ZZ domain Adaptin_N PF01602.20 OQS04089.1 - 1.5e-112 376.8 0.4 1.8e-112 376.6 0.4 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptin_C PF02296.16 OQS04089.1 - 9.6e-17 61.2 0.0 2.7e-16 59.8 0.0 1.8 1 0 0 1 1 1 1 Alpha adaptin AP2, C-terminal domain Alpha_adaptinC2 PF02883.20 OQS04089.1 - 1.5e-15 57.4 1.5 2.9e-15 56.5 1.5 1.4 1 0 0 1 1 1 1 Adaptin C-terminal domain Cnd1 PF12717.7 OQS04089.1 - 1.1e-05 25.5 0.9 0.0002 21.5 0.0 2.8 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 Proteasom_PSMB PF10508.9 OQS04089.1 - 0.0061 15.1 0.5 0.011 14.3 0.5 1.3 1 0 0 1 1 1 1 Proteasome non-ATPase 26S subunit HEAT PF02985.22 OQS04089.1 - 0.014 15.6 1.5 10 6.7 0.1 3.7 3 0 0 3 3 3 0 HEAT repeat PBP_GOBP PF01395.22 OQS04089.1 - 0.015 15.5 4.4 1.6 9.0 0.2 3.3 3 0 0 3 3 3 0 PBP/GOBP family KfrB PF18790.1 OQS04089.1 - 0.057 13.7 0.1 0.12 12.6 0.1 1.5 1 0 0 1 1 1 0 KfrB protein B2-adapt-app_C PF09066.10 OQS04089.1 - 0.12 12.5 0.6 82 3.3 0.1 3.6 3 0 0 3 3 3 0 Beta2-adaptin appendage, C-terminal sub-domain eIF-3c_N PF05470.12 OQS04090.1 - 2e-146 488.8 40.8 7.1e-145 483.7 40.8 2.8 1 1 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 8 N-terminus PCI PF01399.27 OQS04090.1 - 2e-09 37.9 0.0 1.5e-08 35.1 0.0 2.4 2 0 0 2 2 2 1 PCI domain PAN_4 PF14295.6 OQS04091.1 - 1e-07 31.7 2.0 3e-07 30.2 2.0 1.8 1 0 0 1 1 1 1 PAN domain Use1 PF09753.9 OQS04092.1 - 2.4e-20 73.3 0.9 3.3e-20 72.8 0.9 1.2 1 0 0 1 1 1 1 Membrane fusion protein Use1 Acetyltransf_9 PF13527.7 OQS04092.1 - 4.4e-17 62.3 0.0 1.4e-16 60.7 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 OQS04092.1 - 2.6e-07 31.0 0.0 7.9e-07 29.4 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 OQS04092.1 - 8.5e-05 22.8 0.0 0.00031 21.0 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 OQS04092.1 - 0.004 17.1 0.0 0.091 12.7 0.0 2.5 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 OQS04092.1 - 0.0088 16.0 0.0 0.021 14.8 0.0 1.6 1 0 0 1 1 1 1 FR47-like protein Ccdc124 PF06244.12 OQS04093.1 - 2.7e-28 99.1 22.3 1.5e-26 93.4 22.3 2.3 1 1 0 1 1 1 1 Coiled-coil domain-containing protein 124 /Oxs1 DUF3889 PF13028.6 OQS04093.1 - 0.1 12.5 0.1 0.1 12.5 0.1 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3889) CCDC106 PF15794.5 OQS04093.1 - 8.5 6.0 13.8 12 5.5 11.0 2.1 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 106 MAT1 PF06391.13 OQS04093.1 - 8.9 6.1 12.2 2.8 7.7 9.2 1.6 2 0 0 2 2 2 0 CDK-activating kinase assembly factor MAT1 Spc7 PF08317.11 OQS04094.1 - 0.082 11.8 20.8 0.016 14.1 3.0 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein DUF3228 PF11539.8 OQS04094.1 - 0.087 12.3 5.1 5.8 6.4 0.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3228) CUTL PF16557.5 OQS04094.1 - 0.091 12.9 3.5 0.33 11.2 0.2 2.7 2 1 0 3 3 3 0 CUT1-like DNA-binding domain of SATB DUF1664 PF07889.12 OQS04094.1 - 0.099 12.7 14.5 0.21 11.6 2.6 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) BRE1 PF08647.11 OQS04094.1 - 0.12 12.5 22.5 0.52 10.4 12.2 2.3 1 1 1 2 2 2 0 BRE1 E3 ubiquitin ligase V_ATPase_I PF01496.19 OQS04094.1 - 0.31 8.9 10.3 0.37 8.6 10.3 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family ATG16 PF08614.11 OQS04094.1 - 0.39 10.9 19.1 1.5 9.0 15.7 1.9 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) APG6_N PF17675.1 OQS04094.1 - 0.52 10.8 22.7 0.1 13.1 3.4 2.2 1 1 1 2 2 2 0 Apg6 coiled-coil region Fez1 PF06818.15 OQS04094.1 - 0.57 10.6 17.9 7.2 7.0 17.9 2.0 1 1 0 1 1 1 0 Fez1 LMBR1 PF04791.16 OQS04094.1 - 0.64 8.9 9.7 0.77 8.6 9.7 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein Occludin_ELL PF07303.13 OQS04094.1 - 1.6 9.5 9.3 0.17 12.6 0.9 2.4 1 1 1 2 2 2 0 Occludin homology domain DUF2115 PF09888.9 OQS04094.1 - 1.8 9.1 7.4 0.29 11.6 1.3 2.0 1 1 1 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2115) DUF724 PF05266.14 OQS04094.1 - 1.8 8.4 18.0 1.1 9.0 0.9 2.1 1 1 0 2 2 2 0 Protein of unknown function (DUF724) YabA PF06156.13 OQS04094.1 - 2.4 8.9 13.4 0.63 10.7 7.8 2.3 1 1 1 2 2 2 0 Initiation control protein YabA DivIC PF04977.15 OQS04094.1 - 3.2 7.6 16.2 0.18 11.6 2.8 3.0 2 2 1 3 3 3 0 Septum formation initiator KLRAQ PF10205.9 OQS04094.1 - 4.8 7.5 16.7 0.67 10.2 2.5 2.3 1 1 0 2 2 2 0 Predicted coiled-coil domain-containing protein CCDC-167 PF15188.6 OQS04094.1 - 5 7.5 18.7 2.7 8.4 12.2 2.6 1 1 1 2 2 2 0 Coiled-coil domain-containing protein 167 CC2-LZ PF16516.5 OQS04094.1 - 5.9 7.3 15.4 0.42 11.0 1.4 2.6 1 1 0 2 2 2 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator zf-C4H2 PF10146.9 OQS04094.1 - 8.8 6.6 20.0 2.5e+02 1.8 20.0 2.3 1 1 0 1 1 1 0 Zinc finger-containing protein DUF4200 PF13863.6 OQS04094.1 - 9.3 6.7 20.9 8.5 6.8 3.2 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) Armet PF10208.9 OQS04095.1 - 1.4e-22 80.2 5.4 3.2e-22 79.0 5.4 1.5 1 1 0 1 1 1 1 Degradation arginine-rich protein for mis-folding SAP PF02037.27 OQS04095.1 - 1.1e-05 25.1 0.4 2.8e-05 23.7 0.4 1.8 1 0 0 1 1 1 1 SAP domain HeH PF12949.7 OQS04095.1 - 0.0028 17.3 0.0 0.0068 16.1 0.0 1.7 1 0 0 1 1 1 1 HeH/LEM domain Kinesin_assoc PF16183.5 OQS04095.1 - 0.055 13.6 0.0 0.084 13.0 0.0 1.3 1 1 0 1 1 1 0 Kinesin-associated Fungus-induced PF10917.8 OQS04095.1 - 0.17 12.2 0.0 0.28 11.5 0.0 1.4 1 0 0 1 1 1 0 Fungus-induced protein DPBB_1 PF03330.18 OQS04096.1 - 2.5e-07 30.9 0.1 6.6e-07 29.5 0.1 1.7 1 0 0 1 1 1 1 Lytic transglycolase Barwin PF00967.17 OQS04096.1 - 0.00056 19.7 0.0 0.0011 18.9 0.0 1.5 1 0 0 1 1 1 1 Barwin family Orf78 PF06024.12 OQS04096.1 - 0.13 12.5 0.0 0.24 11.7 0.0 1.3 1 0 0 1 1 1 0 Orf78 (ac78) DUF4366 PF14283.6 OQS04096.1 - 1.3 9.1 6.7 26 4.8 6.7 2.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4366) DUF2057 PF09829.9 OQS04097.1 - 0.046 13.9 2.4 0.081 13.1 2.4 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2057) FYVE PF01363.21 OQS04098.1 - 5.6e-14 52.0 14.2 1.3e-13 50.9 14.2 1.6 1 0 0 1 1 1 1 FYVE zinc finger Epimerase PF01370.21 OQS04098.1 - 4.1e-12 46.1 0.0 1.5e-11 44.2 0.0 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 OQS04098.1 - 2e-11 44.1 0.0 3.3e-11 43.4 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 OQS04098.1 - 6.1e-06 25.4 0.0 1.1e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 OQS04098.1 - 0.00049 19.6 0.0 0.0044 16.5 0.0 2.2 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase NmrA PF05368.13 OQS04098.1 - 0.015 14.9 0.0 0.34 10.4 0.0 2.7 2 1 0 2 2 2 0 NmrA-like family FYVE_2 PF02318.16 OQS04098.1 - 0.21 11.8 7.7 0.59 10.4 7.7 1.7 1 0 0 1 1 1 0 FYVE-type zinc finger DUF2688 PF10892.8 OQS04098.1 - 0.35 10.4 6.0 0.075 12.5 2.5 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF2688) CFAP91 PF14738.6 OQS04099.1 - 3.3e-56 189.6 9.6 3.3e-56 189.6 9.6 2.1 2 0 0 2 2 2 1 Cilia- and flagella-associated protein 91 Amino_oxidase PF01593.24 OQS04099.1 - 2.9e-39 135.6 0.0 7.5e-39 134.3 0.0 1.7 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 OQS04099.1 - 2.5e-13 50.0 0.1 5.7e-13 48.9 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 OQS04099.1 - 0.00099 19.1 0.1 0.0049 16.9 0.1 2.2 1 0 0 1 1 1 1 FAD-NAD(P)-binding DAO PF01266.24 OQS04099.1 - 0.0019 17.9 0.1 0.0047 16.6 0.1 1.7 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 OQS04099.1 - 0.0063 15.8 0.0 0.14 11.3 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 OQS04099.1 - 0.051 12.4 0.3 0.093 11.6 0.3 1.4 1 0 0 1 1 1 0 Tryptophan halogenase Pyr_redox PF00070.27 OQS04099.1 - 0.1 13.2 0.5 0.55 10.8 0.2 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 OQS04099.1 - 0.11 11.8 3.0 0.099 11.9 0.2 2.4 3 0 0 3 3 3 0 Thi4 family ArfGap PF01412.18 OQS04100.1 - 6.1e-31 106.9 0.1 1.3e-30 105.8 0.1 1.6 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf Ribosomal_S9 PF00380.19 OQS04102.1 - 7.9e-48 162.0 0.3 2.6e-47 160.3 0.1 1.8 2 0 0 2 2 2 1 Ribosomal protein S9/S16 CDC48_N PF02359.18 OQS04102.1 - 0.11 12.7 0.0 0.23 11.7 0.0 1.5 1 0 0 1 1 1 0 Cell division protein 48 (CDC48), N-terminal domain BTB PF00651.31 OQS04103.1 - 7.7e-22 77.6 1.6 3.9e-21 75.4 0.3 2.6 1 1 1 2 2 2 1 BTB/POZ domain FYVE PF01363.21 OQS04103.1 - 1.5e-16 60.2 11.6 3.6e-16 59.0 11.6 1.6 1 0 0 1 1 1 1 FYVE zinc finger NAD_binding_10 PF13460.6 OQS04103.1 - 3.9e-10 39.9 0.0 6.8e-10 39.1 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 OQS04103.1 - 0.00012 21.7 0.0 0.0011 18.5 0.0 2.6 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family Arm PF00514.23 OQS04103.1 - 0.00049 20.0 0.0 0.005 16.8 0.0 2.7 3 0 0 3 3 3 1 Armadillo/beta-catenin-like repeat 3Beta_HSD PF01073.19 OQS04103.1 - 0.0071 15.4 0.0 0.016 14.2 0.0 1.7 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Sulfotransfer_4 PF17784.1 OQS04103.1 - 0.011 15.6 0.0 0.67 9.8 0.0 2.4 2 0 0 2 2 2 0 Sulfotransferase domain FYVE_2 PF02318.16 OQS04103.1 - 0.043 14.0 10.7 0.029 14.6 7.9 2.1 2 0 0 2 2 2 0 FYVE-type zinc finger BTB_2 PF02214.22 OQS04103.1 - 0.069 13.5 0.1 0.22 11.9 0.1 1.8 1 0 0 1 1 1 0 BTB/POZ domain TruB_N PF01509.18 OQS04104.1 - 3.3e-42 144.4 0.3 2.5e-41 141.5 0.3 2.0 1 1 0 1 1 1 1 TruB family pseudouridylate synthase (N terminal domain) PseudoU_synth_2 PF00849.22 OQS04104.1 - 0.022 14.9 0.0 0.035 14.2 0.0 1.3 1 1 0 1 1 1 0 RNA pseudouridylate synthase TruB_C_2 PF16198.5 OQS04104.1 - 0.047 13.8 0.1 0.2 11.8 0.0 2.1 2 0 0 2 2 2 0 tRNA pseudouridylate synthase B C-terminal domain Ion_trans PF00520.31 OQS04106.1 - 1.2e-44 152.4 44.9 1.3e-23 83.5 17.1 2.4 2 0 0 2 2 2 2 Ion transport protein Pkinase PF00069.25 OQS04106.1 - 6e-22 78.3 0.0 1.4e-21 77.1 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Ion_trans_2 PF07885.16 OQS04106.1 - 6.9e-22 77.2 25.8 5e-13 48.8 9.2 3.6 3 1 0 3 3 3 2 Ion channel Pkinase_Tyr PF07714.17 OQS04106.1 - 4.9e-21 75.2 0.1 1.3e-20 73.8 0.1 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase cNMP_binding PF00027.29 OQS04106.1 - 5.5e-16 58.4 0.1 4e-07 30.0 0.0 3.1 3 0 0 3 3 3 2 Cyclic nucleotide-binding domain LRR_8 PF13855.6 OQS04106.1 - 0.0005 19.8 6.2 0.0012 18.6 6.2 1.7 1 0 0 1 1 1 1 Leucine rich repeat RIO1 PF01163.22 OQS04106.1 - 0.012 15.2 0.0 0.028 14.0 0.0 1.5 1 0 0 1 1 1 0 RIO1 family LRR_4 PF12799.7 OQS04106.1 - 0.014 15.8 1.0 0.014 15.8 1.0 3.0 1 1 1 3 3 3 0 Leucine Rich repeats (2 copies) TMEM154 PF15102.6 OQS04106.1 - 0.031 14.2 0.3 1.1 9.1 0.0 2.3 2 0 0 2 2 2 0 TMEM154 protein family IRK PF01007.20 OQS04106.1 - 0.66 9.8 14.1 3 7.6 6.5 2.8 2 0 0 2 2 2 0 Inward rectifier potassium channel transmembrane domain DUF2207 PF09972.9 OQS04106.1 - 1.3 7.6 10.7 0.72 8.5 0.0 2.8 3 0 0 3 3 3 0 Predicted membrane protein (DUF2207) LRR_6 PF13516.6 OQS04106.1 - 2.9 8.2 6.7 5.9 7.2 0.0 3.3 3 0 0 3 3 3 0 Leucine Rich repeat YrhK PF14145.6 OQS04107.1 - 1.5e-18 66.4 25.8 7.2e-09 35.4 2.5 3.2 3 0 0 3 3 3 3 YrhK-like protein Fasciclin PF02469.22 OQS04108.1 - 0.029 14.6 5.0 12 6.1 0.2 3.8 3 0 0 3 3 3 0 Fasciclin domain DUF5605 PF18310.1 OQS04108.1 - 0.064 13.1 0.0 83 3.2 0.0 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF5605) Dna2 PF08696.11 OQS04108.1 - 0.098 12.4 7.9 2.6 7.8 0.6 3.7 3 1 0 3 3 3 0 DNA replication factor Dna2 Elicitin PF00964.17 OQS04110.1 - 0.013 15.6 1.0 0.019 15.1 1.0 1.3 1 0 0 1 1 1 0 Elicitin LVIVD PF08309.11 OQS04111.1 - 1e-06 27.9 7.1 0.0068 15.7 0.0 4.4 4 0 0 4 4 4 3 LVIVD repeat Nup160 PF11715.8 OQS04111.1 - 0.018 13.8 0.0 0.13 10.8 0.0 2.2 2 0 0 2 2 2 0 Nucleoporin Nup120/160 PQQ_2 PF13360.6 OQS04111.1 - 0.028 14.0 0.0 0.045 13.3 0.0 1.3 1 0 0 1 1 1 0 PQQ-like domain PQQ_3 PF13570.6 OQS04111.1 - 2.6 8.7 4.0 16 6.2 0.1 3.5 4 0 0 4 4 4 0 PQQ-like domain SpoU_methylase PF00588.19 OQS04112.1 - 1.5e-29 103.0 0.1 2.8e-29 102.1 0.0 1.5 2 0 0 2 2 2 1 SpoU rRNA Methylase family SpoU_sub_bind PF08032.12 OQS04112.1 - 5.2e-13 49.1 0.0 1.4e-12 47.7 0.0 1.7 2 0 0 2 2 2 1 RNA 2'-O ribose methyltransferase substrate binding BTB PF00651.31 OQS04112.1 - 0.013 15.8 0.0 0.52 10.6 0.0 2.7 3 0 0 3 3 3 0 BTB/POZ domain Pkinase PF00069.25 OQS04113.1 - 3.8e-59 200.2 0.0 5.8e-59 199.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQS04113.1 - 2.5e-44 151.5 0.1 7.5e-44 149.9 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OQS04113.1 - 3.2e-07 29.5 0.0 5.3e-07 28.8 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 OQS04113.1 - 1.1e-05 24.9 0.0 1.9e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 OQS04113.1 - 0.00045 19.6 1.3 0.0016 17.8 0.2 2.1 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family SCP1201-deam PF14428.6 OQS04113.1 - 0.11 12.4 0.0 0.2 11.5 0.0 1.4 1 0 0 1 1 1 0 SCP1.201-like deaminase MIT PF04212.18 OQS04114.1 - 1.7e-07 31.2 3.5 5.5e-07 29.6 3.5 2.0 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain TPR_2 PF07719.17 OQS04114.1 - 0.28 11.4 3.1 5.8 7.3 0.3 3.0 1 1 1 2 2 2 0 Tetratricopeptide repeat DHHA1 PF02272.19 OQS04114.1 - 0.89 10.0 5.6 0.66 10.4 1.3 2.4 2 0 0 2 2 2 0 DHHA1 domain G-gamma PF00631.22 OQS04114.1 - 3.1 7.8 6.8 16 5.6 0.1 3.5 3 0 0 3 3 3 0 GGL domain Actin PF00022.19 OQS04115.1 - 2.6e-113 378.7 0.0 2.2e-112 375.6 0.0 1.9 1 1 0 1 1 1 1 Actin Asn_synthase PF00733.21 OQS04116.1 - 2.4e-27 96.6 0.0 4.6e-20 72.6 0.0 2.2 1 1 1 2 2 2 2 Asparagine synthase MMACHC PF16690.5 OQS04116.1 - 8e-12 45.3 0.1 9.5e-11 41.8 0.1 2.3 1 1 0 1 1 1 1 Methylmalonic aciduria and homocystinuria type C family DZR PF12773.7 OQS04116.1 - 0.021 14.9 0.5 0.042 13.9 0.5 1.4 1 0 0 1 1 1 0 Double zinc ribbon NAD_synthase PF02540.17 OQS04116.1 - 0.026 13.7 0.0 0.057 12.5 0.0 1.5 2 0 0 2 2 2 0 NAD synthase zf-ribbon_3 PF13248.6 OQS04116.1 - 0.029 13.8 2.0 0.053 12.9 2.0 1.4 1 0 0 1 1 1 0 zinc-ribbon domain tRNA_Me_trans PF03054.16 OQS04116.1 - 0.049 12.4 0.0 0.47 9.2 0.0 2.0 2 0 0 2 2 2 0 tRNA methyl transferase zinc_ribbon_2 PF13240.6 OQS04116.1 - 1.2 8.9 2.8 2.1 8.2 2.8 1.4 1 0 0 1 1 1 0 zinc-ribbon domain TRP PF06011.12 OQS04117.1 - 2.7e-05 23.1 36.0 0.00011 21.1 36.0 1.8 1 1 0 1 1 1 1 Transient receptor potential (TRP) ion channel ATP-synt_ab PF00006.25 OQS04118.1 - 5.8e-67 225.4 0.0 7.8e-67 225.0 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 OQS04118.1 - 3.1e-12 46.8 0.5 5.8e-12 46.0 0.5 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain Myb_DNA-binding PF00249.31 OQS04119.1 - 0.00056 20.0 0.1 0.0026 17.9 0.0 2.1 2 0 0 2 2 2 1 Myb-like DNA-binding domain SSXT PF05030.12 OQS04119.1 - 0.00099 18.7 1.4 0.0021 17.7 1.4 1.5 1 0 0 1 1 1 1 SSXT protein (N-terminal region) CPBP PF02517.16 OQS04121.1 - 4.4e-08 33.4 14.3 4.4e-08 33.4 14.3 2.8 2 1 0 2 2 2 1 CPBP intramembrane metalloprotease Ank_2 PF12796.7 OQS04122.1 - 1.2e-25 89.9 4.0 1.2e-10 41.8 0.1 3.4 1 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OQS04122.1 - 1.2e-20 71.4 7.1 9.9e-05 22.5 0.1 6.0 5 1 1 6 6 6 5 Ankyrin repeat Ank_5 PF13857.6 OQS04122.1 - 1.9e-18 66.3 6.0 2.1e-05 24.7 0.1 4.5 2 2 3 5 5 5 4 Ankyrin repeats (many copies) Ank PF00023.30 OQS04122.1 - 2.9e-17 62.2 14.1 0.00012 22.3 0.4 6.0 5 1 1 6 6 6 4 Ankyrin repeat Ank_4 PF13637.6 OQS04122.1 - 1.6e-16 60.4 4.3 0.0025 18.4 0.1 4.1 3 1 1 4 4 4 4 Ankyrin repeats (many copies) Imm_superinfect PF14373.6 OQS04122.1 - 0.26 11.3 6.4 10 6.1 0.0 4.3 4 1 1 5 5 5 0 Superinfection immunity protein K-box PF01486.17 OQS04123.1 - 0.00097 19.3 0.9 0.0012 19.0 0.9 1.2 1 0 0 1 1 1 1 K-box region HALZ PF02183.18 OQS04123.1 - 0.0041 17.3 0.4 0.0091 16.2 0.4 1.6 1 0 0 1 1 1 1 Homeobox associated leucine zipper TPR_MLP1_2 PF07926.12 OQS04123.1 - 0.0042 17.2 2.9 0.0042 17.2 2.9 1.3 2 0 0 2 2 2 1 TPR/MLP1/MLP2-like protein DUF5320 PF17253.2 OQS04123.1 - 0.014 16.4 1.9 0.022 15.8 0.9 1.6 1 1 1 2 2 2 0 Family of unknown function (DUF5320) FlaC_arch PF05377.11 OQS04123.1 - 0.015 15.7 0.7 0.1 13.0 0.1 2.2 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) DUF2390 PF09523.10 OQS04123.1 - 0.02 15.2 0.5 0.024 15.0 0.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2390) Miff PF05644.11 OQS04123.1 - 0.024 14.3 0.3 0.028 14.1 0.3 1.1 1 0 0 1 1 1 0 Mitochondrial and peroxisomal fission factor Mff DUF1840 PF08895.11 OQS04123.1 - 0.041 14.2 0.9 0.043 14.1 0.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1840) DUF1117 PF06547.12 OQS04123.1 - 0.059 13.9 0.3 0.07 13.7 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1117) YbjQ_1 PF01906.17 OQS04123.1 - 0.062 13.9 0.1 0.093 13.4 0.1 1.3 1 0 0 1 1 1 0 Putative heavy-metal-binding MbeD_MobD PF04899.12 OQS04123.1 - 0.11 12.7 2.6 1.2 9.3 2.6 2.1 1 1 0 1 1 1 0 MbeD/MobD like ZapB PF06005.12 OQS04123.1 - 0.17 12.3 5.1 0.15 12.5 3.8 1.7 2 1 0 2 2 2 0 Cell division protein ZapB DivIC PF04977.15 OQS04123.1 - 0.92 9.3 5.8 0.61 9.9 1.4 2.1 1 1 1 2 2 2 0 Septum formation initiator Arm PF00514.23 OQS04124.1 - 3.8e-81 264.9 17.7 2.7e-12 46.3 0.0 9.1 8 0 0 8 8 8 8 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 OQS04124.1 - 2.6e-20 72.5 0.1 8.4e-08 32.6 0.0 6.2 5 0 0 5 5 5 3 HEAT-like repeat zf-UBR PF02207.20 OQS04124.1 - 3.6e-17 62.3 19.0 4.6e-17 61.9 17.4 2.0 2 0 0 2 2 2 1 Putative zinc finger in N-recognin (UBR box) HEAT_2 PF13646.6 OQS04124.1 - 3.6e-17 62.5 0.1 1.5e-05 25.3 0.0 5.3 4 2 1 5 5 5 3 HEAT repeats IBB PF01749.20 OQS04124.1 - 4.8e-17 62.2 2.0 9.6e-17 61.2 2.0 1.5 1 0 0 1 1 1 1 Importin beta binding domain Arm_3 PF16186.5 OQS04124.1 - 2.9e-16 58.8 0.0 9.7e-16 57.1 0.2 1.8 2 0 0 2 2 2 1 Atypical Arm repeat HEAT PF02985.22 OQS04124.1 - 1.4e-13 49.9 2.6 0.00023 21.2 0.0 7.3 8 0 0 8 8 8 3 HEAT repeat Adaptin_N PF01602.20 OQS04124.1 - 0.00031 19.5 0.0 0.032 12.8 0.0 2.6 1 1 1 2 2 2 2 Adaptin N terminal region Arm_2 PF04826.13 OQS04124.1 - 0.003 17.1 0.7 2.2 7.6 0.0 3.6 2 1 2 4 4 4 1 Armadillo-like IFRD PF05004.13 OQS04124.1 - 0.0049 16.0 0.1 0.058 12.5 0.0 2.6 2 0 0 2 2 2 1 Interferon-related developmental regulator (IFRD) V-ATPase_H_C PF11698.8 OQS04124.1 - 0.028 14.5 0.0 0.94 9.6 0.0 3.5 4 0 0 4 4 4 0 V-ATPase subunit H HEAT_PBS PF03130.16 OQS04124.1 - 0.036 14.7 0.0 4.4 8.3 0.1 4.1 4 0 0 4 4 3 0 PBS lyase HEAT-like repeat GSHPx PF00255.19 OQS04125.1 - 4.4e-22 77.7 0.0 5.5e-22 77.4 0.0 1.1 1 0 0 1 1 1 1 Glutathione peroxidase LRR_6 PF13516.6 OQS04126.1 - 2.2e-07 30.4 11.9 0.019 15.0 0.1 7.2 8 0 0 8 8 8 2 Leucine Rich repeat LRR_1 PF00560.33 OQS04126.1 - 0.0012 19.1 10.7 21 6.2 0.0 7.3 7 1 0 7 7 7 1 Leucine Rich Repeat FAE1_CUT1_RppA PF08392.12 OQS04126.1 - 0.11 11.8 0.0 0.18 11.0 0.0 1.4 1 0 0 1 1 1 0 FAE1/Type III polyketide synthase-like protein Suc_Fer-like PF06999.12 OQS04126.1 - 0.13 12.1 0.0 0.28 11.0 0.0 1.5 1 0 0 1 1 1 0 Sucrase/ferredoxin-like PilN PF05137.13 OQS04126.1 - 0.13 12.4 0.0 9.4 6.4 0.0 2.5 2 0 0 2 2 2 0 Fimbrial assembly protein (PilN) LRR_4 PF12799.7 OQS04126.1 - 1.1 9.7 18.0 7.7 7.1 0.4 6.1 4 2 3 7 7 7 0 Leucine Rich repeats (2 copies) BOP1NT PF08145.12 OQS04127.1 - 4.4e-107 357.8 3.7 4.4e-107 357.8 3.7 1.8 2 0 0 2 2 2 1 BOP1NT (NUC169) domain WD40 PF00400.32 OQS04127.1 - 1.8e-26 91.8 9.8 6.2e-07 30.0 0.0 7.4 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OQS04127.1 - 4.4e-10 39.7 0.2 0.00015 22.0 0.1 5.4 3 1 1 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 OQS04127.1 - 0.0065 15.2 0.0 0.011 14.4 0.0 1.3 1 0 0 1 1 1 1 Nucleoporin Nup120/160 Frtz PF11768.8 OQS04127.1 - 0.034 12.5 0.1 2.2 6.5 0.0 2.1 2 0 0 2 2 2 0 WD repeat-containing and planar cell polarity effector protein Fritz SDA1 PF05285.12 OQS04127.1 - 0.04 13.3 20.5 0.064 12.7 20.5 1.4 1 0 0 1 1 1 0 SDA1 YL1 PF05764.13 OQS04127.1 - 2.1 8.4 30.6 0.31 11.1 26.2 1.7 2 0 0 2 2 2 0 YL1 nuclear protein BUD22 PF09073.10 OQS04127.1 - 5.1 6.3 22.5 8.3 5.6 22.5 1.3 1 0 0 1 1 1 0 BUD22 Nop14 PF04147.12 OQS04127.1 - 5.3 5.1 27.3 7.8 4.6 27.3 1.2 1 0 0 1 1 1 0 Nop14-like family UPF0086 PF01868.16 OQS04128.1 - 2.1e-13 50.0 0.0 3.1e-12 46.2 0.0 2.3 1 1 0 1 1 1 1 Domain of unknown function UPF0086 RL10P_insert PF17777.1 OQS04129.1 - 2.3e-24 85.2 0.0 4.3e-24 84.3 0.0 1.4 1 0 0 1 1 1 1 Insertion domain in 60S ribosomal protein L10P Ribosomal_L10 PF00466.20 OQS04129.1 - 1e-16 60.9 0.0 1.5e-16 60.3 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L10 JAB PF01398.21 OQS04131.1 - 3e-12 46.5 0.1 1e-11 44.8 0.1 1.8 1 1 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease GH115_C PF17829.1 OQS04131.1 - 0.042 13.7 0.0 0.089 12.6 0.0 1.5 1 0 0 1 1 1 0 Gylcosyl hydrolase family 115 C-terminal domain CRM1_C PF08767.11 OQS04132.1 - 8.2e-06 25.2 3.8 4.9e-05 22.6 3.8 2.5 1 0 0 1 1 1 1 CRM1 C terminal 5_nucleotid PF05761.14 OQS04133.1 - 6.1e-48 163.9 3.4 1.4e-47 162.6 3.4 1.5 1 1 0 1 1 1 1 5' nucleotidase family Glucan_synthase PF02364.15 OQS04134.1 - 1.8e-187 625.1 7.6 1.6e-165 552.5 3.6 2.5 1 1 1 2 2 2 2 1,3-beta-glucan synthase component FKS1_dom1 PF14288.6 OQS04134.1 - 6.5e-21 75.0 0.4 7.1e-19 68.4 0.4 3.0 1 1 0 1 1 1 1 1,3-beta-glucan synthase subunit FKS1, domain-1 PAP_central PF04928.17 OQS04135.1 - 9.1e-84 280.3 0.0 1.2e-83 279.9 0.0 1.2 1 0 0 1 1 1 1 Poly(A) polymerase central domain NTP_transf_2 PF01909.23 OQS04135.1 - 1.9e-06 28.1 0.0 3.4e-06 27.2 0.0 1.4 1 0 0 1 1 1 1 Nucleotidyltransferase domain DUF533 PF04391.12 OQS04136.1 - 0.09 12.3 0.2 0.091 12.3 0.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF533) RINT1_TIP1 PF04437.13 OQS04137.1 - 2.1e-73 247.9 0.5 2.1e-73 247.9 0.5 2.8 2 1 0 2 2 2 1 RINT-1 / TIP-1 family FAM184 PF15665.5 OQS04137.1 - 0.24 11.2 6.8 0.36 10.6 5.8 1.9 2 0 0 2 2 2 0 Family with sequence similarity 184, A and B zf-MYND PF01753.18 OQS04138.1 - 0.0003 20.8 11.1 0.0003 20.8 11.1 2.3 2 0 0 2 2 2 1 MYND finger PhetRS_B1 PF18262.1 OQS04138.1 - 0.032 14.4 0.0 0.076 13.2 0.0 1.5 1 0 0 1 1 1 0 Phe-tRNA synthetase beta subunit B1 domain RrnaAD PF00398.20 OQS04138.1 - 0.15 11.1 0.0 1 8.3 0.0 2.0 2 0 0 2 2 2 0 Ribosomal RNA adenine dimethylase Tail_VII PF17091.5 OQS04138.1 - 1.9 8.5 4.1 0.65 9.9 0.7 1.9 2 0 0 2 2 2 0 Inovirus G7P protein CENP-F_leu_zip PF10473.9 OQS04139.1 - 9e-05 22.5 20.2 9e-05 22.5 20.2 2.6 1 1 1 2 2 2 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 KxDL PF10241.9 OQS04139.1 - 0.00035 20.8 3.5 0.00035 20.8 3.5 3.1 2 1 0 3 3 2 1 Uncharacterized conserved protein CALCOCO1 PF07888.11 OQS04139.1 - 0.00037 19.5 27.7 0.00048 19.1 27.7 1.1 1 0 0 1 1 1 1 Calcium binding and coiled-coil domain (CALCOCO1) like JIP_LZII PF16471.5 OQS04139.1 - 0.00045 20.3 7.7 0.00045 20.3 7.7 4.6 2 1 3 5 5 4 1 JNK-interacting protein leucine zipper II DUF4795 PF16043.5 OQS04139.1 - 0.00048 19.8 6.6 0.00048 19.8 6.6 2.5 1 1 1 2 2 2 1 Domain of unknown function (DUF4795) KASH_CCD PF14662.6 OQS04139.1 - 0.0027 17.5 10.2 0.0027 17.5 10.2 3.2 1 1 2 3 3 3 1 Coiled-coil region of CCDC155 or KASH HAP1_N PF04849.13 OQS04139.1 - 0.0041 16.4 24.6 0.0041 16.4 24.6 2.1 1 1 1 2 2 2 1 HAP1 N-terminal conserved region Spc7 PF08317.11 OQS04139.1 - 0.0042 16.0 10.5 0.0042 16.0 10.5 2.2 1 1 1 2 2 2 1 Spc7 kinetochore protein FliJ PF02050.16 OQS04139.1 - 0.0057 16.9 6.0 0.0057 16.9 6.0 2.7 1 1 1 2 2 2 1 Flagellar FliJ protein Fez1 PF06818.15 OQS04139.1 - 0.0057 17.1 26.1 0.051 14.0 22.6 2.2 1 1 1 2 2 2 1 Fez1 HALZ PF02183.18 OQS04139.1 - 0.0069 16.6 20.1 0.12 12.6 0.1 4.6 4 0 0 4 4 4 2 Homeobox associated leucine zipper USP8_interact PF08941.10 OQS04139.1 - 0.0071 16.2 9.2 0.59 9.9 3.3 2.8 2 1 0 2 2 2 2 USP8 interacting ADIP PF11559.8 OQS04139.1 - 0.011 15.9 29.9 1.2 9.2 16.5 2.6 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding DUF4200 PF13863.6 OQS04139.1 - 0.015 15.7 13.9 0.015 15.7 13.9 3.0 1 1 2 3 3 3 0 Domain of unknown function (DUF4200) LPP PF04728.13 OQS04139.1 - 0.018 15.4 5.3 0.24 11.8 0.1 3.5 1 1 2 3 3 3 0 Lipoprotein leucine-zipper ZapB PF06005.12 OQS04139.1 - 0.019 15.4 2.7 0.019 15.4 2.7 4.7 1 1 2 3 3 3 0 Cell division protein ZapB Macoilin PF09726.9 OQS04139.1 - 0.047 12.3 27.6 0.046 12.3 18.1 2.0 1 1 1 2 2 2 0 Macoilin family YabA PF06156.13 OQS04139.1 - 0.054 14.1 29.0 0.98 10.1 6.1 4.1 1 1 3 4 4 4 0 Initiation control protein YabA DASH_Duo1 PF08651.10 OQS04139.1 - 0.054 13.3 13.0 1.4 8.7 1.2 4.4 4 0 0 4 4 4 0 DASH complex subunit Duo1 HLH PF00010.26 OQS04139.1 - 0.06 13.3 0.5 0.27 11.2 0.2 2.3 2 0 0 2 2 1 0 Helix-loop-helix DNA-binding domain EloA-BP1 PF15870.5 OQS04139.1 - 0.061 13.6 9.1 0.023 15.0 6.4 1.7 2 0 0 2 2 1 0 ElonginA binding-protein 1 DUF1664 PF07889.12 OQS04139.1 - 0.068 13.2 11.2 0.028 14.5 4.3 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) GAS PF13851.6 OQS04139.1 - 0.082 12.2 31.0 0.3 10.4 19.7 2.2 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Prefoldin PF02996.17 OQS04139.1 - 0.096 12.6 13.4 0.93 9.4 0.2 3.7 1 1 1 3 3 3 0 Prefoldin subunit Lebercilin PF15619.6 OQS04139.1 - 0.12 12.0 34.7 0.33 10.6 30.6 2.7 2 1 1 3 3 3 0 Ciliary protein causing Leber congenital amaurosis disease Fmp27_WPPW PF10359.9 OQS04139.1 - 0.16 10.8 23.3 0.037 12.9 18.4 1.9 1 1 1 2 2 2 0 RNA pol II promoter Fmp27 protein domain CLZ PF16526.5 OQS04139.1 - 0.16 12.3 23.8 0.22 11.9 4.8 4.9 1 1 4 5 5 5 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Phage_GP20 PF06810.11 OQS04139.1 - 0.19 11.6 26.3 1.2 8.9 4.9 2.8 1 1 2 3 3 3 0 Phage minor structural protein GP20 ABC_tran_CTD PF16326.5 OQS04139.1 - 0.19 12.0 19.9 0.11 12.8 4.6 3.9 1 1 1 2 2 2 0 ABC transporter C-terminal domain HOOK PF05622.12 OQS04139.1 - 0.23 9.6 30.8 0.04 12.1 18.8 2.0 1 1 1 2 2 2 0 HOOK protein NPV_P10 PF05531.12 OQS04139.1 - 0.3 11.6 12.5 7.7 7.1 2.6 3.6 1 1 2 3 3 3 0 Nucleopolyhedrovirus P10 protein MCC-bdg_PDZ PF10506.9 OQS04139.1 - 0.33 11.0 17.2 0.24 11.4 1.9 5.0 4 2 1 5 5 4 0 PDZ domain of MCC-2 bdg protein for Usher syndrome DUF1515 PF07439.11 OQS04139.1 - 0.34 10.9 9.2 2.3 8.3 0.0 3.3 2 1 1 3 3 3 0 Protein of unknown function (DUF1515) DUF1192 PF06698.11 OQS04139.1 - 0.36 10.9 5.9 0.58 10.3 1.9 2.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1192) GIT_CC PF16559.5 OQS04139.1 - 0.49 10.3 19.9 2.1 8.3 0.9 4.4 2 1 1 4 4 3 0 GIT coiled-coil Rho guanine nucleotide exchange factor THOC7 PF05615.13 OQS04139.1 - 0.5 10.7 20.9 1.5 9.1 18.7 2.8 1 1 1 2 2 1 0 Tho complex subunit 7 bZIP_1 PF00170.21 OQS04139.1 - 0.51 10.5 25.6 0.075 13.1 3.6 5.2 3 2 1 4 4 4 0 bZIP transcription factor DUF2312 PF10073.9 OQS04139.1 - 0.63 9.7 9.0 0.29 10.8 3.0 2.7 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2312) ERM PF00769.19 OQS04139.1 - 0.68 9.7 31.0 1.1 9.1 31.0 1.4 1 0 0 1 1 1 0 Ezrin/radixin/moesin family TraF_2 PF13729.6 OQS04139.1 - 1.1 8.5 5.4 2.1 7.6 3.3 2.1 1 1 1 2 2 2 0 F plasmid transfer operon, TraF, protein FlaC_arch PF05377.11 OQS04139.1 - 1.2 9.5 20.1 3.5 8.1 0.8 5.3 3 1 3 6 6 4 0 Flagella accessory protein C (FlaC) DUF724 PF05266.14 OQS04139.1 - 1.3 8.8 23.3 0.022 14.6 11.7 2.7 1 1 2 3 3 3 0 Protein of unknown function (DUF724) GCN5L1 PF06320.13 OQS04139.1 - 1.4 9.1 18.6 1.4 9.1 1.8 3.7 1 1 2 3 3 3 0 GCN5-like protein 1 (GCN5L1) Sec34 PF04136.15 OQS04139.1 - 1.5 8.7 19.5 0.89 9.4 3.3 2.9 1 1 2 3 3 3 0 Sec34-like family zf-ZPR1 PF03367.13 OQS04139.1 - 1.7 8.5 10.6 0.26 11.1 4.5 2.5 1 1 2 3 3 3 0 ZPR1 zinc-finger domain APG6_N PF17675.1 OQS04139.1 - 2 8.9 35.5 0.73 10.4 23.3 3.1 1 1 2 3 3 3 0 Apg6 coiled-coil region TSC22 PF01166.18 OQS04139.1 - 2.7 8.4 30.1 0.55 10.6 1.3 5.7 2 1 3 6 6 6 0 TSC-22/dip/bun family ATG16 PF08614.11 OQS04139.1 - 3.2 8.0 34.4 0.066 13.4 16.4 2.6 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) DivIC PF04977.15 OQS04139.1 - 3.6 7.4 28.0 0.47 10.3 2.4 5.0 1 1 4 5 5 5 0 Septum formation initiator TFR_dimer PF04253.15 OQS04139.1 - 4.6 7.4 8.1 3.4 7.8 0.3 3.3 2 1 1 3 3 3 0 Transferrin receptor-like dimerisation domain Uso1_p115_C PF04871.13 OQS04139.1 - 4.6 7.6 31.8 0.21 11.9 12.8 3.4 1 1 2 3 3 3 0 Uso1 / p115 like vesicle tethering protein, C terminal region Laminin_II PF06009.12 OQS04139.1 - 4.8 7.2 19.6 0.12 12.3 8.3 3.1 1 1 2 3 3 3 0 Laminin Domain II UPF0184 PF03670.13 OQS04139.1 - 5 7.6 11.0 1.2 9.6 1.8 3.3 1 1 0 2 2 2 0 Uncharacterised protein family (UPF0184) TolA_bind_tri PF16331.5 OQS04139.1 - 6.2 7.0 19.0 0.53 10.4 3.6 4.1 1 1 3 4 4 4 0 TolA binding protein trimerisation XhlA PF10779.9 OQS04139.1 - 6.7 7.0 13.9 3 8.1 1.1 3.6 1 1 3 4 4 4 0 Haemolysin XhlA Vac_Fusion PF02346.16 OQS04139.1 - 7.7 6.2 8.6 2.2 8.0 2.1 2.9 2 1 0 2 2 2 0 Chordopoxvirus multifunctional envelope protein A27 Nas2_N PF18265.1 OQS04139.1 - 8.3 6.4 10.2 2.2 8.3 0.6 3.7 1 1 1 3 3 3 0 Nas2 N_terminal domain Abhydrolase_1 PF00561.20 OQS04140.1 - 1.7e-13 50.8 0.3 8.7e-07 28.8 0.1 2.2 1 1 1 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 OQS04140.1 - 1.7e-05 24.2 0.1 0.003 16.8 0.1 2.2 1 1 0 1 1 1 1 Serine aminopeptidase, S33 FSH1 PF03959.13 OQS04140.1 - 2.4e-05 24.1 0.0 0.00041 20.1 0.0 2.4 1 1 1 2 2 2 1 Serine hydrolase (FSH1) Abhydrolase_4 PF08386.10 OQS04140.1 - 0.00027 21.0 0.0 0.00055 20.0 0.0 1.5 1 0 0 1 1 1 1 TAP-like protein PhoPQ_related PF10142.9 OQS04140.1 - 0.037 12.7 0.0 0.17 10.6 0.0 1.8 2 0 0 2 2 2 0 PhoPQ-activated pathogenicity-related protein UCH PF00443.29 OQS04141.1 - 2.3e-75 253.4 0.1 3.3e-75 252.9 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 OQS04141.1 - 1.7e-12 47.6 2.2 1.3e-06 28.3 0.0 3.1 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase zf-FPG_IleRS PF06827.14 OQS04141.1 - 0.24 11.3 3.4 3.6 7.6 0.1 2.6 2 0 0 2 2 2 0 Zinc finger found in FPG and IleRS Cys_rich_KTR PF14205.6 OQS04141.1 - 0.39 10.5 1.3 2 8.3 0.2 2.4 2 0 0 2 2 2 0 Cysteine-rich KTR zf-ribbon_3 PF13248.6 OQS04141.1 - 0.65 9.5 2.0 27 4.3 0.2 2.5 2 0 0 2 2 2 0 zinc-ribbon domain zf_UBZ PF18439.1 OQS04141.1 - 2.1 8.0 7.5 5.6 6.6 0.2 3.3 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger Lipase_3 PF01764.25 OQS04142.1 - 2.2e-30 105.4 0.6 5.7e-30 104.0 0.1 1.9 2 0 0 2 2 2 1 Lipase (class 3) Hydrolase_4 PF12146.8 OQS04142.1 - 0.017 14.4 0.2 0.1 11.8 0.2 2.1 1 1 0 1 1 1 0 Serine aminopeptidase, S33 DUF2974 PF11187.8 OQS04142.1 - 0.031 13.8 0.1 0.28 10.7 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2974) Abhydrolase_6 PF12697.7 OQS04142.1 - 0.069 13.7 0.3 0.16 12.5 0.0 1.7 2 0 0 2 2 2 0 Alpha/beta hydrolase family NPCC PF08058.11 OQS04142.1 - 0.57 10.2 2.5 1.4 9.0 0.0 2.8 2 1 0 2 2 2 0 Nuclear pore complex component Mannosyl_trans3 PF11051.8 OQS04143.1 - 4.2e-71 239.5 0.1 9.4e-36 123.6 0.1 4.3 3 2 0 3 3 3 2 Mannosyltransferase putative Asp4 PF16996.5 OQS04143.1 - 0.13 12.0 6.6 0.16 11.8 0.6 2.5 2 0 0 2 2 2 0 Accessory secretory protein Sec Asp4 Pkinase PF00069.25 OQS04144.1 - 2.2e-69 233.7 0.0 3.8e-69 233.0 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQS04144.1 - 1.5e-33 116.2 0.0 2.7e-33 115.4 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase PH PF00169.29 OQS04144.1 - 2e-08 34.7 0.1 7.4e-08 32.8 0.0 2.0 2 0 0 2 2 1 1 PH domain zf-C2H2 PF00096.26 OQS04144.1 - 3.5e-06 27.2 11.5 0.0075 16.7 3.0 3.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type Haspin_kinase PF12330.8 OQS04144.1 - 4.2e-06 25.9 0.2 8.4e-06 25.0 0.2 1.4 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 OQS04144.1 - 5.9e-05 22.5 1.0 0.00013 21.4 1.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family PH_6 PF15406.6 OQS04144.1 - 0.00073 19.8 0.0 0.0021 18.4 0.0 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain zf-H2C2_2 PF13465.6 OQS04144.1 - 0.00087 19.6 14.1 0.0031 17.9 2.9 3.9 4 0 0 4 4 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 OQS04144.1 - 0.0022 18.7 10.9 0.076 13.9 2.0 3.5 3 0 0 3 3 3 2 C2H2-type zinc finger Kinase-like PF14531.6 OQS04144.1 - 0.0033 16.8 0.0 0.0075 15.6 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 OQS04144.1 - 0.0077 15.0 0.0 0.019 13.7 0.0 1.6 1 0 0 1 1 1 1 Fungal protein kinase C2 PF00168.30 OQS04144.1 - 0.012 15.8 0.0 1.1 9.5 0.0 3.1 3 0 0 3 3 3 0 C2 domain zf-C2H2_11 PF16622.5 OQS04144.1 - 0.031 14.0 1.3 0.13 12.1 0.2 2.5 2 0 0 2 2 2 0 zinc-finger C2H2-type PH_11 PF15413.6 OQS04144.1 - 0.035 14.5 0.0 0.3 11.5 0.0 2.5 1 1 0 1 1 1 0 Pleckstrin homology domain APH PF01636.23 OQS04144.1 - 0.39 10.6 2.6 3.8 7.4 0.0 2.8 2 1 1 3 3 3 0 Phosphotransferase enzyme family TPR_1 PF00515.28 OQS04145.1 - 1.9e-22 78.1 3.8 1.1e-08 34.6 0.0 3.6 4 0 0 4 4 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 OQS04145.1 - 3.6e-18 64.1 2.5 5.9e-06 26.0 0.0 3.8 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.6 OQS04145.1 - 5.4e-15 54.3 2.8 7.7e-06 25.7 0.1 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 OQS04145.1 - 1.2e-10 41.5 0.6 4.3e-06 26.9 0.4 3.1 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 OQS04145.1 - 4.8e-10 39.0 5.3 0.0028 17.3 0.2 3.7 2 1 1 3 3 3 3 TPR repeat TPR_17 PF13431.6 OQS04145.1 - 1.2e-09 37.9 3.1 1.4e-05 25.2 0.1 5.0 4 2 1 5 5 5 1 Tetratricopeptide repeat TPR_14 PF13428.6 OQS04145.1 - 3.3e-09 36.8 0.0 0.00062 20.4 0.0 3.1 2 1 1 3 3 2 2 Tetratricopeptide repeat TPR_7 PF13176.6 OQS04145.1 - 3.7e-09 36.0 0.1 0.014 15.4 0.0 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_19 PF14559.6 OQS04145.1 - 1.1e-08 35.4 1.0 2.4e-08 34.3 0.3 1.9 2 0 0 2 2 2 1 Tetratricopeptide repeat ANAPC3 PF12895.7 OQS04145.1 - 1.2e-07 31.9 3.0 2.5e-05 24.4 0.2 2.3 2 0 0 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 Fis1_TPR_C PF14853.6 OQS04145.1 - 1.3e-07 31.6 7.2 0.00085 19.3 0.1 3.0 3 0 0 3 3 3 2 Fis1 C-terminal tetratricopeptide repeat TPR_6 PF13174.6 OQS04145.1 - 7.3e-07 29.4 3.9 0.026 15.1 0.1 4.5 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_9 PF13371.6 OQS04145.1 - 1.3e-06 28.4 0.0 3.6e-06 27.0 0.0 1.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 OQS04145.1 - 3e-06 27.8 0.1 0.0011 19.5 0.0 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat NARP1 PF12569.8 OQS04145.1 - 4.6e-06 25.8 0.7 6.6e-06 25.3 0.4 1.4 1 1 0 1 1 1 1 NMDA receptor-regulated protein 1 TPR_20 PF14561.6 OQS04145.1 - 0.00034 20.9 0.4 0.0012 19.1 0.4 2.0 1 1 0 1 1 1 1 Tetratricopeptide repeat Alkyl_sulf_dimr PF14863.6 OQS04145.1 - 0.00069 20.1 0.9 0.013 16.0 0.9 2.3 1 1 0 1 1 1 1 Alkyl sulfatase dimerisation MIT PF04212.18 OQS04145.1 - 0.001 19.1 2.2 6.6 6.9 0.1 3.5 2 1 1 3 3 3 1 MIT (microtubule interacting and transport) domain DUF3856 PF12968.7 OQS04145.1 - 0.0014 18.7 0.8 0.059 13.4 0.2 2.8 2 1 0 2 2 2 1 Domain of Unknown Function (DUF3856) BTAD PF03704.17 OQS04145.1 - 0.002 18.6 0.2 0.0068 16.8 0.2 1.9 1 1 0 1 1 1 1 Bacterial transcriptional activator domain TPR_10 PF13374.6 OQS04145.1 - 0.0034 17.2 0.8 0.22 11.5 0.1 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat DUF5588 PF17826.1 OQS04145.1 - 0.0063 15.4 0.3 0.049 12.5 0.3 2.0 1 1 0 1 1 1 1 Family of unknown function (DUF5588) SRP_TPR_like PF17004.5 OQS04145.1 - 0.011 15.8 2.4 0.19 11.8 0.3 2.2 2 0 0 2 2 2 0 Putative TPR-like repeat DUF4919 PF16266.5 OQS04145.1 - 0.02 14.8 0.1 0.043 13.8 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4919) TPR_15 PF13429.6 OQS04145.1 - 0.058 12.6 1.3 0.3 10.3 0.1 2.3 2 1 1 3 3 3 0 Tetratricopeptide repeat ParD_antitoxin PF03693.14 OQS04145.1 - 0.094 13.1 0.0 0.19 12.1 0.0 1.5 1 1 0 1 1 1 0 Bacterial antitoxin of ParD toxin-antitoxin type II system and RHH TPR_1 PF00515.28 OQS04146.1 - 4.1e-14 51.7 7.3 1.3e-09 37.5 1.2 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 OQS04146.1 - 1.8e-12 46.4 4.7 1.7e-07 30.8 0.6 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.6 OQS04146.1 - 3e-10 39.5 4.7 5.6e-07 29.3 0.5 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 OQS04146.1 - 3.4e-09 37.1 3.2 1e-05 25.9 0.1 2.1 1 1 1 2 2 2 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 OQS04146.1 - 5.4e-07 29.6 1.0 0.00016 21.6 0.1 2.7 1 1 1 2 2 2 1 Fis1 C-terminal tetratricopeptide repeat TPR_14 PF13428.6 OQS04146.1 - 7.6e-07 29.4 0.0 0.0001 22.8 0.1 2.8 3 1 1 4 4 2 2 Tetratricopeptide repeat TPR_12 PF13424.6 OQS04146.1 - 2.8e-06 27.5 2.6 0.0001 22.5 2.4 2.4 2 1 0 2 2 2 1 Tetratricopeptide repeat ANAPC3 PF12895.7 OQS04146.1 - 7.7e-05 22.9 12.2 0.0026 18.0 4.5 2.5 1 1 2 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 OQS04146.1 - 9.1e-05 22.9 0.3 0.31 11.8 0.0 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.6 OQS04146.1 - 0.00027 20.6 6.1 0.0046 16.6 1.1 3.9 3 1 1 4 4 4 1 TPR repeat TPR_16 PF13432.6 OQS04146.1 - 0.0003 21.4 0.0 0.0036 17.9 0.0 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.6 OQS04146.1 - 0.00034 20.4 0.5 0.0016 18.3 0.0 2.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.6 OQS04146.1 - 0.0016 18.5 0.0 0.0064 16.6 0.0 1.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.6 OQS04146.1 - 0.0021 18.3 6.7 0.018 15.4 0.2 3.4 4 0 0 4 4 4 1 Tetratricopeptide repeat Sec8_exocyst PF04048.14 OQS04146.1 - 0.0063 16.4 0.3 0.013 15.4 0.2 1.6 1 1 0 1 1 1 1 Sec8 exocyst complex component specific domain MIT PF04212.18 OQS04146.1 - 0.0074 16.3 2.6 0.23 11.5 0.2 2.8 3 0 0 3 3 3 1 MIT (microtubule interacting and transport) domain TPR_10 PF13374.6 OQS04146.1 - 0.024 14.5 3.7 0.073 13.0 1.5 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat Metallophos PF00149.28 OQS04147.1 - 7.7e-13 49.4 1.4 7.7e-13 49.4 1.4 1.9 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase EF-hand_1 PF00036.32 OQS04147.1 - 1.8e-09 36.5 0.2 5.7e-07 28.6 0.1 3.0 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 OQS04147.1 - 3.4e-09 35.9 0.6 1.9e-05 24.2 0.2 3.4 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.6 OQS04147.1 - 1.9e-08 34.6 4.8 4.3e-05 23.9 0.9 3.7 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.6 OQS04147.1 - 0.00063 19.1 0.0 0.0027 17.1 0.0 2.1 1 0 0 1 1 1 1 EF hand EF-hand_8 PF13833.6 OQS04147.1 - 0.0015 18.3 0.1 0.0076 16.1 0.1 2.1 2 0 0 2 2 2 1 EF-hand domain pair SMC_N PF02463.19 OQS04148.1 - 8.7e-64 215.0 0.5 1.9e-63 213.9 0.5 1.8 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 OQS04148.1 - 1.9e-25 89.4 0.0 6.7e-25 87.7 0.0 2.0 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain DUF726 PF05277.12 OQS04148.1 - 3.5e-15 55.8 0.4 2e-14 53.3 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF726) AAA_21 PF13304.6 OQS04148.1 - 2.1e-12 47.4 15.6 2.5e-08 34.1 1.9 4.9 2 2 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 OQS04148.1 - 3.2e-12 47.4 17.1 3.2e-12 47.4 17.1 7.0 2 2 2 5 5 2 1 AAA domain AAA_15 PF13175.6 OQS04148.1 - 2e-10 40.9 14.9 2e-10 40.9 14.9 4.0 2 2 1 3 3 2 1 AAA ATPase domain AAA_29 PF13555.6 OQS04148.1 - 2.2e-07 30.5 0.0 5.8e-07 29.2 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain Lipase_3 PF01764.25 OQS04148.1 - 3.6e-05 23.7 0.9 0.00044 20.1 0.0 3.1 3 0 0 3 3 3 1 Lipase (class 3) DUF676 PF05057.14 OQS04148.1 - 0.0063 16.0 0.0 0.029 13.9 0.0 2.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Fez1 PF06818.15 OQS04148.1 - 0.011 16.3 13.4 0.011 16.3 13.4 7.1 2 2 4 6 6 3 0 Fez1 SbcCD_C PF13558.6 OQS04148.1 - 0.039 14.2 0.0 0.16 12.2 0.0 2.1 2 0 0 2 2 1 0 Putative exonuclease SbcCD, C subunit LIDHydrolase PF10230.9 OQS04148.1 - 0.14 11.7 4.5 3.8 7.0 0.0 3.4 2 1 1 3 3 3 0 Lipid-droplet associated hydrolase Abhydrolase_1 PF00561.20 OQS04148.1 - 0.15 11.7 0.0 0.52 9.9 0.0 1.9 1 0 0 1 1 1 0 alpha/beta hydrolase fold PASTA PF03793.19 OQS04148.1 - 0.15 11.9 0.1 1.1 9.1 0.0 2.5 2 0 0 2 2 2 0 PASTA domain AAA_22 PF13401.6 OQS04148.1 - 3.7 7.8 6.5 22 5.3 0.0 4.4 4 1 0 4 4 3 0 AAA domain YjbF PF11102.8 OQS04149.1 - 0.13 12.0 0.1 0.22 11.3 0.1 1.3 1 0 0 1 1 1 0 Group 4 capsule polysaccharide lipoprotein gfcB, YjbF Fis1_TPR_C PF14853.6 OQS04150.1 - 5.2e-05 23.2 0.5 0.0018 18.3 0.1 2.7 2 1 0 2 2 2 1 Fis1 C-terminal tetratricopeptide repeat TPR_1 PF00515.28 OQS04150.1 - 0.0045 16.8 0.1 0.024 14.5 0.0 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.17 OQS04150.1 - 0.02 15.0 0.0 0.069 13.3 0.0 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_8 PF13181.6 OQS04150.1 - 0.041 14.1 0.1 0.2 11.9 0.1 2.2 1 0 0 1 1 1 0 Tetratricopeptide repeat p450 PF00067.22 OQS04150.1 - 0.064 12.0 0.3 0.079 11.7 0.3 1.1 1 0 0 1 1 1 0 Cytochrome P450 TPR_1 PF00515.28 OQS04151.1 - 8.4e-06 25.4 0.4 1.2e-05 24.9 0.4 1.2 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_8 PF13181.6 OQS04151.1 - 0.00021 21.3 0.4 0.00032 20.7 0.4 1.3 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_2 PF07719.17 OQS04151.1 - 0.0062 16.6 0.3 0.0085 16.1 0.3 1.2 1 0 0 1 1 1 1 Tetratricopeptide repeat RE_BstXI PF09552.10 OQS04151.1 - 0.03 13.5 0.0 0.031 13.5 0.0 1.0 1 0 0 1 1 1 0 BstXI restriction endonuclease DUF572 PF04502.13 OQS04152.1 - 1.7e-76 258.0 18.6 6.4e-76 256.1 18.5 1.7 1 1 0 1 1 1 1 Family of unknown function (DUF572) zf-FCS PF06467.14 OQS04152.1 - 0.35 10.8 2.0 20 5.2 0.1 2.5 2 0 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif DUF4505 PF14956.6 OQS04153.1 - 1.3e-34 119.5 1.0 1.9e-34 119.0 1.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4505) DUF5074 PF16819.5 OQS04153.1 - 0.13 12.3 0.4 0.28 11.2 0.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF5074) Thioredoxin PF00085.20 OQS04154.1 - 1e-23 83.2 0.0 1.2e-23 83.1 0.0 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 OQS04154.1 - 3.1e-06 27.6 0.3 2.7e-05 24.6 0.3 2.0 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 OQS04154.1 - 1.1e-05 25.7 0.0 1.5e-05 25.2 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like Glutaredoxin PF00462.24 OQS04154.1 - 0.00057 20.1 0.0 0.0011 19.2 0.0 1.4 1 0 0 1 1 1 1 Glutaredoxin Thioredoxin_9 PF14595.6 OQS04154.1 - 0.0024 17.6 0.0 0.0027 17.5 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_7 PF13899.6 OQS04154.1 - 0.015 15.4 0.1 0.026 14.7 0.1 1.4 1 1 0 1 1 1 0 Thioredoxin-like AhpC-TSA PF00578.21 OQS04154.1 - 0.034 14.1 0.0 0.038 13.9 0.0 1.3 1 0 0 1 1 1 0 AhpC/TSA family OST3_OST6 PF04756.13 OQS04154.1 - 0.041 13.2 0.0 0.047 13.0 0.0 1.2 1 0 0 1 1 1 0 OST3 / OST6 family, transporter family Cu-oxidase_2 PF07731.14 OQS04155.1 - 1.9e-11 43.8 9.7 2.3e-10 40.4 10.2 2.4 1 1 1 2 2 2 1 Multicopper oxidase Cu-oxidase PF00394.22 OQS04155.1 - 0.038 14.1 0.0 0.17 12.0 0.0 1.9 2 0 0 2 2 2 0 Multicopper oxidase Cu-oxidase_3 PF07732.15 OQS04156.1 - 3.5e-05 23.8 0.0 5.1e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 Multicopper oxidase Ribonuc_L-PSP PF01042.21 OQS04157.1 - 8.1e-08 32.3 0.0 9.9e-08 32.0 0.0 1.2 1 0 0 1 1 1 1 Endoribonuclease L-PSP Thioredoxin PF00085.20 OQS04158.1 - 4.1e-22 78.1 0.0 5e-22 77.8 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin OST3_OST6 PF04756.13 OQS04158.1 - 9e-06 25.2 0.1 1.1e-05 25.0 0.1 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_2 PF13098.6 OQS04158.1 - 3.5e-05 24.2 0.2 0.00019 21.9 0.2 1.9 1 1 0 1 1 1 1 Thioredoxin-like domain DIM1 PF02966.16 OQS04158.1 - 0.00015 21.6 0.0 0.00019 21.2 0.0 1.1 1 0 0 1 1 1 1 Mitosis protein DIM1 Thioredoxin_8 PF13905.6 OQS04158.1 - 0.00023 21.5 0.1 0.00091 19.5 0.0 1.9 1 1 1 2 2 2 1 Thioredoxin-like TraF PF13728.6 OQS04158.1 - 0.0003 20.7 0.0 0.00032 20.6 0.0 1.1 1 0 0 1 1 1 1 F plasmid transfer operon protein Redoxin PF08534.10 OQS04158.1 - 0.00095 18.9 0.0 0.0012 18.6 0.0 1.1 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 OQS04158.1 - 0.001 19.0 0.0 0.0013 18.6 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Glutaredoxin PF00462.24 OQS04158.1 - 0.0012 19.0 0.0 0.0024 18.0 0.0 1.4 1 0 0 1 1 1 1 Glutaredoxin Thioredoxin_7 PF13899.6 OQS04158.1 - 0.0013 18.9 0.1 0.0018 18.4 0.1 1.3 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_6 PF13848.6 OQS04158.1 - 0.011 15.7 0.1 0.013 15.4 0.1 1.1 1 0 0 1 1 1 0 Thioredoxin-like domain Thioredoxin_9 PF14595.6 OQS04158.1 - 0.016 15.0 0.0 0.018 14.8 0.0 1.1 1 0 0 1 1 1 0 Thioredoxin T4_deiodinase PF00837.17 OQS04158.1 - 0.12 11.7 0.0 0.13 11.5 0.0 1.1 1 0 0 1 1 1 0 Iodothyronine deiodinase Thioredoxin PF00085.20 OQS04159.1 - 4.1e-25 87.7 0.1 4.7e-25 87.6 0.1 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_7 PF13899.6 OQS04159.1 - 1.2e-06 28.6 0.0 1.7e-06 28.1 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.6 OQS04159.1 - 6.1e-06 26.6 0.1 7.5e-05 23.1 0.1 2.0 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 OQS04159.1 - 7.1e-05 23.1 0.0 0.00012 22.3 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like AhpC-TSA PF00578.21 OQS04159.1 - 0.00042 20.2 0.1 0.00051 20.0 0.1 1.3 1 1 0 1 1 1 1 AhpC/TSA family Thioredoxin_9 PF14595.6 OQS04159.1 - 0.00072 19.3 0.0 0.00086 19.1 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Glutaredoxin PF00462.24 OQS04159.1 - 0.0014 18.8 0.1 0.0025 18.0 0.1 1.3 1 0 0 1 1 1 1 Glutaredoxin OST3_OST6 PF04756.13 OQS04159.1 - 0.0022 17.4 0.1 0.0026 17.1 0.1 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Redoxin PF08534.10 OQS04159.1 - 0.0025 17.5 0.1 0.0047 16.6 0.1 1.6 1 1 1 2 2 2 1 Redoxin DUF953 PF06110.11 OQS04159.1 - 0.14 11.8 0.1 0.56 9.8 0.1 2.0 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF953) Aminotran_3 PF00202.21 OQS04160.1 - 1.1e-109 366.8 0.0 1.3e-109 366.6 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Methyltransf_16 PF10294.9 OQS04161.1 - 4.7e-33 114.4 0.1 6.3e-33 113.9 0.1 1.2 1 0 0 1 1 1 1 Lysine methyltransferase PrmA PF06325.13 OQS04161.1 - 0.00041 19.8 0.0 0.00058 19.3 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 OQS04161.1 - 0.019 14.5 0.0 0.036 13.6 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Cons_hypoth95 PF03602.15 OQS04161.1 - 0.074 12.7 0.1 0.18 11.5 0.0 1.6 2 0 0 2 2 2 0 Conserved hypothetical protein 95 Ion_trans PF00520.31 OQS04162.1 - 5.2e-40 137.2 33.9 1.1e-22 80.5 14.3 2.5 3 0 0 3 3 3 2 Ion transport protein Ion_trans_2 PF07885.16 OQS04162.1 - 1.4e-23 82.6 26.1 2.7e-14 52.9 1.7 3.6 3 0 0 3 3 3 2 Ion channel ABC_tran PF00005.27 OQS04163.1 - 5.3e-47 159.8 0.0 2.2e-27 96.3 0.0 2.4 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 OQS04163.1 - 4.1e-40 138.2 37.3 1.9e-21 76.9 10.8 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.19 OQS04163.1 - 3.6e-06 26.6 1.7 0.024 14.1 0.0 3.7 3 1 1 4 4 4 1 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 OQS04163.1 - 7.5e-06 26.0 0.2 0.024 14.7 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 OQS04163.1 - 0.00032 20.6 1.0 0.37 10.7 0.1 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_16 PF13191.6 OQS04163.1 - 0.00054 20.4 0.0 0.54 10.6 0.0 2.8 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.6 OQS04163.1 - 0.0043 16.8 0.2 2.9 7.7 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_21 PF13304.6 OQS04163.1 - 0.0071 16.2 0.0 6.2 6.5 0.2 3.3 2 1 1 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system DUF815 PF05673.13 OQS04163.1 - 0.0072 15.5 0.5 2.2 7.4 0.1 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF815) IstB_IS21 PF01695.17 OQS04163.1 - 0.049 13.4 1.7 4.5 7.0 0.0 2.9 3 0 0 3 3 3 0 IstB-like ATP binding protein RNA_helicase PF00910.22 OQS04163.1 - 0.099 13.0 0.1 12 6.3 0.0 2.7 2 0 0 2 2 2 0 RNA helicase AAA_7 PF12775.7 OQS04163.1 - 0.12 11.8 0.1 7 6.1 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region Dynamin_N PF00350.23 OQS04163.1 - 0.17 11.9 4.3 3.7 7.6 0.6 2.4 2 0 0 2 2 2 0 Dynamin family AAA_22 PF13401.6 OQS04163.1 - 0.23 11.7 2.7 13 6.1 0.1 2.9 2 1 0 2 2 2 0 AAA domain AAA_23 PF13476.6 OQS04163.1 - 0.25 11.8 0.9 4.3 7.8 0.1 2.2 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.17 OQS04163.1 - 0.37 10.8 2.1 0.71 9.9 0.1 2.1 2 0 0 2 2 2 0 Helicase HerA, central domain PDCD2_C PF04194.13 OQS04165.1 - 4.7e-34 118.0 3.0 8.7e-34 117.1 0.3 2.3 3 0 0 3 3 3 1 Programmed cell death protein 2, C-terminal putative domain PDZ_6 PF17820.1 OQS04166.1 - 1.5e-10 40.8 0.0 0.003 17.4 0.0 3.7 4 0 0 4 4 4 3 PDZ domain PDZ PF00595.24 OQS04166.1 - 3e-09 37.1 0.2 0.0019 18.5 0.0 2.9 3 0 0 3 3 3 2 PDZ domain PDZ_2 PF13180.6 OQS04166.1 - 0.00021 21.5 0.0 0.53 10.6 0.0 2.8 3 0 0 3 3 3 2 PDZ domain GCV_H PF01597.19 OQS04167.1 - 4.5e-07 29.8 0.0 8.7e-07 28.9 0.0 1.6 1 1 0 1 1 1 1 Glycine cleavage H-protein zf-CCCH PF00642.24 OQS04167.1 - 0.012 15.5 1.5 0.012 15.5 1.5 1.7 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Csm1 PF12539.8 OQS04168.1 - 0.00011 22.8 0.1 0.00041 20.9 0.1 2.0 2 0 0 2 2 2 1 Chromosome segregation protein Csm1/Pcs1 Lzipper-MIP1 PF14389.6 OQS04168.1 - 0.016 15.5 1.5 0.016 15.5 1.5 2.6 1 1 1 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 Prp19 PF08606.11 OQS04168.1 - 0.043 13.8 2.7 0.089 12.8 0.4 2.4 2 0 0 2 2 2 0 Prp19/Pso4-like DUF2674 PF10879.8 OQS04168.1 - 0.12 12.0 5.2 0.17 11.4 2.9 2.4 1 1 2 3 3 3 0 Protein of unknown function (DUF2674) AAA_23 PF13476.6 OQS04168.1 - 0.19 12.2 13.8 0.41 11.1 13.8 1.5 1 0 0 1 1 1 0 AAA domain HTH_WhiA PF02650.14 OQS04168.1 - 0.27 11.6 8.2 2.6 8.5 1.8 2.7 1 1 1 2 2 2 0 WhiA C-terminal HTH domain TolA_bind_tri PF16331.5 OQS04168.1 - 0.27 11.3 9.5 0.8 9.8 5.4 2.7 1 1 1 2 2 2 0 TolA binding protein trimerisation TPR_8 PF13181.6 OQS04168.1 - 0.31 11.4 5.9 0.34 11.2 0.6 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat Cep57_CLD_2 PF14197.6 OQS04168.1 - 0.8 9.8 14.1 0.37 10.9 9.3 2.7 1 1 2 3 3 3 0 Centrosome localisation domain of PPC89 Cnn_1N PF07989.11 OQS04168.1 - 0.82 9.9 14.4 0.83 9.9 0.7 3.2 2 2 0 2 2 2 0 Centrosomin N-terminal motif 1 DUF4407 PF14362.6 OQS04168.1 - 2.4 7.5 8.6 3 7.1 8.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Ntox1 PF15500.6 OQS04168.1 - 2.4 8.6 7.8 0.41 11.0 1.9 2.5 1 1 1 2 2 2 0 Putative RNase-like toxin, toxin_1 CBP4 PF07960.11 OQS04168.1 - 2.5 8.0 12.2 1.5 8.7 9.9 1.9 1 1 0 1 1 1 0 CBP4 Exonuc_VII_L PF02601.15 OQS04168.1 - 3.6 7.1 10.9 5 6.6 10.9 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit FlxA PF14282.6 OQS04168.1 - 4.2 7.4 13.3 2.5 8.2 10.4 2.1 1 1 1 2 2 2 0 FlxA-like protein Peptidase_S46 PF10459.9 OQS04168.1 - 7.3 5.1 15.5 8.1 4.9 15.0 1.4 1 1 0 1 1 1 0 Peptidase S46 Mlh1_C PF16413.5 OQS04169.1 - 8.1e-66 222.1 0.1 8.7e-65 218.8 0.1 2.2 1 1 0 1 1 1 1 DNA mismatch repair protein Mlh1 C-terminus DNA_mis_repair PF01119.19 OQS04169.1 - 1.5e-33 115.0 0.3 3.5e-33 113.8 0.3 1.7 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.6 OQS04169.1 - 1.5e-12 47.6 0.0 3.5e-12 46.3 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 OQS04169.1 - 1.8e-06 28.4 0.0 4.5e-06 27.1 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase BCIP PF13862.6 OQS04169.1 - 0.045 13.5 0.2 0.49 10.1 0.1 2.5 2 0 0 2 2 2 0 p21-C-terminal region-binding protein NAD_Gly3P_dh_N PF01210.23 OQS04169.1 - 0.088 12.8 0.0 0.17 11.8 0.0 1.5 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus MutL_C PF08676.11 OQS04169.1 - 0.16 11.7 0.8 1.2 8.9 0.2 2.5 3 0 0 3 3 3 0 MutL C terminal dimerisation domain EamA PF00892.20 OQS04170.1 - 1e-05 25.8 14.4 1e-05 25.8 14.4 2.5 2 1 0 2 2 2 2 EamA-like transporter family TPT PF03151.16 OQS04170.1 - 0.01 15.2 15.5 0.018 14.4 15.5 1.4 1 1 0 1 1 1 0 Triose-phosphate Transporter family SKG6 PF08693.10 OQS04171.1 - 0.054 12.9 0.3 0.09 12.2 0.3 1.3 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Colicin PF01024.19 OQS04171.1 - 0.062 13.2 0.0 0.064 13.1 0.0 1.0 1 0 0 1 1 1 0 Colicin pore forming domain Blo-t-5 PF11642.8 OQS04172.1 - 0.22 11.5 0.0 0.33 10.9 0.0 1.2 1 0 0 1 1 1 0 Mite allergen Blo t 5 Myb_DNA-bind_6 PF13921.6 OQS04173.1 - 0.065 13.5 0.1 0.17 12.2 0.0 1.7 2 0 0 2 2 2 0 Myb-like DNA-binding domain CLLAC PF15675.5 OQS04174.1 - 0.018 14.6 0.5 0.034 13.7 0.5 1.5 1 0 0 1 1 1 0 CLLAC-motif containing domain JIP_LZII PF16471.5 OQS04176.1 - 0.038 14.1 0.4 0.038 14.1 0.4 3.3 3 0 0 3 3 3 0 JNK-interacting protein leucine zipper II DUF5082 PF16888.5 OQS04176.1 - 0.074 13.3 6.4 3.3 8.0 0.6 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF5082) Syntaxin-6_N PF09177.11 OQS04176.1 - 0.097 13.2 5.9 4.1 8.0 0.0 3.4 3 1 0 3 3 2 0 Syntaxin 6, N-terminal Prefoldin_2 PF01920.20 OQS04176.1 - 0.3 11.0 11.6 3.1 7.8 1.4 3.0 2 1 0 2 2 2 0 Prefoldin subunit Exonuc_VII_L PF02601.15 OQS04176.1 - 0.34 10.5 9.2 2.1 7.8 0.2 2.3 2 0 0 2 2 2 0 Exonuclease VII, large subunit BLOC1_2 PF10046.9 OQS04176.1 - 0.42 10.9 7.1 0.84 10.0 0.7 3.9 3 1 1 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Tho2 PF11262.8 OQS04176.1 - 0.65 9.1 5.0 12 5.0 2.7 2.5 2 0 0 2 2 2 0 Transcription factor/nuclear export subunit protein 2 DUF4407 PF14362.6 OQS04176.1 - 0.82 9.0 11.3 2 7.7 0.8 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Spc24 PF08286.11 OQS04176.1 - 0.83 9.9 9.5 3.9 7.8 0.9 2.8 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 NPV_P10 PF05531.12 OQS04176.1 - 0.97 9.9 8.1 1.6 9.2 1.2 4.2 4 1 0 4 4 4 0 Nucleopolyhedrovirus P10 protein TMV_coat PF00721.21 OQS04176.1 - 0.99 9.2 4.9 8.3 6.2 0.0 3.1 3 0 0 3 3 3 0 Virus coat protein (TMV like) Nsp1_C PF05064.13 OQS04176.1 - 1.5 8.6 12.1 8.9 6.2 1.3 3.4 3 0 0 3 3 3 0 Nsp1-like C-terminal region DUF5320 PF17253.2 OQS04176.1 - 1.6 9.8 3.4 13 6.9 0.5 2.7 2 0 0 2 2 2 0 Family of unknown function (DUF5320) OmpH PF03938.14 OQS04176.1 - 2.4 8.5 17.0 0.5 10.7 3.1 3.2 3 0 0 3 3 3 0 Outer membrane protein (OmpH-like) DUF4061 PF13270.6 OQS04176.1 - 3.4 8.1 8.6 16 5.9 0.8 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4061) Cytochrom_B562 PF07361.11 OQS04176.1 - 3.7 8.3 9.9 1.8 9.2 5.2 2.9 2 0 0 2 2 2 0 Cytochrome b562 Cnn_1N PF07989.11 OQS04176.1 - 4.8 7.4 10.3 1.1 9.4 1.0 2.8 2 0 0 2 2 2 0 Centrosomin N-terminal motif 1 YabA PF06156.13 OQS04176.1 - 5.4 7.7 9.1 0.47 11.1 0.8 3.0 2 1 0 2 2 2 0 Initiation control protein YabA Jnk-SapK_ap_N PF09744.9 OQS04176.1 - 7.6 6.7 23.0 0.2 11.8 0.8 3.3 2 1 0 3 3 3 0 JNK_SAPK-associated protein-1 DUF16 PF01519.16 OQS04176.1 - 9.3 6.8 9.5 2.8 8.5 1.8 2.9 3 0 0 3 3 2 0 Protein of unknown function DUF16 MitMem_reg PF13012.6 OQS04177.1 - 9.9e-34 116.1 0.9 1.6e-33 115.5 0.9 1.3 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function JAB PF01398.21 OQS04177.1 - 6.8e-25 87.3 0.0 1.3e-24 86.5 0.0 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Rab5-bind PF09311.11 OQS04177.1 - 0.049 13.0 0.0 0.073 12.4 0.0 1.2 1 0 0 1 1 1 0 Rabaptin-like protein Methyltr_RsmB-F PF01189.17 OQS04178.1 - 6.2e-73 244.7 0.0 1.3e-72 243.7 0.0 1.6 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F Methyltr_RsmF_N PF17125.5 OQS04178.1 - 2.2e-08 34.5 0.0 7.1e-08 32.9 0.0 1.9 1 0 0 1 1 1 1 N-terminal domain of 16S rRNA methyltransferase RsmF Methyltransf_31 PF13847.6 OQS04178.1 - 1.4e-05 25.0 0.0 3.3e-05 23.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.19 OQS04178.1 - 3.9e-05 23.8 0.0 8.3e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_25 PF13649.6 OQS04178.1 - 0.00021 21.9 0.0 0.00054 20.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 OQS04178.1 - 0.0013 18.5 0.0 0.0024 17.7 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Ubie_methyltran PF01209.18 OQS04178.1 - 0.002 17.5 0.0 0.0038 16.6 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_4 PF02390.17 OQS04178.1 - 0.15 11.5 0.0 0.15 11.5 0.0 3.1 3 0 0 3 3 3 0 Putative methyltransferase AAA_22 PF13401.6 OQS04179.1 - 2.7e-08 34.2 0.0 8.9e-07 29.3 0.0 3.0 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 OQS04179.1 - 3.5e-07 30.3 0.0 8.5e-07 29.0 0.0 1.7 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 OQS04179.1 - 9.8e-07 29.3 0.0 6.5e-06 26.6 0.0 2.4 1 0 0 1 1 1 1 AAA ATPase domain ATPase_2 PF01637.18 OQS04179.1 - 0.00014 21.8 0.6 0.0046 16.9 0.0 2.8 2 1 0 2 2 2 1 ATPase domain predominantly from Archaea Polysacc_deac_1 PF01522.21 OQS04179.1 - 0.012 15.5 0.8 6.9 6.6 0.0 3.2 3 0 0 3 3 3 0 Polysaccharide deacetylase Plasmid_RAQPRD PF09686.10 OQS04179.1 - 0.16 12.2 3.3 1 9.6 0.4 3.1 2 0 0 2 2 2 0 Plasmid protein of unknown function (Plasmid_RAQPRD) DUF948 PF06103.11 OQS04179.1 - 2.9 8.2 6.2 18 5.7 2.2 3.5 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) DUF2533 PF10752.9 OQS04179.1 - 3.9 8.0 6.5 5.9 7.4 4.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2533) GlcNAc PF11397.8 OQS04180.1 - 2.4e-46 158.8 0.3 7.5e-43 147.3 0.3 2.1 1 1 0 1 1 1 1 Glycosyltransferase (GlcNAc) RIC1 PF07064.13 OQS04182.1 - 9.1e-12 44.9 0.1 2.1e-11 43.7 0.1 1.6 1 0 0 1 1 1 1 RIC1 ACBP PF00887.19 OQS04182.1 - 4.2e-11 42.9 0.2 1.9e-10 40.8 0.0 2.1 2 0 0 2 2 2 1 Acyl CoA binding protein PDZ_6 PF17820.1 OQS04182.1 - 8e-10 38.4 0.1 1.9e-09 37.3 0.1 1.7 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 OQS04182.1 - 2.7e-07 30.9 0.0 4.9e-07 30.0 0.0 1.4 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 OQS04182.1 - 0.017 15.4 0.0 0.037 14.3 0.0 1.5 1 0 0 1 1 1 0 PDZ domain WD40 PF00400.32 OQS04183.1 - 5.4e-34 115.7 7.8 7.2e-08 33.0 0.0 7.1 7 0 0 7 7 7 5 WD domain, G-beta repeat Prp19 PF08606.11 OQS04183.1 - 2.9e-29 100.9 2.6 4e-28 97.2 2.2 2.4 1 1 1 2 2 2 1 Prp19/Pso4-like ANAPC4_WD40 PF12894.7 OQS04183.1 - 8.5e-14 51.6 0.2 0.0044 17.3 0.0 5.5 1 1 4 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 OQS04183.1 - 3.2e-07 29.6 2.3 0.015 14.2 0.0 4.0 1 1 3 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein zf-Nse PF11789.8 OQS04183.1 - 0.00012 21.8 0.1 0.00021 21.0 0.1 1.4 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit U-box PF04564.15 OQS04183.1 - 0.00085 19.5 0.0 0.0019 18.3 0.0 1.6 1 0 0 1 1 1 1 U-box domain WD40_like PF17005.5 OQS04183.1 - 0.026 13.9 0.0 2.7 7.2 0.0 2.7 2 1 0 2 2 2 0 WD40-like domain Spc7 PF08317.11 OQS04183.1 - 0.055 12.4 3.4 0.08 11.8 3.4 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF2850 PF11012.8 OQS04183.1 - 0.089 13.1 0.0 0.37 11.1 0.0 2.1 2 0 0 2 2 1 0 Protein of unknown function (DUF2850) Fez1 PF06818.15 OQS04183.1 - 0.13 12.7 2.4 0.23 11.9 2.4 1.4 1 0 0 1 1 1 0 Fez1 CREPT PF16566.5 OQS04183.1 - 0.26 11.5 2.7 0.47 10.6 2.7 1.4 1 0 0 1 1 1 0 Cell-cycle alteration and expression-elevated protein in tumour CENP-H PF05837.12 OQS04183.1 - 0.86 10.0 4.5 1.6 9.2 4.5 1.4 1 0 0 1 1 1 0 Centromere protein H (CENP-H) TSNAXIP1_N PF15739.5 OQS04183.1 - 2 8.8 6.1 0.4 11.1 0.9 2.2 2 0 0 2 2 2 0 Translin-associated factor X-interacting N-terminus GAS PF13851.6 OQS04183.1 - 5.4 6.3 9.2 51 3.1 8.4 2.1 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Aconitase PF00330.20 OQS04184.1 - 7.6e-144 480.1 0.0 9.8e-144 479.8 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 OQS04184.1 - 2.3e-45 154.1 0.0 5.3e-45 152.9 0.0 1.6 1 0 0 1 1 1 1 Aconitase C-terminal domain DUF521 PF04412.13 OQS04184.1 - 0.11 11.2 0.0 0.18 10.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF521) DUF1344 PF07076.11 OQS04184.1 - 0.12 12.3 0.1 26 4.8 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1344) Presenilin PF01080.17 OQS04185.1 - 1.9e-112 376.0 5.6 5.2e-112 374.5 5.6 1.6 1 1 0 1 1 1 1 Presenilin Afaf PF15339.6 OQS04185.1 - 0.041 13.6 0.4 0.11 12.2 0.4 1.7 1 1 0 1 1 1 0 Acrosome formation-associated factor DUF2981 PF11200.8 OQS04185.1 - 3.5 7.3 5.4 0.35 10.6 0.5 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2981) TMEM107 PF14995.6 OQS04186.1 - 8.6e-13 48.8 3.2 9.4e-13 48.7 3.2 1.0 1 0 0 1 1 1 1 Transmembrane protein ELK PF03789.13 OQS04186.1 - 0.18 12.0 1.5 0.39 10.8 1.5 1.5 1 0 0 1 1 1 0 ELK domain NCU-G1 PF15065.6 OQS04187.1 - 0.018 14.1 5.3 0.031 13.3 5.3 1.4 1 0 0 1 1 1 0 Lysosomal transcription factor, NCU-G1 DUF3634 PF12321.8 OQS04187.1 - 0.08 13.3 0.2 0.63 10.5 0.2 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3634) HTH_WhiA PF02650.14 OQS04187.1 - 0.094 13.1 1.6 2.3 8.6 0.2 3.4 2 0 0 2 2 2 0 WhiA C-terminal HTH domain DUF1664 PF07889.12 OQS04187.1 - 0.19 11.8 27.9 0.19 11.8 1.4 5.5 2 1 3 6 6 6 0 Protein of unknown function (DUF1664) RasGAP_C PF03836.15 OQS04187.1 - 0.61 10.2 12.2 0.35 11.0 0.5 4.3 5 1 1 6 6 6 0 RasGAP C-terminus Spc7 PF08317.11 OQS04187.1 - 1.6 7.5 29.2 0.15 10.9 7.3 3.8 1 1 2 4 4 4 0 Spc7 kinetochore protein GTP-bdg_M PF16360.5 OQS04187.1 - 3.7 8.2 7.1 69 4.1 0.1 5.0 5 1 0 5 5 5 0 GTP-binding GTPase Middle Region NPV_P10 PF05531.12 OQS04187.1 - 3.9 8.0 33.0 0.097 13.1 1.6 6.2 5 2 1 6 6 6 0 Nucleopolyhedrovirus P10 protein Laminin_II PF06009.12 OQS04187.1 - 4.1 7.4 22.9 3.2 7.8 2.7 4.4 1 1 2 4 4 4 0 Laminin Domain II Zip PF02535.22 OQS04188.1 - 1e-29 103.9 22.1 1.4e-28 100.1 19.0 2.4 2 1 0 2 2 2 1 ZIP Zinc transporter DUF460 PF04312.13 OQS04188.1 - 0.1 12.3 0.4 0.21 11.3 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF460) GAPT PF11770.8 OQS04189.1 - 0.052 13.4 0.0 0.09 12.6 0.0 1.3 1 0 0 1 1 1 0 GRB2-binding adapter (GAPT) Phage_holin_2_3 PF16080.5 OQS04189.1 - 0.14 12.0 0.0 0.29 10.9 0.0 1.6 1 0 0 1 1 1 0 Bacteriophage holin family HP1 PRCC PF10253.9 OQS04189.1 - 0.23 12.2 7.7 0.3 11.9 7.7 1.4 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting Ndc1_Nup PF09531.10 OQS04189.1 - 0.52 8.9 6.5 0.6 8.7 6.5 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup KAR9 PF08580.10 OQS04189.1 - 3.9 5.9 13.9 4.8 5.6 13.9 1.0 1 0 0 1 1 1 0 Yeast cortical protein KAR9 DUF3283 PF11686.8 OQS04190.1 - 0.018 14.9 0.0 0.032 14.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3283) Syndecan PF01034.20 OQS04190.1 - 0.036 14.0 0.1 0.073 13.0 0.1 1.4 1 0 0 1 1 1 0 Syndecan domain Podoplanin PF05808.11 OQS04190.1 - 0.068 13.3 0.0 0.1 12.7 0.0 1.3 1 0 0 1 1 1 0 Podoplanin FAP PF07174.11 OQS04190.1 - 0.068 12.6 25.1 0.092 12.2 25.1 1.1 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) Phage_holin_2_4 PF16082.5 OQS04190.1 - 0.082 12.6 0.2 0.14 11.9 0.2 1.3 1 0 0 1 1 1 0 Bacteriophage holin family, superfamily II-like LRV_FeS PF05484.11 OQS04190.1 - 7.3 6.7 7.6 2.1 8.4 2.5 2.2 1 1 1 2 2 2 0 LRV protein FeS4 cluster Ank_2 PF12796.7 OQS04191.1 - 5.7e-28 97.3 5.7 1.4e-09 38.4 0.1 4.3 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQS04191.1 - 1.1e-23 83.3 4.3 1.1e-06 29.1 0.1 5.3 2 1 3 5 5 5 5 Ankyrin repeats (many copies) PDZ_6 PF17820.1 OQS04191.1 - 1.9e-15 56.5 0.1 0.00024 20.9 0.0 3.7 3 0 0 3 3 3 3 PDZ domain Ank_5 PF13857.6 OQS04191.1 - 3.1e-13 49.6 5.9 0.00011 22.4 0.1 5.9 3 2 2 5 5 5 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQS04191.1 - 9.1e-13 47.2 3.1 0.00079 19.7 0.0 5.8 6 0 0 6 6 6 3 Ankyrin repeat Ank PF00023.30 OQS04191.1 - 4.6e-11 42.6 7.0 0.0027 18.1 0.0 5.9 7 0 0 7 7 7 4 Ankyrin repeat PDZ_2 PF13180.6 OQS04191.1 - 1.4e-09 38.2 0.0 0.02 15.2 0.0 3.4 3 0 0 3 3 3 3 PDZ domain PDZ PF00595.24 OQS04191.1 - 2.1e-06 28.0 0.0 0.54 10.6 0.0 3.4 3 0 0 3 3 3 3 PDZ domain TPD PF14811.6 OQS04192.1 - 0.029 14.2 0.3 0.079 12.8 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function TPD sequence-motif RimK PF08443.11 OQS04192.1 - 0.19 11.3 1.3 7.9 6.0 0.2 2.4 2 0 0 2 2 2 0 RimK-like ATP-grasp domain CENP-B_dimeris PF09026.10 OQS04192.1 - 0.28 11.6 8.7 0.27 11.6 6.9 1.9 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Cwf_Cwc_15 PF04889.12 OQS04192.1 - 7.8 6.2 9.3 17 5.0 9.3 1.5 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DUF1077 PF06417.12 OQS04193.1 - 1.1e-36 125.4 0.4 1.4e-36 125.1 0.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1077) EF-hand_8 PF13833.6 OQS04194.1 - 1.1e-12 47.6 0.1 0.014 15.2 0.1 5.0 5 0 0 5 5 5 4 EF-hand domain pair EF-hand_6 PF13405.6 OQS04194.1 - 7.2e-10 38.0 3.5 0.0059 16.5 0.0 6.2 6 0 0 6 6 6 2 EF-hand domain EF-hand_7 PF13499.6 OQS04194.1 - 8.1e-10 39.0 2.3 0.0038 17.6 0.0 4.1 2 2 1 3 3 3 3 EF-hand domain pair EF-hand_1 PF00036.32 OQS04194.1 - 4.5e-09 35.2 0.2 0.02 14.4 0.1 4.9 5 0 0 5 5 5 3 EF hand EF-hand_4 PF12763.7 OQS04194.1 - 0.019 14.9 0.0 0.61 10.1 0.0 2.6 2 0 0 2 2 2 0 Cytoskeletal-regulatory complex EF hand Sugarporin_N PF11471.8 OQS04194.1 - 0.022 14.7 0.0 0.47 10.4 0.0 2.5 2 0 0 2 2 2 0 Maltoporin periplasmic N-terminal extension EF-hand_9 PF14658.6 OQS04194.1 - 0.15 12.4 0.0 13 6.2 0.0 3.3 3 0 0 3 3 3 0 EF-hand domain Kelch_5 PF13854.6 OQS04195.1 - 7.6e-07 29.0 1.6 0.3 11.1 0.0 5.1 5 0 0 5 5 5 1 Kelch motif Kelch_1 PF01344.25 OQS04195.1 - 0.00013 21.5 9.4 0.047 13.3 0.0 5.4 6 0 0 6 6 6 2 Kelch motif Kelch_6 PF13964.6 OQS04195.1 - 0.0015 18.8 13.9 2.1 8.8 0.1 5.2 6 0 0 6 6 6 3 Kelch motif Kelch_3 PF13415.6 OQS04195.1 - 0.0015 18.7 26.2 0.014 15.6 0.2 6.1 6 1 0 6 6 6 3 Galactose oxidase, central domain RAG2 PF03089.14 OQS04195.1 - 0.091 11.7 0.0 2.1 7.3 0.0 2.3 1 1 0 1 1 1 0 Recombination activating protein 2 DUF2116 PF09889.9 OQS04196.1 - 3.9 7.5 14.5 7.8 6.6 4.9 3.3 2 0 0 2 2 2 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) Transketolase_C PF02780.20 OQS04197.1 - 0.18 11.7 0.0 0.27 11.1 0.0 1.3 1 0 0 1 1 1 0 Transketolase, C-terminal domain LRR_9 PF14580.6 OQS04198.1 - 2.5e-24 85.7 20.5 1.1e-13 51.0 6.4 3.4 2 1 1 3 3 3 3 Leucine-rich repeat LRR_4 PF12799.7 OQS04198.1 - 2e-22 78.9 47.5 4.8e-06 26.8 3.1 7.2 5 2 2 7 7 7 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 OQS04198.1 - 3.5e-13 49.1 43.6 1.2e-05 24.9 10.1 6.7 4 2 3 7 7 7 6 Leucine rich repeat PX PF00787.24 OQS04199.1 - 4e-14 52.6 5.2 3.7e-07 30.1 0.2 3.1 3 0 0 3 3 3 2 PX domain Tim17 PF02466.19 OQS04199.1 - 0.00099 19.5 1.0 0.015 15.6 0.3 2.4 2 0 0 2 2 2 1 Tim17/Tim22/Tim23/Pmp24 family RecR PF02132.15 OQS04199.1 - 0.082 12.5 0.8 7.9 6.1 0.0 2.8 2 0 0 2 2 2 0 RecR protein Zn-ribbon_8 PF09723.10 OQS04199.1 - 0.14 12.3 4.6 4.5 7.5 0.0 3.9 4 0 0 4 4 4 0 Zinc ribbon domain FYVE PF01363.21 OQS04200.1 - 2.6e-16 59.5 11.0 2.6e-16 59.5 11.0 1.7 2 0 0 2 2 2 1 FYVE zinc finger WEMBL PF05701.11 OQS04200.1 - 0.085 11.5 0.1 0.12 11.1 0.1 1.1 1 0 0 1 1 1 0 Weak chloroplast movement under blue light FYVE_2 PF02318.16 OQS04200.1 - 0.47 10.7 12.8 0.16 12.2 8.2 2.4 1 1 1 2 2 2 0 FYVE-type zinc finger HypA PF01155.19 OQS04200.1 - 0.9 9.6 5.1 2.5 8.1 0.2 2.7 2 1 1 3 3 3 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA GAS PF13851.6 OQS04201.1 - 1.3e-65 220.5 28.6 1.3e-65 220.5 28.6 2.3 2 0 0 2 2 2 1 Growth-arrest specific micro-tubule binding IFT20 PF14931.6 OQS04201.1 - 0.014 15.6 7.6 0.014 15.6 7.6 3.6 2 2 2 4 4 4 0 Intraflagellar transport complex B, subunit 20 NMT1_3 PF16868.5 OQS04201.1 - 0.087 12.2 0.8 5.6 6.3 0.1 2.2 2 0 0 2 2 2 0 NMT1-like family ATPase PF06745.13 OQS04201.1 - 1.3 8.3 14.1 0.63 9.3 0.9 2.5 1 1 0 2 2 2 0 KaiC DUF883 PF05957.13 OQS04201.1 - 6.4 7.5 21.2 1.3 9.7 0.1 4.2 2 1 1 4 4 4 0 Bacterial protein of unknown function (DUF883) Filament PF00038.21 OQS04201.1 - 8.6 5.8 46.8 1.3 8.5 2.0 3.0 1 1 0 2 2 2 0 Intermediate filament protein BRX PF08381.11 OQS04203.1 - 3.7e-05 23.0 0.9 0.00012 21.4 0.9 1.8 1 0 0 1 1 1 1 Transcription factor regulating root and shoot growth via Pin3 NOA36 PF06524.12 OQS04203.1 - 0.21 10.9 9.2 0.27 10.5 5.3 2.1 2 0 0 2 2 2 0 NOA36 protein CENP-B_dimeris PF09026.10 OQS04203.1 - 2.5 8.5 9.2 6.4 7.2 9.2 1.7 1 0 0 1 1 1 0 Centromere protein B dimerisation domain WD40 PF00400.32 OQS04204.1 - 2.6e-08 34.4 1.1 0.0016 19.2 0.1 3.9 3 0 0 3 3 3 2 WD domain, G-beta repeat PQQ PF01011.21 OQS04204.1 - 0.00075 19.3 0.2 0.025 14.5 0.1 2.8 3 0 0 3 3 3 1 PQQ enzyme repeat ANAPC4_WD40 PF12894.7 OQS04204.1 - 0.0077 16.5 0.0 5.8 7.3 0.0 3.7 3 1 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain RAB3GAP2_N PF14655.6 OQS04204.1 - 0.031 13.6 0.0 0.049 12.9 0.0 1.2 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus TFIIIC_delta PF12657.7 OQS04204.1 - 0.055 13.4 0.0 0.07 13.0 0.0 1.3 1 0 0 1 1 1 0 Transcription factor IIIC subunit delta N-term Myosin_head PF00063.21 OQS04205.1 - 1e-138 463.5 1.0 1.2e-138 463.4 1.0 1.0 1 0 0 1 1 1 1 Myosin head (motor domain) AAA_22 PF13401.6 OQS04205.1 - 0.00026 21.3 0.2 0.032 14.5 0.0 2.7 2 2 0 2 2 2 1 AAA domain AAA_16 PF13191.6 OQS04205.1 - 0.0067 16.8 0.0 0.033 14.6 0.0 2.1 2 1 0 2 2 2 1 AAA ATPase domain Corona_NSP4_C PF16348.5 OQS04205.1 - 0.029 15.2 0.2 0.29 12.0 0.0 2.5 2 0 0 2 2 2 0 Coronavirus nonstructural protein 4 C-terminus Hpr_kinase_C PF07475.12 OQS04205.1 - 0.065 12.8 0.0 3.4 7.2 0.0 2.3 2 0 0 2 2 2 0 HPr Serine kinase C-terminal domain AAA_18 PF13238.6 OQS04205.1 - 0.075 13.6 0.0 0.16 12.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 OQS04205.1 - 0.095 13.0 0.0 0.2 12.0 0.0 1.8 1 1 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 OQS04205.1 - 0.11 12.2 0.0 0.24 11.1 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain SYS1 PF09801.9 OQS04206.1 - 1.7e-40 138.5 2.3 2e-40 138.2 2.3 1.0 1 0 0 1 1 1 1 Integral membrane protein S linking to the trans Golgi network DUF4267 PF14087.6 OQS04206.1 - 0.18 11.9 4.3 0.053 13.6 1.4 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4267) Kei1 PF08552.11 OQS04206.1 - 0.44 10.4 4.1 0.7 9.7 4.1 1.4 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 zf-RING_2 PF13639.6 OQS04207.1 - 2.5e-14 53.3 6.5 3.9e-14 52.7 6.5 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 OQS04207.1 - 3.9e-12 45.7 2.9 7.3e-12 44.8 2.9 1.5 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 OQS04207.1 - 3.6e-10 39.5 7.0 7.1e-10 38.6 7.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 OQS04207.1 - 2.8e-08 33.5 5.5 4.5e-08 32.8 5.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 OQS04207.1 - 2.1e-07 31.1 9.1 1.5e-06 28.4 9.1 2.1 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 OQS04207.1 - 1e-06 28.5 3.7 1.5e-06 28.0 3.7 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 OQS04207.1 - 3e-06 27.1 6.8 5.9e-06 26.2 6.8 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 OQS04207.1 - 9.7e-05 22.2 3.1 0.00015 21.5 3.1 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 OQS04207.1 - 0.001 19.0 4.8 0.0027 17.7 4.8 1.7 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_ribbon_17 PF17120.5 OQS04207.1 - 0.013 15.1 6.3 0.013 15.1 6.3 1.6 2 0 0 2 2 1 0 Zinc-ribbon, C4HC2 type Prok-RING_1 PF14446.6 OQS04207.1 - 0.016 15.2 3.6 0.093 12.7 1.1 2.2 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 FANCL_C PF11793.8 OQS04207.1 - 0.032 14.4 2.0 0.032 14.4 2.0 1.8 1 1 0 1 1 1 0 FANCL C-terminal domain Prok-RING_4 PF14447.6 OQS04207.1 - 0.068 13.0 4.3 0.13 12.2 4.3 1.5 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 PHD PF00628.29 OQS04207.1 - 0.072 13.0 4.5 0.13 12.2 4.5 1.4 1 0 0 1 1 1 0 PHD-finger Baculo_RING PF05883.11 OQS04207.1 - 0.084 12.9 0.3 0.15 12.1 0.3 1.5 1 1 0 1 1 1 0 Baculovirus U-box/Ring-like domain zf-C3HC4_4 PF15227.6 OQS04207.1 - 0.1 12.8 2.7 1.4 9.1 4.1 2.2 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.6 OQS04207.1 - 0.11 12.3 3.0 0.21 11.4 3.0 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-Nse PF11789.8 OQS04207.1 - 0.19 11.6 2.1 0.35 10.7 2.1 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-C3H2C3 PF17122.5 OQS04207.1 - 3.7 7.7 7.1 11 6.2 7.3 1.8 1 1 0 1 1 1 0 Zinc-finger F-box-like PF12937.7 OQS04208.1 - 9.4e-05 22.2 1.5 0.0003 20.6 1.5 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 OQS04208.1 - 0.00072 19.4 1.3 0.0025 17.7 1.3 1.9 1 0 0 1 1 1 1 F-box domain Pkinase PF00069.25 OQS04208.1 - 0.095 12.1 0.0 0.19 11.1 0.0 1.4 1 0 0 1 1 1 0 Protein kinase domain Pkinase_Tyr PF07714.17 OQS04208.1 - 0.15 11.3 0.0 0.28 10.4 0.0 1.4 1 0 0 1 1 1 0 Protein tyrosine kinase ABC_tran PF00005.27 OQS04209.1 - 1.2e-28 100.4 0.0 1.8e-28 99.7 0.0 1.3 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.23 OQS04209.1 - 1.7e-26 93.5 6.0 2.6e-26 92.9 6.0 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.19 OQS04209.1 - 8.9e-07 28.6 1.3 0.0004 19.9 0.1 2.3 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 OQS04209.1 - 0.0011 19.1 0.3 0.0029 17.7 0.2 1.9 1 1 1 2 2 2 1 50S ribosome-binding GTPase AAA_21 PF13304.6 OQS04209.1 - 0.0056 16.5 0.2 0.4 10.4 0.1 2.4 1 1 1 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system DUF87 PF01935.17 OQS04209.1 - 0.013 15.6 0.2 0.029 14.4 0.2 1.5 1 0 0 1 1 1 0 Helicase HerA, central domain TrwB_AAD_bind PF10412.9 OQS04209.1 - 0.028 13.3 1.0 1.3 7.9 0.2 2.9 3 1 0 3 3 3 0 Type IV secretion-system coupling protein DNA-binding domain AAA_22 PF13401.6 OQS04209.1 - 0.031 14.5 0.1 4.3 7.6 0.0 2.5 2 0 0 2 2 2 0 AAA domain DEAD PF00270.29 OQS04209.1 - 0.063 13.0 0.3 0.36 10.6 0.3 2.2 1 1 0 1 1 1 0 DEAD/DEAH box helicase AAA_23 PF13476.6 OQS04209.1 - 0.076 13.5 0.1 0.14 12.6 0.1 1.3 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 OQS04209.1 - 0.08 12.7 0.2 3.3 7.4 0.0 2.3 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_30 PF13604.6 OQS04209.1 - 0.27 11.0 0.4 13 5.5 0.0 2.2 2 0 0 2 2 2 0 AAA domain CwfJ_C_1 PF04677.15 OQS04213.1 - 1.2e-26 92.9 0.0 2.1e-26 92.2 0.0 1.4 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 CwfJ_C_2 PF04676.14 OQS04213.1 - 2e-25 89.5 0.1 2e-25 89.5 0.1 2.5 3 0 0 3 3 3 1 Protein similar to CwfJ C-terminus 2 IQCJ-SCHIP1 PF15157.6 OQS04215.1 - 1.1 9.1 3.5 17 5.2 0.6 2.4 1 1 1 2 2 2 0 Fusion protein IQCJ-SCHIP1 with IQ-like motif IQ PF00612.27 OQS04215.1 - 1.5 8.8 6.2 0.38 10.7 1.2 2.6 2 0 0 2 2 2 0 IQ calmodulin-binding motif ABC_membrane PF00664.23 OQS04216.1 - 4.3e-103 344.7 23.7 5.6e-54 183.6 1.4 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 OQS04216.1 - 6.2e-67 224.3 0.0 5.4e-33 114.4 0.0 2.5 2 0 0 2 2 2 2 ABC transporter Methyltransf_31 PF13847.6 OQS04216.1 - 1.2e-13 51.1 0.0 2.9e-13 49.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 OQS04216.1 - 3.3e-12 46.3 0.0 7.6e-12 45.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain SMC_N PF02463.19 OQS04216.1 - 3e-11 43.2 1.7 0.0016 17.9 0.0 4.1 3 1 0 4 4 4 2 RecF/RecN/SMC N terminal domain Methyltransf_25 PF13649.6 OQS04216.1 - 6.5e-11 42.8 0.0 3.1e-10 40.6 0.0 2.3 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 OQS04216.1 - 1.3e-08 34.7 0.0 2.9e-08 33.5 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) PrmC_N PF17827.1 OQS04216.1 - 2.1e-08 34.6 0.2 7e-08 33.0 0.2 2.0 1 0 0 1 1 1 1 PrmC N-terminal domain AAA_29 PF13555.6 OQS04216.1 - 2e-07 30.6 0.9 0.0079 15.9 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain UPF0020 PF01170.18 OQS04216.1 - 2.2e-06 27.5 0.0 4.9e-06 26.4 0.0 1.5 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 AAA PF00004.29 OQS04216.1 - 2.7e-06 27.9 1.9 0.0085 16.5 0.0 4.0 2 2 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 OQS04216.1 - 7.6e-06 26.4 1.5 0.081 13.3 0.4 2.9 2 1 0 2 2 2 2 AAA ATPase domain Zeta_toxin PF06414.12 OQS04216.1 - 4.3e-05 22.9 0.0 0.038 13.3 0.0 2.5 2 0 0 2 2 2 1 Zeta toxin Methyltransf_10 PF05971.12 OQS04216.1 - 6.4e-05 22.4 0.0 0.00012 21.5 0.0 1.3 1 0 0 1 1 1 1 RNA methyltransferase Methyltransf_11 PF08241.12 OQS04216.1 - 9.6e-05 23.0 0.0 0.00038 21.1 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.15 OQS04216.1 - 0.00013 21.7 0.0 0.00086 19.0 0.0 2.2 2 0 0 2 2 2 1 Conserved hypothetical protein 95 AAA_21 PF13304.6 OQS04216.1 - 0.00022 21.1 0.2 2.6 7.8 0.0 3.6 4 0 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_25 PF13481.6 OQS04216.1 - 0.00032 20.3 1.5 0.97 9.0 0.0 3.5 4 0 0 4 4 4 2 AAA domain Methyltransf_23 PF13489.6 OQS04216.1 - 0.0005 19.9 0.0 0.0021 17.9 0.0 2.0 2 1 0 2 2 2 1 Methyltransferase domain N6_Mtase PF02384.16 OQS04216.1 - 0.00052 19.4 0.0 0.0015 17.8 0.0 1.7 2 0 0 2 2 1 1 N-6 DNA Methylase Methyltransf_12 PF08242.12 OQS04216.1 - 0.00054 20.6 0.0 0.0019 18.9 0.0 2.0 2 0 0 2 2 1 1 Methyltransferase domain AAA_30 PF13604.6 OQS04216.1 - 0.0006 19.6 1.5 0.79 9.4 0.3 3.2 2 2 0 2 2 2 2 AAA domain AAA_22 PF13401.6 OQS04216.1 - 0.00061 20.1 3.1 0.37 11.1 0.0 3.7 2 2 0 2 2 2 1 AAA domain ABC_ATPase PF09818.9 OQS04216.1 - 0.00063 18.7 0.5 0.51 9.1 0.1 2.5 2 0 0 2 2 2 2 Predicted ATPase of the ABC class RsgA_GTPase PF03193.16 OQS04216.1 - 0.00094 19.1 0.2 1.6 8.6 0.1 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_18 PF13238.6 OQS04216.1 - 0.0011 19.5 0.0 3.9 8.0 0.0 3.4 3 0 0 3 3 3 0 AAA domain DUF87 PF01935.17 OQS04216.1 - 0.0011 19.1 0.1 2.8 8.0 0.0 2.9 3 0 0 3 3 2 2 Helicase HerA, central domain AAA_7 PF12775.7 OQS04216.1 - 0.0012 18.4 0.0 0.69 9.4 0.0 2.5 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_5 PF07728.14 OQS04216.1 - 0.0014 18.6 0.7 1.3 9.0 0.0 4.0 4 0 0 4 4 4 1 AAA domain (dynein-related subfamily) G-alpha PF00503.20 OQS04216.1 - 0.0014 17.9 0.1 1.1 8.3 0.0 2.5 3 0 0 3 3 2 2 G-protein alpha subunit AAA_33 PF13671.6 OQS04216.1 - 0.0029 17.7 0.1 2 8.6 0.0 2.9 3 0 0 3 3 2 1 AAA domain Methyltransf_18 PF12847.7 OQS04216.1 - 0.0038 17.2 0.0 0.012 15.6 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain AAA_15 PF13175.6 OQS04216.1 - 0.0039 16.9 0.0 1.9 8.1 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain SbcCD_C PF13558.6 OQS04216.1 - 0.0051 17.0 3.4 4.4 7.6 0.3 4.1 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit CMAS PF02353.20 OQS04216.1 - 0.009 15.3 0.0 0.017 14.4 0.0 1.4 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase AAA_24 PF13479.6 OQS04216.1 - 0.017 14.9 1.1 1.8 8.3 0.0 3.1 4 0 0 4 4 3 0 AAA domain DOT1 PF08123.13 OQS04216.1 - 0.017 14.6 0.0 0.057 12.9 0.0 1.8 2 0 0 2 2 1 0 Histone methylation protein DOT1 Methyltransf_15 PF09445.10 OQS04216.1 - 0.018 14.6 0.0 0.037 13.6 0.0 1.5 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase DEAD PF00270.29 OQS04216.1 - 0.022 14.5 1.3 7.9 6.2 0.1 3.4 2 2 0 2 2 2 0 DEAD/DEAH box helicase AAA_28 PF13521.6 OQS04216.1 - 0.042 14.1 0.0 15 5.8 0.0 2.8 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.6 OQS04216.1 - 0.054 14.0 0.2 6 7.3 0.0 2.6 2 0 0 2 2 2 0 AAA domain APS_kinase PF01583.20 OQS04216.1 - 0.056 13.3 0.1 3 7.7 0.0 2.4 2 0 0 2 2 2 0 Adenylylsulphate kinase NTPase_1 PF03266.15 OQS04216.1 - 0.067 13.1 0.3 9.9 6.0 0.0 3.4 3 0 0 3 3 3 0 NTPase MMR_HSR1 PF01926.23 OQS04216.1 - 0.068 13.3 0.8 17 5.5 0.0 3.2 3 0 0 3 3 2 0 50S ribosome-binding GTPase ATP_bind_1 PF03029.17 OQS04216.1 - 0.076 12.8 0.0 5.6 6.7 0.0 2.3 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_17 PF13207.6 OQS04216.1 - 0.33 11.4 1.4 33 4.9 0.0 3.7 5 0 0 5 5 2 0 AAA domain AAA_5 PF07728.14 OQS04217.1 - 6.9e-08 32.6 0.1 2.2e-07 30.9 0.1 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Torsin PF06309.11 OQS04217.1 - 2.8e-07 30.7 0.0 5.9e-07 29.6 0.0 1.5 1 1 0 1 1 1 1 Torsin AAA_16 PF13191.6 OQS04217.1 - 2.7e-06 27.9 0.0 6.2e-05 23.4 0.0 2.2 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 OQS04217.1 - 6.7e-06 26.4 0.1 2.3e-05 24.7 0.1 1.9 1 1 0 1 1 1 1 AAA domain AAA PF00004.29 OQS04217.1 - 1.6e-05 25.4 0.0 3.5e-05 24.2 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ResIII PF04851.15 OQS04217.1 - 2.5e-05 24.4 0.2 7.9e-05 22.7 0.2 1.7 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_14 PF13173.6 OQS04217.1 - 6.5e-05 23.0 0.0 0.00011 22.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.12 OQS04217.1 - 0.00015 21.5 0.0 0.089 12.5 0.0 2.2 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain RNA_helicase PF00910.22 OQS04217.1 - 0.00067 20.0 0.0 0.0048 17.3 0.0 2.3 1 1 0 1 1 1 1 RNA helicase AAA_18 PF13238.6 OQS04217.1 - 0.0013 19.2 0.0 0.0026 18.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_23 PF13476.6 OQS04217.1 - 0.0041 17.6 0.0 0.0047 17.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 OQS04217.1 - 0.0042 17.4 1.0 0.035 14.4 1.0 2.1 1 1 0 1 1 1 1 AAA domain PhoH PF02562.16 OQS04217.1 - 0.0046 16.4 0.1 0.13 11.7 0.0 2.3 2 0 0 2 2 2 1 PhoH-like protein AAA_2 PF07724.14 OQS04217.1 - 0.0062 16.7 0.1 0.02 15.0 0.1 1.8 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_11 PF13086.6 OQS04217.1 - 0.0073 16.1 0.0 0.098 12.4 0.0 2.2 2 0 0 2 2 2 1 AAA domain ATPase_2 PF01637.18 OQS04217.1 - 0.01 15.8 0.2 0.61 10.0 0.2 2.4 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea DUF87 PF01935.17 OQS04217.1 - 0.044 13.9 0.0 0.11 12.6 0.0 1.6 1 0 0 1 1 1 0 Helicase HerA, central domain AAA_30 PF13604.6 OQS04217.1 - 0.045 13.5 0.7 0.12 12.1 0.7 1.7 1 1 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 OQS04217.1 - 0.072 12.4 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_24 PF13479.6 OQS04217.1 - 0.074 12.8 0.0 0.16 11.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 OQS04217.1 - 0.076 13.3 0.0 0.13 12.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.15 OQS04217.1 - 0.094 12.6 0.0 0.26 11.2 0.0 1.7 2 0 0 2 2 2 0 Rad17 P-loop domain T2SSE PF00437.20 OQS04217.1 - 0.095 11.7 0.6 0.21 10.6 0.5 1.6 1 1 0 1 1 1 0 Type II/IV secretion system protein L51_S25_CI-B8 PF05047.16 OQS04217.1 - 0.097 12.6 0.1 1.2 9.2 0.0 2.4 2 0 0 2 2 2 0 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain Sigma54_activat PF00158.26 OQS04217.1 - 0.11 12.3 0.0 0.24 11.1 0.0 1.6 2 0 0 2 2 2 0 Sigma-54 interaction domain Pkinase PF00069.25 OQS04218.1 - 1.8e-12 47.2 1.1 6.2e-12 45.4 0.0 2.4 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQS04218.1 - 5.2e-09 35.8 0.0 1e-08 34.8 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase KH_8 PF17903.1 OQS04218.1 - 0.00077 19.5 0.0 0.0032 17.5 0.0 2.0 1 0 0 1 1 1 1 Krr1 KH1 domain WW PF00397.26 OQS04218.1 - 0.0088 16.1 0.5 0.027 14.5 0.2 2.1 2 0 0 2 2 2 1 WW domain KH_1 PF00013.29 OQS04218.1 - 0.0092 15.8 0.1 0.021 14.7 0.1 1.6 1 0 0 1 1 1 1 KH domain DUF3381 PF11861.8 OQS04218.1 - 0.016 15.0 8.5 0.045 13.5 8.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3381) HrcA PF01628.21 OQS04218.1 - 3.2 7.6 8.0 0.18 11.7 2.3 1.8 2 0 0 2 2 2 0 HrcA protein C terminal domain Myb_DNA-binding PF00249.31 OQS04219.1 - 7e-12 45.3 0.0 1.2e-11 44.6 0.0 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Polysacc_deac_2 PF04748.13 OQS04219.1 - 0.074 12.2 0.0 0.085 12.0 0.0 1.2 1 0 0 1 1 1 0 Divergent polysaccharide deacetylase Peptidase_M16_M PF16187.5 OQS04220.1 - 5.3e-90 301.5 2.4 5.3e-90 301.5 2.4 2.0 2 0 0 2 2 2 1 Middle or third domain of peptidase_M16 Peptidase_M16 PF00675.20 OQS04220.1 - 9.8e-41 139.2 0.3 2.7e-40 137.7 0.3 1.8 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 OQS04220.1 - 1.5e-33 116.3 0.1 2.6e-22 79.7 0.0 2.6 2 0 0 2 2 2 2 Peptidase M16 inactive domain Mpv17_PMP22 PF04117.12 OQS04221.1 - 0.076 13.2 0.1 0.19 12.0 0.1 1.6 1 0 0 1 1 1 0 Mpv17 / PMP22 family Ank_2 PF12796.7 OQS04224.1 - 3.5e-11 43.5 1.4 2.1e-05 25.0 0.2 2.6 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OQS04224.1 - 1.4e-09 38.0 0.1 0.019 15.3 0.0 4.2 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 OQS04224.1 - 1.6e-07 31.7 0.5 1.8e-05 25.2 0.0 3.0 2 1 0 2 2 2 1 Ankyrin repeats (many copies) DUF5049 PF16468.5 OQS04224.1 - 0.00077 19.3 2.9 2.4 8.1 0.0 4.0 2 1 3 5 5 5 2 Domain of unknown function (DUF5049) Ank_3 PF13606.6 OQS04224.1 - 0.0011 19.3 0.3 11 7.0 0.0 4.1 3 1 1 4 4 4 1 Ankyrin repeat Ank PF00023.30 OQS04224.1 - 0.15 12.6 0.0 24 5.6 0.0 2.9 2 1 0 2 2 2 0 Ankyrin repeat FYVE PF01363.21 OQS04225.1 - 9.1e-19 67.4 33.1 3.1e-11 43.2 10.6 2.4 2 0 0 2 2 2 2 FYVE zinc finger GAF PF01590.26 OQS04225.1 - 2.4e-06 28.2 0.0 5.7e-06 27.0 0.0 1.7 1 0 0 1 1 1 1 GAF domain FYVE_2 PF02318.16 OQS04225.1 - 0.00037 20.7 19.3 0.053 13.7 5.8 2.5 2 0 0 2 2 2 2 FYVE-type zinc finger Siva PF05458.12 OQS04225.1 - 0.0058 16.3 3.9 0.0058 16.3 3.9 2.4 2 0 0 2 2 2 2 Cd27 binding protein (Siva) IBR PF01485.21 OQS04225.1 - 0.26 11.5 22.0 0.57 10.5 8.0 2.9 2 0 0 2 2 2 0 IBR domain, a half RING-finger domain FYVE PF01363.21 OQS04226.1 - 3.5e-10 39.9 5.7 3.8e-10 39.8 5.7 1.1 1 0 0 1 1 1 1 FYVE zinc finger Siva PF05458.12 OQS04226.1 - 0.019 14.6 3.2 0.022 14.4 3.2 1.1 1 0 0 1 1 1 0 Cd27 binding protein (Siva) FYVE_2 PF02318.16 OQS04226.1 - 0.026 14.7 3.3 0.031 14.5 3.3 1.1 1 0 0 1 1 1 0 FYVE-type zinc finger Myb_DNA-binding PF00249.31 OQS04227.1 - 2e-15 56.7 2.6 3.9e-11 42.9 0.3 2.9 2 1 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OQS04227.1 - 3e-14 53.0 0.1 1.7e-12 47.4 0.0 2.4 1 1 1 2 2 2 2 Myb-like DNA-binding domain AAA_25 PF13481.6 OQS04228.1 - 1.1e-20 74.1 0.0 2.2e-20 73.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain ATPase PF06745.13 OQS04228.1 - 5e-16 58.7 0.1 7.4e-14 51.6 0.1 2.1 1 1 0 1 1 1 1 KaiC DnaB_C PF03796.15 OQS04228.1 - 6.7e-12 45.3 0.9 2.4e-06 27.1 0.2 2.3 1 1 1 2 2 2 2 DnaB-like helicase C terminal domain Rad51 PF08423.11 OQS04228.1 - 4.6e-07 29.4 0.0 2e-06 27.3 0.0 1.9 1 1 0 1 1 1 1 Rad51 AAA_24 PF13479.6 OQS04228.1 - 2e-06 27.7 0.1 4.5e-05 23.3 0.0 2.8 2 1 0 2 2 2 1 AAA domain Rubredoxin_2 PF18073.1 OQS04228.1 - 2.2e-06 27.3 7.2 3.5e-06 26.6 7.2 1.3 1 0 0 1 1 1 1 Rubredoxin metal binding domain ChlI PF13541.6 OQS04228.1 - 3.5e-06 26.9 0.1 8.3e-06 25.7 0.1 1.6 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase DUF2075 PF09848.9 OQS04228.1 - 1.1e-05 24.9 0.0 1.7e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) Lon_C PF05362.13 OQS04228.1 - 3.1e-05 23.6 0.0 6.2e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain AAA_22 PF13401.6 OQS04228.1 - 7.7e-05 23.0 0.0 0.00014 22.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 OQS04228.1 - 0.00013 22.4 0.0 0.00029 21.3 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RecA PF00154.21 OQS04228.1 - 0.0004 19.9 0.1 0.00059 19.4 0.1 1.2 1 0 0 1 1 1 1 recA bacterial DNA recombination protein GvpD PF07088.11 OQS04228.1 - 0.0022 16.7 0.1 0.01 14.5 0.1 1.8 1 1 0 1 1 1 1 GvpD gas vesicle protein KTI12 PF08433.10 OQS04228.1 - 0.006 16.1 0.0 0.013 15.0 0.0 1.4 1 1 0 1 1 1 1 Chromatin associated protein KTI12 NACHT PF05729.12 OQS04228.1 - 0.0068 16.3 0.0 0.01 15.8 0.0 1.4 1 0 0 1 1 1 1 NACHT domain AAA_18 PF13238.6 OQS04228.1 - 0.0072 16.9 0.0 0.014 16.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 OQS04228.1 - 0.0075 16.7 0.0 0.016 15.6 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.14 OQS04228.1 - 0.009 16.0 0.0 0.019 14.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_30 PF13604.6 OQS04228.1 - 0.0096 15.7 0.0 0.016 14.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 OQS04228.1 - 0.013 15.9 0.1 0.028 14.8 0.1 1.6 1 0 0 1 1 1 0 RNA helicase ABC_tran PF00005.27 OQS04228.1 - 0.019 15.5 0.1 0.031 14.8 0.1 1.4 1 0 0 1 1 1 0 ABC transporter IstB_IS21 PF01695.17 OQS04228.1 - 0.034 13.9 0.2 0.099 12.4 0.0 1.8 2 0 0 2 2 1 0 IstB-like ATP binding protein AAA_14 PF13173.6 OQS04228.1 - 0.047 13.7 0.0 0.14 12.2 0.0 1.7 1 1 0 1 1 1 0 AAA domain RuvB_N PF05496.12 OQS04228.1 - 0.073 12.8 0.0 0.18 11.5 0.0 1.7 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain Viral_helicase1 PF01443.18 OQS04228.1 - 0.078 12.7 0.1 0.14 11.9 0.1 1.6 1 1 0 1 1 1 0 Viral (Superfamily 1) RNA helicase NB-ARC PF00931.22 OQS04228.1 - 0.078 12.1 0.0 0.13 11.5 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain AAA_29 PF13555.6 OQS04228.1 - 0.15 11.8 0.1 0.35 10.6 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain GSP_synth PF03738.14 OQS04229.1 - 2e-70 237.9 0.0 2.5e-70 237.5 0.0 1.1 1 0 0 1 1 1 1 Glutathionylspermidine synthase preATP-grasp DUF3343 PF11823.8 OQS04229.1 - 0.064 12.7 0.2 0.13 11.7 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3343) Ricin_B_lectin PF00652.22 OQS04230.1 - 1.9e-16 60.5 4.7 8.6e-11 42.2 0.5 2.5 2 1 0 2 2 2 2 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.6 OQS04230.1 - 4.3e-06 27.3 1.0 0.0052 17.5 0.1 2.9 2 1 0 2 2 2 2 Ricin-type beta-trefoil lectin domain-like Acetyltransf_1 PF00583.25 OQS04231.1 - 3.8e-15 56.1 0.0 8.2e-15 55.1 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 OQS04231.1 - 5.8e-09 36.3 0.0 1.4e-08 35.0 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 OQS04231.1 - 1.1e-08 35.0 0.1 3.2e-08 33.6 0.1 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 OQS04231.1 - 1.3e-06 29.1 0.0 3.2e-06 27.9 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 OQS04231.1 - 0.00021 21.2 0.0 0.00041 20.2 0.0 1.5 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_4 PF13420.7 OQS04231.1 - 0.00027 21.1 0.1 0.00069 19.8 0.1 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 OQS04231.1 - 0.00094 18.9 0.0 0.0025 17.5 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 OQS04231.1 - 0.0064 16.6 0.0 0.02 15.0 0.0 1.9 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain TssO PF17561.2 OQS04231.1 - 0.072 13.2 9.3 0.1 12.7 1.4 3.0 3 0 0 3 3 3 0 Type VI secretion system, TssO Kinocilin PF15033.6 OQS04231.1 - 0.71 9.5 1.8 1.8 8.2 1.8 1.6 1 0 0 1 1 1 0 Kinocilin protein DUF4547 PF15080.6 OQS04232.1 - 2.7e-06 27.2 4.3 2.7 7.6 0.0 5.4 6 0 0 6 6 6 3 Domain of unknown function (DUF4547) PreAtp-grasp PF18604.1 OQS04232.1 - 0.034 13.8 0.1 11 5.6 0.0 3.0 2 0 0 2 2 2 0 Pre ATP-grasp domain DUF3446 PF11928.8 OQS04232.1 - 0.71 10.2 4.8 23 5.4 0.1 2.9 2 0 0 2 2 2 0 Early growth response N-terminal domain Retrotrans_gag PF03732.17 OQS04233.1 - 0.0015 18.8 0.0 0.0064 16.8 0.0 2.0 1 1 0 1 1 1 1 Retrotransposon gag protein Rif1_N PF12231.8 OQS04234.1 - 9.9e-26 90.6 1.9 1.1e-25 90.5 0.7 1.7 2 0 0 2 2 2 1 Rap1-interacting factor 1 N terminal RTP1_C1 PF10363.9 OQS04234.1 - 0.027 14.6 0.1 12 6.1 0.0 3.6 3 1 0 3 3 3 0 Required for nuclear transport of RNA pol II C-terminus 1 Cdc6_C PF09079.11 OQS04234.1 - 0.075 13.0 0.0 0.17 11.9 0.0 1.5 1 0 0 1 1 1 0 CDC6, C terminal winged helix domain Pkinase PF00069.25 OQS04236.1 - 3.7e-60 203.5 0.0 4.9e-60 203.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Ras PF00071.22 OQS04236.1 - 5.8e-32 110.5 0.0 8.6e-32 110.0 0.0 1.3 1 0 0 1 1 1 1 Ras family Pkinase_Tyr PF07714.17 OQS04236.1 - 8.8e-23 80.9 0.0 1.3e-22 80.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Roc PF08477.13 OQS04236.1 - 2.3e-21 76.2 0.0 3.8e-21 75.5 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OQS04236.1 - 3.4e-07 29.9 0.0 5.4e-07 29.2 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Kinase-like PF14531.6 OQS04236.1 - 5.5e-07 29.2 0.0 8.2e-07 28.6 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 OQS04236.1 - 0.0014 18.6 0.2 0.0021 18.0 0.2 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 OQS04236.1 - 0.0091 15.0 0.0 0.014 14.3 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain MMR_HSR1 PF01926.23 OQS04236.1 - 0.03 14.4 0.0 0.11 12.6 0.0 1.9 2 0 0 2 2 2 0 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 OQS04236.1 - 0.13 11.6 0.0 0.21 10.9 0.0 1.3 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region FIVAR PF07554.13 OQS04238.1 - 0.026 15.3 6.9 0.086 13.6 1.4 2.4 2 0 0 2 2 2 0 FIVAR domain GbpA_2 PF18416.1 OQS04238.1 - 0.091 13.1 3.1 0.11 12.7 1.9 1.7 1 1 1 2 2 2 0 N-acetylglucosamine binding protein domain 2 Spore_II_R PF09551.10 OQS04238.1 - 0.7 10.4 7.9 0.93 10.0 2.6 2.1 1 1 1 2 2 2 0 Stage II sporulation protein R (spore_II_R) DUF846 PF05832.12 OQS04239.1 - 4.5e-53 179.0 11.6 9.7e-53 177.9 11.6 1.6 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF846) GCP_N_terminal PF17681.1 OQS04239.1 - 4e-27 95.7 0.1 1.1e-26 94.2 0.1 1.6 1 1 0 1 1 1 1 Gamma tubulin complex component N-terminal GCP_C_terminal PF04130.13 OQS04239.1 - 4.1e-21 75.7 9.2 4.7e-19 69.0 1.4 3.1 2 1 1 3 3 3 3 Gamma tubulin complex component C-terminal Acetyltransf_3 PF13302.7 OQS04240.1 - 3.6e-14 53.6 0.0 5.1e-14 53.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 OQS04240.1 - 0.00011 22.4 0.0 0.00017 21.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.7 OQS04240.1 - 0.0083 16.3 0.0 0.011 15.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF347 PF03988.12 OQS04240.1 - 0.37 11.0 2.8 0.71 10.1 2.8 1.4 1 0 0 1 1 1 0 Repeat of Unknown Function (DUF347) Pur_ac_phosph_N PF16656.5 OQS04241.1 - 0.034 14.7 0.0 0.064 13.8 0.0 1.5 1 0 0 1 1 1 0 Purple acid Phosphatase, N-terminal domain DUF883 PF05957.13 OQS04241.1 - 1.7 9.3 4.7 1.3 9.6 0.2 2.4 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) zf-HIT PF04438.16 OQS04242.1 - 0.053 13.4 0.2 0.09 12.7 0.2 1.3 1 0 0 1 1 1 0 HIT zinc finger Anoctamin PF04547.12 OQS04243.1 - 1.8e-23 83.1 2.2 1.8e-23 83.1 2.2 1.9 1 1 1 2 2 2 2 Calcium-activated chloride channel ELMO_CED12 PF04727.13 OQS04244.1 - 5.3e-40 137.4 0.2 2.3e-39 135.4 0.0 1.9 2 0 0 2 2 2 1 ELMO/CED-12 family UBM PF14377.6 OQS04244.1 - 0.00066 19.0 0.1 0.0021 17.4 0.1 1.8 1 0 0 1 1 1 1 Ubiquitin binding region Vps36-NZF-N PF16988.5 OQS04244.1 - 0.0021 17.4 1.8 0.0065 15.8 1.7 2.0 1 1 0 1 1 1 1 Vacuolar protein sorting 36 NZF-N zinc-finger domain EURL PF06937.11 OQS04244.1 - 0.0051 16.3 0.4 0.0084 15.6 0.4 1.2 1 0 0 1 1 1 1 EURL protein zf-Sec23_Sec24 PF04810.15 OQS04244.1 - 0.051 13.6 0.3 0.14 12.2 0.3 1.7 1 0 0 1 1 1 0 Sec23/Sec24 zinc finger Glu-tRNAGln PF02686.15 OQS04245.1 - 0.029 14.7 0.0 0.086 13.1 0.0 1.8 1 0 0 1 1 1 0 Glu-tRNAGln amidotransferase C subunit zinc_ribbon_6 PF14599.6 OQS04246.1 - 6.3e-22 77.4 3.6 6.3e-22 77.4 3.6 4.0 4 0 0 4 4 4 1 Zinc-ribbon PAP2_C PF14360.6 OQS04246.1 - 1.3e-15 57.7 9.7 1.3e-15 57.7 9.7 3.3 3 0 0 3 3 3 1 PAP2 superfamily C-terminal zf-CHY PF05495.12 OQS04246.1 - 5e-08 33.3 5.4 5e-08 33.3 5.4 4.5 4 1 0 4 4 4 1 CHY zinc finger zf-RING_2 PF13639.6 OQS04246.1 - 2.3e-07 31.0 9.7 2.3e-07 31.0 9.7 4.2 2 1 2 4 4 4 1 Ring finger domain Prok-RING_4 PF14447.6 OQS04246.1 - 0.0041 16.9 1.5 0.0041 16.9 1.5 4.0 2 1 1 3 3 3 2 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 OQS04246.1 - 0.0048 16.8 9.2 0.0048 16.8 9.2 5.1 2 1 2 4 4 4 1 zinc-RING finger domain zf-RING_11 PF17123.5 OQS04246.1 - 0.033 13.9 7.4 0.24 11.2 7.4 2.7 1 0 0 1 1 1 0 RING-like zinc finger DUF2721 PF11026.8 OQS04246.1 - 0.51 10.2 4.6 0.16 11.9 0.7 2.2 2 1 1 3 3 3 0 Protein of unknown function (DUF2721) zf-RING_UBOX PF13445.6 OQS04246.1 - 3.6 7.7 15.3 0.83 9.7 10.3 2.7 2 0 0 2 2 2 0 RING-type zinc-finger LRR_6 PF13516.6 OQS04247.1 - 2.9e-05 23.8 1.2 1.1 9.5 0.2 5.0 5 0 0 5 5 5 2 Leucine Rich repeat UPAR_LY6_2 PF16975.5 OQS04247.1 - 0.077 13.2 0.6 0.077 13.2 0.6 2.8 2 1 1 3 3 3 0 Ly6/PLAUR domain-containing protein 6, Lypd6 adh_short PF00106.25 OQS04248.1 - 4.4e-44 150.3 0.1 6.7e-44 149.7 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OQS04248.1 - 5.5e-24 85.0 0.1 8.4e-24 84.4 0.1 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Glyco_hydro_72 PF03198.14 OQS04248.1 - 7e-17 61.6 0.0 1.3e-16 60.8 0.0 1.4 1 0 0 1 1 1 1 Glucanosyltransferase KR PF08659.10 OQS04248.1 - 1.9e-12 47.4 0.1 3.4e-12 46.6 0.1 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_7 PF13241.6 OQS04248.1 - 0.0013 19.1 0.1 0.0027 18.1 0.1 1.5 1 0 0 1 1 1 1 Putative NAD(P)-binding Pyr_redox_2 PF07992.14 OQS04248.1 - 0.0029 16.9 0.1 0.0045 16.3 0.1 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.18 OQS04248.1 - 0.0069 16.3 0.4 0.011 15.6 0.4 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain THF_DHG_CYH_C PF02882.19 OQS04248.1 - 0.013 14.9 0.1 0.024 13.9 0.1 1.4 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Epimerase PF01370.21 OQS04248.1 - 0.023 14.2 0.1 0.039 13.4 0.1 1.4 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family DFP PF04127.15 OQS04248.1 - 0.03 14.2 0.4 0.077 12.8 0.4 1.7 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein PALP PF00291.25 OQS04248.1 - 0.06 12.7 0.8 0.18 11.2 0.6 1.8 1 1 1 2 2 2 0 Pyridoxal-phosphate dependent enzyme Eno-Rase_NADH_b PF12242.8 OQS04248.1 - 0.08 12.7 0.2 0.21 11.4 0.2 1.7 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase NmrA PF05368.13 OQS04248.1 - 0.3 10.6 1.9 0.47 10.0 1.4 1.6 2 0 0 2 2 2 0 NmrA-like family DEAD PF00270.29 OQS04249.1 - 2.4e-47 161.0 0.6 6.9e-46 156.2 0.2 2.6 3 0 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OQS04249.1 - 2.8e-22 79.2 0.3 1.5e-21 76.8 0.0 2.5 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 OQS04249.1 - 2.1e-16 59.9 2.4 5.4e-16 58.6 0.4 2.6 3 0 0 3 3 3 1 Domain of unknown function (DUF4217) Abhydrolase_1 PF00561.20 OQS04249.1 - 1.4e-13 51.1 0.0 2.3e-12 47.1 0.0 2.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 OQS04249.1 - 1.1e-12 47.8 0.2 4.2e-12 45.8 0.0 2.0 2 0 0 2 2 2 1 Serine aminopeptidase, S33 ResIII PF04851.15 OQS04249.1 - 8.8e-10 38.8 1.4 2.2e-09 37.5 0.0 2.4 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit Ndr PF03096.14 OQS04249.1 - 0.0085 14.8 0.0 0.02 13.6 0.0 1.5 1 0 0 1 1 1 1 Ndr family Abhydrolase_6 PF12697.7 OQS04249.1 - 0.019 15.6 0.0 0.041 14.5 0.0 1.6 1 0 0 1 1 1 0 Alpha/beta hydrolase family P_C10 PF14974.6 OQS04250.1 - 1.8e-17 63.3 0.9 1.5e-16 60.4 0.0 2.6 3 0 0 3 3 3 1 Protein C10 Ig_3 PF13927.6 OQS04250.1 - 8.2e-06 26.3 0.1 0.0018 18.8 0.0 2.5 2 0 0 2 2 2 2 Immunoglobulin domain IQ PF00612.27 OQS04250.1 - 0.00071 19.2 1.4 0.0018 17.9 1.4 1.7 1 0 0 1 1 1 1 IQ calmodulin-binding motif Sun2_CC2 PF18580.1 OQS04250.1 - 1.1 9.6 4.5 0.38 11.0 1.0 2.1 2 0 0 2 2 2 0 SUN2 coiled coil domain 2 NAD_kinase PF01513.21 OQS04251.1 - 3.7e-63 213.5 0.0 7e-63 212.5 0.0 1.4 1 0 0 1 1 1 1 ATP-NAD kinase DAGK_cat PF00781.24 OQS04251.1 - 0.00058 19.5 0.0 0.0012 18.5 0.0 1.5 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain CobN-Mg_chel PF02514.16 OQS04251.1 - 0.00094 17.1 0.0 0.0013 16.6 0.0 1.1 1 0 0 1 1 1 1 CobN/Magnesium Chelatase Pox_A_type_inc PF04508.12 OQS04251.1 - 0.0039 17.0 0.0 0.012 15.4 0.0 1.8 1 0 0 1 1 1 1 Viral A-type inclusion protein repeat PDZ PF00595.24 OQS04252.1 - 7.5e-06 26.2 0.2 1.3e-05 25.4 0.2 1.3 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 OQS04252.1 - 0.00037 20.3 0.0 0.00083 19.1 0.0 1.6 1 0 0 1 1 1 1 PDZ domain Ank_5 PF13857.6 OQS04252.1 - 0.014 15.7 0.0 0.032 14.6 0.0 1.8 1 0 0 1 1 1 0 Ankyrin repeats (many copies) Pex24p PF06398.11 OQS04252.1 - 0.041 12.9 0.1 0.9 8.5 0.0 2.0 2 0 0 2 2 2 0 Integral peroxisomal membrane peroxin PMSR PF01625.21 OQS04253.1 - 4.7e-62 208.7 1.2 5.8e-62 208.4 1.2 1.0 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase PAP2_C PF14360.6 OQS04254.1 - 1.4e-17 64.0 14.4 1.4e-17 64.0 14.4 3.5 3 1 0 3 3 3 1 PAP2 superfamily C-terminal PAP2 PF01569.21 OQS04254.1 - 4.5e-06 26.5 5.7 4.5e-06 26.5 5.7 2.9 3 0 0 3 3 3 1 PAP2 superfamily Ank_2 PF12796.7 OQS04257.1 - 1.2e-25 89.8 8.3 9.2e-10 39.0 0.0 6.3 4 1 0 5 5 5 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OQS04257.1 - 1.1e-21 76.6 6.1 1.1e-05 25.6 0.0 6.7 5 1 1 6 6 6 4 Ankyrin repeats (many copies) Ank_4 PF13637.6 OQS04257.1 - 6.3e-19 68.1 12.8 2.4e-05 24.8 0.1 8.6 8 1 1 9 9 9 4 Ankyrin repeats (many copies) Ank PF00023.30 OQS04257.1 - 1.5e-16 60.0 20.3 0.00013 22.3 0.0 8.6 8 0 0 8 8 8 4 Ankyrin repeat Ank_3 PF13606.6 OQS04257.1 - 2e-14 52.3 11.0 0.015 15.7 0.0 8.7 9 0 0 9 9 9 4 Ankyrin repeat Ustilago_mating PF05722.12 OQS04258.1 - 0.017 14.6 0.1 0.95 8.9 0.1 2.1 2 0 0 2 2 2 0 Ustilago B locus mating-type protein PDZ_6 PF17820.1 OQS04260.1 - 0.00017 21.4 0.0 0.00036 20.3 0.0 1.5 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 OQS04260.1 - 0.00029 21.1 0.0 0.00056 20.2 0.0 1.4 1 0 0 1 1 1 1 PDZ domain TTRAP PF14203.6 OQS04260.1 - 0.042 13.8 6.9 0.67 10.0 1.0 2.5 2 0 0 2 2 2 0 Putative tranposon-transfer assisting protein PDZ_2 PF13180.6 OQS04260.1 - 0.16 12.3 0.0 0.36 11.2 0.0 1.6 1 0 0 1 1 1 0 PDZ domain Proteasome PF00227.26 OQS04261.1 - 1.4e-33 116.0 0.0 1.6e-33 115.8 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit DUF676 PF05057.14 OQS04264.1 - 1.9e-22 79.9 0.2 5.7e-22 78.3 0.2 1.8 1 0 0 1 1 1 1 Putative serine esterase (DUF676) TPR_12 PF13424.6 OQS04264.1 - 1.5e-17 63.7 18.8 3e-08 33.8 2.0 5.4 4 2 2 7 7 6 4 Tetratricopeptide repeat Ank_2 PF12796.7 OQS04264.1 - 8.2e-13 48.8 0.4 8.8e-10 39.0 0.1 3.6 3 0 0 3 3 3 1 Ankyrin repeats (3 copies) TPR_1 PF00515.28 OQS04264.1 - 8.3e-10 38.1 19.0 0.0058 16.4 0.6 6.8 8 0 0 8 8 7 3 Tetratricopeptide repeat TPR_10 PF13374.6 OQS04264.1 - 1.5e-09 37.4 6.1 0.0082 16.0 0.1 5.6 6 0 0 6 6 6 2 Tetratricopeptide repeat Ank_4 PF13637.6 OQS04264.1 - 2.1e-09 37.7 0.3 2.1e-07 31.3 0.0 3.8 3 1 1 4 4 3 2 Ankyrin repeats (many copies) TPR_2 PF07719.17 OQS04264.1 - 3.7e-09 36.0 28.6 0.017 15.2 0.5 9.0 11 0 0 11 11 9 4 Tetratricopeptide repeat Med26 PF08711.11 OQS04264.1 - 7.6e-09 35.5 1.0 2.1e-08 34.0 0.3 2.2 2 0 0 2 2 2 1 TFIIS helical bundle-like domain Ank_3 PF13606.6 OQS04264.1 - 1.3e-08 34.4 2.2 0.026 15.0 0.0 5.2 5 0 0 5 5 5 2 Ankyrin repeat TPR_16 PF13432.6 OQS04264.1 - 2.6e-08 34.4 4.3 0.001 19.7 0.2 4.9 4 0 0 4 4 4 1 Tetratricopeptide repeat Ank PF00023.30 OQS04264.1 - 1.2e-07 31.8 0.7 0.004 17.6 0.0 4.1 4 0 0 4 4 3 2 Ankyrin repeat Ank_5 PF13857.6 OQS04264.1 - 1.3e-06 28.6 0.1 9.5e-06 25.8 0.1 2.6 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Palm_thioest PF02089.15 OQS04264.1 - 7e-06 26.1 0.0 1.9e-05 24.6 0.0 1.6 1 0 0 1 1 1 1 Palmitoyl protein thioesterase TPR_7 PF13176.6 OQS04264.1 - 9.4e-06 25.3 10.5 0.17 12.0 0.0 6.5 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_8 PF13181.6 OQS04264.1 - 0.00012 22.0 19.9 0.54 10.6 0.3 7.4 7 0 0 7 7 7 2 Tetratricopeptide repeat Lipase_3 PF01764.25 OQS04264.1 - 0.0028 17.5 0.0 0.015 15.2 0.0 2.2 2 0 0 2 2 2 1 Lipase (class 3) PGAP1 PF07819.13 OQS04264.1 - 0.0031 17.3 0.1 0.011 15.5 0.1 1.8 1 1 0 1 1 1 1 PGAP1-like protein Lipase_2 PF01674.18 OQS04264.1 - 0.015 14.8 0.0 0.036 13.6 0.0 1.6 1 0 0 1 1 1 0 Lipase (class 2) Thioesterase PF00975.20 OQS04264.1 - 0.039 14.1 0.3 0.39 10.8 0.0 2.6 3 0 0 3 3 2 0 Thioesterase domain Abhydrolase_6 PF12697.7 OQS04264.1 - 0.05 14.2 0.0 0.17 12.4 0.0 1.9 1 1 0 1 1 1 0 Alpha/beta hydrolase family TPR_11 PF13414.6 OQS04264.1 - 0.052 13.2 1.2 5.9 6.7 0.1 4.2 3 0 0 3 3 3 0 TPR repeat TPR_17 PF13431.6 OQS04264.1 - 0.15 12.5 1.8 5.9 7.5 0.0 4.0 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_MalT PF17874.1 OQS04264.1 - 0.25 10.7 21.1 0.43 9.9 2.2 3.9 2 1 2 4 4 4 0 MalT-like TPR region DUF2072 PF09845.9 OQS04265.1 - 0.0041 17.4 1.1 1 9.6 0.5 2.1 2 0 0 2 2 2 2 Zn-ribbon containing protein WD40 PF00400.32 OQS04266.1 - 1.2e-12 48.0 10.2 0.0055 17.5 0.1 4.5 4 0 0 4 4 4 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OQS04266.1 - 0.00034 20.8 0.2 0.21 11.9 0.0 3.2 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 OQS04266.1 - 0.00072 19.5 0.0 0.036 14.0 0.0 2.4 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.16 OQS04266.1 - 0.0017 17.0 0.0 0.0031 16.1 0.0 1.3 1 0 0 1 1 1 1 Cytochrome D1 heme domain PD40 PF07676.12 OQS04266.1 - 0.013 15.4 0.1 0.58 10.2 0.0 2.5 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat DAGAT PF03982.13 OQS04267.1 - 1.7e-06 27.2 1.3 0.018 14.0 0.3 2.5 1 1 1 2 2 2 2 Diacylglycerol acyltransferase Acyltransferase PF01553.21 OQS04267.1 - 4.6e-06 26.3 0.2 0.062 12.9 0.0 3.2 2 2 0 2 2 2 2 Acyltransferase Pkinase PF00069.25 OQS04268.1 - 3e-33 115.3 0.0 3.5e-33 115.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQS04268.1 - 3.7e-31 108.3 0.0 4.7e-31 108.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase CSN8_PSD8_EIF3K PF10075.9 OQS04269.1 - 2.1e-18 66.7 0.1 3.1e-18 66.1 0.1 1.3 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family Kinesin PF00225.23 OQS04270.1 - 5.8e-49 166.8 0.1 5.8e-49 166.8 0.1 2.5 2 1 1 3 3 3 1 Kinesin motor domain Kinesin_assoc PF16183.5 OQS04270.1 - 0.064 13.4 12.2 0.25 11.4 12.2 2.1 1 1 0 1 1 1 0 Kinesin-associated RRN3 PF05327.11 OQS04271.1 - 9.8 4.6 15.1 10 4.5 15.1 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 PX PF00787.24 OQS04272.1 - 1.4e-05 25.1 0.4 2.9e-05 24.0 0.4 1.6 1 0 0 1 1 1 1 PX domain CUE PF02845.16 OQS04272.1 - 0.0019 17.9 0.0 0.0046 16.6 0.0 1.7 1 0 0 1 1 1 1 CUE domain Torus PF16131.5 OQS04273.1 - 1.3e-11 45.2 13.7 1.2e-05 25.9 0.7 3.4 1 1 1 3 3 3 3 Torus domain zf-CCCH_3 PF15663.5 OQS04273.1 - 1.6e-07 31.5 13.4 8.5e-05 22.7 1.2 2.5 1 1 1 2 2 2 2 Zinc-finger containing family zf_CCCH_4 PF18345.1 OQS04273.1 - 6.6e-07 29.2 22.7 0.012 15.6 0.6 4.8 4 1 0 4 4 4 3 Zinc finger domain zf-CCCH PF00642.24 OQS04273.1 - 6.8e-06 25.9 19.7 0.037 13.9 1.4 4.2 4 0 0 4 4 4 3 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 OQS04273.1 - 0.011 15.5 19.8 0.021 14.6 0.6 4.9 4 2 0 4 4 4 0 CCCH-type zinc finger zf-C3H1 PF10650.9 OQS04273.1 - 5.4 6.8 11.3 8.4 6.2 0.1 3.5 4 0 0 4 4 4 0 Putative zinc-finger domain UTP15_C PF09384.10 OQS04274.1 - 5.9e-37 126.6 0.0 9.2e-37 126.0 0.0 1.3 1 0 0 1 1 1 1 UTP15 C terminal WD40 PF00400.32 OQS04274.1 - 5.2e-25 87.2 13.0 2.1e-06 28.3 0.2 6.4 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OQS04274.1 - 1.5e-10 41.3 0.4 0.0018 18.5 0.0 4.3 2 2 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 OQS04274.1 - 8.7e-05 22.0 0.1 0.022 14.1 0.0 2.5 2 0 0 2 2 2 2 WD40-like domain Nup160 PF11715.8 OQS04274.1 - 0.00041 19.1 0.8 0.02 13.6 0.0 2.6 2 1 1 3 3 3 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 OQS04274.1 - 0.04 12.7 0.3 2 7.1 0.0 2.5 2 1 0 2 2 2 0 Nup133 N terminal like Cytochrom_D1 PF02239.16 OQS04274.1 - 0.062 11.8 0.7 0.16 10.5 0.1 1.9 3 0 0 3 3 3 0 Cytochrome D1 heme domain AA_permease_2 PF13520.6 OQS04275.1 - 7.7e-14 51.4 47.7 1.1e-13 50.9 47.7 1.2 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 OQS04275.1 - 8.6e-08 31.2 40.4 2.1e-07 29.9 39.4 1.9 1 1 1 2 2 2 1 Amino acid permease SMC_N PF02463.19 OQS04276.1 - 2.5e-66 223.3 39.4 9.8e-66 221.3 39.4 2.2 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 OQS04276.1 - 4.2e-25 88.3 0.1 2.9e-24 85.6 0.0 2.6 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 OQS04276.1 - 3.5e-14 53.3 0.2 2.8e-06 27.4 0.1 2.7 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 OQS04276.1 - 9.5e-05 22.1 0.0 0.00021 21.0 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_15 PF13175.6 OQS04276.1 - 0.00015 21.6 38.0 0.00015 21.6 38.0 4.4 2 2 0 2 2 2 1 AAA ATPase domain Filament PF00038.21 OQS04276.1 - 0.00029 20.5 0.7 0.00029 20.5 0.7 5.3 3 2 1 4 4 4 3 Intermediate filament protein KELK PF15796.5 OQS04276.1 - 0.0012 19.3 10.9 0.0012 19.3 10.9 9.1 3 2 7 11 11 11 1 KELK-motif containing domain of MRCK Ser/Thr protein kinase VGPC1_C PF16799.5 OQS04276.1 - 0.0045 16.9 3.7 0.028 14.4 1.1 3.4 3 0 0 3 3 3 1 C-terminal membrane-localisation domain of ion-channel, VCN1 SbcCD_C PF13558.6 OQS04276.1 - 0.063 13.5 0.0 0.25 11.6 0.0 2.0 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit DUF4140 PF13600.6 OQS04276.1 - 2.1 8.8 0.0 2.1 8.8 0.0 10.0 6 2 1 7 7 7 0 N-terminal domain of unknown function (DUF4140) Ank_2 PF12796.7 OQS04277.1 - 2.5e-22 79.2 2.8 5.4e-11 42.9 0.1 3.5 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OQS04277.1 - 6.5e-20 71.0 1.9 3.9e-07 30.2 0.0 3.6 3 0 0 3 3 3 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 OQS04277.1 - 3.9e-15 56.0 4.0 3.5e-06 27.4 0.0 4.5 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQS04277.1 - 1.7e-13 49.4 3.0 0.11 13.1 0.1 5.8 5 0 0 5 5 5 4 Ankyrin repeat PA PF02225.22 OQS04277.1 - 7.2e-12 45.2 0.1 2.1e-11 43.7 0.1 1.8 1 0 0 1 1 1 1 PA domain Isochorismatase PF00857.20 OQS04277.1 - 5.7e-09 36.4 0.0 1.2e-08 35.3 0.0 1.5 1 0 0 1 1 1 1 Isochorismatase family Ank PF00023.30 OQS04277.1 - 5.6e-08 32.9 10.5 0.28 11.7 0.1 5.7 5 0 0 5 5 5 3 Ankyrin repeat WW PF00397.26 OQS04277.1 - 9.1e-08 32.1 4.7 1.8e-07 31.1 4.7 1.5 1 0 0 1 1 1 1 WW domain DUF4484 PF14831.6 OQS04277.1 - 0.085 12.9 0.3 0.17 11.9 0.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4484) DUF1840 PF08895.11 OQS04277.1 - 4.2 7.8 5.8 1.3 9.4 1.9 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1840) Abhydrolase_1 PF00561.20 OQS04279.1 - 0.00083 19.1 0.7 0.0056 16.4 0.1 2.2 2 0 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 OQS04279.1 - 0.033 13.4 0.0 0.64 9.2 0.0 2.4 1 1 0 1 1 1 0 Serine aminopeptidase, S33 cNMP_binding PF00027.29 OQS04280.1 - 2.8e-36 123.5 0.1 1.3e-14 54.0 0.0 8.1 9 0 0 9 9 9 5 Cyclic nucleotide-binding domain LigB PF02900.18 OQS04282.1 - 2.1e-32 112.3 0.0 2.3e-32 112.2 0.0 1.0 1 0 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase Torus PF16131.5 OQS04283.1 - 1.9e-06 28.5 0.3 3.7e-06 27.6 0.3 1.5 1 1 0 1 1 1 1 Torus domain zf-CCCH PF00642.24 OQS04283.1 - 4.3e-05 23.3 3.5 4.3e-05 23.3 3.5 2.6 3 0 0 3 3 3 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 OQS04283.1 - 0.0012 18.8 2.0 0.0029 17.6 2.0 1.7 1 0 0 1 1 1 1 Zinc finger domain FYVE PF01363.21 OQS04283.1 - 0.0083 16.2 0.6 0.017 15.2 0.6 1.7 1 0 0 1 1 1 1 FYVE zinc finger zf-CCCH_4 PF18044.1 OQS04283.1 - 0.22 11.4 2.6 0.5 10.2 2.6 1.7 1 0 0 1 1 1 0 CCCH-type zinc finger LigB PF02900.18 OQS04284.1 - 2.5e-36 125.1 0.0 3e-36 124.9 0.0 1.0 1 0 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase Minor_capsid_3 PF12691.7 OQS04285.1 - 0.074 13.4 0.0 0.099 13.0 0.0 1.2 1 0 0 1 1 1 0 Minor capsid protein from bacteriophage BSD PF03909.17 OQS04287.1 - 6.9e-11 42.0 4.1 1.1e-10 41.3 2.4 2.3 2 0 0 2 2 2 1 BSD domain SAM_1 PF00536.30 OQS04288.1 - 6.4e-17 61.8 0.0 1e-16 61.1 0.0 1.3 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 OQS04288.1 - 6.2e-16 58.3 0.0 1e-15 57.6 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Tnp_zf-ribbon_2 PF13842.6 OQS04288.1 - 1.1 10.1 7.3 1.9 9.3 7.3 1.4 1 0 0 1 1 1 0 DDE_Tnp_1-like zinc-ribbon ATP-synt_10 PF05176.14 OQS04289.1 - 1.4e-28 99.8 0.1 2e-28 99.4 0.1 1.2 1 0 0 1 1 1 1 ATP10 protein DUF2423 PF10338.9 OQS04289.1 - 0.099 12.9 0.1 0.25 11.6 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2423) His_Phos_1 PF00300.22 OQS04290.1 - 7.7e-06 25.7 0.0 1.5e-05 24.8 0.0 1.5 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) NMT1 PF09084.11 OQS04290.1 - 0.0011 18.9 0.0 0.0018 18.2 0.0 1.3 1 0 0 1 1 1 1 NMT1/THI5 like Mito_carr PF00153.27 OQS04292.1 - 6.2e-62 205.6 0.2 6.9e-20 70.8 0.0 3.5 3 0 0 3 3 3 3 Mitochondrial carrier protein PX PF00787.24 OQS04292.1 - 7.4e-13 48.5 0.9 3.2e-12 46.4 0.5 2.2 2 0 0 2 2 2 1 PX domain SET PF00856.28 OQS04292.1 - 1.7e-11 44.8 0.0 1.8e-10 41.5 0.0 2.7 2 1 0 2 2 2 1 SET domain Rubis-subs-bind PF09273.11 OQS04292.1 - 9.7e-11 42.5 0.0 2.7e-10 41.0 0.0 1.8 1 0 0 1 1 1 1 Rubisco LSMT substrate-binding Tim17 PF02466.19 OQS04292.1 - 0.041 14.2 0.1 0.14 12.5 0.0 1.9 1 1 0 1 1 1 0 Tim17/Tim22/Tim23/Pmp24 family VPS13_C PF16909.5 OQS04292.1 - 0.07 12.9 0.4 1.8 8.3 0.1 2.6 2 0 0 2 2 2 0 Vacuolar-sorting-associated 13 protein C-terminal DUF4296 PF14129.6 OQS04292.1 - 0.4 11.3 13.5 0.46 11.1 1.1 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4296) LRR_6 PF13516.6 OQS04293.1 - 7.8e-13 47.4 17.3 0.018 15.0 0.1 8.6 8 0 0 8 8 8 5 Leucine Rich repeat LRR_1 PF00560.33 OQS04293.1 - 8.1e-06 25.7 7.1 8 7.4 0.1 6.5 5 1 0 5 5 5 2 Leucine Rich Repeat DUF4476 PF14771.6 OQS04293.1 - 0.0049 17.1 4.3 0.062 13.6 0.7 3.8 4 0 0 4 4 4 1 Domain of unknown function (DUF4476) LRR_4 PF12799.7 OQS04293.1 - 0.0057 17.0 18.3 0.034 14.6 0.3 5.6 4 1 3 7 7 7 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 OQS04293.1 - 1.7 8.4 25.3 0.36 10.6 3.8 5.5 3 2 1 5 5 5 0 Leucine rich repeat G6PD_C PF02781.16 OQS04294.1 - 4.7e-107 357.5 0.0 8e-107 356.7 0.0 1.3 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.22 OQS04294.1 - 1.2e-54 185.7 0.0 2.7e-54 184.5 0.0 1.7 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, NAD binding domain ArfGap PF01412.18 OQS04294.1 - 2.2e-34 118.0 0.0 5.5e-34 116.7 0.0 1.7 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf BAR_3 PF16746.5 OQS04294.1 - 1.5e-23 83.7 1.6 1.3e-21 77.4 1.6 2.4 1 1 0 1 1 1 1 BAR domain of APPL family PH PF00169.29 OQS04294.1 - 1.9e-08 34.8 0.2 5.1e-08 33.4 0.2 1.8 1 0 0 1 1 1 1 PH domain Ank_4 PF13637.6 OQS04294.1 - 2.7e-06 27.8 0.2 8.3e-06 26.3 0.2 1.9 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 OQS04294.1 - 0.00014 22.4 0.2 0.00043 20.8 0.2 1.8 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OQS04294.1 - 0.0022 18.2 0.1 0.0082 16.4 0.1 2.1 1 1 0 1 1 1 1 Ankyrin repeats (many copies) PH_9 PF15410.6 OQS04294.1 - 0.022 15.1 1.1 0.47 10.8 1.1 2.3 1 1 0 1 1 1 0 Pleckstrin homology domain Ank_3 PF13606.6 OQS04294.1 - 0.034 14.7 0.9 5.2 8.0 0.0 3.2 3 0 0 3 3 2 0 Ankyrin repeat Ank PF00023.30 OQS04294.1 - 0.04 14.4 1.9 0.068 13.6 0.2 2.3 2 0 0 2 2 1 0 Ankyrin repeat Cyto_heme_lyase PF01265.17 OQS04295.1 - 3.2e-14 53.2 0.4 3.2e-14 53.2 0.4 1.8 2 0 0 2 2 2 1 Cytochrome c/c1 heme lyase Pro-MCH PF05824.12 OQS04296.1 - 0.1 12.6 0.3 0.26 11.2 0.3 1.7 1 0 0 1 1 1 0 Pro-melanin-concentrating hormone (Pro-MCH) CemA PF03040.14 OQS04296.1 - 1.5 8.7 5.4 0.61 10.0 0.4 2.4 1 1 0 2 2 2 0 CemA family Myosin_head PF00063.21 OQS04297.1 - 4.1e-68 230.2 0.0 6.2e-68 229.6 0.0 1.3 1 0 0 1 1 1 1 Myosin head (motor domain) Ank_4 PF13637.6 OQS04297.1 - 1.3e-18 67.1 1.8 9.5e-06 26.1 0.2 5.0 2 2 3 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQS04297.1 - 6.8e-17 59.8 1.3 0.0011 19.2 0.1 5.9 5 0 0 5 5 5 3 Ankyrin repeat Ank_5 PF13857.6 OQS04297.1 - 1.9e-16 59.9 2.0 7e-05 23.0 0.0 4.3 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 OQS04297.1 - 3e-16 59.8 0.1 3e-07 30.9 0.0 3.5 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.30 OQS04297.1 - 7.2e-16 57.8 1.3 0.0014 19.0 0.0 5.5 5 0 0 5 5 5 4 Ankyrin repeat FYVE PF01363.21 OQS04297.1 - 2.5e-10 40.3 8.7 2.5e-10 40.3 8.7 2.3 3 0 0 3 3 3 1 FYVE zinc finger IQ PF00612.27 OQS04297.1 - 1.8e-06 27.2 40.7 0.0076 16.0 2.0 6.1 6 0 0 6 6 6 5 IQ calmodulin-binding motif Takusan PF04822.13 OQS04297.1 - 0.14 12.1 5.4 0.32 10.9 5.4 1.5 1 0 0 1 1 1 0 Takusan NIF PF03031.18 OQS04298.1 - 1.7e-51 174.1 0.9 3.1e-51 173.2 0.9 1.4 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase HAD PF12710.7 OQS04298.1 - 0.00041 20.8 0.1 0.0032 17.9 0.0 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cyt-b5 PF00173.28 OQS04299.1 - 2.9e-06 27.3 0.0 3.9e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain TPR_12 PF13424.6 OQS04300.1 - 9.2e-14 51.5 10.3 4.9e-05 23.5 0.3 5.7 3 1 2 6 6 6 5 Tetratricopeptide repeat TPR_2 PF07719.17 OQS04300.1 - 0.0002 21.2 4.5 0.68 10.2 0.4 5.3 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_19 PF14559.6 OQS04300.1 - 0.0028 18.1 10.7 1.5 9.4 0.1 4.6 3 1 2 5 5 5 2 Tetratricopeptide repeat TPR_10 PF13374.6 OQS04300.1 - 0.0036 17.1 7.0 4.2 7.4 0.0 5.3 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_6 PF13174.6 OQS04300.1 - 0.02 15.5 1.2 12 6.8 0.0 5.0 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_16 PF13432.6 OQS04300.1 - 1.2 9.9 7.6 24 5.7 0.3 4.5 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_8 PF13181.6 OQS04300.1 - 3.3 8.1 7.5 8.6 6.9 0.4 4.4 5 0 0 5 5 5 0 Tetratricopeptide repeat Ank_5 PF13857.6 OQS04301.1 - 0.00085 19.6 0.4 0.098 13.0 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 OQS04301.1 - 0.0048 17.4 2.2 0.035 14.7 0.5 2.3 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 OQS04301.1 - 0.1 13.2 0.4 0.22 12.1 0.3 1.5 1 1 0 1 1 1 0 Ankyrin repeats (3 copies) DUF5049 PF16468.5 OQS04301.1 - 0.14 12.1 0.0 1.2 9.1 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF5049) Mito_carr PF00153.27 OQS04303.1 - 3.3e-59 196.8 5.4 4.9e-23 80.9 0.1 3.0 2 1 1 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 OQS04303.1 - 0.0039 16.4 2.2 0.053 12.7 0.5 2.4 1 1 1 2 2 2 2 Gammaproteobacterial serine protease EamA PF00892.20 OQS04304.1 - 1.4e-17 64.1 34.9 1.8e-13 50.9 13.1 2.2 2 1 0 2 2 2 2 EamA-like transporter family TPT PF03151.16 OQS04304.1 - 0.00022 20.7 5.3 0.00022 20.7 5.3 2.1 1 1 1 2 2 2 1 Triose-phosphate Transporter family Multi_Drug_Res PF00893.19 OQS04304.1 - 0.031 14.9 13.0 0.2 12.4 3.7 3.1 2 2 0 2 2 2 0 Small Multidrug Resistance protein Cys_Met_Meta_PP PF01053.20 OQS04305.1 - 5e-134 446.6 0.0 6e-134 446.4 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 OQS04305.1 - 1.8e-06 27.2 0.0 5e-06 25.7 0.0 1.6 2 0 0 2 2 2 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 OQS04305.1 - 0.00016 21.2 0.0 0.00027 20.4 0.0 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_1_2 PF00155.21 OQS04305.1 - 0.0061 15.8 0.0 0.0096 15.1 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II GDC-P PF02347.16 OQS04305.1 - 0.0093 14.8 0.0 0.015 14.2 0.0 1.2 1 0 0 1 1 1 1 Glycine cleavage system P-protein Fz PF01392.22 OQS04306.1 - 0.005 17.5 8.5 0.0076 16.9 8.5 1.3 1 0 0 1 1 1 1 Fz domain PPR_2 PF13041.6 OQS04308.1 - 0.0059 16.8 0.0 55 4.1 0.0 5.0 5 0 0 5 5 5 0 PPR repeat family TPR_2 PF07719.17 OQS04308.1 - 0.037 14.1 1.1 0.59 10.4 0.6 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat PPR PF01535.20 OQS04308.1 - 0.086 13.1 0.2 1.5e+02 3.0 0.0 4.4 4 0 0 4 4 4 0 PPR repeat DUF5485 PF17586.2 OQS04308.1 - 0.22 11.9 1.1 30 5.0 0.0 3.5 3 0 0 3 3 3 0 Family of unknown function (DUF5485) TPR_8 PF13181.6 OQS04308.1 - 0.58 10.5 2.1 3.4 8.1 0.5 3.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.28 OQS04308.1 - 0.87 9.5 4.1 2.5 8.1 0.4 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat Kinesin PF00225.23 OQS04309.1 - 1.4e-110 369.3 1.8 1.4e-110 369.3 1.8 2.5 3 0 0 3 3 3 1 Kinesin motor domain Microtub_bd PF16796.5 OQS04309.1 - 8.5e-26 90.7 3.6 9.9e-26 90.5 0.0 3.1 3 1 1 4 4 4 1 Microtubule binding CENP-F_leu_zip PF10473.9 OQS04309.1 - 0.0012 18.9 18.9 0.0012 18.9 18.9 7.9 2 1 3 7 7 7 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 tRNA-synt_1b PF00579.25 OQS04310.1 - 4.9e-21 75.3 0.1 1.9e-20 73.3 0.0 2.0 2 1 0 2 2 2 1 tRNA synthetases class I (W and Y) WHEP-TRS PF00458.20 OQS04310.1 - 3.8e-14 52.6 4.7 3.8e-14 52.6 4.7 2.5 2 0 0 2 2 2 1 WHEP-TRS domain RB_A PF01858.17 OQS04311.1 - 2.8e-54 183.9 0.6 6.9e-54 182.7 0.0 2.0 3 0 0 3 3 3 1 Retinoblastoma-associated protein A domain RB_B PF01857.20 OQS04311.1 - 4.5e-33 114.1 0.5 2.1e-32 111.9 0.5 2.3 1 0 0 1 1 1 1 Retinoblastoma-associated protein B domain DUF3452 PF11934.8 OQS04311.1 - 3.4e-15 55.8 3.9 3.5e-12 46.1 1.2 3.7 3 1 0 3 3 3 2 Domain of unknown function (DUF3452) Ank_2 PF12796.7 OQS04311.1 - 3.5e-09 37.1 8.3 7.5e-06 26.5 0.7 3.1 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQS04311.1 - 1.1e-07 32.2 9.7 0.00026 21.5 0.3 4.6 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQS04311.1 - 0.00011 22.4 3.2 19 6.2 0.0 6.1 4 1 1 5 5 5 1 Ankyrin repeat Rb_C PF08934.10 OQS04311.1 - 0.00012 22.0 0.0 0.00027 20.8 0.0 1.5 1 0 0 1 1 1 1 Rb C-terminal domain Ank_5 PF13857.6 OQS04311.1 - 0.007 16.7 5.1 8.9 6.8 0.1 4.3 2 1 2 4 4 4 1 Ankyrin repeats (many copies) Ank PF00023.30 OQS04311.1 - 1.7 9.2 5.3 85 3.9 0.4 4.6 1 1 2 3 3 3 0 Ankyrin repeat Ank_2 PF12796.7 OQS04312.1 - 8.2e-49 164.1 30.6 1.9e-10 41.2 0.1 5.2 1 1 6 7 7 7 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQS04312.1 - 4.9e-30 103.5 15.3 1e-06 29.2 0.1 7.6 4 1 3 8 8 8 7 Ankyrin repeats (many copies) Ank_5 PF13857.6 OQS04312.1 - 1.2e-26 92.4 17.1 0.0017 18.7 0.1 10.1 2 1 9 11 11 11 9 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQS04312.1 - 1.5e-17 61.9 10.8 0.15 12.7 0.0 10.4 9 2 2 11 11 11 4 Ankyrin repeat Ank PF00023.30 OQS04312.1 - 1.2e-06 28.7 7.3 1.8 9.1 0.0 8.5 4 2 4 8 8 8 1 Ankyrin repeat DUF5049 PF16468.5 OQS04312.1 - 2.5e-05 24.1 3.4 33 4.5 0.1 7.4 6 1 3 9 9 9 0 Domain of unknown function (DUF5049) DUF3447 PF11929.8 OQS04312.1 - 7.2e-05 22.7 8.8 0.0047 16.9 0.4 4.8 3 1 3 6 6 6 1 Domain of unknown function (DUF3447) DUF411 PF04214.13 OQS04312.1 - 0.026 14.5 0.3 1.9 8.5 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function, DUF ENTH PF01417.20 OQS04312.1 - 0.063 13.3 0.5 13 5.8 0.0 3.8 3 1 1 5 5 5 0 ENTH domain Pkinase PF00069.25 OQS04313.1 - 8.6e-58 195.8 0.0 2.7e-57 194.1 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQS04313.1 - 1.4e-28 99.9 0.0 8.6e-25 87.5 0.0 3.0 2 1 1 3 3 3 2 Protein tyrosine kinase PPI_Ypi1 PF07491.11 OQS04313.1 - 4.3e-17 61.7 0.9 1e-16 60.5 0.9 1.6 1 0 0 1 1 1 1 Protein phosphatase inhibitor Haspin_kinase PF12330.8 OQS04313.1 - 1.6e-05 24.0 0.3 2.7e-05 23.3 0.3 1.3 1 0 0 1 1 1 1 Haspin like kinase domain RIO1 PF01163.22 OQS04313.1 - 0.013 15.1 0.1 0.028 14.0 0.1 1.5 1 0 0 1 1 1 0 RIO1 family APH PF01636.23 OQS04313.1 - 0.033 14.1 0.5 0.092 12.6 0.4 1.8 1 1 0 1 1 1 0 Phosphotransferase enzyme family Kinase-like PF14531.6 OQS04313.1 - 0.05 12.9 0.0 0.091 12.1 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Piwi PF02171.17 OQS04315.1 - 2e-97 326.1 0.0 3.1e-97 325.5 0.0 1.3 1 0 0 1 1 1 1 Piwi domain PAZ PF02170.22 OQS04315.1 - 6.6e-19 68.1 0.0 1.1e-18 67.4 0.0 1.3 1 0 0 1 1 1 1 PAZ domain ArgoL1 PF08699.10 OQS04315.1 - 7.3e-19 67.2 0.0 1.8e-18 65.9 0.0 1.8 1 0 0 1 1 1 1 Argonaute linker 1 domain ArgoN PF16486.5 OQS04315.1 - 4.8e-15 56.4 0.0 1.2e-14 55.1 0.0 1.7 1 0 0 1 1 1 1 N-terminal domain of argonaute ArgoL2 PF16488.5 OQS04315.1 - 2.8e-09 37.2 0.0 1.1e-08 35.2 0.0 2.1 2 0 0 2 2 2 1 Argonaute linker 2 domain ArgoMid PF16487.5 OQS04315.1 - 4.5e-08 33.2 0.0 4.5e-07 30.0 0.0 2.6 3 0 0 3 3 3 1 Mid domain of argonaute PH PF00169.29 OQS04316.1 - 0.0053 17.3 0.0 0.037 14.5 0.0 2.3 2 1 0 2 2 2 1 PH domain AvrM-A PF18241.1 OQS04316.1 - 0.043 14.2 4.3 0.063 13.7 4.3 1.2 1 0 0 1 1 1 0 Flax-rust effector AvrM-A PBP_sp32 PF07222.12 OQS04316.1 - 0.35 10.3 5.1 0.46 9.9 5.1 1.1 1 0 0 1 1 1 0 Proacrosin binding protein sp32 DUF2458 PF10454.9 OQS04316.1 - 0.43 10.2 9.8 0.99 9.0 9.8 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2458) 2_5_RNA_ligase2 PF13563.6 OQS04317.1 - 3.2e-25 88.8 0.4 3.8e-25 88.6 0.4 1.1 1 0 0 1 1 1 1 2'-5' RNA ligase superfamily LigT_PEase PF02834.16 OQS04317.1 - 3.9e-07 30.2 0.1 0.00047 20.3 0.0 2.2 2 0 0 2 2 2 2 LigT like Phosphoesterase TIP49 PF06068.13 OQS04318.1 - 8e-72 242.3 0.3 1.3e-71 241.6 0.0 1.5 2 0 0 2 2 2 1 TIP49 P-loop domain TIP49_C PF17856.1 OQS04318.1 - 2.6e-25 88.3 0.9 5.4e-25 87.3 0.9 1.6 1 0 0 1 1 1 1 TIP49 AAA-lid domain Isochorismatase PF00857.20 OQS04318.1 - 1.2e-06 28.8 0.0 9.2e-05 22.7 0.0 3.0 1 1 1 2 2 2 1 Isochorismatase family AAA_22 PF13401.6 OQS04318.1 - 0.012 15.9 0.0 0.03 14.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain TFIID_20kDa PF03847.13 OQS04318.1 - 0.23 12.0 5.6 4.1 8.0 0.1 3.3 4 0 0 4 4 4 0 Transcription initiation factor TFIID subunit A C2 PF00168.30 OQS04319.1 - 2.3e-19 69.6 0.0 5.5e-19 68.4 0.0 1.6 1 0 0 1 1 1 1 C2 domain CEP76-C2 PF15627.6 OQS04319.1 - 0.009 15.6 0.1 0.023 14.3 0.1 1.7 1 1 0 1 1 1 1 CEP76 C2 domain ubiquitin PF00240.23 OQS04320.1 - 0.11 12.3 0.0 0.26 11.0 0.0 1.6 1 0 0 1 1 1 0 Ubiquitin family Dak1 PF02733.17 OQS04323.1 - 1.3e-105 352.8 1.7 2.8e-105 351.6 2.0 1.4 2 0 0 2 2 2 1 Dak1 domain Dak2 PF02734.17 OQS04323.1 - 7.5e-44 149.7 0.6 1.3e-43 148.9 0.6 1.4 1 0 0 1 1 1 1 DAK2 domain PAP_fibrillin PF04755.12 OQS04324.1 - 0.074 13.0 0.6 0.13 12.2 0.6 1.5 1 0 0 1 1 1 0 PAP_fibrillin Mrr_cat PF04471.12 OQS04327.1 - 3.3e-11 43.2 0.0 4.1e-11 42.9 0.0 1.1 1 0 0 1 1 1 1 Restriction endonuclease DUF2034 PF10356.9 OQS04327.1 - 9.2e-10 38.2 0.0 1.3e-05 24.8 0.0 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF2034) ThiF PF00899.21 OQS04328.1 - 1.9e-48 164.9 0.0 4.4e-48 163.8 0.0 1.5 2 0 0 2 2 2 1 ThiF family ATG7_N PF16420.5 OQS04328.1 - 2.8e-42 145.4 0.2 3.6e-42 145.0 0.2 1.2 1 0 0 1 1 1 1 Ubiquitin-like modifier-activating enzyme ATG7 N-terminus Shikimate_DH PF01488.20 OQS04328.1 - 0.00041 20.4 0.0 0.074 13.1 0.0 2.3 2 0 0 2 2 2 2 Shikimate / quinate 5-dehydrogenase Ras PF00071.22 OQS04329.1 - 4e-41 140.3 0.1 5.7e-40 136.6 0.1 2.0 1 1 0 1 1 1 1 Ras family Roc PF08477.13 OQS04329.1 - 1.6e-26 92.9 0.0 7.9e-25 87.4 0.0 2.2 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OQS04329.1 - 1.8e-10 40.5 0.0 4.7e-10 39.2 0.0 1.6 1 1 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 OQS04329.1 - 4e-05 23.3 0.1 5.9e-05 22.7 0.1 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 OQS04329.1 - 8.9e-05 22.6 0.0 0.00015 21.8 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Ploopntkinase3 PF18751.1 OQS04329.1 - 0.0048 16.8 0.0 0.0079 16.1 0.0 1.3 1 0 0 1 1 1 1 P-loop Nucleotide Kinase3 MCM PF00493.23 OQS04329.1 - 0.01 15.0 0.0 0.019 14.1 0.0 1.4 1 0 0 1 1 1 0 MCM P-loop domain cobW PF02492.19 OQS04329.1 - 0.01 15.4 0.0 1 8.9 0.0 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_22 PF13401.6 OQS04329.1 - 0.011 16.1 0.0 0.019 15.2 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_5 PF07728.14 OQS04329.1 - 0.022 14.7 0.0 0.045 13.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) SRPRB PF09439.10 OQS04329.1 - 0.044 13.2 0.0 0.17 11.3 0.0 1.9 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_24 PF13479.6 OQS04329.1 - 0.045 13.5 0.0 0.074 12.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 OQS04329.1 - 0.058 13.8 0.1 0.11 12.9 0.1 1.7 1 1 0 1 1 1 0 AAA ATPase domain TniB PF05621.11 OQS04329.1 - 0.063 12.7 0.0 0.14 11.6 0.0 1.6 1 0 0 1 1 1 0 Bacterial TniB protein PAN_1 PF00024.26 OQS04330.1 - 1.5e-16 60.1 18.4 9.4e-08 31.9 4.0 3.3 1 1 2 3 3 3 3 PAN domain PAN_4 PF14295.6 OQS04330.1 - 4.7e-13 48.8 24.6 1.7e-05 24.6 3.0 3.5 3 0 0 3 3 3 3 PAN domain PAN_3 PF08277.12 OQS04330.1 - 3.5 7.5 22.2 2.9 7.8 3.4 3.5 3 0 0 3 3 3 0 PAN-like domain MFS_2 PF13347.6 OQS04331.1 - 3.4e-10 39.1 19.6 1.2e-08 33.9 9.1 2.4 2 0 0 2 2 2 2 MFS/sugar transport protein Popeye PF04831.13 OQS04331.1 - 0.77 9.9 7.7 0.085 13.0 0.9 2.4 2 0 0 2 2 2 0 Popeye protein conserved region Bcr-Abl_Oligo PF09036.10 OQS04331.1 - 2.8 8.0 6.4 1 9.4 0.0 2.7 2 1 0 2 2 2 0 Bcr-Abl oncoprotein oligomerisation domain DHHC PF01529.20 OQS04332.1 - 5.5e-27 94.5 13.0 5.5e-27 94.5 13.0 1.6 2 0 0 2 2 2 1 DHHC palmitoyltransferase FKBP_C PF00254.28 OQS04333.1 - 2.6e-20 72.5 0.0 6.9e-20 71.2 0.0 1.8 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase PUB PF09409.10 OQS04334.1 - 1.3e-14 53.8 0.0 2.6e-14 52.9 0.0 1.5 1 0 0 1 1 1 1 PUB domain Pex14_N PF04695.13 OQS04334.1 - 8.9e-11 42.7 2.9 8.9e-11 42.7 2.9 2.7 2 1 0 2 2 2 1 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF5572 PF17733.1 OQS04334.1 - 4.6e-10 39.2 0.2 1.5e-09 37.5 0.2 2.0 1 0 0 1 1 1 1 Family of unknown function (DUF5572) GET2 PF08690.10 OQS04334.1 - 0.00087 19.1 0.8 0.00087 19.1 0.8 2.3 2 0 0 2 2 2 1 GET complex subunit GET2 MCC-bdg_PDZ PF10506.9 OQS04334.1 - 0.077 13.0 3.6 5.3 7.1 0.2 3.5 3 0 0 3 3 3 0 PDZ domain of MCC-2 bdg protein for Usher syndrome DivIC PF04977.15 OQS04334.1 - 0.26 11.1 3.0 0.62 9.9 1.4 2.5 2 1 0 2 2 2 0 Septum formation initiator DNA_topoisoIV PF00521.20 OQS04334.1 - 0.28 10.0 9.4 0.028 13.3 3.9 2.0 2 0 0 2 2 2 0 DNA gyrase/topoisomerase IV, subunit A THOC7 PF05615.13 OQS04334.1 - 0.56 10.5 10.5 0.098 12.9 6.1 2.0 2 0 0 2 2 2 0 Tho complex subunit 7 DUF724 PF05266.14 OQS04334.1 - 0.7 9.7 9.5 1.8 8.3 9.5 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF724) Atg14 PF10186.9 OQS04334.1 - 1.8 7.6 7.2 3.5 6.6 7.2 1.6 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Spc24 PF08286.11 OQS04334.1 - 2.2 8.6 8.7 15 5.9 8.1 2.7 1 1 0 1 1 1 0 Spc24 subunit of Ndc80 TMPIT PF07851.13 OQS04334.1 - 2.3 7.4 7.5 4.1 6.6 7.5 1.4 1 0 0 1 1 1 0 TMPIT-like protein EF-G-binding_N PF07299.11 OQS04334.1 - 2.8 8.5 8.5 5.5 7.6 1.6 3.0 2 0 0 2 2 2 0 Elongation factor G-binding protein, N-terminal MMR_HSR1 PF01926.23 OQS04335.1 - 4.8e-14 52.4 0.1 1e-11 44.9 0.0 2.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 OQS04335.1 - 1.4e-06 27.9 0.1 0.0016 18.0 0.0 2.5 2 0 0 2 2 2 2 Ferrous iron transport protein B RsgA_GTPase PF03193.16 OQS04335.1 - 1.1e-05 25.4 0.2 0.02 14.8 0.0 2.6 2 0 0 2 2 2 2 RsgA GTPase AIG1 PF04548.16 OQS04335.1 - 0.0075 15.6 0.0 0.021 14.1 0.0 1.7 1 0 0 1 1 1 1 AIG1 family Sporozoite_P67 PF05642.11 OQS04335.1 - 0.018 13.2 0.3 0.024 12.8 0.3 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen MeaB PF03308.16 OQS04335.1 - 0.021 13.8 0.0 0.043 12.8 0.0 1.4 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB CDC45 PF02724.14 OQS04335.1 - 0.2 9.9 5.8 0.34 9.2 5.8 1.3 1 0 0 1 1 1 0 CDC45-like protein FAM176 PF14851.6 OQS04335.1 - 2.3 7.9 6.7 6.1 6.5 6.7 1.7 1 0 0 1 1 1 0 FAM176 family Hydrolase_4 PF12146.8 OQS04336.1 - 1.7e-16 60.3 0.0 2.2e-16 59.9 0.0 1.1 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 OQS04336.1 - 4.2e-12 46.2 0.0 7.5e-12 45.4 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 OQS04336.1 - 6.1e-11 43.3 0.0 7.2e-11 43.1 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family PAF-AH_p_II PF03403.13 OQS04336.1 - 0.13 10.8 0.0 0.19 10.2 0.0 1.4 1 0 0 1 1 1 0 Platelet-activating factor acetylhydrolase, isoform II PH_3 PF14593.6 OQS04337.1 - 1.8e-08 34.4 0.1 2.4e-08 34.0 0.1 1.1 1 0 0 1 1 1 1 PH domain Bul1_N PF04425.12 OQS04337.1 - 0.015 14.1 0.0 0.017 13.9 0.0 1.0 1 0 0 1 1 1 0 Bul1 N terminus Ammonium_transp PF00909.21 OQS04338.1 - 2.8e-116 388.5 29.5 3.4e-116 388.2 29.5 1.1 1 0 0 1 1 1 1 Ammonium Transporter Family ABC_tran PF00005.27 OQS04339.1 - 1e-38 132.9 0.0 1.5e-22 80.6 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 OQS04339.1 - 2.7e-36 125.6 28.4 6.9e-22 78.4 10.4 2.6 2 1 1 3 3 3 2 ABC transporter transmembrane region AAA_29 PF13555.6 OQS04339.1 - 5.9e-08 32.3 0.1 0.0047 16.6 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 OQS04339.1 - 7.7e-08 32.9 1.2 0.0018 18.7 0.0 3.0 4 0 0 4 4 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 OQS04339.1 - 9.1e-08 32.2 0.1 0.00041 20.3 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 OQS04339.1 - 1.9e-06 27.9 0.9 0.042 13.9 0.1 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_22 PF13401.6 OQS04339.1 - 1.1e-05 25.7 1.2 0.07 13.4 0.0 3.7 3 1 0 3 3 3 2 AAA domain Dynamin_N PF00350.23 OQS04339.1 - 5.7e-05 23.2 0.6 0.37 10.8 0.0 2.8 3 0 0 3 3 2 2 Dynamin family AAA_21 PF13304.6 OQS04339.1 - 9.3e-05 22.4 0.2 0.19 11.5 0.0 2.3 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system cobW PF02492.19 OQS04339.1 - 0.00015 21.4 0.4 0.3 10.6 0.0 2.4 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain DUF87 PF01935.17 OQS04339.1 - 0.00018 21.7 0.7 0.18 11.8 0.0 2.3 2 0 0 2 2 2 2 Helicase HerA, central domain SMC_N PF02463.19 OQS04339.1 - 0.00021 20.8 6.2 0.34 10.3 0.1 3.6 4 0 0 4 4 3 2 RecF/RecN/SMC N terminal domain AAA_30 PF13604.6 OQS04339.1 - 0.0004 20.2 0.1 0.072 12.8 0.0 2.7 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 OQS04339.1 - 0.00079 19.4 0.2 0.04 13.8 0.0 2.9 2 0 0 2 2 2 1 NACHT domain AAA_24 PF13479.6 OQS04339.1 - 0.001 18.8 0.0 1.2 8.8 0.0 2.3 2 0 0 2 2 2 2 AAA domain T2SSE PF00437.20 OQS04339.1 - 0.0012 18.0 0.1 0.029 13.4 0.0 2.3 2 0 0 2 2 2 1 Type II/IV secretion system protein ATP_bind_1 PF03029.17 OQS04339.1 - 0.002 18.0 2.9 0.63 9.8 0.0 3.7 4 0 0 4 4 3 1 Conserved hypothetical ATP binding protein GTP_EFTU PF00009.27 OQS04339.1 - 0.0036 16.9 0.2 1.6 8.2 0.1 2.3 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain NB-ARC PF00931.22 OQS04339.1 - 0.004 16.4 0.1 0.087 12.0 0.0 2.4 2 0 0 2 2 2 1 NB-ARC domain DUF815 PF05673.13 OQS04339.1 - 0.0066 15.6 0.1 0.32 10.1 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_23 PF13476.6 OQS04339.1 - 0.0069 16.9 5.0 0.11 12.9 0.0 2.6 3 0 0 3 3 2 1 AAA domain TrwB_AAD_bind PF10412.9 OQS04339.1 - 0.012 14.6 0.1 3 6.7 0.0 2.6 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain Viral_helicase1 PF01443.18 OQS04339.1 - 0.015 15.0 0.2 0.41 10.3 0.0 2.4 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase FtsK_SpoIIIE PF01580.18 OQS04339.1 - 0.017 14.5 0.3 5.6 6.2 0.0 2.6 3 0 0 3 3 2 0 FtsK/SpoIIIE family AAA_7 PF12775.7 OQS04339.1 - 0.018 14.6 0.5 4.5 6.7 0.0 2.8 3 0 0 3 3 2 0 P-loop containing dynein motor region AAA_33 PF13671.6 OQS04339.1 - 0.021 15.0 0.1 1.3 9.2 0.0 2.7 2 0 0 2 2 2 0 AAA domain MeaB PF03308.16 OQS04339.1 - 0.021 13.8 0.0 3.7 6.4 0.0 2.3 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_25 PF13481.6 OQS04339.1 - 0.027 14.1 0.1 0.11 12.1 0.0 1.9 2 0 0 2 2 2 0 AAA domain Roc PF08477.13 OQS04339.1 - 0.038 14.2 0.1 9.6 6.5 0.1 2.5 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase RNA_helicase PF00910.22 OQS04339.1 - 0.083 13.3 0.5 2 8.8 0.0 2.9 3 0 0 3 3 3 0 RNA helicase AAA_18 PF13238.6 OQS04339.1 - 0.1 13.1 2.2 11 6.6 0.0 3.0 3 0 0 3 3 2 0 AAA domain AAA PF00004.29 OQS04339.1 - 0.1 13.0 0.0 5.1 7.5 0.0 2.8 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.6 OQS04339.1 - 0.11 12.8 0.2 3.3 8.1 0.1 2.7 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 OQS04339.1 - 0.13 12.5 1.0 6.9 6.9 0.1 2.6 2 0 0 2 2 2 0 AAA domain ATPase_2 PF01637.18 OQS04339.1 - 0.14 12.1 0.0 0.96 9.3 0.0 2.1 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea AAA_15 PF13175.6 OQS04339.1 - 0.16 11.6 0.3 7.4 6.2 0.1 2.2 2 0 0 2 2 2 0 AAA ATPase domain Cytidylate_kin PF02224.18 OQS04339.1 - 0.17 11.6 0.1 0.59 9.8 0.0 2.0 2 0 0 2 2 2 0 Cytidylate kinase Ploopntkinase3 PF18751.1 OQS04339.1 - 0.18 11.7 0.0 6.7 6.6 0.0 2.4 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 Aldo_ket_red PF00248.21 OQS04340.1 - 2.7e-75 253.3 0.0 3.1e-75 253.1 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family AAA PF00004.29 OQS04341.1 - 1.8e-07 31.6 0.0 3.8e-07 30.6 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 OQS04341.1 - 2.6e-06 27.9 0.0 8.8e-06 26.2 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain NTPase_1 PF03266.15 OQS04341.1 - 8.2e-06 25.8 0.1 0.05 13.5 0.0 2.4 2 0 0 2 2 2 2 NTPase AAA_7 PF12775.7 OQS04341.1 - 5.9e-05 22.6 0.0 0.00011 21.8 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_5 PF07728.14 OQS04341.1 - 0.00034 20.6 0.0 0.0014 18.6 0.0 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Rad17 PF03215.15 OQS04341.1 - 0.00044 20.2 0.0 0.001 19.0 0.0 1.5 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_18 PF13238.6 OQS04341.1 - 0.00059 20.4 0.0 0.0011 19.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 OQS04341.1 - 0.00061 20.1 0.0 0.0021 18.3 0.0 2.0 1 1 0 1 1 1 1 AAA domain NACHT PF05729.12 OQS04341.1 - 0.00071 19.5 0.0 0.0013 18.7 0.0 1.4 1 0 0 1 1 1 1 NACHT domain Viral_helicase1 PF01443.18 OQS04341.1 - 0.00077 19.3 0.0 0.0012 18.6 0.0 1.3 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA_33 PF13671.6 OQS04341.1 - 0.0015 18.7 0.0 0.0041 17.3 0.0 1.7 2 0 0 2 2 1 1 AAA domain AAA_30 PF13604.6 OQS04341.1 - 0.0032 17.2 0.0 0.0081 15.9 0.0 1.6 1 1 0 1 1 1 1 AAA domain TniB PF05621.11 OQS04341.1 - 0.0041 16.6 0.0 0.4 10.1 0.0 2.2 2 0 0 2 2 2 1 Bacterial TniB protein RNA_helicase PF00910.22 OQS04341.1 - 0.0057 17.0 0.0 0.015 15.7 0.0 1.8 1 1 0 1 1 1 1 RNA helicase ABC_tran PF00005.27 OQS04341.1 - 0.0089 16.5 0.0 0.11 13.1 0.0 2.4 1 1 0 2 2 2 1 ABC transporter AAA_14 PF13173.6 OQS04341.1 - 0.011 15.8 0.0 0.027 14.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 OQS04341.1 - 0.011 15.7 0.0 0.028 14.4 0.0 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_19 PF13245.6 OQS04341.1 - 0.012 15.9 0.0 0.039 14.3 0.0 1.8 2 0 0 2 2 1 0 AAA domain Mg_chelatase PF01078.21 OQS04341.1 - 0.019 14.4 0.0 0.033 13.6 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Zeta_toxin PF06414.12 OQS04341.1 - 0.02 14.2 0.0 0.036 13.3 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_28 PF13521.6 OQS04341.1 - 0.024 14.9 0.0 0.1 12.9 0.0 1.9 2 0 0 2 2 2 0 AAA domain MCM PF00493.23 OQS04341.1 - 0.031 13.4 0.0 0.054 12.6 0.0 1.3 1 0 0 1 1 1 0 MCM P-loop domain T2SSE PF00437.20 OQS04341.1 - 0.034 13.2 0.0 0.051 12.6 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein RuvB_N PF05496.12 OQS04341.1 - 0.038 13.8 0.0 0.26 11.0 0.0 2.2 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain G-alpha PF00503.20 OQS04341.1 - 0.056 12.6 0.0 0.09 11.9 0.0 1.2 1 0 0 1 1 1 0 G-protein alpha subunit PduV-EutP PF10662.9 OQS04341.1 - 0.069 12.9 0.0 0.14 11.9 0.0 1.5 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_11 PF13086.6 OQS04341.1 - 0.069 12.9 0.0 0.21 11.4 0.0 1.7 1 1 1 2 2 2 0 AAA domain NB-ARC PF00931.22 OQS04341.1 - 0.075 12.2 0.0 0.12 11.5 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain AAA_24 PF13479.6 OQS04341.1 - 0.079 12.7 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain ResIII PF04851.15 OQS04341.1 - 0.079 12.9 0.0 0.17 11.9 0.0 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit CbiA PF01656.23 OQS04341.1 - 0.082 13.0 0.0 0.34 11.0 0.0 2.0 2 1 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_2 PF07724.14 OQS04341.1 - 0.084 13.0 0.0 0.14 12.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) DUF815 PF05673.13 OQS04341.1 - 0.11 11.6 0.0 0.19 10.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) TIP49 PF06068.13 OQS04341.1 - 0.12 11.5 0.0 0.19 10.9 0.0 1.2 1 0 0 1 1 1 0 TIP49 P-loop domain IstB_IS21 PF01695.17 OQS04341.1 - 0.13 11.9 0.0 0.56 9.9 0.0 1.9 2 0 0 2 2 2 0 IstB-like ATP binding protein KTI12 PF08433.10 OQS04341.1 - 0.15 11.5 0.0 0.45 9.9 0.0 1.7 2 0 0 2 2 2 0 Chromatin associated protein KTI12 Sigma54_activat PF00158.26 OQS04341.1 - 0.15 11.7 0.0 0.3 10.8 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain Aldo_ket_red PF00248.21 OQS04342.1 - 1.7e-74 250.6 0.0 5.7e-74 249.0 0.0 1.8 2 0 0 2 2 2 1 Aldo/keto reductase family DIMCO_N PF16844.5 OQS04342.1 - 0.081 13.3 5.5 0.087 13.2 3.5 2.1 2 0 0 2 2 2 0 Dinitrogenase iron-molybdenum cofactor, N-terminal TssC PF17541.2 OQS04342.1 - 0.1 11.4 2.8 0.16 10.7 2.8 1.3 1 0 0 1 1 1 0 Type VI secretion system, TssC, VipB MFS_1 PF07690.16 OQS04343.1 - 6.5e-16 58.2 41.7 6.3e-08 31.9 22.9 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily Nodulin-like PF06813.13 OQS04343.1 - 8.9e-11 41.8 8.3 8.9e-11 41.8 8.3 1.9 2 0 0 2 2 2 1 Nodulin-like AAA PF00004.29 OQS04344.1 - 3.9e-07 30.6 0.0 1.2e-06 29.0 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Homeodomain PF00046.29 OQS04344.1 - 4.8e-06 26.3 7.1 0.037 13.9 0.2 3.1 2 1 0 2 2 2 2 Homeodomain AAA_16 PF13191.6 OQS04344.1 - 2.9e-05 24.5 0.0 0.00011 22.6 0.0 2.0 2 0 0 2 2 1 1 AAA ATPase domain NTPase_1 PF03266.15 OQS04344.1 - 3.5e-05 23.8 0.2 0.14 12.1 0.0 3.0 3 0 0 3 3 2 2 NTPase Rad17 PF03215.15 OQS04344.1 - 9.5e-05 22.4 0.0 0.00034 20.6 0.0 1.9 2 0 0 2 2 1 1 Rad17 P-loop domain AAA_7 PF12775.7 OQS04344.1 - 0.00054 19.5 0.0 0.0013 18.2 0.0 1.6 1 0 0 1 1 1 1 P-loop containing dynein motor region NACHT PF05729.12 OQS04344.1 - 0.00067 19.6 0.0 0.0015 18.5 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA_33 PF13671.6 OQS04344.1 - 0.0011 19.2 0.0 0.0076 16.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.14 OQS04344.1 - 0.0012 18.8 0.0 0.0044 17.0 0.0 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 OQS04344.1 - 0.0018 18.8 0.0 0.0059 17.2 0.0 1.9 1 0 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 OQS04344.1 - 0.0019 18.0 0.0 0.0038 17.0 0.0 1.5 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA_22 PF13401.6 OQS04344.1 - 0.0045 17.3 0.0 0.019 15.2 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 OQS04344.1 - 0.0049 16.6 0.0 0.013 15.2 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 OQS04344.1 - 0.023 14.4 0.0 0.067 12.9 0.0 1.8 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 OQS04344.1 - 0.024 13.9 0.0 0.072 12.4 0.0 1.8 1 0 0 1 1 1 0 Zeta toxin TniB PF05621.11 OQS04344.1 - 0.026 13.9 0.1 1.4 8.2 0.0 2.6 2 0 0 2 2 2 0 Bacterial TniB protein RNA_helicase PF00910.22 OQS04344.1 - 0.033 14.6 0.0 0.11 12.9 0.0 2.1 1 1 0 1 1 1 0 RNA helicase TsaE PF02367.17 OQS04344.1 - 0.037 14.0 0.0 0.088 12.8 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE MCM PF00493.23 OQS04344.1 - 0.038 13.1 0.7 0.22 10.6 0.0 2.1 2 0 0 2 2 2 0 MCM P-loop domain CbiA PF01656.23 OQS04344.1 - 0.041 13.9 0.4 0.15 12.2 0.4 2.3 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_19 PF13245.6 OQS04344.1 - 0.043 14.2 0.1 0.16 12.3 0.0 1.9 2 0 0 2 2 1 0 AAA domain ABC_tran PF00005.27 OQS04344.1 - 0.053 14.0 1.7 0.45 11.0 0.0 3.3 3 1 0 4 4 4 0 ABC transporter AAA_28 PF13521.6 OQS04344.1 - 0.055 13.7 0.0 0.18 12.0 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 OQS04344.1 - 0.065 12.8 0.0 0.42 10.2 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.6 OQS04344.1 - 0.089 12.8 0.0 0.21 11.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain ResIII PF04851.15 OQS04344.1 - 0.11 12.6 0.0 0.87 9.6 0.0 2.6 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit zf-CCCH_4 PF18044.1 OQS04347.1 - 6.9e-13 48.1 14.4 3.6e-06 26.7 3.2 3.0 2 0 0 2 2 2 2 CCCH-type zinc finger zf_CCCH_4 PF18345.1 OQS04347.1 - 1.4e-10 40.9 25.9 6.4e-06 26.0 7.2 3.0 3 0 0 3 3 3 2 Zinc finger domain zf-CCCH PF00642.24 OQS04347.1 - 4e-10 39.3 14.8 2e-05 24.4 3.3 3.1 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CHY PF05495.12 OQS04347.1 - 5.3e-07 30.0 11.5 5.3e-07 30.0 11.5 4.5 3 2 1 4 4 2 1 CHY zinc finger Myb_DNA-binding PF00249.31 OQS04347.1 - 4.8e-05 23.5 0.1 4.8e-05 23.5 0.1 2.0 2 0 0 2 2 1 1 Myb-like DNA-binding domain Torus PF16131.5 OQS04347.1 - 0.00015 22.4 18.2 0.0026 18.4 2.0 3.1 2 1 1 3 3 2 2 Torus domain zf-CCCH_2 PF14608.6 OQS04347.1 - 0.0031 17.9 20.5 0.065 13.7 4.3 3.3 3 0 0 3 3 2 2 RNA-binding, Nab2-type zinc finger RWD PF05773.22 OQS04347.1 - 0.0073 16.6 0.0 0.023 15.0 0.0 1.9 1 0 0 1 1 1 1 RWD domain zf-CCCH_3 PF15663.5 OQS04347.1 - 0.0092 16.2 17.4 0.0096 16.1 0.5 3.7 2 1 0 3 3 3 2 Zinc-finger containing family NLRC4_HD2 PF17776.1 OQS04347.1 - 0.011 16.2 0.3 3.2 8.3 0.0 2.8 2 0 0 2 2 2 0 NLRC4 helical domain HD2 Myb_DNA-bind_6 PF13921.6 OQS04347.1 - 0.025 14.8 0.8 0.093 13.0 0.0 2.2 2 0 0 2 2 2 0 Myb-like DNA-binding domain Ank_2 PF12796.7 OQS04348.1 - 1.9e-27 95.7 21.2 6.5e-12 45.9 2.2 3.1 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQS04348.1 - 1.3e-21 76.6 5.8 3.1e-08 34.0 0.0 4.1 3 1 1 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQS04348.1 - 1.3e-18 65.1 8.1 2.7e-07 30.4 0.1 4.8 4 0 0 4 4 4 3 Ankyrin repeat Ank PF00023.30 OQS04348.1 - 1.7e-17 63.0 13.6 1.2e-06 28.6 0.3 4.6 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.6 OQS04348.1 - 3.5e-16 59.0 10.2 3.5e-06 27.2 0.1 4.4 2 1 2 4 4 4 4 Ankyrin repeats (many copies) UPRTase PF14681.6 OQS04349.1 - 1.1e-27 96.8 0.0 3.6e-27 95.1 0.0 1.7 1 1 0 1 1 1 1 Uracil phosphoribosyltransferase ArsA_ATPase PF02374.15 OQS04349.1 - 0.15 11.3 0.0 0.24 10.5 0.0 1.3 1 0 0 1 1 1 0 Anion-transporting ATPase HA PF03457.14 OQS04350.1 - 4.8e-41 138.9 2.8 1.2e-12 48.0 0.0 5.2 5 0 0 5 5 5 5 Helicase associated domain TFIIE_alpha PF02002.17 OQS04350.1 - 0.025 14.4 1.4 23 4.9 0.0 3.4 3 0 0 3 3 3 0 TFIIE alpha subunit Flu_NS2 PF00601.19 OQS04350.1 - 0.048 14.0 0.3 7.6 6.9 0.0 4.0 3 1 1 4 4 4 0 Influenza non-structural protein (NS2) Apolipoprotein PF01442.18 OQS04351.1 - 0.00019 21.3 37.4 0.0019 18.1 14.1 4.0 2 2 1 3 3 3 2 Apolipoprotein A1/A4/E domain IFT57 PF10498.9 OQS04351.1 - 0.0015 17.6 7.1 0.0015 17.6 7.1 4.7 1 1 3 4 4 4 1 Intra-flagellar transport protein 57 Fez1 PF06818.15 OQS04351.1 - 0.002 18.6 17.8 0.002 18.6 17.8 4.2 1 1 2 3 3 3 1 Fez1 EzrA PF06160.12 OQS04351.1 - 0.0024 16.1 4.5 0.0024 16.1 4.5 2.8 2 1 1 3 3 3 1 Septation ring formation regulator, EzrA PKcGMP_CC PF16808.5 OQS04351.1 - 0.021 14.7 9.2 0.52 10.2 0.1 4.8 4 1 1 5 5 5 0 Coiled-coil N-terminus of cGMP-dependent protein kinase DUF3584 PF12128.8 OQS04351.1 - 0.5 7.8 59.9 1.3 6.5 18.3 3.1 1 1 2 3 3 3 0 Protein of unknown function (DUF3584) DUF1664 PF07889.12 OQS04351.1 - 3.7 7.6 49.3 0.38 10.8 2.7 7.2 1 1 6 8 8 8 0 Protein of unknown function (DUF1664) Pkinase PF00069.25 OQS04352.1 - 5.9e-54 183.2 0.9 6.1e-54 183.1 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQS04352.1 - 1.4e-37 129.4 0.0 3e-37 128.3 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OQS04352.1 - 6.7e-07 28.4 0.3 9.1e-06 24.7 0.0 2.1 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 OQS04352.1 - 1.4e-05 24.5 0.0 2.4e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 Kinase-like zf-piccolo PF05715.13 OQS04352.1 - 0.0054 16.9 0.5 0.011 15.9 0.5 1.4 1 0 0 1 1 1 1 Piccolo Zn-finger APH PF01636.23 OQS04352.1 - 0.0072 16.3 3.9 0.33 10.8 0.1 2.9 2 1 1 3 3 3 1 Phosphotransferase enzyme family DUF3552 PF12072.8 OQS04352.1 - 0.024 14.1 6.3 0.042 13.3 6.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) zf-B_box PF00643.24 OQS04352.1 - 0.044 13.9 0.5 0.089 13.0 0.5 1.4 1 0 0 1 1 1 0 B-box zinc finger ARS2 PF04959.13 OQS04352.1 - 0.36 11.2 2.4 0.68 10.3 2.4 1.4 1 0 0 1 1 1 0 Arsenite-resistance protein 2 FYVE PF01363.21 OQS04353.1 - 2.6e-11 43.5 13.5 6.2e-11 42.3 13.5 1.6 1 0 0 1 1 1 1 FYVE zinc finger START PF01852.19 OQS04353.1 - 1.8e-06 27.6 0.0 5.1e-06 26.0 0.0 1.7 1 1 0 1 1 1 1 START domain FYVE_2 PF02318.16 OQS04353.1 - 0.11 12.7 12.6 0.48 10.6 12.9 1.8 1 1 0 1 1 1 0 FYVE-type zinc finger zf-C3HC4_3 PF13920.6 OQS04354.1 - 5.2e-16 58.2 9.2 7.5e-16 57.7 9.2 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 OQS04354.1 - 5.3e-09 35.8 11.5 8.9e-09 35.1 11.5 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 OQS04354.1 - 1.7e-06 28.3 12.6 2.6e-06 27.6 12.6 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 OQS04354.1 - 0.0027 17.6 11.0 0.0044 17.0 11.0 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C4H2 PF10146.9 OQS04354.1 - 0.0074 16.6 0.3 0.015 15.6 0.3 1.5 1 1 0 1 1 1 1 Zinc finger-containing protein zf-C3HC4_2 PF13923.6 OQS04354.1 - 0.36 10.7 13.2 0.59 10.0 13.2 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 OQS04354.1 - 1.4 8.7 9.6 2.5 8.0 9.6 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Aa_trans PF01490.18 OQS04355.1 - 1.4e-47 162.4 35.6 1.7e-47 162.1 35.6 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein MscS_TM PF12794.7 OQS04355.1 - 0.43 9.4 17.1 0.46 9.3 6.3 2.6 1 1 1 2 2 2 0 Mechanosensitive ion channel inner membrane domain 1 WW PF00397.26 OQS04356.1 - 4.6e-20 71.4 22.1 3.7e-10 39.7 0.5 3.9 3 0 0 3 3 3 3 WW domain TIG PF01833.24 OQS04356.1 - 1.3e-05 25.2 12.5 0.0076 16.3 0.2 4.5 4 1 0 4 4 4 2 IPT/TIG domain zf-RING_2 PF13639.6 OQS04357.1 - 1.3e-09 38.2 7.3 2.5e-09 37.3 7.3 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 OQS04357.1 - 2.6e-08 33.6 6.3 4.5e-08 32.8 6.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 OQS04357.1 - 2.4e-07 30.9 9.0 1.6e-06 28.3 9.0 2.3 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 OQS04357.1 - 3.2e-06 26.9 6.9 8.1e-06 25.6 6.9 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 OQS04357.1 - 3.3e-06 26.8 8.7 9e-06 25.4 8.6 1.8 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 OQS04357.1 - 4.6e-05 23.4 4.1 4.6e-05 23.4 4.1 1.8 2 0 0 2 2 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.6 OQS04357.1 - 0.00015 21.6 9.2 0.0012 18.6 9.2 2.3 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 OQS04357.1 - 0.00042 20.2 9.4 0.0013 18.7 8.3 2.2 1 1 1 2 2 2 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 OQS04357.1 - 0.004 17.1 9.1 0.011 15.7 9.1 1.8 1 0 0 1 1 1 1 RING-type zinc-finger Antistasin PF02822.14 OQS04357.1 - 0.015 16.0 0.8 0.015 16.0 0.8 2.0 2 0 0 2 2 2 0 Antistasin family Rad50_zn_hook PF04423.14 OQS04357.1 - 0.016 15.0 0.6 0.44 10.4 0.0 2.6 2 0 0 2 2 2 0 Rad50 zinc hook motif TerY_C PF15616.6 OQS04357.1 - 0.017 15.3 1.3 0.049 13.7 1.3 1.7 1 0 0 1 1 1 0 TerY-C metal binding domain zf-RING_11 PF17123.5 OQS04357.1 - 0.02 14.6 4.3 0.02 14.6 4.3 2.1 2 0 0 2 2 2 0 RING-like zinc finger Zn_ribbon_17 PF17120.5 OQS04357.1 - 0.12 12.0 3.1 0.22 11.2 3.1 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type Zn-ribbon_8 PF09723.10 OQS04357.1 - 0.17 12.0 5.3 4.7 7.4 1.7 2.7 2 0 0 2 2 2 0 Zinc ribbon domain zf-RING_4 PF14570.6 OQS04357.1 - 0.33 10.8 5.3 0.98 9.3 5.4 1.8 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain zf-RING-like PF08746.11 OQS04357.1 - 0.46 10.8 10.3 0.055 13.8 4.0 2.4 2 0 0 2 2 2 0 RING-like domain DZR PF12773.7 OQS04357.1 - 0.73 9.9 3.5 2.8 8.0 3.4 2.0 1 1 0 1 1 1 0 Double zinc ribbon DNA_ligase_ZBD PF03119.16 OQS04357.1 - 1.3 9.1 7.7 3.8 7.6 1.2 2.5 2 0 0 2 2 2 0 NAD-dependent DNA ligase C4 zinc finger domain PHD PF00628.29 OQS04357.1 - 2.5 8.0 5.1 5.9 6.9 5.1 1.7 1 0 0 1 1 1 0 PHD-finger TMEM154 PF15102.6 OQS04358.1 - 0.00046 20.1 0.2 0.00046 20.1 0.2 2.3 1 1 1 2 2 2 1 TMEM154 protein family TMIE PF16038.5 OQS04358.1 - 0.054 13.3 0.0 0.09 12.6 0.0 1.3 1 0 0 1 1 1 0 TMIE protein Neurensin PF14927.6 OQS04358.1 - 0.089 12.5 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 Neurensin PRCC PF10253.9 OQS04358.1 - 0.69 10.7 8.5 1.6 9.5 8.5 1.7 1 1 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting Hamartin PF04388.12 OQS04358.1 - 2 7.0 8.2 2.1 6.9 8.2 1.2 1 0 0 1 1 1 0 Hamartin protein Pro_isomerase PF00160.21 OQS04359.1 - 7.6e-49 166.0 0.0 1.1e-48 165.5 0.0 1.2 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD ANAPC_CDC26 PF10471.9 OQS04360.1 - 0.00042 21.1 6.1 0.00044 21.0 5.8 1.4 1 1 0 1 1 1 1 Anaphase-promoting complex APC subunit CDC26 MRP-S33 PF08293.11 OQS04360.1 - 0.019 15.2 3.0 0.019 15.2 3.0 1.5 2 0 0 2 2 2 0 Mitochondrial ribosomal subunit S27 Pkinase PF00069.25 OQS04362.1 - 2.1e-49 168.3 0.0 1.1e-48 165.9 0.0 1.9 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQS04362.1 - 5e-47 160.4 0.0 1.3e-46 159.0 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase Ank_2 PF12796.7 OQS04362.1 - 8.2e-41 138.5 9.2 8.6e-14 51.9 0.3 4.5 2 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.30 OQS04362.1 - 6.9e-35 118.0 17.0 9e-08 32.2 0.1 7.2 6 1 1 7 7 7 6 Ankyrin repeat Ank_4 PF13637.6 OQS04362.1 - 7.8e-35 118.8 11.3 2.3e-10 40.8 0.1 6.5 3 1 3 6 6 6 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQS04362.1 - 6.6e-33 109.0 4.5 1.7e-05 24.8 0.1 7.5 7 0 0 7 7 7 6 Ankyrin repeat Ank_5 PF13857.6 OQS04362.1 - 2.2e-28 97.9 11.7 3.8e-10 39.8 0.1 7.0 3 2 5 8 8 8 6 Ankyrin repeats (many copies) Haspin_kinase PF12330.8 OQS04362.1 - 5.5e-05 22.3 1.1 0.00026 20.1 1.1 1.9 1 1 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 OQS04362.1 - 0.0049 15.7 0.0 0.0078 15.0 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Pyridoxal_deC PF00282.19 OQS04363.1 - 1.7e-43 148.8 0.0 2.9e-43 148.0 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Peptidase_M1 PF01433.20 OQS04363.1 - 3e-12 46.6 0.7 3e-12 46.6 0.7 1.8 2 1 0 2 2 2 1 Peptidase family M1 domain Aminotran_5 PF00266.19 OQS04363.1 - 0.00024 20.2 0.0 0.00062 18.8 0.0 1.6 2 0 0 2 2 2 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 OQS04363.1 - 0.0058 15.9 0.0 0.011 15.0 0.0 1.4 1 0 0 1 1 1 1 Beta-eliminating lyase Peptidase_M1_N PF17900.1 OQS04363.1 - 0.026 14.7 0.0 0.047 13.9 0.0 1.4 1 0 0 1 1 1 0 Peptidase M1 N-terminal domain Peptidase_S28 PF05577.12 OQS04364.1 - 1.8e-77 261.0 0.0 2.4e-77 260.6 0.0 1.2 1 0 0 1 1 1 1 Serine carboxypeptidase S28 Peptidase_S37 PF05576.11 OQS04364.1 - 5e-06 25.5 0.0 7.9e-06 24.8 0.0 1.2 1 0 0 1 1 1 1 PS-10 peptidase S37 Peptidase_S9 PF00326.21 OQS04364.1 - 0.0025 17.3 0.0 0.0046 16.5 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 OQS04364.1 - 0.0038 16.9 0.1 0.01 15.5 0.0 1.7 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 OQS04364.1 - 0.02 15.5 0.4 0.053 14.1 0.4 1.7 1 0 0 1 1 1 0 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 OQS04364.1 - 0.03 13.6 0.1 0.059 12.6 0.1 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 DUF4391 PF14335.6 OQS04364.1 - 0.13 12.0 0.1 0.2 11.3 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4391) DUF2920 PF11144.8 OQS04364.1 - 0.14 11.3 0.3 0.24 10.5 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2920) Sec23_trunk PF04811.15 OQS04365.1 - 5.3e-74 248.8 0.0 7.6e-74 248.3 0.0 1.2 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.15 OQS04365.1 - 9.8e-28 96.0 0.0 1.9e-27 95.1 0.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.12 OQS04365.1 - 6e-18 65.4 0.0 1.1e-17 64.6 0.0 1.4 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.15 OQS04365.1 - 4.6e-17 61.8 3.2 8.9e-17 60.9 3.2 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 OQS04365.1 - 5.7e-10 39.0 0.0 1.6e-09 37.5 0.0 1.7 1 0 0 1 1 1 1 Gelsolin repeat MRNIP PF15749.5 OQS04365.1 - 0.03 15.0 0.3 0.052 14.3 0.3 1.3 1 0 0 1 1 1 0 MRN-interacting protein UPF0047 PF01894.17 OQS04366.1 - 2.4e-36 124.4 0.0 2.7e-36 124.2 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family UPF0047 ECH_2 PF16113.5 OQS04367.1 - 1.9e-116 389.2 0.0 2.8e-116 388.7 0.0 1.3 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_1 PF00378.20 OQS04367.1 - 3e-33 115.2 0.0 2.8e-31 108.7 0.0 2.2 2 0 0 2 2 2 2 Enoyl-CoA hydratase/isomerase zf-H2C2_2 PF13465.6 OQS04368.1 - 2.6e-13 49.7 37.5 1.2e-05 25.5 0.4 7.1 8 0 0 8 8 8 4 Zinc-finger double domain zf-C2H2 PF00096.26 OQS04368.1 - 1.3e-08 34.8 37.2 1.4e-05 25.2 1.1 6.1 6 2 0 6 6 6 4 Zinc finger, C2H2 type zf-met PF12874.7 OQS04368.1 - 3.8e-05 23.9 1.3 0.49 10.9 0.5 3.2 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 OQS04368.1 - 0.00049 20.0 13.9 0.48 10.5 0.2 4.9 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 OQS04368.1 - 0.0005 20.3 4.5 1.5 9.2 0.3 4.2 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-C2H2_11 PF16622.5 OQS04368.1 - 0.00067 19.4 0.8 0.00067 19.4 0.8 3.7 5 0 0 5 5 5 1 zinc-finger C2H2-type zf-C2H2_4 PF13894.6 OQS04368.1 - 0.0059 17.3 39.1 0.032 15.1 1.4 6.5 6 1 0 6 6 6 4 C2H2-type zinc finger PH PF00169.29 OQS04369.1 - 7.8e-26 90.6 0.5 2.1e-12 47.5 0.0 2.7 2 1 0 2 2 2 2 PH domain PH_8 PF15409.6 OQS04369.1 - 4.1e-12 46.2 0.7 7.2e-06 26.2 0.1 2.3 2 0 0 2 2 2 2 Pleckstrin homology domain PH_11 PF15413.6 OQS04369.1 - 4.4e-11 43.1 8.9 0.00015 22.2 0.8 4.0 2 2 0 2 2 2 2 Pleckstrin homology domain PH_3 PF14593.6 OQS04369.1 - 3.5e-06 27.0 0.0 0.0094 16.0 0.0 2.2 2 0 0 2 2 2 2 PH domain PH_9 PF15410.6 OQS04369.1 - 0.034 14.5 0.7 1.5 9.2 0.1 3.3 2 2 1 3 3 3 0 Pleckstrin homology domain Mcp5_PH PF12814.7 OQS04369.1 - 0.034 14.3 0.1 0.46 10.6 0.1 2.6 1 1 1 2 2 2 0 Meiotic cell cortex C-terminal pleckstrin homology Dpoe2NT PF12213.8 OQS04369.1 - 0.039 14.2 0.0 6.4 7.1 0.0 2.3 2 0 0 2 2 2 0 DNA polymerases epsilon N terminal BCL_N PF04714.13 OQS04369.1 - 0.1 12.7 0.5 1.2 9.2 0.1 2.4 2 0 0 2 2 2 0 BCL7, N-terminal conserver region PH PF00169.29 OQS04370.1 - 2e-20 73.2 1.4 1e-09 38.8 0.2 3.0 2 1 0 2 2 2 2 PH domain PH_11 PF15413.6 OQS04370.1 - 3e-07 30.8 6.4 0.01 16.3 0.4 3.3 2 1 1 3 3 3 2 Pleckstrin homology domain PH_8 PF15409.6 OQS04370.1 - 5.4e-07 29.8 0.4 0.00013 22.2 0.1 2.4 2 0 0 2 2 2 2 Pleckstrin homology domain PH_3 PF14593.6 OQS04370.1 - 0.018 15.1 0.0 0.45 10.6 0.0 2.3 2 0 0 2 2 2 0 PH domain Epimerase PF01370.21 OQS04371.1 - 1.4e-07 31.2 0.0 2.1e-07 30.6 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 OQS04371.1 - 7.5e-06 25.6 0.1 1.1e-05 25.0 0.1 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 OQS04371.1 - 0.00018 20.6 0.0 0.00024 20.2 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.25 OQS04371.1 - 0.0021 17.5 0.0 0.0029 17.1 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OQS04371.1 - 0.028 14.3 0.2 0.053 13.4 0.2 1.4 1 0 0 1 1 1 0 KR domain NAD_binding_4 PF07993.12 OQS04371.1 - 0.057 12.6 0.1 0.084 12.0 0.1 1.3 1 0 0 1 1 1 0 Male sterility protein UDPG_MGDP_dh_N PF03721.14 OQS04371.1 - 0.063 12.9 0.1 0.12 11.9 0.1 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain RmlD_sub_bind PF04321.17 OQS04371.1 - 0.1 11.7 0.0 0.16 11.0 0.0 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain EF-hand_1 PF00036.32 OQS04372.1 - 1.5e-12 46.1 11.1 5.5e-05 22.4 0.5 4.4 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.6 OQS04372.1 - 6.9e-10 38.1 7.5 0.014 15.3 0.1 4.5 4 0 0 4 4 4 3 EF-hand domain EF-hand_7 PF13499.6 OQS04372.1 - 8e-10 39.0 11.3 4.2e-06 27.1 5.0 3.4 3 1 0 4 4 4 2 EF-hand domain pair EF-hand_5 PF13202.6 OQS04372.1 - 3.5e-09 35.7 6.4 0.0017 17.8 0.5 3.6 3 0 0 3 3 3 3 EF hand EF-hand_8 PF13833.6 OQS04372.1 - 0.0002 21.1 9.6 0.83 9.5 0.0 3.8 3 0 0 3 3 3 3 EF-hand domain pair Retrotran_gag_2 PF14223.6 OQS04373.1 - 0.32 10.6 3.7 18 5.0 0.1 3.8 4 0 0 4 4 4 0 gag-polypeptide of LTR copia-type DUF4229 PF14012.6 OQS04374.1 - 8.1 6.6 8.7 11 6.2 1.3 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF4229) UQ_con PF00179.26 OQS04376.1 - 4.2e-41 139.9 0.0 4.8e-41 139.7 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme NADH_B2 PF14813.6 OQS04379.1 - 0.072 12.9 1.2 0.1 12.4 1.2 1.3 1 0 0 1 1 1 0 NADH dehydrogenase 1 beta subcomplex subunit 2 Synaptobrevin PF00957.21 OQS04380.1 - 1.9e-32 110.9 1.0 3.4e-32 110.1 1.0 1.4 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.6 OQS04380.1 - 1.7e-24 85.7 0.2 2.7e-24 85.0 0.2 1.3 1 0 0 1 1 1 1 Regulated-SNARE-like domain Orbi_VP3 PF01700.16 OQS04380.1 - 0.00081 17.4 0.1 0.00095 17.2 0.1 1.2 1 0 0 1 1 1 1 Orbivirus VP3 (T2) protein GP40 PF11025.8 OQS04381.1 - 0.12 12.1 1.1 0.23 11.2 1.1 1.4 1 0 0 1 1 1 0 Glycoprotein GP40 of Cryptosporidium DUF1765 PF08578.10 OQS04382.1 - 6.9e-10 39.5 2.5 3.4e-09 37.2 2.5 2.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1765) Methyltransf_15 PF09445.10 OQS04383.1 - 1.9e-37 128.4 0.0 2.7e-37 127.9 0.0 1.2 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase UPF0020 PF01170.18 OQS04383.1 - 7.9e-07 28.9 0.0 4.3e-06 26.6 0.0 2.0 2 0 0 2 2 2 1 Putative RNA methylase family UPF0020 Methyltransf_31 PF13847.6 OQS04383.1 - 1.8e-06 27.9 0.1 4e-06 26.7 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Met_10 PF02475.16 OQS04383.1 - 1.8e-06 27.9 0.0 3e-06 27.1 0.0 1.4 1 0 0 1 1 1 1 Met-10+ like-protein Cons_hypoth95 PF03602.15 OQS04383.1 - 2.8e-06 27.1 0.0 5.2e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_25 PF13649.6 OQS04383.1 - 3.8e-06 27.5 0.0 1.1e-05 26.1 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 OQS04383.1 - 0.00011 21.7 1.3 0.00012 21.6 0.1 1.6 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_11 PF08241.12 OQS04383.1 - 0.00013 22.6 0.1 0.00037 21.1 0.0 1.7 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_3 PF01596.17 OQS04383.1 - 0.00045 19.4 0.0 0.0008 18.6 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_18 PF12847.7 OQS04383.1 - 0.0023 17.9 0.0 0.0062 16.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain CobT_C PF11775.8 OQS04383.1 - 0.022 14.4 0.0 0.045 13.4 0.0 1.5 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT VWA domain TRM PF02005.16 OQS04383.1 - 0.035 13.3 0.0 0.046 12.9 0.0 1.3 1 0 0 1 1 1 0 N2,N2-dimethylguanosine tRNA methyltransferase MTS PF05175.14 OQS04383.1 - 0.039 13.5 0.0 0.075 12.6 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain DTHCT PF08070.11 OQS04383.1 - 5.6 7.8 10.1 12 6.7 1.6 2.2 2 0 0 2 2 2 0 DTHCT (NUC029) region IFT20 PF14931.6 OQS04384.1 - 1.1e-36 125.5 14.1 1.9e-36 124.8 14.1 1.4 1 0 0 1 1 1 1 Intraflagellar transport complex B, subunit 20 PDZ_6 PF17820.1 OQS04384.1 - 3.9e-08 33.0 0.1 9.6e-08 31.8 0.1 1.7 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 OQS04384.1 - 8.4e-05 22.9 0.0 0.00017 21.9 0.0 1.7 1 0 0 1 1 1 1 PDZ domain CSN7a_helixI PF18392.1 OQS04384.1 - 0.045 13.7 0.5 0.14 12.1 0.5 1.9 1 0 0 1 1 1 0 COP9 signalosome complex subunit 7a helix I domain B56 PF01603.20 OQS04385.1 - 8.1e-17 61.3 0.3 3e-15 56.1 0.3 2.3 1 1 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) PAM2 PF07145.15 OQS04385.1 - 0.016 14.9 1.3 0.045 13.4 1.3 1.9 1 1 0 1 1 1 0 Ataxin-2 C-terminal region Phosducin PF02114.16 OQS04385.1 - 0.08 11.9 0.0 0.13 11.1 0.0 1.3 1 0 0 1 1 1 0 Phosducin Arm_2 PF04826.13 OQS04386.1 - 0.0012 18.3 0.1 0.29 10.6 0.0 2.4 1 1 1 2 2 2 2 Armadillo-like Arm PF00514.23 OQS04386.1 - 0.055 13.5 1.3 7.9 6.7 0.6 3.2 2 1 0 2 2 2 0 Armadillo/beta-catenin-like repeat SpoU_methylase PF00588.19 OQS04387.1 - 1.9e-25 89.7 0.0 3.9e-25 88.7 0.0 1.6 1 0 0 1 1 1 1 SpoU rRNA Methylase family FYVE PF01363.21 OQS04387.1 - 2.2e-13 50.1 9.2 7.9e-13 48.3 9.2 2.0 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.16 OQS04387.1 - 0.029 14.6 4.7 0.094 12.9 4.7 1.9 1 0 0 1 1 1 0 FYVE-type zinc finger Med12 PF09497.10 OQS04387.1 - 0.11 12.9 0.0 0.33 11.3 0.0 1.8 1 0 0 1 1 1 0 Transcription mediator complex subunit Med12 Zf_RING PF16744.5 OQS04387.1 - 2.2 8.4 6.7 7.1 6.8 6.7 1.8 1 0 0 1 1 1 0 KIAA1045 RING finger RHSP PF07999.11 OQS04389.1 - 0.0032 16.4 0.1 0.0036 16.2 0.1 1.1 1 0 0 1 1 1 1 Retrotransposon hot spot protein Microtub_bd PF16796.5 OQS04389.1 - 0.0039 17.1 0.1 0.0047 16.9 0.1 1.2 1 0 0 1 1 1 1 Microtubule binding ABC_tran PF00005.27 OQS04389.1 - 0.0079 16.7 0.5 0.022 15.3 0.4 1.8 1 1 1 2 2 2 1 ABC transporter AAA_16 PF13191.6 OQS04389.1 - 0.02 15.3 0.0 0.027 14.8 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain DUF87 PF01935.17 OQS04389.1 - 0.026 14.6 0.0 0.034 14.2 0.0 1.3 1 0 0 1 1 1 0 Helicase HerA, central domain SMC_N PF02463.19 OQS04389.1 - 0.049 13.1 0.0 0.068 12.6 0.0 1.2 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain AAA_10 PF12846.7 OQS04389.1 - 0.055 12.4 0.1 0.069 12.1 0.1 1.1 1 0 0 1 1 1 0 AAA-like domain AAA_29 PF13555.6 OQS04389.1 - 0.12 12.1 0.2 0.41 10.4 0.1 1.9 1 1 1 2 2 2 0 P-loop containing region of AAA domain PPR_2 PF13041.6 OQS04390.1 - 9.8e-16 57.7 3.0 0.47 10.7 0.1 8.4 8 0 0 8 8 8 5 PPR repeat family PPR_long PF17177.4 OQS04390.1 - 1.4e-09 37.6 20.1 8.6e-05 22.0 1.7 6.8 4 2 4 8 8 8 3 Pentacotripeptide-repeat region of PRORP PPR_3 PF13812.6 OQS04390.1 - 2.5e-06 27.5 7.9 0.52 10.4 0.0 6.9 7 1 1 8 8 8 2 Pentatricopeptide repeat domain PPR PF01535.20 OQS04390.1 - 8.5e-05 22.6 3.0 2.5 8.6 0.1 6.6 7 0 0 7 7 7 1 PPR repeat DUF1548 PF07579.11 OQS04390.1 - 0.0057 17.0 5.5 0.34 11.2 0.0 3.3 3 1 0 3 3 3 2 Domain of Unknown Function (DUF1548) PPR_1 PF12854.7 OQS04390.1 - 0.028 14.1 0.1 47 3.8 0.0 4.0 3 0 0 3 3 3 0 PPR repeat RHSP PF07999.11 OQS04391.1 - 0.0011 17.9 0.0 0.0014 17.5 0.0 1.1 1 0 0 1 1 1 1 Retrotransposon hot spot protein DAP3 PF10236.9 OQS04391.1 - 0.047 12.9 0.0 0.063 12.4 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 MCM PF00493.23 OQS04391.1 - 0.064 12.4 0.0 0.087 11.9 0.0 1.1 1 0 0 1 1 1 0 MCM P-loop domain ABC_tran PF00005.27 OQS04391.1 - 0.075 13.5 0.0 0.12 12.9 0.0 1.4 1 0 0 1 1 1 0 ABC transporter SMC_N PF02463.19 OQS04391.1 - 0.091 12.2 0.0 0.14 11.6 0.0 1.2 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain FtsK_SpoIIIE PF01580.18 OQS04391.1 - 0.2 10.9 0.0 0.31 10.4 0.0 1.2 1 0 0 1 1 1 0 FtsK/SpoIIIE family DUF87 PF01935.17 OQS04391.1 - 0.22 11.6 0.0 0.35 10.9 0.0 1.3 1 0 0 1 1 1 0 Helicase HerA, central domain DUF4215 PF13948.6 OQS04393.1 - 7.7e-82 269.5 218.8 6.6e-08 32.9 4.5 15.9 11 4 4 15 15 15 13 Domain of unknown function (DUF4215) Tyrosinase PF00264.20 OQS04393.1 - 3.7e-24 86.3 0.0 1.1e-23 84.8 0.0 1.8 1 0 0 1 1 1 1 Common central domain of tyrosinase Thioredoxin PF00085.20 OQS04395.1 - 1.2e-27 95.9 1.5 1.5e-27 95.6 0.2 1.8 2 0 0 2 2 2 1 Thioredoxin AMP-binding PF00501.28 OQS04395.1 - 8.2e-11 41.1 0.0 1.2e-10 40.6 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme OST3_OST6 PF04756.13 OQS04395.1 - 0.0026 17.2 0.0 0.004 16.5 0.0 1.2 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_2 PF13098.6 OQS04395.1 - 0.005 17.3 0.4 0.013 16.0 0.4 1.7 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 OQS04395.1 - 0.01 16.1 0.1 0.025 14.9 0.1 1.7 1 0 0 1 1 1 0 Thioredoxin-like Thioredoxin_7 PF13899.6 OQS04395.1 - 0.019 15.1 0.1 0.05 13.8 0.1 1.8 1 0 0 1 1 1 0 Thioredoxin-like Ank_2 PF12796.7 OQS04396.1 - 2.2e-39 133.9 1.0 2.5e-14 53.6 0.0 5.3 2 1 2 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQS04396.1 - 4.4e-36 122.8 3.3 3.8e-08 33.7 0.0 8.2 4 2 4 8 8 8 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQS04396.1 - 5.2e-31 103.2 9.8 4.3e-07 29.7 0.0 9.0 9 1 1 10 10 10 7 Ankyrin repeat Ank PF00023.30 OQS04396.1 - 3.2e-29 100.1 10.4 8.8e-05 22.8 0.0 8.8 9 0 0 9 9 9 6 Ankyrin repeat TIR_2 PF13676.6 OQS04396.1 - 1.2e-26 93.6 0.0 1.9e-16 60.7 0.0 2.6 2 0 0 2 2 2 2 TIR domain Ank_5 PF13857.6 OQS04396.1 - 2.6e-25 88.1 2.1 3.3e-09 36.8 0.0 7.0 4 2 2 6 6 6 5 Ankyrin repeats (many copies) TIR PF01582.20 OQS04396.1 - 9.7e-10 38.5 0.1 5.1e-06 26.4 0.0 3.1 3 0 0 3 3 3 2 TIR domain DUF1863 PF08937.11 OQS04396.1 - 0.072 13.4 0.1 0.71 10.2 0.0 2.6 2 1 0 2 2 2 0 MTH538 TIR-like domain (DUF1863) FMN_dh PF01070.18 OQS04397.1 - 0.19 10.7 0.0 0.27 10.2 0.0 1.2 1 0 0 1 1 1 0 FMN-dependent dehydrogenase GRDP-like PF07173.12 OQS04398.1 - 7.3e-14 52.6 0.1 2.2e-13 51.1 0.1 1.8 1 0 0 1 1 1 1 Glycine-rich domain-containing protein-like YqzE PF14038.6 OQS04398.1 - 0.13 12.3 0.2 0.26 11.3 0.2 1.4 1 0 0 1 1 1 0 YqzE-like protein DUF2039 PF10217.9 OQS04398.1 - 0.85 10.0 6.7 0.38 11.1 3.5 2.0 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2039) Zn_Tnp_IS1595 PF12760.7 OQS04398.1 - 1.2 9.2 4.7 5.3 7.1 0.1 2.7 2 0 0 2 2 2 0 Transposase zinc-ribbon domain RRM_1 PF00076.22 OQS04399.1 - 0.15 11.9 0.1 3.4 7.6 0.0 2.8 3 0 0 3 3 3 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CDC27 PF09507.10 OQS04399.1 - 2.3 7.5 21.3 0.039 13.4 13.2 2.0 3 0 0 3 3 3 0 DNA polymerase subunit Cdc27 Homeobox_KN PF05920.11 OQS04400.1 - 1.4e-11 44.1 0.1 2.7e-11 43.2 0.1 1.5 1 0 0 1 1 1 1 Homeobox KN domain Homeodomain PF00046.29 OQS04400.1 - 1.1e-07 31.6 0.1 2.6e-07 30.4 0.1 1.6 1 0 0 1 1 1 1 Homeodomain Glyco_hydro_38C PF07748.13 OQS04400.1 - 0.14 12.2 0.0 0.23 11.5 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolases family 38 C-terminal domain Pkinase_Tyr PF07714.17 OQS04401.1 - 2.3e-10 40.2 0.2 8.2e-10 38.4 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.25 OQS04401.1 - 1.1e-06 28.3 0.0 1.1e-06 28.3 0.0 2.8 3 1 0 3 3 3 1 Protein kinase domain Arm PF00514.23 OQS04401.1 - 1.4e-06 28.1 1.7 0.0071 16.3 0.1 4.1 4 0 0 4 4 4 2 Armadillo/beta-catenin-like repeat Atx10homo_assoc PF09759.9 OQS04401.1 - 0.035 14.1 6.3 0.086 12.9 0.0 4.6 3 2 3 6 6 6 0 Spinocerebellar ataxia type 10 protein domain DUF4472 PF14739.6 OQS04401.1 - 0.079 13.7 37.6 0.33 11.7 11.1 4.1 1 1 1 3 3 3 0 Domain of unknown function (DUF4472) WXG100 PF06013.12 OQS04401.1 - 0.24 11.7 9.0 5 7.4 0.4 3.1 2 0 0 2 2 2 0 Proteins of 100 residues with WXG TSC22 PF01166.18 OQS04401.1 - 0.25 11.7 8.9 0.094 13.0 0.7 4.1 3 0 0 3 3 3 0 TSC-22/dip/bun family KASH_CCD PF14662.6 OQS04401.1 - 1.6 8.5 55.3 3.3 7.5 30.1 3.9 2 1 2 4 4 4 0 Coiled-coil region of CCDC155 or KASH LPP PF04728.13 OQS04401.1 - 1.7 9.1 13.2 14 6.2 4.5 4.3 2 1 1 3 3 3 0 Lipoprotein leucine-zipper GAS PF13851.6 OQS04401.1 - 3.7 6.9 54.2 6.9 6.0 9.0 3.8 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding Fez1 PF06818.15 OQS04401.1 - 9.1 6.7 45.1 16 5.9 15.6 2.7 1 1 1 2 2 2 0 Fez1 zf-A20 PF01754.16 OQS04402.1 - 9.6e-12 44.6 6.2 9.6e-12 44.6 6.2 2.0 2 0 0 2 2 2 1 A20-like zinc finger zf-AN1 PF01428.16 OQS04402.1 - 2e-10 40.6 7.7 2e-10 40.6 7.7 1.7 2 0 0 2 2 2 1 AN1-like Zinc finger EMP24_GP25L PF01105.24 OQS04404.1 - 2.1e-33 115.8 0.1 2.4e-33 115.6 0.1 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD AKNA PF12443.8 OQS04404.1 - 0.014 16.0 1.2 0.49 11.1 0.2 2.2 2 0 0 2 2 2 0 AT-hook-containing transcription factor Rib PF08428.10 OQS04404.1 - 0.028 14.4 0.1 0.45 10.5 0.1 2.2 2 0 0 2 2 2 0 Rib/alpha-like repeat 60KD_IMP PF02096.20 OQS04404.1 - 0.069 13.1 0.1 0.093 12.6 0.1 1.2 1 0 0 1 1 1 0 60Kd inner membrane protein zf-RING_2 PF13639.6 OQS04405.1 - 1.7e-14 53.8 6.4 1.7e-14 53.8 6.4 2.5 2 0 0 2 2 2 1 Ring finger domain PA PF02225.22 OQS04405.1 - 3.4e-13 49.4 0.0 5.6e-13 48.7 0.0 1.4 1 0 0 1 1 1 1 PA domain zf-rbx1 PF12678.7 OQS04405.1 - 1.6e-09 37.9 4.1 1.6e-09 37.9 4.1 2.1 2 0 0 2 2 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 OQS04405.1 - 2.4e-08 33.7 6.3 2.4e-08 33.7 6.3 2.8 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 OQS04405.1 - 2.4e-07 30.3 4.8 2.4e-07 30.3 4.8 2.4 2 1 0 2 2 2 1 Zinc-ribbon, C4HC2 type zf-RING_11 PF17123.5 OQS04405.1 - 3.4e-07 29.9 4.3 3.4e-07 29.9 4.3 3.7 4 0 0 4 4 4 1 RING-like zinc finger zf-C3HC4_3 PF13920.6 OQS04405.1 - 3.5e-07 30.0 11.8 8.4e-07 28.8 4.7 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OQS04405.1 - 1.8e-06 27.8 4.1 1.8e-06 27.8 4.1 2.4 2 0 0 2 2 2 1 zinc-RING finger domain Prok-RING_4 PF14447.6 OQS04405.1 - 1.4e-05 24.8 4.0 1.4e-05 24.8 4.0 2.5 2 1 0 2 2 2 1 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 OQS04405.1 - 7.5e-05 22.7 2.1 0.00016 21.6 2.1 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4 PF00097.25 OQS04405.1 - 0.00013 21.8 5.7 0.00013 21.8 5.7 3.0 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OQS04405.1 - 0.00018 21.5 1.1 0.00018 21.5 1.1 3.5 3 1 1 4 4 4 1 RING-type zinc-finger FANCL_C PF11793.8 OQS04405.1 - 0.0069 16.5 5.9 0.05 13.8 4.1 2.9 2 1 1 3 3 3 1 FANCL C-terminal domain ZNRF_3_ecto PF18212.1 OQS04405.1 - 0.014 15.4 0.0 0.03 14.3 0.0 1.6 1 0 0 1 1 1 0 ZNRF-3 Ectodomain RINGv PF12906.7 OQS04405.1 - 0.022 14.9 3.6 0.022 14.9 3.6 2.3 2 1 0 2 2 2 0 RING-variant domain zf-BED PF02892.15 OQS04405.1 - 0.075 13.1 1.4 0.54 10.3 0.0 2.9 3 0 0 3 3 3 0 BED zinc finger DZR PF12773.7 OQS04405.1 - 0.075 13.1 1.2 0.075 13.1 1.2 2.6 2 1 0 2 2 2 0 Double zinc ribbon HalOD2 PF18547.1 OQS04405.1 - 0.096 12.6 0.7 3.9 7.5 0.1 2.8 2 0 0 2 2 2 0 Halobacterial output domain 2 zf-RING_10 PF16685.5 OQS04405.1 - 0.13 12.5 10.2 0.078 13.1 3.4 2.8 3 0 0 3 3 3 0 zinc RING finger of MSL2 zf-RING_6 PF14835.6 OQS04405.1 - 0.78 9.7 5.8 0.35 10.8 1.3 2.4 2 0 0 2 2 2 0 zf-RING of BARD1-type protein zf-C3H2C3 PF17122.5 OQS04405.1 - 1.2 9.2 7.8 0.25 11.4 3.6 2.1 2 0 0 2 2 2 0 Zinc-finger Prok-RING_1 PF14446.6 OQS04405.1 - 2.5 8.1 12.1 7.4 6.6 1.8 3.7 4 0 0 4 4 4 0 Prokaryotic RING finger family 1 zf-HC5HC2H PF13771.6 OQS04405.1 - 2.5 8.4 7.9 0.19 12.0 1.3 2.5 2 1 0 2 2 2 0 PHD-like zinc-binding domain zinc_ribbon_16 PF17034.5 OQS04405.1 - 8.2 6.7 8.2 39 4.5 1.0 3.3 2 2 1 3 3 3 0 Zinc-ribbon like family Pkinase PF00069.25 OQS04406.1 - 7.6e-52 176.3 0.2 2.1e-25 89.6 0.1 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OQS04406.1 - 1.8e-51 174.9 0.7 7.7e-27 94.2 0.1 2.4 2 0 0 2 2 2 2 Protein tyrosine kinase TMEM154 PF15102.6 OQS04406.1 - 8e-08 32.3 2.7 0.04 13.8 0.2 3.6 3 0 0 3 3 3 2 TMEM154 protein family Stevor PF17410.2 OQS04406.1 - 7.9e-06 25.6 0.3 0.2 11.2 0.0 3.4 3 0 0 3 3 3 2 Subtelomeric Variable Open Reading frame Orf78 PF06024.12 OQS04406.1 - 2.7e-05 24.4 0.0 1.4 9.2 0.2 3.4 3 0 0 3 3 3 1 Orf78 (ac78) CD34_antigen PF06365.12 OQS04406.1 - 0.00014 21.6 0.6 0.26 10.8 0.0 3.3 3 0 0 3 3 3 1 CD34/Podocalyxin family EphA2_TM PF14575.6 OQS04406.1 - 0.00018 22.3 0.2 8.6 7.3 0.0 3.5 3 0 0 3 3 3 0 Ephrin type-A receptor 2 transmembrane domain DUF2207 PF09972.9 OQS04406.1 - 0.00032 19.6 0.0 1.4 7.6 0.0 3.0 3 0 0 3 3 3 2 Predicted membrane protein (DUF2207) DUF202 PF02656.15 OQS04406.1 - 0.00099 19.5 4.5 1.2 9.7 0.0 4.2 4 0 0 4 4 4 1 Domain of unknown function (DUF202) LRR_8 PF13855.6 OQS04406.1 - 0.0012 18.5 0.1 0.44 10.4 0.2 3.8 2 1 2 4 4 4 2 Leucine rich repeat DUF4366 PF14283.6 OQS04406.1 - 0.0036 17.4 0.1 0.77 9.8 0.0 3.0 3 0 0 3 3 3 1 Domain of unknown function (DUF4366) BatD PF13584.6 OQS04406.1 - 0.0051 15.7 0.2 4.1 6.1 0.0 3.0 3 0 0 3 3 3 1 Oxygen tolerance DUF4293 PF14126.6 OQS04406.1 - 0.0077 16.5 2.1 1.1 9.5 0.0 3.5 3 0 0 3 3 3 1 Domain of unknown function (DUF4293) DUF4381 PF14316.6 OQS04406.1 - 0.0088 16.3 4.4 17 5.6 0.3 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4381) LPG_synthase_TM PF03706.13 OQS04406.1 - 0.0095 15.5 2.3 5.1 6.5 0.1 3.1 3 0 0 3 3 3 1 Lysylphosphatidylglycerol synthase TM region Pox_EPC_I2-L1 PF12575.8 OQS04406.1 - 0.015 15.5 5.7 0.31 11.3 0.9 3.4 3 0 0 3 3 3 0 Poxvirus entry protein complex L1 and I2 RIFIN PF02009.16 OQS04406.1 - 0.022 14.7 0.1 4.4 7.1 0.1 2.9 3 0 0 3 3 3 0 Rifin DUF2569 PF10754.9 OQS04406.1 - 0.033 14.6 0.6 7.9 6.9 0.0 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2569) DUF2615 PF11027.8 OQS04406.1 - 0.038 14.1 0.3 3.3 7.9 0.1 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2615) DUF996 PF06195.13 OQS04406.1 - 0.045 14.0 1.0 11 6.3 0.1 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF996) Yip1 PF04893.17 OQS04406.1 - 0.046 13.4 0.2 12 5.6 0.0 3.1 3 0 0 3 3 3 0 Yip1 domain DUF5305 PF17231.2 OQS04406.1 - 0.1 12.0 1.1 6.7 6.0 0.0 3.0 3 0 0 3 3 3 0 Family of unknown function (DUF5305) DUF2976 PF11190.8 OQS04406.1 - 0.3 10.9 1.7 6.4 6.7 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2976) LRR_4 PF12799.7 OQS04406.1 - 0.31 11.5 13.7 0.31 11.5 0.1 5.3 4 2 3 7 7 5 0 Leucine Rich repeats (2 copies) BatA PF07584.11 OQS04406.1 - 1.7 9.0 10.5 0.8 10.1 0.8 3.3 3 0 0 3 3 3 0 Aerotolerance regulator N-terminal Git3 PF11710.8 OQS04406.1 - 2.8 7.7 6.4 4.2 7.1 0.4 3.3 3 0 0 3 3 3 0 G protein-coupled glucose receptor regulating Gpa2 Insulin_TMD PF17870.1 OQS04406.1 - 3.8 7.7 9.2 0.9 9.7 0.0 3.1 3 0 0 3 3 3 0 Insulin receptor trans-membrane segment MHYT PF03707.16 OQS04406.1 - 4.6 7.5 9.8 1.1 9.5 0.8 3.5 3 0 0 3 3 3 0 Bacterial signalling protein N terminal repeat DUF3792 PF12670.7 OQS04406.1 - 6.2 7.0 8.0 28 4.9 0.4 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3792) DUF3290 PF11694.8 OQS04406.1 - 9.8 6.1 7.2 32 4.5 0.4 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3290) EF-hand_1 PF00036.32 OQS04408.1 - 5.4e-13 47.5 4.9 7.5e-07 28.3 0.9 2.4 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 OQS04408.1 - 4.5e-12 44.9 2.4 1.3e-05 24.8 0.5 2.4 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.6 OQS04408.1 - 1.3e-11 44.7 3.1 1.9e-11 44.3 3.1 1.3 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.6 OQS04408.1 - 8.5e-11 40.8 1.1 3.3e-06 26.3 0.1 2.4 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 OQS04408.1 - 1.5e-05 24.7 3.7 0.035 14.0 0.1 2.2 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_10 PF14788.6 OQS04408.1 - 0.0017 18.1 1.1 1.4 8.9 0.2 2.2 2 0 0 2 2 2 2 EF hand Caleosin PF05042.13 OQS04408.1 - 0.0041 17.1 0.2 0.0062 16.5 0.2 1.3 1 1 0 1 1 1 1 Caleosin related protein Melibiase_2 PF16499.5 OQS04408.1 - 0.0051 16.0 1.4 0.019 14.1 0.9 1.8 1 1 1 2 2 2 1 Alpha galactosidase A SPARC_Ca_bdg PF10591.9 OQS04408.1 - 0.014 15.7 1.1 1.9 8.9 0.1 2.1 1 1 1 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region Swm2 PF17083.5 OQS04408.1 - 0.026 14.5 0.0 0.028 14.4 0.0 1.1 1 0 0 1 1 1 0 Nucleolar protein Swm2 Glycos_trans_3N PF02885.17 OQS04408.1 - 0.073 12.9 0.0 13 5.7 0.0 2.3 2 0 0 2 2 2 0 Glycosyl transferase family, helical bundle domain CTP_transf_like PF01467.26 OQS04411.1 - 1.9e-31 109.2 0.1 1.5e-30 106.3 0.0 2.0 2 0 0 2 2 2 1 Cytidylyltransferase-like DUF4304 PF14137.6 OQS04411.1 - 0.12 12.6 0.0 0.33 11.1 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4304) DUF5639 PF18690.1 OQS04411.1 - 0.14 12.4 0.0 0.51 10.5 0.0 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF5639) RNA_pol_Rpb6 PF01192.22 OQS04412.1 - 3.8e-17 62.0 0.2 3.8e-17 62.0 0.2 1.5 2 0 0 2 2 2 1 RNA polymerase Rpb6 Ran_BP1 PF00638.18 OQS04413.1 - 1.6e-08 34.8 0.1 3.2e-08 33.8 0.1 1.5 1 0 0 1 1 1 1 RanBP1 domain NUP50 PF08911.11 OQS04413.1 - 1e-05 26.1 3.1 1e-05 26.1 3.1 6.6 4 2 0 4 4 4 1 NUP50 (Nucleoporin 50 kDa) Nucleoporin_FG2 PF15967.5 OQS04413.1 - 0.00014 20.6 51.3 0.00014 20.6 51.3 3.0 2 1 1 3 3 3 2 Nucleoporin FG repeated region B9-C2 PF07162.11 OQS04414.1 - 4.3e-43 147.4 0.0 5e-43 147.2 0.0 1.0 1 0 0 1 1 1 1 Ciliary basal body-associated, B9 protein Transglut_core3 PF13471.6 OQS04415.1 - 0.065 13.1 0.1 0.099 12.5 0.1 1.4 1 0 0 1 1 1 0 Transglutaminase-like superfamily Pkinase PF00069.25 OQS04418.1 - 1.5e-49 168.8 0.0 2.7e-49 167.9 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQS04418.1 - 4.8e-24 85.1 0.0 7.5e-24 84.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 OQS04418.1 - 4.8e-05 22.8 0.2 0.00013 21.4 0.0 1.8 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OQS04418.1 - 6.4e-05 23.0 0.1 0.00053 20.0 0.0 2.3 2 1 1 3 3 3 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 OQS04418.1 - 0.00048 19.8 0.0 0.0011 18.6 0.0 1.6 1 0 0 1 1 1 1 Choline/ethanolamine kinase EGF_2 PF07974.13 OQS04419.1 - 4.4e-20 71.7 48.7 5.9e-07 29.8 11.8 5.4 4 2 0 4 4 4 4 EGF-like domain Laminin_EGF PF00053.24 OQS04419.1 - 0.00013 22.0 20.3 0.00036 20.6 6.1 4.6 3 2 1 4 4 4 3 Laminin EGF domain EGF PF00008.27 OQS04419.1 - 0.0029 17.9 1.9 0.0029 17.9 1.9 5.9 6 0 0 6 6 6 3 EGF-like domain EGF_Tenascin PF18720.1 OQS04419.1 - 0.12 12.4 47.9 0.41 10.8 1.1 6.1 6 0 0 6 6 6 0 Tenascin EGF domain EF-hand_8 PF13833.6 OQS04420.1 - 0.041 13.7 0.1 0.1 12.4 0.1 1.7 1 0 0 1 1 1 0 EF-hand domain pair Kinesin PF00225.23 OQS04421.1 - 1.5e-102 342.9 0.2 2.8e-102 342.1 0.2 1.4 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 OQS04421.1 - 2.7e-17 63.1 0.0 9.6e-17 61.3 0.0 2.0 1 0 0 1 1 1 1 Microtubule binding DUF4600 PF15372.6 OQS04421.1 - 0.065 13.7 6.1 0.29 11.6 6.1 2.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4600) DUF2730 PF10805.8 OQS04421.1 - 0.08 13.0 6.2 0.052 13.6 1.7 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2730) RNF220 PF15926.5 OQS04421.1 - 0.13 11.9 5.7 0.022 14.4 1.7 1.7 2 0 0 2 2 2 0 E3 ubiquitin-protein ligase RNF220 DUF4407 PF14362.6 OQS04421.1 - 0.14 11.5 12.2 0.46 9.8 12.2 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Spc24 PF08286.11 OQS04421.1 - 0.23 11.7 7.9 6.2 7.1 2.1 3.3 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 APG6_N PF17675.1 OQS04421.1 - 0.26 11.8 27.3 0.11 13.1 5.2 2.9 3 0 0 3 3 2 0 Apg6 coiled-coil region HALZ PF02183.18 OQS04421.1 - 0.56 10.5 9.0 0.62 10.3 0.8 3.1 2 0 0 2 2 2 0 Homeobox associated leucine zipper YabA PF06156.13 OQS04421.1 - 2.2 8.9 12.5 1 10.0 3.6 3.6 2 1 0 3 3 3 0 Initiation control protein YabA GAS PF13851.6 OQS04421.1 - 6.5 6.1 25.0 0.3 10.4 10.2 2.8 3 0 0 3 3 3 0 Growth-arrest specific micro-tubule binding CCDC-167 PF15188.6 OQS04421.1 - 6.9 7.1 8.7 25 5.3 1.7 3.0 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 PolyA_pol PF01743.20 OQS04422.1 - 5.5e-29 101.2 0.1 1.1e-28 100.2 0.1 1.6 1 0 0 1 1 1 1 Poly A polymerase head domain PolyA_pol_RNAbd PF12627.7 OQS04422.1 - 8.1e-06 25.5 0.0 1.9e-05 24.3 0.0 1.6 1 0 0 1 1 1 1 Probable RNA and SrmB- binding site of polymerase A PT PF04886.12 OQS04422.1 - 0.00076 19.0 67.9 0.00099 18.6 23.6 4.4 1 1 3 4 4 4 3 PT repeat Glyco_hydro_17 PF00332.18 OQS04422.1 - 0.058 13.0 4.9 0.13 11.8 3.8 2.1 2 0 0 2 2 2 0 Glycosyl hydrolases family 17 TMEM154 PF15102.6 OQS04423.1 - 1.6e-05 24.8 0.0 4e-05 23.6 0.0 1.6 1 0 0 1 1 1 1 TMEM154 protein family TMEM51 PF15345.6 OQS04423.1 - 0.0015 18.4 0.0 0.0031 17.4 0.0 1.5 1 0 0 1 1 1 1 Transmembrane protein 51 SKG6 PF08693.10 OQS04423.1 - 0.011 15.1 4.3 0.025 14.0 4.3 1.6 1 0 0 1 1 1 0 Transmembrane alpha-helix domain CD34_antigen PF06365.12 OQS04423.1 - 0.012 15.2 0.0 0.02 14.5 0.0 1.3 1 0 0 1 1 1 0 CD34/Podocalyxin family SARAF PF06682.12 OQS04423.1 - 0.014 15.1 0.0 0.027 14.1 0.0 1.4 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis EphA2_TM PF14575.6 OQS04423.1 - 0.014 16.3 0.0 0.031 15.1 0.0 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF2207 PF09972.9 OQS04423.1 - 0.033 13.0 0.0 0.046 12.5 0.0 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF5305 PF17231.2 OQS04423.1 - 0.037 13.4 0.2 0.098 12.0 0.2 1.5 1 1 0 1 1 1 0 Family of unknown function (DUF5305) Syndecan PF01034.20 OQS04423.1 - 0.073 13.0 0.0 0.16 11.9 0.0 1.5 1 0 0 1 1 1 0 Syndecan domain Podoplanin PF05808.11 OQS04423.1 - 1.4 9.0 4.7 2.8 8.0 3.9 1.9 1 1 0 1 1 1 0 Podoplanin Voltage_CLC PF00654.20 OQS04424.1 - 4.4e-70 236.7 22.7 4.4e-70 236.7 22.7 1.5 1 1 1 2 2 2 1 Voltage gated chloride channel CBS PF00571.28 OQS04424.1 - 5.4e-05 23.6 0.0 0.36 11.3 0.0 2.5 2 0 0 2 2 2 2 CBS domain PRCC PF10253.9 OQS04425.1 - 0.018 15.8 5.0 0.027 15.2 5.0 1.3 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting Glyco_hydro_17 PF00332.18 OQS04425.1 - 0.093 12.3 6.6 0.033 13.8 3.0 2.1 3 0 0 3 3 3 0 Glycosyl hydrolases family 17 Orf78 PF06024.12 OQS04425.1 - 0.17 12.2 0.0 0.33 11.3 0.0 1.5 1 0 0 1 1 1 0 Orf78 (ac78) Trypan_PARP PF05887.11 OQS04425.1 - 5.4 7.0 20.3 15 5.5 20.3 1.8 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Sulfotransfer_1 PF00685.27 OQS04426.1 - 5.2e-35 121.2 0.0 7e-35 120.8 0.0 1.1 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 OQS04426.1 - 2.8e-07 31.1 0.1 2.7e-05 24.7 0.2 3.0 1 1 1 2 2 2 1 Sulfotransferase family Cna_B PF05738.13 OQS04427.1 - 0.69 10.5 3.0 0.58 10.7 0.5 2.1 2 0 0 2 2 2 0 Cna protein B-type domain Carb_kinase PF01256.17 OQS04428.1 - 1.5e-53 181.8 0.1 2e-53 181.4 0.1 1.1 1 0 0 1 1 1 1 Carbohydrate kinase HK PF02110.15 OQS04428.1 - 7.7e-05 22.2 0.0 0.00011 21.7 0.0 1.2 1 0 0 1 1 1 1 Hydroxyethylthiazole kinase family 4HBT PF03061.22 OQS04429.1 - 6.8e-15 55.2 0.1 4.2e-06 27.0 0.0 2.9 3 0 0 3 3 3 2 Thioesterase superfamily MaoC_dehydratas PF01575.19 OQS04429.1 - 0.065 12.8 0.0 11 5.6 0.0 2.2 2 0 0 2 2 2 0 MaoC like domain COX5B PF01215.19 OQS04431.1 - 5.2e-14 52.0 0.0 5.8e-14 51.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Vb NifT PF06988.11 OQS04431.1 - 0.081 12.7 0.0 0.17 11.7 0.0 1.5 1 0 0 1 1 1 0 NifT/FixU protein DUF5624 PF18538.1 OQS04431.1 - 0.13 12.4 0.0 0.17 12.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5624) Methyltransf_21 PF05050.12 OQS04432.1 - 0.0025 17.9 0.1 0.02 14.9 0.1 2.3 2 1 1 3 3 3 1 Methyltransferase FkbM domain TPR_12 PF13424.6 OQS04432.1 - 0.078 13.3 0.2 23 5.4 0.0 2.6 2 1 1 3 3 3 0 Tetratricopeptide repeat RWP-RK PF02042.15 OQS04433.1 - 5.4e-19 67.9 0.1 9.9e-19 67.1 0.1 1.5 1 0 0 1 1 1 1 RWP-RK domain Myb_DNA-binding PF00249.31 OQS04433.1 - 9.6e-12 44.9 1.0 1.8e-11 44.0 0.1 2.0 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OQS04433.1 - 0.0063 16.7 0.0 0.014 15.6 0.0 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain PRT_C PF08372.10 OQS04433.1 - 0.028 14.2 0.0 0.44 10.3 0.0 2.4 2 0 0 2 2 2 0 Plant phosphoribosyltransferase C-terminal DUF1445 PF07286.12 OQS04434.1 - 4.3e-66 221.3 0.0 5.4e-66 220.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1445) CAF1A PF12253.8 OQS04435.1 - 1e-20 73.6 3.2 1e-20 73.6 3.2 2.7 3 0 0 3 3 3 1 Chromatin assembly factor 1 subunit A Glyco_hydro_52 PF03512.13 OQS04435.1 - 0.046 12.7 1.2 0.086 11.8 0.6 1.7 2 0 0 2 2 2 0 Glycosyl hydrolase family 52 DUF3537 PF12056.8 OQS04435.1 - 0.4 9.5 2.2 0.64 8.8 2.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3537) DUF4554 PF15091.6 OQS04435.1 - 1.9 7.3 5.7 4.4 6.1 5.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4554) Mito_carr PF00153.27 OQS04436.1 - 5.1e-42 141.7 9.0 3e-15 55.9 0.0 3.6 3 1 0 3 3 3 3 Mitochondrial carrier protein ABC_tran PF00005.27 OQS04437.1 - 3.1e-15 56.9 0.0 4.2e-15 56.5 0.0 1.2 1 0 0 1 1 1 1 ABC transporter DUF2075 PF09848.9 OQS04437.1 - 0.0074 15.6 0.0 0.0098 15.2 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_29 PF13555.6 OQS04437.1 - 0.009 15.7 0.2 0.02 14.6 0.2 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.6 OQS04437.1 - 0.022 15.1 0.4 0.035 14.5 0.1 1.6 2 1 0 2 2 2 0 AAA ATPase domain Zeta_toxin PF06414.12 OQS04437.1 - 0.029 13.7 0.1 0.049 12.9 0.1 1.3 1 0 0 1 1 1 0 Zeta toxin RsgA_GTPase PF03193.16 OQS04437.1 - 0.047 13.6 0.1 0.072 13.0 0.1 1.3 1 0 0 1 1 1 0 RsgA GTPase DUF815 PF05673.13 OQS04437.1 - 0.085 12.0 0.0 0.13 11.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_22 PF13401.6 OQS04437.1 - 0.11 12.8 0.0 0.17 12.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 OQS04437.1 - 0.13 12.3 0.1 0.23 11.6 0.1 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase Roc PF08477.13 OQS04437.1 - 0.15 12.3 0.0 0.27 11.4 0.0 1.5 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase Ploopntkinase3 PF18751.1 OQS04437.1 - 0.15 12.0 0.1 0.25 11.2 0.1 1.3 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 AAA_18 PF13238.6 OQS04437.1 - 0.18 12.4 0.0 0.27 11.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain ABC2_membrane PF01061.24 OQS04438.1 - 2.1e-34 118.8 23.8 3.8e-34 117.9 23.8 1.4 1 0 0 1 1 1 1 ABC-2 type transporter PDR_CDR PF06422.12 OQS04438.1 - 1.2e-05 25.1 0.7 1.2e-05 25.1 0.7 2.3 2 0 0 2 2 2 1 CDR ABC transporter PDR_assoc PF08370.11 OQS04438.1 - 0.12 12.1 0.3 0.12 12.1 0.3 3.9 4 1 1 5 5 5 0 Plant PDR ABC transporter associated DEK_C PF08766.11 OQS04439.1 - 0.0035 17.2 0.8 0.0091 15.9 0.8 1.8 1 0 0 1 1 1 1 DEK C terminal domain Hid1 PF12722.7 OQS04439.1 - 0.23 9.5 17.8 0.3 9.1 17.8 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein GREB1 PF15782.5 OQS04439.1 - 2 5.4 14.2 2.5 5.1 14.2 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Macoilin PF09726.9 OQS04439.1 - 2.1 6.8 21.3 2.5 6.6 21.3 1.1 1 0 0 1 1 1 0 Macoilin family CiPC PF15800.5 OQS04439.1 - 2.1 8.0 22.7 3.9 7.1 22.7 1.5 1 0 0 1 1 1 0 Clock interacting protein circadian Pap_E4 PF02711.14 OQS04439.1 - 2.7 9.0 28.3 1.2 10.2 8.6 3.9 2 1 2 4 4 4 0 E4 protein PA26 PF04636.13 OQS04439.1 - 4 6.3 8.4 5.5 5.8 8.4 1.2 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) BUD22 PF09073.10 OQS04439.1 - 5 6.3 41.1 1.4 8.2 32.0 2.2 2 0 0 2 2 2 0 BUD22 DUF4551 PF15087.6 OQS04439.1 - 6.2 5.5 21.8 8.2 5.1 21.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) TBP PF00352.21 OQS04440.1 - 1e-46 156.8 0.0 9.3e-23 80.0 0.0 2.0 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) HEAT PF02985.22 OQS04441.1 - 9.8e-10 37.9 22.7 0.58 10.6 0.0 11.6 13 0 0 13 13 13 3 HEAT repeat HEAT_2 PF13646.6 OQS04441.1 - 5.7e-08 33.1 7.9 0.013 15.8 0.1 6.8 5 2 1 6 6 6 2 HEAT repeats Vac14_Fab1_bd PF12755.7 OQS04441.1 - 8.7e-07 29.5 1.6 19 5.9 0.0 6.3 5 1 1 6 6 6 0 Vacuolar 14 Fab1-binding region Cnd1 PF12717.7 OQS04441.1 - 2.6e-06 27.6 13.9 0.23 11.5 0.2 6.3 3 2 3 6 6 6 2 non-SMC mitotic condensation complex subunit 1 CLASP_N PF12348.8 OQS04441.1 - 6.2e-05 22.7 2.4 0.15 11.6 0.0 4.4 4 1 1 5 5 5 2 CLASP N terminal HEAT_EZ PF13513.6 OQS04441.1 - 7.2e-05 23.2 18.6 0.014 15.9 0.0 7.9 8 2 2 10 10 9 1 HEAT-like repeat TIP120 PF08623.10 OQS04441.1 - 0.0013 18.6 1.2 4.1 7.2 0.1 3.9 2 2 2 4 4 4 2 TATA-binding protein interacting (TIP20) Hid1 PF12722.7 OQS04441.1 - 0.018 13.2 0.3 0.24 9.5 0.0 2.1 2 0 0 2 2 2 0 High-temperature-induced dauer-formation protein Dopey_N PF04118.14 OQS04441.1 - 0.029 13.5 0.3 0.28 10.3 0.1 2.6 2 0 0 2 2 2 0 Dopey, N-terminal ParcG PF10274.9 OQS04441.1 - 0.042 14.0 0.9 3.3 7.8 0.2 3.0 2 1 0 2 2 2 0 Parkin co-regulated protein RasGEF_N_2 PF14663.6 OQS04441.1 - 0.28 11.6 1.3 59 4.1 0.0 4.5 4 0 0 4 4 4 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain PRA1 PF03208.19 OQS04442.1 - 6.4e-22 77.7 1.0 7.3e-22 77.5 1.0 1.1 1 0 0 1 1 1 1 PRA1 family protein Erv26 PF04148.13 OQS04442.1 - 0.019 14.8 1.5 0.029 14.2 1.5 1.3 1 0 0 1 1 1 0 Transmembrane adaptor Erv26 TadE PF07811.12 OQS04442.1 - 0.074 13.3 0.5 0.2 11.9 0.5 1.8 1 0 0 1 1 1 0 TadE-like protein RHD3 PF05879.12 OQS04442.1 - 0.32 9.1 0.3 0.39 8.8 0.3 1.1 1 0 0 1 1 1 0 Root hair defective 3 GTP-binding protein (RHD3) CoA_transf_3 PF02515.17 OQS04443.1 - 2.3e-44 152.0 0.1 5e-44 150.9 0.1 1.4 1 1 0 1 1 1 1 CoA-transferase family III Peptidase_A22B PF04258.13 OQS04444.1 - 6.2e-90 301.6 3.7 8.6e-90 301.1 3.7 1.1 1 0 0 1 1 1 1 Signal peptide peptidase DUF4149 PF13664.6 OQS04444.1 - 8.5 6.8 10.3 0.35 11.2 1.4 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF4149) Polyketide_cyc2 PF10604.9 OQS04445.1 - 0.0017 18.6 0.0 0.002 18.4 0.0 1.2 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport tRNA-synt_1b PF00579.25 OQS04446.1 - 9.6e-60 202.4 0.0 1.5e-59 201.7 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) Apolipoprotein PF01442.18 OQS04446.1 - 0.0069 16.3 1.7 0.015 15.2 1.7 1.6 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain CENP-B_N PF04218.13 OQS04446.1 - 0.086 12.5 0.4 10 5.8 0.1 3.0 3 0 0 3 3 3 0 CENP-B N-terminal DNA-binding domain ARGLU PF15346.6 OQS04446.1 - 0.14 12.0 7.4 0.24 11.2 7.4 1.4 1 0 0 1 1 1 0 Arginine and glutamate-rich 1 DUF2009 PF09418.10 OQS04447.1 - 4.5e-194 645.7 0.0 5.5e-194 645.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2009) zf-B_box PF00643.24 OQS04447.1 - 0.0021 18.2 14.6 0.0032 17.6 13.2 1.9 2 0 0 2 2 2 1 B-box zinc finger CEBP_ZZ PF16366.5 OQS04447.1 - 0.013 15.8 10.5 0.027 14.7 10.5 1.4 1 0 0 1 1 1 0 Cytoplasmic polyadenylation element-binding protein ZZ domain SHIPPO-rpt PF07004.12 OQS04448.1 - 1.1e-10 41.9 48.0 0.49 11.4 0.2 11.2 11 0 0 11 11 11 7 Sperm-tail PG-rich repeat Metallophos PF00149.28 OQS04449.1 - 1.1e-31 111.0 0.1 1.7e-31 110.3 0.1 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase EF-hand_7 PF13499.6 OQS04449.1 - 0.0026 18.2 0.2 0.011 16.2 0.2 2.1 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.6 OQS04449.1 - 0.034 14.0 0.1 0.081 12.8 0.1 1.7 1 0 0 1 1 1 0 EF-hand domain pair CLZ PF16526.5 OQS04450.1 - 0.013 15.9 3.2 0.013 15.9 3.2 3.9 2 1 2 4 4 4 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels HTH_10 PF04967.12 OQS04450.1 - 0.047 13.5 0.1 0.13 12.1 0.1 1.8 1 0 0 1 1 1 0 HTH DNA binding domain Muted PF14942.6 OQS04450.1 - 0.96 9.8 17.9 0.52 10.6 13.6 2.5 2 1 1 3 3 3 0 Organelle biogenesis, Muted-like protein DUF1664 PF07889.12 OQS04450.1 - 1.1 9.4 17.1 0.039 14.0 1.5 3.0 3 1 1 4 4 4 0 Protein of unknown function (DUF1664) DUF948 PF06103.11 OQS04450.1 - 2 8.7 7.0 0.6 10.4 2.0 2.6 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) KIP1 PF07765.12 OQS04450.1 - 3.5 7.8 10.0 9.4 6.4 0.6 3.2 2 1 1 3 3 3 0 KIP1-like protein Remorin_C PF03763.13 OQS04450.1 - 5.3 7.0 14.6 0.16 11.8 3.4 2.6 1 1 1 2 2 2 0 Remorin, C-terminal region DUF4407 PF14362.6 OQS04450.1 - 6.8 5.9 19.8 5.8 6.2 3.3 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) PP2C PF00481.21 OQS04451.1 - 1.7e-43 149.1 0.0 2.1e-43 148.8 0.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 OQS04451.1 - 2.9e-08 33.9 0.2 1.4e-05 25.1 0.0 2.1 2 0 0 2 2 2 2 Stage II sporulation protein E (SpoIIE) GGACT PF06094.12 OQS04452.1 - 1.9e-18 67.2 0.2 2.8e-18 66.7 0.2 1.4 1 1 0 1 1 1 1 Gamma-glutamyl cyclotransferase, AIG2-like AIG2_2 PF13772.6 OQS04452.1 - 4.8e-06 26.9 0.3 1.1e-05 25.7 0.1 1.7 2 0 0 2 2 2 1 AIG2-like family VHL_C PF17211.3 OQS04452.1 - 0.054 13.5 0.6 9.4 6.3 0.2 2.3 2 0 0 2 2 2 0 VHL box domain 2OG-FeII_Oxy_3 PF13640.6 OQS04453.1 - 9.1e-16 58.5 0.0 1.4e-15 57.9 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.6 OQS04453.1 - 2.3e-08 34.6 0.0 3.7e-08 33.9 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily ECH_1 PF00378.20 OQS04454.1 - 2.9e-83 279.0 1.4 3.3e-83 278.8 1.4 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 OQS04454.1 - 7e-36 124.4 1.6 2.7e-33 115.9 1.0 2.0 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase Peptidase_S49 PF01343.18 OQS04454.1 - 0.038 14.0 0.2 0.33 10.9 0.0 2.3 2 0 0 2 2 2 0 Peptidase family S49 IQ PF00612.27 OQS04455.1 - 0.16 11.9 0.1 0.16 11.9 0.1 2.1 2 0 0 2 2 2 0 IQ calmodulin-binding motif Mntp PF02659.15 OQS04455.1 - 0.32 10.8 6.1 0.16 11.7 2.1 2.5 2 1 0 2 2 2 0 Putative manganese efflux pump OHCU_decarbox PF09349.10 OQS04456.1 - 1.7e-12 48.1 1.1 1.9e-12 47.9 1.1 1.0 1 0 0 1 1 1 1 OHCU decarboxylase PLAC8 PF04749.17 OQS04458.1 - 1.8e-16 60.9 9.8 2.4e-16 60.6 9.8 1.1 1 0 0 1 1 1 1 PLAC8 family Pkinase PF00069.25 OQS04459.1 - 1.2e-45 155.9 0.0 1.6e-45 155.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQS04459.1 - 5.6e-30 104.5 0.0 7.2e-30 104.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OQS04459.1 - 0.00047 19.0 0.1 0.00063 18.6 0.1 1.1 1 0 0 1 1 1 1 Fungal protein kinase RIO1 PF01163.22 OQS04459.1 - 0.0013 18.4 0.1 0.0019 17.8 0.1 1.2 1 0 0 1 1 1 1 RIO1 family Kinase-like PF14531.6 OQS04459.1 - 0.002 17.5 0.0 0.0028 17.0 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 OQS04459.1 - 0.0022 17.0 0.0 0.0032 16.5 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 OQS04459.1 - 0.018 14.4 0.3 0.026 13.9 0.3 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_Tyr PF07714.17 OQS04460.1 - 1.6e-38 132.5 0.0 2e-38 132.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OQS04460.1 - 1.4e-30 106.5 0.0 1.9e-30 106.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 OQS04460.1 - 0.029 13.7 0.0 0.047 13.1 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family LRR19-TM PF15176.6 OQS04460.1 - 0.073 13.1 0.0 0.17 11.9 0.0 1.5 1 0 0 1 1 1 0 Leucine-rich repeat family 19 TM domain Sugar_tr PF00083.24 OQS04461.1 - 7.4e-41 140.4 27.1 5e-25 88.3 5.4 2.0 1 1 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 OQS04461.1 - 3.1e-28 98.7 57.1 5.2e-25 88.1 32.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 OQS04461.1 - 0.0016 17.1 5.3 0.0016 17.1 5.3 3.0 2 1 1 3 3 3 1 MFS/sugar transport protein DUF4293 PF14126.6 OQS04461.1 - 5.7 7.2 7.8 2.9 8.1 3.7 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4293) RhoGAP PF00620.27 OQS04462.1 - 2.1e-14 53.6 0.0 3.6e-14 52.9 0.0 1.4 1 0 0 1 1 1 1 RhoGAP domain PH PF00169.29 OQS04462.1 - 2e-05 25.0 0.0 5.8e-05 23.5 0.0 1.9 1 0 0 1 1 1 1 PH domain UPF0552 PF10574.9 OQS04462.1 - 0.0037 16.7 0.0 0.0088 15.4 0.0 1.6 1 0 0 1 1 1 1 Arp2/3-interacting proteins Arpin PH_8 PF15409.6 OQS04462.1 - 0.0037 17.5 0.0 0.081 13.2 0.0 2.4 2 0 0 2 2 2 1 Pleckstrin homology domain PolyA_pol PF01743.20 OQS04463.1 - 7.3e-26 91.1 0.0 1.3e-25 90.2 0.0 1.4 1 0 0 1 1 1 1 Poly A polymerase head domain PolyA_pol_RNAbd PF12627.7 OQS04463.1 - 2.6e-13 49.5 0.1 5.7e-13 48.4 0.1 1.5 1 0 0 1 1 1 1 Probable RNA and SrmB- binding site of polymerase A DUF2605 PF10792.9 OQS04463.1 - 0.053 13.4 0.1 0.18 11.8 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2605) RPM2 PF08579.11 OQS04463.1 - 0.11 12.9 0.8 0.24 11.8 0.8 1.5 1 0 0 1 1 1 0 Mitochondrial ribonuclease P subunit (RPM2) PCO_ADO PF07847.12 OQS04464.1 - 1.2e-44 152.2 0.0 2.3e-44 151.3 0.0 1.4 1 0 0 1 1 1 1 PCO_ADO Cupin_2 PF07883.11 OQS04464.1 - 0.0083 15.8 0.0 0.026 14.2 0.0 1.9 2 0 0 2 2 2 1 Cupin domain Cupin_1 PF00190.22 OQS04464.1 - 0.055 13.1 0.1 1.9 8.1 0.0 3.1 3 0 0 3 3 3 0 Cupin Nucleoporin_N PF08801.11 OQS04465.1 - 2.8e-30 105.4 0.0 1.3e-28 99.9 0.0 2.3 1 1 0 1 1 1 1 Nup133 N terminal like Nucleoporin_C PF03177.14 OQS04465.1 - 0.0032 16.3 0.2 0.053 12.3 0.2 2.5 1 1 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal Tubulin PF00091.25 OQS04466.1 - 7.1e-62 209.1 0.0 7.9e-62 209.0 0.0 1.0 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_3 PF14881.6 OQS04466.1 - 0.0023 17.7 0.0 0.0032 17.2 0.0 1.2 1 0 0 1 1 1 1 Tubulin domain Tubulin PF00091.25 OQS04467.1 - 2.5e-65 220.4 0.0 3.4e-65 220.0 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 OQS04467.1 - 2.2e-49 166.8 0.0 3.3e-49 166.2 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 OQS04467.1 - 0.0046 16.7 0.0 0.015 15.0 0.0 1.8 2 0 0 2 2 2 1 Tubulin domain ArfGap PF01412.18 OQS04468.1 - 4.7e-35 120.2 0.2 8.9e-35 119.3 0.2 1.4 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf C2 PF00168.30 OQS04468.1 - 1.3e-18 67.2 0.0 2.2e-18 66.4 0.0 1.4 1 0 0 1 1 1 1 C2 domain ATG_C PF09333.11 OQS04468.1 - 8.8e-05 22.8 0.0 0.00016 21.9 0.0 1.4 1 0 0 1 1 1 1 Autophagy-related protein C terminal domain Pkinase PF00069.25 OQS04469.1 - 1.5e-39 136.0 0.0 3e-20 72.7 0.0 2.6 2 0 0 2 2 2 2 Protein kinase domain Kelch_5 PF13854.6 OQS04469.1 - 3.8e-23 81.0 1.0 7.5e-05 22.6 0.0 6.6 6 0 0 6 6 6 5 Kelch motif Inv-AAD PF18785.1 OQS04469.1 - 3.5e-22 78.6 4.4 1.2e-21 77.0 1.9 2.8 2 1 0 2 2 2 1 Invertebrate-AID/APOBEC-deaminase Kelch_4 PF13418.6 OQS04469.1 - 1.5e-21 76.1 7.1 3.4e-06 26.9 0.1 6.5 6 0 0 6 6 6 4 Galactose oxidase, central domain Ank_4 PF13637.6 OQS04469.1 - 1.9e-20 73.0 0.1 7.2e-08 32.8 0.0 3.5 1 1 2 3 3 3 3 Ankyrin repeats (many copies) dCMP_cyt_deam_1 PF00383.23 OQS04469.1 - 6e-18 64.6 1.1 6e-18 64.6 1.1 2.2 2 0 0 2 2 2 1 Cytidine and deoxycytidylate deaminase zinc-binding region Ank_2 PF12796.7 OQS04469.1 - 6.8e-17 61.8 0.0 2.4e-16 60.1 0.0 2.0 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Pkinase_Tyr PF07714.17 OQS04469.1 - 1.9e-14 53.6 0.1 6.3e-08 32.2 0.0 3.0 3 0 0 3 3 3 2 Protein tyrosine kinase Kelch_6 PF13964.6 OQS04469.1 - 2.6e-14 52.9 7.7 0.13 12.6 0.1 6.7 6 0 0 6 6 6 5 Kelch motif Kelch_3 PF13415.6 OQS04469.1 - 3.9e-14 52.5 11.4 0.00096 19.4 0.1 6.7 6 0 0 6 6 6 3 Galactose oxidase, central domain Ank PF00023.30 OQS04469.1 - 1.2e-11 44.5 0.1 0.0037 17.6 0.0 4.1 3 0 0 3 3 3 3 Ankyrin repeat Kelch_1 PF01344.25 OQS04469.1 - 7e-11 41.5 2.0 0.0045 16.5 0.1 5.9 6 0 0 6 6 6 3 Kelch motif Ank_5 PF13857.6 OQS04469.1 - 6.2e-10 39.1 0.2 4.8e-05 23.6 0.1 3.0 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQS04469.1 - 2.1e-09 36.8 0.0 0.063 13.9 0.0 4.2 3 0 0 3 3 3 2 Ankyrin repeat Kelch_2 PF07646.15 OQS04469.1 - 3.5e-07 29.9 5.2 0.11 12.6 0.0 6.2 6 0 0 6 6 6 2 Kelch motif MafB19-deam PF14437.6 OQS04469.1 - 2.8e-05 23.9 2.1 5.7e-05 22.9 2.1 1.5 1 0 0 1 1 1 1 MafB19-like deaminase Kelch_5 PF13854.6 OQS04470.1 - 1.3e-05 25.1 0.2 0.013 15.5 0.0 2.5 2 0 0 2 2 2 2 Kelch motif HARP PF07443.13 OQS04470.1 - 0.0038 16.8 0.0 0.0092 15.6 0.0 1.6 2 0 0 2 2 2 1 HepA-related protein (HARP) LtrA PF06772.11 OQS04470.1 - 0.17 11.1 1.7 15 4.7 0.2 2.8 1 1 2 3 3 3 0 Bacterial low temperature requirement A protein (LtrA) CS PF04969.16 OQS04471.1 - 2.4e-16 60.5 0.6 5.6e-16 59.3 0.0 1.9 2 0 0 2 2 2 1 CS domain Nudc_N PF14050.6 OQS04471.1 - 3.6e-13 49.3 0.1 1e-12 47.8 0.1 1.8 1 0 0 1 1 1 1 N-terminal conserved domain of Nudc. RNF220 PF15926.5 OQS04471.1 - 0.0031 17.2 0.5 0.0031 17.2 0.5 1.5 2 0 0 2 2 2 1 E3 ubiquitin-protein ligase RNF220 MLANA PF14991.6 OQS04471.1 - 0.13 12.5 0.9 0.31 11.3 0.9 1.6 1 0 0 1 1 1 0 Protein melan-A D5_N PF08706.11 OQS04471.1 - 1.6 9.0 6.4 2.9 8.2 6.4 1.5 1 1 0 1 1 1 0 D5 N terminal like Jak1_Phl PF17887.1 OQS04471.1 - 2.2 8.2 7.2 3 7.8 3.2 2.3 2 0 0 2 2 2 0 Jak1 pleckstrin homology-like domain Presenilin PF01080.17 OQS04471.1 - 6.1 5.5 4.6 8.8 5.0 4.6 1.2 1 0 0 1 1 1 0 Presenilin DUF4337 PF14235.6 OQS04471.1 - 7.1 6.7 9.4 13 5.8 9.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) Lipase_3 PF01764.25 OQS04473.1 - 2.6e-28 98.7 0.0 7.8e-28 97.1 0.0 1.8 1 1 0 1 1 1 1 Lipase (class 3) DUF2974 PF11187.8 OQS04473.1 - 8.6e-06 25.5 0.0 0.012 15.2 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF2974) Hydrolase_4 PF12146.8 OQS04473.1 - 0.00021 20.6 0.0 0.00055 19.3 0.0 1.6 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Esterase PF00756.20 OQS04473.1 - 0.0016 18.2 0.0 0.0033 17.1 0.0 1.4 1 0 0 1 1 1 1 Putative esterase Abhydrolase_6 PF12697.7 OQS04473.1 - 0.01 16.4 0.0 0.082 13.5 0.0 2.4 2 0 0 2 2 2 0 Alpha/beta hydrolase family PGAP1 PF07819.13 OQS04473.1 - 0.088 12.5 0.0 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein DUF900 PF05990.12 OQS04473.1 - 0.15 11.6 0.0 0.24 10.9 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) DUF5367 PF17329.2 OQS04473.1 - 1 9.5 7.9 0.26 11.4 2.3 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF5367) Ank PF00023.30 OQS04474.1 - 1.4e-06 28.4 0.4 0.00014 22.1 0.0 2.3 1 1 1 2 2 2 2 Ankyrin repeat Ank_3 PF13606.6 OQS04474.1 - 4.2e-06 26.7 0.3 0.001 19.3 0.0 2.7 2 1 1 3 3 3 2 Ankyrin repeat Ank_2 PF12796.7 OQS04474.1 - 7.9e-05 23.2 0.0 0.0025 18.4 0.0 2.1 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OQS04474.1 - 0.00043 20.5 0.0 0.018 15.3 0.0 2.2 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Pyridoxal_deC PF00282.19 OQS04475.1 - 7.1e-73 245.5 0.0 1e-72 244.9 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Hormone_2 PF00123.20 OQS04477.1 - 0.13 12.2 0.0 0.29 11.1 0.0 1.6 1 0 0 1 1 1 0 Peptide hormone Ank_4 PF13637.6 OQS04478.1 - 9.5e-09 35.6 0.0 3.4e-08 33.9 0.0 1.9 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 OQS04478.1 - 1.8e-06 28.4 0.1 1.1e-05 25.9 0.0 2.2 2 1 1 3 3 3 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OQS04478.1 - 0.00083 19.6 0.1 0.0056 17.0 0.0 2.4 2 1 1 3 3 3 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQS04478.1 - 0.0027 18.1 0.0 0.037 14.6 0.0 2.6 2 0 0 2 2 2 1 Ankyrin repeat Ank PF00023.30 OQS04478.1 - 0.033 14.6 0.0 0.095 13.2 0.0 1.8 1 0 0 1 1 1 0 Ankyrin repeat Cellulase PF00150.18 OQS04479.1 - 1.6e-06 27.7 5.4 2.5e-06 27.1 5.4 1.3 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) zf-RING_2 PF13639.6 OQS04480.1 - 4.8e-12 46.0 9.8 7.7e-12 45.3 9.8 1.4 1 0 0 1 1 1 1 Ring finger domain PX PF00787.24 OQS04480.1 - 1.1e-09 38.2 1.3 1.6e-09 37.8 1.3 1.2 1 0 0 1 1 1 1 PX domain zf-C3HC4_2 PF13923.6 OQS04480.1 - 1.8e-08 34.1 8.7 3e-08 33.4 8.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 OQS04480.1 - 7.5e-08 32.1 9.2 1.2e-07 31.5 9.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 OQS04480.1 - 3e-07 30.6 12.8 1.1e-06 28.8 12.8 1.9 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_11 PF17123.5 OQS04480.1 - 2.7e-06 27.0 7.6 5.4e-06 26.0 7.6 1.5 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_UBOX PF13445.6 OQS04480.1 - 3e-05 24.0 7.4 6.3e-05 22.9 7.4 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 OQS04480.1 - 4.8e-05 23.2 7.6 7.4e-05 22.6 7.6 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 OQS04480.1 - 0.00011 22.0 8.8 0.00017 21.4 8.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 OQS04480.1 - 0.00044 20.2 3.9 0.0011 18.9 3.9 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.6 OQS04480.1 - 0.026 14.4 9.4 0.047 13.6 9.4 1.5 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 OQS04480.1 - 0.039 14.1 6.7 0.13 12.5 6.7 1.8 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING RINGv PF12906.7 OQS04480.1 - 0.048 13.8 6.8 0.13 12.4 6.8 1.7 1 1 0 1 1 1 0 RING-variant domain zf-RING_4 PF14570.6 OQS04480.1 - 0.079 12.8 4.2 0.16 11.8 4.2 1.5 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain zinc_ribbon_16 PF17034.5 OQS04480.1 - 0.2 11.9 7.3 0.33 11.2 7.3 1.4 1 1 0 1 1 1 0 Zinc-ribbon like family FANCL_C PF11793.8 OQS04480.1 - 1.2 9.3 9.7 7.3 6.8 9.7 2.3 1 1 0 1 1 1 0 FANCL C-terminal domain DUF4807 PF16065.5 OQS04481.1 - 1.3e-09 37.8 1.4 2.1e-09 37.1 1.4 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4807) TPR_MalT PF17874.1 OQS04481.1 - 1.1e-05 25.0 1.8 1.3e-05 24.8 1.8 1.1 1 0 0 1 1 1 1 MalT-like TPR region DUF2175 PF09943.9 OQS04481.1 - 0.18 12.1 1.4 0.31 11.3 1.4 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2175) Mtc PF03820.17 OQS04486.1 - 1.1e-104 349.9 0.0 1.2e-104 349.7 0.0 1.0 1 0 0 1 1 1 1 Tricarboxylate carrier VPS9 PF02204.18 OQS04487.1 - 1e-05 25.7 0.6 3e-05 24.2 0.2 2.0 2 0 0 2 2 2 1 Vacuolar sorting protein 9 (VPS9) domain AAA_34 PF13872.6 OQS04488.1 - 2.6e-118 394.3 0.0 5.6e-118 393.2 0.0 1.6 1 0 0 1 1 1 1 P-loop containing NTP hydrolase pore-1 Helicase_C_4 PF13871.6 OQS04488.1 - 1.4e-99 333.2 0.0 2.2e-99 332.6 0.0 1.3 1 0 0 1 1 1 1 C-terminal domain on Strawberry notch homologue ResIII PF04851.15 OQS04488.1 - 0.0064 16.5 0.0 0.015 15.3 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF4709 PF15821.5 OQS04488.1 - 0.042 14.1 0.0 0.13 12.6 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4709) Helicase_C PF00271.31 OQS04488.1 - 0.083 13.2 0.1 0.21 12.0 0.1 1.7 1 0 0 1 1 1 0 Helicase conserved C-terminal domain SK_channel PF03530.14 OQS04488.1 - 0.098 12.6 0.1 0.28 11.2 0.1 1.8 1 0 0 1 1 1 0 Calcium-activated SK potassium channel GOLD_2 PF13897.6 OQS04488.1 - 0.15 12.5 0.2 0.41 11.1 0.2 1.7 1 0 0 1 1 1 0 Golgi-dynamics membrane-trafficking WD40 PF00400.32 OQS04489.1 - 1.4e-49 165.0 20.0 2.2e-07 31.4 0.0 7.6 7 1 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OQS04489.1 - 7e-14 51.9 0.1 0.0045 17.2 0.0 5.2 2 2 2 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 OQS04489.1 - 0.00035 19.6 0.4 0.11 11.4 0.1 2.4 2 0 0 2 2 2 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 OQS04489.1 - 0.0035 16.1 0.5 1.2 7.7 0.0 3.8 1 1 3 4 4 4 1 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 OQS04489.1 - 0.0068 15.2 0.0 0.043 12.5 0.0 2.1 2 1 0 2 2 2 1 Nup133 N terminal like Pkinase PF00069.25 OQS04490.1 - 5.8e-28 98.0 0.0 7.8e-28 97.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQS04490.1 - 1.7e-16 60.3 0.0 2.1e-16 60.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OQS04490.1 - 1.3e-08 34.0 0.0 1.9e-08 33.5 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Pox_ser-thr_kin PF05445.11 OQS04490.1 - 0.0019 17.2 0.1 0.0034 16.4 0.1 1.3 1 0 0 1 1 1 1 Poxvirus serine/threonine protein kinase APH PF01636.23 OQS04490.1 - 0.018 15.0 0.0 0.032 14.1 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.14 OQS04490.1 - 0.092 12.1 0.1 0.15 11.4 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Cript PF10235.9 OQS04491.1 - 1.2e-26 93.0 7.3 1.2e-26 93.0 7.3 2.0 2 1 0 2 2 2 1 Microtubule-associated protein CRIPT Se-cys_synth_N PF12390.8 OQS04491.1 - 0.17 12.1 0.8 0.44 10.8 0.2 1.9 2 0 0 2 2 2 0 Selenocysteine synthase N terminal DZR PF12773.7 OQS04491.1 - 0.18 11.8 10.8 0.43 10.6 6.6 2.4 1 1 1 2 2 2 0 Double zinc ribbon zinc_ribbon_15 PF17032.5 OQS04491.1 - 0.44 11.3 10.7 0.31 11.8 6.9 2.5 2 1 0 2 2 2 0 zinc-ribbon family DUF2039 PF10217.9 OQS04491.1 - 0.82 10.1 14.7 7.8 6.9 14.7 2.5 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2039) DUF1272 PF06906.11 OQS04491.1 - 2.5 8.3 8.3 0.45 10.6 4.3 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1272) Gin PF10764.9 OQS04491.1 - 2.8 8.0 9.6 24 5.0 3.5 3.7 3 1 0 3 3 3 0 Inhibitor of sigma-G Gin zf-Di19 PF05605.12 OQS04491.1 - 5.4 7.4 9.2 3.6 7.9 0.8 2.9 2 1 1 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding ELMO_CED12 PF04727.13 OQS04492.1 - 1.4e-40 139.3 0.1 2.5e-40 138.5 0.1 1.4 1 0 0 1 1 1 1 ELMO/CED-12 family Ank_2 PF12796.7 OQS04493.1 - 9.5e-156 506.8 23.2 1.7e-18 66.9 0.1 12.8 2 2 8 12 12 12 12 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQS04493.1 - 7.3e-119 386.8 14.4 1.6e-10 41.3 0.0 18.2 7 6 11 18 18 18 18 Ankyrin repeats (many copies) Ank PF00023.30 OQS04493.1 - 2e-108 350.5 55.4 6.5e-07 29.5 0.1 25.0 24 1 1 25 25 25 23 Ankyrin repeat Ank_3 PF13606.6 OQS04493.1 - 1.1e-95 301.9 20.9 4e-05 23.7 0.0 24.6 25 0 0 25 25 25 20 Ankyrin repeat Ank_5 PF13857.6 OQS04493.1 - 1.4e-95 312.1 27.2 4.4e-10 39.6 0.0 17.7 7 5 12 19 19 19 17 Ankyrin repeats (many copies) YfmQ PF10787.9 OQS04493.1 - 1.1e-08 34.9 0.0 29 4.4 0.0 10.4 8 5 6 14 14 14 0 Uncharacterised protein from bacillus cereus group PEGA PF08308.11 OQS04493.1 - 1.8e-05 24.6 3.1 77 3.3 0.0 9.2 11 1 0 11 11 11 0 PEGA domain Mqo PF06039.15 OQS04493.1 - 0.00037 19.2 0.1 0.56 8.7 0.0 5.3 4 2 3 7 7 7 1 Malate:quinone oxidoreductase (Mqo) Imm_superinfect PF14373.6 OQS04493.1 - 0.0035 17.2 8.6 18 5.3 0.0 9.0 10 0 0 10 10 10 0 Superinfection immunity protein ATPase PF06745.13 OQS04493.1 - 0.02 14.2 0.0 1.3e+02 1.7 0.0 5.4 5 2 2 7 7 7 0 KaiC HEM4 PF02602.15 OQS04493.1 - 0.036 13.4 0.0 2.1e+02 1.1 0.0 5.6 5 2 1 7 7 7 0 Uroporphyrinogen-III synthase HemD GATase_7 PF13537.6 OQS04493.1 - 0.05 13.5 0.0 1.3e+02 2.5 0.0 6.0 8 0 0 8 8 8 0 Glutamine amidotransferase domain Arg_repressor PF01316.21 OQS04493.1 - 0.15 11.9 1.7 2.8e+02 1.4 0.0 6.0 8 0 0 8 8 8 0 Arginine repressor, DNA binding domain SARAF PF06682.12 OQS04494.1 - 1.2 8.8 5.3 0.24 11.0 0.1 2.2 2 1 0 2 2 2 0 SOCE-associated regulatory factor of calcium homoeostasis bZIP_1 PF00170.21 OQS04495.1 - 8.4e-08 32.2 13.0 1.7e-07 31.2 13.0 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 OQS04495.1 - 5.5e-06 26.4 18.3 5.5e-06 26.4 18.3 1.6 2 0 0 2 2 2 1 Basic region leucine zipper bZIP_Maf PF03131.17 OQS04495.1 - 0.0052 17.3 10.3 0.0052 17.3 10.3 1.6 2 0 0 2 2 2 1 bZIP Maf transcription factor Atg14 PF10186.9 OQS04495.1 - 0.036 13.1 3.8 0.052 12.6 3.8 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Cir_N PF10197.9 OQS04495.1 - 5.7 7.2 7.7 14 5.9 7.7 1.7 1 0 0 1 1 1 0 N-terminal domain of CBF1 interacting co-repressor CIR Synaptobrevin PF00957.21 OQS04496.1 - 2.4e-27 94.6 0.7 4e-27 93.8 0.7 1.4 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.6 OQS04496.1 - 2.7e-08 33.8 0.0 4.7e-08 33.0 0.0 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain Sigma_reg_N PF13800.6 OQS04496.1 - 0.0055 17.0 0.4 0.011 16.0 0.4 1.4 1 0 0 1 1 1 1 Sigma factor regulator N-terminal ODV-E18 PF10717.9 OQS04496.1 - 0.17 11.8 0.1 0.17 11.8 0.1 1.8 2 0 0 2 2 2 0 Occlusion-derived virus envelope protein ODV-E18 RIBIOP_C PF04950.12 OQS04497.1 - 1.8e-106 355.8 0.0 2.8e-106 355.2 0.0 1.3 1 0 0 1 1 1 1 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal AARP2CN PF08142.12 OQS04497.1 - 8.4e-14 51.4 0.1 2.3e-13 50.0 0.1 1.8 1 0 0 1 1 1 1 AARP2CN (NUC121) domain ubiquitin PF00240.23 OQS04498.1 - 1.2e-18 66.7 0.0 2.1e-18 65.8 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 OQS04498.1 - 4.9e-05 23.1 0.0 0.00014 21.7 0.0 1.8 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 OQS04498.1 - 0.0025 18.2 0.0 0.0055 17.1 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin-like domain PLAC8 PF04749.17 OQS04499.1 - 1.4e-17 64.5 28.9 1.9e-17 64.0 28.9 1.2 1 0 0 1 1 1 1 PLAC8 family TTL PF03133.15 OQS04500.1 - 7.5e-73 245.2 4.8 7.5e-73 245.2 4.8 2.3 2 1 0 2 2 2 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 OQS04500.1 - 1.3e-07 31.2 0.2 1.7e-05 24.2 0.0 2.9 2 1 1 3 3 3 1 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 OQS04500.1 - 0.00016 21.0 0.1 0.014 14.7 0.0 2.7 2 1 0 2 2 2 2 Sugar-transfer associated ATP-grasp LtrA PF06772.11 OQS04501.1 - 5.9e-28 98.1 37.0 7.8e-28 97.7 37.0 1.2 1 0 0 1 1 1 1 Bacterial low temperature requirement A protein (LtrA) Ank_5 PF13857.6 OQS04502.1 - 6e-06 26.4 0.1 3.8e-05 23.9 0.1 2.1 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQS04502.1 - 9.1e-06 25.7 0.1 0.13 12.9 0.1 2.6 2 0 0 2 2 2 2 Ankyrin repeat Ank PF00023.30 OQS04502.1 - 0.0018 18.6 0.4 1.8 9.1 0.0 2.7 3 0 0 3 3 3 2 Ankyrin repeat Ank_2 PF12796.7 OQS04502.1 - 0.053 14.1 0.0 0.095 13.3 0.0 1.4 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) DUF4208 PF13907.6 OQS04503.1 - 2.2e-11 44.1 0.1 5.5e-11 42.8 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4208) SLIDE PF09111.10 OQS04503.1 - 0.0004 20.4 1.4 0.0021 18.1 0.1 2.4 2 0 0 2 2 2 1 SLIDE U3snoRNP10 PF12397.8 OQS04503.1 - 0.00067 20.0 0.3 0.0049 17.2 0.0 2.2 2 0 0 2 2 2 1 U3 small nucleolar RNA-associated protein 10 CHDCT2 PF08074.11 OQS04503.1 - 0.043 14.0 0.0 0.18 12.0 0.0 2.1 1 0 0 1 1 1 0 CHDCT2 (NUC038) domain Macoilin PF09726.9 OQS04503.1 - 1.6 7.2 6.6 2.6 6.5 6.6 1.4 1 0 0 1 1 1 0 Macoilin family DUF4598 PF15370.6 OQS04503.1 - 2.3 8.7 5.4 8.3 6.9 5.4 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4598) IMUP PF15761.5 OQS04503.1 - 2.5 8.8 15.5 11 6.8 15.5 2.1 1 0 0 1 1 1 0 Immortalisation up-regulated protein DUF3618 PF12277.8 OQS04503.1 - 2.9 8.2 4.5 6.9 7.0 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3618) CCDC106 PF15794.5 OQS04503.1 - 3.7 7.2 10.0 0.27 10.9 4.6 1.8 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 106 DEAD PF00270.29 OQS04504.1 - 6.7e-39 133.5 0.1 1.6e-38 132.3 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OQS04504.1 - 6e-24 84.5 0.2 1.4e-21 76.9 0.1 2.4 2 0 0 2 2 2 2 Helicase conserved C-terminal domain ResIII PF04851.15 OQS04504.1 - 6e-10 39.4 0.0 1.6e-09 38.0 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Flavi_DEAD PF07652.14 OQS04504.1 - 0.018 15.0 0.2 0.054 13.5 0.2 1.9 1 1 0 1 1 1 0 Flavivirus DEAD domain AAA_22 PF13401.6 OQS04504.1 - 0.024 14.9 1.7 0.5 10.6 0.5 3.1 2 1 0 2 2 2 0 AAA domain DUF2431 PF10354.9 OQS04505.1 - 8.4e-35 120.5 0.0 1.2e-34 120.0 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF2431) FDX-ACB PF03147.14 OQS04505.1 - 1.1e-05 25.8 0.0 2.2e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 Ferredoxin-fold anticodon binding domain MTS PF05175.14 OQS04505.1 - 0.0063 16.1 0.0 0.0099 15.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_4 PF02390.17 OQS04505.1 - 0.038 13.5 0.1 0.081 12.4 0.1 1.5 1 0 0 1 1 1 0 Putative methyltransferase IDO PF01231.18 OQS04505.1 - 0.12 11.1 0.1 0.18 10.5 0.1 1.3 1 0 0 1 1 1 0 Indoleamine 2,3-dioxygenase MFS_5 PF05631.14 OQS04506.1 - 3.1e-68 230.3 11.2 4.1e-68 229.9 11.2 1.1 1 0 0 1 1 1 1 Sugar-tranasporters, 12 TM MFS_1 PF07690.16 OQS04506.1 - 8.7e-16 57.8 28.5 8.7e-16 57.8 28.5 2.1 2 1 1 3 3 3 2 Major Facilitator Superfamily PRIMA1 PF16101.5 OQS04507.1 - 0.064 13.3 3.0 0.041 13.9 1.0 1.7 1 1 1 2 2 2 0 Proline-rich membrane anchor 1 TMEM154 PF15102.6 OQS04507.1 - 0.21 11.5 1.1 0.3 11.0 1.1 1.2 1 0 0 1 1 1 0 TMEM154 protein family FXMRP1_C_core PF12235.8 OQS04508.1 - 0.54 10.9 5.9 0.58 10.8 4.8 1.7 1 1 0 1 1 1 0 Fragile X-related 1 protein core C terminal Acyl_transf_3 PF01757.22 OQS04509.1 - 9.3e-21 74.2 31.7 9.3e-21 74.2 31.7 3.5 2 1 1 3 3 3 1 Acyltransferase family BT1 PF03092.16 OQS04509.1 - 5.4e-07 28.2 1.8 5.4e-07 28.2 1.8 2.6 3 0 0 3 3 3 1 BT1 family DoxX_2 PF13564.6 OQS04509.1 - 9.6 6.4 9.0 0.16 12.1 0.2 2.6 3 0 0 3 3 3 0 DoxX-like family Kinesin PF00225.23 OQS04510.1 - 4.5e-109 364.4 1.2 2.5e-108 361.9 0.1 2.7 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 OQS04510.1 - 8.5e-22 77.7 2.2 1.4e-21 77.0 0.0 2.6 3 0 0 3 3 3 1 Microtubule binding UvrC_HhH_N PF08459.11 OQS04510.1 - 0.067 13.1 3.3 0.31 10.9 3.3 2.2 1 0 0 1 1 1 0 UvrC Helix-hairpin-helix N-terminal NADH_oxidored PF08040.11 OQS04510.1 - 0.8 9.4 3.7 0.36 10.6 0.7 1.9 2 0 0 2 2 2 0 MNLL subunit DUF4065 PF13274.6 OQS04510.1 - 2.3 9.1 6.2 13 6.7 0.2 3.7 3 1 0 3 3 3 0 Protein of unknown function (DUF4065) HRDC PF00570.23 OQS04510.1 - 9.3 6.3 7.2 67 3.6 0.1 3.8 4 0 0 4 4 4 0 HRDC domain WD40 PF00400.32 OQS04512.1 - 0.00015 22.5 0.0 0.06 14.2 0.0 3.4 3 0 0 3 3 3 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OQS04512.1 - 0.00028 21.1 0.1 0.43 10.9 0.0 3.8 1 1 2 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain BBS2_N PF14781.6 OQS04512.1 - 0.018 14.9 0.2 0.21 11.5 0.2 2.5 1 1 0 1 1 1 0 Ciliary BBSome complex subunit 2, N-terminal WW PF00397.26 OQS04513.1 - 5e-10 39.3 2.7 1.1e-09 38.2 2.7 1.7 1 0 0 1 1 1 1 WW domain APG6_N PF17675.1 OQS04513.1 - 0.00024 21.6 3.7 0.00024 21.6 3.7 6.6 3 1 4 7 7 7 2 Apg6 coiled-coil region FlxA PF14282.6 OQS04513.1 - 0.0046 16.9 8.0 0.0046 16.9 8.0 8.3 4 3 3 8 8 8 1 FlxA-like protein Filament PF00038.21 OQS04513.1 - 0.83 9.2 83.5 0.28 10.7 9.2 6.1 1 1 4 5 5 5 0 Intermediate filament protein DUF724 PF05266.14 OQS04513.1 - 6 6.7 77.1 0.088 12.6 3.7 6.7 2 2 4 6 6 6 0 Protein of unknown function (DUF724) EF-hand_1 PF00036.32 OQS04514.1 - 6.6e-10 37.8 1.3 0.00083 18.7 0.1 2.7 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 OQS04514.1 - 1.4e-08 35.0 1.0 0.0022 18.4 0.4 2.6 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 OQS04514.1 - 5e-08 32.3 1.6 0.0099 15.7 0.1 2.8 3 0 0 3 3 3 2 EF-hand domain EF-hand_5 PF13202.6 OQS04514.1 - 3.8e-05 23.0 2.8 0.005 16.3 0.1 2.9 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.6 OQS04514.1 - 4.5e-05 23.2 3.8 0.12 12.2 0.1 3.6 3 0 0 3 3 3 2 EF-hand domain pair DNA_III_psi PF03603.13 OQS04514.1 - 0.019 15.2 0.0 0.04 14.2 0.0 1.6 1 0 0 1 1 1 0 DNA polymerase III psi subunit LIG3_BRCT PF16759.5 OQS04514.1 - 0.075 13.3 0.0 0.16 12.3 0.0 1.5 1 0 0 1 1 1 0 DNA ligase 3 BRCT domain MINDY_DUB PF04424.13 OQS04515.1 - 0.11 12.5 0.0 0.13 12.3 0.0 1.2 1 0 0 1 1 1 0 MINDY deubiquitinase Nitroreductase PF00881.24 OQS04516.1 - 2.4e-25 89.6 0.0 2.9e-25 89.3 0.0 1.1 1 0 0 1 1 1 1 Nitroreductase family Amidase_3 PF01520.18 OQS04516.1 - 0.035 14.2 0.0 0.05 13.7 0.0 1.2 1 0 0 1 1 1 0 N-acetylmuramoyl-L-alanine amidase FAD_binding_2 PF00890.24 OQS04518.1 - 2e-121 406.0 5.0 2.8e-121 405.5 5.0 1.2 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.20 OQS04518.1 - 1.5e-45 154.3 1.4 2.8e-45 153.4 1.4 1.4 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term Thi4 PF01946.17 OQS04518.1 - 7.9e-05 22.0 0.8 0.029 13.6 0.2 2.4 2 0 0 2 2 2 2 Thi4 family Pyr_redox_2 PF07992.14 OQS04518.1 - 0.00044 19.6 0.8 0.0014 17.9 0.3 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 OQS04518.1 - 0.011 14.8 8.4 0.03 13.4 4.2 2.7 3 0 0 3 3 3 0 Glucose inhibited division protein A HI0933_like PF03486.14 OQS04518.1 - 0.013 14.2 0.5 0.039 12.7 0.4 1.9 2 0 0 2 2 2 0 HI0933-like protein FAD_binding_3 PF01494.19 OQS04518.1 - 0.021 14.1 0.3 0.045 13.0 0.3 1.5 1 0 0 1 1 1 0 FAD binding domain DAO PF01266.24 OQS04518.1 - 0.032 13.8 1.5 0.065 12.8 0.4 2.0 3 0 0 3 3 3 0 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 OQS04518.1 - 0.12 11.4 0.7 0.17 10.9 0.1 1.6 2 0 0 2 2 2 0 Lycopene cyclase protein FAD_oxidored PF12831.7 OQS04518.1 - 1.1 8.5 4.6 3.3 7.0 4.6 1.8 1 0 0 1 1 1 0 FAD dependent oxidoreductase GMC_oxred_N PF00732.19 OQS04519.1 - 9.7e-27 94.1 0.0 2e-20 73.3 0.0 2.4 2 1 0 2 2 2 2 GMC oxidoreductase GMC_oxred_C PF05199.13 OQS04519.1 - 5.2e-10 40.0 0.4 1.1e-09 38.9 0.1 1.6 2 0 0 2 2 2 1 GMC oxidoreductase FAD_binding_2 PF00890.24 OQS04519.1 - 5e-09 35.7 0.0 0.0009 18.4 0.1 2.2 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.24 OQS04519.1 - 2.9e-07 30.4 0.2 7.4e-05 22.5 0.3 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 OQS04519.1 - 3.9e-06 27.0 0.0 1.2e-05 25.4 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 OQS04519.1 - 1.1e-05 24.9 0.0 0.00038 19.8 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 OQS04519.1 - 0.00018 20.9 0.1 0.00049 19.4 0.1 1.7 2 0 0 2 2 2 1 Thi4 family FAD_binding_3 PF01494.19 OQS04519.1 - 0.0005 19.4 0.3 0.00085 18.7 0.3 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.6 OQS04519.1 - 0.0011 18.3 0.2 0.16 11.2 0.1 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 OQS04519.1 - 0.0011 18.1 0.1 0.0022 17.1 0.1 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein HI0933_like PF03486.14 OQS04519.1 - 0.0019 17.0 0.2 0.0055 15.5 0.1 1.7 2 0 0 2 2 2 1 HI0933-like protein GIDA PF01134.22 OQS04519.1 - 0.031 13.4 0.1 5.1 6.1 0.0 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A PPDK_N PF01326.19 OQS04519.1 - 0.055 12.7 0.1 0.17 11.1 0.1 1.7 2 0 0 2 2 2 0 Pyruvate phosphate dikinase, PEP/pyruvate binding domain WW PF00397.26 OQS04520.1 - 2.8e-10 40.1 1.7 7.3e-10 38.8 1.7 1.8 1 0 0 1 1 1 1 WW domain DUF948 PF06103.11 OQS04520.1 - 0.2 12.0 0.5 16 5.9 0.2 2.5 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Zein-binding PF04576.15 OQS04520.1 - 0.22 11.8 2.0 0.36 11.1 0.4 2.1 2 0 0 2 2 2 0 Zein-binding Matrilin_ccoil PF10393.9 OQS04520.1 - 0.64 9.9 4.2 3.7 7.5 0.2 2.5 2 1 0 2 2 2 0 Trimeric coiled-coil oligomerisation domain of matrilin P34-Arc PF04045.14 OQS04521.1 - 2.4e-76 256.6 0.0 2.9e-76 256.4 0.0 1.0 1 0 0 1 1 1 1 Arp2/3 complex, 34 kD subunit p34-Arc tRNA_bind PF01588.20 OQS04522.1 - 1.3e-21 76.5 3.6 4.6e-21 74.7 3.6 1.7 1 1 0 1 1 1 1 Putative tRNA binding domain GlcNAc PF11397.8 OQS04523.1 - 5.1e-44 151.2 0.0 2.6e-36 125.8 0.0 2.2 1 1 1 2 2 2 2 Glycosyltransferase (GlcNAc) Glycos_transf_2 PF00535.26 OQS04523.1 - 0.00015 21.7 0.0 0.0046 16.8 0.0 2.4 2 0 0 2 2 2 1 Glycosyl transferase family 2 NAGLU PF05089.12 OQS04524.1 - 5.2e-137 456.3 3.7 7.3e-137 455.8 3.7 1.2 1 0 0 1 1 1 1 Alpha-N-acetylglucosaminidase (NAGLU) tim-barrel domain NAGLU_C PF12972.7 OQS04524.1 - 3.1e-78 263.0 3.0 5e-78 262.3 3.0 1.3 1 0 0 1 1 1 1 Alpha-N-acetylglucosaminidase (NAGLU) C-terminal domain NAGLU_N PF12971.7 OQS04524.1 - 3e-15 55.8 0.2 1.2e-14 53.8 0.0 2.2 2 0 0 2 2 2 1 Alpha-N-acetylglucosaminidase (NAGLU) N-terminal domain Orthoreo_P10 PF07204.11 OQS04525.1 - 0.0016 18.4 0.4 0.0043 17.0 0.0 1.9 2 0 0 2 2 2 1 Orthoreovirus membrane fusion protein p10 DUF1179 PF06678.11 OQS04525.1 - 0.0058 16.6 0.8 0.0058 16.6 0.8 2.9 2 1 0 2 2 2 1 Protein of unknown function (DUF1179) FAM163 PF15069.6 OQS04525.1 - 0.0087 16.5 0.5 0.0087 16.5 0.5 2.4 2 1 1 3 3 3 1 FAM163 family EphA2_TM PF14575.6 OQS04525.1 - 0.018 15.9 0.0 0.071 14.0 0.0 2.0 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain WBP-1 PF11669.8 OQS04525.1 - 0.045 14.4 0.1 0.045 14.4 0.1 2.3 3 0 0 3 3 3 0 WW domain-binding protein 1 DAP10 PF07213.11 OQS04525.1 - 0.12 12.3 0.1 0.12 12.3 0.1 2.2 3 0 0 3 3 3 0 DAP10 membrane protein TMIE PF16038.5 OQS04525.1 - 0.23 11.3 1.6 0.4 10.6 0.8 1.7 2 0 0 2 2 2 0 TMIE protein Serglycin PF04360.12 OQS04525.1 - 0.43 10.5 8.4 0.034 14.1 1.2 2.4 2 0 0 2 2 2 0 Serglycin DUF2561 PF10812.8 OQS04525.1 - 0.68 9.9 0.0 0.68 9.9 0.0 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF2561) Cadherin_C_2 PF16492.5 OQS04525.1 - 0.84 10.4 0.0 0.84 10.4 0.0 2.7 2 1 0 2 2 2 0 Cadherin cytoplasmic C-terminal WD40 PF00400.32 OQS04526.1 - 7.5e-17 61.4 13.7 4.5e-05 24.1 0.1 9.0 8 0 0 8 8 8 3 WD domain, G-beta repeat EF-hand_6 PF13405.6 OQS04526.1 - 3.6e-13 48.3 8.3 0.011 15.7 0.0 5.8 5 0 0 5 5 5 4 EF-hand domain EF-hand_7 PF13499.6 OQS04526.1 - 2.9e-12 46.9 5.7 1.9e-05 25.0 0.3 4.7 3 1 1 4 4 4 3 EF-hand domain pair EF-hand_1 PF00036.32 OQS04526.1 - 9e-11 40.5 15.0 0.0087 15.5 0.3 5.3 6 0 0 6 6 6 4 EF hand EF-hand_5 PF13202.6 OQS04526.1 - 3.9e-08 32.4 2.4 0.36 10.4 0.1 4.3 4 0 0 4 4 4 3 EF hand ANAPC4_WD40 PF12894.7 OQS04526.1 - 0.011 16.0 0.0 7.3 7.0 0.0 4.6 3 1 1 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain EF-hand_8 PF13833.6 OQS04526.1 - 0.039 13.8 5.2 22 5.0 0.2 3.9 4 0 0 4 4 4 0 EF-hand domain pair EF-hand_1 PF00036.32 OQS04527.1 - 0.00019 20.7 0.7 0.0006 19.2 0.7 1.9 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 OQS04527.1 - 0.002 17.9 0.6 0.002 17.9 0.6 2.2 2 0 0 2 2 2 1 EF-hand domain EF-hand_8 PF13833.6 OQS04527.1 - 0.0044 16.8 0.5 0.026 14.4 0.4 2.5 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_5 PF13202.6 OQS04527.1 - 0.0046 16.4 0.4 0.012 15.0 0.4 1.7 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.6 OQS04527.1 - 0.02 15.3 0.4 0.02 15.3 0.4 3.5 4 0 0 4 4 4 0 EF-hand domain pair Myb_DNA-binding PF00249.31 OQS04528.1 - 2e-08 34.3 0.1 3.3e-08 33.6 0.1 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OQS04528.1 - 0.014 15.6 0.1 0.025 14.8 0.1 1.5 1 0 0 1 1 1 0 Myb-like DNA-binding domain MRC1 PF09444.10 OQS04528.1 - 0.078 13.5 2.0 0.13 12.8 2.0 1.3 1 0 0 1 1 1 0 MRC1-like domain PALP PF00291.25 OQS04529.1 - 1.7e-66 224.6 0.0 2.2e-66 224.2 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Sensor PF13796.6 OQS04529.1 - 1.6e-10 41.3 14.1 1e-06 28.9 4.1 3.0 2 1 0 2 2 2 2 Putative sensor RabGAP-TBC PF00566.18 OQS04530.1 - 5.9e-19 68.6 0.0 1.3e-18 67.4 0.0 1.5 1 1 0 1 1 1 1 Rab-GTPase-TBC domain PH PF00169.29 OQS04530.1 - 3.2e-17 63.0 0.0 1.7e-09 38.1 0.0 2.4 2 0 0 2 2 2 2 PH domain PH_9 PF15410.6 OQS04530.1 - 0.0024 18.2 0.1 1.4 9.3 0.1 2.4 2 0 0 2 2 2 2 Pleckstrin homology domain PDZ_6 PF17820.1 OQS04530.1 - 0.11 12.3 0.0 0.42 10.5 0.0 1.9 2 0 0 2 2 2 0 PDZ domain PH_11 PF15413.6 OQS04530.1 - 0.13 12.7 0.0 1.8 9.0 0.1 2.4 2 0 0 2 2 2 0 Pleckstrin homology domain Ank_2 PF12796.7 OQS04531.1 - 2.9e-96 316.2 35.9 1.6e-20 73.5 1.4 6.6 2 1 6 8 8 8 7 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OQS04531.1 - 5.3e-52 167.7 12.3 7.9e-05 22.8 0.1 12.2 12 0 0 12 12 12 11 Ankyrin repeat Ank_4 PF13637.6 OQS04531.1 - 3.3e-50 167.8 13.1 1.2e-11 44.8 0.2 9.4 2 1 7 10 10 10 9 Ankyrin repeats (many copies) Ank PF00023.30 OQS04531.1 - 7.1e-49 162.2 20.5 1.7e-06 28.2 0.2 11.1 11 0 0 11 11 11 9 Ankyrin repeat Ank_5 PF13857.6 OQS04531.1 - 5.2e-38 128.6 20.5 2.9e-07 30.6 0.2 9.0 3 1 7 10 10 10 9 Ankyrin repeats (many copies) His_Phos_2 PF00328.22 OQS04531.1 - 2.2e-28 99.7 1.1 3.6e-28 99.0 1.1 1.3 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) CEP44 PF15007.6 OQS04532.1 - 4.6e-31 107.6 0.6 8e-31 106.8 0.6 1.4 1 0 0 1 1 1 1 Centrosomal spindle body, CEP44 IRK_C PF17655.1 OQS04533.1 - 2.2e-28 99.0 0.3 2.7e-14 53.2 0.0 2.6 3 0 0 3 3 3 2 Inward rectifier potassium channel C-terminal domain IRK PF01007.20 OQS04533.1 - 3.5e-12 46.3 8.2 2.1e-11 43.8 8.2 2.0 1 1 0 1 1 1 1 Inward rectifier potassium channel transmembrane domain Ion_trans_2 PF07885.16 OQS04533.1 - 0.004 17.1 7.0 0.0098 15.8 7.0 1.7 1 1 0 1 1 1 1 Ion channel PsbT PF01405.17 OQS04533.1 - 8.2 6.3 10.5 3.3 7.6 4.0 2.6 2 0 0 2 2 2 0 Photosystem II reaction centre T protein DDE_1 PF03184.19 OQS04534.1 - 2.4e-07 30.6 0.0 4.4e-07 29.7 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease IQ PF00612.27 OQS04536.1 - 4.4e-32 106.8 91.8 0.00023 20.7 0.2 17.7 16 1 1 17 17 17 13 IQ calmodulin-binding motif EF-hand_1 PF00036.32 OQS04536.1 - 2.9e-14 51.4 1.2 3.6e-06 26.1 0.9 2.7 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 OQS04536.1 - 7.2e-12 45.6 2.2 2.2e-11 44.0 0.8 2.7 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_5 PF13202.6 OQS04536.1 - 3.6e-11 42.0 1.6 2.3e-05 23.6 0.0 2.9 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 OQS04536.1 - 1.5e-10 40.7 0.6 3.5e-10 39.6 0.6 1.7 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 OQS04536.1 - 8.8e-10 37.7 0.3 0.00013 21.6 0.0 3.0 2 0 0 2 2 2 2 EF-hand domain WW PF00397.26 OQS04536.1 - 8.9e-09 35.3 26.0 2.5e-06 27.4 2.3 3.5 3 0 0 3 3 3 2 WW domain EF-hand_9 PF14658.6 OQS04536.1 - 2.5e-05 24.5 0.0 7.1e-05 23.1 0.0 1.8 1 0 0 1 1 1 1 EF-hand domain EF-hand_4 PF12763.7 OQS04536.1 - 0.0016 18.3 0.1 0.0085 16.0 0.1 2.3 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand Acetyltransf_1 PF00583.25 OQS04537.1 - 1e-13 51.5 0.0 1.3e-13 51.2 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 OQS04537.1 - 2.1e-08 34.2 0.0 2.7e-08 33.8 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 OQS04537.1 - 8.6e-08 32.5 0.1 1.4e-07 31.9 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 OQS04537.1 - 0.00047 20.1 0.1 0.00074 19.4 0.1 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_4 PF13420.7 OQS04537.1 - 0.0013 18.9 0.2 0.0018 18.4 0.2 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 OQS04537.1 - 0.0014 19.3 0.0 0.0018 18.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain ROK PF00480.20 OQS04537.1 - 0.045 13.2 0.0 0.064 12.7 0.0 1.1 1 0 0 1 1 1 0 ROK family Acetyltransf_9 PF13527.7 OQS04537.1 - 0.052 13.6 0.1 0.068 13.3 0.1 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Glyoxalase_3 PF13468.6 OQS04537.1 - 0.12 12.5 0.1 0.23 11.6 0.1 1.4 1 0 0 1 1 1 0 Glyoxalase-like domain Acetyltransf_8 PF13523.6 OQS04537.1 - 0.16 11.6 0.0 0.21 11.3 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Met_10 PF02475.16 OQS04538.1 - 4.8e-65 219.0 0.0 7.6e-65 218.4 0.0 1.3 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_25 PF13649.6 OQS04538.1 - 0.00049 20.8 0.0 0.0012 19.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain tRNA_U5-meth_tr PF05958.11 OQS04538.1 - 0.00061 18.9 0.1 0.001 18.1 0.1 1.4 1 0 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase MTS PF05175.14 OQS04538.1 - 0.00082 19.0 0.0 0.0014 18.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_15 PF09445.10 OQS04538.1 - 0.0011 18.5 0.0 0.0031 17.1 0.0 1.7 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_11 PF08241.12 OQS04538.1 - 0.0064 17.1 0.0 0.014 16.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OQS04538.1 - 0.028 14.3 0.0 0.047 13.5 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain TehB PF03848.14 OQS04538.1 - 0.045 13.2 0.2 0.18 11.2 0.0 2.0 2 1 0 2 2 2 0 Tellurite resistance protein TehB TRM PF02005.16 OQS04538.1 - 0.063 12.4 0.0 0.094 11.9 0.0 1.2 1 0 0 1 1 1 0 N2,N2-dimethylguanosine tRNA methyltransferase PrmA PF06325.13 OQS04538.1 - 0.14 11.5 0.0 0.23 10.8 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Metallophos PF00149.28 OQS04539.1 - 5.7e-16 59.6 1.0 9.3e-16 58.9 1.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Pur_ac_phosph_N PF16656.5 OQS04539.1 - 4.3e-15 56.1 1.3 8.4e-15 55.1 0.0 2.1 2 1 0 2 2 2 1 Purple acid Phosphatase, N-terminal domain Metallophos_C PF14008.6 OQS04539.1 - 4.8e-12 46.6 0.5 1.2e-11 45.3 0.5 1.7 1 0 0 1 1 1 1 Iron/zinc purple acid phosphatase-like protein C PhoD PF09423.10 OQS04539.1 - 0.015 14.4 0.1 1.3 8.0 0.0 2.2 2 0 0 2 2 2 0 PhoD-like phosphatase Arf PF00025.21 OQS04540.1 - 1.3e-42 145.2 0.0 5e-42 143.3 0.0 1.7 1 1 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 OQS04540.1 - 1.4e-12 47.9 0.0 2.1e-12 47.3 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 OQS04540.1 - 4.7e-12 45.8 0.0 7.6e-12 45.1 0.0 1.3 1 1 0 1 1 1 1 Ras family SRPRB PF09439.10 OQS04540.1 - 3e-10 39.8 0.0 5.1e-10 39.1 0.0 1.4 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 OQS04540.1 - 1.9e-05 24.0 0.2 0.17 11.0 0.0 2.4 1 1 1 2 2 2 2 G-protein alpha subunit MMR_HSR1 PF01926.23 OQS04540.1 - 0.00066 19.7 0.0 0.0013 18.8 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 OQS04540.1 - 0.0082 16.5 0.0 1.6 9.1 0.0 2.1 1 1 0 2 2 2 1 AAA ATPase domain GTP_EFTU PF00009.27 OQS04540.1 - 0.037 13.6 0.1 0.23 11.0 0.1 2.0 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain AAA_18 PF13238.6 OQS04540.1 - 0.088 13.4 0.0 0.15 12.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain bZIP_2 PF07716.15 OQS04541.1 - 0.00085 19.4 5.9 0.0015 18.6 5.9 1.4 1 0 0 1 1 1 1 Basic region leucine zipper DASH_Dad4 PF08650.10 OQS04541.1 - 0.042 13.8 0.1 0.15 12.0 0.1 1.9 1 0 0 1 1 1 0 DASH complex subunit Dad4 bZIP_1 PF00170.21 OQS04541.1 - 0.53 10.4 7.8 1.1 9.4 7.8 1.5 1 0 0 1 1 1 0 bZIP transcription factor Kinesin PF00225.23 OQS04542.1 - 5.4e-89 298.4 0.9 1e-88 297.5 0.9 1.5 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 OQS04542.1 - 2.4e-24 86.0 1.2 1.4e-22 80.2 0.0 2.9 2 0 0 2 2 2 1 Microtubule binding Ribosomal_S5_C PF03719.15 OQS04542.1 - 1.1e-18 66.4 0.0 2.5e-18 65.3 0.0 1.6 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain Ribosomal_S5 PF00333.20 OQS04542.1 - 1e-13 51.1 0.3 2.3e-13 49.9 0.3 1.7 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain CHASE3 PF05227.13 OQS04542.1 - 0.0076 16.2 3.5 0.11 12.4 0.0 2.8 2 0 0 2 2 2 1 CHASE3 domain Corona_nucleoca PF00937.18 OQS04542.1 - 0.02 14.0 0.0 0.046 12.7 0.0 1.5 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein RILP PF11461.8 OQS04542.1 - 0.021 15.0 2.5 0.092 13.0 2.5 2.2 1 0 0 1 1 1 0 Rab interacting lysosomal protein HR1 PF02185.16 OQS04544.1 - 0.04 14.0 1.5 0.04 14.0 1.5 2.2 2 0 0 2 2 2 0 Hr1 repeat Geminin PF07412.12 OQS04544.1 - 0.048 13.4 4.6 0.11 12.3 4.6 1.5 1 0 0 1 1 1 0 Geminin KRAB PF01352.27 OQS04544.1 - 0.063 12.9 0.6 1.5 8.5 0.2 2.5 2 0 0 2 2 2 0 KRAB box Ax_dynein_light PF10211.9 OQS04544.1 - 0.3 11.0 8.3 0.24 11.3 3.6 2.3 2 0 0 2 2 2 0 Axonemal dynein light chain UPF0203 PF05254.12 OQS04545.1 - 6.7e-10 39.1 5.7 6.9e-10 39.0 5.7 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0203) Fusion_F0 PF13044.6 OQS04545.1 - 0.13 10.9 0.0 0.13 10.8 0.0 1.0 1 0 0 1 1 1 0 Fusion glycoprotein F0, Isavirus CX9C PF16860.5 OQS04545.1 - 0.17 11.9 5.5 0.13 12.3 1.3 2.0 2 0 0 2 2 2 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, 2OG-FeII_Oxy_3 PF13640.6 OQS04546.1 - 1.2e-07 32.5 0.0 0.0046 17.8 0.0 2.7 2 0 0 2 2 2 2 2OG-Fe(II) oxygenase superfamily DUF4201 PF13870.6 OQS04547.1 - 5.4e-38 130.5 23.0 5.4e-38 130.5 23.0 2.6 2 1 0 2 2 2 1 Domain of unknown function (DUF4201) TraC_F_IV PF11130.8 OQS04547.1 - 0.049 13.2 4.0 0.036 13.7 1.1 2.1 2 0 0 2 2 2 0 F pilus assembly Type-IV secretion system for plasmid transfer DUF5101 PF17031.5 OQS04548.1 - 0.028 14.5 0.9 0.061 13.4 0.9 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5101) CCDC92 PF14916.6 OQS04548.1 - 0.035 13.9 0.2 0.11 12.3 0.2 1.8 1 0 0 1 1 1 0 Coiled-coil domain of unknown function DUF2408 PF10303.9 OQS04548.1 - 0.046 14.3 3.2 0.045 14.3 2.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2408) TSC22 PF01166.18 OQS04548.1 - 0.11 12.8 2.2 0.92 9.9 0.2 2.7 2 0 0 2 2 2 0 TSC-22/dip/bun family SWI-SNF_Ssr4 PF08549.10 OQS04548.1 - 0.11 11.1 2.6 0.16 10.6 2.6 1.1 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) PSD4 PF07631.11 OQS04548.1 - 0.17 12.5 1.6 0.38 11.3 1.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1592) HisKA PF00512.25 OQS04548.1 - 4.7 7.3 5.1 2.1 8.5 0.4 2.5 3 0 0 3 3 3 0 His Kinase A (phospho-acceptor) domain Nbas_N PF15492.6 OQS04550.1 - 0.18 11.1 0.0 0.39 10.0 0.0 1.4 1 0 0 1 1 1 0 Neuroblastoma-amplified sequence, N terminal DNA_pol_B_2 PF03175.13 OQS04551.1 - 5.3e-29 101.4 5.5 7.9e-29 100.8 4.3 1.9 1 1 1 2 2 2 1 DNA polymerase type B, organellar and viral S-methyl_trans PF02574.16 OQS04553.1 - 4.4e-53 180.8 0.0 5e-53 180.6 0.0 1.0 1 0 0 1 1 1 1 Homocysteine S-methyltransferase DUF3258 PF11646.8 OQS04555.1 - 0.0051 16.9 0.2 0.0095 16.0 0.2 1.5 1 0 0 1 1 1 1 Protein of unknown function DUF3258 Keratin PF02422.16 OQS04556.1 - 0.0019 17.9 1.1 0.0033 17.1 1.1 1.3 1 0 0 1 1 1 1 Keratin Polysacc_synt_4 PF04669.13 OQS04556.1 - 0.11 12.1 0.1 0.18 11.3 0.1 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis LZ_Tnp_IS66 PF13007.7 OQS04556.1 - 0.17 12.7 4.7 0.32 11.8 4.7 1.5 1 0 0 1 1 1 0 Transposase C of IS166 homeodomain Ricin_B_lectin PF00652.22 OQS04557.1 - 1.4e-30 106.1 20.8 9.7e-16 58.2 0.6 3.2 1 1 2 3 3 3 3 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.6 OQS04557.1 - 1.7e-12 47.9 7.7 9e-05 23.1 0.1 4.1 2 2 2 4 4 4 4 Ricin-type beta-trefoil lectin domain-like EABR PF12180.8 OQS04557.1 - 0.52 10.0 5.2 4.1 7.1 0.8 2.8 2 0 0 2 2 2 0 TSG101 and ALIX binding domain of CEP55 PT PF04886.12 OQS04557.1 - 0.84 9.2 5.3 1.8 8.2 5.3 1.5 1 0 0 1 1 1 0 PT repeat Elicitin PF00964.17 OQS04558.1 - 7.6e-08 32.3 0.2 8.6e-08 32.2 0.2 1.2 1 0 0 1 1 1 1 Elicitin zf_CopZ PF18423.1 OQS04558.1 - 0.036 14.0 0.0 0.071 13.1 0.0 1.6 1 0 0 1 1 1 0 Zinc binding domain zf-CGNR PF11706.8 OQS04558.1 - 0.077 12.9 0.0 0.15 12.0 0.0 1.5 1 0 0 1 1 1 0 CGNR zinc finger Inhibitor_I67 PF11405.8 OQS04558.1 - 0.099 12.9 3.3 0.12 12.7 2.4 1.6 1 1 1 2 2 2 0 Bromelain inhibitor VI zf-tcix PF14952.6 OQS04558.1 - 0.1 12.2 0.1 0.21 11.2 0.1 1.5 1 0 0 1 1 1 0 Putative treble-clef, zinc-finger, Zn-binding Aconitase PF00330.20 OQS04561.1 - 8.7e-65 219.5 0.7 8.4e-63 213.0 0.7 2.1 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 OQS04561.1 - 8.6e-18 64.9 0.0 2e-17 63.7 0.0 1.6 1 0 0 1 1 1 1 Aconitase C-terminal domain Histidinol_dh PF00815.20 OQS04562.1 - 0.047 12.7 0.0 0.065 12.2 0.0 1.1 1 0 0 1 1 1 0 Histidinol dehydrogenase AAA_16 PF13191.6 OQS04562.1 - 0.061 13.7 0.0 2.2 8.6 0.0 2.2 1 1 0 2 2 2 0 AAA ATPase domain MutS_V PF00488.21 OQS04563.1 - 8.3e-22 78.1 1.6 1.4e-20 74.2 1.6 2.6 1 1 0 1 1 1 1 MutS domain V MutS_III PF05192.18 OQS04563.1 - 0.0064 16.7 0.1 0.29 11.3 0.1 2.2 2 1 0 2 2 2 1 MutS domain III COP23 PF14218.6 OQS04563.1 - 0.12 12.2 0.2 0.51 10.1 0.0 2.0 2 0 0 2 2 2 0 Circadian oscillating protein COP23 AAA_29 PF13555.6 OQS04563.1 - 0.15 11.8 0.0 0.32 10.8 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain MutS_III PF05192.18 OQS04565.1 - 2.4e-22 80.1 1.3 3.1e-22 79.7 0.6 1.5 2 0 0 2 2 2 1 MutS domain III MutS_IV PF05190.18 OQS04565.1 - 0.0061 16.9 0.0 0.031 14.6 0.0 2.2 2 0 0 2 2 2 1 MutS family domain IV DUF3320 PF11784.8 OQS04565.1 - 0.036 14.0 0.3 0.075 13.0 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3320) Sec3-PIP2_bind PF15277.6 OQS04565.1 - 0.075 13.2 0.1 0.2 11.8 0.1 1.7 1 0 0 1 1 1 0 Exocyst complex component SEC3 N-terminal PIP2 binding PH Mss4 PF04421.13 OQS04565.1 - 0.086 13.0 0.1 0.27 11.4 0.1 1.8 1 0 0 1 1 1 0 Mss4 protein PH_BEACH PF14844.6 OQS04565.1 - 0.12 12.5 0.5 0.46 10.6 0.1 2.1 2 0 0 2 2 2 0 PH domain associated with Beige/BEACH TPR_12 PF13424.6 OQS04566.1 - 7.1e-06 26.2 0.1 0.00036 20.8 0.1 2.6 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_10 PF13374.6 OQS04566.1 - 0.00081 19.2 0.4 0.0044 16.8 0.0 2.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.6 OQS04566.1 - 0.0037 17.2 0.1 0.09 12.8 0.0 2.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 OQS04566.1 - 0.0072 16.4 0.1 2.4 8.5 0.0 2.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 OQS04566.1 - 0.0077 16.0 0.2 0.39 10.6 0.0 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 OQS04566.1 - 0.086 13.1 0.1 0.6 10.5 0.0 2.3 3 0 0 3 3 3 0 Tetratricopeptide repeat LRR_6 PF13516.6 OQS04567.1 - 4.3e-15 54.4 25.7 0.051 13.6 0.0 8.7 8 0 0 8 8 8 6 Leucine Rich repeat EF-hand_1 PF00036.32 OQS04567.1 - 1.4e-11 43.0 0.4 0.0001 21.6 0.1 3.1 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 OQS04567.1 - 9e-10 37.7 0.2 0.00013 21.6 0.1 3.4 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.6 OQS04567.1 - 2.5e-09 37.5 0.0 8.3e-09 35.8 0.0 2.0 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.6 OQS04567.1 - 1.6e-07 30.5 1.1 0.0011 18.4 0.2 2.6 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 OQS04567.1 - 5.9e-06 26.0 0.4 0.00023 20.9 0.1 3.1 2 1 1 3 3 3 2 EF-hand domain pair LRR_4 PF12799.7 OQS04567.1 - 7e-05 23.1 14.6 0.22 12.0 0.2 5.3 3 1 3 6 6 6 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 OQS04567.1 - 7.2e-05 22.8 6.8 29 5.7 0.0 7.5 9 0 0 9 9 9 0 Leucine Rich Repeat DUF4476 PF14771.6 OQS04567.1 - 0.00019 21.7 4.0 0.097 13.0 0.0 3.7 4 0 0 4 4 4 2 Domain of unknown function (DUF4476) LRR_8 PF13855.6 OQS04567.1 - 0.035 13.9 15.9 1.6 8.5 0.6 5.6 4 2 1 6 6 6 0 Leucine rich repeat Aminotran_3 PF00202.21 OQS04568.1 - 1e-120 403.2 0.0 1.2e-120 402.9 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Sulfotransfer_3 PF13469.6 OQS04569.1 - 9.7e-25 88.2 0.4 9.7e-25 88.2 0.4 2.9 3 1 1 4 4 4 1 Sulfotransferase family TFIIF_beta PF02270.15 OQS04569.1 - 0.018 15.2 0.1 0.052 13.7 0.1 1.8 1 0 0 1 1 1 0 TFIIF, beta subunit HTH domain THEG PF14912.6 OQS04569.1 - 0.076 13.5 0.5 0.45 11.0 0.5 2.4 1 0 0 1 1 1 0 Testicular haploid expressed repeat BCDHK_Adom3 PF10436.9 OQS04570.1 - 1.2e-55 187.8 0.1 1.6e-55 187.4 0.1 1.2 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 OQS04570.1 - 7.8e-13 48.9 0.0 3e-12 47.0 0.0 1.9 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 OQS04570.1 - 0.0054 16.6 0.0 0.0099 15.7 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF3338 PF11819.8 OQS04570.1 - 0.046 13.7 0.1 0.086 12.8 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3338) AICARFT_IMPCHas PF01808.18 OQS04571.1 - 4.4e-83 279.1 0.3 4.4e-83 279.1 0.3 1.6 2 0 0 2 2 2 1 AICARFT/IMPCHase bienzyme Pkinase PF00069.25 OQS04571.1 - 2.6e-26 92.6 0.2 7.2e-26 91.1 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain MGS PF02142.22 OQS04571.1 - 8.1e-26 90.0 0.0 2e-25 88.8 0.0 1.7 1 0 0 1 1 1 1 MGS-like domain Pkinase_Tyr PF07714.17 OQS04571.1 - 8.5e-15 54.7 0.1 6.7e-14 51.8 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OQS04571.1 - 1.2e-08 34.1 0.0 1.2e-08 34.1 0.0 1.6 2 0 0 2 2 2 1 Fungal protein kinase Pox_ser-thr_kin PF05445.11 OQS04571.1 - 0.012 14.7 0.1 0.02 13.8 0.1 1.3 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Spt20 PF12090.8 OQS04571.1 - 0.016 14.8 2.1 0.027 14.1 2.1 1.3 1 0 0 1 1 1 0 Spt20 family Med15 PF09606.10 OQS04571.1 - 0.023 13.4 14.3 0.035 12.8 14.3 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal APH PF01636.23 OQS04571.1 - 0.039 13.9 0.0 0.091 12.7 0.0 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family DJ-1_PfpI PF01965.24 OQS04572.1 - 3.7e-43 147.2 0.0 4.9e-43 146.8 0.0 1.2 1 0 0 1 1 1 1 DJ-1/PfpI family Ras PF00071.22 OQS04572.1 - 6.3e-43 146.2 0.1 9e-43 145.7 0.1 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OQS04572.1 - 7.2e-28 97.2 0.0 1.1e-27 96.7 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OQS04572.1 - 1.3e-11 44.3 0.0 2.3e-11 43.4 0.0 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 OQS04572.1 - 4.1e-05 23.6 0.0 8.9e-05 22.5 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 OQS04572.1 - 0.0013 18.3 0.0 0.01 15.4 0.0 2.0 1 1 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_24 PF13479.6 OQS04572.1 - 0.011 15.5 0.0 0.019 14.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain Gtr1_RagA PF04670.12 OQS04572.1 - 0.03 13.7 0.1 0.041 13.2 0.1 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region DHHC PF01529.20 OQS04573.1 - 1.1e-33 116.2 10.0 1.1e-33 116.2 10.0 2.1 2 0 0 2 2 2 1 DHHC palmitoyltransferase RPN7 PF10602.9 OQS04574.1 - 5.9e-42 143.3 0.2 1.4e-41 142.1 0.2 1.7 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.27 OQS04574.1 - 8.8e-19 68.0 2.6 1.8e-18 67.0 0.6 2.7 2 0 0 2 2 2 1 PCI domain DUF1664 PF07889.12 OQS04574.1 - 0.0014 18.7 1.4 0.0014 18.7 1.4 4.8 4 1 2 6 6 6 1 Protein of unknown function (DUF1664) Med9 PF07544.13 OQS04574.1 - 0.0079 16.3 7.4 0.059 13.5 0.2 3.8 2 1 0 2 2 2 1 RNA polymerase II transcription mediator complex subunit 9 AIP3 PF03915.13 OQS04574.1 - 0.23 10.5 27.0 0.22 10.6 3.4 3.8 3 1 0 3 3 3 0 Actin interacting protein 3 Spc42p PF11544.8 OQS04574.1 - 1.1 9.3 3.9 0.68 10.0 0.6 2.4 2 0 0 2 2 2 0 Spindle pole body component Spc42p Syntaxin-6_N PF09177.11 OQS04574.1 - 1.8 9.2 19.4 0.51 10.9 1.9 4.8 4 1 1 5 5 5 0 Syntaxin 6, N-terminal TolA_bind_tri PF16331.5 OQS04574.1 - 2.4 8.3 20.5 0.65 10.1 3.5 5.0 6 0 0 6 6 6 0 TolA binding protein trimerisation PIG-F PF06699.11 OQS04575.1 - 2.3e-30 106.1 6.1 3.4e-30 105.6 6.1 1.3 1 0 0 1 1 1 1 GPI biosynthesis protein family Pig-F O-antigen_lig PF13425.6 OQS04575.1 - 0.03 13.1 2.5 0.054 12.3 2.6 1.4 2 0 0 2 2 2 0 O-antigen ligase like membrane protein DUF4311 PF14188.6 OQS04575.1 - 8.6 6.1 11.4 36 4.0 0.1 2.5 2 1 1 3 3 3 0 Domain of unknown function (DUF4311) PCNA_C PF02747.15 OQS04576.1 - 2.3e-53 179.7 0.1 6.4e-53 178.3 0.0 1.7 2 0 0 2 2 2 1 Proliferating cell nuclear antigen, C-terminal domain PCNA_N PF00705.18 OQS04576.1 - 2.8e-49 166.1 0.4 4.9e-49 165.3 0.4 1.4 1 0 0 1 1 1 1 Proliferating cell nuclear antigen, N-terminal domain Rad1 PF02144.16 OQS04576.1 - 8.1e-06 25.1 0.0 2.1e-05 23.7 0.0 1.4 1 1 1 2 2 2 1 Repair protein Rad1/Rec1/Rad17 Rad9 PF04139.13 OQS04576.1 - 9.6e-06 25.2 0.0 1.3e-05 24.8 0.0 1.1 1 0 0 1 1 1 1 Rad9 CCD48 PF15799.5 OQS04576.1 - 0.023 13.1 0.0 0.032 12.6 0.0 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 48 Aa_trans PF01490.18 OQS04577.1 - 6.1e-63 212.9 30.8 7.2e-63 212.7 30.8 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein NADH-u_ox-rdase PF10785.9 OQS04577.1 - 0.097 13.4 0.8 0.31 11.8 0.1 2.4 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit Phage_holin_5_2 PF16079.5 OQS04577.1 - 0.38 11.1 0.1 0.38 11.1 0.1 3.6 3 0 0 3 3 3 0 Phage holin family Hol44, in holin superfamily V YrhC PF14143.6 OQS04577.1 - 0.92 9.6 7.5 0.55 10.3 0.6 3.5 3 0 0 3 3 3 0 YrhC-like protein Ank_2 PF12796.7 OQS04579.1 - 2e-47 159.6 6.8 3.8e-15 56.2 1.9 5.0 2 1 3 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQS04579.1 - 6.8e-38 128.6 4.0 2.1e-09 37.7 0.0 6.8 5 2 2 7 7 7 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQS04579.1 - 1.7e-34 114.0 9.1 0.0057 17.1 0.1 10.3 11 0 0 11 11 11 7 Ankyrin repeat Ank PF00023.30 OQS04579.1 - 4.4e-30 102.8 19.5 0.00049 20.4 0.1 10.2 10 1 0 10 10 10 7 Ankyrin repeat Ank_5 PF13857.6 OQS04579.1 - 1.1e-29 102.0 14.6 5.7e-09 36.1 0.3 7.3 5 4 3 8 8 8 7 Ankyrin repeats (many copies) Arm-DNA-bind_5 PF17293.2 OQS04579.1 - 0.11 13.0 0.0 64 4.1 0.0 3.6 3 1 0 3 3 3 0 Arm DNA-binding domain MobC PF05713.11 OQS04579.1 - 5.4 7.6 8.9 48 4.5 0.1 4.1 4 0 0 4 4 4 0 Bacterial mobilisation protein (MobC) DZR PF12773.7 OQS04580.1 - 0.017 15.2 1.4 0.023 14.7 1.4 1.3 1 0 0 1 1 1 0 Double zinc ribbon Anti-TRAP PF15777.5 OQS04580.1 - 0.095 12.7 0.3 0.095 12.7 0.3 1.8 1 1 1 2 2 2 0 Tryptophan RNA-binding attenuator protein inhibitory protein zf-ribbon_3 PF13248.6 OQS04580.1 - 1.8 8.1 6.6 17 5.0 6.8 2.1 1 1 0 1 1 1 0 zinc-ribbon domain Pkinase_Tyr PF07714.17 OQS04581.1 - 7.5e-27 94.2 0.0 1.4e-26 93.3 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OQS04581.1 - 4.8e-23 81.9 0.0 7.2e-23 81.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQS04582.1 - 5.6e-24 84.8 0.0 6.3e-24 84.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OQS04582.1 - 6.8e-23 81.4 0.0 7.3e-23 81.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 OQS04582.1 - 0.03 13.1 0.0 0.038 12.8 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase Kdo PF06293.14 OQS04582.1 - 0.033 13.5 0.0 0.042 13.2 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 OQS04582.1 - 0.042 13.1 0.0 0.046 13.0 0.0 1.1 1 0 0 1 1 1 0 Kinase-like DNA_pol_B_palm PF14792.6 OQS04583.1 - 1.9e-31 108.6 0.0 4.4e-31 107.4 0.0 1.7 1 0 0 1 1 1 1 DNA polymerase beta palm DNA_pol_lambd_f PF10391.9 OQS04583.1 - 1.8e-18 66.1 0.0 1.2e-17 63.5 0.0 2.4 3 0 0 3 3 3 1 Fingers domain of DNA polymerase lambda DNA_pol_B_thumb PF14791.6 OQS04583.1 - 2.6e-16 59.5 0.0 8.1e-16 57.9 0.0 1.9 1 0 0 1 1 1 1 DNA polymerase beta thumb DUSP PF06337.12 OQS04583.1 - 8.6e-16 58.3 0.0 2.5e-15 56.8 0.0 1.8 1 0 0 1 1 1 1 DUSP domain Acetyltransf_1 PF00583.25 OQS04583.1 - 2.1e-13 50.6 0.0 5.1e-13 49.3 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FYVE PF01363.21 OQS04583.1 - 5.3e-13 48.9 15.3 5.3e-13 48.9 15.3 1.9 2 0 0 2 2 2 1 FYVE zinc finger Acetyltransf_7 PF13508.7 OQS04583.1 - 1.1e-11 45.0 0.0 2.5e-11 43.8 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 OQS04583.1 - 2.9e-10 40.2 0.0 6.9e-10 38.9 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain HHH_8 PF14716.6 OQS04583.1 - 1.1e-06 28.9 0.0 1.1e-06 28.9 0.0 3.1 4 0 0 4 4 3 1 Helix-hairpin-helix domain FR47 PF08445.10 OQS04583.1 - 0.00012 22.0 0.0 0.00041 20.3 0.0 2.0 1 1 0 1 1 1 1 FR47-like protein HHH_5 PF14520.6 OQS04583.1 - 0.00018 22.0 0.0 0.00064 20.3 0.0 2.0 1 0 0 1 1 1 1 Helix-hairpin-helix domain Cdd1 PF11731.8 OQS04583.1 - 0.00031 20.9 0.0 0.00079 19.6 0.0 1.7 1 0 0 1 1 1 1 Pathogenicity locus NTP_transf_2 PF01909.23 OQS04583.1 - 0.0031 17.8 0.0 0.01 16.1 0.0 1.9 1 0 0 1 1 1 1 Nucleotidyltransferase domain BRCT PF00533.26 OQS04583.1 - 0.0055 17.1 0.1 0.021 15.2 0.0 2.1 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 OQS04583.1 - 0.02 15.3 0.0 0.048 14.1 0.0 1.6 1 0 0 1 1 1 0 BRCT domain, a BRCA1 C-terminus domain FYVE_2 PF02318.16 OQS04583.1 - 0.34 11.1 13.6 0.043 14.0 8.1 2.3 2 0 0 2 2 2 0 FYVE-type zinc finger Leu_zip PF15294.6 OQS04585.1 - 1.4e-26 93.6 27.6 6.6e-21 75.0 16.6 2.4 1 1 1 2 2 2 2 Leucine zipper KASH_CCD PF14662.6 OQS04585.1 - 0.0003 20.7 19.2 0.00077 19.3 19.2 1.7 1 1 0 1 1 1 1 Coiled-coil region of CCDC155 or KASH DUF4515 PF14988.6 OQS04585.1 - 0.00092 19.1 10.4 0.00092 19.1 10.4 2.7 1 1 2 3 3 3 1 Domain of unknown function (DUF4515) KLRAQ PF10205.9 OQS04585.1 - 0.0044 17.2 5.1 0.0044 17.2 5.1 3.2 2 2 0 3 3 3 1 Predicted coiled-coil domain-containing protein Spc7 PF08317.11 OQS04585.1 - 0.0045 15.9 20.3 0.0045 15.9 20.3 1.8 1 1 0 1 1 1 1 Spc7 kinetochore protein PKcGMP_CC PF16808.5 OQS04585.1 - 0.0073 16.1 0.7 0.0073 16.1 0.7 2.8 3 0 0 3 3 3 1 Coiled-coil N-terminus of cGMP-dependent protein kinase bZIP_2 PF07716.15 OQS04585.1 - 0.01 15.9 1.8 0.01 15.9 1.8 3.4 4 0 0 4 4 3 0 Basic region leucine zipper Tropomyosin_1 PF12718.7 OQS04585.1 - 0.034 14.3 26.2 0.034 14.3 14.8 2.8 2 1 1 3 3 3 0 Tropomyosin like FlaC_arch PF05377.11 OQS04585.1 - 0.063 13.7 7.6 1.3 9.5 0.1 4.3 3 1 0 3 3 3 0 Flagella accessory protein C (FlaC) GIT_CC PF16559.5 OQS04585.1 - 0.11 12.4 8.9 0.82 9.6 0.7 2.7 2 0 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor SlyX PF04102.12 OQS04585.1 - 0.14 12.8 20.7 2.4 8.8 2.1 4.2 2 2 2 4 4 4 0 SlyX XPC-binding PF09280.11 OQS04585.1 - 0.15 11.8 0.2 0.15 11.8 0.2 1.9 2 0 0 2 2 2 0 XPC-binding domain NYD-SP28 PF14772.6 OQS04585.1 - 0.44 10.6 22.3 3.1 7.9 5.6 3.5 2 1 1 3 3 3 0 Sperm tail FUSC PF04632.12 OQS04585.1 - 0.45 9.0 11.2 0.29 9.6 9.5 1.4 1 1 0 1 1 1 0 Fusaric acid resistance protein family Sec34 PF04136.15 OQS04585.1 - 0.69 9.8 16.8 0.11 12.4 2.4 2.8 2 1 1 3 3 3 0 Sec34-like family Filament PF00038.21 OQS04585.1 - 0.81 9.2 28.4 0.24 10.9 7.4 2.4 1 1 1 2 2 2 0 Intermediate filament protein Uds1 PF15456.6 OQS04585.1 - 0.84 9.8 19.4 0.1 12.8 14.3 2.0 2 1 0 2 2 2 0 Up-regulated During Septation bZIP_1 PF00170.21 OQS04585.1 - 1.1 9.4 12.6 0.12 12.5 2.2 3.6 2 2 1 3 3 3 0 bZIP transcription factor FRB_dom PF08771.11 OQS04585.1 - 1.1 9.7 6.9 0.39 11.2 1.6 2.8 2 1 1 3 3 3 0 FKBP12-rapamycin binding domain NEMO PF11577.8 OQS04585.1 - 1.4 9.0 12.9 0.38 10.8 3.5 3.2 2 1 1 3 3 3 0 NF-kappa-B essential modulator NEMO Med9 PF07544.13 OQS04585.1 - 1.5 9.0 13.0 4.4 7.5 5.2 3.2 2 1 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 Tup_N PF08581.10 OQS04585.1 - 1.6 9.0 20.8 2.6 8.4 2.8 3.4 2 1 1 3 3 3 0 Tup N-terminal Angiomotin_C PF12240.8 OQS04585.1 - 1.7 8.1 22.8 2 7.9 5.1 3.2 1 1 2 3 3 3 0 Angiomotin C terminal HALZ PF02183.18 OQS04585.1 - 1.8 8.9 12.2 0.25 11.6 1.0 3.6 3 1 1 4 4 2 0 Homeobox associated leucine zipper Myc-LZ PF02344.15 OQS04585.1 - 2.5 8.3 10.4 0.068 13.3 2.9 2.4 2 1 0 2 2 1 0 Myc leucine zipper domain DUF1382 PF07131.11 OQS04585.1 - 2.5 8.2 6.6 2.9 8.0 0.1 3.3 4 0 0 4 4 2 0 Protein of unknown function (DUF1382) TolA_bind_tri PF16331.5 OQS04585.1 - 2.7 8.2 17.0 0.39 10.8 6.9 3.3 1 1 1 2 2 2 0 TolA binding protein trimerisation TBCA PF02970.16 OQS04585.1 - 2.7 8.4 19.0 2 8.8 6.8 3.2 2 1 0 3 3 3 0 Tubulin binding cofactor A YabA PF06156.13 OQS04585.1 - 2.9 8.6 17.8 1.1 10.0 6.7 3.4 1 1 3 4 4 4 0 Initiation control protein YabA FlxA PF14282.6 OQS04585.1 - 4.7 7.3 18.6 12 5.9 3.3 2.8 1 1 1 2 2 2 0 FlxA-like protein UPF0242 PF06785.11 OQS04585.1 - 5.1 7.2 26.4 2.6e+02 1.6 26.1 2.6 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus TMF_DNA_bd PF12329.8 OQS04585.1 - 6.2 6.9 22.6 1 9.4 1.0 4.0 2 1 2 4 4 4 0 TATA element modulatory factor 1 DNA binding THOC7 PF05615.13 OQS04585.1 - 6.5 7.0 22.5 0.71 10.1 4.5 3.1 1 1 2 3 3 3 0 Tho complex subunit 7 Rav1p_C PF12234.8 OQS04586.1 - 6.1e-34 117.4 0.0 9e-34 116.9 0.0 1.2 1 0 0 1 1 1 1 RAVE protein 1 C terminal C2 PF00168.30 OQS04586.1 - 0.00019 21.7 0.0 0.88 9.9 0.0 2.7 2 0 0 2 2 2 2 C2 domain DEP PF00610.21 OQS04586.1 - 0.00083 19.4 0.1 0.003 17.6 0.1 1.9 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) DUF4205 PF13898.6 OQS04587.1 - 1.1e-54 185.7 0.0 2.3e-49 168.2 0.0 2.9 2 1 0 2 2 2 2 Domain of unknown function (DUF4205) EF-hand_6 PF13405.6 OQS04587.1 - 0.0083 16.0 1.7 0.14 12.2 0.0 3.3 3 0 0 3 3 3 1 EF-hand domain EF-hand_7 PF13499.6 OQS04587.1 - 0.011 16.2 0.0 0.082 13.4 0.0 2.5 3 0 0 3 3 3 0 EF-hand domain pair Pkinase PF00069.25 OQS04588.1 - 1.3e-48 165.7 0.1 1.8e-48 165.2 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQS04588.1 - 1.7e-31 109.5 0.1 2.3e-31 109.0 0.1 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 OQS04588.1 - 0.00023 20.6 0.2 0.00037 19.9 0.2 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 OQS04588.1 - 0.00029 19.9 0.1 0.00037 19.5 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 OQS04588.1 - 0.0026 16.6 0.1 0.0048 15.7 0.1 1.4 1 0 0 1 1 1 1 Fungal protein kinase RIO1 PF01163.22 OQS04588.1 - 0.0054 16.3 0.2 0.014 15.0 0.2 1.8 1 1 0 1 1 1 1 RIO1 family Kinase-like PF14531.6 OQS04588.1 - 0.0093 15.3 0.0 0.012 15.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 OQS04588.1 - 0.042 13.8 0.1 0.064 13.2 0.1 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase_Tyr PF07714.17 OQS04590.1 - 6.7e-54 182.9 0.0 8.6e-54 182.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OQS04590.1 - 6.7e-51 173.2 0.0 9.1e-51 172.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain LRR_4 PF12799.7 OQS04590.1 - 4.6e-09 36.4 12.4 1.2e-05 25.6 0.1 3.2 3 0 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 OQS04590.1 - 2.5e-08 33.6 12.6 7.1e-06 25.7 5.0 3.4 1 1 2 3 3 3 3 Leucine rich repeat SKG6 PF08693.10 OQS04590.1 - 5.3e-05 22.5 2.4 0.00011 21.5 2.4 1.6 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Haspin_kinase PF12330.8 OQS04590.1 - 0.0035 16.3 0.0 0.0075 15.2 0.0 1.5 1 0 0 1 1 1 1 Haspin like kinase domain LRR_6 PF13516.6 OQS04590.1 - 0.022 14.8 11.3 14 6.0 0.1 4.7 4 0 0 4 4 4 0 Leucine Rich repeat Podoplanin PF05808.11 OQS04590.1 - 0.028 14.5 0.4 0.064 13.4 0.4 1.6 1 0 0 1 1 1 0 Podoplanin APH PF01636.23 OQS04590.1 - 0.043 13.7 0.0 0.086 12.7 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.14 OQS04590.1 - 0.065 12.6 0.0 0.1 11.9 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family EphA2_TM PF14575.6 OQS04590.1 - 0.1 13.5 0.0 0.19 12.6 0.0 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain PTP_tm PF18861.1 OQS04590.1 - 0.15 12.1 2.0 0.32 10.9 2.0 1.6 1 0 0 1 1 1 0 Transmembrane domain of protein tyrosine phosphatase, receptor type J Adeno_E3_CR2 PF02439.15 OQS04590.1 - 0.21 11.4 1.5 0.55 10.0 1.5 1.7 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Cut8 PF08559.10 OQS04590.1 - 1.1 8.8 4.0 0.39 10.3 0.5 1.9 2 0 0 2 2 2 0 Cut8, nuclear proteasome tether protein LRR_1 PF00560.33 OQS04590.1 - 1.1 10.0 11.6 3.3 8.6 0.0 5.2 5 2 0 5 5 4 0 Leucine Rich Repeat PsbX PF06596.11 OQS04590.1 - 2.9 8.0 6.5 6.7 6.8 6.5 1.6 1 0 0 1 1 1 0 Photosystem II reaction centre X protein (PsbX) DUF3074 PF11274.8 OQS04591.1 - 0.00097 19.2 0.0 0.0017 18.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3074) UCH PF00443.29 OQS04592.1 - 4.6e-66 222.9 0.2 9.1e-66 222.0 0.0 1.6 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase 2OG-FeII_Oxy_3 PF13640.6 OQS04592.1 - 4.9e-17 62.6 0.0 1.5e-16 61.0 0.0 1.9 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily UCH_1 PF13423.6 OQS04592.1 - 1.6e-11 44.4 4.2 4.4e-05 23.2 0.7 2.4 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase 2OG-FeII_Oxy_4 PF13661.6 OQS04592.1 - 4.5e-09 36.8 0.0 1.6e-08 35.1 0.0 2.0 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily DUSP PF06337.12 OQS04592.1 - 3.2e-08 34.1 0.3 1.7e-07 31.8 0.0 2.4 3 0 0 3 3 3 1 DUSP domain USP7_C2 PF14533.6 OQS04592.1 - 0.00051 19.8 0.0 0.0012 18.6 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin-specific protease C-terminal Spore_Cse60 PF10957.8 OQS04592.1 - 0.0049 16.9 0.1 0.26 11.4 0.0 2.8 2 0 0 2 2 2 1 Sporulation protein Cse60 NinB PF05772.12 OQS04592.1 - 0.17 11.7 0.0 0.43 10.4 0.0 1.7 1 0 0 1 1 1 0 NinB protein Oxygenase-NA PF09859.9 OQS04592.1 - 0.22 11.0 0.6 2.3 7.7 0.1 2.5 3 0 0 3 3 3 0 Oxygenase, catalysing oxidative methylation of damaged DNA EphA2_TM PF14575.6 OQS04593.1 - 0.018 15.9 0.0 0.035 15.0 0.0 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Kinesin PF00225.23 OQS04594.1 - 5.5e-100 334.5 1.2 5.5e-100 334.5 1.2 1.9 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 OQS04594.1 - 5.8e-27 94.5 0.1 2.8e-26 92.2 0.1 2.3 1 0 0 1 1 1 1 Microtubule binding ZZ PF00569.17 OQS04594.1 - 2.4e-14 52.9 25.1 4.5e-07 29.6 11.4 2.5 2 0 0 2 2 2 2 Zinc finger, ZZ type C1_2 PF03107.16 OQS04594.1 - 1.9e-05 24.8 23.6 0.00012 22.4 3.2 2.8 2 0 0 2 2 2 2 C1 domain Cyclin PF08613.11 OQS04594.1 - 0.048 14.0 0.7 23 5.3 0.0 3.2 3 0 0 3 3 3 0 Cyclin UpxZ PF06603.11 OQS04594.1 - 0.68 10.3 6.5 0.21 11.9 2.0 2.6 2 0 0 2 2 2 0 UpxZ family of transcription anti-terminator antagonists Pkinase PF00069.25 OQS04595.1 - 1.1e-93 313.5 0.0 2.5e-49 168.0 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OQS04595.1 - 4.1e-54 183.6 0.0 5e-26 91.5 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 OQS04595.1 - 7.9e-10 38.1 0.1 2.4e-05 23.3 0.1 2.7 2 1 0 2 2 2 2 Fungal protein kinase Haspin_kinase PF12330.8 OQS04595.1 - 1.1e-09 37.8 0.8 0.00013 21.1 0.0 2.2 2 0 0 2 2 2 2 Haspin like kinase domain APH PF01636.23 OQS04595.1 - 4.8e-07 30.0 2.8 0.085 12.8 0.5 4.1 2 2 2 4 4 4 2 Phosphotransferase enzyme family Kdo PF06293.14 OQS04595.1 - 1.9e-06 27.4 0.5 0.01 15.2 0.2 2.2 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 OQS04595.1 - 3e-06 26.9 0.0 0.01 15.4 0.0 2.5 2 0 0 2 2 2 2 RIO1 family mRNA_cap_enzyme PF01331.19 OQS04596.1 - 2.2e-15 57.0 0.0 4e-15 56.2 0.0 1.4 1 1 0 1 1 1 1 mRNA capping enzyme, catalytic domain mRNA_cap_C PF03919.15 OQS04596.1 - 4.3e-06 27.3 0.1 2.7e-05 24.8 0.1 2.1 1 1 0 1 1 1 1 mRNA capping enzyme, C-terminal domain zf-CCCH PF00642.24 OQS04596.1 - 0.00035 20.4 6.4 0.00067 19.5 6.4 1.5 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 OQS04596.1 - 0.00048 20.1 6.2 0.00098 19.1 6.2 1.6 1 0 0 1 1 1 1 Zinc finger domain Clat_adaptor_s PF01217.20 OQS04597.1 - 8.6e-18 64.6 0.5 1e-17 64.4 0.5 1.1 1 0 0 1 1 1 1 Clathrin adaptor complex small chain DUF4024 PF13216.6 OQS04597.1 - 0.00042 20.2 0.1 0.00085 19.2 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF4024) NAC PF01849.18 OQS04597.1 - 0.044 13.8 0.3 0.099 12.6 0.2 1.7 1 1 0 1 1 1 0 NAC domain NIF PF03031.18 OQS04597.1 - 0.062 13.1 0.0 0.095 12.5 0.0 1.3 1 0 0 1 1 1 0 NLI interacting factor-like phosphatase Pkinase PF00069.25 OQS04598.1 - 5.9e-45 153.7 0.0 8.7e-31 107.2 0.0 2.4 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OQS04598.1 - 2.1e-24 86.2 0.0 5.4e-18 65.2 0.0 2.7 2 1 0 2 2 2 2 Protein tyrosine kinase ATG16 PF08614.11 OQS04598.1 - 0.0033 17.7 3.0 0.0063 16.8 3.0 1.5 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) Kinase-like PF14531.6 OQS04598.1 - 0.0034 16.7 0.0 0.008 15.5 0.0 1.6 1 0 0 1 1 1 1 Kinase-like DivIC PF04977.15 OQS04598.1 - 0.017 14.9 2.4 0.035 13.9 2.4 1.5 1 0 0 1 1 1 0 Septum formation initiator FTA2 PF13095.6 OQS04598.1 - 0.056 13.1 0.1 5.4 6.6 0.0 2.4 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 DUF3837 PF12939.7 OQS04598.1 - 0.19 12.1 0.5 0.45 10.9 0.5 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3837) APH PF01636.23 OQS04598.1 - 0.29 11.0 2.0 0.8 9.6 0.1 2.2 2 0 0 2 2 2 0 Phosphotransferase enzyme family PKcGMP_CC PF16808.5 OQS04598.1 - 2.1 8.2 5.5 2.2 8.2 1.6 2.8 2 1 1 3 3 3 0 Coiled-coil N-terminus of cGMP-dependent protein kinase PIH1_CS PF18201.1 OQS04599.1 - 8.9e-13 48.5 0.0 1.2e-12 48.1 0.0 1.2 1 0 0 1 1 1 1 PIH1 CS-like domain Acetyltransf_3 PF13302.7 OQS04601.1 - 2.2e-22 80.2 0.3 4.7e-22 79.2 0.3 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 OQS04601.1 - 6.6e-07 29.1 0.4 1.8e-06 27.7 0.4 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 OQS04601.1 - 5.1e-05 23.5 0.0 0.00024 21.3 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family FR47 PF08445.10 OQS04601.1 - 0.0015 18.4 0.0 0.0048 16.8 0.0 1.8 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_4 PF13420.7 OQS04601.1 - 0.0025 18.0 0.2 0.0058 16.8 0.2 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Pox_Ag35 PF03286.14 OQS04601.1 - 0.25 11.1 4.9 0.53 10.1 4.9 1.5 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Actin PF00022.19 OQS04602.1 - 9.4e-65 218.8 0.0 1e-64 218.6 0.0 1.0 1 0 0 1 1 1 1 Actin MT-A70 PF05063.14 OQS04603.1 - 1.6e-32 112.8 0.0 2.1e-32 112.4 0.0 1.1 1 0 0 1 1 1 1 MT-A70 RMI1_N PF08585.12 OQS04604.1 - 3.1e-28 99.0 4.8 2.2e-19 70.1 0.1 3.0 1 1 2 3 3 3 2 RecQ mediated genome instability protein RMI1_C PF16099.5 OQS04604.1 - 3.4e-20 72.3 0.2 8.6e-20 71.0 0.0 1.8 2 0 0 2 2 2 1 Recq-mediated genome instability protein 1, C-terminal OB-fold DUF5130 PF17174.4 OQS04604.1 - 0.097 12.9 0.0 0.22 11.8 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5130) RRM_1 PF00076.22 OQS04605.1 - 5.7e-16 58.1 0.0 9.1e-16 57.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCHC PF00098.23 OQS04605.1 - 5.7e-05 23.0 2.0 5.7e-05 23.0 2.0 2.0 2 1 0 2 2 2 1 Zinc knuckle RRM_5 PF13893.6 OQS04605.1 - 0.0048 16.5 0.0 0.0064 16.1 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCHC_3 PF13917.6 OQS04605.1 - 0.023 14.7 1.7 0.042 13.8 1.7 1.5 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_2 PF13696.6 OQS04605.1 - 0.082 12.7 0.6 0.16 11.9 0.6 1.5 1 0 0 1 1 1 0 Zinc knuckle RNA_bind PF08675.11 OQS04605.1 - 0.13 12.3 0.0 0.25 11.4 0.0 1.5 1 1 0 1 1 1 0 RNA binding domain PMSR PF01625.21 OQS04606.1 - 1.9e-63 213.2 4.6 2.3e-63 212.9 4.6 1.0 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase Ank_2 PF12796.7 OQS04607.1 - 4.6e-11 43.2 1.3 2.5e-06 28.0 0.3 2.5 1 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQS04607.1 - 2.7e-07 31.0 0.3 0.0017 18.9 0.0 3.0 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQS04607.1 - 5.4e-06 26.4 0.7 28 5.7 0.0 5.0 4 1 1 5 5 5 0 Ankyrin repeat Ank_5 PF13857.6 OQS04607.1 - 0.00023 21.4 1.5 2.1 8.8 0.0 4.1 1 1 4 5 5 5 1 Ankyrin repeats (many copies) DUF5049 PF16468.5 OQS04607.1 - 0.028 14.3 0.9 14 5.7 0.2 3.3 1 1 2 3 3 3 0 Domain of unknown function (DUF5049) Endonuclease_NS PF01223.23 OQS04607.1 - 0.031 14.1 0.0 0.041 13.7 0.0 1.1 1 0 0 1 1 1 0 DNA/RNA non-specific endonuclease Ank PF00023.30 OQS04607.1 - 0.15 12.5 0.8 72 4.1 0.0 3.6 2 1 1 3 3 3 0 Ankyrin repeat Ank_2 PF12796.7 OQS04608.1 - 5.6e-09 36.5 1.1 2.3e-05 24.9 0.4 3.3 2 1 2 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQS04608.1 - 9.5e-08 32.4 4.3 0.0036 17.9 0.6 4.3 2 1 4 6 6 6 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 OQS04608.1 - 1.3e-05 25.4 3.2 0.64 10.4 0.0 4.3 2 1 2 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQS04608.1 - 5.6e-05 23.2 4.4 15 6.6 0.1 5.8 6 0 0 6 6 6 1 Ankyrin repeat DUF3447 PF11929.8 OQS04608.1 - 0.21 11.6 0.5 20 5.2 0.0 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF3447) Ank_2 PF12796.7 OQS04609.1 - 2e-16 60.3 0.5 5.1e-06 27.0 0.0 4.0 1 1 4 5 5 5 4 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OQS04609.1 - 5.1e-14 52.2 0.2 0.15 12.4 0.0 7.1 2 1 5 7 7 7 4 Ankyrin repeats (many copies) Ank_4 PF13637.6 OQS04609.1 - 7.6e-13 48.7 2.7 0.047 14.3 0.0 6.3 3 2 2 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQS04609.1 - 2.5e-12 45.8 0.3 16 6.4 0.0 7.4 6 1 1 7 7 7 4 Ankyrin repeat Ank PF00023.30 OQS04609.1 - 5.3e-05 23.5 0.6 7.1 7.3 0.1 5.7 4 2 0 4 4 4 1 Ankyrin repeat DUF249 PF03158.13 OQS04609.1 - 0.043 13.5 0.4 0.36 10.5 0.4 2.3 1 1 0 1 1 1 0 Multigene family 530 protein Ank_2 PF12796.7 OQS04610.1 - 3e-10 40.5 3.7 0.0015 19.1 0.2 3.5 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQS04610.1 - 2.7e-08 34.2 1.7 0.077 13.6 0.1 4.3 2 2 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQS04610.1 - 1e-06 28.6 0.2 21 6.1 0.0 5.7 6 0 0 6 6 6 1 Ankyrin repeat Ank_5 PF13857.6 OQS04610.1 - 1.8e-05 24.9 3.6 14 6.2 0.0 5.5 2 2 4 6 6 6 3 Ankyrin repeats (many copies) CHAD PF05235.14 OQS04610.1 - 0.01 15.9 0.1 0.1 12.5 0.0 2.0 2 0 0 2 2 2 0 CHAD domain Lipocalin PF00061.23 OQS04610.1 - 0.054 13.7 0.6 3.4 7.9 0.2 2.4 1 1 1 2 2 2 0 Lipocalin / cytosolic fatty-acid binding protein family Aminotran_1_2 PF00155.21 OQS04611.1 - 2.3e-103 346.2 0.2 1.7e-51 175.5 0.1 2.4 2 0 0 2 2 2 2 Aminotransferase class I and II WD40 PF00400.32 OQS04611.1 - 1.5e-49 164.9 50.3 0.00019 22.1 0.0 21.0 22 0 0 22 22 20 12 WD domain, G-beta repeat HELP PF03451.14 OQS04611.1 - 3.5e-41 138.9 0.1 5.8e-15 54.9 0.0 3.6 3 0 0 3 3 3 3 HELP motif ANAPC4_WD40 PF12894.7 OQS04611.1 - 3.7e-16 59.2 0.4 0.13 12.5 0.0 10.9 7 4 3 11 11 10 2 Anaphase-promoting complex subunit 4 WD40 domain Beta_elim_lyase PF01212.21 OQS04611.1 - 9.8e-08 31.6 0.3 9.4e-06 25.1 0.1 2.3 2 0 0 2 2 2 1 Beta-eliminating lyase Aminotran_5 PF00266.19 OQS04611.1 - 6e-07 28.7 0.0 0.023 13.7 0.0 2.3 2 0 0 2 2 2 2 Aminotransferase class-V EF-hand_6 PF13405.6 OQS04611.1 - 1.1e-06 28.1 0.4 0.47 10.5 0.0 4.0 3 0 0 3 3 3 2 EF-hand domain EF-hand_1 PF00036.32 OQS04611.1 - 2e-06 26.9 0.6 1.1 9.0 0.0 3.8 3 0 0 3 3 3 2 EF hand PX PF00787.24 OQS04611.1 - 5.4e-06 26.4 0.1 1.2e-05 25.2 0.1 1.6 1 0 0 1 1 1 1 PX domain DegT_DnrJ_EryC1 PF01041.17 OQS04611.1 - 6.7e-06 25.6 0.7 0.00035 20.0 0.0 2.3 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family EF-hand_7 PF13499.6 OQS04611.1 - 8.9e-06 26.1 0.0 0.00085 19.7 0.0 2.8 2 0 0 2 2 2 1 EF-hand domain pair Frtz PF11768.8 OQS04611.1 - 1.1e-05 23.9 0.2 0.14 10.5 0.0 3.7 4 0 0 4 4 4 2 WD repeat-containing and planar cell polarity effector protein Fritz WD40_like PF17005.5 OQS04611.1 - 2.8e-05 23.6 2.9 0.28 10.5 0.0 4.3 5 0 0 5 5 5 2 WD40-like domain Cytochrom_D1 PF02239.16 OQS04611.1 - 0.00036 19.2 0.1 0.035 12.6 0.0 3.2 3 0 0 3 3 3 1 Cytochrome D1 heme domain Ge1_WD40 PF16529.5 OQS04611.1 - 0.00048 19.2 4.0 1.5 7.7 0.0 5.0 4 1 1 5 5 5 1 WD40 region of Ge1, enhancer of mRNA-decapping protein OKR_DC_1 PF01276.20 OQS04611.1 - 0.0062 15.3 0.0 0.012 14.3 0.0 1.4 1 0 0 1 1 1 1 Orn/Lys/Arg decarboxylase, major domain EF-hand_5 PF13202.6 OQS04611.1 - 0.084 12.4 0.7 3.8 7.2 0.0 2.9 2 0 0 2 2 2 0 EF hand PQQ_3 PF13570.6 OQS04611.1 - 0.12 12.9 1.4 81 3.9 0.0 5.5 5 0 0 5 5 4 0 PQQ-like domain SNase PF00565.17 OQS04612.1 - 6.5e-68 226.0 0.1 1e-17 64.6 0.0 5.4 5 0 0 5 5 5 5 Staphylococcal nuclease homologue TUDOR PF00567.24 OQS04612.1 - 1.7e-19 70.0 0.0 3.6e-19 69.0 0.0 1.5 1 0 0 1 1 1 1 Tudor domain TFA2_Winged_2 PF18121.1 OQS04612.1 - 0.039 13.6 0.0 0.091 12.5 0.0 1.6 1 0 0 1 1 1 0 TFA2 Winged helix domain 2 zf-MYND PF01753.18 OQS04613.1 - 2.4e-10 40.3 16.4 4.5e-10 39.5 16.4 1.5 1 0 0 1 1 1 1 MYND finger zf-C6H2 PF15801.5 OQS04613.1 - 0.0098 16.2 13.2 0.02 15.2 13.2 1.5 1 0 0 1 1 1 1 zf-MYND-like zinc finger, mRNA-binding E1_dh PF00676.20 OQS04614.1 - 1e-86 290.6 0.0 1.3e-86 290.2 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component TPP_enzyme_C PF02775.21 OQS04614.1 - 7.7e-06 25.8 0.0 0.00013 21.8 0.0 2.2 1 1 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain DXP_synthase_N PF13292.6 OQS04614.1 - 0.012 14.9 0.0 0.049 12.8 0.0 1.9 2 0 0 2 2 2 0 1-deoxy-D-xylulose-5-phosphate synthase Cation_efflux PF01545.21 OQS04615.1 - 1.3e-45 155.6 12.1 1.3e-45 155.6 12.1 3.1 2 1 0 2 2 2 1 Cation efflux family Atg29_N PF18388.1 OQS04615.1 - 0.18 11.7 0.0 0.36 10.7 0.0 1.4 1 0 0 1 1 1 0 Atg29 N-terminal domain Sel1 PF08238.12 OQS04616.1 - 1.5e-21 76.3 9.0 8.9e-07 29.4 0.0 6.3 6 0 0 6 6 6 4 Sel1 repeat ABC2_membrane PF01061.24 OQS04617.1 - 3.3e-36 124.7 25.6 7.2e-36 123.6 23.8 2.2 2 0 0 2 2 2 1 ABC-2 type transporter ABC_tran PF00005.27 OQS04617.1 - 9.1e-25 87.8 0.0 1.6e-24 87.0 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 OQS04617.1 - 3e-06 27.3 0.0 0.031 14.1 0.0 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system ABC2_membrane_3 PF12698.7 OQS04617.1 - 7.9e-05 21.9 23.2 7.9e-05 21.9 23.2 1.8 1 1 0 1 1 1 1 ABC-2 family transporter protein AAA_29 PF13555.6 OQS04617.1 - 0.00046 19.9 2.1 0.0054 16.4 0.6 3.1 3 0 0 3 3 3 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 OQS04617.1 - 0.00075 19.4 0.8 0.0032 17.4 0.3 2.1 2 0 0 2 2 2 1 RsgA GTPase SMC_N PF02463.19 OQS04617.1 - 0.0024 17.4 0.3 0.67 9.3 0.0 2.3 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 OQS04617.1 - 0.0067 16.8 0.1 0.016 15.6 0.1 1.7 1 1 0 1 1 1 1 AAA ATPase domain MeaB PF03308.16 OQS04617.1 - 0.01 14.8 0.3 0.019 14.0 0.3 1.3 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA PF00004.29 OQS04617.1 - 0.023 15.1 0.2 0.22 11.9 0.2 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_23 PF13476.6 OQS04617.1 - 0.046 14.2 0.6 0.083 13.4 0.6 1.3 1 0 0 1 1 1 0 AAA domain T2SSE PF00437.20 OQS04617.1 - 0.048 12.7 0.4 0.084 11.9 0.4 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_25 PF13481.6 OQS04617.1 - 0.082 12.5 0.1 0.24 11.0 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 OQS04617.1 - 0.096 12.8 0.0 0.2 11.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain cobW PF02492.19 OQS04617.1 - 0.1 12.2 1.4 0.21 11.2 1.4 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_28 PF13521.6 OQS04617.1 - 0.1 12.8 1.1 0.19 12.0 1.1 1.3 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 OQS04617.1 - 0.1 12.9 0.0 0.23 11.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 OQS04617.1 - 0.17 11.6 0.6 0.35 10.6 0.6 1.4 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 OQS04617.1 - 0.22 12.1 0.0 0.48 11.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 OQS04617.1 - 0.71 10.0 2.4 0.53 10.4 0.5 1.8 2 0 0 2 2 1 0 50S ribosome-binding GTPase Myb_DNA-binding PF00249.31 OQS04618.1 - 3.4e-09 36.7 0.1 5.5e-09 36.1 0.1 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OQS04618.1 - 0.037 14.3 0.4 0.06 13.6 0.4 1.4 1 0 0 1 1 1 0 Myb-like DNA-binding domain SnAPC_2_like PF11035.8 OQS04618.1 - 0.053 13.7 0.1 0.069 13.3 0.1 1.1 1 0 0 1 1 1 0 Small nuclear RNA activating complex subunit 2, SNAP190 Myb Dimeth_Pyl PF09505.10 OQS04618.1 - 0.076 11.5 0.0 0.1 11.1 0.0 1.2 1 0 0 1 1 1 0 Dimethylamine methyltransferase (Dimeth_PyL) EAP30 PF04157.16 OQS04618.1 - 0.077 12.3 0.0 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 EAP30/Vps36 family TEA PF01285.18 OQS04618.1 - 0.1 12.7 0.3 5.4 7.2 0.0 2.3 1 1 1 2 2 2 0 TEA/ATTS domain PX PF00787.24 OQS04619.1 - 1.5e-10 41.1 1.2 3.4e-10 39.9 1.2 1.6 1 0 0 1 1 1 1 PX domain Mito_carr PF00153.27 OQS04620.1 - 5.5e-50 167.2 2.1 3.8e-17 62.0 0.2 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF4148 PF13663.6 OQS04620.1 - 0.068 13.4 1.9 0.47 10.7 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4148) Myb_DNA-binding PF00249.31 OQS04621.1 - 1.3e-08 34.9 0.2 1.3e-08 34.9 0.2 1.9 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OQS04621.1 - 0.061 13.6 0.1 0.13 12.6 0.1 1.5 1 1 0 1 1 1 0 Myb-like DNA-binding domain Thioredoxin_8 PF13905.6 OQS04622.1 - 7.4e-39 132.0 11.0 3.6e-10 40.1 0.2 4.5 4 0 0 4 4 4 4 Thioredoxin-like Redoxin PF08534.10 OQS04622.1 - 3.9e-18 65.6 2.2 8e-06 25.6 0.0 4.2 4 0 0 4 4 4 4 Redoxin AhpC-TSA PF00578.21 OQS04622.1 - 1.4e-15 57.3 2.0 1.6e-05 24.8 0.0 4.4 4 0 0 4 4 4 3 AhpC/TSA family Thioredoxin PF00085.20 OQS04622.1 - 1.1e-14 54.2 2.0 7.9e-06 25.8 0.1 4.5 4 1 1 5 5 5 2 Thioredoxin Thioredoxin_2 PF13098.6 OQS04622.1 - 1.2e-10 41.8 0.4 0.00086 19.7 0.0 3.1 2 0 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_9 PF14595.6 OQS04622.1 - 1.4e-09 37.8 0.3 0.0047 16.7 0.0 3.7 2 2 0 2 2 2 2 Thioredoxin NUP PF06516.11 OQS04622.1 - 3e-05 23.4 1.2 0.0065 15.7 0.2 2.3 2 0 0 2 2 2 2 Purine nucleoside permease (NUP) Thioredoxin_4 PF13462.6 OQS04622.1 - 9.9e-05 22.6 0.1 0.18 11.9 0.0 2.7 2 0 0 2 2 2 2 Thioredoxin DUF953 PF06110.11 OQS04622.1 - 0.00074 19.1 1.5 2.1 8.0 0.1 3.4 2 2 0 2 2 2 2 Eukaryotic protein of unknown function (DUF953) GSH_synthase PF03199.15 OQS04622.1 - 0.03 14.8 2.3 29 5.2 0.0 4.4 5 0 0 5 5 5 0 Eukaryotic glutathione synthase Thioredoxin_7 PF13899.6 OQS04622.1 - 0.055 13.7 0.1 7.9 6.7 0.0 3.0 2 0 0 2 2 2 0 Thioredoxin-like DUF4250 PF14056.6 OQS04622.1 - 0.076 13.0 0.2 13 5.9 0.1 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4250) DUF3991 PF13154.6 OQS04622.1 - 0.079 13.3 0.1 25 5.3 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3991) HTH_ABP1_N PF18107.1 OQS04622.1 - 0.088 12.5 0.5 2.4 7.9 0.1 2.4 2 0 0 2 2 2 0 Fission yeast centromere protein N-terminal domain Homez PF11569.8 OQS04622.1 - 0.12 11.8 0.1 15 5.2 0.0 2.7 2 0 0 2 2 2 0 Homeodomain leucine-zipper encoding, Homez HscB_4_cys PF18256.1 OQS04622.1 - 0.27 11.1 2.7 4.2 7.3 0.2 2.5 2 0 0 2 2 2 0 Co-chaperone HscB tetracysteine metal binding motif Ribosom_S30AE_C PF16321.5 OQS04622.1 - 1.1 9.0 5.0 29 4.5 0.2 3.7 4 0 0 4 4 4 0 Sigma 54 modulation/S30EA ribosomal protein C terminus Tetraspanin PF00335.20 OQS04623.1 - 1.9e-15 57.2 14.9 3.8e-15 56.2 14.9 1.5 1 1 0 1 1 1 1 Tetraspanin family DUF2981 PF11200.8 OQS04623.1 - 0.02 14.6 7.1 0.038 13.7 7.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2981) DUF373 PF04123.13 OQS04623.1 - 0.16 11.3 11.1 0.087 12.3 8.5 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF373) DUF3043 PF11241.8 OQS04623.1 - 1.6 8.7 3.9 0.56 10.2 0.6 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3043) ODV-E18 PF10717.9 OQS04623.1 - 3 7.8 7.4 13 5.8 0.9 2.9 2 1 0 2 2 2 0 Occlusion-derived virus envelope protein ODV-E18 DUF2231 PF09990.9 OQS04623.1 - 3.2 8.2 14.4 0.91 10.0 10.2 2.0 2 0 0 2 2 2 0 Predicted membrane protein (DUF2231) DUF3810 PF12725.7 OQS04623.1 - 3.6 6.8 8.8 0.29 10.4 4.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3810) ABC2_membrane_2 PF12679.7 OQS04623.1 - 4.4 6.5 17.4 9.2 5.4 17.4 1.7 1 1 0 1 1 1 0 ABC-2 family transporter protein FA_desaturase PF00487.24 OQS04623.1 - 7.6 6.3 6.2 14 5.4 6.2 1.4 1 0 0 1 1 1 0 Fatty acid desaturase Tetraspanin PF00335.20 OQS04624.1 - 2.1e-15 57.1 19.3 4.2e-15 56.1 19.3 1.5 1 1 0 1 1 1 1 Tetraspanin family DUF3810 PF12725.7 OQS04624.1 - 0.016 14.6 1.1 0.026 13.9 1.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) DUF2569 PF10754.9 OQS04624.1 - 0.049 14.1 7.7 0.062 13.7 5.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2569) CpXC PF14353.6 OQS04624.1 - 0.085 12.9 0.3 0.14 12.2 0.3 1.3 1 0 0 1 1 1 0 CpXC protein WBP-1 PF11669.8 OQS04624.1 - 0.12 13.1 1.7 0.47 11.1 0.1 2.4 2 1 0 2 2 2 0 WW domain-binding protein 1 PPR PF01535.20 OQS04624.1 - 0.13 12.6 0.3 1.4 9.3 0.0 2.7 2 0 0 2 2 2 0 PPR repeat DUF2981 PF11200.8 OQS04624.1 - 0.14 11.9 7.5 0.31 10.7 7.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2981) DUF3043 PF11241.8 OQS04624.1 - 0.73 9.8 3.0 0.53 10.3 1.3 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3043) DUF373 PF04123.13 OQS04624.1 - 1.8 7.9 10.7 0.93 8.9 8.2 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF373) DUF4271 PF14093.6 OQS04624.1 - 3.7 7.4 15.2 0.93 9.4 11.7 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4271) zf-C2HC_2 PF13913.6 OQS04625.1 - 7.7e-11 41.6 13.2 2.7e-06 27.1 2.6 2.5 2 0 0 2 2 2 2 zinc-finger of a C2HC-type zf-CpG_bind_C PF12269.8 OQS04625.1 - 0.00016 21.5 0.3 0.00016 21.5 0.3 2.2 1 1 1 2 2 2 1 CpG binding protein zinc finger C terminal domain FYVE PF01363.21 OQS04625.1 - 0.027 14.6 0.1 0.027 14.6 0.1 2.9 3 0 0 3 3 3 0 FYVE zinc finger zf-C2H2 PF00096.26 OQS04625.1 - 0.15 12.6 0.2 0.15 12.6 0.2 4.0 3 1 1 4 4 4 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 OQS04625.1 - 0.34 11.9 15.3 1.9 9.5 0.5 4.0 3 1 1 4 4 4 0 C2H2-type zinc finger HypA PF01155.19 OQS04625.1 - 0.56 10.2 4.5 3.2 7.8 0.0 2.8 3 0 0 3 3 3 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-LYAR PF08790.11 OQS04625.1 - 2.3 8.2 7.3 0.75 9.8 0.5 2.9 3 0 0 3 3 3 0 LYAR-type C2HC zinc finger Peptidase_S28 PF05577.12 OQS04626.1 - 6.4e-79 265.8 0.0 9e-79 265.3 0.0 1.2 1 0 0 1 1 1 1 Serine carboxypeptidase S28 Peptidase_S37 PF05576.11 OQS04626.1 - 9.3e-11 41.0 0.0 1.4e-10 40.5 0.0 1.2 1 0 0 1 1 1 1 PS-10 peptidase S37 Hydrolase_4 PF12146.8 OQS04626.1 - 3.9e-06 26.3 0.0 5.8e-06 25.7 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 OQS04626.1 - 0.00041 19.9 0.3 0.0013 18.3 0.0 1.8 2 0 0 2 2 2 1 Prolyl oligopeptidase family DUF2920 PF11144.8 OQS04626.1 - 0.0026 17.0 0.0 0.0039 16.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2920) Abhydrolase_1 PF00561.20 OQS04626.1 - 0.0074 16.0 0.0 0.02 14.5 0.0 1.7 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 OQS04626.1 - 0.017 15.7 1.0 0.038 14.6 1.0 1.8 1 1 0 1 1 1 0 Alpha/beta hydrolase family zf-C3HC PF07967.13 OQS04627.1 - 3e-29 101.7 8.4 5.3e-23 81.5 2.0 2.2 2 0 0 2 2 2 2 C3HC zinc finger-like Rsm1 PF08600.10 OQS04627.1 - 4.3e-08 33.2 10.9 8.4e-07 29.1 1.3 2.6 2 0 0 2 2 2 2 Rsm1-like BIR PF00653.21 OQS04627.1 - 0.00011 22.7 1.0 0.27 11.9 0.4 2.7 2 0 0 2 2 2 2 Inhibitor of Apoptosis domain E1-E2_ATPase PF00122.20 OQS04628.1 - 9.2e-46 155.6 3.5 9.2e-46 155.6 3.5 1.9 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 OQS04628.1 - 8.7e-44 150.3 0.0 1.9e-43 149.2 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HMA PF00403.26 OQS04628.1 - 9e-32 109.3 14.7 3.3e-12 46.7 0.4 4.0 4 0 0 4 4 4 3 Heavy-metal-associated domain Hydrolase_3 PF08282.12 OQS04628.1 - 4.5e-06 26.6 2.6 0.004 16.9 1.1 3.0 2 1 1 3 3 3 2 haloacid dehalogenase-like hydrolase NapD PF03927.13 OQS04628.1 - 0.0004 20.4 1.3 1.1 9.4 0.0 3.0 3 0 0 3 3 3 2 NapD protein HAD PF12710.7 OQS04628.1 - 0.005 17.3 0.0 0.01 16.2 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase DAHP_synth_2 PF01474.16 OQS04629.1 - 5.1e-191 634.9 0.0 6.4e-191 634.6 0.0 1.1 1 0 0 1 1 1 1 Class-II DAHP synthetase family DUF4604 PF15377.6 OQS04629.1 - 0.039 14.4 13.0 0.065 13.7 13.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4604) SPRY PF00622.28 OQS04630.1 - 0.0051 16.9 0.0 0.015 15.5 0.0 1.8 1 0 0 1 1 1 1 SPRY domain DUF5492 PF17596.2 OQS04630.1 - 0.11 12.9 0.2 0.11 12.9 0.2 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5492) ABC_membrane PF00664.23 OQS04632.1 - 1e-63 215.6 4.3 1.3e-63 215.2 4.3 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 OQS04632.1 - 1.3e-12 48.4 0.1 2.4e-12 47.6 0.1 1.4 1 0 0 1 1 1 1 ABC transporter AAA_29 PF13555.6 OQS04632.1 - 0.0007 19.3 0.1 0.0015 18.3 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 OQS04632.1 - 0.0057 16.6 0.1 0.011 15.7 0.1 1.4 1 0 0 1 1 1 1 RsgA GTPase DUF87 PF01935.17 OQS04632.1 - 0.0086 16.2 0.1 0.016 15.3 0.1 1.3 1 0 0 1 1 1 1 Helicase HerA, central domain AAA_16 PF13191.6 OQS04632.1 - 0.017 15.5 0.2 0.034 14.5 0.2 1.4 1 0 0 1 1 1 0 AAA ATPase domain G-alpha PF00503.20 OQS04632.1 - 0.034 13.3 0.0 0.052 12.7 0.0 1.2 1 0 0 1 1 1 0 G-protein alpha subunit AAA_30 PF13604.6 OQS04632.1 - 0.052 13.3 0.1 0.25 11.1 0.0 2.1 2 0 0 2 2 2 0 AAA domain UPF0114 PF03350.16 OQS04632.1 - 0.067 13.4 0.1 0.2 11.9 0.1 1.9 1 1 0 1 1 1 0 Uncharacterized protein family, UPF0114 AAA_25 PF13481.6 OQS04632.1 - 0.12 11.9 0.0 0.22 11.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 OQS04632.1 - 0.14 11.7 0.4 0.36 10.3 0.0 1.7 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_22 PF13401.6 OQS04632.1 - 0.15 12.4 0.1 0.35 11.1 0.1 1.6 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 OQS04632.1 - 0.17 12.0 0.0 0.46 10.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 OQS04632.1 - 0.18 11.1 0.0 0.29 10.4 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin Suppressor_APC PF11414.8 OQS04633.1 - 0.029 14.4 8.5 0.46 10.6 2.0 3.2 1 1 1 2 2 2 0 Adenomatous polyposis coli tumour suppressor protein DUF421 PF04239.12 OQS04633.1 - 0.031 14.0 1.8 0.071 12.9 1.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF421) UPF0242 PF06785.11 OQS04633.1 - 0.11 12.6 17.0 0.021 14.9 13.0 2.0 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus PI3K_P85_iSH2 PF16454.5 OQS04633.1 - 1.1 8.8 17.9 1.6 8.3 6.5 2.7 1 1 1 2 2 2 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain FapA PF03961.13 OQS04633.1 - 5.1 5.6 9.9 8.5 4.9 9.9 1.3 1 0 0 1 1 1 0 Flagellar Assembly Protein A DUF1664 PF07889.12 OQS04633.1 - 5.8 7.0 10.5 29 4.7 5.9 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) DUF4407 PF14362.6 OQS04633.1 - 10 5.4 10.4 0.99 8.7 5.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) FMN_dh PF01070.18 OQS04634.1 - 1.8e-265 879.0 0.2 4.7e-132 440.2 0.0 2.0 2 0 0 2 2 2 2 FMN-dependent dehydrogenase IMPDH PF00478.25 OQS04634.1 - 2.2e-10 40.1 2.4 0.00023 20.3 0.2 2.8 2 1 0 2 2 2 2 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.17 OQS04634.1 - 9.6e-09 34.8 0.8 0.0033 16.6 0.1 2.2 2 0 0 2 2 2 2 Conserved region in glutamate synthase ThiG PF05690.14 OQS04634.1 - 5.6e-07 29.1 5.4 0.14 11.5 0.1 4.2 2 2 2 4 4 4 2 Thiazole biosynthesis protein ThiG His_biosynth PF00977.21 OQS04634.1 - 0.0001 21.9 0.1 0.28 10.6 0.0 2.5 2 0 0 2 2 2 2 Histidine biosynthesis protein DUF1031 PF06275.11 OQS04634.1 - 0.00026 21.2 0.0 0.8 10.0 0.0 2.8 2 0 0 2 2 2 2 Protein of unknown function (DUF1031) G3P_antiterm PF04309.12 OQS04634.1 - 0.00078 18.9 0.0 1.3 8.4 0.0 3.1 2 2 1 3 3 3 2 Glycerol-3-phosphate responsive antiterminator PSI_PSAK PF01241.18 OQS04634.1 - 0.0022 18.0 0.1 1.8 8.6 0.0 2.5 2 0 0 2 2 2 2 Photosystem I psaG / psaK TMP-TENI PF02581.17 OQS04634.1 - 0.0046 16.3 0.0 0.83 9.0 0.0 2.6 2 0 0 2 2 2 1 Thiamine monophosphate synthase NMO PF03060.15 OQS04634.1 - 0.15 11.4 4.5 1.7 7.9 0.4 2.2 2 0 0 2 2 2 0 Nitronate monooxygenase DHO_dh PF01180.21 OQS04634.1 - 0.17 11.0 0.0 12 5.0 0.0 2.5 2 0 0 2 2 2 0 Dihydroorotate dehydrogenase Maf_N PF08383.11 OQS04634.1 - 0.18 11.6 0.1 23 4.8 0.0 2.7 2 0 0 2 2 2 0 Maf N-terminal region Cpn60_TCP1 PF00118.24 OQS04635.1 - 2.2e-156 521.3 7.1 2.5e-156 521.2 7.1 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family ISN1 PF06437.11 OQS04635.1 - 0.041 12.8 0.1 0.069 12.0 0.1 1.3 1 0 0 1 1 1 0 IMP-specific 5'-nucleotidase PDZ PF00595.24 OQS04636.1 - 1.8e-11 44.2 0.2 0.00022 21.5 0.1 2.8 2 0 0 2 2 2 2 PDZ domain PDZ_6 PF17820.1 OQS04636.1 - 2.1e-11 43.5 0.0 1.6e-05 24.7 0.0 2.6 2 0 0 2 2 2 2 PDZ domain PDZ_2 PF13180.6 OQS04636.1 - 3.9e-06 27.1 0.1 0.00044 20.5 0.0 2.5 2 0 0 2 2 2 1 PDZ domain CO_dh PF02552.16 OQS04636.1 - 0.02 14.7 0.8 0.6 9.9 0.1 2.4 2 0 0 2 2 2 0 CO dehydrogenase beta subunit/acetyl-CoA synthase epsilon subunit Tiam_CC_Ex PF18385.1 OQS04636.1 - 0.079 13.4 3.5 10 6.6 0.1 2.9 2 0 0 2 2 2 0 T-lymphoma invasion and metastasis CC-Ex domain DUF365 PF04033.12 OQS04636.1 - 0.75 10.1 5.2 8.8 6.7 0.3 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF365) Lyase_catalyt PF09093.11 OQS04636.1 - 1.4 8.0 12.4 1.5 7.8 1.2 2.8 4 0 0 4 4 4 0 Lyase, catalytic DUF1043 PF06295.12 OQS04636.1 - 1.7 8.6 6.3 7.6 6.6 0.6 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1043) DB_JBP1 PF18526.1 OQS04637.1 - 0.087 12.8 0.2 0.36 10.8 0.0 1.8 2 0 0 2 2 2 0 Thymine dioxygenase JBP1 DNA-binding domain ASH PF15780.5 OQS04639.1 - 2.1e-10 40.7 13.3 0.79 10.0 0.0 9.2 10 0 0 10 10 10 4 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin PapD-like PF14874.6 OQS04639.1 - 7.7e-10 38.9 3.2 0.004 17.3 0.1 5.1 5 0 0 5 5 5 3 Flagellar-associated PapD-like Motile_Sperm PF00635.26 OQS04639.1 - 2.3e-07 30.6 0.4 0.29 11.0 0.0 6.5 7 0 0 7 7 7 2 MSP (Major sperm protein) domain fn3_5 PF06280.12 OQS04639.1 - 0.0066 17.1 2.0 5 7.8 0.1 4.0 4 0 0 4 4 4 2 Fn3-like domain TMEM131_like PF12371.8 OQS04639.1 - 0.066 13.5 2.0 20 5.5 0.1 4.1 4 1 0 4 4 4 0 Transmembrane protein 131-like LRR_8 PF13855.6 OQS04640.1 - 0.00013 21.6 0.5 0.00013 21.6 0.5 2.6 2 1 0 2 2 2 1 Leucine rich repeat Amidinotransf PF02274.17 OQS04641.1 - 7.9e-12 44.9 0.0 5.1e-09 35.7 0.0 3.5 3 1 0 3 3 3 2 Amidinotransferase PAD_porph PF04371.15 OQS04641.1 - 0.013 14.8 0.0 0.019 14.2 0.0 1.3 1 0 0 1 1 1 0 Porphyromonas-type peptidyl-arginine deiminase GARS_A PF01071.19 OQS04642.1 - 1.8e-76 256.3 0.1 3e-76 255.5 0.1 1.4 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain Formyl_trans_N PF00551.19 OQS04642.1 - 1.4e-40 139.0 0.0 2.4e-40 138.2 0.0 1.4 1 0 0 1 1 1 1 Formyl transferase GARS_N PF02844.15 OQS04642.1 - 1e-34 119.1 1.6 6.9e-34 116.5 0.1 2.8 3 0 0 3 3 2 1 Phosphoribosylglycinamide synthetase, N domain GARS_C PF02843.16 OQS04642.1 - 1.1e-31 108.9 0.6 3.5e-31 107.3 0.6 2.0 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, C domain AIRS_C PF02769.22 OQS04642.1 - 1.3e-31 109.8 0.1 5e-31 107.9 0.0 2.1 2 0 0 2 2 2 1 AIR synthase related protein, C-terminal domain AIRS PF00586.24 OQS04642.1 - 3.8e-15 56.3 5.3 2.2e-14 53.9 2.1 2.9 2 0 0 2 2 2 1 AIR synthase related protein, N-terminal domain CPSase_L_D2 PF02786.17 OQS04642.1 - 7.8e-06 25.5 0.1 1.6e-05 24.5 0.1 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain ATP-grasp PF02222.22 OQS04642.1 - 9.1e-06 25.4 0.0 1.7e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.14 OQS04642.1 - 3.9e-05 23.7 0.0 8.6e-05 22.6 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain AICARFT_IMPCHas PF01808.18 OQS04642.1 - 0.00012 21.6 0.1 0.00028 20.4 0.1 1.6 1 0 0 1 1 1 1 AICARFT/IMPCHase bienzyme CoA_binding_2 PF13380.6 OQS04642.1 - 0.01 16.3 0.9 0.74 10.3 0.0 3.5 4 0 0 4 4 3 0 CoA binding domain RimK PF08443.11 OQS04642.1 - 0.032 13.8 0.0 0.074 12.6 0.0 1.6 1 0 0 1 1 1 0 RimK-like ATP-grasp domain ATP-grasp_4 PF13535.6 OQS04642.1 - 0.039 13.5 0.0 0.074 12.6 0.0 1.4 1 0 0 1 1 1 0 ATP-grasp domain ATPgrasp_ST PF14397.6 OQS04642.1 - 0.14 11.4 0.0 0.52 9.5 0.0 1.9 2 0 0 2 2 2 0 Sugar-transfer associated ATP-grasp CRAL_TRIO PF00650.20 OQS04643.1 - 7e-34 116.8 0.0 1.5e-33 115.7 0.0 1.6 1 0 0 1 1 1 1 CRAL/TRIO domain PH PF00169.29 OQS04643.1 - 0.0073 16.8 0.0 0.044 14.3 0.0 2.4 1 0 0 1 1 1 1 PH domain PH_8 PF15409.6 OQS04643.1 - 0.054 13.8 1.1 0.34 11.2 1.1 2.3 1 1 0 1 1 1 0 Pleckstrin homology domain Cytomega_UL84 PF06284.11 OQS04643.1 - 0.071 11.6 5.7 0.11 10.9 5.7 1.2 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein CRAL_TRIO_2 PF13716.6 OQS04643.1 - 0.13 12.4 0.0 0.39 10.9 0.0 1.8 1 0 0 1 1 1 0 Divergent CRAL/TRIO domain AAA_13 PF13166.6 OQS04643.1 - 2.7 6.5 16.1 3.9 6.0 16.1 1.1 1 0 0 1 1 1 0 AAA domain DUF4011 PF13195.6 OQS04643.1 - 6.2 6.7 13.1 13 5.7 13.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4011) N_BRCA1_IG PF16158.5 OQS04644.1 - 6.7e-15 55.7 0.0 1.1e-14 55.0 0.0 1.4 1 0 0 1 1 1 1 Ig-like domain from next to BRCA1 gene UBA_4 PF14555.6 OQS04644.1 - 1.4e-11 44.0 3.3 2.3e-09 36.9 3.3 2.4 1 1 0 1 1 1 1 UBA-like domain TAP_C PF03943.13 OQS04644.1 - 0.0043 16.7 0.2 0.008 15.8 0.2 1.4 1 0 0 1 1 1 1 TAP C-terminal domain CUE PF02845.16 OQS04644.1 - 0.073 12.8 0.0 0.17 11.6 0.0 1.6 1 0 0 1 1 1 0 CUE domain CARDB PF07705.11 OQS04644.1 - 0.093 13.0 0.0 0.16 12.2 0.0 1.4 1 0 0 1 1 1 0 CARDB Transmemb_17 PF09799.9 OQS04645.1 - 1.8e-22 80.0 11.6 2.1e-22 79.7 11.6 1.1 1 0 0 1 1 1 1 Predicted membrane protein Aa_trans PF01490.18 OQS04646.1 - 1.1e-12 47.5 31.3 6.9e-12 44.8 31.3 2.0 1 1 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 OQS04646.1 - 0.021 13.9 23.3 0.043 12.9 22.7 1.7 1 1 0 1 1 1 0 Tryptophan/tyrosine permease family Toxin_4 PF00706.17 OQS04646.1 - 0.13 12.7 1.7 0.39 11.2 1.7 1.8 1 0 0 1 1 1 0 Anenome neurotoxin SF3A2 PF16835.5 OQS04647.1 - 6.1e-35 119.5 0.0 9.4e-35 118.9 0.0 1.3 1 0 0 1 1 1 1 Pre-mRNA-splicing factor SF3a complex subunit 2 (Prp11) ubiquitin PF00240.23 OQS04647.1 - 2.6e-09 36.7 0.0 5.1e-09 35.8 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family zf-met PF12874.7 OQS04647.1 - 1.7e-06 28.2 1.1 3.7e-06 27.1 1.1 1.6 1 0 0 1 1 1 1 Zinc-finger of C2H2 type CactinC_cactus PF09732.9 OQS04647.1 - 2.9e-05 24.0 0.4 4.5e-05 23.4 0.4 1.3 1 0 0 1 1 1 1 Cactus-binding C-terminus of cactin protein Rad60-SLD PF11976.8 OQS04647.1 - 3.7e-05 23.5 0.1 0.00011 22.0 0.0 1.9 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like Bac_rhamnosid_C PF17390.2 OQS04647.1 - 0.17 11.7 0.0 0.43 10.4 0.0 1.7 1 0 0 1 1 1 0 Bacterial alpha-L-rhamnosidase C-terminal domain Ubiquitin_4 PF18036.1 OQS04647.1 - 0.18 11.9 0.1 23 5.1 0.0 2.4 2 0 0 2 2 2 0 Ubiquitin-like domain ThiF PF00899.21 OQS04648.1 - 1.4e-57 194.9 0.1 2.8e-57 193.9 0.1 1.5 1 1 0 1 1 1 1 ThiF family Rhodanese PF00581.20 OQS04648.1 - 5.7e-12 46.1 0.0 1.1e-11 45.1 0.0 1.5 1 0 0 1 1 1 1 Rhodanese-like domain UAA PF08449.11 OQS04649.1 - 2e-45 155.3 18.1 2.7e-45 154.9 18.1 1.1 1 0 0 1 1 1 1 UAA transporter family Myb_DNA-binding PF00249.31 OQS04649.1 - 1.6e-11 44.2 0.5 2.7e-11 43.5 0.5 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OQS04649.1 - 0.0013 18.6 0.8 0.0029 17.5 0.8 1.5 1 0 0 1 1 1 1 Myb DNA-binding like Myb_DNA-bind_6 PF13921.6 OQS04649.1 - 0.0016 18.6 0.1 0.0035 17.6 0.1 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain TPT PF03151.16 OQS04649.1 - 0.0053 16.2 3.2 0.0053 16.2 3.2 2.1 2 0 0 2 2 2 1 Triose-phosphate Transporter family EamA PF00892.20 OQS04649.1 - 0.009 16.2 24.3 0.31 11.2 12.2 3.0 2 1 1 3 3 3 2 EamA-like transporter family CPP1-like PF11833.8 OQS04649.1 - 0.17 11.5 1.2 16 5.0 0.4 2.6 2 0 0 2 2 2 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like PHD PF00628.29 OQS04650.1 - 8.8e-09 35.1 4.6 1.8e-08 34.1 4.6 1.5 1 0 0 1 1 1 1 PHD-finger SnAC PF14619.6 OQS04650.1 - 0.02 15.5 2.7 7.5 7.2 0.4 3.9 3 0 0 3 3 3 0 Snf2-ATP coupling, chromatin remodelling complex FANCL_C PF11793.8 OQS04650.1 - 0.088 13.0 1.6 0.17 12.1 1.6 1.4 1 0 0 1 1 1 0 FANCL C-terminal domain Prok-RING_1 PF14446.6 OQS04650.1 - 0.12 12.3 1.8 0.26 11.3 1.8 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 C1_2 PF03107.16 OQS04650.1 - 0.4 11.0 2.4 0.42 11.0 0.5 1.9 2 0 0 2 2 2 0 C1 domain zf-RING_2 PF13639.6 OQS04650.1 - 0.56 10.6 5.6 0.98 9.8 5.6 1.4 1 0 0 1 1 1 0 Ring finger domain zf-PHD-like PF15446.6 OQS04650.1 - 0.96 9.1 4.5 0.68 9.5 2.1 2.1 2 0 0 2 2 2 0 PHD/FYVE-zinc-finger like domain Zf_RING PF16744.5 OQS04650.1 - 3 8.0 5.2 7.5 6.7 5.2 1.7 1 1 0 1 1 1 0 KIAA1045 RING finger cNMP_binding PF00027.29 OQS04651.1 - 1.8e-17 63.2 0.2 6.1e-07 29.4 0.0 3.5 3 0 0 3 3 3 3 Cyclic nucleotide-binding domain zf-CCHC_5 PF14787.6 OQS04651.1 - 0.0097 15.6 0.2 0.023 14.4 0.2 1.7 1 0 0 1 1 1 1 GAG-polyprotein viral zinc-finger Kri1_C PF12936.7 OQS04652.1 - 2e-25 88.8 3.5 2e-25 88.8 3.5 5.0 4 1 1 5 5 5 1 KRI1-like family C-terminal Kri1 PF05178.12 OQS04652.1 - 1.6e-21 76.8 8.1 1.6e-21 76.8 8.1 6.9 4 4 1 6 6 6 1 KRI1-like family GDPD PF03009.17 OQS04653.1 - 3.1e-09 36.9 0.0 3.1e-09 36.9 0.0 2.6 3 0 0 3 3 3 1 Glycerophosphoryl diester phosphodiesterase family XRN1_DBM PF18245.1 OQS04653.1 - 1.4 9.0 3.8 1.3 9.1 1.3 2.2 2 0 0 2 2 2 0 5-3 exonuclease XRN1 DCP1-binding motif Cep57_CLD_2 PF14197.6 OQS04654.1 - 0.0001 22.3 0.7 0.0001 22.3 0.7 9.4 6 4 2 8 8 8 1 Centrosome localisation domain of PPC89 ADIP PF11559.8 OQS04654.1 - 0.013 15.6 15.9 0.013 15.6 15.9 9.0 3 2 6 10 10 10 0 Afadin- and alpha -actinin-Binding ATP-synt_F6 PF05511.11 OQS04654.1 - 0.013 15.9 2.1 0.09 13.2 0.2 3.0 2 0 0 2 2 2 0 Mitochondrial ATP synthase coupling factor 6 GAF PF01590.26 OQS04655.1 - 0.00012 22.7 0.0 0.00033 21.3 0.0 1.7 1 0 0 1 1 1 1 GAF domain GAF_2 PF13185.6 OQS04655.1 - 0.0016 18.8 0.0 0.0054 17.0 0.0 1.8 2 0 0 2 2 2 1 GAF domain DUF3464 PF11947.8 OQS04655.1 - 0.28 10.9 1.2 3.2 7.5 0.0 2.4 2 0 0 2 2 2 0 Photosynthesis affected mutant 68 AAA_12 PF13087.6 OQS04656.1 - 3.7e-51 173.6 0.1 6.3e-51 172.8 0.1 1.4 1 0 0 1 1 1 1 AAA domain Dna2 PF08696.11 OQS04656.1 - 3.8e-40 137.9 0.0 8.2e-40 136.8 0.0 1.5 1 0 0 1 1 1 1 DNA replication factor Dna2 AAA_11 PF13086.6 OQS04656.1 - 2.6e-26 93.0 5.4 1.5e-14 54.4 0.1 2.9 2 1 1 3 3 3 2 AAA domain AAA_30 PF13604.6 OQS04656.1 - 1.1e-12 48.1 0.0 2.5e-12 46.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 OQS04656.1 - 9.1e-11 42.3 0.1 2.5e-10 40.9 0.1 1.8 1 0 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 OQS04656.1 - 2e-06 27.8 0.5 0.3 10.8 0.0 3.4 2 1 1 3 3 3 3 Viral (Superfamily 1) RNA helicase PDDEXK_1 PF12705.7 OQS04656.1 - 4.1e-06 26.9 0.0 8.1e-06 25.9 0.0 1.5 1 0 0 1 1 1 1 PD-(D/E)XK nuclease superfamily Helicase_RecD PF05127.14 OQS04656.1 - 4.4e-05 23.4 0.0 0.00015 21.7 0.0 2.0 1 0 0 1 1 1 1 Helicase Cas_Cas4 PF01930.17 OQS04656.1 - 0.00029 21.0 0.1 0.00097 19.3 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function DUF83 UvrD-helicase PF00580.21 OQS04656.1 - 0.017 14.7 0.4 0.31 10.5 0.0 2.8 2 1 1 3 3 3 0 UvrD/REP helicase N-terminal domain AAA_16 PF13191.6 OQS04656.1 - 0.052 13.9 0.0 0.63 10.4 0.0 2.8 2 0 0 2 2 2 0 AAA ATPase domain U3_assoc_6 PF08640.11 OQS04656.1 - 0.16 12.1 0.0 0.48 10.5 0.0 1.7 1 0 0 1 1 1 0 U3 small nucleolar RNA-associated protein 6 UvrD_C_2 PF13538.6 OQS04656.1 - 0.19 11.6 0.0 0.42 10.5 0.0 1.6 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain ANAPC4_WD40 PF12894.7 OQS04657.1 - 3.7e-10 40.0 0.0 0.27 11.6 0.0 4.4 3 1 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 OQS04657.1 - 1.9e-09 38.0 3.1 0.00026 21.7 0.0 5.9 6 0 0 6 6 6 1 WD domain, G-beta repeat Mcl1_mid PF12341.8 OQS04657.1 - 0.016 14.5 0.0 0.029 13.7 0.0 1.5 1 0 0 1 1 1 0 Minichromosome loss protein, Mcl1, middle region YabA PF06156.13 OQS04657.1 - 0.018 15.7 1.8 0.018 15.7 1.8 1.9 1 1 1 2 2 2 0 Initiation control protein YabA DUF1462 PF07315.11 OQS04657.1 - 0.095 13.0 0.1 0.19 12.0 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1462) DUF1664 PF07889.12 OQS04657.1 - 0.16 12.0 1.8 0.29 11.2 1.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) WD40_like PF17005.5 OQS04657.1 - 0.17 11.2 0.0 2.9 7.1 0.1 2.2 1 1 0 2 2 2 0 WD40-like domain PAC1 PF16094.5 OQS04658.1 - 2e-07 30.5 0.0 2.8e-07 30.0 0.0 1.3 1 1 0 1 1 1 1 Proteasome assembly chaperone 4 HEAT_2 PF13646.6 OQS04662.1 - 3.3e-06 27.4 0.7 0.37 11.2 0.1 4.7 4 0 0 4 4 4 2 HEAT repeats Arm PF00514.23 OQS04662.1 - 3.4e-05 23.7 15.1 0.59 10.3 0.3 7.3 7 0 0 7 7 7 3 Armadillo/beta-catenin-like repeat WW PF00397.26 OQS04662.1 - 7.7e-05 22.7 1.1 0.00026 21.0 1.1 1.9 1 0 0 1 1 1 1 WW domain Atx10homo_assoc PF09759.9 OQS04662.1 - 0.00031 20.7 11.5 0.001 19.0 0.2 4.3 4 0 0 4 4 4 2 Spinocerebellar ataxia type 10 protein domain Ras PF00071.22 OQS04664.1 - 2.6e-41 140.9 0.0 3.8e-41 140.4 0.0 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OQS04664.1 - 6e-33 113.6 0.0 1e-32 112.9 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase NT-C2 PF10358.9 OQS04664.1 - 1.2e-16 60.7 0.0 2.8e-16 59.6 0.0 1.6 1 0 0 1 1 1 1 N-terminal C2 in EEIG1 and EHBP1 proteins Arf PF00025.21 OQS04664.1 - 8.4e-08 31.9 0.1 2.7e-07 30.2 0.0 1.8 2 0 0 2 2 2 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 OQS04664.1 - 6.4e-06 25.7 0.9 1.9e-05 24.2 0.0 1.9 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 OQS04664.1 - 0.00057 19.9 0.0 0.0026 17.8 0.0 2.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 OQS04664.1 - 0.044 13.3 0.0 0.2 11.2 0.0 2.0 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain MMR_HSR1_Xtn PF16897.5 OQS04664.1 - 0.045 13.8 0.1 0.14 12.2 0.0 1.9 2 0 0 2 2 2 0 C-terminal region of MMR_HSR1 domain YwhD PF08741.10 OQS04664.1 - 0.11 12.2 0.0 0.26 11.0 0.0 1.6 1 0 0 1 1 1 0 YwhD family Methyltransf_25 PF13649.6 OQS04665.1 - 1.1e-12 48.5 0.0 2e-12 47.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OQS04665.1 - 6.4e-12 46.0 0.0 1.7e-11 44.6 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 OQS04665.1 - 8.8e-11 42.4 0.0 1.4e-10 41.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OQS04665.1 - 8.7e-10 38.6 0.0 1.8e-09 37.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 OQS04665.1 - 1e-09 38.1 0.0 1.5e-09 37.5 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 OQS04665.1 - 3.1e-08 33.6 0.0 5.1e-08 32.9 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 OQS04665.1 - 0.0023 17.7 0.0 0.0034 17.2 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_24 PF13578.6 OQS04665.1 - 0.0072 17.3 0.0 0.017 16.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltr_RsmB-F PF01189.17 OQS04665.1 - 0.03 14.0 0.0 0.13 11.9 0.0 1.8 2 0 0 2 2 2 0 16S rRNA methyltransferase RsmB/F Methyltransf_3 PF01596.17 OQS04665.1 - 0.078 12.1 0.0 0.12 11.6 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase Methyltransf_28 PF02636.17 OQS04665.1 - 0.14 11.8 0.0 0.23 11.0 0.0 1.3 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase ABC2_membrane PF01061.24 OQS04666.1 - 6.4e-40 136.8 25.5 8.8e-40 136.4 25.5 1.2 1 0 0 1 1 1 1 ABC-2 type transporter ABC2_membrane_3 PF12698.7 OQS04666.1 - 6.1e-09 35.5 16.3 9e-09 34.9 16.3 1.3 1 0 0 1 1 1 1 ABC-2 family transporter protein ABC_tran PF00005.27 OQS04666.1 - 8.1e-08 32.9 0.0 1.6e-07 31.9 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 OQS04666.1 - 2.3e-05 24.3 0.0 8.3e-05 22.5 0.0 1.8 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system Mtc PF03820.17 OQS04667.1 - 9e-93 310.7 0.9 1.1e-92 310.5 0.9 1.0 1 0 0 1 1 1 1 Tricarboxylate carrier COPI_assoc PF08507.10 OQS04668.1 - 7e-13 48.8 8.2 8.9e-13 48.4 8.2 1.2 1 0 0 1 1 1 1 COPI associated protein Pox_P35 PF03213.14 OQS04668.1 - 0.0068 15.7 0.5 0.011 15.0 0.5 1.3 1 0 0 1 1 1 1 Poxvirus P35 protein S_4TM PF18159.1 OQS04668.1 - 0.75 9.0 2.3 1.1 8.5 2.3 1.2 1 0 0 1 1 1 0 SMODS-associating 4TM effector domain ARL2_Bind_BART PF11527.8 OQS04669.1 - 8.3e-14 51.7 5.3 9.4e-14 51.5 5.3 1.0 1 0 0 1 1 1 1 The ARF-like 2 binding protein BART putAbiC PF16872.5 OQS04669.1 - 0.22 12.2 3.4 12 6.7 0.1 2.6 2 1 0 2 2 2 0 Putative phage abortive infection protein Pkinase PF00069.25 OQS04670.1 - 2.2e-63 214.1 0.0 2.9e-63 213.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQS04670.1 - 8.1e-34 117.1 0.0 1.1e-33 116.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase DEP PF00610.21 OQS04670.1 - 5.5e-09 36.0 0.0 1.6e-08 34.4 0.0 1.9 2 0 0 2 2 2 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Kinase-like PF14531.6 OQS04670.1 - 2e-08 33.9 0.0 6e-08 32.3 0.0 1.8 2 0 0 2 2 2 1 Kinase-like FTA2 PF13095.6 OQS04670.1 - 0.00019 21.2 0.0 0.26 10.9 0.0 2.7 3 0 0 3 3 3 2 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 OQS04670.1 - 0.0081 16.1 0.4 0.026 14.4 0.0 2.1 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 OQS04670.1 - 0.043 13.2 0.3 0.11 11.9 0.1 1.7 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 OQS04670.1 - 0.079 11.9 0.0 0.13 11.2 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Put_Phosphatase PF06888.12 OQS04671.1 - 6.9e-50 169.6 0.0 1.6e-49 168.5 0.0 1.5 1 1 0 1 1 1 1 Putative Phosphatase zf-CCCH PF00642.24 OQS04671.1 - 1.3e-16 60.1 18.3 6.2e-11 41.9 4.8 2.5 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) BT1 PF03092.16 OQS04671.1 - 1.6e-09 36.6 1.9 1.6e-09 36.6 1.9 2.5 2 1 0 2 2 2 1 BT1 family zf_CCCH_4 PF18345.1 OQS04671.1 - 1.2e-08 34.7 17.5 0.00011 22.2 6.3 2.6 2 0 0 2 2 2 2 Zinc finger domain HAD PF12710.7 OQS04671.1 - 2.9e-08 34.4 0.0 1e-07 32.5 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase PUCC PF03209.15 OQS04671.1 - 0.00017 20.7 1.6 0.00017 20.7 1.6 2.7 1 1 0 2 2 2 1 PUCC protein zf-CCCH_4 PF18044.1 OQS04671.1 - 0.00052 19.8 25.8 0.00087 19.0 2.9 2.7 3 0 0 3 3 3 2 CCCH-type zinc finger Torus PF16131.5 OQS04671.1 - 0.004 17.8 9.3 0.067 13.9 1.0 2.5 1 1 1 2 2 2 2 Torus domain zf-CCCH_2 PF14608.6 OQS04671.1 - 0.013 16.0 10.0 0.18 12.3 1.1 2.7 2 0 0 2 2 2 0 RNA-binding, Nab2-type zinc finger MPS2 PF17060.5 OQS04671.1 - 0.17 11.1 0.1 0.26 10.5 0.1 1.2 1 0 0 1 1 1 0 Monopolar spindle protein 2 LRR_8 PF13855.6 OQS04672.1 - 1e-41 140.5 62.2 6.6e-10 38.6 1.5 10.2 4 2 8 12 12 12 11 Leucine rich repeat LRR_4 PF12799.7 OQS04672.1 - 3.7e-31 106.7 68.1 0.00014 22.2 1.0 11.7 4 3 11 16 16 16 14 Leucine Rich repeats (2 copies) RRM_1 PF00076.22 OQS04672.1 - 8.2e-23 80.0 0.6 2e-08 33.9 0.0 4.8 3 1 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) LRR_9 PF14580.6 OQS04672.1 - 1.5e-10 40.8 26.1 0.00021 20.9 4.5 5.7 2 2 4 6 6 6 5 Leucine-rich repeat LRR_1 PF00560.33 OQS04672.1 - 2.1e-09 36.6 41.8 1.8 9.4 0.1 14.8 16 0 0 16 16 16 4 Leucine Rich Repeat RRM_occluded PF16842.5 OQS04672.1 - 0.00075 19.3 0.1 2.2 8.2 0.0 3.1 2 0 0 2 2 2 2 Occluded RNA-recognition motif RRM_Rrp7 PF17799.1 OQS04672.1 - 0.0058 16.4 0.1 0.28 11.0 0.0 3.0 3 0 0 3 3 3 1 Rrp7 RRM-like N-terminal domain RRM_7 PF16367.5 OQS04672.1 - 0.015 15.4 0.4 1.3 9.2 0.1 3.2 1 1 1 2 2 2 0 RNA recognition motif LRR_6 PF13516.6 OQS04672.1 - 1.1 9.5 50.2 0.82 9.9 0.9 12.4 12 0 0 12 12 12 0 Leucine Rich repeat AMP-binding PF00501.28 OQS04673.1 - 1.3e-42 145.9 0.0 1.8e-42 145.4 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme ACAS_N PF16177.5 OQS04673.1 - 9.3e-11 41.5 0.5 1.2e-09 37.9 0.5 2.3 2 0 0 2 2 2 1 Acetyl-coenzyme A synthetase N-terminus AMP-binding_C PF13193.6 OQS04673.1 - 0.002 19.0 0.1 0.0046 17.9 0.1 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain RRM_1 PF00076.22 OQS04674.1 - 2e-29 101.2 0.0 3.2e-17 62.1 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 OQS04674.1 - 0.0063 16.6 0.0 0.014 15.5 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif RRM_occluded PF16842.5 OQS04674.1 - 0.0063 16.3 0.0 1.9 8.4 0.0 2.3 2 0 0 2 2 2 2 Occluded RNA-recognition motif Nup35_RRM_2 PF14605.6 OQS04674.1 - 0.027 14.5 0.0 0.42 10.7 0.0 2.2 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.11 OQS04674.1 - 0.12 12.5 0.0 1.3 9.1 0.0 2.1 2 0 0 2 2 2 0 RNA binding motif PAP1 PF08601.10 OQS04674.1 - 0.75 9.5 11.2 0.89 9.2 11.2 1.1 1 0 0 1 1 1 0 Transcription factor PAP1 RSRP PF17069.5 OQS04674.1 - 1.6 8.3 44.7 2.2 7.8 44.7 1.1 1 0 0 1 1 1 0 Arginine/Serine-Rich protein 1 DUF4614 PF15391.6 OQS04674.1 - 3.6 7.6 19.6 4.7 7.2 19.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) LRR_6 PF13516.6 OQS04675.1 - 4.7e-10 38.7 12.2 6.4e-05 22.7 0.2 5.9 6 0 0 6 6 6 3 Leucine Rich repeat LRR_4 PF12799.7 OQS04675.1 - 4.1e-07 30.2 0.5 0.00042 20.6 0.2 5.3 4 1 2 6 6 6 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 OQS04675.1 - 0.00065 19.4 5.6 0.099 12.4 0.3 5.1 4 2 2 6 6 6 2 Leucine rich repeat LRR_1 PF00560.33 OQS04675.1 - 0.014 15.9 2.4 7.2 7.6 0.0 4.9 5 0 0 5 5 5 0 Leucine Rich Repeat Pkinase PF00069.25 OQS04678.1 - 1.1e-67 228.2 0.0 1.5e-67 227.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQS04678.1 - 1.4e-35 122.9 0.1 2e-35 122.4 0.1 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase PH_3 PF14593.6 OQS04678.1 - 4.2e-35 120.0 0.1 4.2e-35 120.0 0.1 1.7 2 0 0 2 2 2 1 PH domain Kinase-like PF14531.6 OQS04678.1 - 8.8e-07 28.5 0.0 3.8e-06 26.4 0.0 1.8 1 1 1 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 OQS04678.1 - 7.4e-06 25.0 0.0 1.3e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase FTA2 PF13095.6 OQS04678.1 - 0.0015 18.2 0.2 1.7 8.2 0.0 2.2 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 OQS04678.1 - 0.014 15.3 0.0 0.15 11.9 0.0 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 OQS04678.1 - 0.11 11.5 0.0 0.19 10.7 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 zf-C3HC4_3 PF13920.6 OQS04679.1 - 1.7e-11 43.8 6.4 1.7e-11 43.8 6.4 1.5 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) K-box PF01486.17 OQS04679.1 - 1.3e-05 25.3 9.0 1.3e-05 25.3 9.0 2.3 1 1 1 2 2 2 1 K-box region Prok-RING_4 PF14447.6 OQS04679.1 - 0.001 18.9 5.9 0.0019 18.0 5.9 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 CENP-F_leu_zip PF10473.9 OQS04679.1 - 0.0051 16.8 10.5 0.0074 16.3 10.5 1.3 1 0 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF4795 PF16043.5 OQS04679.1 - 0.0071 16.0 5.0 0.0091 15.6 5.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4795) zf-RING_2 PF13639.6 OQS04679.1 - 0.0076 16.6 5.7 0.014 15.7 5.7 1.5 1 0 0 1 1 1 1 Ring finger domain Mpv17_PMP22 PF04117.12 OQS04679.1 - 0.012 15.9 0.0 0.034 14.4 0.0 1.7 2 0 0 2 2 2 0 Mpv17 / PMP22 family DUF4709 PF15821.5 OQS04679.1 - 0.022 15.0 6.2 0.061 13.6 5.4 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4709) PHM7_cyt PF14703.6 OQS04679.1 - 0.15 12.3 1.5 0.2 11.9 1.5 1.3 1 0 0 1 1 1 0 Cytosolic domain of 10TM putative phosphate transporter Prefoldin_2 PF01920.20 OQS04679.1 - 0.25 11.3 9.7 1 9.4 1.9 2.2 1 1 1 2 2 2 0 Prefoldin subunit zf-RING_5 PF14634.6 OQS04679.1 - 0.31 11.0 4.9 0.68 9.9 4.9 1.6 1 0 0 1 1 1 0 zinc-RING finger domain HSCB_C PF07743.13 OQS04679.1 - 0.33 11.5 6.2 1.9 9.0 1.1 2.3 1 1 1 2 2 2 0 HSCB C-terminal oligomerisation domain Mitofilin PF09731.9 OQS04679.1 - 0.61 8.9 10.9 0.74 8.6 10.9 1.0 1 0 0 1 1 1 0 Mitochondrial inner membrane protein DUF1690 PF07956.11 OQS04679.1 - 2.6 8.4 9.1 5.8 7.3 9.0 1.7 1 1 0 1 1 1 0 Protein of Unknown function (DUF1690) Remorin_C PF03763.13 OQS04679.1 - 9.8 6.1 7.5 2.8 7.8 3.1 2.0 2 0 0 2 2 2 0 Remorin, C-terminal region p450 PF00067.22 OQS04680.1 - 1e-27 97.0 0.0 1.1e-27 96.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Glyco_transf_41 PF13844.6 OQS04681.1 - 1.6e-79 267.6 1.3 1e-38 133.0 0.9 2.1 2 0 0 2 2 2 2 Glycosyl transferase family 41 TPR_1 PF00515.28 OQS04681.1 - 0.056 13.3 0.1 0.13 12.2 0.1 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_MalT PF17874.1 OQS04681.1 - 0.16 11.3 0.1 0.38 10.1 0.0 1.7 2 0 0 2 2 2 0 MalT-like TPR region CUE PF02845.16 OQS04683.1 - 2.3e-05 24.0 0.0 4.5e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 CUE domain RB_B PF01857.20 OQS04684.1 - 0.25 11.4 10.3 0.68 10.0 10.3 1.8 1 1 0 1 1 1 0 Retinoblastoma-associated protein B domain NPR3 PF03666.13 OQS04684.1 - 9.7 4.9 25.8 13 4.4 25.8 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Skp1 PF01466.19 OQS04685.1 - 2.1e-10 40.5 0.1 1.3e-09 38.0 0.0 2.0 2 0 0 2 2 2 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.15 OQS04685.1 - 0.0008 19.5 0.0 0.0014 18.8 0.0 1.4 1 0 0 1 1 1 1 Skp1 family, tetramerisation domain TPR_1 PF00515.28 OQS04686.1 - 5.8e-19 67.0 7.0 4.7e-07 29.4 0.1 5.1 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_2 PF07719.17 OQS04686.1 - 1.4e-15 56.1 11.5 0.00031 20.6 0.0 5.5 5 1 0 5 5 5 4 Tetratricopeptide repeat TPR_8 PF13181.6 OQS04686.1 - 1.2e-13 50.1 9.0 8.4e-05 22.5 0.0 5.1 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_19 PF14559.6 OQS04686.1 - 9e-11 42.1 4.8 0.0012 19.3 0.0 3.3 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 OQS04686.1 - 3e-08 33.8 6.1 0.0029 17.9 0.3 3.3 2 2 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 OQS04686.1 - 7.3e-08 32.6 1.2 0.0028 18.3 0.1 3.7 2 2 2 4 4 4 1 Tetratricopeptide repeat TPR_17 PF13431.6 OQS04686.1 - 1.8e-06 27.9 8.6 0.48 10.9 0.1 4.4 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_11 PF13414.6 OQS04686.1 - 0.00011 21.9 22.2 0.0049 16.5 1.4 5.1 6 2 1 7 7 6 3 TPR repeat TPR_10 PF13374.6 OQS04686.1 - 0.00015 21.5 12.6 0.0088 15.9 0.1 4.3 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_7 PF13176.6 OQS04686.1 - 0.00021 21.1 7.4 0.042 13.9 0.1 3.9 4 1 0 4 4 3 2 Tetratricopeptide repeat TPR_6 PF13174.6 OQS04686.1 - 0.00029 21.3 7.8 0.35 11.6 0.3 4.5 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_9 PF13371.6 OQS04686.1 - 0.0018 18.4 2.5 3.3 7.9 0.0 3.7 2 2 1 3 3 3 1 Tetratricopeptide repeat TPR_MalT PF17874.1 OQS04686.1 - 0.0019 17.6 6.3 0.039 13.3 0.5 2.1 1 1 1 2 2 2 2 MalT-like TPR region ANAPC5 PF12862.7 OQS04686.1 - 0.014 15.4 4.3 0.081 13.0 0.3 2.5 1 1 1 2 2 2 0 Anaphase-promoting complex subunit 5 SMBP PF16785.5 OQS04686.1 - 0.045 14.0 0.8 1.1 9.6 0.0 2.3 1 1 0 2 2 2 0 Small metal-binding protein TPR_4 PF07721.14 OQS04686.1 - 0.058 14.0 1.9 1.5 9.7 0.0 3.3 5 0 0 5 5 2 0 Tetratricopeptide repeat DUF3856 PF12968.7 OQS04686.1 - 0.07 13.2 0.0 0.23 11.5 0.0 2.1 1 1 1 2 2 2 0 Domain of Unknown Function (DUF3856) NARP1 PF12569.8 OQS04686.1 - 0.075 11.9 4.3 0.11 11.4 1.3 2.0 2 0 0 2 2 2 0 NMDA receptor-regulated protein 1 DUF2225 PF09986.9 OQS04686.1 - 0.13 12.0 1.2 0.3 10.8 1.2 1.6 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2225) TPR_16 PF13432.6 OQS04686.1 - 0.29 11.8 2.9 6 7.6 0.1 3.1 2 2 2 4 4 4 0 Tetratricopeptide repeat HECT PF00632.25 OQS04687.1 - 1.5e-66 225.0 0.0 3.4e-66 223.8 0.0 1.6 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) FN3_7 PF18447.1 OQS04687.1 - 0.066 13.5 1.3 0.87 9.9 0.2 2.6 2 0 0 2 2 2 0 Fibronectin type III domain DUF4550 PF15084.6 OQS04687.1 - 0.085 13.3 0.1 0.27 11.7 0.1 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4550) GST_N_3 PF13417.6 OQS04688.1 - 2.1e-14 53.7 0.0 3.9e-14 52.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 OQS04688.1 - 6.1e-14 52.1 0.0 1.1e-13 51.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 OQS04688.1 - 1.6e-11 44.3 0.0 3.6e-11 43.2 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 OQS04688.1 - 1.1e-07 32.0 0.0 2e-07 31.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 OQS04688.1 - 1.8e-07 31.1 0.0 4.4e-07 29.8 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 OQS04688.1 - 1.7e-05 25.0 0.1 3.2e-05 24.1 0.1 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Glutaredoxin PF00462.24 OQS04688.1 - 0.054 13.7 0.0 0.19 12.0 0.0 2.0 1 0 0 1 1 1 0 Glutaredoxin TB2_DP1_HVA22 PF03134.19 OQS04688.1 - 0.091 12.7 0.1 0.18 11.7 0.1 1.4 1 0 0 1 1 1 0 TB2/DP1, HVA22 family EF_assoc_2 PF08356.12 OQS04688.1 - 0.12 12.4 0.0 0.88 9.6 0.0 2.1 1 1 0 1 1 1 0 EF hand associated Nudc_N PF14050.6 OQS04689.1 - 1e-21 76.7 0.0 1.5e-21 76.1 0.0 1.3 1 0 0 1 1 1 1 N-terminal conserved domain of Nudc. CS PF04969.16 OQS04689.1 - 6.7e-18 65.5 0.9 1.3e-17 64.6 0.9 1.5 1 0 0 1 1 1 1 CS domain DUF4097 PF13349.6 OQS04689.1 - 0.033 13.6 0.2 0.04 13.3 0.2 1.1 1 0 0 1 1 1 0 Putative adhesin PI3_PI4_kinase PF00454.27 OQS04690.1 - 4e-50 171.0 0.2 2e-48 165.4 0.2 2.7 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.20 OQS04690.1 - 1.6e-33 115.7 2.6 3e-33 114.8 2.6 1.4 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3K_C2 PF00792.24 OQS04690.1 - 6.7e-05 22.8 0.0 0.00019 21.3 0.0 1.7 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 PI3K_rbd PF00794.18 OQS04690.1 - 0.00014 21.9 0.3 0.00045 20.4 0.1 2.0 2 0 0 2 2 2 1 PI3-kinase family, ras-binding domain DUF4135 PF13575.6 OQS04690.1 - 0.0052 16.1 0.0 0.0092 15.3 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4135) WW PF00397.26 OQS04690.1 - 0.041 14.0 0.0 0.13 12.4 0.0 1.8 2 0 0 2 2 2 0 WW domain Pkinase_Tyr PF07714.17 OQS04691.1 - 3.2e-35 121.7 0.0 1.3e-31 109.9 0.0 2.1 1 1 1 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 OQS04691.1 - 2.7e-33 115.5 0.0 8.1e-30 104.1 0.0 2.1 1 1 1 2 2 2 2 Protein kinase domain APH PF01636.23 OQS04691.1 - 0.041 13.8 0.0 0.16 11.9 0.0 1.8 1 1 0 1 1 1 0 Phosphotransferase enzyme family RPEL PF02755.15 OQS04691.1 - 0.17 11.6 3.2 12 5.7 0.1 3.6 3 0 0 3 3 3 0 RPEL repeat Asp_Arg_Hydrox PF05118.15 OQS04692.1 - 1.1e-46 158.6 0.1 1.5e-46 158.1 0.1 1.2 1 0 0 1 1 1 1 Aspartyl/Asparaginyl beta-hydroxylase Ribosomal_S13_N PF08069.12 OQS04692.1 - 3e-31 107.2 0.4 5.2e-31 106.5 0.4 1.4 1 0 0 1 1 1 1 Ribosomal S13/S15 N-terminal domain Ribosomal_S15 PF00312.22 OQS04692.1 - 8.3e-08 32.3 0.2 1.4e-07 31.6 0.2 1.3 1 0 0 1 1 1 1 Ribosomal protein S15 Tubulin PF00091.25 OQS04693.1 - 6.7e-63 212.5 0.0 9.3e-63 212.0 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 OQS04693.1 - 5.7e-26 91.1 0.0 8.8e-26 90.5 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_2 PF13809.6 OQS04693.1 - 0.0069 15.6 0.0 0.011 15.0 0.0 1.2 1 0 0 1 1 1 1 Tubulin like Tubulin_3 PF14881.6 OQS04693.1 - 0.017 14.8 0.0 0.035 13.8 0.0 1.5 1 0 0 1 1 1 0 Tubulin domain Misat_Tub_SegII PF10644.9 OQS04693.1 - 0.017 15.4 0.0 0.035 14.4 0.0 1.6 1 0 0 1 1 1 0 Misato Segment II tubulin-like domain Pkinase PF00069.25 OQS04694.1 - 1e-99 333.2 0.0 8.8e-49 166.2 0.0 2.0 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OQS04694.1 - 9e-60 202.1 0.1 2.3e-31 109.0 0.1 2.3 1 1 2 3 3 3 2 Protein tyrosine kinase Kinase-like PF14531.6 OQS04694.1 - 2.1e-08 33.8 0.1 0.0037 16.6 0.0 2.6 3 0 0 3 3 3 2 Kinase-like Kdo PF06293.14 OQS04694.1 - 2.6e-08 33.5 0.7 0.00023 20.6 0.3 2.2 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OQS04694.1 - 3.9e-07 30.2 0.4 0.38 10.6 0.0 4.1 2 2 2 4 4 4 2 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.9 OQS04694.1 - 1.7e-06 27.7 0.2 0.00063 19.3 0.2 2.6 3 0 0 3 3 3 2 PhoP regulatory network protein YrbL RIO1 PF01163.22 OQS04694.1 - 4.1e-06 26.5 0.1 0.026 14.1 0.1 2.5 2 0 0 2 2 2 2 RIO1 family Haspin_kinase PF12330.8 OQS04694.1 - 0.0013 17.8 2.1 0.25 10.3 0.0 2.6 2 1 0 3 3 3 2 Haspin like kinase domain IclR PF01614.18 OQS04694.1 - 0.027 14.3 0.1 0.055 13.3 0.1 1.4 1 0 0 1 1 1 0 Bacterial transcriptional regulator DUF3541 PF12060.8 OQS04694.1 - 0.043 13.5 0.4 2.8 7.6 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3541) Pkinase_fungal PF17667.1 OQS04694.1 - 0.063 12.0 0.1 2.5 6.8 0.1 2.2 2 0 0 2 2 2 0 Fungal protein kinase DnaJ_C PF01556.18 OQS04695.1 - 1.5e-27 96.5 0.2 1.8e-27 96.2 0.2 1.1 1 0 0 1 1 1 1 DnaJ C terminal domain VanZ PF04892.12 OQS04696.1 - 5.4e-10 40.0 1.0 7.5e-10 39.5 1.0 1.3 1 1 0 1 1 1 1 VanZ like family DUF2279 PF10043.9 OQS04696.1 - 0.0083 16.9 0.5 0.02 15.7 0.5 1.7 1 1 0 1 1 1 1 Predicted periplasmic lipoprotein (DUF2279) Sensor PF13796.6 OQS04696.1 - 0.013 15.5 2.1 0.013 15.5 2.1 1.7 2 0 0 2 2 2 0 Putative sensor TLD PF07534.16 OQS04697.1 - 4.7e-27 94.9 0.1 8.1e-27 94.1 0.1 1.4 1 0 0 1 1 1 1 TLD PDZ_6 PF17820.1 OQS04697.1 - 1.4e-09 37.6 0.0 3e-06 27.0 0.0 2.8 3 0 0 3 3 3 2 PDZ domain PDZ PF00595.24 OQS04697.1 - 9.6e-09 35.5 0.0 0.0021 18.3 0.0 2.3 2 0 0 2 2 2 2 PDZ domain PDZ_2 PF13180.6 OQS04697.1 - 0.081 13.2 0.0 3.7 7.9 0.0 2.3 2 0 0 2 2 2 0 PDZ domain DnaJ_C PF01556.18 OQS04698.1 - 1.1e-40 139.2 0.6 1.4e-40 138.8 0.6 1.1 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 OQS04698.1 - 1.2e-21 76.5 0.1 2.3e-21 75.7 0.1 1.5 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 OQS04698.1 - 1.1e-15 57.7 19.4 2e-15 56.9 19.4 1.4 1 0 0 1 1 1 1 DnaJ central domain HypA PF01155.19 OQS04698.1 - 0.039 14.0 7.1 1.5 8.8 1.9 2.5 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Anti-TRAP PF15777.5 OQS04698.1 - 2.1 8.3 15.6 0.69 9.9 2.3 2.8 1 1 2 3 3 3 0 Tryptophan RNA-binding attenuator protein inhibitory protein zf-RING_10 PF16685.5 OQS04698.1 - 4.5 7.5 8.4 0.49 10.6 1.7 2.3 1 1 1 2 2 2 0 zinc RING finger of MSL2 zinc-ribbons_6 PF07191.12 OQS04698.1 - 9.6 6.3 9.0 16 5.6 2.2 2.3 1 1 1 2 2 2 0 zinc-ribbons GCP_N_terminal PF17681.1 OQS04699.1 - 3.4e-82 276.5 0.0 6.2e-82 275.7 0.0 1.5 1 0 0 1 1 1 1 Gamma tubulin complex component N-terminal GCP_C_terminal PF04130.13 OQS04699.1 - 5.4e-82 275.7 9.8 1e-81 274.8 9.8 1.5 1 0 0 1 1 1 1 Gamma tubulin complex component C-terminal GDPD PF03009.17 OQS04699.1 - 4.9e-19 69.1 0.0 1.6e-18 67.4 0.0 2.0 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family Membr_traf_MHD PF10540.9 OQS04699.1 - 0.091 12.9 0.7 13 5.9 0.0 3.1 3 0 0 3 3 3 0 Munc13 (mammalian uncoordinated) homology domain Myosin_head PF00063.21 OQS04700.1 - 0 1471.6 4.1 1.2e-224 747.6 0.4 2.2 2 0 0 2 2 2 2 Myosin head (motor domain) IQ PF00612.27 OQS04700.1 - 8.7e-10 37.5 39.5 0.0011 18.6 1.1 6.7 6 0 0 6 6 6 5 IQ calmodulin-binding motif PDZ_6 PF17820.1 OQS04700.1 - 1e-09 38.0 0.0 0.0021 17.8 0.0 5.4 5 0 0 5 5 5 2 PDZ domain PDZ_2 PF13180.6 OQS04700.1 - 1.2e-06 28.8 0.6 2.1 8.7 0.0 5.6 6 0 0 6 6 6 2 PDZ domain GOLD_2 PF13897.6 OQS04700.1 - 1.8e-05 25.3 0.4 0.014 15.9 0.0 3.1 1 1 1 2 2 2 1 Golgi-dynamics membrane-trafficking AAA_22 PF13401.6 OQS04700.1 - 0.00014 22.2 0.3 1.2 9.4 0.0 3.4 3 0 0 3 3 2 2 AAA domain PDZ PF00595.24 OQS04700.1 - 0.00014 22.2 0.1 0.042 14.2 0.0 4.4 5 0 0 5 5 4 1 PDZ domain AAA_19 PF13245.6 OQS04700.1 - 0.0002 21.7 0.2 0.77 10.1 0.0 3.3 3 0 0 3 3 2 2 AAA domain T2SSE PF00437.20 OQS04700.1 - 0.00044 19.4 1.4 0.57 9.2 0.0 2.9 3 0 0 3 3 3 2 Type II/IV secretion system protein TsaE PF02367.17 OQS04700.1 - 0.00067 19.7 0.0 2 8.4 0.0 2.6 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_6 PF12774.7 OQS04700.1 - 0.0011 18.0 0.2 0.78 8.6 0.1 2.6 2 0 0 2 2 2 2 Hydrolytic ATP binding site of dynein motor region Zeta_toxin PF06414.12 OQS04700.1 - 0.0015 17.8 0.0 1.6 8.0 0.0 2.7 2 0 0 2 2 2 2 Zeta toxin Sigma54_activat PF00158.26 OQS04700.1 - 0.0044 16.8 0.0 3.5 7.3 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain RNA_helicase PF00910.22 OQS04700.1 - 0.005 17.2 0.0 5.8 7.3 0.0 3.0 2 0 0 2 2 2 1 RNA helicase Rad17 PF03215.15 OQS04700.1 - 0.014 15.3 0.0 4 7.3 0.0 2.6 2 0 0 2 2 2 0 Rad17 P-loop domain ABC_tran PF00005.27 OQS04700.1 - 0.017 15.6 6.1 2.8 8.5 0.0 3.8 4 1 0 4 4 2 0 ABC transporter CbiA PF01656.23 OQS04700.1 - 0.05 13.7 0.5 7 6.7 0.0 3.1 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_18 PF13238.6 OQS04700.1 - 0.073 13.6 5.1 4.5 7.8 0.0 4.2 3 0 0 3 3 3 0 AAA domain Hpr_kinase_C PF07475.12 OQS04700.1 - 0.11 12.1 0.7 61 3.1 0.0 3.7 4 0 0 4 4 4 0 HPr Serine kinase C-terminal domain AAA_29 PF13555.6 OQS04700.1 - 0.12 12.1 0.0 25 4.7 0.0 2.6 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_16 PF13191.6 OQS04700.1 - 0.15 12.5 12.4 1.8 8.9 0.0 5.0 5 0 0 5 5 4 0 AAA ATPase domain DUF1931 PF09123.11 OQS04700.1 - 0.32 11.1 4.0 0.43 10.7 0.4 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF1931) DUF87 PF01935.17 OQS04700.1 - 3.8 7.5 9.4 20 5.2 0.1 4.2 4 0 0 4 4 4 0 Helicase HerA, central domain DIX PF00778.17 OQS04702.1 - 9.5e-06 25.4 0.0 1.5e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 DIX domain Pkinase PF00069.25 OQS04703.1 - 4.9e-52 176.9 0.0 7.2e-52 176.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQS04703.1 - 2e-37 128.9 0.0 3e-37 128.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase HAGH_C PF16123.5 OQS04704.1 - 3.1e-25 88.5 0.0 5.3e-25 87.7 0.0 1.4 1 0 0 1 1 1 1 Hydroxyacylglutathione hydrolase C-terminus Lactamase_B PF00753.27 OQS04704.1 - 1.4e-10 41.5 0.7 2.4e-10 40.8 0.7 1.4 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 OQS04704.1 - 0.0021 17.6 0.0 0.0079 15.7 0.0 1.9 1 1 0 1 1 1 1 Beta-lactamase superfamily domain CEP19 PF14933.6 OQS04705.1 - 2e-20 73.7 3.7 3.3e-13 50.3 0.6 2.0 1 1 1 2 2 2 2 CEP19-like protein SNF2_N PF00176.23 OQS04706.1 - 1.5e-57 195.0 1.0 2.8e-57 194.0 1.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 OQS04706.1 - 4.5e-18 65.6 0.0 1.6e-17 63.9 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Chromo PF00385.24 OQS04706.1 - 1.9e-14 53.3 3.4 3.7e-09 36.3 0.5 2.9 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain ResIII PF04851.15 OQS04706.1 - 1e-06 28.9 1.8 8.7e-06 25.8 0.0 2.7 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DUF1086 PF06461.11 OQS04706.1 - 0.082 12.8 0.0 4.8 7.0 0.0 2.6 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1086) PH PF00169.29 OQS04707.1 - 4.5e-11 43.2 0.1 1.5e-10 41.5 0.0 1.9 2 0 0 2 2 2 1 PH domain GBP_C PF02841.14 OQS04707.1 - 3.7e-08 33.1 3.4 7.1e-08 32.2 3.4 1.4 1 0 0 1 1 1 1 Guanylate-binding protein, C-terminal domain Syntaxin-6_N PF09177.11 OQS04707.1 - 0.014 15.9 0.9 0.035 14.7 0.9 1.8 1 0 0 1 1 1 0 Syntaxin 6, N-terminal CpxA_peri PF16527.5 OQS04707.1 - 0.021 15.2 1.3 0.78 10.1 0.0 3.3 4 0 0 4 4 4 0 Two-component sensor protein CpxA, periplasmic domain FapA PF03961.13 OQS04707.1 - 0.28 9.7 4.9 0.42 9.2 4.9 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A Spectrin PF00435.21 OQS04707.1 - 0.32 11.5 6.9 0.68 10.5 6.9 1.6 1 0 0 1 1 1 0 Spectrin repeat ParB PF08775.10 OQS04707.1 - 0.41 11.1 4.4 0.9 10.0 2.6 2.5 2 0 0 2 2 2 0 ParB family PH_11 PF15413.6 OQS04707.1 - 0.52 10.8 3.4 0.84 10.1 0.5 2.8 2 1 0 2 2 2 0 Pleckstrin homology domain PDZ PF00595.24 OQS04708.1 - 1.2e-17 64.0 0.0 3.2e-05 24.2 0.0 5.0 5 0 0 5 5 5 3 PDZ domain PDZ_6 PF17820.1 OQS04708.1 - 3.2e-10 39.7 0.0 0.02 14.7 0.0 4.7 4 0 0 4 4 4 4 PDZ domain Tudor_3 PF18115.1 OQS04708.1 - 0.0042 16.9 0.0 0.015 15.2 0.0 1.9 2 0 0 2 2 2 1 DNA repair protein Crb2 Tudor domain PDZ_2 PF13180.6 OQS04708.1 - 0.047 14.0 0.0 10 6.5 0.0 3.1 3 0 0 3 3 3 0 PDZ domain Autophagy_C PF10381.9 OQS04708.1 - 0.078 12.5 0.2 0.19 11.3 0.2 1.7 1 0 0 1 1 1 0 Autophagocytosis associated protein C-terminal LBR_tudor PF09465.10 OQS04708.1 - 0.084 12.7 0.0 0.29 11.0 0.0 1.9 2 0 0 2 2 2 0 Lamin-B receptor of TUDOR domain DUF445 PF04286.12 OQS04708.1 - 0.096 12.5 11.3 0.048 13.5 8.8 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF445) CBM_1 PF00734.18 OQS04709.1 - 6.2e-15 54.9 20.4 3.4e-11 42.9 7.6 4.8 5 0 0 5 5 5 2 Fungal cellulose binding domain PAN_4 PF14295.6 OQS04709.1 - 1.2e-06 28.3 26.3 0.00026 20.8 6.1 3.8 4 0 0 4 4 4 2 PAN domain PT PF04886.12 OQS04709.1 - 4.6e-05 22.9 89.8 0.0044 16.5 31.0 4.2 1 1 2 3 3 3 2 PT repeat Bact_transglu_N PF08379.10 OQS04709.1 - 0.0022 18.8 0.1 1.6 9.7 0.0 2.8 2 0 0 2 2 2 2 Bacterial transglutaminase-like N-terminal region Nucleoside_tran PF01733.18 OQS04710.1 - 7.5e-29 101.1 7.2 1.5e-28 100.1 7.2 1.5 1 0 0 1 1 1 1 Nucleoside transporter Leu_Phe_trans PF03588.14 OQS04710.1 - 0.044 13.3 0.2 0.073 12.6 0.2 1.3 1 0 0 1 1 1 0 Leucyl/phenylalanyl-tRNA protein transferase DUF1772 PF08592.11 OQS04710.1 - 1.4 9.2 6.1 4.4 7.6 3.8 2.7 1 1 0 1 1 1 0 Domain of unknown function (DUF1772) Allexi_40kDa PF05549.11 OQS04711.1 - 0.0011 18.5 2.5 0.0013 18.3 2.5 1.1 1 0 0 1 1 1 1 Allexivirus 40kDa protein EzrA PF06160.12 OQS04711.1 - 0.0014 17.0 1.3 0.0014 16.9 1.3 1.0 1 0 0 1 1 1 1 Septation ring formation regulator, EzrA phiKZ_IP PF12699.7 OQS04711.1 - 0.0023 17.2 0.2 0.0027 16.9 0.2 1.1 1 0 0 1 1 1 1 phiKZ-like phage internal head proteins DUF848 PF05852.11 OQS04711.1 - 0.059 13.5 0.4 0.076 13.1 0.4 1.2 1 0 0 1 1 1 0 Gammaherpesvirus protein of unknown function (DUF848) YojJ PF10372.9 OQS04711.1 - 0.072 13.2 0.9 0.16 12.1 0.9 1.5 1 0 0 1 1 1 0 Bacterial membrane-spanning protein N-terminus TPR_11 PF13414.6 OQS04711.1 - 0.2 11.4 0.0 0.35 10.6 0.0 1.4 1 0 0 1 1 1 0 TPR repeat DUF525 PF04379.14 OQS04712.1 - 1.8e-12 47.3 0.0 3.6e-12 46.4 0.0 1.5 1 0 0 1 1 1 1 ApaG domain F-box-like PF12937.7 OQS04712.1 - 1.1e-06 28.4 1.5 2.2e-06 27.5 1.5 1.4 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 OQS04712.1 - 0.0001 22.1 0.3 0.00022 21.0 0.3 1.6 1 0 0 1 1 1 1 F-box domain F-box_5 PF18511.1 OQS04712.1 - 0.0015 18.1 0.1 0.0037 16.8 0.1 1.7 1 0 0 1 1 1 1 F-box DUF1949 PF09186.11 OQS04712.1 - 0.076 12.9 0.0 0.16 11.9 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1949) PPR_2 PF13041.6 OQS04713.1 - 2e-39 133.5 18.4 3e-07 30.5 0.0 11.8 9 3 3 12 12 12 7 PPR repeat family PPR PF01535.20 OQS04713.1 - 3.5e-28 95.8 8.1 0.0011 19.0 0.2 13.0 13 0 0 13 13 13 6 PPR repeat PPR_3 PF13812.6 OQS04713.1 - 7.8e-23 80.3 5.9 0.00013 22.0 0.0 9.0 6 2 3 9 9 9 6 Pentatricopeptide repeat domain PPR_long PF17177.4 OQS04713.1 - 1.6e-14 53.8 10.7 0.00017 21.0 0.0 6.1 4 3 0 5 5 5 3 Pentacotripeptide-repeat region of PRORP PPR_1 PF12854.7 OQS04713.1 - 7.8e-09 35.1 8.4 0.022 14.5 0.0 9.3 10 0 0 10 10 10 2 PPR repeat Cyclin_C_2 PF16899.5 OQS04713.1 - 1.3e-08 35.1 0.1 1.2e-07 32.0 0.0 2.7 2 0 0 2 2 2 1 Cyclin C-terminal domain DED PF01335.21 OQS04713.1 - 1.5e-05 25.2 4.2 2 8.8 0.1 7.0 7 1 2 9 9 9 1 Death effector domain Cyclin_N PF00134.23 OQS04713.1 - 4.5e-05 23.2 0.1 0.00014 21.6 0.1 1.9 1 0 0 1 1 1 1 Cyclin, N-terminal domain TFIIB PF00382.19 OQS04713.1 - 0.0054 16.8 0.0 0.03 14.3 0.0 2.4 2 0 0 2 2 2 1 Transcription factor TFIIB repeat TPR_14 PF13428.6 OQS04713.1 - 0.0065 17.2 3.1 18 6.5 0.1 6.7 5 3 3 8 8 7 0 Tetratricopeptide repeat DUF2560 PF10834.8 OQS04713.1 - 0.018 15.2 0.1 0.32 11.2 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2560) TPR_19 PF14559.6 OQS04713.1 - 1.3 9.6 6.5 19 5.8 0.0 5.6 5 2 1 6 6 6 0 Tetratricopeptide repeat PI3_PI4_kinase PF00454.27 OQS04715.1 - 2.1e-37 129.3 0.0 3.2e-37 128.7 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase TFR_dimer PF04253.15 OQS04715.1 - 2.2e-23 82.7 0.0 4.7e-23 81.6 0.0 1.5 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain DIOX_N PF14226.6 OQS04715.1 - 4.2e-18 66.2 0.0 8.6e-18 65.2 0.0 1.6 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 OQS04715.1 - 1.4e-16 60.8 0.1 7.7e-16 58.4 0.0 2.3 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily PA PF02225.22 OQS04715.1 - 9.8e-08 31.9 0.1 2.5e-07 30.6 0.1 1.7 1 0 0 1 1 1 1 PA domain Peptidase_M28 PF04389.17 OQS04715.1 - 4.9e-05 23.1 0.0 0.00015 21.5 0.0 1.8 2 0 0 2 2 2 1 Peptidase family M28 Pkinase_Tyr PF07714.17 OQS04718.1 - 2e-41 142.0 0.2 2.7e-41 141.6 0.2 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OQS04718.1 - 1.6e-30 106.4 0.4 2.6e-30 105.7 0.4 1.2 1 0 0 1 1 1 1 Protein kinase domain Seadorna_VP7 PF07387.11 OQS04718.1 - 0.00018 20.7 0.0 0.00037 19.7 0.0 1.5 1 0 0 1 1 1 1 Seadornavirus VP7 Kinase-like PF14531.6 OQS04718.1 - 0.0039 16.5 0.5 0.009 15.4 0.1 1.6 1 1 1 2 2 2 1 Kinase-like Kdo PF06293.14 OQS04718.1 - 0.012 15.0 0.0 0.023 14.0 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family IQ PF00612.27 OQS04719.1 - 0.00089 18.8 23.4 0.08 12.8 0.9 5.5 4 0 0 4 4 4 3 IQ calmodulin-binding motif RTX_C PF08339.10 OQS04719.1 - 0.15 12.1 0.2 7.2 6.6 0.0 2.5 2 0 0 2 2 2 0 RTX C-terminal domain SieB PF14163.6 OQS04719.1 - 0.28 10.7 1.6 0.81 9.2 1.6 1.8 1 0 0 1 1 1 0 Super-infection exclusion protein B TFIIF_beta PF02270.15 OQS04720.1 - 2.3e-22 78.9 0.4 3.9e-22 78.2 0.4 1.4 1 0 0 1 1 1 1 TFIIF, beta subunit HTH domain TFIIF_beta_N PF17683.1 OQS04720.1 - 0.007 17.0 0.5 0.036 14.8 0.5 2.5 1 1 0 1 1 1 1 TFIIF, beta subunit N-terminus DDE_Tnp_IS66_C PF13817.6 OQS04720.1 - 0.0081 16.4 0.0 0.02 15.1 0.0 1.7 1 0 0 1 1 1 1 IS66 C-terminal element DEAD PF00270.29 OQS04721.1 - 3.4e-40 137.7 0.1 9.5e-40 136.2 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OQS04721.1 - 8e-29 100.2 0.0 1.6e-27 96.0 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 OQS04721.1 - 1.9e-08 34.5 1.5 1.4e-05 25.2 0.0 2.5 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit BUD22 PF09073.10 OQS04721.1 - 9.5 5.4 44.1 5 6.4 34.8 2.2 2 0 0 2 2 2 0 BUD22 Auto_anti-p27 PF06677.12 OQS04724.1 - 0.00036 20.6 0.9 0.053 13.7 0.1 2.2 2 0 0 2 2 2 2 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) TackOD1 PF18551.1 OQS04724.1 - 0.013 15.2 1.0 0.024 14.3 1.0 1.4 1 0 0 1 1 1 0 Thaumarchaeal output domain 1 Ank_5 PF13857.6 OQS04724.1 - 0.036 14.4 0.1 0.14 12.6 0.0 2.0 2 0 0 2 2 2 0 Ankyrin repeats (many copies) Ank_2 PF12796.7 OQS04724.1 - 0.036 14.6 0.1 0.08 13.5 0.1 1.7 1 1 0 1 1 1 0 Ankyrin repeats (3 copies) Peptidase_C12 PF01088.21 OQS04724.1 - 0.047 13.4 0.0 0.049 13.4 0.0 1.1 1 0 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase, family 1 DZR PF12773.7 OQS04724.1 - 0.05 13.6 0.6 0.094 12.8 0.6 1.4 1 0 0 1 1 1 0 Double zinc ribbon DUF2614 PF11023.8 OQS04724.1 - 0.05 13.7 0.7 0.086 12.9 0.7 1.3 1 0 0 1 1 1 0 Zinc-ribbon containing domain Ank_4 PF13637.6 OQS04724.1 - 0.11 13.1 0.1 0.32 11.6 0.0 1.8 2 0 0 2 2 2 0 Ankyrin repeats (many copies) PH PF00169.29 OQS04725.1 - 9.3e-15 55.0 0.0 1.2e-14 54.7 0.0 1.1 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 OQS04725.1 - 1.6e-07 31.7 0.0 2e-07 31.4 0.0 1.2 1 0 0 1 1 1 1 Pleckstrin homology domain PH_3 PF14593.6 OQS04725.1 - 0.0021 18.1 0.0 0.042 14.0 0.0 2.0 1 1 0 1 1 1 1 PH domain PH_8 PF15409.6 OQS04725.1 - 0.0029 17.8 0.4 0.019 15.2 0.3 2.2 1 1 0 1 1 1 1 Pleckstrin homology domain PH_9 PF15410.6 OQS04725.1 - 0.0063 16.9 0.2 0.72 10.2 0.2 2.2 1 1 0 1 1 1 1 Pleckstrin homology domain Mcp5_PH PF12814.7 OQS04725.1 - 0.056 13.6 0.0 0.067 13.3 0.0 1.3 1 0 0 1 1 1 0 Meiotic cell cortex C-terminal pleckstrin homology PH PF00169.29 OQS04726.1 - 1.6e-13 51.1 0.0 2.5e-13 50.4 0.0 1.3 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 OQS04726.1 - 0.00024 21.5 0.1 0.00065 20.1 0.1 1.8 1 1 0 1 1 1 1 Pleckstrin homology domain PH_8 PF15409.6 OQS04726.1 - 0.0032 17.7 0.1 0.018 15.3 0.1 2.0 1 1 0 1 1 1 1 Pleckstrin homology domain PH_9 PF15410.6 OQS04726.1 - 0.014 15.8 0.0 0.28 11.6 0.0 2.2 1 1 0 1 1 1 0 Pleckstrin homology domain PH_3 PF14593.6 OQS04726.1 - 0.071 13.2 0.0 0.38 10.9 0.0 2.0 1 1 0 1 1 1 0 PH domain MerE PF05052.12 OQS04727.1 - 0.00065 19.6 1.9 0.00065 19.6 1.9 1.6 2 0 0 2 2 2 1 MerE protein HupE_UreJ_2 PF13795.6 OQS04727.1 - 0.0015 18.2 0.3 0.0021 17.7 0.3 1.2 1 0 0 1 1 1 1 HupE / UreJ protein O-antigen_lig PF13425.6 OQS04727.1 - 0.0083 15.0 0.0 0.0089 14.9 0.0 1.1 1 0 0 1 1 1 1 O-antigen ligase like membrane protein YtpI PF14007.6 OQS04727.1 - 0.13 12.4 1.3 0.26 11.4 0.9 1.7 1 1 0 1 1 1 0 YtpI-like protein HupE_UreJ PF04955.12 OQS04727.1 - 0.19 11.2 5.9 0.28 10.7 5.9 1.2 1 0 0 1 1 1 0 HupE / UreJ protein DUF4763 PF15960.5 OQS04727.1 - 1.8 7.8 5.8 27 4.0 5.2 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4763) CPBP PF02517.16 OQS04727.1 - 2.2 8.7 5.1 21 5.5 5.1 2.1 1 1 0 1 1 1 0 CPBP intramembrane metalloprotease RbsD_FucU PF05025.13 OQS04729.1 - 4.7e-34 117.7 0.0 5.4e-34 117.5 0.0 1.0 1 0 0 1 1 1 1 RbsD / FucU transport protein family Glyoxalase_4 PF13669.6 OQS04730.1 - 3.2e-19 69.2 0.0 4.9e-19 68.6 0.0 1.3 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase PF00903.25 OQS04730.1 - 0.077 13.2 0.0 0.11 12.6 0.0 1.4 1 0 0 1 1 1 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Pkinase PF00069.25 OQS04731.1 - 5e-26 91.6 0.1 5.3e-26 91.6 0.1 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQS04731.1 - 8.3e-23 81.0 0.0 9.1e-23 80.8 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 OQS04731.1 - 0.00089 18.7 0.0 0.0012 18.3 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 OQS04731.1 - 0.095 11.6 0.0 0.12 11.3 0.0 1.1 1 0 0 1 1 1 0 Haspin like kinase domain Nse4_C PF08743.10 OQS04732.1 - 3.8e-21 75.1 0.2 1.8e-20 73.0 0.0 2.1 2 0 0 2 2 2 1 Nse4 C-terminal RES PF08808.11 OQS04732.1 - 0.0012 18.8 0.0 0.0018 18.2 0.0 1.3 1 0 0 1 1 1 1 RES domain CM_1 PF07736.11 OQS04732.1 - 0.026 14.9 0.2 0.072 13.5 0.2 1.8 1 0 0 1 1 1 0 Chorismate mutase type I Nucleoside_tran PF01733.18 OQS04733.1 - 6.5e-45 153.8 35.1 2.3e-23 83.1 15.4 3.8 2 2 0 2 2 2 2 Nucleoside transporter TssO PF17561.2 OQS04733.1 - 4.7e-05 23.5 3.6 0.16 12.0 0.1 2.8 2 0 0 2 2 2 2 Type VI secretion system, TssO LPG_synthase_TM PF03706.13 OQS04733.1 - 7.5e-05 22.4 5.8 0.00073 19.2 1.1 5.1 6 0 0 6 6 6 2 Lysylphosphatidylglycerol synthase TM region PufQ PF05398.11 OQS04733.1 - 0.035 14.2 2.6 2.4 8.3 0.2 2.7 2 0 0 2 2 2 0 PufQ cytochrome subunit DUF3566 PF12089.8 OQS04733.1 - 6.1 7.2 14.9 0.3 11.4 0.3 3.8 4 0 0 4 4 4 0 Transmembrane domain of unknown function (DUF3566) PDDEXK_3 PF13366.6 OQS04735.1 - 9.3e-29 100.2 0.1 1.5e-28 99.5 0.1 1.3 1 0 0 1 1 1 1 PD-(D/E)XK nuclease superfamily Cas_Cas4 PF01930.17 OQS04735.1 - 0.042 13.9 0.4 9.1 6.4 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function DUF83 Nucleoside_tran PF01733.18 OQS04736.1 - 1.7e-17 63.8 8.2 3.7e-16 59.4 8.2 2.2 1 1 0 1 1 1 1 Nucleoside transporter DUF4149 PF13664.6 OQS04736.1 - 0.34 11.3 10.1 11 6.4 0.0 4.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4149) YlaH PF14036.6 OQS04736.1 - 4 7.8 9.1 0.6 10.5 0.3 3.3 3 0 0 3 3 3 0 YlaH-like protein GTP_EFTU PF00009.27 OQS04737.1 - 8.5e-43 146.2 0.0 9.9e-43 145.9 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 OQS04737.1 - 1.1e-28 99.8 0.1 1.7e-27 95.9 0.0 2.7 3 0 0 3 3 3 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 OQS04737.1 - 2e-11 44.1 0.1 8.3e-11 42.1 0.2 2.1 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 OQS04737.1 - 0.00082 19.4 0.1 0.0047 17.0 0.1 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 OQS04737.1 - 0.022 14.3 0.0 2.6 7.5 0.0 2.5 2 0 0 2 2 2 0 Ferrous iron transport protein B DUF1561 PF07598.11 OQS04737.1 - 0.084 11.1 0.0 0.19 9.9 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1561) Peptidase_C1 PF00112.23 OQS04738.1 - 1.5e-61 208.2 11.1 1.9e-61 207.9 11.1 1.1 1 0 0 1 1 1 1 Papain family cysteine protease PT PF04886.12 OQS04738.1 - 1.6e-29 101.1 102.3 1.8e+04 -48.3 102.3 6.2 1 1 0 1 1 1 0 PT repeat Peptidase_C1_2 PF03051.15 OQS04738.1 - 0.00031 19.7 2.0 0.021 13.6 0.1 2.1 2 0 0 2 2 2 2 Peptidase C1-like family Folate_rec PF03024.14 OQS04739.1 - 5.4e-15 55.7 9.8 8.1e-15 55.1 9.8 1.3 1 0 0 1 1 1 1 Folate receptor family Fz PF01392.22 OQS04739.1 - 0.027 15.1 11.2 0.077 13.6 11.2 1.8 1 1 0 1 1 1 0 Fz domain DUF4229 PF14012.6 OQS04739.1 - 0.047 13.8 0.0 0.065 13.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4229) DUF4266 PF14086.6 OQS04739.1 - 0.11 13.5 0.8 0.39 11.7 0.5 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4266) C2 PF00168.30 OQS04740.1 - 7.8e-33 112.9 0.0 2.6e-12 46.9 0.0 3.2 3 0 0 3 3 3 3 C2 domain Pkinase PF00069.25 OQS04741.1 - 3.5e-68 229.8 0.0 4.2e-68 229.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQS04741.1 - 3.2e-39 134.8 0.0 3.9e-39 134.5 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OQS04741.1 - 7e-08 32.1 0.0 8.1e-07 28.6 0.0 2.2 2 1 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 OQS04741.1 - 0.00017 20.5 0.0 0.00033 19.6 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 OQS04741.1 - 0.0029 17.0 0.9 0.0058 16.0 0.3 1.6 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 OQS04741.1 - 0.011 15.3 0.0 0.017 14.7 0.0 1.4 1 0 0 1 1 1 0 RIO1 family Choline_kinase PF01633.20 OQS04741.1 - 0.029 14.0 0.0 0.048 13.2 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase Pox_ser-thr_kin PF05445.11 OQS04741.1 - 0.029 13.3 0.0 0.068 12.1 0.0 1.5 2 0 0 2 2 2 0 Poxvirus serine/threonine protein kinase Haspin_kinase PF12330.8 OQS04741.1 - 0.06 12.3 0.1 0.079 11.9 0.1 1.1 1 0 0 1 1 1 0 Haspin like kinase domain FTA2 PF13095.6 OQS04741.1 - 0.084 12.5 0.2 2.3 7.8 0.1 2.2 1 1 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Kindlin_2_N PF18124.1 OQS04741.1 - 0.098 12.9 0.0 0.2 11.8 0.0 1.4 1 0 0 1 1 1 0 Kindlin-2 N-terminal domain Suf PF05843.14 OQS04742.1 - 1.1e-49 170.1 6.8 6e-49 167.6 1.2 3.6 3 1 1 4 4 4 1 Suppressor of forked protein (Suf) TPR_14 PF13428.6 OQS04742.1 - 2.7e-06 27.7 8.5 0.085 13.7 0.0 6.3 6 1 1 7 7 7 2 Tetratricopeptide repeat NRDE-2 PF08424.10 OQS04742.1 - 8.2e-06 25.2 11.2 0.24 10.5 0.0 5.3 1 1 2 5 5 5 3 NRDE-2, necessary for RNA interference TPR_6 PF13174.6 OQS04742.1 - 3.9e-05 24.0 2.5 0.3 11.8 0.0 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.6 OQS04742.1 - 0.00062 20.2 3.0 1.4 9.5 0.0 4.2 5 0 0 5 5 5 2 Tetratricopeptide repeat HAT PF02184.16 OQS04742.1 - 0.26 11.3 0.0 0.26 11.3 0.0 4.5 6 0 0 6 6 6 0 HAT (Half-A-TPR) repeat TPR_2 PF07719.17 OQS04742.1 - 1.5 9.1 16.4 2.7 8.3 0.0 5.3 6 0 0 6 6 6 0 Tetratricopeptide repeat CSN8_PSD8_EIF3K PF10075.9 OQS04743.1 - 2.8e-26 92.2 0.0 5.1e-26 91.4 0.0 1.4 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family SAC3_GANP PF03399.16 OQS04743.1 - 6.7e-06 25.7 0.4 9.8e-06 25.2 0.4 1.2 1 0 0 1 1 1 1 SAC3/GANP family adh_short PF00106.25 OQS04744.1 - 1.8e-43 148.3 1.3 3.7e-42 144.0 0.1 2.2 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 OQS04744.1 - 1.2e-24 87.2 0.6 2e-24 86.5 0.2 1.5 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OQS04744.1 - 1.9e-07 31.2 0.1 4.2e-07 30.1 0.1 1.5 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 OQS04744.1 - 0.0015 18.4 0.2 0.0043 17.0 0.2 1.7 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Epimerase PF01370.21 OQS04744.1 - 0.012 15.1 0.2 0.036 13.5 0.2 1.8 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family CdvA PF18822.1 OQS04744.1 - 0.032 14.1 1.5 0.32 10.8 0.0 2.7 3 0 0 3 3 3 0 CdvA-like coiled-coil domain NAD_binding_10 PF13460.6 OQS04744.1 - 0.11 12.3 0.1 0.26 11.2 0.1 1.7 1 0 0 1 1 1 0 NAD(P)H-binding Pox_A9 PF04835.12 OQS04745.1 - 0.064 13.4 0.1 0.084 13.0 0.1 1.2 1 0 0 1 1 1 0 A9 protein conserved region E_raikovi_mat PF06360.11 OQS04745.1 - 0.095 13.1 2.9 0.095 13.1 2.9 2.1 3 0 0 3 3 3 0 Euplotes raikovi mating pheromone TPD PF14811.6 OQS04746.1 - 1.6e-28 99.3 0.0 3.7e-28 98.1 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function TPD sequence-motif PPR_long PF17177.4 OQS04746.1 - 0.0088 15.4 0.0 0.027 13.8 0.0 1.9 2 0 0 2 2 2 1 Pentacotripeptide-repeat region of PRORP XendoU PF09412.10 OQS04747.1 - 2.3e-96 322.1 0.0 3.5e-96 321.5 0.0 1.2 1 0 0 1 1 1 1 Endoribonuclease XendoU EGF_2 PF07974.13 OQS04747.1 - 9.5e-09 35.5 68.1 1.7e-06 28.3 7.6 6.5 7 0 0 7 7 7 3 EGF-like domain Laminin_EGF PF00053.24 OQS04747.1 - 0.0026 17.9 35.9 0.027 14.6 5.5 3.7 3 0 0 3 3 3 2 Laminin EGF domain hEGF PF12661.7 OQS04747.1 - 0.021 15.5 5.8 0.021 15.5 5.8 5.2 4 0 0 4 4 4 0 Human growth factor-like EGF EGF PF00008.27 OQS04747.1 - 0.11 12.8 44.1 0.9 9.9 3.6 5.0 4 0 0 4 4 4 0 EGF-like domain IQ PF00612.27 OQS04747.1 - 0.14 12.0 0.2 0.33 10.9 0.2 1.6 1 0 0 1 1 1 0 IQ calmodulin-binding motif Nramp PF01566.18 OQS04749.1 - 6.6e-118 393.8 31.9 9.7e-118 393.2 31.9 1.2 1 0 0 1 1 1 1 Natural resistance-associated macrophage protein Baculo_PEP_C PF04513.12 OQS04750.1 - 0.017 15.2 24.3 0.026 14.5 0.5 5.0 3 2 1 5 5 5 0 Baculovirus polyhedron envelope protein, PEP, C terminus FBA PF04300.13 OQS04750.1 - 0.054 13.2 0.3 0.34 10.6 0.2 2.3 2 0 0 2 2 2 0 F-box associated region Apolipoprotein PF01442.18 OQS04750.1 - 0.12 12.3 30.3 0.41 10.5 3.0 4.5 2 1 1 3 3 3 0 Apolipoprotein A1/A4/E domain Bacillus_HBL PF05791.11 OQS04750.1 - 0.16 11.7 21.6 0.12 12.2 6.9 4.2 2 2 1 4 4 4 0 Bacillus haemolytic enterotoxin (HBL) DUF2130 PF09903.9 OQS04750.1 - 0.92 8.7 19.2 0.019 14.2 4.9 3.2 2 1 1 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2130) YtxH PF12732.7 OQS04750.1 - 3.3 8.3 10.3 14 6.3 1.7 4.5 3 2 0 3 3 3 0 YtxH-like protein DUF883 PF05957.13 OQS04750.1 - 3.5 8.3 12.7 6.8 7.4 0.1 4.5 3 1 0 4 4 4 0 Bacterial protein of unknown function (DUF883) zf-RING_2 PF13639.6 OQS04751.1 - 1.3e-12 47.9 9.9 1.3e-12 47.9 9.9 3.4 4 0 0 4 4 4 1 Ring finger domain FYVE PF01363.21 OQS04751.1 - 1.7e-11 44.1 12.8 1.7e-11 44.1 12.8 2.5 2 1 0 2 2 1 1 FYVE zinc finger zf-C3HC4_2 PF13923.6 OQS04751.1 - 1.4e-10 40.9 6.7 1.4e-10 40.9 6.7 3.8 3 1 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 OQS04751.1 - 9.8e-10 38.0 2.7 9.8e-10 38.0 2.7 3.1 4 0 0 4 4 2 1 RING-like zinc finger zf-rbx1 PF12678.7 OQS04751.1 - 3.8e-08 33.5 9.4 3.8e-08 33.5 9.4 4.0 2 2 1 3 3 2 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 OQS04751.1 - 5.4e-08 32.6 7.4 5.4e-08 32.6 7.4 3.4 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OQS04751.1 - 1.8e-07 31.0 3.0 1.8e-07 31.0 3.0 3.6 2 2 1 3 3 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 OQS04751.1 - 4.5e-07 29.7 4.5 4.5e-07 29.7 4.5 3.1 3 1 0 3 3 3 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 OQS04751.1 - 3.3e-05 23.6 6.2 3.3e-05 23.6 6.2 3.8 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 OQS04751.1 - 0.00057 19.9 6.7 0.00057 19.9 6.7 3.0 1 1 1 2 2 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_ribbon_17 PF17120.5 OQS04751.1 - 0.0084 15.7 7.8 0.0084 15.7 7.8 3.5 2 2 1 3 3 2 1 Zinc-ribbon, C4HC2 type zf-Nse PF11789.8 OQS04751.1 - 0.43 10.4 6.5 0.33 10.8 3.8 2.3 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit FYVE_2 PF02318.16 OQS04751.1 - 4.4 7.5 20.5 0.43 10.8 10.0 2.3 2 0 0 2 2 2 0 FYVE-type zinc finger zf-C3HC4_4 PF15227.6 OQS04751.1 - 6.4 7.0 30.6 0.12 12.5 9.3 4.5 3 1 1 4 4 4 0 zinc finger of C3HC4-type, RING Pkinase_Tyr PF07714.17 OQS04752.1 - 3.1e-77 259.4 0.0 3.6e-24 85.4 0.0 3.3 3 0 0 3 3 3 3 Protein tyrosine kinase Pkinase PF00069.25 OQS04752.1 - 3.4e-64 216.7 0.0 4e-20 72.3 0.1 3.2 3 0 0 3 3 3 3 Protein kinase domain EphA2_TM PF14575.6 OQS04752.1 - 0.00015 22.5 0.2 9.8 7.1 0.0 3.7 3 0 0 3 3 3 1 Ephrin type-A receptor 2 transmembrane domain Stevor PF17410.2 OQS04752.1 - 0.0016 18.0 0.1 6.5 6.2 0.0 3.4 3 0 0 3 3 3 1 Subtelomeric Variable Open Reading frame CD34_antigen PF06365.12 OQS04752.1 - 0.008 15.8 3.3 0.26 10.8 0.2 2.6 3 0 0 3 3 3 1 CD34/Podocalyxin family Syndecan PF01034.20 OQS04752.1 - 0.011 15.6 0.4 0.011 15.6 0.4 3.2 3 0 0 3 3 3 0 Syndecan domain DUF202 PF02656.15 OQS04752.1 - 0.013 15.9 4.0 9.5 6.8 0.1 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF202) DUF4381 PF14316.6 OQS04752.1 - 0.028 14.6 0.3 37 4.6 0.0 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4381) DUF4448 PF14610.6 OQS04752.1 - 0.036 13.8 0.1 0.29 10.9 0.1 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF4448) Adeno_E3_CR2 PF02439.15 OQS04752.1 - 0.044 13.5 11.7 6.6 6.6 0.0 3.4 3 0 0 3 3 3 0 Adenovirus E3 region protein CR2 Gram_pos_anchor PF00746.21 OQS04752.1 - 0.066 13.2 3.9 4.2 7.4 0.1 3.5 3 0 0 3 3 3 0 LPXTG cell wall anchor motif DUF4328 PF14219.6 OQS04752.1 - 0.091 12.3 1.1 1.3 8.5 0.2 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4328) DUF3290 PF11694.8 OQS04752.1 - 4 7.4 6.5 30 4.6 0.1 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3290) Autophagy_act_C PF03987.15 OQS04753.1 - 1.7e-18 66.9 0.4 3.5e-18 65.9 0.4 1.5 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain CCSAP PF15748.5 OQS04753.1 - 0.022 14.9 0.8 0.028 14.6 0.8 1.1 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated TRAP_alpha PF03896.16 OQS04753.1 - 0.071 12.3 0.9 0.082 12.1 0.9 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit RPA43_OB PF17875.1 OQS04753.1 - 1 10.0 4.3 1.7 9.3 4.2 1.5 1 1 0 1 1 1 0 RPA43 OB domain in RNA Pol I Phage_Gp23 PF10669.9 OQS04753.1 - 4.1 7.8 7.5 6.4 7.1 7.5 1.3 1 0 0 1 1 1 0 Protein gp23 (Bacteriophage A118) Sex_peptide PF08138.11 OQS04753.1 - 4.7 7.4 6.6 25 5.1 2.8 2.4 2 0 0 2 2 2 0 Sex peptide (SP) family DNA_pol_phi PF04931.13 OQS04753.1 - 8.4 4.4 11.9 11 3.9 11.9 1.1 1 0 0 1 1 1 0 DNA polymerase phi DUF1768 PF08719.11 OQS04754.1 - 7.5e-48 162.8 0.0 1.5e-47 161.8 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) zf-BED PF02892.15 OQS04754.1 - 0.021 14.8 4.6 0.058 13.4 4.6 1.8 1 0 0 1 1 1 0 BED zinc finger zf-C2HE PF16278.5 OQS04754.1 - 0.029 14.8 1.6 0.077 13.5 1.6 1.7 1 0 0 1 1 1 0 C2HE / C2H2 / C2HC zinc-binding finger KMP11 PF03037.16 OQS04755.1 - 0.22 12.3 1.9 1.7 9.5 0.2 2.4 2 0 0 2 2 2 0 Kinetoplastid membrane protein 11 DUF948 PF06103.11 OQS04755.1 - 0.65 10.3 3.5 1.5 9.2 3.4 1.7 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) DUF16 PF01519.16 OQS04755.1 - 0.76 10.3 4.7 2.7 8.5 4.7 2.0 1 1 0 1 1 1 0 Protein of unknown function DUF16 HeLo PF14479.6 OQS04755.1 - 1.3 8.9 6.5 11 5.8 6.3 2.1 1 1 0 1 1 1 0 Prion-inhibition and propagation Metallophos PF00149.28 OQS04757.1 - 1.4e-13 51.9 0.0 1.6e-13 51.6 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 OQS04757.1 - 1.1e-06 29.0 0.0 1.4e-06 28.6 0.0 1.3 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos_3 PF14582.6 OQS04757.1 - 0.0062 15.9 0.0 0.01 15.2 0.0 1.3 1 0 0 1 1 1 1 Metallophosphoesterase, calcineurin superfamily Acyl_transf_3 PF01757.22 OQS04760.1 - 3.4e-15 55.9 14.6 2.3e-14 53.2 10.2 2.5 2 1 1 3 3 3 2 Acyltransferase family MASE4 PF17158.4 OQS04760.1 - 0.045 13.0 0.1 0.045 13.0 0.1 2.2 2 0 0 2 2 2 0 Membrane-associated sensor, integral membrane domain YlaH PF14036.6 OQS04760.1 - 0.5 10.7 6.4 0.11 12.8 0.9 2.5 2 0 0 2 2 2 0 YlaH-like protein MerC PF03203.14 OQS04760.1 - 5.1 7.6 9.1 30 5.1 0.0 3.7 3 1 0 3 3 3 0 MerC mercury resistance protein Gsf2 PF11055.8 OQS04761.1 - 0.054 12.2 0.1 0.071 11.9 0.1 1.1 1 0 0 1 1 1 0 Glucose signalling factor 2 Acyl_transf_3 PF01757.22 OQS04762.1 - 3.5e-11 42.7 7.3 5.5e-11 42.1 7.3 1.4 1 0 0 1 1 1 1 Acyltransferase family TssN PF17555.2 OQS04762.1 - 0.94 8.8 4.5 1.3 8.4 4.5 1.1 1 0 0 1 1 1 0 Type VI secretion system, TssN 2-Hacid_dh_C PF02826.19 OQS04763.1 - 3.4e-45 153.6 0.0 1.2e-44 151.8 0.0 1.9 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 OQS04763.1 - 1.8e-28 98.9 0.0 3.4e-28 98.0 0.0 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain ACT PF01842.25 OQS04763.1 - 5.9e-06 25.9 0.0 2.1e-05 24.2 0.0 2.0 1 0 0 1 1 1 1 ACT domain Aminotran_5 PF00266.19 OQS04763.1 - 4e-05 22.8 0.0 7.3e-05 21.9 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V NAD_binding_2 PF03446.15 OQS04763.1 - 0.00031 20.9 0.0 0.00084 19.5 0.0 1.7 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase ACT_6 PF13740.6 OQS04763.1 - 0.024 14.6 0.0 0.12 12.4 0.0 2.2 2 0 0 2 2 2 0 ACT domain 3HCDH_N PF02737.18 OQS04763.1 - 0.027 14.4 0.0 0.05 13.5 0.0 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain IlvN PF07991.12 OQS04763.1 - 0.055 13.1 0.0 0.13 11.8 0.0 1.6 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain F420_oxidored PF03807.17 OQS04763.1 - 0.13 12.8 0.0 0.37 11.4 0.0 1.8 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Spem1 PF15670.5 OQS04764.1 - 5.5 6.5 10.0 12 5.4 10.0 1.5 1 0 0 1 1 1 0 Spermatid maturation protein 1 STT3 PF02516.14 OQS04765.1 - 4e-108 362.4 45.8 4.5e-107 359.0 45.8 1.9 1 1 0 1 1 1 1 Oligosaccharyl transferase STT3 subunit PDH_E1_M PF17831.1 OQS04765.1 - 2.1 7.8 4.5 1.8 8.0 3.1 1.6 1 1 0 1 1 1 0 Pyruvate dehydrogenase E1 component middle domain Proteasome PF00227.26 OQS04766.1 - 2.3e-62 209.9 0.2 3e-62 209.5 0.2 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 OQS04766.1 - 5.1e-15 54.8 0.1 9.9e-15 53.9 0.1 1.5 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature PP2C PF00481.21 OQS04768.1 - 4.2e-19 69.2 0.0 2.4e-10 40.5 0.0 2.4 2 0 0 2 2 2 2 Protein phosphatase 2C PP2C_2 PF13672.6 OQS04768.1 - 0.0051 16.5 0.0 0.11 12.1 0.0 2.3 2 0 0 2 2 2 1 Protein phosphatase 2C RCC1 PF00415.18 OQS04769.1 - 1.2e-65 217.9 11.5 7.7e-14 52.0 0.3 7.7 6 1 1 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 OQS04769.1 - 2.1e-23 81.5 45.2 3e-07 30.0 1.2 8.2 8 0 0 8 8 8 4 Regulator of chromosome condensation (RCC1) repeat PA PF02225.22 OQS04769.1 - 3.2e-08 33.5 0.0 0.00021 21.3 0.0 2.9 3 0 0 3 3 3 2 PA domain EF-hand_6 PF13405.6 OQS04769.1 - 0.00027 20.6 0.3 0.0012 18.6 0.2 2.1 2 0 0 2 2 2 1 EF-hand domain EF-hand_1 PF00036.32 OQS04769.1 - 0.0011 18.4 0.2 0.003 17.0 0.2 1.8 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.6 OQS04769.1 - 0.0023 18.3 0.1 0.01 16.3 0.1 2.1 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_8 PF13833.6 OQS04769.1 - 0.026 14.4 0.2 0.066 13.1 0.2 1.6 1 0 0 1 1 1 0 EF-hand domain pair EF-hand_5 PF13202.6 OQS04769.1 - 0.097 12.2 0.5 0.22 11.1 0.5 1.6 1 0 0 1 1 1 0 EF hand IQ PF00612.27 OQS04769.1 - 0.1 12.4 0.1 0.29 11.0 0.1 1.7 1 0 0 1 1 1 0 IQ calmodulin-binding motif Mg_trans_NIPA PF05653.14 OQS04770.1 - 0.049 12.7 0.9 0.066 12.3 0.9 1.2 1 0 0 1 1 1 0 Magnesium transporter NIPA Cut8 PF08559.10 OQS04770.1 - 0.21 11.2 0.2 0.25 10.9 0.2 1.1 1 0 0 1 1 1 0 Cut8, nuclear proteasome tether protein ATHILA PF03078.15 OQS04771.1 - 0.038 12.8 0.0 0.06 12.2 0.0 1.3 1 0 0 1 1 1 0 ATHILA ORF-1 family Il2rg PF15874.5 OQS04771.1 - 0.064 13.5 0.2 0.63 10.3 0.0 2.1 2 0 0 2 2 2 0 Putative Interleukin 2 receptor, gamma chain FAT PF02259.23 OQS04773.1 - 3.6e-82 276.4 1.8 4.8e-82 275.9 1.8 1.2 1 0 0 1 1 1 1 FAT domain PI3_PI4_kinase PF00454.27 OQS04773.1 - 6.9e-47 160.4 0.0 1.3e-46 159.4 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FRB_dom PF08771.11 OQS04773.1 - 5.9e-41 138.9 0.2 2.9e-40 136.7 0.1 2.2 2 0 0 2 2 2 1 FKBP12-rapamycin binding domain Nipped-B_C PF12830.7 OQS04773.1 - 0.022 14.7 0.0 0.048 13.6 0.0 1.5 1 0 0 1 1 1 0 Sister chromatid cohesion C-terminus Ion_trans PF00520.31 OQS04774.1 - 8.7e-164 542.6 91.2 1.5e-47 161.9 8.3 4.2 4 0 0 4 4 4 4 Ion transport protein Tim17 PF02466.19 OQS04774.1 - 2.5e-19 69.7 6.8 8.3e-19 68.0 6.8 2.0 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family GPHH PF16905.5 OQS04774.1 - 6.7e-07 29.0 0.0 1.7e-06 27.7 0.0 1.7 1 0 0 1 1 1 1 Voltage-dependent L-type calcium channel, IQ-associated PKD_channel PF08016.12 OQS04774.1 - 4.7e-05 22.3 88.4 0.0034 16.1 1.4 11.1 8 3 3 11 11 11 9 Polycystin cation channel Ion_trans PF00520.31 OQS04775.1 - 3.3e-158 524.3 77.1 1e-40 139.6 18.6 5.3 4 1 0 4 4 4 4 Ion transport protein PKD_channel PF08016.12 OQS04775.1 - 0.0049 15.6 71.5 0.028 13.1 1.0 10.4 8 3 2 10 10 10 9 Polycystin cation channel IKI3 PF04762.12 OQS04776.1 - 3.6e-151 505.2 14.5 9.2e-82 275.5 0.6 3.1 2 1 1 3 3 3 3 IKI3 family ANAPC4_WD40 PF12894.7 OQS04776.1 - 1.6e-05 25.1 2.0 0.026 14.8 0.1 3.2 2 0 0 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain Mre11_DNA_bind PF04152.14 OQS04777.1 - 2e-42 145.4 0.2 2e-42 145.4 0.2 2.6 3 0 0 3 3 3 1 Mre11 DNA-binding presumed domain Metallophos PF00149.28 OQS04777.1 - 1.8e-16 61.2 0.3 2.7e-16 60.7 0.3 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 OQS04777.1 - 6.8e-05 23.1 0.0 0.00069 19.8 0.0 2.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain TNV_CP PF03898.13 OQS04777.1 - 0.25 10.6 4.0 0.15 11.3 1.6 1.7 2 0 0 2 2 2 0 Satellite tobacco necrosis virus coat protein DUF572 PF04502.13 OQS04777.1 - 9.3 5.8 18.3 4.6 6.8 16.3 1.4 2 0 0 2 2 2 0 Family of unknown function (DUF572) DUF3130 PF11328.8 OQS04778.1 - 0.029 14.6 0.1 0.069 13.4 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3130 SAC3_GANP PF03399.16 OQS04779.1 - 4e-88 295.6 0.0 9.7e-88 294.3 0.0 1.7 1 0 0 1 1 1 1 SAC3/GANP family CSN8_PSD8_EIF3K PF10075.9 OQS04779.1 - 1.2e-05 25.4 0.0 3.6e-05 23.8 0.0 1.9 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family KIAA1430 PF13879.6 OQS04779.1 - 0.008 16.9 0.5 0.008 16.9 0.5 2.9 1 1 1 2 2 2 1 KIAA1430 homologue Peptidase_M17 PF00883.21 OQS04780.1 - 4.2e-110 367.9 0.1 5.4e-110 367.5 0.1 1.1 1 0 0 1 1 1 1 Cytosol aminopeptidase family, catalytic domain Peptidase_M17_N PF02789.17 OQS04780.1 - 2.3e-10 40.4 0.0 6.4e-10 39.0 0.0 1.8 1 0 0 1 1 1 1 Cytosol aminopeptidase family, N-terminal domain DUF818 PF05677.12 OQS04780.1 - 0.12 11.3 0.0 0.2 10.6 0.0 1.2 1 0 0 1 1 1 0 Chlamydia CHLPS protein (DUF818) PT PF04886.12 OQS04781.1 - 0.0033 16.9 20.4 0.0033 16.9 20.4 3.8 2 2 1 3 3 3 2 PT repeat HSF_DNA-bind PF00447.17 OQS04782.1 - 1.1e-25 90.1 2.6 1.8e-25 89.4 2.6 1.3 1 0 0 1 1 1 1 HSF-type DNA-binding DNA_pol_B_exo2 PF10108.9 OQS04782.1 - 0.008 15.9 0.1 0.014 15.1 0.1 1.3 1 0 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB IL28A PF15177.6 OQS04783.1 - 0.023 14.6 0.0 0.029 14.2 0.0 1.1 1 0 0 1 1 1 0 Interleukin-28A UB2H PF14814.6 OQS04783.1 - 0.035 14.1 0.2 0.063 13.3 0.2 1.3 1 0 0 1 1 1 0 Bifunctional transglycosylase second domain Metallophos PF00149.28 OQS04784.1 - 5.1e-27 95.7 0.4 6e-27 95.5 0.4 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Glyco_hydro_65N PF03636.15 OQS04784.1 - 0.015 14.9 0.0 0.021 14.5 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 65, N-terminal domain STPPase_N PF16891.5 OQS04784.1 - 0.02 15.3 0.0 0.039 14.4 0.0 1.5 1 0 0 1 1 1 0 Serine-threonine protein phosphatase N-terminal domain Metallophos PF00149.28 OQS04785.1 - 0.015 15.8 0.0 0.022 15.3 0.0 1.3 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase Ank_2 PF12796.7 OQS04786.1 - 7.7e-07 29.6 0.1 1.5e-06 28.7 0.1 1.5 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQS04786.1 - 4.3e-05 24.0 0.0 8.4e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 OQS04786.1 - 0.00062 20.0 0.0 0.27 11.6 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQS04786.1 - 0.006 17.0 0.0 5.4 7.9 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeat DUF4647 PF15504.6 OQS04786.1 - 0.11 11.6 7.5 0.14 11.2 7.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4647) DUF3959 PF13105.6 OQS04786.1 - 9 5.7 7.4 12 5.3 7.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3959) Metallophos PF00149.28 OQS04787.1 - 3.9e-35 122.2 0.9 5.1e-35 121.8 0.9 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Glyco_hydro_65N PF03636.15 OQS04787.1 - 0.0055 16.4 0.0 0.0081 15.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, N-terminal domain STPPase_N PF16891.5 OQS04787.1 - 0.043 14.3 0.0 0.082 13.4 0.0 1.4 1 0 0 1 1 1 0 Serine-threonine protein phosphatase N-terminal domain Pkinase_Tyr PF07714.17 OQS04788.1 - 2.1e-29 102.6 0.0 2.8e-29 102.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OQS04788.1 - 6.4e-29 101.1 0.0 1.1e-28 100.3 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Peptidase_C69 PF03577.15 OQS04790.1 - 3e-44 151.6 0.4 2e-43 148.9 0.4 2.2 1 1 0 1 1 1 1 Peptidase family C69 DUF4619 PF15398.6 OQS04792.1 - 0.0042 16.6 0.5 0.0048 16.5 0.5 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4619) MORN PF02493.20 OQS04793.1 - 5.2e-74 239.9 119.8 8.1e-07 28.6 1.8 19.4 20 0 0 20 20 20 18 MORN repeat GST_N PF02798.20 OQS04794.1 - 4.6e-18 65.3 0.0 7.4e-18 64.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 OQS04794.1 - 2.7e-17 63.0 0.1 5.5e-17 62.0 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 OQS04794.1 - 6.9e-15 55.1 0.0 1.2e-14 54.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 OQS04794.1 - 1e-08 35.3 0.0 1.7e-08 34.5 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 OQS04794.1 - 3.6e-06 27.1 0.0 5.9e-06 26.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 OQS04794.1 - 0.0091 16.0 0.0 0.018 15.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain HTH_25 PF13413.6 OQS04794.1 - 0.11 12.3 0.0 0.23 11.4 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain TUG-UBL1 PF11470.8 OQS04795.1 - 1.8e-19 69.7 0.0 8.8e-19 67.5 0.0 2.3 2 0 0 2 2 2 1 TUG ubiquitin-like domain PUB PF09409.10 OQS04795.1 - 9.7e-14 51.1 0.1 4.3e-13 49.0 0.0 1.9 1 1 1 2 2 2 1 PUB domain UBX PF00789.20 OQS04795.1 - 9e-11 41.8 0.2 4.4e-06 26.8 0.1 2.7 2 0 0 2 2 2 2 UBX domain RBD PF02196.15 OQS04795.1 - 0.0088 16.1 0.1 0.098 12.7 0.0 2.6 3 0 0 3 3 3 1 Raf-like Ras-binding domain CIDE-N PF02017.15 OQS04795.1 - 0.022 14.8 0.0 1 9.5 0.0 2.8 2 0 0 2 2 2 0 CIDE-N domain LRR_6 PF13516.6 OQS04796.1 - 6.9e-39 128.6 55.0 1.2e-06 28.1 0.1 14.9 17 0 0 17 17 17 10 Leucine Rich repeat LRR_4 PF12799.7 OQS04796.1 - 8.6e-18 64.1 30.9 0.00038 20.8 0.4 9.0 5 4 4 9 9 9 8 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 OQS04796.1 - 4.9e-14 51.8 35.6 3.5e-07 29.9 3.5 8.7 5 4 2 7 7 7 5 Leucine rich repeat LRR_1 PF00560.33 OQS04796.1 - 1.1e-08 34.5 23.5 2.2 9.2 0.1 12.4 13 1 0 13 13 13 2 Leucine Rich Repeat AMP-binding PF00501.28 OQS04797.1 - 8.2e-22 77.4 2.1 2.9e-21 75.6 0.2 2.0 2 0 0 2 2 2 1 AMP-binding enzyme AMP-binding_C PF13193.6 OQS04797.1 - 0.11 13.5 0.0 0.34 11.9 0.0 1.9 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain E1-E2_ATPase PF00122.20 OQS04799.1 - 1.7e-49 167.8 0.7 1.7e-49 167.8 0.7 3.2 3 0 0 3 3 3 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 OQS04799.1 - 2.8e-34 118.4 14.6 1.1e-16 61.0 0.0 3.7 3 1 0 3 3 3 2 Cation transporting ATPase, C-terminus Cation_ATPase PF13246.6 OQS04799.1 - 6.8e-23 80.6 0.5 2.4e-22 78.8 0.1 2.1 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 OQS04799.1 - 2.4e-20 73.7 0.0 3.3e-10 40.6 0.0 3.4 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 OQS04799.1 - 2.2e-13 49.7 0.0 4.4e-13 48.7 0.0 1.5 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 OQS04799.1 - 2.5e-05 24.2 3.2 0.004 16.9 0.4 3.0 3 0 0 3 3 3 2 haloacid dehalogenase-like hydrolase ALG11_N PF15924.5 OQS04800.1 - 6.2e-75 251.8 1.0 8.3e-75 251.4 1.0 1.2 1 0 0 1 1 1 1 ALG11 mannosyltransferase N-terminus Glycos_transf_1 PF00534.20 OQS04800.1 - 5e-29 101.0 0.0 7.2e-29 100.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 OQS04800.1 - 8.3e-15 55.4 0.0 1.5e-14 54.5 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 FHA PF00498.26 OQS04801.1 - 1.9e-24 85.8 1.2 2.2e-11 44.0 0.1 2.3 2 0 0 2 2 2 2 FHA domain Yop-YscD_cpl PF16697.5 OQS04801.1 - 4.8e-17 62.0 0.0 1e-10 41.8 0.0 3.2 2 1 0 2 2 2 2 Inner membrane component of T3SS, cytoplasmic domain MMR_HSR1_Xtn PF16897.5 OQS04802.1 - 1.7e-39 134.1 0.0 3.7e-39 133.0 0.0 1.6 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain MMR_HSR1 PF01926.23 OQS04802.1 - 6e-20 71.4 0.1 2e-19 69.8 0.0 1.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase TGS PF02824.21 OQS04802.1 - 1.9e-17 63.1 0.0 3.8e-17 62.1 0.0 1.6 1 0 0 1 1 1 1 TGS domain FeoB_N PF02421.18 OQS04802.1 - 7.6e-09 35.3 0.0 1.4e-08 34.4 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 OQS04802.1 - 0.00031 20.8 1.8 0.12 12.4 0.0 2.9 3 0 0 3 3 3 2 Dynamin family AAA_28 PF13521.6 OQS04802.1 - 0.015 15.5 0.1 0.052 13.8 0.1 1.9 2 0 0 2 2 2 0 AAA domain Roc PF08477.13 OQS04802.1 - 0.025 14.8 0.6 0.21 11.8 0.0 2.6 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OQS04802.1 - 0.035 13.6 0.2 0.12 11.8 0.0 1.9 2 0 0 2 2 2 0 ADP-ribosylation factor family AAA_16 PF13191.6 OQS04802.1 - 0.05 14.0 0.0 0.091 13.1 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 OQS04802.1 - 0.13 12.6 0.0 0.39 11.0 0.0 1.8 2 0 0 2 2 2 0 AAA domain Ank_2 PF12796.7 OQS04804.1 - 9.2e-39 131.9 17.9 1e-11 45.3 0.6 4.8 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQS04804.1 - 2e-30 104.7 18.9 2.9e-06 27.7 1.0 8.3 4 1 5 9 9 9 9 Ankyrin repeats (many copies) Ank_5 PF13857.6 OQS04804.1 - 3.1e-26 91.1 17.7 1.3e-06 28.6 0.2 6.8 3 1 4 7 7 7 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQS04804.1 - 4.5e-25 85.0 14.2 0.00028 21.1 0.2 9.2 9 0 0 9 9 9 7 Ankyrin repeat Ank PF00023.30 OQS04804.1 - 2.7e-18 65.5 18.8 5.4e-05 23.5 0.1 9.0 8 1 0 8 8 8 5 Ankyrin repeat Ank_2 PF12796.7 OQS04805.1 - 4e-30 104.2 9.2 1.7e-12 47.7 0.2 3.0 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQS04805.1 - 4.9e-27 93.9 9.3 9e-11 42.1 0.1 4.6 2 2 3 5 5 5 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 OQS04805.1 - 3.4e-24 84.6 5.9 3.5e-07 30.4 0.1 4.9 2 2 3 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQS04805.1 - 6.6e-23 78.3 4.6 0.0011 19.2 0.0 6.3 6 0 0 6 6 6 4 Ankyrin repeat Ank PF00023.30 OQS04805.1 - 5.2e-17 61.4 10.2 0.0004 20.7 0.1 5.8 6 0 0 6 6 6 4 Ankyrin repeat DUF3447 PF11929.8 OQS04805.1 - 0.00042 20.2 0.3 3.9 7.5 0.0 3.8 2 2 0 2 2 2 2 Domain of unknown function (DUF3447) Palm_thioest PF02089.15 OQS04806.1 - 3.9e-62 210.3 0.0 7.2e-62 209.4 0.0 1.4 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Cellulase PF00150.18 OQS04806.1 - 1.1e-25 90.7 5.7 2e-25 89.8 5.7 1.5 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Abhydrolase_6 PF12697.7 OQS04806.1 - 0.0097 16.5 0.2 0.75 10.4 0.0 2.9 2 1 0 2 2 2 1 Alpha/beta hydrolase family DUF676 PF05057.14 OQS04806.1 - 0.03 13.8 0.0 0.054 13.0 0.0 1.3 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Hydrolase_4 PF12146.8 OQS04806.1 - 0.03 13.6 0.0 0.27 10.5 0.0 2.3 3 0 0 3 3 3 0 Serine aminopeptidase, S33 Palm_thioest PF02089.15 OQS04807.1 - 3.3e-74 249.8 0.0 4e-74 249.5 0.0 1.1 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Hydrolase_4 PF12146.8 OQS04807.1 - 0.0031 16.8 0.0 0.0052 16.1 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Lipase_2 PF01674.18 OQS04807.1 - 0.013 15.1 0.0 0.11 12.0 0.0 2.2 1 1 0 1 1 1 0 Lipase (class 2) Abhydrolase_1 PF00561.20 OQS04807.1 - 0.018 14.7 0.1 0.034 13.8 0.1 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold Glyco_trans_4_5 PF16994.5 OQS04808.1 - 0.066 12.8 0.1 0.13 11.9 0.1 1.4 1 1 0 1 1 1 0 Glycosyl-transferase family 4 Utp13 PF08625.11 OQS04808.1 - 0.19 11.6 1.0 1.6 8.6 1.0 2.2 1 1 0 1 1 1 0 Utp13 specific WD40 associated domain DEAD PF00270.29 OQS04809.1 - 6.2e-18 65.2 0.0 1e-17 64.5 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase RecQ_Zn_bind PF16124.5 OQS04809.1 - 7.3e-16 58.7 4.4 1.8e-15 57.4 4.4 1.7 1 0 0 1 1 1 1 RecQ zinc-binding Helicase_C PF00271.31 OQS04809.1 - 2e-14 53.9 0.0 1.5e-13 51.1 0.0 2.4 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 OQS04809.1 - 0.04 13.9 0.0 0.31 11.0 0.0 2.2 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit Got1 PF04178.12 OQS04810.1 - 1.2e-25 90.2 15.6 1.5e-25 89.8 15.6 1.2 1 0 0 1 1 1 1 Got1/Sft2-like family EI24 PF07264.11 OQS04810.1 - 2 8.6 14.2 2.8 8.2 14.2 1.1 1 0 0 1 1 1 0 Etoposide-induced protein 2.4 (EI24) DUF4538 PF15061.6 OQS04810.1 - 2.2 8.1 4.4 6.3 6.6 0.4 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4538) Phage_holin_3_6 PF07332.11 OQS04810.1 - 3.3 7.8 11.0 2.3 8.3 0.9 2.1 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III DUF3099 PF11298.8 OQS04810.1 - 5.6 7.2 6.4 11 6.3 0.1 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3099) HMG_box PF00505.19 OQS04811.1 - 4.3e-19 68.7 1.4 9.5e-19 67.6 1.4 1.5 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 OQS04811.1 - 1.7e-13 51.0 2.4 1.7e-13 51.0 2.4 2.2 2 1 0 2 2 2 1 HMG-box domain YABBY PF04690.13 OQS04811.1 - 0.0038 17.8 1.2 0.0038 17.8 1.2 1.4 1 1 0 1 1 1 1 YABBY protein LRR_6 PF13516.6 OQS04812.1 - 0.00045 20.1 11.8 0.18 11.9 0.1 5.9 6 0 0 6 6 6 2 Leucine Rich repeat CAMSAP_CC1 PF17095.5 OQS04812.1 - 0.11 12.4 3.1 0.27 11.1 3.1 1.7 1 0 0 1 1 1 0 Spectrin-binding region of Ca2+-Calmodulin LRR_1 PF00560.33 OQS04812.1 - 0.16 12.6 3.1 52 5.0 0.5 4.5 3 1 0 3 3 3 0 Leucine Rich Repeat Ntox5 PF15543.6 OQS04812.1 - 0.17 11.8 0.0 0.37 10.6 0.0 1.5 1 0 0 1 1 1 0 Bacterial toxin 5 LRR_8 PF13855.6 OQS04812.1 - 1.1 9.1 17.4 17 5.3 0.0 5.8 2 2 3 5 5 5 0 Leucine rich repeat LRR_4 PF12799.7 OQS04812.1 - 8.8 6.9 20.4 15 6.2 0.0 5.9 3 2 2 5 5 5 0 Leucine Rich repeats (2 copies) WD40 PF00400.32 OQS04813.1 - 1.6e-12 47.7 8.9 0.076 13.9 0.1 6.3 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OQS04813.1 - 6.7e-06 26.3 0.3 0.92 9.9 0.0 4.4 2 2 2 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain FdtA PF05523.11 OQS04813.1 - 0.0013 18.4 0.0 0.0029 17.3 0.0 1.7 1 0 0 1 1 1 1 WxcM-like, C-terminal ZapB PF06005.12 OQS04813.1 - 0.036 14.5 1.6 0.071 13.6 1.6 1.4 1 0 0 1 1 1 0 Cell division protein ZapB CODH_A_N PF18537.1 OQS04813.1 - 0.057 13.4 0.2 0.13 12.2 0.2 1.6 1 0 0 1 1 1 0 Carbon monoxide dehydrogenase subunit alpha N-terminal domain HALZ PF02183.18 OQS04813.1 - 0.09 13.0 3.7 0.25 11.6 3.7 1.8 1 0 0 1 1 1 0 Homeobox associated leucine zipper NRBF2 PF08961.10 OQS04813.1 - 0.096 12.3 0.6 0.16 11.6 0.6 1.2 1 0 0 1 1 1 0 Nuclear receptor-binding factor 2, autophagy regulator bZIP_1 PF00170.21 OQS04813.1 - 1.3 9.2 3.9 2.4 8.3 3.9 1.4 1 0 0 1 1 1 0 bZIP transcription factor zf-C2HC_2 PF13913.6 OQS04814.1 - 3.3e-15 55.5 5.9 8.2e-09 35.2 0.6 2.5 2 0 0 2 2 2 2 zinc-finger of a C2HC-type Rhodanese_C PF12368.8 OQS04814.1 - 0.023 15.1 0.7 3.7 8.0 0.0 2.3 2 0 0 2 2 2 0 Rhodanase C-terminal T3SS_needle_F PF09392.10 OQS04814.1 - 0.039 14.2 0.0 0.08 13.2 0.0 1.5 1 0 0 1 1 1 0 Type III secretion needle MxiH, YscF, SsaG, EprI, PscF, EscF SOG2 PF10428.9 OQS04814.1 - 0.077 12.2 15.0 0.092 11.9 15.0 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein DUF1178 PF06676.11 OQS04814.1 - 0.12 12.7 0.4 0.33 11.3 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1178) FYVE PF01363.21 OQS04814.1 - 0.17 12.0 1.1 24 5.2 0.7 2.4 2 0 0 2 2 2 0 FYVE zinc finger SBP PF03110.14 OQS04814.1 - 0.71 10.2 5.4 0.17 12.2 0.6 2.1 2 0 0 2 2 2 0 SBP domain Rad50_zn_hook PF04423.14 OQS04814.1 - 0.88 9.5 3.2 14 5.6 0.8 2.4 2 0 0 2 2 2 0 Rad50 zinc hook motif zf-C2H2 PF00096.26 OQS04814.1 - 1.2 9.7 4.8 6.5 7.4 0.1 2.8 3 0 0 3 3 2 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 OQS04814.1 - 1.6 9.8 6.7 12 7.0 0.1 3.0 3 0 0 3 3 3 0 C2H2-type zinc finger DUF2256 PF10013.9 OQS04814.1 - 6.1 7.0 6.1 29 4.9 0.2 2.9 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2256) Blo-t-5 PF11642.8 OQS04815.1 - 0.015 15.3 0.0 0.033 14.2 0.0 1.5 1 1 0 1 1 1 0 Mite allergen Blo t 5 Ank_4 PF13637.6 OQS04816.1 - 4.3e-12 46.3 0.6 3.7e-07 30.6 0.2 3.7 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 OQS04816.1 - 2.7e-11 43.9 0.1 5.4e-09 36.5 0.0 3.6 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OQS04816.1 - 1.8e-07 31.3 0.1 6.8e-05 23.1 0.0 3.7 2 1 2 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQS04816.1 - 1.4e-06 28.2 3.2 0.0063 16.9 0.0 4.8 5 0 0 5 5 5 1 Ankyrin repeat Ank PF00023.30 OQS04816.1 - 1.9e-06 28.1 0.4 0.13 12.8 0.0 4.8 5 0 0 5 5 5 1 Ankyrin repeat WW PF00397.26 OQS04816.1 - 6.1e-06 26.2 0.1 1.9e-05 24.6 0.1 1.9 1 0 0 1 1 1 1 WW domain IQ PF00612.27 OQS04816.1 - 0.0018 17.9 0.7 0.011 15.5 0.7 2.5 1 0 0 1 1 1 1 IQ calmodulin-binding motif BAH PF01426.18 OQS04817.1 - 6.2e-05 22.8 0.0 0.00028 20.7 0.0 2.1 2 1 0 2 2 2 1 BAH domain ELM2 PF01448.24 OQS04817.1 - 0.00044 20.9 0.0 0.0012 19.6 0.0 1.8 1 0 0 1 1 1 1 ELM2 domain DUF1571 PF07608.11 OQS04817.1 - 0.058 12.8 1.3 0.079 12.4 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1571) Ribosomal_L27A PF00828.19 OQS04819.1 - 1.7e-23 83.7 0.2 2.4e-23 83.2 0.1 1.3 1 1 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A DUF4988 PF16378.5 OQS04819.1 - 0.16 11.7 0.0 0.2 11.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function DUF333 PF03891.15 OQS04821.1 - 0.0018 18.5 0.2 9.1 6.6 0.0 4.4 4 0 0 4 4 4 2 Domain of unknown function (DUF333) Tachystatin_A PF11406.8 OQS04821.1 - 1.4 9.1 6.5 36 4.5 0.2 3.7 3 0 0 3 3 3 0 Antimicrobial peptide tachystatin A ECD PF18432.1 OQS04822.1 - 0.044 13.7 0.0 0.065 13.2 0.0 1.3 1 0 0 1 1 1 0 Extracellular Cadherin domain F-box-like PF12937.7 OQS04823.1 - 0.00063 19.6 3.9 0.0041 17.0 1.0 3.1 2 0 0 2 2 2 1 F-box-like SAM_PNT PF02198.16 OQS04823.1 - 0.081 12.9 0.7 0.46 10.5 0.0 2.5 3 0 0 3 3 3 0 Sterile alpha motif (SAM)/Pointed domain zf-FCS PF06467.14 OQS04823.1 - 1.1 9.3 6.7 4.6 7.3 6.7 2.2 1 1 0 1 1 1 0 MYM-type Zinc finger with FCS sequence motif zf-MYND PF01753.18 OQS04823.1 - 3.5 7.8 6.8 14 5.9 6.8 2.1 1 0 0 1 1 1 0 MYND finger PTH2 PF01981.16 OQS04825.1 - 6.2e-46 155.5 1.5 7.1e-46 155.3 0.5 1.5 2 0 0 2 2 2 1 Peptidyl-tRNA hydrolase PTH2 AsnC_trans_reg PF01037.21 OQS04825.1 - 0.1 12.6 0.0 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 Lrp/AsnC ligand binding domain DUF3006 PF11213.8 OQS04826.1 - 0.075 13.3 0.5 0.13 12.5 0.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3006) SUIM_assoc PF16619.5 OQS04826.1 - 0.21 11.7 0.5 0.21 11.7 0.5 2.0 2 1 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 RTC PF01137.21 OQS04827.1 - 1.2e-59 201.2 0.3 1.9e-59 200.6 0.3 1.3 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase TatD_DNase PF01026.21 OQS04827.1 - 4e-43 147.6 0.0 5.7e-43 147.1 0.0 1.2 1 0 0 1 1 1 1 TatD related DNase VPS13 PF16908.5 OQS04828.1 - 3.9e-63 213.4 1.7 1.5e-62 211.5 1.1 2.4 2 0 0 2 2 2 1 Vacuolar sorting-associated protein 13, N-terminal VPS13_C PF16909.5 OQS04828.1 - 2.8e-37 128.2 0.0 2.4e-34 118.7 0.0 3.4 3 0 0 3 3 3 2 Vacuolar-sorting-associated 13 protein C-terminal SHR-BD PF06650.12 OQS04828.1 - 4.9e-34 117.9 0.0 3.8e-27 95.3 0.0 3.7 4 0 0 4 4 4 2 SHR-binding domain of vacuolar-sorting associated protein 13 VPS13_mid_rpt PF16910.5 OQS04828.1 - 7.1e-34 117.3 2.7 1e-30 106.9 0.0 4.3 4 0 0 4 4 4 2 Repeating coiled region of VPS13 Chorein_N PF12624.7 OQS04828.1 - 5.9e-21 74.7 0.3 3.3e-20 72.3 0.0 2.5 2 0 0 2 2 2 1 N-terminal region of Chorein or VPS13 ATG_C PF09333.11 OQS04828.1 - 0.095 13.1 0.0 0.41 11.0 0.0 2.1 1 0 0 1 1 1 0 Autophagy-related protein C terminal domain WD40 PF00400.32 OQS04829.1 - 1.5e-21 76.3 3.6 5.2e-08 33.4 0.1 6.1 6 0 0 6 6 6 4 WD domain, G-beta repeat Striatin PF08232.12 OQS04829.1 - 2.1e-13 51.1 2.0 3e-13 50.7 2.0 1.2 1 0 0 1 1 1 1 Striatin family Nucleoporin_N PF08801.11 OQS04829.1 - 1.4e-06 27.4 0.0 0.04 12.7 0.0 3.2 3 0 0 3 3 3 3 Nup133 N terminal like ANAPC4_WD40 PF12894.7 OQS04829.1 - 3.6e-05 24.0 0.2 0.76 10.1 0.0 3.6 4 1 1 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Ion_trans PF00520.31 OQS04830.1 - 3.4e-18 65.8 9.9 3.4e-18 65.8 9.9 1.8 2 0 0 2 2 2 1 Ion transport protein BK_channel_a PF03493.18 OQS04830.1 - 5.6e-17 61.7 0.2 1.6e-15 57.1 0.1 2.6 2 0 0 2 2 2 1 Calcium-activated BK potassium channel alpha subunit Ion_trans_2 PF07885.16 OQS04830.1 - 8.1e-11 41.7 0.4 8.1e-11 41.7 0.4 2.4 2 0 0 2 2 2 1 Ion channel TrkA_C PF02080.21 OQS04830.1 - 0.00031 20.5 0.0 0.00096 18.9 0.0 1.9 1 0 0 1 1 1 1 TrkA-C domain Castor_Poll_mid PF06241.12 OQS04830.1 - 0.00096 19.1 0.0 0.004 17.1 0.0 2.1 2 0 0 2 2 2 1 Castor and Pollux, part of voltage-gated ion channel WW PF00397.26 OQS04831.1 - 1.1e-12 47.7 20.3 1.4e-06 28.3 6.2 2.7 3 0 0 3 3 2 2 WW domain EF-hand_1 PF00036.32 OQS04831.1 - 4e-10 38.5 0.3 4.4e-06 25.9 0.2 2.8 2 0 0 2 2 2 2 EF hand LRR_8 PF13855.6 OQS04831.1 - 6.3e-09 35.5 0.3 1.1e-08 34.7 0.3 1.4 1 0 0 1 1 1 1 Leucine rich repeat EF-hand_6 PF13405.6 OQS04831.1 - 1e-08 34.4 0.3 4.1e-05 23.2 0.1 3.2 3 0 0 3 3 3 2 EF-hand domain EF-hand_7 PF13499.6 OQS04831.1 - 1.7e-08 34.8 0.1 5.1e-08 33.3 0.1 1.8 1 0 0 1 1 1 1 EF-hand domain pair LRR_4 PF12799.7 OQS04831.1 - 0.0017 18.7 0.1 0.0046 17.3 0.1 1.7 1 0 0 1 1 1 1 Leucine Rich repeats (2 copies) IQ PF00612.27 OQS04831.1 - 0.0026 17.4 4.4 0.0062 16.2 4.4 1.7 1 0 0 1 1 1 1 IQ calmodulin-binding motif EF-hand_8 PF13833.6 OQS04831.1 - 0.0036 17.1 0.3 0.14 12.0 0.0 2.8 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.6 OQS04831.1 - 0.0053 16.2 0.5 0.027 13.9 0.1 2.5 3 0 0 3 3 3 1 EF hand PQQ PF01011.21 OQS04831.1 - 0.056 13.4 1.6 0.27 11.3 0.2 2.7 3 0 0 3 3 3 0 PQQ enzyme repeat LRR_1 PF00560.33 OQS04831.1 - 0.15 12.7 1.0 38 5.4 0.0 3.1 2 1 0 2 2 2 0 Leucine Rich Repeat Gar1 PF04410.14 OQS04832.1 - 9.1e-35 119.7 0.0 9.1e-35 119.7 0.0 2.2 2 1 1 3 3 3 1 Gar1/Naf1 RNA binding region Presenilin PF01080.17 OQS04832.1 - 5 5.8 12.8 0.29 9.8 1.1 2.1 2 0 0 2 2 2 0 Presenilin ERCC4 PF02732.15 OQS04833.1 - 5.7e-21 75.3 0.1 1.7e-20 73.8 0.0 1.9 2 0 0 2 2 2 1 ERCC4 domain HHH_2 PF12826.7 OQS04833.1 - 0.045 13.9 0.0 0.13 12.4 0.0 1.8 1 0 0 1 1 1 0 Helix-hairpin-helix motif LRR_8 PF13855.6 OQS04834.1 - 1.6e-43 146.3 62.0 1.9e-10 40.3 6.0 10.0 6 2 5 11 11 11 9 Leucine rich repeat LRR_4 PF12799.7 OQS04834.1 - 4.9e-36 122.2 65.7 3.1e-07 30.6 2.2 11.2 9 2 1 11 11 11 9 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 OQS04834.1 - 1.7e-09 37.5 30.3 0.00091 18.8 2.4 5.8 2 2 2 5 5 5 4 Leucine-rich repeat LRR_1 PF00560.33 OQS04834.1 - 4e-06 26.6 56.3 0.32 11.7 0.3 15.2 17 2 0 17 17 17 3 Leucine Rich Repeat LRR_5 PF13306.6 OQS04834.1 - 0.042 13.8 4.5 3.4 7.6 0.0 4.2 3 2 0 3 3 3 0 BspA type Leucine rich repeat region (6 copies) DUF3136 PF11334.8 OQS04834.1 - 0.076 12.8 0.0 0.36 10.7 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3136) LRR_6 PF13516.6 OQS04834.1 - 0.28 11.3 55.1 1.4 9.1 0.5 12.3 15 0 0 15 15 15 0 Leucine Rich repeat FNIP PF05725.12 OQS04834.1 - 0.82 9.9 10.2 0.16 12.2 1.8 4.1 4 0 0 4 4 4 0 FNIP Repeat Methyltransf_25 PF13649.6 OQS04835.1 - 1.1e-05 26.0 0.0 2.5e-05 24.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OQS04835.1 - 0.00014 21.7 0.1 0.00024 20.9 0.1 1.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 OQS04835.1 - 0.00095 19.0 0.0 0.0015 18.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OQS04835.1 - 0.024 15.3 0.0 0.053 14.2 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain DOT1 PF08123.13 OQS04835.1 - 0.043 13.4 0.1 0.086 12.4 0.0 1.5 1 1 1 2 2 2 0 Histone methylation protein DOT1 Methyltransf_4 PF02390.17 OQS04835.1 - 0.15 11.5 0.1 0.27 10.7 0.1 1.4 1 1 0 1 1 1 0 Putative methyltransferase SAPS PF04499.15 OQS04836.1 - 0.026 13.3 0.0 0.042 12.6 0.0 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Peptidase_S9_N PF02897.15 OQS04837.1 - 5.4e-79 265.9 2.8 7.3e-79 265.5 2.8 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase, N-terminal beta-propeller domain Peptidase_S9 PF00326.21 OQS04837.1 - 8.6e-63 211.6 0.0 1.5e-62 210.9 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family TMEM132D_C PF15706.5 OQS04838.1 - 0.013 15.3 0.0 0.026 14.3 0.0 1.5 1 0 0 1 1 1 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term Phage_holin_2_4 PF16082.5 OQS04838.1 - 0.048 13.4 0.2 0.14 11.9 0.2 1.9 1 0 0 1 1 1 0 Bacteriophage holin family, superfamily II-like Pam17 PF08566.10 OQS04838.1 - 0.19 11.6 0.7 0.48 10.3 0.7 1.6 1 0 0 1 1 1 0 Mitochondrial import protein Pam17 ECH_1 PF00378.20 OQS04839.1 - 4.3e-51 173.7 0.3 7.3e-51 172.9 0.3 1.3 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 OQS04839.1 - 1e-29 104.1 0.5 6.9e-26 91.5 0.3 2.0 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase DUF1657 PF07870.11 OQS04839.1 - 0.12 12.3 1.0 0.38 10.7 1.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1657) WD40 PF00400.32 OQS04840.1 - 1.4e-18 66.9 17.6 1.9e-05 25.3 0.1 7.8 8 0 0 8 8 6 4 WD domain, G-beta repeat Zn_ribbon_17 PF17120.5 OQS04840.1 - 4e-08 32.7 3.1 1.4e-07 31.0 3.1 1.9 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type Dicty_CAR PF05462.11 OQS04840.1 - 5.3e-07 29.1 12.6 9.9e-07 28.2 12.6 1.3 1 0 0 1 1 1 1 Slime mold cyclic AMP receptor ANAPC4_WD40 PF12894.7 OQS04840.1 - 1.1e-06 28.9 0.2 0.0017 18.6 0.1 3.4 1 1 1 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain Exo_endo_phos PF03372.23 OQS04840.1 - 3.4e-06 26.7 0.0 8.6e-06 25.4 0.0 1.7 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family zinc_ribbon_16 PF17034.5 OQS04840.1 - 0.00019 21.7 3.9 0.0011 19.2 3.9 2.4 1 0 0 1 1 1 1 Zinc-ribbon like family TPR_8 PF13181.6 OQS04840.1 - 0.016 15.4 0.0 0.047 13.9 0.0 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_1 PF00515.28 OQS04840.1 - 0.031 14.1 0.1 0.089 12.7 0.1 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat zf-rbx1 PF12678.7 OQS04840.1 - 0.069 13.5 7.8 0.28 11.5 7.8 2.1 1 0 0 1 1 1 0 RING-H2 zinc finger domain PG_binding_4 PF12229.8 OQS04840.1 - 0.13 12.6 0.2 2.4 8.5 0.0 3.0 4 0 0 4 4 4 0 Putative peptidoglycan binding domain DUF1761 PF08570.10 OQS04840.1 - 0.34 11.2 2.0 1.5 9.1 0.9 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1761) UPF0183 PF03676.14 OQS04841.1 - 2.7e-80 270.6 0.1 4e-80 270.0 0.1 1.2 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0183) SF-assemblin PF06705.11 OQS04842.1 - 1.3e-40 139.3 24.7 1.6e-40 139.0 24.7 1.1 1 0 0 1 1 1 1 SF-assemblin/beta giardin DUF713 PF05218.14 OQS04842.1 - 0.0006 19.6 3.1 0.0006 19.6 3.1 2.2 1 1 1 2 2 2 1 Protein of unknown function (DUF713) Prominin PF05478.11 OQS04842.1 - 0.0074 14.3 12.1 0.0016 16.5 8.7 1.5 1 1 1 2 2 2 1 Prominin UBA_2 PF08587.11 OQS04842.1 - 0.1 12.7 1.5 12 6.1 0.1 2.8 2 0 0 2 2 2 0 Ubiquitin associated domain (UBA) Baculo_PEP_C PF04513.12 OQS04842.1 - 0.2 11.7 8.0 1 9.4 0.1 3.3 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Dynein_C PF18199.1 OQS04842.1 - 0.47 9.6 3.2 0.22 10.7 0.6 1.7 1 1 1 2 2 2 0 Dynein heavy chain C-terminal domain ApoLp-III PF07464.11 OQS04842.1 - 0.64 10.1 10.7 1.2 9.2 4.4 3.3 1 1 2 3 3 3 0 Apolipophorin-III precursor (apoLp-III) TPR_19 PF14559.6 OQS04843.1 - 1.6e-08 34.9 7.6 0.00044 20.7 0.1 3.6 2 1 2 4 4 4 4 Tetratricopeptide repeat ImpA_N PF06812.12 OQS04843.1 - 0.0021 18.2 2.4 0.38 10.9 0.0 3.3 3 0 0 3 3 3 1 ImpA, N-terminal, type VI secretion system ANAPC3 PF12895.7 OQS04843.1 - 0.0038 17.4 4.2 0.0068 16.6 0.1 3.1 2 1 1 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 DUF627 PF04781.12 OQS04843.1 - 0.019 15.0 1.8 0.47 10.5 0.1 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF627) ChAPs PF09295.10 OQS04843.1 - 0.15 11.0 3.7 0.29 10.1 0.3 2.2 1 1 1 2 2 2 0 ChAPs (Chs5p-Arf1p-binding proteins) TPR_14 PF13428.6 OQS04843.1 - 0.15 12.9 1.5 14 6.8 0.0 4.3 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_2 PF07719.17 OQS04843.1 - 1.1 9.5 7.3 11 6.4 0.0 4.5 6 0 0 6 6 6 0 Tetratricopeptide repeat FUN14 PF04930.15 OQS04845.1 - 1.4e-19 70.3 0.1 2.4e-19 69.6 0.1 1.3 1 0 0 1 1 1 1 FUN14 family EF-hand_1 PF00036.32 OQS04845.1 - 2.2e-05 23.7 0.0 5.3e-05 22.5 0.0 1.7 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 OQS04845.1 - 0.026 14.4 0.0 0.067 13.2 0.0 1.6 1 0 0 1 1 1 0 EF-hand domain EF-hand_5 PF13202.6 OQS04845.1 - 0.042 13.3 0.0 0.088 12.3 0.0 1.5 1 0 0 1 1 1 0 EF hand EF-hand_7 PF13499.6 OQS04845.1 - 0.12 12.9 0.1 0.57 10.7 0.0 2.2 2 1 0 2 2 2 0 EF-hand domain pair Met_synt_B12 PF02965.17 OQS04846.1 - 1.1e-110 369.5 0.0 1.9e-110 368.6 0.0 1.4 1 0 0 1 1 1 1 Vitamin B12 dependent methionine synthase, activation domain S-methyl_trans PF02574.16 OQS04846.1 - 6.4e-75 252.4 0.0 2.4e-74 250.5 0.0 2.0 2 0 0 2 2 2 1 Homocysteine S-methyltransferase Pterin_bind PF00809.22 OQS04846.1 - 1.7e-53 181.8 0.4 3.9e-53 180.6 0.4 1.7 1 0 0 1 1 1 1 Pterin binding enzyme B12-binding_2 PF02607.17 OQS04846.1 - 1.8e-23 82.8 0.0 1.8e-23 82.8 0.0 3.1 4 0 0 4 4 4 1 B12 binding domain B12-binding PF02310.19 OQS04846.1 - 6.7e-17 61.7 0.3 4.7e-16 58.9 0.2 2.6 2 0 0 2 2 2 1 B12 binding domain IFT57 PF10498.9 OQS04847.1 - 3.9e-105 351.8 13.8 5.9e-105 351.2 13.8 1.3 1 0 0 1 1 1 1 Intra-flagellar transport protein 57 DeoC PF01791.9 OQS04847.1 - 3e-16 59.8 1.3 3e-16 59.8 1.3 1.8 2 0 0 2 2 2 1 DeoC/LacD family aldolase zf-BED PF02892.15 OQS04847.1 - 0.0014 18.6 1.4 0.002 18.1 0.1 1.9 2 0 0 2 2 2 1 BED zinc finger Sec34 PF04136.15 OQS04847.1 - 0.011 15.6 1.9 0.033 14.1 1.9 1.8 1 0 0 1 1 1 0 Sec34-like family DUF948 PF06103.11 OQS04847.1 - 0.028 14.7 1.7 0.12 12.7 1.7 2.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) DASH_Spc34 PF08657.10 OQS04847.1 - 0.048 13.4 5.9 0.12 12.2 5.9 1.7 1 0 0 1 1 1 0 DASH complex subunit Spc34 WASH_WAHD PF11945.8 OQS04847.1 - 0.06 12.9 3.1 0.044 13.3 0.7 1.9 2 0 0 2 2 2 0 WAHD domain of WASH complex DUF1664 PF07889.12 OQS04847.1 - 0.23 11.5 4.4 0.73 9.9 4.2 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) DASH_Duo1 PF08651.10 OQS04847.1 - 0.23 11.3 3.4 0.61 9.9 0.4 2.6 2 0 0 2 2 2 0 DASH complex subunit Duo1 Baculo_PEP_C PF04513.12 OQS04847.1 - 0.37 10.8 2.0 1.1 9.3 2.0 1.7 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Occludin_ELL PF07303.13 OQS04847.1 - 0.69 10.7 9.4 0.091 13.5 2.1 3.1 3 0 0 3 3 3 0 Occludin homology domain Spectrin PF00435.21 OQS04847.1 - 0.85 10.1 7.4 0.44 11.1 4.3 2.2 2 0 0 2 2 2 0 Spectrin repeat LPD5 PF18799.1 OQS04847.1 - 1 9.8 4.9 0.33 11.4 1.6 1.9 2 0 0 2 2 1 0 Large polyvalent protein-associated domain 5 KELK PF15796.5 OQS04847.1 - 1.3 9.5 6.3 1 9.9 2.8 2.8 2 1 0 2 2 1 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase TMPIT PF07851.13 OQS04847.1 - 1.6 7.9 7.3 0.76 9.0 4.6 1.8 2 0 0 2 2 2 0 TMPIT-like protein Pterin_4a PF01329.19 OQS04848.1 - 1.1e-30 105.6 0.1 1.3e-30 105.4 0.1 1.0 1 0 0 1 1 1 1 Pterin 4 alpha carbinolamine dehydratase Rhodanese PF00581.20 OQS04849.1 - 4.7e-10 39.9 0.0 1.2e-09 38.6 0.0 1.7 1 0 0 1 1 1 1 Rhodanese-like domain Cyto_heme_lyase PF01265.17 OQS04849.1 - 1.1 8.8 4.4 0.33 10.5 0.1 2.0 2 0 0 2 2 2 0 Cytochrome c/c1 heme lyase DDE_1 PF03184.19 OQS04850.1 - 9.8e-24 83.9 2.8 4.2e-13 49.3 0.1 2.9 2 1 1 3 3 3 2 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.16 OQS04850.1 - 0.16 12.0 0.3 0.16 12.0 0.3 1.9 2 0 0 2 2 2 0 Tc5 transposase DNA-binding domain VPS13_C PF16909.5 OQS04851.1 - 2.1e-19 70.0 0.6 6.5e-19 68.4 0.1 1.9 2 0 0 2 2 2 1 Vacuolar-sorting-associated 13 protein C-terminal IQ PF00612.27 OQS04851.1 - 0.11 12.3 0.9 0.32 10.9 0.9 1.8 1 0 0 1 1 1 0 IQ calmodulin-binding motif KxDL PF10241.9 OQS04852.1 - 0.0069 16.6 2.7 0.0069 16.6 2.7 3.2 3 1 0 3 3 3 1 Uncharacterized conserved protein DUF1664 PF07889.12 OQS04852.1 - 0.0071 16.4 3.3 0.0071 16.4 3.3 3.7 2 1 2 4 4 4 1 Protein of unknown function (DUF1664) Wtap PF17098.5 OQS04852.1 - 0.0092 15.9 2.1 0.0092 15.9 2.1 3.3 2 1 1 3 3 3 1 WTAP/Mum2p family Tup_N PF08581.10 OQS04852.1 - 0.044 14.1 18.4 0.68 10.3 2.3 3.1 1 1 1 3 3 3 0 Tup N-terminal MPS2 PF17060.5 OQS04852.1 - 0.059 12.6 14.7 0.19 10.9 6.7 2.1 1 1 1 2 2 2 0 Monopolar spindle protein 2 SlyX PF04102.12 OQS04852.1 - 0.88 10.2 24.5 0.091 13.4 3.4 4.2 3 1 1 4 4 4 0 SlyX KASH_CCD PF14662.6 OQS04852.1 - 1.2 8.9 30.1 2.5 7.9 22.6 2.9 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 or KASH TMF_TATA_bd PF12325.8 OQS04852.1 - 1.3 9.3 28.6 0.094 12.9 5.1 3.3 2 1 0 3 3 3 0 TATA element modulatory factor 1 TATA binding Baculo_PEP_C PF04513.12 OQS04852.1 - 3.1 7.8 5.4 6.1 6.9 2.6 2.6 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Atg14 PF10186.9 OQS04852.1 - 3.2 6.7 17.0 0.78 8.8 13.7 1.6 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Spc7 PF08317.11 OQS04852.1 - 3.9 6.3 25.9 0.086 11.7 17.3 2.2 1 1 0 2 2 2 0 Spc7 kinetochore protein GIT_CC PF16559.5 OQS04852.1 - 4.3 7.3 9.6 1.2 9.1 1.4 2.9 2 1 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor MbeD_MobD PF04899.12 OQS04852.1 - 4.9 7.3 11.2 0.11 12.6 0.9 3.2 4 0 0 4 4 4 0 MbeD/MobD like GvpL_GvpF PF06386.11 OQS04852.1 - 5.8 6.8 12.8 1.1 9.2 7.2 2.2 2 1 0 2 2 2 0 Gas vesicle synthesis protein GvpL/GvpF ATG16 PF08614.11 OQS04852.1 - 6 7.0 30.5 0.69 10.1 8.1 3.0 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) BLOC1_2 PF10046.9 OQS04852.1 - 8 6.8 19.5 1.3 9.3 7.5 3.9 3 1 1 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 TMPIT PF07851.13 OQS04852.1 - 8.8 5.5 13.6 25 4.0 11.0 2.3 1 1 0 1 1 1 0 TMPIT-like protein MutL_C PF08676.11 OQS04853.1 - 1.7e-28 99.2 0.2 4e-28 98.0 0.2 1.6 1 0 0 1 1 1 1 MutL C terminal dimerisation domain DNA_mis_repair PF01119.19 OQS04853.1 - 1.5e-23 82.7 0.0 9.2e-23 80.2 0.0 2.2 2 0 0 2 2 2 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.6 OQS04853.1 - 7.1e-12 45.3 0.7 4.1e-11 42.9 0.0 2.3 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 OQS04853.1 - 1.2e-08 35.4 0.0 4e-08 33.8 0.0 1.9 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Arf PF00025.21 OQS04854.1 - 4.1e-27 94.7 0.0 4.8e-27 94.5 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 OQS04854.1 - 4.8e-05 23.6 0.0 6.3e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Gtr1_RagA PF04670.12 OQS04854.1 - 0.00014 21.4 0.0 0.00017 21.0 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 OQS04854.1 - 0.00055 19.4 0.0 0.00064 19.2 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.22 OQS04854.1 - 0.22 11.1 0.0 0.23 11.0 0.0 1.2 1 0 0 1 1 1 0 Ras family SAPIS-gp6 PF16722.5 OQS04855.1 - 0.04 14.3 0.1 0.16 12.4 0.1 2.0 1 0 0 1 1 1 0 Pathogenicity island protein gp6 in Staphylococcus bZIP_1 PF00170.21 OQS04856.1 - 0.00023 21.2 1.2 0.00048 20.2 1.2 1.6 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 OQS04856.1 - 0.0049 16.9 2.9 0.0049 16.9 2.9 2.1 2 0 0 2 2 2 1 Basic region leucine zipper Troponin PF00992.20 OQS04856.1 - 0.0054 17.0 10.5 0.086 13.1 10.7 2.1 1 1 1 2 2 2 1 Troponin BTB PF00651.31 OQS04856.1 - 0.0075 16.5 0.5 0.012 15.8 0.5 1.2 1 0 0 1 1 1 1 BTB/POZ domain LPP PF04728.13 OQS04856.1 - 0.022 15.1 2.2 0.11 12.9 0.2 2.2 2 0 0 2 2 2 0 Lipoprotein leucine-zipper HAP1_N PF04849.13 OQS04856.1 - 0.12 11.6 12.3 0.12 11.6 0.9 2.1 1 1 1 2 2 2 0 HAP1 N-terminal conserved region DUF4407 PF14362.6 OQS04856.1 - 1.1 8.6 4.6 1.3 8.4 4.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Csm1_N PF18504.1 OQS04856.1 - 1.2 9.6 8.0 0.48 10.8 0.6 2.5 2 1 0 2 2 2 0 Csm1 N-terminal domain bZIP_1 PF00170.21 OQS04857.1 - 4.7e-05 23.4 5.5 7.4e-05 22.8 5.5 1.3 1 0 0 1 1 1 1 bZIP transcription factor DUF4337 PF14235.6 OQS04857.1 - 0.63 10.1 2.6 0.61 10.2 2.1 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4337) V-ATPase_G PF03179.15 OQS04858.1 - 1.4e-23 83.4 9.8 2e-23 82.9 9.8 1.2 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit DUF3552 PF12072.8 OQS04858.1 - 0.0094 15.4 10.0 0.011 15.1 10.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3552) CpeS PF09367.10 OQS04858.1 - 0.016 15.1 0.7 0.34 10.8 0.7 2.0 1 1 0 1 1 1 0 CpeS-like protein Epimerase PF01370.21 OQS04858.1 - 0.043 13.3 0.0 0.047 13.1 0.0 1.1 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family RNase_J_C PF17770.1 OQS04858.1 - 0.57 11.3 3.1 1.1 10.3 0.1 2.0 2 0 0 2 2 2 0 Ribonuclease J C-terminal domain ATP-synt_B PF00430.18 OQS04858.1 - 2.8 8.0 12.8 0.54 10.3 8.4 1.9 2 1 0 2 2 2 0 ATP synthase B/B' CF(0) Eapp_C PF10238.9 OQS04859.1 - 2.7 8.1 7.3 0.2 11.7 1.0 2.1 2 0 0 2 2 2 0 E2F-associated phosphoprotein Ank_2 PF12796.7 OQS04861.1 - 2.8e-13 50.3 0.0 2.2e-06 28.2 0.0 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OQS04861.1 - 0.00055 20.2 0.0 1.4 9.7 0.0 3.6 4 0 0 4 4 4 1 Ankyrin repeat Ank PF00023.30 OQS04861.1 - 0.004 17.5 0.0 4.5 7.9 0.0 3.3 3 0 0 3 3 3 1 Ankyrin repeat Ank_4 PF13637.6 OQS04861.1 - 0.039 14.6 0.1 4.6 7.9 0.0 2.6 2 1 0 2 2 2 0 Ankyrin repeats (many copies) SDF PF00375.18 OQS04863.1 - 1.5e-69 234.9 33.1 5.8e-69 233.0 33.1 1.7 1 1 0 1 1 1 1 Sodium:dicarboxylate symporter family DUF4501 PF14946.6 OQS04863.1 - 0.054 13.6 0.0 0.12 12.5 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4501) Pan3_PK PF18101.1 OQS04864.1 - 1.1e-54 184.2 0.3 1.7e-54 183.5 0.3 1.3 1 0 0 1 1 1 1 Pan3 Pseudokinase domain Pkinase PF00069.25 OQS04864.1 - 2.7e-09 36.8 0.0 4.9e-09 35.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQS04864.1 - 6.8e-06 25.5 0.0 1.1e-05 24.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase ETF PF01012.21 OQS04865.1 - 2.2e-44 151.5 1.4 2.8e-44 151.2 1.4 1.1 1 0 0 1 1 1 1 Electron transfer flavoprotein domain PP2C PF00481.21 OQS04866.1 - 4.9e-67 226.3 0.0 5.8e-67 226.0 0.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 OQS04866.1 - 2.4e-09 37.1 0.0 4.8e-09 36.2 0.0 1.5 1 0 0 1 1 1 1 Protein phosphatase 2C DUF5082 PF16888.5 OQS04867.1 - 0.69 10.2 5.3 9 6.6 1.5 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF5082) PX PF00787.24 OQS04869.1 - 0.00035 20.5 0.0 0.00047 20.1 0.0 1.1 1 0 0 1 1 1 1 PX domain PH PF00169.29 OQS04870.1 - 9.9e-08 32.4 0.1 1.7e-06 28.5 0.0 2.2 1 1 0 2 2 2 1 PH domain PH_8 PF15409.6 OQS04870.1 - 0.17 12.2 0.5 5.1 7.5 0.1 2.5 2 1 0 2 2 2 0 Pleckstrin homology domain zf-CCCH_4 PF18044.1 OQS04871.1 - 4.4e-10 39.1 6.2 9.7e-10 38.0 6.2 1.6 1 0 0 1 1 1 1 CCCH-type zinc finger Nucleoporin_FG PF13634.6 OQS04871.1 - 2.6e-08 34.6 139.3 0.0014 19.4 29.9 5.5 1 1 2 3 3 3 2 Nucleoporin FG repeat region zf_CCCH_4 PF18345.1 OQS04871.1 - 2e-06 27.7 7.9 4.1e-06 26.7 7.9 1.6 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH PF00642.24 OQS04871.1 - 5.8e-05 22.9 3.7 0.00012 21.9 3.7 1.5 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 OQS04871.1 - 0.00016 22.4 0.3 0.00033 21.3 0.3 1.5 1 0 0 1 1 1 1 Torus domain zf-CCCH_2 PF14608.6 OQS04871.1 - 1 10.0 11.2 0.18 12.3 7.3 1.9 2 0 0 2 2 2 0 RNA-binding, Nab2-type zinc finger Pkinase_Tyr PF07714.17 OQS04872.1 - 9.6e-31 107.0 0.0 1.3e-30 106.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OQS04872.1 - 4.9e-26 91.7 0.0 6.9e-26 91.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Ank_2 PF12796.7 OQS04872.1 - 2.1e-10 41.0 0.0 7.5e-10 39.3 0.0 1.9 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OQS04872.1 - 5e-09 35.7 0.0 4.3e-06 26.7 0.0 3.3 3 0 0 3 3 3 1 Ankyrin repeat Ank_4 PF13637.6 OQS04872.1 - 4.5e-08 33.5 0.0 1e-07 32.4 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.30 OQS04872.1 - 1.9e-07 31.2 0.2 3.3e-06 27.3 0.0 2.9 3 0 0 3 3 3 1 Ankyrin repeat Ank_5 PF13857.6 OQS04872.1 - 1.3e-05 25.4 0.0 6.4e-05 23.1 0.0 2.2 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Kinase-like PF14531.6 OQS04872.1 - 0.05 12.9 0.0 0.068 12.5 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Pkinase PF00069.25 OQS04873.1 - 8.8e-17 61.3 0.0 1.1e-16 61.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQS04873.1 - 1.8e-16 60.2 0.0 2.2e-16 60.0 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase DNA_pol3_delta2 PF13177.6 OQS04874.1 - 2.9e-12 46.7 0.0 3.9e-12 46.2 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA PF00004.29 OQS04874.1 - 2.4e-09 37.7 0.0 4.2e-09 36.9 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 OQS04874.1 - 0.0003 20.8 0.0 0.00045 20.2 0.0 1.4 1 1 0 1 1 1 1 Rad17 P-loop domain AAA_16 PF13191.6 OQS04874.1 - 0.0016 18.8 0.1 0.0041 17.5 0.1 1.7 1 1 0 1 1 1 1 AAA ATPase domain RuvB_N PF05496.12 OQS04874.1 - 0.0063 16.3 0.1 0.027 14.2 0.0 2.0 1 1 1 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_11 PF13086.6 OQS04874.1 - 0.0083 15.9 0.1 0.014 15.2 0.1 1.6 1 1 0 1 1 1 1 AAA domain Sigma54_activ_2 PF14532.6 OQS04874.1 - 0.01 15.9 0.1 0.69 10.0 0.1 2.4 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA_24 PF13479.6 OQS04874.1 - 0.022 14.5 0.0 0.033 13.9 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 OQS04874.1 - 0.024 14.9 0.0 0.048 13.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 OQS04874.1 - 0.035 13.5 0.1 0.3 10.4 0.1 2.1 1 1 0 1 1 1 0 Magnesium chelatase, subunit ChlI ABC_tran PF00005.27 OQS04874.1 - 0.062 13.8 0.0 0.089 13.3 0.0 1.2 1 0 0 1 1 1 0 ABC transporter AAA_5 PF07728.14 OQS04874.1 - 0.13 12.3 0.1 0.35 10.8 0.1 1.8 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_27 PF13514.6 OQS04874.1 - 0.19 11.3 0.0 0.28 10.7 0.0 1.2 1 0 0 1 1 1 0 AAA domain Pkinase_Tyr PF07714.17 OQS04875.1 - 5.6e-119 396.2 0.0 2.1e-34 119.0 0.0 4.2 4 0 0 4 4 4 4 Protein tyrosine kinase Pkinase PF00069.25 OQS04875.1 - 2e-114 381.4 0.0 3.1e-36 125.1 0.0 4.2 4 0 0 4 4 4 4 Protein kinase domain Myb_DNA-bind_6 PF13921.6 OQS04875.1 - 5.2e-18 65.1 2.1 1.3e-14 54.1 0.4 3.6 1 1 2 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 OQS04875.1 - 1.6e-16 60.2 2.1 4.5e-10 39.5 0.2 3.7 3 0 0 3 3 3 3 Myb-like DNA-binding domain Pkinase_fungal PF17667.1 OQS04875.1 - 2.1e-12 46.5 0.1 5.6e-07 28.7 0.1 2.7 3 0 0 3 3 3 2 Fungal protein kinase Ank_2 PF12796.7 OQS04875.1 - 5.6e-10 39.7 0.0 1.1e-09 38.7 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 OQS04875.1 - 3.9e-08 33.4 0.1 1.4e-05 25.3 0.0 3.1 2 0 0 2 2 2 1 Ankyrin repeat Kinase-like PF14531.6 OQS04875.1 - 4.4e-07 29.5 0.0 3.2 7.0 0.0 4.3 4 0 0 4 4 4 3 Kinase-like Ank_3 PF13606.6 OQS04875.1 - 1e-06 28.5 0.0 0.00029 21.0 0.0 2.9 2 0 0 2 2 2 1 Ankyrin repeat Ank_4 PF13637.6 OQS04875.1 - 1.7e-06 28.5 0.0 4.1e-06 27.2 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 OQS04875.1 - 3.7e-05 23.9 0.0 0.00013 22.2 0.0 2.0 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Kdo PF06293.14 OQS04875.1 - 0.00014 21.3 1.9 1.3 8.3 0.0 3.8 4 0 0 4 4 4 2 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OQS04875.1 - 0.00089 19.2 0.1 0.41 10.5 0.1 2.6 2 0 0 2 2 2 2 Phosphotransferase enzyme family Atg29_N PF18388.1 OQS04875.1 - 0.0067 16.2 0.1 0.017 14.9 0.1 1.7 1 0 0 1 1 1 1 Atg29 N-terminal domain Seadorna_VP7 PF07387.11 OQS04875.1 - 0.0078 15.3 0.7 3 6.8 0.0 2.8 3 0 0 3 3 3 2 Seadornavirus VP7 Haspin_kinase PF12330.8 OQS04875.1 - 0.011 14.7 0.0 1.7 7.5 0.0 2.8 3 0 0 3 3 3 0 Haspin like kinase domain Choline_kinase PF01633.20 OQS04876.1 - 0.049 13.2 1.4 3.7 7.1 0.0 2.8 2 1 1 3 3 3 0 Choline/ethanolamine kinase Proteasom_Rpn13 PF04683.13 OQS04878.1 - 3.2e-24 85.3 0.0 5.1e-24 84.6 0.0 1.4 1 0 0 1 1 1 1 Proteasome complex subunit Rpn13 ubiquitin receptor RPN13_C PF16550.5 OQS04878.1 - 4.3e-20 72.0 1.4 4.3e-20 72.0 1.4 2.5 2 1 1 3 3 3 1 UCH-binding domain RAP80_UIM PF18282.1 OQS04878.1 - 0.0091 15.7 2.1 0.026 14.3 2.1 1.7 1 0 0 1 1 1 1 RAP80 N-terminal ubiquitin interaction motif Ribosomal_60s PF00428.19 OQS04878.1 - 0.44 11.2 4.8 0.37 11.4 1.5 2.6 3 0 0 3 3 3 0 60s Acidic ribosomal protein Abhydrolase_6 PF12697.7 OQS04880.1 - 6.8e-16 59.5 0.0 8.9e-16 59.2 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 OQS04880.1 - 1.9e-10 40.9 0.2 1.5e-09 37.9 0.0 2.0 2 0 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 OQS04880.1 - 4.1e-08 32.8 0.0 4.9e-08 32.5 0.0 1.3 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Thioesterase PF00975.20 OQS04880.1 - 0.0049 17.0 0.0 0.009 16.2 0.0 1.4 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_3 PF07859.13 OQS04880.1 - 0.011 15.5 0.0 0.014 15.2 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold PGAP1 PF07819.13 OQS04880.1 - 0.047 13.4 0.1 0.15 11.7 0.1 1.8 1 1 1 2 2 2 0 PGAP1-like protein Glyco_trans_4_3 PF12000.8 OQS04880.1 - 0.095 12.4 0.0 0.19 11.4 0.0 1.5 1 0 0 1 1 1 0 Glycosyl transferase family 4 group Palm_thioest PF02089.15 OQS04880.1 - 0.11 12.3 0.0 0.18 11.6 0.0 1.3 1 0 0 1 1 1 0 Palmitoyl protein thioesterase Acyl_transf_1 PF00698.21 OQS04880.1 - 0.14 11.6 0.0 0.21 11.0 0.0 1.2 1 0 0 1 1 1 0 Acyl transferase domain Abhydro_lipase PF04083.16 OQS04880.1 - 0.16 11.6 0.1 1.3 8.6 0.0 2.2 2 0 0 2 2 2 0 Partial alpha/beta-hydrolase lipase region Beta-lactamase PF00144.24 OQS04886.1 - 1.3e-42 146.2 0.0 2e-42 145.6 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase DUF2251 PF10008.9 OQS04886.1 - 0.12 12.5 0.0 0.33 11.1 0.0 1.7 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2251) Pkinase_Tyr PF07714.17 OQS04887.1 - 9.1e-33 113.6 0.0 1.5e-32 112.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OQS04887.1 - 3.5e-32 111.8 0.2 6.1e-32 111.0 0.2 1.4 1 0 0 1 1 1 1 Protein kinase domain C2 PF00168.30 OQS04887.1 - 3e-15 56.3 0.0 1.3e-14 54.3 0.0 2.0 2 0 0 2 2 2 1 C2 domain Kdo PF06293.14 OQS04887.1 - 0.0077 15.6 0.6 0.016 14.6 0.6 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 OQS04887.1 - 0.024 13.9 0.0 0.042 13.2 0.0 1.3 1 0 0 1 1 1 0 Kinase-like CEP63 PF17045.5 OQS04887.1 - 0.042 13.8 3.6 0.083 12.8 3.6 1.4 1 0 0 1 1 1 0 Centrosomal protein of 63 kDa Atg14 PF10186.9 OQS04887.1 - 0.077 12.1 6.6 0.16 11.0 6.6 1.5 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 zf-RING_10 PF16685.5 OQS04887.1 - 0.1 12.8 0.7 0.2 11.8 0.7 1.4 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-ribbon_3 PF13248.6 OQS04887.1 - 0.16 11.4 0.4 0.33 10.4 0.4 1.6 1 0 0 1 1 1 0 zinc-ribbon domain TMF_TATA_bd PF12325.8 OQS04887.1 - 0.4 10.9 7.9 0.13 12.5 4.5 1.9 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding Syntaxin-6_N PF09177.11 OQS04887.1 - 1 10.0 3.6 3 8.5 3.6 1.9 1 1 0 1 1 1 0 Syntaxin 6, N-terminal zf-RanBP PF00641.18 OQS04887.1 - 1.2 8.5 5.6 2.2 7.7 5.6 1.4 1 0 0 1 1 1 0 Zn-finger in Ran binding protein and others CENP-F_leu_zip PF10473.9 OQS04887.1 - 1.2 9.1 6.9 0.27 11.3 3.3 1.8 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ZapB PF06005.12 OQS04887.1 - 2.4 8.7 12.2 0.24 11.9 4.8 3.1 4 0 0 4 4 4 0 Cell division protein ZapB Blo-t-5 PF11642.8 OQS04888.1 - 2.1 8.3 5.4 1.3 9.0 0.6 2.8 3 0 0 3 3 3 0 Mite allergen Blo t 5 Ion_trans PF00520.31 OQS04889.1 - 4.4e-20 71.9 22.3 6.8e-20 71.3 22.3 1.3 1 0 0 1 1 1 1 Ion transport protein cNMP_binding PF00027.29 OQS04889.1 - 2.2e-12 46.9 0.1 9.4e-12 44.9 0.1 2.1 2 0 0 2 2 2 1 Cyclic nucleotide-binding domain Ion_trans_2 PF07885.16 OQS04889.1 - 2.7e-10 40.1 8.7 6.5e-10 38.8 8.7 1.7 1 0 0 1 1 1 1 Ion channel Rad51 PF08423.11 OQS04890.1 - 7.6e-100 333.4 0.0 9.4e-100 333.1 0.0 1.1 1 0 0 1 1 1 1 Rad51 RecA PF00154.21 OQS04890.1 - 2e-06 27.5 0.1 3.2e-06 26.8 0.1 1.3 1 0 0 1 1 1 1 recA bacterial DNA recombination protein ATPase PF06745.13 OQS04890.1 - 5.3e-05 22.7 0.3 0.00025 20.5 0.3 2.1 1 1 0 1 1 1 1 KaiC AAA_25 PF13481.6 OQS04890.1 - 5.4e-05 22.9 0.0 8.5e-05 22.2 0.0 1.2 1 0 0 1 1 1 1 AAA domain HHH_5 PF14520.6 OQS04890.1 - 0.00012 22.6 0.5 0.00024 21.6 0.5 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix domain AAA_24 PF13479.6 OQS04890.1 - 0.0011 18.8 0.0 0.0019 17.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain HHH PF00633.23 OQS04890.1 - 0.11 12.4 0.0 0.24 11.3 0.0 1.6 1 0 0 1 1 1 0 Helix-hairpin-helix motif Ion_trans PF00520.31 OQS04892.1 - 1.9e-26 92.8 17.4 2.9e-26 92.2 17.4 1.2 1 0 0 1 1 1 1 Ion transport protein cNMP_binding PF00027.29 OQS04892.1 - 2.1e-13 50.1 0.1 9e-13 48.1 0.1 2.2 3 0 0 3 3 3 1 Cyclic nucleotide-binding domain Ion_trans_2 PF07885.16 OQS04892.1 - 2.5e-12 46.6 7.3 5.9e-12 45.4 7.3 1.7 1 0 0 1 1 1 1 Ion channel YabA PF06156.13 OQS04892.1 - 0.48 11.1 3.8 3.8 8.2 2.4 2.6 2 0 0 2 2 2 0 Initiation control protein YabA IRK PF01007.20 OQS04892.1 - 0.54 10.1 8.1 0.041 13.7 2.8 1.8 2 0 0 2 2 2 0 Inward rectifier potassium channel transmembrane domain UDPGP PF01704.18 OQS04893.1 - 1e-124 416.3 0.0 1.3e-124 416.0 0.0 1.1 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase PGM_PMM_I PF02878.16 OQS04893.1 - 3.3e-31 107.8 0.1 5.9e-31 107.0 0.1 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.16 OQS04893.1 - 4.1e-25 88.2 0.0 9.9e-25 87.0 0.0 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.16 OQS04893.1 - 5e-09 36.7 0.0 1.5e-08 35.2 0.0 1.9 1 1 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.20 OQS04893.1 - 2.3e-05 24.5 0.0 8.4e-05 22.7 0.0 2.0 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain Baculo_p26 PF04766.12 OQS04893.1 - 0.091 12.2 0.0 0.19 11.2 0.0 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus p26 protein Fer2 PF00111.27 OQS04894.1 - 7.2e-12 45.1 1.5 9.3e-12 44.7 1.5 1.2 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Rad51 PF08423.11 OQS04895.1 - 6e-23 81.4 0.1 6.8e-23 81.2 0.1 1.0 1 0 0 1 1 1 1 Rad51 DUF3145 PF11343.8 OQS04895.1 - 0.094 12.3 0.1 0.18 11.3 0.1 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3145) AAA_25 PF13481.6 OQS04895.1 - 0.1 12.2 0.0 0.13 11.8 0.0 1.2 1 0 0 1 1 1 0 AAA domain Porphobil_deam PF01379.20 OQS04896.1 - 2.5e-09 36.9 0.0 2.9e-09 36.7 0.0 1.1 1 0 0 1 1 1 1 Porphobilinogen deaminase, dipyromethane cofactor binding domain CUE PF02845.16 OQS04897.1 - 5.8e-07 29.1 0.0 1.9e-06 27.4 0.0 1.9 2 0 0 2 2 2 1 CUE domain TPPII PF12580.8 OQS04898.1 - 0.073 12.5 0.0 0.14 11.6 0.0 1.5 1 0 0 1 1 1 0 Tripeptidyl peptidase II DUF2779 PF11074.8 OQS04898.1 - 0.077 13.5 0.6 0.86 10.1 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function(DUF2779) AAT PF03417.16 OQS04899.1 - 4.3e-22 78.9 0.1 6.1e-22 78.4 0.1 1.2 1 0 0 1 1 1 1 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase Trehalose_PPase PF02358.16 OQS04900.1 - 4.4e-46 156.9 0.0 5.9e-46 156.5 0.0 1.2 1 0 0 1 1 1 1 Trehalose-phosphatase Hydrolase_3 PF08282.12 OQS04900.1 - 0.00094 19.0 0.0 0.0017 18.2 0.0 1.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase PfkB PF00294.24 OQS04900.1 - 0.0018 17.7 0.0 0.0027 17.1 0.0 1.2 1 0 0 1 1 1 1 pfkB family carbohydrate kinase HisKA_3 PF07730.13 OQS04900.1 - 0.098 13.2 0.1 0.39 11.3 0.0 2.0 2 0 0 2 2 2 0 Histidine kinase Peptidase_S8 PF00082.22 OQS04901.1 - 3.3e-80 269.5 3.3 7.8e-80 268.3 2.2 2.0 2 0 0 2 2 2 1 Subtilase family TPPII PF12580.8 OQS04901.1 - 4.6e-58 195.9 0.0 1e-57 194.7 0.0 1.6 1 0 0 1 1 1 1 Tripeptidyl peptidase II Porphobil_deam PF01379.20 OQS04902.1 - 1.6e-68 230.3 0.0 2.2e-68 229.8 0.0 1.2 1 0 0 1 1 1 1 Porphobilinogen deaminase, dipyromethane cofactor binding domain Porphobil_deamC PF03900.15 OQS04902.1 - 2.6e-15 56.6 0.2 5.2e-15 55.6 0.2 1.5 1 0 0 1 1 1 1 Porphobilinogen deaminase, C-terminal domain LepA_C PF06421.12 OQS04902.1 - 0.09 12.9 0.0 0.5 10.5 0.0 2.1 2 0 0 2 2 2 0 GTP-binding protein LepA C-terminus Ank_4 PF13637.6 OQS04903.1 - 4.7e-43 145.0 0.7 1.2e-11 44.8 0.0 4.4 1 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 OQS04903.1 - 7.1e-43 143.2 1.9 1.9e-07 31.2 0.0 6.2 6 0 0 6 6 6 6 Ankyrin repeat Ank_2 PF12796.7 OQS04903.1 - 5.7e-42 142.2 0.8 2.1e-18 66.7 0.0 3.0 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OQS04903.1 - 3.1e-30 100.8 0.2 4.1e-05 23.6 0.0 6.1 6 0 0 6 6 6 5 Ankyrin repeat Ank_5 PF13857.6 OQS04903.1 - 6.8e-24 83.6 0.1 6e-11 42.4 0.0 3.4 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Arg_repressor PF01316.21 OQS04903.1 - 0.00018 21.2 0.8 0.018 14.8 0.0 3.7 5 0 0 5 5 5 1 Arginine repressor, DNA binding domain PH PF00169.29 OQS04904.1 - 3.3e-69 230.1 1.2 4.9e-17 62.3 0.1 5.4 5 0 0 5 5 5 5 PH domain PH_11 PF15413.6 OQS04904.1 - 5.8e-25 87.8 9.5 0.00026 21.3 0.1 6.4 5 2 0 5 5 5 5 Pleckstrin homology domain PH_3 PF14593.6 OQS04904.1 - 2.7e-18 66.0 2.2 0.0023 18.0 0.0 7.9 5 5 0 5 5 5 3 PH domain PH_8 PF15409.6 OQS04904.1 - 5.7e-15 55.4 15.7 0.0045 17.2 0.6 7.9 5 4 0 5 5 5 5 Pleckstrin homology domain Mcp5_PH PF12814.7 OQS04904.1 - 7.6e-15 55.1 0.4 0.0099 16.0 0.0 5.3 5 0 0 5 5 5 4 Meiotic cell cortex C-terminal pleckstrin homology PH_9 PF15410.6 OQS04904.1 - 1.5e-08 35.0 10.5 0.9 9.9 0.0 7.5 5 4 0 5 5 5 3 Pleckstrin homology domain PH_2 PF08458.10 OQS04904.1 - 2.2e-05 24.7 0.1 1.1 9.6 0.0 4.1 4 0 0 4 4 4 1 Plant pleckstrin homology-like region PH_12 PF16457.5 OQS04904.1 - 0.07 13.7 6.4 16 6.0 0.2 4.8 5 1 0 5 5 5 0 Pleckstrin homology domain HGTP_anticodon PF03129.20 OQS04905.1 - 3.7e-19 68.7 0.0 9.5e-19 67.4 0.0 1.8 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2b PF00587.25 OQS04905.1 - 3.6e-11 43.4 0.0 1.8e-10 41.1 0.0 2.1 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) WHEP-TRS PF00458.20 OQS04905.1 - 6.7e-09 35.8 1.8 1.5e-08 34.7 1.8 1.5 1 0 0 1 1 1 1 WHEP-TRS domain Pkinase_Tyr PF07714.17 OQS04906.1 - 6.5e-40 137.0 0.0 9.8e-40 136.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OQS04906.1 - 7.2e-38 130.5 0.0 1.1e-37 129.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 OQS04906.1 - 0.0013 17.5 0.0 0.0022 16.8 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase DZR PF12773.7 OQS04906.1 - 0.0022 18.0 7.6 0.0055 16.7 7.6 1.8 1 0 0 1 1 1 1 Double zinc ribbon zinc_ribbon_2 PF13240.6 OQS04906.1 - 0.71 9.7 11.2 0.14 11.9 2.6 3.1 3 0 0 3 3 3 0 zinc-ribbon domain Ank_4 PF13637.6 OQS04907.1 - 2.3e-15 56.7 0.2 4.2e-07 30.4 0.1 2.1 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 OQS04907.1 - 2.3e-15 56.9 0.3 2.7e-15 56.7 0.3 1.1 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 OQS04907.1 - 9.8e-14 51.1 0.9 3.8e-05 23.9 0.1 3.1 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.6 OQS04907.1 - 2.6e-13 49.9 2.8 6.6e-07 29.5 0.6 2.1 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQS04907.1 - 5.7e-13 47.8 0.4 0.00037 20.7 0.1 3.1 3 0 0 3 3 3 2 Ankyrin repeat LMSTEN PF07988.12 OQS04907.1 - 0.092 12.2 0.3 0.43 10.1 0.1 1.9 2 0 0 2 2 2 0 LMSTEN motif TPR_1 PF00515.28 OQS04908.1 - 3.8e-24 83.4 4.9 2e-08 33.7 0.0 3.9 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.17 OQS04908.1 - 1.8e-20 71.3 2.8 7.2e-08 32.0 0.0 3.8 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 OQS04908.1 - 2.7e-16 59.0 0.7 4.5e-07 29.4 0.3 3.5 2 1 1 3 3 3 2 TPR repeat TPR_8 PF13181.6 OQS04908.1 - 8.6e-13 47.4 0.8 0.0016 18.5 0.0 3.8 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.6 OQS04908.1 - 1e-09 38.9 1.0 0.00067 20.3 0.7 2.7 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.6 OQS04908.1 - 2.3e-09 37.0 0.8 6.1e-05 23.1 0.5 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 OQS04908.1 - 8.9e-09 34.8 0.7 0.018 15.0 0.0 3.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.6 OQS04908.1 - 5.5e-08 32.8 1.1 0.0058 16.7 0.0 2.8 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 OQS04908.1 - 1.2e-07 31.9 1.4 0.079 13.3 0.0 3.4 1 1 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 OQS04908.1 - 1.3e-06 28.7 0.6 0.024 15.4 0.0 3.7 1 1 2 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 OQS04908.1 - 2.3e-06 28.0 0.6 0.058 13.9 0.7 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 OQS04908.1 - 2.2e-05 24.5 0.4 0.11 12.6 0.0 3.5 3 0 0 3 3 3 1 Fis1 C-terminal tetratricopeptide repeat ANAPC3 PF12895.7 OQS04908.1 - 0.049 13.9 2.1 0.18 12.0 2.2 1.9 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.6 OQS04908.1 - 0.2 11.6 6.0 6.8 6.7 0.2 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat LolB PF03550.14 OQS04908.1 - 0.56 10.2 5.5 1.3 9.0 5.5 1.7 1 1 0 1 1 1 0 Outer membrane lipoprotein LolB PH PF00169.29 OQS04909.1 - 0.00042 20.8 0.0 0.00086 19.8 0.0 1.6 1 0 0 1 1 1 1 PH domain DUF5098 PF17023.5 OQS04909.1 - 0.016 14.2 0.9 0.17 10.8 0.0 2.7 3 1 0 3 3 3 0 Domain of unknown function (DUF5098) TA0956 PF11513.8 OQS04909.1 - 0.16 12.2 0.0 0.35 11.1 0.0 1.5 1 0 0 1 1 1 0 Thermoplasma acidophilum protein TA0956 Dynein_light PF01221.18 OQS04910.1 - 4.8e-17 62.1 0.7 8.6e-17 61.2 0.7 1.3 1 0 0 1 1 1 1 Dynein light chain type 1 EXOSC1 PF10447.9 OQS04910.1 - 5.9e-13 49.4 0.6 1.4e-08 35.3 0.0 2.5 1 1 1 2 2 2 2 Exosome component EXOSC1/CSL4 ECR1_N PF14382.6 OQS04910.1 - 2.5e-10 40.0 2.0 4e-10 39.3 1.2 1.8 2 0 0 2 2 2 1 Exosome complex exonuclease RRP4 N-terminal region DUF2190 PF09956.9 OQS04910.1 - 0.062 13.8 0.1 0.11 13.0 0.1 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2190) ANAPC10 PF03256.16 OQS04911.1 - 4.9e-66 221.9 0.1 5.3e-66 221.8 0.1 1.0 1 0 0 1 1 1 1 Anaphase-promoting complex, subunit 10 (APC10) F5_F8_type_C PF00754.25 OQS04911.1 - 0.0011 19.1 0.0 0.0016 18.6 0.0 1.3 1 0 0 1 1 1 1 F5/8 type C domain PITH PF06201.13 OQS04911.1 - 0.089 13.0 0.1 0.24 11.6 0.1 1.7 1 1 1 2 2 2 0 PITH domain Helicase_C_2 PF13307.6 OQS04912.1 - 2.7e-54 183.9 0.1 8.9e-54 182.2 0.0 2.0 2 0 0 2 2 1 1 Helicase C-terminal domain DEAD_2 PF06733.15 OQS04912.1 - 2.4e-46 157.5 0.0 2.4e-46 157.5 0.0 1.9 2 0 0 2 2 1 1 DEAD_2 zf-C3HC4_3 PF13920.6 OQS04912.1 - 1.7e-07 31.0 8.9 1.7e-07 31.0 8.9 1.9 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 OQS04912.1 - 2.4e-06 27.3 11.7 7.1e-06 25.8 11.7 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) DEAD PF00270.29 OQS04912.1 - 2.7e-06 27.3 0.3 0.00024 20.9 0.0 3.3 3 0 0 3 3 3 1 DEAD/DEAH box helicase zf-C3HC4 PF00097.25 OQS04912.1 - 1.2e-05 25.1 11.1 3.4e-05 23.6 11.1 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 OQS04912.1 - 1.9e-05 24.4 10.1 5.4e-05 23.0 10.1 1.8 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 ResIII PF04851.15 OQS04912.1 - 2.7e-05 24.3 0.1 0.00082 19.4 0.1 2.9 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit zf-RING_5 PF14634.6 OQS04912.1 - 3.8e-05 23.6 9.7 9.4e-05 22.3 9.7 1.7 1 0 0 1 1 1 1 zinc-RING finger domain PhoH PF02562.16 OQS04912.1 - 0.0019 17.7 0.0 1.5 8.2 0.0 2.5 2 0 0 2 2 2 2 PhoH-like protein zf-RING_UBOX PF13445.6 OQS04912.1 - 0.0024 17.9 7.6 0.0048 16.9 6.1 2.4 1 1 1 2 2 2 1 RING-type zinc-finger zf-RING_2 PF13639.6 OQS04912.1 - 0.0026 18.1 11.5 0.0026 18.1 11.5 2.4 2 0 0 2 2 1 1 Ring finger domain CoA_transf_3 PF02515.17 OQS04912.1 - 0.0045 16.1 0.0 0.0074 15.5 0.0 1.3 1 0 0 1 1 1 1 CoA-transferase family III zf-RING_4 PF14570.6 OQS04912.1 - 0.02 14.7 8.4 0.073 12.9 8.4 2.0 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain AAA_11 PF13086.6 OQS04912.1 - 0.033 14.0 0.1 0.093 12.5 0.0 1.9 2 0 0 2 2 2 0 AAA domain HBB PF06777.11 OQS04912.1 - 0.034 13.8 0.0 0.073 12.7 0.0 1.5 1 0 0 1 1 1 0 Helical and beta-bridge domain DUF3489 PF11994.8 OQS04912.1 - 0.041 13.9 0.0 0.11 12.6 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3489) zf-UDP PF14569.6 OQS04912.1 - 0.048 13.8 3.7 0.19 11.9 3.7 2.1 1 1 0 1 1 1 0 Zinc-binding RING-finger T2SSE PF00437.20 OQS04912.1 - 0.14 11.1 0.0 0.31 10.1 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein zf-C3HC4_4 PF15227.6 OQS04912.1 - 0.3 11.3 14.2 0.38 11.0 12.3 2.3 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-RING_6 PF14835.6 OQS04912.1 - 2.1 8.3 6.2 4.8 7.1 5.4 2.0 2 0 0 2 2 2 0 zf-RING of BARD1-type protein GrpE PF01025.19 OQS04913.1 - 1.2e-48 164.9 0.2 1.5e-48 164.6 0.2 1.1 1 0 0 1 1 1 1 GrpE ZapB PF06005.12 OQS04913.1 - 0.0047 17.3 0.3 0.0081 16.6 0.3 1.4 1 0 0 1 1 1 1 Cell division protein ZapB DivIC PF04977.15 OQS04913.1 - 0.05 13.4 1.9 0.1 12.4 1.1 2.0 2 0 0 2 2 2 0 Septum formation initiator EF-hand_7 PF13499.6 OQS04913.1 - 0.082 13.4 0.1 0.3 11.6 0.1 2.1 1 1 0 1 1 1 0 EF-hand domain pair ATG16 PF08614.11 OQS04913.1 - 0.095 12.9 5.0 0.16 12.2 5.0 1.5 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) RtcB PF01139.17 OQS04915.1 - 1.4e-53 182.6 0.0 1.6e-53 182.4 0.0 1.0 1 0 0 1 1 1 1 tRNA-splicing ligase RtcB Ricin_B_lectin PF00652.22 OQS04916.1 - 2.9e-28 98.7 23.6 4.5e-12 46.3 2.6 2.6 1 1 2 3 3 3 3 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.6 OQS04916.1 - 2.1e-10 41.2 10.4 3.4e-05 24.5 1.4 3.9 1 1 3 4 4 4 4 Ricin-type beta-trefoil lectin domain-like Herpes_BLLF1 PF05109.13 OQS04916.1 - 0.0082 14.2 30.9 0.009 14.1 30.9 1.1 1 0 0 1 1 1 1 Herpes virus major outer envelope glycoprotein (BLLF1) Cadherin PF00028.17 OQS04916.1 - 0.092 13.2 0.0 27 5.3 0.0 2.6 2 0 0 2 2 2 0 Cadherin domain Methyltransf_33 PF10017.9 OQS04917.1 - 2.2e-91 306.2 1.1 2.6e-91 306.0 1.1 1.0 1 0 0 1 1 1 1 Histidine-specific methyltransferase, SAM-dependent 2-Hacid_dh_C PF02826.19 OQS04917.1 - 0.014 14.8 0.0 0.046 13.1 0.0 1.8 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Pkinase PF00069.25 OQS04919.1 - 6.4e-17 61.8 5.3 7.4e-17 61.6 5.3 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQS04919.1 - 2.8e-06 26.8 5.1 3.2e-06 26.6 5.1 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 OQS04919.1 - 0.0036 16.7 0.9 0.004 16.5 0.9 1.1 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 OQS04919.1 - 0.0076 15.1 0.2 0.0096 14.7 0.2 1.1 1 0 0 1 1 1 1 Fungal protein kinase YrbL-PhoP_reg PF10707.9 OQS04919.1 - 0.012 15.1 0.7 0.02 14.4 0.4 1.4 1 1 0 1 1 1 0 PhoP regulatory network protein YrbL FTA2 PF13095.6 OQS04919.1 - 0.016 14.8 0.1 0.016 14.8 0.1 1.2 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 CNOT11 PF10155.9 OQS04919.1 - 0.065 13.4 1.2 0.082 13.1 0.5 1.4 1 1 1 2 2 2 0 CCR4-NOT transcription complex subunit 11 APH PF01636.23 OQS04919.1 - 0.12 12.2 0.0 0.15 12.0 0.0 1.1 1 0 0 1 1 1 0 Phosphotransferase enzyme family CBM_1 PF00734.18 OQS04921.1 - 1.9e-11 43.7 34.0 2.1e-10 40.4 4.7 4.7 4 2 0 4 4 4 3 Fungal cellulose binding domain HOCHOB PF17943.1 OQS04921.1 - 2 9.1 7.7 20 5.9 0.3 3.1 3 0 0 3 3 3 0 Homeobox-cysteine loop-homeobox CBM_1 PF00734.18 OQS04922.1 - 3.5e-27 94.0 159.2 3e-09 36.7 6.6 15.4 14 2 2 16 16 16 10 Fungal cellulose binding domain zf-RING_2 PF13639.6 OQS04923.1 - 3.1e-13 49.8 7.5 3.1e-13 49.8 7.5 2.3 3 0 0 3 3 2 1 Ring finger domain zf-rbx1 PF12678.7 OQS04923.1 - 3.1e-10 40.2 5.6 3.1e-10 40.2 5.6 2.2 3 0 0 3 3 2 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 OQS04923.1 - 4.4e-07 29.8 1.3 4.4e-07 29.8 1.3 2.4 2 1 0 2 2 2 1 RING-type zinc-finger Prok-RING_4 PF14447.6 OQS04923.1 - 5.2e-07 29.4 6.2 5.3e-06 26.2 5.9 2.5 2 1 1 3 3 3 1 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 OQS04923.1 - 8.9e-07 28.9 9.6 3.1e-05 24.0 6.7 2.9 2 1 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4 PF00097.25 OQS04923.1 - 1.2e-06 28.2 7.8 3.2e-06 26.9 6.9 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 OQS04923.1 - 1.6e-06 27.8 3.4 1.6e-06 27.8 3.4 2.3 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 OQS04923.1 - 1e-05 25.3 10.2 1e-05 25.3 10.2 2.8 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) PX PF00787.24 OQS04923.1 - 1.5e-05 24.9 0.1 2.7e-05 24.1 0.1 1.4 1 0 0 1 1 1 1 PX domain zf-RING_5 PF14634.6 OQS04923.1 - 2.4e-05 24.2 6.7 2.4e-05 24.2 6.7 2.1 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 OQS04923.1 - 2.5e-05 24.1 7.4 2.5e-05 24.1 7.4 2.5 2 1 1 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zinc_ribbon_16 PF17034.5 OQS04923.1 - 0.0044 17.2 1.3 0.011 16.0 1.3 1.7 1 0 0 1 1 1 1 Zinc-ribbon like family zf-Nse PF11789.8 OQS04923.1 - 0.043 13.6 4.2 6.7 6.6 0.0 2.5 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit Zn_ribbon_17 PF17120.5 OQS04923.1 - 0.049 13.3 9.6 0.2 11.3 9.6 2.1 1 1 0 1 1 1 0 Zinc-ribbon, C4HC2 type U-box PF04564.15 OQS04923.1 - 0.058 13.6 0.0 0.18 12.0 0.0 1.8 1 0 0 1 1 1 0 U-box domain FANCL_C PF11793.8 OQS04923.1 - 0.43 10.8 11.1 0.2 11.9 6.5 2.8 3 1 0 3 3 3 0 FANCL C-terminal domain zf-C3HC4_4 PF15227.6 OQS04923.1 - 2.8 8.2 10.3 9.9 6.4 8.9 2.7 2 1 0 2 2 1 0 zinc finger of C3HC4-type, RING zf-C3H2C3 PF17122.5 OQS04923.1 - 2.8 8.0 9.1 1.8 8.6 6.1 2.3 2 0 0 2 2 2 0 Zinc-finger Prok-RING_1 PF14446.6 OQS04923.1 - 2.8 7.9 10.5 0.47 10.4 2.8 2.8 3 0 0 3 3 3 0 Prokaryotic RING finger family 1 RINGv PF12906.7 OQS04923.1 - 4.3 7.6 9.4 26 5.0 9.1 2.4 1 1 1 2 2 2 0 RING-variant domain Vps62 PF06101.11 OQS04924.1 - 0.029 12.7 0.3 4.1 5.6 0.1 3.0 2 1 0 3 3 3 0 Vacuolar protein sorting-associated protein 62 RIX1 PF08167.12 OQS04924.1 - 0.086 12.6 0.2 0.38 10.5 0.1 2.2 2 1 0 2 2 2 0 rRNA processing/ribosome biogenesis Syntaxin_2 PF14523.6 OQS04924.1 - 1.2 9.5 4.4 9.7 6.6 0.0 3.2 2 1 1 3 3 3 0 Syntaxin-like protein His_Phos_2 PF00328.22 OQS04925.1 - 0.0028 17.1 0.0 0.0034 16.8 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Vps62 PF06101.11 OQS04926.1 - 0.00027 19.4 4.6 1.6 6.9 0.1 4.4 3 2 1 5 5 5 3 Vacuolar protein sorting-associated protein 62 T6PP_N PF18572.1 OQS04926.1 - 0.0073 16.1 0.0 0.34 10.7 0.0 2.6 2 0 0 2 2 2 1 Trehalose-6-phosphate phosphatase N-terminal helical bundle domain Serine_rich PF08824.10 OQS04926.1 - 0.1 12.6 0.6 0.31 11.0 0.6 1.8 1 0 0 1 1 1 0 Serine rich protein interaction domain LicD PF04991.13 OQS04927.1 - 0.11 12.6 0.1 0.23 11.5 0.1 1.5 1 0 0 1 1 1 0 LicD family SDF PF00375.18 OQS04928.1 - 6.2e-96 321.8 32.0 7.1e-96 321.6 32.0 1.0 1 0 0 1 1 1 1 Sodium:dicarboxylate symporter family SPC12 PF06645.13 OQS04928.1 - 8.2 6.6 8.5 0.64 10.2 0.5 3.2 3 0 0 3 3 3 0 Microsomal signal peptidase 12 kDa subunit (SPC12) FYVE PF01363.21 OQS04929.1 - 3e-21 75.3 50.4 1.5e-09 37.8 13.9 3.4 3 0 0 3 3 3 3 FYVE zinc finger FYVE PF01363.21 OQS04930.1 - 6.6e-45 151.1 62.8 1.7e-14 53.7 8.5 4.4 4 0 0 4 4 4 4 FYVE zinc finger GAF PF01590.26 OQS04930.1 - 3.4e-13 50.4 0.0 1.2e-05 26.0 0.0 2.8 2 0 0 2 2 2 2 GAF domain Pkinase PF00069.25 OQS04931.1 - 1.7e-19 70.2 0.0 3.5e-19 69.2 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain SET PF00856.28 OQS04931.1 - 9.2e-16 58.7 1.6 3.3e-15 56.9 0.3 2.6 2 1 0 2 2 2 1 SET domain AWS PF17907.1 OQS04931.1 - 9.4e-12 44.8 3.9 2.3e-11 43.5 3.9 1.7 1 0 0 1 1 1 1 AWS domain TPR_12 PF13424.6 OQS04931.1 - 1.2e-09 38.3 20.4 0.00062 20.0 0.3 6.0 6 0 0 6 6 6 2 Tetratricopeptide repeat Cyclin_N PF00134.23 OQS04931.1 - 1.1e-07 31.6 0.4 3.2e-07 30.1 0.4 1.8 1 0 0 1 1 1 1 Cyclin, N-terminal domain TPR_8 PF13181.6 OQS04931.1 - 0.00031 20.7 0.1 0.00031 20.7 0.1 5.1 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_2 PF07719.17 OQS04931.1 - 0.00058 19.8 30.3 0.0041 17.1 0.3 8.3 9 0 0 9 9 9 2 Tetratricopeptide repeat TPR_7 PF13176.6 OQS04931.1 - 0.0014 18.5 8.0 0.0047 16.9 0.2 4.7 4 0 0 4 4 4 1 Tetratricopeptide repeat Pkinase_Tyr PF07714.17 OQS04931.1 - 0.0015 17.9 0.0 0.0041 16.4 0.0 1.8 1 0 0 1 1 1 1 Protein tyrosine kinase TPR_10 PF13374.6 OQS04931.1 - 0.0029 17.4 0.3 0.0029 17.4 0.3 4.7 5 0 0 5 5 5 1 Tetratricopeptide repeat Kinase-like PF14531.6 OQS04931.1 - 0.017 14.4 0.0 0.072 12.4 0.0 2.0 1 1 0 1 1 1 0 Kinase-like TPR_1 PF00515.28 OQS04931.1 - 0.02 14.7 28.1 0.025 14.4 0.2 7.5 9 0 0 9 9 9 0 Tetratricopeptide repeat FYVE PF01363.21 OQS04932.1 - 2.1e-16 59.8 53.3 2.2e-10 40.5 14.0 3.3 3 0 0 3 3 3 3 FYVE zinc finger FYVE_2 PF02318.16 OQS04932.1 - 2.5e-06 27.7 33.3 0.0011 19.1 11.3 3.2 3 0 0 3 3 3 3 FYVE-type zinc finger FYVE PF01363.21 OQS04933.1 - 1.3e-09 38.0 23.1 4.7e-07 29.9 14.1 2.3 1 1 1 2 2 2 2 FYVE zinc finger GAF PF01590.26 OQS04933.1 - 0.00019 22.1 0.0 0.00032 21.3 0.0 1.4 1 0 0 1 1 1 1 GAF domain Peptidase_S29 PF02907.15 OQS04933.1 - 0.054 13.2 0.0 0.16 11.7 0.0 1.8 2 0 0 2 2 2 0 Hepatitis C virus NS3 protease Ank_2 PF12796.7 OQS04934.1 - 4.8e-31 107.2 29.2 8.2e-09 35.9 0.6 3.9 1 1 5 6 6 6 6 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OQS04934.1 - 2.8e-18 65.7 13.0 0.06 13.7 0.0 8.3 1 1 7 8 8 8 8 Ankyrin repeats (many copies) Ank_4 PF13637.6 OQS04934.1 - 1.7e-16 60.3 11.8 5.3e-05 23.7 0.3 5.8 2 1 5 7 7 7 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQS04934.1 - 1e-10 40.9 3.4 0.55 11.0 0.0 7.7 8 0 0 8 8 8 1 Ankyrin repeat Ank PF00023.30 OQS04934.1 - 0.00047 20.5 6.6 45 4.7 0.0 6.6 1 1 3 4 4 4 0 Ankyrin repeat DUF5049 PF16468.5 OQS04934.1 - 0.013 15.4 0.2 40 4.2 0.0 4.5 4 1 1 5 5 5 0 Domain of unknown function (DUF5049) Pkinase PF00069.25 OQS04935.1 - 3.7e-47 160.9 0.0 1.1e-45 156.1 0.0 2.1 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQS04935.1 - 5e-46 157.1 0.0 1.7e-44 152.1 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OQS04935.1 - 0.0004 19.3 0.0 0.00064 18.6 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase ASFV_J13L PF05568.11 OQS04935.1 - 0.0017 18.2 0.5 0.0037 17.0 0.5 1.5 1 0 0 1 1 1 1 African swine fever virus J13L protein TMEM154 PF15102.6 OQS04935.1 - 0.018 14.9 0.1 0.033 14.1 0.1 1.3 1 0 0 1 1 1 0 TMEM154 protein family Insulin_TMD PF17870.1 OQS04935.1 - 0.13 12.3 1.4 0.28 11.3 1.4 1.5 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment APH PF01636.23 OQS04935.1 - 0.21 11.5 0.0 0.33 10.8 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family zf_C2HC_14 PF18574.1 OQS04936.1 - 1 9.2 3.9 4.1 7.3 0.4 2.4 2 0 0 2 2 2 0 C2HC Zing finger domain Pkinase_Tyr PF07714.17 OQS04937.1 - 9.2e-60 202.1 0.0 5.7e-47 160.2 0.0 3.5 2 1 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 OQS04937.1 - 7.5e-56 189.4 0.0 5.6e-46 157.1 0.0 3.0 2 1 0 2 2 2 2 Protein kinase domain Pkinase_fungal PF17667.1 OQS04937.1 - 0.018 13.8 0.0 0.028 13.2 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase FNIP PF05725.12 OQS04937.1 - 0.04 14.1 0.8 0.73 10.0 0.1 2.7 2 0 0 2 2 2 0 FNIP Repeat Rhomboid PF01694.22 OQS04937.1 - 0.047 13.7 0.1 0.09 12.8 0.1 1.4 1 0 0 1 1 1 0 Rhomboid family MLANA PF14991.6 OQS04937.1 - 0.13 12.5 0.0 0.31 11.3 0.0 1.6 1 0 0 1 1 1 0 Protein melan-A PX PF00787.24 OQS04938.1 - 2.4e-07 30.7 0.5 4.5e-07 29.9 0.5 1.4 1 1 0 1 1 1 1 PX domain RCC1_2 PF13540.6 OQS04940.1 - 5.3e-39 131.3 50.8 1.1e-08 34.7 4.1 8.3 7 2 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat RCC1 PF00415.18 OQS04940.1 - 2.7e-07 31.1 28.4 0.064 13.9 0.3 8.5 7 2 2 9 9 9 5 Regulator of chromosome condensation (RCC1) repeat Ion_trans PF00520.31 OQS04941.1 - 4.1e-122 406.1 89.5 1.2e-36 126.2 17.2 4.1 4 0 0 4 4 4 4 Ion transport protein PKD_channel PF08016.12 OQS04941.1 - 3.1e-10 39.3 76.7 0.00063 18.5 4.8 9.4 8 2 2 10 10 10 8 Polycystin cation channel GPHH PF16905.5 OQS04941.1 - 6.1e-05 22.7 0.0 0.00012 21.7 0.0 1.5 1 0 0 1 1 1 1 Voltage-dependent L-type calcium channel, IQ-associated 2-Hacid_dh_C PF02826.19 OQS04942.1 - 1.2e-51 174.6 0.0 1.8e-51 174.1 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 OQS04942.1 - 1.2e-28 99.4 0.0 1.7e-28 98.9 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 OQS04942.1 - 6.2e-06 26.5 0.2 1.4e-05 25.3 0.2 1.6 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase ACT PF01842.25 OQS04942.1 - 2.2e-05 24.1 0.4 0.00018 21.2 0.1 2.7 3 1 0 3 3 3 1 ACT domain AdoHcyase_NAD PF00670.21 OQS04942.1 - 0.041 13.9 0.1 0.1 12.7 0.1 1.6 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 3HCDH_N PF02737.18 OQS04942.1 - 0.18 11.7 0.9 3.1 7.7 0.1 2.2 1 1 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Rav1p_C PF12234.8 OQS04943.1 - 6.6e-41 140.4 3.0 1.2e-40 139.7 3.0 1.3 1 0 0 1 1 1 1 RAVE protein 1 C terminal WD40 PF00400.32 OQS04943.1 - 0.0011 19.7 9.1 0.44 11.5 0.3 6.3 6 0 0 6 6 6 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OQS04943.1 - 0.019 15.2 0.0 0.38 11.1 0.0 3.3 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain AAA PF00004.29 OQS04944.1 - 4e-12 46.7 0.0 2e-11 44.5 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 OQS04944.1 - 9e-11 42.4 0.1 1.9e-08 34.9 0.0 2.9 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 OQS04944.1 - 2.1e-08 34.5 0.0 7.1e-08 32.8 0.0 1.9 1 1 1 2 2 2 1 AAA domain AAA_lid_10 PF17872.1 OQS04944.1 - 6.1e-07 29.5 0.1 1.5e-06 28.3 0.1 1.6 1 0 0 1 1 1 1 AAA lid domain PIF1 PF05970.14 OQS04944.1 - 0.0023 17.2 0.0 0.0058 15.8 0.0 1.6 2 0 0 2 2 2 1 PIF1-like helicase AAA_19 PF13245.6 OQS04944.1 - 0.003 17.9 0.0 0.011 16.0 0.0 2.0 1 1 0 1 1 1 1 AAA domain ATPase_2 PF01637.18 OQS04944.1 - 0.028 14.4 0.1 0.1 12.5 0.0 2.0 2 1 0 2 2 2 0 ATPase domain predominantly from Archaea NB-ARC PF00931.22 OQS04944.1 - 0.028 13.6 0.0 0.087 12.0 0.0 1.8 2 0 0 2 2 2 0 NB-ARC domain NACHT PF05729.12 OQS04944.1 - 0.056 13.4 0.1 0.21 11.5 0.1 2.1 1 1 0 1 1 1 0 NACHT domain DUF815 PF05673.13 OQS04944.1 - 0.077 12.1 0.0 0.14 11.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Histone PF00125.24 OQS04945.1 - 9.3e-41 139.3 2.2 9.8e-41 139.2 2.2 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 OQS04945.1 - 1.6e-05 25.2 0.1 2.9e-05 24.4 0.1 1.4 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 OQS04945.1 - 0.00024 21.2 0.2 0.00038 20.5 0.2 1.3 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CBFD_NFYB_HMF PF00808.23 OQS04945.1 - 0.0017 18.6 0.0 0.0029 17.9 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 OQS04945.1 - 0.031 14.4 0.1 0.044 13.9 0.1 1.3 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 OQS04945.1 - 0.034 14.1 0.1 0.054 13.5 0.1 1.3 1 0 0 1 1 1 0 Bromodomain associated Histone_H2A_C PF16211.5 OQS04946.1 - 6.5e-19 67.4 1.4 6.5e-19 67.4 1.4 1.9 2 0 0 2 2 2 1 C-terminus of histone H2A Histone PF00125.24 OQS04946.1 - 4.1e-16 59.5 0.0 6e-16 59.0 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 OQS04946.1 - 0.00014 22.1 0.0 0.00022 21.5 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 OQS04947.1 - 4.6e-20 72.3 0.2 5.6e-20 72.0 0.2 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID_20kDa PF03847.13 OQS04947.1 - 0.00021 21.7 0.0 0.00036 21.0 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A CBFD_NFYB_HMF PF00808.23 OQS04947.1 - 0.0016 18.7 0.0 0.0034 17.6 0.0 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone YscO-like PF16789.5 OQS04947.1 - 0.0087 16.1 0.1 0.01 15.9 0.1 1.1 1 0 0 1 1 1 1 YscO-like protein RCC1 PF00415.18 OQS04948.1 - 2.8e-62 207.1 20.4 8.1e-14 52.0 0.0 8.2 8 0 0 8 8 8 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 OQS04948.1 - 3.4e-28 96.8 38.4 1.6e-05 24.6 0.2 7.5 6 1 0 6 6 6 6 Regulator of chromosome condensation (RCC1) repeat BTB PF00651.31 OQS04948.1 - 8e-19 67.9 0.1 3e-09 37.1 0.1 3.4 3 0 0 3 3 3 2 BTB/POZ domain SBBP PF06739.11 OQS04948.1 - 0.0081 16.1 0.9 3.5 7.7 0.3 2.9 3 0 0 3 3 3 2 Beta-propeller repeat Nipped-B_C PF12830.7 OQS04949.1 - 2.7e-42 144.9 3.2 3.1e-40 138.2 0.3 3.7 3 0 0 3 3 3 1 Sister chromatid cohesion C-terminus Cohesin_HEAT PF12765.7 OQS04949.1 - 1.2e-08 35.1 3.0 7.6e-06 26.1 0.1 3.1 2 0 0 2 2 2 2 HEAT repeat associated with sister chromatid cohesion HEAT_2 PF13646.6 OQS04949.1 - 0.00014 22.2 1.0 4 7.9 0.0 4.8 4 1 0 4 4 4 2 HEAT repeats Cnd1 PF12717.7 OQS04949.1 - 0.00081 19.5 9.6 0.23 11.5 1.4 4.8 5 1 0 5 5 5 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 OQS04949.1 - 0.0054 16.9 1.1 70 4.1 0.0 5.7 5 0 0 5 5 5 0 HEAT repeat HBD PF18534.1 OQS04949.1 - 0.032 14.4 5.8 36 4.6 0.5 4.5 3 1 1 4 4 4 0 Helical bundle domain MSP7_C PF12948.7 OQS04949.1 - 0.42 11.3 1.6 1.7 9.3 0.2 2.6 3 0 0 3 3 3 0 MSP7-like protein C-terminal domain PT PF04886.12 OQS04950.1 - 2.3 7.8 131.2 0.13 11.9 19.7 8.0 3 3 0 3 3 3 0 PT repeat Fer4_21 PF14697.6 OQS04950.1 - 4.4 7.5 29.6 32 4.8 0.0 6.9 7 0 0 7 7 7 0 4Fe-4S dicluster domain Fer4_6 PF12837.7 OQS04950.1 - 9.8 6.4 23.5 41 4.5 0.7 6.8 6 0 0 6 6 6 0 4Fe-4S binding domain Pcc1 PF09341.10 OQS04951.1 - 8.8e-15 54.6 0.1 1.1e-14 54.3 0.1 1.0 1 0 0 1 1 1 1 Transcription factor Pcc1 CH PF00307.31 OQS04953.1 - 1.9e-14 53.8 0.1 2.7e-14 53.3 0.1 1.2 1 0 0 1 1 1 1 Calponin homology (CH) domain CDC24 PF06395.11 OQS04953.1 - 0.049 13.9 0.1 0.1 12.9 0.1 1.5 1 0 0 1 1 1 0 CDC24 Calponin CPSF73-100_C PF11718.8 OQS04954.1 - 4.8e-36 124.3 1.4 4.7e-35 121.1 1.5 2.3 2 0 0 2 2 2 1 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term Beta-Casp PF10996.8 OQS04954.1 - 1.2e-30 106.0 0.0 4.4e-30 104.2 0.0 2.0 2 0 0 2 2 2 1 Beta-Casp domain Lactamase_B_6 PF16661.5 OQS04954.1 - 1.8e-22 79.8 0.0 4.3e-22 78.5 0.0 1.6 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily domain Lactamase_B PF00753.27 OQS04954.1 - 6e-19 68.8 0.1 1.3e-18 67.8 0.1 1.5 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily RMMBL PF07521.12 OQS04954.1 - 1.7e-16 59.9 0.0 4.8e-16 58.4 0.0 1.8 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain Lactamase_B_2 PF12706.7 OQS04954.1 - 2.8e-09 36.8 0.2 7.4e-09 35.4 0.2 1.7 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Beta_lactamase3 PF17030.5 OQS04954.1 - 1.8e-05 24.1 0.0 3.7e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 Putative beta-lactamase-like family Lactamase_B_3 PF13483.6 OQS04954.1 - 3.7e-05 23.7 0.0 0.00015 21.7 0.0 2.0 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Abhydrolase_6 PF12697.7 OQS04956.1 - 0.00018 22.2 0.0 0.79 10.3 0.0 2.7 2 1 0 2 2 2 2 Alpha/beta hydrolase family Thioesterase PF00975.20 OQS04956.1 - 0.0047 17.1 0.0 1.7 8.7 0.0 2.4 2 0 0 2 2 2 2 Thioesterase domain Hydrolase_4 PF12146.8 OQS04956.1 - 0.0068 15.7 0.0 4.2 6.6 0.0 2.4 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Imm21 PF15589.6 OQS04956.1 - 0.027 14.5 0.1 11 6.1 0.0 2.4 2 0 0 2 2 2 0 Immunity protein 21 DUF5113 PF17140.4 OQS04957.1 - 0.026 14.4 0.0 0.039 13.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5113) RRM_1 PF00076.22 OQS04958.1 - 6.5e-13 48.3 0.6 1.6e-07 31.0 0.1 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 OQS04958.1 - 8.7e-08 32.0 0.2 0.004 17.1 0.0 2.3 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif PWI PF01480.17 OQS04958.1 - 1.5e-06 28.4 0.0 4.5e-06 26.9 0.0 1.8 1 0 0 1 1 1 1 PWI domain RRM_occluded PF16842.5 OQS04958.1 - 0.00014 21.7 0.0 0.005 16.7 0.0 2.4 2 0 0 2 2 2 1 Occluded RNA-recognition motif RRM_5 PF13893.6 OQS04958.1 - 0.055 13.1 0.0 0.16 11.5 0.0 1.8 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RNA_bind PF08675.11 OQS04958.1 - 0.08 13.0 0.2 0.39 10.8 0.0 2.1 2 0 0 2 2 2 0 RNA binding domain Exonuc_VII_L PF02601.15 OQS04958.1 - 1.4 8.4 13.5 0.31 10.6 7.8 2.3 3 0 0 3 3 3 0 Exonuclease VII, large subunit AAA_23 PF13476.6 OQS04958.1 - 2.4 8.6 12.8 1.1 9.7 8.7 2.1 2 0 0 2 2 2 0 AAA domain HSP70 PF00012.20 OQS04958.1 - 3.3 5.8 7.9 5.4 5.1 7.9 1.3 1 0 0 1 1 1 0 Hsp70 protein HOOK PF05622.12 OQS04958.1 - 3.9 5.5 25.1 0.024 12.8 16.8 1.4 2 0 0 2 2 2 0 HOOK protein Ank_2 PF12796.7 OQS04959.1 - 3.3e-15 56.4 0.4 8.8e-15 55.1 0.4 1.6 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQS04959.1 - 1.3e-13 51.1 0.4 1.1e-07 32.3 0.0 3.0 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 OQS04959.1 - 1.7e-11 44.0 1.5 4e-05 23.9 0.2 3.1 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.6 OQS04959.1 - 2e-11 43.1 0.0 0.011 16.2 0.0 3.2 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.6 OQS04959.1 - 3.9e-07 30.2 0.2 0.0095 16.2 0.0 2.8 1 1 2 3 3 3 3 Ankyrin repeats (many copies) RNase_H2-Ydr279 PF09468.10 OQS04960.1 - 8.5e-06 26.0 0.2 1.3e-05 25.4 0.2 1.2 1 0 0 1 1 1 1 Ydr279p protein family (RNase H2 complex component) wHTH domain DUF719 PF05334.13 OQS04960.1 - 0.076 13.2 1.3 0.094 12.9 0.2 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF719) PcfK PF14058.6 OQS04960.1 - 0.36 11.1 3.4 13 6.1 0.2 2.2 2 0 0 2 2 2 0 PcfK-like protein ATP-synt_ab PF00006.25 OQS04961.1 - 5.8e-105 349.6 0.0 8.3e-105 349.1 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_Xtn PF16886.5 OQS04961.1 - 1.7e-38 131.1 0.0 3.1e-38 130.4 0.0 1.4 1 0 0 1 1 1 1 ATPsynthase alpha/beta subunit N-term extension ATP-synt_ab_N PF02874.23 OQS04961.1 - 2.2e-14 53.7 1.6 3.5e-14 53.1 0.3 2.1 2 0 0 2 2 2 1 ATP synthase alpha/beta family, beta-barrel domain AAA_18 PF13238.6 OQS04961.1 - 0.11 13.1 0.1 0.32 11.5 0.0 1.8 2 0 0 2 2 2 0 AAA domain DOT1 PF08123.13 OQS04963.1 - 1.1e-13 51.3 0.1 3.1e-12 46.5 0.1 2.2 1 1 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_31 PF13847.6 OQS04963.1 - 8.5e-07 28.9 0.0 1.4e-06 28.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 OQS04963.1 - 0.0004 19.9 0.0 0.00078 19.0 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_25 PF13649.6 OQS04963.1 - 0.012 16.3 0.0 0.029 15.1 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_2 PF00891.18 OQS04963.1 - 0.025 13.9 0.0 0.033 13.5 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase domain MTS PF05175.14 OQS04963.1 - 0.026 14.1 0.0 0.15 11.6 0.0 2.0 1 1 0 1 1 1 0 Methyltransferase small domain PCMT PF01135.19 OQS04963.1 - 0.045 13.5 0.0 0.075 12.8 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Pkinase_Tyr PF07714.17 OQS04964.1 - 9.1e-48 162.8 0.0 6.9e-43 146.8 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 OQS04964.1 - 3.1e-43 148.1 0.1 1.7e-37 129.2 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Haspin_kinase PF12330.8 OQS04964.1 - 0.025 13.5 0.5 0.076 12.0 0.0 1.8 2 0 0 2 2 2 0 Haspin like kinase domain Pkinase_fungal PF17667.1 OQS04964.1 - 0.073 11.8 0.1 0.14 10.9 0.1 1.4 2 0 0 2 2 2 0 Fungal protein kinase Kdo PF06293.14 OQS04964.1 - 0.08 12.3 0.1 0.12 11.7 0.1 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family C2 PF00168.30 OQS04966.1 - 1.9e-13 50.6 0.1 4.6e-05 23.7 0.1 3.6 3 0 0 3 3 3 3 C2 domain SH2 PF00017.24 OQS04966.1 - 0.002 18.2 0.0 0.0089 16.1 0.0 2.2 2 0 0 2 2 2 1 SH2 domain TPR_8 PF13181.6 OQS04966.1 - 3.1 8.2 7.3 4 7.9 0.1 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat Thioredoxin PF00085.20 OQS04967.1 - 1.6e-09 37.7 0.0 1.9e-09 37.4 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin TPR_19 PF14559.6 OQS04968.1 - 0.00097 19.6 1.2 5 7.7 0.0 4.1 3 1 1 4 4 4 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 OQS04968.1 - 0.0029 17.7 0.4 3.6 7.7 0.0 2.7 2 0 0 2 2 2 2 Fis1 C-terminal tetratricopeptide repeat TPR_14 PF13428.6 OQS04968.1 - 0.0072 17.1 1.0 5.2 8.2 0.1 4.2 5 0 0 5 5 5 1 Tetratricopeptide repeat PLDc_2 PF13091.6 OQS04968.1 - 0.02 14.8 0.3 0.069 13.0 0.1 2.0 2 0 0 2 2 2 0 PLD-like domain ComZ PF10815.8 OQS04968.1 - 0.037 14.0 1.6 1.7 8.7 0.0 3.1 3 0 0 3 3 3 0 ComZ TPR_8 PF13181.6 OQS04968.1 - 0.067 13.4 2.8 0.59 10.5 0.2 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat OHCU_decarbox PF09349.10 OQS04968.1 - 0.11 13.0 0.3 24 5.4 0.2 2.6 2 0 0 2 2 2 0 OHCU decarboxylase TPR_6 PF13174.6 OQS04968.1 - 0.13 13.0 0.3 4.9 8.0 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 OQS04968.1 - 2.5 8.4 5.8 20 5.6 0.5 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat Methyltransf_25 PF13649.6 OQS04969.1 - 6.7e-10 39.5 0.0 9.3e-10 39.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain DOT1 PF08123.13 OQS04969.1 - 4e-08 33.0 0.1 9.6e-07 28.5 0.1 2.0 1 1 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_31 PF13847.6 OQS04969.1 - 1.4e-07 31.5 0.0 1.8e-07 31.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 OQS04969.1 - 2.7e-07 30.2 0.0 3.1e-07 30.0 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_11 PF08241.12 OQS04969.1 - 2.4e-06 28.1 0.0 3.3e-06 27.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_15 PF09445.10 OQS04969.1 - 3.1e-06 26.9 0.0 4.1e-06 26.5 0.0 1.1 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase RrnaAD PF00398.20 OQS04969.1 - 1e-05 24.8 0.0 1.3e-05 24.4 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_32 PF13679.6 OQS04969.1 - 4.9e-05 23.4 0.0 6.2e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 OQS04969.1 - 7.1e-05 22.3 0.0 8.8e-05 22.0 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_18 PF12847.7 OQS04969.1 - 0.00015 21.8 0.1 0.00022 21.2 0.1 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OQS04969.1 - 0.00044 20.1 0.0 0.00053 19.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OQS04969.1 - 0.00053 20.7 0.0 0.00074 20.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 OQS04969.1 - 0.0012 18.4 0.0 0.0015 18.0 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase TehB PF03848.14 OQS04969.1 - 0.0027 17.2 0.0 0.0036 16.7 0.0 1.1 1 0 0 1 1 1 1 Tellurite resistance protein TehB MetW PF07021.12 OQS04969.1 - 0.0034 17.0 0.0 0.0043 16.7 0.0 1.2 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW MTS PF05175.14 OQS04969.1 - 0.0044 16.6 0.0 0.0061 16.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain PCMT PF01135.19 OQS04969.1 - 0.0091 15.8 0.0 0.014 15.2 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) N6_N4_Mtase PF01555.18 OQS04969.1 - 0.082 12.6 0.0 0.1 12.3 0.0 1.2 1 0 0 1 1 1 0 DNA methylase Ham1p_like PF01725.16 OQS04970.1 - 1.6e-49 168.4 0.0 2.6e-49 167.7 0.0 1.3 1 0 0 1 1 1 1 Ham1 family Kinesin PF00225.23 OQS04970.1 - 1.2e-22 80.3 0.0 1.8e-22 79.7 0.0 1.2 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 OQS04970.1 - 0.0027 17.7 0.0 0.006 16.5 0.0 1.6 1 0 0 1 1 1 1 Microtubule binding LINES_N PF14694.6 OQS04970.1 - 0.022 14.2 1.2 0.065 12.7 0.9 1.8 1 1 1 2 2 2 0 Lines N-terminus FHA PF00498.26 OQS04970.1 - 0.12 12.7 0.0 0.77 10.2 0.0 2.3 2 0 0 2 2 2 0 FHA domain Peptidase_M13_N PF05649.13 OQS04971.1 - 3.7e-79 267.2 0.1 4.7e-79 266.8 0.1 1.1 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13 PF01431.21 OQS04971.1 - 2e-66 223.5 0.7 2.7e-66 223.1 0.1 1.6 2 0 0 2 2 2 1 Peptidase family M13 Peptidase_M48 PF01435.18 OQS04971.1 - 0.054 13.3 0.1 0.13 12.0 0.1 1.6 2 0 0 2 2 2 0 Peptidase family M48 Myb_DNA-binding PF00249.31 OQS04972.1 - 1.8e-08 34.4 0.1 2.8e-08 33.8 0.1 1.3 1 0 0 1 1 1 1 Myb-like DNA-binding domain CAP_GLY PF01302.25 OQS04973.1 - 3.9e-24 84.4 1.0 7.2e-24 83.6 1.0 1.5 1 0 0 1 1 1 1 CAP-Gly domain CLASP_N PF12348.8 OQS04973.1 - 2.1e-21 76.6 0.5 3e-21 76.0 0.5 1.2 1 0 0 1 1 1 1 CLASP N terminal Nop14 PF04147.12 OQS04973.1 - 0.0031 15.8 9.0 0.0047 15.2 9.0 1.3 1 0 0 1 1 1 1 Nop14-like family SDA1 PF05285.12 OQS04973.1 - 0.0036 16.8 9.4 0.0048 16.4 9.4 1.2 1 0 0 1 1 1 1 SDA1 Presenilin PF01080.17 OQS04973.1 - 0.026 13.3 1.2 0.033 13.0 1.2 1.3 1 0 0 1 1 1 0 Presenilin CPSF100_C PF13299.6 OQS04973.1 - 0.043 14.0 3.5 0.089 13.0 3.5 1.5 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal DDHD PF02862.17 OQS04973.1 - 0.052 13.7 0.5 0.068 13.3 0.5 1.2 1 0 0 1 1 1 0 DDHD domain CobT PF06213.12 OQS04973.1 - 0.057 12.8 16.2 0.11 11.9 16.2 1.4 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Pox_Ag35 PF03286.14 OQS04973.1 - 0.18 11.6 9.0 0.31 10.8 9.0 1.4 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Myc_N PF01056.18 OQS04973.1 - 0.26 11.2 8.9 0.36 10.7 8.9 1.2 1 0 0 1 1 1 0 Myc amino-terminal region DUF4820 PF16091.5 OQS04973.1 - 0.45 9.8 6.0 0.68 9.3 6.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) NOA36 PF06524.12 OQS04973.1 - 0.52 9.6 12.7 0.76 9.0 12.7 1.2 1 0 0 1 1 1 0 NOA36 protein Ureide_permease PF07168.11 OQS04973.1 - 0.72 8.5 2.6 0.74 8.5 1.3 1.6 2 0 0 2 2 2 0 Ureide permease Auts2 PF15336.6 OQS04973.1 - 1.7 8.7 3.9 2.9 8.0 3.9 1.3 1 0 0 1 1 1 0 Autism susceptibility gene 2 protein RNA_pol_Rpc4 PF05132.14 OQS04973.1 - 2 8.8 6.3 3.4 8.1 6.3 1.3 1 0 0 1 1 1 0 RNA polymerase III RPC4 Paf1 PF03985.13 OQS04973.1 - 4.9 6.0 16.7 7.1 5.5 16.7 1.1 1 0 0 1 1 1 0 Paf1 TRAP_alpha PF03896.16 OQS04973.1 - 7.4 5.7 11.3 11 5.1 11.3 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Zip PF02535.22 OQS04973.1 - 9.9 5.3 8.3 15 4.7 8.3 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter zf-Tim10_DDP PF02953.15 OQS04974.1 - 2.2e-13 49.6 0.1 3.2e-13 49.1 0.1 1.3 1 0 0 1 1 1 1 Tim10/DDP family zinc finger GAS PF13851.6 OQS04975.1 - 2.3e-74 249.1 26.3 2.3e-74 249.1 26.3 3.3 2 1 1 3 3 3 1 Growth-arrest specific micro-tubule binding PET117 PF15786.5 OQS04975.1 - 0.0053 17.0 3.4 0.0053 17.0 3.4 5.1 4 2 0 4 4 4 1 PET assembly of cytochrome c oxidase, mitochondrial Ank_2 PF12796.7 OQS04976.1 - 2.3e-14 53.7 1.0 1.3e-07 32.1 0.1 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OQS04976.1 - 1.6e-10 40.3 0.8 0.0049 17.3 0.0 3.7 3 1 0 3 3 3 2 Ankyrin repeat Ank PF00023.30 OQS04976.1 - 5.1e-08 33.0 0.8 0.14 12.7 0.0 3.5 3 0 0 3 3 3 3 Ankyrin repeat Ank_4 PF13637.6 OQS04976.1 - 5e-07 30.1 3.5 0.0002 21.8 0.1 2.5 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 OQS04976.1 - 8.7e-07 29.1 0.1 3.9e-06 27.0 0.0 2.1 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Peptidase_C69 PF03577.15 OQS04977.1 - 5.3e-43 147.4 0.3 1.9e-42 145.6 0.3 1.9 1 1 0 1 1 1 1 Peptidase family C69 DUF2085 PF09858.9 OQS04978.1 - 0.024 15.1 0.4 0.043 14.3 0.4 1.4 1 1 0 1 1 1 0 Predicted membrane protein (DUF2085) HTH_Tnp_Tc5 PF03221.16 OQS04979.1 - 3.1e-10 39.9 0.0 5.5e-10 39.1 0.0 1.4 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain CENP-B_N PF04218.13 OQS04979.1 - 3.7e-08 32.9 0.6 6.1e-08 32.2 0.6 1.4 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain HTH_23 PF13384.6 OQS04979.1 - 1.1e-05 25.1 0.0 2.9e-05 23.7 0.0 1.7 1 0 0 1 1 1 1 Homeodomain-like domain SRC-1 PF08832.10 OQS04979.1 - 0.0045 18.0 0.0 0.014 16.5 0.0 1.8 1 0 0 1 1 1 1 Steroid receptor coactivator HTH_7 PF02796.15 OQS04979.1 - 0.0055 16.8 0.0 0.012 15.6 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain of resolvase HTH_28 PF13518.6 OQS04979.1 - 0.0098 16.0 0.0 0.029 14.5 0.0 1.8 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_3 PF01381.22 OQS04979.1 - 0.029 14.4 0.1 0.32 11.1 0.1 2.3 1 1 1 2 2 2 0 Helix-turn-helix HTH_29 PF13551.6 OQS04979.1 - 0.065 13.3 0.0 0.15 12.1 0.0 1.6 1 0 0 1 1 1 0 Winged helix-turn helix EF-hand_1 PF00036.32 OQS04980.1 - 1.4e-28 96.3 18.6 1.2e-06 27.6 0.0 6.4 7 0 0 7 7 7 5 EF hand Metallophos PF00149.28 OQS04980.1 - 7.2e-28 98.5 0.1 1.4e-27 97.6 0.1 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase EF-hand_7 PF13499.6 OQS04980.1 - 7.3e-27 93.6 15.0 2.8e-11 43.7 3.0 4.9 5 0 0 5 5 5 3 EF-hand domain pair EF-hand_6 PF13405.6 OQS04980.1 - 5.1e-26 88.3 13.1 2.2e-06 27.1 0.0 7.1 7 0 0 7 7 7 5 EF-hand domain EF-hand_8 PF13833.6 OQS04980.1 - 1.5e-24 85.6 15.0 5.9e-08 32.5 0.6 6.1 5 2 2 7 7 6 5 EF-hand domain pair EF-hand_5 PF13202.6 OQS04980.1 - 1.4e-19 68.6 15.0 2.9e-05 23.4 0.1 5.6 5 0 0 5 5 5 4 EF hand PPP5 PF08321.12 OQS04980.1 - 4e-10 39.8 0.1 2.6e-09 37.3 0.0 2.5 2 0 0 2 2 2 1 PPP5 TPR repeat region EF-hand_11 PF08976.11 OQS04980.1 - 3.6e-09 37.4 4.0 0.071 14.0 0.1 4.1 2 2 2 4 4 4 3 EF-hand domain EF-hand_9 PF14658.6 OQS04980.1 - 1.9e-06 28.1 0.7 0.017 15.4 0.1 3.4 3 0 0 3 3 3 2 EF-hand domain SPARC_Ca_bdg PF10591.9 OQS04980.1 - 5e-06 26.8 6.1 0.058 13.7 0.0 4.5 5 0 0 5 5 5 2 Secreted protein acidic and rich in cysteine Ca binding region CAP_GLY PF01302.25 OQS04980.1 - 7.2e-06 25.9 0.2 6.2e-05 22.9 0.0 2.6 3 0 0 3 3 3 1 CAP-Gly domain EF-hand_4 PF12763.7 OQS04980.1 - 1.6e-05 24.8 5.4 0.0024 17.8 0.7 4.1 4 2 0 4 4 3 1 Cytoskeletal-regulatory complex EF hand IQ PF00612.27 OQS04980.1 - 0.028 14.2 0.3 0.07 13.0 0.3 1.7 1 0 0 1 1 1 0 IQ calmodulin-binding motif EF-hand_14 PF17959.1 OQS04980.1 - 0.055 13.8 0.8 1.9 8.9 0.1 3.3 3 0 0 3 3 3 0 EF-hand domain Caleosin PF05042.13 OQS04980.1 - 0.093 12.7 0.4 8.2 6.3 0.0 3.5 3 0 0 3 3 3 0 Caleosin related protein EF-hand_10 PF14788.6 OQS04980.1 - 0.92 9.4 4.6 0.97 9.3 0.2 3.2 4 0 0 4 4 4 0 EF hand Clathrin PF00637.20 OQS04982.1 - 5.7e-187 613.1 30.7 7.6e-32 110.1 1.0 8.2 8 0 0 8 8 8 7 Region in Clathrin and VPS Clathrin_H_link PF13838.6 OQS04982.1 - 2.8e-25 88.0 0.1 9.4e-25 86.3 0.1 2.0 1 0 0 1 1 1 1 Clathrin-H-link Clathrin_propel PF01394.20 OQS04982.1 - 4.5e-17 61.4 0.0 8.2e-08 32.2 0.0 5.4 5 0 0 5 5 5 3 Clathrin propeller repeat Clathrin-link PF09268.10 OQS04982.1 - 1.7e-05 24.1 0.0 6.4e-05 22.2 0.0 2.1 1 0 0 1 1 1 1 Clathrin, heavy-chain linker TPR_7 PF13176.6 OQS04982.1 - 0.00029 20.6 4.9 18 5.7 0.0 6.9 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_14 PF13428.6 OQS04982.1 - 0.00091 19.9 11.4 88 4.3 0.1 9.2 10 0 0 10 10 10 0 Tetratricopeptide repeat TPR_1 PF00515.28 OQS04982.1 - 0.0013 18.5 4.2 1.7 8.6 0.1 5.3 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.17 OQS04982.1 - 0.0028 17.7 5.8 1.9 8.8 0.1 5.2 4 0 0 4 4 4 1 Tetratricopeptide repeat ANAPC3 PF12895.7 OQS04982.1 - 0.018 15.3 2.6 1 9.6 0.0 3.9 4 0 0 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 Coatomer_WDAD PF04053.14 OQS04982.1 - 0.037 13.1 3.2 0.84 8.6 0.0 3.3 4 0 0 4 4 4 0 Coatomer WD associated region ARL2_Bind_BART PF11527.8 OQS04983.1 - 1.6e-21 76.5 0.0 6.4e-21 74.6 0.0 2.1 1 0 0 1 1 1 1 The ARF-like 2 binding protein BART WW PF00397.26 OQS04983.1 - 2.6e-08 33.8 3.3 5e-08 32.9 3.3 1.5 1 0 0 1 1 1 1 WW domain BLOC1S3 PF15753.5 OQS04983.1 - 0.0024 18.0 0.3 0.0024 18.0 0.3 2.4 2 1 1 3 3 3 1 Biogenesis of lysosome-related organelles complex 1 subunit 3 Hydin_ADK PF17213.3 OQS04983.1 - 0.27 11.5 5.9 2.6 8.3 0.1 2.6 2 0 0 2 2 2 0 Hydin Adenylate kinase-like domain NTPase_I-T PF01931.18 OQS04984.1 - 1.5e-111 369.5 0.0 3e-58 196.2 0.1 2.0 2 0 0 2 2 2 2 Protein of unknown function DUF84 CSRNP_N PF16019.5 OQS04985.1 - 0.026 14.5 0.0 0.034 14.1 0.0 1.3 1 1 0 1 1 1 0 Cysteine/serine-rich nuclear protein N-terminus DUF373 PF04123.13 OQS04987.1 - 0.74 9.2 21.0 0.42 10.0 7.9 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF373) PreAtp-grasp PF18604.1 OQS04988.1 - 0.065 12.9 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 Pre ATP-grasp domain FA_hydroxylase PF04116.13 OQS04989.1 - 9.3e-06 26.0 29.6 3.9e-05 24.0 19.5 2.6 2 2 0 2 2 2 2 Fatty acid hydroxylase superfamily Pkinase PF00069.25 OQS04991.1 - 1.3e-66 224.7 0.1 1.5e-66 224.4 0.1 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQS04991.1 - 1.5e-21 76.9 0.0 2.1e-21 76.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 OQS04991.1 - 6.3e-08 32.8 0.0 4e-05 23.7 0.2 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 OQS04991.1 - 0.00076 18.4 0.1 0.0046 15.8 0.0 1.9 2 0 0 2 2 2 1 Fungal protein kinase Kdo PF06293.14 OQS04991.1 - 0.0061 15.9 0.5 0.013 14.9 0.5 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 OQS04991.1 - 0.033 13.8 0.4 0.061 12.9 0.4 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase RIO1 PF01163.22 OQS04991.1 - 0.051 13.2 0.2 0.11 12.0 0.2 1.5 1 1 0 1 1 1 0 RIO1 family DUF2459 PF09601.10 OQS04991.1 - 0.15 11.8 0.0 0.39 10.5 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2459) CBM_1 PF00734.18 OQS04992.1 - 0.0031 17.5 11.4 0.0031 17.5 11.4 3.7 4 0 0 4 4 4 2 Fungal cellulose binding domain IMS_C PF11799.8 OQS04993.1 - 0.00012 22.8 0.0 0.0002 22.0 0.0 1.4 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain IMS PF00817.20 OQS04993.1 - 0.00015 21.8 0.2 0.00046 20.2 0.1 1.7 2 0 0 2 2 2 1 impB/mucB/samB family ALO PF04030.14 OQS04994.1 - 3e-19 69.9 3.2 3.4e-18 66.4 3.2 2.2 1 1 0 1 1 1 1 D-arabinono-1,4-lactone oxidase FAD_binding_4 PF01565.23 OQS04994.1 - 8.7e-18 64.4 2.9 1.9e-17 63.3 2.9 1.6 1 0 0 1 1 1 1 FAD binding domain Metallophos PF00149.28 OQS04994.1 - 9.6e-16 58.9 0.9 2.2e-15 57.7 0.9 1.6 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_C PF14008.6 OQS04994.1 - 9.9e-06 26.3 0.7 2.9e-05 24.8 0.7 1.9 1 0 0 1 1 1 1 Iron/zinc purple acid phosphatase-like protein C Pur_ac_phosph_N PF16656.5 OQS04994.1 - 0.00017 22.1 1.0 0.00043 20.8 1.0 1.7 1 0 0 1 1 1 1 Purple acid Phosphatase, N-terminal domain Metallophos_2 PF12850.7 OQS04994.1 - 0.00033 20.9 0.0 0.0056 16.9 0.0 2.4 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Pkinase_Tyr PF07714.17 OQS04995.1 - 9.3e-46 156.2 0.2 3.2e-31 108.6 0.0 2.0 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 OQS04995.1 - 3.5e-44 151.1 0.0 4.7e-44 150.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 OQS04995.1 - 2.6e-05 23.7 0.0 3.4e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 OQS04995.1 - 0.00013 20.9 0.0 0.00018 20.4 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 OQS04995.1 - 0.00029 20.3 0.0 0.00042 19.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Choline_kinase PF01633.20 OQS04995.1 - 0.0003 20.4 0.0 0.17 11.4 0.0 2.2 1 1 1 2 2 2 2 Choline/ethanolamine kinase APH PF01636.23 OQS04995.1 - 0.00091 19.2 0.0 0.0013 18.7 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family FTA2 PF13095.6 OQS04995.1 - 0.2 11.2 0.5 0.58 9.7 0.3 1.9 1 1 1 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Ank_2 PF12796.7 OQS04996.1 - 6.5e-57 190.1 14.6 4.3e-16 59.3 0.3 3.8 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQS04996.1 - 2.2e-40 136.5 12.7 1.6e-12 47.6 0.1 5.2 1 1 5 6 6 6 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQS04996.1 - 3.5e-33 109.9 3.4 2e-05 24.6 0.0 6.6 7 0 0 7 7 7 6 Ankyrin repeat Ank PF00023.30 OQS04996.1 - 2.2e-30 103.8 13.7 1.1e-05 25.6 0.1 6.2 5 1 1 6 6 6 5 Ankyrin repeat Ank_5 PF13857.6 OQS04996.1 - 6.7e-28 96.4 9.4 9.4e-09 35.4 0.0 5.3 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Shigella_OspC PF06128.11 OQS04996.1 - 0.032 14.0 0.1 9.6 5.8 0.0 2.9 2 1 2 4 4 4 0 Shigella flexneri OspC protein cobW PF02492.19 OQS04997.1 - 4.3e-43 146.9 0.2 6.7e-43 146.3 0.2 1.3 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.14 OQS04997.1 - 6.6e-17 61.2 0.0 1.3e-16 60.3 0.0 1.5 1 0 0 1 1 1 1 Cobalamin synthesis protein cobW C-terminal domain RsgA_GTPase PF03193.16 OQS04997.1 - 0.00085 19.3 0.6 0.2 11.6 0.1 2.6 2 1 0 2 2 2 1 RsgA GTPase T2SSE PF00437.20 OQS04997.1 - 0.0027 16.8 0.0 0.005 15.9 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_29 PF13555.6 OQS04997.1 - 0.0029 17.3 0.1 0.0071 16.1 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.6 OQS04997.1 - 0.01 16.1 0.0 0.027 14.7 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 OQS04997.1 - 0.014 15.8 0.0 0.031 14.6 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain TsaE PF02367.17 OQS04997.1 - 0.023 14.7 0.0 0.043 13.8 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE MeaB PF03308.16 OQS04997.1 - 0.023 13.7 2.1 0.2 10.6 2.1 2.4 1 1 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_23 PF13476.6 OQS04997.1 - 0.025 15.1 0.5 0.051 14.1 0.1 1.7 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 OQS04997.1 - 0.05 13.3 0.1 0.2 11.4 0.0 1.9 2 0 0 2 2 2 0 AAA domain TPKR_C2 PF16920.5 OQS04997.1 - 0.051 13.7 0.1 0.1 12.8 0.1 1.5 1 0 0 1 1 1 0 Tyrosine-protein kinase receptor C2 Ig-like domain ABC_tran PF00005.27 OQS04997.1 - 0.069 13.7 0.0 0.13 12.8 0.0 1.7 1 0 0 1 1 1 0 ABC transporter ATP_bind_1 PF03029.17 OQS04997.1 - 0.1 12.4 0.7 15 5.3 0.0 2.6 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein MobB PF03205.14 OQS04997.1 - 0.1 12.5 0.0 0.23 11.4 0.0 1.7 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B MMR_HSR1 PF01926.23 OQS04997.1 - 0.12 12.4 0.2 0.98 9.5 0.2 2.3 1 1 0 1 1 1 0 50S ribosome-binding GTPase LRR_4 PF12799.7 OQS04998.1 - 5.1e-10 39.4 6.2 7.5e-05 23.0 0.4 4.2 1 1 2 3 3 3 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 OQS04998.1 - 9.1e-09 35.0 7.6 1.1e-05 25.1 1.6 3.8 1 1 1 2 2 2 2 Leucine rich repeat GIT_CC PF16559.5 OQS04998.1 - 0.013 15.3 1.8 0.013 15.3 1.8 6.9 6 2 1 7 7 7 0 GIT coiled-coil Rho guanine nucleotide exchange factor LRR_6 PF13516.6 OQS04998.1 - 0.021 14.8 6.3 12 6.2 0.4 5.4 5 0 0 5 5 5 0 Leucine Rich repeat LRR_1 PF00560.33 OQS04998.1 - 1.1 10.1 5.4 67 4.6 0.4 4.7 4 1 0 4 4 4 0 Leucine Rich Repeat Tropomyosin PF00261.20 OQS04998.1 - 2 7.7 103.6 0.34 10.2 31.5 5.4 1 1 4 5 5 5 0 Tropomyosin Lectin_N PF03954.14 OQS04999.1 - 3.3 7.5 10.5 4.3 7.1 7.0 2.8 2 1 0 2 2 2 0 Hepatic lectin, N-terminal domain Pkinase PF00069.25 OQS05000.1 - 2.1e-64 217.5 0.0 2.4e-64 217.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQS05000.1 - 3.1e-35 121.7 0.0 4.2e-35 121.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OQS05000.1 - 3.7e-14 52.7 0.1 4.6e-12 45.8 0.0 2.1 1 1 1 2 2 2 2 Kinase-like Pkinase_fungal PF17667.1 OQS05000.1 - 1.4e-06 27.4 0.1 1.8e-06 27.0 0.1 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 OQS05000.1 - 1.1e-05 25.5 0.3 0.00047 20.2 0.2 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 OQS05000.1 - 1.9e-05 24.1 1.0 2.8e-05 23.6 1.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 OQS05000.1 - 5.4e-05 22.3 0.3 6.9e-05 21.9 0.3 1.2 1 0 0 1 1 1 1 Haspin like kinase domain FTA2 PF13095.6 OQS05000.1 - 0.0003 20.5 0.1 0.0013 18.4 0.1 1.9 1 1 1 2 2 2 1 Kinetochore Sim4 complex subunit FTA2 Seadorna_VP7 PF07387.11 OQS05000.1 - 0.0037 16.4 0.1 0.0083 15.2 0.0 1.6 1 1 0 1 1 1 1 Seadornavirus VP7 Choline_kinase PF01633.20 OQS05000.1 - 0.0088 15.7 0.5 0.086 12.4 0.2 2.1 1 1 1 2 2 2 1 Choline/ethanolamine kinase LysM PF01476.20 OQS05001.1 - 3e-32 110.4 0.0 1.2e-08 34.8 0.0 4.3 4 0 0 4 4 4 4 LysM domain NAD_binding_7 PF13241.6 OQS05001.1 - 0.13 12.7 0.0 0.26 11.7 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding GTP_EFTU PF00009.27 OQS05002.1 - 4e-47 160.3 0.0 6e-47 159.7 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFTUD2 PF16004.5 OQS05002.1 - 1.4e-31 109.6 12.4 2.7e-31 108.7 12.4 1.4 1 0 0 1 1 1 1 116 kDa U5 small nuclear ribonucleoprotein component N-terminus EFG_C PF00679.24 OQS05002.1 - 2.9e-24 84.9 0.0 6.3e-23 80.6 0.0 2.4 2 0 0 2 2 2 1 Elongation factor G C-terminus EFG_IV PF03764.18 OQS05002.1 - 8.7e-24 83.6 0.0 1.7e-23 82.7 0.0 1.5 1 0 0 1 1 1 1 Elongation factor G, domain IV GTP_EFTU_D2 PF03144.25 OQS05002.1 - 1.3e-06 28.7 0.1 2.8e-06 27.6 0.1 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.6 OQS05002.1 - 7.9e-05 22.7 0.0 0.00019 21.4 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.23 OQS05002.1 - 0.00036 20.6 0.2 0.00075 19.6 0.2 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Roc PF08477.13 OQS05002.1 - 0.011 15.9 0.0 2.2 8.5 0.0 2.4 1 1 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 OQS05002.1 - 0.095 12.1 0.1 1.9 7.9 0.1 2.4 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit Ras PF00071.22 OQS05002.1 - 0.11 12.1 0.1 1.4 8.5 0.1 2.2 1 1 0 1 1 1 0 Ras family ECH_1 PF00378.20 OQS05003.1 - 1.4e-43 149.1 0.1 2.4e-43 148.3 0.1 1.3 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 OQS05003.1 - 1.3e-23 84.0 0.1 7e-21 75.1 0.0 2.0 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase Ion_trans PF00520.31 OQS05004.1 - 1.2e-28 100.0 17.4 1.9e-28 99.3 17.4 1.3 1 0 0 1 1 1 1 Ion transport protein cNMP_binding PF00027.29 OQS05004.1 - 1e-10 41.5 0.1 2.3e-10 40.4 0.1 1.5 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Ion_trans_2 PF07885.16 OQS05004.1 - 4.6e-10 39.3 7.0 4.6e-10 39.3 7.0 2.2 2 0 0 2 2 2 1 Ion channel TraE PF05309.11 OQS05004.1 - 0.15 11.4 2.2 0.23 10.8 0.4 2.1 2 0 0 2 2 2 0 TraE protein ELO PF01151.18 OQS05005.1 - 2e-51 174.9 30.1 2.3e-51 174.7 30.1 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family Pkinase PF00069.25 OQS05006.1 - 1.3e-211 700.0 0.0 2.6e-52 177.8 0.0 4.2 4 0 0 4 4 4 4 Protein kinase domain Pkinase_Tyr PF07714.17 OQS05006.1 - 6.8e-208 687.6 0.0 2e-53 181.3 0.0 4.2 4 0 0 4 4 4 4 Protein tyrosine kinase Pkinase_fungal PF17667.1 OQS05006.1 - 2.6e-12 46.2 0.2 0.086 11.6 0.0 4.2 4 0 0 4 4 4 4 Fungal protein kinase EphA2_TM PF14575.6 OQS05006.1 - 1.8e-09 38.3 0.0 0.52 11.2 0.0 4.5 4 0 0 4 4 4 3 Ephrin type-A receptor 2 transmembrane domain SKG6 PF08693.10 OQS05006.1 - 3.3e-09 36.0 24.6 0.0022 17.3 0.3 4.7 4 0 0 4 4 4 3 Transmembrane alpha-helix domain TMEM51 PF15345.6 OQS05006.1 - 3.9e-08 33.4 0.0 0.15 11.9 0.0 4.2 4 0 0 4 4 4 2 Transmembrane protein 51 Haspin_kinase PF12330.8 OQS05006.1 - 8.6e-08 31.5 0.7 1.1 8.1 0.0 4.5 4 0 0 4 4 4 3 Haspin like kinase domain Mid2 PF04478.12 OQS05006.1 - 5.5e-07 29.5 3.1 0.18 11.7 0.1 4.5 4 0 0 4 4 4 1 Mid2 like cell wall stress sensor Kdo PF06293.14 OQS05006.1 - 6e-07 29.0 3.6 0.99 8.7 0.1 4.3 4 0 0 4 4 4 2 Lipopolysaccharide kinase (Kdo/WaaP) family Amnionless PF14828.6 OQS05006.1 - 7.1e-07 28.4 0.0 0.39 9.5 0.0 3.4 3 0 0 3 3 3 3 Amnionless Adeno_E3_CR2 PF02439.15 OQS05006.1 - 1.3e-06 28.0 10.0 0.11 12.3 0.1 4.4 4 0 0 4 4 4 2 Adenovirus E3 region protein CR2 CD34_antigen PF06365.12 OQS05006.1 - 2.2e-06 27.4 0.1 0.38 10.3 0.0 4.6 4 0 0 4 4 4 1 CD34/Podocalyxin family TMEM154 PF15102.6 OQS05006.1 - 5.2e-06 26.4 0.0 0.076 12.9 0.0 4.0 3 0 0 3 3 3 1 TMEM154 protein family DUF4064 PF13273.6 OQS05006.1 - 6.2e-06 26.4 1.2 1.5 9.1 0.0 4.4 4 0 0 4 4 4 1 Protein of unknown function (DUF4064) Shisa PF13908.6 OQS05006.1 - 6.7e-06 26.5 0.6 0.021 15.1 0.2 3.9 4 0 0 4 4 4 1 Wnt and FGF inhibitory regulator DUF2207 PF09972.9 OQS05006.1 - 8.5e-06 24.8 0.0 2.5 6.8 0.0 3.9 4 0 0 4 4 4 1 Predicted membrane protein (DUF2207) VSP PF03302.13 OQS05006.1 - 9.7e-06 24.7 11.9 0.021 13.7 0.6 3.6 3 0 0 3 3 3 3 Giardia variant-specific surface protein APH PF01636.23 OQS05006.1 - 1.2e-05 25.3 0.2 9.4 6.1 0.0 4.8 4 0 0 4 4 4 0 Phosphotransferase enzyme family Podoplanin PF05808.11 OQS05006.1 - 2.2e-05 24.6 14.3 0.14 12.3 0.0 4.4 3 1 1 4 4 4 3 Podoplanin DUF4446 PF14584.6 OQS05006.1 - 4.6e-05 23.5 0.3 0.28 11.2 0.0 5.3 5 1 1 6 6 5 1 Protein of unknown function (DUF4446) DUF3147 PF11345.8 OQS05006.1 - 6e-05 23.4 2.9 1.6 9.1 0.0 3.8 3 0 0 3 3 3 1 Protein of unknown function (DUF3147) DUF4690 PF15756.5 OQS05006.1 - 0.00012 22.6 0.4 7.5 7.2 0.0 4.1 4 0 0 4 4 3 0 Small Novel Rich in Cartilage Herpes_gE PF02480.16 OQS05006.1 - 0.00015 20.7 0.0 0.36 9.5 0.0 3.0 3 0 0 3 3 3 1 Alphaherpesvirus glycoprotein E Pox_A14 PF05767.12 OQS05006.1 - 0.0004 20.5 0.2 0.58 10.4 0.0 3.5 3 0 0 3 3 3 1 Poxvirus virion envelope protein A14 Stevor PF17410.2 OQS05006.1 - 0.00058 19.5 0.8 7.8 5.9 0.0 4.1 4 0 0 4 4 3 0 Subtelomeric Variable Open Reading frame Protocadherin PF08374.11 OQS05006.1 - 0.0011 19.0 0.0 4.1 7.3 0.0 3.4 3 0 0 3 3 3 0 Protocadherin Yip1 PF04893.17 OQS05006.1 - 0.0024 17.6 1.7 14 5.3 0.1 3.8 4 0 0 4 4 4 0 Yip1 domain TerB_C PF15615.6 OQS05006.1 - 0.0034 17.7 1.5 97 3.2 0.0 4.9 5 0 0 5 5 5 0 TerB-C domain ECSCR PF15820.5 OQS05006.1 - 0.0049 16.7 0.1 6.3 6.7 0.0 4.0 4 0 0 4 4 4 0 Endothelial cell-specific chemotaxis regulator STE2 PF02116.15 OQS05006.1 - 0.0055 16.1 1.2 2.7 7.2 0.1 3.2 3 0 0 3 3 3 1 Fungal pheromone mating factor STE2 GPCR Colicin_V PF02674.16 OQS05006.1 - 0.0059 16.6 0.2 20 5.1 0.0 3.5 3 0 0 3 3 3 0 Colicin V production protein Insulin_TMD PF17870.1 OQS05006.1 - 0.0073 16.3 5.0 1.2 9.3 0.0 3.5 3 0 0 3 3 3 1 Insulin receptor trans-membrane segment Rax2 PF12768.7 OQS05006.1 - 0.012 15.1 0.0 4.7 6.6 0.0 4.2 5 0 0 5 5 4 0 Cortical protein marker for cell polarity Pneumo_M2 PF07380.11 OQS05006.1 - 0.014 15.7 3.6 21 5.5 0.1 4.4 4 0 0 4 4 4 0 Pneumovirus M2 protein PTP_tm PF18861.1 OQS05006.1 - 0.014 15.4 4.3 1.1 9.2 0.1 3.3 3 0 0 3 3 3 0 Transmembrane domain of protein tyrosine phosphatase, receptor type J DUF5305 PF17231.2 OQS05006.1 - 0.016 14.6 0.9 2.5 7.4 0.0 3.2 3 0 0 3 3 3 0 Family of unknown function (DUF5305) Orthoreo_P10 PF07204.11 OQS05006.1 - 0.019 14.9 0.3 1.1 9.2 0.0 3.4 4 0 0 4 4 3 0 Orthoreovirus membrane fusion protein p10 DUF3139 PF11337.8 OQS05006.1 - 0.02 15.5 0.0 2.5 8.8 0.0 3.8 4 0 0 4 4 3 0 Protein of unknown function (DUF3139) DUF347 PF03988.12 OQS05006.1 - 0.024 14.8 11.5 2.6 8.3 0.5 4.8 4 0 0 4 4 4 0 Repeat of Unknown Function (DUF347) DUF4834 PF16118.5 OQS05006.1 - 0.027 15.4 0.1 6.2 7.8 0.1 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4834) DUF5518 PF17647.1 OQS05006.1 - 0.034 14.3 8.9 8.4 6.6 0.2 3.7 4 0 0 4 4 3 0 Family of unknown function (DUF5518) H_PPase PF03030.16 OQS05006.1 - 0.04 12.6 0.6 5.2 5.6 0.0 3.0 3 0 0 3 3 3 0 Inorganic H+ pyrophosphatase DUF4121 PF13497.6 OQS05006.1 - 0.051 12.7 0.1 7.2 5.7 0.0 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4121) TMEM190 PF15431.6 OQS05006.1 - 0.066 13.4 0.2 28 4.9 0.0 3.4 3 0 0 3 3 2 0 Transmembrane protein 190 Oxidored_q3 PF00499.20 OQS05006.1 - 0.1 12.3 0.2 1.2e+02 2.4 0.0 3.7 4 0 0 4 4 4 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 CYYR1 PF10873.8 OQS05006.1 - 0.29 11.6 3.9 60 4.1 0.5 3.4 3 0 0 3 3 3 0 Cysteine and tyrosine-rich protein 1 DUF456 PF04306.13 OQS05006.1 - 0.5 10.7 8.8 19 5.5 0.6 3.9 3 0 0 3 3 3 0 Protein of unknown function (DUF456) Phage_holin_3_6 PF07332.11 OQS05006.1 - 0.71 9.9 7.0 22 5.1 0.1 3.9 4 0 0 4 4 3 0 Putative Actinobacterial Holin-X, holin superfamily III LapA_dom PF06305.11 OQS05006.1 - 4 7.3 12.4 11 5.9 0.2 4.3 4 0 0 4 4 4 0 Lipopolysaccharide assembly protein A domain Ank_2 PF12796.7 OQS05007.1 - 8.5e-29 100.0 0.0 1e-11 45.2 0.0 4.5 4 1 3 7 7 7 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQS05007.1 - 1.1e-18 67.4 2.6 8e-07 29.5 0.2 4.3 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 OQS05007.1 - 8e-16 57.9 0.3 6.6e-06 26.3 0.0 4.9 2 2 2 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQS05007.1 - 1.8e-14 52.4 0.5 0.0034 17.7 0.0 5.1 5 0 0 5 5 5 3 Ankyrin repeat Ank PF00023.30 OQS05007.1 - 1.3e-08 34.9 0.7 0.15 12.6 0.0 5.0 5 0 0 5 5 5 3 Ankyrin repeat FYVE PF01363.21 OQS05007.1 - 9.5e-05 22.5 14.7 0.00011 22.3 12.0 2.3 2 0 0 2 2 2 1 FYVE zinc finger DUF4208 PF13907.6 OQS05007.1 - 0.25 11.8 4.5 0.66 10.4 0.0 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4208) Cytochrom_C552 PF02335.15 OQS05007.1 - 0.43 9.4 10.8 0.031 13.2 2.0 3.0 3 0 0 3 3 3 0 Cytochrome c552 Cytochrom_CIII PF02085.16 OQS05007.1 - 2.8 8.3 12.0 1.1 9.6 8.9 1.9 2 0 0 2 2 2 0 Class III cytochrome C family hnRNP_Q_AcD PF18360.1 OQS05008.1 - 2.9e-12 46.4 0.1 5.4e-12 45.5 0.1 1.4 1 0 0 1 1 1 1 Heterogeneous nuclear ribonucleoprotein Q acidic domain RRM_1 PF00076.22 OQS05008.1 - 5.7e-12 45.3 0.3 2.7e-11 43.1 0.0 2.3 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DOT1 PF08123.13 OQS05009.1 - 1.2e-05 25.0 0.3 0.00029 20.4 0.3 2.0 1 1 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_25 PF13649.6 OQS05009.1 - 2.6e-05 24.9 0.1 4e-05 24.2 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 OQS05009.1 - 0.00017 21.0 0.0 0.00022 20.6 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_31 PF13847.6 OQS05009.1 - 0.0039 17.0 0.0 0.0049 16.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 OQS05009.1 - 0.017 14.6 0.0 0.023 14.2 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_23 PF13489.6 OQS05009.1 - 0.017 15.0 0.0 0.035 13.9 0.0 1.3 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_18 PF12847.7 OQS05009.1 - 0.076 12.9 0.0 0.1 12.5 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain PrmA PF06325.13 OQS05009.1 - 0.12 11.7 0.0 0.16 11.3 0.0 1.1 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Queuosine_synth PF02547.15 OQS05009.1 - 0.15 11.1 0.0 0.18 10.9 0.0 1.2 1 0 0 1 1 1 0 Queuosine biosynthesis protein PKD_channel PF08016.12 OQS05010.1 - 1.8e-51 175.2 9.9 1.8e-51 175.2 9.9 1.9 2 1 0 2 2 2 1 Polycystin cation channel Ion_trans PF00520.31 OQS05010.1 - 1.9e-06 27.3 16.4 1.9e-06 27.3 16.4 2.0 2 0 0 2 2 2 1 Ion transport protein Orthoreo_P10 PF07204.11 OQS05010.1 - 0.056 13.4 0.4 1.9 8.5 0.0 2.7 3 0 0 3 3 3 0 Orthoreovirus membrane fusion protein p10 DUF3985 PF13153.6 OQS05010.1 - 0.073 13.1 0.4 0.073 13.1 0.4 3.3 4 0 0 4 4 4 0 Protein of unknown function (DUF3985) TMCO5 PF14992.6 OQS05010.1 - 0.17 11.5 4.6 0.04 13.5 0.8 1.9 2 0 0 2 2 2 0 TMCO5 family SNAPc_SNAP43 PF09808.9 OQS05011.1 - 5.5e-14 52.5 1.6 7.9e-14 52.0 1.6 1.3 1 0 0 1 1 1 1 Small nuclear RNA activating complex (SNAPc), subunit SNAP43 Pkinase PF00069.25 OQS05013.1 - 2e-72 243.8 0.2 3.8e-72 242.8 0.2 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQS05013.1 - 2.2e-34 118.9 0.0 3.3e-34 118.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OQS05013.1 - 5.1e-05 22.2 0.0 7.6e-05 21.7 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 OQS05013.1 - 0.00058 19.3 0.0 0.0062 15.9 0.0 2.1 1 1 1 2 2 2 1 Kinase-like YrbL-PhoP_reg PF10707.9 OQS05013.1 - 0.019 14.5 0.0 0.035 13.6 0.0 1.4 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Kdo PF06293.14 OQS05013.1 - 0.023 14.0 0.3 0.033 13.5 0.3 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pox_ser-thr_kin PF05445.11 OQS05013.1 - 0.029 13.3 0.0 0.052 12.5 0.0 1.3 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase RIO1 PF01163.22 OQS05013.1 - 0.15 11.6 0.2 0.34 10.5 0.1 1.5 1 1 0 1 1 1 0 RIO1 family AnmK PF03702.14 OQS05013.1 - 0.16 11.0 0.0 0.57 9.2 0.0 1.8 2 0 0 2 2 2 0 Anhydro-N-acetylmuramic acid kinase Ribosomal_L14 PF00238.19 OQS05014.1 - 2.1e-33 115.0 0.0 2.5e-33 114.8 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e Ank_4 PF13637.6 OQS05015.1 - 3.2e-32 110.5 9.0 6.7e-11 42.5 0.1 4.7 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank_2 PF12796.7 OQS05015.1 - 6.4e-32 110.0 0.2 2.1e-15 57.1 0.1 2.7 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OQS05015.1 - 1.2e-25 86.7 3.5 1.6e-06 28.0 0.1 5.8 5 0 0 5 5 5 4 Ankyrin repeat Ank PF00023.30 OQS05015.1 - 3.5e-23 81.0 7.5 6.8e-05 23.1 0.1 6.0 6 0 0 6 6 6 4 Ankyrin repeat Ank_5 PF13857.6 OQS05015.1 - 2.2e-15 56.5 10.3 7.8e-06 26.1 0.2 3.8 1 1 3 4 4 4 4 Ankyrin repeats (many copies) DUF2808 PF10989.8 OQS05015.1 - 0.002 18.1 0.0 0.88 9.5 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF2808) BLACT_WH PF17778.1 OQS05015.1 - 0.022 14.7 0.1 31 4.7 0.0 3.7 3 0 0 3 3 3 0 Beta-lactamase associated winged helix domain Pkinase PF00069.25 OQS05016.1 - 6.8e-101 337.1 0.0 1.2e-53 182.1 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OQS05016.1 - 1.9e-98 328.9 0.0 1.2e-51 175.6 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Haspin_kinase PF12330.8 OQS05016.1 - 5.9e-06 25.5 0.1 0.035 13.0 0.0 2.8 2 1 0 2 2 2 2 Haspin like kinase domain Kdo PF06293.14 OQS05016.1 - 0.0045 16.4 0.1 0.49 9.7 0.0 2.4 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OQS05016.1 - 0.01 15.8 1.7 2.2 8.1 0.0 3.3 2 1 1 3 3 3 0 Phosphotransferase enzyme family DUF2207 PF09972.9 OQS05016.1 - 0.031 13.0 0.0 0.84 8.3 0.0 2.1 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) EphA2_TM PF14575.6 OQS05016.1 - 0.058 14.3 0.1 3.3 8.6 0.0 2.4 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Adeno_E3_CR2 PF02439.15 OQS05016.1 - 0.064 13.0 2.0 6 6.7 0.0 2.5 2 0 0 2 2 2 0 Adenovirus E3 region protein CR2 Pkinase_fungal PF17667.1 OQS05016.1 - 0.085 11.6 0.0 1 8.0 0.0 2.0 2 0 0 2 2 2 0 Fungal protein kinase Pox_EPC_I2-L1 PF12575.8 OQS05016.1 - 1.6 9.0 3.8 1.1 9.6 0.5 2.2 2 0 0 2 2 2 0 Poxvirus entry protein complex L1 and I2 SKG6 PF08693.10 OQS05016.1 - 3.3 7.2 6.3 7.2 6.1 2.2 2.7 2 0 0 2 2 2 0 Transmembrane alpha-helix domain Sigma_reg_N PF13800.6 OQS05016.1 - 3.3 8.1 4.6 1.2 9.5 0.2 2.5 4 0 0 4 4 2 0 Sigma factor regulator N-terminal CbtB PF09489.10 OQS05016.1 - 5.7 7.1 7.2 0.69 10.1 1.9 2.3 2 0 0 2 2 2 0 Probable cobalt transporter subunit (CbtB) Ribosomal_L4 PF00573.22 OQS05018.1 - 6.1e-39 133.7 1.2 1.5e-38 132.4 1.2 1.7 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Sec3_C PF09763.9 OQS05018.1 - 1.2e-35 123.1 31.8 8.2e-29 100.5 10.0 3.5 1 1 1 3 3 3 3 Exocyst complex component Sec3 Ribos_L4_asso_C PF14374.6 OQS05018.1 - 9.2e-27 92.9 1.1 9.2e-27 92.9 1.1 2.5 3 0 0 3 3 3 1 60S ribosomal protein L4 C-terminal domain Sec3-PIP2_bind PF15277.6 OQS05018.1 - 0.00052 20.1 0.2 0.0034 17.5 0.0 2.6 2 0 0 2 2 2 1 Exocyst complex component SEC3 N-terminal PIP2 binding PH WD40 PF00400.32 OQS05019.1 - 7e-05 23.5 15.1 0.37 11.8 0.2 5.8 6 1 1 7 7 7 3 WD domain, G-beta repeat ATG16 PF08614.11 OQS05019.1 - 0.012 15.8 6.1 0.021 15.1 6.1 1.3 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) CEP63 PF17045.5 OQS05019.1 - 0.016 15.1 4.8 0.025 14.5 4.8 1.2 1 0 0 1 1 1 0 Centrosomal protein of 63 kDa DUF724 PF05266.14 OQS05019.1 - 0.17 11.7 2.3 0.39 10.5 2.3 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF724) Mg_trans_NIPA PF05653.14 OQS05020.1 - 1.7e-32 112.8 13.2 1.4e-21 76.9 0.6 2.1 2 0 0 2 2 2 2 Magnesium transporter NIPA EamA PF00892.20 OQS05020.1 - 0.014 15.6 1.1 0.014 15.6 1.1 3.4 3 1 0 3 3 3 0 EamA-like transporter family DUF2583 PF10762.9 OQS05020.1 - 0.054 13.9 3.9 2.3 8.7 0.2 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2583) BRO1 PF03097.18 OQS05021.1 - 2.7e-18 66.0 0.2 1.3e-17 63.8 0.2 1.9 1 1 0 1 1 1 1 BRO1-like domain MFS_1 PF07690.16 OQS05022.1 - 7.3e-30 104.1 15.6 1.5e-15 57.0 6.7 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 OQS05022.1 - 0.044 12.6 5.0 0.009 14.9 1.7 1.7 2 0 0 2 2 2 0 MFS_1 like family MFS_3 PF05977.13 OQS05022.1 - 0.1 11.0 9.1 0.01 14.3 3.9 1.7 2 0 0 2 2 2 0 Transmembrane secretion effector Sec7 PF01369.20 OQS05023.1 - 3.2e-67 225.8 0.1 6.2e-67 224.8 0.1 1.5 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.7 OQS05023.1 - 1e-42 145.8 7.9 2e-42 144.8 4.9 3.0 2 0 0 2 2 2 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.10 OQS05023.1 - 1.8e-31 107.8 8.4 8.9e-29 99.2 0.2 5.3 5 0 0 5 5 5 2 Domain of unknown function (DUF1981) DCB PF16213.5 OQS05023.1 - 1.8e-20 73.3 1.6 1.8e-20 73.3 1.6 2.9 3 0 0 3 3 3 1 Dimerisation and cyclophilin-binding domain of Mon2 GlcNAc PF11397.8 OQS05024.1 - 2.9e-45 155.3 0.0 2.7e-37 129.0 0.1 2.1 1 1 1 2 2 2 2 Glycosyltransferase (GlcNAc) Kinesin PF00225.23 OQS05026.1 - 1e-95 320.5 0.3 2.1e-95 319.5 0.3 1.5 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 OQS05026.1 - 3.4e-47 160.1 0.1 3.4e-47 160.1 0.1 2.6 3 0 0 3 3 3 1 Microtubule binding Torsin PF06309.11 OQS05026.1 - 0.049 13.7 0.0 0.16 12.1 0.0 1.8 1 0 0 1 1 1 0 Torsin Med11 PF10280.9 OQS05026.1 - 0.066 13.7 5.8 0.051 14.0 1.9 2.8 2 1 0 2 2 2 0 Mediator complex protein Arb2 PF09757.9 OQS05027.1 - 0.0026 17.0 0.0 0.0034 16.6 0.0 1.1 1 0 0 1 1 1 1 Arb2 domain MlaA PF04333.13 OQS05028.1 - 0.04 13.6 0.0 0.073 12.8 0.0 1.7 1 0 0 1 1 1 0 MlaA lipoprotein Glyco_hydro_72 PF03198.14 OQS05029.1 - 5.9e-31 107.9 0.2 2.2e-10 40.3 0.0 3.1 3 0 0 3 3 3 3 Glucanosyltransferase ACBP PF00887.19 OQS05030.1 - 1.3e-27 95.8 0.2 2.2e-27 95.1 0.2 1.4 1 0 0 1 1 1 1 Acyl CoA binding protein Ank_2 PF12796.7 OQS05030.1 - 2.1e-20 73.1 1.1 6.4e-15 55.5 0.2 2.5 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQS05030.1 - 5.6e-18 65.1 0.4 5.2e-10 39.6 0.0 3.7 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 OQS05030.1 - 2e-15 56.6 0.2 6.7e-11 42.2 0.1 2.9 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 OQS05030.1 - 1.6e-14 53.6 1.1 1.3e-05 25.4 0.0 4.4 4 0 0 4 4 4 2 Ankyrin repeat Ank_3 PF13606.6 OQS05030.1 - 2.1e-12 46.0 0.2 2.9e-05 24.1 0.1 3.6 4 0 0 4 4 4 2 Ankyrin repeat adh_short PF00106.25 OQS05031.1 - 1.2e-17 64.1 1.7 3.1e-17 62.7 1.7 1.7 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OQS05031.1 - 3.4e-10 39.9 1.3 1.3e-09 38.0 1.3 1.9 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Ham1p_like PF01725.16 OQS05031.1 - 0.078 12.9 0.0 0.16 11.9 0.0 1.5 2 0 0 2 2 2 0 Ham1 family SDF PF00375.18 OQS05032.1 - 8.4e-69 232.5 47.9 3.3e-68 230.5 47.9 1.7 1 1 0 1 1 1 1 Sodium:dicarboxylate symporter family Aa_trans PF01490.18 OQS05033.1 - 5.1e-69 233.0 65.2 1.4e-35 122.8 27.4 2.3 2 0 0 2 2 2 2 Transmembrane amino acid transporter protein Cellulase PF00150.18 OQS05033.1 - 2.6e-08 33.6 0.7 6.1e-08 32.4 0.7 1.5 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Astacin PF01400.24 OQS05034.1 - 1.1e-15 57.8 5.2 6.1e-14 52.1 7.1 2.7 2 1 0 2 2 2 1 Astacin (Peptidase family M12A) Nramp PF01566.18 OQS05035.1 - 1.1e-75 254.9 15.2 1.7e-75 254.2 15.2 1.3 1 0 0 1 1 1 1 Natural resistance-associated macrophage protein IP_trans PF02121.18 OQS05035.1 - 2e-74 250.3 0.0 2.9e-74 249.8 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylinositol transfer protein zf-RING_UBOX PF13445.6 OQS05036.1 - 5.6e-08 32.7 7.5 1.1e-07 31.7 2.6 2.4 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_2 PF13639.6 OQS05036.1 - 5.7e-08 33.0 6.7 1.1e-07 32.0 6.7 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 OQS05036.1 - 2.4e-06 27.3 4.9 4.5e-06 26.4 4.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 OQS05036.1 - 5.8e-05 22.9 5.5 0.00012 21.8 5.5 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 OQS05036.1 - 7.3e-05 22.8 6.7 0.00065 19.8 7.1 2.1 1 1 1 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 OQS05036.1 - 0.00024 21.0 5.7 0.00039 20.3 5.7 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-Nse PF11789.8 OQS05036.1 - 0.001 18.9 1.3 0.0021 17.9 1.3 1.4 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4_2 PF13923.6 OQS05036.1 - 0.0011 18.8 7.1 0.002 17.9 7.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 OQS05036.1 - 0.0014 18.3 3.7 0.0014 18.3 3.7 2.4 2 0 0 2 2 2 1 RING-like zinc finger Prok-RING_4 PF14447.6 OQS05036.1 - 0.0064 16.3 7.4 0.012 15.5 7.4 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_6 PF14835.6 OQS05036.1 - 0.052 13.4 4.5 0.099 12.5 4.5 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-rbx1 PF12678.7 OQS05036.1 - 2.1 8.7 9.3 5.8 7.3 7.0 2.7 2 1 0 2 2 2 0 RING-H2 zinc finger domain Aa_trans PF01490.18 OQS05038.1 - 3.7e-39 134.6 22.8 5e-39 134.2 22.8 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein FANCI_S4 PF14678.6 OQS05039.1 - 6.5e-24 84.4 3.1 9.2e-23 80.6 3.1 2.7 1 1 0 1 1 1 1 FANCI solenoid 4 FANCI_S2 PF14676.6 OQS05039.1 - 2.7e-22 79.8 0.5 2.7e-22 79.8 0.5 3.6 2 2 0 2 2 2 1 FANCI solenoid 2 FANCI_S1 PF14675.6 OQS05039.1 - 1e-11 44.8 0.9 1e-11 44.8 0.9 3.5 4 0 0 4 4 4 1 FANCI solenoid 1 FANCI_HD2 PF14680.6 OQS05039.1 - 1.4e-05 24.4 3.6 0.00075 18.8 0.0 4.1 4 0 0 4 4 4 2 FANCI helical domain 2 SPATIAL PF15256.6 OQS05040.1 - 0.0024 18.2 0.5 0.0027 18.1 0.5 1.1 1 0 0 1 1 1 1 SPATIAL TruD PF01142.18 OQS05040.1 - 0.037 12.8 0.8 0.052 12.4 0.6 1.3 1 1 0 1 1 1 0 tRNA pseudouridine synthase D (TruD) LPD5 PF18799.1 OQS05040.1 - 0.1 13.0 1.2 0.67 10.4 1.0 1.8 1 1 1 2 2 2 0 Large polyvalent protein-associated domain 5 FapA PF03961.13 OQS05040.1 - 3 6.4 6.1 3.4 6.2 6.1 1.0 1 0 0 1 1 1 0 Flagellar Assembly Protein A MTS PF05175.14 OQS05041.1 - 2.9e-11 43.2 0.0 7.6e-10 38.6 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase small domain PrmA PF06325.13 OQS05041.1 - 5e-06 26.1 0.2 0.00033 20.1 0.1 2.0 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.6 OQS05041.1 - 9.7e-05 23.0 0.0 0.00018 22.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.9 OQS05041.1 - 0.00026 20.8 0.0 0.00039 20.2 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase UPF0020 PF01170.18 OQS05041.1 - 0.0017 18.0 0.5 0.006 16.3 0.0 2.0 2 1 0 2 2 2 1 Putative RNA methylase family UPF0020 Methyltransf_31 PF13847.6 OQS05041.1 - 0.017 14.9 0.0 0.02 14.7 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Cons_hypoth95 PF03602.15 OQS05041.1 - 0.032 13.9 0.0 0.053 13.2 0.0 1.4 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Hid1 PF12722.7 OQS05042.1 - 7e-194 646.3 6.6 1.1e-163 546.4 5.6 2.0 1 1 1 2 2 2 2 High-temperature-induced dauer-formation protein Dymeclin PF09742.9 OQS05042.1 - 7.9e-184 612.6 2.1 8.9e-184 612.4 2.1 1.0 1 0 0 1 1 1 1 Dyggve-Melchior-Clausen syndrome protein Ku_PK_bind PF08785.11 OQS05042.1 - 0.11 12.7 0.1 0.85 9.8 0.0 2.4 2 0 0 2 2 2 0 Ku C terminal domain like Peptidase_C26 PF07722.13 OQS05043.1 - 1e-21 77.7 0.0 1.2e-20 74.2 0.0 2.2 1 1 0 1 1 1 1 Peptidase C26 GATase PF00117.28 OQS05043.1 - 1.5e-10 41.1 0.0 2.5e-10 40.5 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase class-I SDF PF00375.18 OQS05044.1 - 1.1e-70 238.7 33.7 4.8e-70 236.6 33.7 1.8 1 1 0 1 1 1 1 Sodium:dicarboxylate symporter family SPC12 PF06645.13 OQS05044.1 - 1.3 9.1 5.8 0.93 9.6 0.7 3.2 3 0 0 3 3 3 0 Microsomal signal peptidase 12 kDa subunit (SPC12) PDEase_I PF00233.19 OQS05045.1 - 1e-72 244.7 0.0 3e-72 243.2 0.0 1.9 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase FYVE PF01363.21 OQS05045.1 - 5e-11 42.6 14.1 2.1e-10 40.6 14.1 2.2 1 0 0 1 1 1 1 FYVE zinc finger START PF01852.19 OQS05045.1 - 8.8e-08 31.8 0.1 1.8e-07 30.8 0.1 1.4 1 0 0 1 1 1 1 START domain FYVE_2 PF02318.16 OQS05045.1 - 0.0037 17.5 6.9 0.016 15.5 6.9 2.1 1 0 0 1 1 1 1 FYVE-type zinc finger Malate_DH PF12434.8 OQS05045.1 - 1.8 8.7 3.9 7.1 6.8 0.0 2.8 2 0 0 2 2 2 0 Malate dehydrogenase enzyme Astacin PF01400.24 OQS05046.1 - 9.7e-16 57.9 4.0 7.3e-15 55.1 4.0 2.1 1 1 0 1 1 1 1 Astacin (Peptidase family M12A) Exo_endo_phos PF03372.23 OQS05047.1 - 7.4e-14 51.8 0.1 1.1e-13 51.2 0.1 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family RhoGAP PF00620.27 OQS05047.1 - 2.2e-13 50.3 0.1 7.1e-12 45.4 0.1 2.5 1 1 0 1 1 1 1 RhoGAP domain RsbRD_N PF14361.6 OQS05048.1 - 0.091 13.5 0.1 0.22 12.2 0.0 1.6 2 0 0 2 2 2 0 RsbT co-antagonist protein rsbRD N-terminal domain SWIM PF04434.17 OQS05050.1 - 0.00024 20.7 0.0 0.00037 20.1 0.0 1.3 1 0 0 1 1 1 1 SWIM zinc finger Lipoprot_C PF08794.10 OQS05050.1 - 0.057 13.4 0.0 0.09 12.8 0.0 1.2 1 0 0 1 1 1 0 Lipoprotein GNA1870 C terminal like PX PF00787.24 OQS05051.1 - 8.9e-07 28.9 5.1 0.016 15.2 0.0 4.7 3 2 0 3 3 3 2 PX domain DUF5338 PF17273.2 OQS05051.1 - 3.8e-05 23.7 0.0 0.5 10.5 0.0 3.7 3 0 0 3 3 3 1 Family of unknown function (DUF5338) Xpo1 PF08389.12 OQS05051.1 - 0.022 14.8 2.9 8.7 6.4 0.0 3.2 3 0 0 3 3 3 0 Exportin 1-like protein DUF4240 PF14024.6 OQS05051.1 - 0.067 13.4 1.4 23 5.2 0.1 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF4240) GPR_Gpa2_C PF11970.8 OQS05051.1 - 0.092 12.8 0.0 83 3.4 0.0 3.3 3 0 0 3 3 3 0 G protein-coupled glucose receptor regulating Gpa2 C-term Complex1_49kDa PF00346.19 OQS05051.1 - 0.16 11.0 0.3 2.1 7.4 0.0 2.1 2 0 0 2 2 2 0 Respiratory-chain NADH dehydrogenase, 49 Kd subunit HbrB PF08539.11 OQS05051.1 - 0.2 11.6 3.6 1.9 8.5 0.1 3.1 3 0 0 3 3 3 0 HbrB-like Usg PF06233.12 OQS05051.1 - 1.9 8.7 5.0 10 6.4 0.1 3.4 3 1 0 3 3 3 0 Usg-like family WD40 PF00400.32 OQS05053.1 - 2e-52 174.0 25.7 3.4e-08 34.0 0.1 8.1 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OQS05053.1 - 1.2e-13 51.1 0.1 0.0041 17.4 0.0 5.0 1 1 2 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain MORN PF02493.20 OQS05054.1 - 2.2e-25 87.0 33.2 6e-06 25.9 0.2 8.9 9 0 0 9 9 9 6 MORN repeat IQ PF00612.27 OQS05054.1 - 2.8e-11 42.2 54.4 0.0058 16.3 1.2 8.3 7 0 0 7 7 7 6 IQ calmodulin-binding motif WW PF00397.26 OQS05054.1 - 8.4e-11 41.8 22.8 5.7e-07 29.5 4.2 3.6 3 0 0 3 3 3 2 WW domain fn3 PF00041.21 OQS05054.1 - 3.5e-05 24.1 0.0 0.00071 19.9 0.0 2.8 2 0 0 2 2 2 1 Fibronectin type III domain LRR_4 PF12799.7 OQS05054.1 - 0.014 15.8 16.7 8.3 7.0 0.7 7.8 6 2 4 10 10 10 0 Leucine Rich repeats (2 copies) zf-C2H2_jaz PF12171.8 OQS05054.1 - 0.49 10.8 6.2 0.7 10.3 1.1 2.8 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding PARP PF00644.20 OQS05056.1 - 7.6e-36 123.5 0.0 1.6e-35 122.5 0.0 1.5 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain PARP_reg PF02877.14 OQS05056.1 - 5.4e-35 120.5 0.3 1.8e-34 118.7 0.3 2.0 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase, regulatory domain WGR PF05406.15 OQS05056.1 - 1.3e-19 70.1 0.7 3.5e-19 68.7 0.7 1.8 1 0 0 1 1 1 1 WGR domain FYVE PF01363.21 OQS05057.1 - 1.3e-05 25.3 11.0 2.9e-05 24.1 11.0 1.6 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.16 OQS05057.1 - 0.0014 18.8 5.0 0.0014 18.8 5.0 1.8 2 0 0 2 2 2 1 FYVE-type zinc finger DUF3074 PF11274.8 OQS05057.1 - 0.028 14.4 0.4 0.24 11.4 0.0 2.3 2 2 0 2 2 2 0 Protein of unknown function (DUF3074) BspA_v PF18220.1 OQS05057.1 - 0.085 13.0 0.6 0.4 10.8 0.0 2.3 3 0 0 3 3 3 0 Adhesin BspA variable domain NOB1_Zn_bind PF08772.11 OQS05057.1 - 5.2 7.3 15.0 2.9 8.1 8.3 2.7 1 1 1 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like zf-B_box PF00643.24 OQS05057.1 - 5.6 7.2 10.0 6.8 6.9 5.7 2.3 2 0 0 2 2 2 0 B-box zinc finger NAP PF00956.18 OQS05058.1 - 6.5e-76 255.1 4.7 2.4e-75 253.2 3.8 2.3 2 0 0 2 2 2 1 Nucleosome assembly protein (NAP) UCH PF00443.29 OQS05058.1 - 4.5e-22 78.8 0.0 8.7e-22 77.8 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 OQS05058.1 - 0.00011 21.9 0.0 0.00023 20.9 0.0 1.5 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UBA PF00627.31 OQS05058.1 - 0.0024 17.8 0.0 0.0061 16.4 0.0 1.7 1 0 0 1 1 1 1 UBA/TS-N domain Sporozoite_P67 PF05642.11 OQS05058.1 - 0.013 13.7 5.1 0.018 13.1 5.1 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Cwf_Cwc_15 PF04889.12 OQS05058.1 - 0.021 14.6 5.4 0.044 13.5 5.4 1.5 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein PBP1_TM PF14812.6 OQS05058.1 - 0.18 12.2 17.1 0.64 10.4 17.1 1.9 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal RNA_pol_3_Rpc31 PF11705.8 OQS05058.1 - 0.97 9.6 14.4 0.095 12.9 8.6 2.1 3 0 0 3 3 3 0 DNA-directed RNA polymerase III subunit Rpc31 DUF2457 PF10446.9 OQS05058.1 - 4.2 6.4 15.6 6.9 5.7 15.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) PTPRCAP PF15713.5 OQS05058.1 - 4.9 7.4 10.3 0.61 10.4 5.7 1.8 2 0 0 2 2 2 0 Protein tyrosine phosphatase receptor type C-associated YL1 PF05764.13 OQS05058.1 - 5 7.2 10.7 12 5.9 10.7 1.6 1 0 0 1 1 1 0 YL1 nuclear protein NOA36 PF06524.12 OQS05058.1 - 6.6 6.0 14.6 11 5.2 14.6 1.3 1 0 0 1 1 1 0 NOA36 protein XPA_C PF05181.12 OQS05059.1 - 1e-13 51.0 1.1 1.9e-13 50.1 1.1 1.4 1 0 0 1 1 1 1 XPA protein C-terminus CENP-K PF11802.8 OQS05059.1 - 0.02 14.4 3.2 0.024 14.2 3.2 1.1 1 0 0 1 1 1 0 Centromere-associated protein K DUF2046 PF09755.9 OQS05060.1 - 1.6e-28 99.8 35.4 2.1e-28 99.4 35.4 1.0 1 0 0 1 1 1 1 Uncharacterized conserved protein H4 (DUF2046) CVNH PF08881.10 OQS05060.1 - 0.29 11.8 2.0 0.77 10.5 0.7 2.2 1 1 1 2 2 2 0 CVNH domain Gti1_Pac2 PF09729.9 OQS05060.1 - 0.39 10.8 3.3 0.65 10.1 3.3 1.5 1 0 0 1 1 1 0 Gti1/Pac2 family Rootletin PF15035.6 OQS05060.1 - 1.6 8.7 30.9 0.87 9.6 8.6 3.2 1 1 2 3 3 3 0 Ciliary rootlet component, centrosome cohesion AAA_11 PF13086.6 OQS05060.1 - 8.9 6.0 18.8 14 5.3 18.2 1.7 1 1 0 1 1 1 0 AAA domain MutL_C PF08676.11 OQS05061.1 - 1.5e-16 60.5 0.0 2.7e-16 59.7 0.0 1.4 1 0 0 1 1 1 1 MutL C terminal dimerisation domain HATPase_c_3 PF13589.6 OQS05061.1 - 1.2e-06 28.4 0.2 3.8e-06 26.8 0.2 1.9 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 OQS05061.1 - 0.00092 19.7 0.0 0.0019 18.7 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase TMF_TATA_bd PF12325.8 OQS05062.1 - 5.1e-15 55.7 18.9 5.1e-15 55.7 18.9 7.1 1 1 2 6 6 6 1 TATA element modulatory factor 1 TATA binding TMF_DNA_bd PF12329.8 OQS05062.1 - 4.7e-08 32.9 7.4 4.7e-08 32.9 7.4 8.9 6 3 3 9 9 9 1 TATA element modulatory factor 1 DNA binding Homeodomain PF00046.29 OQS05062.1 - 0.49 10.3 5.4 0.31 10.9 0.7 3.1 2 0 0 2 2 2 0 Homeodomain EF-hand_8 PF13833.6 OQS05063.1 - 1e-06 28.5 0.6 2.2e-06 27.4 0.6 1.6 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 OQS05063.1 - 0.00011 21.5 1.3 0.0035 16.8 1.3 2.4 2 0 0 2 2 2 1 EF hand EF-hand_7 PF13499.6 OQS05063.1 - 0.00019 21.8 0.2 0.0044 17.4 0.1 2.5 2 0 0 2 2 2 1 EF-hand domain pair DUF512 PF04459.12 OQS05063.1 - 0.043 13.1 0.0 0.059 12.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF512) Myb_DNA-binding PF00249.31 OQS05064.1 - 2.9e-11 43.4 0.9 4.1e-11 42.9 0.2 1.6 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OQS05064.1 - 0.0061 16.8 0.1 0.0095 16.2 0.1 1.4 1 1 0 1 1 1 1 Myb-like DNA-binding domain DnaJ_C PF01556.18 OQS05065.1 - 4.9e-41 140.3 0.1 7.3e-41 139.7 0.1 1.3 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 OQS05065.1 - 1.1e-28 99.1 2.9 1.9e-28 98.4 2.9 1.4 1 0 0 1 1 1 1 DnaJ domain RPT PF13446.6 OQS05065.1 - 0.13 12.2 0.0 0.52 10.3 0.0 2.0 2 1 0 2 2 2 0 A repeated domain in UCH-protein Complex1_LYR PF05347.15 OQS05066.1 - 3.2e-15 55.9 0.1 4.3e-15 55.5 0.1 1.2 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 OQS05066.1 - 9.1e-07 29.5 0.4 1.1e-06 29.3 0.4 1.1 1 0 0 1 1 1 1 Complex1_LYR-like DZR PF12773.7 OQS05066.1 - 5.6e-05 23.1 0.2 5.6e-05 23.1 0.2 1.6 2 0 0 2 2 2 1 Double zinc ribbon NOB1_Zn_bind PF08772.11 OQS05066.1 - 0.00042 20.4 0.6 0.0012 18.9 0.2 2.0 2 1 1 3 3 3 1 Nin one binding (NOB1) Zn-ribbon like zf-ribbon_3 PF13248.6 OQS05066.1 - 0.00049 19.4 2.3 0.00049 19.4 2.3 1.8 2 0 0 2 2 2 1 zinc-ribbon domain zinc_ribbon_2 PF13240.6 OQS05066.1 - 0.0068 16.1 3.5 0.015 15.0 3.5 1.6 1 0 0 1 1 1 1 zinc-ribbon domain Complex1_LYR_1 PF13232.6 OQS05066.1 - 0.031 14.9 0.1 0.042 14.4 0.1 1.2 1 0 0 1 1 1 0 Complex1_LYR-like zinc_ribbon_15 PF17032.5 OQS05066.1 - 0.041 14.6 3.2 0.052 14.3 3.2 1.5 1 1 0 1 1 1 0 zinc-ribbon family HypA PF01155.19 OQS05066.1 - 0.1 12.7 1.1 0.097 12.7 0.7 1.4 1 1 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA PLATZ PF04640.14 OQS05066.1 - 0.1 13.2 1.3 0.13 12.9 1.3 1.4 1 1 0 1 1 1 0 PLATZ transcription factor ADK_lid PF05191.14 OQS05066.1 - 0.14 12.2 0.7 0.38 10.8 0.7 1.8 1 0 0 1 1 1 0 Adenylate kinase, active site lid zf-NADH-PPase PF09297.11 OQS05066.1 - 0.21 11.3 4.2 1.6 8.5 0.6 2.5 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain Integrase_Zn PF02022.19 OQS05066.1 - 0.23 11.5 0.0 0.23 11.5 0.0 2.3 3 0 0 3 3 3 0 Integrase Zinc binding domain Cript PF10235.9 OQS05066.1 - 0.76 10.4 5.1 0.24 12.0 2.2 1.7 1 1 1 2 2 2 0 Microtubule-associated protein CRIPT DHC_N1 PF08385.12 OQS05067.1 - 1e-183 612.1 17.0 1e-183 612.1 17.0 3.4 4 1 0 4 4 4 1 Dynein heavy chain, N-terminal region 1 AAA_6 PF12774.7 OQS05067.1 - 7.7e-145 481.9 0.3 1.3e-142 474.6 0.0 3.3 4 0 0 4 4 4 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 OQS05067.1 - 4.9e-109 365.1 6.4 4.9e-109 365.1 6.4 4.1 6 0 0 6 6 5 1 Dynein heavy chain, N-terminal region 2 AAA_8 PF12780.7 OQS05067.1 - 5.3e-87 291.4 0.0 2.6e-86 289.1 0.0 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region D4 Dynein_C PF18199.1 OQS05067.1 - 1.1e-85 287.5 0.8 4.3e-85 285.6 0.0 2.4 3 0 0 3 3 2 1 Dynein heavy chain C-terminal domain AAA_9 PF12781.7 OQS05067.1 - 1.3e-73 246.8 1.4 1.8e-72 243.0 1.1 3.0 2 0 0 2 2 2 1 ATP-binding dynein motor region AAA_7 PF12775.7 OQS05067.1 - 5.9e-54 182.3 1.6 2.9e-48 163.8 0.0 4.6 4 0 0 4 4 4 2 P-loop containing dynein motor region AAA_lid_11 PF18198.1 OQS05067.1 - 4.3e-51 173.0 0.0 9.6e-51 171.8 0.0 1.7 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 OQS05067.1 - 2.8e-41 140.3 0.0 2.5e-40 137.3 0.0 2.9 2 0 0 2 2 1 1 Dynein heavy chain region D6 P-loop domain MT PF12777.7 OQS05067.1 - 2.1e-40 138.8 12.7 2.1e-40 138.8 12.7 2.7 3 0 0 3 3 3 1 Microtubule-binding stalk of dynein motor AAA_5 PF07728.14 OQS05067.1 - 2.2e-17 63.4 2.3 4.9e-07 29.8 0.0 7.7 7 1 0 7 7 7 4 AAA domain (dynein-related subfamily) Dynein_AAA_lid PF17852.1 OQS05067.1 - 3.2e-17 62.8 0.1 2.5e-16 59.9 0.1 2.8 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_lid_1 PF17857.1 OQS05067.1 - 2.2e-15 56.7 0.1 1.3e-14 54.2 0.1 2.4 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 OQS05067.1 - 1.2e-09 38.8 0.0 0.26 11.7 0.0 5.7 4 0 0 4 4 4 3 AAA ATPase domain AAA PF00004.29 OQS05067.1 - 1.7e-08 34.9 0.6 0.67 10.4 0.0 5.6 5 0 0 5 5 5 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 OQS05067.1 - 3.3e-07 30.7 5.9 0.63 10.3 0.0 5.7 6 0 0 6 6 5 2 AAA domain AAA_18 PF13238.6 OQS05067.1 - 0.00017 22.1 0.2 3.7 8.1 0.0 4.5 4 0 0 4 4 3 2 AAA domain RNA_helicase PF00910.22 OQS05067.1 - 0.00019 21.8 0.1 0.087 13.2 0.0 3.9 3 0 0 3 3 3 1 RNA helicase AAA_30 PF13604.6 OQS05067.1 - 0.00055 19.7 2.3 0.54 10.0 0.0 3.8 3 0 0 3 3 3 1 AAA domain AAA_33 PF13671.6 OQS05067.1 - 0.0014 18.8 0.3 16 5.6 0.0 4.4 4 0 0 4 4 4 0 AAA domain ABC_tran PF00005.27 OQS05067.1 - 0.018 15.5 2.2 60 4.2 0.0 4.6 5 0 0 5 5 3 0 ABC transporter Sigma54_activat PF00158.26 OQS05067.1 - 0.025 14.3 0.0 3.3 7.4 0.0 3.4 3 0 0 3 3 3 0 Sigma-54 interaction domain Mg_chelatase PF01078.21 OQS05067.1 - 0.028 13.8 0.3 3.2 7.1 0.0 3.5 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI AAA_28 PF13521.6 OQS05067.1 - 0.031 14.5 0.1 15 5.8 0.1 4.0 3 0 0 3 3 3 0 AAA domain AAA_19 PF13245.6 OQS05067.1 - 0.081 13.3 6.3 16 5.9 0.0 4.3 4 0 0 4 4 3 0 AAA domain AAA_24 PF13479.6 OQS05067.1 - 7.1 6.3 7.1 40 3.8 0.1 4.3 4 0 0 4 4 4 0 AAA domain Pkinase_Tyr PF07714.17 OQS05068.1 - 6.1e-56 189.6 0.0 7.5e-56 189.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OQS05068.1 - 4.3e-54 183.7 0.0 5.5e-54 183.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 OQS05068.1 - 0.0011 18.4 0.0 0.0037 16.6 0.0 1.8 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 OQS05068.1 - 0.002 17.0 0.0 0.0036 16.1 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase DUF676 PF05057.14 OQS05070.1 - 0.15 11.6 0.0 0.25 10.8 0.0 1.3 1 0 0 1 1 1 0 Putative serine esterase (DUF676) WD40 PF00400.32 OQS05071.1 - 2.1e-26 91.6 6.0 3.6e-06 27.6 0.1 4.9 4 0 0 4 4 4 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OQS05071.1 - 2.2e-11 43.9 0.1 0.0085 16.4 0.0 5.0 5 2 0 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 OQS05071.1 - 0.11 11.2 0.1 5.6 5.5 0.0 2.6 2 1 1 3 3 3 0 Nucleoporin Nup120/160 BBS2_Mid PF14783.6 OQS05071.1 - 0.11 12.6 0.0 86 3.2 0.0 4.1 5 0 0 5 5 5 0 Ciliary BBSome complex subunit 2, middle region PI3_PI4_kinase PF00454.27 OQS05072.1 - 6.3e-46 157.2 0.0 1.4e-45 156.1 0.0 1.7 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase SMG1 PF15785.5 OQS05072.1 - 4.2e-18 65.1 14.0 1e-14 53.9 1.2 3.3 2 1 1 3 3 3 2 Serine/threonine-protein kinase smg-1 FATC PF02260.20 OQS05072.1 - 1e-12 47.6 0.5 3.4e-12 45.9 0.5 2.0 1 0 0 1 1 1 1 FATC domain FRB_dom PF08771.11 OQS05072.1 - 0.024 15.1 3.8 3.1 8.3 0.0 4.1 2 1 0 3 3 3 0 FKBP12-rapamycin binding domain HEAT PF02985.22 OQS05072.1 - 0.096 13.0 0.4 8.3 7.0 0.1 3.3 2 0 0 2 2 2 0 HEAT repeat CUE PF02845.16 OQS05073.1 - 2e-11 43.4 2.9 0.0027 17.4 0.0 3.6 3 0 0 3 3 3 3 CUE domain Smr PF01713.21 OQS05073.1 - 9.1e-09 35.6 0.0 2.6e-08 34.1 0.0 1.8 1 0 0 1 1 1 1 Smr domain Sigma70_r1_1 PF03979.14 OQS05073.1 - 0.025 14.6 3.0 2.8 8.1 0.1 2.6 2 0 0 2 2 2 0 Sigma-70 factor, region 1.1 DUF2489 PF10675.9 OQS05073.1 - 0.028 14.3 0.5 0.15 12.0 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2489) DUF2420 PF10336.9 OQS05073.1 - 0.14 12.2 5.2 0.4 10.7 0.1 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2420) 3HCDH_N PF02737.18 OQS05074.1 - 3.9e-38 131.1 0.0 5.2e-38 130.7 0.0 1.1 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_2 PF03446.15 OQS05074.1 - 3.3e-06 27.4 0.0 6.7e-06 26.4 0.0 1.5 1 1 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase ApbA PF02558.16 OQS05074.1 - 0.00022 20.9 0.1 0.00047 19.8 0.1 1.6 1 1 0 1 1 1 1 Ketopantoate reductase PanE/ApbA 2-Hacid_dh_C PF02826.19 OQS05074.1 - 0.0022 17.4 0.0 0.0038 16.6 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain SMK-1 PF04802.15 OQS05074.1 - 0.0033 17.3 0.0 0.0045 16.8 0.0 1.1 1 0 0 1 1 1 1 Component of IIS longevity pathway SMK-1 NAD_Gly3P_dh_N PF01210.23 OQS05074.1 - 0.0034 17.4 0.0 0.0057 16.7 0.0 1.5 1 1 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus DAO PF01266.24 OQS05074.1 - 0.0036 16.9 0.0 0.0045 16.6 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase TrkA_N PF02254.18 OQS05074.1 - 0.021 15.1 0.0 0.056 13.7 0.0 1.7 1 0 0 1 1 1 0 TrkA-N domain F420_oxidored PF03807.17 OQS05074.1 - 0.024 15.2 0.0 0.11 13.1 0.0 2.0 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent NAD_binding_8 PF13450.6 OQS05074.1 - 0.038 14.2 0.0 0.076 13.3 0.0 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain UDPG_MGDP_dh_N PF03721.14 OQS05074.1 - 0.048 13.2 0.0 0.079 12.5 0.0 1.5 1 1 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain ThiF PF00899.21 OQS05074.1 - 0.058 12.7 0.2 0.65 9.3 0.6 2.0 1 1 0 2 2 2 0 ThiF family GIDA PF01134.22 OQS05074.1 - 0.092 11.8 0.1 0.34 9.9 0.0 1.8 2 0 0 2 2 2 0 Glucose inhibited division protein A Sacchrp_dh_NADP PF03435.18 OQS05074.1 - 0.11 12.7 0.0 0.2 11.9 0.0 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Ank_2 PF12796.7 OQS05075.1 - 2.4e-137 447.8 54.3 7.7e-21 74.5 0.1 11.7 2 2 10 12 12 12 12 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQS05075.1 - 2.1e-115 375.8 29.0 6.4e-14 52.1 0.0 16.4 7 4 8 16 16 16 15 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQS05075.1 - 5.7e-106 333.5 24.8 1.3e-06 28.3 0.0 22.1 20 1 2 22 22 22 21 Ankyrin repeat Ank_5 PF13857.6 OQS05075.1 - 7.9e-102 332.0 27.0 3.6e-10 39.9 0.1 17.6 4 4 15 19 19 19 19 Ankyrin repeats (many copies) Ank PF00023.30 OQS05075.1 - 5.4e-91 295.4 48.7 4.1e-06 27.0 0.1 22.3 21 2 1 22 22 22 20 Ankyrin repeat Shigella_OspC PF06128.11 OQS05075.1 - 0.00033 20.5 5.6 24 4.5 0.0 6.7 6 2 0 7 7 7 0 Shigella flexneri OspC protein DBD_Tnp_Hermes PF10683.9 OQS05075.1 - 0.0011 18.7 0.2 4.4 7.1 0.0 5.9 6 1 1 7 7 7 1 Hermes transposase DNA-binding domain Mic1 PF07035.12 OQS05075.1 - 0.19 11.5 0.0 1.6 8.4 0.0 2.7 2 1 0 2 2 2 0 Colon cancer-associated protein Mic1-like DUF1521 PF07481.11 OQS05075.1 - 0.6 10.1 4.0 4.7 7.2 0.0 4.2 5 1 1 6 6 6 0 Domain of Unknown Function (DUF1521) PDEase_I PF00233.19 OQS05076.1 - 3.9e-66 223.2 2.3 6.8e-66 222.4 2.3 1.4 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase MENTAL PF10457.9 OQS05076.1 - 0.03 14.1 0.9 0.084 12.7 0.9 1.7 1 0 0 1 1 1 0 Cholesterol-capturing domain DivIC PF04977.15 OQS05076.1 - 1.6 8.5 5.8 5.1 6.9 2.0 2.9 3 0 0 3 3 3 0 Septum formation initiator WW PF00397.26 OQS05077.1 - 1.8e-08 34.3 12.9 2.1e-06 27.7 6.1 2.6 2 0 0 2 2 2 2 WW domain IQ PF00612.27 OQS05077.1 - 0.009 15.7 1.8 0.009 15.7 1.8 2.1 2 0 0 2 2 2 1 IQ calmodulin-binding motif Ank_4 PF13637.6 OQS05077.1 - 0.03 14.9 0.0 0.076 13.6 0.0 1.7 1 0 0 1 1 1 0 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQS05077.1 - 0.12 13.0 0.1 0.44 11.3 0.1 2.1 2 0 0 2 2 2 0 Ankyrin repeat BolA PF01722.18 OQS05078.1 - 5.4e-15 55.4 0.0 1.7e-14 53.9 0.0 1.7 1 1 0 1 1 1 1 BolA-like protein Glycos_transf_2 PF00535.26 OQS05079.1 - 4e-16 59.3 0.0 7.6e-16 58.4 0.0 1.6 1 1 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 OQS05079.1 - 0.00023 21.1 0.0 0.00031 20.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 C2 PF00168.30 OQS05080.1 - 6.2e-94 309.1 0.7 2.3e-15 56.7 0.0 8.4 8 0 0 8 8 8 7 C2 domain Pribosyltran PF00156.27 OQS05080.1 - 4.7e-23 81.5 0.0 1.1e-22 80.2 0.0 1.6 1 0 0 1 1 1 1 Phosphoribosyl transferase domain TPR_2 PF07719.17 OQS05080.1 - 1.6e-22 77.7 1.6 2.1e-06 27.4 1.3 5.7 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_1 PF00515.28 OQS05080.1 - 3.4e-22 77.3 1.3 4.5e-06 26.3 1.2 5.8 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_11 PF13414.6 OQS05080.1 - 9.8e-18 63.6 6.2 0.00051 19.7 0.0 5.6 3 2 2 5 5 5 5 TPR repeat TPR_16 PF13432.6 OQS05080.1 - 3.7e-17 62.7 0.2 2.3e-05 25.0 0.0 3.7 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_19 PF14559.6 OQS05080.1 - 6.2e-17 61.9 1.2 3.3e-06 27.5 0.2 4.0 4 0 0 4 4 3 3 Tetratricopeptide repeat TPR_14 PF13428.6 OQS05080.1 - 2e-16 59.2 2.7 0.00058 20.5 0.1 7.1 4 2 3 7 7 6 5 Tetratricopeptide repeat TPR_8 PF13181.6 OQS05080.1 - 4.1e-13 48.4 0.3 0.00059 19.8 0.3 5.4 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_7 PF13176.6 OQS05080.1 - 6.9e-10 38.3 2.1 0.00097 19.0 0.4 5.6 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_17 PF13431.6 OQS05080.1 - 8.4e-10 38.3 4.8 0.021 15.2 0.1 6.0 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_9 PF13371.6 OQS05080.1 - 2.8e-08 33.8 2.1 0.00028 21.0 0.2 3.9 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_12 PF13424.6 OQS05080.1 - 4.8e-08 33.2 5.7 0.0007 19.8 1.2 4.4 3 1 2 5 5 4 3 Tetratricopeptide repeat TPR_6 PF13174.6 OQS05080.1 - 6.7e-06 26.4 0.0 5.7 7.8 0.1 5.4 5 0 0 5 5 5 1 Tetratricopeptide repeat FerI PF08151.12 OQS05080.1 - 1.6e-05 24.9 0.0 5.2e-05 23.2 0.0 2.0 1 0 0 1 1 1 1 FerI (NUC094) domain TPR_10 PF13374.6 OQS05080.1 - 0.0015 18.3 0.6 0.26 11.2 0.5 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_20 PF14561.6 OQS05080.1 - 0.011 16.0 0.7 0.64 10.4 0.0 3.5 3 1 0 3 3 3 0 Tetratricopeptide repeat Ferlin_C PF16165.5 OQS05080.1 - 0.017 15.1 0.1 3.1 7.7 0.0 2.5 2 0 0 2 2 2 0 Ferlin C-terminus U3_snoRNA_assoc PF08297.11 OQS05080.1 - 0.021 15.6 1.9 0.082 13.6 1.9 2.0 1 0 0 1 1 1 0 U3 snoRNA associated LegC3_N PF18654.1 OQS05080.1 - 0.12 11.6 1.2 0.24 10.6 1.2 1.4 1 0 0 1 1 1 0 LegC3 N-terminal coiled-coil domain ANAPC3 PF12895.7 OQS05080.1 - 0.25 11.6 2.5 2.3 8.5 0.1 2.9 3 0 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 Kinesin PF00225.23 OQS05081.1 - 4.5e-112 374.3 0.9 1e-111 373.1 0.9 1.6 1 0 0 1 1 1 1 Kinesin motor domain Methyltransf_16 PF10294.9 OQS05081.1 - 1.2e-28 100.0 0.0 3.3e-28 98.6 0.0 1.7 1 0 0 1 1 1 1 Lysine methyltransferase Microtub_bd PF16796.5 OQS05081.1 - 2.6e-26 92.3 0.1 3e-24 85.7 0.0 2.7 2 0 0 2 2 2 1 Microtubule binding PrmA PF06325.13 OQS05081.1 - 8.2e-09 35.3 0.0 8.2e-09 35.3 0.0 2.6 3 0 0 3 3 3 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 OQS05081.1 - 2.5e-05 23.9 0.4 6.6e-05 22.5 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase small domain HOOK PF05622.12 OQS05081.1 - 3e-05 22.4 25.1 3e-05 22.4 25.1 2.2 1 1 1 2 2 2 1 HOOK protein Methyltransf_25 PF13649.6 OQS05081.1 - 4.7e-05 24.0 0.2 0.00048 20.8 0.0 2.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 OQS05081.1 - 0.00024 20.9 0.2 0.00083 19.2 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Cons_hypoth95 PF03602.15 OQS05081.1 - 0.00053 19.7 0.1 0.0049 16.5 0.0 2.6 2 0 0 2 2 2 1 Conserved hypothetical protein 95 Methyltransf_9 PF08003.11 OQS05081.1 - 0.051 12.5 0.0 0.051 12.5 0.0 3.2 3 1 1 4 4 4 0 Protein of unknown function (DUF1698) Methyltransf_23 PF13489.6 OQS05081.1 - 0.053 13.3 0.0 0.13 12.1 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.12 OQS05081.1 - 0.085 13.5 0.1 0.4 11.4 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_12 PF08242.12 OQS05081.1 - 0.13 13.0 0.0 0.6 10.9 0.0 2.2 1 0 0 1 1 1 0 Methyltransferase domain ApbA_C PF08546.11 OQS05082.1 - 5.1e-30 104.2 0.3 8e-30 103.6 0.3 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.16 OQS05082.1 - 1.7e-21 76.5 0.7 2.8e-21 75.8 0.7 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA F420_oxidored PF03807.17 OQS05082.1 - 0.0018 18.8 3.5 0.51 11.0 0.1 3.3 2 1 1 3 3 3 2 NADP oxidoreductase coenzyme F420-dependent Myb_DNA-binding PF00249.31 OQS05083.1 - 1.5e-30 105.1 1.8 2.3e-16 59.7 0.2 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OQS05083.1 - 9.1e-21 73.9 0.7 1.6e-14 53.8 0.0 2.3 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OQS05083.1 - 7.7e-09 35.3 1.0 3.3e-05 23.7 0.2 2.4 2 0 0 2 2 2 2 Myb DNA-binding like SLIDE PF09111.10 OQS05083.1 - 0.011 15.8 0.0 0.045 13.8 0.0 1.9 2 0 0 2 2 2 0 SLIDE DENN PF02141.21 OQS05084.1 - 8.7e-42 143.2 4.1 1.5e-41 142.4 4.1 1.4 1 0 0 1 1 1 1 DENN (AEX-3) domain AAA PF00004.29 OQS05084.1 - 3.3e-39 134.3 0.0 1e-38 132.7 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) WD40 PF00400.32 OQS05084.1 - 4.6e-30 103.2 26.9 3.2e-06 27.8 1.0 8.8 8 0 0 8 8 8 7 WD domain, G-beta repeat uDENN PF03456.18 OQS05084.1 - 1.1e-11 45.3 0.1 2.9e-11 44.0 0.1 1.8 1 0 0 1 1 1 1 uDENN domain AAA_lid_3 PF17862.1 OQS05084.1 - 1.7e-08 34.2 0.0 4e-08 32.9 0.0 1.6 1 0 0 1 1 1 1 AAA+ lid domain dDENN PF03455.19 OQS05084.1 - 4.6e-06 26.5 0.2 1.2e-05 25.2 0.2 1.7 1 0 0 1 1 1 1 dDENN domain AAA_2 PF07724.14 OQS05084.1 - 2.1e-05 24.7 0.0 0.00013 22.2 0.0 2.2 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) C2 PF00168.30 OQS05084.1 - 0.00052 20.3 0.0 0.0021 18.3 0.0 2.1 2 0 0 2 2 2 1 C2 domain AAA_5 PF07728.14 OQS05084.1 - 0.0011 19.0 0.0 0.0034 17.4 0.0 2.0 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 OQS05084.1 - 0.0042 17.5 0.0 0.036 14.4 0.0 2.4 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 OQS05084.1 - 0.01 16.1 0.0 0.033 14.5 0.0 1.9 1 0 0 1 1 1 0 AAA domain DUF3796 PF12676.7 OQS05084.1 - 0.038 14.4 0.2 0.088 13.2 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3796) DUF815 PF05673.13 OQS05084.1 - 0.038 13.1 0.0 0.074 12.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) RuvB_N PF05496.12 OQS05084.1 - 0.083 12.6 0.0 0.19 11.4 0.0 1.5 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 OQS05084.1 - 0.092 12.9 0.0 0.36 11.0 0.0 2.1 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 OQS05084.1 - 0.11 12.7 0.0 0.21 11.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain Carn_acyltransf PF00755.20 OQS05085.1 - 4.1e-162 540.8 0.0 4.6e-162 540.7 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase Peptidase_M20 PF01546.28 OQS05086.1 - 6.7e-23 81.5 0.1 9.1e-23 81.0 0.1 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 OQS05086.1 - 5.7e-12 45.5 0.1 1.2e-11 44.4 0.1 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain DNA_photolyase PF00875.18 OQS05087.1 - 2.9e-18 66.4 0.0 5.6e-18 65.5 0.0 1.4 1 0 0 1 1 1 1 DNA photolyase UCH PF00443.29 OQS05088.1 - 7.8e-67 225.5 0.7 9.2e-67 225.2 0.0 1.5 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 OQS05088.1 - 1.3e-15 57.9 0.2 7.9e-11 42.1 0.0 3.0 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.12 OQS05088.1 - 4.9e-13 49.5 0.1 4.9e-13 49.5 0.1 2.3 3 0 0 3 3 3 1 DUSP domain EF-hand_7 PF13499.6 OQS05088.1 - 0.061 13.8 0.0 6.7 7.2 0.0 3.1 3 0 0 3 3 3 0 EF-hand domain pair PKD_channel PF08016.12 OQS05089.1 - 1.8e-08 33.5 6.4 1.8e-08 33.5 6.4 2.5 1 1 2 3 3 3 1 Polycystin cation channel BK_channel_a PF03493.18 OQS05090.1 - 3.8e-23 81.5 0.0 6.1e-21 74.4 0.0 2.5 2 0 0 2 2 2 2 Calcium-activated BK potassium channel alpha subunit Castor_Poll_mid PF06241.12 OQS05090.1 - 0.18 11.8 0.0 3 7.8 0.0 2.8 3 0 0 3 3 3 0 Castor and Pollux, part of voltage-gated ion channel TRM PF02005.16 OQS05091.1 - 3.4e-122 408.3 0.1 4.2e-122 408.0 0.1 1.0 1 0 0 1 1 1 1 N2,N2-dimethylguanosine tRNA methyltransferase Zn_ribbon_SprT PF17283.2 OQS05091.1 - 0.037 13.9 1.4 0.091 12.7 1.4 1.7 1 1 0 1 1 1 0 SprT-like zinc ribbon domain Met_10 PF02475.16 OQS05091.1 - 0.081 12.7 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 Met-10+ like-protein Cons_hypoth95 PF03602.15 OQS05091.1 - 0.09 12.4 0.0 0.2 11.3 0.0 1.5 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Zn-ribbon_8 PF09723.10 OQS05091.1 - 0.32 11.2 1.3 1.6 8.9 1.5 2.1 1 1 1 2 2 2 0 Zinc ribbon domain RasGAP_C PF03836.15 OQS05092.1 - 0.0091 16.1 0.8 0.055 13.6 0.4 2.3 1 1 0 1 1 1 1 RasGAP C-terminus Snapin_Pallidin PF14712.6 OQS05092.1 - 0.039 14.4 6.2 0.53 10.7 0.4 2.6 1 1 1 2 2 2 0 Snapin/Pallidin Nsp1_C PF05064.13 OQS05092.1 - 0.08 12.7 0.5 0.08 12.7 0.5 2.1 2 0 0 2 2 2 0 Nsp1-like C-terminal region Vert_HS_TF PF06546.11 OQS05092.1 - 0.084 12.5 5.2 0.23 11.1 5.1 1.7 1 1 0 1 1 1 0 Vertebrate heat shock transcription factor BMFP PF04380.13 OQS05092.1 - 0.13 12.8 0.2 0.13 12.8 0.2 2.8 3 1 2 5 5 5 0 Membrane fusogenic activity BLOC1_2 PF10046.9 OQS05092.1 - 0.2 12.0 4.5 1.4 9.3 0.8 2.3 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 SKA1 PF07160.12 OQS05092.1 - 0.48 10.2 8.5 0.11 12.4 0.5 2.7 1 1 2 3 3 3 0 Spindle and kinetochore-associated protein 1 Occludin_ELL PF07303.13 OQS05092.1 - 1.3 9.8 7.8 23 5.8 0.1 3.2 2 1 0 3 3 3 0 Occludin homology domain DUF3450 PF11932.8 OQS05092.1 - 5.3 6.3 9.6 9.6 5.4 0.4 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) CEBP1_N PF16368.5 OQS05093.1 - 0.014 15.0 1.4 0.021 14.4 1.4 1.2 1 0 0 1 1 1 0 Cytoplasmic polyadenylation element-binding protein 1 N-terminus Adeno_E3_CR2 PF02439.15 OQS05095.1 - 0.019 14.7 4.4 0.032 14.0 4.4 1.3 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 HlyIII PF03006.20 OQS05095.1 - 0.12 12.1 0.2 0.16 11.6 0.2 1.1 1 0 0 1 1 1 0 Haemolysin-III related Ank_2 PF12796.7 OQS05096.1 - 1.6e-54 182.4 14.6 9.4e-14 51.8 0.1 5.0 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank PF00023.30 OQS05096.1 - 1e-44 149.1 6.6 2.4e-05 24.6 0.0 7.3 7 0 0 7 7 7 7 Ankyrin repeat Ank_4 PF13637.6 OQS05096.1 - 1.8e-40 136.8 2.6 1e-10 41.9 0.1 5.5 3 2 3 6 6 6 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQS05096.1 - 5.6e-39 127.7 1.9 0.00022 21.4 0.0 7.9 8 0 0 8 8 8 7 Ankyrin repeat Ank_5 PF13857.6 OQS05096.1 - 1e-23 83.0 12.8 2.1e-07 31.1 0.0 7.0 1 1 7 8 8 8 7 Ankyrin repeats (many copies) VWA_3_C PF18571.1 OQS05096.1 - 0.072 13.0 0.1 4 7.4 0.0 3.6 5 0 0 5 5 5 0 von Willebrand factor type A C-terminal domain PEGA PF08308.11 OQS05096.1 - 0.13 12.2 0.2 8.1 6.4 0.0 3.5 5 0 0 5 5 5 0 PEGA domain DPBB_1 PF03330.18 OQS05097.1 - 1e-06 28.9 0.0 1.8e-06 28.2 0.0 1.4 1 0 0 1 1 1 1 Lytic transglycolase Trypan_PARP PF05887.11 OQS05097.1 - 0.0081 16.1 18.3 0.012 15.6 18.3 1.2 1 0 0 1 1 1 1 Procyclic acidic repetitive protein (PARP) Barwin PF00967.17 OQS05097.1 - 0.0087 15.9 0.1 0.014 15.3 0.1 1.3 1 0 0 1 1 1 1 Barwin family DUF4586 PF15239.6 OQS05098.1 - 2.8e-55 188.6 15.5 5.6e-55 187.7 15.5 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4586) LSM PF01423.22 OQS05098.1 - 1.2e-13 50.6 0.2 2.1e-13 49.8 0.2 1.4 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 OQS05098.1 - 0.15 12.2 0.0 0.39 10.9 0.0 1.7 1 0 0 1 1 1 0 Ataxin 2 SM domain Bacteriocin_IIc PF10439.9 OQS05098.1 - 1.1 9.4 5.3 2.3 8.4 5.3 1.5 1 0 0 1 1 1 0 Bacteriocin class II with double-glycine leader peptide SMN PF06003.12 OQS05099.1 - 2.1e-05 23.9 0.2 4.1e-05 23.0 0.2 1.5 1 1 0 1 1 1 1 Survival motor neuron protein (SMN) DUF4537 PF15057.6 OQS05099.1 - 0.0098 15.9 0.0 4.2 7.4 0.0 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF4537) TUDOR PF00567.24 OQS05099.1 - 0.026 14.5 0.0 0.12 12.4 0.0 2.1 1 1 1 2 2 2 0 Tudor domain DUF996 PF06195.13 OQS05101.1 - 0.0045 17.3 0.3 0.006 16.9 0.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF996) MIOX PF05153.15 OQS05102.1 - 4.1e-90 301.7 2.5 6.4e-90 301.1 2.5 1.3 1 0 0 1 1 1 1 Myo-inositol oxygenase HD PF01966.22 OQS05102.1 - 0.045 14.0 0.1 0.13 12.5 0.1 1.8 2 0 0 2 2 2 0 HD domain MFS_1 PF07690.16 OQS05103.1 - 3.5e-06 26.2 37.2 8.9e-06 24.9 36.7 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily UPF0640 PF15114.6 OQS05103.1 - 0.028 14.2 0.0 0.028 14.2 0.0 1.9 2 0 0 2 2 2 0 Uncharacterised protein family UPF0640 PKcGMP_CC PF16808.5 OQS05104.1 - 0.084 12.7 0.2 0.084 12.7 0.2 8.7 9 0 0 9 9 9 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Mce4_CUP1 PF11887.8 OQS05104.1 - 0.42 10.0 5.3 0.18 11.2 0.2 2.8 2 1 1 3 3 3 0 Cholesterol uptake porter CUP1 of Mce4, putative FYVE PF01363.21 OQS05105.1 - 3.5e-30 103.9 31.8 6.4e-16 58.3 8.3 2.5 3 0 0 3 3 3 2 FYVE zinc finger Zf_RING PF16744.5 OQS05105.1 - 0.25 11.5 24.8 0.082 13.0 5.9 3.5 2 1 1 3 3 3 0 KIAA1045 RING finger Kinesin PF00225.23 OQS05106.1 - 1.6e-116 388.9 0.0 1.6e-116 388.9 0.0 2.9 4 0 0 4 4 4 1 Kinesin motor domain Microtub_bd PF16796.5 OQS05106.1 - 7e-25 87.7 0.0 7e-25 87.7 0.0 2.7 3 1 0 3 3 3 1 Microtubule binding Kinesin_assoc PF16183.5 OQS05106.1 - 0.014 15.5 1.4 0.014 15.5 1.4 3.6 1 1 0 2 2 2 0 Kinesin-associated Kinesin PF00225.23 OQS05107.1 - 3.7e-89 299.0 4.6 9.3e-89 297.6 4.6 1.7 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 OQS05107.1 - 6.4e-20 71.6 5.3 7.5e-19 68.1 0.2 3.6 3 0 0 3 3 3 1 Microtubule binding AAA_7 PF12775.7 OQS05107.1 - 0.025 14.1 0.0 5.6 6.4 0.0 2.5 2 0 0 2 2 2 0 P-loop containing dynein motor region Troponin PF00992.20 OQS05107.1 - 1.8 8.9 16.4 0.72 10.1 7.9 3.0 3 0 0 3 3 3 0 Troponin DUF4407 PF14362.6 OQS05107.1 - 6.9 5.9 11.3 1.4 8.3 5.8 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4407) adh_short PF00106.25 OQS05108.1 - 5.3e-41 140.2 6.8 9.3e-41 139.4 6.8 1.4 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OQS05108.1 - 8.8e-34 117.1 5.0 2e-33 115.9 5.0 1.6 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OQS05108.1 - 8e-16 58.5 1.2 1.2e-15 57.8 1.2 1.2 1 0 0 1 1 1 1 KR domain PLDc_2 PF13091.6 OQS05109.1 - 1.8e-26 92.6 2.0 2.6e-11 43.6 0.0 4.0 4 0 0 4 4 4 2 PLD-like domain PLDc PF00614.22 OQS05109.1 - 1.7e-07 31.1 15.0 0.0033 17.5 0.9 5.2 4 1 0 4 4 4 3 Phospholipase D Active site motif Antig_Caf1 PF09255.10 OQS05109.1 - 0.057 13.5 0.3 4.2 7.5 0.0 2.7 2 0 0 2 2 2 0 Caf1 Capsule antigen GSP_synth PF03738.14 OQS05110.1 - 1.1e-67 228.9 0.0 1.5e-67 228.5 0.0 1.0 1 0 0 1 1 1 1 Glutathionylspermidine synthase preATP-grasp CotH PF08757.11 OQS05111.1 - 7.1e-30 104.6 0.0 2.4e-29 102.9 0.0 1.7 1 1 0 1 1 1 1 CotH kinase protein EGF_2 PF07974.13 OQS05111.1 - 1.1 9.7 9.5 2.6 8.5 9.5 1.6 1 0 0 1 1 1 0 EGF-like domain TRAPPC10 PF12584.8 OQS05113.1 - 0.031 14.0 0.0 0.059 13.1 0.0 1.4 1 0 0 1 1 1 0 Trafficking protein particle complex subunit 10, TRAPPC10 MMS1_N PF10433.9 OQS05115.1 - 1.2e-136 456.2 0.0 3.8e-136 454.6 0.0 1.7 2 0 0 2 2 2 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.15 OQS05115.1 - 2.9e-88 296.3 0.0 3.1e-87 292.9 0.0 2.4 2 0 0 2 2 2 1 CPSF A subunit region Ank_2 PF12796.7 OQS05116.1 - 4e-24 85.0 12.3 1.7e-07 31.7 0.1 5.6 2 1 3 5 5 5 4 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OQS05116.1 - 3e-17 62.5 15.1 0.0037 17.6 0.3 10.0 3 1 8 11 11 11 6 Ankyrin repeats (many copies) Ank_4 PF13637.6 OQS05116.1 - 7.5e-17 61.5 9.6 2e-06 28.2 0.1 5.5 4 1 0 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQS05116.1 - 1.2e-10 40.7 4.8 2.7 8.8 0.0 9.2 7 2 3 10 10 10 2 Ankyrin repeat DUF5049 PF16468.5 OQS05116.1 - 5.1e-06 26.3 5.9 9.3 6.2 0.0 6.8 5 2 3 8 8 8 2 Domain of unknown function (DUF5049) Ank PF00023.30 OQS05116.1 - 0.23 12.0 6.1 2.2e+02 2.6 0.0 6.8 3 1 4 7 7 7 0 Ankyrin repeat MFS_1 PF07690.16 OQS05117.1 - 4.5e-14 52.2 42.9 3.8e-10 39.2 20.7 2.2 1 1 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 OQS05117.1 - 5.7e-08 32.1 7.4 5.7e-08 32.1 7.4 2.3 2 0 0 2 2 2 1 Sugar (and other) transporter Sec1 PF00995.23 OQS05118.1 - 1.4e-53 183.0 0.0 1.6e-53 182.8 0.0 1.1 1 0 0 1 1 1 1 Sec1 family Glyco_hydro_31 PF01055.26 OQS05119.1 - 1.2e-143 479.5 3.7 1.6e-143 479.1 3.7 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 NtCtMGAM_N PF16863.5 OQS05119.1 - 1.1e-28 99.8 0.0 2.7e-28 98.5 0.0 1.7 1 0 0 1 1 1 1 N-terminal barrel of NtMGAM and CtMGAM, maltase-glucoamylase Trefoil PF00088.18 OQS05119.1 - 8.7e-12 44.7 17.3 1.1e-07 31.7 2.9 2.8 3 0 0 3 3 3 2 Trefoil (P-type) domain Gal_mutarotas_2 PF13802.6 OQS05119.1 - 1e-07 32.2 0.7 3.6e-07 30.4 0.5 2.1 2 0 0 2 2 2 1 Galactose mutarotase-like Pkinase PF00069.25 OQS05120.1 - 2.8e-66 223.6 0.0 3.3e-66 223.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQS05120.1 - 2.1e-36 125.5 0.0 2.6e-36 125.2 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OQS05120.1 - 4.6e-07 29.4 0.0 1.6e-06 27.7 0.0 1.8 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 OQS05120.1 - 7.1e-07 28.3 0.0 1.1e-06 27.7 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 OQS05120.1 - 0.0016 18.4 0.1 0.0023 17.9 0.1 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 OQS05120.1 - 0.053 12.9 0.0 0.079 12.3 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 OQS05120.1 - 0.069 12.7 0.1 0.17 11.5 0.0 1.5 1 1 0 1 1 1 0 Choline/ethanolamine kinase Pkinase_Tyr PF07714.17 OQS05121.1 - 1.4e-29 103.2 0.0 4.8e-28 98.1 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OQS05121.1 - 4.7e-24 85.2 0.0 3.4e-23 82.3 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain DUF87 PF01935.17 OQS05122.1 - 0.038 14.1 1.3 0.063 13.4 1.3 1.3 1 0 0 1 1 1 0 Helicase HerA, central domain RecG_N PF17190.4 OQS05122.1 - 0.047 14.4 2.5 0.047 14.4 2.5 1.9 2 0 0 2 2 2 0 RecG N-terminal helical domain LAMTOR PF15454.6 OQS05122.1 - 5.3 7.7 6.8 0.48 11.1 0.8 2.3 2 1 0 2 2 2 0 Late endosomal/lysosomal adaptor and MAPK and MTOR activator PH PF00169.29 OQS05123.1 - 5.1e-10 39.8 0.1 7.6e-10 39.3 0.1 1.2 1 0 0 1 1 1 1 PH domain PH_8 PF15409.6 OQS05123.1 - 1.1e-05 25.6 0.2 1.9e-05 24.8 0.2 1.4 1 1 0 1 1 1 1 Pleckstrin homology domain PH_11 PF15413.6 OQS05123.1 - 0.00022 21.6 5.2 0.031 14.7 5.2 2.1 1 1 0 1 1 1 1 Pleckstrin homology domain PDZ PF00595.24 OQS05124.1 - 8.4e-15 54.9 0.1 0.00011 22.5 0.0 4.2 4 0 0 4 4 4 3 PDZ domain PDZ_6 PF17820.1 OQS05124.1 - 9.3e-14 51.0 0.1 2.1e-05 24.3 0.0 4.0 4 0 0 4 4 4 2 PDZ domain PDZ_2 PF13180.6 OQS05124.1 - 5.1e-07 29.9 0.6 0.45 10.9 0.0 3.6 4 0 0 4 4 4 3 PDZ domain PDZ_4 PF17816.1 OQS05124.1 - 0.029 14.8 0.2 3.4 8.1 0.0 3.0 3 0 0 3 3 3 0 PDZ domain DUF829 PF05705.14 OQS05125.1 - 7e-34 117.8 0.6 1.1e-33 117.2 0.6 1.3 1 1 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) BAAT_C PF08840.11 OQS05125.1 - 0.0026 17.7 0.6 0.0052 16.7 0.1 1.7 2 0 0 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal Peptidase_S9 PF00326.21 OQS05125.1 - 0.013 14.9 0.2 0.02 14.4 0.2 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family GlcNAc PF11397.8 OQS05126.1 - 2e-49 168.9 0.0 1.1e-42 146.8 0.0 2.2 1 1 1 2 2 2 2 Glycosyltransferase (GlcNAc) COesterase PF00135.28 OQS05126.1 - 9.5e-16 57.7 0.1 1.6e-15 57.0 0.1 1.2 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 OQS05126.1 - 1e-09 38.6 0.1 1.8e-09 37.8 0.1 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Chlorophyllase2 PF12740.7 OQS05126.1 - 2.9e-05 23.1 0.0 4.7e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme Abhydrolase_6 PF12697.7 OQS05126.1 - 8.8e-05 23.2 0.3 0.00028 21.6 0.3 1.9 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 OQS05126.1 - 0.00023 20.5 0.7 0.2 10.9 0.4 2.7 2 1 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_2 PF02230.16 OQS05126.1 - 0.0055 16.5 0.5 0.38 10.5 0.0 2.7 2 1 0 3 3 3 1 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.21 OQS05126.1 - 0.0081 15.7 0.0 0.02 14.4 0.0 1.6 2 0 0 2 2 2 1 Prolyl oligopeptidase family Chlorophyllase PF07224.11 OQS05126.1 - 0.025 13.6 0.1 0.039 13.0 0.1 1.2 1 0 0 1 1 1 0 Chlorophyllase Abhydrolase_1 PF00561.20 OQS05126.1 - 0.027 14.1 0.3 2.1 7.9 0.1 2.3 2 0 0 2 2 2 0 alpha/beta hydrolase fold Glyco_transf_92 PF01697.27 OQS05127.1 - 0.024 14.3 1.0 0.025 14.2 1.0 1.0 1 0 0 1 1 1 0 Glycosyltransferase family 92 PDZ_6 PF17820.1 OQS05129.1 - 0.00011 21.9 0.0 0.1 12.4 0.0 2.5 2 0 0 2 2 2 2 PDZ domain PDZ PF00595.24 OQS05129.1 - 0.00021 21.6 0.1 0.018 15.4 0.1 2.2 2 0 0 2 2 2 2 PDZ domain DUF29 PF01724.16 OQS05130.1 - 0.19 12.0 5.4 0.14 12.3 4.6 1.4 1 1 0 1 1 1 0 Domain of unknown function DUF29 LMBR1 PF04791.16 OQS05130.1 - 0.51 9.2 2.3 0.49 9.2 2.3 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein IQ PF00612.27 OQS05132.1 - 0.0002 20.8 2.1 0.00062 19.3 2.1 1.9 1 0 0 1 1 1 1 IQ calmodulin-binding motif Myb_DNA-binding PF00249.31 OQS05134.1 - 5.6e-10 39.2 0.1 9.8e-10 38.5 0.1 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OQS05134.1 - 0.0097 16.1 0.1 0.021 15.1 0.1 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain TPR_12 PF13424.6 OQS05136.1 - 2.5e-09 37.3 9.9 8.6e-07 29.2 3.8 3.2 2 1 2 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.17 OQS05136.1 - 0.00048 20.0 8.2 1.9 8.8 0.3 4.9 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_8 PF13181.6 OQS05136.1 - 0.0047 17.0 4.3 3.3 8.2 0.1 4.2 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 OQS05136.1 - 0.013 16.3 5.5 7.1 7.7 0.2 4.8 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_10 PF13374.6 OQS05136.1 - 0.036 13.9 0.2 0.036 13.9 0.2 3.7 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_1 PF00515.28 OQS05136.1 - 0.046 13.6 5.0 0.36 10.7 0.2 4.1 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_7 PF13176.6 OQS05136.1 - 0.1 12.7 1.5 22 5.4 0.1 3.7 5 0 0 5 5 5 0 Tetratricopeptide repeat DUF3856 PF12968.7 OQS05136.1 - 0.23 11.5 2.6 0.65 10.1 0.1 2.7 2 1 1 3 3 3 0 Domain of Unknown Function (DUF3856) TPR_19 PF14559.6 OQS05136.1 - 0.32 11.6 4.7 2 9.0 1.6 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat EF-hand_7 PF13499.6 OQS05137.1 - 6.6e-33 113.0 19.1 9.2e-12 45.3 0.1 5.6 5 0 0 5 5 4 3 EF-hand domain pair EF-hand_1 PF00036.32 OQS05137.1 - 7e-33 109.7 14.1 4.3e-06 25.9 0.0 7.6 7 0 0 7 7 7 6 EF hand CoA_binding PF02629.19 OQS05137.1 - 6.9e-31 106.8 1.1 6.9e-31 106.8 1.1 1.9 2 0 0 2 2 1 1 CoA binding domain Metallophos PF00149.28 OQS05137.1 - 6.3e-29 101.9 0.0 1.4e-28 100.8 0.0 1.7 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase EF-hand_6 PF13405.6 OQS05137.1 - 7.3e-26 87.9 19.3 5.6e-06 25.9 0.1 7.4 7 0 0 7 7 6 6 EF-hand domain EF-hand_8 PF13833.6 OQS05137.1 - 5.3e-25 87.0 15.3 1.1e-06 28.4 0.8 6.7 4 3 2 7 7 7 6 EF-hand domain pair Ligase_CoA PF00549.19 OQS05137.1 - 1.2e-23 83.6 0.1 2.2e-23 82.8 0.1 1.4 1 0 0 1 1 1 1 CoA-ligase EF-hand_5 PF13202.6 OQS05137.1 - 2.4e-15 55.2 25.4 0.00021 20.6 0.1 6.5 7 0 0 7 7 6 4 EF hand EF-hand_11 PF08976.11 OQS05137.1 - 3.9e-13 50.2 8.7 0.0022 18.8 0.0 5.1 4 1 1 5 5 5 3 EF-hand domain CAP_GLY PF01302.25 OQS05137.1 - 4.2e-13 49.1 0.2 8.6e-13 48.1 0.2 1.6 1 0 0 1 1 1 1 CAP-Gly domain CCT PF06203.14 OQS05137.1 - 8.7e-12 44.9 5.0 8.7e-12 44.9 5.0 2.4 2 0 0 2 2 2 1 CCT motif Succ_CoA_lig PF13607.6 OQS05137.1 - 1.7e-07 31.1 0.0 3.6e-07 30.1 0.0 1.5 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain EF-hand_4 PF12763.7 OQS05137.1 - 2.9e-07 30.4 9.8 0.00052 19.9 1.1 5.1 3 1 2 5 5 5 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 OQS05137.1 - 0.00044 20.5 5.6 2.6 8.4 0.1 5.1 4 0 0 4 4 4 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_9 PF14658.6 OQS05137.1 - 0.014 15.7 0.3 0.12 12.8 0.2 2.7 2 0 0 2 2 2 0 EF-hand domain PPP5 PF08321.12 OQS05137.1 - 0.031 14.5 0.0 0.17 12.2 0.0 2.4 1 0 0 1 1 1 0 PPP5 TPR repeat region EF-hand_10 PF14788.6 OQS05137.1 - 0.25 11.2 1.1 0.74 9.7 0.2 2.4 2 0 0 2 2 1 0 EF hand PDZ PF00595.24 OQS05138.1 - 2.9e-12 46.7 0.1 2.4e-06 27.8 0.0 2.8 2 0 0 2 2 2 2 PDZ domain ANAPC4_WD40 PF12894.7 OQS05138.1 - 5.9e-12 45.7 0.1 0.01 16.1 0.0 5.5 4 2 2 6 6 5 3 Anaphase-promoting complex subunit 4 WD40 domain PDZ_6 PF17820.1 OQS05138.1 - 2.6e-10 40.0 0.0 6.2e-07 29.2 0.0 2.8 2 0 0 2 2 2 2 PDZ domain Synaptobrevin PF00957.21 OQS05138.1 - 3.5e-06 26.7 0.1 8.2e-06 25.5 0.1 1.6 1 0 0 1 1 1 1 Synaptobrevin PDZ_2 PF13180.6 OQS05138.1 - 0.00022 21.5 0.2 0.0036 17.6 0.0 2.9 3 0 0 3 3 3 1 PDZ domain Lgl_C PF08596.10 OQS05138.1 - 0.0012 17.6 0.7 0.3 9.7 0.0 2.7 3 0 0 3 3 3 2 Lethal giant larvae(Lgl) like, C-terminal BBS2_Mid PF14783.6 OQS05138.1 - 0.0096 16.0 0.0 0.3 11.1 0.0 3.3 3 0 0 3 3 3 1 Ciliary BBSome complex subunit 2, middle region WD40 PF00400.32 OQS05138.1 - 0.022 15.6 4.3 17 6.5 0.0 5.6 7 0 0 7 7 5 0 WD domain, G-beta repeat Tricorn_PDZ PF14685.6 OQS05138.1 - 0.03 14.3 0.1 0.14 12.1 0.0 2.1 2 0 0 2 2 2 0 Tricorn protease PDZ domain Utp8 PF10395.9 OQS05138.1 - 0.05 12.1 1.5 0.091 11.2 0.5 1.9 2 0 0 2 2 2 0 Utp8 family HPS3_N PF14761.6 OQS05138.1 - 0.073 12.6 1.5 2.2 7.7 0.2 3.5 2 1 0 3 3 3 0 Hermansky-Pudlak syndrome 3 TPR_MLP1_2 PF07926.12 OQS05139.1 - 0.03 14.4 73.7 0.32 11.1 19.7 4.7 2 2 2 4 4 4 0 TPR/MLP1/MLP2-like protein ATG16 PF08614.11 OQS05139.1 - 0.11 12.7 78.6 4.2 7.5 10.5 4.9 2 2 1 3 3 3 0 Autophagy protein 16 (ATG16) Filament PF00038.21 OQS05139.1 - 0.15 11.6 66.6 0.74 9.3 13.6 4.4 2 1 2 4 4 4 0 Intermediate filament protein Fez1 PF06818.15 OQS05139.1 - 0.22 12.0 65.1 0.082 13.3 22.3 3.9 1 1 2 3 3 3 0 Fez1 Spc7 PF08317.11 OQS05139.1 - 0.37 9.6 68.2 0.015 14.2 22.4 3.8 1 1 1 3 3 3 0 Spc7 kinetochore protein APG6_N PF17675.1 OQS05139.1 - 0.66 10.5 81.8 0.2 12.2 18.3 5.2 1 1 3 5 5 5 0 Apg6 coiled-coil region Atg14 PF10186.9 OQS05139.1 - 2.3 7.2 64.4 0.11 11.6 23.0 3.5 1 1 2 3 3 3 0 Vacuolar sorting 38 and autophagy-related subunit 14 Mito_carr PF00153.27 OQS05140.1 - 3.7e-67 222.3 3.3 9.6e-22 76.7 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Hydrolase_4 PF12146.8 OQS05141.1 - 5.6e-13 48.7 0.2 1e-11 44.6 0.1 2.1 1 1 1 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 OQS05141.1 - 1.1e-08 35.0 0.2 2e-06 27.7 0.3 2.2 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 OQS05141.1 - 1.3e-06 29.2 0.0 1.9e-06 28.6 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family FSH1 PF03959.13 OQS05141.1 - 1.1e-05 25.2 0.0 2e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Peptidase_S15 PF02129.18 OQS05141.1 - 3.1e-05 23.7 0.0 0.00054 19.6 0.0 2.2 1 1 1 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) AXE1 PF05448.12 OQS05141.1 - 0.0014 17.4 0.0 0.83 8.3 0.0 2.1 1 1 1 2 2 2 2 Acetyl xylan esterase (AXE1) DLH PF01738.18 OQS05141.1 - 0.02 14.5 0.0 0.88 9.1 0.0 2.4 2 1 0 2 2 2 0 Dienelactone hydrolase family Peptidase_S9 PF00326.21 OQS05141.1 - 0.021 14.3 0.1 0.13 11.7 0.1 1.9 1 1 0 1 1 1 0 Prolyl oligopeptidase family Say1_Mug180 PF10340.9 OQS05141.1 - 0.028 13.3 0.0 0.048 12.5 0.0 1.3 1 0 0 1 1 1 0 Steryl acetyl hydrolase BAAT_C PF08840.11 OQS05141.1 - 0.032 14.1 0.0 0.055 13.4 0.0 1.4 1 1 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Esterase PF00756.20 OQS05141.1 - 0.17 11.5 0.0 0.47 10.0 0.0 1.6 2 0 0 2 2 2 0 Putative esterase RGS PF00615.19 OQS05142.1 - 3.8e-25 88.5 6.2 2.4e-15 56.8 0.1 2.2 2 0 0 2 2 2 2 Regulator of G protein signaling domain NB-ARC PF00931.22 OQS05142.1 - 0.007 15.6 0.6 0.015 14.5 0.6 1.6 1 1 0 1 1 1 1 NB-ARC domain AAA_assoc PF14363.6 OQS05142.1 - 0.022 15.1 0.1 0.13 12.6 0.1 2.2 2 0 0 2 2 2 0 Domain associated at C-terminal with AAA Astacin PF01400.24 OQS05143.1 - 1.4e-27 96.5 0.3 2.5e-27 95.7 0.3 1.4 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) PAP_central PF04928.17 OQS05144.1 - 0.0015 17.6 2.2 0.03 13.3 0.0 3.1 3 1 0 3 3 3 1 Poly(A) polymerase central domain PAP_assoc PF03828.19 OQS05144.1 - 0.0071 16.5 0.0 0.024 14.8 0.0 2.0 1 0 0 1 1 1 1 Cid1 family poly A polymerase NRN1 PF15056.6 OQS05144.1 - 0.078 13.1 0.1 0.25 11.5 0.1 1.9 1 0 0 1 1 1 0 Neuritin protein family PIP5K PF01504.18 OQS05145.1 - 7.8e-71 238.5 0.4 1.4e-70 237.7 0.4 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase Pkinase PF00069.25 OQS05145.1 - 4.4e-62 209.8 0.0 6.8e-62 209.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain cNMP_binding PF00027.29 OQS05145.1 - 9.3e-52 173.1 0.6 3.8e-18 65.3 0.0 3.7 3 0 0 3 3 3 3 Cyclic nucleotide-binding domain Pkinase_Tyr PF07714.17 OQS05145.1 - 7.2e-29 100.8 0.0 1.1e-28 100.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase 7tm_2 PF00002.24 OQS05145.1 - 7.3e-08 32.0 3.9 2.5e-07 30.3 3.9 1.9 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) Kinase-like PF14531.6 OQS05145.1 - 0.0048 16.3 0.0 0.021 14.2 0.0 2.0 2 0 0 2 2 2 1 Kinase-like zf-BED PF02892.15 OQS05145.1 - 0.13 12.3 0.9 0.35 10.9 0.9 1.7 1 0 0 1 1 1 0 BED zinc finger EbsA PF17255.2 OQS05145.1 - 0.33 11.3 3.3 19 5.6 0.1 2.6 2 0 0 2 2 2 0 EbsA-like protein DUF3180 PF11377.8 OQS05145.1 - 0.89 9.7 4.1 0.51 10.5 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3180) 7tm_1 PF00001.21 OQS05145.1 - 6.4 6.0 13.5 24 4.1 13.5 2.1 1 1 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) SET PF00856.28 OQS05146.1 - 2.5e-09 37.8 0.4 2.8e-06 27.8 0.2 2.2 1 1 1 2 2 2 2 SET domain WD40 PF00400.32 OQS05147.1 - 1.6e-13 50.9 9.5 4.5e-05 24.1 0.0 8.2 10 0 0 10 10 10 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OQS05147.1 - 2.4e-11 43.8 0.0 0.16 12.3 0.0 7.5 5 2 2 7 7 7 3 Anaphase-promoting complex subunit 4 WD40 domain CENP-B_dimeris PF09026.10 OQS05147.1 - 0.16 12.3 10.2 0.53 10.7 10.2 1.9 1 0 0 1 1 1 0 Centromere protein B dimerisation domain XkdW PF09636.10 OQS05147.1 - 4.6 7.4 7.1 0.64 10.1 0.7 3.0 2 0 0 2 2 2 0 XkdW protein NAPRTase_N PF17767.1 OQS05147.1 - 8.7 6.7 9.0 3.5 8.0 0.1 4.1 3 1 0 4 4 4 0 Nicotinate phosphoribosyltransferase (NAPRTase) N-terminal domain bZIP_1 PF00170.21 OQS05149.1 - 3e-06 27.2 10.1 5.6e-06 26.4 10.1 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_Maf PF03131.17 OQS05149.1 - 0.00038 20.9 5.0 0.00073 20.0 5.0 1.4 1 0 0 1 1 1 1 bZIP Maf transcription factor bZIP_2 PF07716.15 OQS05149.1 - 0.00046 20.2 8.2 0.00082 19.4 8.2 1.4 1 0 0 1 1 1 1 Basic region leucine zipper PHD_4 PF16866.5 OQS05149.1 - 4.8 7.4 7.1 5.8 7.1 1.9 3.0 2 1 0 2 2 2 0 PHD-finger Arm PF00514.23 OQS05150.1 - 2.9e-32 109.7 16.4 1.4e-09 37.7 0.0 8.7 9 0 0 9 9 9 4 Armadillo/beta-catenin-like repeat HEAT PF02985.22 OQS05150.1 - 8.8e-19 66.0 7.2 0.021 15.0 0.0 8.3 7 0 0 7 7 7 4 HEAT repeat HEAT_2 PF13646.6 OQS05150.1 - 4.2e-15 55.9 13.5 0.0022 18.3 0.4 6.0 2 2 4 6 6 6 5 HEAT repeats Cnd1 PF12717.7 OQS05150.1 - 1.5e-12 47.9 1.0 0.027 14.5 0.0 4.7 2 2 3 5 5 5 3 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 OQS05150.1 - 3.8e-11 43.2 20.5 0.0011 19.5 0.4 7.2 6 2 2 8 8 8 6 HEAT-like repeat DNA_alkylation PF08713.11 OQS05150.1 - 3.4e-08 33.5 0.1 0.092 12.4 0.0 4.4 4 1 0 5 5 5 3 DNA alkylation repair enzyme Adaptin_N PF01602.20 OQS05150.1 - 5.4e-07 28.5 4.2 0.014 14.0 0.1 3.4 2 1 1 3 3 3 2 Adaptin N terminal region CHASE6_C PF17150.4 OQS05150.1 - 2.4e-06 28.1 0.7 51 4.6 0.0 6.8 7 0 0 7 7 6 0 C-terminal domain of two-partite extracellular sensor domain CLASP_N PF12348.8 OQS05150.1 - 6.2e-06 25.9 1.5 0.18 11.3 0.0 3.7 3 1 0 3 3 3 2 CLASP N terminal Atx10homo_assoc PF09759.9 OQS05150.1 - 0.00016 21.6 2.0 0.86 9.7 0.3 5.2 5 1 2 7 7 6 1 Spinocerebellar ataxia type 10 protein domain Proteasom_PSMB PF10508.9 OQS05150.1 - 0.00024 19.8 2.2 0.0039 15.8 0.1 3.2 2 1 2 4 4 4 1 Proteasome non-ATPase 26S subunit PPR_long PF17177.4 OQS05150.1 - 0.00097 18.6 0.1 0.004 16.5 0.1 2.1 1 0 0 1 1 1 1 Pentacotripeptide-repeat region of PRORP RICTOR_V PF14668.6 OQS05150.1 - 0.0016 18.7 0.1 2.4 8.5 0.0 4.0 4 0 0 4 4 4 1 Rapamycin-insensitive companion of mTOR, domain 5 V-ATPase_H_C PF11698.8 OQS05150.1 - 0.0026 17.9 1.8 10 6.2 0.0 4.7 4 1 1 5 5 5 0 V-ATPase subunit H PPR_2 PF13041.6 OQS05150.1 - 0.0073 16.5 0.6 0.61 10.3 0.0 3.0 2 1 1 3 3 3 2 PPR repeat family HEAT_UF PF18817.1 OQS05150.1 - 0.0077 16.5 0.2 2 8.8 0.0 4.4 5 0 0 5 5 4 1 Repeat of uncharacterized protein PH0542 PPR PF01535.20 OQS05150.1 - 0.038 14.2 0.4 8.5 6.9 0.0 3.6 4 0 0 4 4 4 0 PPR repeat Mo25 PF08569.11 OQS05150.1 - 0.043 13.2 0.1 1.9 7.7 0.1 2.9 1 1 1 2 2 2 0 Mo25-like Npa1 PF11707.8 OQS05150.1 - 0.049 13.0 0.1 3.7 6.8 0.0 2.9 2 0 0 2 2 2 0 Ribosome 60S biogenesis N-terminal FAD-oxidase_C PF02913.19 OQS05151.1 - 2e-45 155.4 0.0 2.8e-45 154.9 0.0 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 OQS05151.1 - 1.5e-38 131.7 0.3 2.9e-38 130.7 0.3 1.5 1 0 0 1 1 1 1 FAD binding domain DUF3271 PF11675.8 OQS05151.1 - 0.15 11.3 0.0 0.26 10.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3271) EF-hand_7 PF13499.6 OQS05152.1 - 4.2e-18 65.6 3.7 3.7e-06 27.3 1.1 6.0 6 0 0 6 6 6 3 EF-hand domain pair EF-hand_1 PF00036.32 OQS05152.1 - 6e-16 56.7 5.0 0.00012 21.4 0.2 8.1 7 0 0 7 7 7 4 EF hand EF-hand_8 PF13833.6 OQS05152.1 - 8.2e-14 51.2 0.3 1.1e-06 28.4 0.4 4.1 4 1 1 5 5 5 3 EF-hand domain pair EF-hand_6 PF13405.6 OQS05152.1 - 2.1e-13 49.0 10.3 0.00029 20.5 0.3 8.6 7 1 0 7 7 7 4 EF-hand domain EF-hand_5 PF13202.6 OQS05152.1 - 1.2e-05 24.5 9.0 0.0039 16.6 0.1 5.4 7 0 0 7 7 7 2 EF hand zf-RanBP PF00641.18 OQS05152.1 - 0.0074 15.6 3.0 0.0074 15.6 3.0 2.8 2 0 0 2 2 2 1 Zn-finger in Ran binding protein and others DZR PF12773.7 OQS05152.1 - 0.11 12.5 9.7 0.68 10.0 2.3 2.7 2 0 0 2 2 2 0 Double zinc ribbon zf-MIZ PF02891.20 OQS05152.1 - 0.41 10.4 3.4 1.2 9.0 0.2 3.2 3 0 0 3 3 3 0 MIZ/SP-RING zinc finger Vps36-NZF-N PF16988.5 OQS05152.1 - 3 7.3 13.9 1.1 8.7 0.7 3.4 1 1 1 2 2 2 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain Sec7 PF01369.20 OQS05153.1 - 3.7e-51 173.4 0.0 7.8e-51 172.4 0.0 1.6 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.7 OQS05153.1 - 5.2e-18 65.5 0.2 1.9e-17 63.6 0.2 2.1 1 0 0 1 1 1 1 Guanine nucleotide exchange factor in Golgi transport N-terminal MinE PF03776.14 OQS05154.1 - 1.4e-15 57.1 0.2 1.8e-15 56.7 0.2 1.1 1 0 0 1 1 1 1 Septum formation topological specificity factor MinE BRCT PF00533.26 OQS05157.1 - 9e-09 35.6 0.0 0.0051 17.2 0.0 2.5 2 0 0 2 2 2 2 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 OQS05157.1 - 6.9e-06 26.4 0.0 0.16 12.4 0.0 2.6 2 0 0 2 2 2 2 BRCT domain, a BRCA1 C-terminus domain zf-C3HC4_2 PF13923.6 OQS05157.1 - 4.1e-05 23.3 10.7 0.00013 21.8 10.7 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OQS05157.1 - 5e-05 23.2 6.9 0.00014 21.8 6.9 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 OQS05157.1 - 8.7e-05 22.3 11.5 0.0002 21.2 11.5 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OQS05157.1 - 0.00027 20.9 10.4 0.00061 19.7 10.4 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 OQS05157.1 - 0.00081 19.5 6.3 0.0018 18.4 6.3 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.6 OQS05157.1 - 0.0011 19.2 10.0 0.016 15.6 10.5 2.5 2 1 0 2 2 2 1 Ring finger domain zf-RING_4 PF14570.6 OQS05157.1 - 0.014 15.2 4.2 0.033 14.0 4.2 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain RTT107_BRCT_5 PF16770.5 OQS05157.1 - 0.032 14.1 0.0 0.08 12.8 0.0 1.7 1 0 0 1 1 1 0 Regulator of Ty1 transposition protein 107 BRCT domain zf-C3HC4_3 PF13920.6 OQS05157.1 - 0.034 14.0 7.5 0.069 13.0 7.5 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) BRCT_3 PF18428.1 OQS05157.1 - 0.036 14.1 0.0 0.1 12.6 0.0 1.8 1 0 0 1 1 1 0 BRCA1 C Terminus (BRCT) domain zf-rbx1 PF12678.7 OQS05157.1 - 0.28 11.5 8.8 0.91 9.9 8.8 1.9 1 0 0 1 1 1 0 RING-H2 zinc finger domain Prok-RING_4 PF14447.6 OQS05157.1 - 0.29 11.0 7.3 0.63 9.9 7.3 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_10 PF16685.5 OQS05157.1 - 0.42 10.8 7.8 0.22 11.7 4.9 2.0 2 0 0 2 2 2 0 zinc RING finger of MSL2 DUF1272 PF06906.11 OQS05157.1 - 1.1 9.4 6.3 2.3 8.3 6.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) OrsD PF12013.8 OQS05158.1 - 0.001 19.5 27.4 0.21 12.0 0.0 7.0 8 0 0 8 8 8 3 Orsellinic acid/F9775 biosynthesis cluster protein D zf-C2H2 PF00096.26 OQS05158.1 - 0.046 14.2 0.4 0.046 14.2 0.4 6.9 7 0 0 7 7 7 0 Zinc finger, C2H2 type TF_Zn_Ribbon PF08271.12 OQS05158.1 - 0.083 12.4 1.2 7.5 6.2 0.1 2.8 2 0 0 2 2 2 0 TFIIB zinc-binding Ogr_Delta PF04606.12 OQS05158.1 - 0.35 10.9 0.0 0.35 10.9 0.0 5.0 6 0 0 6 6 6 0 Ogr/Delta-like zinc finger His_kinase PF06580.13 OQS05159.1 - 0.068 13.5 0.3 0.17 12.3 0.3 1.6 1 0 0 1 1 1 0 Histidine kinase FYVE PF01363.21 OQS05160.1 - 3.8e-08 33.3 12.9 7.9e-08 32.3 12.9 1.5 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.16 OQS05160.1 - 0.0019 18.4 7.0 0.0047 17.1 7.0 1.7 1 0 0 1 1 1 1 FYVE-type zinc finger DUF2321 PF10083.9 OQS05160.1 - 3.4 7.3 8.8 3 7.4 5.5 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2321) Pkinase PF00069.25 OQS05161.1 - 6.2e-60 202.8 0.0 2.5e-59 200.8 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQS05161.1 - 2.1e-35 122.2 0.0 3.8e-35 121.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase PH PF00169.29 OQS05161.1 - 5.4e-12 46.2 0.2 8.8e-11 42.2 0.1 2.5 2 0 0 2 2 2 1 PH domain PH_11 PF15413.6 OQS05161.1 - 0.00075 19.9 0.1 0.002 18.5 0.1 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain Kinase-like PF14531.6 OQS05161.1 - 0.0018 17.7 0.0 0.0051 16.2 0.0 1.7 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 OQS05161.1 - 0.0078 16.2 0.0 0.014 15.4 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 OQS05161.1 - 0.049 12.7 0.0 0.089 11.8 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 N6-adenineMlase PF10237.9 OQS05162.1 - 6.1e-42 143.2 1.8 1.4e-41 141.9 1.8 1.7 1 0 0 1 1 1 1 Probable N6-adenine methyltransferase adh_short PF00106.25 OQS05162.1 - 5.2e-36 123.9 1.9 1.1e-35 122.9 0.7 2.1 2 1 0 2 2 2 1 short chain dehydrogenase CRAL_TRIO PF00650.20 OQS05162.1 - 3.4e-35 121.1 0.1 9.8e-35 119.6 0.1 1.9 2 0 0 2 2 2 1 CRAL/TRIO domain adh_short_C2 PF13561.6 OQS05162.1 - 6.3e-28 97.9 0.4 1.2e-27 97.0 0.4 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OQS05162.1 - 6.9e-17 61.9 1.2 2.7e-16 60.0 1.2 1.9 1 1 0 1 1 1 1 KR domain SCP2 PF02036.17 OQS05162.1 - 1.2e-12 48.2 0.0 2.7e-12 47.0 0.0 1.6 1 0 0 1 1 1 1 SCP-2 sterol transfer family Epimerase PF01370.21 OQS05162.1 - 2.3e-06 27.2 0.3 1.3e-05 24.8 0.1 2.1 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family PH PF00169.29 OQS05162.1 - 3.5e-05 24.3 0.0 8e-05 23.1 0.0 1.7 1 0 0 1 1 1 1 PH domain CRAL_TRIO_2 PF13716.6 OQS05162.1 - 0.015 15.4 0.0 0.041 14.0 0.0 1.7 1 0 0 1 1 1 0 Divergent CRAL/TRIO domain GDP_Man_Dehyd PF16363.5 OQS05162.1 - 0.071 12.5 0.0 0.13 11.6 0.0 1.4 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase TMEM89 PF15098.6 OQS05162.1 - 0.096 12.9 0.0 0.27 11.4 0.0 1.7 1 0 0 1 1 1 0 TMEM89 protein family Alkyl_sulf_C PF14864.6 OQS05162.1 - 0.1 12.9 0.0 0.23 11.8 0.0 1.5 1 0 0 1 1 1 0 Alkyl sulfatase C-terminal Cons_hypoth95 PF03602.15 OQS05162.1 - 0.17 11.6 0.1 1.4 8.5 0.0 2.2 2 0 0 2 2 2 0 Conserved hypothetical protein 95 tRNA-synt_1b PF00579.25 OQS05164.1 - 5.9e-72 242.5 0.1 1.3e-71 241.3 0.1 1.5 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) TMC PF07810.13 OQS05164.1 - 3.5e-05 24.3 3.6 0.00014 22.4 3.6 2.2 1 0 0 1 1 1 1 TMC domain Anoctamin PF04547.12 OQS05164.1 - 0.00025 20.0 13.5 0.00025 20.0 13.5 2.3 1 1 0 2 2 2 1 Calcium-activated chloride channel Sipho_Gp157 PF05565.11 OQS05164.1 - 0.023 14.7 5.4 0.063 13.3 5.4 1.7 1 0 0 1 1 1 0 Siphovirus Gp157 SPT16 PF08644.11 OQS05164.1 - 0.51 10.5 2.9 2.1 8.5 2.9 2.1 1 0 0 1 1 1 0 FACT complex subunit (SPT16/CDC68) DUF3987 PF13148.6 OQS05164.1 - 2.2 7.2 5.3 3.5 6.5 5.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) IQ PF00612.27 OQS05165.1 - 4.7e-07 29.0 3.6 0.0064 16.2 0.7 3.0 2 0 0 2 2 2 2 IQ calmodulin-binding motif GAF_3 PF13492.6 OQS05165.1 - 0.00015 22.1 0.0 0.00031 21.1 0.0 1.5 1 0 0 1 1 1 1 GAF domain OPA3 PF07047.12 OQS05166.1 - 4.8e-31 107.1 0.1 7.7e-31 106.5 0.0 1.4 1 1 0 1 1 1 1 Optic atrophy 3 protein (OPA3) Cep57_MT_bd PF06657.13 OQS05166.1 - 0.0053 17.2 1.4 0.0053 17.2 1.4 1.9 2 0 0 2 2 2 1 Centrosome microtubule-binding domain of Cep57 PKcGMP_CC PF16808.5 OQS05166.1 - 0.019 14.8 0.2 0.11 12.4 0.3 2.2 2 0 0 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase ZapB PF06005.12 OQS05166.1 - 0.047 14.1 3.3 0.047 14.1 3.3 2.1 1 1 1 2 2 2 0 Cell division protein ZapB YabA PF06156.13 OQS05166.1 - 0.09 13.4 2.7 0.15 12.7 2.5 1.5 1 1 0 1 1 1 0 Initiation control protein YabA DivIC PF04977.15 OQS05166.1 - 0.15 11.9 8.0 2.2 8.1 0.2 2.4 1 1 1 2 2 2 0 Septum formation initiator ADIP PF11559.8 OQS05166.1 - 0.17 12.0 9.8 0.31 11.1 9.8 1.3 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding DUF812 PF05667.11 OQS05166.1 - 0.57 9.0 11.9 0.59 8.9 9.9 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF812) DUF4140 PF13600.6 OQS05166.1 - 1 9.8 5.5 26 5.4 5.5 2.4 1 1 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) BT1 PF03092.16 OQS05167.1 - 3.4e-18 65.2 12.6 1.7e-12 46.4 0.6 3.2 2 1 1 3 3 3 3 BT1 family MFS_1 PF07690.16 OQS05167.1 - 9.5e-10 37.9 36.1 1.8e-07 30.4 31.0 4.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF4506 PF14958.6 OQS05168.1 - 2.3e-08 33.7 1.5 7.2e-08 32.1 0.1 2.0 1 1 1 2 2 2 1 Domain of unknown function (DUF4506) RHIM PF12721.7 OQS05168.1 - 0.015 15.7 0.2 0.034 14.6 0.2 1.6 1 0 0 1 1 1 0 RIP homotypic interaction motif Flo11 PF10182.9 OQS05168.1 - 0.052 13.7 0.5 0.093 12.9 0.1 1.6 2 0 0 2 2 2 0 Flo11 domain ABC_tran_CTD PF16326.5 OQS05168.1 - 0.15 12.3 2.2 0.59 10.4 1.5 2.1 1 1 0 1 1 1 0 ABC transporter C-terminal domain Muted PF14942.6 OQS05168.1 - 0.61 10.4 6.0 0.18 12.2 2.1 1.9 2 0 0 2 2 2 0 Organelle biogenesis, Muted-like protein DUF3450 PF11932.8 OQS05170.1 - 0.005 16.2 12.1 0.005 16.2 12.1 4.4 1 1 3 4 4 4 1 Protein of unknown function (DUF3450) PE PF00934.20 OQS05170.1 - 0.018 15.3 8.2 0.071 13.4 1.0 2.8 2 0 0 2 2 2 0 PE family MtrB PF05440.12 OQS05170.1 - 0.14 12.6 2.6 2.5 8.6 0.1 3.2 3 1 1 4 4 4 0 Tetrahydromethanopterin S-methyltransferase subunit B GAS PF13851.6 OQS05170.1 - 1.4 8.3 69.9 0.39 10.0 33.9 3.8 1 1 3 4 4 4 0 Growth-arrest specific micro-tubule binding Golgin_A5 PF09787.9 OQS05170.1 - 5.4 6.4 69.7 4 6.8 12.2 3.7 1 1 3 4 4 4 0 Golgin subfamily A member 5 RCC1_2 PF13540.6 OQS05171.1 - 3.5e-22 77.7 16.7 1.4e-07 31.2 0.2 6.0 6 0 0 6 6 6 4 Regulator of chromosome condensation (RCC1) repeat RCC1 PF00415.18 OQS05171.1 - 5.5e-18 65.3 20.0 1.9e-07 31.6 0.0 6.5 8 1 0 8 8 8 4 Regulator of chromosome condensation (RCC1) repeat Mcl1_mid PF12341.8 OQS05171.1 - 0.019 14.3 0.1 0.29 10.4 0.0 2.6 3 0 0 3 3 3 0 Minichromosome loss protein, Mcl1, middle region MFS_1 PF07690.16 OQS05172.1 - 1.7e-50 172.0 52.9 7.6e-22 77.7 9.6 4.6 3 1 1 4 4 4 4 Major Facilitator Superfamily cNMP_binding PF00027.29 OQS05172.1 - 1.1e-14 54.3 0.3 7.9e-10 38.7 0.0 4.0 3 2 0 3 3 3 2 Cyclic nucleotide-binding domain Sugar_tr PF00083.24 OQS05172.1 - 5e-09 35.5 31.4 4.5e-07 29.1 2.2 4.9 4 1 1 5 5 5 3 Sugar (and other) transporter MFS_1_like PF12832.7 OQS05172.1 - 0.00074 18.5 25.1 2.2 7.0 13.6 5.5 3 2 1 4 4 4 3 MFS_1 like family RAMA PF18755.1 OQS05173.1 - 1.5e-08 35.0 0.0 3.6e-08 33.8 0.0 1.6 1 0 0 1 1 1 1 Restriction Enzyme Adenine Methylase Associated PHD PF00628.29 OQS05173.1 - 0.02 14.8 15.6 0.042 13.8 15.6 1.6 1 0 0 1 1 1 0 PHD-finger DUF1216 PF06746.11 OQS05173.1 - 0.081 12.9 8.3 3 7.9 0.1 4.1 4 0 0 4 4 4 0 Protein of unknown function (DUF1216) Rhodanese_C PF12368.8 OQS05173.1 - 1.8 9.0 12.0 5.4 7.5 12.0 1.8 1 0 0 1 1 1 0 Rhodanase C-terminal Prok-RING_1 PF14446.6 OQS05173.1 - 3.7 7.6 13.3 8 6.5 13.3 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 zf-RING_2 PF13639.6 OQS05173.1 - 4.7 7.6 16.9 11 6.5 16.9 1.7 1 0 0 1 1 1 0 Ring finger domain ddrB-ParB PF18763.1 OQS05174.1 - 0.067 13.3 0.6 0.18 11.9 0.1 1.9 2 0 0 2 2 2 0 ddrB-like ParB superfamily domain DASH_Dad3 PF08656.10 OQS05174.1 - 1.3 9.2 0.0 1.3 9.2 0.0 3.7 4 1 0 4 4 4 0 DASH complex subunit Dad3 UBA PF00627.31 OQS05175.1 - 7.7e-05 22.5 0.0 0.00018 21.3 0.0 1.6 1 0 0 1 1 1 1 UBA/TS-N domain HATPase_c_3 PF13589.6 OQS05175.1 - 0.00076 19.3 0.1 0.61 9.9 0.0 3.1 2 1 0 2 2 2 2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF3402 PF11882.8 OQS05176.1 - 6e-35 121.2 5.1 2.5e-27 96.1 1.2 2.3 1 1 1 2 2 2 2 Domain of unknown function (DUF3402) HAT_KAT11 PF08214.11 OQS05177.1 - 2.6e-25 89.5 0.3 7.4e-25 88.0 0.3 1.7 1 1 0 1 1 1 1 Histone acetylation protein Bromodomain PF00439.25 OQS05177.1 - 4.6e-16 58.7 0.0 9e-16 57.7 0.0 1.5 1 0 0 1 1 1 1 Bromodomain PHD PF00628.29 OQS05177.1 - 1.4e-06 28.1 1.8 1.4e-06 28.1 1.8 4.2 5 0 0 5 5 5 2 PHD-finger PHD_2 PF13831.6 OQS05177.1 - 0.0063 16.0 1.3 0.0063 16.0 1.3 3.2 3 0 0 3 3 3 1 PHD-finger DUF3772 PF12607.8 OQS05177.1 - 0.045 13.5 0.1 0.15 11.9 0.1 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3772) TAP42 PF04177.12 OQS05178.1 - 1.2e-58 198.8 14.5 1.4e-58 198.5 14.5 1.0 1 0 0 1 1 1 1 TAP42-like family zf-U1 PF06220.12 OQS05179.1 - 1e-19 70.0 6.3 1.6e-19 69.4 6.3 1.3 1 0 0 1 1 1 1 U1 zinc finger CLIP1_ZNF PF16641.5 OQS05179.1 - 0.034 14.0 1.5 0.047 13.6 1.5 1.2 1 0 0 1 1 1 0 CLIP1 zinc knuckle Med30 PF11315.8 OQS05180.1 - 6.6e-05 23.1 1.6 0.23 11.7 0.8 2.5 2 0 0 2 2 2 2 Mediator complex subunit 30 Syntaxin-6_N PF09177.11 OQS05180.1 - 0.004 17.7 12.6 0.0048 17.4 5.0 3.2 2 2 0 2 2 2 1 Syntaxin 6, N-terminal AKNA PF12443.8 OQS05180.1 - 0.084 13.5 0.1 0.084 13.5 0.1 3.1 2 1 1 3 3 3 0 AT-hook-containing transcription factor FapA PF03961.13 OQS05180.1 - 1.3 7.5 12.9 0.11 11.1 6.8 1.9 2 0 0 2 2 2 0 Flagellar Assembly Protein A Syntaxin_2 PF14523.6 OQS05180.1 - 4.4 7.7 12.5 2.7 8.4 4.6 2.4 2 0 0 2 2 2 0 Syntaxin-like protein Uso1_p115_C PF04871.13 OQS05180.1 - 8.8 6.7 14.9 0.81 10.1 7.7 2.4 2 0 0 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region UVR PF02151.19 OQS05181.1 - 0.05 13.4 0.3 3.6 7.5 0.1 2.4 2 0 0 2 2 2 0 UvrB/uvrC motif Ribosomal_L24e PF01246.20 OQS05182.1 - 7.7e-33 112.5 4.7 1.5e-32 111.6 4.7 1.5 1 0 0 1 1 1 1 Ribosomal protein L24e DUF2175 PF09943.9 OQS05182.1 - 1.6 9.0 6.9 0.74 10.1 1.0 2.5 1 1 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2175) Ank_2 PF12796.7 OQS05183.1 - 2.4e-26 92.1 14.7 9.1e-11 42.2 0.2 3.6 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQS05183.1 - 1.7e-19 69.9 3.4 3.2e-06 27.6 0.0 5.0 1 1 5 6 6 6 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 OQS05183.1 - 1.6e-16 60.2 4.3 6.6e-05 23.1 0.0 5.4 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQS05183.1 - 1e-13 50.1 5.2 0.096 13.3 0.1 6.5 6 1 0 6 6 6 4 Ankyrin repeat Ank PF00023.30 OQS05183.1 - 3e-13 49.5 6.5 0.024 15.1 0.1 5.7 6 0 0 6 6 6 3 Ankyrin repeat Ribosomal_S25 PF03297.15 OQS05183.1 - 0.0062 16.7 1.0 0.019 15.2 1.0 1.8 1 0 0 1 1 1 1 S25 ribosomal protein UPF0240 PF06784.11 OQS05183.1 - 0.063 13.3 2.0 0.65 10.0 1.5 2.1 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0240) SPATA3 PF15662.5 OQS05183.1 - 0.74 10.4 4.1 1.3 9.7 4.1 1.2 1 0 0 1 1 1 0 Spermatogenesis-associated protein 3 family Ribosomal_L37ae PF01780.19 OQS05184.1 - 1.3e-40 137.3 7.1 1.5e-40 137.1 7.1 1.0 1 0 0 1 1 1 1 Ribosomal L37ae protein family Zn_Tnp_IS1595 PF12760.7 OQS05184.1 - 0.31 11.1 5.7 0.55 10.2 5.7 1.4 1 0 0 1 1 1 0 Transposase zinc-ribbon domain zf-BED PF02892.15 OQS05184.1 - 7.3 6.7 11.0 0.39 10.8 0.8 2.6 2 1 1 3 3 3 0 BED zinc finger DnaJ PF00226.31 OQS05185.1 - 5.9e-22 77.6 0.6 2.6e-21 75.5 0.0 2.4 2 0 0 2 2 2 1 DnaJ domain Death PF00531.22 OQS05185.1 - 0.004 17.3 0.0 0.0078 16.3 0.0 1.5 1 0 0 1 1 1 1 Death domain DUF3209 PF11483.8 OQS05185.1 - 0.13 12.7 1.9 11 6.5 0.4 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3209) OAD_gamma PF04277.13 OQS05185.1 - 1.8 9.2 7.8 12 6.6 0.7 2.6 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain GAF PF01590.26 OQS05186.1 - 0.00023 21.8 0.0 0.00068 20.3 0.0 1.8 1 1 0 1 1 1 1 GAF domain Guanylate_cyc PF00211.20 OQS05187.1 - 1.9e-21 76.6 0.5 1.8e-09 37.5 0.1 2.4 2 0 0 2 2 2 2 Adenylate and Guanylate cyclase catalytic domain PH PF00169.29 OQS05187.1 - 1.2e-07 32.1 0.0 4e-07 30.5 0.0 1.9 1 0 0 1 1 1 1 PH domain AAA_16 PF13191.6 OQS05187.1 - 1.9e-05 25.1 0.0 0.00016 22.1 0.0 2.4 1 1 0 1 1 1 1 AAA ATPase domain FYVE PF01363.21 OQS05187.1 - 0.00053 20.1 15.6 0.00072 19.6 11.1 2.7 2 0 0 2 2 2 1 FYVE zinc finger TsaE PF02367.17 OQS05187.1 - 0.067 13.2 0.0 0.22 11.5 0.0 1.8 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE C1_2 PF03107.16 OQS05187.1 - 1.5 9.2 7.5 6 7.3 7.5 2.2 1 0 0 1 1 1 0 C1 domain CSRNP_N PF16019.5 OQS05188.1 - 0.046 13.6 0.5 0.046 13.6 0.5 1.5 2 0 0 2 2 2 0 Cysteine/serine-rich nuclear protein N-terminus Thioredoxin_6 PF13848.6 OQS05188.1 - 0.082 12.8 0.0 0.2 11.5 0.0 1.7 1 0 0 1 1 1 0 Thioredoxin-like domain ATP_sub_h PF10775.9 OQS05188.1 - 0.097 12.7 0.0 0.57 10.2 0.0 2.1 2 0 0 2 2 2 0 ATP synthase complex subunit h GATase PF00117.28 OQS05189.1 - 5.6e-49 166.5 0.0 9.2e-49 165.8 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase class-I RCC1 PF00415.18 OQS05189.1 - 6.6e-45 151.5 23.8 8.3e-14 51.9 0.1 9.8 10 0 0 10 10 10 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 OQS05189.1 - 2.6e-29 100.4 32.6 1.3e-05 24.8 0.2 7.7 8 0 0 8 8 8 5 Regulator of chromosome condensation (RCC1) repeat EF-hand_1 PF00036.32 OQS05189.1 - 2.1e-08 33.1 12.6 4e-06 26.0 1.4 3.6 3 0 0 3 3 3 2 EF hand EF-hand_7 PF13499.6 OQS05189.1 - 4.1e-08 33.6 4.7 2e-06 28.1 1.9 3.6 2 1 0 2 2 2 1 EF-hand domain pair EF-hand_5 PF13202.6 OQS05189.1 - 1.4e-06 27.5 6.7 0.001 18.5 0.4 3.1 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 OQS05189.1 - 1.9e-05 24.2 11.5 0.0082 16.0 1.1 3.3 3 0 0 3 3 3 2 EF-hand domain EF-hand_8 PF13833.6 OQS05189.1 - 2e-05 24.3 4.4 0.00053 19.8 0.7 2.7 2 0 0 2 2 2 1 EF-hand domain pair F5_F8_type_C PF00754.25 OQS05189.1 - 2.8e-05 24.2 0.0 0.00013 22.0 0.0 2.0 1 1 0 1 1 1 1 F5/8 type C domain Peptidase_C26 PF07722.13 OQS05189.1 - 0.00032 20.5 0.2 0.0011 18.8 0.2 1.9 1 1 0 1 1 1 1 Peptidase C26 Hira PF07569.11 OQS05189.1 - 0.0061 16.3 0.1 11 5.7 0.0 3.6 3 0 0 3 3 3 1 TUP1-like enhancer of split EF-hand_10 PF14788.6 OQS05189.1 - 1.3 8.9 4.7 0.43 10.5 0.0 2.7 3 1 1 4 4 4 0 EF hand GAF_2 PF13185.6 OQS05190.1 - 2.9e-07 30.9 0.0 4.6e-07 30.2 0.0 1.3 1 0 0 1 1 1 1 GAF domain GAF PF01590.26 OQS05190.1 - 6.1e-05 23.7 0.1 0.00014 22.5 0.1 1.6 1 0 0 1 1 1 1 GAF domain FYVE PF01363.21 OQS05190.1 - 8.9e-05 22.6 17.2 0.00033 20.7 17.1 2.0 1 1 0 1 1 1 1 FYVE zinc finger GAF_3 PF13492.6 OQS05190.1 - 0.00072 19.9 0.1 0.0013 19.1 0.1 1.4 1 0 0 1 1 1 1 GAF domain C1_2 PF03107.16 OQS05190.1 - 0.077 13.3 7.8 0.17 12.2 7.8 1.6 1 0 0 1 1 1 0 C1 domain DZR PF12773.7 OQS05190.1 - 0.18 11.9 8.8 0.32 11.1 1.7 2.4 1 1 1 2 2 2 0 Double zinc ribbon FYVE_2 PF02318.16 OQS05190.1 - 0.19 12.0 12.9 0.043 14.0 9.1 1.8 2 0 0 2 2 2 0 FYVE-type zinc finger Rhodanese_C PF12368.8 OQS05190.1 - 1.3 9.4 9.9 3 8.3 9.9 1.6 1 0 0 1 1 1 0 Rhodanase C-terminal zf-B_box PF00643.24 OQS05190.1 - 7.7 6.8 10.8 1.4 9.1 5.2 2.6 1 1 1 2 2 2 0 B-box zinc finger zf-RING_2 PF13639.6 OQS05191.1 - 3.5e-12 46.5 5.3 3.5e-12 46.5 5.3 2.5 4 0 0 4 4 2 1 Ring finger domain zf-RING_11 PF17123.5 OQS05191.1 - 1.2e-09 37.7 2.5 4.4e-09 35.9 2.5 2.0 1 0 0 1 1 1 1 RING-like zinc finger zf-rbx1 PF12678.7 OQS05191.1 - 1.5e-08 34.8 5.9 1.5e-08 34.8 5.9 2.8 2 1 0 2 2 2 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 OQS05191.1 - 1.2e-07 31.5 5.1 3.3e-07 30.0 5.1 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OQS05191.1 - 1.4e-06 28.2 3.3 5.2e-06 26.4 3.3 2.1 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 OQS05191.1 - 2.6e-06 27.2 2.1 2.6e-06 27.2 2.1 2.5 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 OQS05191.1 - 5.8e-06 26.1 5.3 5.8e-06 26.1 5.3 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OQS05191.1 - 9.1e-06 25.5 4.1 9.1e-06 25.5 4.1 2.1 3 0 0 3 3 2 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 OQS05191.1 - 1.3e-05 25.2 5.1 8.6e-05 22.5 2.5 3.4 3 2 0 3 3 3 1 Anaphase-promoting complex subunit 11 RING-H2 finger PX PF00787.24 OQS05191.1 - 4.5e-05 23.4 1.4 0.00015 21.7 0.3 2.3 2 0 0 2 2 2 1 PX domain Prok-RING_4 PF14447.6 OQS05191.1 - 6.4e-05 22.7 3.4 9.5e-05 22.2 1.7 2.2 2 1 0 2 2 2 1 Prokaryotic RING finger family 4 Zn_ribbon_17 PF17120.5 OQS05191.1 - 0.00019 21.0 6.6 0.00046 19.8 5.0 2.4 2 0 0 2 2 2 1 Zinc-ribbon, C4HC2 type zf-C3H2C3 PF17122.5 OQS05191.1 - 0.00038 20.4 1.9 0.00038 20.4 1.9 2.8 3 0 0 3 3 2 1 Zinc-finger Prok-RING_1 PF14446.6 OQS05191.1 - 0.0027 17.6 3.6 0.082 12.8 0.8 2.6 2 0 0 2 2 2 1 Prokaryotic RING finger family 1 FANCL_C PF11793.8 OQS05191.1 - 0.0083 16.3 4.1 0.075 13.2 4.1 2.6 1 1 0 1 1 1 1 FANCL C-terminal domain zf-Nse PF11789.8 OQS05191.1 - 0.019 14.8 4.4 0.033 14.0 1.6 2.6 3 0 0 3 3 3 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_4 PF14570.6 OQS05191.1 - 0.056 13.2 2.5 0.17 11.7 2.5 1.9 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain PHD PF00628.29 OQS05191.1 - 0.76 9.7 9.2 0.076 12.9 3.2 2.5 3 1 0 3 3 3 0 PHD-finger GAF_2 PF13185.6 OQS05192.1 - 6.1e-09 36.3 0.0 8.8e-09 35.8 0.0 1.3 1 0 0 1 1 1 1 GAF domain GAF_3 PF13492.6 OQS05192.1 - 4.2e-08 33.6 0.1 6.7e-08 32.9 0.1 1.3 1 0 0 1 1 1 1 GAF domain GAF PF01590.26 OQS05192.1 - 5.9e-08 33.4 0.0 1.1e-07 32.6 0.0 1.3 1 0 0 1 1 1 1 GAF domain FYVE PF01363.21 OQS05192.1 - 2.7e-06 27.4 7.9 4.4e-06 26.7 7.9 1.3 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.16 OQS05192.1 - 6.4e-05 23.1 6.4 0.00012 22.3 6.4 1.4 1 0 0 1 1 1 1 FYVE-type zinc finger zf-RING_2 PF13639.6 OQS05193.1 - 6.5e-10 39.2 7.0 6.5e-10 39.2 7.0 2.3 2 0 0 2 2 2 1 Ring finger domain PX PF00787.24 OQS05193.1 - 2e-09 37.4 1.1 3.1e-09 36.8 1.1 1.3 1 0 0 1 1 1 1 PX domain zf-rbx1 PF12678.7 OQS05193.1 - 2.3e-08 34.2 6.9 2.3e-08 34.2 6.9 2.1 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-RING_11 PF17123.5 OQS05193.1 - 1.1e-07 31.5 5.6 1.9e-07 30.7 3.6 2.4 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 OQS05193.1 - 2.8e-07 30.3 6.1 2.8e-07 30.3 6.1 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 OQS05193.1 - 8.1e-07 28.8 7.2 2.2e-06 27.4 7.2 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OQS05193.1 - 7.6e-06 25.8 4.7 2e-05 24.4 4.7 1.8 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 OQS05193.1 - 4.3e-05 23.3 7.4 0.0001 22.1 7.4 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OQS05193.1 - 0.0016 18.4 1.8 0.0016 18.4 1.8 2.9 2 1 1 3 3 3 1 RING-type zinc-finger Prok-RING_4 PF14447.6 OQS05193.1 - 0.0023 17.7 4.8 0.0075 16.1 4.8 1.9 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 OQS05193.1 - 0.0066 16.5 4.5 0.0066 16.5 4.5 2.7 3 1 0 3 3 3 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.6 OQS05193.1 - 0.15 11.9 6.6 0.66 9.8 6.6 2.0 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain E1-E2_ATPase PF00122.20 OQS05194.1 - 7.2e-46 156.0 1.0 2.2e-45 154.4 0.0 2.4 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 OQS05194.1 - 5.3e-45 154.3 2.1 9.4e-45 153.5 2.1 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HMA PF00403.26 OQS05194.1 - 6e-22 77.9 7.1 1.5e-05 25.3 0.1 4.5 4 0 0 4 4 4 4 Heavy-metal-associated domain Hydrolase_3 PF08282.12 OQS05194.1 - 1.4e-05 24.9 2.5 0.0016 18.2 1.4 2.5 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 OQS05194.1 - 0.0045 17.1 0.1 0.12 12.4 0.0 2.3 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase HAD PF12710.7 OQS05194.1 - 0.008 16.6 0.0 0.017 15.5 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 OQS05194.1 - 0.031 14.4 0.1 0.34 11.0 0.0 2.8 3 0 0 3 3 3 0 Haloacid dehalogenase-like hydrolase DUF2040 PF09745.9 OQS05195.1 - 7.9e-34 116.3 15.2 7.9e-34 116.3 15.2 2.5 2 1 1 3 3 3 1 Coiled-coil domain-containing protein 55 (DUF2040) GAS PF13851.6 OQS05196.1 - 0.00019 20.9 22.2 0.00019 20.9 22.2 4.3 1 1 3 4 4 4 1 Growth-arrest specific micro-tubule binding Vip3A_N PF12495.8 OQS05196.1 - 0.18 11.7 2.2 0.33 10.8 0.7 2.1 2 0 0 2 2 2 0 Vegetative insecticide protein 3A N terminal SHIPPO-rpt PF07004.12 OQS05197.1 - 3.5e-06 27.6 3.3 0.88 10.6 0.0 3.9 3 0 0 3 3 3 3 Sperm-tail PG-rich repeat Gp_dh_C PF02800.20 OQS05198.1 - 3.5e-34 117.7 0.0 5.5e-34 117.0 0.0 1.3 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 OQS05198.1 - 3.4e-19 69.0 0.2 1.1e-18 67.4 0.1 2.0 2 0 0 2 2 2 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain NDUF_B7 PF05676.13 OQS05199.1 - 1.3e-24 85.7 4.3 1.6e-24 85.4 4.3 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) Cmc1 PF08583.10 OQS05199.1 - 0.0034 17.4 3.8 0.0044 17.0 3.8 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like Pet191_N PF10203.9 OQS05199.1 - 0.06 13.6 4.2 3.2 8.1 2.0 2.3 1 1 1 2 2 2 0 Cytochrome c oxidase assembly protein PET191 zf-B_box PF00643.24 OQS05200.1 - 2.7e-05 24.2 7.8 2.7e-05 24.2 7.8 2.0 2 0 0 2 2 2 1 B-box zinc finger DHHC PF01529.20 OQS05201.1 - 6e-22 78.2 10.7 6e-22 78.2 10.7 1.6 2 0 0 2 2 2 1 DHHC palmitoyltransferase OAD_gamma PF04277.13 OQS05201.1 - 0.4 11.3 2.3 0.97 10.1 2.3 1.6 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain Phage_holin_3_6 PF07332.11 OQS05201.1 - 1.1 9.3 4.7 7.9 6.6 1.5 2.3 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III DUSP PF06337.12 OQS05202.1 - 1e-26 93.4 0.1 2.7e-11 43.9 0.0 3.9 4 0 0 4 4 4 2 DUSP domain PX PF00787.24 OQS05202.1 - 5.7e-19 68.2 10.5 2.5e-09 37.1 0.1 3.3 4 0 0 4 4 4 2 PX domain IQ PF00612.27 OQS05202.1 - 3.2e-07 29.5 0.8 0.00096 18.7 0.1 7.5 8 0 0 8 8 8 4 IQ calmodulin-binding motif PseudoU_synth_1 PF01416.20 OQS05203.1 - 0.0024 18.3 0.0 3.3 8.2 0.0 2.9 2 1 0 2 2 2 2 tRNA pseudouridine synthase UvrB_inter PF17757.1 OQS05203.1 - 0.088 13.0 0.0 0.32 11.2 0.0 2.0 1 1 0 1 1 1 0 UvrB interaction domain Ribosomal_L14 PF00238.19 OQS05203.1 - 0.16 12.0 0.4 0.64 10.1 0.1 1.8 2 0 0 2 2 2 0 Ribosomal protein L14p/L23e VPS28 PF03997.12 OQS05204.1 - 0.015 15.0 1.2 0.02 14.5 1.2 1.2 1 0 0 1 1 1 0 VPS28 protein RTBV_P46 PF06216.11 OQS05204.1 - 0.019 13.9 0.7 0.018 14.0 0.7 1.1 1 0 0 1 1 1 0 Rice tungro bacilliform virus P46 protein GAS PF13851.6 OQS05204.1 - 0.14 11.5 10.1 0.21 10.9 10.1 1.3 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding PspB PF06667.12 OQS05204.1 - 0.58 10.3 3.6 0.37 10.9 0.5 2.1 2 1 0 2 2 2 0 Phage shock protein B FlgN PF05130.12 OQS05204.1 - 2 8.9 10.5 26 5.3 10.5 2.0 1 1 0 1 1 1 0 FlgN protein 2OG-FeII_Oxy_3 PF13640.6 OQS05205.1 - 3.5e-06 27.8 0.1 0.012 16.4 0.0 2.7 2 0 0 2 2 2 2 2OG-Fe(II) oxygenase superfamily ANAPC4 PF12896.7 OQS05206.1 - 6.7e-33 113.9 2.0 1.3e-32 113.0 2.0 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 4 Ank_2 PF12796.7 OQS05206.1 - 2.3e-15 56.9 0.3 6.7e-08 33.0 0.1 3.1 3 1 1 4 4 4 2 Ankyrin repeats (3 copies) ANAPC4_WD40 PF12894.7 OQS05206.1 - 2.6e-14 53.3 0.1 8.1e-14 51.7 0.1 1.9 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 4 WD40 domain Ank_4 PF13637.6 OQS05206.1 - 1.2e-07 32.1 0.1 1.3e-05 25.7 0.1 2.8 1 1 1 2 2 2 2 Ankyrin repeats (many copies) 2OG-FeII_Oxy_3 PF13640.6 OQS05206.1 - 1.5e-07 32.2 0.0 3.6e-07 31.0 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Ank_5 PF13857.6 OQS05206.1 - 9.7e-06 25.8 0.3 5.6e-05 23.3 0.0 2.5 2 1 1 3 3 3 1 Ankyrin repeats (many copies) Ank PF00023.30 OQS05206.1 - 2.1e-05 24.8 0.0 0.00022 21.5 0.0 2.9 3 0 0 3 3 2 1 Ankyrin repeat zf-C3HC4_3 PF13920.6 OQS05206.1 - 0.0086 15.9 11.4 0.023 14.6 11.4 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Ank_3 PF13606.6 OQS05206.1 - 0.016 15.7 0.6 24 5.9 0.2 3.5 3 0 0 3 3 3 0 Ankyrin repeat zf-RING_5 PF14634.6 OQS05206.1 - 0.081 12.9 12.7 0.25 11.3 12.7 1.9 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_4 PF14570.6 OQS05206.1 - 0.36 10.7 9.0 1 9.2 9.0 1.9 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Prok-RING_4 PF14447.6 OQS05206.1 - 0.4 10.6 14.1 1.1 9.2 14.1 1.8 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 OQS05206.1 - 4.8 7.6 13.6 13 6.2 13.6 1.8 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4_2 PF13923.6 OQS05206.1 - 8.3 6.3 16.9 10 6.1 15.3 2.1 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF2443 PF10398.9 OQS05207.1 - 0.012 15.7 0.2 0.16 12.0 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2443) Vps5 PF09325.10 OQS05207.1 - 0.15 11.6 8.6 0.24 10.9 7.6 1.7 1 1 1 2 2 2 0 Vps5 C terminal like APG6_N PF17675.1 OQS05207.1 - 0.22 12.1 11.3 0.17 12.4 2.3 2.2 2 0 0 2 2 2 0 Apg6 coiled-coil region Fzo_mitofusin PF04799.13 OQS05207.1 - 0.66 9.5 7.5 0.47 10.0 0.6 2.3 1 1 1 2 2 2 0 fzo-like conserved region DivIC PF04977.15 OQS05207.1 - 2.6 7.9 13.5 0.18 11.6 2.1 2.9 2 1 1 3 3 3 0 Septum formation initiator FlxA PF14282.6 OQS05207.1 - 4.8 7.2 8.7 12 6.0 7.9 2.0 2 1 0 2 2 2 0 FlxA-like protein Got1 PF04178.12 OQS05208.1 - 6.3e-28 97.5 18.9 1.2e-27 96.6 18.5 1.6 1 1 1 2 2 2 1 Got1/Sft2-like family NICE-1 PF15845.5 OQS05208.1 - 0.044 14.6 0.1 0.11 13.3 0.1 1.7 1 0 0 1 1 1 0 Cysteine-rich C-terminal 1 family Ank_2 PF12796.7 OQS05209.1 - 4.6e-21 75.2 3.0 1.1e-19 70.8 1.0 3.3 2 1 1 3 3 3 1 Ankyrin repeats (3 copies) Methyltransf_16 PF10294.9 OQS05209.1 - 2e-20 73.3 0.3 1.3e-11 44.5 0.2 2.4 2 0 0 2 2 2 2 Lysine methyltransferase Ank_4 PF13637.6 OQS05209.1 - 4.4e-20 71.8 0.9 1e-07 32.3 0.1 3.9 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 OQS05209.1 - 2.7e-16 59.2 3.5 2.7e-06 27.5 0.0 5.3 5 0 0 5 5 5 2 Ankyrin repeat Ank_5 PF13857.6 OQS05209.1 - 4.6e-15 55.5 0.5 1.2e-05 25.4 0.0 3.8 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQS05209.1 - 7.4e-15 53.6 0.8 1.7e-05 24.8 0.0 4.5 4 0 0 4 4 4 2 Ankyrin repeat zf-MYND PF01753.18 OQS05209.1 - 1.5e-09 37.8 13.5 3.5e-09 36.6 13.5 1.7 1 0 0 1 1 1 1 MYND finger MTS PF05175.14 OQS05209.1 - 0.0014 18.2 0.2 0.083 12.4 0.0 3.0 3 0 0 3 3 3 1 Methyltransferase small domain Methyltransf_12 PF08242.12 OQS05209.1 - 0.0025 18.5 0.1 5.2 7.9 0.0 2.8 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_23 PF13489.6 OQS05209.1 - 0.0049 16.7 0.0 0.015 15.1 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.16 OQS05209.1 - 0.0067 16.2 0.0 0.013 15.2 0.0 1.4 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_11 PF08241.12 OQS05209.1 - 0.035 14.7 0.3 1.8 9.3 0.0 3.4 3 1 1 4 4 4 0 Methyltransferase domain DUF1871 PF08958.10 OQS05209.1 - 0.16 12.4 1.0 1.8 8.9 0.0 3.0 3 1 1 4 4 3 0 Domain of unknown function (DUF1871) zf-C6H2 PF15801.5 OQS05209.1 - 1 9.7 11.2 3.1 8.2 11.2 2.0 1 1 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding Translin PF01997.16 OQS05210.1 - 2.8e-27 96.0 2.3 2.6e-26 92.9 2.3 2.0 1 1 0 1 1 1 1 Translin family FliS PF02561.14 OQS05210.1 - 0.19 12.0 1.4 0.48 10.7 0.3 2.1 2 1 0 2 2 2 0 Flagellar protein FliS IRK_C PF17655.1 OQS05211.1 - 8.6e-22 77.6 1.1 1.3e-10 41.1 0.2 2.1 2 0 0 2 2 2 2 Inward rectifier potassium channel C-terminal domain IRK PF01007.20 OQS05211.1 - 3.6e-11 43.0 6.6 1.5e-07 31.3 0.3 2.5 1 1 1 2 2 2 2 Inward rectifier potassium channel transmembrane domain Ion_trans_2 PF07885.16 OQS05211.1 - 0.02 14.9 9.6 0.04 13.9 9.6 1.5 1 0 0 1 1 1 0 Ion channel SNF2_N PF00176.23 OQS05212.1 - 6.3e-72 242.2 0.5 1.8e-71 240.7 0.5 1.7 1 1 0 1 1 1 1 SNF2 family N-terminal domain SLIDE PF09111.10 OQS05212.1 - 2.9e-39 133.6 0.5 2.9e-39 133.6 0.5 3.1 3 0 0 3 3 3 1 SLIDE Helicase_C PF00271.31 OQS05212.1 - 3.8e-19 69.1 0.0 1.5e-18 67.1 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 OQS05212.1 - 4.2e-06 26.9 0.0 4.2e-06 26.9 0.0 3.6 4 1 0 4 4 4 1 Type III restriction enzyme, res subunit HAND PF09110.11 OQS05212.1 - 6.7e-06 26.8 13.7 6.7e-06 26.8 13.7 3.9 3 1 1 4 4 4 1 HAND DUF896 PF05979.12 OQS05212.1 - 0.005 16.7 7.2 0.005 16.7 7.2 3.2 3 0 0 3 3 3 1 Bacterial protein of unknown function (DUF896) Myb_DNA-binding PF00249.31 OQS05212.1 - 0.012 15.8 0.1 0.068 13.4 0.0 2.4 3 0 0 3 3 3 0 Myb-like DNA-binding domain MobB PF03205.14 OQS05212.1 - 0.037 13.9 0.1 0.15 12.0 0.0 2.0 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B bZIP_1 PF00170.21 OQS05214.1 - 3.2 7.9 13.6 9.3 6.4 0.9 2.6 1 1 1 2 2 2 0 bZIP transcription factor DOT1 PF08123.13 OQS05215.1 - 5.5e-24 84.8 0.0 9e-24 84.1 0.0 1.3 1 0 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_31 PF13847.6 OQS05215.1 - 0.012 15.5 0.4 0.04 13.7 0.4 1.8 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_4 PF02390.17 OQS05215.1 - 0.012 15.1 0.0 0.026 14.0 0.0 1.6 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_25 PF13649.6 OQS05215.1 - 0.071 13.8 0.0 0.17 12.6 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain EF-hand_7 PF13499.6 OQS05216.1 - 0.0076 16.7 0.1 0.02 15.4 0.1 1.7 1 0 0 1 1 1 1 EF-hand domain pair Ribosomal_S14 PF00253.21 OQS05216.1 - 0.035 13.9 0.4 0.072 12.9 0.4 1.5 1 0 0 1 1 1 0 Ribosomal protein S14p/S29e BTB PF00651.31 OQS05217.1 - 3.2e-22 78.8 0.0 5.4e-22 78.1 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain BACK PF07707.15 OQS05217.1 - 6.2e-09 35.9 0.8 3.3e-08 33.6 0.8 2.1 1 1 0 1 1 1 1 BTB And C-terminal Kelch UPF0242 PF06785.11 OQS05218.1 - 0.00032 20.9 6.3 0.033 14.3 1.3 2.3 2 0 0 2 2 2 2 Uncharacterised protein family (UPF0242) N-terminus DUF4618 PF15397.6 OQS05218.1 - 0.0026 17.2 7.2 0.13 11.7 1.7 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF4618) TolA_bind_tri PF16331.5 OQS05218.1 - 0.13 12.4 5.9 2.2 8.4 0.7 2.6 2 0 0 2 2 2 0 TolA binding protein trimerisation DUF1843 PF08898.10 OQS05218.1 - 0.17 12.4 2.0 1.7 9.2 0.0 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF1843) HECA PF15353.6 OQS05218.1 - 0.26 11.5 1.9 12 6.3 0.3 2.6 2 0 0 2 2 2 0 Headcase protein family homologue bZIP_2 PF07716.15 OQS05218.1 - 0.55 10.4 13.9 0.81 9.8 4.6 2.6 2 0 0 2 2 2 0 Basic region leucine zipper DivIC PF04977.15 OQS05218.1 - 0.91 9.3 7.1 1.7 8.5 1.8 2.5 2 0 0 2 2 2 0 Septum formation initiator kleA_kleC PF17383.2 OQS05218.1 - 1.1 9.6 6.8 2.1 8.8 0.6 2.4 2 0 0 2 2 2 0 Uncharacterized KorC regulated protein A TMF_TATA_bd PF12325.8 OQS05218.1 - 2.8 8.2 9.9 1.4 9.2 1.5 2.5 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding Chibby PF14645.6 OQS05218.1 - 3.1 8.3 6.3 1.4 9.3 0.8 2.3 2 0 0 2 2 2 0 Chibby family DUF4140 PF13600.6 OQS05218.1 - 3.3 8.2 6.0 9 6.8 0.6 2.3 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) GvpL_GvpF PF06386.11 OQS05218.1 - 4.6 7.1 7.1 0.6 10.0 0.6 2.1 2 0 0 2 2 2 0 Gas vesicle synthesis protein GvpL/GvpF PHO4 PF01384.20 OQS05219.1 - 6 5.8 11.3 14 4.6 0.1 2.5 1 1 1 2 2 2 0 Phosphate transporter family TAF6_C PF07571.13 OQS05221.1 - 5.8e-29 100.3 0.0 1.2e-28 99.3 0.0 1.6 1 0 0 1 1 1 1 TAF6 C-terminal HEAT repeat domain TAF PF02969.17 OQS05221.1 - 2.1e-22 79.1 0.1 3.8e-22 78.2 0.1 1.4 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) Histone PF00125.24 OQS05221.1 - 0.032 14.6 0.2 0.055 13.8 0.2 1.3 1 0 0 1 1 1 0 Core histone H2A/H2B/H3/H4 Mob_Pre PF01076.19 OQS05221.1 - 0.18 11.6 0.1 0.69 9.7 0.0 1.9 2 0 0 2 2 2 0 Plasmid recombination enzyme Med18 PF09637.10 OQS05222.1 - 1.8e-08 34.6 0.0 2.1e-07 31.0 0.0 2.0 1 1 0 1 1 1 1 Med18 protein Metallophos PF00149.28 OQS05223.1 - 2.9e-11 44.3 0.0 8.2e-11 42.8 0.0 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 OQS05223.1 - 0.00035 20.8 0.1 0.085 13.0 0.1 2.2 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain VPS9 PF02204.18 OQS05224.1 - 2.8e-26 91.8 0.1 8.8e-26 90.1 0.0 1.9 2 0 0 2 2 2 1 Vacuolar sorting protein 9 (VPS9) domain FSH1 PF03959.13 OQS05225.1 - 2.5e-29 102.5 0.0 2.9e-29 102.3 0.0 1.1 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_2 PF02230.16 OQS05225.1 - 0.00054 19.8 0.0 0.00077 19.3 0.0 1.3 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase TPR_1 PF00515.28 OQS05226.1 - 0.002 17.9 0.0 0.057 13.3 0.1 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.17 OQS05226.1 - 0.0039 17.2 2.9 0.0041 17.1 0.1 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 OQS05226.1 - 0.0042 17.1 2.1 2.2 8.4 0.2 2.9 2 1 1 3 3 3 2 Fis1 C-terminal tetratricopeptide repeat AhpC-TSA PF00578.21 OQS05227.1 - 1.1e-23 83.5 0.0 1.4e-23 83.1 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 OQS05227.1 - 4.3e-10 39.5 0.0 5.8e-10 39.1 0.0 1.2 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.9 OQS05227.1 - 9.5e-09 35.0 0.0 1.5e-08 34.3 0.0 1.4 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin Ank_2 PF12796.7 OQS05229.1 - 3.2e-25 88.5 12.5 8.9e-07 29.4 0.3 4.4 2 1 3 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQS05229.1 - 2.6e-18 66.1 12.1 0.00035 21.1 0.0 7.1 3 2 5 8 8 8 7 Ankyrin repeats (many copies) Ank_5 PF13857.6 OQS05229.1 - 4.1e-14 52.4 10.4 0.032 14.5 0.0 7.6 3 1 5 8 8 8 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQS05229.1 - 2.2e-11 42.9 2.0 1 10.1 0.0 9.0 9 1 1 10 10 10 1 Ankyrin repeat Ank PF00023.30 OQS05229.1 - 4.6e-05 23.7 1.2 23 5.6 0.0 6.0 3 3 1 4 4 4 1 Ankyrin repeat Methyltransf_32 PF13679.6 OQS05229.1 - 0.0002 21.4 0.2 1.1 9.2 0.0 4.0 1 1 3 4 4 4 1 Methyltransferase domain SBD_N PF07005.11 OQS05229.1 - 0.035 13.8 0.0 0.79 9.4 0.0 2.2 1 1 1 2 2 2 0 Sugar-binding N-terminal domain IBP39 PF11422.8 OQS05230.1 - 0.047 13.5 0.0 0.14 11.9 0.0 1.8 1 0 0 1 1 1 0 Initiator binding protein 39 kDa Fe-S_biosyn PF01521.20 OQS05231.1 - 5.7e-17 61.9 0.0 6.5e-17 61.7 0.0 1.0 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis DUF2326 PF10088.9 OQS05231.1 - 0.12 12.1 0.0 0.16 11.7 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein conserved in bacteria (DUF2326) zf-HIT PF04438.16 OQS05232.1 - 0.048 13.6 7.7 0.87 9.5 1.2 2.2 2 0 0 2 2 2 0 HIT zinc finger Zn_ribbon_SprT PF17283.2 OQS05232.1 - 0.067 13.1 0.6 16 5.5 0.1 2.6 2 0 0 2 2 2 0 SprT-like zinc ribbon domain zf-Mss51 PF13824.6 OQS05232.1 - 0.14 12.3 2.2 5 7.3 0.7 2.6 2 0 0 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 zf-CCHC_2 PF13696.6 OQS05232.1 - 2.4 8.1 8.3 11 5.9 1.3 2.4 2 0 0 2 2 2 0 Zinc knuckle zf-RING_2 PF13639.6 OQS05233.1 - 5.2e-24 84.3 26.1 1.3e-12 47.9 5.5 2.9 3 0 0 3 3 3 2 Ring finger domain zf-C3HC4_2 PF13923.6 OQS05233.1 - 3.5e-19 68.4 21.3 1.7e-09 37.4 7.2 2.5 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 OQS05233.1 - 3.5e-18 65.6 22.3 1.3e-08 35.0 7.1 3.3 2 1 0 2 2 2 2 RING-H2 zinc finger domain zf-C3HC4_3 PF13920.6 OQS05233.1 - 1.3e-15 56.9 14.3 1.1e-08 34.8 3.8 2.5 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 OQS05233.1 - 1.4e-14 53.5 16.5 2.1e-08 33.8 3.3 2.7 2 0 0 2 2 2 2 RING-like zinc finger zf-C3HC4 PF00097.25 OQS05233.1 - 2.6e-14 52.8 19.3 6.2e-07 29.2 6.0 2.7 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OQS05233.1 - 4.7e-14 52.1 14.6 6.1e-08 32.6 2.4 2.5 2 0 0 2 2 2 2 RING-type zinc-finger zf-ANAPC11 PF12861.7 OQS05233.1 - 3.3e-10 39.9 11.3 4.3e-06 26.7 0.7 3.0 3 0 0 3 3 3 2 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.6 OQS05233.1 - 4.3e-10 39.4 17.1 1e-05 25.4 4.9 2.5 2 0 0 2 2 2 2 zinc-RING finger domain Prok-RING_4 PF14447.6 OQS05233.1 - 5.4e-10 39.0 15.6 1.5e-06 28.0 3.9 2.5 2 0 0 2 2 2 2 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 OQS05233.1 - 1.1e-07 31.9 19.6 3.4e-05 23.9 3.3 3.0 3 0 0 3 3 2 2 zinc finger of C3HC4-type, RING Zn_ribbon_17 PF17120.5 OQS05233.1 - 1.2e-06 28.0 18.2 0.0024 17.5 4.2 3.0 3 0 0 3 3 3 2 Zinc-ribbon, C4HC2 type zf-RING_10 PF16685.5 OQS05233.1 - 0.00095 19.3 10.4 0.11 12.7 1.5 2.4 2 0 0 2 2 2 2 zinc RING finger of MSL2 FANCL_C PF11793.8 OQS05233.1 - 0.0047 17.1 15.8 0.037 14.2 2.9 3.4 2 1 0 2 2 2 1 FANCL C-terminal domain Vps39_2 PF10367.9 OQS05233.1 - 0.0066 16.9 10.8 0.86 10.1 0.1 4.0 4 0 0 4 4 4 2 Vacuolar sorting protein 39 domain 2 zf-C3H2C3 PF17122.5 OQS05233.1 - 0.011 15.7 10.4 0.74 9.9 0.7 3.2 2 1 0 2 2 2 0 Zinc-finger zf-RING_6 PF14835.6 OQS05233.1 - 0.079 12.8 13.3 0.35 10.8 1.5 3.5 3 0 0 3 3 3 0 zf-RING of BARD1-type protein DUF983 PF06170.12 OQS05233.1 - 0.086 13.3 3.0 7.8 7.0 0.0 3.4 4 0 0 4 4 3 0 Protein of unknown function (DUF983) RINGv PF12906.7 OQS05233.1 - 0.12 12.5 19.2 1.3 9.2 5.5 2.8 2 0 0 2 2 2 0 RING-variant domain Zn-C2H2_12 PF18112.1 OQS05233.1 - 0.13 12.7 2.5 5.2 7.6 0.1 3.1 3 0 0 3 3 2 0 Autophagy receptor zinc finger-C2H2 domain zf-RING_4 PF14570.6 OQS05233.1 - 0.32 10.8 15.0 1.7 8.5 3.1 2.9 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain Rtf2 PF04641.12 OQS05233.1 - 0.83 9.0 5.5 15 4.8 0.1 2.9 2 1 1 3 3 3 0 Rtf2 RING-finger Tmpp129 PF10272.9 OQS05233.1 - 1.1 8.5 18.3 2.8 7.2 5.1 3.0 2 2 1 3 3 3 0 Putative transmembrane protein precursor Atracotoxin PF05353.11 OQS05233.1 - 1.3 9.2 6.5 3 8.0 0.3 2.9 3 0 0 3 3 2 0 Delta Atracotoxin Prok-RING_1 PF14446.6 OQS05233.1 - 2.7 8.0 16.6 0.59 10.1 1.3 4.2 3 1 1 4 4 4 0 Prokaryotic RING finger family 1 zf-Nse PF11789.8 OQS05233.1 - 6.1 6.7 11.5 2.4 8.0 1.1 2.6 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit tRNA-synt_1c PF00749.21 OQS05234.1 - 3.9e-97 324.9 0.0 1.3e-96 323.2 0.0 1.9 2 0 0 2 2 2 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.18 OQS05234.1 - 1.9e-39 135.3 0.0 3.9e-39 134.3 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain FYVE PF01363.21 OQS05235.1 - 3.5e-05 23.9 4.4 4.5e-05 23.5 4.4 1.3 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.16 OQS05235.1 - 0.026 14.7 6.8 0.039 14.2 6.8 1.2 1 0 0 1 1 1 0 FYVE-type zinc finger Cytochrome_CBB3 PF13442.6 OQS05235.1 - 0.12 12.7 0.2 0.44 10.9 0.2 2.1 2 0 0 2 2 2 0 Cytochrome C oxidase, cbb3-type, subunit III C1_1 PF00130.22 OQS05235.1 - 0.54 10.2 9.0 0.94 9.4 9.0 1.4 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-RRN7 PF11781.8 OQS05235.1 - 0.57 9.9 4.9 1.2 8.9 0.2 2.6 2 0 0 2 2 2 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 WD40 PF00400.32 OQS05236.1 - 2.2e-26 91.6 15.5 3.5e-05 24.5 0.2 7.5 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OQS05236.1 - 4e-12 46.3 0.2 0.25 11.6 0.0 6.1 2 1 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain TPR_1 PF00515.28 OQS05236.1 - 5.1e-10 38.7 1.9 9.3e-06 25.2 0.0 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.6 OQS05236.1 - 1.6e-09 37.3 1.4 5.1e-09 35.7 0.7 2.1 1 1 1 2 2 2 1 TPR repeat TPR_2 PF07719.17 OQS05236.1 - 1.6e-09 37.1 1.6 4.9e-05 23.1 0.0 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 OQS05236.1 - 1e-07 31.6 1.3 0.00062 19.8 0.0 3.0 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_9 PF13371.6 OQS05236.1 - 3.9e-07 30.1 0.9 1.1e-06 28.7 0.9 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat VID27 PF08553.10 OQS05236.1 - 1.2e-05 24.5 0.0 0.0055 15.8 0.0 2.8 2 1 0 2 2 2 2 VID27 C-terminal WD40-like domain TPR_17 PF13431.6 OQS05236.1 - 3e-05 24.1 0.1 0.00012 22.2 0.1 2.1 2 0 0 2 2 1 1 Tetratricopeptide repeat TPR_19 PF14559.6 OQS05236.1 - 0.00042 20.8 2.0 0.00087 19.7 2.0 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat eIF2A PF08662.11 OQS05236.1 - 0.00094 19.1 0.0 2.6 7.9 0.0 3.3 3 0 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 OQS05236.1 - 0.0041 16.1 0.6 3 6.7 0.0 4.0 3 1 1 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein TPR_16 PF13432.6 OQS05236.1 - 0.0059 17.2 0.6 0.12 13.0 0.5 2.3 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 OQS05236.1 - 0.02 15.7 5.7 0.45 11.5 0.0 3.7 2 1 1 3 3 3 0 Tetratricopeptide repeat Bacteriocin_II PF01721.18 OQS05236.1 - 0.057 13.5 0.3 4.2 7.6 0.1 2.5 2 0 0 2 2 2 0 Class II bacteriocin PQQ_3 PF13570.6 OQS05236.1 - 0.081 13.4 0.2 2.4 8.8 0.0 3.4 4 0 0 4 4 3 0 PQQ-like domain ATG16 PF08614.11 OQS05236.1 - 2.9 8.0 32.2 0.057 13.6 20.0 2.9 2 1 0 2 2 2 0 Autophagy protein 16 (ATG16) TMEM51 PF15345.6 OQS05236.1 - 4.5 7.1 7.4 8.7 6.1 7.4 1.4 1 0 0 1 1 1 0 Transmembrane protein 51 Clat_adaptor_s PF01217.20 OQS05237.1 - 5.5e-10 39.3 0.2 6.6e-10 39.1 0.2 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain PTCRA PF15028.6 OQS05237.1 - 0.012 15.2 0.0 0.029 14.1 0.0 1.6 1 1 1 2 2 2 0 Pre-T-cell antigen receptor NADH-u_ox-rdase PF10785.9 OQS05238.1 - 3.4e-08 34.0 0.0 4.5e-08 33.7 0.0 1.2 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit Abhydrolase_6 PF12697.7 OQS05239.1 - 1.2e-05 26.0 0.7 3e-05 24.7 0.7 1.7 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.13 OQS05239.1 - 0.013 15.2 0.0 0.034 13.9 0.0 1.7 1 0 0 1 1 1 0 PGAP1-like protein NEL PF14496.6 OQS05239.1 - 0.044 13.2 0.8 0.14 11.5 0.1 2.2 2 0 0 2 2 2 0 C-terminal novel E3 ligase, LRR-interacting Arm PF00514.23 OQS05239.1 - 0.099 12.7 0.7 7.1 6.8 0.1 3.0 2 0 0 2 2 2 0 Armadillo/beta-catenin-like repeat LCAT PF02450.15 OQS05239.1 - 0.13 11.4 0.0 0.32 10.1 0.0 1.6 2 0 0 2 2 2 0 Lecithin:cholesterol acyltransferase HEAT_2 PF13646.6 OQS05239.1 - 0.25 11.7 2.8 3 8.3 0.0 3.7 4 0 0 4 4 4 0 HEAT repeats NADH-u_ox-rdase PF10785.9 OQS05240.1 - 3.2e-18 66.2 0.1 3.6e-18 66.0 0.1 1.0 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit ATP19 PF11022.8 OQS05240.1 - 0.47 10.9 2.7 6.1 7.3 0.3 2.1 1 1 1 2 2 2 0 ATP synthase subunit K DUF1027 PF06265.11 OQS05241.1 - 0.1 12.6 0.0 0.16 12.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1027) Whirly PF08536.11 OQS05242.1 - 1.9e-15 56.9 0.0 2.5e-15 56.5 0.0 1.1 1 0 0 1 1 1 1 Whirly transcription factor CRAL_TRIO PF00650.20 OQS05244.1 - 4.5e-20 72.0 1.6 8.8e-20 71.0 1.6 1.4 1 0 0 1 1 1 1 CRAL/TRIO domain PX PF00787.24 OQS05244.1 - 2.1e-11 43.8 0.3 9.5e-11 41.7 0.0 2.2 2 1 1 3 3 3 1 PX domain CRAL_TRIO_2 PF13716.6 OQS05244.1 - 1.2e-05 25.5 1.7 2.9e-05 24.2 1.7 1.6 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain DUF4321 PF14209.6 OQS05244.1 - 0.42 10.5 2.1 0.84 9.5 2.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4321) cobW PF02492.19 OQS05245.1 - 1.8e-33 115.6 0.0 3e-33 114.9 0.0 1.4 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain zf-AN1 PF01428.16 OQS05245.1 - 2.5e-09 37.1 6.9 2.5e-09 37.1 6.9 3.2 2 1 0 2 2 1 1 AN1-like Zinc finger MeaB PF03308.16 OQS05245.1 - 0.00035 19.6 0.5 0.0011 18.0 0.5 1.7 1 1 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB MMR_HSR1 PF01926.23 OQS05245.1 - 0.0057 16.7 0.0 0.019 15.0 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase PknG_rubred PF16919.5 OQS05245.1 - 0.024 14.8 0.4 0.073 13.2 0.4 1.8 1 0 0 1 1 1 0 Protein kinase G rubredoxin domain AAA_5 PF07728.14 OQS05245.1 - 0.046 13.7 0.0 0.091 12.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) ATPase_2 PF01637.18 OQS05245.1 - 0.12 12.3 0.0 0.24 11.3 0.0 1.5 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_23 PF13476.6 OQS05245.1 - 0.14 12.6 0.1 0.38 11.2 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 OQS05245.1 - 0.15 12.5 0.0 0.3 11.4 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain AAA_18 PF13238.6 OQS05245.1 - 0.22 12.0 6.8 0.23 12.0 0.0 2.7 2 1 0 2 2 2 0 AAA domain Zip PF02535.22 OQS05245.1 - 1.6 7.9 13.3 2.7 7.1 13.3 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter FAM176 PF14851.6 OQS05245.1 - 7.9 6.1 6.0 27 4.4 6.0 1.9 1 1 0 1 1 1 0 FAM176 family RNA_pol PF00940.19 OQS05246.1 - 1.3e-152 508.4 0.0 5.4e-152 506.4 0.0 2.1 1 1 0 1 1 1 1 DNA-dependent RNA polymerase RPOL_N PF14700.6 OQS05246.1 - 5.3e-52 177.3 1.5 8.9e-52 176.5 0.0 2.1 3 0 0 3 3 3 1 DNA-directed RNA polymerase N-terminal Ank_5 PF13857.6 OQS05247.1 - 8.4e-15 54.7 0.3 0.0002 21.6 0.0 4.2 1 1 3 4 4 4 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 OQS05247.1 - 1.2e-14 54.6 3.6 4.3e-07 30.4 1.8 2.5 1 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQS05247.1 - 2.7e-12 46.9 1.7 7.6e-07 29.6 0.2 3.4 1 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQS05247.1 - 4.9e-08 32.6 0.1 0.99 10.2 0.0 4.0 4 0 0 4 4 4 3 Ankyrin repeat DUF5049 PF16468.5 OQS05247.1 - 3.1e-06 27.0 0.2 0.42 10.5 0.0 4.1 4 1 1 5 5 5 2 Domain of unknown function (DUF5049) Ank PF00023.30 OQS05247.1 - 0.00016 22.0 0.4 2.4 8.8 0.0 4.2 2 1 1 3 3 3 1 Ankyrin repeat Tom37 PF10568.9 OQS05247.1 - 0.035 14.4 0.2 15 6.0 0.1 2.8 1 1 1 2 2 2 0 Outer mitochondrial membrane transport complex protein Ribosomal_S17_N PF16205.5 OQS05248.1 - 8.2e-32 109.4 0.8 8.2e-32 109.4 0.8 1.7 2 0 0 2 2 2 1 Ribosomal_S17 N-terminal Ribosomal_S17 PF00366.20 OQS05248.1 - 3.6e-26 91.0 1.2 3.6e-26 91.0 1.2 1.8 2 0 0 2 2 2 1 Ribosomal protein S17 G-patch PF01585.23 OQS05250.1 - 1.3e-15 57.0 1.5 3.1e-15 55.8 1.5 1.7 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 OQS05250.1 - 8.4e-06 25.8 0.7 8.4e-06 25.8 0.7 2.7 3 0 0 3 3 3 1 G-patch domain DUF4604 PF15377.6 OQS05250.1 - 0.92 9.9 26.4 1.9 8.9 26.1 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4604) HECT PF00632.25 OQS05252.1 - 1.1e-60 205.8 0.0 2.5e-60 204.6 0.0 1.5 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) SPRY PF00622.28 OQS05252.1 - 1.4e-18 67.1 0.0 3.8e-18 65.7 0.0 1.8 1 0 0 1 1 1 1 SPRY domain Laminin_G_3 PF13385.6 OQS05252.1 - 1.2e-10 41.7 0.0 6.4e-10 39.4 0.0 2.2 2 0 0 2 2 2 1 Concanavalin A-like lectin/glucanases superfamily UBA PF00627.31 OQS05252.1 - 0.0032 17.4 0.0 0.0075 16.2 0.0 1.7 1 0 0 1 1 1 1 UBA/TS-N domain Laminin_G_2 PF02210.24 OQS05252.1 - 0.015 15.9 0.0 0.042 14.4 0.0 1.8 1 0 0 1 1 1 0 Laminin G domain BUD22 PF09073.10 OQS05252.1 - 3.6 6.8 6.8 5.5 6.2 6.8 1.1 1 0 0 1 1 1 0 BUD22 NOA36 PF06524.12 OQS05252.1 - 5.3 6.3 13.0 10 5.3 13.0 1.4 1 0 0 1 1 1 0 NOA36 protein DUF1664 PF07889.12 OQS05253.1 - 1.6 8.8 19.5 0.32 11.0 1.5 4.1 4 0 0 4 4 4 0 Protein of unknown function (DUF1664) GCV_T PF01571.21 OQS05254.1 - 2.2e-62 210.7 0.0 3e-62 210.3 0.0 1.2 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain DAO PF01266.24 OQS05254.1 - 3.8e-55 187.9 0.2 6.2e-55 187.2 0.2 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAO_M PF16350.5 OQS05254.1 - 7.9e-20 71.0 0.3 2.6e-19 69.3 0.3 2.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase central domain GCV_T_C PF08669.11 OQS05254.1 - 5.1e-15 55.2 0.0 1.7e-14 53.5 0.0 1.9 2 0 0 2 2 2 1 Glycine cleavage T-protein C-terminal barrel domain FAD_binding_2 PF00890.24 OQS05254.1 - 9.1e-07 28.3 1.3 3.9e-06 26.2 1.3 1.9 1 1 0 1 1 1 1 FAD binding domain SoxG PF04268.12 OQS05254.1 - 7.2e-05 23.0 0.0 0.00013 22.2 0.0 1.3 1 0 0 1 1 1 1 Sarcosine oxidase, gamma subunit family Thi4 PF01946.17 OQS05254.1 - 0.00063 19.1 0.3 0.0038 16.5 0.0 2.0 2 0 0 2 2 2 1 Thi4 family FAD_binding_3 PF01494.19 OQS05254.1 - 0.0091 15.3 0.2 0.019 14.2 0.2 1.5 2 0 0 2 2 2 1 FAD binding domain GIDA PF01134.22 OQS05254.1 - 0.014 14.6 2.1 0.5 9.4 0.5 2.2 2 0 0 2 2 2 0 Glucose inhibited division protein A Pyr_redox_2 PF07992.14 OQS05254.1 - 0.022 14.0 0.0 0.089 12.0 0.0 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.6 OQS05254.1 - 0.056 13.9 0.0 0.15 12.5 0.0 1.7 1 0 0 1 1 1 0 Putative NAD(P)-binding NAD_binding_8 PF13450.6 OQS05254.1 - 0.073 13.3 0.3 0.4 11.0 0.3 2.3 1 1 1 2 2 2 0 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 OQS05254.1 - 0.18 11.1 0.8 0.75 9.1 0.8 1.9 1 1 0 1 1 1 0 FAD dependent oxidoreductase SmpB PF01668.18 OQS05256.1 - 1.3e-19 70.5 0.1 2.3e-19 69.7 0.1 1.4 1 0 0 1 1 1 1 SmpB protein VPS9 PF02204.18 OQS05256.1 - 8.7e-17 61.2 0.0 2e-16 60.1 0.0 1.7 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain PX PF00787.24 OQS05256.1 - 0.00017 21.6 0.3 0.00051 20.0 0.0 1.9 2 0 0 2 2 2 1 PX domain Ninjurin PF04923.12 OQS05257.1 - 0.052 13.5 0.6 0.15 12.0 0.2 1.9 1 1 1 2 2 2 0 Ninjurin IQ PF00612.27 OQS05260.1 - 0.0012 18.4 2.2 0.0035 17.0 2.2 1.8 1 0 0 1 1 1 1 IQ calmodulin-binding motif PH PF00169.29 OQS05260.1 - 0.009 16.5 0.1 0.017 15.6 0.1 1.4 1 0 0 1 1 1 1 PH domain tRNA_synt_1c_R2 PF04557.15 OQS05262.1 - 3.5 8.6 11.6 0.34 11.9 4.0 2.1 2 0 0 2 2 2 0 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 2 MFS_1 PF07690.16 OQS05265.1 - 6.2e-07 28.7 21.6 7.3e-06 25.1 18.2 3.0 1 1 2 3 3 3 3 Major Facilitator Superfamily L51_S25_CI-B8 PF05047.16 OQS05266.1 - 6.1e-05 22.9 0.1 0.0001 22.2 0.1 1.4 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain SUI1 PF01253.22 OQS05267.1 - 5.3e-23 81.3 0.5 6.5e-23 81.1 0.5 1.1 1 0 0 1 1 1 1 Translation initiation factor SUI1 DUF2997 PF11211.8 OQS05267.1 - 0.027 14.3 0.0 0.045 13.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2997) Ank_2 PF12796.7 OQS05269.1 - 3.9e-14 53.0 2.8 1.6e-05 25.4 0.5 3.9 2 1 3 5 5 5 4 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OQS05269.1 - 5.1e-11 42.6 5.6 0.17 12.2 0.2 5.7 1 1 5 6 6 6 4 Ankyrin repeats (many copies) Ank_4 PF13637.6 OQS05269.1 - 1.3e-09 38.3 8.3 0.002 18.6 0.0 5.1 2 1 3 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQS05269.1 - 1.3e-07 31.3 1.1 18 6.3 0.0 6.4 6 0 0 6 6 6 2 Ankyrin repeat DUF249 PF03158.13 OQS05269.1 - 0.00019 21.2 0.6 0.046 13.4 0.3 3.1 1 1 1 3 3 3 1 Multigene family 530 protein Ank PF00023.30 OQS05269.1 - 0.1 13.1 1.4 1.1e+02 3.4 0.0 4.5 3 2 0 3 3 3 0 Ankyrin repeat Ank_2 PF12796.7 OQS05270.1 - 2.1e-106 348.7 56.3 1.9e-16 60.4 0.5 10.5 4 2 5 11 11 11 11 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQS05270.1 - 4.2e-76 250.4 26.4 1.2e-11 44.9 0.1 12.9 9 3 3 13 13 12 11 Ankyrin repeats (many copies) Ank PF00023.30 OQS05270.1 - 2.9e-60 198.2 47.8 0.00012 22.4 0.0 21.0 23 0 0 23 23 21 14 Ankyrin repeat Ank_3 PF13606.6 OQS05270.1 - 7.2e-60 191.9 35.7 0.0027 18.1 0.0 21.0 22 0 0 22 22 21 15 Ankyrin repeat Pkinase_Tyr PF07714.17 OQS05270.1 - 1.3e-55 188.5 0.0 1.9e-32 112.6 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Ank_5 PF13857.6 OQS05270.1 - 4.6e-55 182.9 42.0 1.5e-07 31.5 0.1 18.4 5 5 15 20 20 20 15 Ankyrin repeats (many copies) Pkinase PF00069.25 OQS05270.1 - 2e-52 178.2 0.0 2.9e-30 105.5 0.0 2.4 2 0 0 2 2 2 2 Protein kinase domain Kdo PF06293.14 OQS05270.1 - 0.016 14.6 0.7 1.2 8.5 0.0 2.4 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 OQS05270.1 - 0.017 14.4 0.1 0.86 8.9 0.0 2.4 2 0 0 2 2 2 0 Kinase-like F-box_5 PF18511.1 OQS05270.1 - 0.089 12.4 0.2 0.36 10.4 0.1 2.1 2 0 0 2 2 2 0 F-box Response_reg PF00072.24 OQS05270.1 - 0.11 12.6 0.1 3.9 7.7 0.0 3.1 3 0 0 3 3 3 0 Response regulator receiver domain Fip1 PF05182.13 OQS05271.1 - 1.1e-24 85.7 1.1 2.2e-24 84.7 1.1 1.5 1 0 0 1 1 1 1 Fip1 motif Ribosomal_S8 PF00410.19 OQS05272.1 - 7.5e-22 77.6 0.1 1.3e-21 76.9 0.1 1.4 1 1 0 1 1 1 1 Ribosomal protein S8 Diphthami_syn_2 PF01902.17 OQS05273.1 - 2.8e-45 154.5 0.1 9.9e-45 152.7 0.0 1.9 2 0 0 2 2 2 1 Diphthamide synthase Ribonuc_L-PSP PF01042.21 OQS05273.1 - 1.5e-29 102.4 0.3 1.4e-15 57.4 0.0 3.3 3 0 0 3 3 3 3 Endoribonuclease L-PSP Glucan_synthase PF02364.15 OQS05274.1 - 3.8e-183 610.8 22.3 2.2e-164 548.8 5.6 2.9 2 1 1 3 3 3 2 1,3-beta-glucan synthase component FKS1_dom1 PF14288.6 OQS05274.1 - 9.4e-23 81.0 0.3 4.9e-21 75.4 0.3 2.9 1 1 0 1 1 1 1 1,3-beta-glucan synthase subunit FKS1, domain-1 DUF1722 PF08349.11 OQS05274.1 - 0.034 14.4 0.3 0.1 12.9 0.3 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1722) Ribosomal_L21e PF01157.18 OQS05275.1 - 8.3e-45 150.8 8.2 8.3e-45 150.8 8.2 1.5 2 0 0 2 2 2 1 Ribosomal protein L21e zf-met PF12874.7 OQS05277.1 - 0.0015 18.8 1.5 0.0031 17.8 1.5 1.6 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 OQS05277.1 - 0.0064 16.8 2.3 0.012 15.9 2.3 1.5 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 OQS05277.1 - 0.011 16.0 0.4 0.024 15.0 0.4 1.5 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) Peripla_BP_2 PF01497.18 OQS05278.1 - 3.7e-05 23.4 0.0 6.6e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 Periplasmic binding protein FA_desaturase PF00487.24 OQS05279.1 - 4.2e-14 53.0 19.5 7.3e-14 52.2 19.5 1.3 1 0 0 1 1 1 1 Fatty acid desaturase DUF2616 PF11077.8 OQS05281.1 - 0.22 11.2 5.1 0.077 12.7 1.6 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2616) Mannosyl_trans3 PF11051.8 OQS05282.1 - 4e-29 101.8 0.1 5e-29 101.5 0.1 1.1 1 0 0 1 1 1 1 Mannosyltransferase putative DnaJ PF00226.31 OQS05283.1 - 1.5e-25 89.1 0.5 1.5e-25 89.1 0.5 2.2 3 0 0 3 3 3 1 DnaJ domain DUF1977 PF09320.11 OQS05283.1 - 6.5e-20 71.4 0.2 1.4e-19 70.3 0.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1977) Relaxase PF03432.14 OQS05283.1 - 0.057 13.0 0.5 0.15 11.6 0.5 1.7 1 0 0 1 1 1 0 Relaxase/Mobilisation nuclease domain MMR_HSR1 PF01926.23 OQS05284.1 - 6.3e-06 26.3 0.0 4.1e-05 23.6 0.0 2.4 2 0 0 2 2 2 1 50S ribosome-binding GTPase RHD3 PF05879.12 OQS05284.1 - 2.4e-05 22.7 0.0 2.4e-05 22.7 0.0 2.0 2 0 0 2 2 2 1 Root hair defective 3 GTP-binding protein (RHD3) GBP PF02263.19 OQS05284.1 - 7.6e-05 22.1 0.0 0.00033 20.0 0.0 2.1 2 0 0 2 2 2 1 Guanylate-binding protein, N-terminal domain Dynamin_N PF00350.23 OQS05284.1 - 0.00011 22.3 0.1 0.0021 18.2 0.1 2.7 1 1 1 2 2 2 1 Dynamin family FeoB_N PF02421.18 OQS05284.1 - 0.028 13.9 0.3 0.34 10.4 0.3 2.3 1 1 0 1 1 1 0 Ferrous iron transport protein B ABC_tran PF00005.27 OQS05284.1 - 0.17 12.4 0.7 7.5 7.1 0.0 2.7 2 0 0 2 2 2 0 ABC transporter Nucleoporin_FG PF13634.6 OQS05285.1 - 1.2e-18 67.7 22.0 7.8e-08 33.1 1.1 4.0 2 1 1 3 3 3 3 Nucleoporin FG repeat region M-factor PF03855.13 OQS05285.1 - 0.034 14.3 1.5 0.15 12.2 1.5 2.1 1 0 0 1 1 1 0 M-factor AMP-binding PF00501.28 OQS05286.1 - 1e-88 297.8 0.0 1.3e-88 297.4 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 OQS05286.1 - 0.047 14.7 0.0 0.14 13.2 0.0 1.8 1 1 0 1 1 1 0 AMP-binding enzyme C-terminal domain Borrelia_P83 PF05262.11 OQS05286.1 - 0.18 10.3 0.0 0.34 9.4 0.0 1.3 1 0 0 1 1 1 0 Borrelia P83/100 protein PX PF00787.24 OQS05287.1 - 1.3e-10 41.2 0.2 1.8e-10 40.8 0.2 1.2 1 0 0 1 1 1 1 PX domain Rib_recp_KP_reg PF05104.12 OQS05288.1 - 2.3 9.2 9.5 0.48 11.5 4.4 2.0 2 0 0 2 2 2 0 Ribosome receptor lysine/proline rich region adh_short PF00106.25 OQS05289.1 - 3.7e-15 55.9 0.0 4.3e-15 55.7 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OQS05289.1 - 2.7e-08 33.7 0.0 4e-08 33.1 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OQS05289.1 - 5e-06 26.5 0.0 6.9e-06 26.1 0.0 1.2 1 0 0 1 1 1 1 KR domain YjeF_N PF03853.15 OQS05289.1 - 0.0031 17.4 0.0 0.0035 17.2 0.0 1.1 1 0 0 1 1 1 1 YjeF-related protein N-terminus Pyr_redox_3 PF13738.6 OQS05289.1 - 0.086 12.1 0.0 0.1 11.8 0.0 1.1 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase ELO PF01151.18 OQS05290.1 - 1.1e-68 231.5 22.3 1.3e-68 231.2 22.3 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family PX PF00787.24 OQS05291.1 - 1.5e-10 41.1 0.5 3.1e-10 40.0 0.1 1.7 2 0 0 2 2 2 1 PX domain Pkinase PF00069.25 OQS05292.1 - 8.3e-45 153.2 0.0 2.1e-44 151.9 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQS05292.1 - 2.6e-44 151.4 0.0 5.4e-44 150.4 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase EphA2_TM PF14575.6 OQS05292.1 - 0.0024 18.7 0.0 0.0054 17.6 0.0 1.6 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain Protocadherin PF08374.11 OQS05292.1 - 0.013 15.5 0.0 0.024 14.6 0.0 1.4 1 0 0 1 1 1 0 Protocadherin APH PF01636.23 OQS05292.1 - 0.023 14.6 0.0 0.097 12.6 0.0 1.9 2 0 0 2 2 2 0 Phosphotransferase enzyme family TMEM154 PF15102.6 OQS05292.1 - 0.024 14.5 0.4 0.024 14.5 0.4 1.6 2 0 0 2 2 1 0 TMEM154 protein family Choline_kinase PF01633.20 OQS05292.1 - 0.029 13.9 0.1 3.9 7.0 0.0 2.3 2 0 0 2 2 2 0 Choline/ethanolamine kinase Crystall PF00030.19 OQS05292.1 - 0.042 14.0 0.1 0.11 12.8 0.1 1.7 1 0 0 1 1 1 0 Beta/Gamma crystallin RETICULATA-like PF11891.8 OQS05292.1 - 0.055 13.3 0.0 0.1 12.4 0.0 1.4 1 0 0 1 1 1 0 Protein RETICULATA-related TNFR_16_TM PF18422.1 OQS05292.1 - 0.062 13.3 1.6 0.12 12.3 1.6 1.5 1 0 0 1 1 1 0 Tumor necrosis factor receptor member 16 trans-membrane domain Pkinase_fungal PF17667.1 OQS05292.1 - 0.062 12.1 0.7 0.13 11.0 0.0 1.7 2 0 0 2 2 2 0 Fungal protein kinase Glycophorin_A PF01102.18 OQS05292.1 - 0.069 13.4 0.1 0.17 12.1 0.1 1.6 1 0 0 1 1 1 0 Glycophorin A Adeno_E3_CR2 PF02439.15 OQS05292.1 - 0.077 12.8 0.1 0.18 11.6 0.1 1.6 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Shisa PF13908.6 OQS05292.1 - 0.089 13.0 0.7 0.14 12.4 0.7 1.2 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator JCAD PF15351.6 OQS05292.1 - 0.1 10.4 0.8 0.14 9.9 0.8 1.1 1 0 0 1 1 1 0 Junctional protein associated with coronary artery disease DUF4307 PF14155.6 OQS05292.1 - 0.26 11.2 1.2 28 4.6 0.1 2.9 3 0 0 3 3 2 0 Domain of unknown function (DUF4307) Ank_4 PF13637.6 OQS05293.1 - 6.6e-06 26.6 0.0 0.00044 20.8 0.0 2.4 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 OQS05293.1 - 4.8e-05 23.9 0.0 0.051 14.2 0.0 2.3 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) HSP33 PF01430.19 OQS05293.1 - 0.0021 17.5 0.3 0.013 14.9 0.0 2.0 2 0 0 2 2 2 1 Hsp33 protein Ank_3 PF13606.6 OQS05293.1 - 0.011 16.2 0.0 65 4.6 0.0 3.4 3 0 0 3 3 3 0 Ankyrin repeat Ank_5 PF13857.6 OQS05293.1 - 0.19 12.1 0.0 35 4.9 0.0 3.1 3 0 0 3 3 3 0 Ankyrin repeats (many copies) ATG16 PF08614.11 OQS05294.1 - 0.00041 20.6 52.0 0.21 11.8 22.8 4.1 1 1 3 4 4 4 2 Autophagy protein 16 (ATG16) DUF4201 PF13870.6 OQS05294.1 - 0.00043 20.1 7.3 0.00043 20.1 7.3 4.6 1 1 4 5 5 5 2 Domain of unknown function (DUF4201) Fez1 PF06818.15 OQS05294.1 - 0.0062 17.0 46.7 0.62 10.5 5.0 4.0 1 1 1 2 2 2 1 Fez1 HMMR_N PF15905.5 OQS05294.1 - 0.97 8.8 49.1 0.044 13.2 3.5 3.1 1 1 2 3 3 3 0 Hyaluronan mediated motility receptor N-terminal CALCOCO1 PF07888.11 OQS05294.1 - 1.4 7.7 49.0 0.19 10.6 23.7 3.1 1 1 2 3 3 3 0 Calcium binding and coiled-coil domain (CALCOCO1) like GreA_GreB_N PF03449.15 OQS05294.1 - 6.8 6.9 11.0 1.5 9.0 1.4 4.1 4 0 0 4 4 4 0 Transcription elongation factor, N-terminal FPP PF05911.11 OQS05294.1 - 7.3 4.6 47.9 0.27 9.4 6.3 2.9 1 1 2 3 3 3 0 Filament-like plant protein, long coiled-coil Ank_2 PF12796.7 OQS05295.1 - 8.3e-22 77.6 4.4 3.8e-09 37.0 0.1 4.1 1 1 4 5 5 5 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQS05295.1 - 5.6e-17 61.9 7.1 9.9e-07 29.2 0.2 5.7 3 2 3 6 6 6 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 OQS05295.1 - 2.2e-13 50.1 3.9 0.011 16.1 0.0 6.4 2 1 4 6 6 6 5 Ankyrin repeats (many copies) DUF5049 PF16468.5 OQS05295.1 - 3.8e-09 36.3 2.9 1 9.3 0.0 5.6 1 1 4 5 5 5 3 Domain of unknown function (DUF5049) Ank_3 PF13606.6 OQS05295.1 - 1.6e-06 28.0 4.1 0.22 12.2 0.0 6.3 6 1 1 7 7 7 2 Ankyrin repeat PyrI PF01948.18 OQS05295.1 - 0.05 13.9 0.0 0.9 9.8 0.0 2.8 3 0 0 3 3 3 0 Aspartate carbamoyltransferase regulatory chain, allosteric domain TFIIE_beta PF02186.15 OQS05295.1 - 0.056 13.7 0.1 0.84 10.0 0.0 2.8 3 0 0 3 3 3 0 TFIIE beta subunit core domain Ank PF00023.30 OQS05295.1 - 0.093 13.2 0.5 20 5.9 0.1 4.4 2 1 1 3 3 3 0 Ankyrin repeat PX PF00787.24 OQS05296.1 - 2e-10 40.6 0.1 3.6e-10 39.8 0.1 1.4 1 0 0 1 1 1 1 PX domain PX PF00787.24 OQS05299.1 - 5.5e-12 45.7 0.2 9.7e-12 44.9 0.0 1.5 2 0 0 2 2 2 1 PX domain TPR_1 PF00515.28 OQS05300.1 - 9.2e-05 22.1 0.1 2.4 8.1 0.0 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 OQS05300.1 - 0.0023 17.9 0.0 4.1 7.7 0.0 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat Exo_endo_phos PF03372.23 OQS05301.1 - 1.2e-12 47.9 0.0 1.8e-12 47.3 0.0 1.3 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.6 OQS05301.1 - 0.024 14.5 0.1 0.071 13.0 0.0 1.8 2 0 0 2 2 2 0 Endonuclease-reverse transcriptase Ank_2 PF12796.7 OQS05302.1 - 2.1e-15 57.1 1.6 1.2e-07 32.3 0.2 3.2 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OQS05302.1 - 4.2e-13 49.2 1.3 0.00068 19.9 0.0 6.0 4 3 3 7 7 7 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 OQS05302.1 - 2.1e-11 44.1 2.1 0.0019 18.8 0.0 5.0 3 2 3 6 6 6 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQS05302.1 - 1.1e-08 34.6 0.4 3.5 8.5 0.0 6.2 5 1 1 6 6 6 2 Ankyrin repeat Ank PF00023.30 OQS05302.1 - 0.0059 17.0 2.2 55 4.5 0.0 5.0 5 1 0 5 5 5 0 Ankyrin repeat mit_SMPDase PF14724.6 OQS05304.1 - 6e-16 57.6 2.7 7e-09 34.2 0.0 2.6 2 1 1 3 3 3 2 Mitochondrial-associated sphingomyelin phosphodiesterase Sugarporin_N PF11471.8 OQS05304.1 - 0.017 15.1 0.1 0.04 13.9 0.1 1.6 1 0 0 1 1 1 0 Maltoporin periplasmic N-terminal extension SpoIIE PF07228.12 OQS05305.1 - 3.4e-14 53.2 0.0 1.3e-07 31.7 0.0 2.4 2 0 0 2 2 2 2 Stage II sporulation protein E (SpoIIE) PP2C PF00481.21 OQS05305.1 - 6.7e-06 25.9 1.9 0.049 13.3 0.0 2.9 3 0 0 3 3 3 2 Protein phosphatase 2C PP2C_2 PF13672.6 OQS05305.1 - 0.0015 18.2 1.0 0.0081 15.8 0.1 2.5 2 1 0 2 2 2 1 Protein phosphatase 2C DUF3194 PF11419.8 OQS05305.1 - 0.016 15.5 0.5 0.037 14.4 0.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3194) DDE_Tnp_1_3 PF13612.6 OQS05305.1 - 0.94 9.5 3.6 0.47 10.5 0.6 2.0 2 0 0 2 2 2 0 Transposase DDE domain DUF445 PF04286.12 OQS05305.1 - 3.6 7.3 10.1 2.8 7.7 8.5 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF445) RNase_J_C PF17770.1 OQS05305.1 - 5.4 8.1 7.4 5.8 8.0 0.8 2.8 2 0 0 2 2 2 0 Ribonuclease J C-terminal domain Bromodomain PF00439.25 OQS05306.1 - 9.7e-23 80.1 0.0 1.9e-22 79.1 0.0 1.5 1 0 0 1 1 1 1 Bromodomain PHD PF00628.29 OQS05306.1 - 0.0026 17.6 1.2 0.0059 16.5 1.2 1.6 1 0 0 1 1 1 1 PHD-finger DDT PF02791.17 OQS05306.1 - 0.0059 16.9 0.0 0.015 15.6 0.0 1.6 1 0 0 1 1 1 1 DDT domain AAA_6 PF12774.7 OQS05306.1 - 0.086 11.8 0.0 0.14 11.1 0.0 1.2 1 0 0 1 1 1 0 Hydrolytic ATP binding site of dynein motor region WSD PF15613.6 OQS05306.1 - 0.65 10.5 4.9 3.5 8.1 0.1 3.7 3 1 0 3 3 3 0 Williams-Beuren syndrome DDT (WSD), D-TOX E motif Cyt-b5 PF00173.28 OQS05307.1 - 1e-18 67.3 0.0 1.6e-18 66.6 0.0 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain ARL6IP6 PF15062.6 OQS05307.1 - 0.1 12.8 0.0 0.17 12.1 0.0 1.3 1 0 0 1 1 1 0 Haemopoietic lineage transmembrane helix Fe-ADH PF00465.19 OQS05308.1 - 1.7e-101 339.7 0.0 2e-101 339.4 0.0 1.1 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.6 OQS05308.1 - 9.5e-15 55.0 1.1 1.1e-10 41.6 0.0 2.8 2 1 1 3 3 3 2 Iron-containing alcohol dehydrogenase Glyco_transf_28 PF03033.20 OQS05310.1 - 1.2e-11 44.8 0.0 2.6e-11 43.7 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.18 OQS05310.1 - 2.4e-05 23.4 0.1 3.5e-05 22.8 0.1 1.2 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase FeoB_C PF07664.12 OQS05311.1 - 0.0022 17.6 3.3 0.0093 15.6 0.1 2.4 2 0 0 2 2 2 2 Ferrous iron transport protein B C terminus ENTH PF01417.20 OQS05312.1 - 0.16 12.0 0.0 0.27 11.3 0.0 1.3 1 0 0 1 1 1 0 ENTH domain DnaJ_CXXCXGXG PF00684.19 OQS05314.1 - 6.8 7.1 19.1 0.86 10.0 13.7 2.4 2 1 0 2 2 2 0 DnaJ central domain Aa_trans PF01490.18 OQS05315.1 - 1.7e-47 162.0 25.0 2.1e-47 161.8 25.0 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein CYYR1 PF10873.8 OQS05315.1 - 0.015 15.8 0.1 0.015 15.8 0.1 2.1 2 1 0 2 2 2 0 Cysteine and tyrosine-rich protein 1 Wzy_C PF04932.15 OQS05315.1 - 1.8 8.2 10.1 0.36 10.5 0.2 3.3 3 0 0 3 3 3 0 O-Antigen ligase Calreticulin PF00262.18 OQS05316.1 - 6.7e-114 380.6 16.7 6.1e-83 278.7 5.5 2.1 1 1 1 2 2 2 2 Calreticulin family LRR_4 PF12799.7 OQS05317.1 - 3.5e-08 33.6 5.2 4.8e-05 23.6 0.7 2.8 1 1 1 2 2 2 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 OQS05317.1 - 0.00016 21.4 1.7 0.0034 17.1 0.8 2.6 1 1 2 3 3 3 3 Leucine rich repeat Glyco_tran_28_C PF04101.16 OQS05318.1 - 0.0025 17.8 0.0 0.0032 17.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain SipA_VBS PF17985.1 OQS05318.1 - 0.056 13.3 0.2 0.13 12.2 0.2 1.6 1 0 0 1 1 1 0 SipA vinculin binding site zf-CSL PF05207.13 OQS05319.1 - 8.3e-21 73.5 0.8 1.1e-20 73.1 0.8 1.1 1 0 0 1 1 1 1 CSL zinc finger zf-RING_7 PF02591.15 OQS05319.1 - 0.059 13.6 0.7 0.17 12.1 0.1 2.0 3 0 0 3 3 3 0 C4-type zinc ribbon domain GMC_oxred_N PF00732.19 OQS05320.1 - 1.7e-86 290.3 0.0 2.3e-86 289.9 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 OQS05320.1 - 3.3e-37 128.2 0.0 5.5e-37 127.5 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 OQS05320.1 - 0.00036 19.7 0.0 0.084 11.9 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.24 OQS05320.1 - 0.0025 17.5 0.6 0.0098 15.5 0.6 1.9 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 OQS05320.1 - 0.0035 17.5 0.0 0.013 15.7 0.0 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 OQS05320.1 - 0.0037 16.4 0.1 0.0053 15.8 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.14 OQS05320.1 - 0.026 13.8 0.0 0.1 11.8 0.0 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.18 OQS05320.1 - 0.031 14.5 0.0 0.092 13.0 0.0 1.8 1 0 0 1 1 1 0 TrkA-N domain Pyr_redox_3 PF13738.6 OQS05320.1 - 0.042 13.1 0.0 0.85 8.8 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Glyco_transf_28 PF03033.20 OQS05321.1 - 1.8e-12 47.5 0.0 3.1e-12 46.7 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain Glyco_tran_28_C PF04101.16 OQS05321.1 - 0.002 18.1 0.0 0.0071 16.3 0.0 1.8 2 0 0 2 2 2 1 Glycosyltransferase family 28 C-terminal domain UDPGT PF00201.18 OQS05321.1 - 0.0024 16.8 0.0 0.0034 16.2 0.0 1.2 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Thioesterase PF00975.20 OQS05322.1 - 7.1e-08 32.8 0.0 1.1e-07 32.2 0.0 1.2 1 0 0 1 1 1 1 Thioesterase domain Lipase_3 PF01764.25 OQS05322.1 - 7.1e-07 29.2 0.0 1.3e-06 28.3 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) Hydrolase_4 PF12146.8 OQS05322.1 - 0.00084 18.7 0.0 0.0013 18.0 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Peripla_BP_6 PF13458.6 OQS05322.1 - 0.013 15.2 0.1 0.018 14.7 0.1 1.1 1 0 0 1 1 1 0 Periplasmic binding protein Abhydrolase_1 PF00561.20 OQS05322.1 - 0.041 13.5 0.0 0.065 12.9 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold DUF2974 PF11187.8 OQS05322.1 - 0.082 12.5 0.0 0.34 10.4 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2974) DUF915 PF06028.11 OQS05322.1 - 0.19 11.0 0.0 0.29 10.4 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) Methyltransf_2 PF00891.18 OQS05323.1 - 9e-38 129.7 0.1 1.2e-37 129.3 0.1 1.0 1 0 0 1 1 1 1 O-methyltransferase domain TPR_2 PF07719.17 OQS05325.1 - 5.6e-06 26.1 4.5 0.00024 21.0 0.2 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.28 OQS05325.1 - 0.0002 21.1 3.2 0.0017 18.1 0.2 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.6 OQS05325.1 - 0.072 12.8 2.5 6.1 6.6 0.1 2.8 3 0 0 3 3 3 0 TPR repeat TPR_12 PF13424.6 OQS05325.1 - 0.23 11.8 1.8 0.44 10.9 0.6 2.0 2 1 0 2 2 2 0 Tetratricopeptide repeat ATP-grasp_4 PF13535.6 OQS05326.1 - 8.2e-14 51.5 0.1 2.4e-13 50.0 0.0 1.9 2 0 0 2 2 2 1 ATP-grasp domain ATP-grasp_3 PF02655.14 OQS05326.1 - 2.3e-09 37.5 0.1 3.7e-09 36.8 0.1 1.3 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.6 OQS05326.1 - 2.8e-05 23.9 0.0 0.00011 22.0 0.0 2.0 1 1 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon GARS_A PF01071.19 OQS05326.1 - 2.9e-05 23.9 0.2 5.5e-05 23.0 0.2 1.4 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain LAL_C2 PF18603.1 OQS05326.1 - 5.3e-05 23.3 0.0 0.00012 22.1 0.0 1.5 1 0 0 1 1 1 1 L-amino acid ligase C-terminal domain 2 MIF4G PF02854.19 OQS05327.1 - 2.3e-29 102.6 0.1 3.2e-29 102.1 0.1 1.3 1 0 0 1 1 1 1 MIF4G domain PAM2 PF07145.15 OQS05327.1 - 2e-05 23.9 0.6 4.2e-05 23.0 0.6 1.6 1 0 0 1 1 1 1 Ataxin-2 C-terminal region Bestrophin PF01062.21 OQS05328.1 - 7.2e-23 81.4 0.3 1e-22 80.9 0.3 1.1 1 0 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel DUF3228 PF11539.8 OQS05328.1 - 0.0035 16.9 0.3 0.0071 15.9 0.3 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF3228) MotB_plug PF13677.6 OQS05328.1 - 0.07 12.7 1.4 0.16 11.6 1.4 1.5 1 0 0 1 1 1 0 Membrane MotB of proton-channel complex MotA/MotB Aminotran_4 PF01063.19 OQS05329.1 - 2.1e-24 86.6 0.0 2.6e-24 86.3 0.0 1.1 1 0 0 1 1 1 1 Amino-transferase class IV FinO_N PF12602.8 OQS05329.1 - 0.078 13.3 0.0 0.17 12.2 0.0 1.5 1 0 0 1 1 1 0 Fertility inhibition protein N terminal EF-hand_1 PF00036.32 OQS05330.1 - 1.7e-12 45.9 0.5 4.6e-05 22.7 0.2 4.0 4 0 0 4 4 4 2 EF hand EF-hand_6 PF13405.6 OQS05330.1 - 5.6e-12 44.6 0.7 0.0011 18.7 0.0 4.6 4 0 0 4 4 4 2 EF-hand domain EF-hand_7 PF13499.6 OQS05330.1 - 8.8e-10 38.9 2.5 3.9e-09 36.8 0.0 3.1 4 0 0 4 4 4 1 EF-hand domain pair EF-hand_5 PF13202.6 OQS05330.1 - 1.6e-09 36.8 0.7 0.0028 17.1 0.2 3.3 2 0 0 2 2 2 2 EF hand MIP-T3 PF10243.9 OQS05330.1 - 3.3e-09 36.7 0.0 1e-08 35.2 0.0 1.8 1 0 0 1 1 1 1 Microtubule-binding protein MIP-T3 CH-like domain EF-hand_8 PF13833.6 OQS05330.1 - 1.1e-05 25.2 0.2 3.6e-05 23.5 0.0 2.0 1 1 1 2 2 2 1 EF-hand domain pair EF-hand_9 PF14658.6 OQS05330.1 - 0.037 14.4 0.0 0.16 12.3 0.0 2.0 2 0 0 2 2 2 0 EF-hand domain IQ PF00612.27 OQS05330.1 - 0.071 12.9 0.1 0.27 11.1 0.1 2.0 1 0 0 1 1 1 0 IQ calmodulin-binding motif KTI12 PF08433.10 OQS05330.1 - 5.9 6.2 9.2 0.95 8.9 2.9 2.5 3 0 0 3 3 3 0 Chromatin associated protein KTI12 Ank_2 PF12796.7 OQS05331.1 - 0.0012 19.4 4.3 0.04 14.5 0.3 1.9 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OQS05331.1 - 0.0018 18.6 0.2 4.5 8.2 0.0 3.5 4 0 0 4 4 4 2 Ankyrin repeat Ank_4 PF13637.6 OQS05331.1 - 0.018 15.6 0.2 3.3 8.4 0.0 2.8 2 1 0 2 2 2 0 Ankyrin repeats (many copies) Ank_5 PF13857.6 OQS05331.1 - 0.061 13.7 0.2 0.79 10.1 0.2 2.5 1 1 1 2 2 2 0 Ankyrin repeats (many copies) Ank_2 PF12796.7 OQS05332.1 - 2.4e-05 24.8 0.4 7.6e-05 23.2 0.2 1.9 2 1 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQS05332.1 - 8.3e-05 23.1 0.2 0.043 14.4 0.0 2.7 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQS05332.1 - 0.0035 17.7 0.0 0.05 14.2 0.0 2.6 2 0 0 2 2 2 1 Ankyrin repeat Ank_5 PF13857.6 OQS05332.1 - 0.0072 16.6 0.0 0.038 14.3 0.0 2.2 1 1 1 2 2 2 1 Ankyrin repeats (many copies) DUF5049 PF16468.5 OQS05332.1 - 0.07 13.0 0.7 24 4.9 0.0 3.2 2 1 1 3 3 3 0 Domain of unknown function (DUF5049) IQ PF00612.27 OQS05334.1 - 0.0022 17.6 5.5 0.35 10.8 0.4 3.4 2 0 0 2 2 2 2 IQ calmodulin-binding motif Enkurin PF13864.6 OQS05334.1 - 5.1 7.6 11.2 24 5.5 10.2 2.7 1 1 0 1 1 1 0 Calmodulin-binding CLAMP PF14769.6 OQS05334.1 - 7.9 7.0 7.2 1.4 9.4 0.1 3.3 5 0 0 5 5 5 0 Flagellar C1a complex subunit C1a-32 Ank_2 PF12796.7 OQS05335.1 - 0.0028 18.2 0.2 0.062 13.9 0.1 2.4 2 1 0 3 3 3 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OQS05335.1 - 0.0039 17.5 0.1 0.59 10.5 0.1 2.8 1 1 2 3 3 3 1 Ankyrin repeats (many copies) DUF5049 PF16468.5 OQS05335.1 - 0.027 14.4 0.9 3.7 7.5 0.0 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF5049) Ank_3 PF13606.6 OQS05335.1 - 0.054 14.1 0.0 68 4.5 0.0 3.7 3 0 0 3 3 3 0 Ankyrin repeat Thr_dehydrat_C PF00585.18 OQS05335.1 - 0.056 13.2 0.0 0.096 12.5 0.0 1.4 1 0 0 1 1 1 0 C-terminal regulatory domain of Threonine dehydratase HPS3_N PF14761.6 OQS05336.1 - 2.6e-09 36.9 0.3 1.5e-05 24.7 0.3 2.6 1 1 0 1 1 1 1 Hermansky-Pudlak syndrome 3 HPS3_Mid PF14762.6 OQS05336.1 - 0.035 12.8 0.1 0.083 11.6 0.1 1.5 1 0 0 1 1 1 0 Hermansky-Pudlak syndrome 3, middle region MFS_1 PF07690.16 OQS05337.1 - 8.4e-11 41.4 38.5 2.3e-09 36.6 17.7 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily DUF2427 PF10348.9 OQS05337.1 - 0.28 11.0 14.0 0.18 11.6 0.3 4.1 4 0 0 4 4 4 0 Domain of unknown function (DUF2427) MFS_1 PF07690.16 OQS05338.1 - 8e-13 48.0 47.6 1.1e-08 34.5 24.7 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Ank_2 PF12796.7 OQS05339.1 - 2e-27 95.6 4.8 1.7e-07 31.8 0.6 5.2 2 1 5 7 7 7 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQS05339.1 - 4e-21 75.1 7.0 0.002 18.6 0.1 8.2 4 4 3 8 8 8 8 Ankyrin repeats (many copies) Ank_5 PF13857.6 OQS05339.1 - 1.1e-15 57.4 0.8 0.0058 16.9 0.0 8.7 6 2 4 10 10 10 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQS05339.1 - 1.7e-13 49.4 3.5 1.6 9.6 0.1 10.1 10 2 2 12 12 12 2 Ankyrin repeat Ank PF00023.30 OQS05339.1 - 3.9e-05 23.9 1.4 31 5.2 0.3 7.3 5 3 0 5 5 5 0 Ankyrin repeat DUF5049 PF16468.5 OQS05339.1 - 0.033 14.1 1.7 10 6.1 0.0 5.1 5 1 2 7 7 7 0 Domain of unknown function (DUF5049) Mito_carr PF00153.27 OQS05339.1 - 0.08 12.9 0.0 0.39 10.7 0.0 2.2 3 0 0 3 3 3 0 Mitochondrial carrier protein YtfJ_HI0045 PF09695.10 OQS05339.1 - 0.15 11.6 0.0 0.39 10.3 0.0 1.6 1 0 0 1 1 1 0 Bacterial protein of unknown function (YtfJ_HI0045) MFS_1 PF07690.16 OQS05340.1 - 1.6e-20 73.3 84.5 4.2e-08 32.5 18.3 3.4 2 1 1 3 3 3 3 Major Facilitator Superfamily Ank_2 PF12796.7 OQS05342.1 - 1.1e-24 86.9 1.0 8.7e-17 61.5 0.1 3.2 1 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank PF00023.30 OQS05342.1 - 1.4e-22 79.0 0.8 0.00014 22.2 0.1 4.8 5 0 0 5 5 5 4 Ankyrin repeat Ank_5 PF13857.6 OQS05342.1 - 8.6e-21 73.7 0.6 2.5e-06 27.7 0.0 4.3 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_4 PF13637.6 OQS05342.1 - 1.4e-19 70.2 0.1 8.9e-11 42.1 0.0 2.8 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQS05342.1 - 1.5e-19 68.0 0.0 0.00013 22.1 0.0 4.8 5 0 0 5 5 5 4 Ankyrin repeat WHEP-TRS PF00458.20 OQS05342.1 - 0.051 13.7 0.1 0.14 12.3 0.1 1.8 1 0 0 1 1 1 0 WHEP-TRS domain GFRP PF06399.13 OQS05343.1 - 2.6e-13 49.6 0.2 6.1e-13 48.5 0.2 1.7 1 1 0 1 1 1 1 GTP cyclohydrolase I feedback regulatory protein (GFRP) Asp PF00026.23 OQS05344.1 - 7.3e-163 541.4 0.8 1.1e-88 297.7 0.1 2.2 2 0 0 2 2 2 2 Eukaryotic aspartyl protease Voltage_CLC PF00654.20 OQS05344.1 - 3.3e-68 230.5 28.6 3.3e-68 230.5 28.6 2.1 1 1 1 2 2 2 1 Voltage gated chloride channel TAXi_N PF14543.6 OQS05344.1 - 5.9e-17 62.5 2.8 6.3e-05 23.3 0.0 4.3 2 2 2 4 4 4 4 Xylanase inhibitor N-terminal TAXi_C PF14541.6 OQS05344.1 - 0.0042 16.9 0.0 1.3 8.7 0.0 2.5 2 0 0 2 2 2 2 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.6 OQS05344.1 - 0.026 15.1 0.1 17 6.1 0.0 3.7 3 1 0 3 3 3 0 Aspartyl protease CBS PF00571.28 OQS05344.1 - 0.035 14.5 0.0 4 8.0 0.0 2.6 2 0 0 2 2 2 0 CBS domain JmjC PF02373.22 OQS05345.1 - 8.5e-39 132.5 0.5 2.4e-38 131.1 0.5 1.9 1 0 0 1 1 1 1 JmjC domain, hydroxylase PLU-1 PF08429.11 OQS05345.1 - 1.5e-17 63.9 16.4 2.5e-14 53.2 5.8 4.2 3 2 2 5 5 5 3 PLU-1-like protein ARID PF01388.21 OQS05345.1 - 1.9e-16 60.5 0.0 4.7e-16 59.2 0.0 1.7 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain PHD PF00628.29 OQS05345.1 - 1.3e-15 57.0 43.1 1.3e-08 34.5 10.1 5.0 5 0 0 5 5 5 3 PHD-finger JmjN PF02375.17 OQS05345.1 - 3.6e-13 49.2 0.4 2e-12 46.9 0.1 2.5 2 0 0 2 2 2 1 jmjN domain zf-C5HC2 PF02928.16 OQS05345.1 - 3.3e-07 30.6 14.8 3.3e-07 30.6 14.8 2.5 2 0 0 2 2 2 1 C5HC2 zinc finger PHD_2 PF13831.6 OQS05345.1 - 0.0042 16.6 0.7 0.0042 16.6 0.7 4.3 4 0 0 4 4 4 2 PHD-finger AT_hook PF02178.19 OQS05345.1 - 0.17 11.9 22.1 0.33 11.0 5.6 3.0 3 0 0 3 3 3 0 AT hook motif HNF_C PF09354.10 OQS05345.1 - 0.23 12.5 1.7 6.4 7.9 0.0 2.8 2 0 0 2 2 2 0 HNF3 C-terminal domain DUF4316 PF14195.6 OQS05346.1 - 0.019 14.7 0.1 0.058 13.1 0.1 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4316) DUF3693 PF12472.8 OQS05346.1 - 0.64 9.7 3.1 0.84 9.3 0.3 2.7 2 1 1 3 3 3 0 Phage related protein DUF1722 PF08349.11 OQS05346.1 - 2.4 8.5 9.1 1.6 9.1 0.4 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF1722) ERM PF00769.19 OQS05346.1 - 2.7 7.7 28.8 0.89 9.3 8.2 2.6 3 0 0 3 3 3 0 Ezrin/radixin/moesin family LMBR1 PF04791.16 OQS05346.1 - 4.5 6.1 9.1 5.4 5.8 0.3 2.1 2 0 0 2 2 2 0 LMBR1-like membrane protein Ank_2 PF12796.7 OQS05348.1 - 7.9e-20 71.2 10.2 2.4e-11 44.0 1.5 2.2 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OQS05348.1 - 2e-10 39.9 1.5 0.086 13.4 0.1 3.8 4 0 0 4 4 4 3 Ankyrin repeat Ank PF00023.30 OQS05348.1 - 3.7e-10 39.8 0.6 0.0039 17.6 0.0 3.4 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 OQS05348.1 - 8.4e-10 38.7 4.2 0.00025 21.3 0.0 3.3 1 1 2 3 3 3 3 Ankyrin repeats (many copies) SAM_2 PF07647.17 OQS05348.1 - 3e-09 36.8 0.3 8.6e-09 35.4 0.1 1.7 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 OQS05348.1 - 1.2e-08 35.2 0.2 2.8e-08 34.1 0.2 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Ank_4 PF13637.6 OQS05348.1 - 2.1e-08 34.6 0.9 5.6e-06 26.8 0.0 2.7 2 1 0 3 3 3 1 Ankyrin repeats (many copies) Tctex-1 PF03645.13 OQS05349.1 - 2.1e-26 92.1 0.3 2.4e-26 92.0 0.3 1.0 1 0 0 1 1 1 1 Tctex-1 family Herpes_UL4 PF03277.13 OQS05349.1 - 0.087 12.4 0.2 0.11 12.2 0.2 1.1 1 0 0 1 1 1 0 Herpesvirus UL4 family Tyrosinase PF00264.20 OQS05350.1 - 4.4e-22 79.5 7.0 1.4e-11 45.1 0.7 2.5 1 1 1 2 2 2 2 Common central domain of tyrosinase PAN_4 PF14295.6 OQS05350.1 - 0.00019 21.3 18.6 0.0048 16.8 3.3 3.2 3 0 0 3 3 3 2 PAN domain ZirS_C PF16583.5 OQS05350.1 - 0.044 13.4 0.0 0.11 12.0 0.0 1.6 1 0 0 1 1 1 0 Zinc-regulated secreted antivirulence protein C-terminal domain ATP-synt PF00231.19 OQS05351.1 - 8.4e-74 248.8 0.4 9.6e-74 248.6 0.4 1.0 1 0 0 1 1 1 1 ATP synthase B2 PF11473.8 OQS05351.1 - 0.23 11.3 1.1 0.32 10.8 0.1 1.8 2 0 0 2 2 2 0 RNA binding protein B2 PhoLip_ATPase_C PF16212.5 OQS05352.1 - 4e-63 213.5 22.1 4e-63 213.5 22.1 2.5 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 OQS05352.1 - 9.8e-19 66.8 0.5 3.3e-18 65.1 0.5 1.9 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Cation_ATPase PF13246.6 OQS05352.1 - 2.1e-12 46.9 0.0 1e-11 44.8 0.0 2.1 2 0 0 2 2 2 1 Cation transport ATPase (P-type) E1-E2_ATPase PF00122.20 OQS05352.1 - 1.1e-10 41.3 0.0 1.1e-10 41.3 0.0 2.8 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 OQS05352.1 - 6.7e-10 39.6 1.7 1.7e-07 31.7 1.7 3.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 OQS05352.1 - 0.13 12.6 0.0 2.7 8.3 0.0 2.2 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase TPR_1 PF00515.28 OQS05354.1 - 1.5e-11 43.6 2.8 0.013 15.3 0.1 4.4 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.17 OQS05354.1 - 2.3e-10 39.8 3.8 0.13 12.5 0.1 5.1 5 0 0 5 5 5 3 Tetratricopeptide repeat Arm PF00514.23 OQS05354.1 - 9e-06 25.6 3.4 0.081 13.0 0.1 5.5 5 0 0 5 5 5 2 Armadillo/beta-catenin-like repeat TPR_14 PF13428.6 OQS05354.1 - 2.5e-05 24.7 7.6 0.41 11.6 0.7 5.7 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_12 PF13424.6 OQS05354.1 - 0.00099 19.4 1.5 0.021 15.1 0.0 3.8 4 1 0 4 4 4 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 OQS05354.1 - 0.0021 18.1 1.8 0.044 13.9 0.4 2.9 1 1 1 2 2 2 1 Fis1 C-terminal tetratricopeptide repeat TPR_11 PF13414.6 OQS05354.1 - 0.0025 17.4 0.0 0.0098 15.6 0.0 2.1 1 0 0 1 1 1 1 TPR repeat TPR_7 PF13176.6 OQS05354.1 - 0.0029 17.5 0.5 2.7 8.2 0.0 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 OQS05354.1 - 0.013 15.6 3.7 21 5.6 0.0 5.0 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_9 PF13371.6 OQS05354.1 - 0.026 14.7 1.0 1 9.5 1.5 3.4 3 1 0 3 3 3 0 Tetratricopeptide repeat DEAD PF00270.29 OQS05355.1 - 5.3e-46 156.6 0.9 1.9e-45 154.8 0.1 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OQS05355.1 - 3.3e-24 85.3 0.0 2.4e-23 82.6 0.0 2.3 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 OQS05355.1 - 8.4e-19 67.6 0.1 1.5e-18 66.7 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 OQS05355.1 - 2.2e-06 27.8 0.4 1.6e-05 25.0 0.0 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_30 PF13604.6 OQS05355.1 - 0.021 14.5 1.0 0.17 11.6 0.0 2.5 3 0 0 3 3 3 0 AAA domain Sec20 PF03908.13 OQS05356.1 - 8.2e-07 28.9 2.4 2.8e-06 27.1 0.9 2.2 1 1 1 2 2 2 1 Sec20 V-SNARE_C PF12352.8 OQS05356.1 - 2.1e-05 24.7 2.7 2.1e-05 24.7 2.7 1.9 2 0 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus DUF4407 PF14362.6 OQS05356.1 - 0.00019 20.9 3.7 0.00024 20.6 3.7 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4407) DUF2594 PF10769.9 OQS05356.1 - 0.052 13.6 0.0 0.18 11.9 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2594) FA_desaturase PF00487.24 OQS05357.1 - 1.6e-44 152.7 29.5 4.7e-23 82.3 10.1 2.3 2 0 0 2 2 2 2 Fatty acid desaturase Lipid_DES PF08557.10 OQS05357.1 - 1.7e-34 117.0 1.8 2.6e-16 58.8 0.4 2.5 2 0 0 2 2 2 2 Sphingolipid Delta4-desaturase (DES) Peptidase_M8 PF01457.16 OQS05357.1 - 0.014 14.1 1.5 0.26 9.9 0.1 2.1 2 0 0 2 2 2 0 Leishmanolysin Kelch_6 PF13964.6 OQS05357.1 - 1 9.8 4.8 0.95 9.8 0.7 3.1 3 0 0 3 3 3 0 Kelch motif DUF4396 PF14342.6 OQS05357.1 - 6.7 7.1 13.1 0.73 10.2 1.1 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4396) RhoGEF PF00621.20 OQS05358.1 - 2.7e-24 86.4 0.7 4.1e-24 85.8 0.7 1.3 1 0 0 1 1 1 1 RhoGEF domain IQ_SEC7_PH PF16453.5 OQS05358.1 - 0.029 14.3 0.0 0.94 9.5 0.0 2.3 2 0 0 2 2 2 0 PH domain Glyco_hydro_1 PF00232.18 OQS05359.1 - 4.1e-124 414.4 0.1 6.5e-124 413.8 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 EBV-NA3 PF05009.12 OQS05360.1 - 0.36 10.3 3.3 0.59 9.6 3.3 1.3 1 0 0 1 1 1 0 Epstein-Barr virus nuclear antigen 3 (EBNA-3) DUF4055 PF13264.6 OQS05360.1 - 3.4 7.8 6.7 0.24 11.6 1.7 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4055) FYVE PF01363.21 OQS05361.1 - 1e-06 28.8 12.5 3e-06 27.3 12.5 1.8 1 0 0 1 1 1 1 FYVE zinc finger START PF01852.19 OQS05361.1 - 4.8e-06 26.1 0.0 8.4e-06 25.3 0.0 1.3 1 0 0 1 1 1 1 START domain FYVE_2 PF02318.16 OQS05361.1 - 0.00074 19.7 5.0 0.00074 19.7 5.0 1.8 2 0 0 2 2 2 1 FYVE-type zinc finger IBR PF01485.21 OQS05361.1 - 2.9 8.2 9.8 5.3 7.3 5.2 2.6 2 0 0 2 2 2 0 IBR domain, a half RING-finger domain Metallophos PF00149.28 OQS05362.1 - 4.9e-17 63.1 5.7 9.4e-17 62.2 5.7 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 OQS05362.1 - 1.8e-05 25.0 5.1 2e-05 24.8 2.1 2.4 2 1 0 2 2 2 1 Calcineurin-like phosphoesterase superfamily domain DUF1096 PF06493.11 OQS05363.1 - 0.27 11.7 3.9 12 6.4 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1096) Asn_synthase PF00733.21 OQS05365.1 - 3.2e-95 319.8 10.7 2.7e-57 195.1 0.1 3.3 2 1 1 3 3 3 2 Asparagine synthase GATase_7 PF13537.6 OQS05365.1 - 2.2e-43 147.1 0.0 4.7e-43 146.0 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.6 OQS05365.1 - 2.4e-32 111.9 0.0 4.6e-32 111.0 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain DUF3700 PF12481.8 OQS05365.1 - 7.2e-15 55.1 0.1 3.2e-14 52.9 0.1 2.1 3 0 0 3 3 3 1 Aluminium induced protein EF-hand_6 PF13405.6 OQS05365.1 - 1.7e-12 46.2 0.3 0.0013 18.5 0.0 4.2 3 0 0 3 3 3 2 EF-hand domain EF-hand_7 PF13499.6 OQS05365.1 - 8.1e-11 42.2 0.2 0.00035 21.0 0.1 3.1 2 0 0 2 2 2 2 EF-hand domain pair WW PF00397.26 OQS05365.1 - 1.6e-10 40.9 0.0 3.9e-08 33.2 0.0 2.6 2 0 0 2 2 2 1 WW domain EF-hand_1 PF00036.32 OQS05365.1 - 3.8e-10 38.6 3.6 0.00044 19.6 0.0 4.2 4 0 0 4 4 4 2 EF hand EF-hand_5 PF13202.6 OQS05365.1 - 2.4e-05 23.6 2.0 0.047 13.2 0.0 3.3 4 0 0 4 4 4 2 EF hand EF-hand_8 PF13833.6 OQS05365.1 - 3.5e-05 23.5 2.9 0.6 10.0 0.0 3.6 2 1 1 3 3 3 2 EF-hand domain pair NAD_synthase PF02540.17 OQS05365.1 - 0.062 12.4 0.3 0.57 9.2 0.0 2.3 2 0 0 2 2 2 0 NAD synthase PAS PF00989.25 OQS05365.1 - 0.19 11.7 1.7 0.31 11.1 0.0 2.2 2 0 0 2 2 2 0 PAS fold IQ PF00612.27 OQS05365.1 - 0.53 10.2 3.7 2.2 8.3 0.9 2.8 2 0 0 2 2 2 0 IQ calmodulin-binding motif DUF3817 PF12823.7 OQS05367.1 - 0.034 15.0 2.8 0.13 13.1 2.8 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3817) DUF2367 PF10164.9 OQS05367.1 - 0.058 13.9 0.2 0.16 12.5 0.0 1.8 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2367) RIO1 PF01163.22 OQS05368.1 - 1.6e-74 249.6 0.0 1.6e-74 249.6 0.0 2.3 2 0 0 2 2 2 1 RIO1 family Pkinase_fungal PF17667.1 OQS05368.1 - 0.00093 18.1 3.7 0.004 16.0 0.0 2.2 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 OQS05368.1 - 0.012 15.6 0.0 1.7 8.5 0.0 2.9 3 0 0 3 3 3 0 Phosphotransferase enzyme family DNA_pol_phi PF04931.13 OQS05368.1 - 0.54 8.3 21.3 0.66 8.0 21.3 1.3 1 0 0 1 1 1 0 DNA polymerase phi CDC45 PF02724.14 OQS05368.1 - 0.96 7.7 23.7 1.2 7.3 23.7 1.1 1 0 0 1 1 1 0 CDC45-like protein Cwf_Cwc_15 PF04889.12 OQS05368.1 - 1.5 8.5 32.5 2.9 7.6 32.5 1.5 1 1 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein VIR_N PF15912.5 OQS05368.1 - 9.2 5.8 12.6 13 5.3 12.6 1.3 1 0 0 1 1 1 0 Virilizer, N-terminal Ig_mannosidase PF17753.1 OQS05370.1 - 1.7e-12 46.9 0.2 4.5e-12 45.5 0.2 1.7 1 0 0 1 1 1 1 Ig-fold domain Glyco_hydro_2 PF00703.21 OQS05370.1 - 1.2e-08 35.6 0.0 2.3e-08 34.7 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 Glyco_hydro_2_N PF02837.18 OQS05370.1 - 0.022 14.7 0.0 0.063 13.2 0.0 1.7 1 0 0 1 1 1 0 Glycosyl hydrolases family 2, sugar binding domain Elf1 PF05129.13 OQS05371.1 - 1.2e-29 102.1 6.1 1.4e-29 102.0 6.1 1.0 1 0 0 1 1 1 1 Transcription elongation factor Elf1 like zf-Sec23_Sec24 PF04810.15 OQS05371.1 - 0.35 11.0 0.3 0.35 11.0 0.3 2.3 1 1 1 2 2 2 0 Sec23/Sec24 zinc finger Carboxyl_trans PF01039.22 OQS05372.1 - 2e-194 646.9 0.2 2.3e-194 646.6 0.2 1.0 1 0 0 1 1 1 1 Carboxyl transferase domain MdcE PF06833.11 OQS05372.1 - 0.00048 19.7 0.2 0.0033 16.9 0.0 2.2 2 0 0 2 2 2 1 Malonate decarboxylase gamma subunit (MdcE) YbjN PF10722.9 OQS05373.1 - 0.039 14.0 0.0 0.12 12.4 0.0 1.8 1 0 0 1 1 1 0 Putative bacterial sensory transduction regulator fn3 PF00041.21 OQS05373.1 - 0.041 14.2 0.0 3.5 8.1 0.0 3.6 3 0 0 3 3 3 0 Fibronectin type III domain SURF2 PF05477.11 OQS05374.1 - 1.3 8.7 12.5 13 5.4 12.5 2.1 1 1 0 1 1 1 0 Surfeit locus protein 2 (SURF2) PPR_2 PF13041.6 OQS05375.1 - 2.1e-22 79.0 4.7 0.00011 22.3 0.1 9.4 7 3 3 10 10 10 6 PPR repeat family PPR PF01535.20 OQS05375.1 - 2.8e-16 58.5 10.5 0.023 14.9 0.0 11.6 12 0 0 12 12 12 3 PPR repeat PPR_3 PF13812.6 OQS05375.1 - 6.5e-15 55.0 3.4 0.044 13.8 0.0 7.4 6 1 1 7 7 7 3 Pentatricopeptide repeat domain PPR_long PF17177.4 OQS05375.1 - 1.1e-12 47.7 7.7 3.5e-06 26.5 2.1 6.4 4 2 3 7 7 7 4 Pentacotripeptide-repeat region of PRORP Glyoxalase PF00903.25 OQS05375.1 - 1.9e-05 24.8 1.5 9.6e-05 22.6 0.4 2.7 2 0 0 2 2 2 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily TPR_19 PF14559.6 OQS05375.1 - 2.9e-05 24.5 5.9 16 6.1 0.1 7.2 7 0 0 7 7 7 0 Tetratricopeptide repeat PPR_1 PF12854.7 OQS05375.1 - 0.00098 18.8 0.0 2.5 7.9 0.0 4.0 3 0 0 3 3 3 1 PPR repeat TPR_14 PF13428.6 OQS05375.1 - 0.0018 19.0 4.6 11 7.1 0.0 7.5 9 0 0 9 9 7 1 Tetratricopeptide repeat Glyoxalase_4 PF13669.6 OQS05375.1 - 0.0081 16.4 0.1 0.053 13.8 0.1 2.4 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.6 OQS05375.1 - 0.052 13.6 0.4 0.84 9.7 0.1 2.6 2 1 0 2 2 2 0 Glyoxalase-like domain TPR_6 PF13174.6 OQS05375.1 - 0.057 14.1 5.4 20 6.1 0.0 5.8 7 0 0 7 7 7 0 Tetratricopeptide repeat Clathrin PF00637.20 OQS05375.1 - 0.41 10.5 4.2 57 3.6 0.1 4.9 4 1 1 5 5 5 0 Region in Clathrin and VPS Reprolysin_5 PF13688.6 OQS05376.1 - 1.2e-18 68.0 1.1 3.9e-18 66.3 1.1 1.9 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_4 PF13583.6 OQS05376.1 - 9.3e-14 51.5 0.5 2.8e-13 50.0 0.5 1.8 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like His_Phos_2 PF00328.22 OQS05376.1 - 1.6e-12 47.5 0.0 1.1e-10 41.4 0.0 2.4 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Reprolysin_2 PF13574.6 OQS05376.1 - 1.1e-10 41.7 0.6 2.6e-10 40.5 0.6 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.6 OQS05376.1 - 2.3e-09 37.8 0.3 1.1e-08 35.6 0.3 2.3 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like TSP_1 PF00090.19 OQS05376.1 - 0.00071 19.7 4.5 0.00071 19.7 4.5 2.6 2 0 0 2 2 2 1 Thrombospondin type 1 domain Metallopep PF12044.8 OQS05376.1 - 0.099 11.2 0.0 0.17 10.4 0.0 1.2 1 0 0 1 1 1 0 Putative peptidase family RRM_1 PF00076.22 OQS05377.1 - 1.2e-57 191.6 0.1 9.5e-19 67.0 0.1 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 OQS05377.1 - 1.5e-10 41.0 0.0 9.1e-06 25.7 0.0 3.5 3 1 0 3 3 3 2 RNA recognition motif RRM_5 PF13893.6 OQS05377.1 - 5.2e-06 26.1 0.0 0.057 13.0 0.0 2.9 2 1 1 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 OQS05377.1 - 8.6e-05 22.5 0.1 2 8.5 0.0 3.3 3 0 0 3 3 3 2 Nup53/35/40-type RNA recognition motif DUF1866 PF08952.11 OQS05377.1 - 0.00033 20.5 0.0 0.059 13.2 0.0 2.9 2 1 0 3 3 3 1 Domain of unknown function (DUF1866) RL PF17797.1 OQS05377.1 - 0.0021 17.9 0.0 0.3 11.0 0.0 3.2 3 0 0 3 3 3 1 RL domain DUF4651 PF15513.6 OQS05377.1 - 0.015 15.1 0.0 0.11 12.4 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4651) RRM_3 PF08777.11 OQS05377.1 - 0.025 14.6 0.0 5.6 7.1 0.0 3.2 3 0 0 3 3 3 0 RNA binding motif Sugar_transport PF06800.12 OQS05378.1 - 0.02 14.2 0.2 0.024 14.0 0.2 1.0 1 0 0 1 1 1 0 Sugar transport protein GPR15L PF15854.5 OQS05378.1 - 0.51 10.6 3.6 2.9 8.2 0.8 2.2 2 0 0 2 2 2 0 G-protein coupled receptor ligand 15 FAD_binding_1 PF00667.20 OQS05379.1 - 1.4e-22 80.4 0.0 2.2e-22 79.7 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.21 OQS05379.1 - 6.2e-14 52.6 0.0 1.3e-13 51.6 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Oxidored-like PF09791.9 OQS05379.1 - 9.1e-07 28.5 2.1 2.7e-06 27.0 2.1 1.8 1 0 0 1 1 1 1 Oxidoreductase-like protein, N-terminal DSPc PF00782.20 OQS05380.1 - 7.9e-32 109.9 0.0 1.6e-31 108.9 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 OQS05380.1 - 0.0032 17.1 0.0 0.0067 16.0 0.0 1.5 1 0 0 1 1 1 1 Protein-tyrosine phosphatase FYVE PF01363.21 OQS05382.1 - 1.9e-12 47.2 33.0 3.7e-06 27.0 12.1 2.5 2 0 0 2 2 2 2 FYVE zinc finger START PF01852.19 OQS05382.1 - 2.2e-12 46.8 0.4 1.9e-05 24.2 0.0 2.8 3 0 0 3 3 3 2 START domain FYVE_2 PF02318.16 OQS05382.1 - 1.8e-10 41.1 15.3 7.2e-05 23.0 3.3 2.6 2 0 0 2 2 2 2 FYVE-type zinc finger Siva PF05458.12 OQS05382.1 - 0.0057 16.4 16.4 0.18 11.5 4.4 2.5 2 0 0 2 2 2 2 Cd27 binding protein (Siva) IBR PF01485.21 OQS05382.1 - 0.027 14.7 16.9 0.96 9.7 4.1 2.9 2 0 0 2 2 2 0 IBR domain, a half RING-finger domain Cript PF10235.9 OQS05382.1 - 0.088 13.4 9.1 0.47 11.1 1.4 3.2 2 0 0 2 2 2 0 Microtubule-associated protein CRIPT Ser_hydrolase PF06821.13 OQS05382.1 - 0.11 12.4 0.0 0.2 11.5 0.0 1.4 1 0 0 1 1 1 0 Serine hydrolase zinc_ribbon_4 PF13717.6 OQS05382.1 - 0.2 11.6 27.2 0.32 11.0 10.4 2.8 2 0 0 2 2 2 0 zinc-ribbon domain Zn_ribbon_17 PF17120.5 OQS05382.1 - 6.2 6.5 27.6 3.3 7.4 7.7 3.3 2 1 0 3 3 3 0 Zinc-ribbon, C4HC2 type Cu-oxidase_3 PF07732.15 OQS05383.1 - 2.3e-14 53.4 1.7 3.9e-06 26.9 1.6 3.1 2 1 1 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.22 OQS05383.1 - 0.037 14.1 0.0 0.17 12.0 0.0 1.9 2 0 0 2 2 2 0 Multicopper oxidase Ribosomal_L7Ae PF01248.26 OQS05384.1 - 2.2e-10 40.1 0.2 4.1e-10 39.3 0.2 1.5 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family PRKG1_interact PF15898.5 OQS05385.1 - 0.83 10.6 11.2 29 5.7 0.9 2.5 1 1 1 2 2 2 0 cGMP-dependent protein kinase interacting domain HR1 PF02185.16 OQS05385.1 - 1.4 9.1 14.4 0.14 12.3 4.9 2.6 2 0 0 2 2 2 0 Hr1 repeat YlqD PF11068.8 OQS05385.1 - 2.1 8.7 5.1 4.2 7.7 5.1 1.5 1 0 0 1 1 1 0 YlqD protein bZIP_1 PF00170.21 OQS05385.1 - 6.7 6.9 11.9 23 5.2 7.4 2.5 2 0 0 2 2 2 0 bZIP transcription factor FAA_hydrolase PF01557.18 OQS05386.1 - 6.4e-66 222.1 0.0 8.4e-66 221.7 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family Myotub-related PF06602.14 OQS05387.1 - 1.2e-127 425.7 0.0 1.9e-127 425.0 0.0 1.4 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain UPF0176_N PF17773.1 OQS05387.1 - 4.2e-12 46.2 0.0 1e-11 45.0 0.0 1.7 1 0 0 1 1 1 1 UPF0176 acylphosphatase like domain Rhodanese PF00581.20 OQS05387.1 - 2.9e-10 40.6 0.0 9.5e-10 39.0 0.0 2.0 1 0 0 1 1 1 1 Rhodanese-like domain E1-E2_ATPase PF00122.20 OQS05387.1 - 0.0016 18.0 0.0 0.0029 17.2 0.0 1.4 1 0 0 1 1 1 1 E1-E2 ATPase DSPc PF00782.20 OQS05387.1 - 0.012 15.5 0.0 0.033 14.0 0.0 1.7 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain Rhodanese_C PF12368.8 OQS05387.1 - 0.017 15.5 0.2 0.057 13.8 0.2 1.9 1 0 0 1 1 1 0 Rhodanase C-terminal Y_phosphatase3 PF13350.6 OQS05387.1 - 0.025 14.5 0.0 0.066 13.2 0.0 1.7 1 0 0 1 1 1 0 Tyrosine phosphatase family Y_phosphatase PF00102.27 OQS05387.1 - 0.045 13.3 0.0 0.13 11.8 0.0 1.7 1 0 0 1 1 1 0 Protein-tyrosine phosphatase GRAM PF02893.20 OQS05387.1 - 0.061 13.2 0.0 0.15 11.9 0.0 1.6 1 0 0 1 1 1 0 GRAM domain 3-PAP PF12578.8 OQS05387.1 - 0.067 12.9 0.1 0.32 10.7 0.1 2.2 1 0 0 1 1 1 0 Myotubularin-associated protein DUF2430 PF10353.9 OQS05387.1 - 0.1 13.0 0.0 0.23 11.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2430) zinc_ribbon_9 PF14369.6 OQS05387.1 - 0.27 11.5 1.3 0.75 10.1 0.9 1.9 2 0 0 2 2 1 0 zinc-ribbon NAD_binding_8 PF13450.6 OQS05389.1 - 3e-10 40.2 0.0 6.8e-10 39.0 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 OQS05389.1 - 5.9e-08 32.4 0.0 1.7e-07 30.9 0.0 1.8 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase DAO PF01266.24 OQS05389.1 - 8.1e-07 28.9 0.0 0.00075 19.2 0.0 2.6 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 OQS05389.1 - 0.029 13.6 0.0 0.69 9.1 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 OQS05389.1 - 0.15 11.3 0.0 0.27 10.4 0.0 1.4 1 0 0 1 1 1 0 Thi4 family Pkinase PF00069.25 OQS05391.1 - 1.7e-151 503.0 0.1 9.8e-58 195.6 0.0 3.1 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 OQS05391.1 - 1.3e-53 181.9 0.0 6.4e-19 68.2 0.0 3.3 3 0 0 3 3 3 3 Protein tyrosine kinase Kinase-like PF14531.6 OQS05391.1 - 8.7e-13 48.2 0.0 0.00048 19.5 0.0 3.4 3 0 0 3 3 3 3 Kinase-like Kdo PF06293.14 OQS05391.1 - 1.9e-06 27.4 0.4 0.004 16.5 0.1 2.4 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family Bac_DNA_binding PF00216.21 OQS05391.1 - 0.0011 19.1 0.0 4.6 7.5 0.0 3.4 3 0 0 3 3 3 2 Bacterial DNA-binding protein YrbL-PhoP_reg PF10707.9 OQS05391.1 - 0.012 15.2 0.1 2.7 7.5 0.0 2.4 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL CotH PF08757.11 OQS05391.1 - 0.063 12.8 0.1 0.13 11.7 0.1 1.4 1 0 0 1 1 1 0 CotH kinase protein TPR_20 PF14561.6 OQS05391.1 - 0.13 12.6 0.2 3.5 8.0 0.0 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat RuvA_C PF07499.13 OQS05391.1 - 0.15 12.6 0.1 11 6.6 0.0 3.1 3 0 0 3 3 3 0 RuvA, C-terminal domain Pkinase PF00069.25 OQS05392.1 - 6e-58 196.3 0.0 1e-57 195.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain AAA PF00004.29 OQS05392.1 - 2.2e-38 131.6 0.0 4.4e-38 130.7 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Pkinase_Tyr PF07714.17 OQS05392.1 - 1.9e-21 76.5 0.0 3e-21 75.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Prot_ATP_ID_OB PF16450.5 OQS05392.1 - 1.5e-17 63.2 0.1 3.3e-17 62.2 0.1 1.6 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_lid_3 PF17862.1 OQS05392.1 - 5.2e-11 42.2 0.3 2e-10 40.3 0.3 2.0 1 0 0 1 1 1 1 AAA+ lid domain Kinase-like PF14531.6 OQS05392.1 - 2.7e-10 40.1 0.1 3.6e-09 36.3 0.0 2.1 2 0 0 2 2 2 1 Kinase-like AAA_2 PF07724.14 OQS05392.1 - 1.3e-06 28.6 1.2 2.4e-06 27.8 0.0 2.0 3 0 0 3 3 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 OQS05392.1 - 9.2e-06 25.7 0.4 9.3e-05 22.4 0.0 2.8 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 OQS05392.1 - 2.1e-05 25.0 0.1 0.00011 22.7 0.1 2.2 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 OQS05392.1 - 0.0002 21.6 0.1 0.0085 16.4 0.1 2.8 1 1 0 1 1 1 1 AAA domain Kdo PF06293.14 OQS05392.1 - 0.00055 19.3 0.4 0.0011 18.3 0.4 1.5 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family AAA_33 PF13671.6 OQS05392.1 - 0.00092 19.4 0.0 0.0024 18.1 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 OQS05392.1 - 0.0016 18.3 1.0 0.5 10.1 0.0 2.4 2 0 0 2 2 2 1 AAA domain RuvB_N PF05496.12 OQS05392.1 - 0.0058 16.4 0.0 0.02 14.6 0.0 1.9 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain CPT PF07931.12 OQS05392.1 - 0.013 15.3 0.1 0.042 13.7 0.0 1.8 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein AAA_24 PF13479.6 OQS05392.1 - 0.018 14.8 0.9 1 9.1 0.0 3.0 2 0 0 2 2 2 0 AAA domain FlxA PF14282.6 OQS05392.1 - 0.019 15.0 0.6 0.087 12.8 0.4 2.1 2 0 0 2 2 2 0 FlxA-like protein AAA_25 PF13481.6 OQS05392.1 - 0.026 14.1 0.1 6.5 6.3 0.1 2.9 3 0 0 3 3 3 0 AAA domain RIO1 PF01163.22 OQS05392.1 - 0.029 14.0 0.6 0.063 12.9 0.6 1.5 1 0 0 1 1 1 0 RIO1 family AAA_14 PF13173.6 OQS05392.1 - 0.033 14.2 0.0 0.14 12.2 0.0 2.1 1 0 0 1 1 1 0 AAA domain TIP49 PF06068.13 OQS05392.1 - 0.037 13.2 0.2 0.14 11.4 0.0 2.0 2 0 0 2 2 2 0 TIP49 P-loop domain APH PF01636.23 OQS05392.1 - 0.048 13.6 0.1 0.23 11.4 0.0 1.9 1 1 1 2 2 2 0 Phosphotransferase enzyme family Mg_chelatase PF01078.21 OQS05392.1 - 0.051 13.0 0.0 0.12 11.7 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_18 PF13238.6 OQS05392.1 - 0.052 14.1 0.1 0.27 11.8 0.0 2.4 2 1 0 2 2 1 0 AAA domain IstB_IS21 PF01695.17 OQS05392.1 - 0.066 12.9 0.1 0.14 11.9 0.1 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein Sigma54_activat PF00158.26 OQS05392.1 - 0.13 11.9 0.0 0.47 10.1 0.0 2.0 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA_3 PF07726.11 OQS05392.1 - 0.14 12.0 0.1 0.78 9.6 0.0 2.2 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Pkinase PF00069.25 OQS05393.1 - 4.1e-72 242.7 0.1 4.7e-72 242.5 0.1 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQS05393.1 - 7.3e-37 127.1 0.0 8e-37 126.9 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 OQS05393.1 - 9.3e-06 25.1 0.0 1.4e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 OQS05393.1 - 5e-05 22.8 0.0 6.3e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 OQS05393.1 - 0.0038 16.0 0.0 0.0055 15.5 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Chordopox_A35R PF05989.12 OQS05393.1 - 0.068 13.0 0.8 0.15 12.0 0.4 1.8 2 0 0 2 2 2 0 Chordopoxvirus A35R protein APH PF01636.23 OQS05393.1 - 0.12 12.3 0.0 0.38 10.6 0.0 1.7 1 1 1 2 2 2 0 Phosphotransferase enzyme family Pkinase PF00069.25 OQS05394.1 - 5.9e-150 497.9 0.0 9e-74 248.2 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain AAA_5 PF07728.14 OQS05394.1 - 3e-92 305.8 0.0 1.1e-38 132.4 0.0 3.6 3 0 0 3 3 3 3 AAA domain (dynein-related subfamily) Pkinase_Tyr PF07714.17 OQS05394.1 - 2e-69 233.7 0.0 1.6e-33 116.1 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Kdo PF06293.14 OQS05394.1 - 8.6e-10 38.3 0.1 0.00082 18.8 0.0 2.5 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 OQS05394.1 - 6.1e-06 25.3 0.0 0.011 14.5 0.0 2.7 2 0 0 2 2 2 2 Fungal protein kinase Choline_kinase PF01633.20 OQS05394.1 - 0.0001 22.0 0.7 0.14 11.7 0.1 2.9 2 0 0 2 2 2 2 Choline/ethanolamine kinase AAA_16 PF13191.6 OQS05394.1 - 0.00013 22.4 5.5 0.047 14.1 0.0 4.6 3 1 0 3 3 3 1 AAA ATPase domain APH PF01636.23 OQS05394.1 - 0.00025 21.0 0.2 0.96 9.3 0.0 3.8 2 2 1 3 3 3 1 Phosphotransferase enzyme family Mg_chelatase PF01078.21 OQS05394.1 - 0.0011 18.4 1.3 0.11 11.9 0.0 3.7 3 1 0 3 3 3 1 Magnesium chelatase, subunit ChlI YrbL-PhoP_reg PF10707.9 OQS05394.1 - 0.0017 17.9 0.4 0.93 9.0 0.0 3.1 3 0 0 3 3 3 2 PhoP regulatory network protein YrbL Pox_ser-thr_kin PF05445.11 OQS05394.1 - 0.0037 16.3 0.5 0.8 8.6 0.1 2.3 2 0 0 2 2 2 2 Poxvirus serine/threonine protein kinase AAA_22 PF13401.6 OQS05394.1 - 0.0055 17.0 1.5 7.1 6.9 0.1 3.9 3 2 0 3 3 3 2 AAA domain AAA_3 PF07726.11 OQS05394.1 - 0.012 15.5 0.0 2.8 7.8 0.0 3.4 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 OQS05394.1 - 0.025 14.1 0.1 0.13 11.8 0.1 2.2 3 0 0 3 3 3 0 P-loop containing dynein motor region AAA_29 PF13555.6 OQS05394.1 - 0.053 13.3 0.0 10 5.9 0.0 2.6 2 0 0 2 2 2 0 P-loop containing region of AAA domain HTH_Tnp_Tc5 PF03221.16 OQS05395.1 - 3.6e-12 46.1 0.1 9.5e-12 44.8 0.1 1.7 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain HTH_ABP1_N PF18107.1 OQS05395.1 - 0.00073 19.2 0.1 0.0018 17.9 0.1 1.6 1 0 0 1 1 1 1 Fission yeast centromere protein N-terminal domain Carn_acyltransf PF00755.20 OQS05396.1 - 1.3e-204 681.2 0.0 1.5e-204 681.0 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase BT1 PF03092.16 OQS05398.1 - 1e-12 47.1 18.4 1.2e-09 36.9 5.9 2.9 2 1 0 2 2 2 2 BT1 family Ank_2 PF12796.7 OQS05399.1 - 2e-15 57.2 5.0 1.7e-05 25.3 0.3 4.3 2 1 2 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQS05399.1 - 6.3e-14 52.1 8.2 7.6e-07 29.6 0.1 6.0 2 2 2 5 5 5 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 OQS05399.1 - 3.4e-10 40.0 4.2 0.00027 21.2 0.1 6.2 3 2 5 8 8 8 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQS05399.1 - 9.9e-10 37.8 3.7 5.2 8.0 0.0 7.7 7 2 2 9 9 9 3 Ankyrin repeat DUF5049 PF16468.5 OQS05399.1 - 0.00032 20.5 3.5 6 6.8 0.0 5.4 2 1 4 6 6 6 1 Domain of unknown function (DUF5049) DUF3447 PF11929.8 OQS05399.1 - 0.0014 18.6 1.4 0.94 9.5 0.0 3.7 1 1 2 3 3 3 1 Domain of unknown function (DUF3447) Ank PF00023.30 OQS05399.1 - 0.071 13.6 3.6 46 4.7 0.0 5.4 5 2 0 5 5 5 0 Ankyrin repeat ADK PF00406.22 OQS05400.1 - 3.4e-48 163.6 0.0 4e-48 163.3 0.0 1.0 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 OQS05400.1 - 3.3e-22 79.4 0.0 5.7e-22 78.6 0.0 1.4 2 0 0 2 2 1 1 AAA domain ADK_lid PF05191.14 OQS05400.1 - 2.6e-11 43.3 1.1 6.6e-11 42.0 1.3 1.6 2 0 0 2 2 1 1 Adenylate kinase, active site lid AAA_33 PF13671.6 OQS05400.1 - 0.00011 22.4 0.0 0.00019 21.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 OQS05400.1 - 0.00039 21.0 0.0 0.00059 20.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 OQS05400.1 - 0.0047 17.4 0.0 0.0071 16.8 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) A2L_zn_ribbon PF08792.10 OQS05400.1 - 0.0051 16.5 1.0 0.038 13.7 0.1 2.2 2 0 0 2 2 2 1 A2L zinc ribbon domain AAA_28 PF13521.6 OQS05400.1 - 0.0071 16.6 0.0 0.0097 16.2 0.0 1.2 1 0 0 1 1 1 1 AAA domain Cytidylate_kin PF02224.18 OQS05400.1 - 0.011 15.5 0.0 0.021 14.6 0.0 1.5 1 1 0 1 1 1 0 Cytidylate kinase Mg_chelatase PF01078.21 OQS05400.1 - 0.036 13.4 0.0 0.05 13.0 0.0 1.2 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI DUF983 PF06170.12 OQS05400.1 - 0.042 14.3 0.2 2.4 8.6 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF983) Hydin_ADK PF17213.3 OQS05400.1 - 0.045 14.0 0.1 0.62 10.3 0.0 2.5 2 1 1 3 3 3 0 Hydin Adenylate kinase-like domain RuvB_N PF05496.12 OQS05400.1 - 0.059 13.1 0.0 0.098 12.4 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain zinc_ribbon_4 PF13717.6 OQS05400.1 - 0.069 13.1 0.9 0.6 10.1 0.0 2.4 2 0 0 2 2 2 0 zinc-ribbon domain HypA PF01155.19 OQS05400.1 - 0.071 13.1 0.0 0.11 12.5 0.0 1.3 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DUF1103 PF06513.11 OQS05400.1 - 0.081 12.5 0.0 0.16 11.6 0.0 1.4 1 0 0 1 1 1 0 Repeat of unknown function (DUF1103) zf-RRN7 PF11781.8 OQS05400.1 - 0.097 12.4 1.1 0.59 9.9 0.0 2.1 2 0 0 2 2 2 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 DZR PF12773.7 OQS05400.1 - 0.11 12.5 0.1 0.24 11.4 0.1 1.5 1 1 0 1 1 1 0 Double zinc ribbon RNA_helicase PF00910.22 OQS05400.1 - 0.15 12.5 0.0 0.56 10.6 0.0 2.0 1 1 0 1 1 1 0 RNA helicase zf-ribbon_3 PF13248.6 OQS05400.1 - 0.2 11.1 2.0 11 5.5 0.1 2.3 2 0 0 2 2 2 0 zinc-ribbon domain PX PF00787.24 OQS05401.1 - 4.2e-16 58.9 0.0 9.2e-16 57.8 0.0 1.5 1 0 0 1 1 1 1 PX domain Peptidase_C92 PF05708.12 OQS05401.1 - 1.9e-06 28.0 0.0 6.2e-06 26.4 0.0 1.9 1 0 0 1 1 1 1 Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family HMG_box PF00505.19 OQS05403.1 - 6.1e-07 29.8 0.8 6.1e-07 29.8 0.8 2.0 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.10 OQS05403.1 - 0.01 16.4 2.3 0.014 15.9 0.9 2.0 2 0 0 2 2 2 0 HMG-box domain GAGA_bind PF06217.12 OQS05403.1 - 0.12 12.6 10.6 0.16 12.2 10.6 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family DUF572 PF04502.13 OQS05403.1 - 0.15 11.7 9.5 0.2 11.3 9.5 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) CAML PF14963.6 OQS05403.1 - 0.19 11.8 2.6 0.29 11.2 2.6 1.3 1 0 0 1 1 1 0 Calcium signal-modulating cyclophilin ligand UPF0242 PF06785.11 OQS05403.1 - 0.35 11.0 7.2 0.25 11.4 5.8 1.5 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus PNP_phzG_C PF10590.9 OQS05403.1 - 0.57 10.3 3.2 5.3 7.2 0.0 2.4 2 0 0 2 2 2 0 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region ZapB PF06005.12 OQS05403.1 - 7.6 7.1 11.0 3.4 8.2 3.3 2.2 2 0 0 2 2 2 0 Cell division protein ZapB His_Phos_1 PF00300.22 OQS05404.1 - 1.9e-44 151.7 0.0 2.3e-44 151.4 0.0 1.0 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Far-17a_AIG1 PF04750.14 OQS05405.1 - 2.9e-07 30.0 16.9 4.3e-07 29.4 16.9 1.2 1 0 0 1 1 1 1 FAR-17a/AIG1-like protein DUF1295 PF06966.12 OQS05406.1 - 2.5e-05 23.9 4.0 4.3e-05 23.2 4.0 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF1295) ERG4_ERG24 PF01222.17 OQS05406.1 - 5.4e-05 22.1 1.4 8.7e-05 21.5 1.4 1.3 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family Steroid_dh PF02544.16 OQS05406.1 - 5.7e-05 23.1 0.6 0.0001 22.3 0.6 1.5 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase PEMT PF04191.13 OQS05406.1 - 0.0043 17.4 3.5 0.0092 16.4 2.1 2.2 2 1 0 2 2 2 1 Phospholipid methyltransferase DUF4213 PF13938.6 OQS05407.1 - 0.14 12.4 0.3 0.39 11.0 0.2 1.7 2 0 0 2 2 2 0 Putative heavy-metal chelation Gryzun-like PF12742.7 OQS05408.1 - 0.18 11.8 0.0 0.37 10.8 0.0 1.5 1 0 0 1 1 1 0 Gryzun, putative Golgi trafficking FANCF PF11107.8 OQS05409.1 - 0.0013 18.0 6.8 0.0041 16.4 6.8 1.8 1 1 0 1 1 1 1 Fanconi anemia group F protein (FANCF) ARID PF01388.21 OQS05410.1 - 0.02 15.6 4.7 4.2 8.1 0.0 4.1 2 2 2 4 4 4 0 ARID/BRIGHT DNA binding domain DUF1235 PF06822.12 OQS05410.1 - 0.023 14.0 0.0 0.26 10.6 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1235) Glyoxalase_2 PF12681.7 OQS05410.1 - 0.067 13.1 0.9 0.9 9.5 0.0 2.6 2 0 0 2 2 2 0 Glyoxalase-like domain IATP PF04568.12 OQS05410.1 - 0.094 13.1 7.1 2.5 8.6 1.1 2.8 2 0 0 2 2 2 0 Mitochondrial ATPase inhibitor, IATP Uds1 PF15456.6 OQS05410.1 - 1 9.6 8.9 1.4 9.1 0.9 2.5 2 0 0 2 2 2 0 Up-regulated During Septation zf-C4H2 PF10146.9 OQS05410.1 - 1 9.6 12.0 0.021 15.1 3.7 2.2 2 0 0 2 2 2 0 Zinc finger-containing protein DUF2481 PF10654.9 OQS05410.1 - 1.8 8.6 8.3 5.1 7.1 0.4 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2481) His_Phos_1 PF00300.22 OQS05411.1 - 1.3e-47 162.0 0.2 1.4e-47 161.9 0.2 1.0 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) RNase_Zc3h12a PF11977.8 OQS05412.1 - 1.9e-18 66.7 0.1 3.6e-18 65.8 0.1 1.4 1 0 0 1 1 1 1 Zc3h12a-like Ribonuclease NYN domain PRORP PF16953.5 OQS05412.1 - 1e-05 25.2 0.3 2.5e-05 23.9 0.3 1.7 1 0 0 1 1 1 1 Protein-only RNase P HemX PF04375.14 OQS05412.1 - 0.00036 19.9 0.5 0.00059 19.2 0.5 1.3 1 0 0 1 1 1 1 HemX, putative uroporphyrinogen-III C-methyltransferase DUF5068 PF16781.5 OQS05412.1 - 0.0043 16.8 0.0 0.0075 16.1 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF5068) F-112 PF09645.10 OQS05412.1 - 0.027 14.6 2.9 0.045 13.9 0.2 2.3 2 0 0 2 2 2 0 F-112 protein DUF4196 PF13846.6 OQS05412.1 - 3.7 7.8 8.5 0.68 10.1 0.8 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4196) V-ATPase_H_N PF03224.14 OQS05413.1 - 3.8e-45 154.5 0.0 5.9e-44 150.6 0.0 2.0 2 0 0 2 2 2 1 V-ATPase subunit H V-ATPase_H_C PF11698.8 OQS05413.1 - 5.9e-40 136.0 1.6 6.2e-38 129.5 0.4 2.7 2 1 0 2 2 2 1 V-ATPase subunit H Arm PF00514.23 OQS05413.1 - 2e-09 37.1 1.9 0.095 12.8 0.1 5.5 6 0 0 6 6 6 3 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 OQS05413.1 - 3.4e-06 27.4 0.6 0.096 13.1 0.0 3.9 3 2 0 3 3 3 2 HEAT repeats DRIM PF07539.12 OQS05413.1 - 0.00028 19.3 0.7 0.0056 15.1 0.0 2.6 2 1 0 2 2 2 1 Down-regulated in metastasis HEAT PF02985.22 OQS05413.1 - 0.0011 19.0 2.1 9.6 6.8 0.0 5.1 6 0 0 6 6 6 1 HEAT repeat Arm_2 PF04826.13 OQS05413.1 - 0.075 12.5 0.0 0.28 10.6 0.0 1.8 2 0 0 2 2 2 0 Armadillo-like NopRA1 PF16201.5 OQS05413.1 - 0.11 12.1 0.9 1.5 8.3 0.0 2.9 2 1 1 3 3 3 0 Nucleolar pre-ribosomal-associated protein 1 HEAT_EZ PF13513.6 OQS05413.1 - 0.19 12.3 3.0 36 5.0 0.0 4.3 4 0 0 4 4 4 0 HEAT-like repeat COG4 PF08318.12 OQS05416.1 - 8.6e-13 48.1 7.6 2.2e-12 46.7 2.0 3.1 1 1 1 2 2 2 1 COG4 transport protein RINT1_TIP1 PF04437.13 OQS05416.1 - 4.3e-07 29.2 2.8 4.3e-07 29.2 2.8 2.0 3 0 0 3 3 3 1 RINT-1 / TIP-1 family DUF3861 PF12977.7 OQS05416.1 - 0.029 14.5 0.5 15 5.8 0.0 3.7 3 0 0 3 3 3 0 Domain of Unknown Function with PDB structure (DUF3861) Heme_oxygenase PF01126.20 OQS05418.1 - 3.9e-62 209.7 3.2 3.9e-62 209.7 3.2 1.5 2 0 0 2 2 2 1 Heme oxygenase MFS_2 PF13347.6 OQS05419.1 - 8.1e-12 44.4 5.7 8.1e-12 44.4 5.7 2.4 2 1 0 2 2 2 2 MFS/sugar transport protein MFS_4 PF06779.14 OQS05419.1 - 5.2e-05 22.7 9.2 5.2e-05 22.7 9.2 1.9 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB Abhydrolase_1 PF00561.20 OQS05420.1 - 3.7e-09 36.6 0.1 7.2e-09 35.7 0.1 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Pox_A14 PF05767.12 OQS05420.1 - 0.046 13.9 0.0 0.11 12.6 0.0 1.6 1 0 0 1 1 1 0 Poxvirus virion envelope protein A14 Ank_2 PF12796.7 OQS05421.1 - 4e-09 36.9 3.5 3.7e-05 24.2 0.5 2.7 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQS05421.1 - 1.5e-08 35.0 4.7 0.0031 18.0 0.1 3.1 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQS05421.1 - 9.2e-06 25.6 0.4 2.9 8.8 0.0 4.2 3 1 1 4 4 4 2 Ankyrin repeat Ank_5 PF13857.6 OQS05421.1 - 0.0047 17.2 0.8 3.9 7.9 0.0 3.2 2 1 1 3 3 3 1 Ankyrin repeats (many copies) DUF3447 PF11929.8 OQS05421.1 - 0.18 11.8 2.6 2.1 8.3 0.2 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF3447) Tweety PF04906.13 OQS05422.1 - 1.6e-15 56.7 2.0 2.8e-15 55.9 2.0 1.2 1 0 0 1 1 1 1 Tweety SIT PF15330.6 OQS05422.1 - 0.31 11.5 3.1 1 9.8 0.3 2.8 3 0 0 3 3 3 0 SHP2-interacting transmembrane adaptor protein, SIT DUF2207 PF09972.9 OQS05422.1 - 0.82 8.4 2.9 6 5.5 0.2 2.7 3 0 0 3 3 3 0 Predicted membrane protein (DUF2207) CLASP_N PF12348.8 OQS05423.1 - 2.2e-25 89.6 1.7 4.6e-25 88.5 0.1 2.4 2 0 0 2 2 2 1 CLASP N terminal Fib_alpha PF08702.10 OQS05423.1 - 0.00035 20.8 6.9 0.00035 20.8 6.9 8.1 2 2 6 10 10 10 3 Fibrinogen alpha/beta chain family ZapB PF06005.12 OQS05423.1 - 0.01 16.2 4.5 0.01 16.2 4.5 11.4 4 3 3 7 7 7 0 Cell division protein ZapB Tropomyosin_1 PF12718.7 OQS05423.1 - 0.011 15.9 10.0 0.011 15.9 10.0 9.0 4 2 5 9 9 9 0 Tropomyosin like Glyco_transf_22 PF03901.17 OQS05424.1 - 1.3e-45 156.4 32.5 1.7e-45 156.0 32.5 1.0 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family CDP-OH_P_transf PF01066.21 OQS05425.1 - 1.2e-17 64.4 0.1 1.2e-17 64.4 0.1 2.7 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase SAC3_GANP PF03399.16 OQS05426.1 - 2.4e-20 73.1 1.2 1.3e-18 67.4 1.2 2.3 1 1 0 1 1 1 1 SAC3/GANP family CSN8_PSD8_EIF3K PF10075.9 OQS05426.1 - 2e-05 24.6 0.0 5.9e-05 23.1 0.0 1.7 2 0 0 2 2 2 1 CSN8/PSMD8/EIF3K family Zn_ribbon_recom PF13408.6 OQS05426.1 - 0.2 12.2 0.8 0.46 11.0 0.8 1.5 1 0 0 1 1 1 0 Recombinase zinc beta ribbon domain Ceramidase PF05875.12 OQS05427.1 - 1.6e-40 139.2 15.0 2.6e-40 138.5 15.0 1.2 1 0 0 1 1 1 1 Ceramidase Cauli_VI PF01693.16 OQS05428.1 - 6.6e-30 103.1 12.6 8.4e-15 54.8 2.0 2.6 2 0 0 2 2 2 2 Caulimovirus viroplasmin RNase_H PF00075.24 OQS05428.1 - 1.2e-26 93.6 0.4 2.2e-26 92.8 0.4 1.4 1 0 0 1 1 1 1 RNase H DUF832 PF05734.11 OQS05428.1 - 0.051 13.0 0.0 0.079 12.4 0.0 1.2 1 0 0 1 1 1 0 Herpesvirus protein of unknown function (DUF832) DUF3783 PF12646.7 OQS05428.1 - 0.15 12.0 0.1 4 7.5 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3783) Acyltransferase PF01553.21 OQS05429.1 - 1e-18 67.2 0.0 1.9e-18 66.4 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase CCD PF07860.11 OQS05429.1 - 0.13 12.3 0.0 5.5 7.1 0.0 2.4 2 0 0 2 2 2 0 WisP family C-Terminal Region RNase_H PF00075.24 OQS05430.1 - 6.1e-13 49.2 1.0 6.8e-13 49.0 1.0 1.0 1 0 0 1 1 1 1 RNase H Ank_5 PF13857.6 OQS05431.1 - 2.7e-09 37.1 1.1 0.0015 18.8 0.0 2.2 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 OQS05431.1 - 2.3e-08 34.5 1.6 0.0035 17.9 0.1 2.2 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OQS05431.1 - 7.5e-07 29.0 0.7 0.23 12.1 0.0 3.7 3 1 1 4 4 4 2 Ankyrin repeat Ank_4 PF13637.6 OQS05431.1 - 2.3e-06 28.0 1.6 0.037 14.6 0.5 2.5 2 1 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 OQS05431.1 - 0.033 14.6 0.5 13 6.4 0.0 2.7 2 1 0 2 2 2 0 Ankyrin repeat Peptidase_M4_C PF02868.15 OQS05431.1 - 0.088 12.7 0.1 0.14 12.0 0.1 1.4 1 0 0 1 1 1 0 Thermolysin metallopeptidase, alpha-helical domain FHA PF00498.26 OQS05432.1 - 6.1e-14 52.1 0.5 1.9e-13 50.6 0.1 2.1 2 0 0 2 2 2 1 FHA domain Yop-YscD_cpl PF16697.5 OQS05432.1 - 3.5e-05 24.0 0.3 0.00022 21.5 0.0 2.5 2 0 0 2 2 2 1 Inner membrane component of T3SS, cytoplasmic domain DHR10 PF18595.1 OQS05432.1 - 0.15 12.2 41.4 1.3 9.1 20.9 2.5 1 1 1 2 2 2 0 Designed helical repeat protein 10 domain ATG16 PF08614.11 OQS05432.1 - 2.2 8.5 43.7 1.4 9.2 19.4 3.0 2 1 1 3 3 3 0 Autophagy protein 16 (ATG16) RNase_H PF00075.24 OQS05433.1 - 1.9e-27 96.2 0.5 2.5e-27 95.8 0.5 1.1 1 0 0 1 1 1 1 RNase H RWD PF05773.22 OQS05434.1 - 0.48 10.7 2.4 1.1 9.5 2.4 1.7 1 1 0 1 1 1 0 RWD domain V-SNARE_C PF12352.8 OQS05435.1 - 2.7e-05 24.4 1.2 3.6e-05 23.9 1.2 1.2 1 0 0 1 1 1 1 Snare region anchored in the vesicle membrane C-terminus Drf_GBD PF06371.13 OQS05435.1 - 0.0086 15.7 0.1 0.01 15.4 0.1 1.0 1 0 0 1 1 1 1 Diaphanous GTPase-binding Domain SNARE PF05739.19 OQS05435.1 - 0.017 15.1 3.5 0.23 11.5 0.4 2.3 2 0 0 2 2 2 0 SNARE domain BST2 PF16716.5 OQS05435.1 - 0.036 14.6 0.8 0.048 14.2 0.8 1.1 1 0 0 1 1 1 0 Bone marrow stromal antigen 2 Misat_Tub_SegII PF10644.9 OQS05435.1 - 0.072 13.4 0.2 0.092 13.1 0.2 1.1 1 0 0 1 1 1 0 Misato Segment II tubulin-like domain Flagellin_C PF00700.21 OQS05435.1 - 0.079 13.3 0.6 0.11 12.9 0.6 1.2 1 0 0 1 1 1 0 Bacterial flagellin C-terminal helical region Ig_mannosidase PF17753.1 OQS05435.1 - 0.12 12.1 0.0 0.16 11.7 0.0 1.3 1 0 0 1 1 1 0 Ig-fold domain Laterosporulin PF17861.1 OQS05437.1 - 0.0052 17.2 0.1 0.011 16.1 0.1 1.5 1 0 0 1 1 1 1 Laterosporulin defensin-like peptide DZR PF12773.7 OQS05437.1 - 0.28 11.2 5.0 0.15 12.1 2.2 1.9 2 0 0 2 2 2 0 Double zinc ribbon zf-RING_2 PF13639.6 OQS05437.1 - 3.4 8.1 7.6 14 6.1 0.1 3.2 3 0 0 3 3 3 0 Ring finger domain Pkinase PF00069.25 OQS05439.1 - 2e-53 181.5 0.0 4.6e-32 111.4 0.0 3.0 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OQS05439.1 - 1.7e-52 178.3 0.0 3.4e-31 108.5 0.0 3.1 2 1 0 2 2 2 2 Protein tyrosine kinase Ank_3 PF13606.6 OQS05439.1 - 0.0031 17.9 0.1 0.022 15.3 0.0 2.5 2 0 0 2 2 2 1 Ankyrin repeat Ank_4 PF13637.6 OQS05439.1 - 0.0062 17.1 0.1 0.016 15.8 0.1 1.7 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 OQS05439.1 - 0.0078 16.8 0.0 0.016 15.8 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 OQS05439.1 - 0.0081 16.6 0.6 0.29 11.6 0.1 2.8 2 0 0 2 2 2 1 Ankyrin repeat Ank_5 PF13857.6 OQS05439.1 - 0.028 14.7 0.1 0.062 13.6 0.1 1.6 1 0 0 1 1 1 0 Ankyrin repeats (many copies) Haspin_kinase PF12330.8 OQS05439.1 - 0.042 12.8 2.2 1.7 7.5 0.0 2.6 3 0 0 3 3 3 0 Haspin like kinase domain PX PF00787.24 OQS05440.1 - 9.1e-09 35.3 0.1 1.7e-08 34.4 0.0 1.6 1 1 0 1 1 1 1 PX domain FtsX PF02687.21 OQS05441.1 - 2.2 8.8 0.0 2.2 8.8 0.0 3.0 2 1 0 2 2 2 0 FtsX-like permease family Ank_2 PF12796.7 OQS05444.1 - 1.3e-18 67.3 10.4 2.4e-06 28.0 0.5 5.4 1 1 6 7 7 7 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQS05444.1 - 2.6e-12 47.0 7.4 0.0081 16.7 0.1 6.9 5 1 1 6 6 6 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 OQS05444.1 - 1.1e-10 41.5 7.5 0.52 10.7 0.0 8.5 4 3 4 8 8 8 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQS05444.1 - 7.5e-07 29.0 10.5 14 6.6 0.0 8.9 9 0 0 9 9 9 1 Ankyrin repeat Ank PF00023.30 OQS05444.1 - 0.41 11.2 3.5 2.6e+02 2.3 0.0 5.4 3 2 1 4 4 4 0 Ankyrin repeat CpeT PF06206.11 OQS05445.1 - 0.091 12.7 0.0 0.12 12.4 0.0 1.3 1 1 0 1 1 1 0 CpeT/CpcT family (DUF1001) bZIP_1 PF00170.21 OQS05446.1 - 0.0013 18.8 7.8 0.0013 18.8 7.8 2.2 2 0 0 2 2 2 1 bZIP transcription factor DNA_pol_B_3 PF08408.10 OQS05446.1 - 0.058 13.6 0.0 0.11 12.7 0.0 1.4 1 0 0 1 1 1 0 DNA polymerase family B viral insert Prominin PF05478.11 OQS05446.1 - 0.15 10.0 1.5 0.23 9.3 1.5 1.2 1 0 0 1 1 1 0 Prominin bZIP_Maf PF03131.17 OQS05446.1 - 0.16 12.5 11.8 0.14 12.7 10.1 1.8 1 1 0 1 1 1 0 bZIP Maf transcription factor Macoilin PF09726.9 OQS05446.1 - 2 6.8 9.1 2.9 6.4 9.1 1.1 1 0 0 1 1 1 0 Macoilin family SR-25 PF10500.9 OQS05446.1 - 2.1 7.9 18.9 3.3 7.3 18.9 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein FapA PF03961.13 OQS05446.1 - 2.9 6.4 4.8 4.1 5.9 4.8 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A HR1 PF02185.16 OQS05446.1 - 3.9 7.6 12.1 1.7 8.8 5.7 2.3 2 0 0 2 2 2 0 Hr1 repeat Proteasome PF00227.26 OQS05447.1 - 2.9e-29 101.9 0.0 3.5e-29 101.7 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit DUF5050 PF16472.5 OQS05448.1 - 3.5e-06 26.5 0.7 0.00074 18.8 0.1 2.5 1 1 1 2 2 2 2 Domain of unknown function (DUF5050) Ldl_recept_b PF00058.17 OQS05448.1 - 0.00013 22.4 4.5 2.1 8.9 0.2 4.6 5 0 0 5 5 5 3 Low-density lipoprotein receptor repeat class B Str_synth PF03088.16 OQS05448.1 - 0.0058 16.7 0.0 18 5.5 0.0 3.8 2 1 2 4 4 4 1 Strictosidine synthase DEAD PF00270.29 OQS05449.1 - 1.2e-45 155.4 0.1 3.8e-45 153.8 0.1 1.9 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OQS05449.1 - 7.4e-31 106.8 4.0 7.5e-30 103.5 0.1 3.5 3 0 0 3 3 3 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 OQS05449.1 - 0.017 15.4 0.0 0.077 13.3 0.0 2.2 1 0 0 1 1 1 0 AAA domain WBS_methylT PF12589.8 OQS05450.1 - 2.1e-18 66.8 3.2 2.1e-18 66.8 3.2 1.6 2 0 0 2 2 1 1 Methyltransferase involved in Williams-Beuren syndrome Methyltransf_25 PF13649.6 OQS05450.1 - 1e-10 42.2 0.0 2.2e-10 41.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OQS05450.1 - 1.4e-10 41.7 0.0 2.5e-10 40.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OQS05450.1 - 5.5e-06 27.0 0.4 0.00045 20.9 0.0 2.8 2 1 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 OQS05450.1 - 0.00052 19.4 0.0 0.00077 18.9 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.6 OQS05450.1 - 0.0012 18.6 0.0 0.0017 18.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OQS05450.1 - 0.0016 18.3 0.0 0.004 17.0 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 OQS05450.1 - 0.0022 17.5 0.1 0.0043 16.6 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase small domain CMAS PF02353.20 OQS05450.1 - 0.019 14.2 0.0 0.088 12.1 0.0 1.8 1 1 0 1 1 1 0 Mycolic acid cyclopropane synthetase PCMT PF01135.19 OQS05450.1 - 0.05 13.4 0.0 0.077 12.7 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) PrmA PF06325.13 OQS05450.1 - 0.13 11.6 0.0 0.74 9.1 0.1 1.9 2 0 0 2 2 2 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_32 PF13679.6 OQS05450.1 - 0.16 12.0 0.1 0.4 10.7 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain Thioredoxin PF00085.20 OQS05451.1 - 6.2e-31 106.4 0.1 1.3e-30 105.4 0.1 1.6 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_6 PF13848.6 OQS05451.1 - 1.4e-06 28.3 0.0 7.2e-06 26.0 0.0 2.1 2 1 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_2 PF13098.6 OQS05451.1 - 1.9e-05 25.1 0.2 9.8e-05 22.8 0.2 2.2 1 1 0 1 1 1 1 Thioredoxin-like domain OST3_OST6 PF04756.13 OQS05451.1 - 0.00039 19.9 0.0 0.0008 18.8 0.0 1.4 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_8 PF13905.6 OQS05451.1 - 0.011 16.1 0.0 0.83 10.0 0.0 3.3 2 1 1 3 3 3 0 Thioredoxin-like DUF1506 PF07405.11 OQS05452.1 - 0.026 14.7 0.1 0.039 14.1 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1506) Tnp_P_element PF12017.8 OQS05452.1 - 0.03 13.8 0.4 0.034 13.6 0.4 1.1 1 0 0 1 1 1 0 Transposase protein DNA_topoisoIV PF00521.20 OQS05453.1 - 0.0077 15.2 4.9 0.014 14.3 4.9 1.4 1 0 0 1 1 1 1 DNA gyrase/topoisomerase IV, subunit A PhaP_Bmeg PF09602.10 OQS05453.1 - 0.026 14.5 1.8 0.051 13.5 1.8 1.5 1 0 0 1 1 1 0 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) Spectrin PF00435.21 OQS05453.1 - 0.36 11.3 6.2 1.3 9.5 5.0 2.4 1 1 0 1 1 1 0 Spectrin repeat Metallophos PF00149.28 OQS05454.1 - 9.9e-25 88.2 0.1 1.8e-24 87.4 0.1 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Ion_trans PF00520.31 OQS05455.1 - 1.5e-37 129.2 64.7 2.3e-23 82.7 21.5 3.4 3 1 0 3 3 3 3 Ion transport protein NanE PF04131.14 OQS05455.1 - 0.066 12.4 0.0 8.2 5.6 0.0 2.4 2 0 0 2 2 2 0 Putative N-acetylmannosamine-6-phosphate epimerase Ion_trans PF00520.31 OQS05456.1 - 2.6e-05 23.6 2.1 3.3e-05 23.2 2.1 1.1 1 0 0 1 1 1 1 Ion transport protein NAD_binding_5 PF07994.12 OQS05457.1 - 7e-143 475.8 0.0 1e-142 475.3 0.0 1.3 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase Alpha_kinase PF02816.18 OQS05457.1 - 2.8e-54 184.1 0.1 3e-53 180.7 0.0 2.5 3 0 0 3 3 3 1 Alpha-kinase family Inos-1-P_synth PF01658.17 OQS05457.1 - 1.9e-47 160.0 0.3 5e-47 158.7 0.3 1.8 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase Vps39_2 PF10367.9 OQS05457.1 - 3.8e-25 88.5 0.1 1.5e-24 86.6 0.1 2.1 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 CNH PF00780.22 OQS05457.1 - 1e-20 74.5 0.2 2e-20 73.6 0.0 1.6 2 0 0 2 2 2 1 CNH domain Vps39_1 PF10366.9 OQS05457.1 - 9.6e-06 25.8 0.0 9.6e-06 25.8 0.0 3.2 5 0 0 5 5 2 1 Vacuolar sorting protein 39 domain 1 SHOCT PF09851.9 OQS05457.1 - 0.00066 19.3 0.2 0.0014 18.3 0.2 1.6 1 0 0 1 1 1 1 Short C-terminal domain Clathrin PF00637.20 OQS05457.1 - 0.0012 18.7 0.0 2 8.3 0.0 3.1 3 0 0 3 3 3 2 Region in Clathrin and VPS WD40_like PF17005.5 OQS05457.1 - 0.009 15.4 0.0 0.03 13.6 0.0 1.8 1 1 0 1 1 1 1 WD40-like domain GvpG PF05120.12 OQS05457.1 - 0.028 14.4 0.8 0.072 13.1 0.8 1.6 1 0 0 1 1 1 0 Gas vesicle protein G TPR_2 PF07719.17 OQS05457.1 - 0.18 12.0 0.5 32 5.0 0.4 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat DMAP_binding PF06464.11 OQS05457.1 - 0.34 11.8 2.5 1.2 10.0 0.1 2.6 2 0 0 2 2 2 0 DMAP1-binding Domain zf-HC5HC2H PF13771.6 OQS05457.1 - 0.47 10.7 2.1 0.52 10.6 0.2 2.0 2 0 0 2 2 2 0 PHD-like zinc-binding domain TPR_16 PF13432.6 OQS05457.1 - 0.89 10.3 3.8 2.1 9.0 0.0 3.1 4 0 0 4 4 2 0 Tetratricopeptide repeat ABC_tran PF00005.27 OQS05458.1 - 3.1e-21 76.3 0.0 7.8e-21 75.0 0.0 1.7 1 0 0 1 1 1 1 ABC transporter ABC_tran_Xtn PF12848.7 OQS05458.1 - 1e-12 47.9 2.4 8.8e-11 41.7 2.4 2.2 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.6 OQS05458.1 - 3.5e-12 46.7 0.6 4.5e-05 23.4 0.1 2.2 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 OQS05458.1 - 7.5e-06 25.5 0.5 0.039 13.4 0.0 2.2 1 1 1 2 2 2 2 RecF/RecN/SMC N terminal domain DUF3584 PF12128.8 OQS05458.1 - 0.00082 17.0 0.1 0.0013 16.4 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) AAA_23 PF13476.6 OQS05458.1 - 0.00089 19.8 0.1 0.00089 19.8 0.1 1.9 2 1 0 2 2 2 1 AAA domain AAA_29 PF13555.6 OQS05458.1 - 0.0017 18.0 0.1 0.0035 17.1 0.1 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.6 OQS05458.1 - 0.0021 18.3 0.0 0.0043 17.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.23 OQS05458.1 - 0.0054 16.8 0.0 0.013 15.5 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_13 PF13166.6 OQS05458.1 - 0.0066 15.2 0.7 1 7.9 0.0 2.9 3 0 0 3 3 3 1 AAA domain AAA_15 PF13175.6 OQS05458.1 - 0.0088 15.8 0.0 0.02 14.6 0.0 1.6 2 0 0 2 2 2 1 AAA ATPase domain RsgA_GTPase PF03193.16 OQS05458.1 - 0.017 15.0 0.3 0.035 14.0 0.0 1.6 2 0 0 2 2 2 0 RsgA GTPase NACHT PF05729.12 OQS05458.1 - 0.025 14.5 0.1 0.067 13.1 0.0 1.8 2 0 0 2 2 2 0 NACHT domain Dynamin_N PF00350.23 OQS05458.1 - 0.033 14.3 0.1 0.25 11.4 0.0 2.2 2 0 0 2 2 2 0 Dynamin family FeoB_N PF02421.18 OQS05458.1 - 0.037 13.6 0.0 0.06 12.9 0.0 1.3 1 0 0 1 1 1 0 Ferrous iron transport protein B AAA_28 PF13521.6 OQS05458.1 - 0.039 14.2 0.0 0.07 13.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 OQS05458.1 - 0.044 13.5 0.8 0.7 9.6 0.1 2.5 2 1 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 OQS05458.1 - 0.047 13.6 0.0 0.076 12.9 0.0 1.4 1 0 0 1 1 1 0 NTPase AAA_25 PF13481.6 OQS05458.1 - 0.049 13.2 0.0 0.33 10.5 0.0 2.0 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.22 OQS05458.1 - 0.064 12.4 0.0 0.13 11.4 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain AAA_16 PF13191.6 OQS05458.1 - 0.1 13.0 0.1 0.21 12.0 0.0 1.6 1 1 0 1 1 1 0 AAA ATPase domain PhetRS_B1 PF18262.1 OQS05458.1 - 0.1 12.8 0.0 0.26 11.5 0.0 1.7 1 0 0 1 1 1 0 Phe-tRNA synthetase beta subunit B1 domain Zeta_toxin PF06414.12 OQS05458.1 - 0.17 11.1 0.3 0.37 10.0 0.0 1.6 2 0 0 2 2 2 0 Zeta toxin cobW PF02492.19 OQS05458.1 - 0.18 11.4 0.1 0.32 10.6 0.1 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain Ion_trans PF00520.31 OQS05459.1 - 7.4e-05 22.1 1.6 0.00044 19.5 0.2 2.0 2 0 0 2 2 2 2 Ion transport protein Beta_elim_lyase PF01212.21 OQS05460.1 - 1e-49 169.4 0.0 2.7e-30 105.7 0.0 2.2 1 1 1 2 2 2 2 Beta-eliminating lyase LRR_9 PF14580.6 OQS05460.1 - 6.8e-08 32.2 0.1 1.6e-07 31.0 0.1 1.5 1 0 0 1 1 1 1 Leucine-rich repeat LRR_8 PF13855.6 OQS05460.1 - 0.00041 20.0 8.6 0.0028 17.4 2.6 2.5 1 1 2 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 OQS05460.1 - 0.0009 19.6 6.8 0.05 14.0 0.3 3.7 1 1 4 5 5 5 4 Leucine Rich repeats (2 copies) IQ PF00612.27 OQS05460.1 - 0.0033 17.1 25.5 0.095 12.5 1.9 4.8 4 0 0 4 4 4 3 IQ calmodulin-binding motif DegT_DnrJ_EryC1 PF01041.17 OQS05460.1 - 0.17 11.2 0.0 0.37 10.0 0.0 1.5 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family 2OG-FeII_Oxy PF03171.20 OQS05461.1 - 9.2e-07 29.3 0.0 1.8e-06 28.3 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily zf-C2H2_3rep PF18868.1 OQS05462.1 - 0.57 10.9 8.8 0.11 13.2 0.6 3.0 2 1 0 3 3 3 0 Zinc finger C2H2-type, 3 repeats AF-4 PF05110.13 OQS05464.1 - 0.041 12.0 37.5 0.055 11.6 37.5 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein TruD PF01142.18 OQS05466.1 - 4.4e-68 230.0 0.0 7.6e-61 206.2 0.0 3.2 3 0 0 3 3 3 3 tRNA pseudouridine synthase D (TruD) Brix PF04427.18 OQS05467.1 - 4.2e-44 151.0 0.2 6.6e-44 150.3 0.2 1.3 1 0 0 1 1 1 1 Brix domain Taxilin PF09728.9 OQS05468.1 - 6.7e-68 229.1 42.9 1e-67 228.6 42.9 1.3 1 0 0 1 1 1 1 Myosin-like coiled-coil protein K_oxygenase PF13434.6 OQS05468.1 - 3.1e-12 46.3 0.0 3.1e-12 46.3 0.0 2.4 2 1 1 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 OQS05468.1 - 4.2e-10 39.3 0.0 1.3e-06 27.9 0.0 3.2 4 0 0 4 4 4 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 OQS05468.1 - 2.4e-07 30.3 0.2 5.7e-05 22.5 0.0 2.9 2 1 1 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 OQS05468.1 - 0.00014 21.8 0.6 0.64 10.0 0.0 3.8 5 0 0 5 5 5 2 FAD-NAD(P)-binding YgbB PF02542.16 OQS05468.1 - 0.095 13.0 6.0 0.1 12.9 1.5 3.1 2 1 1 3 3 3 0 YgbB family Pyr_redox PF00070.27 OQS05468.1 - 0.12 12.9 0.0 0.44 11.1 0.0 2.0 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DUF4201 PF13870.6 OQS05468.1 - 0.76 9.5 37.0 0.34 10.6 7.5 3.6 2 1 1 3 3 3 0 Domain of unknown function (DUF4201) GIT_CC PF16559.5 OQS05468.1 - 1.1 9.2 10.6 5.3 7.0 0.8 3.9 4 0 0 4 4 4 0 GIT coiled-coil Rho guanine nucleotide exchange factor Fib_alpha PF08702.10 OQS05468.1 - 5.3 7.2 32.6 4.7 7.4 9.0 4.0 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family TSC22 PF01166.18 OQS05468.1 - 6.1 7.2 8.5 4.4 7.7 0.1 3.8 3 1 0 3 3 3 0 TSC-22/dip/bun family TBCC PF07986.12 OQS05469.1 - 0.0012 18.5 0.0 0.0025 17.6 0.0 1.4 1 0 0 1 1 1 1 Tubulin binding cofactor C NHL PF01436.21 OQS05472.1 - 1e-31 107.3 12.2 3.1e-07 30.1 0.2 6.8 7 0 0 7 7 7 6 NHL repeat DUF5094 PF17015.5 OQS05472.1 - 0.024 14.7 3.1 0.038 14.1 3.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5094) PRKG1_interact PF15898.5 OQS05472.1 - 0.029 15.3 4.9 0.051 14.5 4.9 1.3 1 0 0 1 1 1 0 cGMP-dependent protein kinase interacting domain SLD3 PF08639.10 OQS05472.1 - 0.23 10.2 3.6 0.29 9.8 3.6 1.1 1 0 0 1 1 1 0 DNA replication regulator SLD3 NYD-SP28_assoc PF14775.6 OQS05472.1 - 0.83 9.8 6.7 1.4 9.1 6.7 1.3 1 0 0 1 1 1 0 Sperm tail C-terminal domain LRS4 PF10422.9 OQS05472.1 - 2 7.9 9.2 3.8 7.0 9.2 1.3 1 0 0 1 1 1 0 Monopolin complex subunit LRS4 DivIC PF04977.15 OQS05472.1 - 2.1 8.2 7.9 4.3 7.2 7.9 1.5 1 0 0 1 1 1 0 Septum formation initiator TMEM70 PF06979.12 OQS05473.1 - 3.4e-36 124.5 0.5 4.3e-36 124.2 0.5 1.1 1 0 0 1 1 1 1 Assembly, mitochondrial proton-transport ATP synth complex zf-CW PF07496.15 OQS05474.1 - 0.009 16.0 0.7 0.009 16.0 0.7 2.7 2 0 0 2 2 2 1 CW-type Zinc Finger PsbP PF01789.16 OQS05474.1 - 0.1 12.7 0.1 0.23 11.6 0.1 1.5 1 0 0 1 1 1 0 PsbP DUF21 PF01595.20 OQS05475.1 - 8.7e-38 129.8 1.1 1.3e-37 129.2 1.1 1.3 1 0 0 1 1 1 1 Cyclin M transmembrane N-terminal domain CBS PF00571.28 OQS05475.1 - 3.4e-09 37.0 0.1 0.00011 22.6 0.0 2.6 2 0 0 2 2 2 2 CBS domain cNMP_binding PF00027.29 OQS05475.1 - 0.0021 18.1 0.0 0.0044 17.0 0.0 1.5 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain TRF PF08558.10 OQS05475.1 - 0.0047 16.5 0.0 0.15 11.7 0.0 2.7 3 0 0 3 3 3 1 Telomere repeat binding factor (TRF) DUF21 PF01595.20 OQS05476.1 - 3.9e-35 121.1 4.1 8.8e-35 120.0 4.1 1.5 1 0 0 1 1 1 1 Cyclin M transmembrane N-terminal domain CBS PF00571.28 OQS05476.1 - 1.8e-10 41.1 0.2 0.001 19.5 0.1 2.6 2 0 0 2 2 2 2 CBS domain PHO4 PF01384.20 OQS05476.1 - 0.065 12.3 0.0 0.11 11.5 0.0 1.5 1 1 0 1 1 1 0 Phosphate transporter family ODV-E18 PF10717.9 OQS05477.1 - 2.3 8.1 6.3 0.25 11.3 0.9 2.2 2 0 0 2 2 2 0 Occlusion-derived virus envelope protein ODV-E18 Ribosomal_S3_C PF00189.20 OQS05478.1 - 1.1e-22 80.3 1.2 4.8e-22 78.3 1.7 1.8 2 0 0 2 2 2 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.17 OQS05478.1 - 3.6e-12 45.9 0.1 7.4e-12 44.9 0.1 1.6 1 0 0 1 1 1 1 KH domain Glyco_hydro_18 PF00704.28 OQS05479.1 - 2.2e-73 247.8 0.7 3.9e-73 246.9 0.7 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Ricin_B_lectin PF00652.22 OQS05479.1 - 9.9e-29 100.2 9.8 4.3e-14 52.9 0.7 2.4 2 0 0 2 2 2 2 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.6 OQS05479.1 - 3.3e-14 53.4 10.5 1.6e-07 32.0 1.0 2.9 2 0 0 2 2 2 2 Ricin-type beta-trefoil lectin domain-like CDtoxinA PF03498.14 OQS05479.1 - 0.00017 21.2 0.3 0.21 11.2 0.1 2.4 2 0 0 2 2 2 2 Cytolethal distending toxin A/C domain DUF3130 PF11328.8 OQS05479.1 - 0.066 13.5 0.1 6.6 7.0 0.0 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF3130 EMP70 PF02990.16 OQS05480.1 - 3.9e-212 705.5 12.6 5.3e-212 705.1 12.6 1.2 1 0 0 1 1 1 1 Endomembrane protein 70 ACAS_N PF16177.5 OQS05480.1 - 0.068 13.1 0.4 0.18 11.8 0.4 1.7 1 0 0 1 1 1 0 Acetyl-coenzyme A synthetase N-terminus GNAT_acetyltr_2 PF13718.6 OQS05481.1 - 6.6e-97 323.4 2.9 9.1e-97 322.9 0.0 2.4 2 1 0 2 2 2 1 GNAT acetyltransferase 2 tRNA_bind_2 PF13725.6 OQS05481.1 - 7.9e-72 241.7 3.7 7.9e-72 241.7 3.7 2.3 2 0 0 2 2 2 1 Possible tRNA binding domain Helicase_RecD PF05127.14 OQS05481.1 - 2.7e-60 203.2 0.0 7.5e-60 201.8 0.0 1.8 1 0 0 1 1 1 1 Helicase DUF1726 PF08351.11 OQS05481.1 - 4.4e-34 116.3 0.1 1.1e-33 115.0 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1726) AAA_22 PF13401.6 OQS05481.1 - 0.0039 17.5 0.0 0.29 11.4 0.0 3.0 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 OQS05481.1 - 0.25 11.7 2.3 3.4 8.0 0.2 3.4 3 1 0 3 3 3 0 AAA domain Ank_2 PF12796.7 OQS05483.1 - 3.7e-24 85.1 1.1 5.2e-11 43.0 0.5 2.9 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 OQS05483.1 - 4.6e-21 74.3 5.7 1.3e-06 28.6 0.1 4.6 5 0 0 5 5 5 4 Ankyrin repeat Ank_3 PF13606.6 OQS05483.1 - 1.8e-17 61.6 0.2 0.0021 18.4 0.0 4.4 4 0 0 4 4 4 3 Ankyrin repeat Ank_4 PF13637.6 OQS05483.1 - 3.9e-16 59.2 0.1 2.1e-05 25.0 0.0 3.4 3 0 0 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 OQS05483.1 - 7.3e-11 42.1 0.7 6.3e-05 23.2 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 OQS05485.1 - 6.4e-129 420.8 60.8 5.3e-18 65.4 2.3 10.1 1 1 10 11 11 11 11 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQS05485.1 - 3.7e-100 327.1 19.9 2e-11 44.2 0.1 14.7 3 2 12 15 15 15 15 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQS05485.1 - 8.6e-89 280.7 17.4 0.00027 21.1 0.0 18.3 18 0 0 18 18 18 17 Ankyrin repeat Ank PF00023.30 OQS05485.1 - 1.3e-83 272.0 49.1 8.9e-06 25.9 0.3 18.1 16 2 2 18 18 18 17 Ankyrin repeat Ank_5 PF13857.6 OQS05485.1 - 1.5e-79 261.0 25.4 1.4e-08 34.8 0.2 14.1 4 4 10 14 14 14 14 Ankyrin repeats (many copies) Kazal_2 PF07648.15 OQS05485.1 - 2.1e-24 85.4 34.8 1.1e-07 31.9 5.3 4.7 3 1 1 4 4 4 4 Kazal-type serine protease inhibitor domain Kazal_1 PF00050.21 OQS05485.1 - 4.4e-20 71.4 33.4 1.7e-07 31.1 2.6 4.7 3 1 1 4 4 4 4 Kazal-type serine protease inhibitor domain DUF4682 PF15733.5 OQS05485.1 - 0.22 12.1 2.6 31 5.2 0.0 3.4 3 1 1 4 4 4 0 Domain of unknown function (DUF4682) AviRa PF11599.8 OQS05485.1 - 0.29 10.6 1.8 11 5.4 0.2 2.4 2 0 0 2 2 2 0 RRNA methyltransferase AviRa GFO_IDH_MocA PF01408.22 OQS05486.1 - 2.4e-18 67.1 0.1 3.9e-18 66.4 0.1 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 OQS05486.1 - 1.4e-10 41.2 0.0 2.4e-10 40.4 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain NAD_binding_3 PF03447.16 OQS05486.1 - 0.00067 20.3 0.1 0.0011 19.5 0.1 1.4 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain Semialdhyde_dh PF01118.24 OQS05486.1 - 0.14 12.6 0.0 0.21 12.0 0.0 1.4 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain zf-TRAF_2 PF15965.5 OQS05488.1 - 0.00017 22.0 2.3 0.25 11.8 0.2 2.6 2 0 0 2 2 2 2 TRAF-like zinc-finger NTP_transf_2 PF01909.23 OQS05488.1 - 0.00034 20.8 0.0 0.0012 19.1 0.0 2.0 1 0 0 1 1 1 1 Nucleotidyltransferase domain PAP_assoc PF03828.19 OQS05488.1 - 0.0013 18.9 0.3 0.06 13.6 0.3 2.9 1 1 0 1 1 1 1 Cid1 family poly A polymerase PAM2 PF07145.15 OQS05488.1 - 0.028 14.1 0.3 0.076 12.7 0.3 1.8 1 0 0 1 1 1 0 Ataxin-2 C-terminal region zf-TRAF PF02176.18 OQS05488.1 - 0.14 12.9 3.8 4.4 8.1 0.5 2.8 2 0 0 2 2 2 0 TRAF-type zinc finger GFO_IDH_MocA PF01408.22 OQS05489.1 - 5.4e-27 95.0 0.2 1e-26 94.1 0.2 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 OQS05489.1 - 4.3e-08 33.2 0.0 7.9e-08 32.3 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain F420_oxidored PF03807.17 OQS05489.1 - 1.2e-06 29.0 0.1 3e-06 27.7 0.1 1.7 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.20 OQS05489.1 - 2.9e-05 24.2 0.1 5.1e-05 23.3 0.1 1.4 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase 2-Hacid_dh_C PF02826.19 OQS05489.1 - 0.00011 21.6 0.0 0.00018 20.9 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Sacchrp_dh_NADP PF03435.18 OQS05489.1 - 0.00038 20.7 0.2 0.0013 19.0 0.0 1.9 1 1 1 2 2 2 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_3 PF03447.16 OQS05489.1 - 0.0025 18.5 0.1 0.0041 17.8 0.1 1.4 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain Rossmann-like PF10727.9 OQS05489.1 - 0.0045 16.8 0.1 0.0077 16.1 0.1 1.5 1 0 0 1 1 1 1 Rossmann-like domain Gp_dh_N PF00044.24 OQS05489.1 - 0.0048 17.2 0.1 0.011 16.0 0.1 1.6 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain ThiF PF00899.21 OQS05489.1 - 0.0056 16.1 0.0 0.01 15.2 0.0 1.3 1 0 0 1 1 1 1 ThiF family XdhC_C PF13478.6 OQS05489.1 - 0.044 14.3 0.1 0.12 12.9 0.1 1.7 1 1 0 1 1 1 0 XdhC Rossmann domain DUF1582 PF07621.11 OQS05490.1 - 0.039 13.9 0.0 0.066 13.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1582) Lactonase PF10282.9 OQS05491.1 - 1.7e-67 228.1 0.5 2e-67 227.9 0.5 1.0 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller YmzC PF14157.6 OQS05491.1 - 0.0073 16.4 1.9 2 8.6 0.0 3.7 4 1 1 5 5 5 2 YmzC-like protein NHL PF01436.21 OQS05491.1 - 0.072 13.2 0.2 0.86 9.8 0.0 2.9 2 0 0 2 2 2 0 NHL repeat SGL PF08450.12 OQS05491.1 - 0.078 12.6 0.3 5.9 6.4 0.0 3.4 1 1 4 5 5 5 0 SMP-30/Gluconolactonase/LRE-like region FYVE PF01363.21 OQS05492.1 - 3.4e-14 52.7 8.9 7.1e-14 51.7 8.9 1.5 1 0 0 1 1 1 1 FYVE zinc finger NOB1_Zn_bind PF08772.11 OQS05492.1 - 0.68 10.1 7.8 0.9 9.7 5.9 2.0 2 0 0 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like FYVE_2 PF02318.16 OQS05492.1 - 0.77 10.0 9.0 2 8.6 9.0 1.7 1 1 0 1 1 1 0 FYVE-type zinc finger zf-piccolo PF05715.13 OQS05492.1 - 1 9.6 6.8 8.6 6.6 3.9 2.6 2 0 0 2 2 2 0 Piccolo Zn-finger SGT1 PF07093.11 OQS05493.1 - 1.9e-80 271.0 3.9 1.5e-75 254.9 1.3 2.0 1 1 1 2 2 2 2 SGT1 protein Mito_carr PF00153.27 OQS05494.1 - 4.6e-63 209.2 4.2 1.2e-20 73.2 0.0 3.0 2 1 1 3 3 3 3 Mitochondrial carrier protein Tim17 PF02466.19 OQS05494.1 - 0.016 15.6 2.3 6.1 7.3 0.8 3.4 3 1 0 3 3 3 0 Tim17/Tim22/Tim23/Pmp24 family TPR_12 PF13424.6 OQS05495.1 - 0.0035 17.6 0.2 0.0035 17.6 0.2 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat PQQ_2 PF13360.6 OQS05496.1 - 0.00011 21.9 0.0 0.052 13.1 0.0 2.9 1 1 1 2 2 2 2 PQQ-like domain SBBP PF06739.11 OQS05496.1 - 0.0074 16.3 1.5 0.0074 16.3 1.5 5.6 8 0 0 8 8 8 3 Beta-propeller repeat RNA_pol_A_bac PF01000.26 OQS05496.1 - 0.034 14.5 0.0 0.25 11.7 0.0 2.2 2 0 0 2 2 2 0 RNA polymerase Rpb3/RpoA insert domain PQQ_3 PF13570.6 OQS05496.1 - 0.053 14.0 0.2 20 5.8 0.0 4.2 5 0 0 5 5 5 0 PQQ-like domain UCR_UQCRX_QCR9 PF05365.12 OQS05497.1 - 2e-16 59.6 0.6 2.5e-16 59.3 0.6 1.1 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like NotI PF12183.8 OQS05497.1 - 0.075 12.4 0.0 0.082 12.2 0.0 1.0 1 0 0 1 1 1 0 Restriction endonuclease NotI PRA-CH PF01502.18 OQS05498.1 - 3.9e-24 84.3 0.2 8.9e-24 83.1 0.2 1.6 1 0 0 1 1 1 1 Phosphoribosyl-AMP cyclohydrolase PRA-PH PF01503.17 OQS05498.1 - 1.3e-13 51.2 0.6 2.6e-13 50.2 0.1 1.9 2 0 0 2 2 2 1 Phosphoribosyl-ATP pyrophosphohydrolase 2_5_RNA_ligase2 PF13563.6 OQS05498.1 - 0.00036 20.5 0.5 0.39 10.6 0.0 3.3 2 2 1 3 3 3 2 2'-5' RNA ligase superfamily Con-6 PF10346.9 OQS05498.1 - 0.066 13.3 0.1 0.14 12.3 0.1 1.5 1 0 0 1 1 1 0 Conidiation protein 6 MazG PF03819.17 OQS05498.1 - 0.068 13.4 0.0 0.15 12.2 0.0 1.5 1 0 0 1 1 1 0 MazG nucleotide pyrophosphohydrolase domain Ank_2 PF12796.7 OQS05499.1 - 1.3e-93 307.7 22.3 3.4e-15 56.4 0.1 8.5 1 1 7 9 9 9 9 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQS05499.1 - 1.6e-70 232.7 15.6 9.6e-09 35.6 0.0 12.1 8 4 3 12 12 12 12 Ankyrin repeats (many copies) Ank PF00023.30 OQS05499.1 - 2.1e-61 201.8 39.3 3.5e-05 24.0 0.1 16.3 15 1 1 16 16 16 15 Ankyrin repeat Ank_5 PF13857.6 OQS05499.1 - 9.2e-60 197.9 27.6 2.8e-07 30.7 0.5 14.5 3 2 12 15 15 15 15 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQS05499.1 - 1.6e-58 187.8 25.6 0.00024 21.3 0.0 16.6 17 0 0 17 17 17 14 Ankyrin repeat YfmQ PF10787.9 OQS05499.1 - 0.00057 19.7 0.0 10 5.9 0.0 5.8 6 1 1 7 7 7 1 Uncharacterised protein from bacillus cereus group ArlS_N PF18719.1 OQS05499.1 - 0.11 12.7 0.0 21 5.4 0.0 2.9 3 0 0 3 3 3 0 ArlS sensor domain DUF2384 PF09722.10 OQS05499.1 - 0.9 9.6 3.2 1.9e+02 2.2 0.0 4.5 6 0 0 6 6 6 0 Protein of unknown function (DUF2384) UQ_con PF00179.26 OQS05500.1 - 1.8e-43 147.5 0.0 2e-43 147.4 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 OQS05500.1 - 2.7e-06 27.1 0.0 3.4e-06 26.8 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B TPR_1 PF00515.28 OQS05501.1 - 8.2e-25 85.6 4.1 1.4e-07 31.0 0.0 4.6 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_11 PF13414.6 OQS05501.1 - 8.9e-19 66.9 2.5 7.8e-06 25.5 0.0 4.4 1 1 3 4 4 4 4 TPR repeat TPR_2 PF07719.17 OQS05501.1 - 3.3e-18 64.3 1.0 0.00078 19.4 0.0 4.6 4 0 0 4 4 4 4 Tetratricopeptide repeat cNMP_binding PF00027.29 OQS05501.1 - 1.7e-12 47.2 0.1 0.016 15.3 0.0 4.2 4 0 0 4 4 4 3 Cyclic nucleotide-binding domain TPR_17 PF13431.6 OQS05501.1 - 3.2e-11 42.8 1.3 0.0038 17.5 0.0 3.8 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.6 OQS05501.1 - 1.7e-10 40.2 3.3 0.0013 18.8 0.1 4.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 OQS05501.1 - 4.1e-10 39.8 0.0 3.4e-05 24.1 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 OQS05501.1 - 2.9e-09 37.4 0.0 4.4e-05 24.0 0.0 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.6 OQS05501.1 - 1.9e-08 33.8 0.5 0.0029 17.5 0.0 4.7 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.6 OQS05501.1 - 5.3e-08 33.3 0.0 0.001 19.6 0.0 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 OQS05501.1 - 3.5e-06 27.4 0.0 0.073 13.9 0.0 4.1 1 1 3 4 4 4 2 Tetratricopeptide repeat TPR_9 PF13371.6 OQS05501.1 - 6.6e-06 26.2 0.0 0.053 13.7 0.0 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.6 OQS05501.1 - 2.2e-05 24.8 2.8 0.095 13.4 0.0 4.6 4 0 0 4 4 4 1 Tetratricopeptide repeat ANAPC3 PF12895.7 OQS05501.1 - 0.0014 18.8 2.4 0.037 14.2 1.5 3.1 1 1 1 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 BTAD PF03704.17 OQS05501.1 - 0.0058 17.1 0.0 7.8 6.9 0.0 2.8 3 0 0 3 3 3 2 Bacterial transcriptional activator domain SHNi-TPR PF10516.9 OQS05501.1 - 0.01 15.3 0.1 0.24 10.9 0.0 3.0 2 0 0 2 2 2 0 SHNi-TPR TPR_10 PF13374.6 OQS05501.1 - 0.19 11.7 0.9 11 6.1 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat Aminotran_5 PF00266.19 OQS05502.1 - 5e-60 203.4 0.4 3.2e-59 200.8 0.4 1.9 1 1 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 OQS05502.1 - 6.2e-08 32.2 0.0 1.6e-07 30.9 0.0 1.6 2 0 0 2 2 2 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 OQS05502.1 - 3.1e-07 29.3 0.1 4.4e-07 28.8 0.1 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 OQS05502.1 - 1.9e-06 27.4 1.0 2.9e-06 26.9 1.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family SpoU_methylase PF00588.19 OQS05502.1 - 0.0082 16.3 0.2 0.017 15.3 0.2 1.5 1 0 0 1 1 1 1 SpoU rRNA Methylase family PheRS_DBD1 PF18552.1 OQS05502.1 - 0.042 13.6 0.1 0.56 10.0 0.0 2.3 2 0 0 2 2 2 0 PheRS DNA binding domain 1 DUF2855 PF11017.8 OQS05502.1 - 0.12 12.1 0.0 0.18 11.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2855) DinB PF05163.12 OQS05503.1 - 3.6e-20 72.5 0.0 7.1e-20 71.6 0.0 1.4 1 0 0 1 1 1 1 DinB family DUF4743 PF15916.5 OQS05503.1 - 1.4e-12 47.6 0.0 3e-12 46.6 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4743) DinB_2 PF12867.7 OQS05503.1 - 1.7e-10 41.5 0.1 3.2e-10 40.6 0.1 1.4 1 0 0 1 1 1 1 DinB superfamily NUDIX PF00293.28 OQS05503.1 - 1e-07 32.0 0.0 2.8e-07 30.6 0.0 1.6 2 0 0 2 2 2 1 NUDIX domain VirC1 PF07015.11 OQS05503.1 - 0.014 14.7 0.0 0.033 13.5 0.0 1.6 1 0 0 1 1 1 0 VirC1 protein Pkinase PF00069.25 OQS05504.1 - 2.2e-75 253.4 0.0 3.5e-75 252.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQS05504.1 - 5.2e-33 114.4 0.0 8.9e-33 113.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase EF-hand_1 PF00036.32 OQS05504.1 - 2.7e-25 86.0 7.5 2.7e-08 32.8 0.1 4.7 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 OQS05504.1 - 1.1e-23 83.4 1.8 8e-11 42.2 0.4 2.8 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 OQS05504.1 - 6e-21 72.5 4.4 7.6e-05 22.3 0.0 4.7 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 OQS05504.1 - 1.2e-19 69.8 5.9 4.7e-11 42.4 0.6 3.3 1 1 2 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.6 OQS05504.1 - 4.2e-19 67.1 5.3 1.1e-05 24.7 0.1 4.5 4 0 0 4 4 4 4 EF hand Kdo PF06293.14 OQS05504.1 - 4.6e-07 29.4 0.3 9e-07 28.4 0.3 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family EF-hand_9 PF14658.6 OQS05504.1 - 6.2e-06 26.4 0.2 0.16 12.3 0.0 2.8 2 1 0 2 2 2 2 EF-hand domain APH PF01636.23 OQS05504.1 - 1.1e-05 25.5 0.1 8.2e-05 22.6 0.0 1.9 1 1 1 2 2 2 1 Phosphotransferase enzyme family EF-hand_4 PF12763.7 OQS05504.1 - 3.5e-05 23.7 1.1 0.03 14.3 0.1 2.8 1 1 1 3 3 3 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 OQS05504.1 - 0.0002 21.6 0.0 0.54 10.6 0.0 2.5 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region Choline_kinase PF01633.20 OQS05504.1 - 0.0017 18.0 0.0 0.0037 16.9 0.0 1.5 1 0 0 1 1 1 1 Choline/ethanolamine kinase Caleosin PF05042.13 OQS05504.1 - 0.0047 16.9 0.1 0.3 11.0 0.0 2.8 2 1 1 3 3 3 1 Caleosin related protein EcKinase PF02958.20 OQS05504.1 - 0.046 13.0 0.0 0.079 12.3 0.0 1.3 1 0 0 1 1 1 0 Ecdysteroid kinase His_Phos_1 PF00300.22 OQS05506.1 - 5e-18 65.5 0.0 6.5e-17 61.9 0.0 2.4 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Flavi_DEAD PF07652.14 OQS05506.1 - 0.07 13.1 0.1 0.16 11.9 0.0 1.5 2 0 0 2 2 2 0 Flavivirus DEAD domain Pkinase PF00069.25 OQS05507.1 - 4.7e-51 173.7 0.0 6.7e-51 173.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQS05507.1 - 6.5e-48 163.3 0.0 1e-47 162.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase WD40 PF00400.32 OQS05507.1 - 1.8e-29 101.4 12.2 1.7e-05 25.5 0.0 9.4 10 0 0 10 10 10 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OQS05507.1 - 3.1e-05 24.2 0.0 0.18 12.1 0.0 3.8 4 0 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Pkinase_fungal PF17667.1 OQS05507.1 - 0.00056 18.8 0.1 0.00089 18.1 0.1 1.2 1 0 0 1 1 1 1 Fungal protein kinase Vps16_N PF04841.13 OQS05507.1 - 0.19 10.4 0.0 0.34 9.6 0.0 1.3 1 0 0 1 1 1 0 Vps16, N-terminal region Ku PF02735.16 OQS05508.1 - 5.4e-52 176.5 0.0 8.4e-52 175.8 0.0 1.3 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_N PF03731.15 OQS05508.1 - 9.1e-25 87.7 0.4 1.6e-24 86.9 0.4 1.4 1 0 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain Ku_C PF03730.14 OQS05508.1 - 3.9e-12 46.7 0.1 1.2e-11 45.2 0.1 1.8 1 0 0 1 1 1 1 Ku70/Ku80 C-terminal arm SAP PF02037.27 OQS05508.1 - 7.7e-07 28.7 0.0 2.3e-06 27.2 0.0 1.8 1 0 0 1 1 1 1 SAP domain Ish1 PF10281.9 OQS05508.1 - 0.021 15.1 0.0 0.063 13.6 0.0 1.9 1 0 0 1 1 1 0 Putative stress-responsive nuclear envelope protein PepX_N PF09168.10 OQS05508.1 - 0.078 13.4 1.7 1.1 9.7 0.1 3.1 3 0 0 3 3 3 0 X-Prolyl dipeptidyl aminopeptidase PepX, N-terminal Phage_TAC_5 PF08890.11 OQS05508.1 - 0.11 12.5 0.1 0.47 10.5 0.0 2.0 2 0 0 2 2 2 0 Phage XkdN-like tail assembly chaperone protein, TAC p450 PF00067.22 OQS05509.1 - 1.4e-94 317.4 0.0 1.8e-94 317.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DnaJ PF00226.31 OQS05509.1 - 2.1e-21 75.8 0.5 4.2e-21 74.8 0.5 1.5 1 0 0 1 1 1 1 DnaJ domain fn3 PF00041.21 OQS05510.1 - 2.8e-10 40.4 0.2 5.7e-10 39.4 0.2 1.5 1 0 0 1 1 1 1 Fibronectin type III domain TSP_1 PF00090.19 OQS05510.1 - 0.0004 20.5 4.7 0.0004 20.5 4.7 2.1 2 0 0 2 2 2 1 Thrombospondin type 1 domain EGF_2 PF07974.13 OQS05510.1 - 0.025 14.9 0.5 0.025 14.9 0.5 2.0 2 1 0 2 2 2 0 EGF-like domain fn3_4 PF16794.5 OQS05510.1 - 0.082 12.8 0.0 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 Fibronectin-III type domain DUF5593 PF18007.1 OQS05510.1 - 0.13 13.0 0.3 28 5.5 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF5593) EGF PF00008.27 OQS05510.1 - 0.39 11.1 6.6 1.4 9.3 6.6 2.0 1 0 0 1 1 1 0 EGF-like domain EGF_alliinase PF04863.13 OQS05510.1 - 0.46 10.9 4.1 1.1 9.7 4.1 1.6 1 0 0 1 1 1 0 Alliinase EGF-like domain TPR_2 PF07719.17 OQS05511.1 - 3.8e-14 51.6 2.6 0.0015 18.5 0.0 5.6 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_1 PF00515.28 OQS05511.1 - 5.2e-14 51.4 2.0 0.00044 19.9 0.1 5.6 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_19 PF14559.6 OQS05511.1 - 1.2e-12 48.2 3.3 2.7e-07 31.0 0.0 4.4 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_9 PF13371.6 OQS05511.1 - 4.3e-08 33.2 0.3 0.0066 16.6 0.0 3.0 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.6 OQS05511.1 - 9.6e-08 32.5 0.1 0.025 15.2 0.0 4.3 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 OQS05511.1 - 1.4e-06 28.5 4.5 0.052 13.8 0.1 4.5 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_14 PF13428.6 OQS05511.1 - 3.1e-06 27.5 2.0 0.46 11.4 0.0 4.9 4 1 1 5 5 4 2 Tetratricopeptide repeat TPR_11 PF13414.6 OQS05511.1 - 3.7e-06 26.5 0.0 0.00014 21.4 0.0 2.7 2 0 0 2 2 2 1 TPR repeat TPR_8 PF13181.6 OQS05511.1 - 9e-06 25.5 0.2 1.3 9.4 0.0 5.2 4 0 0 4 4 4 1 Tetratricopeptide repeat ANAPC3 PF12895.7 OQS05511.1 - 1e-05 25.6 6.5 0.0069 16.6 0.1 4.0 4 1 0 4 4 4 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_20 PF14561.6 OQS05511.1 - 0.00016 21.9 1.4 0.47 10.8 0.0 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.6 OQS05511.1 - 0.00026 21.1 0.1 0.0061 16.9 0.0 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 OQS05511.1 - 0.0054 16.7 1.3 21 5.4 0.0 4.5 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.6 OQS05511.1 - 0.12 13.1 9.1 43 5.0 0.0 5.4 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_3 PF07720.12 OQS05511.1 - 0.14 12.2 0.4 1.5 8.9 0.1 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat Peptidase_S28 PF05577.12 OQS05512.1 - 6.6e-61 206.4 1.4 1.3e-60 205.4 1.4 1.4 1 0 0 1 1 1 1 Serine carboxypeptidase S28 DEAD PF00270.29 OQS05512.1 - 1.6e-37 128.9 0.0 5.2e-37 127.3 0.0 1.9 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OQS05512.1 - 1.2e-26 93.2 0.0 5.2e-25 88.0 0.0 2.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 OQS05512.1 - 8.1e-08 32.5 1.3 2.2e-07 31.0 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Hydrolase_4 PF12146.8 OQS05512.1 - 8e-05 22.0 0.0 0.00023 20.5 0.0 1.7 1 0 0 1 1 1 1 Serine aminopeptidase, S33 UTP25 PF06862.12 OQS05512.1 - 0.018 13.9 0.2 2.3 6.9 0.0 2.9 4 0 0 4 4 4 0 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 Peptidase_S37 PF05576.11 OQS05512.1 - 0.13 10.9 0.0 0.22 10.2 0.0 1.2 1 0 0 1 1 1 0 PS-10 peptidase S37 Na_trans_assoc PF06512.13 OQS05512.1 - 6.5 7.0 13.7 0.24 11.6 5.9 2.4 3 0 0 3 3 3 0 Sodium ion transport-associated DMP1 PF07263.11 OQS05512.1 - 7.3 5.4 20.8 0.17 10.7 13.0 1.8 2 0 0 2 2 2 0 Dentin matrix protein 1 (DMP1) SMI1_KNR4 PF09346.10 OQS05513.1 - 4.4e-06 27.1 0.0 6.2e-05 23.4 0.0 2.1 1 1 0 1 1 1 1 SMI1 / KNR4 family (SUKH-1) SUKH_6 PF14568.6 OQS05513.1 - 0.00028 21.3 0.0 0.0088 16.5 0.0 2.2 1 1 0 1 1 1 1 SMI1-KNR4 cell-wall SUKH_5 PF14567.6 OQS05513.1 - 0.074 12.8 0.0 0.49 10.1 0.0 2.0 1 1 0 1 1 1 0 SMI1-KNR4 cell-wall Peptidase_C26 PF07722.13 OQS05514.1 - 1e-21 77.7 0.0 1.9e-20 73.6 0.0 2.2 1 1 0 1 1 1 1 Peptidase C26 GATase PF00117.28 OQS05514.1 - 2.1e-11 44.0 0.0 3.6e-11 43.2 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I DUF2514 PF10721.9 OQS05515.1 - 0.016 15.2 1.3 0.62 10.1 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2514) TRAP_beta PF05753.14 OQS05515.1 - 0.089 12.2 0.1 0.23 10.8 0.1 1.6 2 0 0 2 2 2 0 Translocon-associated protein beta (TRAPB) Pkinase PF00069.25 OQS05517.1 - 4.2e-69 232.9 0.0 7e-69 232.1 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain cNMP_binding PF00027.29 OQS05517.1 - 1.7e-59 197.8 0.6 7.7e-21 74.0 0.0 4.0 4 0 0 4 4 4 3 Cyclic nucleotide-binding domain Pkinase_Tyr PF07714.17 OQS05517.1 - 2.3e-34 118.8 0.0 4e-34 118.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OQS05517.1 - 0.0024 17.2 0.0 0.0042 16.4 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 OQS05517.1 - 0.0038 17.2 0.0 0.016 15.2 0.0 1.9 2 1 1 3 3 3 1 Phosphotransferase enzyme family 7TMR-HDED PF07697.11 OQS05517.1 - 0.065 13.3 0.6 1.5 8.9 0.0 2.8 4 0 0 4 4 4 0 7TM-HD extracellular Seadorna_VP7 PF07387.11 OQS05517.1 - 0.078 12.0 0.0 0.14 11.2 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 DS PF01916.17 OQS05518.1 - 3.1e-135 450.0 0.0 4.2e-135 449.6 0.0 1.2 1 0 0 1 1 1 1 Deoxyhypusine synthase Fcf1 PF04900.12 OQS05519.1 - 4.4e-16 59.1 0.0 8.4e-16 58.2 0.0 1.5 1 0 0 1 1 1 1 Fcf1 PIN_9 PF18477.1 OQS05519.1 - 1.2e-09 38.4 0.3 2.1e-09 37.7 0.3 1.4 1 0 0 1 1 1 1 PIN like domain Rad21_Rec8_N PF04825.13 OQS05519.1 - 0.0065 16.6 0.3 0.013 15.6 0.3 1.5 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein SET PF00856.28 OQS05520.1 - 6.5e-18 65.7 4.6 3.6e-17 63.2 0.3 3.5 3 1 0 3 3 3 1 SET domain PHD PF00628.29 OQS05520.1 - 8.3e-13 48.0 34.5 1.2e-08 34.7 3.4 3.9 3 1 1 4 4 4 3 PHD-finger AWS PF17907.1 OQS05520.1 - 0.0015 18.5 4.5 0.0022 18.0 0.3 3.1 2 0 0 2 2 2 1 AWS domain zf-HC5HC2H PF13771.6 OQS05520.1 - 0.061 13.6 28.4 0.12 12.7 10.7 3.9 1 1 2 3 3 3 0 PHD-like zinc-binding domain DTW PF03942.15 OQS05521.1 - 3.4e-17 62.8 0.1 1.4e-16 60.8 0.0 1.9 2 0 0 2 2 2 1 DTW domain zf-CCHC PF00098.23 OQS05521.1 - 1.7e-06 27.8 4.0 1.7e-06 27.8 4.0 2.9 1 1 1 2 2 2 1 Zinc knuckle zf-CCHC_4 PF14392.6 OQS05521.1 - 0.056 13.2 0.2 0.056 13.2 0.2 2.3 2 0 0 2 2 2 0 Zinc knuckle Pkinase PF00069.25 OQS05522.1 - 5e-34 117.9 0.0 6e-34 117.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQS05522.1 - 1.4e-30 106.5 0.1 1.6e-30 106.3 0.1 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Choline_kinase PF01633.20 OQS05522.1 - 0.066 12.8 0.5 0.096 12.3 0.5 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase Kinase-like PF14531.6 OQS05522.1 - 0.082 12.2 0.0 0.11 11.9 0.0 1.1 1 0 0 1 1 1 0 Kinase-like Tetraspanin PF00335.20 OQS05523.1 - 3.4e-17 62.9 17.6 1e-16 61.4 17.6 1.7 1 1 0 1 1 1 1 Tetraspanin family FA_desaturase PF00487.24 OQS05523.1 - 0.018 14.9 2.3 0.018 14.9 2.3 1.7 2 0 0 2 2 2 0 Fatty acid desaturase Baculo_11_kDa PF06143.11 OQS05523.1 - 0.04 13.5 0.4 0.04 13.5 0.4 2.4 3 0 0 3 3 3 0 Baculovirus 11 kDa family DUF2615 PF11027.8 OQS05523.1 - 0.041 14.0 4.8 3.1 8.0 0.1 3.5 4 0 0 4 4 4 0 Protein of unknown function (DUF2615) DUF2981 PF11200.8 OQS05523.1 - 0.13 12.0 7.2 0.097 12.4 5.6 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2981) Phage_holin_3_6 PF07332.11 OQS05523.1 - 0.93 9.6 16.0 0.26 11.3 4.3 3.1 3 0 0 3 3 3 0 Putative Actinobacterial Holin-X, holin superfamily III Pkinase PF00069.25 OQS05525.1 - 1.8e-66 224.2 0.0 2.1e-66 224.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQS05525.1 - 5.1e-22 78.4 0.0 7.6e-22 77.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 OQS05525.1 - 3.2e-07 30.5 0.0 3.8e-05 23.7 0.2 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 OQS05525.1 - 0.00062 18.7 0.1 0.0023 16.8 0.0 1.8 2 0 0 2 2 2 1 Fungal protein kinase Kdo PF06293.14 OQS05525.1 - 0.0048 16.3 0.1 0.008 15.5 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 OQS05525.1 - 0.026 14.1 0.2 0.046 13.3 0.2 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase DUF2459 PF09601.10 OQS05525.1 - 0.097 12.5 0.0 0.23 11.2 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2459) Pyr_redox_2 PF07992.14 OQS05526.1 - 7e-75 252.0 1.4 1.8e-37 129.1 1.7 2.0 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 OQS05526.1 - 5.3e-31 107.0 4.2 9.2e-09 35.7 0.1 5.2 5 0 0 5 5 4 4 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 OQS05526.1 - 2.5e-15 56.5 3.2 2.2e-06 27.2 0.2 4.1 3 1 0 4 4 4 3 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 OQS05526.1 - 1.3e-13 51.3 10.3 0.011 15.4 0.2 6.9 5 2 1 7 7 7 3 FAD dependent oxidoreductase K_oxygenase PF13434.6 OQS05526.1 - 6.7e-13 48.5 3.2 0.00056 19.2 0.2 4.5 3 1 2 5 5 5 3 L-lysine 6-monooxygenase (NADPH-requiring) Lycopene_cycl PF05834.12 OQS05526.1 - 8e-13 48.2 1.5 0.027 13.5 0.1 4.7 4 1 1 5 5 5 4 Lycopene cyclase protein NAD_binding_9 PF13454.6 OQS05526.1 - 9.2e-09 35.5 2.5 0.73 9.8 0.2 6.3 4 2 2 6 6 6 2 FAD-NAD(P)-binding TrkA_N PF02254.18 OQS05526.1 - 6.6e-08 32.8 6.3 0.048 13.9 0.1 5.2 5 0 0 5 5 4 2 TrkA-N domain ThiF PF00899.21 OQS05526.1 - 1.2e-07 31.3 0.9 0.11 11.8 0.0 4.9 4 1 0 4 4 4 2 ThiF family Trp_halogenase PF04820.14 OQS05526.1 - 1.3e-07 30.9 7.8 0.00075 18.5 0.4 4.1 4 0 0 4 4 4 2 Tryptophan halogenase NAD_binding_7 PF13241.6 OQS05526.1 - 2.8e-07 30.9 1.4 0.68 10.4 0.1 4.4 4 0 0 4 4 4 2 Putative NAD(P)-binding NAD_binding_8 PF13450.6 OQS05526.1 - 3.2e-07 30.5 3.8 0.49 10.7 0.2 4.7 4 0 0 4 4 4 2 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 OQS05526.1 - 2.6e-06 26.9 7.6 0.31 10.2 0.2 4.4 4 0 0 4 4 4 3 Thi4 family AlaDh_PNT_C PF01262.21 OQS05526.1 - 3.2e-06 26.6 5.8 0.039 13.2 0.1 4.2 4 0 0 4 4 4 2 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.14 OQS05526.1 - 3.8e-05 22.6 7.4 1.3 7.7 0.3 5.5 7 0 0 7 7 7 2 HI0933-like protein GIDA PF01134.22 OQS05526.1 - 0.00053 19.2 13.3 6.7 5.7 0.1 5.6 5 1 1 6 6 6 0 Glucose inhibited division protein A NAD_Gly3P_dh_N PF01210.23 OQS05526.1 - 0.00059 19.8 1.1 5.8 6.9 0.1 4.2 3 1 1 4 4 4 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus FAD_binding_3 PF01494.19 OQS05526.1 - 0.00074 18.9 4.5 5.4 6.1 0.3 4.8 5 1 0 5 5 5 1 FAD binding domain 3HCDH_N PF02737.18 OQS05526.1 - 0.0008 19.3 6.7 2.3 8.1 0.0 4.3 4 0 0 4 4 4 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ApbA PF02558.16 OQS05526.1 - 0.0016 18.1 0.3 1.1 8.9 0.1 3.3 3 0 0 3 3 2 1 Ketopantoate reductase PanE/ApbA Sacchrp_dh_NADP PF03435.18 OQS05526.1 - 0.02 15.1 9.6 0.34 11.1 0.2 4.2 4 0 0 4 4 4 0 Saccharopine dehydrogenase NADP binding domain FAD_binding_2 PF00890.24 OQS05526.1 - 0.074 12.1 4.9 3.3 6.7 0.0 3.5 3 1 0 3 3 3 0 FAD binding domain Shikimate_DH PF01488.20 OQS05526.1 - 0.084 12.9 5.0 29 4.7 0.2 4.9 6 0 0 6 6 5 0 Shikimate / quinate 5-dehydrogenase GFO_IDH_MocA PF01408.22 OQS05526.1 - 0.43 11.4 2.4 66 4.4 0.0 4.2 5 0 0 5 5 4 0 Oxidoreductase family, NAD-binding Rossmann fold UDPG_MGDP_dh_N PF03721.14 OQS05526.1 - 0.64 9.6 12.8 5.3 6.6 0.1 4.6 4 1 0 4 4 4 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Malic_M PF03949.15 OQS05526.1 - 2.7 7.2 8.3 11 5.2 0.3 3.7 4 0 0 4 4 4 0 Malic enzyme, NAD binding domain SBBP PF06739.11 OQS05526.1 - 5.4 7.1 5.3 13 5.9 0.4 2.7 2 0 0 2 2 2 0 Beta-propeller repeat Acetyltransf_10 PF13673.7 OQS05527.1 - 6.6e-15 55.2 0.0 9.1e-15 54.7 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 OQS05527.1 - 5.8e-07 29.8 0.0 7.4e-07 29.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_5 PF13444.6 OQS05527.1 - 0.00029 21.5 0.1 0.00067 20.3 0.0 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 OQS05527.1 - 0.00038 20.7 0.0 0.00046 20.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.7 OQS05527.1 - 0.0012 18.9 0.0 0.0014 18.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 OQS05527.1 - 0.017 15.1 0.0 0.039 13.9 0.0 1.7 1 1 0 1 1 1 0 FR47-like protein Acetyltransf_13 PF13880.6 OQS05527.1 - 0.084 12.9 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 ESCO1/2 acetyl-transferase Peptidase_M54 PF07998.11 OQS05528.1 - 9.1e-11 42.1 0.1 2.9e-10 40.4 0.1 1.9 1 1 1 2 2 2 1 Peptidase family M54 Zincin_1 PF06262.11 OQS05528.1 - 0.025 14.6 0.0 0.056 13.6 0.0 1.5 1 0 0 1 1 1 0 Zincin-like metallopeptidase Reprolysin_4 PF13583.6 OQS05528.1 - 0.035 13.8 0.0 0.066 12.9 0.0 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.6 OQS05528.1 - 0.068 13.3 0.1 0.13 12.4 0.1 1.5 1 0 0 1 1 1 0 Metallo-peptidase family M12 Metallopep PF12044.8 OQS05528.1 - 0.1 11.2 0.2 0.15 10.6 0.2 1.2 1 0 0 1 1 1 0 Putative peptidase family Reprolysin_3 PF13582.6 OQS05528.1 - 0.12 12.9 0.8 0.19 12.3 0.2 1.8 2 1 0 2 2 2 0 Metallo-peptidase family M12B Reprolysin-like Aa_trans PF01490.18 OQS05530.1 - 3.3e-15 55.7 25.7 5.3e-08 32.0 2.0 2.2 2 0 0 2 2 2 2 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 OQS05530.1 - 6.1e-06 25.5 24.3 0.00053 19.1 0.9 2.9 2 1 0 2 2 2 2 Tryptophan/tyrosine permease family IQ PF00612.27 OQS05530.1 - 8.4e-05 22.0 26.2 0.0059 16.3 1.0 5.2 4 0 0 4 4 4 3 IQ calmodulin-binding motif DUF3302 PF11742.8 OQS05530.1 - 0.11 12.7 1.4 19 5.5 0.0 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3302) Kri1 PF05178.12 OQS05530.1 - 1.3 9.6 8.4 1.4 9.5 3.2 2.4 2 0 0 2 2 2 0 KRI1-like family Ank_2 PF12796.7 OQS05531.1 - 1.2e-38 131.6 3.3 2.1e-12 47.5 0.1 4.5 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQS05531.1 - 2.8e-29 101.1 5.6 6.3e-07 29.8 0.0 6.4 2 2 4 6 6 6 6 Ankyrin repeats (many copies) Ank PF00023.30 OQS05531.1 - 2.7e-27 94.0 11.7 4.4e-07 30.1 0.1 7.9 7 2 0 7 7 7 5 Ankyrin repeat Ank_3 PF13606.6 OQS05531.1 - 9.3e-26 87.1 4.9 0.0004 20.6 0.0 7.7 8 2 1 9 9 9 5 Ankyrin repeat Ank_5 PF13857.6 OQS05531.1 - 4e-22 78.0 7.2 1.5e-06 28.4 0.2 5.8 3 2 1 5 5 5 5 Ankyrin repeats (many copies) Acetyltransf_10 PF13673.7 OQS05532.1 - 4.8e-18 65.3 0.0 5.6e-18 65.1 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 OQS05532.1 - 1.4e-06 28.7 0.0 1.8e-06 28.3 0.0 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 OQS05532.1 - 1.1e-05 25.7 0.0 1.3e-05 25.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.7 OQS05532.1 - 0.00064 19.8 0.0 0.00071 19.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_5 PF13444.6 OQS05532.1 - 0.0016 19.2 0.0 0.0031 18.2 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 OQS05532.1 - 0.018 15.0 0.0 0.044 13.7 0.0 1.7 2 0 0 2 2 2 0 FR47-like protein Beta-Casp PF10996.8 OQS05533.1 - 0.048 14.0 0.1 17 5.7 0.0 2.8 2 0 0 2 2 2 0 Beta-Casp domain BAH PF01426.18 OQS05534.1 - 0.015 15.1 0.0 0.023 14.6 0.0 1.2 1 0 0 1 1 1 0 BAH domain Ank_2 PF12796.7 OQS05535.1 - 1e-41 141.4 1.6 1.6e-15 57.4 0.0 5.0 1 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.30 OQS05535.1 - 1.4e-39 132.8 7.2 8.9e-07 29.1 0.0 8.8 9 1 0 9 9 9 7 Ankyrin repeat Ank_4 PF13637.6 OQS05535.1 - 1.3e-35 121.3 0.8 1.8e-10 41.1 0.0 6.5 5 2 1 6 6 6 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQS05535.1 - 1.2e-29 99.1 4.1 6.9e-08 32.2 0.0 8.9 7 2 0 7 7 7 6 Ankyrin repeat Ank_5 PF13857.6 OQS05535.1 - 3.9e-28 97.1 2.0 6.3e-10 39.1 0.0 6.1 3 1 3 6 6 6 4 Ankyrin repeats (many copies) DUF452 PF04301.13 OQS05535.1 - 0.11 12.0 0.0 0.22 11.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF452) Ank_2 PF12796.7 OQS05538.1 - 2.1e-11 44.3 0.0 2.3e-11 44.1 0.0 1.1 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 OQS05538.1 - 3.3e-11 43.1 0.8 0.00089 19.6 0.0 3.0 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.6 OQS05538.1 - 1.2e-09 38.4 0.2 2e-05 25.1 0.0 2.1 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 OQS05538.1 - 4.1e-08 33.3 0.0 0.00028 21.1 0.0 2.0 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQS05538.1 - 4.3e-06 26.7 0.1 0.22 12.2 0.0 2.6 3 0 0 3 3 3 2 Ankyrin repeat Tubulin-binding PF00418.19 OQS05538.1 - 0.027 14.5 2.1 0.085 12.9 0.3 2.2 2 1 1 3 3 3 0 Tau and MAP protein, tubulin-binding repeat PDEase_II PF02112.15 OQS05539.1 - 0.035 13.2 0.3 0.067 12.3 0.2 1.3 1 1 0 1 1 1 0 cAMP phosphodiesterases class-II P22_AR_N PF10547.9 OQS05540.1 - 4.1e-05 23.9 0.0 7.7 6.9 0.0 4.5 4 0 0 4 4 4 1 P22_AR N-terminal domain DUF3417 PF11897.8 OQS05540.1 - 0.00011 22.6 2.4 7.4 7.1 0.0 5.4 5 0 0 5 5 5 1 Protein of unknown function (DUF3417) rhaM PF05336.13 OQS05540.1 - 0.0014 18.7 4.2 12 6.0 0.0 5.6 6 0 0 6 6 6 2 L-rhamnose mutarotase KH_7 PF17214.3 OQS05540.1 - 0.023 14.6 0.8 21 5.1 0.0 4.7 6 0 0 6 6 4 0 KH domain Cas1_AcylT PF07779.12 OQS05540.1 - 0.048 12.6 0.0 35 3.1 0.0 3.1 3 0 0 3 3 3 0 10 TM Acyl Transferase domain found in Cas1p E2 PF08199.11 OQS05540.1 - 0.059 13.3 0.0 35 4.4 0.0 3.8 3 0 0 3 3 3 0 Bacteriophage E2-like protein TrbM PF07424.11 OQS05540.1 - 0.1 12.5 2.0 37 4.2 0.1 4.4 5 1 0 5 5 5 0 TrbM Pathogen_betaC1 PF09593.10 OQS05540.1 - 0.12 12.3 0.4 18 5.3 0.1 2.6 2 0 0 2 2 2 0 Beta-satellite pathogenicity beta C1 protein Dak2 PF02734.17 OQS05540.1 - 0.19 11.6 0.4 0.8 9.6 0.2 2.0 2 0 0 2 2 2 0 DAK2 domain TIR PF01582.20 OQS05540.1 - 0.47 10.2 2.9 27 4.5 0.0 4.3 3 1 1 4 4 4 0 TIR domain kleA_kleC PF17383.2 OQS05540.1 - 2.2 8.7 8.4 84 3.6 0.1 4.8 4 0 0 4 4 4 0 Uncharacterized KorC regulated protein A THOC7 PF05615.13 OQS05540.1 - 2.6 8.3 22.2 4.7 7.5 0.5 4.8 4 0 0 4 4 4 0 Tho complex subunit 7 DicB PF05358.11 OQS05540.1 - 9.4 6.5 7.8 49 4.2 0.2 3.5 3 0 0 3 3 3 0 DicB protein Pyr_redox_2 PF07992.14 OQS05541.1 - 3.4e-34 118.4 0.6 4.5e-34 118.0 0.6 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Nitroreductase PF00881.24 OQS05541.1 - 4.3e-22 79.0 0.0 8e-22 78.1 0.0 1.5 1 0 0 1 1 1 1 Nitroreductase family Pyr_redox PF00070.27 OQS05541.1 - 4.7e-13 49.5 0.9 1.2e-07 32.2 0.1 2.7 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 OQS05541.1 - 9.9e-09 34.9 0.3 7.7e-07 28.7 0.1 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 OQS05541.1 - 1.1e-07 31.8 4.9 0.00029 20.5 0.0 3.5 2 2 2 4 4 4 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 OQS05541.1 - 9.7e-07 28.2 0.2 0.029 13.4 0.0 2.3 2 0 0 2 2 2 2 Lycopene cyclase protein K_oxygenase PF13434.6 OQS05541.1 - 2.1e-05 23.8 0.1 0.0022 17.2 0.0 2.4 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) TrkA_N PF02254.18 OQS05541.1 - 8e-05 22.9 0.5 0.091 13.0 0.0 3.6 3 0 0 3 3 3 1 TrkA-N domain Trp_halogenase PF04820.14 OQS05541.1 - 0.00013 20.9 0.1 0.0017 17.3 0.0 2.3 2 0 0 2 2 2 1 Tryptophan halogenase NAD_binding_9 PF13454.6 OQS05541.1 - 0.00035 20.6 0.1 0.018 15.1 0.0 2.9 3 0 0 3 3 3 1 FAD-NAD(P)-binding NAD_binding_7 PF13241.6 OQS05541.1 - 0.00036 20.9 0.2 1.7 9.2 0.1 3.0 3 0 0 3 3 3 2 Putative NAD(P)-binding NAD_binding_8 PF13450.6 OQS05541.1 - 0.0008 19.6 0.7 0.049 13.9 0.0 2.8 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain ThiF PF00899.21 OQS05541.1 - 0.0029 17.0 0.7 0.021 14.2 0.0 2.5 3 0 0 3 3 3 1 ThiF family HI0933_like PF03486.14 OQS05541.1 - 0.017 13.9 0.7 3.2 6.4 0.0 2.8 3 0 0 3 3 3 0 HI0933-like protein Thi4 PF01946.17 OQS05541.1 - 0.023 13.9 0.3 2.1 7.5 0.0 2.5 2 0 0 2 2 2 0 Thi4 family UDPG_MGDP_dh_N PF03721.14 OQS05541.1 - 0.028 14.0 0.4 2.7 7.5 0.1 2.4 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain TM1586_NiRdase PF14512.6 OQS05541.1 - 0.032 13.8 0.0 0.24 10.9 0.0 2.0 2 0 0 2 2 2 0 Putative TM nitroreductase Sacchrp_dh_NADP PF03435.18 OQS05541.1 - 0.094 13.0 1.1 0.36 11.1 0.2 2.3 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain ApbA PF02558.16 OQS05541.1 - 0.12 12.1 1.6 0.32 10.6 0.2 2.4 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA FAD_binding_3 PF01494.19 OQS05541.1 - 0.14 11.3 1.9 1 8.6 0.0 2.7 2 1 1 3 3 3 0 FAD binding domain GIDA PF01134.22 OQS05541.1 - 0.36 9.9 6.3 2 7.4 0.5 2.9 3 0 0 3 3 3 0 Glucose inhibited division protein A MFS_1 PF07690.16 OQS05542.1 - 7.5e-25 87.6 20.5 7.5e-25 87.6 20.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily ABC_membrane PF00664.23 OQS05543.1 - 4.6e-100 334.8 32.1 2e-51 175.2 8.6 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 OQS05543.1 - 9.8e-72 239.9 0.0 4.9e-36 124.3 0.0 2.4 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 OQS05543.1 - 4.1e-13 49.3 0.0 0.0002 20.9 0.0 3.6 1 1 2 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 OQS05543.1 - 4.9e-08 33.5 1.1 0.001 19.5 0.0 2.7 2 1 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.6 OQS05543.1 - 7.1e-07 28.9 0.5 0.0046 16.7 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain Zeta_toxin PF06414.12 OQS05543.1 - 3.3e-06 26.5 0.0 0.021 14.1 0.0 2.4 2 0 0 2 2 2 2 Zeta toxin AAA_25 PF13481.6 OQS05543.1 - 4.1e-06 26.5 0.7 0.09 12.3 0.0 3.6 3 0 0 3 3 3 2 AAA domain AAA_21 PF13304.6 OQS05543.1 - 1.9e-05 24.7 0.3 2 8.2 0.0 4.1 3 1 0 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_5 PF07728.14 OQS05543.1 - 2.4e-05 24.3 1.2 0.18 11.8 0.0 4.2 4 0 0 4 4 4 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 OQS05543.1 - 2.6e-05 24.5 3.2 0.1 12.8 0.1 3.8 2 2 0 2 2 2 2 AAA domain AAA PF00004.29 OQS05543.1 - 4e-05 24.1 7.2 0.033 14.6 0.2 4.3 2 2 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) ABC_ATPase PF09818.9 OQS05543.1 - 4.5e-05 22.4 1.4 0.14 10.9 0.0 2.7 3 0 0 3 3 3 2 Predicted ATPase of the ABC class RsgA_GTPase PF03193.16 OQS05543.1 - 5.8e-05 23.1 0.0 0.32 10.9 0.0 2.6 2 0 0 2 2 2 2 RsgA GTPase AAA_15 PF13175.6 OQS05543.1 - 0.00021 21.1 0.0 0.4 10.3 0.0 2.3 2 0 0 2 2 2 2 AAA ATPase domain AAA_7 PF12775.7 OQS05543.1 - 0.00028 20.5 0.1 0.27 10.7 0.0 3.0 3 0 0 3 3 2 1 P-loop containing dynein motor region AAA_30 PF13604.6 OQS05543.1 - 0.00033 20.4 0.7 0.66 9.7 0.0 3.2 2 2 0 2 2 2 2 AAA domain AAA_28 PF13521.6 OQS05543.1 - 0.00049 20.4 0.1 1 9.6 0.0 2.6 2 0 0 2 2 2 2 AAA domain G-alpha PF00503.20 OQS05543.1 - 0.00049 19.4 0.0 0.29 10.2 0.0 2.3 2 0 0 2 2 2 2 G-protein alpha subunit AAA_24 PF13479.6 OQS05543.1 - 0.0013 18.5 0.3 0.33 10.7 0.0 2.9 2 1 1 3 3 3 1 AAA domain SbcCD_C PF13558.6 OQS05543.1 - 0.0014 18.8 4.2 0.86 9.9 0.4 3.9 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_18 PF13238.6 OQS05543.1 - 0.0018 18.8 1.2 0.61 10.6 0.0 2.9 3 0 0 3 3 2 1 AAA domain AAA_33 PF13671.6 OQS05543.1 - 0.0029 17.8 0.0 0.95 9.6 0.0 2.7 2 0 0 2 2 2 1 AAA domain Rad17 PF03215.15 OQS05543.1 - 0.0045 16.9 0.1 7.5 6.4 0.0 3.1 3 0 0 3 3 3 0 Rad17 P-loop domain APS_kinase PF01583.20 OQS05543.1 - 0.0058 16.5 0.1 0.73 9.7 0.0 2.5 2 0 0 2 2 2 1 Adenylylsulphate kinase RNA_helicase PF00910.22 OQS05543.1 - 0.0094 16.3 0.0 6.2 7.3 0.0 2.7 2 0 0 2 2 2 0 RNA helicase MMR_HSR1 PF01926.23 OQS05543.1 - 0.014 15.4 0.1 7.5 6.7 0.0 2.7 2 0 0 2 2 2 0 50S ribosome-binding GTPase DUF87 PF01935.17 OQS05543.1 - 0.018 15.2 1.3 1.5 8.8 0.0 2.7 3 0 0 3 3 2 0 Helicase HerA, central domain DUF815 PF05673.13 OQS05543.1 - 0.018 14.2 0.0 5.6 6.0 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_23 PF13476.6 OQS05543.1 - 0.019 15.5 0.0 3.2 8.2 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.6 OQS05543.1 - 0.033 14.2 0.1 8.9 6.4 0.0 3.3 4 0 0 4 4 3 0 AAA domain NB-ARC PF00931.22 OQS05543.1 - 0.08 12.1 0.1 13 4.9 0.0 2.4 2 0 0 2 2 2 0 NB-ARC domain Mg_chelatase PF01078.21 OQS05543.1 - 0.11 11.8 0.0 5 6.5 0.0 2.8 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI ATP-synt_ab PF00006.25 OQS05543.1 - 0.14 11.8 0.0 8.8 5.9 0.0 2.5 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain Roc PF08477.13 OQS05543.1 - 0.15 12.3 0.0 4.6 7.5 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase DEAD PF00270.29 OQS05543.1 - 0.16 11.8 2.6 14 5.4 0.2 3.5 2 2 0 2 2 2 0 DEAD/DEAH box helicase NTPase_1 PF03266.15 OQS05543.1 - 0.19 11.6 2.3 16 5.4 0.0 3.5 4 0 0 4 4 3 0 NTPase AAA_17 PF13207.6 OQS05543.1 - 1.2 9.6 3.5 24 5.3 0.0 3.2 4 0 0 4 4 2 0 AAA domain Reticulon PF02453.17 OQS05543.1 - 1.2 9.1 4.7 0.59 10.1 0.7 2.5 2 0 0 2 2 2 0 Reticulon NACHT PF05729.12 OQS05543.1 - 2.7 7.9 5.8 24 4.8 0.1 3.3 4 0 0 4 4 3 0 NACHT domain PLAC8 PF04749.17 OQS05544.1 - 4.7e-14 53.2 3.7 6.3e-14 52.8 3.7 1.2 1 0 0 1 1 1 1 PLAC8 family Tcf25 PF04910.14 OQS05544.1 - 0.15 11.1 0.1 0.15 11.1 0.1 1.1 1 0 0 1 1 1 0 Transcriptional repressor TCF25 SusD-like_2 PF12771.7 OQS05544.1 - 0.21 10.5 0.0 0.28 10.1 0.0 1.1 1 0 0 1 1 1 0 Starch-binding associating with outer membrane DUF1129 PF06570.11 OQS05544.1 - 0.49 9.8 3.2 0.66 9.4 3.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) DUF4191 PF13829.6 OQS05544.1 - 0.95 8.8 2.3 1.4 8.3 2.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4191) Peptidase_C1 PF00112.23 OQS05545.1 - 4.3e-05 23.7 0.9 0.24 11.4 0.0 2.4 2 0 0 2 2 2 2 Papain family cysteine protease ALO PF04030.14 OQS05547.1 - 0.051 13.4 0.0 0.31 10.8 0.0 2.0 1 1 1 2 2 2 0 D-arabinono-1,4-lactone oxidase Mito_carr PF00153.27 OQS05548.1 - 3.9e-180 584.5 20.9 1.8e-25 88.7 0.0 9.6 6 2 3 9 9 9 9 Mitochondrial carrier protein Serine_protease PF18405.1 OQS05548.1 - 2e-09 37.0 2.7 0.074 12.2 0.0 6.9 7 0 0 7 7 7 3 Gammaproteobacterial serine protease DUF5518 PF17647.1 OQS05548.1 - 2.9e-05 24.2 14.1 0.4 10.8 0.2 6.7 7 1 0 7 7 7 3 Family of unknown function (DUF5518) SyrA PF11089.8 OQS05548.1 - 0.0021 18.1 0.4 3.6 7.7 0.0 2.9 2 0 0 2 2 2 2 Exopolysaccharide production repressor C_GCAxxG_C_C PF09719.10 OQS05548.1 - 0.066 13.5 0.2 13 6.1 0.0 2.8 2 0 0 2 2 2 0 Putative redox-active protein (C_GCAxxG_C_C) CRM1_repeat_3 PF18787.1 OQS05548.1 - 0.089 12.9 0.3 7.6 6.7 0.0 2.6 2 0 0 2 2 2 0 CRM1 / Exportin repeat 3 Pkinase_Tyr PF07714.17 OQS05549.1 - 7.7e-47 159.7 0.0 1.2e-46 159.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OQS05549.1 - 4.9e-46 157.2 0.0 9.7e-46 156.3 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 OQS05549.1 - 0.022 14.1 0.0 0.038 13.3 0.0 1.4 1 0 0 1 1 1 0 Kinase-like Kdo PF06293.14 OQS05549.1 - 0.038 13.3 0.0 0.11 11.8 0.0 1.8 2 1 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family stn_TNFRSF12A PF12191.8 OQS05549.1 - 0.18 12.0 0.0 0.37 11.0 0.0 1.4 1 0 0 1 1 1 0 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain DUF4381 PF14316.6 OQS05549.1 - 0.19 11.9 0.1 0.46 10.7 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) Sec1 PF00995.23 OQS05550.1 - 1.3e-100 338.4 0.0 1.5e-100 338.1 0.0 1.0 1 0 0 1 1 1 1 Sec1 family Sigma70_r4 PF04545.16 OQS05550.1 - 0.041 13.4 0.0 0.098 12.2 0.0 1.7 1 0 0 1 1 1 0 Sigma-70, region 4 Pkinase PF00069.25 OQS05551.1 - 9.6e-50 169.4 0.0 1.5e-49 168.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQS05551.1 - 2.7e-49 167.8 0.0 3.6e-49 167.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OQS05551.1 - 0.00029 19.8 0.0 0.00046 19.1 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 OQS05551.1 - 0.0004 19.8 0.0 0.00061 19.2 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family DUF4064 PF13273.6 OQS05551.1 - 0.0098 16.2 0.3 0.03 14.6 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF4064) LRR_4 PF12799.7 OQS05551.1 - 0.011 16.2 2.7 0.011 16.2 2.7 3.8 3 1 0 3 3 3 0 Leucine Rich repeats (2 copies) Orthoreo_P10 PF07204.11 OQS05551.1 - 0.054 13.4 0.0 0.13 12.3 0.0 1.5 1 0 0 1 1 1 0 Orthoreovirus membrane fusion protein p10 FTA2 PF13095.6 OQS05551.1 - 0.055 13.1 0.2 5.5 6.5 0.1 2.3 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Haspin_kinase PF12330.8 OQS05551.1 - 0.069 12.1 2.0 0.19 10.7 0.0 2.3 3 0 0 3 3 3 0 Haspin like kinase domain LRR_8 PF13855.6 OQS05551.1 - 0.38 10.5 8.7 0.68 9.7 2.9 2.9 2 1 1 3 3 3 0 Leucine rich repeat AMP-binding PF00501.28 OQS05552.1 - 3.2e-81 273.1 0.0 4e-81 272.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme DUF21 PF01595.20 OQS05553.1 - 2.7e-28 98.8 4.0 4.9e-28 98.0 4.0 1.3 1 0 0 1 1 1 1 Cyclin M transmembrane N-terminal domain DUF2666 PF10869.8 OQS05553.1 - 0.043 14.0 0.2 0.087 13.0 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2666) AA_permease PF00324.21 OQS05554.1 - 6.8e-36 123.9 45.7 1.2e-35 123.1 45.7 1.3 1 1 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 OQS05554.1 - 1.4e-34 119.7 48.0 1.9e-34 119.3 48.0 1.1 1 0 0 1 1 1 1 Amino acid permease Phage_holin_3_6 PF07332.11 OQS05554.1 - 0.056 13.5 0.2 0.056 13.5 0.2 5.3 3 2 1 4 4 4 0 Putative Actinobacterial Holin-X, holin superfamily III AA_permease_2 PF13520.6 OQS05555.1 - 2.3e-35 122.3 39.2 3.5e-35 121.7 39.1 1.3 1 1 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 OQS05555.1 - 2.9e-35 121.8 38.0 4.1e-35 121.3 38.0 1.2 1 0 0 1 1 1 1 Amino acid permease DNA_alkylation PF08713.11 OQS05556.1 - 5.8e-38 130.8 0.1 1.3e-37 129.6 0.1 1.6 1 1 0 1 1 1 1 DNA alkylation repair enzyme VASt PF16016.5 OQS05557.1 - 6.4e-30 104.6 0.0 9.7e-30 104.0 0.0 1.3 1 0 0 1 1 1 1 VAD1 Analog of StAR-related lipid transfer domain Rio2_N PF09202.11 OQS05557.1 - 0.029 14.6 0.2 0.073 13.3 0.1 1.7 2 0 0 2 2 2 0 Rio2, N-terminal YMF19 PF02326.15 OQS05557.1 - 0.063 14.1 0.3 0.18 12.6 0.1 1.8 2 0 0 2 2 2 0 Plant ATP synthase F0 ABC2_membrane PF01061.24 OQS05559.1 - 1.1e-32 113.2 29.1 1.1e-32 113.2 29.1 1.6 2 0 0 2 2 1 1 ABC-2 type transporter ABC_tran PF00005.27 OQS05559.1 - 4.2e-20 72.6 3.8 6.3e-12 46.2 0.0 2.4 2 0 0 2 2 2 2 ABC transporter AAA_29 PF13555.6 OQS05559.1 - 4.8e-06 26.2 1.9 0.011 15.5 0.5 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain Zeta_toxin PF06414.12 OQS05559.1 - 2.6e-05 23.6 1.7 0.0025 17.1 0.0 2.3 2 0 0 2 2 2 1 Zeta toxin RsgA_GTPase PF03193.16 OQS05559.1 - 3.3e-05 23.9 1.3 0.0079 16.1 0.4 2.3 2 0 0 2 2 2 1 RsgA GTPase AAA_16 PF13191.6 OQS05559.1 - 5.1e-05 23.7 0.3 0.032 14.6 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 OQS05559.1 - 0.0016 18.8 1.9 2.1 8.6 0.0 2.8 3 0 0 3 3 2 2 AAA domain AAA_25 PF13481.6 OQS05559.1 - 0.0024 17.5 0.8 0.47 10.0 0.2 2.4 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 OQS05559.1 - 0.0025 17.9 1.5 0.65 10.1 0.1 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase PDR_assoc PF08370.11 OQS05559.1 - 0.0034 17.1 0.1 0.0034 17.1 0.1 2.1 2 0 0 2 2 1 1 Plant PDR ABC transporter associated Roc PF08477.13 OQS05559.1 - 0.0063 16.7 1.1 0.63 10.3 0.0 2.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase AAA_21 PF13304.6 OQS05559.1 - 0.0084 16.0 1.3 2.6 7.8 0.2 2.4 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 OQS05559.1 - 0.014 14.8 1.9 19 4.6 0.1 4.0 3 1 0 3 3 3 0 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 OQS05559.1 - 0.014 15.9 1.6 0.64 10.5 1.0 2.3 2 0 0 2 2 2 0 AAA domain ABC_ATPase PF09818.9 OQS05559.1 - 0.021 13.6 0.0 0.51 9.1 0.0 2.1 2 0 0 2 2 2 0 Predicted ATPase of the ABC class Gtr1_RagA PF04670.12 OQS05559.1 - 0.047 13.0 0.5 5.7 6.2 0.0 2.4 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region FeoB_N PF02421.18 OQS05559.1 - 0.049 13.1 0.4 4.6 6.8 0.0 2.6 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_30 PF13604.6 OQS05559.1 - 0.059 13.1 1.0 3.3 7.4 1.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 OQS05559.1 - 0.061 13.9 0.3 7.8 7.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain PduV-EutP PF10662.9 OQS05559.1 - 0.066 13.0 2.7 3.1 7.5 0.4 3.2 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation AAA_33 PF13671.6 OQS05559.1 - 0.073 13.2 0.4 10 6.3 0.3 2.4 2 0 0 2 2 2 0 AAA domain Ploopntkinase3 PF18751.1 OQS05559.1 - 0.073 13.0 0.5 1.2 9.0 0.0 2.3 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 RNA_helicase PF00910.22 OQS05559.1 - 0.11 12.9 0.6 20 5.6 0.0 2.6 2 0 0 2 2 2 0 RNA helicase KTI12 PF08433.10 OQS05559.1 - 0.18 11.2 0.0 0.35 10.3 0.0 1.5 1 0 0 1 1 1 0 Chromatin associated protein KTI12 DUF87 PF01935.17 OQS05559.1 - 0.21 11.6 1.5 18 5.3 1.0 2.4 2 0 0 2 2 2 0 Helicase HerA, central domain AAA PF00004.29 OQS05559.1 - 0.25 11.8 0.7 40 4.6 0.0 2.5 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 OQS05559.1 - 0.55 10.1 2.4 5.6 6.9 0.8 2.5 2 0 0 2 2 2 0 NACHT domain cobW PF02492.19 OQS05559.1 - 1.2 8.7 2.8 1.8 8.2 0.7 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Pkinase_Tyr PF07714.17 OQS05560.1 - 3.8e-15 55.9 0.0 4.7e-15 55.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OQS05560.1 - 1.2e-09 37.9 0.0 1.4e-09 37.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain BET PF17035.5 OQS05561.1 - 3.8e-06 27.0 1.4 6.2e-06 26.3 0.0 2.0 3 0 0 3 3 3 1 Bromodomain extra-terminal - transcription regulation SF3b1 PF08920.10 OQS05562.1 - 2.6e-39 134.4 4.5 2.6e-39 134.4 4.5 4.8 1 1 3 4 4 4 1 Splicing factor 3B subunit 1 HEAT PF02985.22 OQS05562.1 - 3.7e-11 42.3 6.8 4.1 7.9 0.1 9.9 10 0 0 10 10 10 2 HEAT repeat HEAT_EZ PF13513.6 OQS05562.1 - 8.1e-10 39.0 2.9 0.28 11.7 0.0 7.4 7 1 1 8 8 8 2 HEAT-like repeat HEAT_2 PF13646.6 OQS05562.1 - 1.9e-07 31.4 5.1 0.056 13.8 0.0 7.0 6 2 2 8 8 8 3 HEAT repeats Cnd1 PF12717.7 OQS05562.1 - 3.8e-07 30.3 2.7 2.2 8.3 0.0 6.0 4 1 1 5 5 5 2 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 OQS05562.1 - 0.00014 20.6 0.7 0.045 12.3 0.0 3.1 2 1 1 3 3 3 2 Adaptin N terminal region Vac14_Fab1_bd PF12755.7 OQS05562.1 - 0.00024 21.6 0.1 0.64 10.7 0.0 4.4 4 0 0 4 4 4 1 Vacuolar 14 Fab1-binding region CLASP_N PF12348.8 OQS05562.1 - 0.01 15.4 0.3 0.84 9.2 0.0 2.5 2 0 0 2 2 2 0 CLASP N terminal UNC45-central PF11701.8 OQS05562.1 - 0.049 13.6 0.0 0.14 12.1 0.0 1.7 1 0 0 1 1 1 0 Myosin-binding striated muscle assembly central NUC173 PF08161.12 OQS05562.1 - 0.12 12.1 0.2 2.5 7.7 0.0 3.3 4 1 0 4 4 4 0 NUC173 domain SEEEED PF14797.6 OQS05562.1 - 1.9 8.7 13.0 4 7.6 13.0 1.5 1 0 0 1 1 1 0 Serine-rich region of AP3B1, clathrin-adaptor complex Glucan_synthase PF02364.15 OQS05563.1 - 7.7e-75 252.6 13.6 2.8e-56 191.2 0.5 4.3 2 1 1 3 3 3 3 1,3-beta-glucan synthase component FKS1_dom1 PF14288.6 OQS05563.1 - 4.9e-32 111.0 0.2 2.1e-31 108.9 0.2 2.2 1 1 0 1 1 1 1 1,3-beta-glucan synthase subunit FKS1, domain-1 STIMATE PF12400.8 OQS05564.1 - 2.7e-70 234.7 24.8 5.5e-36 123.9 8.9 2.7 3 0 0 3 3 3 2 STIMATE family DUF3018 PF11455.8 OQS05564.1 - 0.044 13.7 0.0 16 5.5 0.0 3.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3018) Myosin_head PF00063.21 OQS05565.1 - 2.1e-217 723.5 1.8 3.2e-217 723.0 1.8 1.3 1 0 0 1 1 1 1 Myosin head (motor domain) CBS PF00571.28 OQS05565.1 - 1.1e-119 390.9 64.2 6.2e-07 29.8 0.0 21.1 21 0 0 21 21 21 20 CBS domain ATP-synt_C PF00137.21 OQS05565.1 - 6.1e-31 106.5 41.1 2.6e-21 75.7 16.2 3.3 3 0 0 3 3 3 2 ATP synthase subunit C PB1 PF00564.24 OQS05565.1 - 4.6e-09 36.1 0.1 1.3e-08 34.7 0.1 1.8 1 0 0 1 1 1 1 PB1 domain HlyD_2 PF12700.7 OQS05565.1 - 0.00011 21.1 8.0 0.077 11.7 0.2 3.1 1 1 2 3 3 3 3 HlyD family secretion protein IQ PF00612.27 OQS05565.1 - 0.0017 18.0 17.2 0.043 13.6 1.3 3.8 3 0 0 3 3 3 2 IQ calmodulin-binding motif DUF1192 PF06698.11 OQS05565.1 - 0.0067 16.5 0.8 0.0067 16.5 0.8 3.6 4 0 0 4 4 4 1 Protein of unknown function (DUF1192) bZIP_1 PF00170.21 OQS05565.1 - 0.02 15.0 2.5 0.086 12.9 2.5 2.2 1 0 0 1 1 1 0 bZIP transcription factor AAA_16 PF13191.6 OQS05565.1 - 0.045 14.1 1.3 0.18 12.2 0.0 2.7 2 0 0 2 2 2 0 AAA ATPase domain DUF885 PF05960.11 OQS05565.1 - 6.5 6.3 14.0 4.7 6.7 8.8 2.6 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF885) PrgU PF09627.10 OQS05566.1 - 0.11 12.5 0.0 0.26 11.3 0.0 1.5 1 0 0 1 1 1 0 PrgU-like protein MRNIP PF15749.5 OQS05566.1 - 7.3 7.4 7.5 0.51 11.1 1.3 2.2 2 1 0 2 2 2 0 MRN-interacting protein FYVE PF01363.21 OQS05567.1 - 6.3e-16 58.3 10.5 6.3e-16 58.3 10.5 1.7 2 0 0 2 2 2 1 FYVE zinc finger PH PF00169.29 OQS05567.1 - 9.5e-10 38.9 0.1 1.7e-09 38.1 0.1 1.4 1 0 0 1 1 1 1 PH domain ACBP PF00887.19 OQS05567.1 - 1.4e-06 28.4 0.1 3.3e-06 27.2 0.1 1.6 1 0 0 1 1 1 1 Acyl CoA binding protein FYVE_2 PF02318.16 OQS05567.1 - 0.011 15.9 5.5 0.011 15.9 5.5 1.7 2 0 0 2 2 2 0 FYVE-type zinc finger COPI_assoc PF08507.10 OQS05568.1 - 6.4e-17 61.8 7.8 7.8e-17 61.6 7.8 1.2 1 0 0 1 1 1 1 COPI associated protein DUF4383 PF14325.6 OQS05568.1 - 0.0044 17.3 0.3 0.016 15.5 0.1 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4383) RRM_1 PF00076.22 OQS05569.1 - 3.6e-84 276.6 0.1 1.8e-21 75.7 0.0 4.3 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.18 OQS05569.1 - 3.6e-29 100.7 0.4 7e-28 96.6 0.3 2.4 2 0 0 2 2 2 1 Poly-adenylate binding protein, unique domain RRM_5 PF13893.6 OQS05569.1 - 4e-08 32.9 0.0 0.061 12.9 0.0 3.4 2 1 1 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 OQS05569.1 - 3.4e-06 27.0 0.1 1.2 9.2 0.0 4.3 4 0 0 4 4 4 1 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.11 OQS05569.1 - 0.00062 19.8 0.1 7.8 6.6 0.1 4.1 4 0 0 4 4 4 1 RNA binding motif RRM_7 PF16367.5 OQS05569.1 - 0.00097 19.2 0.0 11 6.2 0.0 4.0 3 1 0 3 3 3 2 RNA recognition motif SET_assoc PF11767.8 OQS05569.1 - 0.0049 16.5 0.2 8 6.2 0.0 3.6 4 0 0 4 4 4 1 Histone lysine methyltransferase SET associated DUF4523 PF15023.6 OQS05569.1 - 0.021 14.7 0.0 6.8 6.5 0.0 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF4523) OB_RNB PF08206.11 OQS05569.1 - 0.49 10.1 2.1 34 4.2 0.2 3.3 3 0 0 3 3 3 0 Ribonuclease B OB domain Tecti-min-caps PF09300.10 OQS05570.1 - 0.05 13.7 0.0 0.076 13.1 0.0 1.3 1 0 0 1 1 1 0 Tectiviridae, minor capsid TPR_19 PF14559.6 OQS05571.1 - 1.8e-06 28.4 19.4 0.0014 19.1 0.2 6.4 7 1 0 7 7 6 2 Tetratricopeptide repeat TPR_14 PF13428.6 OQS05571.1 - 3.5e-06 27.4 13.1 0.7 10.9 0.4 6.8 7 1 1 8 8 7 2 Tetratricopeptide repeat HrpB1_HrpK PF09613.10 OQS05571.1 - 0.00013 21.6 4.8 0.35 10.5 0.1 5.2 5 1 1 6 6 6 1 Bacterial type III secretion protein (HrpB1_HrpK) TPR_2 PF07719.17 OQS05571.1 - 0.00049 20.0 30.4 0.0086 16.1 1.3 7.7 8 0 0 8 8 8 2 Tetratricopeptide repeat ANAPC3 PF12895.7 OQS05571.1 - 0.0048 17.1 40.1 0.051 13.8 0.2 6.7 6 2 0 6 6 6 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.6 OQS05571.1 - 0.0085 16.4 18.0 0.77 10.1 0.7 5.7 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_1 PF00515.28 OQS05571.1 - 0.017 14.9 1.7 0.017 14.9 1.7 6.0 6 1 0 6 6 6 0 Tetratricopeptide repeat TPR_9 PF13371.6 OQS05571.1 - 0.021 14.9 5.7 8.7 6.6 0.0 4.5 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_7 PF13176.6 OQS05571.1 - 0.046 13.8 10.5 8.8 6.6 0.6 5.1 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_16 PF13432.6 OQS05571.1 - 0.17 12.6 8.3 0.19 12.4 0.6 3.4 3 0 0 3 3 2 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 OQS05571.1 - 1.5 9.0 8.7 0.36 10.9 0.7 3.8 3 1 0 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat TPR_6 PF13174.6 OQS05571.1 - 2.8 8.8 17.2 4.9 8.0 0.2 6.3 6 0 0 6 6 5 0 Tetratricopeptide repeat DEAD PF00270.29 OQS05572.1 - 1e-48 165.5 0.0 2.9e-48 163.9 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OQS05572.1 - 4.3e-24 85.0 0.0 2e-23 82.8 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain FYVE PF01363.21 OQS05572.1 - 5.4e-16 58.5 9.3 1.2e-15 57.4 9.3 1.5 1 0 0 1 1 1 1 FYVE zinc finger FIST_C PF10442.9 OQS05572.1 - 1.3e-10 41.4 0.0 3.1e-10 40.1 0.0 1.7 1 0 0 1 1 1 1 FIST C domain FIST PF08495.10 OQS05572.1 - 3.4e-09 36.9 0.1 9.6e-09 35.5 0.1 1.8 1 0 0 1 1 1 1 FIST N domain C1_1 PF00130.22 OQS05572.1 - 0.015 15.2 2.8 0.031 14.2 2.8 1.5 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-B_box PF00643.24 OQS05572.1 - 0.33 11.1 3.0 0.88 9.8 3.0 1.7 1 0 0 1 1 1 0 B-box zinc finger EnY2 PF10163.9 OQS05573.1 - 1.6e-33 114.9 0.9 1.9e-33 114.7 0.9 1.1 1 0 0 1 1 1 1 Transcription factor e(y)2 DUF2262 PF10020.9 OQS05573.1 - 0.069 13.5 0.4 0.074 13.4 0.4 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2262) Glutaredoxin PF00462.24 OQS05574.1 - 2.2e-18 66.2 0.0 3.3e-18 65.7 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin TraF PF13728.6 OQS05574.1 - 0.005 16.7 0.0 0.0059 16.4 0.0 1.1 1 0 0 1 1 1 1 F plasmid transfer operon protein DSBA PF01323.20 OQS05574.1 - 0.012 15.4 0.2 0.56 9.9 0.0 2.1 1 1 1 2 2 2 0 DSBA-like thioredoxin domain DUF836 PF05768.14 OQS05574.1 - 0.013 15.9 0.0 0.018 15.4 0.0 1.3 1 1 0 1 1 1 0 Glutaredoxin-like domain (DUF836) Thioredoxin PF00085.20 OQS05574.1 - 0.023 14.7 0.0 0.023 14.7 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin Thioredoxin_2 PF13098.6 OQS05574.1 - 0.042 14.3 0.1 0.064 13.7 0.1 1.5 1 1 0 1 1 1 0 Thioredoxin-like domain Hydrolase_4 PF12146.8 OQS05574.1 - 0.072 12.3 0.0 0.083 12.1 0.0 1.2 1 0 0 1 1 1 0 Serine aminopeptidase, S33 DNA_ligase_A_N PF04675.14 OQS05575.1 - 2.5e-35 122.3 0.3 4.9e-35 121.4 0.3 1.5 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_M PF01068.21 OQS05575.1 - 2.3e-32 112.3 0.0 4.4e-32 111.4 0.0 1.5 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_C PF04679.15 OQS05575.1 - 3.1e-19 69.4 0.0 1.6e-18 67.1 0.0 2.3 2 0 0 2 2 2 1 ATP dependent DNA ligase C terminal region BRCT_2 PF16589.5 OQS05575.1 - 6.5e-18 64.9 0.1 5.3e-09 36.4 0.0 2.5 2 0 0 2 2 2 2 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 OQS05575.1 - 1.7e-16 60.3 0.1 2.6e-08 34.1 0.1 2.8 2 0 0 2 2 2 2 BRCA1 C Terminus (BRCT) domain LIG3_BRCT PF16759.5 OQS05575.1 - 2e-06 28.0 0.3 0.0012 19.1 0.0 3.0 3 0 0 3 3 3 2 DNA ligase 3 BRCT domain PTCB-BRCT PF12738.7 OQS05575.1 - 0.00019 21.3 0.0 0.24 11.4 0.0 2.8 2 0 0 2 2 2 2 twin BRCT domain DNA_ligase_IV PF11411.8 OQS05575.1 - 0.0029 17.7 0.2 0.0099 16.0 0.1 2.0 2 0 0 2 2 2 1 DNA ligase IV bZIP_2 PF07716.15 OQS05576.1 - 8.7e-09 35.3 11.9 1.5e-08 34.5 11.9 1.4 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 OQS05576.1 - 4.3e-07 29.9 11.2 8e-07 29.1 11.2 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_Maf PF03131.17 OQS05576.1 - 0.00022 21.7 5.8 0.00044 20.7 5.8 1.6 1 0 0 1 1 1 1 bZIP Maf transcription factor SnoaL PF07366.12 OQS05576.1 - 0.00056 19.7 0.0 0.00097 18.9 0.0 1.4 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase Cep57_CLD PF14073.6 OQS05576.1 - 0.0076 16.3 2.5 0.011 15.7 2.5 1.2 1 0 0 1 1 1 1 Centrosome localisation domain of Cep57 SnoaL_2 PF12680.7 OQS05576.1 - 0.017 15.7 0.0 0.04 14.6 0.0 1.6 1 0 0 1 1 1 0 SnoaL-like domain LCD1 PF09798.9 OQS05576.1 - 0.054 12.0 0.6 0.067 11.7 0.6 1.1 1 0 0 1 1 1 0 DNA damage checkpoint protein DUF1465 PF07323.12 OQS05576.1 - 0.2 11.5 5.2 0.19 11.6 3.8 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1465) MCM PF00493.23 OQS05577.1 - 1.4e-103 344.8 0.1 2.3e-103 344.1 0.1 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 OQS05577.1 - 2.9e-36 124.1 1.5 1.6e-35 121.7 0.1 2.4 2 0 0 2 2 2 1 MCM OB domain MCM_lid PF17855.1 OQS05577.1 - 5.8e-25 87.5 1.9 1.7e-24 86.0 1.9 1.9 1 0 0 1 1 1 1 MCM AAA-lid domain MCM6_C PF18263.1 OQS05577.1 - 1.9e-17 63.5 0.3 1.9e-17 63.5 0.3 3.1 3 0 0 3 3 3 1 MCM6 C-terminal winged-helix domain Mg_chelatase PF01078.21 OQS05577.1 - 5.1e-09 35.8 0.0 4.8e-08 32.6 0.0 2.4 1 1 0 1 1 1 1 Magnesium chelatase, subunit ChlI MCM_N PF14551.6 OQS05577.1 - 6.5e-05 23.5 0.0 0.00029 21.4 0.0 2.2 1 0 0 1 1 1 1 MCM N-terminal domain AAA_5 PF07728.14 OQS05577.1 - 0.00035 20.6 0.0 0.0014 18.7 0.0 2.1 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.26 OQS05577.1 - 0.0032 17.2 0.0 0.0086 15.8 0.0 1.7 1 0 0 1 1 1 1 Sigma-54 interaction domain Mg_chelatase_C PF13335.6 OQS05577.1 - 0.0061 17.2 1.4 1.3 9.7 0.2 3.3 2 1 1 3 3 3 1 Magnesium chelatase, subunit ChlI C-terminal AAA_3 PF07726.11 OQS05577.1 - 0.0096 15.8 0.0 0.022 14.6 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) zf-FPG_IleRS PF06827.14 OQS05577.1 - 0.2 11.6 4.7 0.21 11.5 0.9 2.8 2 0 0 2 2 2 0 Zinc finger found in FPG and IleRS zinc-ribbons_6 PF07191.12 OQS05577.1 - 0.34 10.9 9.7 0.018 15.0 1.9 2.5 1 1 1 2 2 2 0 zinc-ribbons TF_Zn_Ribbon PF08271.12 OQS05577.1 - 3.6 7.2 11.8 0.79 9.3 1.4 3.5 3 0 0 3 3 3 0 TFIIB zinc-binding DZR PF12773.7 OQS05577.1 - 5 7.2 5.8 9.9 6.3 1.0 2.9 2 0 0 2 2 2 0 Double zinc ribbon MscS_porin PF12795.7 OQS05578.1 - 6.7e-05 22.5 28.4 6.7e-05 22.5 28.4 2.3 1 1 1 2 2 2 1 Mechanosensitive ion channel porin domain IFT57 PF10498.9 OQS05578.1 - 0.00037 19.6 20.1 0.00037 19.6 20.1 2.1 1 1 1 2 2 2 1 Intra-flagellar transport protein 57 Fez1 PF06818.15 OQS05578.1 - 0.0092 16.4 35.5 0.017 15.6 5.5 3.1 1 1 2 3 3 3 1 Fez1 DUF16 PF01519.16 OQS05578.1 - 0.0099 16.3 3.9 0.0099 16.3 3.9 3.4 1 1 1 2 2 1 1 Protein of unknown function DUF16 DUF3145 PF11343.8 OQS05578.1 - 0.01 15.4 0.7 0.021 14.4 0.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3145) DUF725 PF05267.12 OQS05578.1 - 0.02 14.8 0.7 0.02 14.8 0.7 3.3 1 1 1 3 3 3 0 Protein of unknown function (DUF725) bZIP_Maf PF03131.17 OQS05578.1 - 0.023 15.2 2.5 0.023 15.2 2.5 4.2 2 2 2 4 4 4 0 bZIP Maf transcription factor ATG16 PF08614.11 OQS05578.1 - 0.077 13.2 42.8 0.97 9.6 23.0 3.1 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) GAS PF13851.6 OQS05578.1 - 0.093 12.1 39.6 0.37 10.1 19.9 2.5 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Golgin_A5 PF09787.9 OQS05578.1 - 0.11 11.9 37.4 0.014 14.9 24.1 2.2 1 1 1 2 2 2 0 Golgin subfamily A member 5 Filament PF00038.21 OQS05578.1 - 0.36 10.4 37.4 1 8.9 6.6 3.1 1 1 2 3 3 3 0 Intermediate filament protein TPR_MLP1_2 PF07926.12 OQS05578.1 - 0.37 10.8 45.5 4.9 7.2 16.2 3.1 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein DUF3584 PF12128.8 OQS05578.1 - 0.43 8.0 34.6 0.54 7.7 34.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF1192 PF06698.11 OQS05578.1 - 0.51 10.4 9.7 1.7e+02 2.3 0.0 3.9 2 1 0 2 2 2 0 Protein of unknown function (DUF1192) NERD PF08378.11 OQS05578.1 - 0.63 10.5 2.6 30 5.1 0.1 2.6 2 0 0 2 2 2 0 Nuclease-related domain DUF1664 PF07889.12 OQS05578.1 - 0.9 9.6 25.1 0.21 11.6 4.2 3.5 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) Spc29 PF17082.5 OQS05578.1 - 0.96 9.2 21.0 6.1 6.6 7.3 2.7 1 1 1 2 2 2 0 Spindle Pole Component 29 HIP1_clath_bdg PF16515.5 OQS05578.1 - 1.2 9.8 39.8 2.2 8.9 1.5 4.6 1 1 3 4 4 4 0 Clathrin-binding domain of Huntingtin-interacting protein 1 TMF_TATA_bd PF12325.8 OQS05578.1 - 1.3 9.3 36.4 0.74 10.0 11.3 3.4 1 1 1 3 3 3 0 TATA element modulatory factor 1 TATA binding APG6_N PF17675.1 OQS05578.1 - 1.4 9.5 45.7 0.036 14.6 14.0 3.7 1 1 2 3 3 3 0 Apg6 coiled-coil region Spc7 PF08317.11 OQS05578.1 - 1.5 7.6 39.2 0.73 8.7 19.9 2.9 1 1 2 3 3 3 0 Spc7 kinetochore protein DUF4201 PF13870.6 OQS05578.1 - 2.4 7.8 28.2 0.018 14.8 10.2 3.0 1 1 2 3 3 3 0 Domain of unknown function (DUF4201) FlaC_arch PF05377.11 OQS05578.1 - 3.3 8.2 18.1 1.5 9.3 0.7 5.0 3 1 1 4 4 4 0 Flagella accessory protein C (FlaC) Prominin PF05478.11 OQS05578.1 - 3.6 5.4 25.5 0.81 7.6 9.8 2.2 1 1 1 2 2 2 0 Prominin Fzo_mitofusin PF04799.13 OQS05578.1 - 5.4 6.5 24.6 0.14 11.7 3.5 3.4 1 1 0 3 3 3 0 fzo-like conserved region FapA PF03961.13 OQS05578.1 - 5.5 5.5 20.9 1.2 7.6 7.4 2.5 1 1 2 3 3 3 0 Flagellar Assembly Protein A DUF5082 PF16888.5 OQS05578.1 - 6 7.2 30.4 16 5.8 14.7 3.9 2 2 0 2 2 2 0 Domain of unknown function (DUF5082) Fib_alpha PF08702.10 OQS05578.1 - 7.2 6.8 25.7 0.9 9.7 7.8 3.4 1 1 3 4 4 4 0 Fibrinogen alpha/beta chain family DUF4192 PF13830.6 OQS05578.1 - 8.7 6.3 13.3 0.33 10.9 1.5 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4192) TSC22 PF01166.18 OQS05578.1 - 9.7 6.6 16.9 0.55 10.6 0.8 4.6 2 2 1 4 4 4 0 TSC-22/dip/bun family LRR_4 PF12799.7 OQS05579.1 - 1.6e-28 98.3 46.5 1.4e-08 34.9 0.9 6.8 5 1 2 7 7 7 6 Leucine Rich repeats (2 copies) PH PF00169.29 OQS05579.1 - 4e-25 88.3 1.0 9.5e-07 29.3 0.1 4.7 4 0 0 4 4 4 4 PH domain LRR_8 PF13855.6 OQS05579.1 - 3.3e-16 58.8 42.3 1.7e-05 24.4 2.4 5.8 2 2 4 6 6 6 6 Leucine rich repeat LRR_9 PF14580.6 OQS05579.1 - 3.7e-15 55.9 24.4 4.9e-09 35.9 7.5 3.8 1 1 2 3 3 3 3 Leucine-rich repeat PUB PF09409.10 OQS05579.1 - 7.5e-12 45.0 0.0 2.3e-11 43.5 0.0 1.8 1 0 0 1 1 1 1 PUB domain PH_9 PF15410.6 OQS05579.1 - 0.0026 18.1 1.3 1.8 8.9 0.0 4.5 4 1 0 4 4 4 1 Pleckstrin homology domain PH_11 PF15413.6 OQS05579.1 - 0.095 13.1 8.4 7.8 7.0 0.1 5.0 5 1 0 5 5 5 0 Pleckstrin homology domain LRR_1 PF00560.33 OQS05579.1 - 0.98 10.2 30.2 16 6.5 0.2 9.2 9 0 0 9 9 9 0 Leucine Rich Repeat LRR_6 PF13516.6 OQS05579.1 - 2.4 8.5 31.0 7.8 6.8 0.2 8.9 9 0 0 9 9 9 0 Leucine Rich repeat IQ PF00612.27 OQS05580.1 - 2.8e-15 54.6 52.1 0.00023 20.7 0.1 8.9 8 0 0 8 8 8 8 IQ calmodulin-binding motif WW PF00397.26 OQS05580.1 - 7.4e-12 45.1 5.8 1.4e-06 28.2 1.0 2.5 2 0 0 2 2 2 2 WW domain zf-B_box PF00643.24 OQS05580.1 - 2.3e-08 34.0 15.5 0.00042 20.4 4.7 2.5 2 0 0 2 2 2 2 B-box zinc finger CEBP_ZZ PF16366.5 OQS05580.1 - 0.025 14.8 21.9 0.45 10.8 7.1 2.8 1 1 1 2 2 2 0 Cytoplasmic polyadenylation element-binding protein ZZ domain C1_4 PF07975.12 OQS05580.1 - 3.1 8.1 11.2 4.2 7.7 1.8 2.9 2 0 0 2 2 2 0 TFIIH C1-like domain FCH PF00611.23 OQS05581.1 - 0.0019 18.5 1.4 0.018 15.3 0.1 3.0 3 0 0 3 3 3 1 Fes/CIP4, and EFC/F-BAR homology domain DUF29 PF01724.16 OQS05581.1 - 0.0086 16.3 1.2 0.037 14.3 0.2 2.2 2 0 0 2 2 2 1 Domain of unknown function DUF29 BAR_3 PF16746.5 OQS05581.1 - 0.012 15.3 3.2 0.032 13.9 3.2 1.6 1 0 0 1 1 1 0 BAR domain of APPL family TMPIT PF07851.13 OQS05581.1 - 0.18 11.0 3.0 0.35 10.1 3.0 1.4 1 0 0 1 1 1 0 TMPIT-like protein PX PF00787.24 OQS05583.1 - 8.9e-17 61.1 0.0 3.5e-16 59.2 0.0 2.0 2 0 0 2 2 2 1 PX domain Peptidase_C92 PF05708.12 OQS05583.1 - 3.9e-08 33.6 0.0 1.2e-07 32.0 0.0 1.9 1 0 0 1 1 1 1 Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family PH PF00169.29 OQS05583.1 - 0.00049 20.6 1.0 0.0025 18.3 0.7 2.4 2 1 0 2 2 2 1 PH domain Pkinase PF00069.25 OQS05585.1 - 2.2e-63 214.1 0.0 1.3e-62 211.6 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQS05585.1 - 1.1e-32 113.4 0.0 3.9e-26 91.9 0.0 2.4 1 1 1 2 2 2 2 Protein tyrosine kinase PAS PF00989.25 OQS05585.1 - 1.4e-07 31.5 0.0 4.5e-07 29.9 0.0 1.9 1 0 0 1 1 1 1 PAS fold PAS_9 PF13426.7 OQS05585.1 - 4.6e-06 26.8 0.0 1.5e-05 25.2 0.0 1.9 2 0 0 2 2 2 1 PAS domain Kdo PF06293.14 OQS05585.1 - 2.1e-05 24.0 0.1 0.00011 21.7 0.1 1.9 1 1 1 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family PAS_4 PF08448.10 OQS05585.1 - 0.00011 22.4 0.0 0.00027 21.2 0.0 1.7 1 0 0 1 1 1 1 PAS fold RIO1 PF01163.22 OQS05585.1 - 0.00059 19.5 0.3 0.0031 17.1 0.0 2.0 2 0 0 2 2 2 1 RIO1 family APH PF01636.23 OQS05585.1 - 0.0011 18.9 0.4 0.014 15.4 0.1 2.6 2 1 1 3 3 3 1 Phosphotransferase enzyme family PAS_8 PF13188.7 OQS05585.1 - 0.0032 17.4 0.0 0.0087 16.1 0.0 1.8 1 0 0 1 1 1 1 PAS domain Rz1 PF06085.11 OQS05585.1 - 0.053 13.3 0.0 0.17 11.6 0.0 1.9 1 0 0 1 1 1 0 Lipoprotein Rz1 precursor NAD_binding_6 PF08030.12 OQS05586.1 - 7.5e-34 117.1 0.0 1.6e-33 116.1 0.0 1.6 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 OQS05586.1 - 3.2e-21 75.4 0.0 8e-21 74.2 0.0 1.7 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.19 OQS05586.1 - 6.9e-16 58.5 6.2 1.4e-15 57.6 6.2 1.5 1 0 0 1 1 1 1 Ferric reductase like transmembrane component EF-hand_7 PF13499.6 OQS05586.1 - 0.00021 21.7 0.4 0.00068 20.0 0.4 2.0 1 0 0 1 1 1 1 EF-hand domain pair NAD_binding_1 PF00175.21 OQS05586.1 - 0.0017 19.0 0.0 0.009 16.6 0.0 2.2 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain EF-hand_6 PF13405.6 OQS05586.1 - 0.0023 17.7 1.5 0.0073 16.2 0.3 2.5 2 0 0 2 2 2 1 EF-hand domain EF-hand_1 PF00036.32 OQS05586.1 - 0.0024 17.3 0.1 0.022 14.3 0.1 2.6 2 0 0 2 2 2 1 EF hand Glyco_hydro_72 PF03198.14 OQS05587.1 - 3.1e-36 125.2 5.5 2.9e-35 122.0 5.5 2.1 1 1 0 1 1 1 1 Glucanosyltransferase MORN PF02493.20 OQS05587.1 - 0.00014 21.5 8.6 0.00085 19.1 1.8 3.7 4 0 0 4 4 4 2 MORN repeat Glyco_trans_1_2 PF13524.6 OQS05587.1 - 0.18 12.2 0.1 0.58 10.6 0.1 1.9 1 0 0 1 1 1 0 Glycosyl transferases group 1 EGF_2 PF07974.13 OQS05587.1 - 3.6 8.0 28.0 1.8 9.0 19.5 3.4 2 1 1 3 3 3 0 EGF-like domain TPH PF13868.6 OQS05588.1 - 2e-19 69.3 136.8 2e-19 69.3 136.8 2.1 2 0 0 2 2 2 1 Trichohyalin-plectin-homology domain CHORD PF04968.12 OQS05589.1 - 2.5e-38 130.6 30.7 2.9e-20 72.7 5.3 2.9 3 0 0 3 3 3 2 CHORD LRR_4 PF12799.7 OQS05589.1 - 1.5e-17 63.4 21.0 3.7e-06 27.2 4.5 4.7 3 1 0 4 4 4 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 OQS05589.1 - 6.7e-10 38.6 25.0 6.1e-05 22.7 4.2 4.0 2 2 0 3 3 3 3 Leucine rich repeat LRR_9 PF14580.6 OQS05589.1 - 1.9e-09 37.3 2.7 0.00013 21.5 0.0 2.4 1 1 1 2 2 2 2 Leucine-rich repeat IQ PF00612.27 OQS05589.1 - 0.0013 18.4 1.1 0.0093 15.7 0.2 2.5 2 0 0 2 2 2 1 IQ calmodulin-binding motif LRR_6 PF13516.6 OQS05589.1 - 0.008 16.1 21.0 0.71 10.1 0.7 6.7 5 1 1 6 6 6 1 Leucine Rich repeat Cas3_C PF18395.1 OQS05589.1 - 0.015 15.8 2.5 1.9 9.0 0.3 2.6 2 0 0 2 2 2 0 Cas3 C-terminal domain BTK PF00779.19 OQS05589.1 - 0.016 15.0 4.5 1.6 8.6 0.2 2.7 2 0 0 2 2 2 0 BTK motif PHB_acc PF05233.13 OQS05589.1 - 0.17 12.0 0.0 0.17 12.0 0.0 1.9 2 0 0 2 2 2 0 PHB accumulation regulatory domain TPR_10 PF13374.6 OQS05590.1 - 1.9e-80 262.8 14.8 1.2e-10 40.9 0.4 10.2 10 0 0 10 10 10 10 Tetratricopeptide repeat TPR_12 PF13424.6 OQS05590.1 - 1.3e-68 227.3 20.8 7.9e-15 54.9 3.5 6.6 3 1 3 7 7 7 7 Tetratricopeptide repeat TPR_7 PF13176.6 OQS05590.1 - 1.6e-19 68.4 19.3 0.0027 17.6 0.1 9.0 10 0 0 10 10 9 5 Tetratricopeptide repeat TPR_2 PF07719.17 OQS05590.1 - 5.1e-16 57.4 29.8 0.072 13.2 0.4 9.8 10 0 0 10 10 10 7 Tetratricopeptide repeat TPR_8 PF13181.6 OQS05590.1 - 8.1e-16 56.8 34.8 0.0011 19.0 0.1 9.3 10 0 0 10 10 9 4 Tetratricopeptide repeat TPR_1 PF00515.28 OQS05590.1 - 1.3e-13 50.1 42.2 0.021 14.6 0.2 9.4 10 0 0 10 10 10 6 Tetratricopeptide repeat TPR_MalT PF17874.1 OQS05590.1 - 1.1e-09 38.2 13.1 0.00023 20.6 1.2 3.1 1 1 1 3 3 3 3 MalT-like TPR region TPR_4 PF07721.14 OQS05590.1 - 5.9e-07 29.5 0.0 1.4 9.8 0.0 6.3 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_14 PF13428.6 OQS05590.1 - 2e-05 25.0 9.4 15 6.7 0.1 8.5 10 0 0 10 10 9 0 Tetratricopeptide repeat TPR_16 PF13432.6 OQS05590.1 - 2.3e-05 25.0 14.5 10 6.9 0.2 7.8 6 2 1 7 7 7 1 Tetratricopeptide repeat TPR_19 PF14559.6 OQS05590.1 - 5.6e-05 23.6 19.1 0.1 13.2 0.1 5.9 4 2 2 6 6 6 3 Tetratricopeptide repeat RPN6_N PF18055.1 OQS05590.1 - 8.7e-05 22.9 6.0 2.7 8.4 0.1 4.8 3 1 2 5 5 5 2 26S proteasome regulatory subunit RPN6 N-terminal domain TPR_6 PF13174.6 OQS05590.1 - 0.031 14.9 17.6 4.9 8.0 0.2 7.0 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_17 PF13431.6 OQS05590.1 - 0.13 12.7 28.3 0.88 10.1 0.2 7.9 9 1 0 9 9 8 0 Tetratricopeptide repeat 3H PF02829.14 OQS05590.1 - 0.16 12.3 0.0 1 9.7 0.0 2.4 1 1 1 2 2 2 0 3H domain TPR_20 PF14561.6 OQS05590.1 - 2.9 8.3 12.7 21 5.5 0.0 6.7 7 2 1 9 9 9 0 Tetratricopeptide repeat DUF4398 PF14346.6 OQS05591.1 - 0.0048 17.5 7.5 0.011 16.3 7.5 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4398) TBCA PF02970.16 OQS05591.1 - 0.014 15.7 4.7 0.014 15.7 4.7 2.2 2 0 0 2 2 2 0 Tubulin binding cofactor A DUF2379 PF09543.10 OQS05591.1 - 0.098 12.8 6.1 0.08 13.1 3.3 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2379) TPR_MLP1_2 PF07926.12 OQS05591.1 - 0.14 12.2 19.5 0.36 10.9 11.5 2.5 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein DUF2564 PF10819.8 OQS05591.1 - 0.16 12.4 5.3 0.7 10.3 4.8 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2564) KxDL PF10241.9 OQS05591.1 - 0.17 12.2 4.7 0.072 13.4 1.3 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein SMBP PF16785.5 OQS05591.1 - 0.59 10.4 6.2 0.27 11.5 3.1 1.9 2 0 0 2 2 2 0 Small metal-binding protein DUF4140 PF13600.6 OQS05591.1 - 8.3 6.9 8.1 14 6.2 4.2 2.7 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) Atg14 PF10186.9 OQS05591.1 - 8.4 5.4 11.6 13 4.8 11.6 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF4537 PF15057.6 OQS05593.1 - 0.00036 20.5 0.1 0.26 11.3 0.0 3.5 1 1 2 3 3 3 2 Domain of unknown function (DUF4537) LBR_tudor PF09465.10 OQS05593.1 - 0.046 13.5 0.3 4.6 7.1 0.0 3.2 3 0 0 3 3 3 0 Lamin-B receptor of TUDOR domain Erf4 PF10256.9 OQS05593.1 - 0.071 13.2 0.3 6.6 6.9 0.2 2.6 2 0 0 2 2 2 0 Golgin subfamily A member 7/ERF4 family bZIP_1 PF00170.21 OQS05594.1 - 3.9e-06 26.9 13.4 0.0052 16.8 0.9 2.4 2 0 0 2 2 2 2 bZIP transcription factor bZIP_2 PF07716.15 OQS05594.1 - 0.0036 17.3 20.4 0.0088 16.1 0.9 2.6 3 0 0 3 3 3 2 Basic region leucine zipper Bestrophin PF01062.21 OQS05595.1 - 1.1e-22 80.8 2.4 1.5e-22 80.4 2.4 1.1 1 0 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel Ribonuclease_T2 PF00445.18 OQS05596.1 - 1.1e-27 97.4 2.1 1.5e-27 97.0 2.1 1.1 1 0 0 1 1 1 1 Ribonuclease T2 family Endonuclease_NS PF01223.23 OQS05597.1 - 0.0023 17.8 0.0 0.004 17.0 0.0 1.3 1 0 0 1 1 1 1 DNA/RNA non-specific endonuclease FYVE PF01363.21 OQS05598.1 - 8.3e-05 22.6 9.1 0.00018 21.6 9.1 1.5 1 0 0 1 1 1 1 FYVE zinc finger DZR PF12773.7 OQS05598.1 - 0.3 11.2 13.4 0.2 11.7 8.6 2.7 2 1 1 3 3 3 0 Double zinc ribbon zinc-ribbons_6 PF07191.12 OQS05598.1 - 0.33 11.0 9.1 7.8 6.6 7.8 2.8 2 1 0 2 2 2 0 zinc-ribbons zf-B_box PF00643.24 OQS05598.1 - 6.6 7.0 13.2 3.3 7.9 8.9 2.6 2 1 0 2 2 2 0 B-box zinc finger Endonuclease_NS PF01223.23 OQS05599.1 - 4.8e-31 108.3 0.1 6.1e-31 108.0 0.1 1.0 1 0 0 1 1 1 1 DNA/RNA non-specific endonuclease Endonuclea_NS_2 PF13930.6 OQS05599.1 - 0.0013 18.8 0.5 0.0031 17.6 0.5 1.5 1 1 0 1 1 1 1 DNA/RNA non-specific endonuclease Glyco_transf_41 PF13844.6 OQS05600.1 - 4.5e-134 447.4 3.5 2.9e-73 246.9 0.0 2.1 1 1 1 2 2 2 2 Glycosyl transferase family 41 TPR_11 PF13414.6 OQS05600.1 - 3.1e-105 343.6 31.7 6.6e-13 48.1 0.4 12.1 3 3 9 12 12 12 11 TPR repeat TPR_1 PF00515.28 OQS05600.1 - 8.1e-98 316.6 38.0 9.4e-10 37.9 0.7 12.8 13 0 0 13 13 12 12 Tetratricopeptide repeat TPR_8 PF13181.6 OQS05600.1 - 9.4e-75 240.7 20.2 5.9e-07 29.2 0.0 12.6 12 0 0 12 12 12 12 Tetratricopeptide repeat TPR_2 PF07719.17 OQS05600.1 - 3.3e-74 239.2 34.0 3.1e-07 30.0 0.8 13.2 13 0 0 13 13 13 12 Tetratricopeptide repeat TPR_17 PF13431.6 OQS05600.1 - 4.5e-59 192.7 26.8 1.4e-07 31.4 0.2 12.6 12 0 0 12 12 12 10 Tetratricopeptide repeat TPR_7 PF13176.6 OQS05600.1 - 6.2e-51 166.7 16.2 5.7e-05 22.9 0.0 13.5 13 0 0 13 13 13 10 Tetratricopeptide repeat TPR_12 PF13424.6 OQS05600.1 - 4.7e-41 138.9 31.3 4.8e-10 39.6 0.8 9.1 5 3 3 8 8 8 7 Tetratricopeptide repeat TPR_14 PF13428.6 OQS05600.1 - 2.6e-38 127.4 12.7 0.0004 21.0 0.0 12.9 3 2 11 14 14 13 8 Tetratricopeptide repeat TPR_16 PF13432.6 OQS05600.1 - 3.4e-38 130.0 18.2 4.6e-08 33.6 2.3 8.3 4 2 4 9 9 9 8 Tetratricopeptide repeat TPR_10 PF13374.6 OQS05600.1 - 1.4e-33 113.8 39.6 3.5e-05 23.5 0.0 11.7 13 0 0 13 13 11 9 Tetratricopeptide repeat TPR_19 PF14559.6 OQS05600.1 - 1.5e-31 108.7 21.0 4.2e-06 27.2 0.1 8.0 4 3 5 9 9 9 8 Tetratricopeptide repeat TPR_6 PF13174.6 OQS05600.1 - 5.9e-18 64.2 15.3 0.38 11.5 0.1 10.8 11 0 0 11 11 10 2 Tetratricopeptide repeat TPR_9 PF13371.6 OQS05600.1 - 2.2e-15 56.5 8.1 0.0021 18.1 0.1 6.7 4 1 3 8 8 8 3 Tetratricopeptide repeat TPR_15 PF13429.6 OQS05600.1 - 1.4e-11 44.1 3.6 0.058 12.6 0.2 5.5 2 2 3 5 5 5 4 Tetratricopeptide repeat BTAD PF03704.17 OQS05600.1 - 2.2e-11 44.4 7.9 0.048 14.1 0.1 5.2 3 1 2 5 5 5 4 Bacterial transcriptional activator domain NARP1 PF12569.8 OQS05600.1 - 1.3e-09 37.5 4.7 0.82 8.5 0.0 5.3 1 1 3 5 5 5 4 NMDA receptor-regulated protein 1 TPR_4 PF07721.14 OQS05600.1 - 8e-09 35.3 0.1 0.94 10.3 0.0 5.9 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_MalT PF17874.1 OQS05600.1 - 4e-08 33.0 4.1 0.032 13.6 0.2 4.2 1 1 3 4 4 4 3 MalT-like TPR region FAT PF02259.23 OQS05600.1 - 1e-05 25.0 0.1 1.5 8.0 0.0 5.1 1 1 2 4 4 4 1 FAT domain PPR PF01535.20 OQS05600.1 - 2.5e-05 24.2 11.3 4 7.9 0.0 7.8 8 0 0 8 8 8 2 PPR repeat EST1_DNA_bind PF10373.9 OQS05600.1 - 4.7e-05 23.0 13.6 2 7.8 0.1 5.8 4 2 2 6 6 6 3 Est1 DNA/RNA binding domain TOM20_plant PF06552.12 OQS05600.1 - 4.8e-05 23.2 1.2 0.14 11.9 0.0 4.8 4 2 2 6 6 5 1 Plant specific mitochondrial import receptor subunit TOM20 Wzy_C_2 PF11846.8 OQS05600.1 - 0.00021 21.3 3.3 3.9 7.3 0.0 4.4 3 1 1 4 4 4 1 Virulence factor membrane-bound polymerase, C-terminal SNAP PF14938.6 OQS05600.1 - 0.0039 16.7 17.7 0.56 9.6 0.6 5.0 1 1 3 4 4 4 2 Soluble NSF attachment protein, SNAP TPR_21 PF09976.9 OQS05600.1 - 0.009 15.7 9.4 1.8 8.2 1.5 4.2 2 2 2 4 4 4 1 Tetratricopeptide repeat-like domain DUF5113 PF17140.4 OQS05600.1 - 0.011 15.6 6.5 9.6 6.0 0.0 4.8 4 1 0 5 5 5 0 Domain of unknown function (DUF5113) ANAPC3 PF12895.7 OQS05600.1 - 0.014 15.6 15.3 6.8 7.0 0.2 6.1 4 2 3 7 7 7 0 Anaphase-promoting complex, cyclosome, subunit 3 T2SSF PF00482.23 OQS05600.1 - 0.014 15.4 0.0 0.69 9.9 0.0 3.2 3 0 0 3 3 3 0 Type II secretion system (T2SS), protein F SHNi-TPR PF10516.9 OQS05600.1 - 0.026 14.0 2.2 25 4.4 0.1 5.1 5 0 0 5 5 5 0 SHNi-TPR Fis1_TPR_C PF14853.6 OQS05600.1 - 0.057 13.5 0.1 2.3 8.4 0.0 3.2 3 0 0 3 3 2 0 Fis1 C-terminal tetratricopeptide repeat RPN7 PF10602.9 OQS05600.1 - 0.17 11.6 15.5 18 5.0 0.1 6.6 4 3 3 7 7 7 0 26S proteasome subunit RPN7 Tektin PF03148.14 OQS05600.1 - 0.19 10.4 0.0 0.55 8.9 0.0 1.7 2 0 0 2 2 2 0 Tektin family MIT PF04212.18 OQS05600.1 - 0.38 10.9 24.7 18 5.5 0.3 9.5 7 2 3 11 11 11 0 MIT (microtubule interacting and transport) domain Mad3_BUB1_I PF08311.12 OQS05600.1 - 4.2 7.4 10.3 37 4.3 0.1 5.2 5 0 0 5 5 5 0 Mad3/BUB1 homology region 1 Lyase_1 PF00206.20 OQS05601.1 - 2.1e-22 79.9 0.0 3.3e-22 79.3 0.0 1.3 1 0 0 1 1 1 1 Lyase ADSL_C PF10397.9 OQS05601.1 - 3e-18 66.1 0.1 6.9e-18 65.0 0.1 1.7 1 0 0 1 1 1 1 Adenylosuccinate lyase C-terminus GTP_CH_N PF12471.8 OQS05602.1 - 1.2e-52 178.5 0.1 4.3e-52 176.7 0.0 1.8 2 0 0 2 2 2 1 GTP cyclohydrolase N terminal GTP_cyclohydro2 PF00925.20 OQS05602.1 - 7.1e-17 61.5 0.0 1e-16 61.0 0.0 1.2 1 0 0 1 1 1 1 GTP cyclohydrolase II DnaJ_C PF01556.18 OQS05603.1 - 2.9e-32 111.8 0.2 4e-32 111.3 0.2 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 OQS05603.1 - 6.7e-26 90.2 0.9 1e-25 89.6 0.9 1.3 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 OQS05603.1 - 4.2e-15 55.9 22.1 6.4e-15 55.3 22.1 1.3 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 OQS05603.1 - 2.6e-05 24.1 10.3 0.007 16.3 1.3 2.6 2 0 0 2 2 2 2 Tryptophan RNA-binding attenuator protein inhibitory protein HypA PF01155.19 OQS05603.1 - 0.018 15.1 12.2 0.54 10.3 3.3 2.3 1 1 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA TackOD1 PF18551.1 OQS05603.1 - 0.029 14.0 7.5 0.036 13.7 0.9 2.2 1 1 1 2 2 2 0 Thaumarchaeal output domain 1 CsiD PF08943.10 OQS05603.1 - 0.28 10.3 0.8 0.42 9.7 0.2 1.5 2 0 0 2 2 2 0 CsiD Lar_restr_allev PF14354.6 OQS05603.1 - 0.28 11.6 13.4 3 8.3 0.1 3.9 1 1 1 3 3 3 0 Restriction alleviation protein Lar DZR PF12773.7 OQS05603.1 - 0.7 10.0 11.7 2 8.5 11.8 1.7 1 1 0 1 1 1 0 Double zinc ribbon zinc-ribbons_6 PF07191.12 OQS05603.1 - 1.4 9.0 9.7 5.4 7.1 9.7 1.9 1 1 0 1 1 1 0 zinc-ribbons Ank_2 PF12796.7 OQS05604.1 - 2.3e-19 69.8 5.2 1.5e-11 44.7 1.1 3.4 2 1 2 4 4 4 3 Ankyrin repeats (3 copies) Ank PF00023.30 OQS05604.1 - 5.5e-15 55.0 0.9 0.013 16.0 0.0 5.1 4 1 0 4 4 4 4 Ankyrin repeat FYVE PF01363.21 OQS05604.1 - 6.4e-15 55.1 15.0 1.1e-14 54.2 15.0 1.4 1 0 0 1 1 1 1 FYVE zinc finger Ank_3 PF13606.6 OQS05604.1 - 6.5e-15 53.8 0.5 0.03 14.9 0.0 5.6 5 0 0 5 5 5 4 Ankyrin repeat Ank_4 PF13637.6 OQS05604.1 - 1.1e-14 54.6 1.2 2.3e-07 31.2 0.0 4.7 3 2 1 5 5 5 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 OQS05604.1 - 1.2e-12 47.8 4.5 0.011 16.1 0.2 4.7 3 1 1 4 4 4 4 Ankyrin repeats (many copies) FYVE_2 PF02318.16 OQS05604.1 - 0.0024 18.0 7.4 0.0053 17.0 7.4 1.6 1 0 0 1 1 1 1 FYVE-type zinc finger GF_recep_IV PF14843.6 OQS05604.1 - 0.52 10.1 9.4 0.092 12.6 5.2 1.8 2 0 0 2 2 2 0 Growth factor receptor domain IV Malic_M PF03949.15 OQS05605.1 - 9.7e-92 306.9 0.2 1.2e-91 306.5 0.2 1.1 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.19 OQS05605.1 - 1.8e-75 252.7 0.0 2.8e-75 252.1 0.0 1.3 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain EF-hand_1 PF00036.32 OQS05606.1 - 5.3e-26 88.2 19.4 8.1e-06 25.0 0.3 5.8 5 0 0 5 5 5 5 EF hand EF-hand_7 PF13499.6 OQS05606.1 - 4.1e-25 88.0 10.5 2.3e-10 40.8 1.3 4.5 3 1 0 4 4 4 3 EF-hand domain pair Pkinase_Tyr PF07714.17 OQS05606.1 - 1.1e-24 87.2 0.0 1.8e-24 86.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase EF-hand_6 PF13405.6 OQS05606.1 - 4.4e-24 82.3 21.0 1.2e-05 24.8 0.4 6.6 6 0 0 6 6 6 5 EF-hand domain EF-hand_5 PF13202.6 OQS05606.1 - 5.3e-20 70.0 19.9 0.00033 20.0 0.2 5.7 5 0 0 5 5 5 5 EF hand Pkinase PF00069.25 OQS05606.1 - 2.9e-18 66.2 0.0 6e-18 65.2 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain EF-hand_8 PF13833.6 OQS05606.1 - 1.8e-17 62.9 13.6 0.0055 16.5 0.1 6.2 6 0 0 6 6 6 5 EF-hand domain pair Caleosin PF05042.13 OQS05606.1 - 7.6e-06 26.0 1.7 0.088 12.7 0.2 3.7 2 1 1 3 3 3 2 Caleosin related protein EF-hand_4 PF12763.7 OQS05606.1 - 0.026 14.5 1.9 0.19 11.7 0.2 3.0 2 1 0 2 2 2 0 Cytoskeletal-regulatory complex EF hand SKG6 PF08693.10 OQS05606.1 - 0.04 13.3 3.0 0.087 12.2 3.0 1.6 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Syndecan PF01034.20 OQS05606.1 - 0.042 13.8 0.5 0.11 12.4 0.5 1.7 1 0 0 1 1 1 0 Syndecan domain SPARC_Ca_bdg PF10591.9 OQS05606.1 - 0.057 13.7 0.3 4.6 7.6 0.1 3.2 3 0 0 3 3 3 0 Secreted protein acidic and rich in cysteine Ca binding region UcrQ PF02939.16 OQS05606.1 - 0.11 12.4 0.0 0.29 11.1 0.0 1.6 1 0 0 1 1 1 0 UcrQ family Adeno_E3_CR2 PF02439.15 OQS05606.1 - 0.14 12.0 3.3 0.32 10.8 3.3 1.6 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 EF-hand_9 PF14658.6 OQS05606.1 - 0.35 11.2 1.4 22 5.5 0.0 3.8 4 0 0 4 4 3 0 EF-hand domain VSP PF03302.13 OQS05606.1 - 3.1 6.6 6.9 7.9 5.2 6.7 1.7 1 1 1 2 2 2 0 Giardia variant-specific surface protein ER_lumen_recept PF00810.18 OQS05607.1 - 2.8e-33 115.8 9.7 3.4e-33 115.5 7.2 2.0 2 0 0 2 2 2 1 ER lumen protein retaining receptor CAP59_mtransfer PF11735.8 OQS05608.1 - 9.1e-60 202.3 0.1 1.3e-59 201.8 0.1 1.2 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 Ank_2 PF12796.7 OQS05609.1 - 7.3e-24 84.2 4.7 5.5e-16 58.9 1.7 3.3 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQS05609.1 - 3.5e-20 72.1 1.7 3.2e-08 34.0 0.1 4.1 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 OQS05609.1 - 1.6e-18 66.3 3.5 0.00032 21.0 0.0 4.9 5 0 0 5 5 5 4 Ankyrin repeat Ank_5 PF13857.6 OQS05609.1 - 4.4e-17 61.9 3.3 2.6e-08 34.0 0.3 4.6 2 1 3 5 5 5 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQS05609.1 - 3.9e-16 57.5 1.7 0.00021 21.5 0.0 5.0 5 0 0 5 5 5 3 Ankyrin repeat Arg_repressor PF01316.21 OQS05609.1 - 0.072 12.9 0.0 24 4.8 0.0 3.1 3 0 0 3 3 3 0 Arginine repressor, DNA binding domain eIF_4EBP PF05456.11 OQS05610.1 - 0.0062 16.5 0.6 0.0062 16.5 0.6 2.1 2 0 0 2 2 2 1 Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) TPR_16 PF13432.6 OQS05610.1 - 0.11 13.2 0.1 0.21 12.3 0.1 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat C1_2 PF03107.16 OQS05610.1 - 6.8 7.1 14.4 4.3 7.7 0.6 2.9 3 0 0 3 3 3 0 C1 domain zf-TAZ PF02135.16 OQS05611.1 - 5.5e-24 84.4 41.2 1e-11 45.1 14.2 2.4 2 0 0 2 2 2 2 TAZ zinc finger Ank PF00023.30 OQS05612.1 - 4.3e-65 213.5 24.9 5.2e-09 36.1 0.1 13.7 12 1 1 13 13 13 10 Ankyrin repeat Ank_2 PF12796.7 OQS05612.1 - 1.4e-64 214.7 23.6 1e-15 58.1 2.7 9.3 3 3 5 8 8 8 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQS05612.1 - 2.7e-54 180.9 14.1 4.1e-10 40.0 0.1 11.4 4 1 7 11 11 11 9 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQS05612.1 - 3.4e-50 162.2 15.3 6.7e-07 29.1 0.0 13.2 13 1 1 14 14 14 9 Ankyrin repeat Ank_5 PF13857.6 OQS05612.1 - 5.9e-49 163.5 15.6 9.9e-09 35.3 0.0 10.2 8 2 4 12 12 12 8 Ankyrin repeats (many copies) Pkinase_Tyr PF07714.17 OQS05612.1 - 9.5e-31 107.0 3.5 1.9e-16 60.2 0.1 3.3 2 1 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 OQS05612.1 - 2.7e-20 72.9 4.0 1.4e-12 47.5 0.2 3.5 2 1 0 2 2 2 2 Protein kinase domain MetallophosN PF16371.5 OQS05612.1 - 0.019 15.2 0.0 0.98 9.7 0.0 3.2 3 0 0 3 3 3 0 N terminal of Calcineurin-like phosphoesterase Ribophorin_II PF05817.14 OQS05613.1 - 3.2e-58 197.8 4.4 5.4e-58 197.0 4.4 1.3 1 1 0 1 1 1 1 Oligosaccharyltransferase subunit Ribophorin II FF PF01846.19 OQS05614.1 - 5.7e-31 106.5 9.5 3.1e-10 40.1 0.0 5.5 5 0 0 5 5 5 4 FF domain WW PF00397.26 OQS05614.1 - 4.2e-08 33.1 1.9 1.3e-07 31.6 1.9 1.9 1 0 0 1 1 1 1 WW domain Mu-like_Pro PF10123.9 OQS05614.1 - 0.42 10.1 7.9 1.5 8.3 0.1 2.5 2 1 0 2 2 2 0 Mu-like prophage I protein Symplekin_C PF12295.8 OQS05615.1 - 7.1e-34 117.5 3.6 7.1e-34 117.5 3.6 3.8 4 1 0 4 4 4 1 Symplekin tight junction protein C terminal MFS_MOT1 PF16983.5 OQS05616.1 - 7.5e-52 174.4 28.7 2.8e-27 95.3 9.3 2.9 3 0 0 3 3 3 2 Molybdate transporter of MFS superfamily Sulfate_transp PF00916.20 OQS05616.1 - 4.5e-07 29.0 19.5 6.9e-07 28.4 19.5 1.3 1 0 0 1 1 1 1 Sulfate permease family DUF3453 PF11935.8 OQS05617.1 - 5.4e-05 22.9 0.1 0.00011 21.9 0.0 1.6 1 1 1 2 2 2 1 Domain of unknown function (DUF3453) RCC1 PF00415.18 OQS05619.1 - 1.3e-91 301.0 19.7 1.2e-17 64.3 0.5 7.1 7 0 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 OQS05619.1 - 5.5e-46 153.5 37.1 5.2e-12 45.2 0.6 8.2 8 0 0 8 8 8 8 Regulator of chromosome condensation (RCC1) repeat PH_6 PF15406.6 OQS05619.1 - 0.057 13.7 0.7 0.44 10.8 0.2 2.2 2 0 0 2 2 2 0 Pleckstrin homology domain DUF1921 PF09081.10 OQS05619.1 - 0.15 12.3 1.4 5.6 7.3 0.1 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF1921) Hira PF07569.11 OQS05619.1 - 0.16 11.6 0.0 11 5.7 0.0 3.4 5 0 0 5 5 5 0 TUP1-like enhancer of split Kelch_5 PF13854.6 OQS05619.1 - 0.55 10.3 4.1 17 5.5 0.0 4.2 5 0 0 5 5 5 0 Kelch motif Selenoprotein_S PF06936.11 OQS05620.1 - 2.4e-07 30.8 6.5 3.8e-06 26.8 1.1 2.1 1 1 1 2 2 2 2 Selenoprotein S (SelS) PIEZO PF15917.5 OQS05620.1 - 0.017 14.6 0.1 0.021 14.3 0.1 1.2 1 0 0 1 1 1 0 Piezo Zip PF02535.22 OQS05620.1 - 0.11 11.7 0.0 0.13 11.5 0.0 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Pkinase_Tyr PF07714.17 OQS05621.1 - 1.5e-13 50.6 0.1 7.8e-13 48.3 0.1 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase C2 PF00168.30 OQS05621.1 - 5.2e-12 46.0 0.0 9.2e-12 45.2 0.0 1.4 1 0 0 1 1 1 1 C2 domain Pkinase PF00069.25 OQS05621.1 - 5e-10 39.2 0.0 9.4e-10 38.3 0.0 1.3 1 1 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 OQS05621.1 - 8.9e-05 21.9 0.0 0.00014 21.3 0.0 1.2 1 0 0 1 1 1 1 Kinase-like 3-HAO PF06052.12 OQS05621.1 - 0.13 11.9 0.0 0.24 11.0 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyanthranilic acid dioxygenase SWI-SNF_Ssr4 PF08549.10 OQS05621.1 - 0.23 10.0 1.2 0.42 9.2 1.2 1.3 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) zf-C3HC4_3 PF13920.6 OQS05622.1 - 7.3e-05 22.6 8.3 7.3e-05 22.6 8.3 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 OQS05622.1 - 0.0036 17.6 11.1 0.0036 17.6 11.1 2.1 2 0 0 2 2 2 1 Ring finger domain zf-RanBP PF00641.18 OQS05622.1 - 0.018 14.3 5.3 0.018 14.3 5.3 2.7 3 0 0 3 3 3 0 Zn-finger in Ran binding protein and others zf-C3HC4_4 PF15227.6 OQS05622.1 - 0.028 14.6 10.9 0.028 14.6 10.9 2.7 2 1 0 2 2 2 0 zinc finger of C3HC4-type, RING DUF4100 PF13352.6 OQS05622.1 - 0.04 13.7 0.2 0.071 12.9 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4100) U-box PF04564.15 OQS05622.1 - 0.11 12.7 0.1 0.27 11.4 0.1 1.9 1 1 0 1 1 1 0 U-box domain PWI PF01480.17 OQS05623.1 - 1.1e-27 96.1 0.1 1.9e-27 95.4 0.1 1.4 1 0 0 1 1 1 1 PWI domain DUF936 PF06075.12 OQS05623.1 - 1.5 7.6 41.8 1.7 7.5 41.8 1.1 1 0 0 1 1 1 0 Plant protein of unknown function (DUF936) Abhydrolase_1 PF00561.20 OQS05624.1 - 1.4e-08 34.7 0.0 7.5e-08 32.3 0.0 1.8 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 OQS05624.1 - 0.0029 18.2 0.0 0.0067 17.1 0.0 1.6 1 1 1 2 2 2 1 Alpha/beta hydrolase family MAGE PF01454.19 OQS05625.1 - 6.5e-16 58.7 0.0 5e-15 55.8 0.0 2.1 1 1 0 1 1 1 1 MAGE family DTHCT PF08070.11 OQS05625.1 - 0.093 13.5 1.0 0.18 12.6 1.0 1.5 1 0 0 1 1 1 0 DTHCT (NUC029) region WD40 PF00400.32 OQS05627.1 - 1.6e-36 123.7 28.7 4.2e-09 36.9 0.6 8.2 8 0 0 8 8 8 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OQS05627.1 - 4.9e-16 58.8 2.7 0.01 16.1 0.1 5.5 1 1 4 5 5 5 5 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 OQS05627.1 - 5.4e-06 25.9 0.0 0.32 10.3 0.0 3.9 2 1 3 5 5 5 2 WD40-like domain eIF2A PF08662.11 OQS05627.1 - 5.6e-05 23.1 0.7 0.2 11.5 0.0 2.9 2 1 1 3 3 3 3 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 OQS05627.1 - 0.0025 16.6 0.3 17 3.9 0.1 4.0 3 1 1 4 4 4 1 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 OQS05627.1 - 0.0033 16.5 1.3 0.66 8.9 0.0 3.0 3 0 0 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein DUF5111 PF17138.4 OQS05627.1 - 0.14 12.0 1.7 7.6 6.4 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF5111) Abhydrolase_1 PF00561.20 OQS05628.1 - 2.1e-39 135.7 0.1 4.8e-25 88.7 0.0 3.4 2 2 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 OQS05628.1 - 2.1e-26 93.9 0.5 4.1e-17 63.5 0.0 2.2 2 0 0 2 2 2 2 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 OQS05628.1 - 1.6e-09 37.4 0.0 7.3e-05 22.1 0.0 3.1 3 0 0 3 3 3 3 Serine aminopeptidase, S33 EHN PF06441.12 OQS05628.1 - 4.2e-09 36.7 0.5 1.9e-06 28.2 0.1 2.8 2 0 0 2 2 2 2 Epoxide hydrolase N terminus Abhydrolase_4 PF08386.10 OQS05628.1 - 0.0019 18.3 0.0 0.98 9.6 0.0 2.3 2 0 0 2 2 2 2 TAP-like protein ESCRT-II PF05871.12 OQS05628.1 - 0.0073 16.6 0.2 2.1 8.6 0.1 2.3 2 0 0 2 2 2 2 ESCRT-II complex subunit Arrestin_C PF02752.22 OQS05629.1 - 1.7e-32 112.6 0.4 4.5e-13 49.8 0.0 4.4 4 0 0 4 4 4 2 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 OQS05629.1 - 3.6e-29 101.7 3.2 1.2e-12 48.1 0.1 4.2 4 0 0 4 4 4 3 Arrestin (or S-antigen), N-terminal domain Polyketide_cyc2 PF10604.9 OQS05629.1 - 0.00015 22.0 0.0 0.00043 20.6 0.0 1.8 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport LDB19 PF13002.7 OQS05629.1 - 0.00051 19.8 0.0 0.047 13.4 0.0 2.4 2 0 0 2 2 2 1 Arrestin_N terminal like CHORD PF04968.12 OQS05629.1 - 0.0039 17.9 4.5 0.01 16.5 4.5 1.7 1 0 0 1 1 1 1 CHORD Rgp1 PF08737.10 OQS05629.1 - 0.16 11.1 4.1 12 4.9 0.0 3.8 2 2 2 4 4 4 0 Rgp1 eIF-3_zeta PF05091.12 OQS05630.1 - 9e-187 622.2 0.4 1e-186 622.0 0.4 1.0 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) NARG2_C PF10505.9 OQS05630.1 - 0.028 14.0 0.0 0.36 10.3 0.0 2.2 2 0 0 2 2 2 0 NMDA receptor-regulated gene protein 2 C-terminus DUF4275 PF14101.6 OQS05631.1 - 0.13 12.4 0.1 0.25 11.5 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4275) SKG6 PF08693.10 OQS05631.1 - 2.5 7.6 3.8 5.1 6.6 3.8 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain UBA2_C PF16195.5 OQS05631.1 - 6.1 7.6 6.4 40 5.0 0.6 2.7 1 1 1 2 2 2 0 SUMO-activating enzyme subunit 2 C-terminus OrsD PF12013.8 OQS05632.1 - 0.01 16.3 2.1 0.023 15.1 2.1 1.6 1 0 0 1 1 1 0 Orsellinic acid/F9775 biosynthesis cluster protein D TMEM154 PF15102.6 OQS05632.1 - 0.019 14.9 1.1 0.019 14.9 1.1 2.3 2 0 0 2 2 2 0 TMEM154 protein family Glycophorin_A PF01102.18 OQS05632.1 - 0.05 13.8 3.1 0.13 12.5 3.1 1.9 1 1 0 1 1 1 0 Glycophorin A MFS_2 PF13347.6 OQS05632.1 - 0.15 10.6 0.0 0.21 10.1 0.0 1.1 1 0 0 1 1 1 0 MFS/sugar transport protein MGC-24 PF05283.11 OQS05632.1 - 0.46 10.9 10.0 1.2 9.6 10.0 1.7 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin TPR_12 PF13424.6 OQS05633.1 - 2.6e-09 37.3 0.1 1.9e-07 31.3 0.0 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.17 OQS05633.1 - 1.5e-07 31.0 0.0 0.00092 19.2 0.2 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 OQS05633.1 - 8.7e-07 28.5 0.1 0.00012 21.7 0.4 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_MalT PF17874.1 OQS05633.1 - 0.0012 18.2 0.2 0.0045 16.4 0.2 1.8 1 1 0 1 1 1 1 MalT-like TPR region TPR_8 PF13181.6 OQS05633.1 - 0.002 18.2 0.0 1.2 9.5 0.1 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 OQS05633.1 - 0.0026 18.4 0.0 20 6.3 0.0 4.3 2 1 3 5 5 4 0 Tetratricopeptide repeat TPR_16 PF13432.6 OQS05633.1 - 0.0058 17.3 0.2 1 10.1 0.0 3.3 1 1 2 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 OQS05633.1 - 0.0085 16.6 0.1 0.21 12.1 0.0 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat RPN7 PF10602.9 OQS05633.1 - 0.017 14.8 0.0 0.034 13.9 0.0 1.4 1 0 0 1 1 1 0 26S proteasome subunit RPN7 TPR_7 PF13176.6 OQS05633.1 - 0.023 14.7 0.1 13 6.1 0.1 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.6 OQS05633.1 - 0.026 15.1 0.0 0.23 12.2 0.1 2.6 3 0 0 3 3 1 0 Tetratricopeptide repeat PknG_TPR PF16918.5 OQS05633.1 - 0.11 11.2 0.3 0.29 9.8 0.0 1.7 2 0 0 2 2 2 0 Protein kinase G tetratricopeptide repeat Pkinase PF00069.25 OQS05634.1 - 3.4e-30 105.3 0.0 4.5e-30 104.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQS05634.1 - 1e-28 100.4 0.0 1.3e-28 100.1 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 OQS05634.1 - 0.017 14.5 0.0 0.025 13.9 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family LRR_8 PF13855.6 OQS05635.1 - 6.3e-12 45.1 13.5 0.00047 19.9 0.6 5.2 4 1 0 5 5 5 3 Leucine rich repeat LRR_4 PF12799.7 OQS05635.1 - 4e-09 36.6 16.3 0.001 19.5 0.4 4.9 5 0 0 5 5 5 2 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 OQS05635.1 - 0.0011 18.8 8.4 0.44 10.7 0.1 5.5 5 0 0 5 5 5 2 Leucine Rich repeat Notch PF00066.17 OQS05635.1 - 0.01 16.3 1.8 0.01 16.3 1.8 2.0 2 0 0 2 2 2 0 LNR domain FNIP PF05725.12 OQS05635.1 - 0.32 11.2 9.2 1 9.6 0.2 4.0 4 1 0 4 4 4 0 FNIP Repeat LRR_1 PF00560.33 OQS05635.1 - 0.65 10.8 12.2 12 6.9 0.1 6.1 5 2 0 5 5 5 0 Leucine Rich Repeat La PF05383.17 OQS05636.1 - 5e-18 64.9 0.5 1.8e-17 63.1 0.1 2.1 2 0 0 2 2 2 1 La domain RRM_3 PF08777.11 OQS05636.1 - 1.4e-14 54.0 0.1 4.4e-13 49.2 0.0 2.5 2 1 0 2 2 2 1 RNA binding motif RRM_1 PF00076.22 OQS05636.1 - 4.6e-14 52.0 0.1 9.7e-13 47.7 0.1 2.4 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PTS_2-RNA PF01885.16 OQS05636.1 - 0.048 13.7 0.0 0.29 11.2 0.0 2.2 2 1 0 2 2 2 0 RNA 2'-phosphotransferase, Tpt1 / KptA family AbiEi_3_N PF17194.4 OQS05636.1 - 0.066 13.2 0.1 3.4 7.7 0.1 2.3 2 0 0 2 2 2 0 Transcriptional regulator, AbiEi antitoxin N-terminal domain ATP-synt_Eps PF04627.13 OQS05636.1 - 0.1 12.6 4.0 3.8 7.6 0.2 3.7 5 0 0 5 5 5 0 Mitochondrial ATP synthase epsilon chain FYVE_2 PF02318.16 OQS05637.1 - 0.13 12.5 7.3 0.36 11.0 7.3 1.7 1 0 0 1 1 1 0 FYVE-type zinc finger FYVE PF01363.21 OQS05637.1 - 0.31 11.2 10.7 0.84 9.8 10.7 1.8 1 0 0 1 1 1 0 FYVE zinc finger Pkinase PF00069.25 OQS05638.1 - 1.3e-56 191.9 0.0 3.7e-36 124.9 0.0 2.1 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OQS05638.1 - 1.1e-28 100.3 0.0 5.7e-25 88.1 0.0 2.1 1 1 1 2 2 2 2 Protein tyrosine kinase Kdo PF06293.14 OQS05638.1 - 0.0003 20.2 0.1 0.00071 19.0 0.0 1.6 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 OQS05638.1 - 0.0088 15.4 0.0 0.8 9.0 0.0 2.4 2 0 0 2 2 2 2 Kinase-like APH PF01636.23 OQS05638.1 - 0.026 14.4 0.2 2.9 7.7 0.0 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.9 OQS05638.1 - 0.11 12.0 0.0 0.21 11.1 0.0 1.5 1 1 0 1 1 1 0 PhoP regulatory network protein YrbL Haspin_kinase PF12330.8 OQS05638.1 - 0.16 10.9 0.1 5.3 5.9 0.0 2.4 1 1 1 2 2 2 0 Haspin like kinase domain Nucleoporin_FG2 PF15967.5 OQS05639.1 - 1.3e-09 37.2 128.2 8.4e-09 34.5 35.8 4.2 1 1 1 3 3 3 2 Nucleoporin FG repeated region Ntox1 PF15500.6 OQS05639.1 - 0.065 13.6 0.1 0.23 11.8 0.1 1.9 1 0 0 1 1 1 0 Putative RNase-like toxin, toxin_1 Rubredoxin PF00301.20 OQS05639.1 - 0.16 12.0 0.0 0.41 10.7 0.0 1.7 1 0 0 1 1 1 0 Rubredoxin CdvA PF18822.1 OQS05639.1 - 0.17 11.7 3.7 3 7.7 0.9 2.6 3 0 0 3 3 3 0 CdvA-like coiled-coil domain Fez1 PF06818.15 OQS05639.1 - 0.34 11.3 13.4 0.49 10.8 12.1 1.8 1 1 1 2 2 2 0 Fez1 Taxilin PF09728.9 OQS05639.1 - 2.1 7.5 16.2 1.5 7.9 13.4 1.9 1 1 1 2 2 2 0 Myosin-like coiled-coil protein Caldesmon PF02029.15 OQS05639.1 - 3.6 6.2 10.9 8.8 5.0 11.0 1.4 1 1 0 1 1 1 0 Caldesmon Laminin_II PF06009.12 OQS05639.1 - 6.2 6.8 14.1 0.53 10.3 3.2 2.2 2 0 0 2 2 2 0 Laminin Domain II PhoLip_ATPase_C PF16212.5 OQS05640.1 - 2.2e-64 217.6 25.1 2.2e-64 217.6 25.1 2.6 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 OQS05640.1 - 4e-23 80.9 2.3 4e-23 80.9 2.3 2.5 2 0 0 2 2 2 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 OQS05640.1 - 1.1e-09 38.9 0.4 0.0018 18.6 0.0 3.4 2 1 0 3 3 3 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 OQS05640.1 - 1.9e-09 37.5 0.0 9.6e-09 35.2 0.0 2.1 2 0 0 2 2 2 1 Cation transport ATPase (P-type) E1-E2_ATPase PF00122.20 OQS05640.1 - 1.8e-06 27.6 0.0 1.8e-06 27.6 0.0 2.3 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase_3 PF08282.12 OQS05640.1 - 0.013 15.3 0.0 0.032 14.0 0.0 1.6 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase SKN1 PF03935.15 OQS05641.1 - 6.7e-35 120.4 12.2 5.8e-22 77.8 1.1 3.1 2 2 0 2 2 2 2 Beta-glucan synthesis-associated protein (SKN1) PH PF00169.29 OQS05641.1 - 0.015 15.8 0.0 0.047 14.2 0.0 1.8 1 0 0 1 1 1 0 PH domain DUF423 PF04241.15 OQS05642.1 - 3.8e-29 100.7 0.2 5.7e-29 100.2 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF423) Rossmann-like PF10727.9 OQS05642.1 - 0.11 12.4 0.0 0.12 12.2 0.0 1.2 1 0 0 1 1 1 0 Rossmann-like domain DUF2627 PF11118.8 OQS05642.1 - 1.2 9.8 4.1 4.5 7.9 3.9 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF2627) CLASP_N PF12348.8 OQS05643.1 - 8.4e-26 90.9 18.2 8.8e-23 81.1 3.5 3.7 3 3 0 4 4 4 2 CLASP N terminal HEAT_2 PF13646.6 OQS05643.1 - 0.0001 22.6 0.6 5 7.6 0.1 5.9 4 2 3 7 7 7 2 HEAT repeats HEAT PF02985.22 OQS05643.1 - 0.00055 20.0 1.6 3.6 8.1 0.0 5.0 5 0 0 5 5 5 1 HEAT repeat LuxT_C PF18285.1 OQS05643.1 - 3.5 8.2 6.3 6.2 7.4 0.0 4.1 5 0 0 5 5 5 0 Tetracycline repressor LuxT C-terminal domain DUP PF00674.18 OQS05646.1 - 0.82 9.8 3.2 53 4.0 0.0 3.9 4 0 0 4 4 4 0 DUP family PDZ_6 PF17820.1 OQS05647.1 - 1.3e-07 31.3 0.1 2.9e-07 30.2 0.1 1.6 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 OQS05647.1 - 0.00073 19.8 0.2 0.0019 18.5 0.0 1.7 2 0 0 2 2 2 1 PDZ domain PDZ_2 PF13180.6 OQS05647.1 - 0.0014 18.9 0.8 0.01 16.1 0.2 2.4 2 0 0 2 2 2 1 PDZ domain SNF2_N PF00176.23 OQS05648.1 - 4.1e-50 170.5 0.1 2e-49 168.2 0.1 2.1 2 1 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 OQS05648.1 - 1.3e-15 57.7 0.0 5.4e-15 55.7 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 OQS05648.1 - 7.5e-07 29.3 0.0 1.8e-06 28.1 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Macro PF01661.21 OQS05648.1 - 0.0022 18.0 0.0 0.005 16.9 0.0 1.7 1 0 0 1 1 1 1 Macro domain Pex14_N PF04695.13 OQS05648.1 - 0.17 12.5 1.4 0.32 11.6 1.4 1.4 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region MMR_HSR1 PF01926.23 OQS05649.1 - 7.7e-21 74.3 0.2 1.5e-20 73.4 0.2 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.16 OQS05649.1 - 1.2e-10 41.1 0.0 2.4e-10 40.1 0.0 1.5 1 0 0 1 1 1 1 AIG1 family GTP_EFTU PF00009.27 OQS05649.1 - 7.3e-10 38.7 0.0 2.1e-07 30.7 0.0 2.7 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 OQS05649.1 - 2.1e-09 37.7 1.6 0.00013 22.1 0.1 2.6 1 1 1 2 2 2 2 Dynamin family KH_2 PF07650.17 OQS05649.1 - 5.3e-08 32.6 0.0 1.2e-07 31.5 0.0 1.5 1 0 0 1 1 1 1 KH domain FeoB_N PF02421.18 OQS05649.1 - 1.5e-07 31.1 0.1 2.9e-07 30.2 0.1 1.5 1 0 0 1 1 1 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 OQS05649.1 - 0.00015 21.7 0.3 0.055 13.4 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase AAA_22 PF13401.6 OQS05649.1 - 0.014 15.6 0.1 0.072 13.4 0.1 2.1 1 1 0 1 1 1 0 AAA domain Phe_tRNA-synt_N PF02912.18 OQS05649.1 - 0.025 14.5 0.0 0.081 12.9 0.0 1.9 1 0 0 1 1 1 0 Aminoacyl tRNA synthetase class II, N-terminal domain Roc PF08477.13 OQS05649.1 - 0.041 14.1 0.0 0.12 12.5 0.0 1.8 1 1 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase GBP PF02263.19 OQS05649.1 - 0.11 11.7 0.0 0.22 10.7 0.0 1.4 1 0 0 1 1 1 0 Guanylate-binding protein, N-terminal domain KH_1 PF00013.29 OQS05649.1 - 0.12 12.2 0.1 0.33 10.8 0.1 1.7 1 0 0 1 1 1 0 KH domain EXS PF03124.14 OQS05650.1 - 3.4e-67 227.1 20.0 5.1e-67 226.5 20.0 1.3 1 0 0 1 1 1 1 EXS family SPX PF03105.19 OQS05650.1 - 7.4e-14 52.5 11.2 9.5e-07 29.1 0.2 3.1 1 1 2 3 3 3 3 SPX domain NUC130_3NT PF08158.12 OQS05650.1 - 0.0071 16.6 0.0 0.017 15.4 0.0 1.7 1 0 0 1 1 1 1 NUC130/3NT domain DIL PF01843.19 OQS05650.1 - 0.038 14.2 0.1 0.11 12.8 0.1 1.8 1 0 0 1 1 1 0 DIL domain CTP_transf_like PF01467.26 OQS05651.1 - 5.8e-10 39.5 0.0 7.7e-10 39.1 0.0 1.2 1 0 0 1 1 1 1 Cytidylyltransferase-like NUDIX PF00293.28 OQS05652.1 - 6.2e-08 32.8 0.5 1.8e-06 28.0 0.5 2.2 1 1 0 1 1 1 1 NUDIX domain IMPDH PF00478.25 OQS05653.1 - 2e-130 434.8 4.4 2.4e-130 434.5 4.4 1.1 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain CBS PF00571.28 OQS05653.1 - 4.2e-16 59.1 0.2 3.8e-08 33.7 0.1 3.5 3 0 0 3 3 3 2 CBS domain MTCP1 PF08991.10 OQS05653.1 - 1.1e-10 41.5 15.3 2.1e-10 40.7 15.3 1.5 1 0 0 1 1 1 1 Mature-T-Cell Proliferation I type NMO PF03060.15 OQS05653.1 - 1.5e-07 31.2 6.6 1e-06 28.4 2.3 2.5 3 0 0 3 3 3 1 Nitronate monooxygenase FMN_dh PF01070.18 OQS05653.1 - 5.2e-07 29.0 1.0 1.5e-06 27.5 0.8 1.8 2 0 0 2 2 2 1 FMN-dependent dehydrogenase His_biosynth PF00977.21 OQS05653.1 - 1.9e-05 24.2 1.9 0.00011 21.7 1.9 2.1 1 1 0 1 1 1 1 Histidine biosynthesis protein ThiG PF05690.14 OQS05653.1 - 0.001 18.5 0.2 0.0019 17.5 0.2 1.4 1 0 0 1 1 1 1 Thiazole biosynthesis protein ThiG DHO_dh PF01180.21 OQS05653.1 - 0.058 12.6 3.4 0.069 12.4 0.6 2.3 2 0 0 2 2 2 0 Dihydroorotate dehydrogenase DUF561 PF04481.12 OQS05653.1 - 0.074 12.2 2.8 0.26 10.4 0.9 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF561) G3P_antiterm PF04309.12 OQS05653.1 - 0.15 11.4 0.5 0.42 10.0 0.2 2.0 2 0 0 2 2 2 0 Glycerol-3-phosphate responsive antiterminator GDP_Man_Dehyd PF16363.5 OQS05654.1 - 1.8e-146 487.8 0.0 4.2e-146 486.6 0.0 1.6 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 OQS05654.1 - 2.8e-68 230.0 0.0 4.9e-68 229.2 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PH PF00169.29 OQS05654.1 - 4.9e-23 81.6 3.0 3.2e-12 46.9 0.1 3.0 3 0 0 3 3 3 2 PH domain Pribosyltran PF00156.27 OQS05654.1 - 1.4e-18 66.9 0.0 3.2e-18 65.8 0.0 1.5 1 0 0 1 1 1 1 Phosphoribosyl transferase domain VPS9 PF02204.18 OQS05654.1 - 5.5e-12 45.8 0.5 1.1e-11 44.8 0.5 1.5 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain RmlD_sub_bind PF04321.17 OQS05654.1 - 4e-06 26.2 0.0 8e-06 25.2 0.0 1.4 1 0 0 1 1 1 1 RmlD substrate binding domain PH_8 PF15409.6 OQS05654.1 - 7e-05 23.0 0.4 0.3 11.4 0.1 2.7 2 0 0 2 2 2 2 Pleckstrin homology domain PDZ_6 PF17820.1 OQS05654.1 - 0.00062 19.5 0.1 0.0018 18.1 0.1 1.8 1 0 0 1 1 1 1 PDZ domain PH_3 PF14593.6 OQS05654.1 - 0.00079 19.5 2.6 0.21 11.7 0.0 3.2 3 0 0 3 3 3 2 PH domain Polysacc_synt_2 PF02719.15 OQS05654.1 - 0.016 14.4 0.0 0.028 13.5 0.0 1.4 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein PDZ PF00595.24 OQS05654.1 - 0.029 14.7 0.0 0.07 13.5 0.0 1.7 1 0 0 1 1 1 0 PDZ domain PH_11 PF15413.6 OQS05654.1 - 0.13 12.6 3.0 4 7.9 0.6 3.4 2 2 0 2 2 2 0 Pleckstrin homology domain Pkinase PF00069.25 OQS05656.1 - 1.3e-19 70.6 0.0 1.4e-19 70.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQS05656.1 - 1.2e-18 67.3 0.0 1.3e-18 67.2 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 OQS05656.1 - 0.0012 18.2 0.0 0.0014 18.0 0.0 1.1 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OQS05656.1 - 0.0052 16.7 0.0 0.0061 16.5 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 OQS05656.1 - 0.012 15.0 0.0 0.012 15.0 0.0 1.0 1 0 0 1 1 1 0 Kinase-like Pkinase_fungal PF17667.1 OQS05656.1 - 0.031 13.1 0.0 0.035 12.9 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase Seadorna_VP7 PF07387.11 OQS05656.1 - 0.12 11.4 0.0 0.14 11.2 0.0 1.1 1 0 0 1 1 1 0 Seadornavirus VP7 Haspin_kinase PF12330.8 OQS05656.1 - 0.13 11.2 0.1 0.13 11.2 0.1 1.1 1 0 0 1 1 1 0 Haspin like kinase domain DUF2039 PF10217.9 OQS05657.1 - 5.3e-31 106.8 13.1 5.3e-31 106.8 13.1 1.5 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2039) Cript PF10235.9 OQS05657.1 - 0.0058 17.2 14.3 0.0058 17.2 14.3 2.0 2 1 0 2 2 2 1 Microtubule-associated protein CRIPT DUF3381 PF11861.8 OQS05657.1 - 0.046 13.5 8.7 0.07 12.9 8.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) FemAB_like PF04339.12 OQS05657.1 - 0.049 12.7 0.4 0.056 12.6 0.4 1.1 1 0 0 1 1 1 0 Peptidogalycan biosysnthesis/recognition DUF572 PF04502.13 OQS05657.1 - 0.31 10.6 11.2 0.4 10.2 6.7 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF572) zinc-ribbons_6 PF07191.12 OQS05657.1 - 0.38 10.8 14.9 0.75 9.8 14.9 1.5 1 1 0 1 1 1 0 zinc-ribbons ADK_lid PF05191.14 OQS05657.1 - 0.91 9.6 8.3 12 6.0 0.0 3.2 2 1 1 3 3 3 0 Adenylate kinase, active site lid Pkinase PF00069.25 OQS05658.1 - 5.1e-25 88.3 0.1 7.3e-24 84.5 0.1 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQS05658.1 - 6.2e-23 81.4 0.1 1.3e-19 70.5 0.0 2.1 1 1 1 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 OQS05658.1 - 0.01 14.6 0.0 0.011 14.6 0.0 1.0 1 0 0 1 1 1 0 Fungal protein kinase Kinase-like PF14531.6 OQS05658.1 - 0.12 11.7 0.0 0.13 11.5 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Kinesin PF00225.23 OQS05659.1 - 5.4e-97 324.7 0.8 1e-95 320.5 0.0 2.5 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 OQS05659.1 - 6.2e-29 100.9 0.4 3.4e-28 98.5 0.0 2.5 2 0 0 2 2 2 1 Microtubule binding APH PF01636.23 OQS05659.1 - 1.4e-13 51.4 0.0 3.6e-12 46.7 0.0 2.9 3 0 0 3 3 3 1 Phosphotransferase enzyme family Glyoxalase PF00903.25 OQS05659.1 - 1.5e-07 31.7 0.0 4.9e-07 30.0 0.0 1.9 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 OQS05659.1 - 0.051 13.8 0.0 0.14 12.5 0.0 1.7 1 0 0 1 1 1 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily HEPN_Apea PF18739.1 OQS05659.1 - 0.11 13.0 1.4 0.49 10.9 1.4 2.1 1 0 0 1 1 1 0 Apea-like HEPN Neocarzinostat PF00960.18 OQS05659.1 - 0.19 11.7 0.6 0.4 10.7 0.6 1.4 1 0 0 1 1 1 0 Neocarzinostatin family DEAD PF00270.29 OQS05659.1 - 1.4 8.7 4.2 16 5.2 0.0 3.6 4 0 0 4 4 4 0 DEAD/DEAH box helicase TAL_FSA PF00923.19 OQS05660.1 - 1.9e-100 335.9 0.3 2.5e-100 335.5 0.3 1.2 1 0 0 1 1 1 1 Transaldolase/Fructose-6-phosphate aldolase Pkinase PF00069.25 OQS05660.1 - 2e-50 171.6 0.0 3.3e-50 170.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQS05660.1 - 1.6e-49 168.5 0.0 2.4e-49 168.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase DUF3169 PF11368.8 OQS05660.1 - 0.55 9.7 5.2 0.17 11.4 2.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3169) RyR PF02026.16 OQS05661.1 - 6.9e-62 205.6 0.1 3.1e-30 104.2 0.0 2.9 2 0 0 2 2 2 2 RyR domain PKD_channel PF08016.12 OQS05661.1 - 1.4e-47 162.4 4.5 2.3e-47 161.6 4.5 1.3 1 0 0 1 1 1 1 Polycystin cation channel Ion_trans PF00520.31 OQS05661.1 - 2e-11 43.6 15.0 2e-11 43.6 15.0 1.7 2 0 0 2 2 2 1 Ion transport protein Ceramidase_alk PF04734.13 OQS05662.1 - 4.1e-142 474.4 0.0 2e-140 468.8 0.0 2.6 2 1 0 2 2 2 1 Neutral/alkaline non-lysosomal ceramidase, N-terminal Ceramidse_alk_C PF17048.5 OQS05662.1 - 2.6e-42 144.5 0.1 7.1e-42 143.1 0.1 1.8 1 0 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase, C-terminal HHH_5 PF14520.6 OQS05662.1 - 0.11 13.1 1.2 8.6 7.1 0.5 3.0 2 0 0 2 2 2 0 Helix-hairpin-helix domain HMG_box_5 PF14887.6 OQS05662.1 - 0.44 10.6 1.9 0.67 10.0 0.2 2.2 2 0 0 2 2 2 0 HMG (high mobility group) box 5 PLDc_2 PF13091.6 OQS05663.1 - 8.3e-14 51.6 0.3 2.1e-06 27.7 0.7 3.4 2 1 0 2 2 2 2 PLD-like domain PLDc PF00614.22 OQS05663.1 - 2e-12 46.7 0.8 2.9e-06 27.2 0.1 2.7 2 0 0 2 2 2 2 Phospholipase D Active site motif Mito_carr PF00153.27 OQS05663.1 - 5.6e-06 26.2 6.3 1.4 8.9 0.0 5.2 3 2 2 5 5 5 2 Mitochondrial carrier protein PX PF00787.24 OQS05663.1 - 0.05 13.6 0.1 0.8 9.7 0.0 2.5 2 0 0 2 2 2 0 PX domain DUF3671 PF12420.8 OQS05663.1 - 1.8 8.7 5.5 6.2 6.9 5.5 1.9 1 0 0 1 1 1 0 Protein of unknown function Methyltransf_16 PF10294.9 OQS05664.1 - 2.1e-23 83.0 0.0 3.8e-23 82.1 0.0 1.4 1 1 0 1 1 1 1 Lysine methyltransferase MTS PF05175.14 OQS05664.1 - 3e-05 23.6 0.0 4.9e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_23 PF13489.6 OQS05664.1 - 0.00048 20.0 0.0 0.00061 19.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Mst1_SARAH PF11629.8 OQS05664.1 - 0.057 13.5 0.3 1.4 9.0 0.0 2.7 2 0 0 2 2 2 0 C terminal SARAH domain of Mst1 Methyltransf_25 PF13649.6 OQS05664.1 - 0.091 13.5 0.0 0.19 12.5 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain DUF938 PF06080.12 OQS05664.1 - 0.16 11.8 0.0 0.24 11.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF938) PCMT PF01135.19 OQS05664.1 - 0.17 11.6 0.0 0.3 10.8 0.0 1.3 1 1 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) YjgF_endoribonc PF14588.6 OQS05665.1 - 7.6e-30 104.0 0.1 8.4e-30 103.9 0.1 1.0 1 0 0 1 1 1 1 YjgF/chorismate_mutase-like, putative endoribonuclease Ribonuc_L-PSP PF01042.21 OQS05665.1 - 5.2e-17 62.0 0.1 1.1e-16 60.9 0.1 1.5 1 1 0 1 1 1 1 Endoribonuclease L-PSP LTD PF00932.19 OQS05666.1 - 1.5e-10 41.4 0.0 2.3e-10 40.8 0.0 1.3 1 0 0 1 1 1 1 Lamin Tail Domain AIM24 PF01987.17 OQS05667.1 - 1.7e-61 207.5 1.7 2.3e-61 207.1 1.7 1.2 1 0 0 1 1 1 1 Mitochondrial biogenesis AIM24 WW PF00397.26 OQS05667.1 - 0.00036 20.5 0.1 0.0008 19.4 0.1 1.6 1 0 0 1 1 1 1 WW domain UQ_con PF00179.26 OQS05668.1 - 4.7e-15 55.5 0.0 5.6e-15 55.2 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UEV PF05743.13 OQS05668.1 - 0.0085 15.9 0.0 0.011 15.6 0.0 1.2 1 0 0 1 1 1 1 UEV domain RWD PF05773.22 OQS05668.1 - 0.057 13.7 0.0 0.058 13.7 0.0 1.2 1 0 0 1 1 1 0 RWD domain PX PF00787.24 OQS05669.1 - 0.00021 21.3 0.0 0.00034 20.6 0.0 1.4 1 0 0 1 1 1 1 PX domain DUF2024 PF09630.10 OQS05669.1 - 0.019 14.9 0.1 0.054 13.4 0.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF2024) Lebercilin PF15619.6 OQS05670.1 - 5.1e-09 36.1 35.0 5.1e-09 36.1 35.0 3.1 2 1 1 3 3 3 1 Ciliary protein causing Leber congenital amaurosis disease Csm1_N PF18504.1 OQS05670.1 - 0.0022 18.3 5.3 0.0022 18.3 5.3 6.0 3 1 5 8 8 8 1 Csm1 N-terminal domain Tup_N PF08581.10 OQS05670.1 - 0.0073 16.6 2.2 0.0073 16.6 2.2 5.2 1 1 4 5 5 5 2 Tup N-terminal DUF1593 PF07632.11 OQS05670.1 - 0.044 13.2 3.3 0.15 11.5 3.2 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF1593) Ephrin_lbd PF01404.19 OQS05670.1 - 0.21 11.6 3.9 0.18 11.8 1.6 2.0 1 1 0 1 1 1 0 Ephrin receptor ligand binding domain GP3_package PF16677.5 OQS05670.1 - 4.5 7.4 8.1 1.7 8.8 3.6 2.4 2 1 0 2 2 2 0 DNA-packaging protein gp3 Ank_2 PF12796.7 OQS05671.1 - 7.4e-47 157.9 21.0 2.7e-12 47.1 0.1 7.8 5 2 3 9 9 9 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQS05671.1 - 1.4e-34 118.0 11.7 1.6e-05 25.4 0.0 8.1 2 1 8 10 10 10 9 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQS05671.1 - 1.6e-29 98.7 14.1 0.0004 20.6 0.0 11.9 11 0 0 11 11 11 7 Ankyrin repeat Ank PF00023.30 OQS05671.1 - 2.7e-28 97.1 24.0 1.2e-06 28.7 0.0 11.3 9 1 0 9 9 9 5 Ankyrin repeat Ank_5 PF13857.6 OQS05671.1 - 5.8e-27 93.4 18.1 1.4e-05 25.3 0.1 7.3 3 2 4 7 7 7 7 Ankyrin repeats (many copies) RIH_assoc PF08454.11 OQS05671.1 - 1.8e-12 47.0 0.1 9.3e-12 44.7 0.1 2.3 1 0 0 1 1 1 1 RyR and IP3R Homology associated Ion_trans PF00520.31 OQS05671.1 - 5.2e-06 25.9 31.4 5.2e-06 25.9 31.4 2.1 2 0 0 2 2 2 1 Ion transport protein Ins145_P3_rec PF08709.11 OQS05671.1 - 9.6e-05 21.7 0.0 0.00026 20.3 0.0 1.7 1 0 0 1 1 1 1 Inositol 1,4,5-trisphosphate/ryanodine receptor Lipase_GDSL PF00657.22 OQS05672.1 - 0.039 13.9 4.2 1.3 8.9 4.2 2.3 1 1 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase YjfB_motility PF14070.6 OQS05672.1 - 0.13 12.4 12.1 0.33 11.1 2.8 2.6 1 1 1 2 2 2 0 Putative motility protein Imm44 PF15571.6 OQS05672.1 - 0.37 11.1 6.0 0.27 11.5 3.5 2.1 1 1 0 2 2 2 0 Immunity protein 44 Csm1_N PF18504.1 OQS05672.1 - 0.49 10.8 40.5 0.53 10.7 3.2 5.7 3 2 2 5 5 5 0 Csm1 N-terminal domain DUF4795 PF16043.5 OQS05672.1 - 0.65 9.6 34.9 0.069 12.7 24.8 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4795) DUF4407 PF14362.6 OQS05672.1 - 0.97 8.7 24.4 0.054 12.8 12.8 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) T2SSF PF00482.23 OQS05672.1 - 2.4 8.2 4.6 1 9.3 1.1 2.0 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein F Golgin_A5 PF09787.9 OQS05672.1 - 2.6 7.5 38.7 6.6 6.1 20.8 2.4 1 1 1 2 2 2 0 Golgin subfamily A member 5 Peptidase_S66C PF17676.1 OQS05672.1 - 5.9 7.4 7.5 9.4 6.8 0.2 3.3 2 1 1 3 3 3 0 LD-carboxypeptidase C-terminal domain THOC7 PF05615.13 OQS05672.1 - 8.7 6.6 32.7 1.7e+04 -4.0 32.7 3.3 1 1 0 1 1 1 0 Tho complex subunit 7 TPR_1 PF00515.28 OQS05673.1 - 2.5e-13 49.2 0.0 0.0014 18.3 0.0 3.8 3 0 0 3 3 3 3 Tetratricopeptide repeat HSA PF07529.13 OQS05673.1 - 4e-10 39.9 3.5 1.5e-09 38.0 3.5 2.0 1 1 0 1 1 1 1 HSA TPR_2 PF07719.17 OQS05673.1 - 3.2e-09 36.2 0.0 0.0012 18.8 0.0 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat Myb_DNA-bind_6 PF13921.6 OQS05673.1 - 6.9e-09 35.8 0.3 2.1e-08 34.3 0.3 1.9 1 0 0 1 1 1 1 Myb-like DNA-binding domain TPR_9 PF13371.6 OQS05673.1 - 2.5e-08 33.9 0.1 0.00057 20.0 0.0 2.7 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.6 OQS05673.1 - 5.5e-08 33.3 0.0 1.1e-06 29.1 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat Myb_DNA-binding PF00249.31 OQS05673.1 - 1.3e-06 28.5 0.6 3.8e-06 27.0 0.6 1.9 1 0 0 1 1 1 1 Myb-like DNA-binding domain SNF2_N PF00176.23 OQS05673.1 - 2.5e-06 26.5 0.0 5.2e-06 25.4 0.0 1.6 1 1 0 1 1 1 1 SNF2 family N-terminal domain TPR_11 PF13414.6 OQS05673.1 - 0.002 17.8 0.0 0.19 11.4 0.0 3.1 1 1 2 3 3 3 1 TPR repeat TPR_19 PF14559.6 OQS05673.1 - 0.0026 18.2 0.0 0.014 15.9 0.0 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 OQS05673.1 - 0.0041 17.2 0.0 1.6 9.1 0.0 3.9 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 OQS05673.1 - 0.0082 16.4 0.4 1.2 9.4 0.0 2.7 1 1 0 2 2 2 1 Tetratricopeptide repeat zf-C2H2_12 PF18658.1 OQS05673.1 - 0.024 14.2 0.3 0.061 12.9 0.0 1.8 2 0 0 2 2 2 0 Zinc-finger C2H2-type TPR_14 PF13428.6 OQS05673.1 - 0.05 14.4 2.1 2.6 9.1 0.0 3.8 2 1 2 4 4 3 0 Tetratricopeptide repeat TPR_17 PF13431.6 OQS05673.1 - 0.07 13.5 0.0 1.4 9.5 0.0 3.0 3 0 0 3 3 2 0 Tetratricopeptide repeat Dynactin_p22 PF07426.11 OQS05674.1 - 0.003 17.4 2.8 0.009 15.9 2.8 1.9 1 1 0 1 1 1 1 Dynactin subunit p22 OmpH PF03938.14 OQS05674.1 - 0.0047 17.3 1.1 3.3 8.0 0.1 2.5 2 0 0 2 2 2 2 Outer membrane protein (OmpH-like) QWRF PF04484.12 OQS05674.1 - 0.014 15.1 5.5 0.017 14.9 4.9 1.3 1 1 0 1 1 1 0 QWRF family SlyX PF04102.12 OQS05674.1 - 0.032 14.9 5.4 2.8 8.6 0.1 3.8 2 1 1 3 3 3 0 SlyX DUF1664 PF07889.12 OQS05674.1 - 0.032 14.3 1.3 1.4 9.0 0.1 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) Laminin_II PF06009.12 OQS05674.1 - 0.044 13.8 0.1 0.044 13.8 0.1 2.5 3 0 0 3 3 3 0 Laminin Domain II FlxA PF14282.6 OQS05674.1 - 0.048 13.7 0.8 0.048 13.7 0.8 3.4 3 1 0 3 3 3 0 FlxA-like protein Exonuc_VII_L PF02601.15 OQS05674.1 - 0.13 11.8 11.3 0.39 10.2 10.3 1.8 1 1 0 1 1 1 0 Exonuclease VII, large subunit BST2 PF16716.5 OQS05674.1 - 0.17 12.5 0.2 0.17 12.5 0.2 3.1 3 2 1 4 4 4 0 Bone marrow stromal antigen 2 DASH_Dam1 PF08653.10 OQS05674.1 - 0.2 11.5 3.5 16 5.4 0.2 3.4 3 0 0 3 3 3 0 DASH complex subunit Dam1 CorA PF01544.18 OQS05674.1 - 0.21 10.9 5.2 0.096 12.0 1.7 1.9 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein Spc24 PF08286.11 OQS05674.1 - 7.9 6.8 9.2 0.86 9.9 0.5 3.0 2 1 1 3 3 3 0 Spc24 subunit of Ndc80 EF-hand_6 PF13405.6 OQS05675.1 - 4.1e-10 38.7 0.3 0.0002 21.0 0.0 2.7 3 0 0 3 3 3 2 EF-hand domain EF-hand_7 PF13499.6 OQS05675.1 - 1.3e-09 38.4 1.4 0.00044 20.7 0.1 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 OQS05675.1 - 6.9e-08 31.5 0.2 0.0098 15.4 0.0 2.6 2 0 0 2 2 2 2 EF hand EF-hand_9 PF14658.6 OQS05675.1 - 0.00055 20.2 0.5 1 9.7 0.0 2.8 3 0 0 3 3 3 2 EF-hand domain EFhand_Ca_insen PF08726.10 OQS05675.1 - 0.015 15.4 2.8 0.046 13.8 0.3 2.5 2 1 0 2 2 2 0 Ca2+ insensitive EF hand DUF2666 PF10869.8 OQS05675.1 - 0.025 14.8 0.4 0.97 9.6 0.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2666) EF-hand_8 PF13833.6 OQS05675.1 - 0.035 14.0 0.1 7.5 6.5 0.0 2.7 2 0 0 2 2 2 0 EF-hand domain pair PcfK PF14058.6 OQS05676.1 - 0.019 15.3 5.8 0.019 15.3 5.8 1.9 2 0 0 2 2 2 0 PcfK-like protein Peptidase_S49_N PF08496.10 OQS05676.1 - 3.1 7.8 9.4 0.33 11.0 3.6 2.3 3 0 0 3 3 3 0 Peptidase family S49 N-terminal HECT PF00632.25 OQS05677.1 - 2.9e-156 519.7 0.1 3e-77 260.1 0.0 2.4 2 0 0 2 2 2 2 HECT-domain (ubiquitin-transferase) Aldo_ket_red PF00248.21 OQS05677.1 - 2.2e-40 138.7 0.0 3.7e-40 138.0 0.0 1.3 1 0 0 1 1 1 1 Aldo/keto reductase family zf-RanBP PF00641.18 OQS05677.1 - 1.4e-10 40.3 10.4 3.7e-05 22.9 2.3 2.4 2 0 0 2 2 2 2 Zn-finger in Ran binding protein and others SUKH_5 PF14567.6 OQS05677.1 - 4.8e-05 23.1 0.1 0.24 11.1 0.0 2.6 2 0 0 2 2 2 2 SMI1-KNR4 cell-wall Vps36-NZF-N PF16988.5 OQS05677.1 - 0.0056 16.0 8.2 0.5 9.8 0.9 3.1 2 1 0 2 2 2 2 Vacuolar protein sorting 36 NZF-N zinc-finger domain GCV_H PF01597.19 OQS05677.1 - 0.021 14.7 0.5 0.43 10.5 0.1 2.4 2 0 0 2 2 2 0 Glycine cleavage H-protein BACK PF07707.15 OQS05678.1 - 0.065 13.3 0.5 1.4 9.0 0.0 2.6 1 1 1 2 2 2 0 BTB And C-terminal Kelch Mur_ligase_M PF08245.12 OQS05679.1 - 6.7e-10 39.3 0.0 1.2e-09 38.5 0.0 1.4 1 0 0 1 1 1 1 Mur ligase middle domain Mur_ligase_C PF02875.21 OQS05679.1 - 3.7e-07 30.3 0.0 1.2e-06 28.7 0.0 1.9 1 0 0 1 1 1 1 Mur ligase family, glutamate ligase domain zinc_ribbon_16 PF17034.5 OQS05681.1 - 2.2e-21 76.4 8.2 6.4e-21 74.8 8.2 1.8 1 1 0 1 1 1 1 Zinc-ribbon like family WD40 PF00400.32 OQS05681.1 - 4.8e-05 24.0 9.4 0.016 16.1 0.1 5.7 6 0 0 6 6 6 1 WD domain, G-beta repeat Zn_ribbon_17 PF17120.5 OQS05681.1 - 0.017 14.7 11.1 0.074 12.7 11.1 2.1 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-ribbon_3 PF13248.6 OQS05681.1 - 0.078 12.4 1.9 12 5.5 0.5 2.9 2 0 0 2 2 2 0 zinc-ribbon domain KH_1 PF00013.29 OQS05682.1 - 2.3e-81 267.6 13.0 7e-12 45.0 0.1 11.2 11 0 0 11 11 11 8 KH domain KH_2 PF07650.17 OQS05682.1 - 4.7e-18 64.8 4.5 0.035 13.9 0.4 8.2 7 0 0 7 7 7 6 KH domain KH_4 PF13083.6 OQS05682.1 - 5.6e-15 55.0 17.4 0.018 14.9 0.0 9.7 9 2 2 11 11 11 5 KH domain SLS PF14611.6 OQS05682.1 - 7.7e-09 35.7 27.6 5.1e-05 23.2 0.3 7.4 5 2 3 9 9 9 3 Mitochondrial inner-membrane-bound regulator KH_5 PF13184.6 OQS05682.1 - 1.7e-06 28.0 8.3 0.83 9.8 0.1 6.6 6 0 0 6 6 6 2 NusA-like KH domain MOEP19 PF16005.5 OQS05682.1 - 0.0004 20.3 0.1 30 4.7 0.0 6.0 7 0 0 7 7 7 0 KH-like RNA-binding domain PilN PF05137.13 OQS05682.1 - 0.046 13.9 1.4 11 6.3 0.0 4.7 5 0 0 5 5 5 0 Fimbrial assembly protein (PilN) DUF364 PF04016.12 OQS05682.1 - 0.077 12.6 0.1 1.8 8.1 0.0 2.8 2 0 0 2 2 2 0 Putative heavy-metal chelation ExbD PF02472.16 OQS05682.1 - 5.7 7.1 12.1 13 6.0 0.0 5.9 6 2 1 7 7 7 0 Biopolymer transport protein ExbD/TolR DUF3181 PF11378.8 OQS05683.1 - 0.068 13.5 0.7 0.95 9.8 0.1 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3181) ALG3 PF05208.13 OQS05684.1 - 1.2e-41 143.3 11.8 2.1e-41 142.6 11.8 1.3 1 0 0 1 1 1 1 ALG3 protein DUF2470 PF10615.9 OQS05684.1 - 0.0023 18.5 0.0 0.0047 17.5 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2470) DUF1348 PF07080.11 OQS05686.1 - 4.6e-58 194.8 0.9 7.5e-58 194.1 0.9 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1348) SnoaL_2 PF12680.7 OQS05686.1 - 5.6e-10 39.8 0.4 5.6e-10 39.8 0.4 1.9 2 0 0 2 2 2 1 SnoaL-like domain DUF4440 PF14534.6 OQS05686.1 - 0.00024 21.5 0.1 0.00049 20.5 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) LEA_2 PF03168.13 OQS05686.1 - 0.024 15.1 0.0 0.049 14.2 0.0 1.4 1 0 0 1 1 1 0 Late embryogenesis abundant protein SnoaL PF07366.12 OQS05686.1 - 0.055 13.3 0.1 0.12 12.2 0.1 1.5 1 0 0 1 1 1 0 SnoaL-like polyketide cyclase DUF5029 PF16432.5 OQS05686.1 - 0.15 11.6 0.0 0.23 11.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5029) PSI PF01437.25 OQS05686.1 - 1 9.9 10.3 3.6 8.2 10.3 2.0 1 0 0 1 1 1 0 Plexin repeat PSI_integrin PF17205.3 OQS05686.1 - 5.8 6.7 14.2 0.25 11.1 7.9 2.0 2 0 0 2 2 2 0 Integrin plexin domain Diphthamide_syn PF01866.17 OQS05688.1 - 3.5e-88 296.0 0.3 4.9e-88 295.5 0.3 1.2 1 0 0 1 1 1 1 Putative diphthamide synthesis protein Trypsin_2 PF13365.6 OQS05688.1 - 1.9e-12 48.4 0.0 3.4e-12 47.5 0.0 1.4 1 0 0 1 1 1 1 Trypsin-like peptidase domain Orn_Arg_deC_N PF02784.16 OQS05689.1 - 7.7e-76 254.7 0.0 1e-75 254.3 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.22 OQS05689.1 - 1e-17 64.2 0.0 1.7e-17 63.5 0.0 1.4 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain PAN_4 PF14295.6 OQS05690.1 - 1.6e-86 284.1 141.6 4e-09 36.2 2.8 13.0 12 1 0 12 12 12 12 PAN domain PAN_1 PF00024.26 OQS05690.1 - 6.3e-56 186.3 84.8 4.7e-06 26.5 1.9 12.4 5 4 7 12 12 12 12 PAN domain GMC_oxred_N PF00732.19 OQS05690.1 - 5.5e-31 108.0 0.2 3.2e-26 92.4 0.0 2.7 2 0 0 2 2 2 2 GMC oxidoreductase GMC_oxred_C PF05199.13 OQS05690.1 - 7.2e-10 39.6 0.1 1.7e-09 38.4 0.1 1.6 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.6 OQS05690.1 - 6.2e-06 26.4 1.3 2.3e-05 24.5 0.2 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 OQS05690.1 - 1.7e-05 24.1 0.7 0.00043 19.5 1.1 2.1 2 0 0 2 2 2 1 FAD binding domain Consortin_C PF15281.6 OQS05690.1 - 7.2e-05 22.7 2.3 8.4 6.4 0.0 4.8 4 0 0 4 4 4 1 Consortin C-terminus Pyr_redox_2 PF07992.14 OQS05690.1 - 8.1e-05 22.0 0.0 0.00017 20.9 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 OQS05690.1 - 0.00014 21.2 2.1 0.00022 20.5 1.0 1.8 2 0 0 2 2 2 1 Thi4 family FAD_binding_3 PF01494.19 OQS05690.1 - 0.00093 18.5 1.1 0.0015 17.9 1.1 1.2 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 OQS05690.1 - 0.0075 15.0 0.9 0.033 12.9 0.7 1.9 2 0 0 2 2 2 1 HI0933-like protein FAD_oxidored PF12831.7 OQS05690.1 - 0.025 13.9 0.2 0.045 13.1 0.2 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase DAO PF01266.24 OQS05690.1 - 0.033 13.8 2.4 0.065 12.8 2.4 1.5 1 0 0 1 1 1 0 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 OQS05690.1 - 0.073 12.1 0.8 0.11 11.5 0.8 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein PAN_4 PF14295.6 OQS05691.1 - 6.3e-13 48.4 20.4 1.1e-08 34.8 3.5 2.7 2 1 0 2 2 2 2 PAN domain PAN_1 PF00024.26 OQS05691.1 - 7.6e-11 41.8 9.9 2.3e-05 24.2 2.7 2.1 1 1 1 2 2 2 2 PAN domain PAN_2 PF08276.11 OQS05691.1 - 0.005 16.9 3.5 0.005 16.9 3.5 2.2 2 0 0 2 2 2 1 PAN-like domain PIF3 PF05006.12 OQS05691.1 - 0.026 14.6 9.0 0.5 10.4 1.1 2.1 2 0 0 2 2 2 0 Per os infectivity factor 3 MANEC PF07502.14 OQS05691.1 - 0.036 14.3 8.3 0.78 10.0 0.9 2.4 2 0 0 2 2 2 0 MANEC domain PAN_3 PF08277.12 OQS05691.1 - 0.11 12.3 14.8 0.23 11.3 2.1 2.3 2 0 0 2 2 2 0 PAN-like domain DUF4211 PF13926.6 OQS05691.1 - 1.5 8.9 4.8 3.4 7.7 0.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4211) ABM PF03992.16 OQS05692.1 - 4.7e-13 49.1 0.1 5.3e-13 48.9 0.1 1.1 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase Dehydratase_hem PF13816.6 OQS05692.1 - 8.9e-05 22.0 0.1 9.6e-05 21.9 0.1 1.0 1 0 0 1 1 1 1 Haem-containing dehydratase Dabb PF07876.12 OQS05692.1 - 0.008 16.8 0.0 0.01 16.5 0.0 1.1 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain DUF1330 PF07045.11 OQS05692.1 - 0.046 14.1 0.0 0.054 13.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1330) Ank_5 PF13857.6 OQS05693.1 - 2.4e-23 81.9 8.9 0.0018 18.5 0.1 8.3 2 1 6 8 8 8 6 Ankyrin repeats (many copies) Ank_2 PF12796.7 OQS05693.1 - 1.4e-21 76.9 6.3 2e-06 28.3 0.1 4.1 1 1 3 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQS05693.1 - 1.1e-20 73.7 9.7 8e-07 29.5 0.1 5.4 4 1 1 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQS05693.1 - 1.3e-14 52.8 2.7 0.56 10.9 0.0 7.5 5 1 2 7 7 7 4 Ankyrin repeat DUF3447 PF11929.8 OQS05693.1 - 0.00039 20.3 1.0 0.054 13.4 0.0 3.4 2 1 1 3 3 3 1 Domain of unknown function (DUF3447) DUF5049 PF16468.5 OQS05693.1 - 0.0027 17.6 1.0 14 5.6 0.0 5.0 4 2 2 6 6 6 1 Domain of unknown function (DUF5049) VHL_C PF17211.3 OQS05693.1 - 0.0034 17.4 0.1 2.3 8.3 0.0 3.8 4 0 0 4 4 4 1 VHL box domain Ank PF00023.30 OQS05693.1 - 0.0079 16.6 0.5 40 4.9 0.0 5.6 5 3 0 5 5 5 0 Ankyrin repeat DUF1843 PF08898.10 OQS05693.1 - 0.0097 16.4 0.0 2.9 8.5 0.0 3.9 5 0 0 5 5 5 1 Domain of unknown function (DUF1843) DUF3310 PF11753.8 OQS05693.1 - 0.18 12.0 1.3 1.1 9.5 0.1 2.9 3 0 0 3 3 3 0 Protein of unknwon function (DUF3310) Peptidase_M14 PF00246.24 OQS05694.1 - 2.7e-20 73.4 0.4 1e-19 71.4 0.4 2.0 1 1 0 1 1 1 1 Zinc carboxypeptidase TMEM154 PF15102.6 OQS05694.1 - 0.0064 16.4 0.2 0.015 15.2 0.2 1.6 1 0 0 1 1 1 1 TMEM154 protein family CSG2 PF16965.5 OQS05694.1 - 0.11 11.4 0.2 0.17 10.8 0.2 1.2 1 0 0 1 1 1 0 Ceramide synthase regulator GIDE PF12483.8 OQS05695.1 - 1.3e-06 27.9 0.0 3.4e-06 26.6 0.0 1.9 1 1 0 1 1 1 1 E3 Ubiquitin ligase Ank_3 PF13606.6 OQS05696.1 - 0.0048 17.3 0.0 0.03 14.8 0.0 2.0 2 0 0 2 2 2 1 Ankyrin repeat Ank_4 PF13637.6 OQS05696.1 - 0.075 13.6 0.0 0.082 13.5 0.0 1.3 1 1 0 1 1 1 0 Ankyrin repeats (many copies) EF-hand_7 PF13499.6 OQS05697.1 - 0.00068 20.0 3.7 0.034 14.6 3.7 2.7 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.6 OQS05697.1 - 0.0058 16.1 0.0 0.017 14.6 0.0 1.8 1 0 0 1 1 1 1 EF hand EF-hand_1 PF00036.32 OQS05697.1 - 0.029 13.9 0.0 0.13 11.9 0.0 2.2 1 0 0 1 1 1 0 EF hand EF-hand_6 PF13405.6 OQS05697.1 - 0.051 13.5 0.6 0.54 10.3 0.0 3.1 3 0 0 3 3 3 0 EF-hand domain DnaJ_C PF01556.18 OQS05698.1 - 9.2e-38 129.6 0.0 1.2e-37 129.3 0.0 1.1 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 OQS05698.1 - 3.1e-24 84.9 2.1 4.9e-24 84.2 2.1 1.3 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 OQS05698.1 - 9.5e-13 48.3 14.1 2.1e-12 47.2 14.1 1.6 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 OQS05698.1 - 0.0043 17.0 16.5 0.031 14.2 5.9 2.9 1 1 1 2 2 2 2 Tryptophan RNA-binding attenuator protein inhibitory protein HypA PF01155.19 OQS05698.1 - 0.72 9.9 8.5 0.23 11.5 1.1 2.4 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Microvir_J PF04726.13 OQS05698.1 - 1.7 8.7 5.7 0.78 9.8 1.9 2.2 2 0 0 2 2 2 0 Microvirus J protein PH_2 PF08458.10 OQS05699.1 - 0.0017 18.6 0.5 0.0025 18.1 0.5 1.2 1 0 0 1 1 1 1 Plant pleckstrin homology-like region PH PF00169.29 OQS05699.1 - 0.052 14.1 0.1 0.073 13.6 0.1 1.3 1 0 0 1 1 1 0 PH domain Peptidase_C69 PF03577.15 OQS05700.1 - 3.4e-39 134.9 1.5 2.3e-38 132.2 1.5 2.2 1 1 0 1 1 1 1 Peptidase family C69 Phage_attach PF05354.11 OQS05700.1 - 0.056 13.3 0.0 0.38 10.7 0.0 2.1 2 0 0 2 2 2 0 Phage Head-Tail Attachment Ank_5 PF13857.6 OQS05702.1 - 3.2e-13 49.6 0.6 0.044 14.1 0.0 4.8 1 1 4 5 5 5 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 OQS05702.1 - 1.9e-10 41.2 0.1 1.3e-05 25.7 0.0 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQS05702.1 - 1.3e-09 38.4 0.1 0.023 15.3 0.0 3.1 3 0 0 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQS05702.1 - 2.3e-06 27.5 0.0 0.75 10.6 0.0 4.2 4 1 0 4 4 4 1 Ankyrin repeat DUF3310 PF11753.8 OQS05702.1 - 0.044 14.0 0.1 0.23 11.7 0.1 2.1 1 1 1 2 2 2 0 Protein of unknwon function (DUF3310) DUF5454 PF17535.2 OQS05702.1 - 0.059 12.8 0.0 0.076 12.4 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5454) DUF3447 PF11929.8 OQS05702.1 - 0.066 13.2 0.5 0.74 9.8 0.2 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF3447) Orthopox_F8 PF05886.11 OQS05702.1 - 0.14 12.3 0.0 0.31 11.2 0.0 1.6 1 0 0 1 1 1 0 Orthopoxvirus F8 protein Barwin PF00967.17 OQS05703.1 - 0.016 15.0 0.9 0.039 13.8 0.9 1.7 1 0 0 1 1 1 0 Barwin family DPBB_1 PF03330.18 OQS05703.1 - 0.022 15.0 0.2 0.071 13.4 0.1 1.8 2 0 0 2 2 2 0 Lytic transglycolase Pkinase PF00069.25 OQS05704.1 - 2.6e-67 227.0 0.0 3.7e-67 226.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQS05704.1 - 9.2e-31 107.1 0.0 1.5e-30 106.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase DSPc PF00782.20 OQS05704.1 - 9.3e-25 87.0 0.0 2.2e-24 85.8 0.0 1.7 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain ASCH PF04266.14 OQS05704.1 - 2.1e-10 41.1 0.4 1.5e-09 38.4 0.0 2.5 3 0 0 3 3 2 1 ASCH domain Kinase-like PF14531.6 OQS05704.1 - 6.6e-07 28.9 0.0 4.4e-05 22.9 0.0 2.2 2 0 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 OQS05704.1 - 6.7e-05 22.0 0.1 0.00023 20.2 0.0 1.7 1 1 0 2 2 2 1 Haspin like kinase domain Y_phosphatase2 PF03162.13 OQS05704.1 - 0.00016 21.3 0.0 0.00037 20.1 0.0 1.5 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 OQS05704.1 - 0.0054 16.3 0.0 0.014 15.0 0.0 1.6 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Seadorna_VP7 PF07387.11 OQS05704.1 - 0.012 14.6 0.0 0.022 13.8 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 Init_tRNA_PT PF04179.12 OQS05704.1 - 0.052 13.8 0.0 0.17 12.2 0.0 1.8 1 0 0 1 1 1 0 Rit1 DUSP-like domain Kdo PF06293.14 OQS05704.1 - 0.06 12.7 0.1 0.1 11.9 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OQS05704.1 - 0.15 11.9 0.1 0.41 10.5 0.1 1.7 2 0 0 2 2 2 0 Phosphotransferase enzyme family Pkinase PF00069.25 OQS05705.1 - 4.5e-28 98.3 0.0 5.6e-28 98.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQS05705.1 - 1.1e-14 54.3 0.0 3.4e-14 52.8 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 OQS05705.1 - 0.0076 15.6 0.0 0.012 15.0 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 OQS05705.1 - 0.019 13.8 0.1 0.03 13.1 0.1 1.3 1 0 0 1 1 1 0 Fungal protein kinase Kinase-like PF14531.6 OQS05705.1 - 0.045 13.1 0.0 1.4 8.1 0.0 2.1 2 0 0 2 2 2 0 Kinase-like APH PF01636.23 OQS05705.1 - 0.062 13.2 0.2 0.38 10.6 0.0 2.0 2 1 0 3 3 3 0 Phosphotransferase enzyme family Acetyltransf_1 PF00583.25 OQS05706.1 - 1.3e-12 48.0 0.0 3.2e-12 46.7 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family TPR_12 PF13424.6 OQS05706.1 - 1.7e-08 34.6 2.9 1.7e-05 25.0 2.4 3.1 3 0 0 3 3 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 OQS05706.1 - 1.7e-05 24.6 0.7 1.4 9.3 0.1 4.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 OQS05706.1 - 6.2e-05 22.8 0.2 5.1 7.4 0.0 4.1 3 0 0 3 3 3 2 Tetratricopeptide repeat Acetyltransf_7 PF13508.7 OQS05706.1 - 7.4e-05 23.1 0.0 0.0002 21.7 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 OQS05706.1 - 0.00011 22.9 0.0 0.00024 21.8 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain TPR_1 PF00515.28 OQS05706.1 - 0.00014 21.5 2.1 0.2 11.5 0.1 3.9 4 0 0 4 4 4 2 Tetratricopeptide repeat Acetyltransf_10 PF13673.7 OQS05706.1 - 0.00054 19.9 0.0 0.0014 18.6 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain TPR_16 PF13432.6 OQS05706.1 - 0.00069 20.2 1.4 0.98 10.1 0.5 3.6 3 2 1 4 4 3 2 Tetratricopeptide repeat Acetyltransf_9 PF13527.7 OQS05706.1 - 0.0011 19.0 0.0 0.012 15.7 0.0 2.5 3 0 0 3 3 3 1 Acetyltransferase (GNAT) domain TPR_14 PF13428.6 OQS05706.1 - 0.0044 17.7 1.2 61 4.8 0.0 4.6 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_8 PF13181.6 OQS05706.1 - 0.0085 16.2 0.7 7 7.1 0.0 3.8 4 0 0 4 4 3 1 Tetratricopeptide repeat Rapsyn_N PF10579.9 OQS05706.1 - 0.049 13.7 0.0 0.13 12.3 0.0 1.7 1 0 0 1 1 1 0 Rapsyn N-terminal myristoylation and linker region TPR_10 PF13374.6 OQS05706.1 - 0.077 12.9 0.8 14 5.7 0.1 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat Acetyltransf_6 PF13480.7 OQS05706.1 - 0.089 12.9 0.2 0.2 11.8 0.2 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 OQS05706.1 - 0.09 12.9 0.0 0.21 11.7 0.0 1.6 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Pkinase PF00069.25 OQS05707.1 - 7.1e-67 225.6 0.0 1e-66 225.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQS05707.1 - 4.2e-39 134.4 0.0 5.9e-39 133.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase LON_substr_bdg PF02190.16 OQS05707.1 - 1.2e-12 48.2 0.3 1.9e-11 44.2 0.0 3.1 3 1 0 3 3 3 1 ATP-dependent protease La (LON) substrate-binding domain Yippee-Mis18 PF03226.14 OQS05707.1 - 1.4e-08 34.9 0.7 3.1e-08 33.8 0.7 1.6 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Kinase-like PF14531.6 OQS05707.1 - 3.2e-06 26.7 0.0 5.1e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 OQS05707.1 - 0.041 13.2 0.3 0.075 12.4 0.3 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 OQS05707.1 - 0.053 13.1 0.9 0.13 11.8 0.9 1.6 1 0 0 1 1 1 0 RIO1 family APH PF01636.23 OQS05707.1 - 0.29 11.0 0.6 1.9 8.4 0.0 2.4 2 1 1 3 3 3 0 Phosphotransferase enzyme family HSP70 PF00012.20 OQS05708.1 - 1.6e-40 138.9 1.2 6.2e-40 137.0 0.1 1.8 1 1 1 2 2 2 1 Hsp70 protein FGGY_C PF02782.16 OQS05708.1 - 0.053 13.2 0.0 0.096 12.4 0.0 1.4 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain PRK PF00485.18 OQS05709.1 - 5e-07 29.6 0.0 3e-06 27.1 0.0 2.0 1 1 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family SRP54 PF00448.22 OQS05709.1 - 8.9e-05 22.2 0.0 0.00015 21.4 0.0 1.3 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain MeaB PF03308.16 OQS05709.1 - 0.006 15.6 0.0 0.0096 14.9 0.0 1.2 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB MobB PF03205.14 OQS05709.1 - 0.073 13.0 0.1 2 8.3 0.0 2.5 2 1 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B DUF3146 PF11344.8 OQS05709.1 - 0.13 12.0 0.1 0.56 9.9 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3146) AAA_18 PF13238.6 OQS05709.1 - 0.21 12.1 0.0 0.77 10.3 0.0 1.9 2 0 0 2 2 2 0 AAA domain Mo25 PF08569.11 OQS05710.1 - 2e-121 405.4 10.4 2.3e-121 405.2 10.4 1.0 1 0 0 1 1 1 1 Mo25-like NleF_casp_inhib PF16809.5 OQS05711.1 - 0.016 15.1 1.2 0.22 11.4 0.0 2.5 2 2 0 2 2 2 0 NleF caspase inhibitor Prismane PF03063.20 OQS05712.1 - 1.6e-110 370.2 0.0 2.2e-110 369.8 0.0 1.1 1 0 0 1 1 1 1 Prismane/CO dehydrogenase family FAD_binding_1 PF00667.20 OQS05712.1 - 5.6e-37 127.5 0.0 9.7e-37 126.7 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 OQS05712.1 - 6e-25 88.1 0.0 1.2e-24 87.1 0.0 1.6 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.21 OQS05712.1 - 5.5e-07 30.2 0.0 1.4e-06 28.9 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Flavodoxin_5 PF12724.7 OQS05712.1 - 0.2 11.9 0.0 0.59 10.4 0.0 1.8 2 0 0 2 2 2 0 Flavodoxin domain UBA PF00627.31 OQS05713.1 - 2e-29 101.0 13.6 6.6e-16 57.9 0.1 4.1 4 0 0 4 4 4 2 UBA/TS-N domain XPC-binding PF09280.11 OQS05713.1 - 1.1e-23 82.7 10.1 1.1e-23 82.7 10.1 3.3 2 1 1 3 3 3 1 XPC-binding domain CUE PF02845.16 OQS05713.1 - 0.0026 17.4 5.0 1.2 8.9 0.0 3.3 4 0 0 4 4 4 2 CUE domain DnaB_2 PF07261.11 OQS05713.1 - 0.078 12.7 0.0 14 5.6 0.0 3.1 3 0 0 3 3 3 0 Replication initiation and membrane attachment DUF3617 PF12276.8 OQS05713.1 - 0.11 12.8 10.9 48 4.3 10.7 2.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3617) DUF1421 PF07223.11 OQS05713.1 - 0.15 11.9 0.0 1.4 8.8 0.0 2.4 2 0 0 2 2 2 0 UBA-like domain (DUF1421) DUF3135 PF11333.8 OQS05713.1 - 0.17 12.1 0.1 0.17 12.1 0.1 3.0 2 2 0 2 2 2 0 Protein of unknown function (DUF3135) YdaS_antitoxin PF15943.5 OQS05713.1 - 0.17 11.7 0.0 0.4 10.6 0.0 1.6 1 0 0 1 1 1 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT NIT PF08376.10 OQS05713.1 - 0.29 11.6 1.8 2.6 8.4 2.7 2.0 1 1 1 2 2 2 0 Nitrate and nitrite sensing Metal_resist PF13801.6 OQS05713.1 - 1.4 9.1 13.1 0.25 11.5 5.4 3.2 2 1 1 3 3 3 0 Heavy-metal resistance Gly_kinase PF02595.15 OQS05713.1 - 1.6 7.7 6.7 8.7 5.2 0.1 2.2 2 0 0 2 2 2 0 Glycerate kinase family FliJ PF02050.16 OQS05713.1 - 5.9 7.1 10.7 1.4 9.2 7.0 1.8 2 0 0 2 2 2 0 Flagellar FliJ protein DnaJ_C PF01556.18 OQS05714.1 - 3.3e-28 98.6 0.5 6.5e-28 97.7 0.1 1.6 2 0 0 2 2 2 1 DnaJ C terminal domain DnaJ PF00226.31 OQS05714.1 - 5.3e-27 93.7 0.6 8.6e-27 93.1 0.6 1.3 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 OQS05714.1 - 2.8e-14 53.2 18.2 4.9e-14 52.4 18.2 1.4 1 0 0 1 1 1 1 DnaJ central domain HypA PF01155.19 OQS05714.1 - 2.7e-05 24.1 6.1 0.045 13.8 0.5 2.3 2 0 0 2 2 2 2 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Anti-TRAP PF15777.5 OQS05714.1 - 4.7e-05 23.3 9.4 0.0071 16.3 1.1 2.3 2 0 0 2 2 2 2 Tryptophan RNA-binding attenuator protein inhibitory protein DZR PF12773.7 OQS05714.1 - 0.0094 16.0 9.8 0.016 15.3 9.8 1.4 1 0 0 1 1 1 1 Double zinc ribbon zf-RING_10 PF16685.5 OQS05714.1 - 0.86 9.8 5.7 1 9.5 0.2 2.5 2 0 0 2 2 2 0 zinc RING finger of MSL2 RseC_MucC PF04246.12 OQS05714.1 - 8 6.4 11.4 1.9 8.5 0.4 2.6 3 0 0 3 3 3 0 Positive regulator of sigma(E), RseC/MucC TackOD1 PF18551.1 OQS05714.1 - 8.1 6.1 8.6 7.4 6.2 0.8 2.2 1 1 1 2 2 2 0 Thaumarchaeal output domain 1 IRK_C PF17655.1 OQS05715.1 - 9.9e-26 90.4 0.1 4.6e-13 49.1 0.0 2.2 2 0 0 2 2 2 2 Inward rectifier potassium channel C-terminal domain IRK PF01007.20 OQS05715.1 - 4.5e-10 39.5 10.2 2.9e-09 36.8 10.2 2.1 1 1 0 1 1 1 1 Inward rectifier potassium channel transmembrane domain Ion_trans_2 PF07885.16 OQS05715.1 - 0.0005 20.0 8.2 0.001 19.0 8.2 1.5 1 0 0 1 1 1 1 Ion channel HA PF03457.14 OQS05716.1 - 1.7e-38 130.7 0.0 7.4e-09 35.8 0.0 4.4 4 0 0 4 4 4 4 Helicase associated domain P22_Cro PF14549.6 OQS05716.1 - 0.013 15.3 0.0 2.5 8.0 0.0 3.2 3 0 0 3 3 3 0 DNA-binding transcriptional regulator Cro Wx5_PLAF3D7 PF09688.10 OQS05716.1 - 0.82 9.7 8.3 2.1 8.3 0.2 3.3 3 0 0 3 3 3 0 Protein of unknown function (Wx5_PLAF3D7) SNARE_assoc PF09335.11 OQS05717.1 - 1.3e-14 54.7 9.2 1.3e-14 54.7 9.2 2.2 3 0 0 3 3 3 1 SNARE associated Golgi protein AAA_lid_2 PF17863.1 OQS05718.1 - 0.077 12.8 0.2 0.18 11.7 0.0 1.7 2 0 0 2 2 2 0 AAA lid domain DUF5133 PF17196.4 OQS05718.1 - 0.081 13.1 0.4 0.15 12.3 0.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF5133) Phage_T4_gp19 PF06841.12 OQS05719.1 - 0.066 13.1 0.0 0.091 12.6 0.0 1.3 1 0 0 1 1 1 0 T4-like virus tail tube protein gp19 DDE_3 PF13358.6 OQS05719.1 - 0.16 11.7 0.2 4.5 7.0 0.2 2.2 1 1 0 1 1 1 0 DDE superfamily endonuclease ARL2_Bind_BART PF11527.8 OQS05720.1 - 2.4e-27 95.4 7.8 2.9e-27 95.1 7.8 1.1 1 0 0 1 1 1 1 The ARF-like 2 binding protein BART Hemocyanin_N PF03722.14 OQS05720.1 - 0.0086 16.6 0.2 0.026 15.0 0.2 1.8 1 1 0 1 1 1 1 Hemocyanin, all-alpha domain Caleosin PF05042.13 OQS05720.1 - 0.04 13.9 0.1 0.19 11.6 0.0 1.8 1 1 1 2 2 2 0 Caleosin related protein GSH_synth_ATP PF03917.17 OQS05721.1 - 6.4e-119 397.1 0.0 7.4e-119 396.9 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic glutathione synthase, ATP binding domain GSH_synthase PF03199.15 OQS05721.1 - 6.5e-36 122.9 0.3 2e-35 121.3 0.4 1.8 2 0 0 2 2 2 1 Eukaryotic glutathione synthase XPC-binding PF09280.11 OQS05721.1 - 0.055 13.2 0.7 6.3 6.6 0.0 3.1 3 0 0 3 3 3 0 XPC-binding domain VWA PF00092.28 OQS05722.1 - 5.1e-25 88.7 0.1 1e-24 87.7 0.1 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.6 OQS05722.1 - 2.4e-14 53.5 0.0 1e-13 51.5 0.0 2.0 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA_2 PF13519.6 OQS05722.1 - 1.1e-11 45.4 0.1 3.8e-11 43.6 0.0 2.0 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA_CoxE PF05762.14 OQS05722.1 - 0.0015 18.0 0.0 0.0034 16.8 0.0 1.6 1 0 0 1 1 1 1 VWA domain containing CoxE-like protein DUF2201 PF09967.9 OQS05722.1 - 0.0063 16.7 1.1 0.03 14.5 0.0 2.3 2 0 0 2 2 2 1 VWA-like domain (DUF2201) Kazal_2 PF07648.15 OQS05722.1 - 0.0094 16.1 0.1 0.026 14.7 0.1 1.7 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain CobT_C PF11775.8 OQS05722.1 - 0.042 13.5 0.1 0.13 11.9 0.0 1.8 2 0 0 2 2 2 0 Cobalamin biosynthesis protein CobT VWA domain Vwaint PF14624.6 OQS05722.1 - 0.11 12.7 0.5 0.23 11.6 0.5 1.5 1 0 0 1 1 1 0 VWA / Hh protein intein-like Hydrolase_4 PF12146.8 OQS05723.1 - 1.1e-52 178.7 0.0 1.3e-52 178.5 0.0 1.0 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 OQS05723.1 - 9.4e-17 62.3 0.0 1.2e-16 62.0 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 OQS05723.1 - 4.5e-16 59.3 0.1 3.4e-14 53.1 0.1 2.0 1 1 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 OQS05723.1 - 4.6e-10 39.3 0.0 0.00062 19.3 0.0 2.1 2 0 0 2 2 2 2 Prolyl oligopeptidase family DLH PF01738.18 OQS05723.1 - 8.7e-05 22.2 0.0 0.12 11.9 0.0 2.1 2 0 0 2 2 2 2 Dienelactone hydrolase family BAAT_C PF08840.11 OQS05723.1 - 0.0014 18.6 0.0 0.024 14.6 0.0 2.3 2 1 0 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_2 PF02230.16 OQS05723.1 - 0.0017 18.2 0.0 0.049 13.4 0.0 2.5 3 0 0 3 3 3 1 Phospholipase/Carboxylesterase Peptidase_S15 PF02129.18 OQS05723.1 - 0.0045 16.6 0.0 0.011 15.3 0.0 1.9 1 1 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Chlorophyllase PF07224.11 OQS05723.1 - 0.026 13.5 0.1 0.89 8.5 0.0 2.1 2 0 0 2 2 2 0 Chlorophyllase FSH1 PF03959.13 OQS05723.1 - 0.039 13.6 0.1 0.15 11.7 0.0 1.9 2 1 0 2 2 2 0 Serine hydrolase (FSH1) Chlorophyllase2 PF12740.7 OQS05723.1 - 0.076 11.9 0.0 0.25 10.2 0.0 1.8 2 0 0 2 2 2 0 Chlorophyllase enzyme CheB_methylest PF01339.17 OQS05724.1 - 0.077 12.7 0.0 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 CheB methylesterase Ank_2 PF12796.7 OQS05725.1 - 0 1100.8 105.3 3.2e-19 69.3 0.3 29.9 3 3 28 31 31 31 31 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQS05725.1 - 8e-255 820.3 81.7 4e-09 36.8 0.0 40.9 16 12 25 43 43 43 43 Ankyrin repeats (many copies) Ank PF00023.30 OQS05725.1 - 6.2e-241 769.5 169.4 1.4e-05 25.3 0.0 56.3 55 2 2 57 57 57 50 Ankyrin repeat Ank_3 PF13606.6 OQS05725.1 - 9.1e-193 600.2 92.5 0.00051 20.3 0.0 55.4 57 0 0 57 57 57 43 Ankyrin repeat Ank_5 PF13857.6 OQS05725.1 - 4.4e-171 552.7 106.2 4.7e-08 33.1 0.2 38.3 13 9 34 47 47 47 42 Ankyrin repeats (many copies) YfmQ PF10787.9 OQS05725.1 - 8.5e-15 54.8 0.0 52 3.6 0.0 20.1 20 7 8 28 28 28 0 Uncharacterised protein from bacillus cereus group Mon1 PF03164.14 OQS05725.1 - 1.5e-07 30.9 0.0 8.7 5.3 0.0 7.8 9 1 1 10 10 10 1 Trafficking protein Mon1 HEM4 PF02602.15 OQS05725.1 - 7.9e-07 28.7 0.0 39 3.5 0.0 8.8 7 2 2 10 10 10 0 Uroporphyrinogen-III synthase HemD zf-dskA_traR PF01258.17 OQS05725.1 - 8.8e-06 25.6 1.2 94 3.1 0.0 9.3 12 0 0 12 12 10 0 Prokaryotic dksA/traR C4-type zinc finger Sulfotransfer_4 PF17784.1 OQS05725.1 - 2.5e-05 24.2 0.0 26 4.6 0.0 8.5 11 1 1 12 12 12 0 Sulfotransferase domain ATPase PF06745.13 OQS05725.1 - 3.1e-05 23.4 0.0 6.8 6.0 0.0 6.1 6 2 1 7 7 7 1 KaiC Env-gp36 PF09590.10 OQS05725.1 - 0.017 13.6 1.0 3.5 5.9 0.0 3.8 4 0 0 4 4 4 0 Lentivirus surface glycoprotein PK_C PF02887.16 OQS05725.1 - 0.047 13.9 0.3 18 5.6 0.0 5.1 6 1 0 6 6 6 0 Pyruvate kinase, alpha/beta domain Response_reg PF00072.24 OQS05725.1 - 0.11 12.6 0.4 9.8 6.4 0.0 4.6 4 0 0 4 4 3 0 Response regulator receiver domain DUF4398 PF14346.6 OQS05725.1 - 0.19 12.4 5.3 1.5e+02 3.1 0.0 6.5 6 0 0 6 6 6 0 Domain of unknown function (DUF4398) DUF4712 PF15830.5 OQS05726.1 - 0.043 13.5 0.1 0.043 13.5 0.1 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4712) LSM PF01423.22 OQS05727.1 - 6.1e-17 61.1 0.5 9e-17 60.5 0.2 1.4 2 0 0 2 2 2 1 LSM domain SM-ATX PF14438.6 OQS05727.1 - 0.00029 20.9 0.0 0.00046 20.3 0.0 1.3 1 0 0 1 1 1 1 Ataxin 2 SM domain Feld-I_B PF09252.10 OQS05727.1 - 0.17 11.8 0.0 0.27 11.2 0.0 1.3 1 0 0 1 1 1 0 Allergen Fel d I-B chain Dpy-30 PF05186.13 OQS05728.1 - 3.9e-19 68.1 0.3 5.3e-19 67.6 0.3 1.2 1 0 0 1 1 1 1 Dpy-30 motif DUF4678 PF15727.5 OQS05728.1 - 0.033 13.5 2.2 0.035 13.4 2.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4678) HD_3 PF13023.6 OQS05729.1 - 4.9e-48 163.2 1.7 5.8e-48 162.9 1.7 1.0 1 0 0 1 1 1 1 HD domain HD_2 PF12917.7 OQS05729.1 - 1e-13 51.5 1.0 1.3e-13 51.1 1.0 1.2 1 0 0 1 1 1 1 HD containing hydrolase-like enzyme HD PF01966.22 OQS05729.1 - 0.00015 22.0 1.3 0.00023 21.4 1.3 1.3 1 0 0 1 1 1 1 HD domain ADK PF00406.22 OQS05730.1 - 2e-59 200.0 0.0 2.6e-59 199.7 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 OQS05730.1 - 4.1e-25 88.8 0.2 1.1e-24 87.3 0.0 1.7 2 0 0 2 2 2 1 AAA domain ADK_lid PF05191.14 OQS05730.1 - 1.6e-18 66.3 0.0 3.1e-18 65.5 0.0 1.5 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_33 PF13671.6 OQS05730.1 - 0.00022 21.4 0.0 0.0004 20.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 OQS05730.1 - 0.058 13.9 0.1 0.19 12.3 0.0 1.9 2 0 0 2 2 2 0 AAA domain RuvB_N PF05496.12 OQS05730.1 - 0.093 12.5 0.0 0.31 10.8 0.0 1.8 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain DUF1627 PF07789.12 OQS05731.1 - 0.14 11.8 0.0 0.21 11.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1627) MMgT PF10270.9 OQS05732.1 - 1.9e-06 28.2 0.0 2.1e-06 28.0 0.0 1.1 1 0 0 1 1 1 1 Membrane magnesium transporter Complex1_LYR PF05347.15 OQS05733.1 - 2.3e-15 56.3 1.0 4.2e-15 55.5 1.0 1.4 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 OQS05733.1 - 2e-06 28.4 0.1 2.6e-06 28.1 0.1 1.1 1 0 0 1 1 1 1 Complex1_LYR-like LisH_2 PF16045.5 OQS05734.1 - 1.4e-09 36.8 0.0 3.1e-09 35.7 0.0 1.6 2 0 0 2 2 2 1 LisH RIH_assoc PF08454.11 OQS05735.1 - 1.9e-16 59.7 1.3 6.7e-16 58.0 1.3 2.0 1 0 0 1 1 1 1 RyR and IP3R Homology associated Ion_trans PF00520.31 OQS05735.1 - 1.4e-09 37.6 13.2 1.4e-09 37.6 13.2 2.8 2 1 1 3 3 3 1 Ion transport protein Ank_2 PF12796.7 OQS05735.1 - 0.0048 17.5 0.1 0.015 15.9 0.1 1.8 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) PDEase_I PF00233.19 OQS05736.1 - 1.4e-51 175.6 6.0 1.8e-51 175.2 6.0 1.1 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase DUF1508 PF07411.12 OQS05736.1 - 0.024 14.5 0.3 3.4 7.6 0.0 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF1508) HD PF01966.22 OQS05736.1 - 0.033 14.4 0.7 0.083 13.1 0.7 1.7 1 1 0 1 1 1 0 HD domain RIH_assoc PF08454.11 OQS05737.1 - 4.6e-14 52.1 1.3 2.3e-13 49.9 0.9 2.4 2 0 0 2 2 2 1 RyR and IP3R Homology associated Ion_trans PF00520.31 OQS05737.1 - 1.8e-09 37.2 15.0 1.8e-09 37.2 15.0 2.2 2 0 0 2 2 2 1 Ion transport protein BTB PF00651.31 OQS05738.1 - 7.5e-24 84.1 0.3 2.9e-21 75.7 0.0 2.3 1 1 1 2 2 2 2 BTB/POZ domain HEPN_AbiV PF18728.1 OQS05738.1 - 0.013 15.7 0.0 0.027 14.6 0.0 1.5 1 0 0 1 1 1 0 AbiV Rad60-SLD PF11976.8 OQS05738.1 - 0.015 15.1 0.0 0.027 14.3 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like BACK PF07707.15 OQS05738.1 - 0.034 14.3 0.7 0.16 12.1 0.1 2.2 2 0 0 2 2 2 0 BTB And C-terminal Kelch PQ-loop PF04193.14 OQS05739.1 - 1.5e-36 124.0 21.4 1.3e-18 66.6 0.5 2.8 3 0 0 3 3 3 2 PQ loop repeat TrbC PF04956.13 OQS05739.1 - 0.06 13.6 2.9 0.11 12.8 0.1 2.6 3 0 0 3 3 3 0 TrbC/VIRB2 family WD40 PF00400.32 OQS05740.1 - 1.7e-06 28.6 15.9 0.22 12.4 0.0 7.0 7 0 0 7 7 7 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OQS05740.1 - 2.3e-06 27.8 0.0 5.2 7.4 0.0 5.0 4 1 0 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Oxidored_FMN PF00724.20 OQS05741.1 - 1.4e-87 294.2 0.0 1.6e-87 294.0 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family AP_endonuc_2 PF01261.24 OQS05741.1 - 0.012 15.0 0.1 0.7 9.3 0.0 2.5 2 1 1 3 3 3 0 Xylose isomerase-like TIM barrel Tautomerase PF01361.21 OQS05741.1 - 0.17 11.9 0.0 0.45 10.5 0.0 1.7 1 0 0 1 1 1 0 Tautomerase enzyme B12D PF06522.11 OQS05742.1 - 4.2e-11 42.5 0.0 5.1e-11 42.2 0.0 1.2 1 0 0 1 1 1 1 NADH-ubiquinone reductase complex 1 MLRQ subunit LSM PF01423.22 OQS05743.1 - 1.1e-20 73.1 0.9 1.4e-20 72.7 0.9 1.1 1 0 0 1 1 1 1 LSM domain DUF1336 PF07059.12 OQS05744.1 - 1.7e-55 188.6 0.0 3.5e-55 187.5 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1336) Kelch_1 PF01344.25 OQS05744.1 - 3.9e-45 151.2 12.6 9.8e-10 37.9 0.6 7.2 7 0 0 7 7 7 5 Kelch motif Kelch_6 PF13964.6 OQS05744.1 - 7.7e-36 121.2 7.6 5.8e-08 32.7 0.0 6.8 2 2 4 6 6 6 5 Kelch motif STIMATE PF12400.8 OQS05744.1 - 1.3e-34 119.5 6.0 2.9e-34 118.3 6.0 1.7 1 0 0 1 1 1 1 STIMATE family Kelch_2 PF07646.15 OQS05744.1 - 3.2e-19 68.1 9.7 4.6e-07 29.6 0.0 5.6 6 0 0 6 6 6 4 Kelch motif Kelch_3 PF13415.6 OQS05744.1 - 3.8e-19 68.5 7.2 0.00015 22.0 0.1 6.1 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_4 PF13418.6 OQS05744.1 - 1.6e-16 60.0 1.5 0.0066 16.4 0.1 5.7 5 0 0 5 5 5 4 Galactose oxidase, central domain START PF01852.19 OQS05744.1 - 2.9e-14 53.0 0.5 5.6e-14 52.0 0.5 1.4 1 0 0 1 1 1 1 START domain Kelch_5 PF13854.6 OQS05744.1 - 2.6e-05 24.1 8.8 1.7 8.7 0.1 5.5 5 0 0 5 5 5 2 Kelch motif PH PF00169.29 OQS05744.1 - 3.5e-05 24.2 0.7 0.00011 22.7 0.1 2.2 2 0 0 2 2 2 1 PH domain Ank_2 PF12796.7 OQS05745.1 - 4.1e-26 91.4 8.5 1.4e-13 51.2 0.1 3.0 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OQS05745.1 - 7.3e-21 72.0 1.0 1.4e-06 28.2 0.1 4.3 4 0 0 4 4 4 4 Ankyrin repeat Ank_5 PF13857.6 OQS05745.1 - 2.2e-20 72.4 4.5 1.2e-08 35.1 0.1 3.8 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank_4 PF13637.6 OQS05745.1 - 9e-19 67.6 0.6 4.3e-12 46.3 0.1 3.5 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 OQS05745.1 - 1.3e-18 66.5 4.6 1.8e-08 34.4 0.1 4.5 4 1 0 4 4 4 4 Ankyrin repeat B12D PF06522.11 OQS05746.1 - 3.3e-14 52.4 0.0 4.1e-14 52.1 0.0 1.3 1 0 0 1 1 1 1 NADH-ubiquinone reductase complex 1 MLRQ subunit KLRAQ PF10205.9 OQS05747.1 - 0.0075 16.5 0.9 0.0075 16.5 0.9 2.4 2 0 0 2 2 2 1 Predicted coiled-coil domain-containing protein Jnk-SapK_ap_N PF09744.9 OQS05747.1 - 0.32 11.2 15.5 0.53 10.5 5.6 3.2 2 1 0 2 2 2 0 JNK_SAPK-associated protein-1 DivIC PF04977.15 OQS05747.1 - 0.33 10.7 4.8 0.48 10.2 0.2 2.7 2 0 0 2 2 2 0 Septum formation initiator SlyX PF04102.12 OQS05747.1 - 0.43 11.2 3.9 0.63 10.7 0.4 3.0 2 0 0 2 2 2 0 SlyX TSC22 PF01166.18 OQS05747.1 - 0.78 10.1 4.6 16 5.9 0.2 2.9 2 0 0 2 2 2 0 TSC-22/dip/bun family Cnn_1N PF07989.11 OQS05747.1 - 2.7 8.2 6.7 0.88 9.8 0.3 2.9 3 0 0 3 3 3 0 Centrosomin N-terminal motif 1 Spc24 PF08286.11 OQS05747.1 - 4.2 7.7 8.6 2.2 8.6 1.8 2.6 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 BT1 PF03092.16 OQS05748.1 - 1.2e-10 40.3 2.2 1.2e-10 40.3 2.2 2.9 3 0 0 3 3 3 2 BT1 family TPR_1 PF00515.28 OQS05749.1 - 1.2e-13 50.3 5.1 0.00092 18.9 0.0 5.0 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.17 OQS05749.1 - 1.7e-13 49.5 4.1 0.0067 16.5 0.0 5.1 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_11 PF13414.6 OQS05749.1 - 5.9e-10 38.7 0.9 7.9e-05 22.3 0.0 4.3 4 1 1 5 5 5 2 TPR repeat TPR_17 PF13431.6 OQS05749.1 - 2.4e-09 36.9 0.4 0.035 14.5 0.0 5.1 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.6 OQS05749.1 - 8.4e-09 35.6 6.0 0.0002 21.6 0.2 4.4 3 2 1 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 OQS05749.1 - 1e-08 34.7 3.6 0.85 10.0 0.0 4.8 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_7 PF13176.6 OQS05749.1 - 2.6e-08 33.3 5.2 0.1 12.7 0.0 4.8 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_19 PF14559.6 OQS05749.1 - 4e-08 33.7 4.3 1.6e-06 28.5 0.1 3.6 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.6 OQS05749.1 - 1.1e-07 32.0 1.8 0.059 14.2 0.0 4.7 2 1 3 5 5 5 2 Tetratricopeptide repeat TPR_9 PF13371.6 OQS05749.1 - 4.6e-06 26.7 0.2 0.0014 18.7 0.1 3.1 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 OQS05749.1 - 3.6e-05 24.3 1.3 0.0071 17.0 0.0 3.3 3 1 1 4 4 3 2 Tetratricopeptide repeat Alkyl_sulf_dimr PF14863.6 OQS05749.1 - 0.0015 19.0 0.1 0.019 15.4 0.1 2.2 1 1 1 2 2 2 1 Alkyl sulfatase dimerisation TPR_MalT PF17874.1 OQS05749.1 - 0.0054 16.2 0.2 0.038 13.4 0.1 2.2 1 1 1 2 2 2 1 MalT-like TPR region TPR_15 PF13429.6 OQS05749.1 - 0.0069 15.6 0.5 0.021 14.0 0.1 1.6 1 1 0 1 1 1 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 OQS05749.1 - 0.014 15.5 0.1 2.2 8.4 0.0 2.7 3 0 0 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat NARP1 PF12569.8 OQS05749.1 - 0.014 14.3 1.6 0.016 14.2 0.5 1.5 2 0 0 2 2 2 0 NMDA receptor-regulated protein 1 DUF4919 PF16266.5 OQS05749.1 - 0.058 13.3 0.6 3.7 7.5 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4919) US6 PF17616.2 OQS05749.1 - 0.071 13.1 0.1 0.18 11.8 0.0 1.7 2 0 0 2 2 2 0 Viral unique short region 6 TPR_10 PF13374.6 OQS05749.1 - 0.082 12.8 8.9 8.2 6.5 0.0 4.7 6 0 0 6 6 5 0 Tetratricopeptide repeat Wzy_C_2 PF11846.8 OQS05749.1 - 0.09 12.7 0.3 0.19 11.6 0.1 1.6 2 0 0 2 2 2 0 Virulence factor membrane-bound polymerase, C-terminal TPR_6 PF13174.6 OQS05749.1 - 0.14 12.9 7.5 86 4.1 0.1 5.3 6 0 0 6 6 6 0 Tetratricopeptide repeat Acyltransferase PF01553.21 OQS05751.1 - 2.9e-17 62.6 0.0 4.5e-17 61.9 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase Acyltransf_C PF16076.5 OQS05751.1 - 3.9e-13 49.3 0.0 9.3e-13 48.1 0.0 1.6 1 0 0 1 1 1 1 Acyltransferase C-terminus Claudin_2 PF13903.6 OQS05751.1 - 0.0064 16.3 0.3 0.0064 16.3 0.3 2.2 2 1 1 3 3 3 1 PMP-22/EMP/MP20/Claudin tight junction Vma12 PF11712.8 OQS05751.1 - 2.2 8.3 4.3 0.59 10.2 0.7 1.9 2 0 0 2 2 2 0 Endoplasmic reticulum-based factor for assembly of V-ATPase TPR_12 PF13424.6 OQS05752.1 - 0.0011 19.2 4.8 0.0011 19.2 4.8 2.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_10 PF13374.6 OQS05752.1 - 0.1 12.5 10.6 0.93 9.4 0.6 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.28 OQS05752.1 - 0.24 11.3 17.3 0.19 11.6 0.6 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.6 OQS05752.1 - 2.6 9.1 4.9 3.1 8.8 0.5 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat ANAPC3 PF12895.7 OQS05752.1 - 4.9 7.4 10.2 1.5 9.1 6.0 2.3 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 ATPase PF06745.13 OQS05753.1 - 3.6e-07 29.8 0.0 5.5e-07 29.2 0.0 1.3 1 0 0 1 1 1 1 KaiC Rad51 PF08423.11 OQS05753.1 - 9.4e-06 25.1 0.0 1.1e-05 24.8 0.0 1.1 1 0 0 1 1 1 1 Rad51 ATPase_2 PF01637.18 OQS05753.1 - 0.014 15.3 0.0 0.019 14.9 0.0 1.2 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea RecA PF00154.21 OQS05753.1 - 0.037 13.5 0.0 0.058 12.8 0.0 1.2 1 0 0 1 1 1 0 recA bacterial DNA recombination protein BNR_2 PF13088.6 OQS05753.1 - 0.08 12.2 0.0 0.1 11.8 0.0 1.2 1 0 0 1 1 1 0 BNR repeat-like domain Ank_2 PF12796.7 OQS05755.1 - 3.1e-38 130.2 34.3 5.5e-06 26.9 0.4 11.0 1 1 12 14 14 14 14 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQS05755.1 - 7e-36 122.1 19.5 0.0007 20.1 0.0 13.8 8 5 3 12 12 12 9 Ankyrin repeats (many copies) Ank_5 PF13857.6 OQS05755.1 - 8.1e-29 99.3 26.0 0.0057 16.9 0.1 18.3 6 5 12 20 20 20 8 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQS05755.1 - 1.5e-15 55.7 20.3 4.8 8.1 0.1 17.4 23 0 0 23 23 23 3 Ankyrin repeat DUF5049 PF16468.5 OQS05755.1 - 1.5e-05 24.8 15.1 14 5.7 0.1 11.0 8 2 5 13 13 13 1 Domain of unknown function (DUF5049) BTHB PF18410.1 OQS05755.1 - 0.097 12.5 0.2 15 5.4 0.0 4.7 6 0 0 6 6 6 0 Basic tilted helix bundle domain DUF3447 PF11929.8 OQS05755.1 - 0.14 12.2 22.5 3.5 7.6 0.1 7.8 7 1 2 9 9 9 0 Domain of unknown function (DUF3447) Ank PF00023.30 OQS05755.1 - 0.37 11.3 12.3 1.1e+02 3.5 0.0 8.8 7 2 1 8 8 8 0 Ankyrin repeat DUF1843 PF08898.10 OQS05755.1 - 0.72 10.4 4.4 32 5.1 0.6 4.7 4 1 0 4 4 4 0 Domain of unknown function (DUF1843) Ank_4 PF13637.6 OQS05756.1 - 3e-05 24.5 0.3 0.036 14.7 0.0 3.2 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 OQS05756.1 - 0.00087 19.8 1.3 0.0037 17.8 0.1 2.2 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) Ank_2 PF12796.7 OQS05757.1 - 2.1e-18 66.6 10.1 2.1e-08 34.6 0.5 2.4 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OQS05757.1 - 2.8e-11 43.4 0.4 0.00031 21.0 0.0 3.3 1 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 OQS05757.1 - 1.7e-10 41.2 2.7 1.5e-06 28.6 0.1 2.8 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQS05757.1 - 6.4e-09 35.3 0.2 0.36 11.5 0.0 4.0 2 1 2 4 4 4 3 Ankyrin repeat DUF4031 PF13223.6 OQS05757.1 - 0.00048 20.3 1.1 1.7 8.9 0.2 3.0 2 1 1 3 3 3 2 Protein of unknown function (DUF4031) Ank PF00023.30 OQS05757.1 - 0.0067 16.8 0.5 25 5.5 0.1 3.5 2 2 1 3 3 3 0 Ankyrin repeat DUF5049 PF16468.5 OQS05757.1 - 0.037 13.9 0.0 10 6.1 0.0 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF5049) TPP_enzyme_C PF02775.21 OQS05757.1 - 0.1 12.4 0.0 1.2 8.9 0.0 2.1 1 1 1 2 2 2 0 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain APP_Cu_bd PF12924.7 OQS05757.1 - 0.22 12.3 2.1 21 6.0 0.1 2.6 2 1 0 2 2 2 0 Copper-binding of amyloid precursor, CuBD Abhydrolase_1 PF00561.20 OQS05759.1 - 1.1e-28 100.6 0.1 2.8e-28 99.3 0.1 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_4 PF08386.10 OQS05759.1 - 0.17 12.0 0.0 1.6 8.9 0.0 2.3 2 0 0 2 2 2 0 TAP-like protein C2 PF00168.30 OQS05760.1 - 2.5e-82 271.8 5.3 3.5e-18 65.8 0.0 7.5 7 0 0 7 7 7 6 C2 domain PI3K_C2 PF00792.24 OQS05760.1 - 0.0019 18.1 0.2 0.046 13.6 0.1 3.1 3 0 0 3 3 3 1 Phosphoinositide 3-kinase C2 FerI PF08151.12 OQS05760.1 - 0.02 15.0 0.0 0.095 12.8 0.0 2.2 1 0 0 1 1 1 0 FerI (NUC094) domain NT-C2 PF10358.9 OQS05760.1 - 0.091 12.5 6.2 0.24 11.1 0.1 3.7 5 0 0 5 5 5 0 N-terminal C2 in EEIG1 and EHBP1 proteins Ferlin_C PF16165.5 OQS05760.1 - 0.56 10.1 0.0 0.56 10.1 0.0 2.4 3 0 0 3 3 3 0 Ferlin C-terminus Sulfate_transp PF00916.20 OQS05761.1 - 5.3e-12 45.2 14.3 7.1e-10 38.2 14.3 2.3 1 1 0 1 1 1 1 Sulfate permease family STAS PF01740.21 OQS05761.1 - 0.0046 16.6 0.0 0.0085 15.7 0.0 1.3 1 0 0 1 1 1 1 STAS domain STAS_2 PF13466.6 OQS05761.1 - 0.043 14.2 0.0 0.085 13.2 0.0 1.5 1 0 0 1 1 1 0 STAS domain TMEM52 PF14979.6 OQS05762.1 - 0.00098 19.1 0.4 0.00098 19.1 0.4 2.1 1 1 1 2 2 2 1 Transmembrane 52 DUF4366 PF14283.6 OQS05762.1 - 0.055 13.5 4.2 0.35 10.9 4.2 2.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4366) TMEM154 PF15102.6 OQS05762.1 - 1.7 8.5 13.9 3 7.7 11.0 2.8 1 1 0 1 1 1 0 TMEM154 protein family FeoB_associated PF12669.7 OQS05762.1 - 6.8 7.2 5.6 13 6.3 5.6 1.4 1 0 0 1 1 1 0 FeoB-associated Cys-rich membrane protein TFIIA PF03153.13 OQS05762.1 - 8.1 6.3 24.0 18 5.2 24.0 1.6 1 1 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit RRM_1 PF00076.22 OQS05763.1 - 9.7e-17 60.6 0.0 1.7e-16 59.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 OQS05763.1 - 4e-08 32.9 0.0 4.9e-08 32.6 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Pkinase PF00069.25 OQS05764.1 - 7.5e-59 199.2 0.0 3.6e-58 197.0 0.0 2.1 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQS05764.1 - 1.1e-24 87.2 0.4 1.7e-17 63.6 0.3 2.4 2 0 0 2 2 2 2 Protein tyrosine kinase Haspin_kinase PF12330.8 OQS05764.1 - 0.00045 19.3 0.2 0.0011 17.9 0.2 1.6 1 1 0 1 1 1 1 Haspin like kinase domain Seadorna_VP7 PF07387.11 OQS05764.1 - 0.027 13.5 0.2 0.046 12.8 0.2 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 Pkinase_C PF00433.24 OQS05764.1 - 0.04 14.6 0.2 0.1 13.4 0.2 1.7 1 0 0 1 1 1 0 Protein kinase C terminal domain APH PF01636.23 OQS05764.1 - 0.047 13.6 0.3 0.43 10.4 0.1 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 OQS05764.1 - 0.063 12.0 2.1 0.12 11.2 2.1 1.5 1 1 0 1 1 1 0 Fungal protein kinase Kdo PF06293.14 OQS05764.1 - 0.13 11.6 0.0 0.13 11.6 0.0 2.1 3 0 0 3 3 3 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 OQS05764.1 - 0.19 11.0 1.5 0.24 10.7 0.2 2.0 2 1 0 2 2 2 0 Kinase-like Formyl_trans_N PF00551.19 OQS05765.1 - 2.2e-24 86.2 0.0 3.3e-24 85.6 0.0 1.3 1 0 0 1 1 1 1 Formyl transferase Formyl_trans_C PF02911.18 OQS05765.1 - 1.8e-12 47.3 0.0 3.5e-12 46.4 0.0 1.5 1 0 0 1 1 1 1 Formyl transferase, C-terminal domain DUF2183 PF09949.9 OQS05766.1 - 0.0029 17.9 0.0 0.014 15.7 0.0 2.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2183) HEM4 PF02602.15 OQS05767.1 - 1.7e-28 99.6 0.4 3.1e-28 98.7 0.4 1.4 1 1 0 1 1 1 1 Uroporphyrinogen-III synthase HemD ABC_tran PF00005.27 OQS05768.1 - 6.6e-42 143.3 0.0 2e-25 89.9 0.0 3.4 3 0 0 3 3 3 2 ABC transporter ABC_membrane PF00664.23 OQS05768.1 - 7.7e-42 143.8 25.1 1.1e-21 77.7 15.0 2.8 3 0 0 3 3 3 2 ABC transporter transmembrane region YdjM PF04307.14 OQS05768.1 - 5.7e-09 35.5 7.4 3.2e-08 33.1 7.4 2.4 1 0 0 1 1 1 1 LexA-binding, inner membrane-associated putative hydrolase SMC_N PF02463.19 OQS05768.1 - 4e-07 29.7 0.1 0.11 12.0 0.0 3.3 3 0 0 3 3 3 2 RecF/RecN/SMC N terminal domain DUF87 PF01935.17 OQS05768.1 - 0.0013 18.9 0.5 0.0033 17.6 0.2 1.8 2 0 0 2 2 2 1 Helicase HerA, central domain MMR_HSR1 PF01926.23 OQS05768.1 - 0.017 15.2 0.2 0.055 13.6 0.2 1.9 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_21 PF13304.6 OQS05768.1 - 0.047 13.5 2.9 7 6.4 0.1 3.2 2 1 1 3 3 3 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 OQS05768.1 - 0.065 13.0 0.0 1.9 8.3 0.1 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain DUF815 PF05673.13 OQS05768.1 - 0.19 10.9 0.0 0.38 9.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Mid1 PF12929.7 OQS05769.1 - 3.4e-12 46.3 14.3 6e-09 35.6 5.3 2.1 1 1 1 2 2 2 2 Stretch-activated Ca2+-permeable channel component Fz PF01392.22 OQS05769.1 - 3.1 8.5 11.8 21 5.8 11.8 2.2 1 1 0 1 1 1 0 Fz domain Pkinase PF00069.25 OQS05770.1 - 0.0012 18.2 0.0 0.0015 18.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain IFT46_B_C PF12317.8 OQS05771.1 - 1.4e-46 158.9 0.5 2.2e-46 158.3 0.5 1.2 1 0 0 1 1 1 1 Intraflagellar transport complex B protein 46 C terminal Pkinase_Tyr PF07714.17 OQS05772.1 - 1.8e-97 325.7 0.0 1.3e-47 162.3 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 OQS05772.1 - 1.1e-95 320.0 0.0 1.2e-46 159.2 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_fungal PF17667.1 OQS05772.1 - 2.3e-05 23.3 0.0 0.004 16.0 0.0 2.2 2 0 0 2 2 2 2 Fungal protein kinase APH PF01636.23 OQS05772.1 - 7.4e-05 22.8 0.0 0.58 10.0 0.0 2.7 3 0 0 3 3 3 2 Phosphotransferase enzyme family LRR_4 PF12799.7 OQS05772.1 - 0.00026 21.3 17.9 0.00035 20.9 6.9 5.2 3 2 5 8 8 8 3 Leucine Rich repeats (2 copies) Haspin_kinase PF12330.8 OQS05772.1 - 0.00048 19.2 0.7 1.1 8.1 0.0 3.5 5 0 0 5 5 5 2 Haspin like kinase domain Syndecan PF01034.20 OQS05772.1 - 0.0014 18.5 1.5 0.26 11.2 0.0 2.5 2 0 0 2 2 2 1 Syndecan domain EphA2_TM PF14575.6 OQS05772.1 - 0.002 19.0 0.0 4.8 8.1 0.0 2.8 3 0 0 3 3 2 2 Ephrin type-A receptor 2 transmembrane domain LRR_8 PF13855.6 OQS05772.1 - 0.012 15.3 16.8 0.016 14.9 3.4 3.9 2 1 1 3 3 3 0 Leucine rich repeat Kinase-like PF14531.6 OQS05772.1 - 0.042 13.2 0.0 6 6.1 0.0 2.2 2 0 0 2 2 2 0 Kinase-like TMEM154 PF15102.6 OQS05772.1 - 0.063 13.2 0.2 0.43 10.5 0.1 2.2 2 0 0 2 2 2 0 TMEM154 protein family Gram_pos_anchor PF00746.21 OQS05772.1 - 0.068 13.1 0.0 1.3 9.1 0.0 2.7 2 0 0 2 2 2 0 LPXTG cell wall anchor motif Orf78 PF06024.12 OQS05772.1 - 0.11 12.8 0.0 20 5.5 0.0 2.7 2 0 0 2 2 2 0 Orf78 (ac78) DUF4064 PF13273.6 OQS05772.1 - 0.13 12.5 6.3 0.82 10.0 0.1 2.9 3 0 0 3 3 2 0 Protein of unknown function (DUF4064) Adeno_E3_CR2 PF02439.15 OQS05772.1 - 0.2 11.4 5.1 0.51 10.2 1.0 2.6 2 0 0 2 2 2 0 Adenovirus E3 region protein CR2 LRR_6 PF13516.6 OQS05772.1 - 0.44 10.7 3.4 7.8 6.8 0.1 3.8 3 0 0 3 3 3 0 Leucine Rich repeat Thx PF17070.5 OQS05772.1 - 0.62 10.3 2.0 2.3 8.4 0.5 2.3 2 0 0 2 2 2 0 30S ribosomal protein Thx SKG6 PF08693.10 OQS05772.1 - 1.7 8.1 10.1 1.9 8.0 0.8 2.6 2 0 0 2 2 2 0 Transmembrane alpha-helix domain Gal-bind_lectin PF00337.22 OQS05773.1 - 1.4e-12 47.3 0.0 2.1e-12 46.8 0.0 1.2 1 0 0 1 1 1 1 Galactoside-binding lectin RRM_1 PF00076.22 OQS05773.1 - 3.9e-09 36.2 0.2 1.1e-08 34.8 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CCDC92 PF14916.6 OQS05773.1 - 0.16 11.7 3.4 0.31 10.8 3.4 1.4 1 0 0 1 1 1 0 Coiled-coil domain of unknown function RNA_bind PF08675.11 OQS05773.1 - 0.18 11.8 0.0 0.49 10.5 0.0 1.6 1 0 0 1 1 1 0 RNA binding domain zf-rbx1 PF12678.7 OQS05774.1 - 1.2e-25 89.5 12.9 1.7e-25 89.1 12.9 1.2 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 OQS05774.1 - 3e-18 65.7 9.9 3.6e-18 65.4 9.9 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.6 OQS05774.1 - 1e-06 29.0 14.6 4.5e-05 23.7 14.6 2.3 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 OQS05774.1 - 5e-05 23.1 3.3 5e-05 23.1 3.3 2.3 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 OQS05774.1 - 0.00071 19.4 11.9 0.013 15.3 11.9 2.5 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 OQS05774.1 - 0.066 13.1 11.0 0.27 11.1 4.7 2.6 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.8 OQS05774.1 - 0.11 12.7 8.6 1.2 9.4 9.1 2.0 1 1 1 2 2 2 0 FANCL C-terminal domain zf-RING_11 PF17123.5 OQS05774.1 - 0.13 12.1 15.6 0.13 12.0 8.6 2.5 1 1 1 2 2 2 0 RING-like zinc finger Zn_ribbon_17 PF17120.5 OQS05774.1 - 0.21 11.2 15.4 0.052 13.2 5.1 2.3 1 1 1 2 2 2 0 Zinc-ribbon, C4HC2 type zf-RING_UBOX PF13445.6 OQS05774.1 - 0.25 11.4 7.8 0.98 9.5 7.8 2.0 1 1 0 1 1 1 0 RING-type zinc-finger zf-RING_5 PF14634.6 OQS05774.1 - 5.9 6.9 12.8 49 4.0 12.9 2.5 1 1 1 2 2 2 0 zinc-RING finger domain zf-C3HC4_4 PF15227.6 OQS05774.1 - 8.7 6.6 9.7 0.61 10.3 0.7 2.5 2 1 0 2 2 2 0 zinc finger of C3HC4-type, RING FOP_dimer PF09398.10 OQS05775.1 - 1.4e-12 47.7 0.1 2.2e-12 47.1 0.1 1.3 1 0 0 1 1 1 1 FOP N terminal dimerisation domain LisH_2 PF16045.5 OQS05775.1 - 3.8e-10 38.6 0.0 5.5e-10 38.1 0.0 1.3 1 0 0 1 1 1 1 LisH LisH PF08513.11 OQS05775.1 - 0.023 14.7 0.1 0.046 13.7 0.1 1.5 1 0 0 1 1 1 0 LisH Asp_protease PF09668.10 OQS05776.1 - 2.3e-57 192.2 0.1 4e-57 191.4 0.1 1.4 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 OQS05776.1 - 5e-22 78.3 0.2 1.7e-21 76.6 0.0 2.0 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 OQS05776.1 - 5.3e-11 43.0 0.2 3.8e-10 40.3 0.0 2.2 2 0 0 2 2 2 1 Aspartyl protease UBA PF00627.31 OQS05776.1 - 2.1e-09 37.1 0.0 3.9e-09 36.2 0.0 1.5 1 0 0 1 1 1 1 UBA/TS-N domain ubiquitin PF00240.23 OQS05776.1 - 1.5e-08 34.3 0.0 3.2e-08 33.2 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family RVP_2 PF08284.11 OQS05776.1 - 0.00011 22.0 0.0 0.00031 20.5 0.0 1.7 1 1 0 1 1 1 1 Retroviral aspartyl protease Rad60-SLD PF11976.8 OQS05776.1 - 0.00033 20.4 0.1 0.00072 19.3 0.1 1.6 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like UBA_4 PF14555.6 OQS05776.1 - 0.00063 19.5 0.0 0.0013 18.5 0.0 1.5 1 0 0 1 1 1 1 UBA-like domain DEC-1_N PF04625.13 OQS05776.1 - 0.0087 15.1 16.5 0.19 10.7 4.1 2.1 2 0 0 2 2 2 2 DEC-1 protein, N-terminal region RVP PF00077.20 OQS05776.1 - 0.016 15.5 0.1 0.065 13.5 0.0 2.2 1 1 0 1 1 1 0 Retroviral aspartyl protease HTH_8 PF02954.19 OQS05776.1 - 0.049 13.4 0.1 0.16 11.8 0.0 1.9 2 0 0 2 2 2 0 Bacterial regulatory protein, Fis family WD40 PF00400.32 OQS05778.1 - 5.2e-26 90.4 9.3 2.2e-06 28.3 0.7 5.8 6 0 0 6 6 6 5 WD domain, G-beta repeat LisH_TPL PF17814.1 OQS05778.1 - 1.3e-15 56.7 1.5 2.3e-15 55.9 1.5 1.4 1 0 0 1 1 1 1 LisH-like dimerisation domain ANAPC4_WD40 PF12894.7 OQS05778.1 - 8.4e-13 48.4 0.0 8.1e-06 26.0 0.0 5.2 1 1 3 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 OQS05778.1 - 2.4e-12 46.5 4.7 0.00053 19.1 0.1 4.1 1 1 3 4 4 4 4 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 OQS05778.1 - 2.1e-07 30.0 0.1 0.0063 15.2 0.0 2.8 2 1 1 3 3 3 2 Nucleoporin Nup120/160 Hira PF07569.11 OQS05778.1 - 0.014 15.1 0.2 45 3.7 0.0 4.3 2 1 2 4 4 4 0 TUP1-like enhancer of split PALB2_WD40 PF16756.5 OQS05778.1 - 0.034 13.1 0.2 2.8 6.8 0.0 2.6 1 1 2 3 3 3 0 Partner and localizer of BRCA2 WD40 domain MRFAP1 PF15155.6 OQS05778.1 - 0.12 12.9 0.1 0.28 11.7 0.1 1.5 1 0 0 1 1 1 0 MORF4 family-associated protein1 GFA PF04828.14 OQS05779.1 - 0.36 11.2 5.2 7.7 6.9 0.0 2.5 3 0 0 3 3 3 0 Glutathione-dependent formaldehyde-activating enzyme Cir_N PF10197.9 OQS05780.1 - 5.6e-09 36.0 3.2 5.6e-09 36.0 3.2 3.5 3 1 0 4 4 4 1 N-terminal domain of CBF1 interacting co-repressor CIR CWC25 PF12542.8 OQS05780.1 - 2.2 9.2 0.0 2.2 9.2 0.0 4.0 3 1 1 4 4 4 0 Pre-mRNA splicing factor DUF2181 PF10223.9 OQS05783.1 - 3.1e-52 177.5 0.1 4.1e-52 177.1 0.1 1.0 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2181) PrmC_N PF17827.1 OQS05783.1 - 0.034 14.7 0.4 0.54 10.9 0.1 2.4 2 0 0 2 2 2 0 PrmC N-terminal domain His_Phos_2 PF00328.22 OQS05784.1 - 4.5e-13 49.3 0.0 4.4e-12 46.0 0.0 2.1 2 1 0 2 2 2 1 Histidine phosphatase superfamily (branch 2) Ank_2 PF12796.7 OQS05785.1 - 1.3e-27 96.1 25.3 6.4e-08 33.1 0.1 5.2 1 1 6 7 7 7 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQS05785.1 - 5.2e-26 90.7 22.1 2.8e-05 24.6 0.3 7.4 5 2 4 9 9 9 7 Ankyrin repeats (many copies) Ank_5 PF13857.6 OQS05785.1 - 2.3e-21 75.6 22.8 0.021 15.1 0.0 10.2 3 2 6 10 10 10 8 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQS05785.1 - 1.7e-11 43.2 16.1 2.1 9.2 0.0 10.1 9 2 2 11 11 11 3 Ankyrin repeat DUF5049 PF16468.5 OQS05785.1 - 0.00048 20.0 7.1 5.7 6.9 0.0 6.8 5 3 4 9 9 9 1 Domain of unknown function (DUF5049) DUF3322 PF11795.8 OQS05785.1 - 0.0063 16.5 0.1 34 4.4 0.0 4.2 3 1 2 5 5 5 0 Uncharacterized protein conserved in bacteria N-term (DUF3322) Ank PF00023.30 OQS05785.1 - 0.062 13.8 14.0 14 6.3 0.1 7.4 5 2 0 6 6 6 0 Ankyrin repeat 2CSK_N PF08521.10 OQS05785.1 - 0.1 12.7 0.0 0.2 11.8 0.0 1.4 1 0 0 1 1 1 0 Two-component sensor kinase N-terminal ABC_tran PF00005.27 OQS05786.1 - 1.8e-27 96.5 0.0 6e-27 94.8 0.0 1.9 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 OQS05786.1 - 1.1e-08 34.8 0.2 0.00087 18.8 0.1 2.4 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 OQS05786.1 - 0.00017 21.9 0.2 0.0026 18.0 0.1 2.8 2 1 0 2 2 1 1 AAA domain AAA_29 PF13555.6 OQS05786.1 - 0.0003 20.4 0.1 0.0013 18.4 0.0 2.1 2 0 0 2 2 1 1 P-loop containing region of AAA domain ABC_ATPase PF09818.9 OQS05786.1 - 0.00032 19.6 0.0 0.0079 15.0 0.1 2.5 2 0 0 2 2 2 1 Predicted ATPase of the ABC class Peptidase_C92 PF05708.12 OQS05786.1 - 0.00043 20.4 0.0 0.001 19.2 0.0 1.7 1 0 0 1 1 1 1 Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family RsgA_GTPase PF03193.16 OQS05786.1 - 0.00054 19.9 0.0 0.0015 18.5 0.0 1.7 1 0 0 1 1 1 1 RsgA GTPase AAA PF00004.29 OQS05786.1 - 0.00061 20.2 0.1 0.0082 16.6 0.0 2.8 2 1 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_23 PF13476.6 OQS05786.1 - 0.001 19.7 0.0 0.0038 17.7 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 OQS05786.1 - 0.0024 18.3 0.0 0.008 16.6 0.0 2.0 1 0 0 1 1 1 1 AAA ATPase domain RE_Eco29kI PF09517.10 OQS05786.1 - 0.0052 16.4 0.1 0.18 11.4 0.0 2.3 2 0 0 2 2 2 1 Eco29kI restriction endonuclease AAA_30 PF13604.6 OQS05786.1 - 0.0056 16.4 0.0 0.023 14.4 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_21 PF13304.6 OQS05786.1 - 0.0077 16.1 0.0 0.41 10.4 0.0 2.3 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_5 PF07728.14 OQS05786.1 - 0.013 15.5 0.6 1.2 9.2 0.0 4.0 5 0 0 5 5 4 0 AAA domain (dynein-related subfamily) MMR_HSR1 PF01926.23 OQS05786.1 - 0.016 15.3 0.0 0.045 13.8 0.0 1.8 1 0 0 1 1 1 0 50S ribosome-binding GTPase NACHT PF05729.12 OQS05786.1 - 0.029 14.3 0.0 0.11 12.4 0.0 2.1 2 0 0 2 2 1 0 NACHT domain Mg_chelatase PF01078.21 OQS05786.1 - 0.031 13.7 0.0 0.26 10.6 0.0 2.2 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_7 PF12775.7 OQS05786.1 - 0.031 13.8 0.0 0.25 10.8 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region IstB_IS21 PF01695.17 OQS05786.1 - 0.037 13.8 0.1 0.29 10.8 0.0 2.2 2 0 0 2 2 2 0 IstB-like ATP binding protein Dynamin_N PF00350.23 OQS05786.1 - 0.087 12.9 0.0 0.24 11.4 0.0 1.8 1 0 0 1 1 1 0 Dynamin family AAA_15 PF13175.6 OQS05786.1 - 0.14 11.9 0.0 0.34 10.6 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain Vps36_ESCRT-II PF11605.8 OQS05787.1 - 0.0082 16.3 0.0 0.015 15.5 0.0 1.4 1 0 0 1 1 1 1 Vacuolar protein sorting protein 36 Vps36 GRAM PF02893.20 OQS05787.1 - 0.036 13.9 0.0 0.059 13.2 0.0 1.4 1 0 0 1 1 1 0 GRAM domain AAA_5 PF07728.14 OQS05788.1 - 0.11 12.5 0.2 0.37 10.8 0.3 2.0 1 1 1 2 2 2 0 AAA domain (dynein-related subfamily) DUF3381 PF11861.8 OQS05788.1 - 5.6 6.7 17.9 0.17 11.7 10.8 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3381) 2OG-FeII_Oxy_2 PF13532.6 OQS05789.1 - 5e-14 52.9 0.8 1.1e-12 48.6 0.8 2.2 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily zf-GRF PF06839.12 OQS05789.1 - 6.1e-09 35.8 0.2 1.1e-08 35.0 0.2 1.4 1 0 0 1 1 1 1 GRF zinc finger CUE PF02845.16 OQS05789.1 - 3.1e-06 26.8 0.1 6.7e-06 25.7 0.1 1.6 1 0 0 1 1 1 1 CUE domain PALP PF00291.25 OQS05790.1 - 5.2e-77 259.1 0.4 6.2e-77 258.9 0.4 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme YjeF_N PF03853.15 OQS05790.1 - 0.07 13.0 0.1 9 6.1 0.0 3.3 2 1 1 4 4 4 0 YjeF-related protein N-terminus Acetyltransf_10 PF13673.7 OQS05791.1 - 4.2e-30 104.3 0.1 9.3e-14 51.5 0.0 2.4 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 OQS05791.1 - 1.1e-23 83.7 0.3 4e-11 43.2 0.0 2.5 2 0 0 2 2 2 2 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 OQS05791.1 - 4e-21 75.2 0.1 1e-09 38.6 0.0 2.6 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain FR47 PF08445.10 OQS05791.1 - 2.1e-12 46.8 0.0 3.3e-05 23.8 0.0 2.9 2 0 0 2 2 2 2 FR47-like protein Acetyltransf_CG PF14542.6 OQS05791.1 - 0.004 17.3 0.0 4.3 7.6 0.0 2.6 2 0 0 2 2 2 2 GCN5-related N-acetyl-transferase MTES_1575 PF18741.1 OQS05791.1 - 0.048 13.8 0.0 0.15 12.2 0.0 1.8 1 0 0 1 1 1 0 REase_MTES_1575 DUF4796 PF16044.5 OQS05791.1 - 0.064 12.8 0.0 0.7 9.5 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4796) CPT_N PF16484.5 OQS05791.1 - 0.12 12.4 0.5 5.6 7.0 0.0 3.3 3 0 0 3 3 3 0 Carnitine O-palmitoyltransferase N-terminus FIN1 PF17300.2 OQS05792.1 - 0.076 12.5 5.9 0.29 10.6 4.1 2.2 1 1 0 1 1 1 0 Filaments in between nuclei protein-1 DivIC PF04977.15 OQS05792.1 - 0.53 10.1 7.7 0.95 9.3 7.7 1.4 1 0 0 1 1 1 0 Septum formation initiator RRM_1 PF00076.22 OQS05793.1 - 3.1e-76 251.2 7.6 5.4e-20 71.0 0.0 5.5 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 OQS05793.1 - 3.6e-07 29.8 0.0 0.16 11.6 0.0 4.5 4 0 0 4 4 4 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PDZ PF00595.24 OQS05793.1 - 1.6e-06 28.4 0.0 0.0084 16.4 0.0 3.6 3 0 0 3 3 3 2 PDZ domain RRM_occluded PF16842.5 OQS05793.1 - 4.1e-06 26.6 0.3 0.19 11.6 0.0 4.6 6 0 0 6 6 6 1 Occluded RNA-recognition motif PDZ_6 PF17820.1 OQS05793.1 - 5.6e-06 26.1 0.0 0.26 11.1 0.0 3.6 3 0 0 3 3 3 2 PDZ domain PDZ_2 PF13180.6 OQS05793.1 - 0.0044 17.3 0.0 0.71 10.2 0.0 3.9 4 0 0 4 4 4 1 PDZ domain RRM_7 PF16367.5 OQS05793.1 - 0.038 14.1 0.1 61 3.8 0.0 4.5 5 0 0 5 5 5 0 RNA recognition motif PolyA_pol PF01743.20 OQS05793.1 - 0.05 14.0 0.3 18 5.7 0.0 3.2 2 0 0 2 2 2 0 Poly A polymerase head domain SNF2_N PF00176.23 OQS05794.1 - 9.3e-65 218.6 0.1 2.6e-64 217.2 0.1 1.6 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 OQS05794.1 - 1.8e-21 76.6 0.8 2.9e-20 72.7 0.0 3.1 4 0 0 4 4 4 1 Helicase conserved C-terminal domain HDA2-3 PF11496.8 OQS05794.1 - 7.2e-13 48.3 0.2 2.5e-12 46.6 0.2 1.8 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 ResIII PF04851.15 OQS05794.1 - 1.5e-11 44.6 0.0 8.1e-11 42.2 0.0 2.2 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit DEAD PF00270.29 OQS05794.1 - 0.00017 21.4 0.0 0.00037 20.3 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_34 PF13872.6 OQS05794.1 - 0.034 13.1 0.1 0.16 10.8 0.0 2.2 2 1 0 2 2 2 0 P-loop containing NTP hydrolase pore-1 Pkinase_Tyr PF07714.17 OQS05795.1 - 7.7e-55 186.0 0.0 1.2e-54 185.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OQS05795.1 - 1.5e-48 165.5 0.0 3e-48 164.5 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Actin PF00022.19 OQS05795.1 - 2.6e-30 105.3 0.0 2.8e-18 65.7 0.0 2.4 1 1 1 2 2 2 2 Actin Cofilin_ADF PF00241.20 OQS05795.1 - 9e-07 28.7 0.0 0.00019 21.2 0.0 2.8 2 0 0 2 2 2 1 Cofilin/tropomyosin-type actin-binding protein DUF2807 PF10988.8 OQS05795.1 - 1.9e-06 27.8 8.5 4.4e-06 26.6 6.6 2.5 2 1 0 2 2 2 1 Putative auto-transporter adhesin, head GIN domain Kinase-like PF14531.6 OQS05795.1 - 0.0015 17.9 0.0 0.0026 17.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 OQS05795.1 - 0.004 17.1 0.1 0.0078 16.2 0.1 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 OQS05795.1 - 0.011 14.5 0.0 0.022 13.5 0.0 1.4 1 0 0 1 1 1 0 Fungal protein kinase ubiquitin PF00240.23 OQS05795.1 - 0.063 13.0 0.0 0.22 11.3 0.0 1.9 1 0 0 1 1 1 0 Ubiquitin family Ubiquitin_2 PF14560.6 OQS05795.1 - 0.071 13.6 0.1 0.26 11.7 0.0 2.1 2 0 0 2 2 2 0 Ubiquitin-like domain Peptidase_C1 PF00112.23 OQS05797.1 - 7.1e-52 176.6 0.7 9.1e-52 176.3 0.7 1.1 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.15 OQS05797.1 - 1.3e-06 27.5 0.1 0.00045 19.1 0.1 2.1 2 0 0 2 2 2 2 Peptidase C1-like family adh_short_C2 PF13561.6 OQS05798.1 - 1.4e-48 165.5 4.8 1.8e-48 165.2 4.8 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OQS05798.1 - 1.2e-44 152.1 4.6 1.5e-44 151.8 4.6 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OQS05798.1 - 7.3e-12 45.6 3.5 9.7e-12 45.2 3.5 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 OQS05798.1 - 0.00057 19.4 1.0 0.0015 18.1 0.5 1.8 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 OQS05798.1 - 0.0025 17.0 1.0 0.0034 16.6 1.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 OQS05798.1 - 0.063 12.4 0.2 0.095 11.8 0.2 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain Methyltransf_25 PF13649.6 OQS05798.1 - 0.081 13.6 0.1 0.18 12.5 0.1 1.6 1 0 0 1 1 1 0 Methyltransferase domain DUF4539 PF15072.6 OQS05799.1 - 1.7e-14 53.6 0.0 3.1e-14 52.8 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4539) PEPCK_ATP PF01293.20 OQS05800.1 - 1.8e-213 709.4 0.0 2.1e-213 709.2 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase Malate_synthase PF01274.22 OQS05801.1 - 2.8e-88 296.5 0.0 6.5e-68 229.3 0.0 2.3 1 1 1 2 2 2 2 Malate synthase Sugar_tr PF00083.24 OQS05802.1 - 9.9e-114 380.7 32.0 1.1e-86 291.5 19.2 2.0 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 OQS05802.1 - 1.4e-29 103.1 38.3 3.3e-27 95.4 25.1 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily PSI PF01437.25 OQS05802.1 - 2.7e-06 27.8 7.5 2.7e-06 27.8 7.5 2.2 2 0 0 2 2 2 1 Plexin repeat DUF2826 PF11442.8 OQS05802.1 - 0.15 11.9 1.5 1.8 8.4 0.1 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2826) DNA_binding_1 PF01035.20 OQS05803.1 - 2.1e-24 85.4 0.0 3e-24 84.9 0.0 1.2 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain DSPc PF00782.20 OQS05806.1 - 5.1e-25 87.8 0.1 7.6e-25 87.3 0.1 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Trm112p PF03966.16 OQS05806.1 - 0.028 15.0 0.3 11 6.6 0.1 2.4 2 0 0 2 2 2 0 Trm112p-like protein Init_tRNA_PT PF04179.12 OQS05806.1 - 0.04 14.2 0.0 0.082 13.2 0.0 1.5 1 0 0 1 1 1 0 Rit1 DUSP-like domain Y_phosphatase PF00102.27 OQS05806.1 - 0.059 12.9 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 Protein-tyrosine phosphatase IBR PF01485.21 OQS05806.1 - 1.6 9.0 6.9 17 5.7 5.1 2.9 2 1 0 2 2 2 0 IBR domain, a half RING-finger domain GTP_EFTU PF00009.27 OQS05807.1 - 9.6e-64 214.5 0.2 1.4e-63 213.9 0.2 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 OQS05807.1 - 2.3e-28 98.4 0.0 9.6e-28 96.4 0.0 2.0 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.24 OQS05807.1 - 3.4e-21 75.1 0.0 1.3e-20 73.2 0.0 2.0 2 0 0 2 2 2 1 Elongation factor G C-terminus EFG_II PF14492.6 OQS05807.1 - 1.6e-14 53.7 0.0 3.3e-14 52.7 0.0 1.5 1 0 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.25 OQS05807.1 - 9.8e-13 48.3 0.0 3.4e-12 46.6 0.0 2.0 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 OQS05807.1 - 0.0017 18.4 0.1 0.0058 16.7 0.1 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase Corazonin PF17308.2 OQS05807.1 - 0.14 12.5 0.0 0.43 11.0 0.0 1.7 2 0 0 2 2 2 0 Pro-corazonin Baculo_11_kDa PF06143.11 OQS05808.1 - 0.23 11.1 0.0 0.41 10.3 0.0 1.3 1 0 0 1 1 1 0 Baculovirus 11 kDa family 2OG-FeII_Oxy_3 PF13640.6 OQS05809.1 - 2.3e-21 76.5 0.0 7.1e-21 74.9 0.0 1.9 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.6 OQS05809.1 - 1.1e-13 51.7 0.1 2.9e-13 50.3 0.0 1.8 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily She9_MDM33 PF05546.11 OQS05809.1 - 0.0015 18.4 4.5 0.42 10.4 2.1 2.3 2 0 0 2 2 2 2 She9 / Mdm33 family LRR_4 PF12799.7 OQS05809.1 - 0.096 13.1 0.5 2.2 8.8 0.2 2.8 1 1 1 2 2 2 0 Leucine Rich repeats (2 copies) AAA_lid_9 PF17871.1 OQS05809.1 - 0.21 11.5 2.4 0.44 10.5 2.4 1.5 1 0 0 1 1 1 0 AAA lid domain EF-hand_7 PF13499.6 OQS05810.1 - 8.9e-21 74.1 0.0 4.9e-12 46.1 0.1 2.9 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 OQS05810.1 - 1.2e-16 58.9 0.2 2.3e-05 23.6 0.2 4.5 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.6 OQS05810.1 - 1.6e-13 49.4 0.1 0.0015 18.3 0.0 4.8 4 0 0 4 4 4 3 EF-hand domain IQ PF00612.27 OQS05810.1 - 1.8e-11 42.8 55.6 0.00078 19.0 1.3 11.3 10 0 0 10 10 10 5 IQ calmodulin-binding motif EF-hand_8 PF13833.6 OQS05810.1 - 2.7e-09 36.7 0.4 0.0011 18.8 0.2 3.4 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.6 OQS05810.1 - 5.4e-06 25.7 6.4 0.00081 18.8 0.0 2.9 3 0 0 3 3 3 2 EF hand zf-B_box PF00643.24 OQS05810.1 - 0.00058 19.9 18.9 0.034 14.3 3.0 3.0 2 0 0 2 2 2 2 B-box zinc finger CEBP_ZZ PF16366.5 OQS05810.1 - 0.011 15.9 17.1 0.49 10.7 7.3 3.0 2 0 0 2 2 2 0 Cytoplasmic polyadenylation element-binding protein ZZ domain IBR PF01485.21 OQS05810.1 - 2 8.7 17.4 6.2 7.1 6.7 3.0 2 0 0 2 2 2 0 IBR domain, a half RING-finger domain Peptidase_M13_N PF05649.13 OQS05811.1 - 5.3e-77 260.1 0.0 7.8e-77 259.5 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13 PF01431.21 OQS05811.1 - 2.5e-68 229.7 0.7 3.9e-68 229.1 0.7 1.3 1 0 0 1 1 1 1 Peptidase family M13 Ank_5 PF13857.6 OQS05812.1 - 1.8e-31 107.8 8.1 6e-09 36.0 0.2 4.3 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank_4 PF13637.6 OQS05812.1 - 6.4e-31 106.3 2.8 2.1e-09 37.7 0.1 4.3 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 OQS05812.1 - 4.2e-30 104.2 7.1 8.2e-13 48.8 0.4 3.5 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.30 OQS05812.1 - 6e-28 96.0 10.1 4.5e-05 23.7 0.6 5.7 6 0 0 6 6 6 5 Ankyrin repeat Ank_3 PF13606.6 OQS05812.1 - 4.6e-26 88.0 3.9 0.00021 21.4 0.0 5.4 5 0 0 5 5 5 5 Ankyrin repeat WD40 PF00400.32 OQS05813.1 - 1.7e-47 158.4 30.3 4.2e-09 36.9 0.4 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OQS05813.1 - 3.3e-20 72.2 5.1 0.0003 21.0 0.1 5.8 1 1 5 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 OQS05813.1 - 8.9e-08 31.5 5.7 0.022 13.7 0.0 4.3 1 1 2 4 4 4 3 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 OQS05813.1 - 1.1e-06 28.7 4.0 0.37 10.6 0.1 4.2 2 2 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A IKI3 PF04762.12 OQS05813.1 - 3e-05 22.3 8.6 3.6e-05 22.0 2.2 2.7 1 1 2 3 3 3 2 IKI3 family PD40 PF07676.12 OQS05813.1 - 0.00031 20.6 2.9 8.6 6.4 0.1 4.2 4 0 0 4 4 4 2 WD40-like Beta Propeller Repeat nos_propeller PF18764.1 OQS05813.1 - 0.0061 16.5 0.0 2.2 8.2 0.0 3.1 3 0 0 3 3 3 1 Nitrous oxide reductase propeller repeat Coatomer_WDAD PF04053.14 OQS05813.1 - 0.016 14.3 1.7 1.5 7.7 0.1 3.4 2 2 3 5 5 5 0 Coatomer WD associated region BBS2_Mid PF14783.6 OQS05813.1 - 0.031 14.3 0.1 6.8 6.8 0.0 3.3 2 1 2 4 4 4 0 Ciliary BBSome complex subunit 2, middle region WD40_like PF17005.5 OQS05813.1 - 0.21 10.9 0.0 7 5.9 0.0 2.4 2 0 0 2 2 2 0 WD40-like domain DPPIV_N PF00930.21 OQS05813.1 - 0.39 9.4 6.9 0.92 8.2 0.1 3.4 3 1 0 4 4 4 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region DUF2387 PF09526.10 OQS05813.1 - 6.4 7.0 6.3 1.7 8.8 0.1 3.2 5 0 0 5 5 5 0 Probable metal-binding protein (DUF2387) MORN PF02493.20 OQS05814.1 - 8.5e-12 44.2 16.8 7.9e-07 28.6 1.4 4.8 4 0 0 4 4 4 4 MORN repeat 2OG-FeII_Oxy_3 PF13640.6 OQS05814.1 - 8.4e-08 33.0 0.0 0.00096 20.0 0.0 2.6 2 0 0 2 2 2 2 2OG-Fe(II) oxygenase superfamily C_Hendra PF16821.5 OQS05814.1 - 0.021 14.7 2.8 0.049 13.5 2.8 1.6 1 0 0 1 1 1 0 C protein from hendra and measles viruses Cuticle_1 PF08140.11 OQS05814.1 - 0.12 12.4 0.1 0.4 10.8 0.0 1.9 2 0 0 2 2 2 0 Crustacean cuticle protein repeat DUF4407 PF14362.6 OQS05814.1 - 0.48 9.7 7.6 0.71 9.2 7.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Peptidase_M13_N PF05649.13 OQS05816.1 - 1.8e-72 245.1 1.5 2.5e-72 244.7 1.5 1.2 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13 PF01431.21 OQS05816.1 - 3.3e-70 235.9 1.3 1.4e-69 233.8 0.1 2.1 2 0 0 2 2 2 1 Peptidase family M13 PA PF02225.22 OQS05816.1 - 0.04 13.9 0.0 0.11 12.5 0.0 1.8 1 0 0 1 1 1 0 PA domain Ank_4 PF13637.6 OQS05817.1 - 1.1e-29 102.4 12.8 1.6e-07 31.7 1.1 6.2 4 2 2 6 6 6 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 OQS05817.1 - 1.5e-22 79.3 11.9 3.2e-06 27.3 0.1 5.4 2 1 3 5 5 5 5 Ankyrin repeats (many copies) Ank_2 PF12796.7 OQS05817.1 - 7e-22 77.8 16.1 1.8e-11 44.5 1.4 4.2 1 1 4 5 5 5 4 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OQS05817.1 - 2e-20 70.7 10.7 0.0022 18.3 0.0 7.5 7 1 1 8 8 8 6 Ankyrin repeat Ank PF00023.30 OQS05817.1 - 1.7e-09 37.7 15.5 0.12 12.9 0.7 5.9 5 1 1 6 6 6 4 Ankyrin repeat DDE_3 PF13358.6 OQS05818.1 - 8.5e-22 77.5 0.0 1e-21 77.2 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease T_cell_tran_alt PF15128.6 OQS05819.1 - 0.068 13.0 0.0 0.072 12.9 0.0 1.2 1 0 0 1 1 1 0 T-cell leukemia translocation-altered AI-2E_transport PF01594.16 OQS05820.1 - 3.6e-10 39.5 22.5 3.6e-10 39.5 22.5 3.1 3 0 0 3 3 3 2 AI-2E family transporter FAD-oxidase_C PF02913.19 OQS05821.1 - 1.6e-58 198.3 0.1 3e-58 197.4 0.0 1.5 2 0 0 2 2 2 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 OQS05821.1 - 3.1e-39 133.9 0.4 5.6e-39 133.0 0.4 1.4 1 0 0 1 1 1 1 FAD binding domain LRAT PF04970.13 OQS05822.1 - 9.3e-08 32.4 0.2 6.1e-07 29.8 0.2 2.4 1 1 0 1 1 1 1 Lecithin retinol acyltransferase LMBR1 PF04791.16 OQS05823.1 - 9.8e-57 193.0 13.0 5.4e-56 190.6 13.0 1.8 1 1 0 1 1 1 1 LMBR1-like membrane protein RasGAP_C PF03836.15 OQS05823.1 - 6e-05 23.2 0.3 0.13 12.4 0.1 2.3 1 1 1 2 2 2 2 RasGAP C-terminus LCIB_C_CA PF18599.1 OQS05824.1 - 0.086 12.1 4.6 4.1 6.6 1.9 2.7 3 0 0 3 3 3 0 Limiting CO2-inducible proteins B/C beta carbonyic anhydrases DUF3886 PF13025.6 OQS05824.1 - 0.36 11.0 4.7 1.7 8.9 4.7 2.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3886) Dynactin_p22 PF07426.11 OQS05824.1 - 2.1 8.2 9.6 0.11 12.3 0.4 2.9 2 1 1 3 3 3 0 Dynactin subunit p22 Pantoate_ligase PF02569.15 OQS05825.1 - 1.7e-97 325.8 0.0 1.9e-97 325.6 0.0 1.0 1 0 0 1 1 1 1 Pantoate-beta-alanine ligase ISAV_HA PF06215.11 OQS05825.1 - 0.045 12.9 0.0 0.094 11.8 0.0 1.5 1 1 0 1 1 1 0 Infectious salmon anaemia virus haemagglutinin DUF3152 PF11350.8 OQS05825.1 - 0.069 12.8 0.1 0.13 12.0 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3152) P21-Arc PF04062.14 OQS05826.1 - 5e-67 225.3 0.0 5.5e-67 225.1 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex ARPC3 (21 kDa) subunit 5_nucleotid PF05761.14 OQS05827.1 - 5e-33 114.7 0.1 8.1e-32 110.7 0.1 2.1 1 1 0 1 1 1 1 5' nucleotidase family SPC22 PF04573.12 OQS05828.1 - 8.6e-55 184.8 1.2 9.7e-55 184.7 1.2 1.0 1 0 0 1 1 1 1 Signal peptidase subunit Glyco_hydro_18 PF00704.28 OQS05829.1 - 1.5e-10 41.3 0.6 7.8e-10 39.0 0.1 2.0 2 0 0 2 2 2 1 Glycosyl hydrolases family 18 Y_phosphatase2 PF03162.13 OQS05830.1 - 3.5e-56 189.3 0.0 4.1e-56 189.1 0.0 1.0 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.6 OQS05830.1 - 5.7e-07 29.7 0.0 8.6e-07 29.2 0.0 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 OQS05830.1 - 0.00049 19.7 0.0 0.00062 19.4 0.0 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.20 OQS05830.1 - 0.0026 17.5 0.0 0.0029 17.4 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Carn_acyltransf PF00755.20 OQS05831.1 - 4.5e-180 600.2 0.0 5.5e-180 599.9 0.0 1.1 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase Amidohydro_1 PF01979.20 OQS05831.1 - 1.2e-62 212.3 0.0 1.7e-62 211.7 0.0 1.3 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 OQS05831.1 - 4.7e-12 46.1 0.0 2.5e-07 30.5 0.0 2.4 2 0 0 2 2 2 2 Amidohydrolase family Metallophos PF00149.28 OQS05832.1 - 2.8e-07 31.2 0.6 1.2e-06 29.2 0.6 2.2 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase SpoIIIAH PF12685.7 OQS05832.1 - 0.0077 16.1 0.0 0.012 15.5 0.0 1.3 1 0 0 1 1 1 1 SpoIIIAH-like protein DUF2749 PF10907.8 OQS05832.1 - 0.18 12.0 1.3 0.54 10.5 1.3 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2749) PAM2 PF07145.15 OQS05833.1 - 0.0006 19.3 0.4 0.0017 17.9 0.4 1.8 1 0 0 1 1 1 1 Ataxin-2 C-terminal region G6PD_N PF00479.22 OQS05833.1 - 0.069 13.8 0.0 0.084 13.5 0.0 1.1 1 0 0 1 1 1 0 Glucose-6-phosphate dehydrogenase, NAD binding domain Mo25 PF08569.11 OQS05834.1 - 0.0097 15.3 0.0 0.012 15.0 0.0 1.2 1 0 0 1 1 1 1 Mo25-like PAM2 PF07145.15 OQS05835.1 - 1.4e-05 24.5 0.1 3e-05 23.4 0.1 1.6 1 0 0 1 1 1 1 Ataxin-2 C-terminal region Glyco_hydro_6 PF01341.17 OQS05837.1 - 4.8e-49 167.7 0.2 8.4e-49 166.9 0.2 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 6 FAM165 PF14981.6 OQS05837.1 - 0.014 15.2 0.1 0.029 14.2 0.1 1.5 1 0 0 1 1 1 0 FAM165 family TMEMspv1-c74-12 PF11044.8 OQS05837.1 - 0.093 12.7 0.2 0.15 12.1 0.2 1.3 1 0 0 1 1 1 0 Plectrovirus spv1-c74 ORF 12 transmembrane protein PilJ PF13675.6 OQS05838.1 - 0.0096 15.9 0.4 0.011 15.8 0.4 1.1 1 0 0 1 1 1 1 Type IV pili methyl-accepting chemotaxis transducer N-term HXXSHH PF07586.11 OQS05838.1 - 0.013 15.1 1.7 0.015 14.9 1.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1552) HalX PF08663.10 OQS05838.1 - 0.019 15.3 1.4 0.033 14.5 1.4 1.3 1 0 0 1 1 1 0 HalX domain Pkinase PF00069.25 OQS05840.1 - 1.9e-58 197.9 0.0 9.6e-58 195.6 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQS05840.1 - 3.4e-31 108.5 0.0 2.3e-28 99.2 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 OQS05840.1 - 1.1e-05 24.5 1.4 2.1e-05 23.6 1.4 1.5 1 1 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 OQS05840.1 - 7.3e-05 22.2 0.3 0.00012 21.5 0.3 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.9 OQS05840.1 - 0.00046 19.8 0.7 0.00068 19.2 0.7 1.2 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL APH PF01636.23 OQS05840.1 - 0.014 15.3 0.0 0.024 14.6 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family FTA2 PF13095.6 OQS05840.1 - 0.022 14.4 0.9 0.37 10.4 0.0 2.1 1 1 1 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Kinase-like PF14531.6 OQS05840.1 - 0.028 13.7 0.0 0.044 13.1 0.0 1.4 1 1 0 1 1 1 0 Kinase-like Brix PF04427.18 OQS05841.1 - 1.3e-38 133.1 0.0 1.7e-38 132.7 0.0 1.2 1 0 0 1 1 1 1 Brix domain Pkinase PF00069.25 OQS05842.1 - 5.1e-11 42.4 0.0 5.9e-11 42.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQS05842.1 - 4.6e-08 32.7 0.0 5.2e-08 32.5 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Methyltransf_11 PF08241.12 OQS05843.1 - 6.9e-11 42.6 0.0 1.3e-10 41.7 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OQS05843.1 - 1.3e-10 41.3 0.0 1.7e-10 40.9 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OQS05843.1 - 6.5e-10 39.6 0.0 1.3e-09 38.6 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OQS05843.1 - 3.5e-05 24.5 0.0 7.6e-05 23.4 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain MetW PF07021.12 OQS05843.1 - 0.024 14.2 0.0 0.051 13.2 0.0 1.5 1 1 0 1 1 1 0 Methionine biosynthesis protein MetW IGPS PF00218.21 OQS05844.1 - 1e-75 254.2 1.2 9.9e-75 251.0 0.5 2.3 2 0 0 2 2 2 1 Indole-3-glycerol phosphate synthase PRAI PF00697.22 OQS05844.1 - 3e-45 154.4 0.1 1.2e-40 139.4 0.0 2.2 1 1 0 2 2 2 2 N-(5'phosphoribosyl)anthranilate (PRA) isomerase DUF2859 PF11072.8 OQS05844.1 - 0.018 14.8 0.1 0.042 13.6 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2859) DUF1611_N PF17396.2 OQS05844.1 - 0.072 13.3 0.0 0.56 10.5 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1611_N) Rossmann-like domain CBM_1 PF00734.18 OQS05846.1 - 2e-15 56.4 11.8 3.9e-09 36.3 3.3 3.4 4 0 0 4 4 4 2 Fungal cellulose binding domain Y_phosphatase PF00102.27 OQS05847.1 - 2.5e-06 27.3 0.0 2.9e-06 27.0 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.20 OQS05847.1 - 2.5e-06 27.3 0.0 3.1e-06 27.0 0.0 1.3 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.6 OQS05847.1 - 0.094 12.8 0.0 0.13 12.4 0.0 1.3 1 0 0 1 1 1 0 Inositol hexakisphosphate Mid2 PF04478.12 OQS05847.1 - 0.13 12.1 0.0 0.19 11.5 0.0 1.2 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor WD40 PF00400.32 OQS05848.1 - 9.3e-13 48.4 13.0 9.2e-06 26.3 0.0 5.4 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OQS05848.1 - 0.029 14.7 0.4 4.1 7.8 0.0 3.3 1 1 2 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain 5-FTHF_cyc-lig PF01812.20 OQS05849.1 - 2.8e-36 125.1 0.0 4.6e-36 124.4 0.0 1.3 1 0 0 1 1 1 1 5-formyltetrahydrofolate cyclo-ligase family Na_Pi_cotrans PF02690.15 OQS05850.1 - 3.6e-31 108.1 29.9 2.8e-18 66.4 4.2 3.1 2 1 0 2 2 2 2 Na+/Pi-cotransporter TPR_12 PF13424.6 OQS05851.1 - 1.9e-21 76.2 9.1 1.3e-11 44.6 0.2 4.3 2 2 2 4 4 4 4 Tetratricopeptide repeat TPR_10 PF13374.6 OQS05851.1 - 4.9e-12 45.3 3.9 7.6e-06 25.6 0.0 4.1 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.17 OQS05851.1 - 1.5e-11 43.5 6.6 0.017 15.2 0.0 6.3 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_1 PF00515.28 OQS05851.1 - 1.6e-11 43.5 5.1 0.01 15.6 0.0 5.8 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_19 PF14559.6 OQS05851.1 - 2e-09 37.8 0.0 0.00046 20.6 0.6 3.2 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.6 OQS05851.1 - 8.9e-09 34.8 0.0 0.033 14.2 0.1 4.3 4 0 0 4 4 3 3 Tetratricopeptide repeat TPR_MalT PF17874.1 OQS05851.1 - 1e-06 28.4 0.0 1.8e-05 24.3 0.0 2.1 1 1 1 2 2 2 2 MalT-like TPR region TPR_16 PF13432.6 OQS05851.1 - 3e-06 27.8 0.0 0.11 13.1 0.4 3.7 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 OQS05851.1 - 7.6e-05 23.2 2.3 27 5.9 0.0 5.5 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_8 PF13181.6 OQS05851.1 - 0.00011 22.2 8.7 0.26 11.6 0.2 5.8 5 0 0 5 5 5 1 Tetratricopeptide repeat Mannosyl_trans3 PF11051.8 OQS05851.1 - 0.00014 21.3 0.5 0.2 11.0 0.0 2.4 2 0 0 2 2 2 2 Mannosyltransferase putative ANAPC3 PF12895.7 OQS05851.1 - 0.00072 19.7 1.3 0.89 9.8 0.3 4.6 4 1 0 4 4 4 1 Anaphase-promoting complex, cyclosome, subunit 3 DUF3856 PF12968.7 OQS05851.1 - 0.0011 19.1 0.1 0.028 14.5 0.0 2.8 2 1 0 2 2 2 1 Domain of Unknown Function (DUF3856) YqzH PF14164.6 OQS05851.1 - 0.0031 17.5 1.4 1.9 8.6 0.2 3.6 3 0 0 3 3 3 1 YqzH-like protein Glyco_transf_8 PF01501.20 OQS05851.1 - 0.0038 16.8 24.8 0.68 9.4 4.6 5.3 3 2 0 3 3 3 2 Glycosyl transferase family 8 TPR_17 PF13431.6 OQS05851.1 - 0.0059 16.9 0.2 0.45 11.0 0.0 3.7 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_6 PF13174.6 OQS05851.1 - 0.018 15.7 5.0 2.1 9.2 0.0 4.4 5 0 0 5 5 3 0 Tetratricopeptide repeat DUF4296 PF14129.6 OQS05851.1 - 0.054 14.1 0.0 7 7.3 0.0 3.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4296) TPR_11 PF13414.6 OQS05851.1 - 0.066 12.9 2.8 4.5 7.0 0.1 4.0 4 0 0 4 4 4 0 TPR repeat Antibiotic_NAT PF02522.14 OQS05851.1 - 0.096 12.5 0.0 0.23 11.2 0.0 1.6 1 0 0 1 1 1 0 Aminoglycoside 3-N-acetyltransferase MARVEL PF01284.23 OQS05852.1 - 0.04 14.0 18.7 0.056 13.5 18.7 1.2 1 0 0 1 1 1 0 Membrane-associating domain vMSA PF00695.19 OQS05852.1 - 0.12 11.4 1.4 0.12 11.4 0.1 1.6 1 1 0 1 1 1 0 Major surface antigen from hepadnavirus MARVEL PF01284.23 OQS05854.1 - 1.9e-08 34.4 12.1 2.5e-08 34.1 12.1 1.1 1 0 0 1 1 1 1 Membrane-associating domain TssN PF17555.2 OQS05854.1 - 2 7.7 4.4 3 7.2 4.4 1.2 1 0 0 1 1 1 0 Type VI secretion system, TssN ATP1G1_PLM_MAT8 PF02038.16 OQS05854.1 - 2.2 7.8 5.9 3.7 7.1 0.8 2.5 2 0 0 2 2 2 0 ATP1G1/PLM/MAT8 family PPR_2 PF13041.6 OQS05855.1 - 1.2e-07 31.8 0.1 0.034 14.3 0.0 3.7 3 1 0 3 3 3 2 PPR repeat family PPR_1 PF12854.7 OQS05855.1 - 0.0018 17.9 0.1 0.0041 16.8 0.1 1.5 1 0 0 1 1 1 1 PPR repeat PPR PF01535.20 OQS05855.1 - 0.0018 18.4 0.1 0.072 13.4 0.0 3.4 3 0 0 3 3 3 1 PPR repeat Frag1 PF10277.9 OQS05856.1 - 0.012 15.1 7.5 0.018 14.6 7.5 1.1 1 0 0 1 1 1 0 Frag1/DRAM/Sfk1 family YL1 PF05764.13 OQS05857.1 - 1.1e-23 84.6 24.1 1.1e-23 84.6 24.1 2.6 2 1 0 2 2 2 1 YL1 nuclear protein CDC45 PF02724.14 OQS05857.1 - 5.5 5.2 10.4 7.3 4.8 10.4 1.2 1 0 0 1 1 1 0 CDC45-like protein DUF2807 PF10988.8 OQS05858.1 - 0.00018 21.3 5.9 0.00032 20.6 4.7 1.9 1 1 1 2 2 2 1 Putative auto-transporter adhesin, head GIN domain DPCD PF14913.6 OQS05859.1 - 1.8e-62 210.1 0.0 2.1e-62 209.9 0.0 1.0 1 0 0 1 1 1 1 DPCD protein family Aa_trans PF01490.18 OQS05860.1 - 2e-38 132.2 19.6 3e-38 131.6 19.6 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 OQS05860.1 - 2e-05 23.8 7.8 2e-05 23.8 7.8 2.4 2 0 0 2 2 2 1 Tryptophan/tyrosine permease family IQ PF00612.27 OQS05860.1 - 0.0073 16.0 0.3 0.016 14.9 0.3 1.6 1 0 0 1 1 1 1 IQ calmodulin-binding motif UN_NPL4 PF11543.8 OQS05860.1 - 0.16 12.5 0.2 0.88 10.1 0.0 2.3 2 0 0 2 2 2 0 Nuclear pore localisation protein NPL4 DMRL_synthase PF00885.19 OQS05861.1 - 4.8e-58 195.0 0.1 6.4e-58 194.6 0.1 1.2 1 0 0 1 1 1 1 6,7-dimethyl-8-ribityllumazine synthase MatE PF01554.18 OQS05862.1 - 6.7e-52 175.4 41.9 4.2e-27 94.8 13.6 2.6 3 0 0 3 3 3 2 MatE Polysacc_synt_C PF14667.6 OQS05862.1 - 0.0038 17.3 3.8 0.0038 17.3 3.8 3.9 2 1 2 4 4 4 2 Polysaccharide biosynthesis C-terminal domain Robl_LC7 PF03259.17 OQS05863.1 - 2.7e-25 87.9 0.0 3.1e-25 87.8 0.0 1.0 1 0 0 1 1 1 1 Roadblock/LC7 domain LAMTOR5 PF16672.5 OQS05863.1 - 6.9e-05 22.7 0.0 9.7e-05 22.2 0.0 1.2 1 0 0 1 1 1 1 Ragulator complex protein LAMTOR5 OSK PF17182.4 OQS05863.1 - 0.021 14.0 0.0 0.025 13.8 0.0 1.1 1 0 0 1 1 1 0 OSK domain Mon1 PF03164.14 OQS05863.1 - 0.029 13.4 0.0 0.034 13.2 0.0 1.0 1 0 0 1 1 1 0 Trafficking protein Mon1 PQ-loop PF04193.14 OQS05864.1 - 2.8e-27 94.3 11.8 3.1e-14 52.5 2.1 3.3 3 0 0 3 3 3 2 PQ loop repeat BT1 PF03092.16 OQS05865.1 - 1.7e-10 39.8 13.2 4.8e-08 31.7 0.9 3.2 3 0 0 3 3 3 3 BT1 family ABC_transp_aux PF09822.9 OQS05865.1 - 3e-08 33.4 0.0 5.4e-08 32.6 0.0 1.4 1 0 0 1 1 1 1 ABC-type uncharacterized transport system DDOST_48kD PF03345.14 OQS05865.1 - 3.4e-05 22.9 0.0 0.0006 18.8 0.0 2.2 1 1 0 1 1 1 1 Oligosaccharyltransferase 48 kDa subunit beta MFS_1 PF07690.16 OQS05865.1 - 0.00012 21.2 29.3 0.00012 21.2 29.3 2.8 2 1 0 2 2 2 1 Major Facilitator Superfamily ThuA PF06283.11 OQS05865.1 - 0.011 16.0 0.0 0.017 15.3 0.0 1.3 1 0 0 1 1 1 0 Trehalose utilisation DUF4159 PF13709.6 OQS05865.1 - 0.063 12.7 0.0 0.12 11.8 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4159) DUF4350 PF14258.6 OQS05865.1 - 0.15 12.5 0.0 0.58 10.6 0.0 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4350) DUF2807 PF10988.8 OQS05866.1 - 0.23 11.3 8.0 0.43 10.4 7.5 1.7 1 1 0 1 1 1 0 Putative auto-transporter adhesin, head GIN domain TrmO PF01980.16 OQS05868.1 - 6.3e-41 139.3 0.0 2.4e-40 137.4 0.0 2.1 1 0 0 1 1 1 1 tRNA-methyltransferase O Ank_5 PF13857.6 OQS05868.1 - 2e-30 104.4 26.1 0.00026 21.2 0.1 12.9 3 3 10 13 13 13 9 Ankyrin repeats (many copies) Ank_2 PF12796.7 OQS05868.1 - 1.2e-28 99.5 20.4 3.3e-06 27.6 0.1 7.0 2 2 8 10 10 10 9 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQS05868.1 - 1.7e-28 98.6 20.4 1.7e-05 25.2 0.1 9.5 7 3 4 11 11 11 8 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQS05868.1 - 1.2e-09 37.6 13.8 41 5.2 0.0 13.1 12 2 2 14 14 14 0 Ankyrin repeat DUF5049 PF16468.5 OQS05868.1 - 6.4e-06 26.0 2.0 2 8.4 0.0 7.2 8 3 2 10 10 10 1 Domain of unknown function (DUF5049) Ank PF00023.30 OQS05868.1 - 0.00016 22.0 0.5 28 5.4 0.0 7.1 5 3 2 7 7 7 0 Ankyrin repeat Ras PF00071.22 OQS05869.1 - 8.6e-59 197.8 0.2 9.8e-59 197.6 0.2 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OQS05869.1 - 1.9e-36 124.9 0.2 4.6e-36 123.7 0.1 1.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OQS05869.1 - 2.1e-12 46.8 0.1 2.4e-12 46.7 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 OQS05869.1 - 5.1e-07 29.8 0.7 0.023 14.6 0.0 2.4 2 1 0 2 2 2 2 RsgA GTPase Gtr1_RagA PF04670.12 OQS05869.1 - 2.2e-06 27.2 0.0 2.7e-06 26.9 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 OQS05869.1 - 2.9e-05 24.1 0.0 4.2e-05 23.6 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 OQS05869.1 - 0.00049 19.7 0.3 0.0028 17.2 0.3 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 OQS05869.1 - 0.0011 18.5 0.1 0.0019 17.7 0.1 1.4 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit ABC_tran PF00005.27 OQS05869.1 - 0.0086 16.6 0.3 0.03 14.8 0.3 1.9 1 1 0 1 1 1 1 ABC transporter AAA_24 PF13479.6 OQS05869.1 - 0.015 15.1 0.0 0.44 10.2 0.0 2.3 2 1 0 2 2 2 0 AAA domain AAA_22 PF13401.6 OQS05869.1 - 0.03 14.6 0.1 0.36 11.1 0.1 2.4 1 1 0 1 1 1 0 AAA domain AAA_7 PF12775.7 OQS05869.1 - 0.03 13.8 0.1 0.048 13.2 0.1 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_16 PF13191.6 OQS05869.1 - 0.034 14.5 0.2 0.061 13.7 0.2 1.7 1 1 0 1 1 1 0 AAA ATPase domain TniB PF05621.11 OQS05869.1 - 0.038 13.4 0.0 0.22 10.9 0.0 2.0 2 0 0 2 2 2 0 Bacterial TniB protein DUF815 PF05673.13 OQS05869.1 - 0.039 13.1 0.1 0.26 10.4 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_5 PF07728.14 OQS05869.1 - 0.041 13.9 0.1 0.3 11.1 0.1 2.1 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA PF00004.29 OQS05869.1 - 0.063 13.7 0.1 4.4 7.7 0.1 2.8 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) MCR_beta PF02241.18 OQS05869.1 - 0.065 12.8 0.1 0.082 12.5 0.1 1.2 1 0 0 1 1 1 0 Methyl-coenzyme M reductase beta subunit, C-terminal domain Lar_N PF09861.9 OQS05869.1 - 0.075 12.2 0.0 0.12 11.5 0.0 1.5 1 1 0 1 1 1 0 Lactate racemase N-terminal domain AP_endonuc_2 PF01261.24 OQS05869.1 - 0.078 12.4 0.0 0.1 12.0 0.0 1.1 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel G-alpha PF00503.20 OQS05869.1 - 0.11 11.7 0.1 0.21 10.7 0.1 1.7 1 1 0 1 1 1 0 G-protein alpha subunit NACHT PF05729.12 OQS05869.1 - 0.17 11.8 0.0 0.62 10.0 0.0 1.8 2 0 0 2 2 2 0 NACHT domain Apyrase PF06079.11 OQS05870.1 - 1.1e-79 267.7 0.1 1.3e-79 267.5 0.1 1.0 1 0 0 1 1 1 1 Apyrase ETF PF01012.21 OQS05871.1 - 1.8e-37 129.0 10.5 2.8e-37 128.4 10.5 1.2 1 0 0 1 1 1 1 Electron transfer flavoprotein domain ETF_alpha PF00766.19 OQS05871.1 - 5e-37 125.8 0.8 5e-37 125.8 0.8 2.2 2 0 0 2 2 2 1 Electron transfer flavoprotein FAD-binding domain Arf PF00025.21 OQS05872.1 - 2.7e-53 180.0 0.0 3.3e-53 179.7 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.20 OQS05872.1 - 1.3e-10 41.0 0.0 3.1e-07 29.9 0.0 2.4 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.10 OQS05872.1 - 4.7e-10 39.2 0.0 5.7e-10 38.9 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.22 OQS05872.1 - 4.8e-08 32.8 0.0 6.4e-08 32.4 0.0 1.1 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 OQS05872.1 - 1.1e-07 31.4 0.0 1.4e-07 31.1 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Roc PF08477.13 OQS05872.1 - 1.2e-07 31.9 0.0 1.9e-07 31.3 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase cobW PF02492.19 OQS05872.1 - 0.00069 19.2 0.2 0.024 14.2 0.0 2.1 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain MMR_HSR1 PF01926.23 OQS05872.1 - 0.0039 17.3 0.0 0.0092 16.1 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 OQS05872.1 - 0.014 15.0 0.1 0.38 10.2 0.0 2.0 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_25 PF13481.6 OQS05872.1 - 0.023 14.3 0.1 0.03 13.9 0.1 1.4 1 1 0 1 1 1 0 AAA domain AAA_18 PF13238.6 OQS05872.1 - 0.12 12.9 0.0 0.18 12.3 0.0 1.5 1 1 0 1 1 1 0 AAA domain 6PF2K PF01591.18 OQS05872.1 - 0.2 11.0 0.0 0.31 10.3 0.0 1.3 1 0 0 1 1 1 0 6-phosphofructo-2-kinase Cyclin_N PF00134.23 OQS05873.1 - 2.7e-14 53.0 0.6 4.4e-14 52.3 0.6 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 OQS05873.1 - 0.0012 18.9 1.3 0.63 10.1 0.0 2.4 2 1 0 2 2 2 2 Cyclin, C-terminal domain ELMO_CED12 PF04727.13 OQS05874.1 - 2e-20 73.6 0.8 8.9e-20 71.5 0.1 2.2 2 0 0 2 2 2 1 ELMO/CED-12 family DUF3475 PF11961.8 OQS05875.1 - 0.033 14.2 0.5 0.12 12.5 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3475) CcmD PF04995.14 OQS05875.1 - 0.15 12.2 0.2 0.29 11.2 0.2 1.5 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) DUF2807 PF10988.8 OQS05876.1 - 0.094 12.5 7.9 0.24 11.2 6.4 2.3 1 1 1 2 2 2 0 Putative auto-transporter adhesin, head GIN domain DUF2807 PF10988.8 OQS05877.1 - 0.0003 20.6 7.6 0.016 15.0 7.6 2.9 1 1 0 1 1 1 1 Putative auto-transporter adhesin, head GIN domain DASH_Dad1 PF08649.10 OQS05877.1 - 0.09 13.0 0.1 0.2 11.9 0.1 1.5 1 0 0 1 1 1 0 DASH complex subunit Dad1 Mitoc_mL59 PF18126.1 OQS05878.1 - 1.7e-13 51.0 6.1 5.8e-13 49.3 6.1 1.7 1 1 0 1 1 1 1 Mitochondrial ribosomal protein mL59 MARVEL PF01284.23 OQS05879.1 - 0.00033 20.7 8.8 0.00044 20.3 8.8 1.1 1 0 0 1 1 1 1 Membrane-associating domain MgtE PF01769.16 OQS05879.1 - 0.62 10.5 4.5 17 5.8 4.6 2.2 1 1 0 1 1 1 0 Divalent cation transporter CS PF04969.16 OQS05880.1 - 0.0019 19.2 0.7 0.0033 18.4 0.3 1.6 2 0 0 2 2 2 1 CS domain LPD30 PF18850.1 OQS05880.1 - 0.0029 17.4 0.1 0.058 13.1 0.0 2.3 2 0 0 2 2 2 1 Large polyvalent protein associated domain 30 FAM176 PF14851.6 OQS05880.1 - 0.054 13.2 0.0 0.086 12.5 0.0 1.3 1 0 0 1 1 1 0 FAM176 family Pkinase PF00069.25 OQS05881.1 - 4.4e-40 137.7 0.0 6.1e-40 137.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQS05881.1 - 3.9e-36 124.7 0.0 5.8e-36 124.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Adeno_E3_CR2 PF02439.15 OQS05881.1 - 0.0013 18.4 4.8 0.003 17.3 4.8 1.5 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 Pkinase_fungal PF17667.1 OQS05881.1 - 0.0025 16.6 0.0 0.0037 16.1 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase TMEM154 PF15102.6 OQS05881.1 - 0.0099 15.8 0.1 0.026 14.4 0.1 1.6 1 1 0 1 1 1 1 TMEM154 protein family APH PF01636.23 OQS05881.1 - 0.064 13.2 0.0 0.1 12.5 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Herpes_gE PF02480.16 OQS05881.1 - 0.12 11.1 0.1 0.16 10.7 0.1 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E RIFIN PF02009.16 OQS05881.1 - 0.14 12.0 0.1 0.23 11.3 0.1 1.3 1 0 0 1 1 1 0 Rifin EphA2_TM PF14575.6 OQS05881.1 - 0.15 12.9 0.1 0.28 12.1 0.1 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain MGC-24 PF05283.11 OQS05881.1 - 0.21 12.0 1.0 0.41 11.1 0.8 1.6 1 1 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin RNA_GG_bind PF10258.9 OQS05882.1 - 1.2e-17 63.7 3.1 1.9e-17 63.1 3.1 1.4 1 0 0 1 1 1 1 PHAX RNA-binding domain EF-hand_1 PF00036.32 OQS05883.1 - 2.3e-15 54.9 2.2 0.00032 20.0 0.1 5.1 5 0 0 5 5 5 3 EF hand Ank_2 PF12796.7 OQS05883.1 - 1.4e-14 54.5 10.2 9e-07 29.4 0.4 3.9 2 1 2 5 5 5 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQS05883.1 - 7.7e-13 48.7 8.0 0.012 16.2 0.1 5.0 4 1 0 5 5 4 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 OQS05883.1 - 5.2e-12 45.8 3.0 0.0066 16.7 0.0 6.0 2 2 2 5 5 5 3 Ankyrin repeats (many copies) EF-hand_7 PF13499.6 OQS05883.1 - 7.7e-12 45.5 3.6 1.2e-08 35.3 0.2 3.1 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.6 OQS05883.1 - 3.1e-11 42.2 10.8 0.025 14.5 0.0 5.2 5 0 0 5 5 5 3 EF-hand domain Ank_3 PF13606.6 OQS05883.1 - 5.1e-09 35.6 4.1 0.59 10.9 0.0 6.7 8 0 0 8 8 7 2 Ankyrin repeat EF-hand_8 PF13833.6 OQS05883.1 - 4.2e-08 32.9 3.3 1.8e-05 24.5 0.5 3.7 3 1 1 4 4 4 2 EF-hand domain pair EF-hand_9 PF14658.6 OQS05883.1 - 4.8e-05 23.6 0.1 0.39 11.1 0.0 2.9 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 OQS05883.1 - 0.0027 17.1 1.0 0.31 10.6 0.1 2.9 2 0 0 2 2 2 1 EF hand Ank PF00023.30 OQS05883.1 - 0.0028 18.0 0.9 22 5.7 0.1 4.7 3 1 0 3 3 3 0 Ankyrin repeat Phosphodiest PF01663.22 OQS05884.1 - 6.9e-10 39.0 0.2 1e-09 38.4 0.2 1.2 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Metalloenzyme PF01676.18 OQS05884.1 - 0.00078 18.9 0.1 0.002 17.5 0.0 1.6 1 1 1 2 2 2 1 Metalloenzyme superfamily PglZ PF08665.12 OQS05884.1 - 0.016 15.3 1.4 0.42 10.7 0.0 2.6 3 0 0 3 3 3 0 PglZ domain RabGGT_insert PF07711.11 OQS05885.1 - 0.11 13.0 0.0 0.12 12.8 0.0 1.3 1 1 0 1 1 1 0 Rab geranylgeranyl transferase alpha-subunit, insert domain DivIC PF04977.15 OQS05886.1 - 4.5 7.1 13.4 0.31 10.8 4.1 3.1 2 1 1 3 3 3 0 Septum formation initiator GST_C_3 PF14497.6 OQS05887.1 - 6.6e-17 61.5 0.0 9.4e-17 61.0 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 OQS05887.1 - 1.7e-07 31.1 0.1 9e-07 28.8 0.1 2.1 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 OQS05887.1 - 7.6e-07 29.4 0.0 2.2e-06 27.9 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 OQS05887.1 - 7.9e-07 29.2 0.0 1.3e-06 28.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 OQS05887.1 - 0.0087 16.5 0.0 0.024 15.0 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain Ribosomal_S8 PF00410.19 OQS05889.1 - 0.079 12.9 0.2 0.96 9.4 0.1 2.1 1 1 1 2 2 2 0 Ribosomal protein S8 Laminin_G_3 PF13385.6 OQS05890.1 - 3.9e-18 66.0 20.3 9.9e-13 48.5 0.5 6.1 4 1 0 4 4 4 3 Concanavalin A-like lectin/glucanases superfamily CUB PF00431.20 OQS05890.1 - 8.7e-10 38.9 0.3 0.002 18.4 0.0 6.0 6 0 0 6 6 6 2 CUB domain EGF_Tenascin PF18720.1 OQS05890.1 - 0.0027 17.7 29.5 0.012 15.6 12.0 3.7 2 0 0 2 2 2 2 Tenascin EGF domain AF-4 PF05110.13 OQS05890.1 - 0.033 12.3 12.0 0.05 11.7 12.0 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Macoilin PF09726.9 OQS05890.1 - 2 6.9 5.2 3.1 6.2 5.2 1.1 1 0 0 1 1 1 0 Macoilin family I-EGF_1 PF18372.1 OQS05890.1 - 3.9 7.6 27.1 2.7 8.2 8.6 3.1 2 0 0 2 2 2 0 Integrin beta epidermal growth factor like domain 1 Squash PF00299.18 OQS05890.1 - 8.8 6.5 10.1 2.3 8.3 1.4 3.1 2 0 0 2 2 2 0 Squash family serine protease inhibitor RRM_1 PF00076.22 OQS05891.1 - 1.9e-07 30.8 0.0 0.0014 18.4 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) 2-oxoacid_dh PF00198.23 OQS05892.1 - 3.5e-78 262.3 0.6 4.4e-78 261.9 0.6 1.1 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 OQS05892.1 - 2.4e-20 72.1 2.2 4.6e-20 71.2 2.2 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme HlyD_3 PF13437.6 OQS05892.1 - 0.013 16.2 3.7 0.058 14.1 0.3 2.5 1 1 1 2 2 2 0 HlyD family secretion protein WD40 PF00400.32 OQS05893.1 - 1.2e-33 114.6 7.1 1.3e-05 25.8 0.1 7.2 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OQS05893.1 - 3e-08 33.8 0.0 0.18 12.1 0.0 4.3 4 1 1 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain ELYS-bb PF16687.5 OQS05893.1 - 0.084 11.5 0.0 0.71 8.4 0.0 2.0 2 0 0 2 2 2 0 beta-propeller of ELYS nucleoporin Mob1_phocein PF03637.17 OQS05894.1 - 2e-31 109.3 3.7 3.3e-31 108.6 3.7 1.3 1 0 0 1 1 1 1 Mob1/phocein family WD40 PF00400.32 OQS05894.1 - 9.9e-21 73.7 7.5 5e-05 24.0 0.1 6.4 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OQS05894.1 - 1.3e-12 47.8 0.0 0.052 13.9 0.0 5.2 3 2 2 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain PQQ_2 PF13360.6 OQS05894.1 - 0.0009 18.9 0.0 0.0028 17.3 0.0 1.7 1 1 0 1 1 1 1 PQQ-like domain Nup160 PF11715.8 OQS05894.1 - 0.001 17.8 0.1 0.12 10.9 0.0 2.3 2 0 0 2 2 2 2 Nucleoporin Nup120/160 Snf7 PF03357.21 OQS05895.1 - 2.8e-38 131.2 26.6 3.6e-38 130.9 26.6 1.1 1 0 0 1 1 1 1 Snf7 z-alpha PF02295.17 OQS05895.1 - 0.25 11.4 0.2 0.25 11.4 0.2 2.5 3 0 0 3 3 3 0 Adenosine deaminase z-alpha domain DUF4047 PF13256.6 OQS05895.1 - 0.57 10.4 13.7 1 9.6 2.2 2.7 1 1 2 3 3 3 0 Domain of unknown function (DUF4047) YlqD PF11068.8 OQS05895.1 - 0.97 9.8 19.6 0.49 10.8 6.8 2.2 1 1 1 2 2 2 0 YlqD protein DUF2439 PF10382.9 OQS05896.1 - 5.6e-14 52.2 0.0 1.1e-13 51.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2439) DSS1_SEM1 PF05160.13 OQS05897.1 - 8.8e-18 64.1 14.8 1e-17 63.9 14.8 1.0 1 0 0 1 1 1 1 DSS1/SEM1 family Lum_binding PF00677.17 OQS05898.1 - 2.3e-42 142.9 3.2 6.2e-21 74.2 0.1 2.6 2 0 0 2 2 2 2 Lumazine binding domain DUF21 PF01595.20 OQS05898.1 - 2.2e-25 89.4 4.0 4.2e-25 88.5 4.0 1.4 1 0 0 1 1 1 1 Cyclin M transmembrane N-terminal domain YrhC PF14143.6 OQS05898.1 - 0.47 10.6 2.1 1.5 9.0 2.1 1.8 1 0 0 1 1 1 0 YrhC-like protein His_Phos_1 PF00300.22 OQS05899.1 - 1.9e-31 109.2 0.0 2.5e-31 108.9 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Saf_2TM PF18303.1 OQS05899.1 - 0.013 15.1 0.3 0.055 13.1 0.0 2.0 2 0 0 2 2 2 0 SAVED-fused 2TM effector domain FKBP_C PF00254.28 OQS05900.1 - 7.7e-53 176.8 0.0 4.2e-33 113.5 0.0 2.3 2 0 0 2 2 2 2 FKBP-type peptidyl-prolyl cis-trans isomerase Glyco_hydro_35 PF01301.19 OQS05901.1 - 0.036 13.7 1.6 0.056 13.0 1.0 1.3 1 1 0 1 1 1 0 Glycosyl hydrolases family 35 HMGL-like PF00682.19 OQS05902.1 - 2.6e-63 214.0 0.0 3e-63 213.9 0.0 1.0 1 0 0 1 1 1 1 HMGL-like Abhydro_lipase PF04083.16 OQS05902.1 - 0.18 11.4 0.0 7 6.3 0.0 2.3 2 0 0 2 2 2 0 Partial alpha/beta-hydrolase lipase region MDD_C PF18376.1 OQS05903.1 - 4.2e-70 235.3 0.1 9.9e-70 234.1 0.1 1.7 1 0 0 1 1 1 1 Mevalonate 5-diphosphate decarboxylase C-terminal domain GHMP_kinases_N PF00288.26 OQS05903.1 - 1.3e-06 28.5 0.8 2.7e-06 27.5 0.8 1.6 1 0 0 1 1 1 1 GHMP kinases N terminal domain MEA1 PF06910.11 OQS05903.1 - 8.9e-05 23.1 5.7 0.00028 21.5 4.0 2.2 2 0 0 2 2 2 1 Male enhanced antigen 1 (MEA1) OTCace PF00185.24 OQS05905.1 - 4.8e-53 179.4 0.1 1.3e-52 178.0 0.0 1.7 2 0 0 2 2 2 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain OTCace_N PF02729.21 OQS05905.1 - 2.4e-45 154.2 0.1 3.5e-45 153.6 0.1 1.2 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain zf-CSL PF05207.13 OQS05906.1 - 1.2e-19 69.7 2.3 2.2e-19 68.9 2.3 1.5 1 0 0 1 1 1 1 CSL zinc finger DnaJ PF00226.31 OQS05906.1 - 1.1e-17 63.9 0.4 1.5e-17 63.4 0.4 1.3 1 0 0 1 1 1 1 DnaJ domain PhoLip_ATPase_C PF16212.5 OQS05907.1 - 1.6e-60 204.9 23.2 1.6e-60 204.9 23.2 2.9 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 OQS05907.1 - 2.1e-19 69.0 0.5 8.6e-19 67.0 0.6 2.0 2 0 0 2 2 2 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 OQS05907.1 - 9e-11 42.4 0.2 0.0022 18.3 0.0 3.3 3 0 0 3 3 3 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 OQS05907.1 - 7.2e-10 38.8 0.0 2.5e-09 37.1 0.0 1.9 2 0 0 2 2 2 1 Cation transport ATPase (P-type) E1-E2_ATPase PF00122.20 OQS05907.1 - 7.9e-09 35.3 0.0 1.7e-08 34.2 0.0 1.5 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase_3 PF08282.12 OQS05907.1 - 2.8e-05 24.0 0.0 6.4e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 OQS05907.1 - 0.053 13.9 0.0 4.7 7.6 0.0 2.7 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase OPA3 PF07047.12 OQS05909.1 - 2.1e-29 101.8 0.0 2.7e-29 101.5 0.0 1.2 1 0 0 1 1 1 1 Optic atrophy 3 protein (OPA3) Halogen_Hydrol PF10112.9 OQS05909.1 - 0.0044 17.1 0.3 0.0061 16.6 0.3 1.2 1 0 0 1 1 1 1 5-bromo-4-chloroindolyl phosphate hydrolysis protein LOH1CR12 PF10158.9 OQS05909.1 - 0.088 12.8 0.6 0.19 11.8 0.3 1.6 2 0 0 2 2 2 0 Tumour suppressor protein RWP-RK PF02042.15 OQS05910.1 - 4.7e-17 61.7 0.6 1.5e-16 60.1 0.1 1.9 2 0 0 2 2 2 1 RWP-RK domain DUF4708 PF15813.5 OQS05911.1 - 9.5e-07 28.2 0.1 1.5e-06 27.6 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4708) EthD PF07110.11 OQS05911.1 - 0.081 14.1 0.2 17 6.6 0.0 2.4 1 1 1 2 2 2 0 EthD domain Tcp10_C PF07202.13 OQS05912.1 - 0.003 17.5 0.8 0.1 12.5 0.0 2.7 2 1 0 2 2 2 1 T-complex protein 10 C-terminus TFIIA PF03153.13 OQS05912.1 - 0.0059 16.7 3.5 0.0059 16.7 3.5 1.6 2 0 0 2 2 2 1 Transcription factor IIA, alpha/beta subunit PPP4R2 PF09184.11 OQS05912.1 - 1.8 8.1 11.0 3.8 7.0 11.0 1.5 1 0 0 1 1 1 0 PPP4R2 Astro_capsid_p PF12226.8 OQS05912.1 - 5.7 6.0 10.2 10 5.2 10.2 1.3 1 0 0 1 1 1 0 Turkey astrovirus capsid protein HALZ PF02183.18 OQS05913.1 - 0.005 17.0 3.8 0.12 12.6 0.4 3.3 2 0 0 2 2 2 1 Homeobox associated leucine zipper GAS PF13851.6 OQS05913.1 - 0.0067 15.8 5.8 0.0067 15.8 5.8 3.7 3 1 0 3 3 3 1 Growth-arrest specific micro-tubule binding APC_N_CC PF16689.5 OQS05913.1 - 0.024 14.7 0.7 0.024 14.7 0.7 3.2 3 0 0 3 3 3 0 Coiled-coil N-terminus of APC, dimerisation domain Seadorna_VP7 PF07387.11 OQS05913.1 - 0.16 11.0 1.9 0.58 9.1 0.1 2.2 2 0 0 2 2 2 0 Seadornavirus VP7 Fez1 PF06818.15 OQS05913.1 - 0.72 10.3 39.0 2.9 8.3 9.2 3.5 1 1 2 3 3 3 0 Fez1 Terminase_6C PF17289.2 OQS05913.1 - 0.79 9.8 4.8 5 7.2 0.6 2.5 2 0 0 2 2 2 0 Terminase RNaseH-like domain LOH1CR12 PF10158.9 OQS05913.1 - 1.2 9.2 13.1 0.6 10.1 2.0 3.6 3 1 0 3 3 3 0 Tumour suppressor protein YfhD PF14151.6 OQS05913.1 - 1.7 8.8 6.5 13 6.0 1.4 2.7 2 0 0 2 2 2 0 YfhD-like protein DUF2935 PF11155.8 OQS05913.1 - 7.9 6.8 11.8 3.1 8.1 0.6 3.5 3 1 0 3 3 3 0 Domain of unknown function (DUF2935) Abhydrolase_2 PF02230.16 OQS05914.1 - 2.6e-49 167.9 0.0 3e-49 167.7 0.0 1.0 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase DLH PF01738.18 OQS05914.1 - 1.5e-07 31.2 0.0 1.9e-07 30.8 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Peptidase_S9 PF00326.21 OQS05914.1 - 5.2e-07 29.4 1.2 1.1e-05 25.1 0.1 2.4 2 1 1 3 3 3 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 OQS05914.1 - 2.9e-06 26.7 0.2 0.04 13.2 0.0 2.4 2 1 1 3 3 3 2 Serine aminopeptidase, S33 Abhydrolase_3 PF07859.13 OQS05914.1 - 9.6e-06 25.6 0.6 0.008 16.0 0.1 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold FSH1 PF03959.13 OQS05914.1 - 3e-05 23.8 0.0 6.1e-05 22.8 0.0 1.7 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Cutinase PF01083.22 OQS05914.1 - 0.0034 17.4 0.0 0.0073 16.3 0.0 1.5 2 0 0 2 2 2 1 Cutinase Abhydrolase_1 PF00561.20 OQS05914.1 - 0.026 14.2 0.1 0.087 12.4 0.1 1.9 1 1 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_8 PF06259.12 OQS05914.1 - 0.084 12.5 0.0 0.11 12.1 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase Lipase_3 PF01764.25 OQS05914.1 - 0.1 12.5 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) DUF4471 PF14740.6 OQS05915.1 - 4.9e-84 282.2 5.5 6.4e-84 281.8 5.5 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4471) DUF4470 PF14737.6 OQS05915.1 - 4.9e-21 74.7 0.7 1.1e-20 73.6 0.3 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4470) RhoGAP PF00620.27 OQS05916.1 - 4.5e-23 81.7 0.3 9.5e-23 80.7 0.1 1.6 2 0 0 2 2 2 1 RhoGAP domain WH1 PF00568.23 OQS05916.1 - 0.00056 19.8 0.2 0.001 19.0 0.2 1.4 1 0 0 1 1 1 1 WH1 domain PBD PF00786.28 OQS05916.1 - 0.00079 19.7 0.0 0.16 12.4 0.0 2.7 2 0 0 2 2 2 1 P21-Rho-binding domain Endomucin PF07010.12 OQS05916.1 - 0.08 12.9 1.7 0.13 12.2 1.7 1.4 1 0 0 1 1 1 0 Endomucin DNA_repr_REX1B PF14966.6 OQS05918.1 - 1.4e-20 73.7 3.2 1.4e-20 73.7 3.2 1.7 2 0 0 2 2 2 1 DNA repair REX1-B CDC37_C PF08564.10 OQS05918.1 - 0.039 14.1 2.2 1 9.6 0.0 3.1 3 1 1 4 4 4 0 Cdc37 C terminal domain Vac_Fusion PF02346.16 OQS05918.1 - 0.11 12.2 1.8 0.17 11.5 0.4 2.1 2 0 0 2 2 2 0 Chordopoxvirus multifunctional envelope protein A27 DUF4665 PF15679.5 OQS05918.1 - 0.32 11.7 3.1 3.8 8.2 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4665) Ctf8 PF09696.10 OQS05919.1 - 1.2e-05 25.7 0.2 0.00084 19.7 0.0 2.2 1 1 0 2 2 2 2 Ctf8 zf-C3HC4_2 PF13923.6 OQS05921.1 - 3.7e-10 39.5 8.6 3.7e-10 39.5 8.6 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 OQS05921.1 - 1e-09 38.5 8.3 1e-09 38.5 8.3 1.9 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.6 OQS05921.1 - 1.4e-09 37.6 7.8 1.4e-09 37.6 7.8 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 OQS05921.1 - 9e-09 35.1 9.0 9e-09 35.1 9.0 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OQS05921.1 - 1.3e-08 34.6 7.9 1.3e-08 34.6 7.9 1.7 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 OQS05921.1 - 1.6e-08 34.4 8.7 1.6e-08 34.4 8.7 1.7 2 0 0 2 2 1 1 RING-type zinc-finger Prok-RING_4 PF14447.6 OQS05921.1 - 4e-08 33.0 12.6 4e-07 29.8 5.0 2.4 1 1 1 2 2 2 2 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 OQS05921.1 - 6.4e-07 29.4 8.8 6.4e-07 29.4 8.8 1.7 2 0 0 2 2 1 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.7 OQS05921.1 - 0.00012 22.3 10.3 0.00048 20.3 10.3 2.0 1 1 0 1 1 1 1 RING-H2 zinc finger domain Rad50_zn_hook PF04423.14 OQS05921.1 - 0.0027 17.5 0.4 0.16 11.9 0.2 2.3 2 0 0 2 2 2 1 Rad50 zinc hook motif zf-RING_6 PF14835.6 OQS05921.1 - 0.0048 16.7 8.7 0.023 14.6 8.7 2.1 1 1 0 1 1 1 1 zf-RING of BARD1-type protein zf-RING_4 PF14570.6 OQS05921.1 - 0.0096 15.7 11.0 0.045 13.5 7.9 2.3 1 1 1 2 2 2 1 RING/Ubox like zinc-binding domain zf-Nse PF11789.8 OQS05921.1 - 0.026 14.3 5.3 0.099 12.5 4.3 2.2 1 1 1 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_10 PF16685.5 OQS05921.1 - 0.026 14.6 10.1 0.069 13.3 7.1 2.2 1 1 1 2 2 2 0 zinc RING finger of MSL2 zf-P11 PF03854.14 OQS05921.1 - 0.028 14.1 7.2 0.028 14.1 7.2 1.8 1 1 1 2 2 2 0 P-11 zinc finger zf-RING_11 PF17123.5 OQS05921.1 - 0.052 13.3 7.5 0.052 13.3 7.5 2.7 3 0 0 3 3 3 0 RING-like zinc finger zinc-ribbons_6 PF07191.12 OQS05921.1 - 0.49 10.4 9.4 13 5.9 9.4 2.2 1 1 0 1 1 1 0 zinc-ribbons FYVE PF01363.21 OQS05921.1 - 0.54 10.4 10.1 0.23 11.6 5.4 2.4 1 1 1 2 2 2 0 FYVE zinc finger Zn_Tnp_IS91 PF14319.6 OQS05921.1 - 3.5 7.7 9.5 0.57 10.3 4.8 1.9 1 1 1 2 2 2 0 Transposase zinc-binding domain Kelch_4 PF13418.6 OQS05922.1 - 4.6e-45 151.4 0.7 1e-12 47.9 0.0 6.3 3 2 2 5 5 5 5 Galactose oxidase, central domain Kelch_3 PF13415.6 OQS05922.1 - 1.6e-36 123.9 0.1 1.1e-10 41.5 0.0 6.3 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_6 PF13964.6 OQS05922.1 - 2.7e-35 119.5 0.8 7e-10 38.8 0.0 5.3 4 1 1 5 5 5 4 Kelch motif Kelch_5 PF13854.6 OQS05922.1 - 6.7e-24 83.4 2.1 5.2e-06 26.3 0.0 5.8 5 2 0 5 5 5 5 Kelch motif Kelch_2 PF07646.15 OQS05922.1 - 3.2e-19 68.1 11.6 0.0006 19.7 0.0 6.2 6 1 0 6 6 6 5 Kelch motif Kelch_1 PF01344.25 OQS05922.1 - 2.3e-18 65.5 5.1 0.00011 21.7 0.2 5.2 5 1 0 5 5 5 4 Kelch motif PEHE PF15275.6 OQS05922.1 - 0.003 18.2 2.5 0.14 12.8 0.5 2.3 2 0 0 2 2 2 1 PEHE domain CNDH2_C PF16858.5 OQS05922.1 - 0.072 13.0 10.0 0.16 11.8 3.1 2.1 2 0 0 2 2 2 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term Eapp_C PF10238.9 OQS05922.1 - 0.12 12.4 6.7 3.1 7.9 0.4 2.2 2 0 0 2 2 2 0 E2F-associated phosphoprotein EMC3_TMCO1 PF01956.16 OQS05922.1 - 1.2 8.8 4.4 2 8.2 4.4 1.3 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like Membralin PF09746.9 OQS05923.1 - 2.1e-12 46.8 16.9 6.8e-09 35.3 13.2 2.2 1 1 1 2 2 2 2 Tumour-associated protein SRP54 PF00448.22 OQS05924.1 - 2.3e-53 180.8 0.0 4.3e-53 179.9 0.0 1.5 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SRP-alpha_N PF04086.13 OQS05924.1 - 4.2e-35 122.1 10.4 9.1e-35 121.0 10.4 1.5 1 0 0 1 1 1 1 Signal recognition particle, alpha subunit, N-terminal MeaB PF03308.16 OQS05924.1 - 3e-10 39.6 0.0 7.6e-10 38.2 0.0 1.6 1 1 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB SRP54_N PF02881.19 OQS05924.1 - 2.2e-08 34.2 1.4 9.1e-08 32.2 0.1 2.7 2 1 0 2 2 2 1 SRP54-type protein, helical bundle domain AAA_16 PF13191.6 OQS05924.1 - 1e-05 26.0 0.1 0.00018 21.9 0.0 2.6 2 1 0 2 2 2 1 AAA ATPase domain CbiA PF01656.23 OQS05924.1 - 0.00016 21.7 0.0 0.0008 19.5 0.0 2.2 2 1 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_30 PF13604.6 OQS05924.1 - 0.0017 18.1 0.0 0.0049 16.6 0.0 1.8 1 0 0 1 1 1 1 AAA domain Fer4_NifH PF00142.18 OQS05924.1 - 0.002 17.6 0.0 0.0048 16.4 0.0 1.6 1 0 0 1 1 1 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family MMR_HSR1 PF01926.23 OQS05924.1 - 0.0023 18.0 0.0 0.019 15.1 0.0 2.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase NTPase_1 PF03266.15 OQS05924.1 - 0.003 17.5 4.1 0.0057 16.6 0.1 2.9 4 0 0 4 4 4 1 NTPase AAA_19 PF13245.6 OQS05924.1 - 0.0072 16.7 0.0 0.019 15.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 OQS05924.1 - 0.0092 16.3 0.1 0.058 13.7 0.0 2.3 2 0 0 2 2 2 1 AAA domain LPD14 PF18827.1 OQS05924.1 - 0.011 16.0 0.0 0.029 14.6 0.0 1.7 1 0 0 1 1 1 0 Large polyvalent protein-associated domain 14 AAA PF00004.29 OQS05924.1 - 0.014 15.8 0.3 0.086 13.3 0.0 2.4 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 OQS05924.1 - 0.028 14.1 0.1 0.32 10.7 0.0 2.6 3 0 0 3 3 3 0 AAA domain RsgA_GTPase PF03193.16 OQS05924.1 - 0.03 14.2 0.0 0.79 9.6 0.0 2.5 2 0 0 2 2 2 0 RsgA GTPase AAA_17 PF13207.6 OQS05924.1 - 0.045 14.2 0.0 0.24 11.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_31 PF13614.6 OQS05924.1 - 0.08 12.9 1.3 0.27 11.1 0.1 2.3 2 1 0 3 3 3 0 AAA domain AAA_28 PF13521.6 OQS05924.1 - 0.083 13.1 0.0 0.18 12.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain Sugar_tr PF00083.24 OQS05925.1 - 4.2e-103 345.6 29.6 4.8e-103 345.4 29.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OQS05925.1 - 4.5e-28 98.2 36.5 2.7e-20 72.6 13.6 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily adh_short PF00106.25 OQS05926.1 - 2.5e-32 111.9 1.9 2.2e-26 92.5 2.0 3.0 2 1 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 OQS05926.1 - 5.1e-19 68.8 0.3 3.4e-14 53.0 0.0 2.9 2 1 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OQS05926.1 - 8.7e-05 22.5 0.0 0.00015 21.8 0.0 1.3 1 0 0 1 1 1 1 KR domain Ank_4 PF13637.6 OQS05927.1 - 0.00054 20.5 0.2 0.0017 18.9 0.2 2.0 1 1 0 1 1 1 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 OQS05927.1 - 0.12 12.7 0.0 0.31 11.4 0.0 1.7 1 0 0 1 1 1 0 Ankyrin repeats (many copies) JmjN PF02375.17 OQS05927.1 - 0.12 12.3 0.1 0.45 10.5 0.1 2.0 2 0 0 2 2 2 0 jmjN domain Ank_3 PF13606.6 OQS05927.1 - 0.14 12.8 0.1 24 5.9 0.0 2.9 2 0 0 2 2 2 0 Ankyrin repeat Tox-PLDMTX PF15645.6 OQS05927.1 - 0.27 11.5 2.8 1 9.6 0.1 2.4 2 1 0 2 2 2 0 Dermonecrotoxin of the Papain-like fold GlcNAc PF11397.8 OQS05928.1 - 2.6e-32 112.7 2.5 1.7e-27 96.9 1.0 2.5 1 1 1 2 2 2 2 Glycosyltransferase (GlcNAc) FA_desaturase PF00487.24 OQS05929.1 - 1.4e-29 103.7 24.0 1.8e-29 103.3 24.0 1.1 1 0 0 1 1 1 1 Fatty acid desaturase NPR3 PF03666.13 OQS05931.1 - 2e-40 139.0 12.7 1.3e-20 73.6 4.0 3.8 2 1 2 4 4 4 3 Nitrogen Permease regulator of amino acid transport activity 3 NPR2 PF06218.11 OQS05931.1 - 0.022 13.5 0.1 0.047 12.5 0.1 1.5 1 0 0 1 1 1 0 Nitrogen permease regulator 2 DUF818 PF05677.12 OQS05932.1 - 6e-05 22.2 0.0 0.0001 21.4 0.0 1.4 1 0 0 1 1 1 1 Chlamydia CHLPS protein (DUF818) Abhydrolase_6 PF12697.7 OQS05932.1 - 8.3e-05 23.3 0.0 0.00021 22.0 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 OQS05932.1 - 0.00027 20.3 0.0 0.00054 19.3 0.0 1.5 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 OQS05932.1 - 0.0019 17.9 0.0 0.004 16.8 0.0 1.6 1 0 0 1 1 1 1 alpha/beta hydrolase fold tRNA_edit PF04073.15 OQS05933.1 - 8e-25 87.3 1.5 2.1e-24 85.9 1.5 1.8 1 0 0 1 1 1 1 Aminoacyl-tRNA editing domain tRNA-synt_2b PF00587.25 OQS05933.1 - 9.3e-19 68.1 0.0 2.6e-18 66.6 0.0 1.8 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) ProRS-C_1 PF09180.11 OQS05933.1 - 1.4e-18 66.8 1.0 6.3e-18 64.7 1.0 2.2 1 0 0 1 1 1 1 Prolyl-tRNA synthetase, C-terminal HGTP_anticodon PF03129.20 OQS05933.1 - 2.1e-17 63.0 0.6 2.9e-16 59.4 0.0 3.3 3 0 0 3 3 3 1 Anticodon binding domain WD40 PF00400.32 OQS05934.1 - 2.1e-12 47.3 8.0 0.0018 19.1 0.1 9.2 10 0 0 10 10 10 4 WD domain, G-beta repeat ASH PF15780.5 OQS05935.1 - 3.5e-08 33.5 12.2 0.041 14.1 0.2 8.6 11 0 0 11 11 11 3 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin DUF1573 PF07610.11 OQS05935.1 - 0.00011 22.1 2.2 1.5 8.9 0.3 5.2 5 0 0 5 5 5 2 Protein of unknown function (DUF1573) TMEM131_like PF12371.8 OQS05935.1 - 0.0044 17.2 1.3 4.8 7.5 0.1 4.4 4 0 0 4 4 4 2 Transmembrane protein 131-like FixG_C PF11614.8 OQS05935.1 - 0.94 9.7 5.0 5.3 7.3 0.3 4.6 6 0 0 6 6 6 0 IG-like fold at C-terminal of FixG, putative oxidoreductase DUF3338 PF11819.8 OQS05935.1 - 1.2 9.2 4.4 0.94 9.5 1.7 2.3 3 0 0 3 3 3 0 Domain of unknown function (DUF3338) Nore1-SARAH PF16517.5 OQS05936.1 - 0.01 15.7 3.9 0.024 14.5 1.9 2.3 2 0 0 2 2 2 0 Novel Ras effector 1 C-terminal SARAH (Sav/Rassf/Hpo) domain Isochorismatase PF00857.20 OQS05937.1 - 2.7e-52 177.5 1.3 2.6e-26 92.9 0.2 2.5 2 0 0 2 2 2 2 Isochorismatase family Peptidase_C69 PF03577.15 OQS05937.1 - 1.9e-38 132.4 1.9 4.3e-38 131.3 1.9 1.6 1 0 0 1 1 1 1 Peptidase family C69 TPR_1 PF00515.28 OQS05937.1 - 1.7e-07 30.7 0.4 0.00036 20.2 0.0 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 OQS05937.1 - 1e-05 25.2 0.2 0.0058 16.7 0.0 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.6 OQS05937.1 - 0.083 13.0 0.3 1.5 9.1 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat Zn_ribbon_17 PF17120.5 OQS05938.1 - 7.5e-12 44.7 14.0 7.5e-12 44.7 14.0 2.1 1 1 1 2 2 2 1 Zinc-ribbon, C4HC2 type zinc_ribbon_16 PF17034.5 OQS05938.1 - 1.6e-05 25.1 7.5 1.6e-05 25.1 7.5 2.6 1 1 1 2 2 2 1 Zinc-ribbon like family zf-RING_2 PF13639.6 OQS05938.1 - 0.003 17.9 3.7 0.003 17.9 3.7 2.5 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 OQS05938.1 - 0.025 14.4 3.4 0.025 14.4 3.4 2.5 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) DZR PF12773.7 OQS05938.1 - 0.062 13.3 9.9 0.26 11.4 9.9 2.1 1 1 0 1 1 1 0 Double zinc ribbon PolC_DP2 PF03833.13 OQS05938.1 - 0.81 7.5 2.6 1.1 7.0 2.6 1.1 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 Ysc84 PF04366.12 OQS05939.1 - 1.1e-38 131.8 0.2 1.7e-38 131.3 0.2 1.3 1 0 0 1 1 1 1 Las17-binding protein actin regulator FYVE PF01363.21 OQS05939.1 - 4.3e-10 39.6 5.5 5.7e-07 29.6 0.6 2.4 2 0 0 2 2 2 2 FYVE zinc finger GATA PF00320.27 OQS05939.1 - 0.093 12.4 0.4 0.41 10.3 0.0 2.2 2 0 0 2 2 2 0 GATA zinc finger DUF2244 PF10003.9 OQS05940.1 - 0.2 11.3 0.1 0.56 9.9 0.1 1.7 1 1 0 1 1 1 0 Integral membrane protein (DUF2244) GDA1_CD39 PF01150.17 OQS05941.1 - 3.4e-45 154.5 0.0 5e-45 153.9 0.0 1.1 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family AA_permease_2 PF13520.6 OQS05942.1 - 7.8e-142 473.0 156.0 3.4e-50 171.1 49.1 3.2 3 0 0 3 3 3 3 Amino acid permease UPF0302 PF08864.10 OQS05942.1 - 3.1e-05 24.0 7.2 0.0075 16.3 0.7 3.4 3 0 0 3 3 3 2 UPF0302 domain PDEase_I PF00233.19 OQS05943.1 - 3.6e-67 226.6 5.9 1.1e-66 224.9 4.8 2.3 2 0 0 2 2 2 1 3'5'-cyclic nucleotide phosphodiesterase GAF PF01590.26 OQS05943.1 - 1e-26 94.2 0.4 6.6e-12 46.2 0.0 3.5 3 0 0 3 3 3 3 GAF domain GAF_2 PF13185.6 OQS05943.1 - 7.6e-13 48.9 0.0 4.7e-07 30.2 0.0 3.3 3 0 0 3 3 3 2 GAF domain GAF_3 PF13492.6 OQS05943.1 - 0.00011 22.6 0.0 0.0016 18.8 0.0 2.8 3 0 0 3 3 3 1 GAF domain Troponin PF00992.20 OQS05943.1 - 0.014 15.7 5.7 0.032 14.5 5.7 1.6 1 0 0 1 1 1 0 Troponin Thioredoxin_14 PF18402.1 OQS05943.1 - 0.04 13.9 2.7 0.044 13.7 0.0 2.3 2 0 0 2 2 2 0 Thioredoxin-like domain HD PF01966.22 OQS05943.1 - 0.091 13.0 0.1 0.21 11.8 0.1 1.6 1 0 0 1 1 1 0 HD domain MtrB PF05440.12 OQS05943.1 - 0.16 12.4 0.5 1.3 9.4 0.1 2.7 2 0 0 2 2 2 0 Tetrahydromethanopterin S-methyltransferase subunit B DUF4094 PF13334.6 OQS05943.1 - 6.8 7.2 6.9 9.3 6.7 2.9 3.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4094) CCDC-167 PF15188.6 OQS05943.1 - 7 7.1 12.1 32 4.9 5.2 3.7 3 1 0 3 3 3 0 Coiled-coil domain-containing protein 167 dCMP_cyt_deam_1 PF00383.23 OQS05945.1 - 1.1e-13 50.9 0.0 1.2e-13 50.8 0.0 1.0 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 OQS05945.1 - 1.3e-11 44.4 0.0 1.5e-11 44.2 0.0 1.0 1 0 0 1 1 1 1 MafB19-like deaminase Ank_2 PF12796.7 OQS05947.1 - 7e-11 42.6 0.1 1.1e-10 41.9 0.1 1.3 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQS05947.1 - 4.6e-09 36.6 0.7 2.7e-07 31.0 0.3 2.4 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 OQS05947.1 - 6.8e-08 32.6 0.4 3.7e-06 27.1 0.2 2.8 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQS05947.1 - 4.3e-07 29.7 1.2 0.0052 17.2 0.1 3.5 3 0 0 3 3 3 2 Ankyrin repeat Ank PF00023.30 OQS05947.1 - 1.5e-05 25.2 0.5 0.0044 17.4 0.2 2.6 2 0 0 2 2 2 2 Ankyrin repeat SMC_hinge PF06470.13 OQS05948.1 - 1.9e-14 54.0 0.0 7.2e-14 52.1 0.0 2.1 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain DUF1664 PF07889.12 OQS05948.1 - 2.1e-05 24.6 56.0 0.00022 21.2 3.4 7.3 3 2 3 7 7 7 3 Protein of unknown function (DUF1664) ATG16 PF08614.11 OQS05948.1 - 5.7e-05 23.4 14.0 0.00031 21.0 1.0 6.1 3 1 2 5 5 5 3 Autophagy protein 16 (ATG16) APG6_N PF17675.1 OQS05948.1 - 0.0013 19.3 16.5 0.0013 19.3 16.5 6.9 2 2 3 5 5 4 1 Apg6 coiled-coil region Baculo_PEP_C PF04513.12 OQS05948.1 - 0.002 18.2 5.2 0.002 18.2 5.2 6.7 4 2 3 7 7 7 2 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1043 PF06295.12 OQS05948.1 - 0.0036 17.3 10.1 0.0036 17.3 10.1 5.6 3 2 3 6 6 6 1 Protein of unknown function (DUF1043) AAA_13 PF13166.6 OQS05948.1 - 0.0036 16.0 22.0 0.0036 16.0 22.0 4.0 2 2 1 3 3 3 1 AAA domain IFT57 PF10498.9 OQS05948.1 - 0.0042 16.1 9.4 0.0042 16.1 9.4 5.8 4 1 2 6 6 6 3 Intra-flagellar transport protein 57 CENP-F_leu_zip PF10473.9 OQS05948.1 - 0.0072 16.4 11.3 0.0072 16.4 11.3 6.6 4 2 1 5 5 4 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 MscS_porin PF12795.7 OQS05948.1 - 0.0082 15.7 18.9 0.0082 15.7 18.9 5.8 3 2 2 5 5 4 2 Mechanosensitive ion channel porin domain DMPK_coil PF08826.10 OQS05948.1 - 0.05 13.7 0.5 0.05 13.7 0.5 5.9 5 1 1 6 6 6 0 DMPK coiled coil domain like ThiS PF02597.20 OQS05948.1 - 0.2 12.3 2.3 51 4.6 0.1 3.9 4 0 0 4 4 2 0 ThiS family DUF948 PF06103.11 OQS05948.1 - 0.69 10.2 30.3 3.3 8.0 1.0 7.0 5 1 2 7 7 7 0 Bacterial protein of unknown function (DUF948) DUF2433 PF10360.9 OQS05948.1 - 5.8 7.0 8.7 1.8 8.7 0.7 3.6 2 1 1 3 3 3 0 Protein of unknown function (DUF2433) Fez1 PF06818.15 OQS05948.1 - 8.2 6.8 71.3 0.019 15.4 9.9 4.9 2 2 3 5 5 5 0 Fez1 Pkinase PF00069.25 OQS05950.1 - 1.2e-65 221.5 0.0 1.5e-65 221.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQS05950.1 - 2.7e-32 112.1 0.0 4e-32 111.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OQS05950.1 - 0.00028 20.3 0.0 0.00041 19.8 0.0 1.3 1 0 0 1 1 1 1 Kinase-like SnoaL_2 PF12680.7 OQS05950.1 - 0.00028 21.5 0.0 0.00077 20.1 0.0 1.7 1 0 0 1 1 1 1 SnoaL-like domain APH PF01636.23 OQS05950.1 - 0.003 17.5 1.2 0.0034 17.3 0.2 1.5 2 0 0 2 2 2 1 Phosphotransferase enzyme family Pkinase_C PF00433.24 OQS05950.1 - 0.0042 17.8 1.1 0.024 15.3 1.1 2.4 1 0 0 1 1 1 1 Protein kinase C terminal domain Pkinase_fungal PF17667.1 OQS05950.1 - 0.019 13.7 0.0 0.032 13.0 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase DUF4440 PF14534.6 OQS05950.1 - 0.16 12.4 0.0 1.2 9.6 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4440) Peptidase_M16 PF00675.20 OQS05951.1 - 1.8e-40 138.4 0.2 3.1e-40 137.6 0.2 1.4 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 OQS05951.1 - 2.5e-24 86.3 0.1 1e-23 84.3 0.0 1.9 2 0 0 2 2 2 1 Peptidase M16 inactive domain Peptidase_M16_M PF16187.5 OQS05951.1 - 6.7e-11 42.0 0.1 9.7e-11 41.5 0.1 1.2 1 0 0 1 1 1 1 Middle or third domain of peptidase_M16 TPR_1 PF00515.28 OQS05952.1 - 8.4e-08 31.7 6.4 0.074 12.9 0.0 3.9 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 OQS05952.1 - 8.3e-06 25.4 2.1 0.6 9.8 0.1 3.9 4 0 0 4 4 4 2 TPR repeat TPR_2 PF07719.17 OQS05952.1 - 1.5e-05 24.7 6.1 0.25 11.6 0.0 4.6 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.6 OQS05952.1 - 0.0033 18.1 0.1 4.9 8.2 0.0 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.6 OQS05952.1 - 0.012 15.7 5.3 0.86 10.0 0.0 4.8 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_19 PF14559.6 OQS05952.1 - 0.015 15.8 4.8 1.1 9.8 0.1 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_3 PF07720.12 OQS05952.1 - 0.085 12.9 0.4 0.085 12.9 0.4 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat YqaH PF17448.2 OQS05952.1 - 0.11 12.8 0.3 2.4 8.5 0.0 2.8 2 0 0 2 2 2 0 Uncharacterized YqaH-like Amidase_3 PF01520.18 OQS05952.1 - 0.18 11.9 1.4 7.3 6.7 0.1 2.7 3 0 0 3 3 3 0 N-acetylmuramoyl-L-alanine amidase TPR_12 PF13424.6 OQS05952.1 - 0.22 11.8 0.8 4.6 7.6 0.0 3.2 4 0 0 4 4 4 0 Tetratricopeptide repeat RTT107_BRCT_6 PF16771.5 OQS05952.1 - 0.3 11.2 2.0 0.35 11.0 0.1 1.9 2 0 0 2 2 2 0 Regulator of Ty1 transposition protein 107 BRCT domain Fis1_TPR_C PF14853.6 OQS05952.1 - 0.7 10.0 4.8 16 5.6 0.1 3.8 5 0 0 5 5 5 0 Fis1 C-terminal tetratricopeptide repeat Ank_4 PF13637.6 OQS05953.1 - 2.5e-16 59.8 2.1 1.1e-09 38.7 0.1 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 OQS05953.1 - 7.7e-14 52.0 0.1 1.2e-13 51.4 0.1 1.2 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OQS05953.1 - 1.4e-12 46.6 0.4 1.1e-07 31.5 0.1 3.5 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 OQS05953.1 - 1.9e-12 47.1 0.8 1.8e-08 34.4 0.4 2.3 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 OQS05953.1 - 5e-12 45.7 0.2 5.6e-09 36.1 0.1 2.7 2 0 0 2 2 2 2 Ankyrin repeat DUF1069 PF06370.11 OQS05954.1 - 0.046 13.3 0.0 0.051 13.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1069) DEAD PF00270.29 OQS05956.1 - 3.8e-49 166.8 1.4 5e-49 166.4 0.2 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OQS05956.1 - 1.5e-19 70.4 0.2 2.3e-18 66.6 0.0 2.6 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 OQS05956.1 - 6.4e-12 45.8 0.0 6.4e-12 45.8 0.0 2.3 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 OQS05956.1 - 0.0077 16.5 2.4 0.011 16.1 0.2 2.3 2 0 0 2 2 2 1 AAA domain EPL1 PF10513.9 OQS05956.1 - 0.017 15.5 4.4 0.049 14.0 4.4 1.9 1 0 0 1 1 1 0 Enhancer of polycomb-like DUF4217 PF13959.6 OQS05956.1 - 0.078 13.2 0.0 0.23 11.7 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4217) TusA PF01206.17 OQS05956.1 - 0.12 12.2 0.0 0.36 10.7 0.0 1.8 1 0 0 1 1 1 0 Sulfurtransferase TusA DEAD PF00270.29 OQS05957.1 - 1.2e-45 155.5 1.1 1.2e-45 155.5 1.1 2.1 3 1 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OQS05957.1 - 2.2e-19 69.9 0.4 9.3e-19 67.8 0.0 2.3 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 OQS05957.1 - 3.1e-10 40.3 0.6 7.1e-10 39.1 0.1 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DUF4217 PF13959.6 OQS05957.1 - 0.0047 17.1 0.1 0.01 16.0 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) AAA_22 PF13401.6 OQS05957.1 - 0.018 15.3 3.2 0.031 14.6 1.1 2.4 2 1 0 2 2 2 0 AAA domain Sel1 PF08238.12 OQS05958.1 - 1.5e-15 57.3 6.6 7.1e-06 26.5 0.2 5.1 6 0 0 6 6 6 4 Sel1 repeat zf-RING_2 PF13639.6 OQS05959.1 - 8e-13 48.5 12.8 1.2e-12 47.9 12.8 1.3 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 OQS05959.1 - 1.9e-09 37.7 11.5 4.4e-09 36.5 11.5 1.7 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 OQS05959.1 - 2.7e-07 30.3 12.5 4.6e-07 29.6 12.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 OQS05959.1 - 1.2e-06 28.1 10.5 1.2e-06 28.1 10.5 2.1 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4 PF00097.25 OQS05959.1 - 1.7e-05 24.6 12.9 3e-05 23.8 12.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OQS05959.1 - 1.7e-05 24.7 8.2 3.9e-05 23.6 8.2 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 OQS05959.1 - 2.3e-05 24.1 11.5 3.8e-05 23.5 11.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 OQS05959.1 - 4.2e-05 23.5 9.9 0.00035 20.6 9.9 2.1 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.6 OQS05959.1 - 9.9e-05 22.2 12.4 0.00014 21.7 12.4 1.3 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 OQS05959.1 - 0.00059 19.6 9.3 0.0011 18.8 9.2 1.5 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 RINGv PF12906.7 OQS05959.1 - 0.012 15.7 9.5 0.027 14.6 9.5 1.6 1 1 0 1 1 1 0 RING-variant domain Zn_ribbon_17 PF17120.5 OQS05959.1 - 0.052 13.2 9.6 0.11 12.1 9.6 1.6 1 1 0 1 1 1 0 Zinc-ribbon, C4HC2 type DASH_Ask1 PF08655.10 OQS05959.1 - 0.081 12.8 0.1 0.2 11.6 0.1 1.6 1 0 0 1 1 1 0 DASH complex subunit Ask1 FANCL_C PF11793.8 OQS05959.1 - 0.094 12.9 12.3 3.4 7.9 12.3 2.4 1 1 0 1 1 1 0 FANCL C-terminal domain zf-HC5HC2H PF13771.6 OQS05959.1 - 0.29 11.4 8.3 0.87 9.9 8.3 1.8 1 1 0 1 1 1 0 PHD-like zinc-binding domain zf-RING_4 PF14570.6 OQS05959.1 - 1.6 8.6 10.7 3.1 7.7 10.5 1.6 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.6 OQS05959.1 - 7.6 6.8 10.7 36 4.6 10.5 2.2 1 1 2 3 3 3 0 zinc finger of C3HC4-type, RING NAPRTase_N PF17767.1 OQS05961.1 - 1.2e-34 119.4 0.0 3.3e-34 118.0 0.0 1.8 2 0 0 2 2 2 1 Nicotinate phosphoribosyltransferase (NAPRTase) N-terminal domain NAPRTase_C PF17956.1 OQS05961.1 - 3.5e-31 107.9 0.0 6.2e-31 107.1 0.0 1.4 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase C-terminal domain NAPRTase PF04095.16 OQS05961.1 - 2.7e-10 40.3 0.0 0.00076 19.2 0.0 2.2 2 0 0 2 2 2 2 Nicotinate phosphoribosyltransferase (NAPRTase) family Sugar_tr PF00083.24 OQS05962.1 - 4.4e-39 134.6 22.8 2.6e-30 105.7 9.3 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 OQS05962.1 - 9.6e-36 123.4 41.6 2.5e-31 108.9 25.8 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily ATG22 PF11700.8 OQS05962.1 - 0.026 13.2 9.4 0.0066 15.1 1.7 2.4 2 0 0 2 2 2 0 Vacuole effluxer Atg22 like AAA_6 PF12774.7 OQS05963.1 - 3.1e-121 404.4 0.0 2.7e-120 401.3 0.0 2.4 2 0 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 OQS05963.1 - 1.3e-99 334.0 12.9 1.3e-99 334.0 12.9 3.9 4 1 1 5 5 5 1 Dynein heavy chain, N-terminal region 2 AAA_9 PF12781.7 OQS05963.1 - 7.9e-70 234.4 1.9 3.4e-69 232.3 0.0 3.0 2 0 0 2 2 2 1 ATP-binding dynein motor region Na_Ca_ex PF01699.24 OQS05963.1 - 3.5e-67 225.1 77.9 3.1e-19 69.4 13.5 5.2 5 0 0 5 5 5 4 Sodium/calcium exchanger protein AAA_8 PF12780.7 OQS05963.1 - 3.1e-52 177.5 1.0 5.4e-51 173.4 0.0 3.5 4 0 0 4 4 4 1 P-loop containing dynein motor region D4 DHC_N1 PF08385.12 OQS05963.1 - 9.2e-38 130.2 0.6 3e-37 128.5 0.0 2.2 2 0 0 2 2 2 1 Dynein heavy chain, N-terminal region 1 AAA_5 PF07728.14 OQS05963.1 - 4.9e-37 127.0 0.0 8.8e-22 77.6 0.0 5.3 5 0 0 5 5 4 3 AAA domain (dynein-related subfamily) AAA_lid_11 PF18198.1 OQS05963.1 - 1.8e-35 122.2 0.1 5.1e-35 120.7 0.1 1.9 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain Dynein_C PF18199.1 OQS05963.1 - 1.5e-34 119.6 0.1 4.6e-34 118.0 0.1 1.9 1 0 0 1 1 1 1 Dynein heavy chain C-terminal domain Dynein_heavy PF03028.15 OQS05963.1 - 1.1e-33 115.8 0.0 1.4e-30 105.8 0.1 3.3 2 0 0 2 2 2 1 Dynein heavy chain region D6 P-loop domain MT PF12777.7 OQS05963.1 - 7e-30 104.2 8.8 1.2e-29 103.4 7.3 2.2 2 0 0 2 2 2 1 Microtubule-binding stalk of dynein motor AAA_7 PF12775.7 OQS05963.1 - 1.2e-25 90.1 1.0 4e-22 78.6 0.0 3.6 3 0 0 3 3 3 2 P-loop containing dynein motor region Cupin_8 PF13621.6 OQS05963.1 - 2e-18 67.0 0.1 6.2e-18 65.4 0.1 1.9 1 0 0 1 1 1 1 Cupin-like domain JmjC PF02373.22 OQS05963.1 - 2.3e-08 34.5 0.1 6.7e-08 33.0 0.1 1.9 1 0 0 1 1 1 1 JmjC domain, hydroxylase AAA PF00004.29 OQS05963.1 - 1.4e-07 32.0 0.0 0.44 11.0 0.0 5.1 4 0 0 4 4 4 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 OQS05963.1 - 8.1e-07 29.6 12.5 0.18 12.1 0.0 7.1 9 0 0 9 9 4 2 AAA ATPase domain AAA_22 PF13401.6 OQS05963.1 - 5.7e-06 26.7 2.4 4.4 7.6 0.0 5.8 5 0 0 5 5 5 1 AAA domain Cupin_4 PF08007.12 OQS05963.1 - 8.8e-06 25.4 5.1 1.4e-05 24.7 0.1 3.6 3 1 0 3 3 3 1 Cupin superfamily protein IstB_IS21 PF01695.17 OQS05963.1 - 0.00017 21.3 0.1 0.81 9.4 0.0 3.7 4 0 0 4 4 4 2 IstB-like ATP binding protein AAA_18 PF13238.6 OQS05963.1 - 0.0019 18.8 0.0 0.48 11.0 0.0 4.0 3 0 0 3 3 3 1 AAA domain AAA_24 PF13479.6 OQS05963.1 - 0.0019 18.0 0.0 0.22 11.2 0.0 3.1 3 0 0 3 3 2 1 AAA domain ABC_tran PF00005.27 OQS05963.1 - 0.0025 18.3 0.0 0.46 11.0 0.0 4.0 3 0 0 3 3 2 1 ABC transporter RsgA_GTPase PF03193.16 OQS05963.1 - 0.0039 17.1 6.3 0.054 13.4 0.0 4.6 6 0 0 6 6 3 1 RsgA GTPase Cupin_2 PF07883.11 OQS05963.1 - 0.0051 16.5 0.0 0.014 15.1 0.0 1.7 1 0 0 1 1 1 1 Cupin domain AAA_33 PF13671.6 OQS05963.1 - 0.0063 16.7 0.0 2.1 8.5 0.0 3.7 3 0 0 3 3 3 1 AAA domain AAA_30 PF13604.6 OQS05963.1 - 0.0088 15.8 0.1 1.1 8.9 0.0 2.9 3 0 0 3 3 2 1 AAA domain ATPase_2 PF01637.18 OQS05963.1 - 0.0093 15.9 0.0 0.37 10.6 0.0 3.3 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea RNA_helicase PF00910.22 OQS05963.1 - 0.013 15.8 0.1 8.5 6.8 0.0 3.9 3 0 0 3 3 3 0 RNA helicase AAA_29 PF13555.6 OQS05963.1 - 0.019 14.7 0.0 0.5 10.2 0.0 3.1 3 0 0 3 3 2 0 P-loop containing region of AAA domain Rad17 PF03215.15 OQS05963.1 - 0.024 14.6 0.7 8.7 6.2 0.0 4.4 5 0 0 5 5 4 0 Rad17 P-loop domain AraC_binding PF02311.19 OQS05963.1 - 0.024 14.5 0.1 0.087 12.7 0.1 2.0 1 0 0 1 1 1 0 AraC-like ligand binding domain AAA_28 PF13521.6 OQS05963.1 - 0.024 14.9 0.0 2.5 8.3 0.0 3.6 4 0 0 4 4 3 0 AAA domain Sigma54_activat PF00158.26 OQS05963.1 - 0.024 14.3 0.0 8.8 6.0 0.0 2.7 2 0 0 2 2 2 0 Sigma-54 interaction domain MIG-14_Wnt-bd PF06664.12 OQS05963.1 - 0.12 11.5 11.5 1.3 8.2 5.2 2.7 2 0 0 2 2 2 0 Wnt-binding factor required for Wnt secretion CC2-LZ PF16516.5 OQS05963.1 - 0.13 12.6 10.9 0.88 10.0 0.7 4.9 3 0 0 3 3 3 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator Prefoldin_3 PF13758.6 OQS05963.1 - 0.22 11.6 2.5 7.8 6.6 0.1 3.3 2 0 0 2 2 2 0 Prefoldin subunit DUF1673 PF07895.11 OQS05963.1 - 3 7.5 6.6 6.3 6.4 0.3 3.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1673) RrnaAD PF00398.20 OQS05964.1 - 3.7e-59 200.0 0.0 1.2e-57 195.0 0.0 2.1 2 0 0 2 2 2 1 Ribosomal RNA adenine dimethylase Methyltransf_16 PF10294.9 OQS05964.1 - 3.6e-32 111.5 0.1 7.9e-31 107.1 0.0 2.1 2 0 0 2 2 2 1 Lysine methyltransferase Methyltransf_25 PF13649.6 OQS05964.1 - 6.1e-12 46.1 0.2 6.2e-08 33.2 0.0 3.1 3 1 0 3 3 2 2 Methyltransferase domain Methyltransf_31 PF13847.6 OQS05964.1 - 3.2e-09 36.8 0.1 0.0051 16.6 0.0 3.3 3 0 0 3 3 3 2 Methyltransferase domain Methyltransf_23 PF13489.6 OQS05964.1 - 3.9e-09 36.6 0.0 0.0026 17.6 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_11 PF08241.12 OQS05964.1 - 1e-08 35.7 0.1 7.8e-07 29.7 0.0 2.8 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 OQS05964.1 - 5.8e-07 30.2 0.2 0.00074 20.2 0.0 3.2 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_4 PF02390.17 OQS05964.1 - 4.8e-06 26.2 0.3 2.9e-05 23.6 0.1 2.2 2 0 0 2 2 2 1 Putative methyltransferase PrmA PF06325.13 OQS05964.1 - 6.4e-06 25.8 0.0 0.033 13.6 0.0 2.2 2 0 0 2 2 2 2 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 OQS05964.1 - 7.8e-06 25.5 0.0 0.086 12.4 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase small domain PCMT PF01135.19 OQS05964.1 - 4.7e-05 23.3 0.0 0.0041 16.9 0.0 2.2 2 0 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) NodS PF05401.11 OQS05964.1 - 6.6e-05 22.6 0.1 0.0076 15.9 0.0 2.5 2 0 0 2 2 2 1 Nodulation protein S (NodS) Ubie_methyltran PF01209.18 OQS05964.1 - 0.00029 20.2 0.0 0.00058 19.3 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family UPF0020 PF01170.18 OQS05964.1 - 0.0016 18.2 0.0 0.0031 17.2 0.0 1.4 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Cons_hypoth95 PF03602.15 OQS05964.1 - 0.0018 18.0 0.0 0.4 10.3 0.0 2.3 2 0 0 2 2 2 1 Conserved hypothetical protein 95 DREV PF05219.12 OQS05964.1 - 0.0067 15.6 0.0 0.41 9.7 0.0 2.4 2 0 0 2 2 2 1 DREV methyltransferase Met_10 PF02475.16 OQS05964.1 - 0.015 15.0 0.1 0.33 10.7 0.0 2.3 2 0 0 2 2 2 0 Met-10+ like-protein PRMT5 PF05185.16 OQS05964.1 - 0.043 13.7 0.0 0.17 11.7 0.0 1.9 2 0 0 2 2 2 0 PRMT5 arginine-N-methyltransferase tRNA_U5-meth_tr PF05958.11 OQS05964.1 - 0.059 12.3 0.0 0.89 8.5 0.0 2.1 2 0 0 2 2 2 0 tRNA (Uracil-5-)-methyltransferase GidB PF02527.15 OQS05964.1 - 0.062 12.6 0.1 3.1 7.1 0.0 2.2 2 0 0 2 2 2 0 rRNA small subunit methyltransferase G Methyltransf_15 PF09445.10 OQS05964.1 - 0.083 12.5 0.0 0.22 11.1 0.0 1.7 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase DUF2089 PF09862.9 OQS05965.1 - 0.0026 17.8 0.0 0.005 16.9 0.0 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF2089) Exonuc_VII_S PF02609.16 OQS05965.1 - 0.14 12.3 1.3 0.23 11.5 0.8 1.6 2 0 0 2 2 2 0 Exonuclease VII small subunit Ribosomal_L11_N PF03946.14 OQS05966.1 - 7.6e-26 89.7 0.0 1.3e-25 88.9 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.19 OQS05966.1 - 9.1e-26 90.2 0.0 1.2e-25 89.7 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain Peptidase_S10 PF00450.22 OQS05967.1 - 0 1222.9 2.8 5.1e-126 421.5 0.1 3.0 3 0 0 3 3 3 3 Serine carboxypeptidase Say1_Mug180 PF10340.9 OQS05967.1 - 0.00011 21.2 0.3 3.3 6.5 0.0 3.5 3 0 0 3 3 3 3 Steryl acetyl hydrolase DUF3895 PF13034.6 OQS05967.1 - 0.00016 21.6 3.9 0.072 13.1 0.1 3.8 4 0 0 4 4 4 2 Protein of unknown function (DUF3895) Humanin PF15040.6 OQS05967.1 - 0.0094 15.4 0.3 21 4.6 0.0 3.5 3 0 0 3 3 3 1 Humanin family PAS_10 PF13596.6 OQS05968.1 - 0.13 12.8 0.0 0.19 12.3 0.0 1.3 1 0 0 1 1 1 0 PAS domain ABC_membrane PF00664.23 OQS05969.1 - 2.6e-53 181.4 1.7 4.4e-53 180.7 1.7 1.4 1 0 0 1 1 1 1 ABC transporter transmembrane region DUF1853 PF08907.11 OQS05969.1 - 4.8e-33 115.1 0.1 7.3e-33 114.5 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1853) ABC_tran PF00005.27 OQS05969.1 - 6.7e-30 104.4 0.0 2.6e-29 102.5 0.0 2.1 2 0 0 2 2 2 1 ABC transporter DNA_pol_A_exo1 PF01612.20 OQS05969.1 - 1.5e-12 47.6 0.0 3.5e-12 46.4 0.0 1.5 1 0 0 1 1 1 1 3'-5' exonuclease tRNA_edit PF04073.15 OQS05969.1 - 7e-12 45.5 0.0 1.4e-11 44.5 0.0 1.5 1 0 0 1 1 1 1 Aminoacyl-tRNA editing domain SMC_N PF02463.19 OQS05969.1 - 7.9e-08 32.0 0.1 2.9e-05 23.6 0.1 2.5 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_30 PF13604.6 OQS05969.1 - 0.0043 16.8 0.0 0.0089 15.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 OQS05969.1 - 0.0048 17.3 0.7 0.2 12.1 0.7 2.8 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 OQS05969.1 - 0.0048 17.2 0.1 0.043 14.1 0.0 2.7 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 OQS05969.1 - 0.0061 17.0 0.1 0.022 15.1 0.1 2.0 1 1 0 1 1 1 1 AAA ATPase domain Rad17 PF03215.15 OQS05969.1 - 0.0068 16.4 0.0 0.019 14.9 0.0 1.7 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_29 PF13555.6 OQS05969.1 - 0.011 15.5 0.0 0.03 14.0 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_21 PF13304.6 OQS05969.1 - 0.063 13.1 0.4 2.3 7.9 0.0 3.1 3 0 0 3 3 3 0 AAA domain, putative AbiEii toxin, Type IV TA system ABC_ATPase PF09818.9 OQS05969.1 - 0.063 12.1 0.1 0.11 11.2 0.1 1.3 1 0 0 1 1 1 0 Predicted ATPase of the ABC class CAMSAP_CH PF11971.8 OQS05969.1 - 0.13 12.1 0.1 1.8 8.5 0.0 2.9 3 0 0 3 3 3 0 CAMSAP CH domain Carboxyl_trans PF01039.22 OQS05970.1 - 1.4e-156 522.0 0.0 1.9e-156 521.6 0.0 1.1 1 0 0 1 1 1 1 Carboxyl transferase domain ECH_1 PF00378.20 OQS05970.1 - 0.4 9.9 2.4 0.24 10.7 0.1 1.8 2 0 0 2 2 2 0 Enoyl-CoA hydratase/isomerase zf-C3HC4_3 PF13920.6 OQS05971.1 - 0.00063 19.6 17.3 0.0039 17.0 17.3 2.0 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 OQS05971.1 - 2.7 7.9 14.4 12 5.8 14.4 2.0 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 Mis12 PF05859.12 OQS05972.1 - 1.3e-15 57.7 1.8 1.3e-15 57.7 1.8 1.6 2 0 0 2 2 2 1 Mis12 protein Tektin PF03148.14 OQS05972.1 - 0.0018 17.1 4.8 0.0028 16.5 4.8 1.2 1 0 0 1 1 1 1 Tektin family APG6_N PF17675.1 OQS05972.1 - 0.0047 17.4 3.8 0.012 16.1 3.8 1.6 1 0 0 1 1 1 1 Apg6 coiled-coil region DUF3450 PF11932.8 OQS05972.1 - 0.0055 16.0 4.3 0.0083 15.5 4.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3450) Filament PF00038.21 OQS05972.1 - 0.011 15.3 8.6 0.012 15.2 7.4 1.6 1 1 0 1 1 1 0 Intermediate filament protein TMF_DNA_bd PF12329.8 OQS05972.1 - 0.019 14.9 1.0 0.047 13.7 1.0 1.7 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding Laminin_II PF06009.12 OQS05972.1 - 0.02 14.9 4.3 0.53 10.3 3.0 2.3 1 1 1 2 2 2 0 Laminin Domain II Cep57_CLD_2 PF14197.6 OQS05972.1 - 0.036 14.2 7.6 0.22 11.6 4.4 2.3 2 0 0 2 2 2 0 Centrosome localisation domain of PPC89 Fzo_mitofusin PF04799.13 OQS05972.1 - 0.046 13.3 8.1 0.57 9.7 6.0 2.3 1 1 1 2 2 2 0 fzo-like conserved region CTK3_C PF12350.8 OQS05972.1 - 0.059 13.5 0.1 0.12 12.6 0.1 1.6 1 0 0 1 1 1 0 CTD kinase subunit gamma CTK3 C-terminus ANAPC_CDC26 PF10471.9 OQS05972.1 - 0.064 14.1 2.3 0.1 13.4 1.0 2.1 2 0 0 2 2 1 0 Anaphase-promoting complex APC subunit CDC26 ApoO PF09769.9 OQS05972.1 - 0.069 13.1 0.6 0.16 11.9 0.6 1.8 1 0 0 1 1 1 0 Apolipoprotein O DASH_Spc19 PF08287.11 OQS05972.1 - 0.07 13.0 5.3 0.12 12.3 4.0 1.8 1 1 0 2 2 2 0 Spc19 DUF4140 PF13600.6 OQS05972.1 - 0.13 12.7 1.8 0.32 11.5 1.3 1.9 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) DUF4404 PF14357.6 OQS05972.1 - 0.28 11.9 4.3 0.47 11.1 2.6 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4404) Phage_Mu_Gam PF07352.12 OQS05972.1 - 0.32 10.9 6.2 0.24 11.3 3.9 2.0 2 1 0 2 2 2 0 Bacteriophage Mu Gam like protein Spc24 PF08286.11 OQS05972.1 - 0.33 11.2 4.2 0.51 10.6 2.6 2.1 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 ATG_C PF09333.11 OQS05972.1 - 0.36 11.2 3.8 9.3 6.7 0.3 2.8 3 1 0 4 4 3 0 Autophagy-related protein C terminal domain Not3 PF04065.15 OQS05972.1 - 0.64 9.4 7.2 0.47 9.8 5.6 1.6 1 1 0 1 1 1 0 Not1 N-terminal domain, CCR4-Not complex component Occludin_ELL PF07303.13 OQS05972.1 - 0.84 10.4 5.1 1.2 9.9 2.4 2.3 2 0 0 2 2 2 0 Occludin homology domain ABC_tran_CTD PF16326.5 OQS05972.1 - 0.99 9.7 4.8 1.3 9.4 3.5 1.9 2 0 0 2 2 1 0 ABC transporter C-terminal domain DUF5339 PF17274.2 OQS05972.1 - 1 10.3 7.3 3 8.8 4.3 2.7 3 0 0 3 3 3 0 Family of unknown function (DUF5339) TipAS PF07739.13 OQS05972.1 - 1.2 9.7 5.4 2.3 8.8 4.0 2.0 1 1 1 2 2 2 0 TipAS antibiotic-recognition domain DUF16 PF01519.16 OQS05972.1 - 1.8 9.1 8.4 0.92 10.0 5.4 2.0 1 1 1 2 2 2 0 Protein of unknown function DUF16 bZIP_2 PF07716.15 OQS05972.1 - 1.9 8.6 5.0 0.47 10.6 1.1 2.1 2 1 0 2 2 1 0 Basic region leucine zipper Fib_alpha PF08702.10 OQS05972.1 - 2 8.6 9.2 1.8 8.8 4.8 2.4 1 1 2 4 4 4 0 Fibrinogen alpha/beta chain family Exonuc_VII_L PF02601.15 OQS05972.1 - 2.6 7.5 8.6 2.8 7.4 7.9 1.3 1 1 0 1 1 1 0 Exonuclease VII, large subunit IES5 PF17335.2 OQS05973.1 - 0.02 15.1 0.1 0.082 13.2 0.0 2.1 2 0 0 2 2 2 0 Ino80 complex subunit 5 Exo_endo_phos PF03372.23 OQS05974.1 - 5.3e-15 55.6 0.1 7.2e-15 55.1 0.1 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Glyco_hydro_30 PF02055.16 OQS05975.1 - 7.8e-175 580.9 9.2 3.1e-90 302.7 1.2 2.1 2 0 0 2 2 2 2 Glycosyl hydrolase family 30 TIM-barrel domain Ricin_B_lectin PF00652.22 OQS05975.1 - 9.9e-25 87.2 14.1 1.5e-11 44.6 4.6 4.3 2 2 2 4 4 4 4 Ricin-type beta-trefoil lectin domain Glyco_hydro_30C PF17189.4 OQS05975.1 - 2.3e-17 62.9 5.6 5.8e-08 32.8 0.3 3.3 3 0 0 3 3 3 2 Glycosyl hydrolase family 30 beta sandwich domain Glyco_hydro_59 PF02057.15 OQS05975.1 - 5.1e-16 58.8 0.6 5.5e-09 35.7 0.1 2.7 2 0 0 2 2 2 2 Glycosyl hydrolase family 59 RicinB_lectin_2 PF14200.6 OQS05975.1 - 8.7e-09 36.0 4.4 0.0033 18.1 0.0 3.8 3 1 1 4 4 4 2 Ricin-type beta-trefoil lectin domain-like Glyco_hydr_30_2 PF14587.6 OQS05975.1 - 4.1e-06 26.6 0.3 1.9 8.0 0.0 3.6 4 0 0 4 4 4 3 O-Glycosyl hydrolase family 30 Alpha-L-AF_C PF06964.12 OQS05975.1 - 0.0038 17.4 0.1 2.9 8.0 0.0 2.5 2 0 0 2 2 2 2 Alpha-L-arabinofuranosidase C-terminal domain Cyc-maltodext_C PF10438.9 OQS05975.1 - 0.023 14.8 0.6 7.1 6.8 0.1 2.8 2 0 0 2 2 2 0 Cyclo-malto-dextrinase C-terminal domain MPC PF03650.13 OQS05976.1 - 4e-37 126.7 0.2 4.4e-37 126.6 0.2 1.0 1 0 0 1 1 1 1 Mitochondrial pyruvate carriers Varsurf_PPLC PF03490.13 OQS05977.1 - 0.014 15.4 0.0 0.031 14.2 0.0 1.6 1 0 0 1 1 1 0 Variant-surface-glycoprotein phospholipase C DiS_P_DiS PF06750.13 OQS05977.1 - 0.11 12.6 0.3 1.6 8.9 0.2 2.3 2 0 0 2 2 2 0 Bacterial Peptidase A24 N-terminal domain Pkinase_Tyr PF07714.17 OQS05978.1 - 1.3e-47 162.3 0.0 1.9e-47 161.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OQS05978.1 - 4.7e-35 121.2 0.0 6.8e-35 120.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain HSF_DNA-bind PF00447.17 OQS05978.1 - 6.6e-26 90.8 0.7 2.3e-25 89.0 0.3 2.1 2 0 0 2 2 2 1 HSF-type DNA-binding Kdo PF06293.14 OQS05978.1 - 0.0082 15.5 0.0 0.016 14.6 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family DNA_pol_B_exo2 PF10108.9 OQS05978.1 - 0.077 12.7 0.1 0.14 11.8 0.1 1.3 1 0 0 1 1 1 0 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB Proteasom_PSMB PF10508.9 OQS05978.1 - 0.21 10.1 0.0 0.31 9.5 0.0 1.2 1 0 0 1 1 1 0 Proteasome non-ATPase 26S subunit PTEN_C2 PF10409.9 OQS05979.1 - 2.3e-19 69.5 0.0 4e-19 68.7 0.0 1.4 1 0 0 1 1 1 1 C2 domain of PTEN tumour-suppressor protein PH PF00169.29 OQS05979.1 - 3.5e-15 56.4 0.3 1.2e-14 54.7 0.2 1.9 2 0 0 2 2 2 1 PH domain PH_11 PF15413.6 OQS05979.1 - 3.7e-07 30.5 1.9 5e-06 26.9 1.9 2.5 1 1 0 1 1 1 1 Pleckstrin homology domain Y_phosphatase PF00102.27 OQS05979.1 - 6e-07 29.3 0.0 9.5e-07 28.6 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 OQS05979.1 - 9.3e-06 25.8 0.0 2e-05 24.7 0.0 1.5 1 0 0 1 1 1 1 Tyrosine phosphatase family DSPc PF00782.20 OQS05979.1 - 2.1e-05 24.4 0.1 4.4e-05 23.3 0.1 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.6 OQS05979.1 - 0.021 14.9 0.0 0.062 13.4 0.0 1.7 1 0 0 1 1 1 0 Inositol hexakisphosphate Y_phosphatase2 PF03162.13 OQS05979.1 - 0.022 14.3 1.8 0.063 12.9 0.2 2.0 1 1 1 2 2 2 0 Tyrosine phosphatase family PH_9 PF15410.6 OQS05979.1 - 0.029 14.7 0.1 0.41 11.0 0.1 2.5 2 1 0 2 2 2 0 Pleckstrin homology domain PH_8 PF15409.6 OQS05979.1 - 0.057 13.7 0.0 0.23 11.7 0.0 2.0 2 0 0 2 2 2 0 Pleckstrin homology domain PspA_IM30 PF04012.12 OQS05980.1 - 2.7e-05 23.9 13.0 4.3e-05 23.2 13.0 1.2 1 0 0 1 1 1 1 PspA/IM30 family KASH_CCD PF14662.6 OQS05980.1 - 0.0038 17.1 19.4 0.0066 16.3 19.4 1.5 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 or KASH Cep57_CLD_2 PF14197.6 OQS05980.1 - 0.011 15.8 10.2 0.011 15.8 10.2 3.0 2 2 1 3 3 3 0 Centrosome localisation domain of PPC89 DUF1515 PF07439.11 OQS05980.1 - 0.014 15.4 1.7 0.014 15.4 1.7 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1515) ADIP PF11559.8 OQS05980.1 - 0.076 13.1 18.9 0.054 13.6 16.1 1.9 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding Leu_zip PF15294.6 OQS05980.1 - 0.13 11.8 20.9 0.94 8.9 19.7 2.0 1 1 1 2 2 2 0 Leucine zipper Band_7_1 PF13421.6 OQS05980.1 - 0.15 11.8 2.0 11 5.7 0.0 2.5 1 1 1 2 2 2 0 SPFH domain-Band 7 family Mod_r PF07200.13 OQS05980.1 - 0.19 11.8 18.8 0.16 12.1 9.9 2.4 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein Exonuc_VII_L PF02601.15 OQS05980.1 - 0.22 11.1 8.5 0.28 10.7 8.5 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit UPF0242 PF06785.11 OQS05980.1 - 0.33 11.0 21.7 2 8.5 9.9 2.3 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Baculo_PEP_C PF04513.12 OQS05980.1 - 0.33 11.0 6.3 4.6 7.3 2.6 2.2 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus 5_nucleotid PF05761.14 OQS05980.1 - 0.39 9.6 6.0 0.4 9.5 5.3 1.3 1 1 0 1 1 1 0 5' nucleotidase family Apolipoprotein PF01442.18 OQS05980.1 - 0.43 10.4 16.7 3.3 7.6 16.7 2.0 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain Prominin PF05478.11 OQS05980.1 - 0.5 8.3 6.9 0.72 7.7 6.9 1.3 1 0 0 1 1 1 0 Prominin Syntaxin-6_N PF09177.11 OQS05980.1 - 0.58 10.7 9.2 2.2 8.9 8.3 2.3 1 1 1 2 2 2 0 Syntaxin 6, N-terminal DUF4407 PF14362.6 OQS05980.1 - 0.64 9.3 10.8 0.89 8.8 10.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF4061 PF13270.6 OQS05980.1 - 0.71 10.2 13.2 0.83 10.0 9.9 2.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4061) GvpG PF05120.12 OQS05980.1 - 0.77 9.8 9.7 0.27 11.3 3.6 2.8 1 1 0 2 2 2 0 Gas vesicle protein G HIP1_clath_bdg PF16515.5 OQS05980.1 - 1.4 9.6 18.8 0.82 10.3 4.8 2.7 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 DUF2203 PF09969.9 OQS05980.1 - 1.5 9.5 10.5 0.7 10.6 3.0 2.5 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) FAM76 PF16046.5 OQS05980.1 - 1.6 8.0 19.0 15 4.9 19.0 2.1 1 1 0 1 1 1 0 FAM76 protein DUF1664 PF07889.12 OQS05980.1 - 1.7 8.7 11.2 6.8 6.8 2.6 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Fib_alpha PF08702.10 OQS05980.1 - 3.2 7.9 12.6 3.7 7.7 8.3 2.4 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family PIN_8 PF18476.1 OQS05980.1 - 3.2 7.5 10.7 1.5 8.6 1.7 2.1 1 1 1 2 2 2 0 PIN like domain TMPIT PF07851.13 OQS05980.1 - 3.8 6.7 12.2 1.1 8.5 7.6 1.9 1 1 1 2 2 2 0 TMPIT-like protein DUF883 PF05957.13 OQS05980.1 - 5.2 7.7 9.3 1.6 9.4 0.4 2.8 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) TolA_bind_tri PF16331.5 OQS05980.1 - 5.3 7.2 22.0 3.6 7.7 5.0 3.8 2 2 1 3 3 3 0 TolA binding protein trimerisation CorA PF01544.18 OQS05980.1 - 5.8 6.1 11.7 3 7.1 9.1 1.7 1 1 1 2 2 2 0 CorA-like Mg2+ transporter protein V-ATPase_G_2 PF16999.5 OQS05980.1 - 6.9 7.1 12.0 8.6 6.8 2.9 2.5 1 1 1 2 2 2 0 Vacuolar (H+)-ATPase G subunit DUF745 PF05335.13 OQS05980.1 - 7.3 6.3 13.5 1.3 8.7 2.2 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF745) RVT_1 PF00078.27 OQS05981.1 - 3.4e-05 23.5 0.0 3.5e-05 23.4 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-RVT PF13966.6 OQS05982.1 - 0.0057 17.3 0.6 0.0057 17.3 0.6 1.9 2 0 0 2 2 2 1 zinc-binding in reverse transcriptase zf-C3HC4_3 PF13920.6 OQS05984.1 - 1.5e-13 50.4 11.7 3e-13 49.4 11.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 OQS05984.1 - 3.2e-08 33.3 13.2 3.2e-08 33.3 11.6 1.8 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 OQS05984.1 - 0.00057 20.2 12.7 0.0013 19.0 12.7 1.7 1 0 0 1 1 1 1 Ring finger domain DUF5304 PF17230.2 OQS05984.1 - 0.0037 17.5 0.5 2.4 8.4 0.1 2.3 2 0 0 2 2 2 2 Family of unknown function (DUF5304) zf-RING_5 PF14634.6 OQS05984.1 - 0.03 14.3 12.6 0.059 13.3 12.6 1.5 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_11 PF17123.5 OQS05984.1 - 0.28 11.0 6.4 0.32 10.8 0.7 3.1 2 1 1 3 3 3 0 RING-like zinc finger Arf PF00025.21 OQS05985.1 - 1.8e-76 255.5 0.1 2e-76 255.3 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 OQS05985.1 - 1.3e-14 54.5 0.0 1.9e-14 53.9 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 OQS05985.1 - 3.6e-13 49.4 0.0 3.9e-13 49.3 0.0 1.1 1 0 0 1 1 1 1 Ras family SRPRB PF09439.10 OQS05985.1 - 6.9e-13 48.4 0.0 9.1e-13 48.0 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 OQS05985.1 - 5.1e-12 45.6 0.4 8.1e-08 31.8 0.1 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.12 OQS05985.1 - 3.7e-10 39.6 0.0 4.6e-10 39.3 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 OQS05985.1 - 2.2e-05 24.5 0.0 3.3e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.18 OQS05985.1 - 0.0062 15.9 0.0 0.01 15.1 0.0 1.3 1 0 0 1 1 1 1 6-phosphofructo-2-kinase RsgA_GTPase PF03193.16 OQS05985.1 - 0.036 14.0 0.0 0.34 10.8 0.0 2.0 2 0 0 2 2 2 0 RsgA GTPase Arf PF00025.21 OQS05986.1 - 2.7e-46 157.2 0.1 3.2e-46 157.0 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 OQS05986.1 - 1.5e-09 37.6 0.1 1.8e-09 37.3 0.1 1.0 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 OQS05986.1 - 1.1e-08 34.8 0.1 1.3e-08 34.5 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Roc PF08477.13 OQS05986.1 - 9.1e-08 32.3 0.1 1.3e-07 31.8 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 OQS05986.1 - 1.3e-06 28.1 0.0 1.6e-06 27.8 0.0 1.1 1 0 0 1 1 1 1 Ras family MMR_HSR1 PF01926.23 OQS05986.1 - 2e-05 24.7 0.1 3.3e-05 23.9 0.1 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase G-alpha PF00503.20 OQS05986.1 - 0.00021 20.6 1.6 0.018 14.2 0.5 2.3 1 1 1 2 2 2 1 G-protein alpha subunit AAA_5 PF07728.14 OQS05986.1 - 0.00033 20.7 0.9 0.0045 17.0 0.9 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 OQS05986.1 - 0.0012 19.0 0.1 0.002 18.3 0.1 1.4 1 1 0 1 1 1 1 AAA domain Septin PF00735.18 OQS05986.1 - 0.0055 16.0 3.2 0.32 10.2 3.2 2.2 1 1 0 1 1 1 1 Septin AAA_14 PF13173.6 OQS05986.1 - 0.0065 16.5 0.1 0.0093 16.0 0.1 1.2 1 0 0 1 1 1 1 AAA domain cobW PF02492.19 OQS05986.1 - 0.0086 15.7 1.6 0.68 9.5 0.1 2.1 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain RsgA_GTPase PF03193.16 OQS05986.1 - 0.02 14.8 0.1 5.2 7.0 0.0 2.1 2 0 0 2 2 2 0 RsgA GTPase AAA_25 PF13481.6 OQS05986.1 - 0.022 14.4 0.5 0.34 10.4 0.0 2.5 2 1 1 3 3 3 0 AAA domain NB-ARC PF00931.22 OQS05986.1 - 0.023 13.9 0.3 0.068 12.3 0.3 1.8 1 1 0 1 1 1 0 NB-ARC domain AAA_24 PF13479.6 OQS05986.1 - 0.052 13.3 0.3 0.078 12.7 0.3 1.5 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 OQS05986.1 - 0.059 13.8 0.1 0.091 13.2 0.1 1.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 OQS05986.1 - 0.085 12.4 0.1 0.13 11.8 0.1 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region NACHT PF05729.12 OQS05986.1 - 0.091 12.7 0.7 1.2 9.0 0.7 2.1 1 1 0 1 1 1 0 NACHT domain PduV-EutP PF10662.9 OQS05986.1 - 0.1 12.3 0.4 0.19 11.5 0.4 1.6 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation ABC_tran PF00005.27 OQS05986.1 - 0.12 12.8 0.2 0.18 12.3 0.2 1.5 1 1 0 1 1 1 0 ABC transporter TIR_3 PF18567.1 OQS05986.1 - 0.13 12.2 0.1 0.31 11.0 0.0 1.5 2 0 0 2 2 2 0 Toll/interleukin-1 receptor domain Arf PF00025.21 OQS05987.1 - 2.2e-19 69.6 0.0 2.4e-19 69.4 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Arf PF00025.21 OQS05988.1 - 8.5e-64 214.2 0.7 9.7e-64 214.0 0.7 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 OQS05988.1 - 8.7e-15 55.0 0.0 1.2e-14 54.6 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 OQS05988.1 - 9.6e-15 54.5 0.1 1.1e-14 54.2 0.1 1.0 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.22 OQS05988.1 - 3.8e-13 49.3 0.1 4.4e-13 49.1 0.1 1.0 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 OQS05988.1 - 7.6e-12 45.1 0.0 9.4e-12 44.8 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 OQS05988.1 - 1.4e-06 28.4 0.0 2e-06 27.8 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase G-alpha PF00503.20 OQS05988.1 - 1.4e-05 24.5 0.2 0.025 13.8 0.1 2.4 1 1 1 2 2 2 2 G-protein alpha subunit FeoB_N PF02421.18 OQS05988.1 - 0.0014 18.2 1.4 0.0025 17.3 1.4 1.5 1 1 0 1 1 1 1 Ferrous iron transport protein B AAA_33 PF13671.6 OQS05988.1 - 0.037 14.2 0.1 0.082 13.1 0.1 1.8 1 1 0 1 1 1 0 AAA domain 6PF2K PF01591.18 OQS05988.1 - 0.089 12.1 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 6-phosphofructo-2-kinase Ank_4 PF13637.6 OQS05989.1 - 1.1e-10 41.8 0.1 0.00012 22.5 0.1 3.1 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 OQS05989.1 - 3e-09 37.0 0.3 0.0078 16.5 0.0 3.1 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 OQS05989.1 - 2.3e-07 31.3 0.2 0.00023 21.7 0.0 2.1 1 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OQS05989.1 - 0.014 15.9 0.0 7.3 7.5 0.0 3.7 4 0 0 4 4 4 0 Ankyrin repeat Peptidase_C12 PF01088.21 OQS05989.1 - 0.052 13.3 0.0 0.068 12.9 0.0 1.2 1 0 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase, family 1 DUF5049 PF16468.5 OQS05989.1 - 0.053 13.4 0.1 4 7.4 0.0 2.5 2 1 1 3 3 3 0 Domain of unknown function (DUF5049) Aminotran_1_2 PF00155.21 OQS05990.1 - 8.4e-58 196.3 0.0 1.2e-57 195.8 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II PDT PF00800.18 OQS05990.1 - 1.5e-26 93.4 0.0 3.1e-26 92.3 0.0 1.6 1 0 0 1 1 1 1 Prephenate dehydratase Aminotran_MocR PF12897.7 OQS05990.1 - 0.0023 16.8 0.0 0.0037 16.1 0.0 1.3 1 0 0 1 1 1 1 Alanine-glyoxylate amino-transferase OKR_DC_1 PF01276.20 OQS05990.1 - 0.0056 15.5 0.0 0.013 14.3 0.0 1.5 2 0 0 2 2 2 1 Orn/Lys/Arg decarboxylase, major domain DegT_DnrJ_EryC1 PF01041.17 OQS05990.1 - 0.0064 15.8 0.0 0.015 14.6 0.0 1.6 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family SRP54 PF00448.22 OQS05992.1 - 4.8e-75 251.5 0.3 7.8e-75 250.8 0.3 1.3 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SRP_SPB PF02978.19 OQS05992.1 - 4.2e-27 94.7 0.4 4.2e-27 94.7 0.4 3.6 3 0 0 3 3 3 1 Signal peptide binding domain SRP54_N PF02881.19 OQS05992.1 - 9e-17 61.1 0.3 1.7e-16 60.1 0.3 1.5 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain AAA_33 PF13671.6 OQS05992.1 - 4.1e-06 27.0 0.0 8e-06 26.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 OQS05992.1 - 3e-05 24.5 0.0 0.00011 22.7 0.0 1.8 1 1 1 2 2 2 1 AAA ATPase domain cobW PF02492.19 OQS05992.1 - 6.8e-05 22.5 0.3 0.00074 19.1 0.3 2.2 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.6 OQS05992.1 - 0.00016 21.5 0.0 0.00038 20.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 OQS05992.1 - 0.0011 19.4 0.0 0.009 16.3 0.0 2.3 2 0 0 2 2 2 1 AAA domain MeaB PF03308.16 OQS05992.1 - 0.0042 16.1 0.0 0.028 13.4 0.0 2.3 1 1 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB Zeta_toxin PF06414.12 OQS05992.1 - 0.0051 16.1 0.1 0.0097 15.2 0.1 1.4 1 0 0 1 1 1 1 Zeta toxin SRPRB PF09439.10 OQS05992.1 - 0.0063 16.0 0.5 3.4 7.1 0.1 2.6 1 1 1 2 2 2 2 Signal recognition particle receptor beta subunit CbiA PF01656.23 OQS05992.1 - 0.0069 16.4 0.0 0.021 14.9 0.0 1.7 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain APS_kinase PF01583.20 OQS05992.1 - 0.016 15.1 0.0 0.034 14.0 0.0 1.5 1 0 0 1 1 1 0 Adenylylsulphate kinase ResIII PF04851.15 OQS05992.1 - 0.016 15.2 0.4 0.034 14.1 0.4 1.5 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_7 PF12775.7 OQS05992.1 - 0.022 14.3 0.1 0.058 12.9 0.1 1.7 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_17 PF13207.6 OQS05992.1 - 0.028 14.9 3.4 0.039 14.4 0.1 2.7 3 1 0 3 3 2 0 AAA domain MMR_HSR1 PF01926.23 OQS05992.1 - 0.034 14.2 0.8 0.34 11.0 0.6 2.6 2 1 0 2 2 2 0 50S ribosome-binding GTPase AAA_22 PF13401.6 OQS05992.1 - 0.041 14.2 0.5 0.15 12.3 0.1 2.2 2 1 0 2 2 2 0 AAA domain MobB PF03205.14 OQS05992.1 - 0.048 13.6 0.0 0.11 12.3 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Repressor_Mnt PF11423.8 OQS05992.1 - 0.087 12.6 0.1 1.1 9.0 0.1 2.6 2 0 0 2 2 2 0 Regulatory protein Mnt AAA_28 PF13521.6 OQS05992.1 - 0.11 12.7 0.0 0.19 11.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain DUF2209 PF09974.9 OQS05992.1 - 0.13 12.6 0.4 0.31 11.4 0.4 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2209) DNA_pol3_chi PF04364.13 OQS05992.1 - 0.15 12.2 0.0 0.38 10.9 0.0 1.6 1 1 0 1 1 1 0 DNA polymerase III chi subunit, HolC zf-RING_UBOX PF13445.6 OQS05993.1 - 7.7e-10 38.6 4.8 9.4e-10 38.4 3.3 2.0 1 1 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 OQS05993.1 - 1.6e-09 37.4 6.5 5.9e-09 35.6 6.7 1.9 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 OQS05993.1 - 2.1e-08 34.2 7.3 5.3e-08 32.9 7.3 1.8 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.25 OQS05993.1 - 3.3e-08 33.3 6.6 6.4e-08 32.4 6.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 OQS05993.1 - 1.6e-07 31.5 8.4 3.1e-07 30.6 8.4 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 OQS05993.1 - 3.6e-07 30.0 5.0 8.8e-07 28.8 5.0 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 OQS05993.1 - 1e-06 28.5 5.4 1.9e-06 27.6 5.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.6 OQS05993.1 - 0.00018 21.3 2.7 0.00045 20.0 2.7 1.6 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-Nse PF11789.8 OQS05993.1 - 0.00035 20.3 3.0 0.0008 19.2 3.0 1.7 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit Prok-RING_4 PF14447.6 OQS05993.1 - 0.00063 19.5 5.5 0.0027 17.5 5.5 2.0 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-rbx1 PF12678.7 OQS05993.1 - 0.072 13.4 7.3 0.17 12.2 7.3 1.7 1 1 0 1 1 1 0 RING-H2 zinc finger domain DUF3824 PF12868.7 OQS05993.1 - 0.082 13.6 0.5 0.19 12.4 0.5 1.5 1 0 0 1 1 1 0 Domain of unknwon function (DUF3824) zf-MIZ PF02891.20 OQS05993.1 - 0.21 11.4 7.9 0.41 10.4 7.9 1.5 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger zf-ANAPC11 PF12861.7 OQS05993.1 - 0.23 11.5 4.6 0.81 9.8 4.6 1.9 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_11 PF17123.5 OQS05993.1 - 0.87 9.4 7.8 0.85 9.4 4.5 2.5 2 0 0 2 2 2 0 RING-like zinc finger DUF3886 PF13025.6 OQS05993.1 - 3.9 7.7 7.3 1.5 9.0 2.9 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3886) Peptidase_M13_N PF05649.13 OQS05994.1 - 8.5e-73 246.2 0.0 1.2e-72 245.7 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13 PF01431.21 OQS05994.1 - 2.1e-65 220.2 0.0 3.8e-65 219.3 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13_N PF05649.13 OQS05997.1 - 3.7e-74 250.7 0.0 4.8e-74 250.3 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13 PF01431.21 OQS05997.1 - 1.8e-69 233.5 0.0 3.3e-69 232.6 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M13 FYVE PF01363.21 OQS05998.1 - 0.00038 20.6 8.1 0.00074 19.6 8.1 1.4 1 0 0 1 1 1 1 FYVE zinc finger START PF01852.19 OQS05998.1 - 0.01 15.2 0.0 0.054 12.9 0.0 2.0 1 1 0 1 1 1 0 START domain FYVE_2 PF02318.16 OQS05998.1 - 0.03 14.5 5.5 0.07 13.3 5.5 1.6 1 0 0 1 1 1 0 FYVE-type zinc finger Siva PF05458.12 OQS05998.1 - 0.057 13.1 2.7 0.12 12.1 2.7 1.4 1 0 0 1 1 1 0 Cd27 binding protein (Siva) IBR PF01485.21 OQS05998.1 - 5.6 7.3 9.7 49 4.3 0.1 2.4 1 1 1 2 2 2 0 IBR domain, a half RING-finger domain zf-piccolo PF05715.13 OQS05998.1 - 6.2 7.1 10.6 13 6.0 10.6 1.5 1 0 0 1 1 1 0 Piccolo Zn-finger SGL PF08450.12 OQS05999.1 - 1e-11 44.9 0.1 1.7e-11 44.2 0.1 1.4 1 0 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region NHL PF01436.21 OQS05999.1 - 2.7e-05 24.0 0.3 0.05 13.7 0.0 3.6 3 0 0 3 3 3 2 NHL repeat SBBP PF06739.11 OQS05999.1 - 0.035 14.1 0.1 0.035 14.1 0.1 3.8 4 0 0 4 4 4 0 Beta-propeller repeat IQ PF00612.27 OQS06000.1 - 0.0001 21.8 1.2 0.00028 20.4 0.5 2.2 2 0 0 2 2 2 1 IQ calmodulin-binding motif Zn_ribbon_17 PF17120.5 OQS06000.1 - 0.0044 16.6 2.7 0.0044 16.6 2.7 2.1 2 0 0 2 2 2 1 Zinc-ribbon, C4HC2 type PH PF00169.29 OQS06000.1 - 0.014 15.9 0.5 0.16 12.5 0.1 2.9 4 0 0 4 4 4 0 PH domain PH_13 PF16652.5 OQS06000.1 - 0.014 15.2 0.0 0.17 11.7 0.0 2.5 2 0 0 2 2 2 0 Pleckstrin homology domain C1_2 PF03107.16 OQS06000.1 - 0.017 15.4 2.5 0.23 11.8 0.6 3.0 2 0 0 2 2 2 0 C1 domain PHD_2 PF13831.6 OQS06000.1 - 0.11 12.0 3.1 0.28 10.8 0.2 2.6 2 0 0 2 2 2 0 PHD-finger Zf_RING PF16744.5 OQS06000.1 - 1.6 8.9 5.4 4 7.6 5.4 1.6 1 0 0 1 1 1 0 KIAA1045 RING finger GFO_IDH_MocA PF01408.22 OQS06002.1 - 1.2e-19 71.3 0.1 2.6e-19 70.2 0.1 1.6 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Shikimate_DH PF01488.20 OQS06002.1 - 0.0004 20.5 0.1 0.0014 18.7 0.0 1.9 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase DapB_N PF01113.20 OQS06002.1 - 0.0017 18.4 0.1 0.0052 16.9 0.1 1.9 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus GFO_IDH_MocA_C PF02894.17 OQS06002.1 - 0.13 12.2 0.0 0.3 11.1 0.0 1.7 1 0 0 1 1 1 0 Oxidoreductase family, C-terminal alpha/beta domain zf-C2H2 PF00096.26 OQS06003.1 - 2.6e-19 68.5 24.9 1.2e-05 25.5 0.9 4.3 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 OQS06003.1 - 1.4e-17 63.2 23.6 4.2e-06 26.9 1.6 5.2 5 0 0 5 5 5 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 OQS06003.1 - 9.4e-14 50.9 23.3 0.0059 17.3 0.9 4.3 4 0 0 4 4 4 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 OQS06003.1 - 9.3e-05 22.6 15.3 0.14 12.4 0.2 4.3 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding Tyr-DNA_phospho PF06087.12 OQS06003.1 - 0.00041 19.4 0.1 0.00058 18.9 0.1 1.1 1 0 0 1 1 1 1 Tyrosyl-DNA phosphodiesterase zf-C2H2_8 PF15909.5 OQS06003.1 - 0.0016 18.7 9.6 0.02 15.2 6.1 2.5 1 1 1 2 2 2 1 C2H2-type zinc ribbon zf-C2H2_aberr PF17017.5 OQS06003.1 - 0.0017 18.5 6.8 0.21 11.7 0.2 3.1 1 1 1 3 3 3 2 Aberrant zinc-finger zf-C2H2_11 PF16622.5 OQS06003.1 - 0.0036 17.0 9.1 0.08 12.7 0.1 3.0 3 0 0 3 3 3 2 zinc-finger C2H2-type zf-met PF12874.7 OQS06003.1 - 0.0097 16.3 13.4 0.056 13.9 0.8 4.3 4 0 0 4 4 4 1 Zinc-finger of C2H2 type DUF4764 PF15961.5 OQS06003.1 - 0.016 13.9 1.8 0.023 13.4 1.6 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4764) zf-C2H2_6 PF13912.6 OQS06003.1 - 0.018 15.0 0.6 0.018 15.0 0.6 4.1 4 0 0 4 4 4 0 C2H2-type zinc finger FOXP-CC PF16159.5 OQS06003.1 - 0.03 14.9 13.0 0.82 10.3 2.5 4.2 2 1 3 5 5 5 0 FOXP coiled-coil domain GAGA PF09237.11 OQS06003.1 - 0.056 13.2 4.0 6.3 6.7 0.1 3.1 3 1 0 3 3 3 0 GAGA factor zf-TRAF PF02176.18 OQS06003.1 - 0.47 11.2 11.2 4.4 8.1 2.9 2.5 2 0 0 2 2 2 0 TRAF-type zinc finger zf_UBZ PF18439.1 OQS06003.1 - 0.62 9.7 5.1 5.2 6.7 0.0 3.5 4 0 0 4 4 4 0 Ubiquitin-Binding Zinc Finger zf-H2C2_5 PF13909.6 OQS06003.1 - 0.82 9.5 12.8 13 5.7 0.1 4.3 4 0 0 4 4 4 0 C2H2-type zinc-finger domain zf-C2H2_9 PF16293.5 OQS06003.1 - 1.7 8.5 5.1 21 5.1 0.0 3.2 4 0 0 4 4 4 0 C2H2 type zinc-finger (1 copy) zf-C2H2_2 PF12756.7 OQS06003.1 - 2.1 8.7 6.7 1 9.7 1.9 2.3 1 1 0 2 2 2 0 C2H2 type zinc-finger (2 copies) zf_ZIC PF18366.1 OQS06003.1 - 5.4 7.2 10.2 6.1 7.0 0.1 4.0 4 0 0 4 4 4 0 Zic proteins zinc finger domain Glyco_hydro_17 PF00332.18 OQS06004.1 - 6.6e-07 29.2 5.4 1e-05 25.3 5.4 2.1 1 1 0 1 1 1 1 Glycosyl hydrolases family 17 Pro-kuma_activ PF09286.11 OQS06004.1 - 0.068 13.5 0.0 0.18 12.1 0.0 1.6 1 1 0 1 1 1 0 Pro-kumamolisin, activation domain Med3 PF11593.8 OQS06004.1 - 0.12 11.5 4.6 0.19 10.9 4.6 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal 30K_MP_core PF17644.1 OQS06004.1 - 0.14 12.0 0.5 0.45 10.4 0.1 2.0 2 0 0 2 2 2 0 Core domain of 30K viral movement proteins Meckelin PF09773.9 OQS06005.1 - 1.5e-165 552.6 18.7 1.5e-165 552.6 18.7 1.4 2 0 0 2 2 2 1 Meckelin (Transmembrane protein 67) PRKCSH PF07915.13 OQS06006.1 - 1.9e-07 32.0 7.1 3.8e-07 31.0 5.9 2.2 2 1 0 2 2 2 1 Glucosidase II beta subunit-like protein Yippee-Mis18 PF03226.14 OQS06006.1 - 9.9e-07 28.9 0.0 0.0025 18.0 0.0 2.7 2 0 0 2 2 2 2 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly PRKCSH_1 PF13015.6 OQS06006.1 - 0.0006 19.5 3.7 0.38 10.4 0.4 2.2 2 0 0 2 2 2 2 Glucosidase II beta subunit-like protein DUF2039 PF10217.9 OQS06006.1 - 0.00092 19.5 1.7 0.4 11.1 0.2 3.0 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2039) DUF3932 PF13068.6 OQS06006.1 - 0.11 12.9 0.0 0.65 10.3 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3932) zinc_ribbon_10 PF10058.9 OQS06006.1 - 1.1 9.0 3.9 5.9 6.7 0.0 3.1 3 0 0 3 3 3 0 Predicted integral membrane zinc-ribbon metal-binding protein PAN_4 PF14295.6 OQS06007.1 - 2.1e-28 98.0 51.3 2.6e-10 40.0 4.3 5.5 5 0 0 5 5 5 4 PAN domain PAN_1 PF00024.26 OQS06007.1 - 1.4e-18 66.6 31.2 0.0002 21.3 7.0 4.7 2 1 3 5 5 5 4 PAN domain CAP PF00188.26 OQS06007.1 - 2.3e-12 47.8 5.9 2.3e-12 47.8 5.9 3.0 3 1 1 4 4 4 1 Cysteine-rich secretory protein family PAN_3 PF08277.12 OQS06007.1 - 0.00011 21.9 39.5 0.023 14.5 5.4 5.6 5 0 0 5 5 5 3 PAN-like domain U71 PF17474.2 OQS06007.1 - 0.0047 16.8 2.6 0.046 13.7 0.0 3.7 4 1 1 5 5 5 1 Tegument protein UL11 homolog Peptidase_C42 PF05533.12 OQS06007.1 - 0.021 14.8 0.6 13 5.9 0.0 3.0 3 0 0 3 3 3 0 Beet yellows virus-type papain-like endopeptidase C42 PT PF04886.12 OQS06008.1 - 0.014 15.0 37.2 0.014 15.0 37.2 5.6 4 2 0 4 4 4 0 PT repeat Cation_efflux PF01545.21 OQS06009.1 - 4.1e-44 150.7 35.8 7.8e-23 81.2 14.1 2.1 2 0 0 2 2 2 2 Cation efflux family ZT_dimer PF16916.5 OQS06009.1 - 6.3e-20 71.1 9.9 9.8e-10 38.4 1.1 2.4 2 0 0 2 2 2 2 Dimerisation domain of Zinc Transporter DUF2167 PF09935.9 OQS06009.1 - 0.0011 18.2 0.8 0.04 13.1 0.1 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF2167) Pkinase_Tyr PF07714.17 OQS06010.1 - 0.0016 17.8 0.0 0.0028 17.0 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OQS06010.1 - 0.033 13.6 0.0 0.049 13.0 0.0 1.2 1 0 0 1 1 1 0 Protein kinase domain Ank_4 PF13637.6 OQS06011.1 - 3.8e-21 75.2 5.1 2.7e-09 37.4 0.2 3.2 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 OQS06011.1 - 9.6e-18 64.0 10.9 3.3e-09 36.8 0.7 3.0 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 OQS06011.1 - 1.1e-17 64.4 1.8 1.9e-16 60.4 0.2 2.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 OQS06011.1 - 3.3e-12 46.3 1.8 2.7e-05 24.4 0.1 4.3 4 0 0 4 4 4 2 Ankyrin repeat Ank_3 PF13606.6 OQS06011.1 - 6.4e-09 35.3 0.4 0.00045 20.5 0.1 3.6 3 0 0 3 3 3 2 Ankyrin repeat Rax2 PF12768.7 OQS06011.1 - 0.12 11.8 0.0 0.18 11.2 0.0 1.2 1 0 0 1 1 1 0 Cortical protein marker for cell polarity R3H PF01424.22 OQS06012.1 - 4.4e-07 29.8 0.3 2.4e-06 27.4 0.1 2.2 2 0 0 2 2 2 1 R3H domain R3H-assoc PF13902.6 OQS06012.1 - 5.5e-05 23.6 6.1 9.4e-05 22.8 6.1 1.4 1 0 0 1 1 1 1 R3H-associated N-terminal domain EF-hand_1 PF00036.32 OQS06013.1 - 1e-24 84.2 9.4 2.5e-06 26.6 0.4 4.5 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.6 OQS06013.1 - 1.1e-21 74.9 8.3 0.00029 20.5 0.0 4.7 4 0 0 4 4 4 4 EF-hand domain EF-hand_7 PF13499.6 OQS06013.1 - 2.3e-20 72.8 7.7 2.7e-12 47.0 0.2 3.3 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.6 OQS06013.1 - 2.1e-19 68.1 7.0 3.8e-05 23.0 0.0 4.4 4 0 0 4 4 4 4 EF hand Acyltransferase PF01553.21 OQS06013.1 - 3.5e-15 55.8 0.0 6.8e-15 54.9 0.0 1.5 1 0 0 1 1 1 1 Acyltransferase EF-hand_8 PF13833.6 OQS06013.1 - 3.8e-15 55.5 9.9 1.4e-06 28.0 0.2 4.5 3 1 1 4 4 4 4 EF-hand domain pair SPARC_Ca_bdg PF10591.9 OQS06013.1 - 0.00034 20.9 0.1 1.4 9.3 0.0 2.4 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 OQS06013.1 - 0.00065 19.6 2.2 1.2 9.2 0.4 3.0 2 1 1 3 3 3 2 Cytoskeletal-regulatory complex EF hand Methyltransf_30 PF05430.11 OQS06013.1 - 0.034 14.0 0.0 0.11 12.4 0.0 1.8 2 0 0 2 2 2 0 S-adenosyl-L-methionine-dependent methyltransferase TerB PF05099.13 OQS06013.1 - 0.13 12.3 0.0 0.3 11.0 0.0 1.6 1 0 0 1 1 1 0 Tellurite resistance protein TerB TMEM187 PF15100.6 OQS06013.1 - 0.14 11.7 0.0 0.31 10.6 0.0 1.5 2 0 0 2 2 2 0 TMEM187 protein family FYVE_2 PF02318.16 OQS06014.1 - 1.4e-05 25.3 5.2 3e-05 24.2 5.2 1.5 1 0 0 1 1 1 1 FYVE-type zinc finger FYVE PF01363.21 OQS06014.1 - 0.0096 16.0 10.3 0.026 14.7 10.3 1.7 1 0 0 1 1 1 1 FYVE zinc finger PHF5 PF03660.14 OQS06014.1 - 0.16 12.2 5.7 0.2 11.9 5.0 1.5 1 1 0 1 1 1 0 PHF5-like protein Orai-1 PF07856.12 OQS06015.1 - 2.6e-35 121.6 5.6 3.7e-35 121.1 5.6 1.1 1 0 0 1 1 1 1 Mediator of CRAC channel activity DUF417 PF04224.12 OQS06015.1 - 0.065 12.8 1.4 0.14 11.7 0.3 1.9 2 0 0 2 2 2 0 Protein of unknown function, DUF417 SK_channel PF03530.14 OQS06015.1 - 0.12 12.4 2.4 0.24 11.4 0.4 2.1 2 0 0 2 2 2 0 Calcium-activated SK potassium channel Exonuc_VII_L PF02601.15 OQS06015.1 - 0.14 11.7 0.2 0.24 10.9 0.2 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit Jiraiya PF15038.6 OQS06015.1 - 6 6.3 14.3 1e+02 2.3 14.3 2.6 1 1 0 1 1 1 0 Jiraiya Thioredoxin PF00085.20 OQS06016.1 - 4.5e-13 49.1 0.0 7.3e-13 48.4 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_9 PF14595.6 OQS06016.1 - 0.012 15.4 0.0 0.018 14.8 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin AMP-binding PF00501.28 OQS06017.1 - 0.015 13.9 0.0 0.015 13.9 0.0 1.0 1 0 0 1 1 1 0 AMP-binding enzyme COPI_assoc PF08507.10 OQS06018.1 - 0.001 19.1 12.5 0.0016 18.5 12.5 1.3 1 0 0 1 1 1 1 COPI associated protein CD20 PF04103.15 OQS06018.1 - 0.096 12.8 0.8 0.096 12.8 0.8 2.2 2 1 0 2 2 2 0 CD20-like family YtpI PF14007.6 OQS06018.1 - 0.16 12.2 5.0 0.12 12.5 2.7 2.1 1 1 1 2 2 2 0 YtpI-like protein VKOR PF07884.14 OQS06018.1 - 3.3 7.9 10.7 10 6.4 10.7 1.7 1 1 0 1 1 1 0 Vitamin K epoxide reductase family DUF308 PF03729.13 OQS06018.1 - 8.8 6.7 18.2 43 4.5 0.1 2.9 2 1 0 2 2 2 0 Short repeat of unknown function (DUF308) VWA PF00092.28 OQS06019.1 - 5.7e-11 43.0 0.1 1e-09 38.9 0.0 2.8 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA_2 PF13519.6 OQS06019.1 - 4.7e-08 33.6 0.0 5.7e-07 30.2 0.0 2.9 3 0 0 3 3 3 1 von Willebrand factor type A domain GBP PF02263.19 OQS06019.1 - 6.4e-07 28.9 0.7 1.6e-05 24.3 0.1 2.6 2 0 0 2 2 2 1 Guanylate-binding protein, N-terminal domain RHD3 PF05879.12 OQS06019.1 - 8.1e-05 21.0 0.1 0.00017 19.9 0.1 1.5 1 0 0 1 1 1 1 Root hair defective 3 GTP-binding protein (RHD3) Dynamin_N PF00350.23 OQS06019.1 - 0.0088 16.1 0.0 0.032 14.3 0.0 1.9 1 0 0 1 1 1 1 Dynamin family TAXi_N PF14543.6 OQS06020.1 - 1.3e-23 84.2 6.1 1.9e-23 83.6 6.1 1.3 1 0 0 1 1 1 1 Xylanase inhibitor N-terminal Asp PF00026.23 OQS06020.1 - 1.6e-21 77.1 0.6 2.9e-20 73.0 0.6 2.1 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.6 OQS06020.1 - 1e-09 38.4 0.0 2e-09 37.4 0.0 1.5 1 0 0 1 1 1 1 Xylanase inhibitor C-terminal TMEM154 PF15102.6 OQS06020.1 - 0.12 12.3 0.1 0.22 11.4 0.1 1.4 1 0 0 1 1 1 0 TMEM154 protein family ANAPC5 PF12862.7 OQS06021.1 - 9.9e-19 67.2 3.8 9.9e-19 67.2 3.8 2.3 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 5 SPK PF04435.18 OQS06021.1 - 0.15 12.4 0.0 0.38 11.2 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF545) A_deaminase PF00962.22 OQS06023.1 - 1.1e-54 185.9 0.1 1.2e-32 113.5 0.1 2.0 2 0 0 2 2 2 2 Adenosine/AMP deaminase Asp PF00026.23 OQS06024.1 - 5.4e-22 78.6 2.0 1.1e-21 77.6 2.0 1.5 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 OQS06024.1 - 1.1e-21 77.9 4.0 2.2e-21 76.9 4.0 1.6 1 0 0 1 1 1 1 Xylanase inhibitor N-terminal TAXi_C PF14541.6 OQS06024.1 - 1e-09 38.4 0.0 5e-09 36.1 0.0 2.1 2 0 0 2 2 2 1 Xylanase inhibitor C-terminal TMEM51 PF15345.6 OQS06024.1 - 0.04 13.8 0.4 0.2 11.5 0.0 2.1 2 0 0 2 2 2 0 Transmembrane protein 51 Peptidase_M3 PF01432.20 OQS06024.1 - 0.077 12.2 0.4 0.31 10.2 0.4 1.9 2 0 0 2 2 2 0 Peptidase family M3 PetM PF08041.11 OQS06024.1 - 8.6 6.0 5.9 19 4.9 5.9 1.6 1 0 0 1 1 1 0 PetM family of cytochrome b6f complex subunit 7 F-box_4 PF15966.5 OQS06027.1 - 0.074 12.9 2.3 45 4.0 0.0 4.3 4 0 0 4 4 4 0 F-box Rubredoxin PF00301.20 OQS06027.1 - 0.62 10.1 10.1 4.6 7.3 0.1 4.6 5 0 0 5 5 5 0 Rubredoxin zf-BED PF02892.15 OQS06027.1 - 1.5 8.9 27.6 4.6 7.4 0.5 5.6 4 1 0 4 4 4 0 BED zinc finger zinc_ribbon_4 PF13717.6 OQS06027.1 - 7.3 6.6 18.0 10 6.1 0.4 4.4 4 0 0 4 4 4 0 zinc-ribbon domain Asp PF00026.23 OQS06028.1 - 2.1e-27 96.4 0.4 5.9e-27 94.9 0.4 1.7 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 OQS06028.1 - 2.1e-24 86.7 3.5 4.2e-24 85.8 3.5 1.5 1 0 0 1 1 1 1 Xylanase inhibitor N-terminal TAXi_C PF14541.6 OQS06028.1 - 1.4e-05 25.0 0.0 0.0011 18.7 0.0 3.3 3 1 0 3 3 3 1 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.6 OQS06028.1 - 0.15 12.7 0.0 9.3 7.0 0.0 2.6 2 0 0 2 2 2 0 Aspartyl protease Pkinase PF00069.25 OQS06029.1 - 4.8e-37 127.7 0.1 6.9e-37 127.2 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQS06029.1 - 5.1e-36 124.3 0.0 6.7e-36 123.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OQS06029.1 - 0.00098 18.0 0.4 0.0019 17.1 0.2 1.5 2 0 0 2 2 2 1 Fungal protein kinase DZR PF12773.7 OQS06029.1 - 0.0013 18.7 4.7 0.0025 17.8 4.7 1.5 1 0 0 1 1 1 1 Double zinc ribbon Cytochrom_c3_2 PF14537.6 OQS06029.1 - 0.0015 18.9 4.8 0.0033 17.9 4.8 1.6 1 0 0 1 1 1 1 Cytochrome c3 Kdo PF06293.14 OQS06029.1 - 0.031 13.6 0.0 0.049 13.0 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Med27 PF11571.8 OQS06029.1 - 3.8 7.9 8.6 0.76 10.2 0.5 2.5 1 1 1 2 2 2 0 Mediator complex subunit 27 UPF0640 PF15114.6 OQS06031.1 - 0.065 13.0 0.0 0.078 12.8 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family UPF0640 Telomerase_RBD PF12009.8 OQS06032.1 - 4.9e-20 72.0 3.5 2e-19 70.0 3.5 2.1 1 0 0 1 1 1 1 Telomerase ribonucleoprotein complex - RNA binding domain RVT_1 PF00078.27 OQS06032.1 - 1.1e-16 61.1 0.6 6.8e-13 48.7 0.1 2.9 3 0 0 3 3 3 2 Reverse transcriptase (RNA-dependent DNA polymerase) TrfA PF07042.11 OQS06033.1 - 0.0052 15.9 0.0 0.0052 15.9 0.0 1.0 1 0 0 1 1 1 1 TrfA protein Ufm1 PF03671.14 OQS06034.1 - 5.1e-42 141.8 0.0 5.7e-42 141.7 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin fold modifier 1 protein PTR2 PF00854.21 OQS06035.1 - 3.3e-58 197.4 12.0 1.9e-57 194.9 12.0 2.0 1 1 0 1 1 1 1 POT family Chordopox_A13L PF05961.11 OQS06035.1 - 0.0044 17.2 0.1 0.049 13.9 0.0 2.7 2 0 0 2 2 2 1 Chordopoxvirus A13L protein DUF4293 PF14126.6 OQS06035.1 - 3 8.1 10.2 0.16 12.2 0.4 2.9 2 2 0 2 2 2 0 Domain of unknown function (DUF4293) EamA PF00892.20 OQS06035.1 - 3.1 8.0 18.7 0.22 11.7 0.5 4.4 3 1 1 4 4 4 0 EamA-like transporter family PARP PF00644.20 OQS06037.1 - 5.2e-21 75.1 0.0 7.7e-21 74.6 0.0 1.3 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain Abhydrolase_3 PF07859.13 OQS06037.1 - 1.5e-20 73.9 0.0 3.5e-20 72.8 0.0 1.6 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 OQS06037.1 - 5.4e-10 39.1 0.0 3.5e-09 36.5 0.0 2.1 1 1 0 1 1 1 1 Prolyl oligopeptidase family COesterase PF00135.28 OQS06037.1 - 0.0042 16.0 0.0 0.012 14.5 0.0 1.6 1 1 0 1 1 1 1 Carboxylesterase family Hydrolase_4 PF12146.8 OQS06037.1 - 0.015 14.5 0.0 0.29 10.4 0.0 2.4 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 OQS06037.1 - 0.019 14.6 0.0 0.16 11.6 0.0 2.1 1 1 1 2 2 2 0 alpha/beta hydrolase fold DASH_Dad3 PF08656.10 OQS06037.1 - 0.02 14.9 1.0 0.071 13.2 0.1 2.2 1 1 1 2 2 2 0 DASH complex subunit Dad3 Abhydrolase_4 PF08386.10 OQS06037.1 - 0.046 13.8 0.0 0.11 12.6 0.0 1.6 1 0 0 1 1 1 0 TAP-like protein Abhydrolase_6 PF12697.7 OQS06037.1 - 0.22 12.1 2.2 1.2 9.7 2.1 2.1 1 1 0 1 1 1 0 Alpha/beta hydrolase family Smim3 PF17307.2 OQS06038.1 - 0.34 10.5 3.8 0.89 9.1 3.8 1.6 1 0 0 1 1 1 0 Small integral membrane protein 3 PTR2 PF00854.21 OQS06039.1 - 4.3e-62 210.2 10.0 7.7e-62 209.4 10.0 1.4 1 0 0 1 1 1 1 POT family Nucleoporin_N PF08801.11 OQS06041.1 - 1e-55 189.3 0.2 1e-55 189.3 0.2 1.6 2 0 0 2 2 2 1 Nup133 N terminal like CdiI_4 PF18624.1 OQS06041.1 - 0.072 13.6 0.1 0.28 11.7 0.0 2.0 2 0 0 2 2 2 0 CDI immunity protein Retrotran_gag_2 PF14223.6 OQS06042.1 - 4e-17 62.2 0.5 5.5e-17 61.7 0.5 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type LLC1 PF14945.6 OQS06042.1 - 0.011 16.3 0.2 0.03 14.9 0.1 1.8 2 0 0 2 2 2 0 Normal lung function maintenance, Low in Lung Cancer 1 protein zf-CCHC PF00098.23 OQS06042.1 - 0.21 11.8 1.0 0.33 11.1 1.0 1.3 1 0 0 1 1 1 0 Zinc knuckle Mtc PF03820.17 OQS06043.1 - 2.6e-112 374.9 1.7 4.4e-112 374.2 1.7 1.3 1 0 0 1 1 1 1 Tricarboxylate carrier zf-MYND PF01753.18 OQS06043.1 - 0.00023 21.2 10.1 0.00023 21.2 10.1 2.2 2 0 0 2 2 2 1 MYND finger SET PF00856.28 OQS06043.1 - 0.011 16.2 0.5 0.046 14.1 0.0 2.3 4 0 0 4 4 4 0 SET domain Ank_2 PF12796.7 OQS06044.1 - 5.5e-26 91.0 23.0 2.7e-10 40.7 1.4 4.3 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQS06044.1 - 4.9e-23 81.2 16.4 1.5e-06 28.6 0.2 6.2 3 2 2 6 6 6 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 OQS06044.1 - 4.5e-19 68.3 13.1 6.2e-05 23.2 0.1 7.2 1 1 6 7 7 7 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQS06044.1 - 5.5e-14 50.9 12.0 0.13 12.9 0.0 9.2 7 2 2 9 9 9 3 Ankyrin repeat Ank PF00023.30 OQS06044.1 - 8.1e-06 26.1 14.0 0.16 12.4 0.0 7.0 4 2 3 7 7 7 2 Ankyrin repeat DUF5049 PF16468.5 OQS06044.1 - 6.8e-05 22.7 7.7 11 6.0 0.0 6.4 2 1 5 7 7 7 2 Domain of unknown function (DUF5049) CbtA_toxin PF06755.12 OQS06044.1 - 0.12 12.4 0.0 5.9 7.0 0.0 2.9 3 0 0 3 3 3 0 CbtA_toxin of type IV toxin-antitoxin system GMC_oxred_N PF00732.19 OQS06045.1 - 1e-34 120.3 0.0 3.1e-34 118.7 0.0 1.7 1 1 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 OQS06045.1 - 1.2e-22 81.0 0.1 2.4e-22 80.0 0.1 1.5 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 OQS06045.1 - 0.00086 18.5 0.0 0.0013 17.9 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain DEAD PF00270.29 OQS06046.1 - 1.6e-48 164.8 0.0 2.4e-48 164.2 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OQS06046.1 - 6.9e-32 110.1 0.0 1.8e-31 108.7 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 OQS06046.1 - 0.0032 17.5 0.0 0.0064 16.5 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit UTP25 PF06862.12 OQS06046.1 - 0.082 11.7 0.0 0.31 9.8 0.0 1.9 3 0 0 3 3 3 0 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 AAA_22 PF13401.6 OQS06046.1 - 0.11 12.8 0.0 0.84 9.9 0.0 2.2 2 0 0 2 2 2 0 AAA domain DAO PF01266.24 OQS06047.1 - 6.1e-54 183.9 0.0 8.5e-54 183.4 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO_C PF16901.5 OQS06047.1 - 1.6e-36 124.9 0.2 2.8e-36 124.2 0.2 1.4 1 0 0 1 1 1 1 C-terminal domain of alpha-glycerophosphate oxidase FAD_binding_2 PF00890.24 OQS06047.1 - 4.6e-08 32.6 1.0 2.6e-07 30.1 1.0 1.9 1 1 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 OQS06047.1 - 3.5e-07 29.9 0.4 4e-06 26.4 0.2 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 OQS06047.1 - 1e-05 25.0 0.5 3.9e-05 23.0 0.5 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 OQS06047.1 - 4.2e-05 22.4 1.1 7.3e-05 21.6 1.1 1.3 1 0 0 1 1 1 1 HI0933-like protein GIDA PF01134.22 OQS06047.1 - 0.00015 21.0 4.3 0.0018 17.5 2.0 2.3 2 0 0 2 2 2 1 Glucose inhibited division protein A NAD_binding_8 PF13450.6 OQS06047.1 - 0.00025 21.2 0.3 0.0024 18.1 0.5 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 OQS06047.1 - 0.00067 19.0 0.5 0.011 15.0 0.5 2.2 1 1 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 OQS06047.1 - 0.0018 17.6 0.1 0.0044 16.3 0.1 1.6 1 0 0 1 1 1 1 Thi4 family Pyr_redox_3 PF13738.6 OQS06047.1 - 0.0065 15.8 0.1 0.048 12.9 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Sacchrp_dh_NADP PF03435.18 OQS06047.1 - 0.0092 16.2 0.2 0.27 11.5 0.0 3.0 3 0 0 3 3 3 1 Saccharopine dehydrogenase NADP binding domain 3HCDH_N PF02737.18 OQS06047.1 - 0.023 14.6 0.1 0.054 13.4 0.1 1.7 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Lycopene_cycl PF05834.12 OQS06047.1 - 0.033 13.2 1.3 2.5 7.0 0.9 2.2 2 0 0 2 2 2 0 Lycopene cyclase protein DUF433 PF04255.14 OQS06047.1 - 0.041 13.8 0.2 14 5.6 0.1 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF433) Pyr_redox PF00070.27 OQS06047.1 - 0.042 14.4 0.6 0.042 14.4 0.6 3.3 4 0 0 4 4 4 0 Pyridine nucleotide-disulphide oxidoreductase Not3 PF04065.15 OQS06048.1 - 1.9e-84 282.7 16.0 2.4e-84 282.4 16.0 1.1 1 0 0 1 1 1 1 Not1 N-terminal domain, CCR4-Not complex component NOT2_3_5 PF04153.18 OQS06048.1 - 2.3e-42 144.2 7.1 7.8e-42 142.5 7.1 2.0 1 0 0 1 1 1 1 NOT2 / NOT3 / NOT5 family Syntaxin_2 PF14523.6 OQS06048.1 - 0.64 10.4 4.3 3.3 8.1 1.1 2.5 2 0 0 2 2 2 0 Syntaxin-like protein FlaG PF03646.15 OQS06048.1 - 2.1 8.6 5.6 24 5.1 1.3 2.6 2 0 0 2 2 2 0 FlaG protein SAM_1 PF00536.30 OQS06049.1 - 5.2e-08 33.2 0.0 1.3e-07 31.9 0.0 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 OQS06049.1 - 7.1e-08 32.4 0.0 3.6e-07 30.2 0.0 2.2 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) fn3 PF00041.21 OQS06049.1 - 8.8e-08 32.4 1.1 1.4e-05 25.3 0.0 3.1 3 0 0 3 3 3 1 Fibronectin type III domain EF-hand_1 PF00036.32 OQS06049.1 - 1e-05 24.7 3.0 0.088 12.4 0.0 4.0 4 0 0 4 4 4 2 EF hand EF-hand_6 PF13405.6 OQS06049.1 - 2.6e-05 23.8 0.4 0.31 11.1 0.0 3.9 3 0 0 3 3 3 2 EF-hand domain EF-hand_7 PF13499.6 OQS06049.1 - 0.00028 21.3 5.6 0.01 16.3 1.3 4.2 2 1 0 2 2 2 1 EF-hand domain pair fn3_4 PF16794.5 OQS06049.1 - 0.0011 18.8 0.0 0.0045 16.9 0.0 2.1 1 0 0 1 1 1 1 Fibronectin-III type domain EF-hand_5 PF13202.6 OQS06049.1 - 0.0057 16.1 7.3 0.048 13.2 0.0 3.7 4 0 0 4 4 4 2 EF hand zf-AN1 PF01428.16 OQS06049.1 - 0.58 10.4 9.5 1.2 9.3 9.5 1.4 1 0 0 1 1 1 0 AN1-like Zinc finger FYVE PF01363.21 OQS06050.1 - 0.00063 19.8 20.7 0.0018 18.4 20.7 1.8 1 0 0 1 1 1 1 FYVE zinc finger Ion_trans PF00520.31 OQS06051.1 - 0.0026 17.0 8.1 0.0047 16.2 8.1 1.3 1 0 0 1 1 1 1 Ion transport protein Glyco_hydro_53 PF07745.13 OQS06051.1 - 0.0053 15.8 0.2 0.025 13.6 0.0 2.0 2 0 0 2 2 2 1 Glycosyl hydrolase family 53 SOG2 PF10428.9 OQS06051.1 - 4.1 6.5 15.5 6.1 5.9 15.5 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein DcpS_C PF11969.8 OQS06052.1 - 8.3e-24 84.3 3.8 1.3e-23 83.6 3.8 1.3 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding HIT PF01230.23 OQS06052.1 - 1.8e-13 51.0 2.7 3.8e-13 50.0 2.7 1.6 1 0 0 1 1 1 1 HIT domain zf-C2HE PF16278.5 OQS06052.1 - 6e-13 49.0 1.3 1.3e-12 47.9 1.3 1.6 1 0 0 1 1 1 1 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_3rep PF18868.1 OQS06052.1 - 5.4e-06 27.1 0.4 9.5e-06 26.3 0.4 1.4 1 0 0 1 1 1 1 Zinc finger C2H2-type, 3 repeats Actin_micro PF17003.5 OQS06052.1 - 0.012 14.8 0.5 0.018 14.3 0.2 1.4 1 1 0 1 1 1 0 Putative actin-like family zf-C2H2 PF00096.26 OQS06052.1 - 0.035 14.6 0.3 0.095 13.2 0.3 1.8 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-C2H2_2 PF12756.7 OQS06052.1 - 0.14 12.5 2.6 0.15 12.4 0.6 2.1 1 1 2 3 3 3 0 C2H2 type zinc-finger (2 copies) SVIP PF15811.5 OQS06053.1 - 0.0014 19.1 2.0 0.0014 19.1 2.0 1.5 2 0 0 2 2 2 1 Small VCP/p97-interacting protein Yip1 PF04893.17 OQS06054.1 - 8.4e-05 22.4 17.5 0.00015 21.5 17.4 1.5 1 1 0 1 1 1 1 Yip1 domain Pkinase PF00069.25 OQS06055.1 - 8.8e-66 222.0 0.0 1.2e-65 221.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQS06055.1 - 2.8e-29 102.2 0.0 6.2e-29 101.1 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OQS06055.1 - 1.6e-05 24.4 0.0 2.7e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 OQS06055.1 - 0.00025 20.4 0.0 0.00049 19.5 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 OQS06055.1 - 0.011 14.7 0.1 0.021 13.8 0.1 1.5 1 1 0 1 1 1 0 Haspin like kinase domain RIO1 PF01163.22 OQS06055.1 - 0.017 14.8 0.4 0.054 13.1 0.4 1.8 1 0 0 1 1 1 0 RIO1 family FTA2 PF13095.6 OQS06055.1 - 0.032 13.9 0.1 0.099 12.3 0.0 1.8 1 1 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Pkinase_fungal PF17667.1 OQS06055.1 - 1.1 8.0 5.9 0.32 9.7 0.1 2.4 2 1 1 3 3 3 0 Fungal protein kinase DUF489 PF04356.12 OQS06056.1 - 0.021 14.8 0.1 0.033 14.2 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF489) CHIP_TPR_N PF18391.1 OQS06056.1 - 0.058 14.2 6.1 1.2 9.9 1.3 2.5 2 0 0 2 2 2 0 CHIP N-terminal tetratricopeptide repeat domain Bacillus_HBL PF05791.11 OQS06056.1 - 0.24 11.2 3.0 1.7 8.4 0.1 2.8 1 1 2 3 3 3 0 Bacillus haemolytic enterotoxin (HBL) Frankia_peptide PF14407.6 OQS06056.1 - 0.58 10.2 2.7 2.8 8.0 0.0 3.0 3 1 0 3 3 3 0 Ribosomally synthesized peptide prototyped by Frankia Franean1_4349. PI3_PI4_kinase PF00454.27 OQS06057.1 - 5.6e-26 91.9 0.3 9e-21 74.8 0.0 2.6 2 1 1 3 3 3 2 Phosphatidylinositol 3- and 4-kinase Pkinase PF00069.25 OQS06058.1 - 2.1e-16 60.1 0.1 1.2e-08 34.7 0.0 2.8 1 1 2 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 OQS06058.1 - 1.2e-11 44.4 0.0 0.00012 21.4 0.0 2.3 1 1 1 2 2 2 2 Protein tyrosine kinase UCH PF00443.29 OQS06059.1 - 1.7e-61 208.0 0.0 2.4e-61 207.5 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 OQS06059.1 - 3.8e-15 56.3 1.7 1.6e-07 31.2 0.0 3.4 3 0 0 3 3 3 3 Ubiquitin carboxyl-terminal hydrolase USP7_C2 PF14533.6 OQS06059.1 - 0.0023 17.7 0.0 0.0043 16.8 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-specific protease C-terminal EF-hand_7 PF13499.6 OQS06059.1 - 0.019 15.4 0.0 9.9 6.7 0.0 2.4 1 1 0 2 2 2 0 EF-hand domain pair EF-hand_8 PF13833.6 OQS06059.1 - 0.058 13.3 0.0 0.86 9.5 0.0 2.5 1 1 1 2 2 2 0 EF-hand domain pair Peptidase_C98 PF15499.6 OQS06059.1 - 0.28 10.6 3.8 7 6.0 0.0 3.4 4 0 0 4 4 4 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase Pkinase PF00069.25 OQS06060.1 - 3.8e-20 72.3 0.9 1.2e-16 60.9 0.0 2.8 1 1 2 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 OQS06060.1 - 4.3e-15 55.7 2.3 1.5e-10 40.8 0.0 3.2 1 1 2 3 3 3 3 Protein tyrosine kinase PAZ_siRNAbind PF12212.8 OQS06060.1 - 0.053 13.3 0.0 0.074 12.9 0.0 1.3 1 0 0 1 1 1 0 PAZ domain FYVE PF01363.21 OQS06061.1 - 4.3e-20 71.6 4.2 4.3e-20 71.6 4.2 2.7 3 1 0 3 3 3 1 FYVE zinc finger DEP PF00610.21 OQS06061.1 - 0.00017 21.6 0.0 0.00033 20.6 0.0 1.5 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) PLATZ PF04640.14 OQS06061.1 - 0.0054 17.3 2.1 0.0054 17.3 2.1 2.6 3 1 0 3 3 3 1 PLATZ transcription factor FYVE_2 PF02318.16 OQS06061.1 - 0.0076 16.5 2.5 0.0076 16.5 2.5 2.3 2 0 0 2 2 2 1 FYVE-type zinc finger PknG_TPR PF16918.5 OQS06061.1 - 0.13 10.9 0.0 0.18 10.5 0.0 1.1 1 0 0 1 1 1 0 Protein kinase G tetratricopeptide repeat C1_1 PF00130.22 OQS06061.1 - 0.22 11.4 12.1 0.24 11.3 5.2 2.5 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Zn-ribbon_8 PF09723.10 OQS06061.1 - 4.1 7.6 18.1 1.4 9.1 1.6 4.1 3 2 1 4 4 4 0 Zinc ribbon domain Hydrolase_4 PF12146.8 OQS06062.1 - 3.3e-12 46.2 0.1 9.6e-10 38.1 0.0 2.2 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 OQS06062.1 - 5.2e-08 32.9 0.6 2.2e-06 27.5 0.2 2.6 2 1 1 3 3 3 1 alpha/beta hydrolase fold Peptidase_S15 PF02129.18 OQS06062.1 - 6.9e-07 29.1 0.0 2e-06 27.6 0.0 1.8 2 0 0 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) zf-RanBP PF00641.18 OQS06062.1 - 1.9e-05 23.9 2.4 4.8e-05 22.6 2.4 1.6 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others Abhydrolase_6 PF12697.7 OQS06062.1 - 4.6e-05 24.1 0.0 9.9e-05 23.0 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family PhoPQ_related PF10142.9 OQS06062.1 - 0.0021 16.8 0.0 0.0032 16.2 0.0 1.2 1 0 0 1 1 1 1 PhoPQ-activated pathogenicity-related protein DUF35_N PF12172.8 OQS06062.1 - 0.0095 15.8 0.9 0.021 14.7 0.9 1.6 1 0 0 1 1 1 1 Rubredoxin-like zinc ribbon domain (DUF35_N) Esterase PF00756.20 OQS06062.1 - 0.02 14.6 0.0 0.13 11.9 0.0 2.1 1 1 0 1 1 1 0 Putative esterase FSH1 PF03959.13 OQS06062.1 - 0.073 12.7 0.0 0.13 11.9 0.0 1.4 1 0 0 1 1 1 0 Serine hydrolase (FSH1) FHA PF00498.26 OQS06063.1 - 2e-15 56.9 0.0 3.6e-15 56.0 0.0 1.5 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 OQS06063.1 - 9.1e-07 29.1 0.0 0.025 14.9 0.0 2.3 2 0 0 2 2 2 2 Inner membrane component of T3SS, cytoplasmic domain Circo_capsid PF02443.15 OQS06063.1 - 4 7.0 8.2 5.8 6.4 8.2 1.3 1 0 0 1 1 1 0 Circovirus capsid protein BolA PF01722.18 OQS06064.1 - 1.5e-05 25.2 0.0 3.6e-05 24.0 0.0 1.7 1 1 0 1 1 1 1 BolA-like protein Apc13p PF05839.11 OQS06064.1 - 0.0055 16.9 0.4 0.016 15.4 0.4 1.7 1 1 0 1 1 1 1 Apc13p protein DNA_pol_A_exo1 PF01612.20 OQS06065.1 - 1.7e-21 76.7 0.0 2.9e-21 76.0 0.0 1.3 1 0 0 1 1 1 1 3'-5' exonuclease Sigma_reg_N PF13800.6 OQS06066.1 - 0.15 12.3 1.0 0.28 11.5 0.4 1.8 2 0 0 2 2 2 0 Sigma factor regulator N-terminal Hydrolase_4 PF12146.8 OQS06067.1 - 1.9e-10 40.4 0.1 1.3e-09 37.7 0.1 2.1 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 OQS06067.1 - 2e-05 25.3 0.0 2.7e-05 24.9 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 OQS06067.1 - 0.00059 19.6 0.2 0.37 10.4 0.1 3.0 2 1 1 3 3 3 2 alpha/beta hydrolase fold PhoPQ_related PF10142.9 OQS06067.1 - 0.0067 15.1 0.1 0.0093 14.7 0.1 1.2 1 0 0 1 1 1 1 PhoPQ-activated pathogenicity-related protein DUF900 PF05990.12 OQS06067.1 - 0.11 12.0 0.0 0.17 11.4 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Peptidase_S15 PF02129.18 OQS06067.1 - 0.11 12.0 0.0 0.28 10.7 0.0 1.7 3 0 0 3 3 3 0 X-Pro dipeptidyl-peptidase (S15 family) PTS_2-RNA PF01885.16 OQS06068.1 - 1.7e-61 207.4 0.0 2e-61 207.2 0.0 1.0 1 0 0 1 1 1 1 RNA 2'-phosphotransferase, Tpt1 / KptA family adh_short_C2 PF13561.6 OQS06069.1 - 0.00026 20.6 0.0 0.00071 19.2 0.0 1.7 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Cauli_AT PF03233.13 OQS06069.1 - 6.3 6.7 7.6 0.89 9.5 1.1 2.4 1 1 1 2 2 2 0 Aphid transmission protein ATP-synt_J PF04911.12 OQS06071.1 - 0.035 13.7 0.0 0.091 12.4 0.0 1.7 1 0 0 1 1 1 0 ATP synthase j chain dNK PF01712.19 OQS06071.1 - 0.085 12.7 0.5 1 9.2 0.0 2.3 2 0 0 2 2 2 0 Deoxynucleoside kinase RabGAP-TBC PF00566.18 OQS06072.1 - 5.1e-55 186.5 0.2 7.1e-55 186.0 0.2 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Ank_4 PF13637.6 OQS06073.1 - 5.5e-09 36.4 0.4 6.9e-06 26.5 0.1 2.7 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 OQS06073.1 - 6.6e-07 29.8 0.0 1.6e-06 28.6 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OQS06073.1 - 9.6e-07 29.0 0.1 2.6e-06 27.6 0.1 1.8 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.30 OQS06073.1 - 4.6e-06 26.8 0.2 0.0018 18.7 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.6 OQS06073.1 - 0.00013 22.1 0.1 0.0095 16.4 0.0 2.7 2 0 0 2 2 2 1 Ankyrin repeat Occludin_ELL PF07303.13 OQS06073.1 - 8.2 7.2 11.0 1.7 9.4 1.5 3.1 2 2 0 2 2 2 0 Occludin homology domain Ribosomal_L7Ae PF01248.26 OQS06074.1 - 6e-26 90.0 0.0 8.2e-26 89.6 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family PELOTA_1 PF15608.6 OQS06074.1 - 4.6e-05 23.2 0.0 6e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 PELOTA RNA binding domain RNase_P_pop3 PF08228.11 OQS06074.1 - 0.0052 16.8 0.0 0.0053 16.8 0.0 1.1 1 0 0 1 1 1 1 RNase P subunit Pop3 Pkinase_Tyr PF07714.17 OQS06075.1 - 5.2e-58 196.4 0.0 6.6e-58 196.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OQS06075.1 - 5.9e-54 183.2 0.0 7.7e-54 182.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 OQS06075.1 - 0.00011 21.7 0.0 0.00014 21.3 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.11 OQS06075.1 - 0.00036 19.7 0.0 0.00051 19.2 0.0 1.2 1 0 0 1 1 1 1 Seadornavirus VP7 APH PF01636.23 OQS06075.1 - 0.00044 20.2 0.0 0.00067 19.6 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 OQS06075.1 - 0.012 14.5 0.0 0.018 14.0 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Pkinase PF00069.25 OQS06076.1 - 4.9e-132 439.1 0.0 7.4e-65 218.9 0.0 2.4 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OQS06076.1 - 1.1e-53 182.2 0.0 3.2e-27 95.5 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase WW PF00397.26 OQS06076.1 - 3.5e-19 68.6 6.5 3.2e-12 46.3 2.9 2.8 2 0 0 2 2 2 2 WW domain EF-hand_7 PF13499.6 OQS06076.1 - 2.9e-14 53.3 1.6 2.9e-14 53.3 1.6 3.3 4 0 0 4 4 3 1 EF-hand domain pair EF-hand_8 PF13833.6 OQS06076.1 - 1.4e-11 44.0 4.5 2.6e-11 43.2 0.1 3.0 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_6 PF13405.6 OQS06076.1 - 6.8e-11 41.2 1.6 0.00039 20.1 0.8 3.3 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.32 OQS06076.1 - 1e-10 40.4 7.9 3.2e-05 23.2 0.0 3.5 3 0 0 3 3 3 2 EF hand Haspin_kinase PF12330.8 OQS06076.1 - 4.4e-08 32.5 0.2 0.0015 17.6 0.0 2.6 2 0 0 2 2 2 2 Haspin like kinase domain Kdo PF06293.14 OQS06076.1 - 2.8e-06 26.9 1.4 0.057 12.8 0.1 2.4 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 OQS06076.1 - 3.1e-06 26.7 0.0 0.02 14.2 0.0 3.3 3 1 1 4 4 4 2 Kinase-like APH PF01636.23 OQS06076.1 - 1e-05 25.6 1.2 0.12 12.2 0.1 2.9 2 1 1 3 3 3 2 Phosphotransferase enzyme family EF-hand_5 PF13202.6 OQS06076.1 - 3.2e-05 23.2 8.1 0.0048 16.3 0.1 3.2 3 0 0 3 3 3 2 EF hand Pkinase_fungal PF17667.1 OQS06076.1 - 0.0062 15.4 0.4 0.94 8.2 0.1 2.5 2 0 0 2 2 2 1 Fungal protein kinase FTA2 PF13095.6 OQS06076.1 - 0.02 14.6 0.1 4.5 6.8 0.0 3.0 2 1 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Choline_kinase PF01633.20 OQS06076.1 - 0.09 12.3 0.1 18 4.8 0.0 2.7 3 0 0 3 3 3 0 Choline/ethanolamine kinase Pox_ser-thr_kin PF05445.11 OQS06076.1 - 0.2 10.6 0.2 12 4.8 0.0 2.3 2 0 0 2 2 2 0 Poxvirus serine/threonine protein kinase Arm-DNA-bind_1 PF09003.10 OQS06076.1 - 0.36 11.0 1.6 21 5.3 0.2 2.5 2 0 0 2 2 2 0 Bacteriophage lambda integrase, Arm DNA-binding domain DUF4682 PF15733.5 OQS06077.1 - 0.0084 16.7 0.1 0.018 15.7 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4682) IGPD PF00475.18 OQS06078.1 - 4.2e-62 208.7 0.5 7.2e-62 208.0 0.5 1.4 1 0 0 1 1 1 1 Imidazoleglycerol-phosphate dehydratase HAD_2 PF13419.6 OQS06078.1 - 1.4e-18 67.6 0.0 2.3e-18 66.9 0.0 1.4 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 OQS06078.1 - 1.5e-09 38.4 0.1 7e-09 36.3 0.1 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 OQS06078.1 - 3.1e-05 23.9 0.3 0.0001 22.3 0.0 2.0 2 0 0 2 2 2 1 HAD-hyrolase-like Pro_isomerase PF00160.21 OQS06079.1 - 5.6e-22 78.7 0.0 6.7e-22 78.4 0.0 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD HECT PF00632.25 OQS06080.1 - 2.6e-76 257.0 0.0 5.3e-76 256.0 0.0 1.4 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) zf-RanBP PF00641.18 OQS06080.1 - 0.00019 20.7 14.3 0.0013 18.0 2.5 3.2 3 0 0 3 3 3 2 Zn-finger in Ran binding protein and others Vps36-NZF-N PF16988.5 OQS06080.1 - 0.25 10.7 10.1 1.4 8.4 0.9 2.8 2 1 0 2 2 2 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain zf-Sec23_Sec24 PF04810.15 OQS06080.1 - 5.7 7.1 8.0 3.7 7.7 0.1 3.3 2 1 1 3 3 3 0 Sec23/Sec24 zinc finger TMEM117 PF15113.6 OQS06081.1 - 6.9e-31 107.6 15.9 4.9e-25 88.3 7.7 2.4 2 0 0 2 2 2 2 TMEM117 protein family Ion_trans_2 PF07885.16 OQS06081.1 - 9.5e-08 31.9 7.2 9.5e-08 31.9 7.2 4.0 3 0 0 3 3 3 1 Ion channel SK_channel PF03530.14 OQS06081.1 - 0.00077 19.4 1.0 0.00077 19.4 1.0 2.3 2 0 0 2 2 2 1 Calcium-activated SK potassium channel ZapB PF06005.12 OQS06081.1 - 0.043 14.2 1.6 17 5.9 0.1 3.3 3 0 0 3 3 3 0 Cell division protein ZapB TPR_19 PF14559.6 OQS06082.1 - 0.051 14.1 0.1 0.078 13.5 0.1 1.3 1 0 0 1 1 1 0 Tetratricopeptide repeat Thioredoxin PF00085.20 OQS06083.1 - 2.8e-62 207.1 0.1 4.3e-31 107.0 0.0 2.8 3 0 0 3 3 3 2 Thioredoxin ERp29 PF07749.12 OQS06083.1 - 1e-16 61.6 0.3 1.8e-16 60.8 0.3 1.4 1 0 0 1 1 1 1 Endoplasmic reticulum protein ERp29, C-terminal domain OST3_OST6 PF04756.13 OQS06083.1 - 3.7e-14 52.8 0.0 1.8e-07 30.8 0.0 2.8 2 1 1 3 3 3 2 OST3 / OST6 family, transporter family DUF4497 PF14924.6 OQS06083.1 - 1e-12 48.4 0.0 4.9e-12 46.3 0.0 2.2 1 1 0 1 1 1 1 Protein of unknown function (DUF4497) Thioredoxin_2 PF13098.6 OQS06083.1 - 1.4e-11 44.8 0.0 0.00021 21.7 0.0 2.8 2 0 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_7 PF13899.6 OQS06083.1 - 1.3e-07 31.7 0.0 0.0032 17.6 0.0 2.4 2 0 0 2 2 2 2 Thioredoxin-like Thioredoxin_8 PF13905.6 OQS06083.1 - 1.3e-06 28.6 0.1 0.033 14.5 0.0 3.4 2 2 2 4 4 4 2 Thioredoxin-like TraF PF13728.6 OQS06083.1 - 3.3e-05 23.8 0.0 0.0091 15.8 0.0 2.3 2 0 0 2 2 2 2 F plasmid transfer operon protein Thioredoxin_6 PF13848.6 OQS06083.1 - 9e-05 22.5 0.2 0.00056 19.9 0.1 2.5 2 1 0 2 2 2 1 Thioredoxin-like domain Redoxin PF08534.10 OQS06083.1 - 0.00033 20.4 0.1 0.8 9.4 0.0 2.4 2 0 0 2 2 2 2 Redoxin AhpC-TSA PF00578.21 OQS06083.1 - 0.0016 18.3 0.1 0.39 10.6 0.0 2.5 2 0 0 2 2 2 1 AhpC/TSA family Thioredoxin_9 PF14595.6 OQS06083.1 - 0.037 13.8 0.1 4.4 7.1 0.0 2.4 2 0 0 2 2 2 0 Thioredoxin Tcp10_C PF07202.13 OQS06084.1 - 2.3e-31 109.1 4.0 2.3e-31 109.1 4.0 2.7 3 1 1 4 4 4 1 T-complex protein 10 C-terminus Ribosomal_S4e PF00900.20 OQS06084.1 - 8e-30 102.6 2.6 1.5e-29 101.7 1.0 2.4 2 0 0 2 2 2 1 Ribosomal family S4e 40S_S4_C PF16121.5 OQS06084.1 - 7.6e-24 83.1 0.1 1.5e-23 82.1 0.1 1.5 1 0 0 1 1 1 1 40S ribosomal protein S4 C-terminus RS4NT PF08071.12 OQS06084.1 - 2.4e-18 66.0 9.0 6.4e-18 64.6 9.0 1.8 1 0 0 1 1 1 1 RS4NT (NUC023) domain S4 PF01479.25 OQS06084.1 - 9.4e-07 28.5 0.0 2e-06 27.4 0.0 1.6 1 0 0 1 1 1 1 S4 domain KOW PF00467.29 OQS06084.1 - 0.00069 19.5 0.2 0.00069 19.5 0.2 2.7 3 0 0 3 3 3 1 KOW motif KIAA1430 PF13879.6 OQS06085.1 - 2.4e-15 57.2 6.8 2.4e-15 57.2 6.8 3.9 4 0 0 4 4 4 1 KIAA1430 homologue IQ PF00612.27 OQS06085.1 - 7.5e-15 53.3 11.5 0.00012 21.5 0.3 4.7 4 0 0 4 4 4 3 IQ calmodulin-binding motif DUF4611 PF15387.6 OQS06085.1 - 0.51 10.6 6.9 1.9 8.7 6.9 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) Phage_holin_3_5 PF16085.5 OQS06086.1 - 0.72 10.0 6.1 1.9 8.7 6.1 1.6 1 0 0 1 1 1 0 Bacteriophage holin Hol, superfamily III KELK PF15796.5 OQS06086.1 - 2.9 8.4 16.0 5.3 7.6 4.4 3.1 1 1 2 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase SAM_1 PF00536.30 OQS06087.1 - 1.2e-11 44.9 0.1 2.9e-11 43.6 0.1 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 OQS06087.1 - 4.9e-09 36.2 0.1 9.2e-09 35.3 0.1 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) zf-FCS PF06467.14 OQS06087.1 - 0.018 15.0 5.6 0.038 13.9 5.6 1.6 1 0 0 1 1 1 0 MYM-type Zinc finger with FCS sequence motif HAUS-augmin3 PF14932.6 OQS06088.1 - 0.0039 16.8 0.5 0.0046 16.6 0.5 1.1 1 0 0 1 1 1 1 HAUS augmin-like complex subunit 3 PriC PF07445.12 OQS06088.1 - 0.0043 17.0 0.5 0.0054 16.7 0.5 1.1 1 0 0 1 1 1 1 Primosomal replication protein priC DUF1664 PF07889.12 OQS06088.1 - 0.027 14.5 0.2 0.037 14.1 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) GrpE PF01025.19 OQS06088.1 - 0.07 12.8 1.8 0.13 11.9 1.5 1.6 1 1 0 1 1 1 0 GrpE Pex2_Pex12 PF04757.14 OQS06089.1 - 1.7e-37 129.2 1.0 2.1e-37 128.9 1.0 1.1 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_2 PF13923.6 OQS06089.1 - 0.0023 17.7 4.5 0.0051 16.6 4.5 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 OQS06089.1 - 0.017 14.9 7.1 0.036 13.9 7.1 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 OQS06089.1 - 0.061 13.7 5.3 0.15 12.4 5.3 1.7 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4_4 PF15227.6 OQS06089.1 - 0.21 11.8 8.9 0.42 10.8 8.9 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.25 OQS06089.1 - 1 9.3 6.1 2.3 8.2 6.1 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Pkinase PF00069.25 OQS06090.1 - 3.5e-43 147.9 0.0 1.3e-31 109.9 0.0 2.5 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OQS06090.1 - 1.8e-25 89.7 0.0 1.4e-20 73.6 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 OQS06090.1 - 0.00053 19.4 0.0 0.00093 18.6 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 OQS06090.1 - 0.0053 16.1 0.0 0.021 14.2 0.0 1.9 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 OQS06090.1 - 0.11 12.1 0.1 11 5.5 0.0 2.4 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Rho_GDI PF02115.17 OQS06090.1 - 0.17 11.6 0.0 0.31 10.8 0.0 1.3 1 0 0 1 1 1 0 RHO protein GDP dissociation inhibitor FTHFS PF01268.19 OQS06091.1 - 1.2e-247 822.6 0.5 1.3e-247 822.4 0.5 1.0 1 0 0 1 1 1 1 Formate--tetrahydrofolate ligase AAA_26 PF13500.6 OQS06091.1 - 0.0041 17.0 0.3 5 6.9 0.0 2.9 3 0 0 3 3 3 2 AAA domain B12-binding PF02310.19 OQS06091.1 - 0.011 15.7 0.6 13 5.8 0.0 3.5 3 0 0 3 3 3 0 B12 binding domain EspB_PE PF18625.1 OQS06091.1 - 0.12 12.9 0.9 0.29 11.6 0.1 2.2 2 0 0 2 2 2 0 ESX-1 secreted protein B PE domain AP_endonuc_2 PF01261.24 OQS06091.1 - 0.14 11.6 0.0 0.25 10.8 0.0 1.3 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel Dynactin_p22 PF07426.11 OQS06092.1 - 1.5e-15 57.5 4.7 1.8e-15 57.2 4.7 1.1 1 0 0 1 1 1 1 Dynactin subunit p22 Matrilin_ccoil PF10393.9 OQS06092.1 - 0.032 14.1 2.6 3.8 7.5 0.0 3.0 3 0 0 3 3 3 0 Trimeric coiled-coil oligomerisation domain of matrilin MtrB PF05440.12 OQS06092.1 - 0.038 14.4 0.3 2.7 8.5 0.0 2.9 3 0 0 3 3 3 0 Tetrahydromethanopterin S-methyltransferase subunit B ABC_tran_CTD PF16326.5 OQS06092.1 - 0.17 12.2 0.1 0.17 12.2 0.1 2.9 2 1 1 3 3 3 0 ABC transporter C-terminal domain Proteasome PF00227.26 OQS06093.1 - 2.2e-43 147.9 0.1 2.9e-43 147.6 0.1 1.2 1 0 0 1 1 1 1 Proteasome subunit DLH PF01738.18 OQS06094.1 - 4.6e-08 32.9 0.0 1.2e-07 31.5 0.0 1.7 1 1 0 1 1 1 1 Dienelactone hydrolase family RRM_1 PF00076.22 OQS06096.1 - 5.2e-26 90.3 0.2 1.1e-12 47.6 0.0 3.5 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PHD20L1_u1 PF16660.5 OQS06096.1 - 0.006 17.3 1.5 0.01 16.6 0.7 1.8 1 1 0 1 1 1 1 PHD finger protein 20-like protein 1 Pup PF05639.11 OQS06096.1 - 0.33 11.9 5.0 0.086 13.8 1.3 1.9 2 0 0 2 2 2 0 Pup-like protein PUB PF09409.10 OQS06097.1 - 1.7e-16 59.9 0.1 4.9e-16 58.4 0.1 1.8 1 0 0 1 1 1 1 PUB domain HTH_12 PF08461.10 OQS06098.1 - 6e-07 29.3 2.3 0.057 13.4 0.0 5.4 5 0 0 5 5 5 2 Ribonuclease R winged-helix domain DUF384 PF04064.13 OQS06098.1 - 0.0002 21.1 1.5 4 7.4 0.0 4.4 4 0 0 4 4 4 1 Domain of unknown function (DUF384) DUF5309 PF17236.2 OQS06098.1 - 0.079 12.3 0.4 2.6 7.3 0.0 3.1 3 0 0 3 3 3 0 Family of unknown function (DUF5309) FeoB_Cyto PF17910.1 OQS06098.1 - 0.48 11.0 7.0 34 5.1 1.5 4.2 3 2 0 3 3 3 0 FeoB cytosolic helical domain Ribosomal_L11 PF00298.19 OQS06098.1 - 0.83 10.2 7.7 11 6.6 0.1 4.6 5 0 0 5 5 5 0 Ribosomal protein L11, RNA binding domain DLH PF01738.18 OQS06099.1 - 1.3e-09 38.0 0.0 1.6e-09 37.7 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Pkinase_Tyr PF07714.17 OQS06100.1 - 7.3e-109 363.0 0.0 3.4e-54 183.8 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 OQS06100.1 - 3e-107 357.9 0.0 3.3e-54 184.0 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_fungal PF17667.1 OQS06100.1 - 2.2e-09 36.6 0.2 0.00085 18.2 0.0 2.1 2 0 0 2 2 2 2 Fungal protein kinase Kdo PF06293.14 OQS06100.1 - 9.9e-07 28.3 0.0 0.029 13.7 0.0 2.4 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 OQS06100.1 - 3.4e-06 26.6 0.0 0.027 13.8 0.0 2.5 2 0 0 2 2 2 2 Kinase-like Crystall PF00030.19 OQS06100.1 - 1.4e-05 25.2 4.8 0.02 15.1 0.3 3.1 3 0 0 3 3 3 2 Beta/Gamma crystallin APH PF01636.23 OQS06100.1 - 0.00016 21.7 0.0 0.44 10.4 0.0 2.3 2 0 0 2 2 2 2 Phosphotransferase enzyme family Haspin_kinase PF12330.8 OQS06100.1 - 0.0013 17.8 3.5 0.83 8.5 0.5 3.3 2 2 0 2 2 2 2 Haspin like kinase domain FTA2 PF13095.6 OQS06100.1 - 0.0013 18.4 1.5 8.9 5.9 0.0 3.8 4 0 0 4 4 4 1 Kinetochore Sim4 complex subunit FTA2 Syndecan PF01034.20 OQS06100.1 - 0.0021 17.9 1.5 1.4 8.9 0.0 3.3 3 0 0 3 3 3 2 Syndecan domain ABC1 PF03109.16 OQS06100.1 - 0.0068 16.6 0.0 1.5 9.0 0.0 2.5 2 0 0 2 2 2 1 ABC1 family Protocadherin PF08374.11 OQS06100.1 - 0.023 14.7 4.9 0.39 10.7 1.4 2.3 2 0 0 2 2 2 0 Protocadherin Amnionless PF14828.6 OQS06100.1 - 0.028 13.3 0.1 0.19 10.5 0.0 1.9 2 0 0 2 2 2 0 Amnionless EphA2_TM PF14575.6 OQS06100.1 - 0.053 14.4 2.9 10 7.1 0.7 2.4 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain SKG6 PF08693.10 OQS06100.1 - 0.84 9.1 5.7 20 4.7 3.6 2.5 2 0 0 2 2 2 0 Transmembrane alpha-helix domain Cyclin_N PF00134.23 OQS06102.1 - 1.2e-39 134.9 1.7 3.7e-38 130.1 0.9 2.6 2 1 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 OQS06102.1 - 1.5e-27 96.0 0.8 1.5e-27 96.0 0.8 2.1 2 0 0 2 2 2 1 Cyclin, C-terminal domain PLAC8 PF04749.17 OQS06102.1 - 2.9e-17 63.5 12.0 2.9e-17 63.5 12.0 2.1 2 0 0 2 2 2 1 PLAC8 family zf-CCHC_4 PF14392.6 OQS06102.1 - 5.6 6.8 9.0 3.9 7.3 0.8 3.2 3 0 0 3 3 3 0 Zinc knuckle LRR_8 PF13855.6 OQS06103.1 - 5.4e-14 51.7 13.8 0.0035 17.1 0.2 5.9 5 2 3 8 8 8 5 Leucine rich repeat LRR_4 PF12799.7 OQS06103.1 - 0.00083 19.7 26.8 0.047 14.1 0.6 6.6 4 2 3 7 7 7 3 Leucine Rich repeats (2 copies) LPD28 PF18843.1 OQS06103.1 - 0.18 11.4 0.0 3.1 7.5 0.0 2.8 3 0 0 3 3 3 0 Large polyvalent protein associated domain 28 SLC3A2_N PF16028.5 OQS06103.1 - 4.9 6.8 11.4 5.6 6.6 2.2 3.2 3 0 0 3 3 3 0 Solute carrier family 3 member 2 N-terminus Notch PF00066.17 OQS06103.1 - 5.5 7.5 5.7 6.6 7.3 2.9 2.6 2 0 0 2 2 2 0 LNR domain 2OG-FeII_Oxy PF03171.20 OQS06104.1 - 4e-24 85.0 0.0 7.3e-24 84.2 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.6 OQS06104.1 - 1.8e-23 83.5 0.0 2.9e-23 82.9 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal TSC22 PF01166.18 OQS06105.1 - 0.015 15.6 2.7 0.015 15.6 2.7 2.8 2 0 0 2 2 2 0 TSC-22/dip/bun family CC2-LZ PF16516.5 OQS06105.1 - 0.035 14.5 15.4 0.26 11.7 2.7 3.1 2 0 0 2 2 2 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator RasGAP_C PF03836.15 OQS06105.1 - 3.2 7.9 17.6 0.31 11.2 5.0 2.7 1 1 1 2 2 2 0 RasGAP C-terminus VWA_2 PF13519.6 OQS06106.1 - 3.1e-21 76.0 0.3 1.1e-20 74.2 0.1 2.1 3 0 0 3 3 3 1 von Willebrand factor type A domain Ssl1 PF04056.14 OQS06106.1 - 6.3e-07 29.4 0.2 9.5e-07 28.8 0.2 1.2 1 0 0 1 1 1 1 Ssl1-like VWA PF00092.28 OQS06106.1 - 7.5e-06 26.3 0.5 1.3e-05 25.5 0.5 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain COP23 PF14218.6 OQS06106.1 - 0.092 12.5 0.0 0.83 9.4 0.0 2.1 2 0 0 2 2 2 0 Circadian oscillating protein COP23 UIM PF02809.20 OQS06106.1 - 0.092 12.7 1.8 0.11 12.5 0.1 2.1 2 0 0 2 2 2 0 Ubiquitin interaction motif F5_F8_type_C PF00754.25 OQS06107.1 - 7.7e-08 32.5 0.6 1.7e-07 31.4 0.6 1.6 1 0 0 1 1 1 1 F5/8 type C domain XRCC1_N PF01834.16 OQS06107.1 - 9.8e-06 25.6 0.1 2.6e-05 24.2 0.1 1.7 1 0 0 1 1 1 1 XRCC1 N terminal domain zf-C2HC_2 PF13913.6 OQS06107.1 - 0.0014 18.5 1.2 0.0028 17.5 1.2 1.5 1 0 0 1 1 1 1 zinc-finger of a C2HC-type GIT_CC PF16559.5 OQS06107.1 - 0.33 10.9 3.8 0.28 11.1 1.1 2.3 2 0 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor UPF0242 PF06785.11 OQS06107.1 - 5 7.2 18.2 0.078 13.1 2.6 2.5 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus AAA PF00004.29 OQS06108.1 - 1.4e-15 57.9 0.0 2.4e-15 57.1 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rep_fac_C PF08542.11 OQS06108.1 - 7.1e-14 52.0 0.0 3.1e-13 49.9 0.0 2.1 2 0 0 2 2 2 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.6 OQS06108.1 - 1e-13 51.4 0.0 5.7e-10 39.2 0.0 2.3 1 1 1 2 2 2 2 DNA polymerase III, delta subunit Rad17 PF03215.15 OQS06108.1 - 8.1e-07 29.1 0.0 5e-06 26.6 0.0 2.0 1 1 0 1 1 1 1 Rad17 P-loop domain DNA_pol3_delta PF06144.13 OQS06108.1 - 1.7e-05 24.6 0.0 2.8e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA_16 PF13191.6 OQS06108.1 - 4.1e-05 24.0 0.0 0.00011 22.6 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 OQS06108.1 - 5.6e-05 23.4 0.6 0.65 10.3 0.0 3.3 1 1 3 4 4 4 2 AAA domain RuvB_N PF05496.12 OQS06108.1 - 5.7e-05 22.9 0.0 0.0001 22.1 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain ResIII PF04851.15 OQS06108.1 - 0.00021 21.4 0.0 0.007 16.4 0.0 2.2 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit AAA_14 PF13173.6 OQS06108.1 - 0.00023 21.2 0.0 0.00044 20.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_7 PF12775.7 OQS06108.1 - 0.00044 19.8 0.0 0.00076 19.0 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_24 PF13479.6 OQS06108.1 - 0.00089 19.0 0.0 0.0016 18.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.14 OQS06108.1 - 0.0011 19.0 1.8 0.0037 17.2 0.1 2.7 3 1 0 3 3 2 1 AAA domain (dynein-related subfamily) AAA_30 PF13604.6 OQS06108.1 - 0.0015 18.2 0.0 0.0042 16.8 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_assoc_2 PF16193.5 OQS06108.1 - 0.0017 18.6 0.0 0.0049 17.2 0.0 1.8 2 0 0 2 2 1 1 AAA C-terminal domain ATPase_2 PF01637.18 OQS06108.1 - 0.002 18.1 0.0 0.0037 17.2 0.0 1.4 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_11 PF13086.6 OQS06108.1 - 0.0065 16.3 0.0 0.022 14.6 0.0 1.8 1 1 1 2 2 2 1 AAA domain DUF815 PF05673.13 OQS06108.1 - 0.014 14.6 0.0 0.021 14.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) DEAD PF00270.29 OQS06108.1 - 0.023 14.5 0.2 0.44 10.3 0.0 2.5 2 1 1 3 3 3 0 DEAD/DEAH box helicase MCM PF00493.23 OQS06108.1 - 0.041 13.0 0.0 0.07 12.2 0.0 1.3 1 0 0 1 1 1 0 MCM P-loop domain Mg_chelatase PF01078.21 OQS06108.1 - 0.048 13.0 0.1 0.16 11.4 0.1 1.7 1 1 1 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_18 PF13238.6 OQS06108.1 - 0.058 13.9 0.0 0.11 13.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain TniB PF05621.11 OQS06108.1 - 0.067 12.6 0.1 0.51 9.7 0.0 2.0 1 1 1 2 2 2 0 Bacterial TniB protein PhoH PF02562.16 OQS06108.1 - 0.078 12.4 0.0 1.2 8.6 0.0 2.1 2 0 0 2 2 2 0 PhoH-like protein AAA_19 PF13245.6 OQS06108.1 - 0.079 13.3 0.1 1.7 8.9 0.0 2.3 1 1 1 2 2 2 0 AAA domain KfrA_N PF11740.8 OQS06108.1 - 0.094 13.4 0.0 0.17 12.6 0.0 1.4 1 0 0 1 1 1 0 Plasmid replication region DNA-binding N-term IstB_IS21 PF01695.17 OQS06108.1 - 0.096 12.4 0.0 0.21 11.3 0.0 1.5 1 1 0 1 1 1 0 IstB-like ATP binding protein SNF2_N PF00176.23 OQS06108.1 - 0.11 11.1 0.0 0.5 9.0 0.0 2.0 2 0 0 2 2 2 0 SNF2 family N-terminal domain AAA_3 PF07726.11 OQS06108.1 - 0.14 12.0 0.0 0.31 10.9 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 OQS06108.1 - 0.16 12.4 0.0 0.44 11.0 0.0 1.8 1 0 0 1 1 1 0 RNA helicase TIP49 PF06068.13 OQS06108.1 - 0.16 11.1 0.0 0.25 10.5 0.0 1.2 1 0 0 1 1 1 0 TIP49 P-loop domain Mannosyl_trans3 PF11051.8 OQS06109.1 - 8.7e-18 64.6 0.0 1.2e-17 64.1 0.0 1.2 1 0 0 1 1 1 1 Mannosyltransferase putative Acid_PPase PF12689.7 OQS06110.1 - 9.1e-54 181.8 0.0 1e-53 181.6 0.0 1.0 1 0 0 1 1 1 1 Acid Phosphatase ABC_membrane PF00664.23 OQS06111.1 - 1.4e-05 24.9 13.9 1.4e-05 24.9 13.9 2.3 2 1 1 3 3 3 2 ABC transporter transmembrane region Aha1_N PF09229.11 OQS06113.1 - 6.7e-18 65.2 0.0 1.3e-17 64.3 0.0 1.5 1 0 0 1 1 1 1 Activator of Hsp90 ATPase, N-terminal TPR_1 PF00515.28 OQS06113.1 - 2.8e-08 33.2 2.1 0.00075 19.2 0.1 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 OQS06113.1 - 6e-08 32.2 0.9 0.0024 17.8 0.1 4.3 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 OQS06113.1 - 0.00032 20.7 3.0 0.059 13.6 0.1 4.5 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_16 PF13432.6 OQS06113.1 - 0.015 15.9 0.5 0.23 12.2 0.2 2.8 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_11 PF13414.6 OQS06113.1 - 0.043 13.5 2.9 0.46 10.2 0.0 3.2 5 0 0 5 5 5 0 TPR repeat TPR_14 PF13428.6 OQS06113.1 - 0.057 14.3 0.4 38 5.5 0.1 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat MIT PF04212.18 OQS06113.1 - 0.07 13.2 0.4 0.72 10.0 0.1 2.5 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain TPR_6 PF13174.6 OQS06113.1 - 1.7 9.5 3.8 20 6.1 0.2 3.4 2 1 1 3 3 3 0 Tetratricopeptide repeat Sensor PF13796.6 OQS06114.1 - 4e-05 23.7 16.2 0.0072 16.4 7.9 2.1 2 0 0 2 2 2 2 Putative sensor Glycos_transf_4 PF00953.21 OQS06115.1 - 9e-35 120.0 8.8 9e-35 120.0 8.8 1.6 2 0 0 2 2 2 1 Glycosyl transferase family 4 DUF805 PF05656.14 OQS06115.1 - 0.91 10.0 7.6 0.11 12.9 1.7 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF805) DHR-2 PF06920.13 OQS06116.1 - 1.6e-41 142.6 5.2 7.3e-38 130.5 0.0 3.7 2 1 1 3 3 3 2 Dock homology region 2 DOCK-C2 PF14429.6 OQS06116.1 - 2.4e-32 112.3 0.1 3.4e-31 108.6 0.1 2.5 1 1 0 1 1 1 1 C2 domain in Dock180 and Zizimin proteins RIX1 PF08167.12 OQS06116.1 - 0.079 12.7 3.3 0.54 10.0 0.6 3.0 2 0 0 2 2 2 0 rRNA processing/ribosome biogenesis GMC_oxred_N PF00732.19 OQS06117.1 - 2.6e-51 174.7 0.7 5.9e-51 173.6 0.3 1.7 2 0 0 2 2 2 1 GMC oxidoreductase AA_permease_2 PF13520.6 OQS06117.1 - 8.2e-42 143.5 45.2 8.2e-42 143.5 45.2 2.1 2 0 0 2 2 2 1 Amino acid permease GMC_oxred_C PF05199.13 OQS06117.1 - 1.5e-24 87.1 0.2 1.8e-23 83.7 0.0 2.3 2 0 0 2 2 2 1 GMC oxidoreductase FAD_binding_2 PF00890.24 OQS06117.1 - 5.2e-07 29.1 3.0 2.6e-06 26.8 0.7 2.2 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.24 OQS06117.1 - 1.1e-05 25.2 8.2 0.00034 20.3 8.2 2.2 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 OQS06117.1 - 3.6e-05 23.9 2.5 8.7e-05 22.7 1.5 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 OQS06117.1 - 3.9e-05 23.0 0.0 0.0008 18.7 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 OQS06117.1 - 0.0002 20.7 0.3 0.00038 19.8 0.3 1.4 1 0 0 1 1 1 1 FAD binding domain ApbA PF02558.16 OQS06117.1 - 0.0048 16.5 0.0 0.011 15.4 0.0 1.6 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA HI0933_like PF03486.14 OQS06117.1 - 0.0049 15.6 3.2 0.0075 15.0 0.6 2.1 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox PF00070.27 OQS06117.1 - 0.029 14.9 0.3 0.42 11.2 0.1 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 OQS06117.1 - 0.03 13.5 0.1 0.059 12.6 0.1 1.4 1 0 0 1 1 1 0 Thi4 family Pyr_redox_3 PF13738.6 OQS06117.1 - 0.053 12.8 0.1 0.14 11.4 0.0 1.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 OQS06117.1 - 0.1 11.6 0.0 0.2 10.7 0.0 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein FAD_oxidored PF12831.7 OQS06117.1 - 0.44 9.8 2.0 0.67 9.2 2.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase Rer1 PF03248.13 OQS06120.1 - 1.9e-66 223.0 7.5 2.3e-66 222.8 7.5 1.0 1 0 0 1 1 1 1 Rer1 family DUF2208 PF09973.9 OQS06120.1 - 0.018 14.7 0.1 0.018 14.7 0.1 1.7 2 0 0 2 2 2 0 Predicted membrane protein (DUF2208) Sensor PF13796.6 OQS06121.1 - 2.3e-09 37.5 3.6 3.7e-09 36.9 3.6 1.3 1 1 0 1 1 1 1 Putative sensor DUF2228 PF10228.9 OQS06122.1 - 7.9e-42 143.7 0.0 7.9e-42 143.7 0.0 2.9 3 1 0 3 3 3 1 Uncharacterised conserved protein (DUF2228) Ribosomal_L36e PF01158.18 OQS06123.1 - 1.7e-34 117.9 1.9 1.9e-34 117.7 1.9 1.0 1 0 0 1 1 1 1 Ribosomal protein L36e SMP_LBD PF17047.5 OQS06124.1 - 2.6e-14 53.1 0.0 4.2e-14 52.4 0.0 1.4 1 0 0 1 1 1 1 Synaptotagmin-like mitochondrial-lipid-binding domain C2 PF00168.30 OQS06124.1 - 8.7e-12 45.2 1.0 0.00017 21.9 0.1 2.9 2 0 0 2 2 2 2 C2 domain PH PF00169.29 OQS06124.1 - 0.0002 21.8 0.1 0.0006 20.3 0.1 1.9 1 0 0 1 1 1 1 PH domain HSBP1 PF06825.12 OQS06126.1 - 1e-19 70.1 5.6 7.2e-19 67.4 5.6 1.9 1 1 0 1 1 1 1 Heat shock factor binding protein 1 YvrJ PF12841.7 OQS06126.1 - 0.012 15.2 0.2 0.047 13.2 0.0 1.9 2 0 0 2 2 2 0 YvrJ protein family TPK_catalytic PF04263.16 OQS06126.1 - 0.058 13.4 0.1 0.074 13.1 0.1 1.1 1 0 0 1 1 1 0 Thiamin pyrophosphokinase, catalytic domain Laminin_I PF06008.14 OQS06126.1 - 0.083 12.6 1.3 0.92 9.2 0.5 2.0 1 1 0 2 2 2 0 Laminin Domain I Erythro-docking PF09277.11 OQS06126.1 - 0.092 12.7 0.0 1.5 8.8 0.1 2.1 2 0 0 2 2 2 0 Erythronolide synthase, docking DnaJ PF00226.31 OQS06127.1 - 8.2e-06 25.9 0.0 2.1e-05 24.6 0.0 1.7 1 0 0 1 1 1 1 DnaJ domain Pam16 PF03656.13 OQS06127.1 - 9.4e-05 22.4 0.1 0.00031 20.8 0.1 1.9 1 1 0 1 1 1 1 Pam16 TIP41 PF04176.13 OQS06127.1 - 0.053 13.0 0.0 0.067 12.7 0.0 1.1 1 0 0 1 1 1 0 TIP41-like family ATPase PF06745.13 OQS06127.1 - 0.16 11.3 0.0 0.27 10.5 0.0 1.4 2 0 0 2 2 2 0 KaiC RRN3 PF05327.11 OQS06128.1 - 3.3e-85 286.7 7.6 3.3e-85 286.7 7.6 2.7 1 1 1 2 2 2 1 RNA polymerase I specific transcription initiation factor RRN3 G-patch PF01585.23 OQS06128.1 - 4.9e-14 51.9 0.7 1e-13 50.9 0.7 1.6 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 OQS06128.1 - 1e-08 35.1 0.2 1e-08 35.1 0.2 2.2 2 0 0 2 2 2 1 G-patch domain Cwf_Cwc_15 PF04889.12 OQS06128.1 - 0.025 14.3 7.4 0.043 13.6 7.4 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Lycopene_cycl PF05834.12 OQS06128.1 - 0.1 11.6 0.2 0.24 10.4 0.0 1.6 2 0 0 2 2 2 0 Lycopene cyclase protein Macoilin PF09726.9 OQS06128.1 - 0.29 9.6 8.7 0.42 9.1 8.7 1.1 1 0 0 1 1 1 0 Macoilin family FAM60A PF15396.6 OQS06128.1 - 1.4 8.9 7.9 2.3 8.2 7.9 1.3 1 0 0 1 1 1 0 Protein Family FAM60A DALR_1 PF05746.15 OQS06128.1 - 4.9 7.4 12.2 4.7 7.4 0.4 3.8 2 1 2 4 4 4 0 DALR anticodon binding domain DUF262 PF03235.14 OQS06128.1 - 9.1 6.4 9.4 4.8 7.3 3.2 2.3 2 0 0 2 2 2 0 Protein of unknown function DUF262 EF-hand_7 PF13499.6 OQS06129.1 - 5.9e-10 39.5 0.8 0.0014 19.0 0.1 3.5 3 0 0 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.6 OQS06129.1 - 1e-08 34.4 0.6 0.0023 17.7 0.0 4.4 4 0 0 4 4 4 3 EF-hand domain EF-hand_1 PF00036.32 OQS06129.1 - 4.8e-07 28.9 0.1 0.0041 16.6 0.0 4.3 4 0 0 4 4 4 2 EF hand EF-hand_8 PF13833.6 OQS06129.1 - 0.016 15.0 1.4 6 6.8 0.0 3.3 4 0 0 4 4 4 0 EF-hand domain pair EF-hand_10 PF14788.6 OQS06129.1 - 0.034 14.0 0.2 0.64 9.9 0.1 2.9 2 0 0 2 2 2 0 EF hand Mst1_SARAH PF11629.8 OQS06129.1 - 0.11 12.6 2.5 27 5.0 0.3 3.8 4 0 0 4 4 4 0 C terminal SARAH domain of Mst1 DNA_pol3_a_NII PF11490.8 OQS06129.1 - 0.13 12.1 4.2 0.074 12.9 1.4 2.1 2 0 0 2 2 2 0 DNA polymerase III polC-type N-terminus II GPHH PF16905.5 OQS06129.1 - 0.14 12.0 0.0 0.84 9.5 0.0 2.3 2 0 0 2 2 2 0 Voltage-dependent L-type calcium channel, IQ-associated EF-hand_5 PF13202.6 OQS06129.1 - 0.14 11.7 0.5 17 5.1 0.0 3.3 4 0 0 4 4 4 0 EF hand TED_complement PF07678.14 OQS06130.1 - 0.036 13.1 0.0 0.045 12.8 0.0 1.0 1 0 0 1 1 1 0 A-macroglobulin TED domain Sod_Fe_N PF00081.22 OQS06132.1 - 1.8e-18 66.8 1.7 1.8e-18 66.8 1.7 2.6 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, alpha-hairpin domain TPR_2 PF07719.17 OQS06132.1 - 6.4e-06 25.9 14.6 0.00042 20.2 0.2 4.8 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_1 PF00515.28 OQS06132.1 - 0.00011 21.9 7.5 0.0067 16.2 0.3 3.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.6 OQS06132.1 - 0.021 15.0 5.3 0.19 12.1 0.2 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 OQS06132.1 - 0.076 13.9 0.5 0.076 13.9 0.5 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF4140 PF13600.6 OQS06132.1 - 0.28 11.6 0.0 0.28 11.6 0.0 3.6 2 1 1 3 3 3 0 N-terminal domain of unknown function (DUF4140) TPR_11 PF13414.6 OQS06132.1 - 1.9 8.2 8.5 1.4 8.7 0.6 3.6 2 1 1 3 3 3 0 TPR repeat ANAPC3 PF12895.7 OQS06132.1 - 3.5 7.9 12.8 0.12 12.7 0.7 3.3 2 1 1 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 OQS06132.1 - 4.3 8.2 13.5 0.24 12.1 1.1 4.6 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_9 PF13371.6 OQS06132.1 - 8.7 6.6 8.4 0.64 10.2 1.0 2.9 4 0 0 4 4 4 0 Tetratricopeptide repeat SRP40_C PF05022.12 OQS06134.1 - 8.3e-23 81.0 0.6 8.3e-23 81.0 0.6 2.2 2 0 0 2 2 2 1 SRP40, C-terminal domain cNMP_binding PF00027.29 OQS06135.1 - 1.4e-38 130.9 0.1 3.2e-20 72.0 0.0 3.5 3 1 0 3 3 3 2 Cyclic nucleotide-binding domain Mito_carr PF00153.27 OQS06135.1 - 7e-36 122.0 0.3 8.9e-21 73.6 0.1 3.4 3 0 0 3 3 3 3 Mitochondrial carrier protein Peptidase_C92 PF05708.12 OQS06135.1 - 1.9e-05 24.9 0.0 0.017 15.3 0.0 2.9 2 1 0 2 2 2 2 Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family Thioredoxin_8 PF13905.6 OQS06136.1 - 3.7e-27 94.5 0.0 4.6e-27 94.2 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin-like AhpC-TSA PF00578.21 OQS06136.1 - 4e-07 30.0 0.0 5.3e-07 29.6 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin PF00085.20 OQS06136.1 - 1.3e-06 28.3 0.0 1.5e-05 24.9 0.0 2.0 2 0 0 2 2 2 1 Thioredoxin Redoxin PF08534.10 OQS06136.1 - 2.5e-05 24.0 0.0 3.4e-05 23.6 0.0 1.1 1 0 0 1 1 1 1 Redoxin Thioredoxin_9 PF14595.6 OQS06136.1 - 2.6e-05 24.0 0.0 5e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 OQS06136.1 - 3.9e-05 24.1 0.0 5.3e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like domain DUF953 PF06110.11 OQS06136.1 - 0.0037 16.9 0.1 0.005 16.4 0.1 1.2 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF953) Thioredoxin_7 PF13899.6 OQS06136.1 - 0.013 15.7 0.1 0.056 13.6 0.1 1.9 2 0 0 2 2 2 0 Thioredoxin-like ELK PF03789.13 OQS06136.1 - 0.14 12.3 1.2 0.24 11.5 1.2 1.3 1 0 0 1 1 1 0 ELK domain SCO1-SenC PF02630.14 OQS06136.1 - 0.14 12.1 0.0 0.2 11.5 0.0 1.2 1 0 0 1 1 1 0 SCO1/SenC Kinesin PF00225.23 OQS06137.1 - 4.3e-110 367.7 0.0 7.7e-110 366.9 0.0 1.4 1 0 0 1 1 1 1 Kinesin motor domain TANGO2 PF05742.12 OQS06137.1 - 6.6e-45 154.1 0.3 2.5e-44 152.2 0.0 2.1 2 0 0 2 2 2 1 Transport and Golgi organisation 2 DEAD PF00270.29 OQS06137.1 - 4.1e-42 143.9 0.1 4.1e-42 143.9 0.1 2.8 3 0 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OQS06137.1 - 2.6e-28 98.6 1.1 2.6e-27 95.4 0.5 2.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Microtub_bd PF16796.5 OQS06137.1 - 6.4e-24 84.6 0.0 2e-23 83.0 0.0 1.9 1 0 0 1 1 1 1 Microtubule binding ResIII PF04851.15 OQS06137.1 - 1.6e-05 25.0 1.7 0.0042 17.1 0.0 3.1 3 0 0 3 3 3 2 Type III restriction enzyme, res subunit AAA_22 PF13401.6 OQS06137.1 - 0.054 13.8 0.0 24 5.2 0.0 3.3 3 0 0 3 3 3 0 AAA domain Kinesin_assoc PF16183.5 OQS06137.1 - 4.7 7.3 8.2 5.5 7.1 5.8 2.2 2 0 0 2 2 2 0 Kinesin-associated PH PF00169.29 OQS06138.1 - 2.8e-10 40.6 0.2 1.8e-09 38.0 0.0 2.3 3 0 0 3 3 3 1 PH domain DUF5089 PF17002.5 OQS06138.1 - 0.00056 19.8 7.0 0.00099 19.0 7.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF5089) V-SNARE_C PF12352.8 OQS06138.1 - 0.025 14.9 4.0 0.2 12.0 0.0 2.5 2 1 0 2 2 2 0 Snare region anchored in the vesicle membrane C-terminus PH_11 PF15413.6 OQS06138.1 - 0.028 14.8 1.1 0.028 14.8 1.1 2.3 2 1 0 2 2 2 0 Pleckstrin homology domain PH_8 PF15409.6 OQS06138.1 - 0.28 11.5 1.4 0.46 10.8 0.2 2.0 2 0 0 2 2 2 0 Pleckstrin homology domain SNARE PF05739.19 OQS06138.1 - 0.35 10.9 6.4 3.9 7.6 0.4 2.8 2 0 0 2 2 2 0 SNARE domain DUF4407 PF14362.6 OQS06138.1 - 1.1 8.6 10.4 31 3.8 10.4 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) DUF948 PF06103.11 OQS06138.1 - 2.2 8.6 7.4 0.48 10.7 1.5 2.2 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) CHDCT2 PF08074.11 OQS06138.1 - 2.2 8.4 5.7 2.5 8.2 0.8 2.2 2 0 0 2 2 2 0 CHDCT2 (NUC038) domain DUF745 PF05335.13 OQS06138.1 - 2.9 7.6 9.1 2.5 7.8 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF745) Spc7 PF08317.11 OQS06138.1 - 3.2 6.6 10.1 0.66 8.8 4.1 2.1 2 0 0 2 2 2 0 Spc7 kinetochore protein NPV_P10 PF05531.12 OQS06138.1 - 3.5 8.2 7.8 46 4.6 5.2 2.9 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein ATG16 PF08614.11 OQS06138.1 - 4.4 7.5 14.1 0.62 10.3 8.6 2.0 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) Tropomyosin_1 PF12718.7 OQS06138.1 - 6.4 6.9 13.6 1.4 9.1 6.7 2.3 2 0 0 2 2 2 0 Tropomyosin like WD40_3 PF15911.5 OQS06139.1 - 1.5e-16 60.1 0.0 1.1e-14 54.2 0.0 2.9 2 0 0 2 2 2 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OQS06139.1 - 1.2e-12 48.0 0.6 0.0075 16.6 0.1 4.9 2 1 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Clathrin PF00637.20 OQS06139.1 - 9.7e-07 28.8 2.3 0.61 10.0 0.0 4.2 3 1 1 4 4 4 2 Region in Clathrin and VPS TPR_14 PF13428.6 OQS06139.1 - 3.6e-05 24.2 12.6 1.4 9.9 0.7 7.3 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_7 PF13176.6 OQS06139.1 - 0.0064 16.4 11.5 20 5.5 0.1 7.2 7 0 0 7 7 7 0 Tetratricopeptide repeat WD40 PF00400.32 OQS06139.1 - 0.0078 17.1 0.6 11 7.1 0.0 5.3 5 0 0 5 5 4 0 WD domain, G-beta repeat eIF2A PF08662.11 OQS06139.1 - 0.017 15.0 0.1 0.38 10.6 0.0 2.9 2 1 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A Coatomer_WDAD PF04053.14 OQS06139.1 - 0.019 14.0 12.7 0.5 9.3 3.5 4.5 5 0 0 5 5 5 0 Coatomer WD associated region PALB2_WD40 PF16756.5 OQS06139.1 - 0.021 13.8 0.2 0.052 12.5 0.0 1.7 2 0 0 2 2 2 0 Partner and localizer of BRCA2 WD40 domain Rad50_zn_hook PF04423.14 OQS06139.1 - 0.032 14.1 0.2 0.17 11.7 0.0 2.4 2 0 0 2 2 1 0 Rad50 zinc hook motif zf-ribbon_3 PF13248.6 OQS06139.1 - 0.036 13.5 5.5 0.35 10.3 0.1 3.5 3 0 0 3 3 3 0 zinc-ribbon domain Rtf2 PF04641.12 OQS06139.1 - 0.12 11.7 0.3 0.25 10.7 0.3 1.4 1 0 0 1 1 1 0 Rtf2 RING-finger Mcl1_mid PF12341.8 OQS06139.1 - 0.16 11.3 0.0 5 6.4 0.0 3.0 3 1 0 3 3 3 0 Minichromosome loss protein, Mcl1, middle region DUF1923 PF09083.10 OQS06139.1 - 0.17 11.6 0.0 0.52 10.0 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF1923) TPR_8 PF13181.6 OQS06139.1 - 0.36 11.2 18.1 32 5.1 0.1 8.0 7 1 1 8 8 8 0 Tetratricopeptide repeat Prok-RING_4 PF14447.6 OQS06139.1 - 0.37 10.7 7.4 9.1 6.2 2.6 3.2 2 1 1 3 3 3 0 Prokaryotic RING finger family 4 zf-Di19 PF05605.12 OQS06139.1 - 0.43 10.9 11.9 0.27 11.6 2.4 3.0 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding TPR_19 PF14559.6 OQS06139.1 - 0.48 11.0 15.0 50 4.5 0.1 6.2 6 1 0 6 6 6 0 Tetratricopeptide repeat DZR PF12773.7 OQS06139.1 - 0.51 10.4 6.1 5.3 7.1 6.1 2.4 1 1 0 1 1 1 0 Double zinc ribbon Elf1 PF05129.13 OQS06139.1 - 1.2 9.2 3.5 0.83 9.7 0.2 2.5 2 0 0 2 2 2 0 Transcription elongation factor Elf1 like TPR_2 PF07719.17 OQS06139.1 - 4.4 7.7 30.6 17 5.8 0.5 8.5 8 1 1 9 9 8 0 Tetratricopeptide repeat Peptidase_M76 PF09768.9 OQS06140.1 - 4.4e-55 186.1 8.0 5e-55 185.9 8.0 1.0 1 0 0 1 1 1 1 Peptidase M76 family SprT-like PF10263.9 OQS06140.1 - 0.0024 17.7 0.1 0.0033 17.3 0.1 1.3 1 0 0 1 1 1 1 SprT-like family Peptidase_M15_3 PF08291.11 OQS06140.1 - 0.033 14.3 0.0 0.11 12.6 0.0 1.8 2 0 0 2 2 2 0 Peptidase M15 CPBP PF02517.16 OQS06141.1 - 2.9e-05 24.4 10.2 2.9e-05 24.4 10.2 2.4 2 1 0 2 2 2 1 CPBP intramembrane metalloprotease RPN1_RPN2_N PF17781.1 OQS06142.1 - 7.7e-113 377.0 0.0 1.2e-112 376.3 0.0 1.3 1 0 0 1 1 1 1 RPN1/RPN2 N-terminal domain RPN1_C PF18051.1 OQS06142.1 - 1.8e-30 104.7 0.0 4.4e-30 103.5 0.0 1.7 1 0 0 1 1 1 1 26S proteasome non-ATPase regulatory subunit RPN1 C-terminal PC_rep PF01851.22 OQS06142.1 - 8.3e-26 89.1 25.3 7.9e-05 22.9 0.1 9.7 10 0 0 10 10 10 7 Proteasome/cyclosome repeat HEAT_2 PF13646.6 OQS06142.1 - 1.1e-07 32.2 0.7 0.024 15.0 0.0 4.0 4 0 0 4 4 4 2 HEAT repeats IFRD PF05004.13 OQS06142.1 - 0.046 12.8 3.5 1.3 8.0 1.4 2.9 1 1 1 2 2 2 0 Interferon-related developmental regulator (IFRD) ADP_ribosyl_GH PF03747.14 OQS06142.1 - 1.3 8.7 5.3 0.66 9.7 0.2 2.6 2 1 0 2 2 2 0 ADP-ribosylglycohydrolase Complex1_LYR PF05347.15 OQS06143.1 - 2.8e-10 40.1 0.4 6.2e-10 39.0 0.4 1.5 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 OQS06143.1 - 2e-05 25.2 1.5 3.7e-05 24.4 1.5 1.7 1 1 0 1 1 1 1 Complex1_LYR-like Complex1_LYR_1 PF13232.6 OQS06143.1 - 0.0025 18.4 0.1 0.004 17.7 0.1 1.5 1 0 0 1 1 1 1 Complex1_LYR-like CIDE-N PF02017.15 OQS06143.1 - 0.0038 17.2 0.0 1.1 9.4 0.1 2.2 2 0 0 2 2 2 2 CIDE-N domain DSPc PF00782.20 OQS06144.1 - 2.7e-22 79.0 0.0 5.2e-22 78.1 0.0 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 OQS06144.1 - 0.043 13.4 0.0 0.092 12.3 0.0 1.5 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Mito_carr PF00153.27 OQS06145.1 - 5.3e-64 212.2 2.0 1.3e-21 76.3 0.1 3.0 2 1 1 3 3 3 3 Mitochondrial carrier protein CLASP_N PF12348.8 OQS06146.1 - 1.8e-06 27.7 4.8 3.6e-06 26.7 3.8 1.8 1 1 0 1 1 1 1 CLASP N terminal SPG48 PF14764.6 OQS06146.1 - 0.0035 17.8 5.4 0.84 10.1 0.0 2.4 2 0 0 2 2 2 2 AP-5 complex subunit, vesicle trafficking EphA2_TM PF14575.6 OQS06147.1 - 0.021 15.7 0.1 7.9 7.4 0.0 2.8 2 1 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Shisa PF13908.6 OQS06147.1 - 0.045 14.0 4.7 0.048 13.9 0.1 2.6 2 1 0 2 2 2 0 Wnt and FGF inhibitory regulator DUF1614 PF07758.11 OQS06147.1 - 0.053 13.5 0.1 3.4 7.7 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1614) DUF4690 PF15756.5 OQS06147.1 - 1.1 9.9 5.7 6 7.5 0.1 3.6 3 0 0 3 3 3 0 Small Novel Rich in Cartilage AAA PF00004.29 OQS06148.1 - 4.7e-43 146.8 0.0 7.6e-43 146.1 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 OQS06148.1 - 2e-11 43.5 0.0 4.2e-11 42.5 0.0 1.5 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 OQS06148.1 - 7.8e-07 29.6 0.6 0.00017 22.1 0.1 2.6 1 1 1 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 OQS06148.1 - 4.7e-06 26.9 0.6 0.0002 21.7 0.6 2.4 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.14 OQS06148.1 - 7.4e-06 26.0 0.0 2.3e-05 24.4 0.0 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.17 OQS06148.1 - 7.7e-06 25.7 0.0 2.7e-05 24.0 0.0 1.8 2 0 0 2 2 2 1 IstB-like ATP binding protein DUF815 PF05673.13 OQS06148.1 - 3.8e-05 23.0 0.0 7.7e-05 22.0 0.0 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF815) AAA_2 PF07724.14 OQS06148.1 - 0.00023 21.3 0.0 0.0005 20.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_33 PF13671.6 OQS06148.1 - 0.00024 21.3 0.0 0.00056 20.1 0.0 1.7 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.12 OQS06148.1 - 0.00029 20.6 0.0 0.00069 19.4 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_7 PF12775.7 OQS06148.1 - 0.00073 19.1 0.0 0.0033 17.0 0.0 2.0 2 1 0 2 2 2 1 P-loop containing dynein motor region TIP49 PF06068.13 OQS06148.1 - 0.0011 18.2 0.1 0.0018 17.6 0.1 1.2 1 0 0 1 1 1 1 TIP49 P-loop domain Sigma54_activat PF00158.26 OQS06148.1 - 0.01 15.6 0.0 0.031 14.0 0.0 1.8 1 1 0 1 1 1 0 Sigma-54 interaction domain TsaE PF02367.17 OQS06148.1 - 0.01 15.8 0.0 0.024 14.6 0.0 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_25 PF13481.6 OQS06148.1 - 0.011 15.3 0.1 0.78 9.3 0.0 2.5 2 0 0 2 2 2 0 AAA domain PhoH PF02562.16 OQS06148.1 - 0.014 14.9 0.0 0.027 13.9 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein AAA_18 PF13238.6 OQS06148.1 - 0.014 16.0 0.0 0.038 14.5 0.0 1.9 1 1 0 1 1 1 0 AAA domain FtsH_ext PF06480.15 OQS06148.1 - 0.019 15.3 0.1 0.093 13.1 0.1 2.0 2 0 0 2 2 2 0 FtsH Extracellular AAA_14 PF13173.6 OQS06148.1 - 0.024 14.7 0.0 0.056 13.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 OQS06148.1 - 0.048 13.0 0.0 0.11 11.9 0.0 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Methylase_S PF01420.19 OQS06148.1 - 0.062 13.5 0.0 0.11 12.7 0.0 1.3 1 0 0 1 1 1 0 Type I restriction modification DNA specificity domain AAA_28 PF13521.6 OQS06148.1 - 0.085 13.1 0.0 0.15 12.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 OQS06148.1 - 0.094 12.4 0.0 0.28 10.9 0.0 1.8 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 OQS06148.1 - 0.13 12.1 0.2 0.51 10.2 0.2 2.0 1 1 0 1 1 1 0 NACHT domain Cytidylate_kin PF02224.18 OQS06148.1 - 0.14 11.8 0.1 0.36 10.5 0.1 1.7 1 0 0 1 1 1 0 Cytidylate kinase RNA_helicase PF00910.22 OQS06148.1 - 0.15 12.4 0.0 0.39 11.1 0.0 1.8 1 0 0 1 1 1 0 RNA helicase AAA_6 PF12774.7 OQS06148.1 - 0.22 10.4 0.4 5 6.0 0.1 2.2 2 0 0 2 2 2 0 Hydrolytic ATP binding site of dynein motor region TMEM171 PF15471.6 OQS06149.1 - 0.0089 15.0 0.1 0.015 14.3 0.1 1.5 1 1 0 1 1 1 1 Transmembrane protein family 171 EphA2_TM PF14575.6 OQS06149.1 - 0.065 14.1 0.0 0.11 13.4 0.0 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF5367 PF17329.2 OQS06149.1 - 0.072 13.2 0.0 0.3 11.2 0.0 1.8 2 0 0 2 2 2 0 Family of unknown function (DUF5367) DUF1180 PF06679.12 OQS06149.1 - 0.091 13.2 0.1 0.091 13.2 0.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) Protocadherin PF08374.11 OQS06149.1 - 0.18 11.8 0.1 0.18 11.8 0.1 1.6 2 0 0 2 2 2 0 Protocadherin Glucan_synthase PF02364.15 OQS06150.1 - 2.1e-187 624.9 10.3 5.3e-168 560.8 6.3 2.3 1 1 1 2 2 2 2 1,3-beta-glucan synthase component Sugar_tr PF00083.24 OQS06150.1 - 9.8e-27 93.9 26.1 9.8e-27 93.9 26.1 2.5 3 0 0 3 3 3 1 Sugar (and other) transporter FKS1_dom1 PF14288.6 OQS06150.1 - 2.2e-23 83.0 3.7 1e-22 80.8 2.7 2.6 2 1 0 2 2 2 1 1,3-beta-glucan synthase subunit FKS1, domain-1 PK PF00224.21 OQS06151.1 - 1.8e-129 431.6 2.4 1.8e-129 431.6 2.4 1.5 2 0 0 2 2 2 1 Pyruvate kinase, barrel domain PK_C PF02887.16 OQS06151.1 - 1.4e-23 83.4 2.1 2.4e-23 82.6 0.6 2.2 2 1 0 2 2 2 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.14 OQS06151.1 - 0.0064 15.6 0.1 0.021 14.0 0.0 1.9 1 1 1 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family DUF3829 PF12889.7 OQS06151.1 - 0.011 15.2 0.1 0.02 14.4 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3829) PASTA PF03793.19 OQS06151.1 - 0.028 14.3 0.4 0.15 11.9 0.0 2.4 3 0 0 3 3 3 0 PASTA domain AA_permease PF00324.21 OQS06152.1 - 4.1e-47 160.9 36.8 5.1e-47 160.6 36.8 1.1 1 0 0 1 1 1 1 Amino acid permease SLC12 PF03522.15 OQS06152.1 - 7.1e-33 114.3 11.3 5.9e-24 84.9 0.2 3.4 1 1 1 3 3 3 2 Solute carrier family 12 DUF2842 PF11003.8 OQS06152.1 - 2.2 8.6 6.1 8.7 6.7 1.8 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2842) Ank_2 PF12796.7 OQS06153.1 - 4.8e-16 59.1 11.8 3.4e-07 30.8 1.6 3.4 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQS06153.1 - 8.5e-10 39.0 5.0 0.00041 20.9 0.0 5.0 2 2 4 6 6 6 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 OQS06153.1 - 8.8e-10 38.6 8.3 0.23 11.8 0.2 6.3 1 1 6 7 7 7 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQS06153.1 - 2.3e-07 30.6 2.6 1.4 9.7 0.1 5.6 5 0 0 5 5 5 2 Ankyrin repeat Ank PF00023.30 OQS06153.1 - 0.00037 20.8 1.3 18 6.0 0.0 4.9 3 1 2 5 5 5 1 Ankyrin repeat DUF249 PF03158.13 OQS06153.1 - 0.047 13.4 4.8 0.072 12.8 1.6 2.7 2 1 0 2 2 2 0 Multigene family 530 protein FHA PF00498.26 OQS06154.1 - 2.8e-15 56.4 0.0 5.4e-15 55.5 0.0 1.5 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 OQS06154.1 - 1.4e-07 31.7 0.0 2.6e-07 30.9 0.0 1.3 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain IFRD PF05004.13 OQS06155.1 - 0.16 11.0 0.3 0.34 10.0 0.2 1.5 1 1 0 1 1 1 0 Interferon-related developmental regulator (IFRD) RNA_lig_T4_1 PF09511.10 OQS06156.1 - 5.6e-05 23.1 0.0 0.00014 21.8 0.0 1.6 1 1 0 1 1 1 1 RNA ligase DUF2518 PF10726.9 OQS06157.1 - 0.047 13.3 0.1 0.059 13.0 0.1 1.1 1 0 0 1 1 1 0 Protein of function (DUF2518) PRIMA1 PF16101.5 OQS06157.1 - 9 6.4 7.5 0.28 11.2 0.3 1.8 1 1 1 2 2 2 0 Proline-rich membrane anchor 1 PUF PF00806.19 OQS06158.1 - 2.3e-48 159.2 2.8 3.1e-06 26.6 0.0 8.4 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat zf-CCCH_4 PF18044.1 OQS06158.1 - 4.2e-08 32.8 5.5 1.1e-07 31.5 5.5 1.8 1 0 0 1 1 1 1 CCCH-type zinc finger zf-CCCH PF00642.24 OQS06158.1 - 2e-05 24.4 4.8 4.5e-05 23.3 4.8 1.5 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 OQS06158.1 - 0.00033 20.6 8.8 0.00069 19.6 8.8 1.6 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH_3 PF15663.5 OQS06158.1 - 0.00036 20.7 0.1 0.00084 19.5 0.1 1.6 1 0 0 1 1 1 1 Zinc-finger containing family Torus PF16131.5 OQS06158.1 - 0.00058 20.5 0.2 0.0013 19.4 0.2 1.6 1 0 0 1 1 1 1 Torus domain zf-CCCH_2 PF14608.6 OQS06158.1 - 0.085 13.4 6.4 0.22 12.0 6.4 1.8 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger LuxT_C PF18285.1 OQS06158.1 - 0.12 12.9 0.2 1.2 9.7 0.0 2.7 3 0 0 3 3 3 0 Tetracycline repressor LuxT C-terminal domain Ank_4 PF13637.6 OQS06159.1 - 2.2e-17 63.2 2.1 3.1e-11 43.6 0.1 3.1 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 OQS06159.1 - 3.3e-14 53.2 0.1 1.7e-08 34.9 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OQS06159.1 - 1.9e-11 43.1 0.4 0.00028 21.1 0.0 3.7 3 0 0 3 3 3 3 Ankyrin repeat Ank PF00023.30 OQS06159.1 - 5.7e-09 36.0 0.5 0.0025 18.2 0.0 3.5 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 OQS06159.1 - 4.7e-08 33.1 0.1 4.3e-05 23.7 0.1 3.6 2 1 2 4 4 4 3 Ankyrin repeats (many copies) V_ATPase_I PF01496.19 OQS06159.1 - 1.6 6.6 9.8 1.9 6.3 9.8 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family CBFD_NFYB_HMF PF00808.23 OQS06160.1 - 3.4e-26 91.3 0.1 4.4e-26 90.9 0.1 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 OQS06160.1 - 0.00087 19.7 0.0 0.0015 18.9 0.0 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 OQS06160.1 - 0.0048 17.0 0.0 0.0057 16.8 0.0 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold Bromo_TP PF07524.13 OQS06160.1 - 0.013 15.5 0.0 0.026 14.5 0.0 1.5 1 1 0 1 1 1 0 Bromodomain associated TFIID_20kDa PF03847.13 OQS06160.1 - 0.028 14.9 0.5 0.76 10.3 0.1 2.2 2 0 0 2 2 2 0 Transcription initiation factor TFIID subunit A TFIID-18kDa PF02269.16 OQS06160.1 - 0.049 13.7 0.0 0.061 13.4 0.0 1.3 1 0 0 1 1 1 0 Transcription initiation factor IID, 18kD subunit MAPEG PF01124.18 OQS06161.1 - 1.6e-17 63.6 1.6 2.2e-17 63.2 1.6 1.1 1 0 0 1 1 1 1 MAPEG family Spermine_synth PF01564.17 OQS06162.1 - 1.2e-65 220.4 0.0 2.4e-65 219.5 0.0 1.5 1 0 0 1 1 1 1 Spermine/spermidine synthase domain Spermine_synt_N PF17284.2 OQS06162.1 - 9.3e-21 73.5 0.1 1.6e-20 72.7 0.1 1.4 1 0 0 1 1 1 1 Spermidine synthase tetramerisation domain Methyltransf_25 PF13649.6 OQS06162.1 - 0.00045 20.9 0.0 0.002 18.8 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_24 PF13578.6 OQS06162.1 - 0.0021 19.1 0.0 0.0052 17.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OQS06162.1 - 0.0021 18.8 0.0 0.012 16.4 0.0 2.3 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_30 PF05430.11 OQS06162.1 - 0.03 14.2 0.0 0.05 13.5 0.0 1.3 1 0 0 1 1 1 0 S-adenosyl-L-methionine-dependent methyltransferase Vps52 PF04129.12 OQS06163.1 - 1.4e-129 433.1 8.9 2e-129 432.7 8.9 1.2 1 0 0 1 1 1 1 Vps52 / Sac2 family Sec3_C PF09763.9 OQS06163.1 - 1.1e-05 24.1 9.3 1.1e-05 24.1 9.3 2.6 1 1 0 2 2 2 1 Exocyst complex component Sec3 COG2 PF06148.11 OQS06163.1 - 0.0025 17.9 3.3 0.0025 17.9 3.3 2.3 3 0 0 3 3 3 1 COG (conserved oligomeric Golgi) complex component, COG2 baeRF_family11 PF18855.1 OQS06163.1 - 0.0078 16.5 0.7 0.091 13.1 0.0 2.5 2 0 0 2 2 2 1 Bacterial archaeo-eukaryotic release factor family 11 baeRF_family8 PF18851.1 OQS06163.1 - 0.019 15.0 1.7 0.43 10.7 0.2 2.6 1 1 0 2 2 2 0 Bacterial archaeo-eukaryotic release factor family 8 DUF5405 PF17399.2 OQS06163.1 - 0.069 13.4 0.2 8.2 6.8 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF5405) GYF_2 PF14237.6 OQS06164.1 - 2.5e-17 62.4 2.0 3e-08 33.3 0.1 2.9 2 0 0 2 2 2 2 GYF domain 2 RRM_1 PF00076.22 OQS06164.1 - 4.7e-12 45.5 0.0 8.5e-05 22.3 0.0 3.0 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) GYF PF02213.16 OQS06164.1 - 0.017 14.8 0.3 6.8 6.4 0.0 2.8 2 0 0 2 2 2 0 GYF domain RRM_7 PF16367.5 OQS06164.1 - 0.02 15.0 0.0 0.045 13.9 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif RRM_occluded PF16842.5 OQS06164.1 - 0.028 14.3 0.0 0.074 12.9 0.0 1.6 1 0 0 1 1 1 0 Occluded RNA-recognition motif SH2_2 PF14633.6 OQS06165.1 - 2.9e-54 183.7 0.1 2.9e-54 183.7 0.1 2.3 3 0 0 3 3 3 1 SH2 domain HHH_7 PF14635.6 OQS06165.1 - 4.9e-18 65.4 0.6 1.1e-17 64.2 0.1 1.9 2 0 0 2 2 2 1 Helix-hairpin-helix motif HTH_44 PF14641.6 OQS06165.1 - 1.1e-11 45.2 2.2 1.1e-11 45.1 0.1 2.1 2 0 0 2 2 2 1 Helix-turn-helix DNA-binding domain of SPT6 YqgF PF14639.6 OQS06165.1 - 3e-10 40.1 0.0 7.1e-10 38.9 0.0 1.7 1 0 0 1 1 1 1 Holliday-junction resolvase-like of SPT6 SPT6_acidic PF14632.6 OQS06165.1 - 5e-09 36.6 31.6 5e-09 36.6 31.6 5.8 3 1 1 5 5 5 1 Acidic N-terminal SPT6 Tex_N PF09371.10 OQS06165.1 - 6.4e-08 32.5 0.0 8e-06 25.7 0.0 2.7 1 1 0 1 1 1 1 Tex-like protein N-terminal domain HHH_9 PF17674.1 OQS06165.1 - 4.5e-06 27.5 1.6 0.00065 20.6 1.6 3.4 1 1 0 1 1 1 1 HHH domain Tex_YqgF PF16921.5 OQS06165.1 - 0.0005 20.5 0.0 0.0012 19.3 0.0 1.6 1 0 0 1 1 1 1 Tex protein YqgF-like domain zf-CCCH PF00642.24 OQS06167.1 - 3.1e-13 49.3 17.1 1.8e-07 30.8 2.3 3.1 3 0 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RRM_1 PF00076.22 OQS06167.1 - 0.00022 21.0 0.1 0.00048 19.9 0.1 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCCH_3 PF15663.5 OQS06167.1 - 0.0067 16.6 2.8 2.4 8.4 0.4 2.4 2 0 0 2 2 2 2 Zinc-finger containing family zf_CCCH_4 PF18345.1 OQS06167.1 - 0.007 16.4 21.7 0.0075 16.3 2.3 2.9 3 0 0 3 3 3 2 Zinc finger domain Torus PF16131.5 OQS06167.1 - 0.011 16.4 11.7 0.16 12.7 0.3 2.9 2 1 1 3 3 3 0 Torus domain DUF1509 PF07420.11 OQS06167.1 - 1.3 7.9 14.3 2 7.3 14.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1509) Transformer PF06495.11 OQS06167.1 - 4 7.5 21.1 6.2 6.9 21.1 1.3 1 0 0 1 1 1 0 Fruit fly transformer protein Arm PF00514.23 OQS06168.1 - 7.9e-07 28.9 0.5 0.095 12.8 0.0 3.3 3 0 0 3 3 3 2 Armadillo/beta-catenin-like repeat HEAT PF02985.22 OQS06168.1 - 0.025 14.8 0.8 0.52 10.7 0.0 3.4 4 0 0 4 4 4 0 HEAT repeat Uso1_p115_head PF04869.14 OQS06168.1 - 0.028 13.6 0.9 0.062 12.4 0.1 1.9 2 0 0 2 2 2 0 Uso1 / p115 like vesicle tethering protein, head region HEAT_2 PF13646.6 OQS06168.1 - 0.055 13.9 0.1 0.18 12.2 0.1 2.0 1 1 0 1 1 1 0 HEAT repeats HEAT_EZ PF13513.6 OQS06168.1 - 0.18 12.3 1.5 2.1 8.9 0.0 3.0 2 1 1 3 3 3 0 HEAT-like repeat fn3 PF00041.21 OQS06169.1 - 3.1e-08 33.9 17.2 0.018 15.4 0.1 9.7 10 0 0 10 10 10 1 Fibronectin type III domain Pur_ac_phosph_N PF16656.5 OQS06169.1 - 2.9e-05 24.5 19.2 3.4 8.3 0.5 8.2 9 0 0 9 9 9 2 Purple acid Phosphatase, N-terminal domain cEGF PF12662.7 OQS06169.1 - 0.1 12.5 14.5 0.39 10.7 0.8 3.6 3 0 0 3 3 3 0 Complement Clr-like EGF-like hGDE_N PF14699.6 OQS06169.1 - 0.13 12.4 0.1 6.4 7.0 0.0 3.4 3 1 0 3 3 3 0 N-terminal domain from the human glycogen debranching enzyme Plasmod_Pvs28 PF06247.11 OQS06169.1 - 0.32 11.3 4.9 0.64 10.4 2.3 2.5 2 0 0 2 2 2 0 Pvs28 EGF domain EGF_MSP1_1 PF12946.7 OQS06169.1 - 0.8 9.8 6.2 0.38 10.8 1.3 2.9 2 0 0 2 2 2 0 MSP1 EGF domain 1 TPR_1 PF00515.28 OQS06170.1 - 7.6e-32 107.8 37.9 2.2e-06 27.2 2.1 10.4 11 1 0 11 11 10 6 Tetratricopeptide repeat TPR_2 PF07719.17 OQS06170.1 - 8.4e-30 100.5 33.8 2.9e-06 27.0 0.0 10.0 11 0 0 11 11 9 7 Tetratricopeptide repeat TPR_11 PF13414.6 OQS06170.1 - 9.4e-25 86.0 25.9 9.6e-06 25.2 1.8 9.1 6 3 3 9 9 9 7 TPR repeat DnaJ PF00226.31 OQS06170.1 - 2.6e-23 81.9 5.1 2.6e-23 81.9 5.1 2.1 2 0 0 2 2 2 1 DnaJ domain TPR_16 PF13432.6 OQS06170.1 - 1.1e-19 70.8 23.0 3.8e-06 27.5 0.1 6.8 6 1 0 6 6 6 4 Tetratricopeptide repeat TPR_19 PF14559.6 OQS06170.1 - 2.4e-19 69.6 21.1 3.6e-09 37.0 0.1 6.0 3 3 3 6 6 6 4 Tetratricopeptide repeat TPR_8 PF13181.6 OQS06170.1 - 9e-18 62.9 30.5 0.0099 16.0 0.0 9.8 10 1 0 10 10 9 5 Tetratricopeptide repeat TPR_14 PF13428.6 OQS06170.1 - 1e-15 57.0 23.1 0.0037 18.0 0.0 8.6 4 3 5 9 9 9 4 Tetratricopeptide repeat TPR_17 PF13431.6 OQS06170.1 - 1.5e-14 53.2 13.1 0.1 13.1 1.9 7.1 7 0 0 7 7 6 4 Tetratricopeptide repeat TPR_12 PF13424.6 OQS06170.1 - 6.3e-11 42.4 26.8 0.0014 18.9 0.7 6.9 5 2 1 6 6 6 3 Tetratricopeptide repeat TPR_7 PF13176.6 OQS06170.1 - 9.6e-10 37.8 13.0 0.43 10.7 0.0 7.5 8 0 0 8 8 7 2 Tetratricopeptide repeat TPR_9 PF13371.6 OQS06170.1 - 2.3e-07 30.9 12.8 0.0073 16.4 0.2 6.1 3 2 4 7 7 6 2 Tetratricopeptide repeat ANAPC3 PF12895.7 OQS06170.1 - 0.00011 22.3 0.3 0.00011 22.3 0.3 5.0 4 2 2 6 6 6 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 OQS06170.1 - 0.00015 22.2 27.1 0.0041 17.7 0.0 7.3 9 0 0 9 9 6 1 Tetratricopeptide repeat SRP_TPR_like PF17004.5 OQS06170.1 - 0.0011 19.0 0.1 0.0011 19.0 0.1 4.2 3 1 1 4 4 4 1 Putative TPR-like repeat FAT PF02259.23 OQS06170.1 - 0.0015 17.8 1.1 0.0015 17.8 1.1 2.3 1 1 1 2 2 2 1 FAT domain BTAD PF03704.17 OQS06170.1 - 0.0017 18.8 17.2 0.034 14.6 0.2 4.9 2 1 0 3 3 3 1 Bacterial transcriptional activator domain Fis1_TPR_C PF14853.6 OQS06170.1 - 0.002 18.2 4.2 0.73 10.0 0.0 4.0 5 0 0 5 5 3 2 Fis1 C-terminal tetratricopeptide repeat HEAT_2 PF13646.6 OQS06170.1 - 0.0059 17.0 0.0 0.017 15.5 0.0 1.8 1 0 0 1 1 1 1 HEAT repeats NARP1 PF12569.8 OQS06170.1 - 0.017 14.0 27.6 0.13 11.1 0.3 5.4 1 1 5 6 6 6 0 NMDA receptor-regulated protein 1 DUF3856 PF12968.7 OQS06170.1 - 0.15 12.1 10.4 1.3 9.0 1.5 5.7 4 3 1 5 5 5 0 Domain of Unknown Function (DUF3856) Alkyl_sulf_dimr PF14863.6 OQS06170.1 - 0.18 12.3 9.5 15 6.0 0.1 4.6 2 1 3 5 5 4 0 Alkyl sulfatase dimerisation MAS20 PF02064.15 OQS06170.1 - 0.27 11.3 0.1 0.27 11.3 0.1 4.0 4 1 0 4 4 4 0 MAS20 protein import receptor MIT PF04212.18 OQS06170.1 - 0.34 11.0 14.2 12 6.1 0.1 6.4 5 2 2 7 7 7 0 MIT (microtubule interacting and transport) domain CHORD PF04968.12 OQS06171.1 - 0.00014 22.5 3.0 0.00033 21.3 3.0 1.6 1 0 0 1 1 1 1 CHORD Fmp27_GFWDK PF10347.9 OQS06171.1 - 0.054 13.6 0.5 0.13 12.4 0.4 1.7 1 1 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain ATG16 PF08614.11 OQS06171.1 - 1.3 9.2 58.9 2 8.6 24.9 4.1 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) Med3 PF11593.8 OQS06171.1 - 1.6 7.8 7.2 0.12 11.5 1.7 1.8 2 0 0 2 2 2 0 Mediator complex subunit 3 fungal Filament PF00038.21 OQS06171.1 - 3.3 7.2 56.4 0.79 9.2 43.5 2.7 1 1 1 2 2 2 0 Intermediate filament protein DUF244 PF03112.14 OQS06171.1 - 4.8 7.0 10.6 0.082 12.7 1.1 2.8 1 1 0 2 2 2 0 Uncharacterized protein family (ORF7) DUF KASH_CCD PF14662.6 OQS06171.1 - 6.8 6.5 66.2 0.009 15.9 37.0 2.9 1 1 2 3 3 3 0 Coiled-coil region of CCDC155 or KASH GIT_CC PF16559.5 OQS06171.1 - 10 6.1 22.7 0.3 11.0 1.5 5.8 4 2 0 5 5 5 0 GIT coiled-coil Rho guanine nucleotide exchange factor Dopey_N PF04118.14 OQS06173.1 - 0.0059 15.8 2.8 6.4 5.8 0.0 3.6 2 1 1 3 3 3 3 Dopey, N-terminal DUF3677 PF12432.8 OQS06173.1 - 0.0063 16.8 0.3 0.018 15.3 0.3 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF3677) HEAT_EZ PF13513.6 OQS06173.1 - 0.0079 16.7 0.3 5.2 7.7 0.0 2.8 2 0 0 2 2 2 2 HEAT-like repeat HEAT PF02985.22 OQS06173.1 - 0.026 14.8 0.2 4.7 7.7 0.0 3.7 3 0 0 3 3 3 0 HEAT repeat TLD PF07534.16 OQS06174.1 - 5.8e-33 114.1 0.1 8.1e-33 113.6 0.1 1.2 1 0 0 1 1 1 1 TLD LysM PF01476.20 OQS06174.1 - 7.7e-10 38.7 0.0 2.5e-09 37.1 0.0 1.9 2 0 0 2 2 2 1 LysM domain WD40 PF00400.32 OQS06175.1 - 2.2e-21 75.8 25.6 2.8e-08 34.3 0.5 10.8 11 0 0 11 11 11 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OQS06175.1 - 5.2e-21 74.7 9.0 0.00025 21.3 0.0 7.3 3 3 4 7 7 7 5 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 OQS06175.1 - 1.2e-05 24.8 0.5 0.095 12.0 0.0 2.8 2 0 0 2 2 2 2 WD40-like domain BBS2_Mid PF14783.6 OQS06175.1 - 0.00051 20.1 0.6 1.3 9.1 0.1 5.1 5 0 0 5 5 5 1 Ciliary BBSome complex subunit 2, middle region Clathrin PF00637.20 OQS06175.1 - 0.0046 16.8 0.3 0.26 11.2 0.1 2.6 2 0 0 2 2 2 1 Region in Clathrin and VPS IFRD PF05004.13 OQS06176.1 - 4.5e-63 213.2 2.3 4.5e-63 213.2 2.3 1.8 2 0 0 2 2 2 1 Interferon-related developmental regulator (IFRD) HEAT PF02985.22 OQS06176.1 - 0.00018 21.5 0.5 0.54 10.7 0.0 4.2 4 0 0 4 4 4 1 HEAT repeat HEAT_2 PF13646.6 OQS06176.1 - 0.0018 18.6 0.2 0.058 13.8 0.1 2.9 2 1 1 3 3 3 2 HEAT repeats Cnd3 PF12719.7 OQS06176.1 - 0.13 11.5 3.4 2.6 7.2 3.4 2.7 1 1 0 1 1 1 0 Nuclear condensing complex subunits, C-term domain Endonuclease_5 PF04493.14 OQS06177.1 - 8.4e-60 201.8 0.0 1.1e-59 201.5 0.0 1.1 1 0 0 1 1 1 1 Endonuclease V UvrC_HhH_N PF08459.11 OQS06177.1 - 0.05 13.5 0.0 7.3 6.5 0.0 2.3 2 0 0 2 2 2 0 UvrC Helix-hairpin-helix N-terminal DUF99 PF01949.16 OQS06177.1 - 0.09 12.2 0.0 0.25 10.8 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function DUF99 COPI_assoc PF08507.10 OQS06178.1 - 1.7e-06 28.1 8.4 2.6e-06 27.5 8.4 1.2 1 0 0 1 1 1 1 COPI associated protein DUF5429 PF17494.2 OQS06178.1 - 0.14 12.2 0.0 0.25 11.4 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5429) DUF5325 PF17259.2 OQS06178.1 - 0.16 11.8 7.6 0.38 10.6 4.7 2.6 2 1 0 2 2 2 0 Family of unknown function (DUF5325) YtpI PF14007.6 OQS06178.1 - 1.1 9.5 11.5 0.53 10.4 8.0 2.3 1 1 1 2 2 2 0 YtpI-like protein DUF373 PF04123.13 OQS06178.1 - 1.9 7.9 9.3 4.2 6.7 3.2 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF373) MORN PF02493.20 OQS06179.1 - 1.8e-94 304.3 143.6 3.2e-07 29.9 0.6 22.9 23 0 0 23 23 23 20 MORN repeat FYVE PF01363.21 OQS06179.1 - 8.2e-15 54.7 11.3 1.7e-14 53.7 11.3 1.6 1 0 0 1 1 1 1 FYVE zinc finger DUSP PF06337.12 OQS06179.1 - 8.2e-13 48.8 0.2 3.4e-12 46.8 0.0 2.1 2 0 0 2 2 2 1 DUSP domain FYVE_2 PF02318.16 OQS06179.1 - 0.00049 20.3 7.9 0.0016 18.7 7.9 1.8 1 0 0 1 1 1 1 FYVE-type zinc finger IQ PF00612.27 OQS06179.1 - 0.002 17.8 2.8 0.31 11.0 0.5 2.7 2 0 0 2 2 2 2 IQ calmodulin-binding motif OrsD PF12013.8 OQS06179.1 - 0.19 12.2 0.0 0.19 12.2 0.0 2.7 3 0 0 3 3 2 0 Orsellinic acid/F9775 biosynthesis cluster protein D DUF3920 PF13058.6 OQS06179.1 - 0.2 11.9 1.6 0.46 10.7 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3920) Rhodanese_C PF12368.8 OQS06179.1 - 0.95 9.9 6.0 2.3 8.6 6.0 1.7 1 0 0 1 1 1 0 Rhodanase C-terminal DUF296 PF03479.15 OQS06179.1 - 2.4 8.6 5.7 6.4 7.2 0.3 3.4 3 1 0 3 3 3 0 Plants and Prokaryotes Conserved (PCC) domain Siva PF05458.12 OQS06179.1 - 3 7.5 7.5 1.2 8.8 4.5 1.8 2 0 0 2 2 2 0 Cd27 binding protein (Siva) Prok-RING_2 PF14445.6 OQS06179.1 - 7.1 6.9 11.0 3.6 7.8 7.6 2.4 2 1 0 2 2 2 0 Prokaryotic RING finger family 2 Abhydrolase_3 PF07859.13 OQS06180.1 - 9.8e-39 133.4 0.1 1.3e-38 133.0 0.1 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 OQS06180.1 - 1.2e-25 90.2 0.1 8.2e-24 84.2 0.1 2.0 1 1 0 1 1 1 1 Steryl acetyl hydrolase Peptidase_S9 PF00326.21 OQS06180.1 - 0.01 15.3 0.0 0.017 14.6 0.0 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 OQS06180.1 - 0.023 13.9 0.0 0.3 10.3 0.0 2.2 1 1 1 2 2 2 0 Serine aminopeptidase, S33 PH PF00169.29 OQS06181.1 - 6e-26 91.0 1.4 3.4e-10 40.4 0.1 4.9 4 0 0 4 4 4 4 PH domain PH_11 PF15413.6 OQS06181.1 - 0.00017 22.0 10.9 0.29 11.6 1.3 4.5 4 1 0 4 4 4 2 Pleckstrin homology domain PH_8 PF15409.6 OQS06181.1 - 0.00022 21.5 6.4 0.033 14.5 0.3 3.7 3 0 0 3 3 3 2 Pleckstrin homology domain YkuI_C PF10388.9 OQS06181.1 - 0.0073 16.1 0.2 0.032 14.0 0.1 2.0 2 0 0 2 2 2 1 EAL-domain associated signalling protein domain SCIMP PF15050.6 OQS06181.1 - 0.25 11.8 0.0 0.25 11.8 0.0 2.1 3 0 0 3 3 3 0 SCIMP protein tRNA-synt_1d PF00750.19 OQS06182.1 - 7.7e-116 386.8 1.2 1.2e-115 386.2 0.4 1.6 2 0 0 2 2 2 1 tRNA synthetases class I (R) DALR_1 PF05746.15 OQS06182.1 - 3.8e-22 78.7 0.1 1e-21 77.3 0.1 1.8 1 0 0 1 1 1 1 DALR anticodon binding domain Arg_tRNA_synt_N PF03485.16 OQS06182.1 - 3.4e-19 69.2 0.1 9e-19 67.9 0.1 1.8 1 0 0 1 1 1 1 Arginyl tRNA synthetase N terminal domain GST_C PF00043.25 OQS06182.1 - 0.0017 18.6 0.0 0.0038 17.4 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain tRNA-synt_1e PF01406.19 OQS06182.1 - 0.0017 17.7 0.2 0.0057 16.0 0.2 1.9 1 1 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain GST_C_3 PF14497.6 OQS06182.1 - 0.0024 18.0 0.0 0.022 15.0 0.0 2.4 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain tRNA-synt_1g PF09334.11 OQS06182.1 - 0.0031 16.3 0.0 0.0046 15.8 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 OQS06182.1 - 0.0084 14.4 0.0 0.017 13.4 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) GST_C_2 PF13410.6 OQS06182.1 - 0.08 13.0 0.0 0.2 11.7 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Pex2_Pex12 PF04757.14 OQS06183.1 - 7.6e-25 87.8 1.9 1e-24 87.4 1.9 1.1 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4 PF00097.25 OQS06183.1 - 1.2e-05 25.0 8.3 2e-05 24.3 8.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OQS06183.1 - 3.4e-05 23.7 7.1 5.7e-05 23.0 7.1 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 OQS06183.1 - 5.8e-05 22.9 4.7 8.6e-05 22.3 4.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 OQS06183.1 - 0.0029 17.4 7.5 0.0097 15.7 8.0 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 OQS06183.1 - 0.0034 17.2 4.1 0.0057 16.5 4.1 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 OQS06183.1 - 0.0044 17.3 6.0 0.0072 16.6 6.0 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 OQS06183.1 - 0.13 12.3 3.8 0.17 12.0 2.8 1.7 1 1 0 1 1 1 0 RING-type zinc-finger zf-rbx1 PF12678.7 OQS06183.1 - 0.35 11.2 3.6 0.62 10.4 3.6 1.4 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-RING_4 PF14570.6 OQS06183.1 - 0.72 9.7 5.6 1.3 8.8 5.6 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.6 OQS06183.1 - 0.94 9.7 8.5 2.3 8.5 8.6 1.7 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING Cupin_8 PF13621.6 OQS06184.1 - 6.1e-55 186.7 0.0 7.8e-55 186.3 0.0 1.1 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.12 OQS06184.1 - 0.00016 21.3 0.0 0.027 13.9 0.0 2.5 2 0 0 2 2 2 2 Cupin superfamily protein DENN PF02141.21 OQS06186.1 - 1.1e-42 146.1 4.0 6.3e-42 143.6 4.0 2.2 1 1 0 1 1 1 1 DENN (AEX-3) domain uDENN PF03456.18 OQS06186.1 - 2e-13 50.9 0.1 1.7e-12 47.9 0.0 2.7 2 0 0 2 2 2 1 uDENN domain dDENN PF03455.19 OQS06186.1 - 0.00028 20.8 5.5 0.002 18.1 5.3 2.3 2 0 0 2 2 2 1 dDENN domain PDZ_6 PF17820.1 OQS06186.1 - 0.00073 19.3 0.0 0.0014 18.4 0.0 1.4 1 0 0 1 1 1 1 PDZ domain DUF512 PF04459.12 OQS06186.1 - 0.034 13.4 0.0 0.072 12.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF512) Pkinase PF00069.25 OQS06187.1 - 2.5e-76 256.5 0.0 3e-76 256.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQS06187.1 - 3.6e-38 131.3 0.5 9.2e-38 130.0 0.5 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 OQS06187.1 - 0.021 14.8 0.0 0.069 13.1 0.0 1.6 1 1 1 2 2 2 0 Phosphotransferase enzyme family Bact_lectin PF18483.1 OQS06188.1 - 2.1e-17 63.8 3.5 5.7e-17 62.4 0.1 2.5 2 1 0 2 2 2 1 Bacterial lectin Lectin_legB PF00139.19 OQS06188.1 - 1.9e-12 47.3 0.1 1.6e-11 44.2 0.1 2.1 1 1 0 1 1 1 1 Legume lectin domain fn3 PF00041.21 OQS06188.1 - 3.9e-08 33.5 1.4 1e-07 32.2 1.4 1.7 1 0 0 1 1 1 1 Fibronectin type III domain TIG PF01833.24 OQS06188.1 - 5.5e-06 26.4 0.1 5.5e-06 26.4 0.1 2.6 3 0 0 3 3 3 1 IPT/TIG domain CCDC53 PF10152.9 OQS06189.1 - 1.1 9.6 28.8 0.76 10.2 14.6 3.4 2 1 0 2 2 2 0 Subunit CCDC53 of WASH complex PH_13 PF16652.5 OQS06189.1 - 8.6 6.1 7.7 0.18 11.6 0.7 1.8 2 0 0 2 2 2 0 Pleckstrin homology domain LicD PF04991.13 OQS06190.1 - 9.5e-22 78.3 0.2 2.9e-21 76.7 0.2 1.7 1 1 0 1 1 1 1 LicD family PP2C PF00481.21 OQS06191.1 - 4e-37 128.3 0.0 1.9e-36 126.0 0.0 1.9 1 1 0 1 1 1 1 Protein phosphatase 2C Pkinase PF00069.25 OQS06191.1 - 1.2e-34 119.8 0.0 2.6e-34 118.8 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQS06191.1 - 1.9e-11 43.7 0.0 3.1e-11 43.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OQS06191.1 - 1.4e-05 24.5 0.0 2.7e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 Kinase-like PP2C_2 PF13672.6 OQS06191.1 - 0.00019 21.1 0.0 0.00071 19.3 0.0 1.9 1 1 0 1 1 1 1 Protein phosphatase 2C zf-C2HC_2 PF13913.6 OQS06191.1 - 0.0051 16.7 1.4 0.014 15.3 0.6 2.1 2 0 0 2 2 2 1 zinc-finger of a C2HC-type APH PF01636.23 OQS06191.1 - 0.0088 16.0 0.0 0.029 14.3 0.0 1.9 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 OQS06191.1 - 0.025 13.9 0.1 0.05 13.0 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 OQS06191.1 - 0.063 12.1 0.0 0.1 11.4 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase FTA2 PF13095.6 OQS06191.1 - 0.085 12.5 0.5 0.48 10.0 0.0 2.1 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 DUF1899 PF08953.11 OQS06192.1 - 8.9e-25 86.4 0.2 1.6e-24 85.5 0.2 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1899) WD40_4 PF16300.5 OQS06192.1 - 2e-18 66.0 0.0 4.1e-18 65.0 0.0 1.6 1 0 0 1 1 1 1 Type of WD40 repeat WD40 PF00400.32 OQS06192.1 - 6.6e-15 55.2 0.6 0.0028 18.5 0.1 5.2 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OQS06192.1 - 2.4e-07 30.9 0.2 8.5e-05 22.8 0.1 3.0 1 1 1 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 OQS06192.1 - 0.0017 17.4 0.0 1.3 7.9 0.0 3.2 1 1 1 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 OQS06192.1 - 0.002 16.9 0.1 0.022 13.4 0.1 2.2 1 1 0 1 1 1 1 Nucleoporin Nup120/160 DNA_Packaging_2 PF11123.8 OQS06192.1 - 0.022 15.0 0.0 0.42 10.9 0.0 2.5 2 0 0 2 2 2 0 DNA packaging protein ABC_tran_CTD PF16326.5 OQS06192.1 - 0.098 12.9 1.5 0.18 12.1 0.5 1.9 2 0 0 2 2 2 0 ABC transporter C-terminal domain DUF4140 PF13600.6 OQS06192.1 - 0.19 12.2 0.8 0.48 10.9 0.8 1.6 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) Protocadherin PF08374.11 OQS06193.1 - 0.051 13.5 0.3 0.88 9.5 0.0 1.9 1 1 1 2 2 2 0 Protocadherin FYVE PF01363.21 OQS06194.1 - 3.6e-09 36.6 5.9 9.6e-09 35.3 5.9 1.7 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.16 OQS06194.1 - 0.006 16.8 3.3 0.018 15.2 3.3 1.8 1 0 0 1 1 1 1 FYVE-type zinc finger SBP PF03110.14 OQS06194.1 - 0.58 10.5 5.6 0.53 10.6 3.7 2.0 2 0 0 2 2 2 0 SBP domain C1_2 PF03107.16 OQS06194.1 - 5.9 7.3 7.8 1.3 9.4 3.7 2.1 2 0 0 2 2 2 0 C1 domain TFIIF_alpha PF05793.12 OQS06195.1 - 0.00014 20.6 7.0 0.00018 20.3 7.0 1.0 1 0 0 1 1 1 1 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Senescence_reg PF04520.13 OQS06195.1 - 1.3 9.9 17.9 8.6 7.2 17.9 2.3 1 1 0 1 1 1 0 Senescence regulator FAM60A PF15396.6 OQS06195.1 - 8.1 6.4 8.2 6.4 6.7 6.8 1.5 1 1 0 1 1 1 0 Protein Family FAM60A DUF2512 PF10710.9 OQS06196.1 - 1.5 8.5 10.9 0.039 13.6 2.3 2.0 1 1 0 2 2 2 0 Protein of unknown function (DUF2512) DUF2723 PF11028.8 OQS06196.1 - 8.4 6.3 12.4 1.5 8.7 4.9 2.3 1 1 2 3 3 3 0 Protein of unknown function (DUF2723) Piwi PF02171.17 OQS06197.1 - 3e-87 292.7 0.0 3.6e-87 292.4 0.0 1.0 1 0 0 1 1 1 1 Piwi domain Gly-rich_Ago1 PF12764.7 OQS06197.1 - 0.14 12.9 0.1 0.47 11.2 0.0 1.9 2 0 0 2 2 2 0 Glycine-rich region of argonaut DUF2009 PF09418.10 OQS06198.1 - 4.3e-190 632.6 0.0 4.9e-190 632.4 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2009) zf-B_box PF00643.24 OQS06198.1 - 8.6e-06 25.8 2.3 8.6e-06 25.8 2.3 2.0 2 0 0 2 2 2 1 B-box zinc finger zf-C3HC4_3 PF13920.6 OQS06198.1 - 0.0031 17.3 3.9 0.0069 16.2 3.9 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) CEBP_ZZ PF16366.5 OQS06198.1 - 0.0035 17.5 2.3 0.0035 17.5 2.3 2.0 2 0 0 2 2 2 1 Cytoplasmic polyadenylation element-binding protein ZZ domain Prok-RING_4 PF14447.6 OQS06198.1 - 4.7 7.1 7.1 2.5 8.0 4.0 2.0 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 SMC_ScpB PF04079.16 OQS06199.1 - 0.22 11.1 2.6 2 8.0 0.1 2.2 1 1 1 2 2 2 0 Segregation and condensation complex subunit ScpB PTCB-BRCT PF12738.7 OQS06200.1 - 1.4e-40 137.1 7.4 4.1e-15 55.5 0.2 4.9 5 0 0 5 5 5 4 twin BRCT domain BRCT PF00533.26 OQS06200.1 - 2.4e-33 114.3 0.0 3.7e-09 36.8 0.0 5.3 5 0 0 5 5 5 4 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 OQS06200.1 - 3.4e-15 56.2 0.0 0.0071 16.7 0.0 4.5 4 0 0 4 4 4 4 BRCT domain, a BRCA1 C-terminus domain LIG3_BRCT PF16759.5 OQS06200.1 - 4.6e-09 36.4 0.2 0.17 12.2 0.0 5.2 5 0 0 5 5 5 2 DNA ligase 3 BRCT domain BRCT_3 PF18428.1 OQS06200.1 - 2.7e-08 33.8 1.7 0.28 11.3 0.2 4.7 4 1 0 4 4 4 3 BRCA1 C Terminus (BRCT) domain RTT107_BRCT_5 PF16770.5 OQS06200.1 - 0.00073 19.4 0.0 7.2 6.6 0.0 3.8 4 0 0 4 4 4 2 Regulator of Ty1 transposition protein 107 BRCT domain Stm1_N PF09598.10 OQS06200.1 - 3.3 8.6 9.7 0.37 11.7 3.7 2.2 2 0 0 2 2 2 0 Stm1 GAF PF01590.26 OQS06201.1 - 8.5e-24 84.7 0.0 4.7e-14 53.1 0.0 4.4 4 0 0 4 4 4 3 GAF domain GAF_3 PF13492.6 OQS06201.1 - 1e-11 45.3 0.0 0.00012 22.5 0.0 4.9 4 1 0 4 4 4 3 GAF domain SpoVT_C PF15714.5 OQS06201.1 - 0.0032 17.5 0.0 0.022 14.8 0.0 2.5 2 0 0 2 2 2 1 Stage V sporulation protein T C-terminal, transcription factor EF-hand_6 PF13405.6 OQS06201.1 - 0.0055 16.5 0.0 0.019 14.9 0.0 1.9 1 0 0 1 1 1 1 EF-hand domain EF-hand_1 PF00036.32 OQS06201.1 - 0.037 13.6 0.0 0.12 12.0 0.0 1.9 1 0 0 1 1 1 0 EF hand Tropomyosin_1 PF12718.7 OQS06201.1 - 0.82 9.8 16.1 0.14 12.3 5.1 2.5 2 0 0 2 2 2 0 Tropomyosin like Cnn_1N PF07989.11 OQS06201.1 - 3.2 8.0 22.1 4.1 7.6 5.0 3.5 3 0 0 3 3 3 0 Centrosomin N-terminal motif 1 DUF4140 PF13600.6 OQS06201.1 - 4.5 7.8 8.1 25 5.4 0.3 2.5 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) Peptidase_M17 PF00883.21 OQS06202.1 - 1.1e-96 323.8 0.6 1.5e-96 323.3 0.6 1.2 1 0 0 1 1 1 1 Cytosol aminopeptidase family, catalytic domain Pdase_M17_N2 PF18295.1 OQS06202.1 - 4e-26 91.7 0.0 1.1e-25 90.2 0.0 1.7 1 0 0 1 1 1 1 M17 aminopeptidase N-terminal domain 2 DUF3037 PF11236.8 OQS06202.1 - 0.023 15.1 0.0 0.055 13.9 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3037) FYVE PF01363.21 OQS06203.1 - 1.9e-11 43.9 11.7 1.9e-11 43.9 11.7 3.6 2 1 1 3 3 3 2 FYVE zinc finger zf-RING_2 PF13639.6 OQS06203.1 - 1e-09 38.5 33.8 1.5e-09 38.0 6.5 5.0 5 0 0 5 5 5 2 Ring finger domain zf-RING_11 PF17123.5 OQS06203.1 - 3.7e-09 36.2 4.6 3.7e-09 36.2 4.6 3.3 3 0 0 3 3 3 1 RING-like zinc finger zf-RING_UBOX PF13445.6 OQS06203.1 - 7.8e-07 29.0 2.2 7.8e-07 29.0 2.2 4.3 4 1 1 5 5 5 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 OQS06203.1 - 9.8e-07 28.5 5.7 9.8e-07 28.5 5.7 5.2 4 1 1 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 OQS06203.1 - 1.4e-06 28.1 6.2 1.4e-06 28.1 6.2 4.9 4 1 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OQS06203.1 - 1.7e-06 27.9 5.3 1.7e-06 27.9 5.3 4.4 3 2 0 3 3 3 1 zinc-RING finger domain zf-RING_4 PF14570.6 OQS06203.1 - 0.00015 21.4 1.6 0.00015 21.4 1.6 4.4 5 0 0 5 5 5 1 RING/Ubox like zinc-binding domain FYVE_2 PF02318.16 OQS06203.1 - 0.0051 17.0 8.0 0.0051 17.0 8.0 3.2 3 1 1 4 4 3 1 FYVE-type zinc finger zf-C3HC4_4 PF15227.6 OQS06203.1 - 0.012 15.8 4.9 0.012 15.8 4.9 4.7 6 0 0 6 6 4 0 zinc finger of C3HC4-type, RING zf-RING-like PF08746.11 OQS06203.1 - 0.013 15.8 5.6 0.013 15.8 5.6 3.7 4 1 0 4 4 2 0 RING-like domain PHD PF00628.29 OQS06203.1 - 0.014 15.3 5.5 0.014 15.3 5.5 4.6 4 1 1 5 5 5 0 PHD-finger Nudix_N_2 PF14803.6 OQS06203.1 - 0.38 10.7 0.1 0.38 10.7 0.1 5.8 5 1 1 6 6 6 0 Nudix N-terminal DZR PF12773.7 OQS06203.1 - 0.78 9.8 37.1 1.3 9.1 6.9 5.1 2 2 3 5 5 5 0 Double zinc ribbon zf-dskA_traR PF01258.17 OQS06203.1 - 0.94 9.5 12.1 1.2 9.2 0.0 4.5 3 1 1 4 4 4 0 Prokaryotic dksA/traR C4-type zinc finger zf-C2H2_6 PF13912.6 OQS06203.1 - 1.2 9.3 12.8 9.1 6.4 0.3 4.9 4 0 0 4 4 4 0 C2H2-type zinc finger zf-RING_10 PF16685.5 OQS06203.1 - 4.6 7.4 21.8 2.4 8.4 5.3 3.5 2 1 1 3 3 3 0 zinc RING finger of MSL2 Zn-ribbon_8 PF09723.10 OQS06203.1 - 5.8 7.1 32.6 0.83 9.8 0.8 5.6 4 2 2 6 6 6 0 Zinc ribbon domain BLOC1_2 PF10046.9 OQS06204.1 - 0.006 16.8 2.9 0.0065 16.7 1.1 1.9 1 1 1 2 2 2 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF1722 PF08349.11 OQS06204.1 - 0.087 13.1 1.8 0.15 12.4 0.7 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1722) HU-CCDC81_bac_2 PF18175.1 OQS06204.1 - 0.14 12.0 4.5 2.1 8.3 0.3 2.8 1 1 2 3 3 3 0 CCDC81-like prokaryotic HU domain 2 DUF948 PF06103.11 OQS06204.1 - 0.95 9.8 5.8 0.48 10.7 0.7 2.4 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) Peptidase_S15 PF02129.18 OQS06205.1 - 1.3e-35 123.3 0.0 2.3e-35 122.5 0.0 1.4 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) PepX_C PF08530.10 OQS06205.1 - 1e-15 58.3 0.0 1.8e-15 57.5 0.0 1.4 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain FYVE PF01363.21 OQS06205.1 - 9.1e-15 54.6 12.1 1.7e-14 53.7 12.1 1.5 1 0 0 1 1 1 1 FYVE zinc finger GAF_2 PF13185.6 OQS06205.1 - 1.3e-05 25.5 0.0 2.9e-05 24.4 0.0 1.6 1 0 0 1 1 1 1 GAF domain Hydrolase_4 PF12146.8 OQS06205.1 - 0.0053 16.1 0.0 0.013 14.7 0.0 1.6 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 OQS06205.1 - 0.076 12.6 0.0 1.5 8.4 0.0 2.4 2 0 0 2 2 2 0 alpha/beta hydrolase fold CBM9_1 PF06452.11 OQS06206.1 - 5.3e-12 46.0 0.4 1.2e-11 44.8 0.4 1.8 1 1 0 1 1 1 1 Carbohydrate family 9 binding domain-like CBM9_2 PF16011.5 OQS06206.1 - 4e-08 33.2 0.0 6.9e-08 32.4 0.0 1.3 1 0 0 1 1 1 1 Carbohydrate-binding family 9 Integrase_DNA PF02920.15 OQS06206.1 - 0.13 11.9 0.6 0.62 9.8 0.0 2.3 2 0 0 2 2 2 0 DNA binding domain of tn916 integrase Cytochrom_B561 PF03188.16 OQS06208.1 - 2.5e-19 69.8 1.2 2.5e-19 69.8 1.2 2.1 3 1 0 3 3 3 1 Eukaryotic cytochrome b561 YwiC PF14256.6 OQS06208.1 - 0.00021 21.6 2.3 0.099 13.0 0.1 2.5 1 1 1 2 2 2 2 YwiC-like protein DUF4079 PF13301.6 OQS06208.1 - 0.0017 18.5 1.9 0.0054 16.9 0.4 2.1 1 1 1 2 2 2 1 Protein of unknown function (DUF4079) DUF3810 PF12725.7 OQS06208.1 - 0.011 15.2 0.3 0.021 14.2 0.2 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3810) DUF3325 PF11804.8 OQS06208.1 - 0.17 12.0 8.6 0.17 12.0 4.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3325) PMT_4TMC PF16192.5 OQS06208.1 - 0.6 9.7 4.9 0.3 10.7 1.4 2.1 1 1 1 2 2 2 0 C-terminal four TMM region of protein-O-mannosyltransferase SdpI PF13630.6 OQS06208.1 - 0.73 10.0 10.4 0.81 9.9 0.6 3.5 3 1 0 3 3 3 0 SdpI/YhfL protein family HIG_1_N PF04588.13 OQS06208.1 - 0.84 9.9 5.1 0.69 10.2 0.3 3.1 3 1 0 3 3 3 0 Hypoxia induced protein conserved region Aminotran_4 PF01063.19 OQS06209.1 - 8.4e-17 61.8 0.1 1.1e-15 58.1 0.1 2.0 1 1 0 1 1 1 1 Amino-transferase class IV EF-hand_7 PF13499.6 OQS06210.1 - 5e-19 68.5 0.7 5.5e-08 33.2 0.0 2.8 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 OQS06210.1 - 1.3e-18 65.1 9.1 3.8e-06 26.1 0.1 5.0 5 0 0 5 5 5 4 EF hand EF-hand_6 PF13405.6 OQS06210.1 - 6.8e-18 63.0 4.3 9.3e-05 22.1 0.1 4.9 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 OQS06210.1 - 3.5e-14 52.4 0.1 7.7e-07 28.9 0.1 3.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 OQS06210.1 - 5.4e-14 50.9 8.2 0.00033 20.0 0.1 4.7 4 0 0 4 4 4 4 EF hand LRR_6 PF13516.6 OQS06210.1 - 1.6e-13 49.5 20.6 0.052 13.6 0.0 7.6 8 0 0 8 8 7 5 Leucine Rich repeat DUF4476 PF14771.6 OQS06210.1 - 7e-09 35.9 0.2 7.8e-06 26.1 0.0 3.6 3 0 0 3 3 3 1 Domain of unknown function (DUF4476) EF-hand_9 PF14658.6 OQS06210.1 - 5.4e-07 29.9 0.3 0.0016 18.7 0.1 2.6 2 0 0 2 2 2 2 EF-hand domain LRR_8 PF13855.6 OQS06210.1 - 0.00032 20.4 8.1 0.071 12.9 0.0 4.9 4 1 1 5 5 5 1 Leucine rich repeat LRR_4 PF12799.7 OQS06210.1 - 0.00057 20.2 6.7 0.32 11.5 0.0 4.3 3 1 1 4 4 4 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 OQS06210.1 - 0.0031 17.8 5.1 11 7.1 0.0 5.1 5 0 0 5 5 4 1 Leucine Rich Repeat Trp_repressor PF01371.19 OQS06210.1 - 0.051 13.7 1.0 0.77 9.9 0.0 3.2 3 0 0 3 3 3 0 Trp repressor protein Cas_Cas7 PF05107.12 OQS06211.1 - 0.07 12.7 0.0 0.079 12.5 0.0 1.1 1 0 0 1 1 1 0 CRISPR-associated protein Cas7 RRM_1 PF00076.22 OQS06212.1 - 1.7e-55 184.8 0.0 2e-20 72.4 0.0 3.5 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 OQS06212.1 - 2.6e-08 33.9 0.0 0.62 10.2 0.0 4.0 3 3 0 3 3 3 3 RNA recognition motif RNA_bind PF08675.11 OQS06212.1 - 0.0027 17.7 0.0 8 6.6 0.0 3.6 3 0 0 3 3 3 1 RNA binding domain PHM7_cyt PF14703.6 OQS06212.1 - 0.0027 18.0 0.1 2.2 8.5 0.0 3.5 3 1 0 3 3 3 1 Cytosolic domain of 10TM putative phosphate transporter dTDP_sugar_isom PF00908.17 OQS06212.1 - 0.098 12.3 0.0 0.86 9.3 0.0 2.3 3 0 0 3 3 3 0 dTDP-4-dehydrorhamnose 3,5-epimerase HECT PF00632.25 OQS06213.1 - 5.1e-72 242.9 0.0 7.2e-72 242.5 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) zf-RanBP PF00641.18 OQS06213.1 - 0.004 16.5 4.0 0.0079 15.5 4.0 1.5 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others Consortin_C PF15281.6 OQS06213.1 - 0.055 13.5 0.3 0.12 12.4 0.3 1.5 1 0 0 1 1 1 0 Consortin C-terminus Vps36-NZF-N PF16988.5 OQS06213.1 - 0.066 12.6 6.2 0.29 10.5 6.2 2.0 1 1 0 1 1 1 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain Flu_NS1 PF00600.19 OQS06213.1 - 0.18 11.3 0.0 0.31 10.6 0.0 1.3 1 0 0 1 1 1 0 Influenza non-structural protein (NS1) Zip PF02535.22 OQS06214.1 - 3e-49 168.1 16.7 9.1e-49 166.5 16.7 1.6 1 1 0 1 1 1 1 ZIP Zinc transporter DUF2070 PF09843.9 OQS06214.1 - 0.31 9.3 5.1 0.48 8.6 5.1 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Thioredoxin_6 PF13848.6 OQS06215.1 - 4.9e-06 26.6 0.0 9.8e-06 25.6 0.0 1.7 1 1 0 1 1 1 1 Thioredoxin-like domain Dmd PF17587.2 OQS06215.1 - 0.028 14.8 0.2 1.2 9.5 0.0 2.5 3 0 0 3 3 3 0 Discriminator of mRNA degradation MIT PF04212.18 OQS06216.1 - 0.081 13.0 0.9 10 6.3 0.0 2.7 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain Peptidase_M17 PF00883.21 OQS06217.1 - 2.5e-33 115.7 0.0 3.7e-33 115.1 0.0 1.2 1 0 0 1 1 1 1 Cytosol aminopeptidase family, catalytic domain Pdase_M17_N2 PF18295.1 OQS06217.1 - 8e-23 81.0 0.1 1.6e-22 80.0 0.0 1.6 2 0 0 2 2 2 1 M17 aminopeptidase N-terminal domain 2 ubiquitin PF00240.23 OQS06218.1 - 6.3e-18 64.3 0.0 1.2e-17 63.4 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family LRR_6 PF13516.6 OQS06218.1 - 5.7e-13 47.8 4.6 0.0032 17.4 0.1 4.7 4 0 0 4 4 4 3 Leucine Rich repeat Rad60-SLD PF11976.8 OQS06218.1 - 9.4e-06 25.4 0.0 2e-05 24.3 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like LRR_4 PF12799.7 OQS06218.1 - 1.3e-05 25.5 0.0 0.99 9.9 0.0 4.3 3 1 1 4 4 4 2 Leucine Rich repeats (2 copies) Tudor-knot PF11717.8 OQS06218.1 - 0.00033 20.5 1.0 0.0011 18.8 1.0 1.9 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Ubiquitin_2 PF14560.6 OQS06218.1 - 0.0045 17.4 0.0 0.012 16.0 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin-like domain DUF2407 PF10302.9 OQS06218.1 - 0.023 15.2 0.0 0.084 13.4 0.0 1.9 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain LRR_8 PF13855.6 OQS06218.1 - 0.11 12.3 0.1 2.3 8.1 0.1 3.1 1 1 0 1 1 1 0 Leucine rich repeat Ubiquitin_4 PF18036.1 OQS06218.1 - 0.12 12.4 0.0 2.8 8.0 0.0 2.4 1 1 0 1 1 1 0 Ubiquitin-like domain zf-CHCC PF10276.9 OQS06219.1 - 2.9e-16 59.2 0.6 3.9e-16 58.8 0.6 1.2 1 0 0 1 1 1 1 Zinc-finger domain zf_C2H2_6 PF18450.1 OQS06219.1 - 0.0052 16.5 0.1 0.011 15.4 0.1 1.5 1 0 0 1 1 1 1 Zinc Finger domain GATA PF00320.27 OQS06219.1 - 0.025 14.2 0.1 0.037 13.6 0.1 1.3 1 0 0 1 1 1 0 GATA zinc finger PhyH PF05721.13 OQS06220.1 - 8.5e-08 32.7 1.7 1.7e-07 31.7 1.7 1.5 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Het-C PF07217.11 OQS06221.1 - 0.0046 15.6 0.7 0.011 14.3 0.2 1.7 2 0 0 2 2 2 1 Heterokaryon incompatibility protein Het-C Mistic PF11458.8 OQS06221.1 - 0.063 13.3 0.8 0.14 12.1 0.1 1.9 2 0 0 2 2 2 0 Membrane-integrating protein Mistic BRCA-2_OB1 PF09103.10 OQS06221.1 - 0.14 12.1 0.0 0.28 11.2 0.0 1.4 1 0 0 1 1 1 0 BRCA2, oligonucleotide/oligosaccharide-binding, domain 1 FYVE PF01363.21 OQS06222.1 - 4.5e-15 55.5 11.4 1.1e-14 54.3 11.4 1.7 1 0 0 1 1 1 1 FYVE zinc finger FIST PF08495.10 OQS06222.1 - 1.5e-12 47.8 0.0 4e-12 46.5 0.0 1.7 2 0 0 2 2 2 1 FIST N domain FYVE_2 PF02318.16 OQS06222.1 - 0.0011 19.2 3.1 0.003 17.7 3.1 1.7 1 0 0 1 1 1 1 FYVE-type zinc finger IBR PF01485.21 OQS06222.1 - 6.1 7.2 9.8 0.48 10.7 4.5 1.9 2 0 0 2 2 2 0 IBR domain, a half RING-finger domain zf-B_box PF00643.24 OQS06222.1 - 7.8 6.8 7.8 4 7.7 4.8 2.1 2 0 0 2 2 2 0 B-box zinc finger TauE PF01925.19 OQS06223.1 - 0.0004 20.1 11.4 0.00082 19.1 11.4 1.6 1 1 0 1 1 1 1 Sulfite exporter TauE/SafE WD40 PF00400.32 OQS06224.1 - 6.2e-35 118.6 27.7 0.00015 22.4 0.6 10.7 11 0 0 11 11 11 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OQS06224.1 - 1.9e-14 53.7 9.0 0.49 10.7 0.2 7.6 4 3 4 8 8 8 7 Anaphase-promoting complex subunit 4 WD40 domain PDEase_I PF00233.19 OQS06225.1 - 5.7e-70 235.7 2.6 9.1e-70 235.1 2.6 1.3 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase FAM194 PF14977.6 OQS06226.1 - 7.4e-25 87.5 0.0 1.3e-24 86.7 0.0 1.3 1 0 0 1 1 1 1 FAM194 protein CUTL PF16557.5 OQS06226.1 - 0.095 12.9 0.1 0.29 11.3 0.1 1.8 1 0 0 1 1 1 0 CUT1-like DNA-binding domain of SATB Zip PF02535.22 OQS06226.1 - 6.9 5.8 8.1 11 5.1 8.1 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter TauE PF01925.19 OQS06227.1 - 1.4e-24 87.1 25.5 8.7e-13 48.4 2.5 2.4 2 0 0 2 2 2 2 Sulfite exporter TauE/SafE Tad PF13400.6 OQS06227.1 - 0.61 10.4 0.0 0.61 10.4 0.0 4.0 5 0 0 5 5 5 0 Putative Flp pilus-assembly TadE/G-like DUF2070 PF09843.9 OQS06227.1 - 2.9 6.0 7.8 1.1 7.5 0.3 2.2 2 0 0 2 2 2 0 Predicted membrane protein (DUF2070) Glyco_hydro_18 PF00704.28 OQS06228.1 - 6.1e-17 62.3 0.0 3.1e-16 60.0 0.0 1.7 1 1 0 2 2 2 1 Glycosyl hydrolases family 18 GHL10 PF02638.15 OQS06228.1 - 0.022 13.8 0.1 0.033 13.3 0.1 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase-like 10 QRPTase_C PF01729.19 OQS06229.1 - 1.2e-57 194.4 0.1 1.6e-57 194.0 0.1 1.1 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain QRPTase_N PF02749.16 OQS06229.1 - 2.6e-17 62.6 0.1 8.2e-17 61.0 0.0 1.9 2 0 0 2 2 2 1 Quinolinate phosphoribosyl transferase, N-terminal domain SURNod19 PF07712.12 OQS06230.1 - 2.1e-32 112.3 2.9 5.6e-31 107.6 2.9 2.3 1 1 0 1 1 1 1 Stress up-regulated Nod 19 TFIIS_C PF01096.18 OQS06232.1 - 3.3e-18 65.3 13.0 3.3e-18 65.2 2.0 3.0 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.16 OQS06232.1 - 4.5e-05 23.2 13.3 0.011 15.6 2.3 3.1 2 1 0 2 2 2 2 RNA polymerases M/15 Kd subunit DZR PF12773.7 OQS06232.1 - 6.9e-05 22.8 13.2 0.001 19.0 3.0 2.7 2 1 0 2 2 2 2 Double zinc ribbon TF_Zn_Ribbon PF08271.12 OQS06232.1 - 0.00013 21.4 15.2 0.0027 17.2 4.0 3.3 2 1 1 3 3 3 1 TFIIB zinc-binding zinc_ribbon_2 PF13240.6 OQS06232.1 - 0.00023 20.8 18.1 0.07 12.9 5.0 4.1 3 1 0 3 3 3 2 zinc-ribbon domain C1_1 PF00130.22 OQS06232.1 - 0.0012 18.7 6.2 0.0019 18.0 0.8 2.4 2 1 0 2 2 2 1 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-ribbon_3 PF13248.6 OQS06232.1 - 0.0013 18.1 19.5 0.14 11.6 5.4 4.2 3 1 1 4 4 4 3 zinc-ribbon domain Lar_restr_allev PF14354.6 OQS06232.1 - 0.0018 18.6 10.7 0.023 15.0 1.5 2.4 2 0 0 2 2 2 2 Restriction alleviation protein Lar Zn_Tnp_IS1595 PF12760.7 OQS06232.1 - 0.002 18.1 15.8 0.0041 17.1 1.2 3.2 2 1 1 3 3 3 1 Transposase zinc-ribbon domain zf-Mss51 PF13824.6 OQS06232.1 - 0.0099 16.0 16.3 1.8 8.7 3.6 3.3 1 1 1 3 3 3 2 Zinc-finger of mitochondrial splicing suppressor 51 Auto_anti-p27 PF06677.12 OQS06232.1 - 0.017 15.3 13.8 0.061 13.5 1.3 3.0 2 1 0 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) eIF-5_eIF-2B PF01873.17 OQS06232.1 - 0.034 14.0 0.5 0.034 14.0 0.5 2.1 2 0 0 2 2 2 0 Domain found in IF2B/IF5 zf-C2H2_3 PF13878.6 OQS06232.1 - 0.037 13.8 12.9 0.81 9.6 0.2 4.7 4 1 1 5 5 5 0 zinc-finger of acetyl-transferase ESCO Nudix_N_2 PF14803.6 OQS06232.1 - 0.041 13.8 16.4 7.6 6.6 1.8 4.3 2 2 1 3 3 3 0 Nudix N-terminal zf-TFIIB PF13453.6 OQS06232.1 - 0.064 12.6 1.3 0.064 12.6 1.3 2.5 2 1 0 2 2 2 0 Transcription factor zinc-finger PhnA_Zn_Ribbon PF08274.12 OQS06232.1 - 0.064 13.2 2.1 0.064 13.2 2.1 3.2 3 0 0 3 3 3 0 PhnA Zinc-Ribbon UPF0547 PF10571.9 OQS06232.1 - 0.07 13.2 18.3 0.52 10.4 0.5 4.3 4 0 0 4 4 4 0 Uncharacterised protein family UPF0547 Baculo_LEF5_C PF11792.8 OQS06232.1 - 0.073 12.8 0.0 0.073 12.8 0.0 2.9 4 0 0 4 4 3 0 Baculoviridae late expression factor 5 C-terminal domain tRNA-synt_1f PF01921.18 OQS06232.1 - 0.079 11.9 0.3 0.17 10.8 0.2 1.6 2 0 0 2 2 2 0 tRNA synthetases class I (K) HicB-like_2 PF15970.5 OQS06232.1 - 0.083 13.1 0.0 0.16 12.1 0.0 1.5 2 0 0 2 2 1 0 HicB_like antitoxin of bacterial toxin-antitoxin system FYVE_2 PF02318.16 OQS06232.1 - 0.093 12.9 3.7 4.4 7.5 0.8 2.1 1 1 1 2 2 2 0 FYVE-type zinc finger OrfB_Zn_ribbon PF07282.11 OQS06232.1 - 0.096 12.6 11.9 0.14 12.1 2.2 2.8 2 2 0 2 2 2 0 Putative transposase DNA-binding domain HypA PF01155.19 OQS06232.1 - 0.13 12.3 10.1 6.2 6.9 1.4 3.1 1 1 2 3 3 3 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zinc_ribbon_4 PF13717.6 OQS06232.1 - 0.16 11.9 12.1 6.2 6.8 0.3 4.1 3 1 0 3 3 3 0 zinc-ribbon domain Zn-ribbon_8 PF09723.10 OQS06232.1 - 0.19 11.8 21.7 1.4 9.1 1.3 4.3 3 1 2 5 5 5 0 Zinc ribbon domain Rpr2 PF04032.16 OQS06232.1 - 0.24 11.7 7.1 0.56 10.5 0.1 2.8 2 1 0 2 2 2 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain zf-NADH-PPase PF09297.11 OQS06232.1 - 0.27 10.9 15.1 1.7 8.3 0.1 4.2 4 0 0 4 4 4 0 NADH pyrophosphatase zinc ribbon domain zf-RING_7 PF02591.15 OQS06232.1 - 0.34 11.1 0.1 0.34 11.1 0.1 3.5 4 0 0 4 4 4 0 C4-type zinc ribbon domain RPA_interact_C PF14768.6 OQS06232.1 - 0.36 11.4 7.2 0.77 10.4 7.2 1.6 1 1 0 1 1 1 0 Replication protein A interacting C-terminal DNA_RNApol_7kD PF03604.13 OQS06232.1 - 0.47 10.2 15.8 0.32 10.7 1.5 3.1 3 0 0 3 3 3 0 DNA directed RNA polymerase, 7 kDa subunit DpnI PF06044.12 OQS06232.1 - 0.52 9.9 3.7 0.81 9.3 0.1 2.2 2 0 0 2 2 2 0 Dam-replacing family DUF4379 PF14311.6 OQS06232.1 - 0.73 10.2 0.1 0.73 10.2 0.1 3.5 3 1 0 4 4 3 0 Probable Zinc-ribbon domain GATA PF00320.27 OQS06232.1 - 0.75 9.5 10.2 2.9 7.6 0.3 3.6 2 1 1 3 3 3 0 GATA zinc finger PADR1 PF08063.12 OQS06232.1 - 0.81 9.5 11.4 1.7 8.5 0.1 3.1 3 0 0 3 3 3 0 PADR1 (NUC008) domain Terminase_GpA PF05876.12 OQS06232.1 - 0.84 8.1 7.6 0.067 11.7 1.1 2.0 1 1 0 2 2 2 0 Phage terminase large subunit (GpA) NOB1_Zn_bind PF08772.11 OQS06232.1 - 1.2 9.3 13.7 1.1 9.5 0.8 3.5 2 2 1 3 3 3 0 Nin one binding (NOB1) Zn-ribbon like Zn_ribbon_recom PF13408.6 OQS06232.1 - 1.5 9.4 10.8 3.9 8.1 1.1 3.6 3 1 0 3 3 3 0 Recombinase zinc beta ribbon domain TerY_C PF15616.6 OQS06232.1 - 2.1 8.4 9.4 1.7 8.8 1.7 2.6 1 1 1 2 2 2 0 TerY-C metal binding domain zf-C2HC5 PF06221.13 OQS06232.1 - 2.9 7.9 10.5 7.1 6.7 4.0 3.1 3 0 0 3 3 3 0 Putative zinc finger motif, C2HC5-type zf-RRN7 PF11781.8 OQS06232.1 - 5.6 6.7 17.2 5.8 6.7 4.5 4.3 3 1 0 3 3 3 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 zf_UBZ PF18439.1 OQS06232.1 - 6.2 6.5 15.0 6.2 6.5 0.1 4.2 4 0 0 4 4 4 0 Ubiquitin-Binding Zinc Finger DUF35_N PF12172.8 OQS06232.1 - 7.6 6.5 18.0 9.7 6.2 0.2 4.1 4 0 0 4 4 4 0 Rubredoxin-like zinc ribbon domain (DUF35_N) zf-FPG_IleRS PF06827.14 OQS06232.1 - 8.1 6.4 15.2 3.5 7.6 1.2 3.6 4 0 0 4 4 3 0 Zinc finger found in FPG and IleRS Peptidase_C1 PF00112.23 OQS06233.1 - 1.7e-44 152.5 1.8 2.8e-44 151.8 1.8 1.3 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.15 OQS06233.1 - 0.037 12.8 1.3 0.061 12.1 1.3 1.2 1 0 0 1 1 1 0 Peptidase C1-like family RCC1 PF00415.18 OQS06234.1 - 8.4e-83 272.9 13.1 1.3e-13 51.3 0.1 7.5 7 0 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 OQS06234.1 - 9.5e-30 101.8 46.0 1.4e-07 31.1 1.9 8.5 8 0 0 8 8 8 8 Regulator of chromosome condensation (RCC1) repeat Kelch_6 PF13964.6 OQS06234.1 - 0.083 13.2 2.7 4.6 7.7 0.1 3.4 2 0 0 2 2 2 0 Kelch motif PSS PF03034.15 OQS06235.1 - 8.8e-100 333.9 15.5 1.2e-99 333.5 15.5 1.2 1 0 0 1 1 1 1 Phosphatidyl serine synthase CcmH PF03918.14 OQS06235.1 - 0.13 11.5 0.0 11 5.4 0.0 2.5 2 0 0 2 2 2 0 Cytochrome C biogenesis protein Acetyltransf_3 PF13302.7 OQS06236.1 - 9.3e-17 62.0 0.1 1.1e-16 61.8 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 OQS06236.1 - 5.9e-10 39.4 0.0 9.3e-10 38.8 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.7 OQS06236.1 - 2e-08 34.5 0.0 3.3e-08 33.8 0.0 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain GAT PF03127.14 OQS06236.1 - 0.029 14.7 0.0 0.05 13.9 0.0 1.3 1 0 0 1 1 1 0 GAT domain Acetyltransf_7 PF13508.7 OQS06236.1 - 0.048 14.1 0.0 0.063 13.7 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 OQS06236.1 - 0.064 13.4 0.0 0.1 12.7 0.0 1.3 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Voltage_CLC PF00654.20 OQS06237.1 - 2.3e-53 181.7 34.1 2.4e-53 181.6 27.8 2.1 1 1 1 2 2 2 2 Voltage gated chloride channel SURNod19 PF07712.12 OQS06237.1 - 1.5e-47 162.2 6.8 4.8e-46 157.2 6.8 2.6 1 1 0 1 1 1 1 Stress up-regulated Nod 19 CBS PF00571.28 OQS06237.1 - 2.1e-08 34.5 0.3 0.0027 18.1 0.0 2.5 2 0 0 2 2 2 2 CBS domain DUF5627 PF18620.1 OQS06237.1 - 0.0023 17.8 0.0 0.0045 16.9 0.0 1.4 1 0 0 1 1 1 1 Family of unknown function (DUF5627) Pro_isomerase PF00160.21 OQS06238.1 - 5.2e-38 130.8 0.5 6.5e-38 130.5 0.5 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Ank_5 PF13857.6 OQS06240.1 - 1.2e-14 54.1 0.6 0.00093 19.5 0.0 4.2 3 1 1 4 4 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 OQS06240.1 - 1.7e-12 47.8 0.4 3.9e-07 30.5 0.1 2.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OQS06240.1 - 5.3e-12 44.8 3.4 0.029 14.9 0.0 5.7 7 0 0 7 7 6 3 Ankyrin repeat Ank_4 PF13637.6 OQS06240.1 - 1.4e-10 41.5 0.1 5.5e-05 23.6 0.0 4.3 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 OQS06240.1 - 2.1e-08 34.2 0.5 0.018 15.4 0.1 4.0 3 0 0 3 3 3 2 Ankyrin repeat FYVE PF01363.21 OQS06240.1 - 3.7e-07 30.2 4.2 6.5e-07 29.4 4.2 1.3 1 0 0 1 1 1 1 FYVE zinc finger Prok-RING_2 PF14445.6 OQS06240.1 - 0.0011 19.1 1.8 0.0011 19.1 1.8 1.8 2 0 0 2 2 2 1 Prokaryotic RING finger family 2 DUF4428 PF14471.6 OQS06240.1 - 0.042 13.8 5.3 0.12 12.4 5.3 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4428) Gin PF10764.9 OQS06240.1 - 0.68 9.9 4.0 1.4 8.9 4.0 1.5 1 0 0 1 1 1 0 Inhibitor of sigma-G Gin DUF2180 PF09947.9 OQS06240.1 - 0.86 9.6 5.6 3 7.9 5.8 1.8 1 1 1 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2180) FYVE_2 PF02318.16 OQS06240.1 - 2.1 8.6 8.0 7.9 6.7 7.5 1.9 1 1 1 2 2 2 0 FYVE-type zinc finger IBR PF01485.21 OQS06240.1 - 4.7 7.5 7.1 2 8.7 3.4 2.0 2 0 0 2 2 2 0 IBR domain, a half RING-finger domain PDZ_6 PF17820.1 OQS06241.1 - 0.025 14.4 0.0 0.077 12.9 0.0 1.9 1 0 0 1 1 1 0 PDZ domain Ank_2 PF12796.7 OQS06242.1 - 4.2e-45 152.2 5.1 4.7e-19 68.8 0.6 3.4 1 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.30 OQS06242.1 - 5.3e-42 140.5 15.6 1.3e-09 38.1 0.2 7.3 8 0 0 8 8 8 5 Ankyrin repeat Ank_4 PF13637.6 OQS06242.1 - 2.2e-38 130.1 7.5 5.9e-12 45.9 0.0 6.1 2 1 5 7 7 7 6 Ankyrin repeats (many copies) Ank_5 PF13857.6 OQS06242.1 - 3.3e-32 110.1 9.5 1.2e-11 44.6 0.1 5.0 2 2 3 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQS06242.1 - 3.7e-31 103.7 0.6 1.2e-06 28.3 0.0 6.0 6 0 0 6 6 6 5 Ankyrin repeat Imm_superinfect PF14373.6 OQS06242.1 - 0.12 12.3 0.8 1.1e+02 2.9 0.0 3.8 4 0 0 4 4 4 0 Superinfection immunity protein Carb_anhydrase PF00194.21 OQS06243.1 - 1.2e-17 64.3 0.1 1.3e-17 64.2 0.1 1.1 1 0 0 1 1 1 1 Eukaryotic-type carbonic anhydrase Carb_anhydrase PF00194.21 OQS06244.1 - 1.2e-35 123.3 0.0 2.4e-35 122.3 0.0 1.4 1 1 0 1 1 1 1 Eukaryotic-type carbonic anhydrase CA_like PF10563.9 OQS06244.1 - 1.3 8.9 3.4 23 4.9 3.4 2.5 1 1 0 1 1 1 0 Putative carbonic anhydrase SnoaL_2 PF12680.7 OQS06245.1 - 0.0005 20.7 0.0 0.00075 20.1 0.0 1.2 1 0 0 1 1 1 1 SnoaL-like domain SQHop_cyclase_C PF13243.6 OQS06246.1 - 3.9e-54 183.9 5.8 2e-46 158.6 6.7 2.3 2 0 0 2 2 2 2 Squalene-hopene cyclase C-terminal domain SQHop_cyclase_N PF13249.6 OQS06246.1 - 4e-52 177.1 0.4 2.9e-43 148.1 0.0 5.1 4 1 1 5 5 5 4 Squalene-hopene cyclase N-terminal domain Prenyltrans PF00432.21 OQS06246.1 - 1.4e-34 117.5 9.7 4.8e-10 39.0 0.2 6.9 7 0 0 7 7 7 6 Prenyltransferase and squalene oxidase repeat Pec_lyase PF09492.10 OQS06246.1 - 2e-06 27.4 3.8 1.7 7.9 0.2 4.9 5 0 0 5 5 5 3 Pectic acid lyase TED_complement PF07678.14 OQS06246.1 - 0.00067 18.8 0.5 0.038 13.0 0.1 3.3 1 1 2 3 3 3 1 A-macroglobulin TED domain Tim17 PF02466.19 OQS06246.1 - 0.17 12.2 0.3 0.46 10.9 0.1 1.9 2 0 0 2 2 2 0 Tim17/Tim22/Tim23/Pmp24 family ArfGap PF01412.18 OQS06247.1 - 2.4e-16 59.8 3.1 4e-16 59.1 3.1 1.4 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf PBAN PF05874.11 OQS06247.1 - 0.024 14.5 0.0 0.04 13.8 0.0 1.3 1 0 0 1 1 1 0 Pheromone biosynthesis activating neuropeptide (PBAN) Spt4 PF06093.13 OQS06247.1 - 0.036 14.2 1.8 0.077 13.1 1.8 1.6 1 0 0 1 1 1 0 Spt4/RpoE2 zinc finger PX PF00787.24 OQS06248.1 - 4.3e-09 36.4 0.2 8.7e-09 35.4 0.0 1.6 2 0 0 2 2 2 1 PX domain Carb_anhydrase PF00194.21 OQS06249.1 - 2.6e-75 253.2 0.9 1.9e-41 142.3 0.1 2.3 2 0 0 2 2 2 2 Eukaryotic-type carbonic anhydrase SCIMP PF15050.6 OQS06249.1 - 0.065 13.7 0.2 1.6 9.2 0.0 2.3 2 0 0 2 2 2 0 SCIMP protein Carb_anhydrase PF00194.21 OQS06250.1 - 3.6e-38 131.6 0.0 6.8e-38 130.7 0.0 1.4 1 1 0 1 1 1 1 Eukaryotic-type carbonic anhydrase RAP PF08373.10 OQS06251.1 - 2.4e-12 46.7 0.0 2.4e-12 46.7 0.0 1.8 2 0 0 2 2 2 1 RAP domain MTES_1575 PF18741.1 OQS06251.1 - 0.00012 22.2 0.0 0.00072 19.7 0.0 2.2 2 0 0 2 2 2 1 REase_MTES_1575 RIG-I_C-RD PF11648.8 OQS06251.1 - 0.0015 18.7 1.4 0.0091 16.2 0.1 2.6 2 0 0 2 2 2 1 C-terminal domain of RIG-I FAST_1 PF06743.15 OQS06251.1 - 0.096 12.6 2.3 16 5.6 0.0 3.7 2 1 2 4 4 4 0 FAST kinase-like protein, subdomain 1 DPPIV_N PF00930.21 OQS06252.1 - 2.3e-67 227.3 0.0 4.1e-65 219.9 0.0 2.3 1 1 1 2 2 2 2 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.21 OQS06252.1 - 9.6e-48 162.5 0.1 1.4e-47 162.0 0.1 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Peptidase_S15 PF02129.18 OQS06252.1 - 1e-10 41.7 2.5 2.1e-09 37.4 1.3 2.2 1 1 1 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) PD40 PF07676.12 OQS06252.1 - 0.00025 20.9 2.9 15 5.6 0.6 5.0 5 0 0 5 5 5 1 WD40-like Beta Propeller Repeat DLH PF01738.18 OQS06252.1 - 0.022 14.3 0.2 0.15 11.6 0.2 2.0 1 1 0 1 1 1 0 Dienelactone hydrolase family FSH1 PF03959.13 OQS06252.1 - 0.056 13.1 0.0 0.18 11.4 0.0 1.8 1 1 0 1 1 1 0 Serine hydrolase (FSH1) Esterase PF00756.20 OQS06252.1 - 0.07 12.8 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 Putative esterase Abhydrolase_6 PF12697.7 OQS06252.1 - 0.099 13.2 0.0 0.23 12.1 0.0 1.7 1 0 0 1 1 1 0 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 OQS06252.1 - 0.13 11.5 0.4 0.72 9.1 0.4 1.9 1 1 0 1 1 1 0 Serine aminopeptidase, S33 FYVE PF01363.21 OQS06254.1 - 7.1e-05 22.9 11.0 0.00015 21.9 11.0 1.5 1 0 0 1 1 1 1 FYVE zinc finger START PF01852.19 OQS06254.1 - 0.00096 18.6 0.0 0.0015 17.9 0.0 1.2 1 0 0 1 1 1 1 START domain FYVE_2 PF02318.16 OQS06254.1 - 0.0048 17.1 3.2 0.0093 16.2 3.2 1.5 1 0 0 1 1 1 1 FYVE-type zinc finger Prok-RING_4 PF14447.6 OQS06254.1 - 0.028 14.3 9.5 1.3 9.0 5.0 2.4 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 OQS06254.1 - 0.55 10.2 11.7 0.58 10.2 7.2 2.5 2 0 0 2 2 2 0 zinc-RING finger domain zf-RING_2 PF13639.6 OQS06254.1 - 7.5 7.0 13.8 1.9e+02 2.5 13.9 2.4 1 1 1 2 2 2 0 Ring finger domain FA_desaturase PF00487.24 OQS06256.1 - 3.6e-12 46.7 25.3 3.6e-12 46.7 25.3 1.9 2 1 0 2 2 2 1 Fatty acid desaturase DUF4293 PF14126.6 OQS06256.1 - 1.5 9.0 5.1 0.38 11.0 0.9 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4293) Peptidase_M20 PF01546.28 OQS06257.1 - 3.2e-25 89.0 0.0 4.3e-25 88.6 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 OQS06257.1 - 9e-10 38.4 0.2 2e-09 37.3 0.2 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain Ank_2 PF12796.7 OQS06258.1 - 1.9e-19 70.1 0.0 6e-10 39.6 0.0 2.4 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQS06258.1 - 9.5e-12 45.2 0.5 1.7e-09 38.0 0.1 3.6 2 1 2 4 4 4 2 Ankyrin repeats (many copies) Ank PF00023.30 OQS06258.1 - 3.7e-09 36.6 0.0 0.00026 21.3 0.0 3.5 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 OQS06258.1 - 2.4e-07 30.9 0.2 1.6e-05 25.1 0.1 2.6 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQS06258.1 - 7.1e-07 29.1 0.0 0.031 14.8 0.0 3.9 4 0 0 4 4 4 2 Ankyrin repeat FYVE PF01363.21 OQS06258.1 - 3e-05 24.1 11.3 7.8e-05 22.7 11.3 1.8 1 0 0 1 1 1 1 FYVE zinc finger PH PF00169.29 OQS06258.1 - 0.00081 19.9 0.1 0.0024 18.4 0.1 1.9 1 0 0 1 1 1 1 PH domain zf-C3HC4_3 PF13920.6 OQS06258.1 - 0.016 15.1 2.0 0.016 15.1 2.0 3.3 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) H_PPase PF03030.16 OQS06259.1 - 2.9e-240 799.4 33.6 3.6e-240 799.1 33.6 1.1 1 0 0 1 1 1 1 Inorganic H+ pyrophosphatase Ribosomal_L1 PF00687.21 OQS06260.1 - 1.8e-37 129.1 5.5 3.3e-37 128.2 5.5 1.3 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family RNA_pol_Rpb4 PF03874.16 OQS06260.1 - 0.012 15.9 0.3 0.054 13.8 0.2 2.2 2 0 0 2 2 2 0 RNA polymerase Rpb4 NUDIX PF00293.28 OQS06261.1 - 0.09 12.8 0.2 0.24 11.4 0.2 1.8 1 1 0 1 1 1 0 NUDIX domain PLDc_2 PF13091.6 OQS06261.1 - 0.14 12.0 0.0 0.29 11.0 0.0 1.5 1 0 0 1 1 1 0 PLD-like domain NUDIX_4 PF14815.6 OQS06261.1 - 0.15 12.1 0.0 0.62 10.1 0.0 1.9 1 1 0 1 1 1 0 NUDIX domain Elicitin PF00964.17 OQS06262.1 - 6.7e-07 29.3 6.1 0.00036 20.6 0.4 5.1 6 0 0 6 6 6 2 Elicitin DIM PF08194.12 OQS06262.1 - 6 7.2 6.6 40 4.5 1.0 3.2 2 0 0 2 2 2 0 DIM protein Methyltransf_7 PF03492.15 OQS06263.1 - 1.2e-47 162.8 0.0 1.5e-47 162.4 0.0 1.1 1 0 0 1 1 1 1 SAM dependent carboxyl methyltransferase Citrate_synt PF00285.21 OQS06263.1 - 0.13 11.3 0.0 0.19 10.7 0.0 1.1 1 0 0 1 1 1 0 Citrate synthase, C-terminal domain DUF4042 PF13251.6 OQS06264.1 - 8.1e-17 61.5 17.5 7.2e-16 58.4 8.7 5.6 4 2 0 4 4 4 1 Domain of unknown function (DUF4042) HEAT_2 PF13646.6 OQS06264.1 - 7.5e-11 42.3 0.9 0.0028 18.0 0.0 6.6 4 2 3 7 7 7 3 HEAT repeats HEAT PF02985.22 OQS06264.1 - 6.2e-10 38.5 15.2 2.2 8.8 0.0 10.9 11 0 0 11 11 11 2 HEAT repeat HEAT_EZ PF13513.6 OQS06264.1 - 1.4e-05 25.5 3.5 4.2 8.0 0.0 6.7 6 1 1 7 7 7 2 HEAT-like repeat Vac14_Fab1_bd PF12755.7 OQS06264.1 - 0.00059 20.4 0.1 3.8 8.2 0.1 5.5 4 3 2 6 6 6 1 Vacuolar 14 Fab1-binding region IFRD PF05004.13 OQS06264.1 - 0.00097 18.3 7.6 1.6 7.8 0.2 4.4 4 1 1 5 5 5 2 Interferon-related developmental regulator (IFRD) RTP1_C1 PF10363.9 OQS06264.1 - 0.024 14.8 0.7 4.5 7.5 0.0 4.5 4 2 0 5 5 5 0 Required for nuclear transport of RNA pol II C-terminus 1 EGF_2 PF07974.13 OQS06265.1 - 3.1e-10 40.2 57.9 0.00012 22.4 5.6 5.4 5 0 0 5 5 5 5 EGF-like domain Laminin_EGF PF00053.24 OQS06265.1 - 3e-05 24.1 45.7 0.12 12.5 5.5 4.6 3 1 1 4 4 4 4 Laminin EGF domain Inositol_P PF00459.25 OQS06266.1 - 4.2e-60 203.6 0.7 5e-60 203.3 0.7 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family FBPase_glpX PF03320.13 OQS06266.1 - 0.0078 15.1 0.1 0.025 13.5 0.0 1.7 1 1 0 1 1 1 1 Bacterial fructose-1,6-bisphosphatase, glpX-encoded IlvC PF01450.19 OQS06267.1 - 1.8e-38 132.0 0.0 1.3e-28 100.1 0.0 2.2 2 0 0 2 2 2 2 Acetohydroxy acid isomeroreductase, catalytic domain IlvN PF07991.12 OQS06267.1 - 9.9e-35 119.5 0.1 1.8e-34 118.7 0.1 1.4 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain Pkinase PF00069.25 OQS06268.1 - 2.7e-69 233.5 0.0 3.3e-69 233.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQS06268.1 - 1.3e-31 109.9 0.0 1.6e-31 109.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OQS06268.1 - 1.7e-06 27.6 0.0 0.0018 17.6 0.0 2.3 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.14 OQS06268.1 - 0.00018 21.0 0.1 0.00028 20.3 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OQS06268.1 - 0.00069 19.6 0.6 0.034 14.1 0.1 2.6 2 1 1 3 3 3 1 Phosphotransferase enzyme family UCH PF00443.29 OQS06269.1 - 2.3e-45 155.1 0.1 5.4e-45 153.9 0.0 1.7 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 OQS06269.1 - 1.8e-18 67.2 1.4 1.8e-17 63.9 1.4 2.5 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase PIG-P PF08510.12 OQS06270.1 - 7.4e-37 126.0 6.6 8.9e-37 125.7 6.6 1.1 1 0 0 1 1 1 1 PIG-P DPM2 PF07297.12 OQS06270.1 - 1.2e-05 25.5 6.8 2.2e-05 24.7 6.8 1.4 1 0 0 1 1 1 1 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) FixQ PF05545.11 OQS06270.1 - 0.1 12.6 0.8 0.1 12.6 0.8 1.9 2 0 0 2 2 2 0 Cbb3-type cytochrome oxidase component FixQ PHP PF02811.19 OQS06271.1 - 2.7e-08 34.3 0.0 3.2e-08 34.1 0.0 1.3 1 1 0 1 1 1 1 PHP domain Pkinase PF00069.25 OQS06272.1 - 4.1e-65 219.8 0.0 4.8e-65 219.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQS06272.1 - 4.1e-27 95.1 0.0 5.6e-27 94.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 OQS06272.1 - 0.00033 20.1 0.2 0.00056 19.3 0.2 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 OQS06272.1 - 0.00036 19.9 0.0 0.0092 15.3 0.0 2.2 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 OQS06272.1 - 0.00067 19.6 1.3 0.0015 18.5 0.1 1.9 2 1 1 3 3 3 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 OQS06272.1 - 0.13 11.9 0.0 0.23 11.0 0.0 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase Mod_r PF07200.13 OQS06273.1 - 0.012 15.7 13.4 0.31 11.1 0.3 3.5 3 0 0 3 3 3 0 Modifier of rudimentary (Mod(r)) protein OmpH PF03938.14 OQS06273.1 - 0.054 13.8 9.3 0.054 13.8 0.9 2.6 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) SH3BP5 PF05276.14 OQS06273.1 - 0.057 13.2 12.0 0.22 11.3 0.3 3.3 2 1 1 3 3 3 0 SH3 domain-binding protein 5 (SH3BP5) DUF745 PF05335.13 OQS06273.1 - 0.14 11.9 16.6 2.5 7.8 3.2 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF745) Prp19 PF08606.11 OQS06273.1 - 0.29 11.2 0.1 0.29 11.2 0.1 3.0 3 0 0 3 3 3 0 Prp19/Pso4-like CASP_C PF08172.12 OQS06274.1 - 1.9e-33 115.9 19.0 1.9e-33 115.9 19.0 4.3 1 1 2 3 3 3 1 CASP C terminal Lebercilin PF15619.6 OQS06274.1 - 0.0015 18.2 5.4 0.0015 18.2 5.4 5.4 2 1 1 5 5 5 2 Ciliary protein causing Leber congenital amaurosis disease TMF_DNA_bd PF12329.8 OQS06274.1 - 0.35 10.9 0.1 0.35 10.9 0.1 6.7 5 1 1 6 6 6 0 TATA element modulatory factor 1 DNA binding DUF2721 PF11026.8 OQS06274.1 - 0.58 10.1 0.1 0.58 10.1 0.1 4.4 4 0 0 4 4 4 0 Protein of unknown function (DUF2721) ATG16 PF08614.11 OQS06274.1 - 0.86 9.8 58.6 0.098 12.9 4.8 5.3 2 1 0 5 5 5 0 Autophagy protein 16 (ATG16) YgbB PF02542.16 OQS06274.1 - 0.94 9.8 2.8 1.6 9.0 0.2 2.6 2 1 1 3 3 3 0 YgbB family LURAP PF14854.6 OQS06274.1 - 1.5 8.8 9.4 8.4 6.4 0.3 3.8 4 0 0 4 4 4 0 Leucine rich adaptor protein FlaC_arch PF05377.11 OQS06274.1 - 4.2 7.8 21.2 5.4 7.5 0.1 6.2 5 2 0 5 5 5 0 Flagella accessory protein C (FlaC) DUF4315 PF14193.6 OQS06274.1 - 7.8 6.6 20.7 0.35 10.9 0.8 4.9 4 2 0 4 4 4 0 Domain of unknown function (DUF4315) Peptidase_S24 PF00717.23 OQS06275.1 - 4.1e-09 36.3 0.1 9.5e-09 35.1 0.1 1.6 1 1 0 1 1 1 1 Peptidase S24-like Uma2 PF05685.12 OQS06275.1 - 0.063 12.8 0.0 0.087 12.4 0.0 1.2 1 0 0 1 1 1 0 Putative restriction endonuclease Peptidase_S26 PF10502.9 OQS06275.1 - 0.086 12.6 0.0 13 5.5 0.0 2.8 1 1 1 2 2 2 0 Signal peptidase, peptidase S26 Ribosomal_L34 PF00468.17 OQS06275.1 - 0.12 12.3 0.9 0.12 12.3 0.9 2.3 3 0 0 3 3 3 0 Ribosomal protein L34 Tetraspanin PF00335.20 OQS06276.1 - 7.7e-10 38.9 5.3 1.1e-09 38.4 5.3 1.3 1 1 0 1 1 1 1 Tetraspanin family DUF573 PF04504.14 OQS06276.1 - 0.059 14.0 1.4 0.1 13.2 1.4 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF573 TMEM174 PF15029.6 OQS06276.1 - 0.58 9.8 4.1 1.1 9.0 4.1 1.5 1 0 0 1 1 1 0 Transmembrane protein 174 PDZ_6 PF17820.1 OQS06278.1 - 0.011 15.5 0.0 1.1 9.2 0.0 2.3 2 0 0 2 2 2 0 PDZ domain TetR_C_4 PF08359.11 OQS06279.1 - 0.055 13.6 0.5 0.1 12.7 0.5 1.5 1 0 0 1 1 1 0 YsiA-like protein, C-terminal region LRR_4 PF12799.7 OQS06280.1 - 4.2e-15 55.6 16.2 1.6e-06 28.4 6.0 5.1 3 1 2 5 5 5 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 OQS06280.1 - 1.4e-11 44.0 14.9 6.9e-09 35.3 4.9 4.7 2 1 3 5 5 5 4 Leucine rich repeat LRR_9 PF14580.6 OQS06280.1 - 2.3e-09 37.0 5.4 8.3e-06 25.4 0.2 3.0 2 1 1 3 3 3 2 Leucine-rich repeat IL32 PF15225.6 OQS06280.1 - 0.032 14.6 0.4 0.073 13.4 0.4 1.6 1 0 0 1 1 1 0 Interleukin 32 Csm1_N PF18504.1 OQS06280.1 - 1.7 9.1 11.9 1.4 9.3 5.7 3.7 2 1 1 3 3 3 0 Csm1 N-terminal domain YabA PF06156.13 OQS06280.1 - 1.8 9.2 16.8 0.34 11.6 4.7 3.9 2 1 2 4 4 4 0 Initiation control protein YabA LRR_6 PF13516.6 OQS06280.1 - 4.1 7.7 7.4 66 3.9 0.3 4.5 4 0 0 4 4 4 0 Leucine Rich repeat DUF1640 PF07798.11 OQS06280.1 - 4.5 7.3 11.2 10 6.1 11.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) TPR_12 PF13424.6 OQS06281.1 - 1.3e-14 54.2 15.3 3.2e-05 24.1 1.7 4.3 2 1 3 5 5 5 4 Tetratricopeptide repeat TPR_1 PF00515.28 OQS06281.1 - 1e-07 31.4 20.1 0.3 11.0 0.4 6.2 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_7 PF13176.6 OQS06281.1 - 2.3e-07 30.4 9.2 0.15 12.1 0.1 5.5 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_2 PF07719.17 OQS06281.1 - 1.4e-06 27.9 21.0 0.4 10.9 0.5 6.3 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_8 PF13181.6 OQS06281.1 - 2.8e-06 27.1 17.0 0.48 10.8 0.0 5.9 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_MalT PF17874.1 OQS06281.1 - 5.7e-05 22.6 4.4 0.0001 21.8 3.7 1.7 1 1 1 2 2 2 1 MalT-like TPR region TPR_14 PF13428.6 OQS06281.1 - 0.00017 22.1 8.0 0.06 14.2 0.4 5.2 3 2 3 6 6 6 1 Tetratricopeptide repeat TPR_10 PF13374.6 OQS06281.1 - 0.011 15.6 8.6 1.6 8.7 0.1 4.8 5 0 0 5 5 5 0 Tetratricopeptide repeat DUF273 PF03314.14 OQS06281.1 - 0.092 12.3 0.2 0.18 11.3 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF273 DUF4807 PF16065.5 OQS06281.1 - 0.093 12.4 0.1 0.32 10.6 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4807) TPR_19 PF14559.6 OQS06281.1 - 0.097 13.2 8.4 2 9.0 0.4 3.9 2 1 2 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.6 OQS06281.1 - 0.15 12.8 13.4 36 5.3 0.0 6.0 6 0 0 6 6 6 0 Tetratricopeptide repeat ANAPC3 PF12895.7 OQS06281.1 - 0.84 9.9 11.8 1.1 9.6 0.9 3.6 2 1 1 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.6 OQS06281.1 - 4 8.0 6.4 70 4.1 0.1 4.3 4 1 0 4 4 3 0 Tetratricopeptide repeat DUF3153 PF11353.8 OQS06282.1 - 0.0028 17.2 3.4 0.0047 16.5 3.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3153) Med29 PF11568.8 OQS06282.1 - 0.5 10.6 8.1 0.16 12.2 4.5 1.9 2 0 0 2 2 2 0 Mediator complex subunit 29 Glucan_synthase PF02364.15 OQS06283.1 - 2.7e-173 578.3 9.4 1.2e-151 506.7 3.8 2.4 1 1 1 2 2 2 2 1,3-beta-glucan synthase component FKS1_dom1 PF14288.6 OQS06283.1 - 9.4e-24 84.2 4.5 2.2e-22 79.8 1.8 3.2 2 1 0 2 2 2 1 1,3-beta-glucan synthase subunit FKS1, domain-1 TPR_12 PF13424.6 OQS06283.1 - 0.0025 18.1 0.1 0.11 12.8 0.0 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TROVE PF05731.11 OQS06283.1 - 0.014 14.4 0.0 0.028 13.5 0.0 1.4 1 0 0 1 1 1 0 TROVE domain MIT PF04212.18 OQS06283.1 - 0.022 14.8 0.2 0.055 13.5 0.2 1.7 1 0 0 1 1 1 0 MIT (microtubule interacting and transport) domain EF-hand_5 PF13202.6 OQS06283.1 - 0.046 13.2 0.0 1.3 8.6 0.0 2.7 2 0 0 2 2 2 0 EF hand TPR_1 PF00515.28 OQS06283.1 - 0.14 12.1 0.0 1 9.3 0.0 2.6 3 0 0 3 3 3 0 Tetratricopeptide repeat NAD_binding_1 PF00175.21 OQS06284.1 - 3e-31 108.3 0.0 5.5e-31 107.4 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 OQS06284.1 - 2.4e-24 85.6 0.0 4e-24 84.8 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 OQS06284.1 - 4.8e-07 30.0 0.0 8.6e-05 22.7 0.0 2.4 1 1 0 2 2 2 2 Ferric reductase NAD binding domain TTL PF03133.15 OQS06285.1 - 1.1e-36 126.4 2.1 1.4e-36 126.1 2.1 1.1 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 OQS06285.1 - 3.2e-06 26.6 0.1 0.047 12.9 0.0 2.9 2 1 0 2 2 2 2 YheC/D like ATP-grasp FERM_M PF00373.18 OQS06285.1 - 0.029 14.8 0.4 0.43 11.0 0.1 2.2 2 1 0 2 2 2 0 FERM central domain GSH-S_ATP PF02955.16 OQS06285.1 - 0.13 11.7 0.0 0.19 11.1 0.0 1.2 1 0 0 1 1 1 0 Prokaryotic glutathione synthetase, ATP-grasp domain FragX_IP PF05994.11 OQS06286.1 - 5.2e-150 501.2 16.0 5.1e-141 471.4 13.6 2.3 1 1 1 2 2 2 2 Cytoplasmic Fragile-X interacting family DUF1394 PF07159.12 OQS06286.1 - 0.0003 20.1 1.4 0.00067 19.0 1.4 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1394) XLF PF09302.11 OQS06286.1 - 0.059 13.5 4.3 0.048 13.8 1.9 2.1 2 0 0 2 2 2 0 XLF-Cernunnos, XRcc4-like factor, NHEJ component Vasohibin PF14822.6 OQS06287.1 - 8.8e-60 202.0 0.1 1.5e-59 201.3 0.1 1.2 1 0 0 1 1 1 1 Vasohibin MatE PF01554.18 OQS06288.1 - 6.6e-51 172.2 38.8 6e-27 94.3 12.8 2.6 3 0 0 3 3 3 2 MatE DUF2208 PF09973.9 OQS06288.1 - 0.014 15.0 2.1 0.014 15.0 2.1 2.6 2 1 1 3 3 3 0 Predicted membrane protein (DUF2208) Glucan_synthase PF02364.15 OQS06289.1 - 2.5e-185 618.1 18.9 1.3e-162 543.0 11.4 2.9 1 1 1 2 2 2 2 1,3-beta-glucan synthase component FKS1_dom1 PF14288.6 OQS06289.1 - 3.6e-21 75.8 11.5 8.5e-21 74.6 1.0 5.0 5 1 0 5 5 5 1 1,3-beta-glucan synthase subunit FKS1, domain-1 MIT PF04212.18 OQS06289.1 - 0.0011 19.0 2.0 0.0031 17.5 2.0 1.9 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain EF-hand_5 PF13202.6 OQS06289.1 - 0.0027 17.1 0.1 0.55 9.8 0.0 3.5 3 0 0 3 3 3 1 EF hand Fig1 PF12351.8 OQS06289.1 - 0.03 14.3 1.1 0.086 12.8 1.1 1.7 1 0 0 1 1 1 0 Ca2+ regulator and membrane fusion protein Fig1 THP2 PF09432.10 OQS06289.1 - 0.038 14.0 0.1 0.12 12.5 0.1 1.8 1 0 0 1 1 1 0 Tho complex subunit THP2 TB2_DP1_HVA22 PF03134.19 OQS06290.1 - 5e-17 61.6 3.7 5e-17 61.6 3.7 1.7 2 0 0 2 2 2 1 TB2/DP1, HVA22 family Peptidase_M50B PF13398.6 OQS06291.1 - 2.8e-53 180.6 18.7 2.8e-53 180.6 18.7 1.4 2 0 0 2 2 2 1 Peptidase M50B-like Kinesin PF00225.23 OQS06292.1 - 1.2e-87 294.0 0.4 1.2e-87 294.0 0.4 1.8 3 0 0 3 3 3 1 Kinesin motor domain Microtub_bd PF16796.5 OQS06292.1 - 9.1e-14 51.6 0.1 2.5e-13 50.2 0.1 1.8 1 0 0 1 1 1 1 Microtubule binding AAA_16 PF13191.6 OQS06292.1 - 0.054 13.9 0.5 0.44 10.9 0.0 2.7 2 1 0 2 2 2 0 AAA ATPase domain AAA_22 PF13401.6 OQS06292.1 - 0.29 11.4 3.2 0.59 10.4 0.0 3.1 4 1 1 5 5 5 0 AAA domain DUF87 PF01935.17 OQS06292.1 - 0.38 10.8 2.9 2.1 8.4 0.0 2.9 3 0 0 3 3 3 0 Helicase HerA, central domain TB2_DP1_HVA22 PF03134.19 OQS06293.1 - 1.9e-30 104.6 8.8 2.8e-30 104.1 8.8 1.3 1 0 0 1 1 1 1 TB2/DP1, HVA22 family FA_desaturase PF00487.24 OQS06293.1 - 3.4 7.4 8.1 6 6.6 7.9 1.3 1 1 0 1 1 1 0 Fatty acid desaturase UQ_con PF00179.26 OQS06294.1 - 5.6e-16 58.5 0.0 8.3e-16 57.9 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 OQS06294.1 - 0.029 14.1 0.0 0.065 12.9 0.0 1.7 2 0 0 2 2 2 0 Prokaryotic E2 family B HSP20 PF00011.21 OQS06296.1 - 0.00043 20.4 1.1 0.0018 18.4 0.0 2.4 1 1 1 3 3 3 1 Hsp20/alpha crystallin family DUF4358 PF14270.6 OQS06296.1 - 0.032 14.5 3.1 0.032 14.5 3.1 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4358) SlyX PF04102.12 OQS06296.1 - 0.078 13.6 23.5 0.15 12.7 8.8 4.0 2 1 1 3 3 3 0 SlyX NLRC4_HD2 PF17776.1 OQS06296.1 - 0.12 13.0 0.1 0.12 13.0 0.1 2.3 2 1 0 2 2 2 0 NLRC4 helical domain HD2 PKcGMP_CC PF16808.5 OQS06296.1 - 0.13 12.1 21.5 0.19 11.6 2.5 4.0 2 1 1 3 3 3 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Sp38 PF07354.12 OQS06296.1 - 0.14 11.6 1.0 0.21 11.0 1.0 1.2 1 0 0 1 1 1 0 Zona-pellucida-binding protein (Sp38) DUF4686 PF15742.5 OQS06296.1 - 0.15 11.2 25.1 0.3 10.2 24.7 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4686) Reovirus_cap PF00979.17 OQS06296.1 - 0.15 11.2 1.6 0.21 10.7 1.6 1.2 1 0 0 1 1 1 0 Reovirus outer capsid protein, Sigma 3 Phlebovirus_NSM PF07246.11 OQS06296.1 - 0.52 9.7 10.7 0.93 8.8 10.7 1.4 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M Exonuc_VII_L PF02601.15 OQS06296.1 - 0.73 9.3 8.9 1 8.9 8.9 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit Spc29 PF17082.5 OQS06296.1 - 1.4 8.7 12.4 1.5 8.6 11.1 1.7 1 1 1 2 2 2 0 Spindle Pole Component 29 DUF4407 PF14362.6 OQS06296.1 - 3.5 6.9 7.0 4.5 6.5 7.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) PH PF00169.29 OQS06297.1 - 7.5e-05 23.2 0.0 0.00039 20.9 0.0 2.3 2 0 0 2 2 2 1 PH domain SnoaL_2 PF12680.7 OQS06297.1 - 0.0011 19.5 0.0 0.012 16.3 0.0 2.4 2 0 0 2 2 2 1 SnoaL-like domain Ipi1_N PF12333.8 OQS06297.1 - 0.042 14.4 0.0 2.2 8.9 0.0 2.7 2 0 0 2 2 2 0 Rix1 complex component involved in 60S ribosome maturation SAPS PF04499.15 OQS06297.1 - 1.5 7.5 6.9 0.17 10.6 0.1 2.6 1 1 1 2 2 2 0 SIT4 phosphatase-associated protein Metaviral_G PF09595.10 OQS06298.1 - 1.6 8.7 4.4 0.67 10.0 0.2 2.0 2 0 0 2 2 2 0 Metaviral_G glycoprotein Mito_carr PF00153.27 OQS06299.1 - 5.8e-26 90.2 1.4 3.5e-13 49.3 0.0 3.5 3 0 0 3 3 3 3 Mitochondrial carrier protein zf-TRAF PF02176.18 OQS06300.1 - 3.6e-18 66.0 72.9 0.00069 20.3 5.0 7.5 6 2 1 7 7 7 6 TRAF-type zinc finger Laminin_G_3 PF13385.6 OQS06300.1 - 5.8e-06 26.5 0.0 1.6e-05 25.1 0.0 1.7 2 0 0 2 2 2 1 Concanavalin A-like lectin/glucanases superfamily DUF1080 PF06439.11 OQS06300.1 - 0.15 12.2 0.0 0.43 10.7 0.0 1.8 1 1 0 1 1 1 0 Domain of Unknown Function (DUF1080) Tudor-knot PF11717.8 OQS06300.1 - 0.44 10.5 2.4 10 6.1 0.1 3.2 3 0 0 3 3 3 0 RNA binding activity-knot of a chromodomain DUF4570 PF15134.6 OQS06300.1 - 4.6 7.3 6.4 5.4 7.1 1.6 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4570) Peptidase_M28 PF04389.17 OQS06301.1 - 2.3e-35 122.1 0.0 3.6e-35 121.5 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 DNA_gyraseA_C PF03989.13 OQS06301.1 - 0.071 12.6 0.2 2.5 7.7 0.0 2.7 2 0 0 2 2 2 0 DNA gyrase C-terminal domain, beta-propeller HTH_37 PF13744.6 OQS06302.1 - 0.009 16.0 2.4 0.027 14.4 2.0 2.1 2 0 0 2 2 2 1 Helix-turn-helix domain DUF641 PF04859.12 OQS06302.1 - 0.019 15.3 3.1 0.019 15.3 3.1 2.0 2 0 0 2 2 2 0 Plant protein of unknown function (DUF641) SBP_bac_3 PF00497.20 OQS06302.1 - 0.042 13.3 0.0 0.096 12.1 0.0 1.5 1 0 0 1 1 1 0 Bacterial extracellular solute-binding proteins, family 3 HEPN_Swt1 PF18731.1 OQS06302.1 - 0.44 10.9 4.2 1.4 9.3 0.1 3.2 3 0 0 3 3 3 0 Swt1-like HEPN Mg_chelatase_C PF13335.6 OQS06302.1 - 0.61 10.8 3.1 0.96 10.1 1.7 2.2 1 1 1 2 2 2 0 Magnesium chelatase, subunit ChlI C-terminal zf-C2H2 PF00096.26 OQS06304.1 - 0.061 13.8 0.3 0.16 12.5 0.3 1.8 1 0 0 1 1 1 0 Zinc finger, C2H2 type MoCF_biosynth PF00994.24 OQS06305.1 - 6.8e-59 197.7 0.3 4e-31 107.6 0.1 2.4 2 0 0 2 2 2 2 Probable molybdopterin binding domain eRF1_2 PF03464.15 OQS06305.1 - 2.4e-43 147.7 0.1 4.2e-43 146.9 0.1 1.4 1 0 0 1 1 1 1 eRF1 domain 2 MoeA_N PF03453.17 OQS06305.1 - 2.1e-40 138.1 0.8 3.4e-40 137.4 0.8 1.4 1 0 0 1 1 1 1 MoeA N-terminal region (domain I and II) eRF1_3 PF03465.15 OQS06305.1 - 5e-36 123.6 0.0 1.1e-35 122.5 0.0 1.6 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_1 PF03463.15 OQS06305.1 - 5e-19 68.6 0.0 9.4e-19 67.7 0.0 1.4 1 0 0 1 1 1 1 eRF1 domain 1 MoeA_C PF03454.15 OQS06305.1 - 1.2e-13 51.1 0.1 5.5e-13 48.9 0.0 2.3 2 0 0 2 2 2 1 MoeA C-terminal region (domain IV) baeRF_family10 PF18854.1 OQS06305.1 - 1.2e-10 41.8 0.0 8.5e-10 39.0 0.0 2.3 2 0 0 2 2 2 1 Bacterial archaeo-eukaryotic release factor family 10 acVLRF1 PF18859.1 OQS06305.1 - 1.4e-09 38.3 0.0 3.1e-09 37.2 0.0 1.6 1 0 0 1 1 1 1 Actinobacteria/chloroflexi VLRF1 release factor 7TMR-HDED PF07697.11 OQS06305.1 - 0.027 14.6 0.1 0.059 13.5 0.1 1.6 1 0 0 1 1 1 0 7TM-HD extracellular Pkinase_Tyr PF07714.17 OQS06306.1 - 7.4e-40 136.9 0.0 1.1e-39 136.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OQS06306.1 - 2.4e-37 128.8 0.0 2.5e-28 99.2 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain LRR_8 PF13855.6 OQS06306.1 - 9e-11 41.4 28.9 3.3e-05 23.6 0.7 4.4 1 1 6 7 7 7 7 Leucine rich repeat LRR_6 PF13516.6 OQS06306.1 - 8.2e-09 34.8 2.7 4.6 7.5 0.0 5.9 5 0 0 5 5 5 3 Leucine Rich repeat LRR_4 PF12799.7 OQS06306.1 - 2.9e-08 33.9 21.1 0.0047 17.3 0.3 5.8 3 2 3 6 6 6 4 Leucine Rich repeats (2 copies) Pkinase_fungal PF17667.1 OQS06306.1 - 0.00056 18.8 0.0 0.00094 18.1 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase LRR_9 PF14580.6 OQS06306.1 - 0.0013 18.2 2.7 0.033 13.7 0.2 2.5 1 1 1 2 2 2 1 Leucine-rich repeat LRR_1 PF00560.33 OQS06306.1 - 0.31 11.7 8.8 31 5.6 0.1 6.1 5 2 1 6 6 6 0 Leucine Rich Repeat FNIP PF05725.12 OQS06306.1 - 0.65 10.2 9.2 2.7 8.3 0.4 3.6 3 0 0 3 3 3 0 FNIP Repeat NPCC PF08058.11 OQS06307.1 - 2.3 8.3 6.3 0.14 12.2 0.6 1.8 2 1 0 2 2 2 0 Nuclear pore complex component WD40 PF00400.32 OQS06308.1 - 1.2e-48 162.0 9.3 3.6e-08 33.9 0.0 7.4 7 0 0 7 7 7 7 WD domain, G-beta repeat Tup_N PF08581.10 OQS06308.1 - 2.8e-20 72.4 10.1 4.4e-20 71.8 10.1 1.3 1 0 0 1 1 1 1 Tup N-terminal ANAPC4_WD40 PF12894.7 OQS06308.1 - 7.2e-15 55.1 0.0 0.0031 17.8 0.0 6.0 1 1 5 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 OQS06308.1 - 3.8e-09 36.0 0.0 0.18 10.7 0.0 4.5 1 1 4 5 5 5 4 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 OQS06308.1 - 1.7e-05 24.6 0.0 45 4.1 0.0 5.5 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat Nbas_N PF15492.6 OQS06308.1 - 5.2e-05 22.7 0.0 0.75 9.1 0.0 3.6 3 1 1 4 4 4 2 Neuroblastoma-amplified sequence, N terminal CENP-Q PF13094.6 OQS06308.1 - 0.0017 18.6 0.1 0.0043 17.3 0.1 1.7 1 0 0 1 1 1 1 CENP-Q, a CENPA-CAD centromere complex subunit WD40_like PF17005.5 OQS06308.1 - 0.0059 16.0 0.0 12 5.2 0.0 3.2 3 0 0 3 3 3 1 WD40-like domain Nup160 PF11715.8 OQS06308.1 - 0.01 14.5 0.0 0.085 11.5 0.0 2.2 2 0 0 2 2 2 0 Nucleoporin Nup120/160 Filament PF00038.21 OQS06308.1 - 0.011 15.4 6.2 0.017 14.7 6.2 1.1 1 0 0 1 1 1 0 Intermediate filament protein BAR_3 PF16746.5 OQS06308.1 - 0.074 12.8 2.5 0.12 12.1 2.5 1.2 1 0 0 1 1 1 0 BAR domain of APPL family Proteasome_A_N PF10584.9 OQS06308.1 - 0.42 10.3 2.7 85 3.0 0.1 4.1 4 0 0 4 4 4 0 Proteasome subunit A N-terminal signature DUF3450 PF11932.8 OQS06308.1 - 0.83 8.9 7.3 1.5 8.0 7.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) zf-C4H2 PF10146.9 OQS06308.1 - 1.3 9.3 10.3 0.16 12.2 4.4 2.1 2 0 0 2 2 2 0 Zinc finger-containing protein DUF1664 PF07889.12 OQS06308.1 - 1.6 8.8 3.9 2.7 8.1 3.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Laminin_II PF06009.12 OQS06309.1 - 0.0034 17.4 2.2 0.012 15.6 0.8 2.2 2 0 0 2 2 2 1 Laminin Domain II Topoisom_I PF01028.20 OQS06309.1 - 0.007 15.6 1.2 0.0099 15.1 1.2 1.2 1 0 0 1 1 1 1 Eukaryotic DNA topoisomerase I, catalytic core DUF1664 PF07889.12 OQS06309.1 - 0.029 14.4 1.4 2.6 8.1 1.0 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) DUF4795 PF16043.5 OQS06309.1 - 0.042 13.5 6.0 0.052 13.2 1.8 2.2 1 1 0 2 2 2 0 Domain of unknown function (DUF4795) DUF2730 PF10805.8 OQS06309.1 - 0.061 13.4 1.1 0.3 11.2 0.2 2.4 1 1 2 3 3 3 0 Protein of unknown function (DUF2730) Fib_alpha PF08702.10 OQS06309.1 - 0.074 13.2 4.5 0.36 11.0 1.2 2.8 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family RasGAP_C PF03836.15 OQS06309.1 - 0.12 12.6 2.6 0.18 11.9 1.6 2.0 2 1 0 2 2 2 0 RasGAP C-terminus SBDS_C PF09377.10 OQS06309.1 - 0.14 12.2 1.3 3.2 7.8 0.2 2.4 1 1 0 2 2 2 0 SBDS protein C-terminal domain Mis12 PF05859.12 OQS06309.1 - 0.46 10.5 4.7 0.22 11.6 0.6 2.4 2 1 2 4 4 4 0 Mis12 protein DUF4200 PF13863.6 OQS06309.1 - 4.6 7.7 7.5 1 9.8 3.6 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) DSPc PF00782.20 OQS06310.1 - 4.5e-32 110.6 0.1 7.9e-32 109.9 0.1 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 OQS06310.1 - 0.00055 19.6 0.0 0.0008 19.0 0.0 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase CDKN3 PF05706.12 OQS06310.1 - 0.0049 16.6 0.2 0.0081 15.9 0.2 1.3 1 0 0 1 1 1 1 Cyclin-dependent kinase inhibitor 3 (CDKN3) AAA PF00004.29 OQS06312.1 - 2.3e-45 154.3 0.0 7.9e-24 84.6 0.0 2.8 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 OQS06312.1 - 3.1e-13 49.3 0.2 4.8e-07 29.5 0.0 2.9 3 0 0 3 3 3 2 AAA+ lid domain AAA_16 PF13191.6 OQS06312.1 - 1.2e-06 29.0 8.0 0.015 15.7 0.0 4.2 2 2 2 5 5 5 2 AAA ATPase domain IstB_IS21 PF01695.17 OQS06312.1 - 2.4e-05 24.2 0.1 0.041 13.6 0.0 2.6 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_22 PF13401.6 OQS06312.1 - 3.2e-05 24.2 1.0 0.7 10.2 0.0 3.9 2 2 1 3 3 3 2 AAA domain AAA_33 PF13671.6 OQS06312.1 - 4.3e-05 23.7 0.0 0.092 12.9 0.0 2.8 2 1 0 2 2 2 2 AAA domain NACHT PF05729.12 OQS06312.1 - 5.2e-05 23.2 2.9 1.1 9.1 0.0 4.2 2 2 2 4 4 4 1 NACHT domain ABC_tran PF00005.27 OQS06312.1 - 0.00012 22.6 0.0 0.55 10.7 0.0 2.8 2 1 0 2 2 2 2 ABC transporter AAA_29 PF13555.6 OQS06312.1 - 0.00013 21.7 0.6 0.024 14.4 0.0 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain RNA_helicase PF00910.22 OQS06312.1 - 0.00013 22.3 0.0 0.53 10.7 0.0 3.0 3 0 0 3 3 2 2 RNA helicase Bac_DnaA PF00308.18 OQS06312.1 - 0.00046 20.1 0.0 0.016 15.0 0.0 2.7 2 1 0 2 2 2 1 Bacterial dnaA protein DUF815 PF05673.13 OQS06312.1 - 0.00053 19.2 0.0 0.047 12.9 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF815) Hpr_kinase_C PF07475.12 OQS06312.1 - 0.0029 17.2 1.1 0.37 10.3 0.2 2.4 2 0 0 2 2 2 1 HPr Serine kinase C-terminal domain AAA_18 PF13238.6 OQS06312.1 - 0.0038 17.8 0.0 2.3 8.8 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.14 OQS06312.1 - 0.0041 17.1 0.1 2.2 8.3 0.0 3.2 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) AAA_24 PF13479.6 OQS06312.1 - 0.012 15.3 0.2 3 7.5 0.0 2.7 3 0 0 3 3 3 0 AAA domain KAP_NTPase PF07693.14 OQS06312.1 - 0.023 13.9 0.0 0.45 9.7 0.0 2.2 2 0 0 2 2 2 0 KAP family P-loop domain Zeta_toxin PF06414.12 OQS06312.1 - 0.038 13.3 0.0 1.1 8.6 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin Sigma54_activat PF00158.26 OQS06312.1 - 0.05 13.3 0.0 12 5.5 0.0 2.8 2 0 0 2 2 2 0 Sigma-54 interaction domain DUF4556 PF15094.6 OQS06312.1 - 0.054 12.7 0.0 0.098 11.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4556) AAA_7 PF12775.7 OQS06312.1 - 0.095 12.2 0.0 6.7 6.2 0.0 2.6 2 0 0 2 2 2 0 P-loop containing dynein motor region Thymidylate_kin PF02223.17 OQS06312.1 - 0.15 11.7 0.0 0.39 10.4 0.0 1.7 1 0 0 1 1 1 0 Thymidylate kinase AAA_28 PF13521.6 OQS06312.1 - 0.15 12.3 0.0 20 5.4 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 OQS06312.1 - 0.26 10.8 0.9 31 4.0 0.1 2.9 2 1 0 2 2 2 0 AAA domain zf-NADH-PPase PF09297.11 OQS06313.1 - 0.00074 19.1 8.4 0.015 14.9 0.6 3.2 3 0 0 3 3 3 2 NADH pyrophosphatase zinc ribbon domain DZR PF12773.7 OQS06313.1 - 0.0014 18.6 15.9 0.0084 16.1 16.0 2.2 1 1 0 1 1 1 1 Double zinc ribbon zinc_ribbon_2 PF13240.6 OQS06313.1 - 0.0025 17.4 14.7 0.22 11.3 6.3 2.8 2 1 0 2 2 2 2 zinc-ribbon domain NOB1_Zn_bind PF08772.11 OQS06313.1 - 0.0075 16.4 1.1 0.0075 16.4 1.1 2.5 1 1 1 2 2 2 1 Nin one binding (NOB1) Zn-ribbon like zf-ribbon_3 PF13248.6 OQS06313.1 - 0.18 11.2 11.0 0.22 11.0 0.4 3.0 2 0 0 2 2 2 0 zinc-ribbon domain UPF0547 PF10571.9 OQS06313.1 - 0.2 11.7 14.2 0.4 10.8 5.6 2.7 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 PolC_DP2 PF03833.13 OQS06313.1 - 0.97 7.2 10.4 1.2 6.9 10.4 1.1 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 zinc_ribbon_15 PF17032.5 OQS06313.1 - 1.2 9.9 16.0 0.92 10.3 6.8 2.7 2 0 0 2 2 2 0 zinc-ribbon family AT_hook PF02178.19 OQS06314.1 - 0.0036 17.0 19.9 0.08 12.9 2.2 3.6 3 0 0 3 3 3 2 AT hook motif Ribul_P_3_epim PF00834.19 OQS06317.1 - 2.7e-68 229.3 0.1 3.1e-68 229.1 0.1 1.0 1 0 0 1 1 1 1 Ribulose-phosphate 3 epimerase family OMPdecase PF00215.24 OQS06317.1 - 0.0061 16.2 0.0 0.023 14.3 0.0 1.7 1 1 0 2 2 2 1 Orotidine 5'-phosphate decarboxylase / HUMPS family ThiG PF05690.14 OQS06317.1 - 0.042 13.1 0.2 0.062 12.6 0.2 1.2 1 0 0 1 1 1 0 Thiazole biosynthesis protein ThiG PG_binding_3 PF09374.10 OQS06317.1 - 0.057 13.7 0.0 0.15 12.3 0.0 1.7 2 0 0 2 2 2 0 Predicted Peptidoglycan domain QRPTase_C PF01729.19 OQS06317.1 - 0.12 12.2 0.0 1.2 8.9 0.0 2.2 2 0 0 2 2 2 0 Quinolinate phosphoribosyl transferase, C-terminal domain DUF2058 PF09831.9 OQS06319.1 - 0.021 15.0 0.2 0.021 15.0 0.2 2.1 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2058) Chlorophyllase PF07224.11 OQS06320.1 - 0.052 12.6 0.0 0.062 12.3 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase PAS_6 PF08348.11 OQS06320.1 - 0.087 12.7 0.0 0.18 11.6 0.0 1.5 1 0 0 1 1 1 0 YheO-like PAS domain MRP-S33 PF08293.11 OQS06321.1 - 6.1e-11 42.4 0.5 1.3e-10 41.4 0.5 1.5 1 1 0 1 1 1 1 Mitochondrial ribosomal subunit S27 MEDS PF14417.6 OQS06322.1 - 0.2 11.5 0.0 1.6 8.5 0.0 2.0 2 0 0 2 2 2 0 MEDS: MEthanogen/methylotroph, DcmR Sensory domain AP_endonuc_2 PF01261.24 OQS06323.1 - 1.3e-05 24.8 0.2 3.9e-05 23.2 0.2 1.7 1 1 0 1 1 1 1 Xylose isomerase-like TIM barrel Pkinase PF00069.25 OQS06325.1 - 2.9e-15 56.3 0.9 6.2e-15 55.3 0.9 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQS06325.1 - 1.6e-11 44.0 0.4 2.3e-11 43.5 0.4 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase HAD_2 PF13419.6 OQS06325.1 - 0.00037 20.6 1.2 0.0024 18.0 0.1 2.2 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase CYTL1 PF15153.6 OQS06325.1 - 0.13 12.2 0.0 0.27 11.2 0.0 1.5 1 0 0 1 1 1 0 Cytokine-like protein 1 zf-RING_2 PF13639.6 OQS06327.1 - 1.9e-11 44.1 7.7 3.8e-11 43.1 7.7 1.6 1 0 0 1 1 1 1 Ring finger domain PX PF00787.24 OQS06327.1 - 1.1e-09 38.2 0.4 2.6e-09 37.1 0.2 1.7 1 1 0 1 1 1 1 PX domain zf-rbx1 PF12678.7 OQS06327.1 - 5.8e-09 36.1 6.2 1.2e-08 35.0 6.2 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 OQS06327.1 - 5.4e-08 32.6 4.1 1.3e-07 31.3 4.1 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 OQS06327.1 - 1.2e-07 31.4 1.0 3.5e-07 29.8 1.0 1.8 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4 PF00097.25 OQS06327.1 - 5.8e-07 29.3 3.5 1.4e-06 28.1 3.5 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OQS06327.1 - 7e-06 26.0 2.8 1.8e-05 24.6 2.8 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 OQS06327.1 - 8e-05 22.4 5.2 0.00016 21.5 5.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OQS06327.1 - 0.00037 20.4 5.7 0.0018 18.2 5.9 2.1 1 1 1 2 2 2 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 OQS06327.1 - 0.00065 19.7 5.1 0.0017 18.3 5.1 1.8 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger RINGv PF12906.7 OQS06327.1 - 0.0097 16.0 4.1 0.027 14.6 4.1 1.8 1 1 0 1 1 1 1 RING-variant domain Prok-RING_4 PF14447.6 OQS06327.1 - 0.017 14.9 6.0 0.038 13.8 5.3 1.9 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 zf-Nse PF11789.8 OQS06327.1 - 0.028 14.3 1.4 0.1 12.5 1.4 1.9 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit FANCL_C PF11793.8 OQS06327.1 - 0.029 14.5 7.8 0.065 13.4 6.8 2.2 2 1 0 2 2 1 0 FANCL C-terminal domain zf-C3H2C3 PF17122.5 OQS06327.1 - 0.045 13.8 3.0 0.21 11.6 3.1 2.1 2 1 0 2 2 2 0 Zinc-finger Zf_RING PF16744.5 OQS06327.1 - 0.27 11.4 4.1 0.72 10.0 4.1 1.7 1 0 0 1 1 1 0 KIAA1045 RING finger Zn_ribbon_17 PF17120.5 OQS06327.1 - 1.9 8.1 8.6 4.2 7.1 8.6 1.6 1 1 0 1 1 1 0 Zinc-ribbon, C4HC2 type DUF4200 PF13863.6 OQS06328.1 - 4.5e-21 75.4 33.3 1.3e-20 73.9 25.8 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF4200) DUF2935 PF11155.8 OQS06328.1 - 0.02 15.2 1.0 0.12 12.7 1.0 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF2935) DUF1664 PF07889.12 OQS06328.1 - 0.093 12.8 10.9 0.11 12.5 1.8 2.8 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) DUF4407 PF14362.6 OQS06328.1 - 0.46 9.8 20.2 1.4 8.2 0.4 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) ACP_PD PF04336.12 OQS06328.1 - 0.47 10.9 5.3 7.1 7.1 0.3 2.8 2 1 1 3 3 3 0 Acyl carrier protein phosphodiesterase NAD_binding_5 PF07994.12 OQS06328.1 - 1.2 8.4 7.8 2 7.7 2.8 2.2 2 0 0 2 2 2 0 Myo-inositol-1-phosphate synthase COG2 PF06148.11 OQS06328.1 - 2.6 8.2 19.2 1.1 9.4 7.6 2.7 1 1 2 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 OmpH PF03938.14 OQS06328.1 - 2.6 8.4 31.3 0.26 11.6 1.3 3.2 1 1 2 3 3 3 0 Outer membrane protein (OmpH-like) Golgin_A5 PF09787.9 OQS06328.1 - 3.7 6.9 32.0 1.6 8.1 17.0 2.2 1 1 1 2 2 2 0 Golgin subfamily A member 5 JIP_LZII PF16471.5 OQS06328.1 - 4.6 7.5 20.9 2.1 8.5 3.7 3.6 2 1 1 3 3 3 0 JNK-interacting protein leucine zipper II FliD_N PF02465.18 OQS06328.1 - 7.1 7.4 11.3 1.1 10.0 2.1 3.2 1 1 2 3 3 3 0 Flagellar hook-associated protein 2 N-terminus Lectin_N PF03954.14 OQS06328.1 - 7.3 6.3 10.7 3.7 7.3 0.3 3.2 1 1 2 3 3 3 0 Hepatic lectin, N-terminal domain Fez1 PF06818.15 OQS06328.1 - 8.1 6.8 28.3 5 7.5 5.7 2.1 1 1 1 2 2 2 0 Fez1 HEPN_Toprim_N PF18871.1 OQS06328.1 - 9.8 6.0 15.9 4.7 7.1 9.1 2.2 1 1 1 2 2 2 0 HEPN/Toprim N-terminal domain 1 ABM PF03992.16 OQS06329.1 - 2.5e-10 40.3 0.0 2.9e-10 40.1 0.0 1.1 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase DUF1330 PF07045.11 OQS06329.1 - 0.0044 17.3 0.0 0.0064 16.8 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1330) Dehydratase_hem PF13816.6 OQS06329.1 - 0.022 14.1 0.0 0.028 13.8 0.0 1.1 1 0 0 1 1 1 0 Haem-containing dehydratase Gasdermin PF04598.12 OQS06329.1 - 0.068 12.6 0.1 0.082 12.3 0.1 1.1 1 0 0 1 1 1 0 Gasdermin pore forming domain Dabb PF07876.12 OQS06329.1 - 0.095 13.3 0.0 0.12 13.0 0.0 1.1 1 0 0 1 1 1 0 Stress responsive A/B Barrel Domain Mon1 PF03164.14 OQS06330.1 - 7.1e-56 190.0 1.0 9.4e-56 189.6 1.0 1.0 1 0 0 1 1 1 1 Trafficking protein Mon1 YbjQ_1 PF01906.17 OQS06331.1 - 7.2e-06 26.6 0.0 3.3 8.4 0.0 4.2 4 0 0 4 4 4 3 Putative heavy-metal-binding Cluap1 PF10234.9 OQS06332.1 - 5e-98 327.8 10.8 8.2e-98 327.1 10.8 1.3 1 0 0 1 1 1 1 Clusterin-associated protein-1 Lebercilin PF15619.6 OQS06332.1 - 0.0086 15.8 19.0 0.0086 15.8 19.0 1.8 2 0 0 2 2 2 1 Ciliary protein causing Leber congenital amaurosis disease DUF3958 PF13125.6 OQS06332.1 - 0.022 15.0 1.8 0.022 15.0 1.8 3.6 1 1 2 3 3 3 0 Protein of unknown function (DUF3958) Prominin PF05478.11 OQS06332.1 - 0.39 8.6 7.5 0.12 10.3 4.1 1.6 1 1 1 2 2 2 0 Prominin DivIC PF04977.15 OQS06332.1 - 0.43 10.4 11.2 0.13 12.1 1.9 2.9 2 0 0 2 2 2 0 Septum formation initiator DUF1664 PF07889.12 OQS06332.1 - 1.4 8.9 6.7 1 9.4 2.3 2.2 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) BLOC1_2 PF10046.9 OQS06332.1 - 1.9 8.8 10.7 1.7 9.0 3.1 3.3 2 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 SPATA3 PF15662.5 OQS06332.1 - 9.4 6.8 10.4 22 5.6 10.4 1.7 1 0 0 1 1 1 0 Spermatogenesis-associated protein 3 family MatE PF01554.18 OQS06333.1 - 3.2e-48 163.4 38.0 9e-25 87.2 12.3 3.3 2 1 0 2 2 2 2 MatE Methyltransf_PK PF05891.12 OQS06334.1 - 2.5e-68 229.9 0.0 6.2e-68 228.6 0.0 1.6 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Kelch_4 PF13418.6 OQS06334.1 - 8.1e-20 70.6 9.0 9.5e-09 35.1 0.1 6.0 6 0 0 6 6 6 3 Galactose oxidase, central domain Kelch_5 PF13854.6 OQS06334.1 - 4.6e-16 58.4 3.5 1.5e-05 24.8 0.0 5.4 6 0 0 6 6 6 3 Kelch motif Kelch_6 PF13964.6 OQS06334.1 - 1e-11 44.6 2.4 6.2e-06 26.3 0.0 5.4 5 0 0 5 5 5 1 Kelch motif Kelch_3 PF13415.6 OQS06334.1 - 8.7e-10 38.6 0.9 0.00011 22.4 0.0 5.1 5 0 0 5 5 5 1 Galactose oxidase, central domain Kelch_1 PF01344.25 OQS06334.1 - 1.1e-08 34.5 2.0 0.072 12.7 0.0 4.8 5 0 0 5 5 5 3 Kelch motif Kelch_2 PF07646.15 OQS06334.1 - 3e-07 30.2 4.0 0.072 13.1 0.0 5.7 6 0 0 6 6 6 2 Kelch motif Methyltransf_25 PF13649.6 OQS06334.1 - 1.5e-06 28.8 0.0 5.2e-06 27.1 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OQS06334.1 - 2.8e-06 27.9 0.0 6.5e-06 26.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OQS06334.1 - 2.5e-05 25.0 0.0 7.1e-05 23.5 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.18 OQS06334.1 - 0.0061 15.9 0.0 0.011 15.0 0.0 1.4 1 0 0 1 1 1 1 O-methyltransferase domain Lyase_1 PF00206.20 OQS06334.1 - 0.032 13.6 4.6 0.054 12.9 4.6 1.2 1 0 0 1 1 1 0 Lyase Occludin_ELL PF07303.13 OQS06334.1 - 0.37 11.5 6.4 0.63 10.8 0.8 2.6 2 0 0 2 2 2 0 Occludin homology domain IFT57 PF10498.9 OQS06334.1 - 0.79 8.6 12.4 0.091 11.7 4.4 2.1 1 1 1 2 2 2 0 Intra-flagellar transport protein 57 HALZ PF02183.18 OQS06334.1 - 0.86 9.9 6.1 4.5 7.6 0.2 2.9 2 1 0 2 2 2 0 Homeobox associated leucine zipper TPR_MLP1_2 PF07926.12 OQS06334.1 - 0.91 9.6 13.8 1.5 8.9 4.8 2.3 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein PB1 PF00564.24 OQS06335.1 - 5.2e-07 29.5 0.0 1.8e-06 27.8 0.0 1.9 2 0 0 2 2 2 1 PB1 domain UBA_4 PF14555.6 OQS06335.1 - 0.033 14.0 0.2 0.094 12.5 0.0 1.8 2 0 0 2 2 2 0 UBA-like domain CUE PF02845.16 OQS06335.1 - 0.084 12.6 2.0 0.097 12.4 0.2 2.1 2 0 0 2 2 2 0 CUE domain EFG_IV PF03764.18 OQS06335.1 - 0.091 12.5 1.4 0.14 12.0 0.1 1.9 2 0 0 2 2 2 0 Elongation factor G, domain IV Phasin_2 PF09361.10 OQS06335.1 - 0.59 10.4 12.0 1 9.7 4.3 2.6 1 1 1 2 2 2 0 Phasin protein Ricin_B_lectin PF00652.22 OQS06336.1 - 1.1e-20 74.1 20.2 6.3e-11 42.6 5.1 4.0 4 1 0 4 4 4 2 Ricin-type beta-trefoil lectin domain Trypsin_2 PF13365.6 OQS06336.1 - 2e-12 48.3 0.0 3.6e-12 47.4 0.0 1.5 1 0 0 1 1 1 1 Trypsin-like peptidase domain RicinB_lectin_2 PF14200.6 OQS06336.1 - 6.2e-11 42.9 8.6 4.5e-05 24.1 1.7 3.8 3 1 1 4 4 4 3 Ricin-type beta-trefoil lectin domain-like CDtoxinA PF03498.14 OQS06336.1 - 3.6e-05 23.4 6.5 0.005 16.4 0.5 3.5 1 1 2 3 3 3 2 Cytolethal distending toxin A/C domain FAIM1 PF06905.13 OQS06336.1 - 0.097 12.4 0.2 7.7 6.2 0.0 2.2 2 0 0 2 2 2 0 Fas apoptotic inhibitory molecule (FAIM1) ATF7IP_BD PF16788.5 OQS06336.1 - 5.8 7.0 6.7 12 5.9 2.2 2.4 2 0 0 2 2 2 0 ATF-interacting protein binding domain Voltage_CLC PF00654.20 OQS06337.1 - 7.2e-80 268.9 24.4 7.2e-80 268.9 24.4 1.9 2 0 0 2 2 2 1 Voltage gated chloride channel CBS PF00571.28 OQS06337.1 - 1.4e-06 28.6 0.0 6.3e-05 23.3 0.0 2.7 2 0 0 2 2 2 1 CBS domain Cupin_8 PF13621.6 OQS06338.1 - 2.4e-30 106.1 0.5 3.3e-30 105.7 0.5 1.1 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.12 OQS06338.1 - 1.5e-06 27.9 0.2 6e-06 25.9 0.1 1.8 1 1 0 1 1 1 1 Cupin superfamily protein JmjC PF02373.22 OQS06338.1 - 0.002 18.5 0.0 0.004 17.6 0.0 1.5 1 0 0 1 1 1 1 JmjC domain, hydroxylase Mob1_phocein PF03637.17 OQS06339.1 - 1.1e-11 45.0 4.5 1.1e-08 35.3 3.0 2.2 1 1 0 2 2 2 2 Mob1/phocein family Y_phosphatase2 PF03162.13 OQS06340.1 - 5.9e-55 185.3 0.0 6.4e-55 185.2 0.0 1.0 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.6 OQS06340.1 - 1.9e-05 24.7 0.0 4.5e-05 23.5 0.0 1.6 1 1 0 1 1 1 1 Tyrosine phosphatase family DSPc PF00782.20 OQS06340.1 - 0.00033 20.5 0.0 0.00044 20.1 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 OQS06340.1 - 0.0017 18.0 0.0 0.002 17.7 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Lactamase_B_3 PF13483.6 OQS06340.1 - 0.073 13.0 0.0 0.092 12.6 0.0 1.1 1 0 0 1 1 1 0 Beta-lactamase superfamily domain PB1 PF00564.24 OQS06341.1 - 0.00021 21.1 0.0 0.00044 20.1 0.0 1.6 1 0 0 1 1 1 1 PB1 domain CUE PF02845.16 OQS06341.1 - 0.027 14.2 0.0 0.064 13.0 0.0 1.5 1 0 0 1 1 1 0 CUE domain cwf18 PF08315.12 OQS06342.1 - 4e-17 63.2 3.2 4e-17 63.2 3.2 3.0 2 1 1 3 3 3 2 cwf18 pre-mRNA splicing factor CNOT1_HEAT PF16418.5 OQS06342.1 - 0.0042 17.2 1.8 0.0045 17.1 1.1 1.4 2 0 0 2 2 2 1 CCR4-NOT transcription complex subunit 1 HEAT repeat DUF688 PF05097.12 OQS06342.1 - 0.0072 15.5 5.1 0.0088 15.3 5.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF688) Sporozoite_P67 PF05642.11 OQS06342.1 - 0.8 7.7 5.9 0.78 7.7 5.9 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen NOA36 PF06524.12 OQS06342.1 - 1.2 8.4 7.2 1.9 7.7 7.2 1.5 1 0 0 1 1 1 0 NOA36 protein Myc_N PF01056.18 OQS06342.1 - 3 7.6 12.1 3.7 7.4 12.1 1.2 1 0 0 1 1 1 0 Myc amino-terminal region PBP_sp32 PF07222.12 OQS06342.1 - 8.5 5.8 18.5 11 5.4 18.5 1.2 1 1 0 1 1 1 0 Proacrosin binding protein sp32 HU-CCDC81_euk_2 PF18289.1 OQS06343.1 - 1.1e-13 51.1 0.1 3.3e-13 49.6 0.0 1.9 2 0 0 2 2 2 1 CCDC81 eukaryotic HU domain 2 HU-CCDC81_euk_1 PF14908.6 OQS06343.1 - 2.5e-08 33.9 0.0 3.1e-07 30.4 0.0 2.5 2 0 0 2 2 2 1 CCDC81 eukaryotic HU domain 1 DUF1764 PF08576.10 OQS06343.1 - 7.4 7.5 10.4 2.4 9.1 4.0 2.5 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF1764) Syja_N PF02383.18 OQS06344.1 - 1.7e-75 254.3 0.3 3.2e-75 253.4 0.3 1.5 1 0 0 1 1 1 1 SacI homology domain WYL PF13280.6 OQS06344.1 - 0.03 14.4 0.2 0.16 12.0 0.1 2.1 2 0 0 2 2 2 0 WYL domain AAA_22 PF13401.6 OQS06345.1 - 7.2e-10 39.3 0.0 2e-09 37.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain NACHT PF05729.12 OQS06345.1 - 7e-06 26.1 0.1 2.8e-05 24.1 0.0 2.1 2 0 0 2 2 2 1 NACHT domain AAA_16 PF13191.6 OQS06345.1 - 9.5e-06 26.1 0.0 2.5e-05 24.7 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain NB-ARC PF00931.22 OQS06345.1 - 0.0013 18.0 0.0 0.0046 16.2 0.0 1.9 1 1 0 1 1 1 1 NB-ARC domain AAA PF00004.29 OQS06345.1 - 0.0024 18.3 0.0 0.0052 17.2 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.17 OQS06345.1 - 0.0039 17.0 0.0 0.015 15.1 0.0 2.0 1 0 0 1 1 1 1 IstB-like ATP binding protein NTPase_1 PF03266.15 OQS06345.1 - 0.0041 17.0 0.0 0.01 15.8 0.0 1.7 1 1 0 1 1 1 1 NTPase FHA PF00498.26 OQS06345.1 - 0.017 15.5 0.1 0.059 13.7 0.1 2.0 2 0 0 2 2 2 0 FHA domain RNA_helicase PF00910.22 OQS06345.1 - 0.096 13.1 0.0 1.4 9.3 0.0 2.6 2 0 0 2 2 2 0 RNA helicase AAA_24 PF13479.6 OQS06345.1 - 0.097 12.4 0.0 0.16 11.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 OQS06345.1 - 0.1 13.1 0.0 0.21 12.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain MFS_1 PF07690.16 OQS06346.1 - 8.5e-58 195.9 132.6 4.3e-19 68.6 20.2 5.7 4 1 1 6 6 6 4 Major Facilitator Superfamily DUF5592 PF17332.2 OQS06346.1 - 7.3 7.2 23.0 5.1 7.7 1.3 5.5 4 0 0 4 4 4 0 Family of unknown function (DUF5592) DUF3270 PF11674.8 OQS06346.1 - 9.2 6.5 25.2 1.2 9.3 1.0 6.2 5 0 0 5 5 5 0 Protein of unknown function (DUF3270) PX PF00787.24 OQS06347.1 - 0.00035 20.5 0.0 0.00047 20.1 0.0 1.2 1 0 0 1 1 1 1 PX domain Met_gamma_lyase PF06838.11 OQS06347.1 - 0.018 13.6 0.0 0.032 12.8 0.0 1.4 1 0 0 1 1 1 0 Methionine gamma-lyase MFS_1 PF07690.16 OQS06348.1 - 3.1e-32 111.9 46.9 3.6e-17 62.3 20.7 3.1 3 2 0 3 3 3 2 Major Facilitator Superfamily ATP19 PF11022.8 OQS06348.1 - 0.11 12.9 0.5 19 5.7 0.0 3.1 2 0 0 2 2 2 0 ATP synthase subunit K Prismane PF03063.20 OQS06352.1 - 2.1e-129 432.6 0.0 2.7e-129 432.2 0.0 1.1 1 0 0 1 1 1 1 Prismane/CO dehydrogenase family FAD_binding_1 PF00667.20 OQS06352.1 - 8.6e-36 123.6 0.0 1.4e-35 122.9 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 OQS06352.1 - 1.4e-28 99.9 0.0 2.6e-28 99.0 0.0 1.5 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.21 OQS06352.1 - 1.9e-07 31.7 0.0 7.2e-07 29.8 0.0 2.0 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Flavodoxin_5 PF12724.7 OQS06352.1 - 2.2e-05 24.7 0.0 4.5e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 Flavodoxin domain NAD_binding_6 PF08030.12 OQS06352.1 - 0.19 11.8 0.0 0.97 9.5 0.0 2.2 3 1 0 3 3 3 0 Ferric reductase NAD binding domain FAD_binding_3 PF01494.19 OQS06353.1 - 2.4e-08 33.6 0.0 1e-07 31.5 0.0 1.8 1 1 0 1 1 1 1 FAD binding domain SE PF08491.10 OQS06353.1 - 0.088 11.8 0.0 1.2 8.1 0.0 2.0 2 0 0 2 2 2 0 Squalene epoxidase Vps35 PF03635.17 OQS06354.1 - 1.4e-09 37.0 8.0 5.7e-05 21.8 0.0 2.1 2 0 0 2 2 2 2 Vacuolar protein sorting-associated protein 35 Orthopox_A49R PF06489.11 OQS06354.1 - 0.035 14.4 1.6 0.11 12.7 0.3 2.2 2 0 0 2 2 2 0 Orthopoxvirus A49R protein Band_7 PF01145.25 OQS06356.1 - 5.6e-22 78.6 4.1 5.6e-22 78.6 4.1 1.7 1 1 0 2 2 2 1 SPFH domain / Band 7 family Myb_DNA-bind_3 PF12776.7 OQS06357.1 - 1.9e-18 67.2 0.6 4.7e-18 66.0 0.6 1.7 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain DUF573 PF04504.14 OQS06357.1 - 0.023 15.3 0.3 0.063 13.9 0.2 1.8 2 0 0 2 2 2 0 Protein of unknown function, DUF573 Myb_DNA-bind_4 PF13837.6 OQS06357.1 - 0.045 14.1 0.4 0.24 11.8 0.1 2.4 3 1 0 3 3 3 0 Myb/SANT-like DNA-binding domain Acetyltransf_1 PF00583.25 OQS06358.1 - 1.6e-13 50.9 0.0 2.1e-13 50.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 OQS06358.1 - 1.3e-09 38.0 0.0 1.7e-09 37.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 OQS06358.1 - 7.6e-09 35.9 0.0 1.3e-08 35.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 OQS06358.1 - 1.8e-07 31.0 0.0 2.8e-07 30.4 0.0 1.2 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_4 PF13420.7 OQS06358.1 - 0.0032 17.6 0.1 0.0044 17.2 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 OQS06358.1 - 0.0034 17.5 0.3 0.015 15.4 0.3 2.0 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain SLD5_C PF16922.5 OQS06359.1 - 2.7e-14 53.1 0.0 4.5e-14 52.4 0.0 1.4 1 0 0 1 1 1 1 DNA replication complex GINS protein SLD5 C-terminus Sld5 PF05916.11 OQS06359.1 - 5.5e-06 26.8 3.5 1.3e-05 25.6 3.5 1.7 1 1 0 1 1 1 1 GINS complex protein MtlR PF05068.12 OQS06359.1 - 0.011 15.8 2.3 0.018 15.1 2.3 1.3 1 0 0 1 1 1 0 Mannitol repressor GSH_synth_ATP PF03917.17 OQS06359.1 - 0.027 13.3 0.7 0.031 13.0 0.7 1.1 1 0 0 1 1 1 0 Eukaryotic glutathione synthase, ATP binding domain Sigma54_activ_2 PF14532.6 OQS06359.1 - 0.065 13.3 1.1 0.58 10.3 1.1 2.1 1 1 0 1 1 1 0 Sigma-54 interaction domain Flu_PB1 PF00602.17 OQS06359.1 - 0.087 10.9 1.2 0.11 10.6 1.2 1.1 1 0 0 1 1 1 0 Influenza RNA-dependent RNA polymerase subunit PB1 MCM_N PF14551.6 OQS06359.1 - 0.11 13.1 5.6 0.23 12.0 2.4 2.1 1 1 1 2 2 2 0 MCM N-terminal domain DUF4558 PF15104.6 OQS06359.1 - 0.24 11.5 5.1 1.8 8.7 1.0 3.1 3 1 1 4 4 4 0 Domain of unknown function (DUF4558) Sulfate_transp PF00916.20 OQS06360.1 - 4e-24 85.1 24.2 4e-24 85.1 24.2 1.4 2 0 0 2 2 2 1 Sulfate permease family STAS PF01740.21 OQS06360.1 - 9.4e-10 38.1 0.0 2.2e-09 37.0 0.0 1.6 1 0 0 1 1 1 1 STAS domain cNMP_binding PF00027.29 OQS06360.1 - 1.4e-07 31.4 0.0 3.6e-07 30.2 0.0 1.6 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Ank_2 PF12796.7 OQS06362.1 - 3.9e-21 75.4 4.5 6.2e-11 42.7 0.5 3.1 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OQS06362.1 - 9e-14 50.2 2.4 0.00099 19.4 0.1 5.0 5 0 0 5 5 5 3 Ankyrin repeat Ank_4 PF13637.6 OQS06362.1 - 1.2e-12 48.1 0.2 2.6e-06 27.9 0.1 3.9 4 0 0 4 4 4 2 Ankyrin repeats (many copies) Ank PF00023.30 OQS06362.1 - 1.1e-11 44.6 0.8 0.00049 20.4 0.1 4.2 4 1 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.6 OQS06362.1 - 3.6e-10 39.9 1.2 2e-06 28.0 0.2 4.7 3 2 2 5 5 5 2 Ankyrin repeats (many copies) Mago_nashi PF02792.14 OQS06362.1 - 0.056 13.6 0.2 38 4.4 0.0 3.1 3 0 0 3 3 3 0 Mago nashi protein TPR_12 PF13424.6 OQS06365.1 - 0.053 13.8 0.5 18 5.7 0.0 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF3545 PF12065.8 OQS06366.1 - 0.07 13.2 0.1 0.13 12.3 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3545) Pkinase_Tyr PF07714.17 OQS06367.1 - 1.9e-54 184.7 0.0 3.3e-54 183.9 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OQS06367.1 - 4.1e-52 177.2 0.0 5.9e-52 176.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 OQS06367.1 - 0.00057 19.3 0.0 0.00081 18.8 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 OQS06367.1 - 0.0033 16.3 0.0 0.0051 15.6 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 OQS06367.1 - 0.042 13.2 0.0 0.068 12.5 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF3139 PF11337.8 OQS06367.1 - 0.05 14.3 0.2 0.15 12.8 0.2 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3139) AP_endonuc_2 PF01261.24 OQS06367.1 - 0.19 11.1 0.0 2.3 7.6 0.0 2.3 2 1 0 3 3 3 0 Xylose isomerase-like TIM barrel DUF3015 PF11220.8 OQS06367.1 - 1.4 8.8 8.6 4 7.3 0.4 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3015) Pkinase_Tyr PF07714.17 OQS06368.1 - 5.6e-53 179.9 0.1 9.5e-29 100.5 0.0 3.2 2 1 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 OQS06368.1 - 2.4e-51 174.6 0.1 4.2e-26 91.9 0.0 2.7 2 1 0 2 2 2 2 Protein kinase domain Kinase-like PF14531.6 OQS06368.1 - 6.7e-07 28.9 0.1 0.04 13.2 0.0 2.5 2 0 0 2 2 2 2 Kinase-like Gram_pos_anchor PF00746.21 OQS06368.1 - 0.0029 17.5 0.2 0.92 9.5 0.2 2.5 2 0 0 2 2 2 2 LPXTG cell wall anchor motif LapA_dom PF06305.11 OQS06368.1 - 0.0032 17.2 0.0 4.4 7.2 0.0 2.6 2 0 0 2 2 2 2 Lipopolysaccharide assembly protein A domain EphA2_TM PF14575.6 OQS06368.1 - 0.0043 17.9 0.0 4.4 8.3 0.0 2.5 2 0 0 2 2 2 2 Ephrin type-A receptor 2 transmembrane domain Abhydrolase_9_N PF15420.6 OQS06368.1 - 0.05 13.6 0.1 0.23 11.4 0.0 2.1 2 0 0 2 2 2 0 Alpha/beta-hydrolase family N-terminus DUF202 PF02656.15 OQS06368.1 - 0.12 12.8 0.4 7 7.2 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF202) TPR_12 PF13424.6 OQS06369.1 - 3.7e-06 27.1 0.8 0.013 15.7 0.2 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_10 PF13374.6 OQS06369.1 - 0.22 11.4 0.4 70 3.5 0.0 3.4 4 0 0 4 4 4 0 Tetratricopeptide repeat Pkinase_Tyr PF07714.17 OQS06374.1 - 1.1e-48 165.8 0.0 1.5e-48 165.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OQS06374.1 - 6.4e-46 156.9 0.0 1e-45 156.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 OQS06374.1 - 5.4e-06 25.9 0.2 8.7e-06 25.2 0.2 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 OQS06374.1 - 0.0033 16.4 0.2 0.0058 15.6 0.1 1.4 1 1 0 1 1 1 1 Haspin like kinase domain TMEM51 PF15345.6 OQS06374.1 - 0.0046 16.8 0.0 0.0097 15.8 0.0 1.4 1 0 0 1 1 1 1 Transmembrane protein 51 Kinase-like PF14531.6 OQS06374.1 - 0.0057 16.0 0.0 0.01 15.2 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Orf78 PF06024.12 OQS06374.1 - 0.063 13.6 0.0 0.14 12.4 0.0 1.5 1 0 0 1 1 1 0 Orf78 (ac78) DUF4366 PF14283.6 OQS06374.1 - 0.12 12.4 0.0 0.27 11.3 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) Podoplanin PF05808.11 OQS06374.1 - 0.14 12.2 5.6 0.34 11.0 5.6 1.6 1 0 0 1 1 1 0 Podoplanin SAP130_C PF16014.5 OQS06374.1 - 2.4 7.2 13.3 4 6.4 13.3 1.3 1 0 0 1 1 1 0 Histone deacetylase complex subunit SAP130 C-terminus PI3_PI4_kinase PF00454.27 OQS06375.1 - 1.3e-46 159.4 0.1 1.6e-44 152.7 0.1 2.5 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.20 OQS06375.1 - 1.9e-38 131.8 2.3 4e-38 130.7 2.3 1.5 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PH PF00169.29 OQS06375.1 - 3.6e-18 66.0 4.6 1.3e-11 44.9 1.2 2.6 2 0 0 2 2 2 2 PH domain PI3K_rbd PF00794.18 OQS06375.1 - 7e-05 22.9 0.3 0.0002 21.5 0.1 1.9 2 0 0 2 2 2 1 PI3-kinase family, ras-binding domain PI3K_C2 PF00792.24 OQS06375.1 - 0.00031 20.7 0.0 0.00081 19.3 0.0 1.7 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 DUF4135 PF13575.6 OQS06375.1 - 0.0016 17.9 0.0 0.0028 17.1 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4135) PH_4 PF15404.6 OQS06375.1 - 0.0057 16.5 0.4 0.017 14.9 0.2 1.8 2 0 0 2 2 2 1 Pleckstrin homology domain PH_11 PF15413.6 OQS06375.1 - 0.07 13.6 1.4 0.29 11.6 1.4 2.2 1 0 0 1 1 1 0 Pleckstrin homology domain Glycos_transf_1 PF00534.20 OQS06375.1 - 0.21 11.1 0.1 0.65 9.5 0.0 1.8 2 0 0 2 2 2 0 Glycosyl transferases group 1 NUDIX PF00293.28 OQS06376.1 - 1.4e-15 57.5 0.0 2.7e-15 56.5 0.0 1.5 1 0 0 1 1 1 1 NUDIX domain OTU PF02338.19 OQS06376.1 - 3.4e-07 30.8 0.0 2.4e-06 28.1 0.0 2.4 2 0 0 2 2 2 1 OTU-like cysteine protease FAM176 PF14851.6 OQS06376.1 - 3.6 7.3 6.6 0.21 11.3 0.4 2.1 2 1 0 2 2 2 0 FAM176 family MFS_1 PF07690.16 OQS06377.1 - 1.2e-92 310.6 204.9 5.6e-24 84.7 39.1 7.1 4 3 3 7 7 7 7 Major Facilitator Superfamily Sugar_tr PF00083.24 OQS06377.1 - 1e-27 97.1 90.4 2.6e-10 39.8 8.7 5.5 6 0 0 6 6 6 4 Sugar (and other) transporter NUC153 PF08159.12 OQS06378.1 - 2.4e-09 36.8 2.1 5.6e-09 35.6 2.1 1.7 1 0 0 1 1 1 1 NUC153 domain BBS2_Mid PF14783.6 OQS06378.1 - 1.4e-06 28.3 0.0 0.00078 19.4 0.0 3.2 3 0 0 3 3 3 2 Ciliary BBSome complex subunit 2, middle region WD40 PF00400.32 OQS06378.1 - 0.00021 22.0 0.5 15 6.6 0.0 5.6 5 0 0 5 5 5 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OQS06378.1 - 0.00022 21.5 0.1 0.012 15.9 0.0 3.7 4 1 1 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 OQS06378.1 - 0.0013 17.8 0.1 1.1 8.1 0.0 2.7 3 0 0 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Cytomega_UL84 PF06284.11 OQS06378.1 - 0.58 8.6 4.8 0.97 7.8 4.8 1.2 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein CDC45 PF02724.14 OQS06378.1 - 7.9 4.6 11.8 14 3.8 11.8 1.3 1 0 0 1 1 1 0 CDC45-like protein Carb_anhydrase PF00194.21 OQS06379.1 - 1.1e-17 64.5 0.0 2.8e-17 63.1 0.0 1.7 1 1 0 1 1 1 1 Eukaryotic-type carbonic anhydrase Lactamase_B PF00753.27 OQS06380.1 - 5.8e-17 62.3 0.1 4.3e-16 59.5 0.1 2.1 2 1 0 2 2 2 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 OQS06380.1 - 5.9e-05 22.7 0.0 7.4e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_6 PF16661.5 OQS06380.1 - 0.046 13.1 0.0 0.08 12.4 0.0 1.4 1 0 0 1 1 1 0 Metallo-beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 OQS06380.1 - 0.13 12.2 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 Beta-lactamase superfamily domain C2 PF00168.30 OQS06381.1 - 6.9e-06 26.3 0.0 1.7e-05 25.0 0.0 1.7 1 1 1 2 2 2 1 C2 domain AA_permease PF00324.21 OQS06382.1 - 1.4e-68 231.6 34.0 1.8e-68 231.3 34.0 1.1 1 0 0 1 1 1 1 Amino acid permease SLC12 PF03522.15 OQS06382.1 - 1.5e-16 60.4 1.7 2e-08 33.7 0.0 3.1 2 1 1 3 3 3 3 Solute carrier family 12 Sulfotransfer_1 PF00685.27 OQS06382.1 - 7.8e-08 32.1 1.9 1.4e-06 28.0 1.9 2.3 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 OQS06382.1 - 2.8e-06 27.9 1.1 0.00015 22.2 0.7 2.3 2 0 0 2 2 2 1 Sulfotransferase family HAD PF12710.7 OQS06382.1 - 0.024 15.1 0.1 0.11 12.9 0.0 2.0 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase DUF1450 PF07293.11 OQS06382.1 - 0.19 11.6 0.0 0.39 10.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1450) dCMP_cyt_deam_1 PF00383.23 OQS06383.1 - 2.4e-20 72.3 1.0 4.9e-20 71.3 1.0 1.6 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 OQS06383.1 - 1.6e-17 63.5 0.1 1.4e-15 57.3 0.1 2.2 1 1 0 1 1 1 1 MafB19-like deaminase Ank_5 PF13857.6 OQS06383.1 - 0.064 13.6 0.2 5.6 7.4 0.0 2.7 3 0 0 3 3 3 0 Ankyrin repeats (many copies) Thymidylat_synt PF00303.19 OQS06384.1 - 2.9e-118 393.8 0.0 3.6e-118 393.5 0.0 1.1 1 0 0 1 1 1 1 Thymidylate synthase DHFR_1 PF00186.19 OQS06384.1 - 4.7e-43 146.7 0.0 9.5e-43 145.7 0.0 1.5 2 0 0 2 2 2 1 Dihydrofolate reductase PX PF00787.24 OQS06385.1 - 3e-07 30.4 0.3 3e-07 30.4 0.3 2.3 3 0 0 3 3 3 1 PX domain WH2 PF02205.20 OQS06385.1 - 4.6e-06 26.3 0.4 1e-05 25.2 0.4 1.6 1 0 0 1 1 1 1 WH2 motif Lebercilin PF15619.6 OQS06386.1 - 0.77 9.4 29.8 0.94 9.1 0.7 2.2 1 1 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease Polysacc_synt PF01943.17 OQS06386.1 - 1.7 8.0 17.6 15 4.9 17.6 2.0 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein GIDA_assoc PF13932.6 OQS06386.1 - 2.5 8.3 13.2 4.5 7.4 13.2 1.4 1 0 0 1 1 1 0 GidA associated domain DUF812 PF05667.11 OQS06386.1 - 3.5 6.4 27.4 4.7 6.0 27.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) Fib_alpha PF08702.10 OQS06386.1 - 4.6 7.4 13.6 3.4 7.8 5.0 2.3 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family DUF948 PF06103.11 OQS06386.1 - 5.2 7.4 10.3 11 6.4 2.5 3.0 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Sec34 PF04136.15 OQS06386.1 - 5.6 6.8 11.1 0.58 10.0 2.4 2.3 2 0 0 2 2 2 0 Sec34-like family Fez1 PF06818.15 OQS06386.1 - 8.1 6.8 25.8 24 5.3 12.1 2.2 1 1 1 2 2 2 0 Fez1 FtsJ PF01728.19 OQS06387.1 - 1.3e-38 132.8 0.0 2.7e-38 131.8 0.0 1.5 1 0 0 1 1 1 1 FtsJ-like methyltransferase Ank_2 PF12796.7 OQS06387.1 - 1.5e-11 44.7 2.0 0.00018 22.0 0.1 3.1 1 1 2 3 3 3 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OQS06387.1 - 7e-09 35.8 2.6 0.003 17.8 0.0 5.9 3 1 4 7 7 7 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 OQS06387.1 - 1.3e-06 28.9 2.2 0.11 13.1 0.0 4.3 1 1 3 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQS06387.1 - 0.047 14.2 1.1 78 4.4 0.0 4.8 5 1 1 6 6 6 0 Ankyrin repeat Pkinase PF00069.25 OQS06388.1 - 1.5e-74 250.7 0.0 2.5e-74 250.0 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQS06388.1 - 9.2e-34 116.9 0.0 1.5e-33 116.2 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase DUF1765 PF08578.10 OQS06388.1 - 2.5e-23 82.9 3.6 8.3e-23 81.2 3.6 2.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1765) Kinase-like PF14531.6 OQS06388.1 - 1.2e-08 34.6 0.0 2.5e-08 33.6 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 OQS06388.1 - 1.3e-06 27.9 0.1 3e-06 26.7 0.1 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 OQS06388.1 - 0.0006 18.7 0.0 0.0014 17.5 0.0 1.6 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 OQS06388.1 - 0.01 15.8 0.0 0.023 14.6 0.0 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 OQS06388.1 - 0.07 12.7 0.1 0.17 11.5 0.1 1.6 1 0 0 1 1 1 0 RIO1 family L27 PF02828.16 OQS06388.1 - 0.11 12.3 0.1 2.9 7.7 0.0 2.9 2 0 0 2 2 2 0 L27 domain fn3 PF00041.21 OQS06389.1 - 7.3e-37 125.6 2.6 5.2e-09 36.3 0.1 6.0 5 2 0 5 5 5 4 Fibronectin type III domain Pur_ac_phosph_N PF16656.5 OQS06389.1 - 1.3e-11 44.9 1.8 0.0074 16.8 0.0 5.1 5 0 0 5 5 5 3 Purple acid Phosphatase, N-terminal domain Ank_2 PF12796.7 OQS06389.1 - 1.1e-07 32.3 0.0 2.1e-07 31.4 0.0 1.3 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 OQS06389.1 - 2.9e-06 27.5 1.0 0.046 14.2 0.3 2.6 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.6 OQS06389.1 - 8.3e-06 26.2 0.1 2e-05 25.0 0.1 1.7 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQS06389.1 - 1.5e-05 25.0 0.2 0.28 11.9 0.0 3.0 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.6 OQS06389.1 - 0.0001 22.5 1.1 0.00076 19.7 0.1 2.4 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Arylsulfotran_N PF17425.2 OQS06389.1 - 0.0012 18.9 0.0 0.015 15.3 0.0 2.5 2 0 0 2 2 2 1 Arylsulfotransferase Ig-like domain Csm1_N PF18504.1 OQS06390.1 - 0.0022 18.3 7.5 0.29 11.5 0.1 5.1 4 0 0 4 4 4 1 Csm1 N-terminal domain NADH_B2 PF14813.6 OQS06390.1 - 0.043 13.6 0.2 4.8 7.0 0.0 3.1 2 0 0 2 2 2 0 NADH dehydrogenase 1 beta subcomplex subunit 2 Tup_N PF08581.10 OQS06390.1 - 2.1 8.7 16.6 2.2 8.6 0.3 5.2 5 0 0 5 5 5 0 Tup N-terminal RNase_T PF00929.24 OQS06392.1 - 0.00062 20.3 0.1 0.0019 18.8 0.1 1.8 1 1 0 1 1 1 1 Exonuclease Ras PF00071.22 OQS06393.1 - 1.3e-56 190.7 0.1 1.4e-56 190.5 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OQS06393.1 - 3.4e-20 72.5 0.1 4.6e-20 72.0 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OQS06393.1 - 8.1e-10 38.4 0.1 9.5e-10 38.2 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 OQS06393.1 - 8.3e-07 29.1 0.1 0.013 15.4 0.0 2.2 1 1 1 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 OQS06393.1 - 0.00024 20.7 0.1 0.0015 18.1 0.0 1.9 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 OQS06393.1 - 0.0015 18.5 0.1 0.0024 18.0 0.1 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 OQS06393.1 - 0.026 14.1 0.1 0.22 11.1 0.1 2.4 1 1 0 1 1 1 0 Ferrous iron transport protein B G-alpha PF00503.20 OQS06393.1 - 0.052 12.7 0.2 6.5 5.8 0.0 2.1 1 1 1 2 2 2 0 G-protein alpha subunit Septin PF00735.18 OQS06393.1 - 0.056 12.7 0.0 0.16 11.2 0.0 1.8 2 1 1 3 3 3 0 Septin AAA_16 PF13191.6 OQS06393.1 - 0.084 13.3 0.1 0.16 12.3 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain AAA_33 PF13671.6 OQS06393.1 - 0.11 12.7 0.0 0.15 12.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain Pkinase PF00069.25 OQS06394.1 - 1.5e-51 175.3 0.1 2.1e-51 174.8 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQS06394.1 - 1.6e-18 67.0 0.1 2.7e-18 66.2 0.1 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase zf-RING_2 PF13639.6 OQS06394.1 - 1.1e-09 38.4 6.5 4.1e-09 36.6 6.5 2.0 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 OQS06394.1 - 9.9e-08 31.7 6.1 9.9e-08 31.7 6.1 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 OQS06394.1 - 1.4e-07 31.1 8.4 2.1e-07 30.6 6.1 2.4 2 0 0 2 2 2 1 RING-like zinc finger zf-rbx1 PF12678.7 OQS06394.1 - 5e-07 29.9 7.0 1.2e-06 28.7 7.0 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 OQS06394.1 - 2.1e-05 24.3 5.8 5.7e-05 22.9 5.8 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OQS06394.1 - 0.0026 17.7 4.9 0.0063 16.4 4.9 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 OQS06394.1 - 0.0027 17.7 5.7 0.0071 16.3 5.7 1.8 1 0 0 1 1 1 1 RING-type zinc-finger Choline_kinase PF01633.20 OQS06394.1 - 0.014 15.0 0.3 0.027 14.1 0.3 1.5 1 0 0 1 1 1 0 Choline/ethanolamine kinase Zn_ribbon_17 PF17120.5 OQS06394.1 - 0.041 13.5 6.4 0.14 11.8 6.4 1.9 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type APH PF01636.23 OQS06394.1 - 0.053 13.4 0.0 0.1 12.5 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family zf-HC5HC2H PF13771.6 OQS06394.1 - 0.067 13.4 3.0 0.18 12.1 3.0 1.6 1 0 0 1 1 1 0 PHD-like zinc-binding domain Kdo PF06293.14 OQS06394.1 - 0.084 12.2 0.1 0.14 11.4 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family zf-HC5HC2H_2 PF13832.6 OQS06394.1 - 0.18 12.0 2.9 0.41 10.8 2.9 1.5 1 0 0 1 1 1 0 PHD-zinc-finger like domain zf-C3HC4_3 PF13920.6 OQS06394.1 - 0.25 11.2 7.1 0.8 9.6 7.1 1.9 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 OQS06394.1 - 0.29 11.2 2.5 0.64 10.1 2.5 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Leo1 PF04004.13 OQS06395.1 - 3.3e-34 118.1 0.3 3.3e-34 118.1 0.3 1.9 2 0 0 2 2 2 1 Leo1-like protein Pkinase PF00069.25 OQS06396.1 - 2.8e-62 210.5 0.0 4.8e-62 209.7 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQS06396.1 - 1.8e-44 152.0 0.0 3.1e-44 151.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase DUF547 PF04784.14 OQS06396.1 - 1.5e-23 83.2 0.0 2.7e-23 82.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF547 Response_reg PF00072.24 OQS06396.1 - 2.7e-21 75.8 0.1 6.3e-21 74.6 0.1 1.7 1 0 0 1 1 1 1 Response regulator receiver domain Kinase-like PF14531.6 OQS06396.1 - 1.1e-06 28.2 0.0 2e-06 27.4 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 OQS06396.1 - 0.057 12.2 0.0 0.096 11.4 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase Aa_trans PF01490.18 OQS06397.1 - 2.4e-71 240.6 54.6 3.9e-38 131.2 17.2 2.3 2 0 0 2 2 2 2 Transmembrane amino acid transporter protein Polysacc_deac_1 PF01522.21 OQS06397.1 - 3.5e-10 39.8 0.0 0.0024 17.8 0.0 3.7 3 0 0 3 3 3 3 Polysaccharide deacetylase Trp_Tyr_perm PF03222.13 OQS06397.1 - 7e-07 28.6 8.1 7e-07 28.6 8.1 4.9 5 0 0 5 5 5 3 Tryptophan/tyrosine permease family Pyr_excise PF03013.14 OQS06397.1 - 2.4e-06 27.5 0.6 0.027 14.4 0.0 2.7 2 0 0 2 2 2 2 Pyrimidine dimer DNA glycosylase DUF1515 PF07439.11 OQS06397.1 - 0.002 18.1 2.3 0.12 12.4 0.1 3.0 2 0 0 2 2 2 1 Protein of unknown function (DUF1515) BTB_2 PF02214.22 OQS06397.1 - 0.0041 17.5 0.0 0.012 15.9 0.0 1.8 1 0 0 1 1 1 1 BTB/POZ domain TMF_DNA_bd PF12329.8 OQS06397.1 - 0.062 13.3 4.2 0.12 12.4 4.2 1.5 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding DUF2229 PF09989.9 OQS06397.1 - 0.11 12.1 0.1 2 8.0 0.0 2.3 2 0 0 2 2 2 0 CoA enzyme activase uncharacterised domain (DUF2229) PGM_PMM_I PF02878.16 OQS06397.1 - 0.3 10.8 2.9 4.3 7.0 0.0 3.2 3 0 0 3 3 3 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I DUF3927 PF13064.6 OQS06397.1 - 2.5 8.1 5.2 23 5.0 0.5 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3927) CLASP_N PF12348.8 OQS06398.1 - 2.5e-12 46.8 1.7 4.9e-12 45.9 1.7 1.4 1 0 0 1 1 1 1 CLASP N terminal ERCC4 PF02732.15 OQS06399.1 - 3.3e-21 76.1 0.3 6.5e-21 75.2 0.3 1.5 1 0 0 1 1 1 1 ERCC4 domain HHH_8 PF14716.6 OQS06399.1 - 1.6e-08 34.8 0.1 3.3e-08 33.8 0.1 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix domain Pkinase PF00069.25 OQS06400.1 - 4.6e-74 249.1 0.0 5.6e-74 248.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQS06400.1 - 5e-44 150.5 0.0 6.3e-44 150.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 OQS06400.1 - 4.5e-06 25.9 0.5 6.1e-06 25.4 0.5 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 OQS06400.1 - 2.9e-05 23.5 1.1 4.5e-05 22.9 1.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 OQS06400.1 - 4.5e-05 22.4 0.3 0.00033 19.6 0.3 1.9 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 OQS06400.1 - 5.2e-05 22.7 0.1 0.001 18.5 0.0 2.2 2 1 0 2 2 2 1 Kinase-like RIO1 PF01163.22 OQS06400.1 - 0.00038 20.1 1.1 0.0012 18.5 1.1 1.7 1 1 0 1 1 1 1 RIO1 family Seadorna_VP7 PF07387.11 OQS06400.1 - 0.0012 18.0 0.0 0.0022 17.1 0.0 1.3 1 0 0 1 1 1 1 Seadornavirus VP7 APH PF01636.23 OQS06400.1 - 0.0014 18.6 2.4 0.0092 15.9 2.3 2.0 1 1 1 2 2 2 2 Phosphotransferase enzyme family FTA2 PF13095.6 OQS06400.1 - 0.022 14.4 0.8 0.11 12.1 0.4 2.0 1 1 1 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 YrbL-PhoP_reg PF10707.9 OQS06400.1 - 0.047 13.2 0.4 0.087 12.3 0.4 1.4 1 1 0 1 1 1 0 PhoP regulatory network protein YrbL tRNA_Me_trans PF03054.16 OQS06402.1 - 5.8e-115 383.9 0.0 8.8e-106 353.7 0.0 2.0 1 1 1 2 2 2 2 tRNA methyl transferase NAD_synthase PF02540.17 OQS06402.1 - 1.6e-06 27.4 0.0 7.1e-06 25.3 0.0 1.9 2 0 0 2 2 2 1 NAD synthase ATP_bind_3 PF01171.20 OQS06402.1 - 1.3e-05 25.1 0.0 7.4e-05 22.6 0.0 2.1 1 1 0 1 1 1 1 PP-loop family ThiI PF02568.14 OQS06402.1 - 0.0033 17.0 0.0 0.0066 16.1 0.0 1.5 1 0 0 1 1 1 1 Thiamine biosynthesis protein (ThiI) QueC PF06508.13 OQS06402.1 - 0.031 13.8 0.0 0.16 11.5 0.0 2.1 2 0 0 2 2 2 0 Queuosine biosynthesis protein QueC Asn_synthase PF00733.21 OQS06402.1 - 0.09 12.4 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 Asparagine synthase ATP-grasp_4 PF13535.6 OQS06403.1 - 1.1e-22 80.3 0.0 9e-12 44.9 0.0 2.4 2 0 0 2 2 2 2 ATP-grasp domain ATP-grasp_3 PF02655.14 OQS06403.1 - 2.9e-14 53.4 0.0 4.8e-07 30.0 0.0 2.4 2 0 0 2 2 2 2 ATP-grasp domain LAL_C2 PF18603.1 OQS06403.1 - 1e-13 51.2 0.0 8.8e-06 25.8 0.0 3.0 3 0 0 3 3 3 2 L-amino acid ligase C-terminal domain 2 GARS_A PF01071.19 OQS06403.1 - 1.2e-10 41.5 0.0 6.1e-05 22.9 0.0 2.5 2 0 0 2 2 2 2 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATPgrasp_Ter PF15632.6 OQS06403.1 - 1.3e-08 34.7 0.1 0.027 14.2 0.0 4.1 2 2 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon RimK PF08443.11 OQS06403.1 - 2.2e-07 30.7 0.0 0.00078 19.1 0.0 2.3 2 0 0 2 2 2 2 RimK-like ATP-grasp domain ATPgrasp_TupA PF14305.6 OQS06403.1 - 0.19 11.5 0.0 12 5.6 0.0 2.2 2 0 0 2 2 2 0 TupA-like ATPgrasp DUF4840 PF16128.5 OQS06404.1 - 0.019 15.0 1.7 0.023 14.7 1.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4840) PB1-F2 PF11986.8 OQS06404.1 - 0.037 14.2 0.5 0.051 13.8 0.5 1.2 1 0 0 1 1 1 0 Influenza A Proapoptotic protein DUF4141 PF13605.6 OQS06404.1 - 0.052 12.8 0.1 0.099 11.9 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4141) LMBR1 PF04791.16 OQS06404.1 - 0.089 11.7 3.2 0.11 11.4 3.2 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein Occludin_ELL PF07303.13 OQS06404.1 - 0.12 13.1 8.6 0.21 12.4 8.6 1.5 1 1 0 1 1 1 0 Occludin homology domain DUF883 PF05957.13 OQS06404.1 - 0.18 12.5 4.8 0.42 11.2 4.3 1.8 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF883) DASH_Hsk3 PF08227.11 OQS06404.1 - 0.34 11.3 7.8 0.38 11.1 3.2 2.7 2 1 0 2 2 2 0 DASH complex subunit Hsk3 like MDD_C PF18376.1 OQS06405.1 - 0.00037 20.3 0.0 0.00063 19.5 0.0 1.4 1 0 0 1 1 1 1 Mevalonate 5-diphosphate decarboxylase C-terminal domain Pkinase PF00069.25 OQS06406.1 - 6.4e-23 81.5 0.0 8.2e-23 81.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQS06406.1 - 1.5e-11 44.1 0.0 2.6e-11 43.3 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OQS06406.1 - 0.0011 18.3 0.0 0.0016 17.9 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Pkinase PF00069.25 OQS06407.1 - 2.4e-74 250.0 0.0 3.1e-74 249.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQS06407.1 - 7.1e-45 153.3 0.0 9.3e-45 152.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OQS06407.1 - 6.3e-07 29.0 0.1 7.1e-05 22.3 0.0 2.1 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.14 OQS06407.1 - 1.9e-05 24.1 0.0 3.3e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 OQS06407.1 - 0.024 13.5 0.1 0.034 12.9 0.1 1.5 1 1 0 1 1 1 0 Fungal protein kinase DUF1329 PF07044.11 OQS06407.1 - 0.024 13.9 0.1 0.033 13.5 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1329) YrbL-PhoP_reg PF10707.9 OQS06407.1 - 0.045 13.3 0.2 0.077 12.5 0.2 1.3 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Seadorna_VP7 PF07387.11 OQS06407.1 - 0.084 11.9 0.0 0.17 10.9 0.0 1.5 1 0 0 1 1 1 0 Seadornavirus VP7 APH PF01636.23 OQS06407.1 - 0.13 12.2 0.1 0.41 10.5 0.1 1.6 1 1 1 2 2 2 0 Phosphotransferase enzyme family TPR_2 PF07719.17 OQS06408.1 - 5e-16 57.4 0.4 0.0003 20.7 0.2 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.28 OQS06408.1 - 3.1e-14 52.1 0.1 9.3e-06 25.3 0.1 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 OQS06408.1 - 5.2e-13 48.4 4.4 5.1e-06 26.1 0.3 3.4 2 1 1 3 3 3 2 TPR repeat FYVE PF01363.21 OQS06408.1 - 2.5e-12 46.7 11.7 4.3e-12 46.0 11.7 1.4 1 0 0 1 1 1 1 FYVE zinc finger TPR_8 PF13181.6 OQS06408.1 - 3.1e-11 42.6 0.8 5.7e-05 23.0 0.1 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 OQS06408.1 - 2.3e-10 40.6 2.7 0.00016 21.9 0.0 3.5 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_14 PF13428.6 OQS06408.1 - 3.5e-09 36.7 5.9 0.007 17.1 0.1 4.1 2 1 2 4 4 3 3 Tetratricopeptide repeat TPR_16 PF13432.6 OQS06408.1 - 9.9e-07 29.3 10.4 5.2e-05 23.8 0.6 3.2 4 0 0 4 4 2 2 Tetratricopeptide repeat TPR_7 PF13176.6 OQS06408.1 - 1.2e-06 28.1 2.0 0.012 15.6 0.0 3.2 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.6 OQS06408.1 - 2e-06 28.1 2.4 0.75 10.6 0.0 4.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_10 PF13374.6 OQS06408.1 - 7.8e-06 25.6 3.1 0.032 14.1 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat Ank_5 PF13857.6 OQS06408.1 - 9.6e-06 25.8 0.0 0.0035 17.6 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) TPR_17 PF13431.6 OQS06408.1 - 1.2e-05 25.4 0.1 0.008 16.5 0.0 3.2 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.6 OQS06408.1 - 2.1e-05 25.0 8.4 4.1e-05 24.0 1.3 2.8 2 1 0 3 3 2 1 Tetratricopeptide repeat Ank_2 PF12796.7 OQS06408.1 - 4.9e-05 23.8 0.0 0.00013 22.5 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) ANAPC3 PF12895.7 OQS06408.1 - 5.2e-05 23.4 0.1 0.00014 22.0 0.1 1.8 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.6 OQS06408.1 - 0.00019 21.5 1.5 0.00097 19.2 1.3 2.3 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_21 PF09976.9 OQS06408.1 - 0.0024 17.6 0.8 0.0048 16.6 0.8 1.5 1 0 0 1 1 1 1 Tetratricopeptide repeat-like domain Ank_4 PF13637.6 OQS06408.1 - 0.0074 16.8 0.0 0.018 15.6 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (many copies) TPR_MalT PF17874.1 OQS06408.1 - 0.1 11.9 4.0 0.2 11.0 0.1 2.3 2 0 0 2 2 2 0 MalT-like TPR region Ank PF00023.30 OQS06408.1 - 0.14 12.7 0.2 5.9 7.5 0.0 2.6 2 0 0 2 2 2 0 Ankyrin repeat TPR_3 PF07720.12 OQS06408.1 - 0.79 9.8 2.6 7.2 6.7 0.1 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat MAS20 PF02064.15 OQS06408.1 - 2.9 8.0 5.7 3.3 7.8 0.1 2.9 3 0 0 3 3 3 0 MAS20 protein import receptor DUF2576 PF10845.8 OQS06409.1 - 0.021 14.4 0.4 0.052 13.2 0.1 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2576) Myb_DNA-binding PF00249.31 OQS06410.1 - 2.6e-31 107.6 11.9 9.1e-17 61.0 1.9 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OQS06410.1 - 2.8e-23 81.9 11.0 1.3e-15 57.4 1.5 2.5 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OQS06410.1 - 1.4e-06 28.1 4.5 2e-06 27.6 1.6 2.2 1 1 1 2 2 2 1 Myb DNA-binding like SLIDE PF09111.10 OQS06410.1 - 2.2e-06 27.7 0.6 0.0032 17.5 0.0 2.3 2 0 0 2 2 2 2 SLIDE Myb_DNA-bind_4 PF13837.6 OQS06410.1 - 0.0078 16.6 11.9 0.0094 16.3 1.3 3.2 3 1 0 3 3 3 2 Myb/SANT-like DNA-binding domain SANT_DAMP1_like PF16282.5 OQS06410.1 - 0.048 13.9 0.9 0.45 10.8 0.2 2.4 2 0 0 2 2 2 0 SANT/Myb-like domain of DAMP1 Exonuc_VII_L PF02601.15 OQS06410.1 - 0.11 12.0 0.4 0.13 11.8 0.4 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit UPF0160 PF03690.13 OQS06411.1 - 6.3e-128 426.9 0.0 7.4e-128 426.7 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0160) Arm PF00514.23 OQS06412.1 - 1.7e-08 34.2 1.2 0.73 10.0 0.0 6.2 6 0 0 6 6 6 3 Armadillo/beta-catenin-like repeat KAP PF05804.12 OQS06412.1 - 0.00059 18.1 1.6 0.043 12.0 0.0 2.5 2 1 0 2 2 2 2 Kinesin-associated protein (KAP) CTNNBL PF08216.11 OQS06412.1 - 0.049 13.8 0.1 0.41 10.9 0.0 2.7 2 0 0 2 2 2 0 Catenin-beta-like, Arm-motif containing nuclear DUF2278 PF10042.9 OQS06412.1 - 0.16 11.9 0.7 0.42 10.6 0.2 1.9 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2278) Dynactin_p22 PF07426.11 OQS06412.1 - 0.56 10.0 5.2 0.37 10.6 1.2 2.7 3 0 0 3 3 3 0 Dynactin subunit p22 NPR3 PF03666.13 OQS06412.1 - 4.4 6.0 7.9 0.97 8.2 0.0 2.6 3 0 0 3 3 3 0 Nitrogen Permease regulator of amino acid transport activity 3 Carn_acyltransf PF00755.20 OQS06413.1 - 7.9e-187 622.5 0.1 9.1e-187 622.3 0.1 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase Presenilin PF01080.17 OQS06415.1 - 2.4e-107 359.2 0.3 3.1e-107 358.8 0.3 1.1 1 0 0 1 1 1 1 Presenilin Pkinase PF00069.25 OQS06416.1 - 6.6e-64 215.8 0.0 1.2e-63 215.0 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQS06416.1 - 7e-33 114.0 0.0 2.5e-32 112.2 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase Ank_2 PF12796.7 OQS06416.1 - 2e-20 73.2 1.5 2.2e-15 57.0 0.5 2.6 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OQS06416.1 - 2.8e-18 65.7 7.5 1.1e-08 35.1 0.1 2.9 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 OQS06416.1 - 7.3e-18 64.1 8.3 7e-07 29.4 0.1 4.3 4 0 0 4 4 3 3 Ankyrin repeat Ank_4 PF13637.6 OQS06416.1 - 6.9e-17 61.6 1.7 1e-10 41.9 0.1 3.1 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQS06416.1 - 2.9e-14 51.8 4.1 0.00096 19.4 0.0 5.1 5 0 0 5 5 4 3 Ankyrin repeat PH PF00169.29 OQS06416.1 - 2.2e-13 50.6 0.5 5e-13 49.5 0.2 1.8 2 0 0 2 2 1 1 PH domain PH_9 PF15410.6 OQS06416.1 - 4.7e-05 23.7 0.0 0.00013 22.3 0.0 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain PH_11 PF15413.6 OQS06416.1 - 0.00015 22.1 1.1 0.00032 21.1 0.2 2.1 2 0 0 2 2 2 1 Pleckstrin homology domain APH PF01636.23 OQS06416.1 - 0.015 15.2 0.6 5.3 6.9 0.0 2.7 2 1 1 3 3 3 0 Phosphotransferase enzyme family Kinase-like PF14531.6 OQS06416.1 - 0.025 13.9 0.0 0.1 11.9 0.0 2.0 2 0 0 2 2 2 0 Kinase-like PH_6 PF15406.6 OQS06416.1 - 0.033 14.5 0.2 0.11 12.7 0.2 1.9 1 0 0 1 1 1 0 Pleckstrin homology domain FTA2 PF13095.6 OQS06416.1 - 0.043 13.4 0.1 10 5.7 0.1 2.4 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 TMF_DNA_bd PF12329.8 OQS06416.1 - 0.057 13.4 2.3 0.18 11.8 2.3 1.8 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding PH_13 PF16652.5 OQS06416.1 - 0.063 13.1 0.4 0.15 11.8 0.0 1.8 2 0 0 2 2 2 0 Pleckstrin homology domain NEMO PF11577.8 OQS06416.1 - 0.19 11.7 2.0 0.54 10.3 2.0 1.7 1 0 0 1 1 1 0 NF-kappa-B essential modulator NEMO Csm1_N PF18504.1 OQS06416.1 - 0.31 11.4 4.9 0.093 13.1 1.2 2.0 2 0 0 2 2 1 0 Csm1 N-terminal domain MTHFR PF02219.17 OQS06417.1 - 4.8e-64 216.4 0.0 5.5e-64 216.2 0.0 1.0 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase RRM_1 PF00076.22 OQS06418.1 - 4.9e-17 61.5 0.0 9e-17 60.7 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) K-box PF01486.17 OQS06418.1 - 0.017 15.3 3.1 0.052 13.7 3.1 1.6 1 1 1 2 2 2 0 K-box region Methyltransf_29 PF03141.16 OQS06418.1 - 0.055 12.0 0.0 0.069 11.7 0.0 1.0 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase RRM_5 PF13893.6 OQS06418.1 - 0.06 13.0 0.0 0.09 12.4 0.0 1.2 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) GRP PF07172.11 OQS06418.1 - 0.064 14.0 14.5 0.15 12.7 14.5 1.6 1 0 0 1 1 1 0 Glycine rich protein family SKA1 PF07160.12 OQS06418.1 - 0.071 13.0 1.2 0.081 12.8 1.2 1.1 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 1 YabA PF06156.13 OQS06418.1 - 0.082 13.6 0.6 0.11 13.1 0.6 1.2 1 0 0 1 1 1 0 Initiation control protein YabA Spectrin PF00435.21 OQS06418.1 - 0.17 12.4 4.0 2.1 8.9 3.6 2.1 1 1 1 2 2 2 0 Spectrin repeat DUF465 PF04325.13 OQS06418.1 - 0.19 11.8 2.0 0.34 11.0 2.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF465) APS_kinase PF01583.20 OQS06419.1 - 9.4e-64 214.1 0.0 1.6e-63 213.3 0.0 1.3 1 0 0 1 1 1 1 Adenylylsulphate kinase ATP-sulfurylase PF01747.17 OQS06419.1 - 8.6e-55 185.5 0.0 1.4e-54 184.8 0.0 1.3 1 0 0 1 1 1 1 ATP-sulfurylase Pyrophosphatase PF00719.19 OQS06419.1 - 2.9e-40 137.7 0.3 4.3e-40 137.1 0.3 1.3 1 0 0 1 1 1 1 Inorganic pyrophosphatase PUA_2 PF14306.6 OQS06419.1 - 2.8e-33 114.8 0.0 1.2e-32 112.7 0.0 2.1 2 0 0 2 2 2 1 PUA-like domain AAA_33 PF13671.6 OQS06419.1 - 1.1e-06 28.8 0.0 3.5e-06 27.2 0.0 1.8 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.10 OQS06419.1 - 0.0016 18.0 0.0 0.0028 17.1 0.0 1.3 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_18 PF13238.6 OQS06419.1 - 0.003 18.1 0.0 0.008 16.7 0.0 1.8 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 OQS06419.1 - 0.013 14.7 0.0 0.03 13.6 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin DUF815 PF05673.13 OQS06419.1 - 0.034 13.3 0.0 0.058 12.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_29 PF13555.6 OQS06419.1 - 0.054 13.2 0.1 0.13 12.0 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.27 OQS06419.1 - 0.085 13.4 0.0 0.19 12.3 0.0 1.5 1 0 0 1 1 1 0 ABC transporter SANT_DAMP1_like PF16282.5 OQS06420.1 - 4.1e-22 78.2 1.1 8.6e-22 77.1 1.1 1.6 1 0 0 1 1 1 1 SANT/Myb-like domain of DAMP1 DMAP1 PF05499.12 OQS06420.1 - 6.1e-10 39.2 0.5 6.1e-10 39.2 0.5 1.8 2 0 0 2 2 2 1 DNA methyltransferase 1-associated protein 1 (DMAP1) Myb_DNA-binding PF00249.31 OQS06420.1 - 0.031 14.5 0.2 0.14 12.4 0.1 2.1 2 0 0 2 2 2 0 Myb-like DNA-binding domain DUF1179 PF06678.11 OQS06420.1 - 0.12 12.4 1.1 0.34 10.9 0.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1179) Swi5 PF07061.11 OQS06420.1 - 2.8 8.1 7.7 29 4.8 0.8 3.5 3 0 0 3 3 3 0 Swi5 Chitin_bind_1 PF00187.19 OQS06421.1 - 3.3e-14 53.1 76.1 1.5e-05 25.4 16.5 4.5 5 0 0 5 5 5 3 Chitin recognition protein PHD PF00628.29 OQS06422.1 - 1.7e-10 40.6 4.3 5.1e-10 39.1 4.3 1.9 1 0 0 1 1 1 1 PHD-finger zf-PHD-like PF15446.6 OQS06422.1 - 0.025 14.2 2.0 0.025 14.2 2.0 1.9 2 0 0 2 2 2 0 PHD/FYVE-zinc-finger like domain zf-TAZ PF02135.16 OQS06422.1 - 0.037 14.5 8.6 0.17 12.4 5.8 2.9 2 1 0 2 2 2 0 TAZ zinc finger zf-RING_2 PF13639.6 OQS06422.1 - 0.037 14.3 4.3 0.037 14.3 4.3 3.6 4 1 0 4 4 4 0 Ring finger domain C1_2 PF03107.16 OQS06422.1 - 0.13 12.6 6.1 0.079 13.3 2.8 2.4 3 0 0 3 3 3 0 C1 domain BUD22 PF09073.10 OQS06422.1 - 0.2 11.0 8.9 0.26 10.6 8.9 1.1 1 0 0 1 1 1 0 BUD22 Guanylate_cyc PF00211.20 OQS06423.1 - 2.1e-91 304.5 2.0 6.1e-52 175.9 0.1 3.0 2 1 0 2 2 2 2 Adenylate and Guanylate cyclase catalytic domain PhoLip_ATPase_C PF16212.5 OQS06423.1 - 4.9e-44 151.0 28.5 4.9e-44 151.0 28.5 3.4 3 1 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal zf-CCCH PF00642.24 OQS06425.1 - 6.6e-10 38.7 9.0 1e-06 28.5 1.8 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RRM_1 PF00076.22 OQS06425.1 - 3.1e-05 23.7 0.0 7.4e-05 22.5 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf_CCCH_4 PF18345.1 OQS06425.1 - 5.3e-05 23.1 12.5 0.0015 18.5 2.6 2.5 2 0 0 2 2 2 2 Zinc finger domain Torus PF16131.5 OQS06425.1 - 0.00018 22.2 13.2 0.58 10.9 0.0 3.5 2 1 0 2 2 2 2 Torus domain zf-CCCH_4 PF18044.1 OQS06425.1 - 0.00046 19.9 9.9 0.0028 17.4 2.8 2.4 2 0 0 2 2 2 2 CCCH-type zinc finger IDEAL PF08858.10 OQS06425.1 - 0.02 14.6 1.6 0.02 14.6 1.6 3.7 4 1 0 4 4 4 0 IDEAL domain zf-CCCH_2 PF14608.6 OQS06425.1 - 0.035 14.6 10.3 0.22 12.0 0.5 2.5 3 0 0 3 3 2 0 RNA-binding, Nab2-type zinc finger DUF4778 PF16008.5 OQS06425.1 - 0.038 14.1 14.0 0.054 13.5 14.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4778) V_ATPase_I PF01496.19 OQS06425.1 - 0.98 7.3 9.9 1.1 7.2 9.9 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF5401 PF17380.2 OQS06425.1 - 1.6 6.7 31.7 2.1 6.3 31.7 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5401) Atg14 PF10186.9 OQS06425.1 - 1.7 7.6 15.6 2.4 7.1 15.6 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 zf-CCCH_3 PF15663.5 OQS06425.1 - 8.4 6.7 9.0 3.8 7.8 0.1 3.0 3 0 0 3 3 3 0 Zinc-finger containing family DUF763 PF05559.11 OQS06425.1 - 9.2 5.3 8.3 15 4.6 8.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF763) DEAD PF00270.29 OQS06426.1 - 8.5e-26 90.8 0.0 1.5e-25 90.0 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF1998 PF09369.10 OQS06426.1 - 1.7e-18 67.1 0.1 4.7e-18 65.7 0.1 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1998) Helicase_C PF00271.31 OQS06426.1 - 5e-12 46.2 0.0 2.5e-11 43.9 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 OQS06426.1 - 4.1e-07 30.1 0.0 7.8e-07 29.2 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit WASH_WAHD PF11945.8 OQS06427.1 - 6.3e-39 134.2 0.0 1.2e-38 133.4 0.0 1.3 1 0 0 1 1 1 1 WAHD domain of WASH complex WH2 PF02205.20 OQS06427.1 - 0.08 12.8 0.6 0.15 11.9 0.1 1.8 2 0 0 2 2 2 0 WH2 motif Abhydrolase_6 PF12697.7 OQS06428.1 - 1.1e-30 107.9 0.0 1.9e-09 38.4 0.0 3.7 2 2 1 3 3 3 3 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 OQS06428.1 - 3.2e-30 105.6 0.0 7.7e-06 25.7 0.0 6.1 4 1 1 5 5 5 5 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 OQS06428.1 - 3.9e-28 98.3 0.1 3.5e-10 39.5 0.0 5.4 3 3 0 3 3 3 3 Serine aminopeptidase, S33 Glycos_transf_1 PF00534.20 OQS06428.1 - 1.3e-11 44.4 0.0 4.9e-11 42.5 0.0 2.1 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 OQS06428.1 - 1.5e-09 38.3 0.0 5.3e-09 36.6 0.0 1.9 1 0 0 1 1 1 1 Glycosyl transferases group 1 CH PF00307.31 OQS06428.1 - 3.5e-09 36.8 0.1 1.1e-08 35.2 0.0 1.9 2 0 0 2 2 1 1 Calponin homology (CH) domain Abhydrolase_3 PF07859.13 OQS06428.1 - 2.4e-07 30.8 0.1 0.68 9.7 0.0 3.7 3 0 0 3 3 3 3 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 OQS06428.1 - 7.5e-06 25.6 0.1 5.8 6.3 0.0 5.4 5 0 0 5 5 5 1 Prolyl oligopeptidase family DLH PF01738.18 OQS06428.1 - 4.1e-05 23.2 0.1 1.3 8.5 0.0 4.5 4 0 0 4 4 4 2 Dienelactone hydrolase family Say1_Mug180 PF10340.9 OQS06428.1 - 0.00012 21.1 0.0 0.33 9.7 0.0 3.1 3 0 0 3 3 3 2 Steryl acetyl hydrolase Glyco_trans_1_2 PF13524.6 OQS06428.1 - 0.0019 18.5 0.5 0.012 15.9 0.0 2.7 3 0 0 3 3 1 1 Glycosyl transferases group 1 Abhydrolase_2 PF02230.16 OQS06428.1 - 0.0023 17.8 0.0 16 5.2 0.0 3.6 3 0 0 3 3 3 0 Phospholipase/Carboxylesterase BAAT_C PF08840.11 OQS06428.1 - 0.0047 16.9 0.2 31 4.4 0.0 4.6 4 0 0 4 4 4 0 BAAT / Acyl-CoA thioester hydrolase C terminal FSH1 PF03959.13 OQS06428.1 - 0.0085 15.8 2.1 39 3.8 0.0 4.9 7 0 0 7 7 7 0 Serine hydrolase (FSH1) Tup_N PF08581.10 OQS06428.1 - 0.012 15.9 1.7 0.012 15.9 1.7 4.7 4 1 0 4 4 3 0 Tup N-terminal Abhydrolase_4 PF08386.10 OQS06428.1 - 0.044 13.9 0.0 14 5.9 0.0 2.8 3 0 0 3 3 2 0 TAP-like protein Peptidase_S15 PF02129.18 OQS06428.1 - 0.049 13.2 1.5 4.8 6.7 0.0 4.8 6 0 0 6 6 6 0 X-Pro dipeptidyl-peptidase (S15 family) Aminotran_5 PF00266.19 OQS06429.1 - 1.8e-86 290.4 0.0 2.3e-86 290.1 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 OQS06429.1 - 5.6e-05 22.6 0.1 9.2e-05 21.9 0.1 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.17 OQS06429.1 - 0.046 13.0 0.2 0.078 12.3 0.2 1.3 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Holin_9 PF16936.5 OQS06429.1 - 0.086 13.0 0.1 0.17 12.1 0.1 1.4 1 0 0 1 1 1 0 Putative holin Proteasome PF00227.26 OQS06430.1 - 8.3e-51 172.2 0.3 1.1e-50 171.8 0.3 1.1 1 0 0 1 1 1 1 Proteasome subunit UDPGP PF01704.18 OQS06434.1 - 2.8e-148 494.0 0.0 2.7e-49 167.9 0.0 3.1 3 0 0 3 3 3 3 UTP--glucose-1-phosphate uridylyltransferase NTP_transf_3 PF12804.7 OQS06434.1 - 6.6e-11 42.8 0.5 0.0085 16.5 0.0 3.6 3 0 0 3 3 3 3 MobA-like NTP transferase domain PH PF00169.29 OQS06434.1 - 6.7e-07 29.8 0.5 2.6e-06 27.9 0.5 2.1 1 0 0 1 1 1 1 PH domain ADH_N PF08240.12 OQS06434.1 - 9e-07 28.8 0.0 2.2e-06 27.5 0.0 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Acetyltransf_19 PF18015.1 OQS06434.1 - 0.00049 20.3 0.1 9.9 6.4 0.0 3.6 3 0 0 3 3 3 2 Acetyltransferase (GNAT) domain DUF166 PF02593.14 OQS06434.1 - 0.1 12.1 0.0 0.22 11.1 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function GBP PF02263.19 OQS06435.1 - 1.2e-20 73.8 0.0 1.2e-20 73.8 0.0 3.0 4 0 0 4 4 4 1 Guanylate-binding protein, N-terminal domain Glutaminase PF04960.15 OQS06435.1 - 1.4 8.1 5.0 4.5 6.4 5.0 2.0 1 0 0 1 1 1 0 Glutaminase AAA_22 PF13401.6 OQS06435.1 - 6.4 7.1 0.0 6.4 7.1 0.0 4.9 5 2 0 5 5 5 0 AAA domain Prenyltrans PF00432.21 OQS06436.1 - 9.5e-60 198.0 15.8 1.1e-12 47.4 0.0 6.1 6 0 0 6 6 6 5 Prenyltransferase and squalene oxidase repeat SQHop_cyclase_N PF13249.6 OQS06436.1 - 1e-07 31.4 0.0 0.069 12.2 0.0 3.6 3 1 1 4 4 4 3 Squalene-hopene cyclase N-terminal domain SQHop_cyclase_C PF13243.6 OQS06436.1 - 1.4e-06 27.6 0.1 0.0052 15.9 0.0 3.2 2 1 1 3 3 3 2 Squalene-hopene cyclase C-terminal domain Ank_2 PF12796.7 OQS06438.1 - 0.00026 21.5 0.0 0.58 10.8 0.0 3.0 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OQS06438.1 - 0.00053 20.2 0.0 8.2 6.9 0.0 3.6 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQS06438.1 - 0.0041 17.5 0.0 28 5.7 0.0 3.8 4 0 0 4 4 4 1 Ankyrin repeat Ank_4 PF13637.6 OQS06438.1 - 0.0099 16.5 0.0 0.32 11.6 0.0 2.8 2 1 1 3 3 3 1 Ankyrin repeats (many copies) FG-GAP_2 PF14312.6 OQS06438.1 - 0.091 13.0 0.0 0.17 12.2 0.0 1.4 1 0 0 1 1 1 0 FG-GAP repeat p450 PF00067.22 OQS06439.1 - 1.2e-22 80.4 0.0 1.1e-20 73.9 0.0 2.5 1 1 0 1 1 1 1 Cytochrome P450 Cation_efflux PF01545.21 OQS06440.1 - 1.8e-92 308.5 17.1 3.3e-46 157.5 4.5 2.1 2 0 0 2 2 2 2 Cation efflux family BTB_2 PF02214.22 OQS06440.1 - 2.1e-09 37.6 0.0 4.2e-09 36.6 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain FAM176 PF14851.6 OQS06440.1 - 4.1e-06 26.5 0.0 0.0045 16.6 0.0 2.6 2 0 0 2 2 2 2 FAM176 family Ctr PF04145.15 OQS06440.1 - 0.0005 20.7 0.0 0.66 10.6 0.0 3.7 2 2 0 2 2 2 1 Ctr copper transporter family Zip PF02535.22 OQS06440.1 - 0.0012 18.1 22.4 0.046 12.9 5.6 3.0 2 1 1 3 3 3 2 ZIP Zinc transporter DUF4834 PF16118.5 OQS06440.1 - 0.0031 18.4 0.4 0.55 11.2 0.1 3.7 2 2 0 2 2 2 1 Domain of unknown function (DUF4834) TLP-20 PF06088.11 OQS06440.1 - 0.014 15.3 0.1 1.8 8.5 0.2 2.3 2 0 0 2 2 2 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) KIAA1328 PF15369.6 OQS06440.1 - 0.059 13.2 1.0 0.12 12.2 1.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein KIAA1328 HMG-CoA_red PF00368.18 OQS06440.1 - 0.12 11.4 4.2 0.72 8.8 0.2 2.6 3 0 0 3 3 3 0 Hydroxymethylglutaryl-coenzyme A reductase MCU PF04678.13 OQS06440.1 - 0.15 12.1 1.1 21 5.2 0.0 3.5 4 0 0 4 4 4 0 Mitochondrial calcium uniporter DUF1345 PF07077.11 OQS06440.1 - 0.17 11.6 4.9 4.4 7.0 0.5 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1345) Metal_resist PF13801.6 OQS06440.1 - 0.19 12.0 4.1 9.6 6.4 0.0 3.1 3 0 0 3 3 2 0 Heavy-metal resistance DUF5362 PF17319.2 OQS06440.1 - 4 7.3 19.6 0.24 11.2 0.9 3.6 4 0 0 4 4 4 0 Family of unknown function (DUF5362) Sulfotransfer_1 PF00685.27 OQS06441.1 - 2.2e-30 106.0 0.1 3.1e-30 105.6 0.1 1.2 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 OQS06441.1 - 0.00037 20.9 0.1 0.0025 18.3 0.1 2.2 2 1 0 2 2 2 1 Sulfotransferase family Uma2 PF05685.12 OQS06442.1 - 8.5e-05 22.2 0.0 0.0013 18.3 0.0 2.1 2 0 0 2 2 2 1 Putative restriction endonuclease CHIPS PF11434.8 OQS06442.1 - 0.19 11.6 1.1 0.26 11.1 0.3 1.6 2 0 0 2 2 2 0 Chemotaxis-inhibiting protein CHIPS TUDOR_5 PF18359.1 OQS06443.1 - 7.5e-78 256.1 72.8 2.9e-06 26.9 0.3 13.5 13 0 0 13 13 13 13 Histone methyltransferase Tudor domain 1 DUF1325 PF07039.11 OQS06443.1 - 1.3e-50 170.9 34.3 0.004 17.2 0.0 13.1 8 2 5 13 13 13 13 SGF29 tudor-like domain DUF4537 PF15057.6 OQS06443.1 - 2.8e-27 95.1 10.0 0.11 12.5 0.0 12.2 4 3 7 12 12 12 11 Domain of unknown function (DUF4537) Agenet PF05641.12 OQS06443.1 - 4.2e-25 88.0 29.2 1.1 9.7 0.0 13.6 13 0 0 13 13 13 11 Agenet domain 53-BP1_Tudor PF09038.10 OQS06443.1 - 1.2e-23 83.4 43.3 0.087 12.8 0.2 13.1 8 2 5 13 13 13 12 Tumour suppressor p53-binding protein-1 Tudor LBR_tudor PF09465.10 OQS06443.1 - 1.3e-16 60.2 58.6 0.41 10.5 0.2 13.0 13 0 0 13 13 13 11 Lamin-B receptor of TUDOR domain Nuc_deoxyri_tr2 PF15891.5 OQS06443.1 - 2.1e-06 28.0 0.4 1e+02 3.3 0.0 8.4 9 1 0 10 10 10 0 Nucleoside 2-deoxyribosyltransferase like DUF4259 PF14078.6 OQS06443.1 - 4e-05 24.4 9.6 1.8e+02 2.8 0.1 9.8 2 1 7 11 11 11 0 Domain of unknown function (DUF4259) DUF3221 PF11518.8 OQS06443.1 - 0.0031 17.8 38.8 25 5.3 0.1 11.8 12 0 0 12 12 12 0 Protein of unknown function (DUF3221) FKBP_C PF00254.28 OQS06443.1 - 0.016 15.5 33.8 68 3.9 0.2 11.1 12 0 0 12 12 12 0 FKBP-type peptidyl-prolyl cis-trans isomerase Bac_A_amyl_C PF18612.1 OQS06443.1 - 0.024 14.4 43.3 33 4.3 0.1 11.9 13 0 0 13 13 13 0 Bacterial Alpha amylase C-terminal domain GP63 PF17471.2 OQS06443.1 - 0.09 13.0 28.0 8.5 6.6 0.1 10.0 12 0 0 12 12 12 0 Gene product 63 DNA_pol_A_exo1 PF01612.20 OQS06444.1 - 2.1e-40 138.3 1.2 4e-40 137.4 1.2 1.5 1 0 0 1 1 1 1 3'-5' exonuclease HRDC PF00570.23 OQS06444.1 - 3.1e-13 49.5 0.0 9.7e-13 47.9 0.0 1.9 1 0 0 1 1 1 1 HRDC domain PMC2NT PF08066.12 OQS06444.1 - 7.8e-09 36.1 0.2 3.3e-08 34.1 0.3 2.1 2 0 0 2 2 2 1 PMC2NT (NUC016) domain DUF3042 PF11240.8 OQS06444.1 - 5.6 7.1 5.2 0.51 10.4 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3042) Ysc84 PF04366.12 OQS06446.1 - 2e-33 114.9 0.2 3.3e-33 114.1 0.2 1.4 1 0 0 1 1 1 1 Las17-binding protein actin regulator Peptidase_S10 PF00450.22 OQS06447.1 - 5.2e-107 358.8 2.5 7.5e-107 358.3 2.5 1.2 1 0 0 1 1 1 1 Serine carboxypeptidase Pkinase PF00069.25 OQS06447.1 - 1.6e-69 234.2 0.0 2.3e-69 233.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQS06447.1 - 1.8e-32 112.6 0.0 1e-31 110.2 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OQS06447.1 - 4.7e-06 26.1 0.0 0.00024 20.5 0.0 2.3 1 1 1 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 OQS06447.1 - 0.00022 20.3 0.3 0.00048 19.2 0.3 1.5 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 OQS06447.1 - 0.045 13.7 0.3 7.3 6.4 0.2 2.3 1 1 1 2 2 2 0 Phosphotransferase enzyme family Glyco_transf_20 PF00982.21 OQS06448.1 - 2.2e-101 339.9 0.0 4.2e-87 292.8 0.0 2.2 2 0 0 2 2 2 2 Glycosyltransferase family 20 Trehalose_PPase PF02358.16 OQS06448.1 - 7.3e-41 139.8 0.0 1.5e-40 138.8 0.0 1.5 1 0 0 1 1 1 1 Trehalose-phosphatase Hydrolase_3 PF08282.12 OQS06448.1 - 0.11 12.2 0.0 0.26 11.0 0.0 1.6 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase AAA_22 PF13401.6 OQS06449.1 - 0.00022 21.5 0.0 0.0007 19.9 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 OQS06449.1 - 0.00025 21.5 0.0 0.002 18.5 0.0 2.2 1 1 0 1 1 1 1 AAA ATPase domain AAA PF00004.29 OQS06449.1 - 0.0029 18.0 0.0 0.008 16.6 0.0 1.7 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 OQS06449.1 - 0.004 17.1 0.0 0.0081 16.1 0.0 1.5 1 1 0 1 1 1 1 NACHT domain AAA_25 PF13481.6 OQS06449.1 - 0.0068 16.0 0.0 0.036 13.7 0.0 1.9 2 0 0 2 2 2 1 AAA domain PhoH PF02562.16 OQS06449.1 - 0.043 13.3 0.0 0.061 12.8 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein ATPase_2 PF01637.18 OQS06449.1 - 0.085 12.8 0.0 0.15 12.0 0.0 1.6 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea TniB PF05621.11 OQS06449.1 - 0.14 11.5 0.0 0.26 10.6 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein AAA_14 PF13173.6 OQS06449.1 - 0.16 12.0 0.0 0.31 11.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain Asn_synthase PF00733.21 OQS06450.1 - 9.3e-21 74.9 0.0 4.6e-15 56.1 0.1 2.0 1 1 1 2 2 2 2 Asparagine synthase QueC PF06508.13 OQS06450.1 - 0.13 11.7 0.0 0.5 9.8 0.0 1.9 1 1 0 1 1 1 0 Queuosine biosynthesis protein QueC DZR PF12773.7 OQS06450.1 - 0.28 11.2 4.9 0.15 12.1 2.2 1.9 2 0 0 2 2 2 0 Double zinc ribbon F_bP_aldolase PF01116.20 OQS06452.1 - 1.1e-88 297.3 0.0 1.7e-88 296.8 0.0 1.3 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II LRR_4 PF12799.7 OQS06452.1 - 1.2e-15 57.3 17.3 9.1e-06 25.9 0.0 4.3 3 1 3 6 6 6 5 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 OQS06452.1 - 1.1e-14 54.4 5.4 1.8e-13 50.3 2.8 2.3 1 1 1 2 2 2 2 Leucine-rich repeat LRR_8 PF13855.6 OQS06452.1 - 8.7e-09 35.0 15.5 0.0013 18.4 0.0 3.3 2 2 0 2 2 2 2 Leucine rich repeat LcrG PF07216.12 OQS06452.1 - 0.011 15.6 0.3 0.044 13.7 0.1 2.2 2 1 0 2 2 2 0 LcrG protein LRR_6 PF13516.6 OQS06452.1 - 1.4 9.2 9.2 35 4.8 0.0 4.8 5 0 0 5 5 5 0 Leucine Rich repeat Choline_transpo PF04515.12 OQS06453.1 - 8.9e-92 307.8 31.3 8.9e-92 307.8 31.3 3.0 3 0 0 3 3 3 1 Plasma-membrane choline transporter PWI PF01480.17 OQS06454.1 - 2.2e-08 34.3 2.0 3.5e-08 33.6 0.1 2.4 3 0 0 3 3 3 1 PWI domain zf-U11-48K PF05253.12 OQS06454.1 - 0.0032 17.3 0.6 0.0032 17.3 0.6 1.9 2 0 0 2 2 2 1 U11-48K-like CHHC zinc finger DMP12 PF16779.5 OQS06454.1 - 0.034 14.1 0.1 0.089 12.8 0.1 1.7 1 0 0 1 1 1 0 DNA-mimic protein CDC24 PF06395.11 OQS06454.1 - 0.19 12.0 0.9 3 8.1 0.1 3.0 2 1 1 3 3 3 0 CDC24 Calponin eIF3g PF12353.8 OQS06455.1 - 1e-31 109.9 1.8 1.9e-31 109.0 1.8 1.5 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit G RRM_1 PF00076.22 OQS06455.1 - 1e-18 66.9 0.0 1.7e-18 66.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PHM7_cyt PF14703.6 OQS06455.1 - 0.076 13.2 1.8 3.5 7.8 0.1 3.0 2 1 1 3 3 3 0 Cytosolic domain of 10TM putative phosphate transporter Toprim_3 PF13362.6 OQS06455.1 - 0.19 12.1 0.0 0.52 10.7 0.0 1.8 2 0 0 2 2 2 0 Toprim domain DUF4878 PF12870.7 OQS06456.1 - 0.032 14.6 0.3 0.052 13.9 0.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4878) Prefoldin_3 PF13758.6 OQS06457.1 - 0.0028 17.7 3.4 0.0028 17.7 3.4 2.8 1 1 1 2 2 2 1 Prefoldin subunit PX PF00787.24 OQS06457.1 - 0.067 13.2 0.7 0.11 12.4 0.7 1.5 1 0 0 1 1 1 0 PX domain DUF724 PF05266.14 OQS06457.1 - 0.3 10.9 21.7 0.83 9.4 8.7 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF724) OmpH PF03938.14 OQS06457.1 - 0.7 10.2 25.2 0.17 12.2 10.4 2.3 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) Tup_N PF08581.10 OQS06457.1 - 1.9 8.8 22.4 0.31 11.4 2.4 3.8 1 1 3 4 4 4 0 Tup N-terminal KxDL PF10241.9 OQS06457.1 - 3.4 8.0 20.9 1.3 9.3 1.4 3.1 2 1 1 3 3 3 0 Uncharacterized conserved protein FUSC PF04632.12 OQS06457.1 - 7.2 5.0 8.3 10 4.5 8.3 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family AAA PF00004.29 OQS06458.1 - 1.6e-53 180.7 0.0 8.8e-39 132.9 0.0 2.9 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 OQS06458.1 - 3.7e-13 49.0 1.2 1.3e-10 40.9 0.2 2.5 2 0 0 2 2 2 1 AAA+ lid domain AAA_2 PF07724.14 OQS06458.1 - 1e-07 32.3 0.0 0.00015 21.9 0.0 2.5 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) NACHT PF05729.12 OQS06458.1 - 1.2e-07 31.8 4.4 0.0039 17.1 0.6 3.6 2 2 1 3 3 3 2 NACHT domain AAA_14 PF13173.6 OQS06458.1 - 2e-07 31.1 0.0 0.024 14.7 0.0 2.4 2 0 0 2 2 2 2 AAA domain TsaE PF02367.17 OQS06458.1 - 2.7e-07 30.6 0.6 0.0029 17.6 0.0 2.5 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_33 PF13671.6 OQS06458.1 - 2.8e-07 30.8 0.0 0.00018 21.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.14 OQS06458.1 - 4.5e-07 29.9 0.3 0.00021 21.3 0.0 3.1 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 OQS06458.1 - 5.2e-07 30.2 7.5 0.0033 17.8 0.1 4.4 3 2 1 4 4 4 2 AAA ATPase domain AAA_7 PF12775.7 OQS06458.1 - 3.8e-06 26.5 0.3 0.012 15.1 0.0 3.5 2 2 0 2 2 2 1 P-loop containing dynein motor region RNA_helicase PF00910.22 OQS06458.1 - 3.7e-05 24.1 0.0 0.015 15.6 0.0 3.1 3 0 0 3 3 3 1 RNA helicase AAA_22 PF13401.6 OQS06458.1 - 0.00032 21.0 3.9 0.14 12.5 0.1 4.2 4 2 0 4 4 2 1 AAA domain RuvB_N PF05496.12 OQS06458.1 - 0.0004 20.2 0.0 0.039 13.7 0.0 3.1 3 0 0 3 3 3 1 Holliday junction DNA helicase RuvB P-loop domain Sigma54_activat PF00158.26 OQS06458.1 - 0.00045 20.0 0.0 0.68 9.6 0.0 2.7 2 0 0 2 2 2 2 Sigma-54 interaction domain TIP49 PF06068.13 OQS06458.1 - 0.00046 19.5 0.2 0.18 10.9 0.0 2.2 2 0 0 2 2 2 2 TIP49 P-loop domain IstB_IS21 PF01695.17 OQS06458.1 - 0.00049 19.9 0.5 1.3 8.8 0.2 2.8 2 1 1 3 3 3 2 IstB-like ATP binding protein Bac_DnaA PF00308.18 OQS06458.1 - 0.0013 18.6 0.1 0.41 10.4 0.0 2.6 2 1 0 2 2 2 1 Bacterial dnaA protein DUF815 PF05673.13 OQS06458.1 - 0.0015 17.8 0.2 0.081 12.1 0.0 2.9 3 0 0 3 3 3 1 Protein of unknown function (DUF815) AAA_3 PF07726.11 OQS06458.1 - 0.002 18.0 0.0 0.21 11.4 0.0 2.5 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.21 OQS06458.1 - 0.0023 17.4 0.1 0.17 11.3 0.0 2.8 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI Rad17 PF03215.15 OQS06458.1 - 0.0026 17.7 0.0 0.026 14.4 0.0 2.2 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_18 PF13238.6 OQS06458.1 - 0.003 18.1 0.0 0.14 12.7 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.6 OQS06458.1 - 0.0049 17.1 0.0 0.32 11.2 0.0 2.3 2 0 0 2 2 2 1 AAA domain AFG1_ATPase PF03969.16 OQS06458.1 - 0.0059 15.5 0.1 0.65 8.8 0.0 2.6 2 1 0 2 2 2 1 AFG1-like ATPase AAA_25 PF13481.6 OQS06458.1 - 0.0061 16.1 0.9 0.25 10.9 0.1 3.1 3 1 1 4 4 4 1 AAA domain ATPase_2 PF01637.18 OQS06458.1 - 0.0062 16.5 0.1 0.65 9.9 0.1 3.1 2 2 2 4 4 4 1 ATPase domain predominantly from Archaea AAA_24 PF13479.6 OQS06458.1 - 0.0091 15.7 0.1 0.89 9.2 0.0 2.7 2 1 0 2 2 2 1 AAA domain TniB PF05621.11 OQS06458.1 - 0.012 15.0 0.0 0.18 11.2 0.0 2.7 3 0 0 3 3 2 0 Bacterial TniB protein ABC_tran PF00005.27 OQS06458.1 - 0.029 14.9 0.1 0.63 10.6 0.0 2.6 2 0 0 2 2 2 0 ABC transporter AAA_30 PF13604.6 OQS06458.1 - 0.03 14.0 0.0 7.3 6.3 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.6 OQS06458.1 - 0.091 13.1 0.0 9.2 6.6 0.0 2.9 3 0 0 3 3 2 0 AAA domain CSD PF00313.22 OQS06458.1 - 0.12 12.3 0.1 0.33 10.8 0.1 1.7 1 0 0 1 1 1 0 'Cold-shock' DNA-binding domain SRPRB PF09439.10 OQS06458.1 - 0.14 11.6 0.9 0.79 9.1 0.0 2.6 3 1 0 3 3 2 0 Signal recognition particle receptor beta subunit NTPase_1 PF03266.15 OQS06458.1 - 0.14 12.0 0.2 9.5 6.1 0.0 2.8 3 0 0 3 3 2 0 NTPase Guanylate_kin PF00625.21 OQS06458.1 - 0.18 11.5 0.0 23 4.6 0.0 2.5 1 1 1 2 2 2 0 Guanylate kinase AAA_29 PF13555.6 OQS06458.1 - 0.21 11.4 1.8 4.4 7.1 0.1 3.1 3 0 0 3 3 3 0 P-loop containing region of AAA domain FA_hydroxylase PF04116.13 OQS06459.1 - 2.4e-30 105.6 21.1 5.3e-30 104.5 15.5 2.3 2 0 0 2 2 2 2 Fatty acid hydroxylase superfamily Robl_LC7 PF03259.17 OQS06460.1 - 4.7e-08 32.7 0.0 5.8e-08 32.4 0.0 1.1 1 0 0 1 1 1 1 Roadblock/LC7 domain Peptidase_M16 PF00675.20 OQS06461.1 - 3.1e-27 95.4 0.4 8.5e-25 87.5 0.0 2.4 2 0 0 2 2 2 2 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 OQS06461.1 - 4.5e-13 49.6 0.0 6.8e-12 45.8 0.0 2.6 3 0 0 3 3 3 1 Peptidase M16 inactive domain SRP68 PF16969.5 OQS06461.1 - 0.054 12.5 1.1 0.075 12.0 1.1 1.2 1 0 0 1 1 1 0 RNA-binding signal recognition particle 68 Ribosomal_L20 PF00453.18 OQS06461.1 - 0.066 13.3 0.0 0.15 12.1 0.0 1.6 1 0 0 1 1 1 0 Ribosomal protein L20 EF-hand_1 PF00036.32 OQS06462.1 - 7.6e-42 137.8 14.2 2.9e-10 38.9 1.3 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 OQS06462.1 - 1e-35 122.0 3.4 5.3e-18 65.2 1.3 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 OQS06462.1 - 1.6e-32 111.1 12.1 2.1e-16 59.5 0.9 4.0 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.6 OQS06462.1 - 2.2e-30 101.9 7.7 1.3e-09 37.2 0.1 4.4 4 1 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 OQS06462.1 - 8.7e-27 91.4 10.5 2.3e-06 26.8 0.2 4.2 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.6 OQS06462.1 - 2.2e-16 59.9 0.2 2.3e-09 37.4 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 OQS06462.1 - 7.2e-10 38.8 0.8 0.00014 21.8 0.2 2.2 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 OQS06462.1 - 2e-08 34.5 0.0 0.0022 18.3 0.1 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_11 PF08976.11 OQS06462.1 - 4.2e-07 30.8 0.0 0.00016 22.5 0.0 2.1 1 1 1 2 2 2 1 EF-hand domain UPF0154 PF03672.13 OQS06462.1 - 8.7e-06 25.7 0.9 0.042 13.9 0.0 3.3 3 1 1 4 4 4 2 Uncharacterised protein family (UPF0154) EFhand_Ca_insen PF08726.10 OQS06462.1 - 6.4e-05 23.0 1.0 0.00037 20.5 0.1 2.4 2 2 0 2 2 2 1 Ca2+ insensitive EF hand Dockerin_1 PF00404.18 OQS06462.1 - 0.00027 21.0 3.9 0.045 13.9 0.3 2.8 1 1 0 2 2 2 2 Dockerin type I domain RNA_pol_Rpb4 PF03874.16 OQS06462.1 - 0.0013 19.0 0.4 0.73 10.2 0.1 2.5 3 0 0 3 3 2 1 RNA polymerase Rpb4 TerB PF05099.13 OQS06462.1 - 0.0017 18.3 0.3 0.58 10.1 0.0 2.3 1 1 1 2 2 2 1 Tellurite resistance protein TerB DUF1103 PF06513.11 OQS06462.1 - 0.0019 17.9 2.1 0.0022 17.7 2.1 1.1 1 0 0 1 1 1 1 Repeat of unknown function (DUF1103) DUF3349 PF11829.8 OQS06462.1 - 0.0019 18.9 0.4 1.2 10.0 0.0 2.7 1 1 2 3 3 3 1 Protein of unknown function (DUF3349) Caleosin PF05042.13 OQS06462.1 - 0.0024 17.8 1.4 0.49 10.3 0.0 3.5 1 1 3 4 4 4 1 Caleosin related protein DUF5580 PF17743.1 OQS06462.1 - 0.0074 14.9 0.0 0.0074 14.9 0.0 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF5580) DUF853 PF05872.12 OQS06462.1 - 0.022 13.4 0.1 0.6 8.6 0.0 2.0 1 1 0 2 2 2 0 Bacterial protein of unknown function (DUF853) Poly_export PF02563.16 OQS06462.1 - 0.028 14.6 0.1 4.1 7.7 0.0 3.1 1 1 1 3 3 3 0 Polysaccharide biosynthesis/export protein SurA_N_2 PF13623.6 OQS06462.1 - 0.029 14.2 0.6 1.7 8.5 0.1 2.2 1 1 1 2 2 2 0 SurA N-terminal domain MotA_activ PF09114.10 OQS06462.1 - 0.035 14.2 0.4 0.54 10.4 0.0 2.3 1 1 0 2 2 2 0 Transcription factor MotA, activation domain dCache_2 PF08269.11 OQS06462.1 - 0.047 12.9 0.1 3.8 6.6 0.1 2.2 1 1 0 2 2 2 0 Cache domain Fe_hyd_lg_C PF02906.14 OQS06462.1 - 0.061 13.0 1.0 0.24 11.0 1.0 1.9 1 1 0 1 1 1 0 Iron only hydrogenase large subunit, C-terminal domain EF-hand_14 PF17959.1 OQS06462.1 - 0.075 13.4 0.2 9.2 6.7 0.0 2.4 1 1 1 2 2 2 0 EF-hand domain SapB_1 PF05184.15 OQS06462.1 - 0.27 11.3 2.7 27 4.9 0.0 3.5 4 0 0 4 4 4 0 Saposin-like type B, region 1 Rsm22 PF09243.10 OQS06464.1 - 8.2e-48 163.0 0.0 1.5e-47 162.1 0.0 1.5 1 0 0 1 1 1 1 Mitochondrial small ribosomal subunit Rsm22 DnaJ_C PF01556.18 OQS06464.1 - 4.2e-26 91.8 0.0 6.6e-26 91.2 0.0 1.3 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.19 OQS06464.1 - 2.4e-09 37.4 14.7 5.9e-09 36.2 14.7 1.7 1 0 0 1 1 1 1 DnaJ central domain Methyltransf_23 PF13489.6 OQS06464.1 - 1.6e-07 31.3 0.0 3e-07 30.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OQS06464.1 - 3e-05 24.7 0.0 6.4e-05 23.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OQS06464.1 - 0.00035 20.4 0.0 0.00096 19.0 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Anti-TRAP PF15777.5 OQS06464.1 - 0.093 12.7 12.4 0.11 12.4 1.7 2.6 1 1 1 2 2 2 0 Tryptophan RNA-binding attenuator protein inhibitory protein HypA PF01155.19 OQS06464.1 - 0.3 11.1 8.3 3.6 7.6 0.7 2.6 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Lar_restr_allev PF14354.6 OQS06464.1 - 0.62 10.5 7.0 0.82 10.1 2.1 2.9 1 1 1 2 2 2 0 Restriction alleviation protein Lar DZR PF12773.7 OQS06464.1 - 2.8 8.0 7.7 10 6.2 7.8 1.9 1 1 0 1 1 1 0 Double zinc ribbon FdhE PF04216.12 OQS06464.1 - 4.1 7.2 5.5 8.3 6.2 5.5 1.4 1 0 0 1 1 1 0 Protein involved in formate dehydrogenase formation zf-C3HC4_3 PF13920.6 OQS06464.1 - 5.5 6.9 8.2 17 5.4 0.8 2.6 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Pkinase PF00069.25 OQS06466.1 - 3.8e-38 131.4 0.0 7.8e-38 130.3 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQS06466.1 - 1.4e-16 60.6 0.0 3.2e-16 59.4 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase HRDC PF00570.23 OQS06466.1 - 2.5e-09 37.0 0.0 5.9e-09 35.8 0.0 1.7 1 0 0 1 1 1 1 HRDC domain KIX_2 PF16987.5 OQS06466.1 - 4.1e-08 33.1 0.3 1.2e-07 31.6 0.3 1.9 1 0 0 1 1 1 1 KIX domain Kdo PF06293.14 OQS06466.1 - 2.8e-05 23.6 0.5 5.7e-05 22.6 0.5 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family KASH_CCD PF14662.6 OQS06466.1 - 0.0049 16.7 4.5 0.012 15.4 4.5 1.6 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 or KASH APH PF01636.23 OQS06466.1 - 0.0064 16.4 0.2 0.0064 16.4 0.2 2.0 2 0 0 2 2 2 1 Phosphotransferase enzyme family EGF_Tenascin PF18720.1 OQS06466.1 - 0.013 15.5 2.4 0.044 13.8 2.4 1.9 1 0 0 1 1 1 0 Tenascin EGF domain RIO1 PF01163.22 OQS06466.1 - 0.015 14.9 0.1 0.031 13.9 0.1 1.4 1 0 0 1 1 1 0 RIO1 family Choline_kinase PF01633.20 OQS06466.1 - 0.1 12.1 0.2 0.2 11.2 0.2 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase YabA PF06156.13 OQS06466.1 - 0.13 12.9 4.4 0.073 13.7 1.9 1.8 2 0 0 2 2 1 0 Initiation control protein YabA Lzipper-MIP1 PF14389.6 OQS06466.1 - 5.3 7.4 10.2 0.22 11.8 0.9 3.3 3 1 1 4 4 4 0 Leucine-zipper of ternary complex factor MIP1 CxC6 PF18721.1 OQS06467.1 - 0.0057 16.9 2.9 0.017 15.4 1.7 2.2 2 0 0 2 2 2 1 CxC6 like cysteine cluster associated with KDZ transposases WW PF00397.26 OQS06469.1 - 0.00026 21.0 0.3 0.00059 19.9 0.3 1.7 1 0 0 1 1 1 1 WW domain FAIM1 PF06905.13 OQS06469.1 - 0.0018 18.0 0.1 0.042 13.5 0.0 2.4 2 0 0 2 2 2 1 Fas apoptotic inhibitory molecule (FAIM1) PCC_BT PF18140.1 OQS06469.1 - 0.05 13.9 0.1 0.87 9.9 0.0 2.3 2 0 0 2 2 2 0 Propionyl-coenzyme A carboxylase BT domain FA_hydroxylase PF04116.13 OQS06470.1 - 9.4e-16 58.4 5.0 1.3e-15 58.0 5.0 1.2 1 0 0 1 1 1 1 Fatty acid hydroxylase superfamily AMP-binding PF00501.28 OQS06471.1 - 2.6e-101 339.3 0.0 3.1e-101 339.0 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 OQS06471.1 - 2.6e-17 63.6 0.0 5.2e-17 62.6 0.0 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Zn-ribbon_8 PF09723.10 OQS06472.1 - 0.00057 19.9 0.5 0.003 17.6 0.5 2.3 1 0 0 1 1 1 1 Zinc ribbon domain NHL PF01436.21 OQS06474.1 - 3.4e-23 80.4 36.9 0.0015 18.5 0.1 11.3 11 0 0 11 11 11 8 NHL repeat DUF5128 PF17170.4 OQS06474.1 - 3.3e-06 26.5 5.9 0.19 10.9 0.0 5.4 5 1 1 6 6 6 2 6-bladed beta-propeller TolB_like PF15869.5 OQS06474.1 - 1.7e-05 24.2 0.0 0.2 10.9 0.0 3.3 2 1 0 3 3 3 2 TolB-like 6-blade propeller-like SGL PF08450.12 OQS06474.1 - 0.0097 15.5 0.1 0.53 9.8 0.0 3.7 5 0 0 5 5 5 1 SMP-30/Gluconolactonase/LRE-like region Lactonase PF10282.9 OQS06474.1 - 0.11 11.7 0.0 4.4 6.4 0.0 2.9 2 1 1 3 3 3 0 Lactonase, 7-bladed beta-propeller TP6A_N PF04406.14 OQS06475.1 - 3.8e-17 62.0 0.1 7.4e-17 61.1 0.1 1.5 1 0 0 1 1 1 1 Type IIB DNA topoisomerase FA_hydroxylase PF04116.13 OQS06476.1 - 5.6e-30 104.4 15.0 5.6e-30 104.4 15.0 1.9 2 1 0 2 2 2 1 Fatty acid hydroxylase superfamily DUF1418 PF07214.12 OQS06476.1 - 0.48 10.3 2.2 0.71 9.8 0.6 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1418) Ribosomal_L35Ae PF01247.18 OQS06477.1 - 1.2e-41 140.8 1.5 2.1e-41 140.0 1.5 1.4 1 0 0 1 1 1 1 Ribosomal protein L35Ae Tetraspanin PF00335.20 OQS06477.1 - 0.00017 21.4 9.2 0.0003 20.6 9.2 1.4 1 0 0 1 1 1 1 Tetraspanin family N6_Mtase PF02384.16 OQS06478.1 - 0.00021 20.7 0.0 0.00035 19.9 0.0 1.3 1 0 0 1 1 1 1 N-6 DNA Methylase MTS PF05175.14 OQS06478.1 - 0.00087 18.9 0.0 0.0013 18.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain DUF775 PF05603.12 OQS06478.1 - 0.015 14.8 0.2 0.03 13.8 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF775) Eco57I PF07669.11 OQS06478.1 - 0.021 15.3 0.1 0.087 13.3 0.0 2.1 2 0 0 2 2 2 0 Eco57I restriction-modification methylase Ank_4 PF13637.6 OQS06479.1 - 0.0025 18.4 0.2 1.8 9.3 0.1 3.1 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 OQS06479.1 - 0.0046 17.2 0.4 1.2 9.6 0.1 3.1 2 1 1 3 3 3 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 OQS06479.1 - 0.025 15.1 0.1 12 6.6 0.0 2.3 2 1 0 2 2 2 0 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OQS06479.1 - 0.13 12.9 0.1 86 4.2 0.0 3.4 3 0 0 3 3 3 0 Ankyrin repeat DEAD PF00270.29 OQS06480.1 - 5.4e-43 146.8 0.0 1e-42 145.9 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OQS06480.1 - 1.3e-27 96.3 0.0 1.9e-24 86.2 0.0 3.2 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 OQS06480.1 - 0.00022 21.3 0.1 0.00057 19.9 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 OQS06480.1 - 0.00082 18.7 0.2 0.0019 17.5 0.0 1.7 1 1 1 2 2 2 1 ERCC3/RAD25/XPB C-terminal helicase 3H PF02829.14 OQS06480.1 - 0.1 12.9 0.1 0.3 11.4 0.1 1.7 1 0 0 1 1 1 0 3H domain Pkinase PF00069.25 OQS06481.1 - 6.6e-53 179.8 1.9 1.2e-37 129.8 0.0 4.1 3 1 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 OQS06481.1 - 6.8e-30 104.2 0.0 2.7e-12 46.5 0.0 4.0 4 0 0 4 4 4 3 Protein tyrosine kinase tRNA-synt_His PF13393.6 OQS06481.1 - 9.7e-17 61.2 0.0 9.5e-15 54.7 0.0 2.8 1 1 0 1 1 1 1 Histidyl-tRNA synthetase RWD PF05773.22 OQS06481.1 - 2.3e-12 47.2 0.1 1e-11 45.2 0.1 2.2 1 0 0 1 1 1 1 RWD domain Kinase-like PF14531.6 OQS06481.1 - 3.7e-07 29.8 0.1 0.0028 17.0 0.0 3.5 3 0 0 3 3 3 2 Kinase-like DrsE_2 PF13686.6 OQS06481.1 - 0.095 12.6 0.1 0.23 11.4 0.1 1.6 1 0 0 1 1 1 0 DsrE/DsrF/DrsH-like family Secretin_N_2 PF07655.13 OQS06481.1 - 7.9 7.1 6.5 27 5.4 0.6 2.9 2 0 0 2 2 2 0 Secretin N-terminal domain Ank_5 PF13857.6 OQS06482.1 - 0.1 12.9 0.0 5.6 7.4 0.0 2.3 2 0 0 2 2 2 0 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQS06482.1 - 0.17 12.5 0.0 25 5.9 0.0 2.9 3 0 0 3 3 3 0 Ankyrin repeat Pkinase PF00069.25 OQS06483.1 - 4e-40 137.8 0.0 5.6e-39 134.1 0.0 2.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQS06483.1 - 6.5e-21 74.8 0.0 1.2e-20 73.9 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OQS06483.1 - 2.5e-06 26.5 0.0 3.4e-06 26.1 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 OQS06483.1 - 7.2e-05 22.8 0.2 0.00037 20.5 0.1 2.0 1 1 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 OQS06483.1 - 0.00042 19.7 0.0 0.00064 19.1 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 OQS06483.1 - 0.0041 16.5 0.0 0.0058 16.0 0.0 1.2 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.22 OQS06483.1 - 0.012 15.3 0.0 0.016 14.8 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Haspin_kinase PF12330.8 OQS06483.1 - 0.039 12.9 0.0 0.049 12.6 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Choline_kinase PF01633.20 OQS06483.1 - 0.039 13.5 0.0 0.078 12.5 0.0 1.4 1 1 0 1 1 1 0 Choline/ethanolamine kinase MSC PF09402.10 OQS06484.1 - 1.4e-15 57.6 9.4 6.8e-15 55.4 9.1 2.1 1 1 0 1 1 1 1 Man1-Src1p-C-terminal domain C1_2 PF03107.16 OQS06484.1 - 0.0039 17.5 0.7 0.0039 17.5 0.7 2.3 2 0 0 2 2 2 1 C1 domain Zf_RING PF16744.5 OQS06484.1 - 0.88 9.7 6.0 0.41 10.8 3.4 1.8 2 0 0 2 2 2 0 KIAA1045 RING finger Zip PF02535.22 OQS06485.1 - 1.2e-29 103.6 11.8 3.1e-29 102.3 11.8 1.6 1 1 0 1 1 1 1 ZIP Zinc transporter Cu-oxidase_2 PF07731.14 OQS06485.1 - 3.6e-11 43.0 2.2 2.1e-10 40.5 2.2 2.2 1 1 0 1 1 1 1 Multicopper oxidase Cu-oxidase_3 PF07732.15 OQS06485.1 - 1.6e-08 34.6 4.5 9.3e-08 32.1 0.2 2.7 3 0 0 3 3 3 1 Multicopper oxidase EamA PF00892.20 OQS06486.1 - 1.1e-21 77.4 35.4 2.4e-13 50.4 13.7 3.2 3 0 0 3 3 3 2 EamA-like transporter family CorA PF01544.18 OQS06486.1 - 7e-20 71.5 19.0 1.3e-10 41.1 5.4 3.0 2 1 0 2 2 2 2 CorA-like Mg2+ transporter protein TMEM70 PF06979.12 OQS06486.1 - 2.7e-07 31.1 0.0 2.7e-07 31.1 0.0 2.9 4 0 0 4 4 4 1 Assembly, mitochondrial proton-transport ATP synth complex Proton_antipo_C PF01010.19 OQS06486.1 - 0.72 9.4 7.6 5.5 6.5 0.9 3.1 3 0 0 3 3 3 0 NADH-dehyrogenase subunit F, TMs, (complex I) C-terminus Tetraspanin PF00335.20 OQS06487.1 - 1.8e-11 44.2 12.4 2.4e-11 43.8 12.4 1.1 1 0 0 1 1 1 1 Tetraspanin family ECF_trnsprt PF12822.7 OQS06487.1 - 0.017 15.3 5.2 0.029 14.5 5.2 1.3 1 0 0 1 1 1 0 ECF transporter, substrate-specific component Ank_5 PF13857.6 OQS06488.1 - 0.00067 19.9 0.0 0.017 15.5 0.0 2.1 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 OQS06488.1 - 0.0017 18.9 0.0 0.002 18.7 0.0 1.2 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQS06488.1 - 0.023 15.3 0.0 3.6 8.3 0.0 2.1 2 0 0 2 2 2 0 Ankyrin repeats (many copies) Cyclin_N PF00134.23 OQS06489.1 - 1.1e-17 64.0 0.1 2.6e-17 62.8 0.0 1.6 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 OQS06489.1 - 2.7e-12 46.8 1.3 6.7e-12 45.5 0.2 2.1 2 1 1 3 3 3 1 Cyclin, C-terminal domain A_thal_3526 PF09713.10 OQS06490.1 - 2e-25 88.8 1.0 3.6e-25 88.0 1.0 1.4 1 0 0 1 1 1 1 Plant protein 1589 of unknown function (A_thal_3526) PAN_3 PF08277.12 OQS06490.1 - 0.085 12.7 0.0 0.18 11.7 0.0 1.5 1 0 0 1 1 1 0 PAN-like domain DUF2773 PF10971.8 OQS06490.1 - 0.14 12.3 0.1 0.52 10.5 0.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2773) QLQ PF08880.11 OQS06490.1 - 8.9 6.2 6.6 0.49 10.2 0.4 2.1 3 0 0 3 3 3 0 QLQ SlyX PF04102.12 OQS06491.1 - 0.0098 16.5 0.0 0.0098 16.5 0.0 1.9 2 0 0 2 2 2 1 SlyX Caskin1-CID PF16600.5 OQS06491.1 - 4.5 7.9 6.7 11 6.7 1.4 2.7 2 0 0 2 2 2 0 Caskin1 CASK-interaction domain BBS1 PF14779.6 OQS06492.1 - 1.2e-96 323.0 0.1 8.9e-96 320.2 0.1 2.0 2 0 0 2 2 2 1 Ciliary BBSome complex subunit 1 BBS2_Mid PF14783.6 OQS06492.1 - 4.7e-06 26.6 0.0 0.34 11.0 0.0 3.4 2 1 2 4 4 4 3 Ciliary BBSome complex subunit 2, middle region DUF1640 PF07798.11 OQS06493.1 - 0.013 15.6 2.1 0.013 15.6 2.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1640) DUF3150 PF11348.8 OQS06493.1 - 0.015 14.5 2.7 0.15 11.3 0.4 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3150) ABC_tran_CTD PF16326.5 OQS06493.1 - 0.079 13.2 13.7 0.038 14.2 3.0 2.8 2 1 0 2 2 2 0 ABC transporter C-terminal domain zf-B_box PF00643.24 OQS06493.1 - 0.091 12.9 32.6 0.066 13.4 16.3 2.4 2 0 0 2 2 2 0 B-box zinc finger T7SS_ESX_EspC PF10824.8 OQS06493.1 - 0.33 11.5 3.2 5.3 7.6 0.7 2.8 3 0 0 3 3 3 0 Excreted virulence factor EspC, type VII ESX diderm DUF4407 PF14362.6 OQS06493.1 - 1.3 8.4 7.9 3.9 6.7 7.9 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Baculo_PEP_C PF04513.12 OQS06493.1 - 3.5 7.7 7.5 3.9 7.5 2.4 2.4 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF5446 PF17522.2 OQS06493.1 - 6.5 7.0 8.5 5 7.4 1.1 3.0 2 1 1 3 3 3 0 Family of unknown function (DUF5446) Ank_4 PF13637.6 OQS06494.1 - 3.3e-17 62.6 0.0 8.4e-14 51.7 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 OQS06494.1 - 3.9e-17 62.6 0.1 7.3e-17 61.7 0.1 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) EF-hand_1 PF00036.32 OQS06494.1 - 6.3e-17 59.8 4.8 1.1e-06 27.8 0.1 3.8 3 0 0 3 3 3 2 EF hand EF-hand_7 PF13499.6 OQS06494.1 - 1.2e-15 57.7 1.2 1.2e-14 54.5 0.2 2.5 2 0 0 2 2 2 1 EF-hand domain pair Ank_5 PF13857.6 OQS06494.1 - 3.8e-15 55.8 0.3 1e-06 28.9 0.2 3.4 1 1 2 3 3 3 3 Ankyrin repeats (many copies) EF-hand_6 PF13405.6 OQS06494.1 - 7.8e-14 50.4 3.9 1.1e-05 25.0 0.1 4.0 2 1 2 4 4 4 2 EF-hand domain EF-hand_5 PF13202.6 OQS06494.1 - 1.3e-13 49.8 6.9 3.4e-06 26.3 0.1 3.6 3 0 0 3 3 3 2 EF hand Ank PF00023.30 OQS06494.1 - 2.8e-13 49.6 0.1 0.00012 22.4 0.4 3.5 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.6 OQS06494.1 - 1.4e-12 46.6 0.1 0.00036 20.7 0.1 3.5 3 0 0 3 3 3 2 Ankyrin repeat EF-hand_8 PF13833.6 OQS06494.1 - 2.2e-12 46.6 5.2 2.5e-06 27.2 0.1 2.9 2 1 1 3 3 3 2 EF-hand domain pair fn3 PF00041.21 OQS06494.1 - 8.9e-08 32.4 0.0 1.8e-07 31.4 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III domain AAA_6 PF12774.7 OQS06495.1 - 2.1e-141 470.7 0.1 4.3e-140 466.3 0.1 2.8 2 1 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 OQS06495.1 - 2.7e-128 428.4 4.1 2.7e-128 428.4 4.1 2.7 3 0 0 3 3 3 1 Dynein heavy chain, N-terminal region 2 Dynein_C PF18199.1 OQS06495.1 - 2.4e-110 368.6 0.0 1.7e-109 365.8 0.0 2.4 2 0 0 2 2 2 1 Dynein heavy chain C-terminal domain AAA_8 PF12780.7 OQS06495.1 - 1.3e-101 339.4 0.6 1.7e-100 335.6 0.0 2.8 3 0 0 3 3 3 1 P-loop containing dynein motor region D4 AAA_9 PF12781.7 OQS06495.1 - 1.1e-93 312.4 0.6 3.9e-91 304.1 1.4 2.8 2 0 0 2 2 2 1 ATP-binding dynein motor region AAA_7 PF12775.7 OQS06495.1 - 4.2e-76 254.5 0.0 1.5e-75 252.7 0.0 2.1 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_lid_11 PF18198.1 OQS06495.1 - 1.3e-58 197.4 0.0 4.9e-58 195.6 0.0 2.1 2 0 0 2 2 2 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 OQS06495.1 - 1.6e-45 154.1 0.0 6.9e-44 148.8 0.0 2.9 2 0 0 2 2 2 1 Dynein heavy chain region D6 P-loop domain MT PF12777.7 OQS06495.1 - 5.2e-40 137.5 7.8 1.2e-39 136.3 7.8 1.6 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor Dynein_AAA_lid PF17852.1 OQS06495.1 - 5.3e-28 97.7 1.4 1.7e-27 96.0 0.0 2.7 3 0 0 3 3 2 1 Dynein heavy chain AAA lid domain AAA_lid_1 PF17857.1 OQS06495.1 - 1.2e-16 60.7 0.2 9.1e-16 57.9 0.2 2.5 2 0 0 2 2 2 1 AAA+ lid domain AAA_5 PF07728.14 OQS06495.1 - 1.6e-12 47.6 0.0 0.00073 19.5 0.0 5.5 4 1 0 4 4 4 2 AAA domain (dynein-related subfamily) AAA_30 PF13604.6 OQS06495.1 - 3.6e-05 23.6 0.0 0.00054 19.7 0.0 2.6 2 0 0 2 2 2 1 AAA domain T2SSE PF00437.20 OQS06495.1 - 5.2e-05 22.4 0.0 0.00034 19.8 0.0 2.4 3 0 0 3 3 2 1 Type II/IV secretion system protein AAA PF00004.29 OQS06495.1 - 0.0004 20.8 0.1 0.31 11.5 0.0 4.0 4 0 0 4 4 3 1 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.6 OQS06495.1 - 0.0065 16.2 0.0 0.088 12.6 0.0 2.7 3 0 0 3 3 2 1 P-loop containing region of AAA domain Roc PF08477.13 OQS06495.1 - 0.0089 16.2 0.0 0.028 14.6 0.0 1.9 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Plasmid_RAQPRD PF09686.10 OQS06495.1 - 0.048 13.9 0.0 1.1 9.5 0.0 3.4 2 1 0 2 2 2 0 Plasmid protein of unknown function (Plasmid_RAQPRD) IstB_IS21 PF01695.17 OQS06495.1 - 0.085 12.6 0.0 0.26 11.0 0.0 1.8 1 0 0 1 1 1 0 IstB-like ATP binding protein Sigma54_activat PF00158.26 OQS06495.1 - 0.088 12.5 0.0 0.24 11.1 0.0 1.7 1 0 0 1 1 1 0 Sigma-54 interaction domain SKA2 PF16740.5 OQS06495.1 - 0.1 12.4 1.5 6 6.7 0.3 3.2 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 2 ABC_tran PF00005.27 OQS06495.1 - 0.15 12.5 0.0 2.1 8.9 0.0 2.9 2 0 0 2 2 2 0 ABC transporter AAA_22 PF13401.6 OQS06495.1 - 0.16 12.2 0.1 1.2 9.4 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.6 OQS06495.1 - 0.91 9.9 4.6 1.5 9.2 0.0 3.4 4 0 0 4 4 3 0 AAA domain Snapin_Pallidin PF14712.6 OQS06495.1 - 1.9 9.0 10.4 6.8 7.2 0.4 3.8 3 0 0 3 3 2 0 Snapin/Pallidin DUF1090 PF06476.12 OQS06495.1 - 4.4 7.5 7.1 0.62 10.2 1.2 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1090) DUF5082 PF16888.5 OQS06495.1 - 6.4 7.1 9.4 3.4 8.0 0.8 3.6 2 1 1 3 3 3 0 Domain of unknown function (DUF5082) DUF5401 PF17380.2 OQS06495.1 - 7 4.6 10.0 0.058 11.5 0.1 2.1 2 0 0 2 2 1 0 Family of unknown function (DUF5401) TBCC_N PF16752.5 OQS06495.1 - 8.5 6.9 8.5 1.5 9.3 1.7 3.2 2 0 0 2 2 2 0 Tubulin-specific chaperone C N-terminal domain HTH_Tnp_Tc5 PF03221.16 OQS06496.1 - 1.6e-06 28.1 0.2 4.1e-06 26.7 0.2 1.7 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain Ank_5 PF13857.6 OQS06497.1 - 2.5e-23 81.8 1.2 5e-10 39.4 0.0 4.5 3 1 1 4 4 4 4 Ankyrin repeats (many copies) Ank_4 PF13637.6 OQS06497.1 - 4.2e-19 68.6 0.5 8.5e-06 26.2 0.0 5.1 3 1 1 4 4 4 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 OQS06497.1 - 4.5e-19 68.8 0.8 4e-09 36.9 0.1 3.3 3 0 0 3 3 3 2 Ankyrin repeats (3 copies) Ank PF00023.30 OQS06497.1 - 4.4e-17 61.7 2.1 5.1e-05 23.5 0.4 4.9 6 0 0 6 6 6 3 Ankyrin repeat Ank_3 PF13606.6 OQS06497.1 - 7.9e-15 53.5 1.4 2.5e-05 24.3 0.0 4.8 5 0 0 5 5 5 2 Ankyrin repeat LRR_8 PF13855.6 OQS06498.1 - 1.8e-36 123.7 35.0 3e-09 36.5 1.9 5.7 3 1 4 7 7 7 6 Leucine rich repeat DUF3336 PF11815.8 OQS06498.1 - 3.1e-27 95.0 0.0 2.9e-26 91.9 0.0 2.4 2 1 0 2 2 2 1 Domain of unknown function (DUF3336) LRR_4 PF12799.7 OQS06498.1 - 1.2e-26 92.3 18.6 1.6e-05 25.1 0.3 6.8 3 2 5 8 8 8 8 Leucine Rich repeats (2 copies) Patatin PF01734.22 OQS06498.1 - 1.3e-19 71.2 0.0 3e-19 70.0 0.0 1.6 1 0 0 1 1 1 1 Patatin-like phospholipase LRR_9 PF14580.6 OQS06498.1 - 3.7e-09 36.3 9.1 0.0006 19.4 0.1 3.5 1 1 1 3 3 3 3 Leucine-rich repeat LRR_1 PF00560.33 OQS06498.1 - 0.00037 20.6 20.9 23 6.1 0.1 9.9 10 1 1 11 11 11 1 Leucine Rich Repeat DUF3821 PF12863.7 OQS06498.1 - 0.023 14.6 0.0 0.039 13.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3821) SecE PF00584.20 OQS06499.1 - 2.2e-15 56.3 0.1 2.5e-15 56.1 0.1 1.1 1 0 0 1 1 1 1 SecE/Sec61-gamma subunits of protein translocation complex Ank_4 PF13637.6 OQS06500.1 - 3.2e-14 53.1 3.6 3.5e-05 24.3 0.0 3.9 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 OQS06500.1 - 4.7e-14 52.7 6.3 3.3e-06 27.6 0.0 3.1 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OQS06500.1 - 2e-09 37.5 1.2 0.05 13.9 0.1 4.7 1 1 4 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQS06500.1 - 5.1e-06 26.4 1.5 3.8 8.4 0.0 4.9 5 0 0 5 5 5 1 Ankyrin repeat DUF5049 PF16468.5 OQS06500.1 - 0.00077 19.3 4.4 12 5.9 0.0 4.9 4 1 1 5 5 5 2 Domain of unknown function (DUF5049) Ank PF00023.30 OQS06500.1 - 0.003 18.0 0.3 17 6.1 0.0 4.4 1 1 1 2 2 2 1 Ankyrin repeat SDF PF00375.18 OQS06501.1 - 7.9e-95 318.1 38.1 9e-95 318.0 38.1 1.0 1 0 0 1 1 1 1 Sodium:dicarboxylate symporter family Ank_2 PF12796.7 OQS06502.1 - 3.2e-226 732.6 75.7 6.9e-18 65.0 0.1 16.7 3 3 16 20 20 20 20 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQS06502.1 - 9.9e-155 501.1 44.9 3e-09 37.2 0.0 25.5 7 6 22 29 29 29 28 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQS06502.1 - 2.4e-145 454.5 32.2 0.00014 22.0 0.0 34.5 35 0 0 35 35 35 32 Ankyrin repeat Ank PF00023.30 OQS06502.1 - 1.9e-140 451.8 67.6 1.2e-05 25.5 0.1 35.2 34 2 2 36 36 36 30 Ankyrin repeat Ank_5 PF13857.6 OQS06502.1 - 7.9e-128 414.8 54.7 3.2e-08 33.7 0.0 25.8 6 3 21 29 29 29 28 Ankyrin repeats (many copies) PsbJ PF01788.17 OQS06502.1 - 0.00015 21.6 2.4 11 5.9 0.0 6.9 8 0 0 8 8 8 1 PsbJ PEGA PF08308.11 OQS06502.1 - 0.001 18.9 0.2 34 4.4 0.0 7.5 10 0 0 10 10 10 0 PEGA domain Cyclin_N PF00134.23 OQS06502.1 - 0.052 13.3 1.1 1.9 8.2 0.0 4.0 4 1 1 5 5 5 0 Cyclin, N-terminal domain DUF1593 PF07632.11 OQS06502.1 - 0.2 11.1 0.8 5.8 6.3 0.0 3.9 5 0 0 5 5 5 0 Protein of unknown function (DUF1593) LVIVD PF08309.11 OQS06502.1 - 0.39 10.1 2.8 1.3 8.4 0.0 3.6 3 0 0 3 3 3 0 LVIVD repeat UBM PF14377.6 OQS06504.1 - 0.13 11.7 0.0 0.29 10.6 0.0 1.6 1 0 0 1 1 1 0 Ubiquitin binding region Sec20 PF03908.13 OQS06506.1 - 7.9e-12 44.9 0.4 3.2e-11 43.0 0.4 2.1 1 0 0 1 1 1 1 Sec20 DUF4633 PF15464.6 OQS06506.1 - 3.8 7.7 7.3 1.1 9.4 0.0 3.5 4 0 0 4 4 4 0 Domain of unknown function (DUF4633) Copine PF07002.16 OQS06507.1 - 2.7e-56 190.5 0.1 4.3e-56 189.8 0.1 1.3 1 0 0 1 1 1 1 Copine FYVE PF01363.21 OQS06507.1 - 4.8e-16 58.6 26.4 1.5e-10 41.0 9.9 4.6 3 1 1 4 4 4 2 FYVE zinc finger zf-C3HC4_2 PF13923.6 OQS06507.1 - 1e-05 25.3 13.2 1e-05 25.3 13.2 6.1 6 1 1 7 7 7 1 Zinc finger, C3HC4 type (RING finger) GAF PF01590.26 OQS06507.1 - 0.00022 21.9 0.0 0.00069 20.2 0.0 1.8 1 0 0 1 1 1 1 GAF domain zf-RanBP PF00641.18 OQS06507.1 - 0.00082 18.6 2.9 0.00082 18.6 2.9 4.5 5 0 0 5 5 5 1 Zn-finger in Ran binding protein and others vWA-TerF-like PF10138.9 OQS06507.1 - 0.00098 19.3 1.7 0.0039 17.3 1.7 1.9 1 1 0 1 1 1 1 vWA found in TerF C terminus zf-C3HC4 PF00097.25 OQS06507.1 - 0.0047 16.8 12.8 0.0047 16.8 12.8 5.3 5 2 1 6 6 6 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 OQS06507.1 - 0.0073 16.6 11.7 0.0073 16.6 11.7 5.9 5 1 1 6 6 6 1 Ring finger domain Rad50_zn_hook PF04423.14 OQS06507.1 - 8.2 6.3 9.7 12 5.9 4.2 3.2 3 0 0 3 3 3 0 Rad50 zinc hook motif zf-C4H2 PF10146.9 OQS06508.1 - 0.02 15.2 0.5 0.031 14.6 0.5 1.3 1 0 0 1 1 1 0 Zinc finger-containing protein PRIMA1 PF16101.5 OQS06508.1 - 0.1 12.7 7.3 0.17 11.9 7.3 1.3 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 Oxidored_q3 PF00499.20 OQS06508.1 - 0.12 12.1 0.0 0.34 10.6 0.0 1.7 2 0 0 2 2 2 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 NTF2 PF02136.20 OQS06509.1 - 2.7e-25 89.2 0.0 4.7e-25 88.5 0.0 1.4 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain RRM_1 PF00076.22 OQS06509.1 - 4.5e-10 39.2 0.0 8.1e-10 38.4 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4518 PF15008.6 OQS06509.1 - 0.043 13.0 0.0 0.073 12.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4518) RNA_bind PF08675.11 OQS06509.1 - 0.098 12.7 0.0 0.18 11.9 0.0 1.3 1 0 0 1 1 1 0 RNA binding domain Glypican PF01153.19 OQS06509.1 - 1.4 7.7 3.1 2.2 7.0 0.0 2.2 2 0 0 2 2 2 0 Glypican CxxCxxCC PF03692.15 OQS06510.1 - 1.5e-14 54.4 1.6 3e-14 53.5 1.6 1.5 1 0 0 1 1 1 1 Putative zinc- or iron-chelating domain Methyltransf_31 PF13847.6 OQS06510.1 - 0.04 13.7 0.0 0.088 12.6 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain MgtE_N PF03448.17 OQS06510.1 - 0.041 14.5 0.3 0.096 13.3 0.3 1.6 1 0 0 1 1 1 0 MgtE intracellular N domain Mst1_SARAH PF11629.8 OQS06510.1 - 0.18 11.9 0.6 0.39 10.8 0.6 1.5 1 0 0 1 1 1 0 C terminal SARAH domain of Mst1 PDZ_6 PF17820.1 OQS06511.1 - 0.0016 18.2 0.0 2.1 8.2 0.0 2.7 2 1 0 2 2 2 2 PDZ domain RecR PF02132.15 OQS06511.1 - 0.029 13.9 0.0 0.057 13.0 0.0 1.4 1 0 0 1 1 1 0 RecR protein DUF1482 PF07358.11 OQS06511.1 - 0.13 12.2 0.0 0.32 10.9 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1482) DUF3090 PF11290.8 OQS06512.1 - 0.056 13.3 0.4 0.065 13.0 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3090) Alpha_kinase PF02816.18 OQS06513.1 - 2.6e-56 190.7 0.1 4.3e-56 190.0 0.1 1.4 1 0 0 1 1 1 1 Alpha-kinase family SHOCT PF09851.9 OQS06513.1 - 3.1e-06 26.7 0.3 6.2e-06 25.8 0.3 1.5 1 0 0 1 1 1 1 Short C-terminal domain GvpG PF05120.12 OQS06513.1 - 0.023 14.7 0.1 0.073 13.1 0.0 1.9 2 0 0 2 2 2 0 Gas vesicle protein G PPR_2 PF13041.6 OQS06514.1 - 1.6e-07 31.4 1.9 0.13 12.5 0.0 4.6 4 1 1 5 5 5 2 PPR repeat family PPR PF01535.20 OQS06514.1 - 1.8e-07 31.0 0.0 0.15 12.4 0.0 4.5 4 0 0 4 4 4 2 PPR repeat PPR_long PF17177.4 OQS06514.1 - 2.1e-07 30.6 1.3 0.0085 15.5 0.0 2.8 1 1 2 3 3 3 2 Pentacotripeptide-repeat region of PRORP TPR_19 PF14559.6 OQS06514.1 - 3.1e-06 27.6 4.8 0.04 14.4 0.4 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat PPR_3 PF13812.6 OQS06514.1 - 4.2e-05 23.5 0.1 0.0028 17.7 0.1 2.6 1 1 1 2 2 2 2 Pentatricopeptide repeat domain DUF4611 PF15387.6 OQS06514.1 - 0.0083 16.3 6.4 0.015 15.5 6.4 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4611) PPR_1 PF12854.7 OQS06514.1 - 0.044 13.5 0.0 23 4.8 0.0 3.3 4 0 0 4 4 4 0 PPR repeat Clathrin PF00637.20 OQS06514.1 - 2.5 8.0 6.8 15 5.5 0.4 3.2 1 1 1 3 3 3 0 Region in Clathrin and VPS Cwf_Cwc_15 PF04889.12 OQS06514.1 - 4.5 6.9 10.1 6.6 6.4 10.1 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Pro_isomerase PF00160.21 OQS06516.1 - 2.7e-39 135.0 0.0 6.4e-39 133.8 0.0 1.6 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RNase_HII PF01351.18 OQS06516.1 - 3.7e-36 124.8 0.2 8.1e-36 123.7 0.2 1.5 1 0 0 1 1 1 1 Ribonuclease HII IFT57 PF10498.9 OQS06516.1 - 5.1e-23 81.6 4.9 3.5e-22 78.9 0.0 2.4 2 0 0 2 2 2 1 Intra-flagellar transport protein 57 Pkinase PF00069.25 OQS06516.1 - 3.6e-17 62.6 0.1 7.1e-17 61.6 0.1 1.5 1 0 0 1 1 1 1 Protein kinase domain COPI_assoc PF08507.10 OQS06516.1 - 4.3e-16 59.2 30.7 8e-08 32.4 13.9 2.6 2 0 0 2 2 2 2 COPI associated protein EF-hand_7 PF13499.6 OQS06516.1 - 1.7e-12 47.6 7.1 3.5e-07 30.6 0.7 2.7 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 OQS06516.1 - 1.2e-11 43.5 5.3 0.0068 16.2 0.1 4.6 4 0 0 4 4 4 4 EF-hand domain Pkinase_Tyr PF07714.17 OQS06516.1 - 1.4e-11 44.1 0.1 2.6e-11 43.3 0.1 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase EF-hand_1 PF00036.32 OQS06516.1 - 2.4e-11 42.4 3.9 0.0035 16.8 0.2 4.5 4 0 0 4 4 4 3 EF hand EF-hand_5 PF13202.6 OQS06516.1 - 4.7e-08 32.2 0.5 0.015 14.7 0.3 3.5 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.6 OQS06516.1 - 4.3e-05 23.3 8.1 0.028 14.3 0.2 3.8 2 2 1 3 3 3 2 EF-hand domain pair GED PF02212.18 OQS06517.1 - 0.08 13.1 0.0 0.22 11.7 0.0 1.8 1 0 0 1 1 1 0 Dynamin GTPase effector domain AA_kinase PF00696.28 OQS06518.1 - 5.6e-38 130.9 2.4 9.4e-38 130.2 2.4 1.4 1 0 0 1 1 1 1 Amino acid kinase family Aldedh PF00171.22 OQS06518.1 - 2.4e-15 56.0 0.2 4e-10 38.8 0.0 2.4 2 1 0 2 2 2 2 Aldehyde dehydrogenase family DUF773 PF05600.12 OQS06519.1 - 6.1e-101 338.7 14.0 7.8e-101 338.3 14.0 1.0 1 0 0 1 1 1 1 CDK5 regulatory subunit-associated protein 3 CLZ PF16526.5 OQS06519.1 - 0.013 15.9 0.3 0.056 13.8 0.3 2.3 1 0 0 1 1 1 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels FapA PF03961.13 OQS06519.1 - 0.078 11.6 10.9 0.35 9.4 0.2 2.2 2 0 0 2 2 2 0 Flagellar Assembly Protein A Sigma70_ner PF04546.13 OQS06519.1 - 1.4 8.7 7.2 0.36 10.7 2.8 2.3 2 1 0 2 2 2 0 Sigma-70, non-essential region DUF2570 PF10828.8 OQS06519.1 - 6.2 6.7 9.0 3.4 7.5 3.1 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2570) PRKG1_interact PF15898.5 OQS06519.1 - 7.2 7.6 9.2 11 7.0 5.0 3.2 2 1 0 2 2 2 0 cGMP-dependent protein kinase interacting domain XhlA PF10779.9 OQS06519.1 - 7.6 6.8 9.2 0.83 9.9 1.8 2.9 2 1 1 3 3 3 0 Haemolysin XhlA HrpB7 PF09486.10 OQS06519.1 - 9.8 6.5 7.1 4.3 7.7 3.1 2.1 2 0 0 2 2 2 0 Bacterial type III secretion protein (HrpB7) Glycos_transf_1 PF00534.20 OQS06520.1 - 8.6e-37 126.3 0.0 1.4e-36 125.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 OQS06520.1 - 1.5e-18 67.6 0.0 2.3e-18 66.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 OQS06520.1 - 9.1e-14 51.8 0.1 1.5e-13 51.1 0.1 1.4 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_1_2 PF13524.6 OQS06520.1 - 1.5e-08 34.9 0.0 3.6e-08 33.7 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 OQS06520.1 - 6.1e-05 23.5 0.0 0.00011 22.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain PRAI PF00697.22 OQS06520.1 - 0.028 14.2 0.0 0.052 13.3 0.0 1.4 1 0 0 1 1 1 0 N-(5'phosphoribosyl)anthranilate (PRA) isomerase RhoGAP-FF1 PF16512.5 OQS06520.1 - 0.047 14.4 0.0 0.11 13.2 0.0 1.5 1 0 0 1 1 1 0 p190-A and -B Rho GAPs FF domain EF-hand_4 PF12763.7 OQS06521.1 - 4.6e-19 68.3 0.0 4.4e-11 42.7 0.0 2.3 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand EF-hand_7 PF13499.6 OQS06521.1 - 1.3e-08 35.2 0.3 2.3e-06 27.9 0.1 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 OQS06521.1 - 5e-06 25.7 0.0 0.26 10.9 0.0 3.4 4 0 0 4 4 4 2 EF hand EF-hand_6 PF13405.6 OQS06521.1 - 1e-05 25.0 0.3 0.76 9.9 0.0 3.6 3 0 0 3 3 3 2 EF-hand domain EF-hand_5 PF13202.6 OQS06521.1 - 0.047 13.2 0.1 4.3 7.0 0.1 2.5 2 0 0 2 2 2 0 EF hand MFS_1 PF07690.16 OQS06522.1 - 8.2e-11 41.4 16.2 8.2e-11 41.4 16.2 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily HhH-GPD PF00730.25 OQS06523.1 - 4.5e-23 81.8 0.0 9.3e-23 80.7 0.0 1.6 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 OQS06523.1 - 8.4e-08 31.7 0.0 3e-07 30.0 0.0 2.0 2 0 0 2 2 2 1 Helix-hairpin-helix motif HHH_5 PF14520.6 OQS06523.1 - 0.0054 17.3 0.0 0.22 12.1 0.0 2.5 2 0 0 2 2 2 1 Helix-hairpin-helix domain Histone_HNS PF00816.21 OQS06523.1 - 0.18 12.6 4.4 20 6.1 2.5 2.6 2 0 0 2 2 2 0 H-NS histone family EndIII_4Fe-2S PF10576.9 OQS06523.1 - 0.32 11.4 3.6 0.6 10.5 3.6 1.5 1 0 0 1 1 1 0 Iron-sulfur binding domain of endonuclease III PAP2_C PF14360.6 OQS06524.1 - 3e-08 34.1 4.7 3e-08 34.1 4.7 2.2 3 0 0 3 3 3 1 PAP2 superfamily C-terminal PAP2 PF01569.21 OQS06524.1 - 0.00092 19.0 3.4 0.00092 19.0 3.4 1.9 2 1 0 2 2 2 1 PAP2 superfamily PAP2_3 PF14378.6 OQS06524.1 - 0.00094 18.9 11.3 0.008 15.9 11.3 2.2 1 1 0 1 1 1 1 PAP2 superfamily DUF2304 PF10066.9 OQS06524.1 - 0.63 10.3 0.0 0.63 10.3 0.0 2.6 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2304) RNB PF00773.19 OQS06525.1 - 2e-89 300.2 0.0 2.9e-89 299.6 0.0 1.3 1 0 0 1 1 1 1 RNB domain OB_Dis3 PF17849.1 OQS06525.1 - 5.7e-16 58.3 0.0 1.4e-15 57.0 0.0 1.8 1 0 0 1 1 1 1 Dis3-like cold-shock domain 2 (CSD2) Rrp44_CSD1 PF17216.3 OQS06525.1 - 2e-08 34.1 0.0 4.3e-08 33.0 0.0 1.4 1 0 0 1 1 1 1 Rrp44-like cold shock domain OB_RNB PF08206.11 OQS06525.1 - 0.00086 18.9 0.0 0.0025 17.5 0.0 1.7 1 0 0 1 1 1 1 Ribonuclease B OB domain Rrp44_S1 PF17215.3 OQS06525.1 - 0.023 14.6 0.0 0.056 13.4 0.0 1.6 1 0 0 1 1 1 0 S1 domain DUF1442 PF07279.11 OQS06526.1 - 0.0075 15.6 0.1 2.1 7.6 0.1 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF1442) Apo-CIII PF05778.12 OQS06526.1 - 0.0088 15.7 0.2 0.037 13.7 0.0 2.0 2 0 0 2 2 2 1 Apolipoprotein CIII (Apo-CIII) DUF3725 PF12523.8 OQS06526.1 - 0.077 13.3 0.1 0.88 9.9 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3725) DUF5053 PF16476.5 OQS06526.1 - 0.079 12.6 0.2 0.32 10.7 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF5053) DUF1542 PF07564.11 OQS06526.1 - 1.7 8.8 6.0 1.3 9.2 1.5 2.6 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1542) TPR_12 PF13424.6 OQS06527.1 - 1.3e-23 83.1 13.3 8.2e-10 38.8 0.2 5.3 4 1 1 5 5 5 4 Tetratricopeptide repeat Ank_4 PF13637.6 OQS06527.1 - 5e-16 58.8 0.8 1.1e-11 45.0 0.2 4.0 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 OQS06527.1 - 5.6e-16 58.4 1.1 4.6e-08 33.2 0.1 3.0 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 OQS06527.1 - 6.9e-16 58.6 0.3 4.1e-07 30.5 0.0 2.8 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OQS06527.1 - 1.7e-12 46.3 0.4 0.00044 20.5 0.0 4.8 4 0 0 4 4 4 2 Ankyrin repeat Ank PF00023.30 OQS06527.1 - 7.8e-12 45.1 1.4 0.00011 22.5 0.0 4.2 3 1 1 4 4 4 2 Ankyrin repeat TPR_10 PF13374.6 OQS06527.1 - 1.9e-05 24.4 17.1 0.48 10.4 0.0 7.0 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_8 PF13181.6 OQS06527.1 - 0.00021 21.3 7.7 0.84 10.0 0.1 4.8 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_1 PF00515.28 OQS06527.1 - 0.00041 20.1 17.8 0.019 14.8 0.2 5.7 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_2 PF07719.17 OQS06527.1 - 0.00051 20.0 18.6 0.0093 16.0 0.3 5.8 6 1 0 7 7 6 2 Tetratricopeptide repeat TPR_6 PF13174.6 OQS06527.1 - 0.0069 16.9 6.5 4.5 8.1 0.0 4.7 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.6 OQS06527.1 - 0.0074 17.0 4.1 16 6.6 0.1 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat BLM10_mid PF16507.5 OQS06527.1 - 0.011 14.4 0.4 0.017 13.8 0.4 1.2 1 0 0 1 1 1 0 Proteasome-substrate-size regulator, mid region TPR_7 PF13176.6 OQS06527.1 - 0.2 11.7 4.4 0.31 11.2 0.1 3.5 4 0 0 4 4 3 0 Tetratricopeptide repeat zf-ZPR1 PF03367.13 OQS06528.1 - 1.2e-106 353.4 0.0 1.1e-55 187.9 0.1 2.8 2 0 0 2 2 2 2 ZPR1 zinc-finger domain Kinesin PF00225.23 OQS06528.1 - 6.2e-36 124.0 0.1 2.3e-35 122.1 0.1 1.8 1 1 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 OQS06528.1 - 2.1e-10 40.7 0.0 4.7e-10 39.6 0.0 1.6 1 0 0 1 1 1 1 Microtubule binding F-box-like PF12937.7 OQS06528.1 - 1.3e-05 25.0 0.3 3.3e-05 23.7 0.3 1.7 1 0 0 1 1 1 1 F-box-like HHH_3 PF12836.7 OQS06528.1 - 0.0015 18.8 0.0 0.019 15.2 0.0 2.4 2 0 0 2 2 2 1 Helix-hairpin-helix motif DUF655 PF04919.12 OQS06528.1 - 0.029 14.3 0.0 0.072 13.0 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF655) cNMP_binding PF00027.29 OQS06529.1 - 2.7e-29 101.1 0.0 2e-09 37.4 0.0 4.0 4 0 0 4 4 4 3 Cyclic nucleotide-binding domain Ion_trans_2 PF07885.16 OQS06529.1 - 5.7e-05 23.0 17.1 0.00013 21.9 4.6 4.4 3 0 0 3 3 3 2 Ion channel 2OG-FeII_Oxy_3 PF13640.6 OQS06530.1 - 1.1e-07 32.7 0.0 0.003 18.4 0.0 2.5 2 0 0 2 2 2 2 2OG-Fe(II) oxygenase superfamily DHHC PF01529.20 OQS06531.1 - 1.4e-34 119.1 10.5 1.4e-34 119.1 10.5 2.1 2 0 0 2 2 2 1 DHHC palmitoyltransferase IGFBP PF00219.18 OQS06531.1 - 0.67 10.7 6.4 1.9 9.2 6.4 1.7 1 0 0 1 1 1 0 Insulin-like growth factor binding protein WD40 PF00400.32 OQS06532.1 - 1.7e-11 44.4 10.3 1.3 10.0 0.1 7.0 6 0 0 6 6 6 4 WD domain, G-beta repeat Sec16_C PF12931.7 OQS06532.1 - 7.6e-07 29.1 3.4 1.2e-05 25.2 3.4 2.4 1 1 0 1 1 1 1 Sec23-binding domain of Sec16 ANAPC4_WD40 PF12894.7 OQS06532.1 - 8.4e-06 26.0 0.0 0.018 15.3 0.0 3.8 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain DUF3432 PF11914.8 OQS06532.1 - 0.0058 16.9 20.0 0.0058 16.9 20.0 5.5 1 1 5 6 6 6 1 Domain of unknown function (DUF3432) Sec16 PF12932.7 OQS06532.1 - 0.006 17.2 0.7 0.13 12.8 0.1 3.1 3 1 1 4 4 4 1 Vesicle coat trafficking protein Sec16 mid-region IML1 PF12257.8 OQS06533.1 - 2.6e-88 295.8 0.1 4.9e-88 295.0 0.0 1.5 2 0 0 2 2 2 1 Vacuolar membrane-associated protein Iml1 GCP_C_terminal PF04130.13 OQS06534.1 - 1.2e-81 274.5 9.2 1.9e-81 273.9 9.2 1.3 1 0 0 1 1 1 1 Gamma tubulin complex component C-terminal GCP_N_terminal PF17681.1 OQS06534.1 - 1.9e-73 247.8 0.2 3.3e-73 247.0 0.2 1.4 1 0 0 1 1 1 1 Gamma tubulin complex component N-terminal Rhomboid PF01694.22 OQS06535.1 - 1.7e-19 70.3 6.1 2.7e-19 69.6 6.1 1.3 1 0 0 1 1 1 1 Rhomboid family Flavin_Reduct PF01613.18 OQS06535.1 - 6.5e-11 42.5 0.1 1.6e-10 41.3 0.1 1.5 1 1 0 1 1 1 1 Flavin reductase like domain Kelch_1 PF01344.25 OQS06535.1 - 0.15 11.7 0.0 0.35 10.5 0.0 1.7 1 0 0 1 1 1 0 Kelch motif Myosin_head PF00063.21 OQS06538.1 - 7.8e-203 675.4 0.0 1.1e-202 675.0 0.0 1.2 1 0 0 1 1 1 1 Myosin head (motor domain) PX PF00787.24 OQS06538.1 - 1.1e-12 47.9 0.0 8.6e-11 41.8 0.0 2.6 2 0 0 2 2 2 1 PX domain IQ PF00612.27 OQS06538.1 - 0.00024 20.6 0.4 0.00024 20.6 0.4 3.5 3 0 0 3 3 3 2 IQ calmodulin-binding motif SHOCT PF09851.9 OQS06538.1 - 0.00036 20.2 0.8 0.001 18.8 0.8 1.9 1 0 0 1 1 1 1 Short C-terminal domain DZR PF12773.7 OQS06538.1 - 0.011 15.8 1.0 0.027 14.5 1.0 1.6 1 0 0 1 1 1 0 Double zinc ribbon AAA_16 PF13191.6 OQS06538.1 - 0.091 13.1 0.0 0.091 13.1 0.0 3.4 3 1 0 3 3 3 0 AAA ATPase domain AAA_22 PF13401.6 OQS06538.1 - 0.093 13.0 0.0 0.5 10.6 0.0 2.3 2 0 0 2 2 2 0 AAA domain zf-ribbon_3 PF13248.6 OQS06538.1 - 0.14 11.6 3.0 0.33 10.4 3.0 1.6 1 0 0 1 1 1 0 zinc-ribbon domain TF_Zn_Ribbon PF08271.12 OQS06538.1 - 0.18 11.4 2.5 0.42 10.2 2.5 1.6 1 0 0 1 1 1 0 TFIIB zinc-binding ERM PF00769.19 OQS06538.1 - 2.3 8.0 40.6 4.9 6.9 40.6 1.6 1 0 0 1 1 1 0 Ezrin/radixin/moesin family HECT PF00632.25 OQS06539.1 - 7e-46 157.1 0.0 1.9e-45 155.7 0.0 1.7 2 0 0 2 2 2 1 HECT-domain (ubiquitin-transferase) SPRY PF00622.28 OQS06539.1 - 9.2e-46 154.9 4.9 3.4e-15 56.2 0.1 5.5 5 0 0 5 5 5 4 SPRY domain Laminin_G_3 PF13385.6 OQS06539.1 - 2.7e-30 105.5 0.0 9.2e-15 55.1 0.0 4.5 4 0 0 4 4 4 3 Concanavalin A-like lectin/glucanases superfamily Methyltransf_FA PF12248.8 OQS06539.1 - 1.5e-07 31.6 0.0 4.5e-07 30.1 0.0 1.8 1 0 0 1 1 1 1 Farnesoic acid 0-methyl transferase Laminin_G_2 PF02210.24 OQS06539.1 - 1.7e-07 31.9 0.0 0.0013 19.3 0.0 2.8 2 0 0 2 2 2 2 Laminin G domain MORN PF02493.20 OQS06539.1 - 2.4e-06 27.1 9.3 0.00063 19.5 0.3 4.5 4 0 0 4 4 4 2 MORN repeat UBA PF00627.31 OQS06539.1 - 2.3e-05 24.2 0.1 7.1e-05 22.6 0.1 1.9 1 0 0 1 1 1 1 UBA/TS-N domain zf-RanBP PF00641.18 OQS06539.1 - 0.00023 20.4 2.6 0.00066 18.9 2.6 1.9 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others DUF1080 PF06439.11 OQS06539.1 - 0.037 14.1 0.0 16 5.5 0.0 3.6 3 0 0 3 3 3 0 Domain of Unknown Function (DUF1080) DUF792 PF05632.11 OQS06539.1 - 0.055 13.3 1.6 46 3.8 0.1 3.6 3 0 0 3 3 3 0 Borrelia burgdorferi protein of unknown function (DUF792) CBS PF00571.28 OQS06540.1 - 3e-27 94.8 9.6 9.3e-09 35.6 0.1 4.7 4 1 0 4 4 4 4 CBS domain DisA_N PF02457.16 OQS06540.1 - 0.1 12.2 0.2 1 8.9 0.0 2.5 2 1 1 3 3 3 0 DisA bacterial checkpoint controller nucleotide-binding Ribosomal_L13 PF00572.18 OQS06541.1 - 6.8e-06 26.3 0.1 1.5e-05 25.2 0.0 1.6 2 0 0 2 2 2 1 Ribosomal protein L13 Nebulin PF00880.18 OQS06541.1 - 0.54 10.2 3.4 0.96 9.4 3.4 1.4 1 0 0 1 1 1 0 Nebulin repeat Pkinase PF00069.25 OQS06542.1 - 2.3e-20 73.1 0.0 3.8e-20 72.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQS06542.1 - 1e-06 28.2 0.0 2.2e-06 27.1 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase DUF5364 PF17322.2 OQS06542.1 - 0.76 10.1 5.7 0.2 12.0 2.2 1.7 1 1 1 2 2 2 0 Family of unknown function (DUF5364) HEAT PF02985.22 OQS06542.1 - 2 8.9 3.5 21 5.7 0.0 3.4 3 0 0 3 3 3 0 HEAT repeat zf-C2HC_2 PF13913.6 OQS06543.1 - 2.6e-12 46.3 16.9 1e-08 34.8 3.1 3.1 4 0 0 4 4 4 2 zinc-finger of a C2HC-type WW PF00397.26 OQS06543.1 - 1.3e-09 37.9 3.8 2.6e-09 37.0 3.8 1.5 1 0 0 1 1 1 1 WW domain DUF2318 PF10080.9 OQS06543.1 - 0.015 15.4 3.4 2.1 8.5 0.1 3.3 3 0 0 3 3 3 0 Predicted membrane protein (DUF2318) Vps39_2 PF10367.9 OQS06543.1 - 0.11 13.0 2.2 0.72 10.3 0.7 2.8 2 0 0 2 2 2 0 Vacuolar sorting protein 39 domain 2 zf-H2C2_2 PF13465.6 OQS06543.1 - 0.23 12.0 3.9 58 4.4 0.1 4.2 4 0 0 4 4 4 0 Zinc-finger double domain FYVE PF01363.21 OQS06543.1 - 0.24 11.6 8.0 10 6.3 1.5 3.4 3 0 0 3 3 3 0 FYVE zinc finger TRAF6_Z2 PF18048.1 OQS06543.1 - 0.44 10.7 0.1 0.44 10.7 0.1 2.7 4 0 0 4 4 4 0 TNF receptor-associated factor 6 zinc finger 2 TPR_1 PF00515.28 OQS06544.1 - 5.4e-45 149.5 37.5 1.5e-07 31.0 0.2 10.0 9 1 0 9 9 9 8 Tetratricopeptide repeat STI1 PF17830.1 OQS06544.1 - 9.4e-40 134.3 10.0 1.3e-23 82.7 1.4 2.9 3 0 0 3 3 2 2 STI1 domain TPR_2 PF07719.17 OQS06544.1 - 1.6e-33 112.1 33.6 4.5e-07 29.5 0.2 9.8 9 1 0 9 9 9 7 Tetratricopeptide repeat TPR_11 PF13414.6 OQS06544.1 - 1.7e-31 107.6 25.0 7.1e-09 35.2 0.0 7.0 6 1 1 7 7 7 6 TPR repeat TRP PF06011.12 OQS06544.1 - 3.2e-27 95.3 34.7 1.3e-25 90.0 34.7 2.1 1 1 0 1 1 1 1 Transient receptor potential (TRP) ion channel TPR_14 PF13428.6 OQS06544.1 - 1.5e-18 65.8 6.5 0.0072 17.1 0.0 7.9 4 2 4 8 8 8 3 Tetratricopeptide repeat TPR_8 PF13181.6 OQS06544.1 - 2e-17 61.9 34.1 0.00037 20.5 0.1 10.1 10 1 0 10 10 9 6 Tetratricopeptide repeat TPR_16 PF13432.6 OQS06544.1 - 2.3e-15 56.9 10.0 0.0003 21.4 0.0 5.3 3 2 2 5 5 5 3 Tetratricopeptide repeat TPR_12 PF13424.6 OQS06544.1 - 5.2e-14 52.3 15.4 8.4e-05 22.8 1.0 6.4 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_7 PF13176.6 OQS06544.1 - 6.2e-12 44.7 2.2 0.22 11.6 0.0 7.1 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_17 PF13431.6 OQS06544.1 - 7e-11 41.7 25.3 0.062 13.7 0.1 8.3 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_19 PF14559.6 OQS06544.1 - 2.3e-10 40.8 15.3 0.00099 19.6 0.3 5.9 4 2 3 7 7 7 4 Tetratricopeptide repeat TPR_9 PF13371.6 OQS06544.1 - 3.8e-06 27.0 0.0 0.64 10.2 0.1 4.0 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.6 OQS06544.1 - 1.9e-05 25.0 10.8 0.64 10.8 0.1 6.5 6 0 0 6 6 6 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 OQS06544.1 - 0.00019 21.4 5.7 1.5 8.9 0.0 5.1 4 1 1 5 5 5 1 Fis1 C-terminal tetratricopeptide repeat DUF3856 PF12968.7 OQS06544.1 - 0.16 12.0 3.4 0.48 10.5 0.3 3.1 3 0 0 3 3 3 0 Domain of Unknown Function (DUF3856) Hep_core_N PF08290.11 OQS06544.1 - 0.27 11.2 1.8 0.94 9.5 1.8 1.9 1 0 0 1 1 1 0 Hepatitis core protein, putative zinc finger ECM11 PF15463.6 OQS06544.1 - 0.36 11.4 1.7 3 8.4 0.6 2.5 2 0 0 2 2 2 0 Extracellular mutant protein 11 TPR_20 PF14561.6 OQS06544.1 - 0.56 10.6 6.4 17 5.8 0.1 4.2 3 1 1 4 4 4 0 Tetratricopeptide repeat TOM20_plant PF06552.12 OQS06544.1 - 0.63 9.8 6.6 3.5 7.3 2.4 3.7 1 1 2 3 3 3 0 Plant specific mitochondrial import receptor subunit TOM20 TPR_10 PF13374.6 OQS06544.1 - 0.77 9.7 22.1 4 7.4 0.0 7.4 8 0 0 8 8 8 0 Tetratricopeptide repeat Claudin_3 PF06653.11 OQS06544.1 - 2 8.4 12.5 1.1 9.2 3.2 2.7 2 0 0 2 2 2 0 Tight junction protein, Claudin-like TPR_19 PF14559.6 OQS06545.1 - 1.8e-41 140.5 50.8 5.3e-06 26.9 0.5 15.8 12 3 5 17 17 17 12 Tetratricopeptide repeat TPR_14 PF13428.6 OQS06545.1 - 6.3e-36 120.0 27.5 0.0019 18.8 0.1 19.1 12 5 9 21 21 19 7 Tetratricopeptide repeat TPR_2 PF07719.17 OQS06545.1 - 1.5e-35 118.4 50.9 0.00037 20.4 0.0 21.1 23 0 0 23 23 23 8 Tetratricopeptide repeat TPR_1 PF00515.28 OQS06545.1 - 1e-29 101.1 48.6 0.0012 18.6 0.0 17.6 20 0 0 20 20 19 7 Tetratricopeptide repeat TPR_16 PF13432.6 OQS06545.1 - 2.9e-29 101.4 10.1 0.0047 17.6 0.0 12.0 12 1 0 12 12 11 5 Tetratricopeptide repeat ANAPC3 PF12895.7 OQS06545.1 - 1.5e-20 73.2 45.3 0.0029 17.8 3.0 12.1 8 4 6 14 14 14 7 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.6 OQS06545.1 - 1.9e-19 69.7 41.4 0.034 14.4 0.4 14.5 12 3 2 14 14 14 5 Tetratricopeptide repeat TPR_8 PF13181.6 OQS06545.1 - 4.2e-15 54.6 52.6 0.077 13.2 0.6 17.5 20 0 0 20 20 17 5 Tetratricopeptide repeat TPR_17 PF13431.6 OQS06545.1 - 4.9e-15 54.8 26.9 0.68 10.4 0.2 15.0 16 1 0 16 16 15 3 Tetratricopeptide repeat TPR_11 PF13414.6 OQS06545.1 - 6.3e-15 54.6 24.5 3.9e-05 23.2 0.0 11.6 9 2 3 12 12 12 2 TPR repeat TPR_9 PF13371.6 OQS06545.1 - 7.8e-15 54.8 16.1 0.0034 17.5 0.1 7.8 6 1 0 7 7 6 3 Tetratricopeptide repeat TPR_7 PF13176.6 OQS06545.1 - 1.7e-13 49.5 33.9 0.057 13.5 0.1 13.3 16 1 1 17 17 12 4 Tetratricopeptide repeat TPR_15 PF13429.6 OQS06545.1 - 1.1e-12 47.8 34.5 6.1e-05 22.4 1.2 8.9 6 5 2 8 8 8 6 Tetratricopeptide repeat TPR_6 PF13174.6 OQS06545.1 - 2.9e-07 30.7 39.8 0.037 14.7 0.2 15.3 18 0 0 18 18 14 2 Tetratricopeptide repeat ChAPs PF09295.10 OQS06545.1 - 9.8e-06 24.8 19.3 0.0027 16.8 2.0 5.7 4 1 1 5 5 5 3 ChAPs (Chs5p-Arf1p-binding proteins) TPR_10 PF13374.6 OQS06545.1 - 1.1e-05 25.1 12.9 0.68 9.9 0.0 8.7 9 0 0 9 9 9 1 Tetratricopeptide repeat TPR_20 PF14561.6 OQS06545.1 - 1.8e-05 25.0 23.2 0.26 11.6 0.9 9.3 8 2 1 10 10 8 2 Tetratricopeptide repeat Coatomer_E PF04733.14 OQS06545.1 - 0.00018 21.1 25.4 0.0015 18.0 0.1 7.7 8 3 1 9 9 9 2 Coatomer epsilon subunit Fis1_TPR_C PF14853.6 OQS06545.1 - 0.00018 21.5 15.7 5.6 7.1 0.0 9.7 11 0 0 11 11 11 1 Fis1 C-terminal tetratricopeptide repeat BTAD PF03704.17 OQS06545.1 - 0.0012 19.3 13.0 1 9.8 0.1 6.0 6 0 0 6 6 6 1 Bacterial transcriptional activator domain TPR_21 PF09976.9 OQS06545.1 - 0.0018 18.0 33.0 0.14 11.9 4.5 7.3 5 2 2 7 7 7 1 Tetratricopeptide repeat-like domain HrpB1_HrpK PF09613.10 OQS06545.1 - 0.0083 15.8 13.4 0.14 11.8 0.1 6.8 6 2 3 9 9 9 1 Bacterial type III secretion protein (HrpB1_HrpK) TPR_4 PF07721.14 OQS06545.1 - 0.012 16.2 6.3 52 4.9 0.3 6.7 8 0 0 8 8 4 0 Tetratricopeptide repeat PknG_TPR PF16918.5 OQS06545.1 - 0.024 13.4 7.6 0.22 10.2 0.0 4.5 4 1 1 5 5 5 0 Protein kinase G tetratricopeptide repeat MIT PF04212.18 OQS06545.1 - 0.033 14.3 23.6 40 4.4 0.0 9.8 10 0 0 10 10 9 0 MIT (microtubule interacting and transport) domain DUF4919 PF16266.5 OQS06545.1 - 0.075 13.0 0.0 0.075 13.0 0.0 5.6 6 1 1 7 7 7 0 Domain of unknown function (DUF4919) SHNi-TPR PF10516.9 OQS06545.1 - 0.087 12.3 5.4 7.2 6.2 0.1 4.6 4 0 0 4 4 4 0 SHNi-TPR YfiO PF13525.6 OQS06545.1 - 0.16 11.6 0.1 0.16 11.6 0.1 5.2 6 0 0 6 6 6 0 Outer membrane lipoprotein RPN7 PF10602.9 OQS06545.1 - 0.56 9.9 16.8 9.4 5.9 0.8 6.9 8 0 0 8 8 7 0 26S proteasome subunit RPN7 Peptidase_M3 PF01432.20 OQS06546.1 - 2.9e-65 221.3 0.0 5.1e-64 217.2 0.0 1.9 1 1 0 1 1 1 1 Peptidase family M3 Peptidase_M50B PF13398.6 OQS06546.1 - 0.022 14.4 0.0 0.034 13.8 0.0 1.3 1 0 0 1 1 1 0 Peptidase M50B-like Tenui_PVC2 PF06656.11 OQS06546.1 - 0.16 9.8 0.0 0.21 9.4 0.0 1.1 1 0 0 1 1 1 0 Tenuivirus PVC2 protein Ank_2 PF12796.7 OQS06547.1 - 6.6e-05 23.4 0.2 8.8e-05 23.0 0.2 1.3 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQS06547.1 - 9.5e-05 22.9 0.6 0.0029 18.1 0.6 2.1 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 OQS06547.1 - 0.033 14.5 0.3 6.1 7.3 0.0 2.3 1 1 1 2 2 2 0 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQS06547.1 - 0.087 13.4 0.1 20 6.1 0.0 2.4 1 1 1 2 2 2 0 Ankyrin repeat Peptidase_M3 PF01432.20 OQS06549.1 - 3.6e-20 72.7 1.0 5.1e-20 72.2 1.0 1.2 1 0 0 1 1 1 1 Peptidase family M3 Glyco_hydro_53 PF07745.13 OQS06549.1 - 0.042 12.8 0.7 0.38 9.7 0.3 2.0 1 1 1 2 2 2 0 Glycosyl hydrolase family 53 Nterm_IS4 PF13006.7 OQS06549.1 - 0.12 12.6 0.2 2.1 8.6 0.0 2.5 3 0 0 3 3 3 0 Insertion element 4 transposase N-terminal TPR_2 PF07719.17 OQS06550.1 - 3.3e-15 54.9 10.8 1.3e-05 25.0 0.7 5.3 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_1 PF00515.28 OQS06550.1 - 7.1e-14 50.9 8.9 0.00036 20.2 0.4 4.5 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_11 PF13414.6 OQS06550.1 - 9.5e-13 47.6 3.9 0.0015 18.2 0.0 3.4 2 1 1 3 3 3 3 TPR repeat TPR_8 PF13181.6 OQS06550.1 - 2.3e-12 46.1 3.5 0.0042 17.2 0.0 3.8 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.6 OQS06550.1 - 3.3e-10 40.1 14.7 0.0035 17.6 3.5 5.4 1 1 4 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.6 OQS06550.1 - 4.5e-09 36.8 2.0 4.6e-05 24.0 0.0 3.5 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 OQS06550.1 - 7.7e-09 35.9 4.3 0.00079 19.9 0.4 3.4 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 OQS06550.1 - 1.5e-08 34.8 5.7 0.0063 17.2 0.5 4.8 3 1 2 5 5 5 2 Tetratricopeptide repeat TPR_10 PF13374.6 OQS06550.1 - 4.1e-07 29.7 4.6 0.18 11.7 0.0 4.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.6 OQS06550.1 - 1e-06 28.3 5.1 0.16 12.1 0.0 4.0 4 0 0 4 4 4 2 Tetratricopeptide repeat ANAPC3 PF12895.7 OQS06550.1 - 2.3e-06 27.7 7.2 9.6e-06 25.7 3.1 2.8 1 1 1 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.6 OQS06550.1 - 6.3e-05 22.3 10.3 0.013 14.7 5.2 2.2 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.6 OQS06550.1 - 9.8e-05 22.5 6.8 0.13 12.7 0.0 4.4 5 0 0 5 5 5 2 Tetratricopeptide repeat Sel1 PF08238.12 OQS06550.1 - 0.00013 22.5 5.1 0.085 13.6 0.1 4.6 5 0 0 5 5 5 1 Sel1 repeat TPR_21 PF09976.9 OQS06550.1 - 0.00051 19.8 3.2 0.73 9.5 0.2 3.0 2 1 1 3 3 3 2 Tetratricopeptide repeat-like domain TPR_3 PF07720.12 OQS06550.1 - 0.019 15.0 3.1 14 5.8 0.7 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_9 PF13371.6 OQS06550.1 - 0.1 12.8 2.4 0.8 9.9 1.3 2.7 2 1 0 3 3 2 0 Tetratricopeptide repeat TPR_6 PF13174.6 OQS06550.1 - 0.48 11.2 8.6 65 4.5 0.1 4.7 4 0 0 4 4 4 0 Tetratricopeptide repeat BTB_2 PF02214.22 OQS06551.1 - 2e-09 37.7 0.0 3.2e-09 37.0 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain ADH_zinc_N PF00107.26 OQS06552.1 - 2.3e-14 53.5 0.1 4.2e-14 52.6 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 OQS06552.1 - 1.3e-07 31.5 0.0 1.9e-05 24.5 0.0 2.9 2 1 1 3 3 3 1 Alcohol dehydrogenase GroES-like domain Peripla_BP_4 PF13407.6 OQS06552.1 - 1.3e-05 24.9 0.7 3.4e-05 23.5 0.5 1.6 1 1 0 1 1 1 1 Periplasmic binding protein domain ADH_N_2 PF16884.5 OQS06552.1 - 0.005 16.7 0.0 0.0093 15.8 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase NAD_binding_10 PF13460.6 OQS06552.1 - 0.013 15.4 0.1 0.024 14.5 0.1 1.4 1 0 0 1 1 1 0 NAD(P)H-binding ADH_zinc_N_2 PF13602.6 OQS06552.1 - 0.015 16.3 0.1 0.14 13.2 0.0 2.2 1 1 1 2 2 2 0 Zinc-binding dehydrogenase CoA_binding_2 PF13380.6 OQS06552.1 - 0.022 15.2 0.2 0.071 13.6 0.2 1.9 1 1 0 1 1 1 0 CoA binding domain NmrA PF05368.13 OQS06552.1 - 0.026 14.1 0.2 0.045 13.3 0.2 1.4 1 0 0 1 1 1 0 NmrA-like family NAD_binding_2 PF03446.15 OQS06552.1 - 0.027 14.6 0.0 0.056 13.6 0.0 1.5 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase TrkA_N PF02254.18 OQS06552.1 - 0.076 13.3 0.3 0.15 12.3 0.3 1.4 1 0 0 1 1 1 0 TrkA-N domain DUF4215 PF13948.6 OQS06553.1 - 2.4e-05 24.7 4.2 2.4e-05 24.7 4.2 6.7 8 1 1 9 9 9 1 Domain of unknown function (DUF4215) Ricin_B_lectin PF00652.22 OQS06554.1 - 4.5e-23 81.9 8.0 2.3e-16 60.2 1.1 2.4 2 0 0 2 2 2 2 Ricin-type beta-trefoil lectin domain CDtoxinA PF03498.14 OQS06554.1 - 4.5e-05 23.1 5.9 0.096 12.3 0.4 3.3 2 1 1 3 3 3 3 Cytolethal distending toxin A/C domain RicinB_lectin_2 PF14200.6 OQS06554.1 - 0.00029 21.5 8.9 0.073 13.8 1.8 3.6 1 1 2 3 3 3 3 Ricin-type beta-trefoil lectin domain-like Ubiquitin_2 PF14560.6 OQS06554.1 - 0.075 13.5 0.1 2 9.0 0.0 3.0 3 0 0 3 3 3 0 Ubiquitin-like domain DUF1322 PF07032.11 OQS06554.1 - 0.4 11.2 0.1 0.4 11.2 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1322) AltA1 PF16541.5 OQS06554.1 - 0.59 11.0 3.4 0.33 11.8 1.1 1.7 2 0 0 2 2 2 0 Alternaria alternata allergen 1 BT1 PF03092.16 OQS06556.1 - 2.2e-52 178.0 72.2 1.1e-15 56.9 3.9 11.2 10 1 1 11 11 11 8 BT1 family ATP_bind_3 PF01171.20 OQS06556.1 - 5.6e-37 127.3 0.0 1e-36 126.4 0.0 1.5 1 0 0 1 1 1 1 PP-loop family DUF924 PF06041.11 OQS06556.1 - 2.7e-23 83.0 2.0 4.8e-23 82.2 2.0 1.4 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF924) MFS_1 PF07690.16 OQS06556.1 - 3.3e-18 65.8 119.3 9.9e-06 24.7 19.7 9.1 3 3 5 8 8 8 7 Major Facilitator Superfamily PUCC PF03209.15 OQS06556.1 - 3.2e-10 39.6 21.1 0.00011 21.4 2.3 5.9 5 1 0 5 5 5 4 PUCC protein QueC PF06508.13 OQS06556.1 - 3.5e-05 23.4 0.0 0.011 15.3 0.0 2.4 2 0 0 2 2 2 2 Queuosine biosynthesis protein QueC Asn_synthase PF00733.21 OQS06556.1 - 0.00025 20.8 0.0 0.00044 20.0 0.0 1.3 1 0 0 1 1 1 1 Asparagine synthase NAD_synthase PF02540.17 OQS06556.1 - 0.0023 17.1 0.0 0.005 16.0 0.0 1.5 1 0 0 1 1 1 1 NAD synthase tRNA_Me_trans PF03054.16 OQS06556.1 - 0.005 15.7 0.0 0.0082 15.0 0.0 1.2 1 0 0 1 1 1 1 tRNA methyl transferase DUF2964 PF11177.8 OQS06556.1 - 0.028 14.6 5.4 48 4.2 0.1 5.1 4 0 0 4 4 4 0 Protein of unknown function (DUF2964) YCII PF03795.14 OQS06556.1 - 0.035 14.5 0.3 1.1e+02 3.3 0.0 4.2 5 0 0 5 5 3 0 YCII-related domain ThiI PF02568.14 OQS06556.1 - 0.058 13.0 0.0 1.4 8.5 0.0 2.9 1 1 0 1 1 1 0 Thiamine biosynthesis protein (ThiI) PAPS_reduct PF01507.19 OQS06556.1 - 0.075 13.1 0.0 0.18 11.8 0.0 1.7 1 0 0 1 1 1 0 Phosphoadenosine phosphosulfate reductase family TM_helix PF05552.12 OQS06556.1 - 0.096 12.7 19.2 2.7 8.0 0.5 5.1 4 0 0 4 4 4 0 Conserved TM helix DUF1375 PF07119.12 OQS06556.1 - 0.79 10.2 14.5 5.6 7.4 0.2 6.1 7 0 0 7 7 7 0 Protein of unknown function (DUF1375) CPSase_L_D2 PF02786.17 OQS06557.1 - 2.8e-79 265.5 0.1 4.5e-79 264.8 0.1 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 OQS06557.1 - 1.6e-43 147.8 1.6 3.4e-43 146.7 0.1 2.1 2 0 0 2 2 2 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 OQS06557.1 - 2e-35 121.1 0.0 6.7e-35 119.5 0.0 2.0 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.22 OQS06557.1 - 7.5e-16 57.7 3.4 2.1e-15 56.3 3.4 1.8 1 0 0 1 1 1 1 Biotin-requiring enzyme PCC_BT PF18140.1 OQS06557.1 - 6.3e-11 42.7 0.0 1.9e-10 41.2 0.0 1.8 2 0 0 2 2 1 1 Propionyl-coenzyme A carboxylase BT domain ATP-grasp PF02222.22 OQS06557.1 - 4.3e-09 36.2 0.1 1e-08 35.0 0.1 1.6 1 0 0 1 1 1 1 ATP-grasp domain Dala_Dala_lig_C PF07478.13 OQS06557.1 - 1.6e-08 34.4 0.1 5.3e-08 32.6 0.1 1.9 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus Biotin_lipoyl_2 PF13533.6 OQS06557.1 - 0.0038 17.0 0.8 0.0085 15.9 0.8 1.6 1 0 0 1 1 1 1 Biotin-lipoyl like ATP-grasp_5 PF13549.6 OQS06557.1 - 0.0067 15.9 0.0 0.026 14.0 0.0 2.0 2 0 0 2 2 2 1 ATP-grasp domain ATPgrasp_ST PF14397.6 OQS06557.1 - 0.0094 15.2 0.0 0.028 13.7 0.0 1.7 2 0 0 2 2 2 1 Sugar-transfer associated ATP-grasp ATP-grasp_3 PF02655.14 OQS06557.1 - 0.011 15.8 0.4 0.023 14.7 0.0 1.8 2 0 0 2 2 2 0 ATP-grasp domain RnfC_N PF13375.6 OQS06557.1 - 0.018 15.0 0.4 0.043 13.8 0.4 1.6 1 0 0 1 1 1 0 RnfC Barrel sandwich hybrid domain BT1 PF03092.16 OQS06558.1 - 7.6e-13 47.5 1.8 4.6e-11 41.6 0.8 3.6 4 0 0 4 4 4 3 BT1 family DUF1375 PF07119.12 OQS06558.1 - 0.51 10.8 4.4 19 5.8 0.1 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1375) Asp PF00026.23 OQS06559.1 - 2.9e-60 204.3 0.0 4.3e-60 203.8 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 OQS06559.1 - 1.2e-12 48.5 0.4 1e-05 25.8 0.1 2.5 1 1 1 2 2 2 2 Xylanase inhibitor N-terminal TAXi_C PF14541.6 OQS06559.1 - 2.7e-05 24.0 0.0 5.7e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.6 OQS06559.1 - 0.011 16.4 0.1 0.089 13.4 0.0 2.5 2 1 0 2 2 2 0 Aspartyl protease Dicty_CAR PF05462.11 OQS06559.1 - 3.2 6.8 16.3 5.1 6.1 15.7 1.5 1 1 0 1 1 1 0 Slime mold cyclic AMP receptor Cupin_8 PF13621.6 OQS06560.1 - 3.7e-44 151.3 0.0 5e-44 150.9 0.0 1.2 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.12 OQS06560.1 - 5.6e-12 45.7 0.1 1.4e-11 44.5 0.1 1.8 1 1 0 1 1 1 1 Cupin superfamily protein TPR_19 PF14559.6 OQS06560.1 - 0.021 15.3 0.1 0.048 14.2 0.1 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat JmjC PF02373.22 OQS06560.1 - 0.03 14.7 0.0 0.063 13.7 0.0 1.7 1 1 0 1 1 1 0 JmjC domain, hydroxylase Cupin_1 PF00190.22 OQS06560.1 - 0.16 11.6 0.0 0.31 10.6 0.0 1.5 1 1 0 1 1 1 0 Cupin LBR_tudor PF09465.10 OQS06562.1 - 7.2e-20 70.5 7.2 0.0014 18.4 0.0 6.5 6 0 0 6 6 6 4 Lamin-B receptor of TUDOR domain Agenet PF05641.12 OQS06562.1 - 2.2e-18 66.4 12.9 0.0025 18.3 0.1 7.0 6 0 0 6 6 6 4 Agenet domain EF-hand_7 PF13499.6 OQS06562.1 - 6.7e-18 64.9 0.7 7.2e-09 36.0 0.1 4.0 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_1 PF00036.32 OQS06562.1 - 1.1e-15 55.9 1.1 2e-05 23.8 0.1 4.4 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.6 OQS06562.1 - 8.9e-12 43.9 4.9 0.00023 20.8 0.2 5.2 4 0 0 4 4 4 3 EF-hand domain EF-hand_5 PF13202.6 OQS06562.1 - 3.2e-11 42.2 3.8 0.00033 20.0 0.1 4.0 3 0 0 3 3 3 2 EF hand DUF4537 PF15057.6 OQS06562.1 - 7.1e-11 42.2 3.2 0.0019 18.2 0.2 4.3 4 1 0 4 4 4 3 Domain of unknown function (DUF4537) SAM_1 PF00536.30 OQS06562.1 - 7.5e-10 39.1 0.1 2.1e-09 37.7 0.1 1.8 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) TUDOR_5 PF18359.1 OQS06562.1 - 2.6e-09 36.6 14.8 0.0093 15.6 0.3 5.5 5 0 0 5 5 5 4 Histone methyltransferase Tudor domain 1 SAM_2 PF07647.17 OQS06562.1 - 1e-08 35.1 0.1 2.8e-08 33.7 0.1 1.8 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) EF-hand_8 PF13833.6 OQS06562.1 - 2.2e-08 33.8 0.1 0.00029 20.6 0.0 2.8 2 0 0 2 2 2 2 EF-hand domain pair DUF1325 PF07039.11 OQS06562.1 - 3e-08 33.8 1.5 0.31 11.1 0.0 5.8 1 1 5 6 6 6 2 SGF29 tudor-like domain TUDOR PF00567.24 OQS06562.1 - 1.4e-05 25.1 1.7 0.53 10.3 0.0 4.4 3 1 1 4 4 4 1 Tudor domain dCMP_cyt_deam_1 PF00383.23 OQS06562.1 - 7.2e-05 22.6 0.0 0.00015 21.6 0.0 1.5 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region 53-BP1_Tudor PF09038.10 OQS06562.1 - 0.0017 18.3 7.9 1.6 8.7 0.2 4.5 4 1 0 4 4 4 2 Tumour suppressor p53-binding protein-1 Tudor LPD30 PF18850.1 OQS06562.1 - 0.004 16.9 0.0 86 2.9 0.0 5.5 5 1 0 5 5 5 0 Large polyvalent protein associated domain 30 Tudor_FRX1 PF18336.1 OQS06562.1 - 0.013 15.4 0.9 1.4 8.9 0.0 3.5 4 0 0 4 4 3 0 Fragile X mental retardation Tudor domain EF-hand_4 PF12763.7 OQS06562.1 - 0.039 13.9 0.6 2.1 8.4 0.0 2.7 2 0 0 2 2 2 0 Cytoskeletal-regulatory complex EF hand eIF-1a PF01176.19 OQS06562.1 - 0.046 13.5 0.6 19 5.1 0.0 4.7 6 0 0 6 6 6 0 Translation initiation factor 1A / IF-1 SH3_15 PF18346.1 OQS06562.1 - 0.12 12.7 8.0 35 4.8 0.6 5.9 5 1 0 5 5 5 0 Mind bomb SH3 repeat domain SPARC_Ca_bdg PF10591.9 OQS06562.1 - 0.53 10.6 5.0 4 7.8 0.0 3.3 3 0 0 3 3 2 0 Secreted protein acidic and rich in cysteine Ca binding region LOH1CR12 PF10158.9 OQS06563.1 - 0.18 11.8 6.9 5.1 7.1 0.6 2.7 2 0 0 2 2 2 0 Tumour suppressor protein RNA_pol_Rpb5_C PF01191.19 OQS06564.1 - 8.9e-33 112.0 0.4 2.1e-32 110.8 0.4 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb5, C-terminal domain RNA_pol_Rpb5_N PF03871.14 OQS06564.1 - 1.5e-29 102.4 0.0 2.4e-29 101.7 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb5, N-terminal domain Mrr_cat PF04471.12 OQS06564.1 - 0.0052 16.8 0.0 0.022 14.7 0.0 2.1 2 1 0 2 2 2 1 Restriction endonuclease BamHI PF02923.15 OQS06564.1 - 0.045 13.5 0.0 0.075 12.8 0.0 1.4 1 0 0 1 1 1 0 Restriction endonuclease BamHI Angiomotin_C PF12240.8 OQS06566.1 - 0.074 12.6 3.5 0.12 11.9 3.5 1.3 1 0 0 1 1 1 0 Angiomotin C terminal Rhabdo_M1 PF03342.13 OQS06566.1 - 0.1 12.0 0.4 0.22 10.8 0.2 1.6 1 1 1 2 2 2 0 Rhabdovirus M1 matrix protein (M1 polymerase-associated protein) TSC22 PF01166.18 OQS06566.1 - 0.7 10.2 4.6 2.9 8.3 1.0 2.3 2 0 0 2 2 2 0 TSC-22/dip/bun family LtrA PF06772.11 OQS06567.1 - 3.6e-30 105.4 26.9 5e-30 104.9 26.9 1.1 1 0 0 1 1 1 1 Bacterial low temperature requirement A protein (LtrA) FadA PF09403.10 OQS06567.1 - 9.7 6.7 16.4 6.4 7.3 2.2 2.8 2 1 0 2 2 2 0 Adhesion protein FadA TTL PF03133.15 OQS06568.1 - 2.7e-83 279.5 0.0 4.5e-83 278.8 0.0 1.3 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 OQS06568.1 - 1.3e-05 24.6 0.0 0.00098 18.4 0.0 2.4 2 0 0 2 2 2 2 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 OQS06568.1 - 0.00037 19.8 0.0 0.24 10.6 0.0 2.2 2 0 0 2 2 2 2 Sugar-transfer associated ATP-grasp DUF1418 PF07214.12 OQS06569.1 - 5.7 6.9 9.9 0.57 10.1 0.7 3.1 3 1 0 3 3 3 0 Protein of unknown function (DUF1418) MARVEL PF01284.23 OQS06569.1 - 9 6.3 14.1 5 7.2 0.9 3.0 1 1 0 2 2 2 0 Membrane-associating domain LtrA PF06772.11 OQS06570.1 - 3.7e-22 79.0 18.8 4.1e-22 78.9 18.8 1.0 1 0 0 1 1 1 1 Bacterial low temperature requirement A protein (LtrA) Ion_trans_2 PF07885.16 OQS06570.1 - 0.028 14.4 2.9 0.028 14.4 2.9 3.0 3 1 0 3 3 3 0 Ion channel TPX2_importin PF12214.8 OQS06571.1 - 0.0051 17.0 1.5 0.0058 16.8 1.5 1.1 1 0 0 1 1 1 1 Cell cycle regulated microtubule associated protein MTES_1575 PF18741.1 OQS06571.1 - 0.029 14.5 0.8 0.043 14.0 0.2 1.6 1 1 1 2 2 2 0 REase_MTES_1575 Mus7 PF09462.10 OQS06571.1 - 0.047 12.6 0.2 0.057 12.3 0.2 1.0 1 0 0 1 1 1 0 Mus7/MMS22 family FYVE PF01363.21 OQS06573.1 - 5e-16 58.6 8.7 9e-16 57.8 8.7 1.4 1 0 0 1 1 1 1 FYVE zinc finger START PF01852.19 OQS06573.1 - 1.2e-05 24.8 0.1 2.8e-05 23.6 0.1 1.6 2 0 0 2 2 2 1 START domain FYVE_2 PF02318.16 OQS06573.1 - 0.0017 18.6 6.5 0.003 17.8 6.5 1.3 1 0 0 1 1 1 1 FYVE-type zinc finger zf-Sec23_Sec24 PF04810.15 OQS06573.1 - 0.51 10.4 8.4 3.5 7.8 4.2 2.6 2 0 0 2 2 2 0 Sec23/Sec24 zinc finger zf-C2HC5 PF06221.13 OQS06573.1 - 0.53 10.3 10.1 1.6 8.8 10.1 1.8 1 1 0 1 1 1 0 Putative zinc finger motif, C2HC5-type C1_1 PF00130.22 OQS06573.1 - 6.5 6.7 11.4 1.6 8.7 8.2 1.7 1 1 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) DLL_N PF12413.8 OQS06573.1 - 6.8 8.0 16.8 1.1 10.6 4.5 2.8 2 0 0 2 2 2 0 Homeobox protein distal-less-like N terminal Syndecan PF01034.20 OQS06574.1 - 0.0015 18.4 0.2 0.0027 17.6 0.2 1.3 1 0 0 1 1 1 1 Syndecan domain DUF1043 PF06295.12 OQS06574.1 - 0.19 11.7 0.0 0.3 11.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) MFS_1 PF07690.16 OQS06575.1 - 3.6e-29 101.8 136.4 4.2e-14 52.2 14.1 8.6 3 3 6 9 9 9 8 Major Facilitator Superfamily Sugar_tr PF00083.24 OQS06575.1 - 5.4e-06 25.5 3.7 5.4e-06 25.5 3.7 5.7 6 0 0 6 6 6 3 Sugar (and other) transporter ANAPC4 PF12896.7 OQS06576.1 - 0.073 12.6 0.1 0.11 12.0 0.1 1.3 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 4 CENP-F_leu_zip PF10473.9 OQS06577.1 - 0.00042 20.4 6.9 0.00042 20.4 6.9 3.0 1 1 1 2 2 2 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Aminotran_4 PF01063.19 OQS06577.1 - 0.075 12.9 0.9 0.15 11.9 0.9 1.5 1 0 0 1 1 1 0 Amino-transferase class IV CENP-H PF05837.12 OQS06577.1 - 0.32 11.4 24.1 0.24 11.8 2.1 3.0 2 1 0 2 2 2 0 Centromere protein H (CENP-H) Fungal_TACC PF12709.7 OQS06577.1 - 0.43 11.1 14.4 0.2 12.1 1.9 3.5 3 0 0 3 3 3 0 Fungal Transforming acidic coiled-coil (TACC) proteins Cep57_CLD_2 PF14197.6 OQS06577.1 - 0.9 9.7 27.7 0.12 12.4 5.1 4.5 2 1 1 3 3 3 0 Centrosome localisation domain of PPC89 DUF745 PF05335.13 OQS06577.1 - 2.2 7.9 29.9 0.99 9.1 14.7 2.4 1 1 0 2 2 2 0 Protein of unknown function (DUF745) DUF948 PF06103.11 OQS06577.1 - 2.9 8.2 4.7 0.83 10.0 0.4 2.3 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) DHR10 PF18595.1 OQS06577.1 - 6 6.9 29.8 0.21 11.7 14.2 3.6 1 1 2 3 3 3 0 Designed helical repeat protein 10 domain LPP PF04728.13 OQS06577.1 - 9.9 6.6 11.9 12 6.3 2.9 3.6 3 1 1 4 4 4 0 Lipoprotein leucine-zipper DAGAT PF03982.13 OQS06578.1 - 8.8e-33 113.5 0.5 1.1e-32 113.1 0.5 1.2 1 0 0 1 1 1 1 Diacylglycerol acyltransferase Glyco_transf_17 PF04724.13 OQS06578.1 - 0.01 14.9 0.2 0.016 14.3 0.2 1.2 1 0 0 1 1 1 0 Glycosyltransferase family 17 NUC194 PF08163.12 OQS06580.1 - 1.7e-33 116.1 6.7 1e-23 84.0 1.9 2.6 1 1 1 2 2 2 2 NUC194 domain HEAT PF02985.22 OQS06580.1 - 5.3e-05 23.1 2.9 24 5.6 0.1 6.0 5 0 0 5 5 5 1 HEAT repeat TAF6_C PF07571.13 OQS06580.1 - 0.002 18.4 1.5 2.6 8.4 0.1 4.8 4 1 0 4 4 4 2 TAF6 C-terminal HEAT repeat domain HEAT_2 PF13646.6 OQS06580.1 - 0.011 16.1 5.5 22 5.5 0.0 5.1 3 1 3 6 6 6 0 HEAT repeats zf-RING_2 PF13639.6 OQS06581.1 - 1.5e-46 156.5 60.2 6.3e-13 48.8 7.7 6.7 5 1 0 5 5 5 5 Ring finger domain zf-rbx1 PF12678.7 OQS06581.1 - 1e-35 121.8 54.4 9e-10 38.7 6.7 5.7 4 1 0 4 4 4 4 RING-H2 zinc finger domain PX PF00787.24 OQS06581.1 - 2.4e-34 117.7 5.6 1e-09 38.3 0.1 4.6 4 0 0 4 4 4 4 PX domain zf-RING_11 PF17123.5 OQS06581.1 - 1.9e-28 97.9 43.7 2.2e-08 33.7 3.9 7.0 6 0 0 6 6 6 5 RING-like zinc finger zf-C3HC4_2 PF13923.6 OQS06581.1 - 1.3e-27 95.3 60.1 6.3e-08 32.3 11.0 6.6 6 0 0 6 6 6 4 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 OQS06581.1 - 2.9e-24 84.6 56.3 3.4e-07 30.0 10.7 5.7 4 1 0 4 4 4 4 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OQS06581.1 - 2.1e-22 78.8 41.2 1.6e-06 28.0 2.7 5.3 4 1 0 4 4 4 4 RING-type zinc-finger zf-ANAPC11 PF12861.7 OQS06581.1 - 4.6e-21 74.7 34.5 4.6e-06 26.6 2.4 5.4 4 2 0 4 4 4 4 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.6 OQS06581.1 - 1.1e-16 60.5 52.8 1.8e-05 24.6 5.8 5.6 4 2 0 4 4 4 4 zinc-RING finger domain zf-C3HC4_3 PF13920.6 OQS06581.1 - 2.3e-15 56.2 48.7 0.00012 21.8 3.5 6.1 6 0 0 6 6 6 4 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 OQS06581.1 - 2.1e-08 33.7 40.4 0.0089 15.6 6.2 5.1 4 0 0 4 4 4 4 Zinc-ribbon, C4HC2 type Prok-RING_4 PF14447.6 OQS06581.1 - 1.6e-07 31.1 63.0 0.00046 20.0 0.8 6.6 7 1 1 8 8 8 4 Prokaryotic RING finger family 4 zf-C3H2C3 PF17122.5 OQS06581.1 - 0.00041 20.3 37.9 0.029 14.4 2.7 5.1 4 0 0 4 4 4 3 Zinc-finger zinc_ribbon_16 PF17034.5 OQS06581.1 - 0.0091 16.2 37.4 0.45 10.7 5.9 5.0 4 0 0 4 4 4 3 Zinc-ribbon like family RINGv PF12906.7 OQS06581.1 - 0.077 13.1 58.7 0.099 12.8 7.8 5.5 6 0 0 6 6 5 0 RING-variant domain zf-Nse PF11789.8 OQS06581.1 - 0.18 11.6 41.9 0.26 11.1 3.4 5.0 5 0 0 5 5 4 0 Zinc-finger of the MIZ type in Nse subunit FANCL_C PF11793.8 OQS06581.1 - 0.96 9.7 51.4 0.019 15.1 5.2 6.4 5 3 0 5 5 5 0 FANCL C-terminal domain Rad50_zn_hook PF04423.14 OQS06581.1 - 2.4 8.0 20.5 0.44 10.4 0.1 5.3 6 0 0 6 6 5 0 Rad50 zinc hook motif zf-RING_2 PF13639.6 OQS06583.1 - 1.1e-14 54.4 4.8 3.2e-14 53.0 4.8 1.8 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 OQS06583.1 - 2.2e-11 43.9 4.0 7.6e-11 42.1 4.0 2.0 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 OQS06583.1 - 8.8e-10 38.3 5.2 2.3e-09 36.9 5.2 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 OQS06583.1 - 1.7e-09 37.3 5.0 1.7e-09 37.3 5.0 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OQS06583.1 - 8.1e-09 35.4 1.7 1.7e-08 34.3 1.7 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_11 PF17123.5 OQS06583.1 - 3.9e-08 32.9 2.0 8.5e-08 31.8 2.0 1.6 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_5 PF14634.6 OQS06583.1 - 4.1e-08 33.0 3.5 9.7e-08 31.9 3.5 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 OQS06583.1 - 4.4e-08 33.1 2.3 1.6e-07 31.3 2.3 1.9 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.6 OQS06583.1 - 2.4e-07 30.5 2.2 5.8e-07 29.3 2.2 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) PX PF00787.24 OQS06583.1 - 1.5e-05 24.9 0.0 2.8e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 PX domain Prok-RING_4 PF14447.6 OQS06583.1 - 6.9e-05 22.6 3.1 0.00016 21.5 3.1 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 Zn_ribbon_17 PF17120.5 OQS06583.1 - 0.00023 20.7 2.8 0.00064 19.3 2.8 1.8 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type FANCL_C PF11793.8 OQS06583.1 - 0.00031 20.9 4.8 0.00031 20.9 4.8 2.6 2 1 0 2 2 2 1 FANCL C-terminal domain RINGv PF12906.7 OQS06583.1 - 0.00085 19.4 4.5 0.0031 17.6 4.5 2.0 1 0 0 1 1 1 1 RING-variant domain zf-RING_4 PF14570.6 OQS06583.1 - 0.0021 17.8 4.2 0.0056 16.4 4.2 1.7 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-Nse PF11789.8 OQS06583.1 - 0.016 15.0 1.5 0.064 13.1 1.5 2.1 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Prok-RING_1 PF14446.6 OQS06583.1 - 0.017 15.0 3.2 0.16 11.9 0.8 2.6 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 PHD PF00628.29 OQS06583.1 - 0.018 14.9 4.9 0.018 14.9 4.9 2.0 2 0 0 2 2 1 0 PHD-finger zf-C3HC4_4 PF15227.6 OQS06583.1 - 0.22 11.7 5.3 1 9.5 5.0 2.4 2 1 0 2 2 1 0 zinc finger of C3HC4-type, RING Endonuclease_7 PF02945.15 OQS06583.1 - 2.6 8.0 7.9 1.6 8.7 0.1 3.0 2 1 0 2 2 2 0 Recombination endonuclease VII GET2 PF08690.10 OQS06584.1 - 0.0013 18.5 4.6 0.003 17.3 4.6 1.5 1 1 0 1 1 1 1 GET complex subunit GET2 DUF4366 PF14283.6 OQS06584.1 - 0.0021 18.1 0.5 0.0021 18.1 0.5 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4366) RNase_J_C PF17770.1 OQS06584.1 - 0.0031 18.5 4.0 0.32 12.1 0.1 2.9 2 1 1 3 3 3 2 Ribonuclease J C-terminal domain PAP_PilO PF06864.12 OQS06584.1 - 0.0045 15.9 0.2 0.0057 15.5 0.2 1.2 1 0 0 1 1 1 1 Pilin accessory protein (PilO) PsaN PF05479.11 OQS06584.1 - 0.036 14.3 1.2 0.066 13.4 1.2 1.4 1 0 0 1 1 1 0 Photosystem I reaction centre subunit N (PSAN or PSI-N) OSCP PF00213.18 OQS06584.1 - 0.036 14.2 0.0 1.8 8.7 0.0 2.3 1 1 1 2 2 2 0 ATP synthase delta (OSCP) subunit ASF1_hist_chap PF04729.13 OQS06584.1 - 0.049 13.6 0.2 0.29 11.1 0.1 2.2 2 0 0 2 2 2 0 ASF1 like histone chaperone FXR_C1 PF16096.5 OQS06584.1 - 0.055 13.7 0.3 0.11 12.7 0.3 1.5 1 0 0 1 1 1 0 Fragile X-related 1 protein C-terminal region 2 PigN PF04987.14 OQS06584.1 - 0.086 11.7 0.0 0.25 10.1 0.0 1.6 2 0 0 2 2 2 0 Phosphatidylinositolglycan class N (PIG-N) SurA_N_3 PF13624.6 OQS06584.1 - 0.099 12.4 0.1 1.6 8.5 0.0 2.5 3 0 0 3 3 3 0 SurA N-terminal domain DUF1616 PF07760.11 OQS06584.1 - 0.1 12.0 0.0 8.3 5.7 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1616) PetG PF02529.15 OQS06584.1 - 0.12 12.3 0.7 0.19 11.6 0.7 1.3 1 0 0 1 1 1 0 Cytochrome B6-F complex subunit 5 DUF4271 PF14093.6 OQS06584.1 - 0.13 12.1 0.0 0.25 11.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4271) FixQ PF05545.11 OQS06584.1 - 2.1 8.3 4.6 0.45 10.5 0.2 2.0 2 0 0 2 2 2 0 Cbb3-type cytochrome oxidase component FixQ DUF1043 PF06295.12 OQS06584.1 - 7.7 6.5 7.3 36 4.4 3.4 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1043) PX PF00787.24 OQS06585.1 - 2.6e-21 75.7 0.5 2.8e-10 40.2 0.2 2.6 2 0 0 2 2 2 2 PX domain zf-RING_2 PF13639.6 OQS06585.1 - 1e-19 70.5 28.9 8.7e-11 42.0 10.4 3.8 3 0 0 3 3 3 2 Ring finger domain zf-C3HC4_2 PF13923.6 OQS06585.1 - 6.2e-13 48.4 31.0 7.3e-08 32.1 10.7 3.8 4 0 0 4 4 4 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 OQS06585.1 - 9.3e-13 47.8 26.1 3e-07 30.2 10.5 3.2 2 1 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 OQS06585.1 - 3.5e-12 46.4 28.9 5.3e-06 26.6 10.5 3.0 2 1 0 2 2 2 2 RING-H2 zinc finger domain zf-RING_11 PF17123.5 OQS06585.1 - 4.5e-12 45.5 17.2 9.6e-08 31.6 3.9 3.7 3 0 0 3 3 3 2 RING-like zinc finger zf-RING_5 PF14634.6 OQS06585.1 - 3.7e-08 33.2 23.9 3.7e-05 23.6 7.5 3.1 2 1 0 2 2 2 2 zinc-RING finger domain zf-C3HC4_3 PF13920.6 OQS06585.1 - 1e-07 31.7 22.3 4.7e-05 23.1 6.1 3.2 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OQS06585.1 - 1.8e-07 31.1 23.2 6.7e-06 26.0 8.0 3.5 2 1 1 3 3 3 2 RING-type zinc-finger zf-ANAPC11 PF12861.7 OQS06585.1 - 2.5e-07 30.6 12.6 0.0035 17.3 1.3 2.9 2 0 0 2 2 2 2 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.6 OQS06585.1 - 0.00022 21.0 23.3 0.0028 17.5 0.7 2.9 3 0 0 3 3 2 2 Prokaryotic RING finger family 4 zinc_ribbon_16 PF17034.5 OQS06585.1 - 0.00092 19.4 15.4 0.077 13.2 2.3 2.9 3 0 0 3 3 3 2 Zinc-ribbon like family RINGv PF12906.7 OQS06585.1 - 0.41 10.8 27.0 0.27 11.4 8.0 3.8 4 0 0 4 4 3 0 RING-variant domain FANCL_C PF11793.8 OQS06585.1 - 1.2 9.4 22.1 0.28 11.4 5.7 4.3 3 2 1 4 4 4 0 FANCL C-terminal domain Baculo_IE-1 PF05290.11 OQS06585.1 - 8.1 6.4 12.3 2.3 8.1 6.8 2.9 3 1 0 3 3 3 0 Baculovirus immediate-early protein (IE-0) Mg_trans_NIPA PF05653.14 OQS06586.1 - 1.3e-14 54.0 15.8 3e-14 52.8 15.8 1.7 1 1 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.20 OQS06586.1 - 0.00049 20.3 32.1 0.028 14.6 10.7 2.9 2 1 0 2 2 2 2 EamA-like transporter family DUF2101 PF09874.9 OQS06586.1 - 1.6 8.4 6.9 1.6 8.4 0.8 2.3 1 1 1 2 2 2 0 Predicted membrane protein (DUF2101) CrgA PF06781.12 OQS06586.1 - 2.8 8.1 5.2 1.6 8.8 0.2 2.9 3 0 0 3 3 3 0 Cell division protein CrgA zf-Nse PF11789.8 OQS06587.1 - 7e-10 38.6 4.8 1.2e-09 37.8 4.8 1.4 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4_2 PF13923.6 OQS06587.1 - 7.2e-09 35.4 9.0 1.6e-08 34.3 9.0 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 OQS06587.1 - 3.8e-08 33.1 9.4 3.8e-08 33.1 9.4 1.7 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 OQS06587.1 - 5.4e-08 32.9 9.9 1.1e-07 31.8 9.9 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.6 OQS06587.1 - 3e-07 30.3 7.8 1.8e-06 27.9 3.7 2.6 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 OQS06587.1 - 2e-05 24.4 5.3 4e-05 23.4 5.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 OQS06587.1 - 2.4e-05 24.6 11.2 2.4e-05 24.6 9.0 2.1 2 0 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.6 OQS06587.1 - 3.8e-05 23.5 10.4 0.00076 19.4 11.6 2.3 1 1 1 2 2 2 1 zinc-RING finger domain DUF3337 PF11816.8 OQS06587.1 - 0.00042 20.2 0.0 0.00066 19.6 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3337) zf-ANAPC11 PF12861.7 OQS06587.1 - 0.0007 19.6 2.9 0.0013 18.7 2.9 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger RAWUL PF16207.5 OQS06587.1 - 0.0016 19.1 0.0 0.0037 17.9 0.0 1.7 1 0 0 1 1 1 1 RAWUL domain RING finger- and WD40-associated ubiquitin-like Prok-RING_4 PF14447.6 OQS06587.1 - 0.005 16.7 9.4 0.021 14.7 3.7 2.6 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-rbx1 PF12678.7 OQS06587.1 - 0.013 15.8 8.9 0.056 13.7 8.9 2.0 1 1 0 1 1 1 0 RING-H2 zinc finger domain zf-RING_6 PF14835.6 OQS06587.1 - 0.019 14.8 3.9 0.042 13.7 3.9 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein Rad50_zn_hook PF04423.14 OQS06587.1 - 0.021 14.7 0.4 0.96 9.3 0.0 2.4 2 0 0 2 2 2 0 Rad50 zinc hook motif zf-RING_10 PF16685.5 OQS06587.1 - 0.13 12.4 3.8 0.27 11.4 3.8 1.5 1 0 0 1 1 1 0 zinc RING finger of MSL2 Zn-C2H2_12 PF18112.1 OQS06587.1 - 0.22 12.0 7.5 3.8 8.0 0.4 3.2 3 0 0 3 3 3 0 Autophagy receptor zinc finger-C2H2 domain DnaJ_CXXCXGXG PF00684.19 OQS06587.1 - 0.62 10.5 3.9 1.5 9.2 3.9 1.6 1 1 0 1 1 1 0 DnaJ central domain zinc_ribbon_9 PF14369.6 OQS06587.1 - 1.4 9.3 5.4 22 5.4 1.2 2.8 3 0 0 3 3 3 0 zinc-ribbon zf-RING_4 PF14570.6 OQS06587.1 - 1.6 8.6 11.3 75 3.2 11.9 2.6 2 1 1 3 3 3 0 RING/Ubox like zinc-binding domain DZR PF12773.7 OQS06587.1 - 2 8.5 6.6 4.5 7.4 6.6 1.6 1 0 0 1 1 1 0 Double zinc ribbon DUF1272 PF06906.11 OQS06587.1 - 2.2 8.4 7.5 0.95 9.6 2.9 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1272) zf-Di19 PF05605.12 OQS06587.1 - 2.6 8.4 7.7 15 5.9 7.7 2.2 1 1 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-C3HC4_5 PF17121.5 OQS06587.1 - 4.7 7.2 11.0 27 4.8 11.0 2.3 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C2H2_4 PF13894.6 OQS06587.1 - 6.2 7.9 10.4 6.9 7.8 0.4 3.4 3 0 0 3 3 3 0 C2H2-type zinc finger PX PF00787.24 OQS06588.1 - 4.1e-16 59.0 0.1 1.2e-07 31.7 0.1 2.3 2 0 0 2 2 2 2 PX domain Bromo_MP PF01573.16 OQS06589.1 - 0.02 14.2 0.0 0.049 13.0 0.0 1.6 1 1 0 1 1 1 0 Bromovirus movement protein DUF4436 PF14494.6 OQS06590.1 - 2.1e-19 69.8 0.1 2.6e-19 69.5 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4436) DUF4500 PF14937.6 OQS06590.1 - 1.3 9.1 5.1 7 6.7 0.2 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4500) Endonuclease_NS PF01223.23 OQS06592.1 - 6.2e-31 108.0 0.1 9.6e-31 107.3 0.1 1.2 1 0 0 1 1 1 1 DNA/RNA non-specific endonuclease PAN_4 PF14295.6 OQS06592.1 - 2.3e-28 97.8 32.3 2.8e-10 39.9 4.4 3.5 3 0 0 3 3 3 3 PAN domain PAN_1 PF00024.26 OQS06592.1 - 1.1e-16 60.5 10.9 3.3e-05 23.8 0.1 3.5 2 1 1 3 3 3 3 PAN domain MANEC PF07502.14 OQS06592.1 - 0.00031 21.0 12.5 0.4 11.0 0.5 3.4 3 0 0 3 3 3 3 MANEC domain Prok-E2_E PF14462.6 OQS06592.1 - 0.023 14.5 0.1 8.7 6.2 0.0 3.2 2 1 1 3 3 3 0 Prokaryotic E2 family E PAN_2 PF08276.11 OQS06592.1 - 0.13 12.4 26.8 0.42 10.8 3.8 4.8 5 0 0 5 5 5 0 PAN-like domain PT PF04886.12 OQS06592.1 - 1.7 8.3 78.2 1.8e+04 -17.7 78.2 3.8 1 1 0 1 1 1 0 PT repeat PAN_3 PF08277.12 OQS06592.1 - 1.9 8.3 20.5 2.7 7.9 2.2 3.5 3 0 0 3 3 3 0 PAN-like domain EGF_2 PF07974.13 OQS06593.1 - 1.2e-15 57.6 117.0 2.7e-05 24.5 6.0 10.3 9 1 0 9 9 9 7 EGF-like domain EGF PF00008.27 OQS06593.1 - 0.098 13.0 84.8 0.087 13.1 8.7 8.8 8 0 0 8 8 8 0 EGF-like domain DUF4436 PF14494.6 OQS06594.1 - 2e-17 63.3 0.8 2.6e-17 62.9 0.8 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4436) DUF2628 PF10947.8 OQS06594.1 - 4 7.8 6.6 12 6.3 2.9 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF2628) PX PF00787.24 OQS06595.1 - 5.7e-07 29.5 0.1 7.3e-07 29.2 0.1 1.1 1 0 0 1 1 1 1 PX domain Pkinase PF00069.25 OQS06596.1 - 2e-38 132.3 1.8 2.5e-15 56.6 0.0 4.1 2 1 1 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 OQS06596.1 - 4.1e-35 121.3 1.2 2.8e-12 46.5 0.3 4.2 2 1 1 3 3 3 3 Protein tyrosine kinase Ank_2 PF12796.7 OQS06596.1 - 7.9e-27 93.7 1.7 2.1e-13 50.6 0.1 4.1 2 2 2 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQS06596.1 - 1.2e-25 89.5 0.1 2.4e-09 37.5 0.0 5.1 2 2 3 5 5 5 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 OQS06596.1 - 1.4e-24 85.8 1.0 9.1e-08 32.2 0.1 4.6 3 1 1 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQS06596.1 - 1.7e-22 77.0 0.0 0.0033 17.8 0.0 7.3 7 0 0 7 7 7 4 Ankyrin repeat Ank PF00023.30 OQS06596.1 - 5.3e-18 64.6 5.3 0.001 19.4 0.0 6.6 7 0 0 7 7 7 4 Ankyrin repeat Baculo_ME53 PF06061.11 OQS06596.1 - 0.096 11.9 0.2 0.15 11.3 0.2 1.2 1 0 0 1 1 1 0 Baculoviridae ME53 zf-RanBP PF00641.18 OQS06596.1 - 2.7 7.4 5.9 1.3 8.4 2.9 1.9 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others Porin_3 PF01459.22 OQS06599.1 - 8.8e-46 156.5 0.0 1e-45 156.3 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic porin ACBP PF00887.19 OQS06600.1 - 2.1e-22 79.1 0.0 4.1e-22 78.2 0.0 1.5 1 0 0 1 1 1 1 Acyl CoA binding protein PRELI PF04707.14 OQS06600.1 - 1.9e-18 66.7 0.0 2.8e-18 66.2 0.0 1.2 1 0 0 1 1 1 1 PRELI-like family Ank_2 PF12796.7 OQS06601.1 - 5.1e-11 43.0 1.7 0.00011 22.7 0.2 2.6 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQS06601.1 - 2.4e-08 34.4 0.3 0.00099 19.6 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 OQS06601.1 - 1.5e-05 25.2 0.7 0.049 14.0 0.0 3.2 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 OQS06601.1 - 2.2e-05 24.7 0.3 12 6.5 0.0 4.4 4 0 0 4 4 4 3 Ankyrin repeat Ank_3 PF13606.6 OQS06601.1 - 2.6e-05 24.3 0.3 0.28 11.9 0.0 4.2 4 0 0 4 4 4 2 Ankyrin repeat VHL_C PF17211.3 OQS06601.1 - 0.11 12.6 0.0 0.36 10.9 0.0 1.9 1 0 0 1 1 1 0 VHL box domain AbfS_sensor PF18225.1 OQS06602.1 - 0.15 12.0 0.7 20 5.2 0.1 3.1 2 1 1 3 3 3 0 Sensor histidine kinase (AbfS) sensor domain zf-RING_UBOX PF13445.6 OQS06603.1 - 1.5e-08 34.6 12.6 5.1e-08 32.8 7.5 2.3 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4 PF00097.25 OQS06603.1 - 2.5e-08 33.6 12.2 4e-08 33.0 12.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 OQS06603.1 - 3e-08 33.4 9.2 4.6e-08 32.8 9.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 OQS06603.1 - 5.2e-08 33.1 14.3 8.7e-08 32.4 14.3 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_4 PF15227.6 OQS06603.1 - 1e-07 32.0 8.1 3.4e-07 30.3 8.3 1.8 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.6 OQS06603.1 - 4.2e-07 29.7 12.7 7.5e-07 28.9 12.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 OQS06603.1 - 9.5e-06 25.4 10.3 2.1e-05 24.3 10.3 1.5 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 OQS06603.1 - 1.6e-05 24.7 9.8 2.9e-05 23.9 9.8 1.4 1 0 0 1 1 1 1 zinc-RING finger domain U-box PF04564.15 OQS06603.1 - 5.9e-05 23.2 0.1 0.0001 22.4 0.1 1.3 1 0 0 1 1 1 1 U-box domain zf-rbx1 PF12678.7 OQS06603.1 - 0.00041 20.6 11.7 0.00088 19.5 11.7 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-Nse PF11789.8 OQS06603.1 - 0.034 14.0 7.8 0.056 13.3 7.8 1.3 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-ANAPC11 PF12861.7 OQS06603.1 - 0.073 13.1 7.8 0.13 12.4 7.8 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_11 PF17123.5 OQS06603.1 - 0.13 12.1 6.2 0.12 12.2 2.4 2.5 2 1 0 2 2 2 0 RING-like zinc finger MukE PF04288.13 OQS06603.1 - 0.17 10.8 0.3 0.24 10.3 0.3 1.1 1 0 0 1 1 1 0 MukE-like family UBZ_FAAP20 PF15750.5 OQS06603.1 - 0.27 11.2 3.9 1.1 9.2 0.1 2.9 3 0 0 3 3 3 0 Ubiquitin-binding zinc-finger zf-RING_4 PF14570.6 OQS06603.1 - 0.53 10.1 11.4 4 7.3 11.8 2.1 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain zf-RING_10 PF16685.5 OQS06603.1 - 0.54 10.4 5.5 0.97 9.6 5.5 1.4 1 0 0 1 1 1 0 zinc RING finger of MSL2 PH PF00169.29 OQS06604.1 - 1.7e-45 153.8 10.8 2.7e-11 43.9 0.1 7.0 5 3 0 5 5 5 4 PH domain PH_8 PF15409.6 OQS06604.1 - 3.4e-21 75.3 7.9 0.00015 21.9 0.0 5.4 5 0 0 5 5 5 5 Pleckstrin homology domain PH_11 PF15413.6 OQS06604.1 - 2.8e-15 56.6 24.9 5.7e-05 23.5 0.1 7.6 5 4 2 7 7 7 4 Pleckstrin homology domain PH_3 PF14593.6 OQS06604.1 - 2.7e-08 33.8 0.2 0.00052 20.1 0.0 3.7 3 1 1 4 4 4 2 PH domain Mcp5_PH PF12814.7 OQS06604.1 - 0.0025 17.9 0.2 21 5.2 0.0 5.0 5 0 0 5 5 5 1 Meiotic cell cortex C-terminal pleckstrin homology PH_9 PF15410.6 OQS06604.1 - 0.11 12.9 3.2 1.3e+02 3.0 0.0 5.3 4 2 2 6 6 6 0 Pleckstrin homology domain Ras PF00071.22 OQS06605.1 - 1.1e-57 194.1 0.3 1.4e-57 193.9 0.3 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OQS06605.1 - 2.1e-35 121.5 0.1 3.2e-35 120.9 0.1 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OQS06605.1 - 3.5e-17 62.4 0.4 4.9e-17 61.9 0.4 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 OQS06605.1 - 1.6e-06 27.6 0.1 2e-06 27.3 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 OQS06605.1 - 7.2e-06 26.1 0.1 1.7e-05 24.8 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 OQS06605.1 - 0.00025 20.6 0.3 0.0011 18.5 0.3 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 OQS06605.1 - 0.00041 19.8 0.1 0.0007 19.1 0.0 1.4 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit VirE PF05272.11 OQS06605.1 - 0.0061 16.3 0.1 0.075 12.8 0.1 2.2 2 0 0 2 2 2 1 Virulence-associated protein E AAA_16 PF13191.6 OQS06605.1 - 0.0089 16.4 0.0 0.018 15.5 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 OQS06605.1 - 0.03 14.2 0.5 0.73 9.7 0.1 2.5 1 1 1 3 3 3 0 RsgA GTPase Septin PF00735.18 OQS06605.1 - 0.047 13.0 0.0 0.079 12.2 0.0 1.3 1 0 0 1 1 1 0 Septin AAA_7 PF12775.7 OQS06605.1 - 0.098 12.2 0.0 0.18 11.3 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_5 PF07728.14 OQS06605.1 - 0.12 12.3 0.1 0.26 11.3 0.1 1.8 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AMP-binding PF00501.28 OQS06607.1 - 2e-137 458.3 0.0 9.7e-80 268.2 0.0 2.2 2 0 0 2 2 2 2 AMP-binding enzyme Thioredoxin PF00085.20 OQS06607.1 - 1.3e-26 92.6 0.2 3.5e-26 91.2 0.2 1.7 1 0 0 1 1 1 1 Thioredoxin OST3_OST6 PF04756.13 OQS06607.1 - 0.0034 16.8 0.0 0.0081 15.5 0.0 1.5 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_2 PF13098.6 OQS06607.1 - 0.016 15.6 0.1 0.038 14.4 0.1 1.7 1 0 0 1 1 1 0 Thioredoxin-like domain Thioredoxin_8 PF13905.6 OQS06607.1 - 0.024 15.0 0.1 0.072 13.4 0.1 1.8 1 0 0 1 1 1 0 Thioredoxin-like AMP-binding_C PF13193.6 OQS06607.1 - 0.052 14.5 0.2 0.15 13.0 0.2 1.9 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain Imm12 PF15560.6 OQS06607.1 - 0.061 13.3 0.8 8.1 6.4 0.0 2.5 2 0 0 2 2 2 0 Immunity protein 12 Thioredoxin_7 PF13899.6 OQS06607.1 - 0.089 13.0 0.2 0.26 11.5 0.2 1.8 1 0 0 1 1 1 0 Thioredoxin-like Pkinase_Tyr PF07714.17 OQS06608.1 - 5.5e-38 130.7 0.0 7.5e-38 130.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OQS06608.1 - 1.5e-33 116.3 0.0 2e-33 115.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain B12D PF06522.11 OQS06609.1 - 1.6e-12 47.0 0.0 2.2e-12 46.6 0.0 1.2 1 0 0 1 1 1 1 NADH-ubiquinone reductase complex 1 MLRQ subunit BrnA_antitoxin PF14384.6 OQS06609.1 - 0.017 15.6 0.0 0.027 15.0 0.0 1.4 1 1 0 1 1 1 0 BrnA antitoxin of type II toxin-antitoxin system Lipase_3 PF01764.25 OQS06610.1 - 8.7e-18 64.6 0.0 2.7e-17 62.9 0.0 2.0 1 0 0 1 1 1 1 Lipase (class 3) HEAT_EZ PF13513.6 OQS06610.1 - 2.3e-09 37.5 10.5 0.11 13.1 0.0 8.7 9 0 0 9 9 9 2 HEAT-like repeat Arm PF00514.23 OQS06610.1 - 1.3e-07 31.4 54.0 0.0062 16.5 0.7 14.8 19 0 0 19 19 19 4 Armadillo/beta-catenin-like repeat HEAT PF02985.22 OQS06610.1 - 6e-07 29.2 6.7 1.3 9.5 0.0 8.9 7 0 0 7 7 7 2 HEAT repeat HEAT_2 PF13646.6 OQS06610.1 - 3.2e-05 24.2 10.3 8.4 6.9 0.0 9.2 10 1 0 10 10 10 1 HEAT repeats Atx10homo_assoc PF09759.9 OQS06610.1 - 4e-05 23.6 18.4 2.8 8.0 0.1 8.4 7 0 0 7 7 7 2 Spinocerebellar ataxia type 10 protein domain Hydrolase_4 PF12146.8 OQS06610.1 - 0.06 12.6 0.0 0.14 11.4 0.0 1.6 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Cnd1 PF12717.7 OQS06610.1 - 0.51 10.4 27.5 0.13 12.3 0.2 7.9 9 2 1 10 10 10 0 non-SMC mitotic condensation complex subunit 1 Upf2 PF04050.14 OQS06610.1 - 1 10.1 6.5 1.1 10.0 0.6 2.8 2 1 0 2 2 2 0 Up-frameshift suppressor 2 Fib_alpha PF08702.10 OQS06610.1 - 6.9 6.8 8.7 4.8 7.4 4.1 3.0 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family ERM PF00769.19 OQS06611.1 - 0.0057 16.5 19.5 0.0057 16.5 19.5 7.4 3 3 4 7 7 7 3 Ezrin/radixin/moesin family Coiled-coil_56 PF09813.9 OQS06611.1 - 1.3 9.1 7.5 17 5.5 2.2 4.0 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 56 Methyltransf_25 PF13649.6 OQS06612.1 - 9.9e-06 26.2 0.1 0.00082 20.0 0.0 2.8 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 OQS06612.1 - 6.2e-05 22.8 0.0 0.00057 19.7 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 OQS06612.1 - 0.0004 20.2 0.0 0.0008 19.3 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OQS06612.1 - 0.0017 19.0 0.0 0.0084 16.8 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_32 PF13679.6 OQS06612.1 - 0.0025 17.8 0.0 0.0078 16.2 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 OQS06612.1 - 0.008 16.8 0.1 0.036 14.7 0.0 2.3 2 1 0 2 2 2 1 Methyltransferase domain MetW PF07021.12 OQS06612.1 - 0.038 13.6 0.0 0.63 9.6 0.0 2.7 3 0 0 3 3 3 0 Methionine biosynthesis protein MetW DUF3155 PF11352.8 OQS06613.1 - 7.8e-05 23.0 0.3 3.2 8.2 0.0 4.0 4 0 0 4 4 4 2 Protein of unknown function (DUF3155) O_anti_polymase PF01901.16 OQS06613.1 - 0.00044 19.6 0.0 6 6.0 0.0 3.9 4 0 0 4 4 4 2 Putative O-antigen polymerase Glyco_hydro_14 PF01373.17 OQS06613.1 - 0.0045 16.0 0.1 0.054 12.4 0.0 2.4 2 0 0 2 2 2 1 Glycosyl hydrolase family 14 MID_MedPIWI PF18296.1 OQS06613.1 - 0.1 12.4 15.8 4.5 7.0 0.7 5.4 4 3 0 4 4 4 0 MID domain of medPIWI zf-CCCH PF00642.24 OQS06613.1 - 0.68 9.9 20.7 0.44 10.5 1.1 4.8 6 0 0 6 6 6 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) DHC PF09626.10 OQS06613.1 - 3.3 8.6 8.2 10 7.0 1.2 3.3 3 0 0 3 3 3 0 Dihaem cytochrome c Exo_endo_phos PF03372.23 OQS06614.1 - 1.7e-18 67.0 0.0 6.1e-18 65.2 0.0 1.8 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.6 OQS06614.1 - 0.11 12.4 0.4 6.1 6.7 0.0 2.9 2 1 1 3 3 3 0 Endonuclease-reverse transcriptase RRM_1 PF00076.22 OQS06615.1 - 5.8e-17 61.3 0.0 9.3e-17 60.6 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 OQS06615.1 - 0.048 13.8 0.0 0.11 12.6 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif FHA PF00498.26 OQS06616.1 - 2.1e-12 47.2 0.0 4.6e-12 46.1 0.0 1.6 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 OQS06616.1 - 7.4e-06 26.2 0.0 2.2e-05 24.7 0.0 1.7 2 0 0 2 2 2 1 Inner membrane component of T3SS, cytoplasmic domain Sec6 PF06046.13 OQS06616.1 - 0.05 12.0 0.2 0.063 11.6 0.2 1.1 1 0 0 1 1 1 0 Exocyst complex component Sec6 PTP_tm PF18861.1 OQS06616.1 - 0.11 12.4 0.5 0.26 11.2 0.4 1.8 2 0 0 2 2 2 0 Transmembrane domain of protein tyrosine phosphatase, receptor type J YEATS PF03366.16 OQS06617.1 - 6.1e-29 99.8 0.0 9.6e-29 99.2 0.0 1.3 1 0 0 1 1 1 1 YEATS family BTB_2 PF02214.22 OQS06618.1 - 1.3e-12 47.9 0.0 2.4e-12 47.1 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain DUF3081 PF11280.8 OQS06618.1 - 0.023 14.5 0.1 0.24 11.3 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3081) DUF1310 PF07006.11 OQS06618.1 - 0.032 14.2 0.1 0.052 13.5 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1310) BTB_3 PF16017.5 OQS06618.1 - 0.063 13.4 0.0 0.14 12.3 0.0 1.5 1 0 0 1 1 1 0 BTB/POZ domain BTB PF00651.31 OQS06618.1 - 0.077 13.2 0.0 0.16 12.2 0.0 1.4 1 0 0 1 1 1 0 BTB/POZ domain DUF543 PF04418.12 OQS06619.1 - 8.1e-21 73.8 0.8 9.1e-21 73.6 0.8 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF543) Myc_target_1 PF15179.6 OQS06619.1 - 0.05 13.5 0.0 0.063 13.2 0.0 1.1 1 0 0 1 1 1 0 Myc target protein 1 DUF3767 PF12597.8 OQS06619.1 - 0.31 10.9 1.8 0.54 10.1 1.8 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3767) UAA PF08449.11 OQS06620.1 - 2.5e-48 164.8 18.4 4.2e-48 164.1 18.4 1.3 1 1 0 1 1 1 1 UAA transporter family EamA PF00892.20 OQS06620.1 - 2.6e-06 27.6 26.0 2.7e-06 27.6 9.6 2.1 2 0 0 2 2 2 2 EamA-like transporter family COPI_assoc PF08507.10 OQS06620.1 - 0.00051 20.1 4.9 0.00051 20.1 4.9 2.8 2 1 0 3 3 3 1 COPI associated protein TPT PF03151.16 OQS06620.1 - 0.0023 17.3 0.9 0.0023 17.3 0.9 2.1 2 0 0 2 2 2 1 Triose-phosphate Transporter family DUF1129 PF06570.11 OQS06620.1 - 1.6 8.2 13.1 0.075 12.5 1.9 3.4 1 1 1 3 3 3 0 Protein of unknown function (DUF1129) Ribosomal_L9_N PF01281.19 OQS06621.1 - 7e-20 70.3 6.1 9.1e-20 70.0 1.7 2.7 3 0 0 3 3 3 1 Ribosomal protein L9, N-terminal domain Ribosomal_L9_C PF03948.14 OQS06621.1 - 1.3e-08 35.2 0.7 1.3e-08 35.2 0.7 1.8 2 0 0 2 2 2 1 Ribosomal protein L9, C-terminal domain DUF531 PF04407.12 OQS06621.1 - 0.0016 18.6 0.1 0.0028 17.7 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF531) Microvir_H PF04687.12 OQS06621.1 - 0.037 13.4 0.8 0.081 12.3 0.3 1.7 2 0 0 2 2 2 0 Microvirus H protein (pilot protein) Ank_2 PF12796.7 OQS06622.1 - 6.7e-53 177.2 21.2 4.5e-17 62.4 0.8 3.5 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OQS06622.1 - 1.3e-32 108.1 4.6 1.7e-06 27.9 0.0 6.0 5 1 1 6 6 6 5 Ankyrin repeat Ank_4 PF13637.6 OQS06622.1 - 1.5e-32 111.6 5.3 8.7e-14 51.7 0.0 4.9 3 2 2 5 5 5 5 Ankyrin repeats (many copies) Ank PF00023.30 OQS06622.1 - 1.4e-31 107.5 8.1 2e-07 31.1 0.1 6.2 5 1 1 6 6 6 5 Ankyrin repeat Ank_5 PF13857.6 OQS06622.1 - 1.6e-28 98.4 6.4 1.5e-10 41.1 0.1 5.1 1 1 4 5 5 5 4 Ankyrin repeats (many copies) GATase_7 PF13537.6 OQS06622.1 - 0.028 14.3 0.0 0.37 10.7 0.0 2.6 1 1 2 3 3 3 0 Glutamine amidotransferase domain VWA_3_C PF18571.1 OQS06622.1 - 0.14 12.0 4.7 5 7.1 0.1 4.1 5 0 0 5 5 5 0 von Willebrand factor type A C-terminal domain VPR PF00522.18 OQS06624.1 - 0.075 13.1 0.0 0.081 13.0 0.0 1.1 1 0 0 1 1 1 0 VPR/VPX protein Dynein_light PF01221.18 OQS06624.1 - 0.26 11.6 1.0 0.31 11.4 1.0 1.1 1 0 0 1 1 1 0 Dynein light chain type 1 Amino_oxidase PF01593.24 OQS06625.1 - 4.7e-17 62.4 0.1 3.7e-16 59.4 0.1 2.2 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 OQS06625.1 - 7e-12 45.4 0.8 7e-12 45.4 0.8 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 OQS06625.1 - 1.2e-07 31.1 2.1 6.7e-05 22.1 1.8 2.2 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.24 OQS06625.1 - 1.3e-07 31.5 1.0 0.0011 18.6 0.6 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase HI0933_like PF03486.14 OQS06625.1 - 2.1e-06 26.7 1.0 0.015 14.0 0.0 2.2 2 0 0 2 2 2 2 HI0933-like protein GIDA PF01134.22 OQS06625.1 - 3.4e-06 26.4 0.8 0.054 12.6 0.2 2.3 2 0 0 2 2 2 2 Glucose inhibited division protein A FAD_oxidored PF12831.7 OQS06625.1 - 6.7e-06 25.7 0.4 0.00025 20.5 0.7 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 OQS06625.1 - 1.2e-05 24.8 0.0 0.0029 16.9 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase GDI PF00996.18 OQS06625.1 - 0.00052 18.7 0.0 0.095 11.2 0.0 2.1 2 0 0 2 2 2 2 GDP dissociation inhibitor Thi4 PF01946.17 OQS06625.1 - 0.0019 17.5 0.1 0.0041 16.4 0.1 1.5 1 0 0 1 1 1 1 Thi4 family FAD_binding_3 PF01494.19 OQS06625.1 - 0.0024 17.2 1.1 0.0042 16.4 1.1 1.4 1 0 0 1 1 1 1 FAD binding domain AlaDh_PNT_C PF01262.21 OQS06625.1 - 0.009 15.3 0.0 0.015 14.6 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox PF00070.27 OQS06625.1 - 0.0092 16.5 1.2 0.11 13.1 0.3 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 OQS06625.1 - 0.026 13.6 0.1 3.6 6.6 0.0 2.2 2 0 0 2 2 2 0 Lycopene cyclase protein GMC_oxred_N PF00732.19 OQS06625.1 - 0.041 13.2 0.3 0.093 12.1 0.0 1.7 2 0 0 2 2 2 0 GMC oxidoreductase Pyr_redox_3 PF13738.6 OQS06625.1 - 0.073 12.3 0.4 0.46 9.7 0.1 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase IQ PF00612.27 OQS06626.1 - 8.1e-09 34.5 2.7 0.00047 19.7 0.1 2.8 2 0 0 2 2 2 2 IQ calmodulin-binding motif Exo_endo_phos PF03372.23 OQS06626.1 - 4.4e-07 29.7 0.0 1.1e-06 28.4 0.0 1.7 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DUF3506 PF12014.8 OQS06626.1 - 0.11 12.5 0.5 0.55 10.2 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3506) Ank_2 PF12796.7 OQS06628.1 - 2.4e-33 114.6 2.0 8.6e-18 64.7 0.4 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQS06628.1 - 6.5e-25 87.2 0.0 2e-15 56.9 0.0 2.2 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 OQS06628.1 - 2.7e-23 81.3 5.5 4.5e-06 26.9 0.5 4.1 4 0 0 4 4 4 4 Ankyrin repeat Ank_5 PF13857.6 OQS06628.1 - 2.7e-22 78.6 3.1 1.6e-09 37.8 0.1 2.9 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQS06628.1 - 2.3e-21 73.6 0.1 2.6e-05 24.2 0.0 4.1 4 0 0 4 4 4 3 Ankyrin repeat CCDC66 PF15236.6 OQS06629.1 - 0.033 14.0 55.0 0.037 13.9 32.2 3.6 3 0 0 3 3 3 0 Coiled-coil domain-containing protein 66 PK PF00224.21 OQS06630.1 - 9.6e-130 432.5 0.1 1.4e-129 431.9 0.1 1.2 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.16 OQS06630.1 - 3.2e-28 98.3 3.4 6.9e-28 97.2 3.4 1.6 1 0 0 1 1 1 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.14 OQS06630.1 - 0.00015 20.9 1.2 0.0005 19.3 0.2 2.2 2 1 1 3 3 3 1 HpcH/HpaI aldolase/citrate lyase family tRNA-synt_2b PF00587.25 OQS06631.1 - 5.9e-29 101.3 0.0 1.2e-28 100.3 0.0 1.5 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 OQS06631.1 - 2.6e-11 43.5 0.0 4.7e-11 42.7 0.0 1.5 1 0 0 1 1 1 1 Anticodon binding domain Peptidase_M17_N PF02789.17 OQS06631.1 - 0.0022 17.8 0.0 0.0048 16.8 0.0 1.5 1 0 0 1 1 1 1 Cytosol aminopeptidase family, N-terminal domain MMR_HSR1_Xtn PF16897.5 OQS06631.1 - 0.13 12.3 0.2 0.33 11.0 0.3 1.7 1 1 0 1 1 1 0 C-terminal region of MMR_HSR1 domain GRAM PF02893.20 OQS06632.1 - 5e-06 26.4 0.0 6.9e-06 25.9 0.0 1.2 1 0 0 1 1 1 1 GRAM domain Vps36_ESCRT-II PF11605.8 OQS06632.1 - 0.001 19.2 0.0 0.002 18.3 0.0 1.5 1 0 0 1 1 1 1 Vacuolar protein sorting protein 36 Vps36 bPH_3 PF14470.6 OQS06632.1 - 0.049 14.0 0.1 0.081 13.3 0.0 1.5 2 0 0 2 2 2 0 Bacterial PH domain Tim17 PF02466.19 OQS06633.1 - 0.00016 22.0 2.0 0.0019 18.5 0.1 2.5 2 0 0 2 2 2 1 Tim17/Tim22/Tim23/Pmp24 family TMEM135_C_rich PF15982.5 OQS06633.1 - 0.0034 18.0 1.6 0.069 13.8 1.6 2.5 1 1 0 1 1 1 1 N-terminal cysteine-rich region of Transmembrane protein 135 DASH_Ask1 PF08655.10 OQS06633.1 - 0.005 16.7 0.0 0.013 15.4 0.0 1.7 1 0 0 1 1 1 1 DASH complex subunit Ask1 cNMP_binding PF00027.29 OQS06634.1 - 4.3e-11 42.7 0.0 7.5e-11 42.0 0.0 1.4 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain STAS PF01740.21 OQS06634.1 - 9.7e-07 28.4 0.3 2.3e-06 27.2 0.0 1.8 2 0 0 2 2 2 1 STAS domain RecA PF00154.21 OQS06635.1 - 7.3e-120 399.3 4.1 1.5e-114 381.9 2.4 2.1 1 1 1 2 2 2 2 recA bacterial DNA recombination protein Rad51 PF08423.11 OQS06635.1 - 7.9e-10 38.4 0.5 1.8e-08 34.0 0.5 2.1 1 1 0 1 1 1 1 Rad51 ATPase PF06745.13 OQS06635.1 - 8.2e-09 35.1 0.6 2.5e-07 30.3 0.6 2.8 2 1 0 2 2 2 1 KaiC ATPase_2 PF01637.18 OQS06635.1 - 1.9e-05 24.7 0.0 3.2e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_24 PF13479.6 OQS06635.1 - 7e-05 22.6 0.0 0.00011 22.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.6 OQS06635.1 - 0.0007 19.2 0.4 0.0069 16.0 0.4 2.2 1 1 0 1 1 1 1 AAA domain AAA PF00004.29 OQS06635.1 - 0.0034 17.8 0.0 0.0079 16.6 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) CobU PF02283.16 OQS06635.1 - 0.0069 16.0 0.0 0.014 14.9 0.0 1.5 1 1 0 1 1 1 1 Cobinamide kinase / cobinamide phosphate guanyltransferase AAA_16 PF13191.6 OQS06635.1 - 0.007 16.8 0.0 0.016 15.6 0.0 1.6 2 0 0 2 2 2 1 AAA ATPase domain TK PF00265.18 OQS06635.1 - 0.01 15.7 0.0 0.015 15.2 0.0 1.3 1 0 0 1 1 1 0 Thymidine kinase AAA_14 PF13173.6 OQS06635.1 - 0.013 15.5 0.0 0.33 11.0 0.0 2.4 1 1 1 2 2 2 0 AAA domain AAA_35 PF14516.6 OQS06635.1 - 0.02 13.7 0.0 0.036 12.9 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain DnaB_C PF03796.15 OQS06635.1 - 0.021 14.2 0.2 0.2 11.0 0.0 2.1 1 1 1 2 2 2 0 DnaB-like helicase C terminal domain ABC_tran PF00005.27 OQS06635.1 - 0.071 13.6 0.0 0.13 12.7 0.0 1.6 1 1 0 1 1 1 0 ABC transporter MobB PF03205.14 OQS06635.1 - 0.071 13.0 0.0 0.21 11.5 0.0 1.8 1 1 1 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Rad51 PF08423.11 OQS06637.1 - 2.7e-121 403.7 0.1 4e-121 403.1 0.1 1.3 1 0 0 1 1 1 1 Rad51 Peptidase_S8 PF00082.22 OQS06637.1 - 1e-41 143.1 2.9 2e-41 142.2 2.9 1.5 1 0 0 1 1 1 1 Subtilase family RecA PF00154.21 OQS06637.1 - 1.5e-11 44.3 0.1 2.6e-11 43.5 0.1 1.3 1 0 0 1 1 1 1 recA bacterial DNA recombination protein AAA_25 PF13481.6 OQS06637.1 - 2.2e-09 37.2 0.1 4.8e-09 36.1 0.1 1.5 1 0 0 1 1 1 1 AAA domain HHH_5 PF14520.6 OQS06637.1 - 1.5e-08 35.1 1.1 4.5e-08 33.6 0.3 2.3 2 0 0 2 2 1 1 Helix-hairpin-helix domain ATPase PF06745.13 OQS06637.1 - 1e-06 28.3 0.0 2.3e-06 27.1 0.0 1.6 1 0 0 1 1 1 1 KaiC DnaB_C PF03796.15 OQS06637.1 - 0.00044 19.7 0.9 0.0027 17.1 0.0 2.5 3 0 0 3 3 3 1 DnaB-like helicase C terminal domain AAA_24 PF13479.6 OQS06637.1 - 0.0013 18.5 0.0 0.003 17.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.6 OQS06637.1 - 0.065 13.5 0.1 0.21 11.8 0.1 1.8 1 0 0 1 1 1 0 AAA domain Nup96 PF12110.8 OQS06637.1 - 0.096 11.8 1.7 0.14 11.2 1.7 1.2 1 0 0 1 1 1 0 Nuclear protein 96 CspB_prodomain PF18425.1 OQS06637.1 - 0.56 10.3 2.0 13 5.9 0.2 2.5 1 1 1 2 2 2 0 Csp protease B prodomain Defensin_1 PF00323.19 OQS06638.1 - 3.3 8.4 17.2 0.39 11.3 1.0 3.2 3 0 0 3 3 3 0 Mammalian defensin UPF0506 PF11703.8 OQS06638.1 - 9.2 6.7 15.0 5.5 7.4 2.6 2.9 1 1 2 3 3 3 0 UPF0506 HDA2-3 PF11496.8 OQS06639.1 - 0.12 11.5 0.2 0.16 11.1 0.2 1.1 1 0 0 1 1 1 0 Class II histone deacetylase complex subunits 2 and 3 NCKAP5 PF15246.6 OQS06641.1 - 0.17 11.5 4.4 0.18 11.4 3.1 1.6 1 1 0 1 1 1 0 Nck-associated protein 5, Peripheral clock protein FapA PF03961.13 OQS06641.1 - 0.57 8.7 8.5 0.78 8.3 8.5 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A MRPL52 PF18699.1 OQS06642.1 - 0.00011 22.3 0.1 0.00018 21.6 0.1 1.2 1 0 0 1 1 1 1 Mitoribosomal protein mL52 IRK_N PF08466.10 OQS06642.1 - 0.11 12.7 0.0 0.27 11.4 0.0 1.7 1 0 0 1 1 1 0 Inward rectifier potassium channel N-terminal DUF4209 PF13910.6 OQS06643.1 - 4.9e-20 71.5 0.8 6.9e-17 61.5 0.1 3.0 2 0 0 2 2 2 2 Domain of unknown function (DUF4209) LTV PF04180.14 OQS06644.1 - 2.5e-28 99.9 25.9 3.4e-18 66.6 11.0 3.1 1 1 1 2 2 2 2 Low temperature viability protein Acetyltransf_7 PF13508.7 OQS06645.1 - 0.00016 22.0 0.0 0.00037 20.8 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 OQS06645.1 - 0.0011 19.1 0.1 0.0024 18.0 0.1 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 OQS06645.1 - 0.0025 18.0 0.0 0.0057 16.9 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_13 PF13880.6 OQS06645.1 - 0.028 14.4 0.0 0.059 13.4 0.0 1.5 1 0 0 1 1 1 0 ESCO1/2 acetyl-transferase zf-RING_2 PF13639.6 OQS06646.1 - 1.1e-09 38.4 14.2 1.1e-09 38.4 14.2 2.5 2 0 0 2 2 2 1 Ring finger domain PX PF00787.24 OQS06646.1 - 5.3e-08 32.8 0.2 1.5e-07 31.4 0.2 1.7 1 0 0 1 1 1 1 PX domain zf-rbx1 PF12678.7 OQS06646.1 - 1.4e-06 28.5 16.0 1.4e-06 28.5 16.0 2.1 2 1 0 2 2 2 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 OQS06646.1 - 1.8e-06 27.7 13.6 6.3e-06 26.0 13.6 2.0 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 OQS06646.1 - 2.3e-06 27.2 11.2 8.7e-06 25.4 11.2 2.1 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 OQS06646.1 - 2.3e-05 24.1 13.7 0.00018 21.2 13.7 2.4 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OQS06646.1 - 0.0004 20.3 11.2 0.0013 18.6 11.2 2.0 1 0 0 1 1 1 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 OQS06646.1 - 0.00046 20.2 9.2 0.00046 20.2 9.2 2.1 2 1 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.6 OQS06646.1 - 0.0011 18.8 9.6 0.0011 18.8 9.6 2.4 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OQS06646.1 - 0.0015 18.5 12.3 0.0015 18.5 12.3 2.3 2 0 0 2 2 2 1 RING-type zinc-finger FANCL_C PF11793.8 OQS06646.1 - 0.038 14.2 11.7 0.24 11.6 11.7 2.2 1 1 0 1 1 1 0 FANCL C-terminal domain PRA1 PF03208.19 OQS06646.1 - 0.078 12.6 0.2 3.5 7.2 0.1 2.2 2 0 0 2 2 2 0 PRA1 family protein Prok-RING_4 PF14447.6 OQS06646.1 - 0.11 12.4 13.5 1.1 9.2 13.3 2.6 2 1 1 3 3 3 0 Prokaryotic RING finger family 4 zf-RING_6 PF14835.6 OQS06646.1 - 0.14 12.0 2.6 0.53 10.2 2.6 2.0 1 1 0 1 1 1 0 zf-RING of BARD1-type protein RINGv PF12906.7 OQS06646.1 - 1.9 8.7 11.6 5.1 7.3 11.6 1.8 1 1 0 1 1 1 0 RING-variant domain PX PF00787.24 OQS06648.1 - 6.8e-12 45.4 2.1 1.2e-11 44.5 2.1 1.4 1 0 0 1 1 1 1 PX domain zf-rbx1 PF12678.7 OQS06648.1 - 1.2e-11 44.7 3.8 3.4e-11 43.2 3.8 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 OQS06648.1 - 1.7e-11 44.3 4.5 1.7e-11 44.3 4.5 2.1 2 0 0 2 2 1 1 Ring finger domain zf-C3HC4 PF00097.25 OQS06648.1 - 8.7e-08 31.9 3.0 2.5e-07 30.5 3.0 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 OQS06648.1 - 3.6e-07 29.8 1.1 1.2e-06 28.2 1.1 2.0 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_UBOX PF13445.6 OQS06648.1 - 6.2e-06 26.1 5.0 2.9e-05 24.0 4.4 2.4 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 OQS06648.1 - 6.9e-06 25.8 2.3 1.8e-05 24.5 2.3 1.8 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 OQS06648.1 - 1.8e-05 24.7 4.1 4.8e-05 23.3 3.5 1.9 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_2 PF13923.6 OQS06648.1 - 2.7e-05 23.9 7.6 2.7e-05 23.9 7.6 2.2 2 1 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OQS06648.1 - 5e-05 23.2 2.6 0.00014 21.8 2.6 1.8 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 OQS06648.1 - 0.00016 21.4 3.6 0.001 18.9 3.6 2.2 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 FANCL_C PF11793.8 OQS06648.1 - 0.0021 18.2 2.6 0.0097 16.1 2.6 2.2 1 1 0 1 1 1 1 FANCL C-terminal domain DUF2714 PF10896.8 OQS06648.1 - 0.0071 16.4 0.3 0.011 15.8 0.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2714) zf-C3HC4_4 PF15227.6 OQS06648.1 - 0.0085 16.2 1.1 0.0085 16.2 1.1 2.3 2 1 0 2 2 2 1 zinc finger of C3HC4-type, RING Zn-ribbon_8 PF09723.10 OQS06648.1 - 0.035 14.2 1.7 0.089 12.9 0.5 2.3 2 0 0 2 2 2 0 Zinc ribbon domain zinc_ribbon_16 PF17034.5 OQS06648.1 - 0.042 14.1 0.7 0.042 14.1 0.7 2.1 2 0 0 2 2 2 0 Zinc-ribbon like family zf-Nse PF11789.8 OQS06648.1 - 0.05 13.4 4.8 0.14 12.0 2.0 2.5 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit zf-C3H2C3 PF17122.5 OQS06648.1 - 0.057 13.5 3.9 0.2 11.7 3.9 2.1 1 0 0 1 1 1 0 Zinc-finger Zn_ribbon_17 PF17120.5 OQS06648.1 - 0.068 12.8 5.7 0.59 9.8 5.7 2.3 1 1 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-RING-like PF08746.11 OQS06648.1 - 1.3 9.4 4.3 3.7 7.9 4.3 1.9 1 1 0 1 1 1 0 RING-like domain RINGv PF12906.7 OQS06648.1 - 3.6 7.8 7.3 0.89 9.7 2.9 2.4 2 1 0 2 2 2 0 RING-variant domain LRR_6 PF13516.6 OQS06651.1 - 6e-16 57.1 10.4 0.0023 17.8 0.0 7.4 9 0 0 9 9 9 5 Leucine Rich repeat LRR_4 PF12799.7 OQS06651.1 - 3.5e-06 27.3 7.7 3.8 8.1 0.1 7.1 6 1 2 8 8 8 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 OQS06651.1 - 0.0054 16.5 9.2 2.6 7.9 0.3 6.0 4 2 1 5 5 5 3 Leucine rich repeat LRR_8 PF13855.6 OQS06652.1 - 0.4 10.5 5.4 1.6 8.5 0.8 3.9 4 1 0 4 4 4 0 Leucine rich repeat LRR_6 PF13516.6 OQS06652.1 - 0.54 10.5 12.0 1.1 9.4 0.0 4.7 5 1 0 5 5 5 0 Leucine Rich repeat Ank_4 PF13637.6 OQS06654.1 - 9e-05 23.0 0.1 0.0009 19.8 0.0 2.2 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 OQS06654.1 - 0.00041 20.6 0.1 1.5 9.2 0.0 2.8 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 OQS06654.1 - 0.0018 18.8 0.1 0.0026 18.3 0.1 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Rotavirus_VP7 PF05868.11 OQS06654.1 - 0.032 13.6 0.0 0.038 13.4 0.0 1.2 1 0 0 1 1 1 0 Rotavirus major outer capsid protein VP7 Ank_3 PF13606.6 OQS06654.1 - 0.11 13.1 0.0 0.85 10.4 0.0 2.4 2 0 0 2 2 2 0 Ankyrin repeat bZIP_1 PF00170.21 OQS06655.1 - 5.7e-09 35.9 5.0 5.7e-09 35.9 5.0 1.7 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.15 OQS06655.1 - 2.5e-07 30.7 7.5 2.5e-07 30.7 7.5 1.8 2 0 0 2 2 2 1 Basic region leucine zipper Exo_endo_phos PF03372.23 OQS06656.1 - 6.1e-20 71.7 0.0 8.1e-20 71.3 0.0 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.6 OQS06656.1 - 0.0087 15.9 0.1 0.045 13.6 0.1 2.1 1 1 0 1 1 1 1 Endonuclease-reverse transcriptase ABC_membrane_2 PF06472.15 OQS06657.1 - 2e-79 266.8 3.8 2e-79 266.8 3.8 2.6 2 0 0 2 2 2 1 ABC transporter transmembrane region 2 ABC_tran PF00005.27 OQS06657.1 - 6.2e-16 59.2 0.0 1.3e-15 58.1 0.0 1.6 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 OQS06657.1 - 0.0017 17.8 0.3 0.75 9.2 0.2 2.5 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 OQS06657.1 - 0.0064 16.3 0.0 0.012 15.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 OQS06657.1 - 0.039 14.4 0.1 0.12 12.8 0.0 1.7 2 0 0 2 2 2 0 AAA domain TTC5_OB PF16669.5 OQS06657.1 - 0.07 12.8 0.0 6.2 6.5 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat protein 5 OB fold domain Ninjurin PF04923.12 OQS06657.1 - 5.4 7.0 6.0 1.3 9.0 0.5 2.9 3 0 0 3 3 3 0 Ninjurin TFIID_30kDa PF03540.13 OQS06658.1 - 9.9e-20 70.2 0.3 1.5e-19 69.6 0.3 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID 23-30kDa subunit EF-hand_14 PF17959.1 OQS06658.1 - 0.16 12.3 0.0 1.3 9.5 0.0 2.1 2 0 0 2 2 2 0 EF-hand domain TTL PF03133.15 OQS06659.1 - 8.6e-76 254.9 0.4 2.7e-75 253.2 0.0 1.9 2 0 0 2 2 2 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 OQS06659.1 - 3.5e-06 26.4 0.1 0.00019 20.8 0.0 3.3 3 1 1 4 4 4 1 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 OQS06659.1 - 0.08 12.2 0.0 0.33 10.1 0.0 2.0 2 0 0 2 2 2 0 Sugar-transfer associated ATP-grasp Cut12 PF11500.8 OQS06659.1 - 0.095 12.6 11.9 0.21 11.5 10.8 2.1 1 1 0 1 1 1 0 Spindle pole body formation-associated protein CagX PF03524.15 OQS06659.1 - 0.13 12.0 0.1 0.13 12.0 0.1 2.1 2 0 0 2 2 2 0 Conjugal transfer protein FAM60A PF15396.6 OQS06659.1 - 0.34 10.9 11.7 0.083 12.9 7.8 2.0 2 0 0 2 2 2 0 Protein Family FAM60A ATP-synt_E PF05680.12 OQS06659.1 - 3.8 7.9 9.6 15 6.0 9.6 2.0 1 0 0 1 1 1 0 ATP synthase E chain Miga PF10265.9 OQS06659.1 - 7.8 5.3 10.7 15 4.4 10.7 1.5 1 0 0 1 1 1 0 Mitoguardin PLA2G12 PF06951.11 OQS06660.1 - 2.2e-18 66.8 13.2 3.2e-18 66.3 13.2 1.2 1 0 0 1 1 1 1 Group XII secretory phospholipase A2 precursor (PLA2G12) CBS PF00571.28 OQS06661.1 - 5.4e-20 71.6 0.1 4.5e-10 39.8 0.2 2.6 2 0 0 2 2 2 2 CBS domain LRR_9 PF14580.6 OQS06661.1 - 9.6e-17 61.0 8.8 1.3e-14 54.1 2.3 3.0 2 1 1 3 3 3 2 Leucine-rich repeat LRR_4 PF12799.7 OQS06661.1 - 2.3e-14 53.3 28.5 0.00013 22.2 0.3 6.4 3 2 4 7 7 7 6 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 OQS06661.1 - 3.1e-08 33.3 25.3 0.015 15.1 1.5 5.4 3 1 2 5 5 5 4 Leucine rich repeat LRR_6 PF13516.6 OQS06661.1 - 0.00029 20.6 21.8 2.2 8.5 0.1 8.2 8 0 0 8 8 8 2 Leucine Rich repeat PRC PF05239.16 OQS06661.1 - 0.086 12.9 0.3 0.2 11.7 0.1 1.7 2 0 0 2 2 2 0 PRC-barrel domain LRR_1 PF00560.33 OQS06661.1 - 0.25 12.0 20.4 2.3 9.1 0.2 6.9 6 1 0 6 6 6 0 Leucine Rich Repeat PhoLip_ATPase_C PF16212.5 OQS06662.1 - 4.8e-61 206.7 21.5 4.8e-61 206.7 21.5 2.9 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 OQS06662.1 - 1.2e-18 66.5 1.7 3.5e-18 65.0 1.7 1.7 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 OQS06662.1 - 4.1e-11 43.6 0.2 0.00019 21.8 0.1 3.1 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 OQS06662.1 - 2.7e-06 27.3 0.1 1.1e-05 25.4 0.0 2.0 2 0 0 2 2 2 1 Cation transport ATPase (P-type) E1-E2_ATPase PF00122.20 OQS06662.1 - 0.0051 16.4 0.9 0.0051 16.4 0.9 2.9 2 1 0 2 2 2 1 E1-E2 ATPase Hydrolase_3 PF08282.12 OQS06662.1 - 0.016 15.0 0.1 0.034 13.9 0.1 1.5 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase GAS PF13851.6 OQS06664.1 - 0.002 17.5 71.0 0.031 13.6 8.9 4.3 1 1 3 4 4 4 3 Growth-arrest specific micro-tubule binding PV-1 PF06637.11 OQS06664.1 - 0.4 9.4 35.6 0.63 8.8 14.2 2.6 1 1 1 2 2 2 0 PV-1 protein (PLVAP) ATG16 PF08614.11 OQS06664.1 - 0.46 10.7 56.5 0.06 13.6 17.1 4.0 1 1 3 4 4 4 0 Autophagy protein 16 (ATG16) DUF745 PF05335.13 OQS06664.1 - 2.5 7.8 39.8 0.025 14.3 11.3 3.3 1 1 1 3 3 3 0 Protein of unknown function (DUF745) DUF4486 PF14858.6 OQS06665.1 - 4.2e-10 38.7 9.0 2.3e-08 33.0 0.3 2.9 3 0 0 3 3 3 2 Domain of unknown function (DUF4486) RasGAP_C PF03836.15 OQS06665.1 - 0.23 11.6 5.3 0.63 10.2 5.3 1.7 1 0 0 1 1 1 0 RasGAP C-terminus ASH PF15780.5 OQS06666.1 - 1.7e-06 28.2 0.6 0.0011 19.1 0.1 3.6 3 0 0 3 3 3 1 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin TMEM131_like PF12371.8 OQS06666.1 - 3.1e-05 24.1 1.2 0.048 13.9 0.1 3.5 3 0 0 3 3 3 2 Transmembrane protein 131-like Motile_Sperm PF00635.26 OQS06666.1 - 0.00013 21.8 0.4 0.00063 19.6 0.2 2.3 2 0 0 2 2 2 1 MSP (Major sperm protein) domain C12orf66_like PF09404.10 OQS06669.1 - 1.2e-16 60.6 6.9 1.2e-06 27.7 0.4 4.1 4 0 0 4 4 4 4 KICSTOR complex C12orf66 like GCV_T PF01571.21 OQS06670.1 - 2.3e-10 40.3 0.0 4.5e-10 39.3 0.0 1.4 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain MMR_HSR1 PF01926.23 OQS06671.1 - 3.6e-12 46.4 0.1 6e-06 26.3 0.0 2.9 3 0 0 3 3 3 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 OQS06671.1 - 3.2e-06 27.2 2.5 1.1e-05 25.4 2.5 1.9 1 1 0 1 1 1 1 RsgA GTPase GTP_EFTU PF00009.27 OQS06671.1 - 1.3e-05 24.8 0.3 0.019 14.5 0.1 3.1 1 1 1 2 2 2 2 Elongation factor Tu GTP binding domain MeaB PF03308.16 OQS06671.1 - 0.00013 21.1 0.1 0.0037 16.3 0.2 2.4 1 1 1 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB Dynamin_N PF00350.23 OQS06671.1 - 0.00013 22.1 3.5 0.00039 20.5 1.9 2.5 2 1 0 2 2 2 1 Dynamin family FeoB_N PF02421.18 OQS06671.1 - 0.00023 20.7 0.3 0.081 12.5 0.0 3.3 3 0 0 3 3 3 1 Ferrous iron transport protein B AAA_15 PF13175.6 OQS06671.1 - 0.00099 18.9 3.4 0.00099 18.9 3.4 1.9 2 0 0 2 2 2 1 AAA ATPase domain FtsK_SpoIIIE PF01580.18 OQS06671.1 - 0.011 15.1 0.1 0.018 14.4 0.1 1.2 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_29 PF13555.6 OQS06671.1 - 0.024 14.4 0.0 0.054 13.3 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Roc PF08477.13 OQS06671.1 - 0.027 14.7 0.0 2.5 8.4 0.0 2.5 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase T2SSE PF00437.20 OQS06671.1 - 0.048 12.7 0.1 0.12 11.4 0.0 1.6 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_14 PF13173.6 OQS06671.1 - 0.085 12.9 0.0 0.2 11.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 OQS06671.1 - 0.086 13.3 0.0 0.23 12.0 0.0 1.7 1 0 0 1 1 1 0 ABC transporter RNA_helicase PF00910.22 OQS06671.1 - 0.098 13.1 0.0 0.23 11.8 0.0 1.6 1 0 0 1 1 1 0 RNA helicase ATP_bind_1 PF03029.17 OQS06671.1 - 0.1 12.4 0.1 0.3 10.8 0.0 1.8 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Ion_trans PF00520.31 OQS06672.1 - 1e-20 74.1 16.4 1.3e-20 73.7 16.4 1.1 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 OQS06672.1 - 2.3e-12 46.7 5.9 2.3e-12 46.7 5.9 2.5 2 0 0 2 2 2 1 Ion channel DUF4231 PF14015.6 OQS06672.1 - 0.38 11.3 8.2 1.4 9.5 1.0 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF4231) eIF-1a PF01176.19 OQS06673.1 - 1.1e-11 44.3 0.0 1.8e-11 43.6 0.0 1.4 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 DUF4746 PF15928.5 OQS06673.1 - 0.018 14.5 2.0 0.21 11.0 4.3 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4746) EF-hand_1 PF00036.32 OQS06674.1 - 3.5e-26 88.8 4.7 4.2e-06 25.9 0.0 4.7 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 OQS06674.1 - 2.8e-21 75.8 6.6 2.1e-12 47.3 0.1 2.6 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 OQS06674.1 - 3e-20 70.4 5.4 6.4e-06 25.7 0.2 4.8 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 OQS06674.1 - 9.9e-18 63.7 9.8 9e-10 38.3 0.1 4.5 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.6 OQS06674.1 - 1.3e-13 49.8 3.5 0.00095 18.6 0.0 4.8 4 0 0 4 4 4 3 EF hand EF-hand_9 PF14658.6 OQS06674.1 - 0.04 14.2 0.0 0.12 12.7 0.0 1.8 2 0 0 2 2 2 0 EF-hand domain SPARC_Ca_bdg PF10591.9 OQS06674.1 - 0.25 11.7 2.0 0.38 11.1 0.0 2.3 3 0 0 3 3 3 0 Secreted protein acidic and rich in cysteine Ca binding region CHCH PF06747.13 OQS06675.1 - 1.7e-05 24.8 3.5 2.5e-05 24.3 3.5 1.4 1 0 0 1 1 1 1 CHCH domain DUF1690 PF07956.11 OQS06675.1 - 0.02 15.3 0.5 0.021 15.2 0.5 1.1 1 0 0 1 1 1 0 Protein of Unknown function (DUF1690) Cmc1 PF08583.10 OQS06675.1 - 0.03 14.4 5.8 1.1 9.3 0.8 2.1 1 1 1 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like UPF0203 PF05254.12 OQS06675.1 - 0.033 14.4 4.4 1.7 9.0 4.4 2.3 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0203) COX17 PF05051.13 OQS06675.1 - 0.041 14.2 2.6 0.041 14.2 2.6 1.6 2 0 0 2 2 2 0 Cytochrome C oxidase copper chaperone (COX17) SSI PF00720.17 OQS06675.1 - 0.13 12.2 3.0 0.16 12.0 3.0 1.1 1 0 0 1 1 1 0 Subtilisin inhibitor-like CLPTM1 PF05602.12 OQS06676.1 - 3.7e-112 375.5 0.1 6.9e-112 374.6 0.1 1.4 1 1 0 1 1 1 1 Cleft lip and palate transmembrane protein 1 (CLPTM1) Hpre_diP_synt_I PF07456.11 OQS06676.1 - 1.2 9.1 6.3 0.26 11.3 2.6 1.8 2 0 0 2 2 2 0 Heptaprenyl diphosphate synthase component I Sensor PF13796.6 OQS06677.1 - 0.0027 17.8 0.3 0.0039 17.2 0.3 1.2 1 0 0 1 1 1 1 Putative sensor DUF2207 PF09972.9 OQS06677.1 - 1.9 7.1 4.3 2.3 6.9 4.3 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) GBP PF02263.19 OQS06678.1 - 3.4e-59 200.2 0.0 9.3e-59 198.8 0.0 1.7 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain GBP_C PF02841.14 OQS06678.1 - 1.5e-16 60.7 19.0 1.5e-16 60.7 19.0 2.6 1 1 1 2 2 2 1 Guanylate-binding protein, C-terminal domain MMR_HSR1 PF01926.23 OQS06678.1 - 0.0035 17.4 0.0 0.011 15.8 0.0 1.9 1 0 0 1 1 1 1 50S ribosome-binding GTPase Macoilin PF09726.9 OQS06678.1 - 0.7 8.4 35.3 0.38 9.3 25.0 2.2 1 1 1 2 2 2 0 Macoilin family SHE3 PF17078.5 OQS06678.1 - 1.1 8.9 28.1 0.074 12.8 6.5 2.6 2 0 0 2 2 2 0 SWI5-dependent HO expression protein 3 MatE PF01554.18 OQS06679.1 - 1.6e-50 170.9 31.7 7.1e-26 90.8 7.6 3.1 3 0 0 3 3 3 2 MatE Cation_efflux PF01545.21 OQS06679.1 - 1.7e-27 96.4 1.4 1.7e-27 96.4 1.4 4.2 3 1 0 3 3 3 1 Cation efflux family Thymidylate_kin PF02223.17 OQS06681.1 - 7.5e-48 162.7 0.0 8.7e-48 162.5 0.0 1.0 1 0 0 1 1 1 1 Thymidylate kinase AAA_18 PF13238.6 OQS06681.1 - 1.6e-05 25.4 0.2 0.00014 22.4 0.0 2.0 1 1 1 2 2 2 1 AAA domain dNK PF01712.19 OQS06681.1 - 0.0061 16.4 0.0 0.068 13.0 0.0 2.2 1 1 0 1 1 1 1 Deoxynucleoside kinase SKI PF01202.22 OQS06681.1 - 0.0084 16.2 0.0 2.1 8.5 0.1 2.2 2 0 0 2 2 2 2 Shikimate kinase AAA PF00004.29 OQS06681.1 - 0.014 15.8 0.1 0.22 12.0 0.1 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) KTI12 PF08433.10 OQS06681.1 - 0.021 14.3 0.0 1 8.7 0.0 2.1 2 0 0 2 2 2 0 Chromatin associated protein KTI12 AAA_14 PF13173.6 OQS06681.1 - 0.022 14.8 0.3 0.22 11.5 0.0 2.2 2 1 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 OQS06681.1 - 0.077 13.4 0.1 1.2 9.6 0.0 2.2 2 0 0 2 2 2 0 RNA helicase PI31_Prot_C PF08577.11 OQS06682.1 - 0.00011 23.3 14.1 0.00011 23.3 14.1 2.3 2 0 0 2 2 2 1 PI31 proteasome regulator Endonuclease_7 PF02945.15 OQS06683.1 - 0.046 13.6 1.7 0.069 13.1 0.1 1.8 1 1 1 2 2 2 0 Recombination endonuclease VII MrpF_PhaF PF04066.13 OQS06683.1 - 0.29 11.6 3.4 0.72 10.3 3.4 1.8 1 1 0 1 1 1 0 Multiple resistance and pH regulation protein F (MrpF / PhaF) TMEMspv1-c74-12 PF11044.8 OQS06683.1 - 7.6 6.6 6.7 0.71 9.9 1.9 1.7 2 0 0 2 2 2 0 Plectrovirus spv1-c74 ORF 12 transmembrane protein ThiF PF00899.21 OQS06684.1 - 2.4e-72 243.2 0.1 4.2e-72 242.4 0.1 1.4 1 0 0 1 1 1 1 ThiF family UAE_UbL PF14732.6 OQS06684.1 - 9e-21 74.3 0.1 2.5e-20 72.8 0.1 1.8 1 0 0 1 1 1 1 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain UBA_e1_thiolCys PF10585.9 OQS06684.1 - 9.5e-10 38.8 0.2 6.5e-06 26.3 0.1 2.4 1 1 0 2 2 2 2 Ubiquitin-activating enzyme active site NAD_binding_7 PF13241.6 OQS06684.1 - 9.6e-05 22.8 0.1 0.00023 21.6 0.1 1.6 1 0 0 1 1 1 1 Putative NAD(P)-binding Shikimate_DH PF01488.20 OQS06684.1 - 0.00033 20.7 0.1 0.00072 19.6 0.1 1.6 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Sacchrp_dh_NADP PF03435.18 OQS06684.1 - 0.0023 18.2 1.2 0.012 15.9 1.2 2.1 1 1 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain TrkA_N PF02254.18 OQS06684.1 - 0.06 13.6 0.0 0.14 12.4 0.0 1.7 1 0 0 1 1 1 0 TrkA-N domain Spermine_synth PF01564.17 OQS06684.1 - 0.096 12.1 0.0 0.23 10.8 0.0 1.7 1 0 0 1 1 1 0 Spermine/spermidine synthase domain Pyr_redox PF00070.27 OQS06684.1 - 0.11 13.1 0.1 0.39 11.3 0.1 2.0 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HSF_DNA-bind PF00447.17 OQS06685.1 - 1.4e-27 96.1 0.8 2.4e-27 95.4 0.8 1.4 1 0 0 1 1 1 1 HSF-type DNA-binding Tektin PF03148.14 OQS06685.1 - 0.006 15.4 0.1 0.0095 14.7 0.1 1.2 1 0 0 1 1 1 1 Tektin family RasGAP_C PF03836.15 OQS06685.1 - 0.12 12.5 0.7 0.24 11.5 0.7 1.4 1 0 0 1 1 1 0 RasGAP C-terminus Pkinase_Tyr PF07714.17 OQS06686.1 - 3.7e-27 95.2 0.0 4.5e-27 94.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OQS06686.1 - 1.8e-23 83.3 0.0 2.3e-23 82.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 OQS06686.1 - 0.017 14.5 0.2 0.037 13.4 0.0 1.6 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family DHHC PF01529.20 OQS06688.1 - 1.3e-32 112.7 4.8 1.3e-32 112.7 4.8 2.2 2 0 0 2 2 2 1 DHHC palmitoyltransferase Ank_2 PF12796.7 OQS06688.1 - 3.1e-25 88.6 6.8 9.6e-10 38.9 0.2 3.7 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQS06688.1 - 1.3e-15 57.5 3.0 8.4e-09 35.8 0.2 5.0 2 2 2 5 5 5 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 OQS06688.1 - 3.6e-15 55.8 1.7 3.9e-06 27.0 0.0 4.5 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 OQS06688.1 - 5.4e-15 55.1 13.5 0.0014 19.0 0.4 6.6 7 0 0 7 7 7 3 Ankyrin repeat Ank_3 PF13606.6 OQS06688.1 - 8.9e-09 34.9 2.6 0.038 14.5 0.0 5.5 5 0 0 5 5 5 2 Ankyrin repeat ABC_cobalt PF09819.9 OQS06688.1 - 1.7 8.8 6.1 2.5 8.3 1.7 2.5 2 0 0 2 2 2 0 ABC-type cobalt transport system, permease component DUF4131 PF13567.6 OQS06688.1 - 3.3 7.3 4.8 0.66 9.6 0.6 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) Thioredoxin PF00085.20 OQS06689.1 - 2.4e-25 88.5 0.0 3.2e-25 88.1 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 OQS06689.1 - 2.1e-05 24.9 0.0 0.00058 20.3 0.0 2.2 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_7 PF13899.6 OQS06689.1 - 0.00032 20.8 0.0 0.0008 19.5 0.0 1.7 1 1 0 1 1 1 1 Thioredoxin-like OST3_OST6 PF04756.13 OQS06689.1 - 0.0011 18.4 0.0 0.0019 17.6 0.0 1.3 2 0 0 2 2 2 1 OST3 / OST6 family, transporter family Thioredoxin_8 PF13905.6 OQS06689.1 - 0.0036 17.6 0.0 0.0064 16.8 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like AhpC-TSA PF00578.21 OQS06689.1 - 0.026 14.5 0.0 0.046 13.7 0.0 1.5 1 1 0 1 1 1 0 AhpC/TSA family Thioredoxin_9 PF14595.6 OQS06689.1 - 0.035 13.9 0.0 0.049 13.4 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin Glutaredoxin PF00462.24 OQS06689.1 - 0.14 12.4 0.0 0.24 11.6 0.0 1.4 1 0 0 1 1 1 0 Glutaredoxin NuA4 PF09340.10 OQS06690.1 - 0.0012 18.7 1.1 0.0016 18.3 1.1 1.2 1 0 0 1 1 1 1 Histone acetyltransferase subunit NuA4 Med9 PF07544.13 OQS06690.1 - 0.009 16.1 2.0 0.012 15.7 1.3 1.6 2 0 0 2 2 2 1 RNA polymerase II transcription mediator complex subunit 9 FmiP_Thoc5 PF09766.9 OQS06690.1 - 0.012 14.9 0.2 0.013 14.8 0.2 1.1 1 0 0 1 1 1 0 Fms-interacting protein/Thoc5 DUF1664 PF07889.12 OQS06690.1 - 0.022 14.8 0.1 0.03 14.4 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Cyt-b5 PF00173.28 OQS06692.1 - 3e-12 46.5 0.0 4.6e-12 45.9 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain PRTase_2 PF15609.6 OQS06692.1 - 0.092 12.2 0.1 0.13 11.7 0.1 1.2 1 0 0 1 1 1 0 Phosphoribosyl transferase MWFE PF15879.5 OQS06693.1 - 1.3e-13 50.9 0.3 1.7e-13 50.5 0.3 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase MWFE subunit Glyco_transf_22 PF03901.17 OQS06694.1 - 2.4e-53 181.9 19.6 2.9e-53 181.6 19.6 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family TIR_2 PF13676.6 OQS06695.1 - 1.4e-08 35.4 0.0 0.0061 17.1 0.0 3.1 2 0 0 2 2 2 2 TIR domain NACHT PF05729.12 OQS06695.1 - 2.3e-07 30.9 0.3 8.6e-07 29.0 0.3 2.1 1 0 0 1 1 1 1 NACHT domain SH2 PF00017.24 OQS06695.1 - 2.4e-07 30.8 0.0 7.9e-07 29.1 0.0 1.9 1 0 0 1 1 1 1 SH2 domain ATPase_2 PF01637.18 OQS06695.1 - 3.5e-05 23.8 0.0 0.00014 21.8 0.0 2.0 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea AAA_16 PF13191.6 OQS06695.1 - 4.4e-05 23.9 0.6 0.00031 21.2 0.1 2.4 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 OQS06695.1 - 0.034 14.4 0.0 0.29 11.4 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 OQS06695.1 - 0.037 13.8 0.0 0.095 12.5 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain KAP_NTPase PF07693.14 OQS06695.1 - 0.057 12.7 0.2 9.3 5.4 0.0 2.3 2 0 0 2 2 2 0 KAP family P-loop domain UPF0113_N PF17833.1 OQS06696.1 - 8.9e-27 93.5 0.1 1.5e-26 92.8 0.1 1.4 1 0 0 1 1 1 1 UPF0113 Pre-PUA domain UPF0113 PF03657.13 OQS06696.1 - 8.3e-24 83.6 0.0 1.7e-23 82.7 0.0 1.5 1 0 0 1 1 1 1 UPF0113 PUA domain WYL_3 PF18488.1 OQS06696.1 - 0.12 12.8 0.1 5.8 7.4 0.1 2.4 2 0 0 2 2 2 0 WYL domain Ribosomal_S9 PF00380.19 OQS06697.1 - 4.5e-05 24.0 0.0 0.00018 22.0 0.0 2.1 2 0 0 2 2 2 1 Ribosomal protein S9/S16 Cep57_CLD PF14073.6 OQS06697.1 - 0.023 14.7 13.4 0.06 13.4 13.4 1.7 1 0 0 1 1 1 0 Centrosome localisation domain of Cep57 DUF4724 PF15852.5 OQS06697.1 - 0.028 14.9 0.8 0.19 12.2 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4724) Cauli_AT PF03233.13 OQS06697.1 - 1.6 8.7 4.1 1.3 9.0 1.5 2.1 1 1 0 2 2 2 0 Aphid transmission protein HMGL-like PF00682.19 OQS06698.1 - 1.5e-91 306.6 0.0 3.8e-91 305.3 0.0 1.6 2 0 0 2 2 2 1 HMGL-like LeuA_dimer PF08502.10 OQS06698.1 - 4.6e-34 117.2 1.0 9.2e-34 116.2 1.0 1.5 1 0 0 1 1 1 1 LeuA allosteric (dimerisation) domain Aminotran_1_2 PF00155.21 OQS06699.1 - 4.9e-14 52.3 0.0 1.1e-11 44.6 0.0 2.0 2 0 0 2 2 2 2 Aminotransferase class I and II UPF0172 PF03665.13 OQS06700.1 - 2.7e-39 135.2 0.0 3.1e-39 135.0 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0172) HTH_23 PF13384.6 OQS06701.1 - 0.0048 16.7 0.0 0.0087 15.8 0.0 1.5 1 0 0 1 1 1 1 Homeodomain-like domain DUF1487 PF07368.11 OQS06701.1 - 0.023 14.1 0.2 0.034 13.6 0.2 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1487) HTH_Crp_2 PF13545.6 OQS06701.1 - 0.03 14.3 0.2 0.065 13.2 0.2 1.6 1 1 0 1 1 1 0 Crp-like helix-turn-helix domain DUF4246 PF14033.6 OQS06701.1 - 0.031 13.4 0.7 0.034 13.2 0.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4246) DUF745 PF05335.13 OQS06701.1 - 0.036 13.8 3.5 0.048 13.4 3.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF745) YlqD PF11068.8 OQS06701.1 - 0.042 14.2 3.2 0.065 13.6 2.5 1.7 1 1 1 2 2 2 0 YlqD protein DUF1512 PF07431.12 OQS06701.1 - 0.097 11.7 1.0 0.14 11.1 1.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1512) TMF_DNA_bd PF12329.8 OQS06701.1 - 8.7 6.4 8.1 14 5.7 0.1 3.4 2 1 1 3 3 3 0 TATA element modulatory factor 1 DNA binding Ank_2 PF12796.7 OQS06702.1 - 1.5e-21 76.8 21.9 8.8e-12 45.5 2.2 3.8 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQS06702.1 - 2e-18 66.5 9.2 4.8e-08 33.4 0.2 4.9 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQS06702.1 - 9.1e-16 56.4 14.2 0.0039 17.6 0.0 7.8 6 1 2 8 8 8 5 Ankyrin repeat Ank_5 PF13857.6 OQS06702.1 - 2.4e-15 56.4 11.6 1.6e-07 31.4 0.3 6.5 1 1 4 6 6 6 4 Ankyrin repeats (many copies) Ank PF00023.30 OQS06702.1 - 4.4e-10 39.5 23.4 0.0014 19.0 0.0 6.9 4 3 2 6 6 6 3 Ankyrin repeat ARPC4 PF05856.12 OQS06703.1 - 3.1e-79 264.4 3.3 3.5e-79 264.2 3.3 1.0 1 0 0 1 1 1 1 ARP2/3 complex 20 kDa subunit (ARPC4) RsfS PF02410.15 OQS06704.1 - 4e-22 78.5 0.2 1.6e-21 76.6 0.4 1.8 1 1 1 2 2 2 1 Ribosomal silencing factor during starvation Sporozoite_P67 PF05642.11 OQS06704.1 - 0.19 9.8 1.1 0.28 9.2 1.1 1.3 1 0 0 1 1 1 0 Sporozoite P67 surface antigen CENP-B_dimeris PF09026.10 OQS06704.1 - 7.1 7.1 13.1 0.054 13.9 4.5 2.0 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Pkinase_Tyr PF07714.17 OQS06708.1 - 5.5e-48 163.5 0.0 1e-47 162.6 0.0 1.4 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.25 OQS06708.1 - 1.6e-45 155.6 0.0 2.2e-45 155.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 OQS06708.1 - 0.0025 16.7 0.0 0.0037 16.1 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 OQS06708.1 - 0.023 14.6 0.0 0.081 12.8 0.0 1.7 1 1 0 1 1 1 0 Phosphotransferase enzyme family FNIP PF05725.12 OQS06708.1 - 0.45 10.7 3.3 5.1 7.3 0.2 2.6 2 0 0 2 2 2 0 FNIP Repeat LRR_8 PF13855.6 OQS06708.1 - 0.77 9.6 7.1 5.1 6.9 0.8 3.4 2 1 2 4 4 4 0 Leucine rich repeat LRR_4 PF12799.7 OQS06708.1 - 0.83 10.2 9.0 5 7.7 1.8 3.3 2 1 1 3 3 3 0 Leucine Rich repeats (2 copies) Nuc_sug_transp PF04142.15 OQS06709.1 - 8e-30 104.1 19.4 9.9e-30 103.8 19.4 1.1 1 0 0 1 1 1 1 Nucleotide-sugar transporter UAA PF08449.11 OQS06709.1 - 5.3e-06 25.8 19.5 8.1e-06 25.2 19.5 1.3 1 0 0 1 1 1 1 UAA transporter family TPT PF03151.16 OQS06709.1 - 0.028 13.8 14.9 0.056 12.8 10.6 2.0 2 0 0 2 2 2 0 Triose-phosphate Transporter family EamA PF00892.20 OQS06709.1 - 0.085 13.0 29.9 0.42 10.8 4.5 2.2 2 0 0 2 2 2 0 EamA-like transporter family Cytochrom_C_asm PF01578.20 OQS06709.1 - 0.75 9.5 21.4 0.44 10.3 12.0 3.3 2 2 1 3 3 3 0 Cytochrome C assembly protein Mito_carr PF00153.27 OQS06710.1 - 7.8e-66 218.1 2.8 4.7e-24 84.1 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF3586 PF12131.8 OQS06712.1 - 0.12 12.6 18.1 0.12 12.6 7.5 3.1 1 1 2 3 3 3 0 Protein of unknown function (DUF3586) Mg_trans_NIPA PF05653.14 OQS06713.1 - 6e-18 65.0 7.9 1.4e-17 63.8 7.9 1.5 1 0 0 1 1 1 1 Magnesium transporter NIPA Globin PF00042.22 OQS06713.1 - 4.6e-11 43.3 1.6 0.00015 22.3 0.1 3.0 2 2 0 2 2 2 2 Globin EamA PF00892.20 OQS06713.1 - 0.003 17.7 6.7 0.003 17.7 6.7 3.2 2 1 0 2 2 2 1 EamA-like transporter family FAD_binding_6 PF00970.24 OQS06713.1 - 0.0083 16.5 0.0 0.18 12.2 0.0 2.5 3 0 0 3 3 3 1 Oxidoreductase FAD-binding domain CD34_antigen PF06365.12 OQS06715.1 - 0.00021 21.0 4.2 0.026 14.1 0.1 2.7 3 0 0 3 3 3 2 CD34/Podocalyxin family SRTM1 PF15872.5 OQS06715.1 - 0.0014 18.8 0.4 0.35 11.0 0.1 2.5 2 0 0 2 2 2 2 Serine-rich and transmembrane domain-containing protein 1 DUF4131 PF13567.6 OQS06715.1 - 8.5 6.0 10.3 6 6.5 0.4 3.4 4 0 0 4 4 4 0 Domain of unknown function (DUF4131) UBA PF00627.31 OQS06718.1 - 1.9e-12 46.8 1.2 3.9e-12 45.8 1.2 1.6 1 0 0 1 1 1 1 UBA/TS-N domain Rhomboid PF01694.22 OQS06718.1 - 3.5e-06 27.1 5.0 6.9e-06 26.1 5.0 1.5 1 0 0 1 1 1 1 Rhomboid family DER1 PF04511.15 OQS06718.1 - 3.7e-05 23.8 1.7 6.5e-05 23.0 1.7 1.4 1 1 0 1 1 1 1 Der1-like family CUE PF02845.16 OQS06718.1 - 0.0029 17.3 0.6 0.0055 16.4 0.0 1.8 2 0 0 2 2 2 1 CUE domain UBA_4 PF14555.6 OQS06718.1 - 0.023 14.5 1.0 0.023 14.5 1.0 1.7 2 0 0 2 2 2 0 UBA-like domain DUF1751 PF08551.10 OQS06718.1 - 0.026 15.1 0.2 0.067 13.8 0.2 1.8 1 0 0 1 1 1 0 Eukaryotic integral membrane protein (DUF1751) UBA_3 PF09288.10 OQS06718.1 - 0.045 13.6 0.0 0.085 12.7 0.0 1.4 1 0 0 1 1 1 0 Fungal ubiquitin-associated domain Myosin_head PF00063.21 OQS06719.1 - 1.6e-103 347.3 0.1 2.2e-103 346.8 0.1 1.2 1 0 0 1 1 1 1 Myosin head (motor domain) Ank_2 PF12796.7 OQS06719.1 - 9.1e-17 61.4 0.9 9.3e-10 39.0 0.3 4.3 3 0 0 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQS06719.1 - 8e-16 58.2 6.3 1.6e-08 34.9 0.2 4.8 6 0 0 6 6 6 2 Ankyrin repeats (many copies) Aida_C2 PF14186.6 OQS06719.1 - 1.6e-15 57.0 0.0 5.3e-15 55.3 0.0 1.8 1 1 0 1 1 1 1 Cytoskeletal adhesion Ank_3 PF13606.6 OQS06719.1 - 8.7e-14 50.3 1.4 0.0004 20.6 0.0 6.1 5 0 0 5 5 5 2 Ankyrin repeat IQ PF00612.27 OQS06719.1 - 2.4e-11 42.4 65.2 0.0037 16.9 0.7 11.8 11 0 0 11 11 11 6 IQ calmodulin-binding motif Ank_5 PF13857.6 OQS06719.1 - 9.2e-11 41.8 1.6 0.086 13.2 0.0 4.7 3 1 1 4 4 4 3 Ankyrin repeats (many copies) PH PF00169.29 OQS06719.1 - 9.2e-11 42.2 0.1 4e-10 40.1 0.1 2.2 2 0 0 2 2 2 1 PH domain Ank PF00023.30 OQS06719.1 - 1.7e-10 40.8 3.4 0.091 13.3 0.0 5.7 4 1 0 4 4 4 3 Ankyrin repeat Vps16_N PF04841.13 OQS06719.1 - 0.062 12.1 0.0 0.29 9.9 0.0 1.9 2 0 0 2 2 2 0 Vps16, N-terminal region zf-RING_2 PF13639.6 OQS06720.1 - 3.6e-10 40.0 4.5 3.6e-10 40.0 4.5 3.8 4 1 0 4 4 4 2 Ring finger domain zf-RING_11 PF17123.5 OQS06720.1 - 1e-09 38.0 2.8 1e-09 38.0 2.8 3.0 4 1 0 4 4 4 1 RING-like zinc finger zf-RING_UBOX PF13445.6 OQS06720.1 - 2.8e-08 33.6 0.7 2.8e-08 33.6 0.7 4.9 3 1 1 4 4 4 1 RING-type zinc-finger zf-C3HC4 PF00097.25 OQS06720.1 - 1.1e-07 31.6 4.7 1.1e-07 31.6 4.7 5.0 3 1 1 4 4 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 OQS06720.1 - 7.5e-07 28.9 4.8 7.5e-07 28.9 4.8 4.9 4 3 1 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OQS06720.1 - 2.1e-05 24.4 5.0 2.1e-05 24.4 5.0 4.4 3 1 0 3 3 3 1 zinc-RING finger domain zf-rbx1 PF12678.7 OQS06720.1 - 6e-05 23.2 7.3 6e-05 23.2 7.3 4.3 3 2 2 5 5 3 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 OQS06720.1 - 0.0001 22.3 2.5 0.0001 22.3 2.5 3.1 3 1 0 3 3 3 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.6 OQS06720.1 - 0.00014 21.7 2.7 0.00014 21.7 2.7 4.5 4 2 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 OQS06720.1 - 0.00014 21.5 3.3 0.00014 21.5 3.3 4.1 3 2 0 3 3 2 1 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.6 OQS06720.1 - 0.0013 18.8 3.8 0.0013 18.8 3.8 4.9 4 2 0 4 4 3 1 zinc finger of C3HC4-type, RING Prok-RING_1 PF14446.6 OQS06720.1 - 0.013 15.4 0.3 0.013 15.4 0.3 5.2 4 1 1 5 5 5 0 Prokaryotic RING finger family 1 PHD PF00628.29 OQS06720.1 - 0.02 14.8 2.2 0.02 14.8 2.2 4.3 3 2 0 3 3 3 0 PHD-finger Zn_ribbon_17 PF17120.5 OQS06720.1 - 0.032 13.9 2.0 0.032 13.9 2.0 3.4 3 1 0 3 3 3 0 Zinc-ribbon, C4HC2 type zinc-ribbons_6 PF07191.12 OQS06720.1 - 6.8 6.7 23.0 5.2 7.1 0.0 4.2 2 1 1 3 3 3 0 zinc-ribbons FPN1 PF06963.12 OQS06722.1 - 1.3e-87 294.2 29.4 4.2e-85 285.9 29.4 2.1 1 1 0 1 1 1 1 Ferroportin1 (FPN1) Peptidase_C1 PF00112.23 OQS06723.1 - 4.7e-45 154.3 3.7 6e-45 154.0 3.7 1.1 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.15 OQS06723.1 - 0.17 10.7 0.9 0.22 10.3 0.1 1.5 2 0 0 2 2 2 0 Peptidase C1-like family Prefoldin_2 PF01920.20 OQS06724.1 - 1.7e-20 73.0 15.9 2.2e-20 72.6 15.9 1.2 1 0 0 1 1 1 1 Prefoldin subunit Rh5 PF18515.1 OQS06724.1 - 0.00096 18.5 3.6 0.0011 18.3 3.6 1.1 1 0 0 1 1 1 1 Rh5 coiled-coil domain DUF3585 PF12130.8 OQS06724.1 - 0.11 12.6 13.5 0.47 10.6 4.5 2.1 2 0 0 2 2 2 0 Bivalent Mical/EHBP Rab binding domain Prefoldin_3 PF13758.6 OQS06724.1 - 0.38 10.9 9.3 0.12 12.4 5.8 2.0 2 1 0 2 2 2 0 Prefoldin subunit Prefoldin PF02996.17 OQS06724.1 - 0.53 10.2 13.6 6.6 6.7 13.6 2.2 1 1 0 1 1 1 0 Prefoldin subunit DUF1664 PF07889.12 OQS06724.1 - 2 8.4 11.6 0.47 10.5 5.2 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Ribosomal_60s PF00428.19 OQS06724.1 - 2.4 8.8 10.8 0.12 13.0 5.4 1.6 2 0 0 2 2 2 0 60s Acidic ribosomal protein COG2 PF06148.11 OQS06724.1 - 2.9 8.0 10.8 0.33 11.0 5.1 1.9 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 AAA_23 PF13476.6 OQS06724.1 - 4.7 7.6 9.8 6.4 7.2 9.8 1.2 1 0 0 1 1 1 0 AAA domain APG6_N PF17675.1 OQS06724.1 - 6.6 7.3 19.3 1.7 9.2 10.9 2.0 1 1 1 2 2 2 0 Apg6 coiled-coil region FlaC_arch PF05377.11 OQS06724.1 - 7.5 7.0 12.7 11 6.5 4.9 2.6 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) Gaa1 PF04114.14 OQS06725.1 - 1.1e-73 249.1 12.6 4.7e-70 237.0 1.4 2.3 2 0 0 2 2 2 2 Gaa1-like, GPI transamidase component Pkinase PF00069.25 OQS06725.1 - 2.9e-23 82.6 0.0 4.4e-23 82.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQS06725.1 - 3.5e-20 72.4 0.0 5e-20 71.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OQS06725.1 - 0.0017 17.7 0.0 0.0029 17.0 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 OQS06725.1 - 0.061 12.7 0.0 0.12 11.8 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 OQS06727.1 - 1.6e-40 139.2 0.0 2.5e-40 138.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQS06727.1 - 8.5e-39 133.4 0.0 1.3e-38 132.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OQS06727.1 - 0.046 12.5 0.0 0.078 11.7 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase LRR_4 PF12799.7 OQS06727.1 - 0.096 13.1 0.1 0.37 11.3 0.1 2.0 1 0 0 1 1 1 0 Leucine Rich repeats (2 copies) APH PF01636.23 OQS06727.1 - 0.097 12.6 0.0 0.19 11.6 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family DUF4690 PF15756.5 OQS06727.1 - 0.15 12.7 0.2 0.38 11.4 0.2 1.6 1 0 0 1 1 1 0 Small Novel Rich in Cartilage FYVE PF01363.21 OQS06730.1 - 1.1e-07 31.9 73.8 6.4e-07 29.4 9.1 5.3 5 0 0 5 5 5 3 FYVE zinc finger FYVE_2 PF02318.16 OQS06730.1 - 1.4e-07 31.7 46.8 0.0006 20.0 3.2 4.9 4 0 0 4 4 4 3 FYVE-type zinc finger IBR PF01485.21 OQS06730.1 - 1.6e-05 25.0 44.3 0.023 14.9 5.1 5.0 4 0 0 4 4 4 4 IBR domain, a half RING-finger domain Strumpellin PF10266.9 OQS06730.1 - 0.014 13.2 0.0 0.26 8.9 0.0 2.0 2 0 0 2 2 2 0 Hereditary spastic paraplegia protein strumpellin DUF3074 PF11274.8 OQS06730.1 - 0.073 13.1 0.0 81 3.1 0.0 4.5 5 0 0 5 5 5 0 Protein of unknown function (DUF3074) Cytochrome_CBB3 PF13442.6 OQS06730.1 - 0.11 12.8 1.0 40 4.6 0.0 4.0 4 0 0 4 4 4 0 Cytochrome C oxidase, cbb3-type, subunit III MbtH PF03621.13 OQS06730.1 - 0.14 11.6 0.9 1e+02 2.4 0.0 4.2 4 0 0 4 4 4 0 MbtH-like protein START PF01852.19 OQS06731.1 - 1.2e-05 24.9 1.1 6.8e-05 22.4 0.0 2.2 2 0 0 2 2 2 1 START domain FYVE PF01363.21 OQS06731.1 - 7.4e-05 22.8 14.4 0.00017 21.6 14.4 1.6 1 1 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.16 OQS06731.1 - 0.0051 17.0 8.4 0.01 16.0 8.4 1.5 1 0 0 1 1 1 1 FYVE-type zinc finger Sep15_SelM PF08806.11 OQS06731.1 - 0.12 12.6 0.0 1.3 9.2 0.0 2.7 2 0 0 2 2 2 0 Sep15/SelM redox domain IBR PF01485.21 OQS06731.1 - 5 7.4 12.1 0.51 10.6 5.9 2.3 2 0 0 2 2 2 0 IBR domain, a half RING-finger domain SDF PF00375.18 OQS06732.1 - 1.6e-70 238.1 44.9 9.1e-70 235.6 44.9 1.8 1 1 0 1 1 1 1 Sodium:dicarboxylate symporter family Ras PF00071.22 OQS06732.1 - 0.041 13.5 0.2 0.073 12.7 0.2 1.3 1 0 0 1 1 1 0 Ras family FYVE PF01363.21 OQS06733.1 - 0.81 9.9 24.2 0.072 13.2 19.4 1.7 2 0 0 2 2 2 0 FYVE zinc finger MatE PF01554.18 OQS06734.1 - 4e-36 124.1 19.5 4e-23 81.9 6.8 2.8 4 0 0 4 4 4 2 MatE Polysacc_synt PF01943.17 OQS06734.1 - 0.00078 18.9 14.1 0.0015 18.0 1.2 2.3 2 0 0 2 2 2 2 Polysaccharide biosynthesis protein Polysacc_synt_C PF14667.6 OQS06734.1 - 0.018 15.1 34.2 0.09 12.8 16.7 3.4 3 1 0 3 3 3 0 Polysaccharide biosynthesis C-terminal domain RCC1 PF00415.18 OQS06735.1 - 4e-47 158.6 32.6 4.3e-11 43.2 0.0 9.3 8 2 0 8 8 8 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 OQS06735.1 - 1.1e-31 108.0 32.0 6.9e-12 44.8 0.6 7.5 8 0 0 8 8 8 5 Regulator of chromosome condensation (RCC1) repeat Ank_2 PF12796.7 OQS06735.1 - 2.5e-12 47.2 0.0 5.7e-12 46.1 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQS06735.1 - 1.8e-11 44.3 0.3 1e-05 26.0 0.0 3.2 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 OQS06735.1 - 3.4e-11 43.1 1.3 3.2e-06 27.3 0.0 3.8 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.6 OQS06735.1 - 2.9e-10 39.5 0.5 3e-05 24.1 0.0 3.8 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 OQS06735.1 - 6.9e-09 35.8 1.1 1.7e-05 25.0 0.1 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Radial_spoke_3 PF06098.11 OQS06737.1 - 2e-52 178.3 2.8 2.6e-52 177.9 2.8 1.1 1 0 0 1 1 1 1 Radial spoke protein 3 2OG-FeII_Oxy_2 PF13532.6 OQS06738.1 - 1.3e-19 71.2 0.8 3e-19 70.0 0.0 1.9 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily Methyltransf_11 PF08241.12 OQS06738.1 - 1.5e-09 38.3 0.0 4.4e-09 36.9 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OQS06738.1 - 2.8e-07 31.2 0.1 7.1e-07 29.8 0.1 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.15 OQS06738.1 - 4.1e-06 26.8 0.0 8.9e-06 25.7 0.0 1.5 1 0 0 1 1 1 1 Hypothetical methyltransferase Rhodanese PF00581.20 OQS06738.1 - 4.3e-05 24.0 0.0 0.00015 22.3 0.0 1.9 1 1 0 1 1 1 1 Rhodanese-like domain Methyltransf_23 PF13489.6 OQS06738.1 - 0.0011 18.8 0.0 0.0079 16.0 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 OQS06738.1 - 0.0018 18.1 0.0 0.0082 16.0 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 OQS06738.1 - 0.005 16.2 0.0 0.012 14.9 0.0 1.6 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 OQS06738.1 - 0.0066 17.2 0.6 0.026 15.2 0.2 2.3 2 1 0 2 2 2 1 Methyltransferase domain TauE PF01925.19 OQS06739.1 - 6.5e-25 88.1 33.2 3e-14 53.2 0.8 2.5 2 1 0 2 2 2 2 Sulfite exporter TauE/SafE DUF2970 PF11174.8 OQS06739.1 - 0.05 13.5 1.1 0.25 11.2 0.1 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2970) IPPT PF01715.17 OQS06740.1 - 3.5e-72 242.9 0.0 4.8e-72 242.5 0.0 1.1 1 0 0 1 1 1 1 IPP transferase IPT PF01745.16 OQS06740.1 - 5.8e-07 29.2 0.0 1.1e-06 28.2 0.0 1.5 1 0 0 1 1 1 1 Isopentenyl transferase zf-C2H2_jaz PF12171.8 OQS06740.1 - 6.5e-07 29.5 0.0 6.5e-07 29.5 0.0 1.7 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding DUF3449 PF11931.8 OQS06740.1 - 3.3e-05 23.7 0.3 7.7e-05 22.6 0.3 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3449) AAA_18 PF13238.6 OQS06740.1 - 7.1e-05 23.4 0.2 0.082 13.5 0.0 2.6 1 1 0 2 2 2 2 AAA domain AAA_33 PF13671.6 OQS06740.1 - 0.00017 21.8 0.1 0.0031 17.7 0.1 2.3 1 1 0 1 1 1 1 AAA domain zf-met PF12874.7 OQS06740.1 - 0.001 19.3 0.1 0.001 19.3 0.1 1.8 2 0 0 2 2 2 1 Zinc-finger of C2H2 type Fibritin_C PF07921.12 OQS06740.1 - 0.007 16.5 0.2 0.057 13.5 0.1 2.3 2 0 0 2 2 2 1 Fibritin C-terminal region AAA_28 PF13521.6 OQS06740.1 - 0.095 12.9 0.2 0.28 11.4 0.0 1.9 2 0 0 2 2 2 0 AAA domain CbiA PF01656.23 OQS06740.1 - 1.2 9.2 2.9 3.2 7.8 2.9 2.1 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_26 PF13500.6 OQS06741.1 - 1.9e-37 129.0 0.0 1.1e-36 126.6 0.0 2.1 2 0 0 2 2 2 1 AAA domain Homoserine_dh PF00742.19 OQS06741.1 - 6.5e-29 101.1 0.1 1.6e-28 99.8 0.1 1.7 1 0 0 1 1 1 1 Homoserine dehydrogenase SET PF00856.28 OQS06741.1 - 2.7e-12 47.4 0.0 6.2e-12 46.2 0.0 1.7 1 0 0 1 1 1 1 SET domain CbiA PF01656.23 OQS06741.1 - 1.7e-09 37.8 0.0 7.3e-09 35.8 0.0 2.1 2 0 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain DRTGG PF07085.12 OQS06741.1 - 0.0018 18.1 0.0 0.004 16.9 0.0 1.6 1 0 0 1 1 1 1 DRTGG domain DUF1611 PF07755.11 OQS06741.1 - 0.026 13.8 0.6 0.13 11.5 0.1 2.3 3 0 0 3 3 3 0 Domain of unknown function (DUF1611_C) P-loop domain NAD_binding_3 PF03447.16 OQS06741.1 - 0.14 12.8 0.0 0.33 11.6 0.0 1.7 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain ER_lumen_recept PF00810.18 OQS06742.1 - 2.3e-51 174.5 8.3 2.3e-51 174.5 8.3 1.5 2 0 0 2 2 2 1 ER lumen protein retaining receptor PQ-loop PF04193.14 OQS06742.1 - 0.02 14.6 0.1 0.02 14.6 0.1 3.8 4 1 1 5 5 5 0 PQ loop repeat Apq12 PF12716.7 OQS06742.1 - 8.3 6.5 9.8 0.18 11.8 0.7 2.7 3 0 0 3 3 3 0 Nuclear pore assembly and biogenesis LRR_8 PF13855.6 OQS06743.1 - 1.1e-19 69.9 39.6 1.4e-07 31.2 2.1 6.5 5 2 6 11 11 11 5 Leucine rich repeat LRR_9 PF14580.6 OQS06743.1 - 4.9e-19 68.5 3.2 4.5e-15 55.6 0.1 2.5 2 0 0 2 2 2 2 Leucine-rich repeat LRR_4 PF12799.7 OQS06743.1 - 3e-09 37.0 24.7 0.015 15.7 6.2 7.2 5 2 2 7 7 7 4 Leucine Rich repeats (2 copies) Notch PF00066.17 OQS06743.1 - 0.003 18.0 11.7 0.0067 16.9 11.7 1.6 1 0 0 1 1 1 1 LNR domain DUF3557 PF12078.8 OQS06743.1 - 0.028 14.4 4.0 0.062 13.2 1.4 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF3557) Arf PF00025.21 OQS06744.1 - 6.5e-85 283.0 0.1 6.5e-57 191.8 0.0 2.1 1 1 1 2 2 2 2 ADP-ribosylation factor family Roc PF08477.13 OQS06744.1 - 2.7e-23 82.4 0.6 1.8e-12 47.5 0.1 2.2 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 OQS06744.1 - 7.1e-20 71.2 1.2 2.4e-10 40.2 0.1 2.2 2 0 0 2 2 2 2 Ras family SRPRB PF09439.10 OQS06744.1 - 3e-19 69.1 0.0 9.5e-13 48.0 0.0 2.1 2 0 0 2 2 2 2 Signal recognition particle receptor beta subunit G-alpha PF00503.20 OQS06744.1 - 9.6e-14 51.3 8.2 2.1e-06 27.2 0.1 4.3 2 2 2 4 4 4 2 G-protein alpha subunit Gtr1_RagA PF04670.12 OQS06744.1 - 1.5e-12 47.4 0.7 1.1e-05 25.0 0.1 2.5 2 1 0 2 2 2 2 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 OQS06744.1 - 3.1e-12 46.6 0.0 1.3e-05 25.3 0.0 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 OQS06744.1 - 2.7e-07 30.6 0.3 0.2 11.5 0.0 3.3 3 1 0 3 3 3 2 RsgA GTPase FeoB_N PF02421.18 OQS06744.1 - 4.4e-05 23.1 0.3 0.26 10.8 0.0 3.3 3 1 0 3 3 3 1 Ferrous iron transport protein B AAA_14 PF13173.6 OQS06744.1 - 0.00021 21.3 0.0 0.69 9.9 0.0 3.3 2 1 0 3 3 3 1 AAA domain ABC_tran PF00005.27 OQS06744.1 - 0.0003 21.3 0.0 0.0025 18.3 0.0 2.1 2 0 0 2 2 2 1 ABC transporter cobW PF02492.19 OQS06744.1 - 0.00057 19.5 1.8 0.32 10.6 0.0 3.1 4 0 0 4 4 4 2 CobW/HypB/UreG, nucleotide-binding domain MeaB PF03308.16 OQS06744.1 - 0.0029 16.6 0.1 1.1 8.1 0.0 2.3 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_24 PF13479.6 OQS06744.1 - 0.0043 16.8 2.4 0.075 12.7 0.4 2.5 2 1 0 2 2 2 1 AAA domain AAA_22 PF13401.6 OQS06744.1 - 0.0053 17.0 0.5 0.082 13.2 0.1 2.8 2 2 0 2 2 2 1 AAA domain NACHT PF05729.12 OQS06744.1 - 0.0059 16.5 0.5 1.4 8.8 0.2 3.1 2 1 0 2 2 2 1 NACHT domain MobB PF03205.14 OQS06744.1 - 0.0061 16.4 0.0 0.15 11.9 0.0 2.3 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_33 PF13671.6 OQS06744.1 - 0.011 15.9 0.0 0.54 10.4 0.0 2.5 2 0 0 2 2 2 0 AAA domain TniB PF05621.11 OQS06744.1 - 0.011 15.1 0.0 1.3 8.4 0.0 2.3 2 0 0 2 2 2 0 Bacterial TniB protein ATP_bind_1 PF03029.17 OQS06744.1 - 0.019 14.8 4.4 0.48 10.2 0.5 3.3 3 1 1 4 4 4 0 Conserved hypothetical ATP binding protein AAA_16 PF13191.6 OQS06744.1 - 0.041 14.3 0.0 0.34 11.3 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain AAA_29 PF13555.6 OQS06744.1 - 0.05 13.3 0.0 1.1 9.0 0.0 3.0 3 0 0 3 3 3 0 P-loop containing region of AAA domain Dynamin_N PF00350.23 OQS06744.1 - 0.063 13.3 0.1 28 4.7 0.0 3.6 4 0 0 4 4 4 0 Dynamin family ATPase_2 PF01637.18 OQS06744.1 - 0.14 12.1 0.0 2.1 8.2 0.0 2.4 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea AAA_23 PF13476.6 OQS06744.1 - 0.17 12.4 0.1 0.5 10.8 0.0 1.8 2 0 0 2 2 2 0 AAA domain NOG1 PF06858.14 OQS06744.1 - 0.2 11.4 4.0 2.3 8.1 0.2 2.8 2 1 0 2 2 2 0 Nucleolar GTP-binding protein 1 (NOG1) ATPase PF06745.13 OQS06744.1 - 0.23 10.8 0.3 8.2 5.7 0.0 2.9 4 0 0 4 4 4 0 KaiC SCO1-SenC PF02630.14 OQS06745.1 - 3e-38 130.8 0.1 5.6e-38 129.9 0.1 1.5 1 0 0 1 1 1 1 SCO1/SenC Pkinase_Tyr PF07714.17 OQS06745.1 - 5.5e-25 88.1 0.0 1e-24 87.3 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OQS06745.1 - 4.1e-24 85.4 0.0 6.7e-24 84.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain AhpC-TSA PF00578.21 OQS06745.1 - 3.4e-05 23.7 0.0 6.7e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_8 PF13905.6 OQS06745.1 - 0.051 13.9 0.0 0.14 12.5 0.0 1.8 1 0 0 1 1 1 0 Thioredoxin-like DUF5605 PF18310.1 OQS06745.1 - 0.12 12.3 0.2 2.1 8.3 0.0 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF5605) Pkinase_fungal PF17667.1 OQS06745.1 - 0.18 10.5 0.0 0.27 10.0 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase PIG-F PF06699.11 OQS06745.1 - 0.94 9.6 8.8 0.068 13.3 1.7 2.1 1 1 1 2 2 2 0 GPI biosynthesis protein family Pig-F Ras PF00071.22 OQS06746.1 - 1.3e-32 112.6 0.0 1.6e-32 112.3 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OQS06746.1 - 3.2e-14 53.2 0.0 4.8e-14 52.6 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OQS06746.1 - 1.3e-06 28.0 0.0 1.7e-06 27.6 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family PduV-EutP PF10662.9 OQS06746.1 - 0.00054 19.7 0.0 0.073 12.8 0.0 2.2 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation Gtr1_RagA PF04670.12 OQS06746.1 - 0.00063 19.2 0.0 0.00076 18.9 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 OQS06746.1 - 0.0024 17.9 0.0 0.0039 17.2 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase ATP_bind_1 PF03029.17 OQS06746.1 - 0.0039 17.0 0.2 1.1 9.0 0.0 2.1 1 1 1 2 2 2 2 Conserved hypothetical ATP binding protein cobW PF02492.19 OQS06746.1 - 0.0047 16.5 0.2 1.5 8.3 0.2 2.1 1 1 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain AAA_22 PF13401.6 OQS06746.1 - 0.0066 16.7 0.0 0.012 15.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain NACHT PF05729.12 OQS06746.1 - 0.0087 16.0 0.0 0.017 15.1 0.0 1.4 1 0 0 1 1 1 1 NACHT domain SRPRB PF09439.10 OQS06746.1 - 0.0099 15.3 0.0 0.013 15.0 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_16 PF13191.6 OQS06746.1 - 0.012 16.0 0.0 0.019 15.3 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain RsgA_GTPase PF03193.16 OQS06746.1 - 0.03 14.2 0.1 0.16 11.9 0.0 2.0 2 0 0 2 2 2 0 RsgA GTPase Septin PF00735.18 OQS06746.1 - 0.062 12.6 0.0 0.092 12.0 0.0 1.2 1 0 0 1 1 1 0 Septin AAA_7 PF12775.7 OQS06746.1 - 0.13 11.8 0.1 0.2 11.1 0.1 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_30 PF13604.6 OQS06746.1 - 0.2 11.3 0.0 0.29 10.8 0.0 1.2 1 0 0 1 1 1 0 AAA domain ubiquitin PF00240.23 OQS06747.1 - 1.1e-22 79.6 0.8 8.9e-16 57.4 0.2 2.0 2 0 0 2 2 2 2 Ubiquitin family Rad60-SLD PF11976.8 OQS06747.1 - 5.6e-10 38.9 1.8 6.7e-08 32.2 0.4 2.0 2 0 0 2 2 2 2 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 OQS06747.1 - 2.1e-06 28.1 0.1 3.5e-06 27.4 0.1 1.4 1 1 0 1 1 1 1 Ubiquitin-like domain Ubiquitin_5 PF18037.1 OQS06747.1 - 0.022 15.1 0.1 0.22 11.9 0.1 2.0 2 0 0 2 2 2 0 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 OQS06747.1 - 0.15 12.2 0.1 0.63 10.2 0.1 2.2 1 1 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Fer4 PF00037.27 OQS06748.1 - 3.6e-14 51.9 17.5 1.5e-08 34.1 4.5 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.7 OQS06748.1 - 8.8e-13 48.6 10.5 1.5e-12 47.9 10.5 1.4 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_16 PF13484.6 OQS06748.1 - 4.6e-11 43.5 5.8 4.2e-05 24.4 0.1 2.3 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_21 PF14697.6 OQS06748.1 - 4.2e-10 39.6 3.5 0.00016 21.7 0.4 2.1 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_9 PF13187.6 OQS06748.1 - 1.4e-08 34.8 10.3 2.1e-08 34.2 10.3 1.3 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_10 PF13237.6 OQS06748.1 - 2.3e-08 34.0 21.9 4.7e-06 26.6 12.8 2.0 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_6 PF12837.7 OQS06748.1 - 2.7e-07 30.4 17.8 0.00033 20.6 5.4 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_8 PF13183.6 OQS06748.1 - 9e-07 29.3 20.0 0.00025 21.4 11.9 2.1 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_2 PF12797.7 OQS06748.1 - 1e-06 28.4 12.1 0.0023 17.9 2.0 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_4 PF12800.7 OQS06748.1 - 6.2e-06 26.3 11.4 0.00029 21.1 2.0 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_17 PF13534.6 OQS06748.1 - 0.00028 21.4 11.2 0.031 14.8 12.5 2.3 1 1 2 3 3 3 3 4Fe-4S dicluster domain c-SKI_SMAD_bind PF08782.10 OQS06748.1 - 0.0064 16.7 5.7 0.61 10.4 0.5 2.3 1 1 1 2 2 2 2 c-SKI Smad4 binding domain Fer4_13 PF13370.6 OQS06748.1 - 0.01 16.4 14.7 0.59 10.7 2.7 2.6 2 0 0 2 2 2 0 4Fe-4S single cluster domain of Ferredoxin I Fer4_18 PF13746.6 OQS06748.1 - 0.035 14.3 8.7 0.91 9.7 1.5 2.2 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_3 PF12798.7 OQS06748.1 - 0.15 13.0 16.3 0.29 12.2 4.1 2.2 2 0 0 2 2 2 0 4Fe-4S binding domain ETF_QO PF05187.13 OQS06748.1 - 0.24 11.6 5.8 1.1 9.4 0.6 2.2 1 1 1 2 2 2 0 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S Fer4_22 PF17179.4 OQS06748.1 - 0.78 10.6 11.9 2.4 9.1 1.9 2.2 1 1 1 2 2 2 0 4Fe-4S dicluster domain Ephrin_rec_like PF07699.13 OQS06749.1 - 5.7e-05 22.8 373.9 0.011 15.4 3.0 33.9 6 6 32 39 39 39 33 Putative ephrin-receptor like Fcf2 PF08698.11 OQS06750.1 - 4.4e-31 107.2 1.2 4.4e-31 107.2 1.2 3.1 3 0 0 3 3 3 1 Fcf2 pre-rRNA processing Ank_2 PF12796.7 OQS06750.1 - 2.5e-30 104.9 28.3 1.6e-06 28.6 0.3 7.6 2 1 5 8 8 8 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQS06750.1 - 1.6e-19 70.0 24.9 0.0018 18.8 0.5 9.1 3 2 6 9 9 9 9 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQS06750.1 - 1.6e-14 52.6 14.2 2.9 8.7 0.0 10.9 11 0 0 11 11 11 4 Ankyrin repeat Ank_5 PF13857.6 OQS06750.1 - 2.9e-11 43.4 25.7 0.6 10.5 0.0 12.1 5 3 7 12 12 12 4 Ankyrin repeats (many copies) rRNA_processing PF08524.11 OQS06750.1 - 6e-09 36.1 24.5 6e-09 36.1 24.5 4.8 3 2 2 5 5 5 1 rRNA processing Ank PF00023.30 OQS06750.1 - 0.0022 18.4 21.4 37 5.0 0.1 10.1 4 3 2 7 7 7 0 Ankyrin repeat Transmemb_17 PF09799.9 OQS06751.1 - 1.6e-20 73.7 10.5 2e-20 73.4 10.5 1.1 1 0 0 1 1 1 1 Predicted membrane protein Skp1_POZ PF03931.15 OQS06752.1 - 6.8e-13 48.6 0.0 9.6e-13 48.1 0.0 1.2 1 0 0 1 1 1 1 Skp1 family, tetramerisation domain BTB PF00651.31 OQS06752.1 - 1e-05 25.7 0.1 1.4e-05 25.3 0.1 1.3 1 1 0 1 1 1 1 BTB/POZ domain Phage_int_SAM_5 PF13102.6 OQS06752.1 - 0.071 13.5 0.0 0.12 12.8 0.0 1.3 1 1 0 1 1 1 0 Phage integrase SAM-like domain DcpS_C PF11969.8 OQS06753.1 - 8e-28 97.2 1.0 2.6e-27 95.6 0.1 2.1 2 0 0 2 2 2 1 Scavenger mRNA decapping enzyme C-term binding DcpS PF05652.12 OQS06753.1 - 6.6e-13 49.4 0.0 1.2e-12 48.5 0.0 1.5 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme (DcpS) N-terminal NMT1 PF09084.11 OQS06753.1 - 0.068 13.1 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 NMT1/THI5 like CinA PF02464.17 OQS06754.1 - 5.7e-08 32.5 0.4 9.8e-08 31.7 0.4 1.4 1 0 0 1 1 1 1 Competence-damaged protein CTP_transf_like PF01467.26 OQS06754.1 - 0.00021 21.5 0.0 0.001 19.3 0.0 2.1 1 1 0 1 1 1 1 Cytidylyltransferase-like Porin_3 PF01459.22 OQS06755.1 - 5.6e-38 130.9 7.8 6.3e-38 130.8 7.8 1.0 1 0 0 1 1 1 1 Eukaryotic porin Exo_endo_phos PF03372.23 OQS06757.1 - 4.4e-45 154.0 0.0 1.7e-44 152.1 0.0 1.9 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family fn3 PF00041.21 OQS06757.1 - 4.9e-07 30.0 0.1 1.1e-06 28.8 0.1 1.6 1 0 0 1 1 1 1 Fibronectin type III domain Pur_ac_phosph_N PF16656.5 OQS06757.1 - 0.0035 17.9 0.0 0.0088 16.6 0.0 1.6 1 0 0 1 1 1 1 Purple acid Phosphatase, N-terminal domain PP-binding PF00550.25 OQS06758.1 - 2e-10 40.9 0.2 2.6e-10 40.5 0.2 1.2 1 0 0 1 1 1 1 Phosphopantetheine attachment site PP-binding_2 PF14573.6 OQS06758.1 - 0.0014 18.8 1.2 0.002 18.3 1.2 1.3 1 1 0 1 1 1 1 Acyl-carrier His_Phos_2 PF00328.22 OQS06759.1 - 2.8e-15 56.5 0.0 3.8e-14 52.9 0.0 3.6 2 2 1 3 3 3 2 Histidine phosphatase superfamily (branch 2) Dimer_Tnp_hAT PF05699.14 OQS06760.1 - 2.8e-09 36.6 0.6 7.2e-09 35.3 0.6 1.7 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region zf-BED PF02892.15 OQS06760.1 - 0.00068 19.6 5.8 1.4 9.0 0.1 3.7 3 0 0 3 3 3 2 BED zinc finger zf-UDP PF14569.6 OQS06760.1 - 0.022 14.9 1.8 1 9.5 0.2 2.8 2 0 0 2 2 2 0 Zinc-binding RING-finger Elf1 PF05129.13 OQS06760.1 - 0.77 9.8 4.1 20 5.3 0.2 3.9 4 0 0 4 4 4 0 Transcription elongation factor Elf1 like TPR_12 PF13424.6 OQS06761.1 - 1.7e-13 50.6 6.8 7.6e-11 42.1 1.4 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat SH2 PF00017.24 OQS06761.1 - 1.8e-11 43.9 0.0 4e-11 42.8 0.0 1.6 1 0 0 1 1 1 1 SH2 domain TPR_10 PF13374.6 OQS06761.1 - 3.5e-11 42.6 5.8 3.1e-07 30.1 0.0 3.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.28 OQS06761.1 - 8.9e-11 41.1 5.2 2e-05 24.2 0.1 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 OQS06761.1 - 6.7e-10 38.3 4.1 0.00079 19.4 0.1 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 OQS06761.1 - 1.5e-07 30.9 1.7 0.00055 19.8 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 OQS06761.1 - 3.3e-07 30.0 2.4 9.9e-05 22.3 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.6 OQS06761.1 - 0.00036 21.0 0.5 0.54 11.0 0.1 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 OQS06761.1 - 0.046 14.4 0.1 0.6 10.8 0.1 2.3 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 OQS06761.1 - 0.085 13.7 0.4 10 7.3 0.0 3.5 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_MalT PF17874.1 OQS06761.1 - 0.17 11.2 5.3 0.25 10.6 5.3 1.1 1 0 0 1 1 1 0 MalT-like TPR region Rapsyn_N PF10579.9 OQS06761.1 - 0.22 11.7 0.6 1.9 8.6 0.1 2.3 1 1 1 2 2 2 0 Rapsyn N-terminal myristoylation and linker region Globin PF00042.22 OQS06762.1 - 0.0055 17.2 0.1 0.016 15.8 0.1 1.8 1 1 0 1 1 1 1 Globin PMM PF03332.13 OQS06763.1 - 5e-106 353.4 1.2 5.8e-106 353.2 1.2 1.0 1 0 0 1 1 1 1 Eukaryotic phosphomannomutase Hydrolase_3 PF08282.12 OQS06763.1 - 2.2e-08 34.1 0.3 5.2e-08 32.9 0.3 1.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HSF_DNA-bind PF00447.17 OQS06764.1 - 6.4e-21 74.8 5.0 1.4e-20 73.7 5.0 1.6 1 0 0 1 1 1 1 HSF-type DNA-binding Ribosomal_S26e PF01283.19 OQS06765.1 - 1.5e-48 163.7 8.0 1.7e-48 163.6 8.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S26e PPR_2 PF13041.6 OQS06766.1 - 3.5e-36 123.2 7.3 2.9e-06 27.4 0.1 11.9 8 3 5 13 13 13 8 PPR repeat family PPR PF01535.20 OQS06766.1 - 4.8e-21 73.5 8.7 0.19 12.0 0.2 12.9 13 0 0 13 13 13 5 PPR repeat PPR_3 PF13812.6 OQS06766.1 - 6.6e-19 67.7 4.3 0.003 17.6 0.0 10.1 8 2 3 11 11 11 5 Pentatricopeptide repeat domain PPR_long PF17177.4 OQS06766.1 - 4.8e-10 39.2 4.8 0.022 14.1 0.0 6.3 2 2 4 6 6 6 3 Pentacotripeptide-repeat region of PRORP TPR_14 PF13428.6 OQS06766.1 - 1.6e-05 25.3 1.9 24 6.1 0.0 6.6 5 1 1 6 6 6 0 Tetratricopeptide repeat TPR_6 PF13174.6 OQS06766.1 - 3.9e-05 24.0 3.4 18 6.3 0.0 6.5 7 0 0 7 7 6 0 Tetratricopeptide repeat TPR_19 PF14559.6 OQS06766.1 - 0.001 19.5 3.6 2.9 8.4 0.2 5.2 4 1 1 5 5 4 1 Tetratricopeptide repeat COX5A PF02284.16 OQS06766.1 - 0.02 14.9 0.3 3.2 7.8 0.0 3.5 2 1 1 3 3 3 0 Cytochrome c oxidase subunit Va TPR_2 PF07719.17 OQS06766.1 - 0.062 13.4 0.3 19 5.7 0.0 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.6 OQS06766.1 - 0.066 13.5 0.5 2.6 8.4 0.0 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat Clathrin PF00637.20 OQS06766.1 - 0.092 12.6 6.0 3.3 7.6 0.3 4.7 3 1 1 4 4 4 0 Region in Clathrin and VPS tRNA-synt_2b PF00587.25 OQS06767.1 - 1.8e-39 135.5 0.0 2.6e-39 135.0 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.22 OQS06767.1 - 7e-19 68.0 5.0 1.5e-18 67.0 5.0 1.5 1 0 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain Oxidored_FMN PF00724.20 OQS06767.1 - 0.073 12.3 0.4 0.11 11.7 0.4 1.2 1 0 0 1 1 1 0 NADH:flavin oxidoreductase / NADH oxidase family Slu7 PF11708.8 OQS06768.1 - 2.5e-93 312.7 13.1 2.5e-93 312.7 13.1 2.2 2 0 0 2 2 2 1 Pre-mRNA splicing Prp18-interacting factor DUF4050 PF13259.6 OQS06768.1 - 0.016 15.6 1.1 0.016 15.6 1.1 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF4050) zf-CCHC_4 PF14392.6 OQS06768.1 - 0.022 14.5 0.7 0.047 13.4 0.7 1.5 1 0 0 1 1 1 0 Zinc knuckle UCR_hinge PF02320.16 OQS06769.1 - 6e-18 64.8 2.2 7.3e-18 64.5 2.2 1.1 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase hinge protein TSCPD PF12637.7 OQS06769.1 - 0.024 14.9 1.4 0.035 14.4 1.4 1.3 1 1 0 1 1 1 0 TSCPD domain LRR_6 PF13516.6 OQS06770.1 - 7.7e-15 53.6 17.7 0.076 13.1 0.1 10.6 11 0 0 11 11 11 4 Leucine Rich repeat LRR_4 PF12799.7 OQS06770.1 - 1.2e-11 44.6 11.0 0.0082 16.5 0.0 6.9 3 3 6 9 9 9 6 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 OQS06770.1 - 0.00012 21.8 5.9 0.054 13.3 0.0 5.0 5 1 0 5 5 5 2 Leucine rich repeat LRR_1 PF00560.33 OQS06770.1 - 0.0012 19.1 24.4 0.87 10.4 0.1 9.2 10 1 0 10 10 10 1 Leucine Rich Repeat MiAMP1 PF09117.10 OQS06770.1 - 0.0061 16.8 1.0 6.7 7.0 0.1 3.2 3 0 0 3 3 3 2 MiAMP1 SelB-wing_2 PF09106.11 OQS06770.1 - 0.05 13.8 0.1 0.15 12.3 0.1 1.8 1 0 0 1 1 1 0 Elongation factor SelB, winged helix FOG_N PF15888.5 OQS06770.1 - 0.15 12.5 0.3 0.3 11.5 0.3 1.6 1 0 0 1 1 1 0 Folded gastrulation N-terminus TFIIE_alpha PF02002.17 OQS06770.1 - 0.19 11.6 0.0 0.59 10.0 0.0 1.8 1 0 0 1 1 1 0 TFIIE alpha subunit Cys_Met_Meta_PP PF01053.20 OQS06771.1 - 6.3e-39 133.6 0.0 8e-39 133.3 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 OQS06771.1 - 6.6e-05 22.3 0.0 9.5e-05 21.7 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II CARD PF00619.21 OQS06771.1 - 0.036 14.1 0.0 0.1 12.7 0.0 1.7 1 0 0 1 1 1 0 Caspase recruitment domain 2Fe-2S_thioredx PF01257.19 OQS06772.1 - 3.3e-61 205.4 0.2 4.2e-61 205.0 0.2 1.1 1 0 0 1 1 1 1 Thioredoxin-like [2Fe-2S] ferredoxin UPF0564 PF10595.9 OQS06773.1 - 5.6e-05 22.4 58.6 5.6e-05 22.4 58.6 3.5 1 1 1 2 2 2 1 Uncharacterised protein family UPF0564 DnaJ PF00226.31 OQS06774.1 - 6.1e-13 48.7 0.7 1.6e-12 47.4 0.7 1.8 1 0 0 1 1 1 1 DnaJ domain LRR_9 PF14580.6 OQS06774.1 - 7.8e-06 25.5 0.2 4.1e-05 23.1 0.9 1.9 2 0 0 2 2 2 1 Leucine-rich repeat LRR_4 PF12799.7 OQS06774.1 - 0.00019 21.7 4.0 0.00019 21.7 4.0 3.1 3 0 0 3 3 3 1 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 OQS06774.1 - 0.0092 15.7 3.3 0.43 10.4 0.0 2.8 2 0 0 2 2 2 2 Leucine rich repeat C2 PF00168.30 OQS06775.1 - 6.1e-22 77.9 0.0 3.1e-20 72.4 0.0 2.1 2 0 0 2 2 2 2 C2 domain Aa_trans PF01490.18 OQS06777.1 - 4.2e-59 200.3 23.5 5.4e-59 199.9 23.5 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 OQS06777.1 - 1.1e-06 28.0 6.9 1.1e-06 28.0 6.9 2.4 2 1 0 2 2 2 1 Tryptophan/tyrosine permease family DUF1240 PF06836.12 OQS06777.1 - 0.54 10.8 0.1 0.54 10.8 0.1 3.0 3 1 2 5 5 5 0 Protein of unknown function (DUF1240) Pannexin_like PF12534.8 OQS06778.1 - 0.17 10.9 4.4 8.7 5.3 0.0 2.3 2 0 0 2 2 2 0 Pannexin-like TM region of LRRC8 Cyt-b5 PF00173.28 OQS06779.1 - 1e-11 44.8 0.0 2.7e-11 43.4 0.0 1.7 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Sel1 PF08238.12 OQS06779.1 - 3.2e-11 43.5 25.5 3.5e-06 27.5 0.0 8.1 8 0 0 8 8 8 3 Sel1 repeat F-box-like PF12937.7 OQS06779.1 - 0.00043 20.1 0.0 0.00095 19.0 0.0 1.6 1 0 0 1 1 1 1 F-box-like Elongin_A PF06881.11 OQS06779.1 - 0.016 15.7 0.0 0.054 14.0 0.0 1.9 1 0 0 1 1 1 0 RNA polymerase II transcription factor SIII (Elongin) subunit A F-box PF00646.33 OQS06779.1 - 0.019 14.9 0.0 0.035 14.0 0.0 1.4 1 0 0 1 1 1 0 F-box domain TPR_16 PF13432.6 OQS06779.1 - 0.045 14.4 0.7 0.045 14.4 0.7 4.2 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_10 PF13374.6 OQS06779.1 - 0.29 11.1 1.7 1.6 8.7 0.4 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.6 OQS06779.1 - 3 8.2 14.8 0.34 11.2 1.8 4.8 4 1 0 4 4 4 0 Tetratricopeptide repeat COPIIcoated_ERV PF07970.12 OQS06780.1 - 1.1e-42 146.4 0.1 1.5e-42 146.0 0.1 1.1 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 OQS06780.1 - 5.2e-22 78.0 0.1 1.1e-21 77.0 0.1 1.5 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Ricin_B_lectin PF00652.22 OQS06781.1 - 9.1e-09 35.6 10.7 1.8e-08 34.6 10.7 1.5 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain Glyco_hydro_17 PF00332.18 OQS06781.1 - 0.00012 21.8 1.1 0.00012 21.8 1.1 2.9 3 0 0 3 3 3 2 Glycosyl hydrolases family 17 CDtoxinA PF03498.14 OQS06781.1 - 0.61 9.7 8.6 0.51 9.9 1.8 2.4 1 1 1 2 2 2 0 Cytolethal distending toxin A/C domain Pkinase PF00069.25 OQS06782.1 - 3.8e-44 151.0 0.0 5.2e-44 150.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQS06782.1 - 1.2e-43 149.3 0.0 1.6e-43 148.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OQS06782.1 - 0.00018 20.4 0.6 0.00056 18.8 0.6 1.8 1 1 0 1 1 1 1 Fungal protein kinase TMEM154 PF15102.6 OQS06782.1 - 0.0029 17.5 0.2 0.0029 17.5 0.2 2.8 1 1 1 3 3 3 1 TMEM154 protein family TMEM51 PF15345.6 OQS06782.1 - 0.011 15.6 1.1 0.011 15.6 1.1 1.7 2 0 0 2 2 2 0 Transmembrane protein 51 DUF2561 PF10812.8 OQS06782.1 - 0.02 14.9 1.5 0.026 14.5 0.3 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF2561) Orf78 PF06024.12 OQS06782.1 - 0.029 14.7 0.1 0.087 13.1 0.0 1.7 2 0 0 2 2 2 0 Orf78 (ac78) EphA2_TM PF14575.6 OQS06782.1 - 0.16 12.9 0.0 0.34 11.8 0.0 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain MAP17 PF15807.5 OQS06782.1 - 0.16 12.2 0.0 0.32 11.2 0.0 1.5 1 0 0 1 1 1 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 CoatB PF10389.9 OQS06782.1 - 0.43 10.4 3.4 1.3 8.9 3.4 1.8 1 0 0 1 1 1 0 Bacteriophage coat protein B Ric8 PF10165.9 OQS06783.1 - 1.5e-17 63.8 8.8 1.6e-11 43.9 0.1 2.2 1 1 0 2 2 2 2 Guanine nucleotide exchange factor synembryn NUC130_3NT PF08158.12 OQS06783.1 - 0.17 12.3 4.9 1.5 9.2 0.6 3.2 2 1 1 3 3 3 0 NUC130/3NT domain Ist1 PF03398.14 OQS06784.1 - 7.2e-59 198.4 3.9 8.9e-59 198.1 3.9 1.1 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway Scramblase PF03803.15 OQS06785.1 - 1e-06 28.2 0.5 0.032 13.5 0.0 2.9 3 0 0 3 3 3 2 Scramblase Pkinase_Tyr PF07714.17 OQS06785.1 - 0.00045 19.6 0.1 0.036 13.3 0.0 2.2 1 1 1 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 OQS06785.1 - 0.012 15.0 0.1 0.34 10.2 0.0 2.5 2 1 1 3 3 3 0 Protein kinase domain DUF2628 PF10947.8 OQS06786.1 - 0.065 13.6 2.3 2.8 8.4 0.1 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF2628) DUF1240 PF06836.12 OQS06787.1 - 6.1 7.4 6.5 14 6.3 0.1 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF1240) Pkinase_Tyr PF07714.17 OQS06788.1 - 6.7e-15 55.1 0.0 7.2e-12 45.1 0.0 2.0 1 1 1 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 OQS06788.1 - 2.4e-12 46.8 0.1 2e-11 43.8 0.1 1.9 1 1 1 2 2 2 2 Protein kinase domain Cut8 PF08559.10 OQS06788.1 - 0.085 12.5 0.0 0.086 12.4 0.0 1.1 1 0 0 1 1 1 0 Cut8, nuclear proteasome tether protein Pkinase PF00069.25 OQS06789.1 - 1.3e-33 116.5 0.0 2.7e-32 112.2 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQS06789.1 - 1.5e-33 116.2 0.0 3.4e-32 111.7 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OQS06789.1 - 2.4e-05 23.3 0.0 2.9e-05 23.0 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 OQS06789.1 - 0.0014 18.6 0.0 0.0026 17.7 0.0 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family Adeno_E3_CR2 PF02439.15 OQS06789.1 - 0.0036 17.0 0.9 0.0048 16.6 0.0 1.6 2 0 0 2 2 1 1 Adenovirus E3 region protein CR2 Protocadherin PF08374.11 OQS06789.1 - 0.0071 16.4 0.0 0.013 15.5 0.0 1.4 1 0 0 1 1 1 1 Protocadherin Kinase-like PF14531.6 OQS06789.1 - 0.012 15.0 0.0 0.028 13.8 0.0 1.6 2 0 0 2 2 2 0 Kinase-like DUF5305 PF17231.2 OQS06789.1 - 0.029 13.8 0.0 0.051 13.0 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5305) DUF4755 PF15947.5 OQS06789.1 - 0.032 14.2 0.0 0.057 13.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4755) Haspin_kinase PF12330.8 OQS06789.1 - 0.053 12.5 0.1 0.13 11.1 0.1 1.5 1 1 1 2 2 2 0 Haspin like kinase domain Syndecan PF01034.20 OQS06789.1 - 0.1 12.5 0.0 0.25 11.3 0.0 1.6 1 0 0 1 1 1 0 Syndecan domain Ferrochelatase PF00762.19 OQS06790.1 - 2.2e-107 358.8 0.0 2.5e-107 358.6 0.0 1.0 1 0 0 1 1 1 1 Ferrochelatase CbiX PF01903.17 OQS06790.1 - 5e-05 23.6 0.0 0.017 15.4 0.0 2.9 3 0 0 3 3 3 2 CbiX Fer4_14 PF13394.6 OQS06790.1 - 0.13 12.4 0.0 0.36 11.0 0.0 1.7 1 0 0 1 1 1 0 4Fe-4S single cluster domain EF-hand_7 PF13499.6 OQS06791.1 - 6.5e-17 61.8 4.6 1e-09 38.7 1.2 2.8 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 OQS06791.1 - 1.2e-15 55.8 4.6 1.2e-06 27.6 0.2 3.9 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.6 OQS06791.1 - 1.3e-12 46.5 3.6 4.5e-06 26.2 0.1 4.4 4 1 0 4 4 4 3 EF-hand domain EF-hand_5 PF13202.6 OQS06791.1 - 1.2e-11 43.5 1.9 6.6e-05 22.2 0.2 3.5 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.6 OQS06791.1 - 1.5e-08 34.3 2.6 1.5e-05 24.7 1.6 3.2 2 1 1 3 3 3 2 EF-hand domain pair CCB2_CCB4 PF11152.8 OQS06791.1 - 0.033 13.5 0.0 0.045 13.1 0.0 1.2 1 0 0 1 1 1 0 Cofactor assembly of complex C subunit B, CCB2/CCB4 Pkinase PF00069.25 OQS06792.1 - 2.2e-65 220.6 0.0 2.6e-65 220.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQS06792.1 - 3.5e-28 98.6 0.0 5.1e-28 98.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OQS06792.1 - 0.0012 18.2 0.0 0.0036 16.7 0.0 1.7 1 1 0 1 1 1 1 Kinase-like APH PF01636.23 OQS06792.1 - 0.12 12.3 0.0 0.19 11.7 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family RIO1 PF01163.22 OQS06792.1 - 0.14 11.8 0.1 0.26 10.9 0.0 1.5 2 0 0 2 2 2 0 RIO1 family CelTOS PF18659.1 OQS06792.1 - 0.17 12.3 0.0 0.3 11.5 0.0 1.3 1 0 0 1 1 1 0 Cell-traversal protein for ookinetes and sporozoites LMWPc PF01451.21 OQS06792.1 - 0.2 12.0 0.0 0.32 11.4 0.0 1.3 1 0 0 1 1 1 0 Low molecular weight phosphotyrosine protein phosphatase FtsJ PF01728.19 OQS06793.1 - 8.3e-69 231.2 0.2 1.6e-68 230.3 0.1 1.5 2 0 0 2 2 2 1 FtsJ-like methyltransferase NMT1 PF09084.11 OQS06793.1 - 1.4e-67 227.8 0.0 2e-67 227.3 0.0 1.2 1 0 0 1 1 1 1 NMT1/THI5 like NMT1_2 PF13379.6 OQS06793.1 - 0.0007 19.4 0.1 0.0055 16.4 0.0 2.1 2 0 0 2 2 2 1 NMT1-like family Synaptonemal_3 PF15191.6 OQS06794.1 - 0.012 15.4 1.6 0.46 10.3 0.1 2.5 2 0 0 2 2 2 0 Synaptonemal complex central element protein 3 Peptidase_S49_N PF08496.10 OQS06794.1 - 5.1 7.1 10.0 6.9 6.7 1.5 2.6 2 0 0 2 2 2 0 Peptidase family S49 N-terminal Med15 PF09606.10 OQS06794.1 - 9 4.8 38.0 14 4.2 38.0 1.3 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal PfkB PF00294.24 OQS06795.1 - 6.1e-24 84.8 0.0 9e-24 84.3 0.0 1.2 1 0 0 1 1 1 1 pfkB family carbohydrate kinase SIS PF01380.22 OQS06795.1 - 1.7e-18 66.7 0.0 6e-18 65.0 0.0 1.8 2 0 0 2 2 2 1 SIS domain SIS_2 PF13580.6 OQS06795.1 - 1.7e-05 24.9 0.0 0.24 11.4 0.0 2.6 1 1 1 2 2 2 2 SIS domain ribosomal_L24 PF17136.4 OQS06796.1 - 1.7e-16 60.4 0.0 3.1e-16 59.5 0.0 1.4 1 0 0 1 1 1 1 Ribosomal proteins 50S L24/mitochondrial 39S L24 KOW PF00467.29 OQS06796.1 - 1.4e-07 31.2 4.7 2.4e-07 30.5 4.7 1.4 1 0 0 1 1 1 1 KOW motif DUF3912 PF13051.6 OQS06796.1 - 0.025 14.8 0.1 0.044 14.0 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3912) EF-hand_1 PF00036.32 OQS06797.1 - 0.00041 19.7 0.0 0.0014 18.0 0.0 2.0 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 OQS06797.1 - 0.0082 16.0 0.0 0.033 14.1 0.0 2.1 1 0 0 1 1 1 1 EF-hand domain EF-hand_7 PF13499.6 OQS06797.1 - 0.016 15.6 0.1 0.067 13.6 0.1 2.1 1 0 0 1 1 1 0 EF-hand domain pair EF-hand_5 PF13202.6 OQS06797.1 - 0.03 13.8 0.0 0.11 12.1 0.0 2.0 1 0 0 1 1 1 0 EF hand EF-hand_8 PF13833.6 OQS06797.1 - 0.079 12.8 0.1 0.43 10.5 0.0 2.3 2 0 0 2 2 2 0 EF-hand domain pair Il2rg PF15874.5 OQS06798.1 - 5e-05 23.5 0.6 8.7e-05 22.7 0.1 1.7 2 1 1 3 3 3 1 Putative Interleukin 2 receptor, gamma chain DUF3490 PF11995.8 OQS06798.1 - 0.0089 15.9 0.0 0.011 15.5 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3490) DUF1640 PF07798.11 OQS06798.1 - 0.011 15.7 0.5 0.017 15.2 0.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1640) NPV_P10 PF05531.12 OQS06798.1 - 0.081 13.4 0.1 0.13 12.7 0.1 1.5 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein TMP-TENI PF02581.17 OQS06799.1 - 1.5e-49 167.8 3.9 1.8e-49 167.5 3.9 1.1 1 0 0 1 1 1 1 Thiamine monophosphate synthase DUF561 PF04481.12 OQS06799.1 - 0.00031 20.0 7.0 0.00055 19.2 1.3 2.7 1 1 0 2 2 2 2 Protein of unknown function (DUF561) Dev_Cell_Death PF10539.9 OQS06800.1 - 1.3e-20 73.6 0.0 2.4e-20 72.7 0.0 1.4 1 0 0 1 1 1 1 Development and cell death domain zf-CCCH PF00642.24 OQS06800.1 - 1.4e-17 63.1 24.5 7.8e-10 38.4 2.6 4.1 4 0 0 4 4 4 3 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 OQS06800.1 - 4.1e-16 58.4 40.0 1.4e-06 28.2 4.6 5.1 5 0 0 5 5 5 3 Zinc finger domain YTH PF04146.15 OQS06800.1 - 2.6e-11 43.7 0.1 1.6e-10 41.2 0.1 2.0 1 1 0 1 1 1 1 YT521-B-like domain zf-CCCH_4 PF18044.1 OQS06800.1 - 1.2e-09 37.8 27.5 1e-05 25.2 0.6 4.5 4 0 0 4 4 4 3 CCCH-type zinc finger Torus PF16131.5 OQS06800.1 - 2.8e-09 37.7 16.4 0.00014 22.5 0.3 3.4 2 1 0 3 3 3 3 Torus domain zf-CCCH_2 PF14608.6 OQS06800.1 - 1.5e-08 34.8 29.0 0.00099 19.5 3.2 4.8 4 0 0 4 4 4 3 RNA-binding, Nab2-type zinc finger zf-CCCH_3 PF15663.5 OQS06800.1 - 0.016 15.4 16.7 0.052 13.8 3.2 3.3 1 1 1 3 3 3 0 Zinc-finger containing family KH_1 PF00013.29 OQS06800.1 - 0.1 12.4 0.1 0.21 11.5 0.1 1.5 1 0 0 1 1 1 0 KH domain AAA PF00004.29 OQS06801.1 - 7.7e-39 133.1 0.0 1.5e-38 132.2 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 OQS06801.1 - 6.9e-09 35.4 0.1 7.1e-08 32.1 0.1 2.3 1 1 1 2 2 2 1 AAA+ lid domain Vps4_C PF09336.10 OQS06801.1 - 3.6e-08 33.3 1.9 7.3e-07 29.1 0.0 3.0 3 0 0 3 3 3 1 Vps4 C terminal oligomerisation domain AAA_5 PF07728.14 OQS06801.1 - 1.2e-06 28.6 0.1 3.9e-06 26.9 0.1 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 OQS06801.1 - 1.4e-06 28.1 0.0 2.7e-06 27.2 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 OQS06801.1 - 0.00031 21.0 1.0 0.015 15.6 0.8 2.8 1 1 0 1 1 1 1 AAA domain AAA_2 PF07724.14 OQS06801.1 - 0.0011 19.1 0.0 0.0025 17.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) TIP49 PF06068.13 OQS06801.1 - 0.0016 17.7 0.1 0.0045 16.2 0.1 1.7 1 1 0 1 1 1 1 TIP49 P-loop domain AAA_16 PF13191.6 OQS06801.1 - 0.0056 17.1 1.0 0.082 13.3 0.9 2.5 1 1 1 2 2 2 1 AAA ATPase domain AAA_14 PF13173.6 OQS06801.1 - 0.019 15.0 0.0 0.083 12.9 0.0 2.1 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 OQS06801.1 - 0.026 14.3 0.0 0.062 13.0 0.0 1.7 1 0 0 1 1 1 0 IstB-like ATP binding protein Zot PF05707.12 OQS06801.1 - 0.092 12.4 0.0 1.1 8.8 0.0 2.4 2 1 0 2 2 2 0 Zonular occludens toxin (Zot) Mg_chelatase PF01078.21 OQS06801.1 - 0.096 12.0 0.3 0.19 11.1 0.3 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_18 PF13238.6 OQS06801.1 - 0.14 12.7 0.1 0.48 11.0 0.0 1.9 2 0 0 2 2 2 0 AAA domain Sigma54_activat PF00158.26 OQS06801.1 - 0.15 11.7 0.1 4.4 7.0 0.0 2.2 2 0 0 2 2 2 0 Sigma-54 interaction domain ATPase PF06745.13 OQS06801.1 - 0.32 10.3 2.6 3.3 7.0 0.3 2.5 2 1 1 3 3 3 0 KaiC AAA_25 PF13481.6 OQS06801.1 - 0.39 10.3 2.2 5.3 6.6 0.3 2.6 2 1 1 3 3 3 0 AAA domain PLAC8 PF04749.17 OQS06802.1 - 8.4e-78 257.7 54.6 9e-20 71.5 7.8 5.6 5 0 0 5 5 5 5 PLAC8 family Spc7_C2 PF15577.6 OQS06802.1 - 0.00059 19.9 3.3 5.2 7.2 0.1 4.2 4 0 0 4 4 4 1 Spc7_C2 CRPV_capsid PF08762.10 OQS06802.1 - 0.036 13.7 0.1 19 4.8 0.0 3.1 3 0 0 3 3 3 0 CRPV capsid protein like DUF4064 PF13273.6 OQS06802.1 - 0.059 13.6 0.3 0.059 13.6 0.3 4.9 5 1 0 5 5 5 0 Protein of unknown function (DUF4064) RecA PF00154.21 OQS06802.1 - 1.1 8.6 2.9 14 5.0 0.0 3.3 4 0 0 4 4 4 0 recA bacterial DNA recombination protein Virul_fac_BrkB PF03631.15 OQS06802.1 - 7.5 6.1 16.5 3.1 7.4 0.6 4.3 5 0 0 5 5 5 0 Virulence factor BrkB Endosulfine PF04667.17 OQS06803.1 - 5e-31 106.7 4.0 2e-09 37.4 0.0 4.2 3 1 1 4 4 4 4 cAMP-regulated phosphoprotein/endosulfine conserved region T6SS-SciN PF12790.7 OQS06803.1 - 0.016 14.9 1.0 36 4.1 0.0 3.6 4 0 0 4 4 4 0 Type VI secretion lipoprotein, VasD, EvfM, TssJ, VC_A0113 Phosphonate-bd PF12974.7 OQS06803.1 - 0.061 12.9 0.0 0.12 11.9 0.0 1.5 2 0 0 2 2 2 0 ABC transporter, phosphonate, periplasmic substrate-binding protein TPR_1 PF00515.28 OQS06804.1 - 2.1e-60 198.2 45.2 1.3e-05 24.8 0.0 18.5 19 1 0 19 19 19 13 Tetratricopeptide repeat TPR_2 PF07719.17 OQS06804.1 - 1.9e-52 171.2 40.4 1.4e-05 24.8 0.0 16.8 17 1 0 17 17 16 11 Tetratricopeptide repeat TPR_8 PF13181.6 OQS06804.1 - 4.3e-38 126.3 33.7 0.00094 19.2 0.0 16.5 17 0 0 17 17 17 9 Tetratricopeptide repeat TPR_11 PF13414.6 OQS06804.1 - 2.6e-37 126.2 27.4 3.1e-05 23.6 0.0 14.1 11 3 4 15 15 15 8 TPR repeat TPR_16 PF13432.6 OQS06804.1 - 2.2e-29 101.8 16.9 0.00019 22.0 0.1 8.9 7 1 0 9 9 9 6 Tetratricopeptide repeat TPR_9 PF13371.6 OQS06804.1 - 3.3e-23 81.6 16.5 0.0088 16.2 0.0 9.6 4 2 6 10 10 10 8 Tetratricopeptide repeat TPR_12 PF13424.6 OQS06804.1 - 5.4e-18 65.0 44.6 0.00081 19.6 0.7 12.2 4 2 13 17 17 17 11 Tetratricopeptide repeat TPR_19 PF14559.6 OQS06804.1 - 1.3e-17 64.0 12.8 0.037 14.5 0.0 9.2 6 3 4 10 10 10 6 Tetratricopeptide repeat TPR_17 PF13431.6 OQS06804.1 - 1.7e-17 62.5 23.3 0.0017 18.6 0.3 12.3 15 0 0 15 15 12 3 Tetratricopeptide repeat TPR_14 PF13428.6 OQS06804.1 - 1.7e-13 50.2 12.9 1.3 10.1 0.0 12.2 4 4 10 14 14 13 2 Tetratricopeptide repeat TPR_6 PF13174.6 OQS06804.1 - 1.2e-12 47.6 22.4 0.37 11.5 0.3 12.9 14 0 0 14 14 12 2 Tetratricopeptide repeat ANAPC3 PF12895.7 OQS06804.1 - 2.1e-10 40.7 29.0 0.0058 16.8 2.8 7.4 4 2 2 7 7 7 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.6 OQS06804.1 - 1.8e-08 33.8 26.3 1.2 9.4 0.1 12.3 13 0 0 13 13 12 1 Tetratricopeptide repeat TPR_15 PF13429.6 OQS06804.1 - 1e-07 31.5 5.7 0.74 9.0 0.0 7.0 3 3 6 9 9 9 2 Tetratricopeptide repeat NARP1 PF12569.8 OQS06804.1 - 0.00035 19.6 15.8 0.044 12.7 0.4 4.7 4 1 1 5 5 5 3 NMDA receptor-regulated protein 1 DUF627 PF04781.12 OQS06804.1 - 0.0037 17.3 1.5 10 6.2 0.1 4.6 3 1 1 4 4 4 0 Protein of unknown function (DUF627) DUF3856 PF12968.7 OQS06804.1 - 0.039 14.0 12.8 14 5.7 0.1 7.0 4 4 1 5 5 5 0 Domain of Unknown Function (DUF3856) MIT PF04212.18 OQS06804.1 - 0.073 13.2 21.2 12 6.0 0.1 9.5 9 1 2 11 11 10 0 MIT (microtubule interacting and transport) domain TPR_20 PF14561.6 OQS06804.1 - 0.11 12.8 9.4 0.21 11.9 0.0 4.9 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_MalT PF17874.1 OQS06804.1 - 0.21 10.9 6.1 3.9 6.7 2.1 3.5 3 0 0 3 3 3 0 MalT-like TPR region DUF3808 PF10300.9 OQS06804.1 - 0.24 10.1 8.3 0.031 13.0 0.6 3.2 3 2 2 5 5 5 0 Protein of unknown function (DUF3808) SHNi-TPR PF10516.9 OQS06804.1 - 0.46 10.0 20.8 13 5.4 0.0 8.6 10 0 0 10 10 10 0 SHNi-TPR BTAD PF03704.17 OQS06804.1 - 0.51 10.8 8.2 0.84 10.1 0.1 4.4 4 3 1 5 5 5 0 Bacterial transcriptional activator domain DUF357 PF04010.13 OQS06804.1 - 1.4 9.1 5.7 16 5.7 0.1 4.4 3 1 0 3 3 3 0 Protein of unknown function (DUF357) Vta1_C PF18097.1 OQS06804.1 - 7.7 6.3 11.6 1.5 8.6 0.1 4.9 6 0 0 6 6 5 0 Vta1 C-terminal domain Bac_globin PF01152.21 OQS06805.1 - 0.017 15.3 0.0 0.024 14.8 0.0 1.4 1 1 0 1 1 1 0 Bacterial-like globin UPRTase PF14681.6 OQS06806.1 - 1.4e-70 237.0 0.0 1.6e-70 236.7 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.27 OQS06806.1 - 0.00031 20.3 0.1 0.00057 19.4 0.1 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase domain FAD_binding_2 PF00890.24 OQS06807.1 - 3.7e-79 266.8 0.9 4.2e-79 266.6 0.9 1.0 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 OQS06807.1 - 1.8e-15 57.4 0.5 3.8e-09 36.6 0.1 2.4 2 1 0 2 2 2 2 FAD dependent oxidoreductase HI0933_like PF03486.14 OQS06807.1 - 3.7e-10 39.1 4.7 6.2e-07 28.5 0.7 3.0 2 1 0 2 2 2 2 HI0933-like protein Pyr_redox_2 PF07992.14 OQS06807.1 - 7.7e-10 38.5 0.6 9.9e-09 34.8 0.2 2.3 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 OQS06807.1 - 1.8e-09 37.5 0.2 2.6e-09 36.9 0.2 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 OQS06807.1 - 5.3e-08 33.0 0.0 2.5e-06 27.6 0.0 2.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 OQS06807.1 - 3.5e-06 26.4 0.2 0.00012 21.4 0.0 2.4 2 0 0 2 2 2 1 Thi4 family Pyr_redox PF00070.27 OQS06807.1 - 5.4e-06 26.9 0.5 0.064 13.8 0.1 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 OQS06807.1 - 3.9e-05 23.1 1.0 0.036 13.3 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 OQS06807.1 - 4.5e-05 22.7 5.6 0.0051 15.9 0.2 2.9 3 0 0 3 3 3 2 Glucose inhibited division protein A Lycopene_cycl PF05834.12 OQS06807.1 - 0.00074 18.7 0.2 0.0012 18.0 0.2 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein Mqo PF06039.15 OQS06807.1 - 0.0028 16.3 0.5 0.073 11.6 0.2 2.1 2 0 0 2 2 2 1 Malate:quinone oxidoreductase (Mqo) NAD_binding_9 PF13454.6 OQS06807.1 - 0.0057 16.7 0.6 0.092 12.7 0.6 2.4 1 1 0 1 1 1 1 FAD-NAD(P)-binding K_oxygenase PF13434.6 OQS06807.1 - 0.0064 15.7 0.0 2.5 7.1 0.0 3.0 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) AlaDh_PNT_C PF01262.21 OQS06807.1 - 0.016 14.5 0.0 0.037 13.3 0.0 1.6 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain MCM PF00493.23 OQS06808.1 - 9.8e-86 286.5 0.0 1.5e-85 285.8 0.0 1.3 1 0 0 1 1 1 1 MCM P-loop domain 4HBT PF03061.22 OQS06808.1 - 8.2e-36 122.2 1.8 5.9e-12 45.8 0.0 4.8 4 0 0 4 4 4 4 Thioesterase superfamily MCM_lid PF17855.1 OQS06808.1 - 1.9e-27 95.5 1.9 5.5e-27 94.0 1.9 1.9 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_OB PF17207.3 OQS06808.1 - 1.9e-17 63.3 1.2 4.9e-17 61.9 1.2 1.8 1 0 0 1 1 1 1 MCM OB domain Ank_2 PF12796.7 OQS06808.1 - 2.9e-10 40.6 3.0 0.00085 19.9 0.0 4.1 2 1 2 4 4 4 3 Ankyrin repeats (3 copies) AAA_5 PF07728.14 OQS06808.1 - 7.6e-09 35.7 0.0 2.9e-08 33.8 0.0 2.1 2 0 0 2 2 1 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 OQS06808.1 - 3.2e-08 33.2 0.5 1.8e-05 24.3 0.0 2.8 1 1 1 2 2 2 2 Magnesium chelatase, subunit ChlI Adeno_E3_15_3 PF03307.14 OQS06808.1 - 0.00011 22.1 0.1 0.52 10.3 0.0 2.7 2 0 0 2 2 2 2 Adenovirus 15.3kD protein in E3 region AAA_3 PF07726.11 OQS06808.1 - 0.00018 21.4 0.0 0.00069 19.5 0.0 2.1 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Ank_4 PF13637.6 OQS06808.1 - 0.00024 21.6 6.2 0.57 10.8 0.3 4.4 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Sigma54_activat PF00158.26 OQS06808.1 - 0.0022 17.7 0.0 0.02 14.6 0.0 2.2 1 1 0 1 1 1 1 Sigma-54 interaction domain Ank_3 PF13606.6 OQS06808.1 - 0.0022 18.3 6.7 51 4.9 0.0 6.2 4 1 2 6 6 5 0 Ankyrin repeat MaoC_dehydratas PF01575.19 OQS06808.1 - 0.0038 16.8 5.5 5.8 6.5 0.0 3.9 4 0 0 4 4 4 2 MaoC like domain Slp PF03843.13 OQS06808.1 - 0.033 13.6 0.0 12 5.3 0.0 2.8 2 0 0 2 2 2 0 Outer membrane lipoprotein Slp family RuvB_N PF05496.12 OQS06808.1 - 0.036 13.8 0.0 0.092 12.5 0.0 1.6 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA PF00004.29 OQS06808.1 - 0.14 12.6 0.0 0.43 11.0 0.0 1.9 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Ank_5 PF13857.6 OQS06808.1 - 3.6 8.0 7.2 68 4.0 0.3 4.7 3 2 1 5 5 5 0 Ankyrin repeats (many copies) PH PF00169.29 OQS06809.1 - 0.0047 17.4 0.0 0.01 16.3 0.0 1.5 1 0 0 1 1 1 1 PH domain PaRep2a PF07903.11 OQS06809.1 - 0.088 12.6 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 PaRep2a protein Ank_2 PF12796.7 OQS06810.1 - 8.2e-15 55.2 3.3 0.00018 22.0 0.1 4.9 3 2 0 4 4 4 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OQS06810.1 - 1.1e-09 38.3 3.0 4.5 7.7 0.0 6.8 4 1 3 7 7 7 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 OQS06810.1 - 1.4e-09 38.3 2.6 0.35 11.5 0.0 5.4 4 1 1 5 5 5 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQS06810.1 - 8.3e-06 25.8 4.4 85 4.2 0.0 7.4 8 0 0 8 8 8 0 Ankyrin repeat DUF5049 PF16468.5 OQS06810.1 - 0.055 13.4 0.4 7.9 6.5 0.1 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF5049) Ank PF00023.30 OQS06810.1 - 0.14 12.6 7.5 31 5.2 2.0 5.6 3 2 0 3 3 3 0 Ankyrin repeat tRNA-synt_1 PF00133.22 OQS06811.1 - 2.7e-178 594.0 0.0 3.1e-177 590.5 0.0 2.0 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 OQS06811.1 - 1.1e-36 126.0 0.6 2.2e-36 125.1 0.6 1.4 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 OQS06811.1 - 6.6e-14 51.4 2.5 6.1e-08 31.8 0.0 4.6 4 1 0 4 4 4 3 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.6 OQS06811.1 - 8.2e-08 32.0 0.0 1.6e-05 24.5 0.0 2.4 1 1 1 2 2 2 2 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1e PF01406.19 OQS06811.1 - 2.1e-05 24.0 0.0 0.19 11.0 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain Val_tRNA-synt_C PF10458.9 OQS06811.1 - 0.0031 17.8 1.2 0.0051 17.1 0.0 2.0 2 0 0 2 2 2 1 Valyl tRNA synthetase tRNA binding arm DUF4380 PF14315.6 OQS06811.1 - 0.045 12.7 0.5 0.17 10.8 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4380) Hist_deacetyl PF00850.19 OQS06812.1 - 6.3e-76 255.8 0.0 1.1e-75 255.0 0.0 1.4 1 0 0 1 1 1 1 Histone deacetylase domain HECT PF00632.25 OQS06813.1 - 1.4e-93 313.8 0.0 2.8e-93 312.8 0.0 1.5 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) HSP90 PF00183.18 OQS06814.1 - 6.4e-235 780.9 23.2 8e-235 780.6 23.2 1.1 1 0 0 1 1 1 1 Hsp90 protein HATPase_c PF02518.26 OQS06814.1 - 9.1e-13 48.7 0.1 1.6e-12 47.9 0.1 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 OQS06814.1 - 8.2e-09 35.4 0.1 1.9e-08 34.2 0.1 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase TRIQK PF15168.6 OQS06814.1 - 0.75 9.7 0.0 0.75 9.7 0.0 2.3 2 0 0 2 2 2 0 Triple QxxK/R motif-containing protein family DUF2052 PF09747.9 OQS06814.1 - 2 8.5 14.0 0.065 13.4 7.0 2.0 3 0 0 3 3 3 0 Coiled-coil domain containing protein (DUF2052) COX_ARM PF06481.14 OQS06814.1 - 2.7 8.0 4.4 28 4.7 0.0 3.1 3 0 0 3 3 3 0 COX Aromatic Rich Motif Ephrin_rec_like PF07699.13 OQS06816.1 - 6.5e-16 57.8 39.9 2.6e-06 27.1 6.5 4.3 1 1 4 5 5 5 5 Putative ephrin-receptor like Erf4 PF10256.9 OQS06816.1 - 0.02 15.0 0.0 0.33 11.1 0.0 2.5 2 0 0 2 2 2 0 Golgin subfamily A member 7/ERF4 family TNFR_c6 PF00020.18 OQS06816.1 - 5.6 7.5 25.7 0.19 12.1 0.9 5.0 2 1 4 6 6 6 0 TNFR/NGFR cysteine-rich region Abhydrolase_6 PF12697.7 OQS06817.1 - 8.9e-07 29.7 0.0 0.049 14.2 0.0 2.5 2 0 0 2 2 2 2 Alpha/beta hydrolase family LCAT PF02450.15 OQS06817.1 - 1.4e-05 24.5 0.6 0.069 12.3 0.0 2.2 2 0 0 2 2 2 2 Lecithin:cholesterol acyltransferase Thioesterase PF00975.20 OQS06817.1 - 5.9e-05 23.3 0.1 0.31 11.1 0.0 2.3 2 0 0 2 2 2 2 Thioesterase domain Palm_thioest PF02089.15 OQS06817.1 - 6e-05 23.0 0.0 0.045 13.6 0.0 2.3 2 0 0 2 2 2 2 Palmitoyl protein thioesterase Abhydrolase_1 PF00561.20 OQS06817.1 - 0.0035 17.0 0.6 0.72 9.4 0.1 2.5 2 0 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 OQS06817.1 - 0.02 14.2 0.0 6.5 5.9 0.0 2.3 2 0 0 2 2 2 0 Serine aminopeptidase, S33 PAF-AH_p_II PF03403.13 OQS06817.1 - 0.041 12.4 0.0 1.5 7.2 0.0 2.2 2 0 0 2 2 2 0 Platelet-activating factor acetylhydrolase, isoform II Lipase_3 PF01764.25 OQS06817.1 - 0.082 12.8 0.1 8.1 6.3 0.0 2.4 2 0 0 2 2 2 0 Lipase (class 3) Abhydrolase_1 PF00561.20 OQS06818.1 - 3.9e-09 36.5 0.1 5.7e-08 32.7 0.0 2.3 2 0 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 OQS06818.1 - 6e-06 25.7 0.0 0.0032 16.8 0.0 2.8 2 1 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_4 PF08386.10 OQS06818.1 - 0.00064 19.8 0.0 0.0014 18.7 0.0 1.6 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_6 PF12697.7 OQS06818.1 - 0.06 13.9 0.0 0.31 11.6 0.0 2.0 1 1 0 1 1 1 0 Alpha/beta hydrolase family SUR7 PF06687.12 OQS06818.1 - 0.88 9.2 4.7 2.1 7.9 0.0 3.2 4 0 0 4 4 4 0 SUR7/PalI family MFS_1 PF07690.16 OQS06819.1 - 1.2e-31 109.9 30.3 1.2e-31 109.9 30.3 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily OATP PF03137.20 OQS06819.1 - 5.3e-25 87.7 20.2 6.5e-17 61.0 1.2 4.2 1 1 3 4 4 4 2 Organic Anion Transporter Polypeptide (OATP) family Sugar_tr PF00083.24 OQS06819.1 - 7.8e-10 38.2 24.6 2.8e-08 33.1 24.6 2.8 1 1 0 1 1 1 1 Sugar (and other) transporter cwf21 PF08312.12 OQS06820.1 - 7.5e-17 61.2 9.8 7.5e-17 61.2 9.8 2.3 2 1 0 2 2 2 1 cwf21 domain Abhydrolase_6 PF12697.7 OQS06821.1 - 0.004 17.8 0.0 0.0077 16.9 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.20 OQS06821.1 - 0.025 14.7 0.0 0.045 13.9 0.0 1.3 1 0 0 1 1 1 0 Thioesterase domain LCAT PF02450.15 OQS06821.1 - 0.039 13.1 0.0 0.085 12.0 0.0 1.6 2 0 0 2 2 2 0 Lecithin:cholesterol acyltransferase PGF-CTERM PF18204.1 OQS06821.1 - 0.15 12.0 1.1 0.31 11.1 1.1 1.5 1 0 0 1 1 1 0 PGF-CTERM motif Palm_thioest PF02089.15 OQS06821.1 - 0.16 11.8 0.0 0.68 9.7 0.0 1.9 2 0 0 2 2 2 0 Palmitoyl protein thioesterase ELP6 PF09807.9 OQS06822.1 - 4e-37 128.0 0.4 4.9e-37 127.7 0.4 1.0 1 0 0 1 1 1 1 Elongation complex protein 6 Elong_Iki1 PF10483.9 OQS06822.1 - 2.2e-07 30.7 0.1 3.1e-07 30.2 0.1 1.2 1 0 0 1 1 1 1 Elongator subunit Iki1 ATPase PF06745.13 OQS06822.1 - 0.0026 17.1 0.0 0.0037 16.6 0.0 1.2 1 0 0 1 1 1 1 KaiC zf-4CXXC_R1 PF10497.9 OQS06823.1 - 0.036 14.3 5.7 0.047 13.9 3.7 2.1 2 0 0 2 2 2 0 Zinc-finger domain of monoamine-oxidase A repressor R1 Peptidase_S28 PF05577.12 OQS06824.1 - 2.7e-101 339.5 0.6 3.2e-101 339.3 0.6 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase S28 Peptidase_S37 PF05576.11 OQS06824.1 - 0.0011 17.7 0.0 0.0017 17.1 0.0 1.2 1 0 0 1 1 1 1 PS-10 peptidase S37 Hydrolase_4 PF12146.8 OQS06824.1 - 0.025 13.9 0.0 0.5 9.6 0.0 2.1 1 1 1 2 2 2 0 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 OQS06824.1 - 0.098 12.1 0.0 0.17 11.3 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family RRM_1 PF00076.22 OQS06825.1 - 9.1e-16 57.4 0.1 1.6e-15 56.7 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 OQS06825.1 - 0.0035 17.4 0.4 0.0062 16.6 0.4 1.4 1 0 0 1 1 1 1 RNA binding motif NOP5NT PF08156.13 OQS06825.1 - 0.018 15.4 0.3 0.18 12.3 0.1 2.5 1 1 1 2 2 2 0 NOP5NT (NUC127) domain Peptidase_M1 PF01433.20 OQS06826.1 - 5e-83 278.0 2.0 9.6e-83 277.0 2.0 1.5 1 0 0 1 1 1 1 Peptidase family M1 domain ERAP1_C PF11838.8 OQS06826.1 - 4.2e-59 200.6 2.7 3.5e-58 197.6 1.7 2.4 3 0 0 3 3 3 1 ERAP1-like C-terminal domain Peptidase_M1_N PF17900.1 OQS06826.1 - 6e-39 134.2 0.0 1.1e-38 133.3 0.0 1.4 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain Biotin_lipoyl PF00364.22 OQS06827.1 - 3.1e-47 158.3 11.4 1.6e-18 66.3 2.1 3.3 3 0 0 3 3 3 3 Biotin-requiring enzyme bZIP_2 PF07716.15 OQS06827.1 - 1.6e-05 24.9 5.2 2.5e-05 24.3 5.2 1.3 1 0 0 1 1 1 1 Basic region leucine zipper Biotin_lipoyl_2 PF13533.6 OQS06827.1 - 1.6e-05 24.6 16.2 0.0037 17.1 1.4 5.1 3 2 2 5 5 5 2 Biotin-lipoyl like GCV_H PF01597.19 OQS06827.1 - 2.1e-05 24.4 4.0 0.87 9.5 0.4 3.4 3 0 0 3 3 3 2 Glycine cleavage H-protein bZIP_1 PF00170.21 OQS06827.1 - 0.00013 22.0 2.5 0.00026 21.0 2.5 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_Maf PF03131.17 OQS06827.1 - 0.00062 20.2 3.1 0.0012 19.3 3.1 1.4 1 0 0 1 1 1 1 bZIP Maf transcription factor DUF2118 PF09891.9 OQS06827.1 - 0.001 19.0 5.7 0.92 9.4 0.0 3.7 3 1 1 4 4 4 2 Uncharacterized protein conserved in archaea (DUF2118) ABC_tran_CTD PF16326.5 OQS06827.1 - 0.075 13.3 0.2 0.14 12.5 0.2 1.4 1 0 0 1 1 1 0 ABC transporter C-terminal domain Ufd2P_core PF10408.9 OQS06827.1 - 0.084 11.5 0.6 6.8 5.2 0.2 2.7 3 0 0 3 3 3 0 Ubiquitin elongating factor core QRPTase_N PF02749.16 OQS06827.1 - 0.16 12.0 1.3 11 6.2 0.0 3.0 3 0 0 3 3 3 0 Quinolinate phosphoribosyl transferase, N-terminal domain PYNP_C PF07831.13 OQS06827.1 - 0.83 9.3 4.1 7.7 6.3 0.2 3.5 3 1 1 4 4 4 0 Pyrimidine nucleoside phosphorylase C-terminal domain HlyD_3 PF13437.6 OQS06827.1 - 8.8 7.1 11.8 49 4.7 0.0 4.3 3 2 2 5 5 5 0 HlyD family secretion protein Bmt2 PF11968.8 OQS06828.1 - 7.1e-49 166.6 0.0 1.3e-48 165.8 0.0 1.4 1 0 0 1 1 1 1 25S rRNA (adenine(2142)-N(1))-methyltransferase, Bmt2 Pkinase_Tyr PF07714.17 OQS06828.1 - 2.1e-24 86.2 0.0 3.9e-24 85.3 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OQS06828.1 - 1.1e-21 77.5 0.0 1.9e-21 76.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain LRR_8 PF13855.6 OQS06828.1 - 2.7e-19 68.7 27.9 7.8e-07 28.8 2.6 6.2 4 2 1 5 5 5 5 Leucine rich repeat LRR_4 PF12799.7 OQS06828.1 - 3.8e-16 58.9 36.3 0.00043 20.6 0.2 7.9 5 2 2 7 7 7 7 Leucine Rich repeats (2 copies) START PF01852.19 OQS06828.1 - 6.3e-05 22.5 0.0 0.00015 21.3 0.0 1.5 1 0 0 1 1 1 1 START domain Methyltransf_23 PF13489.6 OQS06828.1 - 7.3e-05 22.7 0.0 0.00017 21.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OQS06828.1 - 0.00025 21.7 0.1 0.0025 18.5 0.0 2.7 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 OQS06828.1 - 0.00029 21.4 0.0 0.00096 19.8 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain FYVE PF01363.21 OQS06828.1 - 0.0023 18.0 9.8 0.0058 16.7 9.8 1.7 1 0 0 1 1 1 1 FYVE zinc finger Methyltransf_25 PF13649.6 OQS06828.1 - 0.0087 16.7 0.0 0.033 14.9 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain LRR_6 PF13516.6 OQS06828.1 - 0.014 15.4 21.3 6.2 7.1 0.1 8.7 8 1 1 9 9 9 0 Leucine Rich repeat LRR_9 PF14580.6 OQS06828.1 - 0.2 11.2 4.5 2.4 7.6 0.2 3.3 2 1 1 3 3 3 0 Leucine-rich repeat LRR_5 PF13306.6 OQS06829.1 - 0.00032 20.7 0.1 0.00055 19.9 0.1 1.4 1 0 0 1 1 1 1 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 OQS06829.1 - 0.035 13.9 2.3 0.04 13.7 0.2 2.1 2 0 0 2 2 2 0 Leucine rich repeat LRR_4 PF12799.7 OQS06829.1 - 0.15 12.6 4.7 1.9 9.0 0.1 2.7 2 0 0 2 2 2 0 Leucine Rich repeats (2 copies) Tyrosinase PF00264.20 OQS06830.1 - 6.6e-24 85.4 0.8 5.8e-23 82.4 0.8 2.1 1 1 0 1 1 1 1 Common central domain of tyrosinase Hydrolase PF00702.26 OQS06831.1 - 1.3e-11 45.2 0.1 3.2e-11 43.9 0.1 1.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 OQS06831.1 - 3.2e-11 44.0 0.0 8.2e-11 42.6 0.0 1.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.12 OQS06831.1 - 3.7e-07 29.8 0.0 6.7e-07 28.9 0.0 1.4 1 1 0 1 1 1 1 Putative Phosphatase UMPH-1 PF05822.12 OQS06831.1 - 0.0014 18.2 0.0 0.002 17.7 0.0 1.3 1 1 0 1 1 1 1 Pyrimidine 5'-nucleotidase (UMPH-1) HAD_2 PF13419.6 OQS06831.1 - 0.01 15.9 0.1 4.1 7.5 0.0 2.6 2 1 0 2 2 2 0 Haloacid dehalogenase-like hydrolase Acid_phosphat_B PF03767.14 OQS06831.1 - 0.083 12.5 0.1 9.1 5.8 0.0 2.5 2 1 0 2 2 2 0 HAD superfamily, subfamily IIIB (Acid phosphatase) Tub PF01167.18 OQS06832.1 - 1.8e-49 168.7 0.1 6.5e-49 166.9 0.1 1.8 1 1 0 1 1 1 1 Tub family DUF3527 PF12043.8 OQS06832.1 - 0.0015 18.2 1.0 0.0087 15.7 0.1 2.3 1 1 1 2 2 2 1 Domain of unknown function (DUF3527) BUD22 PF09073.10 OQS06832.1 - 0.15 11.4 5.2 0.22 10.8 5.2 1.2 1 0 0 1 1 1 0 BUD22 DA1-like PF12315.8 OQS06833.1 - 8.7e-37 126.5 0.0 8.4e-36 123.3 0.0 2.1 1 1 0 1 1 1 1 Protein DA1 LIM PF00412.22 OQS06833.1 - 1.9e-10 40.8 5.2 1.9e-10 40.8 5.2 3.7 2 1 3 5 5 5 1 LIM domain zf-RanBP PF00641.18 OQS06833.1 - 1.4e-05 24.3 4.8 1.4e-05 24.3 4.8 3.6 5 0 0 5 5 5 1 Zn-finger in Ran binding protein and others zf-dskA_traR PF01258.17 OQS06833.1 - 0.012 15.6 0.5 0.012 15.6 0.5 3.6 4 0 0 4 4 4 0 Prokaryotic dksA/traR C4-type zinc finger DZR PF12773.7 OQS06833.1 - 9.4 6.4 25.8 1.8e+04 -9.6 25.8 4.3 1 1 0 1 1 1 0 Double zinc ribbon SepSecS PF05889.13 OQS06834.1 - 1.7e-135 451.7 0.0 2.3e-135 451.3 0.0 1.2 1 0 0 1 1 1 1 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS Beta_elim_lyase PF01212.21 OQS06834.1 - 1.5e-05 24.4 0.0 2.7e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase Pyridoxal_deC PF00282.19 OQS06834.1 - 0.00016 20.5 0.0 0.0014 17.5 0.0 2.1 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain DASH_Duo1 PF08651.10 OQS06834.1 - 0.023 14.5 0.1 0.098 12.4 0.1 2.1 1 0 0 1 1 1 0 DASH complex subunit Duo1 Kinesin PF00225.23 OQS06835.1 - 5.5e-87 291.8 4.0 5.5e-87 291.8 4.0 2.8 3 1 0 3 3 3 1 Kinesin motor domain Ank_4 PF13637.6 OQS06835.1 - 5.9e-14 52.2 5.0 0.0013 19.3 0.4 5.4 2 1 4 6 6 6 6 Ankyrin repeats (many copies) Microtub_bd PF16796.5 OQS06835.1 - 6.2e-14 52.2 1.0 2.1e-13 50.5 0.0 2.4 2 0 0 2 2 2 1 Microtubule binding Ank_2 PF12796.7 OQS06835.1 - 9.2e-13 48.6 5.3 5.4e-06 26.9 2.2 3.0 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OQS06835.1 - 1.1e-11 44.7 1.5 0.036 14.4 0.1 4.7 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQS06835.1 - 2.1e-07 30.7 3.3 0.45 11.2 0.0 5.8 5 0 0 5 5 5 1 Ankyrin repeat Questin_oxidase PF14027.6 OQS06835.1 - 0.017 14.7 1.0 0.044 13.3 1.0 1.7 1 0 0 1 1 1 0 Questin oxidase-like Rootletin PF15035.6 OQS06835.1 - 0.13 12.2 24.3 0.29 11.1 0.9 3.5 3 0 0 3 3 3 0 Ciliary rootlet component, centrosome cohesion Ank PF00023.30 OQS06835.1 - 0.45 11.0 5.2 7.3 7.2 0.5 3.8 4 1 0 4 4 4 0 Ankyrin repeat Na_H_Exchanger PF00999.21 OQS06836.1 - 2.4e-58 197.8 36.6 3e-58 197.4 36.6 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family FeoB_C PF07664.12 OQS06836.1 - 0.55 9.9 5.9 0.4 10.4 0.2 3.5 3 0 0 3 3 3 0 Ferrous iron transport protein B C terminus CHAP PF05257.16 OQS06837.1 - 3.5e-14 53.1 0.6 6.2e-14 52.3 0.6 1.4 1 0 0 1 1 1 1 CHAP domain DUF553 PF04473.12 OQS06837.1 - 0.019 14.5 0.0 0.028 14.0 0.0 1.3 1 0 0 1 1 1 0 Transglutaminase-like domain bZIP_1 PF00170.21 OQS06838.1 - 1.2e-06 28.5 37.8 0.00094 19.2 11.7 3.9 3 0 0 3 3 3 3 bZIP transcription factor bZIP_2 PF07716.15 OQS06838.1 - 0.0022 18.0 35.3 0.0055 16.8 10.4 3.8 3 0 0 3 3 3 2 Basic region leucine zipper Popeye PF04831.13 OQS06838.1 - 0.012 15.8 0.8 5.7 7.1 0.0 2.9 3 0 0 3 3 3 0 Popeye protein conserved region SlyX PF04102.12 OQS06838.1 - 9.8 6.9 11.9 4.2 8.1 0.4 4.1 3 0 0 3 3 3 0 SlyX CLU PF13236.6 OQS06839.1 - 6.4e-73 245.2 0.0 1.2e-72 244.3 0.0 1.5 1 0 0 1 1 1 1 Clustered mitochondria eIF3_p135 PF12807.7 OQS06839.1 - 2.4e-34 118.9 0.0 8.6e-34 117.1 0.0 2.1 2 0 0 2 2 2 1 Translation initiation factor eIF3 subunit 135 CLU_N PF15044.6 OQS06839.1 - 9.8e-16 57.9 0.0 2.2e-15 56.8 0.0 1.7 1 0 0 1 1 1 1 Mitochondrial function, CLU-N-term TPR_12 PF13424.6 OQS06839.1 - 2.2e-12 47.1 17.1 9.9e-06 25.8 5.9 4.2 1 1 3 4 4 4 3 Tetratricopeptide repeat TPR_10 PF13374.6 OQS06839.1 - 3.9e-06 26.6 9.3 0.0028 17.4 0.0 4.6 4 0 0 4 4 4 3 Tetratricopeptide repeat Caprin-1_C PF12287.8 OQS06839.1 - 0.26 11.4 1.7 0.46 10.6 1.7 1.3 1 0 0 1 1 1 0 Cytoplasmic activation/proliferation-associated protein-1 C term Phosphoesterase PF04185.14 OQS06841.1 - 0.0021 17.3 3.4 0.0024 17.1 3.4 1.0 1 0 0 1 1 1 1 Phosphoesterase family SR-25 PF10500.9 OQS06841.1 - 0.23 11.1 13.6 0.3 10.7 13.6 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Ank_2 PF12796.7 OQS06843.1 - 6.1e-32 110.0 10.8 3e-13 50.2 0.5 3.6 1 1 3 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQS06843.1 - 1.3e-23 83.0 10.1 7.3e-11 42.4 0.2 4.7 4 1 2 6 6 5 4 Ankyrin repeats (many copies) PA PF02225.22 OQS06843.1 - 3.3e-23 81.5 0.3 5.8e-11 42.3 0.2 2.6 2 0 0 2 2 2 2 PA domain Ank_5 PF13857.6 OQS06843.1 - 7.4e-21 73.9 7.6 3.9e-07 30.2 0.1 4.6 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 OQS06843.1 - 3.9e-18 65.0 17.1 0.0063 16.9 0.0 6.4 6 0 0 6 6 6 5 Ankyrin repeat Ank_3 PF13606.6 OQS06843.1 - 4.1e-17 60.5 13.8 0.0013 19.0 0.1 7.2 7 1 0 7 7 6 4 Ankyrin repeat IQ PF00612.27 OQS06843.1 - 0.00034 20.2 1.4 0.016 14.9 0.1 2.7 2 0 0 2 2 2 1 IQ calmodulin-binding motif WGR PF05406.15 OQS06843.1 - 0.0045 17.0 0.1 0.01 15.8 0.1 1.6 1 0 0 1 1 1 1 WGR domain TPR_12 PF13424.6 OQS06843.1 - 0.022 15.0 0.5 0.068 13.5 0.5 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_2 PF07719.17 OQS06843.1 - 0.14 12.4 0.5 0.51 10.6 0.5 2.0 1 0 0 1 1 1 0 Tetratricopeptide repeat Spexin PF15171.6 OQS06843.1 - 0.5 10.6 3.1 1.7 8.9 3.1 1.9 1 0 0 1 1 1 0 Neuropeptide secretory protein family, NPQ, spexin Myosin_head PF00063.21 OQS06846.1 - 6.3e-231 768.3 0.2 8.5e-231 767.8 0.2 1.2 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_TH1 PF06017.13 OQS06846.1 - 3.4e-16 59.5 0.0 5.3e-13 49.1 0.0 2.6 2 0 0 2 2 2 2 Unconventional myosin tail, actin- and lipid-binding FYVE PF01363.21 OQS06846.1 - 1.5e-11 44.3 0.8 3.2e-11 43.2 0.8 1.6 1 0 0 1 1 1 1 FYVE zinc finger RsgA_GTPase PF03193.16 OQS06846.1 - 0.035 14.0 0.0 0.078 12.9 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase AAA_16 PF13191.6 OQS06846.1 - 0.067 13.6 0.7 0.18 12.1 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain DUF1682 PF07946.14 OQS06846.1 - 0.28 10.4 14.6 0.24 10.6 13.3 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1682) Pkinase PF00069.25 OQS06847.1 - 5.3e-18 65.3 0.0 1.5e-16 60.5 0.0 2.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 OQS06847.1 - 1.9e-09 36.8 0.3 3.6e-08 32.6 0.0 2.0 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 OQS06847.1 - 0.00088 19.3 0.0 0.14 12.1 0.0 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family PIP49_C PF12260.8 OQS06847.1 - 0.0069 16.0 0.0 0.021 14.5 0.0 1.7 2 0 0 2 2 2 1 Protein-kinase domain of FAM69 Pkinase_Tyr PF07714.17 OQS06847.1 - 0.016 14.5 0.0 0.081 12.2 0.0 1.9 1 1 0 1 1 1 0 Protein tyrosine kinase HSF_DNA-bind PF00447.17 OQS06848.1 - 1.8e-20 73.3 0.0 3.6e-20 72.4 0.0 1.5 1 0 0 1 1 1 1 HSF-type DNA-binding DUF3391 PF11871.8 OQS06848.1 - 0.068 13.7 3.4 0.073 13.6 1.7 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF3391) DUF3583 PF12126.8 OQS06848.1 - 6.8 6.0 7.9 0.99 8.8 2.8 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3583) CTP_transf_like PF01467.26 OQS06849.1 - 3.1e-35 121.5 0.1 6.2e-17 62.1 0.0 2.4 2 0 0 2 2 2 2 Cytidylyltransferase-like PhnA PF03831.14 OQS06849.1 - 3.4e-20 71.7 0.2 6.3e-20 70.8 0.2 1.5 1 0 0 1 1 1 1 PhnA domain PhnA_Zn_Ribbon PF08274.12 OQS06849.1 - 1.9e-08 34.1 3.5 3.9e-08 33.1 3.5 1.5 1 0 0 1 1 1 1 PhnA Zinc-Ribbon FAD_syn PF06574.12 OQS06849.1 - 0.0024 17.8 0.6 0.53 10.2 0.1 3.6 2 1 0 2 2 2 1 FAD synthetase DivIC PF04977.15 OQS06849.1 - 0.0096 15.7 0.1 0.022 14.5 0.1 1.6 1 0 0 1 1 1 1 Septum formation initiator HR1 PF02185.16 OQS06849.1 - 0.019 15.1 1.3 0.04 14.0 1.3 1.5 1 0 0 1 1 1 0 Hr1 repeat OrfB_Zn_ribbon PF07282.11 OQS06849.1 - 0.051 13.5 1.2 0.14 12.1 1.2 1.7 1 0 0 1 1 1 0 Putative transposase DNA-binding domain T2SSM PF04612.12 OQS06849.1 - 0.15 12.1 0.0 0.31 11.1 0.0 1.4 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein M TF_Zn_Ribbon PF08271.12 OQS06849.1 - 0.33 10.5 2.0 0.82 9.2 2.0 1.6 1 0 0 1 1 1 0 TFIIB zinc-binding TFIIS_C PF01096.18 OQS06849.1 - 0.48 10.3 1.7 19 5.2 0.1 2.4 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS) PADR1 PF08063.12 OQS06849.1 - 0.85 9.4 3.3 0.52 10.1 0.7 2.0 2 0 0 2 2 2 0 PADR1 (NUC008) domain Cullin PF00888.22 OQS06850.1 - 1.1e-178 595.8 0.5 1.3e-178 595.5 0.5 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 OQS06850.1 - 1.5e-23 82.6 0.8 4.2e-23 81.2 0.8 1.9 1 0 0 1 1 1 1 Cullin protein neddylation domain Tim17 PF02466.19 OQS06850.1 - 4.3e-06 27.1 0.2 1.1e-05 25.8 0.2 1.7 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Cas_Cas5d PF09704.10 OQS06850.1 - 0.024 14.5 0.0 0.062 13.2 0.0 1.7 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Cas5) B56 PF01603.20 OQS06851.1 - 1.7e-170 567.5 0.2 3.3e-170 566.5 0.2 1.5 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) WW PF00397.26 OQS06851.1 - 3.9e-41 138.8 45.6 2.3e-10 40.3 1.3 7.7 7 0 0 7 7 7 6 WW domain Ank_2 PF12796.7 OQS06851.1 - 2e-35 121.2 6.4 4.6e-11 43.1 0.1 4.8 1 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQS06851.1 - 5.7e-26 90.6 9.6 3.8e-08 33.7 0.2 7.2 4 2 3 7 7 7 6 Ankyrin repeats (many copies) Ank_5 PF13857.6 OQS06851.1 - 8.8e-22 76.9 11.8 3.9e-05 23.8 0.0 7.9 3 1 5 8 8 8 6 Ankyrin repeats (many copies) Ank PF00023.30 OQS06851.1 - 6.3e-21 73.8 17.2 0.001 19.4 0.0 9.3 10 0 0 10 10 10 6 Ankyrin repeat IQ PF00612.27 OQS06851.1 - 9.5e-20 68.5 100.8 0.00053 19.6 3.0 14.8 14 0 0 14 14 14 10 IQ calmodulin-binding motif Ank_3 PF13606.6 OQS06851.1 - 1.9e-17 61.5 12.7 0.0031 17.9 0.2 9.3 9 0 0 9 9 9 4 Ankyrin repeat PQQ PF01011.21 OQS06851.1 - 0.00078 19.3 3.3 1.9 8.6 0.0 4.4 4 0 0 4 4 4 1 PQQ enzyme repeat DUF3447 PF11929.8 OQS06851.1 - 0.017 15.1 0.0 0.066 13.2 0.0 2.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3447) Glyco_hyd_101C PF17451.2 OQS06851.1 - 0.047 14.0 23.1 3.6 7.9 0.8 5.7 1 1 4 5 5 5 0 Glycosyl hydrolase 101 beta sandwich domain PQQ_2 PF13360.6 OQS06851.1 - 0.14 11.7 3.5 4.7 6.7 0.2 2.6 1 1 1 2 2 2 0 PQQ-like domain TPR_1 PF00515.28 OQS06851.1 - 0.15 11.9 1.4 2.1 8.3 0.1 3.3 2 0 0 2 2 2 0 Tetratricopeptide repeat AAA_11 PF13086.6 OQS06851.1 - 8.9 6.0 13.6 29 4.3 13.6 1.8 1 0 0 1 1 1 0 AAA domain TIP41 PF04176.13 OQS06852.1 - 4.8e-56 188.9 0.4 6.8e-56 188.4 0.4 1.2 1 0 0 1 1 1 1 TIP41-like family FYVE PF01363.21 OQS06853.1 - 1.5e-05 25.1 16.6 3.4e-05 23.9 16.6 1.6 1 0 0 1 1 1 1 FYVE zinc finger C1_2 PF03107.16 OQS06853.1 - 0.0025 18.1 7.2 0.0025 18.1 7.2 1.9 2 0 0 2 2 2 1 C1 domain FYVE_2 PF02318.16 OQS06853.1 - 0.31 11.2 11.7 0.56 10.4 11.7 1.3 1 0 0 1 1 1 0 FYVE-type zinc finger Siva PF05458.12 OQS06853.1 - 1.1 9.0 10.6 1.5 8.5 9.4 1.8 2 0 0 2 2 2 0 Cd27 binding protein (Siva) Ion_trans PF00520.31 OQS06854.1 - 1.6e-53 181.5 31.5 1e-26 93.7 10.2 2.3 2 0 0 2 2 2 2 Ion transport protein cNMP_binding PF00027.29 OQS06854.1 - 6.6e-34 115.9 0.0 5.4e-18 64.9 0.0 2.5 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain Ion_trans_2 PF07885.16 OQS06854.1 - 5.8e-22 77.5 23.8 2.5e-11 43.4 2.0 3.3 2 1 0 2 2 2 2 Ion channel LapA_dom PF06305.11 OQS06854.1 - 0.053 13.3 0.5 5.2 7.0 0.0 2.9 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain RabGAP-TBC PF00566.18 OQS06854.1 - 0.07 12.8 1.2 2.3 7.8 0.7 2.9 2 0 0 2 2 2 0 Rab-GTPase-TBC domain a_DG1_N2 PF18424.1 OQS06854.1 - 0.077 13.1 0.0 0.22 11.6 0.0 1.7 1 0 0 1 1 1 0 Alpha-Dystroglycan N-terminal domain 2 HSF_DNA-bind PF00447.17 OQS06855.1 - 2e-09 37.9 0.0 3.3e-09 37.2 0.0 1.3 1 0 0 1 1 1 1 HSF-type DNA-binding EIF_2_alpha PF07541.12 OQS06856.1 - 1e-39 135.2 0.1 2.5e-39 134.0 0.1 1.7 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 2 alpha subunit S1 PF00575.23 OQS06856.1 - 3.5e-14 52.9 0.9 8.7e-14 51.6 0.9 1.7 1 0 0 1 1 1 1 S1 RNA binding domain Thaumatin PF00314.17 OQS06859.1 - 0.00033 20.4 3.1 1.4 8.5 0.2 3.8 2 2 2 4 4 4 4 Thaumatin family Pkinase PF00069.25 OQS06860.1 - 3.3e-57 193.9 0.0 5.1e-52 176.9 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OQS06860.1 - 1.5e-21 76.9 0.0 3.9e-18 65.7 0.0 2.8 2 1 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 OQS06860.1 - 0.0057 16.0 0.0 0.94 8.7 0.0 2.2 2 0 0 2 2 2 2 Kinase-like APH PF01636.23 OQS06860.1 - 0.057 13.3 0.1 0.14 12.1 0.1 1.6 2 0 0 2 2 2 0 Phosphotransferase enzyme family PDEase_I PF00233.19 OQS06861.1 - 6e-67 225.8 0.6 2.1e-66 224.0 0.2 2.0 2 0 0 2 2 2 1 3'5'-cyclic nucleotide phosphodiesterase GAF PF01590.26 OQS06861.1 - 3.6e-08 34.1 0.0 1e-05 26.2 0.0 2.6 2 0 0 2 2 2 2 GAF domain HD PF01966.22 OQS06861.1 - 0.0006 20.0 0.1 0.0014 18.8 0.1 1.7 1 0 0 1 1 1 1 HD domain GAF_3 PF13492.6 OQS06861.1 - 0.0015 18.9 0.0 0.026 14.9 0.0 2.4 2 0 0 2 2 2 1 GAF domain EF-hand_1 PF00036.32 OQS06862.1 - 1.9e-10 39.5 1.9 0.00021 20.6 0.1 3.8 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.6 OQS06862.1 - 4.9e-09 35.4 0.4 0.097 12.6 0.1 4.2 4 0 0 4 4 4 2 EF-hand domain EF-hand_7 PF13499.6 OQS06862.1 - 2.4e-07 31.1 2.1 0.00039 20.8 0.2 3.3 1 1 2 3 3 3 3 EF-hand domain pair EF-hand_8 PF13833.6 OQS06862.1 - 0.00029 20.6 1.8 1.3 8.9 0.1 3.3 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_4 PF12763.7 OQS06862.1 - 0.0015 18.5 0.7 0.46 10.5 0.0 2.5 2 1 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand EF-hand_5 PF13202.6 OQS06862.1 - 0.0049 16.3 0.4 0.37 10.4 0.1 2.8 2 0 0 2 2 2 1 EF hand Toprim_2 PF13155.6 OQS06862.1 - 0.042 14.3 0.0 0.12 12.8 0.0 1.7 1 0 0 1 1 1 0 Toprim-like SPARC_Ca_bdg PF10591.9 OQS06862.1 - 1.3 9.3 6.2 41 4.5 0.8 3.3 2 2 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region Chorein_N PF12624.7 OQS06863.1 - 3.6e-26 91.6 0.2 9.4e-26 90.2 0.1 1.8 2 0 0 2 2 2 1 N-terminal region of Chorein or VPS13 VPS13 PF16908.5 OQS06863.1 - 3.1e-23 82.8 0.1 5.5e-23 82.0 0.1 1.4 1 0 0 1 1 1 1 Vacuolar sorting-associated protein 13, N-terminal DUF2014 PF09427.10 OQS06863.1 - 0.12 11.7 0.5 0.28 10.5 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF2014) Mcp5_PH PF12814.7 OQS06864.1 - 1.2e-05 25.4 0.0 3.1e-05 24.1 0.0 1.7 1 0 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology p25-alpha PF05517.12 OQS06864.1 - 4.6e-05 23.6 0.0 0.00019 21.6 0.0 1.9 2 0 0 2 2 2 1 p25-alpha PH PF00169.29 OQS06864.1 - 8.3e-05 23.1 0.8 0.001 19.5 0.2 2.7 3 0 0 3 3 3 1 PH domain PH_2 PF08458.10 OQS06864.1 - 0.0011 19.2 0.1 0.0033 17.8 0.1 1.7 2 0 0 2 2 2 1 Plant pleckstrin homology-like region PH_12 PF16457.5 OQS06864.1 - 0.2 12.2 0.6 1.1 9.8 0.2 2.3 2 1 0 2 2 2 0 Pleckstrin homology domain FYVE PF01363.21 OQS06865.1 - 9.4e-13 48.1 15.9 4.9e-12 45.8 15.9 2.3 1 1 0 1 1 1 1 FYVE zinc finger DEP PF00610.21 OQS06865.1 - 0.00036 20.5 0.1 0.00081 19.4 0.1 1.5 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Zn-ribbon_8 PF09723.10 OQS06865.1 - 1.7 8.8 13.1 4 7.6 2.7 3.3 2 1 1 3 3 3 0 Zinc ribbon domain Peptidase_M18 PF02127.15 OQS06866.1 - 1.5e-158 528.2 0.0 1.7e-158 528.0 0.0 1.0 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Peptidase_M42 PF05343.14 OQS06866.1 - 0.00041 19.5 0.0 0.0054 15.8 0.0 2.3 3 0 0 3 3 3 1 M42 glutamyl aminopeptidase SMC_N PF02463.19 OQS06867.1 - 3.4e-27 95.3 0.0 1.2e-26 93.5 0.0 1.9 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 OQS06867.1 - 7.9e-09 36.3 74.4 4.3e-08 33.9 41.8 5.3 2 2 0 2 2 2 1 AAA domain AAA_15 PF13175.6 OQS06867.1 - 1.8e-05 24.7 8.4 1.8e-05 24.7 8.4 2.7 2 1 0 2 2 2 1 AAA ATPase domain AAA_21 PF13304.6 OQS06867.1 - 0.00055 19.8 0.7 0.12 12.1 0.0 2.9 2 1 0 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 OQS06867.1 - 0.0096 15.6 0.0 0.022 14.5 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF4472 PF14739.6 OQS06867.1 - 0.015 16.0 5.8 0.015 16.0 5.8 6.7 3 2 4 7 7 7 0 Domain of unknown function (DUF4472) DUF2935 PF11155.8 OQS06867.1 - 0.37 11.1 19.0 3.8 7.8 6.1 4.9 4 2 0 4 4 4 0 Domain of unknown function (DUF2935) Baculo_PEP_C PF04513.12 OQS06867.1 - 0.98 9.5 24.1 2.1 8.4 2.4 4.7 3 1 1 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1664 PF07889.12 OQS06867.1 - 5.3 7.1 45.5 1.4 8.9 3.7 6.5 3 2 3 6 6 6 0 Protein of unknown function (DUF1664) AAA_13 PF13166.6 OQS06867.1 - 8.7 4.9 74.5 0.0042 15.8 12.3 5.1 3 2 2 5 5 5 0 AAA domain Radical_SAM_C PF16199.5 OQS06868.1 - 8.9e-22 76.9 0.2 1.7e-21 76.1 0.2 1.5 1 0 0 1 1 1 1 Radical_SAM C-terminal domain Radical_SAM PF04055.21 OQS06868.1 - 2.7e-16 60.4 0.4 1.2e-15 58.3 0.4 2.1 1 0 0 1 1 1 1 Radical SAM superfamily Acetyltransf_1 PF00583.25 OQS06868.1 - 5.7e-09 36.2 0.1 2.2e-08 34.3 0.0 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 OQS06868.1 - 0.0001 22.2 0.1 0.00027 20.8 0.1 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 OQS06868.1 - 0.0088 16.5 0.0 0.022 15.2 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Gram_pos_anchor PF00746.21 OQS06868.1 - 0.44 10.5 1.4 0.91 9.5 1.4 1.6 1 0 0 1 1 1 0 LPXTG cell wall anchor motif DNA_pol_B PF00136.21 OQS06869.1 - 1.2e-94 317.6 0.0 2.3e-94 316.7 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 OQS06869.1 - 3.9e-26 92.0 0.3 2.1e-11 43.5 0.0 3.6 3 1 0 3 3 3 2 DNA polymerase family B, exonuclease domain OrfB_Zn_ribbon PF07282.11 OQS06869.1 - 5.3e-07 29.5 0.1 1.2e-06 28.3 0.1 1.7 1 0 0 1 1 1 1 Putative transposase DNA-binding domain zf-C4pol PF14260.6 OQS06869.1 - 5.7e-05 23.5 3.8 0.0002 21.7 3.8 2.0 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta Inhibitor_I53 PF11714.8 OQS06869.1 - 0.71 10.1 2.4 2.5 8.4 2.4 2.0 1 0 0 1 1 1 0 Thrombin inhibitor Madanin TonB_N PF16031.5 OQS06870.1 - 0.5 10.9 7.7 0.55 10.8 6.0 1.8 2 0 0 2 2 2 0 TonB polyproline region Trypan_PARP PF05887.11 OQS06870.1 - 2.7 8.0 7.2 7.2 6.6 4.2 2.3 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) Metallophos PF00149.28 OQS06871.1 - 9.7e-21 75.2 1.4 9.7e-21 75.2 1.4 1.5 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase Metallophos_C PF14008.6 OQS06871.1 - 4e-19 69.2 0.3 1.4e-18 67.5 0.3 2.0 1 0 0 1 1 1 1 Iron/zinc purple acid phosphatase-like protein C Pur_ac_phosph_N PF16656.5 OQS06871.1 - 8.3e-05 23.1 0.2 0.076 13.6 0.0 3.0 3 0 0 3 3 3 2 Purple acid Phosphatase, N-terminal domain Metallophos_2 PF12850.7 OQS06871.1 - 0.00093 19.4 0.1 0.0034 17.6 0.1 1.9 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain 2OG-FeII_Oxy_2 PF13532.6 OQS06873.1 - 1.3e-37 129.9 0.0 1.7e-37 129.6 0.0 1.2 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Helicase_C PF00271.31 OQS06874.1 - 0.0012 19.1 0.0 0.0028 18.0 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Phage-tail_3 PF13550.6 OQS06874.1 - 0.094 12.6 0.1 0.17 11.7 0.1 1.3 1 0 0 1 1 1 0 Putative phage tail protein zf-met PF12874.7 OQS06874.1 - 1.6 9.2 5.9 18 5.9 5.9 2.5 1 1 0 1 1 1 0 Zinc-finger of C2H2 type MOZ_SAS PF01853.18 OQS06875.1 - 8.1e-67 224.3 0.2 1.1e-66 223.8 0.2 1.2 1 0 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 OQS06875.1 - 7.2e-17 60.7 2.1 1.8e-16 59.4 2.1 1.7 1 0 0 1 1 1 1 MYST family zinc finger domain Acetyltransf_7 PF13508.7 OQS06875.1 - 0.00024 21.5 0.0 0.0005 20.4 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 OQS06875.1 - 0.0048 17.1 0.0 0.0095 16.2 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family RPM2 PF08579.11 OQS06875.1 - 0.046 14.1 0.3 1.1 9.7 0.1 2.3 2 0 0 2 2 2 0 Mitochondrial ribonuclease P subunit (RPM2) WD40 PF00400.32 OQS06876.1 - 2.3e-16 59.8 6.9 0.00014 22.5 0.1 5.8 5 0 0 5 5 5 3 WD domain, G-beta repeat FHA PF00498.26 OQS06876.1 - 1.7e-15 57.1 0.1 3.6e-15 56.1 0.1 1.6 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 OQS06876.1 - 3.3e-09 36.9 0.3 7.8e-09 35.7 0.3 1.6 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain ANAPC4_WD40 PF12894.7 OQS06876.1 - 9.6e-05 22.6 0.0 1.4 9.2 0.0 4.0 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain SWIB PF02201.18 OQS06877.1 - 1e-60 201.5 4.2 1.1e-30 105.4 0.1 2.8 3 0 0 3 3 3 2 SWIB/MDM2 domain DEK_C PF08766.11 OQS06877.1 - 2.9e-15 55.9 4.7 4.6e-15 55.3 2.9 2.2 2 0 0 2 2 2 1 DEK C terminal domain eIF-3c_N PF05470.12 OQS06877.1 - 0.00013 20.4 1.2 0.00023 19.6 1.0 1.4 1 1 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 8 N-terminus YL1 PF05764.13 OQS06877.1 - 0.0025 18.0 18.2 0.048 13.8 2.5 2.3 2 0 0 2 2 2 2 YL1 nuclear protein DUF2052 PF09747.9 OQS06877.1 - 0.049 13.8 10.7 0.26 11.4 3.6 2.3 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) RR_TM4-6 PF06459.12 OQS06877.1 - 0.13 12.1 9.4 1.4 8.7 2.8 2.2 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 U3_snoRNA_assoc PF08297.11 OQS06877.1 - 0.17 12.6 12.3 2.6 8.8 2.2 2.7 2 0 0 2 2 2 0 U3 snoRNA associated V_ATPase_I PF01496.19 OQS06877.1 - 0.21 9.5 6.9 0.35 8.7 6.2 1.5 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family eIF3_subunit PF08597.10 OQS06877.1 - 0.47 10.3 23.9 0.56 10.1 6.3 2.4 2 0 0 2 2 2 0 Translation initiation factor eIF3 subunit Rxt3 PF08642.10 OQS06877.1 - 0.63 10.8 3.7 8.8 7.1 0.3 2.3 2 0 0 2 2 2 0 Histone deacetylation protein Rxt3 YABBY PF04690.13 OQS06877.1 - 0.77 10.3 6.9 11 6.6 0.3 2.3 2 0 0 2 2 2 0 YABBY protein Sporozoite_P67 PF05642.11 OQS06877.1 - 2 6.4 9.7 3.4 5.7 3.5 2.0 2 0 0 2 2 2 0 Sporozoite P67 surface antigen Peptidase_C37 PF05416.12 OQS06877.1 - 3.5 6.0 7.5 1.1 7.6 0.8 2.0 2 0 0 2 2 2 0 Southampton virus-type processing peptidase RNA_pol_Rpc4 PF05132.14 OQS06877.1 - 5.4 7.4 13.0 2.1 8.8 1.7 2.4 2 0 0 2 2 2 0 RNA polymerase III RPC4 NA37 PF04245.13 OQS06877.1 - 7 6.0 12.9 0.021 14.3 2.7 1.9 2 0 0 2 2 1 0 37-kD nucleoid-associated bacterial protein Myb_DNA-binding PF00249.31 OQS06878.1 - 1.4e-09 38.0 0.1 3.9e-09 36.6 0.1 1.8 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OQS06878.1 - 0.073 13.3 0.1 0.16 12.2 0.1 1.7 1 0 0 1 1 1 0 Myb-like DNA-binding domain DUF4672 PF15716.5 OQS06878.1 - 0.075 12.7 0.6 0.82 9.3 0.0 2.2 2 1 1 3 3 3 0 Domain of unknown function (DUF4672) Nbl1_Borealin_N PF10444.9 OQS06879.1 - 1.2e-06 28.0 3.2 1.2e-06 28.0 3.2 2.9 3 0 0 3 3 3 1 Nbl1 / Borealin N terminal Borealin PF10512.9 OQS06879.1 - 0.67 9.9 8.7 0.17 11.9 4.3 2.4 2 1 0 2 2 2 0 Cell division cycle-associated protein 8 Mt_ATP-synt_D PF05873.12 OQS06879.1 - 0.75 9.6 4.3 0.24 11.3 0.6 1.9 2 0 0 2 2 2 0 ATP synthase D chain, mitochondrial (ATP5H) DUF438 PF04282.13 OQS06879.1 - 0.94 9.5 4.4 2.2 8.3 0.3 2.7 2 1 1 3 3 3 0 Family of unknown function (DUF438) L_lactis_ph-MCP PF06673.11 OQS06879.1 - 1.6 7.7 4.6 0.29 10.1 0.6 1.6 2 0 0 2 2 2 0 Lactococcus lactis bacteriophage major capsid protein DUF4795 PF16043.5 OQS06879.1 - 2.2 7.9 11.9 2 8.0 2.4 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF4795) FliT PF05400.13 OQS06879.1 - 2.6 8.9 8.3 5.1 8.0 1.8 2.7 2 1 0 2 2 2 0 Flagellar protein FliT YtxH PF12732.7 OQS06879.1 - 5.4 7.6 7.3 1.3 9.6 1.2 2.2 2 0 0 2 2 2 0 YtxH-like protein ParA PF10609.9 OQS06880.1 - 1.3e-78 263.9 0.1 1.6e-78 263.5 0.1 1.1 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase DUF971 PF06155.12 OQS06880.1 - 1.5e-16 60.8 0.0 3.2e-16 59.7 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF971) CbiA PF01656.23 OQS06880.1 - 2.8e-11 43.6 0.0 5e-11 42.8 0.0 1.4 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 OQS06880.1 - 5.4e-10 39.5 1.1 5.2e-08 33.0 1.1 2.3 1 1 0 1 1 1 1 AAA domain FeS_assembly_P PF01883.19 OQS06880.1 - 1e-08 35.2 0.0 2.1e-08 34.2 0.0 1.6 1 0 0 1 1 1 1 Iron-sulfur cluster assembly protein MipZ PF09140.11 OQS06880.1 - 1.4e-08 34.4 0.0 1.2e-05 24.7 0.0 2.2 2 0 0 2 2 2 2 ATPase MipZ ArsA_ATPase PF02374.15 OQS06880.1 - 2e-06 27.2 0.6 0.048 12.8 0.0 2.6 2 1 0 2 2 2 2 Anion-transporting ATPase CBP_BcsQ PF06564.12 OQS06880.1 - 7.7e-05 22.3 0.1 0.002 17.6 0.1 2.3 2 0 0 2 2 2 1 Cellulose biosynthesis protein BcsQ Fer4_NifH PF00142.18 OQS06880.1 - 0.00032 20.2 0.1 0.00063 19.3 0.1 1.5 1 1 0 1 1 1 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family VirC1 PF07015.11 OQS06880.1 - 0.0055 16.0 0.0 0.014 14.7 0.0 1.7 2 0 0 2 2 2 1 VirC1 protein FadA PF09403.10 OQS06882.1 - 0.0098 16.4 1.0 0.0098 16.4 1.0 2.4 2 2 0 2 2 2 1 Adhesion protein FadA TSC22 PF01166.18 OQS06882.1 - 0.15 12.4 8.1 1 9.7 0.0 3.1 3 1 1 4 4 4 0 TSC-22/dip/bun family DUF2205 PF10224.9 OQS06882.1 - 0.85 9.7 13.9 4.7 7.3 4.1 2.8 2 1 0 2 2 2 0 Short coiled-coil protein DUF4140 PF13600.6 OQS06882.1 - 1.1 9.7 6.0 16 6.0 2.1 2.5 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) UPF0225 PF17775.1 OQS06882.1 - 1.2 10.0 5.5 0.25 12.2 1.3 1.9 2 1 0 2 2 2 0 UPF0225 domain FlxA PF14282.6 OQS06882.1 - 2.3 8.2 14.2 2.4 8.2 0.6 2.6 2 1 0 2 2 2 0 FlxA-like protein bZIP_1 PF00170.21 OQS06882.1 - 6.5 6.9 23.8 0.1 12.7 2.6 3.9 4 0 0 4 4 4 0 bZIP transcription factor DivIC PF04977.15 OQS06882.1 - 9.9 6.0 9.8 5.8 6.8 1.2 2.9 3 0 0 3 3 3 0 Septum formation initiator Pkinase PF00069.25 OQS06883.1 - 6.2e-84 281.5 0.0 8.4e-43 146.6 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OQS06883.1 - 1.2e-79 267.3 0.0 2e-42 145.2 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase C2 PF00168.30 OQS06883.1 - 9.1e-10 38.8 0.0 1.7e-09 37.9 0.0 1.5 1 0 0 1 1 1 1 C2 domain Pkinase_fungal PF17667.1 OQS06883.1 - 3.6e-09 35.9 0.0 0.00086 18.2 0.0 2.2 2 0 0 2 2 2 2 Fungal protein kinase Kdo PF06293.14 OQS06883.1 - 1.2e-07 31.3 0.5 0.007 15.7 0.0 3.1 3 0 0 3 3 3 2 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OQS06883.1 - 9.3e-05 22.5 0.2 0.04 13.8 0.1 2.8 2 1 0 2 2 2 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 OQS06883.1 - 0.0002 20.4 0.3 0.23 10.4 0.0 3.2 3 1 0 3 3 3 1 Haspin like kinase domain Kinase-like PF14531.6 OQS06883.1 - 0.00083 18.8 0.0 0.98 8.7 0.0 2.4 2 0 0 2 2 2 2 Kinase-like FTA2 PF13095.6 OQS06883.1 - 0.013 15.1 0.1 4.3 6.9 0.0 3.4 4 0 0 4 4 4 0 Kinetochore Sim4 complex subunit FTA2 ZapB PF06005.12 OQS06883.1 - 0.016 15.6 1.3 0.035 14.6 1.3 1.5 1 0 0 1 1 1 0 Cell division protein ZapB Choline_kinase PF01633.20 OQS06883.1 - 0.034 13.7 0.3 13 5.3 0.0 3.1 3 0 0 3 3 3 0 Choline/ethanolamine kinase RIO1 PF01163.22 OQS06883.1 - 0.095 12.3 0.1 7.6 6.1 0.0 3.0 3 0 0 3 3 3 0 RIO1 family IFP_35_N PF07334.13 OQS06883.1 - 0.15 12.2 3.3 0.32 11.1 3.3 1.5 1 0 0 1 1 1 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus Pox_ser-thr_kin PF05445.11 OQS06883.1 - 0.2 10.6 0.1 2.1 7.2 0.0 2.0 2 0 0 2 2 2 0 Poxvirus serine/threonine protein kinase DUF1640 PF07798.11 OQS06883.1 - 0.31 11.1 2.0 0.64 10.1 2.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) TolA_bind_tri PF16331.5 OQS06883.1 - 0.59 10.3 5.5 1.2 9.2 5.5 1.5 1 0 0 1 1 1 0 TolA binding protein trimerisation HALZ PF02183.18 OQS06883.1 - 1.2 9.4 5.1 2.9 8.2 5.1 1.6 1 0 0 1 1 1 0 Homeobox associated leucine zipper Colicin_immun PF09204.10 OQS06884.1 - 0.14 12.7 1.6 7 7.2 0.0 2.9 2 0 0 2 2 2 0 Bacterial self-protective colicin-like immunity MCC-bdg_PDZ PF10506.9 OQS06884.1 - 0.14 12.2 1.8 0.33 11.0 1.8 1.6 1 0 0 1 1 1 0 PDZ domain of MCC-2 bdg protein for Usher syndrome bZIP_2 PF07716.15 OQS06884.1 - 0.18 11.9 7.0 0.68 10.1 7.0 2.0 1 0 0 1 1 1 0 Basic region leucine zipper HPIP PF15226.6 OQS06884.1 - 2 8.9 5.3 1.9 8.9 1.3 2.6 3 0 0 3 3 3 0 HCF-1 beta-propeller-interacting protein family His_biosynth PF00977.21 OQS06885.1 - 1.4e-45 155.6 0.1 8.5e-45 153.0 0.1 2.3 1 1 0 1 1 1 1 Histidine biosynthesis protein GATase PF00117.28 OQS06885.1 - 3.6e-22 79.0 0.0 5.6e-22 78.4 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I SNO PF01174.19 OQS06885.1 - 2.4e-07 30.8 0.0 1.1e-06 28.6 0.0 2.0 1 1 0 1 1 1 1 SNO glutamine amidotransferase family GATase_3 PF07685.14 OQS06885.1 - 7.8e-07 28.9 0.0 1.6e-06 27.9 0.0 1.5 1 1 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain Peptidase_C26 PF07722.13 OQS06885.1 - 0.00047 20.0 0.1 0.003 17.4 0.1 2.1 1 1 0 1 1 1 1 Peptidase C26 ERO1 PF04137.15 OQS06886.1 - 3.7e-117 391.5 0.8 5.3e-117 391.0 0.8 1.2 1 0 0 1 1 1 1 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) DUF3185 PF11381.8 OQS06886.1 - 0.048 13.7 0.1 0.093 12.7 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3185) WD40 PF00400.32 OQS06887.1 - 1.1e-69 228.6 14.9 2e-09 37.9 0.0 8.1 8 0 0 8 8 8 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OQS06887.1 - 1.8e-20 73.0 1.8 6e-05 23.3 0.0 7.0 1 1 7 8 8 8 6 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 OQS06887.1 - 1e-10 41.4 6.4 0.00025 20.5 0.6 5.4 4 2 0 5 5 5 4 WD40-like domain Ge1_WD40 PF16529.5 OQS06887.1 - 1.4e-09 37.4 4.8 0.02 13.9 0.0 5.0 1 1 3 4 4 4 4 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 OQS06887.1 - 3.8e-09 36.7 6.0 0.0042 17.0 0.0 3.4 1 1 4 5 5 5 5 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 OQS06887.1 - 6.8e-07 28.3 7.5 0.39 9.3 0.0 5.3 2 2 4 6 6 6 3 Nucleoporin Nup120/160 DUF5570 PF17731.1 OQS06887.1 - 4.2e-05 23.6 4.3 0.094 12.8 0.0 4.7 1 1 4 5 5 5 1 Family of unknown function (DUF5570) WD40_3 PF15911.5 OQS06887.1 - 0.0047 16.9 0.0 9.4 6.3 0.0 4.1 4 0 0 4 4 4 1 WD domain, G-beta repeat Frtz PF11768.8 OQS06887.1 - 0.014 13.8 0.1 18 3.5 0.0 4.3 2 1 1 5 5 5 0 WD repeat-containing and planar cell polarity effector protein Fritz PKD PF00801.20 OQS06887.1 - 0.12 12.2 0.9 55 3.7 0.0 3.4 3 0 0 3 3 3 0 PKD domain ParBc PF02195.18 OQS06889.1 - 3e-09 37.0 0.0 0.0034 17.7 0.0 2.6 2 0 0 2 2 2 2 ParB-like nuclease domain Cas6_N PF17952.1 OQS06889.1 - 0.09 13.1 0.0 0.2 11.9 0.0 1.5 1 0 0 1 1 1 0 Cas6 N-terminal domain CRT-like PF08627.10 OQS06890.1 - 4.1e-58 196.9 11.0 4.9e-58 196.7 11.0 1.1 1 0 0 1 1 1 1 CRT-like, chloroquine-resistance transporter-like SLC35F PF06027.12 OQS06890.1 - 4.1e-05 23.2 0.9 4.1e-05 23.2 0.9 2.3 2 1 0 2 2 2 1 Solute carrier family 35 zf-RING_2 PF13639.6 OQS06891.1 - 5.3e-12 45.9 6.0 5.3e-12 45.9 6.0 3.3 4 0 0 4 4 3 1 Ring finger domain zf-RING_UBOX PF13445.6 OQS06891.1 - 4.1e-08 33.1 2.7 3.2e-07 30.3 2.9 2.5 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 OQS06891.1 - 2.4e-07 30.5 5.5 2.4e-07 30.5 5.5 3.5 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 OQS06891.1 - 2.8e-07 30.7 6.2 2.8e-07 30.7 6.2 3.2 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-RING_11 PF17123.5 OQS06891.1 - 1.4e-06 28.0 1.7 1.4e-06 28.0 1.7 2.4 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4_3 PF13920.6 OQS06891.1 - 3.5e-06 26.8 3.2 3.5e-06 26.8 3.2 2.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 OQS06891.1 - 5.9e-06 26.1 6.8 5.9e-06 26.1 6.8 2.5 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OQS06891.1 - 2.2e-05 24.3 3.7 2.2e-05 24.3 3.7 2.7 2 0 0 2 2 2 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 OQS06891.1 - 0.00026 21.0 1.7 0.00086 19.3 1.7 2.0 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-Nse PF11789.8 OQS06891.1 - 0.00095 18.9 1.1 0.0034 17.2 1.1 1.9 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit Prok-RING_4 PF14447.6 OQS06891.1 - 0.0011 18.7 4.8 0.0036 17.1 4.8 2.0 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 Zn_ribbon_17 PF17120.5 OQS06891.1 - 0.026 14.1 17.9 0.023 14.3 3.6 2.9 3 0 0 3 3 2 0 Zinc-ribbon, C4HC2 type RINGv PF12906.7 OQS06891.1 - 0.12 12.5 8.9 0.57 10.3 8.9 2.3 1 0 0 1 1 1 0 RING-variant domain zf-C3H2C3 PF17122.5 OQS06891.1 - 0.49 10.5 7.0 0.24 11.4 1.9 2.8 2 0 0 2 2 2 0 Zinc-finger CRT-like PF08627.10 OQS06892.1 - 2.3e-62 210.9 13.5 3e-62 210.5 13.5 1.1 1 0 0 1 1 1 1 CRT-like, chloroquine-resistance transporter-like SLC35F PF06027.12 OQS06892.1 - 0.0023 17.5 7.6 0.15 11.5 0.3 2.2 2 0 0 2 2 2 2 Solute carrier family 35 HSF_DNA-bind PF00447.17 OQS06893.1 - 8.7e-63 209.0 15.3 4.5e-25 88.1 0.4 3.6 3 0 0 3 3 3 3 HSF-type DNA-binding Flu_B_NS1 PF02942.14 OQS06893.1 - 0.003 16.7 2.6 3.2 6.8 0.1 3.1 3 0 0 3 3 3 3 Influenza B non-structural protein (NS1) Melittin PF01372.17 OQS06893.1 - 0.45 10.6 1.0 25 5.1 0.0 3.2 3 0 0 3 3 3 0 Melittin DUF4833 PF16117.5 OQS06894.1 - 5.8e-37 126.8 0.0 6.9e-37 126.5 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4833) Trypsin_2 PF13365.6 OQS06895.1 - 5.7e-73 244.8 10.7 1.2e-19 71.7 0.0 4.6 4 0 0 4 4 4 4 Trypsin-like peptidase domain Ricin_B_lectin PF00652.22 OQS06895.1 - 7.1e-37 126.5 62.1 3.8e-12 46.5 3.9 6.5 8 0 0 8 8 8 4 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.6 OQS06895.1 - 8e-15 55.3 35.1 0.00048 20.8 1.8 8.0 4 3 2 7 7 7 5 Ricin-type beta-trefoil lectin domain-like Peptidase_S46 PF10459.9 OQS06895.1 - 2.7e-12 46.2 26.0 0.077 11.6 0.0 8.2 8 0 0 8 8 8 6 Peptidase S46 Peptidase_C4 PF00863.19 OQS06895.1 - 0.0007 19.0 5.5 3.1 7.0 0.1 4.2 4 0 0 4 4 4 3 Peptidase family C4 Peptidase_S7 PF00949.21 OQS06895.1 - 0.0012 18.7 9.3 12 5.8 0.2 4.8 4 0 0 4 4 4 2 Peptidase S7, Flavivirus NS3 serine protease Fascin PF06268.13 OQS06895.1 - 0.0016 18.6 0.7 0.014 15.6 0.1 2.8 2 0 0 2 2 2 1 Fascin domain EF-hand_9 PF14658.6 OQS06895.1 - 0.073 13.4 0.0 0.79 10.1 0.0 2.7 3 0 0 3 3 3 0 EF-hand domain zf-RING_11 PF17123.5 OQS06895.1 - 0.17 11.7 1.2 14 5.6 0.1 3.1 2 0 0 2 2 2 0 RING-like zinc finger Flu_M1 PF00598.19 OQS06895.1 - 1.9 8.0 5.9 5.2 6.5 0.1 3.8 4 0 0 4 4 4 0 Influenza Matrix protein (M1) NAT PF04768.13 OQS06895.1 - 2.3 7.8 4.7 0.32 10.6 0.2 1.9 2 0 0 2 2 2 0 NAT, N-acetyltransferase, of N-acetylglutamate synthase CRAL_TRIO PF00650.20 OQS06896.1 - 5.6e-18 65.2 0.0 8.1e-18 64.6 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain WD40 PF00400.32 OQS06897.1 - 7.9e-11 42.3 5.0 0.0018 19.1 0.1 3.7 4 0 0 4 4 4 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OQS06897.1 - 0.039 14.2 0.1 0.089 13.1 0.1 1.7 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 4 WD40 domain OCD_Mu_crystall PF02423.15 OQS06897.1 - 0.23 10.4 0.0 0.27 10.1 0.0 1.2 1 0 0 1 1 1 0 Ornithine cyclodeaminase/mu-crystallin family Pkinase_Tyr PF07714.17 OQS06898.1 - 3.7e-57 193.6 0.3 2e-56 191.1 0.0 2.2 3 0 0 3 3 3 1 Protein tyrosine kinase Pkinase PF00069.25 OQS06898.1 - 4.2e-48 164.0 0.0 1e-47 162.7 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain WBP-1 PF11669.8 OQS06898.1 - 0.066 13.8 0.1 0.17 12.5 0.1 1.7 1 0 0 1 1 1 0 WW domain-binding protein 1 DUF3139 PF11337.8 OQS06898.1 - 5.4 7.7 9.4 1.4 9.6 0.2 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3139) WD40 PF00400.32 OQS06899.1 - 4e-35 119.2 19.5 1.5e-07 32.0 0.1 8.0 8 0 0 8 8 8 6 WD domain, G-beta repeat Bromodomain PF00439.25 OQS06899.1 - 5.4e-31 106.5 0.2 1.2e-15 57.3 0.0 2.6 2 0 0 2 2 2 2 Bromodomain zf-HC5HC2H PF13771.6 OQS06899.1 - 2.8e-09 37.1 6.6 6.7e-09 35.9 6.6 1.7 1 0 0 1 1 1 1 PHD-like zinc-binding domain ANAPC4_WD40 PF12894.7 OQS06899.1 - 1.4e-07 31.7 0.0 3.1 8.2 0.0 5.8 2 2 3 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain zf-HC5HC2H_2 PF13832.6 OQS06899.1 - 1.3e-06 28.6 4.7 3.2e-06 27.3 4.7 1.6 1 0 0 1 1 1 1 PHD-zinc-finger like domain Ge1_WD40 PF16529.5 OQS06899.1 - 1.5e-05 24.2 0.1 0.11 11.5 0.0 4.2 4 1 2 6 6 6 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 OQS06899.1 - 0.0045 15.7 2.3 1.2 7.7 0.1 3.8 2 1 2 4 4 4 1 Nucleoporin Nup120/160 WD40_like PF17005.5 OQS06899.1 - 0.018 14.4 0.2 2.8 7.2 0.0 2.7 3 0 0 3 3 3 0 WD40-like domain C1_2 PF03107.16 OQS06899.1 - 0.11 12.8 4.4 0.14 12.5 2.4 2.3 2 0 0 2 2 2 0 C1 domain zf-RING-like PF08746.11 OQS06899.1 - 2.1 8.7 5.8 7.3 7.0 5.8 1.9 1 0 0 1 1 1 0 RING-like domain Catalase PF00199.19 OQS06900.1 - 6.1e-188 624.7 0.1 7.3e-188 624.4 0.1 1.0 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.12 OQS06900.1 - 3.1e-22 78.6 0.5 1.2e-21 76.6 0.2 2.2 2 0 0 2 2 2 1 Catalase-related immune-responsive SNRNP27 PF08648.12 OQS06901.1 - 2e-17 63.0 1.4 2e-17 63.0 1.4 2.2 2 0 0 2 2 2 1 U4/U6.U5 small nuclear ribonucleoproteins DUF3638 PF12340.8 OQS06902.1 - 8.2e-29 100.5 0.1 4e-28 98.3 0.1 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF3638) Thioredoxin_8 PF13905.6 OQS06902.1 - 1.8e-16 60.2 0.0 1.8e-15 57.0 0.0 2.8 3 0 0 3 3 3 1 Thioredoxin-like DUF3645 PF12359.8 OQS06902.1 - 2.5e-15 55.5 0.1 6e-15 54.3 0.1 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3645) UBA PF00627.31 OQS06902.1 - 0.0002 21.2 0.0 0.00065 19.5 0.0 1.9 1 0 0 1 1 1 1 UBA/TS-N domain EF-hand_1 PF00036.32 OQS06902.1 - 0.0057 16.1 0.0 0.021 14.3 0.0 2.0 1 0 0 1 1 1 1 EF hand zf-RanBP PF00641.18 OQS06902.1 - 0.011 15.0 36.2 0.0032 16.8 2.6 4.8 4 0 0 4 4 4 0 Zn-finger in Ran binding protein and others Thioredoxin_2 PF13098.6 OQS06902.1 - 0.014 15.8 0.0 0.046 14.2 0.0 1.9 1 0 0 1 1 1 0 Thioredoxin-like domain EF-hand_7 PF13499.6 OQS06902.1 - 0.032 14.7 0.1 0.17 12.4 0.0 2.3 2 0 0 2 2 2 0 EF-hand domain pair EF-hand_6 PF13405.6 OQS06902.1 - 0.055 13.4 0.1 0.31 11.1 0.1 2.3 2 0 0 2 2 2 0 EF-hand domain zf-Sec23_Sec24 PF04810.15 OQS06902.1 - 0.17 12.0 8.2 10 6.3 1.1 4.2 3 0 0 3 3 3 0 Sec23/Sec24 zinc finger IF4E PF01652.18 OQS06904.1 - 1.4e-38 132.2 0.9 1.7e-38 131.9 0.9 1.0 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E DUF3668 PF12416.8 OQS06907.1 - 4.7e-18 65.8 0.2 4.7e-18 65.8 0.2 2.3 2 0 0 2 2 2 1 Cep120 protein AAA_13 PF13166.6 OQS06907.1 - 8.5 4.9 35.1 0.24 10.0 27.7 1.8 1 1 1 2 2 2 0 AAA domain PAN_1 PF00024.26 OQS06908.1 - 1.3e-09 37.9 8.9 2e-07 30.9 1.5 3.4 3 1 1 4 4 4 2 PAN domain PAN_4 PF14295.6 OQS06908.1 - 6.3e-07 29.2 7.1 0.00013 21.8 0.6 3.8 4 0 0 4 4 4 2 PAN domain Lustrin_cystein PF14625.6 OQS06908.1 - 0.0076 16.6 1.8 0.0076 16.6 1.8 2.7 3 0 0 3 3 3 1 Lustrin, cysteine-rich repeated domain PAN_3 PF08277.12 OQS06908.1 - 0.06 13.2 0.7 0.06 13.2 0.7 3.6 5 0 0 5 5 5 0 PAN-like domain zf-like PF04071.12 OQS06908.1 - 0.13 12.2 0.1 0.13 12.2 0.1 3.3 2 2 1 4 4 4 0 Cysteine-rich small domain YrhK PF14145.6 OQS06909.1 - 1.8e-24 85.3 28.8 2.2e-09 37.0 3.0 3.2 3 0 0 3 3 3 3 YrhK-like protein DUF726 PF05277.12 OQS06910.1 - 8e-91 304.5 3.0 1.1e-63 215.2 0.0 2.2 1 1 1 2 2 2 2 Protein of unknown function (DUF726) FWWh PF14922.6 OQS06910.1 - 1.1e-31 109.7 2.5 1.4e-31 109.4 0.5 2.3 2 0 0 2 2 2 1 Protein of unknown function B2-adapt-app_C PF09066.10 OQS06910.1 - 2.2e-06 27.7 0.0 5.9e-06 26.3 0.0 1.7 1 0 0 1 1 1 1 Beta2-adaptin appendage, C-terminal sub-domain CLN3 PF02487.17 OQS06910.1 - 0.0001 21.5 0.1 0.00031 19.9 0.1 1.8 1 0 0 1 1 1 1 CLN3 protein CCDC106 PF15794.5 OQS06910.1 - 0.0039 16.9 4.0 0.014 15.1 4.0 1.9 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 106 DUF4614 PF15391.6 OQS06910.1 - 0.0059 16.6 7.6 0.022 14.8 7.6 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF4614) CDC45 PF02724.14 OQS06910.1 - 0.096 11.0 9.8 0.1 10.8 8.5 1.6 2 0 0 2 2 2 0 CDC45-like protein Zip PF02535.22 OQS06910.1 - 1.2 8.2 7.5 0.28 10.4 0.1 2.8 3 0 0 3 3 3 0 ZIP Zinc transporter PPL5 PF18168.1 OQS06910.1 - 6.6 5.9 6.9 16 4.7 6.9 1.6 1 0 0 1 1 1 0 Prim-pol family 5 Ctr PF04145.15 OQS06910.1 - 7.4 7.2 8.3 0.83 10.3 0.0 3.4 2 1 0 2 2 2 0 Ctr copper transporter family RabGAP-TBC PF00566.18 OQS06911.1 - 5.2e-10 39.3 0.6 5.2e-10 39.3 0.6 2.0 2 0 0 2 2 2 1 Rab-GTPase-TBC domain WD40 PF00400.32 OQS06911.1 - 8.8e-09 35.9 0.1 10 7.2 0.0 6.0 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OQS06911.1 - 0.0013 19.0 0.0 0.54 10.6 0.0 3.9 3 1 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain DUF2415 PF10313.9 OQS06911.1 - 0.033 14.1 0.1 2.4 8.1 0.0 2.6 2 0 0 2 2 2 0 Uncharacterised protein domain (DUF2415) DEAD PF00270.29 OQS06912.1 - 7.6e-47 159.3 0.0 1.9e-46 158.1 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OQS06912.1 - 4.2e-25 88.2 0.1 6.8e-24 84.4 0.0 2.7 3 0 0 3 3 3 1 Helicase conserved C-terminal domain GUCT PF08152.12 OQS06912.1 - 7e-21 74.3 0.0 1.8e-20 73.0 0.0 1.8 1 0 0 1 1 1 1 GUCT (NUC152) domain ResIII PF04851.15 OQS06912.1 - 2.6e-09 37.3 0.9 7.5e-09 35.8 0.0 2.1 1 1 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_30 PF13604.6 OQS06912.1 - 0.0021 17.8 0.4 0.0096 15.7 0.0 2.2 2 1 0 2 2 2 1 AAA domain CMS1 PF14617.6 OQS06912.1 - 0.0041 16.5 8.4 0.091 12.1 0.0 2.4 2 0 0 2 2 2 1 U3-containing 90S pre-ribosomal complex subunit Mating_C PF12737.7 OQS06912.1 - 0.077 12.2 3.8 0.13 11.5 3.8 1.3 1 0 0 1 1 1 0 C-terminal domain of homeodomain 1 AAA_19 PF13245.6 OQS06912.1 - 0.14 12.5 1.0 0.47 10.8 0.1 2.3 2 1 0 2 2 2 0 AAA domain SR-25 PF10500.9 OQS06912.1 - 0.31 10.6 12.4 0.48 10.0 12.4 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein ATG11 PF10377.9 OQS06912.1 - 0.32 11.1 3.9 6.3 6.9 0.0 2.4 2 0 0 2 2 2 0 Autophagy-related protein 11 DUF3987 PF13148.6 OQS06912.1 - 0.4 9.6 5.3 0.82 8.6 5.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) SnoaL_2 PF12680.7 OQS06913.1 - 4.8e-11 43.2 0.0 5.8e-11 42.9 0.0 1.1 1 0 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.6 OQS06913.1 - 7e-05 23.2 0.0 8.2e-05 23.0 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) SnoaL_3 PF13474.6 OQS06913.1 - 0.012 15.9 0.0 0.018 15.3 0.0 1.3 1 1 0 1 1 1 0 SnoaL-like domain PH_14 PF17787.1 OQS06913.1 - 0.029 14.2 0.0 0.036 13.9 0.0 1.2 1 0 0 1 1 1 0 PH domain SnoaL PF07366.12 OQS06913.1 - 0.05 13.4 0.0 0.064 13.1 0.0 1.2 1 0 0 1 1 1 0 SnoaL-like polyketide cyclase Complex1_51K PF01512.17 OQS06914.1 - 2.2e-47 160.7 0.0 4e-47 159.9 0.0 1.4 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase 51 Kd subunit NADH_4Fe-4S PF10589.9 OQS06914.1 - 1.8e-28 98.4 0.1 3.3e-28 97.6 0.1 1.5 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region SLBB PF10531.9 OQS06914.1 - 4.8e-09 36.0 0.0 1e-08 34.9 0.0 1.6 1 0 0 1 1 1 1 SLBB domain Exonuc_VII_S PF02609.16 OQS06914.1 - 0.76 9.9 1.8 1.9 8.6 0.4 2.4 2 1 1 3 3 3 0 Exonuclease VII small subunit Peptidase_C1 PF00112.23 OQS06915.1 - 1.2e-42 146.5 2.5 1.6e-42 146.1 2.5 1.2 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.15 OQS06915.1 - 0.038 12.8 0.7 0.065 12.0 0.7 1.3 1 0 0 1 1 1 0 Peptidase C1-like family Coa1 PF08695.10 OQS06916.1 - 0.042 13.6 0.2 0.29 10.9 0.0 2.1 1 1 1 2 2 2 0 Cytochrome oxidase complex assembly protein 1 FA_desaturase PF00487.24 OQS06916.1 - 0.11 12.3 2.2 1.9 8.3 0.1 2.1 2 0 0 2 2 2 0 Fatty acid desaturase DUF3054 PF11255.8 OQS06916.1 - 0.11 13.0 3.8 0.17 12.4 0.3 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF3054) Na_H_antiporter PF03553.14 OQS06917.1 - 0.0011 18.3 0.7 0.41 9.8 0.1 2.2 2 0 0 2 2 2 2 Na+/H+ antiporter family DUF3392 PF11872.8 OQS06917.1 - 7.3 6.9 8.2 0.48 10.7 0.6 2.6 4 0 0 4 4 4 0 Protein of unknown function (DUF3392) UQ_con PF00179.26 OQS06918.1 - 4.2e-33 114.0 0.0 5.7e-33 113.5 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 OQS06918.1 - 0.012 15.3 0.0 0.019 14.6 0.0 1.4 1 0 0 1 1 1 0 Prokaryotic E2 family B Nup54_57_C PF18570.1 OQS06919.1 - 0.00089 18.8 5.9 0.0084 15.7 1.7 3.5 3 0 0 3 3 3 1 NUP57/Nup54 C-terminal domain DUF4140 PF13600.6 OQS06919.1 - 0.0034 17.8 2.6 0.0034 17.8 2.6 8.7 3 1 3 6 6 6 1 N-terminal domain of unknown function (DUF4140) TACC_C PF05010.14 OQS06919.1 - 0.0076 16.1 12.9 0.0076 16.1 12.9 6.6 3 2 3 6 6 6 1 Transforming acidic coiled-coil-containing protein (TACC), C-terminal Herpes_UL51 PF04540.13 OQS06919.1 - 0.1 12.3 3.4 0.34 10.6 0.1 2.9 2 0 0 2 2 2 0 Herpesvirus UL51 protein Erythro-docking PF09277.11 OQS06919.1 - 0.63 10.0 2.4 45 4.0 0.2 3.6 2 1 1 3 3 3 0 Erythronolide synthase, docking Synaptobrevin PF00957.21 OQS06919.1 - 0.81 9.5 7.8 0.076 12.8 0.9 3.1 2 1 0 2 2 2 0 Synaptobrevin Fez1 PF06818.15 OQS06919.1 - 1.9 8.9 72.0 3.6 8.0 15.7 5.4 1 1 3 4 4 4 0 Fez1 PNRC PF15365.6 OQS06919.1 - 1.9 8.4 4.9 4.2 7.3 4.9 1.5 1 0 0 1 1 1 0 Proline-rich nuclear receptor coactivator motif PKcGMP_CC PF16808.5 OQS06919.1 - 5.5 6.9 27.4 0.4 10.6 0.2 6.9 6 1 1 7 7 7 0 Coiled-coil N-terminus of cGMP-dependent protein kinase MAPEG PF01124.18 OQS06920.1 - 0.065 13.1 8.9 0.66 9.9 8.9 2.4 1 1 0 1 1 1 0 MAPEG family DUF21 PF01595.20 OQS06920.1 - 0.12 12.1 0.0 4.3 7.0 0.0 2.2 2 0 0 2 2 2 0 Cyclin M transmembrane N-terminal domain CH PF00307.31 OQS06921.1 - 3.5e-73 242.8 3.2 2.3e-19 69.6 0.0 4.3 4 0 0 4 4 4 4 Calponin homology (CH) domain EF-hand_7 PF13499.6 OQS06921.1 - 1.7e-13 50.8 0.3 6.8e-13 48.9 0.1 2.1 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.32 OQS06921.1 - 1.3e-12 46.3 0.1 3.4e-05 23.1 0.0 2.8 2 0 0 2 2 2 2 EF hand CAMSAP_CH PF11971.8 OQS06921.1 - 5.8e-11 42.1 1.4 1.1e-05 25.2 0.0 4.4 5 0 0 5 5 5 2 CAMSAP CH domain EF-hand_5 PF13202.6 OQS06921.1 - 5.8e-10 38.2 0.8 0.00017 20.9 0.1 2.6 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 OQS06921.1 - 1.8e-09 36.7 0.4 2.9e-05 23.7 0.1 2.9 2 0 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.6 OQS06921.1 - 1.6e-07 31.1 0.2 5.5e-05 22.9 0.1 3.8 3 1 1 4 4 4 2 EF-hand domain pair SPARC_Ca_bdg PF10591.9 OQS06921.1 - 0.003 17.8 0.0 0.0071 16.7 0.0 1.6 1 0 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_9 PF14658.6 OQS06921.1 - 0.0076 16.5 0.1 0.017 15.4 0.1 1.6 1 0 0 1 1 1 1 EF-hand domain CH_2 PF06294.11 OQS06921.1 - 0.071 13.2 0.2 6.6 6.9 0.0 3.2 3 0 0 3 3 3 0 CH-like domain in sperm protein Prenylcys_lyase PF07156.14 OQS06922.1 - 7.2e-99 331.3 1.0 1.1e-84 284.6 0.0 2.1 2 0 0 2 2 2 2 Prenylcysteine lyase Amino_oxidase PF01593.24 OQS06922.1 - 1.3e-29 103.8 0.0 2.6e-23 83.0 0.0 2.2 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase Pyr_redox_3 PF13738.6 OQS06922.1 - 1.4e-07 31.1 0.2 0.0082 15.4 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OQS06922.1 - 4.4e-06 26.8 0.0 9.5e-06 25.8 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 OQS06922.1 - 0.0099 15.1 0.0 1.4 8.1 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 OQS06922.1 - 0.013 15.5 0.1 7.6 6.5 0.0 2.6 3 0 0 3 3 3 0 FAD-NAD(P)-binding CarbopepD_reg_2 PF13715.6 OQS06922.1 - 0.027 14.5 0.6 1.5 8.9 0.0 2.6 2 0 0 2 2 2 0 CarboxypepD_reg-like domain CID_GANP PF16766.5 OQS06923.1 - 0.033 14.4 0.1 38 4.6 0.0 3.1 3 0 0 3 3 3 0 Binding region of GANP to ENY2 FRG1 PF06229.12 OQS06923.1 - 0.092 12.5 0.0 0.79 9.4 0.0 2.3 1 1 1 2 2 2 0 FRG1-like domain YwqJ-deaminase PF14431.6 OQS06923.1 - 0.13 12.5 1.7 62 3.8 0.0 3.1 3 0 0 3 3 3 0 YwqJ-like deaminase DEAD PF00270.29 OQS06924.1 - 7.7e-37 126.7 0.4 1.2e-35 122.8 0.3 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OQS06924.1 - 2.6e-22 79.3 0.1 3.3e-21 75.7 0.0 2.6 3 0 0 3 3 3 1 Helicase conserved C-terminal domain zf-HIT PF04438.16 OQS06924.1 - 3.9e-06 26.6 1.0 6.7e-06 25.9 1.0 1.4 1 0 0 1 1 1 1 HIT zinc finger ResIII PF04851.15 OQS06924.1 - 0.00027 21.0 0.1 0.0011 19.0 0.0 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit T2SSE PF00437.20 OQS06924.1 - 0.027 13.6 0.0 0.066 12.3 0.0 1.6 1 0 0 1 1 1 0 Type II/IV secretion system protein Toprim_C_rpt PF13368.6 OQS06924.1 - 0.093 12.7 0.0 0.22 11.6 0.0 1.6 1 0 0 1 1 1 0 Topoisomerase C-terminal repeat ACDC PF14733.6 OQS06924.1 - 0.15 12.4 1.4 0.34 11.3 0.2 2.3 2 1 0 2 2 2 0 AP2-coincident C-terminal DUF2726 PF10881.8 OQS06924.1 - 0.26 11.2 1.5 12 5.8 0.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2726) Pep3_Vps18 PF05131.14 OQS06925.1 - 0.17 11.7 1.8 8.1 6.2 0.1 3.3 3 0 0 3 3 3 0 Pep3/Vps18/deep orange family CENP-L PF13092.6 OQS06926.1 - 0.00061 20.0 0.0 0.00089 19.5 0.0 1.2 1 0 0 1 1 1 1 Kinetochore complex Sim4 subunit Fta1 FPL PF09758.9 OQS06927.1 - 0.047 13.7 1.0 0.11 12.5 1.0 1.7 1 1 0 1 1 1 0 Uncharacterised conserved protein JAB PF01398.21 OQS06928.1 - 1.6e-17 63.5 0.0 2.6e-17 62.9 0.0 1.3 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease CSN5_C PF18323.1 OQS06928.1 - 1.2e-05 26.2 0.1 2.4e-05 25.1 0.1 1.6 1 0 0 1 1 1 1 Cop9 signalosome subunit 5 C-terminal domain Prok-JAB PF14464.6 OQS06928.1 - 0.0098 15.7 0.0 0.018 14.8 0.0 1.6 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain DUF4189 PF13827.6 OQS06928.1 - 0.11 13.0 0.5 0.25 11.9 0.5 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4189) DHHA2 PF02833.14 OQS06929.1 - 0.11 12.6 0.0 0.22 11.7 0.0 1.5 1 0 0 1 1 1 0 DHHA2 domain DUF3752 PF12572.8 OQS06930.1 - 6e-11 43.1 8.6 6e-11 43.1 8.6 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF3752) HEAT PF02985.22 OQS06930.1 - 2.2e-05 24.3 9.5 0.0011 19.0 0.0 6.9 8 0 0 8 8 8 1 HEAT repeat HEAT_2 PF13646.6 OQS06930.1 - 0.0021 18.4 3.0 0.66 10.4 0.0 5.1 4 1 0 5 5 5 1 HEAT repeats CLASP_N PF12348.8 OQS06930.1 - 0.0081 15.7 9.5 0.016 14.8 0.0 4.6 5 0 0 5 5 5 1 CLASP N terminal HMD PF03201.16 OQS06930.1 - 0.06 13.6 0.7 2.6 8.3 0.1 2.8 2 0 0 2 2 2 0 H2-forming N5,N10-methylene-tetrahydromethanopterin dehydrogenase Aminotran_1_2 PF00155.21 OQS06931.1 - 6.9e-35 120.9 0.0 8e-35 120.7 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 OQS06931.1 - 0.00087 18.6 0.0 0.0014 18.0 0.0 1.4 1 0 0 1 1 1 1 Beta-eliminating lyase Spherulin4 PF12138.8 OQS06931.1 - 0.19 11.4 0.0 0.28 10.8 0.0 1.3 1 0 0 1 1 1 0 Spherulation-specific family 4 RnaseA PF00074.20 OQS06932.1 - 0.16 12.4 0.1 16 6.0 0.0 3.1 3 0 0 3 3 3 0 Pancreatic ribonuclease Urb2 PF10441.9 OQS06933.1 - 1.2e-19 71.0 5.9 1.2e-19 71.0 5.9 5.0 3 2 2 5 5 5 1 Urb2/Npa2 family LVIVD PF08309.11 OQS06934.1 - 3.7e-22 77.4 0.0 5e-09 35.3 0.0 6.2 6 0 0 6 6 6 5 LVIVD repeat SBP56 PF05694.11 OQS06934.1 - 0.18 10.6 0.0 0.49 9.1 0.0 1.7 1 1 1 2 2 2 0 56kDa selenium binding protein (SBP56) SPRY PF00622.28 OQS06935.1 - 9.3e-22 77.4 0.1 2.1e-21 76.2 0.1 1.7 1 0 0 1 1 1 1 SPRY domain Telomere_Sde2_2 PF13297.6 OQS06935.1 - 1e-20 73.1 0.0 2.3e-20 72.0 0.0 1.6 1 0 0 1 1 1 1 Telomere stability C-terminal Sde2_N_Ubi PF13019.6 OQS06935.1 - 1.8e-18 66.9 0.3 3.9e-18 65.8 0.3 1.5 1 0 0 1 1 1 1 Silencing defective 2 N-terminal ubiquitin domain zf-CCCH PF00642.24 OQS06935.1 - 0.012 15.5 4.4 0.021 14.7 1.5 2.6 3 0 0 3 3 3 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Sugar-bind PF04198.13 OQS06935.1 - 0.063 12.4 0.0 0.11 11.7 0.0 1.3 1 0 0 1 1 1 0 Putative sugar-binding domain zf-CCCH_4 PF18044.1 OQS06935.1 - 0.1 12.4 1.1 0.31 10.9 1.1 1.8 1 0 0 1 1 1 0 CCCH-type zinc finger zf_CCCH_4 PF18345.1 OQS06935.1 - 1.3 9.2 5.7 0.2 11.8 1.4 1.9 2 0 0 2 2 2 0 Zinc finger domain Tmemb_14 PF03647.13 OQS06937.1 - 7.8e-21 74.6 10.0 9.3e-21 74.4 10.0 1.0 1 0 0 1 1 1 1 Transmembrane proteins 14C Aim19 PF10315.9 OQS06937.1 - 0.0047 17.2 3.4 0.0069 16.7 3.4 1.4 1 1 0 1 1 1 1 Altered inheritance of mitochondria protein 19 His_Phos_2 PF00328.22 OQS06939.1 - 5.9e-74 249.7 0.2 3.1e-70 237.5 0.1 2.1 2 0 0 2 2 2 2 Histidine phosphatase superfamily (branch 2) PPIP5K2_N PF18086.1 OQS06939.1 - 4e-39 132.7 0.1 1.1e-38 131.3 0.1 1.8 1 0 0 1 1 1 1 Diphosphoinositol pentakisphosphate kinase 2 N-terminal domain RimK PF08443.11 OQS06939.1 - 0.0028 17.3 0.0 0.016 14.9 0.0 2.1 2 0 0 2 2 2 1 RimK-like ATP-grasp domain SGL PF08450.12 OQS06940.1 - 1.2e-08 34.9 0.0 1.9e-08 34.2 0.0 1.3 1 0 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region NHL PF01436.21 OQS06940.1 - 9.9e-06 25.3 0.1 0.68 10.1 0.0 4.8 4 0 0 4 4 4 2 NHL repeat CAP PF00188.26 OQS06940.1 - 0.12 13.2 0.5 0.4 11.5 0.2 2.1 2 0 0 2 2 2 0 Cysteine-rich secretory protein family Drc1-Sld2 PF11719.8 OQS06940.1 - 0.16 11.5 0.1 0.23 11.0 0.1 1.1 1 0 0 1 1 1 0 DNA replication and checkpoint protein FHA PF00498.26 OQS06942.1 - 7e-13 48.7 0.0 2.6e-12 46.9 0.0 2.0 2 0 0 2 2 2 1 FHA domain RTT107_BRCT_5 PF16770.5 OQS06942.1 - 0.00087 19.1 0.0 0.0022 17.8 0.0 1.6 1 0 0 1 1 1 1 Regulator of Ty1 transposition protein 107 BRCT domain Yop-YscD_cpl PF16697.5 OQS06942.1 - 0.002 18.4 0.0 0.012 16.0 0.0 2.3 1 1 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain DTW PF03942.15 OQS06942.1 - 0.057 13.1 0.0 1.6 8.4 0.0 2.3 2 0 0 2 2 2 0 DTW domain NumbF PF06311.12 OQS06942.1 - 0.37 11.4 2.4 0.74 10.4 0.2 2.7 2 0 0 2 2 2 0 NUMB domain V-SNARE_C PF12352.8 OQS06943.1 - 1.8e-12 47.3 3.5 8e-12 45.3 3.9 1.9 2 0 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus adh_short PF00106.25 OQS06945.1 - 2.5e-15 56.5 1.4 2.5e-15 56.5 1.4 1.5 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 OQS06945.1 - 3.3e-14 53.0 2.0 4.1e-14 52.7 2.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 OQS06945.1 - 9e-06 25.3 0.3 1.9e-05 24.2 0.3 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family LpxI_N PF17930.1 OQS06945.1 - 0.00095 19.1 0.1 0.0015 18.4 0.1 1.4 1 0 0 1 1 1 1 LpxI N-terminal domain RmlD_sub_bind PF04321.17 OQS06945.1 - 0.0087 15.2 0.5 0.015 14.4 0.5 1.6 1 1 0 1 1 1 1 RmlD substrate binding domain Peptidase_S66 PF02016.15 OQS06945.1 - 0.022 14.9 0.0 0.037 14.1 0.0 1.4 1 0 0 1 1 1 0 LD-carboxypeptidase N-terminal domain FtsJ PF01728.19 OQS06945.1 - 0.089 12.9 0.0 0.14 12.3 0.0 1.2 1 0 0 1 1 1 0 FtsJ-like methyltransferase 2-Hacid_dh_C PF02826.19 OQS06945.1 - 0.09 12.1 0.0 0.2 11.0 0.0 1.6 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain RIH_assoc PF08454.11 OQS06947.1 - 1.6e-17 63.2 0.5 1.6e-17 63.2 0.5 3.6 3 0 0 3 3 3 1 RyR and IP3R Homology associated Ins145_P3_rec PF08709.11 OQS06947.1 - 8.3e-11 41.5 0.6 3.8e-10 39.3 0.3 2.2 1 1 1 2 2 2 1 Inositol 1,4,5-trisphosphate/ryanodine receptor MIR PF02815.19 OQS06947.1 - 1.4e-07 31.5 0.9 1.4e-05 25.1 0.0 3.4 2 1 1 3 3 3 1 MIR domain SAT PF16073.5 OQS06947.1 - 0.049 13.3 0.1 0.11 12.3 0.1 1.5 1 0 0 1 1 1 0 Starter unit:ACP transacylase in aflatoxin biosynthesis RCC1 PF00415.18 OQS06948.1 - 1.1e-05 25.9 0.2 0.0001 22.8 0.0 2.7 3 0 0 3 3 3 1 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 OQS06948.1 - 0.0035 17.1 1.0 0.006 16.3 0.4 1.7 2 0 0 2 2 2 1 Regulator of chromosome condensation (RCC1) repeat SHIPPO-rpt PF07004.12 OQS06948.1 - 0.1 13.6 0.4 0.1 13.6 0.4 3.7 4 0 0 4 4 4 0 Sperm-tail PG-rich repeat DUF1590 PF07629.11 OQS06948.1 - 6.9 6.6 7.3 4.2 7.3 0.1 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF1590) Ank_2 PF12796.7 OQS06949.1 - 9.5e-15 55.0 0.9 3.7e-07 30.6 0.1 3.8 2 1 2 4 4 4 3 Ankyrin repeats (3 copies) START PF01852.19 OQS06949.1 - 7.8e-13 48.3 0.1 6e-07 29.1 0.1 2.8 2 1 0 2 2 2 2 START domain FYVE PF01363.21 OQS06949.1 - 6.5e-10 39.0 15.9 6.5e-10 39.0 15.9 3.6 4 0 0 4 4 4 2 FYVE zinc finger Ank_5 PF13857.6 OQS06949.1 - 2.1e-08 34.2 6.2 1.1 9.7 0.1 6.4 2 1 4 6 6 6 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 OQS06949.1 - 3.5e-08 33.8 7.8 0.0045 17.5 0.3 5.2 1 1 3 4 4 4 4 Ankyrin repeats (many copies) FYVE_2 PF02318.16 OQS06949.1 - 7.1e-07 29.5 31.9 5e-05 23.5 8.1 3.5 4 0 0 4 4 4 2 FYVE-type zinc finger Ank_3 PF13606.6 OQS06949.1 - 0.0017 18.7 5.5 72 4.5 0.1 5.9 7 0 0 7 7 7 0 Ankyrin repeat Ank PF00023.30 OQS06949.1 - 0.012 16.0 2.2 3.8 8.1 0.2 4.1 3 1 1 4 4 4 0 Ankyrin repeat Siva PF05458.12 OQS06949.1 - 8.3 6.1 20.4 4.1 7.1 6.4 2.6 2 0 0 2 2 2 0 Cd27 binding protein (Siva) DUF3811 PF11656.8 OQS06950.1 - 0.0084 16.5 1.0 0.014 15.7 1.0 1.3 1 0 0 1 1 1 1 YjbD family (DUF3811) BT1 PF03092.16 OQS06952.1 - 3.7e-06 25.4 6.7 1.5e-05 23.4 0.7 2.5 2 0 0 2 2 2 2 BT1 family DUF647 PF04884.14 OQS06953.1 - 8.3e-93 310.4 0.5 1.2e-92 309.9 0.5 1.2 1 0 0 1 1 1 1 Vitamin B6 photo-protection and homoeostasis Mntp PF02659.15 OQS06953.1 - 0.097 12.4 1.6 0.19 11.5 0.2 1.9 1 1 1 2 2 2 0 Putative manganese efflux pump COG7 PF10191.9 OQS06954.1 - 9e-50 169.7 17.5 1.2e-48 166.0 17.5 2.2 1 1 0 1 1 1 1 Golgi complex component 7 (COG7) Hepatitis_core PF00906.20 OQS06954.1 - 0.0042 16.7 0.0 0.0071 15.9 0.0 1.3 1 0 0 1 1 1 1 Hepatitis core antigen C2 PF00168.30 OQS06956.1 - 1.2e-16 60.9 0.2 2.9e-16 59.6 0.1 1.6 2 0 0 2 2 2 1 C2 domain DUF2154 PF09922.9 OQS06956.1 - 0.11 12.3 0.0 0.23 11.4 0.0 1.5 1 0 0 1 1 1 0 Cell wall-active antibiotics response 4TMS YvqF NUDIX PF00293.28 OQS06957.1 - 1.8e-15 57.1 0.0 2.6e-15 56.6 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain GTP_EFTU PF00009.27 OQS06958.1 - 5.4e-25 88.1 0.0 7.3e-25 87.6 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 OQS06958.1 - 3.3e-11 43.5 0.3 7.7e-11 42.3 0.3 1.6 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 OQS06958.1 - 2e-07 31.3 0.8 1.8e-05 25.0 0.2 2.9 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 OQS06958.1 - 5.1e-05 23.3 0.0 0.00012 22.1 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 OQS06958.1 - 0.0013 18.3 0.4 0.44 10.1 0.2 2.8 2 1 0 2 2 2 2 Ferrous iron transport protein B RsgA_GTPase PF03193.16 OQS06958.1 - 0.0016 18.4 0.6 0.21 11.5 0.1 2.5 2 0 0 2 2 2 1 RsgA GTPase Roc PF08477.13 OQS06958.1 - 0.0029 17.8 0.0 1 9.6 0.0 2.6 1 1 1 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase ATP_bind_1 PF03029.17 OQS06958.1 - 0.071 12.9 0.0 0.39 10.5 0.0 2.0 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein G-alpha PF00503.20 OQS06958.1 - 0.17 11.0 0.0 2.6 7.1 0.0 2.1 2 0 0 2 2 2 0 G-protein alpha subunit Pkinase PF00069.25 OQS06959.1 - 0.12 11.7 0.0 0.16 11.3 0.0 1.2 1 0 0 1 1 1 0 Protein kinase domain NumbF PF06311.12 OQS06960.1 - 0.31 11.6 1.5 17 6.0 0.1 2.8 3 0 0 3 3 3 0 NUMB domain Methyltransf_25 PF13649.6 OQS06961.1 - 3.4e-10 40.5 0.2 1e-09 39.0 0.0 2.0 2 0 0 2 2 1 1 Methyltransferase domain PrmA PF06325.13 OQS06961.1 - 1.6e-09 37.6 0.1 2.7e-09 36.9 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_11 PF08241.12 OQS06961.1 - 5.6e-08 33.3 0.0 2e-07 31.6 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain PRMT5_C PF17286.2 OQS06961.1 - 5.8e-06 26.3 0.2 1e-05 25.5 0.2 1.4 1 0 0 1 1 1 1 PRMT5 oligomerisation domain MTS PF05175.14 OQS06961.1 - 7.7e-06 25.6 0.0 6e-05 22.7 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase small domain CMAS PF02353.20 OQS06961.1 - 2.4e-05 23.8 0.0 4.5e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.6 OQS06961.1 - 0.0001 22.2 0.0 0.0002 21.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.7 OQS06961.1 - 0.00051 20.0 0.0 0.00095 19.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PRMT5 PF05185.16 OQS06961.1 - 0.0019 18.1 0.0 0.005 16.7 0.0 1.6 2 0 0 2 2 2 1 PRMT5 arginine-N-methyltransferase Methyltransf_9 PF08003.11 OQS06961.1 - 0.0044 16.0 0.0 0.0075 15.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_31 PF13847.6 OQS06961.1 - 0.0045 16.8 0.0 0.0094 15.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.15 OQS06961.1 - 0.11 12.1 0.0 0.2 11.3 0.0 1.4 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Kazal_1 PF00050.21 OQS06961.1 - 0.21 11.6 0.0 0.21 11.6 0.0 3.6 3 0 0 3 3 3 0 Kazal-type serine protease inhibitor domain Kazal_2 PF07648.15 OQS06961.1 - 8.8 6.5 19.9 2.1 8.6 0.0 3.7 3 0 0 3 3 3 0 Kazal-type serine protease inhibitor domain MTHFR PF02219.17 OQS06962.1 - 5.4e-117 390.2 0.0 7.6e-117 389.7 0.0 1.2 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase Lectin_leg-like PF03388.13 OQS06963.1 - 4.8e-36 124.3 0.1 7.3e-36 123.6 0.1 1.2 1 0 0 1 1 1 1 Legume-like lectin family Bact_lectin PF18483.1 OQS06963.1 - 7.1e-09 36.0 2.2 1.2e-08 35.2 2.2 1.3 1 0 0 1 1 1 1 Bacterial lectin Lectin_legB PF00139.19 OQS06963.1 - 1.6e-06 27.8 0.0 4.5e-06 26.4 0.0 1.7 1 1 0 1 1 1 1 Legume lectin domain DCB PF16213.5 OQS06963.1 - 0.028 14.1 0.5 0.046 13.4 0.5 1.2 1 0 0 1 1 1 0 Dimerisation and cyclophilin-binding domain of Mon2 Mod_r PF07200.13 OQS06963.1 - 0.037 14.1 1.0 0.081 13.0 1.0 1.5 1 0 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein MID_MedPIWI PF18296.1 OQS06964.1 - 0.0001 22.2 0.0 0.0034 17.2 0.0 2.5 1 1 0 1 1 1 1 MID domain of medPIWI Med13_C PF06333.12 OQS06964.1 - 0.0093 15.3 0.1 0.0093 15.3 0.1 2.9 3 0 0 3 3 3 1 Mediator complex subunit 13 C-terminal domain Lectin_leg-like PF03388.13 OQS06966.1 - 4.1e-34 117.9 0.0 6.7e-34 117.2 0.0 1.3 1 0 0 1 1 1 1 Legume-like lectin family Bact_lectin PF18483.1 OQS06966.1 - 8.2e-08 32.5 0.6 1.5e-07 31.6 0.1 1.6 2 0 0 2 2 2 1 Bacterial lectin DUF3710 PF12502.8 OQS06966.1 - 0.17 11.6 0.1 0.28 10.8 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3710) UBA_e1_thiolCys PF10585.9 OQS06967.1 - 7.6e-75 252.1 0.3 1e-74 251.6 0.3 1.2 1 0 0 1 1 1 1 Ubiquitin-activating enzyme active site ThiF PF00899.21 OQS06967.1 - 3e-38 131.6 0.0 1.3e-37 129.5 0.0 1.8 1 1 0 1 1 1 1 ThiF family E1_UFD PF09358.10 OQS06967.1 - 3.8e-29 101.2 0.2 1.2e-28 99.6 0.1 2.0 2 0 0 2 2 2 1 Ubiquitin fold domain FTCD PF02971.14 OQS06967.1 - 0.028 14.5 0.2 0.098 12.7 0.0 1.8 2 0 0 2 2 2 0 Formiminotransferase domain DUF3235 PF11574.8 OQS06967.1 - 0.22 12.4 1.5 63 4.5 0.0 3.7 4 1 0 4 4 4 0 Protein of unknown function (DUF3235) Aa_trans PF01490.18 OQS06968.1 - 5.4e-82 275.7 61.6 2.1e-41 142.0 24.6 2.0 2 0 0 2 2 2 2 Transmembrane amino acid transporter protein Flp1_like PF16982.5 OQS06968.1 - 0.00018 20.8 2.7 0.24 10.8 0.3 3.1 2 0 0 2 2 2 2 Putative Flagellin, Flp1-like, domain GramPos_pilinD3 PF16570.5 OQS06968.1 - 0.11 13.2 0.0 13 6.5 0.0 2.3 2 0 0 2 2 2 0 Gram-positive pilin backbone subunit 3, Cna-B-like domain Bromodomain PF00439.25 OQS06969.1 - 2e-20 72.6 0.0 3.9e-20 71.7 0.0 1.5 1 0 0 1 1 1 1 Bromodomain BET PF17035.5 OQS06969.1 - 5.2e-13 48.9 0.8 1.1e-12 47.9 0.8 1.6 1 0 0 1 1 1 1 Bromodomain extra-terminal - transcription regulation SAP18 PF06487.12 OQS06969.1 - 0.03 14.5 0.1 0.064 13.4 0.1 1.6 1 1 0 1 1 1 0 Sin3 associated polypeptide p18 (SAP18) PAP_central PF04928.17 OQS06970.1 - 7.4e-74 247.9 0.0 1e-73 247.4 0.0 1.2 1 0 0 1 1 1 1 Poly(A) polymerase central domain PAP_RNA-bind PF04926.15 OQS06970.1 - 7.8e-18 64.7 0.2 1.9e-10 40.6 0.1 2.4 1 1 1 2 2 2 2 Poly(A) polymerase predicted RNA binding domain NTP_transf_2 PF01909.23 OQS06970.1 - 3e-06 27.4 0.0 7.8e-06 26.1 0.0 1.7 1 0 0 1 1 1 1 Nucleotidyltransferase domain Nrap_D5 PF17406.2 OQS06970.1 - 0.083 12.6 0.0 0.17 11.6 0.0 1.5 1 0 0 1 1 1 0 Nrap protein PAP/OAS1-like domain 5 DUF1729 PF08354.10 OQS06971.1 - 1.6e-141 471.3 0.0 2.7e-141 470.6 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1729) Fas_alpha_ACP PF18325.1 OQS06971.1 - 1.8e-77 259.2 0.0 6.6e-39 133.9 0.0 2.7 2 0 0 2 2 2 2 Fatty acid synthase subunit alpha Acyl carrier domain Acyl_transf_1 PF00698.21 OQS06971.1 - 1.7e-51 175.7 0.0 5.2e-50 170.8 0.0 3.0 2 1 1 3 3 3 1 Acyl transferase domain FAS_I_H PF18314.1 OQS06971.1 - 8.4e-38 130.0 1.3 1.8e-24 86.5 1.3 2.4 2 0 0 2 2 2 2 Fatty acid synthase type I helical domain SAT PF16073.5 OQS06971.1 - 2.2e-33 116.0 1.1 5.6e-33 114.7 0.9 1.9 2 0 0 2 2 2 1 Starter unit:ACP transacylase in aflatoxin biosynthesis TRP PF06011.12 OQS06971.1 - 6.4e-23 81.2 27.6 1.7e-21 76.4 27.6 2.2 1 1 0 1 1 1 1 Transient receptor potential (TRP) ion channel ketoacyl-synt PF00109.26 OQS06971.1 - 1.8e-20 73.6 0.4 1.8e-20 73.6 0.4 2.3 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain FAS_meander PF17951.1 OQS06971.1 - 1.3e-18 67.2 0.2 2.9e-18 66.1 0.2 1.6 1 0 0 1 1 1 1 Fatty acid synthase meander beta sheet domain ACPS PF01648.20 OQS06971.1 - 7.1e-15 55.1 0.0 1.8e-14 53.8 0.0 1.7 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily MaoC_dehydratas PF01575.19 OQS06971.1 - 1.7e-14 53.4 0.0 8.6e-14 51.2 0.0 2.1 2 0 0 2 2 2 1 MaoC like domain Ketoacyl-synt_C PF02801.22 OQS06971.1 - 3.8e-14 52.7 0.0 1e-13 51.3 0.0 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain MaoC_dehydrat_N PF13452.6 OQS06971.1 - 3e-06 27.4 0.0 9.5e-06 25.8 0.0 1.8 1 0 0 1 1 1 1 N-terminal half of MaoC dehydratase Methyltransf_4 PF02390.17 OQS06972.1 - 6e-50 169.1 0.0 7.4e-50 168.8 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_25 PF13649.6 OQS06972.1 - 0.00027 21.6 0.0 0.00047 20.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 OQS06972.1 - 0.0025 17.4 0.0 0.0061 16.1 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.12 OQS06972.1 - 0.028 15.1 0.0 0.058 14.1 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.12 OQS06972.1 - 0.031 14.9 0.0 0.065 13.9 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.6 OQS06972.1 - 0.032 14.0 0.0 0.058 13.2 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain PCMT PF01135.19 OQS06972.1 - 0.071 12.9 0.0 0.11 12.3 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) VirionAssem_T7 PF11653.8 OQS06972.1 - 0.12 12.9 0.0 0.21 12.1 0.0 1.3 1 0 0 1 1 1 0 Bacteriophage T7 virion assembly protein Methyltransf_32 PF13679.6 OQS06972.1 - 0.12 12.3 0.0 0.21 11.6 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain PspB PF06667.12 OQS06973.1 - 0.047 13.8 0.2 0.047 13.8 0.2 2.4 3 0 0 3 3 3 0 Phage shock protein B PDZ_4 PF17816.1 OQS06973.1 - 0.063 13.7 0.1 0.14 12.5 0.0 1.6 2 0 0 2 2 2 0 PDZ domain DUF4407 PF14362.6 OQS06973.1 - 0.12 11.7 0.6 0.18 11.2 0.6 1.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) DUF1664 PF07889.12 OQS06973.1 - 0.31 11.1 1.7 0.31 11.1 0.4 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Ank_2 PF12796.7 OQS06975.1 - 1.1e-06 29.2 3.5 0.00054 20.5 0.3 2.8 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQS06975.1 - 0.00095 19.7 0.2 0.33 11.6 0.3 3.3 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 OQS06975.1 - 0.0021 18.3 1.0 1.1 9.7 0.1 3.4 2 1 1 3 3 3 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQS06975.1 - 0.0072 16.8 0.1 19 6.3 0.1 3.8 2 1 1 3 3 3 1 Ankyrin repeat Cyclin_N PF00134.23 OQS06976.1 - 8.4e-27 93.4 5.4 8.8e-27 93.4 1.9 2.0 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 OQS06976.1 - 6.7e-06 26.2 1.2 1.2e-05 25.3 0.2 1.9 2 0 0 2 2 2 1 Cyclin, C-terminal domain DUF2987 PF11205.8 OQS06976.1 - 0.014 15.4 0.1 0.024 14.6 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2987) Glyco_transf_34 PF05637.12 OQS06977.1 - 4.3e-07 29.9 2.3 0.0018 18.0 1.0 2.2 1 1 1 2 2 2 2 galactosyl transferase GMA12/MNN10 family HSP90 PF00183.18 OQS06978.1 - 7.6e-106 355.0 3.2 4.8e-102 342.5 0.4 2.1 1 1 1 2 2 2 2 Hsp90 protein HATPase_c PF02518.26 OQS06978.1 - 1.2e-10 41.9 0.3 2.6e-10 40.8 0.3 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 OQS06978.1 - 7.8e-10 38.7 0.2 2e-09 37.4 0.2 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Ank_2 PF12796.7 OQS06979.1 - 1.1e-49 166.9 8.8 2.3e-15 57.0 0.2 4.4 1 1 3 5 5 5 5 Ankyrin repeats (3 copies) Ank PF00023.30 OQS06979.1 - 1.2e-37 126.8 9.2 1.1e-06 28.8 0.0 7.3 5 1 1 6 6 6 6 Ankyrin repeat Ank_3 PF13606.6 OQS06979.1 - 1.2e-27 92.9 0.3 0.0012 19.1 0.0 7.4 7 0 0 7 7 7 6 Ankyrin repeat Ank_4 PF13637.6 OQS06979.1 - 3.1e-23 81.8 2.9 2e-08 34.6 0.0 5.6 2 2 3 5 5 5 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 OQS06979.1 - 5.3e-22 77.6 4.9 3.9e-05 23.8 0.0 7.0 2 1 5 7 7 7 6 Ankyrin repeats (many copies) DUF1736 PF08409.11 OQS06980.1 - 1.5e-14 53.7 2.4 5.7e-14 51.9 2.4 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1736) TPR_2 PF07719.17 OQS06980.1 - 2.2e-14 52.3 9.3 0.0044 17.0 0.0 5.9 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_1 PF00515.28 OQS06980.1 - 1.3e-12 46.9 9.2 0.0011 18.7 0.0 6.0 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_12 PF13424.6 OQS06980.1 - 1.1e-07 32.0 0.7 0.79 10.0 0.0 4.7 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 OQS06980.1 - 1e-06 28.5 4.5 8.2 6.9 0.0 5.9 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_19 PF14559.6 OQS06980.1 - 2.7e-05 24.6 0.5 0.011 16.2 0.1 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.6 OQS06980.1 - 0.0001 22.4 0.8 0.99 9.9 0.3 4.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 OQS06980.1 - 0.00021 20.9 8.1 0.11 12.2 0.2 4.3 4 1 1 5 5 5 2 TPR repeat TPR_6 PF13174.6 OQS06980.1 - 0.00046 20.6 1.4 19 6.1 0.0 5.2 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_16 PF13432.6 OQS06980.1 - 0.0026 18.4 0.3 2.5 8.8 0.3 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat DUF2834 PF11196.8 OQS06980.1 - 0.0043 17.4 0.4 0.0043 17.4 0.4 2.8 2 0 0 2 2 2 1 Protein of unknown function (DUF2834) TPR_7 PF13176.6 OQS06980.1 - 0.016 15.2 1.9 14 6.0 0.1 4.7 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_14 PF13428.6 OQS06980.1 - 0.019 15.8 0.1 54 5.0 0.0 3.9 2 1 2 4 4 4 0 Tetratricopeptide repeat MIT PF04212.18 OQS06980.1 - 0.94 9.6 3.1 53 4.0 0.2 3.3 3 0 0 3 3 3 0 MIT (microtubule interacting and transport) domain TPR_10 PF13374.6 OQS06980.1 - 1.3 9.0 8.7 2.1 8.3 0.8 4.3 5 0 0 5 5 4 0 Tetratricopeptide repeat DUF1736 PF08409.11 OQS06981.1 - 1.7e-12 47.1 0.3 5e-12 45.7 0.3 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1736) TPR_2 PF07719.17 OQS06981.1 - 3.6e-05 23.5 0.0 0.011 15.8 0.0 3.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 OQS06981.1 - 0.0011 19.6 1.7 0.054 14.2 0.0 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 OQS06981.1 - 0.0033 17.7 0.4 0.059 13.7 0.0 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 OQS06981.1 - 0.005 16.9 0.1 0.11 12.8 0.0 2.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.6 OQS06981.1 - 0.0076 15.9 0.8 0.99 9.2 0.4 2.9 2 1 1 3 3 3 1 TPR repeat TPR_17 PF13431.6 OQS06981.1 - 0.017 15.5 1.6 1.1 9.8 0.0 2.8 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.28 OQS06981.1 - 0.036 13.9 3.3 0.15 11.9 0.0 3.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_19 PF14559.6 OQS06981.1 - 0.1 13.1 1.1 14 6.3 0.7 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat DnaJ PF00226.31 OQS06982.1 - 4.8e-22 77.8 0.3 7.2e-22 77.3 0.3 1.3 1 0 0 1 1 1 1 DnaJ domain Tmemb_185A PF10269.9 OQS06982.1 - 2.8e-16 60.0 26.8 4.9e-15 55.9 10.8 2.5 1 1 1 2 2 2 2 Transmembrane Fragile-X-F protein CoA_binding_3 PF13727.6 OQS06982.1 - 0.019 15.0 0.6 0.019 15.0 0.6 3.1 4 0 0 4 4 4 0 CoA-binding domain TMEM52 PF14979.6 OQS06982.1 - 0.12 12.3 4.2 0.32 10.9 4.2 1.7 1 0 0 1 1 1 0 Transmembrane 52 TMEM154 PF15102.6 OQS06982.1 - 0.19 11.7 0.1 0.47 10.4 0.1 1.6 1 0 0 1 1 1 0 TMEM154 protein family DUF5381 PF17353.2 OQS06982.1 - 4 7.2 5.8 12 5.6 5.8 1.8 1 0 0 1 1 1 0 Family of unknown function (DUF5381) Comm PF15957.5 OQS06982.1 - 6.1 7.2 10.7 18 5.7 2.8 3.4 3 0 0 3 3 3 0 Commissureless WBP-1 PF11669.8 OQS06982.1 - 6.4 7.5 10.5 8.6 7.1 1.8 3.2 3 0 0 3 3 3 0 WW domain-binding protein 1 TB2_DP1_HVA22 PF03134.19 OQS06983.1 - 5.8e-16 58.2 0.2 9.9e-16 57.4 0.2 1.4 1 0 0 1 1 1 1 TB2/DP1, HVA22 family Ank_2 PF12796.7 OQS06985.1 - 9e-112 365.9 12.9 4.8e-17 62.3 0.0 7.0 1 1 7 9 9 9 9 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQS06985.1 - 8.8e-74 243.0 7.1 2.6e-15 56.6 0.1 9.7 4 3 6 10 10 10 10 Ankyrin repeats (many copies) Ank PF00023.30 OQS06985.1 - 5.5e-68 222.6 18.0 4.8e-07 29.9 0.0 13.1 13 0 0 13 13 13 13 Ankyrin repeat Ank_3 PF13606.6 OQS06985.1 - 6.6e-61 195.1 8.3 3.3e-05 23.9 0.0 13.0 13 0 0 13 13 13 12 Ankyrin repeat Ank_5 PF13857.6 OQS06985.1 - 1.2e-50 168.9 6.0 4.2e-06 26.9 0.0 9.5 5 2 5 10 10 10 10 Ankyrin repeats (many copies) Arg_repressor PF01316.21 OQS06985.1 - 0.044 13.5 4.2 6.5 6.6 0.1 3.8 5 0 0 5 5 5 0 Arginine repressor, DNA binding domain Pribosyltran_N PF13793.6 OQS06986.1 - 3.2e-42 143.1 0.1 1.1e-41 141.4 0.0 1.9 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.6 OQS06986.1 - 8.5e-24 84.6 0.1 3.9e-23 82.5 0.1 1.9 2 0 0 2 2 2 1 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.27 OQS06986.1 - 2.6e-09 36.8 0.1 8.9e-09 35.1 0.1 1.9 2 0 0 2 2 2 1 Phosphoribosyl transferase domain UPRTase PF14681.6 OQS06986.1 - 0.028 13.9 0.0 0.062 12.7 0.0 1.6 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase PRTase_2 PF15609.6 OQS06986.1 - 0.085 12.4 0.1 0.16 11.5 0.1 1.4 1 0 0 1 1 1 0 Phosphoribosyl transferase DUF5353 PF17304.2 OQS06986.1 - 0.19 11.5 1.0 37 4.1 0.1 3.0 3 0 0 3 3 3 0 Family of unknown function (DUF5353) GlcNAc PF11397.8 OQS06987.1 - 2.9e-70 237.5 2.1 4.4e-55 187.6 0.6 2.1 1 1 1 2 2 2 2 Glycosyltransferase (GlcNAc) 2OG-FeII_Oxy_3 PF13640.6 OQS06987.1 - 5.3e-17 62.5 0.0 9.7e-17 61.7 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.6 OQS06987.1 - 7.7e-11 42.5 0.0 1.5e-10 41.6 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Ank_2 PF12796.7 OQS06989.1 - 2.8e-54 181.6 5.0 2.2e-18 66.6 0.2 4.7 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.30 OQS06989.1 - 2.3e-51 170.1 10.0 9e-08 32.2 0.0 9.1 9 0 0 9 9 9 9 Ankyrin repeat Ank_3 PF13606.6 OQS06989.1 - 7.4e-42 136.5 4.6 5.1e-05 23.4 0.0 9.1 9 0 0 9 9 9 8 Ankyrin repeat Ank_4 PF13637.6 OQS06989.1 - 1.6e-39 133.7 5.7 7.6e-13 48.7 0.0 7.2 2 2 6 8 8 8 8 Ankyrin repeats (many copies) Ank_5 PF13857.6 OQS06989.1 - 2.8e-34 116.7 8.9 1.5e-09 37.9 0.0 7.6 2 2 6 8 8 8 7 Ankyrin repeats (many copies) V-SNARE_C PF12352.8 OQS06991.1 - 1.2e-13 51.2 22.3 8.5e-06 26.0 1.3 4.3 4 0 0 4 4 3 3 Snare region anchored in the vesicle membrane C-terminus V-SNARE PF05008.15 OQS06991.1 - 4e-10 39.9 30.2 5.2e-06 26.7 3.1 5.0 6 1 0 6 6 4 2 Vesicle transport v-SNARE protein N-terminus TRP PF06011.12 OQS06991.1 - 0.0019 17.0 0.5 1.3 7.7 0.0 2.7 2 1 1 3 3 3 2 Transient receptor potential (TRP) ion channel Afaf PF15339.6 OQS06991.1 - 0.0037 17.0 1.9 0.47 10.1 0.0 2.9 3 0 0 3 3 3 1 Acrosome formation-associated factor V-ATPase_C PF03223.15 OQS06991.1 - 0.012 15.0 0.6 0.2 11.0 0.0 3.0 3 0 0 3 3 3 0 V-ATPase subunit C Img2 PF05046.14 OQS06991.1 - 0.014 15.7 4.8 10 6.5 0.1 4.3 4 1 1 5 5 4 0 Mitochondrial large subunit ribosomal protein (Img2) YqjK PF13997.6 OQS06991.1 - 0.023 15.0 2.2 5.7 7.3 0.1 3.0 2 0 0 2 2 2 0 YqjK-like protein SNARE PF05739.19 OQS06991.1 - 0.028 14.4 0.2 0.028 14.4 0.2 6.3 5 2 0 5 5 4 0 SNARE domain DUF5089 PF17002.5 OQS06991.1 - 0.033 14.0 0.5 0.033 14.0 0.5 4.5 5 1 0 5 5 4 0 Domain of unknown function (DUF5089) DUF2207 PF09972.9 OQS06991.1 - 0.047 12.5 0.0 1 8.0 0.0 2.5 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF713 PF05218.14 OQS06991.1 - 0.054 13.2 18.2 0.15 11.8 0.3 5.0 5 1 0 5 5 5 0 Protein of unknown function (DUF713) COX6A PF02046.15 OQS06991.1 - 0.067 13.7 1.3 4 8.0 0.1 3.1 3 0 0 3 3 3 0 Cytochrome c oxidase subunit VIa Orf78 PF06024.12 OQS06991.1 - 0.076 13.3 8.4 3.2 8.1 0.2 3.8 3 0 0 3 3 3 0 Orf78 (ac78) T4SS_CagC PF16943.5 OQS06991.1 - 0.099 12.8 0.5 2.5 8.3 0.0 3.1 3 0 0 3 3 3 0 Cag pathogenicity island, type IV secretory system CCDC-167 PF15188.6 OQS06991.1 - 0.1 12.9 23.8 0.096 13.0 2.1 5.6 4 1 1 5 5 5 0 Coiled-coil domain-containing protein 167 E1-E2_ATPase PF00122.20 OQS06991.1 - 0.22 11.0 5.0 9.5 5.7 0.1 3.1 3 0 0 3 3 3 0 E1-E2 ATPase Fusion_gly PF00523.18 OQS06991.1 - 0.25 9.5 5.7 2 6.6 0.2 3.2 3 0 0 3 3 3 0 Fusion glycoprotein F0 DUF1206 PF06724.11 OQS06991.1 - 0.27 11.3 4.6 5.7 7.1 0.1 3.2 3 0 0 3 3 3 0 Domain of Unknown Function (DUF1206) Laminin_II PF06009.12 OQS06991.1 - 0.32 11.0 28.4 0.076 13.0 0.5 5.8 6 1 0 6 6 6 0 Laminin Domain II FliJ PF02050.16 OQS06991.1 - 1.2 9.4 46.2 0.42 10.8 1.7 6.3 6 0 0 6 6 6 0 Flagellar FliJ protein Retrotrans_gag PF03732.17 OQS06991.1 - 1.4 9.3 7.6 0.66 10.3 0.1 4.0 4 2 0 4 4 2 0 Retrotransposon gag protein GPDPase_memb PF10110.9 OQS06991.1 - 2.4 6.9 10.6 0.41 9.4 0.5 2.4 3 0 0 3 3 3 0 Membrane domain of glycerophosphoryl diester phosphodiesterase DUF948 PF06103.11 OQS06991.1 - 3 8.2 14.2 46 4.4 0.0 6.1 6 1 1 7 7 7 0 Bacterial protein of unknown function (DUF948) YnfE PF17452.2 OQS06991.1 - 3.4 8.0 17.2 3.5 8.0 0.1 4.4 5 0 0 5 5 5 0 Uncharacterized YnfE-like DUF1664 PF07889.12 OQS06991.1 - 4.1 7.5 23.5 0.24 11.5 0.8 5.6 6 0 0 6 6 6 0 Protein of unknown function (DUF1664) Amidohydro_1 PF01979.20 OQS06992.1 - 3.2e-19 69.4 0.6 4.7e-19 68.9 0.6 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_2 PF04909.14 OQS06992.1 - 0.0033 17.2 0.1 0.0068 16.2 0.1 1.6 1 1 0 1 1 1 1 Amidohydrolase Peptidase_S24 PF00717.23 OQS06994.1 - 3e-10 39.9 0.1 7e-10 38.7 0.0 1.6 1 1 1 2 2 2 1 Peptidase S24-like Peptidase_S26 PF10502.9 OQS06994.1 - 8.8e-07 28.8 0.1 0.00038 20.3 0.0 2.5 2 1 0 2 2 2 2 Signal peptidase, peptidase S26 Clathrin_lg_ch PF01086.17 OQS06995.1 - 9.2e-09 35.7 13.7 2e-07 31.3 13.7 2.0 1 1 0 1 1 1 1 Clathrin light chain SHOCT PF09851.9 OQS06995.1 - 0.039 13.7 0.6 0.039 13.7 0.6 3.3 3 0 0 3 3 3 0 Short C-terminal domain DUF883 PF05957.13 OQS06995.1 - 0.092 13.4 11.8 0.075 13.6 4.5 2.2 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) Mito_carr PF00153.27 OQS06996.1 - 5.4e-31 106.4 8.4 1.1e-17 63.8 0.1 3.6 3 1 0 3 3 3 3 Mitochondrial carrier protein Sds3 PF08598.11 OQS06997.1 - 1.8e-07 31.4 4.4 2.4e-07 31.0 4.4 1.1 1 0 0 1 1 1 1 Sds3-like HATPase_c_4 PF13749.6 OQS06997.1 - 0.11 12.6 0.1 11 6.2 0.1 2.2 1 1 1 2 2 2 0 Putative ATP-dependent DNA helicase recG C-terminal Sec61_beta PF03911.16 OQS06998.1 - 3.9e-20 71.6 0.1 4.9e-20 71.3 0.1 1.1 1 0 0 1 1 1 1 Sec61beta family NUDIX PF00293.28 OQS06999.1 - 1.6e-18 67.0 0.0 2.3e-18 66.5 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain Ank_2 PF12796.7 OQS07000.1 - 1.5e-07 31.9 0.1 1.8e-06 28.4 0.1 2.0 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OQS07000.1 - 1.1e-06 28.8 0.0 0.018 15.4 0.0 2.7 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 OQS07000.1 - 2.8e-05 24.6 0.1 0.58 10.8 0.0 2.6 1 1 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQS07000.1 - 0.00022 21.4 0.0 2.5 8.9 0.0 3.5 4 0 0 4 4 4 1 Ankyrin repeat DUF5049 PF16468.5 OQS07000.1 - 0.027 14.4 0.2 5.5 7.0 0.0 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF5049) Ribosomal_S17 PF00366.20 OQS07001.1 - 7e-28 96.5 1.4 8.4e-28 96.3 1.4 1.1 1 0 0 1 1 1 1 Ribosomal protein S17 DUF4542 PF15075.6 OQS07002.1 - 0.02 15.3 0.2 0.025 15.0 0.2 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4542) DUF4692 PF15763.5 OQS07002.1 - 0.26 11.7 3.3 0.34 11.4 3.3 1.1 1 0 0 1 1 1 0 Regulator of human erythroid cell expansion (RHEX) WD40_like PF17005.5 OQS07003.1 - 0.0015 17.9 0.0 0.14 11.4 0.0 2.4 2 1 0 2 2 2 2 WD40-like domain PQQ_3 PF13570.6 OQS07003.1 - 0.0026 18.2 0.0 0.016 15.7 0.0 2.3 2 0 0 2 2 2 1 PQQ-like domain WD40 PF00400.32 OQS07003.1 - 0.0034 18.2 0.0 3 8.9 0.0 3.6 3 0 0 3 3 3 1 WD domain, G-beta repeat PQQ_2 PF13360.6 OQS07003.1 - 0.0072 15.9 0.1 1.2 8.7 0.0 2.8 2 1 0 2 2 2 1 PQQ-like domain PPP1R26_N PF15740.5 OQS07003.1 - 0.078 11.6 2.1 0.095 11.3 2.1 1.1 1 0 0 1 1 1 0 Protein phosphatase 1 regulatory subunit 26 N-terminus SART-1 PF03343.13 OQS07004.1 - 2.6e-68 231.2 43.1 2.6e-68 231.2 43.1 1.9 2 0 0 2 2 2 1 SART-1 family DUF3619 PF12279.8 OQS07004.1 - 0.11 12.8 2.4 0.3 11.4 0.3 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3619) XRN_N PF03159.18 OQS07005.1 - 6e-93 310.7 0.1 1.8e-92 309.2 0.0 1.9 2 0 0 2 2 2 1 XRN 5'-3' exonuclease N-terminus XRN_M PF17846.1 OQS07005.1 - 1.5e-82 277.9 0.4 3.8e-58 197.5 0.5 2.4 2 0 0 2 2 2 2 Xrn1 helical domain XRN1_D1 PF18332.1 OQS07005.1 - 6e-28 97.9 0.0 1.2e-27 96.9 0.0 1.5 1 0 0 1 1 1 1 Exoribonuclease Xrn1 D1 domain SH3_12 PF18129.1 OQS07005.1 - 7.8e-19 67.5 0.1 5.6e-18 64.8 0.0 2.2 2 0 0 2 2 2 1 Xrn1 SH3-like domain XRN1_D2_D3 PF18334.1 OQS07005.1 - 1.5e-05 25.1 0.0 4.8e-05 23.5 0.0 1.9 1 0 0 1 1 1 1 Exoribonuclease Xrn1 D2/D3 domain CX9C PF16860.5 OQS07006.1 - 0.093 12.8 0.4 0.53 10.3 0.3 2.0 1 1 1 2 2 2 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, Ysc84 PF04366.12 OQS07007.1 - 1.3e-36 125.2 0.9 2e-36 124.6 0.9 1.3 1 0 0 1 1 1 1 Las17-binding protein actin regulator His_biosynth PF00977.21 OQS07008.1 - 1.1e-29 103.6 0.0 1.4e-29 103.2 0.0 1.1 1 0 0 1 1 1 1 Histidine biosynthesis protein Ephrin_rec_like PF07699.13 OQS07009.1 - 3.3e-05 23.5 4.8 5e-05 23.0 3.1 2.1 2 0 0 2 2 2 1 Putative ephrin-receptor like Erf4 PF10256.9 OQS07009.1 - 0.046 13.8 0.1 0.98 9.5 0.0 2.8 3 0 0 3 3 3 0 Golgin subfamily A member 7/ERF4 family Laminin_EGF PF00053.24 OQS07009.1 - 3.3 7.9 7.8 22 5.3 1.2 2.7 1 1 1 2 2 2 0 Laminin EGF domain EF-hand_8 PF13833.6 OQS07010.1 - 1.9e-10 40.4 0.6 5.8e-10 38.9 0.1 2.1 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_7 PF13499.6 OQS07010.1 - 1.1e-05 25.7 2.7 0.0079 16.6 0.5 3.3 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 OQS07010.1 - 0.00054 19.3 0.2 0.0028 17.1 0.2 2.3 1 0 0 1 1 1 1 EF hand NanE PF04131.14 OQS07010.1 - 0.015 14.5 0.1 0.022 14.0 0.1 1.2 1 0 0 1 1 1 0 Putative N-acetylmannosamine-6-phosphate epimerase EF-hand_6 PF13405.6 OQS07010.1 - 0.07 13.1 2.3 3.8 7.7 0.1 3.5 4 0 0 4 4 4 0 EF-hand domain Shigella_OspC PF06128.11 OQS07011.1 - 0.024 14.3 0.0 0.034 13.9 0.0 1.2 1 0 0 1 1 1 0 Shigella flexneri OspC protein Porin_3 PF01459.22 OQS07013.1 - 5.1e-42 144.2 11.4 6.1e-42 143.9 11.4 1.0 1 0 0 1 1 1 1 Eukaryotic porin tRNA-synt_1e PF01406.19 OQS07014.1 - 6.8e-122 406.5 0.0 1.7e-120 401.9 0.1 2.3 2 0 0 2 2 2 1 tRNA synthetases class I (C) catalytic domain S4 PF01479.25 OQS07014.1 - 2.3e-08 33.6 0.3 6.3e-08 32.2 0.3 1.8 1 0 0 1 1 1 1 S4 domain DALR_2 PF09190.11 OQS07014.1 - 1.9e-07 31.4 3.2 3.3e-07 30.7 0.0 2.8 2 0 0 2 2 2 1 DALR domain tRNA-synt_1g PF09334.11 OQS07014.1 - 8.9e-06 24.7 0.8 9.3e-05 21.3 0.1 2.4 2 0 0 2 2 2 1 tRNA synthetases class I (M) Ribosomal_S4 PF00163.19 OQS07014.1 - 1.2e-05 26.1 0.9 5e-05 24.1 0.6 2.3 1 1 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain tRNA-synt_1c PF00749.21 OQS07014.1 - 0.00084 18.3 0.0 0.00084 18.3 0.0 2.9 3 0 0 3 3 3 1 tRNA synthetases class I (E and Q), catalytic domain Dna2 PF08696.11 OQS07014.1 - 0.072 12.9 0.1 0.16 11.7 0.1 1.5 1 0 0 1 1 1 0 DNA replication factor Dna2 Radial_spoke_3 PF06098.11 OQS07014.1 - 1.8 7.8 11.3 4 6.6 11.3 1.5 1 0 0 1 1 1 0 Radial spoke protein 3 Remorin_C PF03763.13 OQS07014.1 - 3.8 7.4 16.3 0.24 11.3 8.3 2.6 2 0 0 2 2 2 0 Remorin, C-terminal region DUF4131 PF13567.6 OQS07015.1 - 0.014 15.0 0.2 0.022 14.4 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) QH-AmDH_gamma PF08992.11 OQS07015.1 - 0.12 12.4 0.0 0.29 11.2 0.0 1.6 1 0 0 1 1 1 0 Quinohemoprotein amine dehydrogenase, gamma subunit Lact_bio_phlase PF09508.10 OQS07015.1 - 0.15 10.4 0.2 0.22 9.9 0.2 1.1 1 0 0 1 1 1 0 Lacto-N-biose phosphorylase N-terminal TIM barrel domain FKBP_C PF00254.28 OQS07016.1 - 0.0017 18.7 0.0 0.0042 17.4 0.0 1.7 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase WH1 PF00568.23 OQS07016.1 - 0.065 13.2 0.4 0.23 11.4 0.2 2.0 2 0 0 2 2 2 0 WH1 domain Ribosomal_S21e PF01249.18 OQS07017.1 - 1.8e-36 124.1 0.1 2.2e-36 123.8 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S21e TRAPPC9-Trs120 PF08626.11 OQS07018.1 - 8.9e-25 86.3 0.1 7.5e-19 66.7 0.0 2.9 3 0 0 3 3 3 3 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit Ank_2 PF12796.7 OQS07019.1 - 9e-34 115.9 17.6 1.7e-08 34.9 0.2 7.5 2 2 5 7 7 7 7 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OQS07019.1 - 4.8e-33 112.8 16.5 0.00035 20.8 0.1 12.5 5 3 9 14 14 14 9 Ankyrin repeats (many copies) Ank_4 PF13637.6 OQS07019.1 - 6.2e-27 93.6 12.8 1.9e-05 25.1 0.1 9.9 5 3 7 12 12 12 9 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQS07019.1 - 5e-19 66.4 12.7 1.2 9.9 0.0 12.6 13 1 1 14 14 14 4 Ankyrin repeat DUF5049 PF16468.5 OQS07019.1 - 1.2e-08 34.7 4.0 5.1 7.1 0.0 8.0 5 1 4 9 9 9 1 Domain of unknown function (DUF5049) Ank PF00023.30 OQS07019.1 - 0.00076 19.8 5.7 22 5.7 0.0 7.7 7 1 1 8 8 8 0 Ankyrin repeat CNOT1_HEAT PF16418.5 OQS07019.1 - 0.01 16.0 0.5 4.3 7.4 0.0 4.2 4 1 1 5 5 5 1 CCR4-NOT transcription complex subunit 1 HEAT repeat Tim44 PF04280.15 OQS07019.1 - 0.056 13.5 0.4 1.1 9.4 0.1 2.6 2 0 0 2 2 2 0 Tim44-like domain AhpC-TSA PF00578.21 OQS07019.1 - 0.064 13.2 0.3 18 5.2 0.0 3.9 1 1 4 5 5 5 0 AhpC/TSA family Sushi_2 PF09014.10 OQS07019.1 - 0.71 9.8 3.5 1.4 8.8 0.1 3.0 3 0 0 3 3 3 0 Beta-2-glycoprotein-1 fifth domain Plasmod_dom_1 PF09715.10 OQS07019.1 - 2.7 8.1 9.4 0.28 11.3 0.3 3.8 4 1 1 5 5 5 0 Plasmodium protein of unknown function (Plasmod_dom_1) Ion_trans PF00520.31 OQS07020.1 - 2.3e-31 108.9 62.0 1.9e-23 82.9 21.0 2.5 2 1 0 2 2 2 2 Ion transport protein FAM176 PF14851.6 OQS07020.1 - 0.066 12.9 1.9 0.84 9.3 0.0 2.3 2 0 0 2 2 2 0 FAM176 family Ubiquitin_2 PF14560.6 OQS07021.1 - 2.2e-25 88.9 0.0 3.4e-25 88.3 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-like domain CAP_GLY PF01302.25 OQS07021.1 - 3.8e-19 68.5 2.8 7.9e-19 67.4 2.8 1.6 1 0 0 1 1 1 1 CAP-Gly domain ubiquitin PF00240.23 OQS07021.1 - 0.00091 18.9 0.3 0.0028 17.4 0.0 1.9 2 1 0 2 2 2 1 Ubiquitin family SH3_12 PF18129.1 OQS07021.1 - 0.025 14.7 0.6 1.1 9.4 0.0 2.6 1 1 1 2 2 2 0 Xrn1 SH3-like domain KH_6 PF15985.5 OQS07022.1 - 1.4e-13 51.0 0.1 2.2e-13 50.3 0.1 1.4 1 0 0 1 1 1 1 KH domain Rrp40_N PF18311.1 OQS07022.1 - 0.00031 20.6 0.0 0.00062 19.6 0.0 1.5 1 0 0 1 1 1 1 Exosome complex exonuclease Rrp40 N-terminal domain CRR7 PF12095.8 OQS07023.1 - 0.086 13.3 0.5 0.086 13.3 0.5 2.3 2 1 1 3 3 3 0 Protein CHLORORESPIRATORY REDUCTION 7 SlyX PF04102.12 OQS07023.1 - 5.5 7.7 9.7 0.32 11.6 0.6 2.8 2 2 0 2 2 2 0 SlyX Snf7 PF03357.21 OQS07024.1 - 1.3e-44 151.9 12.9 1.8e-44 151.4 12.9 1.3 1 0 0 1 1 1 1 Snf7 CCDC24 PF15669.5 OQS07024.1 - 0.04 13.8 9.2 0.09 12.6 2.4 2.4 1 1 1 2 2 2 0 Coiled-coil domain-containing protein 24 family FapA PF03961.13 OQS07024.1 - 0.11 11.1 4.5 0.16 10.5 4.5 1.4 1 0 0 1 1 1 0 Flagellar Assembly Protein A Fmp27_WPPW PF10359.9 OQS07024.1 - 0.27 10.1 5.0 0.31 9.8 5.0 1.2 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain DUF5082 PF16888.5 OQS07024.1 - 0.31 11.3 12.2 0.096 13.0 0.8 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF5082) DUF948 PF06103.11 OQS07024.1 - 0.41 10.9 3.0 7.5 6.9 0.3 2.5 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) NPR2 PF06218.11 OQS07024.1 - 0.43 9.3 3.8 0.2 10.4 1.1 1.7 1 1 1 2 2 2 0 Nitrogen permease regulator 2 Fib_alpha PF08702.10 OQS07024.1 - 1.2 9.3 7.5 1.9 8.6 4.8 2.1 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Ubiq_cyt_C_chap PF03981.12 OQS07025.1 - 1.4e-18 67.4 0.0 1.9e-18 66.9 0.0 1.2 1 0 0 1 1 1 1 Ubiquinol-cytochrome C chaperone WW PF00397.26 OQS07025.1 - 0.00041 20.4 0.2 0.00094 19.2 0.2 1.6 1 0 0 1 1 1 1 WW domain SET PF00856.28 OQS07026.1 - 3.6e-12 47.0 0.0 1.5e-11 45.0 0.0 1.8 1 1 0 1 1 1 1 SET domain SET PF00856.28 OQS07027.1 - 2.8e-07 31.1 0.7 2.8e-07 31.1 0.7 1.8 2 1 0 2 2 2 1 SET domain T2SSL PF05134.13 OQS07027.1 - 0.21 10.9 1.8 1.8 7.8 1.8 2.0 1 1 0 1 1 1 0 Type II secretion system (T2SS), protein L Ras PF00071.22 OQS07028.1 - 1.4e-06 28.0 0.0 0.0064 16.1 0.0 2.4 2 0 0 2 2 2 2 Ras family Roc PF08477.13 OQS07028.1 - 4.3e-06 27.0 0.0 0.00012 22.3 0.0 2.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OQS07028.1 - 0.014 14.8 0.4 0.082 12.4 0.0 2.2 2 0 0 2 2 2 0 ADP-ribosylation factor family MMR_HSR1 PF01926.23 OQS07028.1 - 0.018 15.1 0.0 0.05 13.7 0.0 1.8 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_16 PF13191.6 OQS07028.1 - 0.03 14.7 0.0 0.079 13.3 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain Sigma54_activat PF00158.26 OQS07028.1 - 0.068 12.9 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain ABC_tran PF00005.27 OQS07028.1 - 0.096 13.2 0.4 0.58 10.7 0.0 2.5 2 0 0 2 2 2 0 ABC transporter Spt4 PF06093.13 OQS07029.1 - 7.7e-34 115.6 0.7 9.8e-34 115.3 0.7 1.1 1 0 0 1 1 1 1 Spt4/RpoE2 zinc finger Myosin_head PF00063.21 OQS07030.1 - 1.3e-101 340.9 0.0 3.1e-99 333.1 0.0 2.9 1 1 0 1 1 1 1 Myosin head (motor domain) RCC1 PF00415.18 OQS07030.1 - 1.1e-52 176.4 9.1 1.9e-12 47.6 0.3 5.4 5 0 0 5 5 5 4 Regulator of chromosome condensation (RCC1) repeat G10 PF01125.17 OQS07030.1 - 1.6e-52 177.2 2.4 1.6e-52 177.2 2.4 2.1 2 0 0 2 2 1 1 G10 protein RCC1_2 PF13540.6 OQS07030.1 - 4e-26 90.2 24.3 2.2e-08 33.6 3.3 6.2 6 0 0 6 6 6 4 Regulator of chromosome condensation (RCC1) repeat IQ PF00612.27 OQS07030.1 - 1.4e-06 27.5 39.2 0.051 13.4 0.5 6.3 6 0 0 6 6 6 5 IQ calmodulin-binding motif AAA_16 PF13191.6 OQS07030.1 - 0.0041 17.5 0.0 0.017 15.5 0.0 2.1 1 0 0 1 1 1 1 AAA ATPase domain Mg_chelatase PF01078.21 OQS07030.1 - 0.0075 15.7 0.0 0.015 14.7 0.0 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI CDC45 PF02724.14 OQS07030.1 - 0.013 13.9 9.0 0.025 12.9 9.0 1.4 1 0 0 1 1 1 0 CDC45-like protein AAA_22 PF13401.6 OQS07030.1 - 0.017 15.4 0.0 0.062 13.6 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 OQS07030.1 - 0.035 13.9 0.0 0.11 12.2 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain Zeta_toxin PF06414.12 OQS07030.1 - 0.036 13.3 0.0 0.076 12.3 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin NACHT PF05729.12 OQS07030.1 - 0.046 13.6 0.0 0.14 12.0 0.0 1.9 1 0 0 1 1 1 0 NACHT domain DUF87 PF01935.17 OQS07030.1 - 0.047 13.8 1.4 0.29 11.2 0.1 2.7 2 0 0 2 2 2 0 Helicase HerA, central domain AAA_19 PF13245.6 OQS07030.1 - 0.047 14.0 0.0 0.12 12.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 OQS07030.1 - 0.068 13.2 0.0 0.19 11.7 0.0 1.8 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Torsin PF06309.11 OQS07030.1 - 0.072 13.2 0.5 0.36 10.9 0.0 2.3 3 0 0 3 3 2 0 Torsin AAA_25 PF13481.6 OQS07030.1 - 0.073 12.6 0.1 0.26 10.8 0.0 1.9 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 OQS07030.1 - 0.075 13.5 0.0 0.26 11.8 0.0 1.9 1 0 0 1 1 1 0 ABC transporter AAA_PrkA PF08298.11 OQS07030.1 - 0.082 11.8 0.0 0.14 11.0 0.0 1.2 1 0 0 1 1 1 0 PrkA AAA domain RsgA_GTPase PF03193.16 OQS07030.1 - 0.085 12.7 0.0 0.33 10.8 0.0 1.9 2 0 0 2 2 2 0 RsgA GTPase AAA_18 PF13238.6 OQS07030.1 - 0.098 13.2 0.0 0.38 11.3 0.0 2.1 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 OQS07030.1 - 0.099 12.8 0.0 0.35 11.0 0.0 1.9 1 0 0 1 1 1 0 AAA domain PRK PF00485.18 OQS07030.1 - 0.11 12.2 0.0 0.25 11.0 0.0 1.6 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family DUF4719 PF15843.5 OQS07030.1 - 0.13 12.4 0.0 0.27 11.3 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4719) APS_kinase PF01583.20 OQS07030.1 - 0.15 11.9 0.0 0.29 11.0 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase SDA1 PF05285.12 OQS07030.1 - 0.92 8.9 17.6 1.9 7.8 17.6 1.4 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 OQS07030.1 - 4.5 5.3 17.2 7.3 4.7 17.2 1.2 1 0 0 1 1 1 0 Nop14-like family DUF913 PF06025.12 OQS07030.1 - 5.6 5.8 7.1 7 5.5 5.3 1.9 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) SURF2 PF05477.11 OQS07030.1 - 9.7 5.8 10.7 21 4.7 10.7 1.5 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) Nicastrin PF05450.15 OQS07032.1 - 3.5e-23 82.3 1.8 7.2e-23 81.3 1.8 1.5 1 1 0 1 1 1 1 Nicastrin Ncstrn_small PF18266.1 OQS07032.1 - 1.9e-16 60.6 0.0 4.5e-16 59.3 0.0 1.6 1 0 0 1 1 1 1 Nicastrin small lobe Peptidase_M28 PF04389.17 OQS07032.1 - 2.6e-13 50.1 0.0 5.8e-13 49.0 0.0 1.6 1 1 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.28 OQS07032.1 - 0.043 13.5 0.0 0.071 12.8 0.0 1.3 1 0 0 1 1 1 0 Peptidase family M20/M25/M40 SAM_decarbox PF01536.16 OQS07033.1 - 1.9e-103 346.2 0.0 2.3e-103 346.0 0.0 1.0 1 0 0 1 1 1 1 Adenosylmethionine decarboxylase SF3b10 PF07189.11 OQS07034.1 - 7.8e-41 138.1 0.0 8.7e-41 137.9 0.0 1.0 1 0 0 1 1 1 1 Splicing factor 3B subunit 10 (SF3b10) DUF3546 PF12066.8 OQS07035.1 - 1.2e-15 57.6 6.9 2.9e-15 56.4 6.9 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3546) ARS2 PF04959.13 OQS07035.1 - 7.8e-14 52.5 0.3 2e-13 51.2 0.3 1.7 1 0 0 1 1 1 1 Arsenite-resistance protein 2 DUF4187 PF13821.6 OQS07035.1 - 0.0047 16.7 0.0 0.016 15.0 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4187) zf-C2H2_12 PF18658.1 OQS07035.1 - 0.006 16.1 0.3 0.053 13.1 0.1 2.3 2 0 0 2 2 2 1 Zinc-finger C2H2-type zf-C2H2_2 PF12756.7 OQS07035.1 - 0.018 15.4 0.3 0.067 13.5 0.0 2.1 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) GDH_N PF12466.8 OQS07035.1 - 0.046 13.9 0.3 0.2 11.9 0.0 2.2 2 0 0 2 2 2 0 Glutamate dehydrogenase N terminal zf-C2H2 PF00096.26 OQS07035.1 - 0.36 11.4 3.8 0.8 10.3 3.8 1.7 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 OQS07035.1 - 0.83 10.7 3.3 2.4 9.2 3.3 1.9 1 0 0 1 1 1 0 C2H2-type zinc finger THRAP3_BCLAF1 PF15440.6 OQS07035.1 - 4.6 6.1 20.5 6.6 5.6 20.5 1.2 1 0 0 1 1 1 0 THRAP3/BCLAF1 family AAA PF00004.29 OQS07036.1 - 3.4e-10 40.4 0.1 4.8e-09 36.7 0.0 2.5 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 OQS07036.1 - 1.8e-09 38.0 0.0 7.8e-09 35.9 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 OQS07036.1 - 3.3e-05 23.7 0.0 7.9e-05 22.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 OQS07036.1 - 0.0001 22.7 0.2 0.0014 19.1 0.0 2.7 2 1 0 2 2 2 1 AAA ATPase domain ResIII PF04851.15 OQS07036.1 - 0.0027 17.7 0.2 0.021 14.9 0.1 2.7 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit PIF1 PF05970.14 OQS07036.1 - 0.0049 16.1 0.3 0.0086 15.3 0.3 1.3 1 0 0 1 1 1 1 PIF1-like helicase TniB PF05621.11 OQS07036.1 - 0.0057 16.1 0.0 0.013 14.9 0.0 1.5 1 0 0 1 1 1 1 Bacterial TniB protein NACHT PF05729.12 OQS07036.1 - 0.044 13.7 0.0 0.11 12.4 0.0 1.7 1 0 0 1 1 1 0 NACHT domain Transposase_24 PF03004.14 OQS07036.1 - 0.044 13.9 2.0 0.14 12.2 2.0 1.9 1 0 0 1 1 1 0 Plant transposase (Ptta/En/Spm family) AAA_28 PF13521.6 OQS07036.1 - 0.064 13.5 0.0 1.4 9.2 0.0 2.6 2 0 0 2 2 2 0 AAA domain Sigma54_activat PF00158.26 OQS07036.1 - 0.069 12.8 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_19 PF13245.6 OQS07036.1 - 0.072 13.4 0.1 0.19 12.1 0.1 1.8 1 1 0 1 1 1 0 AAA domain AAA_lid_10 PF17872.1 OQS07036.1 - 0.078 13.1 0.0 0.54 10.4 0.0 2.3 2 0 0 2 2 2 0 AAA lid domain CPT PF07931.12 OQS07036.1 - 0.088 12.6 0.0 0.18 11.6 0.0 1.4 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein AAA_7 PF12775.7 OQS07036.1 - 0.11 12.0 0.2 0.22 11.0 0.2 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region CRAL_TRIO_N PF03765.15 OQS07036.1 - 0.8 9.9 2.7 6.1 7.1 0.0 3.6 3 0 0 3 3 3 0 CRAL/TRIO, N-terminal domain zf-C2H2 PF00096.26 OQS07037.1 - 4.5e-18 64.6 28.7 0.0001 22.5 2.3 4.9 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 OQS07037.1 - 7.4e-14 51.3 29.1 0.0019 18.9 2.8 5.0 5 0 0 5 5 5 4 C2H2-type zinc finger zf-H2C2_2 PF13465.6 OQS07037.1 - 1e-13 51.0 28.3 0.0003 21.1 2.4 5.4 5 0 0 5 5 5 3 Zinc-finger double domain zf-H2C2_5 PF13909.6 OQS07037.1 - 2.8e-05 23.8 21.4 0.16 11.8 0.6 5.1 4 1 0 4 4 4 3 C2H2-type zinc-finger domain zf-TRAF PF02176.18 OQS07037.1 - 0.00051 20.7 10.4 0.022 15.5 0.7 2.4 2 0 0 2 2 2 2 TRAF-type zinc finger zf-C2H2_8 PF15909.5 OQS07037.1 - 0.0007 19.8 13.1 0.095 13.0 8.1 2.8 1 1 1 2 2 2 2 C2H2-type zinc ribbon zf-C2H2_aberr PF17017.5 OQS07037.1 - 0.012 15.8 9.2 0.76 9.9 0.0 3.4 2 1 1 3 3 3 0 Aberrant zinc-finger zf-C2H2_6 PF13912.6 OQS07037.1 - 0.033 14.2 2.8 0.033 14.2 2.8 4.9 5 0 0 5 5 5 0 C2H2-type zinc finger DUF5579 PF17742.1 OQS07037.1 - 0.26 10.8 1.6 4 6.9 0.2 2.3 1 1 1 2 2 2 0 Family of unknown function (DUF5579) FOXP-CC PF16159.5 OQS07037.1 - 0.89 10.2 9.0 32 5.2 0.2 4.2 1 1 3 4 4 4 0 FOXP coiled-coil domain Pkinase PF00069.25 OQS07038.1 - 7.9e-54 182.8 0.0 1.2e-53 182.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQS07038.1 - 2.6e-22 79.4 0.0 3.7e-22 78.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase cNMP_binding PF00027.29 OQS07038.1 - 1.1e-05 25.4 0.0 2.3e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Pkinase_fungal PF17667.1 OQS07038.1 - 0.00014 20.8 0.0 0.0003 19.7 0.0 1.5 2 0 0 2 2 2 1 Fungal protein kinase Haspin_kinase PF12330.8 OQS07038.1 - 0.014 14.4 0.0 0.027 13.4 0.0 1.4 1 0 0 1 1 1 0 Haspin like kinase domain Kdo PF06293.14 OQS07038.1 - 0.091 12.1 0.0 0.17 11.2 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.11 OQS07038.1 - 0.11 11.6 0.0 0.17 10.9 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 PIG-U PF06728.13 OQS07039.1 - 1.6e-85 287.5 39.1 1.8e-85 287.3 39.1 1.0 1 0 0 1 1 1 1 GPI transamidase subunit PIG-U CSD PF00313.22 OQS07040.1 - 9.6e-15 54.2 0.2 1.4e-14 53.7 0.2 1.2 1 0 0 1 1 1 1 'Cold-shock' DNA-binding domain OB_RNB PF08206.11 OQS07040.1 - 1e-05 25.1 0.3 3e-05 23.6 0.3 1.8 1 0 0 1 1 1 1 Ribonuclease B OB domain zf_CCCH_4 PF18345.1 OQS07040.1 - 1.8e-05 24.6 9.4 2.7e-05 24.0 7.8 2.1 2 0 0 2 2 2 1 Zinc finger domain zf-CCCH PF00642.24 OQS07040.1 - 0.00016 21.5 6.8 0.00016 21.5 6.8 1.9 2 0 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 OQS07040.1 - 0.0011 18.7 7.3 0.0023 17.7 7.3 1.6 1 0 0 1 1 1 1 CCCH-type zinc finger Rho_RNA_bind PF07497.12 OQS07040.1 - 0.0042 16.9 0.0 0.0071 16.2 0.0 1.3 1 0 0 1 1 1 1 Rho termination factor, RNA-binding domain Torus PF16131.5 OQS07040.1 - 0.081 13.6 4.4 0.062 14.0 2.6 1.8 1 1 1 2 2 2 0 Torus domain zf-CCCH_3 PF15663.5 OQS07040.1 - 0.35 11.1 3.1 0.29 11.4 1.7 1.5 2 0 0 2 2 2 0 Zinc-finger containing family Cullin_binding PF03556.15 OQS07041.1 - 2.4e-33 115.1 1.6 4e-33 114.4 1.6 1.4 1 0 0 1 1 1 1 Cullin binding PI3_PI4_kinase PF00454.27 OQS07042.1 - 1.3e-26 94.0 0.0 1.1e-20 74.6 0.0 2.5 1 1 1 2 2 2 2 Phosphatidylinositol 3- and 4-kinase FYVE PF01363.21 OQS07042.1 - 0.00054 20.0 2.0 0.0011 19.1 2.0 1.4 1 0 0 1 1 1 1 FYVE zinc finger zf-AN1 PF01428.16 OQS07042.1 - 0.029 14.5 1.5 0.072 13.3 1.5 1.6 1 0 0 1 1 1 0 AN1-like Zinc finger PX PF00787.24 OQS07042.1 - 0.035 14.1 0.1 0.11 12.4 0.1 1.8 1 0 0 1 1 1 0 PX domain Ion_trans PF00520.31 OQS07043.1 - 1.1e-19 70.7 16.3 1.5e-19 70.2 16.3 1.2 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 OQS07043.1 - 8.5e-13 48.1 5.6 8.5e-13 48.1 5.6 2.4 3 1 0 3 3 3 1 Ion channel cNMP_binding PF00027.29 OQS07043.1 - 0.00014 21.9 0.0 0.00049 20.1 0.0 1.9 1 1 0 1 1 1 1 Cyclic nucleotide-binding domain Matrilin_ccoil PF10393.9 OQS07043.1 - 0.037 13.9 0.9 0.062 13.2 0.1 1.8 2 0 0 2 2 2 0 Trimeric coiled-coil oligomerisation domain of matrilin zf-CHY PF05495.12 OQS07044.1 - 1.1e-17 64.2 22.2 1.1e-17 64.2 22.2 3.0 2 1 0 2 2 2 1 CHY zinc finger zf-RING_2 PF13639.6 OQS07044.1 - 1.2e-09 38.4 9.0 1.2e-09 38.4 9.0 4.7 2 1 1 3 3 3 1 Ring finger domain zf-C3HC4 PF00097.25 OQS07044.1 - 0.00012 21.9 9.3 0.00012 21.9 9.3 4.4 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 OQS07044.1 - 0.00014 21.5 4.1 0.00014 21.5 4.1 4.5 4 1 0 4 4 4 1 RING-like zinc finger zf-RING_5 PF14634.6 OQS07044.1 - 0.00024 21.0 9.5 0.00024 21.0 9.5 5.6 3 3 1 4 4 4 1 zinc-RING finger domain zf-rbx1 PF12678.7 OQS07044.1 - 0.00038 20.7 7.5 0.00038 20.7 7.5 4.3 2 2 3 5 5 5 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 OQS07044.1 - 0.0012 18.8 5.8 0.0012 18.8 5.8 4.5 4 2 1 5 5 5 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 OQS07044.1 - 0.0015 18.3 8.4 0.0015 18.3 8.4 4.7 3 1 1 5 5 5 1 Zinc finger, C3HC4 type (RING finger) FYDLN_acid PF09538.10 OQS07044.1 - 0.012 16.3 9.7 0.012 16.3 9.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) KASH_CCD PF14662.6 OQS07045.1 - 3e-05 23.9 21.5 3e-05 23.9 21.5 8.1 2 2 4 7 7 7 3 Coiled-coil region of CCDC155 or KASH ABC_tran_CTD PF16326.5 OQS07045.1 - 0.0002 21.6 5.9 0.0002 21.6 5.9 15.9 3 3 10 16 16 15 2 ABC transporter C-terminal domain Filament PF00038.21 OQS07045.1 - 0.00024 20.8 39.3 0.00024 20.8 39.3 5.6 1 1 3 5 5 5 2 Intermediate filament protein TPR_MLP1_2 PF07926.12 OQS07045.1 - 0.0016 18.5 3.7 0.0016 18.5 3.7 11.9 2 2 10 12 12 12 5 TPR/MLP1/MLP2-like protein ATG16 PF08614.11 OQS07045.1 - 0.0057 16.9 23.8 0.0057 16.9 23.8 8.6 1 1 7 8 8 8 2 Autophagy protein 16 (ATG16) DUF4200 PF13863.6 OQS07045.1 - 0.014 15.8 3.2 0.014 15.8 3.2 10.7 2 1 6 9 9 7 0 Domain of unknown function (DUF4200) DUF4407 PF14362.6 OQS07045.1 - 0.48 9.7 123.5 0.75 9.1 14.3 8.2 1 1 6 7 7 7 0 Domain of unknown function (DUF4407) CALCOCO1 PF07888.11 OQS07045.1 - 0.53 9.1 147.4 0.11 11.4 29.8 5.1 1 1 4 5 5 4 0 Calcium binding and coiled-coil domain (CALCOCO1) like Spc7 PF08317.11 OQS07045.1 - 1.8 7.4 157.5 0.58 9.0 20.2 8.0 1 1 7 8 8 8 0 Spc7 kinetochore protein WD40_alt PF14077.6 OQS07045.1 - 3.1 7.8 6.0 56 3.7 0.2 4.7 4 0 0 4 4 4 0 Alternative WD40 repeat motif TIR-like PF10137.9 OQS07045.1 - 3.7 7.5 5.6 10 6.1 1.5 4.0 2 1 1 3 3 3 0 Predicted nucleotide-binding protein containing TIR-like domain Shugoshin_N PF07558.11 OQS07045.1 - 3.7 7.5 14.2 2.5 8.0 0.8 5.5 3 1 1 4 4 4 0 Shugoshin N-terminal coiled-coil region BHD_3 PF10405.9 OQS07046.1 - 5.6e-27 94.0 0.5 1.2e-26 93.0 0.5 1.6 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 3 BHD_1 PF10403.9 OQS07046.1 - 2.1e-12 46.6 0.1 4.5e-12 45.6 0.1 1.6 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 1 BHD_2 PF10404.9 OQS07046.1 - 2.7e-08 34.6 6.1 2e-07 31.9 6.1 2.3 1 1 0 1 1 1 1 Rad4 beta-hairpin domain 2 Rad4 PF03835.15 OQS07046.1 - 2.4e-05 24.0 0.0 4.4e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain ubiquitin PF00240.23 OQS07047.1 - 0.00099 18.8 0.0 0.0021 17.7 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family VKOR PF07884.14 OQS07047.1 - 0.0091 16.2 1.6 0.012 15.8 1.6 1.1 1 0 0 1 1 1 1 Vitamin K epoxide reductase family LAMTOR5 PF16672.5 OQS07048.1 - 0.0045 16.9 0.0 0.0045 16.9 0.0 1.3 1 1 0 1 1 1 1 Ragulator complex protein LAMTOR5 MRP-L27 PF09809.9 OQS07049.1 - 1.4e-15 57.1 0.1 1.6e-15 56.9 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L27 GBP_C PF02841.14 OQS07050.1 - 7.7e-24 84.6 31.7 8.8e-23 81.1 31.7 2.0 1 1 0 1 1 1 1 Guanylate-binding protein, C-terminal domain Filament PF00038.21 OQS07050.1 - 0.00018 21.2 12.0 0.00018 21.2 12.0 3.1 1 1 1 3 3 3 2 Intermediate filament protein CHASE6_C PF17150.4 OQS07050.1 - 1 10.1 8.8 1.3 9.7 0.2 3.3 2 1 1 3 3 3 0 C-terminal domain of two-partite extracellular sensor domain TMF_TATA_bd PF12325.8 OQS07050.1 - 2.7 8.2 27.6 0.88 9.8 3.8 3.7 2 1 1 3 3 3 0 TATA element modulatory factor 1 TATA binding DUF3450 PF11932.8 OQS07050.1 - 3.5 6.9 28.7 12 5.1 1.9 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF3450) CENP-F_leu_zip PF10473.9 OQS07050.1 - 3.8 7.5 37.7 0.43 10.6 21.3 3.6 2 2 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Kinesin_assoc PF16183.5 OQS07050.1 - 4.7 7.3 12.1 1.5 8.9 8.1 1.9 2 0 0 2 2 2 0 Kinesin-associated DUF1687 PF07955.11 OQS07050.1 - 6.5 7.2 8.2 9.4 6.7 2.9 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1687) FOXP-CC PF16159.5 OQS07050.1 - 7.2 7.3 8.9 2.3 8.9 3.1 3.0 2 0 0 2 2 2 0 FOXP coiled-coil domain DUF812 PF05667.11 OQS07050.1 - 7.4 5.3 32.1 14 4.4 20.7 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF812) UQ_con PF00179.26 OQS07051.1 - 3.3e-36 124.0 0.0 4.9e-36 123.5 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 OQS07051.1 - 0.029 14.7 0.0 0.035 14.4 0.0 1.3 1 0 0 1 1 1 0 RWD domain CLP_protease PF00574.23 OQS07052.1 - 3e-09 37.0 0.0 5.2e-09 36.2 0.0 1.4 1 0 0 1 1 1 1 Clp protease Peptidase_S24 PF00717.23 OQS07052.1 - 7.2e-09 35.5 0.0 1.6e-08 34.4 0.0 1.6 1 1 0 1 1 1 1 Peptidase S24-like Peptidase_S26 PF10502.9 OQS07052.1 - 9.4e-09 35.2 0.0 3.6e-07 30.0 0.0 2.6 1 1 0 2 2 2 1 Signal peptidase, peptidase S26 DUF2012 PF09430.10 OQS07053.1 - 2.9e-19 69.4 0.0 6.2e-19 68.3 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2012) DOT1 PF08123.13 OQS07053.1 - 2.4e-10 40.3 0.0 4.1e-10 39.5 0.0 1.3 1 0 0 1 1 1 1 Histone methylation protein DOT1 CarboxypepD_reg PF13620.6 OQS07053.1 - 3.1e-07 30.6 0.0 6.2e-07 29.6 0.0 1.5 1 0 0 1 1 1 1 Carboxypeptidase regulatory-like domain CarbopepD_reg_2 PF13715.6 OQS07053.1 - 0.0085 16.1 0.0 0.021 14.8 0.0 1.7 1 0 0 1 1 1 1 CarboxypepD_reg-like domain fn3_3 PF14686.6 OQS07053.1 - 0.0093 15.7 0.0 0.017 14.9 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide lyase family 4, domain II SdrD_B PF17210.3 OQS07053.1 - 0.098 12.9 0.0 0.2 11.9 0.0 1.4 1 0 0 1 1 1 0 SdrD B-like domain DUF2846 PF11008.8 OQS07053.1 - 0.1 12.6 0.0 0.79 9.8 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2846) YkyA PF10368.9 OQS07053.1 - 0.23 11.1 0.1 0.43 10.2 0.1 1.3 1 0 0 1 1 1 0 Putative cell-wall binding lipoprotein MIP-T3 PF10243.9 OQS07054.1 - 2.5e-81 269.0 7.5 3.1e-40 136.7 0.1 2.9 3 0 0 3 3 3 2 Microtubule-binding protein MIP-T3 CH-like domain MIP-T3_C PF17749.1 OQS07054.1 - 7.9e-35 120.1 9.6 7.9e-35 120.1 9.6 3.6 2 1 0 2 2 2 1 Microtubule-binding protein MIP-T3 C-terminal region COMP PF11598.8 OQS07054.1 - 8.9 6.9 9.0 0.48 10.9 0.6 3.0 3 0 0 3 3 3 0 Cartilage oligomeric matrix protein NHL PF01436.21 OQS07055.1 - 7e-11 41.6 1.8 0.00059 19.7 0.0 5.1 5 0 0 5 5 5 3 NHL repeat SGL PF08450.12 OQS07055.1 - 0.00023 20.8 0.5 0.043 13.4 0.1 2.6 1 1 0 2 2 2 2 SMP-30/Gluconolactonase/LRE-like region Arylesterase PF01731.20 OQS07055.1 - 0.0018 18.4 0.9 2 8.6 0.0 3.5 2 1 1 3 3 3 1 Arylesterase SBBP PF06739.11 OQS07055.1 - 0.04 13.9 0.2 0.04 13.9 0.2 4.7 5 0 0 5 5 5 0 Beta-propeller repeat Dmrt1 PF12374.8 OQS07055.1 - 0.059 13.8 1.7 0.17 12.3 1.7 1.8 1 0 0 1 1 1 0 Double-sex mab3 related transcription factor 1 AFG1_ATPase PF03969.16 OQS07056.1 - 1.8e-99 333.1 1.0 2.3e-99 332.7 1.0 1.1 1 0 0 1 1 1 1 AFG1-like ATPase AAA_14 PF13173.6 OQS07056.1 - 9.8e-05 22.4 0.0 0.00033 20.7 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 OQS07056.1 - 0.00027 21.4 0.1 0.024 15.1 0.0 2.9 3 1 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) Bac_DnaA PF00308.18 OQS07056.1 - 0.0014 18.5 2.0 0.0032 17.4 0.0 2.6 3 1 1 4 4 4 1 Bacterial dnaA protein AAA_16 PF13191.6 OQS07056.1 - 0.0018 18.6 0.1 0.46 10.9 0.0 2.7 1 1 1 2 2 2 1 AAA ATPase domain EF-hand_7 PF13499.6 OQS07056.1 - 0.0024 18.3 0.6 0.01 16.3 0.1 2.4 2 0 0 2 2 2 1 EF-hand domain pair ATPase_2 PF01637.18 OQS07056.1 - 0.0032 17.4 1.0 0.032 14.1 0.0 2.8 3 0 0 3 3 3 1 ATPase domain predominantly from Archaea AAA_22 PF13401.6 OQS07056.1 - 0.0087 16.3 0.4 0.087 13.1 0.0 2.9 2 1 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 OQS07056.1 - 0.034 13.4 0.0 0.15 11.3 0.0 1.9 2 0 0 2 2 2 0 Zeta toxin TsaE PF02367.17 OQS07056.1 - 0.034 14.1 0.0 0.082 12.9 0.0 1.7 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Pex19 PF04614.12 OQS07056.1 - 0.04 13.7 1.2 0.091 12.5 1.2 1.6 1 0 0 1 1 1 0 Pex19 protein family WWE PF02825.20 OQS07056.1 - 0.084 13.5 0.4 0.28 11.8 0.1 2.2 2 0 0 2 2 2 0 WWE domain AAA_7 PF12775.7 OQS07056.1 - 0.085 12.4 0.2 0.63 9.5 0.0 2.2 2 0 0 2 2 2 0 P-loop containing dynein motor region UvrD-helicase PF00580.21 OQS07056.1 - 0.18 11.3 1.2 3.7 7.0 0.0 2.6 2 1 1 3 3 3 0 UvrD/REP helicase N-terminal domain FIBP PF05427.11 OQS07057.1 - 2.1e-70 237.8 2.9 3.2e-57 194.5 0.4 2.3 2 0 0 2 2 2 2 Acidic fibroblast growth factor binding (FIBP) EF-hand_6 PF13405.6 OQS07057.1 - 2e-15 55.3 6.3 0.0011 18.7 0.4 5.3 5 0 0 5 5 5 4 EF-hand domain EF-hand_7 PF13499.6 OQS07057.1 - 1.5e-14 54.2 6.9 4.2e-10 39.9 2.6 3.2 2 0 0 2 2 2 2 EF-hand domain pair Rsa3 PF14615.6 OQS07057.1 - 6.8e-14 51.2 0.2 2e-13 49.7 0.2 1.9 1 0 0 1 1 1 1 Ribosome-assembly protein 3 EF-hand_1 PF00036.32 OQS07057.1 - 2.5e-13 48.5 8.0 0.00071 19.0 0.4 4.9 4 0 0 4 4 4 4 EF hand DMRL_synthase PF00885.19 OQS07057.1 - 1.1e-10 41.5 0.2 3.6e-10 39.8 0.2 1.9 1 0 0 1 1 1 1 6,7-dimethyl-8-ribityllumazine synthase EF-hand_8 PF13833.6 OQS07057.1 - 8.7e-10 38.3 8.5 6e-08 32.4 2.1 4.4 3 1 1 4 4 4 1 EF-hand domain pair EF-hand_5 PF13202.6 OQS07057.1 - 8.9e-07 28.1 9.9 0.013 15.0 0.3 4.8 4 0 0 4 4 4 2 EF hand EF-hand_11 PF08976.11 OQS07057.1 - 0.13 13.1 0.2 0.7 10.8 0.0 2.3 3 0 0 3 3 3 0 EF-hand domain AMP-binding PF00501.28 OQS07058.1 - 5e-84 282.4 0.0 6.7e-84 281.9 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Thump_like PF18096.1 OQS07058.1 - 0.024 14.6 0.0 0.12 12.4 0.0 2.0 2 0 0 2 2 2 0 THUMP domain-like NAD_synthase PF02540.17 OQS07059.1 - 1.3e-07 31.0 0.0 3.2e-07 29.7 0.0 1.6 1 1 0 1 1 1 1 NAD synthase tRNA_Me_trans PF03054.16 OQS07059.1 - 5.9e-06 25.3 0.0 0.0034 16.2 0.0 2.3 2 0 0 2 2 2 2 tRNA methyl transferase QueC PF06508.13 OQS07059.1 - 4.8e-05 22.9 0.2 0.17 11.4 0.0 2.8 2 1 1 3 3 3 2 Queuosine biosynthesis protein QueC Asn_synthase PF00733.21 OQS07059.1 - 0.00018 21.3 0.0 0.00022 21.0 0.0 1.4 1 1 0 1 1 1 1 Asparagine synthase ATP_bind_3 PF01171.20 OQS07059.1 - 0.11 12.3 0.1 0.33 10.7 0.1 1.7 2 0 0 2 2 2 0 PP-loop family Glutaredoxin PF00462.24 OQS07060.1 - 3.5e-12 46.4 2.7 6.7e-12 45.5 2.7 1.5 1 0 0 1 1 1 1 Glutaredoxin GST_N_3 PF13417.6 OQS07060.1 - 7.8e-11 42.2 0.1 1.3e-10 41.5 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 OQS07060.1 - 3e-07 30.7 0.1 5.8e-07 29.7 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_6 PF17171.4 OQS07060.1 - 0.00019 21.1 0.0 0.00049 19.8 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 OQS07060.1 - 0.00025 21.3 0.0 0.00069 19.9 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 OQS07060.1 - 0.00047 20.1 0.0 0.0011 19.0 0.0 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 OQS07060.1 - 0.023 15.4 0.0 0.082 13.7 0.0 1.9 2 0 0 2 2 2 0 Glutathione S-transferase N-terminal domain Thioredoxin_3 PF13192.6 OQS07060.1 - 0.045 13.8 1.9 0.11 12.6 1.9 1.5 1 0 0 1 1 1 0 Thioredoxin domain GST_C PF00043.25 OQS07060.1 - 0.057 13.6 0.0 0.12 12.7 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Glyco_hydro_6 PF01341.17 OQS07061.1 - 1.8e-50 172.4 0.0 2.5e-50 172.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 6 Senescence PF06911.12 OQS07061.1 - 0.07 13.4 0.0 0.23 11.7 0.0 1.8 2 0 0 2 2 2 0 Senescence-associated protein Perilipin PF03036.16 OQS07061.1 - 0.44 9.5 0.8 0.67 8.9 0.8 1.1 1 0 0 1 1 1 0 Perilipin family His_Phos_2 PF00328.22 OQS07062.1 - 2.1e-17 63.6 0.1 6.3e-16 58.7 0.1 2.2 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Transket_pyr PF02779.24 OQS07064.1 - 1.3e-62 210.6 0.0 1.9e-62 210.1 0.0 1.2 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain E1_dh PF00676.20 OQS07064.1 - 7.2e-60 202.5 0.0 1.1e-59 201.9 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component OxoGdeHyase_C PF16870.5 OQS07064.1 - 5.4e-55 185.3 0.0 9.4e-55 184.5 0.0 1.4 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase C-terminal 2-oxogl_dehyd_N PF16078.5 OQS07064.1 - 1.5e-18 66.1 0.3 3.3e-18 65.0 0.3 1.6 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase N-terminus R2K_2 PF18299.1 OQS07064.1 - 0.029 14.2 0.0 0.061 13.2 0.0 1.4 1 0 0 1 1 1 0 ATP-grasp domain, R2K clade family 2 Fumble PF03630.14 OQS07065.1 - 3.5e-119 397.8 1.3 3.5e-119 397.8 1.3 2.8 3 1 0 3 3 3 1 Fumble Cnn_1N PF07989.11 OQS07065.1 - 5.1e-10 39.4 5.0 5.1e-10 39.4 5.0 10.5 8 3 1 9 9 9 2 Centrosomin N-terminal motif 1 DUF4094 PF13334.6 OQS07065.1 - 0.03 14.8 0.6 0.03 14.8 0.6 7.0 4 2 2 6 6 6 0 Domain of unknown function (DUF4094) TTL PF03133.15 OQS07066.1 - 1.3e-101 339.6 0.6 2.2e-101 338.9 0.6 1.3 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family Myb_DNA-binding PF00249.31 OQS07066.1 - 2.9e-26 91.4 3.6 1.2e-12 47.8 0.1 2.9 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OQS07066.1 - 4.3e-20 71.7 0.2 3.1e-13 49.8 0.0 2.8 1 1 1 2 2 2 2 Myb-like DNA-binding domain ATPgrasp_YheCD PF14398.6 OQS07066.1 - 2.6e-07 30.2 0.0 9e-05 21.8 0.0 2.5 2 0 0 2 2 2 2 YheC/D like ATP-grasp Myb_DNA-bind_7 PF15963.5 OQS07066.1 - 3.8e-07 29.9 0.7 0.00031 20.6 0.6 3.3 2 1 1 3 3 3 2 Myb DNA-binding like ATPgrasp_ST PF14397.6 OQS07066.1 - 0.00018 20.9 0.0 0.012 14.9 0.0 2.2 2 0 0 2 2 2 1 Sugar-transfer associated ATP-grasp N2227 PF07942.12 OQS07067.1 - 1.6e-80 270.2 0.0 3.1e-80 269.3 0.0 1.4 1 0 0 1 1 1 1 N2227-like protein Rad21_Rec8_N PF04825.13 OQS07067.1 - 1.1e-33 115.7 0.0 2.4e-33 114.6 0.0 1.6 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.16 OQS07067.1 - 1.3e-11 43.6 0.2 3e-11 42.4 0.2 1.7 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein EF-hand_6 PF13405.6 OQS07067.1 - 4.8e-11 41.7 13.0 0.032 14.2 0.5 8.2 7 0 0 7 7 7 2 EF-hand domain EF-hand_7 PF13499.6 OQS07067.1 - 8.4e-08 32.6 6.8 0.74 10.3 0.1 7.7 7 0 0 7 7 7 1 EF-hand domain pair EF-hand_1 PF00036.32 OQS07067.1 - 1.4e-07 30.5 8.8 0.039 13.5 0.1 7.3 7 0 0 7 7 7 2 EF hand DUF5580 PF17743.1 OQS07067.1 - 0.00018 20.2 0.0 0.00035 19.2 0.0 1.4 1 0 0 1 1 1 1 Family of unknown function (DUF5580) Methyltransf_23 PF13489.6 OQS07067.1 - 0.0025 17.7 0.0 0.013 15.3 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain EF-hand_5 PF13202.6 OQS07067.1 - 0.013 15.0 1.1 0.1 12.2 0.3 3.0 2 0 0 2 2 2 0 EF hand Methyltransf_12 PF08242.12 OQS07067.1 - 0.036 14.8 0.0 0.21 12.3 0.0 2.4 1 0 0 1 1 1 0 Methyltransferase domain RST PF12174.8 OQS07067.1 - 0.072 13.0 9.8 0.42 10.6 0.1 5.6 6 0 0 6 6 6 0 RCD1-SRO-TAF4 (RST) plant domain SMC_ScpA PF02616.14 OQS07067.1 - 0.14 12.0 0.6 1 9.2 0.0 2.6 2 0 0 2 2 2 0 Segregation and condensation protein ScpA CSTF_C PF14304.6 OQS07068.1 - 0.0026 17.3 11.0 0.0062 16.1 4.1 2.6 2 0 0 2 2 2 2 Transcription termination and cleavage factor C-terminal ATPgrasp_N PF18130.1 OQS07068.1 - 0.16 12.5 0.0 0.36 11.4 0.0 1.5 1 0 0 1 1 1 0 ATP-grasp N-terminal domain FYVE PF01363.21 OQS07069.1 - 9.6e-08 32.1 13.6 2.2e-07 30.9 13.6 1.6 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.16 OQS07069.1 - 0.022 15.0 7.4 0.046 13.9 7.4 1.5 1 0 0 1 1 1 0 FYVE-type zinc finger C1_2 PF03107.16 OQS07069.1 - 0.03 14.7 11.2 0.03 14.7 11.2 2.3 2 0 0 2 2 2 0 C1 domain DUF3337 PF11816.8 OQS07069.1 - 0.038 13.9 0.0 0.059 13.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3337) zf-B_box PF00643.24 OQS07069.1 - 3.6 7.8 14.1 0.32 11.2 7.3 2.5 2 1 0 2 2 2 0 B-box zinc finger AMP-binding PF00501.28 OQS07070.1 - 8.9e-85 284.8 0.0 1.1e-84 284.5 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme Cas_Cas2CT1978 PF09707.10 OQS07070.1 - 2.1e-06 27.7 0.0 4.8e-05 23.4 0.0 2.7 2 0 0 2 2 2 1 CRISPR-associated protein (Cas_Cas2CT1978) F_actin_cap_B PF01115.17 OQS07072.1 - 1.7e-96 322.5 0.0 3e-96 321.7 0.0 1.4 1 0 0 1 1 1 1 F-actin capping protein, beta subunit GATase_5 PF13507.6 OQS07072.1 - 1.6e-91 306.1 0.0 2.4e-91 305.5 0.0 1.3 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain Pkinase_Tyr PF07714.17 OQS07072.1 - 3.7e-42 144.4 0.0 6.3e-42 143.6 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OQS07072.1 - 1.2e-40 139.6 0.0 2.4e-40 138.6 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain AIRS_C PF02769.22 OQS07072.1 - 1.5e-32 112.9 0.8 8.3e-19 68.2 0.1 2.4 2 0 0 2 2 2 2 AIR synthase related protein, C-terminal domain FGAR-AT_N PF18076.1 OQS07072.1 - 3.1e-20 72.3 0.0 6.2e-20 71.3 0.0 1.5 1 0 0 1 1 1 1 Formylglycinamide ribonucleotide amidotransferase N-terminal LRR_8 PF13855.6 OQS07072.1 - 2.2e-14 53.0 29.2 5.3e-06 26.1 3.7 5.1 3 1 2 5 5 5 4 Leucine rich repeat LRR_4 PF12799.7 OQS07072.1 - 6.4e-13 48.7 30.9 7.5e-05 23.0 2.0 5.9 4 1 1 5 5 5 5 Leucine Rich repeats (2 copies) FGAR-AT_linker PF18072.1 OQS07072.1 - 1.3e-10 41.6 0.1 1.3e-09 38.4 0.0 2.6 2 0 0 2 2 2 1 Formylglycinamide ribonucleotide amidotransferase linker domain AIRS PF00586.24 OQS07072.1 - 0.02 15.5 0.9 0.22 12.2 0.0 2.7 2 0 0 2 2 2 0 AIR synthase related protein, N-terminal domain LRR_6 PF13516.6 OQS07072.1 - 0.31 11.2 16.3 5.6 7.3 0.1 6.4 6 0 0 6 6 6 0 Leucine Rich repeat LRR_1 PF00560.33 OQS07072.1 - 0.86 10.4 18.4 10 7.1 0.2 7.1 6 1 0 6 6 6 0 Leucine Rich Repeat FNIP PF05725.12 OQS07072.1 - 6 7.1 12.1 2.5 8.4 0.5 3.8 2 1 1 3 3 3 0 FNIP Repeat Acyl-CoA_dh_1 PF00441.24 OQS07073.1 - 3e-34 118.4 0.6 5e-34 117.7 0.6 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 OQS07073.1 - 2.9e-32 111.7 0.0 5.7e-32 110.7 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 OQS07073.1 - 6.2e-22 77.6 0.1 1.1e-21 76.8 0.1 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 OQS07073.1 - 1.6e-14 54.4 0.0 3.2e-14 53.4 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_ox_N PF14749.6 OQS07073.1 - 0.042 14.4 0.0 0.078 13.5 0.0 1.4 1 0 0 1 1 1 0 Acyl-coenzyme A oxidase N-terminal Helicase_C PF00271.31 OQS07075.1 - 1.7e-18 67.0 0.0 3.9e-18 65.8 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 OQS07075.1 - 7.6e-06 25.8 0.0 2.4e-05 24.2 0.0 1.9 1 0 0 1 1 1 1 DEAD/DEAH box helicase HA2 PF04408.23 OQS07075.1 - 1.8e-05 25.0 0.2 4.8e-05 23.6 0.0 1.8 2 0 0 2 2 2 1 Helicase associated domain (HA2) XPG_I PF00867.18 OQS07075.1 - 3.3e-05 24.1 0.1 0.00019 21.7 0.0 2.5 2 0 0 2 2 2 1 XPG I-region AAA_22 PF13401.6 OQS07075.1 - 0.0011 19.2 0.0 0.0065 16.7 0.0 2.2 2 0 0 2 2 2 1 AAA domain YlbD_coat PF14071.6 OQS07075.1 - 0.0027 17.9 0.2 0.58 10.4 0.1 2.8 2 0 0 2 2 2 1 Putative coat protein XPG_I_2 PF12813.7 OQS07075.1 - 0.0091 15.5 0.0 0.02 14.3 0.0 1.5 1 0 0 1 1 1 1 XPG domain containing ATPase PF06745.13 OQS07075.1 - 0.019 14.3 0.0 0.038 13.3 0.0 1.4 1 0 0 1 1 1 0 KaiC ABC_tran PF00005.27 OQS07075.1 - 0.088 13.3 0.0 0.29 11.6 0.0 1.9 1 0 0 1 1 1 0 ABC transporter AAA_23 PF13476.6 OQS07075.1 - 0.22 12.0 1.6 0.81 10.2 0.2 2.5 2 0 0 2 2 2 0 AAA domain XRN_M PF17846.1 OQS07076.1 - 5.9e-150 500.1 0.0 1.9e-149 498.4 0.0 1.8 2 0 0 2 2 2 1 Xrn1 helical domain XRN_N PF03159.18 OQS07076.1 - 1.2e-96 322.8 0.0 2.1e-96 322.0 0.0 1.4 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus Acylphosphatase PF00708.18 OQS07077.1 - 6.2e-13 49.0 0.4 7.5e-13 48.7 0.4 1.2 1 0 0 1 1 1 1 Acylphosphatase SET PF00856.28 OQS07078.1 - 8.5e-10 39.3 0.1 1.5e-07 31.9 0.0 2.1 1 1 1 2 2 2 2 SET domain zf-MYND PF01753.18 OQS07078.1 - 1.2e-07 31.7 11.8 1.2e-07 31.7 11.8 2.2 3 0 0 3 3 3 1 MYND finger LRR_6 PF13516.6 OQS07079.1 - 2.3e-16 58.4 20.6 0.0058 16.6 0.1 7.7 7 0 0 7 7 7 7 Leucine Rich repeat LRR_1 PF00560.33 OQS07079.1 - 9.7e-06 25.5 17.7 1.1 10.1 0.1 7.6 7 0 0 7 7 7 2 Leucine Rich Repeat LRR_8 PF13855.6 OQS07079.1 - 5.7e-05 22.8 27.6 0.032 14.0 0.9 6.5 1 1 3 6 6 6 5 Leucine rich repeat LRR_4 PF12799.7 OQS07079.1 - 8.8e-05 22.8 21.3 0.18 12.3 3.6 5.2 5 0 0 5 5 5 3 Leucine Rich repeats (2 copies) Pyr_redox_2 PF07992.14 OQS07080.1 - 6.3e-21 74.9 0.0 8.9e-21 74.4 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase AIF_C PF14721.6 OQS07080.1 - 9e-18 64.9 0.1 9.4e-08 32.5 0.0 2.4 1 1 1 2 2 2 2 Apoptosis-inducing factor, mitochondrion-associated, C-term Pyr_redox PF00070.27 OQS07080.1 - 1.5e-06 28.6 0.0 3.3e-06 27.6 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 OQS07080.1 - 0.021 14.0 1.9 1.1 8.3 0.0 3.4 3 1 1 4 4 4 0 L-lysine 6-monooxygenase (NADPH-requiring) GMP_PDE_delta PF05351.11 OQS07081.1 - 6.2e-61 205.1 0.8 8.4e-61 204.6 0.8 1.2 1 0 0 1 1 1 1 GMP-PDE, delta subunit Ank_2 PF12796.7 OQS07082.1 - 1.8e-26 92.5 0.2 6.7e-12 45.8 0.1 3.6 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQS07082.1 - 1.4e-21 76.6 3.5 4.4e-07 30.3 0.2 4.8 5 0 0 5 5 4 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 OQS07082.1 - 4.9e-15 55.4 0.6 3.1e-06 27.3 0.0 4.4 4 1 1 5 5 5 3 Ankyrin repeats (many copies) WW PF00397.26 OQS07082.1 - 6.8e-15 54.9 6.2 1.1e-06 28.7 0.9 2.6 2 0 0 2 2 2 2 WW domain Ank PF00023.30 OQS07082.1 - 8.5e-15 54.5 1.9 0.072 13.6 0.1 6.5 6 0 0 6 6 6 4 Ankyrin repeat Ank_3 PF13606.6 OQS07082.1 - 1.5e-12 46.5 3.5 0.24 12.1 0.0 6.7 6 0 0 6 6 6 3 Ankyrin repeat Glyco_hyd_101C PF17451.2 OQS07082.1 - 0.013 15.8 2.2 6.4 7.1 0.2 3.3 3 0 0 3 3 3 0 Glycosyl hydrolase 101 beta sandwich domain Polysacc_deac_1 PF01522.21 OQS07082.1 - 0.039 13.9 1.9 0.055 13.4 0.4 2.0 2 0 0 2 2 2 0 Polysaccharide deacetylase BTRD1 PF17660.1 OQS07082.1 - 0.16 11.8 0.0 3.1 7.7 0.0 2.5 2 0 0 2 2 2 0 Bacterial tandem repeat domain 1 TipAS PF07739.13 OQS07082.1 - 1.9 9.1 8.1 68 4.0 7.3 2.6 2 0 0 2 2 2 0 TipAS antibiotic-recognition domain 5_nucleotid PF05761.14 OQS07082.1 - 5.5 5.8 6.5 11 4.8 6.5 1.4 1 0 0 1 1 1 0 5' nucleotidase family DUF5466 PF17554.2 OQS07083.1 - 0.039 14.2 3.4 4.1 7.7 0.1 2.9 2 0 0 2 2 2 0 Family of unknown function (DUF5466) Methyltransf_15 PF09445.10 OQS07084.1 - 2.3e-16 59.8 0.1 3.9e-16 59.0 0.1 1.3 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase DUF3987 PF13148.6 OQS07084.1 - 0.05 12.6 0.1 0.07 12.1 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) Cons_hypoth95 PF03602.15 OQS07084.1 - 0.13 11.9 0.8 0.98 9.0 0.0 2.3 2 1 0 2 2 2 0 Conserved hypothetical protein 95 Pkinase PF00069.25 OQS07085.1 - 6e-62 209.4 0.0 1.3e-61 208.3 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain AAA_2 PF07724.14 OQS07085.1 - 3.7e-50 170.4 0.0 3.1e-48 164.1 0.0 2.6 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) Pkinase_Tyr PF07714.17 OQS07085.1 - 3.3e-43 147.8 0.0 7.5e-43 146.7 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase AAA_lid_9 PF17871.1 OQS07085.1 - 3.7e-32 110.3 4.2 3.7e-32 110.3 4.2 2.7 2 0 0 2 2 2 1 AAA lid domain AAA PF00004.29 OQS07085.1 - 1.1e-21 77.6 0.0 1.6e-12 48.0 0.0 2.9 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.9 OQS07085.1 - 2.4e-17 62.7 0.1 1e-16 60.7 0.1 2.2 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.14 OQS07085.1 - 2e-15 57.0 0.0 7.3e-10 39.0 0.0 3.4 3 0 0 3 3 3 2 AAA domain (dynein-related subfamily) FYVE PF01363.21 OQS07085.1 - 7.2e-14 51.7 11.0 1.5e-13 50.7 11.0 1.6 1 0 0 1 1 1 1 FYVE zinc finger AAA_16 PF13191.6 OQS07085.1 - 6.5e-09 36.4 1.7 9.7e-05 22.8 0.1 4.5 2 2 0 3 3 3 2 AAA ATPase domain AAA_22 PF13401.6 OQS07085.1 - 2e-07 31.3 1.4 0.0087 16.3 0.0 4.7 3 1 0 3 3 3 1 AAA domain Kinase-like PF14531.6 OQS07085.1 - 2e-06 27.3 0.0 0.00046 19.6 0.0 2.8 2 0 0 2 2 2 1 Kinase-like AAA_23 PF13476.6 OQS07085.1 - 2.8e-05 24.7 7.3 0.0033 18.0 0.0 3.6 2 1 0 2 2 2 1 AAA domain Codanin-1_C PF15296.6 OQS07085.1 - 3.7e-05 23.8 0.0 0.00015 21.8 0.0 2.1 1 0 0 1 1 1 1 Codanin-1 C-terminus Pkinase_fungal PF17667.1 OQS07085.1 - 4.3e-05 22.5 0.0 0.00017 20.5 0.0 2.0 2 0 0 2 2 2 1 Fungal protein kinase IstB_IS21 PF01695.17 OQS07085.1 - 6.1e-05 22.8 0.0 0.14 11.9 0.0 2.7 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_7 PF12775.7 OQS07085.1 - 9.5e-05 22.0 0.0 0.33 10.5 0.0 2.9 2 0 0 2 2 2 2 P-loop containing dynein motor region Mg_chelatase PF01078.21 OQS07085.1 - 0.00012 21.6 0.0 0.39 10.1 0.0 2.6 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.26 OQS07085.1 - 0.00014 21.6 0.0 0.6 9.8 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_18 PF13238.6 OQS07085.1 - 0.0011 19.5 0.0 3.3 8.2 0.0 3.9 3 0 0 3 3 2 1 AAA domain NACHT PF05729.12 OQS07085.1 - 0.0013 18.7 0.0 0.062 13.2 0.0 3.1 2 0 0 2 2 2 1 NACHT domain RNA_helicase PF00910.22 OQS07085.1 - 0.0015 18.9 0.0 4 7.9 0.0 3.0 2 0 0 2 2 2 1 RNA helicase AAA_25 PF13481.6 OQS07085.1 - 0.002 17.7 0.2 0.055 13.0 0.0 2.9 2 0 0 2 2 2 1 AAA domain ATPase_2 PF01637.18 OQS07085.1 - 0.003 17.5 0.2 4.3 7.2 0.1 3.8 3 1 1 4 4 3 1 ATPase domain predominantly from Archaea Kdo PF06293.14 OQS07085.1 - 0.0037 16.6 0.1 0.012 14.9 0.0 1.9 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family RuvB_N PF05496.12 OQS07085.1 - 0.0065 16.2 0.4 7.5 6.3 0.4 3.2 2 1 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain TsaE PF02367.17 OQS07085.1 - 0.0069 16.4 0.0 5.7 7.0 0.0 2.6 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Roc PF08477.13 OQS07085.1 - 0.0092 16.2 0.0 6 7.1 0.0 2.8 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase RsgA_GTPase PF03193.16 OQS07085.1 - 0.01 15.7 0.0 5.5 6.9 0.0 3.0 2 0 0 2 2 2 0 RsgA GTPase AAA_33 PF13671.6 OQS07085.1 - 0.049 13.8 0.0 17 5.6 0.0 3.1 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 OQS07085.1 - 0.057 13.1 0.0 8.9 6.0 0.0 2.5 2 0 0 2 2 2 0 AAA domain TIP49 PF06068.13 OQS07085.1 - 0.06 12.5 0.5 3.9 6.6 0.0 2.9 3 0 0 3 3 3 0 TIP49 P-loop domain Tox-HNH-HHH PF15637.6 OQS07085.1 - 0.12 12.6 0.2 0.49 10.6 0.2 2.0 1 0 0 1 1 1 0 HNH/Endo VII superfamily nuclease toxin with a HHH motif AAA_28 PF13521.6 OQS07085.1 - 0.26 11.5 1.5 13 6.0 0.0 3.5 3 0 0 3 3 2 0 AAA domain FYVE_2 PF02318.16 OQS07085.1 - 0.66 10.2 5.3 1.6 8.9 3.7 2.6 2 0 0 2 2 1 0 FYVE-type zinc finger VPS13 PF16908.5 OQS07086.1 - 2.9e-30 105.8 0.0 1.1e-29 104.0 0.0 1.9 2 0 0 2 2 2 1 Vacuolar sorting-associated protein 13, N-terminal Chorein_N PF12624.7 OQS07086.1 - 2.6e-21 75.9 0.5 6.6e-21 74.6 0.5 1.7 1 0 0 1 1 1 1 N-terminal region of Chorein or VPS13 NumbF PF06311.12 OQS07086.1 - 0.031 14.8 0.0 0.12 12.9 0.0 2.0 1 0 0 1 1 1 0 NUMB domain Defensin_int PF17858.1 OQS07087.1 - 7.2 6.7 6.8 14 5.8 3.6 2.6 2 0 0 2 2 2 0 Platypus intermediate defensin-like peptide p450 PF00067.22 OQS07088.1 - 6.7e-06 25.1 0.0 2.4e-05 23.3 0.0 1.7 1 1 0 1 1 1 1 Cytochrome P450 Ldh_1_N PF00056.23 OQS07089.1 - 5e-34 117.4 0.2 7.6e-34 116.8 0.2 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.18 OQS07089.1 - 5.1e-25 88.3 0.0 7.7e-25 87.8 0.0 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Glyco_hydro_3_C PF01915.22 OQS07089.1 - 0.019 14.9 0.0 0.041 13.8 0.0 1.6 2 0 0 2 2 2 0 Glycosyl hydrolase family 3 C-terminal domain GMC_oxred_N PF00732.19 OQS07090.1 - 7.7e-51 173.2 0.0 1.4e-50 172.3 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 OQS07090.1 - 7.9e-26 91.3 1.1 1.4e-25 90.5 0.1 1.9 2 0 0 2 2 2 1 GMC oxidoreductase FAD_binding_2 PF00890.24 OQS07090.1 - 3.5e-07 29.7 3.6 4.1e-06 26.2 1.4 2.3 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.6 OQS07090.1 - 1.2e-05 25.4 2.0 3.2e-05 24.1 2.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 OQS07090.1 - 2.3e-05 23.8 0.6 0.00026 20.3 0.1 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 OQS07090.1 - 9.5e-05 22.1 8.6 0.003 17.2 8.4 2.6 2 1 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 OQS07090.1 - 0.00029 20.2 1.5 0.00047 19.5 1.0 1.6 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.14 OQS07090.1 - 0.0026 16.5 0.7 0.0048 15.7 0.7 1.4 1 0 0 1 1 1 1 HI0933-like protein ApbA PF02558.16 OQS07090.1 - 0.0054 16.4 0.1 0.011 15.4 0.1 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Abhydrolase_3 PF07859.13 OQS07090.1 - 0.011 15.5 0.0 0.022 14.6 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold Thi4 PF01946.17 OQS07090.1 - 0.014 14.7 0.4 0.014 14.7 0.4 2.8 4 0 0 4 4 4 0 Thi4 family Lycopene_cycl PF05834.12 OQS07090.1 - 0.048 12.7 0.0 0.08 12.0 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein Pyr_redox_3 PF13738.6 OQS07090.1 - 0.056 12.7 0.6 0.12 11.6 0.6 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 OQS07090.1 - 0.15 11.4 2.6 0.27 10.6 2.6 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase GDI PF00996.18 OQS07090.1 - 0.18 10.3 0.1 0.29 9.6 0.1 1.2 1 0 0 1 1 1 0 GDP dissociation inhibitor Pkinase PF00069.25 OQS07091.1 - 4.7e-52 177.0 0.0 7.8e-52 176.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQS07091.1 - 6.8e-51 173.0 0.0 1e-50 172.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase p450 PF00067.22 OQS07091.1 - 1.8e-24 86.4 0.0 3.2e-24 85.5 0.0 1.4 1 0 0 1 1 1 1 Cytochrome P450 Lipoxygenase PF00305.19 OQS07091.1 - 2.3e-17 62.7 0.6 6e-17 61.3 0.1 1.8 2 0 0 2 2 2 1 Lipoxygenase Pkinase_fungal PF17667.1 OQS07091.1 - 2e-05 23.6 0.0 3.3e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 OQS07091.1 - 0.017 14.5 0.0 0.032 13.6 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 OQS07091.1 - 0.019 14.3 0.0 0.042 13.2 0.0 1.5 1 0 0 1 1 1 0 Kinase-like MGC-24 PF05283.11 OQS07091.1 - 0.043 14.3 0.2 0.086 13.3 0.2 1.6 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin Beta-APP PF03494.13 OQS07091.1 - 0.34 10.8 2.2 0.82 9.6 2.2 1.6 1 0 0 1 1 1 0 Beta-amyloid peptide (beta-APP) Syndecan PF01034.20 OQS07091.1 - 6.2 6.8 5.4 1.6 8.7 1.4 2.0 2 0 0 2 2 2 0 Syndecan domain FAM183 PF14886.6 OQS07092.1 - 4.1e-06 27.5 0.4 6.8e-06 26.8 0.4 1.5 1 0 0 1 1 1 1 FAM183A and FAM183B related DUF5481 PF17578.2 OQS07092.1 - 0.0032 17.9 0.0 0.0046 17.3 0.0 1.4 1 0 0 1 1 1 1 Family of unknown function (DUF5481) p450 PF00067.22 OQS07093.1 - 5.4e-23 81.5 0.0 1.1e-22 80.4 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 HA PF03457.14 OQS07094.1 - 1.3e-24 86.2 0.4 3.4e-11 43.3 0.2 2.2 2 0 0 2 2 2 2 Helicase associated domain Peptidase_C14 PF00656.22 OQS07095.1 - 1.7e-55 188.7 0.0 2.3e-55 188.2 0.0 1.1 1 0 0 1 1 1 1 Caspase domain AMMECR1 PF01871.17 OQS07095.1 - 0.13 11.9 0.0 0.23 11.1 0.0 1.3 1 0 0 1 1 1 0 AMMECR1 Ank PF00023.30 OQS07096.1 - 8.5e-17 60.8 0.8 3.5e-07 30.4 0.0 3.1 4 0 0 4 4 4 2 Ankyrin repeat Ank_2 PF12796.7 OQS07096.1 - 1.1e-16 61.2 0.0 5.5e-08 33.3 0.0 2.5 2 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQS07096.1 - 9.3e-14 51.6 0.1 4.1e-06 27.2 0.0 3.2 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQS07096.1 - 8.6e-13 47.2 0.0 1.9e-05 24.6 0.0 3.3 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 OQS07096.1 - 2.3e-11 43.7 0.0 1.1e-05 25.6 0.0 2.3 2 0 0 2 2 2 2 Ankyrin repeats (many copies) HEAT PF02985.22 OQS07098.1 - 2.8e-16 58.2 9.6 2.6e-05 24.1 0.0 9.1 9 0 0 9 9 9 3 HEAT repeat Importin_rep_4 PF18808.1 OQS07098.1 - 2.5e-13 50.1 0.9 2.2e-12 47.1 0.0 3.2 3 0 0 3 3 3 1 Importin repeat HEAT_EZ PF13513.6 OQS07098.1 - 2.7e-12 46.9 25.5 2e-06 28.1 0.0 10.4 12 1 0 12 12 12 3 HEAT-like repeat HEAT_2 PF13646.6 OQS07098.1 - 8.9e-08 32.4 14.6 0.00017 21.9 0.0 7.8 6 3 4 10 10 9 1 HEAT repeats MMS19_C PF12460.8 OQS07098.1 - 0.00012 21.4 1.0 0.0087 15.2 0.0 4.0 5 0 0 5 5 5 1 RNAPII transcription regulator C-terminal Adaptin_N PF01602.20 OQS07098.1 - 0.00032 19.4 1.5 0.21 10.1 0.0 4.0 5 1 0 5 5 5 2 Adaptin N terminal region IFRD PF05004.13 OQS07098.1 - 0.0014 17.8 9.7 0.61 9.1 0.1 5.6 4 2 2 6 6 6 1 Interferon-related developmental regulator (IFRD) CAS_CSE1 PF03378.15 OQS07098.1 - 0.0062 15.1 3.3 0.48 8.9 0.0 4.4 5 0 0 5 5 5 1 CAS/CSE protein, C-terminus RIX1 PF08167.12 OQS07098.1 - 0.022 14.5 2.1 0.16 11.7 1.1 3.2 2 1 0 2 2 2 0 rRNA processing/ribosome biogenesis Cnd1 PF12717.7 OQS07098.1 - 0.027 14.5 0.0 6 6.9 0.0 4.1 4 0 0 4 4 4 0 non-SMC mitotic condensation complex subunit 1 Sec7_N PF12783.7 OQS07098.1 - 0.043 13.7 2.5 23 4.9 0.7 4.5 4 1 1 5 5 5 0 Guanine nucleotide exchange factor in Golgi transport N-terminal Vac14_Fab1_bd PF12755.7 OQS07098.1 - 0.055 14.1 3.6 0.84 10.3 0.0 4.4 6 0 0 6 6 5 0 Vacuolar 14 Fab1-binding region Tti2 PF10521.9 OQS07098.1 - 0.056 13.0 0.1 6.7 6.2 0.0 3.7 4 1 0 4 4 4 0 Tti2 family FA_hydroxylase PF04116.13 OQS07099.1 - 2.8e-20 73.0 10.3 2.8e-20 73.0 10.3 1.9 3 0 0 3 3 3 1 Fatty acid hydroxylase superfamily COX7B PF05392.11 OQS07099.1 - 0.00058 19.5 0.0 0.0012 18.4 0.0 1.5 1 0 0 1 1 1 1 Cytochrome C oxidase chain VIIB HPS6 PF15702.5 OQS07099.1 - 0.15 10.0 0.0 0.21 9.6 0.0 1.1 1 0 0 1 1 1 0 Hermansky-Pudlak syndrome 6 protein Ribosomal_S8e PF01201.22 OQS07100.1 - 4.5e-50 169.4 3.2 1.3e-49 167.9 3.2 1.7 1 1 0 1 1 1 1 Ribosomal protein S8e BRCT PF00533.26 OQS07101.1 - 0.00038 20.8 0.0 0.12 12.8 0.0 2.8 2 0 0 2 2 2 2 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 OQS07101.1 - 0.0014 19.0 0.0 0.0031 17.9 0.0 1.6 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain RTT107_BRCT_5 PF16770.5 OQS07101.1 - 0.0025 17.7 0.0 0.0086 15.9 0.0 1.9 1 0 0 1 1 1 1 Regulator of Ty1 transposition protein 107 BRCT domain UPF0262 PF06793.12 OQS07101.1 - 0.024 14.7 0.0 0.048 13.8 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0262) RTT107_BRCT_5 PF16770.5 OQS07102.1 - 2.7e-05 24.0 2.4 3.4e-05 23.7 0.0 2.4 2 0 0 2 2 2 1 Regulator of Ty1 transposition protein 107 BRCT domain BRCT_2 PF16589.5 OQS07102.1 - 0.00014 22.2 0.0 0.0012 19.2 0.0 2.4 2 0 0 2 2 2 1 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 OQS07102.1 - 0.00036 20.8 0.1 0.0054 17.1 0.1 2.6 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain NHL PF01436.21 OQS07103.1 - 1.4e-24 84.8 10.3 2.5e-09 36.7 0.2 6.2 5 0 0 5 5 5 4 NHL repeat EGF_2 PF07974.13 OQS07103.1 - 6.7e-19 68.0 185.7 0.0026 18.1 6.8 14.4 10 1 3 13 13 12 11 EGF-like domain PDZ PF00595.24 OQS07103.1 - 3.8e-15 56.0 0.2 0.015 15.7 0.0 6.2 6 0 0 6 6 6 3 PDZ domain LCCL PF03815.19 OQS07103.1 - 9e-15 54.6 0.3 9e-15 54.6 0.3 2.5 2 0 0 2 2 1 1 LCCL domain Kelch_3 PF13415.6 OQS07103.1 - 1.7e-14 53.7 1.0 0.65 10.3 0.0 7.6 7 0 0 7 7 7 5 Galactose oxidase, central domain Kelch_5 PF13854.6 OQS07103.1 - 3.4e-14 52.5 13.8 0.0032 17.4 0.0 7.7 8 0 0 8 8 8 4 Kelch motif Kelch_2 PF07646.15 OQS07103.1 - 3.3e-10 39.5 7.8 0.0019 18.1 0.1 6.2 6 0 0 6 6 5 2 Kelch motif PDZ_6 PF17820.1 OQS07103.1 - 2.4e-08 33.7 0.6 0.012 15.4 0.1 5.3 7 0 0 7 7 6 2 PDZ domain Kelch_6 PF13964.6 OQS07103.1 - 4.2e-08 33.2 0.5 0.54 10.6 0.0 5.2 4 0 0 4 4 4 2 Kelch motif Kelch_1 PF01344.25 OQS07103.1 - 1.2e-07 31.2 4.9 0.00029 20.3 0.1 4.7 4 0 0 4 4 4 1 Kelch motif SGL PF08450.12 OQS07103.1 - 6.1e-05 22.7 0.3 0.54 9.8 0.0 3.8 4 0 0 4 4 4 2 SMP-30/Gluconolactonase/LRE-like region SBBP PF06739.11 OQS07103.1 - 0.00055 19.9 0.7 0.0025 17.8 0.7 2.2 1 0 0 1 1 1 1 Beta-propeller repeat hEGF PF12661.7 OQS07103.1 - 0.0013 19.3 150.3 0.043 14.5 6.0 13.8 12 0 0 12 12 11 8 Human growth factor-like EGF EGF PF00008.27 OQS07103.1 - 0.0057 16.9 2.8 0.0057 16.9 2.8 13.5 14 0 0 14 14 10 5 EGF-like domain Rxt3 PF08642.10 OQS07103.1 - 0.047 14.5 0.4 0.5 11.1 0.0 2.4 2 0 0 2 2 2 0 Histone deacetylation protein Rxt3 TPR_2 PF07719.17 OQS07103.1 - 0.091 12.9 12.3 2.2 8.6 0.4 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.28 OQS07103.1 - 0.16 11.8 7.7 3.4 7.6 1.9 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.6 OQS07103.1 - 0.21 11.9 5.7 1.3 9.3 1.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat MIT PF04212.18 OQS07103.1 - 0.32 11.1 1.2 0.81 9.8 0.6 2.0 2 0 0 2 2 1 0 MIT (microtubule interacting and transport) domain TPR_11 PF13414.6 OQS07103.1 - 5.2 6.8 5.5 3.2 7.5 3.3 1.9 2 0 0 2 2 2 0 TPR repeat Synaptobrevin PF00957.21 OQS07104.1 - 2.5e-25 88.1 4.1 4.1e-25 87.4 4.1 1.4 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.6 OQS07104.1 - 8.2e-16 57.8 0.2 1.4e-15 57.1 0.2 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain DUF844 PF05815.11 OQS07104.1 - 0.0046 16.2 0.3 0.0056 15.9 0.3 1.2 1 0 0 1 1 1 1 Baculovirus protein of unknown function (DUF844) MCU PF04678.13 OQS07104.1 - 0.01 15.9 1.7 0.016 15.3 1.7 1.2 1 0 0 1 1 1 0 Mitochondrial calcium uniporter Tubulin_C PF03953.17 OQS07104.1 - 0.015 15.5 0.7 0.43 10.7 0.3 2.2 2 0 0 2 2 2 0 Tubulin C-terminal domain WW PF00397.26 OQS07105.1 - 5.3e-39 132.0 26.1 8.3e-07 29.0 0.6 6.4 6 0 0 6 6 6 6 WW domain IQ PF00612.27 OQS07105.1 - 6.9e-12 44.1 48.5 0.0026 17.4 2.4 9.4 9 0 0 9 9 9 6 IQ calmodulin-binding motif PKcGMP_CC PF16808.5 OQS07105.1 - 0.0053 16.6 5.7 0.016 15.1 5.7 1.7 1 0 0 1 1 1 1 Coiled-coil N-terminus of cGMP-dependent protein kinase Glyco_hyd_101C PF17451.2 OQS07105.1 - 0.0086 16.4 17.5 5.2 7.4 0.0 5.8 6 1 0 6 6 6 3 Glycosyl hydrolase 101 beta sandwich domain Tup_N PF08581.10 OQS07105.1 - 0.019 15.2 5.9 0.048 14.0 5.8 1.7 1 1 0 1 1 1 0 Tup N-terminal Fib_alpha PF08702.10 OQS07105.1 - 0.02 15.1 5.4 0.072 13.3 5.4 2.0 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family DZR PF12773.7 OQS07105.1 - 0.029 14.4 7.1 0.1 12.6 7.1 1.9 1 0 0 1 1 1 0 Double zinc ribbon FapA PF03961.13 OQS07105.1 - 0.037 12.6 2.7 0.068 11.8 2.7 1.3 1 0 0 1 1 1 0 Flagellar Assembly Protein A AAA_23 PF13476.6 OQS07105.1 - 0.099 13.1 3.4 0.23 11.9 3.4 1.6 1 0 0 1 1 1 0 AAA domain DUF3552 PF12072.8 OQS07105.1 - 0.11 11.9 9.6 0.22 10.9 9.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) DUF641 PF04859.12 OQS07105.1 - 0.37 11.1 7.9 0.25 11.7 5.2 2.1 1 1 0 1 1 1 0 Plant protein of unknown function (DUF641) DUF4407 PF14362.6 OQS07105.1 - 0.41 9.9 7.0 0.66 9.3 7.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Exonuc_VII_L PF02601.15 OQS07105.1 - 0.75 9.3 6.7 2 7.9 6.7 1.6 1 0 0 1 1 1 0 Exonuclease VII, large subunit LRS4 PF10422.9 OQS07105.1 - 0.94 9.0 11.5 0.2 11.2 7.3 1.9 2 0 0 2 2 2 0 Monopolin complex subunit LRS4 YlqD PF11068.8 OQS07105.1 - 1 9.7 9.7 2.7 8.4 9.7 1.7 1 0 0 1 1 1 0 YlqD protein Fer4_2 PF12797.7 OQS07105.1 - 3.7 7.9 5.8 2.6 8.3 2.3 2.6 2 0 0 2 2 2 0 4Fe-4S binding domain zinc_ribbon_2 PF13240.6 OQS07105.1 - 4.3 7.2 6.9 9 6.2 6.9 1.6 1 0 0 1 1 1 0 zinc-ribbon domain OmpH PF03938.14 OQS07105.1 - 4.5 7.6 10.6 14 6.0 10.6 1.9 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Spc24 PF08286.11 OQS07105.1 - 4.6 7.5 7.9 23 5.3 7.9 2.2 1 1 0 1 1 1 0 Spc24 subunit of Ndc80 HSP70 PF00012.20 OQS07105.1 - 9.5 4.3 6.3 15 3.6 6.3 1.2 1 0 0 1 1 1 0 Hsp70 protein Fer4_6 PF12837.7 OQS07105.1 - 9.6 6.5 9.2 0.45 10.7 1.1 2.9 3 0 0 3 3 3 0 4Fe-4S binding domain SPOC PF07744.13 OQS07106.1 - 0.00052 20.0 0.0 0.0011 19.0 0.0 1.5 1 0 0 1 1 1 1 SPOC domain RepB PF07506.11 OQS07106.1 - 0.17 12.0 0.5 0.32 11.1 0.5 1.4 1 0 0 1 1 1 0 RepB plasmid partitioning protein Thiolase_N PF00108.23 OQS07107.1 - 6.1e-71 238.8 1.8 3e-70 236.5 0.2 2.5 3 0 0 3 3 3 1 Thiolase, N-terminal domain Peptidase_M24 PF00557.24 OQS07107.1 - 2.6e-46 158.0 0.0 5.4e-46 156.9 0.0 1.6 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.16 OQS07107.1 - 1.5e-36 124.8 0.0 3.6e-36 123.6 0.0 1.6 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain Thiolase_C PF02803.18 OQS07107.1 - 1.1e-34 118.8 0.2 2.4e-34 117.6 0.0 1.7 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 OQS07107.1 - 1.4e-05 24.8 1.5 2.6e-05 23.9 0.2 2.1 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain SpoVAD PF07451.11 OQS07107.1 - 0.0001 21.1 0.3 0.00029 19.7 0.1 1.8 2 0 0 2 2 2 1 Stage V sporulation protein AD (SpoVAD) Proteasome PF00227.26 OQS07108.1 - 6.8e-59 198.5 0.2 8.2e-59 198.3 0.2 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 OQS07108.1 - 6.1e-14 51.4 0.1 1.2e-13 50.5 0.1 1.5 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature DUF3842 PF12953.7 OQS07108.1 - 0.27 11.6 0.1 0.27 11.6 0.1 1.9 2 1 0 2 2 2 0 Domain of unknown function (DUF3842) Peptidase_M16 PF00675.20 OQS07109.1 - 4.1e-54 182.6 0.1 6.9e-54 181.9 0.1 1.4 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 OQS07109.1 - 1.1e-37 129.8 0.0 3.6e-36 124.9 0.0 2.1 2 0 0 2 2 2 1 Peptidase M16 inactive domain M16C_assoc PF08367.11 OQS07109.1 - 0.065 12.4 0.4 0.13 11.4 0.4 1.5 1 1 0 1 1 1 0 Peptidase M16C associated RbsD_FucU PF05025.13 OQS07109.1 - 0.08 13.4 0.2 0.83 10.1 0.1 2.4 2 0 0 2 2 2 0 RbsD / FucU transport protein family DUF1840 PF08895.11 OQS07109.1 - 0.18 12.1 1.1 24 5.3 0.3 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1840) p450 PF00067.22 OQS07110.1 - 1.3e-24 86.8 0.0 4.5e-24 85.0 0.0 1.8 1 1 0 1 1 1 1 Cytochrome P450 Lipoxygenase PF00305.19 OQS07110.1 - 2.7e-11 42.7 4.0 3.6e-11 42.2 1.4 2.2 2 1 0 2 2 2 1 Lipoxygenase Alginate_lyase PF05426.12 OQS07111.1 - 8.1e-06 25.6 0.0 0.00012 21.8 0.0 2.3 2 0 0 2 2 2 1 Alginate lyase Get5_C PF18514.1 OQS07111.1 - 0.095 12.4 0.5 4 7.3 0.0 2.8 2 0 0 2 2 2 0 Get5 C-terminal domain Pkinase_Tyr PF07714.17 OQS07112.1 - 1e-10 41.3 0.0 1.3e-09 37.8 0.0 2.3 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.25 OQS07112.1 - 4.3e-09 36.1 0.0 1.5e-06 27.8 0.0 3.3 4 0 0 4 4 4 1 Protein kinase domain SKG6 PF08693.10 OQS07112.1 - 0.0026 17.1 0.5 0.0026 17.1 0.5 1.8 2 0 0 2 2 2 1 Transmembrane alpha-helix domain EphA2_TM PF14575.6 OQS07112.1 - 0.0083 17.0 0.2 2.4 9.1 0.0 2.4 2 0 0 2 2 2 1 Ephrin type-A receptor 2 transmembrane domain Syndecan PF01034.20 OQS07112.1 - 0.098 12.6 2.5 3.3 7.7 0.1 2.4 2 0 0 2 2 2 0 Syndecan domain DUF347 PF03988.12 OQS07112.1 - 0.14 12.3 2.9 0.97 9.7 0.1 2.4 2 0 0 2 2 2 0 Repeat of Unknown Function (DUF347) Orthoreo_P10 PF07204.11 OQS07112.1 - 0.32 11.0 3.9 11 6.1 0.1 3.0 3 0 0 3 3 3 0 Orthoreovirus membrane fusion protein p10 DIM PF08194.12 OQS07113.1 - 0.47 10.7 3.2 46 4.3 0.1 4.0 4 0 0 4 4 4 0 DIM protein Ank_2 PF12796.7 OQS07114.1 - 8.8e-21 74.3 0.8 2.3e-14 53.7 0.1 2.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQS07114.1 - 2.3e-20 72.7 0.1 4.3e-09 36.7 0.0 3.4 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 OQS07114.1 - 2.6e-16 59.5 0.2 2.1e-08 34.3 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 OQS07114.1 - 5.4e-16 58.2 0.9 1.8e-05 24.9 0.1 3.8 4 0 0 4 4 4 2 Ankyrin repeat Ank_3 PF13606.6 OQS07114.1 - 4.5e-11 42.0 0.0 0.00019 21.6 0.0 4.7 5 1 0 5 5 5 2 Ankyrin repeat Pkinase PF00069.25 OQS07115.1 - 4.3e-48 164.0 0.0 4.1e-47 160.8 0.0 1.9 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQS07115.1 - 3.3e-47 161.0 0.0 5.1e-47 160.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OQS07115.1 - 7.7e-05 21.6 0.0 0.00012 21.0 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase DUF3377 PF11857.8 OQS07115.1 - 0.01 15.8 0.0 0.023 14.6 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) Flu_NS2 PF00601.19 OQS07115.1 - 0.021 15.1 0.0 0.058 13.7 0.0 1.7 1 0 0 1 1 1 0 Influenza non-structural protein (NS2) APH PF01636.23 OQS07115.1 - 0.1 12.5 0.0 0.15 11.9 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 OQS07115.1 - 0.11 11.4 0.0 0.24 10.3 0.0 1.5 1 0 0 1 1 1 0 Haspin like kinase domain Ssl1 PF04056.14 OQS07116.1 - 3.2e-69 232.6 0.0 4.2e-69 232.2 0.0 1.1 1 0 0 1 1 1 1 Ssl1-like VWA_2 PF13519.6 OQS07116.1 - 2.5e-14 53.8 0.0 4.7e-14 52.9 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain C1_4 PF07975.12 OQS07116.1 - 1.8e-08 34.5 17.3 1.8e-08 34.5 17.3 2.9 2 1 0 2 2 2 1 TFIIH C1-like domain Tfb4 PF03850.14 OQS07116.1 - 5.9e-05 22.7 3.0 5.9e-05 22.7 3.0 2.3 2 1 0 2 2 2 1 Transcription factor Tfb4 VWA PF00092.28 OQS07116.1 - 0.00029 21.1 0.0 0.00047 20.4 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.6 OQS07116.1 - 0.0057 16.6 0.0 0.012 15.5 0.0 1.5 2 0 0 2 2 2 1 von Willebrand factor type A domain PAC2 PF09754.9 OQS07116.1 - 0.026 14.5 0.0 0.036 14.1 0.0 1.2 1 0 0 1 1 1 0 PAC2 family VPS9 PF02204.18 OQS07118.1 - 5.1e-18 65.2 0.8 1.2e-17 64.0 0.1 2.0 2 0 0 2 2 2 1 Vacuolar sorting protein 9 (VPS9) domain PH PF00169.29 OQS07118.1 - 2.2e-16 60.3 0.1 4.5e-16 59.3 0.1 1.6 1 0 0 1 1 1 1 PH domain PH_8 PF15409.6 OQS07118.1 - 4.2e-08 33.4 0.2 1.1e-07 32.1 0.2 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain PH_11 PF15413.6 OQS07118.1 - 7.8e-07 29.5 0.9 2.7e-06 27.7 0.9 2.0 1 1 0 1 1 1 1 Pleckstrin homology domain Pex24p PF06398.11 OQS07118.1 - 3.7e-06 26.2 1.0 3.7e-06 26.2 1.0 2.1 3 0 0 3 3 3 1 Integral peroxisomal membrane peroxin PH_9 PF15410.6 OQS07118.1 - 0.035 14.5 0.1 0.16 12.3 0.1 2.1 1 0 0 1 1 1 0 Pleckstrin homology domain ComJ PF11033.8 OQS07118.1 - 0.04 13.6 0.0 9.7 5.9 0.0 2.4 2 0 0 2 2 2 0 Competence protein J (ComJ) HisG_C PF08029.11 OQS07118.1 - 0.06 13.5 0.0 0.15 12.2 0.0 1.6 1 0 0 1 1 1 0 HisG, C-terminal domain Lipoxygenase PF00305.19 OQS07119.1 - 2.6e-12 46.0 0.7 8.8e-12 44.3 0.7 1.8 1 1 0 1 1 1 1 Lipoxygenase p450 PF00067.22 OQS07119.1 - 2.9e-09 36.2 0.2 1.9e-08 33.5 0.2 2.0 1 1 0 1 1 1 1 Cytochrome P450 DUF4176 PF13780.6 OQS07119.1 - 0.11 12.6 0.0 0.26 11.3 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4176) Pkinase PF00069.25 OQS07120.1 - 1.2e-45 155.9 0.0 1.8e-45 155.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQS07120.1 - 1.5e-43 149.0 0.0 2.2e-43 148.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OQS07120.1 - 0.0019 17.1 0.0 0.0024 16.7 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase DUF4064 PF13273.6 OQS07120.1 - 0.015 15.6 0.3 0.034 14.4 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4064) APH PF01636.23 OQS07120.1 - 0.092 12.7 0.0 0.15 12.0 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family adh_short_C2 PF13561.6 OQS07122.1 - 1.7e-51 175.1 0.2 2.4e-51 174.5 0.2 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OQS07122.1 - 8.4e-35 120.0 0.0 1.5e-34 119.2 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase SAS-6_N PF16531.5 OQS07122.1 - 2.8e-25 88.7 2.9 5.6e-25 87.7 2.9 1.5 1 0 0 1 1 1 1 Centriolar protein SAS N-terminal KR PF08659.10 OQS07122.1 - 0.00011 22.1 0.0 0.00027 20.9 0.0 1.6 1 0 0 1 1 1 1 KR domain FMN_bind_2 PF04299.12 OQS07123.1 - 1.4e-53 181.1 1.7 1.7e-53 180.8 1.7 1.1 1 0 0 1 1 1 1 Putative FMN-binding domain Nt_Gln_amidase PF09764.9 OQS07123.1 - 0.066 12.8 0.2 0.093 12.3 0.2 1.2 1 0 0 1 1 1 0 N-terminal glutamine amidase Glyco_transf_28 PF03033.20 OQS07124.1 - 2.4e-17 63.3 0.0 8.5e-17 61.5 0.0 1.9 1 1 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain Glyco_transf_28 PF03033.20 OQS07126.1 - 2.6e-30 105.3 0.0 4.1e-19 69.0 0.0 3.2 2 1 0 2 2 2 2 Glycosyltransferase family 28 N-terminal domain ATG_C PF09333.11 OQS07126.1 - 0.00039 20.7 0.1 0.0021 18.4 0.0 2.3 2 0 0 2 2 2 1 Autophagy-related protein C terminal domain UDPGT PF00201.18 OQS07126.1 - 0.001 17.9 0.1 0.0019 17.1 0.1 1.3 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase VPS13_C PF16909.5 OQS07126.1 - 0.038 13.8 0.1 0.079 12.7 0.1 1.5 1 0 0 1 1 1 0 Vacuolar-sorting-associated 13 protein C-terminal Pkinase PF00069.25 OQS07127.1 - 2.4e-50 171.4 0.0 3.1e-50 171.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQS07127.1 - 1.3e-37 129.6 0.0 1.5e-37 129.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OQS07127.1 - 3.8e-06 25.9 0.0 4.7e-06 25.6 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 OQS07127.1 - 8e-05 21.7 0.0 0.00018 20.6 0.0 1.6 2 0 0 2 2 2 1 Haspin like kinase domain Kinase-like PF14531.6 OQS07127.1 - 0.00015 21.2 0.0 0.0066 15.8 0.0 2.3 2 1 0 2 2 2 1 Kinase-like Kdo PF06293.14 OQS07127.1 - 0.00025 20.4 0.0 0.00042 19.7 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OQS07127.1 - 0.028 14.3 0.4 1.1 9.1 0.1 2.4 1 1 1 2 2 2 0 Phosphotransferase enzyme family Pkinase PF00069.25 OQS07128.1 - 3.3e-49 167.6 0.0 2.2e-48 165.0 0.0 1.9 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQS07128.1 - 5.5e-49 166.8 0.0 6.6e-48 163.3 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase Gal_Lectin PF02140.18 OQS07128.1 - 1.3e-15 57.6 2.3 1.3e-15 57.6 2.3 2.3 2 0 0 2 2 1 1 Galactose binding lectin domain TMEM154 PF15102.6 OQS07128.1 - 3.2e-06 27.1 0.1 7e-06 26.0 0.1 1.5 1 0 0 1 1 1 1 TMEM154 protein family SKG6 PF08693.10 OQS07128.1 - 0.00036 19.9 3.4 0.00066 19.0 3.4 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain RIFIN PF02009.16 OQS07128.1 - 0.0009 19.2 1.1 0.0022 17.9 1.1 1.8 1 1 0 1 1 1 1 Rifin CD34_antigen PF06365.12 OQS07128.1 - 0.0016 18.1 0.1 0.018 14.6 0.0 2.1 2 0 0 2 2 2 1 CD34/Podocalyxin family ECSCR PF15820.5 OQS07128.1 - 0.003 17.4 0.1 0.0065 16.3 0.1 1.5 1 0 0 1 1 1 1 Endothelial cell-specific chemotaxis regulator EphA2_TM PF14575.6 OQS07128.1 - 0.0056 17.5 0.0 0.011 16.6 0.0 1.4 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain DAG1 PF05454.11 OQS07128.1 - 0.0072 15.7 0.1 0.021 14.2 0.1 1.7 2 0 0 2 2 2 1 Dystroglycan (Dystrophin-associated glycoprotein 1) Pkinase_fungal PF17667.1 OQS07128.1 - 0.011 14.6 0.0 0.017 13.9 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase DUF3827 PF12877.7 OQS07128.1 - 0.011 14.1 1.2 0.016 13.6 1.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) Insulin_TMD PF17870.1 OQS07128.1 - 0.014 15.5 2.3 0.027 14.6 2.3 1.4 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment DUF4448 PF14610.6 OQS07128.1 - 0.024 14.4 0.0 0.05 13.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) Adeno_E3_CR2 PF02439.15 OQS07128.1 - 0.024 14.4 4.6 0.046 13.5 4.6 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Mid2 PF04478.12 OQS07128.1 - 0.027 14.3 0.4 0.076 12.9 0.4 1.7 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor Orf78 PF06024.12 OQS07128.1 - 0.035 14.4 0.0 0.079 13.3 0.0 1.5 1 0 0 1 1 1 0 Orf78 (ac78) Stevor PF17410.2 OQS07128.1 - 0.039 13.5 0.2 0.077 12.5 0.2 1.5 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame ASFV_J13L PF05568.11 OQS07128.1 - 0.065 13.0 0.0 0.16 11.7 0.0 1.7 1 0 0 1 1 1 0 African swine fever virus J13L protein TMEM51 PF15345.6 OQS07128.1 - 0.11 12.3 0.0 0.18 11.6 0.0 1.2 1 0 0 1 1 1 0 Transmembrane protein 51 SP_C-Propep PF08999.10 OQS07128.1 - 0.12 12.2 1.8 0.27 11.0 1.8 1.5 1 0 0 1 1 1 0 Surfactant protein C, N terminal propeptide Kdo PF06293.14 OQS07128.1 - 0.15 11.4 0.0 0.23 10.8 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family CPG4 PF15481.6 OQS07128.1 - 0.19 12.4 6.5 0.094 13.3 2.5 2.4 2 0 0 2 2 2 0 Chondroitin proteoglycan 4 DUF4834 PF16118.5 OQS07128.1 - 0.2 12.7 0.0 0.37 11.8 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) DUF2574 PF10836.8 OQS07128.1 - 1.1 9.1 4.6 2.5 8.0 0.1 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2574) RCC1 PF00415.18 OQS07129.1 - 3.4e-70 232.5 20.7 5.6e-12 46.1 0.1 7.4 7 0 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 OQS07129.1 - 1.3e-29 101.4 35.1 3.5e-08 33.0 2.5 7.5 8 0 0 8 8 8 5 Regulator of chromosome condensation (RCC1) repeat Kelch_2 PF07646.15 OQS07129.1 - 0.12 12.4 2.8 70 3.6 0.1 3.7 3 0 0 3 3 3 0 Kelch motif Pkinase PF00069.25 OQS07130.1 - 4.7e-44 150.7 0.0 6.8e-44 150.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain COQ9 PF08511.11 OQS07130.1 - 7.8e-35 118.5 0.4 1.4e-34 117.6 0.4 1.5 1 0 0 1 1 1 1 COQ9 Pkinase_Tyr PF07714.17 OQS07130.1 - 1.7e-26 93.1 0.0 2.6e-26 92.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OQS07130.1 - 2.6e-07 30.2 0.0 5.1e-07 29.3 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 OQS07130.1 - 1.1e-05 24.4 0.0 2e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Seadorna_VP7 PF07387.11 OQS07130.1 - 0.037 13.1 0.1 0.061 12.4 0.1 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Kdo PF06293.14 OQS07130.1 - 0.059 12.7 0.1 0.12 11.7 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Trypsin_2 PF13365.6 OQS07131.1 - 2.4e-12 48.0 0.0 5.6e-12 46.8 0.0 1.7 1 1 0 1 1 1 1 Trypsin-like peptidase domain YdaS_antitoxin PF15943.5 OQS07131.1 - 0.0059 16.5 0.0 30 4.6 0.0 4.6 4 0 0 4 4 4 1 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT Peptidase_C4 PF00863.19 OQS07131.1 - 0.099 11.9 0.0 0.2 10.9 0.0 1.4 1 0 0 1 1 1 0 Peptidase family C4 DUF4597 PF15366.6 OQS07131.1 - 0.17 11.7 0.0 0.55 10.0 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4597) Peptidase_S46 PF10459.9 OQS07131.1 - 0.2 10.2 0.1 0.41 9.2 0.1 1.4 1 0 0 1 1 1 0 Peptidase S46 Pkinase PF00069.25 OQS07132.1 - 1.2e-49 169.1 0.0 1.9e-49 168.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQS07132.1 - 4.7e-48 163.7 0.0 6.7e-48 163.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Gal_Lectin PF02140.18 OQS07132.1 - 1.9e-16 60.2 1.1 7.7e-16 58.3 1.1 2.1 1 0 0 1 1 1 1 Galactose binding lectin domain ASFV_J13L PF05568.11 OQS07132.1 - 2.3e-05 24.3 0.4 5.7e-05 23.0 0.4 1.6 1 0 0 1 1 1 1 African swine fever virus J13L protein TMEM154 PF15102.6 OQS07132.1 - 4.4e-05 23.4 1.4 9e-05 22.4 1.4 1.5 1 0 0 1 1 1 1 TMEM154 protein family Glycophorin_A PF01102.18 OQS07132.1 - 0.003 17.8 0.7 0.0062 16.8 0.7 1.5 1 0 0 1 1 1 1 Glycophorin A RIFIN PF02009.16 OQS07132.1 - 0.0045 16.9 0.4 0.0084 16.0 0.4 1.4 1 0 0 1 1 1 1 Rifin Pkinase_fungal PF17667.1 OQS07132.1 - 0.0093 14.8 0.1 0.015 14.1 0.1 1.2 1 0 0 1 1 1 1 Fungal protein kinase PRIMA1 PF16101.5 OQS07132.1 - 0.011 15.8 3.0 0.026 14.5 3.0 1.6 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 Endomucin PF07010.12 OQS07132.1 - 0.026 14.5 12.4 0.057 13.4 12.4 1.5 1 0 0 1 1 1 0 Endomucin Pex2_Pex12 PF04757.14 OQS07132.1 - 0.039 13.6 0.0 0.087 12.4 0.0 1.5 1 0 0 1 1 1 0 Pex2 / Pex12 amino terminal region EphA2_TM PF14575.6 OQS07132.1 - 0.052 14.4 0.0 0.12 13.3 0.0 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain ECSCR PF15820.5 OQS07132.1 - 0.054 13.3 0.3 0.12 12.2 0.3 1.5 1 0 0 1 1 1 0 Endothelial cell-specific chemotaxis regulator CD34_antigen PF06365.12 OQS07132.1 - 0.069 12.7 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 CD34/Podocalyxin family Kinase-like PF14531.6 OQS07132.1 - 0.16 11.3 0.0 0.25 10.6 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Haspin_kinase PF12330.8 OQS07132.1 - 0.23 10.3 1.6 0.39 9.6 0.1 2.0 2 0 0 2 2 2 0 Haspin like kinase domain CtsR PF05848.11 OQS07133.1 - 0.00043 20.1 0.0 30 4.6 0.0 4.4 4 0 0 4 4 4 3 CtsR N-terminal HTH domain PX PF00787.24 OQS07135.1 - 0.0039 17.1 0.5 0.0086 16.0 0.5 1.6 1 1 0 1 1 1 1 PX domain Hydrolase_4 PF12146.8 OQS07136.1 - 4.1e-14 52.4 0.0 1.8e-07 30.7 0.0 2.8 2 1 0 2 2 2 2 Serine aminopeptidase, S33 LpxB PF02684.15 OQS07137.1 - 3.4e-40 138.0 5.6 2.1e-26 92.7 3.2 2.0 2 0 0 2 2 2 2 Lipid-A-disaccharide synthetase PIP5K PF01504.18 OQS07138.1 - 7.2e-125 415.7 12.9 7.5e-62 209.0 3.4 4.0 2 2 0 2 2 2 2 Phosphatidylinositol-4-phosphate 5-Kinase YonK PF09642.10 OQS07138.1 - 0.12 12.5 0.8 0.33 11.1 0.2 2.0 2 0 0 2 2 2 0 YonK protein DUF5313 PF17240.2 OQS07138.1 - 1.3 9.4 10.8 1.3 9.5 3.0 3.1 2 0 0 2 2 2 0 Family of unknown function (DUF5313) EXS PF03124.14 OQS07139.1 - 5.9e-80 269.1 21.5 1.1e-79 268.2 21.5 1.4 1 0 0 1 1 1 1 EXS family PBC PF03792.13 OQS07139.1 - 0.05 13.4 0.2 0.092 12.5 0.2 1.3 1 0 0 1 1 1 0 PBC domain BLOC1_2 PF10046.9 OQS07139.1 - 0.16 12.3 0.1 0.52 10.6 0.0 1.8 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Ribosomal_L36e PF01158.18 OQS07139.1 - 0.22 11.8 0.0 0.52 10.6 0.0 1.5 1 0 0 1 1 1 0 Ribosomal protein L36e PX PF00787.24 OQS07140.1 - 0.017 15.1 0.3 0.1 12.6 0.3 2.1 1 1 0 1 1 1 0 PX domain Lipase_3 PF01764.25 OQS07141.1 - 1.9e-10 40.8 0.0 4.4e-10 39.6 0.0 1.6 1 0 0 1 1 1 1 Lipase (class 3) DUF2974 PF11187.8 OQS07141.1 - 0.0033 17.0 0.2 0.059 12.9 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF2974) Abhydrolase_6 PF12697.7 OQS07141.1 - 0.02 15.5 0.0 0.064 13.8 0.0 1.9 1 0 0 1 1 1 0 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 OQS07141.1 - 0.14 11.4 0.0 0.26 10.5 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Abhydrolase_5 PF12695.7 OQS07141.1 - 0.16 11.8 0.0 0.29 10.9 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family Ank_4 PF13637.6 OQS07142.1 - 6.4e-54 179.7 33.6 2.8e-06 27.7 0.0 14.1 11 4 3 14 14 14 9 Ankyrin repeats (many copies) Ank_2 PF12796.7 OQS07142.1 - 5.1e-52 174.4 36.7 2.7e-08 34.3 0.2 10.4 2 2 10 12 12 12 11 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OQS07142.1 - 8.7e-41 137.5 35.4 0.0021 18.3 0.1 18.5 6 4 13 20 20 20 13 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQS07142.1 - 5.6e-28 93.9 24.1 1.5 9.6 0.0 19.7 19 3 3 22 22 22 5 Ankyrin repeat DUF5049 PF16468.5 OQS07142.1 - 2e-08 34.0 15.7 6.5 6.7 0.0 12.4 10 4 5 15 15 15 1 Domain of unknown function (DUF5049) Ank PF00023.30 OQS07142.1 - 3.3e-08 33.6 18.2 14 6.3 1.6 14.5 7 5 1 8 8 8 1 Ankyrin repeat DUF1843 PF08898.10 OQS07142.1 - 0.0016 18.9 4.4 42 4.7 0.0 7.7 9 1 1 10 10 10 0 Domain of unknown function (DUF1843) AhpC-TSA PF00578.21 OQS07142.1 - 0.0035 17.3 0.3 9.5 6.2 0.0 4.6 5 1 0 5 5 5 1 AhpC/TSA family HA PF03457.14 OQS07142.1 - 0.0049 17.2 0.2 34 4.9 0.0 5.1 4 1 0 4 4 4 0 Helicase associated domain DUF5099 PF17025.5 OQS07142.1 - 0.072 13.5 0.1 6.6 7.2 0.0 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF5099) Hydrolase_4 PF12146.8 OQS07143.1 - 7.2e-63 212.0 0.0 8.3e-63 211.8 0.0 1.0 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 OQS07143.1 - 1e-12 48.2 0.2 9.2e-08 32.0 0.2 2.1 1 1 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 OQS07143.1 - 1.8e-08 35.3 0.0 2.1e-08 35.0 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 OQS07143.1 - 0.0002 20.9 0.0 0.31 10.5 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Tannase PF07519.11 OQS07143.1 - 0.021 13.8 0.0 0.035 13.0 0.0 1.4 1 1 0 1 1 1 0 Tannase and feruloyl esterase UPF0227 PF05728.12 OQS07143.1 - 0.026 14.5 0.1 1 9.3 0.0 2.1 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0227) Abhydrolase_5 PF12695.7 OQS07143.1 - 0.056 13.2 0.0 0.13 12.0 0.0 1.6 2 0 0 2 2 2 0 Alpha/beta hydrolase family Chlorophyllase2 PF12740.7 OQS07143.1 - 0.079 11.9 0.0 0.11 11.4 0.0 1.1 1 0 0 1 1 1 0 Chlorophyllase enzyme FSH1 PF03959.13 OQS07143.1 - 0.13 11.9 0.2 2.8 7.5 0.0 2.6 3 0 0 3 3 3 0 Serine hydrolase (FSH1) Ead_Ea22 PF13935.6 OQS07144.1 - 0.018 15.7 1.3 0.032 14.9 1.3 1.4 1 0 0 1 1 1 0 Ead/Ea22-like protein VSG_B PF13206.6 OQS07144.1 - 0.4 9.9 1.8 0.58 9.3 1.8 1.2 1 0 0 1 1 1 0 Trypanosomal VSG domain TIR_2 PF13676.6 OQS07145.1 - 6.9e-13 49.2 0.2 8.6e-12 45.7 0.0 2.7 3 0 0 3 3 3 1 TIR domain Ank_2 PF12796.7 OQS07145.1 - 1.8e-08 34.8 1.0 0.00013 22.5 0.1 2.8 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQS07145.1 - 1.3e-05 25.6 1.0 0.32 11.6 0.2 3.2 2 1 0 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 OQS07145.1 - 0.00019 21.6 1.7 0.27 11.6 0.1 3.8 1 1 4 5 5 5 2 Ankyrin repeats (many copies) MEIOC PF15189.6 OQS07145.1 - 0.016 14.8 0.4 0.036 13.7 0.4 1.5 1 0 0 1 1 1 0 Meiosis-specific coiled-coil domain-containing protein MEIOC SAM_1 PF00536.30 OQS07145.1 - 0.046 14.2 0.0 0.15 12.5 0.0 1.9 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) LRR_9 PF14580.6 OQS07146.1 - 9.1e-19 67.6 0.9 9.1e-19 67.6 0.9 1.8 2 0 0 2 2 2 1 Leucine-rich repeat LRR_4 PF12799.7 OQS07146.1 - 2e-10 40.7 5.9 0.0014 19.0 1.1 3.8 2 1 2 4 4 4 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 OQS07146.1 - 0.01 15.6 9.7 0.073 12.9 6.3 2.7 1 1 1 2 2 2 0 Leucine rich repeat LRR_6 PF13516.6 OQS07146.1 - 0.92 9.7 3.7 41 4.6 0.1 3.5 3 0 0 3 3 3 0 Leucine Rich repeat CHAP PF05257.16 OQS07147.1 - 1.1e-08 35.6 0.1 2.1e-08 34.6 0.1 1.5 1 0 0 1 1 1 1 CHAP domain Ank_5 PF13857.6 OQS07148.1 - 3e-05 24.2 0.0 0.61 10.5 0.0 3.5 4 0 0 4 4 4 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 OQS07148.1 - 0.0014 19.2 0.1 0.51 11.0 0.0 2.7 1 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OQS07148.1 - 0.0017 18.7 0.0 1 10.1 0.0 3.9 4 0 0 4 4 4 1 Ankyrin repeat Ank_4 PF13637.6 OQS07148.1 - 0.0049 17.4 0.0 0.97 10.1 0.0 3.0 2 1 0 2 2 2 1 Ankyrin repeats (many copies) LCCL PF03815.19 OQS07149.1 - 7.3e-22 77.3 0.1 1.4e-21 76.3 0.1 1.4 1 0 0 1 1 1 1 LCCL domain Tetraspanin PF00335.20 OQS07149.1 - 0.038 13.7 5.5 0.1 12.3 5.2 1.9 1 1 0 1 1 1 0 Tetraspanin family DUF1422 PF07226.11 OQS07149.1 - 1.4 9.0 12.7 0.14 12.2 1.6 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1422) PI3_PI4_kinase PF00454.27 OQS07150.1 - 2.3e-27 96.4 0.0 3.5e-27 95.8 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase Helicase_C_3 PF13625.6 OQS07150.1 - 0.016 15.4 0.0 0.037 14.2 0.0 1.5 1 0 0 1 1 1 0 Helicase conserved C-terminal domain FYVE PF01363.21 OQS07151.1 - 4.6e-20 71.5 11.4 7.7e-20 70.8 11.4 1.4 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.16 OQS07151.1 - 2.5e-05 24.5 4.9 4.4e-05 23.7 4.9 1.4 1 0 0 1 1 1 1 FYVE-type zinc finger zf-piccolo PF05715.13 OQS07151.1 - 0.088 13.0 9.8 0.084 13.0 5.9 2.3 1 1 1 2 2 2 0 Piccolo Zn-finger PocR PF10114.9 OQS07151.1 - 0.092 12.5 5.2 0.28 11.0 5.2 1.9 1 1 0 1 1 1 0 Sensory domain found in PocR CHAP PF05257.16 OQS07152.1 - 0.16 12.6 0.7 0.43 11.2 0.7 1.7 1 1 0 1 1 1 0 CHAP domain DUF1754 PF08555.10 OQS07153.1 - 3.2e-06 27.8 18.3 3.2e-06 27.8 18.3 2.2 2 1 0 2 2 2 1 Eukaryotic family of unknown function (DUF1754) Dynamin_M PF01031.20 OQS07154.1 - 8.8e-26 90.8 0.0 8.7e-24 84.2 0.0 2.6 2 0 0 2 2 2 2 Dynamin central region Dynamin_N PF00350.23 OQS07154.1 - 1.8e-07 31.4 0.1 3.6e-07 30.4 0.1 1.4 1 0 0 1 1 1 1 Dynamin family GED PF02212.18 OQS07154.1 - 0.0017 18.5 0.2 0.0056 16.8 0.2 1.9 1 0 0 1 1 1 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 OQS07154.1 - 0.0064 16.6 0.1 0.015 15.4 0.1 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase ALGX PF16822.5 OQS07154.1 - 0.1 12.3 0.0 0.17 11.6 0.0 1.3 1 0 0 1 1 1 0 SGNH hydrolase-like domain, acetyltransferase AlgX Gly_transf_sug PF04488.15 OQS07155.1 - 7.9e-31 106.6 0.0 2.3e-14 53.8 0.0 2.4 2 0 0 2 2 2 2 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.12 OQS07155.1 - 8e-16 58.2 3.1 1.6e-07 31.0 0.1 2.2 2 0 0 2 2 2 2 Capsular polysaccharide synthesis protein TcdA_TcdB PF12919.7 OQS07155.1 - 0.0088 15.4 1.4 5.8 6.1 0.0 3.8 4 0 0 4 4 4 1 TcdA/TcdB catalytic glycosyltransferase domain FMN_bind PF04205.14 OQS07155.1 - 0.13 12.9 0.0 0.28 11.8 0.0 1.6 1 0 0 1 1 1 0 FMN-binding domain Ank_4 PF13637.6 OQS07156.1 - 2.7e-17 62.9 4.4 5.9e-06 26.7 0.0 5.2 3 2 1 5 5 5 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 OQS07156.1 - 1.1e-14 54.8 1.8 5.5e-06 26.9 0.2 3.3 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OQS07156.1 - 6.4e-14 51.8 1.1 0.0089 16.3 0.1 5.4 3 2 2 5 5 5 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQS07156.1 - 3.1e-09 36.3 0.6 5.3 7.9 0.0 6.8 5 2 2 7 7 7 2 Ankyrin repeat ENTH PF01417.20 OQS07156.1 - 0.0093 16.0 0.2 0.98 9.5 0.2 2.3 1 1 1 2 2 2 2 ENTH domain Ank PF00023.30 OQS07156.1 - 0.016 15.6 0.1 45 4.7 0.1 4.4 3 1 1 4 4 4 0 Ankyrin repeat FKBP_C PF00254.28 OQS07157.1 - 1.4e-24 86.3 0.0 1.7e-24 85.9 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Glyco_hydro_47 PF01532.20 OQS07158.1 - 6.3e-132 440.7 0.0 7.8e-132 440.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Glyco_hydro_88 PF07470.13 OQS07158.1 - 7.1e-05 22.0 0.7 0.6 9.1 0.0 3.9 3 1 1 4 4 4 3 Glycosyl Hydrolase Family 88 WW PF00397.26 OQS07159.1 - 0.0053 16.8 2.2 16 5.7 0.0 3.6 3 0 0 3 3 3 3 WW domain NRBF2 PF08961.10 OQS07160.1 - 0.00028 20.6 2.3 0.00056 19.6 2.3 1.5 1 0 0 1 1 1 1 Nuclear receptor-binding factor 2, autophagy regulator bZIP_1 PF00170.21 OQS07160.1 - 1.2 9.3 4.8 1.6 8.9 1.7 2.4 1 1 1 2 2 2 0 bZIP transcription factor Rootletin PF15035.6 OQS07160.1 - 1.6 8.7 16.1 1.9 8.5 10.3 2.1 1 1 1 2 2 2 0 Ciliary rootlet component, centrosome cohesion FUSC PF04632.12 OQS07160.1 - 1.7 7.1 4.4 2.5 6.5 4.4 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family Sec2p PF06428.11 OQS07160.1 - 6.3 6.8 10.4 1.3 9.1 6.6 1.8 2 0 0 2 2 2 0 GDP/GTP exchange factor Sec2p Pkinase PF00069.25 OQS07161.1 - 1.4e-77 260.6 0.0 4.2e-77 259.1 0.0 1.9 1 0 0 1 1 1 1 Protein kinase domain Peptidase_C1_2 PF03051.15 OQS07161.1 - 2.1e-53 181.7 4.8 9.8e-41 139.9 0.2 5.2 2 1 2 4 4 4 2 Peptidase C1-like family Pkinase_Tyr PF07714.17 OQS07161.1 - 1.1e-52 178.9 0.0 2e-52 178.0 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase BAR PF03114.18 OQS07161.1 - 4.6e-12 46.1 6.0 1.4e-11 44.5 6.0 1.8 1 0 0 1 1 1 1 BAR domain Kinase-like PF14531.6 OQS07161.1 - 0.00058 19.3 0.1 0.0025 17.2 0.0 1.9 1 1 1 2 2 2 1 Kinase-like Kdo PF06293.14 OQS07161.1 - 0.0045 16.4 0.1 0.013 14.9 0.1 1.7 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Arm PF00514.23 OQS07161.1 - 0.0061 16.6 0.9 2.9 8.1 0.0 4.6 5 0 0 5 5 5 1 Armadillo/beta-catenin-like repeat Histone_H2A_C PF16211.5 OQS07161.1 - 0.061 13.1 0.0 0.24 11.2 0.0 2.0 2 0 0 2 2 2 0 C-terminus of histone H2A V-ATPase_H_C PF11698.8 OQS07161.1 - 0.093 12.9 0.5 0.67 10.1 0.2 2.6 2 0 0 2 2 2 0 V-ATPase subunit H OmpH PF03938.14 OQS07161.1 - 0.12 12.7 6.4 0.36 11.1 6.4 1.8 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Hrs_helical PF12210.8 OQS07161.1 - 1.5 9.4 11.1 0.39 11.3 5.8 2.7 2 0 0 2 2 2 0 Hepatocyte growth factor-regulated tyrosine kinase substrate Epimerase PF01370.21 OQS07162.1 - 1.2e-25 90.4 0.0 1.5e-25 90.1 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 OQS07162.1 - 3.9e-21 75.8 0.0 5.8e-17 62.1 0.0 2.2 2 0 0 2 2 2 2 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 OQS07162.1 - 5.4e-12 45.4 0.0 8e-12 44.9 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain 3Beta_HSD PF01073.19 OQS07162.1 - 2e-09 36.9 0.0 2.8e-09 36.4 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 OQS07162.1 - 1.9e-08 33.8 0.0 9.3e-08 31.5 0.0 2.1 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.12 OQS07162.1 - 3.6e-07 29.6 0.0 4.9e-06 25.9 0.0 2.5 2 1 0 2 2 2 1 Male sterility protein NAD_binding_10 PF13460.6 OQS07162.1 - 0.034 14.0 0.0 0.078 12.9 0.0 1.6 2 0 0 2 2 2 0 NAD(P)H-binding KR PF08659.10 OQS07162.1 - 0.21 11.5 0.1 0.54 10.1 0.1 1.8 2 1 0 2 2 2 0 KR domain Cellulase PF00150.18 OQS07163.1 - 2.3e-28 99.4 1.8 1.2e-27 97.0 2.2 1.8 2 0 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) DUF4044 PF13253.6 OQS07163.1 - 0.14 11.7 4.0 0.27 10.8 4.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4044) FMN_red PF03358.15 OQS07164.1 - 4.1e-17 62.3 0.0 1.2e-16 60.9 0.0 1.7 1 1 1 2 2 2 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 OQS07164.1 - 0.0004 20.2 0.0 0.00055 19.7 0.0 1.2 1 0 0 1 1 1 1 Flavodoxin-like fold PHD PF00628.29 OQS07165.1 - 4.8e-06 26.4 39.8 5.9e-05 22.9 3.6 3.9 4 0 0 4 4 4 3 PHD-finger PX PF00787.24 OQS07166.1 - 6.7e-08 32.5 0.0 1.6e-07 31.3 0.0 1.6 1 0 0 1 1 1 1 PX domain BCAS2 PF05700.11 OQS07167.1 - 9.2e-41 139.8 3.8 1e-40 139.6 3.8 1.0 1 0 0 1 1 1 1 Breast carcinoma amplified sequence 2 (BCAS2) APC1_C PF18122.1 OQS07167.1 - 0.00037 20.5 0.9 0.00063 19.7 0.8 1.4 1 1 0 1 1 1 1 Anaphase-promoting complex sub unit 1 C-terminal domain YCII PF03795.14 OQS07168.1 - 3.9e-08 33.6 0.0 6.1e-08 33.0 0.0 1.3 1 0 0 1 1 1 1 YCII-related domain NolB PF17398.2 OQS07169.1 - 0.1 13.0 0.0 0.25 11.7 0.0 1.6 1 0 0 1 1 1 0 Nodulation protein NolB Tetraspanin PF00335.20 OQS07170.1 - 7.4e-24 84.7 11.7 8.9e-24 84.5 11.7 1.1 1 0 0 1 1 1 1 Tetraspanin family Ilm1 PF10311.9 OQS07170.1 - 0.1 12.2 0.7 0.36 10.5 0.7 1.9 1 1 0 1 1 1 0 Increased loss of mitochondrial DNA protein 1 SUR7 PF06687.12 OQS07170.1 - 0.55 9.8 7.4 0.46 10.1 2.1 2.4 1 1 1 2 2 2 0 SUR7/PalI family ABC2_membrane PF01061.24 OQS07172.1 - 7e-37 126.9 22.0 1e-36 126.3 22.0 1.3 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.27 OQS07172.1 - 2.3e-25 89.7 0.0 3.8e-25 89.0 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 OQS07172.1 - 1.8e-08 34.6 0.4 0.00074 19.4 0.0 2.2 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system ABC2_membrane_3 PF12698.7 OQS07172.1 - 7.4e-06 25.3 17.0 7.4e-06 25.3 17.0 1.7 2 0 0 2 2 2 1 ABC-2 family transporter protein RsgA_GTPase PF03193.16 OQS07172.1 - 9.6e-05 22.3 0.1 0.00018 21.4 0.1 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_16 PF13191.6 OQS07172.1 - 0.0013 19.1 0.0 0.0021 18.4 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain SMC_N PF02463.19 OQS07172.1 - 0.0032 17.0 0.1 0.23 10.9 0.1 2.2 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 OQS07172.1 - 0.0042 16.8 0.0 0.013 15.3 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_25 PF13481.6 OQS07172.1 - 0.049 13.2 0.1 0.29 10.7 0.0 2.1 3 0 0 3 3 3 0 AAA domain Dynamin_N PF00350.23 OQS07172.1 - 0.16 12.0 0.5 0.3 11.1 0.5 1.4 1 0 0 1 1 1 0 Dynamin family AAA_23 PF13476.6 OQS07172.1 - 0.2 12.1 0.0 0.36 11.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain PPTA PF01239.22 OQS07173.1 - 4.6e-45 150.1 14.1 5.5e-11 41.8 0.1 5.3 5 0 0 5 5 5 5 Protein prenyltransferase alpha subunit repeat PSCyt2 PF07583.11 OQS07173.1 - 0.028 14.3 0.5 0.068 13.1 0.5 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1549) NTP_transferase PF00483.23 OQS07174.1 - 7.2e-26 91.3 0.0 1e-25 90.8 0.0 1.2 1 0 0 1 1 1 1 Nucleotidyl transferase Hexapep PF00132.24 OQS07174.1 - 1.3e-08 34.2 10.1 5.5e-08 32.2 0.9 3.7 3 1 2 5 5 5 3 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.7 OQS07174.1 - 6.3e-06 26.6 0.0 9.3e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 MobA-like NTP transferase domain DUF4954 PF16314.5 OQS07174.1 - 0.0003 19.1 0.1 0.00042 18.6 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4954) CMD PF02627.20 OQS07175.1 - 3.8e-21 74.9 0.1 5.6e-21 74.4 0.1 1.3 1 0 0 1 1 1 1 Carboxymuconolactone decarboxylase family Aida_C2 PF14186.6 OQS07178.1 - 1.6e-23 83.0 0.0 3.4e-23 81.9 0.0 1.4 1 0 0 1 1 1 1 Cytoskeletal adhesion Ank_2 PF12796.7 OQS07178.1 - 2.2e-18 66.6 3.5 1.2e-07 32.2 0.1 3.6 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OQS07178.1 - 4.1e-16 58.8 3.1 8.2e-09 35.6 0.3 3.8 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 OQS07178.1 - 1.5e-13 50.5 0.9 0.0005 20.4 0.2 3.9 3 0 0 3 3 3 3 Ankyrin repeat Ank_4 PF13637.6 OQS07178.1 - 1.5e-13 50.9 4.5 0.00024 21.6 0.0 4.7 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQS07178.1 - 5.2e-12 44.8 4.6 0.0021 18.4 0.1 5.3 4 1 0 4 4 4 2 Ankyrin repeat IQ PF00612.27 OQS07178.1 - 1.1e-06 27.9 55.7 0.018 14.8 0.1 8.8 9 0 0 9 9 9 5 IQ calmodulin-binding motif PH PF00169.29 OQS07178.1 - 6.8e-06 26.5 0.0 1.6e-05 25.4 0.0 1.7 1 0 0 1 1 1 1 PH domain HK PF02110.15 OQS07178.1 - 0.13 11.6 0.1 2.8 7.3 0.0 2.2 2 0 0 2 2 2 0 Hydroxyethylthiazole kinase family Adaptin_N PF01602.20 OQS07179.1 - 1.6e-132 442.8 7.5 2e-132 442.4 7.5 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptinC2 PF02883.20 OQS07179.1 - 8.1e-20 71.2 0.0 1.5e-19 70.3 0.0 1.5 1 0 0 1 1 1 1 Adaptin C-terminal domain Cnd1 PF12717.7 OQS07179.1 - 2.3e-12 47.3 3.2 1.8e-05 24.8 0.1 2.8 1 1 1 2 2 2 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 OQS07179.1 - 4.2e-05 23.9 6.4 0.054 13.9 0.3 4.8 4 1 1 5 5 5 2 HEAT repeats HEAT PF02985.22 OQS07179.1 - 0.00011 22.1 0.4 0.24 11.8 0.0 4.8 4 0 0 4 4 4 1 HEAT repeat DUF5578 PF17741.1 OQS07179.1 - 0.066 12.6 0.4 38 3.6 0.0 3.2 3 0 0 3 3 3 0 Family of unknown function (DUF5578) CLASP_N PF12348.8 OQS07179.1 - 0.079 12.5 1.6 4.3 6.8 0.0 2.8 3 0 0 3 3 3 0 CLASP N terminal Vac14_Fab1_bd PF12755.7 OQS07179.1 - 0.083 13.5 2.1 1.7 9.3 0.0 3.6 3 1 1 4 4 4 0 Vacuolar 14 Fab1-binding region MOR2-PAG1_N PF14222.6 OQS07179.1 - 0.097 11.6 0.0 0.22 10.5 0.0 1.6 1 0 0 1 1 1 0 Cell morphogenesis N-terminal V-ATPase_H_C PF11698.8 OQS07179.1 - 0.14 12.3 0.1 22 5.2 0.0 3.0 1 1 1 2 2 2 0 V-ATPase subunit H Homeodomain PF00046.29 OQS07180.1 - 8.7e-05 22.3 0.4 8.7e-05 22.3 0.4 2.0 2 0 0 2 2 2 1 Homeodomain PerC PF06069.11 OQS07180.1 - 0.09 13.0 0.2 0.19 12.0 0.2 1.5 1 0 0 1 1 1 0 PerC transcriptional activator 4HBT_2 PF13279.6 OQS07181.1 - 7.1e-23 81.4 0.0 9.5e-23 81.0 0.0 1.2 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl-ACP_TE PF01643.17 OQS07181.1 - 0.0049 16.2 0.0 0.0082 15.5 0.0 1.3 1 0 0 1 1 1 1 Acyl-ACP thioesterase Peptidase_C33 PF05412.12 OQS07181.1 - 0.17 11.9 0.1 1.1 9.4 0.0 2.1 2 0 0 2 2 2 0 Equine arterivirus Nsp2-type cysteine proteinase BRO1 PF03097.18 OQS07182.1 - 6.8e-107 357.6 6.7 6.8e-107 357.6 6.7 1.9 2 0 0 2 2 2 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.6 OQS07182.1 - 4.2e-48 164.1 11.7 7.5e-48 163.3 10.0 2.2 2 0 0 2 2 2 1 ALIX V-shaped domain binding to HIV Pkinase PF00069.25 OQS07183.1 - 1.8e-61 207.8 0.0 2.1e-61 207.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQS07183.1 - 1.4e-40 139.2 0.0 1.7e-40 138.9 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OQS07183.1 - 3.1e-05 23.4 0.0 0.00011 21.6 0.0 1.7 1 1 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 OQS07183.1 - 0.00053 18.9 0.0 0.00072 18.4 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase PCI PF01399.27 OQS07184.1 - 3.2e-12 46.9 2.1 3.3e-12 46.8 0.1 2.1 3 0 0 3 3 3 1 PCI domain ANAPC4_WD40 PF12894.7 OQS07185.1 - 1.6e-10 41.2 2.4 1.1e-05 25.6 0.1 5.3 4 2 2 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain Clathrin PF00637.20 OQS07185.1 - 1.1e-07 31.8 13.7 0.13 12.1 0.5 6.8 4 2 2 6 6 6 2 Region in Clathrin and VPS WD40 PF00400.32 OQS07185.1 - 2.2e-06 28.3 0.9 11 7.1 0.0 6.0 6 1 0 6 6 5 1 WD domain, G-beta repeat Coatomer_WDAD PF04053.14 OQS07185.1 - 0.00038 19.6 12.5 0.048 12.7 0.8 4.6 4 0 0 4 4 4 2 Coatomer WD associated region TPR_14 PF13428.6 OQS07185.1 - 0.018 15.8 21.9 0.82 10.7 0.0 8.8 9 1 0 9 9 9 0 Tetratricopeptide repeat STAT_int PF02865.17 OQS07185.1 - 0.074 13.5 0.5 3.7 8.0 0.3 2.7 2 0 0 2 2 2 0 STAT protein, protein interaction domain RICTOR_M PF14666.6 OQS07185.1 - 0.11 12.3 0.0 0.28 11.0 0.0 1.6 1 0 0 1 1 1 0 Rapamycin-insensitive companion of mTOR, middle domain TAT_ubiq PF07706.12 OQS07185.1 - 0.14 12.4 0.0 15 5.9 0.0 2.5 2 0 0 2 2 2 0 Aminotransferase ubiquitination site TPR_2 PF07719.17 OQS07185.1 - 0.4 10.9 32.1 4.2 7.7 0.2 8.4 10 0 0 10 10 9 0 Tetratricopeptide repeat MIT PF04212.18 OQS07185.1 - 0.93 9.6 14.1 0.84 9.7 0.1 5.6 6 0 0 6 6 5 0 MIT (microtubule interacting and transport) domain ANAPC3 PF12895.7 OQS07185.1 - 3.3 8.0 23.0 0.41 10.9 0.1 7.5 7 2 2 9 9 9 0 Anaphase-promoting complex, cyclosome, subunit 3 Mad3_BUB1_I PF08311.12 OQS07185.1 - 5.1 7.1 7.5 56 3.7 0.1 4.6 5 0 0 5 5 5 0 Mad3/BUB1 homology region 1 Ribosomal_L7Ae PF01248.26 OQS07186.1 - 1.8e-08 34.0 0.0 2.7e-08 33.5 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Ax_dynein_light PF10211.9 OQS07187.1 - 1e-60 204.9 4.0 1.2e-60 204.6 4.0 1.0 1 0 0 1 1 1 1 Axonemal dynein light chain Herpes_BLRF2 PF05812.12 OQS07187.1 - 0.13 12.4 1.3 0.26 11.4 1.3 1.5 1 0 0 1 1 1 0 Herpesvirus BLRF2 protein NYD-SP28_assoc PF14775.6 OQS07187.1 - 0.13 12.4 11.5 1.7 8.8 4.3 2.7 1 1 1 2 2 2 0 Sperm tail C-terminal domain bZIP_1 PF00170.21 OQS07187.1 - 0.16 12.1 3.1 0.17 12.0 1.8 1.8 1 1 0 1 1 1 0 bZIP transcription factor Occludin_ELL PF07303.13 OQS07187.1 - 0.32 11.7 5.7 0.32 11.8 4.2 1.6 2 0 0 2 2 2 0 Occludin homology domain DivIC PF04977.15 OQS07187.1 - 8.1 6.3 8.4 0.41 10.4 1.1 2.3 2 1 1 3 3 3 0 Septum formation initiator DUF2353 PF09789.9 OQS07188.1 - 0.015 14.7 29.1 0.015 14.6 22.0 2.3 1 1 1 2 2 2 0 Uncharacterized coiled-coil protein (DUF2353) HOOK PF05622.12 OQS07188.1 - 0.11 10.7 39.4 0.56 8.3 39.4 2.1 1 1 0 1 1 1 0 HOOK protein Seryl_tRNA_N PF02403.22 OQS07188.1 - 0.25 11.6 38.3 0.099 12.9 9.4 4.1 1 1 2 3 3 3 0 Seryl-tRNA synthetase N-terminal domain Atg14 PF10186.9 OQS07188.1 - 0.53 9.3 33.8 0.18 10.9 25.8 2.7 1 1 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 LPP PF04728.13 OQS07188.1 - 0.69 10.3 30.5 3.2 8.2 0.3 7.2 3 2 2 6 6 6 0 Lipoprotein leucine-zipper Tropomyosin_1 PF12718.7 OQS07188.1 - 0.86 9.8 46.7 0.92 9.7 30.3 3.4 2 1 2 4 4 4 0 Tropomyosin like GAS PF13851.6 OQS07188.1 - 0.95 8.8 46.9 1.7 7.9 14.3 3.7 2 1 2 4 4 4 0 Growth-arrest specific micro-tubule binding FlaC_arch PF05377.11 OQS07188.1 - 1 9.8 31.0 1.9 8.9 2.7 6.4 6 1 2 8 8 7 0 Flagella accessory protein C (FlaC) DUF3584 PF12128.8 OQS07188.1 - 1 6.8 34.5 1.6 6.2 34.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF812 PF05667.11 OQS07188.1 - 1.3 7.8 33.0 2.8 6.7 33.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF812) KLRAQ PF10205.9 OQS07188.1 - 2.1 8.6 35.9 2.4 8.4 13.5 4.2 1 1 3 4 4 4 0 Predicted coiled-coil domain-containing protein TMF_TATA_bd PF12325.8 OQS07188.1 - 7.6 6.8 38.7 0.49 10.6 6.5 4.3 2 1 3 5 5 5 0 TATA element modulatory factor 1 TATA binding FapA PF03961.13 OQS07188.1 - 7.7 5.0 27.7 4.1 5.9 8.8 2.4 1 1 1 2 2 2 0 Flagellar Assembly Protein A ADIP PF11559.8 OQS07188.1 - 8 6.5 40.9 0.6 10.2 12.6 4.3 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding TRP PF06011.12 OQS07189.1 - 8.7e-05 21.4 5.4 8.7e-05 21.4 5.4 2.2 3 0 0 3 3 3 1 Transient receptor potential (TRP) ion channel DUF4668 PF15701.5 OQS07189.1 - 0.0083 16.0 3.2 1.8 8.4 0.5 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF4668) Asp_Arg_Hydrox PF05118.15 OQS07190.1 - 2.7e-45 154.0 0.1 7.2e-45 152.6 0.0 1.8 2 0 0 2 2 2 1 Aspartyl/Asparaginyl beta-hydroxylase DUSP PF06337.12 OQS07190.1 - 2.4e-05 24.9 0.0 0.0001 22.8 0.0 2.2 2 1 0 2 2 2 1 DUSP domain Proteasome PF00227.26 OQS07191.1 - 6.9e-45 152.9 0.0 8.6e-45 152.6 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 OQS07191.1 - 1.1e-12 47.3 0.1 1.9e-12 46.6 0.1 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature IQ PF00612.27 OQS07193.1 - 4.6e-07 29.1 21.0 0.0091 15.7 0.1 4.9 5 0 0 5 5 5 4 IQ calmodulin-binding motif Beta_helix PF13229.6 OQS07194.1 - 0.015 15.1 3.3 0.024 14.5 3.3 1.2 1 0 0 1 1 1 0 Right handed beta helix region Chlam_PMP PF02415.17 OQS07194.1 - 0.089 13.3 17.8 2.6 8.7 1.5 4.7 4 0 0 4 4 4 0 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat LRR_6 PF13516.6 OQS07195.1 - 1.7e-08 33.8 10.9 0.0082 16.1 0.0 5.4 5 0 0 5 5 5 3 Leucine Rich repeat LRR_4 PF12799.7 OQS07195.1 - 0.011 16.1 16.9 0.091 13.2 0.1 5.4 5 2 1 6 6 6 0 Leucine Rich repeats (2 copies) Phage_CRI PF05144.14 OQS07195.1 - 0.021 14.2 0.2 2.1 7.6 0.0 2.2 2 0 0 2 2 2 0 Phage replication protein CRI LRR_1 PF00560.33 OQS07195.1 - 0.071 13.7 5.6 14 6.7 0.0 5.4 5 0 0 5 5 5 0 Leucine Rich Repeat LRR_12 PF18837.1 OQS07195.1 - 0.57 9.9 0.0 0.57 9.9 0.0 2.6 3 0 0 3 3 3 0 Leucine-rich repeat LRR_8 PF13855.6 OQS07195.1 - 1.3 8.8 16.7 9.3 6.1 0.6 5.1 4 2 0 4 4 4 0 Leucine rich repeat AAA PF00004.29 OQS07196.1 - 1.6e-37 128.8 0.2 7.1e-37 126.8 0.1 2.2 2 1 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) MIT PF04212.18 OQS07196.1 - 3.8e-12 46.1 0.8 8.6e-12 45.0 0.8 1.6 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain AAA_lid_3 PF17862.1 OQS07196.1 - 6.9e-12 45.0 0.0 1.1e-10 41.2 0.0 2.4 1 1 0 1 1 1 1 AAA+ lid domain Vps4_C PF09336.10 OQS07196.1 - 4.6e-06 26.5 0.0 3.3e-05 23.8 0.0 2.4 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain AAA_5 PF07728.14 OQS07196.1 - 6.3e-06 26.2 0.0 1.7e-05 24.8 0.0 1.8 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 OQS07196.1 - 8.9e-05 22.8 0.7 0.00065 20.0 0.2 2.5 2 1 0 2 2 2 1 AAA domain NACHT PF05729.12 OQS07196.1 - 0.00027 20.9 0.0 0.0011 18.9 0.0 2.0 2 0 0 2 2 2 1 NACHT domain AAA_16 PF13191.6 OQS07196.1 - 0.00029 21.2 0.5 0.016 15.6 0.2 3.1 1 1 0 2 2 2 1 AAA ATPase domain AAA_2 PF07724.14 OQS07196.1 - 0.0025 17.9 0.0 0.0045 17.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_33 PF13671.6 OQS07196.1 - 0.0033 17.6 0.0 0.0067 16.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.12 OQS07196.1 - 0.0037 17.0 0.0 0.014 15.1 0.0 1.9 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain IstB_IS21 PF01695.17 OQS07196.1 - 0.0056 16.4 0.2 0.019 14.7 0.0 1.9 2 0 0 2 2 2 1 IstB-like ATP binding protein Mg_chelatase PF01078.21 OQS07196.1 - 0.0069 15.8 0.2 0.015 14.7 0.2 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.26 OQS07196.1 - 0.013 15.2 0.0 0.41 10.3 0.0 2.4 2 1 0 2 2 2 0 Sigma-54 interaction domain AAA_25 PF13481.6 OQS07196.1 - 0.015 14.9 0.1 0.12 11.9 0.1 2.1 2 0 0 2 2 2 0 AAA domain TniB PF05621.11 OQS07196.1 - 0.022 14.2 0.2 3.2 7.1 0.1 3.0 2 1 0 2 2 2 0 Bacterial TniB protein AAA_18 PF13238.6 OQS07196.1 - 0.034 14.7 0.4 0.16 12.5 0.4 2.1 1 1 0 1 1 1 0 AAA domain AAA_7 PF12775.7 OQS07196.1 - 0.036 13.6 0.0 0.069 12.7 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_24 PF13479.6 OQS07196.1 - 0.042 13.6 0.1 0.1 12.3 0.0 1.7 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 OQS07196.1 - 0.084 13.3 0.1 0.25 11.8 0.1 1.9 1 1 0 1 1 1 0 RNA helicase Parvo_NS1 PF01057.17 OQS07196.1 - 0.099 11.7 0.0 0.21 10.7 0.0 1.4 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_14 PF13173.6 OQS07196.1 - 0.12 12.4 0.0 0.32 11.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain DUF778 PF05608.12 OQS07197.1 - 3.7e-33 115.5 1.2 1.7e-19 70.9 0.2 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF778) TMEM107 PF14995.6 OQS07198.1 - 0.89 10.0 12.7 4 7.9 12.7 2.3 1 1 0 1 1 1 0 Transmembrane protein Phage_holin_3_6 PF07332.11 OQS07198.1 - 2.1 8.4 5.5 23 5.1 0.2 2.8 3 0 0 3 3 3 0 Putative Actinobacterial Holin-X, holin superfamily III SHR3_chaperone PF08229.11 OQS07198.1 - 5.6 5.9 7.7 0.42 9.6 0.8 2.2 2 0 0 2 2 2 0 ER membrane protein SH3 DNA_primase_lrg PF04104.14 OQS07199.1 - 2.4e-75 253.4 0.0 4.3e-75 252.5 0.0 1.4 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase, large subunit Arf PF00025.21 OQS07200.1 - 1.2e-19 70.4 0.1 2.6e-19 69.3 0.1 1.5 1 0 0 1 1 1 1 ADP-ribosylation factor family TPR_16 PF13432.6 OQS07200.1 - 1.2e-12 48.3 50.3 0.00018 22.1 1.7 11.7 10 2 1 11 11 11 4 Tetratricopeptide repeat TPR_2 PF07719.17 OQS07200.1 - 1.6e-10 40.3 48.4 0.63 10.3 0.0 16.5 17 1 1 18 18 17 3 Tetratricopeptide repeat TPR_17 PF13431.6 OQS07200.1 - 1.9e-10 40.4 36.8 0.033 14.6 0.0 14.2 17 0 0 17 17 14 3 Tetratricopeptide repeat TPR_1 PF00515.28 OQS07200.1 - 1.6e-09 37.1 46.4 1.8 8.5 0.0 15.8 18 1 1 19 19 19 4 Tetratricopeptide repeat TPR_14 PF13428.6 OQS07200.1 - 3.3e-09 36.8 52.1 0.47 11.4 0.3 17.9 15 7 5 21 21 19 3 Tetratricopeptide repeat TPR_11 PF13414.6 OQS07200.1 - 7e-09 35.2 25.7 1.2 8.9 0.1 11.2 13 0 0 13 13 12 3 TPR repeat TPR_8 PF13181.6 OQS07200.1 - 8.8e-07 28.7 38.1 0.88 9.9 0.2 13.7 14 0 0 14 14 13 2 Tetratricopeptide repeat TPR_19 PF14559.6 OQS07200.1 - 3.1e-05 24.4 34.3 0.26 11.8 0.2 9.9 9 2 1 10 10 8 3 Tetratricopeptide repeat RRM_1 PF00076.22 OQS07200.1 - 3.9e-05 23.4 0.0 0.012 15.4 0.0 2.7 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Roc PF08477.13 OQS07200.1 - 0.015 15.5 0.0 0.04 14.1 0.0 1.7 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase Limkain-b1 PF11608.8 OQS07200.1 - 0.022 14.8 0.1 11 6.2 0.0 2.9 2 0 0 2 2 2 0 Limkain b1 ANAPC3 PF12895.7 OQS07200.1 - 0.034 14.4 31.8 1.5 9.1 0.1 8.9 7 2 2 9 9 8 0 Anaphase-promoting complex, cyclosome, subunit 3 SRPRB PF09439.10 OQS07200.1 - 0.087 12.2 0.2 0.32 10.4 0.1 1.9 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit Ras PF00071.22 OQS07200.1 - 0.12 11.9 0.1 0.26 10.9 0.1 1.5 1 0 0 1 1 1 0 Ras family SRP_TPR_like PF17004.5 OQS07200.1 - 2.3 8.3 5.6 1.1 9.3 0.3 3.1 3 0 0 3 3 3 0 Putative TPR-like repeat TPR_7 PF13176.6 OQS07200.1 - 2.4 8.4 14.0 28 5.0 0.2 8.1 9 1 1 10 10 9 0 Tetratricopeptide repeat TPR_20 PF14561.6 OQS07200.1 - 5.1 7.5 11.5 5.7 7.4 0.0 5.7 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_12 PF13424.6 OQS07200.1 - 6.2 7.2 51.0 0.34 11.2 1.0 12.0 10 4 2 12 12 11 0 Tetratricopeptide repeat Ribonuc_P_40 PF08584.11 OQS07201.1 - 1.8e-45 155.5 0.0 2.2e-45 155.1 0.0 1.0 1 0 0 1 1 1 1 Ribonuclease P 40kDa (Rpp40) subunit DUF1251 PF06856.11 OQS07201.1 - 0.015 15.0 0.0 0.028 14.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1251) BLM10_mid PF16507.5 OQS07203.1 - 1.2e-47 162.8 0.0 4.9e-47 160.8 0.0 1.9 1 1 0 1 1 1 1 Proteasome-substrate-size regulator, mid region Pkinase PF00069.25 OQS07204.1 - 1.7e-38 132.5 0.1 2.5e-38 132.0 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQS07204.1 - 2.7e-23 82.6 0.1 3.5e-23 82.2 0.1 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OQS07204.1 - 1.8e-11 43.9 0.1 1.8e-09 37.3 0.0 2.1 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.14 OQS07204.1 - 0.0015 18.0 0.2 0.0032 16.8 0.2 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Ank_2 PF12796.7 OQS07205.1 - 6.6e-33 113.2 5.9 2.6e-16 60.0 0.3 3.0 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQS07205.1 - 2.7e-21 75.6 0.9 3.5e-07 30.7 0.0 3.2 3 0 0 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 OQS07205.1 - 3.4e-18 65.2 11.4 0.00029 21.1 0.0 4.9 4 1 1 5 5 5 4 Ankyrin repeat Ank_3 PF13606.6 OQS07205.1 - 1.4e-17 61.9 0.4 0.0021 18.4 0.1 5.2 5 0 0 5 5 5 4 Ankyrin repeat Ank_5 PF13857.6 OQS07205.1 - 0.00076 19.7 0.4 1.6 9.2 0.0 3.6 4 0 0 4 4 4 1 Ankyrin repeats (many copies) CholecysA-Rec_N PF09193.10 OQS07205.1 - 0.0037 17.2 1.6 16 5.6 0.0 3.7 4 0 0 4 4 4 1 Cholecystokinin A receptor, N-terminal MetallophosN PF16371.5 OQS07205.1 - 0.024 14.9 0.0 4 7.8 0.0 2.4 1 1 1 2 2 2 0 N terminal of Calcineurin-like phosphoesterase TM1506 PF08973.10 OQS07205.1 - 0.11 12.2 0.0 3.1 7.5 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1893) Ank_2 PF12796.7 OQS07206.1 - 4.1e-115 376.6 35.2 1.9e-15 57.2 0.5 10.8 4 3 6 10 10 10 10 Ankyrin repeats (3 copies) Ank PF00023.30 OQS07206.1 - 2.6e-98 318.6 58.6 7.6e-09 35.6 0.1 19.6 19 1 1 20 20 19 16 Ankyrin repeat Ank_4 PF13637.6 OQS07206.1 - 1.4e-92 303.0 27.5 6e-11 42.7 0.0 15.9 6 4 9 16 16 16 15 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQS07206.1 - 1.9e-82 261.3 32.3 6.3e-05 23.1 0.4 20.5 20 0 0 20 20 20 16 Ankyrin repeat Pkinase_Tyr PF07714.17 OQS07206.1 - 3.1e-80 269.2 0.0 1e-43 149.5 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 OQS07206.1 - 4.5e-79 265.5 0.0 2.1e-45 155.2 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Ank_5 PF13857.6 OQS07206.1 - 1.5e-63 210.0 38.9 1.5e-07 31.5 0.6 15.3 7 3 10 18 18 18 16 Ankyrin repeats (many copies) Haspin_kinase PF12330.8 OQS07206.1 - 4.8e-05 22.5 1.5 0.15 11.0 0.1 3.3 2 1 0 2 2 2 2 Haspin like kinase domain Imm_superinfect PF14373.6 OQS07206.1 - 0.026 14.4 4.0 13 5.8 0.0 5.9 7 0 0 7 7 7 0 Superinfection immunity protein Kdo PF06293.14 OQS07206.1 - 0.027 13.8 0.4 3.6 6.9 0.1 2.3 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family ABC1 PF03109.16 OQS07206.1 - 0.067 13.4 0.0 0.62 10.2 0.0 2.5 2 0 0 2 2 2 0 ABC1 family Kinase-like PF14531.6 OQS07206.1 - 0.072 12.4 0.0 0.27 10.5 0.0 1.9 2 0 0 2 2 2 0 Kinase-like Arg_repressor PF01316.21 OQS07206.1 - 0.084 12.6 0.8 39 4.1 0.0 4.4 4 0 0 4 4 4 0 Arginine repressor, DNA binding domain Pkinase_fungal PF17667.1 OQS07206.1 - 0.14 10.9 0.0 0.27 9.9 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase NUDIX PF00293.28 OQS07207.1 - 8.2e-13 48.5 0.0 1.2e-12 48.0 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain Ank_2 PF12796.7 OQS07208.1 - 4.7e-12 46.3 0.0 3.6e-11 43.5 0.0 1.9 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQS07208.1 - 1.5e-11 44.6 0.1 1.6e-08 34.9 0.0 1.9 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 OQS07208.1 - 6.5e-11 42.2 1.2 2.8e-06 27.5 0.0 2.1 2 0 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.6 OQS07208.1 - 6.8e-11 41.4 0.0 9.6e-06 25.6 0.0 2.2 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.6 OQS07208.1 - 2.8e-06 27.5 0.1 0.0036 17.6 0.0 2.1 1 1 1 2 2 2 2 Ankyrin repeats (many copies) YfmQ PF10787.9 OQS07208.1 - 0.081 12.7 0.0 0.27 11.0 0.0 1.7 1 1 1 2 2 2 0 Uncharacterised protein from bacillus cereus group TPT PF03151.16 OQS07209.1 - 8.7e-33 113.9 22.7 1.3e-32 113.3 22.7 1.3 1 0 0 1 1 1 1 Triose-phosphate Transporter family UAA PF08449.11 OQS07209.1 - 1.2e-08 34.5 20.8 1.2e-08 34.5 20.8 1.6 1 1 0 1 1 1 1 UAA transporter family EamA PF00892.20 OQS07209.1 - 6.4e-06 26.4 37.6 4.2e-05 23.7 14.1 2.7 2 1 0 2 2 2 2 EamA-like transporter family PUNUT PF16913.5 OQS07209.1 - 1.4e-05 24.5 23.3 2.3e-05 23.8 23.3 1.4 1 0 0 1 1 1 1 Purine nucleobase transmembrane transport RNA_pol_Rpc4 PF05132.14 OQS07210.1 - 1.5e-21 77.4 3.6 5.5e-20 72.3 0.2 3.0 2 1 0 2 2 2 1 RNA polymerase III RPC4 API5 PF05918.11 OQS07210.1 - 2.5 6.8 4.1 3.3 6.4 4.1 1.1 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) Ras PF00071.22 OQS07211.1 - 1.9e-15 56.8 0.0 2.4e-15 56.5 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OQS07211.1 - 7.1e-12 45.6 0.0 1e-11 45.1 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 OQS07211.1 - 6.4e-06 26.2 0.0 8.4e-06 25.9 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Arf PF00025.21 OQS07211.1 - 0.00023 20.6 0.0 0.00034 20.1 0.0 1.3 1 1 0 1 1 1 1 ADP-ribosylation factor family FeoB_N PF02421.18 OQS07211.1 - 0.00078 19.0 0.0 0.0013 18.3 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B Gtr1_RagA PF04670.12 OQS07211.1 - 0.0023 17.4 0.0 0.0028 17.1 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 OQS07211.1 - 0.044 13.2 0.0 0.058 12.8 0.0 1.1 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit RNase_Zc3h12a PF11977.8 OQS07212.1 - 3.7e-19 69.0 0.2 3.7e-19 69.0 0.2 1.7 2 0 0 2 2 2 1 Zc3h12a-like Ribonuclease NYN domain DUF4411 PF14367.6 OQS07212.1 - 0.021 14.8 0.2 0.21 11.5 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4411) DNA_pol3_beta_3 PF02768.15 OQS07212.1 - 0.037 13.9 0.0 0.067 13.0 0.0 1.4 1 0 0 1 1 1 0 DNA polymerase III beta subunit, C-terminal domain WD40 PF00400.32 OQS07213.1 - 3.4e-06 27.7 8.8 0.073 14.0 0.1 4.8 4 1 0 4 4 4 3 WD domain, G-beta repeat DnaJ PF00226.31 OQS07214.1 - 6.3e-14 51.8 1.6 1e-13 51.1 0.1 2.3 2 0 0 2 2 2 1 DnaJ domain TPR_1 PF00515.28 OQS07214.1 - 6.4e-08 32.1 6.9 0.00091 19.0 0.6 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.6 OQS07214.1 - 1.3e-05 24.7 2.1 7.7e-05 22.3 0.4 2.8 3 0 0 3 3 3 1 TPR repeat TPR_2 PF07719.17 OQS07214.1 - 1.4e-05 24.8 12.2 0.0019 18.2 0.5 4.8 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_17 PF13431.6 OQS07214.1 - 2.8e-05 24.2 0.5 0.045 14.2 0.2 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 OQS07214.1 - 0.0032 18.1 0.1 0.0032 18.1 0.1 3.1 2 1 2 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.6 OQS07214.1 - 0.019 15.8 3.1 6.6 7.8 0.0 3.8 1 1 2 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 OQS07214.1 - 0.26 11.6 6.4 5.9 7.3 0.1 3.8 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_8 PF13181.6 OQS07214.1 - 0.31 11.4 7.1 37 4.9 0.1 5.2 3 1 2 5 5 5 0 Tetratricopeptide repeat Uteroglobin PF01099.17 OQS07214.1 - 0.69 10.3 3.0 4.5 7.7 0.1 2.9 2 1 0 2 2 2 0 Uteroglobin family PDEase_I PF00233.19 OQS07215.1 - 1.4e-17 64.2 0.0 7.4e-17 61.9 0.0 1.8 2 0 0 2 2 2 1 3'5'-cyclic nucleotide phosphodiesterase Aldo_ket_red PF00248.21 OQS07216.1 - 0.014 14.6 0.0 0.027 13.7 0.0 1.4 1 0 0 1 1 1 0 Aldo/keto reductase family Band_7 PF01145.25 OQS07216.1 - 0.34 10.9 3.5 1.5 8.8 0.1 2.4 2 0 0 2 2 2 0 SPFH domain / Band 7 family ATP-cone PF03477.16 OQS07216.1 - 0.9 10.2 3.0 0.88 10.2 0.1 2.2 2 0 0 2 2 2 0 ATP cone domain Pkinase PF00069.25 OQS07217.1 - 1.8e-42 145.6 0.0 5.1e-42 144.1 0.0 1.9 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQS07217.1 - 2.2e-39 135.3 0.0 7.2e-39 133.6 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase Ank_2 PF12796.7 OQS07217.1 - 3.5e-32 110.8 5.6 1.6e-13 51.0 0.4 3.8 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQS07217.1 - 5.3e-30 103.4 0.4 4.6e-08 33.5 0.0 5.6 3 1 2 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQS07217.1 - 1.3e-14 52.9 2.1 0.0023 18.3 0.0 7.2 7 0 0 7 7 7 2 Ankyrin repeat Ank PF00023.30 OQS07217.1 - 3.6e-14 52.5 5.2 0.00046 20.5 0.0 6.6 7 0 0 7 7 6 3 Ankyrin repeat Ank_5 PF13857.6 OQS07217.1 - 2.2e-13 50.1 2.3 0.00041 20.6 0.0 5.4 1 1 3 5 5 5 2 Ankyrin repeats (many copies) Dzip-like_N PF13815.6 OQS07217.1 - 3.1e-09 36.8 3.3 3.1e-09 36.8 3.3 3.9 3 1 0 3 3 3 1 Iguana/Dzip1-like DAZ-interacting protein N-terminal Kdo PF06293.14 OQS07217.1 - 8.6e-05 22.0 0.1 0.00034 20.0 0.0 1.9 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family zf-C2H2 PF00096.26 OQS07217.1 - 0.0045 17.4 0.7 0.015 15.7 0.7 2.0 1 0 0 1 1 1 1 Zinc finger, C2H2 type FTA2 PF13095.6 OQS07217.1 - 0.011 15.3 0.0 0.14 11.7 0.0 2.6 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 zf-C2H2_4 PF13894.6 OQS07217.1 - 0.02 15.7 0.8 0.064 14.1 0.8 2.0 1 0 0 1 1 1 0 C2H2-type zinc finger ARS2 PF04959.13 OQS07217.1 - 0.046 14.1 0.3 0.22 11.9 0.2 2.2 1 1 1 2 2 2 0 Arsenite-resistance protein 2 V-SNARE PF05008.15 OQS07217.1 - 0.94 9.9 10.8 0.33 11.4 0.4 3.9 2 1 1 3 3 3 0 Vesicle transport v-SNARE protein N-terminus zf-C2H2_3rep PF18868.1 OQS07217.1 - 1.1 10.0 5.2 0.31 11.7 0.1 2.7 2 0 0 2 2 2 0 Zinc finger C2H2-type, 3 repeats DASH_Duo1 PF08651.10 OQS07217.1 - 3.5 7.5 14.4 1.1 9.1 0.6 5.0 5 0 0 5 5 5 0 DASH complex subunit Duo1 EF-hand_7 PF13499.6 OQS07218.1 - 1.3e-38 131.3 12.7 8.8e-16 58.1 0.4 4.5 4 1 1 5 5 5 4 EF-hand domain pair EF-hand_1 PF00036.32 OQS07218.1 - 4.1e-36 119.8 24.0 1.3e-07 30.6 1.0 7.1 7 0 0 7 7 7 6 EF hand EF-hand_6 PF13405.6 OQS07218.1 - 5.3e-29 97.6 16.4 7.4e-06 25.5 0.1 6.6 7 0 0 7 7 7 6 EF-hand domain EF-hand_8 PF13833.6 OQS07218.1 - 1.6e-25 88.7 19.8 1.6e-08 34.3 0.6 6.4 4 2 2 6 6 6 6 EF-hand domain pair EF-hand_5 PF13202.6 OQS07218.1 - 2.7e-23 80.4 17.8 1.5e-05 24.3 0.5 6.3 6 0 0 6 6 6 6 EF hand C2 PF00168.30 OQS07218.1 - 6.8e-17 61.6 0.0 2.4e-16 59.9 0.0 1.8 2 0 0 2 2 2 1 C2 domain EF-hand_9 PF14658.6 OQS07218.1 - 1.2e-09 38.3 0.7 0.04 14.2 0.0 3.8 3 1 1 4 4 4 3 EF-hand domain SPARC_Ca_bdg PF10591.9 OQS07218.1 - 3.9e-09 36.8 0.6 0.3 11.4 0.0 3.2 3 0 0 3 3 3 3 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 OQS07218.1 - 3.1e-07 30.3 4.9 0.34 10.9 0.1 4.2 3 1 1 4 4 4 2 Cytoskeletal-regulatory complex EF hand bZIP_2 PF07716.15 OQS07219.1 - 2.2e-05 24.4 0.5 7.3e-05 22.8 0.5 1.9 1 0 0 1 1 1 1 Basic region leucine zipper CCDC92 PF14916.6 OQS07219.1 - 0.018 14.8 6.5 0.088 12.6 0.9 3.1 3 0 0 3 3 3 0 Coiled-coil domain of unknown function YedD PF13987.6 OQS07219.1 - 0.15 11.9 1.1 0.39 10.6 0.7 1.9 2 0 0 2 2 2 0 YedD-like protein FGE-sulfatase PF03781.16 OQS07220.1 - 2.5e-24 86.3 0.0 4.4e-24 85.5 0.0 1.4 1 0 0 1 1 1 1 Sulfatase-modifying factor enzyme 1 TMEM154 PF15102.6 OQS07221.1 - 0.00092 19.1 18.4 0.0032 17.4 0.1 3.9 3 1 1 4 4 4 2 TMEM154 protein family EphA2_TM PF14575.6 OQS07221.1 - 0.013 16.4 0.0 4.4 8.2 0.0 2.6 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Orthoreo_P10 PF07204.11 OQS07221.1 - 0.014 15.3 0.0 0.63 10.0 0.0 2.3 2 0 0 2 2 2 0 Orthoreovirus membrane fusion protein p10 DUF5305 PF17231.2 OQS07221.1 - 0.02 14.3 2.4 0.77 9.1 0.2 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5305) LRR19-TM PF15176.6 OQS07221.1 - 0.1 12.6 0.1 0.33 11.0 0.1 1.8 1 0 0 1 1 1 0 Leucine-rich repeat family 19 TM domain DAP10 PF07213.11 OQS07221.1 - 0.11 12.5 0.0 11 6.0 0.0 2.9 3 0 0 3 3 3 0 DAP10 membrane protein Ank_2 PF12796.7 OQS07222.1 - 2.9e-25 88.7 22.4 4.2e-06 27.3 0.7 7.4 2 2 5 8 8 8 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQS07222.1 - 6.7e-13 48.9 23.2 0.004 17.7 0.1 9.2 8 2 3 11 11 11 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 OQS07222.1 - 3.1e-09 36.9 20.8 2.2 8.7 0.0 11.8 5 3 8 14 14 14 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQS07222.1 - 9.4e-05 22.5 20.1 29 5.7 0.0 11.2 13 1 1 14 14 14 0 Ankyrin repeat Mur_ligase_M PF08245.12 OQS07222.1 - 0.0018 18.3 0.1 0.016 15.2 0.0 2.3 1 1 1 2 2 2 1 Mur ligase middle domain Ank PF00023.30 OQS07222.1 - 0.0037 17.7 13.1 7.8 7.1 0.1 8.2 4 2 3 7 7 7 1 Ankyrin repeat Mur_ligase_C PF02875.21 OQS07222.1 - 0.024 14.9 0.0 0.055 13.7 0.0 1.6 1 0 0 1 1 1 0 Mur ligase family, glutamate ligase domain CHAT PF12770.7 OQS07223.1 - 9.6e-12 44.9 0.2 2.2e-11 43.7 0.2 1.5 1 0 0 1 1 1 1 CHAT domain NACHT PF05729.12 OQS07223.1 - 1e-08 35.3 0.0 2.9e-08 33.8 0.0 1.8 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 OQS07223.1 - 3.6e-08 34.0 0.0 8.7e-08 32.7 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain SH2 PF00017.24 OQS07223.1 - 3.4e-06 27.1 0.0 6.9e-06 26.1 0.0 1.5 1 0 0 1 1 1 1 SH2 domain AAA_22 PF13401.6 OQS07223.1 - 8.2e-05 22.9 0.0 0.00021 21.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain ATPase_2 PF01637.18 OQS07223.1 - 9.6e-05 22.4 0.0 0.00018 21.5 0.0 1.4 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea AAA PF00004.29 OQS07223.1 - 0.00028 21.3 0.0 0.00072 20.0 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 OQS07223.1 - 0.0015 18.1 0.0 0.0032 17.0 0.0 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region PhoH PF02562.16 OQS07223.1 - 0.0068 15.9 0.0 0.011 15.1 0.0 1.3 1 0 0 1 1 1 1 PhoH-like protein Peptidase_C14 PF00656.22 OQS07223.1 - 0.011 15.7 0.0 0.045 13.7 0.0 1.9 2 0 0 2 2 2 0 Caspase domain NB-ARC PF00931.22 OQS07223.1 - 0.054 12.7 0.0 0.1 11.7 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain AAA_30 PF13604.6 OQS07223.1 - 0.18 11.5 0.0 0.35 10.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 OQS07223.1 - 0.19 11.5 0.0 0.44 10.3 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein DUF2561 PF10812.8 OQS07224.1 - 0.00046 20.3 0.1 0.00046 20.3 0.1 2.2 3 0 0 3 3 3 1 Protein of unknown function (DUF2561) EphA2_TM PF14575.6 OQS07224.1 - 0.033 15.0 1.7 0.27 12.1 1.4 2.6 2 1 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Peptidase_S9_N PF02897.15 OQS07225.1 - 7.3e-109 364.3 0.3 9.8e-109 363.9 0.3 1.1 1 0 0 1 1 1 1 Prolyl oligopeptidase, N-terminal beta-propeller domain Peptidase_S9 PF00326.21 OQS07225.1 - 1.4e-63 214.2 0.0 2.1e-63 213.6 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_3 PF07859.13 OQS07225.1 - 0.0099 15.8 0.0 0.025 14.4 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 OQS07225.1 - 0.035 13.4 0.1 0.064 12.5 0.1 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 BAAT_C PF08840.11 OQS07225.1 - 0.051 13.5 0.0 0.15 11.9 0.0 1.8 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal RRM_5 PF13893.6 OQS07226.1 - 1.5e-42 144.2 0.3 5e-24 84.3 0.0 4.1 2 2 2 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.22 OQS07226.1 - 2.7e-32 110.4 0.7 3.4e-08 33.2 0.0 4.2 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_8 PF11835.8 OQS07226.1 - 5.3e-13 49.0 0.2 5.9e-10 39.2 0.1 3.5 4 0 0 4 4 4 1 RRM-like domain RRM_occluded PF16842.5 OQS07226.1 - 5.3e-09 35.8 0.1 8.9e-05 22.3 0.0 4.2 4 0 0 4 4 4 2 Occluded RNA-recognition motif RL PF17797.1 OQS07226.1 - 2.6e-05 24.1 0.1 1.2 9.1 0.0 3.7 4 0 0 4 4 4 2 RL domain TMEM154 PF15102.6 OQS07227.1 - 0.0062 16.4 12.4 0.054 13.4 11.0 2.5 2 1 0 2 2 2 1 TMEM154 protein family DUF5305 PF17231.2 OQS07227.1 - 0.089 12.2 0.8 0.14 11.6 0.8 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5305) Syndecan PF01034.20 OQS07227.1 - 0.13 12.2 0.1 0.24 11.4 0.1 1.3 1 0 0 1 1 1 0 Syndecan domain DUF5427 PF10310.9 OQS07227.1 - 0.82 8.6 3.3 1.1 8.1 3.3 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5427) DUF919 PF06034.11 OQS07228.1 - 0.24 11.3 4.9 0.68 9.8 4.9 1.8 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF919) ABC_membrane PF00664.23 OQS07230.1 - 1.3e-46 159.5 31.3 8.7e-29 101.0 13.9 2.3 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 OQS07230.1 - 1.6e-19 70.8 0.0 3e-19 69.9 0.0 1.5 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 OQS07230.1 - 2.3e-05 24.0 1.3 0.035 13.6 0.7 2.3 1 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 OQS07230.1 - 0.0026 17.6 0.2 0.007 16.2 0.1 1.7 1 1 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 OQS07230.1 - 0.0029 17.3 0.2 0.0061 16.3 0.2 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 OQS07230.1 - 0.019 14.9 0.1 0.038 13.9 0.1 1.4 1 0 0 1 1 1 0 RsgA GTPase Dynamin_N PF00350.23 OQS07230.1 - 0.046 13.8 0.0 0.098 12.7 0.0 1.5 1 0 0 1 1 1 0 Dynamin family MMR_HSR1 PF01926.23 OQS07230.1 - 0.063 13.4 0.1 0.2 11.8 0.0 1.8 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_23 PF13476.6 OQS07230.1 - 0.071 13.6 0.1 0.12 12.9 0.1 1.3 1 0 0 1 1 1 0 AAA domain AAA_15 PF13175.6 OQS07230.1 - 0.097 12.4 0.1 0.14 11.8 0.1 1.2 1 0 0 1 1 1 0 AAA ATPase domain AAA_16 PF13191.6 OQS07230.1 - 0.12 12.7 0.0 0.24 11.7 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain HEAT PF02985.22 OQS07232.1 - 1.8e-31 105.5 34.2 0.001 19.1 0.1 13.9 14 0 0 14 14 14 9 HEAT repeat HEAT_2 PF13646.6 OQS07232.1 - 2.6e-25 88.6 16.5 1.7e-06 28.3 0.0 7.1 4 3 2 6 6 6 4 HEAT repeats Vac14_Fab1_bd PF12755.7 OQS07232.1 - 2.9e-10 40.6 0.1 0.95 10.1 0.0 6.6 4 3 2 6 6 6 2 Vacuolar 14 Fab1-binding region zf-RING_2 PF13639.6 OQS07232.1 - 3.5e-10 40.1 6.9 3.5e-10 40.1 6.9 2.7 3 0 0 3 3 1 1 Ring finger domain HEAT_EZ PF13513.6 OQS07232.1 - 1e-09 38.6 18.5 0.0026 18.2 0.3 8.6 7 2 3 10 10 8 4 HEAT-like repeat zf-C3HC4_2 PF13923.6 OQS07232.1 - 1.2e-09 37.8 7.2 1.2e-09 37.8 7.2 2.8 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 OQS07232.1 - 8.6e-08 31.8 2.1 2.5e-07 30.3 2.1 1.9 1 0 0 1 1 1 1 RING-like zinc finger zf-rbx1 PF12678.7 OQS07232.1 - 4.7e-06 26.8 8.9 1.8e-05 24.9 8.9 2.0 1 1 0 1 1 1 1 RING-H2 zinc finger domain Cnd1 PF12717.7 OQS07232.1 - 5.4e-06 26.5 4.5 0.00016 21.8 0.1 4.0 3 1 1 4 4 4 1 non-SMC mitotic condensation complex subunit 1 zinc_ribbon_9 PF14369.6 OQS07232.1 - 1.3e-05 25.3 8.7 1.3e-05 25.3 8.7 2.2 2 0 0 2 2 1 1 zinc-ribbon Adaptin_N PF01602.20 OQS07232.1 - 2.7e-05 23.0 10.0 0.23 10.0 0.7 4.4 3 1 0 4 4 4 2 Adaptin N terminal region zf-C3HC4 PF00097.25 OQS07232.1 - 3.8e-05 23.5 5.4 3.8e-05 23.5 5.4 2.8 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) CLASP_N PF12348.8 OQS07232.1 - 0.00042 19.9 0.3 0.35 10.4 0.0 3.3 2 2 0 3 3 3 1 CLASP N terminal zf-ANAPC11 PF12861.7 OQS07232.1 - 0.0029 17.6 3.3 0.019 15.0 3.2 2.5 2 1 0 2 2 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.6 OQS07232.1 - 0.0045 16.9 3.4 0.0045 16.9 3.4 2.9 3 0 0 3 3 3 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 OQS07232.1 - 0.008 16.0 4.1 0.008 16.0 4.1 2.6 3 0 0 3 3 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OQS07232.1 - 0.012 15.6 5.3 0.057 13.5 5.3 2.3 1 0 0 1 1 1 0 RING-type zinc-finger Ecm29 PF13001.7 OQS07232.1 - 0.019 13.6 1.3 1.5 7.4 0.2 3.1 3 1 1 4 4 4 0 Proteasome stabiliser Dopey_N PF04118.14 OQS07232.1 - 0.078 12.1 0.1 0.16 11.0 0.1 1.4 1 0 0 1 1 1 0 Dopey, N-terminal Prok-RING_4 PF14447.6 OQS07232.1 - 0.14 12.1 10.1 0.022 14.6 4.8 2.5 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 zf-C2H2_2 PF12756.7 OQS07232.1 - 0.15 12.4 0.9 3.4 8.1 0.0 2.9 3 0 0 3 3 2 0 C2H2 type zinc-finger (2 copies) Arm PF00514.23 OQS07232.1 - 0.77 9.9 7.3 23 5.2 0.1 5.2 5 0 0 5 5 4 0 Armadillo/beta-catenin-like repeat Vps39_2 PF10367.9 OQS07232.1 - 4.3 7.8 6.8 17 5.9 0.5 3.8 4 0 0 4 4 3 0 Vacuolar sorting protein 39 domain 2 GTP_EFTU PF00009.27 OQS07233.1 - 5.4e-30 104.4 1.9 3.6e-28 98.4 1.9 2.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.8 OQS07233.1 - 8e-12 45.2 0.1 1.2e-10 41.4 0.0 2.5 2 0 0 2 2 2 1 Translation-initiation factor 2 MMR_HSR1 PF01926.23 OQS07233.1 - 5.2e-10 39.4 0.0 1.7e-09 37.8 0.0 1.9 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 OQS07233.1 - 1e-08 34.9 0.5 4.2e-08 32.9 0.4 2.1 2 1 0 2 2 2 1 Ferrous iron transport protein B PduV-EutP PF10662.9 OQS07233.1 - 1.1e-08 35.0 0.1 2.5e-08 33.8 0.1 1.6 1 0 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation MMR_HSR1_Xtn PF16897.5 OQS07233.1 - 4.2e-07 29.9 1.2 1.2e-06 28.4 0.1 2.3 2 0 0 2 2 2 1 C-terminal region of MMR_HSR1 domain RsgA_GTPase PF03193.16 OQS07233.1 - 1e-06 28.8 0.9 0.00052 20.0 0.2 2.5 1 1 1 2 2 2 2 RsgA GTPase IF2_N PF04760.15 OQS07233.1 - 7.8e-05 22.4 0.0 0.00038 20.2 0.0 2.2 2 0 0 2 2 2 1 Translation initiation factor IF-2, N-terminal region Ras PF00071.22 OQS07233.1 - 0.018 14.6 0.9 0.054 13.1 0.0 2.2 3 0 0 3 3 3 0 Ras family cobW PF02492.19 OQS07233.1 - 0.058 13.0 0.9 3.2 7.3 0.1 2.3 1 1 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Dynamin_N PF00350.23 OQS07233.1 - 0.065 13.3 0.0 0.44 10.6 0.0 2.2 1 1 1 2 2 2 0 Dynamin family Phtf-FEM1B_bdg PF12129.8 OQS07234.1 - 3.8e-18 65.8 0.2 1.4e-17 63.9 0.0 2.0 2 0 0 2 2 2 1 Male germ-cell putative homeodomain transcription factor DUF679 PF05078.12 OQS07234.1 - 0.02 14.9 1.3 0.055 13.4 1.3 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF679) Beach PF02138.18 OQS07236.1 - 7.1e-84 281.4 0.0 1.3e-83 280.6 0.0 1.4 1 0 0 1 1 1 1 Beige/BEACH domain ELMO_CED12 PF04727.13 OQS07236.1 - 1.5e-27 96.8 0.1 5.2e-27 95.1 0.1 2.0 1 0 0 1 1 1 1 ELMO/CED-12 family PIH1 PF08190.12 OQS07236.1 - 2e-17 63.1 0.0 4.2e-17 62.1 0.0 1.5 1 0 0 1 1 1 1 PIH1 N-terminal domain DUF4704 PF15787.5 OQS07236.1 - 1.8e-14 53.7 3.8 1.8e-14 53.7 3.8 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4704) Laminin_G_3 PF13385.6 OQS07236.1 - 7.1e-09 36.0 0.0 2e-08 34.5 0.0 1.8 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily PH_BEACH PF14844.6 OQS07236.1 - 2.8e-08 33.8 0.0 9.8e-08 32.0 0.0 2.0 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH YqcI_YcgG PF08892.11 OQS07236.1 - 0.087 12.6 0.3 8.7 6.1 0.0 2.4 2 0 0 2 2 2 0 YqcI/YcgG family SPA PF08616.10 OQS07237.1 - 1.3e-28 99.2 0.0 2.4e-28 98.3 0.0 1.4 1 0 0 1 1 1 1 Stabilization of polarity axis DUF2347 PF09804.9 OQS07237.1 - 1.8e-16 60.6 0.0 4e-16 59.4 0.0 1.6 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2347) Afi1 PF07792.12 OQS07237.1 - 1.4e-13 51.5 0.0 6e-13 49.4 0.0 2.0 1 1 0 1 1 1 1 Docking domain of Afi1 for Arf3 in vesicle trafficking Avl9 PF09794.9 OQS07237.1 - 1e-11 44.2 0.8 7.2e-06 24.9 0.1 2.9 1 1 1 2 2 2 2 Transport protein Avl9 DNA_pol3_gamma3 PF12169.8 OQS07238.1 - 0.011 15.6 0.3 0.024 14.6 0.3 1.6 1 0 0 1 1 1 0 DNA polymerase III subunits gamma and tau domain III C9orf72-like PF15019.6 OQS07238.1 - 0.021 14.4 0.1 0.04 13.5 0.1 1.4 1 0 0 1 1 1 0 C9orf72-like protein family Shigella_OspC PF06128.11 OQS07238.1 - 0.06 13.1 0.5 1.3 8.6 0.0 2.0 1 1 1 2 2 2 0 Shigella flexneri OspC protein DAGK_cat PF00781.24 OQS07239.1 - 5.6e-29 100.3 0.0 9.3e-29 99.6 0.0 1.4 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain LRR_6 PF13516.6 OQS07240.1 - 0.076 13.1 10.4 0.084 13.0 0.2 4.0 4 0 0 4 4 4 0 Leucine Rich repeat LRR_4 PF12799.7 OQS07240.1 - 0.16 12.4 5.5 2.3 8.8 1.1 3.1 2 1 1 3 3 3 0 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 OQS07240.1 - 0.23 11.3 4.2 5.3 6.9 1.1 2.6 1 1 1 2 2 2 0 Leucine rich repeat GPCR_chapero_1 PF11904.8 OQS07241.1 - 4.8e-43 147.8 0.0 8.9e-43 146.9 0.0 1.4 1 1 0 1 1 1 1 GPCR-chaperone Ank_2 PF12796.7 OQS07241.1 - 1.7e-08 34.9 0.0 4e-08 33.7 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQS07241.1 - 5.8e-06 26.8 0.3 0.00088 19.8 0.3 3.2 1 1 0 2 2 2 1 Ankyrin repeats (many copies) GOLD_2 PF13897.6 OQS07241.1 - 4.2e-05 24.1 1.0 0.04 14.4 0.0 2.3 1 1 1 2 2 2 2 Golgi-dynamics membrane-trafficking Ank_3 PF13606.6 OQS07241.1 - 0.0034 17.7 0.1 6.5 7.7 0.0 3.6 3 0 0 3 3 3 1 Ankyrin repeat Ank PF00023.30 OQS07241.1 - 0.007 16.8 0.1 18 6.0 0.0 3.4 3 0 0 3 3 3 1 Ankyrin repeat Ank_5 PF13857.6 OQS07241.1 - 0.017 15.4 0.3 16 5.9 0.0 3.2 2 1 1 3 3 3 0 Ankyrin repeats (many copies) DUF1843 PF08898.10 OQS07241.1 - 0.098 13.2 1.0 3.9 8.1 0.0 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF1843) IBR PF01485.21 OQS07242.1 - 6.6e-05 23.1 4.9 0.00012 22.2 4.9 1.4 1 0 0 1 1 1 1 IBR domain, a half RING-finger domain OrfB_Zn_ribbon PF07282.11 OQS07242.1 - 0.049 13.5 3.9 0.092 12.7 3.9 1.4 1 0 0 1 1 1 0 Putative transposase DNA-binding domain Barttin PF15462.6 OQS07242.1 - 0.064 13.0 0.2 0.079 12.7 0.2 1.1 1 0 0 1 1 1 0 Bartter syndrome, infantile, with sensorineural deafness (Barttin) DZR PF12773.7 OQS07242.1 - 0.1 12.7 6.8 0.2 11.7 5.2 2.2 1 1 1 2 2 2 0 Double zinc ribbon Prok-RING_1 PF14446.6 OQS07242.1 - 0.11 12.5 6.6 0.23 11.4 6.6 1.5 1 1 0 1 1 1 0 Prokaryotic RING finger family 1 zinc-ribbons_6 PF07191.12 OQS07242.1 - 0.43 10.6 6.5 2 8.5 6.5 2.0 1 1 0 1 1 1 0 zinc-ribbons RNA_POL_M_15KD PF02150.16 OQS07242.1 - 0.53 10.2 7.1 0.93 9.4 0.1 3.4 1 1 2 3 3 3 0 RNA polymerases M/15 Kd subunit DNA_RNApol_7kD PF03604.13 OQS07242.1 - 0.58 9.9 5.7 0.76 9.5 3.5 2.1 2 0 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit zinc_ribbon_4 PF13717.6 OQS07242.1 - 0.61 10.0 8.7 0.35 10.8 0.5 3.0 3 0 0 3 3 3 0 zinc-ribbon domain Zn-ribbon_8 PF09723.10 OQS07242.1 - 0.81 9.9 8.2 19 5.5 7.8 2.6 1 1 1 2 2 2 0 Zinc ribbon domain HypA PF01155.19 OQS07242.1 - 1.9 8.6 6.9 8.8 6.4 6.6 1.9 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA C1_4 PF07975.12 OQS07242.1 - 2.2 8.6 7.6 1.3 9.3 5.2 1.9 2 1 0 2 2 2 0 TFIIH C1-like domain Nudix_N_2 PF14803.6 OQS07242.1 - 4.6 7.2 10.7 1 9.4 5.0 2.5 2 0 0 2 2 2 0 Nudix N-terminal AAA_13 PF13166.6 OQS07243.1 - 0.00096 17.9 29.6 0.00096 17.9 29.6 8.1 1 1 5 8 8 8 4 AAA domain ATG16 PF08614.11 OQS07243.1 - 0.013 15.7 5.1 0.013 15.7 5.1 12.1 2 1 9 11 11 11 0 Autophagy protein 16 (ATG16) YabA PF06156.13 OQS07243.1 - 0.02 15.5 1.8 0.02 15.5 1.8 17.1 3 2 12 16 16 16 0 Initiation control protein YabA DehI PF10778.9 OQS07243.1 - 6.5 6.9 11.4 0.22 11.6 1.9 3.6 3 0 0 3 3 3 0 Halocarboxylic acid dehydrogenase DehI HABP4_PAI-RBP1 PF04774.15 OQS07244.1 - 8.5e-05 23.4 1.1 9.4e-05 23.2 1.1 1.2 1 0 0 1 1 1 1 Hyaluronan / mRNA binding family GCV_T PF01571.21 OQS07245.1 - 6.4e-66 222.3 0.0 8.7e-66 221.9 0.0 1.2 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain DAO PF01266.24 OQS07245.1 - 6.6e-61 206.8 0.1 9.2e-61 206.4 0.1 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase GCV_T_C PF08669.11 OQS07245.1 - 1.7e-17 63.1 0.0 4.2e-17 61.8 0.0 1.7 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain FAO_M PF16350.5 OQS07245.1 - 2.1e-11 43.9 0.1 4.8e-11 42.8 0.1 1.7 1 0 0 1 1 1 1 FAD dependent oxidoreductase central domain FAD_binding_3 PF01494.19 OQS07245.1 - 4.1e-06 26.3 0.1 0.0071 15.6 0.4 2.2 2 0 0 2 2 2 2 FAD binding domain FAD_binding_2 PF00890.24 OQS07245.1 - 9.1e-06 25.0 0.0 2.1e-05 23.8 0.0 1.6 1 0 0 1 1 1 1 FAD binding domain SoxG PF04268.12 OQS07245.1 - 2.2e-05 24.7 0.0 4.9e-05 23.5 0.0 1.6 1 0 0 1 1 1 1 Sarcosine oxidase, gamma subunit family Pyr_redox_2 PF07992.14 OQS07245.1 - 0.00018 20.8 0.0 0.00043 19.6 0.0 1.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 OQS07245.1 - 0.00027 20.2 0.3 0.00053 19.3 0.3 1.4 1 0 0 1 1 1 1 Thi4 family NAD_binding_8 PF13450.6 OQS07245.1 - 0.0007 19.8 0.8 0.0037 17.4 0.3 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 OQS07245.1 - 0.00078 18.8 0.1 0.058 12.6 0.3 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.16 OQS07245.1 - 0.0089 15.7 0.2 0.019 14.6 0.2 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Pyr_redox PF00070.27 OQS07245.1 - 0.0097 16.4 0.4 0.033 14.7 0.4 1.9 2 0 0 2 2 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.6 OQS07245.1 - 0.013 15.9 0.0 0.03 14.7 0.0 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding FAD_oxidored PF12831.7 OQS07245.1 - 0.017 14.5 0.1 0.028 13.8 0.1 1.5 1 1 0 1 1 1 0 FAD dependent oxidoreductase GIDA PF01134.22 OQS07245.1 - 0.02 14.0 0.9 0.03 13.4 0.9 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Lycopene_cycl PF05834.12 OQS07245.1 - 0.064 12.3 0.3 0.097 11.7 0.3 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein Shikimate_DH PF01488.20 OQS07245.1 - 0.076 13.1 0.0 0.19 11.8 0.0 1.6 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase AlaDh_PNT_C PF01262.21 OQS07245.1 - 0.089 12.1 0.2 0.16 11.2 0.2 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.18 OQS07245.1 - 0.1 12.5 0.4 0.18 11.7 0.4 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_9 PF13454.6 OQS07245.1 - 0.12 12.3 1.3 1.1 9.3 0.2 2.7 3 0 0 3 3 3 0 FAD-NAD(P)-binding TrkA_N PF02254.18 OQS07245.1 - 0.19 12.0 0.1 0.41 10.9 0.1 1.6 1 0 0 1 1 1 0 TrkA-N domain Leu_zip PF15294.6 OQS07246.1 - 0.0052 16.3 14.0 0.0052 16.3 14.0 2.1 1 1 1 2 2 2 1 Leucine zipper betaPIX_CC PF16523.5 OQS07246.1 - 0.019 14.8 6.4 0.059 13.2 6.4 1.9 1 0 0 1 1 1 0 betaPIX coiled coil HrpB7 PF09486.10 OQS07246.1 - 0.021 15.2 7.4 0.021 15.2 7.4 2.0 2 0 0 2 2 2 0 Bacterial type III secretion protein (HrpB7) Bcr-Abl_Oligo PF09036.10 OQS07246.1 - 0.031 14.3 2.0 0.095 12.7 2.0 1.8 1 0 0 1 1 1 0 Bcr-Abl oncoprotein oligomerisation domain LMBR1 PF04791.16 OQS07246.1 - 0.52 9.2 3.8 0.8 8.5 3.8 1.4 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF1759 PF03564.15 OQS07246.1 - 4.2 7.3 9.2 0.087 12.8 1.1 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1759) Med7 PF05983.11 OQS07248.1 - 3e-41 141.6 0.3 3e-41 141.6 0.3 2.9 1 1 2 3 3 3 2 MED7 protein CNDH2_C PF16858.5 OQS07248.1 - 0.015 15.2 2.5 0.018 14.9 2.5 1.1 1 0 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term Atg14 PF10186.9 OQS07248.1 - 0.081 12.0 1.2 0.1 11.7 1.2 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 SpoIIE PF07228.12 OQS07249.1 - 6.3e-10 39.3 0.0 1.3e-09 38.3 0.0 1.5 2 0 0 2 2 2 1 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.6 OQS07249.1 - 7.1e-07 29.1 0.0 1.5e-06 28.0 0.0 1.5 1 0 0 1 1 1 1 Protein phosphatase 2C SSFA2_C PF14723.6 OQS07249.1 - 0.074 13.0 0.0 2.3 8.1 0.0 2.2 1 1 1 2 2 2 0 Sperm-specific antigen 2 C-terminus Mannosyl_trans3 PF11051.8 OQS07250.1 - 1.5e-24 86.8 0.0 2.2e-24 86.3 0.0 1.2 1 0 0 1 1 1 1 Mannosyltransferase putative CRM1_C PF08767.11 OQS07251.1 - 3.7e-109 364.8 6.4 9.6e-108 360.1 2.8 3.4 2 1 0 2 2 2 1 CRM1 C terminal Xpo1 PF08389.12 OQS07251.1 - 2.5e-34 118.5 5.9 2.5e-34 118.5 5.9 3.5 4 0 0 4 4 4 1 Exportin 1-like protein CRM1_repeat_2 PF18784.1 OQS07251.1 - 1.1e-30 105.0 1.9 1.1e-30 105.0 1.9 2.0 2 0 0 2 2 2 1 CRM1 / Exportin repeat 2 CRM1_repeat_3 PF18787.1 OQS07251.1 - 1.9e-29 101.5 1.3 1.9e-29 101.5 1.3 2.1 2 0 0 2 2 2 1 CRM1 / Exportin repeat 3 CRM1_repeat PF18777.1 OQS07251.1 - 7.6e-18 63.7 0.4 2e-17 62.4 0.4 1.8 1 0 0 1 1 1 1 Chromosome region maintenance or exportin repeat IBN_N PF03810.19 OQS07251.1 - 7.1e-12 45.1 0.0 3.1e-11 43.0 0.0 2.3 1 0 0 1 1 1 1 Importin-beta N-terminal domain BID PF06393.11 OQS07251.1 - 0.0042 16.7 0.1 0.035 13.7 0.1 2.5 3 0 0 3 3 3 1 BH3 interacting domain (BID) Lipase_GDSL PF00657.22 OQS07252.1 - 0.0014 18.7 0.1 0.0051 16.8 0.1 1.9 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase HD PF01966.22 OQS07253.1 - 0.058 13.6 0.2 0.33 11.2 0.0 2.5 3 1 0 3 3 3 0 HD domain APH PF01636.23 OQS07254.1 - 4.9e-14 52.8 0.0 1.2e-13 51.6 0.0 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.20 OQS07254.1 - 0.00098 18.5 0.0 0.0029 17.0 0.0 1.8 2 0 0 2 2 2 1 Ecdysteroid kinase DUF1679 PF07914.11 OQS07254.1 - 0.0034 16.3 0.0 0.0056 15.6 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1679) Choline_kinase PF01633.20 OQS07254.1 - 0.004 16.8 0.0 0.0069 16.0 0.0 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase MecA PF05389.12 OQS07254.1 - 0.029 14.0 0.1 0.051 13.2 0.1 1.3 1 0 0 1 1 1 0 Negative regulator of genetic competence (MecA) Type_III_YscG PF09477.10 OQS07254.1 - 0.083 13.0 0.1 0.18 11.9 0.1 1.6 1 0 0 1 1 1 0 Bacterial type II secretion system chaperone protein (type_III_yscG) Pkinase PF00069.25 OQS07254.1 - 0.091 12.1 0.0 14 5.0 0.0 2.4 2 1 0 2 2 2 0 Protein kinase domain PPR PF01535.20 OQS07254.1 - 0.6 10.5 2.5 2.6 8.5 0.3 2.5 2 0 0 2 2 2 0 PPR repeat WD40 PF00400.32 OQS07255.1 - 2.5e-06 28.1 8.1 2.3 9.2 0.1 5.8 6 0 0 6 6 6 3 WD domain, G-beta repeat Hira PF07569.11 OQS07255.1 - 0.0051 16.6 0.1 6.8 6.4 0.0 3.3 2 1 1 3 3 3 2 TUP1-like enhancer of split ANAPC4_WD40 PF12894.7 OQS07255.1 - 0.077 13.3 0.0 2.4 8.5 0.0 3.2 3 1 1 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain Ion_trans PF00520.31 OQS07256.1 - 1.9e-31 109.1 49.7 1.4e-19 70.3 19.9 2.1 2 0 0 2 2 2 2 Ion transport protein EF-hand_8 PF13833.6 OQS07256.1 - 0.083 12.7 0.0 0.24 11.3 0.0 1.8 1 0 0 1 1 1 0 EF-hand domain pair PDR_CDR PF06422.12 OQS07256.1 - 0.8 9.7 7.9 8.9 6.3 0.3 3.7 3 0 0 3 3 3 0 CDR ABC transporter GATase PF00117.28 OQS07257.1 - 1e-15 58.0 0.0 1.4e-15 57.6 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 OQS07257.1 - 0.00043 20.1 0.0 0.00073 19.3 0.0 1.4 1 0 0 1 1 1 1 Peptidase C26 Histone PF00125.24 OQS07258.1 - 5.4e-20 72.1 0.2 6.6e-20 71.8 0.2 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID_20kDa PF03847.13 OQS07258.1 - 0.00022 21.6 0.0 0.00036 21.0 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A CBFD_NFYB_HMF PF00808.23 OQS07258.1 - 0.0015 18.7 0.0 0.0034 17.6 0.0 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone YscO-like PF16789.5 OQS07258.1 - 0.0039 17.2 0.1 0.0045 17.0 0.1 1.1 1 0 0 1 1 1 1 YscO-like protein adh_short_C2 PF13561.6 OQS07259.1 - 1.2e-66 224.7 3.8 1.4e-66 224.4 3.8 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OQS07259.1 - 2.2e-49 167.6 2.7 2.7e-49 167.3 2.7 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OQS07259.1 - 6.7e-12 45.7 2.1 1.2e-11 44.8 2.1 1.4 1 1 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 OQS07259.1 - 0.0086 15.2 0.2 0.013 14.6 0.2 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.19 OQS07259.1 - 0.014 14.4 0.5 0.048 12.7 0.3 1.8 2 0 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family Histone_H2A_C PF16211.5 OQS07260.1 - 4.8e-20 71.0 2.2 8.8e-20 70.2 2.2 1.5 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 OQS07260.1 - 4.2e-16 59.5 0.0 5.2e-16 59.2 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 OQS07260.1 - 0.00033 20.9 0.0 0.00043 20.5 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Kelch_5 PF13854.6 OQS07261.1 - 9.5e-31 105.3 11.9 4.5e-07 29.7 0.0 6.6 7 0 0 7 7 7 6 Kelch motif Kelch_3 PF13415.6 OQS07261.1 - 9e-28 96.0 2.1 3e-10 40.1 0.0 7.2 7 0 0 7 7 7 4 Galactose oxidase, central domain Kelch_4 PF13418.6 OQS07261.1 - 8.3e-23 80.1 16.5 4.4e-05 23.4 0.1 7.1 5 2 2 7 7 7 6 Galactose oxidase, central domain Kelch_6 PF13964.6 OQS07261.1 - 2.7e-20 71.9 7.3 6.9e-05 23.0 0.1 6.9 4 3 2 6 6 6 5 Kelch motif Kelch_1 PF01344.25 OQS07261.1 - 3.2e-18 65.0 5.6 0.00011 21.8 0.0 7.0 7 1 0 7 7 7 4 Kelch motif Kelch_2 PF07646.15 OQS07261.1 - 7e-10 38.5 11.2 0.051 13.6 0.0 5.9 6 1 0 6 6 6 3 Kelch motif RAG2 PF03089.14 OQS07261.1 - 4e-05 22.8 0.0 1.9 7.4 0.0 3.9 2 1 2 4 4 4 3 Recombination activating protein 2 CENP-K PF11802.8 OQS07262.1 - 0.0023 17.6 0.1 0.43 10.1 0.0 2.0 1 1 1 2 2 2 2 Centromere-associated protein K Drf_FH3 PF06367.16 OQS07262.1 - 0.019 14.6 0.1 0.021 14.4 0.1 1.2 1 0 0 1 1 1 0 Diaphanous FH3 Domain Med29 PF11568.8 OQS07262.1 - 0.037 14.3 0.1 0.045 14.0 0.1 1.2 1 0 0 1 1 1 0 Mediator complex subunit 29 Aa_trans PF01490.18 OQS07263.1 - 2.4e-82 276.9 94.3 4.9e-39 134.2 40.2 4.1 4 0 0 4 4 4 4 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 OQS07263.1 - 1.9e-13 50.3 65.9 2.4e-11 43.3 22.2 3.9 4 0 0 4 4 4 3 Tryptophan/tyrosine permease family GST_C_3 PF14497.6 OQS07264.1 - 1.1e-09 38.3 0.0 1.4e-09 38.1 0.0 1.0 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 OQS07264.1 - 0.00029 20.8 0.0 0.00074 19.5 0.0 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 OQS07264.1 - 0.0027 17.9 0.0 0.0032 17.7 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Trypsin_2 PF13365.6 OQS07265.1 - 2e-06 28.8 0.0 3.4e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 Trypsin-like peptidase domain IQ PF00612.27 OQS07265.1 - 0.00048 19.7 8.7 0.14 12.1 2.7 3.2 2 0 0 2 2 2 2 IQ calmodulin-binding motif Elicitin PF00964.17 OQS07265.1 - 0.0039 17.2 1.5 0.012 15.7 1.5 1.9 1 0 0 1 1 1 1 Elicitin fn3 PF00041.21 OQS07265.1 - 0.062 13.7 0.0 0.16 12.3 0.0 1.8 1 0 0 1 1 1 0 Fibronectin type III domain EHN PF06441.12 OQS07265.1 - 0.17 12.3 0.5 0.74 10.2 0.1 2.3 2 0 0 2 2 2 0 Epoxide hydrolase N terminus WW PF00397.26 OQS07265.1 - 0.73 10.0 2.7 2.3 8.4 2.7 1.9 1 0 0 1 1 1 0 WW domain Mer2 PF09074.10 OQS07265.1 - 4.7 7.0 8.3 0.58 9.9 1.1 2.6 3 0 0 3 3 3 0 Mer2 Elicitin PF00964.17 OQS07267.1 - 8.5e-08 32.2 3.9 0.00015 21.8 0.6 2.4 2 0 0 2 2 2 2 Elicitin DUF202 PF02656.15 OQS07267.1 - 0.0089 16.5 0.1 0.018 15.5 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF202) Saf_2TM PF18303.1 OQS07267.1 - 0.018 14.6 0.0 0.032 13.8 0.0 1.3 1 0 0 1 1 1 0 SAVED-fused 2TM effector domain DUF4328 PF14219.6 OQS07267.1 - 0.026 14.1 0.1 0.042 13.4 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4328) TMEM100 PF16311.5 OQS07267.1 - 0.052 13.1 1.7 0.056 13.0 0.1 1.9 2 1 0 2 2 2 0 Transmembrane protein 100 DUF5305 PF17231.2 OQS07267.1 - 0.066 12.6 0.6 0.12 11.8 0.0 1.6 2 0 0 2 2 2 0 Family of unknown function (DUF5305) GspL_C PF12693.7 OQS07267.1 - 0.096 12.5 0.2 0.18 11.7 0.2 1.4 1 0 0 1 1 1 0 GspL periplasmic domain CD99L2 PF12301.8 OQS07267.1 - 0.12 12.7 1.1 0.98 9.7 0.1 2.2 2 0 0 2 2 2 0 CD99 antigen like protein 2 Orf78 PF06024.12 OQS07267.1 - 0.13 12.6 0.4 0.98 9.8 0.0 2.1 2 0 0 2 2 2 0 Orf78 (ac78) Insulin_TMD PF17870.1 OQS07267.1 - 0.14 12.2 0.3 0.31 11.1 0.3 1.5 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment Phage_Coat_B PF05356.11 OQS07267.1 - 0.56 10.1 3.6 0.27 11.2 0.2 2.1 2 0 0 2 2 2 0 Phage Coat protein B SBF PF01758.16 OQS07268.1 - 6.2e-36 123.9 18.3 6.2e-36 123.9 18.3 2.5 3 0 0 3 3 3 1 Sodium Bile acid symporter family SBF_like PF13593.6 OQS07268.1 - 9.9e-07 28.4 28.1 1.3e-06 28.0 28.1 1.1 1 0 0 1 1 1 1 SBF-like CPA transporter family (DUF4137) Histone PF00125.24 OQS07269.1 - 8.8e-54 181.4 1.2 9.8e-54 181.2 1.2 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 PAF PF15715.5 OQS07269.1 - 0.00038 21.0 2.1 0.00048 20.7 2.1 1.1 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CENP-T_C PF15511.6 OQS07269.1 - 0.0009 19.3 0.3 0.0015 18.6 0.0 1.5 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 OQS07269.1 - 0.00091 19.6 0.0 0.0014 19.0 0.0 1.2 1 0 0 1 1 1 1 CENP-S protein CBFD_NFYB_HMF PF00808.23 OQS07269.1 - 0.023 14.9 0.0 0.046 14.0 0.0 1.5 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 OQS07269.1 - 0.033 14.3 0.1 0.059 13.4 0.0 1.5 2 0 0 2 2 2 0 Transcription initiation factor IID, 31kD subunit CENP-T_C PF15511.6 OQS07270.1 - 1.1e-08 35.1 0.1 1.4e-08 34.8 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 OQS07270.1 - 9.1e-05 22.8 0.1 0.00012 22.4 0.1 1.3 1 1 0 1 1 1 1 CENP-S protein TAF PF02969.17 OQS07270.1 - 0.00045 20.3 0.1 0.00063 19.9 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.23 OQS07270.1 - 0.0022 18.2 0.1 0.0036 17.6 0.1 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 OQS07270.1 - 0.0025 18.2 0.2 0.0028 18.0 0.2 1.3 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-31kDa PF02291.15 OQS07270.1 - 0.017 15.2 0.0 0.019 15.0 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 OQS07270.1 - 0.067 13.2 0.0 0.1 12.6 0.0 1.2 1 0 0 1 1 1 0 Bromodomain associated Myotub-related PF06602.14 OQS07272.1 - 1.2e-122 409.2 0.0 3e-122 407.9 0.0 1.6 2 0 0 2 2 2 1 Myotubularin-like phosphatase domain RabGAP-TBC PF00566.18 OQS07272.1 - 1.5e-28 99.9 2.5 8.2e-14 51.8 0.1 2.4 2 0 0 2 2 2 2 Rab-GTPase-TBC domain GRAM PF02893.20 OQS07272.1 - 0.00037 20.4 0.2 0.00084 19.2 0.2 1.5 1 0 0 1 1 1 1 GRAM domain PDZ_6 PF17820.1 OQS07272.1 - 0.0078 16.0 0.0 0.024 14.5 0.0 1.8 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 OQS07272.1 - 0.0085 16.4 0.0 0.018 15.4 0.0 1.5 1 0 0 1 1 1 1 PDZ domain Myb_DNA-bind_7 PF15963.5 OQS07273.1 - 1.2e-06 28.3 1.2 0.0074 16.2 0.1 2.8 2 0 0 2 2 2 2 Myb DNA-binding like Myb_DNA-binding PF00249.31 OQS07273.1 - 8.5e-05 22.7 0.0 0.65 10.2 0.0 2.8 2 0 0 2 2 2 2 Myb-like DNA-binding domain GCFC PF07842.12 OQS07274.1 - 3.5e-47 161.3 7.5 5.4e-47 160.7 7.5 1.3 1 0 0 1 1 1 1 GC-rich sequence DNA-binding factor-like protein G-patch PF01585.23 OQS07274.1 - 3.2e-12 46.1 1.0 9.2e-12 44.7 1.0 1.9 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 OQS07274.1 - 9.8e-06 25.6 2.0 3.3e-05 23.9 2.0 1.9 1 0 0 1 1 1 1 G-patch domain Baculo_PEP_C PF04513.12 OQS07275.1 - 0.061 13.4 0.5 0.21 11.6 0.1 2.1 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus GARP PF16731.5 OQS07275.1 - 0.18 11.4 1.4 0.72 9.5 0.4 2.3 2 0 0 2 2 2 0 Glutamic acid/alanine-rich protein of Trypanosoma ApoL PF05461.11 OQS07275.1 - 1.2 8.4 7.7 2.3 7.4 3.6 2.2 2 0 0 2 2 2 0 Apolipoprotein L IRK PF01007.20 OQS07276.1 - 6.8e-11 42.2 13.8 1.7e-08 34.4 0.9 2.5 2 1 1 3 3 3 2 Inward rectifier potassium channel transmembrane domain IRK_C PF17655.1 OQS07276.1 - 0.0018 17.9 0.2 0.0026 17.4 0.2 1.2 1 0 0 1 1 1 1 Inward rectifier potassium channel C-terminal domain Ion_trans_2 PF07885.16 OQS07276.1 - 0.47 10.4 14.1 0.98 9.4 13.5 1.9 1 1 1 2 2 2 0 Ion channel Vps51 PF08700.11 OQS07277.1 - 5.4e-08 32.8 0.6 2.1e-07 30.9 0.5 2.0 2 0 0 2 2 2 1 Vps51/Vps67 EF-hand_3 PF09069.11 OQS07277.1 - 0.77 10.2 3.1 3.3 8.2 0.2 3.1 2 1 1 3 3 3 0 EF-hand CHAD PF05235.14 OQS07277.1 - 2 8.3 4.9 0.63 10.0 1.8 1.7 2 0 0 2 2 2 0 CHAD domain PIP5K PF01504.18 OQS07278.1 - 4.7e-39 134.3 0.9 5.8e-30 104.4 0.0 2.6 2 1 1 3 3 3 2 Phosphatidylinositol-4-phosphate 5-Kinase PH PF00169.29 OQS07278.1 - 2.3e-11 44.1 0.0 7.7e-11 42.4 0.0 2.0 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 OQS07278.1 - 0.019 15.4 0.1 0.16 12.4 0.1 2.7 1 1 0 1 1 1 0 Pleckstrin homology domain 3HCDH_N PF02737.18 OQS07278.1 - 0.041 13.8 0.2 0.087 12.7 0.2 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pex24p PF06398.11 OQS07278.1 - 0.11 11.5 4.8 0.21 10.6 4.8 1.5 1 0 0 1 1 1 0 Integral peroxisomal membrane peroxin pPIWI_RE_REase PF18154.1 OQS07278.1 - 0.16 11.9 0.2 8.7 6.3 0.0 2.6 2 0 0 2 2 2 0 REase associating with pPIWI_RE Peptidase_M75 PF09375.10 OQS07278.1 - 0.18 11.3 0.5 0.32 10.4 0.5 1.3 1 0 0 1 1 1 0 Imelysin EF-hand_1 PF00036.32 OQS07279.1 - 3.6e-22 76.2 8.3 3e-05 23.2 0.1 5.4 5 0 0 5 5 5 4 EF hand EF-hand_7 PF13499.6 OQS07279.1 - 1.4e-20 73.5 10.0 6e-11 42.6 1.6 3.8 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_8 PF13833.6 OQS07279.1 - 7.3e-17 61.0 10.7 3.6e-05 23.5 0.3 5.8 3 2 2 5 5 5 4 EF-hand domain pair EF-hand_6 PF13405.6 OQS07279.1 - 3.2e-14 51.6 3.6 0.0049 16.7 0.1 5.1 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 OQS07279.1 - 1.8e-11 42.9 4.5 0.0021 17.5 0.0 5.1 5 0 0 5 5 5 3 EF hand EF-hand_4 PF12763.7 OQS07279.1 - 1.1e-06 28.6 5.9 6.3 6.8 0.1 5.4 3 2 2 5 5 5 1 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 OQS07279.1 - 1.8e-05 25.0 3.1 0.015 15.6 2.3 2.5 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region AKAP28 PF14469.6 OQS07279.1 - 0.00028 20.6 0.0 0.00055 19.7 0.0 1.5 1 0 0 1 1 1 1 28 kDa A-kinase anchor ToxS PF17323.2 OQS07279.1 - 0.00083 19.0 0.1 0.86 9.3 0.0 2.3 2 0 0 2 2 2 2 Trans-membrane regulatory protein ToxS EF-hand_11 PF08976.11 OQS07279.1 - 0.03 15.2 0.3 9.2 7.2 0.0 2.8 2 0 0 2 2 2 0 EF-hand domain TM231 PF10149.9 OQS07279.1 - 0.051 12.9 2.0 0.053 12.9 0.4 1.8 2 0 0 2 2 2 0 Transmembrane protein 231 EF-hand_10 PF14788.6 OQS07279.1 - 0.46 10.4 4.2 1.4 8.8 0.5 3.4 3 2 2 5 5 5 0 EF hand Nop53 PF07767.11 OQS07280.1 - 7e-35 121.2 47.9 3.5e-34 118.9 41.4 3.0 2 1 0 2 2 2 1 Nop53 (60S ribosomal biogenesis) B2-adapt-app_C PF09066.10 OQS07280.1 - 1.7e-11 44.2 0.1 1.7e-11 44.2 0.1 2.3 2 0 0 2 2 2 1 Beta2-adaptin appendage, C-terminal sub-domain Spt5_N PF11942.8 OQS07280.1 - 3.3 8.8 15.1 0.48 11.4 7.1 2.8 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal DUF4291 PF14124.6 OQS07280.1 - 4 7.3 11.2 8.1 6.3 0.2 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4291) Ion_trans PF00520.31 OQS07281.1 - 1.2e-21 77.1 9.1 2.2e-21 76.2 9.1 1.4 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 OQS07281.1 - 1.3e-11 44.3 1.7 1.3e-11 44.3 1.7 2.1 2 0 0 2 2 2 1 Ion channel cNMP_binding PF00027.29 OQS07281.1 - 1.6e-11 44.1 0.0 6e-10 39.1 0.0 2.5 2 0 0 2 2 2 1 Cyclic nucleotide-binding domain Ion_trans PF00520.31 OQS07282.1 - 5e-25 88.1 15.2 8e-25 87.5 15.2 1.2 1 0 0 1 1 1 1 Ion transport protein WD40 PF00400.32 OQS07282.1 - 3.9e-16 59.2 0.1 2e-05 25.2 0.0 5.0 4 0 0 4 4 4 2 WD domain, G-beta repeat cNMP_binding PF00027.29 OQS07282.1 - 4.8e-09 36.2 0.0 5.4e-08 32.8 0.0 2.4 2 0 0 2 2 2 1 Cyclic nucleotide-binding domain Ion_trans_2 PF07885.16 OQS07282.1 - 1.5e-08 34.5 8.7 3.9e-08 33.1 8.7 1.7 1 0 0 1 1 1 1 Ion channel ANAPC4_WD40 PF12894.7 OQS07282.1 - 0.0002 21.6 2.4 0.37 11.1 0.0 5.0 4 2 1 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 OQS07282.1 - 0.0027 17.1 0.0 0.0072 15.7 0.0 1.7 1 1 0 1 1 1 1 WD40-like domain Ank PF00023.30 OQS07283.1 - 4.4e-20 71.2 5.0 3.7e-05 24.0 0.5 4.3 4 0 0 4 4 4 3 Ankyrin repeat Ank_2 PF12796.7 OQS07283.1 - 6.7e-20 71.5 12.5 2.2e-12 47.4 2.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQS07283.1 - 1.7e-17 63.5 3.1 4.4e-08 33.5 1.6 3.3 2 1 1 3 3 3 3 Ankyrin repeats (many copies) SAM_1 PF00536.30 OQS07283.1 - 6.3e-14 52.2 0.2 4.2e-12 46.3 0.0 2.3 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) Ank_3 PF13606.6 OQS07283.1 - 2.6e-13 48.8 3.2 0.008 16.6 0.3 4.4 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.6 OQS07283.1 - 1e-12 48.0 8.0 1.5e-09 37.9 2.4 3.2 2 1 1 3 3 3 2 Ankyrin repeats (many copies) SAM_2 PF07647.17 OQS07283.1 - 1.3e-09 38.0 0.1 5.6e-09 36.0 0.0 2.0 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SAM_3 PF18016.1 OQS07283.1 - 0.0024 17.6 0.1 0.014 15.2 0.0 2.1 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) fn3 PF00041.21 OQS07284.1 - 4.8e-48 161.4 0.0 1.5e-14 54.1 0.0 6.2 6 0 0 6 6 6 6 Fibronectin type III domain Pur_ac_phosph_N PF16656.5 OQS07284.1 - 3.6e-10 40.3 0.0 1 10.0 0.0 5.5 5 0 0 5 5 5 3 Purple acid Phosphatase, N-terminal domain Y_Y_Y PF07495.13 OQS07284.1 - 0.0027 17.6 0.0 21 5.2 0.0 4.6 4 0 0 4 4 4 1 Y_Y_Y domain DUF2369 PF10179.9 OQS07284.1 - 0.024 15.0 0.2 13 6.2 0.0 3.3 4 1 1 5 5 5 0 Uncharacterised conserved protein (DUF2369) Interfer-bind PF09294.10 OQS07284.1 - 0.036 14.4 0.0 5.5 7.4 0.0 2.8 2 0 0 2 2 2 0 Interferon-alpha/beta receptor, fibronectin type III Na_H_Exchanger PF00999.21 OQS07285.1 - 5.1e-51 173.6 45.4 6.3e-51 173.3 45.4 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family TFIID_20kDa PF03847.13 OQS07286.1 - 2.3e-19 69.6 0.0 4e-19 68.9 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A TFIID-31kDa PF02291.15 OQS07286.1 - 7.2e-06 26.1 0.5 2e-05 24.6 0.1 1.6 1 1 1 2 2 2 1 Transcription initiation factor IID, 31kD subunit CENP_C_N PF15622.6 OQS07286.1 - 0.011 15.3 0.2 0.012 15.1 0.2 1.1 1 0 0 1 1 1 0 Kinetochore assembly subunit CENP-C N-terminal Bromo_TP PF07524.13 OQS07286.1 - 0.025 14.6 0.0 0.038 14.0 0.0 1.4 1 0 0 1 1 1 0 Bromodomain associated MULE PF10551.9 OQS07287.1 - 0.00052 20.4 0.1 0.018 15.5 0.0 3.3 3 0 0 3 3 3 1 MULE transposase domain SWIM PF04434.17 OQS07287.1 - 0.00053 19.6 0.1 0.00053 19.6 0.1 2.8 3 0 0 3 3 3 1 SWIM zinc finger Pkinase PF00069.25 OQS07288.1 - 1.3e-89 300.0 6.6 3.6e-35 121.6 0.0 5.4 3 2 1 4 4 4 4 Protein kinase domain Pkinase_Tyr PF07714.17 OQS07288.1 - 1.6e-85 286.5 3.0 4.3e-32 111.4 0.0 5.4 3 2 2 5 5 5 4 Protein tyrosine kinase Kinase-like PF14531.6 OQS07288.1 - 0.0001 21.7 0.1 0.16 11.3 0.0 4.1 5 0 0 5 5 5 1 Kinase-like Kdo PF06293.14 OQS07288.1 - 0.00011 21.6 2.1 0.96 8.8 0.1 3.9 4 0 0 4 4 4 3 Lipopolysaccharide kinase (Kdo/WaaP) family Ank_5 PF13857.6 OQS07288.1 - 0.0017 18.6 0.0 0.008 16.5 0.0 2.2 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQS07288.1 - 0.003 17.9 0.0 0.018 15.5 0.0 2.5 1 0 0 1 1 1 1 Ankyrin repeat Ank_4 PF13637.6 OQS07288.1 - 0.022 15.3 0.0 0.071 13.7 0.0 1.9 1 0 0 1 1 1 0 Ankyrin repeats (many copies) SpmSyn_N PF17950.1 OQS07288.1 - 0.07 13.3 0.3 25 5.1 0.0 3.6 3 0 0 3 3 3 0 S-adenosylmethionine decarboxylase N -terminal Ank_2 PF12796.7 OQS07288.1 - 0.15 12.7 0.0 0.53 10.9 0.0 1.9 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) Ank_2 PF12796.7 OQS07289.1 - 1.1e-25 90.0 6.3 2.1e-11 44.2 0.1 3.6 2 1 2 4 4 4 3 Ankyrin repeats (3 copies) Ank PF00023.30 OQS07289.1 - 3.7e-17 61.9 5.2 0.0042 17.5 0.1 6.6 6 0 0 6 6 6 4 Ankyrin repeat Ank_3 PF13606.6 OQS07289.1 - 7.7e-17 59.7 2.0 0.0092 16.4 0.0 6.4 6 0 0 6 6 6 3 Ankyrin repeat Ank_4 PF13637.6 OQS07289.1 - 2.3e-16 59.9 3.9 1.6e-06 28.5 0.1 4.8 3 2 2 5 5 5 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 OQS07289.1 - 9.8e-15 54.4 3.8 0.0063 16.8 0.0 5.4 3 2 2 5 5 5 5 Ankyrin repeats (many copies) Methyltransf_25 PF13649.6 OQS07290.1 - 0.002 18.8 0.0 0.0043 17.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OQS07290.1 - 0.0034 17.2 0.0 0.0072 16.1 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain TRAPP PF04051.16 OQS07291.1 - 4.6e-35 120.5 0.1 5.4e-35 120.3 0.1 1.0 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component SAPS PF04499.15 OQS07292.1 - 4.3e-21 75.3 3.1 3.3e-14 52.5 0.0 3.4 1 1 2 3 3 3 3 SIT4 phosphatase-associated protein Ank_2 PF12796.7 OQS07293.1 - 5.2e-32 110.3 9.8 1.3e-14 54.5 0.7 3.1 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQS07293.1 - 2.5e-23 82.1 1.9 2.5e-08 34.3 0.0 3.4 3 0 0 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 OQS07293.1 - 9e-22 76.5 6.1 3.8e-05 23.9 0.1 6.2 7 0 0 7 7 7 4 Ankyrin repeat Ank_3 PF13606.6 OQS07293.1 - 1.3e-19 68.2 0.9 0.00057 20.1 0.0 5.5 6 0 0 6 6 6 4 Ankyrin repeat Ank_5 PF13857.6 OQS07293.1 - 6.3e-19 67.8 1.8 3.5e-06 27.2 0.1 4.2 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Usp PF00582.26 OQS07293.1 - 0.059 13.9 1.5 0.1 13.1 0.5 1.7 2 0 0 2 2 2 0 Universal stress protein family Vps36-NZF-N PF16988.5 OQS07293.1 - 0.7 9.3 2.9 1.8 8.0 2.9 1.7 1 1 0 1 1 1 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain Beach PF02138.18 OQS07294.1 - 7.2e-113 376.5 0.0 1e-112 376.0 0.0 1.2 1 0 0 1 1 1 1 Beige/BEACH domain LSM PF01423.22 OQS07294.1 - 2e-14 53.0 0.1 3.6e-14 52.2 0.1 1.4 1 0 0 1 1 1 1 LSM domain PH_BEACH PF14844.6 OQS07294.1 - 4.2e-12 46.0 0.0 2e-09 37.5 0.0 3.4 2 1 0 2 2 2 1 PH domain associated with Beige/BEACH WD40 PF00400.32 OQS07294.1 - 5.1e-12 46.1 18.2 0.0012 19.6 0.8 6.7 7 0 0 7 7 7 3 WD domain, G-beta repeat GRAM PF02893.20 OQS07294.1 - 3.6e-05 23.6 0.1 0.00036 20.4 0.0 2.4 2 0 0 2 2 2 1 GRAM domain SM-ATX PF14438.6 OQS07294.1 - 0.00061 19.9 0.0 0.0014 18.7 0.0 1.5 1 0 0 1 1 1 1 Ataxin 2 SM domain ANAPC4_WD40 PF12894.7 OQS07294.1 - 0.0013 19.0 0.0 1.2 9.5 0.0 4.0 2 1 2 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain PH_TFIIH PF08567.11 OQS07294.1 - 0.0024 18.1 0.0 0.023 15.0 0.0 2.5 3 0 0 3 3 3 1 TFIIH p62 subunit, N-terminal domain WD40_like PF17005.5 OQS07294.1 - 0.0067 15.8 0.5 0.027 13.8 0.1 2.3 3 1 0 3 3 3 1 WD40-like domain Cytochrom_D1 PF02239.16 OQS07294.1 - 0.053 12.0 0.0 0.42 9.1 0.0 2.0 2 0 0 2 2 2 0 Cytochrome D1 heme domain TB2_DP1_HVA22 PF03134.19 OQS07295.1 - 4.6e-30 103.4 4.4 7.4e-30 102.7 4.4 1.3 1 0 0 1 1 1 1 TB2/DP1, HVA22 family MT0933_antitox PF14013.6 OQS07295.1 - 0.0093 16.2 1.0 0.022 15.1 1.0 1.6 1 0 0 1 1 1 1 MT0933-like antitoxin protein DEAD PF00270.29 OQS07296.1 - 6.9e-48 162.7 1.6 3.2e-47 160.6 0.0 2.7 3 1 1 4 4 4 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OQS07296.1 - 2.1e-27 95.6 0.0 4.3e-26 91.4 0.0 2.8 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 OQS07296.1 - 3.3e-07 30.5 0.2 7.4e-07 29.3 0.0 1.7 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 OQS07296.1 - 0.015 15.6 0.3 0.084 13.1 0.1 2.3 2 1 0 2 2 2 0 AAA domain CCDC-167 PF15188.6 OQS07297.1 - 8.1e-08 32.5 23.0 3.4e-06 27.3 0.6 3.7 3 1 1 4 4 4 2 Coiled-coil domain-containing protein 167 Pox_A_type_inc PF04508.12 OQS07297.1 - 2.4e-05 24.0 7.8 0.018 14.8 0.8 3.2 2 0 0 2 2 2 2 Viral A-type inclusion protein repeat TSC22 PF01166.18 OQS07297.1 - 0.00063 20.0 0.5 0.00063 20.0 0.5 4.7 2 2 3 5 5 5 1 TSC-22/dip/bun family DUF4618 PF15397.6 OQS07297.1 - 0.0034 16.9 22.3 0.016 14.6 2.4 3.1 1 1 2 3 3 3 2 Domain of unknown function (DUF4618) bZIP_2 PF07716.15 OQS07297.1 - 0.014 15.5 5.7 0.014 15.5 5.7 4.3 4 0 0 4 4 4 0 Basic region leucine zipper DUF4094 PF13334.6 OQS07297.1 - 0.025 15.0 8.9 0.21 12.1 0.9 3.2 2 1 1 3 3 3 0 Domain of unknown function (DUF4094) DivIC PF04977.15 OQS07297.1 - 0.039 13.7 1.7 0.039 13.7 1.7 4.0 4 0 0 4 4 4 0 Septum formation initiator HR1 PF02185.16 OQS07297.1 - 0.064 13.4 31.9 0.09 12.9 4.5 4.0 4 0 0 4 4 4 0 Hr1 repeat LIFR_D2 PF17971.1 OQS07297.1 - 0.14 12.4 3.2 1.5 9.0 0.5 2.6 3 0 0 3 3 3 0 Leukemia inhibitory factor receptor D2 domain SIR4_SID PF16991.5 OQS07297.1 - 0.25 11.4 11.8 4.4 7.3 5.5 3.1 1 1 1 2 2 2 0 Sir4 SID domain Csm1_N PF18504.1 OQS07297.1 - 0.32 11.4 27.3 2.1 8.7 2.0 4.3 4 0 0 4 4 4 0 Csm1 N-terminal domain Phage_GP20 PF06810.11 OQS07297.1 - 0.75 9.6 13.4 3.4 7.5 5.8 2.6 2 1 0 2 2 2 0 Phage minor structural protein GP20 Seryl_tRNA_N PF02403.22 OQS07297.1 - 0.9 9.8 17.4 2.8 8.2 0.2 3.4 1 1 1 3 3 3 0 Seryl-tRNA synthetase N-terminal domain NPV_P10 PF05531.12 OQS07297.1 - 1.4 9.5 5.9 4.5 7.8 0.1 3.3 2 2 0 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF2730 PF10805.8 OQS07297.1 - 1.5 9.0 8.2 0.41 10.8 0.4 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF2730) Uso1_p115_C PF04871.13 OQS07297.1 - 2 8.8 23.6 2.2 8.6 2.3 3.0 1 1 2 3 3 3 0 Uso1 / p115 like vesicle tethering protein, C terminal region ABC_tran_CTD PF16326.5 OQS07297.1 - 2.5 8.4 22.5 0.29 11.4 1.0 3.9 3 1 1 4 4 4 0 ABC transporter C-terminal domain bZIP_1 PF00170.21 OQS07297.1 - 6.5 6.9 31.9 0.11 12.7 2.9 4.9 5 0 0 5 5 5 0 bZIP transcription factor DUF4140 PF13600.6 OQS07297.1 - 6.6 7.2 20.7 0.85 10.1 1.2 3.8 2 2 2 4 4 4 0 N-terminal domain of unknown function (DUF4140) Sec16 PF12932.7 OQS07297.1 - 6.7 7.3 6.9 16 6.1 0.2 2.8 1 1 0 2 2 2 0 Vesicle coat trafficking protein Sec16 mid-region HA PF03457.14 OQS07298.1 - 2.6e-26 91.7 8.7 7e-08 32.7 0.6 4.3 5 0 0 5 5 5 3 Helicase associated domain TFIIA PF03153.13 OQS07298.1 - 7.6 6.4 15.6 1.5 8.7 11.1 1.8 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Myb_DNA-binding PF00249.31 OQS07299.1 - 7e-10 38.9 0.2 1e-09 38.4 0.2 1.3 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OQS07299.1 - 0.0012 19.1 1.0 0.002 18.4 1.0 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain FYVE PF01363.21 OQS07300.1 - 8.7e-15 54.6 9.5 1.5e-14 53.9 9.5 1.4 1 0 0 1 1 1 1 FYVE zinc finger TPR_2 PF07719.17 OQS07300.1 - 7.5e-09 35.0 0.1 0.0012 18.8 0.0 3.8 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 OQS07300.1 - 3.2e-08 33.1 0.0 0.026 14.7 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 OQS07300.1 - 2.6e-07 30.9 9.3 4.8e-05 23.8 0.1 4.1 4 1 1 5 5 3 3 Tetratricopeptide repeat TPR_19 PF14559.6 OQS07300.1 - 7.7e-07 29.5 0.1 0.00025 21.5 0.0 2.6 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.6 OQS07300.1 - 8.6e-07 28.6 0.7 0.047 13.7 0.0 4.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.28 OQS07300.1 - 1.2e-06 28.1 0.0 0.012 15.4 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 OQS07300.1 - 3.7e-06 26.5 0.0 0.001 18.7 0.0 2.7 2 1 1 3 3 3 1 TPR repeat TPR_17 PF13431.6 OQS07300.1 - 6.3e-06 26.2 0.0 0.86 10.1 0.0 3.7 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 OQS07300.1 - 7.1e-06 26.2 4.8 0.0072 16.6 0.1 3.0 2 1 1 3 3 2 2 Tetratricopeptide repeat Ank_5 PF13857.6 OQS07300.1 - 8.5e-06 25.9 2.3 0.0045 17.3 0.2 3.1 3 0 0 3 3 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 OQS07300.1 - 4.2e-05 24.1 0.4 0.00034 21.1 0.2 2.1 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) TPR_21 PF09976.9 OQS07300.1 - 0.0001 22.1 0.0 0.00018 21.2 0.0 1.4 1 0 0 1 1 1 1 Tetratricopeptide repeat-like domain ANAPC3 PF12895.7 OQS07300.1 - 0.00032 20.9 0.0 0.0061 16.8 0.0 2.6 2 1 1 3 3 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.6 OQS07300.1 - 0.0005 19.9 0.6 4.8 7.2 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_20 PF14561.6 OQS07300.1 - 0.00063 20.0 0.1 0.0017 18.6 0.1 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_15 PF13429.6 OQS07300.1 - 0.00064 19.0 1.4 0.067 12.4 0.2 2.6 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 OQS07300.1 - 0.0024 18.5 1.0 3.2 8.5 0.0 3.3 2 1 0 3 3 3 1 Tetratricopeptide repeat Ank_3 PF13606.6 OQS07300.1 - 0.0031 17.9 1.1 0.64 10.8 0.0 3.2 3 0 0 3 3 2 1 Ankyrin repeat TPR_4 PF07721.14 OQS07300.1 - 0.0031 18.0 0.8 12 6.9 0.0 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat Ank_4 PF13637.6 OQS07300.1 - 0.019 15.6 0.9 4.7 7.9 0.1 2.8 2 1 1 3 3 2 0 Ankyrin repeats (many copies) TPR_6 PF13174.6 OQS07300.1 - 0.022 15.4 0.1 16 6.4 0.0 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat Afaf PF15339.6 OQS07300.1 - 0.09 12.5 0.0 0.15 11.8 0.0 1.2 1 0 0 1 1 1 0 Acrosome formation-associated factor Phage_Gp19 PF09355.10 OQS07300.1 - 0.097 13.1 0.3 0.53 10.7 0.0 2.0 2 0 0 2 2 2 0 Phage protein Gp19/Gp15/Gp42 DZR PF12773.7 OQS07300.1 - 1.8 8.7 6.6 4.8 7.3 6.6 1.7 1 1 0 1 1 1 0 Double zinc ribbon Pkinase_Tyr PF07714.17 OQS07301.1 - 1.7e-80 270.1 0.0 5.3e-42 143.9 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 OQS07301.1 - 1.5e-79 267.1 0.0 2.4e-42 145.1 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Kinase-like PF14531.6 OQS07301.1 - 6.4e-07 29.0 0.0 0.0062 15.9 0.0 2.7 3 0 0 3 3 3 2 Kinase-like APH PF01636.23 OQS07301.1 - 2.6e-05 24.2 1.6 0.047 13.6 0.0 3.2 3 1 0 3 3 3 2 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 OQS07301.1 - 0.0089 15.1 0.1 0.27 10.2 0.0 2.2 2 0 0 2 2 2 1 Seadornavirus VP7 DEP PF00610.21 OQS07301.1 - 0.022 14.8 0.0 0.05 13.7 0.0 1.6 1 0 0 1 1 1 0 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) DUF4791 PF16039.5 OQS07301.1 - 0.045 13.3 0.6 0.093 12.3 0.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4791) ABC1 PF03109.16 OQS07301.1 - 0.046 13.9 0.1 1.2 9.4 0.0 2.4 2 0 0 2 2 2 0 ABC1 family PDEase_I PF00233.19 OQS07302.1 - 4.8e-76 255.6 2.4 4.8e-76 255.6 2.4 1.7 2 0 0 2 2 2 1 3'5'-cyclic nucleotide phosphodiesterase Ion_trans PF00520.31 OQS07302.1 - 7.8e-07 28.6 5.5 1.3e-06 27.9 5.5 1.2 1 0 0 1 1 1 1 Ion transport protein C5HCH PF17982.1 OQS07302.1 - 0.013 15.7 8.3 0.013 15.7 8.3 4.4 5 0 0 5 5 5 0 NSD Cys-His rich domain Myb_DNA-binding PF00249.31 OQS07304.1 - 6.3e-08 32.7 0.1 9.7e-08 32.1 0.1 1.3 1 0 0 1 1 1 1 Myb-like DNA-binding domain Pannexin_like PF12534.8 OQS07304.1 - 0.017 14.2 0.5 0.02 14.0 0.5 1.1 1 0 0 1 1 1 0 Pannexin-like TM region of LRRC8 SnAPC_2_like PF11035.8 OQS07304.1 - 0.02 15.0 2.5 0.027 14.7 2.5 1.2 1 0 0 1 1 1 0 Small nuclear RNA activating complex subunit 2, SNAP190 Myb Myb_DNA-bind_6 PF13921.6 OQS07304.1 - 0.054 13.7 1.4 0.12 12.6 0.3 2.1 2 1 0 2 2 2 0 Myb-like DNA-binding domain MADF_DNA_bdg PF10545.9 OQS07304.1 - 0.1 12.9 2.7 0.34 11.2 1.2 2.1 2 0 0 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like zf_CCCH_4 PF18345.1 OQS07305.1 - 1.5e-06 28.0 2.6 4.5e-06 26.5 2.6 1.9 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH PF00642.24 OQS07305.1 - 0.024 14.5 0.3 0.024 14.5 0.3 1.9 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_3 PF15663.5 OQS07305.1 - 0.042 14.1 0.1 0.23 11.7 0.0 2.2 2 0 0 2 2 2 0 Zinc-finger containing family zf-CCCH_4 PF18044.1 OQS07305.1 - 1.7 8.5 5.9 0.29 11.0 1.9 1.8 2 0 0 2 2 2 0 CCCH-type zinc finger zf-CCCH_2 PF14608.6 OQS07305.1 - 3.5 8.2 11.0 0.14 12.6 3.5 2.7 3 0 0 3 3 3 0 RNA-binding, Nab2-type zinc finger RINGv PF12906.7 OQS07306.1 - 1.1e-14 54.3 6.6 3e-14 52.9 6.6 1.8 1 0 0 1 1 1 1 RING-variant domain zf-RING_2 PF13639.6 OQS07306.1 - 0.0049 17.2 4.5 0.011 16.0 4.5 1.7 1 0 0 1 1 1 1 Ring finger domain Zn_ribbon_17 PF17120.5 OQS07306.1 - 0.3 10.7 3.1 0.62 9.7 3.1 1.5 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type FANCL_C PF11793.8 OQS07306.1 - 0.56 10.4 2.5 1.2 9.4 2.5 1.5 1 0 0 1 1 1 0 FANCL C-terminal domain Kelch_5 PF13854.6 OQS07307.1 - 1.4e-30 104.7 4.2 2.5e-06 27.3 0.0 6.6 6 0 0 6 6 6 6 Kelch motif Kelch_3 PF13415.6 OQS07307.1 - 4.6e-27 93.7 9.2 6.4e-06 26.3 0.0 7.3 7 0 0 7 7 7 5 Galactose oxidase, central domain Kelch_4 PF13418.6 OQS07307.1 - 3.9e-22 78.0 8.8 1.6e-06 28.0 0.2 6.3 7 0 0 7 7 7 4 Galactose oxidase, central domain Kelch_1 PF01344.25 OQS07307.1 - 1.4e-15 56.6 13.9 0.00016 21.2 0.0 6.8 7 0 0 7 7 6 3 Kelch motif Kelch_6 PF13964.6 OQS07307.1 - 1.9e-15 56.5 16.8 0.0004 20.6 0.4 7.0 5 2 2 7 7 6 4 Kelch motif zf-RING_2 PF13639.6 OQS07307.1 - 3.4e-15 56.1 6.3 9.6e-15 54.7 6.3 1.9 1 0 0 1 1 1 1 Ring finger domain Kelch_2 PF07646.15 OQS07307.1 - 2.7e-12 46.1 5.9 0.0033 17.3 0.0 6.3 6 0 0 6 6 6 2 Kelch motif zf-rbx1 PF12678.7 OQS07307.1 - 1e-09 38.5 4.2 1e-09 38.5 4.2 2.4 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 OQS07307.1 - 1.4e-08 34.4 6.9 3.6e-08 33.1 6.9 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 OQS07307.1 - 1.7e-08 34.0 3.1 5.4e-08 32.4 3.1 1.9 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4 PF00097.25 OQS07307.1 - 1.2e-07 31.4 6.1 1.2e-07 31.4 6.1 1.9 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OQS07307.1 - 1.6e-07 31.2 3.7 1.6e-07 31.2 3.7 1.9 2 0 0 2 2 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 OQS07307.1 - 3.8e-06 26.7 3.0 3.8e-06 26.7 3.0 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OQS07307.1 - 5.9e-06 26.2 3.5 2e-05 24.5 3.5 2.0 1 0 0 1 1 1 1 RING-type zinc-finger zf-ANAPC11 PF12861.7 OQS07307.1 - 0.0016 18.4 6.7 0.0018 18.3 3.9 2.6 2 1 0 2 2 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.6 OQS07307.1 - 0.0017 18.2 6.7 0.0096 15.8 6.7 2.2 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 Zn_ribbon_17 PF17120.5 OQS07307.1 - 0.0031 17.1 2.6 0.0079 15.8 2.6 1.6 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type FANCL_C PF11793.8 OQS07307.1 - 0.0064 16.7 2.5 0.018 15.2 2.5 1.8 1 0 0 1 1 1 1 FANCL C-terminal domain RAG2 PF03089.14 OQS07307.1 - 0.048 12.6 0.0 0.65 8.9 0.0 2.6 3 0 0 3 3 3 0 Recombination activating protein 2 Malic_M PF03949.15 OQS07307.1 - 0.086 12.1 0.0 0.23 10.7 0.0 1.7 2 0 0 2 2 2 0 Malic enzyme, NAD binding domain RINGv PF12906.7 OQS07307.1 - 0.2 11.8 5.5 0.79 9.9 5.5 2.1 1 0 0 1 1 1 0 RING-variant domain zf-C3HC4_4 PF15227.6 OQS07307.1 - 0.78 9.9 8.9 0.24 11.6 5.3 2.2 2 0 0 2 2 1 0 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.6 OQS07307.1 - 1.1 9.1 6.5 2.6 7.9 6.5 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-Nse PF11789.8 OQS07307.1 - 1.2 9.1 3.5 2.7 7.9 3.5 1.6 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING-like PF08746.11 OQS07307.1 - 4.1 7.8 7.8 0.89 9.9 3.3 2.2 2 0 0 2 2 2 0 RING-like domain Ank_2 PF12796.7 OQS07308.1 - 1.8e-58 195.0 19.9 1.3e-09 38.5 0.0 11.5 6 4 6 12 12 12 11 Ankyrin repeats (3 copies) zf-TRAF PF02176.18 OQS07308.1 - 1.1e-44 151.0 239.7 1.1e-07 32.4 1.2 18.7 6 3 16 22 22 22 18 TRAF-type zinc finger Ank_4 PF13637.6 OQS07308.1 - 8.6e-43 144.2 17.1 3.7e-08 33.8 0.0 12.9 9 4 3 12 12 12 7 Ankyrin repeats (many copies) Ank PF00023.30 OQS07308.1 - 7.4e-38 127.4 18.4 0.022 15.2 0.0 14.3 13 0 0 13 13 13 11 Ankyrin repeat Ank_3 PF13606.6 OQS07308.1 - 2.3e-34 113.5 15.5 0.016 15.7 0.0 16.6 19 0 0 19 19 19 9 Ankyrin repeat Ank_5 PF13857.6 OQS07308.1 - 7.9e-34 115.3 16.5 2.8e-07 30.7 0.3 12.8 8 4 5 14 14 14 8 Ankyrin repeats (many copies) Ntox28 PF15605.6 OQS07308.1 - 0.078 13.2 3.5 4.2 7.7 0.2 3.0 2 0 0 2 2 2 0 Bacterial toxin 28 DUF713 PF05218.14 OQS07308.1 - 1 9.0 5.0 0.32 10.7 0.7 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF713) UCH PF00443.29 OQS07310.1 - 1.4e-44 152.6 0.0 2.6e-44 151.6 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP_var PF17807.1 OQS07310.1 - 4.7e-18 64.7 0.0 1.4e-17 63.2 0.0 1.9 1 0 0 1 1 1 1 Variant UBP zinc finger UBA PF00627.31 OQS07310.1 - 4.3e-16 58.4 0.2 2.1e-08 33.9 0.1 2.6 2 0 0 2 2 2 2 UBA/TS-N domain UCH_1 PF13423.6 OQS07310.1 - 3.4e-14 53.2 4.2 9.4e-11 41.9 1.0 2.9 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 OQS07310.1 - 1e-13 51.4 0.1 5.6e-13 49.0 0.0 2.2 2 0 0 2 2 2 1 Zn-finger in ubiquitin-hydrolases and other protein UBA_5 PF16577.5 OQS07310.1 - 0.065 13.4 0.0 0.21 11.8 0.0 1.8 1 0 0 1 1 1 0 UBA domain MMR_HSR1 PF01926.23 OQS07311.1 - 3.8e-07 30.2 0.0 1.6e-06 28.2 0.0 2.0 2 1 0 2 2 2 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 OQS07311.1 - 7.6e-07 29.3 2.3 2.2e-06 27.9 0.1 2.7 1 1 2 3 3 3 1 Dynamin family Tex_N PF09371.10 OQS07311.1 - 0.00031 20.5 0.3 0.00053 19.7 0.3 1.3 1 0 0 1 1 1 1 Tex-like protein N-terminal domain Septin PF00735.18 OQS07311.1 - 0.0056 16.0 0.9 0.28 10.4 0.0 2.5 2 0 0 2 2 2 1 Septin Cas_St_Csn2 PF16813.5 OQS07311.1 - 0.012 14.7 0.1 0.025 13.7 0.1 1.4 1 0 0 1 1 1 0 CRISPR-associated protein Csn2 subfamily St Roc PF08477.13 OQS07311.1 - 0.019 15.2 0.1 0.053 13.8 0.1 1.8 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase RsgA_GTPase PF03193.16 OQS07311.1 - 0.059 13.3 4.9 0.097 12.6 0.0 2.9 3 1 0 3 3 3 0 RsgA GTPase PMC2NT PF08066.12 OQS07311.1 - 0.13 13.0 0.8 14 6.5 0.0 3.1 2 1 1 3 3 3 0 PMC2NT (NUC016) domain Muted PF14942.6 OQS07311.1 - 1.5 9.1 8.5 0.14 12.5 3.3 1.8 2 0 0 2 2 2 0 Organelle biogenesis, Muted-like protein Peptidase_C1 PF00112.23 OQS07312.1 - 7.6e-61 206.0 10.0 1.2e-60 205.3 10.0 1.3 1 0 0 1 1 1 1 Papain family cysteine protease PT PF04886.12 OQS07312.1 - 1.3e-09 37.4 27.8 4.6e-07 29.3 14.3 2.7 2 1 1 3 3 3 2 PT repeat Peptidase_C1_2 PF03051.15 OQS07312.1 - 0.00027 19.8 1.5 0.13 11.0 0.0 2.2 2 0 0 2 2 2 2 Peptidase C1-like family Ank_2 PF12796.7 OQS07313.1 - 4.5e-21 75.2 12.2 5.1e-06 27.0 1.4 4.7 2 2 0 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQS07313.1 - 1.2e-19 70.4 8.8 0.0012 19.4 0.1 6.8 3 2 2 6 6 6 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 OQS07313.1 - 2.9e-18 65.7 13.0 8.7e-05 22.7 0.0 7.8 3 2 5 9 9 9 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQS07313.1 - 3.4e-12 45.4 8.9 0.76 10.5 0.0 8.8 7 2 2 9 9 9 3 Ankyrin repeat DUF5049 PF16468.5 OQS07313.1 - 0.00021 21.1 4.1 27 4.8 0.0 6.0 8 0 0 8 8 8 0 Domain of unknown function (DUF5049) Ank PF00023.30 OQS07313.1 - 0.00027 21.2 1.0 11 6.7 0.3 5.9 3 2 1 4 4 4 1 Ankyrin repeat HECA PF15353.6 OQS07313.1 - 0.035 14.4 3.6 0.061 13.6 0.2 3.0 3 1 0 3 3 3 0 Headcase protein family homologue Vps23_core PF09454.10 OQS07313.1 - 0.13 12.2 0.0 43 4.2 0.0 3.7 3 0 0 3 3 3 0 Vps23 core domain Cpn60_TCP1 PF00118.24 OQS07315.1 - 1.6e-150 502.0 17.0 2.4e-150 501.4 17.0 1.3 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF1619 PF07773.11 OQS07315.1 - 1.2e-34 120.6 10.3 3.7e-32 112.5 4.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF1619) Hydrolase_4 PF12146.8 OQS07315.1 - 1.7e-07 30.8 0.0 0.00037 19.9 0.0 2.5 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 OQS07315.1 - 0.0041 17.7 0.0 0.0071 17.0 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 OQS07315.1 - 0.076 12.7 0.2 0.57 9.8 0.1 2.1 2 0 0 2 2 2 0 alpha/beta hydrolase fold PhoPQ_related PF10142.9 OQS07315.1 - 0.095 11.3 0.0 0.2 10.3 0.0 1.4 1 0 0 1 1 1 0 PhoPQ-activated pathogenicity-related protein WD40 PF00400.32 OQS07316.1 - 2.2e-08 34.6 5.1 0.65 11.0 0.4 6.2 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OQS07316.1 - 0.001 19.3 0.0 7.3 7.0 0.0 4.2 3 1 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain PCP_red PF08369.10 OQS07316.1 - 0.13 12.4 0.0 0.23 11.7 0.0 1.4 1 0 0 1 1 1 0 Proto-chlorophyllide reductase 57 kD subunit Mcl1_mid PF12341.8 OQS07317.1 - 0.0011 18.3 0.1 0.0017 17.8 0.1 1.3 1 0 0 1 1 1 1 Minichromosome loss protein, Mcl1, middle region PQQ_2 PF13360.6 OQS07317.1 - 0.076 12.6 0.1 0.44 10.1 0.1 2.3 1 1 0 1 1 1 0 PQQ-like domain WD40_like PF17005.5 OQS07317.1 - 0.19 11.0 4.3 9.1 5.5 0.3 3.3 2 2 2 4 4 4 0 WD40-like domain TMEM154 PF15102.6 OQS07318.1 - 0.37 10.7 9.1 2 8.3 9.1 2.3 1 1 0 1 1 1 0 TMEM154 protein family zf-HIT PF04438.16 OQS07320.1 - 2.4e-10 40.1 13.1 3.4e-10 39.6 13.1 1.2 1 0 0 1 1 1 1 HIT zinc finger Shisa PF13908.6 OQS07320.1 - 0.24 11.6 6.1 0.45 10.7 6.1 1.6 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator zf-MYND PF01753.18 OQS07320.1 - 0.35 11.0 12.4 0.58 10.3 12.4 1.4 1 0 0 1 1 1 0 MYND finger Ribonuclease_3 PF00636.26 OQS07321.1 - 3.8e-29 101.4 0.0 2.3e-13 50.7 0.0 2.9 2 0 0 2 2 2 2 Ribonuclease III domain Dicer_dimer PF03368.14 OQS07321.1 - 1.3e-16 60.5 0.9 2.1e-15 56.7 0.0 3.0 3 0 0 3 3 3 1 Dicer dimerisation domain Ribonucleas_3_3 PF14622.6 OQS07321.1 - 5.2e-14 52.5 0.0 2e-05 24.8 0.0 3.5 2 1 0 2 2 2 2 Ribonuclease-III-like Rpr2 PF04032.16 OQS07321.1 - 1e-09 38.6 1.6 2.3e-09 37.4 1.6 1.7 1 0 0 1 1 1 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain DUF4674 PF15719.5 OQS07321.1 - 0.69 9.9 4.1 1.4 9.0 4.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4674) PfkB PF00294.24 OQS07322.1 - 8e-52 176.4 0.0 9e-52 176.2 0.0 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.12 OQS07322.1 - 0.061 12.7 0.2 0.16 11.4 0.2 1.7 1 1 0 1 1 1 0 Phosphomethylpyrimidine kinase Cullin PF00888.22 OQS07323.1 - 1.6e-22 79.9 0.2 5.3e-22 78.2 0.3 1.7 2 0 0 2 2 2 1 Cullin family ANAPC2 PF08672.11 OQS07323.1 - 8.4e-18 64.6 0.0 4e-17 62.5 0.0 2.3 1 0 0 1 1 1 1 Anaphase promoting complex (APC) subunit 2 RNase_Zc3h12a PF11977.8 OQS07324.1 - 2.4e-18 66.4 0.0 5.1e-18 65.3 0.0 1.5 1 0 0 1 1 1 1 Zc3h12a-like Ribonuclease NYN domain PRORP PF16953.5 OQS07324.1 - 7.8e-06 25.6 2.7 5.7e-05 22.7 0.1 2.6 3 0 0 3 3 3 1 Protein-only RNase P ANAPC3 PF12895.7 OQS07324.1 - 0.069 13.4 0.8 1.6 9.0 0.1 3.4 3 1 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_1 PF00515.28 OQS07324.1 - 0.12 12.2 0.3 17 5.5 0.0 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF5615 PF18480.1 OQS07324.1 - 0.16 11.8 0.1 0.4 10.5 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF5615) Ino80_Iec3 PF14612.6 OQS07326.1 - 0.051 14.2 0.6 0.072 13.8 0.6 1.2 1 0 0 1 1 1 0 IEC3 subunit of the Ino80 complex, chromatin re-modelling SWI2_SNF2 PF18766.1 OQS07327.1 - 7.6e-27 94.4 5.7 1.4e-26 93.6 5.7 1.4 1 0 0 1 1 1 1 SWI2/SNF2 ATPase DENN PF02141.21 OQS07327.1 - 5.8e-22 78.5 3.2 3.5e-21 76.0 3.2 2.4 1 0 0 1 1 1 1 DENN (AEX-3) domain ResIII PF04851.15 OQS07327.1 - 2.6e-21 76.4 1.9 8e-21 74.8 1.4 2.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.29 OQS07327.1 - 2.6e-12 46.9 2.6 5.5e-12 45.8 2.6 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase WW PF00397.26 OQS07327.1 - 2.2e-08 34.1 0.5 4.1e-08 33.2 0.5 1.5 1 0 0 1 1 1 1 WW domain uDENN PF03456.18 OQS07327.1 - 7.9e-06 26.5 0.6 2.4e-05 25.0 0.6 1.9 1 0 0 1 1 1 1 uDENN domain DUF2075 PF09848.9 OQS07327.1 - 0.018 14.3 0.8 0.033 13.4 0.8 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) 5_3_exonuc_N PF02739.16 OQS07327.1 - 0.075 12.9 0.3 0.21 11.5 0.3 1.7 1 0 0 1 1 1 0 5'-3' exonuclease, N-terminal resolvase-like domain Rib_recp_KP_reg PF05104.12 OQS07327.1 - 0.33 12.0 7.1 0.73 10.9 7.1 1.5 1 0 0 1 1 1 0 Ribosome receptor lysine/proline rich region WD40 PF00400.32 OQS07328.1 - 1e-10 42.0 6.3 0.0067 17.2 0.2 6.5 8 0 0 8 8 8 3 WD domain, G-beta repeat MPS2 PF17060.5 OQS07328.1 - 0.0002 20.8 11.9 0.0002 20.8 11.9 4.1 2 1 2 4 4 4 1 Monopolar spindle protein 2 ANAPC4_WD40 PF12894.7 OQS07328.1 - 0.0014 18.9 0.0 2.3 8.6 0.0 4.6 4 0 0 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain Gly-zipper_Omp PF13488.6 OQS07329.1 - 0.022 14.8 9.8 0.022 14.8 9.8 3.3 3 1 1 4 4 4 0 Glycine zipper ELO PF01151.18 OQS07330.1 - 4.9e-45 154.0 20.4 5.9e-45 153.8 20.4 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family LBR_tudor PF09465.10 OQS07331.1 - 9.4e-09 35.0 1.2 1.6e-05 24.6 0.2 2.1 2 0 0 2 2 2 2 Lamin-B receptor of TUDOR domain TUDOR_5 PF18359.1 OQS07331.1 - 1e-08 34.8 6.6 4.4e-06 26.3 0.9 2.4 2 1 0 2 2 2 2 Histone methyltransferase Tudor domain 1 Agenet PF05641.12 OQS07331.1 - 1.3e-08 35.2 0.3 0.00013 22.4 0.0 2.6 2 1 0 2 2 2 2 Agenet domain Tudor_3 PF18115.1 OQS07331.1 - 5.9e-05 22.8 0.0 0.037 13.9 0.0 2.3 2 0 0 2 2 2 2 DNA repair protein Crb2 Tudor domain DUF1325 PF07039.11 OQS07331.1 - 0.015 15.4 0.0 0.063 13.4 0.0 1.8 1 1 1 2 2 2 0 SGF29 tudor-like domain Tudor_2 PF18104.1 OQS07331.1 - 0.016 14.9 3.3 0.15 11.8 0.9 2.5 2 1 0 2 2 2 0 Jumonji domain-containing protein 2A Tudor domain DUF4994 PF16385.5 OQS07331.1 - 0.03 14.2 0.0 0.29 11.1 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function DUF4537 PF15057.6 OQS07331.1 - 0.09 12.8 0.3 2.9 7.9 0.1 1.8 1 1 0 2 2 2 0 Domain of unknown function (DUF4537) Pkinase PF00069.25 OQS07332.1 - 1.2e-49 169.1 0.0 1.9e-49 168.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQS07332.1 - 2.9e-16 59.5 0.0 9.4e-16 57.9 0.0 1.9 2 1 0 2 2 2 1 Protein tyrosine kinase eIF3g PF12353.8 OQS07332.1 - 1e-11 45.3 43.0 0.00075 19.9 0.2 7.3 4 1 3 7 7 7 5 Eukaryotic translation initiation factor 3 subunit G DUF1752 PF08550.10 OQS07332.1 - 1.3e-07 31.3 1.9 2.6e-07 30.3 1.9 1.6 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) PH PF00169.29 OQS07332.1 - 2.7e-07 31.0 0.5 8e-07 29.5 0.4 1.9 2 0 0 2 2 2 1 PH domain ADK_lid PF05191.14 OQS07332.1 - 0.096 12.7 8.5 2.5 8.2 1.1 4.6 4 2 0 4 4 4 0 Adenylate kinase, active site lid CEBP_ZZ PF16366.5 OQS07332.1 - 0.57 10.5 19.9 0.28 11.4 7.8 4.1 3 0 0 3 3 3 0 Cytoplasmic polyadenylation element-binding protein ZZ domain DUF3535 PF12054.8 OQS07333.1 - 0.061 12.6 0.6 0.12 11.5 0.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3535) Mito_carr PF00153.27 OQS07335.1 - 1.1e-52 175.9 2.0 4.2e-17 61.9 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein FYVE PF01363.21 OQS07336.1 - 1.4e-23 82.7 52.0 1e-09 38.4 15.7 3.9 3 0 0 3 3 3 3 FYVE zinc finger START PF01852.19 OQS07336.1 - 6.5e-11 42.0 0.2 1.1e-08 34.8 0.2 2.3 2 0 0 2 2 2 2 START domain FYVE_2 PF02318.16 OQS07336.1 - 4.3e-05 23.7 7.2 4.3e-05 23.7 7.2 3.6 3 0 0 3 3 3 2 FYVE-type zinc finger C1_2 PF03107.16 OQS07336.1 - 0.21 11.9 30.5 0.19 12.1 4.2 4.4 4 0 0 4 4 4 0 C1 domain DUF2315 PF10231.9 OQS07336.1 - 0.34 11.0 2.1 0.36 11.0 0.2 2.0 2 0 0 2 2 2 0 Apoptogenic protein 1 Extensin_1 PF02095.15 OQS07336.1 - 0.66 10.3 5.4 1.9 8.9 5.4 1.9 1 0 0 1 1 1 0 Extensin-like protein repeat TauD PF02668.16 OQS07337.1 - 3.4e-21 76.2 0.1 5.2e-21 75.6 0.1 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF971 PF06155.12 OQS07337.1 - 7.3e-12 45.8 0.2 3.9e-11 43.4 0.1 2.0 1 1 1 2 2 2 2 Protein of unknown function (DUF971) Phosphodiest PF01663.22 OQS07338.1 - 8.5e-14 51.9 3.9 1.8e-10 40.9 0.6 2.2 1 1 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 OQS07338.1 - 0.00012 21.6 0.0 0.41 10.0 0.0 2.2 2 0 0 2 2 2 2 Sulfatase Na_Ca_ex PF01699.24 OQS07341.1 - 2.7e-43 147.5 36.7 1.9e-24 86.4 15.7 2.7 2 0 0 2 2 2 2 Sodium/calcium exchanger protein eIF-5a PF01287.20 OQS07342.1 - 1.9e-23 82.3 0.0 2.7e-23 81.8 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold EFP_N PF08207.12 OQS07342.1 - 2.1e-05 24.4 0.1 3e-05 23.9 0.1 1.3 1 0 0 1 1 1 1 Elongation factor P (EF-P) KOW-like domain Nkap_C PF06047.11 OQS07343.1 - 4.3e-46 155.2 3.7 4.3e-46 155.2 3.7 2.5 2 0 0 2 2 2 1 NF-kappa-B-activating protein C-terminal domain DUF4746 PF15928.5 OQS07343.1 - 0.41 10.0 15.4 0.055 12.9 10.4 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4746) SAPS PF04499.15 OQS07343.1 - 1.5 7.5 10.8 2.5 6.8 10.8 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein PRP38 PF03371.15 OQS07344.1 - 1.9e-55 187.4 0.4 2.9e-55 186.8 0.4 1.3 1 0 0 1 1 1 1 PRP38 family DAO PF01266.24 OQS07345.1 - 1.8e-42 146.2 1.0 6.8e-42 144.3 1.0 1.7 1 1 0 1 1 1 1 FAD dependent oxidoreductase TrkA_N PF02254.18 OQS07345.1 - 0.0017 18.6 0.1 0.0033 17.7 0.1 1.5 1 0 0 1 1 1 1 TrkA-N domain Pyr_redox_2 PF07992.14 OQS07345.1 - 0.0089 15.3 0.1 0.018 14.3 0.1 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 OQS07345.1 - 0.011 15.0 0.4 0.036 13.3 0.3 1.7 2 0 0 2 2 2 0 FAD binding domain NAD_binding_8 PF13450.6 OQS07345.1 - 0.016 15.5 0.2 0.046 13.9 0.2 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain 3HCDH_N PF02737.18 OQS07345.1 - 0.02 14.8 0.1 0.036 13.9 0.1 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Lipase_3 PF01764.25 OQS07346.1 - 1.9e-07 31.0 1.1 3.1e-07 30.4 0.0 1.9 2 0 0 2 2 2 1 Lipase (class 3) IIGP PF05049.13 OQS07346.1 - 0.0017 17.5 0.0 0.0065 15.6 0.0 1.8 2 0 0 2 2 2 1 Interferon-inducible GTPase (IIGP) MMR_HSR1 PF01926.23 OQS07346.1 - 0.0055 16.8 0.0 0.021 14.9 0.0 2.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_22 PF13401.6 OQS07346.1 - 0.0082 16.4 0.0 0.028 14.7 0.0 1.9 1 0 0 1 1 1 1 AAA domain Dynamin_N PF00350.23 OQS07346.1 - 0.0092 16.0 0.2 0.18 11.9 0.0 2.5 1 1 1 2 2 2 1 Dynamin family SRPRB PF09439.10 OQS07346.1 - 0.045 13.2 0.0 0.11 12.0 0.0 1.6 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit WD40 PF00400.32 OQS07348.1 - 3.6e-09 37.1 14.3 0.01 16.6 0.1 6.2 6 1 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OQS07348.1 - 8.2e-09 35.7 0.1 0.017 15.4 0.0 4.2 2 1 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain PQQ_2 PF13360.6 OQS07348.1 - 0.00062 19.4 0.2 0.0067 16.0 0.0 2.3 3 0 0 3 3 3 1 PQQ-like domain PQQ_3 PF13570.6 OQS07348.1 - 0.003 18.0 0.0 1.9 9.1 0.0 3.8 3 1 0 3 3 3 1 PQQ-like domain dUTPase PF00692.19 OQS07349.1 - 5.5e-44 149.0 0.0 7.1e-44 148.6 0.0 1.1 1 0 0 1 1 1 1 dUTPase DUF3037 PF11236.8 OQS07349.1 - 0.17 12.4 0.7 0.96 9.9 0.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3037) Voltage_CLC PF00654.20 OQS07350.1 - 3.3e-79 266.7 29.9 3.3e-79 266.7 29.9 3.8 3 1 0 4 4 4 1 Voltage gated chloride channel AA_permease_2 PF13520.6 OQS07350.1 - 1.9e-44 152.2 33.2 1.9e-44 152.2 33.2 3.6 3 1 0 3 3 3 1 Amino acid permease AA_permease PF00324.21 OQS07350.1 - 1.2e-31 109.9 31.0 1.2e-31 109.9 31.0 2.6 3 0 0 3 3 3 1 Amino acid permease AA_permease_C PF13906.6 OQS07350.1 - 1.5e-10 41.0 2.9 1.5e-10 41.0 2.9 3.4 3 0 0 3 3 3 1 C-terminus of AA_permease CBS PF00571.28 OQS07350.1 - 0.0002 21.8 0.7 0.31 11.5 0.1 2.5 2 0 0 2 2 2 2 CBS domain AcrZ PF10766.9 OQS07350.1 - 6.8 6.3 6.7 14 5.3 0.1 3.5 3 0 0 3 3 3 0 Multidrug efflux pump-associated protein AcrZ LRR_6 PF13516.6 OQS07351.1 - 6.1e-15 53.9 7.9 0.00016 21.4 0.0 5.4 5 0 0 5 5 5 4 Leucine Rich repeat LRR_1 PF00560.33 OQS07351.1 - 0.0094 16.4 0.1 49 5.0 0.0 4.6 4 0 0 4 4 4 0 Leucine Rich Repeat ANAPC4_WD40 PF12894.7 OQS07351.1 - 0.012 15.9 0.0 0.79 10.1 0.0 3.1 1 1 1 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 OQS07351.1 - 0.1 13.5 1.1 3.8 8.5 0.0 3.8 5 0 0 5 5 5 0 WD domain, G-beta repeat LRR_8 PF13855.6 OQS07351.1 - 9.3 6.1 8.0 3.2 7.6 0.6 3.4 2 1 2 4 4 4 0 Leucine rich repeat CCT PF06203.14 OQS07352.1 - 1.3e-08 34.7 9.2 2.1e-08 34.1 9.2 1.2 1 0 0 1 1 1 1 CCT motif DUF4355 PF14265.6 OQS07352.1 - 0.085 13.1 1.6 0.13 12.5 1.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4355) Pkinase PF00069.25 OQS07353.1 - 5e-42 144.1 0.0 1.1e-41 142.9 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQS07353.1 - 1.8e-29 102.9 0.0 3e-29 102.1 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OQS07353.1 - 1.4e-05 24.5 0.0 2.9e-05 23.5 0.0 1.4 1 1 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 OQS07353.1 - 0.0015 17.4 0.1 0.014 14.2 0.0 1.9 1 1 0 2 2 2 1 Fungal protein kinase zf-C3HC4 PF00097.25 OQS07353.1 - 0.015 15.2 8.4 0.032 14.1 8.4 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) TerY_C PF15616.6 OQS07353.1 - 0.11 12.6 1.1 0.31 11.1 1.1 1.7 1 0 0 1 1 1 0 TerY-C metal binding domain APH PF01636.23 OQS07353.1 - 0.16 11.9 0.0 0.27 11.1 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Prok-RING_4 PF14447.6 OQS07353.1 - 0.43 10.5 7.4 0.94 9.4 7.4 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 OQS07353.1 - 0.45 10.4 9.2 2.4 8.1 9.2 2.2 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 OQS07353.1 - 0.54 10.6 7.1 2.8 8.4 7.4 2.1 1 1 1 2 2 2 0 Ring finger domain zf-RING_5 PF14634.6 OQS07353.1 - 1.7 8.7 8.4 3.6 7.6 8.4 1.6 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_4 PF15227.6 OQS07353.1 - 5.2 7.3 8.1 10 6.4 8.1 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING GAF PF01590.26 OQS07354.1 - 3e-28 99.1 4.6 1.8e-08 35.1 0.1 3.7 3 0 0 3 3 3 3 GAF domain GAF_2 PF13185.6 OQS07354.1 - 7.7e-21 74.8 0.2 7.8e-07 29.5 0.1 3.7 3 0 0 3 3 3 3 GAF domain FYVE PF01363.21 OQS07354.1 - 1.1e-20 73.6 48.9 1.7e-12 47.3 11.2 3.8 4 0 0 4 4 4 2 FYVE zinc finger GAF_3 PF13492.6 OQS07354.1 - 4e-11 43.4 0.6 0.00045 20.6 0.0 3.8 3 0 0 3 3 3 3 GAF domain SpoVT_C PF15714.5 OQS07354.1 - 0.006 16.6 0.0 0.35 10.9 0.0 3.1 3 0 0 3 3 3 1 Stage V sporulation protein T C-terminal, transcription factor FYVE_2 PF02318.16 OQS07354.1 - 8.5 6.6 30.7 4.5 7.5 13.9 2.7 2 0 0 2 2 2 0 FYVE-type zinc finger GMP_PDE_delta PF05351.11 OQS07355.1 - 5.1e-33 114.4 0.4 5.1e-33 114.4 0.4 1.7 2 0 0 2 2 2 1 GMP-PDE, delta subunit NifU_N PF01592.16 OQS07355.1 - 0.06 13.5 0.0 0.1 12.7 0.0 1.3 1 0 0 1 1 1 0 NifU-like N terminal domain WD40 PF00400.32 OQS07356.1 - 2.2e-25 88.4 16.5 0.00016 22.4 0.0 8.0 7 0 0 7 7 7 6 WD domain, G-beta repeat Peptidase_M20 PF01546.28 OQS07356.1 - 8.8e-22 77.8 0.0 8.9e-21 74.5 0.0 2.2 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 OQS07356.1 - 6.6e-07 29.2 0.0 1.4e-06 28.2 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain Exo_endo_phos PF03372.23 OQS07356.1 - 3.8e-05 23.3 0.0 0.00011 21.9 0.0 1.8 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Nup160 PF11715.8 OQS07356.1 - 0.0017 17.1 10.6 1.5 7.4 0.1 4.9 3 2 3 6 6 6 3 Nucleoporin Nup120/160 Exo_endo_phos_2 PF14529.6 OQS07356.1 - 0.02 14.7 0.5 0.12 12.2 0.0 2.4 2 0 0 2 2 2 0 Endonuclease-reverse transcriptase RasGEF_N_2 PF14663.6 OQS07356.1 - 0.041 14.3 0.1 0.14 12.5 0.0 1.9 2 0 0 2 2 2 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain RRM_1 PF00076.22 OQS07357.1 - 1.4e-19 69.6 0.1 2.9e-19 68.7 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) U1snRNP70_N PF12220.8 OQS07357.1 - 6e-17 62.1 6.3 6e-17 62.1 6.3 2.1 2 1 0 2 2 2 1 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal RRM_5 PF13893.6 OQS07357.1 - 0.02 14.5 0.0 0.032 13.8 0.0 1.2 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 OQS07357.1 - 0.024 14.5 0.0 0.041 13.7 0.0 1.3 1 0 0 1 1 1 0 Occluded RNA-recognition motif RRM_7 PF16367.5 OQS07357.1 - 0.057 13.5 0.0 0.17 12.0 0.0 1.8 1 1 0 1 1 1 0 RNA recognition motif RL PF17797.1 OQS07357.1 - 0.15 12.1 0.1 0.28 11.1 0.1 1.4 1 0 0 1 1 1 0 RL domain CS PF04969.16 OQS07358.1 - 1.5e-06 29.1 0.4 3e-06 28.1 0.4 1.5 1 0 0 1 1 1 1 CS domain SGS PF05002.15 OQS07358.1 - 0.0012 18.9 1.4 0.0026 17.8 1.4 1.5 1 0 0 1 1 1 1 SGS domain PolyA_pol_RNAbd PF12627.7 OQS07358.1 - 0.024 14.4 0.1 0.041 13.6 0.1 1.4 1 0 0 1 1 1 0 Probable RNA and SrmB- binding site of polymerase A Kinesin PF00225.23 OQS07359.1 - 2.4e-110 368.6 2.9 2.4e-110 368.6 2.9 2.3 2 0 0 2 2 2 1 Kinesin motor domain NMT PF01233.19 OQS07359.1 - 8.2e-75 250.0 0.0 2.2e-74 248.6 0.0 1.8 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain NMT_C PF02799.15 OQS07359.1 - 2.2e-73 246.2 0.0 6.8e-73 244.6 0.0 1.9 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain Microtub_bd PF16796.5 OQS07359.1 - 1.6e-45 154.7 0.4 4.7e-45 153.2 0.4 1.9 1 0 0 1 1 1 1 Microtubule binding Acetyltransf_9 PF13527.7 OQS07359.1 - 0.021 14.9 0.0 0.053 13.6 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain eIF-5a PF01287.20 OQS07360.1 - 0.0052 16.9 0.2 0.016 15.3 0.1 1.8 2 0 0 2 2 2 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold CK_II_beta PF01214.18 OQS07361.1 - 2.4e-67 226.3 0.0 3.1e-67 225.9 0.0 1.1 1 0 0 1 1 1 1 Casein kinase II regulatory subunit IBR PF01485.21 OQS07361.1 - 0.064 13.5 0.1 0.13 12.5 0.1 1.5 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain STAG PF08514.11 OQS07362.1 - 2.4e-24 85.4 0.0 2.4e-24 85.4 0.0 3.3 3 0 0 3 3 3 1 STAG domain HEAT_2 PF13646.6 OQS07362.1 - 3.3e-06 27.4 0.9 0.0028 18.0 0.0 3.9 3 1 1 4 4 4 2 HEAT repeats HEAT PF02985.22 OQS07362.1 - 0.00021 21.3 0.1 0.51 10.7 0.0 4.6 3 0 0 3 3 3 1 HEAT repeat HEAT_EZ PF13513.6 OQS07362.1 - 0.17 12.4 0.5 1.1 9.9 0.0 2.8 3 0 0 3 3 3 0 HEAT-like repeat PDZ PF00595.24 OQS07363.1 - 1.4e-35 121.5 5.4 0.00013 22.2 0.0 7.3 7 0 0 7 7 7 7 PDZ domain PDZ_6 PF17820.1 OQS07363.1 - 5.6e-27 93.3 3.6 0.00013 21.8 0.0 7.5 7 0 0 7 7 7 7 PDZ domain PDZ_2 PF13180.6 OQS07363.1 - 4.8e-09 36.4 14.2 0.046 14.0 0.1 6.8 7 0 0 7 7 7 5 PDZ domain Apt1 PF10351.9 OQS07364.1 - 4.6e-34 118.1 1.1 5.5e-32 111.2 1.1 2.3 1 1 0 1 1 1 1 Golgi-body localisation protein domain Fmp27_GFWDK PF10347.9 OQS07364.1 - 0.00022 21.4 0.0 0.00054 20.1 0.0 1.7 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain Tenui_N PF05733.11 OQS07364.1 - 1.2 8.6 4.1 17 4.9 0.0 2.7 3 0 0 3 3 3 0 Tenuivirus/Phlebovirus nucleocapsid protein AAA PF00004.29 OQS07365.1 - 5.2e-59 198.4 0.0 2e-44 151.2 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 OQS07365.1 - 4.8e-12 46.6 0.1 0.00095 19.6 0.0 3.8 3 0 0 3 3 3 2 AAA ATPase domain RuvB_N PF05496.12 OQS07365.1 - 1.3e-08 34.7 0.2 3.4e-05 23.6 0.0 3.4 3 1 0 3 3 3 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 OQS07365.1 - 5e-08 33.0 0.7 0.017 15.1 0.0 3.9 4 1 0 4 4 3 2 AAA domain (dynein-related subfamily) AAA_lid_3 PF17862.1 OQS07365.1 - 6.1e-08 32.4 1.5 0.00057 19.6 0.6 2.8 2 1 0 2 2 2 2 AAA+ lid domain AAA_7 PF12775.7 OQS07365.1 - 1.9e-06 27.5 0.0 0.035 13.6 0.0 2.4 2 0 0 2 2 2 2 P-loop containing dynein motor region IstB_IS21 PF01695.17 OQS07365.1 - 2.2e-06 27.5 0.0 0.0014 18.4 0.0 2.4 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_18 PF13238.6 OQS07365.1 - 7.3e-06 26.6 0.0 0.00031 21.3 0.0 2.6 2 0 0 2 2 2 1 AAA domain Vps4_C PF09336.10 OQS07365.1 - 9.8e-06 25.5 0.3 0.00083 19.3 0.0 2.6 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain TsaE PF02367.17 OQS07365.1 - 3e-05 24.0 0.1 0.0092 16.0 0.0 2.4 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_22 PF13401.6 OQS07365.1 - 5.2e-05 23.5 0.1 0.0095 16.2 0.1 3.4 2 1 1 3 3 3 1 AAA domain TIP49 PF06068.13 OQS07365.1 - 6.2e-05 22.4 0.1 0.0045 16.2 0.0 2.2 2 0 0 2 2 2 1 TIP49 P-loop domain DUF815 PF05673.13 OQS07365.1 - 0.00011 21.5 0.0 0.079 12.1 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF815) Mg_chelatase PF01078.21 OQS07365.1 - 0.00071 19.0 0.2 0.021 14.2 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI T2SSE PF00437.20 OQS07365.1 - 0.00089 18.4 1.0 0.25 10.4 0.0 2.6 3 0 0 3 3 3 1 Type II/IV secretion system protein RNA_helicase PF00910.22 OQS07365.1 - 0.0012 19.2 0.0 0.025 15.0 0.0 2.4 2 0 0 2 2 2 1 RNA helicase AAA_2 PF07724.14 OQS07365.1 - 0.0013 18.8 0.0 0.027 14.6 0.0 2.3 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) Sigma54_activat PF00158.26 OQS07365.1 - 0.0021 17.8 0.0 0.23 11.1 0.0 3.1 4 0 0 4 4 3 1 Sigma-54 interaction domain AAA_33 PF13671.6 OQS07365.1 - 0.0037 17.4 0.0 0.084 13.0 0.0 2.7 2 1 0 2 2 2 1 AAA domain ATPase PF06745.13 OQS07365.1 - 0.0038 16.6 0.0 0.012 15.0 0.0 1.8 1 0 0 1 1 1 1 KaiC AAA_24 PF13479.6 OQS07365.1 - 0.005 16.6 0.2 0.13 12.0 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_3 PF07726.11 OQS07365.1 - 0.0055 16.6 0.1 0.25 11.2 0.0 3.1 4 0 0 4 4 2 1 ATPase family associated with various cellular activities (AAA) Parvo_NS1 PF01057.17 OQS07365.1 - 0.0068 15.5 0.0 0.014 14.5 0.0 1.4 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 NACHT PF05729.12 OQS07365.1 - 0.0095 15.9 0.0 0.57 10.1 0.0 3.3 3 0 0 3 3 3 1 NACHT domain AAA_14 PF13173.6 OQS07365.1 - 0.024 14.7 0.0 0.087 12.9 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 OQS07365.1 - 0.028 14.0 0.1 0.18 11.4 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 OQS07365.1 - 0.031 14.5 0.0 0.077 13.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 OQS07365.1 - 0.04 14.4 0.0 0.11 13.0 0.0 1.7 1 0 0 1 1 1 0 ABC transporter AAA_6 PF12774.7 OQS07365.1 - 0.063 12.2 0.0 9.1 5.1 0.0 3.0 3 0 0 3 3 3 0 Hydrolytic ATP binding site of dynein motor region PhoH PF02562.16 OQS07365.1 - 0.066 12.7 0.0 0.21 11.0 0.0 1.8 2 0 0 2 2 2 0 PhoH-like protein NTPase_1 PF03266.15 OQS07365.1 - 0.08 12.8 0.0 2.4 8.0 0.0 2.8 3 0 0 3 3 2 0 NTPase Rad17 PF03215.15 OQS07365.1 - 0.09 12.7 0.0 11 5.9 0.0 2.7 3 0 0 3 3 2 0 Rad17 P-loop domain AAA_11 PF13086.6 OQS07365.1 - 0.094 12.5 0.0 0.35 10.6 0.0 1.8 2 0 0 2 2 2 0 AAA domain DUF2075 PF09848.9 OQS07365.1 - 0.11 11.7 0.0 0.16 11.1 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_19 PF13245.6 OQS07365.1 - 0.11 12.8 0.8 2.2 8.6 0.0 2.7 3 1 0 3 3 2 0 AAA domain Sigma54_activ_2 PF14532.6 OQS07365.1 - 0.12 12.5 0.0 1.2 9.3 0.0 2.7 3 1 0 3 3 3 0 Sigma-54 interaction domain AAA_29 PF13555.6 OQS07365.1 - 0.13 12.1 0.9 17 5.3 0.1 2.4 2 0 0 2 2 2 0 P-loop containing region of AAA domain NB-ARC PF00931.22 OQS07365.1 - 0.17 11.1 0.0 1 8.5 0.0 2.1 2 0 0 2 2 2 0 NB-ARC domain CHASE3 PF05227.13 OQS07365.1 - 0.34 10.8 1.6 0.74 9.7 1.6 1.5 1 0 0 1 1 1 0 CHASE3 domain Peptidase_S28 PF05577.12 OQS07366.1 - 1.8e-110 369.8 0.1 2.1e-110 369.5 0.1 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase S28 Peptidase_S37 PF05576.11 OQS07366.1 - 0.0008 18.2 0.1 0.0015 17.3 0.1 1.4 1 0 0 1 1 1 1 PS-10 peptidase S37 Abhydrolase_1 PF00561.20 OQS07366.1 - 0.0057 16.3 0.4 0.011 15.4 0.2 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold SWIM PF04434.17 OQS07367.1 - 9.3e-07 28.4 0.2 2.1e-06 27.3 0.2 1.6 1 0 0 1 1 1 1 SWIM zinc finger DBD_Tnp_Mut PF03108.15 OQS07367.1 - 0.00015 21.7 0.2 0.00035 20.5 0.1 1.7 1 1 0 1 1 1 1 MuDR family transposase MULE PF10551.9 OQS07367.1 - 0.0014 19.0 0.0 0.0041 17.5 0.0 1.8 1 0 0 1 1 1 1 MULE transposase domain Thiolase_N PF00108.23 OQS07368.1 - 3e-84 282.5 0.2 6.8e-84 281.3 0.1 1.7 2 0 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 OQS07368.1 - 7.9e-49 164.4 2.4 9.2e-49 164.2 0.6 2.1 3 0 0 3 3 3 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 OQS07368.1 - 0.00042 20.0 0.3 0.00042 20.0 0.3 2.4 3 1 1 4 4 4 1 Beta-ketoacyl synthase, N-terminal domain Pkinase_Tyr PF07714.17 OQS07369.1 - 2.3e-130 433.5 0.0 1.2e-42 146.0 0.0 4.7 5 0 0 5 5 5 4 Protein tyrosine kinase Pkinase PF00069.25 OQS07369.1 - 1.8e-124 414.3 0.0 2.4e-45 154.9 0.0 4.6 4 1 0 5 5 5 4 Protein kinase domain Pkinase_fungal PF17667.1 OQS07369.1 - 1.1e-08 34.3 0.6 0.037 12.8 0.0 3.2 3 0 0 3 3 3 3 Fungal protein kinase Kdo PF06293.14 OQS07369.1 - 1.2e-07 31.3 6.3 0.21 10.9 0.0 4.3 4 0 0 4 4 4 3 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 OQS07369.1 - 5.7e-07 29.1 0.0 0.056 12.7 0.0 4.4 5 0 0 5 5 5 2 Kinase-like RIO1 PF01163.22 OQS07369.1 - 0.00024 20.8 2.4 0.036 13.7 0.0 3.0 3 0 0 3 3 3 2 RIO1 family Guanylate_cyc PF00211.20 OQS07370.1 - 1.1e-28 100.1 0.0 1.9e-08 34.2 0.0 3.3 3 0 0 3 3 3 3 Adenylate and Guanylate cyclase catalytic domain TMCCDC2 PF15844.5 OQS07370.1 - 0.033 14.1 4.3 0.089 12.7 0.3 3.8 2 0 0 2 2 2 0 Transmembrane and coiled-coil domain-containing protein 2 Mito_carr PF00153.27 OQS07371.1 - 2.5e-62 206.8 3.2 2.8e-21 75.2 0.0 3.4 3 0 0 3 3 3 3 Mitochondrial carrier protein Tim17 PF02466.19 OQS07371.1 - 0.01 16.2 0.4 0.01 16.2 0.4 3.6 3 2 0 3 3 3 0 Tim17/Tim22/Tim23/Pmp24 family DUF1358 PF07096.11 OQS07371.1 - 0.048 13.7 0.1 0.2 11.6 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1358) RAP1 PF07218.11 OQS07371.1 - 0.09 11.0 0.0 0.16 10.2 0.0 1.3 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Pkinase PF00069.25 OQS07372.1 - 4.2e-36 124.7 0.0 5.5e-36 124.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQS07372.1 - 1.8e-34 119.2 0.0 2.2e-34 118.9 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OQS07372.1 - 0.0016 17.8 0.0 0.0023 17.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.22 OQS07372.1 - 0.019 14.6 0.1 0.033 13.8 0.1 1.5 1 0 0 1 1 1 0 RIO1 family FTA2 PF13095.6 OQS07372.1 - 0.048 13.3 0.1 1 9.0 0.0 2.2 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 OQS07372.1 - 0.055 12.8 0.3 0.078 12.3 0.3 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Ank_2 PF12796.7 OQS07373.1 - 4.3e-27 94.5 0.1 5.4e-12 46.1 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQS07373.1 - 4.5e-27 94.1 0.6 5.1e-12 46.1 0.3 4.5 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 OQS07373.1 - 1.7e-21 75.9 0.2 0.00015 22.0 0.0 5.2 3 2 2 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQS07373.1 - 1.5e-18 64.9 0.7 0.0014 18.9 0.0 5.6 5 0 0 5 5 5 3 Ankyrin repeat zf-C3HC4_3 PF13920.6 OQS07373.1 - 9.9e-14 50.9 9.9 9.9e-14 50.9 9.9 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Ank PF00023.30 OQS07373.1 - 4.9e-13 48.9 1.2 0.0066 16.8 0.0 4.8 4 0 0 4 4 4 3 Ankyrin repeat zf-RING_2 PF13639.6 OQS07373.1 - 5.4e-05 23.4 10.3 0.00016 21.9 10.3 1.9 1 0 0 1 1 1 1 Ring finger domain Prok-RING_4 PF14447.6 OQS07373.1 - 0.00031 20.5 10.1 0.00075 19.3 10.1 1.7 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 OQS07373.1 - 0.00044 20.0 11.4 0.0013 18.6 11.4 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 OQS07373.1 - 0.001 18.9 10.1 0.0026 17.6 10.1 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) PH PF00169.29 OQS07373.1 - 0.0014 19.1 0.1 0.049 14.2 0.0 2.7 2 0 0 2 2 2 1 PH domain zf-RING_5 PF14634.6 OQS07373.1 - 0.0016 18.3 12.9 0.0022 17.9 10.0 2.5 2 0 0 2 2 2 1 zinc-RING finger domain Acp26Ab PF05777.12 OQS07373.1 - 0.0094 16.6 0.3 0.043 14.5 0.0 2.3 2 0 0 2 2 2 1 Drosophila accessory gland-specific peptide 26Ab (Acp26Ab) zf-RING_4 PF14570.6 OQS07373.1 - 0.096 12.5 8.5 0.23 11.3 8.5 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.6 OQS07373.1 - 1.9 8.7 10.6 6.8 6.9 10.6 2.1 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Ank_2 PF12796.7 OQS07374.1 - 1.3e-98 323.7 23.7 1.5e-18 67.1 0.6 7.7 2 1 5 7 7 7 7 Ankyrin repeats (3 copies) Ank PF00023.30 OQS07374.1 - 2.7e-83 271.1 54.9 2.6e-07 30.8 0.3 16.0 15 1 1 16 16 16 15 Ankyrin repeat Ank_4 PF13637.6 OQS07374.1 - 5.8e-70 230.8 12.6 2.2e-08 34.4 0.0 10.5 5 3 6 11 11 11 11 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQS07374.1 - 1.4e-64 206.3 19.8 0.00026 21.2 0.0 16.1 16 0 0 16 16 16 15 Ankyrin repeat Ank_5 PF13857.6 OQS07374.1 - 1.1e-35 121.2 21.1 4.1e-07 30.1 0.1 11.1 3 2 11 14 14 14 13 Ankyrin repeats (many copies) YfmQ PF10787.9 OQS07374.1 - 4e-06 26.7 0.0 10 5.9 0.0 7.4 4 3 4 9 9 9 1 Uncharacterised protein from bacillus cereus group DUF4226 PF10774.9 OQS07374.1 - 0.0056 17.0 2.7 0.032 14.5 0.9 2.9 3 0 0 3 3 3 1 Domain of unknown function (DUF4226) 3HCDH_RFF PF18321.1 OQS07374.1 - 0.11 12.9 6.9 0.93 10.0 0.0 4.9 5 0 0 5 5 5 0 3-hydroxybutyryl-CoA dehydrogenase reduced Rossmann-fold domain Imm_superinfect PF14373.6 OQS07374.1 - 0.14 12.1 5.3 18 5.3 0.0 5.4 9 0 0 9 9 9 0 Superinfection immunity protein CUE PF02845.16 OQS07374.1 - 2 8.2 10.2 1.2e+02 2.6 0.0 7.0 10 0 0 10 10 10 0 CUE domain BAH PF01426.18 OQS07375.1 - 7.3e-15 54.9 0.0 1.3e-14 54.1 0.0 1.3 1 0 0 1 1 1 1 BAH domain Pkinase_C PF00433.24 OQS07376.1 - 1e-06 29.4 4.2 2.4e-06 28.1 4.2 1.7 1 0 0 1 1 1 1 Protein kinase C terminal domain Ank_2 PF12796.7 OQS07377.1 - 1.7e-18 67.0 0.1 5.2e-13 49.4 0.0 2.0 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) zf-C3HC4_3 PF13920.6 OQS07377.1 - 2.6e-13 49.6 11.5 2.6e-13 49.6 11.5 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Ank_5 PF13857.6 OQS07377.1 - 1.2e-12 47.7 0.5 1.8e-07 31.3 0.3 2.7 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 OQS07377.1 - 1.8e-11 44.3 0.6 1e-10 41.9 0.0 2.3 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.30 OQS07377.1 - 1.4e-09 37.9 3.7 3.6e-05 24.0 0.1 4.3 5 0 0 5 5 5 2 Ankyrin repeat Ank_3 PF13606.6 OQS07377.1 - 3.6e-09 36.1 1.7 4.1e-05 23.6 0.1 3.3 3 0 0 3 3 3 2 Ankyrin repeat zf-RING_2 PF13639.6 OQS07377.1 - 0.00016 22.0 12.1 0.00016 22.0 12.1 2.1 2 0 0 2 2 2 1 Ring finger domain Prok-RING_4 PF14447.6 OQS07377.1 - 0.0025 17.6 11.2 0.0025 17.6 11.2 1.8 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 OQS07377.1 - 0.0042 16.9 12.8 0.0099 15.7 12.8 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 OQS07377.1 - 0.06 13.2 8.5 0.19 11.6 8.5 1.8 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.6 OQS07377.1 - 0.18 12.0 11.7 0.7 10.1 11.7 2.1 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Sfi1 PF08457.10 OQS07377.1 - 0.27 9.7 0.9 0.38 9.2 0.9 1.2 1 0 0 1 1 1 0 Sfi1 spindle body protein zf-RING_5 PF14634.6 OQS07377.1 - 1.8 8.6 18.4 0.088 12.8 11.0 2.4 2 0 0 2 2 2 0 zinc-RING finger domain AAA_11 PF13086.6 OQS07379.1 - 8e-64 215.9 1.7 8e-64 215.9 1.7 3.1 2 1 0 2 2 1 1 AAA domain AAA_12 PF13087.6 OQS07379.1 - 2.7e-55 187.1 9.0 1.6e-54 184.5 0.1 2.9 3 0 0 3 3 3 2 AAA domain AAA_30 PF13604.6 OQS07379.1 - 1.4e-13 51.0 0.1 5.7e-12 45.8 0.1 2.8 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 OQS07379.1 - 2.7e-09 37.5 2.5 5e-09 36.7 0.3 2.6 3 1 0 3 3 3 1 AAA domain zf-AN1 PF01428.16 OQS07379.1 - 4.2e-08 33.2 5.8 8.3e-08 32.3 5.8 1.5 1 0 0 1 1 1 1 AN1-like Zinc finger ResIII PF04851.15 OQS07379.1 - 6e-08 32.9 0.2 6.4e-07 29.5 0.0 2.8 3 1 0 3 3 2 1 Type III restriction enzyme, res subunit Viral_helicase1 PF01443.18 OQS07379.1 - 9.7e-08 32.0 3.3 0.17 11.6 0.1 4.0 3 1 1 4 4 4 3 Viral (Superfamily 1) RNA helicase Helicase_RecD PF05127.14 OQS07379.1 - 2.2e-05 24.4 6.6 6.7e-05 22.8 0.4 3.6 3 1 0 3 3 2 1 Helicase PhoH PF02562.16 OQS07379.1 - 0.00053 19.5 0.3 0.0025 17.3 0.3 2.1 1 1 0 1 1 1 1 PhoH-like protein AAA PF00004.29 OQS07379.1 - 0.00077 19.9 0.5 0.0033 17.9 0.5 2.2 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) T2SSE PF00437.20 OQS07379.1 - 0.001 18.2 0.0 0.0027 16.8 0.0 1.7 1 0 0 1 1 1 1 Type II/IV secretion system protein Flavi_DEAD PF07652.14 OQS07379.1 - 0.0024 17.9 0.2 0.0024 17.9 0.2 2.5 3 1 0 3 3 1 1 Flavivirus DEAD domain DEAD PF00270.29 OQS07379.1 - 0.0026 17.6 0.2 0.0026 17.6 0.2 3.1 2 1 0 3 3 3 1 DEAD/DEAH box helicase AAA_22 PF13401.6 OQS07379.1 - 0.0028 17.9 0.1 0.023 15.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 OQS07379.1 - 0.0038 16.8 0.0 0.022 14.3 0.0 2.3 2 0 0 2 2 2 1 AAA domain UvrD-helicase PF00580.21 OQS07379.1 - 0.0044 16.6 0.0 0.0044 16.6 0.0 3.1 2 2 0 2 2 1 1 UvrD/REP helicase N-terminal domain DUF2075 PF09848.9 OQS07379.1 - 0.0062 15.8 9.4 0.025 13.8 2.6 3.7 2 1 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) AAA_16 PF13191.6 OQS07379.1 - 0.0082 16.5 0.0 0.032 14.6 0.0 2.1 1 0 0 1 1 1 1 AAA ATPase domain Rad17 PF03215.15 OQS07379.1 - 0.028 14.4 0.1 0.1 12.5 0.1 2.0 2 0 0 2 2 1 0 Rad17 P-loop domain SRP54 PF00448.22 OQS07379.1 - 0.056 13.1 1.8 0.2 11.2 0.1 2.9 3 1 1 4 4 3 0 SRP54-type protein, GTPase domain AAA_7 PF12775.7 OQS07379.1 - 0.082 12.4 0.0 0.26 10.8 0.0 1.8 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_18 PF13238.6 OQS07379.1 - 0.09 13.3 0.0 0.62 10.6 0.0 2.5 1 0 0 1 1 1 0 AAA domain Glycos_transf_2 PF00535.26 OQS07379.1 - 0.092 12.6 0.0 0.26 11.1 0.0 1.7 1 0 0 1 1 1 0 Glycosyl transferase family 2 AAA_14 PF13173.6 OQS07379.1 - 0.12 12.4 0.1 5.4 7.1 0.0 3.0 2 1 0 2 2 2 0 AAA domain ATPase_2 PF01637.18 OQS07379.1 - 0.12 12.2 2.8 0.14 12.0 0.0 2.6 2 1 0 2 2 2 0 ATPase domain predominantly from Archaea AAA_33 PF13671.6 OQS07379.1 - 0.18 11.9 2.4 0.2 11.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain DUF2203 PF09969.9 OQS07379.1 - 8.6 7.1 6.9 8.5 7.1 0.2 3.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) Peptidase_M16_M PF16187.5 OQS07380.1 - 1.8e-66 224.3 1.4 2.6e-66 223.8 1.4 1.3 1 0 0 1 1 1 1 Middle or third domain of peptidase_M16 Peptidase_M16 PF00675.20 OQS07380.1 - 6.4e-32 110.6 2.2 5.4e-31 107.6 0.0 3.2 4 0 0 4 4 3 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 OQS07380.1 - 1.8e-29 103.0 0.0 1.2e-17 64.6 0.0 3.4 3 1 1 4 4 4 2 Peptidase M16 inactive domain SDA1 PF05285.12 OQS07380.1 - 0.0058 16.1 7.8 0.0084 15.6 7.8 1.1 1 0 0 1 1 1 1 SDA1 BUD22 PF09073.10 OQS07380.1 - 0.022 14.1 5.1 0.033 13.5 5.1 1.2 1 0 0 1 1 1 0 BUD22 Prothymosin PF03247.14 OQS07380.1 - 0.027 14.9 18.9 0.055 13.9 18.9 1.4 1 0 0 1 1 1 0 Prothymosin/parathymosin family FAM176 PF14851.6 OQS07380.1 - 0.058 13.1 2.7 0.15 11.7 2.7 1.6 1 0 0 1 1 1 0 FAM176 family Nop14 PF04147.12 OQS07380.1 - 0.74 8.0 14.8 1.3 7.2 14.8 1.2 1 0 0 1 1 1 0 Nop14-like family TRAP_alpha PF03896.16 OQS07380.1 - 1.7 7.8 7.2 3 7.0 7.2 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit RXT2_N PF08595.11 OQS07380.1 - 2 8.4 9.5 4.5 7.3 9.5 1.5 1 0 0 1 1 1 0 RXT2-like, N-terminal Pox_Ag35 PF03286.14 OQS07380.1 - 4.5 7.0 7.4 8.8 6.1 7.4 1.4 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Cwf_Cwc_15 PF04889.12 OQS07380.1 - 4.6 6.9 14.6 7.9 6.1 14.6 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein NOA36 PF06524.12 OQS07380.1 - 8.1 5.7 17.6 13 5.0 17.6 1.2 1 0 0 1 1 1 0 NOA36 protein TFB6 PF17110.5 OQS07380.1 - 8.4 6.1 6.8 24 4.6 6.8 1.7 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH Paf1 PF03985.13 OQS07380.1 - 8.4 5.3 12.3 14 4.5 12.3 1.3 1 0 0 1 1 1 0 Paf1 E2F_CC-MB PF16421.5 OQS07382.1 - 8.7e-27 93.3 0.0 1.5e-26 92.5 0.0 1.4 1 0 0 1 1 1 1 E2F transcription factor CC-MB domain E2F_TDP PF02319.20 OQS07382.1 - 2.3e-24 85.3 0.0 4e-24 84.5 0.0 1.4 1 0 0 1 1 1 1 E2F/DP family winged-helix DNA-binding domain TrmB PF01978.19 OQS07382.1 - 0.032 14.1 0.0 0.067 13.1 0.0 1.5 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB B-block_TFIIIC PF04182.12 OQS07382.1 - 0.091 12.9 0.0 0.21 11.7 0.0 1.6 1 0 0 1 1 1 0 B-block binding subunit of TFIIIC HTH_47 PF16221.5 OQS07382.1 - 0.18 11.4 0.0 0.41 10.2 0.0 1.6 1 0 0 1 1 1 0 winged helix-turn-helix EF-hand_1 PF00036.32 OQS07383.1 - 9.1e-10 37.4 0.1 0.00057 19.2 0.0 2.8 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 OQS07383.1 - 3.1e-09 37.1 0.2 1.2e-08 35.3 0.0 2.1 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 OQS07383.1 - 1.4e-07 30.9 0.0 0.00092 19.0 0.0 2.9 2 0 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.6 OQS07383.1 - 0.0022 17.8 0.4 1.5 8.7 0.1 3.3 3 0 0 3 3 3 2 EF-hand domain pair FUSC PF04632.12 OQS07383.1 - 0.031 12.8 5.2 0.0057 15.3 0.9 1.9 2 0 0 2 2 2 0 Fusaric acid resistance protein family FixQ PF05545.11 OQS07383.1 - 5.4 7.1 9.2 9.5 6.3 0.1 3.8 3 0 0 3 3 3 0 Cbb3-type cytochrome oxidase component FixQ Carbam_trans_N PF02543.15 OQS07384.1 - 0.0056 16.4 0.7 0.02 14.6 0.1 2.1 2 0 0 2 2 2 1 Carbamoyltransferase N-terminus ASF1_hist_chap PF04729.13 OQS07385.1 - 0.0041 17.1 0.0 0.0053 16.7 0.0 1.2 1 0 0 1 1 1 1 ASF1 like histone chaperone E1_DerP2_DerF2 PF02221.15 OQS07385.1 - 0.089 13.2 0.0 0.11 12.9 0.0 1.2 1 0 0 1 1 1 0 ML domain BBL5 PF07289.11 OQS07386.1 - 1.6e-148 494.2 0.4 2.6e-148 493.5 0.4 1.3 1 0 0 1 1 1 1 Bardet-Biedl syndrome 5 protein Ank_2 PF12796.7 OQS07386.1 - 2.1e-17 63.5 1.9 0.0068 17.0 0.0 6.6 4 2 1 6 6 6 4 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OQS07386.1 - 3.7e-12 46.2 4.6 1 9.8 0.0 8.0 8 0 0 8 8 8 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQS07386.1 - 2.5e-10 39.7 12.3 0.77 10.5 0.0 10.3 10 0 0 10 10 10 2 Ankyrin repeat DUF4598 PF15370.6 OQS07386.1 - 3.9e-08 33.7 2.0 6.3e-08 33.1 0.6 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4598) Ank_4 PF13637.6 OQS07386.1 - 1.3e-07 32.0 5.4 0.14 12.8 0.1 7.8 6 2 2 8 8 8 2 Ankyrin repeats (many copies) Ion_trans PF00520.31 OQS07386.1 - 2.1e-05 23.9 39.3 0.013 14.8 10.3 2.7 2 0 0 2 2 2 2 Ion transport protein PH_TFIIH PF08567.11 OQS07386.1 - 0.00027 21.2 0.0 0.17 12.2 0.0 2.8 2 0 0 2 2 2 1 TFIIH p62 subunit, N-terminal domain bPH_3 PF14470.6 OQS07386.1 - 0.049 14.0 0.0 0.2 12.1 0.0 2.0 1 0 0 1 1 1 0 Bacterial PH domain Ank PF00023.30 OQS07386.1 - 0.091 13.3 11.6 61 4.3 0.0 7.2 8 0 0 8 8 8 0 Ankyrin repeat DUF2985 PF11204.8 OQS07386.1 - 1.6 9.0 8.0 14 5.9 1.7 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2985) DUF2458 PF10454.9 OQS07386.1 - 1.6 8.3 5.4 0.83 9.3 2.4 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2458) DUF3278 PF11683.8 OQS07386.1 - 1.7 8.7 22.4 1.6 8.8 0.7 4.7 4 0 0 4 4 4 0 Protein of unknown function (DUF3278) BCIP PF13862.6 OQS07387.1 - 8.3e-47 159.6 0.0 1.1e-46 159.2 0.0 1.2 1 0 0 1 1 1 1 p21-C-terminal region-binding protein HAS-barrel PF09378.10 OQS07387.1 - 0.084 13.0 0.0 0.2 11.8 0.0 1.7 1 0 0 1 1 1 0 HAS barrel domain Peptidase_M1 PF01433.20 OQS07388.1 - 1e-25 90.6 0.5 2.5e-25 89.3 0.2 1.9 2 0 0 2 2 2 1 Peptidase family M1 domain DUF3458_C PF17432.2 OQS07388.1 - 3.9e-19 69.2 6.1 6e-19 68.6 6.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3458_C) ARM repeats Peptidase_M1_N PF17900.1 OQS07388.1 - 4.9e-12 46.4 0.6 1e-11 45.4 0.1 1.7 2 0 0 2 2 2 1 Peptidase M1 N-terminal domain DUF3458 PF11940.8 OQS07388.1 - 7e-09 36.0 0.0 1.1e-07 32.2 0.0 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF3458) Ig-like fold Cas_Cas4 PF01930.17 OQS07388.1 - 0.035 14.2 0.1 0.1 12.7 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function DUF83 AAA_16 PF13191.6 OQS07388.1 - 0.068 13.6 0.3 2.1 8.7 0.2 2.6 1 1 0 1 1 1 0 AAA ATPase domain RabGAP-TBC PF00566.18 OQS07389.1 - 9.9e-36 123.4 2.2 1.9e-35 122.5 2.2 1.5 1 0 0 1 1 1 1 Rab-GTPase-TBC domain fn3 PF00041.21 OQS07389.1 - 2.6e-19 69.3 0.5 7e-13 48.7 0.0 3.0 2 0 0 2 2 2 2 Fibronectin type III domain Pur_ac_phosph_N PF16656.5 OQS07389.1 - 4.3e-06 27.2 7.4 0.0028 18.2 0.1 3.9 4 0 0 4 4 4 2 Purple acid Phosphatase, N-terminal domain PDZ PF00595.24 OQS07389.1 - 2.4e-05 24.6 0.0 7e-05 23.1 0.0 1.7 1 0 0 1 1 1 1 PDZ domain CDC27 PF09507.10 OQS07389.1 - 2.6e-05 23.8 36.3 5.4e-05 22.8 36.3 1.5 1 0 0 1 1 1 1 DNA polymerase subunit Cdc27 PDZ_6 PF17820.1 OQS07389.1 - 0.00097 18.9 0.0 0.0024 17.7 0.0 1.8 1 0 0 1 1 1 1 PDZ domain Pro_isomerase PF00160.21 OQS07391.1 - 3.4e-53 180.1 0.0 4e-53 179.9 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DUF3830 PF12903.7 OQS07391.1 - 0.065 12.9 0.0 0.28 10.8 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3830) DUF1279 PF06916.13 OQS07392.1 - 2.2e-13 50.6 1.1 7e-13 49.0 1.1 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF1279) TPR_12 PF13424.6 OQS07393.1 - 1.3e-13 51.1 0.1 1.1e-11 44.9 0.0 2.7 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.17 OQS07393.1 - 1.2e-05 25.1 0.0 0.32 11.2 0.0 3.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 OQS07393.1 - 1.2e-05 24.9 1.3 0.05 13.5 0.0 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_10 PF13374.6 OQS07393.1 - 0.007 16.2 0.1 8.4 6.4 0.0 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat DUF2205 PF10224.9 OQS07393.1 - 0.025 14.6 0.8 20 5.2 0.1 3.6 3 0 0 3 3 3 0 Short coiled-coil protein TPR_8 PF13181.6 OQS07393.1 - 0.053 13.8 0.2 4.3 7.8 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat zinc_ribbon_2 PF13240.6 OQS07394.1 - 0.0025 17.5 1.3 0.0049 16.5 1.3 1.5 1 0 0 1 1 1 1 zinc-ribbon domain DUF1308 PF07000.11 OQS07394.1 - 0.013 15.4 1.7 0.017 15.1 1.7 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1308) zf-RanBP PF00641.18 OQS07394.1 - 0.024 14.0 2.9 0.044 13.1 2.9 1.4 1 0 0 1 1 1 0 Zn-finger in Ran binding protein and others Ureide_permease PF07168.11 OQS07394.1 - 0.35 9.6 13.2 0.44 9.2 13.2 1.1 1 0 0 1 1 1 0 Ureide permease CDC27 PF09507.10 OQS07394.1 - 0.45 9.9 21.6 0.49 9.7 21.6 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 DDRGK PF09756.9 OQS07394.1 - 1.5 8.4 26.7 1.8 8.1 26.7 1.1 1 0 0 1 1 1 0 DDRGK domain OATP PF03137.20 OQS07394.1 - 1.5 7.0 7.4 1.7 6.8 7.4 1.2 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family DUF2058 PF09831.9 OQS07394.1 - 1.5 8.9 17.6 2 8.6 17.6 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2058) Sporozoite_P67 PF05642.11 OQS07394.1 - 1.6 6.7 8.1 1.6 6.7 8.1 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen PPL5 PF18168.1 OQS07394.1 - 1.9 7.7 13.5 2.3 7.5 13.5 1.1 1 0 0 1 1 1 0 Prim-pol family 5 DUF4407 PF14362.6 OQS07394.1 - 2 7.7 10.2 2.4 7.4 10.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Presenilin PF01080.17 OQS07394.1 - 2.1 7.0 15.5 2.1 7.0 15.5 1.0 1 0 0 1 1 1 0 Presenilin Red1 PF07964.11 OQS07394.1 - 3.1 5.9 23.2 3.2 5.9 23.2 1.0 1 0 0 1 1 1 0 Rec10 / Red1 DUF5523 PF17661.1 OQS07394.1 - 3.4 7.3 20.9 4.3 7.0 20.9 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5523) CENP-N PF05238.13 OQS07394.1 - 4 6.6 14.5 5.2 6.3 14.5 1.1 1 0 0 1 1 1 0 Kinetochore protein CHL4 like Peptidase_S64 PF08192.11 OQS07394.1 - 4.4 5.7 11.1 4.6 5.6 11.1 1.0 1 0 0 1 1 1 0 Peptidase family S64 RPN2_C PF18004.1 OQS07394.1 - 5.7 6.8 20.5 7.8 6.4 20.5 1.3 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain ALMT PF11744.8 OQS07394.1 - 8.6 5.1 11.6 9.2 5.0 11.6 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter SQS_PSY PF00494.19 OQS07395.1 - 1.1e-49 169.4 6.2 1.3e-49 169.1 6.2 1.0 1 0 0 1 1 1 1 Squalene/phytoene synthase SoDot-IcmSS PF16848.5 OQS07395.1 - 0.005 16.8 0.0 0.0077 16.2 0.0 1.3 1 0 0 1 1 1 1 Substrate of the Dot/Icm secretion system, putative BrnA_antitoxin PF14384.6 OQS07396.1 - 0.19 12.3 1.8 0.31 11.6 0.6 1.9 2 0 0 2 2 2 0 BrnA antitoxin of type II toxin-antitoxin system SPT6_acidic PF14632.6 OQS07396.1 - 0.58 10.8 5.6 1.2 9.7 5.6 1.5 1 0 0 1 1 1 0 Acidic N-terminal SPT6 PDEase_I PF00233.19 OQS07397.1 - 8.9e-58 195.8 0.2 2.6e-57 194.3 0.2 1.8 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase Guanylate_cyc PF00211.20 OQS07397.1 - 4.6e-11 42.7 0.0 2.5e-10 40.3 0.0 2.1 1 1 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Ion_trans PF00520.31 OQS07397.1 - 0.00066 19.0 6.4 0.00066 19.0 6.4 1.8 2 0 0 2 2 2 1 Ion transport protein HD PF01966.22 OQS07397.1 - 0.016 15.4 0.0 0.05 13.8 0.0 1.8 1 0 0 1 1 1 0 HD domain EAV_GP5 PF15981.5 OQS07397.1 - 0.049 14.0 0.3 0.28 11.6 0.0 2.4 3 0 0 3 3 3 0 Envelope glycoprotein GP 5 of equine arteritis virus LapA_dom PF06305.11 OQS07398.1 - 0.072 12.9 0.4 0.13 12.1 0.1 1.6 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain EamA PF00892.20 OQS07399.1 - 1.2e-11 44.9 26.6 1.1e-06 28.9 13.2 2.3 2 0 0 2 2 2 2 EamA-like transporter family DUF3923 PF13061.6 OQS07399.1 - 0.054 13.6 1.4 13 6.0 0.4 3.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3923) Saf_2TM PF18303.1 OQS07399.1 - 5.4 6.6 5.4 6.3 6.4 0.1 2.8 3 0 0 3 3 3 0 SAVED-fused 2TM effector domain Methyltransf_25 PF13649.6 OQS07400.1 - 1.4e-09 38.5 0.0 2.1e-09 38.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OQS07400.1 - 1.9e-09 37.5 0.0 2.5e-09 37.1 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OQS07400.1 - 1.6e-08 34.6 0.0 2.1e-08 34.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OQS07400.1 - 7.8e-08 33.0 0.0 1.2e-07 32.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OQS07400.1 - 3.2e-07 30.9 0.0 5.5e-07 30.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MetW PF07021.12 OQS07400.1 - 1.1e-05 25.1 0.4 1.7e-05 24.5 0.4 1.6 1 1 0 1 1 1 1 Methionine biosynthesis protein MetW PCMT PF01135.19 OQS07400.1 - 0.00013 21.8 0.0 0.00016 21.5 0.0 1.1 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MTS PF05175.14 OQS07400.1 - 0.00027 20.5 0.0 0.00044 19.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Ubie_methyltran PF01209.18 OQS07400.1 - 0.001 18.5 0.1 0.0012 18.2 0.1 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family PrmA PF06325.13 OQS07400.1 - 0.027 13.9 0.0 0.033 13.6 0.0 1.1 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) DUF547 PF04784.14 OQS07402.1 - 2.7e-13 50.1 0.1 5.7e-13 49.0 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function, DUF547 MORN PF02493.20 OQS07403.1 - 2.4e-29 99.4 60.4 0.00014 21.5 0.4 9.5 9 0 0 9 9 9 8 MORN repeat Ins145_P3_rec PF08709.11 OQS07403.1 - 7.8e-24 84.1 0.1 4.6e-22 78.3 0.0 3.2 1 1 2 3 3 3 1 Inositol 1,4,5-trisphosphate/ryanodine receptor RIH_assoc PF08454.11 OQS07403.1 - 2.1e-21 75.7 1.7 2.1e-21 75.7 1.7 3.7 2 0 0 2 2 2 1 RyR and IP3R Homology associated Ion_trans PF00520.31 OQS07403.1 - 2.4e-10 40.1 3.4 6.1e-10 38.8 3.4 1.7 1 0 0 1 1 1 1 Ion transport protein MIR PF02815.19 OQS07403.1 - 2.5e-09 37.3 2.2 3.2e-05 23.9 0.2 4.0 1 1 1 3 3 3 3 MIR domain RYDR_ITPR PF01365.21 OQS07403.1 - 9.4e-06 25.2 0.0 9.4e-06 25.2 0.0 3.9 4 1 0 4 4 4 1 RIH domain ENTH PF01417.20 OQS07403.1 - 0.075 13.1 1.4 0.17 11.9 0.2 2.2 2 0 0 2 2 2 0 ENTH domain Phage_Gp23 PF10669.9 OQS07403.1 - 2.6 8.4 6.7 0.38 11.1 1.6 2.3 2 0 0 2 2 2 0 Protein gp23 (Bacteriophage A118) U-box PF04564.15 OQS07404.1 - 6.7e-24 83.9 0.1 1.3e-23 83.0 0.1 1.5 1 0 0 1 1 1 1 U-box domain TPR_1 PF00515.28 OQS07404.1 - 5e-17 60.9 8.5 8.8e-06 25.3 0.2 3.9 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.17 OQS07404.1 - 1.4e-14 52.9 4.8 0.00037 20.4 0.1 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 OQS07404.1 - 7.4e-14 51.2 5.4 4.8e-07 29.3 0.1 2.8 3 0 0 3 3 3 2 TPR repeat TPR_12 PF13424.6 OQS07404.1 - 3.8e-08 33.5 5.2 8.5e-05 22.8 0.4 2.9 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 OQS07404.1 - 4.3e-08 32.7 8.8 0.0094 16.1 0.4 4.1 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_17 PF13431.6 OQS07404.1 - 1.2e-06 28.5 3.0 0.00017 21.7 0.0 3.5 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.6 OQS07404.1 - 2.2e-05 24.2 0.5 0.13 12.3 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 OQS07404.1 - 3.8e-05 24.3 0.0 0.39 11.4 0.0 2.6 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 OQS07404.1 - 0.00011 22.7 0.3 0.15 13.0 0.0 3.9 2 1 3 5 5 4 2 Tetratricopeptide repeat TPR_19 PF14559.6 OQS07404.1 - 0.00053 20.5 0.6 0.055 14.0 0.3 2.7 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.6 OQS07404.1 - 0.0025 17.9 0.0 0.33 11.1 0.1 3.0 1 1 2 3 3 3 1 Tetratricopeptide repeat ANAPC3 PF12895.7 OQS07404.1 - 0.01 16.0 0.9 0.01 16.0 0.9 2.7 1 1 2 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.6 OQS07404.1 - 0.015 15.2 3.7 23 5.0 0.1 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat MLD PF11647.8 OQS07404.1 - 0.09 13.1 0.3 0.69 10.2 0.1 2.4 2 0 0 2 2 2 0 Membrane Localization Domain TPR_6 PF13174.6 OQS07404.1 - 0.27 11.9 3.3 51 4.8 0.1 3.8 4 0 0 4 4 3 0 Tetratricopeptide repeat Peptidase_M20 PF01546.28 OQS07405.1 - 1.7e-21 76.9 0.0 2.5e-21 76.4 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 OQS07405.1 - 2.6e-08 33.7 0.2 6.8e-08 32.4 0.2 1.7 1 0 0 1 1 1 1 Peptidase dimerisation domain Elicitin PF00964.17 OQS07408.1 - 5.6e-06 26.4 0.3 5.6e-06 26.4 0.3 2.5 2 0 0 2 2 2 1 Elicitin AMP-binding PF00501.28 OQS07410.1 - 1.4e-176 587.3 0.0 3.3e-87 292.8 0.0 2.1 2 0 0 2 2 2 2 AMP-binding enzyme AMP-binding_C PF13193.6 OQS07410.1 - 6.6e-08 33.4 0.5 0.00016 22.6 0.1 2.7 2 0 0 2 2 2 2 AMP-binding enzyme C-terminal domain STIMATE PF12400.8 OQS07411.1 - 1.4e-32 112.9 1.4 1.4e-32 112.9 1.4 1.8 2 0 0 2 2 2 1 STIMATE family TTL PF03133.15 OQS07412.1 - 2.6e-82 276.3 0.0 4.2e-82 275.6 0.0 1.2 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 OQS07412.1 - 3.4e-05 23.2 0.0 0.0012 18.2 0.0 2.7 2 1 0 2 2 2 1 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 OQS07412.1 - 0.01 15.1 0.0 0.17 11.1 0.0 2.1 2 0 0 2 2 2 0 Sugar-transfer associated ATP-grasp ATP-grasp_3 PF02655.14 OQS07412.1 - 0.16 12.0 0.0 5.8 6.9 0.0 2.7 2 1 0 2 2 2 0 ATP-grasp domain Kelch_1 PF01344.25 OQS07413.1 - 2.7e-41 138.9 17.2 6.9e-09 35.2 0.2 6.9 7 0 0 7 7 7 6 Kelch motif Kelch_6 PF13964.6 OQS07413.1 - 4.9e-40 134.5 14.0 2.9e-09 36.9 0.1 7.7 3 1 5 8 8 8 6 Kelch motif Kelch_3 PF13415.6 OQS07413.1 - 1.5e-34 117.6 9.5 2e-07 31.1 0.0 6.8 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_4 PF13418.6 OQS07413.1 - 4.2e-33 113.1 12.7 3.6e-05 23.7 0.0 6.8 5 1 1 6 6 6 6 Galactose oxidase, central domain Kelch_5 PF13854.6 OQS07413.1 - 4.6e-30 103.1 13.0 2.2e-06 27.5 0.2 6.8 6 0 0 6 6 6 6 Kelch motif Kelch_2 PF07646.15 OQS07413.1 - 1.7e-29 100.6 16.8 8.5e-05 22.4 0.2 7.8 8 0 0 8 8 8 6 Kelch motif BTB PF00651.31 OQS07413.1 - 6e-22 78.0 0.3 2.4e-21 76.0 0.1 2.0 1 1 1 2 2 2 1 BTB/POZ domain BACK PF07707.15 OQS07413.1 - 0.00039 20.5 0.3 0.0015 18.6 0.1 2.0 2 0 0 2 2 2 1 BTB And C-terminal Kelch ANAPC4_WD40 PF12894.7 OQS07413.1 - 0.0011 19.2 0.0 1.9 8.8 0.0 4.2 2 1 3 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 OQS07413.1 - 0.022 15.6 8.6 0.099 13.6 0.0 5.5 6 0 0 6 6 5 0 WD domain, G-beta repeat Nbas_N PF15492.6 OQS07413.1 - 0.034 13.5 0.5 1.1 8.5 0.0 3.2 3 1 1 4 4 4 0 Neuroblastoma-amplified sequence, N terminal Methyltransf_28 PF02636.17 OQS07414.1 - 2.4e-71 240.4 0.0 2.7e-70 237.0 0.0 2.4 2 1 0 2 2 2 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Voltage_CLC PF00654.20 OQS07414.1 - 1.3e-48 166.0 29.6 1.3e-48 166.0 29.6 1.8 1 1 1 2 2 2 1 Voltage gated chloride channel CBS PF00571.28 OQS07414.1 - 3.5e-05 24.2 1.3 0.00017 22.0 0.2 2.7 3 0 0 3 3 3 1 CBS domain Mpv17_PMP22 PF04117.12 OQS07415.1 - 2.6e-19 69.2 3.8 4.7e-19 68.4 3.8 1.4 1 0 0 1 1 1 1 Mpv17 / PMP22 family Pkinase PF00069.25 OQS07416.1 - 8e-20 71.3 0.0 4.3e-17 62.3 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQS07416.1 - 1.2e-13 50.9 0.0 1.2e-10 41.1 0.0 2.0 2 0 0 2 2 2 2 Protein tyrosine kinase DUF2027 PF09640.10 OQS07416.1 - 0.079 12.6 0.0 2 8.0 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF2027) Integrin_alpha PF00357.20 OQS07416.1 - 0.13 12.3 0.6 0.28 11.2 0.6 1.6 1 0 0 1 1 1 0 Integrin alpha cytoplasmic region Mito_carr PF00153.27 OQS07417.1 - 6.1e-64 212.0 1.8 2.4e-21 75.4 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF2835 PF11197.8 OQS07417.1 - 0.11 12.4 0.4 6.5 6.7 0.0 3.2 3 1 1 4 4 4 0 Protein of unknown function (DUF2835) SelR PF01641.18 OQS07417.1 - 0.12 12.4 0.1 0.22 11.6 0.1 1.4 1 0 0 1 1 1 0 SelR domain HMMR_N PF15905.5 OQS07419.1 - 0.0017 17.9 16.0 0.0017 17.9 16.0 2.7 1 1 2 3 3 1 1 Hyaluronan mediated motility receptor N-terminal Tropomyosin_1 PF12718.7 OQS07419.1 - 0.0018 18.5 6.4 0.0018 18.5 6.4 4.3 1 1 2 4 4 4 1 Tropomyosin like GAS PF13851.6 OQS07419.1 - 0.0025 17.2 9.6 0.0025 17.2 9.6 3.7 1 1 3 4 4 3 1 Growth-arrest specific micro-tubule binding Spc7 PF08317.11 OQS07419.1 - 0.0043 16.0 9.1 0.0043 16.0 9.1 3.5 2 2 2 4 4 4 1 Spc7 kinetochore protein DUF812 PF05667.11 OQS07419.1 - 0.0061 15.5 8.8 0.0061 15.5 8.8 2.4 1 1 0 2 2 2 1 Protein of unknown function (DUF812) DUF1664 PF07889.12 OQS07419.1 - 0.0077 16.3 29.4 0.052 13.6 4.4 3.9 2 2 1 3 3 3 2 Protein of unknown function (DUF1664) Baculo_PEP_C PF04513.12 OQS07419.1 - 0.011 15.8 0.8 0.011 15.8 0.8 3.7 2 2 3 5 5 5 0 Baculovirus polyhedron envelope protein, PEP, C terminus CENP-F_leu_zip PF10473.9 OQS07419.1 - 0.013 15.5 6.9 0.013 15.5 6.9 4.2 2 2 2 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ATG16 PF08614.11 OQS07419.1 - 0.022 15.0 29.3 0.041 14.1 10.1 3.2 2 2 1 3 3 3 0 Autophagy protein 16 (ATG16) SCO1-SenC PF02630.14 OQS07419.1 - 0.036 14.0 0.5 0.13 12.2 0.3 2.0 1 1 1 2 2 2 0 SCO1/SenC Nup54 PF13874.6 OQS07419.1 - 0.071 13.2 13.3 0.039 14.1 2.7 3.1 2 1 1 3 3 3 0 Nucleoporin complex subunit 54 CP12 PF02672.15 OQS07419.1 - 0.14 12.9 0.5 0.14 12.9 0.5 3.6 3 1 1 4 4 3 0 CP12 domain HrpB7 PF09486.10 OQS07419.1 - 0.23 11.9 22.1 0.031 14.7 4.5 3.6 2 2 0 2 2 2 0 Bacterial type III secretion protein (HrpB7) BLOC1_2 PF10046.9 OQS07419.1 - 0.71 10.2 23.0 0.18 12.1 1.0 4.3 3 2 2 5 5 5 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Vip3A_N PF12495.8 OQS07419.1 - 1.1 9.1 7.9 0.32 10.9 0.6 3.0 2 2 1 3 3 3 0 Vegetative insecticide protein 3A N terminal Bacillus_HBL PF05791.11 OQS07419.1 - 1.2 8.9 22.8 0.038 13.8 2.3 3.7 3 1 1 4 4 4 0 Bacillus haemolytic enterotoxin (HBL) Lebercilin PF15619.6 OQS07419.1 - 1.7 8.2 31.3 0.19 11.4 4.5 4.3 1 1 2 4 4 4 0 Ciliary protein causing Leber congenital amaurosis disease RasGAP_C PF03836.15 OQS07419.1 - 1.9 8.7 14.8 0.22 11.7 2.2 3.1 2 1 1 3 3 3 0 RasGAP C-terminus HAUS-augmin3 PF14932.6 OQS07419.1 - 2.8 7.4 21.8 0.033 13.8 4.7 2.4 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 3 TMPIT PF07851.13 OQS07419.1 - 3.1 7.0 22.8 0.11 11.8 6.6 2.9 2 1 1 3 3 3 0 TMPIT-like protein DUF3450 PF11932.8 OQS07419.1 - 3.2 7.0 23.5 0.015 14.6 4.5 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF3450) Spectrin PF00435.21 OQS07419.1 - 3.9 8.0 23.7 0.56 10.7 5.1 3.8 3 1 1 4 4 4 0 Spectrin repeat ApoO PF09769.9 OQS07419.1 - 6.1 6.8 7.4 10 6.1 0.1 3.7 3 2 0 3 3 2 0 Apolipoprotein O Fzo_mitofusin PF04799.13 OQS07419.1 - 7.7 6.0 19.6 0.16 11.6 1.3 3.9 2 2 2 4 4 4 0 fzo-like conserved region Anti-adapt_IraP PF10796.9 OQS07419.1 - 8 7.1 18.1 1.3 9.6 0.4 4.4 3 2 2 5 5 5 0 Sigma-S stabilisation anti-adaptor protein FlaC_arch PF05377.11 OQS07419.1 - 9.5 6.7 25.1 1.1 9.7 2.5 4.9 4 1 0 5 5 4 0 Flagella accessory protein C (FlaC) ThiF PF00899.21 OQS07420.1 - 4.3e-20 72.1 0.0 7.6e-20 71.3 0.0 1.4 1 0 0 1 1 1 1 ThiF family DUF16 PF01519.16 OQS07420.1 - 0.13 12.8 26.3 0.043 14.3 5.2 4.7 3 2 1 4 4 4 0 Protein of unknown function DUF16 E2R135 PF11570.8 OQS07420.1 - 0.3 11.4 4.6 0.46 10.8 1.6 2.7 2 1 0 2 2 2 0 Coiled-coil receptor-binding R-domain of colicin E2 NRBF2 PF08961.10 OQS07420.1 - 0.32 10.6 10.0 0.1 12.2 0.4 2.9 2 1 1 3 3 3 0 Nuclear receptor-binding factor 2, autophagy regulator CALCOCO1 PF07888.11 OQS07420.1 - 3 6.6 27.1 0.22 10.4 7.7 3.4 2 1 1 3 3 3 0 Calcium binding and coiled-coil domain (CALCOCO1) like WSN PF02206.18 OQS07421.1 - 0.013 15.4 0.1 0.04 13.8 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function Glyco_hydro_47 PF01532.20 OQS07422.1 - 3.1e-113 379.1 0.0 3.9e-113 378.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 PA PF02225.22 OQS07422.1 - 4.5e-08 33.0 0.0 1e-07 31.8 0.0 1.6 1 0 0 1 1 1 1 PA domain PRKCSH PF07915.13 OQS07422.1 - 4e-06 27.8 0.6 1.5e-05 25.9 0.3 2.2 2 0 0 2 2 2 1 Glucosidase II beta subunit-like protein PRKCSH_1 PF13015.6 OQS07422.1 - 0.015 15.0 0.1 0.028 14.1 0.1 1.4 1 0 0 1 1 1 0 Glucosidase II beta subunit-like protein Ras PF00071.22 OQS07423.1 - 1.3e-30 106.1 0.0 2.2e-30 105.4 0.0 1.3 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OQS07423.1 - 3e-23 82.3 0.0 5.2e-23 81.6 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 OQS07423.1 - 1.9e-07 31.2 0.0 5.8e-07 29.6 0.0 1.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase Arf PF00025.21 OQS07423.1 - 2.9e-07 30.1 0.0 7.4e-07 28.8 0.0 1.6 1 1 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 OQS07423.1 - 0.00068 19.1 0.0 0.00093 18.6 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 OQS07423.1 - 0.001 18.7 0.0 0.0024 17.4 0.0 1.7 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 OQS07423.1 - 0.0042 17.0 0.0 0.03 14.2 0.0 2.1 2 0 0 2 2 2 1 RsgA GTPase AAA_22 PF13401.6 OQS07423.1 - 0.049 13.9 0.0 0.14 12.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 OQS07423.1 - 3.2 8.3 5.1 2.5 8.6 2.5 2.4 1 1 1 2 2 2 0 ABC transporter Sec7 PF01369.20 OQS07424.1 - 5.6e-59 198.9 0.0 1e-58 198.1 0.0 1.4 1 0 0 1 1 1 1 Sec7 domain PH PF00169.29 OQS07424.1 - 3.6e-15 56.4 0.7 6.5e-08 33.0 0.1 2.9 2 0 0 2 2 2 2 PH domain PH_11 PF15413.6 OQS07424.1 - 0.002 18.5 2.4 0.45 11.0 0.5 3.1 2 1 0 2 2 2 2 Pleckstrin homology domain PH_6 PF15406.6 OQS07424.1 - 0.016 15.5 0.1 0.41 10.9 0.1 2.9 3 0 0 3 3 3 0 Pleckstrin homology domain YnfE PF17452.2 OQS07425.1 - 0.026 14.8 0.9 0.1 12.9 0.1 2.4 2 0 0 2 2 2 0 Uncharacterized YnfE-like COMP PF11598.8 OQS07425.1 - 0.059 13.9 0.1 0.059 13.9 0.1 3.2 4 1 0 4 4 4 0 Cartilage oligomeric matrix protein DUF4745 PF15923.5 OQS07425.1 - 0.18 11.8 0.9 1.2 9.1 0.3 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4745) Chordopox_RPO7 PF05864.12 OQS07425.1 - 0.32 11.3 1.7 29 5.0 0.6 2.8 2 0 0 2 2 2 0 Chordopoxvirus DNA-directed RNA polymerase 7 kDa polypeptide (RPO7) V_ATPase_I PF01496.19 OQS07425.1 - 2.5 5.9 19.9 0.23 9.4 13.8 1.8 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family FlaC_arch PF05377.11 OQS07425.1 - 3.3 8.2 7.8 3.7 8.0 0.4 3.6 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) ABC_tran PF00005.27 OQS07426.1 - 1e-39 136.2 0.0 8.3e-24 84.7 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 OQS07426.1 - 2e-28 99.8 26.5 3.4e-19 69.6 7.3 2.3 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.19 OQS07426.1 - 5.5e-09 35.8 3.3 0.0027 17.2 0.0 3.8 2 2 0 4 4 4 2 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 OQS07426.1 - 4.8e-06 26.6 0.0 0.036 14.0 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_29 PF13555.6 OQS07426.1 - 0.0045 16.7 0.0 1.9 8.3 0.0 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_16 PF13191.6 OQS07426.1 - 0.0048 17.3 0.1 5.7 7.3 0.0 3.1 3 1 0 3 3 3 2 AAA ATPase domain MMR_HSR1 PF01926.23 OQS07426.1 - 0.006 16.7 0.0 1.4 9.0 0.0 2.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_21 PF13304.6 OQS07426.1 - 0.0061 16.4 1.0 14 5.4 0.2 3.6 3 1 1 4 4 4 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 OQS07426.1 - 0.018 15.6 0.1 4.6 7.7 0.2 2.3 2 0 0 2 2 2 0 AAA domain Dynamin_N PF00350.23 OQS07426.1 - 0.055 13.5 1.1 10 6.1 0.0 2.6 2 0 0 2 2 2 0 Dynamin family AAA_22 PF13401.6 OQS07426.1 - 0.061 13.6 1.0 45 4.3 0.0 3.5 2 1 0 2 2 2 0 AAA domain T2SSE PF00437.20 OQS07426.1 - 0.14 11.2 0.0 0.87 8.6 0.0 2.1 2 0 0 2 2 2 0 Type II/IV secretion system protein IIGP PF05049.13 OQS07426.1 - 0.17 10.9 0.1 1.8 7.5 0.0 2.3 2 0 0 2 2 2 0 Interferon-inducible GTPase (IIGP) AAA_24 PF13479.6 OQS07426.1 - 0.25 11.1 0.0 2.6 7.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain PRK PF00485.18 OQS07426.1 - 0.5 10.1 1.9 0.52 10.0 0.3 1.8 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family LRR_6 PF13516.6 OQS07428.1 - 4.3e-11 41.9 26.3 0.16 12.1 0.0 9.2 9 0 0 9 9 9 5 Leucine Rich repeat LRR_4 PF12799.7 OQS07428.1 - 0.0013 19.1 0.1 0.0013 19.1 0.1 6.2 5 3 0 7 7 7 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 OQS07428.1 - 0.021 14.6 1.2 0.021 14.6 1.2 5.7 5 1 1 6 6 6 0 Leucine rich repeat T3RM_EcoP15I_C PF18273.1 OQS07428.1 - 0.1 12.9 0.1 0.94 9.8 0.0 2.5 2 0 0 2 2 2 0 Type III R-M EcoP15I C-terminal domain LRR_1 PF00560.33 OQS07428.1 - 3.4 8.6 15.2 1.6e+02 3.5 0.1 7.6 8 2 1 9 9 9 0 Leucine Rich Repeat Myb_DNA-binding PF00249.31 OQS07429.1 - 4.6e-15 55.5 0.0 1.6e-06 28.2 0.0 3.7 3 1 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OQS07429.1 - 1.6e-13 50.7 0.0 2.6e-05 24.4 0.0 3.7 1 1 2 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OQS07429.1 - 0.00062 19.6 0.2 0.0014 18.5 0.0 1.7 2 0 0 2 2 2 1 Myb DNA-binding like Rap1_C PF11626.8 OQS07429.1 - 0.063 13.4 0.0 0.13 12.4 0.0 1.5 1 0 0 1 1 1 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain SANT_DAMP1_like PF16282.5 OQS07429.1 - 0.4 10.9 3.3 11 6.3 0.1 3.6 3 1 1 4 4 4 0 SANT/Myb-like domain of DAMP1 Tim17 PF02466.19 OQS07430.1 - 0.0024 18.2 5.1 0.039 14.3 5.1 2.2 1 1 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Bacteriocin_IIc PF10439.9 OQS07430.1 - 0.064 13.4 5.5 0.68 10.1 0.9 2.3 2 0 0 2 2 2 0 Bacteriocin class II with double-glycine leader peptide Hydrolase_4 PF12146.8 OQS07431.1 - 2.7e-10 39.9 0.1 1.6e-06 27.6 0.2 2.3 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 OQS07431.1 - 2.4e-09 37.2 0.2 4.6e-06 26.5 0.2 2.2 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 OQS07431.1 - 2.5e-05 25.0 0.6 6.7e-05 23.6 0.1 1.8 2 1 1 3 3 3 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 OQS07431.1 - 0.0004 19.9 0.0 0.011 15.2 0.0 2.2 1 1 0 1 1 1 1 Prolyl oligopeptidase family DLH PF01738.18 OQS07431.1 - 0.00092 18.8 0.0 0.019 14.5 0.0 2.1 2 0 0 2 2 2 1 Dienelactone hydrolase family Abhydrolase_2 PF02230.16 OQS07431.1 - 0.0026 17.6 0.0 0.017 15.0 0.0 2.1 1 1 0 1 1 1 1 Phospholipase/Carboxylesterase FSH1 PF03959.13 OQS07431.1 - 0.074 12.7 0.0 0.11 12.2 0.0 1.2 1 0 0 1 1 1 0 Serine hydrolase (FSH1) DUF818 PF05677.12 OQS07431.1 - 0.23 10.4 0.1 0.88 8.5 0.1 1.8 2 0 0 2 2 2 0 Chlamydia CHLPS protein (DUF818) Methyltransf_25 PF13649.6 OQS07433.1 - 0.13 13.0 0.0 0.72 10.6 0.0 2.2 2 1 1 3 3 3 0 Methyltransferase domain Ank_2 PF12796.7 OQS07434.1 - 4.6e-31 107.2 0.5 4.9e-18 65.5 0.0 4.6 3 1 2 5 5 5 3 Ankyrin repeats (3 copies) TIR_2 PF13676.6 OQS07434.1 - 5.1e-26 91.6 0.0 3.5e-18 66.3 0.0 2.4 2 0 0 2 2 2 2 TIR domain Ank_3 PF13606.6 OQS07434.1 - 9.8e-26 87.0 0.6 1.8e-07 30.9 0.0 6.5 5 1 1 6 6 6 5 Ankyrin repeat Ank PF00023.30 OQS07434.1 - 2.2e-23 81.6 1.6 1e-07 32.1 0.0 5.6 5 0 0 5 5 5 5 Ankyrin repeat Ank_4 PF13637.6 OQS07434.1 - 4.9e-23 81.2 0.1 3e-13 50.0 0.0 4.7 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 OQS07434.1 - 4.7e-20 71.4 1.0 1.4e-07 31.6 0.0 5.1 4 1 1 5 5 5 3 Ankyrin repeats (many copies) TIR PF01582.20 OQS07434.1 - 2.1e-08 34.2 0.0 3.1e-05 23.8 0.0 2.3 2 0 0 2 2 2 2 TIR domain DUF1863 PF08937.11 OQS07434.1 - 0.0025 18.1 0.6 0.024 14.9 0.0 2.7 3 1 0 3 3 3 1 MTH538 TIR-like domain (DUF1863) DUF5099 PF17025.5 OQS07434.1 - 0.0045 17.4 0.0 0.0088 16.4 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF5099) UDG PF03167.19 OQS07435.1 - 6.2e-13 49.0 0.0 9.5e-13 48.4 0.0 1.3 1 1 0 1 1 1 1 Uracil DNA glycosylase superfamily Ribosomal_L6 PF00347.23 OQS07436.1 - 1.9e-28 98.9 0.4 1e-14 54.9 0.1 2.1 2 0 0 2 2 2 2 Ribosomal protein L6 HtaA PF04213.13 OQS07436.1 - 0.063 13.8 0.2 3.2 8.2 0.0 2.1 1 1 0 2 2 2 0 Htaa DHC_N1 PF08385.12 OQS07437.1 - 9.4e-180 599.0 16.6 9.4e-180 599.0 16.6 3.2 3 0 0 3 3 3 1 Dynein heavy chain, N-terminal region 1 AAA_6 PF12774.7 OQS07437.1 - 8.4e-142 471.9 0.0 5.9e-141 469.2 0.0 2.3 2 0 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 OQS07437.1 - 4e-113 378.5 16.3 4e-113 378.5 16.3 4.0 4 0 0 4 4 3 1 Dynein heavy chain, N-terminal region 2 AAA_8 PF12780.7 OQS07437.1 - 4.8e-86 288.3 0.1 3.5e-85 285.5 0.0 2.5 2 0 0 2 2 2 1 P-loop containing dynein motor region D4 Dynein_C PF18199.1 OQS07437.1 - 4.6e-83 279.0 0.1 2.3e-82 276.7 0.0 2.4 2 0 0 2 2 2 1 Dynein heavy chain C-terminal domain AAA_9 PF12781.7 OQS07437.1 - 1.1e-74 250.3 0.5 1.9e-73 246.2 0.0 3.2 3 0 0 3 3 3 1 ATP-binding dynein motor region AAA_7 PF12775.7 OQS07437.1 - 4.8e-59 198.9 0.8 1.3e-54 184.4 0.0 4.2 4 0 0 4 4 4 1 P-loop containing dynein motor region AAA_lid_11 PF18198.1 OQS07437.1 - 3.8e-48 163.4 0.0 1e-47 162.0 0.0 1.8 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 OQS07437.1 - 5.8e-38 129.6 0.0 1.9e-36 124.7 0.0 3.4 3 0 0 3 3 3 1 Dynein heavy chain region D6 P-loop domain MT PF12777.7 OQS07437.1 - 3.1e-37 128.4 10.4 7.1e-37 127.2 10.4 1.6 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor Dynein_AAA_lid PF17852.1 OQS07437.1 - 5.7e-18 65.2 0.0 2.7e-17 63.0 0.0 2.4 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_lid_1 PF17857.1 OQS07437.1 - 4.9e-15 55.6 2.9 2.2e-14 53.5 0.7 3.2 2 1 0 2 2 2 1 AAA+ lid domain AAA_5 PF07728.14 OQS07437.1 - 1.3e-12 47.9 0.1 1.9e-05 24.7 0.0 5.3 4 1 0 4 4 4 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 OQS07437.1 - 8.8e-05 22.8 1.6 14 5.9 0.1 5.2 4 0 0 4 4 4 0 AAA domain AAA_16 PF13191.6 OQS07437.1 - 0.00018 22.0 0.3 8.3 6.8 0.0 5.3 5 0 0 5 5 5 0 AAA ATPase domain AAA PF00004.29 OQS07437.1 - 0.00019 21.8 4.6 0.42 11.0 0.1 5.4 5 0 0 5 5 4 1 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 OQS07437.1 - 0.0093 16.5 0.5 8.6 6.9 0.0 3.9 3 0 0 3 3 3 0 AAA domain DUF3583 PF12126.8 OQS07437.1 - 0.019 14.4 0.0 0.05 13.0 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3583) His_Phos_2 PF00328.22 OQS07437.1 - 0.023 14.1 0.0 0.096 12.0 0.0 2.1 1 0 0 1 1 1 0 Histidine phosphatase superfamily (branch 2) ABC_tran PF00005.27 OQS07437.1 - 0.026 15.1 0.0 18 5.8 0.0 3.2 2 0 0 2 2 2 0 ABC transporter PrpR_N PF06506.11 OQS07437.1 - 0.09 12.4 0.9 9.3 5.8 0.1 2.6 2 0 0 2 2 2 0 Propionate catabolism activator AAA_29 PF13555.6 OQS07437.1 - 0.13 12.0 0.1 5.6 6.8 0.0 2.8 2 0 0 2 2 2 0 P-loop containing region of AAA domain RNA_helicase PF00910.22 OQS07437.1 - 0.18 12.2 1.2 10 6.5 0.0 3.7 3 0 0 3 3 2 0 RNA helicase AAA_33 PF13671.6 OQS07437.1 - 0.22 11.7 1.1 38 4.4 0.0 3.7 3 0 0 3 3 3 0 AAA domain AAA_23 PF13476.6 OQS07437.1 - 0.58 10.6 0.0 0.58 10.6 0.0 5.8 6 1 0 6 6 3 0 AAA domain MLD PF11647.8 OQS07437.1 - 0.76 10.1 2.7 60 4.0 0.1 4.3 4 0 0 4 4 4 0 Membrane Localization Domain AAA_28 PF13521.6 OQS07437.1 - 1.4 9.2 7.2 7.3 6.8 0.3 3.8 3 0 0 3 3 3 0 AAA domain BK_channel_a PF03493.18 OQS07438.1 - 9.4e-21 73.8 0.4 3e-19 69.0 0.2 2.5 2 0 0 2 2 2 1 Calcium-activated BK potassium channel alpha subunit TrkA_N PF02254.18 OQS07438.1 - 1.4e-06 28.5 0.6 0.0064 16.8 0.1 2.7 3 0 0 3 3 3 2 TrkA-N domain MAF_flag10 PF01973.18 OQS07438.1 - 0.083 12.6 0.0 0.17 11.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function DUF115 SLX9 PF15341.6 OQS07439.1 - 2.3e-15 57.2 11.7 3.8e-15 56.4 11.7 1.4 1 0 0 1 1 1 1 Ribosome biogenesis protein SLX9 Peptidase_S64 PF08192.11 OQS07439.1 - 0.42 9.0 10.6 0.48 8.9 10.6 1.0 1 0 0 1 1 1 0 Peptidase family S64 PET117 PF15786.5 OQS07440.1 - 9.5e-06 25.8 4.4 1.4e-05 25.3 4.4 1.3 1 1 0 1 1 1 1 PET assembly of cytochrome c oxidase, mitochondrial Metallophos PF00149.28 OQS07441.1 - 5.4e-13 49.9 0.0 7.8e-13 49.4 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 OQS07441.1 - 0.00075 19.7 0.0 0.0022 18.2 0.0 1.8 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Epimerase_2 PF02350.19 OQS07441.1 - 0.017 14.0 0.0 0.026 13.4 0.0 1.2 1 0 0 1 1 1 0 UDP-N-acetylglucosamine 2-epimerase UDG PF03167.19 OQS07442.1 - 8.8e-22 77.8 0.0 1.4e-21 77.1 0.0 1.2 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily Mif2_N PF15624.6 OQS07442.1 - 0.062 14.0 0.9 0.094 13.4 0.9 1.3 1 0 0 1 1 1 0 Kinetochore CENP-C fungal homologue, Mif2, N-terminal DAHP_synth_1 PF00793.20 OQS07443.1 - 1.2e-95 319.5 0.0 1.6e-95 319.1 0.0 1.1 1 0 0 1 1 1 1 DAHP synthetase I family TGBp3 PF02495.17 OQS07443.1 - 0.53 10.0 2.6 5.2 6.8 0.1 3.3 4 0 0 4 4 4 0 Triple gene block 3 Flavodoxin_1 PF00258.25 OQS07445.1 - 3.2e-24 85.8 0.1 5.7e-24 84.9 0.1 1.4 1 0 0 1 1 1 1 Flavodoxin FAD_binding_1 PF00667.20 OQS07445.1 - 9.1e-24 84.3 0.1 1.4e-23 83.7 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain HOOK PF05622.12 OQS07446.1 - 0.069 11.3 25.8 0.15 10.2 5.2 2.2 1 1 1 2 2 2 0 HOOK protein Lebercilin PF15619.6 OQS07446.1 - 0.13 11.9 33.2 0.029 14.0 29.2 2.0 2 0 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease DUF2383 PF09537.10 OQS07446.1 - 0.35 11.2 7.9 1.2 9.5 7.9 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF2383) DUF724 PF05266.14 OQS07446.1 - 0.48 10.2 14.6 1.4 8.7 11.2 2.5 1 1 0 2 2 2 0 Protein of unknown function (DUF724) YabA PF06156.13 OQS07446.1 - 0.82 10.3 18.5 0.57 10.9 2.5 3.6 3 1 0 3 3 3 0 Initiation control protein YabA V_ATPase_I PF01496.19 OQS07446.1 - 1.7 6.5 8.9 2.8 5.7 8.9 1.4 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family GAS PF13851.6 OQS07446.1 - 2 7.7 27.3 2.3 7.5 2.9 3.4 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding Jnk-SapK_ap_N PF09744.9 OQS07446.1 - 7.8 6.7 27.9 31 4.8 21.9 2.6 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 SOAR PF16533.5 OQS07446.1 - 8 6.5 14.6 0.62 10.1 4.1 3.8 3 1 1 4 4 4 0 STIM1 Orai1-activating region Ank_2 PF12796.7 OQS07447.1 - 0.0004 20.9 0.1 0.001 19.6 0.1 1.6 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OQS07447.1 - 0.0019 18.4 0.7 0.43 11.0 0.2 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQS07447.1 - 0.0047 17.3 0.5 0.24 12.1 0.0 2.7 2 0 0 2 2 2 1 Ankyrin repeat FYVE PF01363.21 OQS07447.1 - 0.0055 16.8 12.1 0.011 15.9 12.1 1.5 1 0 0 1 1 1 1 FYVE zinc finger Siva PF05458.12 OQS07447.1 - 0.0088 15.7 3.8 0.017 14.8 3.8 1.4 1 0 0 1 1 1 1 Cd27 binding protein (Siva) Ank PF00023.30 OQS07447.1 - 0.27 11.8 1.0 2.9 8.5 0.1 2.5 2 0 0 2 2 2 0 Ankyrin repeat FYVE_2 PF02318.16 OQS07447.1 - 1.7 8.9 10.0 1.3 9.3 7.6 2.0 1 1 1 2 2 2 0 FYVE-type zinc finger Arm PF00514.23 OQS07448.1 - 7e-13 48.1 29.6 0.004 17.2 0.1 11.7 13 1 1 14 14 14 5 Armadillo/beta-catenin-like repeat Vac14_Fab1_bd PF12755.7 OQS07448.1 - 0.01 16.4 2.2 2.5 8.8 0.1 4.4 4 0 0 4 4 4 0 Vacuolar 14 Fab1-binding region UNC45-central PF11701.8 OQS07448.1 - 0.23 11.4 22.2 0.34 10.9 0.2 6.5 5 2 1 6 6 6 0 Myosin-binding striated muscle assembly central HEAT PF02985.22 OQS07448.1 - 0.83 10.1 15.3 19 5.8 0.1 7.4 8 0 0 8 8 8 0 HEAT repeat LRR_8 PF13855.6 OQS07449.1 - 1.7e-05 24.5 4.9 1.7e-05 24.5 4.9 3.0 3 0 0 3 3 3 1 Leucine rich repeat LRR_4 PF12799.7 OQS07449.1 - 0.0071 16.7 10.0 0.0084 16.5 2.5 3.4 2 1 1 3 3 3 1 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 OQS07449.1 - 0.34 11.1 5.5 0.55 10.4 0.0 3.3 3 0 0 3 3 3 0 Leucine Rich repeat TFIIS_C PF01096.18 OQS07450.1 - 4.1e-19 68.2 4.3 4.1e-19 68.2 4.3 2.9 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.16 OQS07450.1 - 2.5e-09 36.9 3.7 2.5e-09 36.9 3.7 2.1 3 0 0 3 3 2 1 RNA polymerases M/15 Kd subunit Zn_Tnp_IS1595 PF12760.7 OQS07450.1 - 6.4e-05 22.8 11.4 8.8e-05 22.4 1.0 2.6 2 1 0 2 2 2 1 Transposase zinc-ribbon domain Nudix_N_2 PF14803.6 OQS07450.1 - 0.013 15.4 2.8 0.013 15.4 2.8 2.4 2 0 0 2 2 2 0 Nudix N-terminal YacG PF03884.14 OQS07450.1 - 0.018 14.7 2.2 0.018 14.7 2.2 2.7 3 0 0 3 3 3 0 DNA gyrase inhibitor YacG Lar_restr_allev PF14354.6 OQS07450.1 - 0.57 10.6 8.1 1.1 9.7 0.9 2.5 2 0 0 2 2 2 0 Restriction alleviation protein Lar zf-ribbon_3 PF13248.6 OQS07450.1 - 0.61 9.6 13.6 0.38 10.2 0.7 3.9 4 1 0 4 4 4 0 zinc-ribbon domain Elf1 PF05129.13 OQS07450.1 - 2.5 8.2 9.2 0.24 11.5 0.5 2.7 2 1 0 2 2 2 0 Transcription elongation factor Elf1 like HypA PF01155.19 OQS07450.1 - 4.1 7.5 8.5 0.22 11.6 0.4 2.6 1 1 2 3 3 3 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Rubredoxin PF00301.20 OQS07450.1 - 5.9 7.0 14.8 5.4 7.1 0.1 3.7 4 0 0 4 4 4 0 Rubredoxin DpnI PF06044.12 OQS07450.1 - 8.8 5.9 9.5 0.62 9.7 0.7 2.0 1 1 0 2 2 2 0 Dam-replacing family RecR PF02132.15 OQS07450.1 - 9.2 5.9 9.0 8.3 6.1 3.5 2.5 2 1 0 2 2 2 0 RecR protein Peptidase_M16 PF00675.20 OQS07451.1 - 2.6e-35 121.6 0.0 1.2e-34 119.4 0.0 2.0 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 OQS07451.1 - 4.8e-33 114.7 0.0 9e-33 113.8 0.0 1.5 1 0 0 1 1 1 1 Peptidase M16 inactive domain Sun2_CC2 PF18580.1 OQS07451.1 - 0.032 14.5 0.1 0.085 13.1 0.1 1.7 1 0 0 1 1 1 0 SUN2 coiled coil domain 2 V-SNARE PF05008.15 OQS07452.1 - 1e-12 48.2 5.2 1e-12 48.2 5.2 2.4 1 1 2 3 3 3 1 Vesicle transport v-SNARE protein N-terminus V-SNARE_C PF12352.8 OQS07452.1 - 4.5e-07 30.1 3.9 5.9e-07 29.7 0.9 2.4 2 1 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus BRE1 PF08647.11 OQS07452.1 - 0.021 14.9 21.4 0.085 12.9 10.1 2.6 1 1 1 2 2 2 0 BRE1 E3 ubiquitin ligase SelB-wing_1 PF09105.10 OQS07452.1 - 0.08 12.9 0.2 8.1 6.5 0.0 2.6 2 0 0 2 2 2 0 Elongation factor SelB, winged helix Spectrin PF00435.21 OQS07452.1 - 0.12 12.9 16.3 1.7 9.1 10.1 2.3 1 1 1 2 2 2 0 Spectrin repeat DUF1664 PF07889.12 OQS07452.1 - 0.15 12.1 15.0 0.32 11.0 2.2 2.8 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) Nup54 PF13874.6 OQS07452.1 - 0.17 12.0 15.1 0.061 13.4 11.1 1.9 1 1 1 2 2 2 0 Nucleoporin complex subunit 54 Phosducin PF02114.16 OQS07452.1 - 0.18 10.7 6.2 0.21 10.5 6.2 1.2 1 0 0 1 1 1 0 Phosducin DUF2203 PF09969.9 OQS07452.1 - 0.24 12.1 12.3 3.3 8.5 0.2 2.8 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) Caskin-tail PF16632.5 OQS07452.1 - 0.35 11.3 5.2 0.27 11.7 1.0 2.6 2 2 0 2 2 2 0 C-terminal region of Caskin DUF4107 PF13389.6 OQS07452.1 - 1 9.5 4.9 6.6 6.9 0.9 2.7 1 1 2 3 3 3 0 Protein of unknown function (DUF4107) YgbB PF02542.16 OQS07452.1 - 1.3 9.3 7.2 0.78 10.0 1.9 2.0 1 1 1 2 2 2 0 YgbB family Exonuc_VII_L PF02601.15 OQS07452.1 - 3.3 7.2 16.0 5.4 6.5 16.0 1.4 1 1 0 1 1 1 0 Exonuclease VII, large subunit PAXNEB PF05625.11 OQS07453.1 - 8e-66 222.7 0.2 1e-65 222.3 0.2 1.0 1 0 0 1 1 1 1 PAXNEB protein Methyltransf_11 PF08241.12 OQS07454.1 - 1.1e-15 58.0 0.0 1.7e-15 57.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OQS07454.1 - 3e-12 47.1 0.0 5e-12 46.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OQS07454.1 - 1e-09 38.4 0.0 1.1e-09 38.2 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OQS07454.1 - 1.2e-08 35.6 0.0 1.9e-08 35.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 OQS07454.1 - 5.9e-06 25.8 0.1 8.1e-06 25.3 0.1 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 OQS07454.1 - 2e-05 24.5 0.0 2.6e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 OQS07454.1 - 0.0059 15.9 0.1 0.0068 15.7 0.1 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase NodS PF05401.11 OQS07454.1 - 0.022 14.4 0.0 0.029 14.0 0.0 1.2 1 0 0 1 1 1 0 Nodulation protein S (NodS) N6_N4_Mtase PF01555.18 OQS07454.1 - 0.035 13.8 0.1 0.13 11.9 0.0 1.9 1 1 1 2 2 2 0 DNA methylase Methyltransf_PK PF05891.12 OQS07454.1 - 0.046 13.2 0.2 0.09 12.3 0.1 1.6 2 1 0 2 2 2 0 AdoMet dependent proline di-methyltransferase RNA_pol_Rpb2_4 PF04566.13 OQS07455.1 - 8.5 6.8 6.2 4.6 7.6 1.1 3.0 3 0 0 3 3 3 0 RNA polymerase Rpb2, domain 4 Mito_carr PF00153.27 OQS07456.1 - 1.6e-58 194.6 3.8 1.5e-20 72.9 0.1 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_1 PF00036.32 OQS07456.1 - 0.58 9.8 3.0 18 5.1 0.0 3.0 3 0 0 3 3 3 0 EF hand EGF_2 PF07974.13 OQS07457.1 - 9.3e-13 48.3 65.7 2e-05 24.8 10.4 5.4 5 0 0 5 5 5 5 EGF-like domain EGF PF00008.27 OQS07457.1 - 1.6 9.1 52.3 0.11 12.8 4.0 5.6 5 0 0 5 5 5 0 EGF-like domain Kelch_4 PF13418.6 OQS07458.1 - 7.8e-31 105.8 2.9 5.9e-09 35.8 0.0 5.2 3 2 2 5 5 5 5 Galactose oxidase, central domain Kelch_5 PF13854.6 OQS07458.1 - 6.3e-29 99.5 0.3 4.6e-08 32.9 0.1 5.2 5 0 0 5 5 5 5 Kelch motif Kelch_3 PF13415.6 OQS07458.1 - 1.6e-23 82.5 0.9 6.2e-08 32.7 0.0 5.2 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_2 PF07646.15 OQS07458.1 - 9.1e-21 73.0 2.2 7e-05 22.6 0.0 5.3 5 0 0 5 5 5 4 Kelch motif Kelch_1 PF01344.25 OQS07458.1 - 2.9e-20 71.6 4.0 6.9e-08 32.0 0.0 5.0 5 0 0 5 5 5 4 Kelch motif Kelch_6 PF13964.6 OQS07458.1 - 3e-18 65.4 1.9 6e-07 29.5 0.0 4.6 3 2 2 5 5 5 4 Kelch motif PfkB PF00294.24 OQS07458.1 - 0.055 12.8 0.0 0.075 12.3 0.0 1.2 1 0 0 1 1 1 0 pfkB family carbohydrate kinase Syndecan PF01034.20 OQS07459.1 - 0.49 10.4 0.1 0.49 10.4 0.1 2.6 3 0 0 3 3 3 0 Syndecan domain Pyr_redox_2 PF07992.14 OQS07460.1 - 1.1e-44 152.8 0.0 1.8e-44 152.2 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 OQS07460.1 - 4.8e-11 43.1 0.0 4.1e-07 30.4 0.0 3.1 3 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase EF-hand_6 PF13405.6 OQS07460.1 - 2.2e-08 33.4 1.3 0.0028 17.4 0.1 2.6 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.6 OQS07460.1 - 6.3e-08 33.0 0.2 0.00026 21.4 0.0 2.5 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 OQS07460.1 - 6.4e-08 31.6 1.6 0.00037 19.8 0.1 2.6 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 OQS07460.1 - 2.3e-07 30.5 0.1 0.012 15.5 0.1 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 OQS07460.1 - 0.0012 18.3 2.5 0.011 15.2 0.1 2.4 2 0 0 2 2 2 1 EF hand UBA_5 PF16577.5 OQS07460.1 - 0.0075 16.4 0.0 0.42 10.8 0.0 2.4 2 0 0 2 2 2 1 UBA domain K_oxygenase PF13434.6 OQS07460.1 - 0.071 12.2 0.0 11 5.0 0.0 2.3 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) V-SNARE PF05008.15 OQS07460.1 - 0.19 12.1 0.1 19 5.7 0.0 2.4 2 0 0 2 2 2 0 Vesicle transport v-SNARE protein N-terminus Pkinase PF00069.25 OQS07461.1 - 3.9e-35 121.5 0.1 9.8e-31 107.1 0.0 2.0 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OQS07461.1 - 8.4e-17 61.3 0.1 1.5e-16 60.5 0.1 1.4 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.23 OQS07461.1 - 0.022 14.7 0.0 0.033 14.1 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 OQS07461.1 - 0.034 13.1 0.1 0.046 12.7 0.1 1.1 1 0 0 1 1 1 0 Haspin like kinase domain Pkinase_fungal PF17667.1 OQS07461.1 - 0.076 11.8 0.0 0.098 11.4 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase Isochorismatase PF00857.20 OQS07462.1 - 4.8e-34 118.1 0.0 5.9e-34 117.7 0.0 1.2 1 1 0 1 1 1 1 Isochorismatase family AAA_5 PF07728.14 OQS07463.1 - 2.9e-120 396.6 0.2 1.4e-21 76.9 0.0 9.6 9 0 0 9 9 9 9 AAA domain (dynein-related subfamily) AAA_lid_7 PF17867.1 OQS07463.1 - 1.1e-59 199.2 4.1 1.8e-16 60.3 0.0 8.2 7 0 0 7 7 7 5 Midasin AAA lid domain AAA_3 PF07726.11 OQS07463.1 - 8.7e-31 106.5 0.0 1.1e-09 38.2 0.0 7.3 8 0 0 8 8 7 4 ATPase family associated with various cellular activities (AAA) AAA PF00004.29 OQS07463.1 - 3.7e-26 92.1 0.0 0.00027 21.4 0.0 7.7 7 0 0 7 7 6 5 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 OQS07463.1 - 5.7e-26 91.1 0.6 0.00017 21.2 0.1 7.0 6 0 0 6 6 6 5 P-loop containing dynein motor region AAA_lid_5 PF17865.1 OQS07463.1 - 6.4e-26 90.5 0.4 3.4e-25 88.2 0.1 2.6 2 0 0 2 2 1 1 Midasin AAA lid domain AAA_16 PF13191.6 OQS07463.1 - 1.6e-24 87.2 16.0 0.00062 20.2 0.0 8.9 6 2 0 6 6 6 6 AAA ATPase domain AAA_22 PF13401.6 OQS07463.1 - 1.2e-21 77.5 5.1 0.0019 18.5 0.1 8.3 7 1 0 7 7 6 5 AAA domain Dynein_heavy PF03028.15 OQS07463.1 - 3.7e-20 72.2 0.0 0.00094 19.3 0.0 6.1 5 0 0 5 5 5 4 Dynein heavy chain region D6 P-loop domain AAA_6 PF12774.7 OQS07463.1 - 7.6e-18 64.6 1.9 0.11 11.4 0.0 8.9 9 0 0 9 9 9 4 Hydrolytic ATP binding site of dynein motor region TsaE PF02367.17 OQS07463.1 - 1.7e-16 60.3 1.4 0.0031 17.5 0.0 6.8 6 0 0 6 6 6 3 Threonylcarbamoyl adenosine biosynthesis protein TsaE Sigma54_activat PF00158.26 OQS07463.1 - 2.6e-16 59.8 0.0 0.0076 16.0 0.0 6.7 6 0 0 6 6 6 4 Sigma-54 interaction domain AAA_18 PF13238.6 OQS07463.1 - 6.7e-16 59.0 4.2 0.27 11.8 0.0 7.7 7 0 0 7 7 6 5 AAA domain Zeta_toxin PF06414.12 OQS07463.1 - 7.7e-14 51.4 2.2 0.75 9.0 0.0 8.2 9 0 0 9 9 8 3 Zeta toxin AAA_30 PF13604.6 OQS07463.1 - 5.7e-13 49.0 0.0 0.38 10.4 0.0 7.2 6 2 0 6 6 6 3 AAA domain ABC_tran PF00005.27 OQS07463.1 - 6.7e-13 49.3 15.4 0.0013 19.2 0.5 8.2 7 2 0 7 7 6 3 ABC transporter AAA_14 PF13173.6 OQS07463.1 - 1.6e-12 47.6 0.0 0.037 14.1 0.0 6.8 7 0 0 7 7 6 1 AAA domain AAA_33 PF13671.6 OQS07463.1 - 3.7e-12 46.6 0.4 0.32 11.1 0.0 7.1 6 0 0 6 6 6 2 AAA domain NACHT PF05729.12 OQS07463.1 - 3.7e-11 43.2 2.6 0.24 11.3 0.1 7.0 6 0 0 6 6 5 2 NACHT domain T2SSE PF00437.20 OQS07463.1 - 6e-11 41.9 0.5 0.024 13.7 0.0 6.5 6 0 0 6 6 6 1 Type II/IV secretion system protein AAA_29 PF13555.6 OQS07463.1 - 1.2e-10 40.9 0.6 0.5 10.1 0.0 6.7 6 0 0 6 6 6 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 OQS07463.1 - 2.3e-10 40.6 0.2 0.082 12.8 0.0 6.4 6 0 0 6 6 6 2 RsgA GTPase Sigma54_activ_2 PF14532.6 OQS07463.1 - 3.7e-10 40.1 3.8 0.034 14.3 0.1 6.4 6 0 0 6 6 6 2 Sigma-54 interaction domain Rad17 PF03215.15 OQS07463.1 - 6.3e-10 39.3 0.8 0.52 10.2 0.0 6.3 6 0 0 6 6 6 1 Rad17 P-loop domain AAA_8 PF12780.7 OQS07463.1 - 7e-10 38.7 0.1 0.43 9.8 0.0 5.6 5 0 0 5 5 5 3 P-loop containing dynein motor region D4 RNA_helicase PF00910.22 OQS07463.1 - 8.2e-10 39.0 1.2 0.14 12.6 0.0 7.4 7 0 0 7 7 6 1 RNA helicase AAA_25 PF13481.6 OQS07463.1 - 8.6e-10 38.5 4.7 0.36 10.4 0.1 6.1 6 0 0 6 6 6 3 AAA domain Mg_chelatase PF01078.21 OQS07463.1 - 9.6e-10 38.2 4.6 11 5.4 0.0 8.9 9 1 1 10 10 9 0 Magnesium chelatase, subunit ChlI RuvB_N PF05496.12 OQS07463.1 - 9.9e-10 38.4 1.5 2.7 7.7 0.0 6.7 6 0 0 6 6 6 1 Holliday junction DNA helicase RuvB P-loop domain AAA_28 PF13521.6 OQS07463.1 - 3.3e-08 33.9 11.4 1.2 9.3 0.0 6.7 7 0 0 7 7 6 2 AAA domain PduV-EutP PF10662.9 OQS07463.1 - 1e-07 31.8 1.9 0.11 12.2 0.0 5.6 6 0 0 6 6 5 2 Ethanolamine utilisation - propanediol utilisation AAA_19 PF13245.6 OQS07463.1 - 4e-07 30.5 12.2 1.3 9.4 0.1 7.3 7 2 0 7 7 5 2 AAA domain ATPase_2 PF01637.18 OQS07463.1 - 1e-06 28.9 0.0 5.4 6.9 0.0 6.2 6 0 0 6 6 6 0 ATPase domain predominantly from Archaea DUF815 PF05673.13 OQS07463.1 - 1.4e-06 27.7 0.8 1.1 8.3 0.0 6.0 6 0 0 6 6 6 1 Protein of unknown function (DUF815) IstB_IS21 PF01695.17 OQS07463.1 - 4.5e-06 26.5 1.4 2.6 7.8 0.0 5.9 6 0 0 6 6 5 1 IstB-like ATP binding protein SRP54 PF00448.22 OQS07463.1 - 8.9e-06 25.5 2.2 3.4 7.2 0.2 5.4 5 0 0 5 5 5 0 SRP54-type protein, GTPase domain TniB PF05621.11 OQS07463.1 - 1.1e-05 25.0 0.0 2.5 7.4 0.0 5.7 6 0 0 6 6 6 1 Bacterial TniB protein VWA_2 PF13519.6 OQS07463.1 - 1.2e-05 25.9 0.2 9.2e-05 23.0 0.2 2.8 1 0 0 1 1 1 1 von Willebrand factor type A domain Roc PF08477.13 OQS07463.1 - 1.2e-05 25.5 2.6 18 5.6 0.0 6.6 6 0 0 6 6 6 0 Ras of Complex, Roc, domain of DAPkinase Viral_helicase1 PF01443.18 OQS07463.1 - 4.4e-05 23.3 0.2 3 7.5 0.0 4.8 5 0 0 5 5 4 1 Viral (Superfamily 1) RNA helicase ATPase PF06745.13 OQS07463.1 - 0.00068 19.0 0.2 10 5.4 0.0 4.5 5 0 0 5 5 4 0 KaiC MMR_HSR1 PF01926.23 OQS07463.1 - 0.0048 17.0 0.4 22 5.2 0.0 4.7 6 0 0 6 6 3 0 50S ribosome-binding GTPase TIP49 PF06068.13 OQS07463.1 - 0.0058 15.9 0.8 54 2.8 0.0 4.9 5 0 0 5 5 5 0 TIP49 P-loop domain tRNA_lig_kinase PF08303.11 OQS07463.1 - 0.0069 16.5 2.1 4 7.5 0.0 3.2 3 0 0 3 3 2 0 tRNA ligase kinase domain SRPRB PF09439.10 OQS07463.1 - 0.0076 15.7 1.3 38 3.7 0.1 5.4 6 0 0 6 6 6 0 Signal recognition particle receptor beta subunit cobW PF02492.19 OQS07463.1 - 0.012 15.2 7.6 24 4.5 0.1 5.4 6 0 0 6 6 5 0 CobW/HypB/UreG, nucleotide-binding domain NTPase_1 PF03266.15 OQS07463.1 - 0.031 14.2 5.4 25 4.7 0.0 5.6 6 0 0 6 6 6 0 NTPase Cytidylate_kin PF02224.18 OQS07463.1 - 0.042 13.6 0.3 8.6 6.0 0.0 3.4 3 0 0 3 3 2 0 Cytidylate kinase Bac_DnaA PF00308.18 OQS07463.1 - 0.055 13.3 0.4 61 3.4 0.0 4.4 5 0 0 5 5 4 0 Bacterial dnaA protein CbbQ_C PF08406.10 OQS07463.1 - 0.15 12.3 0.1 4.9 7.5 0.0 3.3 3 0 0 3 3 2 0 CbbQ/NirQ/NorQ C-terminal AAA_23 PF13476.6 OQS07463.1 - 0.21 12.1 0.0 0.33 11.4 0.0 8.4 8 1 0 8 8 6 0 AAA domain dNK PF01712.19 OQS07463.1 - 0.38 10.6 7.3 8.6 6.1 0.1 5.5 7 0 0 7 7 4 0 Deoxynucleoside kinase CPT PF07931.12 OQS07463.1 - 0.58 10.0 3.1 55 3.5 0.0 5.0 6 0 0 6 6 4 0 Chloramphenicol phosphotransferase-like protein PI3_PI4_kinase PF00454.27 OQS07464.1 - 1.2e-51 176.0 0.0 3.8e-51 174.3 0.0 1.9 2 0 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.20 OQS07464.1 - 2.5e-13 49.6 0.2 2.5e-12 46.4 0.0 2.9 3 0 0 3 3 3 1 FATC domain BTB_2 PF02214.22 OQS07464.1 - 2.8e-11 43.6 0.0 1.2e-10 41.6 0.0 2.2 1 0 0 1 1 1 1 BTB/POZ domain SPRY PF00622.28 OQS07464.1 - 0.00013 22.0 0.1 0.0003 20.9 0.1 1.6 1 0 0 1 1 1 1 SPRY domain ANAPC3 PF12895.7 OQS07464.1 - 0.12 12.6 0.0 0.44 10.8 0.0 2.0 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 DUF1687 PF07955.11 OQS07464.1 - 0.13 12.7 0.2 0.42 11.1 0.2 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1687) MYO10_CC PF16735.5 OQS07464.1 - 0.6 10.2 6.3 0.68 10.1 0.2 2.8 2 0 0 2 2 2 0 Unconventional myosin-X coiled coil domain Peptidase_S10 PF00450.22 OQS07465.1 - 1.4e-104 350.8 1.7 1.7e-104 350.5 1.7 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase LBP_M PF17385.2 OQS07465.1 - 0.045 13.3 0.0 0.98 8.9 0.0 2.2 2 0 0 2 2 2 0 Lacto-N-biose phosphorylase central domain Abhydrolase_6 PF12697.7 OQS07465.1 - 0.07 13.7 0.0 3.4 8.2 0.0 2.2 2 0 0 2 2 2 0 Alpha/beta hydrolase family Peptidase_S8 PF00082.22 OQS07469.1 - 9.5e-43 146.6 5.9 3e-42 144.9 5.9 1.8 1 0 0 1 1 1 1 Subtilase family Ricin_B_lectin PF00652.22 OQS07469.1 - 3.1e-08 33.9 0.0 5.4e-08 33.1 0.0 1.4 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.6 OQS07469.1 - 0.032 14.9 0.1 0.12 13.2 0.0 1.9 2 0 0 2 2 2 0 Ricin-type beta-trefoil lectin domain-like bZIP_1 PF00170.21 OQS07471.1 - 9.7e-10 38.4 15.6 2.6e-09 37.1 15.6 1.7 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 OQS07471.1 - 0.0017 18.4 15.0 0.0017 18.4 15.0 2.6 2 1 0 2 2 2 1 Basic region leucine zipper bZIP_Maf PF03131.17 OQS07471.1 - 0.0023 18.4 8.6 0.0049 17.3 8.6 1.5 1 0 0 1 1 1 1 bZIP Maf transcription factor PKcGMP_CC PF16808.5 OQS07471.1 - 0.0048 16.7 5.6 0.77 9.7 1.2 2.5 2 0 0 2 2 2 2 Coiled-coil N-terminus of cGMP-dependent protein kinase DUF3275 PF11679.8 OQS07471.1 - 0.066 13.2 4.4 0.43 10.5 0.5 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3275) Csm1_N PF18504.1 OQS07471.1 - 0.097 13.0 9.3 3.1 8.2 4.6 2.5 2 0 0 2 2 2 0 Csm1 N-terminal domain V_ATPase_I PF01496.19 OQS07471.1 - 0.17 9.8 5.9 0.3 9.0 5.9 1.4 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Glutaredoxin2_C PF04399.13 OQS07471.1 - 0.21 11.4 4.0 3.1 7.6 0.6 2.4 2 0 0 2 2 2 0 Glutaredoxin 2, C terminal domain YabA PF06156.13 OQS07471.1 - 0.29 11.8 9.8 0.33 11.6 3.7 3.4 2 2 2 4 4 4 0 Initiation control protein YabA DUF641 PF04859.12 OQS07471.1 - 0.41 11.0 8.2 0.87 9.9 8.2 1.6 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) FapA PF03961.13 OQS07471.1 - 2.5 6.6 10.4 3.5 6.1 10.4 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A Pkinase PF00069.25 OQS07472.1 - 3.4e-108 361.0 0.1 3e-53 180.9 0.0 2.0 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OQS07472.1 - 8.8e-61 205.4 0.0 9.9e-31 106.9 0.0 2.4 2 1 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 OQS07472.1 - 1.6e-12 47.4 2.2 4.6e-05 22.9 0.0 3.2 3 0 0 3 3 3 3 Kinase-like Kdo PF06293.14 OQS07472.1 - 5.1e-07 29.3 0.1 0.011 15.1 0.1 2.4 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 OQS07472.1 - 0.0012 18.4 0.2 0.34 10.5 0.0 2.4 2 0 0 2 2 2 2 RIO1 family APH PF01636.23 OQS07472.1 - 0.0029 17.6 2.3 0.24 11.3 0.2 2.8 2 1 1 3 3 3 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 OQS07472.1 - 0.014 14.2 0.0 0.75 8.5 0.0 2.3 2 0 0 2 2 2 0 Fungal protein kinase Med6 PF04934.14 OQS07473.1 - 4.1e-36 123.7 3.1 5.8e-36 123.2 3.1 1.2 1 0 0 1 1 1 1 MED6 mediator sub complex component Arm PF00514.23 OQS07474.1 - 1.4e-27 94.9 11.7 3.8e-10 39.4 0.0 7.4 8 0 0 8 8 8 6 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 OQS07474.1 - 3.9e-07 30.4 2.3 1.1 9.7 0.1 4.7 3 1 1 5 5 5 3 HEAT repeats Arm_3 PF16186.5 OQS07474.1 - 0.0003 20.3 0.0 0.00094 18.7 0.0 1.8 2 0 0 2 2 2 1 Atypical Arm repeat HEAT_EZ PF13513.6 OQS07474.1 - 0.0029 18.1 4.6 0.96 10.0 0.0 4.6 4 1 1 5 5 5 2 HEAT-like repeat Cnd1 PF12717.7 OQS07474.1 - 0.014 15.5 0.7 0.36 10.9 0.1 3.2 3 1 1 4 4 4 0 non-SMC mitotic condensation complex subunit 1 RICTOR_V PF14668.6 OQS07474.1 - 0.02 15.2 0.4 15 5.9 0.0 4.6 3 2 2 5 5 5 0 Rapamycin-insensitive companion of mTOR, domain 5 Pkinase PF00069.25 OQS07476.1 - 1.1e-53 182.3 0.0 1.7e-53 181.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQS07476.1 - 4.9e-20 71.9 0.0 8.8e-20 71.1 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 OQS07476.1 - 9.9e-05 22.4 0.0 0.00017 21.6 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 OQS07476.1 - 0.0022 17.6 0.4 0.0043 16.7 0.4 1.4 1 0 0 1 1 1 1 RIO1 family Choline_kinase PF01633.20 OQS07476.1 - 0.0049 16.5 0.0 0.011 15.4 0.0 1.6 1 0 0 1 1 1 1 Choline/ethanolamine kinase Kdo PF06293.14 OQS07476.1 - 0.011 15.2 0.1 0.03 13.7 0.0 1.7 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family PHD PF00628.29 OQS07477.1 - 2.8e-07 30.3 2.4 2.8e-07 30.3 2.4 4.1 3 1 1 4 4 4 1 PHD-finger Trm112p PF03966.16 OQS07477.1 - 1.1 9.9 4.5 14 6.4 0.0 3.5 3 0 0 3 3 3 0 Trm112p-like protein Macoilin PF09726.9 OQS07477.1 - 9.4 4.7 26.0 13 4.2 26.0 1.2 1 0 0 1 1 1 0 Macoilin family Roc PF08477.13 OQS07478.1 - 6.6e-10 39.2 0.0 8.9e-10 38.8 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 OQS07478.1 - 4.4e-08 32.9 0.0 5.7e-08 32.5 0.0 1.1 1 0 0 1 1 1 1 Ras family Arf PF00025.21 OQS07478.1 - 0.0016 17.9 0.0 0.0021 17.6 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family DUF868 PF05910.12 OQS07478.1 - 0.032 13.9 0.0 0.037 13.7 0.0 1.1 1 0 0 1 1 1 0 Plant protein of unknown function (DUF868) SLC35F PF06027.12 OQS07479.1 - 1.1e-94 317.4 45.0 4e-49 167.7 17.1 2.1 2 0 0 2 2 2 2 Solute carrier family 35 CRT-like PF08627.10 OQS07479.1 - 1.3e-13 50.6 18.1 2.3e-08 33.4 1.3 4.0 3 2 2 5 5 5 2 CRT-like, chloroquine-resistance transporter-like EamA PF00892.20 OQS07479.1 - 0.00017 21.8 24.9 0.002 18.3 9.5 4.3 4 0 0 4 4 4 2 EamA-like transporter family DUF3185 PF11381.8 OQS07479.1 - 0.029 14.4 0.4 12 6.0 0.0 3.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3185) WD40 PF00400.32 OQS07480.1 - 5.3e-24 84.0 18.3 0.00011 22.9 0.0 6.1 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OQS07480.1 - 1e-06 28.9 4.0 0.13 12.5 0.2 4.4 1 1 4 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Mso1_C PF14477.6 OQS07480.1 - 0.16 12.4 0.3 0.83 10.1 0.0 2.2 2 0 0 2 2 2 0 Membrane-polarising domain of Mso1 SAP PF02037.27 OQS07481.1 - 1.2e-10 40.8 1.7 2.5e-10 39.9 1.7 1.6 1 0 0 1 1 1 1 SAP domain Pinin_SDK_memA PF04696.13 OQS07481.1 - 5.6e-10 39.4 10.7 5.6e-10 39.4 10.7 5.2 2 1 1 3 3 3 1 pinin/SDK/memA/ protein conserved region DUF1664 PF07889.12 OQS07481.1 - 0.0084 16.1 7.9 0.2 11.7 0.7 2.7 2 0 0 2 2 2 2 Protein of unknown function (DUF1664) Ephrin_rec_like PF07699.13 OQS07482.1 - 0.012 15.4 5.6 0.012 15.4 5.6 22.0 5 5 18 23 23 23 0 Putative ephrin-receptor like DUF5305 PF17231.2 OQS07482.1 - 0.039 13.4 0.3 0.064 12.7 0.3 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5305) ECSCR PF15820.5 OQS07482.1 - 0.054 13.3 1.0 0.12 12.2 1.0 1.5 1 0 0 1 1 1 0 Endothelial cell-specific chemotaxis regulator DIM PF08194.12 OQS07482.1 - 0.2 11.9 3.1 1 9.6 0.1 3.8 3 0 0 3 3 3 0 DIM protein RIFIN PF02009.16 OQS07482.1 - 0.27 11.1 0.6 0.43 10.4 0.6 1.2 1 0 0 1 1 1 0 Rifin DUF4083 PF13314.6 OQS07482.1 - 0.52 10.3 1.6 0.88 9.6 1.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4083) Pkinase PF00069.25 OQS07483.1 - 9.7e-52 175.9 0.0 1.1e-51 175.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQS07483.1 - 8.1e-30 104.0 0.0 1.3e-29 103.3 0.0 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OQS07483.1 - 2e-06 27.4 0.0 2.9e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 OQS07483.1 - 0.00052 19.4 0.0 0.00085 18.7 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 OQS07483.1 - 0.00089 18.9 0.0 0.0018 17.9 0.0 1.4 1 0 0 1 1 1 1 RIO1 family Pkinase_fungal PF17667.1 OQS07483.1 - 0.12 11.1 0.0 0.15 10.8 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase Metallophos_C PF14008.6 OQS07484.1 - 6.8e-06 26.9 0.1 1.2e-05 26.1 0.1 1.4 1 0 0 1 1 1 1 Iron/zinc purple acid phosphatase-like protein C Peptidase_M28 PF04389.17 OQS07485.1 - 1.2e-33 116.5 0.0 1.9e-33 115.8 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.28 OQS07485.1 - 2.1e-05 24.3 0.0 8.7e-05 22.3 0.0 1.9 2 0 0 2 2 2 1 Peptidase family M20/M25/M40 Peptidase_M42 PF05343.14 OQS07485.1 - 0.011 14.8 0.0 0.12 11.4 0.0 2.1 1 1 1 2 2 2 0 M42 glutamyl aminopeptidase DUF4910 PF16254.5 OQS07485.1 - 0.028 13.3 0.1 0.079 11.8 0.1 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4910) CPSase_L_D2 PF02786.17 OQS07486.1 - 1.7e-73 246.6 0.1 2.9e-73 245.9 0.1 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 OQS07486.1 - 2.1e-44 150.6 0.2 7.2e-44 148.8 0.1 1.9 2 0 0 2 2 2 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 OQS07486.1 - 9e-37 125.5 0.0 2.5e-36 124.1 0.0 1.8 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.22 OQS07486.1 - 1.2e-16 60.3 1.2 3.4e-16 58.8 1.2 1.8 1 0 0 1 1 1 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.13 OQS07486.1 - 1.8e-12 47.2 0.0 4.1e-12 46.1 0.0 1.5 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 OQS07486.1 - 1.2e-11 44.4 0.0 2.6e-11 43.4 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.14 OQS07486.1 - 5.2e-05 23.3 0.0 0.00012 22.2 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain RimK PF08443.11 OQS07486.1 - 0.00023 20.8 0.0 0.00064 19.4 0.0 1.7 1 1 0 1 1 1 1 RimK-like ATP-grasp domain HlyD_3 PF13437.6 OQS07486.1 - 0.00062 20.4 0.0 0.0095 16.6 0.0 2.6 2 0 0 2 2 2 1 HlyD family secretion protein GARS_A PF01071.19 OQS07486.1 - 0.0026 17.5 0.0 0.0049 16.7 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain Biotin_lipoyl_2 PF13533.6 OQS07486.1 - 0.0058 16.4 0.0 1.6 8.6 0.0 2.7 1 1 1 2 2 2 1 Biotin-lipoyl like ATP-grasp_4 PF13535.6 OQS07486.1 - 0.019 14.6 0.0 0.038 13.6 0.0 1.5 1 0 0 1 1 1 0 ATP-grasp domain HlyD_D23 PF16576.5 OQS07486.1 - 0.028 13.6 0.0 0.69 9.1 0.0 2.4 1 1 1 2 2 2 0 Barrel-sandwich domain of CusB or HlyD membrane-fusion ATPgrasp_ST PF14397.6 OQS07486.1 - 0.072 12.3 0.0 2.1 7.5 0.0 2.2 2 0 0 2 2 2 0 Sugar-transfer associated ATP-grasp GCV_H PF01597.19 OQS07486.1 - 0.21 11.5 0.0 0.45 10.4 0.0 1.4 1 0 0 1 1 1 0 Glycine cleavage H-protein GTP_EFTU PF00009.27 OQS07487.1 - 6.4e-58 195.5 0.0 8.3e-58 195.1 0.0 1.1 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 OQS07487.1 - 7e-29 100.4 0.0 1.3e-28 99.5 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 OQS07487.1 - 7.4e-17 61.5 3.3 1.7e-16 60.4 3.3 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 OQS07487.1 - 3.9e-05 23.7 0.1 8.4e-05 22.6 0.0 1.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase cobW PF02492.19 OQS07487.1 - 0.014 15.0 0.3 0.032 13.8 0.0 1.7 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain RsgA_GTPase PF03193.16 OQS07487.1 - 0.068 13.1 0.1 0.15 11.9 0.0 1.7 2 0 0 2 2 2 0 RsgA GTPase Sugar_tr PF00083.24 OQS07488.1 - 3.6e-46 158.0 19.5 4.4e-46 157.7 19.5 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OQS07488.1 - 2.3e-40 138.6 40.0 3.3e-29 101.9 22.9 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 OQS07488.1 - 1.8e-06 27.5 24.4 0.00012 21.5 10.1 2.2 2 0 0 2 2 2 2 Uncharacterised MFS-type transporter YbfB TRI12 PF06609.13 OQS07488.1 - 0.00025 19.6 3.1 0.00025 19.6 3.1 1.7 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Pkinase_Tyr PF07714.17 OQS07489.1 - 9.8e-112 372.4 0.1 2.2e-55 187.7 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 OQS07489.1 - 4.8e-110 367.1 0.0 7.1e-56 189.5 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_fungal PF17667.1 OQS07489.1 - 9.6e-11 41.1 0.2 6e-05 22.0 0.0 2.2 2 0 0 2 2 2 2 Fungal protein kinase LRR_8 PF13855.6 OQS07489.1 - 5.7e-07 29.2 20.1 0.00026 20.7 1.2 5.8 5 2 1 6 6 6 3 Leucine rich repeat Kdo PF06293.14 OQS07489.1 - 8.6e-05 22.0 0.1 0.011 15.1 0.0 2.3 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 OQS07489.1 - 0.00058 19.3 0.0 0.35 10.1 0.0 2.3 2 0 0 2 2 2 2 Kinase-like APH PF01636.23 OQS07489.1 - 0.0011 19.0 0.1 0.86 9.5 0.0 2.4 2 0 0 2 2 2 2 Phosphotransferase enzyme family Podoplanin PF05808.11 OQS07489.1 - 0.0025 17.9 4.1 0.052 13.7 1.2 2.4 2 0 0 2 2 2 1 Podoplanin LRR_4 PF12799.7 OQS07489.1 - 0.033 14.6 24.7 0.2 12.1 0.9 6.7 6 0 0 6 6 6 0 Leucine Rich repeats (2 copies) Haspin_kinase PF12330.8 OQS07489.1 - 0.037 13.0 0.3 10 5.0 0.0 3.0 3 0 0 3 3 3 0 Haspin like kinase domain DUF4381 PF14316.6 OQS07489.1 - 0.06 13.6 0.5 2.6 8.3 0.6 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) FTA2 PF13095.6 OQS07489.1 - 0.087 12.4 0.1 8.9 5.9 0.0 2.8 3 0 0 3 3 3 0 Kinetochore Sim4 complex subunit FTA2 Phage_holin_2_4 PF16082.5 OQS07489.1 - 0.14 11.9 0.2 0.29 10.9 0.2 1.5 1 0 0 1 1 1 0 Bacteriophage holin family, superfamily II-like Adeno_E3_CR2 PF02439.15 OQS07489.1 - 0.76 9.6 6.5 2.1 8.2 0.3 2.7 2 0 0 2 2 2 0 Adenovirus E3 region protein CR2 DUF2062 PF09835.9 OQS07489.1 - 1.5 8.7 8.8 1.7 8.5 0.4 3.0 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2062) Syndecan PF01034.20 OQS07489.1 - 1.5 8.8 4.7 0.28 11.1 0.2 2.0 2 0 0 2 2 2 0 Syndecan domain MPC PF03650.13 OQS07490.1 - 2e-36 124.5 0.3 2.5e-36 124.2 0.3 1.1 1 0 0 1 1 1 1 Mitochondrial pyruvate carriers CRAL_TRIO PF00650.20 OQS07491.1 - 1.7e-13 50.6 0.0 3.4e-13 49.6 0.0 1.5 1 0 0 1 1 1 1 CRAL/TRIO domain PH PF00169.29 OQS07491.1 - 1.3e-10 41.7 0.0 2.6e-10 40.7 0.0 1.5 1 0 0 1 1 1 1 PH domain CRAL_TRIO_2 PF13716.6 OQS07491.1 - 0.072 13.2 0.0 0.14 12.3 0.0 1.5 1 0 0 1 1 1 0 Divergent CRAL/TRIO domain Pkinase PF00069.25 OQS07492.1 - 2.8e-54 184.2 0.2 9.8e-53 179.2 0.0 2.8 3 0 0 3 3 3 1 Protein kinase domain NGP1NT PF08153.12 OQS07492.1 - 1.4e-45 154.6 0.1 3.1e-45 153.5 0.1 1.6 1 0 0 1 1 1 1 NGP1NT (NUC091) domain Pkinase_Tyr PF07714.17 OQS07492.1 - 2e-30 106.0 0.0 1.6e-29 103.0 0.0 2.2 2 0 0 2 2 2 1 Protein tyrosine kinase MMR_HSR1 PF01926.23 OQS07492.1 - 4.6e-16 58.9 1.5 1e-13 51.4 0.0 2.9 3 0 0 3 3 2 1 50S ribosome-binding GTPase Pkinase_fungal PF17667.1 OQS07492.1 - 8.9e-07 28.0 1.0 2.7e-05 23.2 0.0 2.7 3 0 0 3 3 3 1 Fungal protein kinase zf-rbx1 PF12678.7 OQS07492.1 - 1.1e-05 25.6 5.3 3.7e-05 23.9 5.3 1.9 1 0 0 1 1 1 1 RING-H2 zinc finger domain FeoB_N PF02421.18 OQS07492.1 - 1.8e-05 24.3 0.1 0.0002 20.9 0.0 2.4 2 0 0 2 2 2 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 OQS07492.1 - 4.3e-05 23.5 0.5 0.00014 21.8 0.0 2.0 2 1 0 2 2 2 1 RsgA GTPase zf-RING_2 PF13639.6 OQS07492.1 - 0.0003 21.1 9.9 0.00068 19.9 9.9 1.7 1 0 0 1 1 1 1 Ring finger domain zf-ANAPC11 PF12861.7 OQS07492.1 - 0.0016 18.4 6.3 0.0044 17.1 6.3 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_2 PF13923.6 OQS07492.1 - 0.0033 17.2 8.5 0.01 15.7 8.5 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) GTP_EFTU PF00009.27 OQS07492.1 - 0.013 15.0 0.1 0.33 10.5 0.1 2.7 1 1 1 3 3 3 0 Elongation factor Tu GTP binding domain RIO1 PF01163.22 OQS07492.1 - 0.021 14.4 0.0 0.11 12.1 0.0 2.2 2 0 0 2 2 2 0 RIO1 family Dynamin_N PF00350.23 OQS07492.1 - 0.029 14.4 0.4 0.41 10.7 0.0 2.8 2 1 1 3 3 3 0 Dynamin family MMR_HSR1_Xtn PF16897.5 OQS07492.1 - 0.05 13.6 1.0 2 8.5 0.0 2.6 2 0 0 2 2 2 0 C-terminal region of MMR_HSR1 domain AAA_18 PF13238.6 OQS07492.1 - 0.052 14.1 0.5 0.41 11.2 0.0 2.8 2 1 1 3 3 3 0 AAA domain zf-RING_11 PF17123.5 OQS07492.1 - 0.074 12.8 4.0 0.24 11.2 4.0 2.0 1 0 0 1 1 1 0 RING-like zinc finger Arf PF00025.21 OQS07492.1 - 0.085 12.3 0.1 2 7.8 0.0 2.6 2 0 0 2 2 2 0 ADP-ribosylation factor family zinc_ribbon_16 PF17034.5 OQS07492.1 - 0.51 10.6 5.4 1.4 9.2 5.4 1.8 1 0 0 1 1 1 0 Zinc-ribbon like family zf-RING_5 PF14634.6 OQS07492.1 - 0.66 10.0 8.9 1.4 8.9 8.9 1.6 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4 PF00097.25 OQS07492.1 - 0.69 9.8 8.2 1.7 8.6 8.2 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 OQS07492.1 - 0.94 9.4 6.6 1.8 8.5 6.6 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 OQS07492.1 - 1.7 8.4 8.2 3.8 7.2 8.2 1.5 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type S1 PF00575.23 OQS07493.1 - 5.3e-65 215.7 10.4 2.7e-10 40.5 0.1 11.6 12 0 0 12 12 12 8 S1 RNA binding domain Suf PF05843.14 OQS07493.1 - 1e-07 32.2 0.7 1e-07 32.2 0.7 3.7 3 1 1 4 4 4 2 Suppressor of forked protein (Suf) TPR_15 PF13429.6 OQS07493.1 - 5e-05 22.7 2.3 6e-05 22.4 0.2 1.9 1 1 1 2 2 2 1 Tetratricopeptide repeat Nop14 PF04147.12 OQS07493.1 - 0.0045 15.3 29.3 0.0083 14.4 29.3 1.3 1 0 0 1 1 1 1 Nop14-like family TPR_19 PF14559.6 OQS07493.1 - 0.059 13.9 0.0 0.29 11.7 0.0 2.2 3 0 0 3 3 3 0 Tetratricopeptide repeat Pep_M12B_propep PF01562.19 OQS07493.1 - 0.095 12.9 0.1 8.1 6.7 0.0 3.8 4 0 0 4 4 4 0 Reprolysin family propeptide HSP70 PF00012.20 OQS07494.1 - 4.3e-26 91.3 9.8 4.3e-26 91.3 9.8 3.1 2 1 0 2 2 2 1 Hsp70 protein PagL PF09411.10 OQS07494.1 - 0.14 12.3 0.0 0.3 11.2 0.0 1.4 1 0 0 1 1 1 0 Lipid A 3-O-deacylase (PagL) V_ATPase_I PF01496.19 OQS07494.1 - 6.3 4.6 15.8 0.48 8.3 6.8 2.1 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family PH PF00169.29 OQS07495.1 - 6.4e-14 52.3 0.0 8.5e-14 51.9 0.0 1.2 1 0 0 1 1 1 1 PH domain PH_9 PF15410.6 OQS07495.1 - 0.0088 16.4 0.1 0.3 11.5 0.1 2.2 1 1 0 1 1 1 1 Pleckstrin homology domain PH_4 PF15404.6 OQS07495.1 - 0.02 14.7 0.4 0.43 10.4 0.0 2.2 1 1 1 2 2 2 0 Pleckstrin homology domain DPBB_1 PF03330.18 OQS07496.1 - 2.4e-14 53.4 5.4 0.00062 20.0 0.1 3.6 3 0 0 3 3 3 3 Lytic transglycolase NAD_binding_2 PF03446.15 OQS07496.1 - 0.00044 20.5 0.0 7.4 6.7 0.0 3.8 3 0 0 3 3 3 2 NAD binding domain of 6-phosphogluconate dehydrogenase Amnionless PF14828.6 OQS07496.1 - 0.029 13.2 4.2 0.45 9.3 0.1 2.7 3 0 0 3 3 3 0 Amnionless EphA2_TM PF14575.6 OQS07496.1 - 0.05 14.5 0.2 1.4 9.8 0.1 2.4 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain ACT_7 PF13840.6 OQS07496.1 - 0.063 13.1 0.4 4.6 7.1 0.0 2.4 2 0 0 2 2 2 0 ACT domain DUF681 PF05080.12 OQS07496.1 - 0.097 13.3 0.0 68 4.2 0.0 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF681) DUF5305 PF17231.2 OQS07496.1 - 0.22 10.9 3.4 9.4 5.6 0.0 3.3 4 0 0 4 4 4 0 Family of unknown function (DUF5305) EF-hand_1 PF00036.32 OQS07497.1 - 4.2e-16 57.2 0.4 1.2e-06 27.7 0.2 2.7 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 OQS07497.1 - 3.4e-12 45.3 0.4 3.4e-05 23.4 0.0 2.8 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 OQS07497.1 - 5e-12 44.7 0.8 2.5e-05 23.5 0.0 2.7 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 OQS07497.1 - 1.5e-10 41.3 0.0 1.5e-10 41.3 0.0 2.7 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_8 PF13833.6 OQS07497.1 - 2.9e-07 30.2 0.3 0.0095 15.8 0.0 2.9 2 0 0 2 2 2 2 EF-hand domain pair Chibby PF14645.6 OQS07497.1 - 0.0022 18.4 0.9 0.0078 16.6 0.9 1.9 1 0 0 1 1 1 1 Chibby family APG6_N PF17675.1 OQS07497.1 - 0.014 15.9 5.3 0.014 15.9 5.3 2.5 3 0 0 3 3 3 0 Apg6 coiled-coil region Mago-bind PF09282.10 OQS07498.1 - 1.8e-25 88.4 11.4 4.1e-13 48.9 2.9 2.4 2 0 0 2 2 2 2 Mago binding PH PF00169.29 OQS07500.1 - 8e-10 39.2 0.1 2.1e-09 37.9 0.1 1.7 1 0 0 1 1 1 1 PH domain PH_3 PF14593.6 OQS07500.1 - 7.1e-08 32.5 0.0 1.8e-07 31.2 0.0 1.6 1 0 0 1 1 1 1 PH domain PH_8 PF15409.6 OQS07500.1 - 0.00012 22.3 0.1 0.00035 20.8 0.1 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain PH_11 PF15413.6 OQS07500.1 - 0.032 14.6 1.8 0.63 10.5 1.8 2.8 1 1 0 1 1 1 0 Pleckstrin homology domain DNTTIP1_dimer PF18192.1 OQS07500.1 - 0.069 13.5 0.2 0.21 12.0 0.2 1.7 1 0 0 1 1 1 0 DNTTIP1 dimerisation domain DPBB_1 PF03330.18 OQS07501.1 - 4.1e-08 33.4 0.2 1.1e-07 32.0 0.1 1.8 1 1 0 1 1 1 1 Lytic transglycolase Barwin PF00967.17 OQS07501.1 - 0.0022 17.8 0.5 0.0039 17.0 0.5 1.3 1 0 0 1 1 1 1 Barwin family DUF681 PF05080.12 OQS07501.1 - 0.11 13.1 0.4 9.9 6.9 0.1 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF681) TFIIA PF03153.13 OQS07501.1 - 0.89 9.5 8.7 1.3 9.0 8.7 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Rhodanese PF00581.20 OQS07503.1 - 0.005 17.3 0.1 0.0064 17.0 0.1 1.2 1 0 0 1 1 1 1 Rhodanese-like domain PTCB-BRCT PF12738.7 OQS07504.1 - 8.6e-28 96.1 2.5 1.7e-09 37.5 0.0 5.9 5 1 0 5 5 5 4 twin BRCT domain BRCT PF00533.26 OQS07504.1 - 1.8e-27 95.5 0.8 5.4e-07 29.9 0.0 6.4 7 0 0 7 7 7 4 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 OQS07504.1 - 2.7e-25 88.6 0.0 0.00087 19.7 0.0 7.2 6 1 0 6 6 6 5 BRCT domain, a BRCA1 C-terminus domain RTT107_BRCT_5 PF16770.5 OQS07504.1 - 1.4e-09 37.7 0.4 3.3e-06 26.9 0.0 4.5 5 0 0 5 5 5 1 Regulator of Ty1 transposition protein 107 BRCT domain S_2TMBeta PF18153.1 OQS07505.1 - 0.21 11.3 0.1 0.21 11.3 0.1 1.7 2 0 0 2 2 2 0 SMODS-associating 2TM, beta-strand rich effector domain DUF3671 PF12420.8 OQS07505.1 - 9.4 6.3 8.2 51 4.0 0.3 3.8 3 1 0 3 3 3 0 Protein of unknown function P-II PF00543.22 OQS07506.1 - 0.039 14.6 2.7 0.048 14.3 1.6 1.6 1 1 1 2 2 2 0 Nitrogen regulatory protein P-II Peptidase_C58 PF03543.14 OQS07506.1 - 0.85 9.3 5.5 1.1 8.9 5.5 1.3 1 0 0 1 1 1 0 Yersinia/Haemophilus virulence surface antigen CPSase_L_D3 PF02787.19 OQS07506.1 - 1.1 9.6 5.1 1.4 9.3 1.9 2.1 1 1 1 2 2 2 0 Carbamoyl-phosphate synthetase large chain, oligomerisation domain WD40 PF00400.32 OQS07507.1 - 0.075 13.9 0.1 8.8 7.4 0.0 3.8 4 0 0 4 4 4 0 WD domain, G-beta repeat RICTOR_N PF14664.6 OQS07508.1 - 8.8e-83 278.3 3.3 1.5e-82 277.6 3.3 1.4 1 0 0 1 1 1 1 Rapamycin-insensitive companion of mTOR, N-term RICTOR_V PF14668.6 OQS07508.1 - 8.7e-26 90.0 3.2 2.1e-23 82.3 0.5 3.7 4 0 0 4 4 4 1 Rapamycin-insensitive companion of mTOR, domain 5 RICTOR_M PF14666.6 OQS07508.1 - 6.4e-24 83.7 3.9 7.9e-24 83.4 0.2 3.3 4 0 0 4 4 4 1 Rapamycin-insensitive companion of mTOR, middle domain RasGEF_N_2 PF14663.6 OQS07508.1 - 1.2e-19 70.7 0.7 7.5e-19 68.1 0.2 2.8 2 0 0 2 2 2 1 Rapamycin-insensitive companion of mTOR RasGEF_N domain HEAT_EZ PF13513.6 OQS07508.1 - 0.023 15.2 0.1 0.53 10.9 0.0 3.3 2 0 0 2 2 2 0 HEAT-like repeat Adaptin_N PF01602.20 OQS07508.1 - 0.05 12.2 5.2 1.3 7.4 1.1 3.7 4 1 0 4 4 4 0 Adaptin N terminal region Arm PF00514.23 OQS07508.1 - 0.37 10.9 10.4 1.3e+02 2.8 0.0 6.8 7 0 0 7 7 7 0 Armadillo/beta-catenin-like repeat HEAT PF02985.22 OQS07508.1 - 0.4 11.1 3.8 1.7e+02 2.9 0.0 4.5 4 0 0 4 4 4 0 HEAT repeat DUF3678 PF12435.8 OQS07508.1 - 0.71 9.3 7.7 24 4.4 6.2 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3678) CPBP PF02517.16 OQS07509.1 - 3.7e-10 40.0 7.8 3.7e-10 40.0 7.8 2.1 2 1 0 2 2 2 1 CPBP intramembrane metalloprotease NUFIP1 PF10453.9 OQS07511.1 - 3.2e-13 49.3 3.3 7.3e-13 48.1 3.3 1.6 1 0 0 1 1 1 1 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) zf-CCCH PF00642.24 OQS07511.1 - 1.2e-09 37.8 13.8 2e-07 30.8 2.8 3.2 3 0 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCHC_2 PF13696.6 OQS07511.1 - 1.7e-08 34.1 1.6 3.8e-08 33.0 1.6 1.6 1 0 0 1 1 1 1 Zinc knuckle zf_CCCH_4 PF18345.1 OQS07511.1 - 2.5e-08 33.7 13.1 9.6e-06 25.5 4.4 2.6 2 0 0 2 2 2 2 Zinc finger domain Torus PF16131.5 OQS07511.1 - 2.2e-05 25.1 8.2 0.018 15.8 2.7 2.8 1 1 1 2 2 2 2 Torus domain zf-CCCH_4 PF18044.1 OQS07511.1 - 0.00075 19.2 2.4 0.00075 19.2 2.4 3.0 3 0 0 3 3 3 1 CCCH-type zinc finger zf-met PF12874.7 OQS07511.1 - 0.0022 18.3 1.2 0.0022 18.3 1.2 2.3 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 OQS07511.1 - 0.0039 17.4 2.9 0.014 15.7 2.9 2.1 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-CCHC PF00098.23 OQS07511.1 - 0.0043 17.1 1.0 0.012 15.6 1.0 1.8 1 0 0 1 1 1 1 Zinc knuckle EF-hand_7 PF13499.6 OQS07511.1 - 0.0083 16.6 0.7 0.46 11.0 0.2 2.4 2 0 0 2 2 2 1 EF-hand domain pair zf-CCHC_3 PF13917.6 OQS07511.1 - 0.0087 16.0 2.5 0.02 14.8 2.5 1.6 1 0 0 1 1 1 1 Zinc knuckle EF-hand_8 PF13833.6 OQS07511.1 - 0.012 15.4 0.4 0.55 10.1 0.1 2.5 2 0 0 2 2 2 0 EF-hand domain pair EF-hand_6 PF13405.6 OQS07511.1 - 0.018 14.9 0.3 12 6.1 0.1 3.3 3 0 0 3 3 3 0 EF-hand domain zf-CCCH_2 PF14608.6 OQS07511.1 - 0.28 11.7 14.1 2.5 8.7 3.8 2.9 2 0 0 2 2 2 0 RNA-binding, Nab2-type zinc finger Hexapep PF00132.24 OQS07512.1 - 3.3e-10 39.3 7.8 1.1e-07 31.2 3.5 3.3 3 0 0 3 3 3 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 OQS07512.1 - 2 8.2 12.8 2.8 7.8 5.3 3.7 4 1 1 5 5 5 0 Hexapeptide repeat of succinyl-transferase LRR_6 PF13516.6 OQS07516.1 - 2e-07 30.5 1.3 0.031 14.3 0.0 4.5 5 0 0 5 5 5 2 Leucine Rich repeat KIX_2 PF16987.5 OQS07516.1 - 0.0054 16.7 0.0 0.011 15.6 0.0 1.6 1 0 0 1 1 1 1 KIX domain LRR_4 PF12799.7 OQS07516.1 - 0.022 15.2 8.2 0.28 11.7 0.3 5.0 2 1 5 7 7 7 0 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 OQS07516.1 - 0.085 13.5 2.2 45 5.1 0.0 5.6 6 0 0 6 6 6 0 Leucine Rich Repeat DUF1986 PF09342.11 OQS07516.1 - 0.16 12.4 0.0 11 6.4 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1986) LRR_8 PF13855.6 OQS07516.1 - 1.7 8.5 12.4 14 5.5 0.0 5.7 6 1 0 6 6 6 0 Leucine rich repeat RasGAP PF00616.19 OQS07517.1 - 3.4e-11 43.3 1.4 2.1e-08 34.1 0.0 3.2 3 1 1 4 4 4 2 GTPase-activator protein for Ras-like GTPase APG6_N PF17675.1 OQS07517.1 - 0.0034 17.9 17.3 0.018 15.6 8.0 3.3 3 0 0 3 3 3 2 Apg6 coiled-coil region Thiol_cytolysin PF01289.19 OQS07517.1 - 0.02 13.8 0.0 0.041 12.8 0.0 1.4 1 0 0 1 1 1 0 Thiol-activated cytolysin FlxA PF14282.6 OQS07517.1 - 7.3 6.6 13.2 25 4.9 13.2 1.9 1 0 0 1 1 1 0 FlxA-like protein CSRNP_N PF16019.5 OQS07519.1 - 1.4e-09 38.2 13.5 9.2e-05 22.5 1.7 3.4 2 2 0 2 2 2 2 Cysteine/serine-rich nuclear protein N-terminus DUF2322 PF10084.9 OQS07519.1 - 0.0039 17.2 0.0 1.9 8.6 0.0 2.7 3 0 0 3 3 3 2 Uncharacterized protein conserved in bacteria (DUF2322) DUF2757 PF10955.8 OQS07519.1 - 0.25 11.6 2.1 0.69 10.2 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2757) Epimerase PF01370.21 OQS07520.1 - 2.6e-48 164.6 0.0 4.1e-48 164.0 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 OQS07520.1 - 2.3e-11 43.7 0.0 7.3e-11 42.0 0.0 1.7 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 OQS07520.1 - 5.2e-05 22.5 0.0 9.3e-05 21.7 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain RRM_1 PF00076.22 OQS07521.1 - 1.6e-23 82.2 0.0 1.2e-12 47.5 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 OQS07521.1 - 7.1e-13 48.2 0.0 3.8e-05 23.3 0.0 2.1 1 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 OQS07521.1 - 2e-12 46.8 0.0 3.9e-07 29.8 0.0 2.1 2 0 0 2 2 2 2 Occluded RNA-recognition motif Limkain-b1 PF11608.8 OQS07521.1 - 0.05 13.7 0.0 0.18 11.9 0.0 1.9 2 0 0 2 2 2 0 Limkain b1 CSRNP_N PF16019.5 OQS07522.1 - 5.3e-10 39.6 0.2 0.00029 20.8 0.0 2.7 2 1 0 2 2 2 2 Cysteine/serine-rich nuclear protein N-terminus Peptidase_C1 PF00112.23 OQS07524.1 - 1.9e-10 41.2 2.6 1.3e-09 38.5 1.9 2.0 2 0 0 2 2 2 1 Papain family cysteine protease Peptidase_C1_2 PF03051.15 OQS07524.1 - 0.03 13.1 0.2 0.032 13.0 0.2 1.1 1 0 0 1 1 1 0 Peptidase C1-like family Ank_2 PF12796.7 OQS07525.1 - 1e-12 48.4 2.4 2.7e-08 34.3 0.7 3.2 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQS07525.1 - 1e-11 45.1 2.6 6.5e-05 23.4 0.2 5.0 4 2 0 4 4 4 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 OQS07525.1 - 5e-11 42.6 3.1 0.17 12.2 0.3 5.6 3 2 2 5 5 5 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQS07525.1 - 1.1e-08 34.6 3.1 20 6.2 0.0 6.9 6 1 1 7 7 7 1 Ankyrin repeat DUF3817 PF12823.7 OQS07525.1 - 0.0028 18.5 0.4 0.054 14.3 0.1 2.9 2 1 1 3 3 3 1 Domain of unknown function (DUF3817) DUF3447 PF11929.8 OQS07525.1 - 0.0079 16.1 0.9 0.088 12.8 0.0 2.9 2 2 0 2 2 2 1 Domain of unknown function (DUF3447) HeH PF12949.7 OQS07525.1 - 0.0094 15.6 0.0 0.035 13.8 0.0 1.9 2 0 0 2 2 2 1 HeH/LEM domain Adenylsucc_synt PF00709.21 OQS07525.1 - 0.024 13.6 0.0 0.037 13.0 0.0 1.2 1 0 0 1 1 1 0 Adenylosuccinate synthetase Ank PF00023.30 OQS07525.1 - 0.21 12.1 2.5 59 4.4 0.3 4.4 2 2 1 3 3 3 0 Ankyrin repeat BSMAP PF12280.8 OQS07526.1 - 0.035 14.3 0.0 0.042 14.1 0.0 1.1 1 0 0 1 1 1 0 Brain specific membrane anchored protein SAP130_C PF16014.5 OQS07526.1 - 0.12 11.5 3.7 0.17 10.9 3.7 1.2 1 0 0 1 1 1 0 Histone deacetylase complex subunit SAP130 C-terminus Baculo_helicase PF04735.12 OQS07526.1 - 0.14 9.6 0.0 0.18 9.3 0.0 1.0 1 0 0 1 1 1 0 Baculovirus DNA helicase ABC_membrane PF00664.23 OQS07527.1 - 3.2e-20 72.9 12.6 3.2e-20 72.9 12.6 2.5 3 0 0 3 3 3 1 ABC transporter transmembrane region ABC_tran PF00005.27 OQS07527.1 - 6.1e-11 43.0 0.0 1.3e-10 41.9 0.0 1.5 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 OQS07527.1 - 3.3e-05 23.5 0.0 5.2e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain LRR_4 PF12799.7 OQS07528.1 - 1.4e-07 31.6 8.3 0.00019 21.7 0.3 4.0 3 1 1 4 4 4 3 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 OQS07528.1 - 1.8e-07 30.6 9.9 1.4 9.1 0.0 6.2 6 0 0 6 6 6 4 Leucine Rich repeat LRR_1 PF00560.33 OQS07528.1 - 7.6e-06 25.8 6.1 7.1 7.6 0.1 6.8 6 0 0 6 6 6 2 Leucine Rich Repeat LRR_8 PF13855.6 OQS07528.1 - 0.064 13.0 15.9 0.08 12.7 2.4 5.7 5 1 0 6 6 6 0 Leucine rich repeat PITH PF06201.13 OQS07529.1 - 0.015 15.5 1.9 0.13 12.5 1.1 2.5 1 1 1 2 2 2 0 PITH domain LRR_6 PF13516.6 OQS07529.1 - 0.02 14.9 0.1 0.02 14.9 0.1 6.4 8 0 0 8 8 8 0 Leucine Rich repeat Ank_2 PF12796.7 OQS07530.1 - 5.8e-10 39.6 0.1 2.8e-08 34.2 0.1 2.2 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 OQS07530.1 - 7.7e-08 32.4 0.5 0.002 18.5 0.0 3.0 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.6 OQS07530.1 - 7e-06 26.0 0.2 0.16 12.6 0.0 3.1 1 1 2 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 OQS07530.1 - 0.0017 18.6 0.0 0.49 10.8 0.0 2.2 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 OQS07530.1 - 0.0017 18.9 0.0 0.41 11.3 0.0 2.2 2 0 0 2 2 2 2 Ankyrin repeats (many copies) HIRAN PF08797.11 OQS07530.1 - 0.007 16.3 0.0 0.0082 16.1 0.0 1.1 1 0 0 1 1 1 1 HIRAN domain DBD_Tnp_Hermes PF10683.9 OQS07530.1 - 0.048 13.3 0.0 4.8 6.9 0.0 2.1 2 0 0 2 2 2 0 Hermes transposase DNA-binding domain LRR_6 PF13516.6 OQS07531.1 - 2.5e-19 67.6 21.3 4.2e-05 23.2 0.4 7.3 7 0 0 7 7 7 5 Leucine Rich repeat LRR_4 PF12799.7 OQS07531.1 - 7.9e-06 26.1 23.1 1.5 9.3 5.3 5.8 3 1 2 5 5 5 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 OQS07531.1 - 0.01 15.6 28.7 6.4 6.6 6.3 6.1 4 3 0 4 4 4 0 Leucine rich repeat LRR_1 PF00560.33 OQS07531.1 - 0.014 15.8 13.5 30 5.7 0.2 6.8 7 0 0 7 7 7 0 Leucine Rich Repeat Ank_4 PF13637.6 OQS07532.1 - 4.5e-20 71.7 2.2 1.6e-08 34.9 0.0 3.9 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 OQS07532.1 - 4.4e-19 68.8 4.9 1e-09 38.8 0.5 2.6 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OQS07532.1 - 1.1e-16 59.2 4.9 0.00099 19.4 0.1 5.1 4 1 1 5 5 5 4 Ankyrin repeat Ank_5 PF13857.6 OQS07532.1 - 3e-15 56.1 2.8 3.6e-05 23.9 0.1 4.6 2 2 3 5 5 5 3 Ankyrin repeats (many copies) Ank PF00023.30 OQS07532.1 - 3e-15 55.9 11.9 0.0019 18.6 0.2 5.1 4 1 1 5 5 5 5 Ankyrin repeat Mic1 PF07035.12 OQS07532.1 - 0.05 13.3 0.9 0.59 9.8 0.1 2.7 2 1 1 3 3 3 0 Colon cancer-associated protein Mic1-like tRNA_int_endo PF01974.17 OQS07533.1 - 6.8e-18 64.5 0.1 1.3e-17 63.6 0.1 1.4 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain Glycos_transf_2 PF00535.26 OQS07533.1 - 0.11 12.3 0.0 0.23 11.2 0.0 1.5 1 0 0 1 1 1 0 Glycosyl transferase family 2 ABC_tran PF00005.27 OQS07534.1 - 1.5e-27 96.8 0.0 3.9e-15 56.6 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 OQS07534.1 - 1e-10 41.8 9.7 1e-10 41.8 9.7 2.4 2 0 0 2 2 2 2 ABC transporter transmembrane region UCH PF00443.29 OQS07536.1 - 3.2e-41 141.5 4.8 4.5e-41 141.0 4.8 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 OQS07536.1 - 2.6e-12 47.0 10.3 3.8e-12 46.5 10.3 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Ank_2 PF12796.7 OQS07537.1 - 6e-13 49.2 0.0 2.3e-07 31.3 0.0 2.3 2 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 OQS07537.1 - 3e-12 46.4 0.1 1.5e-07 31.5 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.6 OQS07537.1 - 8.3e-12 44.2 0.0 1.5e-05 25.0 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.6 OQS07537.1 - 1.2e-10 41.4 0.1 2.9e-06 27.4 0.0 2.4 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 OQS07537.1 - 1.3e-09 38.4 0.0 2.2e-05 24.9 0.0 2.4 2 0 0 2 2 2 2 Ankyrin repeats (many copies) DUF1699 PF08004.11 OQS07537.1 - 0.081 12.6 0.1 0.24 11.1 0.0 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1699) HECT PF00632.25 OQS07538.1 - 1.1e-53 182.8 0.0 2.1e-53 181.8 0.0 1.4 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) MIB_HERC2 PF06701.13 OQS07538.1 - 3e-20 72.2 5.2 6.5e-20 71.2 5.2 1.6 1 0 0 1 1 1 1 Mib_herc2 ZZ PF00569.17 OQS07538.1 - 5.8e-09 35.6 9.2 5.8e-09 35.6 9.2 4.0 3 0 0 3 3 3 2 Zinc finger, ZZ type zf-RanBP PF00641.18 OQS07538.1 - 0.00086 18.6 6.7 0.00086 18.6 6.7 4.7 4 0 0 4 4 4 2 Zn-finger in Ran binding protein and others LRR_4 PF12799.7 OQS07538.1 - 0.0098 16.3 3.6 5.1 7.7 0.0 4.2 2 1 1 3 3 3 2 Leucine Rich repeats (2 copies) PDZ PF00595.24 OQS07539.1 - 9.4e-19 67.6 0.0 0.00089 19.6 0.0 5.4 5 0 0 5 5 5 5 PDZ domain PDZ_6 PF17820.1 OQS07539.1 - 1.5e-15 56.7 0.0 0.056 13.3 0.0 5.6 5 0 0 5 5 5 5 PDZ domain zf-MYND PF01753.18 OQS07539.1 - 4.6e-07 29.8 9.8 8.5e-07 29.0 9.8 1.5 1 0 0 1 1 1 1 MYND finger zf-Mss51 PF13824.6 OQS07539.1 - 0.019 15.1 2.4 0.056 13.5 2.4 1.8 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 CopC PF04234.12 OQS07539.1 - 0.035 15.2 2.0 0.59 11.2 0.1 3.6 4 0 0 4 4 4 0 CopC domain PDZ_2 PF13180.6 OQS07539.1 - 0.04 14.3 0.5 13 6.2 0.0 4.1 5 0 0 5 5 5 0 PDZ domain Pex16 PF08610.10 OQS07540.1 - 4e-58 197.1 0.0 5e-58 196.8 0.0 1.0 1 0 0 1 1 1 1 Peroxisomal membrane protein (Pex16) PQ-loop PF04193.14 OQS07541.1 - 1.1e-25 89.2 3.6 1.9e-14 53.2 0.1 2.5 2 0 0 2 2 2 2 PQ loop repeat ER_lumen_recept PF00810.18 OQS07541.1 - 0.002 18.9 5.9 0.0035 18.2 4.6 2.0 1 1 1 2 2 2 1 ER lumen protein retaining receptor DUF1430 PF07242.11 OQS07541.1 - 0.064 13.5 0.4 0.064 13.5 0.4 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1430) MtN3_slv PF03083.16 OQS07541.1 - 0.58 10.2 6.5 0.46 10.5 0.2 3.0 2 1 2 4 4 4 0 Sugar efflux transporter for intercellular exchange Ferlin_C PF16165.5 OQS07541.1 - 5.2 7.0 7.5 5.4 6.9 5.0 2.0 1 1 1 2 2 2 0 Ferlin C-terminus YlaH PF14036.6 OQS07541.1 - 9.6 6.6 10.5 6.4 7.2 0.4 2.9 3 0 0 3 3 3 0 YlaH-like protein cNMP_binding PF00027.29 OQS07542.1 - 6.6e-31 106.2 0.0 5.3e-16 58.5 0.0 2.6 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain TLC PF03219.14 OQS07542.1 - 0.0073 15.1 4.5 0.24 10.1 0.7 2.4 2 0 0 2 2 2 2 TLC ATP/ADP transporter Myb_DNA-binding PF00249.31 OQS07543.1 - 5.1e-68 225.0 19.9 1.9e-14 53.5 0.8 5.5 5 0 0 5 5 5 5 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OQS07543.1 - 2.7e-56 187.7 11.7 4.4e-16 58.9 0.2 5.6 2 2 3 5 5 5 5 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OQS07543.1 - 1.9e-06 27.6 0.1 0.67 9.9 0.0 4.5 3 1 1 4 4 4 2 Myb DNA-binding like Spore_III_AB PF09548.10 OQS07543.1 - 2.9e-06 27.5 3.1 0.2 11.8 0.1 3.5 3 0 0 3 3 3 2 Stage III sporulation protein AB (spore_III_AB) Rap1_C PF11626.8 OQS07543.1 - 5.5e-05 23.2 1.1 0.24 11.5 0.1 3.9 2 1 0 2 2 2 2 TRF2-interacting telomeric protein/Rap1 - C terminal domain SLIDE PF09111.10 OQS07543.1 - 0.001 19.1 0.2 9.2 6.3 0.0 4.3 3 2 1 4 4 4 1 SLIDE Myb_DNA-bind_4 PF13837.6 OQS07543.1 - 0.0099 16.2 15.3 0.36 11.2 0.1 5.4 6 1 0 6 6 6 2 Myb/SANT-like DNA-binding domain Peptidase_M75 PF09375.10 OQS07543.1 - 0.11 11.9 0.2 0.24 10.8 0.2 1.5 1 0 0 1 1 1 0 Imelysin PriCT_2 PF08707.11 OQS07543.1 - 10 6.6 7.9 51 4.3 0.0 4.4 3 2 2 5 5 5 0 Primase C terminal 2 (PriCT-2) SPRY PF00622.28 OQS07544.1 - 1.7e-09 37.8 0.1 0.002 18.2 0.0 2.3 2 0 0 2 2 2 2 SPRY domain Neuralized PF07177.12 OQS07544.1 - 0.13 12.3 0.0 0.2 11.6 0.0 1.3 1 0 0 1 1 1 0 Neuralized NDK PF00334.19 OQS07545.1 - 4.5e-52 175.6 0.0 6e-52 175.2 0.0 1.2 1 0 0 1 1 1 1 Nucleoside diphosphate kinase Trypsin PF00089.26 OQS07547.1 - 0.00027 20.8 0.8 0.00033 20.5 0.8 1.2 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 OQS07547.1 - 0.0013 19.7 0.3 0.0015 19.4 0.3 1.2 1 0 0 1 1 1 1 Trypsin-like peptidase domain Peptidase_S46 PF10459.9 OQS07547.1 - 0.023 13.4 0.0 0.024 13.3 0.0 1.0 1 0 0 1 1 1 0 Peptidase S46 SfsA PF03749.13 OQS07548.1 - 3.6e-37 127.3 0.9 5.2e-37 126.8 0.5 1.4 2 0 0 2 2 2 1 Sugar fermentation stimulation protein RE domain SfsA_N PF17746.1 OQS07548.1 - 3.5e-19 68.7 0.0 6.9e-19 67.8 0.0 1.5 1 0 0 1 1 1 1 SfsA N-terminal OB domain NOG1_N PF17835.1 OQS07548.1 - 0.048 13.6 0.1 0.097 12.6 0.1 1.5 1 0 0 1 1 1 0 NOG1 N-terminal helical domain PDDEXK_9 PF08011.11 OQS07548.1 - 0.069 13.1 0.3 0.069 13.1 0.3 1.6 2 0 0 2 2 2 0 PD-(D/E)XK nuclease superfamily LpxK PF02606.14 OQS07549.1 - 6.8e-56 189.7 0.0 4.4e-36 124.6 0.0 2.0 1 1 1 2 2 2 2 Tetraacyldisaccharide-1-P 4'-kinase Ectoine_synth PF06339.12 OQS07550.1 - 6.1e-26 91.1 0.1 7.4e-26 90.8 0.1 1.1 1 0 0 1 1 1 1 Ectoine synthase Cupin_2 PF07883.11 OQS07550.1 - 3.5e-06 26.6 0.5 7.2e-06 25.6 0.5 1.5 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.19 OQS07550.1 - 0.056 13.4 0.2 0.074 13.0 0.2 1.3 1 0 0 1 1 1 0 AraC-like ligand binding domain Pirin_C PF05726.13 OQS07550.1 - 0.08 13.3 0.0 0.12 12.8 0.0 1.3 1 0 0 1 1 1 0 Pirin C-terminal cupin domain HOOK PF05622.12 OQS07551.1 - 8.3e-55 186.2 50.1 1.4e-54 185.5 50.1 1.2 1 0 0 1 1 1 1 HOOK protein CH PF00307.31 OQS07551.1 - 0.013 15.7 0.0 0.069 13.3 0.0 2.3 1 0 0 1 1 1 0 Calponin homology (CH) domain DMPK_coil PF08826.10 OQS07551.1 - 0.017 15.2 2.0 0.017 15.2 2.0 6.0 5 2 2 7 7 7 0 DMPK coiled coil domain like HALZ PF02183.18 OQS07551.1 - 0.062 13.5 0.1 0.062 13.5 0.1 6.8 7 0 0 7 7 7 0 Homeobox associated leucine zipper MCM_N PF14551.6 OQS07551.1 - 1.9 9.1 17.2 1.2 9.7 2.7 4.6 4 2 0 5 5 5 0 MCM N-terminal domain Arm PF00514.23 OQS07552.1 - 1.5e-42 142.4 13.2 1.5e-08 34.4 0.1 6.0 6 0 0 6 6 6 5 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 OQS07552.1 - 1.1e-16 61.0 14.0 4.3e-09 36.6 0.6 4.1 2 2 2 4 4 4 4 HEAT repeats KAP PF05804.12 OQS07552.1 - 3.1e-10 38.9 0.9 1.9e-06 26.4 0.3 2.1 1 1 1 2 2 2 2 Kinesin-associated protein (KAP) Arm_2 PF04826.13 OQS07552.1 - 6.5e-09 35.6 9.7 5.7e-05 22.7 6.7 3.3 1 1 2 3 3 3 3 Armadillo-like HEAT_EZ PF13513.6 OQS07552.1 - 6.7e-06 26.5 11.8 0.22 12.1 0.5 4.2 4 0 0 4 4 4 3 HEAT-like repeat HEAT PF02985.22 OQS07552.1 - 6.8e-06 25.9 9.0 0.45 10.9 0.0 5.1 5 0 0 5 5 5 2 HEAT repeat Arm_3 PF16186.5 OQS07552.1 - 0.00022 20.7 0.2 0.78 9.3 0.0 3.7 4 0 0 4 4 4 1 Atypical Arm repeat V-ATPase_H_N PF03224.14 OQS07552.1 - 0.0011 18.3 1.4 0.011 15.0 1.3 2.1 1 1 0 1 1 1 1 V-ATPase subunit H UNC45-central PF11701.8 OQS07552.1 - 0.0014 18.6 2.5 0.36 10.8 1.4 2.6 1 1 1 2 2 2 2 Myosin-binding striated muscle assembly central V-ATPase_H_C PF11698.8 OQS07552.1 - 0.0018 18.4 4.9 0.023 14.8 0.6 3.3 1 1 3 4 4 4 2 V-ATPase subunit H Adaptin_N PF01602.20 OQS07552.1 - 0.002 16.8 1.4 0.019 13.5 0.1 2.5 1 1 2 3 3 3 2 Adaptin N terminal region Cnd1 PF12717.7 OQS07552.1 - 0.0065 16.5 3.1 0.24 11.5 0.5 2.8 1 1 2 3 3 3 2 non-SMC mitotic condensation complex subunit 1 RTP1_C1 PF10363.9 OQS07552.1 - 0.04 14.1 2.6 5 7.3 0.2 3.3 1 1 1 3 3 3 0 Required for nuclear transport of RNA pol II C-terminus 1 HEAT_PBS PF03130.16 OQS07552.1 - 0.043 14.5 6.0 1.1 10.1 1.0 4.9 4 2 0 4 4 4 0 PBS lyase HEAT-like repeat RasGEF_N_2 PF14663.6 OQS07552.1 - 0.093 13.1 3.3 8.4 6.8 0.1 3.4 2 1 1 3 3 3 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain ASFV_p27 PF06556.11 OQS07552.1 - 0.15 12.1 0.0 9.8 6.3 0.0 2.6 1 1 1 2 2 2 0 IAP-like protein p27 C-terminus NopRA1 PF16201.5 OQS07552.1 - 0.16 11.5 0.7 6.5 6.3 0.0 2.7 1 1 2 3 3 3 0 Nucleolar pre-ribosomal-associated protein 1 Questin_oxidase PF14027.6 OQS07552.1 - 0.21 11.1 3.0 1.1 8.8 0.1 2.3 1 1 1 2 2 2 0 Questin oxidase-like DUF4478 PF14793.6 OQS07552.1 - 0.26 11.2 3.2 5.7 6.9 0.1 2.9 1 1 2 3 3 3 0 Pyrimidine/purine nucleotide 5'-monophosphate nucleosidases Aconitase_B_N PF11791.8 OQS07552.1 - 0.27 11.3 11.3 0.88 9.6 0.3 4.4 1 1 4 5 5 5 0 Aconitate B N-terminal domain DUF3361 PF11841.8 OQS07552.1 - 3.2 7.7 8.7 0.72 9.8 0.8 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF3361) PRIMA1 PF16101.5 OQS07553.1 - 6.2 6.9 8.6 1.6 8.7 1.7 2.3 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 ASH PF15780.5 OQS07554.1 - 7.4e-19 67.8 3.5 0.0048 17.1 0.0 8.5 8 0 0 8 8 8 6 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin Motile_Sperm PF00635.26 OQS07554.1 - 4.4e-07 29.7 0.4 2.7 7.9 0.0 6.0 6 0 0 6 6 6 2 MSP (Major sperm protein) domain PapD-like PF14874.6 OQS07554.1 - 1.5e-05 25.1 3.5 0.22 11.7 0.0 5.7 6 1 1 7 7 7 1 Flagellar-associated PapD-like Cadherin PF00028.17 OQS07554.1 - 0.073 13.5 0.0 33 5.0 0.0 3.7 4 0 0 4 4 4 0 Cadherin domain Parvo_coat_N PF08398.10 OQS07554.1 - 0.13 12.4 0.1 0.3 11.3 0.1 1.5 1 0 0 1 1 1 0 Parvovirus coat protein VP1 Lactamase_B PF00753.27 OQS07555.1 - 1.3e-09 38.3 0.1 2.8e-09 37.2 0.1 1.5 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily EF-hand_8 PF13833.6 OQS07555.1 - 5.5e-09 35.7 2.1 4.3e-08 32.9 0.6 2.6 2 0 0 2 2 2 1 EF-hand domain pair cNMP_binding PF00027.29 OQS07555.1 - 7.1e-09 35.6 0.0 0.00028 20.9 0.0 3.4 2 1 0 2 2 2 2 Cyclic nucleotide-binding domain Lactamase_B_2 PF12706.7 OQS07555.1 - 1.8e-06 27.6 0.0 6.7e-06 25.8 0.0 1.9 1 0 0 1 1 1 1 Beta-lactamase superfamily domain EF-hand_6 PF13405.6 OQS07555.1 - 1.8e-05 24.3 0.2 7.8e-05 22.3 0.2 2.1 1 0 0 1 1 1 1 EF-hand domain EF-hand_7 PF13499.6 OQS07555.1 - 8.2e-05 23.0 0.8 0.00025 21.4 0.4 2.0 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.32 OQS07555.1 - 0.00031 20.1 2.4 0.00093 18.6 2.4 1.9 1 0 0 1 1 1 1 EF hand EF-hand_5 PF13202.6 OQS07555.1 - 0.0054 16.2 0.2 0.012 15.1 0.2 1.6 1 0 0 1 1 1 1 EF hand His_Phos_2 PF00328.22 OQS07556.1 - 1.1e-81 275.2 0.0 8.4e-42 143.9 0.0 2.2 1 1 1 2 2 2 2 Histidine phosphatase superfamily (branch 2) PPIP5K2_N PF18086.1 OQS07556.1 - 2.9e-38 129.9 0.1 6e-38 128.9 0.1 1.6 1 0 0 1 1 1 1 Diphosphoinositol pentakisphosphate kinase 2 N-terminal domain RimK PF08443.11 OQS07556.1 - 0.00024 20.7 0.0 0.0006 19.5 0.0 1.6 1 0 0 1 1 1 1 RimK-like ATP-grasp domain Sugar_tr PF00083.24 OQS07557.1 - 3.1e-244 810.8 93.2 1.6e-85 287.7 24.7 3.1 3 0 0 3 3 3 3 Sugar (and other) transporter MFS_1 PF07690.16 OQS07557.1 - 1.4e-73 247.9 105.0 1.4e-26 93.3 24.4 5.8 1 1 4 6 6 6 4 Major Facilitator Superfamily MFS_2 PF13347.6 OQS07557.1 - 2.2e-12 46.3 69.2 0.00054 18.6 7.9 7.5 6 2 1 7 7 7 6 MFS/sugar transport protein TRI12 PF06609.13 OQS07557.1 - 5.5e-06 25.1 41.6 0.00019 20.0 1.4 5.1 5 0 0 5 5 5 3 Fungal trichothecene efflux pump (TRI12) LRR19-TM PF15176.6 OQS07557.1 - 0.37 10.8 2.9 35 4.5 0.1 3.5 3 0 0 3 3 3 0 Leucine-rich repeat family 19 TM domain Myb_DNA-binding PF00249.31 OQS07558.1 - 4.8e-37 125.9 15.9 5.5e-14 52.1 0.8 3.8 4 0 0 4 4 4 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OQS07558.1 - 1.6e-31 108.4 4.5 1.2e-14 54.3 0.1 3.5 1 1 2 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OQS07558.1 - 0.0004 20.2 0.8 0.34 10.8 0.1 3.6 4 0 0 4 4 4 1 Myb DNA-binding like MADF_DNA_bdg PF10545.9 OQS07558.1 - 0.0013 19.0 5.8 0.65 10.3 0.2 4.0 4 0 0 4 4 4 2 Alcohol dehydrogenase transcription factor Myb/SANT-like Rap1_C PF11626.8 OQS07558.1 - 0.0032 17.5 0.5 0.6 10.2 0.1 3.0 2 1 1 3 3 3 2 TRF2-interacting telomeric protein/Rap1 - C terminal domain SLIDE PF09111.10 OQS07558.1 - 0.0072 16.3 1.5 1.3 9.1 0.0 3.5 3 2 1 5 5 5 1 SLIDE Myb_DNA-bind_4 PF13837.6 OQS07558.1 - 0.092 13.1 8.4 7.9 6.9 0.1 4.5 4 0 0 4 4 4 0 Myb/SANT-like DNA-binding domain Ank_4 PF13637.6 OQS07559.1 - 1.4e-18 67.0 1.5 3.3e-14 53.0 0.1 2.3 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 OQS07559.1 - 8.6e-14 51.9 0.3 1.2e-13 51.4 0.3 1.2 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OQS07559.1 - 5.6e-13 48.8 0.8 1.2e-10 41.4 0.0 2.9 1 1 2 3 3 3 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQS07559.1 - 1e-11 43.9 0.1 2.6e-05 24.3 0.0 3.0 3 0 0 3 3 3 2 Ankyrin repeat Ank PF00023.30 OQS07559.1 - 6.9e-10 38.9 0.9 3.2e-05 24.2 0.0 3.0 3 0 0 3 3 3 2 Ankyrin repeat ATG13 PF10033.9 OQS07560.1 - 2.2e-20 73.4 0.0 9e-16 58.3 0.0 2.8 1 1 1 2 2 2 2 Autophagy-related protein 13 SpoVAB PF13782.6 OQS07561.1 - 0.019 15.3 0.7 0.036 14.4 0.1 1.7 2 0 0 2 2 2 0 Stage V sporulation protein AB DUF2567 PF10821.8 OQS07561.1 - 0.15 12.1 0.2 0.15 12.1 0.2 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2567) EamA PF00892.20 OQS07564.1 - 6.4e-25 87.9 38.1 5.1e-13 49.4 16.7 2.0 2 0 0 2 2 2 2 EamA-like transporter family PAP_PilO PF06864.12 OQS07564.1 - 0.15 10.9 0.2 0.22 10.3 0.2 1.2 1 0 0 1 1 1 0 Pilin accessory protein (PilO) DUF2554 PF10829.8 OQS07564.1 - 1.2 9.6 2.9 19 5.7 0.3 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2554) Herpes_LMP1 PF05297.11 OQS07564.1 - 6.6 5.8 6.4 11 5.2 6.4 1.4 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) Zip PF02535.22 OQS07565.1 - 2.2e-38 132.3 11.6 3.6e-37 128.3 11.6 1.9 1 1 0 1 1 1 1 ZIP Zinc transporter Tmemb_14 PF03647.13 OQS07565.1 - 0.018 15.8 2.7 0.018 15.8 2.7 2.6 1 1 1 2 2 2 0 Transmembrane proteins 14C DUF272 PF03312.15 OQS07565.1 - 0.069 13.4 0.0 0.13 12.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF272) TssN PF17555.2 OQS07565.1 - 0.35 10.2 2.4 0.72 9.2 2.4 1.6 1 0 0 1 1 1 0 Type VI secretion system, TssN EamA PF00892.20 OQS07566.1 - 4.2e-71 237.5 144.9 1.2e-12 48.2 18.6 8.8 8 2 0 8 8 8 8 EamA-like transporter family DUF4235 PF14019.6 OQS07566.1 - 2.4 8.3 5.2 27 4.9 0.0 4.3 5 0 0 5 5 5 0 Protein of unknown function (DUF4235) DUF247 PF03140.15 OQS07567.1 - 0.0066 15.7 0.0 0.0072 15.6 0.0 1.1 1 0 0 1 1 1 1 Plant protein of unknown function VHL_C PF17211.3 OQS07567.1 - 0.017 15.1 0.1 0.036 14.1 0.1 1.5 1 0 0 1 1 1 0 VHL box domain ECH_2 PF16113.5 OQS07567.1 - 0.05 13.1 0.3 0.059 12.9 0.3 1.2 1 0 0 1 1 1 0 Enoyl-CoA hydratase/isomerase DUF4393 PF14337.6 OQS07568.1 - 0.082 12.7 1.7 0.64 9.8 1.7 2.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4393) Corona_M PF01635.18 OQS07568.1 - 0.095 12.0 0.2 0.33 10.2 0.0 1.9 2 0 0 2 2 2 0 Coronavirus M matrix/glycoprotein NOA36 PF06524.12 OQS07568.1 - 2.9 7.1 10.1 4.8 6.4 10.1 1.2 1 0 0 1 1 1 0 NOA36 protein Glyco_hydro_17 PF00332.18 OQS07570.1 - 4.1e-07 29.9 6.9 0.00088 19.0 1.5 2.2 1 1 1 2 2 2 2 Glycosyl hydrolases family 17 PLATZ PF04640.14 OQS07571.1 - 0.021 15.4 6.5 0.028 15.0 6.5 1.4 1 1 0 1 1 1 0 PLATZ transcription factor AMP-binding PF00501.28 OQS07573.1 - 1.6e-97 326.8 0.0 2e-97 326.5 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 OQS07573.1 - 1.6e-05 25.8 0.0 5e-05 24.2 0.0 1.9 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Phage_sheath_1C PF17482.2 OQS07573.1 - 0.055 13.4 0.0 0.12 12.4 0.0 1.5 1 0 0 1 1 1 0 Phage tail sheath C-terminal domain DAGAT PF03982.13 OQS07574.1 - 1e-43 149.3 1.0 2.2e-43 148.3 0.0 1.9 2 0 0 2 2 2 1 Diacylglycerol acyltransferase Peptidase_C13 PF01650.18 OQS07575.1 - 1.5e-44 152.5 0.5 2e-44 152.1 0.5 1.1 1 0 0 1 1 1 1 Peptidase C13 family EF-hand_1 PF00036.32 OQS07576.1 - 1e-14 52.9 8.3 5.2e-05 22.5 0.2 4.2 4 0 0 4 4 4 3 EF hand EF-hand_5 PF13202.6 OQS07576.1 - 6.4e-14 50.7 8.6 5.3e-05 22.5 0.4 4.0 3 0 0 3 3 3 3 EF hand EF-hand_7 PF13499.6 OQS07576.1 - 1.2e-09 38.5 3.1 0.00029 21.2 0.3 3.3 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.6 OQS07576.1 - 2.1e-09 36.5 6.1 0.0074 16.1 0.1 4.4 4 0 0 4 4 4 3 EF-hand domain WD40 PF00400.32 OQS07576.1 - 1.2e-08 35.4 18.8 0.37 11.7 0.1 9.1 9 0 0 9 9 9 3 WD domain, G-beta repeat EF-hand_8 PF13833.6 OQS07576.1 - 1.9e-05 24.4 2.8 0.0037 17.1 0.2 3.5 2 1 1 3 3 3 2 EF-hand domain pair ANAPC4_WD40 PF12894.7 OQS07576.1 - 0.00028 21.1 0.1 2.6 8.4 0.0 3.7 3 0 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Ras PF00071.22 OQS07577.1 - 1.3e-18 67.1 0.0 6.4e-15 55.1 0.0 3.2 3 0 0 3 3 3 1 Ras family Roc PF08477.13 OQS07577.1 - 5.8e-14 52.3 0.0 6e-10 39.4 0.0 3.3 3 0 0 3 3 3 2 Ras of Complex, Roc, domain of DAPkinase EF_assoc_2 PF08356.12 OQS07577.1 - 4.5e-11 42.6 0.0 9.8e-11 41.5 0.0 1.6 1 0 0 1 1 1 1 EF hand associated GTP_EFTU PF00009.27 OQS07577.1 - 3.2e-06 26.8 0.7 0.00023 20.7 0.1 3.2 3 1 1 4 4 4 1 Elongation factor Tu GTP binding domain EF_assoc_1 PF08355.12 OQS07577.1 - 3.2e-06 26.7 0.1 1.2e-05 24.8 0.1 2.0 2 0 0 2 2 1 1 EF hand associated EF-hand_1 PF00036.32 OQS07577.1 - 8.1e-06 25.0 0.2 3e-05 23.2 0.2 2.0 1 0 0 1 1 1 1 EF hand RsgA_GTPase PF03193.16 OQS07577.1 - 9.8e-06 25.6 1.8 0.25 11.2 0.0 4.0 3 1 1 4 4 4 2 RsgA GTPase Arf PF00025.21 OQS07577.1 - 1.2e-05 24.8 0.1 0.12 11.8 0.1 2.7 2 1 0 2 2 2 2 ADP-ribosylation factor family MMR_HSR1 PF01926.23 OQS07577.1 - 2.6e-05 24.2 1.0 0.0031 17.6 0.1 3.2 2 1 0 2 2 2 1 50S ribosome-binding GTPase EF-hand_6 PF13405.6 OQS07577.1 - 5e-05 22.9 0.1 0.00018 21.2 0.1 2.0 1 0 0 1 1 1 1 EF-hand domain EF-hand_7 PF13499.6 OQS07577.1 - 5.2e-05 23.6 2.5 6.9e-05 23.2 0.2 2.4 4 0 0 4 4 1 1 EF-hand domain pair EF-hand_5 PF13202.6 OQS07577.1 - 7.9e-05 22.0 0.1 0.00018 20.9 0.1 1.6 1 0 0 1 1 1 1 EF hand G-alpha PF00503.20 OQS07577.1 - 9.4e-05 21.7 0.7 0.11 11.6 0.0 3.2 2 1 0 3 3 3 1 G-protein alpha subunit TniB PF05621.11 OQS07577.1 - 0.00031 20.2 0.1 0.4 10.1 0.0 2.4 2 0 0 2 2 2 2 Bacterial TniB protein EF-hand_8 PF13833.6 OQS07577.1 - 0.004 17.0 0.7 0.02 14.7 0.2 2.3 1 1 1 2 2 2 1 EF-hand domain pair Dynamin_N PF00350.23 OQS07577.1 - 0.0043 17.1 1.9 0.05 13.7 0.4 2.5 2 1 0 2 2 2 1 Dynamin family Septin PF00735.18 OQS07577.1 - 0.011 15.1 0.3 0.099 11.9 0.1 2.1 2 0 0 2 2 2 0 Septin ATPase_2 PF01637.18 OQS07577.1 - 0.012 15.6 0.0 1.3 8.9 0.0 2.4 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea AAA_22 PF13401.6 OQS07577.1 - 0.015 15.5 0.0 8.5 6.7 0.0 3.0 2 1 0 2 2 2 0 AAA domain AAA_24 PF13479.6 OQS07577.1 - 0.017 14.8 0.0 4.4 7.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 OQS07577.1 - 0.021 14.4 0.2 6.9 6.1 0.0 3.0 3 1 0 3 3 3 0 P-loop containing dynein motor region AAA_16 PF13191.6 OQS07577.1 - 0.029 14.8 0.0 14 6.1 0.0 2.8 2 0 0 2 2 2 0 AAA ATPase domain DAP3 PF10236.9 OQS07577.1 - 0.031 13.5 0.0 0.44 9.7 0.0 2.2 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 AAA_29 PF13555.6 OQS07577.1 - 0.064 13.0 0.4 8.6 6.2 0.0 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain SRPRB PF09439.10 OQS07577.1 - 0.12 11.8 0.2 2.8 7.3 0.0 2.8 3 0 0 3 3 3 0 Signal recognition particle receptor beta subunit AAA_14 PF13173.6 OQS07577.1 - 0.15 12.1 0.0 7.4 6.6 0.0 2.8 2 1 0 2 2 2 0 AAA domain PduV-EutP PF10662.9 OQS07577.1 - 0.15 11.8 0.2 36 4.1 0.0 3.5 4 0 0 4 4 4 0 Ethanolamine utilisation - propanediol utilisation Virul_Fac PF10139.9 OQS07577.1 - 0.28 9.4 1.2 1.2 7.3 0.5 1.9 2 0 0 2 2 2 0 Putative bacterial virulence factor RsgA_GTPase PF03193.16 OQS07578.1 - 0.02 14.8 0.0 0.045 13.6 0.0 1.6 1 0 0 1 1 1 0 RsgA GTPase AAA_5 PF07728.14 OQS07578.1 - 0.095 12.7 0.0 0.3 11.1 0.0 1.9 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_29 PF13555.6 OQS07578.1 - 0.17 11.6 0.3 0.38 10.5 0.0 1.7 2 0 0 2 2 2 0 P-loop containing region of AAA domain ABC_tran PF00005.27 OQS07578.1 - 0.18 12.3 0.0 0.46 11.0 0.0 1.7 1 0 0 1 1 1 0 ABC transporter HATPase_c PF02518.26 OQS07580.1 - 0.001 19.5 0.1 0.003 18.0 0.0 1.9 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Topo-VIb_trans PF09239.11 OQS07580.1 - 0.0033 17.3 0.0 0.0056 16.5 0.0 1.4 1 0 0 1 1 1 1 Topoisomerase VI B subunit, transducer HATPase_c_3 PF13589.6 OQS07580.1 - 0.19 11.6 0.2 0.58 10.0 0.2 1.9 1 1 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Pkinase PF00069.25 OQS07581.1 - 5.3e-46 157.1 0.0 7.1e-46 156.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQS07581.1 - 8.9e-32 110.4 0.0 1.3e-31 109.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 OQS07581.1 - 0.0011 18.4 0.0 0.002 17.5 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 OQS07581.1 - 0.0027 16.7 0.0 0.0041 16.1 0.0 1.4 1 0 0 1 1 1 1 Haspin like kinase domain DnaB_2 PF07261.11 OQS07581.1 - 0.0096 15.6 0.2 4.7 7.0 0.0 2.3 2 0 0 2 2 2 2 Replication initiation and membrane attachment RIO1 PF01163.22 OQS07581.1 - 0.015 14.9 0.0 0.028 14.0 0.0 1.4 1 0 0 1 1 1 0 RIO1 family APH PF01636.23 OQS07581.1 - 0.069 13.1 0.2 0.13 12.2 0.2 1.6 1 1 0 1 1 1 0 Phosphotransferase enzyme family DUF89 PF01937.19 OQS07582.1 - 2.4e-72 243.8 0.0 3e-72 243.5 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF89 IspA PF04279.15 OQS07583.1 - 0.0095 16.1 9.5 0.035 14.3 9.5 1.8 1 1 0 1 1 1 1 Intracellular septation protein A EamA PF00892.20 OQS07583.1 - 0.034 14.3 1.1 0.034 14.3 1.1 2.8 2 1 1 3 3 3 0 EamA-like transporter family Ribosomal_S17e PF00833.18 OQS07586.1 - 9.9e-58 193.4 0.3 1.2e-57 193.1 0.3 1.0 1 0 0 1 1 1 1 Ribosomal S17 Creatinase_N_2 PF16189.5 OQS07587.1 - 1e-45 155.7 1.3 3.2e-45 154.1 0.7 2.0 2 0 0 2 2 2 1 Creatinase/Prolidase N-terminal domain Peptidase_M24 PF00557.24 OQS07587.1 - 2.7e-39 135.0 0.0 4.9e-39 134.2 0.0 1.5 1 0 0 1 1 1 1 Metallopeptidase family M24 Creatinase_N PF01321.18 OQS07587.1 - 2.1e-22 80.2 0.2 1.3e-15 58.2 0.1 2.5 2 0 0 2 2 2 2 Creatinase/Prolidase N-terminal domain Peptidase_M24_C PF16188.5 OQS07587.1 - 8e-18 64.3 0.1 2.5e-17 62.7 0.1 1.9 1 0 0 1 1 1 1 C-terminal region of peptidase_M24 Erf4 PF10256.9 OQS07587.1 - 2e-05 24.6 0.0 6.7e-05 23.0 0.0 1.8 2 0 0 2 2 2 1 Golgin subfamily A member 7/ERF4 family HTH_Tnp_4 PF13613.6 OQS07587.1 - 0.11 12.2 0.0 0.61 9.9 0.0 2.2 2 0 0 2 2 2 0 Helix-turn-helix of DDE superfamily endonuclease Tim17 PF02466.19 OQS07588.1 - 5.8e-16 58.8 6.3 7.8e-16 58.4 6.3 1.2 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Peptidase_S9 PF00326.21 OQS07589.1 - 7.2e-24 84.4 0.0 2.7e-23 82.6 0.0 1.9 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 OQS07589.1 - 1.1e-08 35.0 0.3 8.6e-07 28.8 0.9 2.3 1 1 1 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 OQS07589.1 - 2.2e-07 30.4 0.6 2.8e-05 23.5 0.7 2.2 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 OQS07589.1 - 0.00053 20.7 1.9 0.001 19.7 1.9 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family PD40 PF07676.12 OQS07589.1 - 0.0076 16.2 0.5 2.4 8.2 0.0 3.4 3 0 0 3 3 3 1 WD40-like Beta Propeller Repeat DLH PF01738.18 OQS07589.1 - 0.019 14.5 0.0 0.035 13.7 0.0 1.3 1 0 0 1 1 1 0 Dienelactone hydrolase family Glyco_hydro_80 PF13647.6 OQS07589.1 - 0.05 13.1 0.0 0.088 12.3 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase family 80 of chitosanase A COesterase PF00135.28 OQS07589.1 - 0.094 11.6 0.0 0.15 10.9 0.0 1.2 1 0 0 1 1 1 0 Carboxylesterase family Acetyltransf_13 PF13880.6 OQS07590.1 - 7.1e-24 83.6 0.0 1.2e-23 82.9 0.0 1.4 1 0 0 1 1 1 1 ESCO1/2 acetyl-transferase zf-C2H2_3 PF13878.6 OQS07590.1 - 3.5e-13 49.1 1.1 4.8e-13 48.7 0.1 1.8 2 0 0 2 2 2 1 zinc-finger of acetyl-transferase ESCO Acetyltransf_7 PF13508.7 OQS07590.1 - 9.7e-05 22.7 0.0 0.00031 21.1 0.0 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 OQS07590.1 - 0.00041 20.6 0.0 0.00073 19.8 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 OQS07590.1 - 0.0064 16.4 0.1 0.019 14.9 0.0 1.9 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain ATP11 PF06644.11 OQS07591.1 - 2.1e-32 113.0 0.1 2.6e-32 112.7 0.1 1.0 1 0 0 1 1 1 1 ATP11 protein DisA-linker PF10635.9 OQS07591.1 - 0.018 14.8 0.1 2.6 7.8 0.0 2.3 2 0 0 2 2 2 0 DisA bacterial checkpoint controller linker region EF-hand_7 PF13499.6 OQS07592.1 - 6.2e-26 90.6 11.1 2.8e-14 53.3 3.7 2.8 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 OQS07592.1 - 2.2e-24 83.1 11.0 9.1e-08 31.1 0.3 4.6 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.6 OQS07592.1 - 4.4e-20 69.8 5.2 1.5e-05 24.5 0.1 4.8 4 0 0 4 4 4 3 EF-hand domain EF-hand_8 PF13833.6 OQS07592.1 - 3.3e-18 65.3 10.3 5.3e-11 42.2 2.2 3.7 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.6 OQS07592.1 - 1.2e-13 49.8 4.8 0.00031 20.1 0.0 3.8 3 0 0 3 3 3 3 EF hand EF-hand_9 PF14658.6 OQS07592.1 - 2.7e-12 46.8 0.7 0.0001 22.5 0.1 2.6 2 0 0 2 2 2 2 EF-hand domain EF-hand_11 PF08976.11 OQS07592.1 - 1.3e-05 26.0 0.9 0.11 13.3 0.1 2.4 1 1 1 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 OQS07592.1 - 0.00052 19.9 4.3 0.41 10.6 0.5 2.8 2 1 1 3 3 3 2 Cytoskeletal-regulatory complex EF hand Staphylokinase PF02821.16 OQS07592.1 - 0.0026 18.2 0.5 0.032 14.7 0.1 2.5 1 1 1 2 2 2 1 Staphylokinase/Streptokinase family Dockerin_1 PF00404.18 OQS07592.1 - 0.013 15.6 0.4 8.2 6.7 0.0 2.7 2 1 1 3 3 3 0 Dockerin type I domain SurA_N_3 PF13624.6 OQS07592.1 - 0.076 12.8 2.1 2.6 7.8 0.4 2.3 1 1 1 2 2 2 0 SurA N-terminal domain Caleosin PF05042.13 OQS07592.1 - 0.083 12.8 0.2 9.9 6.1 0.0 3.0 2 1 1 3 3 3 0 Caleosin related protein Ribosomal_L11 PF00298.19 OQS07592.1 - 0.13 12.8 0.0 0.4 11.2 0.0 1.8 1 1 0 1 1 1 0 Ribosomal protein L11, RNA binding domain SKN1 PF03935.15 OQS07593.1 - 3.3e-55 187.4 15.8 6.8e-38 130.3 9.2 4.5 3 1 0 3 3 3 3 Beta-glucan synthesis-associated protein (SKN1) VPS13_C PF16909.5 OQS07593.1 - 1.1e-27 96.9 2.1 5.3e-24 85.0 0.2 2.6 2 0 0 2 2 2 2 Vacuolar-sorting-associated 13 protein C-terminal SHR-BD PF06650.12 OQS07593.1 - 6.5e-24 84.7 0.5 2.1e-23 83.0 0.1 2.2 2 0 0 2 2 2 1 SHR-binding domain of vacuolar-sorting associated protein 13 C2 PF00168.30 OQS07593.1 - 5.3e-18 65.2 0.2 7.3e-09 35.8 0.1 2.7 2 0 0 2 2 2 2 C2 domain EF-hand_1 PF00036.32 OQS07593.1 - 4.8e-10 38.3 0.3 2.3e-05 23.6 0.1 2.9 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 OQS07593.1 - 2.9e-09 37.3 1.6 8.8e-09 35.7 1.6 1.9 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 OQS07593.1 - 6.5e-09 35.0 1.0 0.00056 19.6 0.1 2.9 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 OQS07593.1 - 5.5e-07 28.8 0.7 0.00018 20.9 0.1 2.9 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 OQS07593.1 - 0.0059 16.4 1.3 0.014 15.2 0.5 2.2 3 0 0 3 3 3 1 EF-hand domain pair EB PF01683.18 OQS07593.1 - 0.0086 16.3 0.9 0.0086 16.3 0.9 2.0 2 0 0 2 2 2 1 EB module DUF347 PF03988.12 OQS07593.1 - 0.043 14.0 0.1 0.1 12.8 0.1 1.6 1 0 0 1 1 1 0 Repeat of Unknown Function (DUF347) SNAP PF14938.6 OQS07594.1 - 9.9e-44 149.9 17.9 1.2e-43 149.6 17.9 1.0 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_12 PF13424.6 OQS07594.1 - 6.3e-05 23.2 12.3 0.0039 17.4 2.7 2.7 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 OQS07594.1 - 0.00016 21.5 18.1 0.54 10.5 2.3 4.5 1 1 1 4 4 4 3 Tetratricopeptide repeat Pterin_4a PF01329.19 OQS07594.1 - 0.01 15.9 2.7 0.38 11.0 0.1 2.2 1 1 1 2 2 2 0 Pterin 4 alpha carbinolamine dehydratase TPR_1 PF00515.28 OQS07594.1 - 0.015 15.1 15.3 2 8.3 0.3 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat MIT PF04212.18 OQS07594.1 - 0.023 14.7 14.1 0.21 11.7 2.4 3.2 3 0 0 3 3 3 0 MIT (microtubule interacting and transport) domain DHR-2 PF06920.13 OQS07594.1 - 0.025 13.2 2.2 0.17 10.5 0.7 2.0 1 1 1 2 2 2 0 Dock homology region 2 DUF357 PF04010.13 OQS07594.1 - 0.03 14.4 4.5 0.34 11.0 0.5 2.8 1 1 2 3 3 3 0 Protein of unknown function (DUF357) Spatacsin_C PF14649.6 OQS07594.1 - 0.032 13.3 10.5 0.22 10.6 10.5 1.9 1 1 0 1 1 1 0 Spatacsin C-terminus TPR_16 PF13432.6 OQS07594.1 - 0.064 13.9 13.0 1.3 9.7 3.2 3.3 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 OQS07594.1 - 0.067 13.4 13.1 6.6 7.2 0.4 4.9 3 2 1 5 5 5 0 Tetratricopeptide repeat RPN7 PF10602.9 OQS07594.1 - 0.083 12.6 3.2 0.18 11.5 0.3 2.3 1 1 0 2 2 2 0 26S proteasome subunit RPN7 NSF PF02071.20 OQS07594.1 - 0.18 12.7 22.4 6.7 8.0 1.3 6.1 6 1 1 7 7 6 0 Aromatic-di-Alanine (AdAR) repeat TPR_14 PF13428.6 OQS07594.1 - 0.34 11.8 8.6 3.6 8.7 0.3 3.4 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.6 OQS07594.1 - 0.49 10.3 0.1 0.49 10.3 0.1 4.2 3 2 3 6 6 6 0 Tetratricopeptide repeat TPR_7 PF13176.6 OQS07594.1 - 0.52 10.5 17.1 3.4 7.9 0.5 5.0 3 2 2 5 5 5 0 Tetratricopeptide repeat TPR_6 PF13174.6 OQS07594.1 - 0.69 10.7 12.4 17 6.3 0.4 4.4 2 1 3 5 5 5 0 Tetratricopeptide repeat BT1 PF03092.16 OQS07595.1 - 1.2e-80 271.3 15.1 2.5e-47 161.3 4.7 2.2 1 1 1 2 2 2 2 BT1 family Peptidase_C1 PF00112.23 OQS07595.1 - 3e-76 256.3 4.4 6.2e-76 255.3 4.4 1.6 1 0 0 1 1 1 1 Papain family cysteine protease Ribosomal_S13 PF00416.22 OQS07595.1 - 2.3e-44 150.9 0.8 4.3e-44 150.0 0.8 1.4 1 0 0 1 1 1 1 Ribosomal protein S13/S18 Y_phosphatase2 PF03162.13 OQS07595.1 - 6.5e-32 110.4 0.0 1.4e-31 109.3 0.0 1.5 1 0 0 1 1 1 1 Tyrosine phosphatase family Ricin_B_lectin PF00652.22 OQS07595.1 - 4.8e-27 94.7 15.2 3.6e-13 49.9 7.5 2.8 2 0 0 2 2 2 2 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.6 OQS07595.1 - 2.4e-13 50.6 17.6 3.7e-05 24.4 1.0 3.7 2 1 1 3 3 3 3 Ricin-type beta-trefoil lectin domain-like E1_DerP2_DerF2 PF02221.15 OQS07595.1 - 2.4e-13 50.7 0.0 4.8e-13 49.7 0.0 1.5 1 0 0 1 1 1 1 ML domain Inhibitor_I29 PF08246.12 OQS07595.1 - 8e-09 35.8 1.9 2.6e-08 34.2 1.9 2.0 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) CDtoxinA PF03498.14 OQS07595.1 - 1.1e-06 28.3 4.9 0.0038 16.8 1.4 2.8 3 0 0 3 3 3 2 Cytolethal distending toxin A/C domain Acetyltransf_1 PF00583.25 OQS07595.1 - 4.9e-05 23.5 0.0 0.00015 22.0 0.0 1.8 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Peptidase_C1_2 PF03051.15 OQS07595.1 - 0.00019 20.3 1.6 0.011 14.6 0.7 2.5 2 0 0 2 2 2 1 Peptidase C1-like family PUCC PF03209.15 OQS07595.1 - 0.0003 19.9 3.0 0.0003 19.9 3.0 2.6 2 1 1 3 3 3 1 PUCC protein FR47 PF08445.10 OQS07595.1 - 0.0037 17.2 0.0 0.018 15.0 0.0 2.1 2 0 0 2 2 1 1 FR47-like protein Glyco_hydro_17 PF00332.18 OQS07595.1 - 0.0061 16.2 1.5 0.011 15.3 1.5 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 17 Acetyltransf_3 PF13302.7 OQS07595.1 - 0.019 15.6 0.0 0.05 14.3 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 OQS07595.1 - 0.021 15.3 0.0 0.062 13.7 0.0 1.9 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF2746 PF10874.8 OQS07595.1 - 0.029 14.8 0.0 0.091 13.2 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2746) Acetyltransf_10 PF13673.7 OQS07595.1 - 0.046 13.6 0.0 0.23 11.4 0.0 2.1 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain FbpA PF05833.11 OQS07595.1 - 0.17 10.6 0.0 0.28 9.9 0.0 1.2 1 0 0 1 1 1 0 Fibronectin-binding protein A N-terminus (FbpA) Sds3 PF08598.11 OQS07596.1 - 0.0031 17.6 6.7 0.037 14.0 7.5 2.0 2 1 0 2 2 2 1 Sds3-like DUF3747 PF12565.8 OQS07596.1 - 0.048 13.0 0.1 0.086 12.2 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3747) DUF2508 PF10704.9 OQS07596.1 - 0.21 11.8 2.7 0.38 11.0 0.5 2.4 1 1 0 2 2 2 0 Protein of unknown function (DUF2508) HTH_57 PF18679.1 OQS07596.1 - 0.53 10.6 3.5 0.32 11.3 0.6 2.0 2 0 0 2 2 2 0 ThcOx helix turn helix domain PALP PF00291.25 OQS07597.1 - 2.6e-68 230.6 0.8 3e-68 230.4 0.8 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme DAGK_cat PF00781.24 OQS07597.1 - 0.096 12.3 0.3 0.82 9.3 0.1 2.4 2 1 0 2 2 2 0 Diacylglycerol kinase catalytic domain LSM PF01423.22 OQS07598.1 - 2.8e-22 78.2 0.2 3.2e-22 78.0 0.2 1.0 1 0 0 1 1 1 1 LSM domain LSM14 PF12701.7 OQS07598.1 - 0.081 13.0 0.0 0.1 12.7 0.0 1.3 1 1 0 1 1 1 0 Scd6-like Sm domain AAA_18 PF13238.6 OQS07599.1 - 4.2e-29 101.7 0.2 7.5e-29 100.9 0.0 1.4 2 0 0 2 2 1 1 AAA domain AAA_17 PF13207.6 OQS07599.1 - 4.3e-08 33.7 0.1 1.1e-07 32.3 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.6 OQS07599.1 - 2e-05 24.9 0.5 6e-05 23.3 0.2 2.0 2 1 0 2 2 2 1 AAA domain AAA_33 PF13671.6 OQS07599.1 - 7.7e-05 22.9 0.1 0.0016 18.6 0.0 2.2 1 1 1 2 2 2 1 AAA domain AAA PF00004.29 OQS07599.1 - 9.7e-05 22.8 0.7 0.00024 21.5 0.1 1.9 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) ADK PF00406.22 OQS07599.1 - 0.00014 22.0 0.1 0.004 17.3 0.0 2.1 2 0 0 2 2 2 1 Adenylate kinase NTPase_1 PF03266.15 OQS07599.1 - 0.00042 20.3 0.1 0.0011 18.9 0.0 1.8 2 0 0 2 2 2 1 NTPase KTI12 PF08433.10 OQS07599.1 - 0.00048 19.7 0.1 0.00087 18.8 0.0 1.4 2 0 0 2 2 2 1 Chromatin associated protein KTI12 AAA_22 PF13401.6 OQS07599.1 - 0.0011 19.2 1.1 0.0055 17.0 1.1 2.3 1 1 0 1 1 1 1 AAA domain Sigma54_activ_2 PF14532.6 OQS07599.1 - 0.0015 18.7 0.0 0.0031 17.6 0.0 1.6 1 1 0 1 1 1 1 Sigma-54 interaction domain ATPase PF06745.13 OQS07599.1 - 0.002 17.5 0.3 0.0092 15.3 0.0 1.9 2 0 0 2 2 2 1 KaiC AAA_5 PF07728.14 OQS07599.1 - 0.0026 17.7 0.0 0.0042 17.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Cytidylate_kin PF02224.18 OQS07599.1 - 0.0029 17.4 0.0 0.0033 17.2 0.0 1.4 1 1 0 1 1 1 1 Cytidylate kinase RuvB_N PF05496.12 OQS07599.1 - 0.0035 17.1 0.0 0.0053 16.5 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 OQS07599.1 - 0.0041 17.5 0.0 0.0064 16.9 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain SKI PF01202.22 OQS07599.1 - 0.0054 16.9 0.2 0.0096 16.1 0.2 1.7 1 1 0 1 1 1 1 Shikimate kinase dNK PF01712.19 OQS07599.1 - 0.0055 16.6 0.4 0.32 10.8 0.1 2.1 1 1 1 2 2 2 1 Deoxynucleoside kinase FtsK_SpoIIIE PF01580.18 OQS07599.1 - 0.011 15.2 0.0 0.027 13.9 0.0 1.7 1 0 0 1 1 1 0 FtsK/SpoIIIE family ResIII PF04851.15 OQS07599.1 - 0.013 15.5 0.0 0.014 15.4 0.0 1.4 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_13 PF13166.6 OQS07599.1 - 0.013 14.2 0.0 0.019 13.7 0.0 1.2 1 0 0 1 1 1 0 AAA domain TniB PF05621.11 OQS07599.1 - 0.016 14.6 0.0 0.036 13.5 0.0 1.5 1 0 0 1 1 1 0 Bacterial TniB protein AAA_19 PF13245.6 OQS07599.1 - 0.019 15.3 1.8 0.049 14.0 1.8 1.9 1 1 0 1 1 1 0 AAA domain AAA_7 PF12775.7 OQS07599.1 - 0.02 14.4 0.1 0.06 12.9 0.1 1.8 2 0 0 2 2 2 0 P-loop containing dynein motor region Cytidylate_kin2 PF13189.6 OQS07599.1 - 0.024 14.8 0.0 0.037 14.2 0.0 1.5 1 1 0 1 1 1 0 Cytidylate kinase-like family RNA_helicase PF00910.22 OQS07599.1 - 0.025 14.9 0.5 0.065 13.6 0.1 1.9 2 1 0 2 2 2 0 RNA helicase Thymidylate_kin PF02223.17 OQS07599.1 - 0.027 14.2 0.3 0.97 9.1 0.1 2.2 2 0 0 2 2 2 0 Thymidylate kinase TsaE PF02367.17 OQS07599.1 - 0.029 14.4 0.1 0.06 13.3 0.0 1.7 2 0 0 2 2 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_3 PF07726.11 OQS07599.1 - 0.034 14.0 0.0 0.075 12.9 0.0 1.6 2 0 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.17 OQS07599.1 - 0.038 13.7 0.0 0.084 12.6 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein T2SSE PF00437.20 OQS07599.1 - 0.039 13.0 0.0 0.066 12.3 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein PduV-EutP PF10662.9 OQS07599.1 - 0.045 13.5 0.2 0.14 11.9 0.1 1.8 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_24 PF13479.6 OQS07599.1 - 0.048 13.4 1.8 0.08 12.7 0.4 2.1 2 2 0 2 2 2 0 AAA domain Sigma54_activat PF00158.26 OQS07599.1 - 0.06 13.0 0.0 0.088 12.5 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain GTP_EFTU PF00009.27 OQS07599.1 - 0.062 12.8 0.1 0.23 11.0 0.0 1.9 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain AAA_30 PF13604.6 OQS07599.1 - 0.067 12.9 1.3 0.13 12.0 0.6 1.7 1 1 1 2 2 2 0 AAA domain Zeta_toxin PF06414.12 OQS07599.1 - 0.073 12.3 0.0 0.15 11.3 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin Mg_chelatase PF01078.21 OQS07599.1 - 0.075 12.4 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI SRPRB PF09439.10 OQS07599.1 - 0.086 12.3 0.0 0.96 8.9 0.0 2.1 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit AAA_14 PF13173.6 OQS07599.1 - 0.09 12.8 0.0 0.23 11.5 0.0 1.7 2 0 0 2 2 2 0 AAA domain Rad17 PF03215.15 OQS07599.1 - 0.093 12.6 0.0 0.15 11.9 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain MCM PF00493.23 OQS07599.1 - 0.11 11.5 0.0 0.53 9.3 0.0 2.0 2 0 0 2 2 2 0 MCM P-loop domain AAA_29 PF13555.6 OQS07599.1 - 0.13 12.0 0.0 0.25 11.1 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.27 OQS07599.1 - 0.14 12.6 0.1 0.24 11.9 0.1 1.7 1 1 0 1 1 1 0 ABC transporter Ribosomal_L37 PF08561.10 OQS07600.1 - 5.1e-09 36.7 2.5 6.4e-07 29.9 0.1 2.2 1 1 1 2 2 2 2 Mitochondrial ribosomal protein L37 EF_assoc_1 PF08355.12 OQS07600.1 - 0.17 11.5 0.1 0.3 10.7 0.1 1.3 1 0 0 1 1 1 0 EF hand associated 2-oxoacid_dh PF00198.23 OQS07602.1 - 1.9e-69 233.7 0.0 2.5e-69 233.3 0.0 1.1 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 OQS07602.1 - 3e-15 55.8 0.0 7.4e-15 54.5 0.0 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 OQS07602.1 - 0.00028 20.6 0.0 0.013 15.3 0.0 2.6 1 1 1 2 2 2 1 Biotin-lipoyl like Orthopox_A5L PF06193.11 OQS07602.1 - 0.022 14.2 1.5 0.056 12.9 1.5 1.7 1 0 0 1 1 1 0 Orthopoxvirus A5L protein-like HlyD_3 PF13437.6 OQS07602.1 - 0.096 13.4 0.1 4.2 8.1 0.0 2.6 1 1 1 2 2 2 0 HlyD family secretion protein YhdX PF17444.2 OQS07602.1 - 0.12 12.2 0.1 0.46 10.4 0.0 2.0 2 0 0 2 2 2 0 Uncharacterized YhdX-like VPS13 PF16908.5 OQS07603.1 - 2.2e-27 96.4 1.0 4.8e-27 95.3 1.0 1.6 1 0 0 1 1 1 1 Vacuolar sorting-associated protein 13, N-terminal Chorein_N PF12624.7 OQS07603.1 - 2.8e-17 62.9 0.8 1.1e-16 61.0 0.8 2.1 1 0 0 1 1 1 1 N-terminal region of Chorein or VPS13 PH_11 PF15413.6 OQS07603.1 - 0.0028 18.0 0.6 3.2 8.2 0.2 3.5 2 1 0 2 2 2 2 Pleckstrin homology domain SHR-BD PF06650.12 OQS07603.1 - 0.02 14.3 0.0 0.81 9.0 0.0 2.7 2 1 0 2 2 2 0 SHR-binding domain of vacuolar-sorting associated protein 13 DUF3846 PF12957.7 OQS07603.1 - 0.065 13.6 0.2 0.53 10.6 0.1 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF3846) CLAMP PF14769.6 OQS07604.1 - 2.2e-23 82.6 0.4 4.2e-23 81.7 0.4 1.5 1 0 0 1 1 1 1 Flagellar C1a complex subunit C1a-32 Pyr_redox_2 PF07992.14 OQS07605.1 - 5.8e-43 147.2 0.2 6.7e-42 143.7 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 OQS07605.1 - 2.2e-29 101.9 0.5 1.8e-28 99.0 0.1 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 OQS07605.1 - 2.9e-15 56.6 0.5 9.3e-14 51.8 0.1 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 OQS07605.1 - 4.1e-06 26.3 0.0 0.018 14.3 0.0 3.1 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OQS07605.1 - 5.5e-05 23.3 0.1 0.24 11.7 0.0 2.6 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain 3HCDH_N PF02737.18 OQS07605.1 - 0.0085 16.0 0.0 0.019 14.8 0.0 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain HI0933_like PF03486.14 OQS07605.1 - 0.01 14.5 3.3 2.4 6.8 0.2 3.0 2 1 1 3 3 3 0 HI0933-like protein DAO PF01266.24 OQS07605.1 - 0.075 12.6 0.7 6.3 6.3 0.4 2.5 2 1 1 3 3 3 0 FAD dependent oxidoreductase SWC7 PF17330.2 OQS07606.1 - 0.05 13.7 0.4 0.071 13.2 0.4 1.2 1 0 0 1 1 1 0 SWR1 chromatin-remodelling complex, sub-unit Swc7 Glucokinase PF02685.16 OQS07608.1 - 4.6e-84 282.1 0.0 6e-84 281.7 0.0 1.1 1 0 0 1 1 1 1 Glucokinase TK PF00265.18 OQS07609.1 - 7e-61 205.2 0.0 8.2e-61 204.9 0.0 1.0 1 0 0 1 1 1 1 Thymidine kinase Cyclin_N PF00134.23 OQS07611.1 - 2.7e-15 56.2 1.1 9.9e-13 48.0 0.2 2.4 2 0 0 2 2 2 2 Cyclin, N-terminal domain Cyclin_C PF02984.19 OQS07611.1 - 1.1e-06 28.7 3.0 1.1e-05 25.5 0.4 2.2 2 0 0 2 2 2 1 Cyclin, C-terminal domain Cyclin_C_2 PF16899.5 OQS07611.1 - 0.049 14.0 0.3 0.1 13.0 0.0 1.7 2 0 0 2 2 2 0 Cyclin C-terminal domain Ribonuc_red_lgC PF02867.15 OQS07612.1 - 2.1e-184 613.9 0.1 2.6e-184 613.6 0.1 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.21 OQS07612.1 - 5.5e-22 77.6 0.1 4.5e-21 74.6 0.0 2.3 2 0 0 2 2 2 1 Ribonucleotide reductase, all-alpha domain ATP-cone PF03477.16 OQS07612.1 - 1.6e-18 67.0 0.0 6.2e-18 65.1 0.0 2.1 1 0 0 1 1 1 1 ATP cone domain NIF PF03031.18 OQS07613.1 - 5.4e-66 221.2 0.1 9.8e-34 116.4 0.0 2.4 2 0 0 2 2 2 2 NLI interacting factor-like phosphatase IFT81_CH PF18383.1 OQS07614.1 - 7.3e-36 123.1 1.4 7.3e-36 123.1 1.4 3.2 3 0 0 3 3 3 1 Intraflagellar transport 81 calponin homology domain BLOC1_2 PF10046.9 OQS07614.1 - 0.026 14.8 2.6 0.026 14.8 2.6 8.0 7 1 1 8 8 8 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF2746 PF10874.8 OQS07614.1 - 0.36 11.3 3.0 10 6.6 0.0 4.3 3 1 0 3 3 3 0 Protein of unknown function (DUF2746) PEP-utilisers_N PF05524.13 OQS07614.1 - 0.43 10.8 16.7 0.2 11.9 5.2 3.3 2 0 0 2 2 2 0 PEP-utilising enzyme, N-terminal Pyr_redox_2 PF07992.14 OQS07615.1 - 2.7e-57 194.2 2.0 3.1e-57 194.0 0.1 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 OQS07615.1 - 1.3e-24 86.6 0.0 2.7e-24 85.5 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 OQS07615.1 - 9.1e-16 58.2 3.9 4.1e-12 46.5 0.0 2.7 3 0 0 3 3 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 OQS07615.1 - 6.3e-07 28.9 0.2 0.0023 17.3 0.0 2.5 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 OQS07615.1 - 3.7e-06 26.3 3.4 3.4e-05 23.1 2.7 2.2 2 0 0 2 2 2 1 FAD binding domain GIDA PF01134.22 OQS07615.1 - 4.8e-06 25.9 1.0 9.1e-06 25.0 1.0 1.4 1 0 0 1 1 1 1 Glucose inhibited division protein A FAD_oxidored PF12831.7 OQS07615.1 - 4.9e-06 26.2 0.6 8.5e-06 25.4 0.6 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase K_oxygenase PF13434.6 OQS07615.1 - 5.9e-06 25.7 0.0 0.0018 17.5 0.0 2.4 1 1 1 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) AlaDh_PNT_C PF01262.21 OQS07615.1 - 1.3e-05 24.6 0.1 7e-05 22.2 0.1 2.1 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.14 OQS07615.1 - 1.4e-05 24.0 0.2 0.00058 18.7 0.4 2.4 3 0 0 3 3 3 1 HI0933-like protein NAD_binding_8 PF13450.6 OQS07615.1 - 0.0076 16.5 2.9 0.0084 16.3 1.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 OQS07615.1 - 0.02 14.2 0.6 0.036 13.3 0.6 1.3 1 0 0 1 1 1 0 Thi4 family 3HCDH_RFF PF18321.1 OQS07615.1 - 0.052 14.0 0.2 7.7 7.0 0.0 3.2 3 0 0 3 3 3 0 3-hydroxybutyryl-CoA dehydrogenase reduced Rossmann-fold domain DAO PF01266.24 OQS07615.1 - 0.098 12.2 2.5 0.1 12.1 0.4 2.1 3 0 0 3 3 3 0 FAD dependent oxidoreductase Lar_N PF09861.9 OQS07616.1 - 9.8e-12 44.5 0.0 2.5e-11 43.1 0.0 1.7 1 1 0 1 1 1 1 Lactate racemase N-terminal domain Rieske PF00355.26 OQS07616.1 - 4.3e-08 33.0 0.1 9.9e-08 31.8 0.1 1.5 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain ABC_transp_aux PF09822.9 OQS07616.1 - 0.046 13.2 0.6 0.18 11.3 0.0 2.0 2 0 0 2 2 2 0 ABC-type uncharacterized transport system Zip PF02535.22 OQS07617.1 - 3.4e-29 102.1 14.4 1.1e-28 100.5 14.4 1.7 1 1 0 1 1 1 1 ZIP Zinc transporter PA PF02225.22 OQS07617.1 - 3.4e-19 68.6 0.0 5.4e-09 36.0 0.0 2.5 2 0 0 2 2 2 2 PA domain XPA_C PF05181.12 OQS07617.1 - 0.0049 16.8 0.4 0.023 14.6 0.4 2.1 1 1 0 1 1 1 1 XPA protein C-terminus F-box PF00646.33 OQS07617.1 - 0.032 14.1 0.0 0.1 12.5 0.0 1.9 1 0 0 1 1 1 0 F-box domain F-box-like PF12937.7 OQS07617.1 - 0.11 12.4 0.0 0.41 10.6 0.0 2.1 1 0 0 1 1 1 0 F-box-like JAB PF01398.21 OQS07618.1 - 3.2e-11 43.3 0.0 1e-10 41.6 0.0 1.9 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.6 OQS07618.1 - 5.2e-08 32.7 0.2 1.4e-07 31.3 0.1 1.8 2 0 0 2 2 2 1 Prokaryotic homologs of the JAB domain LSM PF01423.22 OQS07619.1 - 1.5e-05 24.6 0.8 1.5e-05 24.6 0.8 1.9 2 0 0 2 2 2 1 LSM domain SM-ATX PF14438.6 OQS07619.1 - 0.019 15.1 0.1 0.028 14.5 0.1 1.3 1 0 0 1 1 1 0 Ataxin 2 SM domain Vps35 PF03635.17 OQS07620.1 - 3e-211 703.8 19.6 4.1e-211 703.3 19.6 1.2 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 35 Pkinase PF00069.25 OQS07620.1 - 2.5e-60 204.1 0.1 4.3e-59 200.0 0.0 2.8 3 0 0 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQS07620.1 - 1.4e-43 149.1 0.0 3e-43 148.0 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase TauE PF01925.19 OQS07621.1 - 7.3e-36 124.0 15.3 4.2e-20 72.4 5.6 2.3 2 0 0 2 2 2 2 Sulfite exporter TauE/SafE Cystatin PF00031.21 OQS07622.1 - 0.033 14.4 0.2 0.045 14.0 0.2 1.3 1 0 0 1 1 1 0 Cystatin domain SQAPI PF16845.5 OQS07622.1 - 0.054 13.8 0.6 0.4 11.1 0.6 2.0 1 1 0 1 1 1 0 Aspartic acid proteinase inhibitor Rep_fac-A_3 PF08661.11 OQS07623.1 - 1.8e-20 73.2 0.0 1.9e-20 73.1 0.0 1.0 1 0 0 1 1 1 1 Replication factor A protein 3 F-box PF00646.33 OQS07624.1 - 0.002 17.9 0.0 0.0073 16.2 0.0 2.0 1 0 0 1 1 1 1 F-box domain LRR_4 PF12799.7 OQS07624.1 - 0.0037 17.6 12.2 0.66 10.5 0.1 5.4 4 3 2 6 6 6 3 Leucine Rich repeats (2 copies) DUF563 PF04577.14 OQS07626.1 - 6.1e-30 104.9 0.0 2.4e-29 103.0 0.0 1.9 1 1 0 2 2 2 1 Protein of unknown function (DUF563) DEAD PF00270.29 OQS07627.1 - 4.1e-44 150.4 0.1 7e-44 149.7 0.1 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OQS07627.1 - 6.5e-32 110.2 0.0 2.6e-30 105.0 0.0 2.9 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 OQS07627.1 - 9.5e-06 25.7 0.0 4.3e-05 23.6 0.0 2.0 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 OQS07627.1 - 0.0014 19.0 0.1 0.0036 17.6 0.0 1.8 2 1 0 2 2 2 1 AAA domain AAA_30 PF13604.6 OQS07627.1 - 0.0077 16.0 0.0 0.013 15.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 OQS07627.1 - 0.018 15.3 0.3 0.075 13.3 0.3 2.0 1 1 0 1 1 1 0 AAA domain TniB PF05621.11 OQS07627.1 - 0.052 12.9 0.0 0.14 11.5 0.0 1.7 2 0 0 2 2 2 0 Bacterial TniB protein DUF2075 PF09848.9 OQS07627.1 - 0.074 12.3 0.0 0.13 11.5 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Flavi_DEAD PF07652.14 OQS07627.1 - 0.086 12.8 0.2 0.63 10.0 0.0 2.5 1 1 1 2 2 2 0 Flavivirus DEAD domain Cys_Met_Meta_PP PF01053.20 OQS07628.1 - 9.9e-138 458.8 0.0 1.1e-137 458.6 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 OQS07628.1 - 1.3e-12 47.6 0.0 1.8e-12 47.1 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 OQS07628.1 - 1.8e-09 37.4 0.1 2.9e-09 36.7 0.1 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.19 OQS07628.1 - 7.7e-05 21.8 0.2 0.00013 21.1 0.2 1.3 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 OQS07628.1 - 0.0001 21.7 0.0 0.00015 21.2 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase Met_gamma_lyase PF06838.11 OQS07628.1 - 0.00021 19.9 0.1 0.00031 19.4 0.1 1.2 1 0 0 1 1 1 1 Methionine gamma-lyase GDC-P PF02347.16 OQS07628.1 - 0.0005 19.0 0.0 0.00068 18.6 0.0 1.1 1 0 0 1 1 1 1 Glycine cleavage system P-protein BRK PF07533.16 OQS07628.1 - 0.099 12.3 0.3 1.1 8.9 0.2 2.4 2 0 0 2 2 2 0 BRK domain RecQ_Zn_bind PF16124.5 OQS07629.1 - 3.6e-18 66.1 7.4 1.6e-17 64.0 7.4 2.2 1 0 0 1 1 1 1 RecQ zinc-binding DEAD PF00270.29 OQS07629.1 - 6.3e-18 65.1 0.0 1.6e-17 63.8 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OQS07629.1 - 1e-15 58.0 0.2 1e-14 54.8 0.0 2.7 3 0 0 3 3 3 1 Helicase conserved C-terminal domain RQC PF09382.10 OQS07629.1 - 1e-12 47.8 0.1 2.7e-12 46.5 0.1 1.8 1 0 0 1 1 1 1 RQC domain HRDC PF00570.23 OQS07629.1 - 3.6e-09 36.5 0.0 1.3e-08 34.6 0.0 2.1 1 0 0 1 1 1 1 HRDC domain zf-GRF PF06839.12 OQS07629.1 - 0.0005 20.1 0.2 0.0013 18.8 0.2 1.8 1 0 0 1 1 1 1 GRF zinc finger MscS_porin PF12795.7 OQS07629.1 - 0.0055 16.3 4.8 0.012 15.1 4.8 1.6 1 0 0 1 1 1 1 Mechanosensitive ion channel porin domain Med9 PF07544.13 OQS07629.1 - 0.026 14.6 7.0 2.4 8.3 2.1 3.1 1 1 1 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 Med10 PF09748.9 OQS07629.1 - 0.044 13.7 0.5 10 6.1 0.0 3.2 2 0 0 2 2 2 0 Transcription factor subunit Med10 of Mediator complex ASD2 PF08687.11 OQS07629.1 - 0.06 12.9 3.4 0.037 13.6 0.4 2.1 2 0 0 2 2 2 0 Apx/Shroom domain ASD2 HrpB7 PF09486.10 OQS07629.1 - 0.14 12.5 3.1 0.18 12.2 1.9 1.8 1 1 0 1 1 1 0 Bacterial type III secretion protein (HrpB7) DUF1515 PF07439.11 OQS07629.1 - 0.2 11.7 0.8 1.2 9.2 0.7 2.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1515) HalX PF08663.10 OQS07629.1 - 1 9.7 7.7 4.9 7.5 1.5 3.9 2 1 1 3 3 3 0 HalX domain DUF1090 PF06476.12 OQS07629.1 - 1.1 9.3 13.2 0.19 11.8 0.9 3.0 2 1 1 3 3 2 0 Protein of unknown function (DUF1090) MoaC PF01967.21 OQS07630.1 - 1.4e-53 180.6 0.1 1.7e-53 180.3 0.1 1.1 1 0 0 1 1 1 1 MoaC family ATP_bind_1 PF03029.17 OQS07631.1 - 3.5e-79 266.0 0.4 5.4e-79 265.4 0.4 1.3 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein Peptidase_M50 PF02163.22 OQS07631.1 - 9.6e-17 61.1 2.1 7.1e-16 58.2 2.1 2.2 1 1 0 1 1 1 1 Peptidase family M50 cobW PF02492.19 OQS07631.1 - 9.5e-08 31.8 0.1 2.4e-06 27.3 0.1 2.6 2 1 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain GTP_EFTU PF00009.27 OQS07631.1 - 2.7e-07 30.3 0.1 7.3e-07 28.9 0.1 1.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_16 PF13191.6 OQS07631.1 - 5.1e-05 23.7 0.0 0.00011 22.7 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain MMR_HSR1 PF01926.23 OQS07631.1 - 5.9e-05 23.1 0.0 0.00061 19.8 0.0 2.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase NACHT PF05729.12 OQS07631.1 - 0.00016 21.7 0.0 0.00034 20.6 0.0 1.5 1 0 0 1 1 1 1 NACHT domain FeoB_N PF02421.18 OQS07631.1 - 0.00032 20.3 0.1 0.0076 15.8 0.0 2.5 2 0 0 2 2 2 1 Ferrous iron transport protein B SRP54 PF00448.22 OQS07631.1 - 0.00066 19.4 0.0 0.017 14.7 0.0 2.3 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_33 PF13671.6 OQS07631.1 - 0.0014 18.7 0.1 0.009 16.2 0.1 2.5 3 1 0 3 3 2 1 AAA domain Ras PF00071.22 OQS07631.1 - 0.0032 17.1 0.2 0.91 9.1 0.1 2.6 2 0 0 2 2 2 1 Ras family AAA_24 PF13479.6 OQS07631.1 - 0.0033 17.2 0.0 0.0085 15.8 0.0 1.7 2 0 0 2 2 1 1 AAA domain AAA_22 PF13401.6 OQS07631.1 - 0.0052 17.1 0.0 0.021 15.1 0.0 2.1 2 0 0 2 2 1 1 AAA domain RsgA_GTPase PF03193.16 OQS07631.1 - 0.0066 16.4 0.0 6.6 6.6 0.0 3.3 4 0 0 4 4 4 0 RsgA GTPase NTPase_1 PF03266.15 OQS07631.1 - 0.0085 16.0 0.0 0.041 13.8 0.0 2.0 1 1 0 1 1 1 1 NTPase MeaB PF03308.16 OQS07631.1 - 0.014 14.4 0.1 0.79 8.6 0.0 2.8 2 1 1 3 3 3 0 Methylmalonyl Co-A mutase-associated GTPase MeaB PhoH PF02562.16 OQS07631.1 - 0.019 14.4 0.0 0.21 11.0 0.0 2.2 2 0 0 2 2 2 0 PhoH-like protein Arf PF00025.21 OQS07631.1 - 0.02 14.4 0.0 0.64 9.4 0.0 2.4 2 0 0 2 2 2 0 ADP-ribosylation factor family AAA_18 PF13238.6 OQS07631.1 - 0.021 15.4 0.1 0.077 13.5 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 OQS07631.1 - 0.024 14.4 0.0 0.048 13.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.22 OQS07631.1 - 0.025 13.8 0.0 0.048 12.8 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain Roc PF08477.13 OQS07631.1 - 0.031 14.5 0.4 0.61 10.3 0.0 2.9 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase ATPase_2 PF01637.18 OQS07631.1 - 0.049 13.5 0.1 0.25 11.2 0.0 2.0 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea Septin PF00735.18 OQS07631.1 - 0.053 12.8 0.0 0.62 9.3 0.0 2.4 2 0 0 2 2 2 0 Septin DUF2075 PF09848.9 OQS07631.1 - 0.058 12.6 0.7 0.077 12.2 0.0 1.6 2 0 0 2 2 1 0 Uncharacterized conserved protein (DUF2075) AAA_19 PF13245.6 OQS07631.1 - 0.063 13.6 0.0 0.14 12.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain SRPRB PF09439.10 OQS07631.1 - 0.066 12.6 0.0 0.37 10.2 0.0 2.0 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit AAA_31 PF13614.6 OQS07631.1 - 0.069 13.1 0.0 17 5.3 0.0 2.7 2 0 0 2 2 2 0 AAA domain PduV-EutP PF10662.9 OQS07631.1 - 0.07 12.9 1.7 0.71 9.6 0.0 2.9 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation G-alpha PF00503.20 OQS07631.1 - 0.11 11.6 0.1 1.5 7.9 0.0 2.3 2 1 0 2 2 2 0 G-protein alpha subunit Zeta_toxin PF06414.12 OQS07631.1 - 0.12 11.7 0.0 0.25 10.6 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin UvrD-helicase PF00580.21 OQS07631.1 - 0.13 11.8 0.1 0.55 9.7 0.0 1.9 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain Viral_helicase1 PF01443.18 OQS07631.1 - 0.16 11.7 0.0 0.43 10.3 0.0 1.7 2 0 0 2 2 1 0 Viral (Superfamily 1) RNA helicase TniB PF05621.11 OQS07631.1 - 0.25 10.7 1.3 0.79 9.1 0.0 2.3 3 0 0 3 3 3 0 Bacterial TniB protein LRR_8 PF13855.6 OQS07632.1 - 2e-09 37.0 1.8 5.4e-07 29.3 0.3 3.2 2 1 2 4 4 4 3 Leucine rich repeat LRR_4 PF12799.7 OQS07632.1 - 7.2e-08 32.6 5.0 0.004 17.5 0.1 3.6 2 1 1 3 3 3 2 Leucine Rich repeats (2 copies) Notch PF00066.17 OQS07632.1 - 0.023 15.1 17.8 0.093 13.2 17.8 2.1 1 1 0 1 1 1 0 LNR domain DUF5613 PF18467.1 OQS07633.1 - 0.55 10.7 4.2 0.36 11.3 0.3 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF5613) TbpB_A PF17484.2 OQS07633.1 - 0.64 10.8 7.0 2.1 9.1 7.0 1.9 1 1 0 1 1 1 0 N-Lobe handle Tf-binding protein B DDHD PF02862.17 OQS07633.1 - 0.69 10.0 7.9 0.82 9.8 7.9 1.1 1 0 0 1 1 1 0 DDHD domain COX16 PF14138.6 OQS07633.1 - 8.2 7.0 10.8 2 9.0 2.3 2.3 2 0 0 2 2 2 0 Cytochrome c oxidase assembly protein COX16 Hist_deacetyl PF00850.19 OQS07634.1 - 3.6e-61 207.3 0.3 5.2e-61 206.8 0.3 1.3 1 0 0 1 1 1 1 Histone deacetylase domain AMP-binding PF00501.28 OQS07635.1 - 1.5e-20 73.2 0.5 2.2e-20 72.7 0.5 1.4 1 1 0 1 1 1 1 AMP-binding enzyme DUF348 PF03990.14 OQS07635.1 - 0.16 11.7 0.9 27 4.6 0.0 3.3 3 0 0 3 3 3 0 G5-linked-Ubiquitin-like domain DAGK_cat PF00781.24 OQS07636.1 - 3.3e-22 78.4 0.0 5.9e-22 77.6 0.0 1.4 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain Tim54 PF11711.8 OQS07636.1 - 0.023 13.5 0.0 0.043 12.6 0.0 1.3 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Peptidase_C78 PF07910.13 OQS07637.1 - 3.2e-25 88.9 0.2 1.7e-24 86.5 0.0 2.0 1 1 1 2 2 2 1 Peptidase family C78 Cation_efflux PF01545.21 OQS07638.1 - 7.4e-45 153.1 3.8 1e-44 152.6 3.8 1.2 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 OQS07638.1 - 9.4e-22 76.9 5.3 3.9e-14 52.5 0.4 3.1 3 1 0 3 3 3 2 Dimerisation domain of Zinc Transporter PEX11 PF05648.14 OQS07639.1 - 3.7e-21 75.6 0.3 4.8e-21 75.2 0.3 1.2 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) START PF01852.19 OQS07641.1 - 1.7e-12 47.2 0.0 2.3e-12 46.8 0.0 1.1 1 0 0 1 1 1 1 START domain DUF3074 PF11274.8 OQS07641.1 - 0.00046 20.2 0.0 0.00073 19.6 0.0 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF3074) Frag1 PF10277.9 OQS07642.1 - 3.3e-12 46.4 22.2 5.3e-12 45.8 22.2 1.3 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family SdpI PF13630.6 OQS07642.1 - 0.032 14.4 2.9 0.032 14.4 2.9 3.2 4 1 0 4 4 4 0 SdpI/YhfL protein family zf-RING_2 PF13639.6 OQS07643.1 - 3.5e-12 46.5 8.8 3.5e-12 46.5 8.8 4.4 3 1 1 4 4 4 1 Ring finger domain zf-C3HC4_2 PF13923.6 OQS07643.1 - 1.1e-09 38.0 6.6 1.1e-09 38.0 6.6 3.6 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 OQS07643.1 - 1.1e-08 34.7 4.3 1.1e-08 34.7 4.3 4.9 3 2 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 OQS07643.1 - 3.1e-08 33.8 4.9 3.1e-08 33.8 4.9 3.8 4 2 1 5 5 5 1 RING-H2 zinc finger domain Prok-RING_4 PF14447.6 OQS07643.1 - 1.3e-07 31.3 5.6 1.3e-07 31.3 5.6 4.5 3 1 1 4 4 4 1 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 OQS07643.1 - 2.6e-07 30.4 5.8 2.6e-07 30.4 5.8 3.7 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OQS07643.1 - 1e-05 25.5 5.1 5.5e-05 23.1 5.1 2.4 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_11 PF17123.5 OQS07643.1 - 4.4e-05 23.1 5.2 4.4e-05 23.1 5.2 2.6 2 0 0 2 2 2 1 RING-like zinc finger zf-RING_5 PF14634.6 OQS07643.1 - 0.00029 20.7 6.6 0.00029 20.7 6.6 4.3 3 2 0 3 3 3 1 zinc-RING finger domain PH PF00169.29 OQS07644.1 - 3.5e-09 37.1 0.4 6.7e-09 36.2 0.4 1.4 1 0 0 1 1 1 1 PH domain PH_8 PF15409.6 OQS07644.1 - 0.021 15.1 0.1 0.045 14.0 0.1 1.5 1 0 0 1 1 1 0 Pleckstrin homology domain Mcp5_PH PF12814.7 OQS07644.1 - 2.2 8.4 4.8 23 5.1 0.2 2.8 1 1 1 2 2 2 0 Meiotic cell cortex C-terminal pleckstrin homology GSHPx PF00255.19 OQS07645.1 - 2e-26 91.7 0.1 2.6e-26 91.3 0.1 1.2 1 0 0 1 1 1 1 Glutathione peroxidase AhpC-TSA PF00578.21 OQS07645.1 - 0.025 14.5 0.1 0.051 13.5 0.0 1.6 2 0 0 2 2 2 0 AhpC/TSA family PGP_phosphatase PF09419.10 OQS07645.1 - 0.13 11.8 0.0 0.2 11.3 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial PGP phosphatase Nop14 PF04147.12 OQS07646.1 - 2.2e-184 615.2 64.3 4.2e-184 614.2 64.3 1.4 1 1 0 1 1 1 1 Nop14-like family 5_nucleotid_C PF02872.18 OQS07647.1 - 5.7e-14 52.6 0.0 6.8e-14 52.4 0.0 1.1 1 0 0 1 1 1 1 5'-nucleotidase, C-terminal domain TerD PF02342.18 OQS07647.1 - 0.012 15.1 0.0 0.018 14.6 0.0 1.2 1 0 0 1 1 1 0 TerD domain SAM_adeno_trans PF01887.16 OQS07647.1 - 0.1 12.0 0.0 0.13 11.7 0.0 1.2 1 0 0 1 1 1 0 S-adenosyl-l-methionine hydroxide adenosyltransferase PX PF00787.24 OQS07648.1 - 3.5e-10 39.9 0.1 4.9e-10 39.4 0.1 1.3 1 0 0 1 1 1 1 PX domain HEAT_2 PF13646.6 OQS07649.1 - 0.0024 18.2 0.1 0.056 13.8 0.1 2.4 2 0 0 2 2 2 1 HEAT repeats Retrotrans_gag PF03732.17 OQS07650.1 - 4.6e-10 39.6 0.1 2.6e-09 37.2 0.0 2.1 1 1 1 2 2 2 1 Retrotransposon gag protein SICA_alpha PF12887.7 OQS07650.1 - 0.022 14.6 0.0 0.045 13.6 0.0 1.5 1 0 0 1 1 1 0 SICA extracellular alpha domain SlyX PF04102.12 OQS07650.1 - 1.9 9.2 6.0 1.1 9.9 2.9 2.2 2 0 0 2 2 2 0 SlyX MAPEG PF01124.18 OQS07651.1 - 2e-18 66.5 0.0 2.7e-18 66.1 0.0 1.1 1 0 0 1 1 1 1 MAPEG family DUF3929 PF13066.6 OQS07652.1 - 0.061 13.4 1.3 0.082 13.0 0.6 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF3929) LtrA PF06772.11 OQS07654.1 - 0.00065 19.0 2.4 0.00089 18.6 2.4 1.2 1 0 0 1 1 1 1 Bacterial low temperature requirement A protein (LtrA) Glyco_trans_2_3 PF13632.6 OQS07656.1 - 2.4e-15 57.0 0.0 2.4e-15 57.0 0.0 2.0 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Cellulose_synt PF03552.14 OQS07656.1 - 2.6e-13 49.4 0.6 4.7e-13 48.5 0.4 1.4 1 1 0 1 1 1 1 Cellulose synthase Glyco_transf_21 PF13506.6 OQS07656.1 - 7.7e-05 22.2 0.4 0.0002 20.9 0.0 1.9 3 0 0 3 3 3 1 Glycosyl transferase family 21 Glyco_tranf_2_3 PF13641.6 OQS07656.1 - 0.00011 22.2 0.0 0.00015 21.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Gemin6 PF06372.12 OQS07657.1 - 1e-15 57.7 0.1 1.3e-15 57.3 0.1 1.0 1 0 0 1 1 1 1 Gemin6 protein SM-ATX PF14438.6 OQS07657.1 - 0.041 14.0 0.0 0.075 13.2 0.0 1.6 1 1 0 1 1 1 0 Ataxin 2 SM domain LSM14 PF12701.7 OQS07657.1 - 0.06 13.5 0.0 0.17 12.0 0.0 1.7 1 0 0 1 1 1 0 Scd6-like Sm domain DUF150_C PF17384.2 OQS07657.1 - 0.084 13.0 0.1 0.46 10.7 0.0 2.0 2 0 0 2 2 2 0 RimP C-terminal SH3 domain Atx10homo_assoc PF09759.9 OQS07658.1 - 0.0017 18.3 1.3 0.011 15.7 0.1 3.0 4 0 0 4 4 4 1 Spinocerebellar ataxia type 10 protein domain Arm PF00514.23 OQS07658.1 - 0.077 13.1 0.0 17 5.6 0.0 3.1 2 0 0 2 2 2 0 Armadillo/beta-catenin-like repeat Pkinase_Tyr PF07714.17 OQS07659.1 - 8.3e-23 81.0 0.0 9.7e-23 80.8 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OQS07659.1 - 1.5e-20 73.6 0.0 1.8e-20 73.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 OQS07659.1 - 0.0021 17.4 0.0 0.0022 17.4 0.0 1.1 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YchF-GTPase_C PF06071.13 OQS07659.1 - 0.013 15.6 0.0 0.022 15.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF933) Haspin_kinase PF12330.8 OQS07659.1 - 0.027 13.4 0.1 0.03 13.3 0.1 1.1 1 0 0 1 1 1 0 Haspin like kinase domain APH PF01636.23 OQS07659.1 - 0.13 12.1 0.0 0.13 12.1 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family CopG_antitoxin PF12441.8 OQS07660.1 - 1.1 9.8 4.2 12 6.6 0.2 3.0 2 1 1 3 3 3 0 CopG antitoxin of type II toxin-antitoxin system PIN_6 PF17146.4 OQS07660.1 - 9.3 6.8 8.0 3.9 8.1 2.0 2.9 2 1 1 3 3 3 0 PIN domain of ribonuclease DUF647 PF04884.14 OQS07661.1 - 9.8e-64 215.3 4.2 1.3e-63 214.9 4.2 1.1 1 0 0 1 1 1 1 Vitamin B6 photo-protection and homoeostasis DDE_Tnp_4 PF13359.6 OQS07662.1 - 9.5e-13 48.1 0.1 1.3e-12 47.6 0.1 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 OQS07662.1 - 4.7e-06 26.3 0.1 7.9e-06 25.6 0.1 1.4 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 OQS07662.1 - 0.044 13.4 0.0 0.062 12.9 0.0 1.2 1 0 0 1 1 1 0 Transposase DDE domain DUF3905 PF13045.6 OQS07662.1 - 0.054 13.5 0.2 0.087 12.8 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3905) LRR_4 PF12799.7 OQS07663.1 - 7.6e-05 23.0 18.0 0.18 12.3 5.7 3.6 2 1 1 3 3 3 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 OQS07663.1 - 0.0013 18.5 11.5 0.0027 17.4 8.8 2.6 1 1 1 2 2 2 2 Leucine rich repeat LRR_1 PF00560.33 OQS07663.1 - 0.78 10.5 7.9 36 5.5 1.5 4.2 3 2 0 3 3 3 0 Leucine Rich Repeat Ank_4 PF13637.6 OQS07664.1 - 1.8e-11 44.3 0.7 7.2e-06 26.5 0.0 2.3 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 OQS07664.1 - 3.6e-11 43.5 0.1 3.9e-11 43.4 0.1 1.1 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 OQS07664.1 - 4.3e-09 36.4 0.5 9.3e-06 25.9 0.4 3.1 3 0 0 3 3 3 1 Ankyrin repeat Ank_3 PF13606.6 OQS07664.1 - 4.4e-09 35.8 0.0 3.1e-05 24.0 0.1 3.2 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 OQS07664.1 - 3.6e-07 30.3 0.1 6e-07 29.6 0.1 1.3 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Dynein_C PF18199.1 OQS07665.1 - 4.8e-106 354.4 0.0 8.7e-106 353.6 0.0 1.4 1 0 0 1 1 1 1 Dynein heavy chain C-terminal domain AAA_9 PF12781.7 OQS07665.1 - 5.8e-88 293.7 0.8 7.6e-86 286.8 0.8 2.4 2 0 0 2 2 2 2 ATP-binding dynein motor region AAA_lid_11 PF18198.1 OQS07665.1 - 1.2e-54 184.6 0.1 2.1e-54 183.8 0.1 1.4 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 OQS07665.1 - 3.7e-46 156.1 0.0 5e-42 142.8 0.0 2.8 2 0 0 2 2 2 2 Dynein heavy chain region D6 P-loop domain Ank_2 PF12796.7 OQS07666.1 - 8.7e-86 282.6 19.9 4.9e-18 65.5 0.4 7.1 2 2 4 7 7 7 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQS07666.1 - 8.1e-61 201.7 13.9 1.5e-08 35.0 0.0 12.3 4 4 9 13 13 13 12 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQS07666.1 - 9.6e-58 185.4 9.4 0.0024 18.2 0.0 15.8 16 0 0 16 16 16 11 Ankyrin repeat Ank PF00023.30 OQS07666.1 - 3.2e-49 163.3 33.9 0.00012 22.4 0.2 14.1 15 0 0 15 15 15 11 Ankyrin repeat Ank_5 PF13857.6 OQS07666.1 - 3.6e-42 141.9 24.5 1.6e-05 25.0 0.1 11.5 4 4 9 13 13 13 13 Ankyrin repeats (many copies) Pkinase_Tyr PF07714.17 OQS07666.1 - 1.4e-39 135.9 0.0 2.6e-39 135.1 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OQS07666.1 - 5.9e-36 124.2 0.0 1.1e-35 123.3 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain VWA_3_C PF18571.1 OQS07666.1 - 0.00089 19.1 2.1 61 3.6 0.0 6.5 7 0 0 7 7 7 0 von Willebrand factor type A C-terminal domain Imm_superinfect PF14373.6 OQS07666.1 - 0.0015 18.4 2.7 1.1e+02 2.8 0.0 7.4 9 0 0 9 9 9 0 Superinfection immunity protein UFC1 PF08694.11 OQS07667.1 - 7.9e-82 272.4 0.1 8.9e-82 272.2 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-fold modifier-conjugating enzyme 1 UQ_con PF00179.26 OQS07667.1 - 0.0017 18.0 0.2 0.0037 16.9 0.2 1.5 1 1 0 1 1 1 1 Ubiquitin-conjugating enzyme Myb_DNA-bind_6 PF13921.6 OQS07667.1 - 0.022 15.0 0.0 0.038 14.3 0.0 1.3 1 0 0 1 1 1 0 Myb-like DNA-binding domain UEV PF05743.13 OQS07667.1 - 0.12 12.2 0.0 0.17 11.8 0.0 1.2 1 0 0 1 1 1 0 UEV domain DAO PF01266.24 OQS07668.1 - 6.6e-59 200.2 0.0 8.3e-59 199.9 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 OQS07668.1 - 7.8e-06 25.2 0.2 0.0012 18.0 0.1 2.1 2 0 0 2 2 2 2 FAD binding domain Thi4 PF01946.17 OQS07668.1 - 0.00017 20.9 0.0 0.00029 20.2 0.0 1.4 1 0 0 1 1 1 1 Thi4 family NAD_binding_8 PF13450.6 OQS07668.1 - 0.00094 19.4 0.9 0.0019 18.4 0.9 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.14 OQS07668.1 - 0.0013 17.7 0.1 0.035 13.0 0.1 2.1 2 0 0 2 2 2 1 Tryptophan halogenase NAD_binding_9 PF13454.6 OQS07668.1 - 0.0042 17.1 0.1 0.0097 15.9 0.1 1.6 1 0 0 1 1 1 1 FAD-NAD(P)-binding Shikimate_DH PF01488.20 OQS07668.1 - 0.011 15.7 0.0 0.14 12.2 0.1 2.4 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Pyr_redox_2 PF07992.14 OQS07668.1 - 0.012 14.9 1.7 0.1 11.8 0.6 2.6 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 OQS07668.1 - 0.015 15.8 0.7 0.067 13.7 0.2 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 OQS07668.1 - 0.044 12.8 0.3 0.17 10.9 0.1 1.9 2 0 0 2 2 2 0 Lycopene cyclase protein TPR_17 PF13431.6 OQS07673.1 - 2.2e-19 68.4 11.9 2.2e-06 27.6 1.2 5.7 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_1 PF00515.28 OQS07673.1 - 2.1e-16 59.0 15.8 0.0011 18.7 0.1 6.8 7 1 0 7 7 6 3 Tetratricopeptide repeat TPR_2 PF07719.17 OQS07673.1 - 5.4e-16 57.3 16.8 0.016 15.3 0.0 6.8 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_8 PF13181.6 OQS07673.1 - 2.1e-14 52.5 10.4 0.021 15.0 0.1 6.2 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_14 PF13428.6 OQS07673.1 - 2.2e-13 49.8 9.4 0.22 12.4 0.0 6.1 3 2 3 6 6 6 4 Tetratricopeptide repeat TPR_12 PF13424.6 OQS07673.1 - 1.5e-11 44.4 12.3 0.00034 20.9 0.3 4.9 3 2 1 4 4 4 3 Tetratricopeptide repeat TPR_19 PF14559.6 OQS07673.1 - 4.4e-10 39.9 9.2 8.3e-06 26.2 1.0 3.9 2 2 1 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 OQS07673.1 - 1.4e-09 37.5 6.8 4.3e-05 23.1 1.1 4.8 4 1 1 5 5 5 2 TPR repeat TPR_16 PF13432.6 OQS07673.1 - 1.7e-06 28.6 10.8 0.022 15.4 2.7 4.2 2 1 2 4 4 4 3 Tetratricopeptide repeat TPR_7 PF13176.6 OQS07673.1 - 3.3e-06 26.7 10.7 4.5 7.5 0.0 6.4 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_9 PF13371.6 OQS07673.1 - 3.3e-05 23.9 0.6 0.00076 19.6 0.0 3.1 2 1 1 3 3 3 1 Tetratricopeptide repeat Mad3_BUB1_I PF08311.12 OQS07673.1 - 0.00019 21.4 0.6 0.34 10.9 0.0 3.7 3 0 0 3 3 3 1 Mad3/BUB1 homology region 1 Suf PF05843.14 OQS07673.1 - 0.00057 20.0 1.0 0.00075 19.6 0.1 1.6 2 0 0 2 2 2 1 Suppressor of forked protein (Suf) TPR_10 PF13374.6 OQS07673.1 - 0.0011 18.7 26.0 1.2 9.1 0.0 6.9 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_15 PF13429.6 OQS07673.1 - 0.0028 16.9 0.9 0.033 13.4 0.3 2.5 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_MalT PF17874.1 OQS07673.1 - 0.0032 16.9 0.6 0.036 13.4 0.1 2.6 2 1 0 2 2 2 1 MalT-like TPR region NARP1 PF12569.8 OQS07673.1 - 0.0085 15.1 0.9 0.018 14.0 0.9 1.5 1 0 0 1 1 1 1 NMDA receptor-regulated protein 1 BTAD PF03704.17 OQS07673.1 - 0.017 15.5 0.1 0.061 13.8 0.1 2.0 1 0 0 1 1 1 0 Bacterial transcriptional activator domain ANAPC3 PF12895.7 OQS07673.1 - 0.32 11.3 9.6 1.9 8.8 3.2 3.7 2 1 2 4 4 3 0 Anaphase-promoting complex, cyclosome, subunit 3 XLF PF09302.11 OQS07674.1 - 0.11 12.6 0.4 16 5.6 0.2 2.1 2 0 0 2 2 2 0 XLF-Cernunnos, XRcc4-like factor, NHEJ component Ank_2 PF12796.7 OQS07675.1 - 1.1e-69 231.0 10.9 6.6e-19 68.3 0.1 5.8 2 1 3 6 6 6 6 Ankyrin repeats (3 copies) Ank PF00023.30 OQS07675.1 - 1.3e-63 208.8 23.2 8e-07 29.2 0.7 11.2 11 0 0 11 11 11 11 Ankyrin repeat Ank_4 PF13637.6 OQS07675.1 - 9.8e-57 188.6 18.1 5.2e-11 42.9 0.1 8.3 2 2 8 10 10 10 10 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQS07675.1 - 1.5e-55 178.6 10.9 0.00026 21.2 0.0 11.2 11 0 0 11 11 11 10 Ankyrin repeat Ank_5 PF13857.6 OQS07675.1 - 1.6e-42 143.0 10.2 1.8e-08 34.5 0.1 9.2 2 2 8 10 10 10 9 Ankyrin repeats (many copies) Arg_repressor PF01316.21 OQS07675.1 - 0.0086 15.8 8.1 30 4.4 0.3 6.2 7 1 0 7 7 7 0 Arginine repressor, DNA binding domain HEM4 PF02602.15 OQS07675.1 - 0.018 14.4 0.0 0.87 8.9 0.0 3.4 4 1 0 4 4 4 0 Uroporphyrinogen-III synthase HemD Methyltransf_16 PF10294.9 OQS07676.1 - 4.6e-26 91.6 0.0 5.8e-26 91.3 0.0 1.1 1 0 0 1 1 1 1 Lysine methyltransferase PrmA PF06325.13 OQS07676.1 - 0.16 11.4 0.0 0.22 10.9 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) 6PF2K PF01591.18 OQS07677.1 - 1.3e-63 214.3 0.1 1.9e-63 213.7 0.1 1.2 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 OQS07677.1 - 2.3e-36 125.3 0.0 3.8e-36 124.6 0.0 1.3 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.6 OQS07677.1 - 1.4e-06 28.5 0.0 6.1e-06 26.5 0.0 2.1 3 0 0 3 3 3 1 AAA domain AAA_18 PF13238.6 OQS07677.1 - 0.0028 18.2 0.0 0.0076 16.8 0.0 1.8 2 0 0 2 2 2 1 AAA domain KTI12 PF08433.10 OQS07677.1 - 0.0057 16.1 0.1 0.014 14.8 0.0 1.7 2 0 0 2 2 2 1 Chromatin associated protein KTI12 AAA PF00004.29 OQS07677.1 - 0.013 15.9 0.0 0.034 14.6 0.0 1.8 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 OQS07677.1 - 0.015 15.5 0.4 0.1 12.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain Torsin PF06309.11 OQS07677.1 - 0.032 14.3 0.0 0.17 12.0 0.0 2.1 2 0 0 2 2 2 0 Torsin LRR_6 PF13516.6 OQS07678.1 - 0.0023 17.9 3.7 0.32 11.2 0.1 3.5 3 0 0 3 3 3 2 Leucine Rich repeat RPAP3_C PF13877.6 OQS07678.1 - 0.017 15.6 0.7 0.16 12.5 0.0 2.8 3 1 0 3 3 3 0 Potential Monad-binding region of RPAP3 LRR_4 PF12799.7 OQS07678.1 - 0.049 14.1 0.6 0.049 14.1 0.6 3.5 1 1 3 4 4 4 0 Leucine Rich repeats (2 copies) PTR2 PF00854.21 OQS07679.1 - 2.1e-05 23.6 0.0 3.2e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 POT family HA PF03457.14 OQS07682.1 - 8.2e-21 74.1 0.4 3.5e-11 43.3 0.1 3.2 3 0 0 3 3 3 3 Helicase associated domain DUF3591 PF12157.8 OQS07683.1 - 1.4e-58 198.6 0.4 4.3e-58 197.0 0.2 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF3591) ANF_receptor PF01094.28 OQS07683.1 - 0.054 12.6 0.7 0.19 10.8 0.1 2.0 2 0 0 2 2 2 0 Receptor family ligand binding region F5_F8_type_C PF00754.25 OQS07684.1 - 0.0064 16.6 0.0 0.0069 16.5 0.0 1.0 1 0 0 1 1 1 1 F5/8 type C domain MCD PF05292.11 OQS07685.1 - 3.7e-91 305.2 0.0 5.7e-91 304.6 0.0 1.3 1 0 0 1 1 1 1 Malonyl-CoA decarboxylase C-terminal domain MCD_N PF17408.2 OQS07685.1 - 1.5e-09 37.8 0.5 3.7e-09 36.6 0.5 1.7 1 0 0 1 1 1 1 Malonyl-CoA decarboxylase N-terminal domain SIX1_SD PF16878.5 OQS07685.1 - 0.0057 17.2 0.0 0.032 14.8 0.0 2.2 2 0 0 2 2 2 1 Transcriptional regulator, SIX1, N-terminal SD domain TPR_1 PF00515.28 OQS07686.1 - 3.3e-14 52.0 1.8 0.0032 17.2 0.0 5.7 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_2 PF07719.17 OQS07686.1 - 9.3e-13 47.2 8.8 0.0058 16.6 0.0 6.4 7 1 0 7 7 6 3 Tetratricopeptide repeat TPR_8 PF13181.6 OQS07686.1 - 9.3e-12 44.2 5.0 0.001 19.1 0.0 5.8 6 1 0 6 6 5 3 Tetratricopeptide repeat TPR_19 PF14559.6 OQS07686.1 - 6.2e-11 42.6 8.8 2.4e-05 24.7 0.0 4.9 5 2 1 6 6 5 3 Tetratricopeptide repeat TPR_7 PF13176.6 OQS07686.1 - 4.1e-09 35.8 3.6 1.2 9.4 0.0 6.3 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_12 PF13424.6 OQS07686.1 - 4.2e-09 36.6 4.1 0.023 14.9 0.0 5.0 3 2 1 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 OQS07686.1 - 2.6e-08 34.0 4.0 0.19 12.6 0.0 5.4 4 2 2 6 6 5 2 Tetratricopeptide repeat TPR_17 PF13431.6 OQS07686.1 - 6.1e-07 29.4 0.3 2.1 8.9 0.0 4.8 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.6 OQS07686.1 - 9.8e-07 29.3 0.0 0.28 11.9 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat ANAPC3 PF12895.7 OQS07686.1 - 2.8e-05 24.3 0.2 0.0002 21.5 0.0 2.5 2 1 1 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 OQS07686.1 - 9.5e-05 22.8 3.2 1.1 10.1 0.0 4.9 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_9 PF13371.6 OQS07686.1 - 0.00042 20.4 0.0 0.065 13.4 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_15 PF13429.6 OQS07686.1 - 0.0028 16.9 0.2 1.3 8.2 0.0 3.4 3 1 1 4 4 4 1 Tetratricopeptide repeat NARP1 PF12569.8 OQS07686.1 - 0.0073 15.3 0.2 0.29 10.0 0.1 2.1 2 0 0 2 2 2 1 NMDA receptor-regulated protein 1 SHNi-TPR PF10516.9 OQS07686.1 - 0.0096 15.4 0.5 4.7 6.8 0.1 3.9 4 0 0 4 4 4 1 SHNi-TPR Clathrin PF00637.20 OQS07686.1 - 0.017 15.0 0.0 4.3 7.2 0.0 2.4 2 0 0 2 2 2 0 Region in Clathrin and VPS ChAPs PF09295.10 OQS07686.1 - 0.035 13.1 0.1 0.3 10.0 0.1 2.0 2 0 0 2 2 2 0 ChAPs (Chs5p-Arf1p-binding proteins) Sel1 PF08238.12 OQS07686.1 - 0.055 14.2 2.6 0.29 11.9 0.1 3.0 3 0 0 3 3 3 0 Sel1 repeat Exonuc_VII_S PF02609.16 OQS07686.1 - 0.11 12.6 2.6 7.3 6.7 0.5 3.2 2 0 0 2 2 2 0 Exonuclease VII small subunit WD40 PF00400.32 OQS07687.1 - 8.9e-25 86.5 20.6 4e-06 27.4 0.0 6.4 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OQS07687.1 - 3.8e-16 59.2 5.0 6.5e-07 29.6 0.2 4.2 1 1 2 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 OQS07687.1 - 3e-08 33.8 0.3 0.24 11.3 0.0 3.1 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A IKI3 PF04762.12 OQS07687.1 - 0.055 11.5 0.1 0.27 9.2 0.0 1.9 2 0 0 2 2 2 0 IKI3 family ATP-synt_ab PF00006.25 OQS07688.1 - 8.2e-12 45.2 0.0 1.1e-11 44.8 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.27 OQS07688.1 - 1.5e-05 25.3 0.2 4.1e-05 23.9 0.1 1.8 2 0 0 2 2 2 1 ATP synthase alpha/beta chain, C terminal domain SET PF00856.28 OQS07689.1 - 7e-07 29.8 0.0 0.024 15.0 0.0 2.2 1 1 1 2 2 2 2 SET domain DEAD PF00270.29 OQS07690.1 - 9.3e-49 165.6 0.0 1.5e-48 164.8 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OQS07690.1 - 7e-31 106.8 0.0 3.8e-30 104.5 0.0 2.2 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ERCC3_RAD25_C PF16203.5 OQS07690.1 - 6.9e-06 25.4 0.0 1.1e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase ResIII PF04851.15 OQS07690.1 - 1.4e-05 25.1 0.0 2.6e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Flavi_DEAD PF07652.14 OQS07690.1 - 0.11 12.4 0.0 0.3 11.1 0.0 1.6 1 0 0 1 1 1 0 Flavivirus DEAD domain Pkinase PF00069.25 OQS07691.1 - 1.1e-18 67.5 0.0 1.3e-18 67.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQS07691.1 - 1.2e-15 57.5 0.0 1.5e-15 57.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OQS07691.1 - 0.13 11.1 0.0 0.29 9.9 0.0 1.5 2 0 0 2 2 2 0 Fungal protein kinase zf-RING_2 PF13639.6 OQS07692.1 - 3.7e-12 46.4 10.3 9.8e-12 45.0 10.3 1.8 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 OQS07692.1 - 8.4e-09 35.1 9.5 1.7e-08 34.1 9.5 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 OQS07692.1 - 6.8e-07 28.9 6.2 1.6e-06 27.8 6.2 1.7 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4 PF00097.25 OQS07692.1 - 1.7e-06 27.8 7.7 3.8e-06 26.7 7.7 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OQS07692.1 - 3.3e-06 27.0 5.6 1.1e-05 25.4 5.7 2.0 1 1 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 OQS07692.1 - 8e-06 25.6 9.3 1.5e-05 24.8 9.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 OQS07692.1 - 1.4e-05 25.3 11.3 1.4e-05 25.3 11.3 2.1 2 1 0 2 2 1 1 RING-H2 zinc finger domain PX PF00787.24 OQS07692.1 - 1.9e-05 24.6 1.1 4e-05 23.6 0.6 1.6 2 0 0 2 2 2 1 PX domain zf-RING_5 PF14634.6 OQS07692.1 - 0.00017 21.4 8.4 0.00036 20.4 8.4 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 OQS07692.1 - 0.0038 17.2 9.4 0.0054 16.8 8.3 1.9 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-Nse PF11789.8 OQS07692.1 - 0.0059 16.4 3.7 0.022 14.6 3.1 2.1 2 0 0 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit zinc_ribbon_16 PF17034.5 OQS07692.1 - 0.044 14.0 6.6 0.081 13.1 6.6 1.4 1 0 0 1 1 1 0 Zinc-ribbon like family Prok-RING_4 PF14447.6 OQS07692.1 - 0.054 13.4 10.5 0.12 12.2 10.5 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-C3H2C3 PF17122.5 OQS07692.1 - 0.08 13.0 7.0 0.21 11.7 7.0 1.8 1 1 0 1 1 1 0 Zinc-finger Zn_ribbon_17 PF17120.5 OQS07692.1 - 0.099 12.3 9.6 0.21 11.2 9.6 1.5 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type Prok-RING_1 PF14446.6 OQS07692.1 - 1.2 9.1 7.2 1.6 8.7 1.6 2.7 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 zf-RING_4 PF14570.6 OQS07692.1 - 6.4 6.7 9.5 13 5.7 9.5 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain WASH-7_C PF14746.6 OQS07693.1 - 9.1e-12 45.0 0.6 9.5e-12 45.0 0.6 1.0 1 0 0 1 1 1 1 WASH complex subunit 7, C-terminal RRM_3 PF08777.11 OQS07693.1 - 0.053 13.6 0.7 0.065 13.3 0.7 1.2 1 0 0 1 1 1 0 RNA binding motif zf-RING_2 PF13639.6 OQS07694.1 - 1.9e-10 40.9 6.2 4.2e-10 39.8 6.2 1.6 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 OQS07694.1 - 7e-09 35.8 9.5 8.6e-09 35.6 8.1 1.9 2 1 0 2 2 1 1 RING-H2 zinc finger domain PX PF00787.24 OQS07694.1 - 1.5e-08 34.6 0.0 2.9e-08 33.7 0.0 1.5 1 0 0 1 1 1 1 PX domain zf-C3HC4 PF00097.25 OQS07694.1 - 8.3e-08 32.0 7.0 1.6e-07 31.1 7.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 OQS07694.1 - 9.7e-07 28.5 8.5 3.8e-06 26.6 8.5 2.0 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 OQS07694.1 - 3.4e-06 26.7 3.6 3.4e-06 26.7 3.6 2.1 2 0 0 2 2 2 1 RING-like zinc finger zf-ANAPC11 PF12861.7 OQS07694.1 - 1.4e-05 25.0 6.0 4.6e-05 23.4 6.0 1.9 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.6 OQS07694.1 - 3.9e-05 23.5 7.2 7.8e-05 22.5 7.2 1.5 1 0 0 1 1 1 1 zinc-RING finger domain FANCL_C PF11793.8 OQS07694.1 - 0.00012 22.2 3.7 0.002 18.3 4.2 2.5 2 1 0 2 2 2 1 FANCL C-terminal domain zf-RING_UBOX PF13445.6 OQS07694.1 - 0.00039 20.4 4.0 0.00079 19.4 4.0 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 OQS07694.1 - 0.0046 16.8 6.4 0.015 15.1 6.4 1.9 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 OQS07694.1 - 0.012 15.3 3.2 0.028 14.2 3.2 1.6 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-Nse PF11789.8 OQS07694.1 - 0.022 14.6 2.4 0.041 13.7 2.4 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit NCD1 PF04904.13 OQS07694.1 - 0.04 13.9 1.5 2.3 8.3 0.2 2.4 1 1 1 2 2 2 0 NAB conserved region 1 (NCD1) PHD PF00628.29 OQS07694.1 - 0.043 13.7 6.3 0.089 12.7 6.3 1.6 1 0 0 1 1 1 0 PHD-finger Zn_ribbon_17 PF17120.5 OQS07694.1 - 0.049 13.3 4.4 0.12 12.0 4.4 1.7 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-C3H2C3 PF17122.5 OQS07694.1 - 0.15 12.2 7.4 0.47 10.5 7.4 1.9 1 1 0 1 1 1 0 Zinc-finger Prok-RING_4 PF14447.6 OQS07694.1 - 0.24 11.3 6.8 0.98 9.3 7.0 1.9 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 RINGv PF12906.7 OQS07694.1 - 0.39 10.9 6.1 1.1 9.4 6.1 1.8 1 1 0 1 1 1 0 RING-variant domain eIF3_N PF09440.10 OQS07695.1 - 5.6e-39 133.6 0.6 1.5e-38 132.2 0.7 1.7 2 0 0 2 2 2 1 eIF3 subunit 6 N terminal domain PCI PF01399.27 OQS07695.1 - 0.0033 17.9 0.1 0.0091 16.5 0.1 1.8 1 0 0 1 1 1 1 PCI domain TPR_3 PF07720.12 OQS07695.1 - 0.47 10.5 3.9 1.3 9.0 3.9 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat Ank_4 PF13637.6 OQS07696.1 - 2.5e-10 40.6 2.0 0.045 14.4 0.1 4.5 5 0 0 5 5 5 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 OQS07696.1 - 1.1e-07 32.3 0.2 0.002 18.7 0.1 3.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OQS07696.1 - 2.1e-05 24.7 3.2 0.00077 19.7 0.1 3.9 3 1 3 6 6 6 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQS07696.1 - 0.00051 20.3 0.5 42 5.2 0.1 5.2 5 0 0 5 5 5 1 Ankyrin repeat AA_permease PF00324.21 OQS07697.1 - 1.5e-11 43.6 13.5 1.5e-11 43.6 13.5 1.5 2 0 0 2 2 2 1 Amino acid permease AA_permease_C PF13906.6 OQS07697.1 - 2e-11 43.8 6.8 2e-11 43.8 6.8 3.0 3 0 0 3 3 3 1 C-terminus of AA_permease AA_permease_2 PF13520.6 OQS07697.1 - 2.9e-10 39.6 12.8 2.9e-10 39.6 12.8 2.2 1 1 1 2 2 2 1 Amino acid permease Macro PF01661.21 OQS07698.1 - 6.1e-15 55.3 0.0 9.6e-15 54.7 0.0 1.3 1 0 0 1 1 1 1 Macro domain Glyco_trans_1_2 PF13524.6 OQS07698.1 - 0.014 15.8 0.0 8.4 6.9 0.0 2.8 3 0 0 3 3 3 0 Glycosyl transferases group 1 HTH_Tnp_1_2 PF13022.6 OQS07698.1 - 0.051 13.7 0.1 12 6.1 0.0 2.5 2 0 0 2 2 2 0 Helix-turn-helix of insertion element transposase Arg_decarb_HB PF17810.1 OQS07698.1 - 0.28 11.4 0.6 5.1 7.4 0.1 2.3 2 0 0 2 2 2 0 Arginine decarboxylase helical bundle domain Sec66 PF09802.9 OQS07699.1 - 1.6e-15 57.1 4.0 2.4e-15 56.6 4.0 1.2 1 0 0 1 1 1 1 Preprotein translocase subunit Sec66 DUF4833 PF16117.5 OQS07701.1 - 3.3e-38 130.8 0.1 6.1e-38 130.0 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4833) DUF2076 PF09849.9 OQS07701.1 - 0.017 15.2 2.0 0.017 15.2 2.0 1.4 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) OmpH PF03938.14 OQS07701.1 - 0.093 13.1 6.5 0.16 12.3 6.5 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Ead_Ea22 PF13935.6 OQS07701.1 - 0.11 13.2 1.1 0.19 12.4 1.1 1.4 1 0 0 1 1 1 0 Ead/Ea22-like protein LCD1 PF09798.9 OQS07701.1 - 0.13 10.7 4.6 0.18 10.3 4.6 1.1 1 0 0 1 1 1 0 DNA damage checkpoint protein Fmp27_WPPW PF10359.9 OQS07701.1 - 0.4 9.5 3.9 2.5 6.8 2.2 2.0 2 0 0 2 2 2 0 RNA pol II promoter Fmp27 protein domain Atg14 PF10186.9 OQS07701.1 - 1.2 8.2 4.4 1.6 7.8 4.4 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 TEX13 PF15186.6 OQS07701.1 - 2 8.1 8.8 3.3 7.4 8.8 1.2 1 0 0 1 1 1 0 Testis-expressed sequence 13 protein family SRP19 PF01922.17 OQS07702.1 - 9.3e-25 87.4 0.1 6e-24 84.8 0.0 2.3 2 0 0 2 2 2 1 SRP19 protein DUF4296 PF14129.6 OQS07702.1 - 0.0011 19.6 2.6 0.73 10.5 0.4 2.7 2 0 0 2 2 2 2 Domain of unknown function (DUF4296) Forkhead_N PF08430.12 OQS07702.1 - 2.9 8.5 44.6 12 6.5 44.6 2.1 1 0 0 1 1 1 0 Forkhead N-terminal region PWI PF01480.17 OQS07703.1 - 4.2e-14 52.6 0.4 7.2e-14 51.9 0.4 1.3 1 0 0 1 1 1 1 PWI domain Rad10 PF03834.14 OQS07704.1 - 5.1e-33 113.5 0.1 9.7e-33 112.6 0.0 1.5 2 0 0 2 2 2 1 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) HHH_5 PF14520.6 OQS07704.1 - 1.1e-05 26.0 0.0 3.4e-05 24.4 0.0 1.7 2 0 0 2 2 2 1 Helix-hairpin-helix domain HHH PF00633.23 OQS07704.1 - 0.0019 18.0 0.0 0.0041 16.9 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix motif HHH_2 PF12826.7 OQS07704.1 - 0.0025 17.9 0.0 0.0042 17.1 0.0 1.4 1 0 0 1 1 1 1 Helix-hairpin-helix motif SNARE PF05739.19 OQS07705.1 - 0.04 13.9 1.4 0.092 12.8 0.1 2.3 2 0 0 2 2 2 0 SNARE domain DUF2533 PF10752.9 OQS07705.1 - 0.066 13.7 0.1 0.066 13.7 0.1 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF2533) FliG_N PF14842.6 OQS07705.1 - 0.56 10.8 5.4 1.2 9.7 0.3 2.5 2 0 0 2 2 2 0 FliG N-terminal domain PHD PF00628.29 OQS07706.1 - 2.4e-13 49.8 23.0 3.7e-09 36.3 2.8 4.0 3 1 1 4 4 4 2 PHD-finger PWWP PF00855.17 OQS07706.1 - 6.3e-13 48.9 0.0 1.7e-12 47.6 0.0 1.7 1 0 0 1 1 1 1 PWWP domain zf-HC5HC2H PF13771.6 OQS07706.1 - 1.2e-07 31.8 12.9 0.0019 18.4 2.9 2.7 2 1 0 2 2 2 2 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.6 OQS07706.1 - 6.2e-07 29.6 13.7 0.001 19.2 0.5 3.2 2 1 0 3 3 3 2 PHD-zinc-finger like domain FANCL_C PF11793.8 OQS07706.1 - 0.017 15.3 2.7 0.017 15.3 2.7 3.8 4 1 0 4 4 4 0 FANCL C-terminal domain PHD_2 PF13831.6 OQS07706.1 - 0.15 11.7 22.3 0.21 11.2 0.7 4.6 4 0 0 4 4 4 0 PHD-finger DHC_N1 PF08385.12 OQS07707.1 - 9.4e-189 628.7 3.8 9.4e-189 628.7 3.8 3.1 3 0 0 3 3 3 1 Dynein heavy chain, N-terminal region 1 AAA_6 PF12774.7 OQS07707.1 - 5.4e-138 459.4 6.2 2.8e-75 253.3 0.0 4.0 4 0 0 4 4 4 2 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 OQS07707.1 - 2.6e-112 375.8 19.8 2.6e-112 375.8 19.8 3.6 3 1 1 4 4 4 1 Dynein heavy chain, N-terminal region 2 AAA_7 PF12775.7 OQS07707.1 - 1.8e-66 223.1 0.6 1.1e-59 201.0 0.1 3.8 3 0 0 3 3 3 3 P-loop containing dynein motor region Dynein_AAA_lid PF17852.1 OQS07707.1 - 2.4e-25 89.1 0.2 1.1e-24 87.0 0.2 2.3 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_5 PF07728.14 OQS07707.1 - 4.6e-21 75.3 0.8 2.2e-08 34.2 0.0 5.8 4 2 0 4 4 4 3 AAA domain (dynein-related subfamily) AAA_30 PF13604.6 OQS07707.1 - 8.1e-08 32.2 1.0 0.011 15.5 0.0 3.6 3 0 0 3 3 3 2 AAA domain AAA_16 PF13191.6 OQS07707.1 - 1.8e-07 31.7 0.0 0.00097 19.6 0.0 4.4 3 0 0 3 3 3 1 AAA ATPase domain AAA_19 PF13245.6 OQS07707.1 - 2.6e-07 31.1 1.9 0.0026 18.1 0.0 4.3 4 0 0 4 4 3 1 AAA domain AAA PF00004.29 OQS07707.1 - 2.3e-06 28.1 0.1 0.073 13.5 0.0 4.1 4 0 0 4 4 3 2 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 OQS07707.1 - 1.5e-05 25.5 0.1 0.039 14.5 0.0 4.6 4 0 0 4 4 4 1 AAA domain NACHT PF05729.12 OQS07707.1 - 2.9e-05 24.0 0.1 0.072 13.0 0.0 3.5 3 0 0 3 3 3 1 NACHT domain T2SSE PF00437.20 OQS07707.1 - 5.6e-05 22.3 0.1 0.041 12.9 0.0 2.9 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_22 PF13401.6 OQS07707.1 - 0.00011 22.5 0.4 0.26 11.5 0.0 4.3 4 0 0 4 4 4 1 AAA domain RNA_helicase PF00910.22 OQS07707.1 - 0.00028 21.2 0.6 2.6 8.5 0.0 4.4 4 0 0 4 4 3 1 RNA helicase SRP54 PF00448.22 OQS07707.1 - 0.00039 20.1 1.0 0.44 10.1 0.1 3.7 3 0 0 3 3 3 1 SRP54-type protein, GTPase domain TsaE PF02367.17 OQS07707.1 - 0.001 19.1 0.2 0.82 9.7 0.0 3.7 3 0 0 3 3 3 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE Sigma54_activ_2 PF14532.6 OQS07707.1 - 0.0012 18.9 0.0 0.18 11.9 0.0 3.4 3 0 0 3 3 3 1 Sigma-54 interaction domain AAA_28 PF13521.6 OQS07707.1 - 0.0013 19.0 0.1 5 7.3 0.0 3.8 3 0 0 3 3 3 1 AAA domain AAA_33 PF13671.6 OQS07707.1 - 0.0032 17.6 0.4 0.69 10.1 0.0 3.9 4 0 0 4 4 3 1 AAA domain ABC_tran PF00005.27 OQS07707.1 - 0.0043 17.6 0.0 0.086 13.4 0.0 3.0 2 0 0 2 2 2 1 ABC transporter ATP_bind_1 PF03029.17 OQS07707.1 - 0.009 15.8 0.4 22 4.7 0.0 4.3 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein Sigma54_activat PF00158.26 OQS07707.1 - 0.0091 15.7 0.0 5.7 6.6 0.0 2.7 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_14 PF13173.6 OQS07707.1 - 0.015 15.4 0.0 0.2 11.7 0.0 3.0 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 OQS07707.1 - 0.029 13.9 0.8 13 5.3 0.0 3.2 3 0 0 3 3 3 0 AAA domain BCDHK_Adom3 PF10436.9 OQS07707.1 - 0.033 14.0 0.1 0.033 14.0 0.1 3.3 4 1 0 4 4 3 0 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase Roc PF08477.13 OQS07707.1 - 0.067 13.4 2.1 0.5 10.6 0.0 3.6 4 0 0 4 4 2 0 Ras of Complex, Roc, domain of DAPkinase ATPase PF06745.13 OQS07707.1 - 0.12 11.7 0.3 1.8 7.9 0.0 3.0 3 0 0 3 3 3 0 KaiC Mg_chelatase PF01078.21 OQS07707.1 - 0.15 11.4 0.0 15 4.9 0.0 2.8 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI AAA_24 PF13479.6 OQS07707.1 - 0.4 10.4 9.2 2 8.1 0.0 4.3 5 0 0 5 5 4 0 AAA domain UvrD-helicase PF00580.21 OQS07707.1 - 0.58 9.6 0.0 0.58 9.6 0.0 5.1 6 2 0 6 6 3 0 UvrD/REP helicase N-terminal domain CbiA PF01656.23 OQS07707.1 - 6.1 6.9 5.9 63 3.6 0.1 4.7 5 0 0 5 5 4 0 CobQ/CobB/MinD/ParA nucleotide binding domain ApbA_C PF08546.11 OQS07708.1 - 1.7e-08 34.7 0.0 4.4e-08 33.4 0.0 1.7 1 1 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal Pirin_C_2 PF17954.1 OQS07708.1 - 0.097 12.9 0.0 0.19 11.9 0.0 1.5 1 0 0 1 1 1 0 Quercetinase C-terminal cupin domain EF-hand_7 PF13499.6 OQS07709.1 - 1.1e-13 51.5 7.0 2.5e-08 34.3 3.6 3.3 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 OQS07709.1 - 8.5e-12 43.7 9.7 0.00015 21.1 0.8 3.9 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.6 OQS07709.1 - 3.2e-09 36.0 8.1 0.0034 17.2 0.4 4.1 4 0 0 4 4 4 3 EF-hand domain EF-hand_5 PF13202.6 OQS07709.1 - 1.9e-08 33.4 7.0 0.00026 20.3 0.7 3.6 3 0 0 3 3 3 3 EF hand EF-hand_8 PF13833.6 OQS07709.1 - 0.00072 19.3 10.8 0.17 11.8 0.3 3.6 3 0 0 3 3 3 2 EF-hand domain pair Ribosomal_S21 PF01165.20 OQS07710.1 - 2.4e-07 30.3 2.2 3.7e-07 29.8 2.2 1.3 1 0 0 1 1 1 1 Ribosomal protein S21 DUF4709 PF15821.5 OQS07710.1 - 0.011 16.0 0.5 0.016 15.5 0.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4709) ANAPC15 PF15243.6 OQS07710.1 - 0.03 14.7 0.0 0.042 14.2 0.0 1.2 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 15 TFIID_NTD2 PF04494.15 OQS07710.1 - 0.052 13.8 0.3 0.063 13.5 0.3 1.1 1 0 0 1 1 1 0 WD40 associated region in TFIID subunit, NTD2 domain baeRF_family10 PF18854.1 OQS07710.1 - 0.076 13.3 1.1 0.081 13.2 1.1 1.1 1 0 0 1 1 1 0 Bacterial archaeo-eukaryotic release factor family 10 EF-hand_5 PF13202.6 OQS07711.1 - 5.5e-11 41.5 0.0 1.6e-05 24.2 0.0 2.2 2 0 0 2 2 2 2 EF hand EF-hand_1 PF00036.32 OQS07711.1 - 9.6e-11 40.4 0.9 3.2e-05 23.2 0.1 2.4 2 1 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 OQS07711.1 - 1.1e-09 38.5 0.7 1.6e-09 38.1 0.7 1.3 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 OQS07711.1 - 1.4e-08 34.0 0.0 0.0074 16.1 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.6 OQS07711.1 - 6.7e-08 32.3 1.7 2.2e-06 27.4 0.1 2.9 1 1 2 3 3 3 2 EF-hand domain pair SPARC_Ca_bdg PF10591.9 OQS07711.1 - 0.046 14.0 0.1 0.15 12.4 0.1 1.7 1 1 0 1 1 1 0 Secreted protein acidic and rich in cysteine Ca binding region PMBR PF09373.10 OQS07711.1 - 0.13 12.5 1.6 0.24 11.6 0.0 2.2 3 0 0 3 3 3 0 Pseudomurein-binding repeat Trypsin PF00089.26 OQS07712.1 - 1.3e-32 113.4 0.1 1.4e-32 113.3 0.1 1.0 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 OQS07712.1 - 0.00068 20.6 0.0 0.001 20.0 0.0 1.3 1 0 0 1 1 1 1 Trypsin-like peptidase domain Pkinase PF00069.25 OQS07713.1 - 4.5e-29 101.6 0.0 7.2e-29 101.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQS07713.1 - 1.4e-25 90.1 0.0 2.2e-25 89.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase C2 PF00168.30 OQS07713.1 - 1.9e-11 44.2 0.0 3.5e-08 33.7 0.0 2.5 2 0 0 2 2 2 2 C2 domain Kinase-like PF14531.6 OQS07713.1 - 0.00048 19.5 0.0 0.00079 18.8 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 OQS07713.1 - 0.0068 15.8 0.1 0.012 15.0 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family DUF3973 PF13119.6 OQS07713.1 - 0.14 12.2 0.6 0.49 10.5 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3973) Oxidored_FMN PF00724.20 OQS07714.1 - 5e-86 289.1 0.0 5.7e-86 288.9 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Mito_carr PF00153.27 OQS07715.1 - 6.2e-65 215.2 1.8 4.3e-21 74.6 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein Ricin_B_lectin PF00652.22 OQS07715.1 - 3.2e-05 24.2 1.0 5.9e-05 23.3 1.0 1.5 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain Sugar_tr PF00083.24 OQS07716.1 - 4.7e-41 141.1 36.4 6.3e-27 94.5 9.6 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 OQS07716.1 - 1.9e-26 92.9 68.1 5e-24 84.9 36.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily CCSMST1 PF15013.6 OQS07716.1 - 0.047 13.8 0.1 2.1 8.6 0.0 2.5 2 0 0 2 2 2 0 CCSMST1 family AbiJ_NTD5 PF18865.1 OQS07716.1 - 0.11 12.3 0.0 0.2 11.5 0.0 1.3 1 0 0 1 1 1 0 AbiJ N-terminal domain 5 DUF1634 PF07843.11 OQS07716.1 - 0.14 12.2 12.5 1.9 8.6 0.2 3.6 3 1 0 3 3 3 0 Protein of unknown function (DUF1634) T4SS_CagC PF16943.5 OQS07716.1 - 0.33 11.1 3.2 4.1 7.6 0.1 3.1 3 0 0 3 3 3 0 Cag pathogenicity island, type IV secretory system Pkinase PF00069.25 OQS07717.1 - 4.8e-54 183.5 0.0 6.1e-54 183.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQS07717.1 - 1.6e-53 181.7 0.0 1.9e-53 181.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 OQS07717.1 - 0.00028 20.3 0.4 0.00052 19.4 0.1 1.6 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 OQS07717.1 - 0.0011 17.8 0.0 0.0017 17.2 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 OQS07717.1 - 0.0021 17.4 0.0 0.0029 17.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Prominin PF05478.11 OQS07717.1 - 0.0067 14.5 3.6 0.011 13.8 3.6 1.2 1 0 0 1 1 1 1 Prominin Haspin_kinase PF12330.8 OQS07717.1 - 0.093 11.7 0.0 0.18 10.7 0.0 1.6 1 1 0 1 1 1 0 Haspin like kinase domain DMA PF03474.14 OQS07719.1 - 0.0006 19.4 0.0 0.0011 18.6 0.0 1.4 1 0 0 1 1 1 1 DMRTA motif zf-CCCH PF00642.24 OQS07719.1 - 0.0032 17.3 9.7 1.8 8.5 0.4 3.3 3 0 0 3 3 3 3 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_5 PF18384.1 OQS07719.1 - 0.0076 16.3 1.4 1.8 8.8 0.3 2.3 2 0 0 2 2 2 2 Unkempt Zinc finger domain 1 (Znf1) zf_CCCH_4 PF18345.1 OQS07719.1 - 0.33 11.1 9.0 5.9 7.1 2.2 3.1 3 0 0 3 3 3 0 Zinc finger domain zf-CCCH_3 PF15663.5 OQS07719.1 - 0.34 11.1 2.6 3 8.1 2.6 2.1 1 1 0 1 1 1 0 Zinc-finger containing family PP2C PF00481.21 OQS07721.1 - 5.8e-16 58.9 0.0 6.2e-15 55.5 0.0 1.9 1 1 0 1 1 1 1 Protein phosphatase 2C ELYS PF13934.6 OQS07722.1 - 2.2e-09 37.6 1.2 2.2e-09 37.6 1.2 1.9 2 0 0 2 2 2 1 Nuclear pore complex assembly DUF5522 PF17653.1 OQS07723.1 - 9.1e-21 73.6 4.7 2.2e-20 72.3 4.7 1.7 1 0 0 1 1 1 1 Family of unknown function (DUF5522) Diphthami_syn_2 PF01902.17 OQS07723.1 - 4.8e-11 42.6 0.0 7.8e-11 41.9 0.0 1.2 1 0 0 1 1 1 1 Diphthamide synthase EamA PF00892.20 OQS07724.1 - 1.1e-20 74.2 39.2 1.1e-15 58.0 17.5 2.1 2 0 0 2 2 2 2 EamA-like transporter family TPT PF03151.16 OQS07724.1 - 0.0023 17.3 7.9 0.0023 17.3 7.9 2.7 1 1 1 2 2 2 1 Triose-phosphate Transporter family SLATT_1 PF18181.1 OQS07724.1 - 0.014 15.3 0.3 0.038 13.9 0.3 1.7 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain 1 SLC35F PF06027.12 OQS07724.1 - 0.51 9.8 19.7 0.26 10.7 2.9 2.4 2 0 0 2 2 2 0 Solute carrier family 35 RseC_MucC PF04246.12 OQS07724.1 - 3 7.8 16.9 0.25 11.3 2.2 3.3 2 1 1 3 3 3 0 Positive regulator of sigma(E), RseC/MucC DUF2070 PF09843.9 OQS07724.1 - 8 4.6 24.6 0.94 7.7 10.4 2.0 1 1 1 2 2 2 0 Predicted membrane protein (DUF2070) Peptidase_A22B PF04258.13 OQS07725.1 - 2.5e-62 211.0 9.6 4.2e-62 210.2 9.6 1.2 1 0 0 1 1 1 1 Signal peptide peptidase PA PF02225.22 OQS07725.1 - 0.0006 19.8 0.1 0.0018 18.2 0.1 1.8 1 0 0 1 1 1 1 PA domain DUF2070 PF09843.9 OQS07725.1 - 4.3 5.5 16.1 6.7 4.9 16.1 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) UPF0176_N PF17773.1 OQS07728.1 - 2.2e-20 72.8 0.0 4.8e-20 71.7 0.0 1.6 1 0 0 1 1 1 1 UPF0176 acylphosphatase like domain Rhodanese PF00581.20 OQS07728.1 - 2.1e-13 50.7 0.0 4.3e-13 49.7 0.0 1.6 1 0 0 1 1 1 1 Rhodanese-like domain Rhodanese_C PF12368.8 OQS07728.1 - 1.3e-12 47.9 5.4 2.9e-12 46.8 5.4 1.6 1 0 0 1 1 1 1 Rhodanase C-terminal zf-C3HC4_3 PF13920.6 OQS07728.1 - 4.4 7.2 9.1 6.5 6.7 2.1 2.3 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) TFA2_Winged_2 PF18121.1 OQS07729.1 - 0.0021 17.7 0.0 2 8.2 0.0 2.2 2 0 0 2 2 2 2 TFA2 Winged helix domain 2 ESSS PF10183.9 OQS07729.1 - 0.012 15.8 0.6 6.1 7.1 0.2 2.7 2 1 0 2 2 2 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) DUF4326 PF14216.6 OQS07729.1 - 0.031 15.0 0.0 2.3 9.0 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4326) RNA_GG_bind PF10258.9 OQS07729.1 - 0.13 12.3 0.0 0.29 11.2 0.0 1.5 1 0 0 1 1 1 0 PHAX RNA-binding domain GntR PF00392.21 OQS07729.1 - 0.14 11.8 3.0 9.2 6.0 0.2 2.3 2 0 0 2 2 2 0 Bacterial regulatory proteins, gntR family Cytochrom_C PF00034.21 OQS07730.1 - 5.9e-13 49.8 0.1 8.6e-13 49.3 0.1 1.3 1 1 0 1 1 1 1 Cytochrome c Cytochrome_CBB3 PF13442.6 OQS07730.1 - 1.2e-06 28.7 1.8 5e-06 26.7 1.8 1.8 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C550 PF14495.6 OQS07730.1 - 0.013 15.2 1.4 0.022 14.5 1.4 1.8 1 1 0 1 1 1 0 Cytochrome c-550 domain Cytochrome_P460 PF16694.5 OQS07730.1 - 0.11 12.9 0.3 6.2 7.2 0.1 2.1 2 0 0 2 2 2 0 Cytochrome P460 DUF4965 PF16335.5 OQS07731.1 - 0.034 13.8 0.0 0.06 13.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4965) AAA PF00004.29 OQS07733.1 - 5.2e-17 62.5 0.0 1e-16 61.5 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 OQS07733.1 - 9.5e-05 22.2 0.0 0.00021 21.1 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 OQS07733.1 - 0.0019 18.6 0.0 0.0093 16.4 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain AAA_28 PF13521.6 OQS07733.1 - 0.019 15.2 0.0 0.044 14.0 0.0 1.6 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 OQS07733.1 - 0.033 14.5 0.0 0.088 13.1 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 OQS07733.1 - 0.034 14.3 0.0 0.072 13.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 OQS07733.1 - 0.097 12.7 0.0 0.27 11.2 0.0 1.9 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 OQS07733.1 - 0.1 13.2 0.0 0.78 10.3 0.0 2.1 2 0 0 2 2 2 0 AAA domain Glyco_trans_1_2 PF13524.6 OQS07733.1 - 0.1 13.0 0.0 0.48 10.9 0.0 2.1 3 0 0 3 3 3 0 Glycosyl transferases group 1 AAA_11 PF13086.6 OQS07733.1 - 0.12 12.1 0.0 0.2 11.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 OQS07733.1 - 0.13 12.2 0.0 0.24 11.4 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE TIP49 PF06068.13 OQS07733.1 - 0.18 11.0 0.0 0.28 10.3 0.0 1.2 1 0 0 1 1 1 0 TIP49 P-loop domain Metallophos PF00149.28 OQS07734.1 - 1.4e-22 81.2 0.1 2.1e-22 80.6 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase RabGAP-TBC PF00566.18 OQS07735.1 - 9.7e-05 22.1 2.3 0.00018 21.3 0.0 2.0 2 0 0 2 2 2 1 Rab-GTPase-TBC domain DctP PF03480.13 OQS07735.1 - 0.13 11.5 0.1 0.43 9.9 0.0 1.7 2 0 0 2 2 2 0 Bacterial extracellular solute-binding protein, family 7 Asparaginase_2 PF01112.18 OQS07736.1 - 4.1e-10 39.2 0.0 4.1e-10 39.2 0.0 1.1 1 0 0 1 1 1 1 Asparaginase Asparaginase_2 PF01112.18 OQS07737.1 - 6.6e-73 245.4 1.0 7.8e-73 245.2 1.0 1.0 1 0 0 1 1 1 1 Asparaginase HMG_box PF00505.19 OQS07738.1 - 1.8e-33 114.8 12.6 7.2e-20 71.2 7.5 2.8 2 0 0 2 2 2 2 HMG (high mobility group) box HMG_box_2 PF09011.10 OQS07738.1 - 2.8e-19 69.5 13.0 6.1e-12 46.0 6.7 2.7 2 0 0 2 2 2 2 HMG-box domain UPF0242 PF06785.11 OQS07738.1 - 7.5e-05 22.9 11.9 7.5e-05 22.9 11.9 2.5 2 2 0 2 2 2 1 Uncharacterised protein family (UPF0242) N-terminus NPV_P10 PF05531.12 OQS07738.1 - 0.0035 17.8 0.9 0.0035 17.8 0.9 2.7 2 1 1 3 3 3 1 Nucleopolyhedrovirus P10 protein Prominin PF05478.11 OQS07738.1 - 0.018 13.0 7.2 0.03 12.3 7.2 1.2 1 0 0 1 1 1 0 Prominin Phe_tRNA-synt_N PF02912.18 OQS07738.1 - 0.039 13.9 1.7 0.039 13.9 1.7 2.5 2 1 0 2 2 2 0 Aminoacyl tRNA synthetase class II, N-terminal domain WDCP PF15390.6 OQS07738.1 - 0.69 8.2 9.6 0.022 13.2 3.2 1.6 2 0 0 2 2 2 0 WD repeat and coiled-coil-containing protein family DHC PF09626.10 OQS07738.1 - 1.6 9.6 5.9 1.8 9.4 0.1 2.9 2 1 1 3 3 3 0 Dihaem cytochrome c Uds1 PF15456.6 OQS07738.1 - 2.1 8.5 13.6 0.094 12.9 7.0 2.0 2 0 0 2 2 2 0 Up-regulated During Septation GIT_CC PF16559.5 OQS07738.1 - 3.3 7.6 9.0 1 9.2 2.1 2.5 2 0 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor SlyX PF04102.12 OQS07738.1 - 7.2 7.3 15.4 0.2 12.3 2.0 3.2 3 0 0 3 3 3 0 SlyX DUF1664 PF07889.12 OQS07738.1 - 7.9 6.5 9.7 2.1 8.4 5.5 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) Takusan PF04822.13 OQS07739.1 - 0.00069 19.5 0.2 0.0027 17.6 0.2 2.0 1 0 0 1 1 1 1 Takusan DUF29 PF01724.16 OQS07739.1 - 0.18 12.1 2.3 0.26 11.5 0.9 1.9 2 0 0 2 2 2 0 Domain of unknown function DUF29 Jacalin PF01419.17 OQS07740.1 - 0.025 14.5 0.1 0.63 10.0 0.0 2.2 2 0 0 2 2 2 0 Jacalin-like lectin domain Rtt106_N PF18215.1 OQS07740.1 - 0.052 13.3 1.1 0.61 9.9 0.1 2.8 3 0 0 3 3 3 0 Histone chaperone Rtt106 N-terminal domain zf-Tim10_DDP PF02953.15 OQS07741.1 - 1.6e-17 62.9 5.8 2.1e-17 62.5 5.8 1.2 1 0 0 1 1 1 1 Tim10/DDP family zinc finger Flagellin_N PF00669.20 OQS07741.1 - 0.019 15.1 1.5 0.021 14.9 1.5 1.1 1 0 0 1 1 1 0 Bacterial flagellin N-terminal helical region Vicilin_N PF04702.12 OQS07741.1 - 0.07 13.0 9.2 0.083 12.7 9.2 1.2 1 0 0 1 1 1 0 Vicilin N terminal region MatE PF01554.18 OQS07742.1 - 3e-44 150.5 36.9 4.8e-25 88.1 16.1 2.7 3 0 0 3 3 3 2 MatE DUF953 PF06110.11 OQS07744.1 - 8.8e-31 106.0 0.0 1.3e-13 50.6 0.0 4.2 3 1 1 4 4 4 3 Eukaryotic protein of unknown function (DUF953) AhpC-TSA PF00578.21 OQS07744.1 - 0.00038 20.4 0.0 0.12 12.3 0.0 2.4 2 0 0 2 2 2 2 AhpC/TSA family EF-hand_7 PF13499.6 OQS07745.1 - 5.7e-20 71.5 10.7 7.9e-10 39.0 2.2 4.1 4 0 0 4 4 4 3 EF-hand domain pair EF-hand_1 PF00036.32 OQS07745.1 - 7.2e-20 69.0 9.6 2.2e-07 29.9 0.4 4.7 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.6 OQS07745.1 - 5.3e-19 66.5 4.6 1.3e-07 30.9 0.3 4.6 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 OQS07745.1 - 4.4e-15 54.4 5.9 7.2e-05 22.1 0.2 3.7 3 0 0 3 3 3 3 EF hand EF-hand_8 PF13833.6 OQS07745.1 - 2.4e-14 52.9 8.2 1e-07 31.7 1.2 4.6 3 1 1 4 4 4 4 EF-hand domain pair EF-hand_9 PF14658.6 OQS07745.1 - 0.00067 19.9 0.1 0.24 11.8 0.2 3.3 3 0 0 3 3 3 1 EF-hand domain Mlo PF03094.15 OQS07745.1 - 4.9 5.4 9.3 0.093 11.1 2.1 1.8 2 1 0 2 2 2 0 Mlo family OTU PF02338.19 OQS07746.1 - 0.0088 16.5 0.1 0.55 10.7 0.1 2.4 1 1 0 1 1 1 1 OTU-like cysteine protease Peptidase_S9 PF00326.21 OQS07746.1 - 0.075 12.5 0.0 0.15 11.6 0.0 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase family MMR_HSR1 PF01926.23 OQS07747.1 - 2.8e-19 69.3 0.0 1.4e-18 67.0 0.0 1.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 OQS07747.1 - 2.2e-06 27.7 0.7 0.0013 18.7 0.1 2.2 2 0 0 2 2 2 2 RsgA GTPase FeoB_N PF02421.18 OQS07747.1 - 3e-05 23.6 0.1 6.3e-05 22.5 0.1 1.7 1 1 0 1 1 1 1 Ferrous iron transport protein B GTP_EFTU PF00009.27 OQS07747.1 - 0.0011 18.5 0.3 0.33 10.5 0.1 2.6 2 1 0 2 2 2 2 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 OQS07747.1 - 0.0014 18.7 2.2 0.034 14.2 0.4 2.5 2 1 0 3 3 3 1 Dynamin family Septin PF00735.18 OQS07747.1 - 0.014 14.7 0.0 0.03 13.6 0.0 1.5 2 0 0 2 2 2 0 Septin IIGP PF05049.13 OQS07747.1 - 0.025 13.7 0.5 0.11 11.6 0.5 1.9 1 1 0 1 1 1 0 Interferon-inducible GTPase (IIGP) SRPRB PF09439.10 OQS07747.1 - 0.062 12.7 0.0 0.13 11.6 0.0 1.5 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Roc PF08477.13 OQS07747.1 - 0.086 13.1 0.1 0.18 12.0 0.1 1.6 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase AAA_29 PF13555.6 OQS07747.1 - 0.1 12.3 0.1 0.22 11.3 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Phos_pyr_kin PF08543.12 OQS07749.1 - 2.3e-19 69.7 0.0 2.9e-19 69.4 0.0 1.1 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase PfkB PF00294.24 OQS07749.1 - 6.2e-11 42.1 0.0 1.8e-10 40.6 0.0 1.7 1 1 0 1 1 1 1 pfkB family carbohydrate kinase DUF1837 PF08878.11 OQS07749.1 - 0.09 12.6 0.0 0.16 11.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1837) Carb_kinase PF01256.17 OQS07749.1 - 0.11 11.9 0.0 0.43 10.0 0.0 1.9 1 1 0 1 1 1 0 Carbohydrate kinase PCI PF01399.27 OQS07750.1 - 3.6e-15 56.4 0.2 2e-14 54.0 0.1 2.3 3 0 0 3 3 3 1 PCI domain RPN6_N PF18055.1 OQS07750.1 - 0.0094 16.3 0.2 0.048 14.0 0.1 2.2 1 1 1 2 2 2 1 26S proteasome regulatory subunit RPN6 N-terminal domain TPR_7 PF13176.6 OQS07750.1 - 0.093 12.8 0.0 17 5.7 0.0 3.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.6 OQS07750.1 - 0.14 13.1 0.0 29 5.8 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat Hydantoinase_B PF02538.14 OQS07751.1 - 6.4e-109 364.7 0.0 8.4e-109 364.3 0.0 1.2 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.18 OQS07751.1 - 2.7e-97 325.5 0.0 5.9e-97 324.4 0.0 1.6 1 0 0 1 1 1 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.13 OQS07751.1 - 1.5e-59 200.7 1.1 1.5e-57 194.1 0.1 2.5 2 0 0 2 2 2 2 Hydantoinase/oxoprolinase N-terminal region Spermine_synth PF01564.17 OQS07752.1 - 0.0057 16.1 0.0 0.0086 15.5 0.0 1.2 1 0 0 1 1 1 1 Spermine/spermidine synthase domain MotY_N PF18393.1 OQS07752.1 - 0.11 12.6 0.0 0.16 12.1 0.0 1.4 1 1 0 1 1 1 0 MotY N-terminal domain TGS PF02824.21 OQS07753.1 - 0.15 12.1 0.0 0.28 11.3 0.0 1.4 1 0 0 1 1 1 0 TGS domain Ephrin_rec_like PF07699.13 OQS07754.1 - 0.0016 18.1 33.8 0.0054 16.5 5.2 6.1 4 1 0 5 5 5 2 Putative ephrin-receptor like NCD3G PF07562.14 OQS07754.1 - 0.0039 17.1 0.3 0.0039 17.1 0.3 5.1 4 1 1 5 5 5 1 Nine Cysteines Domain of family 3 GPCR Exo_endo_phos PF03372.23 OQS07755.1 - 3.2e-20 72.6 0.0 7e-11 42.1 0.0 2.2 2 0 0 2 2 2 2 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.6 OQS07755.1 - 0.012 15.4 0.0 0.039 13.8 0.0 1.9 2 0 0 2 2 2 0 Endonuclease-reverse transcriptase LELP1 PF15042.6 OQS07755.1 - 0.12 12.7 1.8 0.19 12.1 1.8 1.2 1 0 0 1 1 1 0 Late cornified envelope-like proline-rich protein 1 Kazal_1 PF00050.21 OQS07756.1 - 7.7e-06 25.8 5.3 7.7e-06 25.8 5.3 1.7 2 0 0 2 2 2 1 Kazal-type serine protease inhibitor domain Kazal_2 PF07648.15 OQS07756.1 - 7.8e-06 25.9 3.9 7.8e-06 25.9 3.9 2.3 1 1 1 2 2 2 1 Kazal-type serine protease inhibitor domain Orn_Arg_deC_N PF02784.16 OQS07757.1 - 2e-14 53.6 0.0 3e-13 49.7 0.0 2.2 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Actin PF00022.19 OQS07758.1 - 4.1e-58 196.9 0.0 4.4e-58 196.8 0.0 1.0 1 0 0 1 1 1 1 Actin DUF4282 PF14110.6 OQS07759.1 - 0.012 16.3 0.7 0.012 16.3 0.7 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4282) Ac81 PF05820.11 OQS07759.1 - 0.096 12.2 0.2 0.096 12.2 0.2 2.0 2 0 0 2 2 2 0 Baculoviridae AC81 DUF4293 PF14126.6 OQS07759.1 - 0.57 10.4 8.3 0.41 10.9 5.5 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4293) EamA PF00892.20 OQS07760.1 - 5.9e-21 75.1 33.1 2e-11 44.2 11.8 2.1 2 0 0 2 2 2 2 EamA-like transporter family SLC35F PF06027.12 OQS07760.1 - 5.9e-08 32.6 14.9 1e-07 31.8 14.9 1.5 1 1 0 1 1 1 1 Solute carrier family 35 PUNUT PF16913.5 OQS07760.1 - 0.00012 21.5 11.5 0.00012 21.5 11.5 2.1 1 1 1 2 2 2 1 Purine nucleobase transmembrane transport TPT PF03151.16 OQS07760.1 - 0.00075 18.9 14.0 0.0011 18.4 14.0 1.3 1 0 0 1 1 1 1 Triose-phosphate Transporter family Sugar_transport PF06800.12 OQS07760.1 - 0.0047 16.3 2.2 0.0047 16.3 2.2 3.2 3 1 0 3 3 3 2 Sugar transport protein DUF2206 PF09971.9 OQS07760.1 - 1.3 7.7 14.1 1.8 7.2 6.6 2.2 2 0 0 2 2 2 0 Predicted membrane protein (DUF2206) HIT PF01230.23 OQS07761.1 - 6.7e-10 39.6 0.0 1.3e-09 38.6 0.0 1.4 1 0 0 1 1 1 1 HIT domain CwfJ_C_1 PF04677.15 OQS07761.1 - 0.0068 16.3 0.0 0.55 10.1 0.0 2.2 1 1 1 2 2 2 2 Protein similar to CwfJ C-terminus 1 PH PF00169.29 OQS07762.1 - 2.7e-10 40.7 0.1 2.9e-09 37.4 0.1 2.5 2 0 0 2 2 2 1 PH domain Glycos_transf_2 PF00535.26 OQS07762.1 - 0.00026 20.9 0.0 0.015 15.1 0.0 2.4 2 0 0 2 2 2 1 Glycosyl transferase family 2 PH_8 PF15409.6 OQS07762.1 - 0.0029 17.9 1.6 0.057 13.7 1.6 2.3 1 1 0 1 1 1 1 Pleckstrin homology domain PH_11 PF15413.6 OQS07762.1 - 0.028 14.8 4.5 0.044 14.2 3.0 2.2 2 1 0 2 2 2 0 Pleckstrin homology domain zf-C6H2 PF15801.5 OQS07762.1 - 0.036 14.4 15.8 0.049 13.9 9.0 3.1 2 0 0 2 2 2 0 zf-MYND-like zinc finger, mRNA-binding Glyco_tranf_2_3 PF13641.6 OQS07762.1 - 0.13 12.2 0.0 0.26 11.1 0.0 1.5 1 0 0 1 1 1 0 Glycosyltransferase like family 2 CcmH PF03918.14 OQS07762.1 - 0.45 9.8 4.5 24 4.2 0.1 3.2 2 1 1 3 3 3 0 Cytochrome C biogenesis protein PH PF00169.29 OQS07763.1 - 4.7e-09 36.7 0.0 1.2e-08 35.4 0.0 1.8 1 0 0 1 1 1 1 PH domain Glycos_transf_2 PF00535.26 OQS07763.1 - 1.9e-06 27.8 0.0 0.0037 17.1 0.0 2.6 2 0 0 2 2 2 2 Glycosyl transferase family 2 zf-C6H2 PF15801.5 OQS07763.1 - 0.00094 19.4 10.0 0.00094 19.4 10.0 2.9 2 0 0 2 2 2 1 zf-MYND-like zinc finger, mRNA-binding PH_11 PF15413.6 OQS07763.1 - 0.0018 18.7 0.1 0.0044 17.4 0.1 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain PH_8 PF15409.6 OQS07763.1 - 0.011 16.0 0.8 0.087 13.1 0.8 2.2 1 1 0 1 1 1 0 Pleckstrin homology domain Glyco_tranf_2_3 PF13641.6 OQS07763.1 - 0.022 14.6 0.0 0.12 12.3 0.0 2.1 2 0 0 2 2 2 0 Glycosyltransferase like family 2 LETM1 PF07766.13 OQS07764.1 - 1.2e-45 155.9 0.2 1.2e-45 155.9 0.2 2.3 2 0 0 2 2 2 1 LETM1-like protein EF-hand_1 PF00036.32 OQS07764.1 - 8.8e-10 37.4 1.6 0.00087 18.7 0.0 3.1 3 0 0 3 3 3 2 EF hand EF-hand_7 PF13499.6 OQS07764.1 - 2.7e-09 37.3 3.0 6.1e-08 33.0 0.3 3.7 3 1 1 4 4 4 2 EF-hand domain pair EF-hand_8 PF13833.6 OQS07764.1 - 4.2e-09 36.1 0.9 2e-08 33.9 0.1 2.7 3 1 0 3 3 3 1 EF-hand domain pair EF-hand_5 PF13202.6 OQS07764.1 - 2.6e-08 33.0 4.3 0.00076 18.9 0.1 3.0 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.6 OQS07764.1 - 2.3e-07 30.2 0.5 0.022 14.7 0.0 3.2 3 0 0 3 3 3 2 EF-hand domain DUF5109 PF17134.4 OQS07764.1 - 0.048 13.6 0.0 0.14 12.1 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF5109) SPARC_Ca_bdg PF10591.9 OQS07764.1 - 0.054 13.8 0.2 0.054 13.8 0.2 3.1 4 0 0 4 4 4 0 Secreted protein acidic and rich in cysteine Ca binding region Rotamase PF00639.21 OQS07764.1 - 0.54 11.2 7.3 6 7.9 2.8 2.9 2 0 0 2 2 2 0 PPIC-type PPIASE domain LETM1 PF07766.13 OQS07765.1 - 4e-48 164.1 2.2 4e-48 164.1 2.2 2.0 2 0 0 2 2 2 1 LETM1-like protein ADIP PF11559.8 OQS07765.1 - 0.031 14.4 1.1 0.031 14.4 1.1 2.5 3 0 0 3 3 3 0 Afadin- and alpha -actinin-Binding Phage_holin_3_6 PF07332.11 OQS07766.1 - 0.008 16.2 0.1 0.008 16.2 0.1 1.9 2 0 0 2 2 2 1 Putative Actinobacterial Holin-X, holin superfamily III DUF3487 PF11990.8 OQS07766.1 - 0.037 13.9 0.5 0.037 13.9 0.5 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3487) UDPGT PF00201.18 OQS07766.1 - 0.098 11.4 0.1 0.14 10.9 0.1 1.2 1 0 0 1 1 1 0 UDP-glucoronosyl and UDP-glucosyl transferase IspA PF04279.15 OQS07766.1 - 0.5 10.5 10.8 0.082 13.1 1.2 2.1 2 0 0 2 2 2 0 Intracellular septation protein A Pkinase PF00069.25 OQS07768.1 - 3.9e-37 128.0 0.7 7.1e-36 123.9 0.7 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQS07768.1 - 4.8e-15 55.6 0.1 8.7e-15 54.7 0.1 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OQS07768.1 - 0.0088 14.9 0.0 0.013 14.3 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 OQS07768.1 - 0.011 15.0 0.0 0.024 13.9 0.0 1.4 1 1 0 1 1 1 0 Kinase-like Pkinase PF00069.25 OQS07769.1 - 4.5e-50 170.5 0.0 8.3e-49 166.3 0.0 2.4 1 1 1 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQS07769.1 - 2.5e-49 167.9 0.0 5e-49 166.9 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Ank_2 PF12796.7 OQS07769.1 - 6.9e-45 151.5 15.6 9.9e-18 64.5 0.2 5.9 2 1 5 7 7 7 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQS07769.1 - 1.8e-36 124.0 4.3 6.4e-08 33.0 0.0 8.0 4 3 5 9 9 9 7 Ankyrin repeats (many copies) Ank PF00023.30 OQS07769.1 - 6.5e-28 95.9 20.3 8.1e-06 26.1 0.0 8.3 8 2 0 8 8 8 5 Ankyrin repeat Ank_3 PF13606.6 OQS07769.1 - 1.7e-27 92.4 10.8 0.0001 22.5 0.0 10.5 10 1 0 10 10 10 5 Ankyrin repeat Ank_5 PF13857.6 OQS07769.1 - 4e-24 84.4 8.1 2.5e-07 30.8 0.0 7.8 4 3 4 8 8 8 5 Ankyrin repeats (many copies) Pkinase_fungal PF17667.1 OQS07769.1 - 0.015 14.1 0.0 0.032 13.0 0.0 1.5 1 0 0 1 1 1 0 Fungal protein kinase PK_C PF02887.16 OQS07769.1 - 0.024 14.9 0.0 0.16 12.2 0.0 2.2 2 0 0 2 2 2 0 Pyruvate kinase, alpha/beta domain SHQ1 PF04925.15 OQS07769.1 - 0.061 12.9 1.3 0.11 12.1 0.5 1.9 2 0 0 2 2 2 0 SHQ1 protein DZR PF12773.7 OQS07769.1 - 0.073 13.1 12.1 0.16 12.1 12.1 1.6 1 0 0 1 1 1 0 Double zinc ribbon zf-C2HC5 PF06221.13 OQS07769.1 - 0.41 10.7 10.2 0.24 11.4 2.8 2.7 2 0 0 2 2 2 0 Putative zinc finger motif, C2HC5-type SMC_N PF02463.19 OQS07771.1 - 6.7e-69 231.7 0.0 1.3e-68 230.8 0.0 1.6 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 OQS07771.1 - 3.9e-20 72.3 0.5 1.8e-19 70.2 0.1 2.4 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 OQS07771.1 - 1.1e-11 45.1 4.2 1.7e-05 24.8 0.2 3.1 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system Spc7 PF08317.11 OQS07771.1 - 6.6e-07 28.5 106.4 0.0088 15.0 8.0 6.4 3 2 3 6 6 6 5 Spc7 kinetochore protein AAA_23 PF13476.6 OQS07771.1 - 1.7e-05 25.4 37.3 1.7e-05 25.4 37.3 6.7 2 2 1 3 3 1 1 AAA domain AAA_29 PF13555.6 OQS07771.1 - 4.7e-05 23.0 0.0 0.00011 21.8 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain PspA_IM30 PF04012.12 OQS07771.1 - 0.001 18.7 20.7 0.001 18.7 20.7 6.6 4 2 1 6 6 4 1 PspA/IM30 family ATG16 PF08614.11 OQS07771.1 - 0.0022 18.2 108.7 0.057 13.6 10.9 6.9 2 2 5 7 7 6 3 Autophagy protein 16 (ATG16) MscS_porin PF12795.7 OQS07771.1 - 0.0064 16.1 30.3 0.0064 16.1 30.3 6.2 2 2 3 5 5 4 2 Mechanosensitive ion channel porin domain Baculo_PEP_C PF04513.12 OQS07771.1 - 0.0068 16.5 4.9 0.0068 16.5 4.9 7.3 3 2 4 7 7 7 2 Baculovirus polyhedron envelope protein, PEP, C terminus KASH_CCD PF14662.6 OQS07771.1 - 0.0085 15.9 13.7 0.0085 15.9 13.7 6.7 2 2 4 7 7 7 1 Coiled-coil region of CCDC155 or KASH Fib_alpha PF08702.10 OQS07771.1 - 0.011 15.9 11.1 0.011 15.9 11.1 6.8 4 2 1 7 7 7 0 Fibrinogen alpha/beta chain family ABC_tran PF00005.27 OQS07771.1 - 0.32 11.5 0.0 0.32 11.5 0.0 6.3 3 2 1 4 4 3 0 ABC transporter DUF1664 PF07889.12 OQS07771.1 - 0.54 10.3 76.3 0.092 12.8 3.0 9.1 5 2 7 12 12 12 0 Protein of unknown function (DUF1664) DASH_Dam1 PF08653.10 OQS07771.1 - 0.72 9.7 6.9 6.4 6.7 0.1 5.4 4 0 0 4 4 4 0 DASH complex subunit Dam1 APG6_N PF17675.1 OQS07771.1 - 3 8.4 113.3 0.12 12.9 18.0 7.5 2 2 5 7 7 7 0 Apg6 coiled-coil region Phage_tail_NK PF16532.5 OQS07771.1 - 9.1 5.9 8.4 1.1 8.9 0.3 2.9 3 0 0 3 3 3 0 Sf6-type phage tail needle knob or tip of some Caudovirales G6PD_C PF02781.16 OQS07772.1 - 8.1e-63 212.3 0.0 8.9e-63 212.2 0.0 1.0 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.22 OQS07773.1 - 1.3e-53 182.2 0.0 1.8e-53 181.8 0.0 1.2 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, NAD binding domain G6PD_C PF02781.16 OQS07773.1 - 7.2e-51 173.1 0.0 1.1e-50 172.5 0.0 1.3 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain Glyco_hydro_72 PF03198.14 OQS07773.1 - 0.031 13.5 0.0 0.051 12.8 0.0 1.2 1 0 0 1 1 1 0 Glucanosyltransferase Glutaredoxin PF00462.24 OQS07775.1 - 2.4e-08 34.1 0.0 4.9e-08 33.1 0.0 1.6 1 0 0 1 1 1 1 Glutaredoxin DUF3449 PF11931.8 OQS07776.1 - 2.6e-24 86.0 0.2 2.8e-24 85.9 0.2 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3449) DUF3449 PF11931.8 OQS07777.1 - 9e-60 201.6 0.4 1.8e-57 194.2 0.0 2.6 2 1 1 3 3 3 2 Domain of unknown function (DUF3449) SF3A3 PF16837.5 OQS07777.1 - 5e-25 87.8 0.3 3.5e-24 85.1 0.1 2.4 2 0 0 2 2 2 1 Pre-mRNA-splicing factor SF3A3, of SF3a complex, Prp9 SF3a60_bindingd PF12108.8 OQS07777.1 - 2.4e-09 36.9 0.6 2.4e-09 36.9 0.6 2.2 2 0 0 2 2 2 1 Splicing factor SF3a60 binding domain zf-met PF12874.7 OQS07777.1 - 3.7e-09 36.7 6.6 6.2e-09 36.0 1.8 2.5 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 OQS07777.1 - 1.2e-08 35.0 1.5 1.2e-08 35.0 1.5 2.5 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 OQS07777.1 - 0.001 19.4 4.0 0.004 17.5 0.2 2.8 2 1 0 2 2 2 1 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.6 OQS07777.1 - 0.091 13.6 3.5 13 7.0 0.5 2.9 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C4H2 PF10146.9 OQS07777.1 - 0.18 12.1 2.0 0.2 12.0 0.0 1.9 2 0 0 2 2 2 0 Zinc finger-containing protein Desulfoferrod_N PF06397.12 OQS07777.1 - 0.26 10.9 1.2 0.59 9.8 1.2 1.5 1 0 0 1 1 1 0 Desulfoferrodoxin, N-terminal domain zn-ribbon_14 PF16503.5 OQS07777.1 - 2.7 7.6 5.1 0.92 9.1 0.5 2.3 2 0 0 2 2 2 0 Zinc-ribbon HECT PF00632.25 OQS07778.1 - 1.8e-55 188.6 0.0 2.7e-55 188.1 0.0 1.1 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) DUF434 PF04256.12 OQS07778.1 - 0.039 13.6 0.0 15 5.4 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF434) Pkinase PF00069.25 OQS07779.1 - 6.9e-07 28.9 0.0 6.9e-07 28.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQS07779.1 - 6.8e-06 25.5 0.1 7.7e-06 25.4 0.1 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase DUF2162 PF09930.9 OQS07780.1 - 0.0026 17.2 3.1 0.003 17.0 3.1 1.2 1 0 0 1 1 1 1 Predicted transporter (DUF2162) Radial_spoke PF04712.12 OQS07781.1 - 2e-09 37.0 0.0 6.3e-06 25.4 0.0 2.2 2 0 0 2 2 2 2 Radial spokehead-like protein Dicer_dimer PF03368.14 OQS07782.1 - 1.4e-19 70.1 0.1 3.2e-19 68.9 0.1 1.7 1 0 0 1 1 1 1 Dicer dimerisation domain Helicase_C PF00271.31 OQS07782.1 - 3.1e-10 40.4 0.0 1.1e-09 38.6 0.0 1.9 1 1 0 1 1 1 1 Helicase conserved C-terminal domain ADK PF00406.22 OQS07783.1 - 5e-43 146.8 0.0 8.8e-43 146.0 0.0 1.4 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 OQS07783.1 - 3.4e-33 115.0 1.7 4.2e-33 114.7 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 OQS07783.1 - 0.00015 22.3 0.0 0.00032 21.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 OQS07783.1 - 0.00092 19.4 0.0 0.0046 17.1 0.0 2.3 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 OQS07783.1 - 0.017 15.4 0.9 0.052 13.9 0.2 2.1 2 0 0 2 2 2 0 AAA domain ThiF PF00899.21 OQS07784.1 - 3e-49 167.6 0.3 5.9e-31 107.7 0.0 2.0 2 0 0 2 2 2 2 ThiF family E1_FCCH PF16190.5 OQS07784.1 - 2.9e-23 81.9 0.3 6.6e-23 80.7 0.3 1.6 1 0 0 1 1 1 1 Ubiquitin-activating enzyme E1 FCCH domain E1_4HB PF16191.5 OQS07784.1 - 1.4e-17 63.6 0.0 2.6e-17 62.8 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-activating enzyme E1 four-helix bundle Shikimate_DH PF01488.20 OQS07784.1 - 0.11 12.5 0.5 5.8 7.0 0.0 3.0 2 1 1 3 3 3 0 Shikimate / quinate 5-dehydrogenase KOG2701 PF09762.9 OQS07785.1 - 5.4e-19 69.1 0.2 8.5e-19 68.5 0.2 1.2 1 0 0 1 1 1 1 Coiled-coil domain-containing protein (DUF2037) Myosin_head PF00063.21 OQS07786.1 - 1.9e-56 191.7 0.0 2.5e-56 191.3 0.0 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) CbiJ PF02571.14 OQS07786.1 - 0.11 12.0 0.1 1.6 8.2 0.0 2.1 2 0 0 2 2 2 0 Precorrin-6x reductase CbiJ/CobK Cob_adeno_trans PF01923.18 OQS07787.1 - 3.4e-55 186.7 0.0 4.1e-55 186.4 0.0 1.1 1 0 0 1 1 1 1 Cobalamin adenosyltransferase MMR_HSR1 PF01926.23 OQS07788.1 - 1.6e-52 176.4 0.2 1.8e-25 89.2 0.0 2.2 2 0 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.18 OQS07788.1 - 4.1e-30 104.4 0.1 1.4e-17 63.7 0.2 2.2 2 0 0 2 2 2 2 Ferrous iron transport protein B GTP_EFTU PF00009.27 OQS07788.1 - 4.2e-15 55.8 0.2 5.7e-08 32.5 0.4 5.0 3 2 0 3 3 3 2 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 OQS07788.1 - 4.7e-14 52.8 0.8 0.003 17.6 0.0 4.3 3 1 1 4 4 4 4 Dynamin family Ras PF00071.22 OQS07788.1 - 1.9e-13 50.3 0.0 5e-08 32.7 0.0 3.2 2 2 0 2 2 2 2 Ras family AIG1 PF04548.16 OQS07788.1 - 1.7e-10 40.6 0.1 2e-05 24.0 0.1 2.3 2 0 0 2 2 2 2 AIG1 family Roc PF08477.13 OQS07788.1 - 4e-10 39.9 0.2 0.0015 18.7 0.0 3.9 2 2 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OQS07788.1 - 1.1e-09 38.0 0.2 2.3e-05 23.9 0.1 3.2 2 2 0 2 2 2 2 ADP-ribosylation factor family RsgA_GTPase PF03193.16 OQS07788.1 - 4.4e-09 36.5 0.1 0.0099 15.8 0.0 3.6 2 1 1 3 3 3 2 RsgA GTPase SRPRB PF09439.10 OQS07788.1 - 1.6e-07 31.0 0.2 0.004 16.6 0.0 2.5 3 0 0 3 3 2 2 Signal recognition particle receptor beta subunit NB-ARC PF00931.22 OQS07788.1 - 2e-07 30.5 0.1 0.00011 21.5 0.2 2.2 2 0 0 2 2 2 2 NB-ARC domain ABC_tran PF00005.27 OQS07788.1 - 9.9e-07 29.4 0.0 0.052 14.1 0.0 2.4 2 0 0 2 2 2 2 ABC transporter AAA_22 PF13401.6 OQS07788.1 - 1.8e-05 25.0 0.3 0.33 11.2 0.1 3.0 2 2 0 2 2 2 2 AAA domain TniB PF05621.11 OQS07788.1 - 2.8e-05 23.6 0.0 0.11 11.9 0.0 2.4 2 0 0 2 2 2 2 Bacterial TniB protein AAA_29 PF13555.6 OQS07788.1 - 0.00017 21.2 0.0 0.35 10.6 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_18 PF13238.6 OQS07788.1 - 0.0004 20.9 0.1 0.72 10.4 0.0 2.6 2 1 0 2 2 2 2 AAA domain NTPase_1 PF03266.15 OQS07788.1 - 0.0016 18.4 0.6 0.55 10.1 0.0 2.9 3 0 0 3 3 3 1 NTPase G-alpha PF00503.20 OQS07788.1 - 0.0017 17.6 0.0 0.81 8.8 0.0 2.4 2 1 0 2 2 2 2 G-protein alpha subunit AAA_24 PF13479.6 OQS07788.1 - 0.0017 18.1 0.0 0.6 9.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 OQS07788.1 - 0.0024 18.2 0.0 2.4 8.6 0.0 2.6 2 1 0 2 2 2 1 RNA helicase MeaB PF03308.16 OQS07788.1 - 0.004 16.2 0.1 2.6 6.9 0.0 3.4 3 1 1 4 4 4 1 Methylmalonyl Co-A mutase-associated GTPase MeaB Septin PF00735.18 OQS07788.1 - 0.0089 15.3 0.0 3.1 7.0 0.0 2.7 2 1 0 2 2 2 1 Septin MobB PF03205.14 OQS07788.1 - 0.014 15.3 0.0 5.9 6.8 0.0 2.9 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B FtsK_SpoIIIE PF01580.18 OQS07788.1 - 0.023 14.1 0.1 13 5.1 0.0 3.2 2 1 1 3 3 3 0 FtsK/SpoIIIE family ATPase_2 PF01637.18 OQS07788.1 - 0.023 14.6 0.0 2.1 8.2 0.0 2.4 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea AAA_25 PF13481.6 OQS07788.1 - 0.025 14.2 0.2 7.4 6.1 0.0 3.1 3 1 1 4 4 3 0 AAA domain AAA_14 PF13173.6 OQS07788.1 - 0.037 14.0 0.1 5.1 7.2 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 OQS07788.1 - 0.057 13.8 0.2 15 5.9 0.1 2.6 2 2 0 2 2 2 0 AAA ATPase domain AAA_28 PF13521.6 OQS07788.1 - 0.072 13.3 0.0 16 5.7 0.0 2.5 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 OQS07788.1 - 0.13 12.2 0.0 12 5.7 0.0 3.0 3 0 0 3 3 3 0 NACHT domain PduV-EutP PF10662.9 OQS07788.1 - 0.17 11.7 0.0 5.8 6.6 0.0 3.1 4 1 0 4 4 4 0 Ethanolamine utilisation - propanediol utilisation CTP_transf_like PF01467.26 OQS07789.1 - 2.2e-13 50.6 0.1 3.7e-12 46.6 0.1 2.6 2 0 0 2 2 2 1 Cytidylyltransferase-like fn3 PF00041.21 OQS07790.1 - 6.7e-47 157.8 30.6 8.1e-12 45.3 0.3 8.4 9 0 0 9 9 9 6 Fibronectin type III domain LRR_6 PF13516.6 OQS07790.1 - 4.5e-14 51.2 31.1 0.0042 17.0 0.1 9.7 9 0 0 9 9 9 5 Leucine Rich repeat TRP PF06011.12 OQS07790.1 - 5.2e-06 25.5 6.3 5.2e-06 25.5 6.3 2.2 2 0 0 2 2 2 1 Transient receptor potential (TRP) ion channel Pur_ac_phosph_N PF16656.5 OQS07790.1 - 0.00013 22.5 15.4 0.26 11.9 0.0 6.7 4 2 1 5 5 5 2 Purple acid Phosphatase, N-terminal domain CUB PF00431.20 OQS07790.1 - 0.00065 20.0 0.0 0.0051 17.1 0.0 2.4 2 0 0 2 2 2 1 CUB domain EGF_2 PF07974.13 OQS07790.1 - 0.0019 18.5 12.6 0.0068 16.7 12.6 2.1 1 0 0 1 1 1 1 EGF-like domain DUF2369 PF10179.9 OQS07790.1 - 0.029 14.8 1.7 4.5 7.7 0.3 4.7 5 0 0 5 5 5 0 Uncharacterised conserved protein (DUF2369) Chlam_PMP PF02415.17 OQS07790.1 - 0.064 13.8 0.1 0.064 13.8 0.1 25.4 31 1 0 31 31 26 0 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat EGF PF00008.27 OQS07790.1 - 0.3 11.4 6.6 1.4 9.3 6.6 2.3 1 0 0 1 1 1 0 EGF-like domain LRR_1 PF00560.33 OQS07790.1 - 0.33 11.7 16.9 38 5.4 0.6 8.1 9 0 0 9 9 9 0 Leucine Rich Repeat hEGF PF12661.7 OQS07790.1 - 3.1 8.6 7.4 22 5.8 7.4 2.7 1 0 0 1 1 1 0 Human growth factor-like EGF RRM_1 PF00076.22 OQS07791.1 - 6e-08 32.4 0.0 8.4e-08 31.9 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 OQS07791.1 - 0.0022 17.6 0.0 0.0022 17.6 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ERbeta_N PF12497.8 OQS07791.1 - 0.032 14.0 0.0 0.04 13.7 0.0 1.2 1 0 0 1 1 1 0 Estrogen receptor beta Limkain-b1 PF11608.8 OQS07791.1 - 0.039 14.0 0.1 0.048 13.7 0.1 1.2 1 0 0 1 1 1 0 Limkain b1 CLP1_P PF16575.5 OQS07792.1 - 3.4e-29 102.0 0.0 5.3e-29 101.4 0.0 1.3 1 0 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop DUF1775 PF07987.11 OQS07792.1 - 9e-27 94.2 0.0 1.8e-26 93.2 0.0 1.5 1 0 0 1 1 1 1 Domain of unkown function (DUF1775) Clp1 PF06807.14 OQS07792.1 - 8.8e-08 32.6 0.0 2.1e-07 31.3 0.0 1.7 2 0 0 2 2 2 1 Pre-mRNA cleavage complex II protein Clp1 Glyco_hydro_16 PF00722.21 OQS07793.1 - 5.1e-23 81.4 2.9 6.7e-13 48.5 1.2 2.6 2 1 0 2 2 2 2 Glycosyl hydrolases family 16 SAM_1 PF00536.30 OQS07794.1 - 6.5e-05 23.3 0.2 0.00021 21.7 0.0 1.9 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 OQS07794.1 - 0.00073 19.6 0.1 0.0035 17.4 0.0 2.1 1 1 1 2 2 2 1 SAM domain (Sterile alpha motif) HhH-GPD PF00730.25 OQS07794.1 - 0.089 13.3 0.0 0.22 12.0 0.0 1.6 1 0 0 1 1 1 0 HhH-GPD superfamily base excision DNA repair protein FGGY_C PF02782.16 OQS07794.1 - 0.16 11.6 0.0 0.23 11.1 0.0 1.2 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain Citrate_synt PF00285.21 OQS07795.1 - 1.5e-14 53.9 0.0 1.3e-13 50.8 0.0 1.9 1 1 0 1 1 1 1 Citrate synthase, C-terminal domain Citrate_synt PF00285.21 OQS07796.1 - 6e-06 25.6 0.3 0.0019 17.3 0.3 2.1 1 1 1 2 2 2 2 Citrate synthase, C-terminal domain Ligase_CoA PF00549.19 OQS07796.1 - 0.0013 18.5 0.0 0.0018 18.1 0.0 1.2 1 0 0 1 1 1 1 CoA-ligase IF4E PF01652.18 OQS07797.1 - 3.4e-59 199.2 6.9 8.6e-32 110.1 1.4 2.1 2 0 0 2 2 2 2 Eukaryotic initiation factor 4E Dyp_perox PF04261.12 OQS07797.1 - 0.14 11.2 0.0 0.19 10.7 0.0 1.1 1 0 0 1 1 1 0 Dyp-type peroxidase family RRM_1 PF00076.22 OQS07802.1 - 2.1e-28 97.9 0.1 4.6e-16 58.4 0.0 3.9 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 OQS07802.1 - 2.9e-05 23.8 0.0 0.034 14.0 0.0 3.5 3 0 0 3 3 3 1 Occluded RNA-recognition motif RRM_7 PF16367.5 OQS07802.1 - 0.00014 21.9 0.0 0.0019 18.3 0.0 2.4 2 0 0 2 2 2 1 RNA recognition motif fn3 PF00041.21 OQS07803.1 - 5e-38 129.3 35.2 4.9e-11 42.8 0.2 9.9 10 1 0 10 10 10 9 Fibronectin type III domain DUF2369 PF10179.9 OQS07803.1 - 2.5e-08 34.2 9.2 0.076 13.4 0.0 6.4 7 0 0 7 7 7 4 Uncharacterised conserved protein (DUF2369) Pur_ac_phosph_N PF16656.5 OQS07803.1 - 0.00075 20.0 33.5 0.54 10.9 0.1 9.1 9 2 0 9 9 9 4 Purple acid Phosphatase, N-terminal domain NAR2 PF16974.5 OQS07803.1 - 0.79 9.1 8.8 13 5.1 0.0 5.5 6 1 1 7 7 7 0 High-affinity nitrate transporter accessory Prefoldin_2 PF01920.20 OQS07804.1 - 1e-16 60.8 4.5 1e-16 60.8 4.5 1.9 2 0 0 2 2 2 1 Prefoldin subunit TPR_1 PF00515.28 OQS07804.1 - 8e-14 50.8 6.9 2e-06 27.4 0.2 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 OQS07804.1 - 5.5e-11 41.7 5.8 0.0016 18.4 0.1 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 OQS07804.1 - 5e-08 32.5 6.3 1e-06 28.3 1.4 3.3 1 1 1 3 3 3 1 TPR repeat TPR_8 PF13181.6 OQS07804.1 - 7.7e-07 28.8 9.6 0.052 13.8 0.0 4.2 5 0 0 5 5 3 3 Tetratricopeptide repeat TPR_17 PF13431.6 OQS07804.1 - 0.00019 21.6 3.7 0.092 13.2 0.2 3.0 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 OQS07804.1 - 0.00036 20.8 5.4 0.0012 19.1 0.2 3.0 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 OQS07804.1 - 0.00044 20.8 2.4 0.73 10.8 0.0 4.0 2 1 2 4 4 3 1 Tetratricopeptide repeat DHR10 PF18595.1 OQS07804.1 - 0.0011 19.0 10.9 0.58 10.2 0.3 3.3 3 0 0 3 3 3 2 Designed helical repeat protein 10 domain TPR_6 PF13174.6 OQS07804.1 - 0.0023 18.5 2.7 1.8 9.4 0.8 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 OQS07804.1 - 0.0023 18.5 7.0 0.64 10.7 0.4 3.3 3 1 1 4 4 3 2 Tetratricopeptide repeat Lectin_N PF03954.14 OQS07804.1 - 0.0023 17.7 2.2 0.048 13.4 0.4 2.2 2 0 0 2 2 2 1 Hepatic lectin, N-terminal domain TPR_7 PF13176.6 OQS07804.1 - 0.005 16.8 0.4 2.5 8.4 0.1 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_10 PF13374.6 OQS07804.1 - 0.0072 16.2 9.6 0.26 11.2 0.2 3.8 4 0 0 4 4 3 1 Tetratricopeptide repeat Baculo_PEP_C PF04513.12 OQS07804.1 - 0.0074 16.3 0.2 0.94 9.5 0.1 2.2 2 0 0 2 2 2 1 Baculovirus polyhedron envelope protein, PEP, C terminus DUF5320 PF17253.2 OQS07804.1 - 0.0083 17.2 3.9 1.2 10.2 0.2 2.5 2 0 0 2 2 2 1 Family of unknown function (DUF5320) DUF3450 PF11932.8 OQS07804.1 - 0.0095 15.3 9.4 0.16 11.3 1.2 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF3450) TPR_19 PF14559.6 OQS07804.1 - 0.011 16.3 10.5 0.056 14.0 0.3 3.5 3 1 1 4 4 2 0 Tetratricopeptide repeat DUF4140 PF13600.6 OQS07804.1 - 0.012 16.0 5.1 1 9.9 0.1 2.6 2 1 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) Prefoldin PF02996.17 OQS07804.1 - 0.012 15.5 7.2 0.9 9.5 7.3 2.6 1 1 0 1 1 1 0 Prefoldin subunit ADIP PF11559.8 OQS07804.1 - 0.019 15.1 8.8 0.15 12.1 2.6 2.5 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding Jnk-SapK_ap_N PF09744.9 OQS07804.1 - 0.023 14.9 14.2 0.057 13.6 1.8 2.9 2 1 1 3 3 3 0 JNK_SAPK-associated protein-1 Fib_alpha PF08702.10 OQS07804.1 - 0.033 14.4 0.9 0.033 14.4 0.9 1.9 2 0 0 2 2 1 0 Fibrinogen alpha/beta chain family HMMR_N PF15905.5 OQS07804.1 - 0.037 13.5 8.1 1.5 8.2 1.2 2.6 2 1 0 2 2 2 0 Hyaluronan mediated motility receptor N-terminal DASH_Dad2 PF08654.10 OQS07804.1 - 0.038 14.4 2.1 4.9 7.6 0.0 2.9 3 0 0 3 3 2 0 DASH complex subunit Dad2 Fungal_TACC PF12709.7 OQS07804.1 - 0.042 14.3 4.3 0.12 12.8 0.5 2.5 2 0 0 2 2 2 0 Fungal Transforming acidic coiled-coil (TACC) proteins COG2 PF06148.11 OQS07804.1 - 0.042 13.9 1.0 0.92 9.6 0.0 2.8 3 0 0 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 SKA2 PF16740.5 OQS07804.1 - 0.054 13.3 7.1 0.23 11.3 0.8 2.7 2 1 1 3 3 2 0 Spindle and kinetochore-associated protein 2 CLZ PF16526.5 OQS07804.1 - 0.056 13.8 4.2 1.7 9.0 0.2 2.8 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels RasGAP_C PF03836.15 OQS07804.1 - 0.056 13.6 3.4 0.3 11.2 0.6 2.4 2 0 0 2 2 2 0 RasGAP C-terminus BLOC1_2 PF10046.9 OQS07804.1 - 0.06 13.7 2.6 5.6 7.3 0.5 2.6 2 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF812 PF05667.11 OQS07804.1 - 0.07 12.0 9.3 0.077 11.9 9.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) FapA PF03961.13 OQS07804.1 - 0.079 11.6 7.8 0.027 13.1 1.5 2.0 1 1 1 2 2 2 0 Flagellar Assembly Protein A PspB PF06667.12 OQS07804.1 - 0.093 12.8 2.1 6.7 6.8 0.2 2.7 2 0 0 2 2 2 0 Phage shock protein B XhlA PF10779.9 OQS07804.1 - 0.11 12.7 4.3 0.17 12.1 1.2 2.4 2 0 0 2 2 2 0 Haemolysin XhlA Spc24 PF08286.11 OQS07804.1 - 0.11 12.7 4.7 3.4 7.9 0.1 2.6 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 Sec34 PF04136.15 OQS07804.1 - 0.12 12.3 3.7 3.2 7.6 1.2 2.3 2 0 0 2 2 2 0 Sec34-like family WXG100 PF06013.12 OQS07804.1 - 0.12 12.6 5.0 2 8.7 0.0 3.2 3 0 0 3 3 3 0 Proteins of 100 residues with WXG NPV_P10 PF05531.12 OQS07804.1 - 0.12 12.9 0.7 22 5.6 0.2 2.3 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein HSBP1 PF06825.12 OQS07804.1 - 0.13 12.1 0.3 4 7.4 0.0 2.6 2 0 0 2 2 2 0 Heat shock factor binding protein 1 KASH_CCD PF14662.6 OQS07804.1 - 0.21 11.4 6.6 0.64 9.8 1.5 2.4 2 0 0 2 2 2 0 Coiled-coil region of CCDC155 or KASH GAS PF13851.6 OQS07804.1 - 0.24 10.7 13.3 0.073 12.4 0.8 2.7 3 0 0 3 3 3 0 Growth-arrest specific micro-tubule binding CCDC-167 PF15188.6 OQS07804.1 - 0.25 11.7 2.8 1 9.8 0.1 2.5 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 Nsp1_C PF05064.13 OQS07804.1 - 0.44 10.4 7.8 0.42 10.4 0.6 2.6 3 0 0 3 3 2 0 Nsp1-like C-terminal region CENP-F_leu_zip PF10473.9 OQS07804.1 - 0.5 10.4 13.1 0.2 11.7 0.6 2.7 3 0 0 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Spc7 PF08317.11 OQS07804.1 - 0.76 8.6 10.7 1 8.2 8.2 2.0 1 1 1 2 2 2 0 Spc7 kinetochore protein DUF3847 PF12958.7 OQS07804.1 - 0.77 9.9 6.2 8.5 6.6 0.4 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3847) YabA PF06156.13 OQS07804.1 - 0.87 10.3 9.0 1.2 9.8 0.4 2.7 2 1 0 3 3 2 0 Initiation control protein YabA DUF724 PF05266.14 OQS07804.1 - 0.9 9.3 7.3 3.3 7.5 0.5 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF724) UPF0242 PF06785.11 OQS07804.1 - 0.91 9.6 8.2 1.1 9.3 7.1 1.8 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Ax_dynein_light PF10211.9 OQS07804.1 - 1.1 9.2 9.7 1.1 9.1 1.0 2.5 2 1 0 2 2 2 0 Axonemal dynein light chain Syntaxin_2 PF14523.6 OQS07804.1 - 1.2 9.6 7.2 6.2 7.3 0.9 3.1 3 0 0 3 3 3 0 Syntaxin-like protein DivIC PF04977.15 OQS07804.1 - 1.3 8.8 7.9 2.4 8.0 1.4 2.7 2 0 0 2 2 2 0 Septum formation initiator TMF_DNA_bd PF12329.8 OQS07804.1 - 1.4 9.0 8.4 4.9 7.2 2.2 2.7 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding ATG16 PF08614.11 OQS07804.1 - 1.4 9.1 12.2 5.5 7.2 1.5 2.4 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) TMF_TATA_bd PF12325.8 OQS07804.1 - 1.7 8.9 11.4 0.77 10.0 1.6 2.7 2 1 1 3 3 2 0 TATA element modulatory factor 1 TATA binding ABC_tran_CTD PF16326.5 OQS07804.1 - 1.9 8.8 11.7 0.63 10.3 0.7 3.4 3 1 0 3 3 3 0 ABC transporter C-terminal domain Tropomyosin_1 PF12718.7 OQS07804.1 - 2 8.6 12.4 3.3 7.9 1.6 2.8 2 1 0 2 2 2 0 Tropomyosin like Leu_zip PF15294.6 OQS07804.1 - 2.5 7.5 10.0 35 3.8 9.4 2.2 1 1 0 1 1 1 0 Leucine zipper bZIP_2 PF07716.15 OQS07804.1 - 2.9 8.0 10.4 4.9 7.3 0.7 3.5 3 0 0 3 3 3 0 Basic region leucine zipper APG6_N PF17675.1 OQS07804.1 - 4.4 7.8 17.3 15 6.1 3.8 2.8 1 1 1 2 2 2 0 Apg6 coiled-coil region TPR_MLP1_2 PF07926.12 OQS07804.1 - 4.8 7.2 18.3 0.22 11.6 2.0 2.9 3 1 0 3 3 2 0 TPR/MLP1/MLP2-like protein GIT_CC PF16559.5 OQS07804.1 - 5.4 6.9 7.5 12 5.9 0.3 3.0 3 0 0 3 3 3 0 GIT coiled-coil Rho guanine nucleotide exchange factor bZIP_Maf PF03131.17 OQS07804.1 - 6.9 7.3 11.3 6.7 7.3 0.9 3.3 3 0 0 3 3 3 0 bZIP Maf transcription factor BRE1 PF08647.11 OQS07804.1 - 7.4 6.7 14.9 3.7 7.7 1.1 3.1 3 0 0 3 3 3 0 BRE1 E3 ubiquitin ligase SlyX PF04102.12 OQS07804.1 - 8.5 7.1 9.4 7.5 7.3 0.6 3.0 3 0 0 3 3 3 0 SlyX AAA_13 PF13166.6 OQS07804.1 - 8.8 4.8 11.9 2.2 6.8 1.5 2.3 1 1 2 3 3 3 0 AAA domain DUF5082 PF16888.5 OQS07804.1 - 9.1 6.6 9.6 3.3 8.0 0.8 2.9 4 0 0 4 4 2 0 Domain of unknown function (DUF5082) DivIC PF04977.15 OQS07805.1 - 0.0074 16.0 0.9 0.012 15.4 0.9 1.4 1 0 0 1 1 1 1 Septum formation initiator FlaC_arch PF05377.11 OQS07805.1 - 0.027 14.9 1.5 0.11 12.9 0.3 2.1 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) Erf4 PF10256.9 OQS07805.1 - 0.034 14.2 0.0 0.039 14.1 0.0 1.2 1 0 0 1 1 1 0 Golgin subfamily A member 7/ERF4 family ZapB PF06005.12 OQS07805.1 - 0.11 12.9 10.6 0.21 12.0 10.6 1.4 1 0 0 1 1 1 0 Cell division protein ZapB zf-C2H2 PF00096.26 OQS07808.1 - 1.3e-08 34.8 9.8 0.00074 19.8 3.6 2.5 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 OQS07808.1 - 1.5e-08 34.6 10.1 0.00049 20.4 0.3 3.3 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 OQS07808.1 - 0.00054 20.6 8.1 0.043 14.7 2.4 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_8 PF15909.5 OQS07808.1 - 0.037 14.3 3.6 2.5 8.5 0.4 2.5 1 1 1 2 2 2 0 C2H2-type zinc ribbon zf-met PF12874.7 OQS07808.1 - 0.13 12.6 4.7 0.8 10.2 0.2 2.7 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_aberr PF17017.5 OQS07808.1 - 0.66 10.1 1.9 14 5.7 0.0 2.0 1 1 1 2 2 2 0 Aberrant zinc-finger zf-H2C2_5 PF13909.6 OQS07808.1 - 1.9 8.3 12.4 0.089 12.6 3.5 2.9 3 1 0 3 3 3 0 C2H2-type zinc-finger domain TTL PF03133.15 OQS07809.1 - 4e-27 95.1 0.1 1.8e-26 93.0 0.1 2.0 2 1 0 2 2 2 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 OQS07809.1 - 7.9e-05 22.0 0.0 0.00012 21.4 0.0 1.2 1 0 0 1 1 1 1 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 OQS07809.1 - 0.00016 21.0 0.0 0.00064 19.0 0.0 1.8 2 0 0 2 2 2 1 Sugar-transfer associated ATP-grasp TTL PF03133.15 OQS07810.1 - 9.9e-45 152.9 0.2 1.3e-44 152.6 0.2 1.1 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family Methyltransf_34 PF11312.8 OQS07810.1 - 0.085 12.1 0.0 0.12 11.6 0.0 1.2 1 0 0 1 1 1 0 Putative SAM-dependent methyltransferase DUF2052 PF09747.9 OQS07811.1 - 1.1e-25 91.0 16.4 3e-25 89.5 16.4 1.6 1 1 0 1 1 1 1 Coiled-coil domain containing protein (DUF2052) PBP1_TM PF14812.6 OQS07811.1 - 0.33 11.3 11.1 0.11 12.9 6.7 2.2 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal PseudoU_synth_2 PF00849.22 OQS07812.1 - 6.7e-15 55.5 0.4 5.7e-14 52.5 0.4 2.3 1 1 0 1 1 1 1 RNA pseudouridylate synthase S4 PF01479.25 OQS07812.1 - 1.3e-09 37.6 1.3 2.2e-09 36.9 0.1 2.1 2 0 0 2 2 2 1 S4 domain S4_2 PF13275.6 OQS07812.1 - 0.0015 18.3 0.0 0.011 15.5 0.0 2.2 2 0 0 2 2 2 1 S4 domain Dus PF01207.17 OQS07813.1 - 1.3e-61 208.5 0.0 5.3e-41 140.7 0.0 2.0 1 1 1 2 2 2 2 Dihydrouridine synthase (Dus) zf_C2H2_13 PF18508.1 OQS07813.1 - 0.022 14.3 0.0 0.072 12.7 0.0 1.8 2 0 0 2 2 2 0 Zinc finger domain Glyco_hydro_18 PF00704.28 OQS07813.1 - 0.026 14.2 0.0 0.049 13.3 0.0 1.4 1 0 0 1 1 1 0 Glycosyl hydrolases family 18 Helicase_C PF00271.31 OQS07815.1 - 1.4e-08 35.1 0.0 3e-08 34.0 0.0 1.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ABC_tran PF00005.27 OQS07816.1 - 1.5e-44 151.9 0.0 7.7e-27 94.5 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 OQS07816.1 - 1.7e-16 60.7 6.9 1.7e-16 60.7 6.9 1.8 2 1 0 2 2 2 1 ABC transporter transmembrane region SMC_N PF02463.19 OQS07816.1 - 1.9e-06 27.5 2.6 0.034 13.6 0.0 4.2 4 0 0 4 4 4 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 OQS07816.1 - 2.3e-06 27.3 2.5 0.049 13.4 0.1 2.8 3 0 0 3 3 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 OQS07816.1 - 3.7e-06 27.0 0.0 0.037 13.9 0.0 2.6 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 OQS07816.1 - 5.1e-06 26.5 0.1 0.049 13.7 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_22 PF13401.6 OQS07816.1 - 5.7e-06 26.6 0.3 0.12 12.7 0.1 2.7 2 1 0 2 2 2 2 AAA domain Dynamin_N PF00350.23 OQS07816.1 - 1.3e-05 25.4 1.5 0.0042 17.2 0.1 2.6 2 0 0 2 2 2 1 Dynamin family AAA_18 PF13238.6 OQS07816.1 - 5.2e-05 23.8 0.5 0.32 11.6 0.0 3.2 3 1 0 3 3 2 2 AAA domain AAA_21 PF13304.6 OQS07816.1 - 9.5e-05 22.3 0.2 0.37 10.6 0.0 3.0 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system T2SSE PF00437.20 OQS07816.1 - 0.00014 21.0 0.0 0.21 10.6 0.0 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_23 PF13476.6 OQS07816.1 - 0.00015 22.4 0.1 0.66 10.5 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 OQS07816.1 - 0.00018 21.9 0.1 0.036 14.5 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain NACHT PF05729.12 OQS07816.1 - 0.00064 19.7 0.2 1.4 8.8 0.0 2.5 2 0 0 2 2 2 2 NACHT domain AAA_33 PF13671.6 OQS07816.1 - 0.00065 19.9 0.7 0.84 9.8 0.2 2.7 2 1 0 2 2 2 2 AAA domain AAA_7 PF12775.7 OQS07816.1 - 0.0011 18.6 0.0 0.99 8.9 0.0 2.5 2 0 0 2 2 2 2 P-loop containing dynein motor region cobW PF02492.19 OQS07816.1 - 0.0012 18.4 0.5 0.42 10.2 0.1 2.4 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain FtsK_SpoIIIE PF01580.18 OQS07816.1 - 0.0034 16.8 0.3 0.81 9.0 0.1 2.4 2 0 0 2 2 2 1 FtsK/SpoIIIE family ATPase_2 PF01637.18 OQS07816.1 - 0.0044 17.0 0.0 0.56 10.1 0.0 2.4 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea AAA PF00004.29 OQS07816.1 - 0.0075 16.7 0.2 0.2 12.1 0.0 2.8 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 OQS07816.1 - 0.014 15.0 0.1 6.2 6.3 0.1 2.3 2 0 0 2 2 2 0 AAA domain ATP_bind_1 PF03029.17 OQS07816.1 - 0.016 15.0 0.5 5.6 6.7 0.0 2.7 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein dNK PF01712.19 OQS07816.1 - 0.023 14.6 0.1 0.56 10.0 0.0 2.3 2 0 0 2 2 2 0 Deoxynucleoside kinase TsaE PF02367.17 OQS07816.1 - 0.024 14.6 0.1 1.7 8.6 0.0 2.4 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE NB-ARC PF00931.22 OQS07816.1 - 0.026 13.7 0.4 2.6 7.1 0.2 2.4 2 0 0 2 2 2 0 NB-ARC domain RNA_helicase PF00910.22 OQS07816.1 - 0.028 14.8 0.2 9.8 6.6 0.0 2.7 2 0 0 2 2 2 0 RNA helicase DUF87 PF01935.17 OQS07816.1 - 0.044 13.9 3.9 0.47 10.5 0.3 2.6 3 0 0 3 3 2 0 Helicase HerA, central domain IstB_IS21 PF01695.17 OQS07816.1 - 0.088 12.5 0.3 22 4.7 0.0 3.2 3 0 0 3 3 3 0 IstB-like ATP binding protein DUF815 PF05673.13 OQS07816.1 - 0.093 11.9 0.0 0.8 8.8 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF815) KAP_NTPase PF07693.14 OQS07816.1 - 0.093 11.9 0.0 0.55 9.4 0.0 2.1 2 0 0 2 2 2 0 KAP family P-loop domain Roc PF08477.13 OQS07816.1 - 0.11 12.8 0.3 11 6.3 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase BPTA PF17044.5 OQS07816.1 - 0.14 12.0 0.0 0.29 11.0 0.0 1.4 1 0 0 1 1 1 0 Borrelial persistence in ticks protein A AAA_24 PF13479.6 OQS07816.1 - 0.16 11.7 0.1 8.9 6.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_15 PF13175.6 OQS07816.1 - 0.17 11.5 0.3 5.2 6.7 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain Zeta_toxin PF06414.12 OQS07816.1 - 0.2 10.9 0.1 14 4.9 0.0 2.2 2 0 0 2 2 2 0 Zeta toxin AAA_30 PF13604.6 OQS07816.1 - 0.25 11.0 1.3 20 4.8 0.0 2.6 3 0 0 3 3 3 0 AAA domain PLAC8 PF04749.17 OQS07817.1 - 1.7e-19 70.6 11.5 2.3e-19 70.2 11.5 1.2 1 0 0 1 1 1 1 PLAC8 family LapA_dom PF06305.11 OQS07817.1 - 0.0061 16.3 0.5 0.011 15.6 0.5 1.3 1 0 0 1 1 1 1 Lipopolysaccharide assembly protein A domain LRR_8 PF13855.6 OQS07818.1 - 2.8e-13 49.4 4.4 8.3e-05 22.3 0.1 4.4 3 1 1 5 5 5 3 Leucine rich repeat LRR_4 PF12799.7 OQS07818.1 - 1.4e-07 31.7 14.4 0.00076 19.8 0.0 5.2 6 0 0 6 6 6 2 Leucine Rich repeats (2 copies) Notch PF00066.17 OQS07818.1 - 0.024 15.1 2.9 0.024 15.1 2.9 2.4 2 1 0 2 2 2 0 LNR domain LRR_6 PF13516.6 OQS07818.1 - 0.048 13.7 6.4 65 4.0 0.1 5.9 6 0 0 6 6 6 0 Leucine Rich repeat LRR_1 PF00560.33 OQS07818.1 - 0.95 10.3 11.5 18 6.4 0.0 6.4 7 1 0 7 7 7 0 Leucine Rich Repeat Imm1 PF14430.6 OQS07819.1 - 0.086 13.5 0.0 0.13 12.9 0.0 1.2 1 0 0 1 1 1 0 Immunity protein Imm1 ALS_ss_C PF10369.9 OQS07820.1 - 1.6e-23 82.7 0.0 5.9e-23 80.9 0.0 1.9 2 0 0 2 2 2 1 Small subunit of acetolactate synthase ACT PF01842.25 OQS07820.1 - 5e-08 32.6 0.1 1.1e-07 31.5 0.1 1.6 1 0 0 1 1 1 1 ACT domain ACT_5 PF13710.6 OQS07820.1 - 1.9e-05 24.4 2.3 3.6e-05 23.5 0.0 2.5 2 1 1 3 3 3 1 ACT domain LytTR PF04397.15 OQS07820.1 - 0.013 15.7 0.0 0.19 12.0 0.0 2.3 2 0 0 2 2 2 0 LytTr DNA-binding domain Pkinase PF00069.25 OQS07822.1 - 1.9e-51 174.9 0.0 3.6e-51 174.1 0.0 1.4 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQS07822.1 - 3.5e-50 170.7 0.0 6.5e-50 169.8 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Ank_4 PF13637.6 OQS07822.1 - 9.2e-11 42.1 0.1 4.8e-06 27.0 0.1 2.6 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 OQS07822.1 - 8.3e-08 32.7 0.3 1.9e-07 31.6 0.3 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OQS07822.1 - 4.4e-07 30.0 0.6 4.9e-06 26.7 0.1 2.9 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQS07822.1 - 2.5e-06 27.4 0.6 0.0042 17.5 0.1 3.9 3 1 0 3 3 3 1 Ankyrin repeat Haspin_kinase PF12330.8 OQS07822.1 - 3.3e-06 26.3 0.4 8.9e-06 24.9 0.4 1.6 1 1 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 OQS07822.1 - 0.0048 16.3 0.0 0.0088 15.4 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Ank PF00023.30 OQS07822.1 - 0.0049 17.3 1.4 0.57 10.7 0.2 3.4 3 0 0 3 3 3 1 Ankyrin repeat Kdo PF06293.14 OQS07822.1 - 0.016 14.5 0.0 0.028 13.8 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Ribosomal_L32p PF01783.23 OQS07823.1 - 1e-10 41.7 5.4 1.3e-10 41.4 5.4 1.1 1 0 0 1 1 1 1 Ribosomal L32p protein family Sds3 PF08598.11 OQS07824.1 - 1.9e-05 24.8 9.3 1.9e-05 24.8 9.3 2.4 2 1 0 2 2 2 1 Sds3-like ALMT PF11744.8 OQS07824.1 - 0.08 11.8 4.2 1.2 7.9 2.3 2.2 2 0 0 2 2 2 0 Aluminium activated malate transporter PIN_8 PF18476.1 OQS07824.1 - 3.5 7.4 11.6 1 9.2 1.6 2.2 1 1 1 2 2 2 0 PIN like domain DNA_pol_B_exo1 PF03104.19 OQS07825.1 - 5.1e-69 233.0 0.3 6.9e-69 232.5 0.3 1.2 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_B_exo2 PF10108.9 OQS07825.1 - 1.8e-09 37.6 0.4 1e-08 35.1 0.4 2.1 1 1 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB RNase_H_2 PF13482.6 OQS07825.1 - 7.4e-05 22.8 0.1 0.00087 19.3 0.0 2.7 2 1 0 2 2 2 1 RNase_H superfamily HLH PF00010.26 OQS07826.1 - 4.1e-05 23.5 3.3 0.0014 18.5 0.3 2.4 2 0 0 2 2 2 2 Helix-loop-helix DNA-binding domain F-box-like PF12937.7 OQS07826.1 - 0.00019 21.3 0.0 0.00044 20.1 0.0 1.7 1 0 0 1 1 1 1 F-box-like Cep57_CLD_2 PF14197.6 OQS07826.1 - 0.06 13.4 0.2 0.11 12.6 0.2 1.4 1 0 0 1 1 1 0 Centrosome localisation domain of PPC89 Mito_fiss_reg PF05308.11 OQS07826.1 - 0.3 11.1 7.7 0.21 11.7 3.7 1.9 1 1 1 2 2 2 0 Mitochondrial fission regulator SlyX PF04102.12 OQS07827.1 - 0.0059 17.2 1.8 0.0059 17.2 1.8 5.7 5 1 1 6 6 6 1 SlyX DUF948 PF06103.11 OQS07827.1 - 6.7 7.0 14.4 1.7 9.0 0.8 4.5 4 1 0 4 4 4 0 Bacterial protein of unknown function (DUF948) Metallophos PF00149.28 OQS07828.1 - 4.1e-12 47.0 0.0 7.6e-12 46.2 0.0 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 OQS07828.1 - 0.0027 17.9 0.0 0.022 14.9 0.0 2.2 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Ion_trans PF00520.31 OQS07829.1 - 2.7e-06 26.8 19.3 2.7e-06 26.8 19.3 2.2 1 1 1 2 2 2 1 Ion transport protein PKD_channel PF08016.12 OQS07829.1 - 8.8e-06 24.6 7.5 8.8e-06 24.6 7.5 2.2 1 1 0 1 1 1 1 Polycystin cation channel Telomere_reg-2 PF10193.9 OQS07829.1 - 0.32 11.5 3.7 0.22 12.0 0.6 2.3 2 1 0 2 2 2 0 Telomere length regulation protein Troponin PF00992.20 OQS07829.1 - 0.82 10.0 6.2 0.21 11.9 0.9 2.0 2 0 0 2 2 2 0 Troponin Hydrolase_2 PF07486.12 OQS07830.1 - 0.14 13.0 1.9 0.25 12.2 1.9 1.4 1 0 0 1 1 1 0 Cell Wall Hydrolase Defensin_propep PF00879.18 OQS07830.1 - 0.47 10.8 5.1 1.4 9.2 5.1 1.7 1 0 0 1 1 1 0 Defensin propeptide HAUS6_N PF14661.6 OQS07831.1 - 0.0015 18.1 5.6 0.0015 18.1 5.6 1.7 2 0 0 2 2 2 1 HAUS augmin-like complex subunit 6 N-terminus Glyco_transf_10 PF00852.19 OQS07831.1 - 0.016 15.0 0.1 0.027 14.2 0.1 1.3 1 0 0 1 1 1 0 Glycosyltransferase family 10 (fucosyltransferase) C-term DUF919 PF06034.11 OQS07831.1 - 0.12 12.2 8.5 0.09 12.6 5.8 2.3 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF919) LOH1CR12 PF10158.9 OQS07831.1 - 0.23 11.5 3.4 1.6 8.8 0.7 3.0 3 0 0 3 3 3 0 Tumour suppressor protein DUF501 PF04417.12 OQS07832.1 - 4.7e-40 136.6 0.2 6e-40 136.3 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF501) DUF641 PF04859.12 OQS07833.1 - 0.0086 16.4 2.7 0.0086 16.4 2.7 5.3 4 1 1 5 5 5 2 Plant protein of unknown function (DUF641) tRNA-synt_1e PF01406.19 OQS07834.1 - 6.6e-103 344.2 0.1 1.1e-102 343.5 0.1 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain COPIIcoated_ERV PF07970.12 OQS07834.1 - 4.9e-68 229.3 0.2 8.2e-68 228.6 0.2 1.4 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 OQS07834.1 - 1.8e-25 89.1 0.0 4e-25 88.0 0.0 1.6 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) tRNA-synt_1g PF09334.11 OQS07834.1 - 7.5e-10 38.1 0.8 0.0006 18.7 0.1 2.2 2 0 0 2 2 2 2 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 OQS07834.1 - 0.04 12.2 0.0 0.13 10.5 0.0 1.7 2 0 0 2 2 2 0 tRNA synthetases class I (I, L, M and V) DALR_2 PF09190.11 OQS07834.1 - 0.051 14.1 0.0 0.14 12.7 0.0 1.8 1 0 0 1 1 1 0 DALR domain eIF2_C PF09173.11 OQS07835.1 - 1.3e-36 124.7 0.6 3.5e-36 123.3 0.6 1.8 1 0 0 1 1 1 1 Initiation factor eIF2 gamma, C terminal GTP_EFTU PF00009.27 OQS07835.1 - 3.1e-23 82.3 1.2 2.5e-22 79.4 1.2 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 OQS07835.1 - 2.4e-13 50.3 0.6 6.2e-13 48.9 0.6 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 OQS07835.1 - 0.004 17.2 0.2 0.012 15.7 0.0 1.9 2 1 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 OQS07835.1 - 0.0059 16.5 0.3 0.097 12.6 0.1 2.4 2 0 0 2 2 2 1 RsgA GTPase Glyco_transf_52 PF07922.11 OQS07835.1 - 0.13 11.5 0.0 0.21 10.8 0.0 1.3 1 0 0 1 1 1 0 Glycosyltransferase family 52 MMR_HSR1_Xtn PF16897.5 OQS07835.1 - 0.15 12.1 0.1 0.34 10.9 0.1 1.6 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain Dynamin_N PF00350.23 OQS07835.1 - 0.2 11.7 1.1 0.39 10.7 0.2 2.0 2 1 0 2 2 2 0 Dynamin family Snf7 PF03357.21 OQS07836.1 - 5.1e-10 39.2 9.8 6.6e-10 38.8 9.2 1.5 1 1 0 1 1 1 1 Snf7 Tropomyosin_1 PF12718.7 OQS07836.1 - 9.4e-06 25.8 1.8 9.4e-06 25.8 1.8 2.3 1 1 1 2 2 2 1 Tropomyosin like EF-hand_1 PF00036.32 OQS07837.1 - 3.2e-127 404.9 72.5 1.8e-06 27.1 0.6 26.8 26 0 0 26 26 26 25 EF hand EF-hand_7 PF13499.6 OQS07837.1 - 3.5e-112 367.0 59.9 8.3e-11 42.2 0.0 15.6 15 0 0 15 15 15 14 EF-hand domain pair EF-hand_6 PF13405.6 OQS07837.1 - 3e-105 335.3 86.6 1.1e-05 24.9 0.4 27.9 27 0 0 27 27 27 24 EF-hand domain EF-hand_8 PF13833.6 OQS07837.1 - 5.3e-69 227.9 61.5 2e-05 24.4 0.0 21.6 15 6 6 21 21 21 20 EF-hand domain pair EF-hand_5 PF13202.6 OQS07837.1 - 6.4e-64 208.8 70.3 0.00028 20.2 0.1 23.9 25 0 0 25 25 25 17 EF hand EF-hand_9 PF14658.6 OQS07837.1 - 8.6e-10 38.8 4.7 0.45 10.9 0.1 10.0 10 2 2 12 12 12 2 EF-hand domain Caleosin PF05042.13 OQS07837.1 - 1.5e-07 31.5 28.4 1.3 8.9 0.0 11.7 13 3 1 14 14 14 4 Caleosin related protein SPARC_Ca_bdg PF10591.9 OQS07837.1 - 2.7e-06 27.7 17.7 9 6.7 0.0 10.9 10 1 2 12 12 12 2 Secreted protein acidic and rich in cysteine Ca binding region DUF5338 PF17273.2 OQS07837.1 - 2.3e-05 24.4 0.0 32 4.7 0.0 7.1 7 0 0 7 7 7 0 Family of unknown function (DUF5338) EF-hand_10 PF14788.6 OQS07837.1 - 0.0075 16.1 4.0 0.45 10.4 0.3 4.9 4 0 0 4 4 4 1 EF hand C2-C2_1 PF11618.8 OQS07837.1 - 0.18 11.8 2.3 7 6.7 0.4 2.7 2 0 0 2 2 2 0 First C2 domain of RPGR-interacting protein 1 Pkinase PF00069.25 OQS07838.1 - 1.2e-33 116.6 0.0 1.8e-33 116.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQS07838.1 - 4.2e-32 111.5 0.0 5.8e-32 111.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase MaoC_dehydratas PF01575.19 OQS07838.1 - 9e-31 106.0 0.0 1.7e-30 105.1 0.0 1.4 1 0 0 1 1 1 1 MaoC like domain MaoC_dehydrat_N PF13452.6 OQS07838.1 - 1.3e-08 35.0 0.0 5.4e-06 26.6 0.0 2.5 2 1 0 2 2 2 2 N-terminal half of MaoC dehydratase Methyltransf_31 PF13847.6 OQS07838.1 - 2.2e-05 24.3 0.0 4.9e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OQS07838.1 - 0.00042 21.0 0.0 0.0011 19.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OQS07838.1 - 0.032 14.9 0.0 0.11 13.2 0.0 2.0 2 0 0 2 2 1 0 Methyltransferase domain Kdo PF06293.14 OQS07838.1 - 0.05 13.0 0.1 0.081 12.3 0.1 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DOT1 PF08123.13 OQS07838.1 - 0.069 12.7 0.0 0.17 11.4 0.0 1.7 1 1 0 1 1 1 0 Histone methylation protein DOT1 IQ PF00612.27 OQS07838.1 - 0.099 12.5 0.1 0.35 10.8 0.1 1.9 2 0 0 2 2 2 0 IQ calmodulin-binding motif PrmA PF06325.13 OQS07838.1 - 0.12 11.7 0.0 0.2 11.0 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_23 PF13489.6 OQS07838.1 - 0.16 11.8 0.0 0.3 10.9 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain E3_UFM1_ligase PF09743.9 OQS07839.1 - 1.6e-79 267.3 1.7 1.7e-79 267.3 0.0 2.0 3 0 0 3 3 3 1 E3 UFM1-protein ligase 1 SKG6 PF08693.10 OQS07841.1 - 4.8e-07 29.1 2.1 7.8e-07 28.4 2.1 1.4 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Adeno_E3_CR2 PF02439.15 OQS07841.1 - 9.6e-05 22.1 1.1 0.00019 21.1 1.1 1.4 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 DUF3827 PF12877.7 OQS07841.1 - 0.0098 14.3 0.1 0.013 13.9 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3827) DUF4448 PF14610.6 OQS07841.1 - 0.011 15.6 0.1 0.011 15.5 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) AMA-1 PF02430.15 OQS07841.1 - 0.032 13.2 0.3 0.045 12.7 0.3 1.2 1 0 0 1 1 1 0 Apical membrane antigen 1 LRR_6 PF13516.6 OQS07841.1 - 0.2 11.8 4.1 2.4 8.4 0.0 3.0 3 0 0 3 3 3 0 Leucine Rich repeat EphA2_TM PF14575.6 OQS07841.1 - 1 10.3 3.2 1.9 9.4 3.2 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Hist_deacetyl PF00850.19 OQS07842.1 - 4.7e-68 229.9 0.0 7.9e-68 229.2 0.0 1.4 1 0 0 1 1 1 1 Histone deacetylase domain Autophagy_N PF03986.13 OQS07842.1 - 4.6e-39 133.5 0.0 1.2e-38 132.1 0.0 1.7 1 0 0 1 1 1 1 Autophagocytosis associated protein (Atg3), N-terminal domain Autophagy_act_C PF03987.15 OQS07842.1 - 3.1e-18 66.1 0.5 1.1e-17 64.4 0.5 2.0 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain Autophagy_C PF10381.9 OQS07842.1 - 5.7e-14 51.3 4.2 1.1e-13 50.4 4.2 1.5 1 0 0 1 1 1 1 Autophagocytosis associated protein C-terminal PHD PF00628.29 OQS07842.1 - 5.5e-09 35.8 2.3 5.5e-09 35.8 2.3 2.0 2 0 0 2 2 2 1 PHD-finger FANCL_C PF11793.8 OQS07842.1 - 0.035 14.3 0.7 0.089 13.0 0.7 1.6 1 0 0 1 1 1 0 FANCL C-terminal domain Lipocalin_3 PF12702.7 OQS07842.1 - 0.059 13.5 0.0 18 5.5 0.0 2.5 2 0 0 2 2 2 0 Lipocalin-like zf-RING-like PF08746.11 OQS07842.1 - 0.29 11.5 1.5 6.8 7.1 0.1 2.6 2 0 0 2 2 2 0 RING-like domain Ank_2 PF12796.7 OQS07843.1 - 3.3e-72 239.1 43.0 4.2e-15 56.1 0.4 7.9 2 1 8 10 10 10 9 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OQS07843.1 - 9.1e-53 170.1 19.3 7.4e-05 22.9 0.0 12.8 13 0 0 13 13 12 10 Ankyrin repeat Ank PF00023.30 OQS07843.1 - 3.9e-52 172.5 47.3 3.2e-07 30.5 0.7 12.4 12 1 1 13 13 12 10 Ankyrin repeat Ank_4 PF13637.6 OQS07843.1 - 1e-50 169.4 14.0 5.1e-08 33.3 0.0 9.8 5 2 4 10 10 10 9 Ankyrin repeats (many copies) Pkinase_Tyr PF07714.17 OQS07843.1 - 1.6e-48 165.2 0.0 3e-48 164.4 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OQS07843.1 - 4.3e-45 154.1 0.0 9.5e-45 153.0 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Ank_5 PF13857.6 OQS07843.1 - 1.3e-36 124.1 26.6 2.5e-06 27.6 0.1 10.2 4 1 7 11 11 11 9 Ankyrin repeats (many copies) Imm_superinfect PF14373.6 OQS07843.1 - 0.0062 16.4 0.5 22 5.0 0.0 4.7 6 0 0 6 6 6 0 Superinfection immunity protein Pkinase_fungal PF17667.1 OQS07843.1 - 0.022 13.5 0.0 0.039 12.7 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase PK_C PF02887.16 OQS07843.1 - 0.072 13.3 0.0 5.8 7.2 0.0 3.1 3 0 0 3 3 3 0 Pyruvate kinase, alpha/beta domain Haspin_kinase PF12330.8 OQS07843.1 - 0.078 11.9 0.1 0.25 10.2 0.1 1.8 1 1 0 1 1 1 0 Haspin like kinase domain Ribosomal_S4e PF00900.20 OQS07843.1 - 0.18 11.8 0.6 42 4.1 0.0 3.7 3 1 1 4 4 4 0 Ribosomal family S4e GTP_EFTU PF00009.27 OQS07845.1 - 4.2e-31 108.0 1.4 4.3e-30 104.7 0.2 2.5 3 0 0 3 3 3 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 OQS07845.1 - 2.2e-09 37.6 0.5 2.2e-09 37.6 0.5 2.4 3 0 0 3 3 3 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 OQS07845.1 - 4.6e-07 29.9 0.2 1e-06 28.8 0.2 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 OQS07845.1 - 0.00072 19.0 0.3 0.0019 17.7 0.3 1.7 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit RIBIOP_C PF04950.12 OQS07845.1 - 0.0024 17.3 0.7 0.34 10.3 0.2 2.4 2 1 0 2 2 2 2 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal FeoB_N PF02421.18 OQS07845.1 - 0.0051 16.3 4.3 1.1 8.8 0.0 3.3 3 1 0 3 3 3 2 Ferrous iron transport protein B cobW PF02492.19 OQS07845.1 - 0.025 14.2 0.4 0.21 11.1 0.1 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain ATP_bind_1 PF03029.17 OQS07845.1 - 0.057 13.2 2.9 6.1 6.6 0.0 3.1 2 1 1 3 3 3 0 Conserved hypothetical ATP binding protein Methyltransf_5 PF01795.19 OQS07845.1 - 0.059 12.9 0.0 0.11 11.9 0.0 1.4 1 0 0 1 1 1 0 MraW methylase family G-alpha PF00503.20 OQS07845.1 - 0.08 12.1 0.0 4 6.5 0.0 2.3 2 0 0 2 2 2 0 G-protein alpha subunit Pkinase_Tyr PF07714.17 OQS07846.1 - 6e-35 120.8 0.2 3e-31 108.6 0.1 3.0 2 1 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 OQS07846.1 - 9e-35 120.3 0.3 6.1e-31 107.8 0.1 2.8 2 1 0 2 2 2 2 Protein kinase domain Pex2_Pex12 PF04757.14 OQS07846.1 - 0.015 14.9 0.0 0.021 14.4 0.0 1.3 1 0 0 1 1 1 0 Pex2 / Pex12 amino terminal region RWD PF05773.22 OQS07847.1 - 2e-05 24.9 0.6 0.00013 22.2 0.4 2.3 2 0 0 2 2 2 1 RWD domain zf-RING_11 PF17123.5 OQS07847.1 - 0.0031 17.2 0.0 0.0091 15.7 0.0 1.9 1 0 0 1 1 1 1 RING-like zinc finger zf-rbx1 PF12678.7 OQS07847.1 - 0.019 15.2 3.2 0.053 13.8 3.2 1.8 1 0 0 1 1 1 0 RING-H2 zinc finger domain PHD PF00628.29 OQS07847.1 - 0.081 12.8 1.5 0.32 10.9 1.5 2.1 1 0 0 1 1 1 0 PHD-finger DUF4218 PF13960.6 OQS07847.1 - 0.09 12.4 0.0 3.7 7.2 0.0 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4218) zf-RING_UBOX PF13445.6 OQS07847.1 - 0.13 12.3 2.2 0.26 11.3 1.1 2.1 1 1 0 1 1 1 0 RING-type zinc-finger zf-RING_2 PF13639.6 OQS07847.1 - 0.24 11.8 6.9 0.56 10.6 4.5 2.8 2 1 0 2 2 2 0 Ring finger domain zf-ANAPC11 PF12861.7 OQS07847.1 - 0.86 9.7 5.2 0.37 10.9 1.9 2.0 2 1 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.6 OQS07847.1 - 2.1 8.4 5.9 1.2 9.1 2.7 2.2 2 0 0 2 2 2 0 zinc-RING finger domain Pkinase_Tyr PF07714.17 OQS07849.1 - 3.4e-23 82.3 1.1 1.3e-21 77.1 1.1 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OQS07849.1 - 1.6e-20 73.5 1.4 1.2e-19 70.7 1.4 1.9 1 1 0 1 1 1 1 Protein kinase domain Pex2_Pex12 PF04757.14 OQS07849.1 - 0.017 14.7 0.0 0.023 14.3 0.0 1.2 1 0 0 1 1 1 0 Pex2 / Pex12 amino terminal region Haspin_kinase PF12330.8 OQS07849.1 - 0.04 12.8 0.0 0.041 12.8 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain APH PF01636.23 OQS07849.1 - 0.11 12.5 0.1 0.13 12.2 0.1 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family Ank_2 PF12796.7 OQS07850.1 - 2.9e-30 104.7 0.3 5.6e-11 42.9 0.0 3.4 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQS07850.1 - 3.3e-27 94.5 5.9 2.3e-11 44.0 0.0 4.8 4 1 1 5 5 5 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 OQS07850.1 - 3.2e-26 91.0 4.0 3.2e-08 33.7 0.1 4.4 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQS07850.1 - 1.7e-19 67.9 1.0 0.0059 17.0 0.0 6.8 6 0 0 6 6 6 4 Ankyrin repeat Ank PF00023.30 OQS07850.1 - 3.5e-13 49.3 1.5 0.056 13.9 0.3 6.0 6 0 0 6 6 6 3 Ankyrin repeat zf-H2C2_2 PF13465.6 OQS07850.1 - 0.073 13.5 0.8 0.073 13.5 0.8 2.5 2 0 0 2 2 2 0 Zinc-finger double domain zf-C2H2 PF00096.26 OQS07850.1 - 0.086 13.3 1.2 0.42 11.2 0.1 2.8 2 0 0 2 2 2 0 Zinc finger, C2H2 type DUF1843 PF08898.10 OQS07850.1 - 0.23 12.0 0.3 1.6 9.3 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1843) Ricin_B_lectin PF00652.22 OQS07851.1 - 6.4e-17 62.0 1.1 1.8e-09 37.9 0.1 2.7 2 1 0 2 2 2 2 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.6 OQS07851.1 - 1.3e-06 29.1 0.1 0.068 13.9 0.1 3.1 3 0 0 3 3 3 2 Ricin-type beta-trefoil lectin domain-like CDtoxinA PF03498.14 OQS07851.1 - 0.0006 19.4 0.3 0.86 9.2 0.0 2.9 3 0 0 3 3 3 2 Cytolethal distending toxin A/C domain Ank_2 PF12796.7 OQS07852.1 - 6.5e-24 84.3 22.0 1.1e-07 32.3 0.4 5.6 1 1 5 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQS07852.1 - 2.3e-22 79.1 23.5 5.7e-06 26.8 0.2 8.6 6 3 2 8 8 8 6 Ankyrin repeats (many copies) Ank_5 PF13857.6 OQS07852.1 - 1.1e-19 70.3 23.9 0.00097 19.4 0.2 10.7 3 2 9 12 12 12 8 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQS07852.1 - 1.3e-16 59.0 11.2 1.8 9.4 0.0 11.0 10 2 2 12 12 12 4 Ankyrin repeat Ank PF00023.30 OQS07852.1 - 0.0017 18.7 14.8 16 6.1 0.0 8.4 4 4 3 7 7 7 1 Ankyrin repeat DDRGK PF09756.9 OQS07852.1 - 0.091 12.3 0.1 0.66 9.5 0.1 2.1 2 1 0 2 2 2 0 DDRGK domain TMEM174 PF15029.6 OQS07853.1 - 1.7 8.3 5.8 0.53 10.0 0.2 2.3 2 0 0 2 2 2 0 Transmembrane protein 174 CHAP PF05257.16 OQS07854.1 - 4.5e-08 33.5 0.6 6.9e-08 33.0 0.6 1.3 1 0 0 1 1 1 1 CHAP domain HET-S PF17108.5 OQS07854.1 - 0.88 9.4 0.1 0.88 9.4 0.1 2.5 3 0 0 3 3 3 0 N-terminal small S protein of HET, non-prionic Pkinase PF00069.25 OQS07855.1 - 2.9e-17 62.9 0.0 3.8e-17 62.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQS07855.1 - 4.8e-05 22.8 0.0 6.4e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 OQS07855.1 - 0.011 15.7 0.0 0.015 15.2 0.0 1.1 1 0 0 1 1 1 0 Phosphotransferase enzyme family TPPII_N PF12583.8 OQS07855.1 - 0.17 12.5 5.3 0.22 12.1 5.3 1.3 1 0 0 1 1 1 0 Tripeptidyl peptidase II N terminal BT1 PF03092.16 OQS07857.1 - 3.3e-06 25.6 0.3 3.3e-06 25.6 0.3 2.8 3 0 0 3 3 3 2 BT1 family PUCC PF03209.15 OQS07857.1 - 0.00021 20.5 1.0 0.00021 20.5 1.0 2.4 2 0 0 2 2 2 1 PUCC protein DUF1118 PF06549.12 OQS07857.1 - 0.23 11.8 0.5 5.9 7.2 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1118) SKA1 PF07160.12 OQS07858.1 - 0.00097 19.0 3.8 0.0012 18.8 3.8 1.2 1 0 0 1 1 1 1 Spindle and kinetochore-associated protein 1 She9_MDM33 PF05546.11 OQS07858.1 - 0.026 14.3 4.7 0.036 13.9 4.7 1.2 1 0 0 1 1 1 0 She9 / Mdm33 family zf-CRD PF17979.1 OQS07858.1 - 0.027 14.6 1.2 0.037 14.1 1.2 1.2 1 0 0 1 1 1 0 Cysteine rich domain with multizinc binding regions Phage_int_SAM_1 PF02899.17 OQS07858.1 - 0.029 14.7 3.0 0.069 13.5 3.0 1.6 1 0 0 1 1 1 0 Phage integrase, N-terminal SAM-like domain MRP-S27 PF10037.9 OQS07858.1 - 0.032 13.1 7.4 0.039 12.8 7.4 1.1 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S27 zf-C4H2 PF10146.9 OQS07858.1 - 0.077 13.3 4.6 0.12 12.7 4.6 1.3 1 0 0 1 1 1 0 Zinc finger-containing protein DUF4164 PF13747.6 OQS07858.1 - 0.11 12.7 15.3 0.044 14.1 12.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4164) HAUS-augmin3 PF14932.6 OQS07858.1 - 0.14 11.7 14.4 0.22 11.1 14.4 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 DUF1664 PF07889.12 OQS07858.1 - 0.16 12.0 5.0 0.28 11.2 5.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Phage_GPO PF05929.11 OQS07858.1 - 0.22 11.1 5.3 0.31 10.6 5.3 1.4 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase THOC7 PF05615.13 OQS07858.1 - 0.32 11.3 13.2 1.4 9.2 12.8 1.9 1 1 1 2 2 2 0 Tho complex subunit 7 Prominin PF05478.11 OQS07858.1 - 0.37 8.7 7.0 0.45 8.4 7.0 1.1 1 0 0 1 1 1 0 Prominin FUSC PF04632.12 OQS07858.1 - 0.88 8.0 6.4 1.1 7.7 6.4 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family TEX13 PF15186.6 OQS07858.1 - 2.3 7.9 12.1 2.3 7.9 10.8 1.7 1 1 0 1 1 1 0 Testis-expressed sequence 13 protein family HTH_31 PF13560.6 OQS07858.1 - 5.5 7.4 8.6 4.8 7.6 0.5 2.7 3 0 0 3 3 3 0 Helix-turn-helix domain YabA PF06156.13 OQS07858.1 - 6.7 7.4 14.3 35 5.1 11.3 2.4 2 1 1 3 3 3 0 Initiation control protein YabA Exonuc_VII_L PF02601.15 OQS07858.1 - 6.7 6.2 9.3 9 5.8 9.3 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit Ank_4 PF13637.6 OQS07859.1 - 1.6e-13 50.8 3.7 3.8e-06 27.3 0.1 3.6 2 2 1 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 OQS07859.1 - 1.6e-11 44.6 0.3 5.9e-07 30.0 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OQS07859.1 - 8.2e-10 38.8 3.4 0.011 16.0 0.0 4.8 1 1 4 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQS07859.1 - 2.5e-06 27.4 0.4 5.7 7.8 0.0 5.2 4 1 1 5 5 5 1 Ankyrin repeat Ank PF00023.30 OQS07859.1 - 0.022 15.2 2.3 14 6.3 1.2 4.3 1 1 1 2 2 2 0 Ankyrin repeat DUF4750 PF15938.5 OQS07860.1 - 5.4e-16 58.0 0.5 6.7e-16 57.7 0.5 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4750) UBA PF00627.31 OQS07861.1 - 0.056 13.4 1.0 0.096 12.6 1.0 1.4 1 0 0 1 1 1 0 UBA/TS-N domain Pkinase_Tyr PF07714.17 OQS07862.1 - 1.6e-23 83.3 0.0 8.1e-17 61.3 0.0 2.8 2 1 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 OQS07862.1 - 1.6e-21 76.9 0.0 5.2e-20 71.9 0.0 2.6 1 1 0 1 1 1 1 Protein kinase domain CO_deh_flav_C PF03450.17 OQS07862.1 - 0.02 15.1 0.0 0.043 14.0 0.0 1.5 1 0 0 1 1 1 0 CO dehydrogenase flavoprotein C-terminal domain CMD PF02627.20 OQS07863.1 - 2e-06 27.7 0.9 3.9e-06 26.8 0.9 1.5 1 0 0 1 1 1 1 Carboxymuconolactone decarboxylase family CpeS PF09367.10 OQS07863.1 - 0.042 13.8 0.0 0.069 13.1 0.0 1.3 1 0 0 1 1 1 0 CpeS-like protein LPD39 PF18858.1 OQS07864.1 - 0.15 12.2 5.3 0.36 10.9 4.5 1.9 1 1 1 2 2 2 0 Large polyvalent protein associated domain 39 Prok-TraM PF09228.10 OQS07864.1 - 0.39 11.1 2.7 8.6 6.8 0.2 2.5 2 0 0 2 2 2 0 Prokaryotic Transcriptional repressor TraM WW PF00397.26 OQS07865.1 - 3.7e-07 30.1 2.1 6.9e-07 29.2 2.1 1.5 1 0 0 1 1 1 1 WW domain MMADHC PF10229.9 OQS07865.1 - 0.06 13.1 0.3 0.11 12.2 0.0 1.5 1 1 1 2 2 2 0 Methylmalonic aciduria and homocystinuria type D protein Pellino PF04710.14 OQS07867.1 - 4.1e-52 177.3 0.0 2.6e-31 108.7 0.0 2.1 2 0 0 2 2 2 2 Pellino zf-C3HC4_3 PF13920.6 OQS07867.1 - 0.0018 18.1 0.2 0.0018 18.1 0.2 3.9 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OQS07867.1 - 0.0068 16.4 6.7 1 9.5 0.2 3.7 2 1 0 2 2 2 2 RING-type zinc-finger zf-RING_2 PF13639.6 OQS07867.1 - 0.018 15.3 14.4 0.076 13.4 0.2 3.4 3 0 0 3 3 3 0 Ring finger domain Prok-RING_4 PF14447.6 OQS07867.1 - 0.025 14.4 0.3 0.025 14.4 0.3 3.5 3 1 0 3 3 3 0 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 OQS07867.1 - 0.076 13.0 12.6 0.087 12.8 0.3 3.4 3 1 0 3 3 3 0 zinc-RING finger domain DUF3039 PF11238.8 OQS07867.1 - 0.9 9.4 4.8 1.4 8.7 0.2 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3039) Ank_4 PF13637.6 OQS07868.1 - 7.8e-18 64.6 2.4 4.6e-07 30.3 0.1 4.1 3 1 0 4 4 4 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 OQS07868.1 - 1e-16 61.3 1.2 2.7e-10 40.7 0.4 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OQS07868.1 - 5.8e-14 52.0 3.6 0.0044 17.3 0.1 5.1 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQS07868.1 - 1.9e-10 40.0 0.7 0.12 13.0 0.0 5.2 4 1 1 5 5 5 3 Ankyrin repeat DUF5049 PF16468.5 OQS07868.1 - 2.1e-05 24.3 3.3 0.94 9.4 0.0 5.5 1 1 5 6 6 6 2 Domain of unknown function (DUF5049) Ank PF00023.30 OQS07868.1 - 5e-05 23.6 0.7 17 6.1 0.0 4.8 1 1 3 4 4 4 2 Ankyrin repeat Glycos_transf_1 PF00534.20 OQS07869.1 - 1.8e-05 24.3 0.0 3.9e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 OQS07869.1 - 0.0043 17.5 0.0 0.0076 16.7 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 DUF667 PF05018.13 OQS07870.1 - 2e-20 73.3 0.0 3.1e-20 72.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF667) OCRE PF17780.1 OQS07870.1 - 0.17 11.9 0.4 2.7 8.1 0.1 2.2 2 0 0 2 2 2 0 OCRE domain PPAK PF02818.15 OQS07870.1 - 0.33 11.1 5.2 1.3 9.2 5.2 2.1 1 0 0 1 1 1 0 PPAK motif Pkinase PF00069.25 OQS07871.1 - 1.1e-39 136.4 0.0 1.6e-39 135.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQS07871.1 - 2.5e-39 135.1 0.0 3.4e-39 134.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OQS07871.1 - 0.0028 17.0 0.0 0.0068 15.7 0.0 1.6 1 0 0 1 1 1 1 Kinase-like DEP PF00610.21 OQS07871.1 - 0.0066 16.5 0.0 0.015 15.3 0.0 1.5 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Kdo PF06293.14 OQS07871.1 - 0.034 13.5 0.0 0.063 12.6 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF1129 PF06570.11 OQS07871.1 - 2.1 7.8 6.1 1.8 8.0 4.1 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1129) Pkinase_Tyr PF07714.17 OQS07872.1 - 1.5e-40 139.1 0.0 2.6e-40 138.3 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OQS07872.1 - 2.3e-40 138.6 0.0 3.8e-40 137.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain DEP PF00610.21 OQS07872.1 - 3.2e-05 23.9 0.0 6.8e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) PGG PF13962.6 OQS07872.1 - 0.03 14.1 8.3 1.8 8.4 5.6 2.9 2 0 0 2 2 2 0 Domain of unknown function APH PF01636.23 OQS07872.1 - 0.1 12.5 0.0 0.18 11.7 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family DEP PF00610.21 OQS07873.1 - 4e-09 36.4 0.1 7.5e-09 35.5 0.1 1.5 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Glyco_hydro_79n PF03662.14 OQS07873.1 - 0.072 12.0 0.0 0.097 11.6 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 79, N-terminal domain DDE_1 PF03184.19 OQS07874.1 - 6.6e-09 35.7 0.0 1.1e-08 35.0 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease CENP-B_N PF04218.13 OQS07874.1 - 1.6e-06 27.6 1.8 3.5e-06 26.5 1.8 1.6 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain HTH_Tnp_Tc5 PF03221.16 OQS07874.1 - 8.4e-06 25.7 0.0 1.7e-05 24.7 0.0 1.5 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain HTH_Tnp_1_2 PF13022.6 OQS07874.1 - 0.033 14.3 0.9 0.092 12.9 0.4 1.9 1 1 1 2 2 2 0 Helix-turn-helix of insertion element transposase ACP_PD PF04336.12 OQS07874.1 - 0.036 14.5 0.2 4.8 7.6 0.0 3.2 3 1 1 4 4 4 0 Acyl carrier protein phosphodiesterase HTH_23 PF13384.6 OQS07874.1 - 0.044 13.6 0.1 0.13 12.1 0.1 1.7 1 0 0 1 1 1 0 Homeodomain-like domain HTH_28 PF13518.6 OQS07874.1 - 0.051 13.7 0.0 0.14 12.3 0.0 1.8 1 0 0 1 1 1 0 Helix-turn-helix domain UPF0122 PF04297.14 OQS07874.1 - 0.063 13.5 0.3 0.17 12.1 0.2 1.7 1 1 0 1 1 1 0 Putative helix-turn-helix protein, YlxM / p13 like HTH_38 PF13936.6 OQS07874.1 - 0.064 13.0 0.2 0.17 11.7 0.2 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain Sigma70_r4 PF04545.16 OQS07874.1 - 0.075 12.6 0.0 0.15 11.6 0.0 1.5 1 0 0 1 1 1 0 Sigma-70, region 4 UCH PF00443.29 OQS07875.1 - 2.2e-34 119.1 0.1 3.7e-34 118.4 0.1 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 OQS07875.1 - 1e-13 51.4 0.5 1.9e-13 50.5 0.5 1.5 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein Armet PF10208.9 OQS07875.1 - 0.00033 20.6 0.0 0.00092 19.2 0.0 1.7 1 0 0 1 1 1 1 Degradation arginine-rich protein for mis-folding UCH_1 PF13423.6 OQS07875.1 - 0.0033 17.1 0.0 0.046 13.3 0.0 2.4 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUF383 PF04063.14 OQS07875.1 - 0.068 12.8 0.0 0.13 11.9 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF383) TFA2_Winged_2 PF18121.1 OQS07876.1 - 5.5e-08 32.4 0.0 1.6e-07 30.9 0.0 1.8 2 0 0 2 2 2 1 TFA2 Winged helix domain 2 Semenogelin PF05474.11 OQS07876.1 - 0.0085 14.7 0.1 0.012 14.2 0.1 1.1 1 0 0 1 1 1 1 Semenogelin BSD PF03909.17 OQS07877.1 - 3.6e-14 52.5 1.0 6.4e-11 42.1 0.2 3.2 2 0 0 2 2 2 2 BSD domain MAGE PF01454.19 OQS07877.1 - 0.0019 18.0 0.1 0.0062 16.3 0.1 1.9 1 0 0 1 1 1 1 MAGE family SAM_LFY PF01698.16 OQS07877.1 - 0.0076 16.2 0.0 0.022 14.7 0.0 1.8 1 0 0 1 1 1 1 Floricaula / Leafy protein SAM domain PH_TFIIH PF08567.11 OQS07877.1 - 0.015 15.6 0.0 0.046 14.0 0.0 1.9 1 0 0 1 1 1 0 TFIIH p62 subunit, N-terminal domain Globin PF00042.22 OQS07877.1 - 0.044 14.3 2.1 23 5.6 0.0 3.7 3 1 1 4 4 4 0 Globin ATP-synt_E PF05680.12 OQS07877.1 - 0.65 10.4 5.3 0.46 10.9 0.4 3.1 2 1 0 2 2 2 0 ATP synthase E chain IMS PF00817.20 OQS07878.1 - 3.3e-42 144.0 0.9 1.7e-41 141.7 0.4 2.3 2 0 0 2 2 2 1 impB/mucB/samB family IMS_C PF11799.8 OQS07878.1 - 1.7e-09 38.4 1.0 4.1e-09 37.2 1.0 1.6 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain RNF220 PF15926.5 OQS07878.1 - 5.1e-07 29.6 20.9 0.02 14.6 0.7 3.9 2 2 1 3 3 3 3 E3 ubiquitin-protein ligase RNF220 IMS_HHH PF11798.8 OQS07878.1 - 2.4e-06 27.5 0.2 5.7e-06 26.4 0.2 1.7 1 0 0 1 1 1 1 IMS family HHH motif zf-WRNIP1_ubi PF18279.1 OQS07878.1 - 3.5e-06 27.2 10.2 0.0057 17.2 0.1 4.7 4 0 0 4 4 4 2 Werner helicase-interacting protein 1 ubiquitin-binding domain Zn-C2H2_12 PF18112.1 OQS07878.1 - 4.7e-06 27.0 7.8 1.6 9.3 0.2 4.8 4 0 0 4 4 4 3 Autophagy receptor zinc finger-C2H2 domain zf-C2H2_4 PF13894.6 OQS07878.1 - 0.00014 22.4 13.9 0.84 10.6 0.6 4.8 4 0 0 4 4 4 2 C2H2-type zinc finger zf-C2H2_9 PF16293.5 OQS07878.1 - 0.00025 20.8 14.9 0.15 12.0 0.7 4.5 4 0 0 4 4 4 2 C2H2 type zinc-finger (1 copy) zf-Di19 PF05605.12 OQS07878.1 - 0.0094 16.2 18.3 0.68 10.3 4.5 4.2 4 1 0 4 4 4 2 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_12 PF18658.1 OQS07878.1 - 0.011 15.3 11.5 3.4 7.3 0.2 4.4 3 1 1 4 4 4 0 Zinc-finger C2H2-type Rad50_zn_hook PF04423.14 OQS07878.1 - 0.025 14.4 19.5 0.13 12.1 0.1 5.4 5 1 1 6 6 5 0 Rad50 zinc hook motif Prok-RING_4 PF14447.6 OQS07878.1 - 0.028 14.3 11.6 12 5.8 0.1 4.5 4 0 0 4 4 4 0 Prokaryotic RING finger family 4 UBZ_FAAP20 PF15750.5 OQS07878.1 - 0.13 12.2 14.2 1.3 9.1 0.3 4.5 4 0 0 4 4 4 0 Ubiquitin-binding zinc-finger DUF2256 PF10013.9 OQS07878.1 - 0.24 11.5 7.3 4.2 7.6 0.2 4.2 4 0 0 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2256) TRAF6_Z2 PF18048.1 OQS07878.1 - 0.47 10.6 16.7 0.18 11.9 1.2 3.9 4 0 0 4 4 4 0 TNF receptor-associated factor 6 zinc finger 2 zf-TFIIB PF13453.6 OQS07878.1 - 0.84 9.0 13.9 11 5.4 0.3 4.4 4 0 0 4 4 4 0 Transcription factor zinc-finger zf-RVT PF13966.6 OQS07878.1 - 1.1 10.0 7.6 6.9 7.5 0.2 3.5 3 0 0 3 3 3 0 zinc-binding in reverse transcriptase GAGA PF09237.11 OQS07878.1 - 2.3 8.1 12.4 1.5 8.7 0.1 4.2 4 0 0 4 4 4 0 GAGA factor zinc-ribbons_6 PF07191.12 OQS07878.1 - 2.5 8.2 17.5 6 6.9 2.6 3.4 1 1 2 3 3 3 0 zinc-ribbons Prok-RING_1 PF14446.6 OQS07878.1 - 4.1 7.4 13.5 48 4.0 0.1 4.5 3 1 1 4 4 4 0 Prokaryotic RING finger family 1 zf-C2H2 PF00096.26 OQS07878.1 - 4.4 8.0 10.4 41 4.9 0.2 4.5 4 0 0 4 4 4 0 Zinc finger, C2H2 type YdjO PF14169.6 OQS07878.1 - 5 6.9 9.5 6.7 6.5 0.1 3.8 4 0 0 4 4 4 0 Cold-inducible protein YdjO zf-C3HC4_3 PF13920.6 OQS07878.1 - 6.3 6.8 17.3 23 4.9 0.1 4.0 2 1 3 5 5 5 0 Zinc finger, C3HC4 type (RING finger) TPR_2 PF07719.17 OQS07879.1 - 7.3e-10 38.2 0.1 0.58 10.4 0.0 5.3 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_8 PF13181.6 OQS07879.1 - 5.7e-08 32.4 0.0 0.0028 17.8 0.0 4.5 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.6 OQS07879.1 - 1.1e-07 32.3 0.1 0.53 10.8 0.1 3.6 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.28 OQS07879.1 - 7.2e-07 28.8 0.0 0.084 12.7 0.0 4.6 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.6 OQS07879.1 - 3.1e-05 24.4 0.1 3 8.9 0.0 4.6 2 1 2 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.6 OQS07879.1 - 0.00012 22.5 0.0 1.2 9.9 0.0 4.8 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_16 PF13432.6 OQS07879.1 - 0.00045 20.8 0.2 1.2 9.9 0.0 2.8 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.6 OQS07879.1 - 0.00088 19.5 1.9 0.09 13.1 0.1 3.7 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_9 PF13371.6 OQS07879.1 - 0.015 15.4 0.0 2.4 8.4 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat ANAPC3 PF12895.7 OQS07879.1 - 0.055 13.7 0.6 1.3 9.3 0.0 3.1 3 1 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.6 OQS07879.1 - 0.097 12.7 0.0 7.5 6.8 0.0 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat Cyt-b5 PF00173.28 OQS07880.1 - 1e-21 76.8 0.0 1.5e-21 76.3 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DUF1126 PF06565.12 OQS07881.1 - 4.6e-84 277.1 0.3 3e-31 107.4 0.1 3.7 3 0 0 3 3 3 3 DUF1126 PH-like domain zf-RanBP PF00641.18 OQS07882.1 - 0.0002 20.6 3.6 0.00036 19.8 3.6 1.4 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others DZR PF12773.7 OQS07882.1 - 0.099 12.7 1.0 0.17 11.9 1.0 1.4 1 0 0 1 1 1 0 Double zinc ribbon NIF PF03031.18 OQS07884.1 - 1.5e-55 187.2 0.3 2.1e-55 186.8 0.3 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase HSF_DNA-bind PF00447.17 OQS07886.1 - 3.8e-18 65.9 0.0 6.5e-18 65.1 0.0 1.4 1 0 0 1 1 1 1 HSF-type DNA-binding TPR_1 PF00515.28 OQS07887.1 - 7.3e-48 158.5 41.8 7e-06 25.6 0.0 14.0 14 0 0 14 14 14 9 Tetratricopeptide repeat TPR_2 PF07719.17 OQS07887.1 - 5.6e-42 138.5 33.8 0.0012 18.8 0.0 15.6 16 0 0 16 16 16 9 Tetratricopeptide repeat TPR_11 PF13414.6 OQS07887.1 - 9.1e-28 95.7 23.6 0.0022 17.6 0.0 12.6 9 3 4 13 13 13 9 TPR repeat TPR_12 PF13424.6 OQS07887.1 - 2e-22 79.3 27.4 3.9e-05 23.9 0.4 10.6 9 4 2 11 11 10 5 Tetratricopeptide repeat TPR_8 PF13181.6 OQS07887.1 - 5.1e-22 76.2 33.1 0.00036 20.5 0.1 13.8 15 0 0 15 15 15 4 Tetratricopeptide repeat TPR_9 PF13371.6 OQS07887.1 - 1.7e-17 63.4 0.3 0.013 15.6 0.0 8.0 6 2 2 8 8 8 4 Tetratricopeptide repeat TPR_14 PF13428.6 OQS07887.1 - 2.6e-13 49.6 0.7 0.17 12.8 0.0 10.4 6 3 5 11 11 11 1 Tetratricopeptide repeat TPR_16 PF13432.6 OQS07887.1 - 1.3e-12 48.1 3.2 0.047 14.3 0.0 8.3 7 2 3 10 10 9 3 Tetratricopeptide repeat TPR_19 PF14559.6 OQS07887.1 - 1.6e-11 44.5 9.2 0.048 14.2 0.2 7.7 5 3 6 11 11 11 5 Tetratricopeptide repeat TPR_7 PF13176.6 OQS07887.1 - 1.7e-11 43.3 11.4 0.00065 19.5 0.0 8.8 9 1 1 10 10 8 2 Tetratricopeptide repeat TPR_17 PF13431.6 OQS07887.1 - 2.3e-11 43.2 34.0 1.7 9.2 0.2 12.5 14 0 0 14 14 14 3 Tetratricopeptide repeat ANAPC3 PF12895.7 OQS07887.1 - 1.7e-10 40.9 33.5 0.00064 19.9 0.0 7.9 6 2 3 9 9 9 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.6 OQS07887.1 - 1.3e-08 34.4 17.9 0.23 11.4 0.0 7.8 9 0 0 9 9 8 3 Tetratricopeptide repeat TPR_6 PF13174.6 OQS07887.1 - 2e-05 24.9 30.6 1 10.1 0.2 12.2 14 0 0 14 14 12 1 Tetratricopeptide repeat TPR_15 PF13429.6 OQS07887.1 - 0.0002 20.7 11.6 0.17 11.0 0.3 5.1 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_MalT PF17874.1 OQS07887.1 - 0.00052 19.5 7.8 0.19 11.1 0.1 4.6 3 1 0 4 4 4 1 MalT-like TPR region TPR_21 PF09976.9 OQS07887.1 - 0.05 13.3 1.0 1.7 8.3 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat-like domain ChAPs PF09295.10 OQS07887.1 - 0.053 12.5 5.7 0.44 9.5 0.4 3.6 4 0 0 4 4 4 0 ChAPs (Chs5p-Arf1p-binding proteins) SHNi-TPR PF10516.9 OQS07887.1 - 0.24 10.9 8.8 20 4.8 0.0 5.5 6 0 0 6 6 6 0 SHNi-TPR SRP_TPR_like PF17004.5 OQS07887.1 - 0.73 9.9 10.2 0.1 12.7 1.5 3.3 3 1 0 3 3 2 0 Putative TPR-like repeat MIT PF04212.18 OQS07887.1 - 0.92 9.6 13.8 13 5.9 0.0 6.9 7 1 1 8 8 7 0 MIT (microtubule interacting and transport) domain SNF2_N PF00176.23 OQS07888.1 - 2.1e-34 118.8 4.8 7.4e-34 117.0 2.5 2.3 1 1 1 2 2 2 1 SNF2 family N-terminal domain ResIII PF04851.15 OQS07888.1 - 1.6e-09 38.0 0.0 1.4e-08 35.0 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 OQS07888.1 - 3.8e-05 24.0 0.0 0.0001 22.6 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 OQS07888.1 - 0.00017 21.4 0.1 0.00075 19.3 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase zf-RING_5 PF14634.6 OQS07888.1 - 0.11 12.4 16.2 0.26 11.3 16.2 1.7 1 0 0 1 1 1 0 zinc-RING finger domain CNOT11 PF10155.9 OQS07888.1 - 0.15 12.2 1.7 3.5 7.8 0.1 3.2 3 0 0 3 3 3 0 CCR4-NOT transcription complex subunit 11 Prok-RING_4 PF14447.6 OQS07888.1 - 1.2 9.0 14.8 3.6 7.5 14.7 1.8 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 14-3-3 PF00244.20 OQS07889.1 - 4.9e-86 287.8 3.7 5.5e-86 287.6 3.7 1.0 1 0 0 1 1 1 1 14-3-3 protein TPR_8 PF13181.6 OQS07889.1 - 0.00063 19.8 0.5 0.13 12.6 0.0 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 OQS07889.1 - 0.0047 16.9 1.9 0.87 9.8 0.0 3.4 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_12 PF13424.6 OQS07889.1 - 0.0049 17.1 2.7 0.17 12.2 0.1 3.3 2 2 1 3 3 3 1 Tetratricopeptide repeat GP44 PF17510.2 OQS07889.1 - 0.017 15.3 0.1 2.8 8.2 0.0 2.7 2 1 1 3 3 3 0 Gene product 44 PI3Ka PF00613.20 OQS07889.1 - 0.037 13.4 0.1 0.058 12.8 0.1 1.3 1 0 0 1 1 1 0 Phosphoinositide 3-kinase family, accessory domain (PIK domain) TPR_11 PF13414.6 OQS07889.1 - 0.076 12.7 0.1 0.24 11.1 0.1 1.8 1 0 0 1 1 1 0 TPR repeat Lar_N PF09861.9 OQS07889.1 - 0.13 11.4 0.1 0.19 10.9 0.1 1.2 1 0 0 1 1 1 0 Lactate racemase N-terminal domain TPR_6 PF13174.6 OQS07889.1 - 1.4 9.7 3.7 61 4.6 0.0 3.7 3 1 0 3 3 3 0 Tetratricopeptide repeat ParcG PF10274.9 OQS07890.1 - 5e-36 124.5 0.0 3.4e-35 121.8 0.0 2.0 1 1 0 1 1 1 1 Parkin co-regulated protein Hid1 PF12722.7 OQS07890.1 - 4.5 5.3 6.0 6.6 4.7 6.0 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein ABC_tran PF00005.27 OQS07891.1 - 8.8e-14 52.2 0.9 6.5e-06 26.7 0.1 2.3 2 0 0 2 2 2 2 ABC transporter AAA_29 PF13555.6 OQS07891.1 - 1.2e-05 25.0 2.9 0.023 14.4 0.2 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 OQS07891.1 - 2.2e-05 24.4 2.2 0.048 13.6 0.1 2.3 2 0 0 2 2 2 2 RsgA GTPase AAA_18 PF13238.6 OQS07891.1 - 0.00051 20.6 0.1 0.099 13.2 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 OQS07891.1 - 0.0029 18.0 0.2 0.15 12.4 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain AAA_25 PF13481.6 OQS07891.1 - 0.0029 17.2 1.6 0.55 9.8 0.2 2.3 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.6 OQS07891.1 - 0.0037 17.5 1.2 0.44 10.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 OQS07891.1 - 0.011 15.5 2.4 2.6 7.7 0.9 2.3 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 OQS07891.1 - 0.013 14.8 2.1 0.24 10.6 0.0 2.2 2 0 0 2 2 2 0 Zeta toxin AAA PF00004.29 OQS07891.1 - 0.016 15.7 0.6 1.5 9.3 0.0 2.9 3 0 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) MMR_HSR1 PF01926.23 OQS07891.1 - 0.018 15.1 0.4 0.86 9.7 0.1 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase NACHT PF05729.12 OQS07891.1 - 0.036 14.0 1.6 2 8.3 0.1 2.4 2 0 0 2 2 2 0 NACHT domain Roc PF08477.13 OQS07891.1 - 0.059 13.6 0.3 0.83 9.9 0.0 2.3 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase DUF815 PF05673.13 OQS07891.1 - 0.059 12.5 0.6 0.12 11.5 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_5 PF07728.14 OQS07891.1 - 0.065 13.2 0.5 0.72 9.9 0.1 2.5 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 OQS07891.1 - 0.09 12.9 0.3 12 6.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain Ploopntkinase3 PF18751.1 OQS07891.1 - 0.11 12.4 0.4 0.42 10.5 0.1 1.9 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 AAA_24 PF13479.6 OQS07891.1 - 0.11 12.2 1.3 11 5.7 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.6 OQS07891.1 - 0.19 12.2 2.3 7.5 7.0 0.1 2.3 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 OQS07891.1 - 0.31 11.0 0.8 19 5.3 0.4 2.4 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_19 PF13245.6 OQS07891.1 - 0.74 10.1 2.5 16 5.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 OQS07891.1 - 0.76 9.3 2.8 1.7 8.1 0.1 2.2 2 0 0 2 2 2 0 P-loop containing dynein motor region RNA_helicase PF00910.22 OQS07891.1 - 1.4 9.3 5.2 4.7 7.6 0.1 2.9 3 0 0 3 3 2 0 RNA helicase DUF87 PF01935.17 OQS07891.1 - 2 8.5 3.5 18 5.3 0.1 2.3 2 0 0 2 2 2 0 Helicase HerA, central domain Peptidase_S8 PF00082.22 OQS07892.1 - 2.3e-41 142.0 0.4 4.2e-41 141.1 0.4 1.4 1 0 0 1 1 1 1 Subtilase family Peripla_BP_1 PF00532.21 OQS07892.1 - 0.027 13.9 0.0 0.056 12.9 0.0 1.5 1 0 0 1 1 1 0 Periplasmic binding proteins and sugar binding domain of LacI family Kelch_1 PF01344.25 OQS07892.1 - 0.084 12.5 0.7 0.31 10.7 0.0 2.3 3 0 0 3 3 3 0 Kelch motif Pkinase PF00069.25 OQS07893.1 - 2.2e-49 168.2 0.0 3.1e-49 167.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQS07893.1 - 1.6e-46 158.7 0.0 2e-46 158.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 OQS07893.1 - 0.00035 20.0 0.0 0.00065 19.1 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 OQS07893.1 - 0.00039 19.3 0.2 0.00061 18.7 0.2 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 OQS07893.1 - 0.039 13.9 0.0 0.072 13.0 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family TMCCDC2 PF15844.5 OQS07893.1 - 0.12 12.3 0.3 0.25 11.2 0.0 1.6 2 0 0 2 2 2 0 Transmembrane and coiled-coil domain-containing protein 2 3-HAO PF06052.12 OQS07894.1 - 0.11 12.1 0.0 0.21 11.2 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyanthranilic acid dioxygenase EamA PF00892.20 OQS07895.1 - 7.6e-08 32.6 19.2 9.3e-07 29.1 3.4 2.4 2 1 1 3 3 3 3 EamA-like transporter family SLATT_1 PF18181.1 OQS07895.1 - 0.015 15.2 0.7 0.033 14.1 0.7 1.5 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain 1 Wzy_C PF04932.15 OQS07895.1 - 7.1 6.2 13.1 6.4e+02 -0.1 13.1 3.0 1 1 0 1 1 1 0 O-Antigen ligase Ank_2 PF12796.7 OQS07896.1 - 2.4e-19 69.7 10.7 2.7e-06 27.9 0.1 4.9 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQS07896.1 - 1.6e-15 57.2 3.5 6.5e-05 23.4 0.0 6.4 6 1 0 6 6 6 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 OQS07896.1 - 5.4e-11 42.5 6.8 0.19 12.1 0.0 8.3 5 2 5 10 10 10 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQS07896.1 - 9.2e-10 37.9 4.6 0.44 11.3 0.0 8.6 6 3 4 10 10 10 2 Ankyrin repeat Ank PF00023.30 OQS07896.1 - 0.0014 18.9 4.4 7.6 7.2 0.0 5.6 5 1 1 6 6 6 2 Ankyrin repeat DUF5049 PF16468.5 OQS07896.1 - 0.25 11.3 0.9 27 4.8 0.0 3.9 4 1 0 4 4 4 0 Domain of unknown function (DUF5049) MutS_V PF00488.21 OQS07897.1 - 2e-31 109.5 0.0 4.9e-31 108.2 0.0 1.6 2 0 0 2 2 2 1 MutS domain V MutS_III PF05192.18 OQS07897.1 - 0.0023 18.2 0.0 0.0023 18.2 0.0 1.1 1 0 0 1 1 1 1 MutS domain III TIR_2 PF13676.6 OQS07898.1 - 1e-18 68.0 0.0 5.8e-11 43.0 0.0 2.8 2 0 0 2 2 2 2 TIR domain AAA_16 PF13191.6 OQS07898.1 - 1.7e-05 25.3 0.0 3.9e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain ATPase_2 PF01637.18 OQS07898.1 - 0.0012 18.8 0.0 0.002 18.1 0.0 1.3 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_29 PF13555.6 OQS07898.1 - 0.015 15.1 0.0 0.031 14.0 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain NACHT PF05729.12 OQS07898.1 - 0.063 13.2 0.0 0.24 11.3 0.0 2.0 2 0 0 2 2 2 0 NACHT domain AAA_14 PF13173.6 OQS07898.1 - 0.13 12.3 0.0 0.26 11.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 OQS07898.1 - 0.18 12.1 0.0 0.81 10.0 0.0 2.2 2 0 0 2 2 2 0 AAA domain KAP_NTPase PF07693.14 OQS07898.1 - 0.19 10.9 0.1 7 5.8 0.0 2.2 1 1 1 2 2 2 0 KAP family P-loop domain G_glu_transpept PF01019.21 OQS07899.1 - 1.4e-93 314.4 0.0 2.6e-68 231.0 0.0 2.0 2 0 0 2 2 2 2 Gamma-glutamyltranspeptidase Piezo_RRas_bdg PF12166.8 OQS07900.1 - 8.2e-71 239.5 0.0 8.2e-71 239.5 0.0 2.3 2 0 0 2 2 2 1 Piezo non-specific cation channel, R-Ras-binding domain HA PF03457.14 OQS07900.1 - 1.8e-21 76.2 0.0 0.0084 16.4 0.0 6.3 6 0 0 6 6 6 5 Helicase associated domain fn3 PF00041.21 OQS07900.1 - 3.6e-13 49.7 0.1 8.9e-13 48.4 0.1 1.8 1 0 0 1 1 1 1 Fibronectin type III domain PH PF00169.29 OQS07900.1 - 2.7e-07 31.1 0.1 7.6e-07 29.6 0.1 1.8 1 0 0 1 1 1 1 PH domain Pur_ac_phosph_N PF16656.5 OQS07900.1 - 0.00049 20.6 0.8 0.0011 19.4 0.1 2.1 2 0 0 2 2 2 1 Purple acid Phosphatase, N-terminal domain Antigen_Bd37 PF11641.8 OQS07900.1 - 0.18 11.3 0.1 5.6 6.4 0.0 2.2 2 0 0 2 2 2 0 Glycosylphosphatidylinositol-anchored merozoite surface protein zf-HIT PF04438.16 OQS07901.1 - 1.8e-09 37.3 11.3 3.9e-09 36.2 11.3 1.5 1 0 0 1 1 1 1 HIT zinc finger SHQ1 PF04925.15 OQS07901.1 - 0.00053 19.6 0.1 0.00089 18.9 0.1 1.4 1 0 0 1 1 1 1 SHQ1 protein DUF3102 PF11300.8 OQS07901.1 - 0.098 12.9 0.2 0.21 11.8 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3102) Lir1 PF07207.11 OQS07901.1 - 0.17 12.1 3.3 2.5 8.4 0.2 2.3 2 0 0 2 2 2 0 Light regulated protein Lir1 PH PF00169.29 OQS07902.1 - 1.5e-09 38.3 0.1 1.2e-08 35.4 0.0 2.2 2 0 0 2 2 2 1 PH domain PH_3 PF14593.6 OQS07902.1 - 3.4e-08 33.5 0.4 1.9e-05 24.7 0.0 2.9 2 1 1 3 3 3 2 PH domain PDZ_6 PF17820.1 OQS07902.1 - 7.6e-06 25.7 0.0 0.25 11.2 0.0 2.9 3 0 0 3 3 3 2 PDZ domain PDZ PF00595.24 OQS07902.1 - 0.0018 18.6 0.0 0.45 10.9 0.0 2.7 2 0 0 2 2 2 1 PDZ domain PH_11 PF15413.6 OQS07902.1 - 0.0049 17.3 0.2 0.011 16.1 0.0 1.7 2 0 0 2 2 2 1 Pleckstrin homology domain PDZ_2 PF13180.6 OQS07902.1 - 0.075 13.4 0.0 28 5.1 0.0 2.9 2 0 0 2 2 2 0 PDZ domain His_Phos_2 PF00328.22 OQS07903.1 - 5.7e-22 78.6 0.0 3.9e-09 36.3 0.0 3.3 3 0 0 3 3 3 3 Histidine phosphatase superfamily (branch 2) Gly-zipper_Omp PF13488.6 OQS07903.1 - 0.042 13.8 0.8 0.093 12.7 0.8 1.6 1 0 0 1 1 1 0 Glycine zipper COX2-transmemb PF09125.10 OQS07903.1 - 6.4 6.7 5.3 9.5 6.1 0.4 2.8 2 0 0 2 2 2 0 Cytochrome C oxidase subunit II, transmembrane RRM_1 PF00076.22 OQS07904.1 - 4.8e-49 164.1 0.0 3.2e-16 58.9 0.0 3.1 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 OQS07904.1 - 1.6e-07 31.2 0.0 7e-06 26.0 0.0 2.8 3 0 0 3 3 3 1 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.11 OQS07904.1 - 0.00015 21.8 0.0 0.0044 17.1 0.0 2.7 3 0 0 3 3 3 1 RNA binding motif RRM_7 PF16367.5 OQS07904.1 - 0.00015 21.8 0.1 0.074 13.2 0.0 3.1 3 0 0 3 3 3 1 RNA recognition motif RRM_occluded PF16842.5 OQS07904.1 - 0.023 14.5 0.0 0.39 10.6 0.0 2.3 2 0 0 2 2 2 0 Occluded RNA-recognition motif PHM7_cyt PF14703.6 OQS07904.1 - 0.041 14.1 0.0 3.1 8.0 0.0 3.3 3 1 1 4 4 4 0 Cytosolic domain of 10TM putative phosphate transporter Nup35_RRM PF05172.13 OQS07904.1 - 0.082 12.9 0.1 0.6 10.1 0.0 2.3 2 1 0 2 2 2 0 Nup53/35/40-type RNA recognition motif zf-met2 PF12907.7 OQS07905.1 - 3.2e-10 40.0 0.1 4.8e-10 39.4 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding zf-C2H2_4 PF13894.6 OQS07905.1 - 0.048 14.5 0.3 0.11 13.5 0.1 1.7 2 0 0 2 2 2 0 C2H2-type zinc finger Zn_ribbon_SprT PF17283.2 OQS07905.1 - 0.063 13.2 0.0 0.092 12.7 0.0 1.3 1 0 0 1 1 1 0 SprT-like zinc ribbon domain zf-C2H2_3rep PF18868.1 OQS07905.1 - 0.093 13.4 1.3 1.1 9.9 0.1 2.0 1 1 1 2 2 2 0 Zinc finger C2H2-type, 3 repeats UPF0542 PF15086.6 OQS07905.1 - 1.3 9.0 4.8 1.7 8.6 4.8 1.2 1 0 0 1 1 1 0 Uncharacterised protein family UPF0542 DUF3128 PF11326.8 OQS07906.1 - 2.7e-14 53.3 0.2 6.3e-14 52.1 0.2 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3128) START PF01852.19 OQS07906.1 - 0.0029 17.0 0.0 0.0052 16.2 0.0 1.4 1 0 0 1 1 1 1 START domain FYVE PF01363.21 OQS07906.1 - 0.38 10.9 14.7 1 9.6 13.5 2.4 1 1 1 2 2 2 0 FYVE zinc finger zf-C2HC5 PF06221.13 OQS07906.1 - 0.63 10.1 10.8 1.8 8.6 10.8 1.9 1 0 0 1 1 1 0 Putative zinc finger motif, C2HC5-type RCC1 PF00415.18 OQS07907.1 - 7.2e-39 132.2 8.0 2.6e-08 34.3 0.2 5.8 5 1 0 5 5 5 4 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 OQS07907.1 - 1.6e-14 53.2 13.5 0.0029 17.3 0.3 5.2 4 1 0 4 4 4 4 Regulator of chromosome condensation (RCC1) repeat LRR_6 PF13516.6 OQS07908.1 - 1.1e-10 40.7 9.0 0.058 13.5 0.0 6.9 7 0 0 7 7 7 4 Leucine Rich repeat LRR_9 PF14580.6 OQS07908.1 - 0.00012 21.6 2.6 0.003 17.1 0.1 3.1 2 1 1 3 3 3 1 Leucine-rich repeat LRR_4 PF12799.7 OQS07908.1 - 0.00029 21.2 7.0 0.024 15.1 0.8 4.5 2 1 0 3 3 3 1 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 OQS07908.1 - 0.00065 19.4 9.8 0.0045 16.7 0.3 4.5 4 1 0 4 4 4 1 Leucine rich repeat MitMem_reg PF13012.6 OQS07908.1 - 0.012 16.1 0.4 0.035 14.5 0.4 1.8 1 0 0 1 1 1 0 Maintenance of mitochondrial structure and function LRR_1 PF00560.33 OQS07908.1 - 1.6 9.6 5.5 17 6.4 0.0 4.7 6 0 0 6 6 6 0 Leucine Rich Repeat tRNA-synt_1c PF00749.21 OQS07909.1 - 3.1e-100 335.1 0.0 3.1e-100 335.1 0.0 1.5 2 0 0 2 2 2 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.18 OQS07909.1 - 2.9e-34 118.4 0.0 5.1e-34 117.6 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain WHEP-TRS PF00458.20 OQS07909.1 - 3e-19 68.9 2.7 9.3e-19 67.3 2.7 1.9 1 0 0 1 1 1 1 WHEP-TRS domain GST_C PF00043.25 OQS07909.1 - 3.2e-07 30.5 0.1 1.5e-06 28.4 0.1 2.2 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 OQS07909.1 - 0.00014 22.0 0.0 0.00075 19.6 0.0 2.2 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 OQS07909.1 - 0.083 12.9 0.2 0.27 11.3 0.2 1.9 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Menin PF05053.13 OQS07909.1 - 0.17 10.2 3.3 0.24 9.7 3.3 1.1 1 0 0 1 1 1 0 Menin DUF218 PF02698.17 OQS07911.1 - 7.4e-14 51.9 0.0 1.4e-13 51.0 0.0 1.4 1 0 0 1 1 1 1 DUF218 domain PPR_2 PF13041.6 OQS07912.1 - 3e-05 24.1 0.0 0.19 11.9 0.0 3.5 3 0 0 3 3 3 2 PPR repeat family PPR PF01535.20 OQS07912.1 - 0.0037 17.4 0.1 4.4 7.8 0.1 4.0 4 0 0 4 4 4 1 PPR repeat PPR_3 PF13812.6 OQS07912.1 - 0.046 13.8 0.1 0.71 10.0 0.1 2.8 3 0 0 3 3 3 0 Pentatricopeptide repeat domain PPR_long PF17177.4 OQS07912.1 - 0.073 12.4 1.5 1.7 8.0 0.0 3.2 2 2 0 3 3 3 0 Pentacotripeptide-repeat region of PRORP Leuk-A4-hydro_C PF09127.11 OQS07912.1 - 0.13 12.4 0.9 21 5.2 0.0 3.3 3 0 0 3 3 3 0 Leukotriene A4 hydrolase, C-terminal Peptidase_C48 PF02902.19 OQS07913.1 - 3.2e-26 92.5 0.9 6.9e-26 91.4 0.9 1.5 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain HECT PF00632.25 OQS07914.1 - 4.1e-56 190.7 0.0 6.5e-56 190.1 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) SPRY PF00622.28 OQS07914.1 - 1.7e-39 134.6 4.8 1.1e-24 86.8 0.5 2.5 2 0 0 2 2 2 2 SPRY domain MIB_HERC2 PF06701.13 OQS07914.1 - 6.7e-19 67.9 7.7 2e-18 66.4 7.7 1.9 1 0 0 1 1 1 1 Mib_herc2 PRY PF13765.6 OQS07914.1 - 0.026 14.1 0.0 0.094 12.4 0.0 2.0 1 0 0 1 1 1 0 SPRY-associated domain EF-hand_6 PF13405.6 OQS07915.1 - 3e-13 48.5 3.5 0.055 13.4 0.1 4.7 4 0 0 4 4 4 4 EF-hand domain EF-hand_1 PF00036.32 OQS07915.1 - 1.2e-12 46.4 6.6 0.00017 20.9 0.6 4.5 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 OQS07915.1 - 3e-08 34.0 7.6 4.5e-05 23.8 1.2 2.9 3 1 0 3 3 3 2 EF-hand domain pair EF-hand_8 PF13833.6 OQS07915.1 - 7.6e-06 25.7 2.1 1.7 8.6 0.3 3.5 3 0 0 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.6 OQS07915.1 - 1.9e-05 23.9 3.1 0.57 9.8 0.0 4.3 4 0 0 4 4 4 2 EF hand EF-hand_4 PF12763.7 OQS07915.1 - 0.0037 17.2 0.4 0.016 15.2 0.4 2.1 1 1 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand EamA PF00892.20 OQS07916.1 - 3.7e-24 85.4 78.2 5.6e-11 42.8 19.1 4.1 4 0 0 4 4 4 4 EamA-like transporter family TPT PF03151.16 OQS07916.1 - 2e-05 24.1 26.6 6.1e-05 22.5 2.3 3.3 4 0 0 4 4 4 2 Triose-phosphate Transporter family PPR_2 PF13041.6 OQS07917.1 - 0.052 13.7 2.0 5.2 7.3 0.0 3.3 4 0 0 4 4 4 0 PPR repeat family PPR PF01535.20 OQS07917.1 - 0.39 11.1 1.7 43 4.7 0.1 3.4 3 0 0 3 3 3 0 PPR repeat Ank_2 PF12796.7 OQS07919.1 - 7.7e-05 23.2 0.0 0.00081 19.9 0.0 2.0 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQS07919.1 - 0.038 14.6 0.1 0.93 10.2 0.0 2.9 2 1 2 4 4 4 0 Ankyrin repeats (many copies) RHD_dimer PF16179.5 OQS07919.1 - 0.072 13.1 0.0 0.1 12.6 0.0 1.3 1 0 0 1 1 1 0 Rel homology dimerisation domain Pkinase_Tyr PF07714.17 OQS07920.1 - 2.9e-23 82.5 0.0 4e-23 82.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OQS07920.1 - 1e-20 74.2 0.0 1.2e-20 74.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain PhoPQ_related PF10142.9 OQS07921.1 - 0.0017 17.1 0.1 0.0018 17.0 0.1 1.0 1 0 0 1 1 1 1 PhoPQ-activated pathogenicity-related protein DLH PF01738.18 OQS07921.1 - 0.0025 17.4 0.1 0.0028 17.2 0.1 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Hydrolase_4 PF12146.8 OQS07921.1 - 0.0061 15.8 0.1 0.0071 15.6 0.1 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 FSH1 PF03959.13 OQS07921.1 - 0.0073 16.0 0.2 0.0082 15.8 0.2 1.1 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_1 PF00561.20 OQS07921.1 - 0.018 14.7 0.1 0.022 14.4 0.1 1.1 1 0 0 1 1 1 0 alpha/beta hydrolase fold BAAT_C PF08840.11 OQS07921.1 - 0.046 13.6 0.1 0.052 13.5 0.1 1.1 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_4 PF08386.10 OQS07921.1 - 0.11 12.7 0.0 0.13 12.4 0.0 1.1 1 0 0 1 1 1 0 TAP-like protein Abhydrolase_6 PF12697.7 OQS07921.1 - 0.13 12.9 0.0 0.15 12.7 0.0 1.1 1 0 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 OQS07922.1 - 1.1e-19 71.1 0.0 1.4e-19 70.8 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 OQS07922.1 - 2.7e-10 41.2 0.1 3.6e-10 40.8 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 OQS07922.1 - 6.6e-09 35.4 0.0 8.9e-09 35.0 0.0 1.1 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Esterase PF00756.20 OQS07922.1 - 0.074 12.7 0.0 0.1 12.2 0.0 1.2 1 0 0 1 1 1 0 Putative esterase CBM-like PF14683.6 OQS07923.1 - 8.5e-35 120.1 1.5 1.2e-34 119.5 0.1 1.9 2 0 0 2 2 2 1 Polysaccharide lyase family 4, domain III RhgB_N PF09284.10 OQS07923.1 - 3.8e-25 88.9 1.0 4.5e-25 88.6 0.1 1.6 2 0 0 2 2 2 1 Rhamnogalacturonan lyase B, N-terminal fn3_3 PF14686.6 OQS07923.1 - 9.6e-17 60.5 5.2 9.6e-17 60.5 5.2 2.1 3 0 0 3 3 3 1 Polysaccharide lyase family 4, domain II CarboxypepD_reg PF13620.6 OQS07923.1 - 4e-06 27.0 6.9 7.6e-06 26.1 6.1 2.0 2 0 0 2 2 2 1 Carboxypeptidase regulatory-like domain DUF2012 PF09430.10 OQS07923.1 - 0.0064 16.6 0.0 0.016 15.3 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2012) Y_Y_Y PF07495.13 OQS07923.1 - 0.022 14.7 0.1 0.063 13.2 0.1 1.7 1 0 0 1 1 1 0 Y_Y_Y domain MoaF PF10703.9 OQS07923.1 - 0.1 12.6 0.3 0.25 11.3 0.1 1.8 2 0 0 2 2 2 0 MoaF N-terminal domain ABC_tran PF00005.27 OQS07924.1 - 0.0015 19.0 0.0 0.0018 18.8 0.0 1.1 1 0 0 1 1 1 1 ABC transporter ATP-synt_DE_N PF02823.16 OQS07925.1 - 5.7e-14 51.8 0.5 1e-13 50.9 0.1 1.7 2 0 0 2 2 2 1 ATP synthase, Delta/Epsilon chain, beta-sandwich domain DUF2544 PF11245.8 OQS07925.1 - 0.098 12.1 0.0 0.14 11.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2544) Glyco_transf_41 PF13844.6 OQS07926.1 - 2.2e-21 75.8 0.0 1.5e-14 53.3 0.0 2.2 2 0 0 2 2 2 2 Glycosyl transferase family 41 TPR_14 PF13428.6 OQS07926.1 - 9.7e-15 54.0 10.6 0.0011 19.5 0.2 7.6 3 1 4 7 7 7 2 Tetratricopeptide repeat TPR_11 PF13414.6 OQS07926.1 - 1.9e-14 53.0 6.6 0.00013 21.6 0.0 6.2 5 2 2 7 7 7 4 TPR repeat TPR_2 PF07719.17 OQS07926.1 - 4.8e-14 51.3 13.8 0.0025 17.8 0.0 7.6 8 1 0 8 8 7 4 Tetratricopeptide repeat TPR_19 PF14559.6 OQS07926.1 - 3.6e-13 49.8 10.6 0.025 15.1 0.1 5.5 4 1 1 5 5 5 4 Tetratricopeptide repeat TPR_8 PF13181.6 OQS07926.1 - 1.3e-12 46.9 11.6 0.59 10.5 0.0 7.6 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_12 PF13424.6 OQS07926.1 - 6.2e-12 45.6 14.8 0.0003 21.0 0.9 6.5 3 2 3 6 6 6 5 Tetratricopeptide repeat TPR_1 PF00515.28 OQS07926.1 - 6.6e-12 44.7 20.0 0.00023 20.8 0.0 7.6 9 0 0 9 9 7 4 Tetratricopeptide repeat TPR_16 PF13432.6 OQS07926.1 - 1.1e-11 45.1 10.4 0.0052 17.4 0.0 5.4 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_7 PF13176.6 OQS07926.1 - 5.7e-11 41.7 4.1 0.76 9.9 0.1 6.7 7 0 0 7 7 6 3 Tetratricopeptide repeat TPR_6 PF13174.6 OQS07926.1 - 4.8e-08 33.1 13.4 0.067 13.9 0.2 7.0 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_17 PF13431.6 OQS07926.1 - 1.3e-07 31.5 6.0 0.29 11.6 0.2 6.5 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_9 PF13371.6 OQS07926.1 - 5.1e-07 29.7 6.2 1 9.6 0.2 4.5 3 1 0 4 4 4 3 Tetratricopeptide repeat TPR_10 PF13374.6 OQS07926.1 - 0.00018 21.3 14.2 1 9.3 0.1 5.7 5 1 0 5 5 4 2 Tetratricopeptide repeat ANAPC3 PF12895.7 OQS07926.1 - 0.00045 20.4 4.6 0.61 10.4 0.0 4.5 4 1 1 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 Glyco_trans_1_4 PF13692.6 OQS07926.1 - 0.0037 17.7 0.0 0.014 15.8 0.0 1.9 2 0 0 2 2 2 1 Glycosyl transferases group 1 NARP1 PF12569.8 OQS07926.1 - 0.012 14.5 1.8 0.97 8.3 0.1 2.9 1 1 2 3 3 3 0 NMDA receptor-regulated protein 1 HrpB1_HrpK PF09613.10 OQS07926.1 - 0.027 14.1 2.1 1.8 8.2 0.3 3.1 3 0 0 3 3 3 0 Bacterial type III secretion protein (HrpB1_HrpK) TPR_4 PF07721.14 OQS07926.1 - 0.075 13.7 0.3 14 6.6 0.0 4.3 5 0 0 5 5 3 0 Tetratricopeptide repeat Stealth_CR2 PF11380.8 OQS07927.1 - 1.1e-24 86.7 0.1 2.5e-24 85.5 0.1 1.6 1 0 0 1 1 1 1 Stealth protein CR2, conserved region 2 Stealth_CR1 PF17101.5 OQS07927.1 - 2.7e-07 30.2 0.3 4.9e-07 29.4 0.3 1.4 1 0 0 1 1 1 1 Stealth protein CR1, conserved region 1 ABC2_membrane PF01061.24 OQS07928.1 - 5.2e-69 231.9 55.6 2.3e-35 121.9 30.8 3.1 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.27 OQS07928.1 - 1.1e-43 149.0 0.0 8.6e-21 74.9 0.0 2.5 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 OQS07928.1 - 2.4e-11 44.0 0.0 0.0018 18.1 0.0 4.3 3 1 1 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 OQS07928.1 - 1.4e-07 32.1 0.0 0.0009 19.7 0.0 2.4 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.6 OQS07928.1 - 1.7e-07 30.9 1.8 0.019 14.7 0.4 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 OQS07928.1 - 2.3e-07 30.9 0.1 0.0047 16.8 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA PF00004.29 OQS07928.1 - 8.1e-07 29.5 0.5 0.00045 20.6 0.0 3.1 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 OQS07928.1 - 6.3e-06 25.9 2.3 0.029 13.9 0.1 2.9 3 0 0 3 3 3 2 AAA domain AAA_30 PF13604.6 OQS07928.1 - 9e-06 25.5 0.1 0.028 14.1 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.6 OQS07928.1 - 1e-05 25.8 0.6 0.051 13.9 0.0 3.4 3 1 1 4 4 3 2 AAA domain Rad17 PF03215.15 OQS07928.1 - 1.4e-05 25.1 0.1 0.0011 18.9 0.0 2.5 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_23 PF13476.6 OQS07928.1 - 5.7e-05 23.7 1.7 0.28 11.6 0.1 2.4 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.6 OQS07928.1 - 8.3e-05 23.1 0.0 0.061 13.9 0.0 2.9 3 0 0 3 3 2 1 AAA domain NACHT PF05729.12 OQS07928.1 - 0.00015 21.8 0.9 0.12 12.3 0.1 2.6 2 0 0 2 2 2 2 NACHT domain AAA_33 PF13671.6 OQS07928.1 - 0.00015 22.0 0.1 0.21 11.7 0.0 2.4 2 0 0 2 2 2 2 AAA domain ABC2_membrane_3 PF12698.7 OQS07928.1 - 0.00097 18.3 16.3 0.00097 18.3 16.3 2.8 2 1 0 2 2 2 1 ABC-2 family transporter protein RNA_helicase PF00910.22 OQS07928.1 - 0.0015 18.9 0.1 0.59 10.6 0.0 3.2 3 0 0 3 3 2 1 RNA helicase AAA_5 PF07728.14 OQS07928.1 - 0.0023 17.9 1.1 0.03 14.3 0.0 2.7 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 OQS07928.1 - 0.0038 17.0 0.7 0.2 11.4 0.1 2.4 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain TsaE PF02367.17 OQS07928.1 - 0.0045 17.0 1.9 1.1 9.3 0.4 2.5 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_19 PF13245.6 OQS07928.1 - 0.0046 17.3 2.7 0.062 13.6 0.2 3.2 2 1 0 2 2 2 1 AAA domain AAA_28 PF13521.6 OQS07928.1 - 0.005 17.1 1.4 1.1 9.5 0.0 2.4 2 0 0 2 2 2 1 AAA domain ATPase_2 PF01637.18 OQS07928.1 - 0.0051 16.7 0.0 0.37 10.7 0.0 2.5 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea SMC_N PF02463.19 OQS07928.1 - 0.0077 15.7 0.1 21 4.4 0.0 4.0 4 0 0 4 4 4 0 RecF/RecN/SMC N terminal domain cobW PF02492.19 OQS07928.1 - 0.0097 15.5 2.8 1.3 8.6 0.1 2.4 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_24 PF13479.6 OQS07928.1 - 0.012 15.3 1.3 3.4 7.3 0.1 2.7 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 OQS07928.1 - 0.016 15.1 2.3 0.53 10.2 0.0 3.2 3 0 0 3 3 3 0 NTPase AAA_15 PF13175.6 OQS07928.1 - 0.019 14.7 0.0 1.1 8.9 0.0 2.9 3 0 0 3 3 3 0 AAA ATPase domain NB-ARC PF00931.22 OQS07928.1 - 0.03 13.5 0.1 7.4 5.7 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain Mg_chelatase PF01078.21 OQS07928.1 - 0.039 13.3 0.8 0.2 11.0 0.0 2.2 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_11 PF13086.6 OQS07928.1 - 0.041 13.7 0.1 0.088 12.6 0.1 1.5 1 0 0 1 1 1 0 AAA domain PduV-EutP PF10662.9 OQS07928.1 - 0.044 13.5 2.2 5.6 6.7 0.2 2.6 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation MMR_HSR1 PF01926.23 OQS07928.1 - 0.047 13.8 0.1 11 6.2 0.0 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_14 PF13173.6 OQS07928.1 - 0.056 13.5 0.1 1.9 8.5 0.0 2.6 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 OQS07928.1 - 0.06 12.6 0.6 8.7 5.6 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin DUF2399 PF09664.10 OQS07928.1 - 0.17 11.8 0.0 0.36 10.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function C-terminus (DUF2399) Viral_helicase1 PF01443.18 OQS07928.1 - 0.17 11.6 1.0 0.27 10.9 0.1 1.8 2 0 0 2 2 1 0 Viral (Superfamily 1) RNA helicase AAA_17 PF13207.6 OQS07928.1 - 0.3 11.5 1.2 2.9 8.3 0.1 2.4 2 0 0 2 2 2 0 AAA domain T2SSE PF00437.20 OQS07928.1 - 0.31 10.0 2.8 0.16 11.0 0.1 1.8 2 0 0 2 2 2 0 Type II/IV secretion system protein ATPase PF06745.13 OQS07928.1 - 0.34 10.2 1.2 10 5.4 0.1 2.4 2 0 0 2 2 2 0 KaiC NPCC PF08058.11 OQS07929.1 - 0.013 15.5 0.5 0.041 13.9 0.5 1.8 1 0 0 1 1 1 0 Nuclear pore complex component ABC2_membrane PF01061.24 OQS07930.1 - 2.4e-14 53.3 15.8 3.2e-14 52.8 15.8 1.2 1 0 0 1 1 1 1 ABC-2 type transporter 7tm_3 PF00003.22 OQS07930.1 - 0.094 12.4 14.6 0.12 12.1 14.6 1.1 1 0 0 1 1 1 0 7 transmembrane sweet-taste receptor of 3 GCPR Ank_2 PF12796.7 OQS07931.1 - 1.1e-16 61.2 3.1 4.6e-12 46.4 0.1 2.6 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OQS07931.1 - 4.1e-16 59.1 0.7 6.4e-05 23.4 0.0 4.5 3 1 2 5 5 5 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 OQS07931.1 - 1.4e-14 52.8 2.4 0.00091 19.5 0.0 4.5 4 0 0 4 4 4 3 Ankyrin repeat Ank PF00023.30 OQS07931.1 - 6.7e-13 48.4 6.5 0.00011 22.5 0.1 4.7 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.6 OQS07931.1 - 3e-12 46.5 2.0 6.5e-06 26.3 0.1 4.5 3 2 1 4 4 4 2 Ankyrin repeats (many copies) FYVE PF01363.21 OQS07931.1 - 1.4e-08 34.7 8.0 2.6e-08 33.9 8.0 1.4 1 0 0 1 1 1 1 FYVE zinc finger PDZ PF00595.24 OQS07931.1 - 0.00073 19.8 0.0 0.0022 18.3 0.0 1.8 1 0 0 1 1 1 1 PDZ domain Lipase_3 PF01764.25 OQS07932.1 - 3.2e-11 43.3 0.0 8.2e-11 42.0 0.0 1.7 1 1 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 OQS07932.1 - 0.0036 17.9 0.0 0.0089 16.7 0.0 1.7 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.13 OQS07932.1 - 0.013 15.3 0.1 0.024 14.4 0.1 1.4 1 0 0 1 1 1 0 PGAP1-like protein UPF0227 PF05728.12 OQS07932.1 - 0.025 14.5 0.0 0.051 13.5 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) DUF2974 PF11187.8 OQS07932.1 - 0.056 13.0 0.0 0.21 11.1 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2974) Hydrolase_4 PF12146.8 OQS07932.1 - 0.082 12.2 0.0 0.16 11.2 0.0 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Abhydrolase_5 PF12695.7 OQS07932.1 - 0.21 11.3 0.0 0.39 10.5 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family IBN_N PF03810.19 OQS07933.1 - 9.6e-05 22.2 1.0 0.00036 20.4 1.0 2.1 1 0 0 1 1 1 1 Importin-beta N-terminal domain Xpo1 PF08389.12 OQS07933.1 - 0.067 13.3 4.6 0.92 9.6 0.1 4.1 4 0 0 4 4 4 0 Exportin 1-like protein Carbam_trans_N PF02543.15 OQS07934.1 - 0.017 14.8 0.1 0.026 14.2 0.1 1.3 1 0 0 1 1 1 0 Carbamoyltransferase N-terminus DUF4472 PF14739.6 OQS07934.1 - 1.4 9.7 10.8 0.34 11.6 7.6 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4472) PEP-utilisers_N PF05524.13 OQS07935.1 - 0.0058 16.8 4.3 27 4.9 0.0 4.3 4 0 0 4 4 4 1 PEP-utilising enzyme, N-terminal Spc24 PF08286.11 OQS07935.1 - 0.029 14.6 7.6 0.67 10.2 0.3 2.8 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 DUF2753 PF10952.8 OQS07935.1 - 0.06 13.5 0.1 0.18 12.0 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2753) DUF724 PF05266.14 OQS07935.1 - 0.16 11.8 16.9 0.17 11.7 3.7 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF724) Terminase_6 PF03237.15 OQS07935.1 - 0.24 11.1 1.2 6.7 6.3 0.0 3.4 4 0 0 4 4 4 0 Terminase-like family ANAPC9 PF12856.7 OQS07935.1 - 0.31 11.2 2.7 21 5.3 0.0 3.1 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 9 COX14 PF14880.6 OQS07936.1 - 1.2e-06 28.2 1.5 2e-06 27.5 1.5 1.4 1 1 0 1 1 1 1 Cytochrome oxidase c assembly Keratin_assoc PF09775.9 OQS07936.1 - 0.033 13.8 0.0 0.036 13.7 0.0 1.1 1 0 0 1 1 1 0 Keratinocyte-associated protein 2 Band_7 PF01145.25 OQS07937.1 - 7.4e-25 88.0 4.7 1.1e-24 87.4 2.2 2.2 1 1 1 2 2 2 1 SPFH domain / Band 7 family ATP-synt_ab_C PF00306.27 OQS07937.1 - 0.011 16.0 0.7 0.019 15.3 0.7 1.4 1 0 0 1 1 1 0 ATP synthase alpha/beta chain, C terminal domain UAA PF08449.11 OQS07938.1 - 1.3e-40 139.5 18.8 1.5e-40 139.3 18.8 1.0 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.20 OQS07938.1 - 6.8e-12 45.7 29.5 3.6e-07 30.4 10.9 2.1 2 0 0 2 2 2 2 EamA-like transporter family TPT PF03151.16 OQS07938.1 - 1.1e-11 44.7 10.6 1.8e-11 44.0 10.6 1.2 1 0 0 1 1 1 1 Triose-phosphate Transporter family CRT-like PF08627.10 OQS07938.1 - 8.5e-08 31.5 4.4 8.5e-08 31.5 4.4 2.3 1 1 1 2 2 2 1 CRT-like, chloroquine-resistance transporter-like Phage_holin_2_4 PF16082.5 OQS07938.1 - 0.012 15.3 0.0 0.031 14.0 0.0 1.7 1 0 0 1 1 1 0 Bacteriophage holin family, superfamily II-like LAT PF15234.6 OQS07939.1 - 0.0087 15.8 2.0 0.02 14.7 2.0 1.5 1 0 0 1 1 1 1 Linker for activation of T-cells GPS2_interact PF15784.5 OQS07939.1 - 0.045 14.2 0.6 0.15 12.5 0.6 1.9 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain Syntaxin-6_N PF09177.11 OQS07939.1 - 0.2 12.2 5.8 0.14 12.7 2.8 2.3 2 1 1 3 3 3 0 Syntaxin 6, N-terminal CCDC-167 PF15188.6 OQS07939.1 - 5.3 7.5 7.5 0.36 11.2 1.6 2.1 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 EamA PF00892.20 OQS07940.1 - 1.7e-06 28.3 16.6 1.7e-06 28.3 16.6 2.1 2 0 0 2 2 2 1 EamA-like transporter family Gly-zipper_YMGG PF13441.6 OQS07940.1 - 0.051 13.3 5.3 0.11 12.2 5.3 1.5 1 1 0 1 1 1 0 YMGG-like Gly-zipper RseC_MucC PF04246.12 OQS07940.1 - 5.3 7.0 9.1 1.9 8.5 0.6 3.2 2 1 1 3 3 3 0 Positive regulator of sigma(E), RseC/MucC COG5 PF10392.9 OQS07941.1 - 3.2e-14 53.2 3.8 4.4e-13 49.6 2.1 2.9 2 0 0 2 2 2 1 Golgi transport complex subunit 5 Med21 PF11221.8 OQS07941.1 - 3.1e-07 30.8 18.7 2.1e-05 24.8 3.0 3.9 2 1 2 4 4 4 2 Subunit 21 of Mediator complex MDM10 PF12519.8 OQS07941.1 - 0.059 12.2 0.3 0.097 11.5 0.3 1.3 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 LPP PF04728.13 OQS07941.1 - 0.097 13.1 2.2 0.86 10.0 0.2 3.3 3 0 0 3 3 3 0 Lipoprotein leucine-zipper Med9 PF07544.13 OQS07941.1 - 0.12 12.4 3.5 0.56 10.3 0.6 2.7 2 0 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 DUF948 PF06103.11 OQS07941.1 - 0.15 12.3 0.6 0.92 9.8 0.6 2.4 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) TolA_bind_tri PF16331.5 OQS07941.1 - 0.46 10.6 4.1 0.55 10.3 1.7 2.5 2 0 0 2 2 2 0 TolA binding protein trimerisation NPV_P10 PF05531.12 OQS07941.1 - 0.64 10.5 6.8 6.4 7.3 2.5 4.1 5 0 0 5 5 5 0 Nucleopolyhedrovirus P10 protein LXG PF04740.12 OQS07941.1 - 1.7 8.3 9.3 0.11 12.2 2.8 2.3 4 0 0 4 4 4 0 LXG domain of WXG superfamily DUF4520 PF15016.6 OQS07942.1 - 1.6e-11 44.2 0.2 1.4e-10 41.1 0.2 2.3 1 1 0 1 1 1 1 Domain of unknown function (DUF4520) YchF-GTPase_C PF06071.13 OQS07943.1 - 2.9e-39 133.1 0.3 7.9e-39 131.7 0.3 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.23 OQS07943.1 - 2e-19 69.7 0.0 4.5e-19 68.6 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 OQS07943.1 - 1.2e-06 28.1 0.0 3.2e-06 26.8 0.0 1.7 1 0 0 1 1 1 1 Ferrous iron transport protein B TGS PF02824.21 OQS07943.1 - 0.0047 16.9 0.0 0.009 16.0 0.0 1.4 1 0 0 1 1 1 1 TGS domain AAA_18 PF13238.6 OQS07943.1 - 0.068 13.7 0.0 0.16 12.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 OQS07943.1 - 0.1 13.1 0.0 0.56 10.7 0.0 1.9 2 0 0 2 2 2 0 ABC transporter DUF2373 PF10180.9 OQS07944.1 - 2.6e-18 65.6 0.6 6e-18 64.4 0.4 1.7 2 0 0 2 2 2 1 Uncharacterised conserved protein (DUF2373) DUF4524 PF15025.6 OQS07944.1 - 5.1e-10 39.3 0.0 7.3e-10 38.8 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4524) FAT PF02259.23 OQS07945.1 - 1.8e-07 30.7 4.7 1.4e-05 24.5 0.0 3.1 3 0 0 3 3 3 2 FAT domain TPR_12 PF13424.6 OQS07945.1 - 0.0091 16.3 0.3 0.035 14.4 0.3 2.0 1 0 0 1 1 1 1 Tetratricopeptide repeat DUF3385 PF11865.8 OQS07945.1 - 0.021 14.7 0.2 0.29 11.0 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3385) TPR_7 PF13176.6 OQS07945.1 - 0.036 14.1 0.1 0.2 11.7 0.1 2.3 1 0 0 1 1 1 0 Tetratricopeptide repeat DUF4423 PF14394.6 OQS07945.1 - 0.091 12.5 0.1 0.27 10.9 0.1 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4423) TPR_2 PF07719.17 OQS07945.1 - 0.24 11.6 0.8 1.8 8.8 0.1 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat PI3_PI4_kinase PF00454.27 OQS07946.1 - 2.1e-52 178.4 0.0 3.8e-52 177.6 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.20 OQS07946.1 - 1.6e-17 63.0 0.1 4.5e-17 61.6 0.0 1.9 2 0 0 2 2 2 1 FATC domain FAT PF02259.23 OQS07946.1 - 6.6e-09 35.4 1.5 6.6e-09 35.4 1.5 3.3 3 2 0 3 3 3 1 FAT domain Utp13 PF08625.11 OQS07946.1 - 0.044 13.7 0.9 0.12 12.3 0.4 1.9 2 0 0 2 2 2 0 Utp13 specific WD40 associated domain PGP_phosphatase PF09419.10 OQS07947.1 - 1.4e-23 83.4 0.0 1.6e-23 83.1 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial PGP phosphatase Hydrolase_like PF13242.6 OQS07947.1 - 1.5e-07 31.4 0.0 2.8e-07 30.5 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like HAD_2 PF13419.6 OQS07947.1 - 0.0001 22.5 0.0 0.00013 22.1 0.0 1.3 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 OQS07947.1 - 0.00011 22.6 0.0 0.00014 22.2 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase FrhB_FdhB_C PF04432.13 OQS07947.1 - 0.053 13.3 0.0 0.072 12.9 0.0 1.3 1 0 0 1 1 1 0 Coenzyme F420 hydrogenase/dehydrogenase, beta subunit C terminus PepX_C PF08530.10 OQS07948.1 - 2.2e-21 76.9 0.0 2.5e-21 76.6 0.0 1.0 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain PepX_C PF08530.10 OQS07949.1 - 3.9e-11 43.3 0.0 6.9e-11 42.5 0.0 1.4 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain Peptidase_S15 PF02129.18 OQS07949.1 - 1.7e-06 27.8 0.0 2.6e-06 27.2 0.0 1.3 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) HEPN_Apea PF18739.1 OQS07949.1 - 0.11 12.9 0.3 0.29 11.6 0.3 1.7 1 0 0 1 1 1 0 Apea-like HEPN Peroxidase_2 PF01328.17 OQS07951.1 - 3.4e-44 151.6 0.1 6.5e-24 85.5 0.0 2.6 3 0 0 3 3 3 2 Peroxidase, family 2 DUF3886 PF13025.6 OQS07951.1 - 2.8 8.2 9.7 24 5.2 5.2 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3886) Nup35_RRM PF05172.13 OQS07952.1 - 4.1e-15 55.6 0.1 2.5e-14 53.1 0.1 2.0 1 1 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Nup35_RRM_2 PF14605.6 OQS07952.1 - 1.5e-10 40.9 0.0 3.8e-10 39.6 0.1 1.7 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif LRR_4 PF12799.7 OQS07953.1 - 1.3e-09 38.2 3.6 8.5e-07 29.2 0.8 3.1 1 1 3 4 4 4 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 OQS07953.1 - 2.7e-06 27.0 6.3 8.4e-06 25.5 4.6 2.7 2 1 0 2 2 2 1 Leucine rich repeat LRR_9 PF14580.6 OQS07953.1 - 3.9e-05 23.2 1.6 6.8e-05 22.4 1.6 1.4 1 0 0 1 1 1 1 Leucine-rich repeat LRR_6 PF13516.6 OQS07953.1 - 0.0002 21.2 1.4 0.29 11.3 0.0 4.5 4 0 0 4 4 4 1 Leucine Rich repeat LRR_1 PF00560.33 OQS07953.1 - 0.5 11.1 4.6 9.5 7.2 0.3 4.1 2 2 0 2 2 2 0 Leucine Rich Repeat Histidinol_dh PF00815.20 OQS07953.1 - 6.8 5.6 7.4 9.3 5.1 7.4 1.2 1 0 0 1 1 1 0 Histidinol dehydrogenase Voltage_CLC PF00654.20 OQS07954.1 - 8.8e-94 314.6 8.5 8.8e-94 314.6 8.5 2.0 1 1 1 2 2 2 1 Voltage gated chloride channel CBS PF00571.28 OQS07954.1 - 1.6e-05 25.2 0.0 0.00037 20.9 0.0 2.5 2 0 0 2 2 2 1 CBS domain DUF2516 PF10724.9 OQS07954.1 - 2.6 8.4 6.8 0.23 11.7 0.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2516) TatD_DNase PF01026.21 OQS07955.1 - 1e-45 156.1 0.0 2.6e-44 151.5 0.0 2.0 1 1 0 1 1 1 1 TatD related DNase Coa1 PF08695.10 OQS07956.1 - 4.6e-10 39.3 0.0 1e-06 28.5 0.0 2.4 2 1 0 2 2 2 2 Cytochrome oxidase complex assembly protein 1 HU-CCDC81_euk_2 PF18289.1 OQS07957.1 - 2.3e-14 53.3 0.5 6.7e-13 48.6 0.0 2.4 2 0 0 2 2 2 1 CCDC81 eukaryotic HU domain 2 HU-CCDC81_euk_1 PF14908.6 OQS07957.1 - 2.4e-06 27.6 0.9 2.5e-05 24.4 0.9 2.6 1 1 0 1 1 1 1 CCDC81 eukaryotic HU domain 1 DUF3141 PF11339.8 OQS07957.1 - 0.01 14.3 1.1 0.015 13.8 1.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3141) Nuc_H_symport PF03825.16 OQS07957.1 - 0.2 10.6 0.0 0.37 9.7 0.0 1.3 1 0 0 1 1 1 0 Nucleoside H+ symporter Bac_DNA_binding PF00216.21 OQS07957.1 - 0.63 10.3 5.1 0.7 10.1 0.1 3.5 4 1 0 4 4 4 0 Bacterial DNA-binding protein Kinesin PF00225.23 OQS07958.1 - 1.4e-104 349.7 0.6 1.4e-104 349.7 0.6 2.3 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 OQS07958.1 - 2.5e-21 76.2 0.0 2.2e-20 73.1 0.0 2.8 1 0 0 1 1 1 1 Microtubule binding MIP-T3 PF10243.9 OQS07958.1 - 3.2e-21 75.4 0.2 3.2e-21 75.4 0.2 2.9 3 0 0 3 3 3 1 Microtubule-binding protein MIP-T3 CH-like domain F5_F8_type_C PF00754.25 OQS07958.1 - 1.7e-18 66.9 0.0 1.3e-10 41.5 0.0 3.1 2 0 0 2 2 2 2 F5/8 type C domain AAA_22 PF13401.6 OQS07958.1 - 2.6 8.3 5.7 2 8.7 0.0 3.8 4 1 0 4 4 4 0 AAA domain GAS PF13851.6 OQS07958.1 - 7.4 5.9 106.5 0.017 14.5 20.0 6.3 3 1 2 6 6 6 0 Growth-arrest specific micro-tubule binding MARVEL PF01284.23 OQS07959.1 - 0.048 13.7 28.3 0.11 12.5 10.5 2.4 2 0 0 2 2 2 0 Membrane-associating domain OppC_N PF12911.7 OQS07959.1 - 0.15 12.0 4.4 36 4.4 0.0 3.9 3 0 0 3 3 3 0 N-terminal TM domain of oligopeptide transport permease C DUF4419 PF14388.6 OQS07959.1 - 0.31 10.4 1.7 0.5 9.7 1.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4419) Ndc1_Nup PF09531.10 OQS07961.1 - 4.1 6.0 15.9 7.4 5.1 15.9 1.4 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup C2 PF00168.30 OQS07962.1 - 3.7e-09 36.8 0.0 6.2e-09 36.1 0.0 1.4 1 0 0 1 1 1 1 C2 domain AAA PF00004.29 OQS07963.1 - 3.6e-93 308.9 0.0 2.4e-49 167.2 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 OQS07963.1 - 3.7e-26 90.7 0.1 3.8e-12 45.8 0.0 2.7 2 0 0 2 2 2 2 AAA+ lid domain RuvB_N PF05496.12 OQS07963.1 - 2.4e-16 59.9 0.0 1.2e-07 31.6 0.0 2.8 3 0 0 3 3 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 OQS07963.1 - 3.9e-13 50.2 0.7 0.002 18.6 0.0 5.4 3 2 2 5 5 5 2 AAA ATPase domain AAA_5 PF07728.14 OQS07963.1 - 7e-12 45.5 3.7 0.001 19.1 0.0 5.2 3 3 0 3 3 3 2 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 OQS07963.1 - 9.8e-12 45.3 0.0 8.2e-05 22.8 0.0 2.9 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_33 PF13671.6 OQS07963.1 - 9.2e-11 42.1 0.0 0.00019 21.6 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.6 OQS07963.1 - 3.2e-10 40.4 0.7 0.02 15.1 0.0 4.4 2 2 1 3 3 3 2 AAA domain TIP49 PF06068.13 OQS07963.1 - 1.8e-08 34.0 0.3 0.004 16.4 0.1 2.7 2 1 1 3 3 3 2 TIP49 P-loop domain IstB_IS21 PF01695.17 OQS07963.1 - 5.9e-08 32.6 0.0 0.011 15.4 0.0 2.6 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_18 PF13238.6 OQS07963.1 - 6.1e-08 33.3 0.1 0.014 15.9 0.0 3.1 3 0 0 3 3 2 2 AAA domain Mg_chelatase PF01078.21 OQS07963.1 - 7e-08 32.1 1.6 0.0059 16.0 0.2 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_14 PF13173.6 OQS07963.1 - 7.2e-08 32.5 0.0 0.006 16.6 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.6 OQS07963.1 - 8.8e-08 32.0 0.1 0.37 10.3 0.0 4.1 4 0 0 4 4 4 2 AAA domain RNA_helicase PF00910.22 OQS07963.1 - 2.9e-07 30.8 0.0 0.019 15.4 0.0 2.6 2 0 0 2 2 2 2 RNA helicase AAA_28 PF13521.6 OQS07963.1 - 3.9e-07 30.5 0.0 0.035 14.4 0.0 2.6 2 0 0 2 2 2 2 AAA domain NACHT PF05729.12 OQS07963.1 - 1.5e-06 28.2 3.0 0.029 14.3 0.0 3.5 4 0 0 4 4 2 2 NACHT domain ABC_tran PF00005.27 OQS07963.1 - 1.7e-06 28.6 0.9 0.072 13.6 0.0 3.5 3 1 1 4 4 3 2 ABC transporter TsaE PF02367.17 OQS07963.1 - 2.4e-06 27.6 0.0 0.022 14.8 0.0 2.3 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_24 PF13479.6 OQS07963.1 - 4.1e-06 26.7 0.1 0.12 12.1 0.1 2.9 3 0 0 3 3 2 2 AAA domain Sigma54_activat PF00158.26 OQS07963.1 - 1.2e-05 25.1 0.1 0.15 11.8 0.0 3.2 4 0 0 4 4 3 2 Sigma-54 interaction domain Parvo_NS1 PF01057.17 OQS07963.1 - 1.2e-05 24.5 0.3 0.077 12.1 0.1 2.3 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 Zeta_toxin PF06414.12 OQS07963.1 - 3.3e-05 23.3 0.3 0.062 12.6 0.0 2.7 2 0 0 2 2 2 2 Zeta toxin NB-ARC PF00931.22 OQS07963.1 - 4.8e-05 22.7 0.4 0.18 10.9 0.0 3.2 3 0 0 3 3 3 2 NB-ARC domain Nucleolin_bd PF16725.5 OQS07963.1 - 8.4e-05 22.2 0.1 0.00031 20.3 0.0 2.0 2 0 0 2 2 1 1 Nucleolin binding domain AAA_3 PF07726.11 OQS07963.1 - 0.0001 22.2 0.0 0.63 9.9 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) Sigma54_activ_2 PF14532.6 OQS07963.1 - 0.00017 21.8 0.0 0.49 10.5 0.0 3.1 2 1 1 3 3 3 1 Sigma-54 interaction domain Vps4_C PF09336.10 OQS07963.1 - 0.00017 21.5 0.2 0.34 10.9 0.0 3.0 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain AAA_7 PF12775.7 OQS07963.1 - 0.00029 20.4 0.2 0.94 9.0 0.0 2.8 2 1 0 2 2 2 2 P-loop containing dynein motor region ATPase_2 PF01637.18 OQS07963.1 - 0.00031 20.7 0.0 0.075 12.9 0.0 3.3 2 1 1 3 3 3 1 ATPase domain predominantly from Archaea Rad17 PF03215.15 OQS07963.1 - 0.00039 20.4 0.3 0.075 12.9 0.0 3.1 3 1 1 4 4 3 1 Rad17 P-loop domain AAA_17 PF13207.6 OQS07963.1 - 0.00048 20.6 0.0 0.27 11.7 0.0 3.1 2 0 0 2 2 2 1 AAA domain ATPase PF06745.13 OQS07963.1 - 0.00081 18.8 0.3 1.6 8.0 0.0 2.7 2 1 0 3 3 3 2 KaiC Viral_helicase1 PF01443.18 OQS07963.1 - 0.0011 18.8 0.0 0.39 10.4 0.0 2.6 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase CPT PF07931.12 OQS07963.1 - 0.0012 18.8 0.0 0.14 12.0 0.0 2.4 2 0 0 2 2 2 1 Chloramphenicol phosphotransferase-like protein TniB PF05621.11 OQS07963.1 - 0.0028 17.1 0.0 4.1 6.8 0.0 3.1 2 1 1 3 3 3 0 Bacterial TniB protein DUF815 PF05673.13 OQS07963.1 - 0.0048 16.1 0.0 0.31 10.2 0.0 2.6 2 1 0 2 2 2 1 Protein of unknown function (DUF815) PhoH PF02562.16 OQS07963.1 - 0.0052 16.3 1.6 2.4 7.5 0.1 2.7 3 0 0 3 3 2 1 PhoH-like protein DUF2075 PF09848.9 OQS07963.1 - 0.0063 15.8 0.8 0.91 8.7 0.0 3.0 3 0 0 3 3 3 1 Uncharacterized conserved protein (DUF2075) AAA_19 PF13245.6 OQS07963.1 - 0.0099 16.2 1.1 8.5 6.7 0.3 2.9 2 1 0 3 3 2 0 AAA domain ATP-synt_ab PF00006.25 OQS07963.1 - 0.01 15.5 0.0 0.54 9.9 0.0 2.4 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_11 PF13086.6 OQS07963.1 - 0.011 15.5 8.9 0.61 9.8 0.0 3.6 4 0 0 4 4 3 0 AAA domain AAA_30 PF13604.6 OQS07963.1 - 0.013 15.3 1.2 2 8.1 0.1 2.6 2 0 0 2 2 2 0 AAA domain Hydin_ADK PF17213.3 OQS07963.1 - 0.016 15.5 5.0 0.47 10.7 0.0 3.5 3 0 0 3 3 3 0 Hydin Adenylate kinase-like domain Bac_DnaA PF00308.18 OQS07963.1 - 0.022 14.6 0.0 2.1 8.1 0.0 2.6 2 0 0 2 2 2 0 Bacterial dnaA protein AFG1_ATPase PF03969.16 OQS07963.1 - 0.023 13.6 0.1 0.72 8.7 0.0 2.5 2 0 0 2 2 2 0 AFG1-like ATPase PduV-EutP PF10662.9 OQS07963.1 - 0.024 14.4 0.0 3.1 7.5 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation NTPase_1 PF03266.15 OQS07963.1 - 0.042 13.8 0.8 11 5.8 0.0 3.3 3 0 0 3 3 3 0 NTPase MMR_HSR1 PF01926.23 OQS07963.1 - 0.052 13.6 0.2 8 6.6 0.0 2.9 2 0 0 2 2 2 0 50S ribosome-binding GTPase IPT PF01745.16 OQS07963.1 - 0.052 12.9 0.1 4.4 6.6 0.0 2.5 2 0 0 2 2 2 0 Isopentenyl transferase tRNA_bind_2 PF13725.6 OQS07963.1 - 0.06 13.0 3.5 0.13 11.9 3.5 1.5 1 0 0 1 1 1 0 Possible tRNA binding domain Cytidylate_kin2 PF13189.6 OQS07963.1 - 0.072 13.2 0.3 4.2 7.5 0.0 2.8 3 0 0 3 3 2 0 Cytidylate kinase-like family DAP3 PF10236.9 OQS07963.1 - 0.097 11.8 0.0 11 5.1 0.0 2.6 3 0 0 3 3 2 0 Mitochondrial ribosomal death-associated protein 3 AAA_29 PF13555.6 OQS07963.1 - 0.12 12.1 0.0 15 5.5 0.0 2.4 2 0 0 2 2 2 0 P-loop containing region of AAA domain Cytidylate_kin PF02224.18 OQS07963.1 - 0.14 11.9 3.1 9.7 5.9 0.0 3.2 3 0 0 3 3 3 0 Cytidylate kinase FeoB_N PF02421.18 OQS07963.1 - 0.17 11.4 0.3 12 5.4 0.0 2.5 2 0 0 2 2 2 0 Ferrous iron transport protein B cobW PF02492.19 OQS07963.1 - 0.37 10.4 2.6 22 4.6 0.0 3.2 3 1 1 4 4 3 0 CobW/HypB/UreG, nucleotide-binding domain AAA_23 PF13476.6 OQS07963.1 - 0.54 10.7 7.5 15 6.0 0.0 3.4 3 0 0 3 3 3 0 AAA domain SKI PF01202.22 OQS07963.1 - 0.66 10.1 3.2 2.1 8.4 0.0 2.8 3 0 0 3 3 2 0 Shikimate kinase CRISPR_assoc PF08798.11 OQS07964.1 - 0.0021 18.2 3.0 0.0022 18.1 3.0 1.1 1 0 0 1 1 1 1 CRISPR associated protein Yop-YscD_ppl PF16693.5 OQS07964.1 - 0.017 14.6 0.7 0.02 14.3 0.7 1.2 1 0 0 1 1 1 0 Inner membrane component of T3SS, periplasmic domain DUF2229 PF09989.9 OQS07964.1 - 0.045 13.4 1.3 0.052 13.2 1.3 1.3 1 0 0 1 1 1 0 CoA enzyme activase uncharacterised domain (DUF2229) PS-DH PF14765.6 OQS07964.1 - 0.13 11.5 0.9 0.15 11.2 0.9 1.1 1 0 0 1 1 1 0 Polyketide synthase dehydratase PCI PF01399.27 OQS07965.1 - 3.3e-13 50.1 0.8 9.5e-12 45.4 0.2 2.8 2 0 0 2 2 2 1 PCI domain eIF3m_C_helix PF18005.1 OQS07965.1 - 0.00017 21.2 0.0 0.00049 19.7 0.0 1.9 1 0 0 1 1 1 1 eIF3 subunit M, C-terminal helix Tctex-1 PF03645.13 OQS07966.1 - 1.1e-18 67.3 1.1 4e-18 65.5 0.0 2.6 2 0 0 2 2 2 1 Tctex-1 family CH_2 PF06294.11 OQS07966.1 - 9.4e-15 54.5 0.0 4e-14 52.5 0.0 2.2 1 0 0 1 1 1 1 CH-like domain in sperm protein CH PF00307.31 OQS07966.1 - 0.0041 17.3 0.2 0.034 14.3 0.0 2.7 2 0 0 2 2 2 1 Calponin homology (CH) domain Myb_DNA-binding PF00249.31 OQS07967.1 - 7.4e-09 35.7 0.5 1.7e-08 34.5 0.5 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OQS07967.1 - 8.9e-09 35.5 1.4 4.5e-08 33.2 0.6 2.3 2 0 0 2 2 2 1 Myb-like DNA-binding domain Rap1_C PF11626.8 OQS07967.1 - 0.092 12.8 0.0 0.2 11.8 0.0 1.6 1 0 0 1 1 1 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain Cir_N PF10197.9 OQS07968.1 - 0.0017 18.5 5.2 0.0017 18.5 5.2 3.5 2 1 1 3 3 3 1 N-terminal domain of CBF1 interacting co-repressor CIR Pro_isomerase PF00160.21 OQS07969.1 - 2e-51 174.4 1.0 2.4e-51 174.2 0.1 1.6 2 0 0 2 2 2 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD FKBP_C PF00254.28 OQS07969.1 - 5.4e-28 97.2 0.0 1.4e-27 95.8 0.0 1.7 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase TPR_2 PF07719.17 OQS07969.1 - 2.3e-08 33.5 8.1 0.0012 18.8 0.1 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.6 OQS07969.1 - 1.3e-07 31.3 2.2 0.00031 20.7 0.0 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.28 OQS07969.1 - 0.0019 17.9 7.4 0.0081 15.9 0.1 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 OQS07969.1 - 0.0028 18.1 3.7 0.0081 16.7 3.0 2.1 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.6 OQS07969.1 - 0.0042 17.7 2.1 0.0042 17.7 2.1 2.1 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.6 OQS07969.1 - 0.0067 16.1 2.5 3 7.6 0.1 3.3 2 1 1 3 3 3 2 TPR repeat TPR_6 PF13174.6 OQS07969.1 - 0.13 12.9 2.8 5 8.0 0.1 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat Raptor_N PF14538.6 OQS07969.1 - 0.2 11.6 0.5 1 9.3 0.0 2.3 3 1 1 4 4 4 0 Raptor N-terminal CASPase like domain FRB_dom PF08771.11 OQS07969.1 - 0.37 11.2 2.5 3.9 8.0 1.4 2.4 2 0 0 2 2 2 0 FKBP12-rapamycin binding domain CWC25 PF12542.8 OQS07969.1 - 5 8.1 8.3 12 6.8 7.8 2.0 1 1 0 1 1 1 0 Pre-mRNA splicing factor LRR_6 PF13516.6 OQS07970.1 - 8.4e-12 44.1 8.5 0.0095 15.9 0.0 5.0 5 0 0 5 5 5 4 Leucine Rich repeat LRR_8 PF13855.6 OQS07970.1 - 4.4e-08 32.8 1.1 0.63 9.8 0.0 5.4 2 1 3 5 5 5 4 Leucine rich repeat LRR_4 PF12799.7 OQS07970.1 - 0.00012 22.3 0.2 0.16 12.4 0.4 4.4 4 2 1 5 5 5 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 OQS07970.1 - 0.0012 19.1 0.6 2.4 9.0 0.0 4.1 4 0 0 4 4 4 1 Leucine Rich Repeat Peptidase_M76 PF09768.9 OQS07971.1 - 8.5e-29 100.5 3.0 9.7e-29 100.3 3.0 1.0 1 0 0 1 1 1 1 Peptidase M76 family SprT-like PF10263.9 OQS07971.1 - 0.002 18.0 0.7 0.0029 17.5 0.2 1.8 2 1 0 2 2 2 1 SprT-like family ABC_tran PF00005.27 OQS07972.1 - 3.1e-32 112.0 0.0 6.9e-32 110.8 0.0 1.6 2 0 0 2 2 2 1 ABC transporter SMC_N PF02463.19 OQS07972.1 - 5.5e-07 29.2 0.1 0.00018 21.1 0.0 2.2 1 1 1 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 OQS07972.1 - 0.0024 17.7 0.1 0.82 9.4 0.3 2.2 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system MMR_HSR1 PF01926.23 OQS07972.1 - 0.0087 16.1 0.1 0.021 14.9 0.1 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF815 PF05673.13 OQS07972.1 - 0.0093 15.2 0.0 0.019 14.1 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_29 PF13555.6 OQS07972.1 - 0.032 14.0 0.0 0.089 12.5 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF87 PF01935.17 OQS07972.1 - 0.037 14.1 0.2 0.086 12.9 0.2 1.5 1 0 0 1 1 1 0 Helicase HerA, central domain DivIC PF04977.15 OQS07972.1 - 0.057 13.2 0.6 0.12 12.1 0.6 1.5 1 0 0 1 1 1 0 Septum formation initiator JIP_LZII PF16471.5 OQS07972.1 - 0.092 12.9 1.0 0.18 12.0 1.0 1.5 1 0 0 1 1 1 0 JNK-interacting protein leucine zipper II bZIP_1 PF00170.21 OQS07972.1 - 0.11 12.6 0.4 0.2 11.8 0.4 1.4 1 0 0 1 1 1 0 bZIP transcription factor RsgA_GTPase PF03193.16 OQS07972.1 - 0.12 12.3 0.0 0.23 11.4 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase AAA_5 PF07728.14 OQS07972.1 - 0.15 12.1 0.3 5 7.1 0.0 2.6 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) Med21 PF11221.8 OQS07972.1 - 0.72 10.1 2.6 1 9.6 1.8 1.7 1 1 0 1 1 1 0 Subunit 21 of Mediator complex ZapB PF06005.12 OQS07972.1 - 2 8.9 4.9 0.76 10.3 2.0 1.7 2 0 0 2 2 2 0 Cell division protein ZapB ADK PF00406.22 OQS07973.1 - 1.4e-71 239.5 0.0 2.8e-45 154.1 0.0 3.3 3 0 0 3 3 3 3 Adenylate kinase AAA_17 PF13207.6 OQS07973.1 - 1.3e-33 116.3 0.4 3.1e-23 82.7 0.0 3.2 3 0 0 3 3 3 2 AAA domain Hydin_ADK PF17213.3 OQS07973.1 - 1.5e-10 41.7 0.7 0.0027 18.0 0.0 3.3 2 1 1 3 3 3 2 Hydin Adenylate kinase-like domain AAA_18 PF13238.6 OQS07973.1 - 8.4e-09 36.1 0.1 2.6e-05 24.8 0.0 3.1 3 0 0 3 3 3 2 AAA domain AAA_33 PF13671.6 OQS07973.1 - 2.3e-05 24.6 0.1 0.002 18.3 0.0 3.5 3 2 0 3 3 3 1 AAA domain ADK_lid PF05191.14 OQS07973.1 - 0.00021 21.2 0.2 1.1 9.3 0.0 3.4 3 0 0 3 3 3 2 Adenylate kinase, active site lid Cytidylate_kin PF02224.18 OQS07973.1 - 0.024 14.4 0.0 0.045 13.5 0.0 1.4 1 0 0 1 1 1 0 Cytidylate kinase Limkain-b1 PF11608.8 OQS07973.1 - 0.035 14.2 0.1 1.3 9.2 0.0 2.6 2 0 0 2 2 2 0 Limkain b1 DUF4821 PF16092.5 OQS07973.1 - 0.069 12.8 1.0 0.25 10.9 0.4 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF4821) UPF0193 PF05250.11 OQS07974.1 - 9.6e-06 25.5 2.8 2e-05 24.5 2.8 1.5 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0193) Baculo_PEP_C PF04513.12 OQS07974.1 - 0.1 12.6 0.4 0.49 10.4 0.8 1.8 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus YlbD_coat PF14071.6 OQS07974.1 - 0.2 11.9 2.9 0.31 11.3 0.9 2.0 2 0 0 2 2 2 0 Putative coat protein Csm1_N PF18504.1 OQS07974.1 - 0.36 11.2 3.8 0.27 11.6 0.3 2.3 2 0 0 2 2 2 0 Csm1 N-terminal domain adh_short PF00106.25 OQS07975.1 - 5.6e-10 39.0 0.0 9.4e-10 38.3 0.0 1.4 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OQS07975.1 - 2.1e-07 30.7 0.0 2.8e-07 30.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Phage_TAC_9 PF10876.8 OQS07975.1 - 0.0049 17.0 0.1 0.037 14.1 0.1 2.0 2 0 0 2 2 2 1 Phage tail assemb.y chaperone protein, TAC PP2C PF00481.21 OQS07976.1 - 4.3e-36 124.9 0.0 9e-36 123.8 0.0 1.5 1 0 0 1 1 1 1 Protein phosphatase 2C cNMP_binding PF00027.29 OQS07976.1 - 5.1e-34 116.2 0.0 1.6e-15 57.0 0.0 2.5 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain PP2C_2 PF13672.6 OQS07976.1 - 0.0011 18.7 0.0 0.0056 16.3 0.0 2.2 1 1 0 1 1 1 1 Protein phosphatase 2C SUIM_assoc PF16619.5 OQS07976.1 - 0.34 11.0 1.5 2 8.5 0.0 2.6 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 DUF5523 PF17661.1 OQS07977.1 - 0.0018 18.0 6.4 0.0022 17.7 6.4 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF5523) YL1 PF05764.13 OQS07977.1 - 0.0095 16.1 7.2 0.01 16.0 7.2 1.1 1 0 0 1 1 1 1 YL1 nuclear protein Cnd2 PF05786.14 OQS07977.1 - 0.012 14.4 6.3 0.014 14.1 6.3 1.1 1 0 0 1 1 1 0 Condensin complex subunit 2 MMU163 PF17119.5 OQS07977.1 - 0.03 13.5 1.5 0.034 13.3 1.5 1.0 1 0 0 1 1 1 0 Mitochondrial protein up-regulated during meiosis Pkinase_fungal PF17667.1 OQS07977.1 - 0.045 12.5 0.1 0.054 12.3 0.1 1.0 1 0 0 1 1 1 0 Fungal protein kinase Zip PF02535.22 OQS07977.1 - 0.055 12.7 0.3 0.059 12.6 0.3 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter DUF4637 PF15470.6 OQS07977.1 - 0.059 13.1 3.8 0.068 12.9 3.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) Ureide_permease PF07168.11 OQS07977.1 - 0.064 12.0 0.9 0.074 11.8 0.9 1.0 1 0 0 1 1 1 0 Ureide permease Folliculin PF11704.8 OQS07977.1 - 0.1 12.5 0.8 0.13 12.1 0.8 1.1 1 0 0 1 1 1 0 Vesicle coat protein involved in Golgi to plasma membrane transport FAM176 PF14851.6 OQS07977.1 - 0.14 11.8 2.9 0.17 11.5 2.9 1.3 1 0 0 1 1 1 0 FAM176 family DUF4611 PF15387.6 OQS07977.1 - 0.28 11.4 8.1 0.57 10.4 8.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) CDC45 PF02724.14 OQS07977.1 - 0.43 8.8 8.1 0.5 8.6 8.1 1.1 1 0 0 1 1 1 0 CDC45-like protein Pox_Ag35 PF03286.14 OQS07977.1 - 0.45 10.3 7.7 0.53 10.0 7.7 1.1 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Connexin PF00029.19 OQS07977.1 - 0.46 10.2 1.3 0.51 10.1 1.3 1.1 1 0 0 1 1 1 0 Connexin Retinal PF15449.6 OQS07977.1 - 0.49 8.1 4.8 0.56 7.9 4.8 1.0 1 0 0 1 1 1 0 Retinal protein GOLD_2 PF13897.6 OQS07977.1 - 0.73 10.3 4.0 1 9.9 4.0 1.3 1 0 0 1 1 1 0 Golgi-dynamics membrane-trafficking Pox_RNA_Pol_19 PF05320.12 OQS07977.1 - 1.6 8.6 7.4 2.1 8.3 7.4 1.2 1 0 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit TLP-20 PF06088.11 OQS07977.1 - 2.6 7.9 8.5 3.7 7.4 8.5 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) PBP1_TM PF14812.6 OQS07977.1 - 7.1 7.1 11.9 12 6.3 11.9 1.6 1 1 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal NOA36 PF06524.12 OQS07977.1 - 10 5.4 9.9 12 5.1 9.9 1.1 1 0 0 1 1 1 0 NOA36 protein adh_short PF00106.25 OQS07978.1 - 2.2e-39 134.9 0.2 5.8e-29 100.9 0.1 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 OQS07978.1 - 6.8e-26 91.3 0.1 3.8e-24 85.6 0.1 2.1 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OQS07978.1 - 2.6e-09 37.2 0.1 4.6e-09 36.5 0.1 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 OQS07978.1 - 3.6e-05 23.4 0.1 6.1e-05 22.6 0.1 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 OQS07978.1 - 0.0017 17.8 0.0 0.0023 17.4 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase YjeF_N PF03853.15 OQS07978.1 - 0.0054 16.6 0.0 0.0089 15.9 0.0 1.4 1 0 0 1 1 1 1 YjeF-related protein N-terminus ApbA PF02558.16 OQS07978.1 - 0.026 14.2 0.0 0.11 12.1 0.0 1.9 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA Thioredoxin_15 PF18403.1 OQS07978.1 - 0.07 13.0 0.0 0.26 11.2 0.0 1.8 2 0 0 2 2 2 0 Thioredoxin-like domain NAD_binding_10 PF13460.6 OQS07978.1 - 0.073 13.0 0.0 0.17 11.7 0.0 1.7 1 1 0 1 1 1 0 NAD(P)H-binding QRPTase_C PF01729.19 OQS07978.1 - 0.1 12.4 0.1 0.16 11.7 0.1 1.3 1 0 0 1 1 1 0 Quinolinate phosphoribosyl transferase, C-terminal domain Shikimate_DH PF01488.20 OQS07978.1 - 0.12 12.4 0.0 0.22 11.5 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase TB2_DP1_HVA22 PF03134.19 OQS07979.1 - 3.4e-10 39.7 6.6 3.4e-10 39.7 6.6 4.1 4 1 0 4 4 4 2 TB2/DP1, HVA22 family Cwf_Cwc_15 PF04889.12 OQS07980.1 - 1.1e-68 231.7 21.5 1.7e-68 231.1 21.5 1.3 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein MFAP1 PF06991.11 OQS07980.1 - 0.012 15.5 23.7 0.016 15.1 23.7 1.2 1 0 0 1 1 1 0 Microfibril-associated/Pre-mRNA processing SDA1 PF05285.12 OQS07980.1 - 0.034 13.6 22.0 0.041 13.3 22.0 1.1 1 0 0 1 1 1 0 SDA1 PDDEXK_3 PF13366.6 OQS07980.1 - 0.04 14.3 0.1 0.078 13.3 0.1 1.4 1 0 0 1 1 1 0 PD-(D/E)XK nuclease superfamily ALMT PF11744.8 OQS07980.1 - 0.32 9.8 4.9 0.4 9.5 4.9 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter CRA PF06589.11 OQS07980.1 - 0.69 10.0 6.4 1.6 8.8 6.4 1.7 1 0 0 1 1 1 0 Circumsporozoite-related antigen (CRA) CDC45 PF02724.14 OQS07980.1 - 1.2 7.4 18.4 1.3 7.2 18.4 1.1 1 0 0 1 1 1 0 CDC45-like protein rRNA_processing PF08524.11 OQS07980.1 - 1.6 8.7 18.6 3.4 7.7 18.6 1.5 1 0 0 1 1 1 0 rRNA processing PA26 PF04636.13 OQS07980.1 - 1.9 7.3 6.8 2.2 7.1 6.8 1.2 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) RRN3 PF05327.11 OQS07980.1 - 5 5.5 10.9 5.5 5.4 10.9 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 GTP-bdg_M PF16360.5 OQS07980.1 - 7.7 7.2 12.3 0.14 12.7 2.8 2.7 2 1 0 3 3 3 0 GTP-binding GTPase Middle Region BolA PF01722.18 OQS07982.1 - 1.6e-32 111.6 0.4 2e-32 111.3 0.4 1.1 1 0 0 1 1 1 1 BolA-like protein Acyltransferase PF01553.21 OQS07983.1 - 0.0057 16.3 0.1 0.013 15.2 0.1 1.7 1 1 0 1 1 1 1 Acyltransferase DAGAT PF03982.13 OQS07983.1 - 0.018 13.9 0.1 0.027 13.4 0.1 1.4 1 1 0 1 1 1 0 Diacylglycerol acyltransferase zf-RING_2 PF13639.6 OQS07984.1 - 9.2e-12 45.1 8.2 3.3e-11 43.3 8.2 2.1 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 OQS07984.1 - 3.4e-08 33.7 7.2 2.1e-07 31.1 7.2 2.4 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 OQS07984.1 - 1.5e-07 31.2 7.7 6.4e-07 29.1 7.7 2.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 OQS07984.1 - 1.5e-06 28.0 6.9 6.9e-06 25.8 6.9 2.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 OQS07984.1 - 3.5e-06 26.8 6.1 7.7e-06 25.7 4.6 2.3 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 OQS07984.1 - 1.1e-05 25.2 5.2 5.7e-05 23.0 5.2 2.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 OQS07984.1 - 1.2e-05 25.1 4.0 3.9e-05 23.4 4.0 2.0 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 OQS07984.1 - 0.00046 19.9 6.5 0.0012 18.5 6.5 1.8 1 0 0 1 1 1 1 RING-like zinc finger zf-ANAPC11 PF12861.7 OQS07984.1 - 0.00077 19.5 6.5 0.0086 16.1 6.6 2.6 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.6 OQS07984.1 - 0.0011 19.0 4.5 0.0011 19.0 4.5 2.3 2 0 0 2 2 2 1 RING-type zinc-finger Zn_ribbon_17 PF17120.5 OQS07984.1 - 0.0014 18.2 7.4 0.0014 18.2 7.4 2.3 2 0 0 2 2 2 1 Zinc-ribbon, C4HC2 type zf-C3H2C3 PF17122.5 OQS07984.1 - 0.22 11.6 4.9 1.2 9.2 4.9 2.5 1 1 0 1 1 1 0 Zinc-finger Prok-RING_1 PF14446.6 OQS07984.1 - 9.9 6.2 10.0 1.7 8.7 1.1 3.5 3 0 0 3 3 3 0 Prokaryotic RING finger family 1 DAGAT PF03982.13 OQS07985.1 - 0.02 13.8 0.0 0.022 13.7 0.0 1.0 1 0 0 1 1 1 0 Diacylglycerol acyltransferase Gemini_AC4_5_2 PF08464.10 OQS07985.1 - 0.071 13.1 0.1 0.11 12.5 0.1 1.2 1 0 0 1 1 1 0 Geminivirus AC4/5 conserved region Trp_repressor PF01371.19 OQS07986.1 - 0.0052 16.9 0.0 0.0082 16.3 0.0 1.3 1 0 0 1 1 1 1 Trp repressor protein NAD_binding_6 PF08030.12 OQS07986.1 - 0.038 14.1 0.0 0.039 14.1 0.0 1.2 1 0 0 1 1 1 0 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 OQS07987.1 - 6e-15 55.3 0.1 1e-14 54.6 0.1 1.3 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.19 OQS07987.1 - 0.036 14.2 0.1 0.055 13.6 0.1 1.3 1 0 0 1 1 1 0 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 OQS07987.1 - 0.16 12.1 0.2 0.57 10.3 0.2 1.8 2 0 0 2 2 2 0 Ferric reductase NAD binding domain F-box PF00646.33 OQS07988.1 - 0.089 12.7 0.1 0.17 11.8 0.1 1.4 1 0 0 1 1 1 0 F-box domain Ephrin_rec_like PF07699.13 OQS07989.1 - 0.024 14.4 0.5 0.024 14.4 0.5 1.6 2 0 0 2 2 2 0 Putative ephrin-receptor like Dus PF01207.17 OQS07990.1 - 1.4e-33 116.3 0.0 4e-19 68.8 0.0 2.9 2 0 0 2 2 2 2 Dihydrouridine synthase (Dus) AIRC PF00731.20 OQS07990.1 - 1.8e-17 63.3 3.2 2.6e-17 62.8 2.1 1.9 2 0 0 2 2 2 1 AIR carboxylase Plus-3 PF03126.18 OQS07990.1 - 2.2e-15 57.1 1.5 4.7e-15 56.0 0.1 2.3 2 0 0 2 2 2 1 Plus-3 domain zf-CCCH_4 PF18044.1 OQS07990.1 - 1.3e-08 34.4 13.3 6.5e-07 29.0 0.7 3.0 3 0 0 3 3 3 2 CCCH-type zinc finger zf_CCCH_4 PF18345.1 OQS07990.1 - 0.0029 17.6 10.8 0.031 14.4 1.1 2.7 2 0 0 2 2 2 2 Zinc finger domain zf-CCCH PF00642.24 OQS07990.1 - 0.0056 16.6 7.7 0.28 11.1 0.3 2.6 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.6 OQS07990.1 - 0.0082 16.6 2.9 1.1 9.8 0.1 2.7 2 0 0 2 2 2 2 RNA-binding, Nab2-type zinc finger ubiquitin PF00240.23 OQS07991.1 - 2.3e-13 49.7 0.1 4.7e-13 48.7 0.1 1.5 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 OQS07991.1 - 0.0015 18.3 0.1 0.0023 17.7 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 OQS07991.1 - 0.0025 18.3 0.0 0.0044 17.5 0.0 1.4 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain Ubiquitin_2 PF14560.6 OQS07991.1 - 0.0083 16.6 0.0 0.018 15.5 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 OQS07991.1 - 0.017 15.2 0.0 0.033 14.3 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Ribonucleas_3_3 PF14622.6 OQS07992.1 - 7.3e-22 77.9 0.0 1.4e-21 77.0 0.0 1.3 1 0 0 1 1 1 1 Ribonuclease-III-like Ribonuclease_3 PF00636.26 OQS07992.1 - 3.7e-21 75.7 0.0 7.8e-21 74.7 0.0 1.5 1 0 0 1 1 1 1 Ribonuclease III domain Glycos_transf_1 PF00534.20 OQS07993.1 - 2.1e-23 82.7 0.0 4.5e-23 81.6 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 OQS07993.1 - 2.3e-18 66.9 0.0 5.3e-18 65.7 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 OQS07993.1 - 7.3e-09 35.8 0.1 2.6e-08 34.1 0.0 2.0 3 0 0 3 3 3 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.6 OQS07993.1 - 0.00037 21.0 0.0 0.00066 20.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.6 OQS07993.1 - 0.00039 20.7 0.0 0.0008 19.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 LSM PF01423.22 OQS07994.1 - 1.4e-16 59.9 0.6 1.7e-16 59.7 0.6 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 OQS07994.1 - 0.06 13.5 0.4 0.093 12.9 0.1 1.5 2 0 0 2 2 2 0 Ataxin 2 SM domain Peptidase_M23 PF01551.22 OQS07994.1 - 0.091 13.0 0.0 0.11 12.8 0.0 1.1 1 0 0 1 1 1 0 Peptidase family M23 DUF2046 PF09755.9 OQS07995.1 - 0.0049 16.1 6.7 0.0055 16.0 6.7 1.0 1 0 0 1 1 1 1 Uncharacterized conserved protein H4 (DUF2046) MbeD_MobD PF04899.12 OQS07995.1 - 0.013 15.6 8.1 0.021 14.9 8.1 1.4 1 0 0 1 1 1 0 MbeD/MobD like Sugar_tr PF00083.24 OQS07996.1 - 9.6e-125 417.0 21.1 1.4e-124 416.5 21.1 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OQS07996.1 - 3.3e-24 85.5 35.6 2.1e-23 82.9 33.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily AZUL PF16558.5 OQS07996.1 - 6e-11 42.4 0.2 1.1e-10 41.6 0.2 1.4 1 0 0 1 1 1 1 Amino-terminal Zinc-binding domain of ubiquitin ligase E3A zf-PARP PF00645.18 OQS07997.1 - 6.3e-08 33.4 0.0 0.0019 19.0 0.0 2.5 2 0 0 2 2 2 2 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region PHD PF00628.29 OQS07997.1 - 0.63 10.0 4.9 17 5.4 0.1 3.5 4 0 0 4 4 4 0 PHD-finger UCMA PF17085.5 OQS07999.1 - 0.018 15.0 0.9 0.04 13.9 0.9 1.5 1 0 0 1 1 1 0 Unique cartilage matrix associated protein ATP_bind_1 PF03029.17 OQS08000.1 - 0.022 14.5 0.0 0.22 11.2 0.0 2.3 2 1 0 2 2 2 0 Conserved hypothetical ATP binding protein La PF05383.17 OQS08001.1 - 3.3e-18 65.5 0.2 6.8e-18 64.5 0.2 1.5 1 0 0 1 1 1 1 La domain GAPT PF11770.8 OQS08001.1 - 0.01 15.7 1.0 0.02 14.8 1.0 1.4 1 0 0 1 1 1 0 GRB2-binding adapter (GAPT) Presenilin PF01080.17 OQS08001.1 - 4 6.1 7.5 6.6 5.4 7.5 1.4 1 0 0 1 1 1 0 Presenilin TAN PF11640.8 OQS08002.1 - 0.013 15.7 1.0 0.017 15.3 1.0 1.2 1 0 0 1 1 1 0 Telomere-length maintenance and DNA damage repair SYF2 PF08231.12 OQS08003.1 - 2e-27 96.5 14.2 2e-27 96.5 14.2 2.6 1 1 1 2 2 2 1 SYF2 splicing factor Delta_lysin PF05372.11 OQS08004.1 - 0.058 12.7 0.1 0.18 11.1 0.1 1.8 1 0 0 1 1 1 0 Delta lysin family CLASP_N PF12348.8 OQS08005.1 - 3e-09 36.8 3.9 4.8e-07 29.6 0.1 3.7 3 1 0 3 3 3 2 CLASP N terminal Cnd1 PF12717.7 OQS08005.1 - 7e-05 22.9 7.5 1.4 9.0 1.5 5.6 6 1 1 7 7 7 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 OQS08005.1 - 0.00022 21.2 6.8 41 4.8 0.0 8.2 10 0 0 10 10 10 0 HEAT repeat IFRD PF05004.13 OQS08005.1 - 0.004 16.3 9.2 0.096 11.8 1.4 4.6 5 0 0 5 5 5 1 Interferon-related developmental regulator (IFRD) DUF2587 PF10759.9 OQS08005.1 - 0.1 12.1 0.8 0.23 11.0 0.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2587) Dopey_N PF04118.14 OQS08005.1 - 0.11 11.5 0.1 21 4.1 0.0 3.1 4 0 0 4 4 4 0 Dopey, N-terminal RTP1_C1 PF10363.9 OQS08005.1 - 0.24 11.6 1.4 8.9 6.5 0.0 3.5 3 1 0 3 3 3 0 Required for nuclear transport of RNA pol II C-terminus 1 HEAT_EZ PF13513.6 OQS08005.1 - 0.54 10.8 2.6 2.4e+02 2.4 0.1 5.3 6 0 0 6 6 6 0 HEAT-like repeat CcdA PF07362.12 OQS08005.1 - 3 8.3 4.7 2.5 8.6 0.5 2.8 3 0 0 3 3 3 0 Post-segregation antitoxin CcdA Med10 PF09748.9 OQS08007.1 - 1.4e-05 25.0 0.0 2e-05 24.6 0.0 1.1 1 0 0 1 1 1 1 Transcription factor subunit Med10 of Mediator complex TALPID3 PF15324.6 OQS08007.1 - 0.73 7.4 3.8 0.68 7.5 3.8 1.1 1 0 0 1 1 1 0 Hedgehog signalling target Ank_5 PF13857.6 OQS08008.1 - 0.00077 19.7 0.1 0.1 13.0 0.0 2.5 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 OQS08008.1 - 0.0012 19.3 0.3 0.0064 17.0 0.1 2.2 2 1 0 2 2 2 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 OQS08008.1 - 0.0067 17.0 0.2 0.01 16.4 0.2 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) DUF2972 PF11186.8 OQS08008.1 - 0.012 15.6 0.1 0.014 15.3 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2972) Peptidase_C23 PF05379.11 OQS08008.1 - 0.089 12.9 0.2 0.25 11.5 0.0 1.7 2 0 0 2 2 2 0 Carlavirus endopeptidase Ank_3 PF13606.6 OQS08008.1 - 0.11 13.2 1.1 0.52 11.0 0.0 2.7 4 0 0 4 4 4 0 Ankyrin repeat VLPT PF07122.11 OQS08008.1 - 0.14 11.9 0.3 0.65 9.8 0.0 2.2 2 0 0 2 2 2 0 Variable length PCR target protein (VLPT) SNARE_assoc PF09335.11 OQS08010.1 - 8.2e-15 55.4 3.1 8.2e-15 55.4 3.1 1.9 3 0 0 3 3 3 1 SNARE associated Golgi protein CPP1-like PF11833.8 OQS08010.1 - 1.8 8.2 5.4 0.3 10.7 0.4 2.1 2 1 0 2 2 2 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like Aminotran_1_2 PF00155.21 OQS08011.1 - 3.9e-36 125.0 0.0 5.2e-36 124.6 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 OQS08011.1 - 0.00069 19.0 0.0 0.0016 17.8 0.0 1.7 1 1 0 1 1 1 1 Beta-eliminating lyase Spherulin4 PF12138.8 OQS08011.1 - 0.12 12.0 0.0 0.19 11.3 0.0 1.4 1 0 0 1 1 1 0 Spherulation-specific family 4 53-BP1_Tudor PF09038.10 OQS08012.1 - 0.13 12.2 0.0 0.17 11.8 0.0 1.1 1 0 0 1 1 1 0 Tumour suppressor p53-binding protein-1 Tudor TMEM18 PF14770.6 OQS08013.1 - 3.1e-35 120.7 3.5 3.9e-35 120.4 3.5 1.1 1 0 0 1 1 1 1 Transmembrane protein 18 PrgI PF12666.7 OQS08013.1 - 2.5 8.9 6.9 0.96 10.2 0.2 2.1 1 1 1 2 2 2 0 PrgI family protein Glyco_hydro_6 PF01341.17 OQS08014.1 - 1.9e-11 44.2 0.5 3.3e-11 43.5 0.5 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 6 YhhN PF07947.14 OQS08014.1 - 0.11 12.1 0.0 0.2 11.3 0.0 1.3 1 0 0 1 1 1 0 YhhN family LsmAD PF06741.13 OQS08015.1 - 1.8e-25 89.3 2.7 3.4e-25 88.4 2.7 1.5 1 0 0 1 1 1 1 LsmAD domain SM-ATX PF14438.6 OQS08015.1 - 1.7e-12 47.3 0.0 4.2e-12 46.0 0.0 1.7 1 0 0 1 1 1 1 Ataxin 2 SM domain Gemin7 PF11095.8 OQS08015.1 - 6.8e-05 22.7 0.2 0.0009 19.1 0.1 2.2 2 0 0 2 2 2 1 Gem-associated protein 7 (Gemin7) LSM14 PF12701.7 OQS08015.1 - 0.00017 21.6 0.0 0.00028 20.9 0.0 1.4 1 0 0 1 1 1 1 Scd6-like Sm domain DUF150_C PF17384.2 OQS08015.1 - 0.0099 16.0 0.0 0.018 15.2 0.0 1.3 1 0 0 1 1 1 1 RimP C-terminal SH3 domain PAM2 PF07145.15 OQS08015.1 - 0.06 13.1 0.2 0.06 13.1 0.2 3.1 2 1 1 3 3 3 0 Ataxin-2 C-terminal region LSM PF01423.22 OQS08015.1 - 0.094 12.4 0.0 0.17 11.6 0.0 1.3 1 0 0 1 1 1 0 LSM domain MMR_HSR1 PF01926.23 OQS08016.1 - 2.6e-14 53.2 0.0 7.3e-13 48.6 0.0 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 OQS08016.1 - 2e-06 27.8 0.0 0.00021 21.2 0.0 2.6 2 0 0 2 2 2 1 RsgA GTPase FeoB_N PF02421.18 OQS08016.1 - 4.2e-06 26.4 0.1 1.2e-05 24.8 0.0 1.8 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.23 OQS08016.1 - 0.00057 20.0 0.6 0.0014 18.7 0.1 2.0 2 0 0 2 2 2 1 Dynamin family PolC_DP2 PF03833.13 OQS08016.1 - 0.00098 17.1 3.6 0.0015 16.5 3.6 1.2 1 0 0 1 1 1 1 DNA polymerase II large subunit DP2 zf-B_box PF00643.24 OQS08016.1 - 0.021 15.0 7.3 0.049 13.8 7.3 1.6 1 1 0 1 1 1 0 B-box zinc finger MCM2_N PF12619.8 OQS08016.1 - 0.027 14.8 7.2 0.18 12.1 0.0 2.4 2 0 0 2 2 2 0 Mini-chromosome maintenance protein 2 zf-RRPl_C4 PF17026.5 OQS08016.1 - 0.031 14.4 2.7 0.066 13.3 2.7 1.5 1 0 0 1 1 1 0 Putative ribonucleoprotein zinc-finger pf C4 type Crust_neurohorm PF01147.17 OQS08016.1 - 0.045 13.6 0.4 0.099 12.5 0.4 1.5 1 0 0 1 1 1 0 Crustacean CHH/MIH/GIH neurohormone family NOG1 PF06858.14 OQS08016.1 - 0.14 11.9 0.0 1.1 9.1 0.0 2.5 2 0 0 2 2 2 0 Nucleolar GTP-binding protein 1 (NOG1) PAS_9 PF13426.7 OQS08016.1 - 0.16 12.2 0.0 0.76 10.1 0.0 2.1 2 0 0 2 2 2 0 PAS domain zf-UBR PF02207.20 OQS08016.1 - 0.23 11.7 2.9 0.55 10.4 2.9 1.6 1 0 0 1 1 1 0 Putative zinc finger in N-recognin (UBR box) Stig1 PF04885.13 OQS08016.1 - 0.59 10.6 9.0 0.051 14.1 3.8 1.8 2 0 0 2 2 2 0 Stigma-specific protein, Stig1 Ank_2 PF12796.7 OQS08018.1 - 3.9e-18 65.8 6.3 4.2e-06 27.2 0.1 5.8 3 2 3 7 7 7 5 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OQS08018.1 - 8.6e-14 50.3 12.0 0.36 11.5 0.0 9.7 9 0 0 9 9 9 4 Ankyrin repeat Ank PF00023.30 OQS08018.1 - 1.9e-09 37.6 13.1 0.81 10.3 0.0 7.5 8 0 0 8 8 8 3 Ankyrin repeat Ank_4 PF13637.6 OQS08018.1 - 1.8e-07 31.6 7.7 2.4 8.8 0.1 6.0 5 1 1 6 6 6 4 Ankyrin repeats (many copies) Pkinase PF00069.25 OQS08018.1 - 2.4e-07 30.4 0.0 7.9e-07 28.7 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 OQS08018.1 - 2.7e-06 26.9 0.4 6.1e-06 25.7 0.0 1.8 2 0 0 2 2 2 1 Kinase-like Ank_5 PF13857.6 OQS08018.1 - 0.0083 16.4 6.9 22 5.5 0.0 6.6 7 1 1 8 8 8 0 Ankyrin repeats (many copies) MCU PF04678.13 OQS08018.1 - 0.046 13.8 1.9 0.082 13.0 1.9 1.4 1 0 0 1 1 1 0 Mitochondrial calcium uniporter DUF3450 PF11932.8 OQS08018.1 - 0.14 11.4 2.4 0.23 10.7 2.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Mito_carr PF00153.27 OQS08019.1 - 5.9e-61 202.4 0.0 3e-24 84.8 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Pkinase PF00069.25 OQS08020.1 - 4.3e-07 29.6 0.0 4.5e-07 29.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQS08020.1 - 0.072 12.4 0.0 0.076 12.3 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase Neurochondrin PF05536.11 OQS08020.1 - 0.13 10.6 0.0 0.13 10.6 0.0 1.1 1 0 0 1 1 1 0 Neurochondrin DUF1040 PF06288.13 OQS08021.1 - 0.34 11.3 4.8 0.32 11.4 0.5 3.3 2 1 0 3 3 3 0 Protein of unknown function (DUF1040) HrpF PF06266.12 OQS08021.1 - 3.4 8.0 8.2 0.43 10.9 0.2 3.7 4 0 0 4 4 4 0 HrpF protein Nuc_sug_transp PF04142.15 OQS08022.1 - 0.00023 20.4 6.3 0.00031 20.0 6.3 1.2 1 0 0 1 1 1 1 Nucleotide-sugar transporter TPT PF03151.16 OQS08022.1 - 0.0011 18.4 12.9 0.0015 17.9 12.5 1.4 1 1 1 2 2 2 2 Triose-phosphate Transporter family DUF2663 PF10864.8 OQS08022.1 - 8.1 6.9 11.1 0.83 10.1 0.5 2.9 1 1 3 4 4 4 0 Protein of unknown function (DUF2663) Eapp_C PF10238.9 OQS08023.1 - 3.2e-27 95.4 8.9 3.7e-21 75.8 5.0 2.4 1 1 1 2 2 2 2 E2F-associated phosphoprotein Yippee-Mis18 PF03226.14 OQS08023.1 - 8.3e-05 22.8 1.8 0.00016 21.8 1.8 1.4 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly FUR PF01475.19 OQS08023.1 - 0.4 10.8 7.3 0.32 11.2 0.9 2.3 2 0 0 2 2 2 0 Ferric uptake regulator family APC_u15 PF16636.5 OQS08023.1 - 0.71 10.4 3.9 0.55 10.7 0.9 2.1 1 1 1 2 2 2 0 Unstructured region on APC between APC_crr regions 5 and 6 Lar_restr_allev PF14354.6 OQS08023.1 - 3.6 8.0 8.6 2.5 8.5 3.8 2.4 1 1 1 2 2 2 0 Restriction alleviation protein Lar Pkinase PF00069.25 OQS08024.1 - 5.3e-47 160.4 0.0 6.3e-47 160.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OQS08024.1 - 1.8e-24 86.4 0.0 2.3e-24 86.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase DSHCT PF08148.12 OQS08024.1 - 0.00024 20.8 0.0 0.0004 20.1 0.0 1.3 1 0 0 1 1 1 1 DSHCT (NUC185) domain Haspin_kinase PF12330.8 OQS08024.1 - 0.01 14.8 0.1 0.014 14.4 0.1 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Kdo PF06293.14 OQS08024.1 - 0.026 13.9 0.0 0.043 13.1 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF4131 PF13567.6 OQS08025.1 - 0.05 13.3 0.9 0.2 11.3 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) YPEB PF14620.6 OQS08026.1 - 0.0026 17.2 1.8 0.0039 16.6 1.8 1.2 1 0 0 1 1 1 1 YpeB sporulation PUD1_2 PF18457.1 OQS08026.1 - 0.0053 16.8 0.0 0.0098 15.9 0.0 1.4 1 0 0 1 1 1 1 Up-Regulated in long-lived daf-2 betaPIX_CC PF16523.5 OQS08026.1 - 1.2 9.0 7.6 1.1 9.1 2.0 2.8 2 1 0 2 2 2 0 betaPIX coiled coil DUF5315 PF17242.2 OQS08026.1 - 2.1 8.2 8.3 0.49 10.3 0.2 3.5 3 0 0 3 3 3 0 Disordered region of unknown function (DUF5315) TSC22 PF01166.18 OQS08026.1 - 2.9 8.3 5.8 12 6.2 0.7 2.7 1 1 1 2 2 2 0 TSC-22/dip/bun family YlqD PF11068.8 OQS08026.1 - 3.9 7.9 11.6 10 6.5 11.6 1.7 1 0 0 1 1 1 0 YlqD protein Glyco_hydro_11 PF00457.17 OQS08029.1 - 2.5e-73 245.5 17.6 2.5e-73 245.5 17.6 1.7 2 0 0 2 2 2 1 Glycosyl hydrolases family 11 Glyco_hydro_62 PF03664.13 OQS08029.1 - 6.5e-62 209.3 3.5 1e-61 208.7 3.5 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 62 PT PF04886.12 OQS08029.1 - 0.00021 20.7 33.5 0.001 18.6 33.5 2.0 1 1 0 1 1 1 1 PT repeat adh_short PF00106.25 OQS08030.1 - 7.3e-42 143.0 0.2 9.7e-42 142.6 0.2 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OQS08030.1 - 4.9e-29 101.5 0.1 5.7e-29 101.3 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OQS08030.1 - 0.0071 16.3 0.0 0.0098 15.8 0.0 1.3 1 0 0 1 1 1 1 KR domain Methyltransf_11 PF08241.12 OQS08030.1 - 0.03 15.0 0.1 0.093 13.4 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain Ldh_1_N PF00056.23 OQS08030.1 - 0.034 14.2 0.0 0.06 13.4 0.0 1.3 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain Plasmodium_Vir PF05795.11 OQS08031.1 - 2.1 7.7 9.5 4.7 6.5 9.4 1.6 1 1 0 1 1 1 0 Plasmodium vivax Vir protein adh_short PF00106.25 OQS08032.1 - 1.4e-42 145.4 3.3 2.3e-42 144.6 3.3 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OQS08032.1 - 1.1e-33 116.7 4.0 1.8e-33 116.1 4.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OQS08032.1 - 1.1e-07 31.9 0.9 2.3e-07 30.9 0.9 1.4 1 0 0 1 1 1 1 KR domain # # Program: hmmscan # Version: 3.2.1 (June 2018) # Pipeline mode: SCAN # Query file: /oak/stanford/groups/akundaje/marinovg/genomes/Oomycete/Thraustotheca_clavata-Thrcla_v1/GCA_002081575.1_Thrcla_v1_protein.faa # Target file: /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm # Option settings: /oak/stanford/groups/akundaje/marinovg/programs/hmmer-3.2.1/bin/hmmscan -o /oak/stanford/groups/akundaje/marinovg/genomes/Oomycete/Thraustotheca_clavata-Thrcla_v1/GCA_002081575.1_Thrcla_v1_protein.PFam32-A --tblout /oak/stanford/groups/akundaje/marinovg/genomes/Oomycete/Thraustotheca_clavata-Thrcla_v1/GCA_002081575.1_Thrcla_v1_protein.PFam32-A.tblout --cpu 20 /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm /oak/stanford/groups/akundaje/marinovg/genomes/Oomycete/Thraustotheca_clavata-Thrcla_v1/GCA_002081575.1_Thrcla_v1_protein.faa # Current dir: /oak/stanford/groups/akundaje/marinovg/genomes # Date: Mon Mar 25 11:05:05 2019 # [ok]